bluuebunny/crossref_metadata_2025_split huggingface dataset:
An NF-κB/IRF1 axis programs cDC1s to drive anti-tumor immunity
Authors: Ghislat G , Cheema AS , Baudoin E , Verthuy C , Ballester PJ , Crozat K , Attaf N , Dong C , Milpied P , Malissen B , Auphan-Anezin N , Vu Manh TP , Dalod M , Lawrence T 
Published: December 2020

AbstractConventional type 1 dendritic cells (cDC1s) are critical for anti-tumor immunity. They acquire antigens from dying tumor cells and cross-present them to CD8+T cells, promoting the expansion of tumor-specific cytotoxic T cells. However, the signaling pathways that govern the anti-tumor functions of cDC1s are poorly understood. We mapped the molecular pathways regulating intra-tumoral cDC1 maturation using single cell RNA sequencing. We identified NF-κB and IFN pathways as being highly enriched in a subset of functionally mature cDC1s. The specific targeting of NF-κB or IFN pathways in cDC1s prevented the recruitment and activation of CD8+T cells and the control of tumor growth. We identified an NF-κB-dependent IFNγ-regulated gene network in cDC1s, including cytokines and chemokines specialized in the recruitment and activation of cytotoxic T cells. We used single cell transcriptomes to map the trajectory of intra-tumoral cDC1 maturation which revealed the dynamic reprogramming of tumor-infiltrating cDC1s by NF-κB and IFN signaling pathways. This maturation process was perturbed by specific inactivation of either NF-κB or IRF1 in cDC1s, resulting in impaired expression of IFN-γ-responsive genes and consequently a failure to efficiently recruit and activate anti-tumoral CD8+T cells. Finally, we demonstrate the relevance of these findings to cancer patients, showing that activation of the NF-κB/IRF1 axis in association with cDC1s is linked with improved clinical outcome. The NF-κB/IRF1 axis in cDC1s may therefore represent an important focal point for the development new diagnostic and therapeutic approaches to improve cancer immunotherapy.One Sentence SummaryNF-κB and IRF1 coordinate intra-tumoral cDC1 maturation and control of immunogenic tumor growth.
Does experience with agricultural loans improve farmers' well-being? Evidence from Benin
Authors: Sagbo Nicaise Sheila M. , Kusunose Yoko 
Published: December 2020

PurposeThe purpose of this study is to examine the effect of loans provided by Benin's largest microlender.Design/methodology/approachA pipeline design and matching techniques contribute for identifying the causal effect. The loan treatment considered is loan experience. It includes program entry timing, take-up frequency and the amount obtained over six years. The study uses a cluster analysis to create comparison groups.FindingsExperience with agricultural loans has a statistically significantly positive effect on recipients' farm income, food security and women's empowerment. Though unusual, these positive results can be credited to the very low rate of loan repurposing and mostly to the lender's rigorous loan implementation strategy.Practical implicationsThe study results validate the hypothesis underlying development strategies that target women regarding loan programs. The study provides a simple yet valuable lesson for future credit impact evaluations: the context of the loan program as well as the evaluation indicators is essential.Social implicationsThis study’s findings suggest that microcredit, when offered judiciously and with support, can improve farmers' conditions.Originality/valueGiven the relatively long period studied, the analysis has been innovative in defining loan treatment and creating reliable treatment groups. Also to the best of the authors’ knowledge, this study is the first of its kind in Benin.
Photovoltaic thermal building skin: effect of condensing and evaporating temperature on flow rate and heat transfer
Authors: Riaz Ahmad , Zhou Chao , Liang Ruobing , Zhang Jili 
Published: December 2020

Purpose
This paper aims to present a numerical study on the natural convection, which operates either as an evaporator or condenser unit of the heat pump system to pre-cool and pre-heat the ambient fresh air.

Design/methodology/approach
This study focuses on natural air cooling or heating within the air channel considering the double skin configuration. Particular focus is given to the analysis of airflow and the heat transfer processes in an air channel to cool or heat the ambient fresh air. In this study, the physical model consists of one wall, either heated uniformly or cooled uniformly, whereas the other wall is adiabatic.

Findings
The results show that the variation of both velocity and temperature is observed as the flow transition occurs at the evaporator or condenser wall. In either case, the temperature rises in the range of 6.3–8.4°C with an increase in mass flow rate from 0.07–0.08 kg/s in the photovoltaic thermal condenser part, while in the photovoltaic thermal evaporator part, the change in mass flow rate from 0.048–0.061 kg/s causes a decrease in temperature from 7.1–4.5°C.

Practical implications
The solar-assisted photovoltaic thermal heat pump system, in building façade having an air layer application, is feasible for pre-heating and pre-cooling the ambient fresh air and also reduces the energy needed to treat the fresh air.

Originality/value
The influence of condensing and evaporating temperature under natural convection mode in double skin conformation is considered for pre-heating and pre-cooling of ambient fresh air.
Query processing over secure perturbed data over hybrid cloud
Authors: Vulapula Sridhar Reddy , Malladi Srinivas 
Published: December 2020

PurposeHybrid cloud composing of public and private cloud is seen as a solution for storage of health care data characterized by many private and sensitive data. In many hybrid cloud-based solutions, the data are perturbed and kept in public cloud, and the perturbation credentials are kept in private cloud.Design/methodology/approachHybrid cloud is a model combing private and public cloud. Security for the data is enforced using this distribution in hybrid clouds. However, these mechanisms are not efficient for range query and retrieval of data from cloud. In this work, a secure and efficient retrieval solution combining K-mean clustering, geometric perturbation and R-Tree indexing is proposed for hybrid clouds.FindingsCompared to existing solution, the proposed indexing on perturbed data is able to achieve 33% reduced retrieval time. The security of indexes as measured using variance of differences was 66% more than existing solutions.Originality/valueThis study is an attempt for efficient retrieval of data with range queries using R-Tree indexing approach.
Local meaning-making in discursive, embodied and affective registers
Authors: Pors Justine Grønbæk 
Published: December 2020

PurposeThe purpose of this paper is to argue and explore how local meaning-making processes of leaders also occur in embodied and affective registers. The paper aims to introduce the theoretical concept of affect to studies of local public leadership.Design/methodology/approachThe paper reports from an ethnographic study of local leaders managing educational institutions in Denmark. The paper takes a constructivist or interpretive approach where it is acknowledged that data is not just out-there ready to be collected and reported but is constructed and interpreted in particular manners as part of the complex encounter between researcher and field.FindingsThe paper zooms in one particular instance where a leader breaks down in tears and where the tears seem to evoke a particular affective atmosphere. Thus, the paper shows how, just below the elite narrative of a need for stronger, individual and more evidence-based management, we find a myriad of meaning-making processes that transgress distinctions between the corporeal, affective and discursive.Research limitations/implicationsAs an ethnography conducted in a local setting, the paper avoids broad generalisations. The findings reflect the theoretical ambition of discussing the role of embodiment and affect in local leadership as much as the studied setting.Practical implicationsThe study testify to how policy implementation can take many unexpected turns as local leaders interpret and make sense of policy ambitions in many different ways. Moreover, it testifies to how leaders are informed by embodied experiences and affective atmospheres in their sense-making processes.Originality/valueThe paper is one of the first attempts in public leadership to discuss the role of embodiment and affect in local public leadership.
An analysis of factors influencing omnichannel retailing adoption using ISM-DEMATEL approach: an Indian perspective
Authors: Mishra Ruchi 
Published: December 2020

PurposeThe study aims to identify and analyse complex interrelationships among factors influencing omnichannel retailing adoption in Indian apparel firms.Design/methodology/approachThe study applies an integrated interpretive structural modelling (ISM) and decision-making trial and evaluation laboratory (DEMATEL) approach for understanding the hierarchical and contextual relationship structure among the factors influencing omnichannel retailing adoption.FindingsThe integrated ISM–DEMATEL approach identifies that financial commitment is the most crucial factors followed by technological capability, training and development, performance metrics, supportive organisational structure, collaboration and knowledge sharing, offline–online information aggregation and integrated technological platform. Also, the study reveals that financial commitment and supportive organisational structure impact the majority of factors but are affected by only a few factors.Research limitations/implicationsUnlike previous studies, this study suggests an alternate approach to theory building emerging from the various factors that could be considered while developing omnichannel retailing.Practical implicationsPractitioners should pay close attention to leading factors that influence the adoption of omnichannel retailing, namely, financial commitments, supportive organisational structure, technological capability, integrated technological platform and training and development rather than focusing on significant receivers, such as warehouse management and assortment management.Originality/valueThe integrated approach of ISM-DEMATEL offers a hierarchical model and cause–effect relationship among factors influencing omnichannel retailing adoption.
Active fault-tolerant control of rotation angle sensor in steer-by-wire system based on multi-objective constraint fault estimator
Authors: Yang Qinjie , Shen Guozhe , Liu Chao , Wang Zheng , Zheng Kai , Zheng Rencheng 
Published: December 2020

Purpose
Steer-by-wire (SBW) system mainly relies on sensors, controllers and motors to replace the traditionally mechanical transmission mechanism to realize steering functions. However, the sensors in the SBW system are particularly vulnerable to external influences, which can cause systemic faults, leading to poor steering performance and even system instability. Therefore, this paper aims to adopt a fault-tolerant control method to solve the safety problem of the SBW system caused by sensors failure.

Design/methodology/approach
This paper proposes an active fault-tolerant control framework to deal with sensors failure in the SBW system by hierarchically introducing fault observer, fault estimator, fault reconstructor. Firstly, the fault observer is used to obtain the observation output of the SBW system and then obtain the residual between the observation output and the SBW system output. And then judge whether the SBW system fails according to the residual. Secondly, dependent on the residual obtained by the fault observer, a fault estimator is designed using bounded real lemma and regional pole configuration to estimate the amplitude and time-varying characteristics of the faulty sensor. Eventually, a fault reconstructor is designed based on the estimation value of sensors fault obtained by the fault estimator and SBW system output to tolerate the faulty sensor.

Findings
The numerical analysis shows that the fault observer can be rapidly activated to detect the fault while the sensors fault occurs. Moreover, the estimation accuracy of the fault estimator can reach to 98%, and the fault reconstructor can make the faulty SBW system to retain the steering characteristics, comparing to those of the fault-free SBW system. In addition, it was verified for the feasibility and effectiveness of the proposed control framework.

Research limitations/implications
As the SBW fault diagnosis and fault-tolerant control in this paper only carry out numerical simulation research on sensors faults in matrix and laboratory/Simulink, the subsequent hardware in the loop test is needed for further verification.

Originality/value
Aiming at the SBW system with parameter perturbation and sensors failure, this paper proposes an active fault-tolerant control framework, which integrates fault observer, fault estimator and fault reconstructor so that the steering performance of SBW system with sensors faults is basically consistent with that of the fault-free SBW system.
An epidemic model to address the spread of plant pests. The case of Xylella fastidiosa in almond trees
Authors: Signes-Pont María Teresa , Cortés-Plana José Juan , Mora Higinio , Mollá-Sirvent Rafael 
Published: December 2020

Purpose
The purpose of this paper is to present a discrete compartmental susceptible-asymptomatic-infected-dead (SAID) model to address the expansion of plant pests. The authors examined the case of Xylella fastidiosa in almond trees in the province of Alicante (Spain) to define the best eradication/contention protocol depending on the environmental parameters such as climatic factors, distance between trees, isolation of the plots, etc.

Design/methodology/approach
This approach considers the expansion of the disease among the almond trees orchards by means of a grid model. The cells of the grid represent a tree (or even a group of trees) that can be susceptible (healthy), asymptomatic (infected by the bacterium but without symptoms), infected or dead. When time passes, the status of the cells is determined by binary rules that update following both a neighborhood and a delay pattern. The model assumes that the environmental parameters have a crucial impact on the expansion of the disease, so a grid is assigned to each parameter to model the single effect caused by this parameter. The expansion is then the weighted sum of all the grids.

Findings
This proposal shows how the grid architecture, along with an update rule and a neighborhood pattern, is a valuable tool to model the pest expansion. This model has already been analyzed in previous works and has been compared with the corresponding continuous models solved by ordinary differential equations, coming to find the homologous parameters between both approaches. Thus, it has been possible to prove that the combination neighborhood-update rule is responsible for the rate of expansion and recovering/death of the illness. The delays (between susceptible and asymptomatic, asymptomatic and infected, infected and recovered/dead) may have a crucial impact on both the peak of infected and the recovery/death rate. This theoretical model has been successfully tested in the case of the dissemination of information through mobile social networks and is also currently under study in the case of expansion of COVID-19.

Originality/value
This work develops a new approach for the analysis of expansion of plant pests. This approach provides both behavioral variability at the cell level (by its capability to modify the neighborhood and/or the update rule and/or the delays) and modularity (by easy scaling the number of grids). This provides a wide range of possibilities to deal with realistic scenarios.
A systematic literature review for industry 4.0 maturity modeling: state-of-the-art and future challenges
Authors: Elibal Kerem , Özceylan Eren 
Published: December 2020

Purpose
The purpose of this paper is to conduct a systematic literature review for industry 4.0 maturity modeling research studies to obtain a clear view of the current state-of-the-art. Identifying characteristics of the studies; gaps, limitations and highlighted features has been aimed to guide future research studies.

Design/methodology/approach
The study includes a systematic literature review conducted on Scopus, IEEE Xplore and Web of Science databases and 90 publications have been reviewed. A novel qualitative taxonomy has been constructed which aims to reduce the cognitive load of the readers.

Findings
While industry 4.0 maturity modeling is an emerging concept and taking researchers’ attraction, review studies are still in infancy. Current review papers are inadequate in getting a clear idea about the concept, especially from the perspective of guiding future researchers. By the conducted approach of classification conducted in this paper, it has been seen that there are some challenges for improving the industry 4.0 maturity modeling.

Research limitations/implications
Findings represented in this study can serve academicians and practitioners to develop and/or improve industry 4.0 maturity models.

Originality/value
The study includes a novel classification for the reviewed papers. Constructed taxonomy is among the first and tabular representations instead of prose analogy that aims to simplify the review of papers.
The project steering committee, project governance and trust: insights from a practical case study
Authors: Karlsen Jan Terje 
Published: December 2020

PurposeTrust in how projects are managed is important because leaders have the power to make decisions that impact project outcomes. Steering committees provide strategic direction and governance for projects and they support the project manager. The purpose of this paper is to study how steering committees contribute to governance and trust. More specifically, the aim is to explore, which steering committee features and governance mechanisms are important for building trust.Design/methodology/approachEmpirical data were collected using in-depth interviews. The studied case concerns the Norwegian Navy’s experience with a steering committee in the project of building new frigates.FindingsFindings show that the steering committee had a significant impact on governance and trust in the project. The identified governance mechanisms performed by the steering committee included: control and performance measurement, support, decision-making, relationship management, reporting, resource management, risk management and strategic focus.Research limitations/implicationsDespite the limitations of studying only a single case, the findings may provide general learning, as well as important practical information and experience to managers interested in the role of the project steering committee.Practical implicationsThe paper provides key managerial implications that project owners should take into account when organizing a steering committee. The analysis identifies composition, competence, authority, responsibility, commitment and continuity as steering committee features that contribute to building trust. Findings particularly highlight the choice to include external steering committee members to be successful.Originality/valueThis research extends the current understanding of how through different features and governance mechanisms a steering committee can build trust in the management of projects.
Understanding users’ and hosts’ motives to co-working space: Case of Kuala Lumpur, Malaysia
Authors: Tan Teck Hong , Lau Kelly 
Published: December 2020

PurposeThe purpose of this paper is to address the knowledge gap by analysing the motivations of driving both users and hosts to the co-working space in Kuala Lumpur, Malaysia as the motives of co-working space is related to how well that space supports their needs.Design/methodology/approachBy using a mixed-methods approach, users’ and hosts’ behaviours were studied through the survey and in-depth interview, where 60 users were interviewed, as well as six operators of co-working space and two real estate market experts.FindingsBased on the results, convenient location, open space layout and ambiance, shared facilities, membership costs, flexible leases and knowledge sharing are the main motives that drive users to the co-working space and these motives are significantly related to user satisfaction. The results also showed that the users’ motives for working in the co-working space differ mostly from hosts in terms of service attributes.Research limitations/implicationsThe co-working space is more than just an office alternative but is a service-oriented real estate business. By providing the appropriate combination of attributes to succeed financially, co-workspace providers can support most of their members’ tasks, which leads to member satisfaction.Originality/valueResearch on the co-working place is still inadequate, particularly in Malaysia. Greater knowledge of attributes that influence users’ and hosts’ responses could lead to a better understanding and prediction in determining their needs and preferences.
Comparison of vegetation patch dynamics after the eruptions of the volcano Mount Usu, northern Japan, in 1977–1978 and 2000, detected by imagery chronosequence
Authors: Végh Lea , Tsuyuzaki Shiro 
Published: December 2020

AbstractVegetation patch dynamics were analyzed to detect vegetation development patterns after eruptions on two sites (summit destroyed in 1977–1978, and a foothill, Konpira destroyed in 2000) on the volcano Mount Usu, in northern Japan. Aerial photos and satellite images taken in 2000, 2006, and 2014 were used to develop an imagery chronosequence of vegetation patch dynamics. Vegetation patches were identified by the Normalized Difference Vegetation Index (NDVI) for satellite images, and by the Normalized Green‐Red Difference Index (NGRDI) for aerial photos. We categorized the vegetation patch types based on whether the patches overlapped (touching) or not (isolated) with the future vegetation patches and whether their area increased (growing) or decreased (shrinking). Afterwards, patch dynamics were compared between the two sites through changes in patch types, dense vegetation, and patch growth with slope degree, elevation, and time. Isolated patches were established more at the summit and showed high mortality, while at Konpira most isolated patches survived until 2006 and merged into touching patches by 2014. Moreover, the vegetation density of patches was higher at Konpira than at the summit. Patch growth was associated with patch types at both sites. However, the time was more important for the patch dynamics at the summit, and the vegetation density affected the dynamics more at Konpira. Therefore, the two sites had different vegetation patch dynamics, which were related to the characteristics of topography and eruptions. In conclusion, the imagery chronosequence proposed in this study monitored patch dynamics well, and patches developed faster at Konpira.
Gender, Authority and the Image of Queenship in English and Scottish Ballads, 1553–1603
Authors: HYDE JENNI 
Published: December 2020

AbstractThis article uses contemporary ballads to show that dynastic right was of central importance to the popular view of the accessions of Mary I and Elizabeth I, as well as that of the foreign king James VI when he acceded to the English throne in 1603. It challenges our view of Tudor iconography by showing that although popular songs were not afraid to tackle the gender implications of queens regnant, the popular image of Elizabeth I was not centred on her femininity. The article compares the positive English view of Mary I's femininity with negative portrayals of Mary Queen of Scots in Scotland, while suggesting that the issue of femininity was not raised in ballads about Elizabeth I because her half‐sister had already normalised the idea of a woman on the throne.