bluuebunny/crossref_metadata_2025_split huggingface dataset:
“You only live twice”: multidisciplinary management of catastrophic case in placenta Accreta Spectrum-a case report
Authors: Atallah David , Abou Zeid Hicham , Moubarak Malak , Moussa Maya , Nassif Nadine , Jebara Victor 
Published: February 2020

Abstract
Background
Placenta percreta is associated with high hemorrhagic risk and can be complicated with fatal thromboembolic events. Involving a multidisciplinary team in the treatment of these patients is mandatory to reduce morbidity and mortality.

Case presentation
This paper reports the case of a 22-year-old patient with placenta percreta who was referred to our tertiary care center for delivery. Few hours after undergoing a successful cesarean hysterectomy, the patient developed a pulmonary embolism and cardiac arrest. A transthoracic echocardiogram done in the intensive care unit (ICU) showed a thrombus in the right ventricle. After cardiac resuscitation, the patient underwent an urgent thoracotomy and a pulmonary artery thrombectomy; many clots were retrieved from the pulmonary artery. After weaning from extracorporeal circulation, an intraoperative transesophageal cardiac ultrasound enabled the medical team to detect a new free-floating thrombus in the right atrium and right ventricle, and consequently to perform an embolectomy and prevent the patient’s death.

Conclusion
This case emphasizes the role of multidisciplinary team in treating high-risk obstetric cases that could be complicated with massive and fatal thromboembolic events. The use of intraoperative transthoracic echocardiography helps in detecting a new thrombus and guides the anesthesiologist in the intra-operative monitoring.
Accuracy of unguided and ultrasound guided Coracohumeral ligament infiltrations – a feasibility cadaveric case series
Authors: Pape John L. , Boudier-Revéret Mathieu , Brismée Jean-Michel , Gilbert Kerry K. , Grabs Detlev , Sobczak Stéphane 
Published: February 2020

Abstract
Background
Coracohumeral ligament (CHL) thickening, contracture, and fibroplasia have been identified in glenohumeral idiopathic adhesive capsulitis (GHIAC). The CHL is the main structure responsible for the range of motion limitations. Favorable outcomes have been reported with CHL surgical release. Intra-articular glenohumeral joint corticosteroid infiltrations are utilized to disrupt the inflammatory process and reduce pain in GHIAC. The aim of this study was to investigate whether the CHL could be accurately targeted with a periligamentous infiltration.

Methods
A convenience sample of 12 unembalmed cadaver shoulders (mean age: 74.5 years, range 66–87 years) without evidence of previous injury or surgery were utilized in this exploratory double factor feasibility cadaveric (unguided and ultrasound (US) guided) case series. Two clinicians trained in musculoskeletal infiltration techniques carried out the infiltrations on each shoulder with colored latex. One clinician infiltrated without guidance, the other with US-guidance. The injecting clinicians were blinded to the others infiltration procedure and the order was randomized. An anatomist blinded to the infiltration order performed a shoulder dissection and recorded the infiltrate location. Percentage calculation for accuracy of infiltration and a chi-square evaluation of the difference between unguided and US-guided infiltrations was applied.

Results
An accuracy of 75% was achieved for unguided infiltration and 80% for US-guided infiltration techniques. Chi-squared indicated there was no significant difference (p = 0.82) between the unguided and US-guided techniques.

Conclusion
US-guided and unguided infiltrations achieved good accuracy targeting the CHL, suggesting infiltrations can specifically and accurately target the CHL. In vivo investigation using such infiltration techniques are warranted.
Role of O-C2 angle in the development of dysphagia in patients with halo-vest fixation
Authors: Miyagi Midori , Takahashi Hiroshi , Tsuchiya Kazuaki , Sekiya Hideki , Ebihara Satoru 
Published: February 2020

Abstract
Background
Dysphagia is one of the most serious complications in patients treated with a halo-vest brace. However, the cause of dysphagia development by halo-vest fixation is not yet clear. We therefore investigated the incidence of dysphagia and cervical alignment as well as clinical data from medical charts in patients treated with a halo-vest brace.

Methods
We retrospectively reviewed clinical data from the medical charts of 49 patients who had undergone halo-vest fixation. Occipito (O)-C2 angle, C2-C6 angle, and pharyngeal inlet angle were assessed by lateral plain X-rays of the cervical spine. The impacts of these parameters on incidence and severity of dysphagia were analyzed.

Results
Thirteen patients (32%) suffered from dysphagia during halo-vest fixation, and age and length of intensive care unit (ICU) stay were greater in the dysphagia group (p = 0.044 and 0.013, respectively) than in those who did not develop dysphagia. O-C2 angle was smaller in the dysphagia group (p = 0.016). After multivariate logistic analysis, body mass index, ICU stay, and O-C2 angle remained as independent risk factors related to incidence of dysphagia. Spearman rank correlation showed a negative correlation between ICU stay and Food Intake Level Scale (FILS) (p = 0.026), and a positive correlation between O-C2 angle and FILS (p = 0.008).

Conclusion
This study suggested that O-C2 angle is related to both incidence and severity of dysphagia due to halo-vest fixation.
A snapshot of microbial diversity and function in an undisturbed sugarcane bagasse pile
Authors: Gebbie Leigh , Dam Tuan Tu , Ainscough Rebecca , Palfreyman Robin , Cao Li , Harrison Mark , O’Hara Ian , Speight Robert 
Published: February 2020

AbstractBackgroundSugarcane bagasse is a major source of lignocellulosic biomass, yet its economic potential is not fully realised. To add value to bagasse, processing is needed to gain access to the embodied recalcitrant biomaterials. When bagasse is stored in piles in the open for long periods it is colonised by microbes originating from the sugarcane, the soil nearby or spores in the environment. For these microorganisms to proliferate they must digest the bagasse to access carbon for growth. The microbial community in bagasse piles is thus a potential resource for the discovery of useful and novel microbes and industrial enzymes. We used culturing and metabarcoding to understand the diversity of microorganisms found in a uniquely undisturbed bagasse storage pile and screened the cultured organisms for fibre-degrading enzymes.ResultsSamples collected from 60 to 80 cm deep in the bagasse pile showed hemicellulose and partial lignin degradation. One hundred and four microbes were cultured from different layers and included a high proportion of oleaginous yeast and biomass-degrading fungi. Overall, 70, 67, 70 and 57% of the microbes showed carboxy-methyl cellulase, xylanase, laccase and peroxidase activity, respectively. These percentages were higher in microbes selectively cultured from deep layers, with all four activities found for 44% of these organisms. Culturing and amplicon sequencing showed that there was less diversity and therefore more selection in the deeper layers, which were dominated by thermophiles and acid tolerant organisms, compared with the top of pile. Amplicon sequencing indicated that novel fungi were present in the pile.ConclusionsA combination of culture-dependent and independent methods was successful in exploring the diversity in the bagasse pile. The variety of species that was found and that are known for biomass degradation shows that the bagasse pile was a valuable selective environment for the identification of new microbes and enzymes with biotechnological potential. In particular, lignin-modifying activities have not been reported previously for many of the species that were identified, suggesting future studies are warranted.
Bioactivity evaluations of leaf extract fractions from young barley grass and correlation with their phytochemical profiles
Authors: Panthi Mamata , Subba Romit Kumar , Raut Bechan , Khanal Dharma Prasad , Koirala Niranjan 
Published: February 2020

AbstractBackgroundThe pressed juice of Barley Grass (BG) has become very popular among people for various assumed benefits along with many testimonies of people who have been healed from various ailments such as anemia, cancer, GI problems by consuming BG. The aim of our research was to validate the claims of its medicinal values such as chemo-protective action, high anti-oxidants, RBC membrane stabilization activity, and toxicity level.MethodsExtracts of hexane, ethyl acetate and methanol were quantitatively estimated for total phenolic contents (TPC) and total flavonoid contents (TFC). The same extracts were assessed for their antioxidative potentials with the use of DPPH free radical scavenging assay followed by determination of HRBC membrane stabilization method, Brine Shrimp Lethality Assay (BSLA) and GC-MS analysis.ResultsAll the extracts showed high TPC and TFC along with the stronger correlation with the antioxidant activity of the extracts suggesting phenolics and flavonoids contents of the extract might be attributed to showing antioxidant activity. The methanolic and ethyl acetate extracts of the plant also showed remarkable anti-inflammatory activity where methanolic extracts had the lowest EC50. During Brine Shrimp Lethality Assay, all extracts of BG were found to be bioactive and the degree of lethality was found to be concentration dependent. The GC-MS analysis of the methanolic extract of BG revealed 23 compounds which are reported to possess different biological activities.ConclusionThe study reveals the strong antioxidant and RBC membrane stabilization activity of BG. The Brine Shrimp Lethality Assay found extracts to be bioactive suggesting extracts as a promising candidate for plant-derived anti-tumor compounds. Further, studies are needed to validate the data on cancer cell lines.
Advancing laboratory medicine in hospitals through health information exchange: a survey of specialist physicians in Canada
Authors: Raymond Louis , Maillet Éric , Trudel Marie-Claude , Marsan Josianne , de Guinea Ana Ortiz , Paré Guy 
Published: February 2020

Abstract
Background
Laboratory testing occupies a prominent place in health care. Information technology systems have the potential to empower laboratory experts and to enhance the interpretation of test results in order to better support physicians in their quest for better and safer patient care. This study sought to develop a better understanding of which laboratory information exchange (LIE) systems and features specialist physicians are using in hospital settings to consult their patients’ laboratory test results, and what benefit they derive from such use.

Methods
As part of a broader research program on the use of health information exchange systems for laboratory medicine in Quebec, Canada, this study was designed as on online survey. Our sample is composed of 566 specialist physicians working in hospital settings, out of the 1512 physicians who responded to the survey (response rate of 17%). Respondents are representative of the targeted population of specialist physicians in terms of gender, age and hospital location.

Results
We first observed that 80% of the surveyed physicians used the province-wide interoperable electronic health records (iEHR) system and 93% used a laboratory results viewer (LRV) to consult laboratory test results and most (72%) use both systems to retrieve lab results. Next, our findings reveal important differences in the capabilities available in each type of system and in the use of these capabilities. Third, there are differences in the nature of the perceived benefits obtained from the use of each of these two systems. Last, the extent of use of an LRV is strongly influenced by the IT artefact itself (i.e., the hospital’s LRV available capabilities) while the use of the provincial iEHR system is influenced by its organizational context (i.e. the hospital’s size and location).

Conclusions
The main contribution of this study lies in its insights into the role played by context in shaping physicians’ choices about which laboratory information exchange systems to adopt and which features to use, and the different perceptions they have about benefits arising from such use. One related implication for practice is that success of LIE initiatives should not be solely assessed with basic usage statistics.
Cold beverage-induced vasovagal syncope in a healthy young adult man: a case report
Authors: Arandjelović Ognjen 
Published: February 2020

Abstract
Background
Swallowing-induced syncope is rare and there are few case reports of it in the existing medical literature. Even rarer are instances involving young and healthy individuals, with no existing pre-conditions or apparent risk factors. Hence the value of such case reports in understanding the phenomenon better and potentially inferring patterns of practical interest is significant; here we describe an unusual case of a swallowing-induced syncope in a young, healthy, and active white man.

Case presentation
A healthy 32-year-old white man experienced a syncopal episode following the ingestion of a cold carbonated beverage on a hot day. He rapidly recovered consciousness and save for mild lightheadedness all ill effects disappeared within minutes. On examination no concerns were detected and he was discharged, with the cause being ascribed to esophageal stimulation effected vagus nerve overactivation.

Conclusions
The suddenness and unpredictability of swallowing-induced syncope make it a potentially dangerous condition, with risks both to the patient as well as, depending on the context, others. However, it is poorly understood due to its infrequency. The present case report adds to the body of much needed evidence which should help facilitate an improved understanding of the phenomenon.
A new class of travelling wave solutions for local fractional diffusion differential equations
Authors: Shi Ziyue , Qi Wei , Fan Jing 
Published: February 2020

AbstractIn this paper, we investigate a 3-D diffusion equation within the scope of the local fractional derivative. For this model, we establish local fractional vector operators and a local fractional Laplace operator defined on Cantor-type cylindrical coordinate and Cantor-type spherical coordinate, respectively. With the help of the spherical symmetry method based on those operators, we obtain exact traveling wave solutions of the 3-D diffusion equation. The results reveal that the proposed schemes are very effective for obtaining nondifferentiable solutions of fractional diffusion problems.
Morphology and features of Cambrian oncoids and responses to palaeogeography of the North China Platform
Authors: Xiao En-Zhao , Mei Ming-Xiang , Jiang Shu , Zafar Tehseen 
Published: February 2020

AbstractThe Cambrian strata in the North China Platform are fully exposed. A wide variety of carbonate oncoids with different shapes occur in the Xuzhuang and Zhangxia formations (Miaolingian Series) from six Cambrian sections in the study area. A comprehensive study involving outcrop description, microscopic observation, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and carbon and oxygen isotope analysis is conducted to determine the facies, morphology, internal structure, and geochemical properties of the oncoids. The oncoids are divided into six types based on their morphology and internal structure. Microscopic and ultrastructural observations reveal typical microbial fossils (Girvanella) and microbially-related sediments (framboidal pyrite), indicating the biogenicity of the oncoids. Additionally, the XRD and carbon and oxygen isotope analysis results suggest that the formational environments of these oncoids are different due to terrestrial influences. Statistical data on the oncoids from the six sections show that there are obvious differences in the types of oncoids and the proportions of different varieties in each section. The spatial differences in the oncoid morphologies are associated with different palaeogeographic settings. The rough oncoid growth patterns developed in nearshore environments were influenced by terrigenous debris and steep terrain, whereas the delicate oncoid growth patterns developed in offshore environments were less affected by terrestrial factors and were featured by more stable depositional processes related to microbial mats.
Extent and Predictors of Delays in Diagnosis of Cervical Cancer in Addis Ababa, Ethiopia: A Population-Based Prospective Study
Authors: Dereje Nebiyu , Addissie Adamu , Worku Alemayehu , Assefa Mathewos , Abraha Aynalem , Tigeneh Wondemagegnehu , Kantelhardt Eva Johanna , Jemal Ahmedin 
Published: February 2020

PURPOSE A substantial proportion of cervical cancers are diagnosed at advanced stage in Ethiopia. Therefore, the aim of this study was to determine the extent and predictors of delays in cervical cancer diagnosis in Addis Ababa. PATIENTS AND METHODS We prospectively recruited 231 patients with cervical cancer diagnosed from January 1, 2017, to June 30, 2018, in 7 health facilities in Addis Ababa, representing 99% of all cervical cancers recorded in the Addis Ababa population-based cancer registry. A structured questionnaire on patients’ experience was administered face to face by trained interviewers. Health-seeking intervals > 90 days (date from recognition of symptoms to medical consultation) and diagnostic intervals > 30 days (dates from medical consultation to diagnostic confirmation) were categorized as delayed. Factors associated with these delays were assessed using multivariable binary logistic regression models. RESULTS The median health-seeking and diagnostic intervals for patients with cervical cancer in Addis Ababa were 10 and 97 days, respectively. Approximately one quarter of the patients were delayed in seeking medical consultation, and three fourths of the patients had delayed diagnostic confirmation. Factors associated with health-seeking delays included poor cervical cancer awareness, practicing of religious rituals, and waiting for additional symptoms before visiting a health facility. Factors associated with diagnostic delays included first contact with primary health care units and visits to ≥ 4 different health facilities before diagnosis. CONCLUSION A considerable proportion of patients with cervical cancer in Addis Ababa have delays in seeking medical care and diagnostic conformation. These findings reinforce the need for programs to enhance awareness about cervical cancer signs and symptoms and the importance of early diagnosis in the community and among health care providers.
Adapting the “Resist Diabetes” Resistance Training Intervention for Veterans
Authors: VanDerBrink Emily , Boshra Soheir , Harden Samantha M. , Oursler Kris Ann K. , Winett Richard , Davy Brenda 
Published: February 2020

ABSTRACT

Purpose
The Resist Diabetes (RD) trial demonstrated that twice-per-week resistance training reduced prediabetes prevalence and improved strength among older adults with prediabetes. Our objectives were to determine initial perceptions of patients and care providers in a Veterans Affairs Medical Center (VAMC) regarding RD and ultimately to inform adaptations to improve uptake of RD in the Veterans Health Administration.

Methods
A mixed-methods approach was utilized. Care providers (n = 20) and veterans with prediabetes (n = 12) were recruited to gauge perceptions of the RD program and identify barriers and facilitators to the program referral process and program implementation. Care provider perceptions of the acceptability, appropriateness, and feasibility were determined using a validated survey. Open-ended questionnaires and interview guides, based on the Consolidated Framework for Implementation Research, were utilized to determine major and minor themes within the provider and veteran responses. To identify the dissemination potential of RD, the availability of onsite fitness facilities at VAMC facilities nationally (n = 159) was assessed.

Results
Providers rated (scaled 1–5: 1, completely disagree; 5, completely agree) the RD program as appealing (4.8 ± 0.1), appropriate (4.8 ± 0.0), and feasible (4.6 ± 0.2). Providers reported that prediabetes/diabetes is a significant problem in the VAMC, and that different prevention programs will appeal to different types of VAMC patients. Patients (n = 12 [58% female]; aged 65 ± 10 y; body mass index, 34 ± 6 kg·m−2; hemoglobin A1C, 5.7% ± 1.8%) expressed interest in an exercise-focused diabetes prevention program and defined key barriers: travel, transportation, and time constraints. Among the responding national VAMC sites, 85% (97/114) reported having an onsite fitness facility.

Conclusion
Salem VAMC care providers and veteran patients demonstrated positive perceptions of the RD program. Program adaptations are needed to address barriers to patient participation including travel, transportation, and time constraints.
Patterns of synthetic cathinones use and their impact on depressive symptoms and parafunctional oral behaviors
Authors: Więckiewicz Gniewko , Smardz Joanna , Wieczorek Tomasz , Rymaszewska Joanna , Grychowska Natalia , Danel Dariusz , Więckiewicz Mieszko 
Published: February 2020

Cel pracySyntetyczne katynony (znane również jako "sole do kąpieli") to nowe substancje psychoaktywne wprowadzone na rynek globalny w ciągu ostatnich 10 lat jako zamienniki nielegalnej amfetaminy. Ze względu na łatwą dostępność szybko stały się popularne. Celem pracy było określenie związku stosowania syntetycznych katynonów z objawami depresyjnymi i zachowaniami ustnymi wśród użytkowników rekreacyjnych.MetodaUżytkownicy forów internetowych związanych z narkotykami zostali poproszeni o wypełnienie ankiety za pośrednictwem platformy Google Forms. Kwestionariusz zawierał pytania dotyczące schematów używania środków psychoaktywnych, Inwentarz Depresji Becka II (BDI II) oraz Kwestionariusz Zachowań Ustnych (OBC) oraz podstawowe dane demograficzne (wiek, płeć).Wyniki150 uczestników (75 w grupie badanej, 75 w grupie kontrolnej) wzięło udział w badaniu. W grupie badanej (w wieku od 15 do 28 lat) wszyscy uczestnicy korzystali z katynonów i innych substancji psychoaktywnych. 42 respondentów korzystało z katynonów w ciągu ostatniego miesiąca. Analiza statystyczna wykazała korelację między liczbą zażywanych substancji psychoaktywnych i poziomem depresji w obu grupach (badanej i kontrolnej), a także statystycznie istotnie wyższą średnią wartościąwyników OBC w grupie użytkowników katynonów w porównaniu z grupą kontrolną. Korelacja między depresją a OBC była statystycznie istotna zarówno dla grupy badanej, jak i kontrolnej.WnioskiBiorąc pod uwagę łatwy dostęp do syntetycznych katynonów, częste zatrucia i młody wiek użytkowników tego badania, temat powinien zostać szerzej przebadany. Substancje psychoaktywne mogą predysponować do rozwoju depresji i różnych form parafunkcyjnych zachowań ustnych.