bluuebunny/crossref_metadata_2025_split huggingface dataset:
Working Conditions and Mental Health Status Related With Occupational Injury of Korean Outdoor Workers
Authors: Lee Wanhyung , Lee Junhyeong , Kim Ui-Jin , Yoon Jin-Ha , Choi Won-Jun , Ham Seunghon , Chung Eun Kyo , Kang Seong-Kyu 
Published: May 2020

Objective:
This study investigated the working conditions and mental health status linked to occupational injury among Korean outdoor workers.

Methods:
Socioeconomic and occupational characteristics were collected using self-reported questionnaires from 26,468 paid workers selected using the 5th Korean Working Conditions Survey. The relationships among mental health issues, occupational injury, and working outdoors were estimated by logistic regression.

Results:
Outdoor workers were relatively older with lower educational levels and income, worked longer, and had greater exposure to occupational hazards, higher occupational injury rate, significantly higher risk of sleep disturbances, and higher occupational injury rates due to sleep disturbances than non-outdoor workers.

Conclusions:
There was a significant relationship among working outdoors, sleep quality, and mental health-related issues due to exposure to occupational hazards. Specific occupational health and safety strategies are needed to protect the mental health of outdoor workers.
Study of the Correlation Between Multiple Chemical Sensitivity and Personality Using the Quick Environmental Exposure Sensitivity Inventory Questionnaire and the Temperament and Character Inventory
Authors: Lu Xi , Hisada Aya , Anai Akane , Nakashita Chihiro , Masuda Shota , Fujiwara Yuki , Kunugita Naoki , Katoh Takahiko 
Published: May 2020

Objective:
We conducted an analysis using the Quick Environmental Exposure Sensitivity Inventory to examine the correlation between multiple chemical sensitivity (MCS) and personality traits by using temperament and character inventory, and environmental exposures.

Methods:
An anonymous questionnaire was distributed to 667 employees working at an IT manufacturing plant in Japan. Variables including chemically sensitive population (CSP), personality, and environmental chemical exposure were individually evaluated using U-test, chi-squared test, and correlation analyses. We also did covariance structure analysis to build a structural equation model.

Results:
There was little direct impact of temperament on the CSP, while there was a significant impact of character on the CSP. Women were more likely to exhibit symptoms of CSP.

Conclusion:
MCS is correlated with personality, impacted more by character acquired later in life than innate temperament. There were sex differences in the incidence of MCS.
Early High-Risk Opioid Prescribing Practices and Long-Term Disability Among Injured Workers in Washington State, 2002 to 2013
Authors: Haight John R. , Sears Jeanne M. , Fulton-Kehoe Deborah , Wickizer Thomas M. , Franklin Gary M. 
Published: May 2020

Objective:
To estimate associations between early high-risk opioid prescribing practices and long-term work-related disability.

Methods:
Washington State Fund injured workers with at least one opioid prescription filled within 6 weeks after injury (2002 to 2013) were included (N = 83,150). Associations between early high-risk opioid prescribing (longer duration, higher dosage, concurrent sedatives), and time lost from work, total permanent disability, and a surrogate measure for Social Security disability benefits were tested. Measures of early hospitalization, body part, and nature of injury were included to address confounding by indication concerns, along with sensitivity analyses controlling for injury severity.

Results:
In adjusted logistic models, early high-risk opioid prescribing was associated with roughly three times the odds of each outcome.

Conclusion:
Exposure to high-risk opioid prescribing within 90 days of injury was significantly and substantially associated with long-term temporary and permanent disability.
Association Between Presenteeism/Absenteeism and Well-being Among Korean Workers
Authors: Jeong Wonjeong , Kim Yun Kyung , Oh Sarah Soyeon , Yoon Jin-Ha , Park Eun-Cheol 
Published: May 2020

Objective:
Absenteeism and presenteeism refer to loss in productivity related to sick leave and illness, respectively, which affect physical and mental health. We examined the association between presenteeism/absenteeism and level of well-being among Korean workers.

Methods:
We analyzed data from 44,019 participants who completed the 2017 Korean Working Conditions Survey. The World Health Organization Well-Being Index (WHO-5) was used to screen the well-being level. We examined the association between presenteeism/absenteeism and level of well-being using multiple linear regression.

Results:
WHO-5 scores were lower among workers who experienced presenteeism or absenteeism than those who experienced neither (presenteeism: β = −1.011, P < 0.0001, absenteeism: β = −0.403, P < 0.0001).

Conclusion:
Presenteeism and absenteeism were associated with lower level of well-being. We suggest that their management is important for maintaining the health of Koreans.
The Impact of Challenge and Hindrance Demands on Burnout, Work Engagement, and Presenteeism. A Cross-Sectional Study Using the Job Demands–Resources Model
Authors: Vinod Nair Anjali , McGregor Alisha , Caputi Peter 
Published: May 2020

Objective:
The present study used the Job Demands–Resources (JD-R) model to understand how perceiving job demands as a hindrance or a challenge can influence an individual's exhaustion and motivation and its effect on presenteeism.

Method:
A sample of 171 working Australians was used to test the relationships between job demands and job resources with presenteeism via burnout and work engagement.

Findings:
The results suggested that challenge demands were positively related to burnout and work engagement, while hindrance demands were positively related to burnout and negatively related to work engagement. Most direct and indirect pathways predicted in earlier work incorporating the JD-R model to understand presenteeism were replicated.

Conclusion:
Future research on larger nation-wide samples is needed to further explore the differentiating effects of job demands on presenteeism via burnout and work engagement.
Associations Between the Breakroom Built Environment, Worker Health Habits, and Worker Health Outcomes: A Pilot Study Among Public Transit Rail Operators
Authors: Jones Nathan M. , McDonnell Meghan , Sparer-Fine Emily , Rosner Bernard , Dennerlein Jack T. , Kales Stefanos , Messerlian Carmen 
Published: May 2020

Objective:
To investigate the association between the breakroom built environment and worker health outcomes.

Methods:
We conducted this study in a mass transit organization (rail). We collected a user-reported breakroom quality score (worker survey), a worksite health promotion score (validated audit tool), and self-reported worker health outcomes (survey).

Results:
Among the 12 breakrooms audited and 127 rail operators surveyed, the average worksite health promotion score was 9.1 (out of 15) and the average user-reported breakroom quality was 3.1 (out of 7). After multivariable regression, breakrooms with higher worksite health promotion scores and user-reported breakroom quality were associated with lower odds of depression and fewer medical disability days.

Conclusions:
This cross-sectional study demonstrates an association between the quality of the breakroom built environment and worker health, specifically depression and medical disability days.
Longitudinal Assessment of Health Symptoms in Relation to Neurotoxicant Exposures in 1991 Gulf War Veterans
Authors: Yee Megan K. , Zundel Clara G. , Maule Alexis L. , Heeren Timothy , Proctor Susan P. , Sullivan Kimberly A. , Krengel Maxine H. 
Published: May 2020

Objective:
This analysis examined the relationship between Gulf War (GW) exposures and health symptoms reported in three time periods over 20 years in Ft. Devens Cohort veterans.

Methods:
Repeated logistic regression models examined the association of exposures and health symptoms over time. Models included baseline age, active duty status, post-traumatic stress disorder status, sex, and time since deployment as covariates.

Results:
Exposure to tent heaters was associated with increased odds of crying easily and muscle twitching. Exposure to pyridostigmine bromide (PB) pills was associated with increased odds of depression and fatigue. Exposure to the Khamisiyah sarin plume was associated with increased odds of trouble concentrating and crying easily.

Conclusion:
This longitudinal analysis demonstrated an association between neurotoxicant exposures and increased odds of cognitive/mood, fatigue, and neurological symptoms. In addition, most symptoms increased over time since deployment regardless of exposure.
Follow-Up of Occupational Health Issues and Measures Taken in Fukushima Daiichi Nuclear Power Plant Where Decommissioning Work Has Continued Over 6 Years Since 2014
Authors: Mori Koji , Tateishi Seiichiro , Kubo Tatsuhiko , Kobayashi Yuichi , Hiraoka Ko , Kawashita Futoshi , Hayashi Takeshi , Kobashi Masaki , Kiyomoto Yoshifumi , Fukai Kota , Tahara Hiroyuki , Okazaki Ryuji , Ogami Akira , Igari Kazuyuki , Suzuki Katsunori , Kikuchi Hiroshi , Yoshikawa Toru , Mori Takahiro , Ito Ryotaro , Sakai Kazuhiro 
Published: May 2020

Objectives:
To follow up arising occupational health (OH) issues, measures taken, and their performances in the Fukushima Daiichi Nuclear Power Plant since 2014, and thus share experiences and extend the contribution of OH to long-term decommissioning work and preparation for future disasters.

Methods:
Necessary information from official reports and through the OH-related activities involved was collected and analyzed.

Results:
The issues were categorized into establishment of the OH management system, three individual issues, and others. During the 6 years until end 2019, the OH management system has been strengthened and OH measures have been enriched gradually by visualizing the broader picture, even though some resistance and problems have been encountered.

Conclusions:
Improvement in the autonomy of contractors and their ability to respond to environmental changes is necessary.
Prevalence of Burnout in Occupational and Environmental Medicine Physicians in the United States
Authors: Green-McKenzie Judith , Somasundaram Parvathi , Lawler Timothy , O’Hara Edward , Shofer Frances S. 
Published: May 2020

Objective:
To determine prevalence and key drivers of burnout in Occupational and Environmental Medicine physicians in the United States.

Methods:
A nationwide survey of Occupational Medicine physicians was conducted using the Qualtrics® platform. Burnout, measured by the Maslach Burnout Inventory®, Social Support, and Job Satisfaction were assessed.

Results:
The response rate was 46%, the overall burnout prevalence 38%, and most respondents were men (69%). The mean age and mean years in practice were 56 years and 20 years respectively. Physicians working in government/military (48%) and private medical center group settings (46%) were significantly more likely to report burnout, with consultants (15%) reporting the lowest rate.

Conclusions:
Although the overall burnout prevalence is lower in Occupational Medicine physicians compared with most specialties, the rate varies significantly by practice setting (15% to 48%) affirming the impact of organizational factors.
Nephrotoxicity/renal failure after therapy with 90Yttrium- and 177Lutetium-radiolabeled somatostatin analogs in different types of neuroendocrine tumors: a systematic review
Authors: Stolniceanu Cati Raluca , Nistor Ionut , Bilha Stefana Catalina , Constantin Volovat , Simona Volovat , Matovic Milovan , Stefanescu Cipriana , Covic Adrian 
Published: May 2020

Background/objective
Data regarding the nephrotoxicity of the peptide receptor radionuclide therapy (PRRT) with 90Yttrium- and 177Lutetium-radiolabeled somatostatin analogs (RSA) are inconclusive. We aimed to evaluate the short- and long-term nephrotoxicity following PRRT usage in patients with all types of neuroendocrine tumors (NETs).

Methods
A systematic review of observational studies reporting data about nephrotoxicity after treatment with 90Yttrium and 177Lutetium RSA was performed. Data on serum creatinine, creatinine clearance, glomerular filtration rate (GFR) and need for renal replacement therapy were compiled. We included patients with progressive, inoperable symptomatic G1, G2 and G3 different types of NETs. After searching in three electronic databases PubMed, Scopus and the Cochrane Library, from 1 January 1978 to November 2018, data were extracted and summarized using a random-effects model.

Results
The final analysis included 34 studies, comprising 5386 participants, enrolling patients with G1, G2, G3 NETs and a follow-up from 12 up to 191 months. Compared with renal function before treatment, measured/estimated glomerular filtration rate (m/eGFR) values changed after PRRT, with a mean annual decrease following PRRT between 2 and 4 mL/min/1.73 m2 suggesting different grades of nephrotoxicity after PRRT. When compared, 90Y-RSA and the 90Y-RSA-177Lu-RSA combination are associated with a higher m/eGFR decline compared to 177Lu-RSA alone.

Conclusions
PRRT can be followed by potentially serious long-term nephrotoxicity, despite kidney protection. The use of the quantified renal function combined with a long follow-up period and personalized dosimetry-based PRRT can reduce nephrotoxicity, in order to use the whole PRRT potential in the management of NETs.
Evaluating the Dietary Intakes of Energy, Macronutrients, Sugar, Fiber, and Micronutrients in Children With Celiac Disease
Authors: Ting Alison , Katz Tamarah , Sutherland Rosie , Liu Victoria , Tong Chai Wei , Gao Yajuan , Lemberg Daniel A. , Krishnan Usha , Gupta Nitin , Coffey Michael J. , Ooi Chee Yee 
Published: May 2020

ABSTRACTObjectives:Children with celiac disease (CD) follow a lifelong gluten‐free diet. This restrictive diet may be associated with nutritional compromise. Our objectives were, therefore, to evaluate the dietary composition (energy, macronutrients and micronutrients, and fiber) in children with CD compared with healthy controls (HC) and relationship between dietary composition and socioeconomic status.Methods:This cross‐sectional, case‐control study recruited children with CD ages 2 to 18 years and HC matched for age, sex, and socioeconomic status. Clinical, sociodemographic, and dietary information were collected. A false discovery rate correction was applied to the P‐value for multiple comparisons (q‐value).Results:Sixty‐five CD children were matched with 65 HC (mean [SD] age: 10.2 [3.6] vs 10.1 [3.7] years, P = 0.96). Compared with HC, CD children had higher intakes of energy (2413.2 [489.9] vs 2190.8 (593.5) kcal/day, P = 0.02), total fat (818.1 ± 180.9 vs 714.3 ± 212.2 kcal/day, q = 0.018), and subtypes of fat (saturated, polyunsaturated, and monounsaturated). There were no differences in other macronutrients, sugar, micronutrients, or fiber between CD and HC, and no difference in dietary intake among CD between socioeconomic disadvantage versus advantage. Children with CD had lower weight z‐scores (−0.06 [1.05] vs 0.47 [0.96], P = 0.003) and body mass index (BMI) z‐scores (−0.02 [0.88] vs 0.41 [1.09], P = 0.02) than HC.Conclusions:Children with CD had higher calorie and fat intake compared with HC. Despite this, CD children had lower weight and BMI z‐scores compared with HC.
Pediatric Recurrent Intentional Foreign Body Ingestion
Authors: Low Kapalu Christina M. , Ibrahimi Nadia , Mentrikoski Janelle M. , Attard Thomas 
Published: May 2020

ABSTRACTAlthough foreign body ingestion (FBI) is a common pediatric referral concern, intentional or recurrent FBI (RFBI) in youth is poorly defined. In adults, several subgroups of patients with psychiatric comorbidities account for a large portion of FBIs. A similar classification system and corresponding management recommendations are yet to be outlined in pediatrics. We report 3 patients with RFBI: a 16‐year‐old, African American boy with 22 admissions and 27 endoscopic procedures for FBI removal; a 4‐year‐old, African American boy with autism spectrum disorder admitted twice after delayed presentation of ingestion of magnets; and a 15‐year‐old Caucasian girl with a complex mental health history who presented twice after intentional ingestion to self‐harm. We also present a literature review of pediatric RFBI. Patients with RFBI require a nuanced, multidisciplinary management approach to address acute concerns and reduce subsequent ingestion. A behavioral taxonomy and treatment considerations are presented.
Intestinal Inflammation Alters the Expression of Hepatic Bile Acid Receptors Causing Liver Impairment
Authors: Negroni Anna , Fiaschini Noemi , Palone Francesca , Vitali Roberta , Colantoni Eleonora , Laudadio Ilaria , Oliva Salvatore , Aloi Marina , Cucchiara Salvatore , Stronati Laura 
Published: May 2020

ABSTRACTObjectives:The gut‐liver axis has been recently investigated in depth in relation to intestinal and hepatic diseases. Key actors are bile acid (BA) receptors, as farnesoid‐X‐receptor (FXR), pregnane‐X‐receptor (PXR), and G‐protein‐coupled‐receptor (GPCR; TGR5), that control a broad range of metabolic processes as well as inflammation and fibrosis. The present study aims to investigate the impact of intestinal inflammation on liver health with a focus on FXR, PXR, and TGR5 expression. The strategy to improve liver health by reducing gut inflammation is also considered. Modulation of BA receptors in the inflamed colonic tissues of inflammatory bowel disease (IBD) pediatric patients is analyzed.Methods:A dextran sodium sulphate (DSS) colitis animal model was built. Co‐cultures with Caco2 and HepG2 cell lines were set up. Modulation of BA receptors in biopsies of IBD pediatric patients was assessed by real‐time PCR and immunohistochemistry.Results:Histology showed inflammatory cell infiltration in the liver of DSS mice, where FXR and PXR were significantly decreased and oxidative stress was increased. Exposure of Caco2 to inflammatory stimuli resulted in the reduction of BA receptor expression in HepG2. Caco2 treatment with dipotassium glycyrrhizate (DPG) reduced these effects on liver cells. Inflamed colon of patients showed altered FXR, PXR, and TGR5 expression.Conclusions:This study strongly suggests that gut inflammation affects hepatic cells by altering BA receptor levels as well as increasing the production of pro‐inflammatory cytokines and oxidative stress. Hence, reducing gut inflammation is needed not only to improve the intestinal disease but also to protect the liver.
NASPGHAN Nutrition University (N2U)
Authors: Larson‐Nath Catherine , Goday Praveen S. , Fiechtner Lauren , Mangalat Nisha , Schwartz Sally , Scheimann Ann , Sentongo Timothy , Turner Justine M. ,   NASPGHAN Committee on Nutrition
Published: May 2020

ABSTRACTThe North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) developed NASPGHAN Nutrition University (N2U) in 2012 to improve nutrition education for pediatric gastroenterology providers. A total of 543 providers (physicians, registered dietitians, and advanced practice nurses) have applied to N2U and 285 have attended this 2‐day course. We used survey methodology to compare attendees to applicants who did not attend. Course attendees reported more confidence than nonattendees in the nutritional management of patients with short bowel syndrome, feeding disorders, and gastrointestinal allergies, even though they were seen at similar frequency in both groups. Eighty‐eight percent of attendees disseminated the information they learned at N2U through venues such as grand rounds or guideline/policy development. These results demonstrate the benefit of N2U in enhancing nutrition education for pediatric gastroenterology practitioners.
Sharing Roles and Control in Pediatric Low Risk Febrile Neutropenia: A Multicenter Focus Group Discussion Study Involving Patients, Parents, and Health Care Professionals
Authors: Morgan Jessica E. , Phillips Robert S. , Stewart Lesley A. , Atkin Karl 
Published: May 2020

Introduction:
Reducing treatment intensity for pediatric low risk febrile neutropenia may improve quality of life, and reduce hospital-acquired infections and costs. Key stakeholders’ attitudes toward early discharge regimens are unknown. This study explored perceptions of reduced therapy regimens in the United Kingdom.

Materials and Methods:
Three study sites were purposively selected for their approaches to risk stratification, treatment protocols, shared care networks, and geographical spread of patients. Patients aged 13 to 18 years, parents of children of all ages and health care professionals participated in focus group discussions. A constant comparison analysis was used.

Results:
Thirty-two participants spoke of their different roles in managing febrile neutropenia and how these would change if reduced therapy regimens were implemented, how mutual trust would need to be strengthened and responsibility redistributed. Having identified a need for discretion and a desire for individualized care, negotiation within a spectrum of control allows achievement of the potential for realized discretion. Nonattendance exemplifies when control is different and families use their assessments of risk and sense of mutual trust, along with previous experiences, to make decisions.

Conclusions:
The significance of shared decision making in improving patient experience through sharing risks, developing mutual trust, and negotiating control to achieve individualized treatment cannot be underestimated.
Fusion 68Ga–Prostate-Specific Membrane Antigen PET/MRI on Postoperative Surveillance of Juvenile Nasal Angiofibroma
Authors: Sakthivel Pirabu , Thakar Alok , Arunraj Sreedharan Thankarajan , Bhalla Ashu Seith , Kumar Rakesh 
Published: May 2020

Abstract
Prostate-specific membrane antigen (PSMA) is expressed universally in juvenile nasopharyngeal angiofibroma (JNA). As contrast enhancement of postoperative scar is common with contrast-enhanced MRI (CEMRI), diagnosis of residual/recurrent JNA remains perplexing. Prostate-specific membrane antigen PET targets only the neovasculature and may aid in resolving this dilemma. Positive contrast enhancement on CEMRI was noted in a patient after 30 years of initial surgery, simulating recurrence. However, there was no abnormal uptake in PSMA scan, which was confirmed by biopsy as postoperative fibrosis. 68Ga-PSMA PET/MRI fusion may be an easy and novel technique to aid in differentiating residual/recurrent disease from surgical site reparative tissue.
Low ADC in CNS Lymphoma
Authors: Pyatigorskaya Nadya , Galanaud Damien , Dormont Didier , Soussain Carole , Kas Aurelie 
Published: May 2020

Abstract
Patients with primary central nervous system lymphomas (PCNSLs) present with nonspecific clinical symptoms, which makes correct imaging evaluation essential for diagnostic and therapeutic management. In this work, we examined an 81-year-old man with recently discovered PCNSL using 18F-FDG PET/MRI, and we were able to differentiate between 2 lesions—PCNSL lymphoma extension and a recent ischemia. Our work shows that ischemia should be considered as a differential diagnosis for lymphoma progression. Although 18F-FDG PET or MRI alone cannot always give unambiguous solution, PET/MRI can greatly improve the diagnosis accuracy and help decide on the appropriate patient management.