bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuron-specific increase in lamin B1 disrupts nuclear function in Huntington’s disease
Authors: Alcalá-Vida Rafael , Garcia-Forn Marta , Creus-Muncunill Jordi , Ito Yoko , Blanco Enrique , Castany-Pladevall Carla , Crespí-Vázquez Killian , Parry Aled , Slater Guy , Samarajiwa Shamith , Peiró Sandra , Di Croce Luciano , Narita Masashi , Pérez-Navarro Esther 
Published: March 2020

AbstractLamins are crucial proteins for nuclear functionality. Here, we provide new evidence showing an involvement of increased lamin B1 levels in the pathophysiology of Huntington’s disease (HD), a CAG repeat-associated neurodegenerative disorder. Through fluorescence-activated nuclear suspension imaging we demonstrate that nucleus from striatal medium-sized spiny and CA1 hippocampal neurons display increased lamin B1 levels, in correlation with altered nuclear morphology and nucleocytoplasmic transport disruption. Moreover, ChIP-sequencing analysis shows an alteration of lamin-associated chromatin domains in hippocampal nuclei, which could contribute to transcriptional alterations we determined by RNA sequencing. Supporting lamin B1 alterations as a causal role in mutant-huntingtin mediated neurodegeneration, pharmacological normalization of lamin B1 levels by betulinic acid administration in the R6/1 mouse model of HD restored nuclear homeostasis and prevented motor and cognitive dysfunction. Collectively, our work point out increased lamin B1 levels as a new pathogenic mechanism in HD and provides a novel target for its intervention.
Examining associations between university students' mobile social media use, online self-presentation, social support and sense of belonging
Authors: Pang Hua 
Published: March 2020

PurposeThe primary objectives of the article are to systematically investigate the effects of differentiated functions of WeChat use (social use and recreational use) on university students' online self-presentation, social support and sense of belonging.Design/methodology/approachThe data were collected from a web-based survey on a sample of 485 university students in mainland China. Correlation analyses and structural equation modeling (SEM) were implemented to address the corresponding hypotheses.FindingsThe results demonstrate that the social use of WeChat is positively related to online self-presentation, whereas recreational use is unrelated to such behavior. Additionally, the findings verify that online self-presentation is a significant predictor of both social support and sense of belonging. Furthermore, online self-presentation could mediate the influence of social use of WeChat on social support and sense of belonging.Research limitations/implicationsTheoretically, the study represents an initial effort to elucidate the joint impact of differentiated functions of WeChat use and online self-presentation on social support and sense of belonging. Practically, these findings identify the crucial mediation role of online self-presentation in assisting individuals to acquire social support and promote sense of belonging.Originality/valueAlthough mobile social media has brought dramatic revolutions in interaction and interpersonal behaviors, the empirically studies regarding the potential influences of its utilization are equivocal. These outcomes may shed meaningful light on the comprehending of unique characteristics of WeChat communication and how it could impact people's psychosocial development in the digital era.
Factors affecting consumer preferences for “natural wine”
Authors: Migliore Giuseppina , Thrassou Alkis , Crescimanno Maria , Schifani Giorgio , Galati Antonino 
Published: March 2020

PurposeThe aim of this study is to understand which wine quality characteristics, consumers' attitudes and socio-demographic characteristics affect the consumers' willingness to pay (WTP) a premium price for a bottle of natural wine.Design/methodology/approachThe research is experimental and investigated the purchasing intentions of 613 Italian wine consumers within a hypothetical setting. In order to elicit WTP for natural wine, a multiple price list (MPL) in a comparison with one bottle of conventional wine, with an average price of €5 was adopted. To understand which quality attributes of wine affect the consumers' WTP for natural wine, a Tobit regression model was implemented.FindingsThe findings reveal that drink frequency and occasion, organic production method, the content of sulfites, income and the attitudes towards healthy eating and the environment are positively associated with a higher WTP for natural wine.Research limitations/implicationsThe main limitation of this study is related to both the convenient sample and the limited geographical area. However, identifying which quality attributes of natural wine are most appreciated by consumers and which attitudes affect this behaviour is fundamental in order to develop successful marketing strategies for product development and the design of advertising and communication campaigns.Originality/valueThis study is one of the first to analyse the consumer behaviour towards natural wines contributing to enrich that part of the economic literature which states that consumers have a positive attitude towards sustainable wines.
Connections between organisational culture and financial performance in Estonian service and production companies
Authors: Reino Anne , Rõigas Kärt , Müürsepp Merily 
Published: March 2020

PurposeThis paper elaborates on connections between organisational culture (OC) and financial performance in production and service companies in Estonia.Design/methodology/approachThis cross-sectional study analyses the organisational culture of 19 SMEs and large service and production companies with 2,256 respondents. The questionnaire based on the Competing Values Framework (CVF) was used to map organisational culture. Six different performance indicators from annual reports in the Estonian Business Register database were used over a four-year period. A confirmatory factor analysis and non-parametric Spearman rank correlation were applied in the study.FindingsThe authors found that OC types are connected to each other and theoretical opposites in the CVF are not mutually exclusive. Strong correlations exit between Clan and Adhocracy cultures, also confirmed by previous studies. Surprisingly, Market and Hierarchy types correlated more strongly in our sample compared to previous studies. As expected, Clan–Adhocracy and Market types exhibited a strong positive correlation with financial indicators, but contrary to the authors’ hypothesis, the Hierarchy type also had positive connections to performance indicators. The Market culture was only significantly related to performance in years when the Hierarchy type was also positively correlated with performance. Correlations that were positive in some years under investigation became insignificant in other years.Originality/valueFirst, The authors use multiple objective financial performance indicators to reveal relationships between OC and performance. Second, this study did not only rely on the managers' opinion of OC, but the sample also consists of respondents from all levels of the organisational hierarchy. Third, the authors expand on existing research into the link between OC and performance by exploring a country from the former Soviet Union (FSU), where the number of similar studies is low, but where the specific context has an impact on connections between OC and financial performance of the firms.
Family, community, and globalization: Wayuu indigenous entrepreneurs as n-Culturals
Authors: Tretiakov Alexei , Felzensztein Christian , Zwerg Anne Marie , Mika Jason Paul , Macpherson Wayne Gordon 
Published: March 2020

PurposeTo explore the cultural context of Indigenous family entrepreneurs and to apply to them the concept of n-Culturals, thus contributing to validating the concept.Design/methodology/approachInterview data collected from Wayuu entrepreneurs in La Guajira region of Colombia and from Māori entrepreneurs in the Rotorua region of New Zealand were analyzed qualitatively. The analysis primarily focused on Wayuu entrepreneurs, with the results for Māori entrepreneurs used for comparison, to help to interpret the Wayuu data.FindingsFor Wayuu entrepreneurs, family members play a range of crucial roles in enterprise operations, with the family and the kin-centered local Indigenous community emerging as an informal organization surrounding the enterprise. Family is the source of Indigenous culture, while the mainstream culture is centered on global Western business culture, rather than the culture of the country. The Indigenous entrepreneurs integrate the values of the two cultures in managing their enterprises, thus acting as n-Cultural. Māori entrepreneurs who managed enterprises with a strong Indigenous character were similar in this respect to Wayuu entrepreneurs.Social implicationsAs n-Culturals integrating the values of Indigenous culture and the mainstream culture, Indigenous entrepreneurs develop valuable traits, becoming a valuable component of the human capital in their regions, even when their enterprises fail.Originality/valueExisting research on multicultural individuals is largely limited to immigrants and expatriates. By characterizing Indigenous family entrepreneurs as n-Culturals, the present study contributes to validating the concept and opens the way for further research on how Indigenous entrepreneurs manage their multicultural identities.
When career dissatisfaction leads to employee job crafting
Authors: Wang Hai-jiang , Chen Xiao , Lu Chang-qin 
Published: March 2020

PurposeCareer dissatisfaction can be defined as an unpleasant or a negative emotional state that results from the appraisal of one’s career. This negative affective appraisal might motivate an individual to take actions to improve the situation. This paper examines career dissatisfaction as a trigger for employee job crafting in terms of altering the task and the relational boundaries of the work.Methodology/methodology/approachThe paper further theorizes that employee contextual resource (i.e., job social support) and personal resource (i.e., occupational self-efficacy) will interact with career dissatisfaction to result in job crafting. Two-wave data were collected from a sample of 246 Chinese employees.FindingsAs hypothesized, employees with career dissatisfaction exhibited the highest levels of task and relational job crafting when they received adequate support from coworkers and supervisors and were confident about their occupational abilities.Originality/valueThe findings suggest that under certain conditions employee career dissatisfaction could be transformed into proactive work behavior (i.e., job crafting).
Learning how to lead from King David?
Authors: Ben-Hador Batia , Lebel Udi , Ben-Shalom Uzi 
Published: March 2020

PurposeThe initial purpose of this research was to evaluate the effectiveness of intra-organizational training for developing leadership skills and the techniques used to assimilate course content. The study aims to understand incongruities in training and assess their impacts on training effectiveness.Design/methodology/approachQualitative research methods were used to assess a five-day course in the Israeli Defense Forces entitled, “Developing leadership skills in the spirit of the Bible.” Triangulation of data was achieved through observations, interviews and conversations with participants. Grounded theory and thematic analysis were used, respectively, to interpret and analyze the data.FindingsResults suggest that the course did not support the development of leadership skills. The analysis revealed two themes representing different domains: form (training techniques) and content (values). Combining the two themes indicates an incongruity between the declared and actual content of the training course. Further, this incongruity is supported by the training techniques that were used in this course.Practical implicationsA clash of values may ensue that leads to long-term confusion and difficulties for participants of the training course and the organization.Originality/valueThe study makes several theoretical contributions to the literature focusing on the importance of congruence between declared and real training content, and between form and content.
Does institutional ownership affect the value relevance of accounting information?
Authors: Omran Mohamed , Tahat Yasean A. 
Published: March 2020

Purpose
Drawing upon agency theory, this study aims to assess the value relevance (VR) of accounting information released by non-financial firms listed on the Kuwait stock exchange for the period of 2015-2018. Also, the influence of institutional ownership level and other explanatory variables, namely, book value per share, earnings per share, growth in assets and changes in financial leverage on share prices is examined.

Design/methodology/approach
To test the hypotheses, the Ohlson (1995) model is extended. This study uses panel data analysis and applies appropriate statistical techniques to measure empirical relationships.

Findings
The results show that the VR of accounting information released by the Kuwaiti non-financial listed firms varies over the period of 2015-2018. Book value and earnings have significant and positive effects on share prices. In recent years, the VR of book value information has been growing, while that of earnings information has been declining. Institutional ownership level has a significant and positive influence on the VR of accounting information released by the Kuwaiti non-financial listed firms. The findings confirm a positive power, signalling growth in assets regarding the share prices. However, no significant relationship between changes in financial leverage and share prices is found.

Practical implications
The findings of the study provide evidence of the linkage between VR and institutional ownership level, which promotes the understanding of the influence of institutional investors on a firm’s market value. Empirical evidence from Kuwait will have international implications and can serve as a guide for accounting researchers studying other emerging markets. Capital market regulators can provide guidelines in the form of information characteristics and elements of financial statements that need improvement. Finally, the findings assist non-financial listed firms to enhance the quality of accounting information by identifying the strengths and weaknesses in their financial reports.

Originality/value
This study extends the previous literature by investigating a relatively new set of data in more depth than that has been examined by prior research, which focusses on the relationship between accounting information and the firm’s market value.
Assessment of behavior-based performance in banking and insurance sector
Authors: Habeeb Shaad 
Published: March 2020

PurposeAlthough individual work performance (IWP) has been the subject of research by many authors, most of them have explored work performance as an outcome. However, IWP can also be viewed as conducive job behaviors. On the other hand, as employee behavior is contextual, it must be analyzed from various angles, especially in regard to a national culture of employees. In line with that, the purpose of this study was to explore the behavior-based IWP in the banking and insurance sector in New Delhi (India) by testing the original tool and modifying it into a proposed instrument for its assessment in a Hindi–English environment.Design/methodology/approachUsing a quantitative approach and exploratory and confirmatory factor analyses, specific items for the work performance assessment were selected. The specific steps involved in these processes and resulting item inclusion are discussed in detail.FindingsAlthough employees display a positive behavior-related work performance, there is a difference between private and public company workers. The study proposes modification to the original scale used.Originality/valueThe originality of the study is the assessment of IWP as a result of job behaviors in the non-Western context, in banking and insurance companies. The study has both theoretical and practical value.
Pippi's posthuman power
Authors: Lundström Markus 
Published: March 2020

PurposeThis study aims to probe the ambiguity of posthuman heroism by revisiting the remarkable story of the children's literature icon Pippi Longstocking. The purpose is to explore with Pippi a non-anthropocentric living in the more-than-human world.Design/methodology/approachThe study’s critical posthumanist analysis is empirically based on the American English translation of the Pippi book trilogy from the 1950s, as well as the Swedish TV series produced in 1969.FindingsPippi's posthuman power serves to conceptualize a move beyond the anthropocentric savior complex. The analysis exhibits a power used to defy, mock and resist authority, but always with the purpose of securing agency for Pippi and her community. This power to, rather than power over, becomes a creative force that builds a posthuman community between inorganic matter, human and nonhuman animals.Originality/valueInstead of showcasing a heroism to save our planet, Pippi animates how to relate differently to the more-than-human world. She is a productive fantasy, an idea materialized – a posthuman figuration – that extends the notion of community, opens up the demos and forcefully challenges anthropocentric normativity.
Using gamification for engaging surveyors: a case study in Statistics Indonesia
Authors: Rosmansyah Yusep , Isdiyanto Isdiyanto , Hardi Ariq Bani , Putri Atina 
Published: March 2020

Purpose
The purpose of this study is to evaluate the gamification impact on surveyors learning engagement in a case study carried out at Statistics Indonesia.

Design/methodology/approach
This study adopted the design research methodology (DRM) research framework. The problem to be solved was analyzed and structured into a DRM’s impact model. A proposed solution was hypothesized and implemented as a Web-based online learning system. Evaluative data of users were collected and analyzed in the forms of logs, questionnaires, pre-test and post-test. Further, a quantitative statistical evaluation was performed to measure the engagement and knowledge gain of surveyors after using the gamified online learning system prototype.

Findings
This research showed a positive effect on the engagement of surveyors when using the proposed gamified system. In this case study, the gamified system performed better in enhancing surveyors’ knowledge and engagement, compared to the conventional method.

Research limitations/implications
This research was based on Statistics Indonesia's case study. For future research, other case studies can be performed to generalize the gamification impacts in other organizations and other learning subjects.

Practical implications
Based on the results study, an organization such as Statistics Indonesia is recommended to involve gamification in their online learning activities because it enhances significantly surveyors' engagement and knowledge gain.

Social implications
One important implication of the research is that the proposed solution is relatively easy and inexpensive to be introduced and appended into the existing online learning system at Statistics Indonesia. If all surveyors are well equipped with proper knowledge and skill, all surveys conducted by any national statistical organization will have an accurate description and condition about any subject being surveyed in the nation. This information is important for the ruling government in deciding what the best policy and strategy are to improve the nation's condition regarding the subject.

Originality/value
The proposed gamification system showed a better online training process and learning outcome. Statistical valuation indicated that there was an increased surveyors’ academic performance in terms of engagement and knowledge gain.
Inequality of opportunity in Brazil: decomposition of the sources of injustice between 2001 and 2014
Authors: Adamczyk Willian Boschetti , Fochezatto Adelar 
Published: March 2020

PurposeThis article aims to measure inequality of income and opportunities at the national and state levels in Brazil, highlighting their acceptable and unacceptable components.Design/methodology/approachTo this end, a lower-bound estimate of income inequality (MLD) and inequality of opportunity (IOp) was developed using data from the National Household Sample Survey between 2001 and 2014.FindingsIt shows that the disparity of income measured by the MLD decreased 26.7 percent, while IOp measured by the IOp decreased 25.6 percent during that period. The decline in total inequality can be attributed to a 48.5 percent decrease of its unfair component and 51.5 percent decrease of its fair component. The average income of the most disadvantaged group (non-white women working in the informal sector) is shown to be only 29.5 percent of the income of the most advantaged group (formally employed white men). The groups at the greatest disadvantage were most benefited by the increase in income.Originality/valueBeyond comparisons among countries, analysis at the subnational level make it possible to identify how the process that generates inequality acts in each state, revealing patterns undetected in the aggregate analysis. Its decomposition generates two products that are useful to policy-makers. The first is a base estimate of the degree of IOp present in society, which may be expressed as an indicator of the degree of IOp. The second examines the portion of total inequality attributable to IOp.
Interpreting the dynamic performance effect of intellectual capital through a value-added-based perspective
Authors: Ting Irene Wei Kiong , Ren Chunya , Chen Fu-Chiang , Kweh Qian Long 
Published: March 2020

PurposeThe question of whether intellectual capital (IC) is beneficial to firm performance is debatable because of the diverse effects of IC and its components on firm performance. Building on the concept of pay–performance relation, this study aims to provide new insights into how changes in IC affect changes in firm performance.Design/methodology/approachData envelopment analysis is employed to measure firm performance, and value-added intellectual coefficient (VAIC™) is selected to evaluate the IC and its components, namely human capital efficiency (HCE), structural capital efficiency (SCE), and capital employed efficiency (CEE). Ordinary least squares regression is applied to study the relationship between changes in IC and changes in firm performance using 6,408 firm-year observations of electronics companies listed in Taiwan from 2006 to 2017.FindingsEmpirical results suggest that IC efficiency and CEE significantly and negatively affect firm performance, thereby suggesting a contradictory common sense with the resource-based view on the beneficial effects of IC. However, changes in IC efficiency and HCE are significantly and positively related to changes in firm performance, including changes in firm efficiency and sales growth.Practical implicationsThis study suggests that managers should continuously pay attention to adjusting their IC, especially human capital (HC) for better decisions that help grow firm performance. Moreover, investors can grasp how sensitive firm performance is to IC.Originality/valueThis study argues the relationship between IC and firm performance in the same vein as a pay-for-performance link, suggesting that future studies should account for increases or decreases in IC.