bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGALAMAN ADAPTASI REMAJA PASCA BENCANA GEMPA DI LOMBOK NUSA TENGGARA BARAT
Authors: Anika Nova , Yusuf Ah , Tristiana Rr Dian 
Published: June 2020

Pendahuluan: Kejadian bencana dapat menimbulkan kerugian baik dari aspek fisik, psikologis, properti dan lingkungan. Bencana mempengaruhi kesejahteraan psikologis dan kesehatan mental individu, baik orang dewasa maupun anak-anak dan remaja. Diperlukan proses adaptasi pasca bencana untuk mencapai respon yang adaptif bagi remaja sehingga stress pasca trauma tidak menjadi patologis. Tujuan dari penelitian ini adalah untuk mengeksplorasi pengalaman adaptasi remaja pasca bencana gempa di Lombok Nusa Tenggara Barat tahun 2018.Metode: penelitian ini menggunakan metode penelitian kualitatif fenomenologi dengan teknik wawancara mendalam kepada 18 orang remaja terdampak bencana gempa di Lombok Nusa Tenggara Barat, Analisis data yang digunakan mengacu pada sembilan langkah teknik analisis data collaizi.Hasil: hasil dari penelitian ini diperoleh 11 tema: 1) Perubahan cara bersosialisasi, 2) Perubahan peran, 3) Menggali kemampuan lain 4) Respon terhadap gempa, 5) Upaya mengatasi dampak bencana, 6) Sumber Dukungan, 7) Jenis Dukungan, 8) Makna kejadian bencana, 9) Harapan untuk Lombok, 10) Harapan pada diri sendiri, 11) Harapan pada pihak berwenang.Kesimpulan: Upaya menghadapi dampak gempa atau Strategi koping yang digunakan remaja berupa perubahan spiritual dan distraksi. Mendekatkan diri kepada tuhan dengan melakukan berbagai bentuk ibadah sesuai dengan agama yang di anut memiliki peranan penting untuk dapat beradaptasi dengan dampak yang ditimbulkan oleh bencana gempa pada remaja. ABSTRACTIntroduction: Disaster events can cause harm from physical, psychological, property and environmental aspects. Disasters affect the psychological well-being and mental health of individuals, both adults and children and adolescents. Post-disaster adaptation process is needed to achieve an adaptive response for adolescents so that post-traumatic stress does not become pathological. The purpose of this study was to explore the experiences of adolescent adaptation after the earthquake disaster in Lombok West Nusa Tenggara in 2018.Method: This study used phenomenological qualitative research methods with in-depth interviews with 18 adolescents affected by the earthquake disaster, Analysis of data used refers to nine steps colaizzi data analysis techniques.Results: the results of this study obtained 11 themes: 1) changes in how to socialize, 2) changes in roles, 3) Exploring other abilities 4) Response to earthquakes, 5) Efforts to overcome the impact of disasters, 6) Sources of Support, 7) Types of Support, 8) Meanings of disasters, 9) Expectations for Lombok, 10) Expectations for oneself, 11) Expectations for authorities.Conclusion: Efforts to deal with the effects of earthquakes or coping strategies used by adolescents in the form of spiritual changes and distractions. Get closer to God by doing various forms of worship in accordance with the religion that is followed has an important role to be able to adapt to the impact caused by the earthquake disaster in adolescents.
HUBUNGAN BEBAN PENGASUHAN DENGAN POLA INTERAKSI KELUARGA ORANG DENGAN GANGGUAN JIWA (ODGJ) DI RUMAH
Authors: Nababan Yosevin Karunia , Yusuf Ah , Nimah Lailatun 
Published: June 2020

Pendahuluan: Keluarga sebagai caregiver penderita ODGJ mengalami beban berupa gangguan fisik, emosional dan finansial karena perilaku abnormal pasien, disfungsi sosial serta ketidakmampuan untuk menghidupi dirinya sendiri. Akibat beban yang mereka alami, caregiver ODGJ menunjukkan gejala stress dan kecemasan yang tinggi hingga mempengaruhi pola interaksi. Metode: Rancangan penelitian ini adalah cross sectional . Sampel sejumlah 123 caregiver keluarga penderita ODGJ yang berkunjung di Poliklinik kesehatan jiwa RSJ Menur Surabaya dan didapatkan dengan menggunakan teknik konsekuetive sampling. Data diperoleh dari kuesioner Zarit Caregiver Burden Questionaire dan kuesioner pola interaksi kemudian dianalisis dengan uji statistik korelasi Spearman Rho. Hasil: Hasil penelitian menunjukkan bahwa ada hubungan yang signifikan antara beban pengasuhan dengan pola interaksi (p=0,032) pada nilai signifikansi < 0,05. Koefisien korelasi r=-0,194. Hal ini menunjukkan bahwa terdapat hubungan yang rendah dengan arah negatif, sehingga semakin tinggi beban pengasuhan yang dirasakan semakin rendah pola interaksi yang dialami oleh caregiver keluarga penderita ODGJ. Kesimpulan : Terdapat hubungan yang rendah dan bermakna antara beban pengasuhan dengan pola interaksi caregiver keluarga penderita ODGJ dengan arah negatif, yang berarti semakin tinggi beban pengasuhan yang dirasakan oleh caregiver, maka pola interaksinya semakin rendah. ABSTRACTIntroduction: Families as caregivers their family with mental disorder experience the burden of physical, emotional and financial disturbances due to the patient's abnormal behavior, social dysfunction and inability to support themselves. Due to the burden they experience, caregivers show symptoms of high stress and anxiety to affect patterns of interaction.Method: The design of this study was cross sectional. A sample of 123 family sufferers of mental disorder member who visited the mental health polyclinic at the Menur General Hospital in Surabaya was obtained using a consistent sampling technique. Data were obtained from the Zarit Caregiver Burden Questionaire and the interaction pattern questionnaire was then analyzed using the Spearman Rho correlation test.Results: The results showed that there was a significant relationship between the burden of caregiving with interaction patterns (p = 0.032) at a significance value <0.05. The correlation coefficient r = -0,194. This shows that there is a low relationship with a negative direction, so that the higher the burden of caregiving is felt the lower the interaction patterns experienced by family caregivers of people with mental disorder.Conclusion: There is a significant relationship between caregiving burden with the negative caregiver interaction patterns of mental disorder sufferers' families, which means that the higher the caregiver burden felt by caregivers, the lower the interaction patterns.
the Forecast of Weekly β-HCG and Progesterone for Early Pregnancy
Authors: Yang Yan , Duan Jie , Wang Yan , Du Xin , wu Wei , Huang Yan ming 
Published: June 2020

Abstract
Background: Serum beta human chorionic gonadotropin (β-HCG) and progesterone levels are both monitored to assess the status of early pregnancy. Deviations from the expected levels of these hormones may indicate abnormal pregnancy. However; the relationship between progesterone levels and the magnitude of weekly β-HCG increases, as well as their combined predictive value for pregnancy outcome, is still debated. This study evaluated the predictive value of weekly serum β-HCG multiplication and progesterone levels on early pregnancy outcomes. Methods: This retrospective study reviewed patients with pregnancy confirmed by β-HCG in our hospital. Weekly β-HCG and progesterone levels were analyzed and ultrasonography was performed as necessary to determine outcomes at 13 weeks gestation. Results: There were 277 viable intrauterine pregnancies, 102 spontaneous abortions, and 59 ectopic pregnancies. At weeks 5-8, β-HCG was multiplied by 6.76, 6.21, 2.11, and 0.68 respectively. Logit models were established with the logarithm of HCG (LHCG) and progesterone as independent variables to predict viable intrauterine pregnancy. The sensitivity, specificity, and overall accuracy for the models were 85.9% and 90.25%, 44.72% and 72.04%, and 70.77% and 83.6%, respectively. When progesterone was ≥10 ng/ml, the sensitivity and specificity for predicting viable pregnancy were 90.25% and 72.04%, respectively. When progesterone was <10 ng/ml, the sensitivity and specificity for predicting ectopic pregnancy and complete abortion were 94.2% and 81.57%78.86%, respectively. Progesterone values were significantly different for viable pregnancy, abortion, and ectopic pregnancy (p<0.0001). A joint progesterone and LHCG model to predict viable pregnancy had 88.8% sensitivity, 75.2% specificity, and 83.8% overall prediction accuracy.Conclusion: Weekly β-HCG multiplication and progesterone levels can predict early pregnancy outcomes individually or jointly.
Genomic analysis of Escherichia coli strains isolated from diseased chicken in the Czech Republic
Authors: Papoušková Aneta , Masaříková Martina , Valček Adam , Šenk David , Čejková Darina , Jahodářová Eva , Čížek Alois 
Published: June 2020

Abstract
Background: Avian pathogenic Escherichia coli (APEC) can cause various extraintestinal infections in poultry, resulting in massive economic losses in poultry industry. In addition, some avian E. coli strains may have zoonotic potential, making poultry a possible source of infection for humans. Due to its extreme genetic diversity, this pathotype remains poorly defined. This study aimed to investigate the diversity of colibacillosis-associated E. coli isolates from Central European countries with a focus on the Czech Republic. Results: Of 95 clinical isolates subjected to preliminary characterization, 32 were selected for whole-genome sequencing. A multi resistant phenotype was detected in a majority of the sequenced strains with the predominant resistance to β-lactams and quinolones being associated with TEM-type beta-lactamase genes and chromosomal gyrA mutations respectively. The phylogenetic analysis confirmed a great diversity of isolates, that were derived from nearly all phylogenetic groups, with predominace of B2, B1 and C phylogroups. Clusters of closely related isolates within ST23 (phylogroup C) and ST429 (phylogroup B2) indicated a possible local spread of these clones. Besides, the ST429 cluster carried blaCMY-2, -59 genes for AmpC beta-lactamase and isolates of both clusters were generally well-equipped with virulence-associated genes, with considerable differences in distribution of certain virulence-associated genes between phylogenetically distant lineages. Other important and potentially zoonotic APEC STs were detected, incl. ST117, ST354 and ST95, showing several molecular features typical for human ExPEC. Conclusions: The results support the concept of local spread of virulent APEC clones, as well as of zoonotic potential of specific poultry-associated lineages, and highlight the need to investigate the possible source of these pathogenic strains.
Comparison of the effects of empagliflozin and glimepiride on endothelial function in patients with type 2 diabetes: A randomized controlled study
Authors: Tamura Haruka , Kondo Yoshinobu , Ito Kohei , Hasebe Masanori , Satoh Shinobu , Terauchi Yasuo 
Published: June 2020

Abstract
Background: Among patients with type 2 diabetes and established cardiovascular disease, those receiving empagliflozin have a lower rate of primary composite cardiovascular outcomes and death from any cause. While treatment with sulfonylurea reduces microvascular complications in diabetes, it increases cardiovascular hospitalization or mortality when combined with metformin. In the present study, we assessed the effects of empagliflozin and glimepiride, a commonly prescribed sulfonylurea, on endothelial function using flow-mediated dilation (FMD) to estimate arteriosclerosis and cardiovascular events in patients with type 2 diabetes.Methods: In this prospective, open-label, randomized, parallel-group study, 58 patients with type 2 diabetes received metformin and glargine before bedtime for 12 weeks. This was followed by additional treatment with either 10 mg empagliflozin or 0.5 mg glimepiride for 12 weeks. The primary outcome was the change in the FMD measurement (DFMDs), measured prior to and after 12 weeks of additional treatment. Secondary outcomes comprised changes in metabolic markers and body composition.Results: An analysis of the empagliflozin group (n = 30) and glimepiride group (n = 28) showed no significant differences in DFMDs (empagliflozin, −0.19 ± 2.34%; glimepiride, −0.37 ± 2.77%; P = 0.79). Similarly, changes in glycated hemoglobin were similar between the two groups. However, a significant difference in body weight changes was observed between the two groups (empagliflozin, −0.59 ± 2.5 kg; glimepiride, 1.2 ± 3.0 kg; P = 0.02). In addition, an analysis of the body composition revealed that body fluid volume significantly decreased after empagliflozin treatment (baseline, 35.8 ± 6.8 L; after 12 weeks, −0.33 ± 0.72 L; P = 0.03).Conclusions: Empagliflozin did not improve endothelial function when compared to that with glimepiride for patients with type 2 diabetes but decreased body fluid volumes. This suggested that the coronary-protective effect of empagliflozin is not derived from protection of the endothelial function but rather from a reduction in the risk of heart failure.Trial Registration: This trial was registered on September 13, 2016; UMIN000024001.
Etiology and prognosis of canalicular laceration repair using canalicular anastomosis combined with bicanalicular stent intubation
Authors: Guo Tao , Qin Xiuhong , Wang Hongwei , Lu Yang , Xu Li , Ji Jiali , Xiao Caiwen , Zhang Zhenzhen 
Published: June 2020

Abstract
Background: To evaluate the etiology of lacrimal canalicular laceration and explore the possible risk factors influencing prognosis. Methods: The data of 142 patients (142 eyes) with lacrimal canalicular lacerations who were surgically treated using canalicular anastomosis combined with bicanalicular stent intubation between March 2017 and March 2018 were reviewed. The analyzed data contained demographic information, types of trauma, injury locations, associated additional ocular injuries, and surgical outcomes at follow-up. The main outcome measures were anatomic success rate, functional success rate, and complications of surgery.Results: The mean patient age was 42.07 years (ranging from 1–75 years). Among the 142 patients, 112 (78.87%) were males. Upper and lower canalicular lacerations were found in 14 (9.86%) and 112 (78.87%) patients, respectively. Meanwhile, both upper and lower canalicular lacerations were found in 16 (11.27%) patients. Electric bike accidents comprised the leading cause of injury, accounting for 76 (53.52%) cases. There were 100 (70.42%) patients who had lid lacerations without tarsal plate fracture and 42 (29.58%) patients who had lid lacerations with tarsal plate fractures. The anatomic success rate was 98.59% and the functional success rate was 83.8%. The functional reconstruction failure rates were higher in patients with indirect injuries, lid lacerations with tarsal plate fractures, and those with punctum splitting (P<0.05). Surgical complications were detected in the form of lacrimal punctum ectropion in 3 (2.11%) patients, punctum splitting in 2 (1.41%) patients, and stent extrusion and loss in 2 (1.41%) patients. Conclusions: Electric bike accidents have become the leading cause of injury instead of motor vehicle accidents because of the changes in the lifestyles of people. Indirect injuries, lid lacerations with tarsal plate fractures, and those with punctum splitting were significantly more likely to lead to poor prognosis, as confirmed by the lower functional success rate of surgery.
Magnitude of Problematic Anger and its Predictors in the Millennium Cohort
Authors: Adler Amy , LeardMann Cynthia A. , Roenfeldt Kimberly , Jacobson Isabel , Forbes David 
Published: June 2020

Abstract
Background: Problematic anger is intense anger associated with elevated generalized distress and that interferes with functioning. It also confers a heightened risk for the development of mental health problems. In military personnel and veterans, previous studies examining problematic anger have been constrained by sample size, cross-sectional data, and measurement limitations. Methods: The current study used Millennium Cohort survey data (N = 90,266) from two time points (2013 and 2016 surveys) to assess the association of baseline demographics, military factors, mental health, positive perspective, and self-mastery, with subsequent problematic anger. Results: Overall, 17.3% of respondents reported problematic anger. In the fully adjusted logistic regression model, greater risk of problematic anger was predicted by certain demographic characteristics as well as childhood trauma and financial problems. Service members who were in the Army or Marines, active duty (vs. reserves/national guard), and previously deployed with high levels of combat had increased risk for problematic anger. Veterans were also more likely to report problematic anger than currently serving personnel. Mental health predictors included posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and comorbid PTSD/MDD. Higher levels of positive perspective and self-mastery were associated with decreased risk of problematic anger. Conclusion: Not only did 1 in 6 respondents report problematic anger, but risk factors were significant even after adjusting for PTSD and MDD, suggesting that problematic anger is more than an expression of these mental health problems. Results identify potential points of early intervention and clinical treatment for addressing problematic anger in the military and veteran context.
An exploration of the complex biogeographical history of the Neotropical banner-wing damselflies (Odonata: Polythoridae)
Authors: Herrera Melissa Sanchez , Beatty Christopher , Nunes Renato , Salazar Camilo , Ware Jessica L 
Published: June 2020

Abstract
Background: The New World Tropics has experienced a dynamic landscape across evolutionary history and harbors a high diversity of flora and fauna. While there are some studies addressing diversification in Neotropical vertebrates and plants, there is still a lack of knowledge in arthropods. Here we examine temporal and spatial diversification patterns in the damselfly family Polythoridae, which comprises seven genera with a total of 58 species distributed across much of Central and South America. Results Our time-calibrated phylogeny for 48 species suggests that this family radiated during the late Eocene (~33 Ma), diversifying during the Miocene. As with other neotropical groups, the Most Recent Common Ancestor (MRCA) of most of the Polythoridae genera has a primary origin in the Northern Andes though the MRCA of at least one genus may have appeared in the Amazon Basin. Our molecular clock suggests correlations with some major geographical events, and our biogeographical modeling (with BioGeoBEARS and RASP) found a significant influence of the formation of the Pebas and Acre systems on the early diversification of these damselflies, though evidence for the influence of the rise of the different Andean ranges was mixed. Diversification rates have been uniform in all genera except one— Polythore —where a significant increase in the late Pliocene (~3 mya) may have been influenced by recent Andean uplift. Conclusion The biogeographical models implemented here suggest that the Pebas and Acre Systems were significant geological events associated with the diversification of this damselfly family; while diversification in the tree shows some correlation with mountain building events, it is possible that other abiotic and biotic changes during our study period have influenced diversification as well. The high diversification rate observed in Polythore could be explained by the late uplift of the Northern Andes. However, it is possible that other intrinsic factors like sexual and natural selection acting on color patterns could be involved in the diversification of this genus.
Antiviral effect of copper chloride on feline calicivirus and synergy with ribavirin in vitro
Authors: li dengliang , Cui Zhanding , Li Guohua , Zhang Liangting , Zhang Ying , Zhao Han , Zhang Shuang , Guo Yanbing , Zhao Yanli , Men Fanxing , Zhao Shihui , Shao Jiang , Du Dongju , Huang Hailong , Wang Kai , Hu Guixue , Li Tiansong , Zhao Yongkun 
Published: June 2020

Abstract
Background: Feline calicivirus (FCV) is a common and highly prevalent pathogen causing upper respiratory diseases in kittens and felines in recent years. Due to the substantial genetic variability of the viral genes, existing vaccines cannot provide complete protection. Therefore, research on FCV antiviral drugs has received much attention.Results: In this study, we found that copper chloride had dose-dependent antiviral effects on FCV in F81 cells. We also found that the combination of copper chloride and ribavirin had a synergistic protective effect against FCV in F81 cells. In contrast, the combination of copper chloride and horse anti-FCV immunoglobulin F(ab')2 showed an antagonistic effect, likely because copper chloride has an effect on F(ab')2 immunoglobulin; however, further research is needed to clarify this supposition.Conclusions: In summary, we found that copper chloride had low cytotoxicity and significant antiviral effects on FCV in F81 cells, providing a new drug candidate for the prevention and treatment of FCV infection.
General practice patients starting treatment for substance use problems: observations from two data sources across levels of care
Authors: Boffin Nicole , Antoine Jerome , Baelen Luk Van , Moreels Sarah , Doggen Kris 
Published: June 2020

Abstract
Background In Belgium, the incidence of treatment episodes for substance use problems is monitored by the Network of Sentinel General Practices (SGP), and at higher, specialist care levels by the Treatment Demand Indicator (TDI) surveillance. Using both data sources, we examine 1) how patients starting specialist treatment for substance use problems on referral by their GP compare to those that were referred by non-GP caregivers; 2) how patients starting GP treatment for substance use problems without receiving concurrent specialist treatment compare to those who did.Methods Both surveillances are based on the TDI protocol for reporting data to the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) on individuals starting treatment as a result of their substance use. Data from 2016 and 2017 were examined using 95% confidence intervals and multivariate logistic regression.Results According to TDI-data (n=16,543), determinants of being referred by a GP (versus by a non-GP caregiver) for specialist treatment were age ≥ median (OR 1.25; 95% CI 1.13-1.38), education ≥ secondary level (OR 1.27; 95% CI 1.15-1.41), recent employment (OR 1.71; 1.56-1.88), recent stable accommodation (3.62; 95% CI 3.08-4.26), first treatment episode (OR 1.72; 95% CI 1.57-1.87), recent daily primary substance use (OR 1.46; 95% CI 1.33-1.59) and mono substance use (OR 1.23; 95% CI 1.04-1.48). Type of substance use was a significant determinant with higher odds of using pharmaceuticals (and alcohol) (OR 1.24; 95% CI 1.04-1.48), and lower odds of using cannabis only/primarily (OR 0.73; 95% CI 0.62-0.86), with reference to street drugs minus cannabis only/primarily. According to SGP data (n=314), determinants of starting GP treatment without concurrent specialist treatment were recent employment (OR 2.58; 95% CI 1.36-4.91), first treatment episode (OR 2.78; 95% CI 1.39-5.55) and living in the Brussels or Walloon region (OR 1.97; 95% CI 1.06-3.66).Conclusions This study provides a useful insight into the general practice population treated for substance use problems. It shows that both surveillances consistently found a relatively favourable profile of general practice patients with substance use problems.