bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermodynamics of DNA: heat capacity changes on duplex unfolding
Authors: Dragan Anatoliy , Privalov Peter , Crane-Robinson Colyn 
Published: November 2019

Abstract
The heat capacity change, ΔCp, accompanying the folding/unfolding of macromolecules reflects their changing state of hydration. Thermal denaturation of the DNA duplex is characterized by an increase in ΔCp but of much lower magnitude than observed for proteins. To understand this difference, the changes in solvent accessible surface area (ΔASA) have been determined for unfolding the B-form DNA duplex into disordered single strands. These showed that the polar component represents ~ 55% of the total increase in ASA, in contrast to globular proteins of similar molecular weight for which the polar component is only about 1/3rd of the total. As the exposure of polar surface results in a decrease of ΔCp, this explains the much reduced heat capacity increase observed for DNA and emphasizes the enhanced role of polar interactions in maintaining duplex structure. Appreciation of a non-zero ΔCp for DNA has important consequences for the calculation of duplex melting temperatures (Tm). A modified approach to Tm prediction is required and comparison is made of current methods with an alternative protocol.
Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system
Authors: Schöneich Stefan , Hedwig Berthold 
Published: November 2019

AbstractWe investigated the central nervous coordination between singing motor activity and abdominal ventilatory pumping in crickets. Fictive singing, with sensory feedback removed, was elicited by eserine-microinjection into the brain, and the motor activity underlying singing and abdominal ventilation was recorded with extracellular electrodes. During singing, expiratory abdominal muscle activity is tightly phase coupled to the chirping pattern. Occasional temporary desynchronization of the two motor patterns indicate discrete central pattern generator (CPG) networks that can operate independently. Intracellular recordings revealed a sub-threshold depolarization in phase with the ventilatory cycle in a singing-CPG interneuron, and in a ventilation-CPG interneuron an excitatory input in phase with each syllable of the chirps. Inhibitory synaptic inputs coupled to the syllables of the singing motor pattern were present in another ventilatory interneuron, which is not part of the ventilation-CPG. Our recordings suggest that the two centrally generated motor patterns are coordinated by reciprocal feedforward discharges from the singing-CPG to the ventilation-CPG and vice versa. Consequently, expiratory contraction of the abdomen usually occurs in phase with the chirps and ventilation accelerates during singing due to entrainment by the faster chirp cycle.
INDISIM-Denitrification, an individual-based model for study the denitrification process
Authors: Araujo-Granda Pablo , Gras Anna , Ginovart Marta , Moulton Vincent 
Published: November 2019

Abstract
Denitrification is one of the key processes of the global nitrogen (N) cycle driven by bacteria. It has been widely known for more than 100 years as a process by which the biogeochemical N-cycle is balanced. To study this process, we develop an individual-based model called INDISIM-Denitrification. The model embeds a thermodynamic model for bacterial yield prediction inside the individual-based model INDISIM and is designed to simulate in aerobic and anaerobic conditions the cell growth kinetics of denitrifying bacteria. INDISIM-Denitrification simulates a bioreactor that contains a culture medium with succinate as a carbon source, ammonium as nitrogen source and various electron acceptors. To implement INDISIM-Denitrification, the individual-based model INDISIM was used to give sub-models for nutrient uptake, stirring and reproduction cycle. Using a thermodynamic approach, the denitrification pathway, cellular maintenance and individual mass degradation were modeled using microbial metabolic reactions. These equations are the basis of the sub-models for metabolic maintenance, individual mass synthesis and reducing internal cytotoxic products. The model was implemented in the open-access platform NetLogo. INDISIM-Denitrification is validated using a set of experimental data of two denitrifying bacteria in two different experimental conditions. This provides an interactive tool to study the denitrification process carried out by any denitrifying bacterium since INDISIM-Denitrification allows changes in the microbial empirical formula and in the energy-transfer-efficiency used to represent the metabolic pathways involved in the denitrification process. The simulator can be obtained from the authors on request.
Fuel Subsidies Versus Market Power: Is There a Countervailing Second-Best Optimum?
Authors: Adetutu Morakinyo O. , Weyman-Jones Thomas G. 
Published: November 2019

Abstract
Fuel subsidies distort end-use prices below cost, resulting in overconsumption and huge environmental cost. On the other hand, the mark-up over cost due to the exercise of market power results in the social loss of consumer surplus. We open a new line of inquiry into the potential for a market-based solution from these two countervailing forces: can the two offsetting distortions conceivably achieve a second- best optimum? Relying on dynamic panel techniques and gasoline market data for 68 developing countries, we uncover an excessive second-best subsidy offset to market power mark-up on the order of 4.5. Our results indicate that the potential for policy failure strongly exceeds the potential for market failure in our model, and gasoline prices across our sample may not be aligned with vigorous anti-climate change policy.
On the other end of research: exploring community-level knowledge exchanges in small-scale fisheries in Zanzibar
Authors: Hakkarainen Viola , Daw Tim M. , Tengö Maria 
Published: November 2019

Abstract
Sustainability science has increasingly adopted more action-oriented approaches in an attempt to mobilise and implement a broad knowledge base to sustain human wellbeing and promote sustainable development. There is an increasing recognition of the importance of knowledge exchange (KE) between scientists and end users of research for enhancing social, environmental and economic impacts of research. Here, we explore the process of KE through close observation of two cases of KE between external PhD researchers and local actors in small-scale fisheries at the community level in Zanzibar, Tanzania. First, we address context by examining perceptions of research held by actors at community level and patterns of interactions and flows of benefits between external researchers and local actors including fisheries managers, local research institute as well as fishers and traders. Second, we unpack experiences of actors engaged in the cases of KE. The study draws attention to KE processes in the Global South and actors outside decision-making processes in fisheries management. The study concludes that as KE is a complex and dynamic process and that (i) history and relationships between actors shape the outcomes of KE, (ii) KE includes more than knowledge-based processes and outcomes because multiple incentives of different actors shape KE and how it is experiences and (iii) knowledge-based outcomes of KE are complex and unpredictable as different actors create their own meaning from shared information. The results exemplify the inevitably complex and unpredictable nature of KE processes and their outcomes, and provide insight into how KE can contribute to science–society relationships.
NMR resonance assignments of the four isoforms of the hazelnut allergen Cor a 1.04
Authors: Führer Sebastian , Zeindl Ricarda , Tollinger Martin 
Published: November 2019

Abstract
In large parts of Europe, Northern America and China people are suffering from allergies after consuming certain kinds of fruits and vegetables. Typical allergic symptoms range from scratching and itching of the throat to severe symptoms like rhino conjunctivitis and anaphylaxis. For hazelnuts (Corylus avellana), these allergies result from initial sensitization to the birch (Betula verrucosa) pollen allergen Bet v 1 and subsequent development of allergic cross-reactions to proteins that are similar in their three-dimensional structure to the sensitizing protein Bet v 1. The cross-reactive proteins in hazelnut are the four isoforms Cor a 1.04 with a molecular weight of about 17.5 kDa. Significant differences regarding the immunologic behavior of these proteins have been reported. In this work we assigned backbone and side chain 1H, 13C, and 15N chemical shifts of these four isoforms, Cor a 1.0401, Cor a 1.0402, Cor a 1.0403, and Cor a 1.0404 by solution NMR spectroscopy. The chemical shift data confirm the characteristic Bet v onefold for all four isoforms, consisting of seven β-strands that are separated by two short α-helices, along with a long C-terminal α-helix. These data provide the basis for a comparative structural and dynamic analysis of these proteins by NMR in order to characterize their different immunologic cross-reactivities on a molecular level.
Human–Robot Collaboration Acceptance Model: Development and Comparison for Germany, Japan, China and the USA
Authors: Bröhl Christina , Nelles Jochen , Brandl Christopher , Mertens Alexander , Nitsch Verena 
Published: November 2019

Abstract
The use of robots in the national economy—especially in industrialized countries—is growing. At the same time, the interdependency between humans and robots is getting increasingly closer: they are engaging in direct contact with each other as more and more organizations let robots and humans work hand-in-hand. One factor that predicts successful human–robot interdependency is the acceptance of the robot by the human. Generally, only when an innovative assistive working system covers human needs and expectations, it is perceived to be useful and hence accepted. Furthermore, it has been found that cultural context has an impact on human–robot interaction, as people feel more comfortable interacting with a robot in a culturally normative way. Therefore this paper aims at presenting a human–robot collaboration acceptance model (HRCAM) with regard to the collaboration between humans and robots that is based on prior acceptance models, while also considering technology affinity and ethical, legal and social implications. Additionally, similarities and differences in robot acceptance are shown for four selected countries—both in comparison to the overall human–robot collaboration acceptance model and between the countries. The HRCAM additionally shows which variables influence perceived usefulness and perceived ease of use, and thus behavioral intention to use and use behavior. A further distinction is made between anchor variables, which can be influenced in the long term, and adjustment variables, which can be influenced in the short to medium term. The model therefore offers practitioners in the field of human–robot collaboration recommendations to increase the acceptance of robots.
Methods of crop yield measurement on multi-cropped plots: Examples from Tanzania
Authors: Wineman Ayala , Anderson C. Leigh , Reynolds Travis W. , Biscaye Pierre 
Published: November 2019

Abstract
Precise agricultural statistics are necessary to track productivity and design sound agricultural policies. Yet, in settings where multi-cropping is prevalent, even crop yield—perhaps the most common productivity metric—can be challenging to measure. In a survey of the literature on crop yield in low-income settings, we find that scholars specify how they estimate the area denominator used to measure yield in under 10% of cases. Using household survey data from Tanzania, we consider four alternative methods of allocating land area on multi-cropped plots, ranging from treatment of the entire plot as the yield denominator to increasingly precise approaches that account for the space taken up by other crops. We then explore the implications of this measurement decision for analyses of yield, focusing on one staple crop that is often grown on its own (rice) and one that is frequently found on mixed plots and in intercropped arrangements (maize). A majority (64%) of cultivated plots contain more than one crop, and average yield estimates vary with different methods of calculating area planted—particularly for maize. Importantly, the choice among area methods influences which of these two crops is found to be more calorie-productive per hectare. This choice also influences the statistically significant correlates of crop yield, such that the benefits of intercropping and including legumes on a maize plot are only evident when using an area measure that accounts for mixed cropping arrangements. We conclude that the literature would benefit from greater clarity regarding how yield is measured across studies.
Single-phase friction riveting: metallic rivet deformation, temperature evolution, and joint mechanical performance
Authors: Pina Cipriano Gonçalo , Ahiya Aakash , dos Santos Jorge F. , Vilaça Pedro , Amancio-Filho Sergio T. 
Published: November 2019

Abstract
The present work explores the feasibility of single-phase friction riveting on unreinforced thermoplastics. In single phase, the load is kept constant throughout the process, avoiding the forging phase with higher axial force, used in the conventional process. This process variant can constitute an answer when payload restrictions exist. The results demonstrate the feasibility of single-phase friction riveting on unreinforced polyetherimide plates joined by AA2024 rivets with 5 mm of diameter. A Box-Behnken design of experiments and analysis of variance were used to set parameter matrix and understand the correlations between parameters and joint properties. A large variation of the mechanical energy input was observed (151–529 J). Over-deformation and material rupture were observed in higher energy conditions. Lower energy input yielded a bell-shaped rivet plastic deformation, corresponding to the best performance. The maximum process temperatures varied between 461 and 509 °C. This friction riveting process variant allowed a considerable high mechanical strength to be achieved, with ultimate tensile force of 7486 N, comparable with the two-phase friction riveting process, albeit applying lower axial forces, such as 2400 N. Within the investigated conditions, this study proves the feasibility of the single-phase process, achieving good global mechanical performance and energetically efficient conditions, without forging phase.
Ethics education should make room for emotions: a qualitative study of medical ethics teaching in Indonesia and the Netherlands
Authors: Muhaimin Amalia , Hoogsteyns Maartje , Utarini Adi , Willems Derk Ludolf 
Published: November 2019

Abstract
Studies have shown that students may feel emotional discomfort when they are asked to identify ethical problems which they have encountered during their training. Teachers in medical ethics, however, more often focus on the cognitive and rational ethical aspects and not much on students’ emotions. The purpose of this qualitative study was to explore students’ feelings and emotions when dealing with ethical problems during their clinical training and explore differences between two countries: Indonesia and the Netherlands. We observed a total of eighteen ethics group discussions and interviewed fifteen medical students at two medical schools. Data were interpreted and analyzed using content analysis. We categorized students’ negative emotions based on their objects of reflection and came up with three categories: emotions concerning their own performance, emotions when witnessing unethical behaviors, and emotions related to barriers and limitations of their working environment. Our study suggests that addressing emotional responses in a culturally sensitive way is important to develop students’ self-awareness. Teachers should be able to guide students to reflect on and be critical of their own thoughts and emotions, to understand their own moral values, especially when confronted with other individuals.
No-Platforming and Higher-Order Evidence, or Anti-Anti-No-Platforming
Authors: LEVY NEIL 
Published: November 2019

AbstractNo-platforming—the refusal to allow those who espouse views seen as inflammatory the opportunity to speak in certain forums—is very controversial. Proponents typically cite the possibility of harms to disadvantaged groups and, sometimes, epistemically paternalistic considerations. Opponents invoke the value of free speech and respect for intellectual autonomy in favor of more open speech, arguing that the harms that might arise from bad speech are best addressed by rebuttal, not silencing. In this article, I argue that there is a powerful consideration in favor of no-platforming some speakers: allowing them a platform generates genuine higher-order evidence in favor of their claims. When that higher-order evidence would be misleading, we may reasonably believe it should not be generated.
Radiocarbon age offsets of Plants and Shells in Holocene sediments from the Sukumo plain, Southwest Coast of Shikoku, Southwest Japan
Authors: Nakanishi Toshimichi , Tsuji Tomohiro , Nanayama Futoshi , Yamaguchi Tatsuhiko , Kondo Yasuo , Ikeda Michiharu , Hong Wan 
Published: November 2019

AbstractTo identify chronological changes in the marine reservoir effect in southwest Japan, the radiocarbon ages of eight pairs of marine shells and terrestrial plants were measured from the same horizons of one core of Holocene sediments. This core was obtained from the northern part of the Sukumo Plain in southwestern Shikoku Island, which faces the warm Kuroshio Current. The drilling site is located in an area of subsidence associated with the convergence of the Philippine Sea Plate and the Eurasian Plate. On analyses of lithology, molluscan assemblages, and radiocarbon dating, we interpreted, from oldest to youngest, nine units: basement rock, a braided river channel, a meandering river channel, an estuary, a transgressive inner bay, Kikai-Akahoya volcanic ash, a deltaic inner bay, a tidal flat, and artificial soil. Changes in the depositional environment were mainly associated with sea-level rise after the end of the last glaciation. The reservoir ages of the eight pairs, 330 ± 70 yr, were obtained from a transgressive inner bay to deltaic inner bay sediments, formed during 4100–9200 cal BP. The chronological change in the reservoir effect allows us to correlate the Sukumo Core sediments with previous results from southwestern Japan, the Korean Peninsula, and Taiwan Island.
Financing China's engagement in Africa: new state spaces along a variegated landscape
Authors: Siu Helen F. 
Published: November 2019

AbstractRecent studies on Chinese investment in Africa have particularly focused on the hardware of development – infrastructure – and its impact. China's vision to forge a new global order was made explicit when Xi declared his ‘One Belt, One Road’ policy in 2013. Underlying the grand infrastructural schemes and political posturing are hidden financial manoeuvres, the soft side of power, unspoken sociality and value contestations. This article focuses on the variegated landscape of China–Africa trade/finance infrastructure centring on Hong Kong. It highlights top-down state orchestration but also explores historical contingencies that have shaped the strategies of those whose footprints unexpectedly straddle continental divides.
The need to travel: Malian women shuttle traders, autonomy and (mis)trust in neoliberal Dakar
Authors: Jónsson Gunvor 
Published: November 2019

AbstractRecent infrastructural developments in Senegal have severely impacted on the livelihoods of femalebana-banasfrom Mali, a group of mobile traders operating in the Mali–Dakar corridor: transportation costs have significantly increased, travelling has become a more exhausting experience, and fatal accidents have become more frequent during journeys. Why did thebana-banascontinue these arduous journeys? Why was their physical presence required in Dakar, and why did they not rely more extensively on social networks to facilitate their transnational trade? This article examines the conditions of autonomy, flexibility and limited trust that characterized thebana-banas’ livelihoods and necessitated their continued mobility from Mali. The recent infrastructural transformations have led to an increased commercialization and disarticulation of Malian trade networks in the Senegalese capital, and, due to personal circumstances, the women have often been cut off from networks. However, unlike general expectations of the ways in which networks evolve under conditions of neoliberalism, thebana-banashave not turned to personalized relationships of trust in Dakar, which might have facilitated their trade from a distance. The article contributes to the growing literature on social networks and trust by exploring how transnational trade does and does not work at this historical moment and in the context of gendered constraints.
An Argument for the Continued Validity of Woman-to-Woman Marriages in Post-2010 Kenya
Authors: Kareithi Monicah , Viljoen Frans 
Published: November 2019

AbstractWoman-to-woman marriage is a form of customary marriage between two women, predominantly found in Africa. These customary marriages have been and to some extent still are conducted by various communities across Africa, including in Kenya. Communities such as the Kamba, Kisii, Nandi, Kikuyu and Kuria practise woman-to-woman marriages for a variety of reasons. The legal status of woman-to-woman marriages in Kenya is uncertain due to the provisions of article 45(2) of Kenya's Constitution of 2010 and section 3(1) of the Marriage Act of 2014, which stipulate that adults only have the right to marry persons of the opposite sex. However, a holistic and purposive reading of the constitution, taking into consideration its recognition of culture and the protection of children as important values in Kenyan society, and considering the historical context within which the provisions concerning same-sex marriages were included, leads to the conclusion that these provisions were not intended to proscribe the cultural practice of woman-to-woman marriage in Kenya. The constitutional validity of woman-to-woman marriage opens the door to a more expansive and fluid understanding of “family” in Kenya.