bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bedtime Routines Intervention for Children (BRIC) using an automated text messaging system for behaviour change: study protocol for an early phase study
Authors: Kitsaras George , Allan Julia , Pretty Iain A. 
Published: February 2020

Abstract
Background
This work concerns the activities in the last hour before bed for young children born to first-time parents, so called bedtime routines (BTR). These activities include amongst others tooth brushing, reading a book, having a bath and avoiding food and drinks before bed. Having a set bedtime at a suitable hour is also very important. Establishing good bedtime routines has been shown to be really important for a number of health, wellbeing, development and social outcomes. Currently, there is no evidence-based bedtime routine intervention for first-time parents using a novel design (i.e. text messages). Existing research has highlighted the importance of bedtime routines and the lack of appropriate mechanisms in place for parents who sought support.

Methods
The proposed study includes 2 work packages. Work package 1 focuses on the development of the intervention through a combination of qualitative work (1:1 interviews with parents on barriers and facilitators on bedtime routines using the Theoretical Domains Framework) and an expert group of key stakeholders. Work package 2 involves a small-scale (n = 50) feasibility and effectiveness study to examine proof of concept with first-time parents using text messages to communicate the intervention. Quantitative information relating to uptake, engagement, retention and effectiveness of the intervention as well as qualitative information (focus groups with parents who took part in the study) will be collected. Overall, the effectiveness of the intervention will be assessed through the APEASE criteria (acceptability, practicability, effectiveness, affordability, safety, equity).

Discussion
This study can provide initial yet important support for further exploration in the field of bedtime routines in more complicated family structures (parents with more than 1 child, separated families etc.). Also, the implementation of a novel study design (i.e. text messages) could lead to considerable cost savings while maintaining high retention, uptake and engagement from the participants. Should the intervention meet the APEASE criteria, a more comprehensive intervention on bedtime routines for first-time parents will be explored in a more robust (RCT and longitudinal) approach.

Trials registration
Due to the nature of the study, no trial registration is currently in place.
Nexus between foreign direct investment and economic growth in Bangladesh: an augmented autoregressive distributed lag bounds testing approach
Authors: Sarker Bibhuti , Khan Farid 
Published: February 2020

AbstractThe relationship between foreign direct investment (FDI) inflows and economic growth in host countries is a heavily debated issue. Although some studies have found evidence of the positive impact of FDI on economic growth, others have revealed the opposite result. Studies that examined the causality between FDI and gross domestic product (GDP) also have found evidence of unidirectional causality and, in some cases, a bidirectional causality. This study investigated the causal nexus between FDI and GDP in Bangladesh by employing standard time-series econometric tools, namely, augmented Dickey-Fuller, augmented Dickey-Fuller generalized least square, Kwiatkowski-Phillips-Schmidt-Shin, and Lee-Strazicich unit root tests to check stationarity, augmented autoregressive distributed lag (augmented ARDL) bounds testing approach to check cointegration, and Granger causality to explore the direction of causality. The augmented ARDL model found a long-run relationship between FDI and GDP. In addition, the error correction model and Granger causality results indicated the presence of a unidirectional causality running from GDP to FDI.
Distributed ledger technology for securities clearing and settlement: benefits, risks, and regulatory implications
Authors: Priem Randy 
Published: February 2020

AbstractThis article outlines the benefits and risks of the distributed ledger technology (DLT) for the clearing and settlement of exchange-traded and OTC securities, followed by a description of the technology’s potential role for central counterparties and central securities depositories. Although the industry and scholars are attempting to solve the technological and operational issues that DLT systems still face, outstanding legal risks are such that the financial industry is asking for more regulatory guidance and intervention. This article wants to contribute to the public policy debate by presenting potential regulatory barriers that may have to be removed for DLT to be fully adopted. In addition, it identifies areas requiring an update of the legal framework in order to address certain prudential and conduct risks that this technology could introduce.
Abnormal behaviors during sleep from the viewpoint of sleep epileptology: current and future perspectives on diagnosis
Authors: Chiba Shigeru 
Published: February 2020

AbstractAbnormal behaviors during sleep (ABDS) exhibit a myriad of symptoms. Their underlying diseases are also diverse, which include NREM/REM-related parasomnias, epilepsy and mental disorders. Since ABDS may severely affect a patient’s quality of life, giving an early and accurate diagnosis of the underlying disease (by analyzing video-polysomnographic data during the manifestation of ABDS) is of great importance. However, accurate diagnosis of ABDS is rather difficult. Recently it has been suggested that the pathology of (NREM/REM-related) parasomnias and epilepsy are closely related. In order to unravel the pathophysiological substrate of ABDS, it is essential to develop a novel approach based on sleep epileptology, a field which targets the interface between sleep medicine and epileptology.
Determining the effective number and surfaces of teeth for forensic dental identification through the 3D point cloud data analysis
Authors: Kurniawan Arofi , Yodokawa Kouya , Kosaka Moe , Ito Koichi , Sasaki Keiichi , Aoki Takafumi , Suzuki Toshihiko 
Published: February 2020

Abstract
Background
The assimilation between three-dimensional (3D) imaging techniques and dental forensic science can provide rich and stable information for human identification. This study aimed to determine the effective number and surfaces of teeth for dental identification through the 3D imaging approach.

Material and methods
In the present study, maxillary dental casts were fabricated from subjects who met the inclusion criteria and scanned using a 3D scanner Vivid 910. Rapidform XOS/SCAN software was used to create and trim the 3D point cloud data. Subsequently, two types of 3D surface data of dental casts were registered and the root mean square errors (RMSEs) between subjects were calculated using iterative closest point (ICP) algorithm in MATLAB. Two sets of experiments with 120 combinations of the superimposed 3D dataset were designed, termed as experiments 1 and 2.

Results
In experiment 1, the difference between subjects was clearly distinguished with a minimum of six teeth of the dental arch. The results of experiment 2 suggest that the labial surfaces of the anterior teeth are sufficient to be used for dental identification.

Conclusion
Through these experiments for all possible pairs of subjects, a clear difference was observed in the RMSE between the genuine and imposter pairs. These results indicate the potential of using the 3D imaging technique to achieve highly accurate human identification. It is suggested that a future study with a larger sample number will evaluate the robustness and accuracy of this method.
Imaging of sino-nasal inverted papilloma: How can we emphasize the usefulness of the “striated pattern” sign?
Authors: Eid Mohamed , Eissa Lamya 
Published: February 2020

AbstractBackgroundInverted papilloma (IP) is an uncommon sino-nasal neoplasm with potentially distinctive MRI and CT features. The MR “striated” imaging pattern has been reported as a valuable MR imaging feature of IP. The purpose of this study was to validate the usefulness of this sign using detailed criteria of the sign itself.ResultsAll imaging findings were described for 16 patients in descriptive pattern. The nasal involvement showed highest prevalence followed by the maxillary sinus. The bony changes include remodeling and defects (n= 6), remodeling only (n= 4), and None (n= 6). Changes were severe 1/10, moderate in 3/10, and mild 5/10. Focal hyperostosis was seen in six. A striated pattern was “diffuse” in all 16 (100%) of the IPs; it followed acertain directionin all 16 patients: divergent (n= 6), convoluted (n= 2), and parallel (n= 8). Divergent growth from focal hyperostosis was seen (n= 4). Visibility of the sign was superior in T2 images (n= 11), superior in enhanced images (n= 3), and equal in both (n= 2).ConclusionsThe striated pattern is a reliable MR imaging feature of sino-nasal IPs. Validity and usefulness of this sign can be emphasized by defining parameters of the signs itself including the following: diffusivity, direction of striations and relation to hyperostosis, and comparing visibility in both T2 and GAD-enhanced images, as well as combining this imaging signature with remolding bony changes < 1.5.
Cardiac abnormalities identified with echocardiography in anorexia nervosa: systematic review and meta-analysis
Authors: Smythe Jodie , Colebourn Claire , Prisco Lara , Petrinic Tatjana , Leeson Paul 
Published: February 2020

BackgroundAnorexia nervosa affects most organ systems, with 80% suffering from cardiovascular complications.AimsTo define echocardiographic abnormalities in anorexia nervosa through systematic review and meta-analysis.MethodTwo reviewers independently assessed eligibility of publications from Medline, EMBASE and Cochrane Database of Systematic Reviews registries. Studies were included if anorexia nervosa was the primary eating disorder and the main clinical association in described cardiac abnormalities. Data was extracted in duplicate and quality-assessed with a modified Newcastle–Ottawa scale. For continuous outcomes we calculated mean and standardised mean difference (SMD), and corresponding 95% confidence interval. For dichotomous outcomes we calculated proportion and corresponding 95% confidence interval. For qualitative data we summarised the studies.ResultsWe identified 23 eligible studies totalling 960 patients, with a mean age of 17 years and mean body mass index of 15.2 kg/m2. Fourteen studies (469 participants) reported data suitable for meta-analysis. Cardiac abnormalities seen in anorexia nervosa compared with healthy controls were reduced left ventricular mass (SMD 1.82, 95% CI 1.32–2.31, P < 0.001), reduced cardiac output (SMD 1.92, 95% CI 1.38–2.45, P < 0.001), increased E/A ratio (SMD −1.10, 95% CI −1.67 to −0.54, P < 0.001), and increased incidence of pericardial effusions (25% of patients, P < 0.01, 95% CI 17–34%, I2 = 80%). Trends toward improvement were seen with weight restoration.ConclusionsPatients with anorexia nervosa have structural and functional cardiac changes, identifiable with echocardiography. Further work should determine whether echocardiography can help stratify severity and guide safe patient location, management and effectiveness of nutritional rehabilitation.
Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression
Authors: Paksarian Diana , Trabjerg Betina B. , Merikangas Kathleen R. , Mors Ole , Børglum Anders D. , Hougaard David M. , Nordentoft Merete , Werge Thomas , Pedersen Carsten B. , Mortensen Preben B. , Agerbo Esben , Horsdal Henriette Thisted 
Published: February 2020

BackgroundResidential mobility during upbringing, and especially adolescence, is associated with multiple negative mental health outcomes. However, whether associations are confounded by unmeasured familial factors, including genetic liability, is unclear.AimsWe used a population-based case–cohort study to assess whether polygenic risk scores (PRSs) for schizophrenia, bipolar disorder and major depression were associated with mobility from ages 10–14 years, and whether PRS and parental history of mental disorder together explained associations between mobility and each disorder.MethodInformation on cases (n = 4207 schizophrenia, n = 1402 bipolar disorder, n = 18 215 major depression) and a random population sample (n = 17 582), born 1981–1997, was linked between Danish civil and psychiatric registries. Genome-wide data were obtained from the Danish Neonatal Screening Biobank and PRSs were calculated based on results of separate, large meta-analyses.ResultsPRSs for schizophrenia and major depression were weakly associated with moving once (odds ratio 1.07, 95% CI 1.00–1.16; and odds ratio 1.10, 95% CI 1.04–1.17, respectively), but not twice or three or more times. Mobility was positively associated with each disorder, with more moves associated with greater risk. Adjustment for PRS produced slight reductions in the magnitude of associations. Adjustment for PRS and parental history of mental disorder together reduced estimates by 5–11%. In fully adjusted models mobility was associated with all three disorders; hazard ratios ranged from 1.33 (95% CI 1.08–1.62; one move and bipolar disorder) to 3.05 (95% CI 1.92–4.86; three or more moves and bipolar disorder).ConclusionsAssociations of mobility with schizophrenia, bipolar disorder and depression do not appear to be attributable to genetic liability as measured here. Potential familial confounding of mobility associations may be predominantly environmental in nature.
Multicenter Evaluation of the Quantra QPlus System in Adult Patients Undergoing Major Surgical Procedures
Authors: Groves Danja S. , Welsby Ian J. , Naik Bhiken I. , Tanaka Kenichi , Hauck Jennifer N. , Greenberg Charles S. , Winegar Deborah A. , Viola Francesco 
Published: February 2020

BACKGROUND:
The management of perioperative bleeding and the optimization of the available therapies are subjects of significant clinical interest. Clinical guidelines recommend the use of whole blood viscoelastic testing devices to target the utilization of blood products during major surgical procedures. The Quantra QPlus System is a new cartridge-based viscoelastic testing device based on an innovative ultrasound technology. The aim of this study was to evaluate this new system in a surgical population.

METHODS:
Two hundred seventy-seven adult subjects were enrolled in a multicenter, prospective observational study consisting primarily of patients undergoing cardiac and major orthopedic surgeries. Samples were obtained at multiple time points for testing on the Quantra QPlus System, the rotational thromboelastometry (ROTEM) delta, and standard coagulation tests. Quantra measurements included Clot Time (CT), Heparinase Clot Time (CTH), Clot Time Ratio (CTR), Clot Stiffness (CS), Fibrinogen (FCS), and Platelet (PCS) Contributions to CS. Data analyses included assessment of the concordance of Quantra parameters with a series of clinical composite indexes formed on the basis of standard coagulation tests in 3 domains representing increased, decreased, and normal/subclinical coagulation function. Linear regression and receiver operator characteristic (ROC) analyses of Quantra parameters with corresponding parameters from ROTEM assays were also performed.

RESULTS:
The accuracy (overall percent agreement or ratio of true positives and true negatives over the entire population) between the Quantra and the composite indexes was between 72% and 98% depending on the specific parameter. Linear regression analysis indicated that the correlation between ROTEM delta and Quantra was very strong with r values ranging between 0.84 and 0.89. Results from ROC analysis demonstrated sensitivities and specificities in the 80%–90% range when QPlus parameters were used to discriminate ROTEM threshold values currently used in goal-directed treatment algorithms.

CONCLUSIONS:
This study demonstrated that the Quantra QPlus System is strongly correlated with a well-established viscoelastic testing device and its parameters effectively represent the results from multiple standard laboratory assays. The Quantra has been designed to operate at the point of care with the potential to provide rapid and comprehensive results to aid in the management of coagulopathic patients.
Decline of Pediatric Ambulatory Surgery Cases Performed at Florida General Hospitals Between 2010 and 2018: An Historical Cohort Study
Authors: Dexter Franklin , Epstein Richard H. , Rodriguez Luis I. 
Published: February 2020

BACKGROUND:
In the province of Ontario, nonphysiologically complex surgical procedures have increased at 4 pediatric hospitals with a reciprocal decline among the other (general) hospitals performing pediatric surgery. Given the differences between the Canadian and US health systems, we studied whether a similar shift occurred in the state of Florida and examined the age dependence of the shift.

METHODS:
We used outpatient pediatric surgery data from all nonfederal hospitals, hospital-owned facilities, and independent ambulatory surgery centers in Florida, 2010–2018. Inferential analyses were performed comparing 2010–2011 with 2017–2018. Annual caseloads are reported as cases per workday by dividing by 250 workdays per year.

RESULTS:
Statewide, comparing 2010–2011 with 2017–2018, among children 1–17 years, pediatric hospitals’ caseload increased overall by 50.7 cases per workday, overall meaning collectively among all hospitals combined. The caseload at general hospitals and ambulatory surgery centers, combined, decreased by 97.7 cases per workday. The general hospitals performed 54.7 fewer cases per workday. Among the 112 general hospitals, the mean pairwise decline was −0.49 cases per workday (99% confidence interval, −0.87 to −0.10; P < .0001). The changes were due to multiple categories of procedures, not just a few.
Comparing 2010–2011 with 2017–2018, among 3 age cohorts (1–5, 6–12, and 13–17 years), the pediatric hospitals, statewide, performed overall 16.2, 15.1, and 19.3 more cases per workday, respectively. The general hospitals and ambulatory surgery centers, combined, performed fewer cases per workday for each cohort: 49.4, 21.4, and 26.9, respectively. The general hospitals overall performed fewer cases per workday for each cohort: 27.3, 12.1, and 15.4, respectively. Among general hospitals, the mean pairwise difference in the declines between patients 1–5 years vs 6–17 years was 0.00 cases per workday (99% confidence interval, −0.13 to +0.14).

CONCLUSIONS:
The decline across all age groups was inconsistent with multiple general hospitals increasing their minimum age threshold for surgical patients because, otherwise, the younger patients would have accounted for a larger share of the decreases in caseload. Pediatric hospitals and their anesthesiologists have greater surgical growth than expected from population demographics. Many general hospitals can expect either needing fewer pediatric anesthesiologists or that their pediatric anesthesiologists, who also care for adults, will have smaller proportions of pediatric patients in their practices.
Optimizing Health, Wellness, and Performance of the Tactical Athlete
Authors: Wise Sean R. , Trigg Steven D. 
Published: February 2020

Abstract
Tactical athletes are individuals in service occupations with significant physical fitness and performance requirements such as law enforcement, firefighters, emergency responders, and military service members. Tactical athletes also may have specific administrative requirements related to documenting physical injuries. Musculoskeletal injuries are a large burden on the tactical athlete population, with incident rates varying based on the specific profession. Chronic exertional compartment syndrome (CECS) is difficult to manage in the tactical athlete population due to their limited ability to reduce impact activities and poor surgical outcomes. Botulinum neurotoxin-A and gait retraining show promise as alternative treatments for CECS. Heat injuries are frequent in the tactical athlete populations, and a graduated return to play process helps to prevent morbidity. Management of musculoskeletal injuries in tactical athletes requires consideration of operational schedules and adequate reconditioning, in addition to traditional injury evaluation.
Is the Normal Shoulder Rotation Strength Ratio Altered in Elite Swimmers?
Authors: BOETTCHER CRAIG , HALAKI MARK , HOLT KYLIE , GINN KAREN A. 
Published: February 2020

ABSTRACT

Introduction
It is commonly believed that the shoulder external rotation (ER) to internal rotation (IR) strength ratio is decreased in swimmers due to predominant IR loading during the pull-through (propulsive) phase which predisposes to shoulder pain. However, the evidence supporting this hypothesis is inconclusive. Therefore, the aim of this study was to examine shoulder rotation strength parameters in elite swimmers and investigate potential associations with shoulder pain.

Methods
Sixty-eight (40 men; age, 19.9 ± 3.2 yr) elite swimmers provided demographic and shoulder pain history data before measurement of shoulder rotation strength. Mixed model analyses were used to examine differences in shoulder IR and ER strength normalized to body weight (BW) and the shoulder rotation strength ratio. A multinomial logistic regression model was utilized to examine associations between shoulder rotation strength parameters and shoulder pain.

Results
Mean shoulder IR strength (BW) was approximately 0.29 for male swimmers and 0.26 for female swimmers. Mean shoulder ER strength (BW) was approximately 0.19 for male swimmers and 0.18 for female swimmer. The shoulder ER/IR strength ratio was approximately 0.70 bilaterally for all swimmers. There were no significant differences between dominant and nondominant shoulders in IR or ER strength normalized to BW (P ≥ 0.547). There were no associations between any shoulder strength parameters and shoulder pain (r
2 = 0.032, P = 0.107).

Conclusions
Despite the high IR loading, optimal swimming technique does not alter the normal ER/IR strength ratio at the shoulder. Elite swimmers who report current or a history of shoulder pain demonstrate normal shoulder rotation strength ratios. The finding of symmetrical shoulder rotation strength points to side-to-side strength comparisons as a valuable clinical tool in managing swimmers with unilateral shoulder pain.