bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cidade saudável: estratégias para intervenções na frente d’água do Centro Expandido Continental do Recife, Brasil.
Authors: Barretto Natália Carneiro Leão Rego , Camara Andrea Dornelas 
Published: May 2020

A presente pesquisa investiga relações entre a qualidade do espaço urbano e a saúde pública, ou seja, como o espaço urbano pode influenciar a nossa saúde (física ou mental). O seu objetivo desenvolve-se a partir do entendimento da potencialidade de espaços públicos em contato com elementos e paisagens naturais e como estes espaços tornam-se oportunos para o aumento dos índices positivos de saúde pública. Afim de propor diretrizes e estratégias para a melhoria destes espaços, realizou-se o estudo da qualidade dos espaços públicos existentes na frente d’água do rio Capibaribe, no Centro Expandido Continental da cidade do Recife, Brasil. A pesquisa reuniu diagnóstico do território e estudo de estratégias associadas ao conceito norteador, a saúde urbana.
The present research investigates relations between the quality of urban space and public health, that is, how urban space can influence our health (physical or mental). Its purpose is to understand the potential of public spaces in contact with natural elements and landscapes and how these spaces become opportune for the increase of positive public health indexes. In order to propose guidelines and strategies for the improvement of these spaces, a study was carried out on the quality of public spaces on the water front of the Capibaribe River, in the Continental Expanded Center of the city of Recife, Brazil. The research gathered a diagnosis of the territory and study of strategies associated to the guiding concept, urban health.
Etnización y autenticidad del espacio público: reflexiones sobre la vocación urbana del Barrio Chino porteño
Authors: Ciocoletto Guadalupe 
Published: May 2020

La ciudad de Buenos Aires, bajo los efectos de la globalización, se ha transformado en un punto atractivo para los negocios, y el turismo se ha convertido en un importante recurso económico. A ello se le suma la inmigración como un fenómeno nuevamente en alza, y al cual entendemos como un importante modelador urbano. Esta realidad nos lleva a preguntarnos: ¿qué imágenes se generan del otroen la ciudad? ¿qué usos propone la cuidad de su imagen globalizada? Analizaremos algunas decisiones sobre el llamado Barrio Chinoporteño, renovado varias veces en los últimos años: estas modificaciones habrían dado lugar a políticas de identidad y alteridad donde los símbolos identitarios-culturales son resaltados no solo por los propios habitantes sino por los espacios de poder, creando un área urbana altamente etnizada donde la diferencia cultural es resaltada para convertirse en atractivo.
The city of Buenos Aires, under the effects of globalization, has become an attractive point for business, and tourism turned into an important economic resource. To this, immigration is added as a phenomenon again on the rise, and which we understand as an important urban modeler. This reality leads us to ask ourselves: what images are generated about the other in the city? What uses does the city propose for its globalized image? We will analyze some decisions about the so-called Barrio Chino de Buenos Aires, renewed several times in recent years: these modifications might have led to policies of identity and alterity where the identity-cultural symbols are highlighted not only by the inhabitants themselves but by the spaces of power, creating a highly ethnized urban area where cultural difference is emphasized to become an attraction.
Centralismo y formas fluidas de planificación territorial en Chile: mecanismos de gobernanza horizontal para la agenda urbana local
Authors: Marshall Catalina 
Published: May 2020

En el contexto del alto nivel de centralismo del Estado chileno, el país ha experimentado un proceso tardío y fragmentado de la descentralización de la planificación territorial, en el sentido de un traspaso significativo de atribuciones, competencias y facultades a gobiernos regionales y municipalidades. Ello resulta complejo bajo la premisa de la importancia de la descentralización gubernamental para el desarrollo de los territorios (Tocqueville, 1835; Borja y Castells, 1998; Boisier, 2010; OECD, 2013). En este artículo, se abordarán las complejidades de gobernanza de temas de planificación territorial, entre el nivel central y el nivel local (municipalidades) en Chile, desde el grado de incidencia de los municipios, en la formulación, diseño e implementación de grandes proyectos de carácter urbano y de inversión sectorial. Se expondrán los resultados enfocándose en casos claves, para demostrar nuevas modalidades de planificación, gestión y gobernanza urbana, mediante la colaboración y coordinación entre los niveles de gobierno, el sector privado, el sector académico, y la ciudadanía.
Given the high level of centralism of the Chilean State, the country has experienced a delayed and fragmented process of decentralization, in the sense of a significant transfer of planning powers to regional governments and municipalities. This is complex under the premise of the importance of government decentralization for the development of territories (Tocqueville, 1835, Borja and Castells, 1998, Boisier, 2010, OECD, 2013). This article addresses the complexities of governance of territorial planning issues between the central level and the local level (municipalities) in Chile, from the degree of incidence of municipalities, in the formulation, design and implementation of large urban and sectoral investment projects. Results will be presented focusing on key cases, to show new modalities of planning, management and urban governance, through collaboration and coordination between levels of government, the private sector, the academic sector, and citizens.
Calçadas com diferentes tipos e variações de pisos: uma avaliação estética por grupos com distintas formações educacionais
Authors: Knapp Chrystiane , Reis Antônio Tarcísio da Luz 
Published: May 2020

Este artigo analisa as preferências de pisos e o impacto estético das variações dos pisos de calçadas ao longo da mesma quadra, na percepção de três grupos de respondentes com distintas formações educacionais. Foram apresentadas para a análise de impacto estético doze vistas de pisos mais recorrentes e três percursos de calçadas com diferentes níveis de variações de pisos ao longo da mesma quadra, conforme segue: (i) alta heterogeneidade: grande variedade de pisos; (ii) média heterogeneidade: média variedade de pisos, e (iii) homogeneidade, sem variação de pisos. Os dados foram coletados através de questionários on-line para moradores de Porto Alegre e RMPA, categorizados em: (38) arquitetos; (69) não arquitetos com formação universitária e (10) respondentes sem formação universitária, e analisados através de testes estatísticos não paramétricos. Os principais resultados evidenciam maior preferência por pisos de tamanhos e cores uniformes, assim como impacto positivo por percursos de calçada com pisos homogêneos.
This article analyzes the preferences of sidewalk surface and the aesthetic impact of the variations of the paving along the same block, in the perception of three groups of respondents with different educational backgrounds. Twelve more recurrent sidewalk surface views and three sidewalk paths with different levels of paving variation along the same block were presented for the aesthetic impact analysis, as follows: (i) high heterogeneity: wide variety of paving; (ii) average heterogeneity: medium variety of paving, and (iii) homogeneity, without variation of paving. Data were collected through online questionnaires for residents of Porto Alegre and RMPA, categorized in: (38) architects; (69) non-architects with university education and (10) respondents without university education, and analyzed through non-parametric statistical tests. The main results show a greater preference for uniform size and color of sidewalk surface, as well as positive impact on sidewalk paths with homogeneous paving.
Lineamientos para el desarrollo urbanístico de la periferia: estudio de la Zona Sur de Córdoba Argentina
Authors: Martínez Mónica , Schiavoni María Julia 
Published: May 2020

El presente trabajo forma parte de la investigación doctoral Conicet, que aborda el estudio de los procesos de crecimiento del Área Metropolitana de Córdoba, a partir de un antecedente disponible en la Zona Sur de la ciudad -estudio de la Agencia para el Desarrollo Económico de Córdoba- (ADEC). La periferia Sur es uno de los sectores de mayor dinámica y complejidad metropolitana. La estructura urbano-territorial refleja características urbanas, suburbanas y rurales, de gran conflictividad funcional, ambiental y social. La distribución de las actividades económicas, las políticas de ordenamiento y el desconocimiento de los valores de conservación del territorio, ponen en evidencia un territorio en desequilibrio, con una realidad física y socio ambiental compleja. En este texto se ensayan múltiples enfoques sobre ésta problemática urbano-metropolitana abordando de lo particular a lo global y viceversa.
The present work is part of a Conicet PhD research, which deals with the study of the dynamic processes of growth of the metropolitan area of Córdoba, based on a background available in the southern area of the city -study of the Agency for Economic Development of Córdoba- (ADEC). The southern periphery is one of the most dynamic and complex metropolitan sectors. The urban-territorial structure reflects urban, suburban, periurban and rural characteristics of great functional, environmental and social conflict. The distribution of the economic activities, the policies of ordering and the ignorance of the conservation values of the territory, show a territory in imbalance and physical and socio-environmental conflict. In this text, multiple approaches to this urban-metropolitan problem are develop, addressing the global to the particular and vice versa.
Plan de manejo de las problemáticas ambientales: estudio de riberas de ríos y arroyos urbanos de la ciudad de Salta
Authors: Miguel Sebastián , Faggi Ana 
Published: May 2020

Se propone brindar respuestas integrales e interdisciplinarias sobre la problemática ambiental de los ríos y arroyos urbanos de la Ciudad de Salta vinculados a los usos del suelo y la problemática socio-ambiental de las infraestructuras urbanas. Desarrollar una evaluación integral que permite establecer un diagnóstico de problemáticas y casos de referencia, con el objeto de proponer un plan de manejo de las problemáticas ambientales analizadas. La investigación toma como premisa la Nueva Agenda de Desarrollo Sostenible (ONU), en donde se seleccionan aquellos objetivos globales con metas específicas aplicados al área de estudio para erradicar la pobreza, proteger el planeta y asegurar la prosperidad que deben alcanzarse hasta en 2030. El resultado de este trabajo servirá como una herramienta de planificación para gobiernos, del sector privado y de la sociedad civil, con el fin de lograr el desarrollo equilibrado del hábitat.
We propose to provide comprehensive and interdisciplinary responses on the environmental problems of the rivers and urban streams of the City of Salta linked to land uses and the socio-environmental problems of urban infrastructures. To develop an integral evaluation that allows to establish a diagnosis of problems and reference cases, in order to propose a management plan for the environmental problems analyzed. The research takes as a premise the New Agenda for Sustainable Development (UN), which selects those global objectives with specific goals applied to the study area to eradicate poverty, protect the planet and ensure the prosperity that must be achieved until 2030. The result of this work will serve as a planning tool for governments, the private sector and civil society, in order to achieve a balanced habitat development.
Capital social comunitario y procesos institucionales: Barrio Santa Clara, Municipio Distrito Central, Honduras
Authors: Ayes Rivera Ixchel 
Published: May 2020

En un contexto de informalidad, el Capital Social Comunitario (CSC) es un factor determinante para que las comunidades de los barrios informales logren satisfacer sus necesidades básicas y sean reconocidos por las instituciones prestadoras de servicios y administradoras del territorio municipal. Esta investigación se concentra en las dinámicas sociales y en las redes internas del barrio Santa Clara a través de un estudio exploratorio y descriptivo con metodología mixta, que permitió describir la situación socio-económica de la comunidad, dimensionar el CSC a través de sus recursos asociativos (confianza, reciprocidad y cooperación) y analizar la situación sobre la tenencia de la tierra, vivienda y acceso a servicios urbanos, señalando la incidencia que tienen las instituciones externas en la organización comunitaria y en los procesos de consolidación barrial.
In a context of informality, the Community Social Capital (CSC) is a determining factor for informal neighborhood communities to satisfy their basic needs and be recognized by the public service providers and the municipal territory managers. This research focuses on the social dynamics and internal networks of the Santa Clara neighborhood through an exploratory and descriptive study with a mixed methodology, which allowed describing the socioeconomic situation of the community, dimensioning the CSC through its associative resources (trust, reciprocity and cooperation) and analyze the situation of land tenure, housing and access to urban services, noticing the influence that external institutions have on the community organization an neighborhood consolidation processes.
El suelo agrícola como elemento clave en latransformación de territorios en transición: caso de estudio Cuenca - Ecuador
Authors: Albarracin Vélez Giovani , Contreras Escandón Christian 
Published: May 2020

El presente estudio aborda una problemática socio ambiental dentro de la franja territorial conocida como periurbano, según el cual el avance de la urbanización significa el destrozo del medio natural; se toma como caso de estudio las parroquias catalogadas como rural Misicata y urbana Yanuncay en la ciudad de Cuenca que se encuentran dentro de este espacio. Los resultados más importantes proponen una reconsideración de las metodologías e instrumentos con los cuales la ciudad está siendo planificada, ya que esta ha permitido la pérdida y fragmentación de extensas áreas boscosas y suelos agrícolas, el estudio concluye de manera satisfactoria con una propuesta de escenarios para una nueva organización rural - urbana que logre un interfaz campo-ciudad dentro de una lógica de complementariedad, que permita un crecimiento urbano sostenibleponiendo en valor el suelo agrícola, promoviendo su conservación y la conectividad de flora y fauna.
The present study addresses an environmental problem within the territorial fringe known like peri-urban, according to which urban expansion means the destruction of the natural environment, it is taken as a study case the parish of Misicata considered as rural area and Yanuncay parish like urban site both located in the city of Cuenca and which are into this área, the most important results sugest a reconsideration of the methodologies and instruments with which the city is being planned, since this has allowed the loss and fragmentation of extensive forest areas and agricultural soils. The study concludes satisfactorily with a proposal of three scenarios and a theoretical framework, that apply rural organization and achieve a field-city interface within a complementarity logic, which allows urban growth with equal densities or higher than the current, facilitating the conservation of agricultural land and the connectivity of flora and fauna.
Rapid identification of melioidosis agent by an insulated isothermal PCR on a field–deployable device
Authors: Chua Kek Heng , Tan E. Wei , Chai Hwa Chia , Puthucheary SD , Lee Ping Chin , Puah Suat Moi 
Published: May 2020

Background
Burkholderia pseudomallei causes melioidosis, a serious illness that can be fatal if untreated or misdiagnosed. Culture from clinical specimens remains the gold standard but has low diagnostic sensitivity.

Method
In this study, we developed a rapid, sensitive and specific insulated isothermal Polymerase Chain Reaction (iiPCR) targeting bimA gene (Burkholderia Intracellular Motility A; BPSS1492) for the identification of B. pseudomallei. A pair of novel primers: BimA(F) and BimA(R) together with a probe were designed and 121 clinical B. pseudomallei strains obtained from numerous clinical sources and 10 ATCC non-targeted strains were tested with iiPCR and qPCR in parallel.

Results
All 121 B. pseudomallei isolates were positive for qPCR while 118 isolates were positive for iiPCR, demonstrating satisfactory agreement (97.71%; 95% CI [93.45–99.53%]; k = 0.87). Sensitivity of the bimA iiPCR/POCKIT assay was 97.52% with the lower detection limit of 14 ng/µL of B. pseudomallei DNA. The developed iiPCR assay did not cross-react with 10 types of non-targeted strains, indicating good specificity.

Conclusion
This bimA iiPCR/POCKIT assay will undoubtedly complement other methodologies used in the clinical laboratory for the rapid identification of this pathogen.
Preparation, Characterization and Biological Efficacy of Eucalyptus Oil Nanoemulsion against the Stored Grain Insects
Authors: Mohammed Tahany G. M. , Nasr M. E. H. 
Published: May 2020

Nanotechnology has enormous potential for developing alternative pest control strategies and reducing the risk of insecticide molecules. The present study aimed to develop a stable nanoemulsion (NE) of eucalyptus oil (EO) by the spontaneous emulsification method and evaluate its insecticidal and repellent effect against Sitophilus oryzae (L.), Rhizopertha dominica (F.) and Tribolium-castaneum (Herbst.). The prepared nanoemulsion formulation having a small particle size 8.57 nm with polydispersity index (PDI) 0.28. The study of the stability and physicochemical properties showed that the prepared formulation had good physical stability without any change in the macroscopic parameters. In addition, results showed that theinsecticidal activity of the prepared NE was higher than the original EO against the three tested insect speciesand the mortality increased with increasing concentrations and extending of exposure time. The contact toxicity of NE film revealed that, adults of R. dominica was more susceptible to all treatments followed by S. oryzae adults, while adults of T. castaneum was the least susceptible one, however, adults of S. oryzae was more susceptible followed by T. castaneum adults while, adults of R. dominica was the least susceptible one according to the fumigant toxicity and repellency. Our results suggested that the prepared formulation may be used in an integrated pest managementprogramfor controlling stored grain insects.
Variation among Different Growth Stages on Mineral Nutrient Content in Guava Fruits
Authors: Kumari Dhyanananda , Prasad Muneshwar , Ahmad Feza 
Published: May 2020

Guava is one of the most promising fruit crops of India and is considered to be one of the exquisite nutritionally valuable and remunerative crops. We are unaware of any report describing macro and micronutrient dynamics in fruit at different growth stages of guava. For conducting this experiment fruit of variety Allahabad Safeda, L-49, Lalit, Shweta, Arka Kiran, Salithong, Kimchu were collected at different stages like marble, seed hardening and harvest stage for estimation of primary nutrient (N, P, K), secondary nutrient (Ca, Mg) and micronutrient (Fe, Mn, Zn, Cu). As regards the availability of mineral nutrient contents of varieties did not follow definite trend. The nutrient content particularly N, and K were recorded highest at marble stage while as Mg and Ca was accumulated maximum in stone hardening stage and P, Zn, Fe, Cu, Mg and Mn was in harvesting stage. There was least variation was observed in Mg content. Finally, it may be concluded that for the improvement of yields and quality requirement of specific mineral and nutrients is required at different growth stages.
FOXD1‐AS1 regulates FOXD1 translation and promotes gastric cancer progression and chemoresistance by activating the PI3K/AKT/mTOR pathway
Authors: Wu Qiong , Ma Jiali , Wei Jue , Meng Wenying , Wang Yugang , Shi Min 
Published: May 2020

Gastric cancer (GC) is a common gastrointestinal cancer with a high global mortality. Recent reports have suggested that long noncoding RNA (lncRNA) are implicated in multiple aspects of GC, including pathogenesis, progression, and therapeutic response. Herein, we investigated the function of FOXD1‐AS1 in GC progression and chemoresistance. Expression of FOXD1‐AS1 was low in normal stomach tissues but was upregulated in GC cell lines. Silencing of FOXD1‐AS1 impaired GC cell proliferation and motility in vitro, and repressed tumor growth and metastasis in vivo. Importantly, FOXD1‐AS1 upregulation increased the resistance of GC cells to cisplatin. Moreover, we found that FOXD1‐AS1 promoted FOXD1 protein translation through the eIF4G‐eIF4E‐eIF4A translational complex. We also demonstrated that FOXD1‐AS1 released eIF4E from phosphorylated 4E‐BP1 and thereby strengthened the interaction of eIF4E with eIF4G by activating the PI3K/AKT/mTOR pathway. Activation of the PI3K/AKT/mTOR pathway was due to the post‐transcriptional upregulation of PIK3CA, in turn induced by FOXD1‐AS1‐mediated sequestering of microRNA (miR)‐466. Furthermore, we verified that FOXD1‐AS1 facilitated GC progression and cisplatin resistance in a FOXD1‐dependent manner. In conclusion, FOXD1‐AS1 aggravates GC progression and chemoresistance by promoting FOXD1 translation via PIK3CA/PI3K/AKT/mTOR signaling. These findings highlight a novel target for treatment of patients GC, particularly patients with cisplatin resistance.
Formononetin Ameliorates Diabetic Neuropathy by Increasing Expression of SIRT1 and NGF
Authors: Oza Manisha J. , Kulkarni Yogesh A. 
Published: May 2020

AbstractDiabetic neuropathy is commonly observed complication in more than 50 % of type 2 diabetic patients. Histone deacetylases including SIRT1 have significant role to protect neuron from hyperglycemia induced damage. Formononetin (FMNT) is known for its effect to control hyperglycemia and also activate SIRT1. In present study, we evaluated effect of FMNT as SIRT1 activator in type 2 diabetic neuropathy. Type 2 diabetic neuropathy was induced in rats by modification of diet for 15 days using high fat diet and administration of streptozotocin (35 mg/kg/day, i. p.). FMNT treatment was initiated after confirmation of type 2 diabetes. Treatment was given for 16 weeks at 10, 20 and 40 mg/kg/day dose orally. FMNT treatment‐controlled hypoglycemia and reduced insulin resistance significantly in diabetic animals. FMNT treatment reduced oxidative stress in sciatic nerve tissue. FMNT treatment also reduced thermal hyperalgesia and mechanical allodynia significantly. It improved conduction velocity in nerve and unregulated SIRT1 and NGF expression in sciatic nerve tissue. Results of present study indicate that continuous administration of FMNT protected diabetic animals from hyperglycemia induced neuronal damage by controlling hyperglycemia and increasing SIRT1 and NGF expression in nerve tissue. Thus, FMNT can be an effective candidate for treatment of type 2 diabetic neuropathy.