bluuebunny/crossref_metadata_2025_split huggingface dataset:
The process of internationalization of higher education at Kharkiv national medical university under modern conditions
Authors: Astapieva O. M. , Starenkiy V. P. , Paskevych O. I. , Grushka G. V. , Fedulenkova J. Y. , Stepanov E. P. , Maksimishin O. V. 
Published: November 2020

Background. Higher education internationalization is a process develop­ing at national, industry-specific and institutional levels, when the goals, functions and mechanism of providing educational services become inter­national in nature.
A distinctive feature of modern university education is a high rate of in­ternationalization and global introduction of teaching medical disciplines in English. International cooperation has been and remains one of the pri­orities of KNMU development. It is an integral part of the university life developing within the framework of the higher school of Ukraine in higher education world system.
Purpouse of the paper is to analyze higher medical education internation­alization development due to English medium at KNMU, new directions of improving teaching radiology and radiation medicine using modern in­novative technologies.
Material and methods. International work experience and pedagogi­cal and professional internships; experience of training foreign students of the authors as well as the teachers of others departments. The litera­ture sources and and information provided at KNMU official website have been used and analyzed.
Results. The necessary components of internationalization of teaching in English medium is a high level of English proficiency of university teaching personnel; sufficient material and technical resources; continuous training of teachers following and taking into account international teach­ing experience, participation in international educational conferences.
Conclusions. Higher education internationalization is an inevitable pro­cess developing at national, industry-specific and institutional levels; it implies that the goals, functions and mechanism of providing educa­tional services become international and have a high rate of international­ization and global implementation of teaching medical disciplines in Eng­lish medium.
Thyrotoxicosis. Clinical recommendations for diagnosis and treatment Part І
Authors: Pidchenko N. S. 
Published: November 2020

Background. Currently submitted an increased rate of thyrotoxicosis, which is characterized by polyetiology, a variety of clinical manifestations and potential treatments. Appropriate treatment requires an accurate diag­nosis and depends on the comorbidities and preferences of the patient. The aim of the study was to consider the pathogenesis, clinical picture and di­agnosis of thyrotoxicosis.
Purpose. To highlight the key points of clinical guidelines on thyrotoxi­cosis diagnosis and treatment provided by the American Thyroid Associa­tion and the American Association of Clinical Endocrinologists, US En­docrine Society dealing with diagnosis and treatment of thyroid diseases as well as the local clinical protocols of SO «Grigoriev Institute for Med­ical Radiology and Oncology of the National Academy of Medical Sci­ences of Ukraine».
Materials and methods. Based on the research in the electronic databases of last 5 years publications, which are included in the Cochrane Library, PUBMED and MEDLINE databases. Clinical guidelines are based on expert consensus and assessing the significance according to the interna­tional guideline of thyrotoxicosis.
Conclusions. Thyrotoxicosis treatment remains a challenging is­sue of modern internal medicine. Despite the existing numerous clini­cally proven protocols for the treatment of this pathology, the comorbid background of patients complicates following them. The implementa­tion of the provided protocol elements will make it possible to introduce the principles of a customized approach in thyrotoxicosis patients.
Morphological substantiation of radiomodification of preoperative radiotherapy in patients with advanced endometrial cancer
Authors: Mikhanovskij O. A. , Sukhina O. M. , Kharchenko Yu. V. , Shchyt N. M. , Fedorenko N. V. , Teplova M. A. , Moiseyenko Yu. A. 
Published: November 2020

Relevance. Endometrial cancer ranks first among oncogynecological diseases, however, 5-year survival can be achieved only in 67,7 % of patients, while 22,4 % of patients die during this period from the con­tinuation of the tumor process. Therefore, improving the complex therapy of patients with EC is very important.
Purpose of the study. to investigate therapeutic pathomorphosis in pa­tients with advanced endometrial cancer with neoadjuvantchemoradiation therapy.
Materials and methods. In order to study radiation pathomorphosis, 26 patients with ER T1-3N0-1M0-1 were examined. Group I consisted of 11 patients with a preoperative course of external radiation therapy SOD 30 Gywithout radiomodification, II – 15 patients with a preoperative course of external radiation therapy SOD 30 Gywith radiomodification.
Results and its discussion. When conducting a comparative assessment of radiation pathomorphism in patients of the study groups, it was found that when using the preoperative course of TFD on Gy 30 with radiomodi­fication, a significant decrease in the mitotic index occurs. There is also a tendency to an increase in the degree of tumor regression, the number of pathological mitoses and stromal reactions during the preoperative course of TFD on 30 Gywith radiomodification.
Conclusions. It was found that radiation therapy with EС with radiomodi­fication gives a more positive effect and regression of more than 50,0 % of the tumor volume, a decrease in its biological potential. The volume of the damaged tumor was 58,0 %, and the volume of the residual tumor was 42,0 %, that is, most of the tumor mass underwent regression.
FRONTERAS HISTÓRICO-COGNITIVAS EN LAS INTERFACES ESPAÑOL-PORTUGUÉS: FALSOS COGNADOS, INTERLENGUA Y PORTUÑOL
Authors: POZA José Alberto Miranda 
Published: November 2020

Este trabajo trata sobre una vieja cuestión en las interfaces portugués-español: el problema de los falsos cognados. En efecto, los estudios más celebrados publicados hasta ahora –entre otros: Lado (1973), Leiva (1994), Bugueño Miranda (1998), Durão (2002; 2004; 2005)– casi siempre este tema se enfocaba desde la perspectiva comunicativa o interaccionista, es decir, los autores se esforzaban en explicar cuáles eran las consecuencias, en el habla, de la existencia de este fenómeno, especialmente incidente en la interlengua de los hablantes de los respectivos idiomas enfrentados. De esta forma, proponemos una nueva visión de este fenómeno, caracterizando cognitivamente el proceso de interlengua en la mente del hablante, discutiendo el concepto tan extendido de portuñol, diferenciando tres ámbitos diferentes de aplicación y, por último, ofrecemos, siguiendo nuestras propuestas ya anticipadas en otros trabajos (MIRANDA POZA, 2013; 2015), la explicación del par “rato (esp.) / rato (port.)” desde la perspectiva histórica, un enfoque olvidado en el análisis de este tipo de hechos lingüísticos.
Optimalidasi Investasi Dana Haji Era Pandemi Covid-19
Authors: Junaedi Dedi , Aurijah Siti Chaerijah , Arsyad Muhammad Rizal 
Published: November 2020

This study aims to explore the optimal choice of Hajj financial investment through analysis of the relationship between the prospects for gold investment, Islamic stocks and rice agribusiness investment with the dynamics of exchange rates, inflation, BI-rate, pandemic cases and differences in policies in handling the Covid-19 pandemic. The method used is a mixed method between qualitative descriptions and quantitative analysis. The data used are primary and secondary data from January to August 2020. The analysis technique used is multiple regression with summy pandemic policy variables. The result: investing in gold, investing in Islamic stocks and investing in rice agribusiness can become priority options for Hajj financial investments. The prospect of investing in gold is quite bright and is not statistically significantly affected by exchange rate fluctuations, inflation, BI-rate and the case of a pandemic. Sharia stock investment (ISSI and JII indices) has good prospects even though it is influenced by the dynamics of exchange rates, inflation, BI-rate and the Covid pandemic. Likewise, the investment in rice agribusiness is considered prospective considering its greater impact on farmers and national food availability. The analysis shows that gold investment and rice agribusiness investment have a positive correlation and tend to strengthen each other.
HISTÓRIA, ACONTECIMENTO E LÍNGUA: UM OLHAR PARA OS MOVIMENTOS SOCIAIS
Authors: Vedovato Luciana 
Published: November 2020

O presente trabalho tem por objetivo discutir algumas questões fundamentais para aAnálise de Discurso: a história, o acontecimento e a língua. Como objeto de análise tomamos um movimento social de luta pela terra o Movimento dos Trabalhadores Sem Terra – MST, olhando para o modo como a história organiza alguns dizeres – como a ocupação da terra, por exemplo, e como esses dizeres se desdobram em materialidades como a língua. Partindo dessa reflexão, tomamos o MST como um acontecimento que rompe com a ordem da história e passa a descrever, registras e simbolizar suas materialidades a partir de uma posição contraditória, a partir da classe dos trabalhadores. Assim, a compreensão de língua, em uma escola do MST, não é sempre coincidente com a concepção de língua cristalizada e sedimentada que vemos de forma determinantes em outros espaços escolares.
Composición formal de las fachadas Barroco-Mestizas Arequipeñas (s. XVI-XVIII)
Authors: Coll Pla Sergio , Rios Vizcarra Gonzalo , Costa Jover Agustí , Lluis i Ginovart Josep 
Published: November 2020

<p>La arquitectura Barroco-mestiza americana se caracteriza por su riqueza formal y figurativa y por ser un estilo donde se combinan conocimientos de diferente procedencia. Siendo cierto su influjo europeo, no está determinada ni sus influencias ni su evolución. El artículo tiene como objetivo la búsqueda de los referentes medievales de esta arquitectura que podrían permanecer de manera subyacente. Para ello se estudiará la geometría de las fachadas de las Iglesias de La Merced, San Francisco, La Compañía, Santo Domingo, San Agustín y la Tercera Orden. Las fachadas de estas iglesias se caracterizan por su riqueza iconográfica.</p>
La Suisse en miniatures dans deux affiches (1942/2019) : Quelles visées touristique et politique ?
Authors: Metzger Alexis , Bussard Jonathan 
Published: November 2020

Abstract. This article shows how two Swiss posters represent a certain representation
of the Swiss territory, appropriate to the messages they try to convey. The
first one dates from 1942 and invites tourists to stay in the Pays-d'Enhaut
(canton of Vaud). The second encourages the Swiss electorate to vote for the Vert'libéral political party in 2019. Through a qualitative approach, we show that the choice of representations, a set of miniatures and sketches, is not neutral. In the light of historical, tourism and political contexts of poster production, the paper decrypts an imagery of a Switzerland for urban dwellers, green for its nature, white for its inhabitants. In both cases, Switzerland is always an island that chooses its images.
Availability of platelet-rich plasma for treatment of erectile dysfunction and associated costs and efficacy: A review of current publications and Canadian data
Authors: Britt Deron , Blankstein Udi , Lenardis Matthew , Millman Alexandra , Grober Ethan , Krakowsky Yonah 
Published: November 2020

Introduction: Platelet-rich plasma (PRP) is an increasingly used unconventional treatment option for erectile dysfunction (ED). The validity of PRP as a potential treatment for ED has been proposed in limited human trials. Furthermore, the costs associated with PRP for ED treatment are not readily promoted to patients. The goal of this review was to determine the efficacy and costs of PRP based on currently available literature and Canadian data.
Methods: A comprehensive literature review of available PRP studies and current published data pertaining to cost, availability, and provider clinics globally was conducted using the PubMed database. Physicians offering genital PRP in Canada were identified using internet searches and PRP provider directories. Physician qualifications, clinic locations, and cost information were obtained from provider websites and telephone calls to identified clinics.
Results: Availability of PRP injections offered for treating ED is increasing globally. There are currently no peer-reviewed publications to substantiate anecdotal evidence pertaining to the efficacy of PRP as a viable treatment option for ED patients. Our results indicate 19 providers for PRP injections in Canada, costing on average $1777 CAD per injection. No providers were affiliated with academic institutions and providers varied in their area of clinical speciality and training.
Conclusions: To our knowledge, there is currently no research underway investigating the clinical efficacy of PRP for ED treatment despite its broad availability and significant cost. Patients should be informed of the lack of substantiated efficacy and safety data, as the reliability of PRP treatments requires further evaluation.
Sustentabilidade social do turismo no município de Machadinho-RS
Authors: Teixeira de Lacerda Luana , Mecca Marlei Salete 
Published: November 2020

Objetivo do estudo: Analisar como se apresenta a sustentabilidade social promovida pelo turismo no parque termal no município de Machadinho – RS, por meio da aplicação de uma adaptação do Sistema de Indicadores de Sustentabilidade para Atividade Turística – SISDTur (Hanai, 2009).Metodologia/abordagem: Metodologia de natureza exploratória e descritiva, de abordagem quantitativa, na modalidade de estudo de caso, fazendo uso de levantamento, por meio da aplicação de questionários como técnica de coleta de dados.Originalidade/Relevância: O estudo apresenta dados inéditos discorrendo sobre a sustentabilidade social do turismo, expondo informações quanto ao seu desenvolvimento em destinações do interior do Rio Grande do Sul pouco pesquisadas sobre esse viés, principalmente no que tange as águas termais como principal atrativo turístico.Principais resultados: Os resultados obtidos sinalizam para o potencial sustentável das atividades existentes, onde os respondentes percebem os impactos positivos da atividade turística, não tendo nenhum indicador considerado insustentável. Porém, a existência de indicadores parcialmente insustentáveis, exige um posicionamento estratégico da gestão, visando que a destinação se desenvolva de modo que o efeito multiplicador do turismo seja sentido por toda a comunidade.Contribuições teóricas/metodológicas: Apresenta dados referentes à um tema pouco estudado na academia, contribuindo para as discussões em torno da temática, fornecendo informações relevantes para a compreensão e desenvolvimento do turismo sustentável.Contribuições sociais: Propõem uma abordagem a partir da percepção do trade turístico local, concebendo informações que possam auxiliar na gestão do turismo da destinação, e de demais localidades que buscam desenvolver o turismo em seus territórios.
Third molar agenesis in modern humans with and without agenesis of other teeth
Authors: Scheiwiller Maya , Oeschger Elias S. , Gkantidis Nikolaos 
Published: November 2020

Background
The number of teeth in the human dentition is of interest both from developmental and evolutionary aspects. The present case-control study focused on the formation of third molars in modern humans aiming to shed more light on the most variable tooth class in the dentition.

Materials and Methods
For this reason, we investigated third molar formation in a sample of 303 individuals with agenesis of teeth other than third molars (agenesis group) and compared it to a sex and age matched control group of 303 individuals without agenesis of teeth other than third molars.

Results
The prevalence of third molar agenesis in the agenesis group was 50.8%, which is significantly higher than the 20.5% in the control group (p < 0.001). The chance of a missing third molar in the agenesis group was increased by 38.3% (p < 0.001), after controlling for the agenesis in other teeth factor. When considering the amount of missing third molars per individual, a clear tendency towards more missing third molars was evident in the agenesis group compared to the control group. The frequency of bilaterally missing third molars in the agenesis group was 29% in the maxilla, as well as in the mandible, which is about three times higher than the frequency of unilaterally missing third molars (p < 0.001). In the control group, bilaterally missing third molars occurred in 8.6% in the maxilla and 8.9% in the mandible.

Conclusion
The present results indicate that genetic factors involved in tooth agenesis affect also the dentition as a whole. Furthermore, the third molars are more vulnerable to factors involved in agenesis of other teeth and they are more often affected as a whole. These findings seem to be associated with the evolutionary trend in humans towards reduced molar number.
Refutation of the Quantum Theory Principles: Theorem
Authors: Shapiro V. E. 
Published: November 2020

The theorem presented challenges the quantum mechanics and its relativistic theory generally posited as an ultimate unifying guideline of nature in fundamental and applied matters, refutes this theory, any bridges from it to the realm. We build the evidence on the rigorous statistical criteriaand arguments of compatibility at the interfaces not adduced previously against the theory. It calls in question the Born rule, particle-wave doublethink, probability sense of the quantum theory, any bridges from the theory to both Lagrangian and nonholonomic mechanics. The argumentation given to the matter of ambient noise impact at the interfaces by meaningful statistical methods paves the way towards the correct principles of causality, connectedness, robustness .
Mental time travel into the episodic future, episodic past, and episodic counterfactual past in everyday life
Authors: Branch Jared G. , Zickar Michael J. 
Published: November 2020

AbstractTo date, studies exploring the relationship of counterfactual thoughts with episodic memories and episodic future thoughts have focused mainly on voluntary mental time travel. We explore mental time travel in everyday life and find that episodic counterfactual thinking occurs to a much lesser extent than thinking about the past or the future (12%, 22%, and 54%, respectively), is used mainly for mood regulation purposes, and the temporal distribution decreases as a function of time. We observe similarities in phenomenological detail: memories and counterfactual thoughts sharing similar ratings of sensory detail, memories and future thoughts sharing similar ratings of positivity, and counterfactual and future thoughts sharing similar ratings of mental time travel. We discuss the implications of episodic counterfactual thinking in everyday life.
Identification and Characterization of a High‐Need, High‐Cost Group Among Hospitalized Patients With Systemic Lupus Erythematosus
Authors: Anandarajah Allen , Thirukumaran Caroline , McCarthy Katherine , McMahon Sean , Feng Changyong , Ritchlin Christopher 
Published: November 2020

ObjectiveTo identify a high‐need, high‐cost (HNHC) group among hospitalized lupus patients and to compare clinical and social factors of the HNHC group with those of other patients with lupus.MethodsAll hospitalizations for lupus in a tertiary care center over a 3‐year period were recorded. The number of admissions, 30‐day readmissions, length of stay (LOS), and cost of admissions were compared for high‐risk patients with those of all other hospitalized lupus patients (OHLP) during this period. We then compared clinical measures (double‐stranded DNA [dsDNA] levels, complement proteins, body mass index, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index [SDI] scores, and Case Mix Index [CMI] scores) for the HNHC cohort with those of the OHLP group. We additionally differentiated social factors (age, race and ethnicity, poverty, and medication adherence) between the 2 groups.ResultsA total of 202 patients with lupus accounted for 467 hospitalizations over the study period. The total cost of admissions was $13,192,346. Forty‐four patients had significantly higher admissions, 30‐day readmissions, and LOS. Furthermore, the cost for this group was 6‐fold that for the OHLP group, confirming the presence of an HNHC cohort. The HNHC group had significantly higher dsDNA levels, SDI scores, and CMI scores compared with the OHLP group. Infections were the most common cause of admission for both groups. Patients in the HNHC group were more likely to be African American, younger, diagnosed with lupus at an earlier age, to have lower medication adherence, and to be significantly more likely to live in areas of poverty.ConclusionA small group of patients with lupus (the HNHC group) accounts for most of the hospitalizations and cost. The HNHC group has both social and clinical factors significantly different from other patients with lupus.
Novel Framework for Measuring Whole Knee Osteoarthritis Progression Using Magnetic Resonance Imaging
Authors: Driban Jeffrey B. , Price Lori Lyn , LaValley Michael P. , Lo Grace H. , Zhang Ming , Harkey Matthew S. , Canavatchel Amanda , McAlindon Timothy E. 
Published: November 2020

ObjectiveWe developed and validated a set of composite scores that combine quantitative magnetic resonance imaging (MRI)–based measurements of hyaline cartilage damage, bone marrow lesions (BMLs), and effusion‐synovitis into composite scores.MethodsWe selected 300 participants (n = 100 for development cohort; n = 200 for validation cohort) from the Osteoarthritis Initiative with complete clinical, radiographic, and MRI data at baseline and 24 months. We used semiautomated programs to quantify tibiofemoral and patellar cartilage damage, BML volume, and whole‐knee effusion‐synovitis volume. The candidate composite scores were formed by summing changes from baseline to 24 months based on prespecified methods. We evaluated the candidate composite scores for 1) the ability to differentiate groups with and without knee osteoarthritis progression (17 radiographic and patient‐reported definitions), 2) sensitivity to change (standardized response means), and 3) relative performance relating to legacy outcome measures of knee osteoarthritis progression.ResultsThree of 13 developed composite scores qualified for testing in the validation cohort (ranked by sensitivity to change): whole‐knee cumulative cartilage damage, unweighted total knee score, and BML plus effusion‐synovitis volume. Change in cumulative cartilage damage associated with radiographic progression (Kellgren/Lawrence grade: odds ratio [OR] 1.84; joint space width progression: OR 2.11). Changes in the unweighted total knee score (OR 1.97) and BML plus effusion‐synovitis score (OR 1.92) associated with Western Ontario and McMaster Universities Osteoarthritis Index knee pain progression.ConclusionTwo composite scores emerged, reflecting discrete domains of knee osteoarthritis progression. First, cumulative damage, which is measured by a whole‐knee cartilage damage score, reflects the damage accrued over time. Second, dynamic disease activity, which is measured by a BML plus effusion‐synovitis score, relates to changes in a patient's state of disease and symptoms.