bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reliability and Change in Erosion Measurements by High-resolution Peripheral Quantitative Computed Tomography in a Longitudinal Dataset of Rheumatoid Arthritis Patients
Authors: Finzel Stephanie , Manske Sarah L. , Barnabe Cheryl C.M. , Burghardt Andrew J. , Marotte Hubert , Scharmga Andrea , Hauge Ellen-Margrethe , Chapurlat Roland , Engelke Klaus , Li Xiaojuan , van Teeffelen Bente C.J. , Conaghan Philip G. , Stok Kathryn S. 
Published: September 2020

Objective.The aim of this multireader exercise was to assess the reliability and change over time of erosion measurements in patients with rheumatoid arthritis (RA) using high-resolution peripheral quantitative computed tomography (HR-pQCT).Methods.HR-pQCT scans of 23 patients with RA were assessed at baseline and 12 months. Four experienced readers examined the dorsal, palmar, radial, and ulnar surfaces of the metacarpal head (MH) and phalangeal base (PB) of the second and third digits, blinded to time order. In total, 368 surfaces (23 patients´ 16 surfaces) were evaluated per timepoint to characterize cortical breaks as pathological (erosion) or physiological, and to quantify erosion width and depth. Reliability was evaluated by intraclass correlation coefficients (ICC), percentage agreement, and Light k; change over time was defined by means ± SD of erosion numbers and dimensions.Results.ICC for the mean measurements of width and depth of the pathological breaks ranged between 0.819–0.883, and 0.771–0.907, respectively. Most physiological cortical breaks were found at the palmar PB, whereas most pathological cortical breaks were located at the radial MH. There was a significant increase in both the numbers and the dimensions of erosions between baseline and follow-up (P= 0.0001 for erosion numbers, width, and depth in axial plane;P= 0.001 for depth in perpendicular plane).Conclusion.This exercise confirmed good reliability of HR-pQCT erosion measurements and their ability to detect change over time.
Whole-body MRI Quantification for Assessment of Bone Lesions in Chronic Nonbacterial Osteomyelitis Patients Treated With Pamidronate: A Prevalence, Reproducibility, and Responsiveness Study
Authors: Panwar Jyoti , Tolend Mirkamal , Lim Lillian , Tse Shirley M. , Doria Andrea S. , Laxer Ronald M. , Stimec Jennifer 
Published: September 2020

ObjectiveThe purpose of this study was (1) to assess the interreader reliability in detecting and scoring the inflammatory bone lesions in pediatric patients with chronic nonbacterial osteomyelitis (CNO) by using whole-body magnetic resonance imaging (WB-MRI), and (2) to evaluate the responsiveness of the MRI-detected CNO lesions to pamidronate therapy.MethodsEighty-eight WB-MRI examinations were independently reviewed and scored by 2 radiologists blinded to clinical details in 32 retrospectively enrolled pediatric patients with CNO. Inflammatory bone lesions, soft tissue abnormality, and bony structural changes were scored before and after pamidronate therapy. Lesion responsiveness was calculated by using standardized response mean and interreader reliability was assessed by k statistics.ResultsThere was good to excellent interreader agreement for the detection and quantification of bone lesions. After the first cycle of pamidronate in all 32 patients, 96 of the 279 lesions (34%; after excluding 108 lesions of hand and feet) resolved, whereas in a subset of 11 patients with 2 or more cycles, 76% of lesions resolved after the second cycle. Twenty-one (7.5%) lesions worsened and 46 (16.4%) new lesions developed after 1 cycle in all 32 patients. In these 11 patients, the number of worsened lesions reduced to 2 (2%) and new lesions to 14 (14.9%) after the second cycle as detected on MRI. Vertebral lesions had the highest response to treatment.ConclusionWB-MRI is a reliable tool for objective quantification and assessment of response to treatment of pediatric CNO bone lesions and could be used to monitor disease activity for clinical and research purposes.
Après la crise du Covid : vers la démarche participative d’équipe
Authors: Colombat Philippe , Altmeyer Antonia , Bauchetet Chantal 
Published: September 2020

La souffrance au travail dans le monde médical est une triste actualité cette année avec la crise du coronavirus, mais également avec les conséquences des restructurations successives et répétitives du système de santé qui, au nom de l’équilibre budgétaire, semblent oublier l’augmentation du nombre de maladies chroniques et le vieillissement de la population. En contrepartie, la qualité de vie au travail (QVT) est une préoccupation majeure du gouvernement actuel avec la mise en place de la stratégie de la QVT des personnels de santé. Depuis une trentaine d’années, l’association francophone des soins oncologiques de support 1 (AFSOS) propose un modèle organisationnel de service pour améliorer la QVT des soignants : la démarche participative.
« Designer » la Régulation Émotionnelle Collective aux Urgences : l’incontournable compétence de demain
Authors: Monier Hélène 
Published: September 2020

Une étude de cas menée dans un service d’Urgences suscite un étonnement par rapport aux théories disponibles sur le sujet des émotions et de la régulation des affects en contexte de care, et fait émerger un concept, absent de la littérature. Afin de compenser le défaut, l’incomplétude ou l’ambiguïté des règles émotionnelles officielles, les urgentistes peinent à construire et à faire vivre des règles autonomes, socio-émotionnelles, dans les groupes restreints de travail. Des entretiens et un travail ethnographique d’immersion nous conduisent à discerner l’expression de régulations émotionnelles au sens de Gross (1998), collectives. Cet article a pour objectif de définir le concept de Régulation Émotionnelle Collective (REC), associant la théorie de la régulation émotionnelle de Gross (1998) en psychologie, à celle de la régulation sociale (TRS) de Reynaud (1988) en sociologie des organisations. Les cadres de santé détiennent un rôle majeur de déploiement de leurs compétences émotionnelles, afin de comprendre et de réguler les émotions vécues et travaillées par les urgentistes. « Designer » et animer la REC permet de produire le « petit sens » au quotidien, et fait écho à l’importance du soutien social préservant la santé et favorisant la qualité de service.
Morphology and the position of the pterion in a Sri Lankan population
Authors: Disanayake J. , Sampath H. , Manawaratne R. , Nawarathna G. , Disanayake M. , Peiris R. , Nanayakkara D. 
Published: September 2020

Objective: The present study was conducted to describe the morphology of the pterion, and its position in an adult Sri Lankan population. Materials and methods: Fifty eight pteria of twenty nine adult skulls of known gender in a Sri Lankan population were analyzed to determine the sutural morphology of the pterion, and its precise location in relation to the posterolateral aspect of the frontozygomatic suture, midpoint of the zygomatic arch, anterior and superior most point of the external auditory meatus, and the inferior most point of the mastoid process. Results: The predominant type of pterion observed was sphenoparietal (82.5%), followed by stellate (8.7%), frontotemporal (5.3%), and epipteric types (3.5%). The mean distances from the center of the pterion to the frontozygomatic suture were measured as 31.11 ± 5.02 mm and 26.98 ± 3.45 mm; to the zygomatic arch, 38.92 ± 3.55 mm and 36.16 ± 3.83 mm; to the mastoid process, 81.54 ± 4.62 mm and 77.79 ± 3.88 mm; and to the external acoustic meatus, 53.62 ± 2.58 mm and 51.91 ± 2.98 mm, in males and females, respectively. Conclusion: The pterion in the males was positioned at a higher point from the zygomatic arch than in females while sphenoparietal type of pterion predominates in the Sri Lankan population.
Effects of the Incorporation of Alpha-Tocopherol as Antioxidant on Biological and Physicochemical Properties of Calcium Hydroxide Associated with Bioactive Vehicle
Authors: De Souza Vitor , Zaniboni Joissi Ferrari , Escalante-Otárola Wilfredo Gustavo , Matsumoto Mariza Akemi , Bighetti Claudia Cristina , Kuga Milton Carlos 
Published: September 2020

AbstractAim: The aim of this study to evaluate the effects of 10% alpha-tocopherol (10AT) or 20% alpha-tocopherol (20AT) incorporation on biological compatibility, pH, and calcium release of calcium hydroxide (CH) paste associated with 2% chlorhexidine digluconate (CHX). Materials and Methods: Four groups were evaluated: CH, CH-CHX, CH-CHX-10AT, and CH-CHX-20AT. For biological compatibility test, polyethylene tubes containing several pastes were implanted in Wistar rats' subcutaneous tissue (n = 28). After 48 h and 7, 14, and 21 days postimplantation, the specimens were removed and subjected to histologic and histomorphometric analysis. The number of inflammatory cells was evaluated. For pH and calcium release analysis, the pastes were placed individually (n = 10) in plastic tubes and immersed in deionized water. The calcium release and pH changes were evaluated in 24 and 48 h and 7, 14, and 21 days. All data were submitted to Kruskal–Wallis test (α = 0.05). Results: Concerning biological compatibility, all materials shown a similar decidual response (P > 0.05). In the first hours, there was as increase in the number of inflammatory cells, inducing an expressive inflammatory response. After 14 days, inflammation reaction decreased and collagen fiber was organized for the tested pastes (P = 0.05). The pH analysis of the groups maintained the same relationship during the different periods evaluated: the CH and CH-CHX groups showed higher values and were similar to each other (P > 0.05), followed by the CH-CHX-10AT and CH-CHX-20 AT groups. Regarding the amount of calcium ions, in the initial (24 hours) and final (21 days) periods, the groups did not present differences between them (P > 0.05). Conclusion: The 10AT or 20AT, as an antioxidant agent, incorporation to CH and 2% CHX paste negatively affected biological and physicochemical properties.
Knowledge and Perception about Health Risks Associated with Tobacco Habit — A Survey
Authors: Sushanthi L Casilda , Santhanam Archana , Sherlin Herald J. , Jayaraj Gifrina , Don Kanchi Ravi 
Published: September 2020

Abstract
Introduction: Nicotiana tabacum, a South American herb, is the main source of tobacco. The use of tobacco for medicinal purposes emerged in the 1400s, and later in 1800–1900, the presence of nicotine in tobacco was discovered, leading to tobacco abuse. Apart from tobacco use, manufacturing tobacco, packaging, and even disposal of cigarette butts and packages have an environmental effect. Tobacco is available in different types from manufactured cigarettes, hookahs, bidis, cigars, cheroots, and chewing tobacco. The main aim of the study was to assess the knowledge of health risks associated with tobacco habit in tobacco users. Materials and Methods: A descriptive cross-sectional survey was conducted among tobacco users visiting a private dental institution. A total of 100 participants were involved, and a questionnaire containing 21 closed-ended questions was prepared and distributed online using Google Survey Forms. The responses were collected, tabulated in excel, and statistically analyzed using SPSS. Chi-square test was done to assess the knowledge of the participants regarding the health risks of tobacco. Results: The majority of the participants smoked everyday for the past 3–10 years. Manufactured cigarettes were predominantly used among the 100 participants. The majority of the participants were aware that smoking causes lung and heart diseases in adults. Most of the participants were also aware of passive smoking. Conclusion: Immense programs regarding disposal of cigarette butts and awareness in young adults should be practiced to reduce the consumption of tobacco.
Enterococcus faecalis-Induced Nuclear Factor-Kappa Beta and Osteocalcin Expressions in Rat's Periapical Tissue Damage
Authors: Mooduto Latief , Sunariani Jenny , Samadi Karlina , Ardany Dwi W Frans , Kartini S Yulianti , Bachtiar Boy Muchlis , Bachtiar Endang Winiati 
Published: September 2020

Abstract
Background/Aims: Nuclear factor kappa beta (NF-κB) is a member of the transcription factor family, and it plays a key role in coordinating the expression of genes in many chronic inflammatory diseases. The main etiology of endodontic treatment failure is caused by bacteria in root canal, including Enterococcus faecalis. The aim of this study to determine NF-κβ and osteocalcin expressions during the periapical tissue damage due to induction of E. faecalis. Materials and Methods: Fifty-four male rats were randomly divided into two main groups, each of which had three subgroups. In Group C (control), every tooth was induced only by sterile brain–heart infusion broth (BHIb). Group C had three subgroups, namely Group C3 with 3 days inductionprocess, Group C10 with 10 days induction process, and Group C21 with 21 days induction process. In Group T, every tooth was induced by 10 μl of BHI-b E. faecalis ATCC212 (106 CFU). Similarly, Group T also had three subgroups, namely Group T3 with 3 days induction process, Group T10 with 10 days induction process, and Group T21 with 21 days induction process. The animals were sacrificed based on their group schedule and then prepared for histological and immunohistochemical examinations of periapical tissue. Afterward, the expressions of NF-κβ and osteocalcin were calculated on the light microscope. Results: The results revealed that the number of cells expressed of NF-κβ and osteocalcin increased significantly in all sub-groups of Group B induced by E. faecalis compared to the control group. Conclusion: It can be concluded that the number of cells expressed NF-κβ and osteocalcin increase during the periapical tissue damage induced by E. faecalis.
Correlation of Gingival Phenotype and Schneiderian Membrane Thickness: A Cross-Sectional Study
Authors: Kajan Zahra Dalili , Maleki Dina , Soleimani Bahareh Afjeh , Malekzadeh Meysam 
Published: September 2020

Abstract
Background and Purpose: Gingival phenotype (GP) can be measured in patient's clinical evaluations to predict the Schneiderian membrane thickness (SMT). Materials and Methods: In this analytic observational cross-sectional study, cone-beam computed tomography (CBCT) images of 310 patients requiring implant surgery in the first or second molar area of maxilla were selected. The GP was determined by inserting a periodontal probe into gingival sulcus. If the outline of the underlying periodontal probe could be seen through the gingival, it was categorized as thin; if not, it was recorded as thick. The examiner measured SMT by calculating the average thickness of the Schneiderian membrane in three sequent cuts of CBCT images. All analyses were performed using SPSS Version 24 software. To analyze the data, independent samples test, Pearson correlation, and linear regression were performed. The level of significance was set at P = 0.05. Results: Age had no statistically significant relation with SMT and GP (P = 0.666 and P = 0.842, respectively). The difference of SMT among males and females was not statistically significant (P = 0.196). In terms of GP, males and females were statistically significantly different such that females had thin GP more frequently compared to males (P = 0.003). SMT was statistically significantly thinner in patients with thin GP compared to those with thick GP (P ≤ 0.001). Conclusion: It may be suggested that GP is an important clinical predictor for SMT, particularly if CBCT evaluations or histological examinations are not possible.
Sub-acute evaluation of artesunate, amodiaquine and their combination on muscular coordination and morphology of the cerebellum of Wistar rats
Authors: Popoola AbdulGafar N. , Imosemi Innocent O. 
Published: September 2020

Artemisinin Combination Therapy (ACT) is currently the best choice for the treatment of malaria. Artesunate-amodiaquine combination is one of the most commonly used ACTs in Nigeria with a very potent efficacy but not without side effects involving motor coordination. Currently, there is dearth of information on its sub-acute effect on the cerebellum. This study investigated the sub-acute effects of artesunate (AS), amodiaquine (AQ) and artesunate + amodiaquine combination (AS+AQ) on the motor coordination, oxidative markers and morphology of the cerebellum of adult Wistar rats. Forty adult male Wistar rats were randomly divided into 4 groups, n=10. The rats were administered orally for 3 days, distilled water (control, CT), 4 mg/kg body weight AS, 10 mg/kg body weight AQ and 4 mg/kg AS + 10 mg/kg AQ. Rats were weighed, assessed for motor coordination and sacrificed on day 15. Brain tissues were excised and some cerebella preserved for oxidative stress and antioxidants while others were fixed in 10% NBF for histological and immunohistochemical studies. Results showed significant decreased body weight of the AQ group compared to the CT; decreased time of fore limb grip in the AS and AQ groups compared with the CT. Test groups showed increased LPO and NO, and lower levels of SOD, CAT and GSH compared with the control. Artesunate and AQ had significantly reduced number of Purkinje cells, AQ and AS caused increased astrocyte population and increased expression of iNOS. Sub-acute studies of Wistar rats treated with artesunate, amodiaquine and their combination induced oxidative stress, reduced their motor function and impaired morphology of the cerebellum.
Keywords: Artesunate, amodiaquine, behaviour, cerebellum, histology, immunohistochemistry.
Détermination par caméra piège des périodes d’activité de quelques mammifères terrestres au Parc National de Taï
Authors: N’goran N’guessan Serge Pacôme , Cappelle Noémie , Bitty Eloi Anderson , Normand Emmanuelle , Kablan Yves Aka 
Published: September 2020

Les périodes d’activité des animaux difficilement observables des forêts primaires sont peu connues. Des caméras pièges ont été utilisées pour établir les périodes d’activité de quelques mammifères au Parc national de Taï. Ces caméras non appâtées ont été installées d’octobre 2016 à août 2017. L’enregistrement de l’heure et la date de chaque observation a permis de déterminer des activités nocturnes, diurnes et cathémérales (actif le jour et la nuit) des espèces à travers le pourcentage des vidéos obtenues. Les heures d’activité pour chaque espèce étaient concentrées autour du vecteur moyen (heure moyenne autour de laquelle sont concentrées les heures d’activité de l’espèce) et réparties de manière non-uniforme pendant la période de 24h. Les mammifères de petite masse corporelle (< 10 kg) avaient des tendances nocturnes alors que ceux de grande masse corporelle (> 10 kg) avaient des tendances nocturnes, diurnes ou cathémérales. Certaines espèces cathémérales ont montré des périodes d’activité à prédominance diurne ou nocturne et doivent faire l’objet d’études supplémentaires enfin de connaître les facteurs influençant leur régime d’activité.Mots clés : caméra piège, taux de capture, mammifères, vecteur moyen.

English Title: Activity periods of some terrestrial mammals by using camera traps in Taï National ParkDetermination of cryptic animal’s activity periods is problematic in primary forests and reminds poorly known. Hence, in the Tai National Park, camera traps were used to establish the periods of activity of some mammals. These non-baited cameras were installed in the research area of the park from October 2016 to August 2017. Recording the time and date of each observation enabled to determine nocturnal, diurnal and cathemeral activities of each species through the percentage of videos obtained. Hours of activity for each species were concentrated around the mean vector and were not uniformly distributed over the 24-hour period. Furthermore, mammals with smaller body mass (<10 kg) had nocturnal tendencies whereas those with larger body mass (> 10 kg) had nocturnal, diurnal or cathemeral tendencies. Certain cathemeral species have predominantly shown day or night periods of activity and must be subject to further studies to find out more about the factors influencing their regimes of activity.Keywords: camera trap, detection rate, mammals, mean vector.
Effet des extraits aqueux de <i>Calotropis procera</i> sur les principaux ravageurs du chou en culture au Sénégal
Authors: Ngom Saliou , Diome Toffène , Diop Bocar , Sembene Mbacké 
Published: September 2020

Au Sénégal, le chou est l’un des légumes les plus cultivés et consommés, de par son cycle relativement court (60-90 jours après repiquage) et sa possibilité d’être cultivé toute l’année. Cependant il est attaqué par plusieurs ravageurs tels que Plutella xylostella (L.) (Lepidoptera, Plutellidae), Hellula undalis (F.) (Lepidoptera, Pyralidae) et Spodoptera littoralis (B.) (Lepidoptera, Noctuidae). L’objectif de cette étude était de contribuer à la lutte contre ces ravageurs du chou en culture dans la zone des Niayes en utilisant les extraits aqueux à base de feuilles de Calotropis procera (Apocynaceae). L’étude a été menée sur 28 parcelles élémentaires dans la zone des Niayes (durant la période du 3 janvier au 22 mars 2019). Les formulations d’extrait de feuilles de C. procera utilisant comme solvant l’eau de robinet et l’eau de puits (ER et EP), appliquées à des temps différents le matin (ERM, EPM) et le soir (ERS, EPS) ont montré leurs efficacités sur les larves de P. xylostella et H. undalis. Par contre, les extraits ne sont pas efficaces sur S. littoralis (P-value= 0,672). En plus de leurs effets biocides, les extraits à base de feuilles de C. procera semblent accélérer la croissance des plants de chou. La nature du solvant et la période du traitement n’ont pas montré une différence significative.Mots clés : Biocide, Brassicassée, Niayes, lutte biologique
English title: Aqueous extracts effect of Calotropis procera on the principal cabbage pests in culture in Senegal
In Senegal, the cabbage is one of the most cultivated and consumed vegetables, from its relatively short cycle (60-90 days after road repair) and the possibility of being cultivated all the year. However it is attacked by several pests such as Plutella xylostella (L.) (Lepidoptera, Plutellidae), Hellula undalis (F.) (Lepidoptera, Pyralidae) and Spodoptera littoralis (B.) (Lepidoptera, Noctuidae). The objective of this study was to contribute on protect against cabbage pests in culture in the zone of Niayes by using the aqueous extracts containing sheets of Calotropis procera (Apocynaceae). The study was undertaken on 28 elementary pieces to in the zone of Niayes (during the period of January 3 at March 22, 2019). The formulations of extract using as solvent the water of tap and the water of well (ER and EP), applied to different times morning (ERM, EPM) and evening (ERS, EPS) showed their effectiveness on larvae of P. xylostella and H. undalis. On the other part S. littoralis was resistant to treatment (P=0,672) confirms it. In addition to their biocides effects, the extracts containing sheets of C procera seem accelerated the cabbage patches growth. The nature of solvent and the treatment period did not show a significant difference.Keywords: Biocide, Brassicasseae, Niayes, biological control