bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trends and sex disparities in school bullying victimization among U.S. youth, 2011–2017
Authors: Li Ruili , Lian Qiguo , Su Qiru , Li Luhai , Xie Meixian , Hu Jun 
Published: May 2020

Abstract
Objectives The prevalence of being bullied traditionally among U.S. high school students is expected to reduce to 17.9%, according to Healthy People 2020 Initiatives. We examined trends in traditional and cyberbullying victimization with the latest large-scale time-series data in the United States. Methods We analyzed the data from the 2011-2017 national Youth Risk Behavior Survey (YRBS) to access the trends in traditional and cyberbullying among U.S. high school students. We identified the temporal trends using multivariate logistic regression analyses, accounting for survey design features of YRBS. Results The overall prevalence of victimization was 19.74% for traditional bullying and 15.38% for cyberbullying, suggesting that cyberbullying is not a low frequent phenomenon. The prevalence of victimization ranged from 20.19% to 19.04% for traditional bullying and 16.23% to 14.77% for cyberbullying, and the declined trends for the two kinds of bullying victimization were both statistically non-significant. The degree of overlap between the two kinds of bullying victimization was about 60%. Besides, female students experienced more traditional and cyberbullying than male peers within each survey cycle. Conclusions No declined trends in traditional and cyberbullying victimization were observed during 2011-2017. Female students are more likely to experience bullying. To achieve the Healthy People 2020 goal on bullying, more work is needed.
Aboriginal Community Controlled Health Organisations address health equity through action on the social determinants of health of Aboriginal and Torres Strait Islander peoples in Australia.
Authors: Pearson Odette , Schwartzkopff Kate , Dawson Anna , Hagger Christina , Karagi Agape , Davy Carol , Brown Alex , Braunack-Mayer Annette 
Published: May 2020

Abstract
Background Indigenous populations globally are continually striving for better health and wellbeing due to experiencing significant health and social inequities. The social determinants of health are important contributors to health outcomes. Comprehensive primary health care that is governed and delivered by Indigenous people extends beyond the biomedical model of care to address the social determinants of health. Aboriginal Community Controlled Health Organisations (ACCHOs) are known to provide culturally informed, holistic health services that directly and indirectly address the social determinants of health. The range and extent of their activities in addressing the social determinants of health, however, is not well documented.Methods The most recent ACCHO annual reports were retrieved online or by direct correspondence. For coding consistency, a dictionary informed by the World Health Organization’s Conceptual Framework for Action on the Social Determinants of Health was developed. A document and textual analysis of reports coded ACCHO activities and the determinants of health they addressed, including intermediary determinants, socio-economic position and/or socio-political context. Summary statistics were reported. Representative quotes illustrating the unique nature of ACCHO service provision in addressing the social determinants of health were used to contextualise the quantitative findings.Results Sixty-seven annual reports were collected between 2017 and 2018. Programs were delivered to population groups across the life span. Fifty three percent of reports identified programs that included work at the socio-political level and all annual reports described working to improve socioeconomic position and intermediary determinants of health through their activities. Culture had a strong presence in program delivery and building social cohesion and social capital emerged as themes.Conclusions This study provides evidence of the considerable efforts of the ACCHO sector, as a primary health care provider, in addressing the social determinants of health and health inequity experienced by Indigenous communities. For the Aboriginal and Torres Strait Islander population, ACCHOs not only have an essential role in addressing immediate healthcare needs but also invest in driving change in the more entrenched structural determinants of health. These are important actions that are likely to have an accumulative positive effect in closing the gap towards health equity.
Physiological and transcriptome analysis of Poa pratensis var. anceps cv. Qinghai in response to cold stress
Authors: Dong Wenke , Ma Xiang , Jiang Hanyu , Zhao Chunxu , Ma Huiling 
Published: May 2020

Abstract
Background
Low temperature limits the growth and geographical distribution of plants. Poa pratensis is a cool-season turfgrass mainly grown in urban areas. However, low winter temperature or cold events in spring and autumn may cause P.pratensis mortality, affecting the appearance of lawns. P.pratensis var. anceps cv. Qinghai (PQ) is widely distributed in the Qinghai-Tibet Plateau above 3000 m. PQ has greater cold resistance than the commercially cultivated P.pratensis varieties. However, existing studies on the response mechanism of PQ to low temperatures have mainly focused on physiological and biochemical perspectives, while changes in the PQ transcriptome during the response to cold stress have not been reported.
Results
To investigate the molecular mechanism of the PQ cold response and identify genes to improve the low-temperature resistance of P.pratensis, we analyzed and compared the transcriptomes of PQ and the cold-sensitive P.pratensis cv. ‘Baron’ (PB) under cold stress using RNA sequencing. We identified 4878 and 1871 differentially expressed genes (DEGs) between the treatment vs control comparison of PQ and PB, respectively, with 4494 DEGs specific to PQ. Based on the DEGs, important Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, such as “starch and sucrose metabolism”, “protein processing in endoplasmic reticulum”, “phenylalanine metabolism” and “glycolysis/gluconeogenesis” were significantly enriched in PQ, and “starch and sucrose metabolism”, “phenylpropanoid biosynthesis”, “galactose metabolism” and “glutathione metabolism” were significantly enriched in PB. In addition, the “glycolysis” and “citrate cycle (TCA cycle)” pathways were identified as involved in cold resistance of P.pratensis.
Conclusions
As we know, this is the first study to explore the transcriptome of P.pratensis var. anceps cv. Qinghai. Our study not noly provides important insights into the molecular mechanisms of P.pratensis var. anceps cv. Qinghai responds to cold stress, but also systematically reveals the changes of key genes and products of glycolysis and TCA cycle in response to cold stress, which is conductive to the breeding of cold-resistant P.pratensis genotype.
One-step percutaneous transhepatic cholangioscopy combined with high-frequency needle-knife electrotomy in biliary strictures after liver transplantation
Authors: Tao Haisu , Wang Ping , Sun Beiwang , Zhou Xinghua , Xie Jiafen 
Published: May 2020

Abstract
Background
Endoscopic management is the mainstay for biliary strictures after liver transplantation. However, this method is often failed in cases associated with hepatolithiasis or refractory strictures. The aim of this study is to investigate whether one-step PTC combined with high-frequency needle-knife electrotomy can be an alternative method in biliary strictures after liver transplantation that could not be treated by endoscopic management.
Methods
Clinical data of 14 patients suffering from biliary strictures after liver transplantation from June 2014 to January 2018 were retrospectively analyzed. One-step PTC combined with high-frequency needle-knife electrotomy was used to resolve the strictures.
Results
One-step PTC was successfully performed in all 14 patients. In 10 of 12 (83.3%) patients with hepatolithiasis, the stones were removed completely. The stricture resolution was achieved in 13 of 14 (92.9%) patients at supporting catheter removal. Three mild adverse events occurred (cholangitis, 2 patient; delayed hemobilia, 1 patient), but were resolved with conservative treatment. The follow up after supporting catheter removal was 15.7 ± 4.5 months. Only 1 patient (8.3%) had stone recurrence and no stenosis occurred during supporting-free follow-up.
Conclusion
One-step PTC combined with high-frequency needle-knife electrotomy appears to be a useful for treating biliary strictures after liver transplantation.
Association mapping of Iranian wheat genotypes to detect QTLs conferring resistance to stem rust at seedling stage
Authors: Saremirad Ali , Bihamta Mohammad , Malihipour Ali , Mostafavi Khodadad , Alipour Hadi 
Published: May 2020

Abstract
Background

Stem rust caused by Puccinia graminis f. sp. tritici (Pgt) is an important disease of wheat in the world. Pgt pathogen is constantly evolving and creating more virulent races that break down stem rust (Sr) resistance genes. As a result, many of Sr genes have become ineffective against new Pgt races. Exploring new sources of resistance to detect new Sr genes/QTLs is very important in order to introducing them into wheat breeding programs and developing resistant wheat cultivars. The objective of the present study was to evaluate 297 Iranian wheat genotypes for resistance to stem rust at seedling stage and to detect Sr resistance genes/QTLs through association mapping (AM).
Results

A set of 297 Iran bread wheat cultivars and landraces were evaluated for infection type and latent period in four race of Pgt. Genotypic data of 282 genotypes were available, so AM was performed based on 282 genotypes. The results of population structure analysis showed that 277 genotypes clearly were distinguished in the three subpopulations and the other five genotypes were classified in the mixed group. The mean linkage disequilibrium decreased with increasing genetic distance. The markers did not have a uniform distribution on the genomes, so the share of each of the A, B and D genomes in commercial cultivars and landraces was approximately 37, 46 and 17%, respectively. Collectively, 69 QTLs for infection type and 62 QTLs for latent period of studied Pgt races were identified in the original dataset (P ≤ 0.001). In the imputed SNPs dataset, the number of QTLs for infection type increased to 504 QTL and for latent period increased to 454 QTLs (P ≤ 0.001).
Conclusion

Based on the results of this study, it can be concluded that the Iranian wheat genotypes are valuable source resistance to stem rust. By incorporating these genotypes into wheat breeding programs and optimizing effective resistance genes, an important step can be taken to prevent the threat of and the disease to ensure food security. This study provides additional useful information for selection of resistant genotypes against the disease by improving marker-assisted selection efficiency.
Literature Analysis of Blastocystis sp. from 1990 to 2019 in China
Authors: Ning Chao-qun , Ai Lin , Tian Li-Guang 
Published: May 2020

Abstract
Background
Blastocystis sp. is ubiquitous presence in animals and humans worldwide and a broad diversity genetically. The aim of this study was to find out the main research progress and research status of Blastocystis sp. in China in the past thirty years.
Methods
On the Chinese mainstream database China National Knowledge Infrastructure (CNKI), Wanfang database and PubMed database, the research literatures of Chinese Blastocystis sp. were searched and analyzed.
Results
285 articles related to Blastocystis sp. were retrieved, including 244 published in Chinese and 41 English on pathogen morphology, epidemiological investigation, laboratory detection and diagnosis, clinical case reports, drug treatment, animal model establishment as well as pathogenicity studies. There were the most epidemiological investigations and researches on pathogenic morphology decreasing recently Surveys of Blastocystis sp. of human has been carried out among a total of 18 provinces, with infection rates ranging from 0.007–48.6%. Infants and young children, school students, hospitalized diarrhea patients, human immunodeficiency virus (HIV) patients, tuberculosis patients, and cancer patients as respondents had been included. ST1-ST7 and ST12 were the main subtypes in Chinese population. Moreover, surveys of Blastocystis sp. of animal were also conducted in 12 provinces, with infection rates ranging from 2.54–79.41%. A variety of animals were investigated including pigs, cattle, sheep, yak, giant panda, and Crested Ibis et al., with the main subtypes of ST1-ST8, ST10, ST12-ST14. In vitro culture and Polymerase chain reaction (PCR) were commonly used to detect Blastocystis sp. in research and less in clinical application. Traditional Chinese medicine and western medicine for clinical drug treatment appeared curative effects. However, there were few reports on the application of traditional Chinese medicine in clinical treatment. The pathogenicity of Blastocystis sp. remains controversial and needs further exploration.
Conclusion
various researches on Blastocystis sp. had been carried out in China, especially in epidemiology. However, there is no report on the relationship between human Blastocystis sp. and animal infection. Furthermore, the relationship between infant diarrhea and its impact on the intestinal microecology have not received much attention from clinicians. The research on Blastocystis sp. still needs to be strengthened to provide effective data for the prevention and control and improve the quality of life of the population.
Design and validation of Brucellosis prevention questionnaire focused on animal vaccination
Authors: Ghofranipour Fazlollah , Bahadori Farhad , Ghaﬀarifar Saeideh , Ziaei Reza 
Published: May 2020

Abstract
Background Animal breeders' inadequate awareness about the transmission of brucellosis and their improper knowledge about prevention of brucellosis are among important barriers to vaccinate animals against brucellosis. The aim of this study is design, implementation and evaluation of a theory-driven and vaccination-focused training program for brucellosis prevention.Methods In this exploratory psychometric study, a brucellosis prevention questionnaire (BPQ) was developed. Face-to-face interviews were conducted to develop the initial items of BPQ. The findings from interviews were merged with those of literature review. Face, content and construct validity of BPQ were assessed by participation of animal breeders, veterinarians and health educationists. Impact Score (IS), Content Validity Ratio (CVR) and Content Validity Index (CVI) of the items were calculated. Construct validity of BPQ was evaluated through factor analyses. Cronbach’s alpha, Intra-class correlation coefficient (ICC), composite reliability and standard error of measurement (SEM) were measured to assess the reliability of the findings by BPQ.Results BPQ was finalized by 53 items. Its validity was confirmed by CVI, CVR, and IS of 0.90, 0.74 and 4.30, respectively. The items were loaded into three constructs of awareness, attitude and practice. The predictive power of the awareness, attitude and practice was 43.43%, 15.81% and 15.78%, respectively. The fitness of the proposed model among those constructs was confirmed by RMSEA < 0.08, Normed Chi2 < 5, CFI > .90, TLI > .90.Conclusion The brucellosis prevention questionnaire has acceptable psychometric properties. Applying BPQ, veterinarians and educational planners can identify factors influencing animal breeders' preventive behavior.
Trends of alcohol use, dietary behaviour, interpersonal violence, mental health, oral and hand hygiene behaviour among adolescents in Lebanon: cross-sectional national school surveys from 2005, 2011 and 2017
Authors: Pengpid Pengpid , Peltzer Karl 
Published: May 2020

Abstract

Background This investigation aimed to report the trends in the prevalence of various health risk behaviours among adolescents in Lebanon.Methods Cross-sectional nationally representative data were analysed from 13,109 adolescents (14 years median age) that participated in three waves (2005, 2011 and 2017) of the “Lebanon Global School-Based Student Health Survey (GSHS)”.Results Significant improvements were found among both boys and girls in the decline of interpersonal violence (bulling victimization, being physically attack and involvement in physical fighting), poor washing of hands after using the toilet, and among girls only suicidal ideation and suicide plan. Significant increases were found among both boys and girls in the prevalence of inadequate fruit consumption, unintentional injury and among boys only poor washing of hands prior to eating and among girls only having no close friends and school truancy.Conclusion Several decreases but also increases of health risk behaviours were found over three assessment points during a period of 12 years calling for continued health enhancing activities in this adolescent population.
Level and Determinants of Willingness to Donate Organs Among the General Public: A Cross-Sectional Survey in China
Authors: Fan Xiaojing , Zheng Sirui , Li Meng , Wang Duolao , Li Enchang , Zhou Zhongliang , Zheng Weirong , Wang Lingling , Zhang Qing , Li Yingying , Lin Jianfeng 
Published: May 2020

Abstract
Background: This study aims to assess the level and determinants of the general public’s willingness to organ donation. Methods: We conducted a population-based cross-sectional study of 4261 participants in China. The primary outcome was the willingness to donate organs. Logistic regression modelling was used to determine the factors that affect willingness to donate organs. Results: Overall, the proportion of participants who showed a willingness to donate organs was 47.45% (95%CI: 0.46, 0.49) in this study. Logistic regression modelling showed participants from Western (OR=1.35, 95%CI=1.13-1.62) and Eastern China (OR=1.54, 95%CI=1.20-1.66) were more willing to donate organs compared with those from Central China. The odds of being willing to donate organs was higher in females than males (OR=1.34, 95%CI=1.17-1.55); and was higher in those participants with experience of organ donation (OR=1.57, 95%CI=1.12-2.20), experience of caring for organ transplant patients (OR=1.47, 95%CI=1.03-2.10), and those undertaking related voluntary activities (OR=1.68, 95%CI=1.45-1.94), than those without. Conclusion: The general public’s level of willingness to organ donation was not high in China. Geographical region, gender, experience of organ donation related activities, taking care of organ transplant patients and volunteering in related activities were independently associated with participants’ willingness to donate organs.
Genome-wide association study for yield and yield related traits under reproductive stage drought in a diverse indica-aus rice panel
Authors: Bhandari Aditi , Sandhu Nitika , Bartholome Jérôme , Cao-Hamadoun Tuong-Vi , Ahmadi Nourollah , Kumari Nilima , Kumar Arvind 
Published: May 2020

Abstract
Background Reproductive-stage drought stress is a major impediment to rice production in rainfed areas. Conventional and marker-assisted breeding strategies for developing drought-tolerant rice varieties are being optimized by mining and exploiting adaptive traits, genetic diversity; identifying the alleles, and understanding their interactions with genetic backgrounds for their increased contribution to drought tolerance. Field experiments were conducted in this study to identify marker-trait associations (MTAs) involved in response to yield under reproductive-stage (RS) drought. A diverse set of 280 indica-aus accessions was phenotyped for grain yield and nine yield-related traits under normal irrigated condition and under two managed reproductive-stage drought environments. The accessions were genotyped with 215,250 single nucleotide polymorphism markers. Results The study identified a total of 220 significant MTAs for 10 traits and candidate gene analysis within a 200kb window centered from GWAS identified SNP peaks detected these MTAs within/ in close proximity to 38 genes, 4 earlier reported major grain yield QTLs and 6 novel QTLs for 7 traits out of the 10. The significant MTAs were mainly located on chromosomes 1, 2, 5, 6, 9, 11 and 12 and the percent phenotypic variance captured for these traits ranged from 5 to 88%. The significant positive correlation of grain yield with yield-related traits, except flowering time, observed under different environments point towards their contribution in improving rice yield under drought. Seven promising accessions were identified for use in future genomics-assisted breeding programs targeting grain yield improvement under drought. Conclusion These results provide a promising insight into the complex genetic architecture of grain yield under reproductive-stage drought in different environments. Validation of major genomic regions reported in the study will enable their effectiveness to develop drought-tolerant varieties following marker-assisted selection as well as to identify genes and understanding the associated physiological mechanisms.
Comparisons of chest computed tomography patterns between survivors and non-survivors with Coronavirus Disease 2019 (COVID-19): a case-control study
Authors: Pan Feng , Zheng Chuansheng , Ye Tianhe , Li Lingli , Liu Dehan , Li Lin , Hesketh Richard L. , Yang Lian 
Published: May 2020

Abstract
Objectives To compare the chest computed tomography (CT) findings between survivors and non-survivors with Coronavirus Disease 2019 (COVID-19).Materials and Methods Between 12 January 2020 to 20 February 2020, the records of 124 consecutive patients diagnosed with COVID-19 were retrospectively reviewed and divided into survivor (83/124) and non-survivor (41/124) groups. Chest CT findings were qualitatively compared on admission and serial chest CT scans were semi-quantitively evaluated between two groups using curve estimations.Results Elder age (median: 69 vs. 43y, p<0.001), higher male ratio (31/41 vs. 32/83, p<0.001), and more comorbidities were observed in non-survivor group. On admission, significantly more bilateral (97.6% vs. 73.5%, p=0.005) and diffuse lesions (39.0% vs. 8.4%, p<0.001) with higher total CT score (median: 10 vs. 4) were observed in non-survivor group compared with survivor group. Besides, crazy-paving pattern was more predominant in non- survivor group than survivor group (39.0% vs. 12.0%, p=0.004). From the prediction of curve estimation, in survivor group total CT score increased in the first 20 days reaching the peak of 6 points and then gradual decreased for more than other 40 days (R2=0.545, p<0.001). In non- survivor group, total CT score rapidly increased over 10 points in the first 10 days and gradually increased afterwards until ARDS occurred with following death events (R2=0.711, p<0.001).Conclusions Persistent progression with predominant crazy-paving pattern was the major manifestation of COVID-19 in non-survivors. Understanding this CT feature could help the clinical physician to predict the prognosis of the patients.