bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Unexplored Data Sources on the Historical Distribution of Three Vector Tick Species in Illinois
Authors: Gilliam Beth , Gronemeyer Peg , Chakraborty Sulagna , Winata Fikriyah , Lyons Lee Ann , Miller-Hunt Catherine , Tuten Holly C , Debosik Samantha , Freeman Debbie , O’hara-Ruiz Marilyn , Mateus-Pinilla Nohra 
Published: December 2019

AbstractWe updated the Illinois historical (1905–December 2017) distribution and status (not reported, reported or established) maps for Amblyomma americanum (L.) (Acari: Ixodidae), Dermacentor variabilis (Say) (Acari: Ixodidae), and Ixodes scapularis (Say) (Acari: Ixodidae) by compiling publicly available, previously unexplored or newly identified published and unpublished data (untapped data). Primary data sources offered specific tick-level information, followed by secondary and tertiary data sources. For A. americanum, D. variabilis, and I. scapularis, primary data contributed to 90% (4,045/4,482), 80% (2,124/2,640), and 32% (3,490/10,898) tick records vs 10%, 20%, and 68%, respectively from secondary data; primary data updated status in 95% (62/65), 94% (51/54) and in 90% (9/10) of the updated counties for each of these tick species; by 1985 there were tick records in 6%, 68%, and 0% of the counties, compared to 20%, 72%, and 58% by 2004, and 77%, 96%, and 75% of the counties by 2017, respectively for A. americanum, D. variabilis, and I. scapularis. We document the loss of tick records due to unidentified, not cataloged tick collections, unidentified ticks in tick collections, unpublished data or manuscripts without specific county location, and tick-level information, to determine distribution and status. In light of the increase in tick-borne illnesses, updates in historical distributions and status maps help researchers and health officials to identify risk areas for a tick encounter and suggest targeted areas for public outreach and surveillance efforts for ticks and tick-borne diseases. There is a need for a systematic, national vector surveillance program to support research and public health responses to tick expansions and tick-borne diseases.
Spectroscopic and photometric studies of four W UMa-type eclipsing binaries – II
Authors: Zhang Liyun , Zhu ZhongZhong , Yue Qiang , Terheide Rachel , Han Xianming L , Long Liu , Lu Hongpeng , Pi Qingfeng , Jiang Linyiang 
Published: December 2019

ABSTRACT
We performed photometric and spectroscopic studies on four W Ursae Majoris eclipsing binaries (V384 Ser, AQ Psc, V480 Gem and 2MASS J07095549+3643564). The binaries were observed from 2015 to 2018. The orbital period of V384 Ser showed an interesting cyclic variation overlaying a decreasing period, which may be caused by the light-time effect (LITE) of approximately 2.84 ± 0.01 yr or the magnetic activity cycle of 2.83 ± 0.01 yr. For AQ Psc, we found cyclic variations in its period caused by the LITE either as a result of a tertiary companion or because of a magnetic activity cycle. We derived the cycle of the tertiary component of AQ Psc as 23.87 (±0.14) yr or a magnetic cycle of 44.08 (±1.15) yr. We revised the linear ephemeris of eclipsing binaries V480 Gem and 2MASS J07095549+3643564. We also determined their orbital parameters and star-spot parameters by fitting the light curves. In addition, we found weak excess emissions in the LAMOST spectra of V384 Ser, AQ Psc, V480 Gem and 2MASS J07095549+3643564 in the Hα line, which indicates weak chromospheric activities.
The peculiar kinematics of the multiple populations in the globular cluster Messier 80 (NGC 6093)
Authors: Kamann S , Dalessandro E , Bastian N , Brinchmann J , den Brok M , Dreizler S , Giesers B , Göttgens F , Husser T-O , Krajnović D , van de Ven G , Watkins L L , Wisotzki L 
Published: December 2019

ABSTRACT
We combine MUSE spectroscopy and Hubble Space Telescope ultraviolet (UV) photometry to perform a study of the chemistry and dynamics of the Galactic globular cluster Messier 80 (M80, NGC 6093). Previous studies have revealed three stellar populations that vary not only in their light-element abundances, but also in their radial distributions, with the concentration decreasing with increasing nitrogen enrichment. This remarkable trend, which sets M80 apart from other Galactic globular clusters, points towards a complex formation and evolutionary history. To better understand how M80 formed and evolved, revealing its internal kinematics is key. We find that the most N-enriched population rotates faster than the other two populations at a 2σ confidence level. While our data further suggest that the intermediate population shows the least amount of rotation, this trend is rather marginal (1−2σ). Using axisymmetric Jeans models, we show that these findings can be explained from the radial distributions of the populations if they possess different angular momenta. Our findings suggest that the populations formed with primordial kinematical differences.
I–Love–Q relations for realistic white dwarfs
Authors: Taylor Andrew J , Yagi Kent , Arras Phil L 
Published: December 2019

ABSTRACT
The space-borne gravitational wave interferometer, Laser Interferometer Space Antenna, is expected to detect signals from numerous binary white dwarfs. At small orbital separation, rapid rotation and large tidal bulges may allow for the stellar internal structure to be probed through such observations. Finite-size effects are encoded in quantities like the moment of inertia (I), tidal Love number (Love), and quadrupole moment (Q). The universal relations among them (I–Love–Q relations) can be used to reduce the number of parameters in the gravitational-wave templates. We here study I–Love–Q relations for more realistic white dwarf models than used in previous studies. In particular, we extend previous works by including (i) differential rotation and (ii) internal temperature profiles taken from detailed stellar evolution calculations. We use the publicly available stellar evolution code mesa to generate cooling models of both low- and high-mass white dwarfs. We show that differential rotation causes the I–Q relation (and similarly the Love–Q relation) to deviate from that of constant rotation. We also find that the introduction of finite temperatures causes the white dwarf to move along the zero-temperature mass sequence of I–Q values, moving towards values that suggest a lower mass. We further find that after only a few Myr, high-mass white dwarfs are well described by the zero-temperature model, suggesting that the relations with zero temperature may be good enough in most practical cases. Low-mass, He-core white dwarfs with thick hydrogen envelopes may undergo long periods of H burning which sustain the stellar temperature and allow deviations from the I–Love–Q relations for longer times.
Probing black hole accretion tracks, scaling relations, and radiative efficiencies from stacked X-ray active galactic nuclei
Authors: Shankar Francesco , Weinberg David H , Marsden Christopher , Grylls Philip J , Bernardi Mariangela , Yang Guang , Moster Benjamin , Fu Hao , Carraro Rosamaria , Alexander David M , Allevato Viola , Ananna Tonima T , Bongiorno Angela , Calderone Giorgio , Civano Francesca , Daddi Emanuele , Delvecchio Ivan , Duras Federica , La Franca Fabio , Lapi Andrea , Lu Youjun , Menci Nicola , Mezcua Mar , Ricci Federica , Rodighiero Giulia , Sheth Ravi K , Suh Hyewon , Villforth Carolin , Zanisi Lorenzo 
Published: December 2019

ABSTRACT
The masses of supermassive black holes at the centres of local galaxies appear to be tightly correlated with the mass and velocity dispersions of their galactic hosts. However, the local Mbh–Mstar relation inferred from dynamically measured inactive black holes is up to an order-of-magnitude higher than some estimates from active black holes, and recent work suggests that this discrepancy arises from selection bias on the sample of dynamical black hole mass measurements. In this work, we combine X-ray measurements of the mean black hole accretion luminosity as a function of stellar mass and redshift with empirical models of galaxy stellar mass growth, integrating over time to predict the evolving Mbh–Mstar relation. The implied relation is nearly independent of redshift, indicating that stellar and black hole masses grow, on average, at similar rates. Matching the de-biased local Mbh–Mstar relation requires a mean radiative efficiency ε ≳ 0.15, in line with theoretical expectations for accretion on to spinning black holes. However, matching the ‘raw’ observed relation for inactive black holes requires ε ∼ 0.02, far below theoretical expectations. This result provides independent evidence for selection bias in dynamically estimated black hole masses, a conclusion that is robust to uncertainties in bolometric corrections, obscured active black hole fractions, and kinetic accretion efficiency. For our fiducial assumptions, they favour moderate-to-rapid spins of typical supermassive black holes, to achieve ε ∼ 0.12–0.20. Our approach has similarities to the classic Soltan analysis, but by using galaxy-based data instead of integrated quantities we are able to focus on regimes where observational uncertainties are minimized.
Artificial Neural Networks to Assess Virtual Reality Anterior Cervical Discectomy Performance
Authors: Mirchi Nykan , Bissonnette Vincent , Ledwos Nicole , Winkler-Schwartz Alexander , Yilmaz Recai , Karlik Bekir , Del Maestro Rolando F 
Published: December 2019

Abstract

BACKGROUND
Virtual reality surgical simulators provide a safe environment for trainees to practice specific surgical scenarios and allow for self-guided learning. Artificial intelligence technology, including artificial neural networks, offers the potential to manipulate large datasets from simulators to gain insight into the importance of specific performance metrics during simulated operative tasks.

OBJECTIVE
To distinguish performance in a virtual reality-simulated anterior cervical discectomy scenario, uncover novel performance metrics, and gain insight into the relative importance of each metric using artificial neural networks.

METHODS
Twenty-one participants performed a simulated anterior cervical discectomy on the novel virtual reality Sim-Ortho simulator. Participants were divided into 3 groups, including 9 post-resident, 5 senior, and 7 junior participants. This study focused on the discectomy portion of the task. Data were recorded and manipulated to calculate metrics of performance for each participant. Neural networks were trained and tested and the relative importance of each metric was calculated.

RESULTS
A total of 369 metrics spanning 4 categories (safety, efficiency, motion, and cognition) were generated. An artificial neural network was trained on 16 selected metrics and tested, achieving a training accuracy of 100% and a testing accuracy of 83.3%. Network analysis identified safety metrics, including the number of contacts on spinal dura, as highly important.

CONCLUSION
Artificial neural networks classified 3 groups of participants based on expertise allowing insight into the relative importance of specific metrics of performance. This novel methodology aids in the understanding of which components of surgical performance predominantly contribute to expertise.
Gender Politics and Legislative Networks in Taiwan: An Analysis of Women-Bill Co-Sponsorship and Bill Success
Authors: Shim Jaemin 
Published: December 2019

Abstract
This article examines how legislative networks can be utilised to further the interests of female voters. Specifically, I investigate how legislators’ gender and partisanship within co-sponsorship networks are related to the successful passage of women bills. For this goal, the article focusses on Taiwan—where both women’s descriptive and substantive representations have improved dramatically since democratisation and, at the same time, co-sponsoring bills have been a legislative process of the ongoing significance. The article utilises an original bill co-sponsorship dataset that consists of 232,734 co-sponsors related to all bills submitted between 2005 and 2016. By comparing women and non-women bills, the article demonstrates that the legislative effectiveness on women bills varied by legislator’s gender and affiliated party. That is, the proportion of male legislators in the co-sponsorship network did not effect on women bill success, while it turned out to be positively related to non-women bill success. Moreover, the proportion of right-leaning party legislators in the co-sponsorship network decreased the odds of women bill passage while increasing the chance of non-women bill ones. Despite the increasing participation of male legislators and right-leaning party legislators in co-sponsoring women’s issues in Taiwan, the results demonstrate that their role was limited on the success of women bills.
Weak scale from Planck scale: Mass scale generation in a classically conformal two-scalar system
Authors: Haruna Junichi , Kawai Hikaru 
Published: December 2019

Abstract
In the standard model, the weak scale is the only parameter with mass dimensions. This means that the standard model itself cannot explain the origin of the weak scale. On the other hand, from the results of recent accelerator experiments, except for some small corrections, the standard model has increased the possibility of being an effective theory up to the Planck scale. From these facts, it is naturally inferred that the weak scale is determined by some dynamics from the Planck scale. In order to answer this question, we rely on the multiple point criticality principle as a clue and consider the classically conformal $\mathbb{Z}_2\times \mathbb{Z}_2$ invariant two-scalar model as a minimal model in which the weak scale is generated dynamically from the Planck scale. This model contains only two real scalar fields and does not contain any fermions or gauge fields. In this model, due to a Coleman–Weinberg-like mechanism, the one-scalar field spontaneously breaks the $ \mathbb{Z}_2$ symmetry with a vacuum expectation value connected with the cutoff momentum. We investigate this using the one-loop effective potential, renormalization group and large-$N$ limit. We also investigate whether it is possible to reproduce the mass term and vacuum expectation value of the Higgs field by coupling this model with the standard model in the Higgs portal framework. In this case, the one-scalar field that does not break $\mathbb{Z}_2$ can be a candidate for dark matter and have a mass of about several TeV in appropriate parameters. On the other hand, the other scalar field breaks $\mathbb{Z}_2$ and has a mass of several tens of GeV. These results will be verifiable in near-future experiments.
Eugen Bleuler’s Views on the Genetics of Schizophrenia in 1917
Authors: Kendler Kenneth S 
Published: December 2019

Abstract
In 1917, Eugen Bleuler published an article (Mendelismus bei Psychosen, speziell bei der Schizophrenie [Mendelism in the Psychoses, especially Schizophrenia]) in response to the recently published first systematic family study of dementia praecox (DP) by Ernst Rüdin, then working under Kraepelin in Munich. Although briefly commented upon by David Rosenthal in 1978, this article has never been thoroughly reviewed or translated. Of the many themes addressed, four are especially noteworthy. First, Bleuler argues that understanding the transmission patterns of schizophrenia in families requires definitive knowledge about the boundaries of the phenotype which he argues are unknown. Rüdin’s choice—Kraepelin’s concept of DP—is, he asserts, too narrow. Clarifying the genetics of schizophrenia is inextricably bound up with the problem of defining the phenotype. Second, Bleuler argues for the importance of “erbschizose” (literally “inherited schizoidia”) wondering whether his “4 As” or other “brain-anatomical, chemical, [or] neurological characteristics” might underlie the genetic transmission of schizophrenia. Third, Bleuler was deeply interested in the nature of the onset of schizophrenia, suggesting that environmental adversity could provoke “latent illness to become manifest.” It was important, he argued, to identify such risk factors and incorporate them into genetic models. Fourth, although not optimistic that current knowledge would permit a resolution of the transmission model for schizophrenia, he finds single-locus models implausible and at several points wonders whether polygenic models might better apply. A complete translation of the article is provided.
GABA and glycine neurons from the ventral medullary region inhibit hypoglossal motoneurons
Authors: Dergacheva Olga , Fleury-Curado Thomaz , Polotsky Vsevolod Y , Kay Matthew , Jain Vivek , Mendelowitz David 
Published: December 2019

Abstract
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive sleep-related losses of upper airway patency that occur most frequently during rapid eye movement (REM) sleep. Hypoglossal motoneurons play a key role in regulating upper airway muscle tone and patency during sleep. REM sleep activates GABA and glycine neurons in the ventral medulla (VM) to induce cortical desynchronization and skeletal muscle atonia during REM sleep; however, the role of this brain region in modulating hypoglossal motor activity is unknown. We combined optogenetic and chemogenetic approaches with in-vitro and in-vivo electrophysiology, respectfully, in GAD2-Cre mice of both sexes to test the hypothesis that VM GABA/glycine neurons control the activity of hypoglossal motoneurons and tongue muscles. Here, we show that there is a pathway originating from GABA/glycine neurons in the VM that monosynaptically inhibits brainstem hypoglossal motoneurons innervating both tongue protruder genioglossus (GMNs) and retractor (RMNs) muscles. Optogenetic activation of ChR2-expressing fibers induced a greater postsynaptic inhibition in RMNs than in GMNs. In-vivo chemogenetic activation of VM GABA/glycine neurons produced an inhibitory effect on tongue electromyographic (EMG) activity, decreasing both the amplitude and duration of inspiratory-related EMG bursts without any change in respiratory rate. These results indicate that activation of GABA/glycine neurons from the VM inhibits tongue muscles via a direct pathway to both GMNs and RMNs. This inhibition may play a role in REM sleep associated upper airway obstructions that occur in patients with OSA.
Assessing Deprivation with an Ordinal Variable: Theory and Application to Sanitation Deprivation in Bangladesh
Authors: Seth Suman , Yalonetzky Gaston 
Published: December 2019

AbstractThe challenges associated with poverty measurement using a cardinal variable have received much attention over the past four decades, but there is a dearth of literature on how to meaningfully assess poverty with an ordinal variable. This article proposes a class of simple, intuitive, and policy-relevant poverty measures for ordinal variables. The measures are sensitive to the depth of deprivations, unlike the headcount ratio. Moreover, under appropriate restrictions, the measures ensure that priority is given to the poorest among the poor when targeting, monitoring, and evaluating poverty alleviation programs. To assess the robustness of poverty comparisons to alternative choices of parameters, the article develops various stochastic dominance tests (some of which are novel contributions to the stochastic dominance literature). The empirical illustration documenting changes in sanitation deprivation in Bangladesh showcases the measures’ ability to identify instances in which overall sanitation deprivation improved while leaving the poorest behind.
Diagnostic approach to occupational rhinitis: the role of nasal provocation tests
Authors: Ronsmans Steven , Steelant Brecht , Backaert Wout , Nemery Benoit , Van Gerven Laura 
Published: December 2019

Purpose of review
The diagnosis of occupational rhinitis is a challenge. Underdiagnosis is substantial as the clinical presentation is nonspecific and often no occupational history is taken. Detection of occupational rhinitis can be improved by including screening questions on occupational exposure in the assessment of every patient with adult-onset rhinitis.

Recent findings
Case reports, case series and epidemiological studies continuously demonstrate new sensitizers and irritants capable of inducing allergic or nonallergic (irritant-induced) occupational rhinitis. Recent reviews have focused on the value of immunological tests with specific IgE, skin prick tests or basophil activation tests in demonstrating sensitization to occupational agents. Nasal provocation tests (NPT) can establish a definite diagnosis of allergic occupational rhinitis. Several NPT guidelines have been published, however, focusing exclusively on standardized high-molecular weight allergens. When performing NPT with nonstandardized agents -- like most occupational sensitizers -- adapted protocols are needed.

Summary
We provide pragmatic guidance to clinicians taking care of rhinitis patients on how to diagnose occupational rhinitis, based on recent insights from the literature. We focus on the challenges in the diagnostic work-up, on how to identify suspected causes, and on the role of NPT.
Mechanisms of resistance and predictive biomarkers of response to targeted therapies and immunotherapies in metastatic melanoma
Authors: Mourah Samia , Louveau Baptiste , Dumaz Nicolas 
Published: December 2019

Purpose of review
Thanks to mitogen-activated protein kinase inhibitors (MAPKi) and immune checkpoint inhibitors (ICI), major progress has been made in the field of melanoma treatment. However, long-term success is still scarce because of the development of resistance. Understanding these mechanisms of resistance and identifying predictive genomic biomarkers are now key points in the therapeutic management of melanoma patients.

Recent findings
Multiple and complex mechanisms of resistance to MAPKi or ICI have been uncovered in the past few years. The lack of response can be driven by mutations and nonmutational events in tumor cells, as well as by changes in the tumor microenvironment. Melanoma cells are also capable of rapidly switching their molecular and cellular phenotype, leading to an initial drug-tolerant favorizing melanoma resistance. Tumor molecular profiling and circulating tumor cell analyses are of high interest as predictive biomarkers as well as studying immunogenic changes and microbiome in ICI-treated patients.

Summary
Resistance to MAPKi and ICI is a key point in therapeutic management of metastatic melanoma patients. Validated biomarkers predicting response to therapy are urgently needed to move toward personalized medicine. Combinatory treatments guided by the understanding of resistance mechanisms will be of major importance in the future of melanoma therapy.