bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exercise and Acceptance and Commitment Therapy for Chronic Pain: A Case Series with One‐Year Follow‐Up
Authors: Casey Máire‐Bríd , Cotter Niamh , Kelly Caoimhe , Mc Elchar Lisa , Dunne Cian , Neary Rachel , Lowry Damien , Hearty Conor , Doody Catherine 
Published: January 2020

AbstractIntroductionThere is growing evidence to support Acceptance and Commitment Therapy (ACT) in the management of chronic pain. However, there is a need for further research evaluating ACT combined with physical exercise, and few studies have assessed the long‐term impact of this type of intervention. This case series reports on the acceptability and impact of an ACT‐based multidisciplinary pain management programme on a range of health outcomes in both the short and long‐term.MethodsSeventy‐three participants completed an 8‐week group‐based, pain management programme. The programme combined weekly sessions of ACT with education and exercise classes. Self‐report outcome measures were completed at baseline, post‐intervention and at one‐year follow‐up. The measures assessed pain intensity and interference, psychological distress, self‐efficacy, pain acceptance, values‐based action, pain catastrophizing, fear avoidance and healthcare utilization. Pedometers were worn to objectively measure physical activity. Data were analyzed using linear mixed modelling. Ethical approval for this study was granted by the Mater Misericordiae University Hospital (MMUH) Institutional Review Board (Reference 1/378/1541).ResultsEighty‐six percent of respondents reported being satisfied with the intervention. Improvements were observed in most of the self‐report outcomes post‐intervention and many changes were maintained at one‐year. There was also a significant increase in average daily step‐count.ConclusionA pain management programme combining ACT with exercise appears to be an acceptable treatment option for people with chronic pain. While improvements were observed in both the short and long‐term, further fully powered RCTs with long‐term follow‐up are required to test the effectiveness of this type of intervention.
The Effect of Extract from Dill Anethum Graveolens on the Growth Performance, Body Composition, Immune System, and Antioxidant System of Rainbow Trout
Authors: Zeilab Sendijani Reza , Abedian Kenari Abdolmohamad , Smiley Amir Hossien , Esmaeili Noah 
Published: January 2020

Abstract
In recent years, supplementing herbal medicines to fish diets in the aquaculture industry as a growth stimulant and immunostimulant is a common practice. In the present study, we investigated the effect of hydroalcoholic extract of dill on the growth performance and body composition of Rainbow Trout Oncorhynchus mykiss and its inhibitory effect against Aeromonas hydrophila in vitro. We also evaluated the immune responses and antioxidant system in fish that were fed dill diets over a period of 56 d. For this purpose, 180 Rainbow Trout fingerlings (initial weight 13.30 ± 0.22 g; mean ± SD) were purchased and they were fed four experimental treatments, which included a control diet and diets that were supplemented with 1Dill (1 g/kg dill extract), 1.5Dill (1.5 g/kg dill extract), or 3Dill (3 g/kg dill extract). According to the results, the fish that were fed 1Dill (54.70 g) and 1.5Dill (53.19 g) diets had significantly higher weight gain, although the feed conversion ratio was not significantly different among groups. However, the fish that were fed the 1.5Dill (62.55%) diet had significantly higher protein contents in the body than those that were fed the 3Dill (60.09%) treatment; the fish that were fed the 3Dill (29.00%) diet had higher lipid content than those that were fed the other diets. Regarding immune and antioxidant systems, the Rainbow Trout that were fed the 1.5Dill diet had significantly higher values of lysozyme in their serum (53.33 U/mL), alternative complement pathway hemolytic activity (146.33 U/mL), superoxide dismutase (52.33 U/mg protein), and catalase activity (164.66 U/mg protein) than the others did. Dill extracts in different dosages had no inhibitory effect against A. hydrophila in vitro. In summary, it can be concluded that the 1.5Dill diet can be used as a natural stimulant of growth, immunity, and the antioxidant system in the aquaculture industry.
Eastern Oyster Crassostrea virginica Growth and Mortality in New Hampshire (USA) Using Off-Bottom Farm Gear
Authors: Grizzle Raymond , Ward Krystin , Burdick David , Payne Andrew , Berlinsky David 
Published: January 2020

Abstract
Eastern oyster farm production has increased dramatically in the northeastern United States in recent decades. Farming methods vary, but different configurations of off-bottom “rack-and-bag” gear are commonly used and there is little published research on how different methods affect oyster growth. Field experiments were conducted during 2016–2018 on two farm sites in New Hampshire to assess the effects on oyster growth and mortality of different gear deployment configurations: (1) bag height above the bottom; (2) different combinations of oyster seed size, bag mesh size, and stocking density; (3) rack-and-bag versus bottom tray; (4) oyster seed size and over-winter mortality; and (5) envelope- versus box-style bags. Bag stocking density consistently had the strongest effect, with oyster growth being up to 3 times faster in bags that were stocked at 0.5 L compared with 2.0 L of wet oysters. Additionally, stocking density had a stronger effect on the oysters that were in 6-mm mesh bags than on those that were in 4-mm mesh bags. Oysters that were in bags in the top level of the rack grew significantly faster in one experiment but not in another. There was no significant difference in oyster growth comparing rack-and-bag and bottom trays. The over-winter mortality of oysters that were raised in rack-and-bag gear averaged 17% in one experiment and 46% in another. Early growth was similar for oysters that were deployed in box- and envelope-style bags, but by the final measurement (at 2.4 months) oysters in the box-style bags were 18% larger. The major findings were interpreted in the context of the notion that food supply and the factors affecting it have strong effects on the growth of farmed oysters, so this dynamic should drive strategies to improve gear deployment methods. Additionally, the typical situation of widely varying differences in uncontrollable factors (e.g., currents or phytoplankton concentrations) among sites and their effects on gear deployment methods may best be addressed by site-specific empirical studies that are conducted by farmers.
Numerical study of the biaxial compressive strength of high strength concrete based on a yield design micromechanical approach
Authors: Naija Ahmed , Hassen Ghazi , Limam Oualid , Miled Karim 
Published: January 2020

SummaryThis paper presents a numerical study of high strength concrete microstructure effects on its uniaxial and biaxial compressive strengths. Concrete is first represented as a set of angular aggregates interacting within a cement paste matrix. Then, a yield design kinematic approach is conducted at the mesoscopic scale in order to determine the concrete compressive strength for a given loading path. The proposed model, having a low computational cost, is able to capture the main microstructure effects already observed in literature on concrete uniaxial compressive strength, in particular, the aggregates volume fraction and maximal size effects. Finally, the proposed model also predicts the biaxial failure envelope of high strength concrete and confirms some experimental trends observed in literature.
A concept analysis of confidence related to older people living with frailty
Authors: Underwood Frazer , Latour Jos M. , Kent Bridie 
Published: January 2020

AbstractAimTo describe and define a concept of confidence in the context of older people living with frailty, which is important to the worldwide healthy‐ageing agenda preventing decline in independence and well‐being.DesignConcept analysis informed by Walker and Avant's eight‐stage approach.MethodsElectronic databases (MEDLINE, CINAHL and PsychINFO) from 1994–2018 were searched. Published studies exploring confidence and excerpts of papers referencing older people, frailty and confidence informed the concept analysis. Extracted attributes informed model case and additional case development. Appraisal of antecedents, consequences and empirical referents informed the final concept's construction.ResultsThree overall defining attributes of confidence were identified in this concept analysis: physical, psychological and social. A central feature is personal control, influencing internal and external factors. These control factors can be enabling factors (positive factors) or dis‐enabling factors (negative factors), affecting the frail older persons overall physical health and mental well‐being.
The built environment and its impact on health outcomes and experiences of patients, significant others and staff—A protocol for a systematic review
Authors: Elf Marie , Anåker Anna , Marcheschi Elizabeth , Sigurjónsson Ásgeir , Ulrich Roger S. 
Published: January 2020

AbstractAimThis review will identify, evaluate and synthesize the literature related to evidence‐based design of healthcare environments and to identify impacts of the built environment on the outcomes and experiences of patients, significant others and staff.DesignA mixed‐method systematic review of literature 2010–2018.MethodsDatabase searches for evidence in peer‐reviewed journals will be conducted electronically using CINAHL, Medline, SCOPUS and Web of Science. Abstract, full‐text screening and data extraction will be completed independently by the reviewers. Quality assessment will follow Swedish Agency for Health Technology Assessment and Social Services Assessment.ResultsThis review will offer knowledge for informed decisions about the design of the healthcare environment. The review is comprehensive, includes a large volume of literature various research designs and will highlight the knowledge gap in evidence‐based design and provide a breadth of knowledge about the built environments and its impact on health and well‐being.
Imaging of groundwater contamination using 3D joint inversion of electrical resistivity tomography and radio magnetotelluric data: A case study from Northern India
Authors: Devi A. , Israil M. , Singh A. , Gupta Pravin K. , Yogeshwar P. , Tezkan B. 
Published: January 2020

ABSTRACTThe impact of untreated sewage irrigation and waste disposal practices on groundwater is investigated by 3D joint inversion of radio magnetotelluric and electrical resistivity tomography data. In this case study, electrical resistivity tomography and radio magnetotelluric field measurements were carried out on several profiles near a waste disposal site which was irrigated with untreated sewage water for agriculture purpose. In addition, radio magnetotelluric and electrical resistivity tomography measurements were carried out, far away from the waste site, to derive the uncontaminated geology. The data were analysed earlier using 2D inversion techniques. However, for the 2D inversion of the electrical resistivity tomography and radio magnetotelluric data, assumptions about the strike direction are required. As no clear strike direction is evident for the contamination, we considered the problem as 3D and interpreted the present data set using the 3D inversion algorithm ‘AP3DMT‐DC’. The inverted 3D resistivity model shows an unconfined aquifer of low resistivity which is overlain by an unsaturated slightly resistive near surface formation. With increasing distance from the waste sites, an increase in the resistivity of the shallow unconfined aquifer is observed. Furthest away from the waste site undisturbed geology is expected. We derived consistent and meaningful 3D resistivity models. The uncontaminated reference site indicates an increased resistivity for the aquifer layer. A synthetic 3D study was carried out to demonstrate and validate algorithm performance as well as convergence capabilities. The study demonstrates that the two methods, electrical resistivity tomography and radio magnetotelluric, complement each other. Besides, a better resolved inverted model is obtained through a 3D joint inversion, in comparison to individual 2D and 3D inversions.
Mobile Application Interventions and Weight Loss in Type 2 Diabetes: A Meta‐Analysis
Authors: Cai Xue , Qiu Shanhu , Luo Dan , Wang Limin , Lu Yanhu , Li Mingzi 
Published: January 2020

ObjectiveThis meta‐analysis aimed to assess the effect of mobile application (app) interventions on weight loss in patients with type 2 diabetes.MethodsElectronic databases were searched for randomized controlled trials examining the use of mobile app interventions with outcomes on weight loss evaluated by body weight or other measures such as BMI or waist circumference. A random‐effects model was applied to obtain weight mean differences and 95% CIs.ResultsFourteen studies enrolling 2,129 patients with type 2 diabetes were included. Mobile app interventions could significantly reduce body weight (weight mean difference, −0.84 kg; 95% CI: −1.51 to −0.17 kg) and lower waist circumference (−1.35 cm; 95% CI: −2.16 to −0.55 cm) but may not decrease BMI (−0.08 kg/m2; 95% CI: −0.41 to 0.25 kg/m2). The reductions appeared to be more pronounced in patients with obesity or among studies using mobile app interventions combined with other behavior components. However, weight loss was not moderated by the functionalities of the mobile apps (all Pinteraction > 0.05) or by the intervention duration (all P > 0.87).ConclusionsMobile app interventions lead to weight loss in patients with type 2 diabetes and are worth recommending for weight loss promotion.
Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
Authors: Holmbäck Ulf , Forslund Anders , Grudén Stefan , Alderborn Göran , Söderhäll Arvid , Hellström Per M. , Lennernäs Hans 
Published: January 2020

SummaryObjectiveThere is an unmet medical need for a safe and effective weight loss product with minimal systemic side‐effects. In this study, the effect of a novel modified‐release fixed‐dose combination of orlistat and acarbose (MR‐OA) was compared with conventional orlistat (CO) regarding tolerability, appetite and glucose metabolism.MethodsSixty‐seven men with obesity, aged 24 to 60 years with body mass indexes (BMIs) 33 to 40 kg m−2 or BMIs 30 to 32 kg m−2 and waist circumference above 102 cm were included. They were randomized to either three different doses of the test formulation MR‐OA (60 mg orlistat/20 mg acarbose, 90/30 and 120/40) or CO (Xenical, 120 mg orlistat) for a 2‐week study of daily treatment. The participants spent days 1 and 14 at the clinical research centre where they received standardized meals, had blood sampling and filled in questionnaires regarding tolerability and appetite after meals. In days 2 to 13, the participants were at home and continued to fill in the questionnaires daily.ResultsIn the MR‐OA groups, reports of liquid and oily stools as well as faecal incontinence were fewer, whereas reports of gastric distension and flatulence were higher, compared with the CO group. More participants reported decreased hunger in the 90/30 and 120/40 MR‐OA, and postprandial plasma glucose concentration was reduced in all MR‐OA groups compared with CO.ConclusionsThis study shows that by using a modified‐release dosage form, orlistat and acarbose can be combined without compromising tolerability. Furthermore, MR‐OA shows promising effects regarding reduction of appetite and reduces postprandial glucose. Tolerability is coupled to compliance and thereby efficacy of a treatment; therefore, this novel combination MR‐OA could be an effective approach for weight loss treatment. A follow‐up study in a more diverse population and for a longer duration with weight loss as primary outcome variable is planned.
Characterization of fungicide sensitivity profiles of Botrytis cinerea populations sampled in Lombardy (Northern Italy) and implications for resistance management
Authors: Toffolatti Silvia L , Russo Giuseppe , Bezza Davide , Bianco Piero A , Massi Federico , Marcianò Demetrio , Maddalena Giuliana 
Published: January 2020

AbstractBACKGROUNDResistance to fungicides is one of the aspects that must be considered when planning treatments to achieve an optimal control of grey mold, caused by Botrytis cinerea, in vineyards. In this study, extensive fungicide resistance monitoring was carried out in Northern Italy (Lombardy region) to evaluate several aspects of fungicide resistance (frequency of resistance, effect of field treatments, mechanism of resistance and fitness) on 720 B. cinerea strains isolated from 36 vineyards.RESULTSOf the characterized strains, 12% were resistant to a single fungicide class (3% to the succinate dehydrogenase inhibitor boscalid, 4% to the anilinopirimidine cyprodinil; 5% to the phenylpirrole fludioxonil; 0.1% to the ketoreductase inhibitor fenhexamid) and 0.8% to two fungicide classes contemporaneously. Resistance was associated with mutations reported in the literature for boscalid (H272Y/R) and fenhexamid (P238S or I232M). Two new mutations in sdhC (A187F) and in sdhD (I189L) could be related to boscalid resistance. Strains resistant to fludioxonil did not show any known mutations. No significant differences were found in the fitness of sensitive and resistant strains.CONCLUSIONOverall, field populations of B. cinerea showed a relatively low frequency of resistance, but the geographical distribution of resistance, genetic mechanisms of resistance and fitness of resistant strains suggest that management of resistance should be implemented, at local and regional levels. Particular attention should be given to the fungicide sprays planned before veraison, since they seem to be associated with a higher frequency of resistant strains in vineyards. © 2020 Society of Chemical Industry
A simplified environmental evaluation tool for food packaging to support decision‐making in packaging development
Authors: Molina‐Besch Katrin , Pålsson Henrik 
Published: January 2020

AbstractPackaging developers in the food industry must consider several, sometimes conflicting, environmental requirements on packaging along with an already complex combination of marketing, logistics and production requirements. Existing methods for the environmental evaluation of packaging either focus on a limited amount of environmental packaging criteria (such as recyclability or renewable content) or rely on life cycle assessment methodology requiring expert competence. To support the food industry in their efforts toward developing product and packaging combinations that reduce the total environmental impact in food supply chains, this article presents a simplified environmental evaluation tool for food packaging. The presented tool was developed through an iterative process in a collaborative research project with the food industry. It evaluates packaging systems based on packaging criteria sorted into four areas that represent the life‐cycle steps packaging material production, transport, household and end‐of‐life. A comparison of the tool results and screening LCA results for three packaging cases showed no major differences. From the practitioners' perspective, the main advantages of the suggested tool are that it does not require LCA‐competence, that the required input data is commonly available in packaging development projects and that its overall structure invites several functions of the company to participate. The theoretical benefits of the suggested tool are that it allows for a parallel assessment of eco‐efficiency and eco‐effectiveness criteria in a life cycle perspective and that it considers littering risk as well as the influence of packaging on food waste in households
Exact solutions and spectrum analysis of a noncentral potential in the presence of vector potential
Authors: Ghosh Piu , Nath Debraj 
Published: January 2020

AbstractWe studied exact solutions and spectrum analysis of the pseudoharmonic oscillator in the presence of θ‐dependent scalar potential and the sum of two vector potentials Dirac magnetic monopole and Aharonov‐Bohm field. The effect of the Dirac magnetic monopole (g), Aharonov‐Bohm field (ℱ), the dissociation energy of diatomic molecules (D
e), equilibrium intermolecular separation (r
e), and the reduced mass (μ) on the energy spectrum for some diatomic molecules (CO, NO, N2, CH, H2, and ScH) are analyzed. We compared our results with theoretical experiments of pseudoharmonic oscillator potential in a molecular system.
What drives the short‐term fluctuations of banks' exposure to interest rate risk?
Authors: Memmel Christoph 
Published: January 2020

AbstractWe investigate whether banks actively manage their exposure to interest rate risk in the short run. Using bank‐level data of German banks for the period 2011Q4–2017Q2, we find evidence that banks actively manage their interest rate risk exposure in their banking books. Specifically, they adjust their exposure to the earning opportunities presented by this risk, take account of their regulatory situation, and manage this exposure using interest swaps. We also find that the fixed‐interest period of housing loans has an impact on the banks' overall exposure to interest rate risk. This last finding, in combination with the empirical evidence that customer preferences predominantly determine the fixed‐interest period of these loans, is not in line with active interest rate risk management.
Recursive methods for estimating the radial basis function‐based state‐dependent autoregressive model
Authors: Zhou Yihong , Ding Feng , Ji Yan , Hayat Tasawar 
Published: January 2020

SummaryIdentifying a nonlinear radial basis function‐based state‐dependent autoregressive (RBF‐AR) time series model is the basis for solving the corresponding prediction and control problems. This paper studies some recursive parameter estimation algorithms for the RBF‐AR model. Considering the difficulty of the nonlinear optimal problem arising in estimating the RBF‐AR model, an overall forgetting gradient algorithm is deduced based on the negative gradient search. A numerical method with a forgetting factor is provided to solve the problem of determining the optimal convergence factor. In order to improve the parameter estimation accuracy, the multi‐innovation identification theory is applied to develop an overall multi‐innovation forgetting gradient (O‐MIFG) algorithm. The simulation results indicate that the estimation model based on the O‐MIFG algorithm can capture the dynamics of the RBF‐AR model very well.
A Microfluidic Ion Sensor Array
Authors: Wu Chunxiao , Selberg John , Nguyen Brian , Pansodtee Pattawong , Jia Manping , Dechiraju Harika , Teodorescu Mircea , Rolandi Marco 
Published: January 2020

AbstractA balanced concentration of ions is essential for biological processes to occur. For example, [H+] gradients power adenosine triphosphate synthesis, dynamic changes in [K+] and [Na+] create action potentials in neuronal communication, and [Cl−] contributes to maintaining appropriate cell membrane voltage. Sensing ionic concentration is thus important for monitoring and regulating many biological processes. This work demonstrates an ion‐selective microelectrode array that simultaneously and independently senses [K+], [Na+], and [Cl−] in electrolyte solutions. To obtain ion specificity, the required ion‐selective membranes are patterned using microfluidics. As a proof of concept, the change in ionic concentration is monitored during cell proliferation in a cell culture medium. This microelectrode array can easily be integrated in lab‐on‐a‐chip approaches to physiology and biological research and applications.