bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERSPECTIVES ON THE QUALITY OF LIFE OF PATIENTS WITH EPIDERMOLYSIS BULLOSA AND THE IMPACT ON THE PATIENT’S FAMILY
Authors: Mukusheva S.K. , Ospanova S.A. , Sukhanberdiyeva Z.M. 
Published: December 2024

Bullous epidermolysis is a rare, chronic condition affecting the skin and mucous membranes, characterized by blistering and erosions from minimal trauma. This debilitating disease significantly impacts the psychosocial well-being of patients and their families. The study explores the aspects of life most affected by bullous epidermolysis using a customized questionnaire based on DEBRA International guidelines and palliative care surveys. The research includes a comparative analysis of survey responses from individuals with bullous epidermolysis and those with other serious health conditions, supplemented by a literature review of related patient studies. Key findings identify crucial areas where families need more support, including emotional, social, and practical challenges. The study provides actionable recommendations to improve the quality of life for bullous epidermolysis patients and their families. These recommendations focus on fostering multidisciplinary care approaches, enhancing psychosocial engagement, and strengthening community support networks. The findings underline the importance of targeted interventions and suggest directions for future research to address unmet needs and optimize support systems for individuals living with bullous epidermolysis.
Эпидермолиз буллоза – теріге және шырышты қабықтарға әсер ететін сирек кездесетін созылмалы ауру. Бұл әлсірететін ауру пациенттердің және олардың отбасыларының психоәлеуметтік әл-ауқатына айтарлықтай әсер етеді. Зерттеу DEBRA халықаралық ұсынымдары мен паллиативтік көмек сауалнамасы негізінде әзірленген бейімделген сауалнаманы пайдалана отырып, эпидермолиз буллоза ең көп әсер ететін өмір аспектілерін зерттейді. Жұмыс эпидермолиз буллоза бар адамдар мен ауыр аурулары бар басқа пациенттердің жауаптарын салыстырмалы талдауды, сондай-ақ ұқсас зерттеулерге әдебиеттерді шолуды қамтиды. Негізгі қорытындылар отбасыларға эмоционалдық, әлеуметтік және практикалық аспектілерді қоса алғанда, көбірек қолдауды қажет ететін негізгі салаларды көрсетеді. Зерттеу мультидисциплинарлы көзқарасты, психоәлеуметтік қолдауды және қоғамдастықты қолдау желісін дамытуды баса көрсете отырып, эпидермолиз буллоза бар науқастардың және олардың отбасыларының өмір сапасын жақсарту бойынша нақты ұсыныстарды ұсынады. Нәтижелер мақсатты араласудың маңыздылығын көрсетеді және эпидермолиз буллоза бар адамдарға күтім жасау жүйелерін оңтайландыру үшін одан әрі зерттеу бағыттарын ұсынады.
The Outcomes Fistulectomy with Immediate Sphincter Repair for Treatment of High Trans-sphincteric Anal Fistula: Experience from a Low-Resource setting Hospital.
Authors: Elnaim Abdel Latif , Wong Michael , Sagap Ismail 
Published: December 2024

Background Managing high trans-sphincteric anal fistulas is challenging due to the need to prevent recurrence while preserving sphincter function. Fistulectomy combined with immediate sphincter repair may offer a balanced approach to achieving these objectives. Objectives This study evaluates the short-term outcomes of fistulectomy with sphincteroplasty in treating high trans-sphincteric anal fistulas. Methods We conducted a prospective observational study of patients undergoing fistulectomy with immediate sphincter repair for high trans-sphincteric anal fistula between June 2019 and May 2021. Demographic data, perioperative pain scores, hospital stay length, and Wexner incontinence scores were recorded for analysis. Results A total of 107 patients met the inclusion criteria, with 80 (74.3%) male participants and a median age of 40 years (range: 18–66). Among them, eight (7.4%) were on steroids, and twelve (11.2%) had diabetes mellitus. Seven (6.5%) had a history of anal conditions or surgeries. Post-operatively, one patient (0.9%) experienced minor bleeding that resolved spontaneously. Additional analgesia was required for six (5.6%) patients on the first post-operative day, and two patients developed surgical site infections that were managed with simple dressings. Most participants resumed normal activities within a week. Anal stenosis occurred in one (0.9%) patient and improved with a single anal dilatation session. Chronic anal pain was reported by four (3.7%) patients, gas incontinence by one (0.9%), and pruritus ani by four (3.7%). The majority of wounds healed within one month. Conclusions Fistulectomy with immediate sphincter repair is a safe and feasible option for treating high trans-sphincteric anal fistulas in Sudan, with an acceptable rate of complications and promising short-term outcomes.
Relationship between Psychological, Subjective and Social Well-Being of Victims of the Armed Conflict in the Municipality of Chalán-Sucre
Authors: Hernández Cindy Henrriquez , Mendivil Patricia Hernández , Morales María Alexandra Pinillos , Gómez Marelis Domínguez , Quiroz Luis Angel Herazo 
Published: December 2024

The objective of this research was to determine the relationship between psychological, subjective and social well-being in victims of the armed conflict in the municipality of Chalán, Sucre. A quantitative approach was used within the positivist paradigm, with a non-experimental design of transversal cohort and correlational scope. The sample consisted of 75 participants, aged between 19 and 80 years, to whom the scales of psychological well-being, subscale of subjective well-being and social well-being were applied. Data analysis included descriptive, frequency and Pearson correlation statistics. The results indicate that autonomy (18.51) is the dimension with the highest mean in psychological well-being, while for social well-being it was social acceptance (20.28). For its part, subjective well-being presents a mean of 74.53. Regarding the relationship, the results show very low correlation values between the three variables, suggesting that there is no significant relationship between them.
Avbildade tecken & avbildningar som tecken. Ikonologins och semiotikens delade skäl
Authors: Andersson Fred 
Published: December 2024

Title: Depicted Signs and Depictions as Signs – Common Reasons for Iconology and Semiotics
The aim of this article is to describe some common reasons and origins of modern Icono-logy and Semiotics, and to question the dichotomy which is sometimes made between these disciplines. When emblematics and iconology were established in the Sixteenth Century, first with Andreas Alciatus’ Emblemata and later with Cæsare Ripa’s Iconologia, poetic imagery and rhetorical figures were primary points of reference. Rather than separating visual and verbal capacities, these authors merely affirmed that both visible pictures and spoken or written words could communicate the same images. An antagonism between iconology and semiotics was hardly possible until modern linguistics separated the study of language systems from the study of symbolic systems. The denotation and the connotation, as defined in studies of language systems, have however been compared to Erwin Panofsky’s primary and secondary levels of subject matter, respectively. This study rather concludes that the place of denotation in iconological analysis would be the secondary or iconographic level. Differently put, the depiction of signs in iconography could structurally be compared to the depiction or visual denotation as sign. In this manner, common reasons for a systematic approach can be found both in the early beginnings and in recent developments of iconology and semiotics. The reasons may however be different than previously conceived.
PERANCANGAN USER INTERFACE (UI) MONITORING TUMBUH KEMBANG ANAK BERBASIS ANDROID DENGAN METODE CATWOE
Authors: Tri Rahayu Tri Rahayu , Bambang Triwahyono  , Anita Muliawati  , Sarika afrizal  , Widya Khafa Nofa  
Published: December 2024

Perkembangan teknologi merupakan salah satu faktor yang berpengaruh di bidang komputer dan informasi ,salah satunya membawa pengaruh terhadap komunikasi jarak jauh. kondisi saat ini pastinya sangat dibutuhkan sekali teknologi, dimana semua serba digital sehingga memudahkan orang untuk melakukan aktifitas dan tidak perlu harus datang kesuatu tempat dalam bentuk lokasi tertentu yang membutuhkan jarak dan waktu. Seiring pertumbuhan teknologi tersebut maka banyak juga kebutuhan terkait dengan kemudah dalam segi teknologi salah satunya dibidang kesehatan khususnya pada anak yang sangat rentang terhadap sumber penyakit. Dari sini kami mengangkat salah satu dari tema kesehatan bagi anak untuk mencegah adanya peningkatan penyakit pada anak. Pada monitoring tumbuh kembang anak terbagi menjadi dua, yaitu pertumbuhan dan perkembangan. Perlu adanya pantauan dari pertumbuhan dan perkembangan anak di samping itu, masih dirasakan kurangnya kesadaran sebagian anggota masyarakat akan perlunya pengembangan kesejahteraan terhadap anak. Kami merancang user interface Aplikasi Baby Care dengan metode catwoe, suatu inovasi yang beda dan praktis aplikasi ini dapat dikatakan juga sebagai monitoring untuk si bayi atau anak orangtua. Aplikasi ini memberikan informasi tentang pertumbuhan dan perkembangan untuk anak untuk kesejahteraan anak di masa pertumbuhannya.
Habitual tea consumption is associated with a lower prevalence of kidney stone disease in postmenopausal women
Authors: Wu Kuan-Hsien , Lee Jia-In , Lee Yung-Chin , Shen Jung-Tsung , Wang Hsun-Shuan , Tsao Yao-Hsuan , Wu Yi-Hsuan , Huang Shu-Pin , Chen Szu-Chia , Jhan Jhen-Hao , Geng Jiun-Hung 
Published: December 2024

Background
Menopause is associated with an increased risk of kidney stone disease (KSD). However, for postmenopausal women, how to avoid KSD has rarely been studied. The aim of this study was to explore whether drinking tea is associated with a reduction in the prevalence of KSD in postmenopausal women.

Methods
We collected 11,484 postmenopausal women from the Taiwan Biobank, and used questionnaires to obtain information on tea drinking, KSD, and comorbidities. The participants were divided into two groups according to habitual tea consumption: tea-drinking and non-tea-drinking groups. The association between habitual tea consumption and KSD was examined by logistic regression analysis.

Results
There were 2,035 postmenopausal women in the tea-drinking group and 9,449 postmenopausal women in the non-tea-drinking group. The mean age of all participants was 61 years. Compared to the non-tea-drinking group, the tea-drinking group had a significantly lower prevalence of KSD (7% vs. 5%). The odds ratio (OR) of KSD was lower in those who habitually drank tea than in those who did not (OR = 0.78; 95% confidence interval [CI] [0.63 to 0.96]) after adjusting for confounders. Moreover, postmenopausal women with a daily intake of two cups of tea or more had a 30% reduced risk of KSD compared to those who did not habitually drink tea (OR = 0.71, 95% CI [0.56 to 0.90]).

Conclusions
Our results suggest that habitual tea drinking may be associated with a reduction in the prevalence of KSD in postmenopausal women. Further studies are warranted to investigate the protective effect of tea on the development of KSD.
Assessment of occupational noise-related hearing impairment among dental health personnel
Authors: Al-Omoush Salah A , Abdul-Baqi Khader J , Zuriekat Margaret , Alsoleihat Firas , Elmanaseer Wijdan R , Jamani Kifah D 
Published: November 2019

Abstract

Objectives
The purpose of the study was to examine hearing thresholds among dental personnel. The secondary aim was to evaluate sound levels among dental equipment that dental personnel are exposed to.

Methods
Two hundred forty-four dentists, dental technicians, dental assistants, and dental students participated. Sixty-two participated as a control group. Audiological thresholds for the test groups were compared to the control group. All participants were from Jordan University Hospital. Participants completed a questionnaire in addition to their audiometric testing. Otoscopy, tympanometry, and pure tone audiometry were included in their assessment. Three-factor ANOVA and t tests were utilized to assess the statistical differences of hearing thresholds among the groups and between the two ears. Pearson correlation test was used to assess the effect of age, experience, and duration of exposure on the degree of hearing loss in the test groups for both ears.

Results
The authors reported statistically significant differences among hearing thresholds between the control group and others. Left hearing thresholds were noted to be significantly poorer in the left versus right ear at 1000, 2000, 4000, and 8000 Hz in dental assistants. The authors also reported a significant relationship between the degree of hearing impairment among dental assistants and the daily duration of exposure to dental occupational noise, followed by age.

Conclusion
Hearing impairment was higher among dental professionals than the control group and especially among dental assistants and technicians. The authors recommended screening guidelines and adapting hearing protection methods for dental professionals and particularly for dental assistants and technicians.
Factors Predictive of Radiographic Progression in Ankylosing Spondylitis
Authors: Sari Ismail , Lee Seunghun , Tomlinson George , Johnson Sindhu R. , Inman Robert D. , Haroon Nigil 
Published: November 2019

ObjectiveUsing a longitudinal observational cohort of ankylosing spondylitis (AS) patients, we sought to identify progression rates and factors predictive of spinal progression. As a secondary aim, we analyzed the effect of tumor necrosis factor inhibitor (TNFi) treatment on radiographic progression.MethodsAS patients who had baseline and follow‐up cervical and lumbar radiographs were included in the study. Radiographic damage was assessed by the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS). A change of 2 mSASSS units in 2 years was defined as progression. The characteristics of the study group such as demographic, clinical, laboratory, and treatment history were collected.ResultsThere were 350 patients in the study. The mean ± SD mSASSS increased from 9.3 ± 15.8 units at baseline to 17.7 ± 21.7 units by the sixth year. Mean ± SD changes in mSASSS between the years 0 to 2, 2 to 4, and 4 to 6 were 1.23 ± 2.68, 1.47 ± 2.86, and 1.52 ± 3.7 units, respectively. Overall, 24.3% of the group progressed over 2 years. Male sex (hazard ratio [HR] 2.46 [95% confidence interval (95% CI) 1.05, 5.76]), the presence of baseline damage (HR 7.98 [95% CI 3.98, 16]), increased inflammatory markers (log C‐reactive protein level HR 1.35 [95% CI 1.07, 1.70]), and TNFi use (HR 0.82 [95% CI 0.70, 0.96]) were predictive of radiographic progression. There was a 20% reduction in the rate of progression with TNFi.ConclusionMale sex, the presence of baseline damage, active disease state, and higher inflammatory markers confer a high risk for disease progression. Treatment with TNFi showed a disease‐modifying effect by slowing the rate of radiographic progression.
Worldcraft: Building Worlds One Project at a Time
Authors: Pahhota Daria 
Published: November 2019

AbstractOver the last decade, Copenhagen‐ and New York‐based architecture and urbanism firm Bjarke Ingels Group (BIG) has enjoyed a meteoric rise on the world stage. Daria Pahhota has presided over this as its Chief Communications Officer, heading the team that decides where, when and how the practice disseminates its news, messages and personality. Here she gives us a glimpse behind the scenes.
Exhibiting Architecture: Between the Profession and the Public
Authors: Hopkins Owen 
Published: November 2019

AbstractLondon's Sir John Soane's Museum Senior Curator, Owen Hopkins, recounts the modern‐day encumbrances and successes of communicating architecture to the public. This mission to attract the public's understanding and appreciation of architecture is crucial to giving people the ‘tools’ with which to discuss and debate architecture thoughtfully in all arenas of civic life.
The Image of Architects: From the Explicit to the Inexplicit
Authors: Merrick Jay 
Published: November 2019

AbstractDoes size matter? Is it possible to retain the flavour and ambition of the work of an up‐and‐coming practice after it becomes successful, or large and international? Based in London, architectural journalist and critic Jay Merrick discusses and illustrates this conundrum, looking at a few practices and how their design prima materia is continually open to question.
Effective identification of sliding mode control parameters employing linear quadratic regulator and evolutionary computation techniques
Authors: Banazadeh Afshin , Khoshrooz Azad Reza , Emami Seyyed Ali 
Published: November 2019

AbstractIn this paper, a new technique to reduce the search space in evolutionary algorithms for operative identification of sliding mode control parameters is proposed, especially in the case of a rigid satellite. The reduced domain provides a solution closer to the actual optimum at a lower computational cost. The optimized sliding mode controller provides superior performance that eliminates the need for trial‐and‐error exploration. In this approach, a linear quadratic regulator is initially designed for the equivalent linear system. In order to reduce the convergence time and computational cost, the regulator history is then used as a reference to provide optimal space for the sliding mode control parameters. Consequently, boundaries of the optimal space are fed to the genetic algorithm to optimize the control parameters. On the other hand, the particle swarm optimization uses the midpoint of the optimal space as an initial guess. The validation process is performed by tuning the sliding mode control parameters for a rigid satellite, taking into account uncertainties associated with the inertia matrix. The simulation results suggest the convergence to the near‐optimal solution, and the stability and robustness of the controller are enhanced by this technique.
Prognostic factors associated with the survival of patients with gastric adenocarcinoma: A retrospective study
Authors: Chen Cheng‐Kuo , Feng Chun‐Lung , Yu Cheng‐Ju , Peng Cheng‐Yuan , Lai Hsueh‐Chou , Cheng Ken‐Sheng , Lin Yi‐Ching , Huang Wen‐Hsin , Kao Jung‐Ta 
Published: November 2019

AbstractGastric cancer is one of the most common gastrointestinal malignancies and is a lethal cancer. This study aimed to assess the factors affecting the survival and benefit of various therapeutic modalities in gastric adenocarcinoma (GAC) patients. Between March 2006 and October 2015, 121 GAC cases were identified by pathology and divided into groups I (surgery group; n = 41), II (IIa: 19 cases without treatment; IIb: 27 cases with palliative treatment), and III (combined surgery and postoperative chemotherapy; n = 34). Furthermore, the factors affecting early (12‐month) mortality and therapeutic outcomes between these groups were assessed over the study period. Patients who underwent treatment had longer survival than those who did not (groups I+IIb+III vs IIa, P < .001); group I provided the longest survival benefit among groups over the study period (Figure 2). Analyzing 12‐month mortality, significant differences were found in groups I vs IIa (P < .001), groups I vs IIb (P < .001), groups III vs IIa (P < .001), and groups III vs IIb (P < .001) in overall patients and in groups I vs IIa (P < .001), groups I vs IIb (P = .017), groups III vs IIa (P < .001), and groups III vs IIb (P < .001) in advanced‐stage patients (Table 2). Overall, the independent factors included advanced tumor stage (hazard ratio = 8.038, P = .007), absent treatment (hazard ratio = 14.009, P = .009), higher bilirubin (hazard ratio = 8.198, P = .047), and higher CEA (hazard ratio = 3.999, P = .030). Surgery provides better survival benefit, but palliative chemotherapy could also prolong unresectable GAC patients' survival. Factors of better liver preservation, lower carcinoembryonic antigen (CEA), and less aggressive tumor condition play crucial roles in predicting patients' survival.
Coagulation mixing studies: Utility, algorithmic strategies and limitations for lupus anticoagulant testing or follow up of abnormal coagulation tests
Authors: Favaloro Emmanuel J. 
Published: November 2019

AbstractCoagulation testing underpins the investigation of hemostasis and/or monitoring of anticoagulation therapy for prevention and/or treatment of thrombosis related pathology. Assessment of coagulation results requires comparison against a normal reference range or interval (NRR/NRI). Results flagged as “abnormal” (ie, above the NRR/NRI for patients not on anticoagulant therapy), typically require further evaluation. eg, follow up or reflexive testing is used to identify the reason for prolongation, especially when supported by clinical context (eg, bleeding). Mixing tests may have utility to help identify the pathway of follow‐up testing (ie, towards investigation of factor deficiencies, or else inhibitors), and are also useful for investigation of lupus anticoagulants (LA). In general, mixing tests that “correct” tend to suggest the presence of factor deficiencies, where as those that do not correct suggest the presence of “inhibitors”. Various approaches can be used to identify correction/non‐correction, and all have strengths and limitations. Furthermore, eventual identification of causal factor deficiencies or even “inhibitors” may (eg, factor VIII or IX deficiencies or inhibitors) or may not (eg, factor XII deficiency) be clinically important. Ultimately, mixing studies performed in view of appropriate clinical scenarios (eg, bleeding patient) and for LA investigations in symptomatic patients will have best utility.
A review of sonographic thyroid volume and iodine sufficiency in children: An Australian perspective
Authors: Johnson Ayaka , Edwards Christopher , Reddan Tristan 
Published: November 2019

AbstractSonographic measurement of the thyroid gland volume is a safe and reliable method for epidemiologic studies in iodine deficiency disorders. Several factors such as age, sex and anthropometric characteristics are known to be the determinants of thyroid gland size but the most widely studied is the effect of insufficient iodine intake. Low iodine intake induces enlargement of the thyroid gland known as goitre. The assessment of urinary iodine concentration alone is not reliable as it can vary daily within individuals. Urinary iodine concentration in conjunction with sonographic thyroid gland measurements is a widely used method of thyroid gland assessment. Establishment of normative thyroid volume is essential for the assessment of iodine deficiency disorders, and studies have been conducted in several countries. These studies have shown that thyroid gland volumes are likely population‐specific even in iodine‐sufficient countries limiting the effectiveness of international reference ranges. Based on currently available data of sonographic thyroid gland volume measurements and how they vary across populations of school children, this review argues for the establishment of population‐specific reference ranges in regions such as Australia, which are now considered iodine‐sufficient.