bluuebunny/crossref_metadata_2025_split huggingface dataset:
Data Augmentation by Synthesizing IMU Data of Physiotherapeutic Exercises using Musculoskeletal Models
Authors: Andreas Spilz , Michael Munz 
Published: December 2024

Abstract
This study presents a novel approach to augment physiotherapeutic exercise datasets by synthesizing realistic Inertial Measurement Unit (IMU) data. The augmented dataset is used to improve the performance of a deep learning based exercise evaluation system. The approach is demonstrated using the deep squat exercise from the Functional Movement Screening (FMS) protocol. By integrating musculoskeletal simulation and leveraging knowledge of potential movement errors based on FMS evaluation criteria, we aim to produce synthetic data that closely mimics human movement. Our evaluation demonstrates that training a combination of a Convolutional Neural Network with a Long-Short-Term-Network (CNN-LSTM) with both real and synthesized data significantly improves the model’s performance, especially in generalizing to unknown subjects. However, limitations such as the approach’s specificity to the deep squat exercise suggest the need for a more adaptable method. Future work will focus on refining the synthesis process to ensure a broader applicability to various exercises. This research contributes to advancing automated physiotherapeutic exercise evaluation, highlighting the importance of synthetic data in achieving better performing and more generalizable models.
Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD)
Authors: Stiehm Michael , Supp Laura , Siewert Stefan , Cherkasov Paul , Reibert Jörg , Forberger Dirk , Schmitz Klaus-Peter 
Published: December 2024

Abstract
Administering fluids and drugs intravenously is crucial in caring for vulnerable patient cohorts such as critically ill patients as well as neonatal and paediatrics patient populations. Studies have revealed severe contamination of infusion solution that could be avoided by utilizing in-line filters. The filtration performance consequently depends on the geometry of the filter housing. The purpose of our numerical study was to analyse the flow situation in filter housings depending on the geometry (diameter of the filter housing and distance between entrance and membrane). We compared the flow of two circular filter system with different housing width (D = 25 mm; L = 1.5 mm/3.0 mm) by means of computational fluid dynamics (CFD). The filter membrane was modelled by a porous jump condition. Both filter systems showed a highly reduced inflow on the membrane compared to the velocity in the Luer Lock ports. The wide filter housing facilitates a more homogenous inflow on the membrane (>92% of the membrane area is applied within a range of 5% of the mean velocity) compared to the narrow filter housing. Despite that difference both filter housings induced a well distributed flow through the filter membrane. However, for large filter systems (>50 mm diameter) the design of the filter housing could play a crucial role in optimising filter performance and therefore CFD should be considered.
The PRIS-Tool. A simple screening device for eye care
Authors: Tautorat Carsten , Grabow Niels , Schmidt Wolfram , Guthoff Rudolf , Stahnke Thomas , Lips Thomas , Senz Volkmar , Lebahn Kerstin 
Published: December 2024

Abstract
With the PRIS-Tool we aim to enable a fast, simple and stable eye self-screening that makes pathological changes in the retinal blood vessels visible to the patient. Furthermore, we envision its application as a quick retinal function test prior to cataract surgeries in low-income regions of the world. Our pocket-sized PRIS-Tool allows for a simplified entoptic testing, due to its integrated light stimulation. PRIS stands for Purkinje Retinal Image Stabilizer. So far, we have built 12 devices in small series and distributed them in our PRIS clinical research network to discuss potential clinical applications. An assisting app will support patients in performing a reliable self-diagnosis and documenting the progress of the disease. Future work will focus on app development and the initiation and evaluation of user studies.
Molecular docking and in vitro evaluation of glucosamine sulfate targeting MMP-3, MMP-9, and IL-4 for potential osteoarthritis treatment
Authors: Srinivasan Venkataramanan , Kunjiappan Selvaraj , Palanisamy Ponnusamy 
Published: December 2024

Abstract

Objectives
This study intended to investigate the potential of glucosamine sulfate (GS) as an inhibitor of genes involved in osteoarthritis (OA) development. Despite GS is often used for OA treatment due to its cartilage preservation and minimum side effects, the molecular mechanism behind its interactions remains unknown.

Methods
Molecular docking was conducted to analyze the interactions between glucosamine sulfate and genes associated with OA such as matrix metalloproteinase-3 (MMP-3), MMP-9, and interleukin-4 (IL-4). Additionally, a cell viability assay using RAW 264.7 cells was performed to evaluate the toxicity of glucosamine sulfate at various concentrations.

Results
Molecular docking results revealed that glucosamine sulfate has a good binding affinity and stable interactions with MMP-3, MMP-9, and IL-4, indicating that it may have inhibitory effects on targeted genes. Nevertheless, the cell viability assay analysis demonstrated that glucosamine sulfate had considerable toxic effects in RAW 264.7 cells at highest concentrations.

Conclusions
Glucosamine sulfate exhibited stable molecular interactions with genes associated to OA development. However, GS toxicity at high concentrations necessitates future research studies to optimize dosing and assess its therapeutic safety in OA treatment.
DAFNE is agile and responsive—a beacon of best practice
Authors: Elliott Jackie , On behalf of the DAFNE Executive Board  
Published: December 2024

The original Dose Adjustment For Normal Eating (DAFNE) randomised controlled trial (RCT) was conducted nearly 25 years ago.1 It has transformed structured education for type 1 diabetes (T1DM) across the UK and is still evolving through its evidence base of further RCTs,2-3 and routine collection of real-world evidence (RWE),4 thereby proving that what works in a research setting, also benefits people with T1DM in the large number (more than half) of the hospital Trusts that have adopted DAFNE countrywide.
This review summarises the latest national audit data, and describes future work responding to the rapid changes in technology used in T1DM, how we are evolving to support people living with type 2 diabetes (T2DM), and adapting our learning materials in the digital age. Through the strength and depth of committed multidisciplinary healthcare professionals (HCPs) we have been able to expand our portfolio of learning materials available to DAFNE centres, who pay a nominal annual fee of ~£5,000. By partnering with the Open University we now offer free accredited online learning to a wide range of HCPs, thereby helping to upskill the diabetes workforce at no extra cost to the NHS.
Finally, in a new and exciting collaboration with the Diabetes Technology Network (DTN) and industry colleagues, DAFNE offers free online training to all people living with T1DM to prepare them for closed-loop therapy.
The CFS Choux Questionnaire
Authors: Newman Lenore 
Published: December 2024

A riff on the well-riffed Proust Questionnaire, the CFS Choux Questionnaire is meant to elicit a tasty and perhaps surprising experience, framed within a seemingly humble exterior. (And yes, some questions have a bit more craquelin than others.) Straightforward on their own, the queries combined start to form a celebratory pyramid of extravagance. How that composite croquembouche is assembled and taken apart, however, is up to the respondents and readers to determine. Respondents are invited to answer as many questions as they choose.
The final question posed—What question would you add to this questionnaire?—prompts each respondent to incorporate their own inquisitive biome into the mix, feeding a forever renewed starter culture for future participants. For this edition, our respondent has replied to a question from Lisa Heldke (CFS Vol. 10 #2).
Our Choux Questionnaire respondent for this issue Lenore Newman. Lenore is the director of the Food and Agriculture Institute at the University of the Fraser Valley, where she holds a Research Chair in Food and Agriculture Innovation. She is a professor in the Faculty of Science at UFV, and is an emeritus member of the Royal Society of Canada's New College.
Hukum Waris di Indonesia Perspektif Hukum Islam dan Hukum Adat
Authors: Haniru Rahmat 
Published: December 2024

This article explains the interrelation between Islamic inheritance law and Indonesian customary inheritance law. Islamic inheritance law is a set of rules that regulates the transfer of property from a deceased to the rightful heirs. It means that the law determines who the heirs are and who are not. It also determine the potion or percentage of each heir of the property. Similarly, customary inheritance law regulates the transfer of property and other property-related rights. The comparison between the two laws results in several similar features despite their differences. In customary inheritance law, some property may not be distributed among heirs or their distribution may be deferred to a later time, while in Islamic inheritance law, each inheritor is entitled to request his or her share of inheritance at any time. In customary law, adopted children may become inheritor if the deceased decided to do so, while Islamic inheritance law adopted children doesÂ not have this regulation. In addition, the share of each inheritor is not predetermined in customary law, while Islamic inheritance law determines the share of each inheritor which cannot be negotiated.
[Hukum waris Islam adalah aturan yang mengatur pengalihan harta dari seseorang yang meninggal dunia kepada ahli warisnya. Hal ini berarti menentukan siapa-siapa yang menjadi ahli waris, porsi bagian masing-masing ahli waris, menentukan bagian harta peninggalan dan harta warisan yang diberikan kepada ahli waris. Hukum waris adat adalah serangkaian peraturan yang mengatur penerusan dan pengoperan harta peninggalan atau harta warisan dari suatu generasi ke generasi lain, baik yang berkaitan dengan harta benda maupun yang berkaitan dengan hak-hak kebendaan. Perbandingan antara hukum waris islam dan hukum waris adat, diantaranya: a. Dalam hukum waris adat, harta peninggalan dapat bersifat tidak dapat dibagi-bagi atau pelaksanaan pembagiannya ditunda. Sedangkan dalan hukum waris Islam, tiap ahli waris dapat menuntut pembagian harta peninggalan tersebut sewaktu-waktu. b. Hukum waris adat memberi kepada anak angkat, hak nafkah dari harta peninggalan orang tua angkatnya. Sedangkan dalam hukum waris Islam, tida ada ketentuan ini. c. Dalam hukum waris adat, pembagiannya merupakan tindakan bersama, berjalan secara rukun dengan memperhatikan keadaan khusus tiap waris. Adapun dalam hukum waris Islam, bagian-bagian para ahli waris telah ditentukan.]
Comparison of canine retraction in maxillary arch using self-ligating brackets and conventional brackets: An in vivo study
Authors: Jain Parul , Bali Govina , Singla Suchinder Kumar , Sharma Abhishek , Jindal Atul 
Published: December 2024

: In sliding mechanics, a considerable amount of applied force is lost to frictional resistance which places undue stress on the anchor unit. Therefore, for a clinical success with maximal efficiency for canine retraction with sliding mechanics, reduction of the resistance due to friction between brackets and arch wires is important. Self-ligating brackets are claimed to reduce the sliding resistance.: Aim of the study was to compare the clinical outcome of canine retraction using Self ligating brackets and Conventional Brackets during canine retraction. Objectives of the study were to compare the amount of canine retraction using Self ligating brackets and Conventional Brackets and to compare the amount of anchorage loss during canine retraction (CR) using Self ligating brackets and Conventional Brackets.: The study comprised a total of 20 patients aged between 13 and 22 years. Bilateral extraction of the first premolars in maxilla and separate canine retraction was done. A split mouth study design was conducted in which maxillary canines randomly bonded with self-ligating and conventional brackets. Study models were used for the measurement of canine retraction, anchorage loss and canine rotation. Statistical analysis was done. Self-ligating and conventional brackets produced similar amount of canine retraction and anchorage loss of the maxillary molars. Self-ligating brackets gave better rotation control of maxillary canines than conventional brackets. Self-ligating and conventional brackets gave similar results for the amount of canine retraction and anchorage loss. Self-ligating brackets give better rotational control.
Using UX Testing to Optimize Discoverability of Non-traditional Resources
Authors: Campbell Lucy , Jeffery Keven 
Published: December 2024

Objective – The accessibility of non-traditional resources presents ongoing challenges for users and librarians. This study investigates methods for optimizing metadata and the placement of search results to enhance the discoverability of these resources within library systems. Researchers conducted A/B testing to compare two features of Ex Libris Primo: the Resource Recommender and Discovery Import Profiles. The objective was to enhance user access to a broader range of informational assets beyond conventional collections. This study posed the research question: Is inclusion in the results list (Discovery Import Profiles) or are visually appealing advertisement-style cards above results (Resource Recommender) a more effective method for discovery of non-traditional library resources?
Methods – Researchers identified four key resource types for testing: librarians, frequently asked questions (FAQs), databases, and research guides. An A/B test was conducted with each resource presented in the Discovery Import Profiles and Resource Recommender formats. Following the A/B test, a combined C test was conducted to validate findings.
Results – The ad-style cards achieved higher engagement rates, particularly for databases and FAQs, while research guides performed better when embedded directly in search results. This study highlights the strengths and limitations of each method. Databases and FAQs benefited from the visual prominence of the ad-style cards, while research guides were more discoverable within search results. However, minimal engagement with librarians as a resource type across both methods suggests the need for improved tagging and metadata strategies.
Conclusion – Findings underscore the importance of institution-specific research and localized assessments to ensure effective implementation of discovery strategies. This study provides a useful method for libraries aiming to enhance the discoverability of their non-traditional resources, ultimately improving user access and satisfaction.
Do sentimento de piedade à possibilidade de outras configurações sociais e políticas
Authors: Reis Helena Esser dos 
Published: December 2024

Apesar do modo como se dá a passagem do homem natural ao homem social não ser objeto de uma investigação detalhada por parte de Rousseau, posto que afirma decorrer de acasos fortuitos, as consequências desta passagem não são desprezíveis. A longa descrição deste processo no Segundo Discurso nos faz compreender que a desnaturação tende a resultar em vícios e violações; entretanto, percorrendo as obras de Rousseau encontramos argumentos para pensar que aquela história verossímil não condena a humanidade. Nosso propósito, neste artigo, será investigar neste primeiro movimento de saída da própria individualidade a possibilidade de uma socialização baseada na virtude e no compromisso com o outro. A dificuldade deste projeto decorre de seus próprios pressupostos – os acasos fortuitos que levam as pessoas a se encontrarem e conviverem não as prepara para esta nova etapa. O convívio desperta paixões que sufocam, embora não aniquilem, o sentimento original de piedade. Discutiremos, então, sobre a possibilidade de estimular este sentimento, a fim de favorecer um processo de socialização que reconheça o outro como igual e estabeleça compromissos mútuos entre as pessoas no âmbito da vida social e política.
RELATIONSHIP OF SERVICE RECOVERY TOWARDS PATIENT SATISFACTION IN HOSPITAL IN WEST SUMATERA
Authors: Semiarty Rima , Machmud Rizanda , Abdiana  , Wahyuni Annisa , Hamzah Prima Kurniati 
Published: December 2024

Background: Patient satisfaction in the M. Djamil Hospital was recorded as 79.61% between January and March 2018. It signifies that patient satisfaction rate has not met the target set of 85%.
Aims: This study aims to determine the frequency distribution of service recovery patients, patient satisfaction, and the relationship between services and service recovery patient satisfaction to improve service recovery.
Methods: The authors used a cross-sectional research design. The sample was inpatients at RSUP M. Djamil in total of 424 people. The sampling technique was consecutive sampling. The data were collected using the Importance Performance Analysis questionnaire. Data were analyzed using unpaired t-tests and multiple linear regression.
Results: The results of the service recovery (distributive justice, procedure justice, interactive justice, reputation justice) has a significant relationship (p-value <0.05) with patient satisfaction. Interactive justice has the strongest relationship with appropriate patient satisfaction and has the greatest Beta value (0,254). Patient satisfaction has a significant relationship (p-value <0.05) with Word of Mouth.
Conclusion: RSUP M. Djamil needs to emphasize interactions and justice, especially in providing clear information about medical actions to the patient's family, serving patients politely and friendly, and providing solutions to patients if there are service complaints.
Keywords: Hospitalization, Satisfaction, Service Recovery
ANALYSIS OF PUBLIC SAFETY CENTER 119 AMBULANCE SERVICES USING LEAN SIX SIGMA
Authors: Rojak Thasya Sabilla Putri , Basabih Masyitoh , Winarto  , Suranta Roy Michael 
Published: December 2024

Background: DKI Jakarta reports about 5,000 annual deaths from heart disease, disasters, accidents, and other causes. Ambulance demand has risen, especially for COVID-19 cases that require quick medical attention. In 2022, the average emergency response time was 21-30 minutes. Therefore, efforts are needed to improve the response time of PSC 119 ambulances to minimize impacts.
Aims: This study uses the Lean Six Sigma methodology to analyze the factors contributing to prolonged response times in emergency ambulance services.
Methods: This study used a mixed-method approach based on the DMAI (define, measure, analyze, and improve). The data were collected through observations, document reviews, and in-depth interviews.
Results: The results showed that the average duration of ambulance services was 4 hours and 30 minutes. The identified inefficiencies include software issues with the Nusantara app, staff fatigue, and license renewals, difficult access for ambulance and URC units, delays from call center staff awaiting family decisions, closely located posts leading to fewer cases per post, community-initiated patient movements, challenges in finding suitable referral hospitals for special cases, and slow response times from referral hospitals.
Conclusion: The recommended improvements include using a kaizen board, conducting expert training, promoting the Integrated Referral System or Sistem Informasi Rujukan Terintegrasi (SISRUTE), and revising standard operating procedures.
Keywords: ambulance services, Public Safety Center 119, Lean Six Sigma
AN EXAMINATION OF THE IMPLEMENTATION OF INTERNET OF THINGS IN HEALTHCARE UTILIZING SMARTWATCHES
Authors: Boshrabadi Fatemeh Sadeghi , Abolhassani Moussa , Shafaghi Shadi , Ghorbani Fariba , Shafaghi Masoud 
Published: December 2024

Background: Smartwatches can use sensors to collect and send data to medical teams and family members through the platform of the Internet of things (IoT). The data are first analysed on the platform and the final results are used by the medical team.
Aims: This paper reviews and categorises studies conducted in the field of the Internet of things based on smartwatches.
Methods: The covered papers have been published over 13 years from 2010 to 2022. The search yielded 227 papers out of which 43 papers were reviewed after screening. The search keywords were “wearables, internet of things, smartwatches, smart bracelet, healthcare, and disease”. The search covered databases including PubMed, ScienceDirect, and IEEE.
Results: Smartwatches are used in three fields of healthcare, including palliative care, speech therapy, diagnosis, disease prevention, rehabilitation, and health improvement.
Conclusion: Smartwatches are not free of drawbacks and have not received the attention they deserve in the healthcare field. Given the potential of smartwatches, they can be useful in the health sector.
Keywords: Disease, IOT, Smartwatch, Wearable
Growth performance indices and internal organ characteristics of male pigs fed diets containing Aspilia africana leaf meal
Authors: Iwuji Tobechukwu Chijioke , Cynthia Okafor Amarachi , Innocent Ejiofor , Uchenna Ahiwe Emmanuel , Chinyere Egenuka Francisca , Evangeline Kadurumba Ogechi , Adanna Peter-Onoh Chidinma , Somtochukwu Ebumnonu Marycynthia 
Published: December 2024

Abstract

The high cost of feedstuff and untoward effects of synthetic drug use in livestock production necessitated this research, which evaluated the roles of Aspilia africana leaf meal (AALM) on the growth and organ characteristics of pigs. Fifty (50) growing large white male pigs of 10–12 weeks old with average weight of 10.93kg were used. The pigs were grouped into five, having five replicates of two pigs each. Each group was assigned to an experimental diet in a completely randomized design. The diets were the control diet (without AALM); the AALM2.5 diet containing 2.5% AALM; the AALM5.0 diet containing 5.0% AALM; the AALM7.5 diet containing 7.5% AALM; and the AALM10.0 diet containing 10.0% AALM. Feed intake (FI) and body weight gain (BWG) decreased (p < 0.05) with increasing levels of AALM, while feed conversion ratio (FCR) was best (p < 0.05) with AALM5.0 diet. The percentage weight (PW) of the lungs, intestine, and testes was higher (p < 0.05) in AALM5.0 and AALM7.5 than in other treatments which were similar (p > 0.05), while the PW of the liver increased (p < 0.05) with increasing levels of AALM. Pigs on AALM10.0 diet recorded non-pathological changes in their lungs, liver, and kidney. Proliferation of sperm cells under normal tissue architecture was observed in the testes of AALM5.0, AALM7.5, and AALM10.0 pigs. The aim of the present study was to evaluate the role of a non-conventional feed resource, Aspilia africana leaf meal (AALM) on the growth and internal organ characteristics of male pigs.