bluuebunny/crossref_metadata_2025_split huggingface dataset:
Echinochrome Pigment Improves Male Rats' Fertility
Authors: Farag Neveen Asmet , Mohamed Ayman S , El Sayed Hanan Farag , Salah EL Din Eman Y. , Tawfik Abdel Rahman A. 
Published: November 2020

Background::
Infertility is the first-rate public health problem affecting one in five married
couples globally; male causes embody a significant proportion. Natural products could be an
alternative or complementary inexpensive treatment for such matters. Echinochrome (Ech) is a natural
quinone pigment obtained from sea urchin, and it was confirmed to possess many pharmacological
properties due to its chemical activity.

Objective::
The current research paper was targeted to evaluate the potential effects of Ech on male
fertility, and to highlight the possible involved mechanisms.

Methods::
Eighteen adult male rats were randomly distributed into three groups: control (1 ml of
2% DMSO, p.o.), low dose Ech (0.1 mg/kg, p.o.), and high dose Ech (1 mg/kg p.o.).

Results::
The high dose Ech caused a significant decline in the levels of glucose, ALT, AST, ALP,
urea, Cr, uric acid, TG, TC and LDL-C and testicular tissue MDA, while it caused a significant rise
in the levels of albumin, TP, HDL-C, FSH, LH, testosterone and testicular tissue GSH activity.
Moreover, it showed a significant positive effect on the testis weight, caudal epididymis weight,
sperm count, sperm motility, sperm morphology, fructose concentration, and α-glucosidase activity.
However, no significant changes were observed in the histological examination of testicular tissue
among all groups.

Conclusion::
High dose Ech improved male rat-fertility either directly by activating the pituitarygonadal
axis, and or indirectly via enhancing the renal and hepatic functions, the lipid profile and
or the antioxidant pathways.
AS DIMENSÕES DA OFERTA... - Sistemas de distribuição de energia elétrica
Authors: PUERTAS HILTON , NOGUEIRA CARLOS ALBERTO MAYON 
Published: November 2020

distribuição de energia teve seu início no último quartil do século passado, podendo ser considerada como um marco a construção, por Thomas Alva Edison, em 1879, da primeira central elétrica para distribuição de energia à cidade de Nova Iorque. No Brasil, o pioneirismo coube à cidade de Campos, que, em 1883, tornousea primeira da América do Sul a receber iluminação pública elétrica. A distribuição elétrica, en tretanto, somente veio a constituir-se em um serviço público relativamente amplo a partir da primeira década do século, inicialmente em São Paulo (1899) e, posteriormente, no Rio (1905).
Efecto del amamantamiento restringido y complementación alimenticia sobre el peso y cortisol en becerros Simbrah
Authors: Severino-Lendechy Víctor H. , Montiel-Palacios Felipe , Gómez-de-Lucio Hiram , Peralta-Torres Jorge A. , Segura-Correa José ´Candelario 
Published: November 2020

Objetivo. Determinar el efecto del amamantamiento restringido, destete precoz y complementación alimenticia sobre las ganancias de peso y concentración plasmática de cortisol en becerros Simbrah. Materiales y métodos. Se utilizaron 120 becerros lactantes de 15 días de edad, distribuidos en dos tratamientos: T1) becerros con amamantamiento restringido, destete precoz y complementación alimenticia (n=30 machos/n=30 hembras) y T2) becerros con amamantamiento continuo sin complementación alimenticia (n=30 machos/n=30 hembras). Los becerros se pesaron al inicio del experimento, y cada 15 días para evaluar los cambios en peso corporal del destete hasta los 10 meses de edad. Los muestreos sanguíneos se realizaron al inicio del estudio y durante 10 días, entre las 7:30 y 8:30 am. Las variables de respuesta se evaluaron usando modelos lineales generales. Resultados. El peso (310.1 y 268.5 kg) y ganancia de peso postdestete (0.980 kg/día y 0.800 kg/día) fue mejor en el tratamiento T1 que, para los becerros en T2 (168.3 y 159.6 kg/día; y -0.500 y -0.480 kg/día) para machos y hembras, respectivamente. La concentración de cortisol (ng/mL) fue mayor en T1 comparado con T2 del día 0 al día 3 (p<0.05), pero el día 4 no se encontró diferencia. El T1 permitió el destete a los 3.5 meses de vida de los becerros e incrementó la ganancia de peso posdestete. Conclusiones. El peso vivo y ganancia de peso posdestete fue mejor en los animales del tratamiento T1; sin embargo, los niveles de cortisol plasmáticos se incrementaron al inicio del estudio para disminuir posteriormente.
Mobile Health Strategies to Tackle Skin Neglected Tropical Diseases With Recommendations From Innovative Experiences: Systematic Review
Authors: Carrion Carme , Robles Noemí , Sola-Morales Oriol , Aymerich Marta , Ruiz Postigo Jose Antonio 
Published: November 2020

BackgroundNeglected tropical diseases (NTDs) represent a diverse group of 20 communicable diseases that occur in tropical and subtropical areas in 149 countries, affecting over 1 billion people and costing developing economies billions of dollars every year. Within these diseases, those that present lesions on the skin surface are classified as skin NTDs (sNTDs). Mobile health interventions are currently being used worldwide to manage skin diseases and can be a good strategy in the epidemiological and clinical management of sNTDs.ObjectiveWe aimed to analyze existing evidence about mobile health interventions to control and manage sNTDs in low- and middle-income countries (LMICs) and make recommendations for what should be considered in future interventions.MethodsA systematic review was conducted of the MEDLINE, Embase, and Scopus databases over 10 years up to April 30, 2020. All types of clinical studies were considered. Data were synthesized into evidence tables. Apps were selected through a comprehensive systematic search in the Google Play Store and Apple App Store conducted between March 20 and April 15, 2020.ResultsFrom 133 potentially relevant publications, 13 studies met our criteria (9.8%). These analyzed eight different interventions (three SMS text messaging interventions and five app interventions). Six of the 13 (46%) studies were community-based cross-sectional studies intended to epidemiologically map a specific disease, mainly lymphatic filariasis, but also cutaneous leishmaniasis, leprosy, and NTDs, as well as sNTDs in general. Most of the studies were considered to have a high (5/13, 39%) or moderate (4/13, 31%) risk of bias. Fifteen apps were identified in the Google Play Store, of which three were also in the Apple App Store. Most of the apps (11/15, 73%) were targeted at health care professionals, with only four targeted at patients. The apps focused on scabies (3/15, 20%), lymphatic filariasis (3/15, 20%), cutaneous leishmaniasis (1/15, 7%), leprosy (1/15, 7%), yaws and Buruli ulcer (1/15, 7%), tropical diseases including more than one sNTDs (3/15, 20%), and NTDs including sNTDs (2/15, 13%). Only 1 (7%) app focused on the clinical management of sNTDs.ConclusionsAll mobile health interventions that were identified face technological, legal, final user, and organizational issues. There was a remarkable heterogeneity among studies, and the majority had methodological limitations that leave considerable room for improvement. Based on existing evidence, eight recommendations have been made for future interventions.
Extracting Family History of Patients From Clinical Narratives: Exploring an End-to-End Solution With Deep Learning Models
Authors: Yang Xi , Zhang Hansi , He Xing , Bian Jiang , Wu Yonghui 
Published: November 2020

Background
Patients’ family history (FH) is a critical risk factor associated with numerous diseases. However, FH information is not well captured in the structured database but often documented in clinical narratives. Natural language processing (NLP) is the key technology to extract patients’ FH from clinical narratives. In 2019, the National NLP Clinical Challenge (n2c2) organized shared tasks to solicit NLP methods for FH information extraction.

Objective
This study presents our end-to-end FH extraction system developed during the 2019 n2c2 open shared task as well as the new transformer-based models that we developed after the challenge. We seek to develop a machine learning–based solution for FH information extraction without task-specific rules created by hand.

Methods
We developed deep learning–based systems for FH concept extraction and relation identification. We explored deep learning models including long short-term memory-conditional random fields and bidirectional encoder representations from transformers (BERT) as well as developed ensemble models using a majority voting strategy. To further optimize performance, we systematically compared 3 different strategies to use BERT output representations for relation identification.

Results
Our system was among the top-ranked systems (3 out of 21) in the challenge. Our best system achieved micro-averaged F1 scores of 0.7944 and 0.6544 for concept extraction and relation identification, respectively. After challenge, we further explored new transformer-based models and improved the performances of both subtasks to 0.8249 and 0.6775, respectively. For relation identification, our system achieved a performance comparable to the best system (0.6810) reported in the challenge.

Conclusions
This study demonstrated the feasibility of utilizing deep learning methods to extract FH information from clinical narratives.
Diagnosis of the reading and interpretation of statistical graphs by undergraduate students from economic-administrative sciences programs at the University of Guadalajara
Authors: Sandoval Salvador , DelMas Robert , Celso-Arellano Pedro , Gualajara Victor , Coronado Semei 
Published: November 2020

Recently, statistical reasoning has been of vital importance not only in quantitative analysis but also in the interpretation of graphs at all educational levels. There are students that can make calculations almost immediately but are not able to interpret or present their ideas graphically. In this way, the present study seeks to conduct a diagnostic of the problems that economic-administrative students have when reading and interpreting graphs in their statistics courses. For this, a Spanish version of the test Comprehensive Assessment of Outcomes in Statistics (CAOS) was administered. This instrument allows for the determination of reasoning applied to different types of statistical graphs and in some cases to determine what type of calculation is required to do it. The instrument was applied to 138 undergraduate students from the economic-administrative area of the University of Guadalajara during January-June 2018. The results show that a large percentage of students confuse a normal distribution with a uniform one and that they are unable to distinguish that a bias can be determined from the measures of central tendency and dispersion, as well as other statistical reasoning difficulties. This may be as a result of a deficiency that exists in statistical teaching, an insufficient mathematical preparation on the part of the students, among other factors.
Psychotherapy and emancipation
Authors: Dybel Paweł 
Published: November 2020

In the article I ask the question about the place of an emancipatory task within various forms
of psychotherapy and psychoanalysis, where conversations with the patient play an important
role. This task arises on discovering that an important source of the patient’s problems are
views inherited fom cultural traditions, ones which inhibit a proper assessment of various
traumatic situations fom the past and the forms of dependence on others. Then psychotherapists and psychoanalysts are inevitably faced with the task of making the patient aware of these
limitations and forms of dependence, for only then is therapeutic progress possible. I provide
three characteristic examples of similar cases fom Polish psychiatric tradition, in which we
can speak of a similarly binding role of cultural tradition in the process of therapy. I point out
that the difcult situation the therapist then fnds themselves in lies in the fact that, on the
one hand, they have to depart fom the postulate of maintaining world-view neutrality in their
approach to the patient while, on the other hand, they cannot directly impose their own position on the patient. The therapist has to fnd a third, middle way betwee
Analysis of Factors Determining Islamic Motivation Entrepreneuship of Muslim Women Entrepreneurs in Jakarta.
Authors: Amran Ellyana , Arafah Willy 
Published: November 2020

The purpose of this study was to analyze the influence of Islamic Leadership on Islamic Motivation Entrepreneurship and the indirect effect of Islamic Leadership on Performance Islamic Business with Islamic Motivation Entrepreneurship as a mediating variable for Muslim women entrepreneurs in Jakarta. The research method used is quantitative method. Research respondents are IWAPI Muslim women entrepreneurs in Jakarta with a sample size of 354 Muslim entrepreneurs. Sample is non probability sampling by using purposive sampling. Data is collected using questionnaire and methods analysed by using Structural Equation Model (SEM). The results showed that there was influence of Islamic Leader on Islamic Business Performance either directly or indirectly through Islamic Motivation Entrepreneurship as mediation. Furthermore there is a positive influence of Islamic Leadership on Islamic Motivation Entrepreneurship; and there is a positive influence of Islamic Motivation Entrepreneurship on Islamic Business Performance.
Resolução de Problemas de inequação: análise do desempenho de licenciandos em Matemática na conversão de unidades significantes
Authors: Travassos Wilian Barbosa , Proença Marcelo Carlos de 
Published: November 2020

Este trabalho teve como objetivo analisar por meio dos processos de conversão de unidades significantes o desempenho de estudantes de Licenciatura em Matemática na resolução de problemas (situações contextualizadas) de inequações do 1º grau com uma variável. Os participantes da pesquisa foram 16 acadêmicos, sendo 4 acadêmicos de cada ano do curso de licenciatura em Matemática de uma universidade pública do Estado do Paraná. Para coleta dos dados, utilizamos cinco situações contextualizadas. Para análise, baseamo-nos na identificação das unidades significantes e, assim, no processo de conversão. Os resultados mostraram que no processo de resolução de problemas, os estudantes apresentaram facilidades no reconhecimento de unidades significantes numéricas, porém, apresentaram dificuldades em reconhecer/converter unidades significantes em Língua Natural que representam variáveis e sinais de inequação, tais como mínimo, superará, mais vantajoso. Além disso, verificamos que os estudantes do 3º e 4º ano do curso apresentaram os piores desempenhos quando comparados com os demais anos, evidenciando que a dificuldade ao resolver problemas de inequações pode se estender durante todo o processo formativo acadêmico.
Percepções de estudantes da Educação Básica sobre Saneamento Ambiental e Saúde Coletiva
Authors: Silva Cristine Santos de Souza  da , Santos Gerusa Farias dos 
Published: November 2020

No intuito de trabalhar a temática das Doenças Relacionadas ao Saneamento Ambiental Inadequado (DRSAI), o presente estudo buscou analisar as percepções de estudantes da Educação Básica em relação às estruturas do saneamento ambiental e sua interface com a saúde coletiva. A metodologia adotada envolveu a aplicação de questionários e a realização de uma intervenção pedagógica para sensibilização acerca do tema. Foram analisados 80 questionários, destes 77,5% eram alunos do Ensino Médio e 22,5% do Ensino Fundamental. Cerca de 95% dos estudantes acreditam que existem doenças e sintomas associados à água não tratada, resíduos sólidos, esgoto e à água da chuva. Ainda, 75% deles informaram o acometimento de alguma DRSAI sobre si, ou algum familiar, tendo as doenças de transmissão feco-oral apresentado maior incidência. Os resultados demonstram que a aproximação da temática com o cotidiano dos alunos favoreceu a transposição didática, contribuindo para formação de cidadãos mais críticos acerca da importância do saneamento ambiental para a promoção da saúde coletiva. Conclui-se que é necessário que ações de educação sejam realizadas no intuito de aproximar o profissional da saúde, e suas vivências, à prática didática contextualizada da educação ambiental.
PENGARUH KECERDASAN SPIRITUAL DAN DISIPLIN TERHADAP KINERJA GURU DI SD AL FIRDAUS SURAKARTA
Authors: Wibowo Ari , Febrianto R Arie 
Published: November 2020

The objectives of this study were: (1) To measure and test the influence of spiritual intelligence and discipline on teacher performance at SD Al Firdaus Surakarta. (2) To measure and test the interaction of spiritual intelligence and discipline on teacher performance at SD Al Firdaus Surakarta. The number of samples in this study were 28 respondents, with the sampling technique using a census.
The results of the regression analysis found that there was a positive and significant effect of spiritual intelligence and discipline on teacher performance at SD Al Firdaus Surakarta. The results of the t test and the F test prove that the variables of spiritual intelligence and discipline have a positive and significant effect both partially and simultaneously on teacher performance. Based on the value of the coefficient of determination which has a positive value of 0.66, it shows that the performance of teachers at SD Al Firdaus Surakarta can be explained by the spiritual intelligence and discipline variables of 66.0%, while the remaining 34.0% is explained by other factors that are not observed in this study.
Keywords: spiritual intelligence, discipline, teacher performance and regression
Prawo do tłumaczenia pokrzywdzonego w polskim procesie karnym – wybrane zagadnienia
Authors: Toruński Michał 
Published: November 2020

The analysis of the provisions of the Code of Criminal Procedure shows a clear asymmetry in the rights of the accused and the victim as regards the right to interpreting. Despite the implementation of subsequent amendments, the legislators consistently ignored the rights of the victim with regard to the right to interpreting; when they actually dealt with that issue, it was done in a fragmented and selective manner.Moreover, the exegesis of the provisions on the right to interpreting leads to the conclusion that the analyzed right is not fully regulated by the provisions of the Code of Criminal Procedure, and some extremely important normative parts of it must be decoded from the Law on the System of Common Courts. Both these spheres interpenetrate each other, which is undeniably undesirable from the point of view of the standard of legal certainty and transparency.This study aims at identifying legislative shortcomings, as well as at proposing de lege ferenda solutions in relation to the analyzed right of the victim to interpreting.
CHANGES IN FIBROSIS UNDER THE INFLUENCE OF TREATMENT OF PATIENTS WITH ALCOHOLIC CIRRHOSIS OF THE LIVER IN COMBINATION WITH OBESITY USING ADEMETHYANINIUM AND ARGININE GLUTAMATE
Authors: Matkovska N.R. 
Published: November 2020

Aim: to study the changes in liver parenchymal fibrosis under the influence of treatment of patients with alcoholic liver cirrhosis in combination with obesity using ademethionine and arginine glutamate.
Material and methods. 215 patients, diagnosed with alcoholic liver cirrhosis (ALC), took part in the study, including 66 women and 149 men aged (48.1±9.7) years and a median disease duration (5.8 ± 2.6) years. 109 people had ALC with obesity (group I) and 106 people had ALC without obesity (group II). Patients were divided into subgroups depending on the stage of decompensation according to Child-Pugh: class A – group IA (n=40), class B – group IB (n=39), class C – group IC (n=30) and IIA (n=39), IIB (n=36), IIC (n=31) groups, respectively. Depending on the treatment protocol (b protocol – basic therapy, h protocol – basic therapy in combination with ademethionine and arginine glutamate), all patients were divided into subgroups.
Results. In patients with ALC in combination with obesity, the elasticity of the liver parenchyma according to shear wave elastography and the FIB-4 index were higher than classes A, B and C compared to those in patients with ALC without obesity. According to the study results, obese patients with ALC had a more severe course of ALC according to the Child-Pugh and MELD scores. There is a direct relationship between the level of fibrosis in patients with ALC in combination with obesity according to elastography and the FIB-4 index with the severity of the disease according to the Child-Pugh ad MELD scores. The inclusion of ademethionine and arginine glutamate in the treatment regimen has improved the general condition of patients, compensated for clinical and laboratory parameters and reduced the rate of progression of liver fibrosis.
Conclusion. In patients with ALC in combination with obesity, the inclusion in the treatment of ademethionine and arginine glutamate has improved the course of the disease, as evidenced by changes in the parameters of the disease severity by Child-Pugh and MELD scores, and helped to reduce the rate of progression of liver fibrosis according to elastography and the FIB-4 index.
Predicting the development of ischemic stroke in patients with cerebral atherosclerosis and diabetes mellitus
Authors: Tronko N.D. , Kondratiuk V.E. , Cherska М.S. , Guryanov V.G. 
Published: November 2020

Cerebrovascular pathology and metabolic disorders are problems of modern health care, which are of colossal medical and social significance. A high percentage of not only mortality, but also disability determines the extreme urgency of studying their various aspects, and the presence of combined pathology requires the development of a personalized approach to the tactics of managing such patients.
The aim of our study is to predict the development of IS based on indicators of the structural and functional state of the heart and cerebral vessels and heart rate variability in patients with cerebral atherosclerosis (CA) and DM2. Materials and methods. The complex clinical and instrumental study involved 229 patients with CA 1–3 degrees. Study design: simple, prospective, non-randomized, sequential enrollment. All patients underwent instrumental examinations: transthoracic echocardiography, electrocardiography ECG, ultrasound Doppler of the vessels of the head and neck, MRI of the brain. All patients took antihypertensive and antidiabetic drugs, antiplatelet agents, statins. Results: Patients were divided into 2 groups: I - with CA 1–2 degrees, II - with CA 3 degrees (after ischemic atherothrombotic stroke (IS)). Average age = 65.1 ± 10.5 and 65.4 ± 9.1 years, respectively. The share of men was 21.2% in the 1st and 52% in the 2nd groups. The number of patients with type 2 diabetes, mean fasting glucose and glycosylated hemoglobin levels were comparable in both groups. At the time of examination, all patients achieved the target BP and T2DM compensation. In our study, for patients with CA, a negative relationship between ischemic stroke and end-diastolic size index and a positive relationship with the thickness of the interventricular septum and male sex was established, which logically explains the important role of LV geometry in the development of ischemic stroke. For patients with T2DM, a negative relationship was found between ischemic stroke and LV diastolic function and positive - with fasting glucose and IM thickness.
Conclusion: Based on multivariate regression analysis, in patients with cerebral atherosclerosis with the development of ischemic stroke, the presence of a relationship between the thickness of the interventricular septum, end-systolic size index, end-diastolic size index and the male sex was revealed (AUC = 0.94 (CI 0.91 - 0.97), but in patients with DM2 and CA - fasting glucose level, interventricular septum thickness, intima-media complex thickness and E/A AUC = 0.99 (95% CI 0.94 - 1.00).