bluuebunny/crossref_metadata_2025_split huggingface dataset:
NATIONAL OR LOCAL POLITICAL PARTIES: THE DYNAMICS OF POLITICAL OPTIONS IN 2019 GENERAL ELECTIONS IN ACEH PROVINCE
Authors: Harahap Husnul Isa 
Published: August 2020

Purpose of the study: The objective of the study was to describe the distribution of votes for local and national political parties in each electoral district in Aceh Province, Indonesia, especially for local parliamentary elections (Aceh DPRD or DPRA).
Methodology: This is a descriptive study with a qualitative approach. Data collection n in this study uses the method of library research and documents (secondary data). Data analysis uses descriptive analysis based on the political behaviour approach.
Main Findings: The main findings of this study indicate that the distribution of votes for political parties in the 2019 elections has spread to both local and national parties. If quantified totally, the national party dominates the votes in each electoral district. But if the votes are described based on each political party, it will look different. There are no political parties that strongly dominate the vote. The existence of political parties that have local character or type has the same effect on voters compared to national parties.
Applications of this study: The theoretical implication of this study was to strengthen Kaare Strom’s theory about political party behavior. The behavior of political parties in elections is to obtain votes.
Novelty/Originality of this study: When national and local political parties compete in general elections, voters do not feel significant differences between the two political parties.
The eye status in patients after new coronavirus infection
Authors: Ryabtseva A. A. , Grishina E. E. , Andryukhina O. M. , Kovrizhkina A. A. , Andryukhina A. S. 
Published: August 2020

Rationale: The emerging new coronavirus infection caused by SARS-CoV-2 has resulted in a pandemic. Its clinical manifestations are highly variable and the death rate is high due to rapid progression to acute respiratory distress syndrome. Identified abnormalities of the eye are mainly related to conjunctival injury during manifestation of the disease.Aim: To study the eye abnormalities in patients who have undergone COVID-19.Materials and methods: Ophthalmological examination was performed in 23 patients (6 [26%] men and 17 [74%] women, median age 42.39 years) at days 44 to 85 after manifestation of COVID-19 infection in the Department of Ophthalmology, MONIKI. In addition to the standard ophthalmological examination, all patients were evaluated with optical coherence tomography (OCT), auto fluorescence, contrast and color sensitivity test with different light sources, and tear production assessment.Results: In the late convalescence period there were complaints of dry eyes and abnormal color perception, with visual acuity being unchanged. The OCT assessment the peripapillary retina identified small hyper-reflective foci in the inner layers.Conclusion: Eye disease in patients after COVID-19 is mainly related to the condition of the eye surface, abnormal color perception and abnormal architectonics of the inner retinal layers, which can persist for a long time during convalescence.
Dental anxiety and the effectiveness of local anesthesia
Authors: Esmaeili Hadi , Malekzadeh Mohammad , Esmaeili Davood , Nikeghbal Farid 
Published: August 2020

Aim: The successful anesthesia is an essential factor for dental treatment. This study aimed at determining the effectiveness of local anesthesia and it’s relationship with dental Anxiety. Methods: This cross-sectional study was carried out on 256 dental patients, in 2017. Dental Anesthesia was administered after completing the Modified Dental Anxiety Scale by the patients. The level of anesthesia was recorded in one of three states (successful, difficult, and failed). Collected data was analyzed using SPSS version 22 and tests of, Chi-square, independent t-test, analysis of variance, and logistic regression model. Results: About 60.5% subjects had moderate-severe dental anxiety. The mean of dental anxiety significantly was lower in the successful anesthesia group (P<0.01). Patients with elementary education had a significantly higher level of dental anxiety (P<0.01). Dental anxiety was significantly higher in the age group of ≥59 years, compared to the other age groups, except for 49-58 years (P<0.05). Subjects with a significantly higher level of dental anxiety more delayed their visits to the dentist. The logistic regression model showed that the dental anxiety (high anxiety) and literacy level (elementary) were the most important predictors of failed or difficult anesthesia. Conclusion: Informing patients about dental treatment procedures, regular and periodic visits to the dentist, using psychotherapeutic techniques to reduce dental anxiety before anesthesia, could play an important role in the success of anesthesia.
Komunikasi Interpersonal Pustakawan Dan Pemustaka Di Perpustakaan Universitas Islam Negeri Sumatera Utara Medan
Authors: Raudah Hildayati , Santi Triana 
Published: August 2020

<p><em>The research objective is to analyze librarian and library interpersonal communication in UINSU Medan. This study uses the effectiveness theory of interpersonal communication from Devito</em><em> (1986)</em><em>. This research method uses qualitative research methods with a phenomenological study approach. Research informants were 5 (five) librarians who worked in the UINSU library and 9 (nine) library users and through purposive sampling. Data collection techniques through observation, interviews, and documentation. Data analysis techniques use thematic analysis. Data triangulation was carried out to 9 (nine) students of UINSU Medan. The results showed that UINSU Medan library librarians had effective interpersonal communication found in several components, namely: 1)</em><em> </em><em>Verbal and Nonverbal Communication, 2) Openness, 3) Receiving Input, 4) Hospitality, 5) Empathy, 6) Support , 7) Familiarity, 8) Positive Thinking, 9) Respect. Barriers that occur in misperceptions, lack of sensitivity, lack of information instructions in the library.</em><em></em></p><p><em> </em></p><p><em><br /></em></p><p><em> </em></p>
Current Account Deficits and Sustainability in Africa: Evidence from Cointegration Approach
Authors: Kouassi Eugene , Kolotioloman Soro , Juana James Sharka 
Published: August 2020

Abstract
This paper gives an overview of current accounts sustainability in forty African countries over the 1980–2016 period. The paper goes through by testing if this sustainability depends on regional blocs, income levels or exchange rate regimes. For this purpose, the paper employs a formal theoretical framework, recent cointegration techniques like threshold cointegration to test for long-run relationship between variables. Results reveal that although exports and imports plus interest payments on external debt are cointegrated in African economies, the current accounts are weakly sustainable in 45% of African economies and unsustainable in only 8%. Among regional blocs, income level and exchange rate regime groupings, only exchange rate regime groupings have a significant eﬀect on current account sustainability. Since current account is strong sustainable in countries operating ﬂexible and intermediate exchange rate regimes than countries operating fixed regimes.JEL Codes: F32, C23, C22
Feasibility study of transfacet sacroiliac screw fixation based on Mimics
Authors: Din Yanping , Yin Qudong , Liu Shuai , Li Dong , Wu Yongwei , Jiang Yan 
Published: August 2020

Abstract
Background

Sacroiliac screw (SIS) has become an effective internal fixation method for sacral fracture and sacroiliac joint dislocation. However, classic placement of SIS has some defects such as possibility of nerve injury with a learning curve and contraindications. An alternative to the classic placement of SIS is expected

Objective

To explore the feasibility of transfacet sacroiliac screw (TFSIS), so as to provide an alternative to the classic placement of SIS.

Methods

CT scan data of pelvis in 60 healthy adults including 30 males and 30 females with an average age of 45 years (range 20-70 years), were transferred into a PC. The anatomical parameters of screw channel of TFSIS were measured by simulating the placement of TFSIS by Mimics 16.0 software on the PC. Secondly, according to the anatomical parameters of each pelvis, 5.0 mm and 6.0 mm screws were used respectively to simulate the placement of TFSIS in 30 pelvises to observe the effect of placement.

Results

The length of screw channel was (10.84 ± 0.93) cm, the distance between the insertion point and the center of the superior facet of S1 was (1.14 ± 0.93) mm, the distance between the exit point and the upper -posterior border of acetabulum was (5.73 ± 2.57) mm, the anteversion angle between the central axis of the screw channel and the line parallel to the upper endplate of S1 was (53.96±3.94) °, the outward angle between the central axial of the screw channel and the longitudinal axis of the trunk was (47.4 7± 5.13)°, the safety angle in sagittal plane was (13.91 ± 2.92) °, the safety angle in coronal plane was (8.57 ± 1.63) °, the height was (11.91 ± 1.47) mm, and the width was (7.75 ± 0.89) mm. Within the channel for 5.0mm and 6.0mm screws accounted for 100%.

Conclusions

Placement of TFSIS with a diameter of 5.0-6.0 mm and a length of 90 mm is safe and feasible, which may be used as an alternative to the classic placement of SIS.
The Bidirectional Relationship Between Cognitive Function and Loss Hierarchy of Activities of Daily Living Among Older Adults with Disabilities in China: A Cross-Lagged Analysis
Authors: Sun Qian , Jiang Nan , Lu Nan , Lou Vivian W. Q. 
Published: August 2020

Abstract
Background

The Chinese population is experiencing rapid aging, limitations in activities of daily living and decline in cognitive function among the oldest-old group causes tremendous economic, family and social burden. Examining their relationship is critically relevant for policymakers. The present study aimed to determine the bidirectional relationship between cognitive function and the loss hierarchy of activities of daily living among older adults in China.
Methods

Data were derived from a sample of 469 older adults who participated in both the 2010 and 2013 waves of a Longitudinal Study on Family Caregivers for Frail Older Adults. Cognitive function was assessed using the Chinese version of the Short Portable Mental Status Questionnaire and activities of daily living were measured by self-reports of having difficulty or needing help with basic daily activities. A cross-lagged analysis was adopted.
Results

In general, the results showed cognitive function in 2010 was a significant predictor of middle loss activities of daily living (dressing, moving, bathing and toileting) in 2013, and late loss activities of daily living (feeding and hygiene) in 2013. The loss hierarchy of activities of daily living among older adults was not shown to be significant as a risk factor of cognitive function in 2013.
Conclusions

The findings expanded understanding of the relationship between cognitive function and the loss hierarchy of activities of daily living as well as provided evidence for clinicians and service planners for anticipating the subsequent care and service needs of the elderly and their families.
Structural and dynamical analysis of integrated human/SARS-CoV-2 metabolic models present novel treatment strategies against COVID-19
Authors: Bannerman Bridget , Julvez Jorge , Oarga Alexandru , Moreno Pablo , Blundell Tom , Floto Andres 
Published: August 2020

Abstract
The coronavirus disease 2019 (COVID-19) pandemic caused by the new coronavirus (SARS-CoV-2) is currently responsible for over 500 thousand deaths in 216 countries across the world and is affecting over 10 million people. The absence of FDA approved drugs against the new SARS-CoV-2 virus has highlighted an urgent need to design new drugs. We developed an integrated model of the human cell and the SARS-CoV-2 virus to provide insight into the pathogenetic mechanism of the virus and to support current therapeutic strategies. We show the biochemical reactions required for the growth and general maintenance of the human cell, first of all, in its healthy state. We then demonstrate how the entry of the SARS-CoV-2 virus into the human cell causes biochemical and structural changes, leading to a change of cell functions or cell death. We have completed a comparative analysis of our model and other previously generated cell type models and highlight 48 pathways and over 800 reactions hijacked by the virus for its replication and survival. We designed a new tool which predicts 15 unique reactions as drug targets from our models (the integrated human macrophage, human airway epithelial cells and the SARS-CoV2 virus) and provide a platform for future studies on viral entry inhibition and drug optimisation strategies.
Development and Growth of Human Salivary Stones by Neutrophil Extracellular Traps
Authors: Schapher Mirco , Koch Michael , Weidner Daniela , Scholz Michael , Wirtz Stefan , Mahajan Aparna , Herrmann Irmgard , Singh Jeeshan , Knopf Jasmin , Leppkes Moritz , Schauer Christine , Grüneboom Anika , Alexiou Christoph , Schett Georg , Iro Heinrich , Munoz Luis , Herrmann Martin 
Published: August 2020

Abstract
Salivary gland stones, or sialoliths, are the most common cause of the obstruction of salivary glands. Symptomatic sialolithiasis has a prevalence of 0.45% in the general population, is characterized by recurrent painful periprandial swelling of the affected gland and often results in sialadenitis with the need for surgical intervention. The mechanism behind the formation of sialoliths has been elusive. Here we show that neutrophil extracellular traps (NETs) initiate the formation and growth of sialoliths. The deposition of neutrophil granulocyte extracellular DNA around small crystals results in their dense aggregation, and the subsequent mineralization creates alternating layers of dense mineral, predominantly calcium salt deposits and DNA. Further agglomeration and appositional growth of these structures promotes the development of macroscopic sialoliths that finally occlude the efferent ducts of the salivary glands, causing clinical symptoms and salivary gland dysfunction. These findings provide an entirely novel insight into the mechanism of sialolithogenesis in which an immune system mediated response essentially participates in the physico-chemical process of concrement formation and growth.
Tumour - Related Epilepsy and Post-Surgical Outcome: Tertiary Hospital Experience in Saudi Arabia
Authors: Alattas Alawi Aqel Aqel Abdullah , Al-Hindi Hindi , AbaAlkhail Tariq , Bawazir Amen , Aldhalaan Hesham , Althubaiti Ibrahim , Baz Salah 
Published: August 2020

Abstract
Background Some studies have suggested that tumor pathology significantly influence freedom from seizures post epilepsy surgery; however, there is no consensus among researchers regarding this issue. This study aims to retrospectively look for different types of tumor- related epilepsy and their outcomes in the first-year post epilepsy surgery among both adults and children. Methods In this hospital-based retrospective study, patients with drug resistant epilepsy due to brain tumor who underwent epilepsy surgery were included. Our patients underwent a thorough presurgical evaluation in an Epilepsy Monitoring Unit (EMU) before deciding to undergo surgical intervention, according to an epilepsy case-management conference. Four outcomes of interest were investigated during the first-year post epilepsy surgery.Results One hundred patients with brain tumors were included in this study (male: female = 3:2); 45 patients were children. Most of the patients (93) had low-grade gliomas or glioneuronal tumors (G/GNT). No significant differences in outcome were observed between sex, age, or histopathological categories. However, during the first year after epilepsy surgery most of the low-grade G/GNT cases showed favorable outcomes of International League Against Epilepsy (ILAE) class 1 and 2 (61.3% and 9.7%, respectively), while high-grade gliomas and meningothelial tumors showed outcomes of ILAE class 1 (40% and 100%, respectively). Conclusions One-year favorable outcome of post epilepsy surgery of different brain tumors have been achieved among both children and adults. Adequate presurgical evaluation in EMU (for long-term video-electroencephalography monitoring) to plan appropriate surgical strategy is advised. Tumor Pathology does not influence seizure outcome one-year post epilepsy surgery.
Trogloregions: delimiting subterranean faunistic identities in Afrotropics and Neotropics
Authors: Alvarenga Denizar , Silva Marconi , Ferreira Rodrigo 
Published: August 2020

Abstract
Studies regarding macroecological patterns involving subterranean fauna are challenging, since the environments where such species are found generally do not have the same ecological patterns observed on the surface, due to their isolation. Therefore, using data on the occurrence of invertebrate families, we tested the influence of ecological regions already established for surface environments (biogeographic domains, biomes, and ecoregions), lithology, and drainage basins as potential drivers of the similarity on the invertebrates communities. We observed that within the surface ecoregions there might still be subdivisions due to different drainage basins, a pattern that was repeated in both aquatic and terrestrial fauna. Thus, we present different bioregions in the Afrotropics and Neotropics, in which caves have distinct faunistic identities. We discuss the biogeographic relationships between the epigean and hypogean environments that may be behind these patterns. We believe that these results can assist in conservation strategies, in which these different compositions are considered.
N-CAM expression: The study of muscle disease in a tertiary center of Thailand
Authors: Laoyoung Kanyarat , Waisayarat Phu , Dejthevaporn Charungthai , Khongkhatithum Chaiyos , Waisayarat Jariya 
Published: August 2020

Abstract
Objectives To evaluate the correlation between N-CAM expression and diagnosis of common muscle diseases in the Thai population.Methods The expression of N-CAM was interpreted in 75 muscle biopsy specimens diagnosed with myopathies in a 3-year retrospective study. We used anti-CD56 (MRQ-42) rabbit monoclonal primary antibody (1:200, Cell Marque, MilliporeSigma, Rocklin, CA, USA) in our immunohistochemical study.Results Of our 75 patients, 41 cases were female and 34 were male. The mean age of the patients was 35-year-old, with the range from 3 months to 83 years. 35 (46.67%) of the specimens were N-CAM-positive, and 40 (53.33%) were N-CAM-negative. There were 35 (46.67%) cases diagnosed with nonspecific myopathy, 17 (22.67%) with inflammatory myopathy, 9 (12.00%) with neurogenic dystrophy, 7 (9.33%) with muscular dystrophy, 5 (6.67%) with non-diagnostic myopathy, and 2 (2.67%) with mitochondrial myopathy. Chi-squared testing was used to analyze the N-CAM expression data and the diagnosis. There is a statistically significant correlation between inflammatory myopathy and N-CAM positivity (p-value <0.001, OR 14.250, 95% CI 2.960-68.606), with 15 out of 17 cases being N-CAM-positive. N-CAM was also positive in muscular dystrophy, neurogenic myopathy, and nonspecific myopathy but they were not statistically significant. We did not find N-CAM expression in our 2 mitochondrial myopathy cases, nor in the 5 non-diagnostic myopathy cases.Conclusion N-CAM expression can be a complementary tool for diagnostic evaluation in muscle diseases with regeneration or denervation of muscle fibers. We recommend further study in a larger group.
Development of HPLC Based QuEChERS Method for High Recovery of Fungicides From Vegetable Samples
Authors: Majid Abdul , Ali Zeeshan , Husssain Dilshad , Sajid Muhammad 
Published: August 2020

Abstract
Vegetables are the most essential part of our diet. Several pesticides are used to kill the pests. These pest cause different diseases on vegetable plants. As a result of which they are getting more and more production of vegetables but there are many hazards for humans. To get rid of this problem, a simple QuEChERS method is used which is based on solvent extraction method in which different salts and acetonitrile were used. In this method clean-up process and extraction were important HPLC technique is used to determine the accurate results. Despicable recoveries of fungicides were ranges between 0.63% to 107.68% at spiking levels and at different factors through percentage RSD between 3.6% to 4.7%. LOD of two fungicides were in the range of 0.0021mg/kg to 0.00181mg/kg and LOQ of two fungicides were in the range of 0.0706mg/kg to 0.00606mg/kg. By varying many factors the recoveries of fungicides may vary. The recoveries of two fungicides may increase by increasing temperature, pH and concentration but decrease with the passage of time due to degradation of fungicides. By this QuEChERS method we get different concentration of fungicides in some vegetables but in Methi vegetables they are absent. And determinations and extraction of fungicides were completed by HPLC technique. QuEChERS method is very efficient and good method for determination of pesticides in various vegetables. Hence our experimental results were validated with this efficient method.
ADAM10 Plasma Levels Predict Worsening in Cognition of Older Adults: A 3-Year Follow-Up Study
Authors: Monteiro Maria Patricia A Oliveira , Oliveira Danielle S. M. Salheb , Manzine Patricia Regina , Nascimento Carla Manuela Crispim , Orlandi Ariene A. dos Santos , Gomes Grace A. de Oliveira , Orlandi Fabiana dos Santos , Zazzetta Marisa Silvana , Pott Henrique , Cominetti Marcia Regina 
Published: August 2020

Abstract
Background

Blood-based biomarkers for Alzheimer’s disease (AD) are highly needed in clinic practice. So far, the gold standards for AD diagnosis are brain neuroimaging and beta-amyloid peptide, total tau and phosphorylated tau in cerebrospinal fluid (CSF), however, they are not attractive for large-scale screening. Blood-based biomarkers will allow an initial large-scale screening of patients under suspicion that could later be tested for the already established CSF biomarkers. To this regard, we and other research groups have already described that the plasma and platelet levels of ADAM10 are higher or lower, respectively, in patients with AD, compared to those cognitively healthy.
Methods

This was a three-year longitudinal cohort study that included 219 community-dwelling older adults. Sociodemographic, clinical, lifestyle, depressive symptoms (GDS) and cognitive data (Mini-Mental State Examination, MMSE; Clock Drawing test, CDT) were gathered. The measurement of ADAM10 plasma levels was performed using a sandwich ELISA kit. Bivariate comparisons between groups were performed using Wilcoxon-Mann-Whitney for continuous data and Pearson’s chi-square tests with Yates continuity correction, for categorical data. Longitudinal analyzes of changes in the MMSE score were performed using Linear Mixed-Effects modeling.
Results

Baseline MMSE score and ADAM10 values were significantly associated with MMSE score values on the follow-up assessment. When analyzing the interaction with time, having a normal MMSE at baseline and ADAM10 plasma levels presented a significant and independent negative association with MMSE score values on the follow-up assessment. The analyses also showed that the effect of ADAM10 plasma levels on decreasing MMSE score values on follow-up seems to be more pronounced in those with normal MMSE at baseline. Taken together, these results provide the first direct evidence that changes in ADAM10 plasma levels are predictors of cognitive worsening in older adults.
Conclusions

Considering that ADAM10 increase in plasma is detected as soon as in mild cognitive impairment (MCI) patients, the results presented here may support the complementary clinical use of this biomarker, in addition to the classical AD biomarkers. Moreover, this work can shed light on the study of blood biomarkers for AD and contribute to the advancement of the area.