bluuebunny/crossref_metadata_2025_split huggingface dataset:
IMPACT OF PATIENT COUNSELING ON HEALTH KNOWLEDGE AND MEDICATION ADHERENCE IN ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS
Authors: P UNNATI , S ANUSHREYA , KEERTHANA G GABRIELA , P MOUNICA 
Published: May 2020

Objective: This study evaluated the impact of clinical pharmacist-led intervention in health knowledge and medication adherence of Asthma and chronic obstructive pulmonary disease (COPD) patients.
Methods: Questionnaires were designed to assess Health knowledge for Asthma and COPD separately. Medication adherence was measured by using the Morisky Medication Adherence Scale-8. Pre-counseling patient responses were recorded. Patient counseling was given regarding the disease condition, medications, and medication use at baseline visit. Patient responses were re-measured upon follow-up visit. The data extracted were tabulated, statistically analyzed and the results were obtained.
Results: A total of 141 patients completed the study. Before counseling, the mean (±standard deviation) of knowledge and adherence levels were found to be 8.51±3.36 and 5.01±2.11, respectively. After counseling, they increased up to 12.72±2.16 for knowledge (p<0.0001) and 6.60±1.35 (p<0.0001) for medication adherence. The majority of subjects had about 11–30% increase in knowledge as well as medication adherence. Male patients were more adherent to their medication regime than females.
Conclusion: The study demonstrates the positive impact of education and counseling provided by a clinical pharmacist in achieving better therapeutic outcomes – through improvement in medication adherence and health knowledge. In conclusion, continuous education programs and patient counseling should be conducted for chronic diseases to reiterate the importance of medication adherence and, in turn, prevent recurrences, arrest disease progression, minimize hospitalization, and ultimately improve quality of life.
PRODUÇÃO DO ESPAÇO, AUTOGESTÃO, COMUNIDADE E ESTADO: PROVOCAÇÕES A PARTIR DE KARL MARX
Authors: Ferreira Álvaro 
Published: May 2020

Resumo: O objetivo deste artigo é analisar, a partir de certas obras de Karl Marx, a construção de possibilidades para além do que se tem apresentado sobre a produção do espaço, com o fim de que esta se dê com mais justiça social. Discorre-se assim sobre ferramentas políticas e de gestão existentes, mas também, e principalmente, de outras possibilidades que remetem a “um impossível possível”, nos termos de Henri Lefebvre. Para tanto, são trazidas para o debate as noções de comunidade, verdadeira democracia, autodeterminação, autogoverno, autoemancipação e autogestão, tal como veiculadas na obra de Karl Marx.Palavras-chave: Produção do espaço. Estado. Comunidade. Autogestão. Karl Marx. GPRODUCTION OF SPACE, SELF-MANAGEMENT, COMMUNITY AND STATE: PROVOCATIONS FROM THE KARL MARX WORKAbstract: From certain works of Karl Marx, the article deals with an analysis of the construction of possibilities beyond what exists, for the purpose that the production of space brings social justice. We will discuss existing policies and management tools, but also and especially the other possibilities, referring to an “impossible possible”, in Henri Lefebvre’s terms. Therefore, we will bring to the debate the notions of community, true democracy, self-determination, self-government, self-emancipation and self-management based on Karl Marx´s theory.Keywords: Production of space. State. Community. Self-management. Karl Marx. PRODUCCIÓN DEL ESPACIO, AUTOGESTIÓN, COMUNIDAD Y ESTADO: PROVOCACIONES A PARTIR DE KARL MARXRsumen: El objetivo de este artículo es analizar, a partir de ciertos trabajos de Karl Marx, la construcción de posibilidades más allá de lo que existe, con el fin de que la producción del espacio se dé con más justicia social. Por lo tanto, hablamos de las herramientas políticas y de gestión existentes, pero también, y principalmente, de otras posibilidades que se refieren a “un imposible posible”, según Henri Lefebvre. Para ello, traemos para el debate las nociones de comunidad, verdadera democracia, autodeterminación, autogobierno, autoejecutación y autogestión basadas en el trabajo de Karl Marx.Palabras clave: Producción del espacio, Estado. Comunidad. Autogestión. Karl Marx.
O FUNDO PARA A CONVERGÊNCIA ESTRUTURAL DO MERCOSUL (FOCEM): UM DEBATE SOBRE ASSIMETRIAS E INTEGRAÇÃO REGIONAL
Authors: Oliveira Cruz Dayana Aparecida Marques de 
Published: May 2020

Resumo: As assimetrias e descompassos econômicos do Mercado Comum do Sul (MERCOSUL) trouxeram à tona a necessidade de compensar os ganhos econômicos para os membros menores do bloco e impulsionar o incremento técnico nas redes de infraestruturas (transportes e energia). Como resultado das discussões sobre o tema, foi criado o Fundo para a Convergência Estrutural do MERCOSUL (FOCEM), a fim de garantir o aprofundamento da integração regional no bloco. Após quinze anos de sua criação, alguns aspectos necessitam ser debatidos, sobretudo em relação aos critérios territoriais para o financiamento dos projetos e sua complexidade regional. Palavras-chave: Integração regional; Assimetrias; MERCOSUL; FOCEM; Projetos. MERCOSUR STRUCTURAL CONVERGENCE FUND (FOCEM): A DEBATE ON ASYMMETRIES AND REGIONAL INTEGRATIONAbstract: The economic asymmetries and mismatches of the Southern Common Market (MERCOSUR) has brought the need to compensate the economic gains for the smaller members of the bloc and boost the technical increase in infrastructure networks (transport and energy). As a result of the discussions on the subject, the MERCOSUR Structural Convergence Fund (FOCEM) was created to ensure a deepening of regional integration in the bloc. Fifteen years after its creation, some aspects need to be debated, especially in relation to the territorial criteria for the financing of the projects and their regional complexity.Keywords: Regional integration; Asymmetries; MERCOSUR; FOCEM; Projects. FUNDO DE CONVERGÊNCIA ESTRUTURAL DO MERCOSUL (FOCEM): UM DEBATE SOBRE ASSIMETRIAS E INTEGRAÇÃO REGIONALResumen: Las asimetrías y los desajustes económicos del Mercado Común del Sur (MERCOSUR) pusieron de manifiesto la necesidad de compensar las ganancias económicas para los miembros más pequeños del bloque e impulsar el aumento técnico de las redes de infraestructura (transporte y energía). Como resultado de las discusiones sobre el tema, se creó el Fondo para la Convergencia Estructural del MERCOSUR (FOCEM) para garantizar la profundización de la integración regional en el bloque. Quince años después de su creación, es necesario debatir algunos aspectos, especialmente en relación con los criterios territoriales para financiar los proyectos y su complejidad regional.Palabras-clave: Integración regional; Asimetrías; MERCOSUR; FOCEM; Proyectos.
Balance de las políticas de fomento para la producción de contenidos de ficción en alta definición en la Argentina (2011-2015)
Authors: Carboni Ornela 
Published: May 2020

Desde el enfoque de la economía política de la comunicación, este estudio analiza, en el período 2011-2015, las políticas de fomento a la producción de contenidos de ficción, en el marco de la aplicación de la Ley 26.522 de Servicios de Comunicación Audiovisual y de la implementación de la Televisión Digital Abierta (TDA).
Investigation of the effects of an ultraviolet germicidal irradiation system on concentrations of aerosolized surrogates for common veterinary pathogens
Authors: Pearce-Walker Jennifer I. , Troup Daniel J. , Ives Rebecca , Ikner Luisa A. , Rose Joan B. , Kennedy Melissa A. , Verhougstraete Marc P. 
Published: May 2020

Abstract

OBJECTIVE
To determine whether exposure to UV germicidal irradiation (UVGI) reduces concentrations of viable aerosolized microorganisms (attenuated strains of common veterinary pathogens) in a simulated heating, ventilation, and air conditioning (HVAC) system.

SAMPLE
42 air samples seeded with bacteriophage MS2 or attenuated strains of Bordetella bronchiseptica, feline calicivirus, feline herpesvirus-1, canine parvovirus, or canine distemper virus (6/microorganism) or with no microorganisms added (6).

PROCEDURES
A simulated HVAC unit was built that included a nebulizer to aerosolize microorganisms suspended in phosphate-buffered water, a fan to produce airflow, 2 UVGI bulb systems, and an impinger for air sampling. Ten-minute trials (3 with UVGI, 3 without UVGI, and 1 negative control) were conducted for each microorganism. Impingers collected microorganisms into phosphate-buffered water for subsequent quantification with culture-based assays. Results for samples yielding no target microorganisms were recorded as the assay's lower limit of detection. Statistical analysis was not performed.

RESULTS
The UVGI treatment resulted in subjectively lower concentrations of viable MS2, B bronchiseptica, and canine distemper virus (arithmetic mean ± SD log10 microorganism reduction, 2.57 ± 0.47, ≥ 3.45 ± 0.24, and ≥ 1.50 ± 0.25, respectively) collected from air. Feline herpesvirus-1 was detected in only 1 sample without and no samples with UVGI treatment. Feline calicivirus and canine parvovirus were not detectable in any collected samples.

CONCLUSIONS AND CLINICAL RELEVANCE
Results for some surrogates of veterinary pathogens suggested a potential benefit to supplementing manual disinfection practices with UVGI-based air cleaning systems in animal care environments. Further research is needed to investigate the utility of UVGI in operating HVAC systems.
Establishment of a method for evaluation of the efficacy of a classical swine fever virus subunit vaccine in rabbits
Authors: Cao Zhi , Zhang Heng , Yang Qian , Zhang Hui , Fan Gencheng 
Published: May 2020

Abstract

OBJECTIVE
To establish a method for evaluation of the efficacy of a classical swine fever virus (CSFV) subunit vaccine in rabbits as determined via humoral immune responses to the virus.

ANIMALS
40 specific pathogen–free rabbits.

PROCEDURES
Rabbits were randomly assigned to 4 groups (10 rabbits/group) for SC injection of 0.05, 0.1, and 0.2 mL of a CSFV subunit E2 vaccine (representing 1.15, 2.3, or 4.6 μg of E2 protein/dose, respectively) or saline (0.9% NaCl) solution. Blood samples were collected 21 days after vaccination for measurement of the antibody response against CSFV via ELISA and virus neutralization methods. On the same day, the CSFV Chinese (C) strain was injected into an ear vein. Vaccine efficacy was determined by monitoring of rabbits for pyrexia for 4 days and measurement of viral copies in spleen lysates at the end of the study. Reproducibility of the antibody response was tested with 2 other batches of the vaccine at the minimum immunization dose identified for the initially tested batch.

RESULTS
The E2 protein dose of the initially tested vaccine was positively correlated with the antibody response and protection rate in rabbits. The identified minimum immunization dose per rabbit was 0.1 mL, representing an E2 protein content of approximately 2.3 μg, and reproducibility of the antibody response to vaccination with the 2 other batches at this dose was good.

CONCLUSIONS AND CLINICAL RELEVANCE
A method was established in rabbits for evaluation of the efficacy of a CSFV subunit vaccine that could help in the optimization of later large-scale vaccine production and quality control processes as well as in the clinical application of the vaccine.
Gift-exchange Game Theory for Gamification on Digital Data Collection Systems
Authors: Supriyanto Supriyanto , Fahana Jefree 
Published: May 2020

Gamification is widely used to increase user motivation by applying game elements to things that are not game-based. For example, in a data collection system. Gamification is used to increase the motivation of users to want to get involved. The elements of the game that are often used are rewards, badges, and leaderboards. But some implementations have not been able to ensure increased user motivation. Gamification applied needs to consider the use of game theory. Game theory is used to determine the right gamification model for digital data collection. This paper discusses the application of gift-exchange-games (GEG) in the gamification of digital data collection systems. GEG is used to model player interactions in the gamification system. GEG implementation of Gamification can improve user involvement in the system. This theoretical model can later be used for a more efficient data collection system development platform.
Keywords: gamification, game theory, data collection, gift-exchange-game, geg
KAJI BANDING PENINGKATAN PRODUKSI TERNAK BABI DI PROVINSI BALI MENGGUNAKAN TEKNOLOGI INSEMINASI BUATAN DAN KAWIN ALAM
Authors: N. L. G. Sumardani , Budaarsa K. , Putri T. I. , Puger A. W. 
Published: May 2020

Penelitian ini bertujuan untuk mengetahui perbandingan antara teknologi inseminasi buatan dengan kawinalam dalam peningkatan produksi ternak babi di Provinsi Bali. Data yang digunakan berupa sampel, diambilberdasarkan lokasi, waktu, biaya, dan sumber daya manusia. Teknik pengambilan sampel menggunakan teknik purposive random sampling. Variabel yang diamati meliputi: sistem perkawinan, litter size (LZ), calving rate (CR), dan service per conception (S/C). Hasil yang diperoleh adalah teknologi inseminasi buatan (51,56±9,43) lebih sering diaplikasikan (P>0,05) dibandingkan dengan kawin alam (42,33±8,88). Namun demikian hasil pengawinan dari kedua metode tersebut tidak berbeda nyata (P<0,05). Berturut-turut hasil dari teknologi IB dan kawin alam pada litter size adalah 8,76±0,57 dan 8,83±0,63 ekor; calving rate sebesar 99,40±1,40% dan 100±0%; dan service per conception 1,00±0,02 dan 1,00±0 . Disimpulkan bahwa hasil pengawinan secara inseminasi buatan yang meliputi litter size, calving rate dan service per conception, tidak berbeda nyata dengan pengawinan secara alami. Efisiensi pejantan, pengawinan dengan inseminasi buatan lebih efektif dan efisien dibandingkan dengan kawin alam.
TRANSFORMASI GEN ALBUMIN BUNGA MATAHARI (Helianthus annuuss L.) DENGAN VEKTOR Agrobacterium tumefaciens SECARA IN PLANTA PADA TANAMAN KEDELAI
Authors: I. W. Suberata 
Published: May 2020

Penggunaan A. tumefaciens untuk maksud mengintroduksi DNA albumin bunga matahari ke dalam sel tanaman kedelai didasari atas kemampuan alami dari A.tumefaciens untuk mentransfer suatu fragmen yang spesifik dari DNA plasmid (T-DNA ) ke dalam sel tanaman lalu berintegrasi pada genom sel tanaman inang. Hasil kloning gen albumin yang ditumbuhkan pada bakteri E.coli selanjutnya ditransfer ke A. tumefaciens LBA4404, melalui metode triparental mating. A. tumefaciens LBA4404 (pAL4404, pSW600 ) yang dihasilkan kemudian ditransformasikan pada tanaman kedelai secara in planta. Hasil analisis transformasi pada tanaman kedelai transgenic secara in planta dapat dibuktikan dengan analisis PCR.
Pengaruh Senam Prolanis terhadap Perubahan Kadar Hemoglobin Sebelum dan Sesudah Senam di Klinik Cempaka Pulogebang Jakarta Timur
Authors: Nusantara Bangun Cholifa , Farhan Fanny Septiani 
Published: May 2020

Latar belakang: hemoglobin memiliki fungsi yaitu mentranspor oksigen. Latihan aerobik menyebabkan jaringan kekurangan oksigen. Hipoksia jaringan akan merangsang ginjal mengeluarkan hormon eritropoetin. Eritropoetin merangsang pematangan eritrosit dalam sumsum tulang. Sehingga akan menyebabkan peningkatan hemoglobin. senam Prolanis (Program Pengelolaan Penyakit Kronis) merupakan latihan jasmani aerobik yang merupakan salah satu program pemerintah. Penelitian ini ingin mengetahui pengaruh senam prolanis terhadap kadar hemoglobin sebelum dan sesudah senam. Metode: metode yang digunakan adalah kuasi eksperimen yang pembuktiannya diperoleh melalui perbandingan kondisi subjek sebelum perlakuan dengan sesudah diberi pelakuan dengan jumlah 16 responden. Dalam penelitian ini, jumlah sampel didapatkan dengan cara total sampling. Kadar Hemoglobin diukur dengan Point of Care Test (POCT). Hasil: pada penelitian ini hasil uji statistik telah didapatkan nilai p 0.276 yang berarti p>0.05 di mana didapatkan hasil yang tidak bemakna antara senam prolanis dengan perubahan kadar hemoglobin. Kesimpulan: didapatkan hasil bahwa tidak terdapat pengaruh antara senam prolanis dengan kadar hemoglobin. Karena dapat disebabkan beberapa faktor seperti ketidak efektifan senam, yang disebabkan waktu senam tidak mencapai nilai zona latihan pada penelitian ini.
Bonde universitário: ações de prevenção das infecções sexualmente transmissíveis: um relato de experiência
Authors: De Almeida Lilian Conceição Guimarães , Santos Jamile Mendes da Silva , Da Silva Yone Cardeal , Mascarenhas Rebeca Nascimento dos Santos , Dos Santos Maiara Oliveira , Do Nascimento Daine Ferreira Brazil , Brasil Bruna Prates Lopes 
Published: May 2020

Objetivo: Relatar a experiência de graduandas de enfermagem em ações extensionistas de prevenção das Infecções Sexualmente Transmissíveis (IST). Relato de experiência: O projeto é composto por graduandas de enfermagem da Universidade Federal da Bahia. Para subsidiar as ações realizadas houve a formação teórico/prática, na qual eram realizadas discussões semanais fomentando uma maior aproximação da equipe executora com a temática. As ações extensionistas foram fundamentadas a partir de metodologias ativas e realizadas nos mais distintos espaços entre ruas, escolas e campi da universidade. Durante as abordagens foram disponibilizados materiais educativos sobre IST, insumos de prevenção como preservativos e gel lubrificante, além da realização de testagem para HIV. As capacitações que antecederam as atividades oportunizaram a ampliação dos conhecimentos e trocas de experiências significativas. Foi possível identificar que muitas pessoas adotam comportamentos de invulnerabilidade. Em contrapartida, também houve devolutivas positivas como expressões de interesse, curiosidade e relatos de vivências sobre o assunto. As ações de prevenção extramuros implementadas foram percebidas como um importante mecanismo de enfrentamento das IST. Considerações finais: Falar sobre IST ainda é um tabu na sociedade. Atividades extensionistas, são fundamentais para o fortalecimento do vínculo entre academia e comunidade.
The use of progesterone during pregnancy in women with epilepsy as an alternative to the correction of doses of anticonvulsants
Authors: Tsallagova Elena V. , Generalov Vasily O. , Sadykov Timur R. 
Published: May 2020

Pregnancy is the most dangerous period in terms of interruption of even persistent and long-term remission. At the same time increasing the dose of anticonvulsant increases the risk of teratogenic effects.
Aim. to assess the possibility of using progesterone to prevent relapse of epileptic seizures during pregnancy.
Materials and methods. 38 pregnant patients with epilepsy with clinical remission before pregnancy, with relapse of epileptic seizures in I trimester of pregnancy, age 31.81.4 years. Dydrogesterone in a dose of 10 to 60 mg/day was prescribed after the relapse of remission. Anticonvulsant dosage was not changed. The blood progesterone concentration and EEG control was carried out.
Results. During pregnancy, the level of progesterone in the blood gradually increased from 77.8 nmol/l at 78 weeks of pregnancy to 521.1 nmol/l at 3637 weeks of pregnancy, without exceeding the limits. EEG results did not deteriorate. None of the patients had seizures during pregnancy.
Conclusion. Progesterone therapy is an adequate and safe alternative to increasing the dose of anticonvulsants in case of recurrent seizures during pregnancy.
Analysis of efficiency of application of media with hyaluronic acid in cryoprotocols
Authors: Protopopova Natalia V. , Druzhinina Elena B. , Krylova Kseniia V. , Mylnikova Iuliia V. , Dvoryanov Jan A. , Labygina Albina V. , Kovalenko Inna I. 
Published: May 2020

According to the World Health Organization, about 2 million new couples experience infertility annually, and their number is growing. An effective way to overcome infertility is assisted reproductive technology (ART). Cryopreservation will rationally solve the issue of preservation and further use of embryos: to delay pregnancy for some time considering womans desire and to prevent ovarian hyperstimulation syndrome. Embryo freezing allows to reduce the rate of repeated ovarian stimulation and perform preimplantation genetic diagnosis. Over the past decades, various cryotransfer options have been proposed to increase ART treatment efficacy, including the use of a culture medium with a high concentration of hyaluronic acid, but there are conflicting data on the use of such a medium in ART programs.
Aim. Evaluation of thawed embryo transfers efficacy using the hyaluronic acid-containing culture medium. To achieve the goal, the following tasks were set: to evaluate clinical and medical history data of patients with tubal infertility in cryoprotocols, to analyze the previous cycle of in vitro fertilization and embryological stage, to evaluate the effectiveness of the culture medium with a high content of hyaluronic acid.
Materials and methods. A detailed description of the patient sample, inclusion and exclusion criteria, embryological stage, embryo grading, devitrified embryo transfer technique. The article includes 3 tables which present the groups general clinical characteristics, the embryological stage, the rate of pregnancy, depending on the cultivation day.
Results. The authors established that in patients with a history of pelvic surgery and sexually transmitted infections, it is advisable to use the culture medium with a high content of hyaluronic acid to transfer the thawed embryo. It was shown that pregnancy rate is 1.5 times higher when transferring devitrified embryos on the 5th day of development with the use of hyaluronic acid-containing culture medium.
The conclusion about the pregnancy rate in obese patients is not indisputable, which requires further study. The authors also provide practical recommendations on the use of the culture medium with hyaluronic acid in cryoprotocols.
Conclusion. The study allows to optimize the devitrified embryo transfer in patients with tubal infertility using a culture medium with a high content of hyaluronan. This work has undoubted scientific and practical significance.