bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geological mapping of coastal and offshore Japan (by GSJ-AIST): collecting and utilizing the geological information
Authors: Arai Kohsaku 
Published: June 2020

Abstract
Devastating earthquakes and tsunamis capable of causing catastrophic damage to human societies and economies have frequently occurred on and around the Japanese islands. Because Japan is a long and narrow island arc in the Pacific Ocean located at the junction of four plates (the Eurasian and Philippine Sea Plates in the SW and the North America and Pacific Plates in the NE), it has probably suffered the highest number of earthquake and tsunami events anywhere in the world. Hence, geological and geoinformation investigations are supremely important, not only for understanding the geological development of Japan but also for forecasting the risks associated with geohazards and securing the safety of human lives and infrastructures. For these reasons, the Geological Survey of Japan, National Institute of Advanced Industrial Science and Technology (GSJ-AIST) has been conducting marine geological surveys since 1974 and, as of the end of 2019, produced a Marine Geology Map Series consisting of 90 geological maps. In addition, a coastal zone research project that aims to connect marine, coastal and land area geoinformation seamlessly was launched in 2008 to survey areas that have not yet been investigated, and six maps of geologically distinct areas have already been published based on that collected data.
Evaluation of Clinical Practices Related to Variants of Uncertain Significance Results in Inherited Cardiac Arrhythmia and Inherited Cardiomyopathy Genes
Authors: Muller Reka D. , McDonald Thomas , Pope Kathleen , Cragun Deborah 
Published: June 2020

Background:
Increasing use of genetic tests have identified many variants of uncertain significance (VUS) in genes associated with inherited arrhythmias and cardiomyopathies. Evaluation of clinical practices, including medical management recommendations for VUS patients and their families, is important to prevent over- or under-treatment that may result in morbidity or mortality. The purpose of this study is to describe practices related to VUS results including information and medical management recommendations providers give patients and their families.

Methods:
An anonymous online survey was distributed to genetic counselors (GCs) and cardiologists who have seen at least one patient for inherited arrhythmias or cardiomyopathies. The survey explored providers’ confidence in counseling, explanation of VUSs, topics covered before and after genetic testing, and clinical recommendations using a hypothetical scenario maximizing uncertainty with an unclear clinical and molecular diagnosis. Descriptive statistics were calculated, and median confidence and likelihood of making various medical recommendations were compared across provider type.

Results:

Providers (N=102) who completed the survey included 29 cardiovascular GCs, 50 GCs from other specialties, and 23 cardiologists. GCs feel more confident than cardiologists counseling about VUS results (
P
<0.001); while both cardiovascular GCs and cardiologists feel more confident than other GCs in providing input regarding medical management recommendations (
P
=0.001 and
P
=0.01, respectively). Cardiologists were more likely than cardiac GCs to recommend clinical testing for family members even though testing in the scenario is expected to be uninformative.

Conclusions:
These findings illustrate how the expertise of different providers may impact decision processes, suggesting the need for interdisciplinary clinics to optimize care for challenging cases.
The Trouble with Rubbers: A History of Condoms in Modern China
Authors: Mellors Sarah 
Published: June 2020

Abstract
In recent years, public health officials and scholars have voiced their concerns about comparatively low condom use in China, citing high rates of abortion and the growing HIV/AIDS crisis. By examining condom use through the lenses of gender and the history of medicine, this article traces heterosexual condom consumption in China from the early twentieth century to the present and situates contemporary attitudes toward condoms within long-term contraceptive patterns. Rather than simply taking for granted the role that men play in family planning decisions, this research takes men and masculinity as a central focus. An eye to the past reveals numerous historical obstacles to condom use, as well as an enduring aversion to condoms grounded in fears of reduced male sexual pleasure, and the gendered assumption that birth control is the sole responsibility of women. Analyzing evolving perceptions of condoms sheds light on constructions of sexuality, gender relations, and the roles of the state, society, and the individual in contraceptive decision-making in China.
High prevalence of diseases in two invasive populations of red-eared sliders (Trachemys scripta elegans) in southwestern Spain
Authors: Hidalgo-Vila Judit , Martínez-Silvestre Albert , Pérez-Santigosa Natividad , León-Vizcaíno Luis , Díaz-Paniagua Carmen 
Published: June 2020

Abstract
Non-native turtles are susceptible to pathogenic infections that may be transmitted to native species. We performed hematological, biochemical, histopathological, and microbiological analyses in two invasive populations of red-eared sliders (Trachemys scripta elegans), which were living alongside native turtle species in southwestern Spain. The red-eared sliders that were captured had a healthy external appearance. However, the histopathological analyses revealed that up to 88% of these turtles had internal pathologies. The most common were hepatic lipidosis and chronic nephritis, which frequently co-occurred with each other or with pulmonary or pancreatic lesions. A high proportion of turtles were susceptible to infections caused by common bacteria in these habitats. We detected Herpesvirus, Mycoplasma spp. and more than 18 Gram-negative bacteria. The high prevalence of disease recorded in the two populations suggests that red-eared sliders are poorly suited to the conditions in their non-native range.
Iʿtibārī Concepts in Suhrawardī
Authors: Kaukua Jari 
Published: June 2020

Abstract
Shihāb al-Dīn al-Suhrawardī (d. 587/1191) famously criticised the central concepts of Avicennian metaphysics as merely mind-dependent (or iʿtibārī) notions. This paper aims to show that despite his critique, Suhrawardī held that these concepts are meaningful, indeed necessary for human cognition. By the same token, it is argued that their re-emergence in Suhrawardī’s ishrāqī metaphysics is not a matter of incoherence. Although the paper’s findings can be generalised to hold of all iʿtibārī concepts, mutatis mutandis, our focus is on the concept of substance, mainly because of the importance of the concept of ‘dusky substance’ in ishrāqī metaphysics.
“From the One, Only One Proceeds”
Authors: Amin Wahid M. 
Published: June 2020

Abstract
The separated intellects play a crucial but notoriously controversial role within the Neoplatonic systems of al-Fārābī and Avicenna. While both thinkers provide an array of proofs to support the existence of such immaterial substances, the most enduring of these is based on a metaphysical rule of Avicenna’s metaphysics known as the “rule of one” (qāʿidat al-wāḥid): that from the One, only one proceeds (lā yaṣdur ʿan l-wāḥid illā l-wāḥid). The following paper explores the various ways in which Avicenna defended this principle and traces their reception in the post-classical period, thereby showing how vigorously the question of emanation was debated among scholars of the later medieval period.
Does Nasal Surgery Affect Voice Outcomes? A Systematic Review with Meta-Analyses
Authors: Xiao Christopher C , Luetzenberg Friederike S. , Jiang Nancy , Liang Jonathan 
Published: June 2020

Objectives: Changes in airflow dynamics after nasal surgery may have implications on voice quality. Multiple studies have evaluated the impact of nasal surgery on voice using heterogeneous outcome measures. We aim to systematically review the impact of nasal surgery on voice quality. Methods: Our study design was a systematic review with meta-analyses. A literature search of PubMed, Ovid, Cochrane from 1997 to 2017 was performed. Inclusion criteria included English language studies containing original data on nasal surgery and voice. Two investigators independently reviewed all manuscripts and performed a comprehensive quality assessment. Meta-analysis was completed on quantitative voice measurements. Results: Of 463 identified, 19 studies with 692 patients fulfilled eligibility. Nasal surgeries performed included endoscopic sinus surgery (11/20), septoplasty (11/20), rhinoplasty (2/20), and turbinate reduction (2/20). Voice outcomes measured included nasalance (8/20), fundamental frequency (11/20), jitter (10/20), shimmer (10/20), harmonic to noise ratio (HRN) (8/20), formants (5/20), and voice handicap index (VHI) (4/20). Voice examinations were assessed preoperatively and 1 to 30 months postoperatively. Meta-analysis revealed statistically significant changes in nasalance, ( P < .01) 1 month postoperatively; there was no significant difference in nasalance at 6 months postoperatively. All other variables analyzed revealed no statistically significant differences. Five of nine studies showed majority of patients did not notice subjective change in voice after surgery, but with high heterogeneity of measurements. Conclusions: There may be a short-term increase in nasalance that resolves at longer follow-up, but there seem to be no other objective changes in voice. There may be subjective changes after surgery, but require further study to evaluate.
Minimally invasive extracorporeal circulation is a cost-effective alternative to conventional extracorporeal circulation for coronary artery bypass grafting: propensity matched analysis
Authors: Ali Jason M , Kovzel Maksym , McPhilimey Eve , Colah Simon , De Silva Ravi , Moorjani Narain 
Published: June 2020

Introduction: Minimally invasive extracorporeal circulation has developed with the aim of reducing the impact of the adverse effects associated with conventional extracorporeal circulation. The aim of this study was to compare outcomes for patients undergoing coronary artery bypass grafting using minimally invasive extracorporeal circulation with those performed using conventional extracorporeal circulation. Methods: A retrospective analysis was performed of patients undergoing minimally invasive extracorporeal circulation coronary artery bypass grafting at a single centre. 2:1 propensity matching was performed to identify control patients undergoing conventional extracorporeal circulation coronary artery bypass grafting. Outcomes were compared using univariate analysis. Results: A total of 354 patients were included in the study, with 118 patients undergoing minimally invasive extracorporeal circulation coronary artery bypass grafting. Patients were well matched on baseline characteristics. The mean logistic EuroSCORE was 3.95 ± 4.20. Operative times (3.31 ± 1.52 vs. 3.56 ± 0.73, p = 0.03) were significantly shorter in minimally invasive extracorporeal circulation cases. Patients who underwent surgery with minimally invasive extracorporeal circulation had significantly less 12-hour blood loss (322.3 ± 13.2 mL vs. 380.8 ± 15.2 mL, p < 0.01). Correspondingly, a significantly lower proportion of patients were transfused (25.8% vs. 36%, p = 0.04), and the mean number of red blood cells transfused was lower (0.45 ± 0.95 vs. 0.97 ± 2.13, p = 0.01). Similarly, the number of coagulation products administered was lower (0.161 ± 0.05 vs. 0.40 ± 0.09, p = 0.05). There was a significantly lower incidence of acute kidney injury (11.0% vs. 19.9%, p = 0.03). Minimally invasive extracorporeal circulation was associated with a £679.50 cost saving per patient. Discussion: Minimally invasive extracorporeal circulation for coronary artery bypass grafting is associated with a reduced requirement for blood transfusion, reduced incidence of acute kidney injury and a significant cost saving. Minimally invasive extracorporeal circulation should be considered as an adjunct for all patients undergoing coronary artery bypass grafting.
Variation in the Factors Associated With Diet Quality of Children Aged 6 to 23 Months in Low and High Agroecological Zones of Rongai Subcounty, Kenya
Authors: Kemboi Sharon , Mungiria-Mituki Dorothy , Ramkat Rose , Termote Celine , Covic Namukolo , Cheserek Maureen Jepkorir 
Published: June 2020

Background: Adequate quality complementary diets and appropriate feeding practices are important for proper growth and development of young children. Objective: To assess factors associated with diet diversity, meal frequency, and acceptable diet of children aged 6 to 23 months in two agroecological zones of Rongai subcounty, Kenya. Methods: A cross-sectional study was conducted among 384 mothers/caregivers with children aged 6 to 23 months. A structured questionnaire was used to assess sociodemographic characteristics and child feeding practices. Diet diversity, meal frequency, and acceptable diet were derived from a 24-hour recall of child’s food intake. Factors associated with diet quality were determined using binary logistic regression. Results: Mean child diet diversity score was 3.54 ± 1.0 of 7 food groups, with 56.8% of the children achieving minimum dietary diversity. A majority of the children (81.8%) received minimum meal frequency (MMF), with significant ( P < .05) difference between low (91.1%) and high (75.2%) agricultural potential areas. Children who received minimum acceptable diet (MAD) were only 34.1%. Mother/caregiver education level positively ( P < .05) associated with minimum diet diversity in low potential area (adjusted odds ratio [AOR] = 3.79, 95% CI: 1.47-9.75) and with MAD in high potential area (AOR = 1.87, 95% CI: 1.01-3.46). Other factors associated with MDD, MMF, and MAD included household income and slow feeding in low potential area, and child gender and active feeding in high potential area. Conclusion: There is a variation in factors associated with diet quality and child feeding practices in different agroecological zones. Therefore, nutrition education and behavior change communication interventions aimed at improving child nutrition should be context-specific.
Parents’ Perceptions of the Acceptability of Evidence-Based Interventions to Support Transition From Neonatal to Rehabilitation Services
Authors: Yamada Janet , Ballantyne Marilyn , Kron Amie T. , Sidani Souraya 
Published: June 2020

Background Parents of children born preterm with a disability often experience profound psychological distress with transition from neonatal to rehabilitation services. Four interventions were found effective to support parents throughout this critical transition period whereby parental stress can threaten the child’s development. Purpose To examine parents’ perceptions of the acceptability of four evidence-based interventions to support their transition. Methods A quantitative design using survey methods was employed with 24 parents with experience in transition to rehabilitation services. Each participant rated the acceptability of the interventions using the Treatment Perception and Preference scale. Descriptive statistics and repeated measures analysis of variance were used for data analysis. Results Mean overall acceptability scores differed across the four interventions ( p = .042); the difference was of moderate size (η2 = .11). Parents perceived psychoeducation and narrative therapy as most acceptable, followed by website consultation with healthcare providers and parent support program, then parent self-help program. Conclusions Psychoeducation and narrative therapy should be accessible to parents experiencing transition from neonatal to rehabilitation services.
Enhancing the quality of supervision: description and initial outcomes of a blended-learning approach to RANZCP supervisor accreditation
Authors: Parker Stephen , Warren Nicola , Hamilton Sarah , Cabral Sidney , Cutbush Jimsie 
Published: June 2020

Objective: Evaluation of a blended learning adaptation of the accreditation process for supervisors in the Royal Australian and New Zealand College of Psychiatrists’ (RANZCP) Competency-Based Fellowship Program. Method: The adaption of the accreditation process is described, and a mixed-methods approach was taken in its evaluation. Descriptive statistics are presented for participant responses to and engagement with interactive workshop elements. The Wilcoxon signed ranks test was applied to examine the change in participants’ confidence in their understanding of the expectations of a supervisor at the commencement and conclusion of the workshop. Free text evaluative responses were subject to qualitative content analysis. Results: Most participants expressed a preference for the blended learning workshop format and indicated that live polling improved the learning experience. Additionally, participants expressed greater confidence in their understanding of the expectations of the supervisor role following workshop completion. Conclusions: The blended learning approach to supervisor training was preferred by participants and may provide a model to be adopted by other training committees and institutions.
Total or subtotal full thickness recipient bed cut to repair donor–recipient curvature disparity in cases of DM rupture with manual DALK
Authors: Sarnicola Enrica , Sarnicola Caterina , Cheung Albert Y , Panico Edoardo , Panico Claudio , Sarnicola Vincenzo 
Published: June 2020

Purpose: To report how to manage a specific type of Descemet’s membrane (DM) rupture during manual DALK with a concurrent donor–recipient disparity of curvature. Methods: Case report of two patients that had DM rupture during manual DALK with a concurrent donor–recipient disparity of curvature; the recipient bed was flatter (post-infectious scar, case 1) and steeper (keratoglobus, case 2) than the donor. Preoperative diagnosis, clinical exam, and best spectacle correct visual acuity (BSCVA) have been reported. A subtotal full-thickness circular cut of the recipient bed was performed to resolve a persistent double AC in case 1 (recipient flatter than donor). A total full-thickness circular cut of the recipient bed, creating a graft made by a DALK allograft and a “DSEK autograft,” was performed to avoid a refractory double AC in case 2 (recipient steeper than donor). Evaluated outcomes included postoperative BSCVA, endothelial cell count (ECC), graft clarity, rejection, and presence/absence of double AC. Results: Surgery was successful in resolving/avoiding double AC. VA improved in both cases. No episodes of rejection were recorded. Graft remained clear at the last follow-up (6 years for case 1 and 4 years for case 2). Conclusion: The existence of a donor–recipient curvature disparity should be investigated as a possible underlying mechanism of refractory double AC. Total or subtotal full thickness recipient bed cut may be considered to repair donor–recipient curvature disparity in cases of DM rupture occurring during manual DALK. Repairing the DM rupture and avoiding a conversion to PK in high-risk transplant cases are crucial.
Effects of topical pilocarpine on ocular growth and refractive development in rabbits
Authors: Tong Liyang , Cui Dongmei , Zeng Junwen 
Published: June 2020

Purpose: This study aimed to investigate whether topical pilocarpine affects ocular growth and refractive development as well as the underlying biochemical processes in early eye development in rabbits. Methods: Twenty three-week-old New Zealand white rabbits were treated with 0.5% pilocarpine in the right eye for 6 weeks. The left eyes served as contralateral controls. The effects of pilocarpine on refractive error, corneal curvature and ocular biometrics were assessed using streak retinoscopy, keratometry, and A-scan ultrasonography, respectively. Eyeballs were enucleated for histological analysis. The ciliary body and sclera were homogenized to determine the mRNA and protein expression levels of five subtypes of muscarinic receptors. Results: Compared to control eyes, pilocarpine-treated eyes exhibited approximately −1.63 ± 0.54 D myopia accompanied by a 0.11 ± 0.04 mm increase in axial length (AL) ( p < 0.001, respectively). The anterior chamber depth (ACD) was reduced, whereas the lens thickness (LT) and vitreous chamber depth (VCD) increased ( p < 0.001, respectively). Corneal curvature decreased over time but was not significantly different between treated and control eyes. The mRNA and protein expression levels of five subtypes of muscarinic receptors were upregulated in the ciliary body and downregulated in the sclera. Conclusions: Based on these results, pilocarpine can induce myopic shift, increase LT, elongate VCD and AL, and reduce muscarinic receptor expression in the sclera early in development. These changes raise the possibility that pilocarpine may promote axial elongation in ocular development and facilitate the emmetropization of hyperopic eyes.
Aerobic Exercise Interventions for Patients in Opioid Maintenance Treatment: A Systematic Review
Authors: Jake-Schoffman Danielle E , Berry Meredith S , Donahue Marissa L , Christou Demetra D , Dallery Jesse , Rung Jillian M 
Published: June 2020

Background: Opioid maintenance treatment (OMT) is the standard for treatment of opioid use disorder, but some individuals on OMT experience disrupted sleep, heightened sensitivity to pain, and continued relapse to non-medical opioid use. An adjunctive treatment that has potential to address these shortcomings of OMT is aerobic exercise. Objective: The aim of the present review was to identify and evaluate components of aerobic exercise interventions targeting OMT patients. Methods: For this PROSPERO-registered review (ID CRD42020139626), studies were identified via electronic bibliographic databases, funded research ( NIH RePORTER) and clinical trials databases ( ClinicalTrials.gov), and reference sections of relevant manuscripts. Studies that evaluated the effects of an aerobic exercise intervention using a comparison condition or pretest-posttest design in adult OMT patients were included. Results: Of 2971 unique records, three primary studies and one supplemental manuscript comprised the final sample. All studies were randomized trials involving supervised exercise interventions enrolling small samples of middle-aged OMT patients. Exercise interventions included a variety of aerobic and non-aerobic activities (e.g. flexibility exercises), and none controlled the dose of aerobic exercise. Few studies used objective measures of physical activity or cardiorespiratory fitness and there were no significant effects of adjunctive exercise on substance use outcomes, but tests of the latter were likely underpowered. Conclusions: Though early in the accumulation of evidence, interventions targeting aerobic exercise for OMT patients appear feasible, acceptable to patients, and beneficial. Longer-term studies that employ larger samples, include assessments of behavioral and biological mechanisms of change, more rigorous measurement of physical activity, and controlled doses of aerobic activity are warranted.