bluuebunny/crossref_metadata_2025_split huggingface dataset:
Typhoon Type Index: A New Index for Understanding the Rain or Wind Characteristics of Typhoons and Its Application to Agricultural Losses and Crop Vulnerability
Authors: Lin Yuan-Chien , Wang Wen-Hsin , Lai Chun-Yeh , Lin Yong-Qing 
Published: April 2020

AbstractHeavy rainfall and strong wind are the two main sources of disasters that are caused by tropical cyclones (TCs), and typhoons with different characteristics may induce different agricultural losses. Traditionally, the classification of typhoon intensity has not considered the amount of rainfall. Here, we propose a novel approach to calculate the typhoon type index (TTI). A positive TTI represents a “wind type” typhoon, where the overall damage in a certain area from TCs is dominated by strong wind. On the other hand, a negative TTI represents a “rain type” typhoon, where the overall damage in a certain area from TCs is dominated by heavy rainfall. From the TTI, the vulnerability of crop losses from different types of typhoons can be compared and explored. For example, Typhoon Kalmaegi (2008) was classified as a rain-type typhoon (TTI = −1.22). The most affected crops were oriental melons and leafy vegetables. On the contrary, Typhoon Soudelor (2015) was classified as a significant wind-type typhoon in most of Taiwan (TTI = 1.83), and the damaged crops were mainly bananas, bamboo shoots, pomelos, and other crops that are easily blown off by strong winds. Through the method that is proposed in this study, we can understand the characteristics of each typhoon that deviate from the general situation and explore the damages that are mainly caused by strong winds or heavy rainfall at different locations. This approach can provide very useful information that is important for the disaster analysis of different agricultural products.
Different Influences of Southeastern Indian Ocean and Western Indian Ocean SST Anomalies on Eastern China Rainfall during the Decaying Summer of the 2015/16 Extreme El Niño
Authors: Chen Jiepeng , Yu Jin-Yi , Wang Xin , Lian Tao 
Published: April 2020

ABSTRACTPrevious studies linked the increase of the middle and low reaches of the Yangtze River (MLRYR) rainfall to tropical Indian Ocean warming during extreme El Niños’ (e.g., 1982/83 and 1997/98 extreme El Niños) decaying summer. This study finds the linkage to be different for the recent 2015/16 extreme El Niño’s decaying summer, during which the above-normal rainfalls over MLRYR and northern China are respectively linked to southeastern Indian Ocean warming and western tropical Indian Ocean cooling in sea surface temperatures (SSTs). The southeastern Indian Ocean warming helps to maintain the El Niño–induced anomalous lower-level anticyclone over the western North Pacific Ocean and southern China, which enhances moisture transport to increase rainfall over MLRYR. The western tropical Indian Ocean cooling first enhances the rainfall over central-northern India through a regional atmospheric circulation, the latent heating of which further excites a midlatitude Asian teleconnection pattern (part of circumglobal teleconnection) that results in an above-normal rainfall over northern China. The western tropical Indian Ocean cooling during the 2015/16 extreme El Niño is contributed by the increased upward latent heat flux anomalies associated with enhanced surface wind speeds, opposite to the earlier two extreme El Niños.
Divergent pathways mediate 5-HT1A receptor agonist effects on close social interaction, grooming and aggressive behaviour in mice: Exploring the involvement of the oxytocin and vasopressin systems
Authors: Tan Oliver , Martin Lewis J , Bowen Michael T 
Published: April 2020

Background: 5-HT1A receptor (5-HT1AR) abnormalities are implicated in aggression, and there has been considerable interest in developing 5-HT1AR agonists for treating aggression. Endogenous oxytocin (OXT) released upon stimulation of 5-HT1ARs in the hypothalamus mediates at least some of the effects of 5-HT1AR agonists on social behaviour. Aims: Given 5-HT1AR, OXT receptor (OXTR) and vasopressin V1a receptor (V1aR) agonists can all reduce aggression, the current study aimed to determine whether the anti-aggressive effects of 5-HT1AR stimulation can also be explained by downstream actions at OXTRs and/or V1aRs in a mouse model of non-territorial, hyper-aggressive behaviour. Methods: Male Swiss mice ( N=80) were socially isolated or group housed for six weeks prior to the start of testing. Testing involved placing two unfamiliar weight- and condition-matched mice together in a neutral context for 10 minutes. Results: Social isolation led to a pronounced increase in aggressive behaviour, which was dose-dependently inhibited by the 5-HT1AR agonist 8-OH-DPAT (0.1, 0.3 and 1 mg/kg intraperitoneally (i.p.)), with accompanying increases in close social contact (huddling) and grooming. The effects of 8-OH-DPAT on aggression, huddling and grooming were blocked by pretreatment with a selective 5-HT1AR antagonist (WAY-100635; 0.1 mg/kg i.p.). The anti-aggressive effects of 8-OH-DPAT were unaffected by an OXTR antagonist (L-368,899; 10 mg/kg i.p.), whereas the effects on huddling and grooming were inhibited. Pretreatment with a V1aR antagonist (SR49059; 20 mg/kg i.p.) had no effect. Conclusions: Our study suggests that stimulation of endogenous oxytocin is involved in the effects of 5-HT1AR activation on close social contact and grooming but not aggression.
Revision hip arthroplasty using a porous tantalum acetabular component
Authors: Miettinen Hannu JA , Miettinen Simo SA , Kettunen Jukka S , Jalkanen Jussi , Kröger Heikki 
Published: April 2020

Introduction: Reconstruction of acetabulum in case of bone defects can be challenging. The aim of this retrospective study was to investigate the 10-year survival of trabecular tantalum metal (TM) acetabulum component in revision hip arthroplasty operations and to evaluate complications. Methods: A total of 100 consecutive acetabulum revision hip arthroplasties (100 patients) were operated on between May 2004 and October 2006 at Kuopio University Hospital. The mean follow-up time was 9.4 years and the median was 11.5 years (SD 4.118; range 0.1–13.4 years). Kaplan-Meier survival analysis was performed to study the survival of patients to re-revision surgery. Intra- and postoperative complications and reasons for re-revision were evaluated. Results: The Kaplan-Meier analysis showed a cumulative proportion of revision hip survivorship of 66% at 13.4 years (SE 0.403, 95% CI, 10.886–12.466) based on the need for further re-revision surgery for any major reason. The Kaplan-Meier survival analysis of time to re-revision surgery due acetabular component loosening showed a cumulative proportion of survivorship of 98.9% at 13.4 years (SE 0.136; 95% CI, 12.998–13.529). There were a total of 41/100 complications and the most common complication was dislocation (24/100). Re-revision for any major reason was performed on 18/100 of the revision arthroplasties. The mean time to re-revision was 4.9 years (SD 5.247; range 0.1–13.2 years). Discussion: The trabecular TM acetabular component gives excellent outcomes regarding stability and fixation to the acetabulum in acetabulum revision hip arthroplasty at a minimum of ten years of follow-up. However, acetabular component malposition and the small head size (28 mm) are risk factors for dislocation.
Comparing image quality of single- and dual-energy computed tomography of the brain
Authors: Dodig Doris , Kovačić Slavica , Matana Kaštelan Zrinka , Žuža Iva , Benić Filip , Slaven Jurković , Miletić Damir , Rumboldt Zoran 
Published: April 2020

Purpose Weighted average dual-energy computed tomography (DE-CT) reconstructions are considered a proxy of standard CT images of the brain, recommended for routine clinical use and used as a reference standard in DE-CT research. However, their image quality has not been assessed, which was the aim of our study. Methods Images from 81 consecutive patients who underwent both non-contrast single-energy (SE)-CT and DE-CT of the brain on the same scanner were retrospectively evaluated. Attenuation values (HU) and SD of grey matter/white matter (GM/WM) pairs, along with SD in the posterior fossa and subcalvarial region were measured. Four readers evaluated image noise, GM/WM contrast, posterior fossa and subcalvarial artefacts, as well as overall image quality. Results Weighted average DE-CT GM and WM HU were significantly lower and noise higher compared to SE-CT (GM HU 36.46 v. 41.82; WM HU 28.18 v. 29.94; GM SD 2.93 v. 2.49; and WM SD 3.16 v. 2.44, all p < 0.0001). After correcting the measured SE-CT noise for 37% higher acquisition dose, DE-CT GM noise became significantly lower (2.93 v. 3.11, p = 0.0121). Measured and dose corrected SE-CT GM/WM contrast-to-noise ratio was superior to weighted average DE-CT (3.42 and 2.74 v. 1.95, both p < 0.0001). Weighted average DE-CT had significantly less artifacts on qualitative analysis. Conclusion Weighted average DE-CT images of the brain yield less artefacts at 37% dose reduction and lower noise at SE-CT equivalent dose. Dose-adjusted GM/WM contrast-to-noise ratio of weighted average DE-CT with 0.4 weighting factor remains inferior to SE-CT images.
Platelet-Rich Plasma Augmentation to Microfracture Provides a Limited Benefit for the Treatment of Cartilage Lesions: A Meta-analysis
Authors: Boffa Angelo , Previtali Davide , Altamura Sante Alessandro , Zaffagnini Stefano , Candrian Christian , Filardo Giuseppe 
Published: April 2020

Background: Microfracture is the most common first-line option for the treatment of small chondral lesions, although increasing evidence shows that the clinical benefit of microfracture decreases over time. Platelet-rich plasma (PRP) has been suggested as an effective biological augmentation to improve clinical outcomes after microfracture. Purpose: To evaluate the clinical evidence regarding the application of PRP, documenting safety and efficacy of this augmentation technique to improve microfracture for the treatment of cartilage lesions. Study Design: Systematic review; Level of evidence, 3. Methods: A systematic review was performed in PubMed, EBSCOhost database, and the Cochrane Library to identify comparative studies evaluating the clinical efficacy of PRP augmentation to microfracture. A meta-analysis was performed on articles that reported results for visual analog scale (VAS) for pain, International Knee Documentation Committee (IKDC), and American Orthopaedic Foot and Ankle Society (AOFAS) scores. Risk of bias was documented through use of the Cochrane Collaboration Risk of Bias 2.0 and Risk of Bias in Non-randomized Studies of Interventions assessment tools. The quality assessment was performed according to the Grading of Recommendations Assessment, Development and Evaluation guidelines. Results: A total of 7 studies met the inclusion criteria and were included in the meta-analysis: 4 randomized controlled trials, 2 prospective comparative studies, and 1 retrospective comparative study, for a total of 234 patients. Of the 7 studies included, 4 studies evaluated the effects of PRP treatment in the knee, and 3 studies evaluated effects in the ankle. The analysis of all scores showed a difference favoring PRP treatment in knees (VAS, P = .002 and P < .001 at 12 and 24 months, respectively; IKDC, P < .001 at both follow-up points) and ankles (both VAS and AOFAS, P < .001 at 12 months). The improvement offered by PRP did not reach the minimal clinically important difference (MCID). Conclusion: PRP provided an improvement to microfracture in knees and ankles at short-term follow-up. However, this improvement did not reach the MCID, and thus it was not clinically perceivable by the patients. Moreover, the overall low evidence and the paucity of high-level studies indicate further research is needed to confirm the potential of PRP augmentation to microfracture for the treatment of cartilage lesions.
Tracheostomy Considerations during the COVID‐19 Pandemic
Authors: Shiba Travis , Ghazizadeh Shabnam , Chhetri Dinesh , St. John Maie , Long Jennifer 
Published: April 2020

ObjectiveTo compile current best practices regarding tracheostomy decision making, care, and technical performance during the global COVID‐19 pandemic.Data SourcesArticles listed in PubMed and Google sources for up‐to‐date information.Review MethodsAll sources presenting objective evidence related to the topic were reviewed and distilled.ConclusionsTracheostomy in patients with coronavirus disease should be a rare event yet one that requires significant decision making and procedural deliberation. Indications for surgery must be balanced by risk of disease transmission to health care workers. Considerations are given to personal protective equipment, viral testing, and alternatives.Implications for PracticeOtolaryngologists worldwide must be aware of these considerations to provide safe patient care without undue risk to themselves or their hospital coworkers.
Vitamin D deficiency predicts for poor overall survival in white but not African American patients with multiple myeloma
Authors: Yellapragada Sarvari V. , Fillmore Nathanael R. , Frolov Anna , Zhou Yang , Dev Pallavi , Yameen Hassan , Ifeorah Chizoba , Do Nhan V. , Brophy Mary T. , Munshi Nikhil C. 
Published: April 2020

Key Points
Vitamin D deficiency is a predictor for poor overall survival in patients with multiple myeloma, even after adjusting for age and stage. This difference is only observed in white patients, not African Americans, even under a lower threshold for deficiency.
Learning curve of laparoscopic nephrectomy: a prospective pilot study
Authors: Masoud Mohamed , Ibrahim Ahmed , Elemam Abdelbaset , Elatreisy Adel , Noureldin Yasser , Aubé Mélanie , Fahmy Nader 
Published: April 2020

Abstract
Background
Learning curve of laparoscopic nephrectomy (LN) is mainly affected by two main factors: plotting performance and experience. However, there is paucity in the literature addressing the number of cases required to adopt LN. Herein, we aimed to assess the learning curve of LN for various renal disorders and number of cases required to adopt the technique. Between September 2015 and December 2017, consecutive patients undergoing LN for various renal diseases were enrolled in this study. Patients were divided into two groups, the first 20 cases (group A) and subsequent 20 cases (group B). All procedures were performed by a single trainee urologist under supervision of an expert endourologist. Learning curve was assessed using operative time and incidence of complications.

Results
A total of 40 patients were included in this pilot clinical study. Mean age was 38.2 ± 16.3 years. The mean operative time for patients in group B was significantly lower than the mean operative time for patients in group A (108.5 vs. 139.3 min, p < 0.05). However, there were no significant differences between both groups in terms of intraoperative blood loss (86 vs. 104 ml; p = 0.081), conversion to open surgery (5% vs. 10%; p = 0.256) and postoperative complications (5% vs. 15%; p = 0.09) for group B and group A, respectively. Similarly, there was no significant difference between both groups in terms of hospital stay (42 ± 8 vs. 46 ± 11 h p = 0.01). The trainee surgeon reached a plateau after 22 cases.

Conclusions
Our study suggests that a minimum of 22 LN procedures are needed in order to adopt the technique of laparoscopic nephrectomy. Learning curve of LN is mainly affected by number of performed procedures within a short period of time.
Phylogeography and genetic diversity of the copepod family Cyclopidae (Crustacea: Cyclopoida) from freshwater ecosystems of Southeast Nigeria
Authors: Ni Yijun , Ebido Chike Chukwuenyem , Odii Elijah Chibueze , Wang Jinhui , Orakwelu Chinemerem Hodges , Abonyi Francis Chukwuemeka , Ngene Chinedu Innocent , Okoro Joseph Onyekwere , Ubachukwu Patience Obiageli , Hu Wei , Yin Mingbo 
Published: April 2020

AbstractBackgroundCopepods are key components of aquatic ecosystems and can help regulate the global carbon cycle. Much attention has been paid to the species diversity of copepods worldwide, but the phylogeography and genetic diversity of copepods in Nigeria is unexplored.ResultsUsing a mitochondrial cytochromecoxidase subunit I marker, we preformed phylogenetic and phylogeographic analyses for Cyclopidae copepods in Southeast Nigeria. A high species diversity of Cyclopidae in Nigeria: 5 species ofTropocyclops, 5 species ofMesocyclopsand 2 species ofThermocyclopsfrom Cyclopidae were identified in 15 populations. Moreover, we detected 18 unique haplotypes, which fell into two distinct clades. Pairwise genetic distances (uncorrectedp-distances) among the species of Cyclopidae ranged from 0.05 to 0.257. Several species co-existed in the same lake, and some haplotypes were shared among different geographic populations, suggesting a dispersal of Cyclopidae in our sampling region. Finally, we found that the population genetic diversity for each species of Cyclopidae was low in Nigeria.ConclusionsOur findings explored the species diversity and distribution of copepods within the family Cyclopidae for 15 Nigerian freshwater ecosystems: a high species diversity of Cyclopidae copepods was detected over a small geographic sampling range. Results from this study contribute to a better understanding of copepod diversity of Nigerian freshwater ecosystems.
Prevalence and associated factors of undiagnosed atrial fibrillation among end-stage renal disease patients on maintenance haemodialysis: a cross-sectional study
Authors: AlAwwa Izzat , Al-Hindi Reham , Alfraihat Nadeen , Obeid Ahmad , Ibrahim Sarah , Jallad Shatha , Al-Awwa Ahmad , Saleh Akram 
Published: April 2020

Abstract
Background
Atrial fibrillation (AF) is the most prevalent sustained arrhythmia worldwide and it aggravates cardiovascular morbidity and mortality; however, this is largely under-diagnosed. Moreover, among end-stage renal disease patients on haemodialysis, AF is substantially more common and serious. The researchers conducted this study to assess the prevalence of, and the factors correlated with AF in Jordanian haemodialysis patients.

Methods
In a cross-sectional analysis conducted from October 2018 to February 2019 in four tertiary hospitals, the researchers enrolled all consenting patients aged 18 years or older who were on haemodialysis for at least three months prior to the study. We screened for AF clinically by pulse palpation, precordial auscultation, by an automated blood pressure monitor and an electrocardiogram. The researchers reported qualitative variables as counts and frequencies, while continuous variables were summarised using the mean or median where necessary. We used multiple logistic regression with backward selection to identify independent risk factors of AF.

Results
A total of 231 patients were enrolled; mean age was 54.8 ± 15.6 years (from 20 to 86), and 44.3% of them were women. The prevalence of AF was found to be 7.8% (95% CI, 4.8–12.2), with no gender disparity. Age (adjusted odds ratio [AOR] = 1.05; 95% CI, 1.01–1.10; p = 0.031), history of ischaemic heart disease (AOR = 3.74; 95% CI, 1.09–12.34; p = 0.033), history of smoking (AOR = 0.15; 95% CI, 0.02–0.60; p = 0.019), and low interdialytic weight gain (AOR = 0.50: 95% CI, 0.25–0.91; p = 0.031) were independently correlated to AF.

Conclusions
The prevalence of AF among patients on maintenance haemodialysis is high, but largely undiagnosed. AF is generally associated with advancing age, history of ischaemic heart disease, lower interdialytic weight gain, and history of smoking. We suggest routine check-up of AF in this high-risk group of patients as anticoagulant therapy if indicated may prevent serious complications. However, there is a need for large-scale cohort studies and for the creation of regional chronic kidney disease and dialysis registries in the Middle East region.
A needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest in Norway
Authors: Brede Jostein Rødseth , Kramer-Johansen Jo , Rehn Marius 
Published: April 2020

AbstractIntroductionOut of hospital cardiac arrest (OHCA) carries an 86% mortality rate in Norway. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potential adjunct in management of non-traumatic cardiac arrest and is feasible in pre-hospital setting without compromising standard cardiopulmonary resuscitation (CPR). However, number of patients potentially eligible for REBOA remain unknown. In preparation for a clinical trial to investigate any benefit of pre-hospital REBOA, we sought to assess the need for REBOA in Norway as an adjunct treatment in OHCA.MethodsRetrospective observational cohort study of data from the Norwegian Cardiac Arrest Registry in the 3-year period 2016–2018. We identified number of patients potentially eligible for pre-hospital REBOA during CPR, defined by suspected non-traumatic origin, age 18–75 years, witnessed arrest, ambulance response time less than 15 min, treated by ambulance personnel and resuscitation effort over 30 min.ResultsIn the 3-year period, ambulance personnel resuscitated 8339 cases. Of these, a group of 720 patients (8.6%) were eligible for REBOA. Only 18% in this group achieved return of spontaneous circulation and 7% survived for 30 days or more.ConclusionThis national registry data analysis constitutes a needs assessment of REBOA in OHCA. We found that each year approximately 240 patients, or nearly 9% of ambulance treated OHCA, in Norway is potentially eligible for pre-hospital REBOA as an adjunct treatment to standard resuscitation. This needs assessment suggests that there is sufficient patient population in Norway to study REBOA as an adjunct treatment in OHCA.
Increased recurrent risk did not improve cerebrovascular disease survivors’ response to stroke in China: a cross-sectional, community-based study
Authors:   on behalf of the FAST-RIGHT Investigators and Coordinators, Li Shengde , Cui Li-Ying , Anderson Craig , Gao Chunpeng , Yu Chengdong , Shan Guangliang , Wang Longde , Peng Bin 
Published: April 2020

Abstract
Background
Cerebrovascular disease (CVD) survivors are at a high risk of recurrent stroke. Although it is thought that survivors with higher risk of stroke respond better to stroke onset, to date, no study has been able to demonstrate that. Thus, we investigated whether the intent to call emergency medical services (EMS) increased with recurrent stroke risk among CVD survivors.

Methods
A cross-sectional community-based survey was conducted from January 2017 to May 2017, including 187,723 adults (age ≥ 40 years) across 69 administrative areas in China. A CVD survivor population of 6290 was analyzed. According to the stroke risk score based on Essen Stroke Risk Score, CVD survivors were divided into three subgroups: low (0), middle (1–3) and high (4–7) recurrent risk groups. Multivariable logistic regression models were used to identify the association between the stroke risk and stroke recognition, as well as stroke risk and EMS calling.

Results
The estimated stroke recognition rate in CVD survivors with low, middle, and high risk was 89.0% (503/565), 85.2% (3841/4509), and 82.5% (1001/1213), respectively, while the rate of calling EMS was 66.7% (377/565), 64.3% (2897/4509), and 69.3% (840/1213), respectively. The CVD survivors’ knowledge of recognizing stroke and intent to call EMS did not improve with recurrent stroke risk, even after adjustment for multiple socio-demographic factors.

Conclusions
Despite being at a higher risk of recurrent stroke, Chinese CVD survivors showed poor knowledge of stroke, and their intent to call EMS did not increase with recurrent stroke risk. Enhanced and stroke risk-orientated education on stroke recognition and proper response is needed for all CVD survivors.