bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of the COVID-19 epidemic process in the Volga Federal District in 2020–2023
Authors: Tuzova I. N. , Sarskov S. A. , Kuzovatova E. E. , Polyanina A. V. , Zaitseva N. N. 
Published: February 2025

The aim of the study was to determine characteristics of COVID-19 epidemic process in the Volga federal district in 2020–2023.Materials and methods. Analysis of the COVID-19 epidemic process progress was carried out from March 30, 2020 to December 31, 2023. We used information from the website «report.gsen.ru», materials from the national platform for the aggregation of SARS-CoV-2 genome data — VGARus, the official website of Rospotrebnadzor, the information portal Stopcoronavirus rf, data from the official World Health Organization (WHO) website, weekly reports submitted by the Rospotrebnadzor of the subjects of the Volga Federal District.Results and discussion. The average district incidence rate of a new coronavirus infection was 1280.70/0000 in 2020, 3863.00/0000 in 2021, 7352.20/0000 in 2022, 1398.30/0000 in 2023. In the period from 2020 to 2023, the prevalence of persons aged 30–49 years and 50–64 years in the structure of COVID-19 cases was recorded. The largest proportion of severe cases was recorded in 2022 and 2023 (58.8% and 57.9%, respectively), the smallest — in 2020 (37.6%). The average district mortality and lethality rates were — 20.60/0000 and 1.6% in 2020, 150.80/0000 and 3.9% in 2022, 46.90/0000 and 0.6% in 2022, 3.00/0000 and 0.2% in 2023 respectively.Conclusion. In the period 2020–2023, the COVID-19 incidence rate in general in the Volga Federal District varied, there was an increase in the proportion of mild severe cases, as well as a decrease in mortality and lethality rates, which is associated with a change in circulatingSARS-CoV-2 genovariants, the formation of population immunity, and the organization of a comprehensive system of anti-epidemic measures.
Duration of SARS-CоV-2 virus shedding in COVID-19 patients with HIV infection
Authors: Lioznov D. A. , Pobegalova O. E. , Sabadash N. V. , Karnaukhova E. Yu. , Antonova T. V. , Komissarov A. B. , Ivanova A. A. 
Published: February 2025

The aim: to describe the duration of SARS-CoV-2 virus shedding in patients with HIV infection and to identify factors associated with prolonged viral shedding.Materials and methods: in a prospective study, the clinical and laboratory characteristics of COVID-19 and HIV infection and the duration of SARS-CoV-2 virus shedding were compared in 170 patients, titers of virus neutralizing antibodies to SARSCoV-2 were identified in 68 patients; pathogen genotyping was performed in 36 patients. Statistical analysis was carried out using the IBM SPSS Statistics package.Results and discussion: there were no significant differences in the duration of SARS-CoV-2 virus shedding in patients with varying severity grade of COVID-19; a negative relationship between the titer of virus neutralizing antibodies to SARS-CoV-2 and viral shedding duration was revealed. In 35.9% of patients (61 persons), the persistence of the virus lasted for more than 21 days, this group was characterized by an unfavorable course of HIV infection in the absence of ART, significantly lower CD4 cell values and a higher HIV viral load in the blood. Virus shedding was shown to be significantly longer in patients with B.1.1 strain versus other SARS-CoV-2 gene variants. Mutations in the Spike protein gene that increase the infectious ability of the pathogen and reduce its sensitivity to neutralizing antibodies were found in 4 patients.Conclusion: the severity of COVID-19 did not affect the duration of SARS-CoV-2 virus shedding in patients with HIV infection. Long-term persistence of the virus was discovered in patients with severe immunodeficiency (CD4<200 cl/μl) in the absence of ART. Patients with prolonged viral shedding pose an epidemiological risk in regard to developing new mutational variants of the pathogen.
Managing and responding to the crisis of sexual harassment at the University of Argopuro
Authors: Wulandari Maulina Pia , Layna Nadia Luitsa 
Published: February 2025

Background: Sexual harassment incidents at higher education institutions can trigger crises that have a detrimental impact on public trust and institutional reputation. Purpose: This study analyzes the crisis management and reaction approach employed by the University of Argopuro in the aftermath of a sexual harassment event involving its Rector. Methods: The study employed a qualitative case study approach and collected data through in-depth interviews with senior administrators and document analysis. Results: The findings reveal that the university implemented a five-step crisis management model, integrating adaptive strategies with Image Restoration Theory (IRT) and Situational Crisis Communication Theory (SCCT). These strategies focused on transparency, accountability, and victim protection. The study highlights those key methods, including appointing a spokesperson, issuing press releases, forming a crisis management team, and establishing a Gender Studies Centre to foster systemic reform and prevention. The study offers four novel crisis response strategies: attitude statements for transparency, victim protection plans, organizational accountability mechanisms, and follow-up initiatives to sustain cultural transformation. While SCCT and IRT provided a foundational framework, this study highlights the limitations of the frameworks in addressing the deeper systemic issues surrounding sexual harassment, emphasizing the need for long-term cultural change. Moreover, the results highlight the need to integrate crisis communication theories with adaptive, victim-centered approaches to address preventable crises effectively. Conclusions: The study concludes that a comprehensive and transparent crisis management process can mitigate reputational damage, restore stakeholder trust, and promote systemic reforms. Implications: The study contributes to public relations literature by establishing the applicability of combined theoretical and adaptive strategies in complex academic crises, recommending practical insights for public relations practitioners in higher education institutions worldwide. Future research should expand the application of these strategies across diverse cultural and organizational contexts to validate their effectiveness.
Phenolic profile, antioxidant capacity, and in vivo sub-acute toxicity evaluation of Calligonum comosum L. aerial part
Authors: Laib Ibtissam , Mehda Smail , Attia Hanane , Attia Raounek , Diab Feriel , Khiari Rayhana 
Published: February 2025

Abstract
This study provides a comprehensive analysis of the phenolic constituents and antioxidant properties of C. comosum, complemented by an evaluation of its acute toxicity in vivo. Employing spectrophotometric techniques, we quantified the total polyphenol content (TPC) and total flavonoid content (TFC) using gallic acid and quercetin standards, respectively. High-performance liquid chromatography (HPLC) was utilized to identify and quantify individual phenolic compounds. Antioxidant efficacy was measured through assays assessing total antioxidant capacity, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, and reducing power (RP). The analysis revealed a substantial polyphenol content of 185.073 mg GAE/g DW and a flavonoid content of 21.75 mg QE/g DW. HPLC detected eight distinct phenolic compounds, with quercetin and rutin emerging as the most predominant. The aqueous extract of C. comosum exhibited pronounced antioxidant activity, with significant inhibition across the tested assays. Acute toxicity studies on Wistar rats indicated a favorable safety profile, showing no mortality or significant behavioral changes at doses up to 2000 mg/kg. In conclusion, C. comosum demonstrates a rich reservoir of secondary metabolites with substantial antioxidant potential, affirming its potential as a candidate for therapeutic applications. However, additional in vivo studies are essential to fully elucidate its therapeutic efficacy and safety profile.
Biocompatibility of cleaning agents for ocular prostheses
Authors: Andreotti Agda Marobo , de Caxias Fernanda Pereira , da Silva Emily Vivianne Freitas , de Oliveira Gonçalves Letícia , de Oliveira Sandra Helena Penha , Brito Victor Gustavo Balera , Goiato Marcelo Coelho , dos Santos Daniela Micheline 
Published: February 2025

Abstract
This study aimed to access the cytotoxicity, on the human conjunctival cell line, of different agents (neutral soap, 4% chlorhexidine, Efferdent effervescent tablets, 1% triclosan, and citronella essential oil) used for cleaning ocular prosthesis. Human conjunctival cell line was cultivated on acrylic resin specimens and the cytotoxicity of the studies cleaning agents was evaluated by MTT, Neutral Red, and RTPCR (Real-time reverse transcription polymerase chain reaction) for the gene expression of type IV collagen, transforming growth factor β, myeloid cell leukemia sequence 1, matrix metalloproteinase 9, and caspases 3 and 9. Data were submitted to the two-way analysis of variance (ANOVA) and Bonferroni (p<0.05) tests. All cleaning agents showed biocompatibility for the human conjunctival cells. This, immersion in 4% chlorhexidine, effervescent tablets, and 1% triclosan could be the best protocols indicated for ocular prosthesis cleaning due to their biocompatibility.
Oxidative stress parameters and histopathological lesions in the liver and kidneys of manganese intoxicated rats
Authors: Zawadzki Marcin , Śliwińska-Mossoń Mariola , Szpot Paweł 
Published: February 2025

Abstract
The aim of the research was to verify the theory of the free radical interaction of manganese compounds by assessing the activity of the enzymes: catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR) and glutathione S-transferase (GST) in an experimental rat model of exposure to Mn. Forty five male Buffalo rats were divided into: control, group I (MnCl2; 5 mg/kg b.w.) and groUp II (MnCl2; 7.5 mg/kg b.w.). The activity of the enzymes: CAT, GPx, GR and GST activity were determined in the supernatants of the kidneys and liver. The histopathological alterations were evaluated in tissue sections. In rats intoxicated with Mn (group I and II) the decreased CAT and GR activities was observed in the liver, with a significantly lower the all enzymes activities measured in the kidneys. The the lowest CAT, GPx, GR and GST activity were observed in the kidneys of group II rat. An examination of hepatic tissues revealed moderate (group I) and severe (group II) histopathological lesions, with a insignificant lesions oserved in the renal tissues. It has been shown that manganese intoxication has cytotoxic activity in the kidneys and liver, causing an decrease in antioxidant enzymes activity. The observed histopathological changes in the liver tissue suggest sensitivity to oxidative stress in this organ. In the kidneys, despite a significant weakening of the antioxidant defense, insignificant histopathological lesions were found, which suggests a different defense mechanism independent of the antioxidant enzymatic defense.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI EKSPOR UDANG BEKU INDONESIA KE AMERIKA SERIKAT
Authors: Ramanti Ida Ayu Intan , Budiningsih Ni Ketut , Ayuningsasi Anak Agung Ketut 
Published: February 2025

Indonesia is a maritime country with abundant natural resources. There are various types of marine and fishery products that Indonesia has exported. The leading commodities in the fisheries sector is shrimp, where 88.5% of Indonesian shrimp are exported in frozen form. Throughout 2015-2021, the volume of Indonesian frozen shrimp exports to the United States fluctuated. Several factors cause the fluctuation in the volume of frozen shrimp exports. This study aims to determine the effect of United States GDP, export prices, and United States Dollar exchange rates simultaneously and partially on the volume of frozen shrimp exports in Indonesia. This study uses time series data from 2015-2021 in monthly form. The analysis technique used in this study is using multiple linear regression analysis. The results of this study indicate that United States GDP, export prices, and United States Dollar exchange rates have a simultaneous and significant effect on the volume of frozen shrimp exports from Indonesia to the United States. Partially, United States GDP and export prices do not affect while the United States Dollar exchange rate has a positive and significant effect on the volume of frozen shrimp exports from Indonesia to the United States.
PENGARUH PEMAHAMAN PAJAK, SOSIALISASI PAJAK, DAN NORMA SUBJEKTIF TERHADAP KESADARAN PAJAK MAHASISWA PELAKU USAHA
Authors: Sukmayana Ketut Krisnanda Dewi , Hasibuan Henny Triyana 
Published: February 2025

Dalam upaya meningkatkan penerimaan pajak, kementerian keuangan bersama Direktorat Jenderal Pajak saat ini mengajak para generasi muda khususnya mahasiswa dalam meningkatkan pemahaman dan kesadarannya terhadap pajak. Hal ini menyasar pada mahasiswa karena dilihat dari fenomena yang ada terjadi peningkatan pelaku-pelaku usaha muda dari kalangan mahasiswa, sehingga diperlukan tuntunan bagi mahasiswa untuk menyadari kewajiban pajaknya sejak dini. Tujuan dari penelitian ini untuk mengetahui pengaruh pemahaman pajak, sosialisasi pajak, dan norma subjektif terhadap kesadaran pajak mahasiswa pelaku usaha. Penelitian ini dilakukan pada Komunitas Wida Fakultas Ekonomi dan Bisnis Universitas Udayana dengan metode penarikan sampel jenuh sejumlah 43 orang. Pengumpulan data dilakukan menggunakan kuesioner yang disebar secara daring melalui google form. Data yang dikumpulkan kemudian diolah menggunakan Statistical Package for the Social Sciences (SPSS) dengan teknik analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa pemahaman pajak dan sosialisasi pajak berpengaruh positif dan signifikan terhadap kesadaran pajak mahasiswa pelaku usaha. Namun, variabel norma subjektif yang dikategorikan menjadi keluarga, dosen, dan kerabat tidak memiliki peran dalam memengaruhi tingkat kesadaran pajak mahasiswa pelaku usaha.
Duration of Work and Body Position on Carpal Tunnel Syndrome among BNI Employees in Denpasar City
Authors: Sancitawati Ida Ayu Diah , Saraswati Ni Luh Putu Gita Karunia , Juhanna Indira Vidiari , Pramita Indah 
Published: February 2025

Introduction: Typing activities at work involving repetitive movements with static body posture, if not adequately addressed, can lead to Carpal Tunnel Syndrome (CTS). Data from the National Health Interview Study (NHIS) shows that the incidence rate of CTS in the general population is 2.6 million. Bank employees are one of the professions prone to CTS due to their computer typing activities. This study aims to determine the relationship between the duration of work and body position during typing and the occurrence of CTS among computer users at BNI in Denpasar City.
Methods: This study used a cross-sectional study design and purposive sampling technique for subject recruitment. The total sample size in this study was 86 BNI employees who use computers in Denpasar City. Data collection was conducted through interviews to determine the duration of work and specific examinations such as Phalen’s and Tinel’s tests, and researchers measured the body position of employees during typing using the Rapid Upper Limb Assessment (RULA).
Results: The chi-square test analysis yielded a p-value of 0.039, indicating a relationship between the duration of work and the occurrence of CTS, and a p-value of 0.002, indicating a relationship between body position during typing and CTS.
Conclusion: The study concludes that there is a relationship between the duration of work and body position during typing and the occurrence of CTS among computer users at BNI in Denpasar City. Providing ergonomic training and education by the institution, managing work time and modifying workstations, followed by light stretching by the subjects, can reduce the risk and severity of CTS occurrences.

Keywords: carpal tunnel syndrome, duration of work, body position during typing
Контур истории «Известий Восточного института»
Authors: БАРБЕНКО Ярослав Александрович 
Published: February 2025

История «Известий Восточного института» является отражением гораздо более широких явлений, чем научная издательская деятельность. Возникнув в самом конце XIX в. как часть процесса становления научного практического востоковедения во Владивостоке, журнал сохранил практическую направленность и в XXI в. «Известия» пережили войны и революции первой четверти XX в. в России, в 30‑е гг. оказались вытесненными другими изданиями, но в начале 90‑х гг. были возрождены неравнодушными и трудолюбивыми востоковедами. За прошедшие тридцать лет «Известия» превратились из ежегодника в квартальное издание и стали популярной дискуссионной площадкой для востоковедов и представителей смежных направлений науки.
The history of the Oriental Institute Journal is a reflection of much broader phenomena than scientific publishing. Having emerged at the very end of the 19th century as part of the process of formation of scientific practical Oriental studies in Vladivostok, The Journal retained its practical focus and in the 21st century The Journal survived the wars and revolutions of the first quarter of the 20th century in Russia, in the 30s was replaced by other publications, but in the early 90s they were revived by caring and hardworking Orientalists. Over the past thirty years, The Journal has transformed from a yearbook into a quarterly publication and has become a popular discussion platform for Orientalists and representatives of related research fields.
Uji fitokimia kandungan fenolik ekstrak daun Ginkgo biloba
Authors: Hilmi Fakih , Frans Ferdinal  , Yulianti Eny 
Published: February 2025

Teh daun Ginkgo biloba atau suplemen ekstrak Ginkgo biloba menjadi salah satu pengobatan herbal yang terkenal sebagai suplemen daya ingat. Kandungan senyawa fenolik dalam tanaman herbal telah dilaporkan sebagai zat antioksidan yang berguna untuk memerangi reactive oxygen species (ROS). Kapasitas total antioksidan Ginkgo biloba penting untuk diketahui sebagai pertimbangan penggunaannya dalam produk nutraceutical atau kosmetik. Studi ini bertujuan untuk mengetahui kemampuan antioksidan dan kandungan fenolik ekstrak daun Ginkgo biloba. Desain studi menggunakan eksperimental in vitro. Proses ekstraksi dilakukan menggunakan metode maserasi dengan ethanbol sebagai pelarut. Analisis meliputi uji fitokimia, uji kapasitas antioksidan menggunakan 1,1-Diphenyl-2-Picrylhydrazyl (DPPH), 2,2-azinobis-3-Ethylbenzothiazoline-6-Sulfonic Acid (ABTS), Ferric Reducing Antioxidant Power (FRAP), dan uji brine shrimp lethality test (BLST). Uji fitokimia menunjukkan ekstrak daun Ginkgo biloba positif mengandung senyawa alkaloid, fenolik, glikosida, flavonoid, kuinon, saponin, tannin, kumarin, antosianin, steroid, dan terpenoid. Uji kapasitas total antioksidan berdasarkan metode DPPH menunjukkan ekstrak daun Ginkgo biloba memiliki nilai IC50 563,307 µg/mL, dengan metode ABTS IC50 sebesar 28,821 μg/mL, dan dengan metode FRAP IC50 sebesar 14,17 µg/mL. Seluruh uji kapasitas total antioksidan menunjukkan ekstrak daun Ginkgo biloba tergolong antioksidan yang kuat. Uji BSLT mendapatkan hasil nilai 295,121 µg/mL yang menunjukkan ekstrak daun Ginkgo biloba tergolong toksik dan berpotensi sebagai antimitotik.
Pengaruh Pengelolaan Biaya Logistik dan Infrastruktur Transportasiterhadap Kinerja Logistik Nasional Indonesia
Authors: Kurniawan Ferdy Trisanto , Soekirman Atong , Gautama Idris , Ricardianto Prasadja 
Published: February 2025

Permasalahan utama dari penurunan Kinerja Logistik Nasional di Indonesia menurut LPI (2023) yaitu pada variabel pengiriman internasional, kualitas dan kompetensi logistik, pelacakan & penelusuran, dan ketepatan waktu. Dampak dari penurunan kinerja logistik Indonesia menyebabkan biaya logistik mahal dan eksternalitas seperti kemacetan, gas emisi buang, kerusakan jalan. Reformasi ekosistem logistik nasional (NLE) yang dilakukan pemerintah sampai dengan saat ini diharapkan dapat memberikan kemudahan dan penyederhanaan proses hulu hingga hilir agar berdampak pada waktu dan biaya yang efisien. Dengan demikian, diharapkan ini dapat berdampak pada turunnya biaya logistik dari 23,5% menjadi 17% sehingga bisa disimpulkan bahwa dalam meningkatkan kinerja logistik nasional, pemerintah fokus pada penurunan biaya logistik dan infrastruktur pendukung kinerja logistik nasional. Sesuai dengan penjelasan di atas, maka tujuan dari penelitian ini adalah menganalisis pengaruh variabel pengelolaan biaya logistik dan infrastruktur terhadap kinerja logistik di Indonesia. Lokasi penelitian dilakukan di empat Pelabuhan Hub Internasional yaitu Pelabuhan Belawan Medan, Pelabuhan Tanjung Priok Jakarta, Pelabuhan Tanjung Perak Surabaya, dan Pelabuhan Soekarno Hatta Makassar. Penelitian ini menggunakan metode gabungan yaitu analisis data kualitatif melalui Focus Group Disscusion terhadap narasumber yang kompeten dalam bidang logistik yang dianalisis dengan Aplikasi Nudist In Vivo. Selanjutnya dilakukan analisis data kuantitatif melalui kuesioner pada responden pelaku logistik di empat pelabuhan sampel dan dilakukan anlisis SEM dengan SMARTPLS (Partial Least Square). Hasil penelitian dari analisis SEM PLS menunjukkan bahwa 1) Pengelolaan biaya transportasi berpengaruh positif terhadap kinerja logistik di Indonesia melalui teknologi informasi sebagai mediasi sebesar skor yang didaptkan adalah 0,057; 2) pengelolaan biaya pergudangan, inventori, dan administrasi berpengaruh positif terhadap kinerja logistik di Indonesia masing-masing sebesar 0,018, 0,07, dan 0,03, serta 3) infrastruktur berpengaruh positif terhadap kinerja logistik di Indonesia melalui hub perdagangan sebagai mediasi sebesar 0,27. Rekomendasi dari hasil penelitian ini bahwa untuk meningkatkan kinerja logistik nasional di Indonesia, pemerintah dapat berfokus pada 1) perbaikan dan peningkatan infrastruktur pelabuhan sebagai hub perdagangan untuk meningkatkan konektivitas backbone dan hinterland logistik nasional dan 2) memanfaatkan teknologi informasi untuk meningkatkan kinerja pengelolaan biaya transportasi agar dapat mendorong kinerja logistik.