bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiological Characterization of a Directed and Weighted Disease Network Using Data From a Cohort of One Million Patients: Network Analysis
Authors: Ko Kyungmin , Lee Chae Won , Nam Sangmin , Ahn Song Vogue , Bae Jung Ho , Ban Chi Yong , Yoo Jongman , Park Jungmin , Han Hyun Wook 
Published: January 2020

Background
In the past 20 years, various methods have been introduced to construct disease networks. However, established disease networks have not been clinically useful to date because of differences among demographic factors, as well as the temporal order and intensity among disease-disease associations.

Objective
This study sought to investigate the overall patterns of the associations among diseases; network properties, such as clustering, degree, and strength; and the relationship between the structure of disease networks and demographic factors.

Methods
We used National Health Insurance Service-National Sample Cohort (NHIS-NSC) data from the Republic of Korea, which included the time series insurance information of 1 million out of 50 million Korean (approximately 2%) patients obtained between 2002 and 2013. After setting the observation and outcome periods, we selected only 520 common Korean Classification of Disease, sixth revision codes that were the most prevalent diagnoses, making up approximately 80% of the cases, for statistical validity. Using these data, we constructed a directional and weighted temporal network that considered both demographic factors and network properties.

Results
Our disease network contained 294 nodes and 3085 edges, a relative risk value of more than 4, and a false discovery rate-adjusted P value of <.001. Interestingly, our network presented four large clusters. Analysis of the network topology revealed a stronger correlation between in-strength and out-strength than between in-degree and out-degree. Further, the mean age of each disease population was related to the position along the regression line of the out/in-strength plot. Conversely, clustering analysis suggested that our network boasted four large clusters with different sex, age, and disease categories.

Conclusions
We constructed a directional and weighted disease network visualizing demographic factors. Our proposed disease network model is expected to be a valuable tool for use by early clinical researchers seeking to explore the relationships among diseases in the future.
Continuous Monitoring of Vital Signs in the General Ward Using Wearable Devices: Randomized Controlled Trial
Authors: Weenk Mariska , Bredie Sebastian J , Koeneman Mats , Hesselink Gijs , van Goor Harry , van de Belt Tom H 
Published: January 2020

BackgroundWearable devices can be used for continuous patient monitoring in the general ward, increasing patient safety. Little is known about the experiences and expectations of patients and health care professionals regarding continuous monitoring with these devices.ObjectiveThis study aimed to identify positive and negative effects as well as barriers and facilitators for the use of two wearable devices: ViSi Mobile (VM) and HealthPatch (HP).MethodsIn this randomized controlled trial, 90 patients admitted to the internal medicine and surgical wards of a university hospital in the Netherlands were randomly assigned to continuous vital sign monitoring using VM or HP and a control group. Users’ experiences and expectations were addressed using semistructured interviews. Nurses, physician assistants, and medical doctors were also interviewed. Interviews were analyzed using thematic content analysis. Psychological distress was assessed using the State Trait Anxiety Inventory and the Pain Catastrophizing Scale. The System Usability Scale was used to assess the usability of both devices.ResultsA total of 60 patients, 20 nurses, 3 physician assistants, and 6 medical doctors were interviewed. We identified 47 positive and 30 negative effects and 19 facilitators and 36 barriers for the use of VM and HP. Frequently mentioned topics included earlier identification of clinical deterioration, increased feelings of safety, and VM lines and electrodes. No differences related to psychological distress and usability were found between randomization groups or devices.ConclusionsBoth devices were well received by most patients and health care professionals, and the majority of them encouraged the idea of monitoring vital signs continuously in the general ward. This comprehensive overview of barriers and facilitators of using wireless devices may serve as a guide for future researchers, developers, and health care institutions that consider implementing continuous monitoring in the ward.Trial RegistrationClinicaltrials.gov NCT02933307; http://clinicaltrials.gov/ct2/show/NCT02933307.
Low-Burden Mobile Monitoring, Intervention, and Real-Time Analysis Using the Wear-IT Framework: Example and Usability Study
Authors: Brick Timothy R , Mundie James , Weaver Jonathan , Fraleigh Robert , Oravecz Zita 
Published: January 2020

Background
Mobile health (mHealth) methods often rely on active input from participants, for example, in the form of self-report questionnaires delivered via web or smartphone, to measure health and behavioral indicators and deliver interventions in everyday life settings. For short-term studies or interventions, these techniques are deployed intensively, causing nontrivial participant burden. For cases where the goal is long-term maintenance, limited infrastructure exists to balance information needs with participant constraints. Yet, the increasing precision of passive sensors such as wearable physiology monitors, smartphone-based location history, and internet-of-things devices, in combination with statistical feature selection and adaptive interventions, have begun to make such things possible.

Objective
In this paper, we introduced Wear-IT, a smartphone app and cloud framework intended to begin addressing current limitations by allowing researchers to leverage commodity electronics and real-time decision making to optimize the amount of useful data collected while minimizing participant burden.

Methods
The Wear-IT framework uses real-time decision making to find more optimal tradeoffs between the utility of data collected and the burden placed on participants. Wear-IT integrates a variety of consumer-grade sensors and provides adaptive, personalized, and low-burden monitoring and intervention. Proof of concept examples are illustrated using artificial data. The results of qualitative interviews with users are provided.

Results
Participants provided positive feedback about the ease of use of studies conducted using the Wear-IT framework. Users expressed positivity about their overall experience with the framework and its utility for balancing burden and excitement about future studies that real-time processing will enable.

Conclusions
The Wear-IT framework uses a combination of passive monitoring, real-time processing, and adaptive assessment and intervention to provide a balance between high-quality data collection and low participant burden. The framework presents an opportunity to deploy adaptive assessment and intervention designs that use real-time processing and provides a platform to study and overcome the challenges of long-term mHealth intervention.
Evaluation of Spin in the Abstracts of Systematic Reviews and Meta-Analyses Focused on the Treatment of Acne Vulgaris: Cross-Sectional Analysis
Authors: Ottwell Ryan , Rogers Taylor C , Anderson J Michael , Johnson Austin , Vassar Matt 
Published: January 2020

Background
Spin is the misrepresentation of study findings, which may positively or negatively influence the reader’s interpretation of the results. Little is known regarding the prevalence of spin in abstracts of systematic reviews, specifically systematic reviews pertaining to the management and treatment of acne vulgaris.

Objective
The primary objective of this study was to characterize and determine the frequency of the most severe forms of spin in systematic review abstracts and to evaluate whether various study characteristics were associated with spin.

Methods
Using a cross-sectional study design, we searched PubMed and EMBASE for systematic reviews focusing on the management and treatment of acne vulgaris. Our search returned 316 studies, of which 36 were included in our final sample. To be included, each systematic review must have addressed either pharmacologic or nonpharmacologic treatment of acne vulgaris. These studies were screened, and data were extracted in duplicate by two blinded investigators. We analyzed systematic review abstracts for the nine most severe types of spin.

Results
Spin was present in 31% (11/36) of abstracts. A total of 12 examples of spin were identified in the 11 abstracts containing spin, with one abstract containing two instances of spin. The most common type of spin, selective reporting of or overemphasis on efficacy outcomes or analysis favoring the beneficial effect of the experimental intervention, was identified five times (5/12, 42%). A total of 44% (16/36) of studies did not report a risk of bias assessment. Of the 11 abstracts containing spin, six abstracts (55%) had not reported a risk of bias assessment or performed a risk of bias assessment but did not discuss it. Spin in abstracts was not significantly associated with a specific intervention type, funding source, or journal impact factor.

Conclusions
Spin is present in the abstracts of systematic reviews and meta-analyses covering the treatment of acne vulgaris. This paper raises awareness of spin in abstracts and emphasizes the importance of its recognition, which may lead to fewer incidences of spin in future studies.
Весовые неравенства для потенциала Данкля–Рисса
Authors: Горбачев Дмитрий Викторович , Иванов Валерий Иванович 
Published: January 2020

Для классического потенциала Рисса или дробного интеграла $$I_{\alpha}$$ хорошо известны условия Харди-Литлвуда-Соболева-Стейна-Вейса $$(L^p, L^q)$$ -ограниченности со степенными весами. С помощью преобразования Фурье $$\mathcal{F}$$ потенциал Рисса определяется равенством $$\mathcal{F}(I_{\alpha}f)(y)=|y|^{-\alpha}\mathcal{F}(f)(y)$$. Важным обобщением преобразования Фурье стало преобразование Данкля $$\mathcal{F}_k$$, действующее в лебеговых пространствах с весом Данкля, определяемым с помощью системы корней $$R\subset\mathbb{R}^d$$, ее группы отражений G и неотрицательной функции кратности k на R, инвариантной относительно G. С. Тангавелу и Ю. Шу с помощью равенства $$\mathcal{F}_k(I_{\alpha}f)(y)=|y|^{-\alpha}\mathcal{F}_k(f)(y)$$ определили D-потенциал Рисса. Для D-потенциала Рисса также были доказаны условия ограниченности в лебеговых пространствах с весом Данкля и степенными весами, аналогичные условиям для потенциала Рисса. На конференции "Follow-up Approximation Theory and Function Spaces" в Centre de Recerca Matem`atica (CRM, Barcelona, 2017) М.Л. Гольдман поставил вопрос об условиях $$(L_p,L_q)$$-ограниченности D-потенциала Рисса с кусочно-степенными весами. Рассмотрение кусочно-степенных весов позволяет выявить влияние на ограниченность D-потенциала Рисса поведения весов в нуле и бесконечности. В настоящей работе на этот вопрос дается полный ответ. В частности,в случае потенциала Рисса получены необходимые и достаточные условия. В качестве вспомогательных результатов доказаны необходимые и достаточные условия ограниченности операторов Харди и Беллмана в лебеговых пространствах с весом Данкля и кусочно-степенными весами.
ESTRATÉGIAS DE CONTROLE DAS CLASSES PERIGOSAS: O ENSINO PROFISSIONAL DO IMPÉRIO À REPÚBLICA
Authors: Afonso José António Martin Moreno , Santos Renato Marinho Brandão 
Published: January 2020

O artigo analisa as diferentes concepções politico-educativas sobre o ensino profissional no Brasil, desde os Liceus e Casas de Educandos, no período imperial, até as Escolas de Aprendizes, estabelecidas nas capitais brasileiras a partir de 1910, durante a Primeira República. Discute, ao longo dos diferentes períodos, a associação entre o ensino profissional e o controle das denominadas “classes perigosas”. Especificamente em relação à República, observa o diálogo entre esse regime, que procura se associar às ideias do novo e do progresso, e as Escolas enquanto instituições modernas responsáveis por estabelecer padrões de comportamento e valores. Em conclusão, afirma que os caminhos para consolidação do ensino profissional no Brasil foram tortuosos, tendo como reflexo, entre outros pontos, os altos índices de evasão verificados nas Escolas de Aprendizes.
Racial Ethnic Disparities in Youth With Type 1 Diabetes Participating in Diabetes Summer Camps
Authors: Valenzuela Jessica M. , Records Sam E. , Mueller Kelly A. , Martin Megan T. , Wolf Risa M. 
Published: January 2020

OBJECTIVE
Diabetes camps are beneficial for campers and include benefits such as increases in diabetes knowledge, glycemic control, and psychological functioning. Racial/ethnic minority youth are likely to have poorer disease management and glycemic control. We hypothesized that minority youth with type 1 diabetes have reduced participation in diabetes summer camps.

RESEARCH DESIGN AND METHODS
We analyzed deidentified data from 5,256 campers with type 1 diabetes who participated in a network of 48 American Diabetes Association–affiliated summer camps in 2018, and we compared participation rates by racial/ethnic category to the most recent SEARCH for Diabetes in Youth study prevalence rates.

RESULTS
Camper demographics were significantly different than in the general population of children with type 1 diabetes (P &lt; 0.001). Minority youth were more likely to attend day camp, be first-time campers, and request financial aid, and they were less likely to be on insulin pump therapy or use continuous glucose monitors.

CONCLUSIONS
Racial/ethnic minority youth with diabetes are underrepresented in diabetes camps nationwide.
Diabetic Neuropathy Is a Substantial Burden in People With Type 1 Diabetes and Is Strongly Associated With Socioeconomic Disadvantage: A Population-Representative Study From Scotland
Authors: Jeyam Anita , McGurnaghan Stuart J. , Blackbourn Luke A.K. , McKnight John M. , Green Fiona , Collier Andrew , McKeigue Paul M. , Colhoun Helen M. 
Published: January 2020

OBJECTIVE
To assess the contemporaneous prevalence of diabetic peripheral neuropathy (DPN) in people with type 1 diabetes (T1D) in Scotland and study its cross-sectional association with risk factors and other diabetic complications.

RESEARCH DESIGN AND METHODS
We analyzed data from a large representative sample of adults with T1D (N = 5,558). We assessed the presence of symptomatic neuropathy using the dichotomized (≥4) Michigan Neuropathy Screening Instrument Patient Questionnaire score. Logistic regression models were used to investigate associations between DPN and risk factors, as well as with other complications.

RESULTS
The burden of DPN is substantial with 13% prevalence overall. Adjusting for attained age, diabetes duration, and sex, the odds of DPN increased mainly with waist-to-hip ratio, lipids, poor glycemic control (odds ratio 1.51 [95% CI 1.21–1.89] for levels of 75 vs. 53 mmol/mol), ever versus never smoking (1.67 [1.37–2.03]), and worse renal function (1.96 [1.03–3.74] for estimated glomerular filtration rate levels &lt;30 vs. ≥90 mL/min/1.73 m2). The odds significantly decreased with higher HDL cholesterol (0.77 [0.66–0.89] per mmol/L). Living in more deprived areas was associated with DPN (2.17 [1.78–2.65]) for more versus less deprived areas adjusted for other risk factors. Finally, individuals with prevalent DPN were much more likely than others to have other diabetes complications.

CONCLUSIONS
Diabetic neuropathy remains substantial, particularly affecting those in the most socioeconomically deprived groups. Those with clinically manifest neuropathy also have a higher burden of other complications and elevated levels of modifiable risk factors. These data suggest that there is considerable scope to reduce neuropathy rates and narrow the socioeconomic differential by better risk factor control.
O papel do discurso religioso na construção da identidade etnocultural dos imigrantes italianos em Curitiba no final do século XIX
Authors: Machioski Fábio Luiz , Gonçalves Marcos 
Published: January 2020

No presente artigo, pretendemos discutir como, e por que, a religião conseguiu influenciar no processo de construção da identidade etnocultural dos imigrantes italianos que se instalaram na região de Curitiba no final do século XIX. Almejamos entender de que modo o discurso religioso foi útil para o forjar de um sentimento de pertencimento étnico entre os indivíduos desse grupo específico de estrangeiros que se fixou no entorno da capital paranaense. Com o intuito de encontrar respostas para esta questão, apresentamos algumas definições e ideias sobre religião e identidade elaboradas pelos sociólogos Peter Berger, Pierre Bourdieu e Denys Cuche, como também pelo filósofo Paul Valadier. Tais conceitos, como por exemplo o de poder simbólico e de habitus religioso, serviram para analisar o discurso do padre Pietro Colbacchini, sacerdote católico que organizou a prática religiosa dos imigrantes italianos em Curitiba, e assim compreender a relevância que a religião assumiu junto ao referido processo de identificação sociocultural.
Gênero e neopentecostalismo: um olhar a partir do projeto Godllywood
Authors: Oliveira Alesca Prado de , Enoque Alessandro Gomes 
Published: January 2020

É objeto do presente estudo desvelar a dinâmica das relações que são construídas a partir do sagrado para com o gênero e, para tanto, adentraremos no universo da Igreja Universal do Reino de Deus (IURD), através de seu projeto para as mulheres fiéis, denominado Godllywood. Por meio de pesquisa teórica sobre a produção científica que aborda a inter-relação gênero e religião, e de pesquisa documental no canal virtual do projeto, coletamos informações sobre os desafios lançados pela líder iurdiana às suas leitoras. A dicotomia estabelecida entre o tradicionalismo evangélico e a aceitação dos novos valores da sociedade se exemplifica no projeto apresentado.
A fé dos jornalistas e as práticas religiosas no Brasil
Authors: Mick Jacques , Furtado Kevin Willian Kossar 
Published: January 2020

O artigo compara os dados disponíveis sobre as religiões dos jornalistas brasileiros com as características gerais da religiosidade da população a partir dos dados presentes no Perfil do jornalista brasileiro, de 2012, e no censo de 2010 do Instituto Brasileiro de Geografia e Estatística (IBGE). O objetivo é compreender se as particularidades da experiência religiosa entre os jornalistas podem ter efeitos na cobertura do tema, algo que é relevante diante das consequências sociopolíticas e econômicas das mudanças recentes na religiosidade no país. Os dados indicam três diferenças marcantes entre os jornalistas: a) presença mais significativa de não praticantes e ateus; b) participação significativamente menor de católicos e evangélicos; e c) maior expressividade de espíritas e praticantes de religiões de origem africana. O texto suscita a hipótese de que essas diferenças, junto a outros fatores, podem explicar fenômenos como a relativa desatenção da cobertura jornalística ao crescimento da população neopentecostal no país e as abordagens em geral positivas que o espiritismo recebia da mídia.
Fronteiras eclesiais no pontificado de Francisco
Authors: Wolff Elias , Colet Raquel De Fátima 
Published: January 2020

Para bem compreender o pontificado de Francisco, é preciso analisar os percursos fronteiriços pelos quais ele transita. O objetivo deste artigo é mostrar o papa Francisco como um homem de fronteiras, que as reconhece em seu valor eclesial, mas também em muito as amplia ou supera. O método utilizado é o da análise qualitativa da bibliografia que mostra o posicionamento do papa nas questões de fronteiras na igreja. O resultado é a apresentação de um diagnóstico das atuais fronteiras doutrinais e estruturais do catolicismo e suas implicações para uma igreja em “estado permanente de missão”. Mostra como o papa Francisco faz o discernimento das fronteiras que se justificam evangelicamente na igreja e aponta para a superação daquelas que não se legitimam na proposta de uma “igreja em saída”, por um processo de reformas como permanente conversão pastoral.
Sobre la historia y contenidos del manuscrito Vaticano Ross. 350
Authors: Cancela Cilleruelo Álvaro 
Published: January 2020

El presente artículo aborda la historia y los contenidos el códice Città del Vaticano, Biblioteca Apostolica Vaticana, Ross. 350 (s. XV). Por un lado, se restituye una nota de posesión perdida de la abadía de Florencia mediante el uso de luz ultravioleta y el cotejo de ex libris similares. Sus contenidos, relacionados con el códice Paris, Bibliothèque Nationale de France, lat. 2997, podrían secundar un origen alemán, propuesto sobre base iconográfica. Se ofrece la identificación del único texto desconocido del manuscrito: un fragmento del Liber de compunctione cordis de Efrén Sirio, traducido del griego en época tardoantigua. Su estudio permite deducir que el códice fue comisionado por un eclesiástico seglar desconocido que intervino activamente en el texto.
Porosity Distribution and Differentiation of Different Types of Fluids in Reservoir of Sawan Gas Field, Lower Indus Basin, Pakistan
Authors: Asad M. , Rahim H.U. 
Published: January 2020

Abstract
The lower Indus basin is one of the prolific basins in Pakistan in which the C-interval of lower Goru formation act as a reservoir. With the help of petrophysical interpretation production zone is recognized and also porosity is calculated at the reservoir level. Through porosity we are able to calculate Ksat. A model based inversion of 2D seismic inversion was performed to ascertain three dimensional dispersion of acoustic impedance in the investigation zone and we have recognized new areas where porosity distribution is maximum and site which is suitable for new well. Porosity and Acoustic impedance are typically contrarily relative to each other. Presently porosity can be anticipated in seismic reservoir characterization by utilizing acoustic impedance from seismic inversion far from well position.
Aktivitas Penyembuhan Luka Insisi dari Salep Daun Binahong (Anredera scandens (L.) Moq.)
Authors: Wilantari Putu Dessy 
Published: January 2020

Luka insisi adalah luka yang terjadi karena teriris oleh instrumen yang tajam, misalnya luka yang terjadi setelah pembedahan atau operasi. Penelitian ini dilakukan untuk mengetahui aktivitas sediaan salep ekstrak daun A. scandens (L.) Moq. pada penyembuhan luka insisi. Parameter standardisasi ekstrak meliputi kadar air, kadar abu total, kadar abu tidak larut asam, dan kadar flavonoid total. Pengujian aktivitas sediaan salep ekstrak daun A. scandens (L.) Moq. dilakukan pada tiga puluh lima ekor tikus betina galur Wistar. Pengamatan dilakukan secara makroskopis pada hari ke-0, 7, 14 dan 21 terhadap adanya eritema, edema, dan keropeng, serta pengamatan mikroskopis pada hari ke-21 melihat adanya infiltrasi sel radang dan pembentukan kolagen. Hasil pengamatan makroskopis menunjukkan adanya penurunan tanda eritema dan edema, namun tidak berbeda bermakna secara statistik pada semua kelompok perlakuan (K2, K3, K4, K5, K6, dan K7) (p>0,05) dan keropeng yang menurun dimulai dari hari ke-7. Berdasarkan hasil yang diperoleh, menunjukkan bahwa pemberian sediaan salep ekstrak daun A. scandens (L.) Moq. berpotensi dalam penyembuhan luka insisi yang diamati secara makroskopis.