bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Stress-Similarity Triggering Model for Aftershocks of the Mw 6.4 and 7.1 Ridgecrest Earthquakes
Authors: Hardebeck Jeanne L. 
Published: June 2020

ABSTRACTThe July 2019 Mw 6.4 and 7.1 Ridgecrest earthquakes triggered numerous aftershocks, including clusters of off-fault aftershocks in an extensional stepover of the Garlock fault, near the town of Olancha, and near Panamint Valley. The locations of the off-fault aftershocks are consistent with the stress-similarity model of triggering, which hypothesizes that aftershocks preferentially occur in areas where the mainshock static stress change tensor is similar in orientation to the background stress tensor. The background stress field is determined from the inversion of earthquake focal mechanisms, with the spatial resolution adapted to the local density of earthquakes. The mainshock static stress change is computed using finite-source models for the Mw 6.4 foreshock and Mw 7.1 mainshock. I quantify the similarity between these two stress fields using the tensor dot product of the normalized deviatoric stress tensors. The off-fault aftershocks in the Garlock stepover and the Olancha area fall within lobes of positive stress similarity, whereas the aftershocks near Panamint Valley are partially within a lobe. The cluster in the Garlock fault stepover and the smaller of two clusters near Olancha occur in regions of locally anomalous background stress that results in higher stress similarity. I compute the spatial density of M≥2.0 aftershocks and find that the aftershock density increases as a function of stress similarity, with a factor of ∼15 difference between high stress-similarity and low stress-similarity areas. This result is robust with respect to the choice of mainshock model and the uncertainty of the background stress field. The aftershock density varies substantially inside the high stress-similarity lobes, however, indicating that other variable background conditions, such as material properties, temperature, and fluid pressure, may also be playing a role. Specifically, temperature and fluid pressure conditions might help explain the low rate of aftershocks in the Coso geothermal field.
Seismicity Rate Change at the Coso Geothermal Field Following the July 2019 Ridgecrest Earthquakes
Authors: Kaven J. Ole 
Published: June 2020

ABSTRACTMany geothermal and volcanic regions experience remote and regional triggering following large earthquakes. The transient or permanent changes in stresses acting on faults and fractures can lead to changes in seismicity rates following either the passage of teleseismic waves or the permanent change in stresses following regional events. One such region of prevalent triggering is the Coso Geothermal Field (CGF) in eastern California, which is located roughly 30 km to the north of the 2019 Mw 7.1 Ridgecrest epicenter. Previous regional earthquakes have not only seemingly caused increase in seismicity rate surrounding the CGF, but also showed an absence of such rate increases in the CGF itself. To test whether seismicity rates in the CGF were dissimilar to the surrounding area following the Mw 7.1 Ridgecrest earthquake, I carry out seismicity rate change calculations using a catalog of seismicity compiled using a local seismic network and find that the behavior at CGF is identical to the surrounding area. Comparisons of seismicity rate changes calculated using a regional-network-derived catalog, and the local-network-derived catalog show that for a moderate, regional earthquake (2009 Mw 5.2 Olancha, California), the local network catalog reveals a change in seismicity rate whereas the regionally network catalog shows no significant changes. The differences are possibly related to incomplete sampling of seismicity using the regional network due to the existence of a shallow brittle–ductile transition centered on the CGF. The CGF, thus, is prone to triggering from both teleseismic and regional earthquakes.
Diabetes y embarazo
Authors: Peláez Vallejo Jorge Elías 
Published: June 2020

El manejo de la diabética embarazada ha sufrido modificaciones a través del tiempo debido al mejor conocimiento de su fisiopatolog ía . A pesar de una incidencia de sólo 1.02% (Raymond Corwin), las complicaciones que esta patología ocasiona al binomio madre - feto son importantes, hecho que ha llevado a las diferentes escuelas a profundizar sobre el tema con el fin de realizar un adecuado manejo tendiente a disminuirlas, objetivo que se ha logrado especialmente en la mortalidad perinatal y un poco menos en la morbilidad.
Tratamiento de la pre-eclampsia grave y de la eclampsia. Estudio prospectivo
Authors: Jubiz H. Alfonso , Mejía V. William 
Published: June 2020

Se estudiaron tres grupos de embarazadas que presentaron pre-eclampsia grave y eclampsia . En el grupo I se utilizó como tratamiento el Sulfato de Magnesio en el II, la Hidralacina más el Sulfato y en el grupo III la Hidralacina sola. El 70% de las gestantes ingresaron con embarazo de término. El 26.7% presentaron eclampsia y las restantes (73.3%) pre-eclampsia grave . El 60% de los embarazos terminaron por cesárea. Al efectuar las pruebas estadísticas se observa una diferencia significativa entre la Hidralacina (grupo III) y los otros dos grupos con una p < 0.05. La Hidralacina utilizada a la dosis de 20 mgs produce una disminución de la tensión arterial diastólica más rápida y este efecto es más sostenido.
Monitoría fetal anteparto en la unidad de alto riesgo del Hospital San Ignacio
Authors: Medina Murillo Jorge E. , Bechara Chamat Jaime 
Published: June 2020

Se presenta el resultado de 259 pruebas, 205 pruebas de NST y 54 de PTC, efectuadas en 162 pacientes clasificadas como de alto riesgo en el Departamento de Gineco-obstetricia del Hospital San Ignacio.La patología preponderante fueron los desórdenes hipertenslvos 55% (N:89). El 71.2% (N: 146) de las pruebas de NST fueron reactivas y el 28.8% (N: 59) fueron no reactivas; de estas 54 se les practicó PTC: 79.6 (N: 43) fueron negativas, el 16.6% (N:9) fueron positivas y el 3.8% (2) fueron equívocas.Hubo tres muertes perinatales: dos ocurrieron en pacientes que tenían PTC positiva y en la otra aunque la PTC fue negativa, había transcurrido más de una semana entre la ejecución de la prueba y el parto.Se relaciona el resultado final del embarazo (peso, semanas de gestación y Apgar) con las pruebas empleadas, encontrándose que existe una correlación entre la PTC positiva y la mortalidad perinatal, el peso más bajo al nacimiento, el índice de Apgar más bajo y el posible retardo del crecimiento intrauterino en estas pacientes.Se confirma la utilidad pronostica de la monitoria fetal anteparto en pacientes de alto riesgo.
Incidencia del cáncer de vulva. Hospital Universitario San Vicente de Paúl 1972-1982
Authors: Gallego Noreña Gildardo 
Published: June 2020

Se realiza una revisión de 10 años, entre el 1o. de mayo de 1972 y el 1o. de junio de 1982, de pacientes atendidas en la sección Oncología-Ginecología del Depto. de Obstetricia y Ginecología de la Facultad de Medicina de la Universidad de Antioquia que tienen diagnóstico histológico comprobado de cáncer vulvar; se revisan 41 casos, se analiza incidencia anual 4.1 casos por año. Se encontró porcentaje considerable en edad entre 41 y 71 años. Predominio histológico del carcinoma epidemoide. Se hizo énfasis en el tratamiento quirúrgico, se analizan técnicas y se estudió el seguimiento de pacientes,encontrándose pacientes vivas en control 29.2%; se sacan conclusiones de mejorar el seguimiento de las pacientes.
Prueba electrónica anteparto de vitalidad fetal
Authors: Restrepo Salazar Jorge A. , Awad Zainete Eva María , Uribe Vargas Luis Fernando , Júbiz Hasbun Alfonso 
Published: June 2020

Se analizaron 1.053 registros anteparto de pacientes con factores de riesgo perinatal y se seleccionaron 435 correspondientes al último control realizado durante la consulta prenatal. El 84.4% de los registros fueron clasificados como reactivos, 7.2% no reactivos con hipoxia, 3.6% no reactivos y 1.2% sinusoidal.En el grupo de registros reactivos el 97% de los recién nacidos presentaron un Apgar de 7 o más a los cinco minutos. En los no reactivos el 92% estaban vigorosos a los cinco minutos. Cuando la desaceleración estuvo presente en el registro nc reactivo, sólo el 69.6% de los neonatos se encontraron vigorosos a los cinco minutos. En los 5 trazados sinusoidales sólo un recién nacido se encontró vigoroso a los cinco minutos y todos murieron en las primeras 48 horas.1. La prueba sin estímulo reactiva se correlacionó con el estado del neonato, al primero y al quinto minuto, y a las 48 horas.2.Cuando el registro es clasificado como no reactivo, debe continuarse la estimulación con oxitocina.3.En los registros no reactivos, cuando se sobrepone la desaceleración variable el resultado perinatal es pobre (69%).4.El trazado de tipo sinusoidal predice un resultado perinatal malo y se encuentra especialmente en la ¡soinmunización al factor Rh.
Inventario de gases de efecto invernadero: Distrito central de Puntarenas (Costa Rica)
Authors: Porras-Rozas Ariel , Medina-Mora Irene , Castillo-Calderón Valeria , Espinoza-Ocampo Ana 
Published: June 2020

En el 2018 el MINAE (Ministerio de Ambiente y Energía de Costa Rica) oficializó el PPCN 2.0, en respuesta a la Estrategia Nacional de Cambio Climático. En el distrito central de Puntarenas, la UTN lidera los esfuerzos para la elaboración de los Inventario de gases de efecto invernadero. Para ello se siguió la metodología descrita en el PPCN 2.0; se calcularon las emisiones del transporte y la energía estacionaria (consumo de combustibles fósiles y electricidad), residuos sólidos y aguas residuales. Para obtener la información requerida, se emitieron solicitudes de información a actores claves del distrito y se aplicó una encuesta al sector residencial y al sector comercial e industrial. Se utilizaron además los factores de emisión y potenciales de calentamiento global del IMN. Finalmente, se obtuvieron emisiones de 83618,27 ton CO2e para el año 2016 y 79053,66 ton CO2e para el año 2017, donde el mayor aporte es representado por el consumo de combustibles fósiles en la actividad pesquera y el transporte.
Między studium a punctum. Spotkania ze sztuką w poetyckiej twórczości Stanisława Ledóchowskiego
Authors: Bajda Justyna 
Published: June 2020

This article discusses ekphrases of the poet, sculptor, stage designer, and art critic Stanisław Ledóchowski, which were published in 2013 in his volume of poetry Liście od Krakowa and in several bibliophile editions of his individual works.
The discussion concerns poems dealing with three forms of art: architecture, sculpture, and painting. Poetic interpretations of works of art were placed in the context of the terms studium and punctum introduced by Roland Barthes to describe the method of finding meaning in art on two levels. The studium concerns generally available cultural context, while the punctum is an often-in-timate encounter of the viewer with an artistic work, which not only reveals the specific aesthetic awareness of the poet but also his individual sensitivity.
Universitarias en el antifranquismo. Mujeres, movilización estudiantil y feminismo, 1960-1975
Authors: Moreno Seco Mónica 
Published: June 2020

La experiencia colectiva de las estudiantes universitarias españolas que se movilizaron contra la dictadura franquista no es muy conocida, a pesar de que en los años sesenta y setenta tuvo lugar el ingreso masivo de mujeres a las aulas universitarias y de que un número destacado de ellas participaron en las protestas, alcanzando en algunos casos puestos de liderazgo. Por otro lado, en el movimiento estudiantil adquirieron una especial relevancia nuevas costumbres y relaciones personales. Por todo ello, nos preguntamos si esta composición más equilibrada y estos nuevos intereses introdujeron cambios o si por el contrario pasaron inadvertidos. Por último, se reflexiona sobre la tensión entre la fantasía de la igualdad y los frecuentes casos de discriminación en el mundo universitario, y sobre cómo influyó la experiencia de la militancia estudiantil en las jóvenes que comenzaron a interesarse por el feminismo y pronto formaron parte de grupos de mujeres. Este texto aborda estas cuestiones desde una perspectiva metodológica que incorpora la intersección entre las categorías de género, edad y clase.
A protocol for Targeted Perturb (TAP)-seq and targeted single-cell RNA-seq
Authors: Schraivogel Daniel , Velten Lars , Gschwind Andreas R. , Steinmetz Lars M. 
Published: June 2020

Abstract
Here we provide a step-by-step protocol for targeted single-cell RNA-seq and targeted Perturb-seq, as reported in the linked publication Schraivogel et al. Nat Meth 2020. The protocol describes cell preparation using flow cytometry, single-cell droplet formation with 10X Genomics, and targeted 3’ single-cell RNA-seq library preparation for Illumina sequencing.
Point-of-care serological assays for SARS-CoV-2 in a UK hospital population: potential for enhanced case finding
Authors: Pallett Scott , Patel Aatish , Davies Gary , Moore Luke 
Published: June 2020

Abstract
Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic, causing over 3,600,000 reported cases and 250,000 deaths worldwide.1 Case identification has predominantly been made by real-time polymerase chain reaction (PCR) during the acute phase and largely restricted to healthcare laboratories. Serological assays are emerging but independent validation is urgently required to assess their utility. Where a plurality of point-of-care (POC) SARS-CoV-2 antibody test kits have become available, we will therefore aim to evaluate a range of kits against the current available gold-standard diagnostic test of PCR in an initial, exploratory study. We will then proceed to carry out testing with 200 hospital inpatients using the OrientGene COVID-19 IgG/IgM Rapid Test Cassette against PCR in order to undergo a preliminary evaluation of POC serological test performance characteristics within a hospital inpatient cohort.
Role of school as a supportive entity for positive oral health behavior among adolescents in Ibadan, south-western Nigeria
Authors: Lawal Folake Barakat , Oke Gbemisola Aderemi 
Published: June 2020

Abstract
Background

The school is primed as an avenue for promoting health among adolescents. Conversely, the high unmet dental needs among school-going adolescents raises concern about the role of schools in this task. This study therefore assessed the role of schools in supporting positive oral health behavior of adolescents in a major city in a Low-Income-Country.
Methods

From 30 secondary schools that were randomly selected, 2097 students aged 12–18 years were recruited for this cross sectional study conducted in Ibadan, Nigeria. Data was obtained through the use of self-administered questionnaire to the students; this assessed oral health education and other oral health promotional activities that had taken place in the school from the students as well as their motivation to participate in school oral health programme. A checklist was used to assess availability of oral health promotional materials in the schools and the schools’ tuck shops for sale of healthy food. Data were analyzed with SPSS.
Results

The only oral health promotional activity reported in the schools was oral health education conducted in 8 (26.7%) schools and only 331 (15.8%) students had been educated about their oral health. There were no oral health promotional materials in the schools. About half, 1161 (55.4%) students were motivated to participate in school oral health program. All the tuck shops had cariogenic foods and drinks for sale. Students from schools where oral health education had been conducted were better motivated to participate in school oral health program (OR = 1.6,95%CI = 1.2-2.0,p < 0.001) but disagreed with restriction of sales of cariogenic food in school’s stuck shops (OR = 2.2,95%CI = 1.6-3.0,p < 0.001).
Conclusion

The schools surveyed played very little or no role to support positive oral health behavior of adolescents. Students who had been exposed to oral health education in school were better motivated about their oral health.
‘She Taught Me’: Factors Consumers Find Important in Nurse Practitioner and Pharmacist Prescriber Services
Authors: Officer Tara , Cumming Jackie , McBride-Henry Karen 
Published: June 2020

Abstract
Background: Advanced practitioner services, such as those nurse practitioners and pharmacist prescribers provide, are an opportunity to improve health care delivery. In New Zealand, these practitioners remain underutilised, despite research suggesting they offer safe and effective care, and considerable international literature recording patient satisfaction with these roles. This study aimed to explore factors underlying consumer satisfaction with primary health care nurse practitioner and pharmacist prescriber services.Methods: As part of a larger realist evaluation, 21 consumers of advanced practitioner services participated in semi-structured interviews. These interviews were transcribed and coded against context-mechanism-outcome configurations tested and refined throughout the research.Results: Study findings emphasise the importance of consumer confidence in the provider as a mechanism for establishing advanced practitioner roles. Underlying this confidence is a recognition that these practitioners are more accessible, engage at the consumer’s ‘level’, and operate with passion.Conclusions: This research offers learnings to re-engineer service delivery within primary health care to make best use of the entire health care team by including consumers in the design and introduction of new roles.
Design and psychometric properties of the obstacles to postoperative pain management in dementia scale (OPPMDS): A mixed methods exploratory study
Authors: Didvar Farzaneh , Ghaffari Fatemeh , Shamsalinia Abbas 
Published: June 2020

Abstract
BackgroundThe severe and acute pain of surgical site after hip fracture surgery among the elderly patients with dementia can threaten the treatment consequences. Pharmacological and non-pharmacological methods are used to reduce the risk of similar problems. Nevertheless, pain management may face different obstacles due to different reasons. Identifying and clarifying the acute pain management obstacles among the elderlies with dementia by the use of instruments tailored to the cultural structure of each community can lead to providing effective interventions.ObjectivesThis study aims to design and psychometrically validate the OPPMDS from the nurses’ point of view.MethodsA sequential explanatory mixed methods design was used for this study. The item-generation phase was carried out through two main methods: The inductive method (15 face-to-face and semi-structured interviews with 15 nurses) and the deductive method (literature review). Item reduction was conducted integration of qualitative, literature reviews and scale evaluation. For scale evaluation, face, content and construct validity (Exploratory Factor Analysis (EFA); N = 330) and Confirmatory Factor Analysis (CFA) ;N = 120), convergent and divergent Validity and Reliability (Internal consistency and stability) were conducted.ResultsThe EFA showed that the OPPMDS has three factors elderly-related factors, healthcare providers-related factors and system-related factors, which explained 57.572% of the overall variance. The CFA results indicated that the three-factor model of OPPMDS was best fit for the data. The convergent and divergent validity results suggested that the CR and AVE values of each factor was higher than 0.7 and 0.5, respectively (AVE > CR). The internal consistency of the first factor was 0.891, of the second was 0.929 and of the third was 0.890. The cronbach’s alpha coefficient of the scale was found to be 0.956. In addition, the test-retest results demonstrated high rates of agreement between the first and the second test scores (p < 0.001).ConclusionThe results of this study indicate that OPPMDS can be applied as a valid and reliable scale for measuring the postoperative acute pain management among the older patients with dementia and hip fracture.
Analysis to the clinical characteristics and prognosis of MDA5 positive patients with dermatomyositis
Authors: Yang Yiying , Zuo Xiaoxia , Zhang Huali , Luo Hui , Liu Sijia 
Published: June 2020

Abstract
Background: To explore the relationship between anti-MDA5 antibody and clinical manifestations of dermatomyositis(DM) and to explain the correlation of prognosis as well. Methods: Retrospective analysis was performed at the Department of Rheumatology and Immunology in Xiangya Hospital, Central South University from April 2017 to February 2019. The clinical data were collected from 109 patients with DM, and then the patients were divided into anti-MDA5 antibody positive group and negative group according to the results of antibody detection, after which statistical analysis was carried out with SPSS 23.0 software.Results: Among the 109 DM patients, the ratio of male to female is 1:2.3, with 58 positive anti-MDA5 antibody and 51 negative anti-MDA5 antibody. There is no difference in gender and age between the two groups, and patients with positive anti-MDA5 have a shorter course. The incidence of clinical symptoms, including Gottron sign, skin ulcer, joint pain, joint swelling, nail erythema, dyspnea, and cough in patients with anti-MDA5-positive DM is significantly higher than those in the anti-MDA5-negative group. Anti-MDA5 antibodies are inversely associated with tumorigenesis. Patients with anti-MDA5-positive DM have less elevation of muscle enzymes and are prone to ILD and RPILD, while patients with anti-MDA5-positive DM have a high mortality rate and poor prognosis.Conclusion: Combined with RP-ILD, the prognosis of DM is poor. When patients have these clinical manifestations and positive MDA5, they must actively undergo lung imaging examination and be alert to RP-ILD.
The relationship between miR-219-5p Gene Polymorphisms and the prognosis of colorectal cancer
Authors: Yan Yang , Du Xiaohui , Xia Shaoyou , Li Songyan , Teng Da , Hu Shidong , Wang Yufeng , Li Rong 
Published: June 2020

Abstract
Background

Colorectal cancer (CRC) is one of the most common malignant tumors, its morbidity and mortality are increasing year by year, it is a serious threat to people's health. Some studies have reported that miR-219-5p acts as a tumor suppressor in some malignant tumors. So the purpose of this study was to investigate the prognostic value of miR-219-5p expression in CRC patients.
Methods

QRT-PCR was used to detect the expression levels of miR-219-5p in CRC tissues and corresponding normal tissues (P < 0.001). The prognostic value of miR-219-5p in CRC was analyzed by Kaplan-Meier and Cox regression analysis.
Results

The results indicated that the expression of miR-219-5p was significantly lower in CRC tissues, and its expression was closely correlated with tumor differentiation, TNM staging and lymph node metastasis (all P < 0.05). Moreover, Kaplan Meier survival analysis showed that the patients with low expression of miR-219-5p had worse overall survival rates (P < 0.05). Cox regression analysis further demonstrated that miR-219-5p expression was an independent prognostic factor for survival time in CRC patients (P = 0.018, HR = 2.026 and 95%CI: 1.127–3.643).
Conclusions

All the results suggest that miR-219-5p expression can be used as a potential prognostic biomarker for CRC patients.