bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Dynamic Chemical Etching on the Pore Structure, Permeability, and Mechanical Properties of Ti-Nb-Zr Scaffolds for Medical Applications
Authors: Sheremetyev V. , Dubinskiy S. , Iqbal M. A. , Lukashevich K. , Prokoshkin S. , Brailovski V. 
Published: September 2020

Abstract
Improving the post-processing of metallic porous tissue scaffolds is an essential step to create a new generation of superelastic implants for the replacement of damaged bone tissue. In this study, the dynamic chemical etching technique is applied to improve the permeability and to optimize the porous structure of Ti-Nb-Zr scaffolds fabricated by the powder metallurgy-based space holder technique. The etched scaffolds are characterized in terms of their porous structure geometry, permeability, and mechanical properties. It is shown that an increase in porosity from 49% to 54% during the etching is mainly due to an increase in the number of 100 to 800 μm-diameter pores, from 30% to 50% of them measuring from 100 to 300 μm in size. These changes in the porous structure lead to a significant increase of its permeability, i.e., from (0.1–15) × 10−11 m2 before etching to (44–91) × 10−11 m2, after etching; these permeability ranges corresponding to those of bone tissues. Furthermore, the etched scaffolds show systematically higher yield compressive stresses as compared to the as-sintered scaffolds of equivalent porosities. Finally, the highly permeable etched Ti-Nb-Zr scaffolds with a porosity varying from 40% to 60% exhibit an apparent Young’s modulus ranging from 8.6 to 1.9 GPa and an ultimate compressive strength from 650 to 190 MPa, which can be considered as a promising balance of properties for the potential use of these scaffolds as bone implants.
Effect of Process Parameters on Wavy Interfacial Morphology During Magnetic Pulse Welding
Authors: Zhang Shunyi , Lueg-Althoff Joern , Hahn Marlon , Tekkaya A. Erman , Kinsey Brad 
Published: September 2020

Abstract
Magnetic pulse welding (MPW) is a solid-state welding process that bonds similar and dissimilar metals using a high velocity collision. In this paper, effects of impact velocity, target tube thickness, and mandrel inclusion on the interfacial morphology were investigated through the welding of tubular parts, Al6060T4 (flyer) to Cu-ETP (target), by electromagnetic compression. The hypothesis tested in this research is that a “well-supported target,” i.e., either a thick target or the support of a mandrel, allows for vortices to be created at the interface during MPW provided that the impact velocity is sufficient. The mandrel used in the experiments was polyurethane with a Shore hardness of 92A, which was pre-stressed via a washer and nut. The impact velocity was measured via photon Doppler velocimetry (PDV) and used for the setup of numerical simulations. A 2D axisymmetric numerical model was implemented in LS-DYNA to predict the interfacial morphology. Thermal analyses in the numerical model were used to predict the local melting locations and compared with experimental observations. Both experimental and numerical results showed that the interfacial wavelength increased with an increase in the impact velocity and target thickness. Similarly, a thin target with mandrel support also caused an increase in the wavelength. Vortices were only generated with appropriate impact velocities and well-supported targets, i.e., again either a thick target or the support of a mandrel.
Syngas Generation From Landfills Derived Torrefied Refuse Fuel Using a Downdraft Gasifier
Authors: Laohalidanond Krongkaew , Kerdsuwan Somrat , Burra Kiran Raj Goud , Li Jinhu , Gupta Ashwani K. 
Published: September 2020

AbstractLandfill reclamation is a good solution to utilize the wasted land occupied by municipal solid waste dumpsites or landfill sites. This also offers a good means to recover valuable materials and form environmentally benign green refuse-derived fuel (RDF) for use in power production. However, due to the heterogenous composition of the wastes, it is crucial to homogenize and upgrade the waste hydrocarbon fuel properties. Torrefaction is a thermochemical process that utilizes low temperature and inert environment to drive off the moisture and volatile fractions present in wastes to form valuable fuel. This upgraded RDF from reclaimed landfills offer high energy density and favorable hydrophobicity for use as a fuel feedstock in gasification to produce syngas for power generation. The objectives of this study are to first upgrading the reclaimed landfill wastes to RDF using torrefaction followed by its conversion to form clean syngas in a downdraft gasifier. This study examines the effect of air ratio on syngas heating value and cold gas efficiency. A comparison is made on the syngas produced from gasification using reclaimed landfill wastes and torrefied RDF. Experiments were conducted using a 10 kg/h lab-scale downdraft gasifier. The air ratios examined were 0.22, 0.27, and 0.32. The results showed an optimum air ratio of 0.27 operated with a gasifier using torrefied RDF. The results showed improved syngas quality, in terms of syngas composition, lower heating value, and cold gas efficiency. The lower heating value of 4.22 MJ/Nm3 and the cold gas efficiency of 65.84% were achieved. The results showed that landfill mining can provide ultimate solution to get rid of dumped wastes from landfills using torrefaction for high-quality fuel followed by the recovery of green and clean syngas energy using gasification.
The formation of continental roots
Authors: Priestley Keith , Ho Tak , McKenzie Dan 
Published: September 2020

AbstractNew evidence from seismic tomography reveals a unique mineral fabric restricted to the thick mantle lithosphere beneath ancient continental cratons, providing an important clue to the formation of these prominent and influential features in Earth’s geological history. Olivine, the dominant mineral of Earth’s upper mantle, has elastic properties that differ along its three crystallographic axes, and preferential alignment of individual olivine grains during plastic deformation can affect the bulk nature of seismic-wave propagation. Surface-wave tomography has shown that over most of Earth, deformation of the mantle lithosphere has oriented olivine crystals with the fast axis in the horizontal plane, but at depths centered at ∼150 km within cratonic continental-lithosphere roots, the fast crystallographic axis is preferentially aligned vertically. Because of the high viscosity of the cratonic roots, this fabric is likely to be a vestige from craton formation. Geochemical and petrological studies of upper-mantle garnet-peridotite nodules demonstrate that the cratonic mantle roots are stabilized by their reduced density, which was caused by melt removal at much shallower depths than those from which the nodules were subsequently extracted. The mineral fabric inferred from surface-wave tomography suggests that horizontal shortening carried the depleted zone downward after the melt-depletion event to form the thick continental roots, stretching the depleted material in the vertical dimension by pure shear and causing the fast crystallographic axis to be aligned vertically. This seismological fabric at ∼150 km is evidence of the shortening event that created the cratonic roots.
Association of physical activity with all-cause and cardiovascular mortality in 7666 adults with hypertrophic cardiomyopathy (HCM): more physical activity is better
Authors: Kwon Soonil , Lee Hyun-Jung , Han Kyung-Do , Kim Da Hye , Lee Seung-Pyo , Hwang In-Chang , Yoon Yeonyee , Park Jun-Bean , Lee Heesun , Kwak Soongu , Yang Seokhun , Cho Goo-Yeong , Kim Yong-Jin , Kim Hyung-Kwan , Ommen Steve R 
Published: September 2020

ObjectivesRecommendations on physical activity (PA) for adults with hypertrophic cardiomyopathy (HCM) are not well established. We investigated the association of PA intensity with mortality in the general adult HCM population.MethodsA nationwide population-based cohort of individuals with HCM who underwent health check-ups including questionnaires on PA levels were identified from the years 2009 to 2016 in the National Health Insurance Service database. Subjects who reported no PA at baseline were excluded. To estimate each individual’s PA level, the PA score (PAS) was calculated based on the self-reported questionnaires, and the study population was categorised into three groups according to tertiles of PAS. The associations of PAS with all-cause and cardiovascular mortality were analysed.ResultsA total of 7666 participants (mean age 59.5 years, 29.9% were women) were followed up for a mean 5.3±2.0 years. All-cause and cardiovascular mortality progressively decreased from the lowest to the highest tertiles of PA intensity: 9.1% (4.7%), 8.9% (3.8%) and 6.4% (2.7%), respectively (p-for-trend=0.0144 and 0.0023, respectively). Of note, compared with the middle PA group, the highest PA group did not have an increased risk of all-cause and cardiovascular mortality (HR 0.78, (95% CI 0.63 to 0.95) and HR 0.75 (95% CI 0.54 to 1.03), respectively). All subgroup and sensitivity analyses consistently showed that all-cause and cardiovascular mortality did not increase with higher PA levels.ConclusionsModerate-to-vigorous-intensity PA, in a middle-aged population of patients with HCM, was associated with progressive reduction of all-cause and cardiovascular mortality. The impact of vigorous-intensity PA on a younger age group requires further investigation.
Adherence to dietary and physical activity guidelines among shift workers: associations with individual and work-related factors
Authors: Kelly Ciara , Nea Fiona M , Pourshahidi L Kirsty , Kearney John M , O'Brien Victoria , Livingstone M Barbara E , Corish Clare A 
Published: September 2020

ObjectivesShift work is associated with adverse effects on the health and lifestyle behaviours of employees. This study aimed to examine factors associated with adherence among shift workers to selected indicators of dietary and physical activity guidelines.MethodsA cross-sectional study was conducted on 1300 shift workers. Data were collected using a 15 minute telephone-administered questionnaire. Logistic regression methods were used for data analysis.ResultsMale shift workers (p<0.001, OR=0.55, 95% CI 0.40 to 0.74) and those of lower socioeconomic status (p=0.046, OR=0.75, 95% CI 0.57 to 0.99) were significantly less likely to consume five or more daily servings of fruits and vegetables. Shift workers with access to workplace vending machines were significantly more likely to consume soft drinks at least weekly (p=0.003, OR=1.64, 95% CI 1.18 to 2.27). Middle-aged shift workers (p=0.012, OR=0.65, 95% CI 0.46 to 0.91) and those reporting insufficient break times at work (p=0.026, OR=0.69, 95% CI 0.49 to 0.96) were significantly less likely to be sufficiently active.ConclusionsIndividual, work schedule and workplace environment related factors were independently associated with selected indicators of adherence to dietary and physical activity guidelines in this cohort of shift workers.
Study for Improving Maternal Pregnancy And Child ouTcomes (IMPACT): a study protocol for a Swedish prospective multicentre cohort study
Authors: Bergman Lina , Sandström Anna , Jacobsson Bo , Hansson Stefan , Lindgren Peter , Larsson Anders , Imberg Henrik , Conner Peter , Kublickas Marius , Carlsson Ylva , Wikström Anna-Karin 
Published: September 2020

IntroductionFirst-trimester pregnancy risk evaluation facilitates individualised antenatal care, as well as application of preventive strategies for pre-eclampsia or birth of a small for gestational age infant. A range of early intervention strategies in pregnancies identified as high risk at the end of the first trimester has been shown to decrease the risk of preterm pre-eclampsia (<37 gestational weeks). The aim of this project is to create the Improving Maternal Pregnancy And Child ouTcomes (IMPACT) database; a nationwide database with individual patient data, including predictors recorded at the end of the first trimester and later pregnancy outcomes, to identify women at high risk of pre-eclampsia. A second aim is to link the IMPACT database to a biobank with first-trimester blood samples.Methods and analysisThis is a Swedish prospective multicentre cohort study. Women are included between the 11th and 14th weeks of pregnancy. At inclusion, pre-identified predictors are retrieved by interviews and medical examinations. Blood samples are collected and stored in a biobank. Additional predictors and pregnancy outcomes are retrieved from the Swedish Pregnancy Register. Inclusion in the study began in November 2018 with a targeted sample size of 45 000 pregnancies by end of 2021. Creation of a new risk prediction model will then be developed, validated and implemented. The database and biobank will enable future research on prediction of various pregnancy-related complications.Ethics and disseminationConfidentiality aspects such as data encryption and storage comply with the General Data Protection Regulation and with ethical committee requirements. This study has been granted national ethical approval by the Swedish Ethical Review Authority (Uppsala 2018-231) and national biobank approval at Uppsala Biobank (18237 2 2018 231). Results from the current as well as future studies using information from the IMPACT database will be published in peer-reviewed journals.Trial registration numberNCT03831490.
Anaemia prevalence in children newly registered at UNRWA schools: a cross-sectional study
Authors: AbuKishk Nada , Turki Yassir , Saleh Suha , Albaik Shatha , Hababeh Majed , el-Khatib Zoheir , Kassim Nimer , Arab Hasan , Abu-Diab Khawalah , Zeidan Wafaa , Seita Akihiro 
Published: September 2020

ObjectiveChildren entering first grade at the United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) schools in West Bank, Gaza, Lebanon, Jordan and Syria complete a comprehensive medical examination at UNRWA health centres (HCs) as a requirement for their acceptance. Our study aimed to assess anaemia prevalence and undernutrition indicators among new entrant school children during their preschool medical examination.SettingsIn 2017, we conducted a cross-sectional study in 59 UNRWA HCs, targeting children entering first grade at UNRWA schools in four of UNRWA’s countries of operation (known as fields), namely Gaza, West Bank, Syria and Lebanon.Participants2419 completed the study. Boys and girls living inside or outside Palestine refugee camps were included. Verbal consent was obtained from their parents.Primary and secondary outcome measuresSociodemographic and anthropometric data on each child were collected. Underweight (weight-for-age z-score <−2 SD), stunting (height-for-age z-score <−2 SD), thinness (body mass index-for-age z-score <−2 SD) and obesity (body mass index-for-age z-score >+2 SD) were examined according to WHO growth indicators (5–10 years).Results2419 students (1278 girls and 1141 boys) aged 6.1±0.4 years were examined. The prevalence of anaemia (haemoglobin (Hb) <11.5 g/L) was 25.0% (Gaza: 29.3%; West Bank: 22.0%; Syria: 30.0%; Lebanon: 18.3%). The mean Hb level was 12.0±0.9 g/L. The overall prevalence of stunting, thinness and underweight was 3.2%, 3.5% and 5.6%, respectively, with the highest levels found in Syria (4.3%, 6.3% and 10.1%, respectively). The highest prevalence of overweight was in Lebanon (8.6%), and the lowest was in Gaza (2.6%). Significant differences were found among fields with regard to undernutrition indicators (p=0.001). Also, children with anaemia had significantly higher prevalence of being underweight (5.2%) in comparison with those without anaemia (p=0.001).ConclusionsThe prevalence of anaemia among the surveyed children increased to 25.0%, compared with the previous study conducted by UNRWA in 2005 (19.5%). Thus, it is recommended that Hb testing be included in the medical examination of new entrant school children attending UNRWA schools.
The AEDUCATE Collaboration. Comprehensive antenatal education birth preparation programmes to reduce the rates of caesarean section in nulliparous women. Protocol for an individual participant data prospective meta-analysis
Authors: Levett Kate M , Lord Sarah J , Dahlen Hannah G , Smith Caroline A , Girosi Federico , Downe Soo , Finlayson Kenneth William , Fleet Julie , Steen Mary , Davey Mary-Ann , Newnham Elizabeth , Werner Anette , Arnott Leslie , Sutcliffe Kerry , Seidler Anna Lene , Hunter Kylie Elizabeth , Askie Lisa 
Published: September 2020

IntroductionRates of medical interventions in normal labour and birth are increasing. This prospective meta-analysis (PMA) proposes to assess whether the addition of a comprehensive multicomponent birth preparation programme reduces caesarean section (CS) in nulliparous women compared with standard hospital care. Additionally, do participant characteristics, intervention components or hospital characteristics modify the effectiveness of the programme?Methods and analysisPopulation: women with singleton vertex pregnancies, no planned caesarean section (CS) or epidural.Intervention: in addition to hospital-based standard care, a comprehensive antenatal education programme that includes multiple components for birth preparation, addressing the three objectives: preparing women and their birth partner/support person for childbirth through education on physiological/hormonal birth (knowledge and understanding); building women’s confidence through psychological preparation (positive mindset) and support their ability to birth without pain relief using evidence-based tools (tools and techniques). The intervention could occur in a hospital-based or community setting.Comparator: standard care alone in hospital-based maternity units.OutcomesPrimary: CS.Secondary: epidural analgesia, mode of birth, perineal trauma, postpartum haemorrhage, newborn resuscitation, psychosocial well-being.Subgroup analysis: parity, model of care, maternal risk status, maternal education, maternal socio-economic status, intervention components.Study designAn individual participant data (IPD) prospective meta-analysis (PMA) of randomised controlled trials, including cluster design. Each trial is conducted independently but share core protocol elements to contribute data to the PMA. Participating trials are deemed eligible for the PMA if their results are not yet known outside their Data Monitoring Committees.Ethics and disseminationParticipants in the individual trials will consent to participation, with respective trials receiving ethical approval by their local Human Research Ethics Committees. Individual datasets remain the property of trialists, and can be published prior to the publication of final PMA results. The overall data for meta-analysis will be held, analysed and published by the collaborative group, led by the Cochrane PMA group.Trial registration numberCRD42020103857.
Multiprofessional perspectives on the identification of latent safety threats via in situ simulation: a prospective cohort pilot study
Authors: Rusiecki Daniel , Walker Melanie , Douglas Stuart L , Hoffe Sharleen , Chaplin Timothy 
Published: September 2020

ObjectivesTo describe the association between participant profession and the number and type of latent safety threats (LSTs) identified during in situ simulation (ISS). Secondary objectives were to describe the association between both (a) participants’ years of experience and LST identification and (b) type of scenario and number of identified LSTs.MethodsEmergency staff physicians (MDs), registered nurses (RNs) and respiratory therapists (RTs) participated in ISS sessions in the emergency department (ED) of a tertiary care teaching hospital. Adult and paediatric scenarios were designed to be high-acuity, low-occurrence resuscitation cases. Simulations were 10 min in duration. A written survey was administered to participants immediately postsimulation, collecting demographic data and perceived LSTs. Survey data was collated and LSTs were grouped using a previously described framework.ResultsThirteen simulation sessions were completed from July to November 2018, with 59 participants (12 MDs, 41 RNs, 6 RTs). Twenty-four unique LSTs were identified from survey data. RNs identified a median of 2 (IQR 1, 2.5) LSTs, significantly more than RTs (0.5 (IQR 0, 1.25), p=0.04). Within respective professions, MDs and RTs most commonly identified equipment issues, and RNs most commonly identified medication issues. Participants with ≤10 years of experience identified a median of 2 (IQR 1, 3) LSTs versus 1 (IQR 1, 2) LST in those with >10 years of experience (p=0.06). Adult and paediatric patient scenarios were associated with the identification of a median of 4 (IQR 3.0, 4.0) and 5 LSTs (IQR 3.5, 6.5), respectively (p=0.15).ConclusionsInclusion of a multidisciplinary team is important during ISS in order to gain a breadth of perspectives for the identification of LSTs. In our study, participants with ≤10 years of experience and simulations with paediatric scenarios were associated with a higher number of identified LSTs; however, the difference was not statistically significant.
Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales
Authors: Gillespie David , Knapper Carys , Hughes Dyfrig , Couzens Zoe , Wood Fiona , de Bruin Marijn , Ma Richard , Jones Adam Thomas , Williams Adam , Hood Kerenza 
Published: September 2020

Objectives
To describe the early impact of COVID-19 and associated control measures on the sexual behaviour of pre-exposure prophylaxis (PrEP) users in Wales.

Methods
Data were obtained from an ecological momentary assessment study of PrEP use and sexual behaviour. Participants were individuals accessing PrEP through the National Health Service (NHS) sexual health clinics across four health boards in Wales. Weekly data documenting condomless sex in the preceding week were analysed between 03/02/2020 and 10/05/2020. The introduction of social distancing measures and changes to sexual health clinics in Wales occurred on the week starting 16/03/2020. Two-level logistic regression models were fitted to condomless sex (yes/no) over time, included an indicator for the week starting 16/03/2020, and were extended to explore differential associations by relationship status and sexual health clinic.

Results
Data were available from 56 participants and included 697 person-weeks (89% of the maximum number that could have been obtained). On average, 42% of participants reported condomless sex in the period prior to the introduction of social distancing measures and 20% reported condomless sex after (OR=0.16, 95% CI 0.07 to 0.37, p<0.001). There was some evidence to suggest that this association was moderated by relationship status (OR for single participants=0.09, 95% CI 0.06 to 0.23; OR for not single participants=0.46, 95% CI 0.16 to 1.25).

Conclusions
The introduction of social distancing measures and changes to PrEP services across Wales was associated with a marked reduction in reported instances of condomless sexual intercourse among respondents, with a larger reduction in those who were single compared with those who were not. The long-term impact of COVID-19 and associated control measures on this population’s physical and mental health and well-being requires close examination.