bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monitoring the results of enamel demineralization treatment with the caries infiltration method (according to laser fluorescence value)
Authors: Krivtsova D. A. , Maslak E. E. 
Published: April 2020

Relevance. In the actual dentistry a special place takes opportune diagnosis of early stages of dental caries and effective non-surgical treatment. In the recent times new approaches, technologies and methods for diagnosing focal demineralization of tooth enamel have been developed, among which the laser fluorescence method is widely used. Purpose. To study the results of local enamel demineralization treatment with the caries infiltration method according to laser fluorescence value. Materials and methods. The method of caries infiltration was applied in 99 permanent teeth with local enamel demineralization in 15 children aged 10-16 years. Laser fluorescence method was used for enamel demineralization assessment before and immediately after the treatment, after 6, 12 and 18 months. Three study groups were formed according to laser fluorescence value before the treatment: the first one – values 14-20 (initial enamel demineralization), the second one – values 21-29 (deep enamel demineralization), the third one – values ≥ 30 (enamel and dentine demineralization). Proportions (%), mean-values and standard errors (M±m) were calculated, significance (p) of differences was assessed according to Students’ criteria (t) at p < 0.05. Results. During 18 months after caries infiltration caries cavities forming were not revealed. The mean-values of laser fluorescence were in the first group before the treatment 17.38 ± 0.27, after the treatment 5.00±0.82, after 18 months – 4.82 ± 0.79; in the second group 25.42 ± 0.38, 15.25 ± 0.78 and 13.96 ± 0.75, in the third group 33.08 ± 0.69, 22.54 ± 1.39 and 20.77 ± 1.44 respectively. The differences between the values before and after the treatment were significant statistically (p < 0,001) in all groups. After 18 months the laser fluorescence values corresponding to healthy enamel were revealed in 94.1% cases in the first group, in 50.0% cases in the second group, and in 7.7% cases in the third group.Conclusions. Local enamel demineralization treatment of permanent teeth in children with the caries infiltration method prevented caries cavity forming. Monitoring laser fluorescence values revealed that the results of the treatment with the caries infiltration method depended on the depth of dental hard tissue demineralization.
Use of the ozonation method in treating dentin caries in children’s permanent teeth
Authors: Shevchenko M. A. , Kiselnikova L. P. , Petrova O. I. 
Published: April 2020

Relevance. Permanent teeth carious involvement starts from their eruption in children aged 5-6 years. Hard tissues mineralization in permanent teeth lasts long. Nowadays, efficacy of combined applying calcium containing drugs and the ozonation method while treating permanent teeth caries in children with incompleted processes of dental hard tissues mineralization has not been revealed.Purpose. Increasing effectiveness of dentin caries treatment of children's permanent teeth with incompleted mineralization processes in dental hard tissues. Materials and methods. There were carried out clinical and laboratory examinations and treatment of 41 children (aged 6-14). They had dentin caries in permanent teeth with incompleted mineralization processes in hard tissues .In 2 groups studied carious cavities were treated mechanically and medically and afterwards the dentin density measurement was made by the method of fluorecent analysis using DIAGNOdent apparatus. The mineralization degree of clinically intact dentin having been determined, in Group 1 Dycal paste and a hermetic temporary filling of glass ionomer cement were placed onto the floor of carious cavities. In Group 2 carious cavities were treated mechanically and medically and then ozonized during 30 seconds with Kavo - HealOzone apparatus followed by application of Dycal paste onto the floor of carious cavities and temporary filling with glass ionomer cement. Three months later, the temporary filling material and Dycal paste were removed out of the children's teeth in both groups and measuring mineralization degree of the clinically intact dentin was made again. Results. Dentin mineralization increase in Group 1 showed 33,9% following delayed filling technique. In Group 2 the ozonation method promoted the increase by 54,9%.Conclusions. Carious cavitiies ozonation before applying calcium containing material favours higher mineralization degree (by 21%).
Periodontopathogens: a new view. Systematic review. Part 1
Authors: Slazhneva E. S. , Tikhomirova E. A. , Atrushkevich V. G. 
Published: April 2020

Relevance. The modern view of periodontitis as a dysbiotic disease that occurs as a result of changes in the microbial composition of the subgingival region is considered in a systematic review. Purpose. To study a new paradigm of development of generalized periodontitis. Materials and methods. Randomized controlled trials (RCTS) were selected for the study, including cluster RCTS, controlled (non-randomized) microbiological and clinical studies of the oral microbiome in adult patients with generalized periodontitis over the past 10 years. Results. The development of periodontal dysbiosis occurs over a period of time, which slowly turns the symbiotic association of the host and microbe into a pathogenic one. This review examines the current paradigm of periodontitis progression, which calls into question the traditional concept of a disease induced by several particular periodontal pathogens belonging to the red complex.Conclusions. As follows from modern literature periodontitis is to a certain extent caused by the transition from a harmonious symbiotic bacterial community to a dysbiotic one. Recent scientific studies have shown that not single microorganism is not able to cause disease but the microbial community as a whole leads to the development of pathology.
Assessment of peridontal vessels hemodynamics among patients with diabetes mellitus type 1
Authors: Orekhova L. Yu. , Musaeva R. S. , Loboda E. S. , Grinenko Е. V. , Gulyanov G. Yu. 
Published: April 2020

Relevance. Processes of disturbance of regional hemodynamics, tissue blood flow, insufficiency of transcapillary metabolism and antioxidant system caused by dysfunction of periodontal vascular endothelium among patients with diabetes type 1 directly lead to diabetic microangiopathy accompanied by decrease of level of microcirculation and perfusion of periodontal tissues among patients with absolute insulin insufficiency. The reduction of linear and volumetric blood flow rates in periodontal vessels among patients with type 1 diabetes compared to values obtained by ultrasonic dopplerography in healthy patients can be considered as distinctive features of the manifestation of this systemic disease on microcirculation of periodontal tissues.Purpose. To evaluate the hemodynamics of periodontal vessels among patients with diabetes mellitus type 1 and without diabetes before and after conservative periodontal therapy.Materials and methods. 40 patients at the age 20-30 years were surveyed: 20 patients with diabetes mellitus type 1 and 20 patients without diabetes. All subjects underwent dental examination. To study the state of microcirculation of periodontal tissues patients of both groups underwent high-frequency ultrasound Doppler “Minimax-doppler-k”. Further was conducted professional oral hygiene complex with training in rules of individual oral hygiene. Reexamination was scheduled after 4 weeks. Results. During the conduction have been registered average baseline of the linear (Vam) and volumetric (Qam) blood flow in periodontal vessels in patients with diabetes mellitus type 1 and without diabetes. Average linear (Vam) and volumetric (Qam) blood flow before the conduction of professional oral hygiene complex were considerably lower compared to patients without diabetes. This points reduction of microcirculation and perfusion of periodontal tissues in patients with diabetes mellitus type 1 and without diabetes. Reassessment of blood flow in periodontal tissues in 4 weeks after professional oral hygiene revealed an increase in rate of microcirculation in periodontal tissues among patients with diabetes mellitus type 1 and without diabetes. Conclusion. Our study confirms the theory of hemodynamic impairment and local hemostasis in patients with type 1 diabetes, which is reflected in the appearance of trophic disorders of an inflammatory-dystrophic nature and a decrease in hemodynamic parameters. After conservative periodontal therapy, we revealed positive changes in hemodynamics of periodontal vessels, which was recorded using ultrasound dopplerography. Our results will allow us to select the optimal algorithms for the timely diagnosis, prevention and treatment of dental diseases in patients with type 1 diabetes in future.
Clinical Response and Pattern of B cell Suppression with Single Low Dose Rituximab in Nephrology
Authors: George Jacob , Alex Sunu , Thomas E.T. Arun , Gracious Noble , Vineetha Nalanda S. , Kumar Sajeev 
Published: April 2020

Background
There is no consensus regarding dose and frequency of rituximab in nephrology with extrapolation of doses used in treating lymphoproliferative disorders. There are no guidelines on targeting initial and subsequent doses on the basis of CD19+ B cells.

Methods
Initially, 100 mg rituximab was given to 42 adults with steroid-dependent nephrotic syndrome (SDNS) and frequently relapsing nephrotic syndrome (FRNS), idiopathic membranous nephropathy (MN), and high-immunologic-risk kidney transplantation. Absolute and percentage levels of CD19 B cells and clinical status were assessed at baseline, days 30, 90, and 180, and at 1 year. Subsequent doses of rituximab were on the basis of CD19 B cell reconstitution and clinical response.

Results
CD19 B cell percentage decreased from 16.3 ± 7.6 to 0.3 ± 0.3 (P≤0.001), 1.9 ± 1.7 (P≤0.001), and 4.0 ± 4.5 (P=0.005) by 30, 90, and 180 days, respectively. Suppression of CD19 B cell count below 1% at days 30, 90, and 180 was seen in 40 of 42 (95.2%), 18 of 42 (42.9%), and 7 of 42 (16.7%) patients, respectively. Of 30 with SDNS and FRNS followed up for 1 year, 29 (96.7%) went into remission at day 30. Remission was sustained in 23 (76.6%) at day 180 and 21 (70%) at 1 year. There was a significant decrease (P<0.001) in the dose of steroids needed to maintain remission at 180 days after rituximab (0.27 ± 0.02 mg/kg to 0.02 ± 0.00 mg/kg). CD19 B cell percentage at 90 days correlated with relapse (P=0.001; odds ratio 1.42; 95% confidence interval, 1.25 to 2.57). Eighteen (60%) required an additional dose. Of five with MN, four achieved remission by 6 months, which was sustained in three by 1 year. Of the seven kidney transplant recipients, two had antibody-mediated rejections, although CD19 B cells were suppressed even at 1 year.

Conclusions
Low-dose rituximab induces sustained depletion of CD19 B cells for up to 90 days. Its role in preventing relapses in SDNS, FRNS, MN, and rejection needs further study.
SAKRAMEN BAPTIS SEBAGAI SAKRMEN KESELAMATAN DAN PERSEKUTUAN PARA MURID KRISTUS
Authors: Wilhelmus Ola Rongan 
Published: April 2020

Baptism is a sacrament instituted and used by God Himself through Christ to purify, sanctify and to save human being out of the power of evil spirit. Baptism celebration maintaining in a proper and faithful manner will be brought about the fullness grace and favor of God to the Catholic faithful. The experiences of the Catholic faithful regarding God’s grace and favor should not be only responded by full faith but also be properly responded by full action to bring it to the entire nations and human races. The Catholic Church as a communion of Christ disciples has been sent and guided by the Holy Spirit to spread out such grace and favor of God to all nations. Pastoral assembly of Surabaya Diocese conducted in 2019 strongly articulated that Baptism is a mean exactly used by God Himself to channel His grace and salvation to the entire human beings. Hence, the Disciples of Christ have to fully respond it by full faith and opened hart. Christ Himself has sent His disciples to collectively spread out the grace, favor and salvation of God to all over the world. This good news has to be brought firstly to the inner circle of the Catholic families, neighbours, communities, parishes, and diocese then to the society in general.
Estimation of PM10 concentrations in Turkey based on Bayesian maximum entropy
Authors: BAYDAROĞLU YEŞİLKÖY Özlem 
Published: April 2020

Spatial and temporal distribution of PM10 is modeled by Bayesian Maximum Entropy (BME) method. It is the spatiotemporal estimation method which combines exact measurements with the secondary information by considering local uncertainties. In this study, daily average PM10 data are used to generate spatial and temporal PM10 maps. Both annual and seasonal estimations have been realized. This is the first study which concentrates on spatiotemporal distribution of PM10 for all regions of Turkey by using Bayesian Maximum Entropy method. Error variances are used as performance criteria in both seasonal and annual predictions. All prediction results stay within the limits of the confidence intervals. In addition, unknown PM10 values are estimated, including PM10 values over the seas. It is thought that the PM10 maps which show all regions of Turkey in detail are quite invaluable and informative.
MICROWAVE-ASSISTED EXTRACTION OF INULIN FROM JERUSALEM ARTICHOKE AND PARTIAL ACID HYDROLYSES
Authors: & Abood Alabadi 
Published: April 2020

The Recent study aimed to identify the optimum conditions for inulin extraction from jerusalem artichoke tuber (JAT) powder using microwave assisted extraction method, and partially hydrolysis of purified inulin for producing fructooligosaccharide (FOS) using citric acid & microwave energy. The extraction conducted at different temperature (90 – 95) C˚ at (700 W/5min, 450w/8 min and 350w/14 min). The extracted inulin was concentrated to (50 – 60) % of original volume using rotary evaporator, and purified by lime method. The purified inulin extract was concentrated to 32 brix and mixed with acetone (3:1 acetone : extract), kept for 24 h at 4 C˚, then centrifuged at 10000g / 15 min., the precipitate dried at 55 ˚C. Acid hydrolysis of purified inulin carried out at different pH values (1.5, 2.5 & 3.0) at (90 ±2) ˚C. Aliquot of inulin hydrolysate were taken after (5, 10, 15, 20, 25 & 30) min. and subjected to qualitative analysis by RP-HPLC and TLC. The obtained results indicated that the microwave assisted extraction at 700 W/ 5 min. / 95 ˚C was superior as compared to the rest. The yield of extracted inulin was about 39.61 % and the extraction efficiency was 94.31 %, while the optimum condition for inulin acid hydrolysis appeared to be at 90 ˚C/ 15 min at pH 2.5 and 450 W. The qualitative analysis using (RP-HPLC & TLC) showed that the DP of inulin units ranged from (2 - 35) and for FOS ranged from (2 – 9) unit.
EPIDEMIOLOGY OF SEASONAL INFLUENZA OUTBREAK AMONG IRAQI POPULATION:2018
Authors: & et al. Aufi 
Published: April 2020

This study aimed to highlight the prevalence of the seasonal influenza in the different Iraqi provinces during 2018 year to study the epidemiological aspects, and their effect on the frequency of disease and death cases caused by influenza virus. A total of 1359 throat and nasal swabs was collected from individuals suffering from influenza like illness (ILI) or severe acute respiratory infection (SARI) for testing influenza virus type A (H1N1 and H3N2) and type B. RNA extracted and amplification with specific primers and probes. Results showed the incidence rate of flu A 16.7 (227/1359) and 4.7 of flu B per 100000 people-year that included 14.9 for H1N1, 1.5 for H3N2 and the remaining value for mixed infection of H1N1 and H3N2. Regarding, the mortality rate 1.6 (21/227) with influenza A and 0.15 (2/64) with influenza B infections per 100000 person-year. The prevalence of flu A between the months showed significant differences, especially in the first two months of the year. The distribution of influenza infections in Baghdad province, which appeared the highest peak, then followed by Babyl, Waist and Salahaddin provinces. In conclusion, more surveillance studies are needed each year to provide database more important for WHO Eastern Mediterranean region (EMR) of influenza surveillance.
DETECTIN OF VASPIN RS2236242 AND CHEMERIN RS17173608 GENE POLYMORPHSIMS IN A SAMPLE OF OBESE IRAQI POLYCYCTIC OVARY SYNDROME WOMEN
Authors: & et al. Jasim 
Published: April 2020

This study was performed to detect assess Vaspin rs2236242 and Chemerin rs17173608 gene polymorphisms with its association with susceptibility of obese PCOS in Iraqi women .Blood samples from 100 women with obese PCOS and 75 healthy control women matched in age and BMI were collected from AL-Yarmouk Teaching hospital during February2018-July 2018 were enrolled in case control study. Tetra amplification refractory mutation system‐polymerase chain reaction (T-ARMS-PCR) was performed to detect the adipokine SNPs in patients and healthy women under study. Results demonstrated a significant variations in either genotype distribution and alleles frequencies between the obese PCOS and healthy women regarding vaspin rs2236242 polymorphism. The T allele increased the PCOS risk in comparison with the A allele which was the protective against PCOS, as well clear positive correlation between rs17173608 SNP of chemerin and susceptibility of PCOS was identified also, and The T allele had related with elevated PCOS risk as in comparison to the G allele. Data from this work determined for the first time a significant association between vaspin and chemerin SNPs and susceptibility PCOS risk in Iraqi obese women especially T allele .To confirm our findings new studies with large sample size and different ethnicities must be required.
Interferensi Sintaksis Bahasa Ibu terhadap Keterampilan Berbicara Bahasa Arab (Studi Kasus Mahasiswa Pendidikan Bahasa Arab STAI Syaichona Moh. Cholil Bangkalan)
Authors: Maisaroh Siti 
Published: April 2020

Arabic is the second language that has to be learned in formal education institution and also becomes compulsory subject for students of Arabic department. Each language has different elements that make the students are difficult to master foreign language (Arabic). Moreover, language mastery must have four language skills where composition is one of skills in language. This article explains the result of the research concerns with the Indonesian language syntactical interference on Arabic speaking. Based on the result of the research, the ability of speaking or Arabic conversation still influenced by Indonesian language, even thought many students are able to speak with the appropriate grammar (nahwu and shorof) especially for the students of Arabic Department of Syaichona Moh. Cholil State Institute of Islamic Studies Bangkalan.
Clima laboral y satisfacción del profesional de enfermería en el servicio de emergencias de un hospital público de Chiclayo, Perú.
Authors: Oblitas-Guerrero Susan Miriam 
Published: April 2020

Objetivo. Determinar la relación del clima laboral y la satisfacción del profesional de enfermería en el servicio de emergencias del Hospital Regional Lambayeque (HRL). Chiclayo, Perú, 2018. Material y métodos. Estudio transversal en 42 profesionales del servicio de emergencia del HRL. Para la recolección de datos se aplicó un cuestionario de clima laboral y otro de satisfacción laboral según Herzberg, adaptado por la investigadora. Resultados. La población se caracterizó por ser de sexo femenino (92,9 %), edad entre los 20 a 35 años, casadas (42,9 %), grado de maestro (21,4 %) y con especialidad en emergencia y desastres (92,9 %). Respecto al clima laboral, un 66,7 % lo percibe promedio, el 21,4 % saludable y el 11,9 % restante lo percibe no favorable. Respecto a la satisfacción laboral, un 66,7 % presenta un grado moderado de satisfacción, el 28,6 % un grado alto y el 4,8 % restante un grado bajo. Se observó relación entre el clima y satisfacción laboral (p=0,002). Conclusiones. Existe relación significativa del clima laboral y la satisfacción de los profesionales de enfermería del HRL en el periodo de estudio, por lo que es importante fortalecer las condiciones de trabajo de estos profesionales de la salud.
<b>Naturalcultural Hybridity and Becoming: Andrus Kivirähk’s <i>The Man Who Spoke Snakish</i> in a Material Ecocritical Perspective</b> // Hibridismo naturocultural y transformación: <i>The Man Who Spoke Snakish</i> desde la ecocrítica material
Authors: Sõrmus Maris 
Published: April 2020

The article takes a material ecocritical view on contemporary Estonian literature—Andrus Kivirähk’s The Man Who Spoke Snakish. The canonical novel, which focuses on the forest life being replaced with village life as well as the extinction of snakish, or, snake language, has importantly been classified as “the first Estonian eco-novel” (Hasselblatt 1262). In this light, I discuss the ways that nature emerges in new materialist terms as a subject, tangled with culture, challenging normative understandings of humanity. Particularly interesting is the fluid border of nature and culture, which suggests their reciprocal becoming. First, naturalcultural hybridity becomes manifest in the blurring of voices. Snakes emerge as the ancient brothers of humans, speaking with the last forest dwellers, while the protagonist speaks snakish and resembles a snake. The hybridity is further represented through the grandfather, human apes, and the protagonist’s sister. Above all, a hybrid “natureculture” is portrayed through Meeme, who resembles human “turf” and dissolves in nature, foregrounding the trans-corporeal naturalcultural entanglement. As Meeme becomes the earth, the novel suggests the intra-active becoming of the natural and the cultural, confirming the new materialist idea that there is no solid ground on which to stand but a dynamic world, where nature and culture finally still retreat into their own worlds. Resumen Este artículo analiza la obra The Man Who Spoke Snakish de Andrus Kivirähk, escritor estonio contemporáneo, desde una perspectiva ecocrítica materialista. Esta novela de culto, que se centra en la desaparición de la vida en el bosque y en la extinción del idioma de las serpientes, ha sido llamada “la primera econovela estonia” (Hasselblatt 1262). Teniendo esto en cuenta, observo cómo aparece la naturaleza como un sujeto entrelazado con la cultura, desafiando de esta manera el concepto normativo de ser humano. Es particularmente interesante el borroso límite entre naturaleza y cultura, haciendo hincapié en su transformación recíproca. En primer lugar, se manifiesta el hibridismo naturocultural en la mezcla de las voces. Las serpientes, hermanos de los humanos, hablan con los últimos habitantes del bosque, mientras que el protagonista habla el idioma de las serpientes y se parece a una serpiente. El mismo hibridismo es también evidente en la figura del abuelo, los simios y la hermana del protagonista. No obstante, la máxima declaración del hibridismo naturocultural es Meeme, que se parece a un pasto humano disolviéndose en la naturaleza y destacando el entrelazamiento transcorporal y naturocultural. Así como Meeme se convierte en tierra, la novela enfatiza la interacción del bosque y el pueblo reflejando una nueva comprensión materialista según la cual la naturaleza y la cultura se funden para formar un solo concepto.