bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Tubular Solute Clearance with Symptom Burden in Incident Peritoneal Dialysis
Authors: Wang Ke , Nguyen Michelle , Chen Yan , Hoofnagle Andrew N. , Becker Jessica O. , Zelnick Leila R. , Kundzins John , Goodling Anne , Himmelfarb Jonathan , Kestenbaum Bryan 
Published: March 2020

Background and objectives
Residual kidney function is important to the health and wellbeing of patients with ESKD. We tested whether the kidney clearances of proximal tubular secretory solutes are associated with burden of uremic and heart failure symptoms among patients on peritoneal dialysis with residual kidney function.

Design, setting, participants, & measurements
We enrolled 29 patients on incident peritoneal dialysis with residual urine output >250 ml daily. We used targeted liquid chromatography-mass spectrometry to quantify plasma, 24-hour urine, and peritoneal dialysate concentrations of ten tubular secretory solutes. We calculated the kidney and peritoneal dialysis clearances of each secretory solute, creatinine, and urea, and we estimated a composite kidney and peritoneal secretion score. We assessed for uremic symptoms using the Dialysis Symptom Index and heart failure–related symptoms using the Kansas City Cardiomyopathy Questionnaire. We used linear regression to determine associations of composite secretory solute clearances and GFRurea+Cr with Dialysis Symptom Index symptom score and Kansas City Cardiomyopathy Questionnaire summary score.

Results
Mean residual kidney clearances of creatinine and urea were 8±5 and 9±6 ml/min per 1.73 m2, respectively, and mean GFRurea+Cr was 8±5 ml/min per 1.73 m2. The residual kidney clearances of most secretory solutes were considerably higher than creatinine and urea clearance, and also, they were higher than their respective peritoneal dialysis clearances. After adjustments for age and sex, each SD higher composite kidney secretion score was associated with an 11-point lower Dialysis Symptom Index score (95% confidence interval, −20 to −1; P=0.03) and a 12-point higher Kansas City Cardiomyopathy Questionnaire score (95% confidence interval, 0.5- to 23-point higher score; P=0.04). Composite peritoneal dialysis secretion score was not associated with either symptom assessment.

Conclusions
Residual kidney clearances of secretory solutes are higher than peritoneal dialysis clearances. Kidney clearances of secretory solutes are associated with patient-reported uremic and heart failure–related symptoms.
DAMPAK PENERAPAN ICT PADA PEMBELAJARAN IPS TERHADAP MINAT BELAJAR PESERTA DIDIK
Authors: Munirah Munirah , Tuli Nurain , Arif Muh 
Published: March 2020

AbstrakArtikel ini bertujuan untuk mengungkap tentang dampak penerapan ICT pada pembelajaran IPS terhadap minat belajar peserta didik di SDN 2 Tabongo Gorontalo dan hambatan dalam Penerapan ICT pada Pembelajaran IPS. Jenis penelitian ini adalah penelitian kualitatif. Subjek penelitian ini adalah peserta didik SDN SDN 2 Tabongo Kecamatan Tabongo Kabupaten Gorontalo. Teknik analisis data yang digunakan adalah teknik deskriptif. Teknik pengumpulan data yang digunakan adalah wawancara dan pengamatan. Hasil temuan menunjukkan bahwa penerapan ICT pada pembelajaran Ilmu Pengetahuan Sosial telah mampu meningkatkan minat belajar peserta didik. Tingkat capaian persentase partisipasi siswa khusus mata pelajaran ilmu pengetahuan sosial pada tahun berjalan berkisar antara 80% sampai dengan 90%. Hal ini menunjukkan bahwa penggunaan ICT sangat membantu peserta didik meningkatkan pemahaman terhadap materi yang diajarkan dan wawasannya terhadap materi yang diajarkan meningkat.AbstractThis article aimed to determine the impact of ICT implementation on learning IPS toward the students’ learning interest at SDN 2 Tabongo Gorontalo and to find the obstacles in implementing ICT on learning IPS. The research used was qualitative method with descriptive approach. The subjects were the students of SDN 2 Tabongo subdistrict Tabongo District Gorontalo. The findings showed that the implementation of ICT on IPS learning was able to increase the students’ learning interest. The achievement rate of the percentage of the students ' participation was 80% to 90%. This result indicted that the implementation of ICT was very helpful for the students to increase their understanding of the material being taught.
Proposição de uma metodologia a partir do Balanced Scorecard (BSC) para suporte à gestão estratégica de uma empresa de transporte de carga frigorífica
Authors: Vieira Junior , Nascimento Sabrina Do , Dalbosco Inocencia Boita , Pavan Daiane 
Published: March 2020

Esta pesquisa tem por objetivo propor uma metodologia com base no Balanced Scorecard, para suporte à gestão estratégica de uma empresa de transporte de carga frigorífica. Na metodologia optou-se por um estudo de caso qualitativo básico realizado em uma empresa de transporte de carga frigorífica com sede na cidade de Chapecó no estado de Santa Catarina. A estratégia de coleta de dados adotada foi à análise de dados secundários (documentos gerenciais e relatórios contábeis) e também fontes primárias como entrevista abertas com os gestores da organização. Os resultados revelam que a adoção por parte da empresa de metodologias como o BSC que possam subsidiar o processo decisório tende a auxiliá-la a alcançar seus objetivos estratégicos e ainda proporcionar suporte a avaliação de seu desempenho. Como limitação apresenta-se a impossibilidade de generalização do estudo, devid as particularidades da empresa estudada. Sugere-se para futuras pesquisas a realização de estudo longitudinal na empresa de transportes analisada, afim de monitor o desempenho da organização com auxílio da metodologia proposta no curto, médio e longo prazo.
Surowce zielarskie orzecha włoskiego
Authors: GRUSZECKI ROBERT , CHMIST AGATA , WALASEK MAGDALENA 
Published: March 2020

W publikacji przedstawiono surowce zielarskie uzyskiwane z orzecha włoskiego i ich zastosowanie lecznicze. W pracy oparto się na polskich opracowaniach z zakresu fitoterapii, publikacjach zajmujących się medycyną tradycyjną i publikacjach naukowych dotyczących zastosowań leczniczych tej rośliny. Podstawowymi surowcami leczniczymi uzyskiwanymi z roślin orzecha włoskiego są liść (Juglandis folium) i naowocnia (Juglandis fructus cortex), jednak roślina ta oferuje znacznie większą gamę surowców: pączki (Juglandis gemmae), korę (Juglandis cortex), kwiat (Juglandis flos), owoc (Juglandis fructus), owoc niedojrzały (Juglandis immature fructus) oraz korzeń (Juglandis radix). Surowce pozyskiwane z omawianego gatunku stosowane są w medycynie tradycyjnej w wielu krajach świata przy schorzeniach skóry, przewodu pokarmowego, dróg oddechowych, robaczycy, bólach serca, głowy, bólach reumatycznych, chorobach kobiecych, cukrzycy, skrofułach, hemoroidach, biegunkach, przy problemach z tarczycą, gorączce, anginie, wrzodach gardła, zapaleniu spojówek, skurczach nóg, suchotach, febrze, malarii, a nawet przy impotencji i problemach z erekcją. Przeprowadzone badania naukowe często potwierdzają zalecenia medycyny ludowej oraz wskazują na wiele innych obiecujących zastosowań medycznych surowców otrzymywanych z tej rośliny. Wszystko to pozwala sądzić, że w przyszłości preparaty na bazie orzecha włoskiego będą zyskiwały na znaczeniu i popularności.
Estado actual de la educación para la sustentabilidad en escuelas de negocios en México
Authors: Murrieta Martinez Natalia 
Published: March 2020

A partir de la entrada en vigor de la Agenda 2030 para el Desarrollo Sostenible de la Organización de las Naciones Unidas (ONU), México ha realizado esfuerzos en la consecución de los 17 objetivos propuestos. Las Instituciones de Educación Superior, específicamente las Escuelas de Negocios, tienen en sus manos la oportunidad y la responsabilidad de contribuir directamente al logro de los Objetivos de Desarrollo Sostenible, debido a la naturaleza de los conocimientos, habilidades y aptitudes relacionadas que se desarrollan en esta etapa de la educación superior. Así, este ensayo presenta el estado actual de la incorporación de la educación para la sostenibilidad en las escuelas de negocio en México, encontrando que aún no son suficientes los esfuerzos realizados.
Restricted-Variance Molecular Geometry Optimization Based on Gradient-Enhanced Kriging
Authors: Raggi Gerardo , Ritterhoff Christian L. , Fernández Galván Ignacio , Vacher Morgane , Lindh Roland 
Published: March 2020

Machine learning techniques, specifically Gradient-Enhanced Kriging (GEK), has been implemented for molecular geometry optimization.GEK has many advantages as compared to conventional -- step-restricted second-order truncated -- molecular optimization methods.In particular, the surrogate model associated with GEK can have multiple stationary points, will smoothly converge to theexact model as the size of the data set increases, and contains an explicit expression for the expected average error of the model functionat an arbitrary point in space.In this respect GEK can be of interest for methods used in molecular geometry optimizations.GEK is usually, however, associated with abundance of data, contrary to the situation desired forefficient geometry optimizations.In the paper we will demonstrate how the GEK procedure can be utilized in a fashion such that in the presence of few data points, thesurrogate surface will in a robust way guide the optimization to a minimum of a molecular structure.In this respect the GEK procedure will be used to mimic the behavior of a conventional second-order scheme, but retaining theflexibility of the superior machine learning approach -- GEK is an exact interpolator.Moreover, the expected variance will be used in the optimization to facilitate restricted-variance rational function optimizations (RV-RFO).A procedure which relates the eigenvalues of the Hessian-model-function Hessian with the individual characteristiclengths, used in the GEK, reduces the number of empirical parameters to two -- the value of the trend function and themaximum allowed variance. These parameters are determined using the extended Baker (e-Baker) test suite, at the Hartree-Fock level of approximation,and a single reaction of the Baker transition-state (Baker-TS) test suite as a training set. The so-created optimizationprocedure -- RV-RFO-GEK -- is tested using the e-Baker, the full Baker-TS, and the S22 test suites, at the density-functional-theory level for the two Baker test suitesand at the second order Møller-Plesset level of approximation for the S22 test suite, respectively.The tests show that the new method is generally on par with a state-of-the-art conventional method, while for difficult cases it exhibits a definite advantage.
PENGALAMAN ANAK USIA SEKOLAH DALAM MENGGUNAKAN SOSIAL MEDIA
Authors: Pratiwi Rini Intan , Lita Lita , Anggreny Yecy 
Published: March 2020

Globalisasi yang terjadi di era ini membuat proses berkomunikasi menjadi semakin cepat dan mudah. Kemudahan dalam proses komunikasi terjadi karena adanya jaringan internet, dan salah satu layanan komunikasi langsungnya adalah sosial media. Pengguna sosial media saat ini tidak hanya orang dewasa, tetapi juga anak usia sekolah. Penelitian ini bertujuan untuk menggali pengalaman anak usia sekolah dalam menggunakan sosial media. Penelitian ini adalah kualitatif dengan studi fenomenologi. Partisipan kunci pada penelitian ini berjumlah 8 orang siswa berusia 10-12 tahun dan menggunakan sosial media. Teknik sampling yang digunakan adalah metode snowball sampling. Metode pengumpulan data yang dilakukan adalah in-depth interview. Data dianalisa dengan menggunakan teknik Moustakas. Hasil penelitian ini didapatkan 4 tema, pertama adalah manfaat menggunakan sosial media (mendapatkan informasi, komunikasi, teman baru dan menyelesaikan tugas sekolah) kedua adalah kerugian (belajar terganggu dan mendapatkan jenis informasi negatif). Ketiga, yaitu pengembangan diri (mengembangkan hobi melalui menonton video). Terakhir, yaitu alasan menggunakan sosial media (menghilangkan rasa bosan, mendapat informasi terbaru dan berkomunikasi). Hasil penelitian ini dapat memberikan pengetahuan terhadap anak usia sekolah terkait hal yang di dapatkan dari sosial media, serta pengaruhnya terhadap pendidikan, perkembangan, dan hubungan sosial anak usia sekolah tersebut
Modern University in the Light of Lifelong Learning Challenges: The Issues of Philosophy of Education
Authors: Semeniuk Natalia 
Published: March 2020

The philosophical analysis of the content of the modern university's work leads to an understanding of commercialization and professional localization in the training of specialists. The ways of determining the essence of a modern university are grounded: elite, mass, niche, regional, pragmatic, ecological, and others. It is argued that the commercialization of education is conditioned by an increase in the level of technology impact on the dynamics of cultural development, globalization and informatization of society. Accordingly, traditional notions of academic freedom and the value of science and education are inferior to considerations of pragmatic feasibility and utilitarianism. The idea of ​​the perniciousness of such a trend in education that threatens the personality deformation and the possible risks of global catastrophes is upheld in the paper.
STATE-PRIVATE PARTNERSHIP − A MODEL FOR REFORMING UNIVERSITY CLINICS
Authors: Chopchik Vitaliy 
Published: March 2020

The aim of the work to substantiate the possibility of using public-private part- nership (PPP) as a tool for the innovative development of university clinics (UK).
Results the article reveals the problems of the current system of university clinics, shows the foreign experience of using public-private partnerships in healthcare. PPP mechanism is defined as the main tool for reforming university clinics. The main directions of the devel- opment of the UK, such as: regulatory, organizational, managerial, financial, informational, capable of providing a modern, autonomous, economically sustainable model of the UK, is also presented in the article.
Conclusions the article describes the current university clinics in Ukraine. Taking into account the experience of developed countries of the world, as well as the economic situation in Ukraine, a more effective form of organizing of UK on the principles of PPP as a tool for innovative development of university clinics is sustained.
TOMOGRAPHIC EXAMINATION OF CHANGES IN MUCOPERIOST OF THE MAXILLARY SINUS AFTER SINUS LIFTING
Authors: Shpachynskyi Oleksandr , Skibitskyi Vadym , Filippenkova Larisa , Vasilevskyi Kostiyntin , Didkovskyi Vyacheslav , Kopchak Andrii 
Published: March 2020

Restoration of the masticatory function in patients with edentulous posterior maxilla is often challenging due to the severe atrophy of the alveolar ridges and insufficient bone quantity for implant supported dentures. The purpose of this study was to analyze the change in mucoperiost after lateral sinus floor augmentation (LSFA) using cone beam com- puted tomography (CBCT).
LSFA procedures using different bovine bone materials with and withaut immediate implan- tation were performed at the Stomatological Medical Center of Bohomolets National Medical University in 87 patients, from 2016 to 2018. CBCT examination was performed before LSFA procedure in all patients, postoperative period: up to 1 month after surgery; and after 6 months, before implant placement or loading. Images were acquired using Planmeca ProMax 3D. Postop- erative CBCT performed in early postsurgical period demonstrated that the number of case with type A decreased significantly from 86,67 to 26,75%. The number of cases with type B radiological picture increased from 20,33% to 26,75 %. Mucoperiost type C was observed in 7,5 vs 41,73%. Type D and E were observed in 13.91 and 2.14% However, the clinical signs of the acute sinusitis or specific complaints were recorded only in 2 cases. In 3 cases radiological findings resembled to F type. According to the results of the present study the minor radiologic changes in mucoperiost morphology were observed preoperatively in 17.12% of patients who underwent LSFA proce- dures. The incidence of sinusitis or graft failure in long term follow up consisted 19.26 % while the frequency of asymptomatic radiological changes was significantly higher. It consisted 68.48 in early and 47.1 % in late (6 months) postoperative period. As the differential diagnosis for such changes based only on clinical and radiological data is difficult, the obtained results prove the im- portance of preoperative endoscopic examination, intraoperative and postoperative control in pa- tients with LSFA and the benefits of multidisciplinary approach of oral and ENT surgeons in asset of indications, ricks of the procedure, postoperative rehabilitation and complication management.
Yield formation of spring rape seeds with the seed treatment with micronutrients
Authors: Khairullin A. M. , Gayfullin R. R. , Sergeev V. S. , Chanyshev I. O. , Bagautdinov F. A. 
Published: March 2020

Relevance. Trace elements are of great importance in plant life. Due to their catalytic action, they allow plants to more effectively use the main elements of nutrition-solar energy, water and macronutrients — nitrogen (N), phosphorus (P) and potassium (K), which in turn has a positive effect on plant productivity and crop quality. Rape is very sensitive to the lack of boron, zinc. Trace elements are currently presented in various forms, and therefore the purpose of the research was to identify the effectiveness of boronand zinc-containing trace elements in the processing of seed material.Methods. Theobjectofstudyisspringrape(Brassicanapus) variety Yubileiny. Field experiments and studies were carried out in 2015–2017 in the Birsky district of the Republic of Bashkortostan. Tested options using micronutrient fertilizers: zinc sulfate, 21.5%; Ultramag chelate Zn, 15%; boric acid, 17.5%; Ultramag doron, 11%.Results. According to the results of studies, an increase in field germination by 6.5%, the yield of oilseeds by 37.1% and oilseeds by 1.7% when treated with Ultramag chelate Zn at a dose of 1 kg/ha was found.
The role of graining in ensuring food security
Authors: Gambarova R. M. 
Published: March 2020

Relevance. Grain is the key to strategic products to ensure food security. From this point of view, the creation of large grain farms is a matter for the country's selfsufficiency and it leading to a decrease in financial expense for import. Creation of such farms creates an abundance of productivity from the area and leads to obtaining increased reproductive seeds. The main policy of the government is to minimize dependency from import, create abundance of food and create favorable conditions for export potential.The purpose of the study: the development of grain production in order to ensure food security of the country and strengthen government support for this industry.Methods: comparative analysis, systems approach.Results. As shown in the research, if we pay attention to the activities of private entrepreneurship in the country, we can see result of the implementation of agrarian reforms after which various types of farms have been created in republic.The role of privateentrepreneurshipinthedevelopmentofproduction is great. Тhe article outlines the sowing area, production, productivity, import, export of grain and the level of selfsufficiency in this country from 2015 till 2017.
Penerapan Pendidikan Matematika Dasar Menggunakan Pendekatan Realistik untuk Anak Usia Dini di Kelurahan Kampung Lapai
Authors: Hasibuan Lilis Harianti , Putri Darvi Mailisa , Jannah Miftahul 
Published: March 2020

Penyuluhan yang berjudul Penerapan Pendidikan Matematika Dasar Menggunakan Pendekatan Realistik untuk Anak Usia Dini di Kelurahan Kampung Lapai mengajukan masalah bagaimana penerapan Pendidikan Matematika Dasar pada anak usia dini. Untuk mengatasi masalah di atas penulis mengajukan konsep agar anak usia dini bisa memahami pelajaran matematika dengan mudah dan menyenangkan. Pada anak usia dini perkembangan kemampuan matematis dimulai sejak kecil, dan berlanjut saat anak-anak berkembang secara mental, fisik, dan sosial, yang berpengaruh secara langsung terhadap perkembangan dan kemampuan mereka . Pendidikan matematika dapat diberikan kepada anak sejak usia 0-6 tahun. Anak pada usia 0-6 tahun perlu mendapaat perhatian khusus karena pada usis inilah kesiapan mental dan emosional anak mulai dibentuk. Pendidikan anak usia dini (PAUD) ikut serta dalam menjamin mutu pendidikan dan kebrhasilan akademis secara signifikan dipengaruhi oleh kualitas masukan pendidikan yaitu kesiapan mental dan emosional anak memasuki sekolah dasar. Metode dari penelitian ini adalah penelitian deskriptif.. Adapun sampel yang akan menjadi responden pada pengabdian ini adalah siswa PAUD Amanah dengan menggunakan analisis inferensial produc moment. Berdasarkan perhitungan diperoleh thitung lebih besar dari ttabel (5,231 > 1,694). Artinya terdapat hubungan positif yang tinggi atau kuat antara pendekatan realistik dan pemahaman matematika dasar pada anak usia dini
Indigenising Education: Scales, Interfaces and Acts of Citizenship in Sápmi
Authors: Sollid Hilde , Olsen Torjer 
Published: March 2020

As Indigenous people reclaim their position after centuries of oppression, the tensions between Indigenous needs and national demands surface. This is also the case of the Indigenous Sámi in Norway. After a long period of colonisation, recognition of the indigenous Sámi people and their language and culture is replacing the politics of erasure. In this process, the educational system is the institution where this new direction can reach the farthest. Rather than seeing Indigenous education as static endpoint in opposition towards mainstream education, we theorise that indigenising education is better understood as a process and as a continuum where citizens with different subject positions engage and interact in a cultural interface. The theorising is based on a case study from Gáivuotna-Kåfjord-Kaivuono on the Norwegian side of Sápmi.
The Impacts of Tax Examinations, Tax Sanctions and Tax Hostage (Gijzeling) on Taxpayers’ Formal Compliance
Authors: Puspitasari Dewi 
Published: March 2020

The purpose of this study is to determine whether there are impacts of tax audits (X1), tax sanctions (X2), and tax holdings (X3), on formal compliance of taxpayers (Y). The population in this study is the taxpayers registered with KPP Cibitung who live in RW 030 Tambun South. The samples consist of 100 taxpayers using an explanatory sampling method. This type of research is quantitative. The data analysis uses multiple linear regression analysis with SPSS version 25.0 program.
Based on data analysis, the results of this study indicate that partially tax audits (X1), tax sanctions (X2), and tax hostage (gijzeling) (X3) have a significant positive effect on taxpayers’ formal compliance (Y). Meanwhile simultaneously tax audits (X1), tax sanctions (X2) and tax hostage (gijzeling) (X3) have significant positive effects on taxpayers’ formal compliance of (Y), with an Adjusted R Square value of 0.444 or 44.4%.