bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cameraless sensor fusion: developing a cost-effective driver assistance system using radar and ultrasonic sensor
Authors: S. Sasikumar , B. Aravind Balaji , A. Joshuva , Deivanayagampillai Nagarajan 
Published: December 2024

Purpose
This paper aims to develop a cost-effective, camera-less advanced driver assistance system (ADAS) for electric vehicles. It will use sensor fusion of ultrasonic and radar sensors to implement adaptive cruise control (ACC), blind spot detection (BSD) and reverse parking (RP).

Design/methodology/approach
The system was tested on an electric vehicle test bench, using strategically placed ultrasonic and radar sensors. Sensor fusion enabled accurate object detection and distance measurement. The system’s performance was evaluated through simulated obstacle scenarios, with responses monitored via a graphical user interface. Sensor and GPS data were transmitted to the cloud for potential vehicle-to-vehicle communication.

Findings
The sensor fusion approach effectively supported ACC, BSD and RP functions, demonstrating accuracy in obstacle detection, speed adjustment and emergency braking. The real-time system visualization confirmed reliability across various scenarios and cloud integration showed promise for future communication enhancements.

Research limitations/implications
Ultrasonic and radar sensors have limited range and accuracy compared to cameras. Ultrasonic sensors are less effective at longer distances and in adverse weather conditions, whereas radar can face challenges in detecting small or stationary objects. Sensor performance can be affected by environmental factors such as rain, fog or snow, which may reduce the effectiveness of both ultrasonic and radar sensors. Sensor performance can be affected by environmental factors such as rain, fog or snow, which may reduce the effectiveness of both ultrasonic and radar sensors.

Practical implications
Improved obstacle detection and collision avoidance contribute to overall vehicle safety. Drivers benefit from advanced features like ACC, BSD and RP without the high cost of traditional camera-based systems. The use of ultrasonic and radar sensors makes advanced driver assistance features more affordable, allowing broader adoption across various vehicle segments, including budget-friendly and mid-range models. The system’s responsiveness and obstacle detection capabilities can lead to more efficient driving, reducing the likelihood of accidents and improving traffic flow.

Social implications
Enhanced safety features such as ACC, BSD and RP contribute to reducing traffic accidents and injuries. By making advanced driver assistance features more affordable, the system improves vehicle safety for a broader range of drivers, including those in lower-income brackets. The introduction of such systems can raise public awareness about the benefits of ADAS technologies and their role in enhancing road safety.

Originality/value
This study introduces a novel ADAS system that eliminates the need for cameras by leveraging the strengths of radar and ultrasonic sensors. The approach offers a practical and innovative solution for enhancing vehicle safety at a reduced cost.
User generated content versus mainstream media influence on hot spring tourism destination image formation
Authors: Zain Nur Adilah Md , Hanafiah Mohd Hafiz , Asyraff Muhammad Aliff , Ismail Hazmal , Bafadhal Aniesa Samira 
Published: December 2024

Purpose
This study aims to compare the influence of user-generated content and mainstream media on the formation of hot springs tourists’ cognitive and affective destination image and, secondly, how these image formations impact travellers’ satisfaction and loyalty.

Design/methodology/approach
Data were collected from 575 international tourists who visited hot spring destinations. The non-probability purposive sampling approach was used, and the partial least squares structural equation modelling (PLS-SEM) assessment was used to test the proposed hypotheses.

Findings
This study found no significant differences in the roles of user-generated content and mainstream media in shaping tourists’ perceptions. User-generated content and mainstream media significantly influence cognitive and affective image formation. Tourists’ cognitive image significantly influences their satisfaction with hot springs visitation; however, affective image is an insignificant predictor of satisfaction. Ultimately, tourist satisfaction is crucial to tourists’ loyalty to hot springs destinations.

Originality/value
Leveraging uses and gratifications theory, this study introduces a novel framework that integrates user-generated content and mainstream media to dissect their combined impact on destination image formation. It highlights the theoretical understanding of media consumption and provides groundbreaking insights into optimising tourism strategies and fostering enduring destination loyalty.
Potential postmortem microbial biomarkers of infant and younger children death investigation
Authors: Mikles Bethany , Schmidt Carl J. , Benbow M. Eric , Jordan Heather R. , Pechal Jennifer L. 
Published: December 2024

AbstractMicrobial communities associated with the human body are highly dynamic and reflect the host environment and lifestyle over time. Studies show death is no exception, with data demonstrating similar antemortem and postmortem microbiomes up to 48 h following death. These predictable microbial biomarkers can inform death investigation by helping to estimate the postmortem interval and build models to identify cause and manner of death. However, no attempts have been made to model potential microbial biomarkers in pediatric (≤2 years) deaths. This study provided a cross‐sectional survey of the microbiota of 53 pediatric cases (black, white, both sexes) seen in Wayne County, Michigan. Autopsy cases represented accidents, homicides, or natural causes. Postmortem microbiome were collected by swabbing the eyes, ears, nose, mouth, umbilicus, brain, rectum, trabecular space, and cardiac blood. 16S rRNA sequence analyses indicated that sex, race, age, body site, and manner of death (MOD) had significant effects on microbiome composition, with significant interactions among MOD, race, and age. Amplicon sequence variants identified intra‐ and interhost dispersion of the postmortem microbiome depending on death circumstance. Among manners of death, non‐accidental deaths were significantly distinct from all other deaths, and among body sites the rectum was distinct in its microbial composition. There is a real need for robust postmortem microbiome before it can be standardized as a practical tool for use in forensic investigation or public health. These results inform postmortem microbial variability during pediatric death investigation that contributes to a larger effort to understand the postmortem microbiome.
The crucial role played by material trace analysis in resolving a murder vs. suicide dilemma
Authors: Baciu Dora Domnica , Tașbac Bogdan Alexandru , Trușcă Roxana , Mihăiescu Dan Eduard 
Published: December 2024

AbstractIn the case of a young woman's death by falling from the window of her boyfriend's sixth‐floor apartment, investigators needed to determine whether the fall was suicidal or if the victim was forcibly pushed. The incident occurred at night, with her boyfriend being the only witness to how the fall happened. Establishing the origin of the material traces found on the woman's stockings and shoes, along with other clues, played a crucial role in resolving this dilemma. The traces found on the stockings and samples collected from the building's external wall were analyzed using digital stereomicroscopy, High‐resolution scanning electron microscopy (HRSEM) coupled with energy dispersive X‐ray spectroscopy (EDX), and optical microscopy. Chlorophyll presence on both the victim's stockings and the surface of the building façade was confirmed using Raman spectroscopy. The inorganic traces found on the shoes and the external wall were examined using stereomicroscopy and HRSEM coupled with EDX and were found to be similar in texture and elemental composition. The correspondence between the biological structures and mineral fragments, along with the dynamic friction marks found on the woman's body and shoes, confirmed physical contact between the victim and the external wall. These findings led to the conclusion that the victim struggled for her life and the fall resulted from a criminal act.
Molecular characterization of Bombyx mori C‐type lectin 21 in innate immune responses
Authors: Park Min Ji , Kim Bo Yeon , Yoon Hyung Joo , Kim Kee Young , Kim Seong Wan , Kim Sun Young , Lee Kwang Sik , Jin Byung Rae 
Published: December 2024

AbstractInsect C‐type lectins (CTLs) play a vital role in recognizing and binding pathogen‐associated molecules, such as carbohydrate moieties, to initiate immune responses. Although the characteristics of Bombyx mori C‐type lectin 21 (BmCTL21), named BmLBP, have been reported, its molecular mechanisms, including expression patterns during immune responses and recognition and binding behaviors, remain poorly understood. Therefore, this study aims to explore the molecular characterization of BmCTL21 in innate immune responses. The findings reveal that BmCTL21 is upregulated in the fat body and subsequently transported to hemocytes, where it binds to the surface of Gram‐negative bacteria during microbial infection. Additionally, BmCTL21 RNAi treatment leads to a decline in BmCTL21 expression, which results in the suppression of phenoloxidase activity. Moreover, recombinant BmCTL21 was found to recognize carbohydrates, such as lipopolysaccharide, mannan and N‐acetyl‐
d‐glucosamine, in a Ca2+‐independent manner, and binds to the cell walls of Gram‐negative bacteria, Gram‐positive bacteria and fungi. In summary, this study offers new insights into the molecular mechanisms and functional behaviors of BmCTL21 in the innate immune response of silkworms.
Assessment of transglutaminase catalyzed cross‐linking on the potential allergenicity and conformation of heterologous protein polymers
Authors: Xing Guangliang , Liu Jia , Wang Ruohan , Wu Yitong 
Published: December 2024

AbstractTransglutaminase (TGase)‐mediated cross‐linking has gained significant attention due to its potential to reduce the allergenicity of food proteins. This study investigates the effects of TGase cross‐linking on allergenicity and conformational modifications in a dual‐protein system comprising soy protein isolate (SPI) and β‐lactoglobulin (β‐LG). The results showed that TGase cross‐linking effectively decreased the allergenic potential of both SPI and β‐LG, with a more pronounced reduction observed in the allergenicity of soy protein in the dual‐protein system. SDS‐PAGE analysis revealed that the 7S and 11S subunits of soy protein were more easily cross‐linked than β‐LG. Secondary structure analysis indicated that TGase treatment disrupted β‐sheet structures, increased the content of random coils, and enhanced protein flexibility. Ultraviolet absorption and intrinsic fluorescence analyses confirmed these structural alterations, with TGase treatment exposing additional aromatic amino acids. A reduction in free sulfhydryl groups and altered intermolecular forces further corroborated the occurrence of cross‐linking. These findings suggest that TGase‐mediated cross‐linking effectively reduced the allergenicity of SPI and β‐LG by modifying their conformations, offering potential strategies for the development of hypoallergenic dual‐protein food products.Practical ApplicationThis study has practical applications in the food industry to develop hypoallergenic food products, particularly those that combine soy and dairy proteins. By using TGase to cross‐link these proteins, the allergenicity can be reduced, resulting in products that are safer for consumers with food allergies.
Heterologous Gene Expression in Chlamydomonas reinhardtii Chloroplast by Heterologous Promoters and Terminators, Intercistronic Expression Elements and Minichromosome
Authors: Guo Yunling , Xiong Hui , Fan Qiuling , Duanmu Deqiang 
Published: December 2024

ABSTRACTChlamydomonas reinhardtii, a model green alga for expressing foreign proteins, faces challenges in multigene expression and enhancing protein expression level in the chloroplast. To address these challenges, we compared heterologous promoters, terminators and intercistronic expression elements (IEEs). We transformed Chlamydomonas chloroplast with a biolistic approach to introduce vectors containing the NanoLuc expression unit regulated by Chlamydomonas or tobacco promoters and terminators. We observed that tobacco promoters PrbcL and PpsbA could not effectively regulate protein expression, whereas tobacco terminators TrbcL and Trps16 did not affect the expression of Nluc protein. Further exploration of IEEs specific to Chlamydomonas revealed that Cr‐IEE2 had a minor effect on both upstream and downstream protein expression, whereas Cr‐IEE5 significantly influenced downstream protein expression. In contrast, tobacco IEE was found to be unsuitable for driving protein expression in Chlamydomonas. Additionally, VOR element and Rep protein derived from beet curly top geminivirus were able to form a minichromosome in Chlamydomonas chloroplast, and this system could enhance protein expression level compared to the traditional method of site‐specific integration in the plastome. This study highlights the potential of IEEs and minichromosome in facilitating heterologous protein expression in Chlamydomonas chloroplast.
Identifying Risk Factors Associated With False‐Negative Results in US‐Guided Percutaneous Transthoracic Needle Lung Biopsy of Subpleural Pulmonary Lesions
Authors: Yi Jiawei , Shen Mengjun , He Junhui , Xia Runhe , Zhao Xinyu , Wang Yin 
Published: December 2024

ABSTRACTBackgroundThis study aims to investigate the factors influencing false‐negative results in ultrasound‐guided percutaneous transthoracic needle lung biopsy results (US‐PTLB).Materials and MethodsThis ambispective cohort study included patients with subpleural pulmonary lesions who underwent US‐PTLB with benign pathological findings between April 2017 and June 2022 (retrospective cohort) and between July 2022 and October 2022 (prospective cohort). In the retrospective cohort, comparative and logistic regression analyses were performed to identify independent risk factors for false‐negative biopsy results. Stratified analyses based on these risk factors were performed in the prospective cohort.ResultsThe retrospective cohort included 1747 (true‐negative: false‐negative, 1321:426) patients with negative biopsy results, which were analyzed by comparative and logistic regression analyses, and the results demonstrated that advanced age (> 56 years) (OR = 1.08, 95% CI: 1.07–1.09), small‐sized lesions (< 3 cm) (OR = 1.80, 95% CI: 1.38–2.34), lesions with necrosis (OR = 3.00, 95% CI: 2.29–3.92), contrast‐enhanced ultrasound (CEUS) showing hyper‐enhancement (OR = 5.87, 95% CI: 4.09–8.42) or iso‐enhancement (OR = 2.81, 95% CI: 2.05–3.83), and the presence of hemoptysis (OR = 11.82, 95% CI: 5.16–27.08) or pneumothorax (OR = 7.90, 95% CI: 2.89–21.58) during the puncture were independent predictors of false‐negative US‐PTLB results. The results of stratified analyses in the prospective cohort were consistent with the retrospective cohort.ConclusionRisk factors associated with false‐negative results included advanced age (> 56 years), small‐sized lesion (< 3 cm), presence of necrosis in the lesion, CEUS showing hyper‐enhancement or iso‐enhancement of the lesion, and hemoptysis or pneumothorax during puncture.Trial Registration: Number: ChiCTR2000029749
Pathological Complete Response to a Single Dose of Pembrolizumab‐Based Chemoimmunotherapy for Squamous Cell Carcinoma of the Lung: A Case Report
Authors: Matsumura Yugo , Ichihara Seiya , Nii Kaori , Nanjo Kazumasa , Kadota Naoki , Okano Yoshio , Machida Hisanori , Hatakeyama Nobuo , Hino Hiroyuki , Naruse Keishi , Shinohara Tsutomu , Sakiyama Shoji , Takeuchi Eiji 
Published: December 2024

ABSTRACTWe herein describe a patient with non‐small‐cell lung cancer who achieved pCR with a single dose of pembrolizumab‐based chemoimmunotherapy followed by surgery. A 61‐year‐old man was referred to our hospital with wheezing and an abnormal chest shadow. Squamous cell carcinoma of the left lower lobe, cT2aN1M0 stage IIB, was diagnosed and pembrolizumab‐based chemoimmunotherapy was initiated at the patient's request. One month later, chest CT revealed new ground‐glass opacities of the lungs, which were judged to be a CTCAE grade 2 pneumonitis due to an immune‐related adverse event (irAE). Therefore, steroid therapy was initiated. Prednisolone was tapered and discontinued as symptoms improved. A sleeve resection of the left lower lobe was performed, and a pathological complete response (pCR) was confirmed in a resected specimen. There has been no recurrence for 1 year and 7 months without treatment. This is the first case report of pCR to a single dose of chemoimmunotherapy followed by surgery for lung cancer. The present results suggest the potential of a single dose of chemoimmunotherapy to achieve pCR and cause irAEs in some patients.
Preliminary Survey of Native and Invasive Carnivores in a Community Forest in Southwestern Madagascar
Authors: Axel Anne C. , Whetzel Megan , Harshbarger Brynn M. , Randria Ekena 
Published: December 2024

ABSTRACTThe fosa (Cryptoprocta ferox) is an endemic carnivore typically found in large protected areas of Madagascar. Here, we report the presence of juvenile fosa in Milomboka Community Forest in southwestern Madagascar, a region where very few occurrences of the species have been reported. We obtained camera trap videos of fosa and two exotic carnivores, the forest cat (Felis catus) and small Indian civet (Viverricula indica), during a 48‐trap night camera trapping study. These findings highlight the value of small community conservation areas for biodiversity, even when they serve as production landscapes.
Co‐creating an Indigenous‐led virtual health services model for Indigenous Australians living with chronic disease
Authors: Nasir Bushra Farah , MacAskill William , Leedie Floyd , Martin Priya , Alam Khorshed , Wallis Katharine , McGrail Matthew , Kondalsamy‐Chennakesavan Srinivas 
Published: December 2024

AbstractObjectiveTo describe the co‐design process and understand consumer perspectives of a virtual health services (VHS) model of primary healthcare delivery, for Indigenous Australians with chronic disease and living in regional, rural, and remote Queensland.DesignUsing decolonising methodologies, the study used an Indigenous consensus method to undertake the co‐design process and generate findings. For analysis, a qualitative interpretive‐description framework was applied. Thematic analysis generated themes, describing consumer perspectives of virtual healthcare models.SettingThe Goondir Health Services (Aboriginal Community Controlled Health Organisation) operating clinics in rural and remote Queensland.ParticipantsFourteen Indigenous VHS consumers who resided in Modified Monash Model 3–7 communities across Queensland, met the eligibility criteria and provided informed consent.ResultsTwo themes emerged: (1) personalised approaches to autonomous care using digital technologies, with two sub‐themes of the benefits and challenges of technology, and the integration of culturally inclusive healthcare elements; (2) person‐centred, culturally appropriate healthcare elements within a VHS model, with three sub‐themes on the vital role of health coaches, the importance of community connections, and enabling holistic personalised healthcare access.ConclusionThis study provides important consumer perspectives on the potential of VHS models of health care to empower Indigenous healthcare service consumers. VHS holds promise on multiple fronts: improved access, timeliness, continuity of care, and culturally sensitive health care, enabling improved self‐management of chronic conditions, and provide crucial support from local Indigenous healthcare providers within the community. Future research on the sustainability and impact of personalised, consumer‐centric digital health services in Indigenous populations is essential.
Rural and metropolitan applicants' experiences of the admissions process for a provisional entry regional medical training pathway
Authors: Fox Jordan , Saluja Sonia , Batacan Romeo , Pullen Candice , Yong Faith , McGrail Matthew 
Published: December 2024

AbstractObjectiveTo explore the experiences and perceptions of rural and metropolitan applicants preparing for and completing all admission components for a provisional entry regional medical pathway.SettingProvisional entry regional medical pathway.ParticipantsProvisional entry (school‐leaver) applicants (N = 18) who completed a Multiple Mini‐Interview (MMI).DesignApplicants were invited to participate in a semi‐structured interview regarding their experiences of the admissions process relative to their background (rural/metropolitan origin). A constructivist approach with a social accountability lens was taken for these semi‐structured interviews.ResultsThemes were related to whether the applicants were classified as rural or metropolitan origin and the impact of the applicant's geographical location and connections to the local community, differences in local school and social support, and challenges in allocating medical school preferences.ConclusionOverall, applicant perceptions and experiences of the admissions process were influenced both positively and negatively by whether they were of rural or metropolitan origin. Strategies are required to ensure applicants with genuine rural interest, whether they are of rural or metropolitan origin, have access to sufficient support and resources while applying to regional medical pathways to ensure they are not disadvantaged, thus meeting admissions goals of the program.
Perceiving immunity, predicting somatic symptoms: Validation of the ‘Perceived Immunity’ scale and its association with daily health
Authors: Mizrachi Nofar , Kube Tobias , Rozenkrantz Liron 
Published: December 2024

AbstractObjectiveWhile ample research links health beliefs to physical health in both healthy and clinical populations, the specific health beliefs that drive this effect remain underexplored. Addressing this gap is critical for mechanistic examinations and targeted intervention development. Building on previous work, this study aimed to assess subjective beliefs about immune system efficacy and develop a novel Perceived Immunity scale.MethodsAcross three studies (total N = 378; Study 1: N = 206 healthy; Study 2: N = 132 healthy and N = 40 with immune‐related diseases; and Study 3: subset of N = 87 from Study 2), we examine Perceived Immunity scale's validity, reliability, and association with everyday physical health.ResultsPerceived immunity demonstrated excellent internal consistency (Cronbach alpha = 0.9), strong construct validity (all items were loaded onto one factor) and structural validity, including convergence validity with scales assessing subjective health perceptions, and discriminant validity from scales measuring external health control. These findings were replicated across different cohorts. Furthermore, regression analyses revealed significant correlations with daily physical health measures, specifically somatic symptoms, across cohorts (all β > −0.347, all p < .001) and sick leave days (all β = −0.174, all p < .045). These associations were stronger in individuals with immune‐related conditions. Finally, Perceived Immunity exhibited good test–retest reliability (interclass correlation coefficient = 0.74) and prospectively predicted somatic symptoms over time (β = −0.324, p = .002), with significant results observed up to 1 year.ConclusionsThe Perceived Immunity scale offers a valuable tool for researchers and health care providers, providing insights into the interplay between specific health beliefs and daily health. Furthermore, its validation lays the groundwork for targeted interventions that explore how health perceptions may directly influence actual physical experiences.