bluuebunny/crossref_metadata_2025_split huggingface dataset:
KORELASI GLUKOSA DAN KETON DARAH PADA PASIEN UNIT GAWAT DARURAT DAN RAWAT INAP PENDERITA DIABETES MELITUS TIPE 2 DI RSAU DR. ESNAWAN ANTARIKSA JAKARTA
Authors: Susanti Ellis , Masita Dara , Latifah Imas 
Published: November 2019

Secara epidemiologi diperkirakan pada tahun 2030 prevalensi Diabetes Melitus (DM) di Indonesia mencapai 21,3 juta orang. Berdasarkan hasil Riset Kesehatan Dasar tahun 2013, prevalensi DM tertinggi terdapat di Yogyakarta (2,6%), DKI Jakarta (2,5%) dan Sulawesi Utara (2,4%). Diabetes melitus merupakan penyakit kronik yang menyebabkan gangguan pada metabolisme, disebabkan kurangnya produksi insulin yang diperlukan dalam proses perubahan glukosa menjadi energi. Ketika tubuh tidak memiliki cukup glukosa, hati mengubah lemak menjadi keton. Berlebihnya keton yang ada di dalam darah disebut ketosis. Diabetes melitus tipe 2 paling banyak ditemukan di masyarakat. Terjadinya ketosis dan kemudian asidosis dapat menyebabkan kegawatan pada penyandang DM (ketoasidosis). Tujuan dilakukannya penelitian ini untuk mengetahui tingkat ketoasidosis pada pasien DM tipe 2 di unit gawat daraurat (UGD) dan rawat inap sehingga penanganannya dapat lebih tepat. Metode yang dilakukan yaitu observasi potong lintang, subyek penelitian sebanyak 86 orang DM tipe 2 di UGD dan rawat inap berdasarkan rekam medik. Hasil yang diperoleh korelasi lemah (r= 0,352, p= 0,007) pada pasien UGD dan korelasi cukup (r= 0,570, p= 0,001) pada pasien rawat inap. Pada pasien UGD tidak mengalami ketoasi dosis berat dibandingkan dengan pasien rawat inap, antara lain berhubungan dengan durasi patofisiologi. Kesimpulan dan Saran yaitu pasien rawat inap harus dilakukan penatalaksanaan ketoasidosis yang lebih tepat. Kata Kunci: DM tipe 2, Glukosa, Keton, Ketoasidosis
Bradycardia in elderly patient: look at the body temperature
Authors: Sforza Alfonso , Carlino Maria Viviana , Mancusi Costantino , Catapano Emanuela , Castellano Graziella , Costanzo Anita , Luiso Vittorio , Izzo Arturo , Guarino Mario 
Published: November 2019

ABSTRACT
We describe a case of a 83-year-old man who presented to the Emergency Department for bradycardia and reduced level of consciousness. His conditions had progressively worsened in the last few days and bradycardia induced his relatives to call on emergency team. He presented with hypoxia, cough, bradycardia and a reduced Glasgow Coma Scale value. The body temperature was not detected by standard thermometer and the electrocardiogram showed sinus bradycardia with prominent Osborne wave in the lateral precordial leads. His rectal temperature was 30.1 °C and the diagnostic work up showed a right lung pneumonia. He underwent active and passive rewarming treatment and sepsis treatment. Electrocardiographic abnormalities disappeared after rewarming and the patient was admitted to sub-intensive care unit.
Consensus document ANMCO/FADOI/SIAARTI/SIC/SIMG/SIMI/SIMEU: The clinical-diagnostic and therapeutic pathway of patients with acute heart failure in the Emergency Department
Authors: Vescovo Mariavittoria 
Published: November 2019

Acute heart failure (HF) involves hospitals throughout the world and, as well as other acute cardiac pathologies such as coronary syndromes, has markedly unfavorable outcomes: the mortality or rehospitalization rate after 3 months is 33%, mortality 1 year after admission varies between 25% and 50%.
A critical factor in managing acute HF is the multiplicity of health professionals involved in the diagnostic-therapeutic pathway of this syndrome - general practitioners, emergency doctors, cardiologists, internists, anesthesiologists/resuscitators - and therefore also the need to integrate different knowledge and skills and converge on care goals that can improve clinical outcomes.
This consensus document originates from the joint work of the Scientific Societies, representing various professional figures involved in assisting patients with acute HF, and has shared strategies and pathways aimed at guaranteeing both quality care levels and better outcomes. The document details the entire journey of the patient with acute HF from the onset of symptoms at home, diagnosis, home management or sending to the Accident and Emergency/Emergency Admissions Department (AandE/EAD), mode of transport, early therapy, through the instrumental clinical pathways for diagnosis in AandE/EAD and the treatment, risk stratification and discharge of the patient in ordinary hospitalization or at home. It also analyses the possible role of cardiological "fast-track", Short Intensive Observation and regional welfare taking charge through general medicine and specialist clinics for the care of HF.
The growing care burden and the complex problems generated by acute HF cannot find an adequate solution without an integrated multidisciplinary approach that effectively places emergency facilities in the network along with intensive and ordinary hospitalization units and within the context of regional care. Thanks to contributions from the most qualified Scientific Societies, this document pursues this objective by proposing a structured, shared and applicable pathway which can contribute to manage a widespread problem in the country.
Il clustering diseases in medicina interna come strumento di approccio alla complessità dei pazienti?
Authors: Tangianu Guest Editors: Flavio , Nardi Roberto 
Published: November 2019

IL CLUSTERING DISEASES IN MEDICINA INTERNA
Co-morbilità, multi-morbilità, associazioni di malattie e complessità in Medicina Interna F. Tangianu, P. Gnerre, M. La Regina, F. Berti, G. Scanelli, F. Colombo, G. Pinna, R. Nardi Fragilità, disabilità e gruppi di malattie associate A. Marengoni, A. Zucchelli, D.L. Vetrano, G. Onder, A. Nobili
MALATTIE INDICE E CLUSTERING DISEASES IN MEDICINA INTERNA
Fibrillazione atriale e clustering diseases C. Tieri Ipertensione arteriosa e clustering diseases A. Abenante, F. Tangianu Clustering diseases e scompenso cardiaco N. Tarquinio Diabete-obesità-sindrome metabolica e clustering diseases E. Barbagelata, I. Ambrosino, M. Poggiano Iperuricemia e gotta M. Giuliani, A. Cerasari, L. Sanesi Ictus ischemico T. Ciarambino Demenza e clustering diseases C.A. Usai, A. Filippi Depressione come malattia sistemica D. Tirotta Trombo-embolismo venoso M. Gino, F. Pasin Broncopneumopatia cronica ostruttiva e clustering diseases O. Para, M. Ronchetti Insufficienza renale cronica A. Bianco Anemia C. Zaninetti Cirrosi epatica G.A. Vassallo, V.A. Vassallo, C. Tarli, F. Bernardini, S. Rotunno Artrite reumatoide: clustering diseases A. Tamburello, L. Castelnovo, P. Faggioli Psoriasi: punta d’iceberg di malattie associate o sottese A. Guastalla Clustering diseases delle neoplasie P. Crispino, D. Colarusso
CONCLUSIONI
Multimorbilità, clustering diseases e politerapia: criteri di appropriatezza prescrittiva A. Nobili, F. Croset, A. Marengoni, P.M. Mannucci
Adoption of Recommended Bio-fertilizer Technologies among Soybean Growers in Ujjain Distrsict of Madhya Pradesh
Authors: Patidar Vaijanti , Choudhary Sandhya , Wankhede Abhay , Choudhary S. K. 
Published: November 2019

Bio-fertilizers are living organisms that enrich the nutrient quality of the soil. It refers to the use of microbes instead of chemicals to enhance the nutrition of the soil. Conventional fertilizers are those formed through decomposition including compost; household wastes and green manure while chemical fertilizers are manmade or mined. Convention fertilizers are nature friendly but not effective as chemical fertilizers. Conventional or natural fertilizers provide nutrient to plant at slow rate and lower concentration but chemical fertilizers provide nutrient at fast rate and higher concentraion so, farmers frequently try to use chemical fertilizers in the field for crop development. Ujjain district has a high potential for soybean production. The crop is processed for oil, protein and animal feed. A smaller percentage is processed into soy milk, soy flour, soy protein, tofu for human consumption. The higher use of chemical fertilizers in soybean crop for higher yield creates negative effect on human, animal and environment health. Hence, research in the use of bio-fertilizer in soybean crop in Ujjain district was conducted with 120 respondents. The major finding (e.g. quantity or bifertilizer used as seed trement) was obtained as Adoption of recommended bio-fertilizer technologies by beneficiary farmers was higher than non beneficiary farmers.
Production and Application of No-purified Rhamnolipids in the Soil-washing of TPHs Contaminated Soils
Authors: G. Torres Luis , González Roberto , Gracida Jorge 
Published: November 2019

Aims: This work aimed to demonstrate the feasibility of producing (mono- and di-) rhamnolipids employing a strain of Pseudomonas aeruginosa strain ATCC 9027 employing olive oil as a substrate and some mineral salts. This rhamnolipid is a biosurfactants with multiple applications The CMC of this product under different conditions (filtered, unfiltered, in the presence and absence of Fe and Mg, at different pH values) was assessed. At the end, the UP was assessed in the washing of a TPH contaminated soil.
Place and Duration of Study: Bioprocess department. Unidad Profesional Interdisciplinaria de Biotecnologia-IPN facilities, during 2016.
Methodology: Rhamnolipids were produced with P. aeruginosa in olive oil, then by drying the culture broth was generated an unpurified product (UP) that contained 0.19% rhamnolipids. Critical micelle concentration CMC of UP products were evaluated in the presence of Ca2+ or Fe3+ from 0.5 to 2 mM, and pH values from 4 to 10. Finally, this surfactant was assessed in the washing of hydrocarbon-contaminated soils, and compared with other synthetic surfactants.
Results: It was found that CMCs were similar to those reported in the literature for pure rhamnolipids. The UP products have shown dynamic behavior in the soil washing at concentrations below 176 mg/L because removed 80% of 6,500 mg TPH/Kg from a gravel-sandy soil; the rhamnolipids could be removed TPH through mobilization mechanism.
Conclusion: It was possible to produce rhamnolipid using olive oil as carbon source and strain of P. aeruginosa ATCC 9027 to levels of 100 mg/L. It was feasible to produce a powder containing 1.19% of rhamnolipids. The UP had better properties as a surfactant than the purified product. The pH affects the CMC of the rhamnolipids in a way that promotes their behavior as ionic surfactant or nonionic surfactant. The ionic strength with Ca 2+ and Fe3+ has an effect on the CMC of rhamnolipids so that the decreases in the range of 35 to 41 mg/L in the presence of 0.5 to 2 mM of metals. The UP rhamnolipids were employed for washing soil contaminated with 6,500 mg/kg increased TPH removal at low concentrations and to be as effective as chemical surfactants. TPH removal observed was about 80% for rhamnolipid with a CMC x 0.074 concentration.
Critical Moisture Content, Bulk Density Relationships and Compaction of Cultivated and Uncultivated Soils in the Humid Tropics
Authors: Etim Udom Bassey , Ehilegbu Joy 
Published: November 2019

Soil compaction affects soil fertility through increasing bulk density and soil strength. It also decreases infiltration rate, total porosity and amount of water stored in the root zone for crop use. In this study, we evaluated the optimum moisture contents (OMC) in relation to maximum dry density (MDD) and compaction of cultivated and uncultivated soils. The study was carried out on four land use types viz: uncultivated: Velvet tamarind (Dialium quineese), rubber plantation (Hevea brasiliensis) and cultivated: 5-year fallow and 10-year continuous cultivated soil to maize crop. Proctor test for the maximum dry density-moisture content relationship was carried out, including some hydraulic and structural properties of the soil, and their effect soil compaction. Results showed that optimum moisture content (OMC) for compaction relate to the maximum dry density (MDD). In which case, dry density increased with water content to a maximum and decrease as moisture content increased above the optimum. Soil organic matter (SOM) content and particle size distribution highly affected the MDD and OMC. The MDD and OMC were: 1.92 g cm-3 and 10.4%, 1.95 g cm-3 and 11.2%, 1.91 g cm-3 and 12.3%, and 1.87 g cm-3 and 12.8% for velvet tamarind, 5-year fallow, CC and rubber plantation soils respectively, at 0-15 cm depth. Changes in field bulk densities at similar depths were in the order of velvet tamarind < rubber < 5-year fallow < CC. There were highly significant (p < 0.01) relationships between MDD, total porosity, Ksat and SOM and negative relationships between these parameters and OMC. Thus, continuous cultivation increased MDD and reduced OMC for compaction. Two- season fallow periods with legume could improve soil hydraulic properties and maintain the MDD of sandy soils at minimum.
Impact of Irrigation Intervals on the Yield and Quality of Lupine (Lupinus termis L.) Grown in Sandy Soil Amended by an Organic Amendment
Authors: T. Rashad Rama , H. A. El-Agyzy Fatma , M. Abdel-Azeem Seham 
Published: November 2019

Aims: Two field experiments have been carried out to study the effect of different irrigation periods in the presence of compost as an organic amendment on the yield and quality of lupine (Lupinus termis L.) under the sandy soil conditions.
Study Design: Split-plot design.
Place and Duration of Study: The successive winter seasons of 2016/2017 and 2017/2018 at the Ismailia Agricultural Research Station, (30°35'30" N 32°14'50" E elevation 3 m), Agricultural Research Center (ARC), Egypt.
Methodology: Compost has been applied at the rates of 11.90, 23.81 and 35.71 ton/ha before planting. Three irrigation intervals were assigned after planting by 3, 6, and 9 days; the applied water volume for each was 4761.91 m3/ha.
Results: After harvesting, some parameters were estimated. As the compost rates increased, the soil EC significantly decreased while the available N, P, K, and Fe were significantly increased by 9.51, 12.79, 5.17, and 5.8%, respectively. For same compost rate, the irrigation intervals (3, 6, and 9 days) significantly decreased the available N relatively by 2.88, 5.16, and 6.96%, respectively and the available K by 3.45, 5.06, and 4.37%, respectively. The 6 days interval showed that most significant increase in the seeds' content of nutrients at different compost rates and the seed yield has increased by 19.59, 22.31, and 21.88% for the compost rates of 11.90, 23.81, and 35.71 ton/ha, respectively. The relative increase was by 20.48, 7.63, 4.49, 10.89, and 14.92% for the crude protein, crude lipids, total ash, TSS and the amino acids, respectively. The effect of treatments on the relative shoot moisture (%) and the field water use efficiency (F.W.U.E.) (kg/m3) was discussed.
Conclusion: The 6 days irrigation interval along with a compost application rate of 23.81 ton/ha can be recommended for lupine grown in sandy soil as they showed the most significant increase in the nutrients content of seeds by 22.31%.
Rural Communities’ Perceptions of Climate Change and Its Impacts on Their Livelihood in Southeastern Niger
Authors: Issaharou-Matchi I. , Rabiou H. , Mahamane M. , Idrissa B. , Mahamane A. , Saadou M. 
Published: November 2019

Climate change exacerbates ecosystem degradation in Sahel where rural communities are highly dependent on natural resources and ecosystem services for their livelihoods. In order cope with the adverse effects of climate change by developing climate adaptation strategies, there has been a need to understand how communities perceive the change or variability in their local climate and how this change could affect their livelihood. This paper aims to examined rural communities’ perceptions about climate change in the commune of Chetimari located in the region of Diffa, southeastern Niger. It investigated particularly: 1) how communities’ perceptions of climate change? 2) What are the impacts of climate change on the livelihood of communities? And 3) What do elements and options to detect abrupt change points in annual precipitations and both annual maximum and minimum temperature? Survey data were collected from October to November 2018 from 101 households (15% of the total households in the study area) in three villages. Multiple correspondence Analysis (MCA) and Factorial Correspondence Analysis (FCA) were performed with XLSTAT to analyzed data from survey. Meteorological data including Monthly precipitation from 1981 to 2017, and Monthly temperatures (maximum, minimum) from 1986 to 2017 of the Diffa meteorological station were analyzed using R to perform the Man Kendal trend test and the Pettit test for detection of abrupt changes in the series. Results showed that community perceptions on temperature increase (not for precipitation) trends as indicators of climate change are in agreement with meteorologically observed trends. The findings showed that people in this zone are aware of climate change that they see as increase in maximum and minimum temperature, decrease in rainfall, frequency of extreme events (drought and flood), dry spells, decrease in number of rainy days, strong winds etc…Results revealed the most significant impacts of climate change affecting the livelihood of rural communities in this area. These are higher risk of crop damage from drought, farmer and herder conflict frequency, drying up of wells, food shortage/insecurity, silting pools, decline in soil fertility and livestock production, silting pasture areas, frequency of livestock diseases, increased weed and invasive species, livestock mortality. The perception of the climate change and its impacts on the main socioeconomic activities vary from a village to another, according the sexes and age ranges.
We conclude that communities are relatively aware about the climate change issue. For a better management of climate-induced risks in the study area we stress the need to improve the awareness of climate change within the rural community by improving the availability and the quality of relevant climate information.
Prevalence of Intestinal Helminthic Infections in Pregnant Women Attending Antenatal Clinic in Abeokuta, Nigeria
Authors: A. Adedotun A. , A. Awoyemi O. , A. Osiyemi J. , Popoola I. , A. Daramola A. , O. Osiyemi E. 
Published: November 2019

Intestinal infections during pregnancies are recorded with common factors which include prenatal mortality, poor nutritional status, impaired growth, low birth weight, anaemia and disease burden. It is one of the major public health problems in developing nations.
This survey was carried out with 100 pregnant women attending Oba Ademola II Maternity Hospital, Ijemo, Abeokuta, within six months to determine the infection prevalence, intensity, risk factors and packed cell volume (PCV) correlation. Determination of helminth was done by formo-ether sedimentation technique. Structured questionnaire was applied and analyzed using Analysis of variance (ANOVA).
Results revealed the prevalence of Hookworm to be 18%, while that of Ascaris was 50%. Comparison of age between 18-45 years old and level of education was also taken into consideration.
Personal hygiene was significantly associated with reduced likelihood of infection. From this study, it is evident that helminthic infections were prevalent among pregnant women. It is therefore recommended that antenatal clinics should incorporate routine stool examination for pregnant women to detect parasitic worms and refer positive cases for medical treatment and routine deworming of all pregnant women after the first trimester should also be encouraged.
Antimicrobial Efficacy of Chromolaena odorata Extract against Bacteria Isolated from Patients with Urinary Tract Infection in Ondo State, Nigeria
Authors: Okhonlaye Ojokoh Anthony , Mogaji Olumide , Saanu Adeleke Bartholomew 
Published: November 2019

Aim: This study is designed to isolate and identify the microorganisms associated with urinary tract infection in infected patients, determine the antimicrobial resistance pattern on the microbial isolates and the antimicrobial efficacy of solvents leaf extract of Chromolaena odorata on the resistant isolates.
Methodology: Six hundred (600) mid-stream urine samples were collected from infected patients in some selected hospitals in Ondo State. The phytochemical screening of the plant was determined. The antibiotics sensitivity and antimicrobial activity of the plant extract was determined using plate assay and agar well diffusion methods.
Results: Out of 600 urine samples analyzed, 472 (78.68%) showed significant growth of uropathogens comprising 197 (32.80%) male and 275 (45.83%) female. The isolated microorganisms comprise 5 Gram-positive bacteria (GPB), 9 Gram-negative bacteria (GNB) and 4 Candida sp. GNB account for 284(58.79%), GPB 158(32.71%) and Candida sp 41(8.48%). Escherichia coli showed high prevalence 90(18.63%) while Klebsiella ozaenae showed the least 11(2.27%). The phytochemical constituents of C. odorata extracts contained tannins, flavonoids, saponins, steroids and terpernoids and bacterial isolates showed resistant to all the antibiotics. Pseudomonas mendocina and P. putida showed the least resistant to C. odorata extracts. The MIC of the leaf extracts ranged from 5.0 mg/ml to 50.0 mg/ml. The methanol extract had the highest antimicrobial activity than n-hexane and chloroform extracts on the uropathogens.
Conclusion: The high therapeutic potentials of C. odorata extract against the uropathogens could be used as alternative phytotherapy in herbal medicine to the commercial antibiotics in the treatment of urinary tract infections.
Plasmid Profile Analysis of Multi-drug Resistant Proteus spp isolated from Patients with Wound Infection in Northeastern Nigeria
Authors: M. Tom Isyaka , B. Agbo E. , A. Faruk Umar , M. Ibrahim Muhammad , M. Umoru Askira , B. Umar Jidda , Aliyu Abdullahi , B. Haruna Ali 
Published: November 2019

Aims: We analysed the prevalence of plasmid mediated multidrug resistance among Proteus spp isolated from wound infection patients attending healthcare centers in Maiduguri.
Methodology: 320 wound swab samples were collected from August 2016 to June 2017, and investigated via microscopy, cultured on Blood agar and MacConkey agar. Suspected Proteus spp isolates were further confirmed using biochemical tests. Kirby bauer disc diffusion test was used to determine the antimicrobial susceptibility pattern. Isolates confirmed to be multidrug resistant (MDR) were subjected to gel electrophoresis for the determination of plasmid profile.
Results: Twenty eight (28) samples yielded Proteus spp, giving a prevalence rate of 8.75%. Proteus mirabilis was the most significant specie isolated (32.14%). Isolates were most sensitive/least resistant to Ciprofloxacin (85.71%/14.29%) and most resistant/least sensitive to Augmentin (10.71%/89.29%). 64.28% of isolates observed were MDR strains and were quite significant among patients between the ages of 21-30years (21.43%). MDR Proteus mirabilis was most the significant and highly prevalent among patients suffering from wound sepsis and burns (10.71% respectively). The association between MDR Proteus spp and wound types was statistically not significant (X2 =7.342, p>0.01). Plasmid profile analysis revealed that 72.22% of the MDR isolates harbour plasmids with a DNA fragment size of 100 bp and a molecular weight of 31ng/10µl. An average of 7.22% of MDR isolates were cured of their plasmids while an average of 56.67% of MDR isolates resisted curing.
Conclusion: Here, we report a high prevalence of multidrug resistance and a high rate of plasmid carrying strains of Proteus spp in wounds of hospitalised patients. We suggest that there is a role played by plasmid in the mediation of multidrug resistance among the MDR Proteus spp isolated, where the majority of the MDR isolates observed carry plasmids.