bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating Readability and Reliability of Online Information Provided by Pancreas Transplant Centers in the United States
Authors: Villani Vincenzo , Shanmugarajah Kumaran 
Published: December 2024

ABSTRACTBackgroundThe decision of proceeding with a pancreas transplant (PTx) is a complex one, and patient education is important to allow transplant candidates to make an informed and autonomous decision. In this study, we assessed the readability and reliability of online information provided by PTx centers in the United States.MethodsWebsites of PTx centers active between 2022 and 2023 were searched for patient information on pancreas transplantation. Readability was assessed using eight validated formulas. Reliability was assessed using the Journal of the American Medical Association criteria.ResultsOf 117 PTx centers, 57 provided online information material. High‐volume centers were more likely to provide patient information compared to medium‐ and low‐volume centers (76.6%, 45.6%, 34.6%, respectively). Average readability was at the 11th grade and beyond, with no difference among the three groups (11.9, 11.4, 11.4). Reliability was low, with two centers providing information on the material sources. Only one center provided information in a language other than English.ConclusionsReadability of online material on PTx provided by US transplant centers is low, well above the recommended 6th grade‐level. Transplant centers, national societies and patient advocacy groups should collaborate in developing information material that is evidence‐based, easy to read, and available in multiple languages.
University Strategies for Addressing Democratic and Migration Cases
Authors: Ul Hassan Mehboob , Hussain Abid , Rashid Khalid , Nawaz Muhammad Hameed 
Published: December 2024

ABSTRACTThis interdisciplinary research explores the complex interplay between democratic erosion and migration crises, recognising their profound implications for social cohesion. With universities serving as bastions of knowledge and inclusion, their role in addressing these challenges is paramount. By implementing targeted programs and initiatives, universities actively contribute to mitigating the adverse effects of these crises and promoting social cohesion within their campuses and surrounding communities. The research objectives encompass a comprehensive examination of existing strategies and programs implemented by universities worldwide, focusing on identifying successful approaches and practices. Additionally, the study seeks to uncover the underlying challenges and obstacles faced by universities in effectively addressing democratic and migration crises, ranging from institutional constraints to sociopolitical factors. Universities hold significant sway in shaping policy discourse and influencing decision‐making processes at local, national, and international levels. Through rigorous research methodologies, including mixed‐methods approaches involving qualitative case studies and large‐scale surveys, this study aims to provide nuanced insights into the root causes and consequences of democratic erosion and migration crises. Ultimately, this research contributes to advancing scholarly understanding in the fields of democratic governance, human mobility, and social cohesion. By offering actionable insights and innovative solutions, it strives to empower policymakers, practitioners, and affected communities to effectively navigate and address these complex challenges, fostering resilience and harmony in societies worldwide.
Examining Teachers' Classroom Practices in the Context of Computational Thinking Skills: A Q Method Study
Authors: Kılıç Sümeyra Meryem , Yıldırım İbrahim 
Published: December 2024

ABSTRACTThis study aimed to examine teachers' classroom practices in the context of computational thinking skills and to determine their views on computational thinking. In the research process, the Q method was used in which quantitative and qualitative methods were used together. The participants of the research consist of 48 primary school teachers. The socioeconomic level of the environment of the schools where they work, professional seniority and gender variables of the teachers in the participants were collected. It was determined that teachers approached computational thinking skills positively, but they did not fully use the subdimensions of computational thinking skills in their classroom practices. It was determined that abstraction, which is seen as the most important dimension of computational thinking skills in the literature, was not consciously used by teachers in their classroom practices.
BAY 81‐8973 Demonstrates Long‐Term Safety and Efficacy in Children With Severe Haemophilia A: Results From the LEOPOLD Kids Extension Study
Authors: Ljung Rolf , Chan Anthony K. C. , Ahuja Sanjay P. , Mancuso Maria Elisa , Marquez Jose Francisco Cabre , Volk Florian , Blanchette Victor , Kerlin Bryce A. , Trakymiene Sonata Saulyte , Glosli Heidi , Kenet Gili 
Published: December 2024

ABSTRACTObjectivesTo report the long‐term safety and efficacy of BAY 81‐8973 in the LEOPOLD Kids extension phase.MethodsPatients received BAY 81‐8973 (25–50 IU/kg) at least twice weekly. The primary endpoint was safety, assessed in all patients who entered the extension phase (n = 82). Efficacy endpoints were assessed in patients without high‐titre inhibitors/immune tolerance induction (n = 67).ResultsChildren (n = 82) received BAY 81‐8973 for a median of 3.1 years per patient and a median of 405 exposure days per patient. Long‐term BAY 81‐8973 treatment was well tolerated, with no cases of de novo inhibitor development in the extension phase. Annualised bleeding rates (ABRs) within 48 h of prophylaxis were low for all bleeds (median [IQR], 0.7 [0–1.9]; mean, 1.4 [SD, 2.1]) and for joint bleeds (median [IQR], 0 [0–0.7]; mean, 0.5 [SD, 1.1]) (n = 67). Twenty‐one of 67 patients (31.3%) had zero bleeds within 48 h of prophylaxis; the treatment response was ‘good’/‘excellent’ in 87.9% of bleeds, and most bleeds resolved with ≤ 2 BAY 81‐8973 infusions (83.5%).ConclusionLong‐term BAY 81‐8973 treatment is well tolerated and maintains low ABRs for all bleeds and joint bleeds in children with severe haemophilia A.
Trial Registration: ClinicalTrials.gov identifier: NCT01311648
A rare cause of acute kidney injury due to recurrent rhabdomyolysis: Carnitine palmitoyltransferase 2 deficiency
Authors: Ozkan Kurtgoz Pervin , Karakose Suleyman , Guney Ibrahim 
Published: December 2024

AbstractThe most common cause of rhabdomyolysis is trauma. In the presence of rhabdomyolysis attacks triggered by heavy exercise and fever, hereditary causes should be investigated. In our study, a case was presented that developed rhabdomyolysis and acute kidney injury due to carnitine palmitoyltransferase 2 (CPT2) deficiency and then required hemodialysis treatment. We wanted to draw attention to hereditary rhabdomyolysis in this case. A 25‐year‐old male patient was hospitalized with pneumonia and acute kidney injury. On examination, muscle enzymes, creatinine, and potassium levels were high. The patient, who was evaluated as having rhabdomyolysis and acute kidney injury, underwent three sessions of hemodialysis treatment due to the indication for renal replacement therapy. He had a history of rhabdomyolysis and acute kidney injury 5 years ago. The only trigger for both attacks was febrile infection. There was a history of acute kidney injury in two of his siblings in family history. In the gene analysis requested due to suspicion of hereditary causes, homozygous mutation was detected in CPT2 whole gene sequence analysis. Medium‐chain triglycerides, low‐fat diet, and L‐carnitine capsules were given for treatment. Carnitine palmitoyltransferase 2 deficiency is the most common form of muscle fatty acid metabolism disorder. The phenotype of the patients can vary from severe infantile form to milder muscle form characterized by rhabdomyolysis. Cases requiring hemodialysis are very rare, so we wanted to present this case. Detection of hereditary rhabdomyolysis is important for preventing new attacks and preventive treatments.
Real‐world efficacy of radiomics versus clinical predictors for microvascular invasion in patients with hepatocellular carcinoma: Large cohort study
Authors: Kinoshita Shotaro , Nakaura Takeshi , Yoshizumi Tomoharu , Itoh Shinji , Ide Takao , Noshiro Hirokazu , Hamada Takashi , Kuroki Tamotsu , Takami Yuko , Nagano Hiroaki , Nanashima Atsushi , Endo Yuichi , Utsunomiya Tohru , Kajiwara Masatoshi , Miyoshi Atsushi , Sakoda Masahiko , Okamoto Kohji , Beppu Toru , Takatsuki Mitsuhisa , Noritomi Tomoaki , Baba Hideo , Eguchi Susumu 
Published: December 2024

AbstractAimMicrovascular invasion (MVI) affects the prognosis and treatment of hepatocellular carcinoma (HCC); however, its preoperative diagnosis is challenging. Analysis of computed tomography (CT) images using radiomics can detect MVI, but its effectiveness depends on the imaging conditions. We compared the efficacies of radiomics, clinical, and combined models for predicting MVI in HCC using nonstandardized scanning protocols.MethodsThis multicenter study included 533 patients who underwent hepatic resection for HCC. Patients were divided randomly into training (n = 426) and test groups (n = 107). We manually extracted 3D CT features in hepatic arterial, portal venous, and venous phases. The radiomics model was trained by machine learning. A logistic regression model was developed based on clinical information, and a fused model was created integrating clinical information and radiomics prediction score (Rad_Score). We calculated areas under the receiver operating characteristic curves (AUCs) for the radiomics, clinical, and mixed models in the test groups.ResultsThe clinical model incorporated hepatitis B virus surface antigen, tumor diameter, and log‐transformed α‐fetoprotein and des‐gamma‐carboxyprothrombin. The AUCs of the radiomics and clinical models were comparable (p = 0.76). Rad_Score was not an independent significant factor in the fused model (p = 0.40) and its addition did not improve the accuracy of the clinical model alone (p = 0.51).ConclusionsA clinical model is as effective as a CT radiomics model for predicting MVI status in patients with HCC based on real‐world scanning data, and integration of both models does not improve the predictive performance compared with a clinical model alone.
Properties comparison of dielectric ceramic parts manufactured by powder pressing and injection molding
Authors: Chen Z. , Li T. , Liew S. L. , Wang S. , Chen L. 
Published: December 2024

AbstractDual‐phase dielectric ceramic samples of Mg2SiO4/Ba(AlSiO4)2 were fabricated by ceramic injection molding (CIM), and they were systematically compared with the ones fabricated by conventional powder pressing (CP). It was found that by tuning the processing parameters, CIM samples with density, microstructure, grain size, and phase composition comparable with the CP counterparts can be produced. With optimized processing parameters, CIM samples with a relative density of 94.2% were accomplished, along with homogeneous phase distribution and uniform grain size. Meanwhile, satisfactory dielectric properties were also achieved (a dielectric constant of 6.67, a temperature coefficient of −0.94 ppm/°C, and a quality factor of 352,000 GHz). Moreover, a demonstrator with various blind holes and slots was fabricated by the CIM method, which exhibited good geometrical integrity, uniform microstructure, and consistent mechanical properties.
Structure and durability of opal crystallized glass plates
Authors: Brunswic Léa , Angeli Frédéric , Gautron Laurent , Charpentier Thibault , Gin Stephane , Asplanato Pierre , Kaya Huseyin , Kim Seong H. 
Published: December 2024

AbstractAn opal crystallized glass plate, obtained from the addition of fluorine to a soda‐lime base, has been structurally characterized and altered in food contact like conditions. The investigations on the pristine glass evidenced the nature of CaF2, BaF2, and NaF crystalline phases. Overall a continuum of fully vitreous to glass‐ceramic material was noticed with different morphology: the top surface that resembles a soda‐lime glass which was prepared as a slab and the highly crystallized bulk using powder. Powder and slab were altered together at 70°C in acetic acid 4% (v/v) imposing a pH of 2.4 for 231 days to 3 years. The bulk powder alteration was characterized by a predominant hydrolysis mechanism impacting the crystals and the glassy matrix, leaving no remaining altered layer at the surface whereas a 1.25 µm thick alteration layer was observed on the top surface of the plate after 231 days of alteration. The mechanisms for the formation of this altered layer as well as the differences between the powder, representative of the bulk opal crystallized glass, and the slab that remains the actual surface in contact with edibles are discussed in the article.
Inform Me or Make Me Laugh: Influencer Marketing and the Role of Emotional Contagion and Information Value
Authors: Kapoor Payal S. , Maggon Mohita , Gangwani Kishore Kumar 
Published: December 2024

ABSTRACTInfluencers' humorous product usage anecdotes and story‐based informative collaborative content drive customers' emotional and cognitive responses. Accordingly, this study first examines the impact of humorous and informative content on emotional contagion and information value. Second, it examines the mediating role of emotional contagion and information value that shapes customers' brand engagement and purchase intentions. Third, it tests the boundary conditions imposed by product type. A multimethod quantitative approach was used to test the proposed hypotheses. Two online experiments and two exploratory studies in the form of a social media field experiment and a text analysis study were conducted. The results showed that humorous messages induced emotional contagion, while informative messages produced higher information value. Emotional contagion and information value explained the underlying mechanisms affecting customer brand engagement and purchase intentions. We also found that when employed for hedonic products, humorous messages precipitated stronger emotional responses, while for utilitarian products, informative messages led to higher information value. The study findings offer implications for marketers seeking to enhance customer brand engagement through influencer marketing.
Factors Affecting the Use of ChatGPT for Obtaining Shopping Information
Authors: Foroughi Behzad , Iranmanesh Mohammad , Yadegaridehkordi Elaheh , Wen Jun , Ghobakhloo Morteza , Senali Madugoda Gunaratnege , Annamalai Nagaletchimee 
Published: December 2024

ABSTRACTChatGPT transforms the shopping experience by providing responses in human‐like language about products, services, and brands to customers. This study investigated the influential drivers of intention to use ChatGPT to obtain shopping information. We extended the “extended unified theory of acceptance and use of technology” UTAUT2 by incorporating the direct and moderating effects of trust and technology anxiety. To test the model on data from 412 respondents, a hybrid Partial Least Squares—Artificial Neural Network (PLS‐ANN) approach was employed. This approach combines the strengths of PLS for modeling complex variable relationships and ANN for capturing nonlinear dependencies and interactions. PLS analysis identified performance expectancy, effort expectancy, facilitating conditions, hedonic motivation, and trust as significant drivers of ChatGPT usage. The associations between the intention to use ChatGPT and its predictors are negatively moderated by trust and technology anxiety. ANN analysis revealed that trust has the highest effect on the choice to use ChatGPT, followed by facilitating conditions, performance expectancy, hedonic motivation, and effort expectancy. By extending the UTAUT2 framework and applying the PLS‐ANN method, this study advances the theoretical understanding of technology adoption and provides practical insights for marketers and developers of AI‐driven text generators. It emphasizes the importance of building trust and alleviating technology anxiety to promote wider adoption of ChatGPT. The broader significance of this research lies in its contribution to shaping the future of retail and e‐commerce strategies by encouraging a more informed and user‐centric development of AI technologies in the shopping domain.
Clinical outcomes of patients with non‐tuberculous mycobacterial pulmonary disease in Auckland, New Zealand
Authors: Chen Charlotte , Davies Rebecca , Lewis Christopher , Paynter Jennifer , Christmas Timothy , Nisbet Mitzi 
Published: December 2024

AbstractThis review of non‐tuberculous mycobacterial pulmonary disease over an 11‐year period identified 87 patients (74% women, mean age 66 years). Mycobacterium avium complex was isolated in 86% of patients. Antibiotics were commenced in 52% of patients; however, treatment was poorly tolerated with 36% terminating prematurely. Mortality was significant; death occurred in 31% of patients, with no relationship between death and treatment.
Leaf and Crown Cuticular Wax Responses in Annual Bluegrass (Poa annua L.) Plants Exposed to Ice Encasement
Authors: Chalise Devendra Prasad , Merewitz Emily 
Published: December 2024

ABSTRACTThe plant cuticle, the outermost protective layer of most aboveground plant parts, serves as the first line of defence. While its role in various stress responses has been well‐studied, its role in ice encasement stress tolerance is unknown. This research aimed to investigate changes in cuticular wax on the leaves and crowns of annual bluegrass after different ice encasement durations (0, 40, and 60 days) and to analyse the relationships between wax levels, malondialdehyde (MDA) content, electrolyte leakage (EL), and recovery rate. A two‐year controlled environment study was conducted during 2022–2023 and 2023–2024 in East Lansing, MI, USA. Higher wax coverage was observed on leaves (61.89 μg cm−2) compared to crowns (7.64 μg cm−2). On average for leaves and crowns, the highest wax coverage was observed in the 0‐day treatment (41.10 μg cm−2), whereas the least was observed in the 60 days treatment (27.90 μg cm−2). The reduction on wax coverage was primarily due to C26‐hexacosanol. A strong negative correlation existed between wax coverage, malondialdehyde content, and electrolyte leakage, whereas wax coverage and recovery rate were strongly positively correlated, indicating that cuticular waxes may help protect against stress damage. Future research should explore these mechanisms further to develop effective strategies for alleviating winter stress in grass species.
Impact of Vertical Inter‐Implant Distance in Two Adjacent Single‐Unit Posterior Implants: A Retrospective Cohort Study With 1–8 Years of Follow‐Up
Authors: Gao Jiayu , Yang Yang , Yang Xingmei , Tang Xuemei , Qu Yili , Wu Yingying , Xiang Lin , Man Yi 
Published: December 2024

ABSTRACTAimTo investigate the impact of different vertical interimplant distances (VIDs) on the long‐term success of two adjacent single‐unit implants.Materials and MethodsThis retrospective study categorized implants into two groups based on VID: Group 1 (VID < 2 mm) and Group 2 (VID ≥ 2 mm). Further classification was done according to horizontal inter‐implant distance (HID). Statistical models were used to evaluate the primary outcome of implant survival, secondary outcomes of complication‐free survival rates and radiological findings.ResultsWe included 290 patients with 376 two adjacent single‐unit implants. Group 1 included 223 patients with 280 implants, whereas Group 2 comprised 89 patients with 96 implants. The implant survival rates were 93.2% in Group 1 and 96.8% in Group 2 over the 8 years, with no significant association between the groups. Similarly, the overall complication‐free survival rates were 60.6% in Group 1 and 65.6% in Group 2, showing no significant association between the groups. Radiological assessments also showed no notable association between the groups. This trend was consistent in the subgroup analyses based on HID, with no significant differences in implant survival, complication‐free survival rates or radiological outcomes.ConclusionsConsidering the study limitations of an 8‐year post‐prosthetic review period and despite varying VIDs, our findings showed no significant difference in implant survival, complication‐free survival rates or radiological assessments. This underscores the positive prognosis of two adjacent single‐unit implants and contributes to a deeper understanding of the success factors in implantology.
Trial Registration: The study was registered in the Chinese Clinical Trial Registry (ChiCTR2300073215)
Training and Support Needs in Transitional Care From Hospital to Home of the Health Care Professional‐Caregiver‐Stroke Survivor Triad: A Meta‐Synthesis Study
Authors: Bartoli Davide , Lombardi Eleonora , Trotta Francesca , Macripo Sabrina , Pucciarelli Gianluca , Francesco Petrosino 
Published: December 2024

ABSTRACTIntroductionStroke represents the second leading cause of death worldwide after cardiovascular disease and the first cause of disability in adults. Only 25% of stroke survivors fully recover, 75% survive with some form of disability, and half of them lose self‐sufficiency, negatively impacting their quality of life. This study aims to understand the experiences of stroke survivors and caregivers of training needs and support during the transitional care phase from hospital to home; it also investigates the experience of health care professionals (HCPs) of providing support and training to the dyad during this phase.MethodsMeta‐synthesis was conducted following a critical‐interpretative approach. The SPIDER method was used for sample selection, and the PRISMA research question was adopted for article selection. The search for studies on CINAHL, Pubmed, Scopus, ERIC, PsycInfo and OVID was conducted until August 2024.ResultsOf the 1123 articles found, 32 met the inclusion criteria and were included in the meta‐synthesis. Text analysis revealed two main thematic areas: (1) the training need is a new awareness in the transition of care from hospital to home and (2) moulding oneself to new life. The first theme had six subthemes: need for information and training, uncertainty, involvement, evaluation of training needs, individual discharge planning and physical‐psychological problems. The second theme included three subthemes: different role perception, support after discharge and adaptation to change.ConclusionsKnowing the training and support needs in the stroke survivor caregiver dyad guides HCPs to structure tailored discharge plans. Multi‐method and multidisciplinary training and support interventions such as health coaching, weekend passes and early supported discharge are satisfactory outcomes for the triad involved in the transition of care, as continuous feedback on the needs of the new reality at home fortifies the relationship between the dyad and HCPs. A transitional care pathway based on the dynamic needs of the triad can improve the quality of care in the community.