bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Report: 18F-FDG PET/CT in Nonfunctioning Adrenocortical Carcinoma Relapse
Authors: Martinovich A. A. , Mikhaylov A. I. , Meshcheriakova N. A. , Dolgushin M. B. 
Published: April 2020

Case report of adrenocortical carcinoma recurrence after adrenalectomy and combined treatment.We report the case of a 46 year old man with silent adrenal mass. Imaging showed a large left adrenal mass with no evidence of distant metastasis. Complete surgical excision of the tumor was performed. After 5 years after surgical treatment, a local relapse of the disease was detected according to the results of CT, followed by PET/ CT with 18F-FDG — no evidence of distant metastases were detected. After complex treatment metastases were diagnosed by follow up PET/CT.This case report demonstrates possibilities of PET/CT with 18F-FDG in determination of adrenal mass malignancy and in cases of recurrent adrenocortical cancer, in cases of metastatic lesions.
Signa et tituli dans les Alpes maritimae : l’exemple des stèles funéraires en forme de porte
Authors: Morabito Stéphane 
Published: April 2020

Cet article s’est attaché à un ensemble de cinq stèles cohérent et original des Alpes maritimes : les stèles en forme de porte. La présence de symboles militaires gravés sous les inscriptions, appréciée également dans le milieu militaire du littoral dalmate, permet à l’auteur de remonter une des pistes possibles qui expliquerait l’origine de ce motif iconographique : la présence d’auxiliaires originaires de Dalmatie dans la province des Alpes maritimes.
Broken Glass: Sylvia Gellburg's Mirror Stage
Authors: Marino Catherine 
Published: April 2020

Abstract
This article explores Sylvia Gellburg's awakening at the end of Arthur Miller's Broken Glass through the lens of “méconnaissance” (misrecognition), a term coined by Lacan and applied by feminine theorist Kathleen Woodward to a second “mirror stage” of aging. Lacan's mirror stage describes how a human infant creates a fixed sense of an ideal self, an integrated “whole” albeit illusionary, toward which the individual strives his or her entire life. Woodward writes that many postmenopausal women experience a “misrecognition” of their aging selves in the mirror or in photographs. While this is often a traumatic experience, she argues that it opens the possibility for a second mirror stage, where the individual can reimagine the self. The death of the illusion of the ideal allows for greater self-awareness and a more authentic life. I argue that Sylvia's gradual awakening in the play can be viewed through the lens of a second mirror stage and also is linked to Phillip's self-realization.
Análise dos indicadores relativos à saúde da gestante de um município do sul do Brasil
Authors: Jacobi Elton Rogerio Teixeira , Gomes Clandia Maffini , Jacobi Luciane Flores 
Published: April 2020

O objetivo deste estudo consiste em verificar a situação do Município de Santa Maria em relação ao cumprimento das metas estabelecidas no Programa de Humanização no Pré-natal e Nascimento. No presente trabalho foram utilizados os dados disponíveis no sistema SISPRENATAL, referente ao Município de Santa Maria - RS, no período compreendido entre 2006 e 2013, contabilizando 11.000 gestações. As variáveis analisadas foram: idade da gestante; idade gestacional de ingresso ao pré-natal; número de consultas realizadas; exames realizados e realização da consulta puerperal. Do total de gestações avaliadas, o pré-natal foi iniciado com idade gestacional superior a 17 semanas em 28,12% delas, em 21,22% foram realizadas 6 ou mais consultas e com exceção dos exames de Urina, Glicemia, HB e Ht em 1ª rotina, todos os demais atingiram menos de 50% das gestações analisadas. Observou-se que o Município em análise, não está atendendo aos indicadores mínimos preconizados pela legislação em vigor.
La prescriptora publicitaria de belleza en España y sus mecanismos de representación: Análisis a través de la revista Telva
Authors: Vicente Fernández Pilar , Arroyo Almaraz Isidoro 
Published: April 2020

Purpose: The social and cultural dimension of the commercial message attests to the link between advertising and the historical context in which it takes place, affecting women and communication from various perspectives. Therefore, this research aims to analyze the evolution of the image of women in advertising according to their role as prescribers of commercial messages related to brands and beauty products in the last 56 years of the History of Graphic Advertising in Spain.

Design / Methodology / Approach: An exploratory and descriptive methodology is used via the technique of content analysis that applies to all the graphic advertisements of the Beauty and Hygiene sector inserted during the months of December in Telva, whose choice is based on the fact that it is the oldest high-end women’s magazine in the country of research. The sample covers from the year 1963, date of the first issue, until 2018, having studied 1020 graphic advertisements.

Results: There were differences in the treatment of the figure of women as advertising prescriber according to the decade analyzed, being common, however, a marked aspirational and connotative character in preaching as well as a small role for the male participant as a companion in the work of prescribing. The solidity of the feminine imprint is concluded in a women’s communication aimed at women.

Research limitations/implications: The case is restricted to the graphic medium journals, and it is possible to propose future complementary research on comparative analyses between various media and different sectors of business activity.

Originality/value: The extent and scope of the time of study covered stand out, allowing one to delve into the fundamentals of the advertising prescription prevailing today as well as highlighting the most outstanding particularities of the prescription of brands and cosmetic products.
Extracting and Studying the Factors Affecting the Tanning Material in the Garad Pods
Authors: Eltom Egbal , Abdalla Gurashi 
Published: April 2020

In this study the chemical structure of Garad tan pods (acacia – nilotica) were determined and investigated. It was found that Garad tan is a polyphenol type of structure and consequently it has an antiseptic effect, it is also used as pretaning and retaning agent.
Garad pods need to be disintegrated and ground into fine grains of very small diameter. In its powder form it cannot be used in tannage as the grains may block the sewage, hence, it has to be leached, concentrated and spray dried.
The factors that affect leaching of the tannins from Garad pods were studied, there are: Temperature, solvent to solid ratio, degree of mixing and time were specified and factorial experiments were designed to study the effect and significance of these factors. The levels of these factors were (30 and 50°C), (1:5 and 1:7), (with and without) mixing and (25 and 50) minutes respectively. All these factors were found to be very significant.
Having determined the optimum factors their levels trials were carried out at the following levels:
Temperature: 50°C
Solid to solvent ratio: 1:7
Degree of mixing: With mixing
Time: 50 minutes
The trials made at these conditions were found to be efficient with high yield of the extract. The extract produced was concentration which makes it ready for use in pertannage or retannage or for spray drying to powder.
Insulin resistance in clomiphene responders and non‐responders with polycystic ovarian disease and therapeutic effects of metformin
Authors: Parsanezhad M.E , Alborzi S , Zarei A , Dehbashi S , Omrani Gh 
Published: July 2002

AbstractObjectives: To evaluate the clinical features, endocrine and metabolic profiles in clomiphene (CC) responders and non‐responders with polycystic ovarian disease (PCOD), and to examine the effects of metformin (MTF) on the above parameters of CC resistance. Methods: A prospective clinical trial was undertaken at the infertility division of a university teaching hospital. Forty‐one CC responders were selected and their hormonal and clinical features were determined. Forty‐one CC‐resistant PCOD women were also selected and clinical features; metabolic and hormonal profiles before and after treatment with MTF 1500 mg/day for 6–8 weeks were evaluated. Women who failed to conceive were treated by CC while continuing to take MTF. Results: CC responders had higher insulin levels while non‐responders were hyperinsulinemic. Menstrual irregularities improved in 30%. Mean±S.D. area under curve of insulin decreased from 297.58±191.33 to 206±0.1 mIU/ml per min (P=0.005). Only 39.39% ovulated and 24.24% conceived. Conclusion: PCOD is associated with insulin resistance (IR) particularly in CC‐resistant women. Insulin resistance and androgen levels are significantly higher in obese patients. MTF therapy improved hyperandrogenemia, IR, and pregnancy rate.
Risk factors associated with endometrial polyps in abnormal uterine bleeding
Authors: Bakour S.H , Gupta J.K , Khan K.S 
Published: July 2002

AbstractObjectives: To evaluate the significance of various risk factors associated with endometrial polyps in women with abnormal uterine bleeding. Methods: A prospective cohort study of 248 consecutive patients evaluated for abnormal uterine bleeding in a Rapid Access Ambulatory Diagnostic (RAAD) clinic was carried out from 1996 to 1997. Endometrial polyps were diagnosed using outpatient hysteroscopy and their histological nature was confirmed in all patients by performing inpatient polypectomy. Multivariate logistic regression modeling was used to evaluate the effects of age, parity, menopausal status, hormone replacement therapy and tamoxifen treatment on the occurrence of polyps. Results: In an analysis adjusted for the effects of age, parity and menopausal status, tamoxifen treatment was associated with endometrial polyps (adjusted odds ratio 11.21, 95% confidence interval 2.70–46.46, P=0.0009) but hormone replacement therapy was not (adjusted odds ratio 1.48, 95% confidence interval 0.68–3.20, P=0.32). Conclusion: Our study confirmed that tamoxifen is associated with endometrial polyps. However, it rejects the hypothesis that hormone replacement therapy is a risk factor for endometrial polyps.
Improving emergency obstetric care at a state referral hospital, Kebbi State, Nigeria
Authors: Oyesola R , Shehu D , lkeh A.T , Maru I ,   (The Sokoto PMM Team)
Published: July 2002

AbstractPreliminary studies: An inventory at Birnin Kebbi Specialist Hospital in Nigeria revealed poor capacity in emergency obstetric care and excessive delays. Focus group discussions among community members emphasized poor services as a reason for not seeking care. Interventions: During 1992–1993, several specialist obstetricians visited the hospital. They provided training to general physicians and midwives and care to patients, and stayed approximately five weeks each. An obstetric first‐aid box with essential drugs and supplies was introduced. Midwives were trained in recognition and management of obstetric complications. Subsequent community interventions focused on improving access and reducing delay in seeking care. Results: The number of cesarean sections performed increased from 101 in 1990 to 131 in 1995. The case fatality rate among women with complications dropped from 22% to 5% over the same period. The number of women with complications seeking treatment in the hospital increased from 200 in 1990 to 227 in 1994, and then declined to 152 in 1995. Costs: The cost of improvements at the hospital was approximately US$12 300, with 10% contributed from government sources. Conclusion: Improving hospital obstetric services is feasible and affordable. Better services, however, may not be sufficient to reverse declining hospital utilization related to worsening economic conditions. © 1997 International Federation of Gynecology and Obstetrics
Ten years' experience with clozapine in treatment-resistant schizophrenic patients: Factors indicating the therapeutic response
Authors: Alvarez E , Barón F , Perez-Blanco J , Puigdemont José Soriano D , Masip C , Perez-Solá V 
Published: July 2002

SummaryA prospective study in treatment-resistant schizophrenic patients was performed over 10 years to evaluate the therapeutic response to clozapine and the variables related to this treatment. Eighty schizophrenic and schizoaffective patients (according to Diagnostic and Statistical Manual [DSM]-IIIR criteria), considered as refractory (previously resistant to at least two different typical neuroleptics), were studied. The average dose of clozapine was 267 mg/d. The clinical variables considered were: Brief Psychiatric Rating Scale (BPRS), number of admissions before and after clozapine treatment and the Strauss-Carpenter scale as measures of efficacy; Premorbid Adjustment Scale (PAS), to assess personal and social adjustment before illness; Karolinska Personality Scale (KPS) to assess stable traits of personality; and the Simpson-Angus scale as a measure of extrapyramidal symptoms. Sixty percent of patients showed a significant improvement after clozapine treatment. Side-effects were mild and well tolerated, with no cases of haematological disturbance and only five withdrawals because of adverse events. The severity of the episode, according to BPRS score and anxiety as a personal trait, are related to good prognosis. Other relationships between improvement and clinical and demographic variables are discussed.
Organizing ODIN: a case study in European academic co-operation
Authors: Dowrick C. , Vázquez-Barquero J.L. , Wilkinson G. , Wilkinson C. , Lehtinen V. , Dalgard O.S. , Casey P. ,   The ODIN Group
Published: July 2002

SummaryThe European Commission is an increasingly important source of funding for international research projects and is due to announce its Framework 5 program early in 1999. The Outcomes of Depression International Network (ODIN), funded from the current EC Biomed 2 program, is a case study in European academic co-operation. Its organization has three key elements. First, engaging the principal investigators: this has involved identifying potential partners, ensuring reciprocity of interests, effective co-ordination, `dividing the spoils' in advance, and setting up good personal and electronic communication systems. Second, an esprit de corps has been created amongst the researchers, maintaining contact and consistency, and promoting higher degrees. Third, ongoing problems including difficulties in negotiations with the EC, divergence of detailed study methods, and isolation and demoralization amongst researchers, have been addressed. ODIN may provide a useful model for researchers wishing to set up international collaborative groups.
Skeletal muscle characteristics, muscle strength and thigh muscle area in patients before and after cardiac transplantation
Authors: Schaufelberger Maria , Eriksson Bengt O. , Lönn Lars , Rundqvist Bengt , Sunnerhagen Katharina Stibrant , Swedberg Karl 
Published: July 2002

AbstractBackground:Patients with chronic heart failure demonstrate several skeletal muscle abnormalities. The underlying mechanisms are unclear. After cardiac transplantation, cardiac function is restored, but exercise capacity is still impaired.Aim:To evaluate the influence of cardiac transplantation on skeletal muscle fibre composition, fibre area and capillarization as well as muscle enzymes, lactate, thigh muscle area and strength.Methods:Ten patients were longitudinally investigated before, 1–3 and 6–9 months after transplantation. Ten healthy individuals served as controls. A biopsy from the lateral vastus muscle was obtained and the thigh muscle area was measured with computed tomography. Muscle strength in the knee extensors and exercise capacity were also evaluated.Results:Muscle lactate was elevated in patients vs. controls (3.6±3.0 vs. 1.5±0.7 mmol/kg wet wt., P = 0.037), and decreased to normal (1.4±0.3 mmol/kg wet wt., P = 0.038) after transplantation. Citrate synthase activity was decreased in patients (5.6±1.5 μmol/g wet wt./min) vs. controls (8.1±1.6 μmol/g wet wt./min, P = 0.0018), and did not change post transplantation. Patients had decreased number of capillaries in contact with each fibre vs. controls (2.6±0.5 vs. 3.5±1.0, P = 0.039) which persisted post transplantation. Exercise capacity increased after transplantation (74±22 vs. 118±26 W, P = 0.0002), whereas muscle strength did not improve significantly.Conclusion:The persisting intrinsic abnormalities in skeletal muscle after cardiac transplantation may contribute to the impaired exercise capacity observed in cardiac transplant recipients.
Worsening of heart failure during hospital course of an unselected cohort of 2507 patients with myocardial infarction is a factor of poor prognosis: the PRIMA study
Authors: de Gevigney Guy , Ecochard René , Rabilloud Muriel , Gaillard Sandrine , Cheneau Edouard , Ducreux Corinne , Cao Danièle , Milon Hugues , Delahaye François ,   PRIMA group
Published: July 2002

AbstractWorsening of heart failure in patients with myocardial infarction is seldom studied, elderly patients often are not included, and multivariate analysis is uncommon. The prospective PRIMA study (Prise en charge de l'Infarctus du Myocarde Aigu; management of acute myocardial infarction) sought to determine the incidence of worsening heart failure, its risk factors, and its prognostic importance in patients with myocardial infarction, regardless of age and hospital facilities, in the ‘real world’ in a region in France, using multivariate analysis. Data were prospectively collected in all patients with myocardial infarction admitted in all hospitals in three departments in the Rhône–Alpes region in France between 1 September 1993 and 31 January 1995. Among the 2507 patients included, 33% were in Killip classes II–IV at admission. After exclusion of patients with admission Killip class IV, 416 patients (17% of the cohort, 24% of women and 14% of men) had worsening of Killip class during the first 5 days. In‐hospital mortality (overall, 14%) increased dramatically with Killip class at admission (9% in class I, 62% in class IV) and with worsening of Killip class during the first 5 days (36.5 vs. 8.5% if no worsening). In multivariate analysis, older age, diabetes mellitus and anterior Q‐wave myocardial infarction were significant predictors of Killip class at admission and of its worsening; Killip class > I at admission was a significant predictor of Killip‐class worsening. The significant predictors of in‐hospital mortality were older age, Killip class III at admission and worsening of Killip class during the first 5 days. This large, unselected cohort revealed that, among patients with myocardial infarction, heart failure and its worsening are frequent, especially in the elderly, and dramatically worsen the in‐hospital mortality.
Indicators of myocardial dysfunction and quality of life, one year after acute infarction
Authors: Ecochard René , Colin Cyrille , Rabilloud Muriel , de Gevigney Guy , Cao Danièle , Ducreux Corinne , Delahaye François ,   PRIMA group
Published: July 2002

AbstractBackground:There remains controversy concerning the association between myocardial dysfunction diagnosed soon after acute myocardial infarction (AMI), and subsequent quality of life.Aims:We searched for a correlation between criteria of myocardial dysfunction assessed within the first month after AMI, and quality of life perceived 1 year later.Methods:Six hundred and seventy‐one patients were followed up and quality of life was assessed using the Nottingham Health Profile. Spearman correlation was used for univariate analyses. A logistic regression identified independent predictors of impaired quality of life.Results:Patients perceiving inferior quality of life were 61% for energy, 61% for sleep, 49% for physical mobility, 49% for pain, 63% for emotional reactions, and 28% for social isolation. Impaired quality of life was not associated with the initial Killip class. A low ejection fraction was associated with impaired physical mobility (OR ‐ 1.21, 95% CI ‐ 1.05–1.39). Presence of abnormally contracting myocardial segments was associated with impaired mobility (1.40, 1.09–1.80) and with increased pain (1.30, 1.02–1.66). The presence of diseased coronary vessels was associated with pain (1.25, 1.06–1.46).Conclusion:Myocardial dysfunction was generally associated with impaired quality of life. This has to be considered when assessing improvement of quality of life after medical or surgical treatment of AMI.
Productivity and persistence of Kura clover and white clover mixtures with grasses
Authors: Seguin Philippe , Pomerleau‐Lacasse Florence , Drapeau Raynald , Lajeunesse Julie , St‐Pierre‐Lepage Sandrine 
Published: April 2020

AbstractThere is a lack of persistent forage legumes for permanent pastures in eastern Canada. Kura clover (Trifolium ambiguum M. Bieb.; KC) is a long‐lived species, with demonstrated potential in various regions, however, there is a lack of information on its performance in mixtures with grasses and no comparisons with white clover (Trifolium repens L.; WC), the main legume species recommended for pastures in eastern Canada. Objectives were to evaluate the potential of KC when grown in mixtures with grasses and compare its performance with WC based‐mixtures and N‐fertilized grass monocultures. Twenty treatments that included KC, WC, and six perennial grasses species (Kentucky bluegrass [Poa pratensis L.; KB], meadow bromegrass [Bromus biebersteinii Roem. & Schult., MB], orchardgrass [Dactylis glomerata L., OR], smooth bromegrass [Bromus inermis L.; SB], tall fescue [Schedonorus arundinaceus (Schreb.) Dumort.; TF], and timothy [Phleum pratense L.; TI]) seeded alone and in binary mixtures were seeded in 2 yr at two sites and monitored for up to four production years. During the first production year, WC‐based mixtures yields were overall greater than those of KC‐based mixtures, while in the second production year and onwards, KC treatments had similar or greater yields than WC, illustrating the greater persistence of KC. Adding KC to grasses also increased total forage yields by 13% on average compared to N‐fertilized solo‐seeded grasses. The performance of specific KC–grass mixtures was variable across sites‐years with no specific mixture being consistently more productive. Kura clover is adapted to contrasting environments of Québec and appears to be a suitable alternative to WC.