bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Pendidikan dan Latihan Terhadap Kompetensi Pegawai Di Sekretariat Dinas Bina Marga dan Bina Konstruksi Provinsi Sumatera Utara
Authors: Barus Hestita , Tarigan Usman , Angelia Nina 
Published: September 2020

Tujuan penelitian ini adalah untuk mengetahui Pengaruh Pendidikan dan Pelatihan (Diklat) Terhadap Kompetensi Kerja Pegawai di Sekretariat Dinas Bina Marga dan Bina Konstruksi Provinsi Sumatera Utara. Metode penelitian yang digunakan dalam penelitian ini adalah metode kuantitatif. Sampel penelitian ini adalah seluruh Pegawai di Dinas Bina Marga dan Bina Kontruksi yaitu sebanyak 46 orang pegawai. Teknik pengumpulan data dalam penelitian ini adalah penelitian kepustakaan, Penelitian lapangan, kuesioner, wawancara. Teknik analisis data dilakukan dengan cara Regresi Sederhana, menguji signifikan hipotesis dipergunakan rumus signifikan uji t, dan uji Koefisien Determinan. Hasil penelitian terdapat pengaruh yang positif dan signifikan antara Pendidikan dan Pelatihan (Diklat) Terhadap Kompetensi Kerja Pegawai di Sekretariat Dinas Bina Marga dan Bina Konstruksi Provinsi Sumatera Utara, Nilai t hitung variabel pendidikan dan pealtihan adalah 6,750 dan nilai t tabel 1.680 maka thitungttabel (6,7501.680) sehingga dapat disimpulkan bahwa dari variabel pendidikan dan pelatihan berpengaruh positif dan signifikan (0,0000,05) secara parsial terhadap komptensi pegawai. Adapun kesimpulan dari penelitian ini menunjukkan terdapat pengaruh yang positif dan signifikan antara Pendidikan dan Pelatihan (Diklat) Terhadap Kompetensi Kerja Pegawai di Sekretariat Dinas Bina Marga dan Bina Konstruksi Provinsi Sumatera Utara.
Book Reviews
Authors: Neyzi Leyla , Alahmad Nida , Gren Nina , Lagace Martha , Ancliffe Chelsey , Bregnbæk Susanne 
Published: September 2020

Sacrificial Limbs: Masculinity, Disability, and Political Violence in Turkey, by Salih Can Açıksöz. Berkeley: University of California Press, 2019. 272 pp. 19 illus. Paperback. ISBN 978-0-5203-0530-4.
For the Love of Humanity: The World Tribunal on Iraq, by Ayça Çubukçu. Philadelphia: University of Pennsylvania Press, 2018. 240 pp. 7 illus. Hardcover. ISBN 978-0-8122-5050-3.
Life Lived in Relief: Humanitarian Predicaments and Palestinian Refugee Politics, by Ilana Feldman. Berkeley: University of California Press, 2018. 320 pp. 20 illus. Hardcover. ISBN: 978-0-520-29963-4.
Peaceful Selves: Personhood, Nationhood, and the Post-Conflict Moment in Rwanda, by Laura Eramian. New York: Berghahn Books, 2019. 202 pp. 3 illus. Paperback. ISBN: 978-1-78920-493-3.
Counterrevolution: The Global Rise of the Far Right, by Walden Bello. Blackpoint: Fernwood Publishing, 2019. 196 pp. Paperback. ISBN: 978-1-77363-221-6.
Critique of Identity Thinking, by Michael Jackson. New York: Berghahn Books., 2019. 207 pp. Hardcover. ISBN 978-1-78920-282-3.
Pengaruh Ukuran Perusahaan Terhadap Audit Delay Dengan Return On Asset Sebagai Variabel Mediasi Pada Sub Sektor Perbankan Tahun 2017-2018
Authors: Caroline Verawaty , Hutabarat Francis 
Published: September 2020

Adapun tujuan dari penelitian ini di adakan ialah untuk mengetahui pengaruh ukuran perusahaan terhadap audit delay dengan return on asset sebagai variable mediasi pada sub sektor perbankan tahun 2017-2018. Penelitian ini menggunakan analisis descriptive dengan menggunakan aplikasi SPSS. Adapun sampel diambil dari 15 perusahaan sub sektor perbankan yang terdaftar di BEI pada tahun 2017-2018. Penelitian memanfaatkan Ukuran Perusahaan sebagai variable independen, Audit Delay sebagai variabel dependen serta Return On Asset sebagai variabel mediasi. Penelitian ini menggunakan analisis statistic data yaitu descriptive statistic , koefisien determinasi, signifikan test dan regresi analisis. Ukuran perusahaan dan audit delay berpengaruh signifikan pada perusahaan sector perbankan yang terdaftar di BEI pada tahun 2017-2018, diperkuat oleh Roa sebagai mediasi maka hasil signifikansi ukuran perusahaan terhadap audit delay semakin tinggi. Sedangkan untuk ROA juga memiliki hubungan signifikan dengan Audit Delay.
Tinjauan Yuridis Pengaturan Sanksi Pidana dalam Peraturan Daerah Provinsi Gorontalo
Authors: Nggilu Novendri Mohamad 
Published: September 2020

Politik hukum pembentukan Peraturan Daerah Provinsi Gorontalo sejak dibentuk tahun 2000, politik hukumnya masih bercita rasa pemidanaan, hal itu tercermin dari adanya pengaturan sanksi pidana yang bukan hanya melebihi dari ketentuan pembebanan sanksi pidana, melainkan juga kesalahan dalam merujuk ketentuan yang menentukan kualifikasi sebuah tindakan dibebankan sanksi pidana atau tidak. Tujuan penulisan ini adalah untuk menguraikan pengaturan sanksi pidana dalam Peraturan Daerah Provinsi Gorontalo. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian normatif dengan pendekatan statuta dan konseptual. Hasilnya ditemukan bahwa adanya peraturan daerah yang merujuk bukan pada pasal yang memuat tentang perbuatan hukum, melainkan merujuk pada BAB yang di dalamnya terdapat pasal-pasal yang umum dan tidak memuat perbuatan hukum yang dapat dikualifikasi sebagai perbuatan pidana, itu tercermin dari peraturan daerah tentang Pengelolaan Lingkungan Hidup. Di samping itu, terdapat juga peraturan daerah yang pembebanan sanksi pidananya melebihi dari ketentuan pengaturan sanksi yang dapat diatur dalam peraturan daerah, dimana pembebanan sanksi pidana kurungan 3 (tiga) tahun dan denda Rp. 500.000.000, padahal ketentuan dalam undang-undang tentang pembentukan peraturan perundang-undangan dan Permendagri tentang pembentukan produk hukum daerah hanya membatasi pembebanan sanksi pidana maksimal 6 (enam) bulan kurungan, dan denda paling banyak Rp. 50.000.000.
Short-term physical and chemical stability of mixtures of anti-tuberculosis drugs for intravenous administration
Authors: Кужко М.М. , Тлустова Т.М. , Денисов О.С. , Спринсян Т.А. , Шуха Ю.В. 
Published: September 2020

PURPOSE. To evaluate the stability of mixtures of anti-tuberculosis drugs for intravenous administration used for treatment of sensitive and resistant tuberculosis in time and in conditions close to the conditions of the use.
MATERIALS AND METHODS. Studied combinations: ethambutol + isoniazid in various concentrations, ethambutol + levofloxacin, ethambutol + moxifloxacin. In the stability study, samples were taken for analysis of the appearance, pH and concentration of drugs at specified times (immediately after mixing, after 16, and 24 hours).
RESULTS. The results of the chromatographic study indicate the absence of chemical interaction between the active pharmaceutical ingredients, high physical and chemical stability of the mixtures for up to 24 hours of storage under conditions close to the conditions of use, except the mixture of isoniazid with ethambutol, in which it is recommended to reduce the storage term to 16 hours due to the complexity of interpretation and the nature of potential impurities.
CONCLUSIONS. Study results indicate the possibility of simultaneous administration of a mixture of isoniazid and ethambutol when the preparation of the mixture was not more than 16 hours prior to administration and mixtures of ethambutol + levofloxacin and ethambutol + moxifloxacin with the preparation of the mixture no more than 24 hours before administration.
Pemanfaatan Tanaman Bakau Sebagai Bahan Ajar Untuk Meningkatkan Penguasaan Konsep Kimia Siswa SMP
Authors: Suyanti Suyanti 
Published: September 2020

Penelitian ini bertujuan untuk 1) Mengidentifikasi senyawa kimia dalam tanaman bakau (R.mangle) dengan teknik maserasi yang dapat dimanfaatkan untuk pemutih kulit 2) Mendiskripsikan bahan ajar “Bahan Kimia dalam kehidupan” untuk siswa kelas VIII yang terdapat dipasaran saat ini dilanjutkan dengan penyusunan bahan ajar sesuai kebutuhan siswa SMP kelas VIII 3) mendiskripsikan pengaruh penggunaan bahan ajar yang telah disusun terhadap prestasi belajar siswa kelas VIII pada materi Bahan Kimia dalam Kehidupan? Desain penelitian yang diterapkan adalah penelitian eksperimen. Penelitian dimulai dari pengambilan data laboratorium. Daun, batang dan akar bakau R.mangle diekstraksi maserasi untuk mendapatkan senyawa flavonoid, alkaloid dan triterpen dan steroid. Ekstrak R.mangle dibuat krim pemutih variasi konsentrasi 1%, 2%, dan 3%. Krim dari ekstrak R.mangle dicoba-ujikan pada kulit kelinci jantan yang berwarna hitam. Krim yang berasal dari daun R.mangle mencerahkan kulit kelinci dari hitam menjadi coklat tua. Krim dari kulit batang R.mangle mencerahkan kulit kelinci menjadi berwarna krem. Sedangkan krim dari akar membuat kulit kelinci berwarna coklat muda. Hasil data laboratorium dan uji-coba terhadap kulit kelinci, dimanfaatkan untuk menyusun bahan ajar “Bahan Kimia dalam Kehidupan”. Bahan ajar tersebut kemudian digunakan dalam pembelajaran pada siswa kelas VIII SMP N 38 Seluma. Hasil evaluasi belajar siswa memperlihatkan bahwa data hasil belajar siswa pada kelas eksperimen dan kelas kontrol memperlihatkan sebaran data yang normal dan menunjukkan varian data yang sama, sehingga data layak dianalisis menggunakan uji-t. Hasil uji t diperoleh t hitung 2,6011 dan t kritik dari tabel t adalah sebesar 1,9955 dikarenakan t hitung lebih besar dari t kritik maka ada perbedaan hasil belajar kelas eksperimen (Ye) dan kelas kontrol (Yk). Dengan demikian dapat disimpulkan bahwa prestasi belajar kelompok eksperimen yang menggunakan bahan ajar “Bahan Kimia dalam Kehidupan” pada pembelajaran IPA di kelas VIII A SMPN 38 Seluma memperoleh hasil lebih baik dari pada kelompok kontrol yang tidak menggunakan bahan ajar serupa dalam pembelajaran.
The difference an end-of-life diagnosis makes: qualitative interviews with providers of community health care for frail older people
Authors: Polak Louisa , Hopkins Sarah , Barclay Stephen , Hoare Sarah 
Published: September 2020

BackgroundIncreasing numbers of people die of the frailty and multimorbidity associated with old age, often without receiving an end-of-life diagnosis. Compared to those with a single life-limiting condition such as cancer, frail older people are less likely to access adequate community care. To address this inequality, guidance for professional providers of community health care encourages them to make end-of-life diagnoses more often in such people. These diagnoses centre on prognosis, making them difficult to establish given the inherent unpredictability of age-related decline. This difficulty makes it important to ask how care provision is affected by not having an end-of-life diagnosis.AimTo explore the role of an end-of-life diagnosis in shaping the provision of health care outside acute hospitals.Design and settingQualitative interviews with 19 healthcare providers from community-based settings, including nursing homes and out-of-hours services.MethodSemi-structured interviews (nine individual, three small group) were conducted. Data were analysed thematically and using constant comparison.ResultsIn the participants’ accounts, it was unusual and problematic to consider frail older people as candidates for end-of-life diagnosis. Participants talked of this diagnosis as being useful to them as care providers, helping them prioritise caring for people diagnosed as ‘end-of-life’ and enabling them to offer additional services. This prioritisation and additional help was identified as excluding people who die without an end-of-life diagnosis.ConclusionEnd-of-life diagnosis is a first-class ticket to community care; people who die without such a diagnosis are potentially disadvantaged as regards care provision. Recognising this inequity should help policymakers and practitioners to mitigate it.
URGENSI PSIKOLOGI DALAM AKTIVITAS DAKWAH
Authors: Fabriar Silvia Riskha 
Published: September 2020

Abstract

Da’wah is an Islamic communication, which is a communication activity carried out intentionally and consciously in the form of an invitation to the path of God with amar ma'ruf nahi munkar to achieve the happiness of humanity in the world and the hereafter. When preaching, the preacher needs to even have to know the psychological condition of the object being preached (mad'u) so that what is conveyed can later be conveyed properly. In this case, psychology provides a way to convey material and establish methods of preaching to humans who are totality (psychophysical) creatures and have personalities from both internal and external influences. Thus, psychology in the process of da'wah has a focal point in the knowledge of human behavior. Based on psychiatric or psychological elements, the process of preaching will proceed according to the needs that are expected of humans as individuals and social beings.
Keywords: da’wah, communication, psychology condition

Dakwah merupakan suatu komunikasi Islam, yaitu suatu aktivitas komunikasi yang dilakukan secara sengaja dan sadar yang berupa ajakan kepada jalan Allah dengan amar ma’ruf nahi munkar untuk meraih kebahagiaan manusia dunia dan akhirat. Ketika berdakwah, da’i perlu bahkan harus mengetahui kondisi psikologis objek yang didakwahi (mad’u) agar apa yang disampaikan nantinya dapat tersampaikan dengan baik. Dalam hal ini, psikologi memberikan jalan bagaimana menyampaikan materi dan menetapkan metode dakwah kepada manusia yang merupakan makhluk totalitas (psikofisik) dan memiliki kepribadian baik dari faktor dalam maupun pengaruh dari luar. Dengan demikian, psikologi dalam proses dakwah mempunyai titik perhatian pada pengetahuan tentang tingkah laku manusia. Dengan berlandaskan unsur-unsur kejiwaan atau psikologi, proses dakwah akan berjalan sesuai kebutuhan yang diharapkan manusia sebagai individu dan makhluk sosial.
Kata kunci: dakwah, komunikasi, kondisi psikologis
Cognitive Function and Uremic Toxins after Kidney Transplantation: An Exploratory Study
Authors: te Linde Elsemieke , van Roij Claudette J.M. , Meijers Bjӧrn K.I. , De Loor Henriette , Kessels Roy P.C. , Wetzels Jack F.M. 
Published: September 2020

Background
Cognitive functions are altered in patients with CKD. However, it is suggested that cognitive functions improve after kidney transplantation, at least partially. A possible cause for this improvement could be the reduction of uremic retention solutes after transplantation. This study assessed the association between the changes in uremic toxin concentration with the changes in cognitive function in patients after kidney transplantation.

Methods
Ten recipients of kidney transplants were compared with 18 controls (nine patients on hemodialysis, and nine patients with CKD stage 4 or 5 [eGFR <30 ml/min per 1.73 m2] who were not on dialysis). An extensive neuropsychological assessment, covering the five major cognitive domains (i.e., memory, attention and concentration, information processing speed, abstract reasoning, and executive function), was done before transplantation, at 1 week post-transplant, and 3 months after transplantation. Similarly, assessments of the 18 matched, control patients were performed longitudinally over a period of 3–5 months. Concentrations of 16 uremic retention solutes (indoxyl glucuronide, p-cresyl glucuronide, phenylglucuronide, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid, indoxyl sulfate, p-cresyl sulfate, hippuric acid, phenyl sulfate, kynurenine, tryptophan, kynurenic acid, tyrosine, indole-3-acetic acid, phenylalanine, trimethylamine N-oxide, and phenylacetylglutamine) were measured in serum samples collected at the time of the neuropsychological assessments.

Results
A significant improvement in cognitive function was only found in the processing-speed domain, and this was observed in both patients who received a transplant and patients with CKD. No significant differences between patients who received a transplant and the control groups were seen in the other cognitive domains. As expected, the serum concentration of most uremic toxins decreased significantly within 1 week after kidney transplantation.

Conclusions
There was no significant improvement in cognitive function that could be specifically related to kidney transplantation in the first 3 months after the procedure. These data do not support the notion that uremic toxins exert an immediate effect on cognitive function.
Benign Vokal Kord Hastalıklarında Tedavi Etkinliğinin Ses Analizi ile Değerlendirilmesi
Authors: ÜLKÜMEN Burak , ESKİİZMİR Görkem , ÇELİK Onur , DOMBAYCI Onur 
Published: September 2020

Amaç: Benign vokal kord patolojilerinde ses terapisi ve fonocerrahinin etkinliğini belirlemek.
Materyal Metot: Manisa Celal Bayar Üniversitesi KBB polikliniğine Eylül 2015-Mayıs 2019 tarihleri arasında ses kısıklığı ile başvuran ve akustik ses analizi yapılan 79 (35 K, 44 E) hasta çalışmaya dahil edilmiştir. Ses analizinde hastanın başvuru sırasında ve tedavi sonrası 3. ayda auidio-technica AT2005USB marka mikrofon ile alınan kayıtları karşılaştırılmıştır. Akustik analiz çok boyutlu ses analiz programı (Multi-Dimensional Voice Program- MDVP) kullanılarak yapılmıştır. F0, vF0, Jitter, Shimmer, APQ, NHR ve VTI parametreleri analiz edilmiştir. Ses kayıtları alınmıştır. Ses analizi değerleri gurup bazında tedavi öncesi ve sonrası “eşli örneklem t testi” kullanılarak karşılaştırılmıştır. Veriler ortalama ± standart sapma (SD) olarak sunulmuştur. Güven aralığı 95% ve p
O “Narciso”, de Luís de Montalvor, e a paisagem em delírio
Authors: Gebra Fernando De Moraes 
Published: September 2020

O presente artigo desconstrói uma imagem cristalizada na historiografia literária luso-brasileira de que a revista Orpheu é o órgão do Modernismo Português. A leitura atenta de todos os poemas e fragmentos de prosa estampados nessa revista literária permite concluir que, tal como afirma Fernando Pessoa em carta a Camilo Pessanha, Orpheu apresenta “poemas e prosas que vão do ultra-simbolismo até ao futurismo”. Toda a apresentação centra-se no poeta e diretor do primeiro número de Orpheu, Luís de Montalvor (1891-1947). Abordo, rapidamente, algumas metáforas de leitura feitas sobre a obra de Montalvor, para, em seguida, concentrar-me no estudo analítico do poema “Narciso” (publicado no segundo número de Orpheu), destacando as metamorfoses do mito clássico de Narciso, a paisagem em delírio, os espectros do duplo, a linguagem multifacetada e os efeitos de sentido gerados pelas escolhas lexicais. Durante o processo analítico do poema, discuto os procedimentos estéticos do autor, imbricados na tradição do Decadentismo-Simbolismo, relacionando-os com os textos doutrinários (“Introdução” de Orpheu 1 e “Tentativa de um ensaio sobre a Decadência”, da revista Centauro).
Frequency of coexistence and kinetics of the BCR-ABL1 transcript level and allele burden of JAK2V617F and CALR Type 1, 2 gene mutations in patients with chronic myeloid leukemia
Authors: Abdullaev A. O. , Stepanova E. A. , Makarik T. V. , Nikulina E. Y. , Treglazova S. A. , Goryacheva S. R. , Shukhov O. A. , Bykova A. V. , Tratsevskaya Z. V. , Melikyan A. L. , Kovrigina A. M. , Turkina A. G. , Sudarikov A. B. 
Published: September 2020

Introduction. The pathogenesis of myeloproliferative neoplasms is associated with the chimeric gene BCR-ABL1 or with one of the driver mutations in the genes JAK2, MPL and CALR (Calreticulin). However, the classifi cation of the World Health Organization lists no myeloid neoplasms with more than one driver genetic abnormality. Aim. To search for mutations in the genes JAK2, MPL and CALR in patients with BCR-ABL1-positive chronic myeloid leukemia (CML), as well as to evaluate the kinetics of the discovered mutations during tyrosine kinase inhibitor (TKI) therapy. Materials and methods. mRNA and DNA samples isolated from blood and bone marrow cells of 567 CML patients, who underwent periodic monitoring of the BCR-ABL1 transcript level over the 2012–2019 period were included in the study The BCR-ABL1 transcript level was determined using a highly sensitive quantitative real-time polymerase chain reaction. The mutations JAK2V617F and MPLW515L/K were detected using real-time quantitative allele-specifi c polymerase chain reaction. Mutations in the CALR gene were investigated using fragment analysis followed by Sanger sequencing. Results. The combination of the BCR-ABL1, JAK2 and CALR gene mutations among CML patients receiving TKIs was 1.23 % (7/567). Out of these, the combination of BCR-ABL1 with JAK2V617F and the combination of BCR-ABL1 with CALR gene mutations were detected in 0.88 % (5/567) and 0.35 % (2/567) of cases, respectively. During TKI therapy, in 5 out of 7 patients, the level of BCR-ABL1 reached major molecular response (MR). In 4 of these patients, the therapy was discontinued. These patients are currently in molecular remission. In the remaining 2 patients, major MR was not achieved, despite the use of second-generation TKI preparations. Conclusions. The combination of the BCR-ABL1 chimeric gene with gene mutations Jak2 or CALR was a rare event and amounted to 0.88 and 0.35 % of cases, respectively. The combination of BCR-ABL1 with Jak2V617F and CALR mutations does not always impede the achievement of major MR.
Evaluation of the effi ciency of the activity of the register of potential donors of hematopoietic stem cells
Authors: Loginova M. A. , Malysheva N. A. , Minaeva N. V. , Paramonov I. V. 
Published: September 2020

Introduction. One of the problems in providing Russian transplant clinics with unrelated hematopoietic steam cells (HSCs) is the lack of an interaction scheme “Registry — HSC collection center — Transplant center”. In order to ensure effective operation at the donor activation stage, registries need regulated and stable cooperation with the Collection center with a clear distribution of duties and responsibilities for both parties. Aim: to evaluate the effectiveness of the Kirov Registry.Materials and methods. Since 2009, the Kirov Registry has been systematically working with HSC donors (as of 25/11/2019, the total number of donors was 46,922, of which 43 % male, 57 % female; 49 % regular blood donors, 51 % volunteers from donor actions) since 2013. The Registry has its own Collection Center. The effectiveness of the Registry was evaluated by indicators: the number of donations, donor activation time, the number of refusals at the stages of preliminary activation and donation of cellular material. Results. As of 25/11/2019, more than 1,000 preliminary activations of potential HSC donors were performed, of which 175 were completed by collection of HSCs. The use of the created and validated activation model with the employment of the Registry and the Collection Center currently provides the following activation times: the period for sending a sample for confi rming HLA typing does not exceed 14 days; the total time to satisfy the transplant center request for cellular material does not exceed 2 months. A detailed analysis of the causes of refusals at the stages of preliminary activation and after receiving a request for the collection of cell material was carried out. Conclusion. Between 2009 and 2019 the Kirov registry has developed a model of effective work with the donors of the HSCs at all stages of the chain “Registry — HSC collection center — Transplant center”. The effectiveness of the work is confi rmed by the demand for donors, observance of the donor activation time, and a relatively low percentage of refusals from donations.