bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pulmoner Arteriyal Hipertansiyon Hastalarında Serum D vitamini Düzeyleri
Authors: SİNAN Ümit Yaşar , CANBOLAT İsmail Polat , KAYA Ayşem , KÜÇÜKOĞLU Mehmet Serdar 
Published: March 2020

Amaç: Pulmoner arteriyal hipertansiyon (PAH) hastalarında D vitamini düzeylerinin sağlıklı gönüllülerden oluşan kontrol grubuyla kıyaslanması ve hastalık şiddetiyle D vitamini düzeyi arasındaki ilişkinin araştırılması.
Yöntemler: Çalışmamız tek merkezli, kesitsel bir çalışma olup, pulmoner hipertansiyon (PH) polikliniğimizde PAH tanısı ile takip edilen 36 hasta ve yaş-cinsiyet eşleştirilmiş 24 sağlıklı gönüllüden oluşmaktadır. PAH tanısı, güncel Avrupa Kardiyoloji Cemiyeti ve Avrupa Solunum Derneği 2015 PH kılavuzu tanı algoritması önerileri doğrultusunda konuldu. Kontrol grubu olarak, bilinen bir kardiyak veya sistemik-enflamatuvar hastalık öyküsü olmayan, herhangi bir ilaç kullanmayan, tüm sistem fizik muayenesi normal, elektrokardiyografik (EKG) ve ekokardiyografik (Eko) incelemede patoloji saptanmayan sağlıklı gönüllüler seçildi. Tüm hastalarda ve sağlıklı gönüllülerde sabah 8 saat açlık kan örnekleri alınarak, plazma 25-OH vitamin D düzeyleri ölçüldü (Elecsys® Vitamin D Testi).
Bulgular: Çalışma popülasyonumuz 36 PAH hastası ve yaş-cinsiyet eşleştirilmiş 24 sağlıklı gönüllüden oluşmaktaydı. Hastaların 24 tanesinde (%67) doğumsal kalp hastalığıyla ilişkili PAH (PAH-DKH), 12 tanesinde (%33) idiyopatik PAH (IPAH) mevcuttu. Tüm çalışma grubunun yaş ortalaması 41.4 ± 14.0 iken PAH hastaları ve kontrol grubunda yaş ortalaması benzerdi (median 42 & 40 yaş). Her iki grupta da kadın cinsiyet baskındı. Sağlıklı gönüllüler ve PAH hastaları arasında vücut kitle indeksi, kreatinin, ürik asit, hematokrit düzeyi açısından bir fark yoktu. Vitamin D düzeyleri ise PAH hastalarında (7.7 ± 6.2 U/L) sağlıklı gönüllülere göre (21.9 ± 14.1 U/L) belirgin olarak düşük saptandı (p
Normotermik Kardiyopulmoner Bypass Sırasında Enflamasyon Parametrelerindeki Değişiklikler İle Oksidatif Stresin Değerlendirilmesi
Authors: AKÇA Esin , AYDIN Mehmet Salih , PADAK Mahmut , GÖZ Mustafa , DİKME Reşat , GÖÇ Ömer 
Published: March 2020

Amaç: Bu çalışmanın amacı, kardiyopulmoner bypass (KPB) ameliyatına giren hastalardan belirli aralıklarla alınan kanın serumundaki CRP, seruloplazmin ve TAS (total antioksidan seviye), TOS (total oksidan seviye), OSİ (oksidatif stres indeksi) seviyelerini ölçerek bir değerlendirmenin yapılması amaçlanmıştır.
Yöntemler: Çeşitli sebeplerden dolayı KPB cerrahisi ile ameliyat olan hastalardan ameliyat öncesi, pompaya (kalp akciğer makinesi) giriş, kross klemp sonrası ve protamin verilmesi sonrası olmak üzere 4 jelsiz tüpe kan alınarak bir çalışma grubu oluşturulmuştur. Alınan kanlar santrifüjde ayrıştırıldıktan sonra plazmaları -80 °C’de saklanmıştır. Numuneler çalışma gününde otoanalizör cihazında çözülerek serum Seruloplazmin, C-Reaktif Protein (CRP), TAS, TOS ve OSİ kolorimetrik yöntemle ölçülmüştür.
Bulgular: TAS değeri; ameliyat öncesi 0.95 ± 0.19, pompaya giriş 0.73 ± 0.13, kross klemp sonrası 0.84 ± 0.18, protamin sonrası 0.92 ± 0.14 ve p
Ocorrência de fungos micorrízicos arbusculares em um plantio de cupuaçu na estrada de Balbina, Amazonas
Authors: Rocha Luzia Pontt Melo , Moreira Francisco Wesen , Oliveira Cassiane Minelli de , Oliveira Luiz Antonio de 
Published: March 2020

Cerca de 90% dos solos amazônicos são ácidos e de baixa fertilidade, pobres em nitrogênio e fósforo, além de apresentarem toxidez de alumínio, o que limita o seu uso na agricultura regional. Considerando-se o alto custo dos adubos e outros insumos, além das dificuldades de transporte pelos agricultores regionais, os sistemas agrícolas regionais precisam ser redirecionados com vistas a dar à população regional, maior independência em produtos básicos sem causar danos aos ecossistemas. Deste modo, associações micorrízicas do tipo arbuscular, constituem uma alternativa de grande importância para minimizar o uso de fertilizantes, por ajudarem as plantas a explorarem melhor o solo. Os benefícios da simbiose para o hospedeiro resultam de melhorias no estado nutricional da planta, melhor utilização e conservação de nutrientes no sistema, redução de perdas por estresses de natureza biótica ou abiótica. O objetivo deste estudo foi avaliar o efeito do carvão vegetal, adubação química e orgânica do solo na colonização micorrízicas no cupuaçu. O trabalho foi desenvolvido no Km 42 da estrada de Balbina em Presidente Figueiredo no Amazonas. Foram feitas duas coletas de folhas, raízes e solos, uma na época da seca e outra na das chuvas, usando quatro tratamentos com três repetições. Os fungos micorrízicos arbusculares foram avaliados pelo método de clareamento e coloração das raízes. O solo, nos tratamentos com calagem, apresentou maiores teores de Ca e Mg, mas sem reduzir os teores elevados de Al e acidez. A adubação com K e P elevou os teores desses elementos no solo e os de Fe e Zn, que devem estar presentes como traços nos adubos de K e P adicionados. As colonizações radiculares por fungos micorrízicos arbusculares foram baixas nas duas coletas realizadas, sendo menor na época chuvosa. A contribuição da simbiose plantas-fungos micorrízicos para a nutrição das plantas foi afetada, devido à baixa ocorrência dos fungos nas raízes. Esporos do gênero Glomus sp foram os que mais ocorreram nos solos, seguidos pelos do gênero Scutellospora sp.
Pronunciamientos oficiales sobre documentación fílmica
Authors: Domínguez-Delgado Rubén , López-Hernández María-Ángeles 
Published: March 2020

Se hace un recorrido histórico por las diversas intervenciones de los organismos públicos internacionales, especialmente europeos, en el ámbito de la documentación fílmica, desde la gestación, durante la década de los años setenta del siglo XX, de las Recomendaciones para la Salvaguarda y Conservación de las Imágenes en Movimiento publicadas por la Unesco en 1980 hasta la actualidad. En los dictámenes fijados por estos organismos oficiales se abordan diferentes asuntos de interés relacionados con la preservación, gestión documental y accesibilidad del patrimonio cinematográfico.
A historical journey is made through the various interventions of international public organizations, especially European, in the field of film librarianship, from the gestation, during the decade of the seventies of the twentieth century, of the Recommendations for the Safeguarding and Conservation of the Moving Images published by Unesco in 1980 to the present. In the dispositions dictated by these official organizations different matters of interest related to the preservation, treatment and accessibility of the film heritage are approached.
Análisis de los principios para la descripción de datos de investigación mediante Datacite Metadata Schema
Authors: Ávila-Barrientos Eder 
Published: March 2020

El objetivo de este trabajo consiste en analizar los principios teórico-metodológicos relacionados con la descripción de los datos de investigación. Se realizó un análisis sobre el estado de la cuestión de los datos de investigación, en cual se abordan aspectos de su citación, descripción y sistematización. Se identificaron y analizaron los elementos de metadatos para la descripción de conjuntos de datos de investigación que se incluyen en el DataCite Metadata Schema, con el propósito de crear una propuesta de perfil descriptivo aplicable a estos conjuntos. Se estima que, si los datos de investigación se encuentran debidamente descritos, entonces se fomentará en mayor grado su accesibilidad y reutilización. Para ello, es necesario que las instituciones académicas y de investigación participen en la generación de políticas de acceso abierto a sus datos de investigación.
The objective of this work is to analyze the theoretical-methodological principles related to the description and accessibility of research data. Hermeneutics and discourse analysis were applied to literature specialized in: research data; access and description of research data; data repositories. Metadata elements for the description of research datasets that are included in the DataCite Metadata Schema were identified and analyzed, in order to create a descriptive profile proposal for research data sets, which can be applied in the data repositories. If the research data is properly described, then its accessibility and reuse will be further promoted. To do this, it is necessary for academic and research institutions to participate in the generation of open access policies for their research data.
The Editor’s recommendation of this issue’s article to readers
Authors: BULDUR Burak 
Published: March 2020

I am pleased to inform you that I have chosen this article by Koruyucu et al.1 as Editor’s Choice for first issue of 2020.
Biofilm control is an important procedure for the removal of microbial dental biofilm to prevent tooth decay and periodontal disease and to prevent the accumulation of teeth and adjacent gingival surfaces. Toothpastes with antimicrobial effects have an important effect on the removal of both dental biofilm and gingivitis.
This article shows that all tested toothpastes including fluoride-free, chlorite-containing and fluoride-containing, proved to be safe and significantly effective clinical and microbiological features
Happy readings and have a great year with increasing academic interest in 2020!
Predictive value of CONUT score combined with serum CA199 levels in postoperative survival of patients with pancreatic ductal adenocarcinoma: a retrospective study
Authors: Wang Ankang , Sun Bo , Wang Min , Shi Hao , Huang Zhiwei , He Tao , Li Qiu , Deng Jiaqi , Fu Wenguang , Jiang Yu 
Published: March 2020

Background
The preoperative controlling nutritional status (CONUT) score and serum carbohydrate antigen 199 (CA199) levels are individually correlated with the prognosis of pancreatic ductal adenocarcinoma (PDAC). The objective of this study aimed to investigate the efficacy of CONUT score and CA199 (CONUT-CA199) combination in predicting the prognosis of PDAC patients undergoing radical surgery.

Methods
We retrospectively analyzed the preoperative CONUT scores and serum CA199 levels of 294 patients with PDAC who underwent radical resection at the Affiliated Hospital of Southwest Medical University between March 2012 and July 2019. Patients were divided into four groups on the basis of their preoperative CONUT scores and serum CA199 levels: CONUTlow/CA199low (1), CONUTlow/CA199high (2), CONUThigh/CA199low (3) and CONUThigh/CA199high (4). The prognostic effects were compared among the groups.

Results
CONUThigh was more frequent in patients with positive peripancreatic infiltration and Clavien–Dindo classification of ≥IIIa (P < 0.001). Kaplan–Meier analysis revealed obvious difference in overall survival (OS) and recurrence-free survival (RFS) among patients with PDAC having CONUT-CA199 scores of 1, 2, 3 and 4 (P < 0.001). Peripancreatic infiltration, lymph node metastasis, pTNM stage, CONUT score, serum CA199 levels and CONUT-CA199 classification were found to be the independent prognostic factors for OS and RFS in multivariate analyses. In time-dependent receiver operating characteristic (ROC) analyses, the area of the CONUT-CA199 score under the ROC curve (AUC) was higher than that of the preoperative CONUT score or serum CA199 levels for the prediction of OS and RFS.

Conclusion
CONUT-CA199 classification may be more effective in predicting the postoperative prognosis of PDAC patients.
Transcription levels and prognostic significance of the NFI family members in human cancers
Authors: Li Yuexian , Sun Cheng , Tan Yonggang , Li Lin , Zhang Heying , Liang Yusi , Zeng Juan , Zou Huawei 
Published: March 2020

Background
The nuclear factor I (NFI) is a family of transcription factors consisting of four distinct but closely related genes, NFIA, NFIB, NFIC and NFIX, which are important in the development of various tissues and organs in mammals. Recent study results have shown that NFI family may play a critical role in the progression of various human tumors and have been identified as key tumor suppressors and oncogenes for many cancers. However, the expression levels and distinctive prognostic values of the NFI family remain poorly explored in most cancers.

Materials and Methods
In the present study, the differences in mRNA expression of the NFI family in various cancers were investigated using the Oncomine and TCGA databases, and the mRNA expression, genetic alteration and DNA methylation of the NFI family members in various cancers were examined using cBioPortal for Cancer Genomics. In addition, the prognostic significance of the NFI family was assessed in multiple cancers using the Kaplan–Meier plotter (KM plotter) and SurvExpress databases.

Results
The mRNA expression levels in the NFI family were significantly downregulated in most cancers compared with normal tissues and DNA hypermethylation might downregulate the NFI family expression. Although NFIX expression was not downregulated in kidney, colorectal and prostate cancers. Furthermore, NFIB expression was upregulated in gastric cancer. Further survival analyses based on the KM plotter and SurvExpress databases showed dysregulations of the NFI genes were significantly correlated with survival outcomes in breast, lung, and head and neck cancers. Decreased expression levels of NFIA, NFIB and NFIC were associated with poor overall survival (OS) in head and neck cancer. Low mRNA expression of NFIA and NFIB was significantly associated with OS and first progression in lung adenocarcinoma, but not in lung squamous cell carcinoma. In addition, potential correlations between NFI family members and survival outcomes were also observed in liver, esophageal, kidney and cervical cancer.

Conclusion
The results from the present study indicated certain members of the NFI family could be promising therapeutic targets and novel prognostic biomarkers for human cancers.
Worth of Celebrity Attributes on Purchasing Behaviour of Assurance Service in Sri Lanka: Mediating Effect of Source Credibility
Authors: Sachitra K. M. V. , Poornima A. K. G. 
Published: March 2020

Purpose: Celebrity endorsement has been investigated in prior studies regarding various behavioural and cognitive aspects about consumer purchasing behaviour, it is not clear whether principles findings in the general celebrity literature can be directly applied to the service context. This study examines the effects of different attributes associated with celebrities on purchasing behaviour of life insurance policy in Sri Lanka.
Design: The study used a deductive approach and quantitative research design. Data were collected from 150 life insurance policy holders who representing four insurance companies in Sri Lanka. A self-administrated structured questionnaire was used to collect data. The step-wise multiple regression and regression-based path analysis were employed to test the hypotheses.
Findings: The study finds that celebrity attractiveness, trustworthiness and expertise have significant influence over purchasing behaviour and however the influence is not strong. Further, celebrity trustworthiness has a significant mediating effect on the relationship between celebrity expertise and buying behaviour.
Originality: Despite the role of celebrity attributes in influencing the buying behaviour of tangible products, limited studies have been conducted specifically on intangible products and also, the literature is not clear whether principle findings in the general celebrity can be directly applied to the intangible product or service context. This study has addressed that empirical gap.
Safety Considerations with Lithium‐Ion Batteries
Authors: Garche Jürgen , Brandt Klaus 
Published: March 2020

AbstractSafety is an unconditional requirement for acceptance of all batteries in the market. Like all energy‐storage systems, Li‐ion batteries carry the risk of an uncontrolled release of the stored energy. The risks that need to be considered are of chemical, thermal, kinetical, and mechanical nature. Dangers can be the release of toxic gases, explosions, and high‐voltage shocks. The level of risk at the cell level depends on the cell chemistry, especially the choice of cathode, anode, and electrolyte materials. Triggers of safety incidences can be of external nature such as an overcharge, or internal to the cell such as an internal short. Larger batteries must be able to avoid the propagation of a catastrophic failure of one cell to the whole system. Standardized safety testing is required to assess the response of the battery to these triggers, and to assure that this response is within the safe limits defined by the applicable regulations. Users must also contribute to safety by avoiding serious misuse and abuse of batteries. Despite this effort of all concerned, safety events cannot be avoided completely. When these occur, certain rules must be followed to control the risk and minimize the damage that might result from the catastrophic battery failure. Fires that might result from a safety incident must be fought with the correct measures.
High‐Temperature Battery Technologies: Na‐S
Authors: Palomares Verónica , Hueso Karina B. , Armand Michel , Rojo Teófilo 
Published: March 2020

AbstractSodium–sulfur (Na‐S) battery technology is one of the most developed types of high‐temperature battery, due to its considerable potential for energy storage and load leveling in power systems. These systems are eligible for use in large‐scale energy storage system applications due to their outstanding energy density, high efficiency of charge/discharge, low materials cost, and long life cycle of up to 15 years. However, several challenges must be overcome to ensure the safe operation of Na‐S batteries – mostly related to the reduction of the high operation temperatures. For this purpose, it is critical to develop new solid electrolytes with high ionic conductivity at room temperature. Taking this into account, ceramic/polymer composites are good candidates to achieve this goal. However, it is important to note an increase of capacity and cyclability is also desirable for Na‐S technology, and one of the strategies used to address this issue is the use of nanostructured carbon to host sulfur or to bind it to a polymer. Since the inception of Na‐S technology in the mid‐1970s, several patents have been developed. Analysis of these patents indicate that, on the one hand they aim to integrate these systems into the electrical grid to compensate the fluctuations of power demand and supply, especially of renewable energies, while on the other hand they show battery component improvements to achieve lower operating temperatures.
Pure CuBi2O4 Photoelectrodes with Increased Stability by Rapid Thermal Processing of Bi2O3/CuO Grown by Pulsed Laser Deposition
Authors: Gottesman Ronen , Song Angang , Levine Igal , Krause Maximilian , Islam A. T. M. Nazmul , Abou‐Ras Daniel , Dittrich Thomas , van de Krol Roel , Chemseddine Abdelkrim 
Published: March 2020

AbstractA new method for enhancing the charge separation and photo‐electrochemical stability of CuBi2O4 photoelectrodes by sequentially depositing Bi2O3 and CuO layers on fluorine‐doped tin oxide substrates with pulsed laser deposition (PLD), followed by rapid thermal processing (RTP), resulting in phase‐pure, highly crystalline films after 10 min at 650 °C, is reported. Conventional furnace annealing of similar films for 72 h at 500 °C do not result in phase‐pure CuBi2O4. The combined PLD and RTP approach allow excellent control of the Bi:Cu stoichiometry and results in photoelectrodes with superior electronic properties compared to photoelectrodes fabricated through spray pyrolysis. The low photocurrents of the CuBi2O4 photocathodes fabricated through PLD/RTP in this study are primarily attributed to their low specific surface area, lack of CuO impurities, and limited, slow charge transport in the undoped films. Bare (without protection layers) CuBi2O4 photoelectrodes made with PLD/RTP shows a photocurrent decrease of only 26% after 5 h, which represents the highest stability reported to date for this material. The PLD/RTP fabrication approach offers new possibilities of fabricating complex metal oxides photoelectrodes with a high degree of crystallinity and good electronic properties at higher temperatures than the thermal stability of glass‐based transparent conductive substrates would allow.
Observation of Unconventional Dynamics of Domain Walls in Uniaxial Ferroelectric Lead Germanate
Authors: Bak Ohheum , Holstad Theodor S. , Tan Yueze , Lu Haidong , Evans Donald M. , Hunnestad Kasper A. , Wang Bo , McConville James P. V. , Becker Petra , Bohatý Ladislav , Lukyanchuk Igor , Vinokur Valerii M. , van Helvoort Antonius T. J. , Gregg J. Marty , Chen Long‐Qing , Meier Dennis , Gruverman Alexei 
Published: March 2020

AbstractApplication of scanning probe microscopy techniques such as piezoresponse force microscopy (PFM) opens the possibility to re‐visit the ferroelectrics previously studied by the macroscopic electrical testing methods and establish a link between their local nanoscale characteristics and integral response. The nanoscale PFM studies and phase field modeling of the static and dynamic behavior of the domain structure in the well‐known ferroelectric material lead germanate, Pb5Ge3O11, are reported. Several unusual phenomena are revealed: 1) domain formation during the paraelectric‐to‐ferroelectric phase transition, which exhibits an atypical cooling rate dependence; 2) unexpected electrically induced formation of the oblate domains due to the preferential domain walls motion in the directions perpendicular to the polar axis, contrary to the typical domain growth behavior observed so far; 3) absence of the bound charges at the 180° head‐to‐head (H–H) and tail‐totail (T–T) domain walls, which typically exhibit a significant charge density in other ferroelectrics due to the polarization discontinuity. This strikingly different behavior is rationalized by the phase field modeling of the dynamics of uncharged H–H and T–T domain walls. The results provide a new insight into the emergent physics of the ferroelectric domain boundaries, revealing unusual properties not exhibited by conventional Ising‐type walls.
Metamaterials for Enhanced Optical Responses and their Application to Active Control of Terahertz Waves
Authors: Lee Seojoo , Baek Soojeong , Kim Teun‐Teun , Cho Hyukjoon , Lee Sangha , Kang Ji‐Hun , Min Bumki 
Published: March 2020

AbstractMetamaterials, artificially constructed structures that mimic lattices in natural materials, have made numerous contributions to the development of unconventional optical devices. With an increasing demand for more diverse functionalities, terahertz (THz) metamaterials are also expanding their domain, from the realm of mere passive devices to the broader area where functionalized active THz devices are particularly required. A brief review on THz metamaterials is given with a focus on research conducted in the authors' group. The first part is centered on enhanced THz optical responses from tightly coupled meta‐atom structures, such as high refractive index, enhanced optical activity, anomalous wavelength scaling, large phase retardation, and nondispersive polarization rotation. Next, electrically gated graphene metamaterials are reviewed with an emphasis on the functionalization of enhanced THz optical responses. Finally, the linear frequency conversion of THz waves in a rapidly time‐variant THz metamaterial is briefly discussed in the more general context of spatiotemporal control of light.