bluuebunny/crossref_metadata_2025_split huggingface dataset:
FinTech revolution: the impact of management information systems upon relative firm value and risk
Authors: Mitra Sovan , Karathanasopoulos Andreas 
Published: October 2020

AbstractThe FinTech or ‘financial technology’ revolution has been gaining increasing interest as technologies are fundamentally changing the business of financial services. Consequently, financial technology is playing an increasingly important role in providing relative performance growth to firms. It is also well known that such relative performance can be observed through pairs trading investment. Therefore pairs trading have implications for understanding financial technology performance, yet the relationships between relative firm value and financial technology are not well understood. In this paper we investigate the impact of financial technology upon relative firm value in the banking sector. Firstly, using pairs trade data we show that financial technologies reveal differences in relative operational performance of firms, providing insight on the value of financial technologies. Secondly, we find that contribution of relative firm value growth from financial technologies is dependent on the specific business characteristics of the technology, such as the business application and activity type. Finally, we show that financial technologies impact the operational risk of firms and so firms need to take into account both the value and risk benefits in implementing new technological innovations. This paper will be of interest to academics and industry professionals.
Review of microwave techniques used in the manufacture and fault detection of aircraft composites
Authors: Li Z. , Wang P. , Haigh A. , Soutis C. , Gibson A. 
Published: October 2020

ABSTRACTMicrowaves are a form of electromagnetic radiation commonly used for telecommunications, navigation and food processing. More recently microwave technologies have found applications in fibre-reinforced polymer composites, which are increasingly used in aircraft structures. Microwave energy can be applied with low power (up to milliwatts) for non-destructive testing and high power (up to kilowatts) for heating/curing purposes. The state-of-the-art applications at high power include curing, three-dimensional (3D) printing, joining and recycling, whereas low-power microwave techniques can provide quality checks, strain sensing and damage inspection. Low-power microwave testing has the advantage of being non-contact, there is no need for surface transducers or couplants, it is operator friendly and relatively inexpensive; high-power microwave energy can offer volumetric heating, reduced processing time and energy saving with no ionising hazards. In this paper the recent research progress is reviewed, identifying achievements and challenges. First, the critical electromagnetic properties of composites that are closely related to the heating and sensing performance are discussed. Then, representative case studies are presented. Finally, the trends are outlined, including intelligent/automated inspection and solid-state heating.
“The Show Is Not about Race’”: Custom, Screen Culture, and the Black and White Minstrel Show
Authors: Grandy Christine 
Published: October 2020

AbstractIn 1967, when the BBC was faced with a petition by the Campaign Against Racial Discrimination requesting an end to the televised variety program the Black and White Minstrel Show (1958–1978), producers at the BBC, the press, and audience members collectively argued that the historic presence of minstrelsy in Britain rendered the practice of blacking up harmless. This article uses critical race theory as a useful framework for unpacking defenses that hinged on both the color blindness of white British audiences and the simultaneous existence of wider customs of blacking up within British television and film. I examine a range of “screen culture” from the 1920s to the 1970s, including feature films, home movies, newsreels, and television, that provide evidence of the existence of blackface as a type of racialized custom in British entertainment throughout this period. Efforts by organizations such as the Campaign Against Racial Discrimination, black press publications like Flamingo, and audiences of color to name blacking up and minstrelsy as racist in the late 1960s were met by fierce resistance from majority white audiences and producers, who denied their authority to do so. Concepts of color blindness or “racial innocence” thus become a useful means of examining, first, the wide-ranging existence of blacking-up practices within British screen culture; second, a broad reluctance by producers and the majority of audiences to identify this as racist; and third, the exceptional role that race played in characterizations of white audiences that were otherwise seen as historically fragile and impressionable in the face of screen content.
Limited Liberties: Catholics and the Policies of the Pitt Ministry in an Early Modern Context
Authors: Sanderson Mary Louise 
Published: October 2020

AbstractThis article contributes to current debates about the role of religion in governance in the late eighteenth century British Atlantic world by examining the Pitt ministry's policies regarding Catholic subjects in England, Quebec, and Ireland in an early modern context. Starting with an overview of early modern attempts to find a compromise between Catholic subjects and their Protestant rulers, this article shows how the Pitt ministry reused these earlier approaches in its efforts to respond to Catholic subjects during of the age of revolution. Focusing on the English Catholic Relief Act of 1791, the Canada Constitutional Act, and the ministry's unimplemented plans for Catholic emancipation, the article argues that these policies were all shaped in part around the idea that Catholic subjects could be allowed greater freedoms, and even access to political influence in some cases, if their faith was contained through Gallican-style restrictions. These restrictions varied from requiring new oaths to attempting to establish the government's right to select Catholic bishops. Each policy resulted in notably different outcomes based on the location and potential power of the Catholic subjects that they affected. The common goal, however, was to attenuate the Catholics’ connection to the papacy and increase government influence over the Catholic Church in British territory while also upholding the ultimate supremacy of the Anglican Church.
Surgical anatomy of the lymphatic drainage of the salivary glands: a systematic review
Authors: Abou-Foul A K 
Published: October 2020

AbstractBackgroundNodal metastasis in salivary gland malignancies has important clinical implications; a good understanding of their complex anatomy is paramount to the head and neck surgeon.MethodsA contemporary and comprehensive literature review was conducted of the lymphatic drainage of the salivary glands, with special emphasis on its surgical applications.ResultsThe parotid gland has extraglandular and intraglandular nodes acting as a single functional drainage unit. Intraglandular parotid notes are unique to the parotid gland, and consist of a larger superficial group and a smaller deep group. The presence of intraglandular submandibular nodes, as described by early anatomists, is much debated nowadays. The sublingual glands drain to the lingual lymph nodes, which are divided into median, intermediate and lateral groups.ConclusionThis review highlights the complex arrangements of lymph nodes draining the salivary glands. It may provide a valid anatomical explanation for the nodal metastasis patterns commonly seen in salivary gland malignancy.
CPC Algorithm: Exact Area Coverage by a Mobile Robot Using Approximate Cellular Decomposition
Authors: Guruprasad K. R. , Ranjitha T. D. 
Published: October 2020

SUMMARYA new coverage path planning (CPP) algorithm, namely cell permeability-based coverage (CPC) algorithm, is proposed in this paper. Unlike the most CPP algorithms using approximate cellular decomposition, the proposed algorithm achieves exact coverage with lower coverage overlap compared to that with the existing algorithms. Apart from a formal analysis of the algorithm, the performance of the proposed algorithm is compared with two representative approximate cellular decomposition-based coverage algorithms reported in the literature. Results of demonstrative experiments on a TurtleBot mobile robot within the robot operating system/Gazebo environment and on a Fire Bird V robot are also provided.
Orange juice intake and anthropometric changes in children and adolescents
Authors: Sakaki Junichi R , Li Jing , Melough Melissa M , Ha Kyungho , Tamimi Rulla M , Chavarro Jorge E , Chen Ming-Hui , Chun Ock K 
Published: October 2020

AbstractObjective:Evaluate associations between orange juice (OJ) consumption and anthropometric parameters.Design:Prospective cohort study assessing the association between OJ intake and changes in BMI and height-for-ageZ-score (HAZ) using mixed linear regression.Setting:2004–2008, USA.Participants:Children from the Growing Up Today Study II (n7301), aged 9–16 years at enrollment.Results:OJ consumption was positively associated with 2-year change in HAZ in girls (mean (se)): 0·03 (0·01) for non-consumers, 0·03 (0·02) for 1–3 glasses/month, 0·06 (0·01) for 1–6 glasses/week and 0·09 (0·02) for ≥1 glass/d after full adjustment (Ptrend= 0·02). However, OJ consumption was not associated with 2-year change in BMI percentile (kg/m2, mean (se)): –0·44 (0·36) for non-consumers, 0·20 (0·41) for 1–3 glasses/month, –0·04 (0·34) for 1–6 glasses/week and –0·77 (0·62) for ≥1 glass/d in girls,Ptrend= 0·81; –0·94 (0·53) for non-consumers, –1·68 (0·52) for 1–3 glasses/month, –0·81 (0·38) for 1–6 glasses per week and –1·12 (0·61) for ≥1 glass/d in boys,Ptrend= 0·49.Conclusion:OJ consumption was favourably associated with height growth but unrelated to excess weight gain. OJ may be a useful alternative to whole fruit in the event that whole fruit intake is insufficient.
Laboratory Soft X-Ray Microscopy with an Integrated Visible-Light Microscope—Correlative Workflow for Faster 3D Cell Imaging
Authors: Dehlinger Aurélie , Seim Christian , Stiel Holger , Twamley Shailey , Ludwig Antje , Kördel Mikael , Grötzsch Daniel , Rehbein Stefan , Kanngießer Birgit 
Published: October 2020

Abstract
Interactive Text Graph Mining with a Prolog-Based Dialog Engine
Authors: TARAU PAUL , BLANCO EDUARDO 
Published: October 2020

AbstractOn top of a neural network-based dependency parser and a graph-based natural language processing module, we design a Prolog-based dialog engine that explores interactively a ranked fact database extracted from a text document. We reorganize dependency graphs to focus on the most relevant content elements of a sentence and integrate sentence identifiers as graph nodes. Additionally, after ranking the graph, we take advantage of the implicit semantic information that dependency links and WordNet bring in the form of subject–verb–object, “is-a” and “part-of” relations. Working on the Prolog facts and their inferred consequences, the dialog engine specializes the text graph with respect to a query and reveals interactively the document’s most relevant content elements. The open-source code of the integrated system is available at https://github.com/ptarau/DeepRank.
Maternal resistance to diet-induced obesity partially protects newborn and post-weaning male mice offspring from metabolic disturbances
Authors: Simino Laís Angélica de Paula , Panzarin Carolina , Torsoni Marcio Alberto , Ignácio-Souza Letícia Martins , Milanski Marciane , Torsoni Adriana Souza 
Published: October 2020

AbstractThe rising rate of childhood overweight follows the increase in maternal obesity, since perinatal events impact offspring in a diversity of metabolic disorders. Despite many studies that have linked dietary consumption, overnutrition, or maternal obesity as the mediators of fetal metabolic programming, there are gaps regarding the knowledge about the contribution of different maternal phenotypes to the development of metabolic disturbances in offspring. This study aimed to investigate whether maternal high-fat diet (HFD) consumption without the development of the obese phenotype would protect offspring from metabolic disturbances. Female mice were fed standard chow diet or a HFD for 4 weeks before mating. HFD females were classified into obesity-resistant (OR) or obesity-prone (OP), according to weight gain. OP females presented with higher adiposity, fasting serum glucose and insulin, cholesterol and non-esterified fatty acid (NEFA). Newborn offspring from OP dams showed higher serum glucose and insulin and alteration in hepatic gene expression that may have contributed to the rise in hepatic fat content and decline of glycogen levels in the liver. Despite offspring from OR and OP females having showed similar growth after the day of delivery, offspring from OP females had higher caloric intake, fasting glucose, serum triglycerides and altered hepatic gene expression, as well as glucose and pyruvate intolerance and lower insulin sensitivity at d28 compared with offspring from OR females. Maternal pre-pregnancy serum glucose, insulin, and NEFA positively correlated with serum glucose and fat liver content and negatively correlated with hepatic glycogen in offspring. In conclusion, our results show that maternal resistance to diet-induced obesity partially protects offspring from early metabolic disturbances.
Origin of Weakened Interannual Sea Surface Temperature Variability in the Southeastern Tropical Atlantic Ocean
Authors: Prigent Arthur , Imbol Koungue Rodrigue Anicet , Lübbecke Joke F. , Brandt Peter , Latif Mojib 
Published: October 2020

AbstractObservations and reanalysis products are used to investigate the substantial weakening in the southeastern tropical Atlantic sea surface temperature (SST) variability since 2000. Relative to 1982–1999, the March‐April‐May SST variability in the Angola‐Benguela area (ABA) has decreased by more than 30%. Both equatorial remote forcing and local forcing are known to play an important role in driving SST variability in the ABA. Compared to 1982–1999, since 2000, equatorial remote forcing had less influence on ABA SSTs, whereas local forcing has become more important. In particular, the robust correlation that existed between the equatorial zonal wind stress and the ABA SSTs has substantially weakened, suggesting less influence of Kelvin waves on ABA SSTs. Moreover, the strong correlation linking the South Atlantic Anticyclone and the ABA SSTs has reduced. Finally, multidecadal surface warming of the ABA could also have played a role in the weakening of the interannual SST variability.
The Emission of Terrestrial Gamma Ray Flashes From Encountering Streamer Coronae Associated to the Breakdown of Lightning Leaders
Authors: Köhn C. , Heumesser M. , Chanrion O. , Nishikawa K. , Reglero V. , Neubert T. 
Published: October 2020

AbstractTerrestrial gamma ray flashes (TGFs) are beams of high‐energy photons associated to lightning. These photons are the bremsstrahlung of energetic electrons whose origin is currently explained by two mechanisms: energizing electrons in weak, but large‐scale thundercloud fields or the acceleration of low‐energy electrons in strong, but localized fields of lightning leaders. Contemporary measurements by the Atmosphere‐Space Interactions Monitor suggest that the production of TGFs is related to the leader step and associated streamer coronae when upward moving intracloud lightning illuminates. Based on these observations, we apply a particle‐in‐cell Monte Carlo code tracing electrons in the superposed electric field of two encountering streamer coronae and modeling the subsequent photon emission. We also perform a parameter study by solving the deterministic equations of motion for one electron. We find that this mechanism can explain the occurrence of TGFs with photons energies of several MeV lasting for tens to hundreds of μs, in agreement with observations.
Lower Hybrid Waves at the Magnetosheath Separatrix Region
Authors: Tang B.‐B. , Li W. Y. , Graham D. B. , Wang C. , Khotyaintsev Yu. V. , Le A. , Giles B. L. , Lindqvist P.‐A. , Ergun R. E. , Burch J. L. 
Published: October 2020

AbstractLower hybrid waves are investigated at the magnetosheath separatrix region in asymmetric guide field reconnection by using the Magnetospheric Multiscale (MMS) mission. Three of the four MMS spacecraft observe clear wave activities around the lower hybrid frequency across the magnetosheath separatrix, where a density gradient is present. The observed waves are consistent with generation by the lower hybrid drift instability. The characteristic properties of these waves include the following: (1) the waves propagate toward the x‐line in the spacecraft frame due to the large out‐of‐plane magnetic field, which is in the same direction of the diamagnetic drift of the x‐line; (2) the wave potential is about 20% of the electron temperature. These drift waves effectively produce cross‐field particle diffusion, enabling the transport of magnetosheath electrons into the exhaust region. At last, we suggest that the lower hybrid waves at the magnetosheath separatrix region represent some unique features of asymmetric guide field reconnection, which is different from that widely observed at the magnetospheric side of magnetopause reconnection.
NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential
Authors: Xie Na , Zhang Lu , Gao Wei , Huang Canhua , Huber Peter Ernst , Zhou Xiaobo , Li Changlong , Shen Guobo , Zou Bingwen 
Published: October 2020

AbstractNicotinamide adenine dinucleotide (NAD+) and its metabolites function as critical regulators to maintain physiologic processes, enabling the plastic cells to adapt to environmental changes including nutrient perturbation, genotoxic factors, circadian disorder, infection, inflammation and xenobiotics. These effects are mainly achieved by the driving effect of NAD+ on metabolic pathways as enzyme cofactors transferring hydrogen in oxidation-reduction reactions. Besides, multiple NAD+-dependent enzymes are involved in physiology either by post-synthesis chemical modification of DNA, RNA and proteins, or releasing second messenger cyclic ADP-ribose (cADPR) and NAADP+. Prolonged disequilibrium of NAD+ metabolism disturbs the physiological functions, resulting in diseases including metabolic diseases, cancer, aging and neurodegeneration disorder. In this review, we summarize recent advances in our understanding of the molecular mechanisms of NAD+-regulated physiological responses to stresses, the contribution of NAD+ deficiency to various diseases via manipulating cellular communication networks and the potential new avenues for therapeutic intervention.
Emerging role of tumor cell plasticity in modifying therapeutic response
Authors: Qin Siyuan , Jiang Jingwen , Lu Yi , Nice Edouard C. , Huang Canhua , Zhang Jian , He Weifeng 
Published: October 2020

AbstractResistance to cancer therapy is a major barrier to cancer management. Conventional views have proposed that acquisition of resistance may result from genetic mutations. However, accumulating evidence implicates a key role of non-mutational resistance mechanisms underlying drug tolerance, the latter of which is the focus that will be discussed here. Such non-mutational processes are largely driven by tumor cell plasticity, which renders tumor cells insusceptible to the drug-targeted pathway, thereby facilitating the tumor cell survival and growth. The concept of tumor cell plasticity highlights the significance of re-activation of developmental programs that are closely correlated with epithelial–mesenchymal transition, acquisition properties of cancer stem cells, and trans-differentiation potential during drug exposure. From observations in various cancers, this concept provides an opportunity for investigating the nature of anticancer drug resistance. Over the years, our understanding of the emerging role of phenotype switching in modifying therapeutic response has considerably increased. This expanded knowledge of tumor cell plasticity contributes to developing novel therapeutic strategies or combination therapy regimens using available anticancer drugs, which are likely to improve patient outcomes in clinical practice.
CircRNA_09505 aggravates inflammation and joint damage in collagen-induced arthritis mice via miR-6089/AKT1/NF-κB axis
Authors: Yang Jinghan , Cheng Min , Gu Bingjie , Wang Jinghua , Yan Shushan , Xu Donghua 
Published: October 2020

AbstractA number of circular RNAs (circRNAs) have been implicated in rheumatoid arthritis (RA) pathogenesis; however, little is known about their function and hidden molecular mechanism in immune and inflammation regulation. We investigated the role and the underlying mechanism of circRNA_09505 in RA in this study. Real-time PCR and fluorescence in situ hybridization (FISH) are adopted to estimate the quantitative expression and localization of circRNA_09505 in macrophages. The altering effect of circRNA_09505 on inflammation is investigated in vitro and in vivo by use of macrophage cell models and collagen-induced arthritis (CIA) mice. Luciferase reporter assay and RNA-binding protein immunoprecipitation (RIP) are used to confirm the circRNA_09505/miR-6089 ceRNA network predicted by bioinformatics analysis. Compared with controls, the expression of circRNA_09505 is upregulated in peripheral blood mononuclear cells (PBMCs) from patients with RA. The proliferation and cell cycle are significantly promoted when circRNA_09505 is upregulated in macrophages, whereas knockdown of circRNA_09505 inhibits macrophage proliferation and cell- cycle progression. Besides, circRNA_09505 can act as a miRNA sponge for miR-6089 in macrophages, and promote the production of TNF-α, IL-6, and IL-12 through ceRNA mechanism. Moreover, AKT1 is a direct target of miR-6089. CircRNA_09505 can promote AKT1 expression by acting as a miR-6089 sponge via IκBα/NF-κB signaling pathway in macrophages. Most interestingly, knockdown of circRNA_09505 significantly alleviates arthritis and inflammation in vivo in CIA mice. These data support the hypothesis that circRNA_09505 can function as a miR-6089 sponge and regulate inflammation via miR-6089/AKT1/NF-κB axis in CIA mice.
A deep learning approach to programmable RNA switches
Authors: Angenent-Mari Nicolaas M. , Garruss Alexander S. , Soenksen Luis R. , Church George , Collins James J. 
Published: October 2020

AbstractEngineered RNA elements are programmable tools capable of detecting small molecules, proteins, and nucleic acids. Predicting the behavior of these synthetic biology components remains a challenge, a situation that could be addressed through enhanced pattern recognition from deep learning. Here, we investigate Deep Neural Networks (DNN) to predict toehold switch function as a canonical riboswitch model in synthetic biology. To facilitate DNN training, we synthesize and characterize in vivo a dataset of 91,534 toehold switches spanning 23 viral genomes and 906 human transcription factors. DNNs trained on nucleotide sequences outperform (R2 = 0.43–0.70) previous state-of-the-art thermodynamic and kinetic models (R2 = 0.04–0.15) and allow for human-understandable attention-visualizations (VIS4Map) to identify success and failure modes. This work shows that deep learning approaches can be used for functionality predictions and insight generation in RNA synthetic biology.