bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atenção básica e saúde pública: por que e para que compreender o papel do agente na sua formação e preparação dos primeiros atendimentos de saúde
Authors: Flor de Lima Wener Maria Santos 
Published: December 2019

Este trabalho aborda a importância do conhecimento sobre saúde pública e atenção básica, que hoje, nos termos de formação dos profissionais desta área, apresenta um quadro bem diversificado com orientações que favorecem ações para indivíduos que necessitam de cuidados em atenções primárias que abrangem a saúde dos indivíduos. Leva-se em conta a identificação de métodos utilizados para avaliação de incidentes na atenção primária a saúde, os tipos, os fatores contribuintes e as soluções para tornar a atenção inicial a saúde mais segura. Tendo como objetivo principal trazer informações a cerca da atenção básica e conhecer a importância deste debate para a formação profissional do agente de saúde. Metodologicamente o estudo foi realizado a partir da pesquisa descritiva exploratória, onde os autores debatem sobre o tema. Os resultados esbaram em teorias neste campo emergencial que é a saúde primária e a responsabilidade do profissional contracenando com críticas e reflexões pertinentes sobre o assunto.
O ESPAÇO DA CIDADE COMO EXPRESSÃO DO ABANDONO NA OBRA DE FRANCISCO ESPINHARA
Authors: Dantas Maia Jordy , De Barros Melo José Eduardo Martins 
Published: December 2019

Neste artigo analisa-se de que forma se constrói o estilo pessimista de Francisco Espinhara no que diz respeito às relações que sua linguagem estabelece com o mundo contemporâneo das cidades. Trata-se aqui de um estudo que pretende investigar o abandono e o espaço como recortes e marcas de uma obra cuja expressão advém da diluição do homem em suas infinitas possibilidades de solidão e isolamento frente à concretude impassível do espaço em que se insere. Acrescente-se a isso que esta obra foi escrita na efervescência do Movimento dos Escritores Independentes de Pernambuco, que em sua produção literária se identifica com o sentimento da urbe em sua intimidade. O trabalho, de cunho bibliográfico, toma como princípios as ideias de autores que trazem a marca do pessimismo e do niilismo enquanto elementos de suporte da linguagem poética do autor, entre eles, Friedrich Wilhelm Nietzsche e Arthur Schopenhauer e o teórico da lírica moderna Hugo Friedrich. Investiga-se de forma o autor se volta para uma obsessão incidente em sua própria existência na busca por algo que possa amparar sua solidão e sua angústia, vinculando-se a temas voltados para a poesia lírica do final do século XIX e início do século XX. Neste sentido, inserem-se o olhar de Mikhail Bakhtin e Gaston Bacherlard, enquanto aportes que sustentam parte das nossas reflexões no que diz respeito às vozes que encontramos no sujeito e suas relações com o espaço com o qual se relaciona.
EXPERIÊNCIAS LABIRÍNTICAS EM A GERAÇÃO DA UTOPIA, DE PEPETELA
Authors: Silva de Oliveira Mariana 
Published: December 2019

Imagem recorrente nas metaficções contemporâneas, o labirinto alegoriza a própria experiência pós-moderna. As características particulares desta estrutura — fragmentação, descontinuidade, multiplicidade e infinitude — e as sensações associadas à experiência labiríntica — desorientação, incerteza, angústia, ambiguidade — mantêm uma relação estreita com o conceito de metaficção. O objetivo deste trabalho é analisar imagens labirínticas presentes no romance A geração da utopia, do escritor angolano Pepetela. Considerando que o labirinto guarda uma ambiguidade intrínseca, representada tanto na estrutura física quanto no campo simbólico, este trabalho também pretende expor uma reflexão sobre a experiência labiríntica como alegoria da metaficção. Serão articuladas teorias sobre metaficção e ficção desenvolvidas por Linda Hutcheon e Vilém Flusser, para discorrer sobre alguns aspectos da literatura metaficcional identificados no romance, como a intertextualidade e a multiplicidade de “verdades”.
Palavras-chave: Labirinto; Literatura Angolana; Metaficção
ADMET properties of novel 5-O-benzoylpinostrobin derivatives
Authors: Pratama Mohammad Rizki Fadhil , Poerwono Hadi , Siswodiharjo Siswandono 
Published: December 2019

Abstract

Background
Prediction of the properties of absorption, distribution, metabolism, excretion, and toxicity (ADMET) from a compound is essential, especially for modified novel compounds. Previous research has successfully designed several modified compounds of 5-O-benzoyl derivatives from pinostrobin, a flavanone that has cytotoxic activity. This study aims to describe the properties of ADMET from the 5-O-benzoylpinostrobin derivative.

Methods
Prediction of the properties of ADMET was carried out using three web servers consisting of SwissADME, pkCSM, and ProTox-II. The observed parameters are divided into ADMET parameters.

Results
In general, absorption parameters indicate that the 5-O-benzoylpinostrobin derivative has lower water solubility than the parent pinostrobin. Distribution parameters show mixed results for distribution through the blood-brain barrier. Metabolism parameters showed different results with generally inhibitory activity shown in CYP2C19, CYP2C9, and CYP3A4. The excretion parameters showed a higher total clearance than pinostrobin except in the trifluoromethyl derivative. The toxicity parameters showed both pinostrobin and the 5-O-benzoylpinostrobin derivatives, including the class IV toxicity category with the lowest LD50 value indicated by the nitro derivative of 1500, with the possible target of the androgen receptor and prostaglandin G/H synthase 1.

Conclusions
Overall, the 5-O-benzoylpinostrobin derivative has the predicted ADMET profile that is relatively similar to pinostrobin, with the most noticeable difference being shown in the absorption parameters where all 5-O-benzoylpinostrobin derivatives have lower water solubility than pinostrobin.
Utilization of 60/70 penetration grade asphalt on ballast structures with the variation of percentage and the number of pouring layers
Authors: Setiawan Dian M. 
Published: December 2019

AbstractRailroad ballast structure layer may experience a decline in mechanical and geometrical performance due to heavy train and environmental loads. In order to improve the quality of ballast structure, the addition of asphalt to ballast layer can be considered as a solution. Therefore, this research utilizes 60/70 penetration grade asphalt for ballast layer binding and stabilization. The objective of this study was to evaluate and analyze the mechanical behavior of clean-ballast and fouled-ballast layers with 2% and 4% penetration grade 60/70 asphalt poured in one (ballast surface layer) and three ballast surface layers. Compressive strength test was performed to analyze the weight of specimen, vertical deformation, and ballast material abrasion. The most prominent finding to emerge from this research was that the use of 60/70 penetration grade asphalt on ballast surface layer is crucial in retaining the load applied by UTM, in order to produce preferable load distribution to the entire ballast structure. It is found that, the higher the 60/70 penetration grade asphalt proportion and the more layers poured with asphalt, the stronger asphalt in reducing ballast abrasion percentage.
The utility of cranial ultrasound as a screening tool for neonatal ECMO
Authors: McCutcheon Kathryn C. , Wise Linda , Lewis Kristopher , Gilbert Bruce , Bhatia Jatinder , Stansfield Brian K. 
Published: December 2019

Abstract

Background
Neurologic complications including hemorrhage, ischemia, and infarction are often identified in neonates undergoing extracorporeal membrane oxygenation (ECMO) and may contribute to the high morbidity observed in ECMO survivors. Screening for intracranial complications is reliant on bedside transcranial ultrasound (CUS) prior to and during ECMO therapy, and advanced imaging [i.e. computed tomography (CT)/magnetic resonance imaging (MRI)] is recommended after completion of ECMO support. The goal of this study is to describe the correlation of intracranial complications identified on CUS during ECMO and MRI after completion of ECMO.

Methods
Fifty-five neonates underwent ECMO support at the Children’s Hospital of Georgia at Augusta University from January 1, 2012 to December 31, 2017. Forty-four (80%) had a brain MRI performed prior to transfer or discharge. Ultrasound studies were reviewed by a single blinded pediatric radiologist and MRIs were reviewed by a single blinded neuro-radiologist.

Results
Of the 44 neonates with post-ECMO MRI, CUS during ECMO identified intracranial lesions in nine neonates, which were all confirmed on post-ECMO MRI. Sixteen subjects (46%) with unremarkable CUS during ECMO had identifiable lesions on post-ECMO MRI, yielding a sensitivity of 36% and a specificity of 100% for CUS in the detection of intracranial lesions. Despite the lack of correlation between CUS and MR, 84.6% of survivors exhibited normal development at 24 months of age.

Conclusion
While necessary for the identification of intracranial lesions during neonatal ECMO, CUS demonstrated low correlation with post-ECMO MRI in the identification of intracranial lesions, which supports Extracorporeal Life Support Organization (ELSO) recommendations.
Modifiable risk factors for spontaneous preterm birth in nulliparous women: a prospective study
Authors: Dagklis Themistoklis , Tsakiridis Ioannis , Mamopoulos Apostolos , Dardavessis Theodore , Athanasiadis Apostolos 
Published: December 2019

Abstract

Background
Spontaneous preterm birth (sPTB) has a detrimental impact on perinatal outcome, as well as on the resources of health systems in high-income countries. Thus, the objective of the current study was to determine the incidence of modifiable risk factors in pregnancy and their impact on the rate of sPTB.

Methods
All nulliparous pregnant women, in singleton pregnancies, with free medical and obstetric history, were eligible to participate in this study. The primary outcome of interest was the incidence of specific modifiable risk factors for sPTB. The correlations between these risk factors and sPTB were also investigated.

Results
Overall, 2027 women were eligible for the study and agreed to participate. The incidence of sPTB was 4.9%; 25.5% (n = 518) of the participants were in extreme maternal age (<20 or >35 years), 34.5% (n = 701) had an abnormal body mass index (BMI) (<18.5 or ≥25 kg/m2), 4.4% (n = 89) reported use of assisted reproductive technology (ART) and 10.9% (n = 220) reported themselves as smokers in pregnancy. In the multivariate analysis, sPTB was significantly correlated with ART conception [odds ratio (OR): 2.494, 95% confidence interval (CI): 1.196–5.199].

Conclusion
Approximately one in 20 primiparous pregnant women in the study had a sPTB. The study population included a high percentage of women of advanced maternal age, with abnormal BMI and smokers, but these characteristics did not affect the incidence of sPTB. On the other hand, conception following ART increased two-fold the risk of sPTB.
Task-Free Functional Language Networks: Reproducibility and Clinical Application
Authors: Battistella Giovanni , Borghesani Valentina , Henry Maya , Shwe Wendy , Lauricella Michael , Miller Zachary , Deleon Jessica , Miller Bruce L. , Dronkers Nina , Brambati Simona M. , Seeley William W. , Mandelli Maria Luisa , Gorno-Tempini Maria Luisa 
Published: December 2019

Intrinsic connectivity networks (ICNs) identified through task-free fMRI (tf-fMRI) offer the opportunity to investigate human brain circuits involved in language processes without requiring participants to perform challenging cognitive tasks. In this study, we assessed the ability of tf-fMRI to isolate reproducible networks critical for specific language functions and often damaged in primary progressive aphasia (PPA). First, we performed whole-brain seed-based correlation analyses on tf-fMRI data to identify ICNs anchored in regions known for articulatory, phonological, and semantic processes in healthy male and female controls (HCs). We then evaluated the reproducibility of these ICNs in an independent cohort of HCs, and recapitulated their functional relevance with apost hocmeta-analysis on task-based fMRI. Last, we investigated whether atrophy in these ICNs could inform the differential diagnosis of nonfluent/agrammatic, semantic, and logopenic PPA variants. The identified ICNs included a dorsal articulatory-phonological network involving inferior frontal and supramarginal regions; a ventral semantic network involving anterior middle temporal and angular gyri; a speech perception network involving superior temporal and sensorimotor regions; and a network between posterior inferior temporal and intraparietal regions likely linking visual, phonological, and attentional processes for written language. These ICNs were highly reproducible across independent groups and revealed areas consistent with those emerging from task-based meta-analysis. By comparing ICNs' spatial distribution in HCs with patients' atrophy patterns, we identified ICNs associated with each PPA variant. Our findings demonstrate the potential use of tf-fMRI to investigate the functional status of language networks in patients for whom activation studies can be methodologically challenging.SIGNIFICANCE STATEMENTWe showed that a single, short, task-free fMRI acquisition is able to identify four reproducible and relatively segregated intrinsic left-dominant networks associated with articulatory, phonological, semantic, and multimodal orthography-to-phonology processes, in HCs. We also showed that these intrinsic networks relate to syndrome-specific atrophy patterns in primary progressive aphasia. Collectively, our results support the application of task-free fMRI in future research to study functionality of language circuits in patients for whom tasked-based activation studies might be methodologically challenging.
L’INFLUENCE DE L’INTERACTION EDUCATIVE DE LA CLASSE X À SMAN 2 MAGELANG SUR L’INTERET D’APPRENDRE LE FRANÇAIS
Authors: Astuti Putri Dwi , Sudarwoto Sudarwoto , Handayani Sri 
Published: December 2019

L’interaction éducative est une interaction entre le professeur et les lycéens dans l’apprentissage. La bonne interaction donne la motivation aux lycéens, alors ils ont l’intérêt à apprendre les matières. L’objectif majeur de cette recherche est de décrire l’influence de l’interaction éducative à l’intérêt à apprendre le français. C’est une recherché corrélationnelle dont les variables sont l’interaction éducative et l’intérêt à apprendre le français. La population est les lycéens de la classe X au SMA N 2 Magelang. J’ai utilisé l’enquête pour collecter les données d’interaction éducative et l’intérêt à apprendre du français. Cette recherche a utilisé la validité construque et pour savoir la réalibilité d’enquête, j’ai utilisé la formule d’Alpha. J’ai utilisé la formule de Product-moment pour analyser les donneés. Le résultat du Product moment est rxy = 0,965, rtable = 0,297. Cela montre qu’il y a une influence de l’interaction éducative à l’intérêt à apprendre le français.
The interaction between teacher and students in the learning process called educative interaction. The good interaction can give the motivation toward students so it will create interest in the learning process. The research problem are the influence of the interaction toward students’ learning interest in French for grade X in SMA N 2 Magelang. The aim of this research is to describe the influence of educative interaction toward students’ learning interest in French for grade X in SMA N 2 Magelang. This research is correlational research. The variable are educative interaction, and students’ learning interest. The population of this research is the students of grade X, SMA N 2 Magelang. Questionnaire were used to collect the data about educative interaction and learning interest of French. This research use construct validity and alpha formula to measure the reliability of the questionnaire. The collective data were analyzed with product moment correlation formula. The result of the product moment is rhitung = 0,965, rtabel = 0,297. It can be concluded that there is an influence of educative interaction toward students’ learning interest in French of grade X SMA N 2 Magelang.
La Capacité des Étudiants du Sixième Semestre Rediger un Texte Argumentatif
Authors: Pranesthi Bening , Sudarwoto Sudarwoto , Handayani Sri 
Published: December 2019

Dans le cours de la Maitrise de la langue Avancée, les étudiants apprennent quatre compétences de langue en utilisant le manuel Le Nouveau Taxi! 3 qui est approprié du niveau de DELF B1. L’un des matériaux dans Le Nouveau Taxi! 3 est l’argumentation pour persuader des gens. Pour cela, Il faut un test pour savoir la capacité des étudiants à écrire un texte argumentatif. L’objectif de cette recherche est de (1) décrire la capacité des étudiants de la 6è semestre à écrire un texte argumentatif. (2) Décrire les erreurs de la redaction de rédiger du texte argumentatif. C’est une recherche descriptive quantitative. Les répondants de cette recherche est les étudiants de la 6è semestre qui apprennent le cours de la Maitrise de la Langue Avancée.Pour collecter les données, on utilise la méthode du test et de la documentation. Cette recherche utilise la validité du contenu et la fiabilité de l'instrument utilise la formule de corrélation Product-moment. Les résultats de l'analyse des données montrent que (1) la capacité des étudiants du sixième semestre à écrire le texte argumentatif est dans la catégorie suffisante parce que la note moyenne note est de 61.26. La meilleure note est de 78.57 et puis le pire est de 42.82. (2) Les pluparts d’erreurs par les etudiants sont le propos et la proposition.
Through the course of Maitrise de la langue Avancée, students learn four language skills using Le Nouveau Taxi ! 3. Writing is an important activity in language skills to illustrate ideas to persuade the other trough writing. One of the materials contained in Le Nouveau Taxi! 3 is argumentation to persuade others. So, It need to take a test to determine the ability of students to write an argumentative text. This study aims to (1) Describe the ability of 6th semester student to write an argumentative text (2) Describe the errors made by students in the French-language of the sixth semester writing argumentative texte based on argumentif writing criteria. The population of this research is sixth-semester students who take course Maitrise de la langue Avancée, the research respondent there are 30 students. The method used to collect the data is the test method and the documentation method. This research uses the validity of the content and the reliability of the instrument used the product-moment correlation formula. The data was analyzed using descriptive percentage analysis. The results of the data analysis shows that (1) the ability to write sixth semester students to write the argumentative text are in the sufficient category because the average mark is 61.26. The highest rating is 78.57 and then the lowest score is 42.82. (2) The most errors are le propos and la proposition.
Techniques of Translating Adele’s 25 Album into Indonesian and The Naturalness Quality
Authors: Hartono Edi , Yuliasri Issy 
Published: December 2019

This research focuses on analyzing the use of translation techniques and the naturalness of the translated lyrics. The objectives of the study were to investigate the translation techniques used to translate song lyrics and to identify the naturalness in translated lyrics of Adele's 25 album songs. This research was done qualitatively. This research applied the translation technique classification proposed by Molina and Albir (2002:509-511) and the naturalness assessment proposed by Nababan (2012). Data analysis was done by comparing the original language and the translated lyrics version to find out the most used of translation techniques. The rater survey was also done by asking 20 respondents to find out the naturalness level of the translated lyrics. The results of the study showed that there were 276 data of the translated lyrics and 11 translation techniques found in this research. Literal translation technique was the most frequent used, followed by Linguistic compression. Some other translation techniques were used moderately such as, Established equivalent, reduction, and discursive creation. The rest techniques were used in low frequency such as modulation, amplification, compensation, linguistic amplification, transposition, and particularization. In terms of naturalness assessed by twenty respondents found that around 61.95% of the data were considered natural translation, 28.80% were less natural and 9.23% were unnatural. The translation techniques with the highest naturalness were Linguistic amplification technique with a percentage 68.18%, particularization was contributing most to less natural translation with percentage 45%, and the transposition technique was contributing most to unnatural translation with percentage 23%. From the data, it can be concluded that the translated lyrics of Adele's 25 album were mostly natural.
Keywords: Song; Lyric; Translation Techniques; Naturalness
Oscar Wilde's Writing Style in "The Happy Prince" in View of Transitivity Analysis
Authors: Sari Monica Intan , Yulianto Henrikus Joko 
Published: December 2019

This study was aimed to discover the types of processes used and how they influence the author’s writing style in Oscar Wilde’s short story entitled “The Happy Prince”. The methodology used in this study was descriptive-qualitative so the analysis was presented in the form of words, phrases, sentences, and utterances. The study focused on discourse analysis employing ideational function approach, which analyzed the short story from the point of view of linguistics especially Transitivity, a theory developed by M. A. K. Halliday. As a result, there were seven types of processes found in the story namely material, mental, behavioral, verbal, relational, existential, and meteorological. The results of the study showed that material process was the most frequently used process (37%) conducted by the author. Yet, the six others were each employed for about 1% - 25%. This indicated that the use of the type of process influenced the writing style of the author in constructing the story where the different process emphasized different portrayal. The use of material process as the most dominant process might reflect the author’s eagerness to do what he cannot do in his real life. However, it was also supported by the author’s previous career and achievement as a journalist, editor, and critic before he wrote the story. Ultimately, the researcher found that Oscar Wilde’s writing style incorporates the vivid descriptions, aesthetic appearance, conversational style, repetitive pattern, simple and clear language.

Keywords: Oscar Wilde; Writing Style; Discourse Analysis; Ideational Meaning; Transitivity