bluuebunny/crossref_metadata_2025_split huggingface dataset:
Baduanjin exercise for patients with knee osteoarthritis
Authors: Li Jieying , Yin Shuai , Li Ruiqing , Ge Beibei , Su Kaiqi , Song Xiaolei , Zhang Zhenhua , Chang Yiniu , Feng Xiaodong , Wu Nan 
Published: October 2020

Abstract

Background:
Knee osteoarthritis (KOA) is a common chronic degenerative disorder with an increasingly prevalence among the older individuals and the leading cause of pain in the elderly. Baduanjin, one of the ancient traditional Chinese mind-body exercise routine, has been recognized to have clinical benefits for KOA. We aim to evaluate the efficacy and safety of Baduanjin for patients with KOA through this systematic review and meta-analysis.

Methods:
Four English databases (Cochrane Central Register of Controlled Trials, PubMed, EMBASE, and Web of Science), and 4 Chinese databases (China National Knowledge Infrastructure, Chinese Biomedical Literature Database, Chinese Scientific Journal Database, and Wanfang Database), will be searched from establishment of the database until October 2020. The reference lists and the citation lists of studies meeting the inclusion criteria will also be searched to identify further studies for inclusion. The search languages are English and Chinese. The randomized controlled trials of Baduanjin training for patients with KOA will be included. The primary outcome will be assessed according to the Western Ontario and McMaster Universities Osteoarthritis Index. Meta-analysis will be conducted with the use of RevMan 5.3.

Results:
The results of this research will be submitted to a peer-reviewed publications.

Conclusion:
This systematic review aims to present evidence for whether Baduanjin training is an effective intervention which can improve both physical condition and life quality in patients suffering KOA.

INPLASY registration number:
INPLASY202090051.
Clinical nursing pathway improves the nursing satisfaction in patients with acute cerebral hemorrhage
Authors: Fu Su , Han Hui , Fan Chaofeng , Jiang Yan 
Published: October 2020

Abstract

Background:
Cerebral hemorrhage (CH) is a very common cerebrovascular disorder in clinical practice. More and more studies reported that proper nursing care could promote the rate of treatment, and improve the prognosis after treatment. Clinical nursing pathway (CNP) refers to original nursing mode with good quality, outstanding efficiency, and low treatment spending. Few articles have reported the effect of CNP in patients with acute CH. The program is in urgent need of convinced evidence to prove the reliability. Thus, we perform this randomized controlled trial protocol and hypothesize that CNP is associated with improved outcomes and nursing satisfaction, reduced adverse reactions in patients with acute CH.

Method:
It is a single-center randomized controlled study to be conducted from October 2020 to October 2021. It was admitted via the Ethics Committee of the West China Hospital of Sichuan University (0038842/121). Eighty patients meet diagnostic standards for CH are included. The study group receives the clinical nursing path model. In the control group, patients receive the routine care before and after taking to the hospital. The main outcome contains the Barthel index score, the patient's degree of satisfaction about care, the length of hospital stay, and the risk of complications such as infection, bedsores and gastrointestinal function between the 2 groups. Six months after admission, the functional independence measure and Fugl Meyer score are recorded. All data are analyzed by the IBM SPSS Statistics, version 20 (IBM Corp., Armonk, NY edition).

Results:
Table 1 shows the clinical outcomes between groups.

Conclusion:
CNP may improve the clinical outcomes for patients with acute CH and have a significant value in actual applications.

Trial registration number:
researchregistry6061
Efficacy and safety of traditional Chinese medicinal enemas for treatment of chronic renal failure
Authors: Wu Lihua , Wang Yating , Liu Yu , Wu Ling , Cheng Dan , Jiang Ting , Qu Bo , Lu Hongmei , Yang Ju , Tang Anqi , Li Mingquan 
Published: October 2020

Abstract

Background:
Chronic renal failure (CRF) is a common kidney disease characterized by a slow and progressive decline in kidney function. Clinical practice suggests that traditional Chinese medicinal enemas have a therapeutic effect on CRF. To assess the therapeutic efficacy and safety of traditional Chinese medicinal enemas in treating CRF, we created a protocol for a systematic review to inform future clinical applications.

Methods:
We completed a literature search of all clinical randomized controlled trials evaluating traditional Chinese medicinal enemas on CRF in the following five English and four Chinese databases completed before August 2020: Medline, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Library database, Chinese National Knowledge Infrastructure (CNKI), WANFANE Database, Chinese Scientific and Technological Periodical Database (VIP) and Chinese Biomedical Database (CBM). The primary outcomes evaluated blood urea nitrogen levels, uric acid levels, endogenous creatinine clearance rate, and serum creatinine, and the secondary outcomes included clinical efficacy and adverse effects of treatment. Two independent researchers performed data extraction and quality assessment. RevMan5.3 software was used to assess data quality and bias. This protocol was conducted according to the Preferred Reporting Item for Systematic Review and Meta-analysis Protocol (PRISMA-P) statement.

Results:
This study will provide a rational synthesis of current evidence for traditional Chinese medicinal enemas for the treatment of CRF.

Conclusion:
This study presents evidence on whether traditional Chinese medicinal enemas are an effective and safe intervention for CRF patients.

Registration number:
INPLASY202080052
Surgical treatment and strategy in patients with pressure sores
Authors: Chen Chun-Yu , Chiang I-Han , Ou Kuang-Ling , Chiu Yu-Lung , Liu Hung-Hui , Chang Chun-Kai , Wu Chien-Ju , Chu Tzi-Shiang , Hsu Kuo-Feng , Huang Dun-Wei , Tzeng Yuan-Sheng 
Published: October 2020

Abstract
With aging, pressure ulcers become a common health problem causing significant morbidity and mortality for physically limited or bedridden elderly persons. Here, we present our strategy for such patients. Between August 2010 and March 2019, 117 patients were enrolled. Patient age, etiology, defect size and location, flap reconstruction, outcome, and follow-up period were reviewed. Of these patients, 64 were female and 53 were male, with an age range of 21 to 96 years (mean 75.6). The mean area of defect was 61.5 cm2. The most common etiology was dementia (33.3%), and ulcers were most frequently caused by sacral pressure (70.3%). The commonest surgical treatment was a V–Y advancement flap (50%). The complication rate was 27.5%, including dehiscence and late recurrence. Negative pressure wound therapy could be used if the initial defect was large. V–Y advancement flap is the most frequent surgical treatment for sacral pressure ulcers because it is simple and available for most types of defect. Primary closure may be considered as the simplest method if the defective area is <16 cm2. Intraoperative indocyanine green angiography can help avoid secondary flap revisions. Our protocol ensures a short surgery time, little bleeding, and a low complication rate.
Comparison of clinical, laboratory, and radiological characteristics between SARS-CoV-2 infection and community-acquired pneumonia caused by influenza virus
Authors: Lin Yi-Hua , Luo Wen , Wu Ding-Hui , Lu Fang , Hu Su-Xian , Yao Xiang-Yang , Wang Zhan-Xiang , Shi Yong-Hong 
Published: October 2020

Abstract
Coronavirus disease 2019 (COVID-19) is the most important global public health issue that we currently face. We aimed to explore the clinical features of patients with COVID-19 and compared them with those of hospitalized community-acquired pneumonia (CAP) patients caused by influenza virus during the same period.
From Jan 1, to Mar 4, 2020, patients with COVID-19 or CAP caused by influenza virus who were admitted to the First Affiliated Hospital of Xiamen University were consecutively screened for enrollment.
A total of 35 COVID-19 patients and 22 CAP patients caused by influenza virus were included in this study. Most of COVID-19 patients had characteristics of familial clustering (63%), however, in the other group, there was no similar finding. The percentages of patients with a high fever (the highest recorded temperature was ≥39.0°C; 11% vs 45% [COVID-19 vs CAP groups, respectively]), dyspnea (9% vs 59%), leukocytosis (3% vs 32%), elevated C-reactive protein concentrations (>10 mg/L, 48% vs 86%), elevated procalcitonin levels (>0.1 ng/ml, 15% vs 73%), PaO2/FiO2 <200 mm Hg (4% vs 22%), and infiltration on imaging (29% vs 68%) in the COVID-19 group were less than those same indices in the hospitalized CAP patients caused by influenza virus. Ground-glass opacity with reticular pattern (63%) and interlobular septal thickening (71%) in chest CT were commonly observed in the COVID-19 group.
COVID-19 and CAP caused by influenza virus appear to share some similarities in clinical manifestaions but they definitely have major distinctions. Influenza infection remains a health problem even during COVID-19 pandemic.
Heat Shock Factor 1 in Relation to Tumor Angiogenesis and Disease Progression in Patients With Pancreatic Cancer
Authors: Lin Qiuman , Xiao Gui , Wang Guiliang , He Qingzhang , Xu Linfang , Qiu Ping , Tan Sipin , Gong Min , Wen Jianbo , Xiao Xianzhong 
Published: October 2020

Objective
In this article, the aims were to study the expression of heat shock factor 1 (HSF1) in patients with pancreatic cancer and to elucidate the relevance between HSF1, angiogenesis, clinicopathological factors, and prognosis.

Methods
Pancreatic cancer, paracancerous, and normal pancreatic tissues were collected. The HSF1 RNA and protein expressions were identified using quantitative real-time reverse transcription polymerase chain reaction and immunohistochemical staining. Associations of HSF1 and cluster of differentiation 34 with clinical variables and disease outcomes were investigated.

Results
Compared with the normal pancreatic and paracancerous tissue, HSF1 RNA and protein significantly showed higher expression in the pancreatic cancer tissue and was significantly associated with microvessel density. The high expression of HSF1 did not correspond to the patients' sex, age, carcinoembryonic antigen level, diameter of tumors, and locations; however, it corresponded significantly with carbohydrate antigen 19-9 level, lymph node metastasis, tumor node metastasis stage, differentiation degree, vascular invasion, and distant metastasis. The expression levels of HSF1 and cluster of differentiation 34 were significantly correlated with prognosis, disease specificity, and survival. The high expression of HSF1 would lead to worse prognosis and decrease in survival time and disease-free survival time.

Conclusions
HSF1 expression level in pancreatic cancer tissue could be an ideal prognostic biomarker for risk stratification and a potential therapeutic target for patients with pancreatic cancer.
Prevalence of Acute Rehabilitation for Kids in the PICU: A Canadian Multicenter Point Prevalence Study*
Authors: Choong Karen , Zorko David J. , Awojoodu Ronke , Ducharme-Crevier Laurence , Fontela Patricia S. , Lee Laurie A. , Guerguerian Anne-Marie , Garcia Guerra Gonzalo , Krmpotic Kristina , McKelvie Brianna , Menon Kusum , Murthy Srinivas , Sehgal Anupam , Weiss Matthew J. , Kudchadkar Sapna R. 
Published: October 2020

Objectives:
To evaluate mobilization practices, barriers, and mobility-related adverse events in Canadian PICUs.

Design:
National 2-day point prevalence study.

Setting:
Thirteen PICUs across Canada.

Patients:
Children with a minimum 72-hour PICU length of stay on the allocated study day.

Interventions:
None.

Measurements and Main Results:
Outcomes of interest were the prevalence and nature of mobilization activities, rehabilitation resources, adverse events, and factors associated with out-of-bed mobility and therapist-provided mobility. Two PICUs (15%) had early mobilization practice guidelines, and one PICU (8%) reported a formal process for engaging families in the mobilization of patients. The prevalence of mobilization was 110 of 137 patient-days (80%). The commonest activity was out-of-bed mobility (87/137; 64% patient-days); there was no active mobilization on 46 patient-days (34%). Therapists provided mobility on 33% of patient-days. Mobility was most commonly facilitated by nurses (74% events) and family (49% events). Family participation was strongly associated with out-of-bed mobility (odds ratio 6.4; p = 0.001). Intubated, mechanically ventilated patients were mobilized out-of-bed on 18 of 50 patient-days (36%). However, the presence of an endotracheal tube, vasoactive infusions, and age greater than or equal to 3 years were independently associated with not being mobilized out-of-bed. Barriers were reported on 58 of 137 patient-days (42%), and adverse events occurred in 22 of 387 mobility events (6%).

Conclusions:
Mobilization is common and safe, and the majority of children in Canadian PICUs are being mobilized out-of-bed, even when mechanically ventilated. Family engagement in PICU-based rehabilitation is increasing. This study provides encouraging evidence that common barriers can be overcome in order to safely mobilize children in PICUs.
At-Home Breathing Exercise for the Elderly Using a Party Horn
Authors: Takahata Hideaki 
Published: October 2020

Objective:
To test the efficacy of at-home breathing exercises for the elderly using a party horn.

Methods:
Maximum phonation time, swallowing speed, and maximum voluntary tongue pressure were recorded before and after the 6-month exercise period in 53 medically stable elderly subjects.

Results:
Maximum phonation time, swallowing speed, and maximum voluntary tongue pressure significantly improved in 26 (49.0%) participants who continued the exercise throughout the study period, while swallowing speed significantly decreased in those who did not continue the exercise (n = 21).

Conclusion:
Blowing into a party horn is feasible for the elderly and may maintain their respiration and swallowing.
Features of C-reactive protein in COVID-19 patients within various period: a cohort study
Authors: Huang Guoxin , Qu Gaojing , Yu Hui , Zhang Meiling , Song Xiaoming , Chen Lei , Zhu Haoming , Wang Yunfu , Pei Bin 
Published: October 2020

ABSTRACTBACKGROUNDCoronavirus disease 2019 (COVID-19) has been declared as a threat to the global. Due to the lack of efficient treatments, indicators were urgently needed during the evolvement of disease to analyze the illness and prognosis and prevent the aggravation of COVID-19.METHODSAll laboratory confirmed COVID-19 patients hospitalized in Xiangyang No.1 People’s Hospital were included. Patients’ general information, clinical type, CRP value and outcome were collected. CRP values of all patients during disease course from different initial time were analyzed.RESULTSThe 131 enrolled patients were 50.13±17.13 years old. All cases underwent 724 tests of CRP since symptom onset, 53.18% of the test results were abnormal and the median value was 9.52(2.63-34.10) mg/L. The first median value on the day 8 from exposure onset was 39.08(11.92-47.89) mg/L then fluctuated around it until the day 28. The CRP median increased from 15.93 mg/L to 41.44 mg/L and then decreased to 18.26 mg/L before transformation of severe type, and then increased to 62.25 mg/L on the transforming date. Conversely, the CRP median increased from 56.17 mg/L 102.75 mg/L before transformation of critical type but decreased to 68.68 mg/L on the transforming date. The changes of CRP median over time before death ranged from 77.77 mg/L to 133.52 mg/L.CONCLUSIONSCRP increased before symptom onset and substantially increased during the early-to-mid stage (especially early stage), which was different from other virus-infected diseases. The changes of CRP before the transformation of clinical type was inconsistent with the aggravating of illness. And the CRP maintained over 100.00 mg/L prompted poor prognosis.
Ultrastructural view of astrocyte-astrocyte and astrocyte-synapse contacts within the hippocampus
Authors: Kiyoshi Conrad M. , Aten Sydney , Arzola Emily P. , Patterson Jeremy A. , Taylor Anne T. , Du Yixing , Guiher Ally M. , Philip Merna , Camacho Elizabeth Gerviacio , Mediratta Devin , Collins Kelsey , Benson Emily , Kidd Grahame , Terman David , Zhou Min 
Published: October 2020

SummaryAstrocytes branch out and make contact at their interfaces. However, the ultrastructural interactions of astrocytes and astrocytes with their surroundings, including the spatial-location selectivity of astrocyte-synapse contacts, remain unknown. Here, the branching architecture of three neighboring astrocytes, their contact interfaces, and their surrounding neurites and synapses have been traced and 3D reconstructed using serial block-face scanning electron microscopy (SBF-SEM). Our reconstructions reveal extensive reflexive, loop-like processes that serve as scaffolds to neurites and give rise to spongiform astrocytic morphology. At the astrocyte-astrocyte interface, a cluster of process-process contacts were identified, which biophysically explains the existence of low inter-astrocytic electrical resistance. Additionally, we found that synapses uniformly made contact with the entire astrocyte, from soma to terminal processes, and can be ensheathed by two neighboring astrocytes. Lastly, in contrast to densely packed vesicles at the synaptic boutons, vesicle-like structures were scant within astrocytes. Together, these ultrastructural details should expand our understanding of functional astrocyte-astrocyte and astrocyte-neuron interactions.
The importance of knowledge and trust for ethical fashion consumption
Authors: Liu Yongdan , Liu Matthew Tingchi , Pérez Andrea , Chan Wilco , Collado Jesús , Mo Ziying 
Published: October 2020

PurposeThe clothing industry is one of the most polluting industries in the world, although manufacturers and retailers are trying to revert this tendency by applying ethical fashion principles. Drawing on the knowledge–attitude–behavior (KAB) model or practice, this study aims to predict Chinese consumers' purchase intention of ethical fashion by employing and extending the theory of planned behavior (TPB).Design/methodology/approachThe extended TPB model incorporates knowledge of ethical fashion and trust in the fashion industry and two critical variables in ethical fashion literature to explain the purchase intention of ethical fashion. Primary data from 245 Chinese respondents were collected in 2019. The model was tested and analyzed through structural equation modeling (SEM).FindingsResults show that the extended TPB model has higher predictability than the original TPB model. Attitude toward ethical fashion and subjective norm significantly predicts purchase intention while perceived behavioral control (PBC) does not. In addition, trust of ethical fashion is positively related to attitude toward ethical fashion and purchase intention, whereas knowledge of ethical fashion plays a significant role in predicting trust and the three TPB factors. The subjective norm was found to have the most significant impact on consumers' intention to purchase ethical fashion, which shows that social pressure from one individual's reference group is the most dominant factor in forming consumer's purchase intention on ethical fashion.Originality/valueThe findings enrich the past literature on ethical fashion that trusting belief is a salient determinant of consumers' attitude toward ethical fashion and purchase intention of ethical fashion products. The findings also supported the applicability of KAB and TPB in the domain of ethical consumption in the context of a developing country.
Municipal collaborative planning boosting climate resilience in the built environment
Authors: Flyen Cecilie , Hauge Åshild Lappegard , Almås Anders-Johan , Godbolt Åsne Lund 
Published: October 2020

Purpose
A meta-study covering the past decade maps the development of Norwegian municipal planning, climate adaptation and institutional vulnerability towards climate change. This paper aims to explore the implementation of climate adaptive changes in Norwegian legal planning and building framework into municipal practice and policy instruments from 2007 to 2016. The study is planned to answer the question: what drivers ensure increased municipal efforts in their climate adaptive planning and building practice?

Design/methodology/approach
The paper presents empirical findings from two qualitative research projects, each with nine interviews of municipal key personnel within three municipalities’ planning and building services and an ongoing qualitative, expert interview-based study (eight individual/group interviews).

Findings
Risk reduction and climate resilience are still unsatisfactorily attended in many Norwegian municipalities. There is a gap between political and administrative levels in communicating bilateral expectations and needs for incorporation of climate adaptive measures. Policy instruments maintaining climate adaptation are in demand by different building process actors. Yet, extreme weather events seem to be the main drivers for actual implementation of climate change aspects into municipal policy instruments. Networking, both within and between municipalities, is an important strategy for learning climate adaptation.

Research limitations/implications
Both globally and in Norway, the focus on climate change impacts is steadily increasing. Municipal risk and vulnerability analyses are statutory, as is the incorporation of the results into local plans at appropriate levels.

Originality/value
The originality of this paper is the meta-perspective over the past decade, the qualitative approach and the use of environmental psychology theories.
Customers' experience of purchasing event tickets: mining online reviews based on topic modeling and sentiment analysis
Authors: Celuch Krzysztof 
Published: October 2020

PurposeIn search of creating an extraordinary experience for customers, services have gone beyond the means of a transaction between buyers and sellers. In the event industry, where purchasing tickets online is a common procedure, it remains unclear as to how to enhance the multifaceted experience. This study aims at offering a snapshot into the most valued aspects for consumers and to uncover consumers' feelings toward their experience of purchasing event tickets on third-party ticketing platforms.Design/methodology/approachThis is a cross-disciplinary study that applies knowledge from both data science and services marketing. Under the guise of natural language processing, latent Dirichlet allocation topic modeling and sentiment analysis were used to interpret the embedded meanings based on online reviews.FindingsThe findings conceptualized ten dimensions valued by eventgoers, including technical issues, value of core product and service, word-of-mouth, trustworthiness, professionalism and knowledgeability, customer support, information transparency, additional fee, prior experience and after-sales service. Among these aspects, consumers rated the value of the core product and service to be the most positive experience, whereas the additional fee was considered the least positive one.Originality/valueDrawing from the intersection of natural language processing and the status quo of the event industry, this study offers a better understanding of eventgoers' experiences in the case of purchasing online event tickets. It also provides a hands-on guide for marketers to stage memorable experiences in the era of digitalization.