bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers and facilitators to implementation of a multifaceted nurse‐led intervention in acute care hospitals aimed at reducing indwelling urinary catheter use: A qualitative study
Authors: Parker Vicki , Giles Michelle , King Jennie , Bantawa Kamana 
Published: May 2020

AbstractBackgroundIt is essential to evaluate the ways in which practice changes are implemented and received in and across contexts, identifying barriers and enablers, and mechanisms for enhancing success.AimTo provide insights into the experiences of clinicians in implementing a multifaceted bundled urinary catheter care intervention in four acute care hospitals in New South Wales, Australia.MethodsThe catheter care bundle was implemented using a pre‐ and postintervention study design. The intervention was implemented in all adult inpatient wards, emergency departments and operating theatres of four hospitals. The bundle consisted of an integrated set of evidence‐based practices to assist clinicians in making better informed decisions related to catheter insertion, care and removal practices. Focus groups at each participating hospital evaluated the implementation processes from the clinicians’ perspective, identifying barriers and enablers to successful implementation.ResultsEight focus groups were held with 35 participants. Four key inter‐related themes were identified: early and sustained engagement with key stakeholders; good planning but remaining flexible; managing the burden of practice change; and adopting and sustaining practice change. These themes capture and highlight the complexity and the challenges associated with implementation of the practice change across contexts and the project timeline.ConclusionIt is imperative to understand the challenges associated with complex practice change and ways in which implementation can be optimised. This study identified barriers and enablers experienced by staff implementing the bundled intervention. The themes encapsulate factors central to success of practice change within the complex, multilayered healthcare environment.Relevance to clinical practiceKey challenges highlight the need for forward planning, strategic engagement of key players, continuing monitoring and feedback together with adequate resourcing tailored to result in sustainable normalisation of the intervention over time. The COREQ checklist for qualitative studies has been used in reporting this study.
Identifying the experiences of new graduate nurses during the transition period to practice as a professional nurse
Authors: Salem Alghamdi Musaad , Ghazi Baker Omar 
Published: May 2020

AbstractAims and ObjectivesTo assess the impact of orientation programmes on new graduate nurses’ transition periods.BackgroundThe transition of graduate nurses from students to the practising professional nurse is often found to be stressful.DesignThe study has employed a descriptive correlational design.MethodsThe data were collected from 95 participants who were working as registered nurses in public hospitals in Al‐Bahah region. Questionnaire was used for collecting data which was based on the Casey‐Fink graduate nurse experience survey. SPSS software was used to analyse the results. The methods of this study are in line with the STROBE checklist.ResultsThe findings indicated statistically significant relationship between preceptor's support and communication leadership, professional satisfaction and job satisfaction, whereas an insignificant relationship was observed between preceptor's support and organising patient safety. The results also indicated that new graduate nurses were uncomfortable while performing different procedures/skills independently.ConclusionThe study implied instigation of the structured orientation programme to overcome the challenges faced by the new graduate nurses in their transition period.Relevance to clinical practiceThe upsurge in the nurses’ demand across Saudi Arabia makes this study highly relevant. It helps in optimising the transition experience of the nurses who are required to provide service in the acute sector.
Longitudinal Disconnection Tractograms to Investigate the Functional Consequences of White Matter Damage: An Automated Pipeline
Authors: Jordan Kesshi M. , Keshavan Anisha , Caverzasi Eduardo , Osorio Joseph , Papinutto Nico , Amirbekian Bagrat , Berger Mitchel S. , Henry Roland G. 
Published: May 2020

ABSTRACTBACKGROUND AND PURPOSENeurosurgical resection is one of the few opportunities researchers have to image the human brain pre‐ and postfocal damage. A major challenge associated with brains undergoing surgical resection is that they often do not fit brain templates most image‐processing methodologies are based on. Manual intervention is required to reconcile the pathology, requiring time investment and introducing reproducibility concerns, and extreme cases must be excluded.METHODSWe propose an automatic longitudinal pipeline based on High Angular Resolution Diffusion Imaging acquisitions to facilitate a Pathway Lesion Symptom Mapping analysis relating focal white matter injury to functional deficits. This two‐part approach includes (i) automatic segmentation of focal white matter injury from anisotropic power differences, and (ii) modeling disconnection using tractography on the single‐subject level, which specifically identifies the disconnections associated with focal white matter damage.RESULTSThe advantages of this approach stem from (1) objective and automatic lesion segmentation and tractogram generation, (2) objective and precise segmentation of affected tissue likely to be associated with damage to long‐range white matter pathways (defined by anisotropic power), (3) good performance even in the cases of anatomical distortions by use of nonlinear tensor‐based registration, which aligns images using an approach sensitive to white matter microstructure.CONCLUSIONSMapping a system as variable and complex as the human brain requires sample sizes much larger than the current technology can support. This pipeline can be used to execute large‐scale, sufficiently powered analyses by meeting the need for an automatic approach to objectively quantify white matter disconnection.
Public knowledge about dosage forms, routes of drug administration and medication proper storage conditions in Riyadh District, Saudi Arabia
Authors: Hailat Mohammad , Al-Shdefat Ramadan I , Muflih Suhaib M , Ahmed Nehad , Attarabeen Omar , Alkhateeb Fadi M , Al Meanazel Osaid , Gassar Ezeddin Salem 
Published: May 2020

Abstract

Objectives
The purpose of this study was to assess public knowledge on the safety, efficacy, proper storage conditions and other physiochemical properties of different dosage forms.

Methods
This study was based on a cross-sectional design. A structured quantitative survey, which included five sections, was used as an instrument for data collection. The first section addressed the demographic characteristics of the sample, whereas the second section assessed public knowledge on medications. The third section inquired about participants’ preferred dosage forms. The fourth section was related to the perceived effects of physiochemical properties of medicines on their safety and efficacy. The fifth section addressed participants’ thoughts on appropriate ways for medications usage and storage. A total of 752 participants completed the questionnaire. Data were analysed using SPSS (20.0) software.

Key findings
Although our study findings pointed out some knowledge gaps based on participants’ answers, most of the participants (87%) reported that physicians or pharmacists were the main sources of their medicine-related information. There was a great variation in participants’ responses regarding perceived onset of action, proper storage conditions and other properties of different dosage forms.

Conclusion
The study findings demonstrated the need to educate the public about basic information related to different dosage forms of medications.
Infant feeding beliefs and practices: Effects of maternal personal characteristics
Authors: Bushaw Andrea , Lutenbacher Melanie , Karp Sharon , Dietrich Mary , Graf Michelle 
Published: May 2020

AbstractPurposeInformation is limited about how mothers make food decisions on behalf of their children. Eating practices are established early in life and are difficult to change, so it is imperative to focus on the caregiver who influences a young child's food preferences and eating behaviors. The purpose of this secondary data analysis was to examine the relationship between maternal characteristics and infant feeding beliefs and practices in a sample of multiparous mothers with a history of a prior preterm infant birth.Design and MethodsSecondary analysis of a subset of data (n = 112) collected from women who participated in a randomized clinical trial (RCT) assessing the efficacy of a home‐based intervention to improve maternal and child outcomes. Inclusion criteria for the RCT: women ≥18 years of age at enrollment with a prior preterm live birth >20 and <37 weeks gestation, <24 weeks gestation at enrollment, spoke/read English, and received prenatal care at a regional medical center. Criteria for the subset included: completed the Infant Feeding Questionnaire at 5 months postpartum and had reported a prenatal body mass index (BMI). Univariate correlations and multiple linear regression analyses were used to assess the associations between maternal personal characteristics and infant feeding practices.ResultsMedian age of the mothers was 27 years (interquartile range [IQR]: 23–32) with median education of 12 years (IQR: 12–16). More than two‐thirds (68%) of the women breastfed their last baby. These women were less likely to be concerned about their infant's hunger (r = −.20; p = .035). After controlling for education, maternal BMI, breastfed last baby, self‐esteem, locus of control, and depressive symptoms, decreased maternal age (β = −.35; p < .001) and higher levels of stress (β = .19; p = .042) were associated with greater concern about their infant's hunger. Maternal demographic and psychosocial variables were not found to be statistically significantly associated with either concern about infant overeating and becoming overweight or an awareness of infant's hunger and satiety cues.Practice ImplicationsDifferences in maternal psychosocial variables and attitudes toward infant feeding may contribute to long term eating habits and weight outcomes in children. A better understanding of maternal variables that influence infant feeding attitudes and practices could improve the design of future intervention studies aimed at mothers at risk for having poor infant feeding practices.
Natural food mastication capability in preschool children according to their oral condition: A preliminary study
Authors: Linas Natacha , Peyron Marie‐Agnès , Eschevins Caroline , Hennequin Martine , Nicolas Emmanuel , Collado Valérie 
Published: May 2020

AbstractThis study investigated, for the first time, the masticatory capability of preschool children using natural foods, and the impact of an early oral health alteration (early childhood caries: ECC) on the granulometry of ready‐to‐swallow food boluses. Thirteen children with ECC were compared to 13 preschool children with a healthy oral condition. Oral health criteria and NOT‐S scores (Nordic Orofacial dysfunction Test‐Screening) were recorded. For each child, number of masticatory cycles (Nc), chewing time (Ti), and frequency (Fq = Nc/Ti) were recorded during mastication of raw carrot (CAR), cheese (CHS) and breakfast cereals (CER) samples. Food boluses were collected by stopping children at their food‐dependent individual swallowing threshold (Nc), and the median food bolus particle size value (D50) was calculated. Correlations were sought between oral health and masticatory criteria. In the ECC group, mean Fq values were significantly decreased for all three foods (p ≤ .001) and mean D50 values were significantly increased (p ≤ .001) compared to the control group (i.e., D50 CAR = 4,384 μm ± 929 vs. 2,960 μm ± 627). These alterations were related to the extent of ECC. The NOT‐S mean global score was significantly increased in children with ECC (2.62 ± 1.37 vs. 1 ± 0.91 in the control group, p ≤ .01), due to “Mastication and swallowing” domain impairment. This study gives granulometric normative values for three foods in preschool children and shows the impact of ECC on D50 values. The progression of children's masticatory capability after dental treatment, and the impact of such modifications of sensory input on future eating habits should be explored.
Pharmacokinetics of multivesicular liposomal encapsulated cytarabine when administered subcutaneously in dogs
Authors: Vazquez Fuster Irene B. , Taylor Amanda R. , Smith Annette N. , Duran Sue H. , Ravis William R. , Jasper Shanese L. , Arnold Robert D. 
Published: May 2020

AbstractBackgroundProlonged cytotoxic concentrations of cytarabine (CA) are required for maximum cytotoxicity. DepoCyt is a human liposomal cytarabine (LC) product that lasts longer in plasma and CSF compared with free CA (FC). The use of LC has not been evaluated in dogs.ObjectivesTo perform a LC pharmacokinetic (PK) study when administered SC in dogs.AnimalsFive healthy female beagles.MethodsThree‐period, 3‐treatment, nonblinded, randomized, and crossover design, including a pilot study. LC was administered at 50 mg/m2 SC and FC was administered at 25 and 50 mg/m2 SC and IV. Plasma CA concentrations were measured until 240, 72, and 8 hours after SC LC, SC FC, and IV FC administration, respectively. CA plasma concentrations were quantitated by ultra‐high‐performance liquid chromatography with mass spectrometry (MS/MS) detection and concentration‐time profiles were evaluated by noncompartmental analysis.ResultsSubcutaneous LC administration resulted in a maximum plasma concentration of 26.3 to 59.78 ng/mL, time to reach maximum plasma concentration of 2 hours, area under the concentration‐time curve to last measurable concentration of 669.3 to 1126 h × ng/mL, and plasma bioavailability (%F) of 19.6% to 31.3%. The PK profiles of FC after SC and IV administration differed when compared with LC.Conclusions and Clinical ImportanceIn healthy dogs, SC LC administration at 50 mg/m2 results in measurable plasma CA concentrations, is apparently safe and well tolerated, but does not result in prolonged cytotoxic plasma concentrations. Poor absorption of LC prevented establishment of a complete LC PK profile.
New measurement technique for characterizing small extraterrestrial materials by X‐ray diffraction using the Gandolfi attachment
Authors: Imae Naoya , Kimura Makoto 
Published: May 2020

AbstractIdentification and characterization of small extraterrestrial samples, such as small Antarctic meteorites <~1 cm, require the development of convenient laboratory‐based nondestructive analytical techniques using X‐ray diffraction (XRD). We explore the characterization criteria using an X‐ray diffractometer with a Gandolfi attachment using sub‐mm small fragments and powder aggregates for various kinds of stony meteorites and develop a new analytical technique. We primarily focus on olivine and pyroxene because they are the most abundant and important minerals for stony meteorite classification. A new calibration is performed to estimate the FeO content of the olivine in unequilibrated ordinary chondrites, which is useful for determining the meteorite chemical group irrespective of powder aggregate diameter but dependent on fragment grain diameter. This is because X‐ray intensity absorption is more effective for grains than for powders. Clinoenstatite (Cen) and orthoenstatite (Oen) were distinguished using the presence or absence of the isolated Oen 511 index peak. The method is also applied to other stony meteorites including carbonaceous chondrites and achondrites. The XRD results are consistent with studies based on polished sections involving textural observations by scanning microscope and chemical compositions of the constituent minerals. The new measurement technique presented here is convenient because of its use in air by the laboratory‐based X‐ray diffractometer, which makes it useful for the initial analyses of restricted extraterrestrial sample characterization.
The gender ideology of ‘Wise Mother and Good Wife’ and Korean immigrant women’s adjustment in the United States
Authors: Seo You Jung , Cheah Charissa S. L. , Cho Hyun Su 
Published: May 2020

AbstractThe notion of ‘wise mother and good wife (WMGW)’ (Hyonmo Yangcho) is the traditional idealized image of Korean womanhood as one who serves her country and others through her roles as a mother and wife. This ideology may continue to have some significance in the lives of many first‐generation Korean immigrant women, but its potential role in the adjustment challenges these women may face while acculturating to the immigrant context in the United States has received little attention. In this paper, we briefly review the historical background of the WMGW ideology and discussed the significance of focusing research attention on the role of this notion in contemporary first‐generation Korean immigrant women in the United States. We focus on the intersecting influences of gender, ethnicity, and immigrants’ generation status, which may further marginalize some first‐generation Korean immigrant mothers. We then outline possible unique challenges faced by some of these mothers due to the WMGW gender ideology, highlighting potential immigration‐related difficulties including changes in their social support networks, parenting burden, mental health, and language issues. Finally, we provide suggestions for researchers and practitioners working with U.S. Korean immigrant women.
Ultrasound‐Guided Hydrodilatation of the Shoulder Capsule at the Rotator Interval: Technical Tips and Tricks
Authors: Ricci Vincenzo , Chang Ke‐Vin , Özçakar Levent 
Published: May 2020

AbstractAdhesive capsulitis and disorders of the intra‐articular portion of the long head of the biceps brachii tendon are common causes of shoulder pain. Sonographic findings, coupled with clinical evaluation and medical history, are paramount for prompt diagnosis. Herewith, either to precisely confirm the pain generator(s) or to appropriately treat relevant cases, ultrasound‐guided interventions are often required in daily clinical practice. Targeting the anatomical structures involved in the aforementioned pathological conditions, we briefly describe some technical tips and tricks as regards ultrasound‐guided hydrodilatation of the shoulder capsule at the rotator interval.
Cell wall remodeling under salt stress: Insights into changes in polysaccharides, feruloylation, lignification, and phenolic metabolism in maize
Authors: Oliveira Dyoni M. , Mota Thatiane R. , Salatta Fábio V. , Sinzker Renata C. , Končitíková Radka , Kopečný David , Simister Rachael , Silva Mariana , Goeminne Geert , Morreel Kris , Rencoret Jorge , Gutiérrez Ana , Tryfona Theodora , Marchiosi Rogério , Dupree Paul , del Río José C. , Boerjan Wout , McQueen‐Mason Simon J. , Gomez Leonardo D. , Ferrarese‐Filho Osvaldo , dos Santos Wanderley D. 
Published: May 2020

AbstractAlthough cell wall polymers play important roles in the tolerance of plants to abiotic stress, the effects of salinity on cell wall composition and metabolism in grasses remain largely unexplored. Here, we conducted an in‐depth study of changes in cell wall composition and phenolic metabolism induced upon salinity in maize seedlings and plants. Cell wall characterization revealed that salt stress modulated the deposition of cellulose, matrix polysaccharides and lignin in seedling roots, plant roots and stems. The extraction and analysis of arabinoxylans by size‐exclusion chromatography, 2D‐NMR spectroscopy and carbohydrate gel electrophoresis showed a reduction of arabinoxylan content in salt‐stressed roots. Saponification and mild acid hydrolysis revealed that salinity also reduced the feruloylation of arabinoxylans in roots of seedlings and plants. Determination of lignin content and composition by nitrobenzene oxidation and 2D‐NMR confirmed the increased incorporation of syringyl units in lignin of maize roots. Salt stress also induced the expression of genes and the activity of enzymes enrolled in phenylpropanoid biosynthesis. The UHPLC–MS‐based metabolite profiling confirmed the modulation of phenolic profiling by salinity and the accumulation of ferulate and its derivatives 3‐ and 4‐O‐feruloyl quinate. In conclusion, we present a model for explaining cell wall remodeling in response to salinity.
You get me: Examining the implications of couples’ depersonalization agreement for employee recovery
Authors: Wilson Kelly Schwind , Kleshinski Catherine E. , Matta Fadel K. 
Published: May 2020

AbstractPrevious research demonstrates that depersonalization is harmful for employee outcomes. In addition, research is beginning to examine employees’ family context along with their experiences both at work and at home. We advance these literatures using shared reality theory as a foundation for investigating couples’ dyadic agreement surrounding employee depersonalization and its implications. Using polynomial regression and response surface methodology of data from employee‐significant other dyads, in Study 1, we find that agreement between partners on employee depersonalization is associated with lower work‐to‐family conflict (following general shared reality theory arguments) and increased subsequent recovery for the employee. In Study 2, we examine more specific shared reality theory arguments using the same analytic approach. We show that agreement between partners on employee depersonalization is associated with less distress and an increased perception that one's depersonalization is understood, and ultimately increased recovery for the employee via reductions in distress. Taken together, these results suggest the harmful effects of depersonalization are largely minimized if an employee's partner accurately recognizes their depersonalization. Interestingly, our collective results show it is better for employees to have agreement with their partners surrounding a high level of employee depersonalization than have low levels of depersonalization accompanied by disagreement.
The Use of Sampling Weights inM-Quantile Random-Effects Regression: An Application to Programme for International Student Assessment Mathematics Scores
Authors: Spagnolo Francesco Schirripa , Salvati Nicola , D’Agostino Antonella , Nicaise Ides 
Published: May 2020

SummaryM-quantile random-effects regression represents an interesting approach for modelling multilevel data when the researcher is focused on conditional quantiles. When data are obtained from complex survey designs, sampling weights must be incorporated in the analysis. A robust pseudolikelihood approach for accommodating sampling weights in M-quantile random-effects regression is presented. In particular, the method is based on a robustification of the estimating equations. The methodology proposed is applied to the Italian sample of the Programme for International Student Assessment 2015 survey to study the gender gap in mathematics at various quantiles of the conditional distribution. The findings offer a possible explanation of the low proportion of women in science, technology, engineering and mathematics sectors.