bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-lived Dust Rings around HD 169142
Authors: Toci Claudia , Lodato Giuseppe , Fedele Davide , Testi Leonardo , Pinte Christophe 
Published: December 2019

Abstract
Recent Atacama Large Millimeter/submillimeter Array (ALMA) observations of the protoplanetary disk around HD 169142 reveal a peculiar structure made of concentric dusty rings: a main ring at ∼20 au, a triple system of rings at ∼55–75 au in millimetric continuum emission, and a perturbed gas surface density from the 12CO,13CO, and C18O (J = 2–1) surface brightness profile. In this Letter, we perform 3D numerical simulations and radiative transfer modeling exploring the possibility that two giant planets interacting with the disk and orbiting in resonant locking can be responsible for the origin of the observed dust inner rings structure. We find that in this configuration the dust structure is actually long lived while the gas mass of the disk is accreted onto the star and the giant planets, emptying the inner region. In addition, we also find that the innermost planet is located at the inner edge of the dust ring, and can accrete mass from the disk, generating a signature in the dust ring shape that can be observed in mm ALMA observations.
La créativité sous le prisme de l’innovation. Une enquête par entretiens semi-directifs auprès de 40 chercheurs industriels
Authors: Toustou Béatrice 
Published: December 2019

Alors que la littérature sur les facteurs favorisant la créativité et l’innovation a crû de façon conséquente en volume et en sophistication, un nombre de plus en plus important de chercheurs s’interroge sur l’emploi élusif et ambigu des notions de créativité et d’innovation, dans la littérature comme dans les organisations, au niveau du résultat comme sur l’aspect processuel. Une hypothèse implicite semble avoir été posée que les mêmes facteurs opèrent de manière similaire sur tous les types de créativité et d’innovation, indépendamment des contextes et des métiers. Du point de vue de la recherche, malgré leur proximité et leurs interférences, il apparaît que les deux champs sont indépendants, chacun caractérisé par des perspectives dominantes et une littérature spécifique.	L’objectif de cet article est de mieux comprendre la nature de la créativité au regard de l’innovation. Sur la base d’une étude qualitative menée par entretiens semi-directifs dans une unité de recherche et développement (R&D), nous explorons les représentations de 40 chercheurs industriels qui expérimentent la créativité dans un contexte d’innovation.
L’organisation digitale : des Ø et des 1 pour des opportunités et des risques
Authors: Barlatier Pierre-Jean , Burger-Helmchen Thierry 
Published: December 2019

L’avènement d’Internet a profondément changé l’environnement externe et l’architecture des organisations. Si chaque nouvelle vague de progrès technique se confronte à l’euphorie tout comme aux réactions dubitatives des utilisateurs réels et potentiels, aujourd’hui, les évolutions des technologies numériques ou « digitales » (applications mobiles, cloud computing , médias et réseaux sociaux, objets connectés, intelligence artificielle, impression 3D…) continuent de transformer les usages et modes de fonctionnement des organisations. Ces technologies numériques, rapidement diffusées et adoptées, bouleversent les manières des organisations de produire des biens et services, d’interagir avec leur environnement ou encore d’exploiter les opportunités à la recherche d’avantages concurrentiels. Les changements induits par cette évolution structurelle sont profonds, les organisations voient leurs capacités d’intégration et leur agilité testées par le numérique pour in fine, dans leur majorité, accuser un retard par rapport aux avantages attendus initialement, les laissant dans le flou concernant leur « avenir digital ». En outre, les changements réels subis ou introduits par les organisations suite au développement du numérique impactent leurs pratiques mais aussi les théories de l’entreprise. La théorie des organisations est prise en défaut par rapport aux nouvelles architectures organisationnelles qui apparaissent et dont l’analyse pose de nombreuses questions aux chercheurs. Ainsi, les contributions de ce Numéro Spécial sur « l’organisation digitale » apportent de nouvelles perspectives sur l’étude des impacts de la digitalisation des organisations et leurs logiques et modes de fonctionnement.
FabLab : quel intérêt pour l’entrepreneur ?
Authors: Fonrouge Cécile 
Published: December 2019

Les FabLabs sont des nouveaux lieux dans lesquels on peut expérimenter et fabriquer au moyen d’outils numériques. Si les recherches précédentes ont documenté le phénomène, aucune ne s’est posée la question directe de l’intérêt pour l’entrepreneur. Quels intérêts ont les entrepreneurs à fréquenter ces nouveaux lieux ? Pour répondre à cette question, nous définissons les FabLabs dans une lecture entrepreneuriale. Puis, une observation-participante d’un lancement de FabLab est menée sur deux ans. Trois questions de recherche sont isolées. Elles sont définies par contraste avec les concepts proches de tiers-lieu, communauté et écosystème. Les premiers résultats mettent en lumière le fait que ces lieux présentent des dimensions transgressives, de socialisation dans l’action et d’appropriation du numérique bien utiles pour l’entrepreneur.
Pouvoir et évaluation sur les plateformes de l’économie collaborative : Big Brother et le concours de beauté
Authors: Barbe Anne Sophie , Hussler Caroline 
Published: December 2019

Cet article se penche sur les dispositifs d’évaluation décentralisée mis en place sur les plateformes de l’économie collaborative. Prenant le contrepied d’une littérature qui les présente avant tout sous une perspective fonctionnaliste et habilitante, nous proposons de les étudier comme des dispositifs de pouvoir, au sens de Foucault. L’objectif de cet article est alors d’appréhender la manière dont ces dispositifs influencent les comportements des utilisateurs de ces plateformes. Pour ce faire, nous menons une étude de cas unique sur la plateforme de covoiturage BlaBlaCar. Nous adoptons une démarche qualitative s’appuyant sur des entretiens semi-directifs menés auprès des utilisateurs de la plateforme. Nous mettons en lumière que les utilisateurs intègrent le dispositif d’évaluation décentralisée dans leurs comportements de façon différenciée selon leurs niveaux d’expérience sur la plateforme. Nous avançons ensuite qu’au-delà de la peur de la sanction, c’est parce que l’utilisateur se représente lui-même et le monde par le prisme du dispositif d’évaluation que la modification des comportements opère. Le dispositif d’évaluation décentralisée assujettissant différemment des utilisateurs pourtant « pairs », nous mettons enfin en lumière qu’il crée des situations asymétriques entre utilisateurs, à la faveur des plus expérimentés.
Le Mai 68 de l’Éducation Physique : du trotskisme à la critique du sport et à l’Éducation corporelle
Authors: Gleyse Jacques 
Published: December 2019

En juillet-septembre 1968 paraît le brûlot : Sport, Culture et Répression , numéro 43 de la revue Partisans. Les auteurs de ce texte sont : François Maspero, Herbert Marcuse (traduction d’un texte de), André Rauch ( alias André Redna) Jean-Marie Brohm, François Gantheret, Ginette Bertrand, Michel Bernard 1 , Martial Barèges, Michel Bhussy, Pierre Vidal-Naquet, Fanny Vallon, Marc Roy. Il initie ce que l’on appellera par la suite la critique radicale freudo-marxiste du sport. Cette première publication, réalisée par des membres de groupes trotskystes ayant participé au mouvement de 1968, donnera lieu à beaucoup d’autres publications et à beaucoup d’autres actions : le boycott de la Coupe du monde de foot en Argentine en 1978, celui des Jeux olympiques de Moscou en 1980 (aux retombées internationales), la publication du journal L’Épique (journal satyrique), de la revue Quel Corps ? , la naissance du SGEN-CFDT EPS et de son journal Le Corps enchaîné , la création, au sein de la Fédération de l’Éducation nationale, en EPS, de la tendance École émancipée publiant Le Chrono enrayé . Par ailleurs, cela donnera lieu dès les années 1970-1980 à la contestation de l’hégémonisme du SNEP-U.A. et du SNEEPS et à l’essor de deux tendances : la Tendance du Manifeste et l’École émancipée, refusant la vision du sport éducatif proposée par la tendance majoritaire Unité Action (proche du PCF). Dix ans après, ces événements donneront lieu à des affrontements idéologiques et politiques. L’article s’attache à décrire la source politique de ces critiques, de ces publications et manifestations et leurs retombées dans le champ de l’EPS.
Safety and Bioavailability of Complete and Half-Dose Intravitreal Ziv-Aflibercept in an Experimental Model: Contralateral Eye Study
Authors: Lashay Alireza , Delrish Elham , Ashrafi Elham , Movassat Morteza , Asadi-Amoli Fahimeh , Dinarvand Rassoul , Abrishami Mojtaba 
Published: December 2019

BACKGROUND AND OBJECTIVE:
To evaluate the safety and bioavailability of complete and half-dose of intravitreal ziv-aflibercept (IVZ) in an experimental model.

MATERIALS AND METHODS:
Thirty-two eyes of 16 male rabbits received one IVZ injection under anesthesia and the operating microscope. All right and left eyes received 1,250 μg/0.05 mL and 625 μg/0.05 mL of ziv-aflibercept, respectively. Then, rabbits were randomly allocated to four groups (four rabbits in each group). The rabbits were euthanized at predesignated intervals (at 24, 168, 336, and 720 hours), and the eyes were enucleated. Indirect ophthalmoscopy, vitreous sampling, and electrophysiological recordings were obtained before euthanization. Histological examination was performed after enucleation. Vitreous samples were evaluated by enzyme-linked immunosorbent assay to measure the concentration of aflibercept.

RESULTS:
No serious drug-related ocular inflammation and toxicity or systemic adverse events were identified. Electroretinogram findings showed no significant difference to the baseline measurements. Remaining vitreal concentrations of ziv-aflibercept injection for the 625 μg/mL group were 416 μg/mL, 349 μg/mL, 124 μg/mL, 41.2 μg/mL, and 18.1 μg/mL (± 10 μg/mL) and for the 1,250 μg/mL group were 833 μg/mL, 737 μg/mL, 284 μg/mL, 87.3 μg/mL, and 38.2 μg/mL (± 10 μg/mL), at zero, 24, 168, 336, and 720 hours after injection, respectively. The vitreous concentration of aflibercept was analyzed by one-compartment model. The area under curve from time 0 to the end point (AUC last) was 147,637 hours × μg/mL for the complete dose group (1,250 μg/0.05mL) and 68,498 hours × μg/mL for the half-dose group (625 μg/0.05 mL). The assessed vitreous half-life of ziv-aflibercept was 113 hours in both groups.

CONCLUSIONS:
IVZ proved to be safe and well tolerated, even in the complete dose group. It seems to be a cost-effective therapeutic option for the treatment of retinal vascular diseases. However, the long-term safety and efficacy of intravitreal ziv-aflibercept remain unknown.

[
Ophthalmic Surg Lasers Imaging Retina
. 2019;50:785–790.]
OCTA: A Practical Method of Image Averaging Using Adobe Photoshop Software
Authors: Mikhail Mirriam , Jiang Shangjun , Hahn Paul , Orlin Anton , Rao Rajesh C. , Choudhry Netan 
Published: December 2019

BACKGROUND AND OBJECTIVE:
To describe a method for averaging ocular coherence tomography angiography (OCTA) images using a commercially available photo editing software: Adobe Photoshop CC 2017.

PATIENTS AND METHODS:
This single-center study assessed the feasibility of using Adobe Photoshop as an OCTA image averaging tool. Three 3.0 mm × 3.0 mm OCTA images from each eye were obtained using commercially available OCTA devices. Captured OCTA images were exported in high-resolution TIFF format, imported as an image stack, aligned using an automated function, and averaged by creating a Smart Object using Photoshop CC 2017 software. In conjunction with qualitative assessment, the main outcome of the study was image grader preferences with respect to clarity of the foveal avascular zone (FAZ), blood vessel delineation, and the ability to identify abnormal vasculature.

RESULTS:
After removing OCTA scans with significant image distortion, 25 sets of images were included in the analysis. Adobe Photoshop CC 2017 successfully aligned and averaged all images of the superficial and deep retinal plexuses that contained a minimum 40% overlap. Three independent retinal specialists found the averaged images to be slightly or definitely preferable to the original 87%, 89%, and 69% of the time with respect to clarity of the FAZ, clarity of blood vessel delineation, and the ability to identify abnormal vasculature, respectively.

CONCLUSIONS:
Adobe Photoshop CC 2017 is an excellent tool for image averaging, producing high-quality resulting OCTA images. As an easily accessible software, Photoshop has the potential for use in a diversity of pathological conditions.

[
Ophthalmic Surg Lasers Imaging Retina
. 2019;50:802–807.]
Concussion Recovery Timeline of High School Athletes Using A Stepwise Return-to-Play Protocol: Age and Sex Effects
Authors: Tamura Kaori , Furutani Troy , Oshiro Ross , Oba Yukiya , Ling Ayaka , Murata Nathan 
Published: December 2019

ContextImplementation of a stepwise return-to-play (RTP) protocol has become the standard management strategy for high school athletes to ensure a safe RTP after concussion. The detailed characteristics of the recovery timeline throughout the steps of an RTP protocol have not been delineated among the adolescent population.ObjectiveTo investigate the days spent in each step of the stepwise RTP protocol in an adolescent population and examine the effects of age and sex on recovery time.DesignCross-sectional study.SettingLocal schools.Patients or Other ParticipantsStudent-athletes from 57 schools.Intervention(s)A total of 726 patients with concussion (age = 15.5 ± 1.2 years, males = 454, females = 272) were included. The 7-step RTP protocol consists of the following steps: (1) complete cognitive rest, (2) full return to school, (3) light exercise, (4) running progression, (5) noncontact training drills and weight training, (6) full-contact practice or training, and (7) return to game play. The data were obtained by certified athletic trainers as a part of the statewide standardized concussion-management protocol.Main Outcome Measure(s)Days spent in steps 0 to 6 as well as a breakdown of days by sex and age.ResultsThe average total RTP days were 20.2 ± 13.9. Half of this time was spent in the return-to-school phase (steps 2–3: 10.2 ± 10.0 days). Compared with 17-year-old participants, younger participants (age = 14–16 years) took 3 or 4 days longer to start step 3 and to reach step 6 (P &lt; .05). Females took longer to reach step 6 than males (21.6 ± 15.5 versus 19.3 ± 12.7 days) because they took longer to reach step 3 (14.7 ± 11.4 days) than males (13.0 ± 10.0 days; P &lt; .05).ConclusionsOur study provides an estimated stepwise concussion recovery timeline for adolescent student-athletes. Clearance to start step 3 was the benchmark for the recovery timeline, as the duration of the exercise portion of the protocol was consistent across the age and sex groups.
Single-Session Video and Electromyography Feedback in Overhead Athletes With Scapular Dyskinesis and Impingement Syndrome
Authors: Du Wan-Yu , Huang Tsun-Shun , Chiu Yuan-Chun , Mao Szu-Jieh , Hung Li-Wei , Liu Mei-Fang , Yang Jing Lan , Lin Jiu-Jenq 
Published: December 2019

ContextSubacromial impingement syndrome (SIS) is associated with scapular dyskinesis, or imbalanced scapular muscle activity. Evidence has shown that feedback can improve scapular control in patients with SIS. However, it is unknown whether real-time video feedback or electromyography (EMG) biofeedback is optimal for improving scapular kinematics and muscle activity during a functional task.ObjectiveTo compare the effects of video and EMG feedback sessions on absolute muscle activity (upper trapezius [UT], lower trapezius [LT], serratus anterior), muscle balance ratios (UT/LT, UT/serratus anterior), and scapular kinematics (anterior-posterior tilt, external-internal rotation, upward rotation) in SIS participants during arm elevation and lowering.DesignRandomized controlled clinical trial.SettingResearch laboratory.Patients or Other ParticipantsOverhead athletes who were diagnosed with SIS and who also exhibited scapular dyskinesis (N = 41).Main Outcome Measure(s)Three-dimensional kinematics and EMG were recorded before and after feedback training.ResultsLower trapezius muscle activity increased (4.2%–18%, P &lt; .011) and UT/LT decreased (0.56–1.17, P &lt; .013) in the EMG biofeedback training group as compared with those in the video feedback training group. Scapular upward rotation during arm elevation was higher in the video group than in the EMG group after feedback training (2.3°, P = .024).ConclusionsThe EMG biofeedback improved muscle control and video feedback improved the correction of scapular upward rotation in patients with SIS.Trial Registration NumberClinicalTrials.gov: NCT03252444.
Role of Cresp® in the management of chemotherapy-induced anemia in cancer patients: A real-world clinical practice audit
Authors: Biswas Ghanshyam , Pandey Avinash , Ghadyalpatil Nikhil , Lokeshwar Nilesh , Thomas Boben , Ramesh Anita , Arora Yogesh , Dodagoudar Chandragouda , Naik Vibha , Joshi Ashish , Ghosh Indranil , Roy Rakesh , Kunjahari Medhi , Singh Tejinder , Satya Palanki Dattatreya , Hingmire Sachin , Parikh Purvish M. 
Published: December 2019

Abstract
Introduction: Anemia is a common, underestimated problem in cancer patients receiving myelosuppressive chemotherapy and has significant adverse effect on the quality of life and outcome. Darbepoetin has been shown to be effective in this setting, but controversy surrounds it actual use. Methods: We analyzed prospectively collected clinical practice data of patients receiving darbepoetin in a real-world setting for this retrospective audit. Patients with baseline hemoglobin (Hb) of <11 g/dl were included in this analysis. Their medical records were audited using a predetermined 35-point pro forma. Results: There were a total of 274 patients with advanced cancer receiving myelosuppressive chemotherapy who had baseline Hb <11 g/dl and who were given darbepoetin. Head-and-neck squamous cell carcinoma, lung cancer, and breast cancer were the most common cancers. Their median baseline Hb was 8.9 g/dl which rose to 11.2 g/dl at the end of commenced therapy, along with improved symptomatology. There were no new toxicities, and only two patients required discontinuation of darbepoetin due to toxicity. Conclusion: Darbepoetin is safe and effective in the prevention and management of anemia among patients receiving myelosuppressive chemotherapy.
Reliability of conventional Papanicolaou smear in diagnosing bacterial vaginosis among women with clinical genital infection
Authors: Anand Kavita Vivek , Pimple Sharmila Anil , Mishra Gauravi A. , Sahare Rupali V. , Pathuthara Saleem , Deodhar Kedar K. , Shastri Surendra S. 
Published: December 2019

Abstract
Objective: Bacterial vaginosis (BV) is a common reproductive tract infection (RTI) reported among Indian women. BV can influence the persistence of high-risk oncogenic human papillomavirus, a causative factor for cervical cancer. BV and cervical cancer are major public health issues in a developing country like India. It becomes important for a resource-constrained country like India with poor healthcare access to implement control measures to screen and treat RTI in an attempt to prevent the risk for cervical cancer. Papanicolaou (Pap) smear is an established screening tool for cervical cancer and the diagnosis of RTIs, forms a part of its evaluation. The present study explores the validity of conventional Pap smear in diagnosing BV. Methodology: Pap smear and Gram stain smear were collected for 254 women with clinically evident cervicitis/cervicovaginitis (genital infection). Using the Nugent score on Gram stain as a gold standard, we determined the sensitivity and specificity of Pap smear to diagnose BV. Results: The overall prevalence of BV in the study population was 44% using the Nugent score. Pap smear showed sensitivity and specificity of 70.9%. (CI- 61.5% - 79.2%) and 56.8% (CI – 48.2%–65.2%), respectively. The positive predictive value of Pap smear to diagnose BV was 56.5% (CI – 47.8%–64.9%), and the negative predictive value was 71.2% (CI – 61.8%–79.4%). Conclusion: In the present study, conventional Pap smear demonstrates good accuracy to detect BV. Pap testing for cervical cancer screening can additionally serve as an effective screening tool for diagnosing BV among women with genital infection in healthcare settings.
Lymph node metastasis in extremity chondrosarcomas
Authors: Kurisunkal Vineet , Gulia Ashish , Ajay Puri , Rekhi Bharat 
Published: December 2019

Abstract
Bacground: Primary bone sarcomas mainly metastasize through haematogenous route and rarely through lymph nodes due to paucity of lymphatic channels in the bone (1). Nodal spread in chondrosarcoma is extremely rare and there are two reported cases in literature including one previously published by our institute (3, 5). Aims and Objectives: We present a series of chondrosarcoma cases (primary tumour located in the scapula, proximal femur, proximal humerus and pelvis), presenting with lymph node metastasis, treated at our institute. We assessed the oncological outcome of these cases and the impact of nodal metastasis on survival. Materials and Methods: Between January 2006 and December 2015, 243 patients of extremity and pelvic chondrosarcoma were operated at our institute. These cases were retrieved from a prospectively maintained database. Four (1.6%) of these patients developed lymph node metastasis. Clinical and radiological details of these cases were retrieved from electronic medical records and case files. Histopathology of the primary chondrosarcoma lesion and nodal metastasis was reconfirmed by a pathologist specializing in sarcomas. Conclusion: Lymph node metastasis though extremely rare in primary osseous chondrosarcoma, definitely affects their survival adversely. The rarity of the occurrence of lymph node metastasis in primary osseous tumors, especially chondrosarcoma highlights the need for multi institutional studies to pool knowledge and evaluate the prognostic significance and etiopathogenesis of lymph node metastasis in primary bone chondrosarcoma.
EMBEDDED PARTICULATE BIOMATERIALS AS DIELECTRIC FILLERS IN ELECTROACTIVE NATURAL RUBBER COMPOSITES
Authors: Bunprasert Poramin , Tangboriboon Nuchnapa 
Published: December 2019

ABSTRACT
Both eggshell and eggshell membrane are potential alternative dielectric biomaterials because of their inorganic and organic matter contents, respectively. Adding eggshell or eggshell membrane into natural rubber compounds made using the sulfur curing system has many advantages such as flexibility, ease of formation, ability to operate under large strains and shape conformability, lightweight, and low cost of production. The results indicated that the natural rubber composite had a rubberlike characteristic and good elasticity. Both the eggshell and eggshell membrane acted as a dispersed-phase or dielectric filler that can absorb and store additional stress effects, resulting in fast curing and increasing crosslink density. Under a variable electrical field, eggshell and eggshell membrane particles induced dipolar moments and led to interparticle interactions that increased the storage modulus response substantially by nearly two orders of magnitude at 1.5 kV/mm. The obtained natural rubber composites can contribute toward more effective polarization and hence stronger electrostatic interactions between the embedded particles, resulting in a fast deflection response due to the dielectrophoresis force generation at low electrical field strengths of 300 and 350 V/mm for eggshell and eggshell membrane, respectively. The additional advantage of eggshell waste utilization is welcome as a means of reducing global climate warming and adding value to eggshell waste.