bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative analysis of current 3D printed acetabular titanium implants
Authors: Dall’Ava Lorenzo , Hothi Harry , Henckel Johann , Di Laura Anna , Shearing Paul , Hart Alister 
Published: November 2019

Abstract

Background
The design freedom allowed by three-dimensional (3D) printing enables the production of acetabular off-the-shelf cups with complex porous structures. The only studies on these designs are limited to clinical outcomes. Our aim was to analyse and compare the designs of different 3D printed cups from multiple manufacturers (Delta TT, Trident II Tritanium and Mpact 3D Metal).

Methods
We analysed the outer surface of the cups using scanning electron microscopy (SEM) and assessed clinically relevant morphometric features of the lattice structures using micro-computed tomography (micro-CT). Dimensions related to the cup wall (solid, lattice and overall thickness) were also measured. Roundness and roughness of the internal cup surface were analysed with coordinate measuring machine (CMM) and optical profilometry.

Results
SEM showed partially molten titanium beads on all cups, significantly smaller on Trident II (27 μm vs ~ 70 μm, p < 0.0001). We found a spread of pore sizes, with median values of 0.521, 0.841 and 1.004 mm for Trident II, Delta TT and Mpact, respectively. Trident II was also significantly less porous (63%, p < 0.0001) than the others (Delta TT 72.3%, Mpact 76.4%), and showed the thinnest lattice region of the cup wall (1.038 mm, p < 0.0001), while Mpact exhibited the thicker solid region (4.880 mm, p < 0.0044). Similar roundness and roughness of the internal cup surfaces were found.

Conclusion
This was the first study to compare the designs of different 3D printed cups. A variability in the morphology of the outer surface of the cups and lattice structures was found. The existence of titanium beads on 3D printed parts is a known by-product of the manufacturing process; however, their prevalence on acetabular cups used in patients is an interesting finding, since these beads may potentially be released in the body.
Delayed administration of recombinant plasma gelsolin improves survival in a murine model of severe influenza
Authors: Yang Zhiping , Bedugnis Alice , Levinson Susan , DiNubile Mark , Stossel Thomas , Lu Quan , Kobzik Lester 
Published: November 2019

Background: Host-derived inflammatory responses contribute to the morbidity and mortality of severe influenza, suggesting that immunomodulatory therapy may improve outcomes. The normally circulating protein, human plasma gelsolin, is available in recombinant form (rhu-pGSN) and has beneficial effects in a variety of pre-clinical models of inflammation and injury. Methods: We evaluated delayed therapy with subcutaneous rhu-pGSN initiated 3 to 6 days after intra-nasal viral challenge in a mouse model of influenza A/PR/8/34. Results: Rhu-pGSN administered starting on day 3 or day 6 increased survival (12-day survival: 62 % vs 39 %, pGSN vs vehicle; p < 0.00001, summary of 18 trials), reduced morbidity, and decreased pro-inflammatory gene expression. Conclusions: Rhu-pGSN improves outcomes in a highly lethal influenza model when given after a clinically relevant delay.
Collaborative Learning Activities through MoE in Engaging EFL Learners and Diminishing their Foreign Language Anxiety
Authors: Fatimah Sitti 
Published: November 2019

Mantle of the Expert (MoE) is an approach integrating drama in learning. A number of studies have proven the approach to be effective in enhancing student’s learning experience and vary teacher’s teaching strategy. This article is drawn from the results of a multi-case study that implemented MoE in EFL teaching in Indonesia. The study involving three cohorts of Grade 11 Indonesian senior and vocational high school students and three English teachers used multiple data collection methods: classroom observation, questionnaire and interview. While questionnaire was distributed to the student participants, the interview was administered to collect the data from teacher participants. The MoE implementation involved a series of drama activities integrated with the lesson topics. During the activities the student participants were assigned several tasks to be completed in small groups. This required students to collaborate. The findings show that these collaborative learning activities has shown positive major impacts, two of them are students’ increased engagement and decreased speaking anxiety.
Errors in English Essay Writing from a Syntactic Perspective
Authors: Hikmah Istianatul 
Published: November 2019

This study discuses errors in English essay writing from syntactic perspective. Syntactic theory was used to analyze data while the data of this study were English essay writing written by university students. The method of this study was qualitative study which was divided into three namely data collecting method, data analysis method, and presentation of data analysis. Data of this study were collected using simak method. It meant monitoring the language used which was in the form of written text. Then there are two techniques used to collect data namely documentation and noted technique. Descriptive analytic was used to analyze data using syntactic theory. Informal method was used to present the result of data analysis in the form of sentences. There were two results of this study. Firstly, it showed that there were nineteen words, thirteen phrases, and thirteen clauses were found as errors in university students’ English essay writing. Secondly, university students need to master English grammar to minimize syntactic errors in English essay writing. Keywords: syntactic errors, syntactic perspective, word, phrase, clause
Exploring the emotions of patients undergoing therapy for hepatitis C
Authors: Montague Sarah , Agarwal Kosh , Cannon Mary 
Published: November 2019

Background: Direct-acting antiviral (DAA) therapy is highly efficacious in the treatment of hepatitis C (HCV). The literature to date has focused primarily on the physical health benefits of viral eradication. Aims: This study explored patient emotions during and after DAA therapy for HCV. Methods: Over a 6-month period, 178 patients attending a viral hepatitis clinic for treatment of HCV were posed a single question: ‘How do you feel about your diagnosis of hepatitis C today?’ Responses were transcribed verbatim, thematically coded and visualised using WordArt software. Findings: The images depict the evolution of patients' perceptions of HCV before, during and after DAA therapy. Responses before treatment were predominantly negative, often describing the fear of contagion and feelings of isolation, secrecy and loneliness. After treatment, patients often described feeling positive and more motivated. Conclusions: The results demonstrate that treatment of HCV has a transformative effect on patients' perception of the impact of HCV on their wellbeing. This may promote a more positive outlook and, in turn, facilitate patient engagement with healthcare.
For the record
Authors: Marshall Kathryn 
Published: November 2019

Kathryn Marshall considers the role of the dental nurse in clinical record keeping Aim By the end of reading this article, the dental nurse will have understood their role in record keeping within the surgery environment. Objectives To enable the dental nurse to understand the importance of good record keeping To begin to understand the advantages and limitations of electronic record keeping To consider the use of ‘prompts’ to assist in standardisation of recording patient data To begin to develop systems and processes for good record keeping GDC development outcomes A
O vocabulário da contrição na Castela do século XV
Authors: Teodoro Leandro Alves 
Published: November 2019

No século XV, com objetivo de purificar os espíritos e reformar as condutas dos fiéis leigos, a cúpula eclesiástica da Coroa de Castela passou a promover, de maneira mais intensa e ordenada, a produção de obras pastorais em língua vernácula. Com ênfase em parte dessa produção, especialmente nos sermões proferidos por Vicente Ferrer em Castela, o alvo deste trabalho consistirá em analisar em que medida esses guias moralizantes ajudaram a naturalizar um vocabulário específico de exercícios voltados para a correção dos pecados. Em outras palavras, este estudo visa questionar a maneira como essas obras procuravam ensinar aos fiéis o papel salutar da contrição nos jogos de redenção das faltas; isto é, do próprio ato de externalização do arrependimento. Partindo dos vocábulos utilizados para nomear as formas de contrição prescritas nesses tempos, outro alvo do trabalho será interrogar como os fiéis poderiam apreender essas palavras e alargar seu vocabulário acerca de termos concernentes ao universo espiritual.
FEATURES OF LIPID COMPOSITION OF SPHAGNUM AND TRUE MOSSES FROM VARIOUS NATURAL CLI-MATIC ZONES
Authors: Serebrennikova Ol'ga Viktorovna , Strel’nikova Evgeniya Borisovna , Russkikh Irina Vladimirovna 
Published: November 2019

A composition of 16 lipid samples of sphagnum and true mosses (Bryales) growing at an average annual temperature ranging from -9.1 °C to 1.5 °C is investigated by gas chromatography-mass spectrometry. The individual composition and content of n-alkanes, fatty n-acids and their esters, n-alkane-2-ones, aldehydes, farnesylfuranes, polycyclic aromatic hydrocarbons (PAHs), tocopherols, squalene, steroids, sesqui-, di- and triterpenoids of these mosses are determined. True mosses differ from sphagnum mosses in their lower content of n-alkanes, n-alkan-2-ones, n-aldehydes, tocopherols and cyclic terpenoids, and a higher content of PAHs. Campesterol prevails among steroids of true mosses, while stigmasterol and sitosterol dominate in sphagnum mosses. Sitosterol prevails in sphagnum mosses growing in areas with a negative average annual temperature. An increase in the temperature of the habitat results in a decrease in the relative content of n-alkanes with odd number of carbon atoms in the molecule in true mosses, and a slight decrease in their average chain length in sphagnum mosses. It is shown that terpenoids are the most dependent on natural habitat conditions of mosses. This is indicated by the content of squalene, sesqui- and diterpenoids, the ratio of hydrocarbons to oxygen-containing structures of cyclic triterpenoids, and that of compounds from series of perhydropicene and cyclopentapeperhydrochryzene. The increased humidity of habitat of a moss eliminates the effect of temperature. The stability of composition of n-alkanes and n-alkan-2-ones of sphagnum mosses developing under various conditions makes it possible to consider these compounds as potential chemotaxonomic markers of sphagnum mosses in peat deposits.
ANTIOXIDANTS IN LIPIDS OF PEATS AND PEAT-FORMING PLANTS
Authors: Yudina Natal'ya Vasil'yevna , Savelieva Anna Viktorovna 
Published: November 2019

The paper presents the results of a study of antioxidant activity of lipids isolated from bioproducer plants and peats sampled from a deposit on spurs of the Vasyugan Swamp. Analysis of antioxidants (AOs) is performed via the gasometric method using a model reaction initiated by cymene oxidation. It is found out that oxidation inhibitors of two types differing in reactivity and antioxidant content are present in peat lipids. In fuscum peats of the same type, the amount of AOs changes insignificantly with an increase in the depth of occurrence. A decrease in AOs of the second type is observed for peats with a high degree of decay.
The experiments on plant humification in a peat deposit conducted during 2 years confirm the neoplasm of AOs of the second type, which is the result of microbiological activity. The content of lipids in plants after 2 years of humification is slightly increased, while the increase in AOs amount exceeding their content in peat lipids of the upper horizon is also observed. The depth of occurrence and the type of peat affect the content of AOs and the O/C ratio, as evidenced by the linear correlation dependence. The relationship between the antioxidant activity of lipids and the C/N ratio is not established.
MINERAL AND AMINO ACID COMPOSITION OF THE LEAVES OF MYRTHUS COMMUNIS L.
Authors: Bakova Ekaterina Yur'yevna , Plugatar Yuriy Vladimirovich , Bakova Nadezhda Nikolayevna , Konovalov Dmitriy Alekseyevich 
Published: November 2019

The homeland of Myrthus communis L. is Mediterranean region, in the countries of which its wild-growing and cultivated varieties grow. In the collection of the Nikitsky Botanical Gardens – National Scientific Center of the Russian Academy of Sciences the economic-valuable and morphological features of nine cultivars of this species have been studied. The plant is considered as a promising industrial medicinal culture.
Contamination of medicinal plants with heavy metals and other toxic elements is an existing problem, which is associated with serious concern of international organizations on the quality and safety of medicinal raw materials.
It is now established that trace constituents, entering into connection with chemical regulators of metabolism, including amino acids, participate in various biochemical processes, stimulate and normalize metabolism.
The objective of this work is to study the elemental and amino acid composition of leaves of Myrthus communis L., cultivated in the Nikitsky Botanical Gardens.
The study of Myrthus communis L. ultimate composition has been done with due regard to General Monograph requirements "The identification of heavy metals and arsenium in medicinal raw materials and plant preparations" for State Pharmacopeia of XIII edition. The research of the amino acid profile has been done subject to State All-Union Standard 32195-2013 (ISO 13903:2005).
As a result of research it has been established that leaves of Myrthus communis L. accumulate 28 elements and 16 amino acids. The content of heavy metals and arsenium in the studied samples did not exceed the maximum permissible values for medicinal plant raw materials established by the Russian State Pharmacopoeia. The total content of amino acids in the leaves of myrtle was 11.65%. Among the amino acids found, glutamic and aspartic acids prevailed. The least in the leaves was methionine. The obtained results will be used for follow up standardization of myrtle raw materials as a promising source of medicinal plant raw material.
THE STUDY OF PHYSICO-TECHNOLOGICAL FACTORS’ INFLUENCE ON THE OUTPUT OF LIPOPHILIC SUB-STANCES FROM MEDICINAL PLANT MATERIALS
Authors: Degtyareva Ekaterina Aleksandrovna , Vyshnevska Liliya Ivanovna , Garnaya Svetlana Vasil'yevna , Kalko Ekaterina Aleksandrovna 
Published: November 2019

Currently, the lipophilic fractions of well-known medicinal plants are still understudied despite of contains of unique groups of BAS (chlorophylls, carotenoids, tocopherols, sterols, unsaturated fatty acids, phospholipids, etc.), what is the actual task of modern pharmaceutical science. The aim of our work was to perform experimental studies for the choice of optimal conditions of the extraction of lipophilic compounds from the meal of pumpkin pulp. Extraction of lipophilic substances from the meal of pumpkin pulp was carried out in laboratory conditions in the Soxhlet apparatus by the method of circulation extraction. The weight loss on drying, the content of extractive lipophilic substances and the amount of carotenoids (in terms of β-carotene) were determined by compendial procedures. According to the results of the experimental work, the optimum humidity (not more than 7%) and drying temperature (+ 60 °C) of pumpkin pulp meal containing carotenoids were established. The obtained data are necessary for the development of technology of lipophilic pumpkin extract.
LIPID COMPOSITION AND MEMBRANOPROTECTIVE ACTION OF EXTRACT FROM MARINE GREEN ALGAE ULVA LACTUCA (L.)
Authors: Fomenko Svetlana Yevgen'yevna , Kushnerova Natal'ya Fedorovna , Sprygin Vladimir Gennad'yevich , Drugova Elena Sergeyevna , Lesnikova Larisa Nikolayevna , Merzluakov Valeriy Yur'yevich 
Published: November 2019

The object of the present study was a water-alcohol extract obtained from the dried thallus of the marine green alga Ulva lactuca (L.) (syn.: Ulva fenestrate P. et R.) – ulva lettuce. Glycolipids (40.6%) and neutral lipids (34%) prevailed in the lipid fraction of the extract; phospholipids contained 13.4% of the total lipids. The content of polyunsaturated fatty acids (PUFA) was 50% of the total amount of fatty acids, among which PUFA of the n-3 family predominated (37.43%). On the model of toxic hepatitis induced by the introduction of carbon tetrachloride (CCl4) (50% solution in olive oil, subcutaneously 2 ml/kg for 4 days), we study the effect of the lipid fraction of U. lactuca extract and the commercial reference preparation Essentiale® on the physiological and biochemical characteristics of erythrocytes and lipid composition of erythrocyte membranes in rats. The introduction of the lipid fraction from the ulva (dose 80 mg of total lipids per kg of body weight) to the animals intragastrically for 7 days after withdrawal of CCl4 exerted a protective effect, which was manifested in the restoration of the erythrocyte size characteristics (average volume and diameter), their osmotic resistance to hemolysis, levels of malondialdehyde and reduced glutathione, as well as maintaining of the ratio of phospholipid fractions. Under the damaging effects of CCl4, the lipid fraction from the green alga U. lactuca was not inferior to the effectiveness of reference preparation Essentiale® in restoring of the physiological characteristics of erythrocytes and the phospholipid composition of its membranes.
METABOLOMIC PROFILE BUPLEURUM SCORZONERIFOLIUM WILLD., GROWING IN THE BAIKAL REGION
Authors: Petukhova Svetlana Andreyevna , Olennikov Daniil Nikolayevich , Mirovich Vera Mikhaylovna 
Published: November 2019

In folk medicine in the Baikal region, an infusion from the aerial part of the plant Bupleurum scorzonerifolium (Willd) is widely used as a choleretic and anti-inflammatory agent. The choleretic effect of herbal remedies is mainly due to the content of phenylpropanoids and flavonoids. Using high performance liquid chromatography with a diode-matrix detector and 3Q electrospray ionization detector, we studied the metabolic profile of the phenylpropanoids and flavonoids of the aboveground organs of B. scorzonerifolium (Willd.), which grows in the Baikal region. In the aboveground organs of B. scorzonerifolium, 7 phenylpropanoids and 17 flavonoids were identified, of which 15 compounds for the species were identified for the first time. Quantitative determination of individual components was carried out in the aboveground organs of B. scorzonerifolium and dry extract by microcolumn HPLC with UV detection. The predominant components in the aerial part of the plant are 5-O-caffeic quinic acid, 3,5-di-O-caffeic quinic acid, isoquercitrin, isorhamnetin-3-O-glucoside, kaempferol-3-O-rhamnoside and rutin. The dry extract obtained from the aerial part of B. scorzonerifolium contains the entire complex of phenylpropanoids and flavonoids, which are identified in the plant. The content of active ingredients in the extract is 2.5–3.0 times higher than in the aboveground organs. The aboveground organs and dry extract of B. scorzonerifolium can be used as a source of phenylpropanoids and flavonoids.
PERÚ Y LA ESTRATEGIA ARMADA EN LOS AÑOS SESENTA: LA REACTUALIZACIÓN DE UN DEBATE
Authors: MANGIANTINI MARTÍN 
Published: November 2019

A principios de los años sesenta, la organización trotskista argentina Palabra Obrera decidió el envío de tres militantes al Perú con el objetivo de construcción e inserción política en un contexto de importante convulsión social, principalmente a partir de la toma de tierra y la sindicalización campesina en la región del Cuzco. La puesta en práctica de acciones armadas por parte de este grupo generó un proceso de discusión y debate que, recientemente, se trajo a colación a raíz de una serie de nuevos insumos documentales. Es objetivo de este artículo analizar este hecho a la luz de estas flamantes herramientas de discusión.
TRAYECTORIAS DE POLITIZACIÓN: LA ESTRATEGIA DEL SINDICATO CERAMISTA NEUQUINO, 2001-2003
Authors: AIZICZON FERNANDO 
Published: November 2019

Este trabajo se aproxima al estudio del proceso de lucha del sindicato ceramista de Neuquén (SOECN) entre la crisis sociopolítica del año 2001 hasta fines del año 2003. Dicho proceso, que denominamos trayectoria de politización, permite discutir las transformaciones que atraviesan los trabajadores en el transcurso de una lucha política que posibilita la construcción de estrategias y acciones innovadoras abriendo la discusión sobre la función de la organización sindical más allá del sindicato.
LUCHAS INTERNAS EN LA ZONA FRANQUISTA DURANTE LA GUERRA CIVIL
Authors: THOMÀS JOAN MARIA 
Published: November 2019

El presente artículo analiza las tensiones políticas internas producidas en la zona franquista oEspaña “nacional” durante la Guerra Civil española (1936-1939). Partiendo de la diversidad de la coalición autoritaria o bloque político y social de los alzados contra la Segunda República, estudia dicha conflictividad atendiendo a los diferentes proyectos políticos en concurrencia, así como las tensiones entre los dos partidos ultraderechistas dominantes -Falange Española de las JONS (fascista) y Comunión Tradicionalista (carlista)- y el poder franquista. Analiza igualmente la gestación de la unificación imperativa e incautación de los dos partidos citados por el Generalísimo para crear el partido único de su régimen, Falange Española Tradicionalista y de las JONS, así como la de la ley fundamental promulgada durante la contienda, el llamado Fuero del Trabajo.
CONOCIMIENTO, REPRESENTACIONES Y COMPORTAMIENTOS SOCIALES EN TORNO A LA “MASACRE DE TRELEW” EN BAHÍA BLANCA Y PUNTA ALTA (AGOSTO-NOVIEMBRE 1972)
Authors: DOMINELLA VIRGINIA 
Published: November 2019

Si bien la “Masacre de Trelew” sacudió a todo el país, Bahía Blanca y Punta Alta se vieron movilizadas en forma particular por diversas razones. Una de ellas fue la cercanía de los sobrevivientes y sus familiares. Este artículo aborda la elaboración de conocimiento, la circulación de información y la conformación de representaciones sobre el acontecimiento de Trelew en dichas ciudades en las horas, los días y las semanas posteriores a los hechos. Asimismo, analiza las actitudes y los comportamientos asumidos frente a ellos por diversos actores locales. ¿Qué informaciones circularon sobre la Masacre” y cómo? ¿Qué pudo conocerse de aquélla? ¿Qué rol ocupó la prensa local y los familiares de los sobrevivientes? ¿Qué sentidos se construyeron sobre el acontecimiento? ¿Cómo reaccionaron los abogados defensores de presos políticos, los sectores estudiantiles, los católicos liberacionistas y los colectivos artísticos militantes?
D. EUGÊNIO SALES NA ARQUIDIOCESE DE SALVADOR EM TEMPOS DE DITADURA MILITAR
Authors: CARNEIRO ZACHARIADHES GRIMALDO 
Published: November 2019

Este artigo analisará a atuação do arcebispo D. Eugênio de Araújo Sales na arquidiocese de São Salvador, no estado da Bahia, região Nordeste do Brasil, entre os anos de 1964 e 1971. Ele assumiu a arquidiocese em um período de crescimento econômico acelerado no Brasil, e na Bahia em particular, e de recrudescimento político com a instauração e consolidação da Ditadura Militar (1964-1985). Ele foi responsável pela reestruturação da arquidiocese, mas teve conflitos com membros do clero e leigos pela sua relação com o Regime Militar.