bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate change and trend analysis of temperature: the case of Addis Ababa, Ethiopia
Authors: Alemu Zinabu Assefa , Dioha Michael O. 
Published: October 2020

AbstractBackgroundThis paper presents the trend analysis of temperature and the effect of climate variation in the city of Addis Ababa, Ethiopia. The paper seeks to provide up-to-date information for the better management of climate change in the city. The analysis is based on the temperature difference in the city over two stations—Bole and Entoto. The overall purpose of this study is to investigate the possible trend of temperature variation as well as the effect of climate change in the study area.MethodThe Mann-Kendall (MK) trend test and Sen's slope estimate were employed to find the nature of the temperature trend and significance level in the city.ResultsIt was found that the MK2/MK3 statistic (Z) value for minimum, maximum and average temperatures for Bole station are 6.21/5.99, 2.49/2.6, and 6.09/6.14 respectively. The positive Kendall's Z value shows an upward trend and implies an increasing trend over time. This indicates a significant increase in the trend at a 5% level of significance since the significance level (alpha) is greater than the computed p-value (0.05 > p-values (0.0001)). Whereas for Entoto station, the MK1 statistic (Z) results are 1.64 for minimum, while the MK2/MK3 static (Z) are 0.71/0.65 for the maximum, and 0.17/1.04 for average temperature, and this positive value shows an indicator of an increasing trend. However, the increase is not significant at the 5% significant level since the computed p-value is larger than the significant level (alpha = 0.05).ConclusionsThere is a tendency of temperature increments in Bole station. This could be due to the influence of climate change which can lead to weather extremes in the capital city. Therefore, the study recommends that the variability of temperature needs further monitoring technique, and there is a need to consider the increasing temperature trend to minimize its effects on human health.
High-volume image-guided injection in the chronic recalcitrant non-insertional patellar tendinopathy: a retrospective case series
Authors: Nielsen Torsten Grønbech , Miller Lene Lindberg , Mygind-Klavsen Bjarne , Lind Martin 
Published: October 2020

Abstract
Purpose
To evaluate if High-volume Image-guided Injection (HVIGI)-treatment for chronic Patellar tendinopathy (PT) improve function and reduce pain at 16-months follow-up.

Methods
Patients with resistant PT who failed to improve after a three-month eccentric loading program were included in the study. Maximal tendon thickness was assessed with ultrasound. All patients were injected with 10 mL of 0.5% Marcaine, 0.5 mL Triamcinolonacetonid (40 mg/mL) and 40 mL of 0.9% NaCl saline solution under real-time ultrasound-guidance and high pressure. All outcome measures were recorded at baseline and at 16 months. A standardised Heavy Slow Resistance rehabilitation protocol was prescribed after HVIGI-treatment. Clinical outcome was assessed with the Victorian Institute of Sports Assessment-Patella tendon questionnaire (VISA-P) and statistically analyses were performed.

Results
The study included 28 single treatment HVIGI procedures in PT in 23 patients (19 men, 4 women) with a mean age of 30.3 (range 19–52). The mean duration of symptoms before HVIGI was 33 months. The baseline VISA-P score of 43 ± 17 (range 15–76) improved to 76 ± 16 (range 42–95) after 16 months (p < 0.01). Of the 28 HVIGI procedures 12 patients (15 PT) were not satisfied after the initial HVIGI procedure. Of these, 5 patients (5 PT) had additional HVIGI, 2 patients (2 PT) had corticoid injection and 6 patients (8 PT) needed surgery. Of the remaining 11 patients (13 PT), 9 patients had more than a 13-point improvement in the VISA-P score after 16 months.

Conclusions
In this retrospective case-study, only 9 patients (32%) did benefit of a single HVIGI treatment at 16-months and a 33-point significant improvement was seen on the VISA-P score.
Television Rewired: The Rise of the Auteur Series, Martha P. Nochimson (2019)
Authors: Hills Matt 
Published: October 2020

Review of: Television Rewired: The Rise of the Auteur Series, Martha P. Nochimson (2019)
Austin: University of Texas Press, 313 pp.,
ISBN 978-1-47731-895-9, p/bk, $34.95

Twin Peaks: TV Milestones Series, Julie Grossman and Will Scheibel (2020)
Detroit: Wayne State University Press, 111 pp.,
ISBN 978-0-81434-622-8, p/bk, £22.99
Virtual screening assisted identification of small molecule against 2019 novel coronavirus protease enzyme
Authors: Sarkar Arkadeep , Shilkar Deepak , Maity Arindam , Sardar Sarmi , Debnath Sudhan , Sen Debanjan , Jayaprakash Venkatesan 
Published: October 2020

TheÂ 2019 novel coronavirus infection or COVID-19 can be designated as a global threat. Till date, there is a lack of dedicated therapeutics available against this fatal infection. In the present work, we performed structure-based drug design studies in order to identify clinically used molecules exhibiting crucial binding with 2019-coronavirus main protease enzyme. Based on ligand binding energy and interaction with essential amino acids, two molecules were selected. The stability of the complexed molecules with main protease enzyme was further studied by performing molecular dynamics simulation.
Ideas and Explanation in Early Modern Philosophy
Authors: Pearce Kenneth L. 
Published: October 2020

AbstractMalebranche argues that ideas are representative beings existing in God. He defends this thesis by an inference to the best explanation of human perception. It is well known that Malebranche’s theory of vision in God was forcefully rejected by philosophers such as Arnauld, Locke, and Berkeley. However, the notion that ideas exist in God was not the only controversial aspect of Malebranche’s approach. Another controversy centered around Malebranche’s view that ideas are to be understood as posits in an explanatory theory. Opponents of this approach, including Arnauld and Locke, held that our talk about ideas was not explanatory but instead merely descriptive: we use the word ‘idea’ to describe phenomena that we observe by reflecting on our own minds. This controversy has not received much attention from scholars, but in the present paper I will show that it was an explicit and important subject of concern for Malebranche, Arnauld, Locke, and Berkeley and that attention to this controversy can illuminate several aspects of these philosophers’ work.
Further results on Ulam stability for a system of first-order nonsingular delay differential equations
Authors: Zada Akbar , Pervaiz Bakhtawar , Alzabut Jehad , Shah Syed Omar 
Published: October 2020

AbstractThis paper is concerned with a system governed by nonsingular delay differential equations. We study theβ-Ulam-type stability of the mentioned system. The investigations are carried out over compact and unbounded intervals. Before proceeding to the main results, we convert the system into an equivalent integral equation and then establish an existence theorem for the addressed system. To justify the application of the reported results, an example along with graphical representation is illustrated at the end of the paper.
The Referral “Power” of ICC Prosecutor according to Art. 13 StICC
Authors: Liakopoulos Dimitris 
Published: October 2020

Abstract
The present work will be devoted to the power to activate the investigations of the Prosecutor according to art. 13 of the Statute of the International Criminal Court (StICC). The StICC tries to offer some coordination tools, whose correct and careful use should in principle favor a harmonious and effective interaction between the two organs (International Criminal Court (ICC) and Security Council (SC)) and avoid the emergence of conflicts. As we will try to highlight, despite these intent of the statutory provisions, the margin of discretion inevitably granted to ICC and SC in interpreting the extension of the powers recognized to them, can lead to tensions and contrasts of not easy solution.
Diversity of GPI-anchored fungal adhesins
Authors: Essen Lars-Oliver , Vogt Marian Samuel , Mösch Hans-Ulrich 
Published: October 2020

AbstractSelective adhesion of fungal cells to one another and to foreign surfaces is fundamental for the development of multicellular growth forms and the successful colonization of substrates and host organisms. Accordingly, fungi possess diverse cell wall-associated adhesins, mostly large glycoproteins, which present N-terminal adhesion domains at the cell surface for ligand recognition and binding. In order to function as robust adhesins, these glycoproteins must be covalently linkedto the cell wall via C-terminal glycosylphosphatidylinositol (GPI) anchors by transglycosylation. In this review, we summarize the current knowledge on the structural and functional diversity of so far characterized protein families of adhesion domains and set it into a broad context by an in-depth bioinformatics analysis using sequence similarity networks. In addition, we discuss possible mechanisms for the membrane-to-cell wall transfer of fungal adhesins by membrane-anchored Dfg5 transglycosidases.
Living data
Authors: Allen Barry 
Published: October 2020

Abstract
We see new technologies changing how we live, and seemingly set to do so at a rising pace. How should we describe these changes, and what exactly is changing? I discuss the theory of technical change in Simondon, On the Modes of Existence of the Technical Object. Once we understand precisely what sort of change qualifies as “technical,” we see that the changes in question today have little to do with technology as such, more with a new infrastructure for its deployment.
Myth and technology: Finding philosophy’s role in technological change
Authors: Brayford Kieran 
Published: October 2020

Abstract
In this paper, I argue that philosophy’s potential to influence technological change is impeded by the presence of two common and influential myths surrounding technology—the myth of progress and the myth of technological determinism. Such myths, I suggest, hinder philosophy’s influence by presenting a distorted image of technology—respectively, as an unqualified good, and as an entity with its own autonomous logic. Steven Pinker and Martin Heidegger are selected as influential advocates for progress and technological determinism respectively, and their work is explored in turn. The work of John Gray and of Herbert Marcuse is then employed to demythologise technology by articulating an alternative image of technology that is not just more accurate, but also more conducive to philosophical influence. Finally, the work of Hans Jonas and Luciano Floridi is used to ground the conclusion that, should philosophy wish to influence technological change, an effective method of doing so could be the articulation of ethical maxims and the supervision of their translation into a real world setting.
Form, technique and liberation: Schiller’s influence on Marcuse’s philosophy of technology
Authors: Souza Juliano Bonamigo Ferreira de 
Published: October 2020

AbstractThis article seeks to analyze the theory of technology formulated by the philosopher Herbert Marcuse (1898–1979). It shows the ways in which the author repurposes fundamental concepts of classical aesthetics in order to formulate a theory of technology aimed at liberating both nature and humanity. To this end, we argue that Marcuse mobilizes the theories of Immanuel Kant (1724–1804) and Friedrich Schiller (1759–1805). In the first part of the article, we tackle some important aspects of Kant’s and Schiller’s aesthetic theories. We begin with an analysis of Kant’sCritique of the Power of Judgment(1790), focusing on central concepts that would later be absorbed by Schiller and Marcuse. Next, we try to show the reception of theThird critiquein Schiller’sOn the Aesthetic Education of Man(1795) and this author’s contribution to aesthetic studies within political thought. In the second part, we focus on Marcuse’s work, highlighting two key moments in his analysis on technology. We show that his theory undergoes transformation and development until it reaches its stable form in the 1960s and 1970s, during which the author proposes a new theory of technology based on human aesthetic possibilities whose goal is the liberation of nature.
Influencing technological change
Authors: Pitt Joseph C. 
Published: October 2020

Abstract
The philosophy of technology is not influencing technological change because there isn’t a single philosophy of technology. Philosophers of technology should be involved in technological change because we have something valuable to offer. But before we can get involved, we have to be accepted by those effecting the changes. That means we have to acquire the credentials necessary to establish our credibility. We have to get our hands dirty.
Technologies of self-cultivation. How to improve Stoic self-care apps
Authors: Dennis Matthew 
Published: October 2020

Abstract
Self-care apps are booming. Early iterations of this technology focused on tracking health and fitness routines, but recently some developers have turned their attention to the cultivation of character, basing their conceptual resources on the Hellenistic tradition (Stoic Meditations™, Stoa™, Stoic Mental Health Tracker™). Those familiar with the final writings of Michel Foucault will notice an intriguing coincidence between the development of these products and his claims that the Hellenistic tradition of self-cultivation has much to offer contemporary life. In this article, I explore Foucault’s cryptic remarks on this topic, and argue that today’s self-care developers can improve future products by paying attention to the Hellenistic exercises of self-cultivation he identifies as especially important.
Digital whiplash: The case of digital surveillance
Authors: Dormandy Katherine 
Published: October 2020

Abstract
Digital technology is rapidly transforming human life. But our cognition is honed for an analog world. I call this the problem of digital whiplash: that the digital transformation of society, like a vehicle whose sudden acceleration injures its occupants, is too fast to be safe. I focus on the unprecedented phenomenon of digital surveillance, which I argue poses a long-term threat to human autonomy that our cognition is ill-suited to recognize or respond to. Human cognition is embodied and context-sensitive, and thus faces four problems of digital whiplash vis-à-vis digital surveillance. First is the problem of signal sparsity, that there are few if any perceptible indications of digital surveillance. Second is the problem of signal elusiveness, that the few indications there are prohibitively difficult to discover. Third is the distraction problem, that using digital technologies corrodes the cognitive abilities we need to recognize and respond to digital surveillance. Fourth is the hooking problem, that digital technologies are engineered to cultivate dependency. I address, among other objections, the idea that we choose to exchange our privacy for the use of digital technologies, so their use is in fact an expression of autonomy. The response to digital whiplash, I argue, is not to slow down the digitalization of society in its current form so that we can adapt our cognitive capacities. It is to allow ourselves the time to reflect on and debate whether digitalization, in its current form, is delivering a socially and ethically desirable future.
Artificial life and ‘nature’s purposes’: The question of behavioral autonomy
Authors: Popa Elena 
Published: October 2020

AbstractThis paper investigates the concept of behavioral autonomy in Artificial Life by drawing a parallel to the use of teleological notions in the study of biological life. Contrary to one of the leading assumptions in Artificial Life research, I argue that there is a significant difference in how autonomous behavior is understood in artificial and biological life forms: the former is underlain by human goals in a way that the latter is not. While behavioral traits can be explained in relation to evolutionary history in biological organisms, in synthetic life forms behavior depends on a design driven by a research agenda, further shaped by broader human goals. This point will be illustrated with a case study on a synthetic life form. Consequently, the putative epistemic benefit of reaching a better understanding of behavioral autonomy in biological organisms by synthesizing artificial life forms is subject to doubt: the autonomy observed in such artificial organisms may be a mere projection of human agency. Further questions arise in relation to the need to spell out the relevant human aims when addressing potential social or ethical implications of synthesizing artificial life forms.
Micro-emulsion synthesis of La1 − xCrxFeO3 nanoparticles: effect of Cr doping on ferroelectric, dielectric and photocatalytic properties
Authors: Abbas Sehrish , Bibi Ismat , Majid Farzana , Ata Sadia , Ibrahim Sobhy M. , Kamal Shagufta , Sultan Misbah , Jilani Kashif , Iqbal Shahid , Iqbal Munawar 
Published: October 2020

AbstractIn the present study, La1 − xCrxFeO3(x = 0.0, 0.3, 0.6, 0.9, 1.0) was synthesized by micro-emulsion route and characterized by X-ray Diffraction (XRD), Fourier Transform Infrared (FTIR), Scanning electron microscope (SEM), Energy-dispersive X-ray (EDX) techniques. The dielectric, ferroelectric and photocatalytic properties were investigated and compared with un-doped material. The XRD analysis revealed orthorhombic geometry of La1 − xCrxFeO3(x = 0.0, 0.3, 0.6, 0.9, 1.0), Cr was doped successfully into the lattice structure of LaFeO3and particles were spherical and in agglomerated form. The grain sizes were recorded to be 15, 16.9, 17.1, 17.65 and 18.3 (nm) for La1 − xCrxFeO3(x = 0.0, 0.3, 0.6, 0.9, 1.0), respectively. EDX analysis confirmed the purity of LaCrFeO3samples. The lattice parameters, bulk density, X-ray density, crystalline size and porosity were determined were also determined of all the La1 − xCrxFeO3samples. The dielectric constant and dielectric loss values decreased at higher frequency and Cr concentration affected the dielectric properties. The photocatalytic activity (PCA) was evaluated by degrading Congo Red (CR) dye under solar light irradiation and up to 85.43% dye degradation was achieved within 45 min of irradiation. Phyto-toxicity analysis before and after dye degradation was performed, which revealed the toxicity reduction in response of dye degradation. Results revealed that lanthanum ferrite (perovskite) doping with Cr could possibly be employed to enhance the ferroelectric, dielectric and photocatalytic properties.
Nurse students’ attitudes toward the nursing profession after witnessing workplace violence
Authors: Ayasreh Ibrahim R. , Khalaf Inaam A. 
Published: October 2020

AbstractBackgroundWorkplace violence is one of the most compelling problems facing health care sectors all over the world. The detrimental impact of workplace violence extends to affect nurse students who receive their training in clinical areas.ObjectiveThe study aimed to investigate the impact of witnessing workplace violence during clinical training on the attitudes of Jordanian nursing students toward the nursing profession.MethodsCross-sectional design was used in this study. Data were collected through electronic survey questionnaires from 131 nursing students from three nursing schools in Jordan. Attitude Scale for Nursing Profession was used to assess the participants’ attitude toward nursing profession.ResultsThe results showed that about 34% of student participants witnessed workplace violence during their clinical training. Nursing student participants who did not witness workplace violence showed significantly more positive attitude toward nursing profession than who did witness.ConclusionWitnessing workplace violence had a significant negative impact on how nursing students view nursing job.
Foodmiles: The Logistics of Food Chains Applied to Food Quality Schemes
Authors: Drut Marion , Antonioli Federico , Böhm Michael , Brečić Ruzica , Dries Liesbeth , Ferrer-Pérez Hugo , Gauvrit Lisa , Hoàng Việt , Steinnes Kamilla Knutsen , Lilavanichakul Apichaya , Majewski Edward , Napasintuwong Orachos , Nguyễn An , Mattas Konstadinos , Ristic Bojan , Schaer Burkhard , Tangeland Torvald , Maksan Marina Tomić , Csillag Peter , Török Áron , Tsakiridou Efthimia , Veneziani Mario , Vittersø Gunnar , Bellassen Valentin 
Published: October 2020

Abstract
This paper estimates the foodmiles (embedded distances) and transport-related carbon emissions of 27 Food Quality Scheme (FQS) products – Protected Designation of Origin (PDO), Protected Geographical Indications (PGI) and organic – and their reference products. It goes further than the existing literature by adopting a value chain perspective, instead of the traditional consumer perspective, and focusing on FQS products. The same methodology is applied across all the case studies. The article specifically investigates the determinants of differences between FQS and their references. FQS products travel significantly shorter distances (−30%) and generate significantly lower transport-related emissions (−23%) than conventional food products. The differences are even greater for vegetal and organic products. The relationship between distance and transport-related emissions is not exactly proportional and highlights the importance of transport modes and logistics, in particular for exports and imports. Finally, we stress the importance of the spatial distribution of the different stages in the value chains (e.g. production, processing). PDO technical specifications delimit a geographical area for production and processing, thereby limiting distances and transport-related emissions compared to conventional food products, but also compared to other types of FQS.
The use of glimepiride for the treatment of neonatal diabetes mellitus caused by a novel mutation of the ABCC8 gene
Authors: Qin Xiao , Zhong Jingzi , Lan Dan 
Published: October 2020

Abstract

Objectives
Neonatal diabetes mellitus (NDM) is a rare form of monogenic diabetes that is usually diagnosed in the first six months of life.

Case presentation
We report on a male infant with neonatal diabetes who presented with diabetic ketoacidosis at two months and 16 days. A novel homozygous missense mutation (c.259T>G) was identified in the ABCC8 gene. In this case, insulin was replaced with glimepiride at a dosage of 0.49 mg/kg/day at five months, and this achieved metabolic control and satisfactory growth as observed at follow-up.

Conclusions
This report improves our understanding of the mutational spectrum of ABCC8, which is normally associated with NDM, and shows that the treatment regimen for this condition can be successfully switched from insulin therapy to the use of sulfonylurea.