bluuebunny/crossref_metadata_2025_split huggingface dataset:
Double-pulse speckle contrast correlations with near Fourier transform limited free-electron laser light using hard X-ray split-and-delay
Authors: Roseker Wojciech , Lee Sooheyong , Walther Michael , Lehmkühler Felix , Hankiewicz Birgit , Rysov Rustam , Hruszkewycz Stephan O. , Stephenson G. Brian , Sutton Mark , Fuoss Paul H. , Sikorski Marcin , Robert Aymeric , Song Sanghoon , Grübel Gerhard 
Published: March 2020

AbstractThe ability to deliver two coherent X-ray pulses with precise time-delays ranging from a few femtoseconds to nanoseconds enables critical capabilities of probing ultra-fast phenomena in condensed matter systems at X-ray free electron laser (FEL) sources. Recent progress made in the hard X-ray split-and-delay optics developments now brings a very promising prospect for resolving atomic-scale motions that were not accessible by previous time-resolved techniques. Here, we report on characterizing the spatial and temporal coherence properties of the hard X-ray FEL beam after propagating through split-and-delay optics. Speckle contrast analysis of small-angle scattering measurements from nanoparticles reveals well-preserved transverse coherence of the beam. Measuring intensity fluctuations from successive X-ray pulses also reveals that only single or double temporal modes remain in the transmitted beam, corresponding to nearly Fourier transform limited pulses.
Quality Evaluation of Corydalis yanhusuo by High-Performance Liquid Chromatography Fingerprinting Coupled with Multicomponent Quantitative Analysis
Authors: Lu Yin , Ma Qin , Fu Changchun , Chen Chuan , Zhang Deyong 
Published: March 2020

AbstractCorydalis Rhizoma is the tuber of Corydalis yanhusuo W. T. Wang, which has been long used in traditional Chinese medicine. Herein, the quality of C. yanhusuo samples collected from 23 regions of three provinces in China is evaluated through high-performance liquid chromatography fingerprinting coupled with similarity, hierarchical clustering, and principal component analyses. Sample similarities are evaluated according to the State Food and Drug Administration requirements by selection of 18 characteristic chromatographic fingerprint peaks and are found to vary between 0.455 and 0.999. Moreover, common patterns of a typical local variety of C. yanhusuo sourced in the Panan County are established. The obtained results show that the combination of quantitative analysis and chromatographic fingerprint analysis can be readily utilized for quality control purposes, offering a comprehensive strategy for quality evaluation of C. yanhusuo and related products.
Exceptionally preserved asphaltic coprolites expand the spatiotemporal range of a North American paleoecological proxy
Authors: Mychajliw Alexis M. , Rice Karin A. , Tewksbury Laura R. , Southon John R. , Lindsey Emily L. 
Published: March 2020

AbstractAs fossilized feces, coprolites represent direct evidence of animal behavior captured in the fossil record. They encapsulate past ecological interactions between a consumer and its prey and, when they contain plant material, can also guide paleoenvironmental reconstructions. Here we describe the first coprolites from the lagerstätte Rancho La Brea (RLB) in Los Angeles, California, which also represent the first confirmed coprolites from an asphaltic (“tar pit”) context globally. Combining multiple lines of evidence, including radiocarbon dating, body size reconstructions, stable isotope analysis, scanning electron microscopy, and sediment analyses, we document hundreds of rodent coprolites found in association with plant material, and tentatively assign them to the woodrat genusNeotoma.Neotomanests (i.e., middens) and their associated coprolites inform paleoclimatic reconstructions for the arid southwestern US but are not typically preserved in coastal areas due to environmental and physiological characteristics. The serendipitous activity of an asphalt seep preserved coprolites and their original cellulosic material for 50,000 years at RLB, yielding a snapshot of coastal California during Marine Isotope Stage 3. This discovery augments the proxies available at an already critical fossil locality and highlights the potential for more comprehensive paleoenvironmental analyses at other asphaltic localities globally.
Overexpression of V-type H+ pyrophosphatase gene EdVP1 from Elymus dahuricus increases yield and potassium uptake of transgenic wheat under low potassium conditions
Authors: Zhou Yongbin , Li Yan , Qi Xueli , Liu Rongbang , Dong Jianhui , Jing Weihuan , Guo Mengmeng , Si Qinglin , Xu Zhaoshi , Li Liancheng , Wang Chengshe , Cheng Xianguo , Ma Youzhi , Chen Ming 
Published: March 2020

AbstractLack of potassium in soil limits crop yield. Increasing yield and conserving potassium ore requires improving K use efficiency (KUE). Many genes influence KUE in plants, but it is not clear how these genes function in the field. We identified the V-type H+-pyrophosphatase gene EdVP1 from Elymus dahurica. Gene expression analysis showed that EdVP1 was induced by low potassium stress. Protein subcellular localization analysis demonstrated that EdVP1 localized on the plasma membrane. We overexpressed EdVP1 in two wheat varieties and conducted K tolerance experiments across years. Yield per plant, grain number per spike, plant height, and K uptake of four transgenic wheat lines increased significantly compared with WT; results from two consecutive years showed that EdVP1 significantly increased yield and KUE of transgenic wheat. Pot experiments showed that transgenic plants had significantly longer shoots and roots, and higher K accumulation in shoots and roots and H+-PPase activity in shoots than WT under low K. A fluidity assay of potassium ion in EdVP1 transgenic plant roots showed that potassium ion influx and H+ outflow in transgenic plants were higher than WT. Overexpressing EdVP1 significantly improved yield and KUE of transgenic wheat and was related to higher K uptake capacity in root.
Unexplored features of Ru(ii) polypyridyl complexes – towards combined cytotoxic and antimetastatic activity
Authors: Gurgul Ilona , Mazuryk Olga , Łomzik Michał , Gros Philippe C , Rutkowska-Zbik Dorota , Brindell Małgorzata 
Published: March 2020

Abstract
The well-documented cytotoxic activity of coordinatively saturated and substitutionally inert polypyridyl Ru(ii) complexes substantiates their high potency as antiproliferative agents against primary tumors. However, the primary cause of cancer morbidity and mortality responsible for about 90% of cancer deaths is the occurrence of metastasis. Therefore, scientists have to concentrate their efforts on designing compounds affecting not only the primary tumor, but also efficiently inhibiting metastasis. Herein, we report two families of Ru(ii) polypyridyl complexes bearing 2,2′-bipyridine substituted by a semicarbazone 2-formylopyridine moiety as one of the ligands and 4,4′-di-tert-butyl-2,2′-dipyridyl or 4,7-diphenyl-1,10-phenanthroline as auxiliary ligands. These complexes strengthen cells’ adherent properties and inhibit the activity of metalloproteinases (MMPs) in vitro, which is relevant in anti-metastatic treatment. The in vitro studies were performed on human lung adenocarcinoma (A549) and human pancreatic cancer (PANC-1) cells, which have a well-documented invasive potential. The induced alteration of the tumor cells’ adhesion properties correlated with the high cytotoxic effect exerted by the complexes and their excellent cellular uptake. It was also proved that both complexes directly inhibit M-MP2 and M-MP9 enzyme activities, which are essential for the development of tumor metastasis. The results of this study indicate that the biological properties of polypyridyl Ru(ii) complexes extend beyond the standard cytotoxic activity and represent an important step towards designing new anti-metastatic agents.
Videoconference Administration of the Western Aphasia Battery–Revised: Feasibility and Validity
Authors: Dekhtyar Maria , Braun Emily J. , Billot Anne , Foo Lindsey , Kiran Swathi 
Published: March 2020

Purpose
There is a rapid growth of telepractice in both clinical and research settings; however, the literature validating translation of traditional methods of assessments and interventions to valid remote videoconference administrations is limited. This is especially true in the field of speech-language pathology where assessments of language and communication can be easily conducted via remote administration. The aim of this study was to validate videoconference administration of the Western Aphasia Battery–Revised (WAB-R).

Method
Twenty adults with chronic aphasia completed the assessment both in person and via videoconference with the order counterbalanced across administrations. Specific modifications to select WAB-R subtests were made to accommodate interaction by computer and Internet.

Results
Results revealed that the two methods of administration were highly correlated and showed no difference in domain scores. Additionally, most participants endorsed being mostly or very satisfied with the videoconference administration.

Conclusion
These findings suggest that administration of the WAB-R in person and via videoconference may be used interchangeably in this patient population. Modifications and guidelines are provided to ensure reproducibility and access to other clinicians and scientists interested in remote administration of the WAB-R.

Supplemental Material

https://doi.org/10.23641/asha.11977857
Revisiting the Role of Augmentative and Alternative Communication in Aphasia Rehabilitation
Authors: Dietz Aimee , Wallace Sarah E. , Weissling Kristy 
Published: March 2020

Purpose
The purpose of this article is to revisit the role of augmentative and alternative communication (AAC) in poststroke aphasia rehabilitation. The authors' intent is to provide a viewpoint that expands the use of AAC in poststroke aphasia rehabilitation. Specifically, we seek to clarify the role of AAC in restorative and participation approaches to aphasia rehabilitation while also considering the role of AAC in a comprehensive treatment plan. The authors support their viewpoint with citations from both the historic and contemporary literature on aphasia rehabilitation.

Conclusions
A thought-provoking viewpoint on the role of AAC in poststroke aphasia rehabilitation is proposed. More specifically, the versatility of AAC strategies is reviewed, with an emphasis on how AAC can be used to empower people with aphasia to fully participate and engage in life activities with increased independence. Moreover, we argue that AAC can be viewed as a dual-purpose tool that can simultaneously serve to drive intersystemic reorganization resulting in some improved language performance—and perhaps restoration of language function—while offering a communication alternative during inevitable anomic events.
Respiratory–Swallow Coordination in Healthy Adults During Drinking of Thin to Extremely Thick Liquids: A Research Note
Authors: Valenzano Teresa J. , Guida Brittany T. , Peladeau-Pigeon Melanie , Steele Catriona M. 
Published: March 2020

PurposeRespiratory–swallow coordination is vital for airway protection, preventing aspiration, or penetration of foreign material into the airway. With the implementation of the International Dysphagia Diet Standardization Initiative definitions for different liquid consistencies used in dysphagia management, it is important to establish whether respiratory–swallow coordination patterns differ across these consistencies. This study aimed to evaluate respiratory behaviors during swallowing across the spectrum from thin to extremely thick liquids in healthy adults less than 60 years of age.MethodThirty healthy adults, aged 21–55 years, each consumed 54 naturally sized cup sips or spoonfuls of liquid stimuli prepared in thin, slightly thick, mildly thick, moderately thick, and extremely thick consistencies. Half of the stimuli were prepared using barium and half with a lemon-flavored water. Concurrent respiratory and swallowing pressure signals were collected to evaluate the respiratory phase pattern and pause duration associated with the swallow.ResultsAn expiration–swallow–expiration pattern was the dominant respiratory phase pattern, observed in 92.7% of the trials, with no significant effect of consistency. Respiratory pause duration was found to be significantly shorter with barium stimuli (0.73 s) compared to nonbarium stimuli (0.78 s) (p< .001, Cohen'sd= .2), with no notable effects based on the factors of sex or liquid consistency.ConclusionsIn a convenience sample of healthy adults under the age of 60 years, consistent respiratory–swallow phasing and stable timing across the spectrum from thin to extremely thick liquids was observed. The data from this study can serve as preliminary reference data to which assessment information for individuals with dysphagia or respiratory challenges can be compared.
Examination of Narrative Language at Microstructural and Macrostructural Levels in Spanish-Speaking Preschoolers
Authors: Orizaba Lorena , Gorman Brenda K. , Fiestas Christine E. , Bingham Gary E. , Terry Nicole Patton 
Published: March 2020

Purpose
The purpose of this study was to examine narrative language samples of Spanish-speaking preschoolers to analyze changes in microstructural and macrostructural skills in their first language (L1) from fall to spring, relationships between narrative and vocabulary skills in L1, and the extent to which fall skills predict spring performance.

Method
Participants included 40 Spanish-speaking children who were enrolled in community-based preschool programs. Narrative language retells from the fall and spring were examined, and microstructural and macrostructural components were analyzed using the Narrative Assessment Protocol–Spanish and the Narrative Scoring Scheme, respectively. Participants also completed an assessment of expressive vocabulary in Spanish.

Results
The results indicated different degrees of change in microstructural and macrostructural elements, change from fall to spring in some but not all elements measured, shifting patterns of association between L1 vocabulary and narrative skills, and variable prediction of spring scores.

Conclusion
Results from this study enhance professionals' understanding of Spanish-speaking preschoolers' narrative language skills in L1 and considerations for assessing and monitoring progress at different points in the academic year.
Ambulant erworbene Pneumonie bei Erwachsenen
Authors: Mikolajewska Agata , Witzenrath Martin 
Published: March 2020

AbstractCommunity-acquired pneumonia (CAP) is one of the most common infectious diseases worldwide. To reduce the high morbidity and mortality of CAP, appropriate diagnosis, risk stratification and therapy are necessary. This review summarizes the current recommendations for the management of CAP in Germany. CAP is often a medical emergency. The management of a CAP is based on the individual patient risk. The DS-CRB-65 Score and ATS/IDSA major and minor criteria are well suited for risk stratification. The initially calculated antibiotic therapy is based on the expected spectrum of pathogens and should be adjusted as necessary. Antibiotic therapy is usually administered intravenously in inpatients. With oral therapy, the bioavailability of the antibiotic should be considered. A reevaluation in the first 48–72 hours is mandatory. A therapy duration of 5–7 days is usually sufficient. Preventive influenza and pneumococcal vaccination and nicotine withdrawal are important.
Controversies in Cleft Rhinoplasty
Authors: Hoshal Steven G. , Solis Roberto N. , Tollefson Travis T. 
Published: March 2020

AbstractRhinoplasty for cleft lip nasal deformities challenges all cleft surgeons. There is great variability of phenotypical anatomy, but iatrogenic changes and scarring from the previous surgeries add another layer of complexity. Rhinoplasties on a patient with cleft lip–palate are technically and intellectually challenging to master requiring a patient-tailored approach. The shape and structure of the nose are changed to improve both function and aesthetic appearance. In the primary setting, nasoalveolar molding is a form of presurgical infant orthopaedics used for preparation before the cleft lip and nose repair. Intermediate stages should be conservative to minimize scarring, while the definitive cleft rhinoplasty utilizes cartilage grafts from septum, ear, or rib to sculpt the nose. Hereinto, we will outline the controversies, the evidence supporting certain techniques, and our preferences.
Revision Rhinoplasty: Conservation versus Deconstruction
Authors: Lu G. Nina , Papel Ira D. 
Published: March 2020

AbstractRevision rhinoplasty requires the surgeon to strike a careful balance between conservation and deconstruction. Contemporary rhinoplasty has focused on structural cartilage grafts. These grafts resist static and dynamic forces produced by tissue contraction, gravity, and pressure gradients during respiration. However, the simultaneous use of multiple grafts also leads to an increased deconstruction of natural supports. In this article, we discuss some simple yet effective techniques in revision rhinoplasty in a case-based format.
The African Rhinoplasty
Authors: Boahene Kofi D.O. 
Published: March 2020

AbstractAcross ethnicities, patients seeking rhinoplasty have similar goals—a natural looking nose that fits and complements the rest of their facial features. Beyond a harmonious nose, patients of African descent have a particularly strong desire for ethnically congruent results in spite of individual aesthetic rhinoplasty preferences. This strong appeal for ethnically sensitive alterations is fueled by the desire to maintain physical identification with one's African ethnicity. There are psychosocial penalties when rhinoplasty outcomes stray toward complete racial transformation. Consequently, rhinoplasty in patients of African descent requires a fundamental understanding of acceptable beauty norms, associated psychological underpinnings, as well as unique facial and nasal features among Africans. Beyond these ethnically sensitive nuances, classic rhinoplasty techniques of framework modification with cartilage contouring, grafting, and bone remodeling are applicable in reshaping the African nose.
Local infimum and a family of maximum principles in optimal control
Authors: Avakov E. R. , Magaril-Il’yaev G. G. 
Published: March 2020

Abstract
The notion of a local infimum for the optimal control problem, which generalizes the notion of an optimal trajectory, is introduced. For a local infimum the existence theorem is proved and necessary conditions in the form of a family of ‘maximum principles’ are derived. The meaningfulness of the necessary conditions, which generalize and strengthen Pontryagin’s maximum principle, is illustrated by examples.
Bibliography: 9 titles.
Evolution of dispersal in a spatially heterogeneous population with finite patch sizes
Authors: Parvinen Kalle , Ohtsuki Hisashi , Wakano Joe Yuichiro 
Published: March 2020

SignificanceOrganisms are known to invest resources to disperse their offspring. Plants produce fruits, although fruit eaters do not promise to disperse seeds to the right places. According to a classical theory, costly dispersal can evolve because dispersing individuals can avoid competition among their own offspring. The textbook formulas of evolutionary stable dispersal strategies, however, assume the same living conditions everywhere. Here we present formulas predicting the dispersal probability in spatially heterogeneous environments. In the real world, no environment is homogeneous as assumed in the classical theory, so our results bring in important achievements. In heterogeneous environments the evolved dispersal probability can be much lower than in homogeneous ones, and also diversification in dispersal strategies is possible.
Metabolic control analysis of hepatic glycogen synthesis in vivo
Authors: Nozaki Yuichi , Petersen Max C. , Zhang Dongyan , Vatner Daniel F. , Perry Rachel J. , Abulizi Abudukadier , Haedersdal Sofie , Zhang Xian-Man , Butrico Gina M. , Samuel Varman T. , Mason Graeme F. , Cline Gary W. , Petersen Kitt F. , Rothman Douglas L. , Shulman Gerald I. 
Published: March 2020

Significance
Hepatic glycogen synthesis plays a critical role in maintaining normal glucose homeostasis; however, the rate-controlling step regulating this process is unknown. Applying metabolic control analysis in vivo, we show that the regulation of insulin-stimulated hepatic glycogen synthesis under both normal and pathophysiological conditions of fatty liver-associated hepatic insulin resistance is controlled at the glucokinase (GCK) step through GCK translocation.
Non-degree equatives and reanalysis
Authors: Bacskai-Atkari Julia 
Published: March 2020

Abstract
The article examines reanalysis processes underlying doubling patterns in non-degree equatives in German and Hungarian. In
German, the combination als wie (lit. ‘as how’) is attested historically and in certain present-day dialects.
Traditionally, it is assumed to be a mixed pattern involving the earlier canonical equative complementiser
als and the later canonical equative complementiser wie; however, more recent proposals
suggest that als was in fact reanalysed from the matrix clause. While matrix equative markers and equative
complementisers are surface-similar in German historically, these elements are distinct in Hungarian throughout its history.
Based on the results of a corpus study on Old Hungarian, the paper argues that reanalysis from the matrix clause is indeed
possible and starts in non-degree equatives.
Contextual triggers of the Hungarian pre-verbal focus structure
Authors: Káldi Tamás , Madarász Levente , Babarczy Anna 
Published: March 2020

Abstract
The study uses a novel experimental method to investigate contextual factors claimed in the theoretical literature to license
the use of Hungarian pre-verbal focus. These factors are: (i) identification, (ii) contrast, (iii) availability of a set on
which the focus operates and (iv) whether this set is explicit or implicit. We tested the effects of these factors using
online surveys in which respondents read short texts describing a context and saw a cloud of randomly arranged words. The
experimental task was to create sentences that naturally fit the context by clicking the words in the cloud. Results show that
narrow identification and contrast reliably predict the use of pre-verbal focus as does the availability of a set regardless
of explicitness.
Object agreement and locality in Hungarian
Authors: Szécsényi Krisztina , Szécsényi Tibor 
Published: March 2020

Abstract
The paper claims that the two types of object agreement in Hungarian, definiteness agreement and the special
lak-agreement form used for the combination of first person singular subject and second person object arguments, are
the result of different syntactic operations. The argumentation is based on the different distribution of the two agreement
types. To diagnose the nature of the conditions for agreement we use infinitival embedded clauses, at times with multiple
embedded constructions. Six different patterns are discussed showing sensitivity to locality. Definiteness agreement turns out
to be more restricted than lak-agreement. While the condition for definiteness agreement is the availability of a
position where accusative case can be checked, we claim that no such condition holds for lak-agreement.