bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGEMBANGAN PRODUK KOPI HERBAL OLAHAN DESA INKLUSIF GUNA MENINGKATKAN KESEJAHTERAAN KAUM DISABILITAS DI DESA BEDALI LAWANG KABUPATEN MALANG
Authors: Irianto Mochamad Fariz , Setiyowati Supami Wahyu , Hidayah Shodiq Auludin Rafiqu 
Published: November 2020

ABSTRAKPengembangan produk kopi herbal merupakan bagian dari pemberdayaan masyarakat dalam bentuk kegiatan produktif yang bertujuan untuk melatih masyarakat disabilitas untuk menghasilkan produk kopi herbal yaitu kopi koerja yang diharapkan memberikan dampak pada peningkatan kesejahteraan masyarakat. Metode pelaksanaan yang dilakukan adalah dengan sosialisasi program, pengadaan mesin dan pengadaan bahan penunjang, pelatihan pengolahan produk kopi herbal, dan pelatihan pemasaran strategi produk. Kegiatan ini diikuti oleh kelompok sasaran yaitu masyarakat disabilitas yang tergabung dalam organisasi difabel Lingkar Sosial Omah Difabel dengan peserta sebanyak 10 orang. Pelatihan ini sangat dirasakan manfaatnya oleh para peserta pelatihan anggota disabilitas seperti kemudahan pengoperasian alat produksi, rebranding produk, dan peningkatan jaringan pemasaran produk. Kata kunci: kopi herbal; masyarakat disabilitas; desa inklusif. ABSTRACTThe development of herbal coffee products is part of community empowerment in the form of productive activities that aim to train people with disabilities to produce herbal coffee products namely koerja coffee which is expected to have an impact on improving people's well-being. The implementation method is by socializing the program, procurement of machinery and procurement of supporting materials, training in processing herbal coffee products, and marketing training of product strategies. This activity was attended by a target group, namely people with disabilities who belonged to the Omah Difabel Social Circle disability organization with 10 participants. This training is strongly felt by the participants of disability member training such as ease of operation of production tools, product rebranding, and improvement of product marketing network Keywords: herbal coffee; people with disabilities; inclusive villages.
POLICY IMPLEMENTATION FOR HIV/AIDS AND SEXUALLY TRANSMITTED INFECTIOUS DISEASE PROGRAMS IN THE FIRST LEVEL OF HEALTH FACILITY
Authors: Suparmi Suparmi , Hardjanti Triana Sri , Kurniasih Hesti 
Published: November 2020

The number of HIV/AIDS and Sexually Transmited Infectious Diseases (PIMS) incidence in Indonesia, especially in Central Java are growing every year. Provincial government set a regulation in controlling disease that refers to the HIV/ AIDS Control Program and PIMS in the First Level of Health Facilities by the Ministry of Health in 2016. It is hoped that this program can break the chain of HIV/AIDS and PIMS cases while at the same time making a generation that healthy and productive quality. The aim of this study was to determine the implementation of programs to control HIV/AIDS and PIMS in Banyumas regency. The design of this study was descriptive qualitative through in-depth interviews. The main informants were ten HIV Counseling and Testing (KTHIV) of Public Health Center, triangulation informants were People Living With HIV/AIDS (PLWHA)Â patients, Clinical Doctors, Head of Department of Health Services P2P. The data were collected by in-depth interview technique. In addition to the interview, a survey was also conducted with PLWHA. Processing and analysis of data were using taxonomic analysis. The implementation of HIV/AIDS control program policies has not been optimal in its implementation. The lack of optimal implementation of HIV/AIDS and PIMS prevention policies is due to several aspects, i.e. policy accuracy, implementation accuracy, target accuracy, environmental accuracy, and process accuracy. Increasing monitoring and evaluation related to a program's policies is needed. Morover, Â it is important to improve the quality of human resources and careful planning related to the control program.
Farmers’ Perception about Major Insect Pests of Cucurbits and Their Management
Authors: Tripathi Subina , Shah Kabita Kumari , Tiwari Injila , Shrestha Jiban 
Published: November 2020

A survey was undertaken in five Village Development Committees (VDCs) of Lamjung District, Nepal from June to August 2018 to investigate major insect pests and their management practices in cucurbits. A total of ninety-five cucurbit growers were selected and interviewed using semi-structured questionnaires. The study revealed that the major insect pests attacking cucurbits were fruit fly, red pumpkin beetle, aphid, whitefly, epilachna beetle, cucurbit sting bug, cutworm, and blister beetle. The majority of farmers responded that fruit fly was the most prevalent insect pest, followed by aphid and red pumpkin beetle. Most of the farmers used chemical methods, that includes biological, mechanical, and cultural techniques to control the insects. For the mechanical method, they used sex-pheromone traps i.e. cue-lure. Among botanical pesticides, Neem (Azadirachta indica), Malabar Nut (Justicia adhatoda), Chinaberry (Melia azedarch), Mugwort (Artemisia spp.) were used. Commonly used insecticides by farmers were Cypermethrin, Dimethoate, Malathion, and Endosulfan. The indiscriminate use of chemical pesticides resulted in pest resistance, resurgence, and sometimes outbreak of insect pests. Majority of farmers were using chemical methods to control pests. Apart from this, Integrated Pest Management (IPM) was also adopted for good agricultural practices (GAP) to prevent chemical hazards on human health and the environment. To control insect pests, trained farmers should be encouraged to follow the sanitation of fields and protection of natural enemies by avoiding the use of pesticides a long as possible.
Pre-Hospital Advanced Life Support Resuscitation Training: A Pilot of An Evidence-Based Curriculum
Authors: Reid David , Sim Moira , Beatty Shelley , Grantham Hugh , Gale Mike 
Published: November 2020

Introduction There is a broad evidence base to support advanced life support (ALS) education for healthcare professionals being structured, realistic and inclusive of a range of human factors. This paper outlines the results of a pilot ALS resuscitation course tailored for providers working in pre-hospital resource-limited settings. The focus on the pre-hospital ALS environment, team mix, techniques, skills and equipment are important because actions taken by pre-hospital healthcare professionals have a critical impact on the likelihood of patient survival. Methods A pre-hospital ALS course was piloted following research into the need for a course and development of a pre-hospital-specific curriculum, based on Australian Resuscitation Council (ARC) guidelines. There were 13 pilot courses run, involving 66 participants. Participants all worked in the pre-hospital environment and held qualifications ranging from a Certificate IV in Healthcare through to postgraduate paramedicine qualifications. The pre-hospital ALS course consisted of theory and practical elements, pre-reading and a pre- and post-course quiz. Feedback was sought from course participants and an expert panel was consulted on the findings. Results Participants and the Expert Panel indicated that a pre-hospital ALS course should follow current recommendations of the ARC and be delivered to persons with sufficient underpinning knowledge of ALS resuscitation. The course should include pre-reading on ALS protocols and a pre-test followed by one day of face-to-face teaching using equipment reflective of the pre-hospital environment. Scenarios should be relevant to the pre-hospital setting and involve varying numbers of responders. Participants should be assessed on a continual basis during the course. Conclusion To improve participant confidence in the delivery of ALS and maximise the likelihood of patient survival, pre-hospital ALS resuscitation education for pre-hospital providers should follow ARC guidelines, include pre-course reading and practical simulation that reflects participants’ day-to-day employment.
Avaliação da qualidade de vida, capacidade funcional e força da musculatura respiratória em pacientes com insuficiência cardí­aca
Authors: Scariot Fernanda Foureaux , Rodrigues Marí­lia Mendes , Souza Beatriz Grassmann Gomes , Lima Fernanda Cristina , Nunes Kelly Christina de Faria , Braga Lays Magalhães 
Published: November 2020

A insuficiência cardí­aca (IC) é uma sí­ndrome clí­nica, via final comum de diversas doenças cardí­acas. O estudo teve como objetivo avaliar a qualidade de vida, a capacidade funcional e a força muscular respiratória em pacientes com IC classe funcional I e II. Tratou-se de um estudo observacional transversal, com amostra composta por 20 indiví­duos com faixa etária entre 58 e 82 anos, em acompanhamento clí­nico no Centro Clí­nico de Especialidades Médicas de Patos de Minas. Após a realização dos testes, foi observado em relação í qualidade de vida que o domí­nio mais comprometido foi o de limitação por aspectos fí­sicos. Não houve limitação na capacidade funcional e na força muscular respiratória, devido aos indiví­duos realizarem acompanhamento fisioterapêutico. A IC gera um impacto negativo sobre a qualidade de vida e que a fisioterapia é indispensável no acompanhamento e prognóstico desta população.Palavras-chave: Fisioterapia, insuficiência cardí­aca, músculos respiratórios, qualidade de vida.
Association of the Pattern and Quality of Sleep with Consumption of Stimulant Beverages, Cigarette and Alcohol among Medical Students
Authors: Bogati Sunil , Singh Tulika , Paudel Sagar , Adhikari Baikuntha , Baral Dharanidhar 
Published: November 2020

Background: Sleep is important in maintenance of proper functioning of both mental and physical functions of human body. Studies have shown there is impact on the sleep parameters with the use of caffeine, cigarette and alcohol. As there is little availability of similar studies here in Nepal, we made an attempt to know the relation of consumption of such substances with the sleep quality and sleep parameters as per Pittsburgh Sleep Quality Index scale.
Methods: A cross sectional study was conducted among the undergraduate students at BP Koirala Institute of Health Sciences, Dharan. Students were asked to complete a self- administered questionnaire to give information about demographic variables and habit of consumption of caffeinated beverages, cigarette and alcohol. The Pittsburgh Sleep Quality Index was utilized after the permission from authority to evaluate sleep quality.
Results: Out of 350, almost half of the students (44.6%) had poor sleep quality. 40.8% students reported sleeping six hours or less per night and 10.1% used medications to sleep. 96% reported consuming caffeinated beverages, 20% consumed cigarettes and 38.3% consumed alcoholic beverages. There was significant association of poor sleep quality with the increased consumption caffeine, cigarette and alcohol (p<0.05).
Conclusions: Poor sleep is prevalent among the undergraduate students of B P Koirala Institute of Health Sciences and the consumption of caffeine, cigarette and alcohol is associated with increment in poor sleep quality among them.
Keywords: Caffeinated beverages; pittsburgh sleep quality index
EULER NÃO SABIA NADA DE MATEMÁTICA?
Authors: Luchetta Valéria Ostete Jannis , Santos João Ricardo Viola dos 
Published: November 2020

A Matemática do Matemático é o fundamento da Matemática do Professor de Matemática. O que sustenta a Matemática da sala de aula da Educação Básica é a Matemática do Matemático. Pois bem, neste artigo produzimos uma discussão a respeito dessa suposta condição de necessidade,muitas vezes de suficiência, que opera como uma ideia naturalizada nas discussões de formação de professores de matemática. Para isso, realizamos uma leitura plausível de alguns escritos de Euler e de modos como Educadores Matemáticos e Matemáticos falam a respeito da formação matemática dele. Tomando como referência o Modelo dos Campos Semânticos (MCS) produzimos (sendo produzidos) outras possibilidades para Licenciaturas em Matemática. Nossas principais considerações são nadireção de movimentarmo-nos com essa discussão que coloca em xeque conhecimentos matemáticos de Euler, e procura desdobrar efeitos que dela decorre, em construções de projetos políticos de formações matemáticas em Licenciaturas em matemática: sempre em processos, movimentos.
O USO DE TAREFAS EXPLORATÓRIAS NO ESTUDO DA TRIGONOMETRIA EM TRIÂNGULOS ESFÉRICOS RETÂNGULOS
Authors: Fonseca Jussara Aparecida da , Leivas José Carlos Pinto 
Published: November 2020

O presente trabalho tem por objetivo analisar como alunos de um curso de licenciatura em matemática verificam expressões da trigonometria em triângulos esféricos retângulos, a partir das razões trigonométricas da geometria plana, na realização de tarefas exploratórias. Para tanto, por meiode uma abordagem de pesquisa qualitativa, buscamos aporte no papel das tarefas exploratórias no ensino de matemática e pautamos nossa coleta de dados na produção escrita dos sujeitos, oriundas das resoluções de dez dessas tarefas. Como resultado da análise feita, constatamos que a maioria dos participantes não tiveram dificuldades na verificação de expressões que exploravam as razões trigonométricas em triângulos retângulos planos, obtidos a partir de construções sobre as faces do triedro associado ao triângulo esférico retângulo, bem como naquelas definidas a partir da permutação de elementos. Verificamos que as dificuldades apresentadas se relacionaram principalmente na determinação da tangente de um arco, que em diversas situações foi indicada de forma equivocada. Além disso, alguns alunos apresentaram dificuldades na dedução das fórmulas que dependiam de outras expressões, não conseguindo articular um resultado já verificado com aquele a ser confirmado.
USO PEDAGÓGICO DAS TECNOLOGIAS DA INFORMAÇÃO E COMUNICAÇÃO (TIC): FORMAÇÃO INICIAL E PERCEPÇÕES DE LICENCIANDOS EM MATEMÁTICA DA UNESPAR
Authors: Maciel Kayque Henrique , Cibotto Rosefran Adriano Gonçales , Ceolim Amauri Jersi 
Published: November 2020

No trabalho apresentado investigamos como os formandos de cursos de licenciatura em Matemática pela Universidade Estadual do Paraná (Unespar) se sentem sobre a preparação para trabalhar de forma didática com as Tecnologias da Informação e Comunicação (TIC) e a maneira com a qual esse conteúdo foi desenvolvido ao longo de sua formação. Para realizar a pesquisa, de caráterqualitativo, elaboramos um questionário aplicado aos futuros docentes delimitados e analisamos as ementas dos cursos o conteúdo que estava sendo trabalhado nas disciplinas de informática, a fim de estabelecermos relações com as falas dos acadêmicos. Para analisar as respostas, utilizamos a metodologia da Análise Textual Discursiva de Roque de Moraes. Constatamos que a universidade oferta cinco cursos de licenciatura em matemática, em diferentes campi, e todos possuem, ao menos, uma disciplina de cunho tecnológico. Em apenas um dos cursos a disciplina de informática não possui em sua ementa referência acerca de ensinar o uso didático das TIC. Obtivemos 19 respostas do questionário e destacamos que a maioria dos estudantes que cursaram disciplinas de tecnologias com caráter didático relataram que se sentem preparados para trabalhar com as TIC em sala de aula; já osalunos que não cursaram disciplinas com essa característica se consideram inaptos a utilizarem pedagogicamente as TIC. Esse resultado enfatiza a importância desse conhecimento pedagógico para os futuros docentes. Considerando os dados estudados, constatamos que os cursos não são homogêneos e existem pontos que podem ser aprimorados na formação de professores de matemática na perspectiva do uso pedagógico das TIC.
MODELAGEM MATEMÁTICA NA LICENCIATURA EM MATEMÁTICA: UM OLHAR SOBRE O TEXTO PRODUZIDO POR UM LICENCIANDO
Authors: Campos Amanda Caroline Fagundes , Sant’Ana Marilaine de Fraga 
Published: November 2020

Neste artigo analisamos o texto produzido por um licenciando em matemática, sobre especificidades de Modelagem Matemática, por meio de conceitos de Basil Bernstein e da relação entre tal texto e vivências desse estudante na licenciatura. Com texto, visto aqui como um conceito de Basil Bernstein, nos referimos a escolhas, justificativas e exemplos apresentados pelo licenciando emuma entrevista que tratou de especificidades de Modelagem Matemática. Observamos, na análise qualitativa do texto, a busca do entrevistado por responder “o que é?” e “pra que serve?” Modelagem Matemática e, três objetivos, elencados por ele, com relação a essa tendência. Observamos também dificuldades na diferenciação entre Modelagem Matemática e Etnomatemática. Evidenciamos as vivências no curso de Licenciatura em Matemática como superiores aos referenciais teóricos de Modelagem Matemática como influência para a construção do texto do estudante. Diante disso, sugerimos, para o referido curso, mais vivências, que propiciem a diferenciação entre tendências emEducação Matemática e, a elaboração, pelos licenciandos, de justificativas.
FORMAÇÃO INICIAL DE PROFESSORES DE MATEMÁTICA(S): UM OLHAR DECOLONIAL SOBRE AS MUDANÇAS DE PERSPECTIVAS DOS ESTUDANTES
Authors: Knopp Ivo da Silva , Giraldo Victor , Araujo Victor Hugo Quaglia de , Neto Cleber Dias da Costa 
Published: November 2020

Este trabalho busca investigar como são constituídas, no contexto do curso de Licenciatura em Matemática da Universidade Federal do Rio de Janeiro, as mudanças de concepções e de perspectivas dos licenciandos sobre o próprio curso e sobre a profissão docente. Para isso, analisamos os impactos do curso de Licenciatura em Matemática na formação para ensinar matemática(s) no Ensino Fundamental e Médio a partir da decolonialidade. Propusemos uma roda de conversa com os estudantes de Licenciatura para coletar e analisar os dados, seguindo um modelo de análise de vídeos etranscrições. Observamos que as mudanças de perspectiva ocorridas expõem questões discutidas por referenciais teóricos sobre formação de professores. As reflexões ocorridas durante a execução dos procedimentos metodológicos configuram-se em grandes contribuições para o desenvolvimento deste artigo, pois reforçam nosso entendimento de que a investigação sobre a formação de futuros professores de matemática(s) deve ser problematizada, significativa e decolonial.
Identification of Interleukin-9 Producing Immune Cells in Endometrial Carcinoma and Establishment of a Prognostic Nomogram
Authors: Tong Huan , Feng Hao , Hu Xiang , Wang Meng-fei , Song Yun-feng , Wen Xiao-li , Li Yi-ran , Wan Xiao-ping 
Published: November 2020

BackgroundInterleukin-9 (IL9) plays a critical role in immunity and the pathogenesis of endometrial cancer (EC), especially endometrioid EC (EEC). This study aimed to identify the IL9+ immune cell subsets and their pleiotropic functions and establish an optimized prognostic nomogram towards the promotion of personalized treatment of EEC.Methods1,417 EC patients were involved in the present study. 143 patients from the tertiary gynecology centers in Shanghai between 2013 and 2019 were recruited, and the study protocol was approved by the Institutional Review Board (IRB) of Shanghai First Maternity and Infant Hospital. The genomic data of the other 1,274 patients were extracted from the TCGA and the MSKCC datasets, respectively. Immune and stromal scores were calculated using the ESTIMATE R tool, and the tumor infiltration of immune cells was analyzed using the TIMER platform. Metascape and GEPIA datasets were used for bioinformatic analysis. P &lt; 0.05 was considered statistically significant. All statistical analyses were performed with GraphPad Prism and R studio.Results552 genes that were correlated with leukocyte infiltration, lymphocyte activation, and regulation of innate immune response were up-regulated in the high immune score group. More IL9+ cell infiltration was detected in the highly and moderately differentiated EC (p = 0.04). High IL9+ lymphocyte infiltration was related to a better overall survival (p = 0.0027). IL9 positive cell clusters included ILC2s, Vδ2 γδT cells, mast cells, macrophages, and Th9 cells. Parameters such as FIGO stage, IL9 score, Vδ2 + γδT cell infiltration, classification of differentiation, and diabetes mellitus were assigned a weighted number of points in the nomogram for a specific predicted 3-, 5- and 10-year overall survival (OS). IL9–IL9R axis played a vital role in EEC, IL9R positive cell subgroups were also identified, and the related function was analyzed in the present study. Additionally, PR (Progesterone Receptor, or PGR) expression was relevant to a higher density of IL9+ lymphocyte infiltration. However, PGRMC1 (Progesterone Receptor Membrane Component 1) was negatively relevant to IL9R (p = 4.26e-8).ConclusionWe observed a significant infiltration of IL9+ cells and the overrepresentation of IL-9R in tissue specimens of patients in EC cases. The nomogram incorporating the IL9 could accurately predict individualized survival probability in EEC. Additionally, this study not only established a prognostic nomogram but also assist in the firmer understanding of the relevance of the IL9-IL9R axis and IL9-producing cells in EC immunity.
Serum Metabolomic Profiling Reveals the Amelioration Effect of Methotrexate on Imiquimod-Induced Psoriasis in Mouse
Authors: Zong Jiaxin , Cheng Jieyi , Fu Yuanfeng , Song Jing , Pan Weisong , Yang Li , Zhang Ting , Zhou Mingmei 
Published: November 2020

Background:The imiquimod (IMQ)-induced psoriasis mouse model has been used as a model for pathogenic mechanism research, and methotrexate (MTX) is widely employed to treat various clinical manifestations of psoriasis. We explored the underlying pathogenesis of psoriasis and the treatment mechanism of the conventional drugs from the metabolic perspective of the psoriasis mouse model.Methods:Male BALB/c mice were smeared IMQ for 7 days to induce treatment-resistant psoriasis and intragastrically administered 1 mg/kg MTX. We evaluated inflammation of psoriasis-like lesions and therapeutic effects of MTX based on histological changes and immunohistochemistry. Based on gas chromatography-mass spectrometer detection of serum samples, a comprehensive metabolomics analysis was carried out to identify alterations of metabolites.Results:It was found that MTX ameliorated psoriatic lesions (representative erythema, scaling, and thickening) by inhibiting proliferation and differentiation of keratinocytes. Using multivariate statistical analysis to process metabolomics data, the results displayed alterations in serum metabolites among mice of the control group, IMQ group, and MTX group. Compared with group, psoriasis mice had the higher level of d-galactose and lower expression of myo-inositol, 9,12-octadecadienoic acid, and cholesterol. In contrast with the model set, serum levels of glycine, pyrrolidone carboxylic acid, d-galactose, and d-mannose were significantly decreased in the MTX group.Conclusion:The differential metabolites, reflecting the perturbation in the pathways of inositol phosphate metabolism; galactose metabolism; glyoxylate and dicarboxylate metabolism; glycine, serine, and threonine metabolism; and glutathione metabolism, may lead to the pathogenesis of psoriasis, and they are also related to the pharmacological treatment effect of MTX on psoriasis. This study established the foundation for further research on the mechanism and therapeutic targets of psoriasis.