bluuebunny/crossref_metadata_2025_split huggingface dataset:
Migration without interbreeding: evolutionary history of a highly selfing Mediterranean grass inferred from whole genomes
Authors: Stritt Christoph , Gimmi Elena L. , Wyler Michele , Bakali Abdelmonaim H. , Skalska Aleksandra , Hasterok Robert , Mur Luis A. J. , Pecchioni Nicola , Roulin Anne C. 
Published: September 2020

ABSTRACTWild plant populations show extensive genetic subdivision and are far from the ideal of panmixia which permeates population genetic theory. Understanding the spatial and temporal scale of population structure is therefore fundamental for empirical population genetics – and of interest in itself, as it yields insights into the history and biology of a species. In this study we extend the genomic resources for the wild Mediterranean grassBrachypodium distachyonto investigate the scale of population structure and its underlying history at whole-genome resolution. 86 accessions were sampled at local and regional scales in Italy and France, which closes a conspicuous gap in the collection for this model organism. The analysis of 196 accessions, spanning the Mediterranean from Spain to Iraq, suggests that the interplay of high selfing and seed dispersal rates has shaped genetic structure inB. distachyon. At the continental scale, the evolution inB. distachyonis characterized by the independent expansion of three lineages during the Upper Pleistocene. Today, these lineages may occur on the same meadow yet do not interbreed. At the regional scale, dispersal and selfing interact and maintain high genotypic diversity, thus challenging the textbook notion that selfing in finite populations implies reduced diversity. Our study extends the population genomic resources forB. distachyonand suggests that an important use of this wild plant model is to investigate how selfing and dispersal, two processes typically studied separately, interact in colonizing plant species.
Analysis of diffusion tensor imaging data from UK Biobank confirms dosage effect of 15q11.2 copy-number variation on white matter and shows association with cognition
Authors: Silva Ana I. , Kirov George , Kendall Kimberley M. , Bracher-Smith Mathew , Wilkinson Lawrence S. , Hall Jeremy , Ulfarsson Magnus O. , Walters G. Bragi , Stefansson Hreinn , Stefansson Kari , Linden David E. J. , Caseras Xavier 
Published: September 2020

AbstractBackgroundCopy-number variations at the 15q11.2 BP1-BP2 locus are present in 0.5 to 1.0% of the population, and the deletion is associated with a range of neurodevelopmental disorders. Previously, we showed a reciprocal effect of 15q11.2 copy-number variation on fractional anisotropy, with widespread increases in deletion carriers. We aim to replicate and expand these findings, using a larger sample of participants (n=30,930), higher resolution imaging, and examining the implications for cognitive performance.MethodsDiffusion tensor imaging measures from participants with no neurological/psychiatric diagnoses were obtained from the UK Biobank database. We compared 15q11.2 BP1-BP2 deletion (n=103) and duplication (n=119) carriers to a large cohort of control individuals with no neuropsychiatric copy-number variants (n=29,870). Additionally, we assessed how changes in white matter mediated the association between carrier status and cognitive performance.ResultsDeletion carriers showed increases in fractional anisotropy in the internal capsule and cingulum, and decreases in the posterior thalamic radiation, compared to both duplication carriers and controls (who had intermediate values). Deletion carriers had lower scores across cognitive tasks compared to controls, which were mildly influenced by white matter alterations. Reduced fractional anisotropy in the posterior thalamic radiation partially contributed to worse cognitive performance in deletion carriers.ConclusionsThis study, together with our previous findings, provides convergent evidence for a dosage-dependent effect of 15q11.2 BP1-BP2 on white matter microstructure. Additionally, changes in white matter were found to partially mediate cognitive ability in deletion carriers, providing a link between white matter changes in 15q11.2 BP1-BP2 carriers and cognitive function.
On demand MyD88 oligomerization is controlled by IRAK4 during Myddosome signaling
Authors: Deliz-Aguirre Rafael , Cao Fakun , Gerpott Fenja H. U. , Auevechanichkul Nichanok , Chupanova Mariam , Mun YeVin , Ziska Elke , Taylor Marcus J. 
Published: September 2020

AbstractA recurring feature of innate immune receptor signaling is the self-assembly of signaling proteins into oligomeric complexes. The Myddosome is an oligomeric complex that is required to transmit inflammatory signals from TLR/IL1Rs and consists of MyD88 and IRAK family kinases. However, the molecular basis for how Myddosome proteins self-assemble and regulate intracellular signaling remains poorly understood. Here, we developed a novel assay to analyze the spatiotemporal dynamics of IL1R and Myddosome signaling in live cells. We found that MyD88 oligomerization is inducible and initially reversible. Moreover, the formation of larger, stable oligomers consisting of more than 4 MyD88s triggers the sequential recruitment of IRAK4 and IRAK1. Notably, genetic knockout of IRAK4 enhanced MyD88 oligomerization, indicating that IRAK4 controls MyD88 oligomer size and growth. MyD88 oligomer size thus functions as a physical threshold to trigger downstream signaling. These results provide a mechanistic basis for how protein oligomerization might function in cell signaling pathways.
The wheat cytosolic glutamine synthetaseGS1.1modulates N assimilation and spike development by characterizing CRISPR-edited mutants
Authors: Wang Yazhou , Teng Wan , Wang Yanpeng , Ouyang Xiang , Xue He , Zhao Xueqiang , Gao Caixia , Tong Yiping 
Published: September 2020

AbstractGlutamine synthetase (GS) mediates the first step in the assimilation of inorganic nitrogen (N) into amino acids, however the function of GS encoding genes is not well understood in wheat (Triticum aestivum). We found that the cytosolicTaGS1.1was the major transcriptedGS1gene and was up-regulated by low-N availability. CRISPR/Cas9 mediated genome editing was employed to develop twogs1.1mutants with mutatedTaGS1.1-6A, −6B, and-6D. Both mutants had lower grains per spike and grain yield per plant than the wild type under both low-N and high-N conditions in field experiments. In a hydroponic culture treated with different N resources, the two mutants was more sensitive to low-N stress than the wild type, but showed similar sensitivity to high ammonium stress with the wild type. The growth deficiency and impaired spike development were associated with the imbalance of N metabolites in the mutant plants. During grain filling,TaGS1.1mutation reduced N translocation efficiency and delayed leaf N loss and grain N filling. Our results suggested thatTaGS1.1is important for N assimilation and remobilization, and required for wheat adaptation to N-limited conditions and spike development.HighlightThe wheat cytosolic glutamine synthetaseTaGS1.1is important for N assimilation and remobilization, and is required for wheat adaptation to low-N stress and spike development.
Employees’ identification and management control systems: a case study of modern policing
Authors: Cuganesan Suresh , Free Clinton 
Published: September 2020

PurposeThe authors examined how squad members within an Australian state police force perceived and attached enabling or coercive meanings to a suite of management control system (MCS) changes that were new public management (NPM) inspired.Design/methodology/approachThe authors conducted a longitudinal case study of a large Australian state police department utilizing an abductive research design.FindingsThe authors found that identification processes strongly conditioned the reception of the MCS changes introduced. Initially, the authors observed mixed interpretations of controls as both enabling and coercive. Over time, these changes were seen to be coercive because they threatened interpersonal relationships and the importance and efficacy of squads in combating serious and organized crime.Research limitations/implicationsThe authors contributed to MCSs literature by revealing the critical role that multifaceted relational and collective identification processes played in shaping interpretations of controls as enabling–coercive. The authors build on this to elaborate on the notion of employees’ centricity in the MCS design.Practical implicationsThis study suggests that, in complex organizational settings, the MCS design and change should reckon with pre-existing patterns of employees’ identification.Originality/valueThe authors suggested shifting the starting point for contemplating the MCS change: from looking at how what employees do is controlled to how the change impacts and how employees feel about who they are. When applied to the MCS design, employee centricity highlights the value of collaborative co-design, attentiveness to relational identification between employees, feedback and interaction in place of inferred management expectations and traditional mechanistic approaches.
Research on the construction of the semantic model for Chinese ancient architectures based on architectural narratives
Authors: Chen Jinju , Ou Shiyan 
Published: September 2020

Purpose
This paper aims to reorganize the relevant information of Chinese ancient architectures with the use of Semantic Web technologies and thus facilitate its deep discovery and usage.

Design/methodology/approach
This paper proposes an ontology model for Chinese ancient architectures based on architectural narratives theory. To verify the availability of the ancient architecture ontology, we designed and implemented three experiments, including semantic retrieval based on SPARQL query, semantic reasoning with the use of Jena reasoner and visual analysis based on the Chinese Online Digital Humanities Resources Platform.

Findings
The proposed ontology provided a solution for the semantic annotation of the unstructured information of Chinese ancient architectures. On this basis, deep knowledge services such as semantic retrieval, semantic reasoning and visual analysis can be provided.

Practical implications
The proposed semantic model of ancient architectures can effectively improve the organization and access quality of the semantic content of Chinese ancient architectures.

Originality/value
This paper focuses on the semantic modelling for the unstructured information of Chinese ancient architectures to semantically describe the related entities (e.g. persons, events, places and times) and uncover their relationships, and thus it made contribution to the deep semantic annotations on ancient architectures.
Friendly bureaucrats, formal rules and firms' investment decisions: evidence from a survey experiment in Russia
Authors: Yakovlev Andrei , Ivanov Denis 
Published: September 2020

PurposeThe purpose of this paper is to investigate the links between investment activity and personal contacts for small- and medium-sized firms with public officials at the subnational level in Russia.Design/methodology/approachA list-experiment design, using a survey of 21,000 Russian firms in 2017, was used to evaluate the importance of personal connections with officials for conducting business.FindingsA total of 27% of firms without investment and 37% with investment considered personal connections with officials an important factor for doing business. The importance of such contacts was lower in regions with a better investment climate. However, a higher proportion of firms were likely to invest in the regions where higher importance was placed on political connections. Therefore, in Russia in the mid-2010s, investment from politically connected firms did not crowd out investment from other firms.Research limitations/implicationsAlthough the available data did not allow causality to be defined, the research shows that political connections are important for investors in emerging markets and that the importance of political connections diminishes with improvement in the business climate.Originality/valueThis paper provides a quantitative estimate of the relationship between political connections and firm investment in Russia, an example of large emerging economy. This relationship is moderated by institutional quality at the subnational level. The results provide empirical support for the theory of limited access orders elaborated by North et al. (2009), and stress the importance of rents and their productive utilization for the development of emerging economies.
Digitally enabled advanced services: a socio-technical perspective on the role of the internet of things (IoT)
Authors: Schroeder Andreas , Naik Parikshit , Ziaee Bigdeli Ali , Baines Tim 
Published: September 2020

PurposeThe purpose of this study is to investigate how the internet of things (IoT) contributes to manufacturers' advanced services development and delivery. To better understand the creation of these IoT contributions, the study adopts a socio-technical research perspective, which expands the scope of the investigation and integrates the technological, information and social factors that enable these IoT contributions.Design/methodology/approachA multiple-case research method was employed to investigate the IoT contribution scenarios of 15 manufacturers who offer advanced services and to examine their dependence on other non-IoT factors, using thematic analysis.FindingsThe analysis identified five advanced services value propositions, which are enabled by nine “IoT-enabled information systems (IS) artefacts” that specify the distinct interactions between the technological, information and social subsystems supporting the manufacturers' advanced services value propositions.Originality/valueThe study advances the servitisation research by demonstrating that IoT technology on its own is insufficient for the creation of the IoT contributions. It shows, instead, the need for close interactions with a diverse range of other factors, which are often not considered when developing an IoT strategy. The study also introduces the IS artefact notion as a unit of analysis that constitutes an alternative to the commonly adopted techno-centric perspective used to conceptualise IoT contributions. The study and its findings add to the development of a socio-technical perspective on the IoT in advanced services and thereby suggests a number of theoretical and practical implications.
Networking capability and firm performance: the mediating role of market orientation and business process agility
Authors: Kurniawan Randy , Budiastuti Dyah , Hamsal Mohammad , Kosasih Wibowo 
Published: September 2020

Purpose
This study aims to examine the effect of networking capability through market orientation and business process agility on the firm performance of medium and large telecommunication technology providers in Indonesia.

Design/methodology/approach
Research data was collected from the executive management of telecommunication technology providers in Indonesia via a questionnaire survey to obtain 150 valid questionnaires for analysis. This study analysed the overall model fit and hypotheses through confirmatory factor analysis and structural equation modelling.

Findings
The results reveal that networking capability has a positive and significant effect on market orientation. However, networking capability does not have a significant direct effect on business process agility. The results also indicate that market orientation does not have a significant direct effect on firm performance but through the mediating role of business process agility.

Practical implications
The findings provide a practical foundation for the organisation’s networking capability to be framed by market orientation and business process agility to enhance firm performance.

Originality/value
The results indicate that market orientation mediates the relationship between networking capability and business process agility. The findings also reveal that business process agility mediates the relationship between market orientation and firm performance. This study also reconceptualises market orientation to embody the inter-partner coordination dimension and reconceptualise business process agility to embody business partner switching capability.
Adapting sales influence tactics in the information intensive era
Authors: Leach Mark P. , Epler Rhett T. , Wang Sijun 
Published: September 2020

Purpose
This paper aims to explore the usage of selling influence tactics across prospective customers with differing information-related needs.

Design/methodology/approach
The research study uses an exploratory critical incident technique (CIT) methodology to identify and examine salesperson influence tactics.

Findings
This study identifies and explores the use of salesperson influence tactics across three information-based conditions often encountered by salespeople (i.e. information seeking customers, informed customers with information inaccuracies and informed customers making sub-optimal decisions). Regardless of condition, salespeople readily used non-coercive information exchange tactics. Whereas, recommendations and ingratiation tactics were applied by more effective salespeople when interacting with informed customers with information deficiencies. Furthermore, salespeople report executing less effectively with prospects with inaccurate preexisting information and with prospects making flawed or sub-optimal decisions.

Research limitations/implications
Findings illustrate the need for a renewed focus on salesperson influence tactics, the conditions under which they are effective, and how salespeople adapt their influence tactics to various situations. The exploratory nature of this study limits the generalizability of findings.

Practical implications
A framework of adaptive selling strategies is proposed to help tackle new challenges faced by B2B salespeople in today’s information intensive market. When interacting with more informed customers, pre-existing information is often inaccurate and incomplete. Thus, salespeople must assess and address these flaws and gaps and can adapt their influence strategies to do so effectively.

Originality/value
Industrial buyers today have virtually unlimited avenues to conduct extensive research and gain supplier information without the aid of interactions with salespeople. Thus, salespeople often enter sales interactions when their prospects have significantly more information than ever before. By examining salesperson influence techniques in selling situations that vary based on prospective customer preexisting knowledge, this research provides guidance on how selling may need to change in a more information intensive era.
The bright side of geopolitical risk: evidence from Chinese firms
Authors: Oanh Ha Kieu , Hoang Khanh 
Published: September 2020

Purpose
The paper aims to investigate whether firms invest in corporate social responsibility (CSR) as a risk protection mechanism as the response to increased geopolitical risk (GPR).

Design/methodology/approach
The sample of this study includes non-financial listed firms on the Chinese stock market over 2000–2016. Several measures of CSR and GPR were used to examine the relationship between two factors. Further investigation is conducted to find out how increasing uncertainty in the business environment in both geopolitics and macroeconomic policy affects corporate decision-making regarding CSR.

Findings
GPR has a significant and positive effect on CSR, meaning that Chinese firms use CSR investment as an insurance mechanism against uncertainty arising from heightened geopolitical uncertainty. Further analysis indicates a negative joint effect of GPR and uncertainty in macroeconomic policy on CSR and shows that it can exhaust firms’ resources and offset their individual positive impacts on CSR at the extreme level of uncertainty. The findings are robust to the choices of proxies, model specifications and endogeneity concerns.

Originality/value
This study sheds light on the existing literature by providing empirical evidence on the positive relationship between GPR and CSR. The findings of this study support the risk management view, in which firms engage more in CSR as a form of insurance mechanism to react to geopolitical uncertainty. This is also the first empirical study investigating the joint effect of GPR and economic policy uncertainty on CSR.
Retirement saving behavior: evidence from UAE
Authors: Alkhawaja Sara Osama , Albaity Mohamed 
Published: September 2020

PurposeThis study aims to examine the effect of future time perspective (FTP), financial risk tolerance (FRT) and knowledge of financial planning for retirement (KFPR) on retirement saving behavior (RSB).Design/methodology/approachPrimary data were collected using a non-probability judgmental sampling technique. A questionnaire was distributed either manually (by hand) or through email where 370 United Arab Emirates (UAE) residents used in the higher education sector participated. The data analysis was obtained by using SPSS and Smart-PLS software. Structural equation modeling was used to evaluate the linear relationship between FTP, FRT, KFPR and RSB.FindingsThe findings from this study are consistent with previous research. FTP and KFPR had a significant positive effect, while FRT had an insignificant negative effect on RSB.Research limitations/implicationsThis study examined the effect of a few psychological variables on RSB and was conducted on a sample of university employees in the UAE. Additional research should examine environmental influences, individual differences and other psychological process factors. Furthermore, future research could extend the current study into other industries and other the Middle East and North Africa countries.Practical implicationsA better understanding of the factors that influence RSB can help working individuals, financial advisors/financial planning professionals, financial institutions and government/policymakers strengthen their understanding and initiatives toward retirement planning.Originality/valueTo the best of the authors knowledge, none of the previous research papers studied RSB in the UAE. Additionally, it is important to note that the results of this study can be generalized to all Gulf Cooperation Council countries because of the similar economic, political, ethical, social and cultural factors.