bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single-particle perovskite lasers: from material properties to cavity design
Authors: Polushkin Artem S. , Tiguntseva Ekaterina Y. , Pushkarev Anatoly P. , Makarov Sergey V. 
Published: February 2020

Abstract
Last decade, halide perovskites demonstrate high potential for efficient, tunable, and cheap photonic sources. Recently, single-particle perovskite lasers of various compositions and shapes with all dimensions close or smaller than the emitted wavelengths were demonstrated experimentally in a broad range of temperatures. In this review, we aim to cover not only the recent progress in the single-particle perovskite lasers but also provide a comprehensive analysis on strategies to achieve the most compact perovskite lasers with the best working parameters.
Frequency-multiplexed pure-phase microwave meta-holograms using bi-spectral 2-bit coding metasurfaces
Authors: Iqbal Shahid , Rajabalipanah Hamid , Zhang Lei , Qiang Xiao , Abdolali Ali , Cui Tie Jun 
Published: February 2020

Abstract
In this paper, a dual-band reflective meta-hologram is designed providing two distinct information channels whose field intensity distributions can be independently manipulated at the same time. The proposed pure-phase meta-hologram is composed of several frequency-dispersive coding meta-atoms possessing each of 2-bit digital statuses of “00”, “01”, “10”, and “11” at either the lower (X-band) or the higher (Ku-band) frequency band. Relying on the weighted Gerchberg-Saxton phase retrieval algorithm, different illustrative examples have been provided to theoretically inspect the dual-band performance of our coding meta-hologram. Numerical simulations validate the proposed frequency multiplexing meta-holography with the ability to project two different high-quality images with low cross-talk on two X-band and Ku-band near-field channels located at distinct pre-determined distances from the metasurface plane. As proof of concept, two meta-hologram samples are fabricated, and the experimental results corroborate well the numerical simulations and theoretical predictions. The designed meta-hologram features all fascinating advantages of the coding metasurfaces while its performance overcomes that of previous studies due to providing two information channels rather than the conventional single-channel holography. The frequency multiplexing acquired by the proposed bi-spectral coding meta-hologram may provide great opportunities in a variety of applications, such as data storage and information processing.
All-optical modulation with 2D layered materials: status and prospects
Authors: Chen Haitao , Wang Cong , Ouyang Hao , Song Yufeng , Jiang Tian 
Published: February 2020

Abstract
Optical modulation technique plays a crucial role in photonics technologies, and there is an ever-increasing demand for broadband and ultrafast optical modulation in the era of artificial intelligence. All-optical modulation is known to be able to operate in an ultrafast way and has a broadband response, showing great potential in applications for ultrafast information processing and photonic computing. Two-dimensional (2D) materials with exotic optoelectronic properties bring tremendous new opportunities for all-optical modulators with excellent performance, which have attracted lots of attention recently. In this review, we cover the state-of-art all-optical modulation based on 2D materials, including graphene, transitional metal dichalcogenides, phosphorus, and other novel 2D materials. We present the operations mechanism of different types of all-optical modulators with various configurations, such as fiber-integrated and free-space ones. We also discuss the challenges and opportunities faced by all-optical modulation, as well as offer some future perspectives for the development of all-optical modulation based on 2D materials.
Solar-blind deep-ultraviolet photodetectors based on solution-synthesized quasi-2D Te nanosheets
Authors: Cao Rui , Zhang Ye , Wang Huide , Zeng Yonghong , Zhao Jinlai , Zhang Liyuan , Li Jianqing , Meng Fanxu , Shi Zhe , Fan Dianyuan , Guo Zhinan 
Published: February 2020

Abstract
Solar-blind deep ultraviolet (DUV) photodetectors with high responsivity (R) and fast response speed are crucial for practical applications in astrophysical analysis, environmental pollution monitoring, and communication. Recently, 2D tellurium has emerged as a potential optoelectronic material because of its excellent photoelectric properties. In this study, solar-blind DUV photodetectors are demonstrated based on solution-synthesized and air-stable quasi-2D Te nanosheets (Te NSs). An R of 6.5 × 104 A/W at 261 nm and an external quantum efficiency (EQE) of higher than 2.26 × 106% were obtained, which are highest among most other 2D material-based solar-blind DUV photodetectors. Moreover, the photoelectric performance of the quasi-2D Te-based photodetector exhibited good stability even after ambient exposure for 90 days without any encapsulation. These results indicate that quasi-2D Te NSs provide a viable approach for developing solar-blind DUV photodetectors with ultrahigh R and EQE.
Into the Grey Zone, Or: How to Track Fading Multiculturalism in Southeastern Europe
Authors: Dippel Anne , Bopp-Filimonov Valeska 
Published: February 2020

AbstractThe exhibition ‘“We Live Word to Word.” Banat – Transylvania – Bukovina. Ethno graffiti of Southeastern Europe’ resulted from an interdisciplinary project seminar at the Friedrich Schiller University Jena, based on a team ethnographic journey to Romania and Ukraine. Participants in the seminar, initiated in 2018, investigated how communities and togetherness have been constructed in multiethnic societies. The purpose was to find out what has remained of the region’s multicultural nature after the political changes of 1989. The team made their own observations, recorded interviews, and took notes, the resulting fragments of cultural diversity being later pieced together in the exhibition. Some contributions were colourful—even garish—while others were tender and withdrawn. Combined and linked, the final result seemed like a fleeting picture such as might have been sprayed from the aerosols of a street-artist—a sort of ‘ethnograffiti’. In this article, the authors reflect on how the exhibition was put together.
Effects of topiramate on adipocyte differentiation and gene expression of certain carbonic anhydrase isoenzymes
Authors: Sümer Ayşegül , Keha Eşref Edip , Menteşe Ahmet , Alver Ahmet 
Published: February 2020

Abstract

Background
Topiramate, an antiepileptic drug, besides its known effects in neurons, is a carbonic anhydrase inhibitor and causes weight loss in treated subjects, but, the mechanisms of weight loss effect have not been yet identified..

Objective
In this study, effects of topiramate on 3T3-L1 adipocyte differentiation and expressions of carbonic anhydrase I, II, III, VA, VB were investigated to determine possible roles of carbonic anhydrase isoenzymes and adipocytes in weight loss effect of topiramate.

Material and methods
Adipocyte differentiation was detected by Oil Red O staining. Carbonic anhydrase I, II, III, VA, VB expressions were determined by Real-Time PCR method.

Results
It was found that topiramate induced adipogenesis at all concentrations (p < 0.0001). CA expressions increased significantly with adipogenesis (p = 0.0001). Topiramate stimulated adipogenesis in 3T3-L1 cells and reduced CA II, VA and VB and, an increased CA III expression was observed at low concentrations. CA II, VA and, VB expressions were found increased and CA III expression decreased at high topiramate concentrations.

Conclusion
It was concluded that changes in CA III expression were consistent with its reduction in obesity, alterations of CA II, VA and VB expressions could be attributed to compensation mechanism of cells.
A binuclear Cd(II) complex containing bridging pyrimidine-based ligands
Authors: Hosseini Samireh , Mardani Zahra , Moeini Keyvan , Carpenter-Warren Cameron , Slawin Alexandra M.Z. , Woollins J. Derek 
Published: February 2020

AbstractIn this work, a pyrimidine-based ligand,N′-(amino(pyrimidin-2-yl)methylene)pyrimidine-2-carbohydrazonamide hydrate (APPH · H2O), and its binuclear complex of cadmium, [Cd(μ-APPH)Br]2,1, were prepared and identified by elemental analysis, FT-IR,1H NMR spectroscopy as well as single-crystal X-ray diffraction. X-ray structure analysis of1revealed octahedrally coordinated cadmium centers with a CdN4Br2environment containing two bridging APPH ligands; each APPH ligand acts as an N4-donor (N2-donor toward each cadmium atom) and forms two five-membered chelate rings that are approximately perpendicular to each other. In the network of1, the N–H · · · Br hydrogen bonds form motifs such asR22(12, 14), R66(24, 26, …, 46).${\rm{R}}_{\rm{2}}^{\rm{2}}(12,{\rm{ }}14),{\rm{ R}}_{\rm{6}}^{\rm{6}}(24,{\rm{ }}26,{\rm{ }} \ldots ,{\rm{ }}46).$The crystal network is further stabilized by π-π stacking interactions between pyrimidine rings. The optimized structures of the ligand and complex were investigated along with their charge distribution patterns by density functional theory and natural bond orbital analysis, respectively.
Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction
Authors: Perfitt Tyler L. , Wang Xiaohan , Dickerson Matthew T. , Stephenson Jason R. , Nakagawa Terunaga , Jacobson David A. , Colbran Roger J. 
Published: February 2020

The activation of neuronal plasma membrane Ca2+channels stimulates many intracellular responses. Scaffolding proteins can preferentially couple specific Ca2+channels to distinct downstream outputs, such as increased gene expression, but the molecular mechanisms that underlie the exquisite specificity of these signaling pathways are incompletely understood. Here, we show that complexes containing CaMKII and Shank3, a postsynaptic scaffolding protein known to interact with L-type calcium channels (LTCCs), can be specifically coimmunoprecipitated from mouse forebrain extracts. Activated purified CaMKIIα also directly binds Shank3 between residues 829 and 1130. Mutation of Shank3 residues949Arg-Arg-Lys951to three alanines disrupts CaMKII bindingin vitroand CaMKII association with Shank3 in heterologous cells. Our shRNA/rescue studies revealed that Shank3 binding to both CaMKII and LTCCs is important for increased phosphorylation of the nuclear CREB transcription factor and expression of c-Fos induced by depolarization of cultured hippocampal neurons. Thus, this novel CaMKII-Shank3 interaction is essential for the initiation of a specific long-range signal from LTCCs in the plasma membrane to the nucleus that is required for activity-dependent changes in neuronal gene expression during learning and memory.SIGNIFICANCE STATEMENTPrecise neuronal expression of genes is essential for normal brain function. Proteins involved in signaling pathways that underlie activity-dependent gene expression, such as CaMKII, Shank3, and L-type calcium channels, are often mutated in multiple neuropsychiatric disorders. Shank3 and CaMKII were previously shown to bind L-type calcium channels, and we show here that Shank3 also binds to CaMKII. Our data show that each of these interactions is required for depolarization-induced phosphorylation of the CREB nuclear transcription factor, which stimulates the expression of c-Fos, a neuronal immediate early gene with key roles in synaptic plasticity, brain development, and behavior.
Some Tasting Notes on Year-Old Sushi: Funazushi, Japan's Most Ancient and Potentially Its Most Up-to-Date Sushi
Authors: Rath Eric C. 
Published: February 2020

Funazushi, a fermented food made with crucian carp, is often described as Japan's most ancient form of sushi. This article evaluates these historical claims and offers some tasting notes, exploring traditional versions of the dish and new interpretations that offer a possible future for sushi.
I could never write a global history of sushi without having eaten what has been called the most “ancient form” of sushi, the funazushi found in Shiga Prefecture (Hosking 1996: 43). So on a recent trip to Japan I set aside two days to try to eat as much funazushi as possible. This proved to be challenging for many reasons, not the least of which was the taste of funazushi, which many people find disagreeable. What I learned from the experience was less about sushi's past than a possibility for sushi's future.
Properties of integrals which have the type of derivatives of volume potentials for one ultraparabolic arbitrary order equation
Authors: Dron' V.S. , Ivasyshen S.D. , Medyns'kyi I.P. 
Published: February 2020

In weighted Hölder spaces it is studied the smoothness of integrals, which have the structure and properties of derivatives of volume potentials which generated by fundamental solutions of the Cauchy problem for one ultraparabolic arbitrary order equation of the Kolmogorov type. The coefficients in this equation depend only on the time variable. Special distances and norms are used for constructing of the weighted Hölder spaces.
The results of the paper can be used for establishing of the correct solvability of the Cauchy problem and estimates of solutions of the given non-homogeneous equation in corresponding weighted Hölder spaces.
Non-linear Mixed Models in a Dose Response Modelling
Authors: Wijaya Madona Yunita 
Published: February 2020

AbstractStudy designs in which an outcome is measured more than once from time to time result in longitudinal data. Most of the methodological works have been done in the setting of linear and generalized linear models, where some amount of linearity is retained. However, this still be considered a limiting factor and non-linear models is another option offering its flexibility. Non-linear model involves complexity of non-linear dependence on parameters than that in the generalized linear class. It has been utilized in many situations such as modeling of growth curves and dose-response modeling. The latter modeling will be the main interest in this study to construct a dose-response relationship, as a function of time to IBD (inflammatory bowel disease) dataset. The dataset comes from a clinical trial with 291 subjects measured during a 7 week period. Both linear and non-linear models are considered. A dose time response model with generalized diffusion function is utilized for the non-linear models. The fit of non-linear models are found to be more flexible than linear models hence able to capture more variability present in the data.Keywords: IBD; longitudinal; linear mixed model; non-linear mixed model. AbstrakDesain studi dimana hasil diukur berulang kali dari waktu ke waktu menghasilkan data longitudinal. Sebagian besar metodologi yang digunakan untuk menganalisis data longitudinal adalah model linear dan model linear umum (generalized linear model) dimana sejumlah linearitas tertentu dipertahankan. Asumsi linearitas ini masih dipandang memiliki keterbatasan dan model non-linear adalah pilihan metode lainnya yang menawarkan fleksibilitas. Model non-linear telah digunakan di berbagai macam situasi seperti model kurva pertumbuhan , model farmakokinetika, dan farmakodinamika, dan model respon-dosis. Model respon-dosis akan menjadi fokus dalam penelitian ini untuk membangun hubungan dosis-respon sebagai fungsi waktu dari data IBD dengan menggunakan model linear dan non-linear. Hasil penelitian menunjukan bahwa model non-linear lebih fleksibel daripada model linear sehingga mampu menangkap lebih banyak variabilitas yang ada di dalam data.Keywords: IBD; longitudinal; model linear; model non-linear.
The effect of altitude and progressive exercise activity on the profile of testosterone changes and Some of immunity markers in active student basketball team
Authors: Rahmani Ghobadi Maria , Taghavi Dehaghani Sepehr , Nazari Mohammadreza 
Published: February 2020

Background and Study Aim. Training activities and altitude cause some of changes in the physiological adaptations and also athletic functionality. The purpose of this study was the effect of altitude and progressive exercise activity on the profile of testosterone changes and Some of immunity markers in active student basketball team.
Material and Methods. As to subjects this survey, 36 active male students with an average age of (19.5± 0.83) were selected from 36 athletes with a maximum rate of oxygen uptake of about (VO2max=58.66± 2.9). The subjects, who were tested in the sea level f and post IAE (8 of periodical ascending to the height of 2800 meters for 3 days), were then asked on cycle ergometer (starting with 100 watts, increasing 25 watts every 3 minutes, with the work-to-rest ratio of 3 to 1) to exhaustion. The initial blood sampling of the subjects was done 72 hours before the main test to determine the similar conditions of the subjects, and to measure the initial level of Testosterone hormone, lymphocytes and neutrophiles, in the sea level. Also, the blood sampling of both after and before the progressive exercise activity and the IAE stage were done. The serumal concentration of testosterone was measured via Elisa method and the amounts of lymphocytes and neutrophiles were determined using Cell-Counter set. For statistical analysis, using the tests of Kolmogorov and Smirnov, repeated measurements were done in the level of (p≤0.05). The complete process of analyzing the result was done through the software SPSS22.
Results. The outcomes of the present survey show the amount of lymphocytes and neutrophiles after a session of progressive exercise activity have had a meaningful increase (p<0.05). But, the increase rate of testosterone was not meaningful difference (p>0.05). Testosterone, lymphocytes and neutrophiles showed a meaningful increase after progressive exercise activity in IAE conditions (p<0.05). Also, the amounts of Testosterone, lymphocytes and neutrophiles, before IAE has not shown a meaningful rise, when compared to sea level conditions (p>0.05).
Conclusions. It seems that, even though these changes were not meaningful, they were effective in reducing both the functionality of the subjects and the exhaustion duration. Therefore, it seems that repeated IAE sessions over three days can provide physiological adaptations to height and decrease Prevent performance.
External Validation of a Venous Thromboembolic Risk Score for Cancer Outpatients with Solid Tumors: The COMPASS-CAT Venous Thromboembolism Risk Assessment Model
Authors: Spyropoulos Alex C. , Eldredge Joanna B. , Anand Lalitha N. , Zhang Meng , Qiu Michael , Nourabadi Soheila , Rosenberg David J. 
Published: February 2020

Abstract

Background
Current risk assessment models (RAMs) for prediction of venous thromboembolism (VTE) risk in the outpatient cancer population have shown poor predictive value in many of the most common cancers. The Comparison of Methods for Thromboembolic Risk Assessment with Clinical Perceptions and AwareneSS in Real Life Patients-Cancer Associated Thrombosis (COMPASS-CAT) RAM was derived in this patient population and predicted patients at high risk for VTE even after initiation of chemotherapy. We sought to externally validate this RAM.

Materials and Methods
Patients aged ≥18 years who presented to a tertiary care center between January 1, 2014, and December 31, 2016, with invasive breast, ovarian, lung, or colorectal cancers were included. The COMPASS-CAT RAM was applied using our health system's tumor registry and variables that were identified by International Statistical Classification of Diseases and Related Health Problems-9 and -10 codes of the electronic health record and independent chart review. The primary endpoint at 6-month study follow-up was documented VTE.

Results
A total of 3,814 patients were included. Documented VTE at 6-month follow-up occurred in 5.85% of patients. Patients stratified into low/intermediate- and high-risk groups had VTE rates of 2.27% and 6.31%, respectively. The sensitivity, specificity, and negative and positive predictive value of the RAM were 95%, 12%, 97.73%, and 6.31%, respectively. Diagnostic accuracy via receiver operating characteristic curve was calculated at 0.62 of the area under the curve.

Conclusion
In this large retrospective external validation study of the COMPASS-CAT RAM for VTE in patients with cancer undergoing active treatment, model discrimination was moderate and calibration was poor. The model had good negative predictive value. Further prospective validation studies—especially within 6 months of cancer diagnosis—are needed before the model can be implemented into routine clinical practice for primary thromboprophylaxis of high-VTE-risk patients with cancer with solid tumors.

Implications for Practice
This study provides further guidance for researchers and clinicians in determining clinical and laboratory risk factors associated with development of venous thromboembolism among the ambulatory population of patients being treated for lung, breast, colorectal, or ovarian cancer. It validates the COMPASS-CAT risk model that was developed in this cancer population and suggests that further prospective validation of the model, with more focus on patients within 6 months of their index cancer diagnosis, would likely enhance the accuracy and usefulness of this model as a clinical prediction tool.