bluuebunny/crossref_metadata_2025_split huggingface dataset:
ENSINO DE FÍSICA E TECNOLOGIA ASSISTIVA: UM NOVO OLHAR PARA A INCLUSÃO
Authors: Silvestre Moura da Silva Lílian , Costa Cruz Mariana , Gosson Gadelhas de Freitas Fortes Vanessa 
Published: October 2020

Na época atual, a demanda de alunos com necessidades especiais vem crescendo exponencialmente a cada ano, e com isso o índice de apoio nas escolas também se torna bastante necessário. Por meio dessa pesquisa, o objetivo é evidenciar o uso da tecnologia assistiva, integrando o papel da monitoria, ajuda no desenvolvimento mais crucial para os discentes dentro e fora de sala de aula, já que sem essa beneficência, o aluno não consegue incluir-se de maneira significativa no âmbito escolar em uma sala de aula de ensino regular comum. Então, para alcançar esse propósito, a metodologia possui um cunho qualitativo de modo de pesquisa ação, que permeia entre a adaptação de atividades, junto a tecnologia de softwares, e materiais acessíveis feitos com utensílios, no qual muitas vezes são de baixo custo, que acabam se tornando um grande auxílio durante o ano letivo do discente, e por sua vez, para o professor que não consegue ministrar e incluir o aluno, na aula com os recursos utilizados atualmente, por não ter o vasto conhecimento sobre a área, com efeito, o aluno com Necessidades Educacionais Específicas (NEE) não compreende o conteúdo. Visto que, historicamente o processo de inclusão na educação regular é tema de várias discussões advindas de uma trajetória de exclusão longa, de tal forma que, nesse processo de inclusão, surge a tecnologia assistiva como uma grande aliada para o interesse do aluno com NEE aprender o conteúdo proposto. Os resultados de utilizar diversas tecnologias assistivas proporciona, concomitantemente, essa formação inicial aos alunos de licenciatura em física, no qual durante todo o período da graduação não são capacitados a receber um aluno com tais características, e possibilitar tanto aos discentes um atendimento mais específico que pretende minimizar as suas dificuldades, e também, por consequência auxiliar na formação dos licenciandos – ou também chamados tutores/monitores – um vasto conhecimento de como exercer a sua docência a todos que necessitam. Por fim, é necessário expor a comunidade acadêmica que a tecnologia assistiva é uma estratégia para o ensino de física e um meio de proporcionar a efetiva inclusão.
TEOREMA DE PITÁGORAS: UMA INTERVENÇÃO PEDAGÓGICA EM UMA ESCOLA PÚBLICA DO MUNICÍPIO DE URUÇUÍ-PI
Authors: Martins Silva Lucas , Araújo de Oliveira Jaysla , Ribeiro Dias Jéssica , Rodrigues dos Santos Karol , Antônio Rodrigues Miguel 
Published: October 2020

Conforme a tradição pitagórica o número é o princípio de tudo, pois foi pelo estudo da aritmética e da geometria que os pitagóricos começaram a averiguar que determinados fenômenos poderiam ser comprovados através de termos numéricos ou quantitativos. Como exemplo desses fenômenos tem-se os ciclos da natureza, que se perpetuam, seja através da beleza numérica do girassol representado pela sequência de Fibonacci, ou os grandes padrões matemáticos que a própria natureza possibilita o ser humano presenciar constantemente. Nesse sentido, o teorema de Pitágoras atribui-se mediante seu valor significativo no ensino básico da matemática, além de contribuir em diversas situações-problema no cotidiano do ser humano. Este estudo teve como objetivo principal analisar como os estudantes do 9ª ano do Ensino Fundamental construíram a perspectiva do que seja o Teorema de Pitágoras de forma que atribuíssem significados ao objeto matemático aprendido. A pesquisa foi realizada em novembro de 2018 na Unidade Escolar Arica Leal, localizada no município de Uruçuí-PI. Em um primeiro momento, aplicou-se pré-teste para analisar o nível de aprendizagem dos discentes acerca do Teorema. Em seguida, foram realizadas atividades lúdicas para que os mesmos pudessem confirmar a aplicabilidade e a veracidade por meio de material concreto (perigal, cordas, fita métrica e pequenos pedaços colorido de madeira). Além disso, realizou-se a corrida pitagórica com o uso do aplicativo (Dice 3D Free) disponível na Play Store. E, por fim, executou-se o pós-teste, juntamente com coleta de dados para averiguar o nível de conhecimento adquirido ao longo das atividades realizadas. Os resultados mostraram entusiasmo e evolução dos alunos em participarem ativamente do processo de construção do conhecimento com o uso de metodologias dinâmicas que favorecem a aprendizagem. Dessa forma, o ensino de matemática com ajuda de metodologias, demonstrações, dentre outras que envolva a prática, torna a aprendizagem mais significativa e atraente.
Basic principles of ultrasound-assisted choice of strategy for targeted infusion therapy
Authors: Valenko O.O. , Akopiane H.V. 
Published: October 2020

Objective. Optimization of fluid therapy in emergency medicine.
Materials and methods: 1) conceptual four-phase liquid resuscitation model; 2) conceptual approach of infusion therapy management is based on an assessment of the four main components of haemocirculation: a vascular content, tone and integrity, blood flow; 3) fast bedside ultrasound algorithm for differential diagnosis of shocks and infusion resuscitation protocol using ultrasound of the inferior vena cava (preload assessment) and lungs (early detection of extravascular fluid).
Results. Using the selected methods, it is possible to clearly determine the optimal target-oriented infusion strategy depending on the volemic status and the state of hemodynamics, the parameters of which can be estimated using ultrasound: vascular content – inferior vena cava (caliber and breathing variations); vascular tone – caliber of the tibia artery; vascular integrity – loss assessment in the third space (physiological cavities and interstitium of the lungs); blood flow – Doppler Echo.
Conclusions. The use of diagnostic ultrasound allows to optimize tissue perfusion, keeping the intravascular fluid volume in a certain range by sorting patients into three categories of fluid management: infusion resuscitation, tested infusion, limiting infusion and early use of vasopressors, which reduces the number of adverse effects and the incidence of complications.
Modern approaches to treatment of superficial dermal burns
Authors: Kovalenko O.M. , Kovalenko A.O. , Оsadcha O.I. , Lynnyk O.M. 
Published: October 2020

Objective. The aim of the study is improving the treatment’s effectiveness in patients with superficial dermal burns due to the usage of modern wound dressings.
Materials and methods. Under observation were 150 patients with superficial dermal thermal lesions with an area of 5-30 % of the body surface aged 10-64 years, who were treated at the Kyiv City Clinical Hospital № 2 during 2016-2019. The main group consisted of 120 patients, whose burn’s treatment provided under wound dressings in a humid environment (hydrogel, spongy polyurethane foam, film coatings). Comparison group – 30 patients whose wounds were treated by applying wet-drying bandages or bandages with water-soluble antibacterial ointments.
Results and discussion. At the beginning of the treatment, the pH of the wound content of dermal burns was 7.9-8.1. On the 3rd day of treatment in patients of the main group, the pH of wounds under wound dressings was defined as acidic (5.7). In patients of the comparison group on the 3rd and 4th day the pH of the wounds was determined as alkaline, and only on the 6th day it became slightly acidic. As the pH of the wounds increased, the rate of healing decreased. In the phase of acute inflammation and exudation, the pH of superficial dermal burns was alkaline 7.8-8.2, in the proliferation phase, under the wound coverings – acidic (5.5-4.1). The use of wound dressings led to a decrease in the number of microbial association in patients to 1.1±0.4 on 9-11th days after injury, the colonization of wound surfaces changed slightly to 3×102 per 1 g. In contrast, in patients of the comparison group in the sequestration period of superficial necrotic scab increased the number of microbial associates to 2.8±0.7, wound colonization increased to 105 per 1 g of tissue. The time of epithelialization with the use of wound dressings was 13.8±1.7 days, in patients of another group – 19.4±2.5 days.
Conclusions. Wound dressings that keep the wound moist are an effective way to influence the wound process, which can be regulated. In the treatment of superficial dermal burns under wound dressings there is a change of the alkaline reaction to acidy, which stimulates wound healing. Wound management in a wet closed chamber changes the qualitative and quantitative composition of the wound microflora, reduces the microbial contamination of burn wounds by two orders of magnitude. Superficial dermal burns heal under wound dressings for 13.8 days against 19.4 in traditional treatment.
Morphological features of animal organs after introduction of new ALX-5 % protein-salt solution
Authors: Kondratskyi B.O. , Kachmaryk D.L. , Panas O.M. , Vynarchyk M.Y. , Braginets O.G. 
Published: October 2020

Objective. To investigate the morphological features of the internal organs of experimental animals and identify potential target organs with the introduction of ultra-high doses of the drug ALX-5 % and the drug with double the concentration of components ALX-2N.
Materials and methods. The experiments were performed on outbred white male mice and outbred white male rats. Animals were administered ALX-5 % and ALX-2N solution. ALX-5 % protein-saline solution contains: donor albumin (5 %) pentatomic alcohol xylitol (5 %), alkalizing components – sodium lactate (1.9 %) and sodium bicarbonate (0.01 %), as well as sodium chloride (0.8 %), potassium chloride (0.03 %), calcium chloride (0.01 %). Theoretical osmolarity – 990 mOsm/l, pH – 6.2-7.4. The drug with double the concentration of ALX-2N contains all these components in double the concentration (osmolarity of the solution – 1980 mOsm/l). ALX-5 % was administered intraperitoneally multiple times at a dose of 174 ml/kg for mice and 90 ml/kg for rats. These doses are conditionally toxic, as these doses are the maximum that animals have been able to administer. Further increase in the volume of infusion solution was not allowed due to possible excessive hypervolemic effect. The ALX-2N solution was administered at a dose of 50 ml/kg. At the end of the experiment, histological preparations were prepared from the internal organs of animals, which were stained with hematoxylin and eosin and toluidine blue and studied under a light microscope.
Results and discussion. It was found that when white mice and white rats were injected with the native protein-salt preparation ALX-5 % (osmolarity of the solution – 990 mOsm/l) in ultra-high doses (174 ml/kg for mice and 90 ml/kg for rats) the main target organs were the brain and lungs. Changes in other organs (kidneys, liver, pancreas, spleen, heart) are uncritical. With the introduction of concentrated drug ALX-2N (osmolarity of the solution – 1980 mOsm/l) at a dose of 50 ml/kg in addition to pronounced changes in the lungs and brain, dystrophic changes of heart and liver cells are observed. In all the study groups of animals accumulation of glycogen was observed, which is obviously due to administration of the high dose polyhydric alcohols xylitol and sodium lactate, a significant part of which is metabolized in the liver.
Conclusions. According to the results of a comprehensive study of pharmaco-toxicological properties, it was found that the multicomponent protein-salt solution ALX-5 % may be suitable for further clinical study.
Features of the composition of certain complex hyperosmolar infusion solutions
Authors: Kondratskyi B.O. , Kachmaryk D.L. , Panas O.M. , Vynarchyk M.Y. , Novak V.L. 
Published: October 2020

Objective. To justify the use of complex hyperosmolar solutions.
Results and discussion. Today, the question of the qualitative composition and quantitative relationship between the various components of infusion-transfusion therapy remains controversial. Hypertonic solutions in various concentrations of NaCl were first used for “low-volume resuscitation” in patients with hemorrhagic shock. Administration of these solutions results in a temporary osmotic pressure gradient between the blood plasma and the interstitial space, causing fluid to move into the intravascular space, increasing cardiac output, blood pressure, and improving microcirculation. Recently, combinations of hypertonic NaCl with colloids, as well as multicomponent infusion drugs are increasingly used. These are, in particular, the drugs Rheosorbilact, Xylate, Lactoxyl, Sorbilact, Lactoprotein with sorbitol, Gecoton developed at the Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine. Preparations based on polyhydric alcohols of sorbitol or xylitol, alkalizing agents of sodium lactate or sodium acetate and electrolytes. Rheosorbilact, Xylate, Lactoxyl are basic solutions for detoxification therapy, including in patients with diabetes. Sorbilact used as an osmodiuretic and for the treatment of patients in the postoperative period. Protein-salt solution based on donor albumin Lactoprotein with sorbitol is a mean for intensive care in emergencies. Colloid-hyperosmolar infusion solution Gecoton based on hydroxyethyl starch is used as a mean for low-volume resuscitation in the prehospital stage, including combat victims. Specially selected substances comprising the combined drugs affect different parts of the pathological process and have several advantages compared to mono-drugs. The pharmacological action of such solutions is due to the mutual potentiation of the action of its components. This provides hemodynamic effect and can reduce the dosage of each component separately, reducing the likelihood of side effects. The use of multicomponent hyperosmolar solutions can significantly reduce the total volume of fluid administered to patients.
Conclusions. Complete hyperosmolar drugs can be recommended for routine and auxiliary fluid therapy and treatment for emergency conditions.
The influence of myocardoprotection on the course of postinfarction chronic heart failure
Authors: Ruzieva A.A. 
Published: October 2020

Objective. To study the effect of Thiotriazoline in patients with post-infarction chronic heart failure (CHF).
Materials and methods. We examined 46 patients with ischemic heart disease (IHD) who had undergone myocardial infarction. The average age was 50.8±3.2 years; men – 32 (70 %), women – 14 (30 %). All patients were examined in the form of anamnesis and examination, general clinical and biochemical studies, electrocardiography. The assessment of CHF manifestations in patients of both groups was carried out according to the New York classification based on the results of the 6-minute walk test. The distribution into two groups was carried out according to the following parameters: the 1st group included 26 (56.5 %) patients (men – 19 [73.1 %], women – 7 [26.9 %]), who, along with basic therapy, received Thiotriazoline at a dose of 8.0 intravenously jet for 10 days; the 2nd (control) group included 22 (43.5 %) patients (men – 14 [63.6 %], women – 8 [36.4 %]) who received standard therapy (β-blockers, angiotensin-converting enzyme inhibitors, calcium antagonists, nitrates). Distribution by class of CHF at the time of inclusion in the study was observed in 1st group in 21 (80.7 %) patients: I functional class (FC) – 2 (9.5 %), II FC – 11 (52.4 %), III FC – 6 (28.6 %) and IV FC – 2 (9.5 %). In 2nd group – (77.3 %) patients: I FC – 3 (17.6 %), II FC – 6 (35.3 %), III FC – 7 (41.2 %) and IV FC – 1 (5.9 %) patients. According to the Minnesota questionnaire in group 1, the quality of life indicators (average value in points) were 71.1±1.8 points (p<0.05). The 2nd group had 67.9±1.9 points (p<0.05).
Results and discussion. Positive hemodynamics and assessment of CHF manifestations by FC served as a clear statement of improvement in the quality of life. In the group receiving Thiotriazoline, the number of patients with II FC increased from 11 (42.3 %) to 14 (54 %), I FC – from 2 (9.5 %) to 6 (23 %) compared to the initial data due to patients from III FC and IV FC. The number of patients with III FC decreased to 2 (7.8 %) and IV FC – to 1 (3.8 %), and in the control group there was a slight negative dynamic (III FC – to 2 (9.5 %) and IV FC – without changes). The quality of life according to the Minnesota questionnaire indicated a positive trend. In group 1, the quality of life indicators improved from 71.1±1.8 to 53.3±0.6 points (p<0.01); in group 2 – from 67.9±1.9 to 63.3±1.9 points (p<0.05).
Conclusions. Thiotriazoline is a cytoprotector of the highest class, in particular, a myocardoprotector, which, when used (from 10 days in a hospital and then up to 1 month), improves the metabolism of the heart muscle, stabilizing intracellular mechanisms. Thiotriazoline is indicated for all patients with IHD who have suffered a myocardial infarction in the early stages of CHF.
Positive experience of iron hydroxid saccharose complex intravenous infusions in III degree anemic puerperas treatment
Authors: Yaremchuk T.P. , Matsiura R.Ya. , Matsiura S.R. 
Published: October 2020

Objective. To improve the quality of severe anemic puerperas treatment on the ground of evaluation of the clinical efficacy of iron hydroxid saccharose complex intravenous infusions in the treatment of women with III degree hypochromic and posthemorrhagic anemias.
Materials and methods. The materials of research were 392 birth case reports of puerperas with III degree anemia, which gave birth in the Lviv Regional Perinatal Center in the first half of 2020. The methods of research were clinical, laboratory, ultrasound, instrumental, medical-statistical methods. Iron hydroxid saccharose complex infusions in a dose of 200 mg daily were performed in women once or twice with an interval of 2-3 days to receiving of Hb indicator >80 g/l, improving hematological indicators of anemia, disappearance of tachycardia, reducing other anemic syndrome manifestations. Women continued treatment with oral iron supplements under the female polyclinic supervision.
Results and discussion. Totally, 2,493 births and 806 cesarean sections were in Lviv Regional Clinical Perinatal Center, 9 cases of uterine bleedings were registered (0,27+0,09 % of all births) in the first half of 2020. In 0,15+0,07 % of cases obstetric bleedings developed due to uterine atony (0,2+0,09 % of parturitions). Intraoperative atonic obstetric bleedings developed in 0,12+0,06 % (0,5+0,25 % of cesarean sections). Anemias in the postpartum period were diagnosed in 392 puerperas, which formed 11,88+0,56 % of all births. Posthemorrhagic anemias accounted for 2,3+0,76 % of anemias, hypochromic anemias – 97,7+0,76 %. Iron hydroxid saccharose complex infusion was prescribed through one day after delivery. Adverse reactions were absent. Iron hydroxid saccharose complex application allowed to obtain clinical improvement in all cases within 5 days, increase Hb >80 g/l and improve anemia hematological indicators, speed up convalescence.
Conclusions. Iron hydroxid saccharose complex in the treatment of puerperas with III degree anemias (posthemorrhagic and hypochromic) have high clinical efficiency, well tolerated, reduce the hospital treatment duration.
Application of indirect electrochemical oxidation of blood in a complex of intensive therapy in children with urolithiasis complicated with chronic kidney disease
Authors: Ikromov T. , Abdulaliev A. 
Published: October 2020

Objective. To study the efficacy of sodium hypochlorite in children with urolithiasis complicated by chronic kidney disease (CKD).
Materials and methods. The results of the use of sodium hypochlorite 0.03-0.06 % in the pre- and postoperative period in 20 patients with urolithiasis complicated by stage IV CKD were analyzed. The indices of endogenous intoxication in venous cubital blood (VСK), mixed venous blood (MVB) flowing to the lungs and arterial blood (AB) flowing from the lungs were studied. Indirect electrochemical oxidation of blood (IEOB) was carried out in 20 patients with stage. For children under 12 years old, we used 0.03 %, and for the older age group from 12 to 18 years old ‒ 0.06 %, the volume of the injected solution did not exceed 1/10 of the patient’s CBV per infusion, at a rate of 40-60 drops/min. We have studied the use of sodium hypochloride (NaCIO) as a component of complex intensive care (CIC) in preoperative preparation in children with urolithiasis complicated by CKD and the effect of sodium hypochloride on detoxification lung function (DLF).
Results. There was a significant increase in low molecular weight toxic substances (creatinine, calurea), average mass molecules (AMM), lipid peroxidized products, oligopeptides of a high necrotic body mass (NB), circulating immune complex (CIC), integral indicators of toxicity leukocyte index of intoxication and index of intoxication, as well as a decrease in antioxidant protection, more pronounced at sub- and decompensated stages of DLF impairment in the examined group of patients before treatment in the basin of VKK, VCK and AB. In 7 (35.0 %) patients ‒ 1b compensated, in 13 (65.0 %) ‒ subcompensated stage of impairment.
Conclusions. CIC with the use of IEOB in the preoperative preparation by infusion of sodium hypochlorite in this subgroup of patients significantly improved DLF in relation to NB, CIC and high-weight oligopeptides. The use of NaCIO leads to inactivation of the entire spectrum of AMM and large toxic molecular compounds fixed on the membranes of blood corpuscles, and also, ensures the transformation of hydrophobic metabolites into hydrophilic ones, which are actively excreted by excretory organs.
The Nexus between Political Risks and Foreign Direct Investment: An Empirical Analysis for North African Countries
Authors: ÖZŞAHİN Cüneyt , ÖZŞAHİN Şerife 
Published: October 2020

Drawing from the ICRG data set, this study aims to analyze the intricate linkage
between political risks and foreign direct investment via a number of control variables
including trade openness, the consumer price index and per capita GDP. Since there has been
a paucity of research on certain determinants of FDI in the North African context, we
examine the impact of political risks on foreign direct investment inflows in six North African
countries covering the period 1996-2014 accounting for the presence of possible cross-
sectional dependence in the heterogeneous panel data. Whereas the results obtained from
Pedroni (1999) and Johansen-Fisher co-integration tests show that there is a long-run co-
integration relationship, coefficients obtained from the FM-OLS estimator indicate that a low
level of political risks has a positive impact on the foreign direct investment inflows, albeit
with some variation within select countries. The Canning and Pedroni (2008) causality test, on
the other hand, finds evidence that there is a causal relationship between political risks and
foreign direct investment for four countries (Algeria, Libya, Tunisia, and Egypt) in the
sample. Hence, the results suggest that political risks are significant determinants of foreign
direct investment for an array of countries in North Africa.