bluuebunny/crossref_metadata_2025_split huggingface dataset:
ESTUDOS DE CASO EM TREINO PARENTAL PARA FAMÍLIAS EM DESCUMPRIMENTO DE CONDICIONALIDADES DO PROGRAMA BOLSA FAMÍLIA
Authors: Kaiser Fabiana Albertim , Gallo Alex Eduardo , Moura Cynthia Borges de 
Published: November 2020

O objetivo deste estudo foi implementar e avaliar um programa de habilidades parentais em famílias em descumprimento de condicionalidades junto ao Programa Bolsa Família, por abandono escolar entre filhos adolescentes e alta incidência de conflito familiar. O delineamento utilizado foi o estudo de caso. Participaram duas famílias, avaliadas por meio do Inventário de Estilos Parentais – IEP na condição pré e pós-intervenção e no follow up de três meses. A intervenção foi realizada no domicílio e consistiu de oito sessões nas quais se discutiu: autocontrole e manejo do estresse; práticas parentais positivas e negativas; análise de contingências; limites e disciplina. Os resultados mostraram que em ambas as famílias houve o acréscimo de repertório comportamental nas mães quanto ao estabelecimento e cumprimento de regras, instalação do diálogo como forma de negociação e resolução de conflitos, do fortalecimento de vínculos através do afeto, das atividades conjuntas e do reforço positivo.
MAGISTER DIXIT: DOCÊNCIA, PESQUISA E EXTENSÃO
Authors: Cá Lourenço Ocuni , Cá Cristina Mandau Ocuni 
Published: November 2020

A teoria desenvolvida por Paulo Freire sobre o processo de ensino-aprendizagem abrange não somente a educação, mas também envolve contexto sociopolítico no ato de educar. A questão relacionada com a teoria de Freire foi objeto de análise com os estudantes do Curso de Ciência da Natureza e Matemática da Universidade da Integração Internacional da Lusofonia Afro-Brasileira (UNILAB) no primeiro trimestre de 2016, visando integrar os estudantes partícipes do Programa de Iniciação à Docência (PIBID-CAPES) e as práticas educativas observadas em sala de aula nos Municípios de Redenção e Acarape no Estado doCeara. Este artigo é o resultado de investigação e problematização com os estudantes do Curso de Ciências da Natureza e Matemática da UNILAB da concepção de Freire sobre os seguintes temas geradores: educação e conscientização, o ato de ensinar, o ato de estudar, prática educativa e a tríade que compõe a universidade: a docência, pesquisa e extensão.
The value of 99mTc-sestamibi single-photon emission computed tomography-computed tomography in the evaluation and risk stratification of renal masses
Authors: Sistani Golmehr , Bjazevic Jennifer , Kassam Zahra , Romsa Jonathan , Pautler Stephen 
Published: November 2020

Introduction: Differentiation of renal cell carcinoma (RCC) from oncocytoma is a common diagnostic dilemma. A few studies have shown that 99mTc-sestamibi (MIBI) imaging has the potential to characterize indeterminate renal masses. This comparative study evaluated the utility of MIBI single-photon emission computed tomography-computed tomography (SPECT-CT) in the assessment and risk stratification of renal masses.
Methods: A total of 29 patients with 31 renal masses who had cross-sectional imaging and MIBI SPECT-CT, were included. Lesions were categorized as either MIBI-positive or -negative on SPECT-CT. Individual lesion density ranged from 22–56 Hounsfield Units (HU) on the non-contrast CT part of SPECT-CT. Quantitative relative MIBI uptake was calculated by measuring tumor to ipsilateral renal parenchymal uptake. The imaging results were correlated with histopathology.
Results: All oncocytic lesions, including seven oncocytomas and one hybrid oncocytic chromophobe tumor (100%), were positive on MIBI. One chromophobe RCC showed low-grade MIBI uptake. The remaining RCC subtypes, including 15 clear-cell, four papillary, two mixed clear-cell and papillary, and one chromophobe were MIBI-negative. The quantitative relative tumor uptake showed statistically significant higher uptake in the low-risk/oncocytic lesions compared to RCCs.
Conclusions: This study demonstrates that MIBI SPECT-CT is valuable in the characterization of indeterminate renal masses. The combination of MIBI uptake on SPECT and lesion density on non-contrast CT can be used for risk stratification of renal masses. This technique may reduce the need for further imaging (multiphasic CT or magnetic resonance imaging), renal mass biopsy, or surgical resection of low-risk renal masses. Subsequently, more patients could be followed with active surveillance.
Out of the Ordinary
Authors: Mikkelsen Henrik Hvenegaard 
Published: November 2020

This article challenges the tendency, both academic and popular, to assign ‘monsters’ the status of the radical Other: of that which we are not. This widespread inclination to understand monsters as agencies breaking into the ordinary ignores what I propose to call the ‘radical sameness’ of monsters: that is, the multiple ways in which monsters appear to embody the features of what people or society could, potentially, become. To develop this argument the article takes its point of departure in ethnographic research carried out among the Bugkalot of Northern Luzon. Exploring the quasi-mythical character known as the mansasadile, I argue that this figure exposes the potential dangers of individuality and current social change; with the growth of paid labour in the farming industry, the possibility is emerging that the young men will detach themselves from their families. The mansasadile shows the situation whereby the monstrous, rather than being the ‘radical other’ that intrudes into the everyday, is the monstrous that erupts out ‘out of the ordinary’.
Improving models of Tax Administration of digital Companies' Income from Commercial Activities on the Territory of the Russian Federation
Authors: Mitin Dmitry Alekseevich 
Published: November 2020

In the article, the author examines the problems of taxation of income of foreign digital companies faced by the tax administrations of the countries of the world, including the Russian Federation. The subject of the study is modern models of income taxation of foreign digital companies operating in Russia and the world.The purpose of the article is to develop new approaches to the tax administration of the income tax of foreign digital companies in the Russian Federation, both for the long term and to ensure the fiscal interests of the country in the near future. Within the framework of the article, the author examines the modern concept of a permanent representative office of a foreign company, and also highlights the reasons why this concept is not applicable to organizations engaged in e-commerce. The author also gives an assessment of the feasibility of introducing a digital tax in Russia. В The scientific novelty of the work is expressed in the concept of the formation of a permanent representative office of a foreign digital company developed by the Author, as well as in proposals for its introduction into the tax system of the Russian Federation. In addition, the author gives recommendations on the introduction of a digital tax in Russia, develops the main elements of the proposed tax, such as: the object of taxation, the tax base, the tax rate, the tax period and tax benefits for this tax. Also, in order to assess the feasibility of introducing a digital tax by the Author in the conditions of limited open analytical data on cross-border e-commerce in Russia, an assessment of the economic effect for the country from the introduction of this tax is given.
A valid and reliable measure of nothing: disentangling the “Gavagai effect” in survey data
Authors: Arias Victor B. , Ponce Fernando P. , Bruggeman Martin , Flores Noelia , Jenaro Cristina 
Published: November 2020

Background
In three recent studies, Maul demonstrated that sets of nonsense items can acquire excellent psychometric properties. Our aim was to find out why responses to nonsense items acquire a well-defined structure and high internal consistency.

Method
We designed two studies. In the first study, 610 participants responded to eight items where the central term (intelligence) was replaced by the term “gavagai”. In the second study, 548 participants responded to seven items whose content was totally invented. We asked the participants if they gave any meaning to “gavagai”, and conducted analyses aimed at uncovering the most suitable structure for modeling responses to meaningless items.

Results
In the first study, 81.3% of the sample gave “gavagai” meaning, while 18.7% showed they had given it no interpretation. The factorial structures of the two groups were very different from each other. In the second study, the factorial model fitted almost perfectly. However, further analysis revealed that the structure of the data was not continuous but categorical with three unordered classes very similar to midpoint, disacquiescent, and random response styles.

Discussion
Apparently good psychometric properties on meaningless scales may be due to (a) respondents actually giving an interpretation to the item and responding according to that interpretation, or (b) a false positive because the statistical fit of the factorial model is not sensitive to cases where the actual structure of the data does not come from a common factor. In conclusion, the problem is not in factor analysis, but in the ability of the researcher to elaborate substantive hypotheses about the structure of the data, to employ analytical procedures congruent with those hypotheses, and to understand that a good fit in factor analysis does not have a univocal interpretation and is not sufficient evidence of either validity nor good psychometric properties.
Effect of Group Work in Addressing the Misconceptions of Light
Authors: Wangchuk Sangay , Penjor Tandin 
Published: November 2020

Physics is science that determines the living and life styles of the people. However, it has many misconceptions in the concepts. In this study, the effect of group work and traditional method in addressing the Class IX student’s misconceptions about light is investigated. The explanatory sequential mixed method was used for the study. It was carried out in one of the Middle Secondary School [MSS] under Trashigang district. The sample of this study consisted of 42 Class IX students and 5 science teachers. The data collection was done using multiple choice questions as pre-test and post-test with explanations. The semi-structured interview was conducted to support the quantitative findings.
The data obtained indicated that the students in the experimental group were more successful in addressing the misconception of light concept than the control group. The independent t-test result showed the significant difference in terms of mean score p<0.05 in the post test result. The result obtained from the study rejects the null hypothesis. The findings confirm that the group work is effective in addressing the misconceptions of light comparing to traditional method of teaching and learning.
The Study of Ethnobotanical Uses by Local Healers in Taktse Chiwog from Central Bhutan
Authors: Penjor Dorji , Tshering Taw , Bhattaria Gangaram , Namgay Tshering 
Published: November 2020

Aim: To document the ethnobotanical uses in Taktse Chiwog (Village blocks) by local healers.
Study Design: Semi-structured interview and direct interview was conducted with the prior approval from the Chiwog official. Two local healers/informants were contacted for interview before field visits based on their popularity and experience of using medicinal plants in their locality.
Place and Duration of Study: The study was conducted at Taktse Chiwog, Trongsa Dzongkhag, Bhutan between July and October 2019.
Methodology: Two local healers were identified based on their experience on ethno medical practice. Multiple approaches were taken such as botanical inventories, collection of plant specimens, semi-structured and direct interviews with local healers including free listing (FL) and preference ranking (PR) to collect the information on medicinal use/s using questionnaires.
Results: Eighty Two plant species from forty nine families were recorded with their ethno medicinal uses by the local healers against various ailments and diseases.
Conclusion: This study suggests that most of the medicinal plants available within locality are commonly used by the healers for the treating different diseases, dislocation and fracture of musculoskeletal system.
Investigating the Modulatory Effect of Methanol Extract of Daniellia oliveri (ROLFE) Leaves on Mitochondrial Membrane Permeability Transition (MPT) Pore
Authors: Achem Jonah , Onyiba Cosmos Ifeanyi , Akinwole Mobolaji T. , Malgwi Jemimah M. , Bolarin Omosola L. , Olorunsogo Olufunso O. 
Published: November 2020

Background: Mitochondrial-mediated cell death begins with opening of mitochondrial membrane permeability transition (mPT) pore and medicinal plants contain phytochemicals that modulate the mPT pore.
Hypothesis and Purpose: We investigated the modulatory effects of crude methanol extract of Daniellia oliveri leaves (CMDO) on mPT pore in vitro.
Study Design and Methods: Phytochemical screening and antioxidant activities of crude methanol extract of Daniellia oliveri leaves (CMDO) were evaluated according to standard procedures. CMDO was partitioned into chloroform fraction (CFDO), ethyl acetate fraction (EFDO) and methanol fraction (MFDO) by Vacuum liquid chromatography (VLC). Effects of CMDO, CFDO, EFDO and MFDO on mPT pore were assessed by spectrophotometry. Effects of the most potent fraction on mitochondrial ATPase, Fe-induced lipid peroxidation and cytochrome c release were assessed by spectrophotometry. CMDO was subjected to GC-MS analysis to identify the bioactive compounds present.
Results: CMDO contains phytochemicals and showed appreciable total flavonoid content (0.483±0.02 QE mg/100g), total phenolic content (0.886±0.12 GAE mg/100g), total antioxidant capacity (0.039±0.001 AE mg/100 g), ferric antioxidant reducing power (IC50=350 µg/ml) and 2, 2-diphenyl-1 picrylhydrazyl (DPPH) radical scavenging activity (IC50=166 µg/ml). The maximum induction of mPT pore opening in the absence and presence of calcium, respectively, were as follows: CMDO (10.11 folds, 5.18 folds), CFDO (19.9 folds, 16.3 folds), EFDO (7.5 folds, 23.2 folds), MFDO (22.2 folds, 31.3 folds). The most potent mPT pore-opening fraction (MFDO) enhanced mitochondrial ATPase activity, inhibited Fe-induced lipid peroxidation and caused cytochrome c release. GC-MS analysis of CMDO revealed the presence of bioactive compounds including methyl propanamide, Dibutyl phthalate, saturated and unsaturated fatty acids.
Conclusion: Methanol fraction (MFDO) of CMDO most potently induced mPT pore opening via enhancement of mitochondrial ATPase activity, which was substantiated by the release of cytochrome c (in vitro). This includes MFDO as a candidate pharmacologic remedy for diseases associated with insufficient apoptosis.
The Effectiveness of the Heated Humidified High Flow Nasal Cannula as an Initial Noninvasive Respiratory Support for Preterm Infants Suffering from Respiratory Distress
Authors: Nofal Sarah Mohamed , Sheikh May Rabie El- , Mahdy Heba Saed El- , Awny Mostafa Mohamed 
Published: November 2020

Aims: to compare the efficacy and safety of the heated humidified high-flow nasal cannula as a noninvasive respiratory support for the initial management of respiratory distress in preterm infants ≥ 30 weeks gestation with birth weight ≥ 1300 g at different flow rates (3 L/min and 6 L/min) on admission.
Study Design: A Randomized controlled trial.
Place and Duration of Study: Neonatal Intensive Care Unit, Pediatrics department, Tanta University Hospitals, over one-year period, from December 2018 to December 2019.
Methodology: 30 preterm neonates, with gestational ages ranged between 30 to 36 weeks and birth weight ≥ 1300 g, were randomized to receive HHHFNC at either flow rate 3 or 6 L\min as an initial respiratory support. Primary outcomes included: the incidence of treatment failure of the HHHFNC at flow 3 L/min and 6 L/min, which will require n CPAP or NIMV, or will require intubation. Secondary outcomes included: rate of deaths at any time after randomization, the total duration of all types of oxygen support and incidence of neonatal morbidities such as nasal trauma, symptomatic patent ductus arteriosus (PDA), intraventricular hemorrhage (IVH ≥ grade II), pneumothorax, pulmonary hemorrhage, retinopathy of prematurity (ROP), apnea, sepsis and necrotizing enterocolitis (NEC ≥ stage II).
Results: the incidence of the need for higher flow rate of HHHFNC (n=11, 36.6%) , the need for n CPAP or NIMV after failure of higher flow rate of HHHFNC (n=11, 36.6%), the need for intubation & MV (n=1, 3.3%), the incidence of nasal trauma (n=7, 23.3%), BPD (n=0) , IVH ≥ II (n=0), NEC ≥II (n=0), pneumothorax (n=0) , the median duration of hospitalization =10 days (7-15), the median duration of all oxygen support = 6.5 days (6-7). The failure rate was 11 out of 30 infants (36.6%), no deaths or pulmonary haemorrhage.
Conclusion: HHHFNC use shows similar rates of efﬁcacy to other forms of noninvasive respiratory support in preterm infants with respiratory distress for initial respiratory support with lesser complications. There were better outcomes with higher gestational age and birth weight at either flow rates 3 or 6 L/min.
Epidemiological Assessment and Challenges of the COVID-19 Pandemic in Nigeria
Authors: Aremu Stephen Olaide , Onifade Emmanuel Olumuyiwa , Fatoke Babatunde , Itodo Samuel Olusegun , Oladipo Oluwatosin , Bademosi Olufisayo , Oleni Temilade Taiwo , Ode Tosin Adebola , Abeleje Ebenezer Oluwasanmi , Folorunso Adebowale Olasehinde 
Published: November 2020

The COVID-19 which belongs to the coronaviridae family has continued to spread in a geometric progression version. The disease that originated from Wuhan, Hubei, China has spread to all the continents of the World except Antarctica continent. As of the 5th of August, 2020 there are over 18 million reported cases of COVID-19 from 214 countries and territories of the world. More than 10 million people have recovered while approximately 696,147 people have died due to COVID-19. This review provides general information on the COVID-19 and gives deep insight into the course of the disease, interventions challenges and possible solutions in Nigeria “the giant of Africa”.
Scientific databases including Science Direct, Pub Med, Elsevier, Scopus, and Nature were explored. Data has also been accessed from case reports, newspaper reports, internet data, World Health Organisation (WHO) reports, Centre of Disease Control (CDCs) and Nigerian Centre of Disease Control (NCDCs) reports. US National Library of Medicine, Clinicaltrials.gov, has been accessed to get information about ongoing clinical trials. The literature survey started in the first week of April, 2020 and was completed in the first week of August, 2020. The clinical symptoms of COVID-19 patients are generally categorized as critical, severe, moderate and mild or even asymptomatic in descending order in terms of severity. Predictions from experts in different parts of the World concerning the possible impact of the disease in Africa have been on the downside which is due to a lot of glaring factors including poor health facilities and services.
Tuning Interfacial Energy Barriers in Heterojunctions for Anti‐Interference Sensing
Authors: Zhao Minggang , Yu Jiatuo , Zhang Xiaomin , Li Zhengming , Ding Yu , Edel Joshua B. , Ma Ye , Li Hui 
Published: November 2020

AbstractAnalytes with similar redox properties are normally difficult to distinguish through classic electrochemical methods. This becomes especially true for the on‐site detection in seawater where the high salinity and complex chemical components can impose severe interference. Hereby introducing numerous nanoscale heterojunctions in the Cu/CuO/reduced graphene oxide (rGO)/polypyrrole (PPy) and Cu/CuO/rGO/chitosan electrochemical sensors, tunable interfacial energy barriers to exponentially regulate the electrochemical signal can be constructed. Importantly, these energy barriers are independent to redox but closely related to the electrostatic interaction from absorbed charged analytes such as Hg2+ and Cu2+. Moreover, the similar sensing principle is also valid for the energy barriers in p‐n junctions as demonstrated in the Ni/NiO/ZnO/PPy sensor. The good anti‐interference properties and ultrahigh sensitivity of this sensing mode offers new opportunities in trace analyte detection in harsh environments such as seawater.
LHRH‐Targeted Redox‐Responsive Crosslinked Micelles Impart Selective Drug Delivery and Effective Chemotherapy in Triple‐Negative Breast Cancer
Authors: Xiao Kai , Liu Qiangqiang , Suby Nell , Xiao Wenwu , Agrawal Rinki , Vu Michael , Zhang Hongyong , Luo Yan , Li Yuanpei , Lam Kit S. 
Published: November 2020

AbstractSystemic chemotherapy is efficacious against triple‐negative breast cancer (TNBC), but it is often associated with serious side effects. Here, a luteinizing hormone‐releasing hormone (LHRH) receptor‐targeted and tumor microenvironment‐responsive nanoparticle system to selectively deliver chemotherapeutic drugs to TNBC cells, is reported. This delivery system (termed “LHRH‐DCMs”) contains poly(ethylene glycol) and dendritic cholic acid as a micellar carrier, reversible intra‐micellar disulfide bond as a redox‐responsive crosslink, and synthetic high‐affinity (D‐Lys)‐LHRH peptide as a targeting moiety. LHRH‐DCMs exhibit high drug loading efficiency, optimal particle size, good colloidal stability, and glutathione‐responsive drug release. As expected, LHRH‐DCMs are more efficiently internalized into human TNBC cells through receptor‐mediated endocytosis, resulting in stronger cytotoxicity against these cancer cells than the non‐targeted counterpart when encapsulated with paclitaxel (PTX). Furthermore, near‐infrared fluorescence and magnetic resonance imaging demonstrate that LHRH‐DCMs facilitate the tumor distribution and penetration of payloads in three different animal models of breast cancer, including cell line‐derived xenograft (CDX), patient‐derived xenograft (PDX), and transgenic mammary carcinoma. Finally, in vivo therapeutic studies show that PTX‐LHRH‐DCMs outperform both the corresponding nontargeted PTX‐DCMs and the current clinical formulation (Taxol) in an orthotopic TNBC model. These results provide new insights into approaches for precise drug delivery of TNBC.
Sustainably Powered, Multifunctional Flexible Feedback Implant by the Bifacial Design and Si Photovoltaics
Authors: Jung Dongwuk , Song Kwangsun , Ju Hunpyo , Park Hyeongoh , Han Jung Hyun , Kim Namyun , Kim Juho , Lee Jongho 
Published: November 2020

AbstractAdvanced design and integration of functioning devices with secured power is of interest for many applications that require complicated, sophisticated, or multifunctional processes in confined environments such as in human bodies. Here, strategies for design and realization are introduced for multifunctional feedback implants with the bifacial design and silicon (Si) photovoltaics in flexible forms. The approaches provide efficient design spaces for flexible Si
photovoltaics facing up for sustainable powering and multiple electronic components for feedback functions facing down for sensing, processing, and stimulating in human bodies. The computational and experimental results including in vivo assessments ensure feasibility of the approaches by demonstrating feedback multifunctions, power‐harvesting in milliwatts, and mechanical compatibility for operations in live tissues. This work should useful for wide range of applications that require sustainable power and advanced multifunctions.