bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endoscopic sleeve gastroplasty: suturing the gastric fundus does not confer benefit
Authors: Farha Jad , McGowan Christopher , Hedjoudje Abdellah , Itani Mohamad I. , Abbarh Shahem , Simsek Cem , Ichkhanian Yervant , Vulpis Trish , James Theodore W. , Fayad Lea , Khashab Mouen A. , Oberbach Andreas , Badurdeen Dilhana , Kumbhari Vivek 
Published: August 2020

Abstract
Background There is heterogeneity regarding the technical aspects of endoscopic sleeve gastroplasty (ESG), such as applying fundal sutures. Our aim was to determine whether ESG with fundal suturing (ESG-FS) affects weight loss and the serious adverse event (SAE) rate when compared with ESG with no fundal suturing (ESG-NFS).
Methods We conducted a two-center retrospective analysis of 247 patients who underwent ESG with or without fundal suturing. The primary outcome was percentage excess weight loss (%EWL) at 3, 6, and 12 months post-ESG. The secondary outcomes included the SAE rate and procedure duration.
Results At 3, 6, and 12-months, ESG-NFS had a significantly greater mean %EWL compared with ESG-FS (38.4 % [standard deviation (SD) 15.3 %] vs. 31.2 % [SD 13.9 %], P = 0.001; 54.7 % [SD 19.2 %] vs. 37.7 % [SD 17.3 %], P < 0.001; 65.3 % [SD 21.1 %] vs. 40.6 % [SD 23.5 %], P < 0.001, respectively). There was no statistically significant difference in the SAE rates for ESG-NFS (n = 2; 2.0 %) and ESG-FS (n = 4; 2.6 %; P > 0.99). The mean procedure time was significantly shorter in the ESG-NFS group at 59.1 minutes (SD 32.7) vs. 93.0 minutes (35.5; P < 0.001), and a lower mean number of sutures were used, with 5.7 (SD 1.1) vs. 8.4 (SD 1.6; P < 0.001).
Conclusion ESG-NFS demonstrated greater efficacy and shorter procedure duration. Therefore, fundal suturing should not be performed.
Advanced Pulmonary Sarcoidosis
Authors: Gupta Rohit , Baughman Robert P. 
Published: August 2020

AbstractAt least 5% of sarcoidosis patients die from their disease, usually from advanced pulmonary sarcoidosis. The three major problems encountered in advanced pulmonary sarcoidosis are pulmonary fibrosis, pulmonary hypertension, and respiratory infections. Pulmonary fibrosis is the result of chronic inflammation, but other factors including abnormal wound healing may be important. Sarcoidosis-associated pulmonary hypertension (SAPH) is multifactorial including parenchymal fibrosis, vascular granulomas, and hypoxia. Respiratory infections can be cause by structural changes in the lung and impaired immunity due to sarcoidosis or therapy. Anti-inflammatory therapy alone is not effective in most forms of advanced pulmonary sarcoidosis. New techniques, including high-resolution computer tomography and 18F-fluorodeoxyglucose positron emission tomography (PET) have proved helpful in identifying the cause of advanced disease and directing specific therapy.
APRICOT: Advanced Platform for Reproducible Infrastructures in the Cloud via Open Tools
Authors: Giménez-Alventosa Vicent , Segrelles José Damián , Moltó Germán , Roca-Sogorb Mar 
Published: August 2020

Abstract
Background Scientific publications are meant to exchange knowledge among researchers but the inability to properly reproduce computational experiments limits the quality of scientific research. Furthermore, bibliography shows that irreproducible preclinical research exceeds 50%, which produces a huge waste of resources on nonprofitable research at Life Sciences field. As a consequence, scientific reproducibility is being fostered to promote Open Science through open databases and software tools that are typically deployed on existing computational resources. However, some computational experiments require complex virtual infrastructures, such as elastic clusters of PCs, that can be dynamically provided from multiple clouds. Obtaining these infrastructures requires not only an infrastructure provider, but also advanced knowledge in the cloud computing field.
Objectives The main aim of this paper is to improve reproducibility in life sciences to produce better and more cost-effective research. For that purpose, our intention is to simplify the infrastructure usage and deployment for researchers.
Methods This paper introduces Advanced Platform for Reproducible Infrastructures in the Cloud via Open Tools (APRICOT), an open source extension for Jupyter to deploy deterministic virtual infrastructures across multiclouds for reproducible scientific computational experiments. To exemplify its utilization and how APRICOT can improve the reproduction of experiments with complex computation requirements, two examples in the field of life sciences are provided. All requirements to reproduce both experiments are disclosed within APRICOT and, therefore, can be reproduced by the users.
Results To show the capabilities of APRICOT, we have processed a real magnetic resonance image to accurately characterize a prostate cancer using a Message Passing Interface cluster deployed automatically with APRICOT. In addition, the second example shows how APRICOT scales the deployed infrastructure, according to the workload, using a batch cluster. This example consists of a multiparametric study of a positron emission tomography image reconstruction.
Conclusion APRICOT's benefits are the integration of specific infrastructure deployment, the management and usage for Open Science, making experiments that involve specific computational infrastructures reproducible. All the experiment steps and details can be documented at the same Jupyter notebook which includes infrastructure specifications, data storage, experimentation execution, results gathering, and infrastructure termination. Thus, distributing the experimentation notebook and needed data should be enough to reproduce the experiment.
Counting Polar Symptoms: How to Represent Results?
Authors: Rutten Lex , Eizayaga José , Kaur Harleen , Lamba Chetna Deep , Sachdeva Jyoti , Khurana Anil , Oberai Praveen , Manchanda Rajkumar , Raizada Sonia , Chaudhary Sujata , Shinde Vaishali , Ramanan Vinitha Edavattath , Kundu Chittaranjan , Pal Pratha Pratim , Kiranmayee Rompicherla GR , Sahoo Amulya Ratan , Rajeshekhar Bodankar , Shil Ratan Chandra , Mahajan Nidhi 
Published: August 2020

Abstract
Background Polar symptoms (PS)—symptoms with opposite values—are frequently used in homeopathy, but have many misleading entries in the repertory. This is caused by using absolute occurrence of symptoms, causing the same medicine to appear in both (opposite) symptom rubrics, and by lack of comparison with other medicines. Some PS, like ‘aversion/desire for sweets’ have a frequency distribution that is not evenly distributed around the neutral value: a desire for sweets is much more common than aversion. A desire for sweets is an indication for a specific medicine only if this desire occurs more frequently in this specific medicine population than in the remainder of the population. We need to find the best way to represent this difference.
Methods A multi-centre, explorative, prospective, observational study was conducted by nine centres of the Central Council for Research in Homoeopathy. Two-hundred and sixteen patients were enrolled with chronic cough lasting more than 8 weeks, and received usual homeopathic care. During intake, 30 general PS, 27 polar cough symptoms and 3 non-polar cough symptoms were checked. Different ways of representing results were explored, including two quantities borrowed from mechanics: Centre of Mass (CoM) and Leverage.
Results At the fourth follow-up, three medicines with more than 10 cases with good results were identified: 20 Phosphorus, 19 Pulsatilla and 13 Sulphur. The mean value of the frequency distribution of some symptoms in the whole sample was considerably different from the neutral value. Comparing a medicine population with the remainder of the respective population can give results that differ from polarity analysis. For some symptoms, the ‘distance’ (Leverage) between the CoMs of the medicine population and the remainder of the population was clearer than the likelihood ratio (LR).
Conclusion If the LR value is not clear about the prognostic value in PS, notions from mechanics such as CoM and Leverage can clarify how to interpret a polar symptom.
Tratamiento Artroscópico en Lesión Osteocondral Subtalar
Authors: Sergio Eckholt G. , Javier Palma P. , Eduardo Becerra H. 
Published: August 2020

ResumenLas lesiones osteocondrales de la articulación subtalar es una patología infrecuente y de incidencia variable, dado su reporte principalmente como hallazgo en el estudio de dolor crónico de tobillo y ya con cambios degenerativos articulares. La sospecha clínica y el estudio imagenológico dirigido, permiten investigar esas lesiones en estadios iniciales, evitando así el uso de técnicas que no preservan la articulación para su manejo. La artroscopía subtalar es una excelente herramienta tanto diagnóstica como terapéutica para la resolución de dichas lesiones. Dadas las características anatómicas y biomecánicas de la articulación, en estadios iniciales, el manejo mediante sinovectomía y microfracturas es una alternativa con excelentes resultados funcionales.Este trabajo incluye dos casos de lesiones osteocondrales de la faceta posterior de la articulación subtalar manejadas vía artroscópica mediante sinovectomía y microfracturas y su posterior evolución.
Hepatic Sarcoidosis: Current Concepts and Treatments
Authors: Rossi Geoffrey , Ziol Marianne , Roulot Dominique , Valeyre Dominique , Mahévas Matthieu 
Published: August 2020

AbstractHepatic sarcoidosis is a relatively common manifestation of extrapulmonary sarcoidosis. It occurs in 20 to 30% of cases and is rarely severe. However, a cluster of patients may develop severe complications such as cirrhosis and portal hypertension. In this review, we describe the current knowledge of clinical, biological, pathological, and radiological features of liver involvement in sarcoidosis and discuss essential clues for management and treatment.
Comparative Analysis of Vertical Forces in Dogs Affected with Cranial Cruciate Ligament Disease and Tibial Plateau Angles Greater or Less than 25 Degrees
Authors: Ferrigno Cássio Ricardo Auada , de Souza Alexandre Navarro Alves , Ferreira Márcio Poletto , Verpaalen Valentine , Matera Julia Maria 
Published: August 2020

AbstractObjective Our objective was to compare the peak vertical force (PVF) and vertical impulse (VI) between dogs with cranial cruciate ligament disease and a tibial plateau angle (TPA) greater or less than 25 degrees.Methods A retrospective study was performed in 18 dogs with cranial cruciate ligament disease in which kinetic gait data were obtained with a pressure walkway system. Dogs were distributed in two groups: dogs with a TPA ≤ 25 degrees (n = 8) and dogs with a TPA > 25 degrees (n = 10). Mean PVF and VI in per cent of body weight (%BW) were compared between groups with an unpaired t-test (p < 0.05).Results Mean PVF and VI for the cranial cruciate ligament disease limb were 14.39%BW and 3.57%BWs for dogs with a TPA >25 degrees and 14.44%BW and 3.47%BWs for dogs with a TPA ≤ 25 degrees. There was no significant difference in mean PVF and VI between the groups.Conclusion The results suggest that there is no difference in kinetic data between dogs with cranial cruciate ligament disease and a TPA greater or less than 25 degrees. Other factors such as body weight, time of injury or meniscal lesion could be more related to the magnitude of cranial cruciate ligament disease lameness.
Anatomy and Ultrasound-Guided Injection of the Medial Branch of the Dorsal Ramus of the Cervical Spinal Nerves in the Horse: A Cadaveric Study
Authors: Corraretti Giorgio , Vandeweerd Jean-Michel , Hontoir Fanny , Vanderperren Katrien , Palmers Katrien 
Published: August 2020

AbstractObjective The aim of this study was to describe the anatomy of the nerves supplying the cervical articular process joint and to identify relevant anatomical landmarks that could aid in the ultrasound-guided location and injection of these nerves for diagnostic and therapeutic purposes.Study Design Twelve cadaveric equine necks were used. Five necks were dissected to study the anatomy of the medial branch of the dorsal ramus of the cervical spinal nerves 3 to 7. Relevant anatomical findings detected during dissections were combined with ultrasonographic images obtained in one other neck. Six additional necks were used to assess the accuracy of ultrasound-guided injections of the medial branch with blue dye.Results Each examined cervical articular process joint, except for C2 to C3, presented a dual nerve supply. The articular process joints were found to be in close anatomical relationship with the medial branch of the dorsal ramus of the cervical spinal nerve exiting from the intervertebral foramen at the same level, and with the medial branch of the dorsal ramus of the cervical spinal nerve exiting from the intervertebral foramen one level cranial to the articular process joint of interest. A total of 55 nerves were injected under ultrasonographic guidance, 51 of which were successfully stained.Conclusion The current study provided new detailed information regarding the innervation of the cervical articular process joint. The medial branches of the dorsal rami of the cervical spinal nerves were injected with an accuracy that would be of clinical value. Our study offers the foundations to develop new diagnostic and therapeutic techniques for pain management in cervical articular process joint arthropathy in horses.
Individualized Homeopathy for Depression in Climacteric Women: Comments on the Retraction by PLoS ONE
Authors: Macías-Cortés Emma del Carmen , Llanes-González Lidia , Aguilar-Faisal Leopoldo , Asbun-Bojalil Juan 
Published: August 2020

AbstractIn April 2020 PLoS ONE retracted an original clinical research article, published in 2015, in which we demonstrated that individualized homeopathic treatment improves depression symptoms in climacteric women. The original assessment of this study was carried out by an expert in psychiatry (depression research) with close to 35 years' experience in the field of mental health. During post-publication discussions, no serious breaches of scientific procedure or misconduct were even insinuated. Our team answered all “points of concern”, raised by the current PLoS ONE editors, in extensive detail. All these were potential limitations of our study, which would usually be addressed by one of several appropriate post-publication actions, ranging from discussion of the concern within a systematic review, through to correcting the study itself by adding a correction notice. Therefore, in the interests of transparency and accuracy, a summary of the most relevant points is provided, so that a fair-minded reader can objectively form a clear opinion.
Marginal Bone Level Changes and Oral Health Impact Profile (14) Score of Smokers Treated by Mandibular Mini Implant Overdentures: A 5-Year Follow-up Study
Authors: Hussein Mostafa Omran , Alruthea Mohammed Suliman 
Published: August 2020

Abstract
Objectives Studies considered edentulous patients having smoking habit as a compromised oral condition. This research examined the value of using mini implant mandibular overdenture to maintain long-term satisfactory levels of oral health quality of life and marginal vertical bone loss.
Materials and Methods Twenty-nine edentulous patients with smoking habit received four mini implants in the mandible loaded by overdentures. The present study monitored patients radiographically for vertical bone loss after (1 month, 1, 3, and 5 years) of treatment. Patients were also evaluated by oral health impact profile 14 (OHIP-14) pretreatment and at 1 and 5 years of treatment.
Statistical Analysis Repeated measure analysis of variance with Bonferroni’s test as a post-hoc test was used to see the difference among time points. Independent sample t-tests were used to compare between anterior and posterior mini implant positions after 5 years of follow-up. OHIP-14 questionnaire was analyzed by Wilcoxon signed ranks for pairwise comparisons at different evaluation times. A Holm-Bonferroni correction method was used to control the familywise error rate.
Results The mean of the bone height changes showed a significant difference between 1-month data and all other evaluation intervals while no significance was calculated among other evaluation intervals. Bone loss of the mini implants placed anteriorly was less than those placed posteriorly with a statistically significant difference. A significant reduction in the OHIP-14 score levels was observed between pretreatment and both 1 and 5 years of treatment. No significance was seen between the first and fifth year after treatment.
Conclusion Mini implant overdenture could maintain satisfactory marginal bone level changes and oral health quality of life for patients with smoking habit after 5-year follow-up period.
Clinical, Biochemical, Molecular, and Therapeutic Analysis of Maple Syrup Urine Disease in Upper Egypt
Authors: Dahpy Marwa A. , Saleem Tahia H. , El-Asheer Osama M. , ELrasoul Ahmed Abd , Abo Elgeit Amir M. 
Published: August 2020

AbstractMaple syrup urine disease (MSUD) is an autosomal recessive inherited metabolic disorder caused by mutations in any of the genes encoding for the branched-chain keto dehydrogenase (BCKDH) components. This study screened MSUD patients throughout the whole Upper Egypt describing their symptoms, clinical and laboratory findings, genetic studies, and their treatment, with a 6-month follow-up for their responses. Screening identified three children with MSUD. Homozygous mutation in R195Q single nucleotide polymorphism (SNP) within the BCKDHA gene was found with the second MSUD patient. Follow-up for 6 months to assess the treatment regimens and progression of cases demonstrated that early treatment regimens including a dietary restriction of branched-chain amino acids with L-Carnitine administration could prevent MSUD-associated intellectual disabilities. It was concluded that R195Q SNP is pathogenic, and it may cause inherited forms of MSUD in some patients. MSUD cases have rarely been reported; so these findings will be highly useful for future cases of MSUD in the Upper Egyptian population.
Hoping for success, becoming a spiritual subject
Authors: Pérez-Milans Miguel , Xiaoyan Guo (Grace) 
Published: August 2020

Abstract
This article focuses on the entanglement of trajectories of transnational education/work and religious conversion among
Chinese overseas students who move to the UK before returning to China. In contrast to the existing literature on returnees where the gaze
is only turned on highly prestigious schemes/trajectories of return, we look at those who become involved with Christian evangelical
congregations and bible reading groups in response to a general state of disillusion with social beliefs of global competition and success.
By drawing on ongoing ethnographic fieldwork in London and Beijing, we engage with literature on lived religion, migration and the care of
the self through a sociolinguistic lens. We take pressures for successful return as a technology of hope that shaped our participants’
experiences of Christian conversion, and examine religious practices as support-based subject-transformation projects whereby our
participants regulate their and others’ practices and feelings through daily semiotic activities as they operate within global spaces of
higher education and the labour market. In so doing, we detail a complex interplay of self-transformation experiences, collective practices
of refusal, and capitalist logics of market expansion.
Coloniality, neoliberalism and the language textbook
Authors: Gurney Laura , Díaz Adriana 
Published: August 2020

Abstract
In this article, we question the presumed presence of the textbook as sine qua non in languages
education. Contextualising our discussion within Spanish as a foreign language (SFL) in higher education, we illuminate the overlapping
ideological, historical and economic forces that frame and shape language practice through textbooks. In a field in which decolonial and
poststructuralist approaches to language and languages education are gaining traction, the textbook thwarts theoretical and practical
complexification of language beyond monolingual depictions of languages as ahistorical and context-free systems which unproblematically
transport meaning across time and space. Furthermore, the status of the textbook as a producible and consumable item cannot be overlooked. On
the basis of our critique, we conclude that the use of textbooks generates serious tensions in practice for those wishing to pursue
emergent, emancipatory linguistic frameworks in languages education.
Additions in simultaneous signed interpreting
Authors: Wehrmeyer Ella 
Published: August 2020

Abstract
Until now, investigations of strategies used by signed language interpreters in the simultaneous mode have been sporadic
and restricted to analyses of short transcripts. This article presents the first corpus-driven exploration of interpreter additions in news
broadcasts simultaneously interpreted into South African Sign Language. Using grounded theory, it explores the types of additions made, the
reasons for their production, and their downstream consequences. The results show that interpreters mainly add discourse markers, linguistic
extrapolations such as filling in ellipsis and obvious co-text, repetitions, contextual information, and to a lesser extent, second
translations, pragmatic markers, and new information. However, the cost is high as additions often result in concomitant omissions and
occasional incoherence. From the results, a model is extrapolated to explain additions in terms of the interpreter’s perceived roles and
status in the Deaf community.
Introduction to Biosecurity surveillance: quantitative approaches.
Authors: Jarrad F. 
Published: August 2020

Abstract

This book contains practical and innovative approaches to plant and animal biosecurity surveillance from Australia and around the world, using established and new methodologies, with a particular focus on the quantitative, particularly statistical, aspects of these methods. The book is structured in three parts. Part I supports the later parts of the book, by providing a foundation for describing the statistical modelling methods presented, as well as placing later chapters in the broader international context. The chapters in Parts II and III describe methods and supporting case studies that demonstrate and/or implement the techniques, tools and methods described. Each chapter focuses on particular aspects or concepts of surveillance and typically illustrates these using a case study. While the specifics differ among chapters, the following broad themes are commonly addressed in each chapter: (i) what is the big picture problem?; (ii) what are the main challenges for an evidence-based approach?; (iii) what are the main quantitative modelling solutions?; (iv) what are the main outcomes?; and (v) who is using this/how/why? In summary, this book can be used as a general reference to biosecurity surveillance, as well as a specific reference to frontier methodology used in biosecurity surveillance research and practice. It is hoped that the collation of current statistical modelling methodology that deals with common but complex biosecurity surveillance situations will not only provide informative reading, but will stimulate the identification of existing gaps in this methodology, and corresponding innovative statistical approaches to fill these gaps.