bluuebunny/crossref_metadata_2025_split huggingface dataset:
Professions today: self-criticism and reflections for the future
Authors: Sarfatti Larson Magali 
Published: August 2020

This article revisits my 1977 work The Rise of Professionalism, outlining what I now believe was wrong in my book and what I think may still be useful in order to move on to some ideas about the present situation. One of the predominant questions is whether we should completely merge the study of professions with that of knowledge-based occupations. And if we accept that the age of experts has entirely supplanted the former public life of trustee professions, what consequences derive? What trends will future research need to consider? These tentative and incomplete ideas should be read as calls for further research.
Implicados, intermitentes, desengajados? Estilos de mediação de pais de crianças de 3-8 anos que usam a internet
Authors: Ponte Cristina , Simões José Alberto , Batista Susana , Castro Teresa Sofia 
Published: August 2020

Este artigo apresenta resultados do primeiro inquérito nacional sobre como crianças (3-8 anos) se relacionam com ecrãs em ambientes familiares, focando-se nas mediações de pais cujos filhos fazem uso da internet. Com base em literatura sobre o tema e em resultados sobre o contexto português, procedeu-se a análises estatísticas de correspondências múltiplas e de clusters que consideraram fatores do lado da criança e do lado dos pais relativamente a mediações ativas e de segurança. Da análise emergiram três tipos de mediadores — implicados, intermitentes e desengajados — cujas características se discutem e se problematizam.
Time Series Predictive Models for Social Networking Media Usage Data: The Pragmatics and Projections
Authors: Jayaram M. A. , Jayatheertha Gayitri , Rajpurohit Ritu 
Published: August 2020

Aims: We have set forth three main objectives in the work presented in this paper, they are namely, to study how social networking media usage is surging over the time for three social media networks viz., Facebook, Twitter and LinkedIn, ii.to develop best fitting time series predictive models for predicting future usage of three network media and, iii. to make a comparative analysis to herald the ups and downs noticed in the usage across three network media considered.
Study Design: Application of time series techniques for the analysis of social network user’s data. The main research question addressed by this work is to see how time series models augurs for time dependent data such as the one chosen in this research.
Place and Duration of Study: Research Center, Department of Master of Computer Applications, Siddaganga Institute of Technology, Tumakuru, Karnataka, India, between January 2020- April 2020.
Methodology: The work delved on collection three social network users (Facebook, LinkedIn, and Twitter) data for a span of nine years i.e., for the tenure 2011-2019. One dimensional, two dimensional and three dimensional visual analytics is made prior to time series analysis. Time series predictive analytics involved development of best fits for prediction. To select the best fits among linear, polynomial, exponential, power function and logarithmic models, mean absolute error and root mean square error metrics were used.
Results: Linear, polynomial function trend lines proved to be the best for Facebook, LinkedIn and Twitter respectively with low values of MAE and RMSE and high values of regression coefficients as compared with other kinds of models. Apart from the error metrics, the Theil’s U-statistic values of 0.928, 1.008 and 1.21 for Facebook, Twitter and LinkedIn also heralded the fact that these functions are superior models when compared with other naïve models. It is also projected that by 2025, Facebook will see 10,000 billion, followed by LinkedIn at 1500 billion while Twitter would see 750 billion people if same kind of surge trend prevails in user numbers across three networks considered in this research.
Conclusion: This paper presented a unique work which is supposedly deemed to be the first of its kind to the best of the knowledge of authors. The models come with a limitation that, they can provide accurate projection if the same trend prevails in the pattern of upheavals in usage.
The utility of the Psychopathy Checklist‐Revised (PCL‐R) facet and item scores in predicting violent recidivism
Authors: Sohn Ji Seun , Raine Adrian , Lee Soo Jung 
Published: August 2020

AbstractThere is relatively limited research on psychopathy in non‐Caucasian ethnic groups and even less on the utility of the Psychopathy Checklist‐Revised (PCL‐R) that focuses on PCL‐R facet and item scores in predicting violent recidivism. In this study, we assessed the utility of the PCL‐R in prospectively predicting violent versus nonviolent recidivism during an 11‐year follow‐up window. A high‐risk sample of 451 incarcerated Korean male offenders was assessed on the PCL‐R at baseline. A total of 445 were reconvicted after release (353 violent and 92 nonviolent recidivists). Psychopathy facet scores were higher in violent compared to nonviolent recidivists. Facet 2 (affective) showed the strongest effect size (Cohen's d = 0.53; Percentage change in odds = 22.6%) in predicting violent recidivism. Analyses of the four items constituting the affective facet indicated that callous/lack of empathy (Percentage change in odds = 134.4%) and failure to accept responsibility (Percentage change in odds = 94.5%) were the strongest predictors of violent recidivism. Findings are to our knowledge the first to document the utility of the PCL‐R in distinguishing violent from nonviolent recidivism and highlight the role of affective impairment (particularly lack of empathy) in violent recidivism.
Systematic optimization of ultrasound grayscale imaging presets and its application in abdominal scanning
Authors: Long Zaiyang , Zhou Wei , Tradup Donald J. , Stekel Scott F. , Callstrom Matthew R. , Hangiandreou Nicholas J. 
Published: August 2020

AbstractPurposeUltrasound grayscale imaging preset optimization has often been qualitative and dependent upon vendor application specialists. This study aimed to propose a systematic approach for grayscale imaging preset optimization and apply the approach in a clinical abdominal scan setting.MethodsA six‐step approach was detailed including identification of clinical task, adjustment of basic parameters, fine‐tuning of advanced parameters, image performance metrics confirmation, clinical evaluation and data analysis, and implementation of new presets and monitoring of clinical usage. Its application in an abdominal scanning task was described for each step with phantoms, volunteers, and software tools.ResultsClinical image data analytics facilitated the understanding of the imaging task, relevant transducers, and target characteristics, in addition to specific requests from radiologists. Quantitative measurements were made on global image contrast and gray map function. In addition, clinically relevant phantoms and volunteer scans without and with acoustic distortion layers were involved to determine the new presets. Furthermore, phantom signal to noise ratio study and clinical evaluation using volunteers with different body habitus were utilized to confirm the superiority of the new presets. Quantitative clinical usage monitoring demonstrated successful implementation of the new presets.ConclusionsA systematic approach for grayscale imaging preset optimization has been proposed and successfully applied for a specific clinical task. This approach was designed to be generalizable and relatively flexible, which would facilitate movement away from previous qualitative and subjective approaches.
3D‐Printed Nerve Conduits with Live Platelets for Effective Peripheral Nerve Repair
Authors: Tao Jie , Liu Haofan , Wu Wenbi , Zhang Jiumeng , Liu Sijia , Zhang Jing , Huang Yulan , Xu Xin , He Hongchen , Yang Siming , Gou Maling 
Published: August 2020

AbstractPlatelets can secrete multiple growth factors for peripheral nerve repair. However, topically injected platelets are rapidly activated followed by burst release of the cargos, causing limited therapeutic efficiency in vivo. Herein, a platelet‐incorporated hydrogel conduit is shown that acts as a biosynthetic nerve conduit for peripheral nerve repair. This conduit is prepared by rapid 3D printing of the live platelets mixed with bio‐ink containing gelatin methacrylate (GelMA) and poly(ethyleneglycol)diacrylate (PEGDA). The hydrogel can significantly prolong the survival of the incorporated platelets. While the conduit provides a physical foundation for bridging the nerve gaps, live platelets in the conduit sustained‐release multiple growth factors to promote the nerve repair. The in vivo therapeutic efficiency of this platelet‐incorporated nerve conduit is tested in bridging a 10 mm gap in sciatic nerves. The results of morphological, electrophysiological, and histological assessments indicate that the incorporated platelets can significantly promote the hydrogel conduits in peripheral nerve repair. The demonstrated 3D bioprinted nerve conduit with live platelets may show potential clinical application in peripheral nerve repair.
Multiphoton Absorption Stimulated Metal Chalcogenide Quantum Dot Solar Cells under Ambient and Concentrated Irradiance
Authors: Hou Bo , Kim Byung‐Sung , Lee Harrison Ka Hin , Cho Yuljae , Giraud Paul , Liu Mengxia , Zhang Jingchao , Davies Matthew L. , Durrant James R. , Tsoi Wing Chung , Li Zhe , Dimitrov Stoichko D. , Sohn Jung Inn , Cha SeungNam , Kim Jong Min 
Published: August 2020

AbstractColloidal metal chalcogenide quantum dots (QDs) have excellent quantum efficiency in light–matter interactions and good device stability. However, QDs have been brought to the forefront as viable building blocks in bottom‐up assembling semiconductor devices, the development of QD solar cell (QDSC) is still confronting considerable challenges compared to other QD technologies due to their low performance under natural sunlight, as a consequence of untapped potential from their quantized density‐of‐state and inorganic natures. This report is designed to address this long‐standing challenge by accessing the feasibility of using QDSC for indoor and concentration PV (CPV) applications. This work finds that above bandgap photon energy irradiation of QD solids can generate high densities of excitons via multi‐photon absorption (MPA), and these excitons are not limited to diffuse by Auger recombination up to 1.5 × 1019 cm−3 densities. Based on these findings, a 19.5% (2000 lux indoor light) and an 11.6% efficiency (1.5 Suns) have been facilely realized from ordinary QDSCs (9.55% under 1 Sun). To further illustrate the potential of the MPA in QDSCs, 21.29% efficiency polymer lens CPVs (4.08 Suns) and viable sensor networks powered by indoor QDSCs matrix have been demonstrated.
Direct Observation of Interfacial Mechanical Failure in Thiophosphate Solid Electrolytes with Operando X‐Ray Tomography
Authors: Madsen Kenneth E. , Bassett Kimberly L. , Ta Kim , Sforzo Brandon A. , Matusik Katarzyna E. , Kastengren Alan L. , Gewirth Andrew A. 
Published: August 2020

AbstractHerein, the mechanical behaviors of Li10GeP2S12 (LGPS) solid electrolytes during electrochemical cycling using operando X‐ray tomography are investigated. It is demonstrated that the bulk mechanical decomposition of LGPS when cycled against lithium is a direct result of electrochemical reduction of the solid electrolyte at the LGPS/Li0 interface. The reductive decomposition of LGPS during lithium plating results in the formation of low‐density domains at the electrode/electrolyte interface, which impose sufficient mechanical stress on the underlying LGPS to crack the SE pellet. The critical stress developed prior to pellet fracture is significantly lower than the bulk shear modulus of LGPS, suggesting that the electrochemical instability of LGPS dramatically worsens the mechanical stability of the material near the LGPS/Li0 interface. It is also shown that the application of a highly concentrated liquid electrolyte to the LGPS surface suppresses the reductive decomposition of LGPS, improving both the electrochemical performance and mechanical stability of the bulk LGPS solid electrolyte.
Confining Ultrathin 2D Superlattices in Mesoporous Hollow Spheres Renders Ultrafast and High‐Capacity Na‐Ion Storage
Authors: Xia Qingbing , Liang Yaru , Lin Zeheng , Wang Shiwen , Lai Weihong , Yuan Ding , Dou Yuhai , Gu Qinfen , Wang Jia‐Zhao , Liu Hua Kun , Dou Shi Xue , Fang Shaoming , Chou Shu‐Lei 
Published: August 2020

AbstractSodium‐ion batteries have attracted ever‐increasing attention in view of the natural abundance of sodium resources. Sluggish sodiation kinetics, nevertheless, remain a tough challenge, in terms of achieving high rate capability and high energy density. Herein, a sheet‐in‐sphere nanoconfiguration of 2D titania–carbon superlattices vertically aligned inside of mesoporous TiO2@C hollow nanospheres is constructed. In such a design, the ultrathin 2D superlattices consist of ordered alternating monolayers of titania and carbon, enabling interpenetrating pathways for rapid transport of electrons and Na+ ions as well as a 2D heterointerface for Na+ storage. Kinetics analysis discloses that the combination of 2D heterointerface and mesoporosity results an intercalation pseudocapacitive charge storage mechanism, which triggers ultrafast sodiation kinetics. In situ transmission electron microscope imaging and in situ synchrotron X‐ray diffraction techniques elucidate that the sheet‐in‐sphere architecture can maintain robust mechanical and crystallographic structural stability, resulting an extraordinary high rate capability, remarkable stable cycling with a low capacity fading ratio of 0.04% per cycle over 500 cycles at 0.2 C, and exceptionally long‐term cyclability up to 20 000 cycles at 50 C. This study offers a method for the realization of a high power density and long‐term cyclability battery by designing of a hierarchical nanoarchitecture.
Survival analysis of farm bankruptcy filings: Evaluating the time to completion of chapter 12 bankruptcy cases
Authors: Dinterman Robert , Katchova Ani L. 
Published: August 2020

AbstractWe examine trends in bankruptcy completion times and financial characteristics for farmers filing for chapter 12 bankruptcy after it became a permanent fixture in bankruptcy law to assess justifications for the recently enacted Family Farmer Bankruptcy Clarification Act of 2017 and Family Farmer Relief Act of 2019. Since 2007, chapter 12 filers have seen noticeable increases in their debt levels whereas alternative business bankruptcies have either stagnated or declined in their debt. Using survival analysis methods to correct for the censored nature of open cases, we find that the average time to completion has consistently been longer for chapter 12 than the comparable chapters (7, 11, and 13) of business bankruptcies. Although chapter 12 completion times have not been increasing over time, we find that chapter 7 and 11 completion times have been declining over time for comparable businesses and that debt levels are a significant factor in increased completion times. Our results are consistent with claims that farmers have had rising debt levels in comparison to similar businesses filing for bankruptcy and provide evidence that farmers with increasing debt have had a more difficult time restructuring through chapter 12. EconLit citations: G33, K35, Q14, Q18.
Deeply Rooted: Maximizing the Strengths of a Historically Black University and Community‐based Participatory Research to Understand Environmental Stressors and Trauma among Black Youth
Authors: Mance GiShawn A. , Rodgers Caryn R.R. , Roberts Debra , Terry Amanda 
Published: August 2020

AbstractThis paper explores a partnership between an HBCU (Historically Black Colleges and Universities) and a community to understand trauma given the high rates of reported violence among youth locally. The accumulative stress of living in high‐stress, high‐poverty environments coupled with the normative developmental tasks of adolescence is thought to place these youths at risk for negative mental and physical outcomes (Murry et al., 2011). The current research uses a community‐based participatory research (CBPR) approach and developmental lens to better understand environmental stressors and subsequent trauma among Black youth. Specifically, the paper describes the recruitment, engagement, and equitable partnership between a youth advisory board (YAB), university research team, and community agencies advisory board (CAB). The current work is part of a larger research study designed to explore environmental stressors, coping, and social supports for Black youth residing in low‐resource urban communities. The broad objective of the research is to develop a trauma‐informed community intervention to improve adolescent mental health. The initial phase of this university–community research, which entails the YAB, CAB, and university discussion groups, is outlined in this paper. Community engagement and trust are key factors described in the literature when collaborating with communities of color. These themes were reiterated by research partners in this study. The research team created coding terms to identify themes from YAB and CAB transcript data, respectively. YAB themes regarding stressors centered around financial strain, anger, and loss/violence. CAB themes regarding adolescent mental health and resources centered around trauma, trust, and sustainability. Initial steps to utilize the themes identified thus far are described. The unique advantages of an HBCU and CBPR to address mental health disparities in ethnic minority communities are also highlighted.
An additional case of Néstor‐Guillermo progeria syndrome diagnosed in early childhood
Authors: Fisher Heather G. , Patni Nivedita , Scheuerle Angela E. 
Published: August 2020

AbstractNéstor‐Guillermo progeria syndrome (NGPS; OMIM 614008) is characterized by early onset and slow progression of symptoms including poor growth, lipoatrophy, pseudosenile facial appearance, and normal cognitive development. In contrast to other progeria syndromes, NGPS is associated with a longer lifespan and higher risk for developing severe skeletal abnormalities. It is an autosomal recessive condition caused by biallelic pathogenic variants in BANF1. There are two previously reported patients with NGPS, both Spanish with molecular diagnoses made in adulthood and having the same homozygous pathogenic variant c.34G > A; p.Ala12Thr. Presented here is a 2 year, 8 month old girl with short stature, poor weight gain, sparse hair, and dysmorphic facial features reminiscent of premature aging. Whole exome sequencing identified the same c.34G > A homozygous pathogenic variant in BANF1 as reported in the previous patients. This is the first reported case of a child and is supporting evidence for this recurrent loss of function variant.
The genetic landscape of inherited eye disorders in 74 consecutive families from the United Arab Emirates
Authors: Méjécase Cécile , Kozak Igor , Moosajee Mariya 
Published: August 2020

AbstractGenetic eye diseases are phenotypically and genetically heterogeneous, affecting 1 in 1,000 people worldwide. This prevalence can increase in populations where endogamy is a social preference, such as in Arab populations. A retrospective consecutive cohort of 91 patients from 74 unrelated families affected with non‐syndromic and syndromic inherited eye disease presenting to the ocular genetics service at Moorfields Eye Hospitals United Arab Emirates (UAE) between 2017 and 2019, underwent clinically accredited genetic testing using targeted gene panels. The mean ± SD age of probands was 27.4 ± 16.2 years, and 45% were female (41/91). The UAE has a diverse and dynamic population, and the main ethnicity of families in this cohort was 74% Arab (n = 55), 8% Indian (n = 6) and 7% Pakistani (n = 5). Fifty‐six families (90.3%) were genetically solved, with 69 disease‐causing variants in 40 genes. Fourteen novel variants were detected with large deletions in CDHR1 and TTLL5, a multiexon (1–8) duplication in TEAD1 and 11 single nucleotides variants in 9 further genes. ABCA4‐retinopathy was the most frequent cause accounting for 21% of cases, with the confirmed UAE founder mutation c.5882G>A p.(Gly1961Glu)/c.2570T>C p.(Leu857Pro) in 25%. High diagnostic yield for UAE patients can guide prognosis, family decision‐making, access to clinical trials and approved treatments.
Implementation of a registry and open access genetic testing program for inherited retinal diseases within a non‐profit foundation
Authors: Mansfield Brian C. , Yerxa Benjamin R. , Branham Kari H. 
Published: August 2020

AbstractThe Foundation Fighting Blindness is a 50‐year old 501c(3) non‐profit organization dedicated to supporting the development of treatments and cures for people affected by the inherited retinal diseases (IRD), a group of clinical diagnoses that include orphan diseases such as retinitis pigmentosa, Usher syndrome, and Stargardt disease, among others. Over $760 M has been raised and invested in preclinical and clinical research and resources. Key resources include a multi‐national clinical consortium, an international patient registry with over 15,700 members that is expanding rapidly, and an open access genetic testing program that provides no cost comprehensive genetic testing to people clinically diagnosed with an IRD living in the United States. These programs are described with particular focus on the challenges and outcomes of establishing the registry and genetic testing program.
A General Strategy for Hollow Metal‐Phytate Coordination Complex Micropolyhedra Enabled by Cation Exchange
Authors: Chen Meiling , Peng Chenxi , Su Yaoquan , Chen Xue , Zhang Yuezhou , Wang Yu , Peng Juanjuan , Sun Qiang , Liu Xiaowang , Huang Wei 
Published: August 2020

AbstractThe ability to incorporate functional metal ions (Mn+) into metal–organic coordination complexes adds remarkable flexibility in the synthesis of multifunctional organic–inorganic hybrid materials with tailorable electronic, optical, and magnetic properties. We report the cation‐exchanged synthesis of a diverse range of hollow Mn+‐phytate (PA) micropolyhedra via the use of hollow Co2+‐PA polyhedral networks as templates at room temperature. The attributes of the incoming Mn+, namely Lewis acidity and ionic radius, control the exchange of the parent Co2+ions and the degree of morphological deformation of the resulting hollow micropolyhedra. New functions can be obtained for both completely and partially exchanged products, as supported by the observation of Ln3+(Ln3+=Tb3+, Eu3+, and Sm3+) luminescence from as‐prepared hollow Ln3+‐PA micropolyhedra after surface modification with dipicolinic acid as an antenna. Moreover, Fe3+‐ and Mn2+‐PA polyhedral complexes were employed as magnetic contrast agents.
Hydroxamic Acids Immobilized on Resins (HAIRs): Synthese von Dual‐Target‐HDAC‐Inhibitoren und HDAC‐PROTACs
Authors: Sinatra Laura , Bandolik Jan J. , Roatsch Martin , Sönnichsen Melf , Schoeder Clara T. , Hamacher Alexandra , Schöler Andrea , Borkhardt Arndt , Meiler Jens , Bhatia Sanil , Kassack Matthias U. , Hansen Finn K. 
Published: August 2020

AbstractMulti‐Target‐Wirkstoffe stellen in der modernen Tumortherapie einen vielversprechenden Ansatz dar. Basierend auf dem bekannten Synergismus zwischen Histon‐Deacetylase‐Inhibitoren (HDACi) und alkylierenden Zytostatika präsentieren wir in dieser Arbeit die Entwicklung von alkylierenden HDACi, welche aus einer Pharmakophor‐Verknüpfungsstrategie hervorgegangen sind. Für die Synthese haben wir ein Protokoll entwickelt, bei dem Hydroxamsäuren an Festphasenharze immobilisiert und als vielseitig anwendbare Bausteine für die Synthese von funktionalisierten HDACi verwendet wurden. Verbindung 3 n zeigt eine signifikant bessere Induktion der Apoptose, Caspase‐3/7‐Aktivierung und Erzeugung von DNA‐Schäden als die Summe der biologischen Aktivitäten der einzelnen Pharmakophore. Um die Vielseitigkeit unserer beladenen Harze zu demonstrieren, wurde dieses Konzept auf die Synthese eines HDAC‐PROTAC 4 übertragen. Western‐Blot‐Experimente bestätigten, dass PROTAC 4 den Abbau von HDACs effizient induziert.