bluuebunny/crossref_metadata_2025_split huggingface dataset:
A competitive analysis of port of Hong Kong: from external to internal
Authors: Liu Zihua , Yang Dong , Ng Y. N. Eppie 
Published: March 2020

AbstractThis paper aims to analyse the competitive equilibrium of Hong Kong international port after the cooperation among terminal operators. To achieve our research objective, a comprehensive analysis framework is proposed. We assume that the port services provided by Shenzhen and Hong Kong have heterogeneity, thus apply Cournot price competition model to understand the external competition. We find that the heterogeneity level can affect the demand of Hong Kong international port. For different heterogeneity levels, different competitive equilibriums among terminal operators of Hong Kong are discussed. We further apply Edgeworth model and Stackelberg Leadership Model to describe the internal competition of Hong Kong international port. Based on analysis, some recommendations are provided to the terminal operators of Hong Kong.
Rhabdomyosarcoma with an intratumoral adult type rhabdomyoma nodule with focal neuronal differentiation - diagnosis, prognosis and treatment of a rare disease
Authors: Santana Suelen Cunha , Prado Filip Messias Santana , de Oliveira Leal Marcos Lima , Athanazio Paulo , Athanazio Daniel Abensur 
Published: March 2020

AbstractRhabdomyosarcomas with areas reminiscent of adult type rhabdomyoma are rare and almost exclusive of pretreated tumors. We present a case of 17-year-old patient who sought medical assistance due to a right painless paratesticular mass. At gross examination, the paratesticular mass was a 5 cm tumor (embryonal rhabdomyosarcoma) with a discrete 2.0 cm grayish nodule at the periphery. At microscopy, smaller nodule showed large eosinophilic granular cells suggestive of adult type rhabdomyoma. These cells were strongly and diffusely positive for desmin and multifocally positive for myogenin. Focal neuronal and neural differentiations (NSE and GFAP expression) were also detected. Awareness of benign appearing intratumoral rhabdomyoma in rhabdomyosarcomas of paratestis/retroperitonium is of relevance. Such tumor heterogeneity may be a diagnostic pitfall especially in the scenario of needle biopsies and frozen section consultation.
Association between miR-196a2 polymorphism and the development of hepatocellular carcinoma in the Egyptian population
Authors: Gawish Eman Ahmed , Abu-Raia Gamal Yousef , Osheba Iman , Sabry Aliaa , Allam Esraa 
Published: March 2020

Abstract
Background
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers worldwide. Circulating microRNAs (miRNAs) are endogenous, small (17–25 nucleotides) non-coding RNAs that are overexpressed in many human cancers including HCC. Single-nucleotide polymorphisms (SNPs) of miRNAs play an important role in the pathogenesis of HCC. In our study, we aimed to evaluate the role of miR-196a2 rs11614913 polymorphism in the development of HCC. A total of 200 subjects, including 80 HCC patients, 60 patients with liver cirrhosis, and 60 healthy controls were selected. The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was taken to determine miR-196a2 rs11614913 polymorphism.

Results
The genotype distribution of the TC and CC, TC + CC genotypes, and the C allele were significantly higher in HCC patients than control and cirrhotic groups (P = 0.02, P = 0.005, and P = 0.003, respectively). Compared with the wild-type TT genotype, both the variant TC, CC, TC + CC genotypes were associated with an elevated risk of HCC (OR = 2.77, 95% CI = 1.27–6.04), (OR = 4.94, 95% CI = 1.74–14.07), (OR = 3.24, 95% CI = 1.55–6.78) respectively. Moreover, the C allele was correlated with an increased risk of HCC (OR = 2.30, 95% CI = 1.40–3.76) compared to the wide-type T allele. Also, there is no significant correlation between the different miR-196a2 genotypes and either the clinico-pathologic features of HCC or its aggressiveness.

Conclusion
Our results suggest that the miR-196a2 rs11614913 polymorphism is associated with an increased risk of HCC in the Egyptian population.
Short-term High-fat Overfeeding Does Not Induce NF-κB Inflammatory Signaling in Subcutaneous White Adipose Tissue
Authors: Dewhurst-Trigg Rebecca , Wadley Alex J , Woods Rachel M , Sherar Lauren B , Bishop Nicolette C , Hulston Carl J , Markey Oonagh 
Published: March 2020

Abstract

Context
It is unclear how white adipose tissue (WAT) inflammatory signaling proteins respond during the early stages of overnutrition.

Objective
To investigate the effect of short-term, high-fat overfeeding on fasting abdominal subcutaneous WAT total content and phosphorylation of proteins involved in nuclear factor-κB (NF-κB) inflammatory signaling, systemic metabolic and inflammatory biomarkers.

Design
Individuals consumed a high-fat (65% total energy from total fat), high-energy (50% above estimated energy requirements) diet for 7 days.

Results
Fifteen participants (aged 27 ± 1 years; body mass index 24.4 ± 0.6 kg/m2) completed the study. Body mass increased following high-fat overfeeding (+1.2 ± 0.2 kg; P &lt; 0.0001). However, total content and phosphorylation of proteins involved in NF-κB inflammatory signaling were unchanged following the intervention. Fasting serum glucose (+0.2 ± 0.0 mmol/L), total cholesterol (+0.4 ± 0.1 mmol/L), low-density lipoprotein cholesterol (+0.3 ± 0.1 mmol/L), high-density lipoprotein cholesterol (+0.2 ± 0.0 mmol/L), and lipopolysaccharide-binding protein (LBP; +4.7 ± 2.1 µg/mL) increased, whereas triacylglycerol concentrations (−0.2 ± 0.1 mmol/L) decreased following overfeeding (all P &lt; 0.05). Systemic biomarkers (insulin, soluble cluster of differentiation 14 [CD14], C-reactive protein, interleukin-6, tumor necrosis factor-α and monocyte chemoattractant protein-1) and the proportion and concentration of circulating CD14+ monocytes were unaffected by overfeeding.

Conclusion
Acute lipid oversupply did not impact on total content or phosphorylation of proteins involved in WAT NF-κB inflammatory signaling, despite modest weight gain and metabolic alterations. Systemic LBP, which is implicated in the progression of low-grade inflammation during the development of obesity, increased in response to a 7-day high-fat overfeeding period.
One-year test-retest reliability of ten vision tests in Canadian athletes
Authors: Aloosh Mehdi , Leclerc Suzanne , Long Stephanie , Zhong Guowei , Brophy James M. , Schuster Tibor , Steele Russell , Shrier Ian 
Published: March 2020

Background: Vision tests are increasingly being suggested for use in concussion management and baseline testing. Concussions, however, often occur months after baseline testing and reliability studies generally examine intervals limited to days or one week. Therefore, our objective was to determine the one-year test-retest reliability of these tests. Methods: We assessed one-year test-retest reliability of ten vision tests in elite Canadian athletes followed by the Institut National du Sport du Quebec. We included athletes who completed two baseline (preseason) annual evaluations by one clinician within 365±30 days. We excluded athletes with any concussion or vision training in between the annual evaluations or presented with any factor that is believed to affect the tests (e.g. migraines, etc.). Data were collected from clinical charts. We evaluated test-retest reliability using Intraclass Correlation Coefficient (ICC) and 95% limits of agreement (LoA). Results: We examined nine female and seven male athletes with a mean age of 22.7 (SD 4.5) years. Among the vision tests, we observed excellent test-retest reliability in Positive Fusional Vergence at 30cm (ICC=0.93) but this dropped to 0.55 when an outlier was excluded in a sensitivity analysis. There was good to moderate reliability in Negative Fusional Vergence at 30cm (ICC=0.78), Phoria at 30cm (ICC=0.68), Near Point of Convergence break (ICC=0.65) and Saccade (ICC=0.56). The ICC for Positive Fusional Vergence at 3m (ICC=0.56) also decreased to 0.21 after removing one outlier. We found poor reliability in Near Point of Convergence (ICC=0.47), Gross Stereoscopic Acuity (ICC=0.03) and Negative Fusional Vergence at 3m (ICC=0.0). ICC for Phoria at 3m was not appropriate because scores were identical in 14/16 athletes. 95% LoA of the majority of tests were ±40% to ±90%. Conclusions: Four tests had moderate one-year test-retest reliability. The remaining tests had poor reliability. The tests would therefore be useful only if concussion has a moderate-large effect on scores.
the philosophical baby and socratic orality
Authors: Consentino Antonio 
Published: March 2020

Lipman’s curriculum of “Philosophy for Children” was the outcome of a harmonious and fruitful partnership between philosophy and pedagogy, but over the time practice shows the risk of a double fall and reduction: on the one side into the ditch of pedagese and, on the other, into the ditch of philosofese. Using the expression “Philosophical Practice of Community” (PPC) instead of “Philosophy for children” (P4C) appears preferable to protect the latter from the risk of being considered, because of its evocative vagueness, both a sort of toy-philosophy, and a kind of pedagogical device suitable for all purposes. Set out in terms of PPC, the project of doing philosophy with children becomes part of a broader field of research concerning each of the three components (“philosophical”, “practice”, and “community”) and their relationships. If ideas are not clear about what “philosophical” means, the risk is that philosophy can be assimilated to other approaches and used as general as empty label. Among the many questions that a PPC puts on the table, I’ll try to frame three of them: 1) Is it necessary to know the philosophical tradition to practice philosophy with children? 2) Who are the philosophers? 3) How to revitalize the Socratic orality?
The interobserver reliability of the diagnosis and classification of scaphoid fractures using high-resolution peripheral quantitative CT
Authors: Daniels Anne M. , Wyers Caroline E. , Janzing Heinrich M. J. , Sassen Sander , Loeffen Daan , Kaarsemaker Sjoerd , van Rietbergen Bert , Hannemann Pascal F. W. , Poeze Martijn , van den Bergh Joop P. 
Published: March 2020

AimsBesides conventional radiographs, the use of MRI, CT, and bone scintigraphy is frequent in the diagnosis of a fracture of the scaphoid. However, which techniques give the best results remain unknown. The investigation of a new imaging technique initially requires an analysis of its precision. The primary aim of this study was to investigate the interobserver agreement of high-resolution peripheral quantitative CT (HR-pQCT) in the diagnosis of a scaphoid fracture. A secondary aim was to investigate the interobserver agreement for the presence of other fractures and for the classification of scaphoid fracture.MethodsTwo radiologists and two orthopaedic trauma surgeons evaluated HR-pQCT scans of 31 patients with a clinically-suspected scaphoid fracture. The observers were asked to determine the presence of a scaphoid or other fracture and to classify the scaphoid fracture based on the Herbert classification system. Fleiss kappa statistics were used to calculate the interobserver agreement for the diagnosis of a fracture. Intraclass correlation coefficients (ICCs) were used to assess the agreement for the classification of scaphoid fracture.ResultsA total of nine (29%) scaphoid fractures and 12 (39%) other fractures were diagnosed in 20 patients (65%) using HR-pQCT across the four observers. The interobserver agreement was 91% for the identification of a scaphoid fracture (95% confidence interval (CI) 0.76 to 1.00) and 80% for other fractures (95% CI 0.72 to 0.87). The mean ICC for the classification of a scaphoid fracture in the seven patients diagnosed with scaphoid fracture by all four observers was 73% (95% CI 0.42 to 0.94).ConclusionWe conclude that the diagnosis of scaphoid and other fractures is reliable when using HR-pQCT in patients with a clinically-suspected fracture. Cite this article: Bone Joint J 2020;102-B(4):478–484.
Acetabular revision using a dual mobility cup as treatment for dislocation in Charnley total hip arthroplasty
Authors: Hoggett Lee , Cross Charlotte , Helm Anthony 
Published: March 2020

Aims Dislocation remains a significant complication after total hip arthroplasty (THA), being the third leading indication for revision. We present a series of acetabular revision using a dual mobility cup (DMC) and compare this with our previous series using the posterior lip augmentation device (PLAD). Methods A retrospective review of patients treated with either a DMC or PLAD for dislocation in patients with a Charnley THA was performed. They were identified using electronic patient records (EPR). EPR data and radiographs were evaluated to determine operating time, length of stay, and the incidence of complications and recurrent dislocation postoperatively. Results A total of 28 patients underwent revision using a DMC for dislocation following Charnley THA between 2013 and 2017. The rate of recurrent dislocation and overall complications were compared with those of a previous series of 54 patients who underwent revision for dislocation using a PLAD, between 2007 and 2013. There was no statistically significant difference in the mean distribution of sex or age between the groups. The mean operating time was 71 mins (45 to 113) for DMCs and 43 mins (21 to 84) for PLADs (p = 0.001). There were no redislocations or revisions in the DMC group at a mean follow-up of 55 months (21 to 76), compared with our previous series of PLAD which had a redislocation rate of 16% (n = 9) and an overall revision rate of 25% (n = 14, p = 0.001) at a mean follow-up of 86 months (45 to 128). Conclusion These results indicate that DMC outperforms PLAD as a treatment for dislocation in patients with a Charnley THA. This should therefore be the preferred form of treatment for these patients despite a slightly longer operating time. Work is currently ongoing to review outcomes of DMC over a longer follow-up period. PLAD should be used with caution in this patient group with preference given to acetabular revision to DMC. Cite this article: Bone Joint J 2020;102-B(4):423–425.
Molecular identification of amylase-producing thermophilic bacteria isolated from Bukit Gadang Hot Spring, West Sumatra, Indonesia
Authors: Ardhi Aulia , Nadenggan Sidauruk Arina , Suraya Nabella , Wahyu Pratiwi Nova , Pato Usman , Saryono  
Published: March 2020

Abstract. Ardhi A, Sidauruk AN, Suraya N, Pratiwi NW, Pato U, Saryono. 2020. Molecular identification of amylase-producing thermophilic bacteria isolated from Bukit Gadang Hot Spring, West Sumatra, Indonesia. Biodiversitas 21: 994-1000. Amylase is one of the hydrolytic enzymes that is widely used in a wide number of industrial processes such as food, fermentation, textile, paper, detergent, and pharmaceutical industries. Amylase produced by thermophilic bacteria may be thermostable, which is very beneficial in several applications requiring high temperature, for example, the process of gelatinization, liquefaction, and saccharification are performed in high temperature involved in the starch processing. In this study, the amylase-producing ability of thermophilic bacteria isolated from Bukit Gadang hot spring, West Sumatra, Indonesia, was checked and followed by molecular identification. Thirteen isolates that were successfully isolated from the hot springs were microscopically and macroscopically characterized, biochemically tested, and determined their amylase enzyme activity both qualitatively and quantitatively. The isolate that performed the best amylase activity was identified using the molecular technique. The DNA sequencing was carried out in 16S rRNA and continued with BLAST search for species identification. The result of molecular identification showed that the isolate with the best amylase activity was identified as Bacillus licheniformis. The optimum amylase production (231.33 U/ml) and the best enzyme-specific activity (101.79 U/mg) were obtained at the incubation time of 36 hours.
The diversity of leaves and asiaticoside content on three accessions of Centella asiatica with the addition of chicken manure fertilizer
Authors: Maratul Happy , YULI WIDYASTUTI  , SUPRIYONO  , Yunus Ahmad 
Published: March 2020

Abstract. Mumtazah HM, Supriyono, Widyastuti Y, Yunus A. 2020. The diversity of leaves and asiaticoside content on three accessions of Centella asiatica with the addition of chicken manure fertilizer. Biodiversitas 21: 1035-1040. Centella asiatica (L.) commonly known as an essential medicinal herb. This plant has high diversity, especially in leaf morphology. The main objective of this research was to determine the morphology of leaves and the effect of chicken manure dosage on the increase of asiaticoside content. The leaves of three accessions characterized, and then C. asiatica planted. The research design used a completely randomized design (CRD) factorial, with the first factor is accession (C) with 3 levels (C1: accession 1, C2: accession 2, C3: accession 3). The second factor was chicken manure with 4 levels dosage (P1: 0 ton ha-1, P2: 10 tons ha-1, P3: 15 tons ha-1 and P4: 20 tons ha-1). Asiaticoside analysis used the TLC method with chloroform: methanol: water (65:25:4) as mobile phase. The result from this research showed that the diversity in leaf morphology of three accessions is in leaf size and petiole length. Accession 3 has the widest leaf size (7.3 cm) and the longest petiole (9.8 cm), accession 2 with a leaf width of 5.8 cm and petiole length in 8.5 cm, while the accession 1 has the least leaf width (5.3 cm) and the length of the petiole is the shortest with 7.3 cm. Observation results of asiaticoside showed that the highest content of asiaticoside produced by accession 3 (0.19%), then accession 1 with a content of 0.15%, while accession 2 showed the lowest asiaticoside content (0.13%). The treatment of chicken manure addition significantly increase asiaticoside content in accessions 1 and 3, but in accession 2 it was not significantly increased. The highest content of asiaticoside (0.34%) were in accession 3 with the addition of chicken manure 20 tons ha-1 (P4).
Another proof of the persistence of Serre symmetry in the Frölicher spectral sequence
Authors: Milivojević Aleksandar 
Published: March 2020

AbstractSerre’s duality theorem implies a symmetry between the Hodge numbers, hp,q = hn−p,n−q, on a compact complex n–manifold. Equivalently, the first page of the associated Frölicher spectral sequence satisfies \dim E_1^{p,q} = \dim E_1^{n - p,n - q} for all p, q. Adapting an argument of Chern, Hirzebruch, and Serre [3] in an obvious way, in this short note we observe that this “Serre symmetry” \dim E_k^{p,q} = \dim E_k^{n - p,n - q} holds on all subsequent pages of the spectral sequence as well. The argument shows that an analogous statement holds for the Frölicher spectral sequence of an almost complex structure on a nilpotent real Lie group as considered by Cirici and Wilson in [4].
Parity funding of health care contributions in Germany: A DSGE perspective
Authors: Enders Almira , Groll Dominik , Stähler Nikolai 
Published: March 2020

AbstractGermany reintroduced parity funding of the statutory health insurance scheme in January 2019 by lowering the contribution rates for employees and raising those for employers, leaving the total rate constant. This reduces the tax wedge between total labour costs and net wages. After a small demand impulse on impact, followed by a small downturn in the first two years after implementation, an estimated New Keynesian DSGE model indicates small positive long-run output and employment effects. However, the reduced tax wedge leads to lower public revenues. Aggregate macroeconomic and welfare effects will depend on how the government compensates for these revenue losses.
Effect of deformation temperature on mechanical properties and microstructure of TWIP steel for expansion tube
Authors: Haitao Xue , Dengke Wang , Kaihong Song 
Published: March 2020

AbstractAccording to the downhole temperature filed, the mechanical behavior of TWIP steel for expansion tube was studied in the temperature range from 25°C to 300°C. Meanwhile, the phase and microstructure changes before and after deformation were investigated by X-ray diffractometer (XRD), optical microscope (OM), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The results indicate that yield strength, tensile strength and elongation decrease with temperature increasing. The TWIP steel is single-phase of austenite before and after deformation. Analysis on the microstructure shows that the deformation twins gradually decrease with increasing temperature. The deformation process cannot benefit from the deformation twins, which is responsible for the decreased ductility. In addition, due to the increased temperature, the stacking fault energy becomes high enough to restrain twinning, thus dislocation glide becomes the main deformation mechanism.
Interspecific variability of 1,8-cineole content, phenolics and bioactivity among nine Eucalyptus taxa growing under the sub-humid bioclimate stage
Authors: Chograni Hnia , Riahi Leila , Dhahri Samir , Ezzine Olfa , Chakroun Hanen , Messaoud Chokri 
Published: March 2020

Abstract

Background

Eucalyptus essential oils and extracts are used since the ancient times in alternative medicine. The 1,8-cineole is the most significant constituent of Eucalyptus essential oil, while phenolic contents define the value of eucalyptus extracts. Based on the last considerations, interspecific variability of 1,8-cineole content, phenolics and antioxidant potentials among nine Eucalyptus taxa growing under the sub-humid bioclimate stage of Tunisia was investigated.

Methods
Essential oil profiling was assessed based on gas chromatography-mass spectrometry analysis. Total phenolic and flavonoid contents were assessed using Folin–Ciocalteau and aluminium chloride colorimetric methods, respectively. The antioxidant ability of Eucalyptus volatile metabolites and extracts was achieved based on two test systems namely DPPH and FRAP assays.

Results
Qualitative and quantitative variations in the composition of essential oils according to the studied taxon were shown. The total phenolic and flavonoid contents varied also significantly among the investigated samples. Based on the obtained results, the species Eucalyptus sideroxylon exhibits the highest 1,8-cineole content (76.24 ± 0.86), total phenolics and flavonoids contents (38.5 ± 1.4 mg GAE /g DW and 18.6 ± 0.3 mg RE /g DW, respectively). Moreover this species highlighted the highest free radical-scavenging ability and ferric reducing power for both essential oil and methanolic extracts. Chemometric multivariate analysis showed the classification of the nine studied taxa to three clusters.

Conclusions
The pattern of 1,8-cineole concentration, phenolic and flavonoid contents for the studied nine Eucalyptus species and hybrid showed E. sideroxylon species as the potential candidate for further improvement strategies regarding the production of eucalyptus essential oils and phenolics with high quality for pharmaceutical industry.
A logarithmic estimate for the inverse source scattering problem with attenuation in a two-layered medium
Authors: Entekhabi Mozhgan N. , Gunaratne Ajith 
Published: March 2020

Abstract
The paper aims a logarithmic stability estimate for the inverse source problem of the one-dimensional Helmholtz equation with attenuation factor in a two layer medium. We establish a stability by using multiple frequencies at the two end points of the domain which contains the compact support of the source functions.