bluuebunny/crossref_metadata_2025_split huggingface dataset:
A New Dressing System Which Is Waterproof, Breathable, Bacteriostatic, Low-Cost and Reduces the Number of Dressing Changes in the Primary Total Hip Arthroplasty: A Feasibility Study
Authors: Su Shilong , Zhong Da , Wang Chenggong , Gao Fawei , Lei Pengfei , Hu Yihe 
Published: December 2020

Abstract
Background Total hip arthroplasty is one of the most successful operations for the treatment of advanced hip osteoarthritis and osteonecrosis of the femoral head. Periprosthetic joint infection (PJI) is the most serious complication of joint replacement, and postoperative wound complication is the risk factor of PJI, so it is very important to manage the surgical wound. We innovatively invented a new dressing system to reduce the occurrence of postoperative wound complications and improve the quality of life and functional recovery of patients after operation. We designed this clinical study to confirm the clinical safety and feasibility of this new dressing system. Methods A total of 120 patients who underwent the primary unilateral total hip arthroplasty were enrolled in the study. The data collected included the number of dressing changes and postoperative hospital stay, The Visual Analogue Scale (VAS) score, The Harris Hip Score (HHS), The Hip disability and Osteoarthritis Outcome Score (HOOS) and The Short Form-36 (SF-36), ASEPSIS score, The Stony Brook Scar Evaluation Scale (SBSES), wound complications, and satisfaction. We made a statistical analysis of the data. Trial registration: Chinese Clinical Trial Registry, ChiCTR2000033822. Registered 13 June 2020 - Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj=54735 Results The average number of dressing changes was 0.74 ±0.46, and the average postoperative hospital stay was 3.67 ±0.97 days. The new dressing system calculates that the cost of a change of dressing is 33 dollars. The results of VAS, HHS, HOOS, and SF-36 showed that with the implementation of joint replacement and the extension of recovery time, the pain, functional activity, and quality of life of patients were continuously improved. The results of the four indexes of the ASEPSIS score were all 0. The SBSES score was 3.55±0.61 at seven days after operation and 4.38±0.71 at one month after operation. No wound complications were recorded until one month after the operation. One month after the operation, the satisfaction rate was 92.53 ±3.62%. Conclusion We have invented such a new dressing system for surgical wounds after total hip arthroplasty and confirmed the clinical safety and feasibility of the new dressing system.
Integrated Analysis of a circRNA-miRNA-mRNA Axis in Intervertebral Disc Degeneration
Authors: Wei Laifu , Tu Bizhi , Gao Fei , Qian Jun 
Published: December 2020

Abstract
Background: Low back pain (LBP) is a common symptom in daily life and one of the primary causes is intervertebral disc degeneration (IDD). Growing studies have indicated that circular RNAs (circRNAs) are intimately associated with IDD; however, the underlying mechanism has not yet been elucidated. We aimed to explore how circRNAs regulate IDD in an effort to provide novel insight for clinical diagnosis and treatment. Methods: The sequencing data of circRNAs, microRNAs (miRNAs), and mRNA were acquired from Gene Expression Omnibus (GEO) datasets. By analyzing the dataset consisting of a control group and degenerated group, differentially expressed circRNAs, miRNAs, and mRNAs were collected, and then the intersection of circRNAs, miRNAs, and mRNAs was screened. According to these intersectional RNAs, we constructed an integrally circRNA-miRNA-mRNA network. Finally, using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses, we further clarified functions of the intersectional mRNA in IDD. Results: we obtained 620 differentially expressed circRNAs(DEcircRNAs), 13 miRNA (DEmiRNA), 273 mRNAs(DEmRNAs), 12 intersectional miRNAs, and 47 intersectional mRNAs. Finally, based on interactional 8 circRNA, 5 miRNAs and 15 mRNAs, an integrally circRNA-miRNA-mRNA network was constructed. Eight circRNAs, contained hsa_circ_0032254, hsa_circ_0003183, hsa_circ_0032253, hsa_circ_0001293, hsa_circ_0004565, hsa_circ_0091570, hsa_circ_0077526, and hsa_circ_0057552, may regulate IDD onset and progression by acting as competing endogenous RNAs. The results of GO and KEGG analyses implied that the targeted genes might significantly correlate to IDD.Conclusion: our findings improved a better understanding of the circRNA-related ceRNA regulatory mechanism in IDD and offered possible targets for IDD treatment.
The Clinical Outcomes of Ultrasound-Guided Hip Joint Injection in The Treatment of Persistent Pain After Hip Arthroscopy
Authors: Gao Guanying , Fu Qiang , Wu Ruiqi , Liu Rongge , Cui Ligang , Xu Yan 
Published: December 2020

Abstract
Background: To evaluate the short-term and long-term clinical outcomes of ultrasound-guided hip joint injection in the treatment of persistent pain after hip arthroscopy.Methods: Patients who had persistent pain after hip arthroscopy and underwent ultrasound-guided hip injection for treatment between January 2016 and February 2019 were involved. Pre-injection patient-reported outcomes (PROs) and post-injection PROs 1 month after injection and at final follow-up were obtained, including visual analog scale (VAS), modified Harris Hip Score (mHHS), Hip Outcome Score – Sport Specific Subscale (HOS - SSS) and Hip Outcome Score - Activity of Daily Living (HOS – ADL). VAS 10 minutes after injection was also recorded. Patient satisfaction with outcome of injection (graded as excellent, good, fair or poor) was documented at the end of follow-up. Results: A total of 33 patients were involved in this study. The mean follow-up time after injection was 24.1 months. The mean time between surgery and injection was 10.7 months. The VAS, mHHS, HOS-SSS and HOS-ADL improved from 5.6 ± 1.4, 56.4 ± 10.7, 59.1 ± 8.5 and 44.2 ± 17.1 to 3.3 ± 2.1, 67.3 ± 12.7, 69.1 ± 14.7 and 57.2 ± 23.0, respectively at 1 month after injection and improved to 2.4 ± 2.2, 76.4 ± 11.7, 80.3 ± 14.3 and 69.6 ± 23.0 at final follow-up. All results demonstrated statistically significant difference between different time point (P < 0.05). Three (9.1%) patients thought the outcome of ultrasound-guided hip injection was excellent, 8 (24.2%) thought the outcome was good, 9 (27.3%) thought the outcome was fair, and 13 (39.4%) thought the effect of injection was poor.Conclusion: Ultrasound-guided hip joint injection would be a feasible treatment method of persistent pain after hip arthroscopy, especially in older patients, patients with higher BMI and patents who are sensitive to intra-articular injection.Level of Evidence IV.
Comparison of Clinical Outcomes&nbsp;Between Stand-Alone Oblique Lumber&nbsp;Interbody Fusion&nbsp;and Posterior Lumbar Interbody Fusion for Treatment&nbsp;of Degenerative Lumbar Diseases
Authors: Guo Run Peng , Gao Xian Da , Du Pei Yu , Ding Wen Yuan , Ma Lei 
Published: December 2020

Abstract
Background: This study evaluated the clinical and imaging results of oblique lumber interbody fusion (OLIF) and posterior lumbar interbody fusion (PLIF) in the treatment of degenerative lumbar diseases.Methods: The clinical data of 99 patients with degenerative lumbar diseases in the Third Hospital of Hebei Medical University from January 2016 to January 2018 were analyzed retrospectively. 49 cases were dealt with by OLIF (stand-alone) (OLIF group) and 50 cases with PLIF (PLIF group). Clinical and imaging data were collected before surgery and at each follow-up visit. Clinical data included operation time, blood loss, incision length, length of hospital stay, visual analogue score (VAS), Oswestry dysfunction index (ODI), Japanese orthopaedic association (JOA) scores and complications. imaging measurment included the height of segmental intervertebral space, lumbar lordotic angle, operative segmental lordotic angle and fusion rate. The relationship between clinical results and radiology was assessed by comparing the radiological results before and after operation.Results: 99 cases of interbody fusion were performed successfully, and all patients had clinical improvement. The follow-up time was 24-38 months. The operation time, intraoperative blood loss, incision length and hospital stay in OLIF group were significantly less than those in the PLIF group (p<0.05). The intervertebral disc height, lumbar lordotic angle and operative segmental lordotic angle in the two groups were significantly enhanced compared with those before operation, and the difference was statistically significant (p<0.05). All of them achieved satisfactory fusion effect. Complications were found in 5 cases in OLIF group and 13 cases in PLIF group.Conclusion: Both OLIF and PLIF are effective in the treatment of degenerative lumbar diseases. Compared with PLIF, OLIF has a lot advantages in early stage after operation, However, similar clinical outcomes were achieved in the two approaches at mid-term follow-up visit.
Comparison of Two Surgical Approaches for Displaced Intra-Articular Calcaneal Fractures: The Modified Sinus Tarsi Approach Versus The Extensile Lateral Approach
Authors: Ma Chao , Zhao Jiaju , Yi Nan , Zhou Jupu , Zuo Zhicheng , Jiang Bo 
Published: December 2020

Abstract
Background: Displaced intra-articular calcaneal fractures (DIACF) can seriously affect foot function. The conventional surgical approach is the extensile lateral approach (ELA), but it has a high incidence of complications. To reduce the complications associated with ELA, many minimally invasive approaches have been suggested. The purpose of this study was to assess the clinical efficacy and complications of the ELA and a modified sinus tarsi approach (MSTA) for the treatment of DIACF.Methods: One-hundred eight patients (107 feet) with Sanders II~IV calcaneal fractures were retrospectively analysed, including 52 patients (56 feet) in the MSTA group and 56 patients (61 feet) in the ELA group. The functional and radiological results of the affected foot were analysed retrospectively. Functional evaluation included AOFAS, VAS, and SF-36. Radiological evaluation included preoperative and postoperative changes in the Bohler Angle, Gissane Angle, length, width, and height of the calcaneus. The postoperative complications were also collected and analysed. Results: The average AOFAS scores of the MSTA group and the ELA group were 80.57±7.80 and 77.34±8.29 (p=0.033), respectively. The postoperative VAS scores of the MSTA group and the ELA group were 1.66±0.98 and 2.03±0.98 (p=0.043), respectively. The postoperative SF-36-PCS score of the MSTA group was superior to that of the ELA group (77.91±5.03 vs. 74.20±5.07, p<0.000), while there was no significant difference in the SF-36-MCS score (74.84±7.77 vs 72.70±8.21, p=0.153). After surgery, the Bohler Angle, Gissane Angle, and the length, width, and height of the calcaneus were significantly improved in the MSTA group and the ELA group, but there were no statistically significant differences between the two groups. The incidence of wound healing complications in the MSTA group and the ELA group was 5.36% and 14.75% (p < 0.000). Sural nerve injury and subtalar arthritis complications were less common in the MSTA group than in the ELA group (p<0.000).Conclusion: For DIACF, the MSTA was able to achieve similar effects of anatomical reconstruction and postoperative foot function recovery as the ELA, while also effectively reducing the incidence of postoperative sural nerve injury and wound healing complications and shortening the length of hospital stay.
Imitating Hadron Production with PHIT
Authors: Shafigh AmirAbbas Eslami , Davoudifar Pante'a 
Published: December 2020

Abstract
We announce PHIT as a numerical model for simulating of hadroproduction and compare our results with other models and experimental data. Our code, although very simple, imitates the expected results acceptably compared to other more detailed physical models. Moreover, PHIT is fast and easily executable on an ordinary PC. These advantages make PHIT an ideal choice for practical applications of an event generator.
Global Burden of Non-Communicable Diseases Attributable to Dietary Risks in 1990-2019
Authors: Qiao Jie , Lin Xiling , Wu Yiwen , Huang Xin , Pan Xiaowen , Xu Jingya , Wu JunYun , Shan Peng-Fei , Ren Yuezhong 
Published: December 2020

Abstract
Background: Dietary risks raised attention around worldwide during the past decades. The aims of this burden-of-disease study were to evaluate the global dietary risks for non-communicable diseases (NCDs) from 1990 to 2019 and quantify their impact on mortality and disability-adjusted life-years (DALYs). Data from the 2019 Global Burden of Disease Study on deaths and DALYs from NCDs attributable to worldwide dietary risks were obtained and underwent deep analysis by year, age, gender, location, leading risks, and leading causes, and their associations were examined. The Socio-demographic Index (SDI) was used as an indicator of national socioeconomic status, and the relationships between age-standardized rates of deaths or DALYs and socioeconomic status. Results: In 2019, 7.9 million deaths and 187.7 million DALYs were attributable to dietary risk factors. High intake of sodium and low intake of whole grains and fruits were leading dietary risks for deaths and DALYs worldwide. However, both indexes showed a decreasing trend by year, an increase by age, and a higher disease burden in males. The main distribution of dietary-related NCDs was located in highly populated countries. A negative association between the SDI and disease burden, and a positive association between the SDI and male preponderance were found. Conclusions: Dietary risk factors for NCDs increased significantly and varied across regions during 1990-2019. Therefore, greater efforts are needed to raise public awareness of interventions and improve dietary practices to reduce the disease burden caused by suboptimal dietary intake, especially in developing countries and among males.
Impact of Dynamic Capacities on the Performance of Food and Beverage Enterprises in Lagos, Nigeria
Authors: Lin Zhou Lu , Ayegba James Onuche , Onu Emmanuel , James Peace Maina , Jie Zhang Xin 
Published: December 2020

Abstract
This study examined the impact of dynamic capacities on the performance of food and beverage enterprise in Lagos, Nigeria. The following sub-variables (strategic decision-making capacity, product innovation capacity, strategic flexibility, competitive intensity, technological turbulence, and technological capability) were employed to represent the variable of dynamic capacity. Also, the following sub-variables (sales growth, enterprise survival, enterprise efficiency and competitive advantage) were employed to represent the variable of enterprise performance. Primary data was used to achieve descriptive and inferential statistics, and the statistics is estimated by PLS-SEM method which was calibrated on Lisrel 8.70 software.This study found that product innovation, competitive intensity and technological turbulence, technological capability and competitive intensity, and strategic flexibility are critical sub-variables in determining the robustness of dynamic capacities, as they adequately improve increasing sales growth, survival and sustenance of enterprise into the unforeseeable future, efficiency of enterprise, and competitive advantage of food and beverage manufacturing enterprises respectively, particularly in this trying period that is evidenced with technological change, competition, among others.
Response of Potato (Solanum tuberosum L.)&nbsp;to nitrogen and phosphorus fertilizer at Wag-Lasta Areas of Eastern Amhara, Ethiopia
Authors: Sebnie Workat , Esubalew Tilahun , Mengesha Merse 
Published: December 2020

Abstract
Background: Production and productivity of potato in Ethiopia is far below the world average due to soil fertility problem, pest, disease, and agronomic factors. Nutrient depletion due to soil erosion is a serious problem in Ethiopian highlands. Annually, 122 kg ha-1 nitrogen, 13 kg ha-1 phosphorous and 82 kg ha-1 potasium were estimated to deplete from Ethiopia (Haileslassie et al., 2005). The essential nutrients like, nitrogen and phosphorus are the most important influential nutrient for the production of potato but they are deficient in most Ethiopian soils and thus an application of these nutrients could increase significantly the crop yields. In this context, an experiment was conducted at Sekota and Lasta Lalibela districts (Woleh and Kechin Abeba irrigation command areas) of eastern Amhara, Ethiopia to investigate the effects of nitrogen and phosphorus fertilizers for yield and yield component of potato under irrigation condition. Methods: Four rates of nitrogen (0, 46, 92, and 138 kg N kg ha-1) and four rates of phosphorus (0, 23, 46, and 69 Kg P2O5 kg ha-1) were combined in the factorial arrangement and laid out in randomized complete block design with three replications. Results: The result of the study revealed that nitrogen and phosphorus had a significant effect on plant height, marketable, and total yield of potato at Kechin Abeba. But phosphorus did not show a significant effect on plant height and unmarketable yield at Sekota district of Woleh irrigation command area. The highest yield 45.55 t ha-1 was obtained from in combined application of 138 N and 23 P2O5 in Lalibela and 17.12 t ha-1 was obtained from in combined application of 138 N kg ha-1 and 46 P2O5 kg ha-1 from Sekota districts of Woleh irrigation command area. Conclusion: The application of 138 kg ha-1 N with 23 kg ha-1 P2O5 is the appropriate rates for optimum productivity of Potato at Lalibela (Kechin Abeba) and Sekota (Woleh) irrigation schemes and the same agro-ecology.
Sociodemographic and lifestyle correlates of exclusive breastfeeding practices among mothers on antiretroviral therapy in the Eastern Cape, South Africa
Authors: GOON PROF DANIEL TER , Ajayi Anthony Idowu , ADENIYI OLADELE VINCENT 
Published: December 2020

Abstract
Background: Exclusive breastfeeding is associated with a reduction of postnatal HIV transmission and optimal infant growth. Given that the factors influencing exclusive breastfeeding are multi-factorial and context-specific, we examined the prevalence and factors associated with exclusive breastfeeding practice in the first six months among mothers on antiretroviral therapy in the Eastern Cape, South Africa. Methods: This was a prospective cross-sectional study conducted between January – May 2018 on 469 parturient women enlisted in the prevention of mother-to-child HIV transmission cohort study in the Eastern Cape. Exclusive breastfeeding was defined as infant feeding with breast milk only. We collected relevant sociodemographic, lifestyle and maternal information by interview. Bivariate and multivariable logistic regression analyses were fitted to determine the sociodemographic and lifestyle factors associated with exclusive breastfeeding practice.Results: Exclusive breastfeeding for six months was practised by a few women (32.0%). The prevalence of exclusive breastfeeding was significantly higher among married women (36.8%), unemployed women (36.6%), non-smokers (32.7%) and those who never drank alcohol (37.0%). Unemployed women [adjusted odds ratio (AOR) = 1.66, 95% Confidence Interval CI): 1.08-2.56] and those with grade 12 or less level of education (AOR =2.76, 95% CI: 1.02-7.49) had a higher likelihood of practising EBF for six months while mothers who consumed alcohol (AOR = 0.54, 95% CI: 0.34-0.85) were less likely to practice EBF for six months. Conclusions: The prevalence of exclusive breastfeeding in the study, although comparable with sub-Saharan Africa and worldwide prevalence, remain suboptimal. Advocacy campaign on exclusive breastfeeding must target alcohol cessation and the creation of a favourable workplace environment for lactating mothers.
High turnover in clinical dietetics: A qualitative analysis
Authors: Hewko Sarah J , Oyesegun Amirah , Clow Samantha , VanLeeuwen Charlene 
Published: December 2020

Abstract
Background: Relationships between dietitians and other healthcare providers can impact the degree to which patient care is collaborative; inefficient communication can lead to suboptimal care. It takes time for multidisciplinary team members to build collaborative, trusting relationships. For this reason, frequent dietitian turnover is of concern. Consequences include fewer referrals to clinical dietetic services and limited provider continuity. The characteristics of clinical dietetic jobs associated with high turnover have not been identified. We predicted that managers would identify disease prestige as having an impact. In this study, we aimed to explore: 1) characteristics of clinical dietetic jobs associated with the highest turnover, and 2) consequences of high turnover on patients and managers of clinical dietitians. Methods: Research assistants conducted semi-structured interviews with ten managers of clinical dietitians in the Canadian public healthcare system. We employed a constant comparative approach to thematic analysis. We classified themes related to turnover as either avoidable or unavoidable. Results: Sub-themes under avoidable turnover included lack of manager support, growth opportunities, burnout/workload, tension/conflict and hours of work. Sub-themes under unavoidable turnover included life-stage/life-events and geography. We also identified themes related to consequences of turnover, including: burnout/workload, client/patient impact, tension/conflict, cost and gap-specific. As predicted, prestige was perceived as playing a role in triggering dietitian turnover. Managers observed high turnover resulting in low provider continuity and limiting patient access to dietitians. Conclusions: Managers of publicly-employed dietitians identified many factors as contributing to high turnover. Future prospective research, incorporating the objective measure of turnover and multi-method analysis of work characteristics and work setting, would be of value in the identification of characteristics of clinical dietetic jobs associated with high turnover and the consequences of high turnover on patients and managers of these staff.
Endoscopic ultrasound-guided fine-needle aspiration of pelvic lesions via the upper and lower gastrointestinal tract approaches
Authors: Mita Naoki , Iwashita Takuji , Senju Akihiko , Ichikawa Hironao , Iwasa Yuhei , Yasuda Ichiro , Shimizu Masahito 
Published: December 2020

Abstract
Background: Combining upper and lower gastrointestinal tract (GI) approaches allows expansion of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) indications for pelvic lesions. The upper GI approach has been used for pelvic lesions around the level of the aortoiliac bifurcation in our institution. The aim of this study is to evaluate the feasibility and safety of EUS-FNA for pelvic lesions via the upper and lower GI approaches. Methods: All consecutive patients who underwent EUS-FNA for the pelvic lesion between January 2008 and December 2018 were retrospectively analyzed. Pelvic lesions were defined as lesions located around and below the aortoiliac bifurcation level. The primary outcome was technical success rate, and the secondary outcomes were the diagnostic capability of EUS-FNA for malignancy and the safety.Results: EUS-FNA for pelvic lesions was performed in 49 patients: upper and lower GI approaches were used in 28 and 21 patients, respectively. The technical success rates were 91.8% (45/49) in all patients: 89.3% (25/28) and 95.2% (20/21) with the upper and lower GI approaches, respectively. Among patients who achieved technical success, the diagnostic accuracy for malignancy was 97.8% (44/45) in all patients:100% (25/25) and 95.0% (19/20) with the upper and lower GI approaches, respectively. One (2.0%) patient developed an adverse event of sigmoid colon perforation.Conclusions: EUS-FNA for pelvic lesions via the upper and lower GI approaches was a safe, feasible, and effective method, although careful endoscopic manipulation is required to avoid perforation, especially with the lower GI approach. Further large-scale, well-designed studies are needed to validate our findings.