bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and cost‐effectiveness of nurse‐led cognitive behavioral group therapy for recovery of self‐esteem among individuals with mental disorders: A single‐group pre‐post study
Authors: Kunikata Hiroko , Yoshinaga Naoki , Yoshimura Kensuke , Furushima Daisuke 
Published: August 2020

AbstractAimTo investigate whether the addition of a nurse‐led cognitive behavioral group therapy for recovery of self‐esteem (CBGTRS) program to usual care for individuals with mental disorders can improve clinical outcomes and reduce direct medical costs.MethodsThis study employed single‐group pre‐post design, and recruited 51 community‐dwelling individuals with mental disorders. Participants received 12 weekly CBGTRS sessions by a nurse in addition to usual care. The primary outcome measure was the level of self‐esteem, with other clinical outcomes and direct medical costs. The clinical outcomes were measured at pre‐intervention (T0), intervention midpoint (T1), immediate post‐intervention (T2), and 3 months post‐intervention (T3). Direct medical costs were calculated for 3 months pre‐intervention (A0), 3 months post‐intervention (A1), between 4–6 months post‐intervention (A2), and between 7–9 months post‐intervention (A3).ResultsSelf‐esteem scores were significantly improved from T0 to T2 and T3 (p = .009 and .006, respectively); within‐group effect sizes were .49 (small) for T0‐T2, and .51 (medium) for T0‐T3. Other secondary clinical outcomes for mood, cognitive bias, global functioning, and quality of life were also improved by T3 (all p < .05). The mean total direct medical costs were significantly reduced from A0 (49,569.51 JPY) to A2 and A3 (21,845.76 JPY and 25,981.69 JPY, respectively) (p = .003 and .017, respectively).ConclusionsThe results suggest that nurse‐led CBGTRS for mental disorders is a potentially effective approach in improving self‐esteem and other clinical outcomes, and in reducing direct medical costs. Further controlled studies that address the limitations of this study are required.
Relaxant effect of diallyl sulfide on nonpregnant rat uterus: Involvement of voltage‐dependent calcium channels
Authors: Efe Oğuzhan E. , Lux K. Michael , Emre Aydingöz Selda , Tuncer Meral 
Published: August 2020

AbstractAimWe aimed to determine the effect and mechanism of action of diallyl sulfide (DAS), an active component of sulfur‐containing foods such as garlic on rat uterine activity.MethodsIsometric tension changes in longitudinal uterine strips obtained from 20 female Sprague–Dawley rats (250–300 g) in estrus stage of estrous cycle were studied in isolated organ baths containing Krebs–Henseleit solution.ResultsDiallyl sulfide (10−8–10−6 M) caused a concentration‐dependent relaxation on KCl (60 mM)‐induced contractions and inhibited spontaneous peristaltic activity of uterine strips (P < 0.05). None of the following antagonists significantly changed the inhibitory effect of DAS on both KCl‐precontracted uterine strips and spontaneous peristaltic activity of the uterus (P > 0.05): nitric oxide synthase inhibitor L‐NAME (10−4 M), hydrogen sulfide‐producing enzymes cystation β synthase and cystation γ‐lyase inhibitors, aminooxyacetic acid (10−4 M) and propargylglycine (10−3 M) and nonselective cyclooxygenase inhibitor indomethacin (10−4 M). However, in calcium‐free Krebs solution containing high KCl (30 mM), DAS significantly inhibited CaCl2 (10−5–10−2 M)‐induced uterine contractions in a concentration‐dependent manner (P < 0.05).ConclusionDiallyl sulfide has a relaxing effect on KCl‐contracted rat uterus strips and an inhibitory effect on spontaneous uterine activity, possibly by decreasing the calcium influx into the cytoplasm of uterine smooth muscle cells.
Clinical presentations and antimicrobial susceptibilities of Corynebacterium cystitidis associated with renal disease in four beef cattle
Authors: Smith Joe S. , Krull Adam C. , Schleining Jennifer A. , Derscheid Rachel J. , Kreuder Amanda J. 
Published: August 2020

AbstractBackgroundRenal disease caused by Corynebacterium cystitidis in beef cattle may be misclassified as Corynebacterium renale, and limited information about C. cystitidis infections in beef cattle currently is available.ObjectiveTo describe clinical presentation, diagnosis, minimum inhibitory concentrations (MICs), and outcome of renal disease caused by C. cystitidis in beef cattle.MethodsRetrospective case series.AnimalsFour client‐owned beef cattle.ResultsAll affected cattle had anorexia as a primary complaint. Of the 3 that had ante‐mortem diagnostic tests performed, all had pyelonephritis based on azotemia in combination with urinalysis and ultrasonographic findings. Cultures yielded C. cystitidis which was identified by biochemical testing, 16S RNA sequencing, and mass spectrometry. All affected cattle deteriorated despite aggressive treatment, indicating that C. cystitidis infections in beef cattle may carry a poor prognosis. Bacterial isolates collected from the 4 cattle showed similarities in MICs for ampicillin, florfenicol, gentamicin, neomycin, sulfadimethoxine, trimethoprim sulfonamide, and tylosin.Conclusions and clinical importanceCorynebacterium cystitidis should be considered in the differential diagnosis of cattle with renal disease. Definitive diagnosis of C. cystitidis as compared to C. renale may be challenging.
Size matters for OTC market makers: General results and dimensionality reduction techniques
Authors: Bergault Philippe , Guéant Olivier 
Published: August 2020

AbstractIn most over‐the‐counter (OTC) markets, a small number of market makers provide liquidity to other market participants. More precisely, for a list of assets, they set prices at which they agree to buy and sell. Market makers face therefore an interesting optimization problem: they need to choose bid and ask prices for making money while mitigating the risk associated with holding inventory in a volatile market. Many market‐making models have been proposed in the academic literature, most of them dealing with single‐asset market making whereas market makers are usually in charge of a long list of assets. The rare models tackling multiasset market making suffer however from the curse of dimensionality when it comes to the numerical approximation of the optimal quotes. The goal of this paper is to propose a dimensionality reduction technique to address multiasset market making by using a factor model. Moreover, we generalize existing market‐making models by the addition of an important feature: the existence of different transaction sizes and the possibility for the market makers in OTC markets to answer different prices to requests with different sizes.
Effect of polyethylene cover on the treatment of exposure keratopathy in ICU
Authors: Kocaçal Elem , Eşer İsmet , Eğrilmez Sait 
Published: August 2020

AbstractBackgroundExposure keratopathy may lead to serious complications such as microbial keratitis, corneal perforation, and visual impairment if not treated.AimTo compare the effect of carbomer eye drops when used alone and in combination with polyethylene covers in the healing of exposure keratopathy.MethodsA single blind randomized‐controlled trial (RCT) in two intensive care units (ICUs) was carried out in a university hospital in Western Turkey between September 2011 and December 2012. The control group received only carbomer, eye drops while the intervention group received both carbomer eye drops and polyethylene covers. The primary outcome was the decrease or absence of corneal damage, which refers to healing. Corneal damage was followed up with a fluorescein dye test (decrease/absence of the corneal staining) by the same ophthalmologist for 10 days.ResultsA total of 43 corneas in 24 patients were studied. Corneal epithelial defects decreased in the intervention group by day 2 and progressed or remained unchanged in the control group every day (P = .001). Patient characteristics did not affect the grade ranges of corneal staining in the groups except for level of consciousness.ConclusionCarbomer eye drops, when used in combination with polyethylene covers, were effective in managing exposure keratopathy.Relevance to clinical practiceCorneal damage and further ocular complications can be reduced with the utilization of polyethylene covers in nursing care and treatment.
Improved Transferability of Data‐Driven Damage Models Through Sample Selection Bias Correction
Authors: Wagenaar Dennis , Hermawan Tiaravanni , van den Homberg Marc J. C. , Aerts Jeroen C. J. H. , Kreibich Heidi , de Moel Hans , Bouwer Laurens M. 
Published: August 2020

AbstractDamage models for natural hazards are used for decision making on reducing and transferring risk. The damage estimates from these models depend on many variables and their complex sometimes nonlinear relationships with the damage. In recent years, data‐driven modeling techniques have been used to capture those relationships. The available data to build such models are often limited. Therefore, in practice it is usually necessary to transfer models to a different context. In this article, we show that this implies the samples used to build the model are often not fully representative for the situation where they need to be applied on, which leads to a “sample selection bias.” In this article, we enhance data‐driven damage models by applying methods, not previously applied to damage modeling, to correct for this bias before the machine learning (ML) models are trained. We demonstrate this with case studies on flooding in Europe, and typhoon wind damage in the Philippines. Two sample selection bias correction methods from the ML literature are applied and one of these methods is also adjusted to our problem. These three methods are combined with stochastic generation of synthetic damage data. We demonstrate that for both case studies, the sample selection bias correction techniques reduce model errors, especially for the mean bias error this reduction can be larger than 30%. The novel combination with stochastic data generation seems to enhance these techniques. This shows that sample selection bias correction methods are beneficial for damage model transfer.
Truth or Accuracy?
Authors: Zahnoun Farid 
Published: August 2020

AbstractAn important conceptual shift can be discerned within contemporary philosophy of perception. Whereas proponents of the idea that perceptual experience is contentful used to relate perceptual content to truth conditions, authors nowadays prefer to think of perception as evaluable for accuracy. This transition from truth to accuracy becomes particularly clear in the influential work of Susanna Siegel. Importantly, Siegel actually provides an extensive argument for this shift. Yet this article argues that this transition from truth to accuracy conditions is ill‐motivated, confused and pernicious for the so‐called Content View, the view that all experience has truth or accuracy evaluable content.
Inactivation of Japanese encephalitis virus in plasma by methylene blue combined with visible light and in platelet concentrates by ultraviolet C light
Authors: Rustanti Lina , Hobson‐Peters Jody , Colmant Agathe M. G. , Hall Roy A. , Young Paul R. , Reichenberg Stefan , Tolksdorf Frank , Sumian Chryslain , Gravemann Ute , Seltsam Axel , Marks Denese C. , Faddy Helen M. 
Published: August 2020

BackgroundJapanese encephalitis virus (JEV) is endemic to tropical areas in Asia and the Western Pacific. It can cause fatal encephalitis, although most infected individuals are asymptomatic. JEV is mainly transmitted to humans through the bite of an infected mosquito, but can also be transmitted through blood transfusion. To manage the potential risk of transfusion transmission, pathogen inactivation (PI) technologies, such as THERAFLEX MB‐Plasma and THERAFLEX UV‐Platelets systems, have been developed. We examined the efficacy of these two PI systems to inactivate JEV.Study Design and MethodsJapanese encephalitis virus–spiked plasma units were treated using the THERAFLEX MB‐Plasma system (visible light doses, 20, 40, 60, and 120 [standard] J/cm2) in the presence of methylene blue at approximately 0.8 μmol/L and spiked platelet concentrates (PCs) were treated using the THERAFLEX UV‐Platelets system (UVC doses, 0.05, 0.10, 0.15, and 0.20 [standard] J/cm2). Samples were taken before the first and after each illumination dose and tested for infectivity using an immunoplaque assay.ResultsTreatment of plasma with the THERAFLEX MB‐Plasma system resulted in an average of 6.59 log reduction in JEV infectivity at one‐sixth of the standard visible light dose (20 J/cm2). For PCs, treatment with the THERAFLEX UV‐Platelet system resulted in an average of 7.02 log reduction in JEV infectivity at the standard UVC dose (0.20 J/cm2).ConclusionsThe THERAFLEX MB‐Plasma and THERAFLEX UV‐Platelets systems effectively inactivated JEV in plasma or PCs, and thus these PI technologies could be an effective option to reduce the risk of JEV transfusion transmission.
How to verify patient identity and blood product compatibility using an electronic bedside transfusion system
Authors: Staples Sophie , O'Callaghan Clare , Pavord Sue , Staves Julie , Murphy Michael F. 
Published: August 2020

AbstractTransfusion of an incorrect blood component is an important avoidable serious hazard of transfusion resulting from process errors. Our group and others have taken advantage of new technology and developed electronic transfusion systems for safe transfusion practice in a previous studies. They allow the clinical staff to correctly identify the patient and the blood product at the bedside, ensuring the right blood product is given to the right patient. This video is to demonstrate the process and not to promote any specific product. It is a follow up our previous video clip on electronic remote blood issue in a previous study. The process for correct patient identification originates from the wristband, which contains the patient identification details in a 2D barcode and is printed from the electronic patient record system. These details are associated with the blood sample through using a portable printer to produce a label for the sample tube. The patient details are scanned into the blood bank laboratory information system (LIS) and are then printed on a compatibility label by the LIS, which also contains a 2‐dimensional barcode, and is then attached to the blood product. Following an initial visual check of these details by the clinical staff, the electronic bedside system requires that both the patient wristband barcode and the blood product compatibility barcode are scanned. This will electronically verify at the patient's bedside that the right unit is to be given to the right patient. This is the final step in ensuring end‐to‐end electronic control and safe transfusion practice.
Influence of barbed epitendinous sutures combined with a core locking‐loop suture to repair experimental flexor tendon lacerations
Authors: Eby Adam C. , Duffy Daniel J. , Chang Yi‐Jen , Gaffney Lewis , Fisher Matthew B. , Moore George E. 
Published: August 2020

AbstractObjectiveTo determine the influence of barbed epitendinous sutures (ES) on the biomechanical properties and gap formation of repaired canine tendons.Study designEx vivo, experimental study.Sample populationEighty (n = 16/group) canine superficial digital flexor tendons (SDFT).MethodsAfter transection, SDFT were repaired with a locking‐loop (LL) pattern alone (group 1), an LL + smooth ES with monofilament suture (group 2), an LL + V‐loc‐ES (group 3), an LL + Quill‐ES (group 4), or an LL + Stratafix‐ES (group 5). All core LL repairs were performed with 0 USP polypropylene, and all ES were placed with 2‐0 USP equivalent. Constructs were preloaded and tested to failure. Yield, peak, and failure loads; occurrence of gap formation; and failure modes were compared.ResultsYield loads were greater for groups 2 and 5 (P < .0001). Peak and failure loads were greater when an ES was used (P < .005), especially for groups 2 and 5 (P < .0001). Groups with an ES required higher loads to generate 1‐ and 3‐mm gaps compared with specimens without an ES (P < .002). Force to create 1‐ and 3‐mm gaps was greater for group 5 (P < .0001) and groups 2 and 5 (P < .0001), respectively. Failure mechanism did not differ (P = .092) between ES groups, consisting of suture breakage in 51 of 64 constructs compared with pull‐through in seven of 16 group 1 constructs.ConclusionEpitendinous suture placement improved the biomechanical properties of repaired tendons. Stratafix barbed suture performed better as an ES compared with other barbed sutures and similarly to monofilament suture.Clinical significanceStratafix barbed suture eliminates the requirement for knot tying and seems to be equivalent to smooth monofilament suture when used as an ES in this pattern.
Impact of Exit Duct Dynamic Response on Compressor Stability
Authors: Zhang Wenqiang , Vahdati Mehdi , Zhao Fanzhou 
Published: August 2020

Abstract
Abrupt distortions can appear as a result of transient crosswind or during rapid aircraft maneuvers. Such distortions are known to reduce the aerodynamic stability of engines and therefore present a major concern to all aero-engine manufacturers. To assess the aerodynamic stability of fan blades due to distortions, rig tests are usually carried out to establish the loss in stall margin. In such test campaigns, an exit duct (which is followed by a nozzle) is placed downstream of the fan blade, and the operating condition of the fan is controlled by this nozzle. It is shown in this paper that in such rig tests, the length of duct downstream of a fan has a significant impact on fan stall margin. The key contributor for such interaction is the dynamic response of the exit duct, and the aerodynamic stability of the fan is affected by the acoustic reflection from the exit nozzle. To study the underlying physics, transient response in the exit duct downstream of a transonic fan stage was studied numerically using a simplified model. Simulation results, along with calculations based on analytical theories, confirmed the generation, propagation, and reflection of waves induced by the inlet distortion. A quantitative relationship concerning the lengths of the compression system is introduced which determines whether a duct setup would have beneficial or detrimental influences on compressor aerodynamic stability. The findings of this research have great implications for the stability assessment of fans as the stability margin can be affected by the waves generated in bypass ducts.
Effects of Euler Angles of Vertical Cambered Otter Board on Hydrodynamics Based on Response Surface Methodology and Multi-Objective Genetic Algorithm
Authors: Wang Gang , Huang Liuyi , Wang Lei , Zhao Fenfang , Wang Xinxin , Wan Rong 
Published: August 2020

Abstract
In this present work, effects of three Euler angles (angle of attack (AOA), angle of trim (AOT), and angle of pitch (AOP)) of vertical cambered otter board on hydrodynamic characteristics (drag coefficient (Cd), lift coefficient (Cl), center-of-pressure coefficients (Cp)) were studied based on numerical simulation combined with Kriging response surface methodology (KRSM) and multi-objective genetic algorithm (MOGA). Wind tunnel experiments were carried out to validate the accuracy of the response surface based on numerical simulation. It was demonstrated that AOA had noticeable effects on Cd and Cl, while AOT and AOP had fewer effects. The working posture of the otter board was recommended to lean inward (0 deg–6 deg) and forward (−10 deg–0 deg) to improve the lift-drag ratio without sacrificing Cl. The influences of AOT and AOP on positions of center-of-pressure points were less significant than that of AOA and decreasing with the increase of AOA. Besides, the response surface of hydrodynamic coefficients around the critical AOA was a decent indicator of the occurrence of stall. Finally, three candidate cases were selected to satisfy the high working efficiency by MOGA, which was consistent with the above recommendations. This study provided a scientific reference of response surface experimental investigations methodology in the fishery engineering and the configuration of Euler angles of otter board.
Modeling and Optimization for the Dynamic Performance of Vertical-Axis Wind Turbine Composite Blades
Authors: Ghoneam Sobhy , Hamada Ahmed , Sherif Taha 
Published: August 2020

Abstract
This article presents a study of modeling and optimization for the dynamic performance of wind turbine composite material blades and investigates the effects of composite material stacking sequence in addition to some design parameters such as twist angle (ɸ) and aspect ratio (AR) on the whole wind turbine performance. The two-stage Savonius rotor VAWT composite blades are designed and simulated within the solidworks simulation 2020 package. Modified mechanical parameters are introduced to improve the scalability, reliability, and accuracy of the developed models. The lamination plate theory is used to compute the equivalent mechanical properties for each composite blade. The finite element analyses (FEAs) are conducted to investigate the dynamic characteristics (frequency and associated mode shapes) of wind turbine models. Taguchi tools such as analysis of variance (ANOVA), signal-to-noise (S/N) ratio and additive model were employed to evaluate and obtain the significant factors and determine the optimal combination levels of wind turbine design parameters. Mathematical modeling based on response surface methodology (RSM) has been established. The analysis of results shows that the aspect ratio with a contribution of 48.08% had the dominant impact on the rotor performance followed by the stacking sequence and twist angle.
Association Between Physical Activity Intensity Levels and Arterial Stiffness in Healthy Children
Authors: Heil Lisa , Oberhoffer Renate , Böhm Birgit 
Published: August 2020

Background: Physical activity (PA) has a substantial impact on arterial stiffness in adults; however, evidence regarding children is scarce. The aim of this study was to examine the association between objectively measured PA with different intensities and surrogate measures of arterial stiffness in healthy children. Methods: Altogether, 80 children (41 girls and 39 boys, ranging from 8–11 y) participated in this prospective, cross-sectional study. Sedentary time and PA of light, moderate, and vigorous intensity levels were measured over a period of 7 days by accelerometry. Arterial stiffness parameters, including pulse wave velocity and central systolic blood pressure (cSBP), were noninvasively assessed by the oscillometric Mobil-O-Graph. Associations were tested using multiple linear regressions with adjustments for potential confounders (α ≤ .05). Results: PA of moderate intensity was negatively associated with cSBP (β = −0.266, P = .017). PA of vigorous intensity was inversely related to pulse wave velocity (β = −0.225, P = .045) and cSBP (β = −0.286, P = .010), respectively. Conclusion: Higher time spent in PA of moderate and vigorous intensity is associated with reduced pulse wave velocity and lower cSBP values in children. It suggests that PA is a favorable determinant of arterial health.