bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prostate cancer with low burden skeletal disease at diagnosis: outcome of concomitant radiotherapy on primary tumor and metastases
Authors: Deantoni Chiara Lucrezia , Fodor Andrei , Cozzarini Cesare , Fiorino Claudio , Brombin Chiara , Di Serio Clelia , Calandrino Riccardo , Di Muzio Nadia 
Published: January 2020

Objective:
To evaluate toxicity and clinical outcome in synchronous bone only oligometastatic (≤2 lesions) prostate cancer patients, simultaneously irradiated to prostate/prostatic bed, lymph nodes and bone metastases.

Methods:
From 2/2009 to 6/2015, 39 bone only prostate cancer patients underwent radiotherapy (RT) at “radical” doses to bone metastases (median 2 Gy equivalent dose, EQD2&gt;40Gy, α/β = 1,5), nodes, and prostate/prostatic bed, within the same RT course, in association with androgen deprivation therapy (ADT).
Biochemical relapse-free survival, clinical relapse-free survival, freedom from distant metastases and overall survival were evaluated.

Results:
After a median follow-up of 46.5 (1.2–103.6) months, 5 patients died from disease progression, 10 experienced biochemical relapse, 19, still in ADT, presented undetectable prostate-specific antigen (PSA) at the last follow-up. Five patients who discontinued ADT after a median of 34 months (5.8–41) are free from biochemical relapse.
The 4 year Kaplan–Meier estimates of biochemical relapse-free survival, clinical relapse-free survival, freedom from distant metastases and overall survival were 53.3%, 65.7%, 73.4% and 82.4% respectively.
No Grade &gt; 2 acute events and only two severe late urinary events were recorded, not due to the concomitant treatment of primary and metastatic disease.

Conclusion:
Our results suggest that “radical” and synchronous irradiation of primitive tumor and metastatic disease may be a valid approach in synchronous bone only prostate cancer patients, showing mild toxicity profile and promising survival results.

Advances in knowledge:
To the best of our knowledge, this is the first analysis of clinical outcome in synchronous bone-only metastasis (neither nodal nor visceral) patients at diagnosis, treated with radical RT to all disease, associated to ADT.
Perspectivism of the Renaissance Thought
Authors: Menčik David 
Published: January 2020

The starting point of the essay is clarifying the difference between the mono-perspective and multi-perspective vision of reality. Off-course the terms perspective, mono-perspective and multi-perspective are not self-explanatory and the meanings of these terms need to be formally analysed. After making the formal difference between mono-perspective thinking and multi-perspective thinking a content difference needs to be made. Namely, why is the Renaissance vision of reality multi-perspective and the Middle-Age vision of reality mono-perspective? The answer to this question needs to be given by the analysis of the original works of the Renaissance thinkers. Our undertaking will not be limited in analysing only one discourse but following the subject from a methodological point of view in a multi-perspectivism way. Therefore, three different discourses will be analysed: The discourse of philosophical anthropology with Mirandola’s vision of man as a paradigmatic example-The discourse of philosophy of nature, with Bruno’s vision of the universe as a paradigmatic example-The discourse of art history in which four paintings will be analysed: these paintings can be considered of having philosophical, value because they provide a picturesque representation of what the Renaissance “world” was really like.
Instituciones en crisis y acción colectiva frente a las migraciones globales. El caso de la llegada de haitianos a Tijuana, B.C., 2016-2017
Authors: Silva Hernández Aída , Padilla Orozco Vianney 
Published: January 2020

¿De qué manera las nuevas expresiones de la migración global generan formas de acción colectiva igualmente inusitadas? A mediados de 2016 empezaron a llegar a Tijuana, B.C. (México) cientos de personas de origen haitiano. Las particularidades de su estatus migratorio y el volumen de arribo colocaron a las instituciones civiles y gubernamentales en una crisis ante la inexistencia de políticas específicas para su atención. Partiendo de una discusión teórica-conceptual de acción colectiva y desde una perspectiva metodológica cualitativa, el objetivo del artículo es analizar las relaciones interinstitucionales y el manejo estratégico de recursos de las diversas formas de asociación que surgen en una coyuntura como esta. El estudio muestra cómo en un contexto de crisis institucional las expresiones emergentes de acción colectiva se construyen a partir de redes para responder a necesidades de corto y mediano plazo de la población afectada; así mismo, se aceleran los procesos de organización cívica fundamentados en la solidaridad y se promueve la participación ciudadana a partir de principios identitarios propios de lugares con una larga experiencia migratoria.
Otros sujetos de derecho o personas (?)
Authors: Ceballos Rosero Franco Alirio 
Published: January 2020

La existencia de nuevos sujetos de derecho o personas es evidente en múltiples ordenamientos jurídicos, ya que además de las personas naturales y jurídicas, se han abierto camino como sujetos de derecho o personas comunidades étnicas, generaciones futuras, los seres sintientes y algunos ecosistemas con los que la humanidad comparte vida, hábitats y dependencia. Los derechos étnicos, ambientales, de la naturaleza y de protección animal han abierto la posibilidad teórica para desantropologizar el derecho, posibilitando –inclusive– perspectivas teóricas mucho más ambiciosas relacionadas con las inteligencias artificiales, androides/robots o los seres espirituales. El presente documento es una aproximación teórica para una teoría heterogénea del concepto de persona que desborde sus límites antropocéntricos.
Entre la juridificación y la profundización de la democracia social: elementos para pensar los conflictos alrededor de los manuales de convivencia en las instituciones educativas y los derechos fundamentales de los estudiantes
Authors: Aguirre Román Javier Orlando , Pabón Mantilla Ana Patricia , Moreno Bernal Iveth Paola 
Published: January 2020

El presente texto tiene como objetivo central abordar el debate acerca de la definición de reglas en los manuales de convivencia y las formas de mediar conflictos entre los distintos actores del sistema escolar en Colombia. El análisis describe las tensiones entre legitimidad y democracia por un lado y disciplina y autonomía de las instituciones por otro, a partir de dos referentes teóricos, el planteamiento de Habermas sobre la noción de juridificación y de Bobbio sobre democracia social. La investigación es de tipo teórico, se propone una reflexión desde la hermenéutica crítica de los resultados del análisis documental de las decisiones de la jurisprudencia colombiana sobre manuales de convivencia. La revisión de los referentes filosóficos y el análisis de la forma en que se ha abordado el conflicto en las instituciones escolares permitieron concluir que a pesar de que exista una juridificación de la escuela que se visibiliza con la intervención vía tutela contra las instituciones, en muchas ocasiones esto ha sido una respuesta de los distintos actores para frenar la ausencia de democracia social en las instituciones escolares.
The Future Ambiguity Effect: How Narrow Payoff Ranges Increase Future Payoff Appeal
Authors: Liu Yuanyuan , Heath Timothy B. , Onculer Ayse 
Published: January 2020

Increasing a current payoff’s ambiguity from a precise value (e.g., $150) to a range (e.g., $140–$160) generally reduces the payoff’s appeal, as does delaying the payoff from, for example, now to one year from now. However, we report five studies in which adding small ranges to future payoffs increases future payoff appeal, an emergent property designated the future ambiguity effect. This effect generalizes across various choice sets, payoff levels, and delays, and it prevails even when a future smaller ambiguous payoff is preferred more than a future larger precise payoff. Two underlying processes are proposed and supported: (1) the payoff ambiguity’s explicit risk of receiving a smaller payoff distracts people from the future’s larger implicit risk of receiving nothing, and (2) payoff ambiguity restores some of the excitement lost to the future’s psychological distance. Nonetheless, the future ambiguity effect is not universal, given that larger ranges can reduce and even eliminate it (boundary condition). This paper was accepted by Yuval Rottenstreich, judgment and decision making.
Effects of Psycho-educational Intervention on Post-traumatic Stress Disorder Symptoms among Secondary School Students Exposed to Conflict in Kano Metropolis, Nigeria
Authors: Mebu Valentine Ayo 
Published: January 2020

<p style="text-align:justify">Insurgency and armed conflict in Northern Nigeria especially Kano metropolis have exposed many secondary school students to trauma related experiences and post-traumatic stress disorder (PTSD). It is estimated that about 13,000 persons have been killed and about 981,416 internally displaced persons (IDPs) are living in the various camps in Northern Nigeria (NEMA, 2015). The profound impact of the trauma experienced by these students on their mental health informed the need for the psycho-education intervention. The objective of this study was to determine the effects of psycho-educational intervention on PTSD symptoms among secondary school students exposed to conflict in Kano metropolis and to examine the effects of psycho-education intervention in reduction of re-experiencing, hyper-arousal and avoidance symptoms. A pre-test and post-test control group design was adopted for this study. A sample of 40 research participants (male=19, female=21) were selected for the study. These research participants were drawn from secondary schools clustered within the community where conflicts have taken place. The instrument for data collection was the adapted version of the University of California at Los Angeles post-traumatic stress Disorder Reaction Index (UCLA PTSD Reaction Index). The UCLA PTSD Reaction Index measured PTSD symptoms. Result obtained after testing the hypotheses showed that there was a significant difference in the PTSD mean scores of students exposed to psychoeducational intervention (Mean= 22.40, Standard deviation = 4.47, Standard error = .998) and those not exposed to the intervention (Mean = 38.90, Standard deviation = 14.835, Standard error = 3.317), t (38) = -4.763, p < .0001 (two-tailed), Effect size is r = .61. It is important to provide professional and psychosocial support to students who developed mental health problems due to exposure to conflict.</p>
Relative impact of channel symbol rate on transmission capacity
Authors: Gerard Thomas , Semrau Daniel , Sillekens Eric , Edwards Adrian , Pelouch Wayne , Barnes Stuart , Killey Robert I. , Lavery Domaniç , Bayvel Polina , Galdino Lidia 
Published: January 2020

Through C+L band transmission experiments and theoretical modeling, we investigate the impact of channel symbol rate (30, 40, 60, and 85 GBd) on the performance of data center interconnection, metropolitan, and core network distances. Two different transponder architectures are investigated: (a) single-carrier receiver and (b) multi-carrier receiver, where multiple subcarriers are received together in a single wideband receiver. The architectures of both receivers experience a reduction in the achievable information rate as the channel symbol rate increases due to dominating transceiver noise; this holds over all tested transmission distances. However, the multi-carrier receiver shows a weaker performance dependency on symbol rate, as receiver-related impairments dominate. When testing the single-carrier receiver after 630 km, we find that by increasing the channel symbol rate from 40 to 85 GBd, gross capacity decreases by 16%; however, the required number of transceivers to fill the transmission window decreases by 52%. Using the multi-carrier receiver reduces receiver count further. This potentially impacts the cost and complexity of deploying fully loaded transmission systems.
Wide-field ophthalmic space-division multiplexing optical coherence tomography
Authors: Jerwick Jason , Huang Yongyang , Dong Zhao , Slaudades Adrienne , Brucker Alexander J. , Zhou Chao 
Published: January 2020

High-speed ophthalmic optical coherence tomography (OCT) systems are of interest because they allow rapid, motion-free, and wide-field retinal imaging. Space-division multiplexing optical coherence tomography (SDM-OCT) is a high-speed imaging technology that takes advantage of the long coherence length of microelectromechanical vertical cavity surface emitting laser sources to multiplex multiple images along a single imaging depth. We demonstrate wide-field retinal OCT imaging, acquired at an effective A-scan rate of 800,000 A-scans/s with volumetric images covering up to

12.5

mm
×
7.4

mm

on the retina and captured in less than 1 s. A clinical feasibility study was conducted to compare the ophthalmic SDM-OCT with commercial OCT systems, illustrating the high-speed capability of SDM-OCT in a clinical setting.
High-efficiency and high-power single-frequency fiber laser at 1.6  μm based on cascaded energy-transfer pumping
Authors: Guan Xianchao , Zhao Qilai , Lin Wei , Tan Tianyi , Yang Changsheng , Ma Pengfei , Yang Zhongmin , Xu Shanhui 
Published: January 2020

In this paper, a technique combining the cascaded energy-transfer pumping (CEP) method and master-oscillator power-amplifier (MOPA) configuration is proposed for power scaling of 1.6-μm-band single-frequency fiber lasers (SFFLs), where the

Er

3
+

ion has a limited gain. The CEP technique is fulfilled by coupling a primary signal light at 1.6 μm and a C-band auxiliary laser. The numerical model of the fiber amplifier with the CEP technique reveals that the energy transfer process involves the pump competition and the in-band particle transition between the signal and auxiliary lights. Moreover, for the signal emission, the population density in the upper level is enhanced, and the effective population inversion is achieved thanks to the CEP. A single-frequency MOPA laser at 1603 nm with an output power of 52.6 W and an improved slope efficiency of 30.4% is experimentally obtained through the CEP technique. Besides, a laser linewidth of 5.2 kHz and a signal-to-auxiliary laser ratio of 60.7 dB are obtained at the maximum output power. The proposed technique is anticipated to be promising for increasing the slope efficiency and power scaling for fiber lasers operating at L band.
Versatile on-chip light coupling and (de)multiplexing from arbitrary polarizations to controlled waveguide modes using an integrated dielectric metasurface
Authors: Meng Yuan , Liu Zhoutian , Xie Zhenwei , Wang Ride , Qi Tiancheng , Hu Futai , Kim Hyunseok , Xiao Qirong , Fu Xing , Wu Qiang , Bae Sang-Hoon , Gong Mali , Yuan Xiaocong 
Published: January 2020

Metasurfaces have found broad applicability in free-space optics, while its potential to tailor guided waves remains barely explored. By synergizing the Jones matrix model with generalized Snell’s law under the phase-matching condition, we propose a universal design strategy for versatile on-chip mode-selective coupling with polarization sensitivity, multiple working wavelengths, and high efficiency concurrently. The coupling direction, operation frequency, and excited mode type can be designed at will for arbitrary incident polarizations, outperforming previous technology that only works for specific polarizations and lacks versatile mode controllability. Here, using silicon-nanoantenna-patterned silicon-nitride photonic waveguides, we numerically demonstrate a set of chip-scale optical couplers around 1.55 μm, including mode-selective directional couplers with high coupling efficiency over 57% and directivity about 23 dB. Polarization and wavelength demultiplexer scenarios are also proposed with 67% maximum efficiency and an extinction ratio of 20 dB. Moreover, a chip-integrated twisted light generator, coupling free-space linear polarization into an optical vortex carrying

1
ℏ

orbital angular momentum (OAM), is also reported to validate the mode-control flexibility. This comprehensive method may motivate compact wavelength/polarization (de)multiplexers, multifunctional mode converters, on-chip OAM generators for photonic integrated circuits, and high-speed optical telecommunications.
Strong mechanical squeezing in an optomechanical system based on Lyapunov control
Authors: Xiong Biao , Li Xun , Chao Shi-Lei , Yang Zhen , Zhang Wen-Zhao , Zhang Weiping , Zhou Ling 
Published: January 2020

We propose a scheme to generate strong squeezing of a mechanical oscillator in an optomechanical system through Lyapunov control. Frequency modulation of the mechanical oscillator is designed via Lyapunov control. We show that the momentum variance of the mechanical oscillator decreases with time evolution in a weak coupling case. As a result, strong mechanical squeezing is realized quickly (beyond 3 dB). In addition, the proposal is immune to cavity decay. Moreover, we show that the obtained squeezing can be detected via an ancillary cavity mode with homodyne detection.
Projeto Corpo e(m) Movimento
Authors: Gomes Luiza Bernardes de Andrade , Silva Patrícia Chavarelli Vilela da 
Published: January 2020

Este relato busca demonstrar a importância de um processo educacional de/em/na dança para o desenvolvimento das crianças como indivíduos. Pretende também apontar a dificuldade de acesso a esse tipo de atividade por pessoas de baixa renda e da periferia, ressaltando a importância de projetos que viabilizem a educação pela arte a algumas minorias. Discorre sobre procedimentos de ensino-aprendizagem em dança, mais especificamente sobre improvisação em dança no primeiro ciclo da educação infantil, procurando compreender como o modo de condução das experiências potencializa a construção de conhecimento e a criatividade da criança. Também ressaltamos a importância de se repensar determinados conceitos e pré-conceitos para tornar o estudo da dança acessível à criança, em um momento tão importante do processo de desenvolvimento do indivíduo, como o período da infância. O relato tem como base as atividades do Projeto Corpo e(m) Movimento, realizado em uma escola da rede estadual de ensino em Uberlândia, Minas Gerais.
Best Choice for Investment-Islamic Equity or Sukuk?
Authors: Khoiruddin Akhmad Yusuf 
Published: January 2020

Islamic capital market is an important part in the development of Islamic economics especially in providing a mobilization of fund to the efficient economic source and provides liquidity to the Islamic finance institution such as Islamic bank etc. There are two main instrumens in Islamic capital market namely Islamic equity and sukuk. In investmet point of view, the raise question is what is the best choises of investment between islamic equity and sukuk. The objective of this research to describe the return and the risk profile of Islamic equity and sukuk in the world. Second, this paper will conduct study about the chance to arrange Islamic portfolio investment consist of two securities namely, sukuk and Islamic equity. To analyze this, researchers will use some tools in capital market theories including portfolio theory, minimum variance portfolio, Sharpe, Jansen, Treynor and RAP model. Thirdly, this paper will test the different level of return between Islamic equity and sukuk. The main instrument is statistical analysis, and SPSS. This research found that based on quantitative analysis Sukuk provides a better return as well as lower risk. However, in the short term, islamic equity is often provide a higher return than sukuk. From the several measurement tools, this research also finds that sukuk has a better performance than islamic equity. In contrast, statistical testing shows that there are no significance differences return between Islamic equity and sukuk from 2005 till 2010. Therefore, this research suggest that investor/peple who want to increase their wealth and prefer to invest in islamic capital market, they should make a islamic portfolio include some securities component, sukuk, islamic equity, islamic unit trust, islamic etf, etc.
ANALISIS PENGARUH KETERBUKAAN EKONOMI TERHADAP PERTUMBUHAN EKONOMI (STUDI KASUS: ASEAN TAHUN 2007 – 2017)
Authors: Purnomo Rahmi Nuraini 
Published: January 2020

The era of globalization demands an increasingly broad economic openness from every country in the world, both openness in foreign trade (trade openness) and openness to the financial sector. In theory, economic openness benefits all countries involved. The advantages of trade openness include opening up wider market access to achieving higher levels of efficiency and economic competitiveness, as well as opportunities for greater employment. Openness in the financial sector can encourage the entry of foreign capital (capital inflow), and accelerate the occurrence of capital accumulation and technology transfer. This study aims to analyze the effect of economic openness on economic growth in ASEAN (Indonesia, Malaysia, Singapore, Thailand, Philippines, Vietnam, Brunei Darussalam, Cambodia) for the period 2000 - 2017. This study uses panel data regression analysis with a fixed effect approach. The method in this study uses quantitative research by conducting hypothesis testing. The data used are secondary data from ASEAN countries in 2007-2017 by looking at publications at the World Bank. This study uses panel data, where the panel data is a combination of cross section and time series data. The analytical tool used is panel data regression analysis using the Eviews9 program. Then the best panel data regression model is estimated. From the stages of analysis carried out, the results of data analysis showed that the results of the panel data estimation selected the best model were Fixed Effext Model (FEM). Hypothesis testing of the results of the Trade Openness (TO) and Foreign Direct Investment (FDI) model have a positive and significant effect on ASEAN Economic Growth (G), while the government expenditure variable (GOV) has no significant positive effect. The inflation variable (INF) has no effect on economic growth.