bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of psychiatric illness on oral tissue, gingival and periodontal health among non-institutionalized psychiatric patients of Mangalore, India
Authors: Nayak Sangeeta , Pai Keshava , Shenoy Ramya 
Published: June 2020

Aim of the studyPsychiatric illness makes overall health weaker. Different types of Psychiatric illness causes various oral changes. The research aimed at assessing the oral health parameters among non-institutionalized psychiatric patients of private set up.Subject or material and methodsIn this cross-sectional study 250 psychiatric patients were examined. The parameters related to psychiatric illness were documented using their medical records. A questionnaire including demographic details, oral hygiene practices, habits, occupation, and income was used. A t full mouth examination was carried out to assess oral changes, oral dryness , plaque, gingival and periodontal status.ResultsThe age of the participants ranged from 21 - 70 years with a mean age of 36 years.The majority of participants were suffering from psychiatric illness like depression, schizophrenia, mood disorders and mania respectively. Majority of the participants suffering from psychiatric illness were homemakers. This study showed a link between low income population to psychiatric illness. The participants also reported oral dryness which may be partly due to psychiatric medications. Gingival and plaque index scores showed statistically significant association to presence of psychiatric illness.DiscussionThe present study reported different oral conditions in the psychiatric patients. The3-4 decade were affected age groupConclusionsSubjects with psychiatric illness were having poor oral health. Dental examination should be incorporated as a part general examination. Policymakers need to consider optimal methods of intervention for mental disorders among low-income individuals. This group of patients who are making major part of the population of the society should be attended with utmost care.
Developing clinical leadership in New Zealand hospice staff nurses
Authors: Simmons Scott W , Jacobs Stephen , McKillop Ann 
Published: June 2020

Background:Staff nurse clinical leadership is a relatively new concept that includes the elements of collaboration, coordination, patient advocacy, and often quite autonomous decision-making required of palliative care nurses. Staff nurses need structural and psychological empowerment to develop as clinical leaders.Aims:The aim of this study was to establish baseline data regarding the self-perceived structural and psychological empowerment experienced by New Zealand hospice staff nurses and their ability to practise as clinical leaders.Methods:An explanatory sequential mixed-methods design was used, which included questionnaires measuring structural and psychological empowerment and clinical leadership behaviours and focus group discussions.Findings:Survey respondents reported that they were moderately psychologically and sometimes or rarely structurally empowered and felt that they can practise as clinical leaders most of the time. Two themes were identified from the focus groups.Conclusion:New Zealand staff hospice nurses felt that—despite feeling only moderately psychologically empowered, and only sometimes or rarely structurally empowered—they practise as clinical leaders most of the time.
Raman mediated ultrafast all-optical NOR gate
Authors: Datta Tanmoy , Sen Mrinal 
Published: June 2020

A new device architecture has been proposed in this paper implementing the all-optical cascadable logic NOR functionality. The device functions based on stimulated Raman scattering (SRS) in silicon nanocrystal embedded slotted photonic crystal waveguide (SPCW). Substantial miniaturizations both in operating power and overall footprint of the device have been achieved owing to the ultrahigh SRS gain of silicon nanocrystal and strong spatio-temporal confinement of the SPCW. Successful operation of the device has been demonstrated at a pulse rate that is as high as 125 Gbps.
1-D imaging of rotation-vibration non-equilibrium from pure rotational ultrafast coherent anti-Stokes Raman scattering
Authors: Chen Timothy Y. , Goldberg Benjamin M. , Patterson Brian D. , Kolemen Egemen , Ju Yiguang , Kliewer Christopher J. 
Published: June 2020

We present one-dimensional (1-D) imaging of rotation-vibration
non-equilibrium measured by two-beam pure rotational hybrid
femtosecond/picosecond coherent anti-Stokes Raman scattering (fs/ps
CARS). Simultaneous measurements of the spatial distribution of
molecular rotation-vibration non-equilibrium are critical for
understanding molecular energy transfer in low temperature plasmas and
hypersonic flows. However, non-equilibrium CARS thermometry until now
was limited to point measurements. The red shift of rotational energy
levels by vibrational excitation was used to determine the rotational
and vibrational temperatures from 1-D images of the pure rotational
spectrum. Vibrational temperatures up to 5500 K were detected in a

C
H

4

/

N

2

nanosecond-pulsed pin-to-pin plasma
within 2 mm near the cathode. This approach enables study of
non-equilibrium systems with 40 µm spatial resolution.
Etiologies of neonatal cholestasis at a tertiary hospital in Bangladesh
Authors: Benzamin Md. , Khadga Mukesh , Begum Fahmida , Rukunuzzaman Md. , Mazumder Md. Wahiduzzaman , Lamia Khan Nahid , Islam Md. Saidul , Rahman AZM Raihanur , Karim ASM Bazlul 
Published: June 2020

Background Neonatal cholestasis is an important etiology of chronic liver disease in young children. It has a varied etiology. There is considerable delay in presentation and diagnosis of neonatal cholestasis in Bangladesh. Lack of awareness and knowledge among the pediatricians regarding etiological diagnosis and outcome of neonatal cholestasis is the reasons for poor outcome in major portion of cases in Bangladesh.
Objective To evaluate the etiological spectrum of neonatal cholestasis.
Methods This retrospective study was conducted at the Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. We reviewed medical records of children who were diagnosed with neonatal cholestasis. Complete diagnostic profiles of every cases with age of presentation, male-female ratio and final diagnosis were analyzed.
Results A total of 114 children with neonatal cholestasis were evaluated. Subjects’ male-female ratio was 1.92: 1.0, and mean age at hospitalization was 92.7 (SD 39.5) days. Biliary atresia was the most common etiology (47.4%), followed by idiopathic neonatal hepatitis/INH (21.9%). Other identified etiologies were, toxoplasmosis, others (syphilis, varicella-zoster, parvovirus b19), rubella, cytomegalovirus (CMV), and herpes/TORCH infection (8.61%), progressive familial intrahepatic cholestasis/PFIC (4.4%), galactosemia (4.4%), choledochal cyst (3.5%), sepsis (1.8%), urinary tract infection/UTI (1.8%), hypothyroidism (1.8%), lipid storage disease/Niemann-Pick disease (0.9%), non-syndromic paucity of interlobular bile ducts (2.67%), and Caroli’s disease (0.9%).
Conclusion In Bangladesh, neonatal cholestasis cases are most often due to obstructive causes, particularly biliary atresia. Idiopathic (INH), infectious (primarily TORCH), metabolic, and endocrine causes followed in terms of frequency.
Fecal calprotectin and its association with functional dyspepsia in children
Authors: Manoppo Jeanette , Somali Rizal , ASPR PITIKA 
Published: June 2020

Background Calprotectin is a calcium-binding protein found normally in small amounts within the digestive tract. Fecal calprotectin measurement is used as a biomarker to identify digestive tract inflammation. Functional dyspepsia is one of the most common health issues in children, occurring in 3-27%, and accounts for considerable quality of life impairment and health care expenses.
Objective To determine fecal calprotectin concentration in generally healthy children as well as to assess for a possible association between fecal calprotectin and functional dyspepsia.
Methods This cross-sectional study was conducted from February to April 2019 in primary school-aged children in Manado, North Sulawesi. Subjects consisted of 38 children aged 6–12 years. Fecal calprotectin was measured in subjects’ stool specimens, and considered to be normal if fecal calprotectin concentration of < 50 μg/g. Diagnosis of functional dyspepsia was defined using the parent-filled Rome IV questionnaire form. Data were analyzed with Chi-square and Phi-coefficient correlation tests.
Results Thirty-eight subjects, 22 boys and 16 girls, were grouped according to fecal calprotectin concentration (normal vs. elevated) and functional dyspepsia diagnosis. Mean fecal calprotectin concentration was 312.45 μg/g in the functional dyspepsia group and 20.89 μg/g in the healthy group. Elevated fecal calprotectin was found in 55.6% of the functional dyspepsia group and 10.3% of the healthy group. There was a positive correlation between fecal calprotectin elevation and functional dyspepsia (r=0.471; P=0.004).
Conclusion Current fecal calprotectin physiological cut-off level of 50 μg/g seems valid for children aged 6–12 years. Elevated fecal calprotectin is associated with functional dyspepsia in children.
Effects of probiotic on gut microbiota in children with acute diarrhea: a pilot study
Authors: Samsudin Dion Darius , Firmansyah Agus , Hidayati Eka Laksmi , Yuniar Irene , Karyanti Mulya Rahma , Roeslani Rosalina Dewi 
Published: June 2020

Background Acute diarrhea is a common health problem in Indonesia. During acute diarrhea, changes in gut microbiota are marked by decrease beneficial microbes Bifidobacterium and Lactobacillus, and increased pathogenic bacteria Enterobacter and Clostridium. Such microbial imbalances are known as dysbiosis. Treatment with probiotics may help repair dysbiosis, quicken healing time, and decrease complications.
Objective To assess for dysbiosis during acute diarrhea, and determine if it can be normalized by probiotic treatment.
Methods This placebo-controlled, unblinded clinical trial was performed in Budhi Asih District Hospital, Jakarta, from January to March 2018. Twenty-four children age 6-24 months with acute diarrhea and 12 healthy children were enrolled. First fecal specimen was collected for all subjects and analyzed using non-culture real time PCR to count the population of Lactobacillus, Bifidobacterium, Enterobacter, Clostridium, and all bacteria. Children with diarrhea were assigned to probiotic or placebo treatment for 5 days and the second fecal specimen was analyzed two weeks after the diarrhea subsided.
Results Prior to treatment, significant higher amounts of Lactobacillus were observed in children with acute diarrhea than in healthy controls [median (interquartile range/IR): 1.52x103 (1.22x104) vs. 6.87x10 (2.41x102), respectively; proportion in percentage (from total bacteria population): 0.044% vs. 0.003%, respectively]. However, median (IR) Clostridium was significantly higher in healthy controls than in children with acute diarrhea [2.37x102 (4.64x103) vs. 4.67 (1.50x102), respectively (P<0.05), with proportion of 0.01% vs. 0.0001%, respectively]. Children who received probiotics had significantly higher count of Bifidobacterium compared to the placebo group [1.94x104 (4.97x104) vs. 1.74x103 (2.08x107), respectively, with proportion of 0.394% vs. 0.081%, respectively].
Conclusion This pilot study do not find evidence of dysbiosis in children with acute diarrhea. Group who received probiotic had higher Bifidobacterium count compared towards those who received placebo.
Preventive therapy of antioxidant vitamins against the blood choline levels in cardiovascular patients
Authors: Ali Muhammad Asif , Nasir Muhammad , Pasha Talat Naseer , Javid Imran , Muzaffar Rizwana , Rashid Anjum , Ur Rehman Habib , Gondal Tanweer Aslam , Imran Muhammad , Sharifi-Rad Javad , Iqbal Zafar , Ahmed Sheraz 
Published: June 2020

Therapeutic role of antioxidant against lipid profile and lipoprotein (choline) was observed by the different researchers, but clinical evidences required about the use of antioxidant vitamins against the lipoproteins. Patients with clinical evidence of cardiovascular disease (CVD) confirmed by standard diagnostic techniques were followed. Newly or recently, diagnosed case subjects were recruited wherever possible. At least 120 cases, subjects both male and female with CVD were selected from a local hospital. Four groups developed on the base of antioxidant therapy and blood samples were collected at zero day, 20 days, 40 days and 60 days. vitamins C and E are the major dietary cellular and lipid antioxidants, respectively; we found no evidence to support the use of vitamin or antioxidant supplements in the reduction of mortality. However, they are helpful in the management of prevention of cardiovascular disease.
Sex Differences in Maturation and Attrition of Adult Neurogenesis in the Hippocampus
Authors: Yagi Shunya , Splinter Jared E.J. , Tai Daria , Wong Sarah , Wen Yanhua , Galea Liisa A.M. 
Published: June 2020

AbstractSex differences exist in the regulation of adult neurogenesis in the hippocampus in response to hormones and cognitive training. Here, we investigated the trajectory and maturation rate of adult-born neurons in the dentate gyrus (DG) of male and female rats. Sprague Dawley rats were perfused 2 h, 24 h, one week (1w), 2w, or 3w after bromodeoxyuridine (BrdU) injection, a DNA synthesis marker that labels dividing progenitor cells and their progeny. Adult-born neurons (BrdU/NeuN-ir) matured faster in males compared with females. Males had a greater density of neural stem cells (Sox2-ir) in the dorsal, but not in the ventral, DG and had higher levels of cell proliferation (Ki67-ir) than non-proestrous females. However, males showed a greater reduction in neurogenesis between 1week and 2weeks after mitosis, whereas females showed similar levels of neurogenesis throughout the weeks. The faster maturation and greater attrition of new neurons in males compared with females suggests greater potential for neurogenesis to respond to external stimuli in males and emphasizes the importance of studying sex on adult hippocampal neurogenesis.
Digital Literacy in Formal Online Education: A Short Review
Authors: Yustika Gaung Perwira , Iswati Sri 
Published: June 2020

This study aims to explain the current findings of digital literacy in formal online education. The methods of research is a type of library descriptionÂ obtained from relevant scientific articles obtained from internet search media library engines: proquest, researchgate, google scholar and other search engines with keyword search "digital literacy" to find the publication of related scientific papers / relevant to the topic. Then the 41 articles found (listed in the references) are studied and then explained from the author's perspective. Digital literacy is multi-dimensional, built by multi construct hypotesis. In the previous research found a higher level of digital literacy that was positively related to the output of learning outcomes in the subjects studied. Online learnersÂ feel anxious because they do not understand and are accustomed to online classes, especially for those who have limited computer skills. Most importantly, independent students get the final grade of the program far better than non-independent students. The best predictor of academic success, measured by the final grades, namely components of academic skills, reading and writing abilities. Higher levels of digital literacy positively affected the high output of learning outcomes to student academic performance.
TEMEL KAYNAKLAR VE ÇEKİCİLİKLER YÖNÜNDEN KASTAMONU İLİ REKABETÇİLİĞİNİN KONAKLAMA SEKTÖRÜ PAYDAŞLARI BAKIŞ AÇISINDAN DEĞERLENDİRİLMESİ
Authors: AKKUŞ Gülizar , BÖYÜKYILMAZ Savaş 
Published: June 2020

Turizm destinasyonlarının sahip olduğu temel kaynak ve çekicilikler, özellikle yakın rakiplerine kıyasla destinasyonlara üstünlük sağlamaktadır. Bu sebeple birçok destinasyon öncelikli olarak bu kaynak ve çekiciliklerini tespit etmeye odaklanmakta, ardından rekabetçilik ölçümleri yapmaktadır. Ancak kapsamlı literatür taraması sonucu destinasyon rekabetçiliğine ilişkin araştırmaların sıklıkla yabancı yazında yer aldığı, Türkçe yazında ise konuya ilişkin araştırma sayısı oldukça kısıtlı olmakla birlikte yalnızca büyük şehirlere odaklanıldığı saptanmıştır.
Bu araştırmada hem otantik hem de metropol kuvvetli rakipleri bulunan Kastamonu ilinin sahip olduğu temel kaynaklara ve çekiciliklere yönelik turizm sektörü paydaşlarının görüşlerini değerlendirmek amaçlanmıştır. Paydaşlar içerisinde önemli bir rol oynayan konaklama işletmesi yöneticileri ile toplam 15 derinlemesine görüşme gerçekleştirilmiştir. Görüşme soruları oluşturulurken Ritchie ve Crouch’un (2003) Kavramsal Rekabetçilik Modeli’nde yer alan temel kaynaklar ve çekicilikler faktörünü oluşturan yedi bileşenden faydalanılmıştır. Araştırma sonucunda paydaşların Kastamonu’yu fizyografi ve iklim bileşeni açısından orman kaynakları ve manzara güzelliği, kültür ve tarih bileşeni açısından geleneksel mimari, etkinlikler karması bileşeni açısından yetişkinlere yönelik ve zor maceraya dayalı etkinlikler, özel etkinlikler bileşeni açısından tarihsel kilometre taşlarına yönelik etkinlikler, eğlence bileşeni açısından geleneksel festivaller, üstyapı bileşeni açısından cami, medreseleri ve doğa harikaları, piyasa bağları bileşeni açısından dini ziyaretler ile rakiplerine kıyasla daha rekabetçi bulduğu tespit edilmiştir.
Genomic Analysis of Diverse Members of the Fungal Genus Monosporascus Reveals Novel Lineages, Unique Genome Content and a Potential Bacterial Associate
Authors: Robinson Aaron J , Natvig Donald O , Chain Patrick S G 
Published: June 2020

Abstract
The genus Monosporascus represents an enigmatic group of fungi important in agriculture and widely distributed in natural arid ecosystems. Of the nine described species, two (M. cannonballus and M. eutypoides) are important pathogens on the roots of members of Cucurbitaceae in agricultural settings. The remaining seven species are capable of colonizing roots from a diverse host range without causing obvious disease symptoms. Recent molecular and culture studies have shown that members of the genus are nearly ubiquitous as root endophytes in arid environments of the Southwestern United States. Isolates have been obtained from apparently healthy roots of grasses, shrubs and herbaceous plants located in central New Mexico and other regions of the Southwest. Phylogenetic and genomic analyses reveal substantial diversity in these isolates. The New Mexico isolates include close relatives of M. cannonballus and M. ibericus, as well as isolates that represent previously unrecognized lineages. To explore evolutionary relationships within the genus and gain insights into potential ecological functions, we sequenced and assembled the genomes of three M. cannonballus isolates, one M. ibericus isolate, and six diverse New Mexico isolates. The assembled genomes were significantly larger than what is typical for the Sordariomycetes despite having predicted gene numbers similar to other members of the class. Differences in predicted genome content and organization were observed between endophytic and pathogenic lineages of Monosporascus. Several Monosporascus isolates appear to form associations with members of the bacterial genus Ralstonia (Burkholdariaceae).
HEAT AND pH STABLE PROTEASE PRODUCED BY A BACTERIUM ISOLATED FROM FIELDS WITH HIGH BORON
Authors: YİĞİT ŞAT Esma , YAMAN Belma NURAL , GEDİKLİ Serap , ÇELİK Pınar AYTAR , ÇABUK Ahmet 
Published: June 2020

In this study, production, optimization and characterization of protease produced by a bacterium isolated from Kırka boron mine distinct were performed. The proteolytic activities of isolates were screened based on Anson method. The optimal production conditions for protease were determined by using Central Composite Design. Bacillus sp. DB14 isolate (accession number: KY110868) exhibited the highest activity in terms of protease enzyme (346.15 U/mg) among the other isolates screened. The highest result for protease activity of Bacillus sp. DB14 isolate was obtained as 481.76 U/mg according to experimental set. Optimum pH and temperature of Bacillus sp. DB14 protease were found as 10.5 and 60 °C, respectively. Interestingly, this enzyme could stand stable at the range of 20-50 °C. However, the enzyme activity started to decrease highly after 50 °C. Besides, pH stability of this enzyme was provided between pH 7 and pH 11. Inhibition of protease was observed in solution with 10 mM Ni2+, Fe3+, Hg2+, Cd2+ and B3+. Cu2+ ion was found to enhance enzyme activity.
Bacillus sp. DB14 protease exhibited remarkably stability in the temperature range of 20 °C and 50 °C. Proteolytic activity values obtained at the range of pH 7-11 were stable. These results indicated that the alkaline protease from this isolate might be potential for biotechnological applications.
Seguridad en la intubación de secuencia rápida recomendada en COVID-19: Informe de experiencia
Authors: Franco Andrezza Serpa , Henrique Danielle Mendonça , Almeida Luana Ferreira de , Prado Lilian Moreira do , Gomes Roberta Varzem Schwenck , Silva Roberto Carlos Lyra 
Published: June 2020

Objetivo: Describir la experiencia de la estrategia implementada para reforzar la seguridad durante la administración de medicamentos potencialmente peligrosos recomendados para la intubación de secuencia rápida en pacientes con COVID-19. Materiales y métodos: Estudio descriptivo tipo relato de experiencias con base en los principios del Programa Nacional de Seguridad del Paciente, en los que se describe la adecuación de la bandeja de administración de medicamentos potencialmente peligrosos durante la intubación de secuencia rápida. La bandeja se codifica por colores y por clases terapéuticas de acuerdo con la secuencia de administración de medicamentos. La estrategia se implementó en conjunto con el equipo multidisciplinar de las unidades de cuidados intensivos de un hospital público cardiovascular en Río de Janeiro. Resultados: Las bandejas con código de color se utilizaron en tres ocasiones durante la intubación de secuencia rápida. Con base en esta estrategia, se elaboró una tabla con las características farmacológicas y de cuidado de enfermería de los medicamentos potencialmente peligrosos disponibles en la sala de preparación de medicamentos para consulta. Discusión: El uso seguro de medicamentos hace parte del tercer reto mundial por la seguridad del paciente propuesto por la Organización Mundial de la Salud. Uno de los factores que contribuye a la incidencia de acontecimientos adversos es el uso de medicamentos potencialmente peligrosos. La aplicación de barreras de seguridad es la estrategia planteada en este relato que se hace necesaria para la prevención de eventos adversos. Conclusiones: La adopción del uso de bandejas codificadas por colores constituyó una barrera frente a la ocurrencia de posibles incidentes derivados del uso de medicamentos potencialmente peligrosos durante la intubación de secuencia rápida en pacientes con COVID-19. Como citar este artículo: Franco, Andrezza Serpa; Henrique, Danielle de Mendonça; Almeida, Luana Ferreira; Prado, Lilian Moreira; Gomes, Roberta Varzem Schwenck; Silva, Roberto Carlos Lyra. Segurança na intubação de sequência rápida recomendada no COVID-19: Relato de experiência. Revista Cuidarte. 2020; 11(2): e1260. http://dx.doi.org/10.15649/cuidarte.1260