bluuebunny/crossref_metadata_2025_split huggingface dataset:
The institutional turn in service research: taking stock and moving ahead
Authors: Koskela-Huotari Kaisa , Vink Josina , Edvardsson Bo 
Published: April 2020

Purpose
Service scholars are finding that institutions – enduring social structures, such as rules, norms, beliefs – are increasingly important in theorizing on service-related phenomena. The purpose of this paper is to advance the use of institutional theory in service research by synthesizing the key insights from institutional theory that have been applied to service-related phenomena and developing a research agenda to guide the future use of institutional theory in service research.

Design/methodology/approach
This paper is an integrative literature review covering 68 articles from major service research and marketing journals that adopt institutional concepts and frameworks to study service-related phenomena.

Findings
The paper maps the “institutional turn” of service research, that is, the increasing tendency to draw on institutional theory for theoretical insights within service research and builds a conceptual framework of the institutional stabilization and destabilization mechanisms that explain endurance and change in service phenomena. The paper also proposes a research agenda that outlines four previously ignored aspects of institutions that have important implications for service research.

Research limitations/implications
In addition to synthesizing insights and proposing directions for future research, the paper highlights specific theoretical and methodological considerations for the future use of institutional theory within service research. The literature review is limited to the 13 major service research and marketing journals.

Originality/value
This paper is the first literature review of the use of institutional theory in service research.
Oat beta glucans anti-inflammatory actions in leg exercise stress
Authors: Thompson Jennifer Creamer , Kirby Timothy , DiSilvestro Robert A. 
Published: April 2020

PurposeDietary fiber is not traditionally considered to have anti-inflammatory actions in skeletal muscle. This study aims to test the hypothesis that oat β-glucans fiber intake can inhibit exercise-induced inflammation.Design/methodology/approachYoung adult males (age 18-30 years) consumed either oat bran β-glucans (2 × 1.5 g fiber/day) or placebo for 4 weeks (Trial 1:N= 11 for placebo,N= 9 for glucan; Trial 2:N= 7 for placebo,N= 8 for glucan). Muscle inflammatory stress was induced at baseline and post-intervention using a leg extension regimen.FindingsIngestion of β-glucans, but not placebo, protected against inflammation based on subjective soreness scores (two trials), as well as on plasma myeloperoxidase readings (one trial). Scores were subject ratings from 0 (no soreness) to 10 (injury that impairs movement). Mean soreness score was lower at 48 h after exercise stress: post-glucan treatment vs pre-treatment: Trial 1: 1.9 + 2.4 vs 3.3 + 2.2 (p= 0.05); Trial 2: 1.2 + 0.7 vs 3.9 + 2.7 (p< 0.05). Myeloperoxidase just after exercise stress increased for both groups pre-treatment, but only for the placebo group post-treatment: 62 + 12 vs 81 + 15 (p< 0.05).Originality/valueThis pilot study found that at least one type of dietary fiber can exert anti-inflammatory effects in skeletal muscle.
Integrated reporting in higher education: insights from Scotland, Northern Ireland and Wales
Authors: Adhikariparajuli Mahalaximi , Hassan Abeer , Fletcher Mary , Elamer Ahmed A. 
Published: April 2020

PurposeThis paper aims to examine the level of disclosure on content elements of integrated reporting (IR) in Scotland, Northern Ireland and Wales higher education institutions (HEIs). The authors suggest that integrated thinking is an internal process that organizations can follow to increase the level of disclosure on IR that can be used as an effective mechanism to enhance accountability with stakeholders.Design/methodology/approachInternational Integrated Reporting Council (IIRC) guidelines and content analysis are used to analyze IR content elements in HEI reports from 2014-2016.FindingsThe results indicate a significant increase in the trend and extent of IR content elements. The HEI-specific characteristics examined, such as establishment of HEI; adoption of IR framework and governing board size are all statistically and positively associated with IR content elements disclosure. This paper introduces signalling theory to explore the idea that appropriate communication via integrated thinking can close the gap between the organization and its stakeholders via increased level of disclosure on IR content elements.Practical implicationsThe results will assist policymakers and regulators to assess the benefits of voluntary implementation of IR at HEIs and evaluate possible mandatory implementation of IIRC guidelines. Second, the findings can assist managers of institutions interested in implementing IR.Social implicationsThis study recommends universities to explicitly address IR issues in reporting, as this will increase their impact as leaders of educational thought in addition to their roles as partners, advisors, counselors and assessors.Originality/valueThis study explores whether HEIs in Scotland, Northern Ireland and Wales provide disclosure on IIRC content elements as a reflection of integrated thinking and whether the connectivity and interdependence between different departments will help to signal to stakeholders how HEIs create value for society.
A glimpse at growth hormone–releasing hormone cosmos
Authors: Barabutis Nektarios 
Published: April 2020

AbstractGrowth hormone–releasing hormone is a hypothalamic neuropeptide, which regulates the secretion of growth hormone by the anterior pituitary gland. Recent evidence suggest that it exerts growth factor activities in a diverse variety of in vivo and in vitro experimental malignancies, which are counteracted by growth hormone–releasing hormone antagonists. Those peptides support lung endothelial barrier integrity by suppressing major inflammatory pathways and by inducing the endothelial defender P53. The present effort provides information regarding the effects of growth hormone–releasing hormone in the regulation of P53 and the unfolded protein response. Furthermore, it suggests the possible application of growth hormone–releasing hormone antagonists towards the management of acute lung injury, including the lethal acute respiratory distress syndrome.
Physiological and genomic characterization of a new ‘Candidatus Nitrotoga’ isolate
Authors: Ishii Kento , Fujitani Hirotsugu , Sekiguchi Yuji , Tsuneda Satoshi 
Published: April 2020

SummaryOxidation of nitrite to nitrate is an important process in the global nitrogen cycle. Recent molecular biology‐based studies have revealed that the widespread nitrite‐oxidizing bacteria (NOB) belonging to the genus ‘Candidatus Nitrotoga’ may be highly important for the environment. However, the insufficient availability of pure Nitrotoga cultures has limited our understanding of their physiological and genomic characteristics. Here, we isolated the ‘Ca. Nitrotoga’ sp. strain AM1P, from a previously enriched Nitrotoga culture, using an improved isolation strategy. Although ‘Ca. Nitrotoga’ have been recognized as cold‐adapted NOB, the strain AM1P had a slightly higher optimum growth temperature at 23°C. Strain AM1P showed a pH optimum of 8.3 and was not inhibited even at high nitrite concentrations (20 mM). We obtained the complete genome of the strain and compared the genome profile to five previously sequenced ‘Ca. Nitrotoga’ strains. Comparative genomics suggested that lactate dehydrogenase may be only encoded in the strain AM1P and closely related genomes. While the growth yield of AM1P did not change, we observed faster growth in the presence of lactate in comparison to purely chemolithoautotrophic growth. The characterization of the new strain AM1P sheds light on the physiological adaptation of this environmentally important, but understudied genus ‘Ca. Nitrotoga’.
An Examination of Public Hospital Productivity and its Persistence: An Index Number Approach
Authors: Cheng Choon C. , Scott Anthony , Sundararajan Vijaya , Yan Wenda , Yong Jongsay 
Published: April 2020

AbstractThis paper measures the level and growth of total factor productivity (TFP) of public hospitals in Victoria, Australia, using an index number approach. We further examine the persistence of productivity over time, and the extent to which productivity varies with hospital characteristics such as hospital size. Hospital administrative data from Victoria from 2007–08 to 2011–12 are used. We find substantial variation in TFP across hospitals: large hospitals perform significantly better than small hospitals, both in TFP level and growth. Productivity level is highly persistent over time, but not productivity growth.
British terrorism preemption: Subjectivity and disjuncture in Channel “de‐radicalization” interventions
Authors: Pettinger Tom 
Published: April 2020

AbstractThis article examines Channel “de‐radicalization” interventions, which take place on individuals suspected of having the potential to commit terrorist crimes. Situated within critical security studies, the article explores the British Prevent programme by utilizing primary interviews with hard‐to‐reach Channel mentors and senior Prevent officials. Following the work of anticipatory risk‐governance scholarship, this research illuminates the three processes of risk‐visibilization (how an individual becomes sufficiently “seen” as harbouring risk that they are offered Channel mentorship), risk‐calculation (how practitioners negotiate supposed riskiness), and risk‐knowing (how practitioners “know” risks they observe). It demonstrates how the practice of preemptive counter‐terrorism is subsumed inherently by—even relies upon—subjectivity and human prejudice, and fundamental disagreements between practitioners. Through substantial empirical contribution on the phenomenon of Channel interventions, the discussion highlights ultimately that the algorithmic rationale of preemptive risk‐spotting normalizes the suspicion of banal and everyday behaviors, precisely because such interventions are ultimately deployed through worst‐case imaginations.
Pregnancy outcomes after a mass vaccination campaign with an oral cholera vaccine: a systematic review and meta‐analysis
Authors: Zhang Y , Zhang H , Wang B , Song G , Hayden JC , Amirthalingam P , Rahmani J , Bhagavathula AS , Li Z 
Published: April 2020

BackgroundCholera has harmful effects on the fetus but safety data on the oral cholera vaccine in pregnant women are controversial.ObjectivesWe conducted the first meta‐analysis of studies in pregnant women comparing the effect of oral cholera vaccination on pregnancy outcomes with unvaccinated women. Outcomes of interest were adverse pregnancy outcome, miscarriage, stillbirth, preterm delivery, low birthweight, abortion and malformation.Search strategyThe search was run in MEDLINE/PubMed, SCOPUS and Embase databases from inception up to December 2019.Selection criteriaInclusion criteria were: (1) studies that investigated the association between oral cholera vaccines and adverse pregnancy outcomes; (2) studies that reported outcomes with appropriate estimates; and (3) studies that contained an unvaccinated control group.Data collection and analysisA random‐effects model (DerSimonian and Laird) was run to evaluate the overall treatment effect (relative risk, RR). The PRISMA statement was followed in reporting this meta‐analysis.Main resultsFive studies included in meta‐analysis with 5584 women (2920 exposed and 2664 not exposed). No significant increase in adverse pregnancy outcome (RR 1.03, 95% CI 0.79–1.34), miscarriage (RR 1.15, 95% CI 0.84–1.57) or stillbirth (RR 1.11, 95% CI 0.69–1.80) following cholera vaccine administration was found compared with control group. There was also no association with an increased risk of preterm delivery (RR 0.61, 95% CI 0.35–1.06) low birthweight (RR 0.84, 95% CI 0.56– 1.26), accidental abortion (RR 1.02, 95% CI 0.77–1.35) or malformation (RR 0.70, 95% CI 0.22–2.25).ConclusionsThis study shows no evidence of an association between oral cholera vaccination and adverse pregnancy outcomes. The findings do not rigorously exclude the possibility that the vaccine protocol may result in some degree of harm.Tweetable abstractThere is no evidence of an association between oral cholera vaccination and adverse pregnancy outcomes. The findings do not rigorously exclude the possibility that the vaccine protocol may result in some degree of harm.
A cardiovascular disease risk prediction algorithm for use with the Medicare current beneficiary survey
Authors: Fouayzi Hassan , Ash Arlene S. , Rosen Amy K. 
Published: April 2020

AbstractObjectiveTo develop a cardiovascular disease (CVD) risk score that can be used to quantify CVD risk in the Medicare Current Beneficiary Survey (MCBS).Data SourcesWe used 1999‐2013 MCBS data.Study DesignWe used a backward stepwise approach and cox proportional hazards regressions to build and validate a new CVD risk score, similar to the Framingham Risk Score (FRS), using only information available in MCBS. To assess its performance, we calculated C statistics and examined calibration plots.Data Collection/Extraction MethodsWe studied 21 968 community‐dwelling Medicare beneficiaries aged 65 years or older without pre‐existing CVD. We obtained risk factors from both survey and claims data. We used claims data to derive “CVD event within 3 years” following the FRS definition of CVD.Principal FindingsAbout five percent of MCBS participants developed a CVD event over a mean follow‐up period of 348 days. Our final MCBS‐based model added morbidity burden, reported general health status, and functional limitation to the traditional FRS predictors of CVD. This model had relatively fair discrimination (C statistic = 0.69; 95% confidence interval [CI], 0.67‐0.71) and performed well on validation (C = 0.68; CI, 0.66‐0.70). More importantly, the plot of observed CVD outcomes versus predicted ones showed that this model had a good calibration.ConclusionsOur new CVD risk score can be calculated using MCBS data, thereby extending the survey's ability to quantify CVD risk in the Medicare population and better inform both health policy and health services research.
Effect of e‐cigarette advertisement themes on hypothetical e‐cigarette purchasing in price‐responsive adolescents
Authors: Barnes Andrew J. , Bono Rose S. , Rudy Alyssa K. , Hoetger Cosima , Nicksic Nicole E. , Cobb Caroline O. 
Published: April 2020

AbstractAimsTo examine the effect on adolescents of exposure to different e‐cigarette advertisement themes on reported likelihood of purchasing e‐cigarettes in a hypothetical scenario.DesignBetween‐subjects design of four randomly assigned thematic conditions derived from a content analysis of 350 e‐cigarette advertisements: general, flavor‐ and taste‐themed, people‐ and product use‐themed or control advertisements for bottled water.SettingVirginia, USA.ParticipantsOf 1360 adolescents (13–18 years old) participating, 1063 had complete data (519 current cigarette smokers, 544 tobacco‐susceptible non‐smokers).MeasurementsParticipants completed an e‐cigarette purchase task, reporting the likelihood of buying an e‐cigarette at various prices. Indices of abuse liability included price responsiveness (whether likelihood of purchase decreased with increasing prices) and, among price‐responsive adolescents, breakpoint (highest price before definitely would not buy), maximum probability‐weighted expenditure (Omax) and price elasticity (how quickly willingness to purchase decreases as prices increase). Regressions controlled for demographics, prior tobacco ad exposure, tobacco/substance use and sensation‐seeking.FindingsPrior advertisement exposure was positively associated with being price‐responsive [odds ratio (OR) = 1.12, 95% confidence interval (CI) = 1.03, 1.22; P < 0.05]. Among price‐responsive adolescents (n = 579), breakpoints were 58% higher in the flavor‐ and taste‐themed condition (β = 0.46, 95% CI = <0.01, 0.92) and 75% higher in the people‐ and product use‐themed condition (β = 0.56, 95% CI = 0.10, 1.03) compared with control (Ps < 0.05). Exposure to people‐ and product use‐themed advertisements was associated with a 60% higher Omax (β = 0.47, 95% CI = 0.01, 0.93; P < 0.05). The general and people‐ and product use‐themed conditions were associated with 19% (β = −0.21, 95% CI = –0.38, ‐0.04) and 21% (β = −0.24, 95% CI = –0.42, −0.06) lower elasticity, respectively (Ps < 0.05).ConclusionsE‐cigarette advertising exposure may increase reported likelihood of purchasing e‐cigarettes, with effects differing by advertisement content. People‐ and product use‐themed e‐cigarette advertisements increased reported likelihood of purchasing in price‐responsive adolescents.
Impacts of trade liberalization in Canada's supply managed dairy industry
Authors: Biden Scott , Ker Alan P. , Duff Stephen 
Published: April 2020

AbstractTrade is an integral part of the Canadian economy. The main institutional drivers governing trade are bilateral and multilateral agreements outlining permissible trade distorting measures. Since its inception in 1972, Canada's supply management system has remained protected throughout trade negotiations. The system appears, by any economic measure, to be having an increasingly disproportional influence in recent trade negotiations. However, trade agreements serve not only to maximize social surplus, but also to maximize some measure of political welfare. Canada has recently negotiated three prominent trade agreements: the Canada‐European Union Comprehensive Economic and Trade Agreement (CETA) came into effect in the latter part of 2017; the Comprehensive and Progressive Agreement for Trans‐Pacific Partnership (CPTPP) came into effect at the end of 2018; and the Canada‐United States‐Mexico Agreement (CUSMA) could come into effect in 2020. Collectively, these agreements have guaranteed increased market access for fresh and processed dairy products. We build a spatial partial equilibrium model of the Canadian dairy industry consisting of three regions and 10 commodities to assess the individual and cumulative effect of these trade agreements. We pay particular attention to the institutional drivers within today's dairy sector: milk protein isolates; component pricing, including Class 7; and differential demand growth. We find that the aggregate impacts are: (a) a 1.4% decrease in the marginal retail price; (b) a 4.8% decrease in the blended producer price; and (c) an overall increase in social welfare of 7.8%. Worth noting, the decrease in producer surplus varies from 0.7% in the western region to 1.5% in Ontario. Our results may be relevant to future negotiations as well as the publicly promised compensation package for dairy producers.
Psychosocial effects of appearance changes due to cancer treatment and needs for information and supportive care in Japanese cancer patients
Authors: Sakai Hitomi , Koyama Atsuko , Tanaka Kaoru , Watanabe Satomi , Nakura Miki , Yasuda Toshiko , Hayashi Makiko , Endo Miyuki , Nakagawa Kazuhiko 
Published: April 2020

AbstractPurposeCancer treatment can alter patient appearance, leading to psychological, social, and behavioral issues. This study aimed to investigate distress and difficulties related to appearance concerns in Japanese cancer patients and to identify information and support needs among them.MethodsWe conducted a questionnaire survey using the Derriford Appearance Scale 59 (DAS59) among cancer patients with a prior history of chemotherapy, molecular targeted therapy, or immunotherapy, who were recruited from the Departments of Medical Oncology and Psychosomatic Medicine, Kindai University Hospital.ResultsParticipants were 114 patients with a mean age of 62.9 years; 70.2% were female, 86.0% had metastatic or locally advanced unresectable cancer, and 78.1% had concerns about some aspect of their appearance. Mean DAS59 full‐scale score was 77.7 ± 36.4. Younger and female participants were found to have higher full‐scale scores in univariate analysis (P < .05 for both), and younger participants were found to have higher full‐scale scores in multivariate analysis (P < .05).ConclusionsDAS59 scores had a wide distribution, suggesting that psychological distress due to appearance changes showed large individual differences. Young and female patients tended to have high DAS59 full‐scale scores, but some older and male patients also had high scores. Basic information regarding appearance changes should be provided to all patients before initiating cancer treatment. Both information provision prior to treatment and care at the time of actual appearance changes are important, and should be handled through a multidisciplinary approach.
Nodular lichen myxoedematous: a new adverse event associated with ustekinumab
Authors: Montero‐Vilchez Trinidad , Martinez‐Lopez Antonio , Cuenca‐Barrales Carlos , Martin‐Castro Aurelio , Molina‐Leyva Alejandro , Arias‐Santiago Salvador 
Published: April 2020

AbstractNodular lichen myxoedematosus is a localised form of lichen myxoedematosus, a chronic idiopathic cutaneous mucinosis of known aetiology. Ustekinumab is a human interleukin‐12/23 monoclonal antibody that could directly or indirectly increase mucin production. Herein, we report for the first time a case of nodular lichen myxoedematosus associated with ustekinumab.
Effect of ursodeoxycholic acid on liver markers: A systematic review and meta‐analysis of randomized placebo‐controlled clinical trials
Authors: Simental‐Mendía Mario , Sánchez‐García Adriana , Simental‐Mendía Luis E. 
Published: April 2020

AimThe objective of this meta‐analysis was to evaluate the effect of ursodeoxycholic acid (UDCA) therapy on serum liver function tests.MethodsPubMed, Web of Science, Scopus and Google Scholar databases were searched to identify randomized placebo‐controlled trials assessing the impact of UDCA on hepatic parameters. Meta‐analysis was conducted using a random‐effects model and sensitivity analysis through the leave‐one‐out method in the Review Manager statistical software version 5.3.ResultsAfter UDCA treatment, meta‐analysis revealed a significant reduction of alanine aminotransferase (weighted mean difference [WMD]: –15.28 U/L, 95% confidence interval [CI]: −23.42, −7.15, P = 0.0002, I2 = 97%), aspartate aminotransferase (WMD: –16.13 U/L, 95% CI: −23.84, −8.42, P < 0.0001, I2 = 97%), gamma‐glutamyl transferase (WMD: –23.29 U/L, 95% CI: −33.97, −12.61, P < 0.0001, I2 = 97%), alkaline phosphatase (WMD: –93.80 U/L, 95% CI: −126.36, −61.25, P < 0.0001, I2 = 95%) and bilirubin (WMD: –0.18 U/L, 95% CI: −0.35, −0.01, P = 0.04, I2 = 93%), but not significant changes in albumin levels (WMD: 0.10 U/L, 95% CI: −0.05, 0.24, P = 0.18, I2 = 80%).ConclusionThe results of the present meta‐analysis suggest a hepatoprotective effect of UDCA by reducing serum liver parameters.