bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate change impacts on summer flood frequencies in two mountainous catchments in China and Switzerland
Authors: Ragettli S. , Tong X. , Zhang G. , Wang H. , Zhang P. , Stähli M. 
Published: December 2019

Abstract
Flood events are difficult to characterize if available observation records are shorter than the recurrence intervals, and the non-stationarity of the climate adds additional uncertainty. In this study, we use a hydrological model coupled with a stochastic weather generator to simulate the summer flood regime in two mountainous catchments located in China and Switzerland. The models are set up with hourly data from only 10–20 years of observations but are successfully validated against 30–40-year long records of flood frequencies and magnitudes. To assess the climate change impacts on flood frequencies, we re-calibrate the weather generator with the climate statistics for 2021–2050 obtained from ensembles of bias-corrected regional climate models. Across all assessed return periods (10–100 years) and two emission scenarios, nearly all model chains indicate an intensification of flood extremes. According to the ensemble averages, the potential flood magnitudes increase by more than 30% in both catchments. The unambiguousness of the results is remarkable and can be explained by three factors rarely combined in previous studies: reduced statistical uncertainty due to a stochastic modelling approach, hourly time steps and the focus on headwater catchments where local topography and convective storms are causing runoff extremes within a confined area.
An analysis of unmet water demand under climate change scenarios in the Gualí River Basin, Colombia, through the implementation of Hydro-BID and WEAP hydrological modeling tools
Authors: Mena Darwin , Solera Abel , Restrepo Lina , Pimiento Melissa , Cañón Miguel , Duarte Freddy 
Published: December 2019

Abstract
Climate change can affect hydrological services in Andean basins, so a possible reduction in water supply can lead to not meeting the needs of different users, which has become a real challenge for decision-makers with regards to water management. This paper presents the results obtained from hydrological modeling exercises in the Gualí River Basin (Colombia) by combining the Hydro-BID modeling tool, which consists of an analytical hydrology database for Latin America and the Caribbean that provides a great advantage for countries with limited information and the Water Evaluation and Planning System (WEAP) modeling tool, in order to determine the potential impacts of climate change on unsatisfied demand for water in the basin. The results show a possible decrease in flow compared to current conditions; between 5.8% and 9.56% for CPR 2.6, and between 2.18% and 6.86% for CPR 8.5. The approach presented is useful to ensure that timely decisions are made to meet the demands of users under the conditions of climate change.
Long-Term Effects of Hypoxia-Reoxygenation on Thioredoxins in Rat Central Nervous System
Authors: Otero-Losada Matilde , L Canepa , Udovin Lucas , Kobiec Tamara , Toro-Urrego Nicolás , A. Kölliker-Frers Rodolfo , Capani Francisco 
Published: December 2019

Background:Oxidative stress induced by the oxidative pathway dysregulation following ischemia/ reperfusion has been proposed as an important cause of neuronal death and brain damage. The proteins of the thioredoxin (Trx) family are crucial mediators of protein function regulating the intracellular hydrogen peroxide levels and redox-sensitive post-translational protein changes.Aim:To analyze the expression and distribution of fourteen members of the Trx family, potentially essential for the regeneration upon long-term brain damage, in a perinatal hypoxia-ischemia rat model induced by common carotid artery ligation.Methods:The right common carotid artery (CCA) was exposed by an incision on the right side of the neck, isolated from nerve and vein, and permanently ligated. Sham-surgery rats underwent right CCA surgical exposure but no ligation. Euthanasia was administered to all rats at 30, 60, and 90 days of age. Protein expression and distribution of fourteen members of the Trx family and related proteins (Grx1, Grx2, Grx3, Grx5, Prx1, Prx2, Prx3, Prx4, Prx5, Prx6, Trx1, Trx2, TrxR1, TrxR2) was examined in the most hypoxia susceptible rat brain areas, namely, cerebellum, corpus striatum, and the hippocampus.Results:The thioredoxin proteins displayed a complex, cell-type, and tissue-specific expression pattern following ischemia/reperfusion. Even 60 days after ischemia/reperfusion, Western blot analysis showed a persistent expression of Trx1 and Grx2 in several brain areas.Conclusion:The Trx family of proteins might contribute to long-term survival and recovery supporting their therapeutic use to curtail ischemic brain oxidative damage following an ischemia/reperfusion insult. Characterization of ischemia/reperfusion oxidative brain damage and analysis of the involved mechanisms are required to understand the underneath processes triggered by ischemia/reperfusion and to what extent and in what way thioredoxins contribute to recovery from brain hypoxic stress.
High Frequency of the Opioid Receptor µ-1 (OPRM1) A118G Polymorphism, an Opioid Drug Therapy Related Gene, in the Indonesian Population
Authors: Puspitasari Alvina Arum , Ikawati Zullies , Swasthikawati Sri , Rahmawati Anindya 
Published: December 2019

Background:
The opioid receptor μ-1 (OPRM1) has become one of the most
studied genes in pharmacogenetics, as this gene encodes the μ-opioid receptor (MOR),
which plays a role in opioid drugs response, as well as in various disorders. One of its
variants, A118G, which is found at a high frequency in the Asian population, has been associated
with loss of sensitivity to and an increased requirement for analgesics in the
treatment of pain, increased pain sensitivity, various types of substance dependencies, and
the development of breast cancer. However, there are still limited reports about this gene
polymorphism in the Indonesian population.

Objective:
The study aimed to determine the allele frequencies of the OPRM1 A118G
polymorphism among the Indonesian population.

Method:
A cross-sectional study of 158 subjects, comprising 79 males and 79 females,
was conducted among Indonesians, and genotype analysis was carried out by a modified
allele-specific Polymerase Chain Reaction (PCR) method.

Results:
A frequency of 60.4% was found for the G allele among Indonesian samples,
with a higher frequency being present in males (66.5%). The A allele was found at frequencies
of 33.5% and 45.6% in males and females, respectively. A significant difference
in allele frequency was found between males and females (p = 0.029, OR = 1.659, 95% CI
[1.052–2.614]), while there was no significant difference in genotype frequencies between
groups.

Conclusion:
A high prevalence of the OPRM1 A118G polymorphism was found in the
Indonesian population, with the G allele frequency tending to be higher in males.
A Collaborative Edge-Cloud Internet of Things Based Framework for Securing the Indian Healthcare System
Authors: Zahra Syed Rameem , Chishti Mohammad Ahsan 
Published: December 2019

:
Today, 73 years after the independence and twenty years after the turn of the century,
“Health for All” which should have been accomplished by now, remains a far-fetched and an elusive
dream. Instead, the people of India are bequeathed a triple burden of disease: sustaining the
weight of transmittable infections, expanding burden of nontransferable illnesses, and a healthcare
system not efficient enough to handle them both. At present, India is home to one-third of the poor
population around the world. After a high population growth rate, unregulated and inefficient
healthcare is the major cause for this abjection and poverty. The global position of India vis-à-vis
the health indicators like Infant Mortality Rate (IMR), Crude Birth Rate (CBR), Crude Death Rate
(CDR) and life expectancy is shocking, shameful and on a downward trend. The objective of this
paper was to identify the major issues in the Indian healthcare system and offer Internet of Things
(IoT) based solutions. The underdevelopment of health and health services in India is brought
about by the same determinants that cause underdevelopment in the first place. This paper discusses
these causes and major issues responsible for the dilapidated state of Indian healthcare and
offers IoT based solutions for dealing with each of these issues. Moreover, a collaborative
edge/cloud IoT based framework has been proposed for remedying the Indian healthcare.

:
The presented solutions could be used for making healthcare and thereby, health, a reality for
all.
Analysis of Performance of Two Wavelet Families Using GLCM Feature Extraction for Mammogram Classification of Breast Cancer
Authors: Singla Shivangi , Kumari Uma 
Published: December 2019

Background:
Mammogram images are low dose x-ray images which detect the breast
cancer before the women can actually experience it.

Objective:
To determine the accurate methodology for feature extraction using different wavelet
families and different classification algorithms.

Methods:
Two wavelet families are used namely Daubechies (db8) and Biorthogonal (bior3.7). The
Gray-Level Co-occurrence Matrix is used for extracting 9 features at each sub-band. 27 features are
extracted at three sub-bands of Discrete Wavelet Transform. The features are extracted at three levels
of decomposition and after that the classification algorithm named as Naive Bayes, Multilayer
Perceptron, Fuzzy-NN and Genetic Programming are applied to extracted features. The feature selection
algorithms are applied named as Wavelet and Principle Component Analysis for selecting
the features and then classification accuracy is determined and compared between these.

Results:
Mammographic Image Analysis Society, database including 322 mammogram images from
161 patients is used. The classification algorithm without feature selection named as Fuzzy-NN
gives better results at the third level of decomposition having classification accuracy for db8 wavelet
family up to 99.68% and for bior3.7 wavelet family up to 99.98%. Wavelet with Multilayer Perceptron
using feature selection algorithm gives the classification accuracy for db8 wavelet family up
to 96.27% and for bior3.7 up to 93.47%.

Conclusion:
Fuzzy-NN algorithm gives highest accuracy of 99.98% for bior3.7 wavelet family. It
indicates that with feature selection and without feature selection, the wavelet families differ as db8
is better consideration for with feature selection and bior3.7 wavelet family for without feature selection.
A Virtual Reality Video to Improve Information Provision and Reduce Anxiety Before Cesarean Delivery: Randomized Controlled Trial
Authors: Noben Lore , Goossens Simone Maria Theresia Anna , Truijens Sophie Eva Marieke , van Berckel Marijn Marthe Georgine , Perquin Christel Wilhelmina , Slooter Gerrit Dirk , van Rooijen Stefanus Johannes 
Published: December 2019

Background
Anxiety levels before cesarean delivery (CD) can lead to a negative birth experience, which may influence several aspects of the woman’s life in the long term. Improving preoperative information may lower preoperative anxiety and lead to a more positive birth experience.

Objective
This study aimed to determine whether a virtual reality (VR) video in addition to standard preoperative information decreases anxiety levels before a planned CD.

Methods
Women scheduled to undergo term elective CD were recruited from the outpatient clinic. They were randomized and stratified based on history of emergency CD (yes or no). All participants received standard preoperative information (folder leaflets and counseling by the obstetrician); the VR group additionally watched the VR video showing all aspects of CD such as the ward admission, operating theater, spinal analgesia, and moment of birth. The primary outcome measure was a change in score on the Visual Analogue Scale for Anxiety (ΔVAS-A) measured at admission for CD, compared with the baseline VAS-A score.

Results
A total of 97 women were included for analysis. The baseline characteristics were similar in both groups, except for a significantly higher level of education in the control group. There was no significant decrease in the VAS-A score of the women in the VR group (n=49) compared with those in the control group (n=48; ΔVAS-A=1.0; P=.08; 95% CI −0.1 to 2.0). Subgroup analysis for the group of women with a history of emergency CD showed a trend toward decreased preoperative anxiety, despite the small sample size of this subgroup (n=17; P=.06). Of the 26 participants who provided completed questionnaires, 22 (85%) in the VR group reported feeling more prepared after seeing the VR video; of the 24 participants’ partners who completed the questionnaires, 19 (79%) agreed with the participants. No discomfort or motion sickness was reported.

Conclusions
A VR video may help patients and their partners feel better prepared when planning a CD. This study showed that VR does not lead to a decrease in preoperative anxiety. However, subgroups such as women with a history of emergency CD may benefit from VR videos.

Trial Registration
International Standard Randomised Controlled Trial Number (ISRCTN) 74794447; http://www.isrctn.com/ISRCTN74794447 (retrospectively registered)
Kajian Kliniko-patologik dan Antimikroba Ekstrak Biji Alpukat (Persea Americana Mill)
Authors: Santosa Christin Marganingsih , Rosyadi Imron , Arifianto Dinar , Siti Salasia Isrina Oktavia 
Published: December 2019

The phytochemical components of avocado seeds (Persea americana Mill) consist of alkaloids, flavonoids, tannins and saponins, so that they have the potential as antibacterials. The aim of this study was to determine the ability of Persea americana Mill extract to inhibit the growth of Staphylococcus aureus through inhibition zone observation and the ability to accelerate wound healing infected by S. aureus through observation of wound closure and cytopathology. Persea americana Mill were extracted using maceration method with 70% ethanol. The activities of this extract were tested by diffusion disc agar method. Biomedical tests were carried out on anaestetic Wistar rats whose were S. aureus infected wounds and treated with Persea Americana Mill extract. Based on the results of the antimicrobial test, avocado seed extract has a inhibitory effect on the growth of S. aureus at a concentration of 6.25% and best at a concentration of 100% compared to the control. Tests in experimental rats showed the effect of wound healing on the 2rd day after giving the extract Persea americana Mill ointment, faster than the control, which was need 4 days of wound closure. Cytopathology results showed that leukocyte activity was more prominent in rats treated with avocado seed extract compared to control rats. Avocado seeds as byproducts have the potential to be new herbal medicines that can be used as antimicrobials of S. aureus which have been confirmed to be resistant to various antibiotics.
Keanekaragaman Kapang Patogen dan Non Patogen pada Imago, Kokon, dan Larva Instar Keenam Ulat Sutera Liar Attacus atlas (Lepidoptera: Saturniidae)
Authors: Indrawati Agustin , Ekastuti Damiana Rita , Pangestika Erdina , Alwina Reinilda 
Published: December 2019

Attacus atlas is one of several mould species in Indonesia known as kupu-kupu gajah. Information about variety of mould is rarely known. The purpose of this research was to obtain data about variety of pathogenic or non pathogenic mould at imago,cocoon, and sixth larvae phase of wild silkworm A. atlas. Mould was isolated from cocoon, integument, alimentary duct and reproduction duct of imago, trachea, midgut and hindgut, also haemolymph of larvae. Isolated mould was cultured on potato dextrose agar. Isolated mould from cocoon and imago was identified by macroscopic and microscopic observation. The results showed that there were two kind of moulds from cocoon which were Fusarium oxysporum and Aspergillus flavus. There were four kind of moulds from imago A. atlas which were Aspergillus flavus, Aspergillus versicolor, Aspergillus fumigatus, Fusarium dimerum, and Aspergillus sp.There were three kind of moulds from sixth larvae which were Aspergillus fumigatus, Aspergillus flavus, and Fusarium dimerum. The mould which has opportunistic pathogenic for Attacus atlas were Fusarium oxysporum, Aspergillus flavus, Aspergillus fumigatus and Fusarium dimerum.
Pengaruh Perlakuan Amoniasi Fermentasi (AMOFER) Terhadap Kualitas Fisik Janggel Jagung
Authors: Candrasari Dewi Puspita , Fitria Restuti , Hindratiningrum Novita 
Published: December 2019

Permasalahan ketersediaan pakan ternak ruminansia dapat diatasi dengan memanfaatkan limbah hasil pertanian, perkebunan dan agroindustri. Salah satu contoh limbah pertanian yang memiliki potensi besar untuk diolah menjadi pakan adalah janggel jagung. Janggel jagung dapat dimanfaatkan sebagai sumber serat karena kandungan serat kasarnya yang tinggi. Akan tetapi terdapat beberapa kelemahan janggel jagung jika dijadikan bahan pakan yaitu kandungan protein serta kecernaan janggel jagung yang rendah sehingga perlu upaya untuk meningkatkan kualitas janggel jagung sebagai bahan pakan dengan perlakuan amoniasi dan fermentasi. Tujuan penelitian ini untuk mengevaluasi level penambahan M21 dekomposer dan lama pemeraman yang optimal terhadap kualitas fisik amoniasi fermentasi janggel jagung. Penelitian menggunakan Rancangan Acak Lengkap (RAL) pola faktorial. Perlakuan yang diberikan adalah penambahan M21 dekomposer atau aras starter komersial (0; 0,02; 0,04; 0,06 % dari total larutan formula) dan lama pemeraman (0, 14, 28 hari). Variabel yang diamati meliputi warna, bau/aroma, tekstur dan ada atau tidaknya pertumbuhan jamur. Data yang diperoleh diolah secara deskriptif. Hasil penelitian menunjukkan bahwa perlakuan amoniasi fermentasi menyebabkan perubahan warna menjadi coklat, bau/aroma menjadi asam dan tercium bau amonia, tekstur pada janggel jagung menjadi lebih lunak dan tidak ada pertumbuhan jamur. Perubahan kualitas fisik tersebut dapat disimpulkan bahwa perlakuan Amoniasi fermentasi mampu meningkatkan kualitas fisik janggel jagung.
A CONSTRUÇÃO DA SORORIDADE NOS DISCURSOS DA REVISTA AZMINA
Authors: M. M. MACHADO Liliane , Da Silva SCHONS Aline , Silva de MELO DOURADO Laila Carolline 
Published: December 2019

O artigo promove a análise de discurso da revista on-line AzMina, concentrada na sororidade. Observamos como os discursos jornalísticos, assumidamente construídos a partir de uma perspectiva feminista, ressignificam um tema polêmico para as feministas quanto a sororidade. Como aporte teórico elegemos as teorias feministas e de gênero, da comunicação e do jornalismo. Como metodologia optamos pela Análise de Discurso de vertente francesa. O corpus selecionado inclui dez textos que evidenciaram três formações discursivas: Sororidade como estratégia de combate à estrutura social violenta; Sororidade como estratégia de desnaturalização de estereótipos: inveja, rivalidade e falsidade entre mulheres; e Sororidade como estratégia feminista prática. As publicações rompem com o senso comum que sustenta a ideia da desunião das mulheres, e o fazem desconstruindo de forma crítica as estruturas sociais que sustentam a lógica patriarcal.
Palavras-chave
jornalismo; sororidade; AzMina; análise de discurso; estudos feministas e de gênero.
RESENHA DE ENHANCING SCHOOL SCIENCE WITH INDIGENOUS KNOWLEDGE: WHAT WE KNOW FROM TEACHERS AND RESEARCH
Authors: Crepalde Rodrigo dos Santos 
Published: December 2019

Trata-se de uma resenha da obra Enhancing school science with indigenous knowledge: what we know from teachers and research, de Aikenhead e outros autores. A obra é uma contribuição valiosa a partir de uma experiência concreta em uma rede de ensino canadense e que se torna leitura obrigatória para aqueles interessados nas contribuições da interculturalidade, especialmente ao modo como é tratado o conhecimento tradicional, para o ensino e aprendizagem de ciências. O texto é organizado por meio de narrativas de professores da rede de ensino sobre suas experiências no processo de implementação do novo currículo. Essas narrativas oferecem o contexto, ou melhor, nas palavras dos autores, as histórias ajudam a aproximar o texto da vida, isto é, das práticas pedagógicas, das vivências e dos desafios enfrentados pelos docentes em direção da construção de uma proposta de ensino de ciências responsivo culturalmente (CReST – Culturally Responsive Science Teacher). A grande síntese que essa obra pode nos oferecer, coerente com a perspectiva intercultural, é que a ciência escolar, estendendo também à formação de professores, à didática e ao próprio currículo de ciências, tem como expectativa que os estudantes indígenas aprendam as explicações científicas, ao mesmo tempo que possam ter reconhecidas e fortalecidas suas identidades. Além disso, para os estudantes não-indígenas, a ciência escolar espera que eles também aprendam as explicações científicas, ao mesmo tempo que possam ampliar seus repertórios e visões de mundo ao compreender as perspectivas indígenas.
Pengaruh Kebiasaan Belajar Terhadap Prestasi Belajar Siswa
Authors: Wijaya Shendy Andrie , Novi W Roro Aditya , Saputri Septyalina Dian 
Published: December 2019

Tujuan penelitian adalah mengetahui pengaruh secara simultan delay avoidan, work method dan cara belajar terhadap prestasi belajar,. Metode penelitian yang digunakan adalah confirmatory research. Dalam penentuan sampel penelitian ini menggunakan metode Proportionate Stratified Rondom Sampling. Untuk memperoleh data penelitian melalui penyebaran angket kepada siswa-siswi kelas XI IPS 1, 2 dan 3 SMA Negeri 5 Jember. Data yang terkumpul akan di analisis dengan regresi linier berganda. Berdasarkan hasil penelitian menunjukkan hasil uji hipotesis secara simultan (uji f) diperoleh Fhitung= 93,006 > Ftabel = 2,769, dan hasil sig 0,000, sehingga H1 yang berbunyi “Delay Avoidan, Work Method, Cara belajar berpengaruh signifikan secara simultan terhadap prestasi belajar” diterima.Kata Kunci : Delay avoidan, Metode kerja, Cara belajar dan Prestasi belajar
Pengaruh Motivasi Terhadap Mahasiswa Untuk Berwirausaha
Authors: Bunga Achita Arum 
Published: December 2019

Tujuan penelitian ini adalah untuk mengetahui faktor yang mempengaruhi motivasi mahasiswa Jurusan Pendidikan Ekonomi untuk berwirausaha dan faktor yang dominan mempengaruhi motivasi mahasiswa Jurusan Pendidikan Ekonomi untuk berwirausaha. Jenis penelitian ini adalah penelitian kuantitatif dengan menggunakan rancangan penelitian faktorial. Hasil penelitian menunjukkan bahwa faktor yang mempengaruhi motivasi mahasiswa untuk berwirausaha adalah faktor laba, faktor kebebasan, faktor impian personal dan faktor kemandirian.