bluuebunny/crossref_metadata_2025_split huggingface dataset:
Corrosion Behaviour of Titanium β Type Ti-12Cr in 3% NaCl Solution
Authors: Fajri Hidayatul , Gunawarman - , Nurbaiti - , Affi Jon , Niinomi Mitsuo , Nur Hadi 
Published: November 2019

Titanium alloy, especially titanium type Ti-12Cr for biomedical application has been a concern of many researchers recently. This titanium has excellent biocompatibility and controllable mechanical properties. Generally, titanium β type contains many alloying elements that lead to a high price. Therefore, it is interesting to develop β type with only one cheap alloying element such as Ti-12Cr that is designed as a low-cost implant material. Initially, Ti-12Cr has been developed, in particular for spinal fixation. Nowadays, the research of Ti-12Cr emphasizes only on mechanical properties. The corrosion behavior of this alloy has not been understood well yet. Therefore, corrosion characteristics of this alloy in any circumstances are necessary to investigate. This paper reports the corrosion behavior of Ti-12Cr in a salted environment using the weight loss method. Ti-12Cr samples were immersed in a 3% NaCl solution for 2, 4, and 6 weeks. Samples consist of Ti-12Cr (as-received), Ti-12Cr (ST) and Ti-12Cr (AT 30 ks). Weight of samples was measured before and after the immersing process using the digital balance. Microstructure and composition of the sample surfaces were examined by using SEM and EDX, respectively. The lowest corrosion rate after exposure for 6 weeks while the highest one is Ti-12Cr (as-received) is Ti-12Cr (AT 30 ks) that is 0,003 mmpy. The microstructure all of the samples shows black spots in the surfaces indicating corrosion has been started to occur on the samples. It was found that the corrosion is due to destruction of the chrome-oxide layer in some weak point as a result of a chemical reaction between the metal (Cr) with Cl- ions. Some oxides are formed on the surface of titanium, as indicated by a significant increment of oxygen content is the corrosive sample surface. This study indicates the corrosion resistance of Ti-12Cr (AT 30 ks) is much better than other materials in this research.
Rheology of The Glutinous Rice Flour, Coconut Milk, and Palm Sugar Mixed System in A Traditional Food Dodol Ulame
Authors: Setiavani Gusti , Sugiyono - , Ahza Adil Basuki , Suyatma Nugraha Edi 
Published: November 2019

Triple mixed of glutinous rice flour, coconut milk, and palm sugar paste with ratio of 1.0:2.5:0.5, 1.0:2.0:1.0, 1.0:1.5:1.5, 1.0:1.0:2.0, 1.0:0.5:2.5 were studied using rapid visco-analyzer (RVA), rheometer, and polarized light microscope to investigate its pasting properties, flow behavior index, dynamic rheology, and microstructure respectively. The power-law and Herschel-Bulkley models were used to evaluate its steady rheological properties. The RVA profile shows low viscosity profile and low breakdown viscosity for all ratio of dodol ulame paste. The lowest breakdown viscosity occurred at the ratio of 1.0:2.5:0. Meanwhile, the highest setback viscosity occurs at the ratio of 1.0:0.5:2.5. Indicating the highest riqidity due to high sugar content. The apparent viscosity decreased with increasing shear rate for all triple mixed exhibited a typical shear-thinning behaviour (n<1) of the system. Increasing the proportion of coconut milk decreased the consistency coefficient, k, and increased the flow behaviour index, n of the system. The dynamic rheology resulted in the higher G” value over the entire frequency. Maltese crosses disappeared at 90 °C for the ratio of system 1.0:0.5:2.5 and 1.0:1.0:2.0 and 80 °C for the ratio of system 1.0:1.0:2.0, 1.0:1.5:1.5 and 1.0:1.0:2.0. The study suggests that coconut milk and palm sugar had an important role on the rheology of dodol ulame paste, consequently it affects the gelatinization, viscosity, and gel-like behaviour of the glutinous rice flour, coconut milk, and palm sugar mixed system. Further study on the preference and nano structure is undertaken to reveal its possibility to produce better quality dodol ulame.
West Sumatera Brown Rice Resistance to Fe
Authors: Dwipa Indra , Suliansyah Irfan , Swasti Etti 
Published: November 2019

Brown rice is favored nutritious rice consumed by urban people whole the world as carbohydrate substitutes. This rice is appropriate for an urban community that concerns to a healthy lifestyle and diabetes people as the main staple food. One indicator of superior brown rice is resistant to abiotic stress, such as Fe. Fe is one of the main problems in cultivated land in Indonesia. The study aimed to study the West Sumatera brown rice resistance to Fe stress. West Sumatera belongs to the one province in Indonesia that can supply 2.5% of Indonesia rice requirement or 2 million tons in 2017. The research was conducted in the shade net house of Faculty of Agriculture, Andalas University, Padang, West Sumatera, Indonesia, from October 2017-January 2018. A completely randomized design was used in the assay and replied 3 times. 15 brown rice genotypes that consisted of 13 brown rice (Surian, Padi Ladang, Talang Babungo, Sungai Abu, Gunung Pasir, Perbatasan, Kekuningan, Pido Manggih, Siarang, Padi Telur, Sikarujuik, Jorong Mudiak and Teluk Embun) and 2 black rice genotypes (Sariak Alam Tigo and Solok) were used in the research. 2 genotypes (IR-42 and IR-64) were used as the control. The result showed that 5 West Sumatera brown rice genotypes were tolerant to Fe stress, Talang Babungo, Perbatasan, Kekuningan, Siarang, and Black Rice Solok. The result also showed that Fe affected the height of the plant, length of root, dry grain weight, and production of grain per pot. Black Rice Solok was the best genotype for grain production per hectare (3.3 ton).
Appropriate Technology of Post Harvest Broccoli Quality Produced in Indonesia
Authors: Bafdal Nurpilihan , Tjahjadi Carmencita , Moodi Debby Sumanti , Pujianto Totok , Hong Seok-In , Kim Dongman 
Published: November 2019

Broccoli is a highly economic crop in Indonesia, it is rich in vitamin and mineral and is a good source of vitamin A; Pottasium; Folic acid ; Iron and Fiber.The best grows of broccoli in area with a cool climate or high land; in West Java cultivated of broccoli were at Lembang and Pangalengan. Broccoli is cultivated for its curd which should be dark green in color. The curd has diameter of 5-25 cm depending on soil conditions and variety. Head of broccoli must be entirely green and all flower buds must be completely closed to be desirable. Quality factors for broccoli consist of curd density, greenness, and absence of blemishes.The problem of broccoli is post harvest handling without appropriate technology and handling is still carried out by traditional method without hardly any starting or grading prior . The quality of the product can not be improved by post-harvest handling a lone, but is necessary for extending shelf-life. Post harvest handling covers the time span from product harvesting in the farm field until it reaches the urban consumer through the market The two main objectives of applying appropriate technology of post harvest of broccoli are to maintain quality and reduce losses between harvest and consumption A descriptive experiment method was done and regression analysis consisting of two variables (dependent and independent) were employed with five treatments. The results showed were all treatment gave various results depend of packaging in a sealed and temperature. Low storage temperature in broccoli more important than type of packaging in maintaining sensory characteristics of the curd and reducing weight loss as well as decay scores. LPDE bag was best cold storage of broccoli curds.
Reseña del libro Antropología del deporte
Authors: Kalfaian Sofia 
Published: November 2019

Destacando la primera frase del libro que aquí se reseña, vale decir que son ciertamente pocas actividades de la vida de las personas que conjugan actividades tan diversas como los ejercicios, las emociones, la política, el dinero, etc. de una manera tan estrecha como en el caso del deporte. El enfoque antropológico resulta, entonces, una aproximación interesante para estudiar las relaciones entre ritual, religión y deporte; así como también las áreas que rodean a este último: la política, la economía y la construcción sobre la idea de cuerpo y género. El libro invita a pensar el contexto de peculiar productividad del deporte para estudiar, a multi-escala, el mundo contemporáneo. Los autores de este libro pivotean entre una evaluación crítica del estado del campo de la antropología del deporte, por un lado, y la diagramación de un programa de futuras indagaciones multi y transdiciplinarias, por otro.
Comparison of sinew-strengthening exercise with cognitive-behavioral therapy for chronic nonspecific low back pain: protocol for a randomized controlled clinical trial
Authors: Peng Peng , Zhao Ye , Zhang Chengzhe , Shen Zhibi , Yuan Weian , Zhan Hongsheng 
Published: November 2019

Abstract
Background: Chronic low back pain is a common disease in clinic. The prevention and treatment of this disease requires a great deal of medical care resources, which is now the third medical economic burden in China. Although non-steroidal analgesics have been shown to be effective for chronic low back pain, considering the obvious side effects of these drugs, more and more patients are inclined to employ non-drug therapies. Typical examples are exercise therapy and cognitive-behavioral therapy (CBT). Exercise therapy of traditional Chinese medicine is an important part of non-drug therapy in China, such as sinew-strengthening exercise (SSE). Originating from traditional Chinese medicine exercise therapy, it has long been used for the prevention and treatment of chronic low back pain in Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine (SGH), but it has not been validated by clinical trials. In this trial, we will seek to determine whether SSE is an effective and safe treatment option for persons with chronic nonspecific low back pain (CNLBP) by comparing it with CBT and explore a new method to CNLBP. Methods/Design: In this trial, we will randomize 480 adults with CNLBP to CBT and SSE arms (240 per group). Participants in both groups will be followed for 52 weeks after randomization with home practice. Interviewers will assess outcomes 4, 8, 12, 26 and 52 weeks postrandomization. The primary measure instrument will be Roland-Morris Disability Questionnaire (RMDQ) with 26-week follow-up being the primary endpoint. Discussion: If SSE is found to be an effective treatment option for patients with chronic back pain, it will become a meritorious addition to the current limited treatment approaches available to patients with significant psychosocial contributors to their pain.
Cerebellopontine angle Choroid plexus papilloma various presentations: report of series and literature review
Authors: Ebrahimzadeh Kaveh , Omidbeigi Mahmoud , Asaadi Sina , Sharifi Guive , Halajnejad Mohammad , Lotfinia Mahmoud , Shool Sina , Rezaei Omidvar 
Published: November 2019

Abstract
Choroid plexus tumors (CPTs) are rare choroid plexus epithelium originated neoplasms. Among all, choroid plexus papilloma (CPP) is the most common type of CPT. Clinical features and signs at diagnosis of CPP in CPA are so extensive and also nonspecific. This work aimed to review the sign and symptoms of CPP tumors in CPA through all cases reported in the literature. In this study, Data regarding presenting symptoms of 60 adult patients (including 53 adult patients identified from the literature and our seven new patients that presented in this study) with CPP in CPA were reviewed. Symptoms related to 8th cranial nerve, lower motor, 7th, and 5th cranial nerves were the most prevalent symptoms respectively following ICP rising and cerebellar signs. The most common symptoms were related to the ICP elevation, cerebellar and auditory system involvement. The rarity of CPP tumors in CPA along with a variety of presenting symptoms makes the diagnosis of CPPs more challenging while considering this variance could be helpful in prompt diagnosis.
Finite volume model for the simulation of 1D unsteady river flow and water quality based on the WASP
Authors: Gordillo Geovanny , Morales-Hernández Mario , García-Navarro Pilar 
Published: November 2019

AbstractIn this work, a one-dimensional (1D) finite volume numerical model for the unsteady simulation of the flow hydrodynamics and water quality is developed. The water dynamics is formulated with the 1D shallow water equations, and the water quality evolution is described by the Water Quality Analysis Simulation Program (WASP) model, allowing us to interpret and predict the transport and fate of various biochemical substances along any river reach. This combined system is solved with an explicit finite volume scheme based on Roe's linearization for the advection component of both the flow and the solute transport equations. The proposed model is able to consider temporal variations in tributaries and abstractions occurring in the river basin. This feature is transcendent in order to predict the chemical composition of natural water bodies during winter and summer periods, leading to an improvement in the agreement between computed and observed water quality evolutions. The combined model has been evaluated using literature tests in a steady state and a real-field case of the Ebro river (Spain), characterized by a marked unsteady regime. In the real case, we found that the water temperature was very sensitive to both the solar radiation and the average air temperature, requiring a careful calibration of these parameters. The numerical results are also demonstrated to be reasonably accurate, conservative and robust in real-scale field cases, showing that the model is able to predict the evolution of quality parameters as well as hydrodynamic variables in complex scenarios.
Translating pathogen knowledge to practice for sanitation decision-making
Authors: Tumwebaze Innocent K. , Rose Joan B. , Hofstra Nynke , Verbyla Matthew E. , Musaazi Isaac , Okaali Daniel A. , Kaggwa Rose C. , Nansubuga Irene , Murphy Heather M. 
Published: November 2019

Abstract
Sanitation planners make complex decisions in the delivery of sanitation services to achieve health outcomes. We present findings from a stakeholder engagement workshop held in Kampala, Uganda, to educate, interact with, and solicit feedback from participants on how the relevant scientific literature on pathogens can be made more accessible to practitioners to support decision-making. We targeted Water, Sanitation and Hygiene (WASH) practitioners involved in different levels of service delivery. Practitioners revealed that different sanitation planning tools are used to inform decision-making; however, most of these tools are not user-friendly or adapted to meet their needs. Most stakeholders (68%) expressed familiarity with pathogens, yet less than half (46%) understood that fecal coliforms were bacteria and used as indicators for fecal pollution. A number of stakeholders were unaware that fecal indicator bacteria do not behave and persist the same as helminths, protozoa, or viruses, making fecal indicator bacteria inadequate for assessing pathogen reductions for all pathogen groups. This suggests a need for awareness and capacity development around pathogens found in excreta. The findings underscore the importance to engage stakeholders in the development of support tools for sanitation planning and highlighted broader opportunities to bridge science with practice in the WASH sector.
New Folate-Modified Human Serum Albumin Conjugated to Cationic Lipid Carriers for Dual Targeting of Mitoxantrone against Breast Cancer
Authors: Ridha Abbas A. , Kashanian Soheila , Azandaryani Abbas H. , Rafipour Ronak , Mahdavian Elahe 
Published: November 2019

Aim:In the present work, folic acid-modified human serum albumin conjugated to cationic solid lipid nanoparticles were synthesized as nanocarriers of mitoxantrone for the treatment of breast cancer.Background:Dual-targeted drug delivery is a new drug dosing strategy that is frequently used to enhance the therapeutic efficacy of anticancer drugs.Objective:Dual targeting of the cancer cells was achieved by dual tagging of human serum albumin and folic acid on the surface of the lipid nanoparticles.Methods:The targeted drug-loaded nanocomplexes were synthesized and characterized using transmission electron microscopy along with photon-correlation and Fourier-transform infrared spectroscopic techniques. The anti-cancer activity of the nanocomplexes was screened against an in-vitro model of MCF-7 and MDA-MB-231 breast cancer cell lines to examine drug efficacy.Results:The entrapment efficiency and drug loading values for mitoxantrone were calculated to be 97 and 8.84%, respectively. The data from the drug release studies for the system indicated the release profile did not significantly change within a pH range of 5.5-7.4. The hemolysis ratio of the hybrid carrier was less than 5% even at the upper doses of 3 mg/mL, demonstrating its safety for intravenous injection with limited hemolysis and a long blood circulation time.Conclusion:The cell cytotoxicity results confirmed that the drug hybrid nanocomplex was more toxic to breast cancer cells compared with the free drug. Furthermore, the weakly cationic and small size particles prevented opsonin binding of nanocomplexes, improving blood circulation time and cancer tissue uptake.
A Novel Drug Repositioning Approach Based on Integrative Multiple Similarity Measures
Authors: Yan Chaokun , Feng Luping , Wang Wenxiu , Wang Jianlin , Zhang Ge , Luo Junwei 
Published: November 2019

Background:
Drug repositioning refers to discovering new indications for the
existing drugs, which can improve the efficiency of drug research and development.

Methods:
In this work, a novel drug repositioning approach based on integrative
multiple similarity measure, called DR_IMSM, is proposed. The process of integrative
similarity measure contains three steps. First, a heterogeneous network can be
constructed based on known drug-disease association, shared entities information for
drug pairwise and diseases pairwise. Second, a deep learning method, DeepWalk, is
used to capture the topology similarity for drug and disease. Third, a similarity
integration and adjusting process is further conducted to obtain more comprehensive
drug and disease similarity measure, respectively.

Results:
On this basis, a Bi-random walk algorithm is implemented in the constructed
heterogeneous network to rank diseases for each drug. Compared with other
approaches, the proposed DR_IMSM can achieve superior performance in terms of
AUC on the gold standard datasets. Case studies further confirm the practical
significance of DR_IMSM.
Social Media as a Means to Disseminate and Advocate Cardiovascular Research: Why, How, and Best Practices
Authors: Lee Giuliana , Choi Andrew D. , Michos Erin D. 
Published: November 2019

:
The use of Twitter or other social media platforms for research can transcend current
limitations in the dissemination of research and present new opportunities for research networking
by connecting researchers, clinicians, policymakers, the public, and other stakeholders on a global
scale. As social media influence continues to expand, it becomes increasingly important for cardiovascular
researchers to employ social media strategies to increase the impact of their research work,
for the ultimate goal of improved outcomes for patients living with or at risk for cardiovascular diseases.
Altmetrics are novel metrics that track the attention that scholarly outputs are receiving in
non-traditional sources such as in the news, blogs, and social media posts. These alternative metrics
record research dissemination beyond traditional journal citation indices, while also predicting and
even promoting future citations. This review outlines various methods of how social media can be
used to disseminate research, guidance on how to develop a social media portfolio for consideration
of academic promotion, and some best practices for promoting one’s research work.
Corrosion Protection of Nano-biphasic Calcium Phosphate Coating on Titanium Substrate
Authors: Fathi Ahlam M. , Mandour Howida S. , Abd El-Hamid Hanaa K. 
Published: November 2019

Background:Increasing the bioactivity of metallic implants is necessary for biomaterial applications where hydroxyapatite (HA) is used as a surface coating. In industry, HA is currently coated by plasma spraying, but this technique has a high cost and produces coating with short-term stability.Objectives:In the present study, electrophoretic deposition (EPD) was used to deposit nano-biphasic calcium phosphate compound (β-tri-calcium phosphate (β-TCP) /hydroxyapatite (HA)) bio-ceramics on the titanium surface. The microstructural, chemical compositions and bioactivity of the β- TCP/HA coatings were studied in a simulated body fluid solution (SBF).Methods:Scanning electron microscopy (SEM) equipped with energy-dispersive X-ray spectroscopy (EDX) and Fourier transform infrared spectroscopy (FTIR) were used. Additionally, the antibacterial effect was studied by the agar diffusion method. The corrosion behavior of the β-TCP/HA coating on titanium surface (Ti) in the SBF solution at 37oC was investigated by means of electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization tests.Results:The Ti surface modification increased its biocompatibility and corrosion resistance in the simulated body fluid. The antibacterial inhibition activity of the β-TCP/HA bio-ceramic was enhanced by electroless silver deposition. The enhanced properties could be attributed to the use of nano-sized biphasic calcium phosphates in a low-temperature EPD process.Conclusions:The β-TCP/HA and β-TCP/HA/Ag coatings well protect Ti from the corrosion in SBF and endow Ti with biocompatibility. The β-4-TCP/HA/Ag/Ti substrate shows good antibacterial activity.
Prediction of Neddylation Sites Using the Composition of k-spaced Amino Acid Pairs and Fuzzy SVM
Authors: Ju Zhe , Wang Shi-Yun 
Published: November 2019

Introduction:
Neddylation is the process of ubiquitin-like protein NEDD8 attaching
substrate lysine via isopeptide bonds. As a highly dynamic and reversible post-translational
modification, lysine neddylation has been found to be involved in various biological processes and
closely associated with many diseases.

Objective:
The accurate identification of neddylation sites is necessary to elucidate the underlying
molecular mechanisms of neddylation. As traditional experimental methods are often expensive
and time-consuming, it is imperative to design computational methods to identify neddylation
sites.

Methods:
In this study, a novel predictor named CKSAAP_NeddSite is developed to detect
neddylation sites. An effective feature encoding technology, the composition of k-spaced amino
acid pairs, is used to encode neddylation sites. And the F-score feature selection method is adopted
to remove the redundant features. Moreover, a fuzzy support vector machine algorithm is
employed to overcome the class imbalance and noise problem.

Results:
As illustrated by 10-fold cross-validation, CKSAAP_NeddSite achieves an AUC of
0.9848. Independent tests also show that CKSAAP_NeddSite significantly outperforms existing
neddylation sites predictor. Therefore, CKSAAP_NeddSite can be a useful bioinformatics tool for
the prediction of neddylation sites. Feature analysis shows that some residues around neddylation
sites may play an important role in the prediction.

Conclusion:
The results of analysis and prediction could offer useful information for elucidating
the molecular mechanisms of neddylation. A user-friendly web-server for CKSAAP_NeddSite is
established at 123.206.31.171/CKSAAP_NeddSite.