bluuebunny/crossref_metadata_2025_split huggingface dataset:
Terra Indígena Xukuru-Kariri: avanços e recuos
Authors: Viegas Maria Ester Ferreira da Silva 
Published: October 2019

RESUMO: Neste artigo tentaremos abordar como os atores sociais (no caso os Xukuru-Kariri) de Palmeira dos Índios/AL ficaram excluídos do chamado “grande pacto político das elites brasileiras” e como se organizam enquanto grupo para assim fazerem frente aos senhores de terra que, tendo o Estado como garantidor de seu poder econômico, impedem que o campesinato seja ele indígena ou não, perturbe os esquemas da lógica férrea do economicismo desenvolvimentista. A discussão sobre o esfacelamento das terras indígenas no Brasil está no centro das preocupações daqueles que estudam sobre a questão agrária. O debate mais atual demonstra a intensidade e a centralidade da questão agrária no pensamento social e político no Brasil. É certo também que esta discussão reflete muito da conjuntura histórica e econômica do momento em que se contextualiza o discurso e também como se analisam os atores sociais envolvidos dentro do processo agrário brasileiro. O texto ora apresentado discute um momento de construção da emergência de mais uma aldeia do povo Xukuru-Kariri a partir de um movimento de (re) ocupação de terras, liderados então pelo índio Chiquinho Xukuru (índio desaldeado que até então vivia nas periferias da cidade de Palmeira dos Índios) desencadeia um processo de reforço e reformulação de sua identidade étnica, tendo em vista a ampliação de seu espaço político.
PALAVRAS-CHAVES: terra indígena, territorio, demarcação, xukuru-kariri
A utilização do método Pilates no tratamento de escoliose idiopática com pequenos graus de curvatura: uma revisão literária
Authors: Vasconcelos Fabricia Shirley de Oliveira Rodrigues 
Published: October 2019

O Método Pilates que foi idealizado pelo alemão Joseph Hubertus Pilates (1880-1967) durante a Primeira Guerra Mundial, inicialmente denominado “Contrologia”, base-se em princípios relacionados às noções de concentração, equilíbrio, percepção, controle corporal, flexibilidade, força e tônus muscular; utilizado hoje para ajudar a amezinhar Escoliose Idiopática. O objetivo deste trabalho é analisar, através de revisões de artigos, se o Método Pilates pode ajudar a amezinhar escolioses idiopáticas com pequenos graus de curvaturas. As pesquisas de caráter de revisões bibliográficas, e estudos de casos e consultas de materiais já publicados por autores que estudaram temas direcionados. Embora seja evidente a realização de novas pesquisas na área e, com maior quantidade de amostras, o Método Pilates é uma ferramenta comprovadamente útil na reabilitação, melhora na função e na dor causada pela escoliose.
Palavras-chave: Coluna Vertebral; Escoliose; Exercícios Físicos; Método Pilates.
ASSOCIAÇÃO ENTRE MAUS-TRATOS NA INFÂNCIA E DECLÍNIO COGNITIVO NO IDOSO: UMA REVISÃO INTEGRATIVA
Authors: Pascoal Jr Francisco , Nogueira Guilherme Marcos , Guidolin Bruno Luiz , Cataldo Neto Alfredo 
Published: October 2019

A violência contra a criança representa um importante problema de saúde pública, assim como o declínio cognitivo. A ligação entre essas variáveis vem sendo analisada cada vez mais, porque o estresse experimentado nos primeiros anos de vida pode estar relacionado a mudanças estruturais, funcionais e epigenéticas nas regiões cerebrais envolvidas na cognição. O objetivo deste estudo foi analisar essa associação, por meio de uma revisão integrativa da literatura, pelo meio da pesquisa bibliográfica das seguintes bases de dados: SciELO, LILACS, PUBMED e PsycINFO. O período de seleção dos artigos compreendeu os últimos cinco anos. No total, foram 33 artigos, dos quais dez eram artigos originais que focaram na relação entre maus-tratos na infância e declínio cognitivo em idosos. A presença de maus-tratos na infância possui associação com o declínio da função cognitiva no idoso, agravando-o sobremaneira e inclusive podendo colocar os indivíduos em risco de declínio cognitivo acentuado. Uma das limitações deste estudo foi a percepção de que a temática ainda carece de mais e melhores estudos que abordem esta relação na prática, por meio de estudos longitudinais.
Evaluation of losartan plus hydrochlorothiazide combination therapy against amlodipine monotherapy in patients of hypertension
Authors: Sawant Swati D. , Chawre Sanjeevani M. , Dudhal Kalpana S. , Bansode Amit A. 
Published: October 2019

Background: Microalbuminuria has been shown to predict cardiovascular disease (CVD) in patients with hypertension. Recently the FDC of losartan and hydrochlorothiazide (HCTZ) has been reported to be effective for achieving a target BP level and also improvement in cardiovascular prognosis. The present study was conducted to compare effect of losartan plus hydrochlorothiazide combination therapy and high dose amlodipine monotherapy on blood pressure and microalbuminuria.Methods: Total 184 patients with hypertension were randomly allocated to two groups. The patients in group 1 received Amlodipine 5 mg orally for first 4 weeks. The patients from group 2 received losartan 50 mg orally for first 4 weeks. Patients in group 1 were titrated to amlodipine 10 mg orally for next 4 weeks. The patients in group 2 were titrated to FDC of losartan (50 mg) plus HCTZ (12.5 mg) for next 4 weeks. Follow–up visits were scheduled at 4 weeks and 8 weeks. Pulse rate, sSBP and sDBP were estimated at each follow–up. Microalbuminuria was estimated at 8 weeks.Results: There was no significant difference in mean change in sSBP, sDBP and pulse rate between two treatment groups (p>0.05). There was greater reduction in microalbuminuria in group 2 patients (p<0.0001). The adverse effects such as flushing and lower extremity oedema were significantly more in amlodipine group (p<0.05).Conclusions: Losartan plus HCTZ has similar effect on BP, better safety profile and superior effect on microalbuminuria level reduction.
Analysis of success of vaginal birth after cesarean in relation to indication of primary caesarean section: a tertiary care experience
Authors: Gupta Neha , De Arpita , Gupta Nidhi 
Published: October 2019

Background: Apprehensions related to vaginal birth after caesarean (VBAC) has reduced rates of successful vaginal trials over last decade. The objective of this study was to identify the indications of first caesarean section that can lead to a successful trial of labour in subsequent pregnancy.Methods: Retrospective cohort study was done between November 2014 and October 2017. Data from the case records was analysed.Results: Study over 3 years from 2014 to 2017 revealed fetal distress (82.7%), breech (72.2%), transverse lie (66.7%), antepartum haemorrhage (56.2%) and twins with first non-cephalic (57.9%) have successful outcome of VBAC whereas obstructed labour (19.2%) and failed induction (18.4%) in previous pregnancy have poor outcome for VBAC.Conclusions: Attempts to allow trial of labour after one previous caesarean section with fetal distress, malpresentation and twins as indications of caesarean in previous pregnancy are safe and should be encouraged.
Study of blood groups and throat swab culture in chronic tonsillitis among pediatric age group
Authors: M. S. Sudhakar Rao , P. Apoorva , K. Keerthi 
Published: October 2019

<p class="abstract"><strong>Background:</strong> Chronic tonsillitis is a disease of childhood with a peak incidence at 5-6 years of age and the commonest organism being Group A beta hemolytic streptococcus (GABHS). Accurate diagnosis of strep­tococcal infection is essential to limit transmission, reduce the complications and period of communicability. To study the association between blood groups and culture findings of throat swab in chronic tonsillitis among pediatric age group is the aim of our study.</p><p class="abstract"><strong>Methods:</strong> 60 pediatric patients of clinically diagnosed chronic tonsillitis of both genders who attended outpatient department of otorhinolaryngology and head and neck surgery VIMS, Ballari, Karnataka, India were included in this study on simple random basis. Throat swabs obtained from them were subjected for culture test along with blood grouping and Rh typing. </p><p class="abstract"><strong>Results:</strong> In our study, among 60 patients, who presented with recurrent episodes of throat pain for duration of &lt;1 year were 31 (51.7%), of 1-3 years were 15 (25%) and of &gt;3 years were 14 (23.3%). 42 patients (70%) had grade 3 tonsillar enlargement, 14 (23.3%) had grade 2 and 4 (6.7%) had grade 4 tonsillar enlargement. 22 were of B positive blood group (36.7%), 19 of O positive (31.7%), 12 of A positive (20%) and 7 patients of AB positive blood group (11.7%).</p><p><strong>Conclusions:</strong> Statistically significant association is found among school going age group of both genders infected by the <em>Streptococcal</em> species (p&lt;0.05). Patients of O positive blood group were infected more followed by B positive blood group. </p>
The Authority of Honorary Committee of Notary in Obtaining the Copy of Original Deed Owned by Yasmine Citra Maulania
Authors: Maulania Yasmine Citra , Husin Sukanda , Benni Beatrix 
Published: October 2019

Honorary Committee of Notary is an institution chosen by the Minister of Justice and Human Rights as the supervisor of Notary position working based on Law Number 2 of 2016 regarding Amendment on Law Number 30 of 2004 regarding Notary Position. In Article 66 of Law of Notary Position, Honorary Committee of Notary basically has authority to give approval on the request of original deed copy. The implementation of this authority is set in the Regulation of Justice and Human Rights Minister Number 7 of 2016 regarding Honorary Committee of Notary. The validity of this Honorary Committee of Notary automatically gets rejection from some parties if related to judicature. Therefore, the researcher makes research question on how the role of Honorary Committee of Notary in obtaining original deed copy and how the effect of Honorary Committee of Notary consideration towards obtaining copy of original deed. The research method used is judicial normative in which it is an approach done based on primary law material by reviewing theories, concepts, law principles, and regulations regarding to this research. When the copy obtaining is requested to the Honorary Committee of Notary, the members of committee will conduct a meeting. In the meeting, the Public Notary must show his original deed and the members of Honorary Committee of Notary will assess whether it has been in line with the notary protocol or not. If it has been in line with it, the Honorary Committee of Notary deserves to refuse the proposal. This refusal will not be an issue in the assembly because the judicature can run by being supported by other proofs.
TURKEY-VATICAN RELATIONS FROM THE OTTOMANS TO THE REPUBLIC
Authors: TÜRKAN Ahmet 
Published: October 2019

The relations between Turkey and Vatican had started to be spoken more frequentlyafter Pope Francis’s visit to Turkey in 2014. Turkey-Vatican relations which were established formally in 1960 embody an important historical past. Formal relations, which were tried to be established substantially during the reign of Sultan Abdulhamit II,-especially to reduce the impact of France over the Catholics and for many other reasons-, were not established due to many different reasons, each different than the other.In this study, we will try to examine the reasons why the Turkish-Vatican relations that started at high friendship level in the second half of the 19th century, hadn’t been realized at formal level until the second half of the 20th century. Furthermore, we will examine the effective factors over these relations both for the Ottoman and the Republic periods. We will also discuss to what degree the Catholics and the Orthodox in Turkey were influential over these relations. In this sense, main part of our work will be within the frame of first-hand sources and documents obtained from the Turkish Republic State Archives.
PERENCANAAN KOMUNIKASI PEMASARAN TERPADU ASIAN GAMES 2018 SEBAGAI NATION BRANDING
Authors: Wardani Ayu Septiana , Dyanasari Reni 
Published: October 2019

In addition to acting as a government system, the Indonesian state also acts as a brand that makes it necessary to make efforts to nation branding. Sport mega event is one way to build nation branding. Indonesia was trusted to host the Asian Games 2018. By being in charge of holding a sport mega event (SMEs), Indonesia will gain some benefits from global publicity that can be used to build nation branding. Indonesia's success in holding the Asian Games 2018 has made a positive impact on Indonesia's nation branding. In the implementation of SMES, integrated marketing communications is one of the important factors that determine its success. Indonesia's success in using the Asian Games 2018 moment to build nation branding attracted the attention of researcher to conduct research on the Asian Games 2018 integrated marketing communications planning as a means of building nation branding using qualitative methods. The results of this study indicate that Indonesia implemented six steps in zero based integrated marketing communications planning. When conducting a promotion based on this plan, INASGOC also applies two steps in building Indonesia’s nation branding and communicating the values that Indonesia have through three components in the Nation Brand Hexagon.Keywords: Asian Games, INASGOC, Promotion, Nation Branding, Indonesia
Osteochondral Autograft Transplant (Mosaicplasty) for Knee Articular Cartilage Defects
Authors: Inderhaug Eivind , Solheim Eirik 
Published: October 2019

Osteochondral autograft transplant (mosaicplasty) is a cartilage repair procedure for patients with knee articular cartilage lesions of a substantial size (>3 cm2). Patient selection is key to a successful result; patients with established osteoarthritis or systematic disorders such as rheumatoid arthritis should not undergo surgery. An exercise program involving neuromuscular training for a minimum of 3 months should be attempted before proceeding to osteochondral autograft transplant. The procedure can, in many cases, be performed arthroscopically. Patients should, however, provide consent for a mini-arthrotomy as this might be needed to achieve optimal access for graft harvesting and insertion. The procedure, in general, consists of 4 major steps. (1) At the initial arthroscopic examination, the size and localization of the defect are assessed after a proper debridement has been performed. The number and size of autografts needed can thereafter be assessed. (2) Graft harvesting is then performed from the periphery of the non-weight-bearing trochlea. (3) To prepare for graft insertion at the recipient site, a drill guide is inserted perpendicular to the joint surface in the defect to allow graft sockets to be reamed. (4) Grafts should be spaced approximately 3 mm apart to avoid confluence of tunnels and weakening of condyles. The orientation and depth of insertion of the grafts are key to mimic the native curvature of the affected joint surface.
After an initial phase of non-weight-bearing focusing on range of motion, a gradual increase in neuromuscular exercises is recommended. Patients are typically advised to delay their return to sports until 6 months at the earliest. Results after mosaicplasty have shown that the procedure improves subjective outcomes, compared with baseline function, for up to 10 years after surgery. The additional effect over traditional microfracture treatment is, however, reduced over time. A study evaluating early factors affecting outcomes after cartilage repair procedures (including mosaicplasty) found that a series of factors, such as the time from the onset of symptoms to surgery, number and size of lesions, location and quality of surrounding cartilage, as well as concomitant meniscal injuries, were important
3
.
Cyclic compression emerged dual effects on the osteogenic and osteoclastic status of LPS-induced inflammatory human periodontal ligament cells according to loading force
Authors: Jia Ru , Yi Yingjie , Liu Jie , Pei Dandan , Hu Bo , Hao Huanmeng , Wu Linyue , Wang Zhenzhen , Luo Xiao , Lu Yi 
Published: October 2019

Abstract
Background: Appropriate mechanical stimulation is essential for bone homeostasis in healthy periodontal tissues. While the osteogenesis and osteoclast differentiation of inflammatory periodontal ligament cells under different dynamic loading has not been yet clear. The aim of this study is to clarify the inflammatory, osteogenic and pro-osteoclastic effects of different cyclic stress loading on the inflammatory human periodontal ligament cells (hPDLCs) .
Methods: hPDLCs were isolated from healthy premolars and cultured in alpha minimum Eagle’s medium (α-MEM). Lipopolysaccharides (LPS) were used to induce the inflammation state of hPDLCs in vitro . Determination of LPS concentration for the model of inflammatory periodontium was based on MTT and genes expression analysis. Then the cyclic stress of 0, 0-50, 0-90 and 0-150 kPa was applied to the inflammatory hPDLCs for 5 days respectively. mRNA and protein levels of osteogenic, osteoclastic and inflammation-related markers were examined after the treatment.
Results: MTT and RT-PCR results showed that 10 μg/ml LPS up-regulated TNF-α, IL-1β, IL-6, IL-8 and MCP-1 mRNA levels ( P <0.05) and did not affect the cell viability ( P >0.05). The excessive loading of stress (150 kPa) with or without LPS strongly increased the expression of inflammatory-related markers TNF-α , IL-1β , IL-6 , IL-8 , MCP-1 ( P <0.05) and osteoclastic markers RANKL , M-CSF , PTHLH and CTSK compared with other groups ( P <0.05), but had no significant effect on osteogenic genes. While 0-90 kPa cyclic pressure could up-regulate the expression of osteogenic genes ALP, COL-1 , RUNX2, OCN, OPN and OSX in the healthy hPDLSCs.
Conclusions: Collectively, it could be concluded that 0-150 kPa was an excessive stress loading which accelerated both inflammatory and osteoclastic effects, while 0-90 kPa may be a positive factor for the osteogenic differentiation of hPDLCs in vitro.
Electronic Health Record Nested Pragmatic Randomized Controlled Trial of a Reminder System for Serum Lithium Level Monitoring in Patients with Mood Disorder: KONOTORI study protocol
Authors: Seki Tomotsugu , Aki Morio , Kawashima Hirotsugu , Miki Tomotaka , Tanaka Shiro , Kawakami Koji , Furukawa Toshi A. 
Published: October 2019

Abstract
Background: The weaknesses of classical explanatory randomized controlled trials (RCTs) include limited generalizability, high cost, and time burden. Pragmatic RCTs nested within electronic health records (EHRs) can be useful to overcome such limitations. Serum lithium level monitoring has often been underutilized in real-world practice in Japan. This trial aims to evaluate the effectiveness of the EHR-nested reminder system for serum lithium level monitoring in the maintenance of therapeutic lithium concentration and in the improvement of the quality of care for patients on lithium maintenance therapy. Methods: The Kyoto tOyooka Nested cOntrolled Trial Of Reminders (KONOTORI trial) is an EHR-nested, parallel-group, stratified permuted block randomized controlled trial. Screening, random allocation, reminder output, and outcome collection will be conducted automatically by the EHR-nested trial program. Patients with a mood disorder taking lithium carbonate for maintenance therapy will be randomly allocated to the two-step reminder system for serum lithium level monitoring or to usual care. The primary outcome is achievement of therapeutic serum lithium concentration between 0.4 and 1.0 mEq/L after 18 months. Discussion: The KONOTORI trial uses EHRs to enable the efficient conduct of a pragmatic trial of the reminder system for lithium monitoring. This may contribute to improved quality of care for patients on lithium maintenance therapy.
Chinese herbal medicine Tangshen Formula Treatment For Type 2 Diabetic Kidney Disease in Early Stage : study protocol for a randomized controlled trial
Authors: Jin De , Huang Wen-Jing , Meng Xiang , Yang Fan , Bao Qi , Zhang Mei-zhen , Yang Ya-nan , Lian Feng-Mei , Ni Qing , Tong Xiao-Lin 
Published: October 2019

Abstract
Abstract
Background:
Diabetic kidney disease (DKD) is the main cause of end stage kidney disease (ESKD) and It has become a heavy economic and social burden due to its high prevalence and morbidity. The most effective strategy is that patients with DKD should be diagnosed and treated early. Preliminary studies showed the Chinese herbal Tangshen Formula (TSF) may delay the progression of DKD, reducing micro-and macro-albuminuria and improving renal function. We designed a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of TSF in patients with DKD.

Methods/design:
This trial is a thirteen-center, randomized, double-blind, placebo-controlled study. 623 participants will be randomized in a 1:1 ratio to an experiment group (TSF plus Losartan) and a control group (placebo plus Losartan). The trial cycle will last 24 weeks. The primary outcome will be the change in Urine microalbumin creatinine ratio （ ACR ） from baseline to week 24. The secondary outcome will be the change in the rate of progression into the clinical proteinuria period after intervention, the rate of urine microalbumin negative conversion, the rate of normal urinary microalbumin, doubling rate of baseline creatinine value and glomerular filtration rate (GFR) between the two groups. Safety in medication will also be evaluated.

Discussion: We hypothesize that type 2 diabetic patients in early stage of DKD will benefit from TSF. If successful, this study will provide evidence-based recommendations for clinicians.

Trial registration: ClinicalTrials.gov (NCT03009864)

Keywords: Diabetes Kidney Disease, Traditional Chinese medicine, Treatment, Randomized controlled trial
Effect of a community-based intervention for cardiovascular risk factor control on stroke mortality in rural Gadchiroli, India: study protocol for a cluster randomised controlled trial
Authors: Kalkonde Yogeshwar , Deshmukh Mahesh , Nila Sindhu , Jadhao Sunil , Bang Abhay 
Published: October 2019

Abstract
Background
Stroke has emerged as a leading cause of death in rural India. However, well tested healthcare interventions to reduce stroke mortality in rural under-resourced settings are lacking. The aim of this study is to evaluate the effect of a community-based preventive intervention on stroke mortality in rural Gadchiroli, India.
Methods
The study is a two-arm, parallel group, cluster randomised controlled trial where 32 villages each will be randomised to the intervention and the enhanced usual care (EUC) arm. In the intervention arm, individuals ≥ 50 years of age will be screened for hypertension, diabetes and stroke by trained Community Health Workers (CHWs). Screen positive individuals will be referred to a mobile outreach clinic which will visit intervention villages. A physician in the clinic will confirm the diagnosis, provide guideline-based treatment and follow up patients at periodic intervals. The CHWs will make home visits once a month to ensure medication compliance and counsel patients to reduce salt consumption and quit tobacco and alcohol. In the EUC arm, households will be provided information on the ill effects of tobacco and steps to quit it. Individuals from both the arms will have access to government’s national programme for prevention and control of non-communicable diseases where treatment for hypertension, diabetes and preventive treatment after stroke is available, nearest at the primary health centres (PHCs). The intervention will be implemented for 3.5 years. The primary outcome will be reduction in stroke mortality in the last 2.5 years of the intervention.
Discussion
This trial will provide important information regarding the feasibility and effect of a community-based preventive intervention package on stroke mortality in a rural under-resourced setting and can inform India’s non-communicable diseases prevention and control programme. If successful, such an intervention can be scaled up in rural regions of India and other countries.