bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dentists’ Perception&nbsp;and Clinical use of Preformed Metal Crowns&nbsp;to Restore Primary Molar Defects in Chengdu City, China: A Cross-Sectional Study
Authors: Jiang Qingsong , Wang Yan , Zou Jing , Zhang Qiong 
Published: October 2020

Abstract
Background: Preformed metal crowns (PMCs) are recommended for the enduring restoration of primary molar defects. However, the PMC technique is not implemented in China as well as that in Western countries. Aim: This study aimed to assess the clinical use of the PMC technique and its effective factors among dentists in Chengdu, China.Methods: The questionnaires were distributed among 1000 dentists practicing in Chengdu via an online questionnaire platform. Data, including sociodemographic characteristics of the respondents and their perception and use of PMCs, were collected. Results: The response rate was 45%. Most respondents (69.6%) did not use PMCs. Academic qualification, working specialty and working experiences were associated with dentists’ use of PMCs. The lack of knowledge about PMCs technique was the main obstacle for the dental practitioners using PMCs (41.7%). The lack of understanding of the rationale of PMCs was the main reason for parents accepting PMC restorations(43.6%). Attending continuing education programs was the main approach to learn the PMC restorative technique(59.1%).Conclusion: The clinical use of PMCs was not very popular in Chengdu city. To promote the use of this restorative technique, the knowledge and practical training should be incorporated into routine courses of undergraduate dental education.
Safety of measles, mumps, and rubella vaccine in egg allergy:in vivo and in vitro management
Authors: Magistà Stefania , Albanesi Marcello , Chaoul Nada , Bona Danilo Di , Leo Elisabetta Di , Nettis Eustachio , Caiaffa Maria Filomena , Macchia Luigi 
Published: October 2020

Abstract
Background Egg allergy is the second most prevalent form of food allergy in childhood. In spite of the evidence accumulated, inoculating egg allergy children with attenuated vaccines grown on chick embryo cell cultures, such as the measles, mumps, and rubella (MMR) vaccine, is regarded (erroneously) as potentially dangerous or even anaphylactogenic, by many. An issue perceived as particularly conflicting also by Health Professionals.Case presentation A 15-year-old boy, with a history of severe egg allergy in early infancy, who was still sensitized to egg allergens, including baked egg, had never received MMR vaccination, in fear of possible anaphylaxis, in spite of the fact that this vaccination is mandatory in the first year of life, in Italy. Because of that, he was not allowed to attend school, longer, and was referred to us in order to assess the potential risk of MMR vaccination. Upon thorough allergologic workup, sensitization to MMR vaccine components was excluded by an in vivo approach, consisting in skin prick tests, intradermal tests, and subcutaneous injection test, corroborated by vaccine-specific B-lymphocyte proliferation assay, ex vivo. T-cell proliferation in response to MMR vaccine was also excluded. Eventually, the boy was inoculated with MMR vaccine and was readmitted to school.Conclusions The diagnostic strategy adopted appears feasible and easy-to-perform and may be adopted in controversial cases (as the one reported), characterized by previous severe allergic reactions to egg. The B-lymphocyte proliferation assay we developed may represent a useful and reliable tool not only in research but also in clinical practice.
Intestinal Parasites In Children of Cochabamba – Bolivia
Authors: Alvarez Ivana Camacho , Goyens Philippe , Jacobs Frédérique , López J. Marcela Luizaga 
Published: October 2020

Abstract
Background: A high percentage of the population in Latin America lives with intestinal parasitic infections, neglected tropical diseases frequently not treated. Intestinal parasitism is associated with nutritional diseases but the information about the epidemiological situation in countries like Bolivia is scarce. Environmental conditions play an important role in the prevalence of certain parasites. The main objective was to know the current situation of parasitic infections among children under twelve years old from different geographical areas of the department of Cochabamba – Bolivia. Methods: We analysed the laboratory reports of four second-line hospitals of different areas and the Tertiary Care Hospital. Results of stool examinations performed between 2011 and 2015 in children under twelve years of age were collected. Results: We gathered the results of 23221 examinations. The 89 % of children were less than five years old. Pathogenic parasites were found in 31 %. Entamoeba histolytica and Giardia lamblia were the two most prevalent parasites in all areas. Helminths were found in only 19% of positive samples and Ascaris lumbricoides was the most prevalent. Parasitic infections are more frequent in tropical area and helminths are highly concentrated in this area. Discussion and Conclusions: Parasitic infections in children are still very prevalent in Bolivia. Protozoan infections are the major problem while the prevalence of helminths seems to be decreasing. The most vulnerable population is still concentrated in tropical areas where the risk of parasitic infection is probably increased due to the environmental conditions. Our results will enable the planning of more efficient policies to control parasitic diseases.
Changes After Cancer Diagnosis and Return to Work: Moving Forward Without Direction
Authors: Bae Ka Ryeong , Cho Juhee 
Published: October 2020

Abstract
Background: The purpose of this study was to understand the unmet needs of cancer patients and identify the necessary factors to develop a vocational intervention program based on cancer patients’ work-related experience after cancer diagnosis.Methods: Semi-structured individual in-depth interviews were conducted with 50 cancer patients who were working at the time of diagnosis at a university hospital in Seoul, South Korea from July to September of 2017. Interview data were analyzed using qualitative content analysis.Results: ‘The changes patients experienced after cancer diagnosis’ were categorized into Personal and socio-environmental changes. ‘Personal changes’ were changes within the patient that were further divided into ‘physical’, ‘psychological’ and ‘spiritual’ changes while ‘socio-environmental changes’ were changes in either ‘attitude’ and ‘relationship’ of other people cancer patients encountered. In addition to these post-diagnosis changes, the following 4 major factors related to return-to-work were identified to affect patients’ experience: ‘fear of cancer recurrence’, ‘financial status’, ‘informational support’, and ‘working environment’.Conclusion: Cancer patients’ working status was determined by the interaction between the patients’ post-diagnosis changes and 4 factors related to return-to-work, with the factors’ positive or negative effect leading to return-to-work. In particular, cancer patients faced difficulties processing and appropriately responding to the potential changes occurring after cancer diagnosis due to lack of information. Based on these findings, we plan to develop an educational intervention reflecting these factors to promote cancer patients’ return-to-work. Educational materials and intervention programs informing patients on these changes and factors may facilitate their return-to-work after diagnosis.
Time Trends and Regional Disparities of Maternal Mortality Ratio: Evidences From China, 1990-2018.
Authors: Chen Lu , Feng Penghui , Shaver Lance , Wang Zengwu 
Published: October 2020

Abstract
Introduction China is one of the few countries to achieve Millennium Development Goal 4 and 5. This study aimed to access the levels and trends of maternal mortality ratio (MMR) in China from 1990 to 2018. Methods Using descriptive epidemiology, we collected the data from the China Health Statistics Yearbooks and the China Statistical Yearbooks to describe changes in MMRs, hospital delivery rate, per capita GDP, policies, health expenditure indictors and per capita annual income by region from 1990 to 2018. Spearman correlation analysis was used to assess the relevance between MMR and health expenditure indicators. Results The MMR decreased by 79.4% from 1990 to 2018 in China, and the MMR was remarkably lower in the eastern China than that in the western China. In the context of the widening gap between urban and rural wealth from 1990 to 2018, the urban-rural MMR gap narrowed. The MMR in China has always been higher in rural areas than in urban areas. After the implementation of the Two-Child policy in 2015, the urban MMR continued to decline in 2015-2018, and the rural MMR rebounded in 2017. The hospital delivery rate in China has been on the rise, with almost all pregnant women giving birth in hospital by 2018. The MMR was negatively correlated with the percentage of government health expenditure in the total health expenditure. Obstetric hemorrhage has always been the leading cause of maternal death from 1990 to 2018 in urban and rural areas. Conclusions China has made remarkable progress in maternal survival, despite regional differences still exist. The implementation of the Two-Child policy slowed down the decline of MMR in rural areas. Chinese government should focus on the maternal health in western provinces, rural areas, and the floating population in urban areas.
Comparing Primary Care Interprofessional and Non-interprofessional Teams on Access to Care and Health Services Utilization in Ontario, Canada: A Retrospective Cohort Study
Authors: Haj-Ali Wissam , Hutchison Brian , Moineddin Rahim , Wodchis Walter , Glazier Rick 
Published: October 2020

Abstract
Background: Many countries, including Canada, have introduced primary care reforms to improve health system functioning and value. The purpose of this study was to examine the association between receiving care from interprofessional primary care teams and access to care and health services utilization. Methods: We conducted a retrospective cohort study linking population-based administrative databases to Ontario’s Health Care Experience Survey (HCES) between 2012 and 2018. We adjusted for physician group characteristics as well as individual physician and patient characteristics while assessing the relationship between receiving care from interprofessional teams and the outcomes of interest.Results: As of March 31st, 2015, there were 465 physician groups with HCES respondents of which 177 (38.0%) were interprofessional teams and 288 (62.0%) were non-interprofessional teams in the same blended capitation reimbursement model. In this period, there were 4,518 physicians with HCES respondents, of whom 2,131 (47.2%) were in interprofessional teams and 2,387 (52.8%) were in non-interprofessional teams. There were 10,102 HCES respondents included in this study, of whom 42.4% were in interprofessional teams and 42.3% were in non-interprofessional teams. After adjustment, we found that being in an interprofessional team was associated with an increase in the odds of patients reporting same/next day access to care by 12.0% (OR=1.12 CI=1.00 to 1.24 p-value 0.0436) and a decrease in the odds of patients reporting walk-in clinic use by 16% (OR=0.84 CI=0.75 to 0.94 p-value 0.0019). After adjustment, there were no significant differences in patient-reported after-hours access to care and emergency department use.Conclusions: Ontario has invested heavily in interprofessional primary care teams. As compared to patients in non-interprofessional teams, patients in interprofessional teams self-reported more timely access to care and less walk-in clinic use but no significant difference in self-reported access to after-hours care or in emergency department use. For jurisdictions aiming to expand physician voluntary participation in interprofessional teams, our study results inform expectations around access to care and health services utilization.
A New Personalised Telehealth Model in Chronic Pediatric Diseases and Disability During The&nbsp;COVID-19 ERA
Authors: Mercuri Eugenio , Zampino Giuseppe , Morsella Alisha , Pane Marika , Onesimo Roberta , Angioletti Carmen , Valentini Piero , Rendeli Claudia , Ruggiero Antonio , Nanni Lorenzo , Chiaretti Antonio , Vento Giovanni , Korn David , Meneschincheri Emilio , Sergi Paolo , Scambia Giovanni , Ricciardi Walter , Cambieri Andrea , De Belvis Antonio Giulio 
Published: October 2020

Abstract
Background: Suspending ordinary care activities during the COVID-19 pandemic made it necessary to find alternative routes to comply with care recommendations not only for acute health needs but also for patients requiring follow-up and multidisciplinary visits. We present the ‘Contactless’ model, a comprehensive operational tool including a plurality of services delivered remotely, structured according to a complexity gradient, aimed to cover diagnostic procedures and monitor disease progression in chronic pediatric patients. Methods: A multidisciplinary and multiprofessional project team was recruited, in collaboration with patients’ associations, to map a panel of available Evidence-Based solutions and address individual needs in full respect of the concept of personalized medicine. The solutions include a number of services from videoconsultations to more structure videotraining sessions.Results: A modular framework made up of four three Macro-levels of complexity - Contactless Basic, Intermediate and Advanced - was displayed as an incremental set of services and operational planning establishing each phase, from factors influencing eligibility to the delivery of the most accurate and complex levels of care. Conclusion: The multimodal, multidisciplinary ‘Contactless’ model allowed the inclusion of all Units of our Pediatric Department and families with children with disability or complex chronic conditions. The strengths of this project rely on its replicability outside of pediatrics and in the limited resources needed to practically impact patients, caregivers and professionals involved in the process of care. Its implementation in the future may contribute to reduce the duration of hospital admissions, money and parental absence from work.
A Simple Method for Diagnosing Gallbladder Malignant Tumors with Subserosa Invasion by Endoscopic Ultrasonography
Authors: Sugimoto Mitsuru , Irie Hiroki , Takasumi Mika , Hashimoto Minami , Oka Yuka , Takagi Tadayuki , Konno Naoki , Suzuki Rei , Asama Hiroyuki , Sato Yuki , Nakamura Jun , Kato Tsunetaka , Kobashi Ryoichiro , Hashimoto Yuko , Marubashi Sigeru , Hikichi Takuto , Ohira Hiromasa 
Published: October 2020

Abstract
Background: If the depth of gallbladder malignant tumor (GBMT) invasion is deeper than the subserosa (ss), cholecystectomy is insufficient. In past reports that used endoscopic ultrasonography (EUS) to diagnose the depth of tumor invasion, it was difficult to diagnose GMBT invasion in the ss without a narrow or disrupted lateral hyperechoic layer (LHEL). Therefore, we developed a simple preoperative method to diagnose GBMTs with ss invasion. Methods: Forty-nine GBMT patients who underwent both EUS and surgery were enrolled: 15 patients whose tumors invaded the mucosa (m) or muscularis propria (mp) were classified as the “shallow group”, and 34 patients whose tumors invaded the ss were classified as the “deep group”. The EUS findings were compared between the two groups.Results: An irregular (narrow or thickened) LHEL was significantly more frequently observed on EUS in the deep group than in the shallow group. The diagnosis of ss invasion based on an irregular LHEL had the highest sensitivity and accuracy among the EUS imaging parameters (sensitivity 97.1% (33/34), specificity 86.7% (13/15), accuracy 93.8% (46/49)). When the deep group was limited to patients with a tumor depth of ss, the results were similar. When an irregular LHEL was used, the diagnosability of GBMTs with ss invasion was not significantly different between EUS specialists and beginners.Conclusions: An irregular (thickened or narrow) LHEL observed on EUS could be a reliable and simple method of diagnosing GBMTs with ss invasion and could contribute to choosing an appropriate surgical method.Trial Registration: not applicable
Enhancing Sleep Quality for Nursing Home Residents with Dementia: A Pragmatic Randomized Controlled Trial of an Evidence-Based Frontline Huddling Program
Authors: Snow A. Lynn Lynn , Loup Julia , Morgan Robert O. , Richards Kathy , Parmelee Patricia , Baier Rosa , McCreedy Ellen , Frank Barbara , Brady Cathie , Fry Liam , McCullough Megan , Hartmann Christine W. 
Published: October 2020

Abstract
Background

Disturbed sleep places older adults at higher risk for frailty, morbidity, and even mortality. Yet, nursing home routines frequently disturb residents’ sleep through use of noise, light, or efforts to reduce incontinence. Nursing home residents with Alzheimer’s disease and or related dementias—almost two-thirds of long-stay nursing home residents—are likely to be particularly affected by sleep disturbance. Addressing these issues, this study protocol implements an evidence-based intervention to improve sleep: a nursing home frontline staff huddling program known as LOCK. The LOCK program is derived from evidence supporting strengths-based learning, systematic observation, relationship-based teamwork, and efficiency.
Methods

This study protocol outlines a NIH Stage III, real-world hybrid efficacy-effectiveness pragmatic trial of the LOCK sleep intervention. Over two phases, in a total of 27 non-VA nursing homes from 3 corporations, the study will (1) refine the LOCK program to focus on sleep for residents with dementia, (2) test the impact of the LOCK sleep intervention for nursing home residents with dementia, and (3) evaluate the intervention’s sustainability. Phase 1 (1 year; n = 3 nursing homes; 1 per corporation) will refine the intervention and train-the-trainer protocol and pilot-tests all study methods. Phase 2 (4 years; n = 24 nursing homes; 8 per corporation) will use the refined intervention to conduct a wedge-design randomized, controlled, clinical trial. Phase 2 results will measure the LOCK sleep intervention’s impact on sleep (primary outcome) and on psychotropic medication use, pain and analgesic medication use, and activities of daily living decline (secondary outcomes). Findings will point to inter-facility variation in the program’s implementation and sustainability.
Discussion

This is the first study to our knowledge that applies a dementia sleep intervention to systematically address known barriers to nursing home quality improvement efforts. This innovative study has future potential to address clinical issues beyond sleep (safety, infection control) and expand to other settings (assisted living, inpatient mental health). The study’s strong team, careful consideration of design challenges, and resulting rigorous, pragmatic approach will ensure success of this promising intervention for nursing home residents with dementia.
Trial registration:
NCT04533815, ClinicalTrials.gov, August 20, 2020.
Association between Psychiatric Disorders and Glomerular Disease.
Authors: Desmond Hailey E. , Lindner Clare , Troost Jonathan P. , Held Zack , Modes Meg , Callaway Andrea , Oh Gia J. , Lafayette Richard , O’Shaughnessy Michelle , Elliot Matthew , Adler Sharon , Kamil Elaine S. , Pesenson Anne , Selewski David T. , Gipson Patrick E. , Carlozzi Noelle E. , LaVigne Joseph , Gipson Debbie S. , Massengill Susan F. 
Published: October 2020

Abstract
Background: Patients with chronic health conditions are at heightened risk for psychiatric disorders; yet, little is known about the occurrence of psychiatric disorders or associations with patient and disease characteristics in glomerular disease.Methods: This study included patients with glomerular disease enrolled in the Kidney Research Network multisite patient registry. Registry data includes encounter, diagnoses, medication, lab, and vital signs data extracted from participants’ electronic health records. ICD9/10 diagnosis codes were used to identify subset of psychiatric disorders focused on anxiety, mood, and behaviorial disorders. Time-varying Cox proportional hazards models were used to analyze time from onset of kidney disease to diagnosis of psychiatric disorder. Models adjusted for age, sex, race, ethnicity, and time-varying treatment, estimated glomerular filtration rate (eGFR), and proteinuria. Analogous models examined diagnosis of psychiatric disorder as a predictor of time to end stage kidney disease (ESKD).Results: Data were available for 943 participants with a median of 58 months of follow-up. 109 (12%) participants were ever diagnosed with a psychiatric disorder during follow up. Estimated risk of psychiatric diagnosis after kidney disease was 14.7 cases per 1,000 person-years, and was highest among adolescents. Adjusted analyses found adolescent age (vs. Adult, HR=2.03, CI=1.23-3.35), Asian race (vs. White, HR=0.34, 95% CI=0.16-0.70) and steroid therapy (HR=2.27, 95% CI=1.53-3.38) were associated with psychiatric diagnosis. Psychiatric diagnosis was also associated with progression to ESKD (HR=2.47, 95% CI=1.55-3.95) after adjusting for kidney diagnosis, eGFR at onset, proteinuria over time, and steroid therapy.Discussion: Psychiatric disorders were documented in approximately one eighth of patients with glomerular disease and correlated with clinical disease characteristics. Conclusions: These findings suggest mental health screening may be warranted in patients with glomerular disease.
Evaluation of Underlying Causative Factors for Earthquake-Induced Landslides and Landslide Susceptibility Mapping in Upper Indrawati Watershed, Nepal
Authors: Gautam Pawan , Kubota Tetsuya , Aditian Aril 
Published: October 2020

Abstract
The main objectives of this study are to assess the underlying causative factors for landslide occurrence due to earthquake in upper Indrawati Watershed of Nepal and evaluating the region prone to landslide using Landslide Susceptibility Mapping (LSM). We used logistic regression (LR) for LSM on geographic information system (GIS) platform. Nine causal factors (CF) including slope angle, aspect, elevation, curvature, distance to fault and river, geological formation, seismic intensity, and land cover were considered for LSM. We assessed the distribution of landslide among the classes of each CF to understand the relationship of CF and landslides. The northern part of the study area, which is dominated by steep rocky slope have a higher distribution of earthquake-induced landslides. Among the CF, 'slope' showed the positive correlation as landslide distribution is increasing with increasing slope. However, LR analysis depict 'distance to the fault' is the best predictor with the highest coefficient value. Susceptibility map was validated by assessing the correctly classified landslides under susceptibility categories, generated in five discrete classes using natural break (Jenk) methods. Calculation of area under curve (AUC) and seed cell area index (SCAI) were performed to validate the susceptibility map. The LSM approach shows good accuracy with respective AUC value for success rate and prediction rate of 0.795 and 0.702. Similarly, the decreasing SCAI value from very low to very high susceptibility categories advise satisfactory accuracy of LSM approach.