bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long‐term outcomes of artificial urinary sphincter in female patients with spina bifida
Authors: Gasmi Anis , Perrouin‐Verbe Marie‐Aimée , Hascoet Juliette , Bey Elsa , Jezequel Magali , Voiry Caroline , Perrouin‐Verbe Brigitte , Gamé Xavier , Manunta Andrea , Lenormand Loic , Capon Grégoire , Peyronnet Benoit 
Published: November 2020

AbstractAimsTo report the long‐term functional outcomes of artificial urinary sphincter (AUS) implantation in female patients with spinal dysraphism and stress urinary incontinence (SUI) related to intrinsic sphincter deficiency (ISD).MethodsThe charts of all spina bifida female patients with SUI due to ISD who underwent AUS (AMS 800) implantation between 2005 and 2019 at three academic departments of urology were retrospectively reviewed. Reoperation was defined as either revision or explantation of the AUS device. Reoperation‐free survival of the AUS device was estimated using the Kaplan–Meier method. Continence status as per patients' subjective assessment was categorized as follows: complete continence (no pads), improved continence, unchanged SUI or worsened SUI.ResultsTwenty‐three patients were included, 69.6% were self‐catheterizing. The median follow‐up was 14 years. Median time to first reoperation was 10 years. Survival rates without reoperation were 85.9%, 41.8%, 34.6%, and 20.9% at 5, 10, 15, 20 years, respectively. Survival rates without AUS explantation were 90.7%, 66.3%, 55.2%, and 41.4% at 5, 10, 15, 20 years, respectively. None of the patients who underwent device explantation had a new AUS implanted. The only predictive factor of reoperation‐free survival was the type of spinal dysraphism (hazards ratio = 3.60 for closed vs. open dysraphism; p = .04). At last follow‐up, 17 of the 23 patients were fully continent (73.9%).ConclusionAUS in female patients with spina bifida may be associated with satisfactory long‐term functional outcomes and a high reoperation rate. The median time to first reoperation was similar to what is reported in the male AUS literature (10 years).
“Make no little plans”: Impactful research to solve the next generation of transportation problems
Authors: Agatz Niels , Hewitt Mike , Thomas Barrett W. 
Published: November 2020

AbstractThe transportation science research community has contributed to numerous practical and intellectual innovations and improvements over the last decades. Technological advancements have broadened and amplified the potential impacts of our field. At the same time, the world and its communities are facing greater and more serious challenges than ever before. In this paper, we call upon the transportation science research community to work on a research agenda that addresses some of the most important of these challenges. This agenda is guided by the sustainable development goals outlined by the United Nations and organized into three areas: (1) well‐being, (2) infrastructure, and, (3) natural environment. For each area, we identify current and future challenges as well as research directions to address those challenges.
Synergism between Angiotensin receptors ligands: Role of Angiotensin‐(1‐7) in modulating AT2R agonist response on nitric oxide in kidney cells
Authors: Patel Sanket , Hussain Tahir 
Published: November 2020

AbstractAngiotensin‐(1‐7), an endogenous agonist for the MasR, has been shown to interact with ang‐II AT1R and AT2R. Earlier we showed a physical and functional interaction between MasR and AT2R in response to their respective agonists ang‐(1‐7) and C21. Moreover, ang‐(1‐7) is cardio‐protective via AT1R and alters ang‐II function. Such complex nature of ang‐(1‐7) function is not clearly understood, particularly in relation to its functional interaction with these receptors. We tested how ang‐(1‐7) affects AT2R function by utilizing HK‐2 cells. The HK‐2 cells were treated with a wide range of concentrations of angiotensin receptor agonists. The generation of NO• in response to agonists was determined as a readout and subjected to Bliss definition (δ score) to assess the nature of functional interaction between these receptors. Preincubation with ang‐(1‐7) followed by incubation with endogenous AT1R/AT2R agonist ang‐II (δ = 162) or selective AT2R agonist C21 (δ = 304) synergized NO• formation. The synergism was also observed when the order of incubation with ang‐(1‐7)/C21 was reversed (δ = 484), but not when the cells were simultaneously incubated with a mixture of ang‐(1‐7) and C21 (δ = 76). The synergism with nonpeptidic MasR agonist AVE0991 followed by C21 (δ = 45) was minimal. Ligand binding experiment suggested the binding of ang‐(1‐7) with these three receptors. However, the synergism observed with ang‐(1‐7) and ang‐II/C21 was sensitive to the antagonists of AT2R (PD123319) and AT1R (candesartan), but not MasR (A779). Ang‐(1‐7) at lower concentrations synergies the AT2R function in an AT1R‐dependent but MasR‐independent manner. This phenomenon may have a physiological significance.
disturbance attenuation for a class of Lipschitz nonlinear systems with large input delay
Authors: Wang Chunyan , Li Yunhan , Wang Jianan , Wang Dandan 
Published: November 2020

AbstractThis article investigates disturbance attenuation problem for a class of Lipschitz nonlinear systems subject to unknown sensor disturbances/faults and large input delay. First, the Artstein model reduction method is applied to deal with the input delay and a descriptor observer is constructed to estimate the predicted state and sensor faults simultaneously. Then, a finite‐dimensional controller is designed, which gets rid of the distributed delays in traditional reduction controllers and is easy to be implemented. By using Lyapunov‐Krasovskii functionals, sufficient conditions are derived to guarantee the disturbance attenuation. Finally, a numerical simulation is given to demonstrate the effectiveness of the proposed method.
Calcium Poisoning Mechanism of Cu‐SAPO‐18 for Selective Catalytic Reduction of NOx with Ammonia
Authors: Gao Qi , Ye Qing , Han Shuai , Dai Hongxing 
Published: November 2020

AbstractTo investigate the effect of Ca poisoning on Cu‐SAPO‐18, a series of samples with different Ca amounts were prepared by the impregnation method, and their NH3‐SCR activities were evaluated. When the Ca amount was 0.8 mmol/gcat, NO conversion at 350 °C was 40.6% (lower than that over the fresh Cu‐SAPO‐18 sample), which shows that the catalytic deNOx performance was significantly decreased after Ca poisoning. Ca poisoning did not have a great influence on the structure of Cu‐SAPO‐18, but the formed CaO blocked part of the micropores, which reduced surface area and micropore volume, and further reduced accessibility of the active sites and surface acidity of the sample. The total amount of the isolated Cu2+ species decreased from 62.83 μmol/gCu‐SAPO‐18 to 23.45 μmol/g0.8Ca‐Cu‐SAPO‐18, which resulted in conversion of the isolated Cu2+ species to Cu2O in the sample after the addition of Ca. In addition, the substitution of Ca2+ with H or Cu2+ in Si–O(H)–Al or Si–O(Cu2+)–Al to form the Si–O(Ca2+)–Al species decreased amounts of the Lewis and Brönsted acid sites, which might be the important reasons for the drop in catalytic activity. Both the Eley–Rideal (E–R) and Langmuir–Hinshelwood (L–H) reaction mechanisms existed over the samples in the NH3‐SCR reaction, but the L–H reaction mechanism was dominant. The catalytic mechanism over the sample did not change, but the reaction was slower after Ca poisoning.
Morphology Modulated Photocatalytic Activity of CeO2 Nanostructures for Selective Oxidation of Biobased Alpha‐Pinene to Oxygenates
Authors: Mavuso Mlungisi A. , Makgwane Peter R. , Ray Suprakas Sinha 
Published: November 2020

AbstractThe effective Ce3+/Ce4+ redox and oxygen mobility of CeO2 induced by tunable nanostructure morphology has attracted a great interest in photocatalytic organic synthesis. Herein, we report on the microwave‐assisted synthesis of CeO2 with nanoparticles (NPs), nanorods (NRs) and nanocubes (NCs) morphologies. The optical‐electronic properties of the nanostructure CeO2 catalysts varied relatively with the respective morphologies. Ce‐NPs catalyst showed a significant blue shift while a red shift was observed for Ce‐NCs and a slight blue shift for Ce‐NRs. The Ce‐NRs and Ce‐NPs showed high charge recombination suppression, which was due to the formation of surface defects associated with dislocations, steps and oxygen vacancies (Vo) as elucidated from the photolumiscence, X‐ray photoelectron spectroscopy and electron paramagnetic resonance results. The surface oxygen defects populated with reactive superoxide oxygens of Ce‐NRs and its high surface showed better photocatalytic activity for oxidation of alpha‐pinene to pinene oxide, verbenol and verbenone as major products. A pinene conversion of 33.6 % to pinene oxide with the selectivity of 54.3 % was achieved with Ce‐NRs. The effective photocatalytic activity of the Ce‐NRs was attributed to its enhanced efficient charge recombination suppression and oxygen vacancies. Ce‐NRs catalyst was recyclable without any significant loss of its initial photoactivity.
Sensing of Phosphate and ATP by Lanthanide Complexes in Aqueous Medium and Its Application on Living Cells
Authors: Sahoo Jashobanta , Jaiswar Santlal , Jena Himanshu Sekhar , Subramanian Palani S. 
Published: November 2020

AbstractThe design of coordination complexes as synthetic receptors for selective sensing of inorganic anions and nucleoside phosphates in aqueous medium under physiological conditions are important for biomedical research and drug delivery. In this work, two phenanthroline‐based luminescent lanthanide complexes; EuLCl3 (1) and TbLCl3 (2), were explored for sensing anions such as HPO42−, SO42−, CH3COO−, I−, Br−, Cl−, F−, NO3− and HSO4− with HPO42− exhibiting the strongest emission. Nucleoside phosphates such as ATP, ADP and AMP could be also detected. Both complexes 1 and 2 are highly selective sensing ATP at physiological pH. The detection limit and their corresponding Stern‐Volmer quenching constant were calculated for ATP as in the range of 0.2 μM–1 mM and 2.0×106 M−1. Complex 1 was applied as a staining agent to study alga cells (Microspora unialgal filamentous cell). The result shows that the ligand L causes a severe cytotoxic effect and induces the cell damage.
Recent Progress in Synthesis and Applications of Tunable Materials and Nanomaterials Based on Organic Salts
Authors: Kaur Pawanpreet , Chopra Harish K. 
Published: November 2020

AbstractGUMBOS (group of uniform materials based on organic salts) are a new class of solid organic ionic materials that shared similar properties as that of ionic liquids, but have a wider range of melting points from 25 °C to 250 °C. A large number of combinations have been made to design and synthesize multifunctional GUMBOS with tuned properties that are encouraged to explore these organic materials for various applications. Further, nanomaterials can be fabricated from GUMBOS through various reliable synthetic approaches. These nanomaterials have known as ‚nanoGUMBOS‘ that possessed advantageous properties at the nanoscale and can be used for target applications. Besides, the size, shape, and uniformity of nanomaterials can be tuned by varying different experimental parameters, and synthetic routes.This review is divided into two parts and presents all the published data regarding GUMBOS and nanoGUMBOS. The first part enclosed the synthesis of GUMBOS as well as their potential applications in the field of analytical, optoelectronics, biology, and sensor technology. In the second part, the synthesis of nanoGUMBOS using different methods and their applications in the field of cellular imaging, optoelectronics, catalysis, enantiorecognition, and sensor technology will be highlighted.
Study on Characterization and Coke Compositions of Deactivated 5 A Molecular Sieve for Adsorption Separation of Industrial Naphtha
Authors: Liu Jiaxu , Zhu Shenjie , Zhang Lin , Liu Zongjian , Cui Qun , Wang Haiyan 
Published: November 2020

AbstractThe deactivation causes and coke compositions of the deactivated 5 A molecular sieves (5A−E) used in the liquid phase adsorption separation process for industrial naphtha were analyzed. The results showed that 5A−E existed 14 species of C10∼C11 benzene series, naphthalene series and indans (main components of industrial corrosion inhibitor), which formed coke to block 4.4–4.9 Å micropores of 5 A−E. The coke content was ∼3.72 % and there had a strong exothermic peak at 271 °C on the surface of 5A−E. The static adsorption capacity of fresh 5 A molecular sieves for n‐hexane reduced by 24.6 % within 90 min in the isooctane/n‐hexane mixed solution containing 400 ppm industrial corrosion inhibitor. It indicated that trace corrosion inhibitor would be deposited on the surface of 5 A molecular sieves during industrial long‐term operation, resulting in slow deactivation of 5 A molecular sieves. It can provide the guidance for industrial production of liquid phase adsorption separation process of naphtha.
Tremella‐shaped TiCN Nanosheets as Anode mAterials of Lithium‐Ion Batteries
Authors: Zheng Guojun , Gao Xinran , Xing Zheng , Hong Haiping , Ju Zhicheng 
Published: November 2020

AbstractTransition metal carbides and nitrides have attracted more and more attention as excellent mAterials in the field of electrochemical energy storage. Here, we have taken a different approach to synthesize tremella‐like unique titanium carbonitride (TiCN) nanosheets by hydrothermal method and high temperature solid phase sintering. Through microscopic characterization, the final products are gathered together in the form of nanosheets or ribbons like individual petals, which creates mAny ion transports channels and voids. In addition, two different products were prepared by changing the basic conditions of the precursor. After comparing the microstructures of the two groups of products and their precursors, TiCN‐5 mol was mAinly studied. In terms of electrochemical performance, TiCN‐5 mol nanosheets possess higher reversible specific capacity (476mAhg−1 after 80 cycles) and excellent coulombic efficiency (98.5 % after 80 cycles) and superior rate performance up to 5000 mAg−1 (100 % of its capacity at 100 mAg−1 rate) compared to TiCN‐10 mol. The enhanced electrochemical performance is primarily due to the high specific surface area and low ion diffusion barrier of the TiCN nanosheets, which provides high ion electrical conductivity and plays an important role in reducing large volume expansion during prolonged cycling.
Dandelion‐like CoO/Co3O4/Carbon Composites as Anode Materials for a High‐Performance Lithium Ion Battery
Authors: Huang Run , Zhou Rihui , Wang Li , Zhu Yongmei 
Published: November 2020

AbstractHere, dictyophora indusiata is used as raw materials, through simple hydrothermal reaction and unique triethylamine (TEA) combustion to prepare dandelion‐like CoO/Co3O4/dictyophora indusiata‐derived carbon (DIC) composites. The CoO/Co3O4/DIC are characterized by scanning electron microscopy, transmission electron microscopy, X‐ray powder diffractometer, X‐ray photoelectron spectroscopy, Raman spectroscopy, N2 adsorption/desorption isotherm and thermogravimetric analysis, The CoO/Co3O4/DIC shows three‐dimensional network and porous structure, which facilitates the electron transport, enlarges the contact area with the electrolyte, and effectively alleviates the damage from volume expansion of CoO/Co3O4 during discharge/charge process. During TEA combustion process, the DIC is crosslinked successfully to form a stable N‐doped networks. When used as a negative electrode material for lithium ion batteries, it can still provide a high capacity of 545 mA h g−1 at a current density of 1000 mA g−1 after 250 cycles. The readily available and renewable biomass material is of great significance for achieving efficient electrochemical energy storage.
Facile Fabrication of Fe3O4@poly(acrylic) Acid Based Ferrofluid with Magnetic Resonance Imaging Contrast Effect
Authors: Le The Tam , Nguyen Hoa Du , Nguyen Thi Ngoc Linh , Phan Thi Hong Tuyet , Ho Dinh Quang , Nguyen Thien Vuong , Le Thi Thu Hiep , Vuong Thi Kim Oanh , Le Khoa Hai , La Duc Duong , Le Trong Lu , Tran Lam Dai 
Published: November 2020

AbstractMagnetic resonance imaging (MRI) has emerged as one of the most promising techniques, which employs nanoscience and imaging technology, for early diagnosis of the cancers. In this work, magnetic nanoparticles of Fe3O4@ poly(acrylic) acid (PAA) were synthesized using a low cost thermal decomposition method from iron ions precursor and utilized as a signal agent for MRI imaging. The Fe3O4 magnetic nanoparticles obtained from FeCl2.4H2O precursor at the reaction temperature of 315 °C in 1‐octadcene solvent are of spherical shape with average diameter of 8.4 nm and high saturation magnetization (Ms) of 60.05 emu/g. After phase transferred with PAA, the magnetic Fe3O4@PAA fluid is highly stable in a wide range of pHs solution (5 ‐ 9) and wide range of NaCl concentrations (50 ‐ 300 mM) with zeta potential of −35.7 mV. The prepared Fe3O4@PAA fluid showed noncytotoxicity to the Hep‐G2, MCF‐7, RD cancer cell line and Vero healthy cell line. MRI in‐vitro results showed that transverse relaxation rate r2 was around 158.4 mM−1s−1 and the signal intensity was not affected by the pHs solution and NaCl concentrations. In‐vivo test on rabbit revealed the clear observation of rabbit's body parts after injection of the Fe3O4@PAA magnetic fluid with retention time of 90 minutes in the body.
Synthesis and Anti proliferative Activity of New N‐Pentylquinoxaline carboxamides and Their O‐Regioisomer
Authors: Aboelmagd Ahmed , Alotaibi Saad H. , El Rayes Samir M. , Elsayed Gomaa M. , Ali Ibrahim A. I. , Fathalla Walid , Pottoo Faheem H. , Khan Firdos A. 
Published: November 2020

AbstractWe have designed a series of quinoxalinepeptidomimetic derivatives based on our previous reported scaffold in attempt to find a promising lead compound. Quinoxaline derivatives; N‐alkyl‐3‐(3‐oxo‐4‐pentyl‐3,4‐dihydro‐quinoxalin‐2‐yl)‐propanamides and methyl 2‐[3‐(3‐oxo‐4‐pentyl‐3,4‐dihydro‐quinoxalin‐2‐yl)propanamido]alkanoates and their O‐regioisomers were prepared by alkylation of the ambient nucleophile methyl 3‐(3‐oxo‐3,4‐dihydroquinoxalin‐2‐yl)propanoate with pentyl bromide to give the corresponding N‐ and O‐pentylquinoxaline ester derivatives. The N‐ and O‐pentyl‐quinoxaline ester derivatives gave the desired products by the reaction with amines and amino acid esters via azide coupling method. We have examined the anti proliferative activity of the 35 different synthesized compounds on human HCT‐116 and HEK‐293 cell lines. Out of 35 screened derivatives, 14 active compounds exhibited inhibitory action on the HCT‐116 cells with IC50 values ranging from 0.43 mM to 2.62 mM. We have also examined the impact of these active compounds on cancer cells nucleus and caspase 3 activity, we have the found that active compounds also increased in the caspase 3 activity which led to programmed cell death of cancer cells. We have also examined the impact of 35 compounds on the normal and non‐cancerous cells (HEK‐293) and we have found these active compounds did not cause any cytotoxic effect on the normal cells.
Tracking and Recovery of Metal Desorption from Organized Films of Polyguanamine Derivatives having Cyclic Moieties
Authors: Fukushi Keito , Yamaguchi Junto , Shibasaki Yuji , Fujimori Atsuhiro 
Published: November 2020

AbstractMetal desorption behavior of polyguanamine derivatives having cyclic moieties (c‐PGs), with metal‐scavenging abilities, organized into molecular films was investigated, and a recovery technique was realized. Cadmium (a toxic metal), palladium (a precious metal), and neodymium (a rare earth metal) were studied, along with sodium (a cationic metal). A monolayer of c‐PGs forming on an aqueous metal solution surface effectively scavenges cations from the subphase owing to the relative basicity of the cyclic moiety. X‐ray photoelectron spectroscopy revealed that cadmium and palladium (both divalent cations) were desorbed by simple 30–60 min ultrasonication of their Langmuir–Blodgett multilayers. Conversely, the desorption of neodymium, a trivalent cation, was very slow. Sodium, a monovalent cation, was difficult to collect. Its valence and monolayer condensation on the aqueous sodium buffer were remarkable, indicating that coordinated sodium ions escape during the monolayer condensation.
Preparation and Characterization of Sodium Alginate and Polyquaternium‐10 Hollow Microcapsules by a Layer‐by‐Layer Self‐Assembly Technique
Authors: Wang Min , Zhang Huihui , Shao Huili , Yang Gesheng 
Published: November 2020

AbstractNovel micro‐scaled hollow capsules were obtained by consecutively adsorbing oppositely‐charged polyelectrolytes of sodium alginate (ALG) and polyquaternium‐10 (PQ‐10) on biocompatible porous calcium carbonate (CaCO3) microspheres, followed by the subsequent removal of the CaCO3 template using acetic acid. The properties of the microcapsules were characterized at various stages of the preparation procedure by using a zeta potential analyzer, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermogravimetric analysis (TG) and confocal laser scanning microscopy (CLSM). The results demonstrated that ALG and PQ‐10 were successfully assembled on the surface of the CaCO3 microspheres, and the resulting hollow microcapsules exhibited spherical morphology with typical folds by SEM observations. Furthermore, TEM observations indicated that the average thickness of the monolayer film was ∼1–2 nm, and CLSM results revealed that the microcapsules possessed selective permeability for different charged molecules.
Template Preparation of Copper‐Based Chalcogenides and their Electrochemical Performance for Li‐ion Batteries
Authors: Chen Yanfen , Pei Quan , Liu Xiaolin , Chen Xiuli , Rao Xianfa , Li Dong , Chen Guoxin , Zhong Shengwen 
Published: November 2020

AbstractTransition‐Metal chalcogenides have high Li‐ion storage capacity and considerable cycle performance, which has attracted great interest from researchers and is expected to replace graphite materials in the field of Li ion batteries. The purpose of this paper is to find a low‐cost and ecofriendly method for producing copper‐based chalcogenides as anodes with a high capacity and long cycling stability for lithium ion batteries. In our strategy, carbon nanospheres are used as templates to prepare precursor Cu(OH)2@C. Then, the Cu(OH)2@C is converted into copper‐based chalcogenides by different routes. The structure and morphology of the as‐synthesized materials is characterized by the X‐ray diffraction, scanning electron microscopy and transmission electron microscopy. The anode electrochemical performance of the samples was investigated by galvanostatic cycling (GC) vs. Li/Li+ at different current rate. Compared to other copper chalcogenides, the synthesized copper oxide shows better charge/discharge cycle stability and rate performance. Its capacity retention is as high as 128 % at a current density of 0.5 C after 200 cycles.
Atropisomerism inN1‐aryl Substituted 3,4‐dihydropyrimidin‐2(1H)‐thiones
Authors: Gonçalves Itamar L. , Davi Leonardo , Machado das Neves Gustavo , Porto Kagami Luciano , Garcia Solange C. , Oliveira Battastini Ana M. , Figueiró Fabrício , Faria Santos Canto Rômulo , Merlo Aloir A. , Eifler‐Lima Vera L. 
Published: November 2020

AbstractDihydropyrimidinone/thiones (DHPMs) are heterocycles widely explored due to their ability to interact with different pharmacological targets. We report herein the C–N axial chirality in a DHPM scaffold with the presence of various substituents at theortho‐position of the aromatic ring linked to the N1. This structural feature produced atropisomerism due to the restricted rotation around the C−N bond. The atropisomerism in DHPMs was investigated by NMR, HPLC, andin silicoexperiments. The effect of the solvent, microwave radiation, temperature, and substituent at theorthoposition on the selectivity of the reaction was examined.