bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hematological Profiles in Hemoglobinopathy Patients in South Western Nepal
Authors: Gautam Narayan , Jayan Archana , Dubey Raju Kumar , Jha Amit Chandra , Deshar Sunkeshari , Tamang Binaya , Pokhrel Buddhi Raj , Phuyal Reena , Shah Anita , Kaphle Raju 
Published: July 2020

INTRODUCTION: Homozygous inheritance of the hemoglobin results in sickle cell anemia (SCA), heterozygous inheritance results in sickle cell trait (SCT). Sickle cell anemia and β-thalasemia (β-TT) have been a major health threat for the tharu living in the South-Western Terai of Nepal. This study is carried out to apply and optimise the phenotypic method and haematological profile to characterise the SCT, SCA and β-TT from suspected tharu community dwellers.
MATERIAL AND METHODS: We enrolled 100 suspected cases of hemoglobinopathies of 12-14 years children and ≥15 years adults tharu community dwellers from Dang, Kapilvastu, Nepalgunj, Rupandehi and Nawalparasi of South-Western Nepal from May 2018 to November 2018. Five mililitre of blood was collected in EDTA vial and transported to the laboratory maintaining cold chain. The hematological profile was recorded after investigations. The hemolysate from blood samples were subjected to phenotypic testing by adopting cellulose acetate electrophoresis at pH 8.6.
RESULTS: Our result showed the commonest hemoglobinopathy was SCT (38%) followed by β-TT (21%) and SCA (5%). Males were more affected with SCA (60%) while that of females were most affected with β-TT (57.1%). Only 44.7% females were affected with SCT while 42.9% males were affected with β-TT. The significant difference in mean was observed in Hb level (p=0.0001), RBC (p=0.004), MCHC (p=0.015) and RDW (p=0.028) whereas the non-significant difference in mean was observed for glucose 6 phosphate dehydrogenase (G6PD) level (p=0.063) in hemoglobinopathy patients.
CONCLUSION: Most cases develop severe type of anemia as shown by change in hematological parameters. This information could advocate for timely counselling before constellation of associated condition appeared in hemoglobinopathy patients.
Metode Location Based Service Dalam Mengurangi Resiko Tersesat Saat Pendakian Gunung Menggunakan Global Positioning System (GPS)
Authors: Nugroho Danan Rifandi , Ramdhani Asep , Putra Tri Dharma 
Published: July 2020

Abstract

Climbing in Indonesia from year to year has increased the demand. More and more climbers are interested in this activity but increasingly also accidents that occur in the mountain due to lack of knowledge and discipline of climbers. The mountaineering guide app is made to help climbers to plan preparations before climbing and while climbing the mountains, this app also features a mountain position layout and path from basecamp, climbing posts to the top, and can request evacuation requests at TimSAR. By using the technology of Global Positioning System and Location Based Service climbers can easily find the point where it is located, and can minimize accidents and even death that can occur in the mountain.

Keywords: Mountaineer, Location Based Service, Global Positioning System, Mountain Climbing Guide.

Abstrak

Pendakian di Indonesia dari tahun ke tahun mengalami peningkatan peminatnya. Semakin banyak pendaki yang meminati kegiatan ini tetapi semakin bertambah pula kecelakaan yang terjadi di gunung akibat kurangnya pengetahuan dan kedisiplinan pendaki. Aplikasi panduan mendaki gunung dibuat untuk membantu para pendaki untuk merencanakan persiapan sebelum mendaki dan saat mendaki gunung, aplikasi ini juga dilengkapi dengan tata letak posisi gunung dan jalur dari basecamp, pos-pos pendakian sampai ke puncak, dan dapat meminta permintaan evakuasi pada TimSAR. Dengan menggunakan teknologi Global Positioning System dan Location Based Service pendaki dapat dengan mudah mencari titik posisinya berada, dan dapat meminimalisir kecelakaan bahkan kematian yang dapat terjadi di gunung.

Kata kunci: Pendaki Gunung, Location Based Service, Global Positioning System, Panduan Mendaki Gunung.
Pembentukan Badan Usaha Milik Desa Di Sumberanyar Pasuruan Untuk Peningkatan Kesejahteraan Masyarakat
Authors: Adam Haidar , Ristawati Rosa , Ramadhanti Syifa , Nugraha Xavier 
Published: July 2020

Dalam rangka meningkatakan kesejahteraan di desa-desa, Undang-Undang Nomor 6 Tahun 2014 tentang Desa memberikan sebuah instrument bagi Desa untuk melakukan kegiatan usaha melalui Badan Usaha Milik Desa. Penelitian ini bertujuan untuk mengenalkan Badan Usaha Milik Desa kepada masyrakat di Desa Sumberanyar, Kecamatan Nguling, Kabupaten Pasuruan dalam rangka meiningkatkan kesejahteraan di desa tersebut. Penelitian di awali dengan Assesement Masalah dan Kebutuhan Desa, Focus Group Discussion, dan diakhiri dengan Legalitas BUMDes. Dari penelitian ini menunjukan, bahwa masyrakat di Desa Sumberanyar, Kecamatan Nguling, Kabupaten Pasuruan memiliki antusiasme yang tinggi terhadap pembentukan Badan Usaha Milik Desa di desa tersebut dan berharap kedepannya terdapat pelatihan-pelatihan terkait dengan pengurusan Badan Usaha Milik Desa tersebut agar pengurus-pengurus yang ada dapat menjalankan fungsi dan tugasnya dengan baik
PERSEPSI DAN HARAPAN PEMUSTAKA TERHADAP PENGEMBANGAN SISTEM MANAJEMEN PERPUSTAKAAN UIN RADEN INTAN DI ERA COVID 19 MENUJU NEW NORMAL LIFESTYLE
Authors: Rodiyah  , Inah Indrakasih Rohai 
Published: July 2020

The development of information and communication technology is very fast affecting various fields of life and professions. The changes that were accompanied by the potential offer of telematics also caused a paradigm shift in the field of higher education. The paradigm changes include E-Learning, E-Research, and information literacy which requires libraries to develop to support the smooth running of education, research and society.
This reserach uses participatory observation method. The subjects of this study were active library users of UIN Raden Intan Lampung. Data collection in this research is through questionnaire surveys, interviews, and document studies.
The results of the study are the perceptions and expectations of users to the development of Raden Intan Library in the digital era is the merging of the Four building concepts: the concept of green library, Academic Library, Supermarket Library and Home Library.
Keywords: Digital Library, Perception and Expectations, visitors of library, Library Management.
TRAVELERS’ MOTIVATIONS TO TRAVEL ABROAD DURING COVID 19 OUTBREAK
Authors: Rachmawati Iin , Shishido Kumiko 
Published: July 2020

Purpose: The purpose of this study is to know the impact of Covid 19 to travel desire of those Indonesian travelers to travel abroad.
Research methods: This study used mix methods to give details on the data which was produced by the media related to this corona virus or more recently popular as Covid 19. The data has been gathered in the form of numbers and tables about the spread of Covid 19 over the world, about the victims infected by this virus over the last three months, as well as about the direct impact on the tourism sector for Indonesian travelers to travel abroad. Then, the data has explained descriptively in order to get deeper understanding about Covid 19 facts and travel impact towards Indonesian travelers.
Results and discussions: The result showed that the spreading has happened almost in the entire world with most infected area is around Asia and Europe with the total case of 245,612. The death victims are 10,048 people and the survivors are 88,437 people. The data statistics are also showed for about 78% Indonesian travelers chose to cancel and reschedule their travel plans to abroad as well as 22% of them still have no idea what to do with their future trip.
Conclusion: It can be concluded that Covid 19 has hit the tourism sector in Indonesia
Pengujian Black Box pada Aplikasi Penjualan Berbasis Website dengan PHP MySQL Kedai Kopi.Net Menggunakan Teknik Boundary Value Analysis
Authors: Soejono Daniel Dadan Wiguna , Candra Dedek Rahmat , Rosandi Dedi , Putra Rizki Rahma , Nurfaidzin Yoga , Ardiansyah Hendri 
Published: July 2020

Kopi.Net shop application is an applications created and designed in the hope that it can provide information about every product in Kopi.Net shot online, but it cannot be used in general because there are still problems so testing needs to be done in order to reduce the level of failure or error which can cause losses to the store’s selling activities. Applications that have already been designed must be tested first, in the coffee shop application testing using the boundary value analysis and validation method, validation is a process to the check whether the application has reached the desired application standard. In proof, a data that is not accordance with the database. As an example, stock data will become uncertain or exceed the capacity created. That way it can cause harm to the coffee shop application. Therefore, it requires repairing and testing data validation more accurately. So that it can help the owner of the coffee shop application in accurate data stock data. Testing applications that are designed must be tested before the application is made must go through testing to ensure applications that have been made must pass through the stages of testing so that the application has good quality. Testing can be said to be good if it finds a program failure that is difficult to find. There are many black box testing methods, on this occasion the examiner uses the boundary value analysis method. This boundary value analysis method tests the number of maximum limits and the number of suitable minimum limits and find valid result. Testing is quite maximum for the Kedai Kopi.Net application. The initial process in testing this application is to provide a definition of what will be tested, create a test framework, and choose test materials. And ensure the maximum and minimum amount in accordance with the structure of the database, as well as making the result of the documented test results and can draw conclusions based on test result. Kedai Kopi.Net application can be used after the test is complete and can be used well, and is said to be successful if all errors can be known and corrected before general use.
EKSISTENSI PENGADILAN TINDAK PIDANA KORUPSI MENURUT UNDANGUNDANG NOMOR 46 TAHUN 2009 TENTANG PENGADILAN TINDAK PIDANA KORUPSI TERHADAP PEMBERANTASAN KORUPSI
Authors: Prastiwi Dian Eka 
Published: July 2020

Korupsi merurupakan faktor penghambat bagi perkembangan demokrasi, menghambat pelaksanaan tugas lembaga-lembaga public serta penyalahgunaan sumber daya yang dimiliki baik sumber daya alam maupun sumber daya manusia secara optimal untuk kesejahteraan masyarakat. Perangkat hukum mulai dari Undang-Undang Anti Korupsi, Lembaga Anti Korupsi atau Komisi Pemberantasan Korupsi (KPK), dan Pengadilan Khusu yang menangani kasus korupsi yang disebut dengan Pengadilan Tindak Pidana Korupsi. Dari keseluruhan masalah yang ada Pengadilan Tindak Pidana Korupsi dibentuk untuk menyelesaikan kasus Tindak Pidana Korupsi yang termasuk dalam kejahatan ExtraOrdinary Crime. Kedudukan, kewenangan dan tujuan dibentuknya Pengadilan Tindak Pidana Korupsi ini diatur dalam Undang-Undang Nomor 46 Tahun 2009 tentang Pengadilan Tindak Pidana Korupsi. Adanya pengadilanTindak Pidana Korupsi ini dapat membawa hal posistif karena dapat meningkatkan kepercayaan masyarakat pada lembaga hukum yang ada di Indonesia.
PERAN DEWAN PENGAWAS SYARIAH DALAM PENCAPAIAN MAQASID SYARIAH PADA BANK SYARIAH
Authors: Kurrohman Taufik 
Published: July 2020

Dewan pengawas syariah memiliki peran yang sentral dan menentukan di dalam pencapaian maqasid syariah, yaitu pada pencapaian yang dimaksudkan syara menjaga agama dan fokusnya pada kemaslahatan harta. Dalam tatanan praktisnya dewan pengawas syariah mempunyai tugas dan fungsi sebagai penegak prinsip-prinsip syariah yang bermuara pada pencapaian maqasid syariah. Terdapat kendala yang substansial yang dihadapi oleh dewan pengawas syariah baik secara struktural kelembagaan maupun secara praktik yang akan mempengaruhi tingkat ketercapaian maqasid syariah. Penulisan ini memfokuskan pada permasalahan peran dewan pengawas syariah dalam pencapaian maqasid syariah pada bank syariah serta hambatan dalam pencapaian tersebut. Metode penelitian dalam penulisan ini normatif kualitatif dengan penguatan pada data emperis. Hasil penelitian ini menunjukan pertama, peran dewan syariah dalam pencapaian maqasid syariah pada bank syariah sangat menentukan karena sebagai penjaga syariah compliance, kedua, hambatan yang dihadapi secara kelembagaan tidak bersifat idependen dan secara praktis tidak dapat mengeksekusi secara kelembagaan.
PENERAPAN PENYELESAIAN KREDIT MACET DENGAN RESTRUKTURISASI BERDASARKAN PASAL 21 PERATURAN OTORITAS JASA KEUANGAN NOMOR: 33/POJK.03/2018 TENTANG RESTRUKTURISASI (Studi Kasus di BPR Lestari Jakarta Barat)
Authors: Soleha Soleha 
Published: July 2020

Kewajiban nasabah Debitur dalam perjanjian kredit adalah melunasi hutangnya dalam jangka waktu tertentu dengan sejumlah nominal yang disertai bunga. Namun demikian adanya faktor intern dan/atau ekstern, yang menyebabkan Debitur mengalami kredit macet, sehingga tidak bisa memenuhi prestasi yang telah dijanjikan sebagaimana terdapat dalam perjanjian kredit. Apabila nasabah Debitur yang mengalami kredit macet dan jika masih dimungkinkan untuk berprestasi lagi dalam memenuhi kewajibannya, maka bank biasanya akan melakukan penyelesaian secara baik yaitu menolong nasabah yang sedang mengalami kesulitan dengan melakukan penyelamatan. Adapun upaya penyelamatan yang dimaksud dapat berupa, penjadawalan kembali (rescheduling), persyaratan kembali (reconditioning), dan penataan kembali (restructuring). Tujuan penelitian ini adalah untuk menganalisis penerapan restrukturisasi kredit macet yang diatur dalam Pasal 21 Peraturan Otoritas Jasa Keuangan Nomor : 33/POJK.03/2018 dalam pelaksanaannya di BPR Lestari Jakarta Barat dan untuk mengetahui hambatan-hambatan dalam penerapan restrukturisasi kredit macet di BPR Lestari Jakarta Barat sesuai dengan Pasal 21 yang diatur dalam Peraturan Otoritas Jasa Keuangan Nomor: 33/POJK.03/2018, dalam hal ini peneliti terjun langsung kelapangan untuk memproleh data dengan melakukan wawancara dengan Pimpinan dan Kepala bagian (Kabag) Kredit di BPR Lestari Jakarta Barat, Metode Penelitian skripsi yang digunakan, yaitu penelitian kepustakaan, maka pendekatan yang digunakan dalam penulisan skripsi ini adalah pendekatan perundang-undangan (statue approach), pendekatan konsep (conceptual approach), dan juga dengan pendekatan kasus (case approach), Berdasarkan hasil wawancara dengan Pak Enden selaku Kepala bagian (Kabag) Kredit ini bertentangan dengan kebijakan restruktur dalam butir (b) yang menerangkan bahwa pejabat atau pegawai yang ditugaskan dalam unit kerja atau pejabat yang ditunjuk untuk menangani Restrukturisasi Kredit tidak terlibat dalam proses pemberian Kredit kepada Debitur yang akan direstruktrurisasi tersebut, artinya baik itu bagian analis sebelum kredit itu dicairkan dan ketika kredit itu bermasalah itu dilakukan dengan pejabat atau pegawai yang berbeda, untuk saat ini di BPR Lestari Jakarta Barat itu masih dilakukan dengan pejabat atau pegawai yang sama, seharusnya untuk menjaga sikap konsistensi berdasarkan jabatan ini dilakukan dengan pejabat atau pegawai yang berbeda, tujuannya agar ada perbandingan dan bisa dievaluasi apabila ada koreksi.
Essence and Content of Legal Settlement and Tax Amnesty
Authors: Syromiatnikova M. S. 
Published: July 2020

The article is focused on defining the essence and content of legal settlement and tax amnesty. The main features and areas of applying legal settlement in various fields of law have been studied. The legal principles of reaching a legal settlement in civil, labor, tax and criminal procedural law have been studied. The author has suggested own definition of a legal settlement. The content of a legal settlement has been defined as the achievement of mutual concessions of the parties within the legal norms.
The main features, procedure and grounds for tax amnesty have been determined. The author has provided specific measures that can be taken under the tax amnesty. The procedure for legalization of funds and release of the perpetrator of violations of tax legislation from legal liability under the tax amnesty has been highlighted. The author has presented conclusions of researchers who studied the practice of tax amnesty in different countries. The author has suggested own definition of tax amnesty.
The diagnostic potential of microneedles in infectious diseases
Authors: Dixon Rachael V. , Lau Wing Man , Moghimi S. Moein , Ng Keng Wooi 
Published: July 2020

<img src=” https://s3.amazonaws.com/production.scholastica/article/13658/large/prnano_502020_ga.jpg?1594060131”> The coronavirus disease 2019 (COVID-19) pandemic has taught us much about our weaknesses in the management of infectious disease outbreaks. A key lesson has been the need for more effective point-of-care diagnostic tools that not only produce rapid and reliable results, but also facilitate decentralised testing to avoid overwhelming central test facilities when demand peaks in an outbreak. Microneedle devices can be inserted painlessly into the skin to detect biomolecules in the epidermal and dermal layers. They have been used to detect biomarkers both in the interstitial fluid and the capillary blood. Importantly, they are amenable to self-administration. In this article, we provide an overview of existing microneedle-based diagnostic technologies and discuss how they may be built upon to provide effective diagnostic tools for infectious diseases in general.
Rene, ADPKD e COVID-19: il doppio ruolo della fragilità renale.
Authors: Sciarrone Alibrandi Maria Teresa , Vespa Marta 
Published: July 2020

The Corona Virus Disease 19 (COVID19) is an infectious disease caused by SARS – CoV – 2 (Severe Acute Respiratory Syndrome Coronavirus 2). By now, the pandemic has already led 318000 people to their death and our knowledge of this pathogen is still in its infancy. What we know so far is that older patients suffering from different comorbidities, such as heart failure, COPD and tumors, are keener to develop severe complications from which they might perish. The role of chronic kidney disease is still not clear, though. What we do know is that CKD patients are more susceptible to infections, both viral and bacterial, compared to the main population. It has been recently highlighted that the immune response might be the real cause of damage in the lung tissues and not just the virus itself, therefore, the better the immune response, the greater the damage. Quite paradoxically, being chronically renal impaired and suffering from a delayed T-Cell response might actually be beneficial, avoiding a massive inflammatory reaction followed by SARS. According to a recent survey led by the SIN (Italian Society of Nephrology), only 2.8% of COVID patients is under hemodialysis treatment. Unfortunately, we do not have more detailed data on every single specific form of CKD. For instance, there is no clear relation between COVID19 an ADPKD. What might be inferred is the following: COVID uses the ACE2 receptors on cell membranes to “lock on “ its target. It is a well-established fact that the RAAS is more active in ADPKD patients, whether it is a matter of hyper activation or hyper-expression of ACE2 receptors it’s not clear. Also, the fact that these patients are usually on drug treatment with an ACE Inhibitor or an ARB might have some implications that are definitely worth analyzing.
THE IMPACT OF OPENING UP A TRADITIONAL CULTURE TO TOURISM DEVELOPMENT
Authors: Caecilia Caecilia , Umarjadi Utami , Hidayat Nila K. 
Published: July 2020

The Baduy Tribe is a cultured and friendly indigenous people living harmoniously in the middle of natural environment and far from the civilization. This study aims to determine the level of acceptance of opening up the Inner Baduy as a tourism destination and also to identify the impacts on the opening up the Inner Baduy to tourism development. This study use both quantitative and qualitative analysis.
The result revealed that there are three elements are used to justify the level of acceptance of the Baduy people; two showed rejections (needs and desires and opinions on opening up the Inner Baduy). This is strengthened by the result of the interviews that tribe rules and regulations do not allow the Inner Baduy to be opened up. Another finding is proven by the disadvantages that impact the host community if the Inner Baduy is opened up to tourism market. It could cause culture acculturation, a deterioration of morality, environmental damages, and also the decreased quality of local people’s language. For the regional development, the opening up of the Inner Baduy can bring advantages such as improvements of infrastructures and economic benefits. The Inner Baduy is unofficially opened for visits from the tourists but the policy to open it up to mass market depends entirely on the decision of the host community.
Penerapanan Metode Beyond Centers And Circle Time (Bcct) Pada Pendidikan Anak Usia Dini (Paud)
Authors: Robecca Julian , Sofiani Ratna Imanira , Hasti Novrini 
Published: July 2020

ABSTRACT
The golden age for a child is the age when he is 0 to 5 years old. At this age the child's physical development and brain growth optimally. Children's brain development related to intelligence requires stimulation from the surrounding environment. If stimulation from the environment is lacking, the child's intellectual development is also not optimal. To increase stimulation from an early age many Early Childhood Education (PAUD) have emerged, which is a form of educational institution which is an artificial environment that is consciously designed and planned to develop children's intelligence potential. From 2013 data, the Directorate General of Early Childhood, Non-Formal and Informal Education (PAUDNI) Bandung has 1,323 PAUD. From all of these methods there is one concept that is the benchmark in the PAUD program, namely that education must be fun and in accordance with the child's development. The BCCT method develops from the Montessori, High Scope and Region Emilio methods. The purpose of community service activities is to create teachers who can apply BCCT learning methods to students, assist teachers in the delivery of learning materials that are appropriate to the child's development, help children in the reception and absorption of learning materials, create a pleasant atmosphere in the learning process for both partners .
Key words: Early Childhood Education, Beyond Centers and Circle Time (BCCT), golden age,

ABSTRAK
Golden age bagi seorang anak adalah usia ketika dia berusia 0 hingga 5 tahun. Pada usia ini perkembangan fisik dan otak anak tumbuh secara optimal. Perkembangan otak anak yang berkaitan dengan kecerdasan membutuhkan stimulasi dari lingkungan sekitarnya. Jika stimulasi dari lingkungan kurang, perkembangan intelektual anak juga tidak optimal. Untuk meningkatkan stimulasi sejak usia dini banyak bermunculan Pendidikan Anak Usia Dini (PAUD), yaitu suatu bentuk lembaga pendidikan yang merupakan lingkungan buatan yang secara sadar dirancang dan direncanakan untuk mengembangkan potensi kecerdasan anak. Dari data tahun 2013, Direktorat Jenderal Pendidikan Anak Usia Dini, Nonformal dan Informal (PAUDNI) Bandung ada 1.323 PAUD. Dari semua metode ini ada satu konsep yang menjadi tolok ukur dalam program PAUD, yaitu bahwa pendidikan harus menyenangkan dan sesuai dengan perkembangan anak. Metode BCCT mengembang dari metode Montessori, High Scope dan Regio Emilio. Tujuan kegiatan pengabdian masyarakat adalah, menciptakan guru yang dapat menerapkan metode pembelajaran BCCT pada siswa, membantu guru dalam penyampaian materi pembelajaran yang sesuai dengan perkembangan anak, membantu anak-anak dalam penerimaan dan penyerapan bahan belajar, menciptakan suasana yang menyenangkan di proses pembelajaran pada kedua pasangan.

Kata kunci: Beyond Center Circle Time (BCCT), golden age, Pendidikan Anak Usia Dini (PAUD),