bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effectiveness of quarantine of Wuhan city against the Corona Virus Disease 2019 (COVID‐19): A well‐mixed SEIR model analysis
Authors: Hou Can , Chen Jiaxin , Zhou Yaqing , Hua Lei , Yuan Jinxia , He Shu , Guo Yi , Zhang Sheng , Jia Qiaowei , Zhao Chenhui , Zhang Jing , Xu Guangxu , Jia Enzhi 
Published: April 2020

AbstractA novel coronavirus pneumonia, first identified in Wuhan City and referred to as COVID‐19 by the World Health Organization, has been quickly spreading to other cities and countries. To control the epidemic, the Chinese government mandated a quarantine of the Wuhan city on January 23, 2020. To explore the effectiveness of the quarantine of the Wuhan city against this epidemic, transmission dynamics of COVID‐19 have been estimated. A well‐mixed “susceptible exposed infectious recovered” (SEIR) compartmental model was employed to describe the dynamics of the COVID‐19 epidemic based on epidemiological characteristics of individuals, clinical progression of COVID‐19, and quarantine intervention measures of the authority. Considering infected individuals as contagious during the latency period, the well‐mixed SEIR model fitting results based on the assumed contact rate of latent individuals are within 6–18, which represented the possible impact of quarantine and isolation interventions on disease infections, whereas other parameter were suppose as unchanged under the current intervention. The present study shows that, by reducing the contact rate of latent individuals, interventions such as quarantine and isolation can effectively reduce the potential peak number of COVID‐19 infections and delay the time of peak infection.
Dysregulation of synaptic pruning as a possible link between intestinal microbiota dysbiosis and neuropsychiatric disorders
Authors: Eltokhi Ahmed , Janmaat Isabel E. , Genedi Mohamed , Haarman Bartholomeus C. M. , Sommer Iris E. C. 
Published: April 2020

AbstractThe prenatal and early postnatal stages represent a critical time window for human brain development. Interestingly, this window partly overlaps with the maturation of the intestinal flora (microbiota) that play a critical role in the bidirectional communication between the central and the enteric nervous systems (microbiota‐gut‐brain axis). The microbial composition has important influences on general health and the development of several organ systems, such as the gastrointestinal tract, the immune system, and also the brain. Clinical studies have shown that microbiota alterations are associated with a wide range of neuropsychiatric disorders including autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia, and bipolar disorder. In this review, we dissect the link between these neuropsychiatric disorders and the intestinal microbiota by focusing on their effect on synaptic pruning, a vital process in the maturation and establishing efficient functioning of the brain. We discuss in detail how synaptic pruning is dysregulated differently in the aforementioned neuropsychiatric disorders and how it can be influenced by dysbiosis and/or changes in the intestinal microbiota composition. We also review that the improvement in the intestinal microbiota composition by a change in diet, probiotics, prebiotics, or fecal microbiota transplantation may play a role in improving neuropsychiatric functioning, which can be at least partly explained via the optimization of synaptic pruning and neuronal connections. Altogether, the demonstration of the microbiota's influence on brain function via microglial‐induced synaptic pruning addresses the possibility that the manipulation of microbiota‐immune crosstalk represents a promising strategy for treating neuropsychiatric disorders.
Monthly precipitations over semi‐arid basins in Northern Africa: Homogenization and trends
Authors: Abahous Houria , Guijarro Jose A. , Sifeddine Abdelfettah , Chehbouni Abdelghani , Ouazar Driss , Bouchaou Lhoussaine 
Published: April 2020

AbstractLong‐term and high quality observed climate data are required to analyse with reduced uncertainty temporal and spatial climate variability. The aim of this work is the quality control, the reconstruction and homogenization of monthly precipitation observed in semi‐arid basins within Souss‐Massa region in North Africa during the period 1933–2010. Data recorded in local meteorological stations underwent a neighbour‐based homogenization algorithm. We apply Mann‐Kendall test and Sen's method to raw and homogenized time series to calculate trends and their magnitude. The greatest variation in data properties is highlighted for the trend analysis where the homogenization process allows the detection of a higher number of the statistically significant negative trend with 95 and 99% confidence levels.
Does Cognitive Style Moderate Expected Evaluation and Adolescents' Creative Performance: An Empirical Study
Authors: Lei Weina , Deng Wenbo , Zhu Rongjuan , Runco Mark A. , Dai David Yun , Hu Weiping 
Published: April 2020

ABSTRACTTwo studies investigated the effects of cognitive and school environmental factors on adolescents' creative performance. The first study tested the effects of expected evaluation and cognitive style on creativity among 89 high school students. The second study tested the effects of evaluation type and cognitive style on creativity among 92 high school students. Study 1 found main effects of expected evaluation and cognitive style on creativity. The interaction between expected evaluation and cognitive style was statistically significant. Under an experimental condition of expected evaluation, field‐dependent adolescents performed more creatively (i.e., higher originality) than those without expected evaluation. Study 2 uncovered main effects of expected evaluation type and cognitive style on creativity but no interactions between expected evaluation type and cognitive style. Adolescents performed better on the dimension of flexibility in a controlling evaluation condition, compared with adolescents in informational evaluation condition, and field‐independent adolescents showed more fluency and originality than field‐dependent adolescents. Together, this research provides a better understanding of the effects of expected evaluation and cognitive style on adolescents' creative performance. Implications for further research are discussed.
Yield and nutritional quality of highbush blueberry genotypes trialled in a Mediterranean hot summer climate
Authors: Mazzoni Luca , Balducci Francesca , Di Vittori Lucia , Scalzo Jessica , Capocasa Franco , Zhong Chuan‐Fei , Forbes‐Hernandez Tamara Y , Giampieri Francesca , Battino Maurizio , Mezzetti Bruno 
Published: April 2020

AbstractBACKGROUNDCultivation of highbush blueberry (Vaccinium corymbosum L.) has been increasing in Europe in recent years, in particular due to the availability of new genotypes suitable for cultivation in many different environmental conditions. The aim of this study was to evaluate the resilience and nutritional quality of 11 highbush blueberry cultivars and two new selections (from the New Zealand Institute for Plant and Food Research Ltd breeding program) in Mediterranean hot summer climate conditions by measuring plant yield, seasonality, fruit sensorial traits, and phytochemical content in the fruits.RESULTSThe new blueberry genotype PFR005 showed a high level of adaptability to these environmental conditions, with the highest total plant yield, whereas PFR075 was the best genotype for nutritional characteristics. Among the cultivars, ‘Cosmopolitan’ showed the maximum average fruit weight, ‘Blueray’ and ‘Hortblue Poppins’ demonstrated a good sensorial profile, while the best cultivars from the nutritional point of view were ‘Hortblue Poppins’, ‘Hortblue Petite’, and ‘Early Blue’.ConclusionNew cultivars and new genotypes able to satisfy the needs of different users, have been identified. The integration of germplasm evaluation with a tailored breeding program will help to create new cultivars that will be useful for the expansion of blueberry cultivation in hot Mediterranean summer climate conditions, which up to now have limited this crop. © 2020 Society of Chemical Industry
Multiple drivers of production and particle export in the western tropical North Atlantic
Authors: Korte Laura F. , Brummer Geert‐Jan A. , van der Does Michèlle , Guerreiro Catarina V. , Mienis Furu , Munday Chris I. , Ponsoni Leandro , Schouten Stefan , Stuut Jan‐Berend W. 
Published: April 2020

AbstractTo assess the impacts of Amazon River discharge, Saharan dust deposition, N2‐fixation and mixed‐layer deepening on the biological carbon pump, sediment traps were moored from October 2012 to November 2013 at two sites in the western tropical North Atlantic (49°W,12°N/57°W,12°N). Particle exports interpreted along with satellite‐ and Argo‐float data show peak fluxes in biogenic silica (31 mg m−2 d−1) and organic carbon (25 mg m−2 d−1) during the fall of 2013 that were ten to five times higher than any time earlier during the year. These high export fluxes occurred in tandem with high surface chlorophyll a concentrations associated with the dispersal of the Amazon River plume, following retroflection into the North‐Atlantic‐Counter‐Current. High fucoxanthin fluxes (> 80 μg m−2 d−1) and low δ15N‐values (−0.6‰) suggest a large contribution by marine diatom‐diazotrophic‐associations, possibly enhanced by wet Saharan dust deposition. During summer, the Amazon River plume resulted in high mass fluxes at 57°W that were enriched in biogenic silica but weakly influenced by diazotrophic‐associations compared to the fall event at 49°W. High carbonate‐carbon fluxes (17 mg m−2 d−1) dominated a second single event at 49°W during spring that was likely triggered by mixed‐layer deepening. Rain‐ratios of BSi/Ccarb amounted to 1.7 when associated with high export fluxes linked to the Amazon River plume. Compared to an annual average of 0.3, this indicates a more efficient uptake of CO2 via the biological pump compared to when the plume was absent, hence supporting earlier observations that the Amazon River plume is important for ocean CO2 sequestration.
Injectable Enzyme‐Based Hydrogel Matrix with Precisely Oxidative Stress Defense for Promoting Dermal Repair of Burn Wound
Authors: Zhang Dongmei , Wang Bulei , Sun Yajuan , Wang Changhao , Mukherjee Somnath , Yang Cheng , Chen Yashao 
Published: April 2020

AbstractBurn wound healing remains a challenging health problem worldwide due to the lack of efficient and precise therapy. Inherent oxidative stress following burn injury is importantly responsible for prolonged inflammation, fibrotic scar, and multiple organ failure. Herein, a bioinspired antioxidative defense system coupling with in situ forming hydrogel, namely, multiresponsive injectable catechol‐Fe3+ coordination hydrogel (MICH) matrix, is engineered to promote burn‐wound dermal repair by inhibiting tissue oxidative stress. This MICH matrix serves as the special traits of “Fe‐superoxide dismutases,” small molecular antioxidant (vitamin E), and extracellular matrix (ECM) in alleviating cellular oxidative damage, which demonstrates precise scavenging on reactive oxygen species (ROS) of different cellular locations, blocking lipid peroxidation and cell apoptosis. In in vivo burn‐wound treatment, this MICH promptly integrates with injured surrounding tissue to provide hydration microenvironment and physicochemical ECM for burn wounds. Importantly, the MICH matrix suppresses tissue ROS production, reducing the inflammatory response, prompting re‐epithelization and neoangiogenesis during wound healing. Meanwhile, the remodeling skin treated with MICH matrix demonstrates low collagen deposition and normal dermal collagen architecture. Overall, the MICH prevents burn wound progression and enhances skin regeneration, which might be a promising biomaterial for burn‐wound care and other disease therapy induced by oxidative stress.
Ultrasound can differentiate inclusion body myositis from disease mimics
Authors: Leeuwenberg Kristofoor E. , van Alfen Nens , Christopher‐Stine Lisa , Paik Julie J. , Tiniakou Eleni , Mecoli Christopher , Doorduin Jonne , Saris Christiaan G.J. , Albayda Jemima 
Published: April 2020

AbstractIntroductionThe diagnosis of inclusion body myositis (IBM) can be challenging, and its presentation can be confused with other forms of myositis or neuromuscular disorders. In this study we evaluate the ability of quantitative muscle ultrasound to differentiate between IBM and mimicking diseases.MethodsPatients 50 years of age and older were included from two specialty centers. Muscle echogenicity and muscle thickness of four characteristically involved muscles in IBM were measured and compared with polymyositis (PM)/dermatomyositis (DM), other neuromuscular disorders, and healthy controls.ResultsEchogenicity was higher and muscle thickness generally lower in all four muscles in IBM compared with PM/DM and normal controls. When comparing IBM with the comparator groups, the flexor digitorum profundus was the most discriminative muscle.DiscussionUltrasound appears to be a good test to differentiate established IBM from PM/DM and neuromuscular controls, with value as a diagnostic tool for IBM.
Hydrologic Correlates of Reproductive Success in the Alligator Gar
Authors: Smith Nathan G. , Buckmeier David L. , Daugherty Daniel J. , Bennett Daniel L. , Sakaris Peter C. , Robertson Clinton R. 
Published: April 2020

Abstract
Previous work relating adult age data to historic hydrology indicated that strong year-classes of Alligator Gar Atractosteus spatula were rare, tied to major flooding events, and linked to the inundation and connectivity of floodplain habitats. Although spawning habitat suitability criteria have been correlated with successful recruitment in Texas Alligator Gar populations, direct evaluation of recruitment documenting young-of-the-year (age-0) presence or abundance has not been reported. To specify conditions associated with successful spawning and recruitment of Alligator Gar, we sampled for age-0 fish monthly from May to July 2013–2017 in the Trinity River and from May to July 2015–2017 in Choke Canyon Reservoir. Suitability criteria predicted strong year-classes in 2015 and 2016 for the Trinity River and in 2015 for Choke Canyon Reservoir; the predictions were confirmed by the presence of abundant age-0 Alligator Gar in those systems and years. Hatch dates of juvenile Alligator Gar were estimated from otoliths and compared to corresponding environmental and hydrologic conditions. Hatch date analyses indicated a protracted spawning duration in 2015 associated with extended widespread flooding and a narrower range of spawning dates in 2016. Due to rapid growth and variable gear efficacy relative to fish size, multiple gears were required to assess the full size range of age-0 Alligator Gar. A standardized sampling framework that included visual searching and floating mini-fyke nets effectively sampled age-0 Alligator Gar from 15 to 650 mm TL. We recommend a two-tiered approach for predicting and monitoring Alligator Gar recruitment. First, the monitoring of hydrology and the application of suitability criteria can provide an early predictor of potential Alligator Gar reproductive success. If conditions are favorable for spawning, then sampling for age-0 Alligator Gar can confirm recruitment and can give an indication of the spatial extent (visual searching) and relative abundance (visual searching and/or mini-fyke nets) of successful reproduction.
Two‐year safety and efficacy outcomes for the treatment of overactive bladder using a long‐lived rechargeable sacral neuromodulation system
Authors: Blok Bertil , Van Kerrebroeck Philip , de Wachter Stephan , Ruffion Alain , Van der Aa Frank , Perrouin‐Verbe Marie Aimée , Elneil Sohier 
Published: April 2020

AbstractAimsSacral neuromodulation (SNM) therapy for overactive bladder (OAB) has proven long‐term safety and efficacy. Historically, the only commercially available SNM device was nonrechargeable requiring replacement surgery due to battery depletion. The Axonics System is the first rechargeable SNM device and is qualified to last a minimum of 15 years in the body. The study objective was to evaluate the safety and efficacy of this rechargeable SNM system. This study reports 2‐year outcomes.MethodsA total of 51 subjects were implanted with the Axonics System in a single nonstaged procedure. Subjects had OAB, confirmed on a 3‐day voiding diary (≥8 voids/day and/or ≥2 incontinence episodes over 72 hours). Test Responders were defined as subjects that were responders at 1 month postimplant. The efficacy analysis included therapy responder rates, change in the quality of life, and subject satisfaction reported in Test Responders (n = 30) and all implanted subjects (n = 37) that completed the follow‐up visits. Adverse events (AEs) are reported in all implanted subjects.ResultsAt 2 years, 90% of the Test Responders continued to respond to the therapy based on voiding diary criteria. Satisfaction with therapy was reported by 93% of subjects and 86% found their charging experience acceptable. Of the urinary incontinence Test Responders, 88% continued to be responders at 2 years, and 28% were completely dry. There were no unanticipated (AEs) or serious device‐related AEs.ConclusionsThe Axonics System® provides sustained clinically meaningful improvements in OAB subjects at 2 years. There were no serious device‐related AEs. Subjects reported continued satisfaction with their therapy.
Game therapy a new approach to treat women facing mixed urinary incontinence: A study protocol
Authors: Oliveira Maria Clara Eugênia , Bezerra Livia Oliveira , Melo Ângelo Priscylla Hellouyse , de Oliveira Maiara Costa , Silva‐Filho Edson , Ribeiro Tatiana Souza , Pegado Rodrigo , Micussi Maria Thereza Albuquerque Barbosa Cabral 
Published: April 2020

AbstractAimsTo describe a pelvic floor muscle training (PFMT) isolated and associated with game therapy (PFMT + GT) for women facing mixed urinary incontinence (MUI) during climacteric period.MethodsTo standardize a randomized controlled clinical trial intervention, a protocol was created, in an attempt to decrease women's symptomatology generated by MUI, through pelvic floor and abdomino‐loin‐pelvic muscles strength, and endurance. This study protocol will be composed of 32 volunteers, divided into two groups of 16. They will perform PFMT isolated or PFMT + GT, twice a week during 8 weeks. Interventions will last 40 minutes and will be divided into warming (5 minutes), training (30 minutes), and 5 minutes will be composed of resting time between exercises (1 minute each). Isolated PFMT sessions will be performed through four modalities of exercises: diaphragmatic, bridge, abdominal (plank), and pelvic mobility. PFMT + GT training will be carried out by using Wii Fit Plus games, such as Lotus Focus, Penguin Slide, Basic Step, and Hula Hoop from Wii equipment. Assessments will occur before, after, and 1 month after interventions. Vaginal manometry, 1‐hour Pad Test, International Consultation on Incontinence Questionnaire—Short Form (ICIQ‐SF), and Patient Global Intervention (PGI) will be used to evaluate the sample.ConclusionsIt is expected greater increase on pelvic floor muscle (PFM) strength, endurance, vaginal pressure for PFMT + GG. Moreover, it is supposed that PFMT + GT volunteers present better treatment adherence due to games motivational inclusion.
Steam explosion of windmill palm fiber as the filler to improve the acoustic property of rigid polyurethane foams
Authors: Ju Zehui , He Qian , Zhang Haiyang , Zhan Tianyi , Chen Liangsong , Li Suxia , Hong Lu , Lu Xiaoning 
Published: April 2020

AbstractRigid polyurethane foam is a common sound absorption material in the construction owing to its structure that can effectively absorb sound waves by air friction and structural vibration. Windmill palm fibers pretreated with acid, alkali, or steam explosion were employed with polyurethane foam to improve foam acoustic performance in this study. The open porosity of the composite foam is closely related to the different treatments of windmill palm fiber and the content of windmill palm fiber in the composite. Steam explosion treatment removes silicon and wax layers on the surface of the windmill palm fiber, and the increased surface area after steam explosion provides a number of possible coupling reaction sites between the fiber and matrix. The model calculation shows that high airflow resistivity leads to high acoustic property, which is approach with the experimental results. The peak value of acoustic property indicated that the optimal content of windmill palm fiber in the rigid polyurethane foams is 1 wt%.
Description of misdiagnosis and missed diagnosis of fetal complex heart malformations by prenatal echocardiography combined with postnatal cardiovascular casting
Authors: Wang Yu , Zhang Jiaqi , Feng Wei , Cao Haiyan , He Qiaoyue , Xu Jinzhi , Zeng He , Xie Mingxing 
Published: April 2020

AbstractObjectiveTo compare prenatal echocardiography with postnatal cardiovascular casting for detection of fetal cardiovascular malformations, and to discuss the causes of prenatal misdiagnosis and missed diagnosis.MethodsWe retrospectively identified patients from 2013 to 2018 at our Maternal‐Fetal Medicine Center who were reported to have a fetal diagnosis of severe congenital heart malformations (CHMs). Subjects had postnatal confirmation of CHMs. Prenatal and postnatal medical records, including ultrasound results and casting findings, were reviewed and analyzed.ResultsPostnatal casting showed that all 35 fetuses had complex CHMs. In these 35 cases, 90 cardiovascular malformations were found by postnatal casting, and 69 were detected by prenatal echocardiography. Among the other 21 cardiovascular malformations, 7 were misdiagnosed and 14 diagnoses were missed by prenatal ultrasound.ConclusionPrenatal echocardiography may lead to misdiagnosis and missed diagnoses, especially in cases with great arterial branching anomalies. Postnatal casting can demonstrate the configuration of the great vessels and smaller branches directly. Thus, understanding of such malformations via postnatal casting may help to improve prenatal diagnostic accuracy.
The isolation period should be longer: Lesson from a child infected with SARS‐CoV‐2 in Chongqing, China
Authors: Lin Jilei , Duan Jun , Tan Tingdan , Fu Zhou , Dai Jihong 
Published: April 2020

AbstractIn December 2019, COVID‐19 caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) outbroke in Wuhan, the capital city of Hubei province, China. The disease rapidly spread to other areas in China due to a huge population movement during the New Year Festival. Here, a 7‐year‐old child with SARS‐CoV‐2 infection in Chongqing, outside of Wuhan, Hubei province, was reported. This case suggested that children infected with SARS‐CoV‐2 are more likely to present milder manifestations than adults. The continuous positive real‐time reverse transcription‐polymerase chain reaction assay for SARS‐CoV‐2 in the child's throat swab sample indicated the isolation period for suspected child cases should be longer than 14 days.