bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of semi-annual therapy of an extended-release injectable moxidectin suspension and oral doxycycline in Dirofilaria immitis naturally infected dogs
Authors: Alberigi Bruno , Fernandes Julio I. , Paiva Jonimar P. , Mendes-de-Almeida Flavya , Knackfuss Fabiana , Merlo Alexandre , Labarthe Norma 
Published: October 2020

AbstractBackgroundDirofilaria immitisis a life-threatening nematode spreading globally. Arsenical treatment is currently recommended for removal of adult worms. However, arsenical treatment is not available in some countries, and there are dogs that cannot tolerate the rapid kill of adult worms; therefore, alternative adulticide slow-kill treatments are needed. Criticisms against the use of these alternative protocols include the potential for allowing disease to progress and for the development of ML-resistant worms.MethodsThe efficacy of a protocol that includes semi-annual doses (i.e. every 6 months) of commercially available extended-release injectable moxidectin suspension (ProHeart®SR-12) with 30-day oral administration of doxycycline was studied in 20 dogs with naturally occurringD. immitisinfections. Each dog received treatment with ProHeart®SR-12 (0.5 mg moxidectin/kg) by subcutaneous injection and oral doxycycline (10 mg/kg/bid × 30 days) every 6 months until two consecutive negative antigen test results were obtained. Pulmonary and cardiac evaluations were performed by radiographic and echocardiographic parameters. Physical examinations, complete blood counts, clinical chemistry profiles, microfilariae and antigen tests were performed periodically.ResultsAt enrollment, all dogs were positive forD. immitisantigen and 18 were microfilaremic. On day 30, microfilaremia counts decreased, and all dogs became amicrofilaremic by day 150. On day 180, 11 dogs were antigen-negative, and 7 more became negative by day 360. The two remaining antigen-positive dogs converted to negative by day 540 or 810. All antigen tests performed 180 days after the first negative test were negative. There was no decline in cardiac performance of the dogs throughout the study. Overall, pulmonary clinical conditions, presence of worms by echocardiography, and enlargement of caudal and main pulmonary arteries improved after treatment. Physical examinations, complete blood count results, and clinical chemistry profiles were within normal reference values. Respiratory conditions were improved, no damage to the heart was observed, and the treatment protocol was well tolerated by the animals.ConclusionsThis alternative adulticide treatment was efficacious and well tolerated in naturally infected dogs. The injectable formulation provides the advantage of having veterinarians able to administer, monitor, and assess the efficacy and condition of the dog throughout the treatment and post-treatment periods.
Evaluating the effects of behavior change training on the knowledge, confidence and skills of sport and exercise science students
Authors: Matthews James , Hall Amanda M. , Keogh Alison 
Published: October 2020

Abstract
Background
Behavior change interventions have the potential to have a transformative effect on the health of populations. Allied health professionals have a key role to play in delivering these interventions. However, traditionally undergraduate allied health professional programs have not had a behavior change focus. The aim of this study was to assess the effectiveness of a training program on sport and exercise science students’ knowledge, confidence and skills in the provision of behavior change support.

Method
A mixed method convergent design was used to address the research question. Fifteen sport and exercise science students took part in a training program consisting of seven 90-min weekly face to face group sessions. Student satisfaction with training methods was assessed. Pre-to-post training changes in students’ confidence and knowledge in the provision of behavior change support was evaluated. Delivery of behavior change support was assessed by an audio recorded role-play rated by an expert using the Health Care Climate Questionnaire, and an adapted version of the Communication Evaluation in Rehabilitation Tool. Students also completed a reflective assignment.

Results
Students were satisfied with the training. There were increases in students’ confidence and knowledge of certain behavior change components post-training but not behavior change techniques. Students delivered behavior change support in a broadly needs supportive manner. The reflective assignment showed that students found particular behavior change strategies difficult to implement.

Conclusion
It is feasible to train undergraduate students in particular components of behavior change support. Academic institutions should embed behavior change training into the allied health professional curriculum to ensure graduates are job ready with the knowledge, confidence and skills to support health related behavior change within the wider health system.
Dissimilarity of microbial diversity of pond water, shrimp intestine and sediment in Aquamimicry system
Authors: Zeng Shenzheng , Khoruamkid Sukontorn , Kongpakdee Warinphorn , Wei Dongdong , Yu Lingfei , Wang Hao , Deng Zhixuan , Weng Shaoping , Huang Zhijian , He Jianguo , Satapornvanit Kriengkrai 
Published: October 2020

AbstractThe Pacific white shrimp, with the largest production in shrimp industry, has suffered from multiple severe viral and bacterial diseases, which calls for a more reliable and environmentally friendly system to promote shrimp culture. The “Aquamimicry system”, mimicking the nature of aquatic ecosystems for the well-being of aquatic animals, has effectively increased shrimp production and been adapted in many countries. However, the microbial communities in the shrimp intestine and surrounding environment that act as an essential component in Aquamimicry remain largely unknown. In this study, the microbial composition and diversity alteration in shrimp intestine, surrounding water and sediment at different culture stages were investigated by high throughput sequencing of 16S rRNA gene, obtaining 13,562 operational taxonomic units (OTUs). Results showed that the microbial communities in shrimp intestine and surrounding environment were significantly distinct from each other, and 23 distinguished taxa for each habitat were further characterized. The microbial communities differed significantly at different culture stages, confirmed by a great number of OTUs dramatically altered during the culture period. A small part of these altered OTUs were shared between shrimp intestine and surrounding environment, suggesting that the microbial alteration of intestine was not consistent with that of water and sediment. Regarding the high production of Aquamimicry farm used as a case in this study, the dissimilarity between intestinal and surrounding microbiota might be considered as a potential indicator for healthy status of shrimp farming, which provided hints on the appropriate culture practices to improve shrimp production.
Therapeutic interventions in Australian primary care, youth mental health settings for young people with borderline personality disorder or borderline traits
Authors: O’Dwyer Nikki , Rickwood Debra , Buckmaster Dean , Watsford Clare 
Published: October 2020

Abstract
Background
This study aimed to investigate what therapeutic interventions were being applied by clinicians working with young people with a diagnosis of Borderline Personality Disorder or borderline traits in Australian primary mental health care settings. Given the current lack of evidence-based guidelines for treatment with this client population, investigating what is being implemented is needed. The study also aimed to determine whether the interventions clinicians are using are effective in reducing distress and increasing functioning for these clients.

Methods
Participant data came from the national minimum data set for headspace youth mental health centers across Australia. Young people’s data were included in the study if the young person was diagnosed with Borderline Personality Disorder or borderline traits during their first episode of care (N = 701). Clinician data that indicated the type of intervention used at each client session and outcome measures routinely captured were analyzed to determine interventions used and outcomes achieved.

Results
Results demonstrated that CBT was the most frequently used modality of intervention followed by supportive counselling and IPT, but that most clients received a variety of intervention types. There were no or only weak relationships between changes in outcomes and the amount of any type of intervention that was provided. No significant relationship was found with the amount of CBT a client received and changes in symptoms or functioning, despite being the most commonly employed modality.

Conclusions
The study highlights the need for evidence-based treatment guidelines for early intervention in young people with borderline personality disorder traits.
Real-time monitoring of traffic parameters
Authors: Khazukov Kirill , Shepelev Vladimir , Karpeta Tatiana , Shabiev Salavat , Slobodin Ivan , Charbadze Irakli , Alferova Irina 
Published: October 2020

AbstractThis study deals with the problem of rea-time obtaining quality data on the road traffic parameters based on the static street video surveillance camera data. The existing road traffic monitoring solutions are based on the use of traffic cameras located directly above the carriageways, which allows one to obtain fragmentary data on the speed and movement pattern of vehicles. The purpose of the study is to develop a system of high-quality and complete collection of real-time data, such as traffic flow intensity, driving directions, and average vehicle speed. At the same time, the data is collected within the entire functional area of intersections and adjacent road sections, which fall within the street video surveillance camera angle. Our solution is based on the use of the YOLOv3 neural network architecture and SORT open-source tracker. To train the neural network, we marked 6000 images and performed augmentation, which allowed us to form a dataset of 4.3 million vehicles. The basic performance of YOLO was improved using an additional mask branch and optimizing the shape of anchors. To determine the vehicle speed, we used a method of perspective transformation of coordinates from the original image to geographical coordinates. Testing of the system at night and in the daytime at six intersections showed the absolute percentage accuracy of vehicle counting, of no less than 92%. The error in determining the vehicle speed by the projection method, taking into account the camera calibration, did not exceed 1.5 km/h.
Biomechanical comparison of vertical suture techniques for repairing radial meniscus tear
Authors: Hang Guanqi , Yew Andy Khye Soon , Chou Siaw Meng , Wong Yoke Rung , Tay Shian Chao , Lie Denny Tijauw Tjoen 
Published: October 2020

Abstract
Purpose
The aim of this study was to (1) develop suture techniques in repairing radial meniscal tear; (2) to compare the biomechanical properties of the proposed repair techniques with the conventional double horizontal technique.

Methods
Thirty-six fresh-frozen porcine medial menisci were randomly assigned into four groups and a complete tear was made at the midline of each meniscus. The menisci were subsequently repaired using four different repair techniques: double vertical (DV), double vertical cross (DVX), hybrid composing one vertical and one horizontal stitch, and conventional double horizontal (DH) suture technique with suturing parallel to the tibia plateau. The conventional double horizontal group was the control. The repaired menisci were subjected to cyclic loading followed by the load to failure testing. Gap formation and strength were measured, stiffness was calculated, and mode of failure was recorded.

Results
Group differences in gap formation were not statistically significant at 100 cycles (p = .42), 300 cycles (p = .68), and 500 cycles (p = .70). A trend was found toward higher load to failure in DVX (276.8 N, p < .001), DV (241.5 N, p < .001), and Hybrid (237.6 N, p < .001) compared with DH (148.5 N). Stiffness was also higher in DVX (60.7 N/mm, p < .001), DV (55.3 N/mm, p < .01), and Hybrid (52.1 N/mm, p < .01), than DH group (30.5 N/mm). Tissue failure was the only failure mode observed in all specimens.

Conclusion
Our two proposed vertical suture techniques, as well as the double vertical technique, had superior biomechanical properties than the conventional technique as demonstrated by higher stiffness and higher strength.
Decolorization and detoxification of triphenylmethane dyes by isolated endophytic fungus, Bjerkandera adusta SWUSI4 under non-nutritive conditions
Authors: Gao Tiancong , Qin Dan , Zuo Shihao , Peng Yajun , Xu Jieru , Yu Baohong , Song Hongchuan , Dong Jinyan 
Published: October 2020

AbstractBiodecolorization by microorganisms is a potential treatment technique because they seem to be environmentally safe. In the present study, the decolorization and detoxification of cotton blue, crystal violet, malachite green and methyl violet by endophytic fungi were investigated. Preliminary screening result indicated that SWUSI4, identified as Bjerkandera adusta, demonstrated the best decolorization for the four TPM dyes within 14 days. Furthermore, optimization result demonstrated the decolorization rate could reach above 90% at 24 h by live cells of isolate SWUSI4 when 4 g biomass was added into 100-mL dyes solution with the concentration 50 mg/L and shaking (150 rpm) conditions. Moreover, decolorization mechanism analysis shows that the decolorization was caused by the isolate SWUSI4 that mainly includes both absorption of biomass and/or degradation of enzymes. Biosorption of dyes was attributed to binding to hydroxyl, amino, phosphoryl alkane, and ester–lipids groups based on Fourier transform infrared (FTIR) analyses. The biodegradation potential of SWUSI4 was further suggested by the change of peaks in the ultraviolet–visible (UV–vis) spectra and detection of manganese peroxidase and lignin peroxidase activities. Finally, the phytotoxicity test confirmed that the toxicity of TPM dyes after treatment with SWUSI4 was significantly lower than that before treatment. These results indicate that an endophytic SWUSI4 could be used as a potential TPM dyes adsorption and degradation agent, thus facilitating the study of the plant–endophyte symbiosis in the bioremediation processes.
A coupled core-mantle evolution: review and future prospects
Authors: Nakagawa Takashi 
Published: October 2020

AbstractIn this review, I provide the current status and future prospects for the coupled core-mantle evolution and specifically summarize the constraints arising from geomagnetism and paleomagnetism on the long-term secular variations of the geomagnetic field. The heat flow across the core-mantle boundary (CMB) is essential for determining the best-fit scenario that explains the observational data of geomagnetic secular variations (e.g., onset timing of the inner core growth, geomagnetic polarity reversals, and westward drift) and should include the various origins of the heterogeneous structures in the deep mantle that have affected the heat transfer across the core-mantle boundary for billions of years. The coupled core-mantle evolution model can potentially explain the onset timing of the inner core and its influence on the long-term geomagnetic secular variations, but it is still controversial among modeling approaches on the core energetics because the paleomagnetic data contains various uncertainties. Additionally, with the coupled core-mantle evolution model in geodynamo simulations, the frequency of the geomagnetic polarity reversals can be explained with the time variations of the heat flow across the CMB. Additionally, the effects of the stable region in the outermost outer core to the magnetic evolution are also crucial but there would be still uncertain for their feasibility.However, despite this progress in understanding the observational data for geomagnetic secular variations, there are several unresolved issues that should be addressed in future investigations: (1) initial conditions—starting with the solidification of the global magma ocean with the onset timing of plate tectonics and geodynamo actions and (2) planetary habitability—how the dynamics of the Earth’s deep interior affects the long-term surface environment change that has been maintained in the Earth’s multisphere coupled system.
Maritime supply chain sustainability: South-East Finland case study
Authors: Lähdeaho Oskari , Hilmola Olli-Pekka , Kajatkari Riitta 
Published: October 2020

AbstractEmphasis on sustainability practices is growing globally in the shipping industry due to regulations on emissions from transportation as well as increasing customer demand for sustainability. This research aims to shed light on the environmental sustainability of companies involved in maritime logistics at the major Finnish seaport, HaminaKotka. This seaport is a part of International Maritime Organization’s (IMO) Baltic and North Sea emission control area, with special emission-reducing measures contributing directly to United Nations’ Sustainable Development Goals (SDGs) by mitigating negative impacts of industrial activity on environment and climate change. Two semi-structured interviews with companies at HaminaKotka were carried out to construct a case study examining the sustainability challenges at hand. In addition, experience of one of the authors in a managerial position at the studied seaport complex, as well as the sustainability communications of the companies situated in the area were used to support the findings. The companies improve environmental sustainability by using multimodal transport chains, alternative fuels in the transports, and environmental sustainability demands towards their partners. However, the most important measures, according to these companies, are transport mode selection and cargo load optimization. Moreover, companies have identified bottlenecks of cargo flow at the hinterland due to road infrastructure constraints. As regulations and customers are requiring environmental sustainability, companies are forced to renew their operations, strategy and business models. Especially, the emission-reducing regulations drive companies to implement means to control the produced emissions.
Development of a straight vertebrate body axis
Authors: Bagnat Michel , Gray Ryan S. 
Published: October 2020

ABSTRACT
The vertebrate body plan is characterized by the presence of a segmented spine along its main axis. Here, we examine the current understanding of how the axial tissues that are formed during embryonic development give rise to the adult spine and summarize recent advances in the field, largely focused on recent studies in zebrafish, with comparisons to amniotes where appropriate. We discuss recent work illuminating the genetics and biological mechanisms mediating extension and straightening of the body axis during development, and highlight open questions. We specifically focus on the processes of notochord development and cerebrospinal fluid physiology, and how defects in those processes may lead to scoliosis.
Clergy-perpetrated sexual abuse of minors – case study
Authors: Więcek-Durańska Anna 
Published: October 2020

Cel pracyGłównym celem badań było pokazanie nie tyle skali samego zjawiska wykorzystywania seksualnego małoletnich przez osoby duchowne, co ukazanie sposobu działania sprawców i motywacji towarzyszącej popełnianiu czynów. Ponadto badanie miało również na celu ukazanie tła sytuacyjnego czynu, sposobu reakcji osób pokrzywdzonych oraz środowiska, w którym doszło do popełnienia przestępstwa.MetodaBadanie empiryczne obejmowało analizę jakościową i ilościową dokumentacji zebranej przez Fundację zajmującą się wsparciem, pomocą dla osób, które doznały molestowania seksualnego ze strony osób duchownych. Do badań przygotowany został kwestionariusz ankiety obejmujący dane dotyczące okoliczności zdarzenia, informacje dotyczące sprawcy, osoby pokrzywdzonej oraz konsekwencji (sankcji) prawnych i pozaprawnych. Zebrano informacje o 80 sprawach karnych z lat 2001-2019, w których doszło do prawomocnego skazania osoby duchownej.WynikiAnaliza materiału empirycznego pozwoliła na opracowanie modeli działania sprawców, sposobów wyboru osób pokrzywdzonych oraz podejmowanych aktywności w celu utrzymania w tajemnicy nadużyć wobec małoletnich. W ramach prowadzonych analiz opracowano również charakterystyki osób pokrzywdzonych, wyodrębniono cechy specyficzne dla różnych modeli postępowania duchownych.WnioskiWarto zwrócić uwagę na fakt, że w znacznym odsetku spraw nadużycia seksualne ze strony duchownych wobec osób małoletnich miały charakter bezpośredniej przemocy fizycznej jak i podejmowania regularnego współżycia seksualnego. Nie wszyscy sprawcy poddani zostali odpowiednim badaniom diagnostycznym w celu weryfikacji zaburzeń preferencji seksualnych pod postacią pedofilii. W badanej grupie spraw aż w co trzecim przypadku sprawca po ujawnieniu czynów przenoszony był do innej parafii, gdzie dochodziło do kolejnych podobnych czynów.
Competition for Context-Sensitive Consumers
Authors: Apffelstaedt Arno , Mechtenberg Lydia 
Published: October 2020

When preferences are sensitive to context, firms may influence purchase decisions by designing the environment of consumption choices. This paper studies how competitive retailers optimally design their product line if preferences at the store depend on whether the choice set draws consumer attention to the quality or price of a product. Before making a purchase decision, a consumer chooses among retailers without (fully) anticipating that her preferences at the store are malleable. We show that this setup can align evidence on retailer marketing practices and the existence of loss leaders with the experimental literature on decoy effects: in equilibrium, retailers use loss leaders to attract the consumer to the store and decoy products to draw consumer attention at the store to more profitable alternatives featuring a higher price (inducing a profitable upsell) or lower production cost (inducing a profitable downsell). We embed and compare the predictions of three recent specifications of choice-set dependent attention—namely, Salience, Focusing, and Relative Thinking. All three specifications predict that firms construct choice environments that utilize decoy effects to up- or downsell the consumer. Because they differ in how attention can be directed using the product line, however, they differ in their predictions of how the decoy will be positioned in the price-quality space. This paper was accepted by Yan Chen, decision analysis.
Poderes, trajetórias e administração no Império português (séculos XVI-XVIII)
Authors: Da Silva Rafael Ricarte , Carvalho Reinaldo Forte 
Published: October 2020

Apresentação. Revista Maracanan, Rio de Janeiro, PPGH-UERJ, n. 25 - "Poderes, trajetórias e administração no Império português (séculos XVI-XVIII)", set.-dez. 2020.