bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Social Support on Colorectal Cancer Screening among Adult Hispanics/Latinos: A Randomized Community-based Study in Central Pennsylvania
Authors: Dominic Oralia G. , Chinchilli Vern , Wasserman Emily , Curry William J. , Kambic Daniel M. , Caicedo Christian H. , Ramirez Amelie G. , Ochoa John A. , Lengerich Eugene J. 
Published: March 2020

Abstract
In the United States, the five-year survival rate of colorectal cancer for Latinos is lower than it is for White, non-Latinos. Differences in survival are due, in part, to Latinos being diagnosed at a later stage. An ethnic gap in the use of colorectal cancer screening contributes to the difference in survival. We developed, implemented, and evaluated a targeted colorectal cancer screening intervention to increase colorectal cancer screening uptake by sex, ethnicity, and geography. We measured actual colorectal cancer screening uptake in both arms as a method to determine completion rates. We used a randomized, community-based, participatory design to test the impact of social support (intervention) on completion of a provider-recommended, take-home fecal immunochemical test (FIT) kit screening test among average-risk, urban, and rural Pennsylvania Latino adults age 50 and older not currently adherent to national colorectal cancer screening guidelines (n = 264). Participants in each arm attended a community-based educational program offered at eight sites. Among the 264 participants, 154 (58%) returned a completed usable FIT kit screening test. A higher return rate was observed among participants in the social support arm (66.0%) compared with the control (47.2%). Participants in the social support arm were statistically significant 2.67 times as likely to return a completed FIT kit. Of these, 27 (17.5%) had a positive FIT kit screening test result. The results of this study suggest that social support is an effective method to increase colorectal cancer screening rates among Latinos. Future studies should examine dissemination and implementation of community-based strategies among Latinos that include social support.
Speech Recognition Using MFCC and VQLBG
Authors: Suman M. , Harish K. , Kumar K. Manoj , Samrajyam S. 
Published: March 2020

<p>Speaker Recognition is the computing task of confirmatory a user’s claimed identity mistreatment characteristics extracted from their voices. This technique is one of the most helpful and in style biometric recognition techniques in the world particularly connected to areas in that security could be a major concern. It are often used for authentication, police work, rhetorical speaker recognition and variety of connected activities. The method of Speaker recognition consists of two modules particularly feature extraction and have matching. Feature extraction is that the method during which we have a tendency to extract a tiny low quantity of knowledge from the voice signal that will later be used to represent every speaker. Feature matching involves identification of the unknown speaker by scrutiny the extracted options from his/her voice input with those from a collection of identified speakers. Our projected work consists of truncating a recorded voice signal, framing it, passing it through a window perform, conniving the Short Term FFT, extracting its options and Matching it with a hold on guide. Cepstral constant Calculation and Mel frequency Cepstral Coefficients (MFCC) area unit applied for feature extraction purpose.VQLBG (Vector Quantization via Linde-Buzo-Gray) algorithmic rule is used for generating guide and feature matching purpose.</p>
Experimental and Modeling Dynamic Study of the Indirect Solar Water Heater: Application to Rabat Morocco
Authors: Badr Ouhammou , Frimane Azeddine , Mohammed Aggour , Daouchi Brahim , Bah Abdellah , Kazdaba Halima 
Published: March 2020

The Indirect Solar Water Heater System (SWHS) with Forced Circulation is modeled by proposing a theoretical dynamic multi-node model. The SWHS, which works with a 1,91 m<sup>2</sup> PFC and 300 L storage tank, and it is equipped with available forced circulation scale system fitted with an automated sub-system that controlled hot water, is what the experimental setup consisted of. The system, which 100% heated water by only using solar energy. The experimental weather conditions are measured every one minute. The experiments validation steps were performed for two periods, the first one concern the cloudy days in December, the second for the sunny days in May; the average deviations between the predicted and the experimental values is 2 %, 5 % for the water temperature output and for the useful energy are 4 %, 9 % respectively for the both typical days, which is very satisfied. The thermal efficiency was determined experimentally and theoretically and shown to agree well with the EN12975 standard for the flow rate between 0,02 kg/s and 0,2kg/s.
The PCORnet Blood Pressure Control Laboratory
Authors: Pletcher Mark J. , Fontil Valy , Carton Thomas , Shaw Kathryn M. , Smith Myra , Choi Sujung , Todd Jonathan , Chamberlain Alanna M. , O’Brien Emily C. , Faulkner Madelaine , Maeztu Carlos , Wozniak Gregory , Rakotz Michael , Shay Christina M. , Cooper-DeHoff Rhonda M. 
Published: March 2020

Background:
Uncontrolled blood pressure (BP) is a leading preventable cause of death that remains common in the US population despite the availability of effective medications. New technology and program innovation has high potential to improve BP but may be expensive and burdensome for patients, clinicians, health systems, and payers and may not produce desired results or reduce existing disparities in BP control.

Methods and Results:
The PCORnet Blood Pressure Control Laboratory is a platform designed to enable national surveillance and facilitate quality improvement and comparative effectiveness research. The platform uses PCORnet, the National Patient-Centered Clinical Research Network, for engagement of health systems and collection of electronic health record data, and the Eureka Research Platform for eConsent and collection of patient-reported outcomes and mHealth data from wearable devices and smartphones. Three demonstration projects are underway: BP track will conduct national surveillance of BP control and related clinical processes by measuring theory-derived pragmatic BP control metrics using electronic health record data, with a focus on tracking disparities over time; BP MAP will conduct a cluster-randomized trial comparing effectiveness of 2 versions of a BP control quality improvement program; BP Home will conduct an individual patient-level randomized trial comparing effectiveness of smartphone-linked versus standard home BP monitoring. Thus far, BP Track has collected electronic health record data from over 826 000 eligible patients with hypertension who completed ≈3.1 million ambulatory visits. Preliminary results demonstrate substantial room for improvement in BP control (<140/90 mm Hg), which was 58% overall, and in the clinical processes relevant for BP control. For example, only 12% of patients with hypertension with a high BP measurement during an ambulatory visit received an order for a new antihypertensive medication.

Conclusions:
The PCORnet Blood Pressure Control Laboratory is designed to be a reusable platform for efficient surveillance and comparative effectiveness research; results from demonstration projects are forthcoming.
Remediation Procedures for Improving Educator Performance
Authors: Bischoff Robert W. 
Published: March 2020

The Administration of the Utah School for the Blind is of the opinion that this comprehensive Evaluation, Remediation, and Probation Procedure will be effective in improving educator performance. If it is not successful in improving educator performance, it does establish the documented evidence necessary for termination. It does provide the opportunity and evidence for the administration's, fellow educators’, and the professional association's desire to offer substantial help to an educator who has been evaluated as performing unsatisfactorily. In most cases where remediation has been used by school districts, educators have improved their performance as a result of the procedure. In some cases where educators have not improved their performance they have recognized that sufficient documented evidence existed for their termination. Most have resigned, but a few have necessitated termination. Where necessary, the Remediation Procedure assisted the termination action in a very supportive manner. Anyone desiring further information about these procedures please contact the Utah School for the Blind, 742 Harrison Blvd., Ogden, UT 84404.
Analysis of the Genetic Characteristics of a Chinese Family With Otosclerosis
Authors: Zhang Yongli , Tang Qi , Xue Ruoyan , Zhu Xiaohui , Yang Hua , Gao Zhiqiang 
Published: March 2020

Background: Otosclerosis is a focal lesion of the inner ear. The role of genetic factors in the pathogenesis of otosclerosis has received increasing attention. We analyzed the clinical manifestations, inheritance pattern, and pathogenic genes in a family with otosclerosis. Methods: We collected clinical data and generated a family pedigree. High-throughput second-generation sequencing technology was used to identify candidate genes by performing whole-exome sequencing of 7 members of the family, and Sanger sequencing was performed to validate candidate gene mutations in the 7 family members. Results: Otosclerosis was characterized by autosomal dominant inheritance in this family. Whole-exome sequencing did not reveal mutation sites in known deafness-related genes. However, a c.2209A > G (p.T737A) mutation was detected in exon 6 of the SP1 gene, which is associated with the COL1A1 gene. This mutation was a pathogenic mutation, and Sanger sequencing confirmed that this mutation cosegregated with the clinical phenotype among the family members. Conclusions: The pattern of otosclerosis in this family is consistent with autosomal dominant inheritance, and the SP1 gene, harboring the c.2209A > G (p.T737A) mutation in exon 6, may be the causative gene of otosclerosis in this family.
The use of extracorporeal membrane oxygenation in human immunodeficiency virus–positive patients: a review of a multicenter database
Authors: Brogan Thomas V , Thiagarajan Ravi R , Lorusso Roberto , McMullan D Michael , Di Nardo Matteo , Ogino Mark T , Dalton Heidi J , Burke Christopher R , Capatos Gerry 
Published: March 2020

Aim: We chose to evaluate the survival of extracorporeal membrane oxygenation among patients with human immunodeficiency virus in a multicenter registry. Methods: Retrospective case review of the Extracorporeal Life Support Organization Registry respiratory failure of all patients with human immunodeficiency virus supported with extracorporeal membrane oxygenation. Results: A total of 126 patients were included. Survival to discharge was 36%. Eight infants were supported with extracorporeal membrane oxygenation and three (37.5%) survived to discharge. Respiratory extracorporeal membrane oxygenation was the primary indication (78%) with a 39% survival, while cardiac and extracorporeal cardiopulmonary resuscitation indications accounted for 16% and 6% of patients with survivals of 30% and 12.5%, respectively. These differences did not reach significance. There were no significant differences between survivors and non-survivors in demographic data, but non-survivors had significantly more non–human immunodeficiency virus pre–extracorporeal membrane oxygenation infections than survivors. There were no differences in other pre–extracorporeal membrane oxygenation supportive therapies, mechanical ventilator settings, or arterial blood gas results between survivors and non-survivors. The median duration of mechanical ventilation prior to cannulation was 52 (interquartile range: 13-140) hours, while the median duration of the extracorporeal membrane oxygenation exposure was 237 (interquartile range: 125-622) hours. Ventilator settings were significantly lower after 24 hours compared to pre–extracorporeal membrane oxygenation settings. Complications during extracorporeal membrane oxygenation exposure including receipt of renal replacement therapy, inotropic infusions, and cardiopulmonary resuscitation were more common among non-survivors compared to survivors. Central nervous system complications were rare. Conclusion: Survival among patients with human immunodeficiency virus infection who receive extracorporeal membrane oxygenation was less than 40%. Infections before extracorporeal membrane oxygenation cannulation occurred more often in non-survivors. The receipt of renal replacement therapy, inotropic infusions, or cardiopulmonary resuscitation during extracorporeal membrane oxygenation was associated with worse outcome.
How do patients pass through stroke services? Identifying stroke care pathways using national audit data
Authors: Gittins Matthew , Lugo-Palacios David G , Paley Lizz , Bray Benjamin , Bowen Audrey , Vail Andy , Gannon Brenda , Tyson Sarah 
Published: March 2020

Objective: To map and describe how patients pass through stroke services. Methods: Data from 94,905 stroke patients (July 2013–July 2015) who were still inpatients 72 hours after hospital admission were extracted from a national stroke register and were used to identify the routes patients took through hospital and community stroke services. We sought to categorize these routes through iterative consultations with clinical experts and to describe patient characteristics, therapy provision, outcomes and costs within each category. Results: We identified 874 routes defined by the type of admitting stroke team and subsequent transfer history. We consolidated these into nine distinct routes and further summarized these into three overlapping ‘pathways’ that accounted for 99% of the patients. These were direct discharge (44%), community rehabilitation (47%) and inpatient transfer (19%) with 12% of the patients receiving both inpatient transfer and community rehabilitation. Patients with the mildest and most severe strokes were more likely to follow the direct discharge pathway. Those perceived to need most therapy were more likely to follow the inpatient transfer pathway. Costs were lowest and mortality was highest for patients on the direct discharge pathway. Outcomes were best for patients on the community rehabilitation pathway and costs were highest where patients underwent inpatient transfers. Conclusion: Three overarching stroke care pathways were identified which differ according to patient characteristics, therapy needs and outcomes. This pathway mapping provides a benchmark to develop and plan clinical services, and for future research.
Routine use proportion and determining factors of the Canadian Occupational Performance Measure in the real-world setting: A retrospective cross-sectional study in Japan
Authors: Sawada Tatsunori , Tomori Kounosuke , Kimori Yumi , Kato Moe , Wakabayashi Minori , Ohno Kanta , Seike Yosuke , Saito Yuki 
Published: March 2020

Introduction The aim of this retrospective cross-sectional study is to examine the routine use proportion and factors determining the use of the Canadian Occupational Performance Measure in the real-world subacute rehabilitation setting. Methods This study retrospectively collected data from all inpatients and occupational therapists at a single Japanese subacute rehabilitation ward during 2017, including Functional Independence Measure motor/cognitive scores, years of experience, and rate of Canadian Occupational Performance Measure administration (that is, Canadian Occupational Performance Measure proportion). Multiple logistic regression analyses were used to identify the determining factors of daily routine Canadian Occupational Performance Measure use/non-use, after which cut-off values were calculated. Results Of the 619 included clients, the Canadian Occupational Performance Measure was applied in 232 cases (37%). A multiple logistic regression analysis revealed two significant determining factors of its use: Canadian Occupational Performance Measure proportion (odds ratio, 1.06) and Functional Independence Measure cognitive item (odds ratio, 1.22). The cut-off value, sensitivity, and specificity, respectively, were 35.4%, 0.73, and 0.36 ( p < 0.0001) for the Canadian Occupational Performance Measure proportion and 25.5, 0.84, and 0.45 ( p < 0.0001) for the Functional Independence Measure cognitive score. Conclusion The client’s high-level cognitive skill and occupational therapist’s attitude may determine the use of the Canadian Occupational Performance Measure.
A review of mobile applications to enhance coaching in occupational therapy
Authors: Setoguchi Miranda , Motruk Sylvia , Frank Veronica , Kessler Dorothy 
Published: March 2020

Introduction The use of mobile applications (apps) in healthcare is increasing. Apps can promote access to services and support health behaviour change. Apps may be useful to support coaching in occupational therapy; however, information to support the selection of these apps is lacking. The primary objective of this study was to evaluate apps for the potential use of augmenting coaching in occupational therapy. Methods Apps were identified through systematic searches in iTunes and Google Play stores. The identified apps were evaluated against pre-determined usability criteria. Results Following screening and evaluation, 36 apps were identified as meeting the established criteria and therefore being potentially clinically useful. From these, 14 were chosen to discuss in depth based on their clinical utility and overall features. Conclusions The apps highlighted may be useful in occupational therapy coaching practice. The evaluation criteria used provide a framework to consider app usability; however, validation is needed.
Acute treatment patterns in patients with migraine newly initiating a triptan
Authors: Lipton Richard B , Marcus Steven C , Shewale Anand R , Dodick David W , Viswanathan Hema N , Doshi Jalpa A 
Published: March 2020

BackgroundTriptans are the most commonly used acute treatment for migraine. This study evaluated real-world treatment patterns following an initial triptan prescription to understand refill rates and use of non-triptan medications for the acute treatment of migraine.MethodsCommercially-insured adult patients over 18 years of age with a triptan prescription between 1/1/2013 to 31/12/2013 were identified from the Optum Clinformatics™ Data Mart database, with date of the first triptan fill designated as index date. Inclusion was limited to those with no fills for a triptan in the 12 months prior to index date (i.e. new users or initiators of triptans) and continuous enrollment in the 12 months pre- and 24 months post-index date. Fills for index triptan, non-index triptan, and other acute treatments for migraine were assessed for up to 24 months post-index.ResultsAmong 10,509 patients, 50.8% did not refill the initial triptan within 12 months and 43.6% did not refill within 24 months. In the 12 months post-index, 90.5% of patients used only one type of triptan, 8.4% used two different triptans, and 1.0% used three or more triptans. Among patients with and without a triptan refill, use of opioids (39% vs. 42%), non-steroidal anti-inflammatory drugs (22% vs. 22%), and butalbital-containing products (9% vs. 10%) were similar.ConclusionMore than half of those who newly initiated a triptan did not refill their initial prescription, and less than 1 in 10 used two or more triptans within 12 months. High rates of non-triptan acute medication use were found over 12 and 24 months of follow-up, most commonly opioids.
The effect of epigallocatechin-3-gallate on morphine-induced memory impairments in rat: EGCG effects on morphine neurotoxicity
Authors: Saffar S , Fatemi I , Rahmani M , Hassanshahi J , Sahamsizadeh A , Allahtavakoli M , Sheibani V , Kaeidi A 
Published: March 2020

Aim of study: This investigation evaluated the capacity of epigallocatechin-3-gallate (EGCG) as the main polyphenolic compound in the green tea extract against memory impairment and neurotoxicity in morphine-treated rats. Methods: To measure the EGCG effect (5 and 50 mg/kg, i.p., co-treated with morphine) on spatial learning and memory of morphine-administrated male Wistar rats (45 mg/kg, s.c., 4 weeks), the Morris water maze test was used. Some apoptotic protein levels (Bax, Bcl-2, and cleaved caspase 3) were evaluated in the hippocampus tissue by the Western blot test. Also, oxidative stress status (malondialdehyde level, glutathione peroxidase, and superoxide dismutase activity) was measured in hippocampus tissue. Results: The data presented that EGCG treatment (50 mg/kg) inhibited the morphine-induced memory deficits in rats. Also, EGCG administration reduced the apoptosis and oxidative stress in the hippocampus of morphine-treated rats. Conclusions: Our data indicate that EGCG can improve memory in morphine-treated rats. Molecular mechanisms underlying the detected effects could be related to the prevention of apoptosis and oxidative stress in the hippocampus of morphine-treated rats.
Parent moral distress in serious pediatric illness: A dimensional analysis
Authors: Mooney-Doyle Kim , Ulrich Connie M 
Published: March 2020

Background: Moral distress is an important and well-studied phenomenon among nurses and other healthcare providers, yet the conceptualization of parental moral distress remains unclear. Objective: The objective of this dimensional analysis was to describe the nature of family moral distress in serious pediatric illness. Design and methods: A dimensional analysis of articles retrieved from a librarian-assisted systematic review of Scopus, CINAHL, and PsychInfo was conducted, focusing on how children, parents, other family members, and healthcare providers describe parental moral distress, both explicitly through writings on parental moral experience and implicitly through writings on parental involvement in distressing aspects of the child’s serious illness. Ethical considerations: To promote child and family best interest and minimize harm, a nuanced understanding of the moral, existential, emotional, and spiritual impact of serious pediatric illness is needed. The cases used in this dimensional analysis come from the first author’s IRB approved study at the Children’s Hospital of Philadelphia and subsequent published studies; or have been adapted from the literature and the authors’ clinical experiences. Findings: Three dimensions emerged from the literature surrounding parent moral distress: an intrapersonal dimension, an interpersonal dimension, and a spiritual/existential dimension. The overarching theme is that parents experience relational solace and distress because of the impact of their child’s illness on relationships with themselves, their children, family, healthcare providers, their surrounding communities, and society. Discussion: Elucidating this concept can help nurses and other professionals understand, mitigate, or eliminate antecedents to parental moral distress. We discuss how this model can facilitate future empirical and conceptual bioethics research, as well as inform the manner in which healthcare providers engage, collaborate with, and care for families during serious pediatric illness. Conclusion: Parent moral distress is an important and complex phenomenon that requires further theoretical and empirical investigation. We provide an integrated definition and dimensional schematic model that may serve as a starting point for future research and dialogue.