bluuebunny/crossref_metadata_2025_split huggingface dataset:
The development of the Agricultural Producer Barriers to Care Scale (APBCS)
Authors: Hopkins Noah , Reece Chase , Hansen Nathan , Proctor Christina 
Published: December 2024

AbstractPurposeThe purpose of this study was to identify and test the factor structure of the Agricultural Producer Barriers to Care Scale (APBCS), which assesses barriers to engaging with health care in rural US farmers.MethodsRespondents (n = 1045) completed an online survey that was distributed digitally and in‐person by researchers and community partners at farming events and via farm‐related social media. Exploratory and Confirmatory Factor Analysis were used to assess the underlying factor structure of the APBCS, and McDonald's omega coefficients were calculated to test the reliability of each factor and the instrument as a whole. Data analysis was conducted in SPSS 28.0 and MPlus Version 7.4.FindingsThe exploratory factor analysis (n = 689) indicated a four‐factor structure for the APBCS with domains of (i) formal health care challenges, (ii) cultural barriers to help‐seeking, (iii) stigma, and (iv) resilience, which explained 38.408% of the overall variance. The confirmatory factor analysis (n = 231) found that a three‐factor structure, where questions from “cultural barriers to help seeking” were applied to factors for stigma and resilience, was a better fit for the model than the four‐factor model hypothesized by the EFA. The final APBCS showed reliability within each domain, and across the full three‐factor scale.ConclusionThe APBCS is a promising tool that shows high internal consistency and could inform researchers and practitioners about the structural and cultural barriers to engaging with health care in agricultural producers living in the United States.
Diabetes and cardiovascular disease in older adults
Authors: Bilal Anika , Pratley Richard 
Published: December 2024

AbstractAn aging population combined with a rapidly increasing prevalence of diabetes foreshadows a global epidemic of cardiovascular and kidney disease that threatens to halt improvements in life and health‐span and will have particularly severe consequences in older adults. The management of diabetes has been transformed with the recent development of newer anti‐hyperglycemic agents that have demonstrated superior efficacy. However, the utility of these drugs extends beyond glycemic control to benefits for managing obesity, cardiovascular disease (CVD), chronic kidney disease, and heart failure. Numerous cardiovascular and kidney outcomes trials of these drugs have played an instrumental role in shaping current guidelines for the management of diabetes and CVD. Older adults with diabetes are diverse in terms of their comorbidities, diabetic complications, and cognitive and functional status. Therefore, there is an unmet need for personalized management of diabetes and CVD in this population. In this review, we provide an overview of the epidemiological burden and management of diabetes and CVD in older adults. We then focus on randomized cardiovascular and kidney outcome trials with anti‐hyperglycemic agents to propose an evidence‐based approach to the management of diabetes in older adults with high risk of cardiovascular and kidney disease.
How Deep Are the Roots of Female Empowerment? Population Diversity and Gender Inequality*
Authors: Vu Trung V. 
Published: December 2024

AbstractI study the impact of population diversity, determined predominantly over the prehistorical out‐of‐Africa migration process of anatomically modern humans, on present‐day gender inequality. Leveraging variations across countries and individuals residing in the same country but descending from different prehistorically indigenous ethnic groups, I find that deep‐rooted population diversity negatively affects women's economic and political empowerment. I provide several explanations for this finding. First, preindustrial societies with higher interpersonal diversity tended to experience early technological development, which primarily translated into fertility growth associated with lower women's social status during the Malthusian epoch. Second, population diversity was conducive to economic specialization, which co‐evolved with and amplified the traditional gendered division of labour particularly in preindustrial societies with long agricultural histories. Finally, the early formation and prevalence of unequal gender roles in preindustrial times would gradually increase intergenerationally transmitted cultural beliefs about gender inequality, leading to wide and persistent disparities in gender roles across the contemporary world.
Strategizing Simultaneous Spinal Osteotomy and Total Hip Replacement in Ankylosing Spondylitis
Authors: Guo Chen , Liang Yan , Zhu Zhenqi , Xu Shuai , Liu Haiying 
Published: December 2024

ObjectiveAnkylosing spondylitis (AS) is a debilitating rheumatic condition that significantly impairs mobility and quality of life through chronic inflammation and spinal fusion. The aim of this study is to investigate the optimal sequencing of spinal osteotomy and total hip replacement (THR) as treatment options, a topic that remains a subject of debate among medical professionals.MethodsIn a retrospective cohort study spanning from 2017 to 2021, we assessed adult patients with AS who underwent both spinal osteotomy and THR, outcome measures involved radiographic assessments like Global Cobb angle, thoracolumbar kyphosis (TLK), lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT), and sacral slope (SS), as well as clinical metrics such as the Harris hip score. For the same surgical group, paired t‐tests were performed for pre‐ and postoperative data, while independent sample t‐tests were used for comparing different surgical groups. The study aims to elucidate the optimal sequencing of these surgical procedures based on these comprehensive metrics.ResultsAmong the 14 patients included, demographic and clinical variables were comparable between the two procedural groups. At the 3‐month follow‐up, all major metrics showed significant postoperative improvements. Specifically, the Global Cobb angle reduced from 98.88 ± 38.54 to 54.48 ± 18.14 (p = 0.018), and the Harris hip scores, evaluated at the 3‐month follow‐up, dramatically increased from 15.14 ± 10.12 to 72.57 ± 14.12 (p = 0.001). Furthermore, the Spine First Group exhibited more pronounced changes in pelvic parameters (p = 0.009), albeit at the expense of longer operation times and increased blood loss. No major complications were encountered.ConclusionsContrary to the prevalent belief that spinal osteotomy should precede THR, our study argues that under certain conditions, opting for hip surgery first can be both viable and advantageous. This approach may mitigate the risk of complications and even facilitate subsequent spinal surgery. Surgical decisions must be highly tailored, focusing on patient‐specific needs and anatomical considerations. The ultimate goal remains consistent: to improve patients' functional abilities in daily activities and thereby enhance their overall quality of life.
Rational design of azo‐aminopyrimidine derivatives as the potent lepidoptera‐exclusive chitinase inhibitors
Authors: Ding Baokang , Ma Shujie , Yang Meiling , Zhang Quanguo , Hua Xiujia , Zhang Jiahao , Bai Shenmeng , Zhang Lihui , Dong Jingao , Shen Shengqiang , Dong Lili 
Published: December 2024

SummaryOstrinia furnacalis (O. furnacalis) is a commonly occurring agricultural pest that can severely impact corn yield and quality. Therefore, establishing and implementing effective control methods against O. furnacalis are of great significance. Chemical insecticides remain the most effective means to mitigate the damage caused by O. furnacalis. With the increasing resistance of O. furnacalis to insecticides, it is imperative to identify and develop compounds with novel mechanisms of action and high safety. The chitinase OfChi‐h, identified and characterized in O. furnacalis, has been recognized as a potential insecticide target. In this study, a series of azo‐aminopyrimidine analogues were synthesized as OfChi‐h inhibitors employing rational molecular optimization. Among them, compounds 9b, 10a and 10g exhibited Ki values of 23.2, 19.4, and 43.2 nM against OfChi‐h, respectively. Molecular docking studies were carried out to explore the molecular basis for the high efficacy of these compounds and OfChi‐h. In addition, the morphological changes of the cuticle in inhibitor‐treated O. furnacalis larvae were assessed using scanning electron microscopy. Furthermore, the target compounds were assayed in leaf dipping and pot experiments, with compound 10a exhibiting greater insecticidal activity against Plutella xylostella (P. xylostella) and O. furnacalis than diflubenzuron and chlorbenzuron. At the same time, the toxicity of these compounds to natural enemies Trichogramma ostriniae and rats was negligible. The present study demonstrates that the azo‐aminopyrimidine skeleton can be used as a novel, low‐cost scaffold for developing insect chitinolytic enzyme inhibitors, with the potential to be utilized as new environmentally friendly insecticides.
Colletotrichum nymphaeae and Colletotrichum theobromicola isolated from anthracnose symptoms cause grape ripe rot
Authors: Steiner Daniel Ricardo Maass , Modesto Lenon Romano , Dias Andressa Hilha , Zappelini Júlia , Petters‐Vandresen Desirrê Alexia Lourenço , Castellar Camilla , De Mio Louise Larissa May , Nodari Rubens Onofre 
Published: December 2024

AbstractColletotrichum species are the causal agents of grape ripe rot (GRR). However, Colletotrichum isolates have been isolated from symptoms of leaf grape anthracnose (GA) caused by Elsinöe ampelina infection. Thus, the present study aimed to evaluate whether Colletotrichum isolates obtained from grapes with GA are pathogenic on grapevine leaf, cane, or berry causing GA, or if they can cause GRR symptoms on ripe grapes. Colletotrichum isolates were characterized by genetic and morphological analyses as well as pathogenicity tests. One isolate of E. ampelina from GA and one of Colletotrichum acutatum complex (GL1) collected from GRR symptoms were used as reference isolates. Colletotrichum isolates from GA lesions were identified by genetic and morphological differences as C. nymphaeae (17 isolates) and C. theobromicola (one isolate). C. theobromicola was found for the first time associated with grapes in Brazil. C. nymphaeae and C. theobromicola did not cause lesions on grapevine leaf or cane, but the isolate of E. ampelina confirmed symptoms of typical GA. The Colletotrichum isolates from leaves were pathogenic on grapevine berries leading to GRR symptoms. Epidemiological studies on the relevance of Colletotrichum latent infection on leaves as a source of primary inoculum of ripe rot and the interference of co‐infections of E. ampelina × Colletotrichum spp. on GA symptoms should be further investigated.
Searching for Higher Ground: Watershed Migration and Cultural Curation in the Fallout of Disaster*
Authors: Folse Brandon , Theis Nicholas , Shtob Daniel 
Published: December 2024

AbstractDue to land loss from sea level rise, subsidence, and hurricanes, coastal Louisiana residents face decisions about whether and how to move to live more securely. These (seemingly) biophysical processes are compounded by sociocultural evolution and technological progress, which often make rural people and communities feel devalued. Using these observations as a background, we ask: how do disaster‐related migration strategies correspond to broader migration trends nationally and globally? And, how do local, place‐based cultures influence and permeate these migration decisions and strategies? We rely on 32 interviews with those who are from southeastern Louisiana and are connected to local seafood industries. Using the Intracoastal Canal as a line of risk demarcation, respondents were recruited as either stayers (those residing south of the canal) or migrants (those who moved north of the canal or elsewhere). We find that within both groups, many individuals and/or their family members participate in watershed migration and cultural curation, practices of moving up the bayou toward safer ground and bringing place‐based practices along with this movement. We conclude by highlighting how the non‐linear experiences of migrants are part of larger historical narratives and practices of change, migration, and cultural and physical survival.
Description of the Novel Allele HLA‐B*44:418, Identified in a Bone Marrow Donor
Authors: Cheranev Valery , Syrko Denis , Jankevic Tatiana , Loginova Maria , Korostin Dmitry 
Published: December 2024

ABSTRACTThe new HLA‐B*44:418 allele showed one non‐synonymous nucleotide difference compared with the HLA‐B*44:05:01:01 allele in codon 12.
Viability of Plasmodium falciparum parasites in human plasma under different storage conditions
Authors: Lavrentieva Anna , Oakley Miranda S. , Hayashi Clifford T. H. , Majam Victoria F. , Eder Anne F. , Villa Carlos H. , Kumar Sanjai 
Published: December 2024

AbstractBackground and ObjectivesMalaria risk deferral policies are important for mitigating the risk of transfusion‐transmitted malaria and apply to all transfusable components, including plasma. While donors of plasma components are deferred for malaria risk in the United States, the viability of intraerythrocytic Plasmodium falciparum parasites present in human plasma components stored under different temperatures and durations has not been previously reported.Materials and MethodsWe spiked human plasma with a low level of ring‐stage P. falciparum‐infected red blood cells and then determined their viability in cultures after storage at room temperature (22°C), refrigeration (4°C) and frozen conditions at −20 and −80°C.ResultsP. falciparum parasites spiked in human plasma remained viable after storage at 22°C for a maximum of 7 days. When stored at 4°C, parasites were viable after 1 and 3 days of storage and only for 1 day after storage at −20°C. Storage at −80°C had a cryopreserving effect and parasites remained viable for up to 176 days, the longest period tested.ConclusionP. falciparum parasites can survive for short durations in human plasma when stored at room temperature, or in refrigerated or frozen conditions at −20°C. However, when stored at −80°C, viable parasites were detected for up to 176 days, the maximum duration for which viability was assessed. In summary, Plasmodium parasites can survive in human plasma under different storage conditions and pose a risk of transfusion‐transmitted infection.
Global solutions for semilinear parabolic evolution problems with Hölder continuous nonlinearities
Authors: Matioc Bogdan‐Vasile , Walker Christoph 
Published: December 2024

AbstractIt is shown that semilinear parabolic evolution equations featuring Hölder continuous nonlinearities with at most linear growth possess global strong solutions for a general class of initial data. The abstract results are applied to a recent model describing front propagation in bushfires and in the context of a reaction–diffusion system.
Evaluation of Irregular Motion in Endovascular Treatment
Authors: Kobayashi Kengo , Takashima Kazuto , Toma Naoki , Mori Koji 
Published: December 2024

Abstract
Vascular intervention using guidewires and catheters has been widely performed, but the selection of appropriate device manipulation is often based on the experience and skills of the surgeon. Occasionally, accidents occur due to unexpected movements of these device tips, resulting in vascular damage. To address the challenge of unpredictable device motions and the associated risk of vessel wall damage, this study aims to investigate how different vessel shapes influence device motions. Additionally, we seek to identify effective manipulation techniques to mitigate these risks. We conducted experiments involving the insertion of a guidewire and a catheter into crank-shaped blood vessel phantom models with three different bending angles. Throughout the experiment, the movement of the inserted guidewire within the blood vessel phantoms was recorded using video recording. It was discovered that jumping distance and number of jumps increased as the distance between the catheter and guidewire tip increased. In experiments with a small bending angle, guidewire jumping was infrequent, but when it occurred, jumps tended to be longer (4.0 ± 2.4 mm). Conversely, experiments involving large bending angles showed short consecutive jumps, with the last jumping distance typically being a relatively longer (2.5 ± 1.3 mm). These findings indicate that irregular motions can be reduced by keeping a catheter close to a guidewire tip. Moreover, when the bending angle is large, a manipulator should be ready to prevent further motions as soon as they notice a small first jump.
Exploiting Stochastic Resonance Principles to Influence the Efficiency of a Torsional-Flutter Energy Harvester in Turbulent Winds
Authors: Caracoglia Luca 
Published: December 2024

Abstract
Wind energy harvesters are emerging as a viable alternative to standard, large horizontal-axis wind turbines. This study continues a recent investigation on the operational features of a torsional-flutter-based apparatus, proposed by the author to extract wind energy. The apparatus is composed of a non-deformable, flapping blade-airfoil. A nonlinear torsional spring mechanism, either simulated by a Duffing model or a hybrid Duffing–van der Pol model, installed at equally spaced supports, enables limit-cycle, post-critical vibration. To enhance the output power, stochastic resonance principles are invoked through a novel, negative stiffness mechanism that is coupled to the eddy current device for energy conversion. The output power is explored by numerically solving the stochastic differential equation of the model, accounting for incoming flow turbulence. Three main harvester types with variable configuration are examined; the chord length of the blade-airfoil, used for energy harvesting, varies between 0.5 and 1 m; the spanwise-length-to-chord aspect ratio is four. The flapping frequency varies between 0.10 and 0.25 Hz. The study demonstrates that exploitation of negative stiffness mechanism can improve the performance of the harvester.
Does Annulus Fibrosus Lamellar Adhesion Testing Require Preconditioning?
Authors: Sinopoli Sabrina I. , Whittal Mitchel C. , Briar K. Josh , Gregory Diane E. 
Published: December 2024

Abstract
The interlamellar matrix (ILM), located between the annular layers of the intervertebral disc (IVD), is an adhesive component which acts to resist delamination. Investigating the mechanical properties of the ILM can provide us with valuable information regarding risk of disc injury; however given its viscoelastic nature, it may be necessary to conduct preconditioning on tissue samples before measuring these ILM properties. Therefore, the aim of this study was to optimize mechanical testing protocols of the ILM by examining the effect of preconditioning on stiffness and strength of this adhesive matrix. Eighty-eight annular samples were dissected from 22 porcine cervical discs and randomized into one of four testing conditions consisting of ten cycles of 15% strain followed by a 180 deg adhesive peel test. The four testing groups employed a different strain rate for the ten cycles of preconditioning: 0.01 mm/s (n = 23); 0.1 mm/s (n = 26); 1 mm/s (n = 23); and no preconditioning employed (n = 16). Samples preconditioned at 0.01 mm/s were significantly less stiff than those that had not received preconditioning (p = 0.014). No other results were found to be statistically significant. Given the lack of differences observed in this study, preconditioning is likely not necessary prior to conducting a 180 deg peel test. However, if preconditioning is employed, the findings from this study suggest avoiding preconditioning conducted at very slow rates (i.e., 0.01 mm/s) as the long testing time may negatively affect the tissue.
Experimental Investigation on the Dynamic Response of a Turbocharger Centrifugal Compressor in Surge Transitions
Authors: Silvestri Paolo , Marelli Silvia , Usai Vittorio 
Published: December 2024

Abstract
Centrifugal compressors play a critical role in various industrial applications, and understanding their operational behavior, especially during surge conditions, is essential for enhancing efficiency and reliability. This study investigates surge transitions in centrifugal compressors by employing a comprehensive approach that integrates dynamic mass flow rate and pressure measurements together with dynamic structural response data. To gain insight into the transition from the stable to the unstable region of the compressor, an extensive experimental analysis on a centrifugal compressor was conducted. The activity involves measurements used to characterize and identify the behavior of the compressor in correspondence of surge inception conditions. Frequency and time–frequency data analysis techniques have been employed to examine the inflow pressure and the anemometric signal. The purpose is to identify their characteristics and define the compressor operation as stable or unstable. Synchronous averages, applied in the time domain, have proven to be effective for detecting incipient surge conditions. Additionally, statistical techniques, such as variance and spectral kurtosis (SK), have been utilized for the detection in signals with strong additive noise and nondeterministic contents. A method for system identification in deep surge is introduced, particularly focusing on the correlation between the compressor circuit geometries and the operating conditions of the turbocharger. This approach enhances the diagnostic capability of the monitoring system by providing a better knowledge of surge occurrence. The paper is aimed to provide information for the development of control strategies and predictive maintenance protocols to mitigate surge-related issues.
The Tribocorrosion Resistance of Posttreated Supersonic Plasma-Sprayed MoSi2 Coating
Authors: Hu Chunhua , Guo Quanqiang , Ji Xinghao , Liu Yu 
Published: December 2024

Abstract
MoSi2 coatings were prepared on a 45CrNi substrate by supersonic plasma spraying (SAPS). The tribocorrosion resistance of MoSi2 coating and posttreated MoSi2 coating (P-MoSi2) in the seawater environment was analyzed. After posttreatment, some new phases such as MoO3, SiO2, and Mo9O26 are generated in the P-MoSi2 coating. The electrochemical test results indicated that the P-MoSi2 coating has lower current density and larger −βc and Rp values than MoSi2 coating in both static corrosion and tribocorrosion tests. The wear test results indicated that the posttreatment reduces the wear-rate and friction coefficient of the coating. The wear mechanisms of both coatings were described to explain the differences. Also, the mechanism of the improved tribocorrosion resistance after posttreatment was explained.