bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co‐mast: Harmonized seed production data for woody plants across US long‐term research sites
Authors: Nigro Katherine M. , Barton Jessica H. , Macias Diana , Chaudhary V. Bala , Pearse Ian S. , Bell David M. , Chen Angel , Cleavitt Natalie L. , Crone Elizabeth E. , Greene David F. , Holland E. Penelope , Johnstone Jill F. , Koenig Walter D. , Lyon Nicholas J. , Miller Tom E. X. , Schulze Mark , Snell Rebecca S. , Zimmerman Jess K. , Knops Johannes M. H. , McNulty Stacy , Parmenter Robert R. , Winterstein Mark A. , Zlotin Roman I. , LaMontagne Jalene M. , Redmond Miranda D. 
Published: December 2024

AbstractPlants display a range of temporal patterns of inter‐annual reproduction, from relatively constant seed production to “mast seeding,” the synchronized and highly variable interannual seed production of plants within a population. Previous efforts have compiled global records of seed production in long‐lived plants to gain insight into seed production, forest and animal population dynamics, and the effects of global change on masting. Existing datasets focus on seed production dynamics at the population scale but are limited in their ability to examine community‐level mast seeding dynamics across different plant species at the continental scale. We harmonized decades of plant reproduction data for 141 woody plant species across nine Long‐Term Ecological Research (LTER) or long‐term ecological monitoring sites from a wide range of habitats across the United States. Plant reproduction data are reported annually between 1957 and 2021 and based on either seed traps or seed and/or cone counts on individual trees. A wide range of woody plant species including trees, shrubs, and lianas are represented within sites allowing for direct community‐level comparisons among species. We share code for filtering of data that enables the comparison of plot and individual tree data across sites. For each species, we compiled relevant life history attributes (e.g., seed mass, dispersal syndrome, seed longevity, sexual system) that may serve as important predictors of mast seeding in future analyses. To aid in phylogenetically informed analyses, we also share a phylogeny and phylogenetic distance matrix for all species in the dataset. These data can be used to investigate continent‐scale ecological properties of seed production, including individual and population variability, synchrony within and across species, and how these properties of seed production vary in relation to plant species traits and environmental conditions. In addition, these data can be used to assess how annual variability in seed production is associated with climate conditions and how that varies across populations, species, and regions. The dataset is released under a CC0 1.0 Universal public domain license.
Thermal Runaway Detection Method for Smart Electric Bicycle Charger
Authors: Ning Jing , Xiao Bing , Zhao Wenbin 
Published: December 2024

ABSTRACTA novel algorithm for thermal runaway detection embedded in the electric bicycle charging system is proposed. The battery's internal temperature is a key indicator to diagnose battery safety and monitor the charging state. First, the relationship between the battery's internal temperature and the impedance's phase shift is derived theoretically. Second, given that random interference in the charging current, the current area integration algorithm (CAIA) is presented to measure the phase shift, so the internal temperature is estimated. Third, the smart charging system for electric bicycles is presented and results are discussed. The results show that the phase shift increases with the internal temperature in the range of 200–600 Hz when the internal temperature is 20°C–35°C. When the internal temperature reaches 45°C, the phase shift decreases sharply with the internal temperature. Therefore, smart electric bicycle charger realizes thermal runaway detection of electric bicycle.
Ketogenic diet therapy for the treatment of pediatric epilepsy
Authors: Haridas Babitha , Testino Alexander , Kossoff Eric H. 
Published: December 2024

AbstractIn 1921, the classic ketogenic diet was created at the Mayo Clinic in Rochester, Minnesota to treat epilepsy in children and adults. Over a century later, it is a widely used, standard‐of‐care therapy for typically treatment‐resistant epilepsy worldwide. There are currently five versions of ketogenic diet therapy that can be started either in or out of the hospital setting. It is overall effective in approximately half of children started, usually within a few months. Established indications for ketogenic diet therapy exist, in which this treatment may potentially even be more advantageous than antiseizure medications. Some of these indications include Glut1 deficiency, pyruvate dehydrogenase deficiency, infantile epileptic spasms syndrome, epilepsy with myoclonic‐atonic seizures, and formula‐fed children. Although most children are also receiving antiseizure medications with ketogenic diet therapy, its use may lead to medication reduction or withdrawal in some cases, and improvement in cognition and quality of life. Supplements are begun when ketogenic diet therapy is initiated in order to prevent common side effects, including constipation, kidney stones, growth disturbance, and dyslipidemia. Typically, after 2 years in most children, ketogenic diet therapy is discontinued gradually.
Effectiveness of cross‐sector collaboration in strategy implementation and impact: Evaluation of the NSW Skin Cancer Prevention Strategy 2016–2022
Authors: Mercado Gabriela , Tupanceski Irina , Scott Nicola , Woolley Nikki , Jayakody Amanda , Reakes Kate , McGill Sarah , O'Brien Tracey 
Published: December 2024

AbstractIssues AddressedAustralia continues to have one of the highest rates of skin cancer in the world. In NSW, melanoma is the third most common cancer diagnosed. At least 95% of skin cancers are caused by overexposure to ultraviolet radiation (UVR) from the sun, making it a highly preventable cancer. The NSW Skin Cancer Prevention Strategy (the Strategy) aims to reduce overexposure to UVR through collaborative efforts across government and non‐government partners and the private sector. An evaluation was required to inform the Skin Cancer Prevention Strategy 2023–2030 development and implementation.MethodsThe Strategy was evaluated using a mixed‐methods approach, which included both process and outcome evaluation measures. Measures included population and campaign tracking surveys, administrative datasets, a document review of progress reports and meeting minutes, and semi‐structured interviews and workshops with stakeholders.ResultsThe evaluation outlined activities and achievements under each of the Strategy goals. Findings demonstrated improved understanding and awareness of sun protection policies and guidelines, improved access to adequate shade, increased measurability of shade availability and adequacy, and increased adoption of sun protection behaviours.ConclusionCross‐agency collaboration and commitment were a key strength of the Strategy. The continued prioritisation of settings (e.g. schools, workplaces, etc.) and populations outlined in the Strategy were supported by the evaluation's findings. Additional focus areas for the new Strategy were highlighted, including secondary prevention or early detection. Continued skin cancer prevention activities, including social marketing campaigns and public education programs, are essential to ensure the adoption of sun protection behaviours by priority populations.
Leaders Inflate Performance Ratings for Employees Who Use Robots to Augment Their Performance
Authors: He Guohua , Yam Kai Chi , Zhao Puchu , Dong Xiaowei , Zheng Lixun , Qin Xin 
Published: December 2024

ABSTRACTWith robot usage becoming increasingly prevalent in contemporary workplaces, a key task for supervisors is conducting performance ratings in the context of employee‐robot value co‐creation. In this research, we explore whether, how, and when employees' robot usage affects supervisors' performance ratings. Drawing upon attribution theory, we suggest that supervisors might overestimate the performance of employees who use robots at work. Across a pilot study, two experiments, and one field study, we find that employees' robot usage is positively associated with supervisors' illusory performance transference (i.e., supervisors' belief that robot–associated performance should be attributed to employees who use robots at work). In turn, this transference is positively associated with high performance ratings for the respective employees. Furthermore, the supervisor–perceived experience of robots (i.e., supervisors' perceptions that robots are able to feel emotions and sensations) weakens this indirect effect. We conclude by discussing the theoretical and practical implications of our findings and future directions.
Hysterectomy without oophorectomy as a risk factor for genitourinary syndrome of menopause
Authors: Zapata‐Caballero Carlos Agustín , Robellada‐Zárate Claudia Melina , López‐Díaz Ana Jimena , Arellano‐Eguiluz Arturo , del Barco Laura Guadalupe Escobar 
Published: December 2024

SynopsisHysterectomy without oophorectomy increases the risk of genitourinary syndrome of menopause (GSM) in postmenopausal women compared to those with intact uteri.
Dual‐coupling networks engineering of self‐assembled ferromagnetic microspheres with enhanced interfacial polarization and magnetic interaction for microwave absorption
Authors: Xu Chunyang , Xiong Xuhui , Du Yiqian , Lv Xiaowei , Wu Zhengchen , Luo Kaicheng , Qian Yuetong , Che Renchao 
Published: December 2024

AbstractThe simultaneous enhancement of magnetic and dielectric properties in nanomaterials is becoming increasingly important for achieving exceptional microwave absorption performance. However, the engineering strategies for modulating electromagnetic responses remain challenging, and the underlying magnetic‐dielectric loss mechanisms are not yet fully understood. In this study, we constructed novel dual‐coupling networks through the tightly packed Fe3O4@C spindles, which exhibit both dielectric and magnetic dissipation effects. During the spray‐drying process, vigorous self‐assembly facilitated the formation of hierarchical microspheres composed of nanoscale core‐shell ferromagnetic units. Numerous heterogeneous interfaces and abundant magnetic domains were produced in these microspheres. The integrated dielectric/magnetic coupling networks, formed by discontinuous carbon layers and closely arranged Fe3O4 spindles, contribute to strong absorption through intense interfacial polarization and magnetic interactions. The mechanisms behind both magnetic and dielectric losses are elucidated through Lorentz electron holography and micromagnetic simulations. Consequently, the hierarchical microspheres demonstrate excellent low‐frequency absorption performance, achieving an effective absorption bandwidth of 3.52 GHz, covering the entire C‐band from 4 to 8 GHz. This study reveals that dual‐coupling networks engineering is an effective strategy for synergistically enhancing electromagnetic responses and improving the absorption performance of magnetic nanomaterials.image
Multimodal Ultrasound Diagnosis of Congenital Renal Arteriovenous Malformation: A Case Report
Authors: Zhang Liye , Li Keyan , Wu Dudu , Wu Shengzheng 
Published: December 2024

ABSTRACTTraditionally, computed tomography angiography has been considered the gold standard for diagnosing renal arteriovenous malformation (AVM). Despite the sensitivity of ultrasound in detecting AVM through Doppler techniques, it often lacks the ability to provide detailed insights into the lesion. In this narrative, we present a case of unexplained hematuria accompanied by flank pain, which was conclusively diagnosed as congenital renal AVM via multimodal ultrasound. The pivotal contributions of color Doppler ultrasound and contrast‐enhanced ultrasound are that they are instrumental in enabling an early and markedly precise diagnostic pathway.
Direct imaging with multidimensional labelling and high‐content analysis allows quantitative categorization and characterizations of individual small extracellular vesicles and nanoparticles (sEVPs)
Authors: Sun Simou , Cox‐Vázquez Sarah J. , Cho Nam‐Joon , Bazan Guillermo C. , Groves Jay T. 
Published: December 2024

AbstractSmall extracellular vesicles and nanoparticles (sEVPs) are cell‐secreted entities with potential as diagnostic biomarkers and therapeutic vehicles. However, significant intrinsic sEVP heterogeneity impedes analysis and understanding of their composition and functions. We employ multidimensional fluorescent labelling on sEVPs, leveraging the robustness of a newly developed membrane probe—conjugated oligoelectrolytes (COEs), and conduct total internal reflection fluorescence (TIRF) microscopy on sEVP arrays. These arrays comprise single sEVPs anchored to a soft material functionalized surface with little bias. We then develop an enhanced algorithm for colocalization analysis of the multiple labels on individual sEVPs and perform deep profiling of particle content. We categorize sEVPs derived from the same cell type into seven distinct subpopulations—some vesicular whereas others non‐vesicular, and we demonstrate that sEVPs from four cell types exhibit quantitatively distinguishable subpopulation distributions. Furthermore, we gain insights into specific particle features within each subpopulation, including CD63 counts, relative particle size, relative concentration of cargoes, and correlations among different cargoes. This high‐content analysis reveals common cargo sorting features in sEVP subpopulations across different cell types and suggests new statistics within the sEVP inherent heterogeneity that could differentiate sEVPs from two types of cancer cells and two types of normal cells. Collectively, our study presents a robust single‐sEVP characterization platform, combining high‐content imaging with comprehensive analysis. This platform is poised to advance sEVP‐based theranostic assays and facilitate exploration into disease‐associated sEVP biogenesis and sEVP‐mediated intercellular communication.
Decreased Constraints of Wind Erosion on Soil Seed Bank and Vegetation With the Stabilization of Sand Dune in Northern China
Authors: Yang Hongling , Li Yulin , Su Yongzhong , Yao Bo , Zhan Jin , Gong Xiangwen , Wang Lilong 
Published: December 2024

ABSTRACTWhile various measures have been taken to combat desertification and stabilize sand dunes, the persistence of “far and active sand dune” in northern China remains a great challenge. This study aimed to identify the primary driving factors that contribute to the stabilization of sand dunes within the Horqin Sandy Land. Our research investigated the richness and density of soil seed bank, seedlings, and vegetation communities across different slope positions in both active and stabilized sand dunes. Our results indicated that sand dune stabilization led to a significant increase in soil carbon and nitrogen contents, with increments of 0.09 ± 0.02 and 0.005 ± 0.001 g kg−1, respectively. Compared with active sand dune, the soil clay content and silt content in stabilized dune showed an increased rate of 23.59% and 30.43%, respectively, while the proportion of soil sand decreased significantly. Additionally, variations in the richness and density of seedlings and vegetation were observed across different slope positions, with lower leeward slopes exhibiting the most favorable conditions, hosting 11.4 ± 0.3 species in richness and 142.1 ± 5.4/m2, 303.4 ± 25.9/m2, and 37.2 ± 0.8/m2 in density for soil seed banks, seedlings, and vegetation, respectively. The soil seed bank showed a great potential for the regeneration of pioneer and annual plant species, particularly Agriophyllum squarrosum. Notably, our findings indicated a reduction in the influence of soil wind erosion intensity on the seed bank and vegetation during the stabilization process, as reflected by a 12% reduction in standardized total effects (STE). Conversely, the effects of soil temperature (STE ranging from 0.07 to 0.22), soil moisture (STE of −0.97 in stabilized dunes), and soil nitrogen content (STE of 0.28 in stabilized dunes) became more pronounced. These results underscore the importance of initially deploying mechanical sand barriers to manage active sand dunes, followed by the strategic planting of pioneer species, especially on the leeward slopes, to effectively promote the stabilization of the dunes.
Phosphatidylethanolamines are the Main Lipid Class Altered in Red Blood Cells from Patients with VPS13A Disease/Chorea‐Acanthocytosis
Authors: Peikert Kevin , Spranger Adrian , Miltenberger‐Miltenyi Gabriel , Glaß Hannes , Falkenburger Björn , Klose Christian , Tyteca Donatienne , Hermann Andreas 
Published: December 2024

AbstractBackgroundVPS13A disease is an ultra‐rare disorder caused by loss of function mutations in VPS13A characterized by striatal degeneration and by red blood cell (RBC) acanthocytosis. VPS13A is a bridge‐like protein mediating lipid transfer at membrane contact sites.ObjectivesTo assess the lipid composition of patient‐derived RBCs.MethodsRBCs collected from 5 VPS13A disease patients and 12 control subjects were analyzed by mass spectrometry (lipidomics).ResultsWhile we found no significant differences in the overall lipid class level, alterations in certain species were detected: phosphatidylethanolamine species with both longer chain length and higher unsaturation were increased in VPS13A disease samples. Specific ceramide, phosphatidylcholine, and sphingomyelin species were also altered.ConclusionsThe presented alterations of particular lipid species in RBCs in VPS13A disease may contribute to (1) the understanding of acanthocyte formation, and (2) future biomarker identification. Lipid distribution seems to play a key role in the pathophysiology of VPS13A disease. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Addressing the Unmet Need in the Treatment of Poststroke Anxiety, Depression, and Apathy: A Systematic Review of Potential Therapeutic Options
Authors: Liang Yuanchen , Levi Christopher , Sachdev Perminder S. , Spratt Neil , Bajorek Beata 
Published: December 2024

ABSTRACTHalf of stroke patients experience depression, anxiety, and/or apathy, adversely impacting poststroke recovery. Yet management of these remains suboptimal. To identify the broad spectrum of therapeutic modalities investigated for post‐stroke mood disorders, and their characteristics, administration regimens, and clinical outcomes. A structured, PRISMA‐guided literature review identified studies exploring preventative or treatment options. Seventy‐one identified studies (N = 5748 patients) comprised 62 clinical trials, 4 case reports, and 4 protocols or published abstracts. Most focused on depression; relatively few addressed anxiety and/or apathy. Overall, the efficacy of most treatments remains unclear due to the diversity and small size of studies (mostly pilot studies) precluding comparison. Preventative modalities such as nortriptyline (6 studies) reduced the incidence of depression, noting high rates of effectiveness in smaller studies (92.3%, study N = 48) patients. For the treatment of diagnosed mood disorders (58 studies), conventional pharmacotherapies (e.g., fluoxetine) were most effective, reducing depression, anxiety and/or apathy in up to 95.8% of patients (study N = 60). Physiological interventions (e.g., repetitive Transcranial Magnetic Stimulation, rTMS) variably reduced depression/anxiety severity (in 20.8%–93.3% of patients) whilst complementary therapies (e.g., acupuncture) reduced depression/anxiety severity in 60.0%–92.4% of patients (study N = 60). Combination therapies (e.g., fluoxetine plus acupuncture or rTMS plus Deanixt) significantly reduced depression severity in 93.3% of patients (study N = 60). Within the limited evidence in poststroke mood disorders, conventional pharmacotherapies appear most effective for both prevention and treatment, whilst nonpharmacological strategies and CAMs show potential. No treatment can be fully recommended without more robust trials.
Microbubble enhanced ultrasound with low mechanical index promotes therapeutic angiogenesis in hind limb ischemia mouse model
Authors: Zhu Qiong , He Ying , Dong Xiao Xiao , Xu Yali , Zhang Yi , Liu Zheng 
Published: December 2024

AbstractBackgroundMicrobubble enhanced ultrasound (MEUS) can augment tissue perfusion by angiogenesis yet the best treatment ultrasound power in the initial ischemia period is uncertain.PurposeConsidering the mechanical index (MI) is the most commonly used parameter for regulating diagnostic ultrasound power, here, we explored the effects of MEUS mediated by different MI on perfusion and sought to characterize the angiogenesis in the early stage of ischemia.MethodsExperiments were conducted on hind limb ischemia mouse model (HLI) and MEUS was administrated in the first week every other day following induction of HLI for four times. MEUS was conducted with a modified diagnostic ultrasound in combination with a lipid microbubble at 3 MHz and 21 cycles employing MI 0.3 (0.8 MPa), 0.7 (1.32 MPa) and 1.3 (2.78 MPa), respectively. Semi‐quantitative visual score and blood perfusion quantitation by contrast‐enhanced ultrasound were performed before each treatment. Hematoxylin‐eosin staining and immunohistochemistry with CD31 were performed after four times treatment.ResultsThe results showed HLI mice in MI 0.3 mediated MEUS group longitudinally exhibited more blood perfusion in calf muscle and less visible necrosis compared to other experimental groups in the early stage. Additionally, diffused inflammatory cells with greater number of vessels in calf muscle were observed in MI 0.3 group.ConclusionsLow MI mediated MEUS had significantly greater effects on augmenting muscle blood perfusion and reducing necrosis in the initial period after HLI surgery. These effects are most likely mediated by angiogenesis stimulated by low MI mediated MEUS.
Biological Evaluation of LL‐37 Antimicrobial Peptide‐Loaded Biodegradable Barrier Membranes in Guided Bone Regeneration
Authors: Pinthonglor Putida , Jaimalai Thanapak , Daranarong Donraporn , Jenvoraphot Thannaphat , Pongsuwan Punyaporn , Suree Nuttee , Prangkio Panchika , Punyodom Winita , Chamusri Nutchapon , Boonsri Burin , Supanchart Chayarop 
Published: December 2024

ABSTRACTThis study aims to determine the in vitro and in vivo biocompatibility and the differences in LL‐37 releasing patterns of the PLC/Col/LL‐37 sustained releasing membrane and the rapid releasing Col/LL‐37 membrane for use as a barrier membrane in guided bone regeneration. On Days 3 and 7, the PLC/Col/LL‐37 membrane revealed generated osteoclasts, whereas the PLC/Col membrane indicated mature osteoclasts. PLC/Col/LL‐37 was non‐toxic to blood cells and inhibited human albumin adhesion to the surface. A microbial reduction was observed in the Col/LL‐37 membrane, while both PLC/Col/LL‐37 and Col/LL‐37 may have caused early phases of skin sensitization. In animal testing, PLC/Col/LL37 and Col/LL37 exhibited the same levels of inflammation as the control group at all time points, while the different releasing patterns of LL‐37 loaded on PLC/Col/LL‐37 and Col/LL‐37 membranes had no effect on inflammation resolution in rat models.