bluuebunny/crossref_metadata_2025_split huggingface dataset:
High Occupational Physical Activity and cardiovascular risk factors in employees: a cross-sectional study
Authors: Gómez-Recasens Montse , Alfaro-Barrio Silvana , Tarro Lucia , Llauradó Elisabet , Solà Rosa 
Published: July 2020

Abstract
BackgroundThe impact of occupational physical activity (OPA) intensity, considering adults work many hours a day, on health is unknown. The present study aims to evaluate the association between the high intensity of OPA and cardiovascular risk factors of employees.MethodsA cross-sectional study was carried out in the “Fomento de Construcciones y Contratas S.A. Company” (FCC S.A. Delegation) in 2017, Spain. The intensity of OPA of each employee was classified by work categories in low (≤ 3 METs) or high (> 3 METs). Health and lifestyle data of employees were collected on medical consultation in the workplace.ResultsAssociations were analyzed between the high intensity of OPA and cardiovascular risk factors of employees. 751 employees, 55.5% (n = 417) with high intensity of OPA. An 82.2% (n = 245) of employees with low intensity of OPA presented overweight/obesity compared with 69.0% (n = 171) with high intensity of OPA employees (p < 0.001). In men, high intensity of OPA is negatively associated with Body Mass Index (BMI) (B: -0.042, p = 0.003), waist circumference (B: -0.027, p < 0.001) waist-hip ratio (B: -5.484, p < 0.001), cholesterol (B: -0.007, p = 0.001) and triglycerides (B= -0.003, p = 0.025). In women, high intensity of OPA was positively associated with blood pressure (BP) (systolic BP: B = 0.036, p = 0.005 and diastolic BP: B = 0.040, p = 0.021).ConclusionsIn conclusion, the high intensity of OPA is associated with less cardiovascular risk factors in men, whereas women are associated with high levels of blood pressure, suggesting an influence of gender and work categories.
Abnormal B Cell Compartment Associated With Tfh Cells in Children With Henoch-schonlein Purpura
Authors: Zhang Ning , Tian Ge , Sun Yuanyuan , Pan Jing , Xu Wei , Li Zhe 
Published: July 2020

Abstract
Aim

IgA-producing B cells were found to be associated with children diagnosed with Henoch-Schonlein purpura (HSP). The present study aimed to determine whether children with HSP possess abnormal B cell subsets.
Methods

A total of 14 children diagnosed with HSP, and age- and gender-matched healthy controls were enrolled in our study. Peripheral blood mononuclear cells were isolated, and the percentage of B cells subsets and Tfh cells were determined by flow cytometry. Finally, Spearman’s correlation coefficient was used to analyze the correlation between the percentage of Tfh cells and B cell subsets.
Results

We found that the frequency of total B cells was significantly increased in children with HSP; however, the percentage of plasma cells was significantly lower in HSP children. A significant reduction in the count of naïve B cells and an increase in class-switched B cells were found in children with HSP compared with healthy controls. We observed that the expression of C-X-C chemokine receptor type 5 (CXCR5) on total CD4+ T cells and the percentage of CD4+CXCR5+ cells were significantly increased within HSP patients. Moreover, significant correlations between Tfh cells and various B cells subsets were observed.
Conclusion

Our study showed a Tfh cell-associated abnormal B cell compartment in HSP children.
O controle das plataformas digitais
Authors: Artur Karen , Moreira Cardoso Ana Claudia 
Published: July 2020

Diante da expansão das plataformas digitais sob demanda, este artigo discute os argumentos que disputam a possibilidade dessas empresas continuarem a se autodenominarem como meras intermediadoras entre consumidores e prestadores de serviços independentes. A partir da abordagem sobre a construção social dos direitos, analisamos algumas experiências judiciais internacionais e, especialmente, do Brasil. Observamos que, apesar do gerenciamento que tais empresas-plataformas têm sobre os trabalhadores, há decisões judiciais que aceitam o discurso das mesmas, distanciando-se, assim, das ações que visam denunciar a insegurança provocada por essas relações e a imposição de um modelo de organização do trabalho à margem da legislação social. Com isso, contribuem para o fortalecimento da autoridade de grandes corporações.
Palavras-chave: plataformas digitais sob demanda; uberização; subordinação; decisões judiciais; regulação do trabalho.
A arte performativa do Passinho foda: 2008-2018
Authors: Bacal Tatiana , DOMINGOS EMÍLIO 
Published: July 2020

Resumo
Este artigo tem por objetivo uma etnografia de um vídeo que viralizou e se tornou histórico, o Passinho foda, postado em 2008 por um rapaz de 16 anos, numa lan house do subúrbio carioca localizada no bairro de Pilares. Partindo do conceito de ‘arte como mediação’ de A. Hennion, de ‘arte como agência’ de A. Gell e de uma ‘antropologia no som’ de S. Feld, propomos analisar o caráter inventivo da performance digital do passinho, que inclui criação, produção, dança, postagem, som e imagem.

Palavras-chave: dança urbana, som, imagem, internet, performance, criatividade
Trajetórias Musicais
Authors: Bento Ricardo 
Published: July 2020

Neste trabalho de base etnográfica acompanho diversos jovens músicos que aprenderam a tocar no contexto institucional português da Orquestra Geração, um projeto de inclusão social através da música que se inspirou nas orquestras infantis e juvenis do El Sistema, da Venezuela. Desse modo, a partir desta plataforma comum, irei observar como as redes sociabilidades musicais de alguns destes jovens músicos criam a partir das interações no espaço público das ruas de Lisboa, uma ‘micro banda de metais’ surgida das intensas relações de interconhecimento, aspirações e sonhos coletivos. Nesse sentido, pretendo analisar a integração artística, as trajetórias musicais e a vida social – de jovens músicos empenhados em manifestar-se cívica e culturalmente na esfera pública da cidade.
Palavras Chave: trajetórias musicais; Lisboa; Alta Cena; processos cooperativos; democratização cultural
Turismo penitenciário e arranjos institucionais de mercado
Authors: Luz Chikadze Thamires , Da Silva Mazon Marcia 
Published: July 2020

A partir de pesquisa realizada em um município do extremo oeste do estado de São Paulo e convertido em complexo penitenciário, foi possível analisar as especificidades do sistema prisional paulista mediante o que se configurou como turismo penitenciário. O objetivo do artigo é analisar à luz da Sociologia Econômica os efeitos do encarceramento em massa a partir do recorte de mercado. O método consistiu em etnografia e entrevistas semi-estruturadas. A pesquisa conclui que o fluxo das visitantes, identificadas pela categoria nativa mulher de preso, reconverte não só o comércio local como já observado por outras pesquisas como igualmente seus significados, conforme observa Zelizer. Se os presos situam-se num lugar a parte, a política de interiorização dos presídios e sua respectiva dinâmica de mercado inserem as suas famílias num lugar a parte e aprofundam desigualdades.
Palavras-chave: Prisões. Turismo penitenciário. Estado. Mercado. Consumo.
Antimicrobial Potentials, Phytochemical Screening and Determination of Bioactive Compounds from Three Indian Folk Medicinal Plants
Authors: Vanitha V. , Vijayakumar S. , Rajalakshmi S. 
Published: July 2020

Background:
Globally, multidrug resistance has increased in both the society and health
care systems related to bacterial infections which is impaired due to massive antimicrobial treatments.
Therefore, we need efficient, non-toxic compounds from plant-based alternatives. The aim
of the present study is to investigate the antimicrobial efficacy of leaf extracts with various solvents
of Aegle marmelos, Plumbago zeylanica and Rhinacanthus nasutus against human pathogenic
organisms.

Methods:
Antimicrobial properties of various extracts of A. marmelos, P. zeylanica and R. nasutus
were investigated against human pathogenic organisms such as Acinetobacter baumannii, Salmonella
enteriditis, Bacillus cereus, Streptococcus pneumonia, Mycobacterium tuberculosis and
Aspergillus fumigatous by agar well diffusion method. Minimum Inhibitory Concentration (MIC),
Minimum Bactericidal / Fungicidal Concentration (MBC/MFC) values were also evaluated by the
microdilution method and the phytochemicals and functional groups using HPLC, GC-MS and FTIR
analysis were identified.

Results:
Ethyl acetate leaf extract of P. zeylanica showed better antimicrobial activity against the
tested pathogens, especially for S. pneumoniae (40 mm) followed by ethyl acetate extract of R. nasutus
(36 mm) against S. pneumoniae. While the least inhibition zone was observed for the aqueous
extract of P. zeylanica against S. enteritis (10 mm). The MIC value ranged from 3.75 μg/ml to
60 μg/ml and MBC/MFC 7.5 μg/ml to 60 μg/ml. Phytochemical analysis exhibited the presence of
alkaloids, steroids, saponins, flavonoids, tannins, terpenes, phenolics and cardiac glycoside in all
samples of selected plant extracts. Tannins, phenolics and glycoside were found only in the ethyl
acetate extract of P. zeylanica. HPLC and GC-MS analysis of ethyl acetate leaf extract of P. zeylanica
produced ten major peaks thus exhibiting eleven compounds respectively. The chemical nature
of the leaf extract was analyzed by the FT-IR spectrum.

Conclusion:
Ethyl acetate leaf extract of P. zeylanica showed better antimicrobial activity than
other extracts and even standard drugs. Therefore, this plant could be further considered for advanced
research to identify active biomolecules in developing antimicrobial drugs.
A Seven-layered Model Architecture, Network Model, Protocol Stack, Security, Application, Issues and Challenges in Internet of Vehicle
Authors: Alam Intyaz , Kumar Sushil , Kashyap Pankaj Kumar 
Published: July 2020

Background:
Recently, the Internet of Things (IoT) has brought various changes in the
existing research field by including new areas such as smart transportation, smart home facilities,
smart healthcare, etc. In smart transportation systems, vehicles contain different components to access
information related to passengers, drivers, vehicle speed, and many more. This information can
be accessed by connecting vehicles with the Internet of Things leading to new fields of research
known as Internet of Vehicles. The setup of the Internet of Vehicle (IoV) consists of many sensors
to establish a connection with several other sensors belonging to different environments by exploiting
different technologies. The communication of the sensors faces a lot of challenging issues. Some
of the critical challenges are to maintain security in information exchanges among the vehicles, inequality
in sensors, quality of internet connection, and storage capacity.

Objective:
To overcome the challenging issues, we have designed a new framework consisting of
seven-layered architecture, including the security layer, which provides seamless integration by
communicating with the devices present in the IoV environment. Further, a network model consisting
of four components such as Cloud, Fog, Connection, and Clients has been designed. Finally, the
protocol stack which describes the protocol used in each layer of the proposed seven-layered IoV
architecture has been shown.

Methods:
In this proposed architecture, the representation and the functionalities of each layer and
types of security have been defined. Case studies of this seven-layer IoV architecture have also been
performed to illustrate the operation of each layer in real-time. The details of the network model
including all the elements inside each component have also been shown.

Results:
We have discussed some of the existing communication architectures and listed a few challenges
and issues occurring in present scenarios. Considering these issues, we have developed the
seven-layered IoV architecture and the network model with four essential components known as the
cloud, fog, connection, and clients.

Conclusion:
This proposed architecture provides a secure IoV environment and provides life safety.
Hence, safety and security will help to reduce the cybercrimes occurring in the network and thereby
provide good coordination and communication of the vehicles in the network.
Development of a Web-Based Resource for Parents of Young Children Newly Diagnosed With Autism: Participatory Research Design
Authors: Rabba Aspasia Stacey , Dissanayake Cheryl , Barbaro Josephine 
Published: July 2020

BackgroundThe internet provides an ideal avenue to share information, advice, and support regarding autism. However, many websites lack quality control and rarely provide a one-stop resource for families to access necessary, evidence-based information.ObjectiveThis study aims to use participatory action research (PAR) with end users (ie, parents) and clinicians to develop a web-based resource (Pathways Beyond Diagnosis) to improve timely access to quality, evidence-based information, and support for families after their child is diagnosed with autism.MethodsThe PAR approach involves 4 phases: (1) cooperative researcher-stakeholder planning, (2) cooperative researcher-stakeholder–based action, (3) stakeholder observation, and (4) cooperative researcher-stakeholder reflection. A total of 15 participants (parents, n=3; clinicians, n=9; and researchers, n=3) attended individual or group participatory design workshops. This was followed by the translation of knowledge and ideas generated during the workshops to produce mockups of webpages and content, rapid prototyping, and one-on-one consultations with end users to assess the usability of the website developed.ResultsA total of 3 participatory design workshops were held with the participants, each followed by a knowledge translation session. At the end of the PAR cycle, an alpha prototype of the website was built and a series of one-on-one end user consultation sessions were conducted. The PAR cycle revealed the importance of 6 key topic areas (understanding autism, accessing services, support, gaining funding, putting it all together, and looking into the future) associated with the time of diagnosis, which were incorporated into the beta version of the website.ConclusionsThe development of the Pathways Beyond Diagnosis website using PAR ensures that families have ready access to practical and evidence-based information following a young child’s diagnosis. The website guides families to access relevant, reputable, and evidence-based information in addition to summarizing key challenges encountered after diagnosis (ie, grief, sharing the diagnosis) and the importance of self-care.
FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF DONEPEZIL HYDROCHLORIDE
Authors: KUMARI P. V. KAMALA , RAO Y. SRINIVASA 
Published: July 2020

Objective: The present study was aimed to develop the formulation and in vitro evaluation of Orodispersible tablets by wet granulation method using Donepezil HCl as a model drug to enhance patient compliance.
Methods: In the wet granulation method, a mixture of microcrystalline cellulose and hydroxypropyl methylcellulose were used along with superdisintegrants, i.e., croscarmellose sodium and crospovidone. The prepared granules were subjected to both pre and post-compression evaluation parameters including; FTIR spectroscopy, micromeritics properties, tablet weight variation, hardness, friability, drug content, disintegration time and in vitro drug release.
Results: FTIR studies indicated that there was nointeraction between the drug and the excipients used. The formulation containing high concentration of crospovidone and mixture as the best formulation F2 based on in vitro drug release characteristics of tablet formulation.
Conclusion: The results of this work suggested that orodispersible tablets of Donepezil hydrochloride with rapid disintegration time, fast drug release and good hardness can be efficiently and successfully formulated by wet granulation method.
FORMULATION AND EVALUATION OF ANTI-ACNE GEL CONTAINING MURRAYA KOEINIGII EXTRACT
Authors: ROY SWARNALI , BOSE SANKHADIP , SARKAR DHRUBAJYOTI , MANDAL SANJIT , SARKAR SIPRA , MANDAL SUDIP KUMAR 
Published: July 2020

Objective: Acne, one among the very fashionable socially distressing skin conditions created by Propionibacterium acne have generally been treated by antibiotics. Within the light of the growing threat of antibiotic resistance, natural plant products are applied as a safer alternative. Keeping the very fact in the background, during this research work, the formulation of gel from the extracts of Murraya koeinigii leaves are prepared and evaluated as an anti-acne drug.
Methods: The fresh leaf extracts were subjected to phytochemical and antimicrobial screening. Minimum Inhibitory Concentration (MIC) decided. Gel formulation of the extracts was developed and evaluated. The manufactured formulations were subjected to In vitro antibacterial activity against P. acnes, S. epidermidis and S. aureus. The marker compound, clindamycin, in herbal anti-acne preparation, was kept for the comparison with the zones of inhibition for antibacterial activity.
Results: Anti-acne property was explored with the help of a standard curve and by comparing diffusion profiles by taking clindamycin as a reference.
Conclusion: From the present study it can be concluded that addition of permeation enhancer in the test formulation will improve the diffusion profile and thus it was designed to add permeation enhancer.
CORRELATION BETWEEN ESTRADIOL SERUM LEVELS WITH XEROSTOMIA INVENTORY SCORE ON MENOPAUSAL WOMEN
Authors: PARINDA ISTIA ASRI , SIREGAR MUHAMMAD FIDEL GANIS , HARTONO HANUDSE , SITEPU MAKMUR , MUNTHE INDRA G. , EDIANTO DERI , EYANOER PUTRI C. 
Published: July 2020

Objective: Menopause is a condition of permanent cessation of menstruation for 12 consecutive months. This occurs due to the loss of follicular ovarian activity so that estrogen levels decrease in the body. Menopause can occur at various ages, where the average age of menopause is 51-55 y. Menopause can affect oral tissues as well as other organ systems and cause xerostomia. Some of the symptoms of xerostomia include burning feelings, taste abnormalities, dysarthria, dysphagia, dysgeusia, and halitosis.
Methods: This study uses a case series design to assess the correlation between estradiol levels and the incidence of xerostomia in menopausal women. The incidence of xerostomia using the Xerostomia Inventory (XI) Score. This research was conducted in several places, namely H. Adam Malik General Hospital Medan and the hospital network of the Department of Obstetrics and Gynecology, Faculty of Medicine, University of Sumatra Utara. The study population was all postmenopausal women at the H. Adam Malik General Hospital in Medan and the Obgyn FK USU network hospital that met the study inclusion-exclusion criteria. This research was conducted in February with a minimum sample of 38 people.
Results: In this study, 38 samples were obtained. Based on the results of the study, it was found that the most age groups were in the range of 56-60 y, the duration of menopause in the 5-10 y group, and the highest Body Mass Index (BMI) was obesity. The mean value of estradiol in menopausal women was 23.61±8.37 pg/ml; the mean value of XI score in menopausal women was 24.29±9.44. The correlation of estradiol levels and XI scores in menopausal women is a strong negative correlation that is-0.651 (p value<0.05). Correlation value of XI score and obesity in menopausal women is a low positive correlation with r = 0.342 (p value<0.05) while the value of correlation XI score with menopausal women who are not obese is a strong positive correlation with r = 0.793 (p value<0, 05).
Conclusion: Changes in the oral cavity are caused by aging and hypoestrogenism. The mean age of postmenopausal women was 56.98±4.35, with a mean BMI of 28.24±4.41. Estradiol levels in menopausal women are lower than women of reproductive age in each phase of the menstrual cycle. Significant reduction in estrogen production during menopause causes a decrease in salivary flow, leading to hyposalivation and symptoms of xerostomia.
Pembinaan Terhadap Narapidana Lanjut Usia Di Lapas Kelas II A Denpasar
Authors: Pradipta I Wayan Diva Adi , Sukadana I Ketut , Karma Ni Made Sukaryati 
Published: July 2020

Lembaga Pemasyarakatan merupakan salah satu lembaga yang menegakkan hukum dalam hal pembinaan yang dilakukan terhadap para narapidana dimana segala jenis aturan yang dilakukan di dalam Lembaga Pemasyarakatan diatur dalam Undang-Undang Nomor 12 Tahun 1995 tentang pemasyarakatan. Adapun rumusan masalah yang penulis kemukakan yaitu, (1) Bagaimana proses pembinaan narapidana lanjut usia di Lapas Kelas IIA Denpasar menurut UU No.12 Tahun 1995 Tentang Pemasyarakatan. (2) Apakah upaya penyelesaian terhadap kendala yang dihadapi dalam melakukan pembinaan pada narapidana lanjut usia di Lapas Kelas IIA Denpasar. Penelitian ini menggunakan metode empiris dengan mengumpulkan data melalui wawancara di lapangan. Penelitian ini dilakukan di Lembaga Pemasyarakatan Kelas II A Denpasar yang terletak di daerah Kerobokan Kabupaten Badung. Hasil penelitian di lapangan didapat bahwa di Lembaga Pemasyarakatan yang menampung 1684 narapidana dengan klasifikasi 7 orang narapidana anak, 1663 orang narapidana dewasa serta 14 orang narapidana lansia ini telah memberikan perlakuan khusus kepada narapidana yang sudah lanjut usia karena para narapidana yang sudah lanjut usia tidak memiliki kemampuan yang cukup untuk melakukan segala kegiatan pembinaan yang seharusnya dilakukan, namun tidak ada peraturan khusus yang mengatur secara detail terkait hal tersebut. Memberikan perlakuan khusus dan membentuk aturan mengenai tata cara pembinaan terhadap narapidana yang sudah lanjut usia merupakan langkah yang wajib dilakukan agar terciptanya proses pembinaan terhadap para narapidana lanjut usia yang sesuai dengan kondisi narapidana lanjut usia itu sendiri.