bluuebunny/crossref_metadata_2025_split huggingface dataset:
Permeability Damage and Supercritical Fluid Storage in the Cauvery Basin Neyveli Lignite Bed Containing Kaolinite Deposits during Alternative Injection of Brine and CO2
Authors: Rajkumar Perumal , Antony Justine K. , Mahalingam Selvaraj , Shankar Rakesh Ravi , Kesavakumar Ramadoss , R Venkat Pranesh. 
Published: August 2020

Abstract
A laboratory based investigation has been conducted on permeability damage and CO2 storage or retention in the lignite core during alternative injection of brine and supercritical carbon dioxide. Moreover, anthracite and bituminous coal beds were focused by the scientific community for effective production and reservoir formation damage study. But, now-a-days, lignite based coal bed methane reservoirs have attracted attention for productive exploitation and formation collapse investigation. Hence, for this purpose, a single component injection two phase (Brine + Supercritical CO2) coreflood test analysis under alternative injections were performed to investigate the occurrence of lignite structural collapse, permeability damage, injectivity decline and CO2 retention as well. The experimental study reveals that, due to gravity segregation there is a high rate of fluid saturation in lignite core and also, moderate level of heat transfer coefficient was also noted. Also, lignite core structural collapse under the brine and supercritical CO2 injection at different velocities resulted in huge volume of coal and kaolinite fines concentration. Kaolinite and coal fines migration resulted in pressure change and permeability decline in lignite core. The suspensions produced were passed to microstructural analysis and it revealed that kaolinite fine particle tends to possess a leaflet geometrical structure, which obstructed the cleats and restricted the fluid flow. Subsequently, hysteresis modelling (Pranesh 2018) was applied to this problem to quantify the amount of CO2 retention in lignite core. Additionally, statistical model, multiple linear regression was applied to this problem to validate the experimental model, which showed good agreement.
Differential response of digesta- and mucosa-associated intestinal microbiota to dietary black soldier fly (Hermetia illucens) larvae meal in seawater phase Atlantic salmon (Salmo salar)
Authors: Li Yanxian , Bruni Leonardo , Jaramillo-Torres Alexander , Gajardo Karina , Kortner Trond M. , Krogdahl Åshild 
Published: August 2020

Abstract
Background: Intestinal digesta is commonly used for studying responses of microbiota to dietary shifts, yet evidence is accumulating that it represents an incomplete view of the intestinal microbiota. The present work aims to investigate the differences between digesta- and mucosa-associated intestinal microbiota in Atlantic salmon ( Salmo salar ) and how they may respond differently to dietary perturbations. In a 16-week seawater feeding trial, Atlantic salmon were fed either a commercially-relevant reference diet or an insect meal diet containing ~15% black soldier fly ( Hermetia illucens ) larvae meal. The digesta- and mucosa-associated distal intestinal microbiota were profiled by 16S rRNA gene sequencing. Results: Regardless of diet, we observed substantial differences between digesta- and mucosa-associated intestinal microbiota. Microbial richness and diversity were much higher in the digesta than the mucosa. The insect meal diet altered the distal intestinal microbiota resulting in higher microbial richness and diversity. The diet effect, however, depended on the sample origin. Digesta-associated intestinal microbiota showed more pronounced changes than the mucosa-associated microbiota. Multivariate association analyses identified two mucosa-enriched taxa, Brevinema andersonii and unclassified Spirochaetaceae , associated with the expression of genes related to immune responses and barrier function in the distal intestine, respectively. Conclusions: Our data show that salmon intestinal digesta and mucosa harbor microbial communities with clear differences. Mucosa-associated intestinal microbiota seems more resilient to variations in the diet composition than digesta-associated intestinal microbiota. To fully unveil the response of intestinal microbiota to dietary changes, concurrent profiling of digesta- and mucosa-associated intestinal microbiota is recommended whenever feasible.
Case Control Association Study of WNT Signaling Pathway-related Genes and Osteoporosis Risk Among Chinese Postmenopausal Women
Authors: Yang Zhe , Liu Jie , Fu Jinjin , Chai Zijia , Li Shuwen , Sun Yie 
Published: August 2020

Abstract
Background: The WNT signaling pathway is involved in the regulation of bone homeostasis, and the effects of WNT signaling pathway related genes (WLS, WNT16 and LRP5) on osteoporosis risk among Chinese postmenopausal women is still unknown. Hence, we performed a case-control study to assess the association of WNT signaling pathway related genes and osteoporosis risk.Methods: This study involved 1026 women (515 osteoporosis patients and 511 controls) of postmenopausal age who were randomly sampled from Xi'an 630 Hospital, Shaanxi Province, China. Eleven genetic polymorphisms in WLS (rs2566755, rs12407028, rs2566752 and rs7554551), WNT16 (rs3779381, rs3801387, rs917727 and rs7776725) and LRP5 (rs2291467, rs11228240 and rs12272917) were selected and genotyped using the Agena MassARRAY iPLEX system. The association of the genetic polymorphisms and osteoporosis risk was assessed by odds ratios and 95% confidence intervals. The Multifactor Dimensionality Reduction (MDR) method was conducted to analyze SNP-SNP interaction.Results: We found that LRP5 polymorphisms (rs2291467, rs11228240 and rs12272917) were significantly associated with a decreased risk of osteoporosis in homozygotes, both in recessive and additive models (P < 0.05). Stratification analysis showed that LRP5 polymorphisms (rs2291467, rs11228240 and rs12272917) significantly decreased the osteoporosis risk in the subgroup of BMI ≤ 24 (P < 0.05) and that individuals carrying a heterozygote genotype of WNT16 polymorphisms (rs3779381, rs3801387, rs917727 and rs7776725) had a higher osteoporosis risk in the subgroup of BMI > 24 (P < 0.05). We observed that three blocks (block 1: rs2566755 and rs12407028, block 2: rs3779381, rs3801387, rs917727 and rs7776725, block 3: rs2291467 and rs11228240), Trs2291467Trs11228240 and Crs2291467Crs11228240 had a strong association with a lower risk of osteoporosis. Additionally, MDR analysis revealed that a four-locus model (rs2566752 and rs2566755 in WLS, rs7776725 in WNT16, rs12272917 in LRP5) was significantly associated with osteoporosis risk. Conclusions: Our findings suggested that WLS, WNT16 and LRP5 genetic polymorphisms were associated with osteoporosis risk among Chinese postmenopausal women.
Laparoscopic Surgery and Robot-Assisted Surgery for Colorectal Cancer With Persistent Descending Mesocolon
Authors: Kojima Yutaka , Sakamoto Kazuhiro , Kawai Masaya , Okazawa Yu , Kure Kazumasa , Kobari Aya 
Published: August 2020

Abstract
Background: Persistent descending mesocolon (PDM) is a case of colonic replacement and adhesion as a result of abnormal fixation of the gastrointestinal tract. In laparoscopic surgery, it is performed when the patient is in an unconscious state. However, laparoscopic surgery, especially robot-assisted surgery, may necessarily need to devise surgical procedures such as anatomical recognition and adhesion detachment. We herein report three patients with PDM that were treated with arthroscopic surgery at our hospital. Case presentation: Patient 1: a 73-year-old man with sigmoid colon cancer. Laparoscopic sigmoidectomy was performed, and there were no problems encountered (such as difficulty in recognizing the anatomical location) other than adhesion detachment. Robot-assisted surgery was performed to the other two patients. Patient 2: a 62-year-old man with lower rectal cancer and underwent an intersphincteric resection. Patient 3: a 76-year-old man with lower rectal cancer and underwent Hartmann's operation. The surgery duration of these patients took longer, the same with robot-assisted surgeries without PDM. Conclusions: Robot-assisted surgeries have a large magnifying effect on delicately removing adhesions, which is a characteristic of PDM. Also, some parts are difficult to grasp as a whole, and it takes time to recognize adhesions anatomically and to grasp the whole image. Here, we report our experience with laparoscopic surgery and robot-assisted surgery for left-sided colorectal cancer with PDM.
Use of Oral Citrulline Administration as a Mitigation Strategy for Fescue Toxicosis in Sheep
Authors: Greene Maslyn A , Klotz James L , Goodman Jack P , May John B , Harlow Brittany M , Baldwin William S , Strickland James R , Britt Jessica L , Schrick F. N. , Duckett Susan K 
Published: August 2020

Abstract
Background: Gestating ewes consuming ergot alkaloids, from endophyte-infected (E+) tall fescue seed, produce smaller lambs suffering from intrauterine growth restriction. Arginine (Arg) supplementation has been shown to increase birth weight and oral citrulline (Cit) administration is reported to increase arginine concentrations. Two experiments were conducted to: 1) evaluate if oral supplementation with Cit or water, to ewes consuming E+ fescue seed, increases lamb birth weight and 2) determine the effectiveness of Cit and citrulline:malate as an oral drench in elevating circulating levels of Cit to determine dosing levels and frequency of dose. In Experiment 1, gestating Suffolk ewes (n = 10) were assigned to one of two treatments [oral drench of citrulline-malate 2:1 (CITM; 81 mg/kg/d of citrulline) or water (TOX)] to start on d 86 of gestation. In Experiment 2, non-pregnant Suffolk ewes (n = 3) were assigned to either oral citrulline (CIT; 81 mg/kg/d), citrulline-malate 2:1 (CITM; 81 mg/kg/d of citrulline), or water (CON) drench in a Latin Square design for a treatment period of 4 d with a washout period of 3 d. On d 4, blood samples were collected at 0, 0.5, 1, 2, 3, 4, 6, 8, 10, 12, and 18 h post drench.Results:Expt 1: Ewes on CITM treatment had decreased (P < 0.05) plasma Arg and Cit concentrations during gestation. At birth, lambs from CITM ewes had reduced (P < 0.05) crude fat and total fat but did not differ (P > 0.05) in birth weight from lambs born to TOX ewes. Expt 2: Oral drenching of CIT and CITM increased (P < 0.0001) Cit concentrations within 2 h and levels remained elevated for 8 h. Apparent half-life of elimination for CIT and CITM were 8.484 h and 10.392 h respectively.Conclusions: Our results show that lamb birth weight was not altered with a single oral drench of citrulline-malate; however, lamb body composition was altered. The level and frequency of citrulline dosing may need to be greater in order to observe consistent elevation of Cit/Arg concentrations to determine its effectiveness in mitigating fescue toxicosis.
Multibody Simulation for Gravity-Driven Falling Film Using Computational Fluid Dynamics
Authors: Iglesias Susana Marrero , Dominguez Dany Sanchez , Mazaira Leorlen Yunier Rojas , Escrivá Alberto , Muñoz-Cobo José Luis , Rivera Yago , Berna Cesar 
Published: August 2020

The annular flow two-phase regime appears in nuclear power plants cooling by water. On accidents with lost of cooling this regime determine the heat extraction conditions from the core. The experimental facility Gerador de Película Ondulatoria (GEPELON) was constructed at Universitat Politècnica de València to study this phenomenon. In this work, we use computational fluid dynamics techniques to simulate an air-water regime, specifically a gravity-driven falling liquid film in the GEPELON experimental facility. We consider a multibody geometry where the porous sintered of the input device is simulated in a realistic way. The Volume of Fluid (VOF) model was used in the resolution of the constitutive equations. We propose three geometric approximations to estimate film thickness, and simulation results were compared with experimental values. The simulation results show a good agreement with experimental measurements. Besides, no significant differences were observed between geometrical approximations for film thickness calculations.
ON SPIN HAMILTONIAN FITS TO MÖSSBAUER SPECTRA OF NiFe2O4 NANOPARTICLES SYNTHESIZED BY CO-PRECIPITATION
Authors: Dias Filho Jose Higino , Aguilar Jorge Luis López , De Albuquerque Adriana Silva , Maia Renato Dourado , Barbosa Wesley de Oliveira , Ferreira Ernando Campos , Pereira Fellipe Silva , Benfica Kátia Ferreira Guimarães 
Published: August 2020

Nanocrystalline NiFe2O4 particles prepared by chemical co-precipitation method were studied using magnetic measurements, 57Fe Mössbauer spectroscopy, X-ray diffraction, and transmission electron microscopy. Fits to Mössbauer spectra, in the range of 4.2 K – 300 K, were done using spin hamiltonians to describe both the electronic and nuclear interactions, a model of superparamagnetic relaxation of two levels (spin ½) and stochastic theory, a log-normal particle size distribution function as well as a dependency of the magnetic transition temperature and the anisotropy constant on particle diameter. We have used evolutionary strategies to fit the more complex Mössbauer spectra line shapes. The nanoparticles have an average size of 7 nm and exhibit superparamagnetism at room temperature. The saturation magnetization (Ms) at 4.2 K was determined from M vs. 1/H plots by extrapolating the value of magnetizations to infinite fields, to 24.21 emu/g and coercivity to 3.15 kOe. A magnetic anisotropy energy constant (K) 1.9´105 J/m3, at 4.2 K, were calculated from magnetization measurements. The synthesis, characterization, and functionalization of magnetic nanoparticles is a highly active area of current research located at the interface between materials science, biotechnology, and medicine. Superparamagnetic iron oxides nanoparticles have unique physical properties and have emerged as a new class of diagnostic probes for multimodal tracking and as contrast agents for magnetic resonance imaging (MRI).
PARAMETERIZATION OF MAGNETIC NANOPARTICLES MATHEMATICAL MODEL USING EVOLUTIONARY ALGORITHMS
Authors: Barbosa Wesley de Oliveira , Maia Renato Dourado , Dias Filho Jose Higino 
Published: August 2020

In this paper, the evolutionary algorithms approach is applied to the parameterization of a mathematical model describing the Mössbauer spectra of nanogranular (or nanoparticle) magnetic systems. These systems exhibit physical properties very different from bulk specimens being of great interest for material science and its use as biosensors, magneto sensors, data storage, and magnetic fluids. The purpose of this work is to compare the performance between the Differential Evolution and the Evolutionary Strategies algorithms to optimize the model parameters which best fit the experimental Mössbauer spectra of nanoscale magnetic particles. Spectra of two samples (??iron foil and NiFe2O4 nanoparticles) were recorded, at room temperature, by a conventional Mössbauer spectrometer using a scintillation detector in transmission geometry with a 57Co/Rh source. Fits to Mössbauer spectra were done using spin hamiltonians to describe both the electronic and nuclear interactions; a model of superparamagnetic relaxation of two levels (spin ½) and stochastic theory; a lognormal particle size distribution function as well as a dependency of the magnetic transition temperature and the anisotropy constant on particle diameter. The evolutionary algorithms have been implemented using Python programming language. For comparison, the two algorithms obey the termination criterion of 6,000 evaluations of the objective function. The results presented show the efficiency of these algorithms in the optimization of the parameters and on the fits of the spectra.
SIMULATION OF PULSATILE FLOW THROUGH ARTERIAL TREE MODELS
Authors: Santos Igor Pires dos , Reis Ruy Freitas , Queiroz Rafael Alves Bonfim de 
Published: August 2020

In this work, an analytical scheme for evaluating the local wave characteristics of flow and pressure in 1D arterial tree’s models is implemented. An interactive computational environment was developed to simulate this scheme. The presented environment contains a compact class structure to enable the iteration and visualization of multiple objects. The results obtained are consistent with those from literature. The software developed provides the visualization of a blood flow simulation through a simple user interface.
A BAYESIAN APPROACH FOR THE SOLUTION OF INVERSE PROBLEMS TO ESTIMATE RADIATIVE PROPERTIES
Authors: Da Silva Cairo Martins , Guedes Gustavo Antunes , Abreu Luiz Alberto da Silva , Knupp Diego Campos , Da Silva Neto Antônio José 
Published: August 2020

The main objective of the present work is related to the formulation and solutionof inverse problems in radiative heat transfer phenomena. The analysis consists in estimating parameters and functions of a participanting medium, such as optical thickness, single scattering albedo, diffusive reflectivities and phase function coefficients. It is performed with the numerical application of a Bayesian framework, which includes “Maximum a Posteriori” (MAP) and "Markov Chains Monte Carlo"(MCMC), within the Metropolis-Hastings procedure. These methodologiesproved to be effective for solving such problems.
Artificial neural network modeling approach for the prediction of five-day biological oxygen demand and wastewater treatment plant performance
Authors: Alsulaili Abdalrahman , Refaie Abdelrahman 
Published: August 2020

Abstract
The measurement of the wastewater BOD5 level requires five days, and the use of a prediction model to estimate BOD­5 saves time and enables the adoption of an online control system. This study investigates the application of artificial neural networks (ANNs) in predicting the influent BOD5 concentration and the performance of WWTPs. The WWTP performance was defined in terms of the COD, BOD, and TSS concentrations in the effluent. Sensitivity analysis was performed to identify the best-performing ANN network structure and configuration. The results showed that the ANN model developed to predict the BOD concentration performed the best among the three outputs. The top-performing ANN models yielded R2 values of 0.752, 0.612, and 0.631 for the prediction of the BOD, COD, and TSS concentrations, respectively. The optimal performing models were obtained (three inputs – one output), which indicated that the influent temperature and conductivity greatly affect the WWTP performance as inputs in all models. The developed prediction model for the influent BOD5 concentration attained a high accuracy, i.e., R2 = 0.754, which implies that the model is viable as a soft sensor for online control and management systems for WWTPs. Overall, the ANN model provides a simple approach for the prediction of the complex processes of WWTPs.
Dynamics of the behaviour of a vertical wetland (French system) operating in warm-climate conditions, evaluated by means of variables continuously measured in situ
Authors: de Andrade Moraes Mirene A. , Zumalacarregui Jorge A. García , Trein Camila Maria , von Sperling Marcos 
Published: August 2020

Abstract
The sewage treatment system in this study was operated with only the first stage of a French system of vertical wetlands, composed of two units in parallel and running with an extended feeding cycle (7 days). This research sought to evaluate and relate continuous variables measured in situ (dissolved oxygen (DO), pH and redox potential) throughout the feeding cycle, with measurements at distinct heights along the filter vertical profile. Additionally, the influence of the surface organic sludge deposit was investigated. A close link between the hydraulic behaviour and the effluent quality was verified, with both being related to the batch volume and the instantaneous hydraulic loading rate. The drop in DO as the feed days progressed could be related to the loss of hydraulic conductivity. A thicker sludge layer decreased the aeration capacity of the filter. The effluent was observed to be aerated when percolating through the medium. DO and pH data suggested that nitrification varied along the filter depth, the batch duration and the feed cycle. The monitored parameters may be indicative of the behaviour of other parameters.
Systematic Review of Glucagon-Like Peptide One Receptor Agonist Liraglutide of Subjects with Heart Failure with Reduced Left Ventricular Ejection Fraction
Authors: Hamad Farah , Elnour Asim Ahmed , Elamin Abdelgadir , Mohamed Sasha , Yousif Isra , Don Judit , Abdi Semira , Al Amoodi Abdulla , Fathelrahman Ahmed Ibrahim , Gnana Kishore , Alanzi Fahad , Abubakar Abubakar B , Magboul Salma Mohammed , Ahmed Sahar Asim , Sadeq Adel 
Published: August 2020

Background::
The major cardiovascular outcome trials on glucagon-like peptide one-receptor
agonists have examined its effect on hospitalization of subjects with heart failure; however,
very limited trials have been conducted on subjects with reduced left ventricular ejection fraction (r-
LVEF) as a primary outcome.

Objective::
We have conducted a systematic review of two major (FIGHT and LIVE) placebo-controlled
trials of liraglutide and its clinical effect on the ejection fraction of subjects with heart failure.

Methods::
Medline data was retrieved for trials involving liraglutide from 2012 to 2020. The inclusion
criteria for trials were: subjects with or without type 2 diabetes mellitus (T2DM), subjects
with heart failure with rLVEF, major trials (phase II or III) on liraglutide, trials included liraglutide
with defined efficacy primary outcome of patients with heart failure with rLVEF. The search was
limited to the English language, whereby two trials [FIGHT and LIVE] had been included and
two trials were excluded due to different primary outcomes. Participants (541) had been randomized
for either liraglutide or placebo for 24 weeks.

Results::
In the FIGHT trial the primary intention-to-treat, sensitivity, and diabetes subgroup analyses
have shown no significant between-group difference in the global rank scores (mean rank of
146 in the liraglutide group versus 156 in the placebo group; Wilcoxon rank-sum P=.31), number
of deaths, re-hospitalizations for heart failure, or the composite of death or change in NT-pro BNP
level (P= .94). In the LIVE trial, the change in the left ventricular ejection fraction (LVEF) from
baseline to week 24 was not significantly different between treatment groups. The overall discontinuation
rate of liraglutide was high in the FIGHT trial (29%, 86) as compared to that in the LIVE
trial (11.6%, 28).

Conclusion::
FIGHT and LIVE trials have demonstrated that liraglutide use in subjects with heart
failure and rLVEF was implicated with an increased adverse risk of heart failure-related outcomes.