bluuebunny/crossref_metadata_2025_split huggingface dataset:
D
esulfofarcimen
Authors: Watanabe Miho , Fukui Manabu , Kuever Jan 
Published: March 2020

Abstract

De.sul.fo.far'ci.men. L. pref.
de
from; L. neut. n.
sulfur
sulfur; L. neut. n.
farcimen
sausage; N.L. neut. n.
Desulfofarcimen
a sausage‐shaped sulfate reducer.

Desulfotomaculota (Firmicutes_B) / Desulfotomaculia / Desulfotomaculales / Desulfofarciminaceae / Desulfofarcimen

Cells are straight or slightly curved rods. Gram‐stain‐negative. Spherical spores occur subterminal of cells causing swelling. Motile by means of a polar flagellum. Strictly anaerobic, having a respiratory type of metabolism. Mesophilic and neutrophilic. NaCl is not required for growth. Chemoorganoheterotroph using organic acids, short‐chain fatty acids, and alcohols. The substrates are oxidized to CO
2
via the anaerobic C
1
pathway (carbon monoxide dehydrogenase [CO‐DH] or Wood–Ljungdahl pathway) as indicated by genome data and enzymatic activity analysis. Biotin is required for growth. Sulfate and thiosulfate are used as electron acceptors and reduced to sulfide; fumarate, sulfite, and elemental sulfur are not utilized. Unable to ferment organic substances. Neither a
c
‐type cytochrome nor desulfoviridin is detected. The major cellular fatty acids are C
16 : 0
, C
16 :1
ω7
c
, and C
18 :1
ω7
c
. MK‐7 is the major menaquinone, and small amounts of MK‐6 are detected. Found in piggery waste in Göttingen, Germany.

DNA G + C content (mol%)
: 41.6 (genome).

Type species
:
Desulfofarcimen acetoxidans
Watanabe et al. 2018
VP
(basonym:
Desulfotomaculum acetoxidans
Widdel and Pfennig 1977, VL1).
G
eodermatophilales
Authors: Montero‐Calasanz Maria del Carmen 
Published: March 2020

Abstract

Ge.o.der.ma.to.phil.a'les. N.L. masc. n.
Geodermatophilus
type genus of the order; suff. ‐
ales
ending to denote order; N.L. fem. pl. n.
Geodermatophilales
the
Geodermatophilus
order.

Actinobacteria / Actinobacteria / Geodermatophilales

Cells are Gram‐positive, aerobic, have motile and nonmotile forms, mainly inhabit arid and degraded habitats but also marine and plant‐associated environments, and are pigmented. A representative of the class
Actinobacteria
. Contains two families,
Geodermatophilaceae
and
Antricoccaceae
. The type genus is
Geodermatophilus
.
Enantioselective Ammonium Ylide Mediated One‐Pot Synthesis of Highly Substituted γ‐Butyrolactones
Authors: Drennhaus Till , Öhler Laura , Djalali Saveh , Höfmann Svenja , Müller Clemens , Pietruszka Jörg , Worgull Dennis 
Published: March 2020

AbstractAn ammonium ylide mediated access towards trans‐β,γ‐disubstituted, all‐trans‐α,β,γ‐trisubstituted, and α,α,β,γ‐tetrasubstituted γ‐butyrolactones bearing a broad variety of functionalities was developed. Starting from widely accessible benzylidene Meldrum's acid derivatives and α‐bromo carbonyl compounds, γ‐butyrolactones were obtained in yields between 32–99% with up to excellent diastereoselectivities (>95:5) via a DABCO‐mediated [2+1] annulation. Utilization of enantiomerically pure cinchona alkaloid derivatives enables the first asymmetric ammonium ylide mediated method to provide (3R, 4R)‐β,γ‐disubstituted and (2R, 3R, 4R)‐α,β,γ‐trisubstituted γ‐butyrolactones in moderate to good yields with up to very good enantiomeric ratios (97:3). The scalability of the transformation was proven while determining the absolute configuration.magnified image
Resources for functional genomic studies of health and development in nonhuman primates
Authors: Jasinska Anna J. 
Published: March 2020

AbstractPrimates display a wide range of phenotypic variation underlaid by complex genetically regulated mechanisms. The links among DNA sequence, gene function, and phenotype have been of interest from an evolutionary perspective, to understand functional genome evolution and its phenotypic consequences, and from a biomedical perspective to understand the shared and human‐specific roots of health and disease. Progress in methods for characterizing genetic, transcriptomic, and DNA methylation (DNAm) variation is driving the rapid development of extensive omics resources, which are now increasingly available from humans as well as a growing number of nonhuman primates (NHPs). The fast growth of large‐scale genomic data is driving the emergence of integrated tools and databases, thus facilitating studies of gene functionality across primates. This review describes NHP genomic resources that can aid in exploration of how genes shape primate phenotypes. It focuses on the gene expression trajectories across development in different tissues, the identification of functional genetic variation (including variants deleterious for protein function and regulatory variants modulating gene expression), and DNAm profiles as an emerging tool to understand the process of aging. These resources enable comparative functional genomics approaches to identify species‐specific and primate‐shared gene functionalities associated with health and development.
Rolf Huisgen, Eminent Chemist and Polymath (1920–2020): In His Own Words and In His Publication Metrics
Authors: Seeman Jeffrey I. , Restrepo Guillermo 
Published: March 2020

AbstractAs a compliment to several other publications that present and honor Rolf Huisgen's research achievements, the first part of this paper reveals the human side of this eminent chemist. From excerpts from many of his personal and professional writings, Huisgen's personality and philosophies of life are revealed. Also revealed is Huisgen functioning as a historian of chemistry. The second part of this paper examines the scientometrics of Huisgen's publication history. In the late 1950s and early 1960s, Huisgen's career experienced a major transition in terms of publication metrics and the influence these papers had on the organic chemistry community. This was the result of his research into 1,3‐dipolar cycloadditions. Citations to his scientific contributions are well spread over many of his papers, demonstrating his constant work and the building up of a research topic, which continued after his official retirement in 1988. In fact, 17 % of his more than 600 publications appeared after 1988. The majority of Huisgen's papers were co‐authored with his many graduate and postdoctoral students. Consistent with the trend of that era, Huisgen was the sole author of most of his Review articles, and not just those of his many plenary lectures, and it is those Review articles that proved to be his most cited publications. This demonstrates the power and influence of Review articles—secondary sources, in the vocabulary of historians and sociologists of science. In those Review articles, Huisgen principally described the state of the art of 1,3‐dipolar cycloadditions—his golden offspring.
Structural Elucidation of Selective Solvatochromism in a Responsive‐at‐Metal Cyclometalated Platinum(II) Complex
Authors: Soto Miguel A. , Carta Veronica , Andrews Ryan J. , Chaudhry Mohammad T. , MacLachlan Mark. J. 
Published: March 2020

AbstractWe report the synthesis, characterization, and spectroscopic investigations of a new responsive‐at‐metal cyclometalated platinum(II) complex. With mild chemical oxidants and reductants, it was possible to obtain the same complex in three different oxidation states and each of these complexes was structurally characterized by single‐crystal X‐ray diffraction. We discovered that the platinum(II) complex displays strong solvatochromism in the solid state, which can be attributed to modulation of Pt⋅⋅⋅Pt interactions that results in switching between optical and photoluminescent states. Incorporating responsive‐at‐metal species as dynamic components in nanostructured materials might facilitate response amplification, sensing, actuation, or self‐healing processes.
Large‐scale geochemical survey by pXRF spectrometry of archaeological settlements and features: new perspectives on the method
Authors: Save Sabrina , Kovacik Joseph , Demarly‐Cresp Florence , Issenmann Régis , Poirier Sandy , Sedlbauer Simon , Teyssonneyre Yannick 
Published: March 2020

AbstractOver the past several decades the geochemical study of archaeological sediments has experienced an increase in interest from archaeologists in search of new methods to investigate spatial organization and space function. Used with other proxies like geophysics, archaeobotany and micromorphology, geochemistry provides a new insight into microscopic pollution generated by past human activities, and thus can explain or confirm the function of features and spaces. Portable X‐ray fluorescence (pXRF) spectrometry offers new perspectives to the archaeological community to test, develop and integrate geochemical surveys in the daily routine of fieldwork, especially in the developer‐funded archaeology sector. We have undertaken over 20 geochemical surveys using pXRF spectrometry, both in the field and on bulk samples, and from a wide variety of sites, sedimentological, and chronological contexts. Working exclusively on developer‐funded projects, we present a series of results detailing a range of chemical element associations, including details on how the data is organized spatially and how these data may be interpreted. For some associations, such as that between phosphorus, calcium and strontium, our work confirms and builds on existing studies. For other elements such as zirconium, or the association between potassium, chromium and vanadium, our work presents new data patterns as well as a series of new hypothesis; the interpretation of these patterns remains at an early stage and we hope that further work will be done to test and detail the origins of these chemical associations and enrichments, with the goal of confirming the human activities and/or natural processes from which they originated. The rapidity and cost‐efficiency of pXRF, especially when usedin situin the field, makes it the ideal method for documenting the geochemical characteristics of landscapes; the approach we have developed means that geochemical survey can become a regular part of archaeological practice.
Dry Skulls and Cone Beam Computed Tomography (CBCT) for Teaching Orofacial Bone Anatomy to Undergraduate Dental Students
Authors: Savoldi Fabio , Yeung Andy W. K. , Tanaka Ray , Mohammad Zadeh Lisa S. , Montalvao Carla , Bornstein Michael M. , Tsoi James K. H. 
Published: March 2020

Learning bone anatomy of the skull is a complex topic involving three‐dimensional information. The impact of the use of human dry skulls and cone beam computed tomography (CBCT) imaging was investigated in the teaching of undergraduate dental students. Sixty‐four first‐year students in the University of Hong Kong were randomly divided into eight groups. Four teaching methods were tested: (1) CBCT followed by standard lecture, (2) CBCT followed by lecture with skulls, (3) standard lecture followed by CBCT, and (4) lecture with skulls followed by CBCT. After each, students were given a multiple‐choice questionnaire to assess their objective learning outcome (20 questions) and a questionnaire for their subjective satisfaction (10 statements). Surveys were assessed with Cronbach's alpha, Kendall's tau‐b, and principal components analysis. Data were analyzed with Student'st‐test and a one‐way ANOVA (significance α = 0.05). Standard lecture followed by CBCT showed the highest learning outcome score (81.6% ± 14.1%), but no significant difference was present among four teaching methods. Cone beam computed tomography followed by lecture with skulls scored the highest overall subjective satisfaction (4.9 ± 0.8 out of 6), but no significant difference was present among teaching methods. Nevertheless, students' perception of learning was positively influenced by the use of skulls (P = 0.018). The timing of administration of the CBCT did not affect students' subjective satisfaction or objective learning outcome. Students perceived to learn more by using skulls, but their objective learning outcomes were not significantly affected. A discrepancy seems to exist between students' perception of learning and their effective performance.
Effects of virtual reality therapy on perceived pain intensity, anxiety, catastrophising and self‐efficacy among adolescents with cancer
Authors: Sharifpour Shayesteh , Manshaee Gholam Reza , Sajjadian Ilnaz 
Published: March 2020

AbstractBackgroundCancer patients suffer from severe pain due to the nature of their disease, the stages of chemotherapy they go through and its side effects, which may ultimately lead to physical impairments and inability to perform daily activities.ObjectivesThe present study aimed to investigate the effect of virtual reality therapy (VRT) on pain variables among 30 adolescents with cancer at the chemotherapy stage.MethodThis study employed a quasi‐experimental pretest–post‐test design with follow‐up. Thirty adolescents with cancer were selected using a convenience sampling method and were randomly assigned to experimental and control groups. The experimental group underwent eight 30‐min sessions of VRT once a week for 2 months, while the control group were put on a waiting list.ResultsFindings revealed that there were significant differences in pain variables between the control and experimental groups (p < .001). Moreover, the effect of the treatment remained constant during the first and second follow‐up periods.ConclusionsRegarding the prevalence of pain indicators and the effect of these variables on the treatment and improvement of the adolescents with cancer during the chemotherapy stage, the use of this technology is recommended.
Chemodiversity of Essential Oils from Nine Species of Celastraceae
Authors: Camargo Karen C. , Duarte Lucienir P. , Vidal Diogo M. , Pereira Hebert V. , Pereira Rafael C. G. , de Aguilar Mariana G. , de Sousa Grasiely F. , Filho Sidney A. Vieira , Mercadante‐Simões Maria O. , Messias Maria Cristina T. B. , de Oliveira Djalma M. 
Published: March 2020

AbstractExtracts and compounds obtained from several species of Celastraceae family are reported as potential sources of drugs due to their diverse pharmacological properties. Nevertheless, essential oil composition from these species is still little known. This work aimed at the analysis of essential oils obtained from different Brazilian Celastraceae species. A total of seventeen oils were obtained using hydrodistillation process and analyzed by gas chromatography/mass spectrometry (GC/MS). Principal component analysis (PCA) allowed the identification of a chemical composition pattern among the analyzed essential oils. Some compounds were more frequent among Celastraceae species, such as cis‐ and trans‐linalool oxide (14/17 oil samples), nerylacetone (13/17), linalool (11/17), β‐ionone (10/17), α‐ionone (9/17), nerolidol (10/17), decanal (10/17), and dodecanoic acid (10/17). These results contribute to the chemophenetics of Celastraceae species.
Simple “Signal‐Off” Electrochemical Aptasensor Based on Aptamer‐Cu3(PO4)2 Hybrid Nanoflowers/Graphene Oxide for Carcinoembryonic Antigen Detection
Authors: Xu Lingling , Zou Lina , Guo Jiaxin , Cao Ying , Feng Changrui , Ye Baoxian 
Published: March 2020

AbstractA signal‐off aptasensor was described based on well‐designed aptamer‐Cu3(PO4)2 hybrid nanoflowers&graphene oxide composites (aptamer‐Cu3(PO4)2HNF&GO) as an effective sensing platform and molybdophosphate precipitation as the signaling element. The aptamer, as the biorecognition unit grafted on aptamer‐Cu3(PO4)2HNF&GO by the specificity of streptavidin and biotin, captured the carcinoembryonic antigen (CEA) through specific interaction. The molybdophosphate precipitation were formed by the reaction of the aptamer‐Cu3(PO4)2HNF&GO with molybdate (MoO42−). However, the CEA‐aptamer bioconjugate layer films not only hinder electron transfer on the sensing interface, but also impede the formation of molybdophosphate precipitation, resulting that the current signal significantly decreased. So, a simple aptasensor for CEA was constructed with high sensitivity and signal‐off model. Under optimal experimental conditions using square wave voltammetry (SWV), the response peak currents decreases linearly with the logarithm of CEA concentrations in the range from 10 fg mL−1 to 500 ng mL−1. Also, the feasibility of its applications has also been demonstrated in the analysis of clinical serum samples.
Microwave effect on kinetics of paper cups pyrolysis
Authors: Benzennou Soumaya , Laviolette Jean Philippe , Chaouki Jamal 
Published: March 2020

AbstractNot only are microwaves notorious in food heating, but they exhibit interesting properties in different domains including chemical engineering. Their ability to concentrate heat transfer inside dielectric materials enhances process efficiency and permits high heating rates. Nonetheless, their effect on reactions is still controversial. While some researchers believe in non‐thermal effects due to the efficient conversion of microwave energy to enhance reactions without heat dissipation, others assert that microwave frequencies are not high enough to excite molecular bonds. In this study, paper cups pyrolysis is achieved in electrical and microwave TGA using two heating modes. The effect of microwaves on the kinetics of paper cups pyrolysis is shown to depend on the heating regime: at a moderate heating rate, microwave pyrolysis started at a lower temperature, while the pyrolysis in the electrical and microwave TGA have similar kinetic parameters at high heating conditions. This difference is linked with reaction mechanisms. At moderate heating conditions, cellulose decomposes first to an intermediate compound then to final products. The intermediate has a short reaction time and interacts with the microwave. Hence, hot spots at the molecular scale are generated in a short amount of time below the detectable limits of existing temperature measurements media. At a high heating rate, the decomposition of cellulose is direct and no effect is observed.
DICER1 screening in 15 paediatric paratesticular sarcomas unveils an unusual DICER1‐associated sarcoma
Authors: Apellaniz‐Ruiz Maria , Cullinan Noelle , Grant Ronald , Marrano Paula , Priest John R , Thorner Paul S , Goudie Catherine , Foulkes William D 
Published: March 2020

AbstractIndividuals with DICER1 syndrome, a genetic disorder caused by pathogenic germline variants in DICER1, are at increased risk of developing a wide array of predominantly childhood onset conditions, including genitourinary sarcomas. However, data on DICER1 involvement in paratesticular sarcomas have not been published. Herein, we analyse a series of 15 paediatric paratesticular sarcomas and describe in detail the case of a male infant with a paratesticular myxoid tumour, considered to be a low‐grade sarcoma, who also manifested a cystic nephroma, a classic DICER1 syndrome phenotype. He harboured a pathogenic germline DICER1 variant and different somatic hot‐spot mutations in each tumour. The paratesticular tumour showed strong and diffuse expression for WT1 and CD10, an unusual immunophenotype in paediatric sarcomas, but typical of tumours of Müllerian origin. The tumour was postulated to arise from the appendix testis, a Müllerian remnant located in the paratestis. Such an origin would be analogous to other DICER1‐associated non‐epithelial gynaecological tumours, thought to arise from Müllerian derivatives. These findings point towards a key role of DICER1 in Müllerian‐derived structures. Supporting this hypothesis is the fact that the other paratesticular sarcomas from the series were either negative or focally positive for WT1 and for CD10, and none had any DICER1 mutations. In summary, we present the first case of a paratesticular sarcoma associated with DICER1 syndrome, emphasising that paratesticular tumours with an unusual histological appearance may suggest an underlying DICER1 mutation, especially in the presence of a personal or family history of DICER1‐associated disease. In this context, DICER1 mutation testing could lead to changes in clinical care including implementation of cancer care surveillance strategies.
Perfectionistic traits and self‐presentation are associated with negative attitudes and concerns about seeking professional psychological help
Authors: Dang Silvain S. , Quesnel Danika A. , Hewitt Paul L. , Flett Gordon L. , Deng Xiaolei 
Published: March 2020

AbstractNumerous factors influence whether an individual is able and willing to seek professional help for psychological difficulties. One of these may be perfectionism, a multidimensional personality construct that has been linked to poor psychological adjustment. The current study investigated whether perfectionism traits and self‐presentational facets were associated with negative help‐seeking attitudes and concerns about psychotherapy. Samples of university (N = 299) and community (N = 77) men and women completed the Multidimensional Perfectionism Scale, Perfectionistic Self‐Presentation Scale, Attitudes Towards Seeking Professional Help Scale, and Thoughts About Psychotherapy Survey. Various components of perfectionism were associated with both negative help‐seeking attitudes and concerns about psychotherapy. The findings suggest that perfectionistic behaviour may be an important dispositional factor that interferes with seeking and obtaining help for psychological difficulties. Theoretical and clinical implications are discussed.
Catalytic Room‐Temperature C−N Coupling of Amides and Isocyanates by Using Mechanochemistry
Authors: Dayaker Gandrath , Tan Davin , Biggins Naomi , Shelam Asha , Do Jean‐Louis , Katsenis Athanassios D. , Friščić Tomislav 
Published: March 2020

AbstractA mechanochemical route is developed for room‐temperature and solvent‐free derivatization of different types of amides into carbamoyl isatins (up to 96 % conversion or yield), benzamides (up to 81 % yield), and imides (up to 92 % yield). In solution, this copper‐catalyzed coupling either does not take place or requires high temperatures at which it may also be competing with alternative thermal reactivity, highlighting the beneficial role of mechanochemistry for this reaction. Such behavior resembles the previously investigated coupling with sulfonamide substrates, suggesting that this type of C−N coupling is an example of a mechanochemically favored reaction, for which mechanochemistry appears to be a favored environment over solution.
Simple 2 D/0 D CoP Integration in a Metal–Organic Framework‐Derived Bifunctional Electrocatalyst for Efficient Overall Water Splitting
Authors: Lv Siming , Chen Jianmin , Chen Xiaodong , Chen Junying , Li Yingwei 
Published: March 2020

AbstractNon‐noble metal‐based bifunctional electrocatalysts are highly desired for water electrolysis. However, constructing a water electrolyzer using a sole catalyst without compromising either its oxygen evolution reaction (OER) or hydrogen evolution reaction (HER) performance is still challenging. In this study, a simple strategy is developed to integrate 2 D and 0 D CoP in the same metal–organic framework precursor‐derived hollow N‐doped carbon nanotube‐assembled polyhedron (HNCNP). The unique hierarchical structure endows the resulting nanocomposite with both the advantages of more exposed active sites for 2 D and large surface‐to‐volume ratio for 0 D materials, whereas the hollow interior could benefit the charge and mass transfer properties. Thus, CoP/HNCNP@2 D CoP exhibits outstanding OER and HER activity and a low cell voltage when employed as both the anode and cathode in a two‐electrode water electrolyzer. The approach of integrating the same metal phosphide phase with diverse dimensions may inspire new ways to design hierarchical nanostructures for advanced energy conversion applications.