bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bioenergy and bioproducts from cashew apple bagasse: a scientometric overview and strategies for sustainable utilization
Authors: Barroso Tiago Linhares Cruz Tabosa , Ferreira Vanessa Cosme , Castro Luiz Eduardo Nochi , da Rosa Rafael Gabriel , de Souza Luiz Gustavo Antonio , Goldbeck Rosana , Forster‐Carneiro Tânia 
Published: December 2024

AbstractThe potential of cashew apple bagasse in advancing a circular bioeconomy is being recognized increasingly. Traditionally viewed as a mere byproduct, this agroindustrial residue is acknowledged for its value in producing biofuels and bioproducts through innovative processes. This review highlights the growing research on cashew apple bagasse, emphasizing its nutritional potential and versatility as a biomass platform for generating products. Advances in pretreatment and fermentation strategies have enhanced bioprocess efficiency and aligned these processes with sustainability goals by utilizing residual materials and reducing environmental impacts. Cashew apple bagasse has also demonstrated considerable promise for enzymatic applications, including enzyme immobilization and biopolymer production, such as polylactic acid. These applications offer eco‐friendly alternatives to conventional petroleum‐based products. Emerging trends in bioenergy research underscore the importance of overcoming technical challenges related to biomass pretreatment, carbon capture, and sustainable production technologies. Innovations in digital financing, artificial intelligence, and hydrogen production are pivotal for the commercial viability of biorefineries. Overall, the promising findings from studies on cashew apple bagasse highlight its crucial role in renewable energy and bioproducts, reinforcing its potential to contribute significantly to a sustainable and circular economy.
Instandsetzung und Verstärkung von Bestandsbrücken mit UHFB‐Aufbeton in den Niederlanden
Authors: Buitelaar Peter , Oettel Vincent 
Published: December 2024

AbstractUltrahochfester Beton (UHFB) wird in den Niederlanden seit den 1980er‐Jahren zur Instandsetzung und Verstärkung von z. B. Industrieböden und ‐belägen eingesetzt. Bei diesem als Compact‐Reinforced‐Composite‐(CRC‐)Prinzip bezeichneten Verfahren wird eine dünne UHFB‐Schicht auf den jeweiligen Untergrund aufgebracht. Dies ermöglicht eine schnelle Sanierung und Wiederinbetriebnahme der Flächen. Da viele der zwischen 1960 und 1980 errichteten Brücken in den Niederlanden Defizite hinsichtlich Tragfähigkeit und Dauerhaftigkeit aufweisen, wurde der Einsatz von UHFB im Brückenbau nach dem CRC‐Prinzip bereits in den 1990er‐Jahren von Rijkswaterstaat (niederländisches Ministerium für Infrastruktur und Wasserwirtschaft) untersucht und eine hybridbewehrte UHFB‐Aufbetonschicht als Standardlösung für die Instandsetzung und Verstärkung von Stahlbeton‐ und Spannbetonbrücken entwickelt. Inzwischen wurden in den Niederlanden zahlreiche Brückeninstandsetzungen und ‐verstärkungen mit diesem Verfahren durchgeführt. In diesem Beitrag wird die hybridbewehrte UHFB‐Aufbetonschicht zunächst kurz vorgestellt und anschließend ausführlich über ihre Anwendung am Beispiel der Voorster Brücke berichtet.
Shades of Feeling: How Facial Color Variations Influence Emotional and Health Perception
Authors: Heydari Faeze , Khalili‐Ardali Majid , Yoonessi Ali 
Published: December 2024

ABSTRACTThis study investigated how color variations in facial expressions influence our perception of emotions and health. Participants viewed color‐manipulated (CIE LAB color space) face images depicting seven emotional states and indicated their perceptions of each image's emotion and health. Our results suggest that facial color influences the perception of threat‐related emotions such as anger and disgust, as well as health perception. Increasing facial redness intensified the perception of anger, while increasing yellowness and lightness heightened the perception of disgust. Lightness affected perceptions of happiness and sadness, with lighter happy faces appearing happier and lighter sad faces appearing sadder. Additionally, enhancing redness and yellowness on faces led participants to perceive them as healthier. Our findings add to the existing literature and provide important insights into the role of colors in perceiving different emotions and health. These insights may significantly impact social interaction and communication, especially in situations where facial expressions play a critical role.
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Authors: Mazarati Andrey 
Published: December 2024

AbstractThere has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI. The focus is on two aspects of post‐TBI GMBA dysfunction that are relevant to epilepsy. First are impairments in intestinal permeability with subsequent translocation of gut bacteria into the bloodstream. Specifically, endotoxemia following TBI may have a serendipitous protective effect against PTE through lipopolysaccharide conditioning, which may be leveraged for the development of therapeutic interventions. Second are changes in microbial composition (i.e., dysbiosis). Here, the GMBA‐PTE connection is explored from predictive biomarker perspective, whereby the risk of PTE can be stratified based on specific microbial profiles. Finally, microbiota transplantation is discussed both as a tool to examine the role of gut microbiota in PTE and as a prelude to novel approaches for PTE therapy and prevention.
Impact of Kombucha Fermentation on the Flavor and Physicochemical Properties of Tea (Camellia sinensis) Flower Infusions
Authors: Wang Leyu , Sun Panjie , Huang Mengxin , Han Ziyi , Yu Haonan , Wang Kaixi , Liu Junsheng , Wu Yuanyuan , He Puming , Tu Youying , Li Bo 
Published: December 2024

ABSTRACTTea (Camellia sinensis) flower is a nutritious and affordable raw material for beverages. However, the taste of infusions brewed directly from tea flowers with hot water is not very appealing. In the work, the effects of kombucha fermentation on the sensory quality and chemical profiles of tea flower infusions were investigated. During the 5‐day fermentation experiment, the samples fermented for 1 day exhibited the best overall flavor characteristics. The flavor of this sample was significantly improved, with a marked increase in sweet aromas and a noticeable enhancement of fruity, sweet, and sour tastes. PacBio sequencing revealed that four Komagataeibacter spp. (88.64%), Novacetimonas hansenii (7.09%), and Zygosaccharomyces bisporus (97.55%) were the dominant bacterial and fungal species in the used Kombucha. A total of 80 volatiles were detected in all samples, and relative odor activity value (ROAV) analysis showed that alpha‐ionone, linalool, beta‐ionone, decanal, and 1‐octen‐3‐ol were the major contributors to the aroma perception. The pH value and the contents of caffeine, total catechins, amino acids, and proteins decreased, while the contents of total soluble sugars and 21 compounds including sugar derivatives, organic acids, and cyclic adenosine monophosphate (c‐AMP) significantly increased. These results provided new insights into the development of tea flower‐based kombucha beverage.
Prognostic Effect of Patterns of Local Extension and Satellitosis in cT3 Squamous Cell Carcinoma of the Oral Tongue: A Prospective Observational Study
Authors: Montalto Nausica , Battocchio Simonetta , Contro Giacomo , Gaudioso Piergiorgio , Mularoni Francesca , Ruaro Alessandra , Ramacciotti Giulia , Cazzador Diego , Spinato Giacomo , Carobbio Andrea Luigi Camillo , Taboni Stefano , Zanoletti Elisabetta , Piazza Cesare , Nicolai Piero , Ferrari Marco 
Published: December 2024

ABSTRACTIntroductionThe anatomy of the tongue is three‐dimensionally complex and is thought to play a central role in the local growth of oral tongue squamous cell carcinoma (OTSCC). Understanding patterns of tumor extension could improve a multimodal therapeutic approach. Thus, the main aim of this study was to provide a histological and microanatomical analysis of surgical specimens after compartmental surgery for OTSCC.Materials and MethodsThe present prospective observational study included primary cT3 OTSCC (according to the eighth edition of the TNM classification) treated in an academic tertiary referral center with curative compartmental surgery, from July 2016 to July 2019. Analysis of histologic macrosections allowed assessment of standard pathologic parameters as well as a detailed analysis of the position of OTSCC cells from microanatomic and topographic standpoints.ResultsOf the 28 patients included, 71.4% were males, with a mean age of 64.9 years. Nine (32.1%) patients presented satellitosis, which was always located within the T‐N tract. OTSCCs displaying satellitosis had a significantly higher median pathologic depth of invasion (DOI). A radiologic and pathological DOI > 15 mm significantly predicted the presence of satellites. There was a significant relationship between the presence of satellites and both positive lymph nodes and distant metastases.ConclusionApproximately one‐third of cases of intermediate‐to‐advanced OTSCC are characterized by tumor satellites located in the T‐N tract. DOI exceeding 15 mm and the presence of clinically appreciable nodal metastases best predict the presence of satellitosis. Satellite‐bearing OTSCC behave more aggressively, with an increased risk of distant metastasis and reduced survival.
Investigating the Association Between Hashimoto's Thyroiditis and Papillary Thyroid Cancer
Authors: Báez Berríos Adriana I. , Monaghan Mathilda , Brandwein‐Weber Margaret , van Gerwen Maaike 
Published: December 2024

ABSTRACTBackgroundHashimoto's thyroiditis' (HT) impact on the aggressive lymph node (ALN) status of papillary thyroid carcinoma (PTC) remains understudied.MethodsUnivariate and multivariate analyses assessed PTC aggressiveness markers, comparing PTC + HT to PTC alone from a single center retrospectively. ALN categorization included > 5 positive, ≥ 1 > 3 cm, and/or ≥ 4 with extranodal extension lymph nodes.ResultsOf 533 patients with PTC, 19.1% concurrently had HT. Compared to PTC alone, PTC + HT patients were predominantly female (p < 0.001), younger (p = 0.034), non‐smokers (p = 0.035), and had more pN0 stage tumors (p < 0.001). PTC + HT was associated with lower odds of pN1 stage (ORadj, 0.50) and lymphatic invasion (ORadj, 0.53). No significant differences were observed in ALN status, pT stage, lymphatic and perineural invasion, gross ETE, margin, and focality.ConclusionALN status does not differ between PTC with or without HT.
Lymphomas of the Parotid Gland in Denmark: A Nationwide Cohort Study
Authors: Al‐Shahrestani Fahd , Al‐Khafaf Ahmed Ehsan , Asheer Zain , Jelicic Jelena , Chanchiri Iman , Blocher Catharina E. , Aalling Sørensen Anne Kathrine , Møller Pedersen Lars , Gjerdrum Lise Mette Rahbek , Heegaard Steffen , Homøe Preben 
Published: December 2024

ObjectiveWe examined the epidemiology of parotid gland lymphomas (PGL), the incidence, survival rates, clinical features, and association with primary Sjögren's syndrome (pSS).MethodsThis retrospective nationwide cohort study analyzed data from Danish patients diagnosed with PGL between 2000 and 2020. Data were collected from medical records, the National Pathology Register, and the Danish lymphoma database. Statistical analyses included Kaplan–Meier curves, log‐rank tests, and Cox proportional hazards models.ResultsA total of 433 patients were included. The incidence rate was 0.39 per 100,000 person‐years, with PGL constituting 1.9% of all non‐Hodgkins lymphoma in Denmark. The average annual incidence was 2.7% (incidence rate ratio = 1.027, p < 0.01). Follicular lymphoma (FL) was the most common subtype with 154 cases (35.6%), followed by large B‐cell lymphoma (LBCL) with 119 cases (27.5%), and extranodal marginal zone lymphoma (EMZL) with 84 cases (19.4%). The median overall survival (OS) for FL was 9.5 years (95% CI 6.9–10.2), with 5‐year and 10‐year OS rates of 70% and 44%, respectively. For LBCL, the median OS was 7.8 years (95% CI 5.0–8.8), with 5‐year and 10‐year OS rates of 59% and 33%. EMZL had a median OS of 12.8 years (95% CI 9.0–16.3), with 5‐year and 10‐year OS rate of 83% and 55%. EMZL was significantly associated with pSS, relative risk 21.97 (95% CI 2.81–171.53). Advanced age, B symptoms, and elevated LDH levels were significantly linked to poorer overall survival.ConclusionThis study offers new epidemiological, clinical, and prognostic insights, with a focus on their association with pSS.Level of Evidence3 Laryngoscope, 2024
Longitudinal in silico imaging study comparing digital mammography and digital breast tomosynthesis systems
Authors: Lago Miguel A. , Badano Aldo 
Published: December 2024

AbstractBackgroundIn silico clinical trials are becoming more sophisticated and allow for realistic assessment and comparisons of medical image system models. These fully computational models enable fast and affordable trial designs that can closely capture trends seen on real clinical trials.PurposeTo evaluate three breast imaging system models for digital mammography (DM) and digital breast tomosynthesis (DBT) in a fully‐in‐silico longitudinal study.MethodsWe developed in silico models for three different breast imaging systems by modeling relevant characteristics such as detector technology, pixel size, number of projections, and angular span. We use a computational image reader to detect masses at different growing stages to compute the relative system performance. Similarly, we compare calcification cluster detectability across systems. The Detectability area under the ROC curve (AUC) was calculated for each combination of breast density, device model, lesion size and type, and search area. We compared the absolute and relative AUC values for DM and DBT. The trial consisted of 45 000 simulated images corresponding to 750 virtual digital patient models.ResultsWe observed proportional AUC values with increasing mass size. On the other hand, higher breast densities showed lower AUC values. For masses, we found significant performance differences between device models. The highest average AUC difference between DBT and DM was 0.109, benefiting DBT. For calcifications, DM showed higher performance than DBT, especially in highly dense breasts. The highest AUC difference on a model was –0.055, benefiting DM.ConclusionsIn this fully‐in‐silico imaging trial, we compared three imaging systems with different detector technologies on the same cohort of virtual digital patient models. We found that breast device systems can lead to visibility differences in masses and calcifications. Our longitudinal, multi‐device in silico study was possible because of the versatility and flexibility of in silico methods. This study shows the advantages of this in silico methodology in lowering the resources needed for device development, optimization, and regulatory evaluation.
Mycology in the agriscience classroom: A curriculum based on wild foraged mushroom certification
Authors: Kratz Carley , McKim Aaron , Bonito Gregory 
Published: December 2024

AbstractThe overarching goal of this impact project is to make mycology accessible to more agriscience educators and students. Lesson plans were prepared to link core competencies and science standards to the Wild‐Foraged Mushroom certification. Incorporating mycology into the classroom has many benefits, including discussions on food safety and regulation, the role of ecology in agroecosystems, and taxonomic identification skills. Fungi also play many different roles in the ecosystem, including decomposers, mutualists, and parasites. Lesson plans in three topic areas were produced: mushroom identification and fungal ecology, mushroom growth and food safety, and mushrooms as a renewable resource. Examples of hands‐on learning and connections to the Wild‐Foraged Mushroom certification are provided. This certification is available in the state of Michigan; however, lessons could be adapted for use in other regions of the United States. Looking at taxonomy, ecology, food science, and economics through the lens of mycology is an engaging way to motivate students while potentially helping them earn a certification.
‘Attitude Problems’: Racializing Hierarchies of Affect in Post‐Brown U.S. Science Education
Authors: Kirchgasler Kathryn L. 
Published: December 2024

ABSTRACTAttending to the affect of minoritized students now appears crucial to promoting just and dignity‐affirming science education. Yet, elevating affect as an objective of science learning has a history that predates equity reforms. This study explores the politics of scientific uptakes of affect that have long served to mark hierarchical differences between students. As part of the special issue Centering Affect and Emotion Toward Justice and Dignity in Science Education, this paper investigates how U.S. science classrooms became sites of affective intervention, especially aimed at Black, Mexican American, Puerto Rican, and Indigenous students. As a history of the present, the study examines research journals and curricular reform materials between the 1954 Brown desegregation ruling and a 1989 equity report. The analysis suggests that shifts in post‐Brown U.S. science education made it possible to order students along affective hierarchies that: (1) established differential emotional regimes for those classified as ‘culturally deprived’ versus ‘gifted’; (2) equated human dignity with developing a depoliticized scientific self; and (3) evaded questions of racism and cultural imposition, while enforcing onto‐epistemic hierarchies. The study explores implications for current science education scholarship by considering how three extant concerns—deficit discourses, the dichotomization of science from political activism, and assimilationist models of scientist‐like affect—stem in part from the field's own responses to racial desegregation and civil rights demands. The purpose of historicizing affect in science education is to unsettle the racializing premises, normalizing constructs, and depoliticizing effects of social science techniques inherited from our not‐so‐distant past.
Qualified by Virtue of Experience? Professional Youth Work in Britain 1960–1989
Authors: Clements Charlotte 
Published: December 2024

AbstractThis chapter explores the role of experiential expertise in the professionalisation of youth work following the influential Albemarle Report in 1960. It argues that this form of knowledge was valued and fully integrated into the recruitment, training and practice of youth workers in South London and Liverpool after 1960. The model of youth work at this time joined together academic and theoretical underpinnings with reflective practice and the expertise of experience. The youth workers who came into practice at this time also brought their experience of post-war welfare cultures, broadly speaking, and within youth work itself, to their roles in the Youth Service. The chapter considers c how the local experiences that youth workers shared with young people, and the lived experience of having grown up in the same social contexts and localities, shaped youth work to include or indeed sometimes be centred on a variety of forms of activism. While youth work did professionalise between 1960 and 1989, this process was incomplete and youth work struggled to gain the same status as other educational and welfare professions.
Quaker Women in Humanitarian and Social Action: Faith, Learning and the Authority of Experience
Authors: Roberts Siân 
Published: December 2024

AbstractThis chapter focuses on a group of Quaker women in Birmingham who participated in social, educational and humanitarian action locally, nationally and transnationally in the first half of the twentieth century. Motivated by a faith-inspired witness for peace and social justice, they sought to enable women and children in Birmingham, and in international theatres of war, to “fare well” in a more peaceful and equitable society. The chapter adopts a prosopographical approach to argue that their authority to act was founded on claims to knowledge and expertise that were underpinned by personal experience. As Quakers, their experiential faith provided a significant context for their understanding of experience as a valid way of knowing the social world. Drawing on their published writings and unpublished archival materials, the chapter explores how they constructed and performed their experiential expertise through autobiographical narratives. The emphasis then shifts to consider the ways in which they shared and validated their expertise as a community of experience and drew on a genealogy of earlier Quaker female experience to evolve an experiential pedagogy of social action. The chapter concludes with reflections on how they negotiated the limitations of experiential knowledge that was constrained by privileged class positions.
Conclusions
Authors: Radovich Violeta S. 
Published: December 2024

AbstractThe sea is often observed from the perspective of its chemical or physical composition. There is a lack of a social and cultural approach to the sea, as proposed with the concept of “oceanity” (IMPAC3, 2013), which aims to highlight the relationship between human beings and the ocean. In this sense, the integrated management of the sea proposes a comprehensive vision as opposed to a sectorized one. The concept of “integration”, described in the preamble of the UNCLOS, states that the problems of the sea are interrelated and should be considered as a whole.
International Regulation on Marine Platforms
Authors: Radovich Violeta S. 
Published: December 2024

AbstractThis chapter further analyses international conventions’ bills on the subject that have not entered into force. It uses the concept of normative integration as a methodological approach, critically assessing the interaction between the law of the sea, maritime law, environmental law and human rights law in the field of study. Contributions from maritime law have been focused on safety measures and monetary compensation of damage as a response to maritime disasters through different international conventions. Environmental law has caused a paradigm shift with the introduction of the precaution principle in Rio Declaration. As regards Law of the Sea, ITLOS has concluded that the precaution principle is a hard law principle. Human Rights Internartional Law contributions will also be studied. Finally, the Offshore Protocol to the Barcelona Convention will be analysed.
The Role of Feedback Type and Task Performance on Concurrent Emotions and Interest During Game-Based Learning
Authors: Cloude Elizabeth B. , Kormann Eva , Steiner Marco , Lindstedt Antero , Kiili Kristian , Ninaus Manuel 
Published: December 2024

AbstractBuilding adaptive game-based learning (GBL) interventions (e.g., immediate feedback) has been a recent effort to maximize learning effectiveness. State-of-the-art algorithms often overlook the concurrent emotions and motivation of individuals and its impact on GBL interventions. This pilot study utilized a 3 (feedback type: results, elaborative, attribution) x 2 (graph type: misleading, non-misleading) within-subjects design with MediaWatch, a GBL environment built to improve critical graph literacy. At an Austrian university, 41 students’ concurrent emotions and motivation were measured using validated surveys immediately after different types of feedback on tasks during GBL. Results showed a significant improvement in graph literacy after GBL. Different types of feedback and task performance influenced concurrent emotions and interest, but individual differences accounted for the largest variability explained in emotions and interest. The findings suggest that within-subject variability is crucial for understanding concurrent emotions and motivation to feedback types and task performance during GBL.