bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Short Term Clinical Outcome of Provisional versus Routine Kissing Balloon Technique after Main Vessel Crossover Stenting for Coronary Bifurcation Lesions
Authors: Khalil Mohamed Ahmed , Elsheshtawy Fatehia Ahmed , Ashmawy Medhat Mohamed , El-Din Samiah Mahmoud Sharaf , Elsaeed Ayman Mohamed 
Published: July 2020

Background: Kissing Balloon Inflation (KBI) technique was the first technique for percutaneous intervention in bifurcation lesions. It's the standard strategy in the two-stent procedure. Its benefit in one-stent approach remains uncertain. Several trials comparing KBI strategy with the No-KBI strategy in one-stent technique did not show any advantages in the clinical outcome. Clinical outcome and the follow up of ischemic symptoms is a useful method to compare the effectiveness of both strategies.
Aims: To study the short-term clinical outcome (3and 6 months) of provisional versus routine kissing‑balloon technique after main vessel stenting for coronary bifurcation lesions.
Patients and Methods: The study included sixty consecutive patients. They were randomized to receive different side branch (SB) intervention strategies: group I (provisional final kissing balloon inflation group - PFKBI) (FKBI only when SB Flow less than TIMI 3) and group II (routine final kissing balloon inflation group – RFKBI).
Results: 1- Dissection of side branch and conversion to two stent strategy was significantly higher in PFKBI group (14,3%) than in RFKBI group (0) 2-The amount of dye, total procedure time and time of admission was significantly higher in RFKBI group. 3-Chest pain immediately after the procedure was significantly higher in PFKBI group while at 3 and 6 months follow up no significant difference between both groups was noticed. 4- MACE, target lesion revascularization (TLR) and stent thrombosis were similar between both groups at 3 and 6 months.
Conclusions: Main vessel stenting with and without final kissing balloon dilatation was associated with favorable and similar 3 and 6-month clinical outcomes.
COVID-19, Various Treatment Options and Special Considerations for Dentistry
Authors: Bhardwaj Smita Singh , Alduwayhi Sami , Bhardwaj Atul 
Published: July 2020

Objective: The aim of this article is to analyze the epidemiology of COVID-19, comparison of routes of transmission in children and adults, comparing the clinical symptoms in adults and children, treatment protocol to be followed and possible treatment options during this pandemic. Data Sources: Data is collected from Pubmed, Medline and Embase databases.
Discussion from Previous References Used: Few studies have been done to analyze its effect on children comparing the symptoms of adults and children. Also very less work is done to analyze the special precautions taken while doing dental treatment during this pandemic.
Conclusion: The widespread effect of Coronavirus (COVID-19) or SARS-CoV-2 has created health concerns in the world. Although efforts have been taken to control the disease, it is still increasing due to the community spread. Health professionals may get patients in their practice with this infection and should prevent its spread.
Clinical Significance of this Article: It will help us to differentiate the specific clinical symptoms of adult and pediatric patients coming to dental clinics and the special considerations for them including the emergency dental treatment during COVID-19.
The Effect of Anti-Tubercular Drugs on Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography
Authors: Singh Punit Kumar , Prasnnta . 
Published: July 2020

Purpose: To study the effect of anti-tubercular drugs on retinal nerve fiber layer (RNFL) thickness using optical coherence tomography.
Methods: The study was done in thirty patients newly diagnosed with pulmonary tuberculosis which were given anti-tubercular treatment (isoniazid, rifampicin, ethambutol and pyrazinamide ) at DOTS centre of K. N. TB and Chest hospital (Dr. S.N M C.) Jodhpur. Visual function tests (visual acuity, contrast sensitivity, color vision) and OCT assessment of RNFL done before initiation of treatment and after two month of treatment.
Results: After two months, RNFL thinning was present in 3 eyes out of total 60 eyes in temporal and superior quadrant.
Conclusion: The study revealed that the first line antitubercular drug Ethambutol causes RNFL thinning within two months of initiation of drug in the recomonded dose. In the initial stage of optic nerve toxicity, there are no clinically significant changes seen on posterior segment ophthalmoscopic examination and fundus photography.OCT can find out the retinal nerve fiber layer thinning even if there are minute changes.
Implementation and validation of an in‐house geometry optimization software for SRS VMAT planning of multiple cranial metastases
Authors: Kuo LiCheng , Zhang PengPeng , Pham Hai , Ballangrud Åse M. 
Published: July 2020

AbstractPurposeThe implementation and evaluation of an in‐house developed geometry optimization (GO) software are described. The GO script provides optimal lesion clustering, isocenter placement, and collimator angle of each arc for cranial multi‐lesion stereotactic radiosurgery (SRS) volumetric modulated arc therapy (VMAT) planning.Materials and methodsAn Eclipse‐plugin program was developed to facilitate automatic plan geometry generation for multiple metastases SRS VMAT plans. A mixed, semi‐supervised exhaustive and k‐means clustering method is used to group lesions and place isocenters. The sum of squared euclidean distance (SSED) and the boundaries of lesions’ projection from beams’ eye view are used as supervised parameters to determine the optimal isocenter numbers. The collimator angle is optimized by minimizing the sum of the MLC opening area from all gantry angles for each arc. In all, 10 clinical cases treated during 2016–2017 were compared to plan quality of GO script generated plans. Paddick gradient index (GI), conformity index (CI), and local brain volume receiving 12 Gy (local V12 Gy) around each lesion were compared.ResultFor four cases, the number of isocenters was reduced in the GO plans. For four other cases, the GO plans had the same number of isocenters as their corresponding clinical plans but with different lesion grouping. The GO plans had significantly lower GI (4.1 ± 1.0 vs 4.4 ± 0.9,P < 0.0001) and local V12 Gy (5.1 ± 4.2 vs 5.5 ± 4.3 in cm3,P < 0.0001), but not significantly different mean normal brain dose or CI. The volume of normal brain receiving ≥6 Gy was significantly lower in the GO plans. The total time to run the GO script for each case was <2 min.ConclusionThe GO software automates lesion grouping, isocenter placement, and the collimator angles for SRS VMAT planning. When tested on 10 cases, the GO script resulted in improved plan quality and shorter planning time when compared to the clinical SRS VMAT plans.
Characterization of Patients With Axial Spondyloarthritis by Enthesitis Presence: Data from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry
Authors: Mease Philip J. , Liu Mei , Rebello Sabrina , Hua Winnie , McLean Robert R. , Yi Esther , Park Yujin , Ogdie Alexis 
Published: July 2020

ObjectiveTo compare the characteristics of patients with axial spondyloarthritis (axSpA) who had enthesitis versus those without enthesitis.MethodsThis study included adult patients with axSpA enrolled in the Corrona Psoriatic Arthritis/Spondyloarthritis Registry (March 2013 to August 2018). Enthesitis was assessed at enrollment via the Spondyloarthritis Research Consortium of Canada Enthesitis Index. Characteristics were compared between patients with and without enthesitis using t tests or Wilcoxon rank‐sum tests for continuous variables and χ2 or Fisher exact tests for categorical variables.ResultsOf 477 patients with axSpA, 121 (25.4%) had enthesitis (mean, 3.9 sites) at enrollment. Higher proportions of patients with enthesitis were female and had nonradiographic axSpA than those without enthesitis (both P < 0.05). Additionally, higher proportions of patients with enthesitis had prior biologic (38.8% vs 27.2%) and conventional synthetic disease‐modifying antirheumatic drug (csDMARD; 24.8% vs 13.3%) use and were currently receiving a combination of biologics and csDMARDs (28.6% vs 18.1%) than those without enthesitis. Patients with enthesitis had worse disease activity (tender and swollen joint counts, physician global assessment, Ankylosing Spondylitis Disease Activity Score, Bath Ankylosing Spondylitis Disease Activity Index, and Bath Ankylosing Spondylitis Functional Index), spinal mobility, and quality of life (pain, fatigue, Health Assessment Questionnaire, and EuroQol visual analog scale scores); greater work impairment; and had a history of depression and fibromyalgia than those without enthesitis (all P < 0.05).ConclusionIn this US‐based real‐world study, enthesitis in patients with axSpA was associated with worse disease activity and quality of life than those with no enthesitis.
Lithium Sulfonate Functionalization of Carbon Cathodes as a Substitute for Lithium Nitrate in the Electrolyte of Lithium–Sulfur Batteries
Authors: Fretz Samuel J. , Pal Urbi , Girard Gaetan M. A. , Howlett Patrick C. , Palmqvist Anders E. C. 
Published: July 2020

AbstractA method for grafting lithium sulfonate (LiSO3) groups to carbon surfaces is developed and the resulting carbons are evaluated for their potential to reduce the lithium polysulfide (LiPS) shuttle in lithium–sulfur (Li–S) batteries, replacing the common electrolyte additive lithium nitrate (LiNO3). The LiSO3 groups are attached to the ordered mesoporous carbon (CMK3) surface via a three‐step procedure to synthesize LiSO3‐CMK3 by bromomethylation, sodium sulfite (Na2SO3) substitution, and cation exchange. As a comparison, ethylenediamine (EN)‐substituted CMK3, EN‐CMK3, is also synthesized and tested. When used as a cathode in Li–S batteries, the unfunctionalized CMK3 suffers from strong LiPS shuttling as evidenced by its low initial Coulombic efficiencies (ICEs, <10%) compared to its functionalized derivatives EN‐CMK3 and LiSO3‐CMK3 (ICEs >75%). Postcycling analysis reveals the benefits of cathode surface functionalization on the lithium anode via an attenuated LiPS shuttle. When monitored at open circuit, the functionalized cathodes maintain their cell voltages much better than the CMK3 control and concurrent electrochemical impedance spectroscopy reveals their higher total cell resistance, which provides evidence for a reduced LiPS shuttle in the vicinity of both electrodes. Overall, such surface groups show promise as cathode‐immobilized “lithium nitrate mimics.”
Ultrasoft Liquid Metal Elastomer Foams with Positive and Negative Piezopermittivity for Tactile Sensing
Authors: Yang Jiayi , Tang David , Ao Jinping , Ghosh Tushar , Neumann Taylor V. , Zhang Dongguang , Piskarev Yegor , Yu Tingting , Truong Vi Khanh , Xie Kai , Lai Ying‐Chih , Li Yang , Dickey Michael D. 
Published: July 2020

AbstractSoft, capacitive tactile (pressure) sensors are important for applications including human–machine interfaces, soft robots, and electronic skins. Such capacitors consist of two electrodes separated by a soft dielectric. Pressing the capacitor brings the electrodes closer together and thereby increases capacitance. Thus, sensitivity to a given force is maximized by using dielectric materials that are soft and have a high dielectric constant, yet such properties are often in conflict with each other. Here, a liquid metal elastomer foam (LMEF) is introduced that is extremely soft (elastic modulus 7.8 kPa), highly compressible (70% strain), and has a high permittivity. Compressing the LMEF displaces the air in the foam structure, increasing the permittivity over a large range (5.6–11.7). This is called “positive piezopermittivity.” Interestingly, it is discovered that the permittivity of such materials decreases (“negative piezopermittivity”) when compressed to large strain due to the geometric deformation of the liquid metal droplets. This mechanism is theoretically confirmed via electromagnetic theory, and finite element simulation. Using these materials, a soft tactile sensor with high sensitivity, high initial capacitance, and large capacitance change is demonstrated. In addition, a tactile sensor powered wirelessly (from 3 m away) with high power conversion efficiency (84%) is demonstrated.
Engineering Biomolecular Self‐Assembly at Solid–Liquid Interfaces
Authors: Zhang Shuai , Chen Jiajun , Liu Jianli , Pyles Harley , Baker David , Chen Chun‐Long , De Yoreo James J. 
Published: July 2020

AbstractBiomolecular self‐assembly is a key process used by life to build functional materials from the “bottom up.” In the last few decades, bioengineering and bionanotechnology have borrowed this strategy to design and synthesize numerous biomolecular and hybrid materials with diverse architectures and properties. However, engineering biomolecular self‐assembly at solid–liquid interfaces into predesigned architectures lags the progress made in bulk solution both in practice and theory. Here, recent achievements in programming self‐assembly of peptides, proteins, and peptoids at solid–liquid interfaces are summarized and corresponding applications are described. Recent advances in the physical understandings of self‐assembly pathways obtained using in situ atomic force microscopy are also discussed. These advances will lead to novel strategies for designing biomaterials organized at and interfaced with inorganic surfaces.
Kirigami‐Inspired Inflatables with Programmable Shapes
Authors: Jin Lishuai , Forte Antonio Elia , Deng Bolei , Rafsanjani Ahmad , Bertoldi Katia 
Published: July 2020

AbstractKirigami, the Japanese art of paper cutting, has recently enabled the design of stretchable mechanical metamaterials that can be easily realized by embedding arrays of periodic cuts into an elastic sheet. Here, kirigami principles are exploited to design inflatables that can mimic target shapes upon pressurization. The system comprises a kirigami sheet embedded into an unstructured elastomeric membrane. First, it is shown that the inflated shape can be controlled by tuning the geometric parameters of the kirigami pattern. Then, by applying a simple optimization algorithm, the best parameters that enable the kirigami inflatables to transform into a family of target shapes at a given pressure are identified. Furthermore, thanks to the tessellated nature of the kirigami, it is shown that we can selectively manipulate the parameters of the single units to allow the reproduction of features at different scales and ultimately enable a more accurate mimicking of the target.
Anomalous Behavior of 2D Janus Excitonic Layers under Extreme Pressures
Authors: Li Han , Qin Ying , Ko Byeongkwan , Trivedi Dipesh B. , Hajra Debarati , Sayyad Mohammed Yasir , Liu Lei , Shim Sang‐Heon , Zhuang Houlong , Tongay Sefaattin 
Published: July 2020

AbstractNewly discovered 2D Janus transition metal dichalcogenides layers have gained much attention from a theory perspective owing to their unique atomic structure and exotic materials properties, but little to no experimental data are available on these materials. Here, experimental and theoretical studies establish the vibrational and optical behavior of 2D Janus S–W–Se and S–Mo–Se monolayers under high pressures for the first time. Chemical vapor deposition (CVD)‐grown classical transition metal dichalcogenides (TMD) monolayers are first transferred onto van der Waals (vdW) mica substrates and converted to 2D Janus sheets by surface plasma technique, and then integrated into a 500 µm size diamond anvil cell for high‐pressure studies. The results show that 2D Janus layers do not undergo phase transition up to 15 GPa, and in this pressure regime, their vibrational modes exhibit a nonmonotonic response to the applied pressures (dω/dP). Interestingly, these 2D Janus monolayers exhibit unique blueshift in photoluminescence (PL) upon compression, which is in contrast to many other traditional semiconductor materials. Overall theoretical simulations offer in‐depth insights and reveal that the overall optical response is a result of competition between the ab‐plane (blueshift) and c‐axis (redshift) compression. The overall findings shed the very first light on how 2D Janus monolayers respond under extreme pressures and expand the fundamental understanding of these materials.
High‐Nickel NMA: A Cobalt‐Free Alternative to NMC and NCA Cathodes for Lithium‐Ion Batteries
Authors: Li Wangda , Lee Steven , Manthiram Arumugam 
Published: July 2020

AbstractHigh‐nickel LiNi1−x−yMnxCoyO2 (NMC) and LiNi1−x−yCoxAlyO2 (NCA) are the cathode materials of choice for next‐generation high‐energy lithium‐ion batteries. Both NMC and NCA contain cobalt, an expensive and scarce metal generally believed to be essential for their electrochemical performance. Herein, a high‐Ni LiNi1−x−yMnxAlyO2 (NMA) cathode of desirable electrochemical properties is demonstrated benchmarked against NMC, NCA, and Al–Mg‐codoped NMC (NMCAM) of identical Ni content (89 mol%) synthesized in‐house. Despite a slightly lower specific capacity, high‐Ni NMA operates at a higher voltage by ≈40 mV and shows no compromise in rate capability relative to NMC and NCA. In pouch cells paired with graphite, high‐Ni NMA outperforms both NMC and NCA and only slightly trails NMCAM and a commercial cathode after 1000 deep cycles. Further, the superior thermal stability of NMA to NMC, NCA, and NMCAM is shown using differential scanning calorimetry. Considering the flexibility in compositional tuning and immediate synthesis scalability of high‐Ni NMA very similar to NCA and NMC, this study opens a new space for cathode material development for next‐generation high‐energy, cobalt‐free Li‐ion batteries.
Deep‐Learning‐Enabled MXene‐Based Artificial Throat: Toward Sound Detection and Speech Recognition
Authors: Jin Yukun , Wen Bo , Gu Zixiong , Jiang Xiantao , Shu Xiaolan , Zeng Zhenping , Zhang Yupeng , Guo Zhinan , Chen Yun , Zheng Tingting , Yue Yutao , Zhang Han , Ding Huijun 
Published: July 2020

AbstractWearable sound detectors require strain sensors that are stretchable, sensitive, and capable of adhering conformably to the skin, and toward this end, 2D materials hold great promise. However, the vibration of vocal cords and muscle contraction are complex and changeable, which can compromise the sensing performance of devices. By combining deep learning and 2D MXenes, an MXene‐based sound detector is prepared successfully with improved recognition and sensitive response to pressure and vibration, which facilitate the production of a high‐recognition and resolution sound detector. By training and testing the deep learning network model with large amounts of data obtained by the MXene‐based sound detector, the long vowels and short vowels of human pronunciation are successfully recognized. The proposed scheme accelerates the application of artificial throat devices in biomedical fields and opens up practical applications in voice control, motion monitoring, and many other fields.
The Layered Oxides in Lithium and Sodium‐Ion Batteries: A Solid‐State Chemistry Approach
Authors: Delmas Claude , Carlier Dany , Guignard Marie 
Published: July 2020

AbstractThis paper gives an overview of the research carried out on lithium and sodium layered materials as positive electrodes of lithium (sodium)‐ion batteries. It focuses on the solid‐state chemistry contribution to discover new materials and to optimize the properties versus the requirements imposed by the applications. Among, all material structures, which are considered, the layered ones (lithium based), are the best candidates for high energy density batteries for mobile applications. Recently, the homologous Na materials, which have lower energy, are considered for stationary applications due to their low price. Starting for LiMO2 materials or NaxMO2 (0.5 < x < 1), many substituted phases, obtained by high‐temperature solid‐state chemistry, have allowed stabilizing the layered structure in large composition domains to increase the specific capacity, which is directly related to the number of exchanged electrons during the cycling process.
Understanding the Reactivity of a Thin Li1.5Al0.5Ge1.5(PO4)3 Solid‐State Electrolyte toward Metallic Lithium Anode
Authors: Paolella Andrea , Zhu Wen , Xu Gui‐Liang , La Monaca Andrea , Savoie Sylvio , Girard Gabriel , Vijh Ashok , Demers Hendrix , Perea Alexis , Delaporte Nicolas , Guerfi Abdelbast , Liu Xiang , Ren Yang , Sun Cheng‐Jun , Lu Jun , Amine Khalil , Zaghib Karim 
Published: July 2020

AbstractThe thickness of solid‐state electrolytes (SSEs) significantly affects the energy density and safety performance of all‐solid‐state lithium batteries. However, a sufficient understanding of the reactivity toward lithium metal of ultrathin SSEs (<100 µm) based on NASICON remains lacking. Herein, for the first time, a self‐standing and ultrathin (70 µm) NASICON‐type Li1.5Al0.5Ge1.5(PO4)3 (LAGP) electrolyte via a scalable solution process is developed, and X‐ray photoelectron spectroscopy reveals that changes in LAGP at the metastable Li–LAGP interface during battery operation is temperature dependent. Severe germanium reduction and decrease in LAGP particle size are detected at the Li–LAGP interface at elevated temperature. Oriented plating of lithium metal on its preferred (110) face occurs during in situ X‐ray diffraction cycling.
An Indian child with Coats plus syndrome due to mutations in STN1
Authors: Passi Gouri Rao , Shamim Uzma , Rathore Surabhi , Joshi Aditi , Mathur Aradhana , Parveen Shaista , Sharma Pooja , Crow Yanick J. , Faruq Mohammed 
Published: July 2020

AbstractThe role of the CTC1–STN1–TEN1 (CST) complex in Coats plus syndrome (CP), as well as other telomeropathy‐phenotypes and disorders of genome instability is well documented. We report an Indian child with a clinical diagnosis of CP who presented to us with retinal exudates, extensive cerebral calcification, developmental delay and severe anemia consequent upon chronic gastrointestinal (GI) bleeding. Whole exome sequencing revealed compound heterozygous variants in STN1 as the probable genetic cause leading to CP in the present case. Of the two variants, the nonsense variant c.397C>T (p.Arg133*) was a truncating variant leading to loss of full protein length whereas the second variant c.985G>C (p.Ala329Pro) was novel and neither reported in ExAC, 1KGP or gnomAD. The deleteriousness of the novel variant was explored through molecular dynamics simulation analysis where p.Ala329Pro mutation affected C‐terminal domain interaction between STN1 and TEN1 complex. Hormonal therapy using ethinyl estradiol and norethisterone was apparently associated with a clinically useful, although poorly sustained, decrease in blood transfusion requirement in the proband.
Stereoselektive Synthese von Tropanen über eine 6π‐elektrocyclische Ringöffnung/ Huisgen‐[3+2]‐Cycloadditionskaskade von monocyclopropanierten Heterocyclen
Authors: Sonnleitner Carina M. , Park Saerom , Eckl Robert , Ertl Thomas , Reiser Oliver 
Published: July 2020

AbstractDie Synthese von Tropanen über eine mikrowellenunterstützte, stereoselektive 6π‐elektrocyclische Ringöffnung/ Huisgen‐[3+2]‐Cycloadditionskaskade von cyclopropanierten Pyrrol‐ und Furanderivaten mit elektronenarmen Dipolarophilen wird demonstriert. Ausgehend von Furanen oder Pyrrolen sind 8‐Aza‐ und 8‐Oxabicyclo[3.2.1]octane in zwei Schritten sowohl dia‐ als auch enantioselektiv zugänglich und stellen vielseitige Bausteine für die Synthese pharmazeutisch relevanter Zielmoleküle, insbesondere neuer Kokain‐Analoga mit verschiedenen Substituenten an den C‐6/C‐7‐Positionen des Tropanringsystems, dar. Darüber hinaus ist das 2‐Azabicyclo[2.2.2]octan‐Grundgerüst (Isochinuclidin), das in vielen natürlichen und pharmazeutischen Produkten vertreten ist, über diese Synthesestrategie zugänglich.