bluuebunny/crossref_metadata_2025_split huggingface dataset:
ROLE OF PLATELET RICH PLASMA IN TREATMENT OF CHRONIC NON-HEALING VENOUS ULCER
Authors: Dekhaiya Firdaus A. , Joshi Jignesh K. , Bamania Sarav 
Published: March 2020

Introduction: Venous ulcers are wounds that are thought to occur due to improper functioning of venous valves, usually of the lower limbs. Considering that PRP is a source of growth factors, and consequently has mitogenic, angiogenic, and chemotactic properties, it represents an adjunctive treatment for recalcitrant wounds. Moreover, PRP provides the wound with adhesive proteins, such as fibrinogen, which are important in wound healing. PRP contain more amount of platelets, cytokines and growth factors which are dispersed in a very small amount of plasma which can be prepared from a sample of centrifuged autologous blood. Application of PRP has been reported to be effective in both acute as well as chronic non healing venous ulcers.
Aim and Objective: To evaluate the efficacy of autologous platelet rich plasma in the management of chronic venous ulcer. Material and Method: A Prospective study conducted on 100 patients of chronic venous ulcers admitted in Sir T. Hospital Bhavnagar from June 2018 to June 2019 after fulfilled our inclusion and exclusion criteria. PRP then injected intalesionally inside and around the periphery of the wound/ulcer. This process was done once/week for 12 weeks. At every week, the area and volume of ulcer was calculated and photographs were taken.
Result: All the patients showed healing of the ulcer with reduction in size of ulcer more than 90% was observed in 72 patients, followed by 80–90% reduction in wound size in 18 patients after the 12 weeks follow-up. Overall, significant reduction in size of ulcer was observed in all the treated patients.
Conclusion: Autologous platelet rich plasma (PRP) as an autologous method, it is biocompatible, simple, safe, affordable and less expensive procedure in the treatment of chronic venous ulcers. PRP is found to be useful in improving and enhancing the healing process in chronic venous leg ulcers without any side effect.
Keywords: Venous ulcer, Platelet rich plasma
MICROBIOLOGICAL ASPECT OF FUNGAL RHINOSINUSITIS: STUDY CONDUCTED IN TERTIARY CARE HOSPITAL OF NORTH INDIA.
Authors: Kaur Shubhdeep 
Published: March 2020

Introduction: Fungal rhinosinusitis is the emerging disease of current era, so isolation of fungus is important aspect to plan the treatment modalities accordingly.
Methods: 50 samples of suspected patients of fungal rhinosinusitis were studied. Various samples like nasal secretion, nasal lavage and tissue were examined on direct microscopy using KOH and processed by standard protocols for fungal culture.
Result: Out of 50 suspected cases fungal rhinosinusitis was seen in 23 (46%) cases. The 40% of cases were positive by direct microscopy using 20%KOH and 46% were positive by fungal culture. The most common fungal isolates was Aspergillus flavus (65.5%) followed by Aspergillus niger (13%).
Conclusion: Aspergillus spp. was the most common isolated species among all the cases of fungal rhinosinusitis.
Keywords: Aspergillus spp., Fungal, Rhinosinusitis.
DO WE NEED ETHICS? – II MBBS STUDENTS PERCEPTIONS IN LEARNING MEDICAL ETHICS.
Authors: A Anupriya , S Priya Banthavi , E Kamala , P Thirumalaikolundusubramanian , N Prabhusaran 
Published: March 2020

Back ground: An Indian Medical Graduate is expected to have knowledge & acquire competencies during his formal medical course, but an understanding of professional values and ethical conduct is essential for fostering the development of a good doctor.The two major aspects of teaching medical ethics include explicit teaching of cognitive base and stage appropriate opportunities for experiential learning and reflection throughout the curriculum.
Material and Methods: It is a classroom based intervention study involving 150 second MBBS students. Self administered, semi-structured questionnaire was devised for this study. The questionnaire consisted of two parts- students perception towards learning medical ethics and their perception on statements of ethical issues which was graded on a 5 point Likert scale. An interactive lecture was done followed by which students were divided into 6 groups and case based discussions were done. Finally reflective narration was done.Statistical analysis was done by EPI Info Software. Results were expressed in mean, standard deviation and paired ‘t’ test was done.
Results: The mean pre-test & post-test score of the students towards learning medical ethics in current curriculum were 2.86 and 3.98 respectively. The mean pre-test and post-test score of students regarding statements on ethical issues were 2.82 & 3.92 respectively.
Conclusion: Medical ethics is one of the neglected topics in healthcare. To strengthen ethical reasoning and judgment in decision making, we need to expose students to various ethical scenarios based on which debates, seminars, interactive workshops can be conducted utilizing the work experience of multidisciplinary medical expertise.
Keywords: Medical ethics, Medical practice, Students
PREVALENCE OF HYPOTHYROIDISM, DELAYED PUBERTY AND DIABETES MELLITUS IN PATIENTS OF Β-THALASSEMIA MAJOR
Authors: Manne Naresh , Gupta Bharat Kumar , Yadav Sandeep Kumar , Singhal Saurabh , Dubey Archana 
Published: March 2020

Background: Beta-Thalassemia is a genetic disorder which is associated with a lot of complications. Frequent blood transfusions result in increased iron deposition in various tissues leading to dysfunction of many vital organs. Endocrine disorders constitute a major part of such complications increasing the morbidity of thalassemia manifold in the affected patients.
Methods: This is a descriptive cross sectional study carried out in 100 diagnosed patients of beta- thalassemia major who had visited the OPD/IPD of Subharti Medical College & affiliated Hospitals, Meerut for routine blood transfusion or for any other complication. Patients were clinically examined and investigated for presence of one or more endocrine disorders on their routine appointments.
Results: Endocrine disorders were detected in a total of 82 patients. Diabetes mellitus was detected in 12% patients, hypothyroidism in 36% patients and delayed puberty was found in 72% patients. Mean serum ferritin level was found to be 5831.0±2860.5 ng/ml in beta-thalassemia Major patients, while it was in normal range in control subjects.
Conclusion: Research concluded with finding of Delayed puberty (72%), Hypothyroidism (36%) and diabetes mellitus as (12%) in beta thalassemia patients who were on regular blood transfusion therapy. Iron overload as serum ferritin level was found to be highly raised in all study case. On the basis of our study we recommend that early detection and management protocols for these endocrinopathies may improve the life prospects of beta-thalassemia Major patients.
Keywords: Endocrine disorders, Hypothyroidism, Delayed puberty, Diabetes Mellitus Serum ferritin, Thalassemia Major.
COMPARISON OF QUANTITATIVE TUBE AGGLUTINATION AND SEMIQUANTITATIVE SLIDE AGGLUTINATION TEST FOR DIAGNOSING OF THE SUSPECTED CASES OF ENTERIC FEVER
Authors: Kaur Shubhdeep , Yadav Harsh , Singh Umed , Narain Mona , Bhardwaj Mayank , Kumar Pushpendra 
Published: March 2020

Introduction: Enteric fever is the major health problem of developing country like India, with a notable morbidity and mortality. Isolation of Salmonella the causative agent from Blood is the standard laboratory method for diagnosis, but it is not available at PHC level. So, rapid and affordable diagnostic test like Widal tube and slide agglutination test are used. The present study was done to comparatively evaluate the Widal slide agglutination and tube agglutination test in detecting enteric fever.
Methods: A total of 500 patients with clinical presentation suggestive of enteric fever were included in the study whose venous blood was collected. All the samples were tested for the presence of anti O and anti H agglutinins against S. typhi and S. paratyphi A by semi quantitative slide and quantitative tube agglutination tests as per standard protocols. The titers of 1:80 (O agglutinins) and 1:160 (H agglutinins) were taken as the significant titer for the diagnosis of enteric fever.
Results: Out of 500 collected samples, 183 (36.6%) was positive by slide agglutination test, whereas, only 145 (29%) were positive by tube agglutination method. The slide test had a sensitivity of 97.2%, specificity of 88.1%, positive predictive value of 77% and negative predictive value of 98.7% as compared to Widal tube agglutination test.
Conclusions: Due to high false positivity shown by slide test, it is suggested that serological diagnosis should not be made solely on the basis of slide test rather its results should be confirmed by using Widal tube agglutination test.
Keywords: Enteric fever, Slide agglutination test, Widal tube agglutination test, Sensitivity, Specificity
TO ASSESS THE OUTCOME OF PATIENTS FOR DAY CARE SURGERY
Authors: Prashar Vishal , Singh Shamsher 
Published: March 2020

Background: Day care surgery offers advantages for health care delivery system around the world and so rates have steadily increased in both developed and developing countries.
Methods: Day care surgery offers advantages for health care delivery system around the world and so rates have steadily increased in both developed and developing countries.
Results: Out of 155 patients 89 (57.4%) had an operative time of 00-30 minutes, 64 (41.3%) had an operative time of 30- 60 minutes, 2 (1.3%) had an operative time of 60-90 minutes and none took more than 90 minutes. Two Patients having an operative time period of 60-90 minutes included laparoscopic procedures converted to open cholecystectomies.
Conclusion: This study clearly shows that day care surgery is feasible and safe.
Keywords: Outcome, day care surgery, Post-operative
COMPARATIVE STUDY OF ANTI-INFLAMMATORY EFFECT OF DICLOFENAC AND ETORICOXIB ON PATIENTS WITH INFLAMED KNEE JOINT
Authors: Jha Amit Kumar , Prasad Raj Ranjan 
Published: March 2020

Non steroidal anti-inflammatory drugs are non-narcotic or non opioid analgesics.Various exogenous and endogenous stimuli incite a complex reaction in vascularized connective tissue called inflammation. Preferential COX-2 inhibitors named diclofenac and Selective COX-2 inhibitor named etoricoxib was taken for my present work and anti inflammatory effect was compared with control and with each other. Student-t-test-was done to compare result. It was found that inflammation varied significantly across the three groups (P=.000) Compared to control, inflammation was less in both diclofenac and etoricoxib (P=.00). Reduction of inflammation with diclofenac was less, in comparison to etoricoxib at end. Etoricoxib is more efficacious than diclofenac.
Keywords: Etoricoxib, Diclofenac, Anti inflammatory effect.
TO STUDY THE INCIDENCE OF PRIMARY CAESAREAN SECTION IN PRIMIGRAVIDA AND MULTIGRAVIDA
Authors: Gothwal Sarika , Meena R K , Meena Rattiram 
Published: March 2020

Background: Caesarean section is one of the commonly performed surgical procedures in obstetrics and is certainly one of the oldest operations in surgery. Methods-This is hospital based prospective study of comparing the primary caesarean section in primigravida and multigravida.
Results: Out of 100 primigravida patients delivered, of it(66.00%) delivered normally and 34 (34.0%) delivered by primary LSCS. Out of 100 multigravida patients delivered and out of which 75 (75.00%) delivered noramally and 22 (22.00%) were primary LSCS.
Conclusion: The rate of primary caesarean section in primigravida is higher than multigravida.
Keywords: Primigravida , Multigravida, Caesarean section.
TO STUDY AND EVALUATE THE EFFICACY OF ORAL THEOPHYLLINE IN ADDITION TO OTHER CONSERVATIVE MEASURES FOR THE TREATMENT OF PDPH.
Authors: Agrawal Sangeeta Bansal , Gupta Richa , Sharma Prerna 
Published: March 2020

To provide analgesia in patients developing PDPH and to study the quality and efficacy of oral Theophylline as an addition to other conservative treatment used for PDPH.
Keywords: Efficacy, Oral, Theophylline, PDPH.
ROLE OF NANOTECHNOLOGY IN DENTAL SCIENCES: A REVIEW
Authors: N Ramakoteswara Rao , E Kranthi kiran Reddy , Gahane Leena , Ranganayakulu SV 
Published: March 2020

Nano technology is the multi disciplinary science and technology, which has emerged as new science exploiting specific phenomena and direct manipulation of materials on nanoscale. Nanotechnology deals with the physical, chemical, and biological properties of structures and their parts at nanoscale dimensions. It's established on the concept by creating functional structures by controlling corpuscles and molecules on a one-by-one basis by different physical and chemical synthesis methods. Developments in materials science and, nano biotechnology is especially forestalled to provide elevates in dental sciences and initiations in oral health-related diagnostic and therapeutical methods.
Keywords: Nano Science, dentistry, Nanocomposite, Nanorobots, Nanomaterials.
DECLARATION OF EPIDEMIC PUBLIC HEALTH WITH NOVEL CORONAVIRUS
Authors: Abdulkareem Rafid A. 
Published: March 2020

Coronaviruses (CoV) are broad enveloped RNA viruses in humans and animals are mostly correlated with enteric and respiratory problems. Within the last decades, incidents of high death rate triggered by the spread of CoV from animals to humans have occurred. Certain pathogen city of CoV is known species-dependent as with the extent of infection; Complications typically appear in closely associated human hosts. Epidemiologists assume that the SARS virus arose in bats (natural reservoirs hosts) that were transferred to persons in Wuhan, China. Presently, the available diagnostic tests are aimed at the traditional early detection of the causes of pneumonia, promote disease prevention efforts and collaborate with research laboratories that can conduct pan coronavirus detection or controlled sequencing. No vaccine is sufficient to protect toward coronaviruses. Also there is no clear treatment for corona virus disease. Patients take comprehensive medication in clinics and typically heal on their own after several times. A vaccine can take up to 45 months to develop. Let’s stay safe during this period of time.
Keywords: Coronaviruses, Spreading, bats, diagnostic, vaccine
EVALUATION OF QUALITY OF LIFE AND PSYCHOLOGICAL IMPLICATIONS IN PATIENTS WITH ROSACEA USING DERMATOLOGY LIFE QUALITY INDEX (DLQI) AND THE HOSPITAL ANXIETY AND DEPRESSION SCALE (HADS)
Authors: Mohta Alpana , Nyati Asha , Agrawal Aditi , Jain Suresh Kumar , Kushwaha Ramesh Kumar , Gautam Umesh , Sharma Pritee 
Published: March 2020

Introduction: Rosacea is a chronic skin disease associated with high levels of psychological distress and a significant impact on quality of life.
Objective: To evaluate the quality of life, depression and anxiety in patients with rosacea.
Material and Methods- Seventy-three patients, aged 18 years or above, with a clinical diagnosis of rosacea were included in the study. All patients completed a Dermatology Life Quality Index (DLQI) questionnaire and a Hospital Anxiety and Depression Scale (HADS) quessionaire.
Results: The mean DLQI score of patients was 7.98 ± 5.86 which signified a moderate impact on quality of life. The mean HADS-A (anxiety) score was 4.83 ± 4.42, while the mean HADS-D (depression) score was 5.22 ± 4.04. Thirteen (17.81%) patients had anxiety HADS-A (≥11 points) while 11 (15.07%) patients had depression HADS-D (≥11 points). Total DLQI score of patients with rosacea correlated positively with anxiety (r = 0.67, p value- <0.001) and depression (r = 0.49, p value- <0.001)
Conclusion: Rosacea is a distressing disease which has a moderate impact on patient’s QOL. Dermatologists must always be vigilant of the psychosocial aspects of rosacea and should opt for the self-perception of rosacea by patients while prescribing a treatment regimen.
Keywords: Rosacea, dermatology life quality index, DLQI, Hospital Anxiety and Depression Scale, HADS
EFEKTIFITAS PENYUSUNAN PROGRAM BIDANG BIMBINGAN KARIER DI SMA SE-PROVINSI BENGKULU
Authors: Aprizal Tri , Hardianti Susi 
Published: March 2020

This study aims to find out: (1) a description of how the teacher guidance and counseling analyze the needs of learners to develop programs field of career counseling in high school Se Bengkulu province, (2) a description of how the teacher guidance and counseling plan organizer program fields career guidance in high school Se Bengkulu province, (3) a description of how the teacher guidance and counseling melakasanakan program field of career counseling in high school Se Bengkulu province, (4) a description of how the teacher guidance and counseling evaluate the results of exercising their program areas of career counseling in high school Se Province Bengkulu, (5) a description of how the teacher guidance and counseling melaporakan results of program implementation in the field of career counseling SMA Se Bengkulu province, (6) a description of how the follow-up guidance and counseling teachers to the field of career guidance program in SMA Se Bengkulu Province. In this study, the analysis is the Program Development Effectiveness in the field of career guidance High School Se Bengkulu Province.
The method in this study using a quantitative approach. The population in this study were 116 high school Se Bengkulu province. The sample in this study as many as 61 people. Data collection techniques in this study using a questionnaire. Data analysis techniques in the study of statistical techniques.
Once the data is collected and analyzed obtained the following results:

The level of needs analysis is carried to the preparation program of career counseling in high school field Se Bengkulu province, in keseluruahan have been effective, but there are some high school in effective gori said.
The level of planning that is carried to the preparation program of career counseling in high school field Se Bengkulu province, in keseluruahan in the category effectively.
The level of implementation of career counseling in high school field Se Bengkulu province, in keseluruahan be at an effective level, but there are some high school has enough effective, ineffective.
The level of program evaluation in the field of career counseling SMA Se Bengkulu province, in keseluruahan are at a level very effective, but there are some high school has a quite effective, and ineffective.
The level of reporting program of career counseling in high school field Se Bengkulu province, in keseluruahan are at a level very effective, but there are some high school has effective enough.
The level of follow-up program of career counseling in high school field Se Bengkulu province, in keseluruahan are at a level very effective, but there are some high school has effective enough.
GAMBARAN TIPE KEPRIBADIAN SISWA DI SMP NEGERI 01 KABUPATEN BENGKULU UTARA
Authors: Zumkasri Zumkasri , Hardianti Susi 
Published: March 2020

This study aims to find out how the personality type description of students in State Middle School 01 North Bengkulu Regency. In this study, the analysis was focused more on sanguistic, melancholy, choleric, and pleasing personality. This type of research is quantitative descriptive research, namely research based on the philosophy of positivism, used to examine certain populations or samples, collecting data using instruments, analyzing data is quantitative. The sample of this study was 10% of the total number of students in SMP Negeri 01 Bengkulu Utara so the number of samples was 60 students. Data collection techniques in this study used a questionnaire. Data analysis techniques in this study The analysis used in this research is descriptive percentage to process data and describe data using the percentage formula.
The findings of this study are that the description of personality types of students varies, this is evidenced by the results of the percentage calculation with Sanguinis personality type by 77%, Melancholic personality type by 2%, Cholesterol personality type by 3%, and Plegmatic personality type by 18%.
Pemilihan Umum (Pemilu) Langsung di Indonesia Perspektif Sosiologis dan Hukum Islam
Authors: Efyanti Yasni , Zufriani Zufriani , Halim Halim 
Published: March 2020

Pemilihan Umum Presiden dan Wakil Presiden merupakan suatu “ritual politik”yang secara periodik dilaksanakan di Indonesia. Berdasarkan sejarahnya, Pemilihan Umum telah dilaksanakan sebanyak 12 (dua belas kali) mulai pemilu pertama tahun 1955 hingga yang terakhir pemilu ke-12 pada tahun 2019. Pemilihan Umum di Indonesia yang menganut sistem pemilihan umum langsung sesuai yang diamanatkan UUD 1945 perubahan ketiga Pasal 22E dan sesuai dengan pasal 2 ayat (1) UUD 1945. Meskipun demikian tetap saja rakyat yang memegang kedaulatan penuh itu bervariasi jenisnya. Ada yang sadar akan demokrasi, ada yang tidak sadar demokrasi, bahkan ada yang tidak tahu akan demokrasi sama sekali. Sebagian masyarakat pun masih ada yang kurang sreg menerapkan sistem pemilu langsung tersebut. Keberatan itu disebabkan belum maju secara ekonomi, dengan tingkat pendidikan relatif rendah, apalagi sistem politiknya belum tegak di atas landasan komitmen berdemokrasi yang kuat. Bila dilihat dalam Islam, Nabi s.a.w. tidak menerima kekuasaan dari siapapun (baca: tidak mewarisi kekuasaan), kemudian Nabi s.a.w. juga tidak meninggalkan petunjuk khusus atau wasiat tentang siapa yang akan menggantikannya dalam posisi kepala Negara, sehingga ketika Nabi s.a.w. wafat yang menjadi permasalahan umat Islam adalah masalah Imamah atau kekhalifahan. Penelitian ini merupakan merupakan penelitian perpustakaan (libraryreaseach), artinya menggunakan pustaka sebagai sumber primer maupun sekunder. Sebagai sumber primer adalah kajian Islam tentang fenomena modern dandata sekunder adalah karya-karya yang berkenaan dengan fenomena perpolitikan di Indonesia. Begitu pula dalam melakukan pengumpulan data, akan dilakukan dengan menelusuri literatur-literatur dan data-data tentang pelaksanaan pemilu di Indonesia dalam 4 kali periode pemilu secara langsung. Untuk mempermudah penelitian ini akan digunakan pendekatan Historis, Deskriptif dan Komparatif. Hasil dari penelitian ini diharapkan mampu memberikan pemahaman yang kuat tentang demokrasi kepada masyarakat sehingga dapat menguatkan komitmen masyarakat dalam berdemokrasi.
VARIASI BAKTERI PADA PENDERITA INFEKSI SALURAN KEMIH (ISK)
Authors: Yashir Muhammad , Apriani Apriani 
Published: March 2020

Infeksi Saluran Kemih (ISK) merupakan penyakit infeksi kedua tersering setelah infeksi saluran pernafasan dan sebanyak 8,3 juta kasus dilaporkan per tahun. Di Indonesia prevalensi ISK berkisar antara 5-15 % dan jumlah penderita ISK mencapai 90-100 kasus per 100.000 penduduk per tahun. baku emas pembuktian ISK dengan melakukan pemeriksaan mikrobiologi yaitu kultur urin dan pemeriksaan urinalisis rutin metode carik celup. Penelitian ini bertujuan untuk mengetahui gambaran hasil laboratorium kultur urin terhadap leukosit esterase dan Eritrosit , dan untuk melihat adanya variasi bakteri pada penderita isk di RS Atmajaya Jakarta Utara.Metode Penelitian studi analisa deskriptif dari 33 sampel atau responden semua umur tanpa batasan di Laboratorium Mikrobiologi RS Atmajaya November – Desember 2017. Hasil penelitian jumlah responden perempuan (52%) lebih banyak dibanding laki-laki (48%). Angka kejadian ISK meningkat pada pasien kelompok umur diatas 40 tahun yaitu 41-60 tahun (10 kasus) , dan >60 tahun (10 kasus). Dari penelitian ini, Escherichia coli (31 %) merupakan mikroorganisme tersering yang menyebabkan ISK.