bluuebunny/crossref_metadata_2025_split huggingface dataset:
An analysis of users’ preferences on learning management systems: a case on German versus Spanish students
Authors: Tinmaz Hasan , Lee Jin Hwa 
Published: October 2020

AbstractThe recent advancements in information and communication technologies have altered instructional contexts and re-shaped them into smart learning environments. One of the most common practices of these environments are learning management systems (LMS) where the learners and instructors utilize a software platform to fulfill, support and manage instructional activities around predefined objectives. Successful implementations of LMS have brought a variety on its usage from different cultures, genders, age groups or schooling levels. Hence, this study focuses on understanding the role of culture on LMS design, in along with the effects of gender, age and school year variables. The study participants were German (n = 83) and Spanish (n = 83) university students attending a fully online course offered by a South Korean university. At the end of the course, the students were asked to fulfill a survey on effective LMS design by pointing which features of LMS were more important for them. The survey included twenty questions on four major design factors; content management (six items), ease of use (five items), communication within LMS (four item) and screen design (five items). The dataset was analyzed by non-parametric statistical techniques around four variables on four dimensions (and their related survey questions). The most important result was insufficiency of one unique LMS design for all students which demonstrates the necessity of student demographics tailored smart systems. Additionally, age and gender variables were not making significant differences on LMS design as much as culture and school year variables. The study also revealed that while German students would appreciate goal-oriented individual learning, Spanish students would value process-oriented group learning with active communication. Furthermore, many features of LMS were highly valued by the freshman students more than other levels. The paper discusses these variables with possible explanations from the literature and depicts implementations for future design practices.
Method of Ga removal from a specimen on a microelectromechanical system-based chip for in-situ transmission electron microscopy
Authors: Kwon Yena , An Byeong-Seon , Shin Yeon-Ju , Yang Cheol-Woong 
Published: October 2020

AbstractIn-situ transmission electron microscopy (TEM) holders that employ a chip-type specimen stage have been widely utilized in recent years. The specimen on the microelectromechanical system (MEMS)-based chip is commonly prepared by focused ion beam (FIB) milling and ex-situ lift-out (EXLO). However, the FIB-milled thin-foil specimens are inevitably contaminated with Ga+ ions. When these specimens are heated for real time observation, the Ga+ ions influence the reaction or aggregate in the protection layer. An effective method of removing the Ga residue by Ar+ ion milling within FIB system was explored in this study. However, the Ga residue remained in the thin-foil specimen that was extracted by EXLO from the trench after the conduct of Ar+ ion milling. To address this drawback, the thin-foil specimen was attached to an FIB lift-out grid, subjected to Ar+ ion milling, and subsequently transferred to an MEMS-based chip by EXLO. The removal of the Ga residue was confirmed by energy dispersive spectroscopy.
Mimetic finite-difference coupled-domain solver for anisotropic media
Authors: Sethi Harpreet , Shragge Jeffrey , Tsvankin Ilya 
Published: October 2020

Accurately modeling full-wavefield solutions at and near the seafloor is challenging for conventional single-domain elastic finite-difference (FD) methods. Because they treat the fluid layer as a solid with zero shear-wave velocity, the energy partitioning for body and surface waves at the seafloor is distorted. This results in incorrect fluid/solid boundary conditions, which has significant implications for imaging and inversion applications that use amplitude information for model building. To address these issues, here we use mimetic FD (MFD) operators to develop and test a numerical approach for accurately implementing the boundary conditions at a fluid/solid interface. Instead of employing a single “global” model domain, we partition the full grid into two subdomains that represent the acoustic and elastic (possibly anisotropic) media. A novel split-node approach based on one-sided MFD operators is introduced to distribute grid points at the fluid/solid interface and satisfy the wave equation and the boundary conditions. Numerical examples demonstrate that such MFD operators achieve stable implementation of the boundary conditions with the same (fourth) order of spatial accuracy as that inside the split-domain interiors. We compare the wavefields produced by the MFD scheme with those from a more computationally expensive spectral-element method to validate our algorithm. The modeling results help analyze the events associated with the fluid/solid (seafloor) interface and provide valuable insights into the horizontal displacement or velocity components (e.g., recorded in ocean-bottom-node data sets). The developed MFD approach can be efficiently used in elastic anisotropic imaging and inversion applications involving ocean-bottom seismic data.
Cross-sectional study of Facebook addiction in a sample of Nepalese population
Authors: Atreya Alok , Nepal Samata , Thapa Prakash 
Published: October 2020

Background: Facebook addiction is said to occur when an individual spends an excessive amount of time on Facebook, disrupting one’s daily activities and social life. The present study aimed to find out the level of Facebook addiction in the Nepalese context and briefly discuss the issues associated with its unintended use. Methods: A descriptive cross-sectional study was conducted in the Department of Forensic Medicine of Lumbini Medical College. The study instrument was the Bergen Facebook Addiction Scale typed into a Google Form and sent randomly to Facebook contacts of the authors. The responses were downloaded in a Microsoft Excel spreadsheet and analyzed using Statistical Package for Social Sciences version 16. Results: The study consisted of 103 Nepalese participants, of which 54 (52.42%) were males and 49 females (47.58%). There were 11 participants (10.68%) who had more than one Facebook account. When different approaches were applied it was observed that 8.73% (n=9) to 39.80% (n=41) were addicted to Facebook. Conclusion: When used properly Facebook has its own advantages. Excessive use is linked with health hazards including addiction and dependency. Students who engage more on Facebook may have less time studying, leading to poor academic performance. People need to be made aware of the issues associated with the misuse of Facebook.
Beyond the dermis—high-risk invasive squamous cell carcinoma: a retrospective review
Authors: Sood Anshum , Bivona Louis , Mahkzoumi Zaineb , Hausner Petr , Miller Kenneth , Regine William F , Snider James , Ng Vincent Y 
Published: October 2020

Objective: Most cutaneous squamous cell carcinomas (cSCC) are low risk and can be treated with simple excision or ablation. High-risk cSCC require invasive treatment, including radical surgery. We present our experience in treating invasive cSCC of the pelvis and extremities. Method: A retrospective review of the data of patients with invasive cSCC, indicated for surgery between 2014 and 2018, from a single institution was carried out. Results: A total of 19 patients (nine men, 10 women) were included in the study. Mean age was 62 years; mean tumour size was 8.6cm). Of the 19 patients, five patients with paraplegia with cSCC arising from hard-to-heal ulcers died of infection or bleeding after surgery or systemic therapy. Also, nine patients with localised cSCC underwent margin-negative resection with or without radiation; one patient experienced disease relapse. Of the participants, two patients with previous transplants and multifocal aggressive cSCC underwent numerous resections but succumbed to disease, and two patients who presented with locally recurrent disease after previous positive margin resection and radiation underwent re-resection but developed recurrent disease. Conclusions: Prognosis for invasive cSCC largely depends on clinical setting. Tumours arising from ulcers in patients with paraplegia have a poor prognosis regardless of treatment. Invasive cSCC in transplant patients are often multifocal and often recur. Debulking procedures are associated with local recurrence despite radiation. Patients presenting with localised disease have a favourable prognosis with wide resection, flap coverage and adjuvant therapy.
Der Einsatz von Servicerobotern bei Epidemien und Pandemien
Authors: Bendel Oliver 
Published: October 2020

ZusammenfassungSeit jeher werden Roboter eingesetzt, um gefährliche oder für uns nicht bewältigbare Aufgaben zu erledigen. Sie entschärfen Bomben, transportieren Gefahrenstoffe und arbeiten sich in für uns nicht erreichbare Gebiete vor. Die COVID-19-Pandemie hat gezeigt, dass auch Serviceroboter, die eigentlich nicht für Sonderfälle vorgesehen sind, hilfreiche Dienste bei der Versorgung von Isolierten und bei der Eindämmung von Krankheiten leisten können. Der vorliegende Beitrag stellt vier Typen von Servicerobotern vor. Dann gibt er Beispiele für die Roboternutzung während der Coronakrise im Jahre 2020. Schließlich wird der Frage nachgegangen, in welchem Umfang und in welcher Weise die Robotertypen zusammenarbeiten können und ob man manche von ihnen zu Generalisten weiterentwickeln kann. Zudem werden Geschäftsmodelle und Betriebsmöglichkeiten thematisiert. Der Beitrag zeigt, dass Kohorten von Robotern in Zukunft lebenswichtig sein könnten.
Wissens- und lernorientierte Instandhaltung unter dem Aspekt zunehmender Digitalisierung
Authors: Huber Cornelia , Passath Theresa , Biedermann Hubert 
Published: October 2020

ZusammenfassungDie Digitalisierung bietet Industrieunternehmen eine Vielzahl von Möglichkeiten und Lösungen (z. B. Big Data Analytics, Cloud-Computing, Internet of Things), die mit zunehmenden Anforderungen an das Wissensmanagement verbunden sind. Ein angepasstes Assetmanagement zur Sicherstellung von Markterfolgsfaktoren sind für die Smart Factory unerlässlich. Ein ganzheitliches wertschöpfungsorientiertes Managementkonzept bietet die Lean Smart Maintenance Philosophie, das den geänderten Umfeldbedingungen Rechnung tragend, eine dynamisch anpassbare Instandhaltungsstrategie ermöglicht. Insbesondere die Ressource Wissen gewinnt in Anbetracht einer ständig steigenden Anlagenkomplexität in Form der wissen- und lernorientierten Instandhaltung an Bedeutung, damit zukünftig der Einsatz neuer Technologien nachhaltig wirtschaftlich ist. In diesem Zusammenhang wird nachstehend eine praxisnahe Vorgehensmethodik präsentiert, die die Externalisierung impliziten Wissens durch die Kombination der Wissensbausteine nach Probst mit dem DMAIC-Zyklus unterstützt. Die Digitalisierung induziert geänderte Anforderungen an die Mitarbeiter und Mitarbeiterinnen; geeignete Qualifizierungsmaßnahmen sollten für die bestmögliche Weiterentwicklung der Humanressourcen frühzeitig erkannt und implementiert werden.
Service evaluation and retrospective audit of electronic HEEADSSS (e-HEEADSSS) screening device in paediatric inpatient service in Western Australia
Authors: Saw Chia , Smit Alide , Silva Desiree , Bulsara Max K. , Nguyen Edward Tam Thuong Tran 
Published: October 2020

Abstract

Objectives
The top causes of adolescents’ mortality in Australia and worldwide are mostly preventable and many stem from psychosocial difficulties. The HEEADSSS screening is a widely accepted screening tool in assessing young people’s psychosocial wellbeing. This retrospective audit was done to evaluate the service implementation of an electronic-HEEADSSS (e-HEEADSSS) screening system in a regional hospital’s paediatric in-patient setting in Western Australia. The aim is to examine and compare the uptake rate of conventional HEEADSSS screening in 2018 and e-HEEADSSS screening in 2019, and to examine the relevant outcome and disclosure rate by the young person.

Methods
This retrospective audit (pre-post cross sectional study) is reported using the STROBE guideline. It was done over two different time frames: Pre e-HEEADSSS implementation (September–December 2018) and Post e-HEEADSSS implementation (September–December 2019). Inclusion criteria includes: All paediatric inpatients aged 12–16 years old. Exclusion criteria includes: Admission under other disciplines or clinically unstable/unsuitable patients. The uptake rate of conventional-HEEADSSS (2018) in comparison to e-HEEADSSS screening (2019) was examined. Other relevant data was extracted and analysed.

Results
The sample size pre-implementation was 26 while post-implementation was 24. The uptake rate increased from 12% (conventional-HEEADSSS) to 54% (e-HEEADSSS), a 450% increment with the e-HEEADSSS system implementation (Fisher Exact Test, p=0.005). More than half of young people who completed their e-HEEADSSS screening had concerns/flags which required management by the clinicians. 86% of patients in the e-HEEADSSS group with concerns/flags were acted appropriately by the treating clinicians prior to discharge. The overall disclosure rate of e-HEEADSSS was 93% with highest disclosure rate for ‘Drugs’ domain.

Conclusions
There is significant increase in uptake rate with high disclosure rate using e-HEEADSSS screening device when compared to conventional HEEADSSS screening in the paediatric in-patient setting. The e-HEEADSSS is a better screening tool for in-patient setting and should be implemented widely.
„Odi profanum vulgus et arceo“. Zwei lateinische Oden des Schülers Nietzsche
Authors: Wollek Christian 
Published: October 2020

AbstractThe detailed interpretation and translation of Nietzsche’s early Latin odes clearly show that Horace’s lyric poetry has an exemplary function for the development of Nietzsche’s own poetic language. Even in his later works, such asTwilight of the Idolsand theDionysos-Dithyrambs, Nietzsche’s poetic style and rhetorical strategies remain indebted to his early attempts to emulate classical Latin poetry when he was a pupil at the Pforta boarding school.
Some Recent Work on Nietzsche’s Ethical Thought
Authors: Elgat Guy 
Published: October 2020

Abstract
An important question in Nietzsche studies is whether Nietzsche has an ethics to offer his readers; whether, that is, he has a concept of the good, or the just, or the virtuous that can serve as some sort of an ethical guide. An additional, methodological question is whether, in search of an answer, one should focus on a specific period in his thinking, study the evolution of his thought, or attempt to extract an over-arching view that draws on texts from different stages of his thinking. The three works reviewed concern themselves with Nietzsche’s ethics by each adopting one of these three approaches, supplying us, accordingly, with different results.
Root essential oil ofChrysopogon zizanioidesrelaxes rat isolated thoracic aorta – anex vivoapproach
Authors: Sivakumar Lekha , Chellappan David Raj , Sriramavaratharajan Venkatraman , Murugan Ramar 
Published: October 2020

AbstractRoot ofChrysopogon zizanioides(L.) Roberty has been used in Siddha system of medicine to treat hypertension. The present study was therefore to investigate the vasorelaxation effect of root essential oil ofC. zizanioidesusing rat isolated thoracic aortic rings. Chemical characterization of root essential oil was carried out using Gas Chromatography–Flame Ionization Detector (GC–FID) and Gas Chromatography–Mass Spectrometry (GC–MS). Essential oil nanoemulsion (EONE) was prepared and characterized. Vasorelaxant effect of EONE in endothelium-intact aortic rings precontracted with phenylephrine (PE) (1 µM) or KCl (80 mM) was investigated. Role of Ca2+, nitric oxide and K+channels in precontracted aortic rings were investigated to elucidate the mechanism of action of the essential oil. Further, the role of muscarinic and prostacyclin receptors in EONE induced relaxation was studied. The EONE significantly induced relaxation (Emax77.1 ± 4.87%) in PE precontracted aortic rings. The nitric oxide synthase, and cyclooxygenase inhibitors and potassium channel blockers have not significantly inhibited the vasorelaxation induced by EONE. However, EONE induced relaxation in precontracted endothelium-intact aortic rings was significantly inhibited by muscarinic receptor and calcium channel. The root essential oil ofC. zizanioidespossesses vasorelaxant effect through muscarinic pathway as well as acts as calcium channel blocker.
The Interaction of Munc18-1 Helix 11 and 12 with the Central Region of the VAMP2 SNARE Motif Is Essential for SNARE Templating and Synaptic Transmission
Authors: André Timon , Classen Jessica , Brenner Philipp , Betts Matthew J. , Dörr Bernhard , Kreye Susanne , Zuidinga Birte , Meijer Marieke , Russell Robert B. , Verhage Matthijs , Söllner Thomas H. 
Published: October 2020

AbstractSec1/Munc18 proteins play a key role in initiating the assembly of N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes, the molecular fusion machinery. Employing comparative structure modeling, site specific crosslinking by single amino acid substitutions with the photoactivatable unnatural amino acid p-Benzoyl-phenylalanine (Bpa) and reconstituted vesicle docking/fusion assays, we mapped the binding interface between Munc18-1 and the neuronal v-SNARE VAMP2 with single amino acid resolution. Our results show that helices 11 and 12 of domain 3a in Munc18-1 interact with the VAMP2 SNARE motif covering the region from layers −4 to +5. Residue Q301 in helix 11 plays a pivotal role in VAMP2 binding and template complex formation. A VAMP2 binding deficient mutant, Munc18-1 Q301D, does not stimulate lipid mixing in a reconstituted fusion assay. The neuronal SNARE-organizer Munc13-1, which also binds VAMP2, does not bypass the requirement for the Munc18-1·VAMP2 interaction. Importantly, Munc18-1 Q301D expression inMunc18-1deficient neurons severely reduces synaptic transmission, demonstrating the physiological significance of the Munc18-1·VAMP2 interaction.
KINETICS OF ANTIOXIDANTS DEGRADATION AND QUALITY CHANGES OF CITRON (Citrus medica) FRUIT JUICE CONCENTRATE DURING STORAGE
Authors: Islam Md Zohurul , Dey Pappu , Hoque Md. Mozammel , Monalisa Kamrunnaher 
Published: October 2020

The aim of the study was to develop fruit juice concentrate from Citron and its kinetic evaluation during storage at 10 ºC, 25 ºC and 40 ºC respectively, for 12th week. The effect of different temperatures on the quality of the juice concentrate was also investigated. The concentration of ascorbic acid in the juice concentrate was monitored after every week of storage. The results showed that degradation kinetics of ascorbic acid during storage was followed by the first-order kinetics. The degradation rates of ascorbic acid during storage at 10 ° C, 25 °C and 40 °C were obtained as 2.27 ± 0.24, 2.46 ± 0.31 and 2.56 ± 0.34 1/week respectively. The higher degradation rate was observed at 40 °C storage temperature. Temperature-dependent rate constants of ascorbic acid of citron juice concentrate was obeyed the Arrhenius relationship with higher R2 values as 0.96. Total antioxidant degradation was also high at higher storage temperatures. The amount of total phenolic content was decreasing at the first few weeks of storage, but later period of storage it was in gradually increasing trend. The storage study demonsrated that ascorbic acid, total polyphenol and antioxidant activity were not degraded at lower temperature after 12th week.
Callus induction and adventitious bud differentiation of Cyclocodon lancifolius (Roxb.) Kurz
Authors: Xi Yin-Kai , Wang Ye , Zeng Biao , Huang Heng-Yu , Yang Wu-Dei 
Published: October 2020

Background: Cyclocodon lancifolius (Roxb.) Kurz is a perennial medicinal and edible plant with a huge potential economic value. The wild resources of this plant are gradually scarce by the serious destruction of the habitat and the limitations of sexual reproduction. This is the first attempt to establish an in vitro reproductive system for the species.
Hypothesis: The suitable plant regulator types and its mass concentration range, combined with the explants, can induce the development of plants at various stages. We expected to establish an in vitro regeneration system of C. lancifolius based on these factors.
Species studied: Cyclocodon lancifolius
Study site and years of study: Yunnan Breeding and Cultivation Research and Development Center of Endangered and Daodi Chinese Medicinal Materials, Yunnan University of Chinese Medicine, from 2017 to 2019.
Methods: The plant regeneration of C. lancifolius was established by single factor, L9 (34) orthogonal and complete combination experiments.
Results: Stem segments were the best explants for callus induction on MS medium containing 0.05 mg·L-1 KT, 0.5 mg·L-1 6-BA and 0.5 mg·L-1 NAA. MS medium with 0.2 mg·L-1 TDZ and MS medium were used alternately as the culture method to conduct differentiation and proliferation of adventitious shoot. The optimal protocol for the rooting was MS medium combined with 0.1 mg·L-1 6-BA and 1.0 mg·L-1 NAA.
Conclusions: A rapid propagation system of C. lancifolius was established which provided a possible solution for the protection of wild resources and artificial cultivation.
Leprosy, impurity, and stigma in Vietnam
Authors: Ngoc Yen Le Hoang 
Published: October 2020

This Position Piece examines the nature of Vietnamese folk constructions of leprosy through Mary Douglas’s (1969) and Victor Turner’s (1967) works. Investigating Vietnamese explanations for the origins of leprosy and its channels of transmissions, symptoms, and consequences, I argue that these accounts are rooted in narratives of transition, transgression, the crossing of boundaries, and categorical confusion of various kinds. I argue that these deeply embedded perceptions of leprosy help to explain the existence of persistent stigma against leprosy in Vietnam, despite highly effective drug treatments and extensive state awareness programmes.
Cubical ethnography: Another kind of fieldwork
Authors: Martin Paula 
Published: October 2020

Studying the contemporary clinic necessitates rethinking what it means to both enter and access ‘the field’. In these Field Notes, I reflect on the beginnings of fieldwork and the processes of crafting research protocols which can stand up to formal ethics reviews. Rather than treating the process as a barrier to ‘real’ ethnographic research, I suggest that the mundane institutional realities of inserting oneself into a bureaucratic atmosphere form a particular—but no less valid—kind of ethnographic experience. I call this experience ‘cubicle ethnography’, after how the structures of the office—keys, badges, desktop computers—reflected negotiations of access and my own legitimacy as a visiting ethnographer.