bluuebunny/crossref_metadata_2025_split huggingface dataset:
Norma Pernikahan Dalihan Natolu dan Padan pada Masyarakat Batak Toba dalam Film Mursala: Sebuah Kajian Sosiologi Sastra
Authors: Simatupang Bintang Raphael Cornelius 
Published: December 2024

This research aims to reveal the marriage norms of Dalihan natolu and padan in the Toba Batak community in the film Mursala. The theories used in this research are film narrative theory according to Pratista and literary sociology according to Watt, namely literature as a mirror of society. The data collection method used is literature. Research is conducted through written and audio-visual sources such as videos. The material object of this research is the 100-minute film Mursala. The data taken are images and dialogue text in the film Mursala. The main formal object is marriage norms which are reviewed through the sociological theory of literature by Watt, namely literature as a reflection of society. Meanwhile, the presentation of the analysis results is in the form of a narrative description which is also accompanied by several pictures. The results of this research reveal that there are norms of natolu marriage and soul mate in the film Mursala, played by Anggiat Simbolon and Clarissa Saragih. The family relationship with the Anggiat clan, namely Simbolon and Clarissa, Saragih, are cousins based on the tarombo (genealogy) relationship as descendants of King Naiambaton. This makes their love relationship prohibited by the marriage norms of Dalihan Natolu and Padan. In the end, Anggiat Simbolon's love affair with Clarissa Saragih ended to avoid the heavy sanctions that apply to marriage norms in Toba Batak society, such as being expelled from her hometown and expelled from the scope of her clan. Apart from that, the customary sanctions that apply are related to myths and legends in the Toba Batak community and genetics in general. The Mursala film provides a moral message to the Toba Batak people, namely the importance of carrying out customs and norms that have been preserved for generations by the Ompu Sijolojolo Tubu (ancestors) so that they do not commit violations and are not subject to customary sanctions. More than that, this custom is carried out so that the Toba Batak people do not lose their identity as Toba Batak people. Keywords: Film Mursala, Batak Toba, dalihan natolu, padan, sosiologi sastra, naratif film.
Use of labile HbA1c as a screening tool to minimize clinical misinterpration of HbA1c
Authors: De Muynck Emilie , Lapauw Bruno , Delanghe Joris , Lambrecht Stijn 
Published: December 2024

Abstract

Objectives
Hemoglobin A1c (HbA1c) is an established tool in the diagnosis and follow-up of patients with diabetes. However, in some patients the interpretation of HbA1c results faces challenges due to additional biological variation or non-steady-state conditions. This study aimed to demonstrate the value of the L-HbA1c/HbA1c-ratio as a tool to flag HbA1c results, which do not reflect average glycemia “as expected” in routine clinical practice.

Methods
A total of 450 samples of unique patients were selected based on the L-HbA1c/HbA1c-ratio determined on a Tosoh G8 analyzer resulting in a group with a high ratio (≥0.50), a group with a low ratio (≤0.27) and a group with a normal ratio (0.27–0.50). The relationship between HbA1c and glycemic markers (fructosamine and random glucose) was established for all ratio groups. In a smaller cohort of type 1 diabetes patients, continuous glucose monitoring was used as glycemic marker.

Results
The correlation between HbA1c and glycemia (random glucose and fructosamine) differs significantly between the ratio groups. For the same HbA1c level random glucose levels and protein-corrected fructosamine are higher in the high ratio group compared to the normal and low ratio groups, pointing to an underestimation of the glycemic status by HbA1c in patients with high L-HbA1c/HbA1c-ratios. The sensitivity of a high ratio to predict a glycation gap lower than −1.5 NGSP units is 82 % and the specificity is 65 %.

Conclusions
The results of this study reveal the usefulness of the L-HbA1c/HbA1c-ratio as an additional check in the interpretation of HbA1c results in order to detect HbA1c results not reflecting glycemia as expected.
Nitrogen and boron co-doped carbon dots probe for selectively detecting Hg2+ in water samples and the detection mechanism
Authors: Qiu Lixin , Qi Haiyan , Li Wenbo , Li Jun , Sami Rokayya , Aljuraide N. I. , Abo-dief Hala M. , Helal Mahmoud 
Published: December 2024

Abstract
Mercury ions represent hazardous contaminants with significant adverse effects on human health, wildlife, and vegetation. Therefore, it is crucial to create a sensitive and trustworthy technique for identifying mercury ions. In this study, nitrogen and boron co-doped carbon dots (N,B-CDs) were created via a one-step hydrothermal approach, employing citric acid, polyethyleneimine, and boric as precursors. The resulting N,B-CDs exhibited spherical morphology with an average diameter of 2.60 nm and emitted blue fluorescence with peak emissions at 442 nm (λ
em) upon excitation at 360 nm (λ
ex), yielding a fluorescence quantum yield of 27.34%. Remarkably, N,B-CDs, without any surface modifications, functioned as a direct “turn-off” probe, enabling swift, highly selective Hg2+ detection. The N,B-CDs probe could measure Hg2+ in the linear ranges of 0.40–22 μM and 22–208 μM , with a detection limit of 0.12 μM. The detection mechanism was attributed to dynamic quenching interactions between N,B-CDs, and Hg2+. Additionally, the probe was used to detect Hg2+ in both tap and river water, and the recovery rates ranged from 87.20 to 108.20% (RSD <4.89%). These findings highlighted the method’s considerable practical potential for detecting Hg2+ in environmental water.
Heavy metals in road dust from typical old industrial areas of Wuhan: Seasonal distribution and bioaccessibility-based health risk assessment
Authors: Liu Yuanyuan 
Published: December 2024

Abstract
Heavy metals (HMs) in urban road dust could cause human health risk through potential pathways, especially in industrial areas. To identify pollution sources and propose countermeasures, the seasonal distribution of five HMs (Cu, Cr, Zn, Pb, and Cd) were analyzed from 27 sites of Qingshan Industrial District (QSD) and their induced human health risk was assessed using a developed bioaccessibility-based risk assessment model. Results showed that: (1) The concentrations of five HMs were Zn > Cr > Pb > Cu > Cd. Compared with the background values of each element, the dust enrichment capacity in summer was Zn > Pb > Cd > Cu > Cr, and in winter was Cd > Zn > Pb > Cu > Cr. (2) There was no non-carcinogenic risk in road dust in QSD and children’s total non-carcinogenic risk was higher than adults. The non-carcinogenic exposure of each HM was ingested > dermal contact > respiratory inhalation. (3) Cu-Zn-Pb-Cd mainly came from the combined pollution of traffic and industry, and Cr came from the pollution of the steel industry and natural sources. (4) Based on the assessment results, Cr, Zn, Pb, and Cd were determined as the priority control HMs.
Robust H

∞
filter-based functional observer design for descriptor systems: An application to cardiovascular system monitoring
Authors: Tunga Pabitra K. , Jaiswal Juhi , Tomar Nutan K. 
Published: December 2024

Abstract
In this article, we present a novel approach for robust state estimation in linear uncertain descriptor systems, with a specific focus on the cardiovascular system (CVS) as a case study. Descriptor systems, which extend traditional state-space representations by incorporating algebraic constraints, present significant challenges in observer design, especially under conditions of uncertainty. To address these challenges, we propose the design of a functional observer using the

H

∞

{H}_{\infty }

filter approach, capable of managing uncertainties arising from both external disturbances and variations in system parameters. The observer is designed using a unique linear matrix inequality framework, which ensures the stability and performance of the estimation error system. The convergence of the estimation error is rigorously analyzed using the Lyapunov method. The effectiveness of the proposed method is demonstrated through simulations on a CVS model, highlighting its potential to reliably estimate unknown states in the presence of uncertainties.
Foreign Translators Group in the PRC From 1949 to 1966: A STP Perspective
Authors: Chen Longzhan 
Published: December 2024

Abstract
Throughout the history of translation in China, almost every major translation movement has been accompanied by the activities of foreign translators. China, during the seventeen years from 1949 to 1966, absorbed a large number of foreign translators, who made significant contributions to the translation profession of the People’s Republic of China (PRC). These foreign translators participated in China’s translation practice, resulting in distinct characteristics of the translators group. This article takes the concept of the “translator community” of the State Translation Program (STP) as the departing point to explore the characteristics of the foreign translators group engaged in STP in China from 1949 to 1966 and digs out the reasons behind the generation of the foreign translators group. It is found that the foreign translators group in the early 17 years after the founding of the PRC are specifically manifested as the translator positioning of state translators, the predominant translator identity of non-professionals, and the translator image of “gears” and “repairmen.” The generation of these groups is the result of multiple factors, including the state’s strategic requirement for translation output, the state’s macro-regulation of the allocation of translation talent resources, as well as the state’s manipulation of the translation process.
Absence of global solutions to wave equations with structural damping and nonlinear memory
Authors: Kirane Mokhtar , Nabti Abderrazak , Jlali Lotfi 
Published: December 2024

Abstract
We prove the nonexistence of global solutions for the following wave equations with structural damping and nonlinear memory source term

u

t
t

+

(

−
Δ

)

α

2

u
+

(

−
Δ

)

β

2

u

t

=

∫

0

t

(

t
−
s

)

δ
−
1

∣
u

(

s

)

∣

p

d
s

{u}_{tt}+{\left(-\Delta )}^{\tfrac{\alpha }{2}}u+{\left(-\Delta )}^{\tfrac{\beta }{2}}{u}_{t}=\underset{0}{\overset{t}{\int }}{\left(t-s)}^{\delta -1}{| u\left(s)| }^{p}{\rm{d}}s

and

u

t
t

+

(

−
Δ

)

α

2

u
+

(

−
Δ

)

β

2

u

t

=

∫

0

t

(

t
−
s

)

δ
−
1

∣

u

s

(

s

)

∣

p

d
s
,

{u}_{tt}+{\left(-\Delta )}^{\tfrac{\alpha }{2}}u+{\left(-\Delta )}^{\tfrac{\beta }{2}}{u}_{t}=\underset{0}{\overset{t}{\int }}{\left(t-s)}^{\delta -1}{| {u}_{s}\left(s)| }^{p}{\rm{d}}s,

posed in

(

x
,
t

)

∈

R

N

×

[

0
,
∞

)

\left(x,t)\in {{\mathbb{R}}}^{N}\times \left[0,\infty )

, where

u
=
u

(

x
,
t

)

u=u\left(x,t)

is the real-valued unknown function,

p
>
1

p\gt 1

,

α
,
β
∈

(

0
,
2

)

\alpha ,\beta \in \left(0,2)

,

δ
∈

(

0
,
1

)

\delta \in \left(0,1)

, by using the test function method under suitable sign assumptions on the initial data. Furthermore, we give an upper bound estimate of the life span of solutions.
Crosstalk between miRNAs and signaling pathways in the development of drug resistance in breast cancer
Authors: Amiri Reza , Nabi Poorya Najjari , Fazilat Ahmad , Roshani Fatemeh , Nouhi Kararoudi Alireza , Hemmati-Dinarvand Mohsen , Valilo Mohammad 
Published: December 2024

Abstract
One of the biggest challenges of today’s society is cancer, which imposes a significant financial, emotional and spiritual burden on human life. Breast cancer (BC) is one of the most common cancers that affects people in society, especially women, and due to advanced treatment strategies and primary prevention, it is still the second cause of cancer-related deaths in society. Various genetic and environmental factors are involved in the development of BC. MicroRNAs (miRNA)s are non-coding RNAs, that the degradation or inhibition of them plays an important role in the prevention or development of cancer by modulating many cellular pathways including apoptosis, drug resistance, and tumorigenesis. Drug resistance is one of the important defense mechanisms of cancer cells against anticancer drugs and is considered one of the main causes of cancer treatment failure. Different miRNAs, including mir-7, mir-21, mir-31, and mir-124 control different cell activities, including drug resistance, through different pathways, including PI3K/AKT/mTOR, TGF-β, STAT3, and NF-kB. Therefore, cell signaling pathways are one of the important factors that miRNAs control cellular activities. Hence, in this study, we decided to highlight an overview of the relationship between miRNAs and signaling pathways in the development of drug resistance in BC.
An in vitro investigation on the physicochemical properties of different quercetin formulations
Authors: Ibi Afoke , Chang Chuck , Zhang Yiming , Kuo Yun Chai , Du Min , Roh Kyle , Gahler Roland , Solnier Julia 
Published: December 2024

Abstract

Objectives
Quercetin is a naturally occurring plant flavonoid commonly used as a nutritional supplement due to its antioxidant and anti-inflammatory properties. Its well-known low bioavailability has led to the design of different quercetin formulations by various commercial entities seeking to market a highly bioavailable quercetin product. This study investigates four different commercially available quercetin formulations (LMQ, QUX, QUO, and QUV) for their physicochemical properties that influence bioavailability. LMQ and QUX are liquid-based formulations while QUO and QUV are solid powder-based formulations.

Methods
Studies were conducted on particle size using a particle size analyzer; solubility (in water, simulated gastric and intestinal fluid) using Ultra High Performance Liquid Chromatography (UHPLC) to quantify the quercetin content; intestinal permeability and toxicity using Caco-2 cells and HepG2 liver cells.

Results
LMQ and QUX had the narrowest particle size distribution as well as the highest solubility while QUO and QUV had the widest particle size distribution but the poorest solubility. One formulation (QUO) exhibited a significant reduction in cell viability with HepG2 and Caco-2 cells including a significant decrease in TEER value change (−39.0 %; p<0.01); its higher Caco-2 cell permeability (Papp 2.85 × 10−4 ± 4.22 × 10−5; p<0.05) likely resulted from reduced membrane integrity. The other formulations significantly increased the TEER value within the first 4 h (≥22.7 %; p<0.05).

Conclusions
The particle size distribution of each of the individual formulations reflected their solubilities in water and gastrointestinal fluids. Despite QUO having the highest permeability, its negative change in TEER value over time revealed its evident cytotoxic effects. QUV performed poorly in terms of solubility, and permeability. LMQ and QUX were the most consistent across each study with LMQ performing better than QUX overall. Findings of this study present one formulation (LMQ) with superior intestinal absorption while maintaining high cell viability, thus making it one of the safer and more effective quercetin formulations.
The Corrupted “Wheel of Life”: An Essay on Ouroboroses
Authors: Uzlaner Dmitry 
Published: December 2024

Abstract
The focus of this article is a symbolic image often found in world mythology – a giant snake or a dragon biting its own tail. This image is usually denoted by the Greek word “ouroboros” (οὐροβόρος), which means literally “eating its own tail.” This essay is devoted to an interpretation of this symbol, which the author sees as leading to the much broader topic of human unfreedom and the forms that this unfreedom takes. The first section deals with the unique features of Gnosticism which have made it appealing in extremely varied times and situations. Gnosticism will be the basis for my considerations about ouroboros. The author’s reflections start from understanding the Gnostic worldview as an expression of apprehensiveness about the radical otherworldliness of the human spirit and its alienation from the universe. The second section deals with the symbolism of the ouroboros and its place in Gnostic conceptual schemes as a reference to the closed cycle of nature that enslaves the human spirit. The third section attempts to decipher layer by layer the Gnostic conceptions associated with the ouroboros. Various levels of interpretation are identified: literal, mythological–magical, psychological-ascetic, and sociopolitical. In the fourth section, the author connects Gnostic ideas with Christianity by interpreting St. Paul’s Epistles, particularly his ideas concerning rulers and authorities. The place occupied by the ouroboros in the Christian universe is analyzed. The last section relies on the ideas of René Girard, Jacques Lacan, and Alain Badiou to illustrate the manifestations of the ouroboros in different dimensions of human existence, both individual and collective, with special emphasis on human desire and its futile circlings.
ПРОБЛЕМЫ РАСПРЕДЕЛЕНИЯ И СООТНЕСЕНИЯ ЗАТРАТ ПРИ ВНЕДРЕНИИ И ИСПОЛЬЗОВАНИИ ЦИФРОВЫХ ТЕХНОЛОГИЙ В ПРОИЗВОДСТВЕННЫХ СИСТЕМАХ
Authors: Бесфамильная Евгения Викторовна , Сальникова Инна Ивановна , Буракова Лариса Дмитриевна 
Published: December 2024

Целью исследования является определение проблем и возможных путей решения при осуществлении процессов аллокации затрат при создании и функционировании информационных систем на промышленных предприятиях и производственных системах.
Методологическую базу исследования представляют научные публикации, анализ национального и зарубежного опыта компаний в области аллокации затрат, а также математический анализ и элементы регрессионно-корреляционного анализа.
Результаты исследования. Был проведен анализ возможных путей решения проблем аллокативного распределения внутренних ресурсов производственных систем при внедрении и использовании цифровых технологий в практике российских предприятий. Инструментами математического моделирования показано, как возможно получить значения полных затрат по всем подразделениям организации и осуществить перенос совокупных затрат сервисных подразделений на бизнес-подразделения.
Перспективу исследования составляет создание и разработка необходимого инструментария для управления затратами на предприятии и выработка критериев для определения экономической эффективности при принятии стратегических решений
ТЕОРЕТИКО-МЕТОДИЧЕСКИЕ ОСНОВЫ СИСТЕМЫ УПРАВЛЕНИЯ СЕЛЬСКОХОЗЯЙСТВЕННОГО ПРОИЗВОДСТВА ПРЕДПРИЯТИЙ АГРОПРОМЫШЛЕННОГО КОМПЛЕКСА
Authors: Салтанова Ангелина Георгиевна , Пахомова Антонина Александровна 
Published: December 2024

Целью исследования является определение теоретико-методических основ системы управления сельскохозяйственным производством на предприятиях АПК, выявление проблем, постановка задач и векторов систематизации стратегического управления производственным потенциалом предприятий для стабилизации хозяйственного управления региональной системы аграрного производства и построения эффективных целевых планов по развитию сельскохозяйственной отрасли.
Методологическую базу исследования представляют базисные положения концепции устойчивого развития. К используемым научным методам относятся сравнительный, причинно-следственный и статистический анализ.
Результаты исследования. В основе проводимого исследования лежит анализ теоретических и методических тезисов ведения грамотного и эффективного управления производственным процессом на предприятиях АПК, выделение насущных проблем и разработка вариантов их решения с целью стабилизации производственного процесса в отрасли сельского хозяйства. Авторами определены причины и актуальность текущего исследования по поиску действенных практических теоретико-методических рекомендаций организации на предприятиях АПК качественной системы управления, которая является составляющей частицей системы управления АПК региона и страны в целом. Авторами исследован термин «эффективность» для аграрного производства; отражены определения термина, данные разными экономистами; предложена авторская трактовка термина «эффективность» для аграрного производства; выделены виды эффективности и их актуальность для построения качественной системы управления; перечислены элементы системы управления; разработана схема системы управления сельскохозяйственного предприятия с уклоном на основной вид деятельности или специализацию, практическое использование которой обеспечит возможность устойчивого функционирования предприятий АПК в долгосрочной перспективе.
Перспективы исследования заключаются в формировании теоретической и методической базы основ системы управления сельскохозяйственным производством на предприятиях АПК, что в свою очередь будет способствовать грамотному и системному построению в рамках предприятия системы управления, решающей основные задачи: участие в госпрограммах, получение целевого финансирования, развитие социальной инфраструктуры села, внедрение достижений НИОКР и НТП в агропроизводство, применение новейших информационно-консультационных платформ, выход на новые рынки сбыта, эффективность построения производственного процесса от четко сформированного управленческого процесса, максимизация доходов предприятия и сотрудников, насыщение потребности населения в агротоварах.
ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ ЭРГОКУЛЬТУРЫ В СОВРЕМЕННОМ МИРЕ
Authors: Кузьменко Александр Анатольевич 
Published: December 2024

Цель исследования — раскрыть особенности развития эргокультуры в современном обществе.
Методологическую основу работы составляют исследования Брянской научно-философской школы социально-техногенного развития мира. Используются междисциплинарный, системный социотехноприродный и эргоцентрический подходы.
Междисциплинарный подход представляет собой интеграцию различных научных дисциплин, способствующую всестороннему осмыслению сложных процессов, происходящих в современном мире. Системный социотехноприродный подход представляет собой интегративную методологию, используемую для анализа глобальных взаимосвязанных процессов, происходящих в социальной сфере, техносфере и биосфере. Эргоцентрический подход рассматривает особенности взаимодействия человека с предметно-пространственной средой жизнедеятельностью и её технологиями.
Результаты исследования. Демонстрируются основные подходы к осмыслению важности трансформации эргокультуры социально-техногенного мира в эргокультуру социально-биосферной реальности. В данной статье эргокультура рассматривается как новая форма общественной культуры.
Перспективы исследования. В результате исследования будет показан вектор развития эргокультуры, способствующей переходу от социально-техногенного к социально-биосферному развитию.
ПРОЦЕСС МОТИВАЦИИ ПЕРСОНАЛА КАК ФАКТОР ПОВЫШЕНИЯ КОНКУРЕНТОСПОСОБНОСТИ ОРГАНИЗАЦИИ
Authors: Левченко Наталья Александровна 
Published: December 2024

Целью исследования является рассмотрение механизмов повышения эффективности формирования конкурентоспособности организации через процесс эффективной мотивации персонала.
Методологическую базу исследования представляют теоретические аспекты профессиональной мотивации, рассматривающие их как стимул роста эффективности профессионализма с учетом современных требований рынка труда на территории Российской Федерации. Реализация актуальных проблем профессиональной деятельности, стоящих перед органами управления различного уровня, требует особого внимания как в теоретическом, так и практическом аспекте.
Результаты исследования. Одним из приоритетных результатов проведенного исследования является анализ современных требований к уровню компетентности, образования и обучению персонала. Рассмотренные особенности осуществления мониторинга компетентности персонала на всех уровнях управления требуют пристального изучения с учетом текущих социально-экономических тенденций.
Перспективу исследования составляет углубленный анализ проблем мониторинга компетентности персонала организаций, позволяющий отразить специфику кадровых процессов с учетом современной социально-экономической ситуации.