bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treating for stability: an ethnographic study of aspirations and limitations in haemophilia treatment in Europe
Authors: Hughes Thomas , Brok-Kristensen Mikkel , Gargeya Yosha , Worsøe Lottrup Anne Mette , Bo Larsen Ask , Torres-Ortuño Ana , Mackett Nicki , Stevens John 
Published: December 2020

Abstract

Background
Recent improvements in approaches to treatment have opened a window of opportunity to redefine and expand the goals of treatment in haemophilia This article explores treatment culture in light of these improvements and its potential impact on the range of possibilitis in the lived experience of haemophilia.

Aims
The aim of this article is to further investigate findings related to how health care professionals (HCPs) approach haemophilia treatment and care, one of the main themes identified in an ethnographic study of the everyday life of people with haemophilia (PwH). This large-scale study investigated PwH's beliefs and experiences related to their condition, their treatment, and their personal ways of managing the condition.

Methods
The study used ethnographic research methods. Five haemophilia experts helped frame the research design by providing historical and disease area context prior to the initation of field research. In the field, study researchers collected data through 8–12 hours of participant observation, semi-structured interviews, written exercises, facilitated group dialogues, and on-site observations of the interactions of PwH with friends, family, and HCPs. Study researchers also conducted on-site observation at haemophilia treatment centres (HTCs) and interviewed HCPs. The study employed a multi-tiered grounded theory approach and combined data were analysed using techniques such as inductive and deductive analysis, cross-case analysis, challenge mapping, and clustering exercises. This article explores findings related specifically to how HCPs approach haemophilia treatment and care, and is thus focused on a subset of the data from the study.

Results
Fifty-one PwH in Italy, Germany, Spain, UK, and Ireland were interviewed and followed in their daily lives. Eighteen HCPs from seven HTCs were interviewed, and on-site observation was undertaken at six of the HTCs. Most haematologists in the study ‘treated for stability’, rather than to guide PwH to overcome limitations. ‘Treating for stability’ here refers to an approach to haemophilia care that focuses on measuring success in terms of annual bleed rate, instilling a focus on mitigating risk, rather than an approach that allows PwH to overcome the limitations they face due to their condition. However, some haematologists had moved beyond treating for stability to instead treat for possibilities, enabling a better quality of life for PwH.

Conclusions
These results suggest that a culture of ‘treating for stability’ could be limiting progress in expanding the goals of treatment in haemophilia. Expanded metrics of success, more flexible approaches to treatment, and higher ambitions on behalf of PwH may be needed in treatment and care, in order for PwH to fully benefit from treatment advances and to increase their quality of life.
Improved Techniques for Uniaxial and Multiaxial Vibration Test Profile Definition
Authors: Kersch Kurthan , Wagner Andreas , Kuttner Thomas , Woschke Elmar 
Published: December 2020

Abstract
This work aims to improve profile derivation methods for uniaxial and multiaxial vibration testing. Thereby, the focus is put on the inclusion and processing of phase information between the excitation axes. An inherent necessity is the availability of field data. Two existing methods are independently extended by additional phase information and an appropriate processing. The first method is the Fatigue Damage Spectrum for a uniaxial profile derivation. The second method is the enveloping technique for a multiaxial profile derivation. Both methods are theoretically discussed and then evaluated with a fatigue damage calculation of an exemplary structure.
U progu dymisji. Wojewoda poleski Jan Krahelski wobec sytuacji na Polesiu w 1932 r
Authors: Cichoracki Piotr , Dufrat Joanna 
Published: December 2020

<p>Na 1932 r. przypadło w II Rzeczypospolitej Polskiej apogeum tzw. wielkiego kryzysu gospodarczego. Odbił się on zwłaszcza na położeniu mieszkańców wsi, także tej zdominowanej przez mniejszości narodowe w województwach wschodnich. Jednym z takich regionów było Polesie. Tekst poświęcony jest odpowiedzi na pytanie, jak w sytuacji załamania ekonomicznego reagowali przedstawiciele administracji państwowej, której przedstawicielem był również Jan Krahelski – wojewoda poleski w latach 1926–1932. Pod koniec okresu sprawowania urzędu niejednokrotnie artykułował on swoje poglądy na temat stanu województwa i pożądanych środków, które powinny zneutralizować skutki kryzysu. Tekst oparty jest o materiał archiwalny pozyskany z archiwów Polski, Białorusi i Rosji. Krahelski był zwolennikiem umiarkowanej polityki narodowościowej. Odżegnywał się od polonizacji mniejszości narodowych i niemal do końca sprawowania stanowiska wojewody starał się nie eskalować represji politycznych. Radykalizacja nastrojów społecznych związana z pogłębiającym się załamaniem ekonomicznym zmusiła go do rewizji stanowiska w kwestii metod zapewnienia bezpieczeństwa wewnętrznego. Analiza materiału źródłowego, dla której ważnym punktem odniesienia jest również wystąpienie zbrojne do jakiego doszło w lecie 1932 r. na pograniczu powiatu koszyrskiego (województwo poleskie) i kowelskiego (województwo wołyńskie), wskazuje, że administracja w województwach wschodnich mogła właściwie diagnozować ogólny stan powierzonego jej terytorium, ale jednocześnie niedoskonale rozpoznać jego źródła, w efekcie czego mogła zostać zaskoczona załamaniem porządku. </p>
Foveal serous detachment and its association with body mass index and severity in diabetic retinopathy
Authors: Raj Kirthi , M Sadiqulla 
Published: December 2020

To determine the prevalence of foveal serous retinal detachment in diabetic macular edema among Indians, establish the affiliation between serous retinal detachment (SRD) and severity of diabetic retinopathy, to study its association with the body mass index (BMI) and demographic profile of these patients. Retrospective single-center analysis was done of all patients with diabetic macular edema at the retina clinic between December 2016 to October 2017. The overall prevalence of serous retinal detachment in diabetic retinopathy was 46.5%. The average central macular thickness (CMT) of patients having sub foveal SRD was 584.6 microns. Statistically, significantly higher mean was found in patients with Proliferative diabetic retinopathy (PDR) having SRD (p-value 0.017) over those with Non-Proliferative diabetic retinopathy (NPDR). A higher prevalence of SRD was noted among men (p-value 0.035) and with patients with higher BMI (p-value 0.0028). Higher prevalence of serous retinal detachment (SRD) was seen in proliferative diabetic retinopathy with a higher prevalence among the Indian population with male predilection and among patients with higher BMI.
To study the relation between central corneal thickness, intro ocular pressure and visual field changes in primary open angle glaucoma
Authors: Patil Rohini , Sujatha Rani 
Published: December 2020

To correlate 3 important factors central corneal thickness, intraocular pressure and visual field changes in the POAG suspects which it helps to predict the onset of POAG and in early diagnosis.In this prospective study, a total 100 patients from 40 to 70 years of age diagnosed as PAOG suspects were included in the study. Slit lamp bio microscopy, ultrasound pachymetry was done to measure CCT and IOP was measured with Goldman applanation tonometer the visual field assessment was done with the octopus field analyser.The patient population consisted of 42 females and 58 males with average age of 51.7 years. Significant and moderate positive correlation between the CCT and IOP was observed for the right side (r)=0.39 and left side(r)=0.36 statistically significant (P=0.001). In our study highest percentage of abnormal (glaucomatous) visual field changes was seen in eyes with low CCT (&#60;510µm) (P=0.008). Mean corrected IOP reading was 21.43 mmHg for the 14 patients with abnormal visual fields on right side and this was statistically significant at P=0.01.Thinner corneal readings in south Indian population especially when presenting at younger age should alarm the ophthalmologist to evaluate the patient thoroughly for glaucoma and should be followed up for the progression of glaucoma.
Placebo-controlled, safety and efficacy study of topical atropine (0.01%) in myopic children
Authors: Sanwaliya Brijesh , Nainiwal Sanjeev K , Porwal Rakesh , Sarraf Akshay , Sharma Vijaya 
Published: December 2020

To evaluate the safety and efficacy of (0.01%) topical atropine in controlling the progressive myopia in children.Clinical study entitled as Placebo-controlled, safety and efficacy study of (.01%) topical atropine in children with progressive myopia. In this prospective case control study 80 children with regular follow-up were divided into a subgroup of 40 children who received atropine eyedrops (0.01%) every night, and a subgroup of 40 children, who remained untreated, served as controls.The changes in refraction and axial length of 160 eyes in 80 children were collected and compared for patients treated with 0.01% atropine eyedrop and those with 0.5% carboxymethylcellulose eye drops (control) at 6 months, 12 months and 24 months.The initial spherical equivalent of refractive status range was between –1.5 and –14.25 DS.Mean myopia progression for the group of patients treated with 0.01% atropine eye drop was –0.34 ± 0.43 DS/year, significantly lower than that of the control group of –1.08 ± 0.57 DS/year and axial length 0.12+0.23mm/year (cases)compared to controls 0.48+0.29mm/year with p value &#60;0.05.0.01% atropine is effective in controlling progression of myopia in children age group 5-16 years with no side effects.
A comparative study of aerobic bacterial conjunctival flora in type II diabetes mellitus and non-diabetic individuals who attends to department of ophthalmology at a teaching institute
Authors: Asritha B , Gangapalli Lahari 
Published: December 2020

Normal conjunctival flora have important role in the healthy functioning of eye like maintenance of surface homeostasis and prevention and/or causation of ocular infection. Objective of this study is to investigate the conjunctival aerobic bacterial flora in diabetic patients and nondiabetic subjects with regard to the management of diabetes which is assessed by glycated hemoglobin levels. A prospective study carried out to compare the conjunctiva microflora in 50 diabetes mellitus type II and age matched 50 non-diabetic healthy individuals. Swab was taken from all the participants by rubbing sterile cotton swab to inferior palpebral conjunctiva. Bacterial culture processed using blood agar, chocolate agar, eosin methylene-blue lactose sucrose agar and sabouraud dextrose agar. The bacterial flora identified using microbiology procedure. The rate of bacterial isolate determined as 40% and 34% in diabetes mellitus type II and non-diabetic healthy subjects. In these diabetic group, 30% positive for , 20% for , 10% for , 10% for coagulase-negative Staphylococcus and 30% for more than one bacteria. In non-diabetic group, 52.9% positive for 23.5% for coagulase-negative Staphylococcus (CNS), 5.8% for and 17.6% for more than one bacteria. There was no statistical significant difference observed in isolated bacteria in diabetic and non-diabetic groups. Gram negative bacterial colonization observed high in diabetic individuals (diabetic group, χ2= 0.156, p = 0.815 and in healthy non-diabetic group, χ2= 4.95, p = 0.035). Bacterial isolates were lower in diabetics younger than 40 years of age compared with older than 60 years of age. The conjunctival bacterial flora in diabetics differ from non-diabetic subjects. This should be considered preoperatively and postoperatively, for prophylactic and postoperative treatment should be administered accordingly to the diabetic patients.
Research on the Green Finance Development Model of Commercial Banks Based on FinTech
Authors: Cui Weijiang 
Published: December 2020

<p>Since the 1990s, despite the rapid development of China’s economy, environmental pollution and ecological imbalances have become more and more serious. Fintech financial development technology is a financial-related concept in recent years, which has a huge effect on the research of commercial banks to realize the national green finance operation mechanism and effect evaluation. This article mainly studies how Industrial Bank can better improve the green credit risk management system in the context of Fintech, and also learns from Industrial Bank’s risk management of green credit, provides suggestions for the development of green credit risk management in the banking industry, and promotes modern green, and the development of credit risk management system construction.</p>
The Causes of the Collapse of the Bretton Woods System and Its Influence on International Relationship
Authors: Lu Yuzhou 
Published: December 2020

<p>The Bretton Woods System was formulated by Britain and the United States and other countries before the end of World War II, and it could keep the worldwide hegemony of the United States and was closely related to the economic development and post-war pattern of each country. However, in the 1960s, the weaknesses of this system were showed through the Triffin problem. Besides, there were obvious institutional defects as for this system. All of these led to the collapse of the system under the circumstance of uneven development of capitalism. Although the system has already got out of the stage of history, it still influences the economic recovery of various countries around the world, and it is significant to enhance the international power and change the post-war pattern.</p>
Innovación y edad de las empresas: un estudio en empresas argentinas de software
Authors: Camio María Isabel , Romero María del Carmen , Belén Álvarez María 
Published: December 2020

El sector de software y servicios informáticos (SSI) impacta en el desarrollo económico por su carácter transversal. Este estudio, focalizado en las capacidades, considera la innovación como sistémica y multinivel desde un enfoque evolucionista.Para su desarrollo, se aplica el Modelo de Medición de la Innovación SSI (MINIs) (Camio et al., 2016). Además, se calcula el índice del nivel de innovación (INIs) e indicadores de posición y dispersión para concluir sobre el nivel de innovación, las capacidades, los resultados y los impactos para las diferentes categorías de edad en una muestra de 103 empresas argentinas de SSI. También se observan mayores niveles de innovación, capacidades y resultados en las categorías de menor y mayor edad (de 0 y 5 años y más de 20 años).Estos hallazgos aportan a la discusión académica, donde proliferan los resultados contradictorios, llevando el debate al ámbito específico del sector de SSI con una propuesta metodológica que permite extender el estudio a otros ámbitos territoriales.
Pengaruh Pemberian Pupuk Organik terhadap Pertumbuhan dan Produksi Buah Naga (The Influence of Organic Fertilizer to Growth and Production of Dragon Fruit)
Authors: Muas Irwan , Jumjunidang NFN , Hendri NFN , Hariyanto Bambang , Oktariana Liza 
Published: December 2020

<p>Pemupukan merupakan salah satu aspek penting untuk meningkatkan produktivitas dan kualitas buah naga. Penelitian bertujuan untuk mengetahui pengaruh pemberian pupuk organik terhadap pertumbuhan dan produksi buah naga. Penelitian dilaksanakan di kebun petani Nagari Aripan, Kabupaten Solok, Provinsi Sumatra Barat, dimulai sejak Januari sampai dengan Desember 2014. Penelitian disusun berdasarkan Rancangan Acak Kelompok Faktorial dengan dua faktor perlakuan dan tiga ulangan, setiap unit perlakuan terdiri atas tiga tiang. Faktor pertama adalah takaran pupuk organik dengan tiga level, yaitu 5, 10, dan 15 kg/tiang. Faktor kedua adalah interval waktu pemberian pupuk organik terdiri atas empat level, yaitu 1, 2, 3, dan 4 bulan. Hasil penelitian menunjukkan bahwa pemberian pupuk organik secara nyata dapat meningkatkan pertumbuhan (jumlah cabang), jumlah produksi dan kualitas buah (grade/ukuran buah, TSS). Pemberian pupuk organik juga dapat meningkatkan kandungan hara pada tanah dan tanaman. Aplikasi pupuk organik dengan takaran 15 kg dan interval 1 bulan berpengaruh nyata terhadap pertumbuhan (jumlah cabang), produksi, dan kualitas buah (grade/ukuran buah) tertinggi. Implikasi dari penelitian ini adalah dalam meningkatkan pertumbuhan dan produksi buah naga perlu dilakukan aplikasi pupuk organik.</p><p><strong>Keywords</strong></p><p>Pupuk organik; Pertumbuhan; Produksi; Buah naga</p><p><strong>Abstract</strong></p><p>Fertilization is one of important aspect in improving the productivity and quality of dragon fruit. This study aims to determine the effect of organic fertilizer on the growth and production of dragon fruit. The research was conducted from January to December 2014 at farmer orchard in Solok District, West Sumatra. The study was prepared based on a Factorial RCBD with two factors and three replicates, each treatment consisting of three pillars. First factor was organic fertilizer dose with three levels (5, 10, and 15 kg/pillar). Second factor was the interval application of organic fertilizer consisting of four levels (1, 2, 3, and 4 months). The results showed that the provision of organic fertilizer can significantly increase the growth (number of branches), amount of production and quality of fruit (grade/fruit size,TSS). Provision of organic fertilizers can also increase the nutrient content of soil and plants. Application of organic fertilizer with a dose of 15 kg and 1 month interval gives the highest growth (number of branches), the highest number of fruit production and quality (grade/fruit size) are significantly. Implication of this research is to increase the growth and production of dragon fruit that needs to be done organic fertilizer application.</p>
Evaluating a multidimensional strategy to improve the professional self-care of occupational therapists working with people with life limiting illness.
Authors: Apostol Courtney , Cranwell Kathryn , Hitch Danielle 
Published: December 2020

Abstract
Background: The term ‘’life limiting conditions’ refers to premature death following decline from chronic conditions, which is a common circumstance in which occupational therapists work with people at the end of life. The challenges for clinicians of working with these patients have long been recognised, and may have a significant impact on their professional self-care. This study aimed to evaluate a multidimensional workplace strategy to improve the professional self-care of occupational therapists working with people living with a life limiting condition.Methods: A pre and post mixed methods survey approach were utilised, with baseline data collection prior to the implementation of a multidimensional workplace strategy. The strategy included professional resilience education, targeted supervision prompts, changes to departmental culture and the promotion of self-care services across multiple organisational levels. Follow up data collection was undertaken after the strategy had been in place for two years. Quantitative data were analysed descriptively, while qualitative data were subjected to thematic analysis. Results: 103 occupational therapists responded (n=55 pre, n=48 post) across multiple service settings. Complex emotional responses and lived experiences were identified by participants working with patients with life limiting conditions, which were not influenced by the workplace strategy. Working with these patients was acknowledged to challenge the traditional focus of occupational therapy on rehabilitation and recovery. Participants were confident about their ability to access self-care support, and supervision emerged as a key medium. While the strategy increased the proportion of occupational therapists undertaking targeted training, around half identified ongoing unmet need around professional self-care with this patient group. Demographic factors (e.g. practice setting, years of experience) also had a significant impact on the experience and needs of participants. Conclusions: The multidimensional workplace strategy resulted in some improvements in professional self-care for occupational therapists, particularly around their use of supervision and awareness of available support resources. However, it did not impact upon their lived experience of working with people with life limiting conditions, and there remain significant gaps in our knowledge of support strategies for self-care of occupational therapist working with this patient group.
Evaluation of Chest CT scan as a screening and diagnostic tool in trauma patients with coronavirus disease 2019 (COVID-19): a cross-sectional study in southern Iran
Authors: Fard Hossein Abdolrahimzadeh , Mahmudi-Azer Salahaddin , Sefidbakht Sepideh , Iranpour Pooya , Bolandparvaz Shahram , Abbasi Hamid Reza , Paydar Shahram , Sabetian Golnar , Mahmoudi Mohamad Mahdi , Zare Masoume , Shayan Leila , Salimi Maryam 
Published: December 2020

Abstract
Purpose: The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. A chest computerized tomography (CT) scan has been introduced as the most sensitive diagnostic method. Therefore, this research aimed to examine and evaluate the chest CT scan as a screening measure of COVID-19 in trauma patients.Methods: This cross-sectional study was conducted in Rajaee Hospital in Shiraz from February to May 2020. All patients underwent unenhanced CT with a 16-slice CT scanner. The CT-scans were evaluated in a blinded manner and main CT scan features were described and classified into four groups according to RSNA recommendation. Subsequently, the first two RSNA categories with the highest probability of COVID pneumonia (i.e. typical and indeterminate) were merged into the “positive CT scan group” and those with radiologic features with the least probability of COVID pneumonia into “negative CT scan group”.Results: Chest CT scan had a sensitivity (68%), specificity (56%), positive predictive value (34.8%), negative predictive value (83.7%), and accuracy (59.3%) in detecting COVID-19 among trauma patients. Also, for the diagnosis of COVID-19 by CT scan in asymptomatic individuals a sensitivity of 100% and a specificity of 66.7% and a negative predictive value of 100% was obtained.Conclusion: Findings of the study indicated that the CT scan's sensitivity and specificity is less effective in diagnosing trauma patients with COVID-19 in comparison to non-traumatic people.