bluuebunny/crossref_metadata_2025_split huggingface dataset:
Control of Amazonian Leaf-Cutting Ants (Hymenoptera: Formicidae): A Multi-criteria Analysis
Authors: Dionisi Mathilde , Ozier-Lafontaine Harry , Laplace Damien 
Published: December 2020

AbstractLeaf-cutting ants (Hymenoptera: Formicidae) are one of the main pests found in the Americas and they cause global economic losses worth several billions of dollars. While pesticides have been the most widely used control method, new management alternatives in a context of agroecological transition are now being considered. This study focuses on the leaf-cutting ants species found in the pan-Amazon region. As part of efforts to improve management of these pests, this multi-criteria analysis of control strategies covers a total of 691 experiments collected from 153 studies, and the control were evaluated as a function of their management efficacy, environmental and human health impacts, and their ease of application. Chemical control methods were effective but posed a danger to human health and the environment, whereas mechanical methods and integrated management were more sustainable but not always very effective. Some of the biocontrol methods were evaluated as effective and safe for the environment and human health, including the use of entomopathogenic fungi Beauveria bassiana (Bals.-Criv) Vuill. (Hypocreales: Cordycipitaceae) and Metarhizium anisopliae (Metschn.) Sorokïn (Hypocreales: Clavicipitaceae) in the form of bait or sprayed in the nest, or the application of plant mulch in the nest using Tithonia diversifolia (Hemsley) A. Gray (Asterales: Asteraceae) or Canavalia ensiformis L. DC. (Fabales: Fabaceae). Because of variations in the efficacy data between laboratory and field tests, we are in favor of evaluating these control methods during field studies with different leaf-cutting ant species and under different environmental conditions. These methods should adopt experimental arrangements that are appropriate for local socioeconomic conditions adapted for farmers.
Painless osteoid osteoma of the distal phalanx of a toe
Authors: Haoudou Romeo , Malghem Jacques , Galant Christine , Docquier Pierre-Louis 
Published: December 2020

Abstract
Osteoid osteoma is a benign bone tumor, found in young subjects with typical intense focal pain, nocturnal exacerbation and favorable response to salicylates. Painless osteoid osteomas are rare and their diagnosis is difficult, especially whether their imaging appearance is not typical. We report the case of a 13-year-old boy with a spontaneous painless lesion of the distal phalanx of a toe. The main symptom was a swelling of the distal portion of the toe with an enlargement of its nail. The radiological aspect was not typical. A computed tomography showed a small lucent bone area within a focal hypertrophy of the phalangeal tuft and an osteoid osteoma was proposed as main diagnosis. The tumor was completely removed and the histopathological examination confirmed the diagnosis of osteoid osteoma. This clinical case shows that painless swelling of a toe may be indicative of an osteoid osteoma.
Revisiting travellers’ diarrhoea justifying antibiotic treatment: prospective study
Authors: Turunen K A , Kantele A ,   Professor of Infectious Diseases
Published: December 2020

AbstractBackgroundAs antimicrobials increase the risk of acquiring multidrug-resistant (MDR) bacteria, unnecessary antibiotics should be avoided for travellers’ diarrhoea (TD). Antibiotics are recommended in TD accompanied by fever or incapacitation (TD justifying use of antibiotics, TDjuAB). Seeking tools for reducing antibiotic use, we explored factors predisposing to TDjuAB and scrutinized antibiotic treatment among those with TDjuAB [TDjuAB(+) subgroup] and those with diarrhoea not justifying antibiotics [TDjuAB(−) subgroup].MethodsWe conducted a study among 370 prospectively recruited visitors to the tropics. Stool samples and questionnaires were collected before and after travel. Enteric pathogens were analysed by qPCR for enteropathogenic (EPEC), enteroaggregative (EAEC), enterotoxigenic (ETEC), enterohaemorrhagic (EHEC) and enteroinvasive (EIEC) E. coli/Shigella, Campylobacter, Salmonella, Yersinia and Vibrio cholerae, and for ETEC’s toxins LT (heat-labile), STh (human heat-stable) and STp (porcine heat-stable). TD was defined by the WHO criteria and TDjuAB as diarrhoea accompanied by fever, and/or disrupting or preventing daily activities. Multivariable analysis was applied—separately for travel-related factors and pathogens—to identify risk factors for TDjuAB(+).ResultsAmong the 370 travellers, TD was contracted by 253 (68%), categorized as TDjuAB(+) in 93/253 (37%) and TDjuAB(−) in 160/253 (63%) of the cases. Antibiotics were used for TD by 41% in TDjuAB(+) and by 7% in the TDjuAB(−) group. Relative risk ratios (RRR)s are presented for both the TDjuAB(+) and the TDjuAB(−) groups. TDjuAB(+) was associated with long travel duration and young age. Among the 298 subjects not having taken antibiotics, increased RRRs were found e.g. for findings of Campylobacter coli/jejuni and ETEC’s STh toxin.ConclusionsThe first to analyse risk factors for TDjuAB, our study presents RRRs for demographic and behavioural factors and for various pathogens. Only less than half of those in the TDjuAB(+) group took antibiotics, which demonstrates that most cases meeting the current criteria recover without antimicrobial treatment.
Posterior Surgical Approach for Ventral Cervical Spinal Cord Herniation: 2-Dimensional Operative Video
Authors: Diaz Anthony , Burks S Shelby , Fisher Richard , Levi Allan D 
Published: December 2020

Abstract
Spinal cord herniation (SCH) is a rare condition that is typically of idiopathic origin. Although SCH is mostly found in the thoracic region because of a dural defect, there are some reports of cervical SCH following surgery or trauma.
1-3
Spinal cord tethering can be a result of SCH or as a standalone issue.
4,5
These conditions can lead to progressive neurological deficits, including numbness, gait disturbances, and decreased muscle strength, requiring surgical correction. There are limited reports of surgical procedures for ventral SCHs. Several reports exist using a ventral approach for intradural tumors, but it is not commonly employed because of the inability to obtain adequate dural closure.
6
Much of the literature on SCH comes from idiopathic and congenital cases in the thoracic spine.
7,8
Posterior and posterolateral approaches for a ventral thoracic SCH have been described, as well as an anterior approach for a ventral cervical SCH.
9-12
In this video, we describe a posterior approach for a ventral cervical SCH. A 38-yr-old male presented with progressive cervical myelopathy 9 yr after a C2-C3 schwannoma resection requiring an anterior approach and corpectomy of C3 with partial corpectomies of C2 and C4. A preoperative magnetic resonance imaging showed a ventrally herniated spinal cord at the top of the C3 vertebral body and below the C4 vertebral body. Informed consent was obtained. The posterior surgical approach involved a C1-C5 laminectomy, sectioning the dentate ligament, ventral cord untethering, removal of residual tumor, and placement of a ventral sling. A significant improvement in sensory and motor function was observed postoperatively.
Surgical Relevance of Pediatric Anterior Clinoid Process Maturation for Anterior Skull Base Approaches
Authors: Rennert Robert C , Brandel Michael G , Steinberg Jeffrey A , Martin Joel R , Gonda David D , Fukushima Takanori , Day John D , Khalessi Alexander A , Levy Michael L 
Published: December 2020

Abstract

BACKGROUND
Removal of the anterior clinoid process (ACP) can expand anterior skull base surgical corridors. ACP development and anatomical variations are poorly defined in children.

OBJECTIVE
To perform a morphometric analysis of the ACP during pediatric maturation.

METHODS
Measurements of ACP base thickness (ACP-BT), midpoint thickness (ACP-MT), length (ACP-L), length from optic strut to ACP tip (ACP-OS), pneumatization (ACP-pneumo), and the presence of an ossified carotico-clinoid ligament (OCCL) or interclinoid ligament (OIL) were made from high-resolution computed-tomography scans from 60 patients (ages 0-3, 4-7, 8-11 12-15, 16-18, and >18 yr). Data were analyzed by laterality, sex, and age groups using t-tests and linear regression.

RESULTS
There were no significant differences in ACP parameters by laterality or sex, and no significant growth in ACP-BT or ACP-MT during development. From ages 0-3 yr to adult, mean ACP-L increased 49%, from 7.7 to 11.5 mm. The majority of ACP-L growth occurred in 2 phases between ages 0-3 to 8-11 and ages 16-18 to adult. Conversely, ACP-OS was stable from ages 0-3 to 8-11 but increased by 63% between ages 8-11 to adult. Variations in ACP morphology (OCCL/OIL/ACP-pneumo) were found in 15% (9/60) of scans. OCCL and OIL occurred in patients as young as 3 yrs, whereas ACP-pneumo was not seen in patients younger than 11 yrs.

CONCLUSION
The ACP demonstrates stable thickness and a complex triphasic elongation and remodeling pattern with development, the understanding of which may facilitate removal in patients <12. Clinically relevant ACP anatomic variations can occur at any age.
Combined Anterior Transmaxillary (Caldwell-Luc) With an Endoscopic Endonasal Transpterygoid Approach for Resection of a Large Juvenile Nasopharyngeal Angiofibroma: 2-Dimensional Operative Video
Authors: Cohen-Cohen Salomon , Carlstrom Lucas P , Janus Jeffrey R , Van Gompel Jamie J 
Published: December 2020

Abstract
Juvenile nasopharyngeal angiofibroma (JNA) is a highly vascular benign tumor that originates in the sphenopalatine foramen and often spreads to adjacent compartments.
1
Microsurgical resection with preoperative embolization remains the treatment of choice.
2
We present a case of a large JNA involving multiple compartments. The patient is a 20-yr-old male who presented with long-term right nasal congestion. The MRI demonstrated a large enhancing mass that extended from the right nasal cavity and nasopharynx into the right pterygopalatine fossa (PPF), infratemporal fossa (ITF), and parapharyngeal space. Preoperative angiogram for embolization showed a highly vascular tumor with blood supply mainly from the internal maxillary artery and about 10% from a persistent mandibular branch of the internal carotid artery. Based on the UPMC JNA staging system, this tumor was a stage IV.
2
A combined anterior transmaxillary (Caldwell-Luc) with an endoscopic endonasal transpterygoid approach was performed. The addition of the anterior transmaxillary approach increases the surgical freedom for traditional bipolar devices and improves the view and trajectory to more lateral structures like the PPF and ITF.
3
Gross total resection was achieved without complications. The patient was discharged home with a partial V2 numbness (right superior gum) that improved with time. The endoscopic endonasal approach is a safe and effective technique even for large JNA. A multidisciplinary team consisting of an interventional radiologist, a skull base neurosurgeon, and an otorhinolaryngologist with expertise in endoscopic surgery may play a role for optimal surgical results. The patient consented for the procedure and for the video production.
Minimally Invasive Endoscopy for Acute Subdural Hematomas: A Report of 3 Cases
Authors: Khattar Nicolas K , McCallum Abigail P , Fortuny Enzo M , White Andrew C , Ball Tyler J , Adams Shawn W , Meyer Kimberly S , Wei George , John Kevin D , Bak Esther , Sieg Emily P , Ding Dale , James Robert F 
Published: December 2020

Abstract

BACKGROUND
Acute subdural hematomas (aSDHs) occur in approximately 10% to 20% of all closed head injury and represent a significant cause of morbidity and mortality in traumatic brain injury patients. Conventional craniotomy is an invasive intervention with the potential for excess blood loss and prolonged postoperative recovery time.

OBJECTIVE
To evaluate the outcomes of minimally invasive endoscopy for evacuation of aSDHs in a pilot feasibility study.

METHODS
We retrospectively reviewed the records of consecutive patients with aSDHs who underwent surgical treatment at our institution with minimally invasive endoscopy using the Apollo/Artemis Neuro Evacuation Device (Penumbra, Alameda, California) between April 2015 and July 2018.

RESULTS
The study cohort comprised three patients. The Glasgow Coma Scale on admission was 15 for all 3 patients, median preoperative hematoma volume was 49.5 cm3 (range 44-67.8 cm3), median postoperative degree of hematoma evacuation was 88% (range 84%-89%), and median modified Rankin Scale at discharge was 1 (range 0-3).

CONCLUSION
Endoscopic evacuation of aSDHs can be a safe and effective alternative to craniotomy in appropriately selected patients. Further studies are needed to refine the selection criteria for endoscopic aSDH evacuation and evaluate its long-term outcomes.
A Safe and Effective Posterior Intra-Articular Distraction Technique to Treat Congenital Atlantoaxial Dislocation Associated With Basilar Invagination: Case Series and Technical Nuances
Authors: Chen Zan , Duan Wanru , Chou Dean , Guan Jian , Liu Zhenlei , Jian Qiang , Zhang Boyan , Bo Xuefeng , Jian Fengzeng 
Published: December 2020

Abstract

BACKGROUND
The management of atlantoaxial dislocation (AAD) associated with basilar invagination (BI) is challenging, and traditional posterior-only approaches lack the ability to release the anterior soft tissue resulting in unsatisfactory reduction. Furthermore, vertebral artery anomalies and deformed anatomy increase surgical risks.

OBJECTIVE
To introduce a safe and efficient technique to reduce congenital AAD and BI through a single-stage posterior-only approach.

METHODS
A total of 65 patients with AAD and concomitant BI who had congenital osseous abnormalities were retrospectively analyzed. All patients had anterior soft tissue released through a posterior-only approach, followed by intra-facet cages implantation, cantilever correction, and instrumentation. Clinical results were measured using the Japanese Orthopedic Association (JOA) scale, and radiographic measurements included the atlanto-dental interval, the distance of odontoid tip above Chamberlain's line, clivus-canal angle (CCA), and syrinx length. Paired t-tests were used to compare preoperative and postoperative measurements.

RESULTS
The mean JOA score increased from 10.98 to 14.40 at 1-yr follow-up. Complete reduction of AAD and BI was achieved in 48 patients (73.8%). The mean CCA improved from 115° preoperatively to 129° postoperatively. Reduction of syrinx size was observed in 14 patients at 1 wk and in 35 patients 1 yr after surgery. All patients achieved bony fusion.

CONCLUSION
Posterior intra-articular distraction followed by cage implantation and cantilever correction can achieve complete reduction in most cases of congenitally anomalous AAD associated with BI.
Surgical Site Infection, Readmission, and Reoperation After Posterior Long Segment Fusion
Authors: Shlobin Nathan A. , Cloney Michael B. , Hopkins Benjamin S. , Kesavabhotla Kartik , Goergen Jack A. , Driscoll Conor , Svet Mark , Kelsten Max F. , Koski Tyler , Dahdaleh Nader S. 
Published: December 2020

Study Design.
Retrospective case series.

Objective.
We sought to identify risk factors associated with surgical site infection (SSI) after posterior long segment spinal fusion (PLSF).

Summary of Background Data.
Patients who undergo PLSF may be at elevated risk of SSI. Identifying factors associated with SSI in these operations can help risk stratify patients and tailor management.

Methods.
We analyzed PLSFs—seven or more levels—at our institution from 2000 to 2015. Data on patients’ clinical characteristics, procedural factors, and antimicrobial management were collected. Multivariable analysis identified factors independently associated with outcomes of interest.

Results.
In 628 cases, SSI was associated with steroid use (P = 0.024, odds ratio [OR] = 2.54) and using cefazolin (P < 0.001, OR = 4.37) or bacitracin (P = 0.010, OR 3.49) irrigation, as opposed to gentamicin or other irrigation. Gram-positive infections were more likely with staged procedures (P = 0.021, OR 4.91) and bacitracin irrigation (P < 0.001, OR = 17.98), and less likely with vancomycin powder (P = 0.050, OR 0.20). Gram-negative infections were more likely with a history of peripheral arterial disease (P = 0.034, OR = 3.21) or cefazolin irrigation (P < 0.001, OR 25.47). Readmission was more likely after staged procedures (P = 0.003, OR = 3.31), cervical spine surgery (P = 0.023, OR = 2.28), or cefazolin irrigation (P = 0.039, OR = 1.85). Reoperation was more common with more comorbidities (P = 0.022, OR 1.09), staged procedures (P < 0.001, OR = 4.72), cervical surgeries (P = 0.013, OR = 2.36), more participants in the surgery (P = 0.011, OR = 1.06), using cefazolin (P < 0.001, OR = 3.12) or bacitracin (P = 0.009, OR = 3.15) irrigation, and higher erythrocyte sedimentation rate at readmission (P = 0.009, OR = 1.04). Washouts were more likely among patients with more comorbidities (P = 0.013, OR = 1.16), or who used steroids (P = 0.022, OR = 2.92), and less likely after cervical surgery (P = 0.028, OR = 0.24). Instrumentation removal was more common with bacitracin irrigation (p = 0.013, OR = 31.76).

Conclusion.
Patient factors, whether a procedure is staged, and choice of antibiotic irrigation affect the risk of SSI and ensuing management required.

Level of Evidence: 4
Surgical Correction of Scoliosis in Children with Severe Congenital Heart Disease and Palliated Single Ventricle Physiology
Authors: Cohen Lara L. , Przybylski Robert , Marshall Audrey C. , Emans John B. , Hedequist Daniel J. 
Published: December 2020

Study Design.
Case series.

Objective.
In this study we focus on this group, and describe the largest cohort to date of single ventricle patients undergoing surgical correction of scoliosis at a single institution.

Summary of Background Data.
Outcomes of spinal surgery for patients with congenital heart disease (CHD) have evolved and most affected patients have uncomplicated procedures. The risk of perioperative complications remains highest in patients with single ventricle (“Fontan") physiology.

Methods.
We reviewed patients with single ventricle CHD and operative scoliosis repair over a 25-year span. Patients who had undergone a Fontan, bidirectional Glenn, and/or Kawashima procedure before operative scoliosis repair were included. Patients were excluded if they lacked preoperative cardiac care and/or sufficient medical history at our institution.

Results.
Twenty-three patients were included. The average age at surgery was 13.6 years (range, 5–23). Seventy percent of the cohort was female (16/23). The majority of patients underwent a Fontan before scoliosis surgery (20/23, 87%). Patients without intraoperative tranexamic acid (TXA) had a 67% complication rate (8/12) versus 36% (4/11) in those with intraoperative TXA (P = 0.29). There was a significant difference in estimated blood loss by weight (cc/kg) between non-TXA and TXA patients (P = 0.016). Twelve patients experienced complications (52%), all of which occurred postoperatively. There were no deaths, cerebrovascular events, adverse perioperative cardiac or hemodynamic complications, or wound infections. Using the Clavien-Dindo-Sink classification for postoperative complications, four patients had serious adverse events, including one permanent neurologic deficit.

Conclusion.
Spinal surgery for scoliosis has been performed in selected patients with single ventricle physiology at a single institution without mortality for 25 years. Operative blood loss may be reduced by routine use of TXA. Complications occur most commonly in the postoperative period, and can include pleural effusion.

Level of Evidence: 4
Thirty- and 90-day Readmissions After Spinal Surgery for Spine Metastases
Authors: Elsamadicy Aladine A. , Koo Andrew B. , David Wyatt B. , Zogg Cheryl K. , Kundishora Adam J. , Hong Christopher S. , Kuzmik Gregory A. , Gorrepati Ramana , Coutinho Pedro O. , Kolb Luis , Laurans Maxwell , Abbed Khalid 
Published: December 2020

Study Design.
Retrospective cohort study.

Objective.
The aim of this study was to investigate differences in 30- and 90-day readmissions for spine metastases treated with decompression and/or fusion spine surgery in a nationwide readmission database.

Summary of Background Data.
Patients with metastases to the spine represent a particularly vulnerable patient group that may encounter frequent readmissions. However, the 30- and 90-day rates for readmission following surgery for spine metastases have not been well described.

Methods.
The Nationwide Readmission Database years 2013 to 2015 was queried. Patients were grouped by no readmission (non-R), readmission within 30 days (30-R), and readmission within 31 to 90 days (90-R). Weighted multivariate analysis assessed impact of treatment approach and clinical factors associated with 30- and 90-day readmissions.

Results.
There were a total of 4423 patients with a diagnosis of spine metastases identified who underwent spine surgery, of which 1657 (37.5%) encountered either a 30-or 90-day unplanned readmission (30-R: n = 1068 [24–.1%]; 90-R: n = 589 [13.3%]; non-R: n = 2766). The most prevalent inpatient complications observed were postoperative infection (30-R: 16.3%, 90-R: 14.3%, non-R: 11.5%), acute post-hemorrhagic anemia (30-R: 13.4%, 90-R: 14.2%, non-R: 14.5%), and genitourinary complication (30-R: 5.7%, 90-R: 2.9%, non-R: 6.2%). The most prevalent 30-day and 90-day reasons for admission were sepsis (30-R: 10.2%, 90-R: 10.8%), postoperative infection (30-R: 13.7%, 90-R: 6.5%), and genitourinary complication (30-R: 3.9%, 90-R: 4.1%). On multivariate regression analysis, surgery type, age, hypertension, and renal failure were independently associated with 30-day readmission; rheumatoid arthritis/collagen vascular diseases, and coagulopathy were independently associated with 90-day readmission.

Conclusion.
In this study, we demonstrate several patient-level factors independently associated with unplanned hospital readmissions after surgical treatment intervention for spine metastases. Furthermore, we find that the most common reasons for readmission are sepsis, postoperative infection, and genitourinary complications.

Level of Evidence: 3