bluuebunny/crossref_metadata_2025_split huggingface dataset:
CLÍNICA PSICANALÍTICA E SEGREGAÇÃO EM DISPOSITIVO DE INTERNAÇÃO PARA USUÁRIOS DE ÁLCOOL E OUTRAS DROGAS
Authors: Torres Maycon Rodrigo Da Silveira , Vidal Paulo Eduardo Viana 
Published: December 2020

Resumo: O presente artigo tem por objetivo discutir a tese de que o modelo de tratamento de usuários de drogas em regime de internação funciona como dispositivo de segregação. O percurso metodológico partiu da elaboração de casos clínicos de pacientes internados em enfermaria especializada de um hospital psiquiátrico, identificando uma relação de continuidade lógica entre as cenas de uso de drogas e a internação. A análise dos dados foi realizada com o aporte teórico da psicanálise de orientação lacaniana. De acordo com a teoria lacaniana dos discursos, os problemas associados ao uso de substâncias psicoativas, ou toxicomanias, são efeitos da relação entre o desenvolvimento do discurso científico e o avanço do capitalismo, na medida em que a ciência opera no real através de seu trabalho de formalização matemática e introduz no mercado novos objetos de consumo como as drogas. Enquanto o Discurso do Mestre induz a perda do objeto de gozo pela incidência da linguagem e produz um sujeito dividido, o Discurso do Capitalista se articula com a homogeneização do gozo operada pela ciência e aumenta o risco de abolição da subjetividade. Como efeito, o laço social que atravessa estes discursos é a segregação, expressa em diferentes formas de privação de liberdade. A prática psicanalítica sustenta o lugar do sujeito como resistência ao comando do mestre, impondo limites ao movimento institucional de suprimir a experiência subjetiva em nome de uma cura generalizada.Palavras-chave: Toxicomanias. Segregação. Psicanálise. Discurso do Mestre. Discurso do Capitalista.Abstract: This paper discusses a thesis on drug addict treatment as a segregation device. Its methods is based on clinical cases of patients admitted in specialized ward at psychiatric Hospital. It was identified association between hospitalization and places of drug intake as a logical continuity. Data was analyzed using Lacanian oriented psychoanalysis. Drug addiction is related to the development of the scientific discourse as science produces real from its work by mathematical formalization as capitalism expands and introduces new consumer goods. As Master Discourse induces a loss of jouissence object by incidence of language and produces a splitted subject, Capitalist Discourse is articulated to the homogenization of juissence made by science and increases risk of abolishing subjectivity. In consequence, segregation is the social bond that crosses these discourses and it is expressed by different means of freedom privation. Psychoanalytical treatment for drug addicts sustains a place for subject as resistence to mater´s command. It imposes a limit to institutional tendance to supress subjectivity for a generalized cure.Keywords: Drug addiction. Segregation. Psychoanalysis. Master Discourse. Capitalist Discourse.
Avaliação do perfil da resiliência e fatores associados em idosos comunitários [Assessment of resilience profile and associated factors in community elderly] [Evaluación del perfil de resiliencia y factores asociados en personas mayores de la comunidad]
Authors: Ferreira Gildiane Siqueira , Souto Rafaella Queiroga , Almeida Sandra Aparecida de , Ribeiro Gerson Da Silva , Araújo Gleicy Karine Nascimento de , Santos Rafael Da Costa 
Published: December 2020

Objetivo: identificar a prevalência de resiliência em idosos comunitários e sua relação com o apoio social e a satisfação com a vida. Método: estudo transversal, realizado com 159 idosos. Os dados foram obtidos por meio das escalas de Resiliência, Apoio Social e Satisfação com a vida. Resultados: apresentaram baixa resiliência os idosos do sexo feminino, com idade mais avançada, que não sabem ler e escrever, solteiros, residem sozinho, não trabalham, recebem até um salário mínimo, estão insatisfeitos com a vida e apresentam alto apoio social. Os idosos insatisfeitos tem 4,72 vezes mais probabilidade de apresentar baixo nível de resiliência. Foram encontradas correlações positivas entre a resiliência e o apoio social (p=0,022) e entre satisfação com a vida e a resiliência (p=0,000). Conclusão: a resiliência esteve relacionada com o apoio social e satisfação com a vida. ABSTRACTObjective: to identify the prevalence of resilience in older community members, and its relationship with social support and life satisfaction. Method: in this cross-sectional study of 159 older adults, data were obtained using Resilience, Social Support and Life Satisfaction scales. Results: low resilience was found in older adults who were female, older, single, lived alone, could not read and write, did not work, received up to 1 minimum wage, were dissatisfied with life, and had strong social support. Resilience was 4.72 times more likely to be low in dissatisfied older adults. Positive correlations were found between resilience and social support (p = 0.022), and between life satisfaction and resilience (p = 0.000). Conclusion: resilience was related to social support and life satisfaction.RESUMENObjetivo: identificar la prevalencia de la resiliencia en los miembros mayores de la comunidad y su relación con el apoyo social y la satisfacción con la vida. Método: en este estudio transversal de 159 adultos mayores, los datos se obtuvieron mediante escalas de Resiliencia, Apoyo Social y Satisfacción con la Vida. Resultados: se encontró baja resiliencia en adultos mayores que eran mujeres, mayores, solteros, vivían solos, no sabían leer ni escribir, no trabajaban, recibían hasta 1 salario mínimo, estaban insatisfechos con la vida y tenían un fuerte apoyo social. La resiliencia tenía 4,72 veces más probabilidades de ser baja en los adultos mayores insatisfechos. Se encontraron correlaciones positivas entre resiliencia y apoyo social (p = 0.022), y entre satisfacción con la vida y resiliencia (p = 0.000). Conclusión: la resiliencia se relacionó con el apoyo social y la satisfacción con la vida.
Effect of Alfalfa Cultivar and Bale Wrap Type on Dry Matter and Forage Quality of Large Round Bales in Outdoor Storage
Authors: Reiter Amanda S. , Sheaffer Craig C. , Wells M. Scotty , Grev Amanda M. , Hathaway Marcia A. , Lazarus Bill , Martinson Krishona 
Published: December 2020

HighlightsTime to bind a round bale was longest for twine (56 s) compared to B-Wrap® (28 s) and net wrap (18 s).Alfalfa cultivar had minimal effects on changes in dry matter and forage quality of round bales stored outdoors.Dry matter losses were 7% for twine bales, 5% for net wrap bales, while B-Wrap® bales maintained DM in outdoor storage.Deleterious changes in forage quality were generally observed after =180 days of outdoor storage. Abstract. Large round bales are commonly fed to livestock; however, it has been well documented that outdoor storage can negatively impact dry matter (DM) and forage quality. To reduce storage losses and improve feeding value, new wrap types and alfalfa cultivars have been developed; however, these options have not been extensively investigated. Therefore, the objectives of this research were to evaluate the time required to bind large round bales, determine changes in DM and forage quality, and examine the economics of reduced-lignin and conventional alfalfa hay bound in twine, net wrap, and B-Wrap® while in outdoor storage. Hay was baled into 24 large round bales; 12 bales each of reduced-lignin and conventional alfalfa. Within each cultivar, four replicates were bound with each wrap type. Using stopwatches, the time to bind each bale was recorded. At the time of harvest, and every 90±3 days for 365 days, individual bales were weighed and cored to determine changes in DM and forage quality. Significance was set at P = 0.05. Time to bind a bale was longest for twine, intermediate for B-Wrap®, and shortest for net wrap (P &lt; 0.01). Alfalfa cultivar had minimal effects on the parameters measured; therefore, the interaction between wrap type and storage length was reported. After 365 days in outdoor storage, DM losses were 7% for twine bales, 5% for net wrap bales, while B-Wrap® bales maintained DM. Changes in forage quality were observed at =180 days of storage where nonstructural carbohydrates were decreased and insoluble fiber components were concentrated. B-Wrap® bales had a higher value compared to net wrap and twines bales at 180 and 270 days in storage. These results suggest that B-Wrap® was better able to shed precipitation which preserved forage quality and bale value compared to large round bales bound in net wrap and twine in long term, outdoor storage. Keywords: B-Wrap®, Bale value, Net wrap, Reduced-lignin alfalfa, Twine.
Assessment of Heat Unit Availability and Potential Lint Yield of Cotton in Oklahoma
Authors: Masasi Blessing , Taghvaeian Saleh , Gowda Prasanna H , Moriasi Daniel N , Starks Patrick J 
Published: December 2020

HighlightsWater availability challenges have increased interest in cotton production in Oklahoma.An attempt was made to understand the feasibility of growing cotton in all counties of Oklahoma.Many areas in Oklahoma have sufficient thermal conditions for cotton production.Potential cotton lint yields generally increase from northern to southern areas of the state.Abstract. With the expansion of planted area, Oklahoma is increasingly becoming a major cotton producing state in the United States (U.S.). However, the feasibility of growing cotton in all counties of Oklahoma has not been determined. In this study, a heat unit based model was used to estimate the potential cotton lint yields (PCLYs) for all 77 counties of Oklahoma using 38 years (1981-2018) of air temperature data. PCLYs were estimated for optimal (no stress) conditions. The long-term total heat units (THUs) were more than 1000°C·d in 99% of counties, an indication that many areas in Oklahoma may have conducive thermal conditions for cotton production in most years. Similar to the THUs, the PCLYs generally increased from the northern to the southern counties of the state, and long-term averages ranged from 407 to 2472 kg ha-1. About 97% of the counties achieved long-term average PCLYs of at least 1000 kg ha-1. However, the results showed significant interannual variability of the estimated PCLYs in each county over the 38-year period. Low and high PCLYs mostly coincided with years characterized by cool and warm growing seasons, respectively. Reductions of PCLY ranging from 6% to 29% were observed when planting was delayed by just one week from the optimized planting date. This indicates that cotton producers need to carefully consider planting date to maximize cotton lint yield. As THUs were the only factor considered for calculating PCLYs in this study, future research should incorporate other variables such as rainfall and heat stress to improve PCLY estimations. Keywords: Air temperature, Planting date, Soil temperature, Yield gap, Yield variability.
Job (In)Security and Workers’ Training Decisions: A Framing Approach
Authors: Kamphuis Pascal , Glebbeek Arie C. 
Published: December 2020

Context: In this study, we attempt to contribute to the scarce evidence about the relationship between perceived labour market insecurity and worker training investments. Drawing on existing research into framing in decision-making, we investigate whether framing the labour market as insecure increases the willingness of workers to invest in training. We also investigate whether this effect is larger when training contract terms are favourable, such as when training is done mostly in an employer’s time, or when no payback clause is included.Approach: Data are gathered through a vignette-study under a sample of senior Dutch students, with experimental manipulation of frames. Respondents are given a questionnaire in which they are asked to imagine themselves working for a fictitious firm (but presented to them as real). The security/insecurity frames are elicited by randomly stressing either the positive or negative side of a series of events related to the labour market position of people working in this firm. Respondents are then asked to respond to five vignettes, each of these a randomly generated combination of training contract terms. For each vignette, respondents are asked to state whether or not they would be willing to go along with the specified training program under the conditions outlined in that vignette. Data are analysed with multilevel logistic regression. Findings: The willingness to train is not invariably greater under an insecurity frame. Instead, we find a crucial interaction: the willingness to train is greater under an insecurity frame when training-contract terms are favourable (e.g when no payback clause is included), but smaller when training-contract terms are unfavourable. Since the positive and negative effects are approximately equal in size, in a balanced design such as ours they cancel each other out, resulting in a close to zero overall effect for the frame variable.Conclusion: Our results suggest that, when workers are aware of the insecurity in their situation, this only makes them more willing to follow training when the risk of losing their investment is low.
Measuring and Tracking Personal Opportunity Outcome Measures Over 3 Years to Guide Policy and Services That Promote Inclusive Community Living
Authors: Cheng Sheng-Lun , Prohn Seb M. , Dinora Parthenia , Broda Michael D. , Bogenschutz Matthew 
Published: December 2020

Abstract
National policy and litigation have been a catalyst in many states for expanding personal outcomes for people with intellectual and developmental disabilities (IDD) and have served as an impetus for change in state IDD systems. Although several metrics are used to examine personal outcomes, the National Core Indicators (NCI) In-Person Survey (IPS) is one tool that provides an annual depiction of the lives of people who receive Medicaid Home and Community Based IDD waiver services (HCBS). This article examines whether a validated, three-factor (Privacy Rights, Everyday Choice, and Community Participation) measure of Personal Opportunity, derived from NCI items, functions as predicted across non-equivalent, NCI cohorts (N = 2400) from Virginia in 2017, 2018, and 2019. Multiple-groups confirmatory factor analysis (CFA) was employed to examine the invariance and generalizability of the Personal Opportunity constructs. Results indicated that Privacy Rights, Everyday Choice, and Community Participation measured the same concepts even when time and group varied. Significant improvements in Privacy Rights and Community Participation were observed when comparing latent factor means across years. Findings provide stakeholders with a tool for interpreting personal outcomes in the contexts of policy and practice intended to improve inclusion and quality of life for adults with IDD.
Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China
Authors: Yun Huan , Sun Liang , Wu Qingqing , Zong Geng , Qi Qibin , Li Huaixing , Zheng He , Zeng Rong , Liang Liming , Lin Xu 
Published: December 2020

Background
Animal studies suggest vital roles of sphingolipids, especially ceramides, in the pathogenesis of type 2 diabetes (T2D) via pathways involved in insulin resistance, β-cell dysfunction, and inflammation, but human studies are limited. We aimed to evaluate the associations of circulating sphingolipids with incident T2D and to explore underlying mechanisms.

Methods and findings
The current study included 826 men and 1,148 women who were aged 50–70 years, from Beijing and Shanghai, and without T2D in 2005 and who were resurveyed in 2011. Cardiometabolic traits were measured at baseline and follow-up surveys. A total of 76 sphingolipids were quantified using high-coverage targeted lipidomics. Summary data for 2-sample Mendelian randomization were obtained from genome-wide association studies of circulating sphingolipids and the China Health and Nutrition Survey (n = 5,731). During the 6-year period, 529 participants developed T2D. Eleven novel and 3 reported sphingolipids, namely ceramides (d18:1/18:1, d18:1/20:0, d18:1/20:1, d18:1/22:1), saturated sphingomyelins (C34:0, C36:0, C38:0, C40:0), unsaturated sphingomyelins (C34:1, C36:1, C42:3), hydroxyl-sphingomyelins (C34:1, C38:3), and a hexosylceramide (d18:1/20:1), were positively associated with incident T2D (relative risks [RRs]: 1.14–1.21; all P < 0.001), after multivariate adjustment including lifestyle characteristics and BMI. Network analysis further identified 5 modules, and 2 modules containing saturated sphingomyelins showed the strongest associations with increased T2D risk (RRQ4 versus Q1 = 1.59 and 1.43; both Ptrend < 0.001). Mediation analysis suggested that the detrimental associations of 13 sphingolipids with T2D were largely mediated through β-cell dysfunction, as indicated by HOMA-B (mediation proportion: 11.19%–42.42%; all P < 0.001). Moreover, Mendelian randomization evidenced a positive association between a genetically instrumented ceramide (d18:1/20:1) and T2D (odds ratio: 1.15 [95% CI 1.05–1.26]; P = 0.002). Main limitations in the current study included potential undiagnosed cases and lack of an independent population for replication.

Conclusions
In this study, we observed that a panel of novel sphingolipids with unique structures were positively associated with incident T2D, largely mediated through β-cell dysfunction, in Chinese individuals.
Physical, psychological and nutritional outcomes in a cohort of Irish patients with metastatic peritoneal malignancy scheduled for cytoreductive surgery (CRS) and heated intrapertioneal chemotherapy (HIPEC): An exploratory pilot study
Authors: Loughney Lisa , McCaffrey Noel , Timon Claire M. , Grundy Joshua , McCarren Andrew , Cahill Ronan , Moyna Niall , Mulsow Jurgen 
Published: December 2020

Background
Treatment for peritoneal malignancy (PM) can include cytoreductive surgery (CRS) and heated intrapertioneal chemotherapy (HIPEC) and is associated with morbidity and mortality. Physical, psychological and nutritional outcomes are important pre-operatively. The aim of this pilot study was to investigate these outcomes in patients with PM before and after CRS-HIPEC.

Methods
Between June 2018 and November 2019, participants were recruited to a single-centre study. Primary outcome was cardiopulmonary exercise testing (CPET) variables oxygen uptake (VO2) at anaerobic threshold (AT) and at peak. Secondary outcome measures were upper and lower body strength, health related quality of life (HRQoL) and the surgical fear questionnaire. Exploratory outcomes included body mass index, nutrient intake and post-operative outcome. All participants were asked to undertake assessments pre CRS-HIPEC and 12 weeks following the procedure.

Results
Thirty-nine patients were screened, 38 were eligible and 16 were recruited. Ten female and 6 male, median (IQR) age 53 (42–63) years. Of the 16 patients recruited, 14 proceeded with CRS-HIPEC and 10 competed the follow up assessment at week 12. Pre-operative VO2 at AT and peak was 16.8 (13.7–18) ml.kg-1.min-1 and 22.2 (19.3–25.3) ml.kg-1.min-1, upper body strength was 25.9 (20.3–41.5) kg, lower body strength was 14 (10.4–20.3) sec, HRQoL (overall health status) was 72.5 (46.3–80) % whilst overall surgical fear was 39 (30.5–51). The VO2 at AT decreased significantly (p = 0.05) and HRQoL improved (p = 0.04) between pre and post- CRS-HIPEC. There were no significant differences for any of the other outcome measures.

Conclusion
This pilot study showed a significant decrease in VO2 at AT and an improvement in overall HRQoL at the 12 week follow up. The findings will inform a larger study design to investigate a prehabilitation and rehabilitation cancer survivorship programme.
COVID-MATCH65—A prospectively derived clinical decision rule for severe acute respiratory syndrome coronavirus 2
Authors: Trubiano Jason A. , Vogrin Sara , Smibert Olivia C. , Marhoon Nada , Alexander Adrian A. , Chua Kyra Y. L. , James Fiona L. , Jones Nicholas R. L. , Grigg Sam E. , Xu Cecilia L. H. , Moini Nasreen , Stanley Sam R. , Birrell Michael T. , Rose Morgan T. , Gordon Claire L. , Kwong Jason C. , Holmes Natasha E. 
Published: December 2020

Objectives
We report on the key clinical predictors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and present a clinical decision rule that can risk stratify patients for COVID-19.

Design, participants and setting
A prospective cohort of patients assessed for COVID-19 at a screening clinic in Melbourne, Australia. The primary outcome was a positive COVID-19 test from nasopharyngeal swab. A backwards stepwise logistic regression was used to derive a model of clinical variables predictive of a positive COVID-19 test. Internal validation of the final model was performed using bootstrapped samples and the model scoring derived from the coefficients, with modelling performed for increasing prevalence.

Results
Of 4226 patients with suspected COVID-19 who were assessed, 2976 patients underwent SARS-CoV-2 testing (n = 108 SARS-CoV-2 positive) and were used to determine factors associated with a positive COVID-19 test. The 7 features associated with a positive COVID-19 test on multivariable analysis were: COVID-19 patient exposure or international travel, Myalgia/malaise, Anosmia or ageusia, Temperature, Coryza/sore throat, Hypoxia–oxygen saturation < 97%, 65 years or older—summarized in the mnemonic COVID-MATCH65. Internal validation showed an AUC of 0.836. A cut-off of ≥ 1.5 points was associated with a 92.6% sensitivity and 99.5% negative predictive value (NPV) for COVID-19.

Conclusions
From the largest prospective outpatient cohort of suspected COVID-19 we define the clinical factors predictive of a positive SARS-CoV-2 test. The subsequent clinical decision rule, COVID-MATCH65, has a high sensitivity and NPV for SARS-CoV-2 and can be employed in the pandemic, adjusted for disease prevalence, to aid COVID-19 risk-assessment and vital testing resource allocation.
The prognostic value of Presepsin for postoperative complications following pancreatic resection: A prospective study
Authors: Gasteiger Silvia , Primavesi Florian , Werkl Peter , Dostal Lucie , Gehwolf Philipp , Braunwarth Eva , Maglione Manuel , Sopper Sieghart , Öfner Dietmar , Stättner Stefan 
Published: December 2020

Background
Presepsin is involved in binding lipopolysaccharides and previous studies have confirmed its value as a marker for early diagnosis and prediction of severity in sepsis. Comparable studies assessing the predictive potential regarding postoperative complications and mortality following pancreatic resection are lacking.

Methods
This prospective study included 70 patients undergoing pancreatic resection from December 2017 until May 2019. Presepsin was measured preoperatively, on postoperative day 1, 3 and 8 (POD1/3/8) and correlated with the clinical course and mortality.

Results
Severe complications (Clavien-Dindo ≥3a) occurred in 28 patients (40%), postoperative pancreatic fistula (POPF) grade B/C occurred in 20 patients (28.6%), infectious complications in 28 (40%), and four patients (5.7%) died during hospital stay. Presepsin levels at any timepoint did not correlate with further development of postoperative complications or in-hospital mortality whereas CRP levels on postoperative day (POD) 3 were significantly associated with clinically relevant POPF (AUC 0.664, 95%CI 0.528–0.800; p = 0.033). Preoperative Presepsin levels as well as Presepsin on POD1 were significantly elevated in patients with malignant compared to benign underlying disease (299pg/ml vs. 174pg/ml and 693.5pg/ml vs. 294pg/ml; p = 0.009 and 0.013, respectively).

Conclusion
In our cohort, Presepsin was not eligible to predict the postoperative course following pancreatic resection. However, Presepsin levels were significantly elevated in patients with malignant disease, this finding warrants further investigation.