bluuebunny/crossref_metadata_2025_split huggingface dataset:
A preliminary study on seasonal variations of sediment concentrations in the inner Qiantang Estuary
Authors: Xie Dongfeng , Huang Junbao , Bo Jiang , Li Ruohua , Tang Ziwen , Lu Haiyan 
Published: September 2020

Abstract
The Qiantang Estuary is characterized by high suspended sediment concentrations, due to the world-famous tidal bore. In this study, continuous sediment concentrations has been observed in the inner Qiantang Estuary in April, June, September and November of 2018, by fixing an OBS on a floating platform. The results show that SSC have both tidally and seasonal variations, in particular influenced by the tidal bore. In summer and autumn the tidal ranges were relatively large and the time series of SSC were spike-similar. In spring and winter the tidal ranges were relatively smaller and the time series of SSC were similar to a sine/cosine curve. SSC is largest in autumn, followed by summer and winter, and smallest in spring. SSCs in the summer and autumn correlate positively with tidal range but the correlations in spring and winter are less insignificant. SSC depends mainly on the tidal range given the tidal range is large enough. Under relatively smaller tidal range, the relative importance of other factors such as river discharge, bed level changes and winds, etc., on the sediment concentrations would be increased.
Effect of Gender Roles and Workplace Violence on the Professional Quality of Life and Wellbeing at Work Among Child Protection Workers
Authors: Dufour Renaud , Juster Robert-Paul , Geoffrion Steve 
Published: September 2020

Abstract
Exposure to workplace violence puts child protection workers at risk for adverse occupational outcomes. While previous studies have identified protective and risk factors, individual differences in gender roles have yet to be explored. Moving beyond sex, the present study aims to examine the ways in which gender roles influence exposure to workplace violence, professional quality of life, and wellbeing at work among child protection workers. A randomized sample stratified by sex of 301 Canadian child protection workers (male: 15.6%, female: 84.4%) completed validated questionnaires of gender roles, professional quality of life, and wellbeing at work. We assessed mean differences using analyses of covariances controlling for clinical experience and type of work. We then assessed the moderating effect of gender roles on other variables through hierarchical multiple linear regressions. Androgyny (high masculinity and high femininity) was associated with higher scores on positive indicators of professional quality of life and wellbeing at work. However, gender roles showed no significant moderating effect on the relationship between exposure to violence, professional quality of life, and wellbeing at work. Results suggest that androgyny could be related to potential psychosocial benefits for child protection workers.
A novel, comprehensive tool for predicting 30-day mortality after surgical aortic valve replacement
Authors: Biancari Fausto , Rosato Stefano , Costa Giuliano , Barbanti Marco , D’Errigo Paola , Tamburino Corrado , Cerza Francesco , Rosano Aldo , Seccareccia Fulvia ,   for the OBSERVANT Research Group, Seccareccia Fulvia , D’Errigo Paola , Rosato Stefano , Maraschini Alice , Badoni Gabriella , Tamburino Corrado , Barbanti Marco , Santoro Gennaro , Ranucci Marco , Covello Remo Daniel , De Palma Rossana , Scondotto Salvatore , Region Sicilia 
Published: September 2020

Abstract

OBJECTIVES
We sought to develop and validate a novel risk assessment tool for the prediction of 30-day mortality after surgical aortic valve replacement incorporating a patient’s frailty.

METHODS
Overall, 4718 patients from the multicentre study OBSERVANT was divided into derivation (n = 3539) and validation (n = 1179) cohorts. A stepwise logistic regression procedure and a criterion based on Akaike information criteria index were used to select variables associated with 30-day mortality. The performance of the regression model was compared with that of European System for Cardiac Operative Risk Evaluation (EuroSCORE) II.

RESULTS
At 30 days, 90 (2.54%) and 35 (2.97%) patients died in the development and validation data sets, respectively. Age, chronic obstructive pulmonary disease, concomitant coronary revascularization, frailty stratified according to the Geriatric Status Scale, urgent procedure and estimated glomerular filtration rate were independent predictors of 30-day mortality. The estimated OBS AVR score showed higher discrimination (area under curve 0.76 vs 0.70, P &lt; 0.001) and calibration (Hosmer–Lemeshow P = 0.847 vs P = 0.130) than the EuroSCORE II. The higher performances of the OBS AVR score were confirmed by the decision curve, net reclassification index (0.46, P = 0.011) and integrated discrimination improvement (0.02, P &lt; 0.001) analyses. Five-year mortality increased significantly along increasing deciles of the OBS AVR score (P &lt; 0.001).

CONCLUSIONS
The OBS AVR risk score showed high discrimination and calibration abilities in predicting 30-day mortality after surgical aortic valve replacement. The addition of a simplified frailty assessment into the model seems to contribute to an improved predictive ability over the EuroSCORE II. The OBS AVR risk score showed a significant association with long-term mortality.
Deciphering the dynamics of a heterogeneous sea cliff using ambient vibrations: case study of the Sutta-Rocca overhang (southern Corsica, France)
Authors: Mercerat E Diego , Payeur Jean Baptiste , Bertrand Etienne , Malascrabes Marie , Pernoud Michel , Chamberland Yannick 
Published: September 2020

SUMMARYWe report here an interesting case study of dynamic characterization of a limestone sea cliff area, named the Sutta-Rocca overhang, located near the medieval town of Bonifacio (southern Corsica, France). The site belongs to an UNESCO protected area with an important number of visitors per year. Therefore, it is of particular interest to evaluate the potential rockfall hazard along the cliff. With the objective of evaluating the feasibility of an operational technique to monitor the cliff using ambient vibrations, two seismic stations were installed during six months (from 2016 November to 2017 April) in order to identify and monitor the resonant frequencies of the a priori unstable rock mass. Several techniques of classical seismic monitoring are tested on the site: single-station spectral analysis for identification of frequency peaks related to the unstable mass, relative spectral amplifications between stations and the operational modal analysis of the cliff. In particular, data analysis from a temporary campaign of two days of continuous recordings by a linear array of seismometers perpendicular to the sea cliff highlights the main characteristics of the ground motion: the overall motion of the promontory mainly in the north–south direction (perpendicular to the coast) and bending vertical and parallel to the cliff (east–west direction) at higher frequencies. The strong vertical and east–west seismic amplifications are also confirmed by the analysis of five local seismic events recorded at both semi-permanent stations. Even if ambient vibrations and seismic data analysis allows to decipher the dynamics of the Sutta-Rocca overhang, we conclude that classical seismic monitoring of just one single frequency peak with a limited number of sensors is not recommended for this particular site.
Progestin type affects the increase of heparanase level and procoagulant activity mediated by the estrogen receptor
Authors: Treger Sharon , Ackerman Shanny , Kaplan Victoria , Ghanem Shourouk , Nadir Yona 
Published: September 2020

Abstract

STUDY QUESTION
Does progestin have an effect on heparanase level and procoagulant activity?

SUMMARY ANSWER
Progestin increases the heparanase level and procoagulant activity via the estrogen receptor and the magnitude of the effect depends on the progestin type.

WHAT IS KNOWN ALREADY
Users of combined oral contraceptives (COCs) containing third- and fourth-generation progestins have a higher risk of venous thrombosis compared to those employing second-generation progestins. Heparanase protein is capable of degrading heparan sulfate (HS) chains and enhancing activation of the coagulation system. We have previously demonstrated that estrogen enhances the expression and procoagulant activity of heparanase.

STUDY DESIGN, SIZE, DURATION
Estrogen and progestin receptor positive breast carcinoma cell lines: EMT6, T47D and MCF-7 were compared to the MDA-231 breast carcinoma cell line devoid of these receptors. This observational study incorporated 45 users of third-generation COCs progestins, 21 users of fourth-generation COCs progestins and 28 individuals not using hormonal therapy and not pregnant per history.

PARTICIPANTS/MATERIALS, SETTING, METHODS
Second-generation progestin—levonorgestrel, third-generation progestin—desogastrel (DSG), an estrogen receptor antagonist—ICI 182.780 and a progestin receptor antagonist—mifepristone, were added to cell lines. Heparanase level and procoagulant activity, HS levels, tissue factor (TF) activity and factor Xa levels were evaluated in the plasma of the study group.

MAIN RESULTS AND THE ROLE OF CHANCE
Levonorgestrel and DSG increased heparanase levels in the cells and medium. The effect of DSG was more prominent and additive to that of estrogen. The effect was inhibited by ICI 182.780. In the plasma of COC users, heparanase procoagulant activity, HS levels, TF activity and factor Xa levels were significantly higher compared to controls. In COC pills containing the same dose of estrogen, the procoagulant effect of drospirenone was significantly stronger than that of DSG and gestodene.

LIMITATIONS, REASONS FOR CAUTION
The limitations of the study include a small number of participants in each study group, although the results are statistically significant and evaluated by several different coagulation parameters.

WIDER IMPLICATIONS OF THE FINDINGS
The study demonstrates a new mechanism through which progestin affects coagulation system activation and shows that this effect is progestin type-dependent. Development of a progestin derivative with an attenuated effect on heparanase procoagulant activity may reduce thrombotic risk.

STUDY FUNDING/COMPETING INTEREST(S)
No external funding was sought for this study. Y.N. is named in a European patent application No. IL201200027 filed on 18 January 2012. Other authors have no conflict of interest to declare.

TRIAL REGISTRATION NUMBER
N/A.
Inherited Chromosomally Integrated Human Herpesvirus 6 Is a Risk Factor for Spontaneous Abortion
Authors: Miura Hiroki , Kawamura Yoshiki , Ohye Tamae , Hattori Fumihiko , Kozawa Kei , Ihira Masaru , Yatsuya Hiroshi , Nishizawa Haruki , Kurahashi Hiroki , Yoshikawa Tetsushi 
Published: September 2020

Abstract

Background
Human herpesvirus 6 (HHV-6) can be genetically transmitted from parent to child as inherited chromosomally integrated HHV-6 (iciHHV-6). HHV-6 reactivation occurs in pregnant women with iciHHV-6. We found no sex differences in the frequency of index cases with iciHHV-6 but inheritance from the father was more common. We evaluated the association between iciHHV-6 status and spontaneous abortion.

Methods
iciHHV-6 was confirmed by high viral DNA copy numbers in whole blood and somatic cells. The origin of integrated viral genome, paternal or maternal, was examined using the same method. The pregnancy history of 23 mothers in families with iciHHV-6 and 285 mothers in families without iciHHV-6 was abstracted.

Results
Of 23 iciHHV-6 index cases, 8 mothers and 15 fathers had iciHHV-6. Spontaneous abortion rates in mothers with and mothers without/fathers with iciHHV-6 and mothers in families without iciHHV-6 were 27.6%, 10.3%, and 14.8%, respectively (P = .012). Mothers with iciHHV-6 (odds ratio [OR], 6.41; 95% confidence interval [CI], 1.10–37.4) and maternal age at the most recent pregnancy ≥40 years (OR, 3.91; 95% CI, 1.30–11.8) were associated with 2 or more spontaneous abortions.

Conclusions
Mothers with iciHHV-6 is a risk factor for spontaneous abortion.
A Computational Approach to Identify Interfering Medications on Urine Drug Screening Assays without Data from Confirmatory Testing
Authors: Ayala-Lopez Nadia , Aref Layla , Colby Jennifer M , Hughey Jacob J 
Published: September 2020

Abstract
Urine drug screening (UDS) assays can rapidly and sensitively detect drugs of abuse but can also produce spurious results due to interfering substances. We previously developed an approach to identify interfering medications using electronic health record (EHR) data, but the approach was limited to UDS assays for which presumptive positives were confirmed using more specific methods. Here we adapted the approach to search for medications that cause false positives on UDS assays lacking confirmation data. From our institution’s EHR data, we used our previous dataset of 698,651 UDS and confirmation results. We also collected 211,108 UDS results for acetaminophen, ethanol and salicylates. Both datasets included individuals’ prior medication exposures. We hypothesized that the odds of a presumptive positive would increase following exposure to an interfering medication independently of exposure to the assay’s target drug(s). For a given assay–medication pair, we quantified potential interference as an odds ratio from logistic regression. We evaluated interference of selected compounds in spiking experiments. Compared to the approach requiring confirmation data, our adapted approach showed only modestly diminished ability to detect interfering medications. Applying our approach to the new data, we discovered and validated multiple compounds that can cause presumptive positives on the UDS assay for acetaminophen. Our approach can reveal interfering medications using EHR data from institutions at which UDS results are not routinely confirmed.
University Student Perspectives of Entomophagy: Positive Attitudes Lead to Observability and Education Opportunities
Authors: Petersen Matthew , Olson Olivia , Rao Sujaya 
Published: September 2020

Abstract
Positive experiences with insect food items that highlight the benefits of insect production and reduce the novelty of entomophagy are needed. Toward this goal, we developed an experiential learning lesson plan that would provide a positive experience with entomophagy and associate key educational content related to insect food items. First, two cricket powder brownie taste-test surveys were conducted with groups of university students to evaluate attitudes relating to insects as food, sustainability of insect production, and nutritional content. Students displayed a taste preference for cricket flour brownies but could not consistently differentiate between brownie types, ranked environmental and nutritional benefits associated with insect food products over taste factors alone, and indicated a positive attitude toward purchasing insect products in the future. Willingness to try other insect products in the future was significantly greater for students with increased experience with consuming insect products. These results were then used to create an university lesson plan that will allows for future evaluation of student attitudes while increasing exposure to entomophagy and providing education on the positive aspects of insects as food production. Our work highlights the favorable attitude toward insect food products shown by university students and how positive perception of entomophagy increases with continued exposure to the practice.
Movement Behavior of the Pine Needle Gall Midge (Diptera: Cecidomyiidae)
Authors: Liu Huanxiu , Duan Chunhua , Qi Yukun , Ren Lili , Wu Haiwei 
Published: September 2020

AbstractThe movement behavior of the pine needle gall midge (Thecodiplosis japonensis Uchida Et Inouye (Diptera: Cecidomyiidae)), an invasive species in China, was determined by using a tethered flight technique and digital videography in the laboratory. The flight distance, duration, and speed of females were compared at different ages (2–10 h) and ambient temperatures (17, 21, 26, and 30°C). Female flight distance and duration at 26°C were significantly greater than those at 17°C and 21°C. The age of T. japonensis did not significantly affect the three flight characteristics. For females at 2–10 h of age at 26°C and 70% RH, the maximum flight distance was 667.59 m; the longest flight time was 6,222.34 s; and the fastest flight speed was 0.44 m·s−1. For larvae wetted with water, the highest jump was 5.7 cm; the longest jump was 9.6 cm; and the greatest distance moved in 5 min was 27.13 cm, which showed that the active dispersal potential of larvae was very low.
Effects of flux variation on the surface temperatures of Earth-analog circumbinary planets
Authors: Yadavalli S Karthik , Quarles Billy , Li Gongjie , Haghighipour Nader 
Published: September 2020

ABSTRACT
The Kepler Space telescope has uncovered around thirteen circumbinary planets (CBPs) that orbit a pair of stars and experience two sources of stellar flux. We characterize the top-of-atmosphere flux and surface temperature evolution in relation to the orbital short-term dynamics between the central binary star and an Earth-analog CBP. We compare the differential evolution of an Earth-analog CBP’s flux and surface temperature with that of an equivalent single-star (ESS) system to uncover the degree by which the potential habitability of the planet could vary. For a Sun-like primary, we find that the flux variation over a single planetary orbit is greatest when the dynamical mass ratio is $\sim$0.3 for a G-K spectral binary. Using a latitudinal energy balance model, we show that the ice-albedo feedback plays a substantial role in (Earth-analog) CBP habitability due to the interplay between flux redistribution (via obliquity) and changes in the total flux (via binary gyration). We examine the differential evolution of flux and surface temperature for Earth-like analogs of the habitable zone CBPs (4 Kepler and 1 hypothetical system) and find that these analogs are typically warmer than their ESS counterparts.
The contribution of quasar absorption outflows to AGN feedback
Authors: Miller Timothy R , Arav Nahum , Xu Xinfeng , Kriss Gerard A 
Published: September 2020

ABSTRACT
Determining the distance of quasar absorption outflows from the central source (R) and their kinetic luminosity ($\dot{E}_\mathrm{\scriptstyle k}$) is crucial for understanding their contribution to active galactic nucleus (AGN) feedback. Here, we summarize the results for a sample of nine luminous quasars that were observed with the Hubble Space Telescope. We find that the outflows in more than half of the objects are powerful enough to be the main agents for AGN feedback, and that most outflows are found at R &gt; 100 pc. The sample is representative of the quasar absorption outflow population as a whole and is unbiased towards specific ranges of R and $\dot{E}_\mathrm{\scriptstyle k}$. Therefore, the analysis results can be extended to the majority of such objects, including broad absorption line quasars. We find that these results are consistent with those of another sample (seven quasars) that is also unbiased towards specific ranges of R and $\dot{E}_\mathrm{\scriptstyle k}$. Assuming that all quasars have absorption outflows, we conclude that most luminous quasars produce outflows that can contribute significantly to AGN feedback. We also discuss the criterion for whether an outflow is energetic enough to cause AGN feedback effects.
Fundamental parameters for 45 open clusters with Gaia DR2, an improved extinction correction and a metallicity gradient prior
Authors: Monteiro H , Dias W S , Moitinho A , Cantat-Gaudin T , Lépine J R D , Carraro G , Paunzen E 
Published: September 2020

ABSTRACT
Reliable fundamental parameters of open clusters (OCs) such as distance, age, and extinction are key to our understanding of Galactic structure and stellar evolution. In this work, we use Gaia Data Release 2 (DR2) to investigate 45 OCs listed in the New catalogue of optically visible open clusters and candidates (DAML) but with no previous astrometric membership estimation based on Gaia DR2. In the process of selecting targets for this study, we found that some clusters reported as new discoveries in recent papers based on Gaia DR2 were already known clusters listed in DAML. Cluster memberships were determined using a maximum likelihood method applied to Gaia DR2 astrometry. This has allowed us to estimate mean proper motions and mean parallaxes for all investigated clusters. Mean radial velocities were also determined for 12 clusters, 7 of which had no previous published values. We have improved our isochrone fitting code to account for interstellar extinction using an updated extinction polynomial for the Gaia DR2 photometric bandpasses and the Galactic abundance gradient as a prior for metallicity. The updated procedure was validated with a sample of clusters with high-quality [Fe/H] determinations. We then did a critical review of the literature and verified that our cluster parameter determinations represent a substantial improvement over previous values.
A fresh look at the RR Lyrae population in the Draco dwarf spheroidal galaxy with Gaia
Authors: Muraveva Tatiana , Clementini Gisella , Garofalo Alessia , Cusano Felice 
Published: September 2020

ABSTRACT
We present a catalogue of 285 RR Lyrae stars (RRLs) in the Draco dwarf spheroidal (dSph) galaxy, obtained by combining data from a number of different surveys including the Data Release 2 (DR2) of the European Space Agency cornerstone mission Gaia. We have determined individual distances to the RRLs in our sample using for the first time a Gaia G-band luminosity–metallicity relation ($M_{G}\small{--}{\rm [Fe/H]}$) and study the structure of the Draco dSph as traced by its RRL population. We find that the RRLs located in the western/south-western region of Draco appear to be closer to us, which may be a clue of interaction between Draco and the Milky Way. The average distance modulus of Draco measured with the RRLs is $\mu =19.53\pm 0.07$ mag, corresponding to a distance of $80.5\pm 2.6$ kpc, in good agreement with previous determinations in the literature. Based on the pulsation properties of the RRLs, we confirm the Oosterhoff-intermediate nature of Draco. We present an additional sample of 41 candidate RRLs in Draco, which we selected from the Gaia DR2 catalogue based on the uncertainty of their G-band magnitudes. Additional epoch data that will become available in the Gaia Data Release 3 will help to confirm whether these candidates are bona fide Draco RRLs.