bluuebunny/crossref_metadata_2025_split huggingface dataset:
Convex Quadratic Equation
Authors: Lin Li-Gang , Liang Yew-Wen , Hsieh Wen-Yuan 
Published: August 2020

AbstractTwo main results (A) and (B) are presented in algebraic closed forms. (A) Regarding the convex quadratic equation, an analytical equivalent solvability condition and parameterization of all solutions are formulated, for the first time in the literature and in a unified framework. The philosophy is based on the matrix algebra, while facilitated by a novel equivalence/coordinate transformation (with respect to the much more challenging case of rank-deficient Hessian matrix). In addition, the parameter-solution bijection is verified. From the perspective via (A), a major application is re-examined that accounts for the other main result (B), which deals with both the infinite and finite-time horizon nonlinear optimal control. By virtue of (A), the underlying convex quadratic equations associated with the Hamilton–Jacobi equation, Hamilton–Jacobi inequality, and Hamilton–Jacobi–Bellman equation are explicitly solved, respectively. Therefore, the long quest for the constituent of the optimal controller, gradient of the associated value function, can be captured in each solution set. Moving forward, a preliminary to exactly locate the optimality using the state-dependent (resp., differential) Riccati equation scheme is prepared for the remaining symmetry condition.
Advanced exact synthesis of Clifford+T circuits
Authors: Niemann Philipp , Wille Robert , Drechsler Rolf 
Published: August 2020

AbstractQuantum systems provide a new way of conducting computations based on the so-called qubits. Due to the potential for significant speed-ups, this field received significant research attention in recent years. The Clifford+T library is a very promising and popular gate library for these kinds of computations. Unlike other libraries considered so far, it consists of only a small number of gates for all of which robust, fault-tolerant realizations are known for many technologies that seem to be promising for large-scale quantum computing. As a consequence, (logic) synthesis of Clifford+T quantum circuits became an important research problem. However, previous work in this area has several drawbacks: Corresponding approaches are either only applicable to very small quantum systems or lead to circuits that are far from being optimal. The latter is mainly caused by the fact that current synthesis realizes the desired circuit by a local, i.e., column-wise, consideration of the underlying unitary transformation matrix to be synthesized. In this paper, we analyze the conceptual drawbacks of this approach and propose to overcome them by taking a global view of the matrices and perform a separation of concerns regarding individual synthesis steps. We precisely describe a corresponding algorithm as well as its efficient implementation on top of decision diagrams. Experimental results confirm the resulting benefits and show improvements of up to several orders of magnitudes in costs compared to previous work.
Profile of patients diagnosed with acute venous thromboembolism in routine practice according to age and renal function: RE-COVERY DVT/PE study
Authors: Ageno Walter , Casella Ivan B. , Chee Kok Han , Schellong Sebastian , Schulman Sam , Singer Daniel E. , Desch Marc , Tang Wenbo , Voccia Isabelle , Zint Kristina , Goldhaber Samuel Z. 
Published: August 2020

Abstract
In randomized clinical trials (RCTs) of nonvitamin K antagonist oral anticoagulants (NOACs) for acute venous thromboembolism (VTE), ~ 12–13% of patients were elderly and ~ 26% had mild-to-moderate renal impairment. Observational studies are not restricted by the selection and treatment criteria of RCTs. In this ancillary analysis of the RE-COVERY DVT/PE global observational study, we aimed to describe patient characteristics, comorbidities, and anticoagulant therapy for subgroups of age (< or ≥ 75 years) and renal impairment (creatinine clearance [CrCl; estimated with Cockcroft–Gault formula] < 30 [severe], 30 to < 50 [moderate], 50 to < 80 [mild], ≥ 80 [normal] mL/min). Of 6095 eligible patients, 25.3% were aged ≥ 75 years; 38.2% (1605/4203 with CrCl values) had mild-to-moderate renal impairment. Comorbidities were more common in older patients (73.9% aged ≥ 75 vs. 58.1% < 75 years) and in those with mild or moderate versus no renal impairment (75.9%, 80.9%, and 59.3%, respectively). At hospital discharge or 14 days after diagnosis (whichever was later), most patients (53.7% and 55.1%, respectively) in both age groups received NOACs; 20.8% and 23.4%, respectively, received vitamin K antagonists, 19.0% and 21.8% parenteral therapy, 2.3% and 3.8% other anticoagulant treatments. Use of NOACs decreased with worsening renal impairment (none 58.5%, moderate 49.6%, severe 25.7%) and, in younger versus older patients with moderate renal impairment (33.1% vs. 56.1%). In routine practice, there are more elderly and renally impaired patients with VTE than represented in RCTs. Decreasing renal function, but not older age, was associated with less NOAC use. Clinical Trial Registration: http://www.clinicaltrials.gov. Unique identifier: NCT02596230.

Graphic abstract
Decreasing renal function, particularly in the subgroup with CrCl < 30 mL/min, but not older age, was associated with less use of nonvitamin K antagonist oral anticoagulants (NOACs). Nevertheless, more than half of the older patients with moderate renal impairment received a NOAC as their oral anticoagulant.
The preparation of calcium phosphate adsorbent from natural calcium resource and its application for copper ion removal
Authors: Kalbarczyk Marta , Szcześ Aleksandra , Sternik Dariusz 
Published: August 2020

AbstractUsing the hen eggshells (biowaste) as a source of calcium and an environmentally friendly approach, the nanopowder composed of 74% of hydroxyapatite (HA) and 26% of β–tricalcium phosphate (β-TCP) was obtained. Due to the maximum reduction of the stages associated with the use of chemicals and energy, this method can be considered as economically and environmentally friendly. A well-developed surface area and the negative zeta potential at pH above 3.5 indicate good adsorption properties of this material. The obtained material shows high adsorption capacity towards Cu2+ions, i.e. 105.4 mg/g at pH 5. Good fit of the Langmuir adsorption model and the pseudo-second-order kinetic model may indicate chemical adsorption probably due to the electrostatic interactions between the Cu2+cations and the negatively charged phosphate and hydroxyl groups on the material surface.
Psychische Gesundheit bei Referendaren
Authors: Darius Sabine , Bunzel Kathleen , Ehms-Ciechanowicz Ewa , Böckelmann Irina 
Published: August 2020

ZusammenfassungHintergrundLehrkräfte sind in ihrem Beruf verschiedenen Belastungen ausgesetzt, aufgrund derer es zu Fehlbeanspruchungen kommen kann. Weniger bekannt ist dagegen die gesundheitliche Situation bei Referendaren.Ziel der StudieEs war zu klären, ob und inwieweit die psychische Gesundheit in Abhängigkeit der Referendariatsphase bei Referendaren beeinträchtigt ist, um den Bedarf an Präventionsmaßnahmen einschätzen zu können.MethodikFür die Studie wurden 131 Referendare im Alter von 28,1 ± 3,7 Jahren aus Magdeburg und Umgebung befragt. 72 von ihnen befanden sich in der Einstiegsphase des Referendariats, 51 in der Qualifizierungsphase und 8 in der Prüfungsphase. Die psychische Gesundheit wurde mit der Kurzversion des „General Health Questionnaire 12“ (GHQ-12), die Anstrengungsbereitschaft mit einem Teil des Effort-reward-imbalance(ERI)-Fragebogens und das Burnout-Risiko mit dem Maslach-Burnout-Inventar (MBI) erhoben. Zusätzlich wurden arbeitsbezogene Verhaltens- und Erlebensmuster (AVEM) erfasst.ErgebnisseBei 41 (31,3 %) Referendaren war die psychische Gesundheit bereits beeinträchtigt, sie wiesen auch einige Burnout-Symptome auf. In der Qualifizierungsphase war die emotionale Erschöpfung stärker als in der Einstiegsphase. Mehrheitlich waren gesundheitsförderliche Muster G und S vertreten, bei etwa einem Drittel der Referendare überwogen die gesundheitsgefährdenden Verhaltensmuster A und B.SchlussfolgerungDa sich die psychische Gesundheit bereits im Referendariat bei etwa einem Drittel der Referendare beeinträchtigt gezeigt hat, müssen präventive Maßnahmen als Pflichtveranstaltung in das Studium integriert werden, um die Gesundheit der Referendare zu erhalten.
Single Anastomosis Duodeno-ileostomy (SADI-S) Versus One Anastomosis Gastric Bypass (OAGB-MGB) as Revisional Procedures for Patients with Weight Recidivism After Sleeve Gastrectomy: a Comparative Analysis of Efficacy and Outcomes
Authors: Bashah Moataz , Aleter Ammar , Baazaoui Jawher , El-Menyar Ayman , Torres Antonio , Salama Asaad 
Published: August 2020

Abstract
Purpose
Many revisional procedures are available for unsuccessful laparoscopic sleeve gastrectomy (LSG) in patients with complications or weight recidivism. Single anastomosis duodeno-ileal bypass (SADI-S) and one anastomosis gastric bypass (OAGB-MGB) are two revisional procedures to address the problem of weight recidivism. We aimed to evaluate the efficacy and outcomes of the 2 revisional approaches (SADI-S vs. OAGB-MGB).

Materials and Methods
A retrospective analysis of prospectively collected database of patients who underwent SADI-S or OAGB-MGB as a revisional procedure for weight recidivism after primary LSG with a minimum 1-year follow-up. Weight loss, comorbidities, nutritional deficiencies, complications, and outcomes were compared in the 2 procedures.

Results
Ninety-one patients were included in the study (42 SADI-S and 49 OAGB-MGB). There was a significant weight loss (total weight loss percentage, TWL%) at 1-year follow-up observed for SADI-S when compared to OAGB-MGB (23.7 ± 5.7 vs. 18.7 ± 8.5, p = 0.02). However, this difference was not statistically significant at 18 months (26.4 ± 7.3 vs. 21.2 ± 11.0, p = 0.25). Remission of comorbidities (diabetes mellitus and hypertension) was comparable. Although OAGB-MGB had higher complication rate than SADI-S, the difference was not statistically significant (p = 0.39). No mortality was reported in the study groups.

Conclusion
Both SADI-S and OAGB-MGB are effective and safe revisional procedures for weight regain after LSG. The short-term outcomes are comparable; however, SADI-S is associated with less upper gastrointestinal complications and could be a better option for patients suffering from GERD post-LSG. Moreover, the underlying bile reflux may get worse with OAGB-MGB. However, further prospective larger studies are needed.
Gastritis: An Update in 2020
Authors: Rugge Massimo , Sugano Kentaro , Sacchi Diana , Sbaraglia Marta , Malfertheiner Peter 
Published: August 2020

Abstract
Purpose of review
The gastritis constellation includes heterogeneous clinicopathological entities, among which long-standing, non-self-limiting gastritis, mainly due to Helicobacter pylori infection, has been epidemiologically, biologically, and clinically linked to gastric cancer development (i.e. “inflammation-associated cancer”). This review illustrates the updated criteria applied in the taxonomy of gastritis (Kyoto classification), elucidates the biological rationale for endoscopy biopsy sampling (heterogeneity of gastric mucosa), and finally reports the results of long-term follow-up studies supporting the reliability of biopsy-based gastritis staging as predictor of gastritis-associated cancer risk.

Recent findings
By assuming gastric atrophy as the “cancerization field” where (non-syndromic) gastric cancer mostly develops, recent long-term follow-up studies consistently demonstrate the prognostic impact of the gastritis OLGA staging system.

Summary
Helicobacter pylori eradication is the leading strategy in the primary prevention of gastric cancer. In a multidisciplinary dimension of secondary cancer prevention, the OLGA staging system reliably ranks the patient-specific cancer risk, thus providing the clinical rationale for a tailored follow-up strategy.
The 2020 national diagnostic reference levels for nuclear medicine in Japan
Authors: Abe Koichiro , Hosono Makoto , Igarashi Takayuki , Iimori Takashi , Ishiguro Masanobu , Ito Teruo , Nagahata Tomomasa , Tsushima Hiroyuki , Watanabe Hiroshi 
Published: August 2020

AbstractThe diagnostic reference levels (DRLs) are one of several effective tools for optimizing nuclear medicine examinations and reducing patient exposure. With the advances in imaging technology and alterations of examination protocols, the DRLs must be reviewed periodically. The first DRLs in Japan were established in 2015, and since 5 years have passed, it is time to review and revise the DRLs. We conducted a survey to investigate the administered activities of radiopharmaceuticals and the radiation doses of computed tomography (CT) in hybrid CT accompanied by single photon emission computed tomography (SPECT)/CT and positron emission tomography (PET)/CT. We distributed a Web-based survey to 915 nuclear medicine facilities throughout Japan and survey responses were provided by 256 nuclear medicine facilities (response rate 28%). We asked for the facility's median actual administered activity and median radiation dose of hybrid CT when SPECT/CT or PET/CT was performed for patients with standard habitus in the standard protocol of the facility for each nuclear medicine examination. We determined the new DRLs based on the 75th percentile referring to the 2015 DRLs, drug package inserts, and updated guidelines. The 2020 DRLs are almost the same as the 2015 DRLs, but for the relatively long-lived radionuclides, the DRLs are set low due to the changes in the Japanese delivery system. There are no items set higher than the previous values. Although the DRLs determined this time are roughly equivalent to the DRLs used in the US, overall they tend to be higher than the European DRLs. The DRLs of the radiation dose of CT in hybrid CT vary widely depending on each imaging site and the purpose of the examination.
Effects of Wood Ash-Based Alkaline Treatment on Nitrogen, Carbon, and Phosphorus Availability in Food Waste and Agro-Industrial Waste Digestates
Authors: Moure Abelenda Alejandro , Semple Kirk T. , Lag-Brotons Alfonso Jose , Herbert Ben M. J. , Aggidis George , Aiouache Farid 
Published: August 2020

AbstractHandling of food waste and agro-industrial waste digestates, and fly and bottom wood ashes represents an economic and environmental problem for society and industries where they are produced due to the requirement of large capacity storage facilities with special conditions. Since both materials contain important nutrients for crops, two different blending combinations were examined as potential slow-release fertilizers to enhance the circular economy. High share of biomass ashes were selected aiming the chemical alkaline stabilization of the digestates. The concentrations of nitrogen, carbon, and phosphorus in the water-soluble extract of the blends, which was obtained by adding ten parts of milli-Q® per each part of sample and subsequent solid–liquid separation, were measured during a 10-h incubation at 22 °C and 100 rpm. The volatilization of ammonia was the main route of losing nitrogen, with the greatest rate of volatilization at the time of blending and approximately 50 mg NH3-N/kg blend/hour by the end of the incubation. The hydrolysis taking place at alkaline pH was found responsible of the conversion of organic nitrogen to ammoniacal nitrogen and of the increase of the amount of water-soluble carbon, which rose progressively during the incubation. The release of CO2 was prevented by the high pH (> 10) of the blends. The drop in the concentration of water-soluble orthophosphate at the time of preparing the mixtures was driven by adsorption onto the ashes. The desorption of some of the orthophosphate was found to be inversely related to the amount of ashes added to the digestates.
Graphic Abstract
Improvements in Mindfulness Facets Mediate the Alleviation of Burnout Dimensions
Authors: Kinnunen Sanna M. , Puolakanaho Anne , Tolvanen Asko , Mäkikangas Anne , Lappalainen Raimo 
Published: August 2020

Abstract
Objectives
While interventions using mindfulness have been effective in treating burnout, the mechanisms of change need more research. This study investigated which of five mindfulness facets (observing, describing, acting with awareness, non-judging, and non-reacting) mediated the intervention effects on three burnout dimensions (exhaustion, cynicism, and reduced professional efficacy) during an 8-week mindfulness-, acceptance-, and value-based (MAV) intervention and a 10-month follow-up.

Methods
The participants were a heterogeneous sample of employees suffering from burnout (n = 202, 80% women, mean age = 47.5 years). Latent change score modeling was conducted for each combination of the mindfulness facets and the burnout dimensions. Confidence intervals were calculated for the coefficients in the models.

Results
The modeling results showed that mindfulness improvement during the intervention mediated burnout alleviation during both the intervention and the 10-month follow-up. A large spread of mindfulness facets mediated changes in all the burnout dimensions during the intervention (all for cynicism, all except describing for exhaustion, and all except observing for reduced professional efficacy). The improvement in non-judging skills mediated the reductions in all burnout dimensions during the follow-up. For exhaustion, it was the only significant mediator during the follow-up, whereas for cynicism and reduced professional efficacy, describing and observing were additional mediators.

Conclusions
Improving mindfulness facets using a MAV intervention had significant long-term effects on burnout in this study. Non-judging is possibly the most important mindfulness facet to improve in burnout interventions, given that it mediated the changes in all burnout dimensions during both the intervention and 10-month follow-up.
Motor oil degradation during urban cycle road tests
Authors: Wei Lei , Duan Haitao , Jin Yongliang , Jia Dan , Cheng Bingxue , Liu Jianfang , Li Jian 
Published: August 2020

AbstractSeveral civilian vehicles in China operate in urban traffic conditions and have their motor oil changed every 5,000 km. This study investigates the variations in oil properties after servicing at 5,000 km, based on systematic road tests (including a repeated test, a parallel test, and a new vehicle test). The physicochemical properties, changes in components, oxidation stability, detergent-dispersant performance, and tribological properties of motor oils were analyzed. The results showed that the total acid number (TAN) of oils increased with the operation mileage, by up to 1.41 mgKOH/g. The total base number (TBN) decreased after the road tests were completed, and the decrease was less than 44.6%. The kinematic viscosity (KV) of most oils decreased initially and then stabilized in the middle stage, before starting to increase later in the experiment. The change in KV at 100 °C was less than 15.96%. The oxidation onset temperature (OOT) of the oils diminished gradually with the operation mileage. All OOT values of the used oils were higher than 210 °C. A spot test indicated that the used oils retained their detergent-dispersant performance to an appropriate extent. The four-ball wear scar diameters and friction coefficient of the used oils did not increase significantly after the road tests were completed. This study can serve as a reference for end-users when changing motor oils.
Whose Cultural Objects? Introducing Heritage Title for Cross-Border Cultural Property Claims
Authors: Campfens Evelien 
Published: August 2020

AbstractCultural objects have a special, protected, status because of their intangible ‘heritage’ value to people, as symbols of an identity. This has been so since the first days of international law and, today, there is an extensive legal framework to protect cultural objects and to prohibit looting. Despite this, for as long as demand exists and profits are high, cultural objects continue to be looted, smuggled and traded. At some point, their character tends to change from protected heritage in an original setting to valuable art and commodity in the hands of new possessors. In this new setting, the legal status of such objects most likely will be a matter of ownership and the private law regime in the country where they happen to end up. This article suggests that, irrespective of the acquired rights of others, original owners should still be able to rely on a ‘heritage title’ if there is a continuing cultural link. The term aims to capture the legal bond between cultural objects and people, distinct from ownership, and is informed by international cultural heritage and human rights law norms. The proposition is that, whilst ownership interests are accounted for in national private law, legal tools are lacking to address heritage interests and identity values that are acknowledged in international law. Neither the existing legal framework for the art trade, based on the 1970 UNESCO Convention, nor regular ownership concepts appear particularly suited to solve title issues over contested cultural objects. The notion of ‘heritage title’ in a human rights law approach can act as a bridge in that regard.
Developing image analysis pipelines of whole-slide images: Pre- and post-processing
Authors: Smith Byron , Hermsen Meyke , Lesser Elizabeth , Ravichandar Deepak , Kremers Walter 
Published: August 2020

Abstract
Deep learning has pushed the scope of digital pathology beyond simple digitization and telemedicine. The incorporation of these algorithms in routine workflow is on the horizon and maybe a disruptive technology, reducing processing time, and increasing detection of anomalies. While the newest computational methods enjoy much of the press, incorporating deep learning into standard laboratory workflow requires many more steps than simply training and testing a model. Image analysis using deep learning methods often requires substantial pre- and post-processing order to improve interpretation and prediction. Similar to any data processing pipeline, images must be prepared for modeling and the resultant predictions need further processing for interpretation. Examples include artifact detection, color normalization, image subsampling or tiling, removal of errant predictions, etc. Once processed, predictions are complicated by image file size – typically several gigabytes when unpacked. This forces images to be tiled, meaning that a series of subsamples from the whole-slide image (WSI) are used in modeling. Herein, we review many of these methods as they pertain to the analysis of biopsy slides and discuss the multitude of unique issues that are part of the analysis of very large images.
Travel-screening documentation to enable the “Identify–Isolate–Inform” framework for emerging infectious diseases: It’s all in the details
Authors: Sánchez Sarimer M. , Searle Eileen F. , Rubins David , Dutta Sayon , Ware Winston , Biddinger Paul D. , Shenoy Erica S. 
Published: August 2020

AbstractThe early phase of the coronavirus disease 2019 (COVID-19) pandemic and ongoing efforts for mitigation underscore the importance of universal travel and symptom screening. We analyzed adherence to documentation of travel and symptom screening through a travel navigator tool with clinical decision support to identify patients at risk for Middle East Respiratory Syndrome.