bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic yield of endoscopic ultrasound-guided tissue acquisition for small solid pancreatic lesions
Authors: Mie Takafumi , Sasaki Takashi , Kanata Ryo , Furukawa Takaaki , Takeda Tsuyoshi , Kasuga Akiyoshi , Matsuyama Masato , Ozaka Masato , Sasahira Naoki 
Published: September 2020

Abstract
Background and study aims Endoscopic ultrasound (EUS)-guided tissue acquisition is sometimes required to diagnose small solid pancreatic lesions. The aim of this study was to evaluate the diagnostic yield of EUS-guided tissue acquisition for small solid pancreatic lesions and the differences in diagnostic yield among different needles.
Patients and method We retrospectively analyzed consecutive patients who had undergone EUS-guided tissue acquisition for solid pancreatic lesions less than 2 cm between November 2012 and June 2019. Three types of needles were evaluated in this study: a 22-gauge fine-needle aspiration (FNA) Lancet needle, a 20-gauge fine-needle biopsy (FNB) Menghini needle with a lateral forward bevel, and a 22-gauge FNB Franseen needle. We evaluated the diagnostic yield and safety of the procedure using these needles.
Results We analyzed 160 patients with 163 lesions. The overall sensitivity, specificity, and accuracy were 92.0 %, 100 %, and 92.6 %, respectively. In the histological plus cytological diagnosis, accuracies of the Lancet, Menghini, and Franseen needles were 92.7 %, 97.0 %, and 85.7 %, respectively (P = 0.10). In the histological diagnosis alone, the negative predictive values (NPVs) of the Lancet, Menghini, and Franseen needles were 13.3 %, 53.3 %, and 27.3 %, respectively (P = 0.08). Adverse events occurred in four cases (2.5 %): one postprocedural bleeding, two cases of pancreatitis, and one pancreatic abscess.
Conclusions EUS-guided tissue acquisition for small solid pancreatic lesions has a high diagnostic yield and safety. This study suggested a difference in the diagnostic yield of each needle for small solid pancreatic lesions.
Análise da inclinação tibial posterior como fator de risco para lesão do ligamento cruzado anterior
Authors: de Sousa Filho Pedro Guilme Teixeira , Marques Andre Cavalcante , Pereira Leonardo Soares , Pigozzo Breno Almeida , Albuquerque Rodrigo Sattamini Pires e 
Published: September 2020

Resumo
Objetivo O objetivo do presente estudo foi avaliar a relação entre pacientes com lesão do ligamento cruzado anterior (LCA) por trauma indireto e o aumento da inclinação posterior da tíbia.
Métodos Estudo retrospectivo, realizado por análise de prontuários e radiografias digitais de pacientes, presentes em banco de dados de um hospital terciário de ortopedia e traumatologia. A amostra foi composta por dois grupos, sendo o primeiro formado por pacientes com diagnóstico de lesão do LCA, por trauma indireto, e um grupo controle pareado por idade.
Resultados Cada grupo foi formado por 275 pacientes, cujas medidas de inclinação tibial posterior foram aferidas por 3 especialistas. Observou-se que o grupo dos pacientes com lesão do LCA apresentou slope tibial (em graus) significativamente maior que o grupo controle na amostra total e nas subamostras estratificadas por gênero. Identificou-se como o melhor ponto de corte (cutoff) para o primeiro grupo uma inclinação tibial posterior ≥ 8°, atingindo uma sensibilidade de 63,3% e uma especificidade de 62,5%. O primeiro grupo também apresentou proporção de slope tibial ≥ 8° (63,3%), significativamente maior que o grupo controle (37,5%), com razão de chances de 2,8.
Conclusão Concluiu-se que o aumento da inclinação tibial posterior está associado com um maior risco para lesão do LCA por trauma indireto, principalmente para valores ≥ 8°,
Quadris espásticos da paralisia cerebral – Estudo retrospectivo do salvamento com a cirurgia de McHale
Authors: Yamada Helder Henzo , Amato Neto Dante Galvanese , Malpaga Juliano Mangini Dias , Fucs Patricia Maria de Moraes Barros 
Published: September 2020

Resumo
Objetivo Fazer uma avaliação retrospectiva e transversal quanto à melhora da dor e do posicionamento de todos os pacientes portadores de paralisia cerebral (PC) espástica com deformidade grave no quadril submetidos ao procedimento de McHale em nosso centro. Secundariamente, objetivou-se analisar as possíveis complicações do procedimento.
Métodos Foram analisados todos os pacientes consecutivos tratados no período entre 1995 e 2017. Clinicamente, os pacientes deveriam apresentar dor à mobilização do quadril, dificuldade de posicionamento para se sentar e para os cuidados de higiene, e prontuário médico com dados completos; quanto ao grau de função motora, utilizou-se o Sistema de Classificação da Função Motora Grossa (Gross Motor Function Classification System, GMFCS, em inglês). A avaliação radiográfica no período pré-operatório analisou a porcentagem de migração (PM), o tipo de deformidade de acordo com a Escala de Classificação de Quadril na Paralisia Cerebral de Melbourne (Melbourne Cerebral Palsy Hip Classification Scale, MCPHS), e a deformidade da cabeça femoral. No período pós-operatório, analisaram-se a presença de migração proximal do fragmento do fêmur proximal, as alterações e/ou a falha do implante utilizado, e a possível ossificação heterotópica. Consideraram-se como desfechos: D1- satisfatório: remissão da dor, mobilidade indolor, melhora do posicionamento; e D2- insatisfatório: falha no procedimento, que necessitou de reabordagem cirúrgica.
Resultados No total, 47 pacientes (53 quadris) foram tratados. Funcionalmente, quanto à classificação no GMFCS, 43 pacientes eram GMFCS V (91%), 3 pacientes eram GMFCS IV (6%), e 1 paciente era GMFCS III (2%). A média da idade foi de 13 anos e 2 meses. O tempo de seguimento variou de 1 ano a 15 anos e 4 meses, com média de 4 anos e 8 meses. Quanto ao desfecho da cirurgia de McHale, ele foi satifatório (D1) em 36 pacientes (41 quadris), perfazendo 77% dos nossos casos, e insatisfatório (D2) em 11 (23%) casos.
Conclusão A cirurgia de McHale é uma opção no tratamento para os níveis IV e V, mas devemos estar alertas para as possíveis complicações.
Complications and Solutions in Propeller Flap Surgery
Authors: Cajozzo Marta , Jiga Lucian P. , Jandali Zaher , Muradov Mismil , Pignatti Marco , Cordova Adriana , D'Arpa Salvatore 
Published: September 2020

AbstractPropeller perforator flaps (PPFs) have long been proven as valid reconstructive tools for a wide range of soft tissue defects in different body regions. During the last decade, despite their numerous advantages, many authors have thoroughly analyzed outcomes of these flaps, sometimes discouraging their use mainly because of a high failure rate. Accurate patient selection, adequate preoperative planning, and an appropriate dissection technique seem to potentially improve outcomes. Our study provides a review of the relevant literature related to PPF complications and of our experience, describing reasons for failure, measures for preventing them, and approaches for a prompt evaluation and management of complications.
Precision Medicine, Artificial Intelligence, and Genomic Markers in Urology. Do we need to Tailor our Clinical Practice?
Authors: Chavarriaga Julián , Moreno Camila 
Published: September 2020

AbstractPrecision medicine plays a key role in urological oncology practice nowadays, with the breakthrough of the poly (ADP-ribose) polymerase inhibitors (PARPi), which play a critical role in different DNA damage repair (DDR) pathways, the immune checkpoint inhibitors, the genomic expression profiles and current genome manipulation-directed targeted therapy. Information and technology (IT) are set to change the way we assess and treat patients and should be reviewed and discussed. The aim of the present article is to demonstrate a detailed revision on precision medicine, including novel therapeutic targets, genomic markers, genomic stratification of urological patients, and the top-notch technological breakthroughs that could change our clinical practiceWe performed a review of the literature in four different databases (PubMed, Embase, Lilacs, and Scielo) on any information concerning prostate, bladder, kidney and urothelial cancer novel treatments with PARPi, immune checkpoint inhibitors (ICIs), targeted therapy with fibroblast growth factor receptor inhibitors (FGFRi), and theranostics with prostate-specific membrane antigen (PSMA) targeted monoclonal antibodies. Artificial intelligence, machine learning, and deep learning algorithm in urological practice were also part of the search. We included all articles written in English, published within the past 7 years, that discussed outstanding therapies and genomics in urological cancer and artificial intelligence applied to urology. Meanwhile, we excluded articles with lack of a clear methodology and written in any other language than English.One-hundred and twenty-six articles of interest were found; of these, 65 articles that presented novel treatments of urological neoplasms, discussed precision medicine, genomic expression profiles and biomarkers in urology, and latest deep learning and machine learning algorithms as well as the use of artificial intelligence in urological practice were selected. A critical review of the literature is presented in the present article.Urology is a constantly changing specialty with a wide range of therapeutic breakthroughs, a huge understanding of the genomic expression profiles for each urological cancer and a tendency to use cutting-edge technology to treat our patients. All of these major developments must be analyzed objectively, taking into account costs to the health systems, risks and benefits to the patients, and the legal background that comes with them. A critical analysis of these new technologies and pharmacological breakthroughs should be made before considering changing our clinical practice. Nowadays, research needs to be strengthened to help us improve results in assessing and treating our patients.
Propeller Flaps for the Anterior Trunk
Authors: Ogawa Rei 
Published: September 2020

AbstractVarious types of propeller flaps from multiple donor sites can be used to reconstruct anterior trunk skin defects. The actual selection depends on the condition and location of the recipient site, especially if it is to be the chest or abdomen that requires attention. Before surgery commences, it is always important to use an imaging analyses such as computed tomography angiography to examine and identify perforators that could perfuse a perforator-pedicled propeller flap (PPPF), as it is the most multifaceted imaging technique. Clusters of perforators that can be commonly used for the “workhorse” PPPFs for the thoracic and abdominal regions are the internal mammary artery perforator, the musculophrenic artery perforator, and the deep inferior epigastric perforator. These perforators are reliable and large enough to support long and large propeller flaps that will cover most defects in this region, while still allowing primary donor-site closure.
Smartphone Thermal Imaging Can Enable the Safer Use of Propeller Flaps
Authors: Hallock Geoffrey G. 
Published: September 2020

AbstractThe use of thermography for the identification of cutaneous “hot spots” that coincide with perforators is not a new concept, but the required professional cameras may be prohibitively expensive. Only relatively recently, incredibly cheap but adequate thermal imaging cameras have become available that work in concert with the ubiquitous cell phone. This can now serve as a rapid, accurate, and complementary method for finding a perforator sufficient to serve as the hub for a perforator pedicled propeller flap. In addition, the preferred direction of rotation about that hub, effect of flap insetting on perfusion, and then postoperative monitoring are possible by proper interpretation of corresponding thermograms. Every reconstructive surgeon should be able to obtain this device, and then easily learn what potential attributes for them are available when planning a propeller flap.
Total Hip Arthroplasty in Patients Younger than 35 Is Effective Regardless of Surgical Approach
Authors: Novikov David , Luthringer Tyler A. , Cizmic Zlatan , Rudy Hayeem L. , Mahure Siddharth , Davidovitch Roy I. , Schwarzkopf Ran , Vigdorchik Jonathan M. 
Published: September 2020

AbstractDespite the increasing frequency of younger patients undergoing total hip arthroplasty (THA), very few, if any, studies report on postoperative outcomes that specifically compare the two most commonly used approaches in this age group. The purpose of our study is to assess whether surgical approach affects postoperative outcomes in THA patients younger than 35 years. A retrospective analysis of 115 patients younger than 35 years that underwent primary unilateral THA between January 2013 and April 2018 was conducted. Patients were divided into two cohorts: (1) patients that underwent THA utilizing the anterior approach and (2) patients that underwent THA utilizing the posterior approach. Subanalysis controlling for surgical case complexity and use of robotic assistance was performed. Radiographic analysis included measurement of perioperative leg length discrepancies. Of the total 115 patients, 37 were in the anterior THA cohort, and 78 were in the posterior THA cohort. All baseline patient characteristics were similar among both cohorts. Patients in the anterior THA cohort had shorter mean operative times (95 vs. 121 minutes; p < 0.01) and shorter mean hospital length of stay or LOS (1.9 vs. 2.8 days; p < 0.01). Leg length discrepancies, dislocation, revision, and all-cause postoperative complication rates were similar between both cohorts. When excluding complex cases and use of robotic assistance (anterior n = 36, posterior n = 39), there was no difference in operative time, LOS, or postoperative outcomes. Our study suggests that surgically complex patients were more likely to undergo posterior rather than anterior THA. When controlling for surgical complexity and use of robotic assistance, no difference between approach with respect to operative time, hospital LOS, dislocation, revision, and all-cause postoperative surgical complication rates in THA recipients under 35 years of age was found. The results suggest that the anterior and posterior approaches can be equally effective for the majority of young THA patients.
Propeller Flaps in the Upper Extremity: Arm and Forearm Reconstruction
Authors: Malzone Gerardo , Innocenti Marco 
Published: September 2020

AbstractThe propeller flap is an island of skin that is raised on its pedicle (most commonly a single perforator) and can rotate 180 degrees to cover a soft tissue defect. Thanks to these features, the propeller flap brings reliable tissue from outside of the zone of injury while sparing the main vessels of the upper extremity. This technique limits the donor site to the same limb, captures skin characterized by having the same color and texture, does not necessarily need a microvascular anastomosis, and overall reduces the operating time and surgical cost. Our intent here is to present 27 cases with different soft tissue defects of the upper arm and forearm that have been successfully reconstructed using propeller flaps. The surgical technique, with emphasis on the anatomy of the upper arm, is described. In particular, use of a freestyle approach to customize a perforator-based propeller flap to cover defects from small to medium size is detailed. In our experience, the use of a perforator propeller flap in the upper extremity for resurfacing represents both a very reliable and aesthetically pleasant option.
Introduction to “Propeller Flaps”
Authors: Pignatti Marco , Hallock Geoffrey G. 
Published: September 2020

AbstractThe editors of this issue of Seminars in Plastic Surgery dedicated to propeller flaps met in 2009 at the “1st Tokyo Meeting on Perforator and Propeller Flaps.” On that occasion, as part of the advisory panel of the meeting, they contributed to the definition and classification of these flaps. Since then, several evolutions and new applications of propeller flaps appeared in the literature. In 2019, the editors met again in Bologna, Italy, where they decided to collect the experiences from prominent authors in propeller flap surgery and provide them to the readers in this monographic dedicated publication.
Gastrointestinal Malignancies and Venous Thromboembolic Disease: Clinical Significance and Endovascular Interventions
Authors: Li Xin , Partovi Sasan , Gadani Sameer , Martin Charles , Beck Avi , Vedantham Suresh 
Published: September 2020

AbstractGastrointestinal malignancy encompasses a wide range of disease processes. Its incidence and mortality rate rank among the highest of all cancers. Venous thromboembolic disease is a common complication of gastrointestinal malignancy. Anticoagulation remains the first-line therapy. However, for patients who cannot tolerate or have failed anticoagulation, inferior vena cava (IVC) filter placement may be an option. Furthermore, to improve symptom resolution and reduce the severity of postthrombotic syndrome, catheter-directed thrombolysis (CDT) may be an option. Recent randomized trials including the ATTRACT (Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis) trial have shed new light on the efficacy and safety of CDT and related methods. Overall, the decision to proceed with IVC filter placement or CDT must be individualized.
Transdisciplinarity as a discipline and a way of being: complementarities and creative tensions
Authors: Rigolot Cyrille 
Published: September 2020

AbstractTransdisciplinarity is generally defined by the inclusion of non-academic stakeholders in the process of knowledge production. Transdisciplinarity is a promising notion, but its ability to efficiently address the world’s most pressing issues still requires improvement. Several typologies of transdisciplinarity have been proposed, generally with a theoretical versus practical dichotomy (Mode 1/Mode 2), and effort has focused on possible linkages between different types. However, in the last two decades, transdisciplinarity has significantly matured to the extent that the classical theoretical versus practical distinction appears clearly limited. In this paper, a reframing of the debate is proposed by considering transdisciplinarity as a new discipline and as a way of being. The conception of transdisciplinarity as a discipline can be related to the recent development of the broader discipline of “integration and implementation sciences” (i2S), to which “practical” Mode 2 transdisciplinarity is a major contributor. When transdisciplinarity is considered as a way of being, it is inseparable from personal life and extends far beyond the professional activities of a researcher. To illustrate this conception, the work and life of Edgar Morin can be used as an exemplary reference in conjunction with other streams of thought, such as integral theory. Transdisciplinarity as a discipline and transdisciplinarity as a way of being have complementarities in terms of researchers’ personal dispositions and space for expression in academia. The proposed distinction also raises the question of the status of consciousness in transdisciplinary projects, which may be a fruitful controversial topic for the transdisciplinary research community.
Carbon nitride-based light-driven microswimmers with intrinsic photocharging ability
Authors: Sridhar Varun , Podjaski Filip , Kröger Julia , Jiménez-Solano Alberto , Park Byung-Wook , Lotsch Bettina V. , Sitti Metin 
Published: September 2020

Significance
Light-driven microswimmers offer prospects for autonomous microsystems. Understanding their surface catalytic processes responsible for propulsion is essential in tailoring them for specific applications. So far, photocatalytic microswimmers have been limited by the requirement of continuous illumination. Here, we report light-driven 2D carbon nitride-based Janus microswimmers, which show efficient propulsion in aqueous media not only during but also after illumination for about 30 min after 30 s prior illumination, due to so-called solar battery swimming. Contrary to the mainstream reports, we reveal oxygen reduction rather than hydrogen evolution being responsible for propulsion with alcohol fuels. Balancing reaction conditions, we report the realization of light-induced intrinsic charging of a microswimmer, enabling sustained ballistic propulsion in the dark through discharge of accumulated energy.
Forced adaptations of sporting behaviours during the Covid-19 pandemic and their effects on subjective well-being
Authors: Mutz Michael 
Published: September 2020

ABSTRACT
Few studies have shown that exercise withdrawal and forced inactivity lead to negative mood states and increased symptoms of depression. Involuntary inactivity has become reality for millions during the Covid-19 pandemic, as mitigation and containment policies included the closings of sports facilities and leisure infrastructures. Based on representative survey data from Germany (≥14 years, N = 1001), the paper addresses the changes in sport and exercise activities in the pandemic situation and their association with emotional well-being. Findings show a reduced level of emotional well-being in the German population during the Covid-19 pandemic. In particular, those individuals who stopped or considerably reduced their sport and exercise activities during the pandemic report a significant decline of well-being compared to the time before the pandemic. Individuals, who reduced sport and exercise due to external constraints, reported the largest decline in well-being. In contrast, the small group of individuals who intensified their sporting activities during the pandemic stands out with the most positive well-being levels. Irrespective of sport and exercise adaptations, findings additionally show that females report a steeper decline in well-being during the crisis compared to men.
Astronomical Site Monitoring System at Lijiang Observatory
Authors: Xin Yu-Xin , Bai Jin-Ming , Lun Bao-Li , Fan Yu-Feng , Wang Chuan-Jun , Liu Xiao-Wei , Yu Xiao-Guang , Ye Kai , Song Teng-Fei , Chang Liang , He Shou-Sheng , Mao Ji-Rong , Xu Liang , Xiong Ding-Rong , Zhang Xi-Liang , Wang Jian-Guo , Ding Xu , Feng Hai-Cheng , Liu Xiang-Kun , Huang Yang , Chen Bing-Qiu 
Published: September 2020

Abstract
We installed two sets of Astronomical Site Monitoring Systems (ASMSs) at Lijiang Observatory (GMG), for the running of the 2.4-meter Lijiang optical telescope (LJT) and the 1.6-meter Multi-channel Photometric Survey Telescope (Mephisto). The Mephisto is under construction. The ASMS has been running on robotic mode since 2017. The core instruments: Cloud Sensor, All-Sky Camera and Autonomous-DIMM that are developed by our group, together with the commercial Meteorological Station and Sky Quality Meter, are combined into the astronomical optical site monitoring system. The new Cloud Sensor’s Cloud-Clear Relationship is presented for the first time, which is used to calculate the All-Sky cloud cover. We designed the Autonomous-DIMM located on a tower, with the same height as LJT. The seeing data have been observed for a full year. ASMS’s data for the year 2019 are also analysed in detail, which are valuable to observers.