bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ankylosing spinal hyperostosis or forestier disease: difficulty in diagnosing or lack of knowledge?
Authors: Skryabina E. N. , Magdeeva N. A. , Korneva Y. M. 
Published: February 2020

The article demonstrates a clinical case of a disease that occurs mainly in older age groups — ankylosing spinal hyperostosis (AHP) or Forestier disease. The rarity and lack of knowledge of AHP and the associated lack of alertness in relation to this disease makes its diagnostic a difficult task. The disease is more common in older people, which requires differential diagnosis with degenerative changes of the vertebrae. AHP is a low-symptom disease. Clinical symptoms are determined not so much by hyperostosis of the ligaments and tendons by themselves, but by the development of reactive inflammation of these structures during the process of ossification, overloading of still moving segments of the spine adjacent to ankylosed vertebrae. Of particular importance for this disease is the defeat of the anterior longitudinal ligament, the continuity of its ossification for at least four vertebrae (in contrast to trauma, tumors). Important is absence or low severity of ankylosis of the arched joints, sacroiliitis, characteristic of ankylosing spondylitis. The absence or weak severity of degenerative changes in the intervertebral discs detected in osteochondrosis matters. The presence of laboratory and clinical signs of inflammation, damage to other organs and systems is not typical to this pathology. At present time we have no treatment standards for AHP, which also makes the choice of patient management tactics complicated.The insufficient amount of information about this disease makes wider coverage of the pathology necessary in order to improve diagnostic skills, prescribing timely and complete treatment.
Fisher-Evans syndrome. Casereport in physician’s practice
Authors: Yakushev A. A. , Fedorov I. G. , Ilchenko L. Yu. , Shmycova S. S. , Ilin N. V. , Totolyan G. G. , Sirenova I. O. , Nikitin I. G. 
Published: February 2020

The article presents the clinical features and treatment options for autoimmune thrombocytopenic purpura associated with autoimmune hemolytic anemia in the context of Fisher-Evans syndrome. Patient P. was admitted to the emergency department by an ambulance team with a direct diagnosis of acute pancreatitis. Leading clinical syndromes were hemorrhagic and anemic syndromes. A physical examination also revealed a strip-formed hemorrhagic rash in the area of inguinal folds, the anterior surface of the thighs and lower legs. During the differential diagnostic search, the diagnosis of Fisher-Evans syndrome was established. Initial oral and pulse therapy with prednisone was not effective. The patient received platelet transfusions regularly. When eltrombopag was included in therapy, there was an improvement in the patient’s condition, as well as a tendency to increase the level of platelets. On the 35th day, the patient was discharged from the hospital.We examined various clinical variants of thrombocytopenia, I meet in real clinical practice.
Diagnóstico da Situação Atual da Rede de Sistemas Integrados de Gestão (ERP) nas Micro e Pequenas Empresas Brasileiras
Authors: Stumpf Fabio Rios , Cribb André Yves 
Published: February 2020

Focando nas micro e pequenas empresas brasileiras, do ponto de vista do receptor da tecnologia, na adoção de sistemas integrados de gestão, ou como internacionalmente conhecidos os Enterprise Resource Planning (ERP), o presente estudo buscou diagnosticar a situação atual da adoção dos sistemas integrados de gestão (ERP) nas micro e pequenas empresas. Foi caracterizado as micro e pequenas empresas de acordo com o seu faturamento no ano de 2015. Buscou-se entender o processo de adoção de tecnologia como uma visão mais abrangente da implantação desses sistemas. Foi coletada uma amostra estratificada de 411 empresas, realizada no segundo semestre de 2016, com a presença de empresas entrevistadas em todos os 27 estados brasileiros. Os resultados obtidos possibilitaram diagnosticar a situação atual da adoção dos sistemas integrados de gestão (ERP) nas micro e pequenas empresas brasileiras pesquisadas. Foi observado o ponto de vista do receptor da tecnologia.
Uma análise qualitativa da intenção empreendedora e do comportamento empreendedor no período de 2011 a 2015
Authors: Nakao Aldo Nobuyuki , Leite Luiz Eufrásio da Costa , Carneiro da Cunha Julio Araujo 
Published: February 2020

Este trabalho sintetiza a análise de artigos da base científica Web of ScienceTM, que relacionassem os termos "intenção empreendedora" e "comportamento empreendedor". Foram selecionados artigos em inglês e feita uma análise em relação à proximidade semântica de palavras utilizando o software NVIVO. No total, foram obtidos 85 artigos sobre ?intenção empreendedora? e 86 sobre ?comportamento empreendedor?. Após análise qualitativa dos dados, extraiu-se uma estrutura do tipo nuvem que representava em, termos visuais, a quantidade de palavras relacionadas ao tema em estudo. A contribuição deste estudo se volta para oferecer um panorama das publicações sobre a temática abordada com informações devidamente tabuladas. Assim, as características das publicações sobre essa temática podem ser organizadas
Peningkatan Kemampuan Berpikir Kritis Tema Peristiwa dalam Kehidupan Melalui Model Kooperatif Think Pair Share Kelas VA SDN Giwangan
Authors: Ariztasari Isnanda 
Published: February 2020

This research aims at improving the process of learning and improving the critical thinking skill using cooperative learning model type of think pair share at social studies for grade VA student SDN Giwangan. This research was classroom action research which refered to spiral model from Kemmis and Taggart. Data was collected by test and observation. The analize of data used descriptive quantitative. The result shows that cooperative learning type think pair share on social studies can improve the critical thinking skill. This is showed by average scores and mastery learning percentage in pre action, cycle 1, and cycle II. In pre action, average score is 54,81 and mastery learning percentage is 25%. In cycle 1, average score increase to 75,64 and mastery learning percentage increase to 61%. In cycle II, average score increase to 81,61 and mastery learning percentage increase to 77%.
INTEGRASI ALQURAN PADA MATA KULIAH TRIGONOMETRI
Authors: Ahmad Herlina , Febryanti Febryanti , Tasni Nurfaida 
Published: February 2020

Nilai-nilai ideal dalam pendidikan karakter yang paling banyak berperan adalah nilai ajaran agama, ini menjadi dasar penelitian integrasi Alquran pada mata kuliah trigonometri. Penelitian ini bertujuan untuk melihat ada tidaknya pengaruh integrasi Alquran pada mata kuliah trigonometri terhadap hasil belajar mahasiswa. Jenis penelitian ini yaitu mix-method. Penelitian ini dimulai dengan menyusun draf bahan ajar sebanyak 4 bab yang terintegrasi Alquran yaitu surah Al Anbiya ayat 30, Al-Hujurat ayat 13, Adz-Dzariat ayat 56, Al-Baqarah ayat 142-145 dan surah Yunus ayat 87 serta pendekatan phytagoras kesuksesan. Berdasarkan analisis data kualitatif terhadap angket terbuka diperoleh sebagian besar mahasiswa merespon dengan baik penerapan integrasi alquran pada mata kuliah trigonometri, alasannya selain menambah ilmu tentang trigonometri bola, mahasiswa juga memperoleh pengetahuan tambahan tentang nilai-nilai agama islam melalui ayat-ayat alquran. Hal ini ditunjukkan dari peningkatan grade unjuk kerja pada setiap pertemuan. Sedangkan anlisis data kuantitatif terhadap data hasil belajar trigonometri diperoleh nilai rata-rata pretest 45,83 sedangkan nilai rata-rata postest 79,42. Sedangkan untuk uji hipotesis (one sampel t-test) diperoleh sig. 0,000 yang berarti Ho ditolak. Dari hasil analisis disimpulkan bahwa penerapan integrasi Alquran berpengaruh signifikan terhadap hasil belajar trigonometri.
Potensi Kitosan Bersumber dari Limbah Cangkang Rajungan (Portunus pelagicus) dalam Bidang Farmasi
Authors: Husni Patihul , Junaedi Junaedi , Gozali Dolih 
Published: February 2020

Produksi rajungan (Portunus pelagicus) di Indonesia dalam satu tahun mencapai 30.000 ton yang yang menghasilkan sisa buangan limbah cangkang rajungan. Rajungan, memiliki kandungan kitin yang dapat diproses lebih lanjut melalui reaksi deasetilasi menjadi kitosan. Kitosan bersifat biocompatible dan biodegradable. Kitosan dalam bidang farmasi dimanfaatkan sebagai bahan eksipien obat dan belum banyak dimanfaatkan sebagai zat aktif obat. Dengan demikian, limbah cangkang rajungan memiliki potensi yang sangat besar untuk dijadikan produk yang lebih bermanfaat, yaitu berupa kitosan. Kata kunci: rajungan (Portunus pelagicus), kitin, kitosan
Authors: Wahdaniyah Sitti Rabiatul 
Published: February 2020

Keterbukaan akses informasi di era digital memberikan peluang bagi partai politik melalui struktur berjenjang untuk membangun komunikasi politik, berkaitan dengan usaha pencapaian kehidupan demikratis dan peningkatan derajat kualitas kepercayaan masyarakat kepada parpol sebagai salah satu wadah konstitusional. Melalui komunikasi isu dan gagasan politik, parpol berupaya memperoleh sejumlah akumulasi pendapat individual secara terbuka dan membentuk opini publik melalui suatu kegiatan berupa debat pembicaraan, atau pertukaran informasi antara individu yang berada dalam satu kelompok. Dampak komunikasi politik dan opini publik terhadap perilaku masyarakat tidak dapat digeneralisir, karena dampak berbeda yang ditimbulkannya pada setiap individu karena perbedaan latar belakang usia, jenis kelamin, agama, pendidikan, kecerdasan, pekerjaan, kelas sosial-ekonomi, dan sebagainya. Selain itu, publik adalah manusia yang bisa menerima, menolak, mempertanyakan, mengkritisi sehingga dengan begitu banyaknya sumber informasi, publik bisa membandingkan pesan dari satu media dengan pesan dari media yang lain, atau dengan pesan dari public figure atau otoritas yang ia percayai.
Authors: Ahmad Samlan 
Published: February 2020

Akhir-akhir ini maraknya problem perilaku ummat beragama yang memahami agama secara parsial, menjadikan banyaknya terjadi penyimpangan atas nama agama dan keyakinan. Kekasaran dan kebencian terhadap kelompok lain atas nama ajaran agama serta pemahaman agama yang “sesat”, adalah dampak dari penerimaan manusia terhadap ajaran agama tidak disertai dengan pendidikan dan pemahaman ilmu agama yang baik, sehingga dakwah melalui lembaga pendidikan menjadi pilihan untuk membangun pemahaman keIslaman yang komprehensif dan inklusif. Hasil penelitian ini menunjukkan, bahwa (1) Konsep dakwah Alkhairaat mengikuti gaya dakwah Habib Idrus yakni halus dan simpatik, dengan gaya gerak sejumlah ulama yng mengintroduksi gerakan di berbagai wilayah termasuk di nusantara, dengan menggunakan konsep tabsyit lil ummah yang menjadikan pesan-pesan ajaran agama sebagai berita atau kabar gembira untuk Ummat. (2)Bentuk dakwah yang dilakukan oleh Alkhairaat adalah dengan mengembangkan lembaga pendidikan yang berorientasi pada pembentukan pengetahuan, sikap dan perilaku masyarakat yang sesuai dengan tuntunan ajaran agama Islam
Authors: Sofjan Noorwahid 
Published: February 2020

Wacana seputar HAM (human rights talk) tidak dapat dilepaskan dari bahasan filsafat, hukum, maupun politik. Dalam pada itu, untuk membangun sebuah rangkaian pemahaman yang menyeluruh atas HAM dan hubungannya dengan dunia politik dan aksi kemanusiaan, tulisan ini akan memberikan gambaran singkat tentang sejarah HAM. Kemudian ulasan mengenai HAM berdasarkan tiga tingkatan analisa di atas. Pada aspek filosofis, akan diulas mengenai perkembangan ide hak asasi manusia. Dilanjutkan dengan pembahasan legal hukumnya dan hubunganya dengan nilai ideal normatif yang melandasi aksi kemanusiaan. Dan yang terakhir, adalah pembahasan mengenai dinamika politik yang mewarnai isu ham dan aksi kemanusiaan (humanitarian actions).
The SSC15 QTL-Rich Region Mutations Affecting Intramuscular Fat and Production Traits in Pigs
Authors: Piórkowska Katarzyna , Tyra Mirosław , Żukowski Kacper , Ropka-Molik Katarzyna 
Published: February 2020

Abstract
One of the more interesting regions in the pig genome is on chromosome 15 (115,800,000-122,100,000, SSC15, Sus scrofa 11.1) that has high quantitative trait locus (QTL) density associated with fattening, slaughter and meat quality characteristics. The SSC15 region encodes over 80 genes and a few miRNA sequences where potential genetic markers can be found. The goal of the study was to evaluate the effects of SSC15 mutations associated with villin 1 (VIL1), tensin 1 (TNS1), obscurin-like 1 (OBSL1) genes and with one long non-coding RNA (lncRNA) on productive pig traits and to enrich the genetic marker pool in further selection purpose. The potential genetic markers were identified using the targeted enrichment DNA sequencing (TEDNA-seq) of chromosome 15 region. The selected mutations were genotyped by using HRM, PCR and PCRRFLP methods. The association study was performed using the general linear model (GLM) in the sas program that included over 600 pigs of 5 Polish populations. The rs332253419 VIL1 mutation shows a significant effect on intramuscular fat (IMF) content in Duroc population where AA pigs had a 16% higher level than heterozygotes. The IMF content is also affected by the OBSL1 mutation, and the differences between groups are even up to 30%, but it is strongly dependent on breed factor. The OBSL1 mutation also significantly influences the meat yellowness, backfat thickness and pH level. The performed study delivers valuable information that could be highly useful during the development of the high-throughput genotyping method for further selection purposes in pigs. The OBSL1 and VIL1 mutations seem to be the most promising DNA marker showing a high effect on IMF level.
The Applications of Origanum Vulgare and Its Derivatives in Human, Ruminant and Fish Nutrition – A Review
Authors: Alagawany Mahmoud , Abd El-Hack Mohamed E. , Farag Mayada R. , Shaheen Hazem M. , Abdel-Latif Mervat A. , Noreldin Ahmed E. , Khafaga Asmaa F. 
Published: February 2020

Abstract

Origanum vulgare L. is an aromatic enduring herb that belongs to Lamiaceae family. The bioactive constituents of this herb, such as carvacrol and thymol possess several medicinal properties, such as antioxidant, antidiabetic, anti-inflammatory, antimicrobial, antiviral, antiparasitic, anti-neoplastic, and immune modulatory. Moreover, it is considered a standard natural, less toxic, and residue free feed additive, that is successfully used in livestock and fish. Additionally, in human, Origanum vulgare is extensively used with promising health benefits against respiratory, digestive and urinary disorders. This review casts light on description, chemical composition and structure of Origanum vulgare, as well as its therapeutic applications in human and its biological activities in ruminants and fish, data that will be possibly useful for physiologists, nutritionists and veterinarians.
The Potential Effect of Dietary Tannins on Enteric Methane Emission and Ruminant Production, as an Alternative to Antibiotic Feed Additives – A Review
Authors: Nawab Aamir , Li Guanghui , An Lilong , Nawab Yasir , Zhao Yi , Xiao Mei , Tang Shuyan , Sun Chenyu 
Published: February 2020

Abstract
Antibiotic growth promoters in livestock nutrition cause microbial resistance which produces threats to human health. Therefore, tannins have been considered as natural alternative antibiotic feed additives which possess various biological properties including antimicrobial, anti-inflammatory, antioxidant and immunomodulatory. Additionally, these plants also have antiparasitic and anti-bloat characteristics which contribute to inhibit the enteric methane emission in order to improve nutrient digestibility, milk and meat quality, fatty acids composition and ruminant production. Antibiotic growth promoters have been practiced in animals feeding to increase feed intake, growth rate, weight gain as well as reduce metabolic disorders and energy losses in the rumen. In 2006, the European Union banned the usage of antibiotic growth promoters in the feeding of livestock. This antibiotic resistance issue has increased demand to explore the natural feed additives that might be useful for animal production system. Consequently, natural forages have been categorized as potential feed additives in animal production since it improves nutritive value, protein digestibility, increase amino acid absorption and growth rate. But, some plant materials are usually rich in tannins known as anti-nutritional factors. Therefore, the application of tannin-rich plants in ruminant nutrition needs great precaution due to its possible injurious effects (dose dependent) on animal health such as metabolic disorders. Hence, there is need to give attention to the usage of tannins in ruminant nutrition as an alternative to antibiotics feed additives to investigate its effects on enteric methane emissions and ruminants production. In addition, safety and risk associated with tannins feeding have also been briefly discussed.
Associations of CAST, CAPN1 and MSTN Genes Polymorphism with Slaughter Value and Beef Quality – A Review
Authors: Węglarz Andrzej , Balakowska Anna , Kułaj Dominika , Makulska Joanna 
Published: February 2020

Abstract
The slaughter value of cattle and beef quality are influenced by many factors, which can generally be divided into antemortem (breed, sex, age, housing system, diet, pre-slaughter handling) and postmortem (post-slaughter processing, chilling temperature, packaging). Studies of many authors have shown that meat quality traits can be also influenced by the individual genetic background of an animal. Numerous studies have been conducted worldwide to determine the functions of various genes as well as polymorphisms with potential effects on fattening and slaughter value of cattle and on beef quality. This study reviews the most important research done on the associations of polymorphisms in the calpain, calpastatin and myostatin genes with carcass traits and beef quality. Knowledge about the genes and chromosome regions associated with desired meat quality characteristics may prove very helpful when selecting pairs for mating and estimating the breeding value of offspring, mainly because it is difficult to improve meat quality traits based on conventional selection methods due to their low heritability and polygenic regulation. Furthermore, meat quality evaluation is expensive and can only be carried out after slaughter.
Prevalence and Genetic Diversity of C. Jejuni Isolated from Broilers and their Environment Using flaA-RFLP Typing and MLST Analysis
Authors: Lydekaitienė Viktorija Lėgaudaitė , Kudirkienė E. 
Published: February 2020

Abstract

Campylobacter is highly diverse genetically and also undergoes frequent intraspecific recombination. A major source of campylobacteriosis, which is transmitted to humans is found in poultry. The assessment of the genetic diversity among Campylobacter population is critical to our understanding of the epidemiology. The genetic diversity of Campylobacter jejuni isolates in broilers and their environment were investigated by flaA-restriction fragment length polymorphism (RFLP) and multilocus sequence typing (MLST). The study revealed that 92.3% of the examined broiler flocks were contaminated with Campylobacter spp. A total number of 35 different flaA types defined by flaA-RFLP were found in 448 C. jejuni isolates originated from broilers, litter, puddles, zones, anteroom and wild birds. The most dominant flaA type was XXV. MLST defined 20 sequence types (STs) belonging to 10 clonal complexes (CCs). Among all the STs 9 isolates (15%) were consigned to 2 different STs (ST-7413 and ST-4800), which could not be assigned. The most common CCs were ST-21 and ST-179. The ST-21 CC was common in broilers and environment (puddle water and concentric zones) and the ST-179 CC was specific to wild birds, but also was found in puddle water and concentric zones.
The Effect of Diet with Fermented Soybean Meal on Blood Metabolites and Redox Status of Chickens
Authors: Sembratowicz Iwona , Chachaj Robert , Krauze Magdalena , Ognik Katarzyna 
Published: February 2020

Abstract
The aim of the study was to determine whether replacing soybean meal with 3% or 6% fermented soybean meal would positively affect blood metabolites and redox status of broiler chickens. The experiment was carried out on 600 broiler chickens assigned to three experimental groups of 200 chickens each (10 replications of 20 individuals each). In the control group, soybean meal (SBM) was the main source of dietary protein, whereas the remaining groups were fed diets in which soybean meal was partially replaced with 3% or 6% fermented soybean meal (FSBM-3%, FSBM-6%). The fermentation of the SBM contributed to an increase of Lactobacillus, content of crude protein, methionine and lysine, and especially over a 30-fold increase in the concentration of lactic acid. The inclusion of 3% or 6% share of FSBM in the diet of chickens contributed to an increase in total antioxidant potential (FRAP) and plasma total glutathione content. In blood of chickens receiving FSBM an increase of total protein and HDL cholesterol content, aspartate aminotransferase activity and a decrease in urea content were noted. In addition to the positive effect on protein and lipid metabolism as well as antioxidant defence, the diet with a 6% share of FSBM improved body weight gain of chickens. In conclusion, it can be suggested that introducing 6% share of FSBM in place of FSM is more justified.
Effect of Different Levels of Copper Nanoparticles and Copper Sulfate on Morphometric Indices, Antioxidant Status and Mineral Digestibility in the Small Intestine of Turkeys
Authors: Jankowski Jan , Otowski Kamil , Kozłowski Krzysztof , Pietrzak Piotr , Ferenc Karolina , Ognik Katarzyna , Juśkiewicz Jerzy , Sawosz Ewa , Zduńczyk Zenon 
Published: February 2020

Abstract
It was hypothesized that dietary copper (Cu) nanoparticles, as a substitute for the commonly used copper sulfate, could contribute to lowering the dietary inclusion levels of Cu without compromising growth performance or reducing Cu digestibility and utilization in turkeys. An experiment was carried out on 648 one-day-old Hybrid Converter turkeys divided into 6 groups with 6 replicates per group in a two-factorial design with 3 dietary inclusion levels of Cu (20, 10 and 2 mg kg−1) and 2 dietary sources of Cu, copper sulfate and Cu nanoparticles (Cu-SUL and Cu-NPs, respectively). The apparent digestibility coefficients of minerals were determined after 6 weeks, and tissue samples were collected after 14 weeks of experimental feeding. A decrease in the dietary inclusion levels of Cu from 20 to 10 and 2 mg kg−1 did not reduce the body weights of turkeys at 42 and 98 days of age. In comparison with the remaining treatments, the lowest dietary inclusion level of Cu significantly decreased MDA concentrations in small intestinal tissue (P=0.002) and in the bursa of Fabricius (P=0.001). The replacement of Cu-SUL with Cu-NPs differentially modulated the redox status of selected tissues, i.e., enhanced SOD activity in small intestinal tissue (P=0.001) and decreased total glutathione levels in the bursa of Fabricius (P=0.005). In general, neither the different levels nor sources of additional dietary Cu (main factors) exerted negative effects on the histological structure of the duodenum and jejunum in turkeys. The intestinal digestibility of Cu increased with decreasing dietary Cu levels, and as a consequence, the highest apparent digestibility coefficient of Cu (and zinc) was noted in turkeys fed diets with the addition of 2 mg kg−1 Cu-NPs. Therefore, the environmental burden of excreted Cu was substantially reduced along with decreasing dietary Cu levels but it did not depend on the Cu source.