bluuebunny/crossref_metadata_2025_split huggingface dataset:
An advanced meta-learner based on artificial electric field algorithm optimized stacking ensemble techniques for enhancing prediction accuracy of soil shear strength
Authors: Cao Minh-Tu , Hoang Nhat-Duc , Nhu Viet Ha , Bui Dieu Tien 
Published: November 2020

AbstractShear strength is a crucial property of soils regarded as its intrinsic capacity to resist failure when forces act on the soil mass. This study proposes an advanced meta-leaner to discern the shear strength property and generate a reliable estimation of the ultimate shear strength of the soil. The proposed model is named as metaheuristic-optimized meta-ensemble learning model (MOMEM) and aims at helping geotechnical engineers accurately predict the parameter of interest. The MOMEM was established with the integration of the artificial electric field algorithm (AEFA) to dynamically blend the radial basis function neural network (RBFNN) and multivariate adaptive regression splines (MARS). In the framework of forming MOMEM, the AEFA consistently monitor the learning phases of the RBFNN and MARS in mining soil shear strength property through optimizing their controlling parameters, including neuron number, Gaussian spread, regularization coefficient, and kernel function parameter. Simultaneously, RBFNN and MARS are stacked via a linear combination method with dynamic weights optimized by the AEFA metaheuristic. The one-tailttest on 20 running times affirmed that with the greatest mean and standard deviation of RMSE (mean = 0.035 kg/cm2; Std. = 0.005 kg/cm2), MAE (mean = 0.026 kg/cm2; Std. = 0.004 kg/cm2), MAPE (mean = 7.9%; Std. = 1.72%), andR2(mean = 0.826; Std. = 0.055), the MOMEM is significantly superior to other artificial intelligence-based methods. These analytical results indicate that MOMEM is an innovative tool for accurate calculating soil shear strength; thus, it provides geotechnical engineers with reliable figures to significantly increase soil-related engineering design.
Neurological updates: neurological complications of CAR-T therapy
Authors: Tallantyre Emma C. , Evans Nia A. , Parry-Jones Jack , Morgan Matt P. G. , Jones Ceri H. , Ingram Wendy 
Published: November 2020

AbstractChimeric antigen receptor (CAR)-expressing T cells now offer an effective treatment option for people with previously refractory B cell malignancies and are under development for a wide range of other tumours. However, neurological toxicity is a common complication of CAR-T cell therapy, seen in over 50% of recipients in some cohorts. Since 2018, the term immune effector cell-associated neurotoxicity syndrome (ICANS) has been used to describe and grade neurotoxicity seen after CAR-T cells and other similar therapies. ICANS following CAR-T therapy is usually self-limiting but can necessitate admission to the intensive care unit and is rarely fatal. As CAR-T therapies enter routine clinical practice, it is important for neurologists to be aware of the nature of neurological complications. Here, we summarise the clinical manifestations, mechanisms, investigations and recommended treatment of CAR-T-related neurotoxicity, focusing on the licensed CD19 products.
Impact of the COVID-19 pandemic on an interdisciplinary endoscopy unit in a German “hotspot” area: a single center experience
Authors: Wichmann Dörte , Atique Naushad Bijoy , Stüker Dietmar , Fusco Stefano , Schempf Ulrike , Grottenthaler Julia M. , Böckeler Michael , Thiel Christian , Zender Lars , Königsrainer Alfred , Malek Nisar P. , Werner Christoph R. 
Published: November 2020

Abstract
Background and study aims
Since December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), has posed a pandemic threat to global health and has challenged health care system in all affected countries.

Patients and methods
This is a combined study including a descriptive part about the changes in the daily work routine of an Interdisciplinary Endoscopic Unit (IEU) and a prospective analysis of patients tested positive for SARS-CoV-2 who required endoscopic interventions. Conclusively, we present the finding of a point-prevalence analysis in the staff of the IEU.

Results
We present effects of the COVID-19-related restructuring of processes in our interdisciplinary endoscopy unit (IEU) with respect to cancelation of examinations, relocation of staff to other departments, impact of SARS-CoV-2 on medical staff of the IEU, and supply of protective clothing. Additionally, we analyzed the cohort of COVID-19 patients: Sixteen endoscopic interventions were done in ten patients. In all patients with confirmed infection with SARS-CoV-2, emergency endoscopies were required for relevant bleeding situations. Re-endoscopies were required only in critically ill COVID-19 patients.

Conclusions
The restructuring of processes in the IEU was feasible in short time, effective, and can also be applied broadly at least in developed countries [Garbe et al. in Gastroenterology 159:778–780, 2020; Repici A, Pace F, Gabbiadini R, Colombo M, Hassan C, Dinelli M, Group IG-CW, Maselli R, Spadaccini M, Mutignani M, Gabbrielli A, Signorelli C, Spada C, Leoni P, Fabbri C, Segato S, Gaffuri N, Mangiavillano B, Radaelli F, Salerno R, Bargiggia S, Maroni L, Benedetti A, Occhipinti P, De Grazia F, Ferraris L, Cengia G, Greco S, Alvisi C, Scarcelli A, De Luca L, Cereatti F, Testoni PA, Mingotto R, Aragona G, Manes G, Beretta P, Amvrosiadis G, Cennamo V, Lella F, Missale G, Lagoussis P, Triossi O, Giovanardi M, De Roberto G, Cantu P, Buscarini E, Anderloni A, Carrara S, Fugazza A, Galtieri PA, Pellegatta G, Antonelli G, Rosch T, Sharma P (2020) Endoscopy units and the COVID-19 Outbreak: a Multi-Center Experience from Italy. Gastroenterology;]. The endoscopy-related rate of SARS-CoV-2 infection of staff is low, but supply of protective equipment is crucial for this. Endoscopic procedures in COVID-19 patients were not directly related to SARS-CoV-2 infection, but to other underlying diseases or typical complications of long-term ICU treatment.
Synthesis and characterization of PLGA/HAP scaffolds with DNA-functionalised calcium phosphate nanoparticles for bone tissue engineering
Authors: Sokolova Viktoriya , Kostka Kathrin , Shalumon K. T. , Prymak Oleg , Chen Jyh-Ping , Epple Matthias 
Published: November 2020

AbstractPorous scaffolds of poly(lactide-co-glycolide) (PLGA; 85:15) and nano-hydroxyapatite (nHAP) were prepared by an emulsion-precipitation procedure from uniform PLGA–nHAP spheres (150–250 µm diameter). These spheres were then thermally sintered at 83 °C to porous scaffolds that can serve for bone tissue engineering or for bone substitution. The base materials PLGA and nHAP and the PLGA–nHAP scaffolds were extensively characterized by X-ray powder diffraction, infrared spectroscopy, thermogravimetry, differential scanning calorimetry, and scanning electron microscopy. The scaffold porosity was about 50 vol% as determined by relating mass and volume of the scaffolds, together with the computed density of the solid phase (PLGA–nHAP). The cultivation of HeLa cells demonstrated their high cytocompatibility. In combination with DNA-loaded calcium phosphate nanoparticles, they showed a good activity of gene transfection with enhanced green fluorescent protein (EGFP) as model protein. This is expected enhance bone growth around an implanted scaffold or inside a scaffold for tissue engineering.
A priori error estimates for a linearized fracture control problem
Authors: Mohammadi Masoumeh , Wollner Winnifried 
Published: November 2020

AbstractA control problem for a linearized time-discrete regularized fracture propagation process is considered. The discretization of the problem is done using a conforming finite element method. In contrast to many works on discretization of PDE constrained optimization problems, the particular setting has to cope with the fact that the linearized fracture equation is not necessarily coercive. A quasi-best approximation result will be shown in the case of an invertible, though not necessarily coercive, linearized fracture equation. Based on this a priori error estimates for the control, state, and adjoint variables will be derived.
High-Value, Cost-Conscious Care Attitudes in the Graduate Medical Education Learning Environment: Various Stakeholder Attitudes That Residents Misjudge
Authors: Mordang Serge B. R. , Leep Hunderfund Andrea N. , Smeenk Frank W. J. M. , Stassen Laurents P. S. , Könings Karen D. 
Published: November 2020

Abstract
Background
Training residents in delivering high-value, cost-conscious care (HVCCC) is crucial for a sustainable healthcare. A supportive learning environment is key. Yet, stakeholders’ attitudes toward HVCCC in residents’ learning environment are unknown.

Objective
We aimed to measure stakeholders’ HVCCC attitudes in residents’ learning environment, compare these with resident perceptions of their attitudes, and identify factors associated with attitudinal differences among each stakeholder group.

Design
We conducted a cross-sectional survey across the Netherlands between June 2017 and December 2018.

Participants
Participants were 312 residents, 305 faculty members, 53 administrators, and 1049 patients from 66 (non)academic hospitals.

Main Measures
Respondents completed the Maastricht HVCCC Attitude Questionnaire (MHAQ), containing three subscales: (1) high-value care, (2) cost incorporation, (3) perceived drawbacks. Additionally, resident respondents estimated the HVCCC attitudes of other stakeholders, and answered questions on job demands and resources. Univariate and multivariate analyses were used to analyze data.

Key Results
Attitudes differed on all subscales: faculty and administrators reported more positive HVCCC attitudes than residents (p ≤ 0.05), while the attitudes of patients were less positive (p ≤ 0.05). Residents underestimated faculty’s (p < 0.001) and overestimated patients’ HVCCC attitudes (p < 0.001). Increasing age was, among residents and faculty, associated with more positive attitudes toward HVCCC (p ≤ 0.05). Lower perceived health quality was associated with less positive attitudes among patients (p < 0.001). The more autonomy residents perceived, the more positive their HVCCC attitude (p ≤ 0.05).

Conclusions
Attitudes toward HVCCC vary among stakeholders in the residency learning environment, and residents misjudge the attitudes of both faculty and patients. Faculty and administrators might improve their support to residents by more explicitly sharing their thoughts and knowledge on HVCCC and granting residents autonomy in clinical practice.
Genetic Divergence Across Glacial Refugia Despite Interglacial Gene Flow in a Crested Newt
Authors: Wielstra Ben , Salvi Daniele , Canestrelli Daniele 
Published: November 2020

AbstractMtDNA-based phylogeography has illuminated the impact of the Pleistocene Ice Age on species distribution dynamics and the build-up of genetic divergence. The well-known shortcomings of mtDNA in biogeographical inference can be compensated by integrating multilocus data and species distribution modelling into phylogeography. We re-visit the phylogeography of the Italian crested newt (Triturus carnifex), a species distributed in two of Europe’s main glacial refugia, the Balkan and Italian Peninsulas. While a new 51 nuclear DNA marker dataset supports the existence of three lineages previously suggested by mtDNA (Balkan, northern Italy and southern Italy), the nuclear DNA dataset also provides improved resolution where these lineages have obtained secondary contact. We observe geographically restricted admixture at the contact between the Balkan and northern Italy gene pools and identify a potential mtDNA ghost lineage here. At the contact between the northern and southern Italy gene pools we find admixture over a broader area, as well as asymmetric mtDNA introgression. Our species distribution model is in agreement with a distribution restricted to distinct refugia during Pleistocene glacial cycles and postglacial expansion with secondary contact. Our study supports: (1) the relevance of the north-western Balkan Peninsula as a discrete glacial refugium; (2) the importance of north-eastern Italy and the northern Apennine as suture zones; and (3) the applicability of a refugia-within-refugia scenario within the Italian Peninsula.
Cor triatriatum sinister with left anomalous pulmonary venous drainage to innominate vein: what to do with the vertical vein?
Authors: Ishiwari Keiichi , Nomura Koji , Ko Yoshihiro , Hamaya Izumi , Momoki Kodai , Takagi Tomomitsu 
Published: November 2020

AbstractWe treated a surgical case of a 47-day-old male infant diagnosed with an unusual type of cor triatriatum sinister (CTS) with left anomalous pulmonary venous drainage to the innominate vein via a vertical vein. After preoperative hemodynamic assessment of pulmonary venous (PV) return, this patient underwent a resection of the fibromuscular membrane between the accessory and the true left atrial chambers, concomitant with vertical vein banding to facilitate a left PV return through a common pulmonary venous collector (CPVC). Catheterization three months after this surgery revealed no obstruction of the PV return to the mitral orifice as well as good growth of the CPVC as a left PV return pathway. The patient has been doing well on aspirin.
Assessment of wear micromechanisms on a laser textured cemented carbide tool during abrasive-like machining by FIB/FESEM
Authors: Fang Shiqi , Bähre Dirk , Llanes Luis 
Published: November 2020

AbstractThe combined use of focused ion beam (FIB) milling and field-emission scanning electron microscopy inspection (FESEM) is a unique and successful approach for assessment of near-surface phenomena at specific and selected locations. In this study, a FIB/FESEM dual-beam platform was implemented to docment and analyze the wear micromechanisms on a laser-surface textured (LST) hardmetal (HM) tool. In particular, changes in surface and microstructural integrity of the laser-sculptured pyramids (effective cutting microfeatures) were characterized after testing the LST-HM tool against a steel workpiece in a workbench designed to simulate an external honing process. It was demonstrated that: (1) laser-surface texturing does not degrade the intrinsic surface integrity and tool effectiveness of HM pyramids; and (2) there exists a correlation between the wear and loading of shaped pyramids at the local level. Hence, the enhanced performance of the laser-textured tool should consider the pyramid geometry aspects rather than the microstructure assemblage of the HM grade used, at least for attempted abrasive applications.
Ternary MOF-Based Redox Active Sites Enabled 3D-on-2D Nanoarchitectured Battery-Type Electrodes for High-Energy-Density Supercapatteries
Authors: Nagaraju Goli , Sekhar S. Chandra , Ramulu Bhimanaboina , Hussain Sk. Khaja , Narsimulu D. , Yu Jae Su 
Published: November 2020

Abstract
Designing rationally combined metal–organic frameworks (MOFs) with multifunctional nanogeometries is of significant research interest to enable the electrochemical properties in advanced energy storage devices. Herein, we explored a new class of binder-free dual-layered Ni–Co–Mn-based MOFs (NCM-based MOFs) with three-dimensional (3D)-on-2D nanoarchitectures through a polarity-induced solution-phase method for high-performance supercapatteries. The hierarchical NCM-based MOFs having grown on nickel foam exhibit a battery-type charge storage mechanism with superior areal capacity (1311.4 μAh cm−2 at 5 mA cm−2), good rate capability (61.8%; 811.67 μAh cm−2 at 50 mA cm−2), and an excellent cycling durability. The superior charge storage properties are ascribed to the synergistic features, higher accessible active sites of dual-layered nanogeometries, and exalted redox chemistry of multi metallic guest species, respectively. The bilayered NCM-based MOFs are further employed as a battery-type electrode for the fabrication of supercapattery paradigm with biomass-derived nitrogen/oxygen doped porous carbon as a negative electrode, which demonstrates excellent capacity of 1.6 mAh cm−2 along with high energy and power densities of 1.21 mWh cm−2 and 32.49 mW cm−2, respectively. Following, the MOF-based supercapattery was further assembled with a renewable solar power harvester to use as a self-charging station for various portable electronic applications.
REDUNET: reducing test suites by integrating set cover and network-based optimization
Authors: Mongiovì Misael , Fornaia Andrea , Tramontana Emiliano 
Published: November 2020

Abstract
The availability of effective test suites is critical for the development and maintenance of reliable software systems. To increase test effectiveness, software developers tend to employ larger and larger test suites. The recent availability of software tools for automatic test generation makes building large test suites affordable, therefore contributing to accelerating this trend. However, large test suites, though more effective, are resources and time consuming and therefore cannot be executed frequently. Reducing them without decreasing code coverage is a needed compromise between efficiency and effectiveness of the test, hence enabling a more regular check of the software under development. We propose a novel approach, namely REDUNET, to reduce a test suite while keeping the same code coverage. We integrate this approach in a complete framework for the automatic generation of efficient and effective test suites, which includes test suite generation, code coverage analysis, and test suite reduction. Our approach formulates the test suite reduction as a set cover problem and applies integer linear programming and a network-based optimisation, which takes advantage of the properties of the control flow graph. We find the optimal set of test cases that keeps the same code coverage in fractions of seconds on real software projects and test suites generated automatically by Randoop. The results on ten real software systems show that the proposed approach finds the optimal minimisation and achieves up to 90% reduction and more than 50% reduction on all systems under analysis. On the largest project our reduction algorithm performs more than three times faster than both integer linear programming alone and the state-of-the-art heuristic Harrold Gupta Soffa.
Die S3-Leitlinie „Peri- und Postmenopause – Diagnostik und Interventionen“ – eine Zusammenfassung
Authors:   Schweizerische Menopause Gesellschaft (SMG), Stute Petra 
Published: November 2020

Zusammenfassung2020 wurde die S3-Leitlinie „Peri- und Postmenopause – Diagnostik und Interventionen“ publiziert, an deren Erarbeitung zwei Mandatsträger aus der Schweiz beteiligt waren. Der Artikel gibt eine Übersicht zu den Statements und Empfehlungen zu verschiedenen Aspekten der Hormonersatztherapie. Indikationen für eine Hormonersatztherapie sind nach wie vor das klimakterische Syndrom und die Prävention der Osteoporose.
Microplastic fiber and drought effects on plants and soil are only slightly modified by arbuscular mycorrhizal fungi
Authors: Lehmann Anika , Leifheit Eva F. , Feng Linshan , Bergmann Joana , Wulf Anja , Rillig Matthias C. 
Published: November 2020

AbstractMicroplastics are increasingly recognized as a factor of global change. By altering soil inherent properties and processes, ripple-on effects on plants and their symbionts can be expected. Additionally, interactions with other factors of global change, such as drought, can influence the effect of microplastics. We designed a greenhouse study to examine effects of polyester microfibers, arbuscular mycorrhizal (AM) fungi and drought on plant, microbial and soil responses. We found that polyester microfibers increased the aboveground biomass of Allium cepa under well-watered and drought conditions, but under drought conditions the AM fungal-only treatment reached the highest biomass. Colonization with AM fungi increased under microfiber contamination, however, plant biomass did not increase when both AM fungi and fibers were present. The mean weight diameter of soil aggregates increased with AM fungal inoculation overall but decreased when the system was contaminated with microfibers or drought stressed. Our study adds additional support to the mounting evidence that microplastic fibers in soil can affect the plant-soil system by promoting plant growth, and favoring key root symbionts, AM fungi. Although soil aggregation is usually positively influenced by plant roots and AM fungi, and microplastic promotes both, our results show that plastic still had a negative effect on soil aggregates. Even though there are concerns that microplastic might interact with other factors of global change, our study revealed no such effect for drought.
Influence of the Precursor and the Temperature of Synthesis on the Structure of Saponite
Authors: Meyer Sebastian , Bennici Simona , Vaulot Cyril , Rigolet Séverinne , Dzene Liva 
Published: November 2020

AbstractSeveral procedures for hydrothermal synthesis of saponite can be found in the literature. They differ in terms of the preparation conditions of the precursor and of the synthesis temperature. The objective of the present study was to investigate how these two parameters influence the structure of the final synthesis product. The precursor was prepared from Mg(NO3)2, Al(NO3)3, and Na4SiO4 in three different ways: as a gel, a dried gel, and a calcined gel. The influence of the synthesis temperature on the structure of saponite was investigated in the range 90–200°C. The results showed that the use of a calcined precursor yielded a single mineral phase, saponite, with up to 90% aluminum in tetrahedral configuration. In comparison, the use of a gel precursor resulted in a product with only 60% aluminum in the tetrahedral configuration. The synthesis temperature had no significant effect on the saponite structure. The reported synthesis method showed the possibility of obtaining saponite with superior characteristics, in terms of crystallinity, surface acidity, and thermal stability compared to the natural mineral, even at 90°C, and thus with greater potential for industrial application.
Liberate our Library: doing decolonisation work at Goldsmiths Library
Authors: Clarke Marilyn 
Published: November 2020

Library work now has a role to play when it comes to decolonisation. This article outlines what Goldsmiths Library, University of London is doing, through theLiberate our Libraryinitiative, to diversify and decolonise its collections and practices against the backdrop of worldwide movements for education and social justice led by both students and academics to challenge the dominance of the ‘Westernised university’.2Examples of how we are doing this work are explained using critical librarianship as our guide, whilst recognising that we are still developing expertise in this evolving field of practice. This decolonisation work also uses critical race theory (CRT) as a means to dismantle racial inequality and its impact on higher education.Here, I would like to acknowledge the excellent and inspirational content ofALJ, Critical Librarianship: Special Issue (v.44, no.2) and I see this article as an ongoing companion piece.Goldsmiths Library's liberation work endeavours to empower its users with critical thinking and study skills whilst conducting their research using hierarchical systems and resources which in themselves are in the process of being decolonised.Decolonising a library collection and a profession must of course always begin or at least happen in tandem with the self, through a process that Kenyan author Ngũgĩ wa Thiong'o describes as ‘decolonising the mind.’3