bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genome-wide analysis of fatty acid desaturase genes in rice (Oryza sativa L.)
Authors: E Zhiguo , Chen Chen , Yang Jinyu , Tong Hanhua , Li Tingting , Wang Lei , Chen Hongqi 
Published: December 2019

AbstractFatty acid desaturases can catalyze saturated or unsaturated fatty acids to form a double bond at various locations in the hydrocarbon chain. In the present study, a total of 20 full-length desaturase genes were identified from rice genome. An exhaustive analysis was performed to describe their chromosomal locations, gene structures, phylogeny, cis-regulatory elements, sub-cellular localizations and expression patterns. The rice desaturase genes were distributed on ten of 12 chromosomes and phylogenetically classified into six subfamilies with the Arabidopsis counterparts, FAB2, FAD2, FAD3/7/8, FAD6, DES1 and SLD1. Among of them, 9 members were expanded via chromosomal tandem or segmental duplications. The gene structures and motif constituents were evolutionarily conserved in the same subfamilies. The majority of desaturase genes showed tissue-specific expression patterns and response to abiotic stresses and hormones based on microarray data and qRT-PCR analyses. This study will provide useful clues for functional validation of desaturase genes and contribute to produce nutritionally important fatty acids by genetic modification in rice.
Fabrication of functionalized electrospun carbon nanofibers for enhancing lead-ion adsorption from aqueous solutions
Authors: Thamer Badr M. , Aldalbahi Ali , Moydeen A Meera , Al-Enizi Abdullah M. , El-Hamshary Hany , El-Newehy Mohamed H. 
Published: December 2019

AbstractElectrospinning technique is a simple and cheap method for fabrication of electrospun nanofibers (ENFs), which in turn can converted into electrospun carbon nanofibers (ECNFs) by carbonization process. The controlling of the ECNFs properties (e.g. surface area, porosity, diameters) during fabrication, make it superior over the other carbon nanomaterials. The aim of our study is to modify the surface of ECNFs to increase its hydrophilicity and in turn its efficiency in removing lead ions (Pb2+) from aqueous systems. The surface modification was carried out in two steps starting from oxidation of pristine ECNFs to produce oxidized ECNFs (o-ECNFs), followed by covalently bonded of melamine, and poly(m-phenylene diamine) for forming melamine-functionalized ECNFs (melam-ECNFs) and poly(m-phenylene diamine)-functionalized ECNFs (PmPDA-ECNFs), respectively. The as-prepared materials were characterized in routine way. The ability of the as-prepared materials towards adsorption of Pb2+ ions as heavy metal was investigated with the study of some factors such as pH solution, contact time, initial concentration and temperature. The adsorption process was analyzed isothermally, and kinetically. According to the values of the thermodynamic parameters, the adsorption of Pb2+ ions onto the functionalized ECNFs was endothermic and spontaneous, except with melam-ECNFs was exothermic.
Fine-scale invasion genetics of the quarantine pest, Anoplophora glabripennis, reconstructed in single outbreaks
Authors: Tsykun Tetyana , Javal Marion , Hölling Doris , Roux Géraldine , Prospero Simone 
Published: December 2019

AbstractThe xylophagous cerambycid Anoplophora glabripennis, the Asian long-horned beetle (ALB), is highly polyphagous and can colonize a wide range of broadleaved host trees causing significant economic damage. For this reason, it is considered a quarantine pest in Europe and North America. Although the global spread of ALB has been depicted recently, no comprehensive studies exist on the genetic pattern of populations’ establishment and dynamics at fine-scale (i.e. within invasive outbreaks), before eradication measures are applied. This information may, however, be particularly important for an efficient management and control of invasive pests. Here, we characterized population genetic diversity and patterns of spread of ALB within and among the four outbreaks detected in Switzerland between 2011 and 2015. For this, we genotyped 223 specimens at 15 nuclear microsatellite loci and conducted specific population-based analyses. Our study shows: (1) At least three independent introductions and a, human-mediated, secondary dispersal event leading to the four outbreaks in the country; (2) An overall low intra-population genetic diversity in the viable and several years active invasive populations; (3) A colonization of single trees by homogeneous ALB genotypes; And (4) an establishment of populations several generations prior to its official discovery.
Synthesis of WS1.76Te0.24 alloy through chemical vapor transport and its high-performance saturable absorption
Authors: Du Zhengting , Zhang Chi , Wang Mudong , Zhang Xuejin , Ning Jian , Lv Xinjie , Zhao Gang , Xie Zhenda , Xu Jinlong , Zhu Shining 
Published: December 2019

AbstractLayered transitional metal dichalcogenides (TMDs) are drawing significant attentions for the applications of optics and optoelectronics. To achieve optimal performances of functional devices, precisely controlled doping engineering of 2D TMDs alloys has provided a reasonable approach to tailor their physical and chemical properties. By the chemical vapor transport (CVT) method and liquid phase exfoliation technique, in this work, we synthesized WS1.76Te0.24saturable absorber (SA) which exhibited high-performance of nonlinear optics. The nonlinear saturable absorption of the WS1.76Te0.24SA was also measured by the open aperture Z-scan technique. Compared to that of the binary component WS2and WTe2, WS1.76Te0.24SA has shown 4 times deeper modulation depth, 28% lower saturable intensity and a much faster recovery time of 3.8 ps. The passively Q-switched laser based on WS1.76Te0.24was more efficient, with pulse duration narrowed to 18%, threshold decreased to 28% and output power enlarged by 200%. The promising findings can provide a method to optimize performances of functional devices by doping engineering.
Pre-disaster social support is protective for onset of post-disaster depression: Prospective study from the Great East Japan Earthquake & Tsunami
Authors: Sasaki Yuri , Aida Jun , Tsuji Taishi , Koyama Shihoko , Tsuboya Toru , Saito Tami , Kondo Katsunori , Kawachi Ichiro 
Published: December 2019

AbstractWe examined whether pre-disaster social support functions as a disaster preparedness resource to mitigate post-disaster depressive symptoms among older survivors of the 2011 Great East Japan earthquake and tsunami. The participants were 3,567 individuals aged ≥65 years living in Iwanuma city who completed a baseline survey as part of the nationwide Japan Gerontological Evaluation Study seven months before the disaster. A follow-up survey was administered approximately 2.5 years after the disaster. The analysis included a total of 2,293 participants, and social support (giving and receiving emotional & instrumental help) before the disaster was measured using four items. Depressive symptoms were assessed using the GDS with a cut-off score of 4/5 (not depressed/depressed). We discovered that participants who gave and received emotional and instrumental support before the disaster were significantly less likely to develop depressive symptoms after the disaster compared to those without support (ARR = 0.70; 95% CI: 0.56–0.88). The risk of the onset of depressive symptoms was 1.34 (95% CI: 1.03–1.74) among those who experienced disaster damages but had also given and received social support, and 1.70 (95% CI: 1.03–2.76) among those who experienced damages but lacked support. Strengthening social aid may help cultivate psychological resilience to disasters.
Electromagnetic Burst Generation during Annihilation of Magnetic Field in Relativistic Laser-Plasma Interaction
Authors: Gu Y. J. , Pegoraro F. , Sasorov P. V. , Golovin D. , Yogo A. , Korn G. , Bulanov S. V. 
Published: December 2019

AbstractWe present the results of theoretical studies of formation and evolution of the current sheet in a colliosionless plasma during magnetic reconnection in relativistic limit. Relativistic magnetic reconnection is driven by parallel laser pulses interacting with underdense plasma target. Annihilation of laser created magnetic field of opposite polarity generates strong non-stationary electric field formed in between the region with opposite polarity magnetic field accelerating charged particles within the current sheet. This laser-plasma target configuration is discussed in regard with the laboratory modeling of charged particle acceleration and gamma flash generation in astrophysics. We present the results of 3-dimensional kinetic simulations and theoretical studies on the formation and evolution of the current sheet in a collisionless plasma during magnetic field annihilation in the ultra-relativistic limit. Annihilation of oppositively directed magnetic fields driven by two laser pulses interacting with underdense plasma target is accompanied by an electromagnetic burst generation. The induced strong non-stationary longitudinal electric field accelerates charged particles within the current sheet. Properties of the laser-plasma target configuration are discussed in the context of the laboratory modeling for charged particle acceleration and gamma flash generation in astrophysics.
The Imaging Resolution and Knudsen Effect on the Mass Transport of Shale Gas Assisted by Multi-length Scale X-Ray Computed Tomography
Authors: Iacoviello Francesco , Lu Xuekun , Mitchell Thomas M. , Brett Daniel J. L. , Shearing Paul R. 
Published: December 2019

AbstractThe spatial resolution of 3D imaging techniques is often balanced by the achievable field of view. Since pore size in shales spans more than two orders of magnitude, a compromise between representativeness and accuracy of the 3D reconstructed shale microstructure is needed. In this study, we characterise the effect of imaging resolution on the microstructural and mass transport characteristics of shales using micro and nano-computed tomography. 3D mass transport simulation using continuum and numerical physics respectively is also compared to highlight the significance of the Knudsen effect on the reconstructed solid surface. The result shows that porosity measured by micro-CT is 25% lower than nano-CT, resulting in an overestimated pore size distribution and underestimated pore connectivity. This leads to a higher simulated intrinsic permeability. An overestimated diffusive flux and underestimated permeability are obtained from the continuum mass transport simulation compared to the numerical ones when the molecular-wall collision is accounted, evidenced by the large deviation of the measured Knudsen tortuosity factor and permeability correction factor. This study is believed to provide new knowledge in understanding the importance of imaging resolution and gas flow physics on mass transport in porous media.
Long-term outcomes of HBsAg/anti-HBs double-positive versus HBsAg single-positive patients with chronic hepatitis B
Authors: Kwak Min-Sun , Chung Goh-Eun , Yang Jong In , Yim Jeong Yoon 
Published: December 2019

AbstractThe coexistence of HBsAg and anti-HBs has been reported in some chronic hepatitis B patients; however, the long-term outcomes of this serological profile have not been elucidated. We aimed to evaluate the long-term outcomes of HBsAg/anti-HBs double-positive chronic hepatitis B patients. Chronic hepatitis B patients who underwent baseline abdominal ultrasonography and follow-up (HBsAg/anti-HBs assessment and abdominal ultrasonography) at our healthcare center were included. The “coexistence group” included patients positive for both HBsAg and anti-HBs and the “control group” included patients positive for only HBsAg during follow-up. The outcomes were hepatocellular carcinoma (HCC) incidence, HBsAg seroclearance and overall mortality. Kaplan-Meier and Cox proportional hazard regression analyses were performed. Of the 2,341 eligible patients, 166 (7.1%) were in the coexistence group. The total follow-up duration was 5.4 years. The coexistence group had a 3.08-fold higher risk of HCC than the control group [hazard ratio (HR) 3.08, 95% confidence interval(CI) 1.26–7.55, P = 0.014] in multivariate analysis. The coexistence group had more HBsAg seroclearance than the control group (HR 1.43, 95% CI 1.01–2.03, P = 0.046). However, overall mortality did not significantly differ between the 2 groups. The coexistence group is heterogeneous and includes subjects with unfavorable outcomes (incidence of HCC) and favorable outcomes (more HBsAg seroclearance).
Linking flow-stream variability to grain size distribution of suspended sediment from a satellite-based analysis of the Tiber River plume (Tyrrhenian Sea)
Authors: Pitarch J. , Falcini F. , Nardin W. , Brando V. E. , Di Cicco A. , Marullo S. 
Published: December 2019

AbstractSeveral coastal regions on Earth have been increasingly affected by intense, often catastrophic, flash floods that deliver significant amounts of sediment along shorelines. One of the critical questions related to the impact of these impulsive runoffs is “are flash floods more efficient in delivering non-cohesive sandy sediment along the coasts?” Here we relate flow stages (i.e., from erratic to persistent) to the grain size distribution of the suspended load, by performing a synergic analysis of in-situ river discharge and satellite-retrieved grain size distribution, from 2002 to 2014, covering the 2012 Tiber River (Italy) exceptional flood event. Our analysis shows novel and promising results regarding the capability of remote sensing in characterizing suspended sediment in terms of grain size distribution and reveals that erratic stages favour delivering of non-cohesive sandy sediment more than the persistent stages. This conclusion is supported by numerical simulations and is consistent with previous studies on suspended sediment rating curves.
FOXM1/LINC00152 feedback loop regulates proliferation and apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via Wnt/β-catenin signaling pathway
Authors: Wang Wenlong , Guo Piaopiao , Chen Mengjie , Chen Die , Cheng Yongjun , He Long 
Published: December 2019

Abstract
Rheumatoid arthritis (RA), a chronic systemic disease, is featured with inflammatory synovitis, which can lead to destruction on bone and cartilage and even cause disability. Emerging studies demonstrated that Fibroblast-like synoviocytes (FLS) is a vital cellular participant in RA progression. Long non-coding RNAs (lncRNAs) are also reported to participate in the pathogenesis of RA. In our present study, lncRNA microarray analysis was applied to screen out lncRNAs differentially expressed in RA FLS. Among which, cytoskeleton regulator RNA (LINC00152) presented biggest fold change. Gain- or loss-of function assays were further carried out in RA FLS, and the results revealed that LINC00152 promoted proliferation but induced apoptosis in RA FLS. Furthermore, up-regulation of LINC00152 may induce promotion of Wnt/β-catenin signaling pathway in RA FLS. Mechanistically, we found that forkhead box M1 (FOXM1) transcriptionally activated LINC00152 in RA FLS. Additionally, LINC00152 positively regulated FOXM1 via sponging miR-1270. In conclusion, the present study focused on elucidating the function of FOXM1/LINC00152 positive feedback loop in RA FLS and its association with Wnt/β-catenin signaling.
Circulating endocan and preeclampsia: a meta-analysis
Authors: Lan Xia , Liu Zhaoming 
Published: December 2019

AbstractBackground: Endocan, a novel protein involved in inflammation and endothelial dysfunction, has been suggested to be related to preeclampsia, although the results of previous studies were not consistent. The aim of the study was to evaluate the potential difference of circulating endocan in women with preeclampsia and those with normal pregnancy.Methods: Matched case–control studies evaluating the difference of circulating endocan between women with preeclampsia and those with normal pregnancy were identified via systematic search of PubMed and Embase databases. A random-effect model or a fixed-effect model was used to pool the results according to the heterogeneity. Subgroup analysis was performed to evaluate whether the timing of preeclampsia onset affected the outcome.Results: Overall, eight matched case–control studies, including 451 women with preeclampsia and 442 women with normal pregnancy were included. Significant heterogeneity was detected among the included studies (P for Cochrane’s Q test = 0.006, I2 = 65%). Meta-analysis with a random-effect model showed that women with preeclampsia had significantly higher circulating level of endocan compared with women with normal pregnancy (standardized mean difference = 0.37, 95% confidence interval: 0.13–0.62, P = 0.003). Subsequent subgroup analyses showed that the difference of circulating endocan between women with early onset preeclampsia and those with normal pregnancy was not statistically different from that between women with late-onset preeclampsia and those with normal pregnancy (P for subgroup difference = 0.81).Conclusions: Women with preeclampsia have higher circulating endocan than those with normal pregnancy.
Individual Differences in Lexical Access Among Cochlear Implant Users
Authors: Nagels Leanne , Bastiaanse Roelien , Başkent Deniz , Wagner Anita 
Published: December 2019

Purpose
The current study investigates how individual differences in cochlear implant (CI) users' sensitivity to word–nonword differences, reflecting lexical uncertainty, relate to their reliance on sentential context for lexical access in processing continuous speech.

Method
Fifteen CI users and 14 normal-hearing (NH) controls participated in an auditory lexical decision task (Experiment 1) and a visual-world paradigm task (Experiment 2). Experiment 1 tested participants' reliance on lexical statistics, and Experiment 2 studied how sentential context affects the time course and patterns of lexical competition leading to lexical access.

Results
In Experiment 1, CI users had lower accuracy scores and longer reaction times than NH listeners, particularly for nonwords. In Experiment 2, CI users' lexical competition patterns were, on average, similar to those of NH listeners, but the patterns of individual CI users varied greatly. Individual CI users' word–nonword sensitivity (Experiment 1) explained differences in the reliance on sentential context to resolve lexical competition, whereas clinical speech perception scores explained competition with phonologically related words.

Conclusions
The general analysis of CI users' lexical competition patterns showed merely quantitative differences with NH listeners in the time course of lexical competition, but our additional analysis revealed more qualitative differences in CI users' strategies to process speech. Individuals' word–nonword sensitivity explained different parts of individual variability than clinical speech perception scores. These results stress, particularly for heterogeneous clinical populations such as CI users, the importance of investigating individual differences in addition to group averages, as they can be informative for clinical rehabilitation.

Supplemental Material

https://doi.org/10.23641/asha.11368106
Sync Pending: Characterizing Conversational Entrainment in Dysarthria Using a Multidimensional, Clinically Informed Approach
Authors: Borrie Stephanie A. , Barrett Tyson S. , Liss Julie M. , Berisha Visar 
Published: December 2019

PurposeDespite the import of conversational entrainment to successful spoken dialogue, the systematic characterization of this behavioral syncing phenomenon represents a critical gap in the field of speech pathology. The goal of this study was to acoustically characterize conversational entrainment in the context of dysarthria using a multidimensional approach previously validated in healthy populations (healthy conversations;Borrie, Barrett, Willi, & Berisha, 2019).MethodA large corpus of goal-oriented conversations between participants with dysarthria and healthy participants (disordered conversations) was elicited using a “spot the difference” task. Expert clinical assessment of entrainment and a measure of conversational success (communicative efficiency) was obtained for each of the audio-recorded conversations. Conversational entrainment of acoustic features representing rhythmic, articulatory, and phonatory dimensions of speech was identified using cross-recurrence quantification analysis with clinically informed model parameters and validated with a sham condition involving conversational participants who did not converse with one another. The relationship between conversational entrainment and communicative efficiency was examined.ResultsAcoustic evidence of entrainment was observed in phonatory, but not rhythmic and articulatory, behavior, a finding that differs from healthy conversations in which entrainment was observed in all speech signal dimensions. This result, that disordered conversations showed less acoustic entrainment than healthy conversations, is corroborated by clinical assessment of entrainment in which the disordered conversations were rated, overall, as being less in sync than healthy conversations. Furthermore, acoustic entrainment was predictive of communicative efficiency, corroborated by a relationship between clinical assessment and the same outcome measure.ConclusionsThe findings confirm our hypothesis that the pathological speech production parameters of dysarthria disrupt the seemingly ubiquitous phenomenon of conversational entrainment, thus advancing entrainment deficits as an important variable in dysarthria, one that may have causative effects on the success of everyday communication. Results further reveal that while this approach provides a broad overview, methodologies for characterizing conversational entrainment in dysarthria must continue to be developed and refined, with a focus on clinical utility.Supplemental Materialhttps://osf.io/ktg5q
Tongue Part Movement Trajectories for /r/ Using Ultrasound
Authors: Dugan Sarah , Li Sarah R. , Masterson Jack , Woeste Hannah , Mahalingam Neeraja , Spencer Caroline , Mast T. Douglas , Riley Michael A. , Boyce Suzanne E. 
Published: December 2019

Purpose
Because it shows the movement of different parts of the tongue in real time, ultrasound biofeedback therapy is a promising technology for speech research and remediation. One limitation is the difficulty of interpreting real-time ultrasound images of tongue motion. Our image processing system, TonguePART, tracks the tongue surface and allows for the acquisition of quantitative tongue part trajectories.

Method
TonguePART automatically identifies the tongue contour based on ultrasound image brightness and tracks motion of the tongue root, dorsum, and blade in real time. We present tongue part trajectory data from 2 children with residual sound errors on /r/ and 2 children with typical speech, focusing on /r/ (International Phonetic Alphabet ɹ) in the phonetic context /ɑr/. We compared the tongue trajectories to magnetic resonance images of sustained vowel /ɑ/ and /r/.

Results
Measured trajectories show larger overall displacement and greater differentiation of tongue part movements for children with typical speech during the production of /ɑr/, compared to children with residual speech sound disorders.

Conclusion
TonguePART is a fast, reliable method of tracking articulatory movement of tongue parts for syllables such as /ɑr/. It is extensible to other sounds and phonetic contexts. By tracking tongue parts, clinical researchers can investigate lingual coordination. TonguePART is suitable for real-time data collection and biofeedback. Ultrasound biofeedback therapy users may make more progress using simplified biofeedback of tongue movement.