bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extracellular matrix and wall composition are diverse in the organogenic and non-organogenic calli of Actinidia arguta
Authors: Popielarska-Konieczna Marzena , Sala Katarzyna , Abdullah Mohib , Tuleja Monika , Kurczyńska Ewa 
Published: March 2020

AbstractKey messageDifferences in the composition and the structural organisation of the extracellular matrix correlate with the morphogenic competence of the callus tissue that originated from the isolated endosperm of kiwifruit.AbstractThe chemical composition and structural organisation of the extracellular matrix, including the cell wall and the layer on its surface, may correspond with the morphogenic competence of a tissue. In the presented study, this relationship was found in the callus tissue that had been differentiated from the isolated endosperm of the kiwiberry,Actinidia arguta. The experimental system was based on callus samples of exactly the same age that had originated from an isolated endosperm but were cultured under controlled conditions promoting either an organogenic or a non-organogenic pathway. The analyses which were performed using bright field, fluorescence and scanning electron microscopy techniques showed significant differences between the two types of calli. The organogenic tissue was compact and the outer walls of the peripheral cells were covered with granular structures. The non-organogenic tissue was composed of loosely attached cells, which were connected via a net-like structure. The extracellular matrices from both the non- and organogenic tissues were abundant in pectic homogalacturonan and extensins (LM19, LM20, JIM11, JIM12 and JIM20 epitopes), but the epitopes that are characteristic for rhamnogalacturonan I (LM5 and LM6), hemicellulose (LM25) and the arabinogalactan protein (LM2) were detected only in the non-organogenic callus. Moreover, we report the epitopes, which presence is characteristic for theActinidiaendosperm (LM21 and LM25, heteromannan and xyloglucan) and for the endosperm-derived cells that undergo dedifferentiation (loss of LM21 and LM25; appearance or increase in the content of LM5, LM6, LM19, JIM11, JIM12, JIM20, JIM8 and JIM16 epitopes).
Survival prediction for patients with non-resectable intrahepatic cholangiocarcinoma undergoing chemotherapy: a retrospective analysis comparing the tumor marker CA 19-9 with cross-sectional imaging
Authors: Hahn Felix , Müller Lukas , Jungmann Florian , Mähringer-Kunz Aline , Tanyildizi Yasemin , Düber Christoph , Galle Peter R. , Weinmann Arndt , Kloeckner Roman 
Published: March 2020

AbstractPurposeCarbohydrate antigen (CA) 19-9 has been established as the main serum marker for patients with intrahepatic cholangiocarcinoma (ICC). The aim of this study was to compare the prognostic value of CA 19-9 changes versus response determined by imaging in patients with ICC undergoing chemotherapy.MethodsBetween 2003 and 2018, 151 patients with histopathologically confirmed ICC underwent chemotherapy at our tertiary care center for non-resectable or recurrent ICC, of whom 121 were included in this study. Serum CA 19-9 levels and imaging were retrospectively evaluated during chemotherapy. Log-rank testing and optimal stratification were used to classify patients into risk groups.ResultsPrior to chemotherapy, baseline serum CA 19-9 levels above the previously published cut-off of 37 U/ml were associated with poor survival (median OS 8.7 vs. 12.4 months,p = 0.003). After the beginning of chemotherapy, an increase in CA 19-9 of more than 40 U/ml resulted in impaired residual survival (median OS 5.0 vs. 12.1 months,p < 0.001). However, progressive disease at the first follow-up imaging proved the strongest predictor for poor outcome (median OS 4.6 vs. 15.5 months,p < 0.001). In contrast to prior studies, our data did not show statistically relevant differences in survival time with respect to absolute or relative decreases in serum CA 19-9 levels.ConclusionIn our study, the disease control rate—that is, the absence of progressive disease—was the strongest predictor of prolonged residual OS. To this end, both CA 19-9 changes and progressive disease on initial follow-up showed remarkable discriminatory power, with the latter slightly outperforming the former. Therefore, imaging should remain the mainstay of patient evaluation during follow-up.
Formula-E race strategy development using artificial neural networks and Monte Carlo tree search
Authors: Liu Xuze , Fotouhi Abbas 
Published: March 2020

AbstractEnergy management has been one of the most important parts in electric race strategies since the Fédération Internationale de l’Automobile Formula-E championships were launched in 2014. Since that time, a number of unfavorable race finishes have been witnessed due to poor energy management. Previous researches have been focused on managing the power flow between different energy sources or different energy consumers based on a fixed cycle. However, there is no published work in the literature about energy management of a full electric racing car on repeated course but with changeable settings and driving styles. Different from traditional energy management problems, the electric race strategy is more of a multi-stage decision-making problem which has a very large scale. Meanwhile, this is a time-critical task in motorsport where fast prediction tools are needed and decisions have to be made in seconds to benefit the final outcome of the race. In this study, the use of artificial neural networks (ANN) and tree search techniques is investigated as an approach to solve such a large-scale problem. ANN prediction models are developed to replace the traditional lap time simulation as a much faster performance prediction tool. Implementation of Monte Carlo tree search based on the proposed ANN fast prediction models has provided decent capability to generate decision-making solution for both pre-race planning and in-race reaction to unexpected scenarios.
Friction embossing
Authors: Zou W. , Schomburg W. K. 
Published: March 2020

AbstractA new fabrication process for micro structures from thermoplastic polymers is presented. Two layers of thermoplastic polymer are placed onto a tool with micro structures. By a friction welding machine, the polymer surfaces are rubbed against each other generating friction heat and melting the polymer. The polymer adapts to the surface shape of the micro structures on the tool. Then, the movement of the machine stops and the polymer cools down and hardens in the shape of the micro structures. The entire process is finished within a few seconds and the required investment costs are in the range of some 10,000 € to approximately 200,000 €. Compared to ultrasonic hot embossing, samples with larger overall dimensions can be fabricated and the heat distribution has been proven to be more homogeneous.
Therapeutic effect of high-efficiency online hemodiafiltration for recurrent restless legs syndrome in dialysis patients
Authors: Sakurai Kenji , Saito Takeshi , Hosoya Hiromi , Kurihara Yoshitaka , Yamauchi Fumi 
Published: March 2020

AbstractTwo dialysis patients developed recurrent restless legs syndrome. The clinical courses and the association between the α1-microglobulin removal rate and the therapeutic effects of hemodiafiltration were analyzed. Case 1: a middle-aged woman was switched from predilution online hemodiafiltration to hemodialysis, following which the α1-microglobulin removal rate decreased from 39.1 to 29.9%. A month later, the severe restless legs syndrome occurred. The treatment was then switched to high-efficiency hemodiafiltration and 2 weeks later, these symptoms were resolved. The α1-microglobulin removal rate increased to 41.9%. Her symptoms recurred 5 years later with severity; thus, the hemodiafiltration treatment conditions were changed. Under revised conditions, the α1-microglobulin removal rate was 42.6%, and her symptoms were alleviated. Continuation of high-efficiency hemodiafiltration led to the resolution of the syndrome at 1 month after recurrence. Case 2: a middle-aged man on hemodialysis developed the restless legs syndrome in the second year of treatment. The α1-microglobulin removal rate was 23.8%. After switching to a month-long high-efficiency hemodiafiltration with a removal rate of ≥ 40%, his symptoms were resolved. However, the syndrome recurred after a year with severity. The symptoms were alleviated using various measures. The hemodiafilters were changed, and hemodiafiltration with an α1-microglobulin removal rate of ≥ 40% was continued; 2 months later, his symptoms resolved. High-efficiency online hemodiafiltration is an effective therapeutic strategy for restless legs syndrome in dialysis patients. We found, for the first time, that target removal efficiency is an α1-microglobulin removal rate of 40% or higher.
Stopover dynamics of 12 passerine migrant species in a small Mediterranean island during spring migration
Authors: Maggini Ivan , Trez Marta , Cardinale Massimiliano , Fusani Leonida 
Published: March 2020

AbstractSmall coastal islands offer landing opportunities for large numbers of migratory birds following long sea crossings. However, they do not always provide sufficient refueling opportunities, thus raising questions about their importance for the success of migratory journeys. Here we analyzed a large dataset collected during 3 years of captures and recaptures of 12 species on the island of Ponza, central Italy, to determine the importance of the island for refueling. Despite the very large amount of birds on the island, only a very small fraction (usually below 2%) stayed on the island for longer than 1 day. These birds had low energy stores and, in most cases, they were not able to successfully refuel on Ponza. Only two species (Subalpine Warbler and Common Chiffchaff) had a positive fuel deposition rate, possibly as a result of the better suitability of the island’s habitat to these two species. We underline that the large use of the island despite the relatively low refueling opportunities may be due to other aspects that it may offer to the birds. Possibly, birds just landed after a long sea crossing may require a short rest or sleep and can find opportunities to do that on the islands, reinitiating their onward flight after just a few hours. Understanding the role of these islands for migratory birds will be important for conservation, since setting priorities for protection might be misled if considering only refueling success as an important variable.
Effect of the Neurofeedback-EEG Training During Physical Exercise on the Range of Mental Work Performance and Individual Physiological Parameters in Swimmers
Authors: Mikicin Mirosław , Mróz Anna , Karczewska-Lindinger Magdalena , Malinowska Karolina , Mastalerz Andrzej , Kowalczyk Marek 
Published: March 2020

AbstractThe aim of the study was to demonstrate the effects of the Neurofeedback-EEG training during physical exercise on the improvements in mental work performance and physiological parameters. The study examined seven swimmers based on the following anthropometric measurements: body height, body mass and body composition. The Kraepelin’s work curve test, EEG and EMG during physical exercise were also performed. The athletes followed 20 Neurofeedback-EEG training sessions on the swimming ergometer for 4 months. Most mean indices of partial measures of the work curve were significantly modified (p < 0.05) following the Neurofeedback-EEG training. Mean level of maximal oxygen uptake in study participants was over 55 ml/kg/min, with statistically significant differences documented between the first and the second measurements. No significant differences were found in the fatigue rate between the measurements 1 and 2. The improved mental work performance following the Neurofeedback-EEG training facilitates optimization of psychomotor activities.
High-precision collinear laser spectroscopy at the Collinear Apparatus for Laser Spectroscopy and Applied Physics (COALA)
Authors: Imgram Phillip , König Kristian , Krämer Jörg , Ratajczyk Tim , Maaß Bernhard , Müller Patrick , Sommer Felix , Nörtershäuser Wilfried 
Published: March 2020

AbstractCOALA is a new offline collinear laser spectroscopy setup for high-precision measurements and development work at TU Darmstadt, Germany. An introduction to the technique and the experimental setup is given and an overview of current projects with recent results is presented. The idea of a novel all-optical absolute charge radius determination is discussed.
Composition analysis and minimal treatments to solubilize polysaccharides from the brown seaweed Laminaria digitata for microbial growth of thermophiles
Authors: Allahgholi Leila , Sardari Roya R. R. , Hakvåg Sigrid , Ara Kazi Z. G. , Kristjansdottir Thordis , Aasen Inga Marie , Fridjonsson Olafur H. , Brautaset Trygve , Hreggvidsson Gudmundur Oli , Karlsson Eva Nordberg 
Published: March 2020

AbstractBrown macroalgae (Phaeophyta) hold high potential as feedstock for biorefineries due to high biomass productivity and carbohydrate content. They are, however, a challenging, unconventional feedstock for microbial refining and several processing problems need to be solved to make them a viable option. Pre-treatment is necessary to enhance accessibility and solubility of the biomass components but should be minimal and mild to assure sustainable and cost-effective processing. Here, two routes to pre-treatLaminaria digitata to release polysaccharides were investigated: hot water pre-treatment by autoclaving (121 °C, 20 min or 60 min) and a two-step extraction with mild acid (0.1 M HCl) followed by alkaline treatment. Hot water pre-treatment resulted in partial extraction of a mixture of polysaccharides consisting of alginate, fucoidan and laminarin. After mild acid pre-treatment, alginate was found in the remaining insoluble residues and was extracted in a second step via alkaline treatment using Na2CO3 (0.15 M) at 80 °C and CaCl2 (10%) for the precipitation. In addition to carbohydrates, a fraction of other components such as proteins, phenolic compounds, minerals and trace elements was detected in the extracts. Cultivation of the thermophilic bacterial strains Rhodothermus marinus DSM 16675 and Bacillus methanolicus MGA3 (ATCC 53907) in media supplemented with the respective extracts resulted in growth of both strains, indicating that they were able to utilize the available carbon source for growth. R. marinus displayed the highest cell density in the medium containing the extract from acid pre-treatment, whereas B. methanolicus growth was highest with the extract from hot water pre-treatment.
The locus of the representation of logarithmic connections by Fuchsian equations
Authors: Ivanics Péter 
Published: March 2020

AbstractThe generic element of the moduli space of logarithmic connections with parabolic points on holomorphic vector bundle over the Riemann sphere can be represented by a Fuchsian equation with some singularities and some apparent singularities. We analyze the case of rank 3 vector bundle which leads to third order Fuchsian equation. We find coordinates on an open subset of the moduli space and we construct a non-trivial part of the moduli space by blowing up along a variety in a special case.
Market governance, financial innovation, and financial instability: lessons from banks’ adoption of shareholder value management
Authors: Pernell Kim 
Published: March 2020

AbstractAs the economy has grown increasingly financialized, the relationship between financial innovation and instability has attracted more attention. Previous research finds that the proliferation of complex financial innovations, like asset securitization and new financial derivatives, helped to erode the market governance arrangements that kept excessive bank risk-taking in check, inviting instability. This article presents an alternative way of understanding how financial innovations and market governance arrangements combine to shape instability. Market governance arrangements also shape how financial firmsreceiveinnovations, leading to greater or lesser instability at particular times and places. I illustrate this argument by tracing the effects of changing corporate governance arrangements at large US banks in the 1990s and 2000s. Like non-financial firms in the preceding decade, banks adopted reforms associated with the shareholder value model of corporate governance. These changes to internal bank governance arrangements affected the agendas of bank executives in ways that encouraged expanded use of securitization and derivatives. Drawing from this case, I argue that a full understanding of instability in the financialized era requires closer attention to the (institutionally-structured) interests of financial innovationusers—not just to features of financial innovations themselves.
3-Year results of arthroscopic management of lateral clavicle fractures
Authors: Dey Hazra Rony-Orijit , Blach Robert , Ellwein Alexander , Lill Helmut , Jensen Gunnar 
Published: March 2020

Abstract
Background
In 18% of clavicular fractures, the lateral part is affected. Recently, a variety of surgical techniques have been discussed. This study aimed to analyze clinical and radiological results of a consecutive case series with arthroscopy-only coracoclavicular stabilization in unstable lateral clavicle fractures of Neer type IIB, utilizing a double-button fixation technique.

Methods
Between 2013 and 2015 we followed up ten patients who exclusively had an arthroscopically assisted augmentation of the coracoclavicular ligaments using a double-button fixation (Dog Bone, Arthrex, Naples, FL, USA). Radiological scores and functional outcome measures were evaluated: Subjective Shoulder Value (SSV), Constant–Murley Score (CMS), Taft Score (TF), ASES Score (ASES), Nottingham Clavicle Score (NCS), and a Visual Analogous Scale (VAS).

Results
Eight of ten patients (5 males, 3 females; 80%) had follow-ups 37 ± 14 months postoperatively. The mean age was 32.4 ± 11.6 years and the mean operation time was 53 ± 21 min. Clinical examination showed a CMS of 91.9 ± 7.9 points (pt), a TF of 10.5 ± 1.1 pt, and an NCS of 76.5 ± 15.3 pt. The VAS score was 0.7 ± 1.5 pt with an average SSV of 83.1 ± 13.4 pt and an ASES of 87.0 ± 12.5 pt. In three cases (37.5%) a concomitant intra-articular pathology was found. Radiological analysis showed a preoperative CC distance of 19.7 ± 3.3 mm, a postoperative distance of 6.9 ± 3.0 mm and 12.0 ± 4.9 mm at follow-up. The clavicular drill hole widened from 3.0 ± 0.4 mm postoperatively to 6.0 ± 1.5 mm at follow-up; 50% of cases had radiological signs of bony non-union, two of which were symptomatic and received revision surgery.

Conclusion
The solely arthroscopic double-button technique shows good clinical results. Although not symptomatic in all cases, the non-union rate is quite high. Thus, this technique should be reserved for special cases with small lateral fragments where anchoring techniques are not an option.
Stand und Herausforderungen der Aussagepsychologie
Authors: Steller Max 
Published: March 2020

ZusammenfassungIn der jüngeren Vergangenheit ist vermehrt Kritik am Einsatz von Glaubhaftigkeitsbegutachtungen in Verfahren zu Sexualdelikten formuliert worden. Ein Tenor dieser Kritik lautet, dass die wissenschaftlichen Grundlagen der Aussagepsychologie für ihren praktischen Einsatz bei einigen relevanten Fragestellungen für Glaubhaftigkeitsbeurteilungen nicht ausreichend seien. Diese nichtfundierte Kritik stellt keine Herausforderung für die Aussagepsychologie dar, wie der vorliegende Beitrag deutlich macht. Herausforderungen ergeben sich aber aus Gesetzesänderungen in der jüngeren Vergangenheit, wie der Verlängerung von Verjährungsfristen bei sexuellem Kindesmissbrauch oder der Sexualstrafrechtsreform, §177 StGB n.F. Trotz dieser Herausforderungen bringen aussagepsychologische Begutachtungen wissenschaftliche Erkenntnisse in Strafprozesse ein und erfahren in der deutschen Gerichtspraxis eine hohe Akzeptanz. In der Mehrzahl der Fälle leisten Glaubhaftigkeitsbegutachtungen einen Beitrag dazu, dass tatsächlichen Opfern ihr Vorbringen geglaubt wird.
Heat recovery from sulfuric acid plants for seawater desalination using RO and MED systems
Authors: Saifaoui D. , Nachtane M. , Tarfaoui M. , Rouway M. , Aroussy Y. 
Published: March 2020

AbstractConforming to the factor characteristics of electricity–water cogeneration power plants, an improved multieffect desalination (MED) and reverse osmosis (RO) are the most current techniques for seawater desalination. A principal change between these operations consists of their various energy requirements, thermal energy for MED and mechanical energy for RO plants. The main improvement ideas of RO and MED are the recovery of large quantities of heat produced during the production of sulfuric acid, which exhibits an exothermic reaction where a part of this heat will be used for the thermal power plant and subsequently reverse osmosis and another amount of heat recovery system will be used to desalinate seawater by the MED system. In this work, the sulfuric acid is used to recover heat energy; this energy is used in a hybrid system of RO–MED in order to desalinate the seawater. A thermodynamic steady-state study of this system is investigated to select the optimum cogeneration system. These improvements could make the benefits of cogeneration to the energy consumption of an RO and MED which will be remarkably reduced.
Unusual dermatomycoses caused by Nannizzia nana: the geophilic origin of human infections
Authors: Gnat Sebastian , Łagowski Dominik , Nowakiewicz Aneta , Dyląg Mariusz 
Published: March 2020

Abstract
Background
Fungal infections of the skin, hair, and nails are the largest and most widespread group of all mycoses. Nannizzia nana is a relatively rare etiological factor of dermatomycosis in humans, as it usually affects animals, e.g. pigs and boars. In addition to the zoophilic nature, there are also reports of the geophilic reservoir of this dermatophyte species.

Objective
In this study, we present symptomatic infections with N. nana aetiology in humans reported recently in Poland. Interestingly, these cases had a non-specific clinical picture and occurred as skin lesions on the neck and foot as well as onychomycosis of the toenails. From the medical history, the patients had no contact with pigs.

Methods
Diagnostics of these infections was performed with a combination of classical phenotypic and molecular genomic methods. The genomic diversity of the isolates was determined using the MP-PCR method. In vitro antifungal susceptibility tests against itraconazole, ketoconazole, terbinafine and naftifine hydrochloride were also performed.

Results
Nannizzia nana has been identified as an etiological factor of dermatomycosis. Moreover, heterogeneity of the genomes was revealed for the obtained strains. In vitro activities of antifungal agents showed that isolates were susceptible to all tested drugs. The patients were treated with oral terbinafine and topical ketoconazole cream, which led to a complete recovery.

Conclusions
In conclusion, the cases studied by us may indicate that the infrequency of N. nana infections may not necessarily be related to the low infectivity of this fungal agent, but they are rather associated with misdiagnosis. Furthermore, N. nana reservoirs should also be sought in soil.