bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding the impact of a collective leadership intervention on team working and safety culture in healthcare teams: a realist evaluation protocol
Authors: De Brun Aoife , Rogers Lisa , O'Shea Marie , McAuliffe Eilish 
Published: March 2020

There is accumulating evidence for the value of collective and shared approaches to leadership across sectors and settings. However, relatively little research has explored collective leadership in healthcare and thus, there is little understanding of what works for healthcare teams, why, how and to what extent. This study describes the approach that will be adopted to the realist evaluation of a collective leadership intervention with four heterogenous healthcare teams in four different settings. A realist evaluation will be conducted. Realist evaluation is a theory-based approach to evaluation. It enables the use of mixed-methods to explore the research question of interest. Development of an initial programme theory (IPT) constitutes the first phase of the approach. This IPT will be informed by interviews with members of teams identified as working collectively, an examination of extant literature using realist synthesis, and will be refined through consultation with an expert panel. A multiple case study design will be adopted to explore the impact of the intervention, including quantitative scales on teamworking, leadership and safety culture, realist interviews with key informants and observations of teams during intervention sessions. Analysis of data will be guided by the IPT to refine the theory and context-mechanism-outcome configurations. Findings from the cases will be compared to identify patterns or demi-regularities and to explore if the intervention operates differently in different contexts. This analysis and synthesis of findings across the teams will inform the development of a middle range theory that will not only add to our understanding of how collective leadership influences teamwork and patient safety, but also provide guidance for future collective leadership interventions. Favourable ethical opinion has been received from the University College Dublin Ethics Committee. Results will be disseminated via publication in peer-review journals, national and international conferences and to stakeholders/interest groups.
FILOSOFIA, MEDICINA E CUIDADO DO CORPO NO BANQUETE DE PLATÃO
Authors: Da Silva Felipe Gustavo Soares 
Published: March 2020

O presente trabalho tem como objetivo demonstrar a presença da relação filosofia e medicina na obra O Banquete, de Platão, através da leitura do discurso do médico Erixímaco, notadamente marcado pelo conceito de amor (Ἔρως) e de harmonia (αρμονία) em relação ao corpo. A contribuição de Platão em seu Banquete é de reforçar a importância do cuidado com o corpo nas práticas de cuidado de si na antiguidade.
Gestaltung und Erprobung einer Virtual-Reality-Anwendung zur Unterstützung des Prototypings in Design-Thinking-Prozessen
Authors: Vogel Jannis , Schuir Julian , Thomas Oliver , Teuteberg Frank 
Published: March 2020

ZusammenfassungUm in zunehmend komplexen und wettbewerbsintensiven Märkten konkurrenzfähig bleiben zu können, muss die Innovationskraft eines Unternehmens sichergestellt werden. Dabei kommt dem Menschen und seiner Kreativität eine zentrale Rolle zu. Design Thinking bietet ein Methodenspektrum, um die Kreativität von Einzelnen in einem gruppendynamischen, benutzerzentrierten Prozess in Innovationen zu überführen. Es kommen insbesondere spielerische Ansätze zur Kreativitätsförderung zum Einsatz, zu denen beispielsweise das Lego-Prototyping gehört. Digitale Unterstützungswerkzeuge sind bisher selten, obwohl sowohl Forschung als auch Praxis die virtuelle Realität aufgrund ihres immersiven Charakters zunehmend als ein Kreativitätsmedium betrachten. Im vorliegenden Beitrag wird daher eine Virtual-Reality-Anwendung zur Unterstützung des Prototypings in Design-Thinking-Prozessen als ein Proof of Concept vorgestellt und im Rahmen einer Case-Study evaluiert. Im Ergebnis resultiert eine Virtual-Reality-Umgebung, die einen positiven Effekt auf das Design-Thinking-Prototyping hinsichtlich der Kreativitätsförderung, der Effizienz und der Intuition hat. Hervorgehend aus den Evaluationsergebnissen entstehen Ansätze für eine folgende Iteration sowie Handlungsempfehlungen für die Gestaltung und den Einsatz unternehmensbezogener VR-Anwendungen. Perspektivisch gesehen eröffnen VR-Anwendungen neue Potenziale zur Gestaltung von digitalisierten Arbeitswelten.
PRODUCTION AND ANALYSIS OF THE COMPOSITION OF SUPERCRITICAL CARBON DIOXIDE EXTRACTS FROM EXOCARPY CITRUS MEYERI TAN.
Authors: Molokhova Yelena Igorevna , Ponomareva Yekaterina Ivanovna , Kudinov Andrey Viktorovich 
Published: March 2020

The purpose of this work is to evaluate the effectiveness of using supercritical carbon dioxide extraction to obtain essential oils from exocarpy of Meyer lemon in comparison with the pressing method.
The plant material is represented by the exocarpy of Meyer lemon Citrus meyeri Tan., Rutovye family – Rutaceae, collected in the vicinity of Khujand (Republic of Tajikistan), in November 2014. Supercritical carbon dioxide extracts (CO2 extracts) were obtained at the Research Center for Ecological GORO resources (Rostov-on-Don) at the KOERS1 installation. As a comparison, we used the essential oil obtained by direct pressing on hydraulic presses without heating. Qualitative and quantitative analysis of the components was carried out by gas chromatography with chromatography-mass spectrometric detection.
As a result of the study, it was found that the optimal parameters of CO2 extraction, which provide the highest content of limonene and γ-terpinene in the extract, are: 50 °С, 16 MPa, and 30 min. A comparative analysis of the content of extract components showed that the yield of limonene during supercritical extraction, compared with traditional technology, increased by 7.5%, the γ-terpinene content was 1.5 times. In addition, significant differences were found in the qualitative and quantitative composition of the essential oil and the CO2 extract of Meyer lemon. In essential oil, the content is higher: α- and β-pinene, p-cumene, geranial, and others. In the CO2 extract, the content is higher: sabinene, α-humulene, β-bisabolene and other low-volatile compounds, with an additional 9 components: α-thuen, terpenolene, geranyl acetate, etc., which indicates the need for an additional pharmacological study of the CO2-extract of Meyer lemon.
CONTENT OF VITAMIN C IN BERRIES OF THE GRAPES CULTIVATED IN THE CONDITIONS OF THE SOUTH OF WESTERN SIBERIA
Authors: Borodulina Irina Dmitriyevna , Vorotyntseva Mariya Vasil'yevna , Makarova Galina Aleksandrovna , Zemtsova Anna Yakovlevna , Sokolova Galina Gennad'yevna 
Published: March 2020

Grapes is a highly valuable food product due to the presence in it of a number of biologically active substances, among which vitamins occupy a special place. One of the most important and studied in grapes is vitamin C (ascorbic acid). The ascorbic acid contained in plant tissue participates in redox metabolism, thereby increasing the resistance of plant organisms to infections and low negative temperatures. Studies aimed at determining the concentration of vitamin C in plant material are important both for breeding and for identifying the most sustainable competitive varieties.
The purpose of these studies is to study the content of vitamin C in grapes cultivated in the South of Western Siberia. Conducted research with 12 introduced varieties and selected forms growing in the collection of the Research Institute of horticulture of Siberia M.A. Lisavenko, allowed to establish dependence of accumulation of ascorbic acid in berries on weather conditions; to allocate 5 genotypes with high content of vitamin C. It is noted that the ripening period of berries, their color, as well as the direction of use and ecological and geographical origin of varieties and selected forms did not affect the accumulation of vitamin C in the period 2014–2016.
ACTIVE CARBONS, OBTAINED BY THERMOCHEMICAL ACTIVATION OF RAPE STRAW
Authors: Khviyuzova Kristina Aleksandrovna , Bogdanovich Николай Иванович , Voropayeva Nadezhda Leonidovna , Karpachev Vladimir Vladimirovich 
Published: March 2020

The presence of a huge amount of waste of plant origin, including annually renewable, is a high innovative resource for obtaining a variety of useful products of large and small-tonnage chemistry. Processing straw of agricultural crops into activated carbons (AC), which are successfully used in various industries and agriculture, is one of the possible directions of using agricultural waste (AIC) to obtain new functional materials with specific properties. The paper presents studies on the physicochemical properties and structural characteristics of activated carbons based on rape straw and discusses the prospects of their application for solving the most important problems of the agricultural sector. The effect of thermochemical activation temperature (650–750 °С) on the characteristics of the porous structure of adsorbents was studied. The characteristics are calculated on the basis of isotherms of low-temperature (77 K) nitrogen adsorption-desorption. Temperature dependences of the specific surface area, total pore volume, and micropore volume were obtained. It was found that KOH promotes surface development and the formation of a porous system in the entire temperature range.
RESEARCH OF THE CONTENT OF PHENOLS, FLAVONOIDS, ANTIOXIDANT FORCE, AND ANTI-RADICAL AC-TIVITY OF SALVIA TESQUICOLA SAGE LEAVES (FAMILY CRYSTAL)
Authors: Makarova Nadezhda Viktorovna , Valiulina Dinara Fanisovna , Kirushina Viktoriya Aleksandrovna 
Published: March 2020

In the course of the work, the content of phenols, flavonoids, antiradical activity and antioxidant power were studied for extracts of sage leaves of the genus Salvia tesquicola (of the Clear-colored family), obtained by traditional infusion methods and using innovative technologies – microwave radiation and ultrasonic processing. It was found that the highest content of phenols and flavonoids was observed during the treatment of aqueous extracts of sage leaves with ultrasonic radiation for 1.5 hours – 1056 mg (HA)/100 g and 346 mg (K) /100 g, respectively. The highest content of dry substances is observed when treating aqueous extracts of sage leaves with ultrasonic radiation (15.32%). Summarizing the data on the three studied parameters, the solids content, the total content of phenols and flavonoids, we can recommend the use of ultrasonic treatment as a factor that increases the content of the studied substances in extracts of sage leaves Salvia tesquicola.
The lowest antiradical activity was observed in aqueous extracts of sage leaves, obtained at 37 °C for 2 hours (3.6 mg/ml). The maximum value of antioxidant strength according to the FRAP method was revealed when obtaining aqueous extracts of sage leaves using ultrasonic radiation at 37 °C for 1.5 h – 24.30 mmol Fe2+/1 kg of the feedstock. Analysis of the data obtained from all studied parameters in the study of concentrated extracts of sage leaves, showed slight differences compared with those obtained in the study of aqueous extracts of sage leaves, namely: the content of phenols - 347 mg (HA)/100 g, the content of flavonoids – 387 mg (K)/ 100 g, contains Contents solids - 38.52%, antiradical activity - 2.4 mg /ml, the antioxidant power of FRAP method – 9.99 mmol Fe2+/1 kg of feedstock.
SWIRL STAGES FOR HEAT AND MASS EXCHANGE EQUIPMENT
Authors: Bogatkova Anastasiya Viktorovna , Frolov Aleksandr Sergeyevich , Zemtsov Denis Andreyevich , Zhukova Ol'ga Petrovna , Voynov Nikolay Aleksandrovich 
Published: March 2020

The results of experimental studies of hydrodynamics and mass exchange at vortex stages in bubbling mode are presented, as well as data of numerical simulation by finite element method using models of k-ε This made it possible to establish the presence of circulation movement of liquid at the stage, to determine profiles of phase speeds, to obtain the value of initial speed of gas phase movement, at which coordination of experimental and design values of liquid speed is observed. The design method shows the effect of the cylindrical partition installed between the swirler and the stage wall on the fluid velocity profile and its distribution in the working volume. It is proposed to use the obtained results of numerical modeling when designing multi-element stages to provide the required hydrodynamics on it.
New vortex contact devices with annular channels, having lower hydraulic resistance compared to tangential devices and providing a developed interfacial surface, stable without fluctuations, operation of the stage at high gas and liquid flow rates, have been investigated.
Data are presented for determination of hydraulic resistance of vortex stage, value of interfacial surface, coefficients of mass output and efficiency in investigated range of loads of liquid and gas L/G = 10-150.
Designs of vortex contact stages for industrial brew column have been developed. Contact devices with ring channels allow to bring dissipation of energy in a gas phase in the bubbling and ring mode to 5 W/kg, to increase an interphase surface to 2000 m-1 and to reach the size of superficial coefficient of a massotdacha about (0.5-0.8)·10-3 of m/s.
INVESTIGATION OF THE PROCESS OF GELATION OF GALACTOMANNAN ISOLATED FROM THE SEEDS OF STYPHNOLOBIUM JAPONICUM (FABACEAE)
Authors: Filatova Al'bina Vasil'yevna , Azimova Luiza Bakhtiyarovna , Turaev Abbaskhan Sabirkhanovich 
Published: March 2020

This article is devoted to the study of the structuring of galactomannan isolated from Sophora japonica with borate ions. Based on the galactomannan isolated from the seeds of Sophora japonica (lat. Styphnolobium japonicum), a basis for a soft dosage form has been developed. It has been suggested that the network structures of gel systems are formed due to the formation of bridge bonds between the functional groups of the galactomannan and boron ions. Studied the rheological properties of the resulting jelly. The study of the process of gelation of galactomannan showed that the dynamic viscosity depends on the pH, the concentration of the crosslinking agent and the concentration of the solution of galactomannan. The gel was plasticized and it was assumed that the presence of glycerol destroys chemical crosslinking, due to the formation of a complex compound with sodium tetraborate. A soft dosage form has been developed with the addition of 10% propylene glycol as a plasticizer and a preservative solution – 0.1%. As a result of further research developed soft dosage forms revealed that after 6–12 months of storage in vivo at a temperature of +20±5 °C, the studied gel remained stable. These studies made it possible to apply the studied gel in medicine as the basis for a soft dosage form.
The possible protective role of green tea extract on the intestinal mucosal changes induced by fluoride on adult albino rats
Authors: M. Abo El Wafa Ssahar , Abdel-Mohsen Abdel-Aziz Eman , M. Shawky Lamiaa , S. Zaki Mariam 
Published: March 2020

Background: Fluoride is an inorganic element present everywhere in the environment and has cumulative toxic effects from prolonged ingestion. Green tea used since ancient times as a medical drink due to its multiple health benefits owing to its anti-oxidative and anti-apoptotic activities. Aim: To the best of our knowledge there were no studies until now concerning the possible protective role of green tea extract on the intestinal mucosal changes induced by fluoride on adult albino rats, so this work tried to investigate this role. Materials and Methods: Forty male adult albino rats randomly and equally divided into four groups, Group I: received distilled water only orally via a gastric tube. Group II: received green tea extract (GTE) 150 mg/kg dissolved in distilled water and freshly prepared for 35 days. Group III: received sodium fluoride (NaF) once daily oral dose of 10 mg/kg dissolved in distilled water for 35 days. Group IV: received NaF in the same dose as group III concomitant with GTE as the previously adjusted dose for 35 days. Body weight of all the studied groups was recorded at the start and after 35 days from the beginning of this study. After that the study tested the antioxidant and oxidant parameters in intestinal tissue as MDA, reduced GSH, and CAT, histopathological and immunohistochemical examination of intestinal tissue using PCNA marker were also included. Results: the rate of weight gain was little in NaF group compared to other groups. Concomitant administration of GTE with NaF resulted in highly significant decrease in MDA level, highly significant increase in reduced GSH level and highly significant elevation in CAT level when compared with NaF group. Many of abnormalities as moderate increase in goblet cell mass and highly expression of PCNA stain in a form of brown nuclear coloration were detected in intestinal tissues in NaF group by histopathological and immunohistochemical study that improved with administration of GTE. Conclusion: concomitant administration of GTE was improved the biochemical, histopathological and immunohistochemical alterations in intestinal mucosa that treated with NaF.Â Â Â
The potential beneficial effect of exenatide on cisplatin induced nephrotoxicity in non-diabetic rats
Authors: Abdel-Mohsen Abdel-Aziz Eman , M. Abo El Wafa Sahar 
Published: March 2020

Background: Cisplatin is a major antitumor drug used for treatment of solid tumors. Nephrotoxicity is its main limiting side effect. Exenatide is described as an incretin mimetic polypeptide, it acts as a GLP-1 receptor agonist and its insulinotropic activity is mediated through binding to and stimulation of GLP-1 receptors on human pancreatic Î²-cells. Aim: the present work was designed to study the effect of exenatide on experimentally cisplatin induced nephropathy in non- diabetic rats. Materials and Methods: Thirty two male adult Sprague Dawley rats randomly divided into four groups, each consisted of 8 animals, and distributed as follows: Group I: (control) normal group and received saline vehicle. Group II: (cisplatin) group includes rats injected intraperitoneally by a single dose of cisplatin (6 mg/kg) to induce nephrotoxicity, received no treatment and were sacrificed 7 days after cisplatin administration. Group III: (exenatide) group: rats treated by exenatide (10 mg/kg/day s.c.) for 4 weeks. Group IV: (exenatide+cisplatin) group: rats treated by exenatide (10 mg/kg/day s.c.) for 4 weeks before induction of nephrotoxicity by cisplatin. The following parameters were measured: fasting blood glucose, serum urea, serum creatinine, reduced glutathion (GSH) level in the renal tissue, tumor necrosis factor-Î± (TNF-Î±) level in the renal tissue, renal blood flow changes and histopathological changes of the kidney. Results: Pretreatment with exenatide resulted in significant reduction in serum urea, serum creatinine level and renal TNF- Î± level compared to cisplatin group but still significantly higher than control group with significant increase in renal GSH level and renal blood flow compared to cisplatin group but still also significantly lower than control group. Cisplatin group showing tubular degeneration with infiltration of inflammatory cells while pretreatment with exenatide showing certain improvement in general histological structure with mild tubular degeneration and less inflammatory cell infiltration. Conclusion: it can be concluded that the use of exenatide improved the biochemical and histopathological changes that occur in the renal tissue by cisplatin.Â Â
Realtime index-free single source SimRank processing on web-scale graphs
Authors: Shi Jieming , Jin Tianyuan , Yang Renchi , Xiao Xiaokui , Yang Yin 
Published: March 2020

Given a graph G and a node u ∈ G, a single source SimRank query evaluates the similarity between u and every node v ∈ G. Existing approaches to single source SimRank computation incur either long query response time, or expensive pre-computation, which needs to be performed again whenever the graph G changes. Consequently, to our knowledge none of them is ideal for scenarios in which (i) query processing must be done in realtime, and (ii) the underlying graph G is massive, with frequent updates.
Motivated by this, we propose SimPush, a novel algorithm that answers single source SimRank queries without any pre-computation, and achieves significantly higher query speed than even the fastest known index-based solutions. Further, SimPush provides rigorous result quality guarantees, and its high performance does not rely on any strong assumption of the graph. Specifically, compared to existing methods, SimPush employs a radically different algorithmic design that focuses on (i) identifying a small number of nodes relevant to the query, and subsequently (ii) computing statistics and performing residue push from these nodes only.
We prove the correctness of SimPush, analyze its time complexity, and compare its asymptotic performance with that of existing methods. Meanwhile, we evaluate the practical performance of SimPush through extensive experiments on 9 real datasets. The results demonstrate that SimPush consistently outperforms all existing solutions, often by over an order of magnitude. In particular, on a commodity machine, SimPush answers a single source SimRank query on a web graph containing over 133 million nodes and 5.4 billion edges in under 62 milliseconds, with 0.00035 empirical error, while the fastest index-based competitor needs 1.18 seconds.
Sex Differences in Resistance Training: A Systematic Review and Meta-Analysis
Authors: Roberts Brandon M. , Nuckols Greg , Krieger James W. 
Published: March 2020

Abstract
Roberts, BM, Nuckols, G, and Krieger, JW. Sex differences in resistance training: A systematic review and meta-analysis. J Strength Cond Res 34(5): 1448–1460, 2020—The purpose of this study was to determine whether there are different responses to resistance training for strength or hypertrophy in young to middle-aged males and females using the same resistance training protocol. The protocol was pre-registered with PROSPERO (CRD42018094276). Meta-analyses were performed using robust variance random effects modeling for multilevel data structures, with adjustments for small samples using package robumeta in R. Statistical significance was set at P < 0.05. The analysis of hypertrophy comprised 12 outcomes from 10 studies with no significant difference between males and females (effect size [ES] = 0.07 ± 0.06; P = 0.31; I2 = 0). The analysis of upper-body strength comprised 19 outcomes from 17 studies with a significant effect favoring females (ES = -0.60 ± 0.16; P = 0.002; I2 = 72.1). The analysis of lower-body strength comprised 23 outcomes from 23 studies with no significant difference between sexes (ES = −0.21 ± 0.16; P = 0.20; I2 = 74.7). We found that males and females adapted to resistance training with similar effect sizes for hypertrophy and lower-body strength, but females had a larger effect for relative upper-body strength. Given the moderate effect size favoring females in the upper-body strength analysis, it is possible that untrained females display a higher capacity to increase upper-body strength than males. Further research is required to clarify why this difference occurs only in the upper body and whether the differences are due to neural, muscular, motor learning, or are an artifact of the short duration of studies included.