bluuebunny/crossref_metadata_2025_split huggingface dataset:
Production Components and Agricultural Productivity of Corn under Nitrogen Doses and Planting Times
Authors: Silva Soares Marcelo Augusto da , Silva Samuel , Teodoro Iêdo , Cantarelli Arthur Luan Dias , Rodrigues Gerlan do Nascimento , Lins Cunha Jorge Luiz Xavier , Moura Ana Beatriz de Almeida , De Moura Allan Hemerson , Moura Ana Caroline de Almeida , Filho José Gomes 
Published: December 2019

Aims: The objective of this study was to evaluate the best time for planting and nitrogen dose during the dry season that provides better yield to corn crop in the Alagoas Coastal Tablelands region.
Study Design: The experimental design was in randomized blocks, in the split plot scheme with four repetitions.
Place and Duration of Study: The experiment was developed at the Center of Agrarian Sciences of the Federal University of Alagoas in 2016.
Methodology: The plots consisted of 20 lines with seven meters in length and received the four sowing seasons (E1: 28/05/16, E2: 11/06/16, E3: 25/06/16, E4: 22/07/16). The subplots contained 5 lines of 7 meters each and received the nitrogen doses (0, 75, 150 and 225 kg ha-1). The variables analyzed were: Number of grains per ear (NGE), grain mass per ear (GME) and agricultural yield obtained from the weighing of all grains harvested in the useful area of each plot.
Results: The variables agricultural productivity and number of grains per ear of corn adjusted to the quadratic regression model, while for the mass of 1,000 grains the linear was better. Grain mass per cob, number of grains per cob, weight of 1,000 grains and yield are influenced by nitrogen rates. The E1 season was the one that provided the highest grain mass per turn (235 g), number of grains per ear (675) and agricultural yield (9.6 t ha-1). For the mass of 1,000 grains, season E2 obtained the highest result (263 g).
Conclusion: Maximum corn yield can be achieved by applying 209 kg ha-1 of N, which corresponds to a yield of 9.55 t ha-1 if planted until 06/11/16.
Development and Evaluation of a Drip Irrigation System in Southeastern Nigeria
Authors: Nwachukwu C. P. , Orakwe L. C. , Okoye N. M. 
Published: December 2019

Extreme climatic factors (temperature, precipitation etc) which at times lead to drought and flooding affect crop yield negatively. In this study, a PVC drip irrigation was developed and the irrigation parameters were evaluated in a farmland with three tillage methods (conventional tillage, conservative tillage and no tillage). The irrigation treatments comprised of three levels of irrigation (50% Management allowable depletion, 30% management allowable depletion and 10% management allowable depletion). Different irrigation parameters were evaluated for different crop growth stages, different soil treatments and different soil depths (0-25 cm, 25-50, 50-75 and 75-100 cm depths).
The field capacity was determined at -0.01MPa, from the result, the field capacity was minimum at no tillage (0.07 cm3/cm3, 0.11 cm3/cm3, 0.12 cm3/cm3, and 0.14 cm3/cm3) for soil depths 0-25 cm, 25-50 cm, 50-75 cm and 75-100 cm respectively, for conservative tillage (0.11 cm3/cm3, 0.11 cm3/cm3, 0.11 cm3/cm3, 0.14 cm3/cm3) for 0-25 cm, 25-50 cm, 50-75 cm and 75-100 cm soil depths respectively and conventional tillage (0.09 cm3/cm3, 0.13 cm3/cm3, 0.15 cm3/cm3, 0.17 cm3/cm3) for 0-25 cm, 25-50 cm, 50-75 cm and 75-100 cm soil depths respectively.
The permanent wilting point was determined at -1.5MPa, from the result, permanent wilting point increased with increase in soil depth in conventional tillage and no tillage with PWP of 0.01 cm3/cm3, 0.05 cm3/cm3, 0.09 cm3/cm3 and 0.11 cm3/cm3 at 0-25 cm, 25-50 cm, 50-75 cm and 75-100 cm soil depths respectively for conventional tillage and PWP of 0.02 cm3/cm3, 0.05 cm3cm3, 0.05 cm3/cm3 and 0.08 cm3/cm3 at 0-25 cm, 25-50 cm, 50-75 cm and 75-100 cm soil depths respectively for no tillage.
The average net irrigation was found to be 1.2 cm, 1.56 cm and 1.95 cm for conventional tillage, conservative tillage and no tillage respectively, while the average gross irrigation was found to be 1.7 cm, 1.7 cm and 2.1 cm for conventional tillage, conservative tillage and no tillage respectively.
Statistical analysis of net and gross irrigation gave a coefficient of determination of 0.99 and p-value at 0.05 was significant with a value of 0.00007.
Attitudes Study of Students and Staff of Nursing about Euthanasia in Behbahan City, 2018
Authors: Rafi Alireza , Khalili Sanaz , Naeimi Samaneh , Akbari Fakhridokht , Moradi Najmeh , Jamshidi Zeinab , Hadi Fereshteh , Mohseni Leila Amir , Karami Azam 
Published: December 2019

Introduction: Nursing students are part of a clinical teaching team in the course of education. And it is important to examine their attitude toward euthanasia. Investigating the attitude of nursing students towards euthanasia has always been welcomed by researchers. These studies often indicate a lack of acceptance of euthanasia among nurses, but different percentages of opposition to euthanasia have been reported. This study aimed to determine the attitudes study of students and staff of nursing about euthanasia in Behbahan city in 2018.
Materials and Methods: This descriptive-analytical study was conducted to investigate the euthanasia attitude among nursing staff and students in 2018. The study population is nurses and nursing students of Behbahan city. Population volume was 187 in Behbahan hospital staff and 117 students respectively, that with Cochran's formula with 95% confidence interval was 126 and 83 respectively (z: equal 1.96 p=q=0.5 d=0.5). Students were selected from semesters 4 to 8 in order to understand students correctly. Data were analyzed by SPSS software version 22 and statistical methods including: mean, frequency, T-test, Chi-Square, multiple regression test and significance level p <0.05 was used.
Results: 107 nurses and 83 nursing students participated in this study. The mean age of participants was 27 years. Multiple regression was used to examine the relationship between the dimensions of euthanasia and demographic variables. Multiple regression results showed that naturalistic beliefs were significantly different between the two groups of nurses and students (p-value = 0.021). There was no significant difference between other aspects of euthanasia attitude in nurses and students. There were also significant differences between the two groups of men in terms of practical considerations (p-value=0.048).
Conclusion: Knowing the attitudes of nurses in a community towards the issue of euthanasia can be an effective step towards a better plan for improving the care of patients with euthanasia. The results of this study showed that naturalistic beliefs were significantly different between the two groups of nurses and students. But there was no significant difference between other aspects of euthanasia attitude and nurses and students; There were also significant differences in the practical considerations between the two groups of men. It is necessary to improve the knowledge of nurses in this field.
Decapentaplegic signaling regulates Wingless ligand production and target activation during Drosophila wing development
Authors: Li Yunlong , Zhang Fengchao , Jiang Na , Liu Tong , Shen Jie , Zhang Junzheng 
Published: December 2019

The Decapentaplegic (Dpp) and Wingless (Wg) signaling pathways are essential for animal development. However, how these two signals are integrated in distinct tissues is not fully understood. Here, we describe a novel mode of Dpp‐Wg crosstalk during Drosophila wing development. We show that the canonical Dpp signaling is required for Wg target gene activation. In addition, Dpp signaling inhibits the transcription of wg through the schnurri (shn) repressor complex. A Dpp‐responsive shn/pMad/Med silencer element (SSE) is identified in the genomic loci of the wg gene. ChIP analysis suggests that shn interacts with this element in vivo. Our findings support a model in which Dpp signaling plays a dual role in transcriptional regulation of both the wg gene and downstream targets.
RARS1‐related hypomyelinating leukodystrophy: Expanding the spectrum
Authors: Mendes Marisa I. , Green Lydia M. C. , Bertini Enrico , Tonduti Davide , Aiello Chiara , Smith Desiree , Salsano Ettore , Beerepoot Shanice , Hertecant Jozef , von Spiczak Sarah , Livingston John H. , Emrick Lisa , Fraser Jamie , Russell Laura , Bernard Genevieve , Magri Stefania , Di Bella Daniela , Taroni Franco , Koenig Mary K. , Moroni Isabella , Cappuccio Gerarda , Brunetti‐Pierri Nicola , Rhee Jullie , Mendelsohn Bryce A. , Helbig Ingo , Helbig Katherine , Muhle Hiltrud , Ismayl Omar , Vanderver Adeline L. , Salomons Gajja S. , van der Knaap Marjo S. , Wolf Nicole I. 
Published: December 2019

AbstractObjectiveBiallelic variants in RARS1, encoding the cytoplasmic tRNA synthetase for arginine (ArgRS), cause a hypomyelinating leukodystrophy. This study aimed to investigate clinical, neuroradiological and genetic features of patients with RARS1‐related disease, and to identify possible genotype‐phenotype relationships.MethodsWe performed a multinational cross‐sectional survey among 20 patients with biallelic RARS1 variants identified by next‐generation sequencing techniques. Clinical data, brain MRI findings and genetic results were analyzed. Additionally, ArgRS activity was measured in fibroblasts of four patients, and translation of long and short ArgRS isoforms was quantified by western blot.ResultsClinical presentation ranged from severe (onset in the first 3 months, usually with refractory epilepsy and early brain atrophy), to intermediate (onset in the first year with nystagmus and spasticity), and mild (onset around or after 12 months with minimal cognitive impairment and preserved independent walking). The most frequent RARS1 variant, c.5A>G, led to mild or intermediate phenotypes, whereas truncating variants and variants affecting amino acids close to the ArgRS active centre led to severe phenotypes. ArgRS activity was significantly reduced in three patients with intermediate and severe phenotypes; in a fourth patient with intermediate to severe presentation, we measured normal ArgRS activity, but found translation mainly of the short instead of the long ArgRS isoform.InterpretationVariants in RARS1 impair ArgRS activity and do not only lead to a classic hypomyelination presentation with nystagmus and spasticity, but to a wide spectrum, ranging from severe, early‐onset epileptic encephalopathy with brain atrophy to mild disease with relatively preserved myelination.
Roles of Postdiagnosis Accumulation of Morbidities and Lifestyle Changes in Excess Total and Cause‐Specific Mortality Risk in Rheumatoid Arthritis
Authors: Yoshida Kazuki , Lin Tzu‐Chieh , Wei Melissa Y. , Malspeis Susan , Chu Su H. , Camargo Carlos A. , Raby Benjamin A. , Choi Hyon K. , Tedeschi Sara K. , Barbhaiya Medha , Lu Bing , Costenbader Karen H. , Karlson Elizabeth W. , Sparks Jeffrey A. 
Published: December 2019

ObjectiveTo elucidate how postdiagnosis multimorbidity and lifestyle changes contribute to the excess mortality of rheumatoid arthritis (RA).MethodsWe performed a matched cohort study among women in the Nurses’ Health Study (1976–2018). We identified women with incident RA and matched each by age and year to 10 non‐RA comparators at the RA diagnosis index date. Specific causes of death were ascertained via death certificates and medical record review. Lifestyle and morbidity factors were reported biennially; 61 chronic conditions were combined into the Multimorbidity Weighted Index (MWI). After adjusting for baseline confounders, we used inverse probability weighting analysis to examine the mediating influence of postindex MWI scores and lifestyle factors on total, cardiovascular, and respiratory mortality, comparing women with RA to their matched comparators.ResultsWe identified 1,007 patients with incident RA and matched them to 10,070 non‐RA comparators. After adjusting for preindex confounders, we found that hazard ratios (HRs) and 95% confidence intervals (95% CIs) were higher for total mortality (HR 1.46 [95% CI 1.32, 1.62]), as well as cardiovascular (HR 1.54 [95% CI 1.22, 1.94]) and respiratory (HR 2.75 [95% CI 2.05, 3.71]) mortality in patients with RA compared to non‐RA comparators. Adjusting for postindex lifestyle factors (physical activity, body mass index, diet, smoking) attenuated but did not substantially account for this excess RA mortality. After additional adjustment for postindex MWI scores, patients with RA had HRs of 1.18 (95% CI 1.05, 1.32) for total, 1.19 (95% CI 0.94, 1.51) for cardiovascular, and 1.93 (95% CI 1.42, 2.62) for respiratory mortality.ConclusionWe found that MWI scores substantially accounted for the excess total and cardiovascular mortality among women with RA. This finding underscores the importance of monitoring for the total disease burden as a whole in monitoring patients with RA.
Adiposity and Physical Activity as Risk Factors for Developing Psoriatic Arthritis: Longitudinal Data From a Population‐Based Study in Norway
Authors: Thomsen Ruth S. , Nilsen Tom I. L. , Haugeberg Glenn , Gulati Agnete M. , Kavanaugh Arthur , Hoff Mari 
Published: December 2019

ObjectiveAdiposity is prevalent among patients with psoriatic arthritis (PsA). However, the temporal relation is unclear. The present study was undertaken to investigate whether adiposity and body fat distribution are related to the risk of developing PsA, and whether physical activity could modify the possible risk.MethodsWe included 36,626 women and men from the Norwegian Nord‐Trøndelag Health Study without diagnosed PsA at baseline from 1995 to 1997. Cox regression analysis was used to estimate adjusted hazard ratios (HRs) with 95% confidence intervals (95% CIs) of incident PsA at follow‐up from 2006 to 2008.ResultsDuring follow‐up, 185 new cases of PsA were reported. Increases of 1 SD in body mass index (BMI) (4.2 and 3.5 kg/m2 for women and men, respectively) and waist circumference (10.8 and 8.6 cm, respectively) were associated with HRs of 1.40 (95% CI 1.24, 1.58) and 1.48 (95% CI 1.31, 1.68), respectively. Compared to individuals of normal weight, obese individuals had an HR of 2.46 (95% CI 1.65, 3.68), and overweight individuals had an HR of 1.41 (95% CI 1.00, 1.99). Comparing extreme quartiles of waist circumference yielded an HR of 2.63 (95% CI 1.73, 3.99). In analyses of combined effects using a BMI of <25 kg/m2 and high physical activity as reference, a BMI of ≥25 kg/m2 was associated with HRs of 2.06 (95% CI 1.18, 3.58) and 1.53 (95% CI 0.80, 2.91) among those with low and high physical activity levels, respectively. Corresponding HRs for high waist circumference and physical activity were 2.25 (95% CI 1.40, 1.63) and 1.85 (95% CI 0.95, 3.50).ConclusionThe results suggest that adiposity, particularly central obesity, is associated with increased risk of incident PsA. Although there was no clear modifying effect of physical activity, high levels of physical activity reduced the risk of PsA, regardless of BMI.
Protein and Hydrophobic Association‐Regulated Hydrogels with Adhesive Adjustability in Different Materials
Authors: Xu Jianyu , Gao Guanghui , Duan Lijie , Sun Guoxing 
Published: December 2019

AbstractAdhesiveness, as one of the basic properties of hydrogels, has attracted much attention in the fields of medical bandage, flexible wearable device, and electrolyte. However, the adhesive property is difficult to be adjusted on the surfaces of different substrates. Herein, casein, a model of protein, and a hydrophobic monomer (2‐methoxyethyl acrylate, MEA) are successfully introduced into polyacrylamide (pAAm) hydrogels. As a result, the pAAm–MEA–Casein hydrogels exhibited not only good mechanical property based on the multiple physical crosslinking, but also excellent adhesive adjustability for different hydrophobic and hydrophilic surfaces through the regulation of hydrophobic interactions. The tensile stress of pAAm–MEA10–Casein37.5 hydrogels can achieve 258 kPa with a strain of around 2200%. The adhesive performance is always kept after 40 times repeatedly bonding to the silicon rubber surface, and the interfacial toughness is around 115.22 J m−2. Moreover, the adjustable bonding of the hydrogel to the hydrophilic and hydrophobic materials can be achieved by changing the content of hydrophobic segments. This protein‐driven hydrophobic association strategy would open a new approach to design a new generation of adjustable adhesion soft materials for biomedical engineering.
Metasurfaces Composed of Plasmonic Molecules: Hybridization Between Parallel and Orthogonal Surface Lattice Resonances
Authors: Liu Shao‐Ding , Yue Peng , Zhang Shi , Wang Mingshan , Dai Hongwei , Chen Yiqin , Nie Zhong‐Quan , Cui Yanxia , Han Jun‐Bo , Duan Huigao 
Published: December 2019

AbstractMultiple surface lattice resonances suppress radiative losses effectively around several spectral positions, thereby enhancing the light‐matter interactions and making them promising for multiwavelength related applications, and it is important to develop reliable methods to generate multiple lattice resonances. In analogy to natural materials composed of various kinds of molecules, this study proposed to construct metasurfaces with plasmonic artificial molecules, which represent distinct collective responses compared with that of single nanoparticles. It is shown that sharp multiple surface lattice resonances are excited due to the coupling between the localized resonances of plasmonic trimer molecules and the Rayleigh anomalies of the array, and there is a rarely observed parallel lattice resonance caused by the formation of equivalent dipoles perpendicular to the polarization. Particularly, even though the parallel mode is weak, a pronounced anticrossing behavior due to the hybridization with the orthogonal mode occurs when the resonance energies are approaching to each other, which results in two hybridized eigenmodes that possess both characteristics of parallel and orthogonal Rayleigh anomalies. Considering the excitation of the lattice resonances in asymmetric environments, the flexible tunability, and the ability to tailor the collective responses, metasurfaces constructed with artificial molecules are promising platforms to design ultrafast and compact photonic devices.
Impact of MYD88L265P mutation status on histological transformation of Waldenström Macroglobulinemia
Authors: Zanwar Saurabh , Abeykoon Jithma P. , Durot Eric , King Rebecca , Perez Burbano Gabriela E. , Kumar Shaji , Gertz Morie A. , Quinquenel Anne , Delmer Alain , Gonsalves Wilson , Cornillet‐Lefebvre Pascale , He Rong , Warsame Rahma , Buadi Francis K. , Novak Anne J. , Greipp Patricia T. , Inwards David , Habermann Thomas M. , Micallef Ivana , Go Ronald , Muchtar Eli , Kourelis Taxiarchis , Dispenzieri Angela , Lacy Martha Q. , Dingli David , Nowakowski Grzegorz , Thompson Carrie A. , Johnston Patrick , Thanarajasingam Gita , Bennani N. Nora , Witzig Thomas E. , Villasboas Jose , Leung Nelson , Lin Yi , Kyle Robert A. , Rajkumar S. Vincent , Ansell Stephen M. , Le‐Rademacher Jennifer G. , Kapoor Prashant 
Published: December 2019

AbstractHistological transformation in Waldenström macroglobulinemia (WM) is an uncommon complication, with limited data, particularly regarding the impact of MYD88
L265P mutation on transformation. We examined risk factors and outcomes associated with transformation in WM, highlighting the role of MYD88
L265P mutation. Patients with WM seen at Mayo Clinic, Rochester, USA and University Hospital of Reims, France, between 01/01/1996 and December 31, 2017 were included; 50 (4.3%) of 1147 patients transformed to a high‐grade lymphoma, with median time‐to‐transformation of 4.5 (range 0‐21) years in the transformed cohort. The MYD88
L265P mutation status was known in 435/1147 (38%) patients (406 with non‐transformed WM and 29 patients in transformed cohort). On multivariate analysis, MYD88
WT status alone was an independent predictor of transformation (odds ratio, 7[95%CI: 2.1‐23]; P = .003). Additionally, the MYD88
WT status was independently associated with shorter time‐to‐transformation (HR 7.9 [95%CI: 2.3‐27; P = .001]), with a 5‐year transformation rate of 16% for MYD88
WT vs 2.8% with MYD88
L265P mutated patients. Patients with transformation demonstrated a significant increase in risk of death compared to patients who did not transform (HR 5.075; 95%CI: 3.8‐6.8; P < .001). In conclusion, the MYD88
WT status is an independent predictor of transformation and associated with a shorter time‐to‐transformation. Additionally, transformation conferred an inferior overall survival in patients with WM.
Morphology‐Reserved Synthesis of Discrete Nanosheets of CuO@SAPO‐34 and Pore Mouth Catalysis for One‐Pot Oxidation of Cyclohexane
Authors: Guo Xiangke , Xu Mengxia , She Minyi , Zhu Yan , Shi Taotao , Chen Zhaoxu , Peng Luming , Guo Xuefeng , Lin Ming , Ding Weiping 
Published: December 2019

AbstractDiscrete nanosheets of silicon‐doped AlPO4 molecular sieves (SAPO‐34) with a thickness of ≈7 nm have been prepared through morphology‐reserved synthesis with a lamellar aluminum phosphate as precursor. Cages of the nanosheets are in situ incorporated with copper oxide clusters. The CuO@SAPO‐34 nanosheets exhibit a large external surface area with a high number of (010) channel pores on the surface. Due to the thin morphology, copper oxide clusters occupy the outmost cages with a probability >50 %. The distinctive configuration facilitates a new concept of pore mouth catalysis, i.e., reactant molecules larger than the pores cannot enter the interior of the molecular sieves but can interact with the CuO clusters at “the mouth” of the pore. In heterogeneous catalysis, CuO@SAPO‐34 nanosheets have shown top performance in one‐pot oxidation of cyclohexane to adipic acid by O2, a key compound for the manufacture of nylon‐66, which is so far produced using non‐green nitric acid oxidation.
Suprakolloidale Selbstorganisation von bivalenten Janus‐3D‐DNA‐Origami über programmierbare, multivalente Wirt/Gast‐Wechselwirkungen
Authors: Loescher Sebastian , Walther Andreas 
Published: December 2019

AbstractWir stellen zweiwertige 3D‐DNA‐Origami‐Quader als monodisperse Kolloide vor und nutzen ihre Fähigkeit der molekularen Erkennung, um räumlich genau angeordnete Interaktionsmuster und eine definierte Anzahl supramolekularer Bindungsmotive zu erzeugen. Wir zeigen, dass Adamantan/β‐Cyclodextrin‐Wirt/Gast‐Einschlusskomplexe mit mäßiger Assoziationsstärke eine effiziente suprakolloidale Fibrillierung selbst bei hoher Verdünnung der 3D‐DNA‐Origami aufgrund kooperativer Multivalenz ermöglichen. Details der Assemblierung von Janus‐ und Nicht‐Janus‐3D‐DNA‐Origami zu suprakolloidalen Homo‐ und Heterofibrillen in Bezug auf Multivalenzeffekte, elektrostatische Abstoßung und Stöchiometrie werden aufgezeigt. Wir schlagen vor, dass die Vereinigung von 3D‐DNA‐Origami mit kolloidaler Selbstorganisation und supramolekularen Motiven neue Synergien an der Schnittstelle dieser Disziplinen bietet, um Multivalenzeffekte besser zu verstehen, strukturelle Komplexität zu fördern und die DNA‐Nanowissenschaften um Mechanismen zu erweitern, die Nicht‐DNA‐Assemblierung und Schaltung ergänzen.
Chiral N‐Heterocyclic Carbene Ligands Enable Asymmetric C−H Bond Functionalization
Authors: Thongpaen Jompol , Manguin Romane , Baslé Olivier 
Published: December 2019

AbstractThe asymmetric functionalization of C−H bond is a particularly valuable approach for the production of enantioenriched chiral organic compounds. Chiral N‐heterocyclic carbene (NHC) ligands have become ubiquitous in enantioselective transition‐metal catalysis. Conversely, the use of chiral NHC ligands in metal‐catalyzed asymmetric C−H bond functionalization is still at an early stage. This minireview highlights all the developments and the new advances in this rapidly evolving research area.