bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atraumatic forceps-guided insertion of the cervical pessary: a new technique to prevent preterm birth in women with asymptomatic cervical shortening
Authors: Dereli Murat Levent , Obut Mehmet , Özkan Sadullah , Sucu Sadun , Fıratlıgil Fahri Burçin , Kurt Dilara , Kurt Ahmet , Sarsmaz Kemal , Tolunay Harun Egemen , Çağlar Ali Turhan , Üstün Yaprak Engin 
Published: December 2024

Abstract

Objectives
As previous studies on the use of a cervical pessary to prevent preterm birth (PTB) have produced conflicting results, we aimed to investigate the feasibility, acceptability and safety of a new technique for inserting a cervical pessary and compare it with the traditional technique in patients at high risk of PTB.

Methods
Women at high risk of PTB treated with a cervical pessary between January 2018 and January 2021 were retrospectively evaluated. After applying exclusion criteria, a total of 68 eligible patients were identified and retrospectively analyzed. The primary outcome was spontaneous PTB before 34 weeks’ gestation (WG).

Results
Of 68 participants, 39 were treated with the traditional method (group 1) and 29 with the new insertion technique (group 2). The rate of spontaneous PTB before 34 WG was significantly lower in group 2 (p=0.020). Birthweight, APGAR scores and satisfaction with the method were significantly higher, while PTB before 37 WG was significantly lower in group 2 (p=0.043, 0.010, 0.009, 0.042 and 0.014, respectively). There were no significant differences in the rates of perinatal death (12.8 vs. 3.4 % in groups 1 and 2, respectively; p=0.229). The concomitant use of vaginal progesterone was required more frequently in group 1. According to the binary regression analysis, the new insertion technique resulted in a 5.42 and 3.97-fold protection against PTB before 34 and 37 WG.

Conclusions
Our preliminary results show that our new technique of pessary insertion is more effective than the traditional method in preventing PTB due to cervical shortening.
Investigation of weak solutions for p(z)-Kirchhoff equations by Young measure techniques
Authors: Allalou Mouad , Raji Abderrahmane 
Published: December 2024

Abstract
The present article deals with the existence of weak solutions to a class of

p

(

z

)

p\left(z)

-Kirchhoff-type problems. To address these problems, we employ a variational approach in conjunction with the theory of variable exponent Sobolev spaces, while imposing suitable assumptions on the source term. Furthermore, we utilize the theory of Young measures.
Enhanced mechanical properties of Sr-modified Al–Mg–Si alloy by thermo-mechanical treatment
Authors: Karakoca Alper , Yılmaz Serdar Osman 
Published: December 2024

Abstract
In this study, the effect of thermomechanical treatments applied to strontium-modified A360 alloy on the microstructure and mechanical properties of the alloy was investigated. Optical microscopy, XRD, and SEM were employed to examine the microstructural properties, while tensile and hardness tests were conducted on the samples to evaluate the mechanical properties. It was observed that the strength values increased as the deformation amount increased, and subsequently, optimum conditions (tensile strength and ductility) were determined after the subsequent aging treatment. Following cold deformation, dendritic structure shifted towards the direction of deformation along with the eutectic silicon structure. After aging, it was found that the dendritic structure transformed into equiaxed grains at certain temperature. The highest tensile strength of 383 MPa was achieved in the sample with a deformation amount of 70 %. In this case, the ductility value was 2.85 %. Subsequently, the optimum conditions after aging were determined as 160 °C & 4 h, resulting in a tensile strength of 341 MPa and ductility of 3.62 %.
Analysis of farm performance to realize the sustainability of organic cabbage vegetable farming in Getasan Semarang, Indonesia
Authors: Winahyu Wulansari , Rahayu Endang Siti , Darwanto Dwidjono Hadi , Harisudin Mohamad 
Published: December 2024

Abstract
Increasing farmers’ income is possible through high-value markets. Employment, access to financing, and technical support have favorable effects and a rise in income. This research seeks to establish the sustainability of organic cabbage farming through economic performance analysis. Quantitative research methods were conducted in this research. Descriptive quantitative analysis was performed with PLS-SEM software. The research data comprise primary data and secondary data. Of the 11 pathway coefficients in this study, only 9 were significant. The protection variable was positively related to the production optimization construct but did not significantly affect financial performance. The variable “healthy and safe” was positively associated with significant constructs of “financial performance” and “production optimization.” The variable “capacity development” was positively related to the constructs of “financial performance” and “production optimization.” The “technical” variable was significantly positively associated with the construct of “financial performance” but did not significantly affect the construct of “optimization of production.” The variable “production optimization” is positively related to the construct of “financial performance” and the construct of “farm performance” of farmers. Agricultural extension and training must be carried out to improve farmers’ technical knowledge. Government subsidies to support organic farming are also needed to ensure the sustainability of organic cabbage farming in the Semarang district.
Características epidemiológicas de la tuberculosis en Colombia
Authors: Cruz-Martínez Oscar Andrés , Trujillo-Trujillo Julian 
Published: December 2024

Introducción. La tuberculosis (TB) representa un grave problema de salud pública mundial, regional y nacional, toda vez que los datos epidemiológicos indican aún una alta carga de morbimortalidad con graves impactos sociales, económicos y en salud.
Objetivo. Describir las características epidemiológicas de la TB en Colombia.
Materiales y métodos. Estudio descriptivo realizado con los datos oficiales del Programa Nacional de Control de la Tuberculosis de Colombia. Se realizó una caracterización de los casos de TB reportados en el país entre 2019 y 2022. Respecto a los resultados del tratamiento, dada la duración del mismo, para TB sensible se analizaron de 2017 a 2021 y para TB farmacorresistente, de 2017 a 2020. Las tasas de incidencia y mortalidad por TB se calcularon usando los datos históricos registrados en el Programa Nacional de Control de la Tuberculosis entre 2002 y 2022.
Resultados. Entre 2002 y 2015 se observó una tendencia estable en la tasa de incidencia de TB (23-26.4 casos por cada 100 000 habitantes); entre 2016 y 2019 esta tasa sufrió un ligero aumento (25.0 a 27.3 casos), pero en 2020 y 2021, dada la reducción en la detección de casos producto de la pandemia por COVID-19, disminuyó (22.0 y 25.9 casos), aunque en 2022 se observó un aumento importante (31.6 casos por cada 100 000 habitantes), año en el que la tasa de mortalidad fue de 2.4 casos por cada 100 000 habitantes. La proporción de casos en menores de 15 años aumentó entre 2019 y 2022 (2.71% vs. 3.30%). Entre 2017 y 2021 el tratamiento exitoso de casos nuevos y recaídas osciló entre 60.97% y 75.0%.
Conclusiones. El comportamiento de la incidencia y la mortalidad por TB en Colombia muestra una tendencia al aumento.
Prismatic bottles from the auxiliary fort and vicus of Intercisa
Authors: Dévai Kata 
Published: December 2024

AbstractThis paper presents the glass prismatic bottles and fragments brought to light in the Roman settlement of Intercisa (today Dunaújváros, Hungary). Bottles occur in a low number among the finds of the vicus and the castellum of Intercisa. Bottles and containers account for around 15% of all vessel fragments, while prismatic bottles have a lower share, around 4%. Almost all identifiable fragments are square bottles, with a single rectangular one amongst them. Their designs vary; most feature geometric motifs, while plant motifs and inscriptions are less frequent. Most fragments presented below are yet unpublished.
Brain-derived neurotrophic factor in the pathogenesis of comorbid coronary artery disease and depression: a review
Authors: Kytikova O. Yu. , Antonyuk M. V. , Novgorodtseva T. P. , Gvozdenko T. A. 
Published: December 2024

Coronary artery disease (CAD) and depression are characterized by high bilateral comorbidity, but its pathogenesis is practically not studied.In the last decade, neurogenic mechanisms of the inflammatory response and brain-derived neurotrophic factor (BDNF), which can explain the relationship between depression and CAD, have been studied. The review summarizes the available information on BDNF role in the pathogenesis of CAD and depression, as well as their comorbid course for the period of 2019-2024. Based on the literature review, we identified the components and systems that are most promising for studying the BDNF role in the pathogenesis of these multifactorial diseases (genetics, inflammation, neuroinflammation, endothelial dysfunction and platelet hyperactivation, hypothalamic-pituitary-adrenal system, low-density lipoproteins and triglycerides). The review emphasizes the important role of BDNF in the development of depression in CAD and the need for further research in this area.
Ghost segments in Sengwer nouns
Authors: Falletti Federico , Remijsen Bert 
Published: December 2024

Like other Kalenjin languages, Sengwer has a complex and understudied noun morphology which makes use of an abundance of affixes as well as word-internal tone and ATR changes. In addition, its nominal inflectional paradigms are teeming with unexpected stem-final segments which appear in certain morphological conditions but are absent in others. The phonological composition of this stem-final latent material is not predictable and varies from noun to noun—C, V, CV and even CCV are all possible.This paper provides a first description of the form and distribution of these segments as well as a novel analysis of their behaviour which explains much of the variation and irregularity seen in nominal inflection. In particular, this paper presents evidence that, although some of these latent segments are part of the root, others are part of suffixes and others still are morphologically active suffixes in their own right. In a departure from earlier studies, we argue that these segments should not be analysed as being inserted thematic material and are better understood as deleted ghost segments instead. Though the term ghost refers to a common phenomenon cross-linguistically, it has been characterised using different labels (e.g., latent, liaison, floating) depending on the tradition and the element affected. Building on Zimmermann’s (2019) definition of ghosts, we argue that these phenomena do not only occur to satisfy synchronic phonological constraints but can also be the result of historical processes no longer at work.
Selection of the composition of the initial charge during the rolling melting of the mineral melt
Authors: Matyukhin V. I. , Matyukhina A. V. , Bolotov A. V. 
Published: December 2024

To obtain a melt of the required composition, the chemical composition of the available raw materials is pre-determined experimentally or according to reference books. Using data from derivatographic studies and calculated melt compositions at the required acidity modulus, patterns of changes in melting temperatures and crystallization of charge materials, viscosity of the resulting melt and its fusibility are established. The selection of the charge composition ends with the compilation of the material and thermal balances of the melting unit. Ill. 1. Ref. 9.
Production of large-format corundum refractories of increased density using vibration molding and co-sintering technology
Authors: Poskotinova A. M. , Krasnyi B. L. , Ikonnikov K. I. , Galganova A. L. , Vershinin D. I. , Rodimov O. I. , Bernt D. D. , Sizova A. S. 
Published: December 2024

Using vibration molding and co-sintering technology, it was possible to obtain a corundum refractory material with a dense structure, the values of open porosity and average density of which are comparable with the values characteristic of fused-cast refractories. To obtain a filler for concrete mass, a comparative analysis of aluminous raw materials, deflocculating additives and methods of molding filler for large-format corundum refractories of increased density was carried out. Optimal parameters of the filler production technology were determined. Ill. 8. Ref. 15. Tab. 4.
Where Can I Sign My Language?: A Systematic Literature Review (2000–2019) of Young People's Access to Sign Language Socialisation Spaces in the Nordic Countries
Authors: Haualand Hilde , Hjulstad Johan , Ingjerd Legreid Ødemark  , Kermit Patrick 
Published: December 2024

This article presents the results from a systematic literature review of Nordic research studies from 2000 to 2019, addressing the question of children and adolescents' access to spaces where they can sign with peers and adults. The study is based on a dialogistic approach to language, and holds that languaging is inextricably tied to places and situations—that is, spaces and contexts in which people participate in interactions with others. Thus, acquiring sign language is not only about the child or adolescent's individual learning of sign language in an educational setting, but also about participation in sign language activities. The review addresses the paradoxical situation in the field of sign language education whereby formal recognition of sign language and the institutionalisation of rights to sign language education gained momentum at around the same time as the number of deaf schools began to decline. The results from the review indicate that very few studies of sign language pay attention to spaces where children and adolescents can interact with other people through sign language. It appears that current legislation, as well as research, emphasises the individual right to learn sign language for deaf and hard-of-hearing children, and has overlooked the significance of facilitating and protecting sign language-based socialisation spaces as significant sites for sign language learning, participation and acquisition.
Personalized approach to the biologicals’ selection in patients with severe asthma: real practice tools and new possibilities
Authors: Pavlova K. S. , Timoshenko D. O. , Osokin A. A. , Kofiadi I. A. , Kurbacheva O. M. 
Published: December 2024

Currently, the most effective approach to treating patients with severe uncontrolled asthma is the use of biologicals. These treatments are highly effective and safe, but not universal. Different biologicals block various parts of asthma pathogenesis. Also, biologicals have different effectiveness in relation to comorbidities. In this regard, the targeted therapy selection should be personalized, endotypeand phenotype-oriented.The aim of this review was to analyze the literature data on methods for personalized biologicals’ selection in patients with severe asthma that are currently used in clinical practice, as well as new prospects in this area.Conclusion. Laboratory and instrumental examination methods currently used for endoand phenotyping of severe asthma help in identifying the key pathogenetic factor in the disease development that serves as a basis for selection of the biological. However, biomarkers identified during routine examination are not absolute and are prone to exceptions. Also, the targeted therapy selection is based on a subjective determination of the prevailing pathogenetic mechanism when a patient with severe asthma has a mixed disease phenotype and meets the criteria for prescribing all available biologicals. Therefore, the search for biomarkers that predict the effect of a particular biological remains a relevant direction for future studies. The combined use of clinical, molecular-genetic examination results and evaluation of epigenetic markers can help in solving this problem. This review provides current data on the biologicals used in severe asthma treatment, the phenotyping and endotyping tools used in real practice, and also describes promising areas of the epigenetic biomarkers research.
Analysis of the incidence, disability and mortality rates of the Russian population due to respiratory diseases and COVID-19 in the period 2016 – 2021
Authors: Bystritskaya E. V. , Bilichenko T. N. , Misharin V. M. 
Published: December 2024

High incidence of respiratory diseases (RD) makes monitoring of the associated morbidity and mortality in the Russian population important for the public health.The aim was to study the incidence, disability and mortality rates associated with RD in 2016 – 2021 by federal districts of Russian Federation.Methods. Statistical data from the Ministry of Healthcare of the Russian Federation and Federal State Statistics Service was used.Results. There was an increase in the RD morbidity by 12.0% from 2019 to 2021 (from 40,694.7 to 45,560.7 per 100 thousand population, p < 0.001), and a 3-fold increase in the incidence of pneumonia. The RD incidence increased in all federal districts, with the maximum in the Northwestern Federal District (2021 – 55,680.9 per 100 thousand population). An increase in the RD-associated mortality rates (MR) by 95.8% was recorded from 2019 to 2021: from 40.3 to 78.7 deaths per 100,000 population. In 2021, the proportion of pneumonia in the structure of MR was 65.3%, and the hospital mortality due to RD increased. The proportion of people with primary disability due to RD decreased in 2021. The COVID-19 (COronaVIrus Disease 2019) incidence rate has been registered since 2020 (2020 – 3,391.1, 2021 – 8,085.7 cases per 100 thousand population). The MR associated with COVID-19 reached 98.8 per 100,000 population in 2020 and 319.1 per 100,000 population in 2021.Conclusion. In the period 2019 – 2021, there were an increase in the RD incidence in the Russian population, mostly due to pneumonia. The RD incidence and pneumonia incidence reached the maximum in 2021, which required expansion of the healthcare capacities at short notice.
Registry as a tool for monitoring effectiveness of immunobiological therapy for severe asthma in real clinical practice
Authors: Naumova V. V. , Kiseleva D. V. , Zykov K. A. , Beltyukov Е. К. , Klyachina E. S. , Nikiforova I. O. , Suvorkov P. A. 
Published: December 2024

Registry is a unique and universal mechanism for group and individual approaches to managing patients, including those with severe asthma (SA) who require targeted therapy.The aim is to evaluate the clinical and organizational potential of the SA patient registry as a tool for group and individual approaches to patient management, as a way to describe and systematize the signs of bronchial asthma, comorbid diseases, and monitoring immunobiological therapy (using anti-IgE therapy as an example) in patients with SA in Sverdlovsk region.Methods. The subject of the study was the Territorial Registry of Patients with SA of the Sverdlovsk region. The registry effectiveness was assessed based on the clinical and organizational indicators, including monitoring the effectiveness of 3-year anti-IgE therapy in patients with SA with an allergic component.Results. From 2016 to 2023, both inclusive, 198 patients with SA were entered into the registry. Analysis of the registry data allowed us to develop a scheme for SA phenotyping and selecting the 1st and 2nd line targeted drugs and a scheme for phenotyping and selecting a targeted drug for T2 inflammatory nasal diseases. Over 3 years of anti-IgE therapy with omalizumab, the ACT test increased from 9.00 to 19.50 points, the proportion of patients with partial and good asthma control increased by 13.89 times, the frequency of exacerbations decreased by 71.43%, FEV1 increased by 17.91%, and the proportion of patients requiring systemic corticosteroids decreased by 83.32%.Conclusion. The registry of SA patients has high clinical and organizational potential to describe and systematize the signs of bronchial asthma, comorbid diseases, and monitor the effectiveness and safety of immunobiological therapy. The 3-year anti-IgE therapy demonstrates statistically significant effectiveness in patients with SA with an allergic component.
Intracranial lesions: Histopathological and radiological correlation
Authors: Chag Shyama Manojkumar , Chaudhari Suraj Karshanbhai , Chaudhari Sanjay Namdev 
Published: December 2024

Intracranial space-occupying lesions (ICSOLs) include neoplastic and non-neoplastic lesions of the central nervous system. “In India, central nervous system neoplasms account for approximately 1.9% of all malignant tumours.” Biopsy and histopathology are essential for accurate diagnosis and preventing incorrect therapeutic interventions.The study aims to correlate histopathological and radiological diagnosis of intracranial lesions. Epidemiological parameters of various neoplastic and non-neoplastic intracranial lesions according to age, sex and site are assessed.The retrospective and prospective descriptive study, conducted at the tertiary care centre, analysed 104 cases of ICSOLs. The study utilised preoperative radiological reports, MRI (Primarily) or CT scan. The statistical analysis was performed using STATA (14.2). Frequencies and the chi-square test were used for calculation.In the present study, neoplastic lesions (93.27%) were more common than non-neoplastic lesions (6.73%), with a male predominance (Male: Female = 1.36:1). Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of radiological diagnosis in neoplastic lesions were 98.97%, 28.57%, 95.04%, 66.67% and 94.23% respectively, compared to histopathological diagnosis. P-value &#60;0.05 suggests statistically significant results.The study found a higher incidence of neoplastic intracranial lesions, likely due to the institute's fully functional oncology department. Radiological techniques offer non-invasive insights into lesion characteristics, while histopathological examination provides a definitive cellular-level diagnosis. Together, these methods enhance diagnostic accuracy, guide treatment decisions, and improve patient outcomes.
Non-tumor associated Psammoma bodies in cervical lymph node: A case report
Authors: James Nikita , Thomas Meeta , Pothen Lillykutty , Thomas Sonia Mary , Mathews Rebecca 
Published: December 2024

Psammoma Bodies (PBs), associated with thyroid carcinomas, raise diagnostic challenges when found without concurrent papillary thyroid carcinoma (PTC). This report presents a case of PBs in cervical lymph nodes without evidence of thyroid malignancy.A 53-year-old woman with neck swelling underwent total thyroidectomy. Despite PBs in cervical lymph nodes, microscopic examination revealed thyroid follicular nodular disease with no evidence of PTC.This case questions the diagnostic reliability of PBs without PTC. The study by Hunt et al. emphasized the potential for PTC detection in cases initially labeled as PBs-only, stressing the need for comprehensive evaluation.Differential diagnoses and the need for clinical correlation highlight the complexity of interpreting PBs without PTC. Seeking a second opinion and additional diagnostic tools may be crucial.PBs, despite their strong link to PTC, may not conclusively indicate malignancy when found alone. Management decisions should consider clinical context, patient history, and available diagnostic tools. Further exploration of PBs in benign thyroid conditions is encouraged for improved understanding and diagnostic accuracy in larger series. Collaborative efforts between pathologists and clinicians are essential for optimal patient care in such challenging cases.