bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of scapular notching on clinical outcomes after reverse total shoulder arthroplasty
Authors: Jang Young Hoon , Lee Jeong Hyun , Kim Sae Hoon 
Published: November 2020

Aims Scapular notching is thought to have an adverse effect on the outcome of reverse total shoulder arthroplasty (RTSA). However, the matter is still controversial. The aim of this study was to determine the clinical impact of scapular notching on outcomes after RTSA. Methods Three electronic databases (PubMed, Cochrane Database, and EMBASE) were searched for studies which evaluated the influence of scapular notching on clinical outcome after RTSA. The quality of each study was assessed. Functional outcome scores (the Constant-Murley scores (CMS), and the American Shoulder and Elbow Surgeons (ASES) scores), and postoperative range of movement (forward flexion (FF), abduction, and external rotation (ER)) were extracted and subjected to meta-analysis. Effect sizes were expressed as weighted mean differences (WMD). Results In all, 11 studies (two level III and nine level IV) were included in the meta-analysis. All analyzed variables indicated that scapular notching has a negative effect on the outcome of RTSA . Statistical significance was found for the CMS (WMD –3.11; 95% confidence interval (CI) –4.98 to –1.23), the ASES score (WMD –6.50; 95% CI –10.80 to –2.19), FF (WMD –6.3°; 95% CI –9.9° to –2.6°), and abduction (WMD –9.4°; 95% CI –17.8° to –1.0°), but not for ER (WMD –0.6°; 95% CI –3.7° to 2.5°). Conclusion The current literature suggests that patients with scapular notching after RTSA have significantly worse results when evaluated by the CMS, ASES score, and range of movement in flexion and abduction. Cite this article: Bone Joint J 2020;102-B(11):1438–1445.
The Orthopaedic Trauma Society classification of open fractures
Authors: Trompeter Alex J. , Knight Ruth , Parsons Nick , Costa Matthew L. 
Published: November 2020

Aims To describe a new objective classification for open fractures of the lower limb and to correlate the classification with patient-centred outcomes. Methods The proposed classification was investigated within a cohort of adults with open fractures of the lower limb who were recruited as part of two large clinical trials within the UK Major Trauma Network. The classification was correlated with patient-reported Disability Rating Index (DRI) and EuroQol five-dimension questionnaire (EQ-5D) health-related quality of life in the year after injury, and with deep infection at 30 days, according to the Centers for Disease Control and Prevention definition of a deep surgical site infection. Results A total of 748 participants were included in the analysis. Of these, 288 (38.5%) had a simple open fracture and 460 (61.5%) had a complex fracture as defined by the new classification system. At 12 months, the mean DRI in the simple fracture group was 32.5 (SD 26.8) versus 43.9 (SD 26.1) in the complex fracture group (adjusted mean difference 8.19; 95% confidence interval (CI) 3.69 to 12.69). At 12 months the mean health-related quality of life (EQ-5D utility) in the simple fracture group was 0.59 (SD 0.29) versus 0.56 (SD 0.32) in the complex fracture group (adjusted mean difference -0.03; 95% CI -0.09 to 0.02). The differences in the rate of deep infection at 30 days was not statistically significant. Conclusion The Orthopaedic Trauma Society open fracture classification is based upon objective descriptors of the injury and correlates with patient-centred outcomes in a large cohort of open fractures of the lower limb. Cite this article: Bone Joint J 2020;102-B(11):1469–1474.
Patient-reported outcomes after corrective osteotomy for a symptomatic malunion of the distal radius
Authors: Stirling Paul H. C. , Oliver William M. , Ling Tan Huai , Brown Iain D. M. , Oliver Christopher W. , McQueen Margaret M. , Molyneux Sam G. , Duckworth Andrew D. 
Published: November 2020

Aims The primary aim of this study was to describe patient satisfaction and health-related quality of life (HRQoL) following corrective osteotomy for a symptomatic malunion of the distal radius. Methods We retrospectively identified 122 adult patients from a single centre over an eight-year period who had undergone corrective osteotomy for a symptomatic malunion of the distal radius. The primary long-term outcome was the Patient-Rated Wrist Evaluation (PRWE) score. Secondary outcomes included the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) score, the EQ-5D-5L score, complications, and the Net Promoter Score (NPS). Multivariate regression analysis was used to determine factors associated with the PRWE score. Results Long-term outcomes were available for 89 patients (72%). The mean age was 57 years (SD 15) and 68 were female (76%). The median time from injury to corrective osteotomy was nine months (interquartile range (IQR) 6 to 13). At a mean follow-up of six years (1 to 11) the median PRWE score was 22 (IQR 7 to 40), the median QuickDASH score was 11.4 (IQR 2.3 to 31.8), and the median EQ-5D-5L score was 0.84 (IQR 0.69 to 1). The NPS was 69. Multivariate regression analysis showed that the presence of an associated ulnar styloid fracture was the only significant independent factor associated with a worse PRWE score when adjusting for confounding variables (p = 0.004). Conclusion We found that corrective osteotomy for malunion of the distal radius can result in good functional outcomes and high levels of patient satisfaction. However, the presence of an ulnar styloid fracture may adversely affect function. Level of Evidence: III (cohort study). Cite this article: Bone Joint J 2020;102-B(11):1542–1548.
Diagnostic performance of congestion score index evaluated from chest radiography for acute heart failure in the emergency department: A retrospective analysis from the PARADISE cohort
Authors: Kobayashi Masatake , Douair Amine , Duarte Kevin , Jaeger Déborah , Giacomin Gaetan , Bassand Adrien , Jeangeorges Victor , Vuillaume Laure Abensur , Preud'homme Gregoire , Huttin Olivier , Zannad Faiez , Rossignol Patrick , Chouihed Tahar , Girerd Nicolas 
Published: November 2020

Background
Congestion score index (CSI), a semiquantitative evaluation of congestion on chest radiography (CXR), is associated with outcome in patients with heart failure (HF). However, its diagnostic value in patients admitted for acute dyspnea has yet to be evaluated.

Methods and findings
The diagnostic value of CSI for acute HF (AHF; adjudicated from patients’ discharge files) was studied in the Pathway of dyspneic patients in Emergency (PARADISE) cohort, including patients aged 18 years or older admitted for acute dyspnea in the emergency department (ED) of the Nancy University Hospital (France) between January 1, 2015 and December 31, 2015. CSI (ranging from 0 to 3) was evaluated using a semiquantitative method on CXR in consecutive patients admitted for acute dyspnea in the ED. Results were validated in independent cohorts (N = 224). Of 1,333 patients, mean (standard deviation [SD]) age was 72.0 (18.5) years, 686 (51.5%) were men, and mean (SD) CSI was 1.42 (0.79). Patients with higher CSI had more cardiovascular comorbidities, more severe congestion, higher b-type natriuretic peptide (BNP), poorer renal function, and more respiratory acidosis. AHF was diagnosed in 289 (21.7%) patients. CSI was significantly associated with AHF diagnosis (adjusted odds ratio [OR] for 0.1 unit CSI increase 1.19, 95% CI 1.16–1.22, p < 0.001) after adjustment for clinical-based diagnostic score including age, comorbidity burden, dyspnea, and clinical congestion. The diagnostic accuracy of CSI for AHF was >0.80, whether alone (area under the receiver operating characteristic curve [AUROC] 0.84, 95% CI 0.82–0.86) or in addition to the clinical model (AUROC 0.87, 95% CI 0.85–0.90). CSI improved diagnostic accuracy on top of clinical variables (net reclassification improvement [NRI] = 94.9%) and clinical variables plus BNP (NRI = 55.0%). Similar diagnostic accuracy was observed in the validation cohorts (AUROC 0.75, 95% CI 0.68–0.82). The key limitation of our derivation cohort was its single-center and retrospective nature, which was counterbalanced by the validation in the independent cohorts.

Conclusions
In this study, we observed that a systematic semiquantified assessment of radiographic pulmonary congestion showed high diagnostic value for AHF in dyspneic patients. Better use of CXR may provide an inexpensive, widely, and readily available method for AHF triage in the ED.
Seroprevalence of SARS-CoV-2 specific IgG antibodies in District Srinagar, northern India – A cross-sectional study
Authors: Khan S. Muhammad Salim , Qurieshi Mariya Amin , Haq Inaamul , Majid Sabhiya , Bhat Arif Akbar , Nabi Sahila , Ganai Nisar Ahmad , Zahoor Nazia , Nisar Auqfeen , Chowdri Iqra Nisar , Qazi Tanzeela Bashir , Kousar Rafiya , Lone Abdul Aziz , Sabah Iram , Nabi Shahroz , Sumji Ishtiyaq Ahmad , Kawoosa Misbah Ferooz , Ayoub Shifana 
Published: November 2020

Background
Prevalence of IgG antibodies against SARS-CoV-2 infection provides essential information for deciding disease prevention and mitigation measures. We estimate the seroprevalence of SARS-CoV-2 specific IgG antibodies in District Srinagar.

Methods
2906 persons >18 years of age selected from hospital visitors across District Srinagar participated in the study. We tested samples for the presence of SARS-CoV-2 specific IgG antibodies using a chemiluminescent microparticle immunoassay-based serologic test.

Results
Age- and gender-standardized seroprevalence was 3.6% (95% CI 2.9% to 4.3%). Age 30–69 years, a recent history of symptoms of an influenza-like-illness, and a history of being placed under quarantine were significantly related to higher odds of the presence of SARS-CoV-2 specific IgG antibodies. The estimated number of SARS-CoV-2 infections during the two weeks preceding the study, adjusted for test performance, was 32602 with an estimated (median) infection-to-known-case ratio of 46 (95% CI 36 to 57).

Conclusions
The seroprevalence of SARS-CoV-2 specific IgG antibodies is low in the District. A large proportion of the population is still susceptible to the infection. A sizeable number of infections remain undetected, and a substantial proportion of people with symptoms compatible with COVID-19 are not tested.
Circulating whole genome miRNA expression corresponds to progressive right ventricle enlargement and systolic dysfunction in adults with tetralogy of Fallot
Authors: Weldy Chad S. , Syed Saad Ali , Amsallem Myriam , Hu Dong-Qing , Ji Xuhuai , Punn Rajesh , Taylor Anne , Navarre Brittany , Reddy Sushma 
Published: November 2020

Introduction
The adult congenital heart disease population with repaired tetralogy of Fallot (TOF) is subject to chronic volume and pressure loading leading to a 40% probability of right ventricular (RV) failure by the 3rd decade of life. We sought to identify a non-invasive signature of adverse RV remodeling using peripheral blood microRNA (miRNA) profiling to better understand the mechanisms of RV failure.

Methods
Demographic, clinical data, and blood samples were collected from adults with repaired TOF (N = 20). RNA was isolated from the buffy coat of peripheral blood and whole genome miRNA expression was profiled using Agilent’s global miRNA microarray platform. Fold change, pathway analysis, and unbiased hierarchical clustering of miRNA expression was performed and correlated to RV size and function assessed by echocardiography performed at or near the time of blood collection.

Results
MiRNA expression was profiled in the following groups: 1. normal RV size (N = 4), 2. mild/moderate RV enlargement (N = 11) and 3. severe RV enlargement (N = 5). 267 miRNAs were downregulated, and 66 were upregulated across the three groups (fold change >2.0, FDR corrected p<0.05) as RV enlargement increased and systolic function decreased. qPCR validation of a subset of these miRNAs identified increasing expression of miRNA 28-3p, 433-3p, and 371b-3p to be associated with increasing RV size and decreasing RV systolic function. Unbiased hierarchical clustering of all patients based on miRNA expression demonstrates three distinct patient clusters that largely coincide with progressive RV enlargement. Pathway analysis of dysregulated miRNAs demonstrates up and downregulation of cell cycle pathways, extracellular matrix proteins and fatty acid synthesis. HIF 1α signaling was downregulated while p53 signaling was predicted to be upregulated.

Conclusion
Adults with TOF have a distinct miRNA profile with progressive RV enlargement and dysfunction implicating cell cycle dysregulation and upregulation in extracellular matrix and fatty acid metabolism. These data suggest peripheral blood miRNA can provide insight into the mechanisms of RV failure and can potentially be used for monitoring disease progression and to develop RV specific therapeutics to prevent RV failure in TOF.
On the treatment effect heterogeneity of antidepressants in major depression: A Bayesian meta-analysis and simulation study
Authors: Volkmann Constantin , Volkmann Alexander , Müller Christian A. 
Published: November 2020

Background
The average treatment effect of antidepressants in major depression was found to be about 2 points on the 17-item Hamilton Depression Rating Scale, which lies below clinical relevance. Here, we searched for evidence of a relevant treatment effect heterogeneity that could justify the usage of antidepressants despite their low average treatment effect.

Methods
Bayesian meta-analysis of 169 randomized, controlled trials including 58,687 patients. We considered the effect sizes log variability ratio (lnVR) and log coefficient of variation ratio (lnCVR) to analyze the difference in variability of active and placebo response. We used Bayesian random-effects meta-analyses (REMA) for lnVR and lnCVR and fitted a random-effects meta-regression (REMR) model to estimate the treatment effect variability between antidepressants and placebo.

Results
The variability ratio was found to be very close to 1 in the best fitting models (REMR: 95% highest density interval (HDI) [0.98, 1.02], REMA: 95% HDI [1.00, 1.02]). The between-study standard deviation τ under the REMA with respect to lnVR was found to be low (95% HDI [0.00, 0.02]). Simulations showed that a large treatment effect heterogeneity is only compatible with the data if a strong correlation between placebo response and individual treatment effect is assumed.

Conclusions
The published data from RCTs on antidepressants for the treatment of major depression is compatible with a near-constant treatment effect. Although it is impossible to rule out a substantial treatment effect heterogeneity, its existence seems rather unlikely. Since the average treatment effect of antidepressants falls short of clinical relevance, the current prescribing practice should be re-evaluated.
Factors associated with postmenstrual age at full oral feeding in very preterm infants
Authors: Brun Grégoire , Fischer Fumeaux Céline J. , Giannoni Eric , Bickle Graz Myriam 
Published: November 2020

Aim
We aimed to identify variables associated with gestational age at full oral feeding in a cohort of very preterm infants.

Methods
In this retrospective study, all infants born below 32 weeks of gestation and admitted to a level III neonatal unit in 2015 were included. We dichotomized our population of 122 infants through the median age at full oral feeding, and explored which variables were statistically different between the two groups. We then used linear regression analysis to study the association between variables known from the literature and variables we had identified and age at full oral feeding.

Results
The median postnatal age at full oral feeding was 36 6/7weeks post menstrual age (Q1-Q3 35 6/7-392/7), and was associated with the duration of hospital of stay. In the univariable linear regression, the variables significantly associated with full oral feeding were gestational age, socioeconomic status, sepsis, patent ductus arteriosus, duration of supplementary oxygen, of non-invasive and invasive ventilation, and bronchopulmonary dysplasia. In the multivariable regression analysis, duration of non-invasive ventilation and oxygen therapy, bronchopulmonary dysplasia, and patent ductus arteriosus were associated with an older age at full oral feeding, with bronchopulmonary dysplasia the single most potent predictor.

Discussion
Lung disease severity is a major determinant of age at full oral feeding and thus length of stay in this population. Other factors associated with FOF include socioeconomic status and patent ductus arteriosus, There is a need for research addressing evidence-based bundles of care for these infants at risk of long-lasting feeding and neurodevelopmental impairments.
GERAKAN AYO SEKOLAH DI KABUPATEN BOJONEGORO: PENINGKATAN SUMBER DAYA MANUSIA MELALUI PENDIDIKAN UNTUK MENYONGSONG BONUS DEMOGRAFI
Authors: Satiti Sonyaruri 
Published: November 2020

Improving the quality of human resources through education is one of the ways to benefit from the window of opportunity. The Government of Indonesia and many local governments have been conducting programs to provide easier access to education to prevent dropouts. The Local Government of Bojonegoro has been implementing a program called "Ayo Sekolah" to curb dropouts. This paper aims to describe the conditions of education in Bojonegoro District and the implementation of the â€œAyo Sekolahâ€ Program in Bojonegoro District. The analysis is based onÂ the result of research on the program. The research used a quantitative and qualitative approach. Qualitative data is collected through in-depth interviews, while secondary data are used for quantitative analysis. The result of the study shows that the â€œAyo Sekolahâ€ Program in Bojonegoro District that has been running since 2015 has significantly reduced dropout rates. The percentage of the drop-off rates for Bojonegoro Regency high school/vocational/MA in 2013-2017 decreased even though only 0.20 percent.
ANALISA ENGINE PROPELLER MATCHING (EPM) PADA KAPAL RESCUE BOAT KARENA PERUBAHAN TAHAP POWERING PROCESS
Authors: Baital Muhammad Sawal , Putranto Ari Bawono , Waluyo Bambang Sri 
Published: November 2020

This study is to investigate compatibility between installed main engine in ship with propeller design using theoretical approach and data series. A triple screw rescue boat conducted hard chain hull was used for study and analyze the effect of the changes in powering process stage by observing the result of open water efficiency based on Wageningen Data Series with cavitation analysis has been neglected. The study is considered using intersection between propeller thrust with thrust coefficient and open water efficiency on Wageningen B-Series for fixed pitch propeller. The result indicated that propeller characteristic B5-76 with 41% of efficiency has compatibility with specification of installed main engine.
External strengthening of reinforced concrete beam with opening by bamboo fiber reinforced composites
Authors: Chin Siew Choo , Tee Kong Fah , Tong Foo Sheng , Doh Shu Ing , Gimbun Jolius 
Published: November 2020

AbstractThis paper presents the structural behaviour of reinforced concrete (RC) beams with and without openings strengthened externally with bamboo fiber reinforced composite (BFRC) plates in shear and flexure, respectively. Mechanical properties include tensile and flexural strength of epoxy, polyester and vinyl-ester based BFRC plates with 0%, 10%, 20%, 30% and 40% fiber volume fractions were evaluated. A total of fourteen beams were cast to evaluate the structural behaviour of RC beams strengthened with BFRC plates. All the beams were tested to failure under four-point bending. The results presented were in terms of load–deflection behaviour, failure mode and crack pattern. A comparison was also made between the performance of epoxy, polyester and vinyl-ester based BFRC plates in shear strengthening of RC beams with openings. Results revealed that the presence of openings in the shear zone reduced the original beam capacity of the control beam to about 52–55%. Shear strengthening of RC beams with openings using epoxy based BFRC plates showed significant improvement in regaining the beam structural capacity to approximately 32–36% higher than the un-strengthened beams. Meanwhile, strengthening of RC beams in flexure with epoxy based BFRC plates managed to regain the beam original capacity up to 98% of the control beam. Bamboo fiber composite reinforced with epoxy, polyester and vinyl-ester resins of 40% fiber volume fraction managed to regain the beam original capacity up to 82%. It was found that BFRC plates could divert and mitigate the formation of cracks away from the strengthened region as well as improved the beam ductility.
Limb length discrepancy and gait parameters of amateur football players in Lagos State, Nigeria
Authors: AKODU ASHIYAT KEHINDE , Oluwatomisin Adeoye Akindele Oluwatomisin Adeoye 
Published: November 2020

Background: Football is a widely played sport globally. Limb length discrepancies have been found to be common among football players and these may lead to abnormal gait.
Objectives: The purpose of this study was to determine the relationship between limb length discrepancy (LLD) and gait parameters of amateur football players in Lagos State, Nigeria.
Methods: Eighty-nine amateur football players participated in the cross-sectional study. They were recruited from different stadia in Lagos State. Limb length and gait parameters were measured using tape and footprint measurements.
Results: The prevalence of real limb length discrepancy among the participants was 75% (n = 67). The results of this study showed that the right leg was the shorter leg in 60% (n = 53) of the participants. There was no significant correlation between gait parameters and limb length measurement.
Conclusion: Although limb length discrepancy is common among amateur football players in Lagos State, the relationship between limb length and gait parameters is weak.
“I was refused an ELT job for being non-native”-- An Insight into the Native Speaker Ideology in ELT
Authors: Ren Ke 
Published: November 2020

In English language teaching (ELT), compared with non-native English speaker English teachers (NNESTs), native English speaker teachers (NESTs) seemingly gain prominence and are often taken for granted as better English teachers for non-native speaker students, which is described as the native speaker ideology (NS ideology) in this area. In foregoing research of this issue, much attention has been paid to the comparison of NESTs and NNESTs, or students’ perceptions on NESTs and NNESTs, while studies having a general picture of the NS ideology are scant. On the basis of literature review, the paper is attempted to have an overall picture of the NS ideology in ELT, with a focus on its causes, its effects on English teaching and learning, and its irrational aspects. In the end, corresponding implications for English teaching and learning are proposed based on the foregoing discussions.