bluuebunny/crossref_metadata_2025_split huggingface dataset:
Un poids-étalon de Mactaris au nom de Q. Ivnivs Rvsticvs, praefectvs Vrbi
Authors: Hamrouni Mohamed Riadh , Naddari Lotfi 
Published: April 2020

Cette étude porte sur un poids épigraphe
découvert dans le site archéologique de Mactar (l’antique Mactaris, en
Tunisie). C’est un sphéroïde aplati qui affiche une légende au nom du
préfet de la Ville du règne conjoint de Marc Aurèle et de Lucius
Verus : Q. Iunius Rusticus. Il vient enrichir le dossier le plus
important de jeu de pondera mentionnant des autorités centrales de
l’Empire découverts dans plusieurs endroits de l’Occident romain.
Émanant d’une autorité officielle, ces pondera sont destinés à une
large diffusion pour la vérification de l’authenticité des poids mis
en circulation. Cette recherche se termine par un essai
d’identification de la salle officielle des poids et des mesures à
laquelle se rattache le poids en question : un édicule situé dans le
forum de Trajan, selon une hypothèse proposée par G.-Ch. Picard, ou
une pièce particulière du programme architectural du macellum
adjacent.
Cyclophilin D Regulates Antiviral CD8+ T Cell Survival in a Cell-Extrinsic Manner
Authors: Condotta Stephanie A , Downey Jeffrey , Pardy Ryan D , Valbon Stefanie F , Tarrab Esther , Lamarre Alain , Divangahi Maziar , Richer Martin J 
Published: April 2020

Abstract
CD8+ T cell–mediated immunity is critical for host defense against viruses and requires mitochondria-mediated type I IFN (IFN-I) signaling for optimal protection. Cyclophilin D (CypD) is a mitochondrial matrix protein that modulates the mitochondrial permeability transition pore, but its role in IFN-I signaling and CD8+ T cell responses to viral infection has not been previously explored. In this study, we demonstrate that CypD plays a critical extrinsic role in the survival of Ag-specific CD8+ T cell following acute viral infection with lymphocytic choriomeningitis virus in mice. CypD deficiency resulted in reduced IFN-I and increased CD8+ T cell death, resulting in a reduced antiviral CD8+ T cell response. In addition, CypD deficiency was associated with an increase in pathogen burden at an early time-point following infection. Furthermore, our data demonstrate that transfer of wild-type macrophages (expressing CypD) to CypD-deficient mice can partially restore CD8+ T cell responses. These results establish that CypD plays an extrinsic role in regulating optimal effector CD8+ T cell responses to viral infection. Furthermore, this suggests that, under certain circumstances, inhibition of CypD function may have a detrimental impact on the host’s ability to respond to viral infection.
Hospital care in Departments defined as COVID-free: A proposal for a safe hospitalization protecting healthcare professionals and patients not affected by COVID-19
Authors: Leonardi Rosario , Bellinzoni Piera , Broglia Luigi , Colombo Renzo , De Marchi Davide , Falcone Lorenzo , Giusti Guido , Grasso Vincenzo , Mantica Guglielmo , Passaretti Giovanni , Proietti Silvia , Russo Antonio , Saitta Giuseppe , Smelzo Salvatore , Suardi Nazareno , Gaboardi Franco 
Published: April 2020

The COVID-19 pandemic influenced the normal course of clinical practice leading to significant delays in the delivery of healthcare services for patients non affected by COVID-19. In the near future, it will be crucial to identify facilities capable of providing health care in compliance with the safety of healthcare professionals, administrative staff and patients. All the staff involved in the project of a Covid-free hospital should be subjected to a diagnostic swab for COVID-19 before the beginning of healthcare activity and then periodically in order to avoid the risk of contamination of patients during the process of care. The modifications of various activities involved in the process of care are described: outpatient care, reception of inpatients, inpatient ward and operating room. For outpatient care, modality of appointment procedure, characteristics of waiting room and personal protective equipment (PPE) for healthcare professionals and administrative staff are presented. Reception of inpatients shall be conditional on a negative swab for COVID-19 obtained with a drive-in procedure. The management of the operating room represents the most crucial step of the patient's care process. The surgical team should be restricted and monitored with periodic swabs; surgical procedures should be performed by experienced surgeons according to standard procedures; surgical training experimental treatments and research protocols should be suspended. Adequate personal protective equipment and measures to reduce aerosolization in the operating room (closed circuits, continuous cycle insufflators, fume extraction) should be adopted. Prevention of possible transmission of the virus during procedures in open, laparoscopic and endoscopic surgery is to use a multi-tactic approach, which includes correct filtration and ventilation of the operating room, the use of appropriate PPE (FFP3 plus surgical mask and protective visor for all the staff working in the operating room) and smoke evacuation devices with a suction and filter system.

on behalf of the UrOP Executive CommitteeGiuseppe Ludovico, Angelo Cafarelli, Ottavio De Cobelli, Ferdinando De Marco, Giovanni Ferrari, Stefano Pecoraro, Angelo Porreca, Domenico Tuzzolo
A Note on the Vanishing Viscosity Limit in the Yudovich Class
Authors: Seis Christian 
Published: April 2020

AbstractWe consider the inviscid limit for the two-dimensional Navier–Stokes equations in the class of integrable and bounded vorticity fields. It is expected that the difference between the Navier–Stokes and Euler velocity fields vanishes in $L^2$ with an order proportional to the square root of the viscosity constant $\nu $. Here, we provide an order $ (\nu /|\log \nu | )^{\frac 12\exp (-Ct)}$ bound, which slightly improves upon earlier results by Chemin.
Modelling the mineralogical composition and solubility of mineral dust in the Mediterranean area with CHIMERE 2017r4
Authors: Menut Laurent , Siour Guillaume , Bessagnet Bertrand , Couvidat Florian , Journet Emilie , Balkanski Yves , Desboeufs Karine 
Published: April 2020

Abstract. Modelling of mineral dust is often done using one single mean species. But for biogeochemical studies, it could be useful to access to a more
detailed information on differentiated mineral species and the associated chemical composition. Differentiating between mineral species would also
induce different optical properties and densities and then different radiative impact, transport and deposition. In this study, the mineralogical
differentiation is implemented in the CHIMERE regional chemistry-transport model, by using global databases. The results show that this
implementation does not change the results much in terms of aerosol optical depth, surface concentrations and deposition fluxes. But the information
on mineralogy, with a high spatial (a few kilometres) and temporal (1 h) resolution, is now available and is ready to be used for future
biogeochemical studies.
Risk assessment of sea ice disasters on fixed jacket platforms in Liaodong Bay
Authors: Xu Ning , Yuan Shuai , Liu Xueqin , Ma Yuxian , Shi Wenqi , Zhang Dayong 
Published: April 2020

Abstract. Sea ice disasters seriously threaten the structural safety of oil
platforms in the Bohai Sea. Therefore, it is necessary to carry out
a risk assessment of sea ice disasters on oil platforms in the
Bohai Sea. In this study, a risk assessment of sea ice disasters on
fixed jacket platforms in Liaodong Bay, in the Bohai Sea, was performed
in five steps. Firstly, the formation mechanisms of sea ice
disasters were analyzed and the sources and modes of sea ice risks
were summarized. Secondly, according to the calculation formulas of
extreme ice force, dynamic ice force, and accumulated force, several
ice indices such as thickness, motion, strength, period, and
concentration were proposed as the hazard indices, and corresponding
values were then assigned to the proposed indices based on ice
conditions in the Bohai Sea. Thirdly, based on four structural
failure modes – structural overturning by extreme ice force (Mode 1),
structural fracture failure caused by dynamic ice force (Mode 2),
the damage of facilities caused by dynamic ice force (Mode 3), and
structural function failure caused by accumulated ice (Mode 4) – the
structural vulnerability index, overturning index, dynamic index,
ice-induced vibration index, and function index were proposed, and
corresponding values were assigned to the structural vulnerability
index of fixed jacket platforms in Liaodong Bay. Fourthly, the
weight of each risk index was determined according to previously
recorded sea ice disasters and accidents, and the sea ice risk was
then calculated with the weighted synthetic index method. Finally,
with the above index system and risk assessment methods, the risk
assessment of sea ice disasters on 10 jacket platforms in three sea
areas in Liaodong Bay was carried out. The analysis results
showed that efficient sea ice prevention strategies could largely
mitigate the sea ice-induced vibration-related risks of jacket
platforms in Liaodong Bay. If steady-state vibration occurs
(usually in front of the vertical legged structure) or the
structural fundamental frequency is high, the structural
vulnerability is significantly increased and the calculated risk
levels are high. The sea ice risk assessment method can be applied
in the design, operation, and management of other engineering
structures in sea ice areas.
Responsabilidad penal en el ámbito bancario: la delimitación entre los delitos de apropiación indebida y administración desleal en el caso de las tarjetas black
Authors: Correcher Mira Jorge 
Published: April 2020

Una de las consecuencias más importantes de la crisis económico- financiera ha sido situar en el debate político-criminal determinadas cuestiones asociadas a la mala praxis en el ámbito bancario. Sobre esta cuestión, uno de los supuestos de mayor importancia ha sido el llamado caso de las Tarjetas Black, relativo al cobro de remuneraciones fuera de lo previsto legalmente por los directivos de Caja Madrid y Bankia. En este trabajo se presenta un análisis de la problemática estudiada, en relación con los criterios seguidos por la SAN 4/2017, de 23 de febrero y la STS 438/2018, de 3 de octubre, para la resolución del caso. One of the most important consequences of the economic and financial crisis has been bringing up to the criminal policy debate some issues regarding bad practices in the banking sector. About it, one of the leading cases has been the so-called Black Cards case, concerning the charging of unlawful executive compensations by Caja Madrid and Bankia executives. In this work, an analysis of this issue has been presented, according to the criteria followed by the SAN 4/2017 and the STS 438/2018, in order to resolve this case
Interlocuções entre os discursos médico e psicanalítico: por uma leitura sobre a desmedicalização
Authors: De Azevedo Luciana Jaramillo Caruso 
Published: April 2020

A tensão existente entre a medicina e a psicanálise mobiliza profícuas discussões. A psicanálise se destaca por ser uma área do conhecimento que oferece dispositivos significativos para fazer frente à medicalização desenfreada, possibilitando a escuta de novas formas de subjetividade na cena contemporânea. O presente estudo propõe uma reflexão acerca dos discursos médico e psicanalítico no que se refere ao processo de medicalização. As noções de sintoma, diagnóstico e sofrimento se configuram como dispositivos balizadores desta discussão. O sintoma psicanalítico enquanto portador de sentido e significação carrega consigo a verdade do sujeito. Diferentemente da medicina onde se tenta abolir o sintoma, a psicanálise compreende o sintoma como um significante que aponta para a estrutura de linguagem inconsciente. Em função disso, faz-se necessário um constante aprofundamento da dialética entre os saberes médico e psicanalítico com o intuito de se construir uma ética do cuidado que ultrapasse a perspectiva biologizante/medicalizante.
The association between a free medicine program and functioning in people with schizophrenia: a cross-sectional study in Liuyang, China
Authors: Gong Wenjie , Zhang Chao , Xu Dong (Roman) , Xiao Shuiyuan , Yu Yu , Caine Eric D. 
Published: April 2020

Background
Persons with schizophrenia frequently discontinue or avoid medications. Under a national community-based mental health program many places in China have started to provide free medications to people with severe mental health disorders in their communities. In the free medication program (FMP) in Liuyang, China, peripatetic psychiatrists prescribed and dispensed antipsychotic medications free of charge at regular intervals and places convenient for all patients through the primary health care system since 2006. Our study aims to test whether adherence to this FMP improves the functioning of people with schizophrenia.

Methods
The research was conducted in Liuyang, a rural county in central China. Data were obtained from three sources: an ad-hoc survey and the program’s management system in 2013 and in-home interviews in 2014 in Liuyang. We conducted a cross-sectional propensity-score based analysis of the “dose” effect of FMP participation on their level of functioning, using medication refill adherence as a proxy for the participatory intensity in the program.

Results
Only 50.9% of 2,332 participants came for all refills in 2012. Higher refill adherence was associated with slightly worse functional outcomes. The main reasons for refill non-adherence were “unwilling to take medication or only took medication when unwell” (23.6%), “forgot or missed the appointment” (20.6%) and “hospitalized” (20.1%).

Conclusions
The FMP program in Liuyang seemed to have successfully removed barriers in cost and access. However, better refill adherence was not associated with better functional outcomes in this study, which might have been the result of reverse causation. To improve the effectiveness of the FMP, patient-centered measures should be considered.
The World Health Organization's recent work on the lexicography of mental disorders
Authors: Janca A , Sartorius N 
Published: July 2002

SummaryStandardization of nomenclature and terminology used in the field of mental health has been one of the main goals of the World Health Organization's (WHO) Mental Health Programme among recent activities undertaken to achieve this goal, is the development of definition and guidelines accompanying the chapter dealing with mental disorders in the tenth revision of the International Classification of Diseases (ICD-10) and of a set of instruments for the assessment of mental disorders. To enhance common understanding and uniformity of usage of the terms embedded in the classification and instruments and to facilitate their use in different cultures and settings, a series of lexica and glossaries has also been produced by WHO. The article describes the basic characteristics of the Lexicon of psychiatric and mental health terms, 2nd edition; Lexicon of alcohol and drug terms; Lexicon of crosscultural terms in mental health; SCAN glossary; and the ICD-10 symptom glossary for mental disorders.
Symptoms and signs in single and mixed genital infections
Authors: Mårdh P.‐A , Tchoudomirova K , Elshibly S , Hellberg D 
Published: July 2002

AbstractObjective: To compare symptoms and signs in women with single and mixed genital infections. Methods: The study population comprised 996 apparently healthy women. Gynecological symptoms and signs were looked for and diagnostics for the most prevalent gynecological infections were made. Results: When co‐infections were excluded, chlamydial infections, bacterial vaginosis and cervical human papillomavirus infections were associated with a fishy malodor; for the two former conditions an easily bleeding ectopy was also found. Vaginal candidosis showed characteristic symptoms and signs. Genital warts were associated with dysuria, general and lower abdominal pain. Out of 494 women with a genital infection, 112 (22.7%) had a mixed infection, which in some cases influenced symptoms and signs. Conclusion: Many women who consider themselves gynecologically healthy, may nevertheless harbor one or more infectious agents. The need to exclude multiple infections is obvious. Positive predictive values were for specific symptoms and signs were generally low.
Gaba‐stimulated chloride uptake during avian CNS development: modulation by neurosteroids
Authors: Gravielle Maria Clara , De Novara Alba Mitridate , De Plazas Sara Fiszer 
Published: July 2002

AbstractIn the present report we studied the GABA‐stimulated 36Cl− uptake during chick optic lobe development in order to establish the ontogenetic profile of the functional GABAA receptor complex. A concentration‐dependent stimulation of 36Cl− influx by GABA was demonstrated, starting at developmental stages as early as 10 days of incubation. The maximal GABA‐induced 36Cl− uptake changed significantly during ontogeny with highest values near hatching. However, GABA potency to stimulate ion influx remained unchanged. We also examined the effect of two neurosteroids, allopregnanolone and epipregnanolone, on GABA‐stimulated 36Cl− influx at three developmental stages (embryonic day 14, post‐hatching day 1 and adult stage). Both steroids enhanced ion uptake in a concentration‐dependent manner, exerting greater stimulatory effects at early developmental stages. Allopregnanolone displayed EC50 values lower than epipregnanolone at all three time points and was also more potent at post‐hatching stages. Analysis of the GABA concentration‐effect curve disclosed that both steroid decreased EC50 values for GABA stimulation while Emax levels were unaffected. In conclusion, our results showed an early appearance of the GABA‐associated chloride channel together with the ability of neurosteroids to modulate GABA‐gating of such channel.
Legal protection in psychiatry. The jurisprudence of the organs of the European convention of human rights
Authors: Dougin AM 
Published: July 2002

SummaryThe European Convention of Human Rights recognises a certain number of rights and freedoms for persons within States' jurisdiction. For those confined in psychiatric hospitals, this legal protection concerns first of all the lawfulness of deprivation of liberty, which must conform to the conditions laid down by the Convention as interpreted by the case-law of the Convention organs (the Commission and Court of Human Rights). The Convention also guarantees to person deprived of their liberty further rights: the right to information, the right to appear before a court, the right to compensation and also the right to the respect of privacy and correspondence.
Dystonia‐ataxia syndrome with permanent torsional nystagmus caused by ECHS1 deficiency
Authors: Ronchi Dario , Monfrini Edoardo , Bonato Sara , Mancinelli Veronica , Cinnante Claudia , Salani Sabrina , Bordoni Andreina , Ciscato Patrizia , Fortunato Francesco , Villa Marianna , Di Fonzo Alessio , Corti Stefania , Bresolin Nereo , Comi Giacomo P. 
Published: April 2020

AbstractBiallelic mutations in ECHS1, encoding the mitochondrial enoyl‐CoA hydratase, have been associated with mitochondrial encephalopathies with basal ganglia involvement. Here, we describe a novel clinical presentation consisting of dystonia‐ataxia syndrome with hearing loss and a peculiar torsional nystagmus observed in two adult siblings. The presence of a 0.9‐ppm peak at MR spectroscopy analysis suggested the accumulation of branched‐chain amino acids. Exome sequencing in index probands identified two ECHS1 mutations, one of which was novel (p.V82L). ECHS1 protein levels and residual activities were reduced in patients’ fibroblasts. This paper expands the phenotypic spectrum observed in patients with impaired valine catabolism.
Higher Than 90% Initial Coulombic Efficiency with Staghorn‐Coral‐Like 3D Porous LiFeO2−x as Anode Materials for Li‐Ion Batteries
Authors: Yang Yaxiong , Qu Xiaolei , Zhang Xin , Liu Yongfeng , Hu Jianjiang , Chen Jian , Gao Mingxia , Pan Hongge 
Published: April 2020

AbstractTransition metal oxides represent a promising class of anode materials for high‐capacity lithium‐ion batteries. However, low initial coulombic efficiency (ICE, <80%) still remains a crucial challenge for practical applications. Herein, a unique 3D Fe(II)‐rich porous LiFeO2−x comprising of staghorn‐coral‐like skeleton measuring ≈100 nm in diameter is demonstrated, which is readily prepared by reacting Fe2O3 with LiH at 550 °C. When used as an anode material, the Fe(II)‐rich LiFeO2−x delivers the presently known highest ICE value of 90.2% with 1170 mAh g−1 discharge capacity. The high ICE value can be ascribed to a fast conversion reaction of LiFeO2−x upon lithiation/delithiation facilitated by the presence of Fe(II), which generates oxygen vacancies and makes electron transportation much easier, based on the experimental results and density functional theory (DFT) calculations.
Whole genome duplication does not promote common modes of reproductive isolation in Trifolium pratense
Authors: Porturas Laura D. , Segraves Kari A. 
Published: April 2020

PremiseAlthough polyploidy has been studied since the early 1900s, fundamental aspects of polyploid ecology and evolution remain unexplored. In particular, surprisingly little is known about how newly formed polyploids (neopolyploids) become demographically established. Models predict that most polyploids should go extinct within the first few generations as a result of reproductive disadvantages associated with being the minority in a primarily diploid population (i.e., the minority cytotype principle), yet polyploidy is extremely common. Therefore, a key goal in the study of polyploidy is to determine the mechanisms that promote polyploid establishment in nature. Because premating isolation is critical in order for neopolylpoids to avoid minority cytotype exclusion and thus facilitate establishment, we examined floral morphology and three common premating barriers to determine their importance in generating reproductive isolation of neopolyploids from diploids.MethodsWe induced neopolyploidy in Trifolium pratense and compared their floral traits to the diploid progenitors. In addition to shifts in floral morphology, we examined three premating barriers: isolation by self‐fertilization, flowering‐time asynchrony, and pollinator‐mediated isolation.ResultsWe found significant differences in the morphology of diploid and neopolyploid flowers, but these changes did not facilitate premating barriers that would generate reproductive isolation of neopolyploids from diploids. There was no difference in flowering phenology, pollinator visitation, or selfing between the cytotypes.ConclusionsOur results indicate that barriers other than the ones tested in this study—such as geographic isolation, vegetative reproduction, and pistil–stigma incompatibilities—may be more important in facilitating isolation and establishment of neopolyploid T. pratense.