bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flow chemistry controls self-assembly and cargo in Belousov-Zhabotinsky driven polymerization-induced self-assembly
Authors: Hou Liman , Dueñas-Díez Marta , Srivastava Rohit , Pérez-Mercader Juan 
Published: December 2019

AbstractAmphiphilic block-copolymer vesicles are increasingly used for medical and chemical applications, and a novel method for their transient self-assembly orchestrated by periodically generated radicals during the oscillatory Belousov-Zhabotinsky (BZ) reaction was recently developed. Here we report how combining this one pot polymerization-induced self-assembly (PISA) method with a continuously stirred tank reactor (CSTR) strategy allows for continuous and reproducible control of both the PISA process and the chemical features (e.g. the radical generation and oscillation) of the entrapped cargo. By appropriately tuning the residence time (τ), target degree of polymerization (DP) and the BZ reactants, intermediate self-assembly structures are also obtained (micelles, worms and nano-sized vesicles). Simultaneously, the chemical properties of the cargo at encapsulation are known and tunable, a key advantage over batch operation. Finally, we also show that BZ-driven polymerization in CSTR additionally supports more non-periodic dynamics such as bursting.
Aneurysmenbehandlung mithilfe der Methode des Endovascular aortic Repair
Authors: Pöttgens Nina 
Published: December 2019

AbstractIn diesem Artikel wird ausführlich die Bedeutung des Endovascular aortic Repair besprochen. Die einem Aneurysma zugrunde liegenden Gefäßproblematiken und Risikofaktoren werden erörtert. Anschließend wird die Indikationsstellung, die Patientenvorbereitung und die Methodik bzw. deren Komplikationen dargestellt.
Die Würde des Menschen ist unantastbar –
Gesundheit/Gesundheitsversorgung ist ein Menschenrecht
Authors: Trabert Gerhard 
Published: December 2019

ZusammenfassungDie Preisträgerrede behandelt die Rolle
Gesundheit/Gesundheitsversorgung als Menschenrecht in Deutschland im 21.
Jahrhundert und die daraus resultierenden Konsequenzen für
gegenwärtiges persönliches und politisches Handeln.
Identität und Integration – Salomon Neumann zur Syphilisfrage in Berlin
Authors: Gostomzyk Johannes G. 
Published: December 2019

ZusammenfassungDie Schrift „Die Berliner Syphilis Frage. Ein Beitrag zur öffentlichen Gesundheitspflege Berlins“ unterstreicht in die Bedeutung von Salomon Neumann als einen Initiator der Sozialmedizin und Förderer der kommunalen Medizinalstatistik in der Mitte des 19 Jahrhunderts. Als Arzt des Berliner Gesundheitspflege-Vereins und Armenarzt gibt er einen für die Prävention und die Gesundheitsversorgung prospektiv orientierten sozialmedizinischen Bericht zu den Wechselwirkungen zwischen der Krankheit Syphilis und der Gesellschaft mit ihren ordnungsrechtlich-reglementierenden Maßregeln (Sittenpolizei, öffentliche Verwaltung) und den unzureichenden Strukturen der öffentlichen Gesundheitspflege sowie der defizitären ambulanten und stationären Gesundheitsversorgung armer Menschen in Berlin in der Mitte des 19. Jahrhunderts.
MiR-203a-3p targets PTEN to promote hepatocyte proliferation by regulating PI3K/Akt pathway in BRL-3A cells
Authors: Zhang Yingzi , Zheng Yunping , Zhu Guanmei 
Published: December 2019

ABSTRACT
This study was designed to investigate the role of miR-203a-3p in hepatocyte proliferation. Data analysis showed that up-regulation of miR-203a-3p increased the cell viability and cell proliferation, and inhibited apoptosis. Further experiments demonstrated that PTEN was a target gene of miR-203a-3p, and miR-203a-3p targeted PTEN to regulate the above functions. Overexpression of PTEN partially reversed the inhibition of PTEN and the activation of p-Akt/Akt induced by miR-203a-3p mimic. Our study revealed that miR-203a-3p might activate PI3K/Akt signaling pathway by inhibiting PTEN expression, thereby promoting cell proliferation.
High Luminosity LHC Optics and Layout HLLHCV1.4
Authors: Maria R De , Bruce R , Gamba D , Giovannozzi M , Plassard F 
Published: December 2019

Abstract
The goal of the High Luminosity Project is the upgrade of the LHC to deliver an integrated luminosity of at least 250 fb-1 per year in each of the two high-luminosity, general-purpose detectors ATLAS and CMS. This article presents the latest layout design and the corresponding optics features, which comprise optimisation of the orbit corrector and crab cavity systems, and new estimates of the performance reach thanks to the new concept of fully remote alignment. In addition, the new optics version incorporates improvements required by beam instrumentation, dump system, and collimation system, as well as low-beta solutions for the LHCb experiment.
Collimation system studies for the FCC-hh
Authors: Bruce R , Abramov A , Bertarelli A , Besana M I , Carra F , Cerutti F , Faus-Golfe A , Fiascaris M , Gobbi G , Krainer A , Lechner A , Mereghetti A , Mirarchi D , Molson J , Pasquali M , Redaelli S , Schulte D , Serluca M , Skordis E , Varasteh M 
Published: December 2019

Abstract
The Future Circular Collider (FCC-hh) is being designed as a 100 km ring that should collide 50 TeV proton beams. At 8.3 GJ, its stored beam energy will be a factor 28 higher than what has been achieved in the Large Hadron Collider, which has the highest stored beam energy among the colliders built so far. This puts unprecedented demands on the control of beam losses and collimation, since even a tiny beam loss risks quenching superconducting magnets. We present in this article the design of the FCC-hh collimation system and study the beam cleaning through simulations of tracking, energy deposition, and thermo-mechanical response. We investigate the collimation performance for design beam loss scenarios and potential bottlenecks are highlighted.
Monitoring and Modelling of the LHC Emittance and Luminosity Evolution in 2018
Authors: Papadopoulou S. , Antoniou F. , Efthymiopoulos I. , Hostettler M. , Iadarola G. , Karastathis N. , Kostoglou S. , Papaphilippou Y. , Trad G. 
Published: December 2019

Abstract
Operating at 6.5 TeV, the LHC surpassed the expectations and delivered an average of 66 fb–1 integrated luminosity to the two high luminosity experiments ATLAS and CMS by the end of 2018. In order to provide a continuous feedback to the machine coordination for further optimizing the performance, an automated tool for monitoring the main beam parameters and machine configurations, has been devised and extensively used. New features like the coupling between the two planes and effects of noise, were added to the numerical model used since 2016 to calculate the machine luminosity. Estimates, based both on simulations and on observed beam parameters, were reported fill-by-fill as well as in overall trends during the year. Highlights of the observations including the observed additional emittance blow up (on top of IBS, SR and elastic scattering) as well as additional losses (on top of the expected proton burn off) are presented for the 2018 data. Finally, cumulated integrated luminosity projections from the model for the entire 2018 data based on different degradation mechanisms are compared also with respect to the achieved luminosity.
Design study of an electron storage ring for the future plan of Hiroshima Synchrotron Radiation Center
Authors: Matsuba S. , Shimada K. , Katoh M. , Kawase K. , Harada K. 
Published: December 2019

Abstract
We present the latest result from the design study for the future plan of Hiroshima synchrotron radiation center (HSRC). The design goal is the energy of around 500 MeV, the circumference shorter than 50 m and the emittance smaller than 10 nm with straight sections for undulators more than 4. We have selected the lattice structure similar to ASTRID 2 compact light source in Aarhus University, Denmark.
Design Status of DESY IV – Booster Upgrade for PETRA IV
Authors: Chao Hung-Chun 
Published: December 2019

Abstract
In PETRA IV project the on-axis injection scheme is preferred since there is no sufficient dynamic aperture for off-axis injection in ultra low emittance storage rings. The challenge is the frequent preparation the injected bunches with the smaller emittance and larger intensity. The current injector complex including the accumulator and booster does not fulfill the requirements and thus will need refurbishments. The injector upgrade option chosen will be composed of an upgraded electron gun, a higher energy LINAC, and the new booster synchrotron DESY IV which has smaller emittance. DESY IV will be located in the existing tunnel of the current booster DESY II. The design of the lattice and some simulation results are addressed in this article.
Radiation damage to undulator electronics at an electron accelerator
Authors: Chung Ting-Yi , Chang Cheng-Hsing , Chen Yi-Wei , Chen Ang-Yu , Huang Jui-Che , Jan Jyh-Chyuan 
Published: December 2019

Abstract
Experience gained from commissioning and operation of three elliptical polarization undulators (EPU) at the TPS taught us that undulator driving systems can behave erratically following a beam dump or loss. In this work, we discuss possible harmful radiation sources in a storage ring and analyse the effect of lack of electronic component radiation resistance in the system. According to measurements of spatial radiation distribution at the TPS, we propose solutions and an improved design for Phase-II EPUs.
Preparation of the EBS beam commissioning
Authors: Liuzzo S M , Carmignani N , Franchi A , Perron T , Scheidt K B , Taurel E , Torino L , White S M 
Published: December 2019

Abstract
In 2020 the ESRF storage ring will be upgraded to a Hybrid Multi Bend Achromat (HMBA) lattice. The commissioning of the new ring will require dedicated tools, either updated from the existing ones or newly developed. Most of the software and procedures were tested on the existing storage ring before its decommissioning. In particular we present experiments on first-turn steering and beam accumulation, check of magnet polarity and calibration, and injection tuning. The use of a control-system simulator proved to be crucial for the debugging of the software and the development of the new control system, as far as beam measurements and manipulations are concerned.
Measurements of the momentum compaction factor of the ESRF storage ring
Authors: Carmignani N , De Nolf W , Franchi A , Nash B , Sahle Ch J , Torino L 
Published: December 2019

Abstract
In a storage ring, the momentum compaction factor can be obtained by measuring the variation of the beam energy as a function of the RF frequency. In this paper we present the measurement of the momentum compaction factor from two different methods. With the first, we measure the variation of the undulator spectra for different RF frequencies. With the second, we measure the variation of the hard x-rays flux produced by a dipole for different RF frequencies.
Superconducting undulator coils with period length doubling
Authors: Casalbuoni S , Glamann N , Grau A W , Holubek T , Saez de Jauregui D 
Published: December 2019

Abstract
Only since few years it has been demonstrated experimentally that NbTi based superconducting undulators (SCUs) have a higher peak field on axis for the same gap and period length in operation with electron beam with respect to permanent magnet undulators (even the ones in vacuum and cooled to cryogenic temperatures). Another advantage of NbTi based SCUs with respect to permanent magnet devices is radiation hardness, widely demonstrated for NbTi magnets, which is and will become an increasingly important issue with the small gaps in the newest machines as round beam storage rings and FELs. Moreover, SCU technology allows switching of the period length by changing the current direction in one of separately powered subset of winding packages of the superconducting coils. This feature further broadens the energy range of the emitted photons, required by the different beamlines. To this end a 0.41 m long superconducting undulator coil with switchable period length between 17 mm and 34 mm has been developed. In this contribution we describe the design and report on the quench tests, as well as on the magnetic field measurementsThe first section in your paper.
Incorporation of a MESA linac module into bERLinPro
Authors: Kuske B , Anders W , Jankowiak A , Neumann A , Aulenbacher K , Hug F , Stengler T , Stoll C P 
Published: December 2019

Abstract
bERLinPro is an Energy Recovery Linac (ERL) project, currently being set up at the Helmholtz-Zentrum Berlin fur Materialien und Energie, Berlin, Germany. bERLinPro is designed as - and for - experiments in accelerator physics and as a test bed for novel ERL components. MESA is an ERL project under construction at the Johannes Gutenberg- Universitt, Mainz, Germany. MESA is designed as a user facility to perform experiments in dark matter physics and precision measurements of natural constants. Despite the diverse goals, the main linac, providing the larger part of the particles energy, is fairly compatible. It is planned to test and run the MESA linac module in bERLinPro, prior to its usage in MESA. The goals and benefits of this unique cooperation for both projects are outlined in this paper. The necessary adaptions in bERLinPro, including hardware aspects, the new optics, and the scope of performance are described.
Mode-locked pulse oscillation of a self-resonating enhancement optical cavity
Authors: Hosaka Y , Honda Y , Omori T , Urakawa J , Kosuge A , Sakaue K , Takahashi T , Uesugi Y , Washio M 
Published: December 2019

Abstract
A power enhancement optical cavity is a compelling means of realizing a pulsed laser with a high peak power and high repetition frequency, which is not feasible using a simple amplifier scheme. However, a precise feedback system is necessary for maintaining the narrow resonance condition of the optical cavity; this has become a major technical issue in developing such cavities. We have developed a new approach that does not require any active feedback system, by placing the cavity in the outer loop of a laser amplifier. We report on the first demonstration of a mode-locked pulse oscillation using the new system.
Error study and correction of Hefei Advanced Light Source
Authors: Xu Derong , Bai Zhenghe , Li Wei 
Published: December 2019

Abstract
Hefei Advanced Light Source (HALS) is a future diffraction limited storage ring. The machine performance under all kinds of magnet errors is a vital component in physical design. In this paper, we present our work on the closed orbit correction, the linear beam optics compensation and the coupling control in HALS. After correction, the dynamical aperture can suffice the injection scheme.
Comparison of optimization methods for hybrid seven-bend-achromat lattice design
Authors: Yang P H , Bai Z H , Xu J H , Tan J J , Wang L 
Published: December 2019

Abstract
Generally, for a hybrid multi-bend-achromat (MBA) lattice with fixed linear optics, there is little potential to further optimize the nonlinear dynamics due to limited free knobs. To obtain a hybrid MBA lattice with better nonlinear dynamics performance, it is better to consider some indicators of nonlinear dynamics as objective functions in designing the linear optics using an optimization algorithm. In this paper, integral strengths of sextupoles and natural chromaticities are used as the nonlinear dynamics indicators, and different optimization methods with both or either of the two indicators are carried out and compared. As an example, a hybrid 7BA lattice with an energy of 2.4 GeV is designed towards an emittance of less than 70 pm-rad.
Multi-Bend Achromat Lattice Design for the Future of TPS Upgrade
Authors: Chiu M S , Huang J C , Chou P J , Lee S Y 
Published: December 2019

Abstract
We present a TPS upgrade option with the hybrid 7BA (H7BA) lattice. We also derive a simple formula on optimal dipole angle distribution among H7BA dipoles. The agreement is satisfactory. We also report preliminary results on the dynamic aperture (DA) optimization. Possible improvement on H7BA lattice is outlined.
Optimization and Measurements on the Double Mini-Betay Lattice in the TPS Storage Ring
Authors: Chiu M S , Chen C H , Liu Y C , Tseng F H , Kuo C C , Tsai H J , Chen J Y , Hu K H , Chiu P C , Liao C Y , Cheng Y S , Lee T Y , Lin W Y , Chen B Y , Hsu T W , Huang B Y , Huang J C , Chou P J 
Published: December 2019

Abstract
The Taiwan Photon Source (TPS) is capable of operating in multi-bunch and single-bunch mode. To operate in a hybrid mode as requested by users, we developed a lattice with chromaticities of 0.8/2 (ξx/ξy) to provide higher single bunch currents. Beam dynamics simulations and lattice characterizations including dynamic aperture, frequency map analysis, tune shift with energy, tune shift with amplitude, and betatron coupling will be discussed in this report.
Undulator Radiation Dose Caused by Synchrotron Radiation at the European XFEL
Authors: Liu S , Li Y , Wolff-Fabris F 
Published: December 2019

Abstract
Radiation damage of the undulators is a big concern for the light sources. At the European XFEL (EuXFEL), dosimeters based on on-line Radfets are used for the undulator radiation dose measurements. However, since the Radfets are not only sensitive to the electrons and neutrons but also to the photons, it can capture the synchrotron radiation (SR) generated in the undulators, which is not considered to be the main source for undulator radiation damage. Therefore, it is important to estimate the contribution of synchrotron radiation to the radiation doses measured by the Radfets. For this purpose, we have first calculated the synchrotron radiation profile using SPECTRA, and then put the profile into the tracking code BDSIM to track it through the whole undulator beam line. The radiation doses from SR have been simulated and compared with the measured values. The differences in the radiation doses measured by the Radfets before and after Pb shielding will also be presented.
Simulation of Short-Pulse Generation from A Dynamically Detuned IR-FEL Oscillator and Pulse Stacking at An External Cavity
Authors: Sumitomo Yoske , Hajima Ryoichi , Hayakawa Yasushi , Sakai Takeshi 
Published: December 2019

Abstract
At the LEBRA facility of Nihon U., we have an IR-FEL oscillator to generate radiations in the range of wavelengths 1 – 6 um for various experiments. A research program has been established to explore the application of the IR-FEL to generate attosecond UV and X-ray pulses through the high harmonic generation (HHG), where the IR-FEL pulses must have a high-peak power and a short-pulse duration. For the suitable FEL pulse generation within a limited macro-pulse length at the LEBRA LINAC, we apply a dynamical modulation to the electron bunch repetition, that is equivalent to a dynamical detuning of the FEL cavity length. We illustrate the potential performance of the IR-FEL with the dynamical detuning by time-dependent 3D FEL simulations. We also evaluate the enhancement of the FEL pulses by an external cavity stacking for the sake of the HHG application.
Stimulated Excitation by Seeding with Cherenkov Radiation in an Optical Cavity
Authors: Jiang S. , Li W. , He Z. , Wang L. , Jia Q. , He D. 
Published: December 2019

Abstract
By seeding with narrow-band Cherenkov radiation from a dielectric loaded waveguide(DLW), stimulated excitation in an optical cavity is presented. The evolution and energy loss of the field oscillating in the optical cavity is analyzed by theoretical and numerical calculation. The results show that the high order TM modes of the Cherenkov radiation can be better preserved after a large number of roundtrips in the optical cavity and this scheme offers a potential method of realizing high power Terahertz radiation source in a compact facility.
Realizing low-emittance lattice solutions with Complex Bends
Authors: Smaluk Victor , Shaftan Timur 
Published: December 2019

Abstract
A concept of new lattice element called “Complex Bend” is recently proposed at NSLS-II. Replacing the regular dipoles in the Double-Bend Achromat lattice by Complex Bends significantly reduces the beam emittance. The first attempt of lattice design for potential NSLS- II upgrade based on Complex Bend, is described. Compared with the current NSLS-II lattice, the new solution modifies only three of the six girders per cell. The linear optics has been matched keeping unchanged the lattice parameters at the straight sections, where the light-generating insertion devices are located. The Complex Bend gradient is limited by 250 T/m assuming possible use of permanent magnets. The lattice provides 65 pm emittance without damping wigglers, use of which results in further decrease of the emittance.
Negative Electron affinity GaAs Cathode Activation with CsKTe Thin Film
Authors: Kuriki Masao , Masaki Kazunari 
Published: December 2019

Abstract
Negative Electron Affinity (NEA) GaAs cathode is an unique device which can generate a highly polarized electron beam with circularly polarized light. The NEA surface is conventionally made by Cs and O/NF3 adsorption on the cleaned p-doped GaAs crystal, but the robustness of the cathode is very limited, so that the electron emission is easily lost by residual gas adsorption, ion back-bombardment, etc. To improve the cathode robustness, NEA activation with a stable thin-film on GaAs surface according to Hetero junction hypothesis has been proposed by the author. An experiment of the NEA activation with CsKTe thin film was carried out at Hiroshima University and a significant electron emission with 1.43 eV photon was observed which strongly suggested NEA activation. The cathode showed 16 to 20 times improvement of lifetime comparing to GaAs activated with Cs and O.
Microwave thermionic electron gun for synchrotron light sources
Authors: Kutsaev S V , Agustsson R , Berry R , Borland M , Chao D , Chimalpopoca O , Nassiri A , Smirnov A Yu , Sun Y , Taletski K , Verma A , Waldschmidt G , Zholents A 
Published: December 2019

Abstract
Thermionic RF guns are the source of electrons used in many practical applications, such as drivers for synchrotron light sources, preferred for their compactness and efficiency. RadiaBeam Systems has developed a new thermionic RF gun for the Advanced Photon Source at Argonne National Laboratory, which would offer substantial improvements in reliable operations with robust interface between the thermionic cathode and the cavity, as well as better RF performance, compared to existing models. This improvement became possible by incorporating new pi-mode electromagnetic design, robust cavity back plate design, and a cooling system that will allow stable operation for up to 1 A of beam current and 100 Hz rep rate at 3.0 μs RF pulse length, and 70 MV/m peak on axis field in the cavity. In this paper we discuss the electromagnetic and engineering design of the cavity and provide the test results of the new gun.
The design and preliminary test of a stripline kicker for HALS
Authors: Liu W , Shang L , Shang F L , Song W B , Sun Z B 
Published: December 2019

Abstract
Stripline kicker is an important component of both on-axis longitudinal accumulation [1] and on-axis swap out injection schemes in HALS (Hefei Advanced Light Source). After more than one year of R&D, construction of the first prototype is completed. The kicker performance is simulated. The results show that in the range of 0 ~ 1 GHz, on differential mode, S11 is less than - 20 dB. In order to facilitate installation, the extension part and PTEF bracket were designed. The assembly of kicker and commercial feedthrough has been tested with pulse generator and network analyzer.