bluuebunny/crossref_metadata_2025_split huggingface dataset:
Randomized, Controlled Trial of Tacrolimus and Prednisolone Monotherapy for Adults with De Novo Minimal Change Disease
Authors: Medjeral-Thomas Nicholas Rhys , Lawrence Christopher , Condon Marie , Sood Bhrigu , Warwicker Paul , Brown Heather , Pattison James , Bhandari Sunil , Barratt Jonathan , Turner Neil , Cook H. Terence , Levy Jeremy B. , Lightstone Liz , Pusey Charles , Galliford Jack , Cairns Thomas D. , Griffith Megan 
Published: January 2020

Background and objectives
Minimal change disease is an important cause of nephrotic syndrome in adults. Corticosteroids are first-line therapy for minimal change disease, but a prolonged course of treatment is often required and relapse rates are high. Patients with minimal change disease are therefore often exposed to high cumulative corticosteroid doses and are at risk of associated adverse effects. This study investigated whether tacrolimus monotherapy without corticosteroids would be effective for the treatment of de novo minimal change disease.

Design, setting, participants, & measurements
This was a multicenter, prospective, open-label, randomized, controlled trial involving six nephrology units across the United Kingdom. Adult patients with first presentation of minimal change disease and nephrotic syndrome were randomized to treatment with either oral tacrolimus at 0.05 mg/kg twice daily, or prednisolone at 1 mg/kg daily up to 60 mg daily. The primary outcome was complete remission of nephrotic syndrome after 8 weeks of therapy. Secondary outcomes included remission of nephrotic syndrome at 16 and 26 weeks, rates of relapse of nephrotic syndrome, and changes from baseline kidney function.

Results
There were no significant differences between the tacrolimus and prednisolone treatment cohorts in the proportion of patients in complete remission at 8 weeks (21 out of 25 [84%] for prednisolone and 17 out of 25 [68%] for tacrolimus cohorts; P=0.32; difference in remission rates was 16%; 95% confidence interval [95% CI], −11% to 40%), 16 weeks (23 out of 25 [92%] for prednisolone and 19 out of 25 [76%] for tacrolimus cohorts; P=0.25; difference in remission rates was 16%; 95% CI, −8% to 38%), or 26 weeks (23 out of 25 [92%] for prednisolone and 22 out of 25 [88%] for tacrolimus cohorts; P=0.99; difference in remission rates was 4%; 95% CI, −17% to 25%). There was no significant difference in relapse rates (17 out of 23 [74%] for prednisolone and 16 out of 22 [73%] for tacrolimus cohorts) for patients in each group who achieved complete remission (P=0.99) or in the time from complete remission to relapse.

Conclusions
Tacrolimus monotherapy can be effective alternative treatment for patients wishing to avoid steroid therapy for minimal change disease.

Podcast
This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2020_01_16_CJN06180519.mp3
Overview of Motivation for Elderly Services for Control and Satisfaction in Polyclinic RSST Klaten
Authors: Azzaky Azzaky , Arief Amrizal 
Published: January 2020

<em>Background: Elderly during the examination were hoping to get good health care. Elderly will be motivated to check when he is satisfied with the services provided by health workers in hospitals. The purpose of this study was to Study the picture of the elderly to check the level of motivation and satisfaction in the service of RSST Klaten Policlinic. The design used in this study is Despriptif. The population is all the elderly who checked up in RSST Klaten. Samples are 96 respondents and taken with consecutive sampling technique. The variable in this study was to examine elderly motivation and service satisfaction. Data were collected with a structured interview, then processed based on the frequency distribution. Methods: The design of this study is descriptive. This study was conducted On September 1 - 30, 2019. Variable in this research is Elderly Motivation For Control and Service Satisfaction. In this research The population is all elderly ones Control at RSST Klaten Polyclinic Based on data from Medical Record Hospital SOERADJI TIRTONEGORO during the month August 2019 number of elderly patients who Control at RSST Klaten Polyclinic As many as 598 patients. Result The results of the study of 96 The respondent got none Respondents who have a level Less motivation, motivation level Quite as much as 2 respondents (2%) And high level of motivation as much 94 respondents (98%). Conclusions : Level of elderly motivation for Control at Polyclinic RSST Klaten majority is high As many as 94 respondents (98%). This matter Caused by age, type Sex and education of respondents and Satisfaction of the ministry Received patients at Polyclinic RSST Klaten.</em>
Documentation of Indigenous Knowledge on Folk Medicine in Doddakavalande Doddakavalande Hobli, Nanjangud Taluk of Mysore District, Karnataka
Authors: Nagalakshmi M , Rashmi S 
Published: January 2020

An ethnobotanical survey was conducted to collect information from traditional healers on the use of herbal medicine in Doddakavalande Hobli, Nanjangud taluk of Mysore District. The indigenous knowledge of local healers was documented through questionnaire and personal interviews. In the present study, about 19 respondents of age group between 50 to 89 yrs gave information of traditional medicines used to cure different ailments. Of about 35 plant species belonging to 26 families were used for the treatment of human ailments. In which family Fabaceae and Polygonaceae contained 3 plant species, followed by Acanthaceae, Amaranthaceae, Apocynaceae, Cucurbitaceae, Poaceae contained 2 species each, and the rest of the families Amaryllidaceae, Anacardiaceae, Apiaceae, Aristolochiaceae, Asteraceae, Cleastraceae, Crassulaceae, Lamiaceae, Lecythidaceae, Meliaceae, Olaceae, Phylanthaceae, Piperaceae, Plumbaginaceae, Poaceae, Polygonaceae, Rutaceae, Smilacaceae, Solanaceae, Styracaceae and Zingiberaceae. Habit wise analysis of medicinal plant species used indicated that herbs (19 species) were the most preferred life form followed by trees (8 species), shrubs (5 species) and climbers (3 species) for drug formulation. Herbal formulations were administrated either internally or applied externally depending on the type of ailment. Local people in the study area possess traditional knowledge of medicinal plants to treat various human ailments, therefore it is necessary to preserve the indigenous knowledge on traditional medicines by proper documentation, identification of plant species used, and herbal preparation.
Keywords: Ethnobotany, Traditional knowledge, Medicinal plants, Mysore district.
The Burden of Atrial Fibrillation as Stroke Risk Factor in Southeast Asia: A Systematic Review
Authors: Pinzon Rizaldy Taslim , Karunawan Niyata Hananta 
Published: January 2020

Introduction Stroke is the most burden complication in a patient with atrial fibrillation. Atrial Fibrillation (AF) is the common cardiac arrythmia in stroke patients. The epidemiology study of AF-associated stroke were limited published research in southeast. This study may prove valuable in routine clinical practice. This systematic review aimed to identify the latest evidence on the epidemiology of AF related stroke in southeast Asia regions.
Methods: We performed a comprehensive search on prevalence or incidence of atrial fibrillation related stroke from inception up until September 2019 through PubMed and Cochrane Central Database. The keywords were the combination of the following words: “stroke”, “epidemiology”, “atrial fibrillation”, and was then used with the name of each country in southeast Asia”. The inclusion criteria of the study i.e : patients with stroke, was a original papers with observational study, concerned on AF in stroke patients in southeast Asia. Data on incidence and prevalence were obtained from hospital-based studies and community-based studies.
Results: Atrial Fibrillation prevalence data are available in five countries in southeast Asia, a total of the 11 articles identified were from Malaysia, Thailand, Vietnam, Singapore, and Indonesia were also represented. The reported prevalence of AF as a risk factor of stroke patients was 2.6 % until 23.04% based on hospital-based studies.
Conclusion: AF is one of risk factors that associated with the stroke. This study also showed that prevalence AF in South East Asia ranged 2.6 – 23.04 % . However, owing to the limited number of studies in southeast Asian countries, further investigation is needed before drawing a definite true of prevalence of AF in the southeast Asia population.
Keywords: Atrial Fibrillation, AF-associated Stroke, Epidemiology, Risk Factors.
Ligand Decorated Embelin Loaded PLGA Nanoparticles for Management of Alcohol Induced Hepatotoxicity
Authors: Kumar Ajay , Khan M. Nikhat , Kanoujia Jovita , Singh Amandeep , Mishra Neeraj 
Published: January 2020

Preparation of surface modified Embelin loaded nanoparticles (GA-PEG-PLGA) for the management of hepatotoxicity. Surface modified Embelin loaded GA-PEG-PLGA NPs were evaluated by NMR, FTIR, TEM techniques and in vitro release studies. The biodistribution of the nanoparticles was assessed by High-performance liquid chromatography (HPLC), and the cellular uptake study was evaluated using Hep G2 cells (liver cells lines). The hepatoprotecttive effect of the surface modified Embelin loaded GA-PEG-PLGA NPs was investigated in-vitro and in-vivo. The surface modified Embelin loaded GA-PEG-PLGA nanoparticles significantly increases the uptake of drug in liver by 2.5 folds more than plain drug.
Keywords: Glycyrrhetinic acid, Receptor mediated, Surface functionalization, Embelin, PLGA nanoparticle.
Analytical method development and validation for the determination of Brinzolamide by RP-HPLC
Authors: Tiwari Balakrishna , Shirsat Mrunal K. , Kulkarni Amol 
Published: January 2020

Brinzolamide is inhibitor of carbonic anhydride and is highly specific and non-competitive. The aim of the present study is to develop a simple, precise, accurate, sensitive RP-HPLC method for the determination of bulk drug. The objective of the method validation is to demonstrate whether the method was suited for the intended purpose. The method was validated as per the ICH guidelines. The method was validated for linearity, precision (repeatability, intermediate precision), accuracy, specificity, robustness, ruggedness, limit of detection and limit of quantification. Cosmosil (4.6X250mm, 5 μ) column was used for separation. The selected wavelength for Brinzolamide was 254 nm. The mobile phase consists of Acetonitrile: Potassium dihydrogen phosphate buffer (40:60). Flow rate was delivered at 1.0 mL/min. Appropriate dilutions of standard stock solutions were prepared to get desired concentrations in the range of 100-500 mcg/ml. The equation od standard curve was y = 441.8x + 1132 and R2 = 0.998. The RT obtained was 6.6167 minutes.
Keywords: Brinzolamide, UV spectroscopy, RP-HPLC, ICH
Psychotic Disorders, Definition, Sign and Symptoms, Antipsychotic Drugs, Mechanism of Action, Pharmacokinetics & Pharmacodynamics with Side Effects & Adverse Drug Reactions: Updated Systematic Review Article
Authors: Bangwal Rohit , Bisht Shivam , Saklani Saurabh , Garg Shobit , Dhayani Mohan 
Published: January 2020

Psychosis is a mental disorder characterized by a disconnection from reality. Psychosis is a group of disorder characterized by thought disorder, abnormal behaviour, defective cognition, delusion and hallucination. Adverse drug reaction is defined as any undesired or unintended effects of drugs treatment. According to the World Health Organization (WHO)- “adverse drug reaction (ADRs) has been defined one which is noxious and unintended, and which occurs at doses normally used in man for prophylaxis, diagnosis, or therapy of disease, or modification of physiological function”. Adverse drug reactions are the most important causes of the mortality and morbidity. Antipsychotics are the most effective drugs which are used in the psychiatry in the maintenance therapy of mania, psychoses and schizophrenia. The antipsychotics drugs are chemically disparate but have the common property of alleviating the symptoms of organic as well as functional psychosis. But they also have a capacity to cause a wide range of potential adverse drug reactions that can lead to non-compliance that can impair quality of life, may cause the extra pyramidal symptoms which can lead to discontinuation of therapy and in extreme cases it may be fatal. Knowledge of assessment of ADRs due to different antipsychotics is necessary. It helps to choose to safe treatment and reduce the risk of occurrence of ADRs by the clinicians. ADR are often poorly identified and reported in day to day medical practice. As we collect more and more information about ADRs, we need an active surveillance system regarding identification and reporting of ADRs with antipsychotic drugs. On many review articles are read & ward round participation experiences we find that antipsychotic drugs can have shown a various kind of ADRs. Psychiatrist and clinical pharmacist are need to be made aware of these potentially fatal adverse effects associated with antipsychotic drugs via conduction of patients counseling regarding (drugs, disease, doses & side effects), quality-based seminars, published medical literature, conferences, learning programs and health care camps.
Keywords: Antipsychotic Drugs, WHO, Adverse Drug Reactions, Pharmacovigilance, Psychiatrist.
PEMBUATAN KONSENTRAT PROTEIN DARI BIJI KELOR (Moringa oleifera L.) DAN ANALISIS PROFIL ASAM AMINO
Authors: Nurhayati Nurhayati , Mappiratu Mappiratu , Musafira Musafira 
Published: January 2020

Penelitian tentang pembuatan konsentrat protein dari biji kelor dan analisis profil asam amino telah dilakukan, dengan tujuan untuk menentukan tingkat kejenuhan amonium sulfat yang menghasilkan konsentrat protein dengan rendemen dan kadar protein tertinggi, rasio tepung biji kelor terhadap amonium sulfat yang menghasilkan konsentrat protein dengan rendemen dan kadar protein tertinggi, dan mengetahui profil asam amino konsentrat protein biji kelor. Penelitian ini dilakukan dengan menggunakan rancangan acak lengkap (RAL), dengan variasi tingkat kejenuhan amonium sulfat 50%, 60%, 65%, 70%, 75%, 80% dan variasi rasio tepung biji kelor terhadap amonium sulfat 1:2, 1:3, 1:4, 1:5, dan 1:6 (b/v), setiap perlakuan dilakukan sebanyak 2 kali. Tingkat kejenuhan amonium sulfat terbaik diperoleh pada 65% dengan rendemen sebesar 46,56% dan kadar protein 72,18%. Rasio amonium sulfat terhadap tepung biji kelor diperoleh rasio terbaik 1:6 dengan rendemen sebesar 70,96% dan kadar protein sebesar 74,16%. Profil asam amino konsnentrat protein biji kelor yaitu asam amino essensial berupa arginin (77,3 mg/g), fenilalanin (27,61 mg/g), leusin (27,39 mg/g), valin (15,19 mg/g), isoleusin (13,16 mg/g), threonin (11,29 mg/g), metionin (10,67 mg/g), lisin (7,57 mg/g), dan triptofan (3,49 mg/g). Asam amino non essensial berupa asam glutamat (97,2 mg/g), prolin (26,3 mg/g), glisin (24,74 mg/g), alanin (17,57 mg/g), asam aspartat (17,45 mg/g), serina (15,16 mg/g), tirosin (11,29 mg/g), dan sistina (5,9 mg/g).Kata kunci : Asam amino essensial biji kelor, Biji kelor, Konsentrat protein, Profil asam amino
EKSTRAKSI DAN KARAKTERISASI PEKTIN DARI KULIT BUAH KLUWIH (Artocarpus camansi Blanco)
Authors: Febriyanti Yesy , Razak Abd. Rahman , Sumarni Ni Ketut 
Published: January 2020

Telah dilakukan penelitian tentang ekstraksi dan karakterisasi pektin dari kulit buah kluwih (Artocarpus camansi Blanco). Penelitian ini bertujuan untuk mengetahui rasio dan waktu terbaik yang diperlukan untuk menghasilkan ekstrak pektin dengan rendemen tertinggi. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri atas 2 faktor yaitu rasio perbandingan sampel terhadap pelarut dan waktu ekstraksi yang masing–masing dilakukan sebanyak 3 kali. Hasil penelitian menunjukan bahwa rasio terbaik diperoleh pada perbandingan 1:50 b/v dengan rendemen pektin 47,2% dan waktu terbaik diperoleh pada 120 menit dengan rendemen 48,30%. Hasil karakterisasi pektin yang diperoleh antara lain yaitu kadar air 1,55%, kadar abu 2,2 %, berat ekivalen 609,99 mg, metoksil 11,49%, kadar galakturonat 42,47%, derajat esterifikasi 47,65% dan berat molekul 16.177,83 g/mol.Kata Kunci : ekstraksi, karakterisasi, pektin, kluwih.
STUDI REAKSI SENYAWA SITRONELAL DENGAN L-TIROSINA DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus aureus
Authors: Rusdin Famri , Ys. Hardi , Syamsuddin Syamsuddin 
Published: January 2020

Penelitian modifikasi dan sintesis senyawa kimia untuk tujuan antibakteri terus berkembang, diantaranya adalah kajian hubungan antara struktur senyawa dengan aktivitas antibakteri. Penelitian ini dilakukan melalui kajian reaksi dua senyawa yaitu sitronelal dan L-tirosinaa yang ada hubungannya antara struktur senyawa dan aktivitas antibakteri terhadap Staphylococcus aureus. Reaksi tersebut menggunakan metode schiff base dengan cara merefluks campuran dengan katalis KOH pada suhu 600C selama 8 jam. Hasil reaksi dikarakterisasi dengan KLT dan Spekrofotometri IR. Senyawa hasil sintesis berbentuk padatan amorf berwarna kuning dengan berat 0,061 gram beserta titik leleh 265-269oC. Hasil pengujian antibakteri terhadap Staphylococcus aureus menggunakan metode dilusi pada konsentrasi 1200 µg/mL. Sifat antibakteri hasil reaksi mengindikasikan masih adanya hubungan struktur senyawa dengan aktivitas yang lemah.Kata kunci : Sitronelal, L-tirosina, Aktivitas antibakteri, Staphylococcus aureus.
PENGARUH PENAMBAHAN AKTIVATOR DALAM PEMBUATAN KARBON AKTIF AMPAS TAHU SEBAGAI ADSORBEN MINYAK JELANTAH
Authors: Ma'rifah Ma'rifah , Jamaluddin Jamaluddin , Yuyun Yonelian , Widodo Agustinus 
Published: January 2020

Minyak goreng yang telah digunakan berulang kali akan mengalami kerusakan seperti peningkatan bilangan peroksida dan asam lemak bebas yang dapat menimbulkan bahaya bagi kesehatan. Penelitian ini memvariasikan aktivator pada proses pembuatan karbon aktif ampas tahu yaitu NaCl 10%, Na2CO3 5% dan H3PO4 1M untuk mengetahui pengaruhnya terhadap kadar asam lemak bebas dan bilangan peroksida dalam minyak jelantah. Minyak yang digunakan adalah minyak goreng kemasan yang digunakan untuk menggoreng ikan kering, ikan basah, tahu-tempe dan daging ayam. Tahapan pemurnian minyak yaitu proses despising, netralisasi dan bleaching. Pengujian mengacu pada SNI (Standar Nasional Indonesia) 7709:2012 sebagai syarat mutu minyak goreng. Hasil penelitian menunjukkan kadar asam lemak bebas tertinggi dan terendah yang diperoleh yaitu 0,1925% dan 0,1473%, sedangkan bilangan peroksida tertinggi dan terendah yaitu 9,3203 meq O2/kg dan 4,3526 meq O2/kg. Aktivator yang paling berpengaruh pada penurunan kadar asam lemak bebas dan bilangan peroksida adalah Na2CO3 dimana diperoleh kadar rata – rata asam lemak bebas 0,1473% dengan persentase penurunan sebesar 57,68% dan kadar rata – rata penurunan bilangan peroksida yaitu 4,3526 meq O2/kg dengan persentase penurunan sebesar 59,04%. Jadi, aktivator Na2CO3 merupakan aktivator yang paling baik digunakan untuk aktivasi karbon ampas tahu sebagai adsorben minyak jelantah.Kata Kunci: Aktivator, Karbon Aktif, Ampas Tahu, Adsorben, Minyak Jelantah.
KARAKTERISASI PIGMEN HASIL EKSTRAKSI AIR-ETANOL DARI BUAH SENGGANI (Melastoma malabathricum)
Authors: Ondagau Debi Christa , Ridhay Ahmad , Nurakhirawati Nurakhirawati 
Published: January 2020

Telah dilakukan penelitian tentang Karakterisasi Pigmen Hasil Ekstraksi Air-Etanol Dari Buah Senggani (Melastoma malabathricum). Penelitian ini diawali dengan melakukan ekstraksi buah senggani secara maserasi menggunakan enam perbandingan kombinasi volume pelarut air:etanol yaitu 0:100; 5:95; 10:90; 15:85; 20:80 dan 25:75. Rendemen terbaik dari ekstraksi buah senggani didapatkan dari perbandingan pelarut 0:100 yaitu 4,7 %. Kemudian Ekstrak dianalisis dengan spektrofotometer UV-Vis, FTIR dan uji golongan senyawa. Spektrum UV-Vis ekstrak buah senggani dihasilkan pada panjang gelombang 540 nm dan interpretasi FTIR menunjukkan bahwa ekstrak mengandung gugus fungsi seperti O-H alkohol, C-O-C eter, C=C aromatik, C-H aromatik. Hasil uji golongan menunjukkan ekstrak mengandung senyawa flavonoid jenis antosianin.Kata kunci : Buah senggani, ekstraksi, antosianin
STUDI PERBANDINGAN RENDEMEN PRODUKSI XANTOFIL DAN KAROTEN KAPANG ONCOM MERAH PADA BERBAGAI WAKTU INKUBASI
Authors: Asniawati Asniawati , Ridhay Ahmad , Prismawiryanti Prismawiryanti 
Published: January 2020

Telah dilakukan penelitian tentang studi perbandingan rendemen produksi xantofil dengan karoten kapang oncom merah pada berbagai waktu inkubasi. Penelitian ini bertujuan untuk mengetahui jumlah rendemen fraksi kelompok xantofil dan karoten dari berbagai waktu inkubasi kapang oncom merah pada medium tongkol jagung. Pengujian dilakukan dengan mengukur absorbansi ekstrak xantofil dan karoten pada instrumen spektrofotometer uv vis, parameter yang diamati adalah waktu inkubasi spora kapang oncom merah. Waktu inkubasi yang digunakan adalah dimulai dari hari ke 2, 3, 4, 5, 6, dan ke 7. Hasil penelitian menujukkan bahwa waktu inkubasi yang menghasilkan jumlah rendemen xantofil efektif pada hari ke 3 dengan rerata rendemen sebesar 4,435%. Sedangkan jumlah rendemen karoten efektif pada hari ke 5 dengan rerata rendemen 4,532%.Kata kunci: Xantofil, karoten, kapang oncom merah, waktu inkubasi, rendemen
KADAR PROTEIN TERLARUT DAN GULA TOTAL BISKUIT FUNGSIONAL BERAS JAGUNG (Zea mays l) FERMENTASI
Authors: Mandjoro Stevi Evalin , Nurhaeni Nurhaeni , Indriani Indriani , Jusman Jusman 
Published: January 2020

Telah dilakukan penelitian tentang kadar protein terlarut dan gula total biskuit fugsional beras jagung fermentasi. Penelitian ini bertujuan untuk mengetahui waktu fermentasi yang memiliki kadar protein terlarut dan gula total tertinggi terhadap biskuit fungsional. Variasi waktu fermentasi untuk menentukan kadar protein terlarut dan gula total biskuit fungsional yaitu (12, 24, 36, 48 dan 60 jam). Diperoleh hasil analisis perlakuan yang terbaik terhadap biskuit fungsional adalah pada waktu fermentasi selama 60 jam dengan kadar protein terlarut 2,274% dan kadar gula total 15,114%. Sedangkan hasil analisis untuk uji organoleptik biskuit fungsional yaitu nilai kesukaan rasa tertinggi diperoleh pada waktu fermentasi selama 60 jam yaitu 5,4 (suka).Kata Kunci: beras jagung, fermentasi, biskuit, protein terlarut, gula total
EKSTRAKSI PEKTIN PADA KULIT BUAH KLUWIH (Artocarpus camansi Blanko) PADA BERBAGAI SUHU DAN KONSENTRASI ASAM SITRAT
Authors: Demsi Reski Putriani , Ruslan Ruslan , Rahim Erwin Abdul , Ys Hardi 
Published: January 2020

Telah dilakukan penelitian tentang ekstraksi pektin pada kulit buah kluwih (Artocarpus camansi Blanko) pada berbagai suhu dan konsentrasi asam sitrat. Penelitian ini bertujuan untuk mengetahui konsentrasi dan suhu ekstraksi yang menghasilkan pektin dari kulit buah kluwih (Artocarpus camasni Blanko) dengan rendemen tinggi. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan empat variasi suhu (90 oC, 100 oC, 110 oC dan 120 oC) dan empat variasi konsentrasi (5%, 7%, 9%, dan 11%), dengan menggunakan metode ekstraksi meserasi. Hasil penelitian ini menunjukan rendeman tertinggi didapatkan pada konsentrasi 9% sebesar 35,65% dan suhu 90 oC sebesar 40,69%. karakteristik terhadap pektin adalah kadar metoksil 8,12 %, kadar galakturonat 41,88 %.Kata Kunci : Ekstraksi pektin, kadar metoksil, kadar galakturonat
BIOSORBEN KITOSAN CANGKANG KEONG SAWAH TERHADAP PENYERAPAN ZAT WARNA METHYLENE BLUE
Authors: Rais Iget , Nurhaeni  , Ruslan  , Pusptasari Dwi Juli 
Published: January 2020

Biosorbent studies on methylene blue absorption using chitosan from rice conch shell have been carried out. This research was carried out with variations in contact time of 1, 2, 3, 4, 5, and 6 hours with the aim to determine the contact time required to adsorb Methylene Blue dyes by chitosan from rice conch shell with the highest adsorption capacity. The results showed that the contact time required to adsorb Methylene Blue dye by a chitosan from rice conch shell was 6 hours with the highest adsorption capacity of 85.05%.
Keywords: Chitosan, adsorption, Methylene Blue