bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nomogram-Based Preoperative Score for Predicting Clinical Outcome in Unilateral Primary Aldosteronism
Authors: Yang Yi , Williams Tracy Ann , Song Ying , Yang Shumin , He Wenwen , Wang Kanran , Cheng Qingfeng , Ma Linqiang , Luo Ting , Yang Jun , Reincke Martin , Burrello Jacopo , Li Qifu , Mulatero Paolo , Hu Jinbo 
Published: September 2020

Abstract

Context
More than half of patients diagnosed with unilateral primary aldosteronism (UPA) suffer from persisting hypertension after unilateral adrenalectomy.

Objective
The objective of this work is to develop and validate a nomogram-based preoperative score (NBPS) to predict clinical outcomes after unilateral adrenalectomy for UPA.

Design and Setting
The NBPS was developed in an Asian cohort by incorporating predictors independently associated with remission of hypertension after unilateral adrenalectomy for UPA and validated in a Caucasian cohort.

Participants
Participants comprised patients with UPA achieving complete biochemical success after unilateral adrenalectomy.

Main Outcome Measure
Measurements included the predictive performance of the NBPS compared with 2 previously developed outcome prediction scores: aldosteronoma resolution score (ARS) and primary aldosteronism surgical outcome (PASO) score.

Results
Ninety-seven of 150 (64.7%) patients achieved complete clinical success after unilateral adrenalectomy in the training cohort and 57 out of 165 (34.5%) in the validation cohort. A nomogram was established incorporating sex, duration of hypertension, aldosterone-to-renin ratio, and target organ damage. The nomogram showed good C indices and calibration curves both in Asian and Caucasian cohorts. The area under the receiver operating characteristic curve (AUC) of the NBPS for predicting hypertension remission in the training cohort was 0.853 (0.786-0.905), which was superior to the ARS (0.745 [0.667-0.812], P = .019) and PASO score (0.747 [0.670-0.815], P = .012). The AUC of the NBPS in the validation cohort was 0.830 (0.764-0.884), which was higher than the ARS (0.745 [95% CI, 0.672-0.810], P = .045), but not significantly different from the PASO score (0.825 [95% CI, 0.758-0.880], P = .911).

Conclusion
The NBPS is useful in predicting clinical outcome for UPA patients, especially in the Asian population.
Staging the Tumor and Staging the Host: Pretreatment Combined Neutrophil Lymphocyte Ratio and Modified Glasgow Prognostic Score Is Associated with Overall Survival in Patients with Esophagogastric Cancers Undergoing Treatment with Curative Intent
Authors: McSorley Stephen T. , Lau Hiu Y. N. , McIntosh David , Forshaw Matthew J. , McMillan Donald C. , Crumley Andrew B. 
Published: September 2020

Abstract
Background
This study examined whether an innate systemic inflammatory response (SIR) measured by combination neutrophil to lymphocyte ratio (NLR) and modified Glasgow Prognostic Score (mGPS) was associated with overall survival (OS) in patients with esophagogastric cancer (EC) undergoing neoadjuvant chemotherapy (NAC) followed by surgery.

Methods
Patients diagnosed with EC, managed with NAC prior to surgery at a regional referral center, between January 2010 and December 2015, were included. The mGPS and NLR were calculated within 12 weeks before NAC. Patients were grouped by combined NLR/mGPS score into three groups of increasing SIR: NLR ≤ 3 (n = 152), NLR > 3 + mGPS = 0 (n = 55), and NLR > 3 + mGPS > 0 (n = 32). Univariable and multivariable Cox regression was used to analyse OS.

Results
Overall, 337 NAC patients were included, with 301 (89%) proceeding to surgery and 215 (64%) having R0 resection. There were 203 deaths, with a median follow-up of those alive at censor of 69 months (range 44–114). Higher combined NLR/mGPS score (n = 239) was associated with poorer OS independent of clinical stage and performance status (hazard ratio 1.28, 95% confidence interval 1.02–1.61; p = 0.032), higher rate of progression on NAC (7% vs. 7% vs. 19%; p = 0.003), and lower proportion of eventual resection (80% vs. 84% vs. 53%; p = 0.003).

Conclusions
The combined NLR/mGPS score was associated with OS and initial treatment outcomes in patients undergoing NAC prior to surgery for EC, stratifying survival in addition to clinical staging and performance status. The host SIR may be a useful adjunct to multidisciplinary decision making.
Advancing the sensitivity of integrated epoxy-based Bragg grating refractometry by high-index nanolayers
Authors: Hessler Steffen , Knopf Stefan , Rommel Mathias , Girschikofsky Maiko , Schmauss Bernhard , Hellmann Ralf 
Published: September 2020

In this Letter, we report on significantly improved surrounding RI sensitivity of epoxy polymer waveguide Bragg grating sensors. Uniform Bragg gratings were generated inside flat rectangular epoxy waveguides near the cutoff regime using standard phase mask excimer laser writing. Thickness controlled nanolayers of high-index titanium dioxide were deposited homogeneously on the waveguide sensor’s surface area by repeated reactive sputter processing. Maximum Bragg wavelength shifts as high as 74.22 nm, as well as maximum sensitivities around 523 nm/RI unit corresponding to a minimum RI resolution of

1.9

⋅

1

0

−
6

, could be obtained by employing a

∼

75

n
m

thick titanium dioxide coating.
Enhanced resonant vibrational Raman scattering of N2+ induced by self-seeding ionic lasers created in polarization-modulated intense laser fields
Authors: Li Guihua , Xie Hongqiang , Zhang Qian , Lei Hongbin , Zhou Xingyu , Wang XiaoWei , Chen Zhiming , Zhao Zengxiu 
Published: September 2020

We report on an experimental investigation of the five vibrational Raman lines at 358 nm, 388 nm, 391 nm, 428 nm, and 471 nm of

N

2
+

resonantly driven by the self-seeding ionic lasers generated by a polarization-modulated (PM) or alternatively a linearly polarized (LP) femtosecond laser. It was found that the spectral intensities of several Raman lines can be dramatically enhanced by exploiting the PM laser pulses in comparison to the LP laser pulses. The evaluated Raman conversion efficiency reaches

∼

1

0

−
2

for some lasing lines at suitable pressures. Moreover, the role of interplay between the seed amplification and the resonant vibrational Raman scattering processes in inducing the gain of

N

2
+

lasing is characterized for the first time. The developed vibrational Raman spectroscopy with intense ultrafast lasers provides an additional approach to interrogate the products in a femtosecond filament, and it therefore can be a powerful tool for identifying chemical species at remote distances in the atmosphere.
Comparative Results of Regional and Residual Anomalies with the Upward Continuation, Moving Average, and Polynomial Methods for Magnetic Data
Authors: Indrawati Luvera Deva Intan , Indriana Rina Dwi , Nurwidyanto Irham 
Published: September 2020

Geophysics programing of regional and residual anomaly separation on Magnetic data has been carried out with the results compared with the upward continuation method in the OasisMontaj software. Separation of anomalies with moving average and polynomial methods is processed using Matlab programming. The orders used in the polynomial method are first-order, second-order and third-order. Comparison is done by calculating the match value. The chosen matching method is autocorrelation. Correlation of residual magnetic anomalies resulting from upward continuation (Magpick) to moving averages, 1st-order polynomials, 2nd-order polynomials and 3rd-order polynomials. Correlation values obtained for the moving average method are 0.9604, first order polynomial 0.9072, 2nd order polynomial 0.9482 and third order polynomial 0.6057. The moving average and second order polynomial methods can be used as a substitute method if we do not use the upward continuation method.
Bistriopelma fabianae, a new species of tarantula (Araneae: Theraphosidae: Theraphosinae) in a Queñua forest from southern Peru
Authors: Quispe-Colca Oscar Magdiel , Kaderka Radan 
Published: September 2020

A new species of Bistriopelma Kaderka 2015, Bistriopelma fabianae sp. nov., from the Arequipa region in southern Peru is described, diagnosed, and illustrated. Specimens were found in a Queñua forest (Polylepis rugulosa Bitter) spread out on the slopes of Pichu Pichu volcano in the buffer zone of Salinas and Aguada Blanca National Reserve. Biological and ecological data of B. fabianae sp. nov. are provided as well as notes on B. kiwicha and B. peyoi, two new species recently described from Apurimac and Cusco regions.
Publicación registrada en Zoobank/ZooBank article registered:LSIDurn:lsid:zoobank.org:pub:BB9DF4D9-6684-46AF-9D15-71FEC64CD032Acto nomenclatural/nomenclatural act:Bistriopelma fabianae Quispe-Colca and Kaderka, 2020LSIDurn:lsid:zoobank.org:act:B63485CD-C00D-4E93-AF02-914AD9A566DA
Indonesia–English Translation of Idiomatic Expressions in The Novel This Earth of Mankind
Authors: Dwi Floranti Astri , Mubarok Yasir 
Published: September 2020

The study investigated Indonesia–English translation of idiomatic expressions, focusing on the idioms, in one of Indonesian best seller fiction story, Bumi Manusia which was translated into English as This Earth of Mankind. The study identified the types of the translation strategies by the translators to reproduce the idioms from SL in TL and the accuracy level of their latest meanings in TL. Qualitative research method in the design of content analysis was employed. The result portrayed that the most dominant strategy employed by the translator was paraphrasing. The translator reproduced the original meaning of the idioms by selecting common vocabularies in TL (non-idiom forms) that shared identical meanings with the idioms in SL or explaining the idioms in SL at longer statements in TL. The other idioms could be translated equivalently in the form of idioms in TL, but they were realized in different lexical words from SL. Furthermore, most of idioms achieved equivalent meanings, but decreased meanings were unavoidable. Thus, it can be seen that the translator attempted to recreate the similar equivalence meaning of the idioms from SL through paraphrasing strategy instead of omitting the idioms in TL. Most of the translated idioms could be reproduced similarly with the original idioms.
Literature and Society: Singir's Structure and Function for the Javanese Santri Community
Authors: Islam M. Adib Misbachul , Rokhim Minatur , Fadlan Muhammad Nida' 
Published: September 2020

AbstractThis article aimed to examine the structure of Javanese singir as an adaptation work of poetry tradition originating from outside Javanese culture and its function for the reading community. This study compared the six Javanese singirs of the library of Universitas Indonesia (Singir Ahli Suwarga, Singir Dagang, Singir Kiamat, Singir Nasihat Jaman Akhir, Singir Patimah, and Singir Santri) with some Arabic and Malay poetry and then discussed them in the social context of Javanese coastal communities. Through a comparative structural approach and sociological studies, this article found that Javanese singir was structurally linked with Arabic poetry rather than with Malay poetry. This could be found in the metrum system which was close to the metrum of kamil majzu’, and various rhyming patterns which were a combination of murabba’ rhyme and muzdawij. The influence of Malay poetry in the six singirs seemed to have little effect, which was limited to aspects of the rhyme pattern a-a-a-a, b-b-b-b that were not fully used. Through an examination of the connection between the six singirs and the reading community, this article also found that there were two functions of singir; entertaining, and didactic functions that taught various social and religious aspects to the Javanese santri community.
Vagrants’ Communication Behavior in Interpersonal Relations in Jakarta
Authors: Rohim Syaiful 
Published: September 2020

Abstract The study aimed to know the communication management pattern of interpersonal communicationactivities among vagrants and other communities. The study made use of qualitative researchintended to get complete description of interpersonal communication phenomena that occurredamong vagrants and other communities. The research relied on observation and in-depth interviewswith ten vagrants which were spread in some places in Jakarta, Depok, Tangerang Selatan,Tangerang, Bogor, and Bekasi. The collected data were analyzed using Johari Window theory toexplain which frame underlay how vagrants conducted interpersonal and intrapersonalcommunication. The result showed that vagrants did their communication activities by dividingthemselves into open and close areas. The other communication behavior was done throughmechanism management of impression which was made to manage and organize how to behave ininterpersonal communication and relation with others as a form of adaptation and an effort to keepharmony in social interaction and communication. It can be concluded that the vagrants are part ofthe social system and structure of the community that has traditions and culture that need to berespected and appreciated. Keywords: vagrant; self; impression management, Johari Window
Islamic Education and Islamization Channels in Malay Peninsula in 7th-8th Centuries AD
Authors: Nurbaiti Nurbaiti , Suparta Mundzier , Azwar Muhammad 
Published: September 2020

This study aimed to discuss the role of Islamization channels in the process of entry and spread of Islam in Malay Peninsula in seventh to eighth century AD. The research used qualitative method with a descriptive analytical approach. By taking data through interview, journals and textbooks, then conducting a description and analysis of the data, the results showed that the process of Islamization in Malay Peninsula in seventh to eighth centuries AD was carried out through several channels, namely trade, marriage, Sufi, politics, education, and arts. The study also showed that Islamic education functioned as the main channel in the process of Islamization. The role of Islamic education was mainly enhancing Muslims’ understanding about Islam which was implemented informally and non-formally. Informal education occurred through the interaction between the ulama and community carrying out everyday lives; while, nonformal education was conducted by holding learning activities in the mosque through small groups known as halaqah. The study concluded that Islamic education was the main channel of the Islamization process in Malay Peninsula.
Enseñanza del alemán a personas ciegas
Authors: Curmen-Rojas Ernesto Atahualpa 
Published: September 2020

La experiencia investigativa que se presenta a continuación tiene como fin contribuir en el estudio de procesos didácticos que favorezcan el aprendizaje del idioma alemán en la población ciega. Este tipo de población tiende a ser dejada de lado en muchos ámbitos no sólo académicos sino profesionales, por la escasa capacitación docente, la falta de adecuación de los contenidos educativos, del currículo, del sistema evaluativo y de los espacios de aprendizaje. También influyen presuposiciones de ciertos grupos sociales o la indiferencia e irrelevancia que se ejerce sobre el que tiene condiciones sensoriales diferentes, obstáculos que la población mencionada debe sortear constantemente. Por ello, esta investigación de carácter mixto nació como una posibilidad de asumir el reto de trabajar con personas ciegas que requieren elementos pedagógicos y didácticos que van más allá de los que usualmente se enseñan en las carreras de filología. En la experiencia investigativa se utiliza el sistema de escritura braille como punto de apoyo principal para el desarrollo de las sesiones, cuyos contenidos se estructuraron de acuerdo con las cuatro habilidades sugeridas por el Marco Común Europeo de Referencia para las Lenguas (mcer): Comprensión oral, comprensión escrita, producción escrita y producción e interacción oral. Así mismo, se realizó un examen que evaluó estas habilidades comunicativas al final de las sesiones con los estudiantes participantes de esta investigación, evidenciando que el conocimiento del idioma alemán puede ser altamente accesible para la población que tiene limitación visual. Los aportes de esta investigación muestran la necesidad imperante de tener en cuenta a poblaciones con necesidades educativas especiales (como la ciega) en la adaptación de los procesos de planeación, diseño curricular y en las prácticas evaluativas. Este trabajo también amplía el marco de acción en la enseñanza de lenguas extranjeras dada la escasa investigación que existe alrededor de esta temática.
Factores Genéticos y Epigenéticos en la Patogénesis de la Dermatitis Atópica
Authors: Sandì Grettchen Flores 
Published: September 2020

La Dermatitis Atópica es la enfermedad cutánea de mayor prevalencia a nivel mundial, pertenece al grupo de trastornos con características comunes de sensibilización alergénica, anomalías de barrera epitelial y respuestas inmunitarias de tipo 2. Objetivo General: Investigar los principales factores genéticos y epigenéticos en la patogénesis de esta enfermedad. Resultados: Las diferentes investigaciones han permitido demostrar que la dermatitis atópica es una enfermedad con alta heredabilidad y fenotipos clínicos heterogéneos, lo que se justifica precisamente por mecanismos genéticos asociados a la reciprocidad de efectos
inmunológicos y epidérmicos, influenciados por factores epigéneticos. El factor de riesgo genético conocido más fuerte es la presencia de mutaciones nulas en FLG, sin embargo, las mutaciones de este gen no son necesarias ni suficientes. Discusión: La terapia génica para el tratamiento de la dermatitis atópica, si bien ha sido postulada, debe considerarse con reserva, pues los anticuerpos monoclonales no constituyen con el grado de conocimiento actual una solución definitiva, dados todos los mecanismos implicados y las diferentes expresiones de la enfermedad. En este contexto los conceptos de bioética y asesoría genética adquieren relevancia. Conclusiones: Si bien desde el punto de vista de las ciencias forenses, la descripción de alterciones genéticas específicas en una persona o grupo de personas puede permitir su identificación genética o filiación biológica a un grupo; además para el médico forense el posible desarrollo de terapéutica especifica que puede variar el pronóstico de patologías crónicas discapacitantes podría asociarse a los conceptos de “agotamiento del recurso terapéutico” y “judicialización de la medicina”
Generalidades de Enfermedad Celiaca y abordaje diagnóstico
Authors: Murillo Saviano José Alfredo , Piedra Carvajal Willian , Sequeira Calderón Daniela , Sánchez Más Ellen Sylvie , Sandoval Loría Daniel Andrés 
Published: September 2020

La enfermedad celiaca (EC), es una intolerancia permanente al gluten, con una prevalencia del 1%, la cual aumenta en personas con enfermedades autoinmunes, cromosomopatías, o familiares en primer grado con EC. Clínicamente puede cursar desde asintomática, hasta producir un síndrome de malabsorción florido con síntomas gastrointestinales y extra gastrointestinales, con afectación del estado nutricional. El diagnóstico se realiza basándose en la sospecha clínica, pruebas serológicas, estudios genéticos (HLA DQ2/8) y el Gold standar para el diagnóstico, el cual es la biopsia duodenal. El tratamiento una vez confirmado el diagnóstico, es mantener una dieta libre de gluten de por vida.
Manejo Quirúrgico del Prolapso Rectal
Authors: Rockbrand Campos Leyla Priscilla 
Published: September 2020

El prolapso rectal es una patología poco frecuente, de fisiopatología no clara; pero que incluye un trastorno del piso pélvico; además es una enfermedad con un gran impacto en el estilo de vida de los pacientes que lo padecen.
Típicamente ocurre en mujeres adultas mayores, pero puede ocurrir en hombres y mujeres de todas las edades. Dentro de las manifestaciones clínicas más frecuentes se incluyen la incontinencia fecal, estreñimiento y la sensación de masa rectal. El diagnóstico puede hacerse únicamente por examen físico o bien, en casos sospechosos puede confirmarse con una defecografía; a su vez, se pueden realizar múltiples estudios complementarios dentro de los que se encuentran: Resonancia Magnética,cistografía,tránsito colónico, manometría anal, latencia del motor terminal del nervio pudendo y una colonoscopia. El envío de estos estudios debe valorarse en forma independiente en cada caso.
La piedra angular del tratamiento del prolapso rectal es la cirugía con abordaje abdominal, por su mayor efectividad; o en su defecto, el abordaje perineal. A pesar de ser el tratamiento de elección, a todos los pacientes se les debe instruir de forma inicial sobre el manejo médico, ya que, se disminuyen los síntomas y es posible mejorar la calidad de vida del paciente.
Complications and risk factors regarding the outcomes of canine babesiosis in Central Europe – A retrospective analysis of 240 cases
Authors: Strobl Anja , Künzel Frank , Tichy Alexander , Leschnik Michael 
Published: September 2020

AbstractThe purpose of this study was to investigate retrospectively the prevalence of the complicated and uncomplicated forms of babesiosis and to evaluate various laboratory and clinical parameters of dogs infected with Babesia canis in order to assess their prognostic value regarding the outcomes of the disease. Medical records, complete blood count and serum biochemical analysis from the animal hospital information system of 240 dogs were reviewed and evaluated retrospectively. Binary logistic regression analysis was used to ascertain correlations between alterations in the obtained parameters and survival probability. The results showed that creatinine levels of more than 5 mg/dL and phosphate levels of more than 3 mmol/L have a highly significant link to death (P ≤ 0.001). Albumin levels of <2.2 g/dL (P = 0.003) and a rectal body temperature below 38 °C (P ≤ 0.001) may also serve as prognostic markers for the severity of the disease. If renal involvement was present, 33.9% of the dogs died, while 40.0% of the dogs died in the presence of pancreatitis. The parameters creatinine, phosphate, albumin and rectal temperature serve as reliable predictive markers of an increased risk of death in the case of an infection with B. canis.