bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using generalized audit software to detect material misstatements, control deficiencies and fraud
Authors: Bradford Marianne , Henderson Dave , Baxter Ryan J. , Navarro Patricia 
Published: January 2020

Purpose
As technology integration in auditing continues to grow, it is important to understand how auditors perceive connections between use of generalized audit software (GAS) and audit benefits.

Design/methodology/approach
The DeLone and McLean information systems success model (2003) is adapted with audit-related uses of GAS as antecedents to information quality. Survey data on 188 current users of GAS, who are financial and IT auditors, is analyzed with partial least squares method.

Findings
For financial auditors, detecting material misstatements antecedent is the only significant indicator of information quality for GAS. For IT auditors, detecting control deficiencies and fraud significantly impacts information quality. Information quality influences use for both auditors; however, it only influences satisfaction with GAS for financial auditors. System quality impacts GAS satisfaction for only IT auditors and has no impact on GAS use for either type of auditor. Service quality influences use of GAS for financial, but not IT auditors. For both groups, service quality has no impact on satisfaction with GAS, and GAS use and satisfaction with GAS positively increases their perceptions of audit benefits.

Originality/value
Financial and IT auditors who use GAS are both focused on matching GAS use with their primary audit objectives. Results suggest that as GAS use increases, system quality may be important to satisfaction. Training should first focus on the usefulness of GAS to the audit to increase extent of use. Lastly, the more auditors use GAS and are satisfied with it, the greater their perception GAS contributing directly to benefit the audit.
What makes a Chief Digital Officer successful?
Authors: Berman Saul , Baird Carolyn Heller , Eagan Kevin , Marshall Anthony 
Published: January 2020

Purpose
A new IBM Institute for Business Value (IBV) study has now found that the appointment of a CDO–along with a robust digital transformation program–is strongly correlated with stronger corporate financial performance.

Design/methodology/approach
IBM IBV surveyed more than 1,500 business executives in 23 countries and across eighteen industries, of which 750 were CDOs. Based on our analysis, we have created a framework to determine under what circumstances it makes sense to appoint a CDO, and if a CDO is appointed, the set of CDO characteristics and responsibilities that are most likely to yield maximum business benefits and returns.

Findings
The analysis indicates top CDOs’ strongest characteristic is actually business strategy, not technology. The data indicates there is a higher positive financial impact when a CDO reports to the CIO—not when they report to a CEO

Practical implications
Top CDOs take a balanced approach toward transformation. They seem to be evolutionaries and not revolutionaries.

Originality/value
The study found that, contrary to conventional expectations, CDOs most valuable skill could well be their ability to think and act strategically.
A position-sensitive electronic skin based on boundary potential projection theory
Authors: Zhang Youzhi , Lin Zhengkang , You Xiaojun , Huang Xingping , Ye Jinhua , Wu Haibin 
Published: January 2020

Purpose
This paper aims to report a flexible position-sensitive sensor that can be applied as large-area electronic skin over the stiff media.

Design/methodology/approach
The sensor uses a whole piezoresistive film as a touch sensing area. By alternately constructing two uniform electric fields with orthogonal directions in the piezoresistive film, the local changes in conductivity caused by touch can be projected to the boundary along the equipotential line under the constraint of electric field. Based on the change of boundary potential in the two uniform electric fields, it can be easy to determine the position of the contact area in the piezoresistive film.

Findings
Experiment results show the proposed tactile sensor is capable of detecting the contact position and classifying the contact force in real-time based on the changes of the potential differences on the boundary of the sensor.

Practical implications
The application example of using the sensor sample as a controller in shooting game is presented in this paper. It shows that the sensor has excellent touch sensing performance.

Originality/value
In this paper, a position-sensitive electronic skin is proposed. The experiment results show that the sensor has great application prospects in the field of interactive tactile sensing.
The responsible learning organization
Authors: Hansen Jens Ørding , Jensen Are , Nguyen Nhien 
Published: January 2020

Purpose
This study aims to investigate whether the learning organization, as envisioned by Peter Senge in The Fifth Discipline (1990), facilitates responsible innovation.

Design/methodology/approach
The authors analyze the component characteristics of the learning organization as defined by Senge (1990) to identify any conceptual or causal connections to responsible research and innovation (RRI). To define RRI, the authors make use of a commonly cited framework from the academic literature that is consistent with the vision of RRI promoted in European Union policy.

Findings
The authors find significant complementarities between being a learning organization and practicing responsible innovation. Some of the practices and characteristics of a learning organization in the sense of Senge (1990) do not merely facilitate RRI, they are RRI by definition. One important caveat is that to qualify as a responsible innovator according to the proposed framework, an organization must involve external stakeholders in the innovation process, a requirement that has no parallel in The Fifth Discipline. The authors conclude that there is at most a small step from being a learning organization to becoming a responsibly innovating learning organization.

Originality/value
The authors propose a reconsideration of the scope of applicability of Senge’s theory, opening new possibilities for drawing inspiration from The Fifth Discipline 30 years after the book was first published. The authors conclude that there may be significant non-economic advantages to being a learning organization, and that The Fifth Discipline may be more valuable for its ethical perspectives on the organization than as a prescription for how to achieve business success.
Long-chain Brønsted acidic ionic liquids catalyzed one-pot three-component Biginelli reaction
Authors: He Leqin , Qin Shenjun , Liu Jianjun , Zhao Wei , Chang Tao 
Published: January 2020

PurposeFrom the atom economy and environmentally friendly point of views, the development of clean and green approaches using ionic liquids (ILs) as recyclable catalysts has attracted increasing attention. The purpose of this study is to investigate the effect of task-specific ILs content on the one-pot three-component Biginelli reaction.Design/methodology/approachA series of halogen-free quaternary ammonium ILs functionalized with –SO3H group were prepared and characterized by1H nuclear magnetic resonance (NMR),13C NMR and electrospray ionization mass spectrometry. The ILs were used as catalysts for Biginelli reaction among aromatic aldehydes, urea or thiourea and β-dicarbonyl compounds. Anions and cations of ILs were varied to observe their effects on and contributions to the catalysts. The influencing factors, such as the amount of catalyst, solvent, reaction time and reaction temperature, were investigated.FindingsThe effect and contribution of cations of ILs were observed. Results showed that 3-(N, N-dimethylhexadecylammonium) propanesulfonic acid toluene sulfate ([DHPA][Tos]) showed comparable catalytic activity. Good adaptability to the reaction substrate and maximum product yield was observed when [DHPA][Tos] was used as catalyst. It was found that Biginelli reaction catalyzed by 10 mol% [DHPA][Tos] for 3 h under solvent-free conditions at 80 °C gave the best yield of 94%. Post-processing steps were simple, and the catalyst could be reused easily.Originality/valueThis paper demonstrates that ILs containing a long carbon chain and a bulky Tos anion efficiently promoted the reaction, in which the long carbon chains facilitate mass transfer in the reaction system.
CFD investigation of temperature distribution, air flow pattern and thermal comfort in natural ventilation of building using solar chimney
Authors: Dhahri Maher , Aouinet Hana 
Published: January 2020

Purpose
The purpose of this study is to investigate air flow, temperature distribution and thermal confort in natural ventilation induced by solar chimney for different operating.

Design/methodology/approach
Numerical simulation is performed using a commercial computational fluid dynamics (CFD) package ANSYS CFX software to understand the effects of air temperature, air velocity and solar heat flux on the performance of the solar chimney and thermal comfort. The comfort level was evaluated using the air diffusion performance index (ADPI) according to ASHRAE (55-210). The flow was investigated at inclination angles 45° solar heat flux 550-750 W/m2 and in a solar chimney of 1.4 m length, 0.6 m width and 0.20 m air gab.

Findings
The numerical results from the present simulation were first validated with experimental data, which was used for the thermal comfort indexes calculation. The obtained results of the analysis showed that the used numerical technique could accurately predict air flow and temperature distribution in natural ventilated building using solar chimney; the air temperature, air velocity and solar heat flux have a significant impact on thermal comfort; the temperature of 19°C with velocity of 0.15 m.s−1 gives the best effective draft temperature (EDT) satisfy ASHRAE (55-210) criteria that V = 0.35 m.s−1 and EDT range between −1.7 and 1.1.

Originality/value
In the present paper, air flow, temperature distribution and thermal comfort inside a room equipped with inclined solar chimney were numerically investigated and analyzed. The commercial CFD package (CFX 15) is used. Calculations are carried out in an empty room without any human or mechanical activity and the numerical results are compared with measurement points.
Relationship between screen‐time and hand function, play and sensory processing in children without disabilities aged 4–7 years: A exploratory study
Authors: Dadson Paula , Brown Ted , Stagnitti Karen 
Published: January 2020

AbstractIntroductionScreen‐time has become a regular occupation for young children at home and school, with little evidence of its impact on children's developmental skills. This study explored the association between children's screen‐time, fine motor, in‐hand manipulation (IHM), visual‐motor integration (VMI), sensory processing (SP) and parent‐reported play skills.MethodThe fine motor, IHM, VMI, SP and play skills of a sample of 25 Australian children without disabilities (M age = 6.2 years, SD = 1.03; 64% girls) were assessed using the Bruininks–Oseretsky Test of Motor Proficiency—Second Edition, Test of In‐Hand Manipulation—Revised, Berry Buktenica Developmental Test of Visual‐Motor Integration Sixth Edition, Sensory Processing Measure—Home Form and Pretend Play Enjoyment Developmental Checklist (PPEDC). Parents completed a week‐long log of their child's screen‐time. Spearman's rho correlations and linear regressions with bootstrapping were used for data analysis.ResultsStatistically significant moderate level negative correlations were found between Total Screen‐Time (TST) and VMI skills (r = −.67, p < .01); Interactive Screen‐Time and IHM abilities (r = −.46, p < .05) and TST and bilateral coordination skills (r = −.42, p < .05). There were significant negative correlations between SP ability and both TST (r = −.53, p < .01) and Watching Screen‐Time (r = −.66, p < .01). When the PPEDC Object Substitution variable was entered into a regression model as a co‐variate of hand function, it appeared to lessen the impact of TST as an independent predictor variable of children's VMI and bilateral coordination skills (p < .23 and p < .61).ConclusionPlaying with toys and using object substitution in play (e.g. a child uses an object for something else other than its intended use when playing with it) potentially appear to be a moderating factor of the impact of children's screen‐time on their bilateral coordination and VMI skills. Clinicians can encourage children's active and dynamic involvement in games and play pursuits to counteract the potential impact of increased use of devices that involve screen‐time.
The interactive effect of location, alcohol consumption and non‐traffic injury
Authors: Ye Yu , Cherpitel Cheryl J. , Witbrodt Jane , Andreuccetti Gabriel , Room Robin 
Published: January 2020

AbstractAimThis study aimed to assess the extent to which the association between recent alcohol consumption and risk of non‐traffic injury varies according to location at the time of the injury.DesignCase–cross‐over design.Setting and participantsA total of 15 625 injury patients from 49 emergency departments (EDs) in 22 countries.MeasurementsRecent alcohol consumption and location at the time of the injury were assessed for when the injury occurred and for the same time 1 week prior to this. The confounding and interactive effects of location were examined by estimating the adjusted odds ratio (OR) of injury from alcohol consumption adjusting for location and then by examining the alcohol consumption × location interaction.FindingsThere were significant interactive effects of location and alcohol consumption on injury risk. For example, the ORs for volume 0.1–3.0 drinks and street/public place each were 3.0 and 14.2, respectively, whereas the OR for their joint effect was 44.1, suggesting a positive additive interaction [relative excess risk due to interaction (RERI) = 27.9, P < 0.05] and zero multiplicative interaction (OR = 1.0, P = 0.895). The interactions of alcohol consumption with drinking establishment location, work‐place and other locations were mostly additive and negative on the multiplicative scale (e.g. for interaction between volume 0.1–3.0 drinks and drinking establishment location: RERI = 1.19, P = 0.529; multiplicative interaction OR = 0.54, P < 0.05).ConclusionsLocation appears to influence the relationship between alcohol consumption and risk of injury. The association between alcohol consumption and injury appears to be greater in locations such as streets and public places compared with private residences.
LLETZ make it simple: Anxiety, pain and treatment outcomes with outpatient large loop excision of the transformation zone under local anaesthesia
Authors: Yap Shui‐Jean , Nathan Elizabeth , Farrell Louise 
Published: January 2020

BackgroundLarge loop excision of the transformation zone (LLETZ) is the preferred treatment for cervical intraepithelial neoplasia due to its effectiveness and ability to be performed in an outpatient setting under local anaesthesia (LA). Although current guidelines recommend that most LLETZ can be performed under LA, there is paucity in clinical data of patients' perspectives of outpatient LLETZ.AimDetermining patient acceptability of outpatient LLETZ through assessment of anxiety and pain scores, and comparing treatment outcomes with current standards in terms of margins status, negative histology, short‐term morbidity rates and follow‐up attendance.Materials and MethodsThis study was conducted at a tertiary hospital over two years (2014–2016). Patients undergoing outpatient LLETZ completed a three‐part questionnaire (before, immediately after and 4–6 weeks post‐procedure).ResultsOne hundred and five patients underwent outpatient LLETZ. Mean pain score was 2 (range 0–8). Pre‐procedure anxiety was common but most resolved post‐procedure. Women who did not have a prior LLETZ discussion were more likely to report moderate‐severe anxiety levels pre‐procedure, compared with women who did (odds ratio 3.00, 95% CI 1.11–8.09, P = 0.030). There were no differences found in pain scores when comparing pre‐procedure anxiety levels, prior discussion of LLETZ or mode of anaesthesia. Specimen margins were involved in 42.9%. No association was found between positive cervical margin status and age, pre‐procedure anxiety or post‐procedure pain scores. Most patients were satisfied and attended follow‐up appointments.ConclusionLarge loop excision of the transformation zone under LA is a well‐tolerated procedure with high satisfaction and follow‐up rates. Clinicians need to initiate early discussions regarding treatment to minimise procedure‐related anxiety.
Prevalence of third molars determined by panoramic radiographs in a population‐based survey of adult Finns
Authors: Ventä Irja , Vehkalahti Miira M. , Huumonen Sisko , Suominen Anna L. 
Published: January 2020

AbstractObjectivesThe aim of the study was to examine the prevalence of third molars in panoramic radiographs in a population‐based study of adults aged ≥30 years.MethodsOut of a sample of 8028 inhabitants of Finland, selected with two‐staged stratified cluster‐sampling method for the Health 2000 Survey, 5989 participated in clinical oral examination and panoramic radiography. Mean age was 52.5 years (SD 14.6; range 30‐97 years). The following variables were included in the analysis: participant characteristics, clinical number of all teeth, and radiographic prevalence and characteristics of third molars. Statistics included chi‐squared, Fisher's exact, and Kruskal‐Wallis tests and SAS‐SUDAAN calculations.ResultsA total of 5912 third molars in 47.8% of the study population were recorded from panoramic radiographs. At least one impacted third molar was found in 21.9% of the study population. More than half (57.3%) of the remaining third molars were located in the mandible. A preponderance of participants with all third molars missing were observed in the oldest age group, women, those with lower education and those living in the countryside. Third molars or remnants thereof were observed radiographically in 3.9% of clinically edentulous study population.ConclusionsThe panoramic radiographs disclosed many remaining third molars in adult Finns aged ≥30 years. One‐third of the third molars located impacted which may cause unexpected need for care.
Aberrant lipid metabolism in hepatocellular carcinoma cells as well as immune microenvironment: A review
Authors: Hu Bo , Lin Jian‐Zhen , Yang Xiao‐Bo , Sang Xin‐Ting 
Published: January 2020

AbstractHepatocellular carcinoma (HCC) is a primary malignancy of the liver with a high worldwide prevalence and poor prognosis. Researches are urgently needed on its molecular pathogenesis and biological characteristics. Metabolic reprogramming for adaptation to the tumour microenvironment (TME) has been recognized as a hallmark of cancer. Dysregulation of lipid metabolism especially fatty acid (FA) metabolism, which involved in the alternations of the expression and activity of lipid‐metabolizing enzymes, is a hotspot in recent study, and it may be involved in HCC development and progression. Meanwhile, immune cells are also known as key players in the HCC microenvironment and show complicated crosstalk with cancer cells. Emerging evidence has shown that the functions of immune cells in TME are closely related to abnormal lipid metabolism. In this review, we summarize the recent findings of lipid metabolic reprogramming in TME and relate these findings to HCC progression. Our understanding of dysregulated lipid metabolism and associated signalling pathways may suggest a novel strategy to treat HCC by reprogramming cell lipid metabolism or modulating TME.
Development and preliminary evaluation of an animation (simplifyKDPI) to improve kidney transplant candidate understanding of the Kidney Donor Profile Index
Authors: Kayler Liise K. , Majumder Monami , Bonner Keisha , Ranahan Molly , Dolph Beth , Cadzow Renee , Feeley Thomas H. 
Published: January 2020

AbstractBackgroundTransplant candidates are reluctant to accept kidneys from high Kidney Donor Profile Index (KDPI) donors. Incomplete understanding can lead to transplant delays for older transplant candidates. Patients need access to understandable information to make more informed decisions about KDPI.MethodsWe developed a KDPI‐specific animation with input from six stakeholder groups and conducted a one‐group pre‐post study with 60 kidney transplant candidates for feasibility and acceptability to improve participant KDPI knowledge, understanding, decisional self‐efficacy, and willingness to accept a KDPI > 85% kidney. Data were compared using McNemar's test and Wilcoxon signed‐rank test.ResultsCompared with pre‐animation scores, post‐animation scores were significantly higher for KDPI knowledge for the entire cohort (4.6 vs 6.1, P < .001) and across different levels of age, educational attainment, health literacy, vintage, and technology access. The frequency of positive responses increased pre‐post animation for KDPI understanding (55% vs 83%, P < .001) and decisional self‐efficacy (47% vs 75%, P < .001). However, willingness to accept KDPI > 85% kidneys (32% vs 36%, P = .83) increased by 2%. After viewing simplifyKDPI, >90% indicated positive ratings on ease of watching, understanding, and engaging.ConclusionIn collaboration with stakeholders, an educational animation about KDPI was developed that was well‐received and is promising to impact knowledge.
Improved outcomes after live donor renal transplantation for septuagenarians
Authors: Pletcher Jerred , Koizumi Naoru , Nayebpour Mehdi , Alam Zubia , Ortiz Jorge 
Published: January 2020

AbstractThe average age of renal transplant recipients in the United States has increased over the past decade. The implications, however, have not been fully investigated. We explored predictors of success and demographic variables related to outcomes in elderly live donor transplantation. Retrospective analysis was performed using the UNOS database between 2001 and 2016. Donor characteristics and the graft failure rate of recipients above and below 70 years of age were compared across four eras: 2001‐2004, 2005‐2008, 2009‐2012, and 2013‐2016. There was a steady increase in average donor age from the first era to the fourth era (40‐44) which was more evident among the septuagenarian patients (43‐50) (P < .001). The 2‐year graft survival rate improved from 92% in the first era to 96% in the fourth era (P < .001), and this was also more prominent in the >70 population (87%‐93%) (P < .001). The >70 recipients were more likely to be non‐Hispanic white (80.1% vs 65.1%, P < .001) and male (70.1% vs 61.0% P < .001), respectively. The donors were more likely to be non‐Hispanic white and female in the >70 population. Live donation in the elderly is justified based on graft survival and patient survival. However, racial and gender differences exist in septuagenarian recipients and their donors.