bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary Breast Angiosarcoma: Utilisation of Pre-surgical Magnetic Resonance Imaging (MRI) for Accurate Tumour Characterization and Planning – A Case Report and Literature Review
Authors: Mumin Nazimah Ab , Rahmat Kartini , Hamid Marlina Tanty Ramli , Ng Wei Lin , Chan Wai Yee , Cheah Xin Ying , See Mee Hoong , Yip Cheng Har 
Published: October 2020

Background:
Primary breast angiosarcoma is a rare malignancy with non-specific clinical
and radiological findings.

Case Report:
A 30-year-old lady presented with left breast pain and lumpiness for over one year.
She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently,
in view of the rapid growth of the lump and worsening pain, she was re-investigated with
US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma.
The diagnosis was confirmed after biopsy and she underwent mastectomy.

Discussion:
Literature review on imaging findings of breast angiosarcoma, especially on MRI, is
discussed. MRI features showed heterogeneous low signal intensity on T1 and high signal intensity
on T2. Dynamic contrast enhancement (DCE) features included either early enhancement with or
without washout in the delayed phase, and some reported central areas of non-enhancement.

Conclusion:
This case report emphasises on the importance of MRI in clinching the diagnosis of
breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay.
Bandwidth Modelling on Geographically Weighted Regression with Bisquare Adaptive Method using Kriging Interpolation for Land Price Estimation Model
Authors: Handayani Alfita Puspa , Deliar Albertus , Sumarto Irawan , Syabri Ibnu 
Published: October 2020

Land prices, especially in an urban area, are dynamically changing. To be able to do an evaluation, the right models must have the ability to understand land price characteristics that also dynamically changing. Every land price must attach to a location (spatial based). One of the locations (spatial based) models is Geographically Weighted Regression (GWR). This model can provide a local model based on the concept of attachment between observation and regression points. The main component is the determination of Optimum Bandwidth, which will determine the accuracy of the final GWR model. In the bandwidth process, it is necessary to do trial and error to get the Optimum Bandwidth value. Cross-Validation method commonly used to determine optimum bandwidth on observation point, but this study aims to minimize the process of trial and error in determining optimal bandwidth outside the observation point by using kriging interpolation. The Kriging method can substantially provide better bandwidth usage without having to do a trial process with too many errors.
Tidal Swamps Development in West Kalimantan: Farmers Prefer A Rational-Moderately Strategy
Authors: Sudrajat Jajat , Gafur Sutarman , Gafur Sutarman , Gafur Sutarman 
Published: October 2020

The Indonesian government has spent lots of budgets and built more infrastructures to escalate the intensive rice farming in the tidal swamps since 1970s. However, the success story is very limited. This study aims to describe some obstacles in the practice of rice intensification, and also to explain some factors leading to their failure. In explaining this context, we refer them to our-own-experiences in tidal lowlands development project from 2008 to 2009, literatures study, and then it is deepened by doing collectives case study –that is consisting of three studies in the type of-B, C, and D overflows. The local farmers used to reject the intensive rice farming practices. The use of local paddy varieties is a prefer strategy option. It is closely related to minimize the farming cost and also as a strategy so that they have more time to manage another farm activities. Rationally the farmers prefer growing a variety of perrenial crop species that suits their personal needs and strategies. In conclusion, this study showed that agro-ecological based farm could be the most adaptive way in optimizing the indigenous rice farming.
US cost–effectiveness of polatuzumab vedotin, bendamustine and rituximab in diffuse large B-cell lymphoma
Authors: Betts Keith A , Thuresson Per-Olof , Felizzi Federico , Du Ella X , Dieye Ibou , Li Jia , Schulz Mathias , Masaquel Anthony S 
Published: October 2020

Aim:
To evaluate the cost–effectiveness of polatuzumab vedotin (pola) + bendamustine + rituximab (BR) in relapsed/refractory diffuse large B-cell lymphoma based on the GO29365 trial from a US payer’s perspective.
Materials & methods:
A partitioned survival model used progression-free survival and overall survival data from the GO29365 trial. The base case analysis assumed overall survival was informed by progression-free survival; a mixture cure model estimated proportion of long-term survivors.
Results:
In the base case, pola + BR was cost-effective versus BR at US$35,864 per quality-adjusted life year gained. Probabilistic and one-way sensitivity analyses showed that the findings were robust.
Conclusion:
Pola + BR is cost-effective versus BR for the treatment of transplant-ineligible relapsed/refractory diffuse large B-cell lymphoma in the US.
Addition of an anti-staphylococcal beta lactam to standard antibiotic therapy does not decrease 90-day mortality of MRSA bacteremia versus standard therapy alone
Authors: Hessler Monica 
Published: October 2020

A clinical decision report appraising
Tong SYC, Lye DC, Yahav D, et al. Effect of vancomycin or daptomycin with vs without an antistaphylococcal β-lactam on mortality, bacteremia, relapse, or treatment failure in patients with MRSA bacteremia: a randomized clinical trial. JAMA. 2020;323(6):527–537. https://doi.org/10.1001/jama.2020.0103
for a patient with multiple comorbidities including heart failure, severe aortic regurgitation, aortic aneurysm and intellectual disability being treated for MRSA bacteremia who is intubated in the ICU.
Sustainable Higher Education as a Challenge for Latvia: Impact of the Constitutional Court of the Republic of Latvia
Authors: Rodiņa Anita 
Published: October 2020

In view of the current relevance of the concept of sustainability, the article examines the application of this principle within the system of higher education in three essential areas, analysing the existing situation and outlining the necessary improvements in the context of sustainability. The article also reveals the impact of the rulings delivered by the Constitutional Court of the Republic of Latvia on the sustainable development of institutions of higher education, highlighting the rulings, which directly deal with issues important for institutions of higher education, inter alia, in the context of the development of the rule-of-law state. The author also expresses her opinions on the need for a dialogue between the legislator and the Constitutional Court on these matters, as well as urges to seek solutions to several essential issues regulating the life of institutions of higher education – both with respect to regulation on the employment legal relationship and the criteria set for the Latvian Science Council’s expert in the legal science.
Problematics of Identification of a Continuous Criminal Offence
Authors: Liholaja Valentija , Hamkova Diāna 
Published: October 2020

The publication focuses on the issue of the substance of a continuous criminal offence and its features to draw a line of demarcation between a continuous criminal offence as a type of separate (unitary) criminal offence and the real concurrence of several independent criminal offences, which is required for the correct qualification of criminal offences. In searching for an answer to this, the criminal law regulation has been analysed, findings of the criminal law theory and judicature have been studied, the practice of applying the norms of criminal law in criminal cases of various categories, in providing the legal qualification of criminal offences, has been compiled.
Risk Factors Associated With Cerebro-Vascular Accident Ischemic Stroke In Young And Elderly Population.
Authors: Dr.Sharadha Srikanth  , B.Nadia Shulamite  , C. Vamsi Mohan  , K.Sandeep Reddy  , S. Kaveri  
Published: October 2020

Cerebral ischemic stroke is caused by a blockage in a artery that supplies blood to the brain. The blockage reduces the blood flow and oxygen to the brain leading to the damage or death of brain cells. Aim of our study is to identify and analyze the risk factors of cerebral ischemic stroke in young and elderly patients. The known Non modifiable risk factors are Age, Gender, Race,, Family history of stroke, Low birth weight. Modifiable and well documented risk facrors are Hypertension, Sickle cell disease, Atrial fibrillation symptomatic carotid stenosis, Diabetes, Post menopausal hormone therapy, Dyslipidemia. Life style factors-associated with stroke risk Cigarette smoking, Obesity, Over Alcohol consumption, Physical inactivity. Potentially modifiable but less documented risk factors are usage of Oral contraceptives, Migraine,, Drug and alcohol abuse,, Homocysteine condition, Sleep disordered breathing. A Prospective observational study on risk factors of cerebral ischemic stroke in young and elderly patients was performed from September 2018-February 2019 i.e for 6 months duration in In-patient department of General Medicine in Gandhi Hospital.140 CVA cases were collected, documented, analyzed and results are obtained as follows. Young subjects HTN (60.9%), Alcohol consumption (78%), Smoking (48%), History of stroke (36%), Diabetes mellitus (24%), Obesity (14.6%), Cardio-Vascular diseases (4.8%). Elderly subjects HTN (82.8%), Smoking (79%), Alcohol consumption (72.7), History of stroke (33.3%), Diabetes mellitus (27.2), Obesity (8.8%), Cardio-Vascular diseases (8%). Reporting of Stroke cases in young adults in India was uncommon in few years ago. But our studies now indicate that the incidence of young stroke is on the rise. It has been observed that for the past 4-5 years the occurrence of stroke is seen at age less than 45years.And lifestyle modifications can reduce the rate of risk.
Retinopathy of Prematurity –Recent Screening Status in a Tertiary Care Hospital of Bangladesh
Authors: Dr. Maksudur Rahman  , Dr. Dipak Kumar Nag  , Md. Mahbubul Hoque  , Dr. Liton Chandra Saha  
Published: October 2020

Retinopathy of prematurity (ROP) results in severe visual impairment and blindness in newborns. In the recent days with development of the technology to save preterm infants, it’s incidence is increasing in both developed and developing countries. Only appropriate and timely screening program can prevent ROP and reduce the functional impairment of eyes. The aim of this study was to see the recent screening status of the hospital so that future plan of ROP treatment and prevention can be taken more appropriately. This prospective study was conducted from January 2018 to December 2018 in neonatology department of Dhaka Shishu (Children) Hospital. Neonates with gestational age < 34wks or birth weight, <1800gms were screened for ROP. First screening was done at 4 wks chronological age or 32 wks postmenstrual age of neonate which comes later. Then subsequent screening was done according to the findings upto 45 wks of postmenstrual age. The findings regarding incidence of ROP, types of ROP and treatment modalities of ROP along with other variables were recorded. Data were analyzed with SPSS version 17. Total 116 cases were screened for ROP. Mean gestational age was 30.7±2.4 wks and mean weight was 1420.9±313.8 gms. According to gestational age, 14 (12%) neonates with gestational age < 28 wks had ROP. Nine (7.8%) cases had ROP in both gestational age groups of 29-30wks and 31-32wks. Only 5(4.3%) cases with gestational age
33-34wks had ROP. According to birth weight, neonates with birth weight <1000 gms had ROP in 1(0.9%). Twenty four (20.7%) and 12(10.3%) cases had ROP in weight groups of 1000-1499gms and 1500-1800 gms consequently. Thirty one (26.8%) cases were found ROP in their first visit. In 6(5.1%) cases ROP were found in 2nd and subsequent visits. Among the neonates, A-P ROP was present in 15(12.9%) cases, type -1 in 9 (7.7%), type- 2 in 11 (9.6%) and RD in 2(1.7%) cases. Three (2.6%) cases of type 2 ROP turned into type- 1 ROP in subsequent visits. Among the ROP cases, total 29(78%) needed treatment. Laser therapy was given in 7(24%) cases, both laser and intravitreal bivacizumab in 17 (59%) cases, only intravitreal bivacizumab in 2(7%) cases and surgery along with medical treatment was advised for 3(10%) cases. Thirty four (92%) cases had good outcome and 3 (8%) infant had no vision.The incidence of ROP was 31.9% in this study. Most of cases were A-P ROP then Z2S3 ROP. Laser plus intravitreal bivacizumab were given in most of the cases with ROP. The more number of advanced stages of ROP and a large number of babies required treatment indicates that these babies came to us in advanced stages due to irregularity and missing of follow-up.
A Review on Recent Rational Approaches to Drug Design, Development and Its Discovery
Authors: Dheeraj Bisht  , Rajeshwar Kamal Kant Arya  , Govind Raj Pal  , Ravindra Pratap Singh  
Published: October 2020

The steps involved in drug design, drug development and drug discovery are highly expensive, extremely challenging and time consuming. Although the drug designing, process has been hastened with the development of newer emerging techniques, and the fabrication of novel computational tool. Researchers are working on structure guided drug designing using a 3-D structure of target, the drug molecule identified by the use of target-based drug design shows great potential in preventing various diseases but also possess many side effects. In the rational drug design, structure-based designing, combinatorial drug designing and computer aided drug design techniques are employed. When gene expression and bioinformatics are incorporated with the combinatorial drug designing, that make the rational drug designing, a more powerful tool for drug discovery. The rational drug designing associated with gene expression and bioinformatical estimation is moderately emerging and expeditiously revamping the drug development with less time consuming, economic, effectiveness and cater novel combinatory therapy in addition to minimization of toxicity. This review discusses in detail about the fabrication of a successful drug candidate using multidisciplinary perspective of combinatorial chemistry with gene expression analysis, structure based and artificial intelligence- based drug designing. In future, more sophisticated computer-based methodologies would be required for developing new drug candidate.
Induction and Mentoring of Newly Qualified Teachers in Kindergartens and Schools in Norway
Authors: Bjerkholt Eva M. , Olsen Knut-Rune 
Published: October 2020

This article presents the main features of, and analyzes the work on, facilitating induction and mentoring for newly qualified teachers (NQTs) in Norway. The methodological approach is a review of a variety of sources of political, scientific and professional nature.
The article addresses the following research questions: What characterizes the different milestones in the history of induction and mentoring in Norway? Which stakeholders have been active partners in the policymaking, and how has this contributed to changing and developing the national program for induction and mentoring for NQTs in Norway?
The narrative on induction and mentoring in Norway can be divided into four periods, or as we have chosen to call them, milestones. Although each milestone has distinct developmental traits and challenges, our analysis shows some pervasive features that have characterized the work throughout the whole history of induction and mentoring for NQTs in Norway. First, state authorities, represented by the Ministry of Education and Research and the Directorate of Education and Training, have played a key role in leading and facilitating cooperation between the stakeholders. Furthermore, there has been a clear distribution of roles and responsibilities between employee organizations, regional authorities and teacher education institutions.
The history of induction and mentoring in Norway is one of many examples where education, research and politics are intertwined. In 2021, the results of a comprehensive national survey will be published and discussed between the stakeholders before further policy decisions are made.
STRATEGI PENCEGAHAN PENULARAN VIRUS COVID-19 PADA SEKOLAH DASAR DI KECAMATAN PANTE BIDARI ACEH TIMUR
Authors: Yakob Muhammad , Hidayat Muhammad Taufik , Suciani Ayu , Nucifera Prima 
Published: October 2020

Strategi pencegahan penyebaran covid-19 di tingkat satuan pendidikan wajib ditingkatkan. Hal ini untuk mengedukasi siswa menerapkan perilaku hidup bersih dan sehat karena anak-anak yang merupakan golongan rentan terpapar dan tertular Covid-19. Banyak lembaga pendidikan kewalahan dalam membuat pengawasan terhadap anak-anak untuk pencegahan penularan covid-19. Pengabdian masyarakat ini bertujuan memberikan strategi pencegahan virus covid-19 pada Sekolah Dasar di Kec. Pante Bidari, Aceh Timur. Kegiatan PKM ini dilakukan dengan memberikan teori dan strategi pencegahan virus covid-19 pada 4 (empat) Sekolah Dasar yaitu SDN Pante Panah, SDN Paya Demam Dua, SDN Lhoknibong, dan SDN Bandar Baru Kabupaten Aceh Timur. Metode yang digunakan dalam pengabdian ini adalah pendekatan kualitatif dengan jenis penelitian deskriptif. Subjek dalam pengabdian ini adalah guru kelas dan siswa di wilayah kabupaten Aceh Timur. Tahap pelaksanaan dilakukan dengan tiga tahapan, yaitu survei, koordinasi, dan monitoring dan evaluasi. Tahap pertama merupakan tahap persiapan. Pada tahap ini kelompok pengabdi melakukan survey pendahuluan untuk melihat kondisi di lapangan mengenai strategi pencegahan virus covid-19 pada sekolah dasar di Kec. Pante Bidari, Aceh Timur dihasilkan oleh masyarakat. Tahapan kedua strategi yang kreatif dan inovatif sebagai upaya pencegahan Covid-19. Tahap yang terakhir adalah tahap monitoring dan evaluasi. Pada tahap ini dilakukan evaluasi atas hasil yang telah dicapai oleh masyarakat. Berdasarkan hasil pengabdian, disosialisasikan sepuluh strategi pencegahan covid- 19, yaitu rajin mencuci tangan dengan benar, menggunakan hand sanitizer jika tidak ada air dan sabun, menggunakan masker secara benar, menggunakan face shield, penyemprotan disinfektan, memberi vitamin sebagai imun booster, menggunakan tisu saat bersin dan batuk, menghindari bepergian selama pandemi, dan menghindari kontak langsung dengan orang lain.
"Weekend tourism" - a tourism product aimed at customers living and working in big cities in Vietnam (Case study of Binh Duong Province)
Authors: Phan Xuan Thi Hong 
Published: October 2020

To implement this article, we have chosen the research area of ​​Binh Duong (bordering Ho Chi Minh City, with a history of over 300 years of development, with 11 years of operating the type of weekend tourism from 2008 to present); have used some research methods in social sciences, particularly ethnographic fieldwork such as strategic interview, comparing and analyzing data gathered from multiple sources. The article consists of 3 parts:
(1) The concept of "Weekend tourism" and specific products
(2) Identify key factors affecting the exploitation of the "weekend tourism" type in Binh Duong
(3) A number of measures to contribute to the development of "weekend tourism" in the context of international integration.
La radio universitaria y los aprendizajes estudiantiles
Authors: Martínez Ibarra Jorge Arturo , Arellano Montoya Rosa Elena 
Published: October 2020

En este trabajo se presentan los aprendizajes y las experiencias obtenidas por estudiantes de diversas áreas disciplinares del Centro Universitario del Sur de la Universidad de Guadalajara (México) que participaron de «En el camino andamos», un programa radiofónico producido por Radio Universidad de Guadalajara-Ciudad Guzmán. El proceso metodológico incluyó entrevistas en profundidad con los/as estudiantes y con los/as productores, la observación participante para identificar las relaciones de los/as colaboradores durante el proceso de producción, y la definición de categorías de análisis para la sistematización y la interpretación de la información recabada.
STUDI LITERATUR: PEMBERIAN POSISI SEMI FOWLER PADA PASIEN TB PARU DENGAN MASALAH KEPERAWATAN KETIDAKEFEKTIFAN POLA NAFAS
Authors: Santoso Krisnadina Bunaina , Andarmoyo Sulistyo , Sari Rika Maya 
Published: October 2020

TB paru merupakan penyakit paru yang disebabkan bakteri Mycobacterium tuberculosis yang mengakibatkan gangguan sistem pernafasan. Salah satu gejalanya adalah sesak nafas, nyeri dada, dan peningkatan respiration rate, sehingga muncul gangguan ketidakefektifan pola nafas. Tindakan sederhana untuk mengatasi masalah ini dengan memberikan posisi semi fowler, tujuannya untuk membantu memaksimalkan ekspansi paru sehingga terjadi perubahan respiration rate dan pola nafas menjadi efektif. Metode penulisan ini dengan mencari beberapa jurnal di Google Scholar, didapatkan hasil penelusuran dari 3 jurnal menurut Suhadridjat dan Isnayati (2020), dan Aneci Boki Majampoh dkk (2013) bahwa pemberian posisi semi fowler kemiringan 30-45° membantu pengembangan paru dan mengurangi tekanan dari abdomen pada diafragma. Sedangkan menurut Roihatul Zahroh dan Rivai Sigit Susanto (2017), posisi orthopnea lebih efektif daripada semi fowler karena posisi duduk dengan badan dicondongkan ke depan dianjurkan sebagai terapi intervensi untuk meringankan sesak nafas dan meningkatkan fungsi paru, dengan hasil rata-rata penurunan sesak nafas 5 dibandingkan posisi semi fowler dengan rata-rata penurunan sesak nafas 4. Dapat disimpulkan bahwa pemberian posisi semi fowler dan posisi orthopnea dapat membantu menurunkan sesak nafas pada pasien TB paru namun posisi orthopnea lebih dianjurkan untuk penurunan sesak nafas pada pasien TB paru.
LITERATURE REVIEW : HUBUNGAN MOTIVASI KERJA PERAWAT DENGAN KINERJA PERAWAT DALAM PENGISIAN DOKUMENTASI ASUHAN KEPERAWATAN
Authors: Wigatama Adelia Septi , Munawaroh Siti , Dwirahayu Yayuk 
Published: October 2020

Pengukuran kinerja merupakan serangkaian kegiatan perawat yang memiliki kompetensi pengetahuan, keterampilan, dan pengambilan keputusan klinis. Kualitas dokumentasi asuhan keperawatan dipengaruhi oleh tingkat pengetahuan perawat dalam melakukan pendokumentasian dengan tata bahasa yang baik. Pentingnya motivasi dan komitmen perawat terhadap tujuan dan kebijakan organisasi adalah sebagai daya dorong dalam meningkatkan kinerja perawat. Pencarian jurnal atau artikel ini menggunakan sumber data yang sekunder yang didapat berupa jurnal yang relevan dengan topic dilakukan menggunakan database melalui Willey Library, Google Scholar, dan DOAJ. Hasil dari 1 artikel yang membahas mengenai motivasi kerja perawat didapatkan satu artikel dengan presentase tertinggi yaitu (69,0%) dengan tingkat motivasi kerja yang baik, dan hasil dari 6 artikel yang membahas mengenai kinerja perawat dalam pengisian dokumentasi asuhan keperawatan didapatkan satu artikel dengan presentase tertinggi yaitu (69,8%) yang memiliki kinerja yang baik dalam pengisian dokumentasi asuhan keperawatan. Berdasarkan hasil literature review pada 7 artikel terkait “Hubungan Motivasi Kerja Perawat Dengan Kinerja Perawat Dalam Pengisian Dokumentasi Asuhan Keperawatan” dapat ditarik kesimpulan ada 6 jurnal penelitian yang mengatakan terdapat hubungan yang signifikan antara motivasi kerja dengan kinerja perawat.