bluuebunny/crossref_metadata_2025_split huggingface dataset:
DRUG UTILIZATION EVALUATION OF BENZODIAZEPINES IN A TERTIARY CARE HOSPITAL
Authors: RAMA P. , MONISHA R. , PAUL SUSAN VARGHESE , SCARIA VARSHA ELSA , JANANI P. , PERUMAL SANTHOSH 
Published: November 2019

Objective: To assess the rationale use of benzodiazepines among various departments in a multi-speciality hospital.
Methods: A prospective study was conducted with a sample size of 200 for a period of six months. Data was collected from patients based on inclusion and exclusion criteria. Naranjo Adverse Drug Reaction Probability Scale and Drug Interaction Probability Scale (DIPS) were used as a study tool to measure the causality of adverse drug reactions and drug interactions. Based on the dosage of various benzodiazepines DDD was calculated and compared with WHO Anatomical Therapeutic Chemical (ATC) classification Defined Daily Dose (DDD).
Results: BZD’s were mostly prescribed in males (74.5%) and married patients (86.5%) were more exposed to benzodiazepines compared to others. Lorazepam (70.1%) was found to be the most commonly used drug, mainly prescribed for sedation, followed by anxiety. DDD was calculated and majority of patients had DDD in accordance with WHO standard. Based on cost analysis, Clobazam was found to be the high cost and Lorazepam being the low-cost drug. The results of drug utilization evaluation of benzodiazepines study were compiled and reported to the respected department physician and their feedback was collected.
Conclusion: The study showed a rational utilization of benzodiazepines and the negative outcomes of BZDs can be reduced by providing drug-related information to the prescribers and consumers.
THE REASONS ACUTE STROKE PATIENTS NOT RECEIVING THROMBOLYSIS IN AN INDONESIAN REFERRAL HOSPITAL
Authors: RASYID AL , HARRIS SALIM , KURNIAWAN MOHAMMAD , MESIANO TAUFIK , HIDAYAT RAKHMAD , Rilianto Beny , SHOLEHA RATU AZIZAH 
Published: November 2019

Objective: The aim of this study was to identify reasons acute stroke patients did not receive thrombolysis despite meeting Code Stroke activation criteria in Cipto Mangunkusumo General Hospital during November 2015 until February 2019.
Methods: This study retrospectively collected data of adult (aged>18 y old) acute stroke patients admitted to Cipto Mangunkusumo General Hospital from November 2015 to February 2019 who met criteria for Code Stroke activation but did not undergo thrombolysis. Patient’ data were collected from Code Stroke Registry of Cipto Mangunkusumo General Hospital.
Results: There were 518 acute stroke patients who had Code Stroke activated in Cipto Mangunkusumo General Hospital from November 2015 to February 2019. 76.3% of acute stroke patients did not receive thrombolytic therapy (n=395). Hemorrhage on computed tomography (CT) scan was the most common reason patients did not receive thrombolysis. The following most common reasons were low or improved National Institutes of Health Stroke Scale (NIHSS) score, family refusal, and exceedance of time window.
Conclusion: Hemorrhage on CT scan was the most common reason patients did not receive thrombolysis following by low or improved NIHSS score, family refusal, and exceedance of time window.
PENGARUH KEMANDIRIAN BELAJAR TERHADAP KEMAMPUAN PENALARAN MATEMATIS SISWA SMP PADA MATERI PERBANDINGAN
Authors: Zannati Ghina Nurul , Fitrianna Aflich Yusnita , Rohaeti Euis Eti 
Published: November 2019

This study aims to investigate how significant the ability of mathematical reasoning is influenced by the independence of learning on comparative materials. The method used in this study is correlational method with quantitative approach. The population in this study were students of SMP / MTs in Kota Cimahi and the samples were 30 students of MTs Al-Musyahadah Cimahi. The instrument in this research is a test of 6 questions about comparison of mathematical reasoning ability and 32 scale statements of scale self-learning. The data analysis technique, which was applied, is the prerequisite analysis test in the form of normality test and correlation test. The results of this study concluded that students' mathematical reasoning ability on comparison material is positively influenced by learning independence 57.33% and the remaining 42.67% is determined by other factors. AbstrakPenelitian ini bertujuan untuk melihat pengaruhi kemandirian belajar terhadap kemampuan penalaran matematis pada materi perbandingan. Metode dalam penelitian ini menggunakan metode korelasi dengan pendekatan kuantitatif. Populasi dalam penelitian ini adalah siswa SMP/MTs di Kota Cimahi dan sampelnya sebanyak 30 orang di MTs Al-Musyahadah Cimahi. Instrumen dalam penelitian ini berupa tes kemampuan penalaran matematis sebanyak 6 butir soal materi perbandingan yang sudah divalidasi serta diuji cobakan dan skala kemandirian belajar sebanyak 32 skala pernyataan. Teknik analisis data yang digunakan yaitu berupa uji normalitas dan uji kolerasi. Hasil penelitian ini memperoleh kesimpulan bahwa, kemampuan penalaran matematis siswa pada materi perbandingan dipengaruhi positif oleh kemandirian belajarnya 57,33% dan sisanya 42,67% ditentukan oleh faktor lain. Kata Kunci: Kemampuan Penalaran Matematis, Kemandirian Belajar
PENGARUH SELF CONFIDENCE DAN SELF EFFICACY TERHADAP KEMAMPUAN BERPIKIR KREATIF MATEMATIS SISWA SMP
Authors: Septiani Tamia , Hudanagara Muhammad Abdussalam , Hendriana Heris , Anita Ika Wahyu 
Published: November 2019

Untuk pencapaian berpikir kreatif matematis, diperlukan sebuah aspek penting yang harus dimiliki oleh siswa yaitu self confidence dan self efficacy yang baik, karena dalam self confidence dan self efficacy terdapat indikator-indikator yang dapat mendukung tujuan tersebut. Penelitian ini bertujuan untuk mengetahui secara mendalam tentang terdapat pengaruh self confidence dan self efficacy secara simultan terhadap kemampuan berpikir kreatif matematis siswa SMP. Populasi dalam penelitian ini adalah siswa SMP di Kota Cimahi. Instrumen dalam penelitian ini berupa tes kemampuan berpikir kreatif matematis sebanyak enam soal, dan angket self confidence dan self efficacy siswa. Metode dalam penelitian ini menggunakan metode regresi ganda. Hasil penelitian ini menunjukan terdapat pengaruh self confidence dan self efficacy terhadap kemampuan berpikir kreatif matematis siswa SMP.
PENGARUH SELF REGULATED LEARNING TERHADAP KEMAMPUAN BERPIKIR KREATIF MATEMATIS SISWA SMA
Authors: Mauludin Asep , Nurjaman Adi 
Published: November 2019

Penelitian ini bertujuan untuk menelaah dan mendeskripsikan pengaruh self regulated learning terhadap kemampuan berpikir kreatif matematis siswa SMA Desain penelitian ini adalah survey. Untuk mendapatkan data hasil penelitian digunakan instrumen berupa tes kemampuan berpikir kreatif dan skala self regukated learning siswa. Populasi penelitian ini adalah seluruh siswa SMP Negeri 13 Jakarta dengan sampel penelitian siswa kelas XI sebanyak 31 siswa. Analisis data dilakukan secara kuantitatif. Analisis kuantitatif dilakukan terhadap data kemampuan berpikir kreatif dan data self-concept. Instrumen yang digunakan sebanyak 5 soal tes kemampuan berpikir kreatif dan 30 pernyataan mengenai self regulated learning. Dalam perhitungan ujicoba intrumen menggunakan program axcell 2010 dan perhitungan statistik menggunakan SPSS 17. Hasil penelitian menunjukkan bahwa self regulated learning mempengaruhi kemampuan berpikir kreatif matematis siswa.
ANALISIS KARAKTERISTIK LEARNING OBSTACLE SISWA SMP DALAM MENYELESAIKAN SOAL BANGUN DATAR
Authors: Rismawati Yunita , Nurlitasari Lita , Kadarisma Gida , Rohaeti Euis Eti 
Published: November 2019

Tujuan Penelitian ini adalah untuk menganalisis karakteristik learning obstacle yang terjadi pada siswa SMP saat mengerjakan soal kemampuan komunikasi matematika dengan materi bangun datar. Jenis learning obstacle yang difokuskan pada penelitian ini adalah ontogenic obstacle, didactical obstacle dan epistemologi obstacle. Metode Penelitian ini adalah kualitatif deskriptif dengan 3 sampel siswa (dari kemampuan rendah, sedang dan tinggi) dari salah satu sekolah di Kota Cimahi, instrumen penelitian ini berupa seperangkat tes pada materi bangun datar dan pedoman wawancara. Hasil dari penelitian ini diperoleh bahwa karakteristik learning obstacle yang terjadi kebanyakan epistemologi obstacle yaitu keterbatasan koteks yang dimiliki siswa, sedangkan didactical obstacle hanya sebagian kecil yang mengalaminya dan tidak ada siswa yang mengalami ontogenic obstacle dalam menyelesaikan soal
KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA SMP KELAS VIII PADA MATERI SISTEM PERSAMAAN LINIER DUA VARIABEL DENGAN PENDEKATAN OPEN ENDED
Authors: Mulyowati Nuni , Afrilianto Muhammad , Rohaeti Euis Eti 
Published: November 2019

The objective of this research is to analyze theimprovement of problem solving ability from students at VIII grade on material of two variables linear equationssystem thtough open ended approach. This research uses Classroom Action Reserch. The method of the research is descriptive. The research is conducted to VIII H grade student of SMP Negeri 9 in academic year 2017/ 2018 which consist of 40 students. The instrument is the testof students’ mathematical problem solving ability, cycle test I and II after giving action. The result aspectof this research shows that the aspect of students’ mathematical problemsolving ability increased, it can be seen from the result of the test, many studentsachive above beverage score (KKM).Bsed on indicator, it concludes that students’ problem solving ability at VIII H grade of SMP Negeri 9on material of two variables linear equations system can be improved through open ended approach
PENERAPAN PENDEKATAN PEMBELAJARAN DISCOVERY LEARNING TERHADAP SELF CONFIDENCE SISWA SMP DI KABUPATEN PURWAKARTA
Authors: Marjani Lulu , Rinaldi Aris , Hendriana Heris , Anita Ika Wahyu 
Published: November 2019

This research is aims to improve learning approach Discovery learning and Self Confidence to junior high school students on two linears equation. The research was conducted in one of Junior High School in Purwakarta. understanding of students in understanding the concept of system of linear equations of two variables is still very low because students emphasized the use of formulas and routine exercises. because of that, the researcher seeks to apply learning approach Discovery Learning to stundents Self Confidence. this research uses classroom action research method which is implemented through two cycles consisting of one cycle on one meeting. the instrument used is the observation sheet, interview, preliminary tests and tests each cycle. In the preliminary tests showed that confidence in the mastery of the concept of linear equations of learners is still very low. On the cycle of a stundent's activities is listening explanation about the matter of concept of linear equation of two variable, identifiying, collecting information, and solving the problems that the teacher provides. On the one cycle many students are still confused in understanding the two-variable linear equation material and their confidence are still very low. In the second cycle the students has improved in understanding the concept of linear equations of two variables and has a good selfconfidence. The result of this research showed that the used of learning approach Discovery Learning on stundent's self confidence on understanding the concept of linear equations of two variables has increased.
PENERAPAN PENDEKATAN PROBLEM BASED LEARNING TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA SMP
Authors: Yulianti Ai Solihat , Sugandi Asep Ikin 
Published: November 2019

This study aims to to know the achievement of the ability of the solution of the problems a useful or valuable junior high school students who studying used the the problem of fee-based learning with that uses ordinary learning , with material used in this research is a circle of class VIII junior high school semester the even . The methodology that was used is quantitative, who is in the form of experiments in support with the data the result of pretes and postes .Population in this research is junior high school students class viii at west bandung. Were selected from research is 34 of the students of experimentation and 32 of the students of control in the academic year 2017 / 2018 .An instrument that is used is math tests the ability of the solution of the problems . Processing the results of the data were analyzed using application ibm spss statistics version 22. Processing analysis data using test normality followed by test of homogeneity then to test t-hitung on the data pretes.While in data postes test normality then to test the average that is mann-whitney test. Based on analysis of the that has been done , obtained that the achievement of the ability problem solving math junior high school students which adopting the problem based learning better than use learning ordinary.
HUBUNGAN SELF CONFIDENCE TERHADAP KEMAMPUAN BERFIKIR KREATIF MATEMATIS SISWA MTs
Authors: Masfufah Siti Hafsah , Winarsih Puput , Kadarisma Gida 
Published: November 2019

This research to find out in depth about the relationship of self confidence to the ability to think creatively mathematically MTs students. The population in this research is MTs in Cimahi City. Instrument in this research in the form of description of ability of mathematical creative thinking as much as 5 item, and self confidence questionnaire of student. Methods in this research using correlational research methods. The result of this research shows that there is a correlation (r) value on Person Corellation between self confidence with students’ mathematical creative thinking ability is 0,597**. Form these results show the level of relationships that are classified and indicate the direction of a positive relationship.
ANALISIS SELF CONFIDENCE SISWA KELAS X HT 3 SMK SANGKURIANG 2 DALAM PEMBELAJARAN MATEMATIKA
Authors: Masruroh Ani Ainun , Faturohman Yusuf , Hidayat Wahyu , Rohaeti Euis Eti 
Published: November 2019

SMA/SMK was the last high school before going to College. High school students/CMS are at the stages of adolescent age. The World Health Organization (1974) set the age limit of 10-20 years as a teenage limit (Sarwono,2008). Based on a review of the theory of progression, the age of adolescence is a time of onset of rapid changes, such as physical changes, changes in fundamental aspects of cognitive, emotion, social and achievement. Teens experiencing instability from time to time and they try to adopt new behavior from the previous development phases (Soetjiningsih,2004). Teens often have problems because of her unstable and still has not been formed in cooked. The attitude of the labile affected the level of confidence, such as the fearless try and there are times when his minder with her own.
Brecha digital, idioma inglés y su vínculo con la comprensión lectora en español
Authors: Herrera Rivas Hiram , Roque Hernández Ramón Ventura 
Published: November 2019

Para toda universidad es de gran importancia la detección oportuna de factores de éxito académico con la finalidad de generar estrategias adecuadas de tutoría que contribuyan con la finalización de estudios en tiempo y forma. El objetivo de esta investigación fue profundizar en el entendimiento de la primera brecha digital, el dominio del idioma inglés y la relación de ambos con la comprensión lectora en español de los alumnos de nuevo ingreso en la Universidad Politécnica de Victoria (UPV). Se utilizó un diseño de investigación cuantitativo, relacional y retrospectivo, en donde se analizaron los resultados del Examen Ceneval Exani-II que se aplicó a los alumnos de nuevo ingreso de dicha institución, ubicada en Tamaulipas, México, en los años 2015, 2016 y 2017.
Se realizó un análisis unifactorial con cuatro grupos de estudio creados a partir de los datos. Esto permitió identificar una tendencia de aumento de la comprensión lectora ante la presencia del acceso a internet en casa y de un dictamen favorable del idioma inglés. En una segunda fase, se procedió con un análisis con dos factores con el que se pudo observar cada variable de manera independiente y la interacción de ambas. A través de las pruebas se pudo demostrar estadísticamente en todos los años que el dominio del idioma inglés incide positivamente en la comprensión lectora en español (pruebas Scheirer-Ray-Hare, p = 0.0). También se observó una tendencia favorable en la comprensión lectora en español en los alumnos que tienen internet en casa (año 2017, prueba Scheirer-Ray-Hare, p = 0.0). De esta manera, los alumnos que tienen internet en casa y que obtuvieron un dictamen satisfactorio en el idioma inglés obtuvieron las puntuaciones más altas, mientras que los alumnos sin este servicio en casa y con un dictamen insatisfactorio en inglés tuvieron las puntuaciones más bajas (pruebas Kruskal-Wallis, p = 0.0). Estos resultados muestran que existen estudiantes de nuevo ingreso en la UPV que inician sus estudios universitarios en desigualdad de condiciones con los demás. Es preocupante que aún hoy en día existan estudiantes sin acceso a internet en casa y sin un dominio satisfactorio la lengua inglesa, pues son condiciones que reducen sus probabilidades de éxito académico. Es necesario reflexionar sobre la desigualdad que afecta a estos alumnos y las maneras en que se puede mejorar esta situación desde el interior de la misma universidad.
Análisis comparativo de la implementación de la educación ambiental en programas de licenciatura de tres universidades
Authors: Bedolla Solano Ramón , Miranda Esteban Adriana , Sánchez Adam Oscar , Bedolla Solano Juan José 
Published: November 2019

La educación ambiental (EA) surge a partir de la gran preocupación en todo el mundo ante la crisis ambiental y es parte de un proceso que promueve competencias socioambientales. La universidad representa un espacio adecuado para introducir saberes ambientales en el currículo; de tal manera que las competencias específicas y de egreso del proyecto educativo sean complementadas ambientalmente. El objetivo de esta investigación fue realizar un análisis comparativo sobre la integración de la EA en programas de licenciatura de tres universidades: Universidad Autónoma de Guerrero (México), Universidad Regional de Blumenau (Brasil) y Universidad Metropolitana Nelson Mandela (Sudáfrica).
Es una investigación mixta con enfoque comparativo y descriptivo. Se realizó en el periodo 2015-2017. Se aplicó una encuesta a profesores y a estudiantes de los programas objeto de estudio, una entrevista a integrantes de los programas de México y Sudáfrica y cuestionarios de opinión a informantes clave del currículo de los programas de la universidad de Brasil, y se revisaron algunos documentos oficiales. Las dimensiones consideradas en los instrumentos y técnicas fueron con base en los siguientes elementos: percepción de la problemática ambiental, la relación que existe entre la EA y el currículo, las competencias ambientales que promueven docentes y forman estudiantes y la revisión de reglamentos que establecen la integración de la EA en el plan de estudio.
El resultado de la encuesta evidenció, entre otras cosas, que estudiantes y profesores de los programas educativos de México cuentan con un menor grado de percepción de la problemática ambiental en comparación con los profesores de los programas de las otras dos universidades. De la información proporcionada por informantes claves se dedujo que dos programas de la universidad de México y los dos de Brasil contemplan de alguna forma la EA. Sin embargo, en la primera es en menor proporción y de manera disciplinar; en la segunda es en mayor proporción: su integración es de manera transversal y está en proceso. En el programa de Sudáfrica, la EA no figura. En cuanto a los documentos oficiales, los programas de México y Brasil cuentan con un sustento que respalda la integración de la EA; en el caso de Sudáfrica no se cuenta con un documento oficial.
La incorporación de la EA en los programas de las universidades se vislumbra cuando se inmiscuye la dimensión ambiental en el currículo de manera disciplinar, transversal o de otro modo. En consecuencia, se desarrollan diversas tareas para preservar el medio y buscar la sustentabilidad.
Water Extract of Tamarix gallica L. as effective Agents against C6 and HeLa tumor cell lines
Authors: Fellah Ouroud , Hameurlaine Samir , Djermane Mohamed , Tahar Wafa , Altun Muhammed , Gherraf Noureddine , Zellagui Amar , Akkal Salah , Abidi Abdenabi , Tahar Ali , Demirtas Ibrahim , SahinYaglioglu Ayse , Nieto Gema 
Published: November 2019

Abstract
The aerial parts of Tamarix gallica L. taken from three different climatic stages in Algeria (Oum El Bouaghi: Semi-arid, ElTaref: Humid, and Ouargla: Arid) were extracted using boiling distilled water. The crude extracts were subjected to total phenolics and flavonoids quantifications in addition to anti-proliferative assessment against two tumor cell lines namely rat brain tumor (C6) and human cervix carcinoma (HeLa) using BrdU (bromo-deoxyuridine) ELISA(Enzyme-linked immune-sorbent assay) and xCELLigence assay. The total phenolics yield was found to range between 16.14 and 39.32 mg GAE (Gallic acid equivalent)/g of extract and a flavonoids yield ranging between 16.51 and 20.35 mg QE(quercetin equivalent)/g of extract. The various phenolics were identified using HPLC-TOF/MS to highlight hesperidin and rosmarinic Acid as major components. Moreover, the extracts exhibited different levels of antitumor potency against C6 and HeLa cell lines depending upon the climatic stage and the concentration. A good cytotoxic effect was recorded with the species collected from the humid region at 250 μg/mL. On the contrary, the other extracts revealed a weak activity for both tests.
Chemical Composition of the Essential Oil of Aerial Parts of Thymus ciliatus (Desf.)
Authors: Achoub Hanane , Zaiter Lahcene , Benayache Fadila , Benayache Samir , Chalchat Jean Claude , Chalard Pierre , Figueredo Gilles , Akkal Salah 
Published: November 2019

Abstract
The essential oil of the aerial parts of Thymus ciliatus (Desf.) belonging to the Lamiaceae family, was obtained by steam distillation and analyzed by GC-FID and GC-MS. 75 components were identified corresponding to 95.57% of the total oil. The major constituents of the oil were: elemol (6.80%), carvacrol (5.86%), γ-muurolene (5.18%), β-sesquiphellandrene (5.09%), bicyclogermacrene (5.04%), β-pinene (4.49%) and curcumene (4.20%), together with other compounds at relatively low levels: 1,8-cineol (3.66%), β-eudesmol (2.92%), β-bisabolene (2.81%), β-silinene (2.75%), camphor (2.64%), germacrone (2.34%), α-zingiberene (2.12%), δ-cadinene (2.08%), caryophyllene oxide (1.90%), spathulenol (1.88%), □-caryophyllene (1.88%), ar-turmerone (1.79%), α-pinene (1.52%), limonene (1.52%), selina-4,11-diene (1.46%), curzerenone (1.41%), germacrone B (1.37%), bornyl acetate (1.31%), β-farnesene (1.28%), borneol (1.23%), myrtenal (1.16%), zingiberenol (1.15%) and sabinene (1.13%). These results differ from those of previous studies reported on this species collected from other regions of Algeria and Morocco.