bluuebunny/crossref_metadata_2025_split huggingface dataset:
Corresponding Assessment Scenarios in Laboratory and on-Court Tests: Centrality Measurements by Complex Networks Analysis in Young Basketball Players
Authors: Gobatto C. A. , Torres R. S. , Moura F. A. , Cunha S. A. , Giometti C. B. , Araujo G. G. , Sousa F. A. B. , Manchado-Gobatto F. B. 
Published: May 2020

AbstractBesides technical and tactical aspects, basketball matches involve high aerobic and anaerobic capacities, conferring the final performance of a team. Thus, the evaluation of physical and technical responses is an effective way to predict the performance of athletes. Field and laboratory tests have been used in sports. The first involving high ecological validity and low cost, and the second, greater control and accuracy but not easy application, considering the different preparation phases in a season. This study aimed, through complex networks analysis, to verify whether centrality parameters analysed from significant correlations behave similarly in distinct scenarios (laboratory and on-court), emphasizing aerobic and anaerobic physical parameters and technical performances. The results showed that, in a compelling analysis involving basketball athletes, the studied centralities (degree, betweenness, eigenvector and pagerank) revealed similar responses in both scenarios, which is widely attractive considering the greater financial economy and lower time when applying tests in the field.
A new forensic tool to date human blood pools
Authors: Smith F. R. , Nicloux C. , Brutin D. 
Published: May 2020

AbstractCourtrooms are asking for reliable scientific evidence in order to prevent wrongful convictions. Thus, a more rigorous approach to forensic science approved by scientific methods is promoted. The study of human blood dynamics in the context of forensic science is becoming a widespread research topic, although the physics behind wetting and drying of blood is not completely understood. Based on the morphological changes of drying blood pools, the following work presents a patentable method to quantitatively date these blood pools for forensic purposes. As for drying drops of blood, cracking patterns are observed but they are more disordered. Similar disordered crack patterns are observed in the case of gels, their evaporation process is, therefore, presented since this topic has been thoroughly investigated. We aim to find reliable patterns that could give information concerning the evolution of a blood pool over time to lead to practical application of this knowledge. An empirical model is established between final dried blood patterns and the generating mechanism, yielding application in bloodstain pattern analysis for forensic investigations.
A new method for the estimation of minimum adult frog density from a large-scale audial survey
Authors: Čeirāns Andris , Pupina Aija , Pupins Mihails 
Published: May 2020

AbstractAudial surveys of anuran amphibians (frogs, toads and similar) are cost-effective and allow for the coverage of large areas, but they are usually regarded as unsuitable for population size estimations due to imperfect detection. Our study demonstrated a method for obtaining minimum adult population size estimates from vocalising anuran counts by using sex ratios, life history and vocalising behaviour parameters from other studies. We collected data from 2016 to 2018 for seven taxa on 65 plots (each 25 km2) representing the entirety of Latvia. Among taxa, average breeding waterbody audible detection probabilities ranged from 0.56 to 0.88 per plot, minimum adult frog density (MAFD) estimates were from 12.0 to 51.7 individuals per km2, but the estimated fraction of population covered byMAFDvaried from 57 to 86%. The least accurate density estimates were in taxa with brief calling activity and quiet mating calls (Rana temporaria), and in taxa with a calling activity dependent on the numbers of males in a pond (Bufo bufo). Our study suggests that lek-breeders would be more suitable than explosive-breeding taxa for minimum population size estimates from audial data. The use ofMAFDallowed for coarse minimum population size estimates for the entire country from the audial monitoring data, these ranged from 3.7 ± 0.5 thousand (Bombina bombina) to 1.64 ± 0.47 million (B.bufo) adults.
Inflammatory Cytokines During Cardiac Rehabilitation After Heart Surgery and Their Association to Postoperative Atrial Fibrillation
Authors: Racca Vittorio , Torri Anna , Grati Paola , Panzarino Claudia , Marventano Ivana , Saresella Marina , Castiglioni Paolo 
Published: May 2020

AbstractInflammation is associated with atrial fibrillation (AF), but little is known about the association of AF with the inflammatory serum cytokines after the acute postoperative phase. Thus, we aimed to explore how plasma cytokines concentrations modify during a 3-week cardiac rehabilitation after heart surgery, comparing patients who developed postoperative AF (POAF) and those with permanent AF with patients free from AF (NoAF group). We enrolled 100 consecutive patients and 40 healthy volunteers as a control group. At the beginning of cardiac rehabilitation, 11 days after surgery, serum levels of MPO, PTX3, ADAM17, sST2, IL-25, and IL-33 were dramatically higher, whereas TNFα and IL-37 levels were much lower in NoAF, POAF, and permanent AF patients than in the healthy volunteers. After rehabilitation, most of the cytokines changed tending towards normalization. POAF patients (35% of the total) had higher body mass index and abdominal adiposity than NoAF patients, but similar general characteristics and risk factors for POAF. However, ADAM-17 and IL-25 were always lower in POAF than in NoAF patients, suggesting a protective role of IL-25 and ADAM 17 against POAF occurrence. This finding could impact on therapeutic strategies focusing on the postoperative prophylactic antiarrhythmic interventions.
Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis
Authors: Jain Piyush , Materazzi Serena , De Logu Francesco , Rossi Degl’Innocenti Duccio , Fusi Camilla , Li Puma Simone , Marone Ilaria M. , Coppi Elisabetta , Holzer Peter , Geppetti Pierangelo , Nassini Romina 
Published: May 2020

AbstractPain evoked by visceral inflammation is often ‘referred’ to the somatic level. Transient receptor potential ankyrin 1 (TRPA1) has been reported to contribute to visceral pain-like behavior in dextran sulfate sodium (DSS)-evoked colitis. However, the role of TRPA1 in somatic component of hypersensitivity due to visceral inflammation is unknown. The present study investigated the role of TRPA1 in colitis-evoked mechanical hypersensitivity at the somatic level. Colitis was induced in mice by adding DSS to drinking water for one week. Control and DSS-treated mice were tested for various parameters of colitis as well as mechanical pain sensitivity in abdominal and facial regions. DSS treatment caused mechanical hypersensitivity in the abdominal and facial skin. Pharmacological blockade or genetic deletion of TRPA1 prevented the colitis-associated mechanical hypersensitivity in the abdominal and facial skin areas although the severity of colitis remained unaltered. DSS treatment increased expression of TRPA1 mRNA in cultured dorsal root ganglion (DRG) neurons, but not trigeminal ganglion neurons, and selectively enhanced currents evoked by the TRPA1 agonist, allyl isothiocyanate, in cultured DRG neurons. Our findings indicate that the TRPA1 channel contributes to colitis-associated mechanical hypersensitivity in somatic tissues, an effect associated with upregulation of TRPA1 expression and responsiveness in DRG nociceptors.
Bright and fast scintillations of an inorganic halide perovskite CsPbBr3 crystal at cryogenic temperatures
Authors: Mykhaylyk V. B. , Kraus H. , Kapustianyk V. , Kim H. J. , Mercere P. , Rudko M. , Da Silva P. , Antonyak O. , Dendebera M. 
Published: May 2020

AbstractHighly efficient scintillation crystals with short decay times are indispensable for improving the performance of numerous detection and imaging instruments that use- X-rays, gamma-quanta, ionising particles or neutrons. Halide perovskites emerged recently as very promising materials for detection of ionising radiation that motivated further exploration of the materials. In this work, we report on excellent scintillation properties of CsPbBr3 crystals when cooled to cryogenic temperatures. The temperature dependence of luminescence spectra, decay kinetics and light yield under excitation with X-rays and α-particles was investigated. It is shown that the observed changes of spectral and kinetic characteristics of the crystal with temperature can be consistently explained by radiative decay of free excitons, bound and trapped excitons as well as electron-hole pairs originating from their disintegration. It has been found that the crystal exhibits a fast decay time constant of 1 ns at 7 K. The scintillation light yield of CsPbBr3 at 7 K is assessed to be 50,000 ± 10,000 ph/MeV at excitation with 12 keV X-rays and 109,000 ± 22,000 ph/MeV at excitation with α-particles of 241Am. This finding places CsPbBr3 in an excellent position for the development of a new generation of cryogenic, efficient scintillation detectors with nanosecond response time, marking a step-change in opportunities for scintillator-based applications.
Insight into the antiviral activity of synthesized schizonepetin derivatives: A theoretical investigation
Authors: Baghban Alireza , Mosavi Amir 
Published: May 2020

AbstractThe antiviral activity of schizonepetin derivatives 1A-1C were investigated via theoretical methods and results are compared with experimental results. The derivatives 1 A and 1 C have the highest and the lowest antiviral activity, respectively. The interactions of derivatives 1A-1C and BN-nanotube are examined. Results show that, derivatives 1A-1C can effectively interact with BN-nanotube (9, 9) and their adsorptions are favorable. The energy of derivative 1 A is higher than derivatives 1B and 1 C. The derivative 1 A has highest absolute µ, ω and ∆N values and it has lowest absolute ƞ value. Results show that, theoretical and experimental trends of antiviral activity of derivatives 1A-1C were similar, successfully.
Diffuse γ-ray emission toward the massive star-forming region, W40
Authors: Sun Xiao-Na , Yang Rui-Zhi , Liang Yun-Feng , Peng Fang-Kun , Zhang Hai-Ming , Wang Xiang-Yu , Aharonian Felix 
Published: May 2020

We report the detection of high-energy γ-ray signal towards the young star-forming region, W40. Using 10-yr Pass 8 data from the Fermi Large Area Telescope (Fermi-LAT), we extracted an extended γ-ray excess region with a significance of ~18σ. The radiation has a spectrum with a photon index of 2.49 ± 0.01. The spatial correlation with the ionized gas content favors the hadronic origin of the γ-ray emission. The total cosmic-ray (CR) proton energy in the γ-ray production region is estimated to be the order of 1047 erg. However, this could be a small fraction of the total energy released in cosmic rays (CRs) by local accelerators, presumably by massive stars, over the lifetime of the system. If so, W40, together with earlier detections of γ-rays from Cygnus cocoon, Westerlund 1, Westerlund 2, NGC 3603, and 30 Dor C, supports the hypothesis that young star clusters are effective CR factories. The unique aspect of this result is that the γ-ray emission is detected, for the first time, from a stellar cluster itself, rather than from the surrounding “cocoons”.
Relative thermodynamic stability of the [C,N,O] linkages as an indication of the most abundant structures in the ISM
Authors: Fourré I. , Matz O. , Ellinger Y. , Guillemin J.-C. 
Published: May 2020

Context. Most of the compounds detected in the interstellar medium (ISM) that possess isomers correspond to the thermodynamically most stable isomer of a given chemical formula. Using the minimun energy principle (MEP) as a pragmatic tool is particularly efficient for less than six atoms, but for larger systems combinatorial analysis gives an intractable numbers of isomers.
Aims. To make the MEP more applicable, we look for a chemical sieve to filter the thermodynamic data needed to determine which isomers of complex organic molecules (COMs) have higher chances of being present in the ISM. To do so, we investigate whether the nature of the [C,N,O] elementary fragment can be determinant for the stabilization of COMs, taking C2H3NO as a case study.
Methods. We employed standard quantum chemistry methods to determine the ordering of fragments and derivatives on the energy scale. Density functional theory treatments were systematically performed, together with high-level coupled cluster calculations to refine relative energies.
Results. For C2H3NO we find methylisocyanate CH3NCO, which is a compound that was very recently detected in the ISM, to be the most stable isomer in a corpus of 40 isomers of lowest energy. In neutral form we find the stability ordering of NCO > ONC; the same is true for the negative ion. Attachments of R=H, CH3, C2H5, HC2, H2CCH, and C6H5 and metals Al and Mg to the nitrogen atom of the NCO fragment provide the most stable isomers. The energy differences between the successive isomers on the energy scale R-NCO, R-OCN, R-CNO, and R-ONC are of the same order of magnitude for all carbonaceous R.
Conclusions. Combining the criterion of most stable linkage with the MEP concept should greatly reduce the window of potential targets to be searched for in the ISM. Compounds containing the NCO linkage should be preferential targets of future research.
Evaluation of endoscopic ultrasound fine-needle aspiration versus fine-needle biopsy and impact of rapid on-site evaluation for pancreatic masses
Authors: de Moura Diogo T.H. , McCarty Thomas R. , Jirapinyo Pichamol , Ribeiro Igor B. , Hathorn Kelly E. , Madruga-Neto Antonio Coutinho , Lee Linda S. , Thompson Christopher C. 
Published: May 2020

Abstract
Background and study aims Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) is traditionally considered a first-line strategy for diagnosing pancreatic lesions; however, given less than ideal accuracy rates, fine-needle biopsy (FNB) has been recently developed to yield histological tissue. The aim of this study was to compare diagnostic yield and safety between EUS-FNA and EUS-FNB in sampling of pancreatic masses.
Patients and methods This was a multicenter retrospective study to evaluate efficacy and safety of EUS-FNA and EUS-FNB for pancreatic lesions. Baseline characteristics including sensitivity, specificity, and accuracy, were evaluated. Rapid on-site evaluation (ROSE) diagnostic adequacy, cell-block accuracy, and adverse events were analyzed. Subgroup analyses comparing FNA versus FNB route of tissue acquisition and comparison between methods with or without ROSE were performed. Multivariable logistic regression was also performed.
Results A total of 574 patients (n = 194 FNA, n = 380 FNB) were included. Overall sensitivity, specificity, and accuracy of FNB versus FNA were similar [(89.09 % versus 85.62 %; P = 0.229), (98.04 % versus 96.88 %; P = 0.387), and 90.29 % versus 87.50 %; P = 0.307)]. Number of passes for ROSE adequacy and cell-block accuracy were comparable for FNA versus FNB [(3.06 ± 1.62 versus 3.04 ± 1.88; P = 0.11) and (3.08 ± 1.63 versus 3.35 ± 2.02; P = 0.137)]. FNA + ROSE was superior to FNA alone regarding sensitivity and accuracy [91.96 % versus 70.83 %; P < 0.001) and (91.80 % versus 80.28 %; P = 0.020)]. Sensitivity of FNB + ROSE and FNB alone were superior to FNA alone [(92.17 % versus 70.83 %; P < 0.001) and (87.44 % versus 70.83 %; P < 0.001)]. There was no difference in sensitivity though improved accuracy between FNA + ROSE versus FNB alone [(91.96 % versus 87.44 %; P = 0.193) and (91.80 % versus 80.72 %; P = 0.006)]. FNB + ROSE was more accurate than FNA + ROSE (93.13 % versus 91.80 %; P = 0.001). Multivariate analysis showed ROSE was a significant predictor of accuracy [OR 2.60 (95 % CI, 1.41–4.79)]. One adverse event occurred after FNB resulting in patient death.
Conclusion EUS-FNB allowed for more consistent cell-block evaluation as compared to EUS-FNA. EUS-FNA + ROSE was found to have a similar sensitivity to EUS-FNB alone suggesting a reduced need for ROSE as part of the standard algorithm of pancreatic sampling. While FNB alone produced similar diagnostic findings to EUS-FNA + ROSE, FNB + ROSE still was noted to increase diagnostic yield. This finding may favor a unique role for FNB + ROSE, suggesting it may be useful in cases when previous EUS-guided sampling may have been indeterminate.
Multimodal intervention for avoiding inappropriate cessation of aspirin prior to outpatient endoscopy
Authors: Ellison Parker L. , Holman Nathan , Wallace Kristin , Cote Gregory A. , Elmunzer B. Joseph , Brock Andrew S. 
Published: May 2020

Abstract
Background and study aims Existing guidelines recommend continuation of aspirin therapy prior to outpatient endoscopic procedures, as it reduces peri-procedural cardiovascular events and is not associated with an increased risk of bleeding. Despite this, many patients at our institution inappropriately alter their aspirin prior to endoscopy. We sought to identify why this occurs and implement an intervention that could reduce improper aspirin alteration.
Patients and methods All adult patients undergoing outpatient endoscopy at the Medical University of South Carolina were administered a survey querying demographics, aspirin use, endoscopic procedure, thromboembolic risk factors, and pre-procedural aspirin alteration, if any. An intervention involving revised written and verbal instructions as well as an automated voicemail aimed at ensuring patients adhere to guidelines was then undertaken. The same survey was administered after the intervention to assess for improved adherence.
Results A total of 240 patients from the initial survey reported daily aspirin use, of which 114 (47.5 %) inappropriately altered aspirin therapy. A total of 182 patients from the post-intervention survey reported daily aspirin use, of which 66 (36.3 %) inappropriately altered aspirin therapy. This was a statistically significant reduction (P = 0.04), which included adjustments for age, sex, procedure type, and thromboembolic risk.
Conclusions A high proportion of patients at our institution inappropriately alter aspirin therapy prior to outpatient endoscopy. The reasons for this behavior include patient self-direction, misguidance from staff, and instruction from other physicians. This alteration can be reduced significantly through an intervention that educates both patients and staff on continuation of aspirin therapy prior to outpatient endoscopy.
Technical feasibility and safety of transluminal antegrade dilation for hepaticojejunostomy stricture using a novel fine-gauge electrocautery dilator (with video)
Authors: Ogura Takeshi , Nishioka Nobu , Yamada Masanori , Yamada Tadahiro , Ueno Saori , Matsuno Jyun , Ueshima Kazuya , Yamamoto Yoshitaro , Okuda Atsushi , Ashida Reiko , Higuchi Kazuhide 
Published: May 2020

Abstract
Background and study aims A novel fine-gauge electrocautery dilator (ED) has recently become available in Japan. The current study evaluated the safety and feasibility of transluminal antegrade dilation for hepaticojejunal stricture (HJS) using this novel ED.
Patients and methods Patients who with complicated HJS were retrospectively enrolled. The primary and secondary endpoints of this study were rates of technical success defined as functional antegrade HJS dilation using the novel ED and types of adverse events, respectively. A total of 22 patients were enrolled. Among them, six were treated using an enteroscopic approach due to the absence of bile duct dilation or patient refusal to undergo EUS-HGS. Therefore, 16 patients underwent EUS-HGS.
Results The procedure was successful in 15 of 16 patients (93.8 %). The contrast medium flowed from the intrahepatic bile duct to the intestine of 14 of 15 patients (93.3 %). The resolution rate of HJS was 13 of 14 (92.9 %) at 6 months.
Conclusion Our technique might offer a new option with which to treat HJS, although a prospective study with long-term follow-up is needed.
Nodularity-like appearance in the cardia: novel endoscopic findings for Helicobacter pylori infection
Authors: Toyoshima Osamu , Nishizawa Toshihiro , Sakitani Kosuke , Yamakawa Tadahiro , Watanabe Hidenobu , Yoshida Shuntaro , Nakai Yousuke , Hata Keisuke , Ebinuma Hirotoshi , Suzuki Hidekazu , Koike Kazuhiko 
Published: May 2020

Abstract
Background and study aims Helicobacter pylori-associated nodular gastritis, which is associated with follicular lymphoid hyperplasia, is mainly recognized in the antrum. However, we have also observed nodularity-like appearance in the cardia. This study aimed to investigate the clinical signiﬁcance of cardiac nodularity-like appearance in H. pylori-associated gastritis.
Patients and methods Patients who underwent esophagogastroduodenoscopy and were evaluated for H. pylori infection for the ﬁrst time were enrolled. A nodularity-like appearance in the cardia was defined as a miliary nodular appearance or scattered appearances of small circular whitish coloration. H. pylori infection was diagnosed according to serum anti-H. pylori antibody and the urea breath test or histology. Accuracy of the H. pylori infection diagnoses based on nodularity-like appearance were assessed.
Results Among 265 patients, 42 patients (15.8 %) were diagnosed as positive for H. pylori. Cardiac nodularity-like appearance and antral nodularity were recognized in 25 and 15 patients, respectively. In accuracy of predicting H. pylori by cardiac nodularity-like appearance, specificity was 0.996, sensitivity was 0.571, positive predictive value was 0.960, negative predictive value was 0.925, and accuracy was 0.928. The sensitivity of cardiac nodularity-like appearance was significantly higher than that of antral nodularity (P = 0.0284).
Conclusions Cardiac nodularity-like appearance had a high accuracy rate for H. pylori infection diagnosis. Cardiac nodularity-like appearance was found more frequently than antral nodularity.