bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robust and precise identification of the hygro-expansion of single fibers: a full-field fiber topography correlation approach
Authors: Vonk N. H. , Verschuur N. A. M. , Peerlings R. H. J. , Geers M. G. D. , Hoefnagels J. P. M. 
Published: May 2020

AbstractOver the past decades, natural fibers have become an important constituent in multiple engineering- and biomaterials. Their high specific strength, biodegradability, low-cost production, recycle-ability, vast availability and easy processing make them interesting for many applications. However, fiber swelling due to moisture uptake poses a key challenge, as it significantly affects the geometric stability and mechanical properties. To characterize the hygro-mechanical behavior of fibers in detail, a novel micromechanical characterization method is proposed which allows continuous full-field fiber surface displacement measurements during wetting and drying. A single fiber is tested under an optical height microscope inside a climate chamber wherein the relative humidity is changed to capture the fiber swelling behavior. These fiber topographies are, subsequently, analyzed with an advanced Global Digital Height Correlation methodology dedicated to extract the full three-dimensional fiber surface displacement field. The proposed method is validated on four different fibers: flat viscose, trilobal viscose, 3D-printed hydrogel and eucalyptus, each having different challenges regarding their geometrical and hygroscopic properties. It is demonstrated that the proposed method is highly robust in capturing the full-field fiber kinematics. A precision analysis shows that, for eucalyptus, at 90% relative humidity, an absolute surface strain precision in the longitudinal and transverse directions of, respectively, 1.2 × 10-4and 7 × 10-4is achieved, which is significantly better than existing techniques in the literature. The maximum absolute precision in both directions for the other three tested fibers is even better, demonstrating that this method is versatile for precise measurements of the hygro-expansion of a wide range of fibers.Graphic abstract
Nonsingularity and Stationarity Results for Quasi-Variational Inequalities
Authors: Dreves Axel , Sagratella Simone 
Published: May 2020

AbstractThe optimality system of a quasi-variational inequality can be reformulated as a non-smooth equation or a constrained equation with a smooth function. Both reformulations can be exploited by algorithms, and their convergence to solutions usually relies on the nonsingularity of the Jacobian, or the fact that the merit function has no nonoptimal stationary points. We prove new sufficient conditions for the absence of nonoptimal constrained or unconstrained stationary points that are weaker than some known ones. All these conditions exploit some properties of a certain matrix, but do not require the nonsingularity of the Jacobian. Further, we present new necessary and sufficient conditions for the nonsingularity of the Jacobian that are based on the signs of certain determinants. Additionally, we consider generalized Nash equilibrium problems that are a special class of quasi-variational inequalities. Exploiting their structure, we also prove some new sufficient conditions for stationarity and nonsingularity results.
Career destinations of graduates from a medical school with an 18-week longitudinal integrated clerkship in general practice: a survey of alumni 6 to 8 years after graduation
Authors: Glynn Liam G. , Regan Andrew O. , Casey Monica , Hayes Peter , O’Callaghan Michael , O’Dwyer Patrick , Culhane Aidan , Cuddihy John , Connell Billy O. , Stack Gary , O’Flynn Gerry , O’Donnell Patrick , O’Connor Raymond , McKeague Helena , Grath Deirdre Mc 
Published: May 2020

Abstract
Background
There is a worldwide recruitment and retention crisis in general practice. Workforce planning has identified the need to train more general practitioners as an urgent priority. Exposure of medical students to general practice as part of the formal and hidden curriculum, the use of longitudinal integrated clerkships, and positive experiences and role models in general practice are all thought to be contributing factors to doctors choosing careers in general practice.

Aim
The aim of this study was to identify career destinations of medical school graduates in a medical school with an 18-week longitudinal integrated clerkship in general practice.

Design and setting
This study was conducted in a single graduate entry medical school at the University of Limerick, Ireland.

Participants
Medical school alumni 6–8 years after graduation.

Method
A survey of graduating cohorts of the medical school from 2011 to 2013 was conducted through email and telephone.

Results
There were a total of 175 alumni for the period 2011 to 2013. Data was collected on 92% (161/175) through an online survey, follow-up email and telephone interview, and was triangulated with searches of professional registration databases and information from key informants. Between 6 and 8 years after graduation, a total of 43% of alumni were engaged in general practice as a career.

Conclusion
The reform of the delivery of general practice within medical school curricula should be considered by medical schools, curriculum designers and policy-makers as part of an overall strategy to address the recruitment and retention of general practitioners as part of the global healthcare workforce.
Spatial reasoning skills about 2D representations of 3D geometrical shapes in grades 4 to 9
Authors: Fujita Taro , Kondo Yutaka , Kumakura Hiroyuki , Kunimune Susumu , Jones Keith 
Published: May 2020

AbstractGiven the important role played by students’ spatial reasoning skills, in this paper we analyse how students use these skills to solve problems involving 2D representations of 3D geometrical shapes. Using data from in total 1357 grades 4 to 9 students, we examine how they visualise shapes in the given diagrams and make use of properties of shapes to reason. We found that using either spatial visualisation or property-based spatial analytic reasoning is not enough for the problems that required more than one step of reasoning, but also that these two skills have to be harmonised by domain-specific knowledge in order to overcome the perceptual appearance (or “look”) of the given diagram. We argue that more opportunities might be given to both primary and secondary school students in which they can exercise not only their spatial reasoning skills but also consolidate and use their existing domain-specific knowledge of geometry for productive reasoning in geometry.
An investigation of the ultrasonic joining process parameters effect on the mechanical properties of metal-composite hybrid joints
Authors: Feistauer E. E. , dos Santos J. F. , Amancio-Filho S. T. 
Published: May 2020

AbstractThe ultrasonic joining process was recently introduced as an alternative concept to join through-the-thickness reinforced metal-composite hybrid structures. In this work, the investigation of joining process parameters effect on the joint mechanical performance of Ti-6Al-4V-glass-fiber-reinforced polyetherimide overlap joints was carried out by Box-Behnken design of experiments. The individual and combined effects of joining energy, sonotrode oscillation amplitude, and joining pressure on the ultimate lap shear force were elucidated by response surfaces method and analysis of variance. As a result of this study, a set of optimized joining parameters were obtained to produce joints with high ultimate lap shear force. The obtained reliable reduced model (R2 = 82%) displays a major influence of joining energy (25.3%) and sonotrode oscillation amplitude (21.2%) on the joint mechanical performance. Two-way interaction response surfaces were used to support strategies to optimize the maximum ultimate lap shear force. By comparing the optimized joint condition produced in this work with previously published results an improvement of 79% in ultimate lap shear force was attained, thereby, proving the potential of the proposed process optimization procedure.
Event abstraction in process mining: literature review and taxonomy
Authors: van Zelst Sebastiaan J. , Mannhardt Felix , de Leoni Massimiliano , Koschmider Agnes 
Published: May 2020

AbstractThe execution of processes in companies generates traces of event data, stored in the underlying information system(s), capturing the actual execution of the process. Analyzing event data, i.e., the focus of process mining, yields a detailed understanding of the process, e.g., we are able to discover the control flow of the process and detect compliance and performance issues. Most process mining techniques assume that the event data are of the same and/or appropriate level of granularity. However, in practice, the data are extracted from different systems, e.g., systems for customer relationship management, Enterprise Resource Planning, etc., record the events at different granularity levels. Hence, pre-processing techniques that allow us to abstract event data into the right level of granularity are vital for the successful application of process mining. In this paper, we present a literature study, in which we assess the state-of-the-art in the application of such event abstraction techniques in the field of process mining. The survey is accompanied by a taxonomy of the existing approaches, which we exploit to highlight interesting novel directions.
Mental Disorders in Firefighters Following Large-Scale Disaster
Authors: Wagner Shannon L. , White Nicole , Randall Christine , Regehr Cheryl , White Marc , Alden Lynn E. , Buys Nicholas , Carey Mary G. , Corneil Wayne , Fyfe Trina , Matthews Lynda R. , Fraess-Phillips Alex , Krutop Elyssa 
Published: May 2020

ABSTRACTFirefighting service is known to involve high rates of exposure to potentially traumatic situations, and research on mental health in firefighting populations is of critical importance in understanding the impact of occupational exposure. To date, the literature concerning prevalence of trauma-related mental disorders such as posttraumatic stress disorder (PTSD) has not distinguished between symptomology associated routine duty-related exposure and exposure to large-scale disaster. The present systematic review synthesizes a heterogeneous cross-national literature on large-scale disaster exposure in firefighters and provides support for the hypothesis that the prevalence of PTSD, major depressive disorder, and anxiety disorders are elevated in firefighters compared with rates observed in the general population. In addition, we conducted narrative synthesis concerning several commonly assessed predictive factors for disorder and found that sociodemographic factors appear to bear a weak relationship to mental disorder, while incident-related factors, such as severity and duration of disaster exposure, bear a stronger and more consistent relationship to the development of PTSD and depression in cross-national samples. Future work should expand on these preliminary findings to better understand the impact of disaster exposure in firefighting personnel.
The development and implementation of stewardship initiatives to optimize the prevention and treatment of cytomegalovirus infection in solid-organ transplant recipients
Authors: Jorgenson Margaret R. , Descourouez Jillian L. , Schulz Lucas T. , Goldrosen Kerry A. , Rice John P. , Redfield Robert R. , Saddler Christopher M. , Smith Jeannina A. , Mandelbrot Didier A. 
Published: May 2020

AbstractClassical stewardship efforts have targeted immunocompetent patients; however, appropriate use of antimicrobials in the immunocompromised host has become a target of interest. Cytomegalovirus (CMV) infection is one of the most common and significant complications after solid-organ transplant (SOT). The treatment of CMV requires a dual approach of antiviral drug therapy and reduction of immunosuppression for optimal outcomes. This dual approach to CMV management increases complexity and requires individualization of therapy to balance antiviral efficacy with the risk of allograft rejection. In this review, we focus on the development and implementation of CMV stewardship initiatives, as a component of antimicrobial stewardship in the immunocompromised host, to optimize the management of prevention and treatment of CMV in SOT recipients. These initiatives have the potential not only to improve judicious use of antivirals and prevent resistance but also to improve patient and graft survival given the interconnection between CMV infection and allograft function.
Surface plasma wave in spin-polarized semiconductor quantum plasma
Authors: Kumar Punit , Ahmad Nafees 
Published: May 2020

AbstractThe possibilities of surface plasma wave (SPW) on a metal-vacuum interface in semiconductor quantum plasma by considering the effects of Coulomb exchange (CE) interaction and the spin-polarization has been explored. The dispersion for the SPW has been setup using the modified quantum hydrodynamic (QHD) model taking into account the Fermi pressure, the quantum Bohm force, the CE, and the electron spin. The optical gain of SPW has been evaluated. It is found that CE effects and spin-polarization increases the wave frequency and enhances the gain during the stimulated emission.
Open-Inquiry Course Design in the Public Policy Classroom
Authors: Pennock Andrew 
Published: May 2020

ABSTRACTThis article describes a variant of experiential course design—open inquiry—that has learning-how-to-learn (or metacognition about learning) as a primary course goal. In open-inquiry designs, students first choose the problems that they will study during the course. They then co-create each class period as the semester progresses. They recognize deficiencies in their own content knowledge, skills, and learning processes and take actions to remedy them. By reflecting on their successes and failures, students practice the skill of self-directed learning. This process of metacognitive reflection is a crucial skill that they will need when they face novel problems after graduation. In open-inquiry courses, students have produced high-quality work by learning about substantive policy areas that they choose to study, developing the policy skills that they deem important, and growing in their understanding about how they learn effectively.
The interplay between emotion and modality in the Foreign-Language effect on moral decision making
Authors: Brouwer Susanne 
Published: May 2020

AbstractThis study examined whether theForeign-Language effect, an increase in bilinguals’ rate of rational decisions to moral dilemmas in their foreign versus their native language, is influenced by emotion and the modality in which the dilemmas are presented. 154 Dutch–English bilinguals were asked to read and listen to personal and impersonal moral dilemmas in Dutch or in English. Importantly, the reading task had the character of a self-paced reading task to resemble the listening task as closely as possible. In both modalities, participants’ task was to indicate whether the proposed action was appropriate or not. Results showed that the Foreign-Language effect was present for personal dilemmas only. In addition, an effect of modality demonstrated that participants took overall more rational decisions during the listening than the reading task. These findings give insight in the interplay between language, emotion and task demands, revealing that moral decision making is context-dependent.
The extent and nature of television food advertising to children and adolescents in the Russian Federation
Authors: Kontsevaya AV , Imaeva AE , Balanova YA , Kapustina AV , Breda J , Jewell JM , Salakhov ER , Drapkina OM , Boyland E 
Published: May 2020

AbstractObjective:To assess the frequency, healthfulness and promotional techniques of television food advertising to children and adolescents in the Russian Federation.Design:A cross-sectional study was conducted to monitor food and beverage television advertising. For the five most popular TV channels among children and adolescents, TV broadcasts were recorded for two weekdays and two weekends (320 h) during March–May 2017. Recordings were screened for advertisements. Food advertisements were categorised by food categories and as either ‘permitted’ or ‘not permitted’ for advertising to children in accordance with World Health Organization Regional Office for Europe Nutrient Profile Model (NPM), and promotional techniques in advertisements were recorded.Results:Overall, 11 678 advertisements were coded. Across all channels, food and drink (19·2 %) were the most frequently advertised product type. The most common food categories advertised were beverages (except juices, milk drinks and energy drinks) (24·1 %); yoghurts and other dairy foods (15 %); and chocolate and confectionery (12·3 %). A majority (64·2 %) of food and drink products advertised should not be permitted for advertising to children according to the NPM. The most frequently used persuasive appeals in the food advertisements were low price (15·4 %), product novelty (11·8 %) and enjoyment (10·0 %).Conclusions:Children and adolescents in the Russian Federation are likely exposed to a substantial number of unhealthy food advertisements. There is a need to consider policies to restrict children’s exposure to unhealthy food advertising on television in the Russian Federation.
On the influence of density and morphology on the Urban Heat Island intensity
Authors: Li Yunfei , Schubert Sebastian , Kropp Jürgen P. , Rybski Diego 
Published: May 2020

AbstractThe canopy layer urban heat island (UHI) effect, as manifested by elevated near-surface air temperatures in urban areas, exposes urban dwellers to additional heat stress in many cities, specially during heat waves. We simulate the urban climate of various generated cities under the same weather conditions. For mono-centric cities, we propose a linear combination of logarithmic city area and logarithmic gross building volume, which also captures the influence of building density. By studying various city shapes, we generalise and propose a reduced form to estimate UHI intensities based only on the structure of urban sites, as well as their relative distances. We conclude that in addition to the size, the UHI intensity of a city is directly related to the density and an amplifying effect that urban sites have on each other. Our approach can serve as a UHI rule of thumb for the comparison of urban development scenarios.
Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant lesions
Authors: Feigman Mary J. , Moss Matthew A. , Chen Chen , Cyrill Samantha L. , Ciccone Michael F. , Trousdell Marygrace C. , Yang Shih-Ting , Frey Wesley D. , Wilkinson John E. , dos Santos Camila O. 
Published: May 2020

AbstractPregnancy causes a series of cellular and molecular changes in mammary epithelial cells (MECs) of female adults. In addition, pregnancy can also modify the predisposition of rodent and human MECs to initiate oncogenesis. Here, we investigate how pregnancy reprograms enhancer chromatin in the mammary epithelium of mice and influences the transcriptional output of the oncogenic transcription factor cMYC. We find that pregnancy induces an expansion of the active cis-regulatory landscape of MECs, which influences the activation of pregnancy-related programs during re-exposure to pregnancy hormones in vivo and in vitro. Using inducible cMYC overexpression, we demonstrate that post-pregnancy MECs are resistant to the downstream molecular programs induced by cMYC, a response that blunts carcinoma initiation, but does not perturb the normal pregnancy-induced epigenomic landscape. cMYC overexpression drives post-pregnancy MECs into a senescence-like state, and perturbations of this state increase malignant phenotypic changes. Taken together, our findings provide further insight into the cell-autonomous signals in post-pregnancy MECs that underpin the regulation of gene expression, cellular activation, and resistance to malignant development.
High-throughput transcriptomic and proteomic profiling of mesenchymal-amoeboid transition in 3D collagen
Authors: Čermák Vladimír , Gandalovičová Aneta , Merta Ladislav , Harant Karel , Rösel Daniel , Brábek Jan 
Published: May 2020

AbstractThe plasticity of cancer cell invasion represents substantial hindrance for effective anti-metastatic therapy. To better understand the cancer cells’ plasticity, we performed complex transcriptomic and proteomic profiling of HT1080 fibrosarcoma cells undergoing mesenchymal-amoeboid transition (MAT). As amoeboid migratory phenotype can fully manifest only in 3D conditions, all experiments were performed with 3D collagen-based cultures. Two previously described approaches to induce MAT were used: doxycycline-inducible constitutively active RhoA expression and dasatinib treatment. RNA sequencing was performed with ribo-depleted total RNA. Protein samples were analysed with tandem mass tag (TMT)-based mass spectrometry. The data provide unprecedented insight into transcriptome and proteome changes accompanying MAT in true 3D conditions.
CassavaMap, a fine-resolution disaggregation of cassava production and harvested area in Africa in 2014
Authors: Szyniszewska Anna Maria 
Published: May 2020

AbstractCassava, the third main source of carbohydrates in Africa, provides daily nutrition for over 700 million people on the continent and a vital source of income for subsistence farmers. Despite its importance, our knowledge of the heterogeneity of its distribution in the landscape is limited and outdated. Information on cassava production and harvested area are typically available on aggregated administrative unit level with highly variable temporal range of records, often over a decade old, and represented on a coarse ~10 km by 10 km grid. Here, cassava production and harvested area administrative unit level data for 32 countries are standardised to 2014 FAO reported levels and disaggregated based on the distribution of the rural population in 2014. The grid obtained represents a significant improvement on the previous studies in terms of both spatial resolution (~1 km by 1 km) and temporal accuracy. Enhanced representation of cassava production and harvested area in Africa is an essential resource for policy making as well as designing strategies to manage its main pathogens.
Questing functions and structures of hypothetical proteins from Campylobacter jejuni: a computer-aided approach
Authors: Gazi Md. Amran , Mahmud Sultan , Fahim Shah Mohammad , Islam Md. Rezaul , Das Subhasish , Mahfuz Mustafa , Ahmed Tahmeed 
Published: May 2020

Abstract
Campylobacter jejuni (C. jejuni) is considered to be one of the most frequent causes of bacterial gastroenteritis globally, especially in young children. The genome of C. jejuni contains many proteins with unknown functions termed as hypothetical proteins (HPs). These proteins might have essential biological role to show the full spectrum of this bacterium. Hence, our study aimed to determine the functions of HPs, pertaining to the genome of C. jejuni. An in-silico work flow integrating various tools were performed for functional assignment, three-dimensional structure determination, domain architecture predictors, subcellular localization, physicochemical characterization, and protein–protein interactions (PPIs). Sequences of 267 HPs of C. jejuni were analyzed and successfully attributed the function of 49 HPs with higher confidence. Here, we found proteins with enzymatic activity, transporters, binding and regulatory proteins as well as proteins with biotechnological interest. Assessment of the performance of various tools used in this analysis revealed an accuracy of 95% using receiver operating characteristic (ROC) curve analysis. Functional and structural predictions and the results from ROC analyses provided the validity of in-silico tools used in the present study. The approach used for this analysis leads us to assign the function of unknown proteins and relate them with the functions that have already been described in previous literature.