bluuebunny/crossref_metadata_2025_split huggingface dataset:
Características clínico epidemiológicas de pacientes con enfermedad crónica en fase terminal admitidos a un departamento de emergencia general
Authors: Amado-Tineo Jose , Vásquez-Alva Rolando , Huari-Pastrana Roberto , Villavicencio-Chávez Christian , Rimache-Inca Liliana , Lizonde-Alejandro Rosa , Oscanoa-Espinoza Teodoro 
Published: June 2020

Introducción. Los pacientes con enfermedad crónica terminal (oncológica y no oncológica) acuden con frecuencia a servicios de urgencias. Objetivos. Identificar enfermedad terminal en pacientes admitidos a emergencia, motivo de ingreso, tratamiento y destino, comparando oncológicos y no oncológicos. Métodos. Estudio observacional en mayores de 18 años admitidos al departamento de emergencia de un hospital terciario. Intrumento: Supportive and Palliative Care Indicators Tool. Análisis estadístico: pruebas de Chi-cuadrado y U Mann-Whitney, considerando significancia p <0,05. Resultados. De 4925 admisiones, 271 (5,5%) cumplieron criterios de enfermedad terminal. Se analizaron 233 pacientes, mediana de edad 77 años [28-99], sexo femenino 59%. Diagnóstico de cáncer 42%, demencia 23%, secuela neurológica 15%, cirrosis hepática 12% y otros 8%. Los motivos de ingreso fueroninfección 48%, dolor no controlado 9% y sangrado 7%. Se usó antibióticos en 48% de pacientes, opioides 12%(morfina y tramadol) y transfusiones en el 9%. El 8,6% recibió soporte vital avanzado (ventilación mecánica 5,6%, inotrópicos 4,7% y hemodiálisis 0,8%). La mediana de estancia en urgencias fue 6 días [1-62]; falleció 27%, salió de alta 32% y 42% fue derivado a otro servicio hospitalario. La estancia en emergencia y el destino fueron similares en oncológicos y no oncológicos (p>0,05), presentándose mayor edad y tiempo de enfermedad en pacientes no oncológicos (p<0,01). Conclusiones: Una de cada 20 admisiones al departamento de emergencia evaluado corresponden a enfermedad crónica en fase terminal (más frecuentes no oncológicas), siendo los motivos de ingreso infecciones, dolor y hemorragia.
COVID-19: De respuesta global a respuesta regional en zoonosis emergentes
Authors: Recuenco Cabrera Sergio 
Published: June 2020

La pandemia de COVID-19 es la materialización de los escenarios teóricos de la globalización rápida de una zoonosis emergente. Para ello era necesario que el agente biológico patogénico tenga la habilidad de transmitirse fácilmente al ser humano, lograr adaptarse rápidamente y que las vías disponibles para su diseminación sean eficaces para mantener un numero reproductivo básico (Ro) suficiente para su perpetuación, y/o diseminación explosiva (1,2). Si bien, suena a un plan sinestro para alguna arma biológica, la ciencia ha demostrado el origen natural del SARS-CoV2, agente etiológico del COVID-19; y una vez más la disrupción de los entornos ecológicos de fauna silvestre han resultado en la exposición depoblación humana a un nuevo virus para el que la humanidad completa es susceptible.
Aplicativo móvil en el trabajo colaborativo: valoración en estudiantes de postgrado de gerencia de servicios de salud
Authors: Quispe Mori Wanda , Gutiérrez Crespo Hugo , Matzumura Kasano Juan P. , Pastor García César 
Published: June 2020

Introducción. La tecnología ofrece un enfoque distinto sobre las habilidades de aprendizaje y las actividades que los estudiantes realizan mediante el uso de herramientas de comunicación como WhatsApp. Objetivo. Describir la valoración del aplicativo móvil WhatsApp para el trabajo colaborativo en estudiantes de postgrado de gerencia de servicios de salud. Métodos. Investigación de enfoque cuantitativo, prospectivo, de corte transversal. Se utilizó el instrumento denominado: Cuestionario para valorar WhatsApp en la regulación del trabajo en grupo; de 59 preguntas y cuatro dimensiones. Resultados. El análisis por dimensiones mostró que las respuestas de baja valoración predominan en todos los casos. El análisis del promedio determinó que los estudiantes del segundo semestre respondieron favorablemente sobre el uso del aplicativo móvil, mientras que los de cuarto semestre respondieron negativamente en todas las dimensiones. En el análisis global, el 32,9% corresponden a la alta valoración y valoración media, mientras 34,2% corresponden a baja valoración. Conclusiones: El uso de WhatsApp se considera de baja valoración con respecto al trabajo colaborativo.
Réplica: Sobre la evaluación del clima organizacional y satisfacción del usuario en el Instituto Nacional de Salud del Niño
Authors: Fernández-Oliva Danitza , Revilla-Velásquez María E. , Mamani-Urrutia Víctor A. 
Published: June 2020

Agradecemos los comentarios al artículo publicado en la revista que dirige. Permítanos primero aclarar algunas dudas y brindar información adicional para facilitar la revisión del artículo. Es necesario indicar que nuestro estudio no tuvo como finalidad correlacionar las variables de clima organizacional -reportado por los trabajadores del Instituto Nacional de Salud del Niño (INSN)- y la satisfacción del usuario externo -reportada por quienes acuden a esta institución especializada de salud-. Para correlacionar estas variables serían necesarios aspectos metodológicos y estadísticos diferentes a los que nos planteamos, como por ejemplo homogenizar la población, considerar variables confusoras y correlacionar pares de datos, entre otros. Consideramos que este tipo de análisis no es recomendable, aunque se ha utilizado en estudios previos.
Evaluation of Quality of Life in Patients with Chronic Leg Wounds: Can Platelet-rich Plasma Therapy Help?
Authors: Rainys Domantas , Čepas Adas , Rimdeika Rytis 
Published: June 2020

Aim. The aim of the study was to evaluate and compare the quality of life (QoL) using platelet-rich plasma gel (PRP) and conventional treatment of chronic leg wounds. Methods. Randomized clinical trial was carried out in Hospital of Lithuanian University of Health Sciences Kaunas Clinics during 2014–2018. Patients (n = 69) included in the study were randomly grouped into 2 groups: 1) PRP, 2) Control. SF-36 questionnaire was used to evaluate QoL, visual analog scale was used to evaluate persistent pain associated with ulcer and wound exudate volume was also evaluated. Statistical analysis were performed with SPSS 23.0 package. Results. Patients in PRP group at the end of the treatment rated their QoL over control group patients (p < 0.05). Wound associated pain (PRP – 1.54; control – 2.85; p = 0.015) and pain associated sleep disturbance (p < 0.001) was lower in PRP group patients. Wound exudate volume was lower in PRP group patients at the end of the treatment (p < 0.05). Conclusion. The treatment with PRP is associated with less wound associated pain, less-common sleep disturbance, reduced wound secretion and improved quality of life compared to conventional treatment.
Linear discriminant analysis based on gas chromatographic measurements for geographical prediction of USA medical domestic cannabis
Authors: Al Bakain Ramia Z. , Al-Degs Yahya S. , Cizdziel James V. , Elsohly Mahmoud A. 
Published: June 2020

AbstractFifty four domestically produced cannabis samples obtained from different USA states were quantitatively assayed by GC–FID to detect 22 active components: 15 terpenoids and 7 cannabinoids. The profiles of the selected compounds were used as inputs for samples grouping to their geographical origins and for building a geographical prediction model using Linear Discriminant Analysis. The proposed sample extraction and chromatographic separation was satisfactory to select 22 active ingredients with a wide analytical range between 5.0 and 1,000 µg/mL. Analysis of GC-profiles by Principle Component Analysis retained three significant variables for grouping job (Δ9-THC, CBN, and CBC) and the modest discrimination of samples based on their geographical origin was reported. PCA was able to separate many samples of Oregon and Vermont while a mixed classification was observed for the rest of samples. By using LDA as a supervised classification method, excellent separation of cannabis samples was attained leading to a classification of new samples not being included in the model. Using two principal components and LDA with GC–FID profiles correctly predict the geographical of 100% Washington cannabis, 86% of both Oregon and Vermont samples, and finally, 71% of Ohio samples.
Coronaviral Infection (COVID-19) in Children (Situation on April 2020)
Authors: Namazova-Baranova Leyla S. 
Published: June 2020

Dear friends, colleagues!Not so much time has passed since my last published review on this topic, bit so many news has appeared that has completely changed our vision of the disease and its treatment! It is interesting in both, medical and philosophical way. From philosophical point of view: 1–2 months of our previous pre-COVID life flew quick as lightning but now it is long period while we are observing this new infection and looking for new ways of management and its control. Then as now we are going to discuss its medical part.
Primary Observational Results on Children Who Have Been Exposed to COVID-19 in Moscow
Authors: Rusinova Dina S. , Nikonov Evgeniy L. , Namazova-Baranova Leyla S. , Glazkova Galina P. , Vishneva Elena A. , Kaytukova Elena V. , Privalova Tatyana E. 
Published: June 2020

Background. The number of people infected with SARS-CoV-2 causing COVID-19 is growing worldwide. It is necessary to study features of prevalence and clinical signs in pediatric population considering the fact that this disease is rather new.The aim of the study is to analyze the features of prevalence and clinical signs of pathologic process of COVID-19 in pediatric patients according to the results of practical experience of primary care medical facility (Children’s City Outpatients Clinic № 133) under the conditions of pandemia.Methods. Pediatricians of Children’s City Outpatient’s Clinic № 133 have examined certain categories of pediatric patients (especially who came from abroad or contacted with infection) for the presence of a new coronaviral infection in February 2020. Doctors have been examining children with catarrhal symptoms and hyperthermia since March 2020. The survey of children in February and March was carried out in accordance with algorithms (uniform for adults and children) approved by the Moscow City Health Department. Later, the survey was carried out in accordance with the guidelines for children prepared by the Ministry of Health of the Russian Federation. The throat and nose swabs on SARS-CoV-2 were performed for all patients on the 1st, 11th and 13th day of the disease.Results. 1,900 children (or 3.1% of total attached pediatric population) have been examined in our outpatient’s clinic with the polymerase chain reaction (PCR) method on the presence of the new coronavirus RNA since the beginning of the COVID-19 pandemic in Russia. The course of disease was analyzed in first 100 patients with the confirmed COVID-19 diagnosis: 58 (58%) boys and 42 (42%) girls. In 81% of cases we revealed the source of infection, in 19% – we did not. The disease was asymptomatic in 11 (11%) children examined after the contact with ill relatives; 89% had mild COVID-19 disease with light catarrhal signs. The most numerous group of patients who had COVID-19 consisted of children over 10 years of age (42%); in 20% of cases it was pupils from 7 to 10 years old. Smell disorders were reported in children over the age of 10 in 50% of all cases.Conclusion. New coronaviral infection COVID-19 in children is taking mild course, without complications, under the «mask» of common viral infection. Thus, it is unknown either those who have undergone COVID-19 asymptomatically remain healthy or they need special rehabilitation. The timely development of clear algorithm with step-by-step instructions for various situations for every health professional is crucial during these difficult times.
Percepciones de la comunidad sobre cooperativas
Authors: Arzadun Paula , Masis-Solano Paul 
Published: June 2020

Introducción: Si bien el estudio de las percepciones de los trabajadores de organizaciones de economía social ha sido ampliamente abordado, no ocurre lo mismo con las percepciones de la sociedad sobre dichas organizaciones. En este sentido, el presente artículo pretende conocer la percepción de la comunidad del cantón de San Carlos, Costa Rica, sobre las empresas cooperativas. Dicho cantón es el de mayor extensión de todo el país, y es considerado el más desarrollado y principal eje socioeconómico del norte de Costa Rica. Además, presenta una elevada concentración relativa de cooperativas, que funcionan en casi todas las actividades económicas.
Metodología: Con un enfoque cuantitativo y un diseño descriptivo, se realizaron 196 encuestas.
Resultados: Se retrata una comunidad que se declara altamente conocedora sobre las empresas cooperativas. En términos de preferencias, se observan brechas entre empresas cooperativas, no cooperativas y sector público según se trate de una perspectiva de consumidor, trabajador, o como ciudadano en general.
Conclusiones: se logró una primera aproximación sobre opiniones de habitantes de San Carlos en una materia escasamente explorada, y que resulta completamente novedoso a nivel nacional. Las macrotendencias muestran que el cooperativismo es capaz de forjar alternativas de futuro frente a los retos actuales.
Orthopedic aspects of functional connective-tissue mobility structures in development and course of intra-articular pathology of knee joint
Authors: Ladeischikov V. M. , Denisov A. S. , Zagorak D. P. 
Published: June 2020

Objective. To reveal the influence of functional mobility of connective-tissue structures on the development and course of intra-articular pathology of the knee joint.
Materials and methods. Patients (n = 279) with intra-articular pathology of the knee joint after the arthroscopic treatment were examined. The state of functional mobility of connective-tissue structures was diagnosed using the express method for dysplastic state of connective tissues in conditions of ambulatory-polyclinic service. Statistical analysis was carried out with Pirson correlation criteria.
Results. The paper is devoted to analysis of the influence of functional connective-tissue structure mobility on the development and course of intra-articular pathology of the knee joint. Subjects with low functional mobility of the connective-tissue structures were established to be more often subjected to chondromalacia of cartilaginous tissue of the femoral medial condyle and injury of the medial meniscus. Such pathology as slipping patella, Goff body hypertrophy and knee joint chondromatosis are typical for subjects with hypermobility of the connective-tissue structures.
Conclusions. High degree of functional mobility of connective-tissue structures significantly contributes to preservation of cartilaginous cover of the femoral medial condyle, even with concomitant pathology of the knee joint available. For men with high functional mobility of connective-tissue structures, the most common diseases are knee joint chondromatosis and Goff body hypertrophy, and for women slipping patella. For women with low functional mobility of connective-tissue structures, the most typical is pathology of the medial meniscus.
Iatrogenia as a cause of postcholecystectomy syndrome
Authors: Sitnikov V. A. , Ibragimova D. R. , Kasimova N. R. , Styazhkina S. N. 
Published: June 2020

Objective. To analyze the most frequent diagnostic, tactical and technical errors of young doctors, leading to postcholecystectomy syndrome.
Materials and methods. The analysis was based on the clinical material of 87 patients from the Surgical Department of Regional Clinical Hospital №1 and City Clinical Hospital №2 of Izhevsk regarding reconstructive and restorative surgeries on the biliary tract for the last 40 years (19782018).
Results. The reasons, causing iatrogenic injuries of the bile ducts during cholecystectomy, are diagnostic, tactical, technical. Diagnostic errors are more often associated with inadequate diagnosis of cholelithiasis and cholecystitis (underestimation of history, complaints, clinical picture of the disease and its complications; failure or impossibility of FGDS; insufficient topical diagnosis while ultrasound investigation of the biliary tract and abdominal organs). Tactical errors in surgeries on the gallbladder include: overly expectant tactics, incorrect choice of surgical approach and method of anesthesia, lack of experience of the surgeon, inadequate revision of the biliary tract during surgery, refusal from surgical cholangiography and external drainage of the choledoch in case of doubtful patency of the bile duct. Technical reasons are specific features of the anatomy of the extrahepatic biliary tract, factors complicating the surgery, violation of surgical technique when performing an operation on the bile duct.
Conclusions. Correct and timely diagnosis of bile diseases as well as qualified technique of surgical intervention will minimize the development of post-cholecystectomy syndrome and other iatrogenic complications.
Features of effect of low-intensity laser irradiation on prokaryotic and eukaryotic cells
Authors: Godovalov A. P. , Yakovlev M. V. , Batog K. A. , Remennikova M. V. , Bykova L. P. , Pastukhov D. M. 
Published: June 2020

Objective. To study the possibility of using LED blue, red, and green radiations of a new apparatus to eliminate prokaryotic cells and maintain human cell viability. Currently, laser technologies are widely used in medical practice. However, there are relatively few studies on the effect of laser radiation with similar parameters on the viability of prokaryotic and eukaryotic cells.
Materials and methods. As a radiation generator, the LFDT-02 diode medical laser of a new type from the Perm Scientific and Production Instrument-Making Company was used. Staphylococcus aureus 66G cultures were irradiated with a different wavelengths laser (exposure time 2 min, power 22 mV). After that, the viability of microorganisms was evaluated by direct seeding on nutrient media. To study the effect of laser radiation on macroorganism cells, fasting samples of buccal epithelium were obtained in 17 practically healthy volunteers aged 2025 years with an intact periodontium and dentition, without somatic pathology. To assess cell viability, a vital dye was used 0.1 % trypan blue solution. The exposure time and power do not differ from those for the studied S. aureus strain. To assess the morphological changes of epithelial cells, preparations were prepared for microscopy, which, after fixation, were stained according to the Romanovsky-Giemsa method.
Results. When evaluating the effect of laser radiation, especially in a clinical setting, it is necessary to take into account its possible effect not only on cells of conditionally pathogenic microorganisms, but also on human cells. In the present study, it was shown that laser radiation with a power of 22 mV allows one to achieve a bacteriostatic effect against S. aureus but it also significantly reduces the viability of buccal epithelial cells, that can be considered, on the one hand, as a side effect of laser radiation and, on the other hand, the removal of dying cells filled with microorganisms, can enhance the effect of ongoing therapy.
Conclusions. Based on the results obtained, it can be concluded that the laser radiation of a diode laser with a wavelength of 405 nm (blue) and 650 nm (red) has a pronounced bacteriostatic effect. However, a significant damaging effect of red radiation on macroorganism cells was found.
Experience and possibilities of video laparoscopy in emergency abdominal surgery
Authors: Turbin M. V. , Cherkasov M. F. , Melikova S. G. , Ustimenko I. V. 
Published: June 2020

Objective. To evaluate the effectiveness and improve treatment outcomes for patients with acute abdominal pathologies using video laparoscopy. Materials and methods. The paper is based upon a ten-year experience of using video laparoscopy in emergency abdominal surgery. Within a decade (2008 2018), 23127 patients had been admitted to the surgical department of City Emergency Hospital in the city of Rostov-on-Don; among them 19748 patients were operated on. Video laparoscopic surgeries for acute appendicitis, acute cholecystitis, acute intestinal obstruction, perforated gastric and duodenal ulcers, and other acute abdominal surgical pathologies were performed in 15124 patients; the share of these interventions was 76.6 % of all cases.
Results. Initially, when laparoscopy was introduced in emergency abdominal surgery, diagnostic laparoscopy was used in more than a half of the performed surgeries, mainly for acute appendicitis and abdominal injuries. Today, video endoscopic surgery is widely used for acute cholecystitis, acute pancreatitis, perforated ulcers, strangulated hernias, torsions of epiploic appendages of the colon and of the greater omentum. An effective use of video laparoscopy for therapeutic purposes allows increasing the number of laparoscopic operations performed in patients with emergency surgical pathology of abdominal organs.
Conclusions. Video laparoscopy in urgent surgery allows establishing a diagnosis in time, performing dynamic video laparoscopy, eliminating concomitant pathology, diagnosing and, in some cases, preventing postoperative complications. Video laparoscopic surgery is easier for patients to tolerate; it reduces the number of complications, the period of staying at the hospital and the rehabilitation period, and opens up new possibilities for helping patients with emergency surgical conditions.
Penambahan Sari Lengkuas Merah (Alpinia purpurata) Dalam Edible Coating Pati Sagu Meranti Terhadap Sifat Kimia, Mikrobiologi dan Kesukaan Buah Tomat (Lycopersicum esculentum Mill)
Authors: Ayu Dewi Fortuna , Efendi Raswen , Johan Vonny Setiaries , Habibah Lutfi 
Published: June 2020

This research aim was to study the application of red galanga juice addition in meranti sago starch edible coating on chemical, microbiology, and hedonic properties of tomatoes during storage. The study used a Completely Randomized Design (CRD) with 5 treatments and 3 replications so that 15 (fifteen) experimental units were obtained. The treatments used were P0 (without addition of red galangal juice), P1 (1% addition of red galangal juice), P2 (3% addition of red galangal juice), P3 (5% addition of red galangal juice), and P4 (7 % addition of red galangal juice) in formulation of sago starch edible coating which applicated on tomatoes during 21 days storage. The data obtained were statistically analyzed using Anova and DNMRT at a 5% level. The results showed that the addition of red galangal juice significantly affected weight loss, total dissolved solids, hardness, total microbes, and hedonic organoleptic assessment of the tomato texture. The addition of red galangal juice in edible coating didn’t significantly affect the organoleptic assessment of the tomato color. The best treatment of this research was P4 which showed on tomatoes after 21 days storage that had 16.38% weight loss, 1.39 °Brix total dissolved solids, 5.83 kg/f hardness, 5.52 log CFU/g total microbes, and overall hedonic assessment of color was 2,70 (somewhat like), and 3.26 texture (somewhat like).
The Weighted Power Lindley Distribution with Applications on the Life Time Data
Authors: Rather Aafaq A. , Özel Gamze 
Published: June 2020

In this paper, we have proposed a new version of power lindley distribution known as weighted power lindley distribution. The different structural properties of the newly model have been studied. The maximum likelihood estimators of the parameters and the Fishers information matrix have been discussed. It also provides more flexibility to analyze complex real data sets. An application of the model to a real data set is analyzed using the new distribution, which shows that the weighted power Lindley distribution can be used quite effectively in analyzing real lifetime data.