bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impaired cerebral autoregulation is associated with poststroke cognitive impairment
Authors: Chi Nai‐Fang , Hu Han‐Hwa , Chan Lung , Wang Cheng‐Yen , Chao Shu‐Ping , Huang Li‐Kai , Ku Hsiao‐Lun , Hu Chaur‐Jong 
Published: May 2020

AbstractObjectiveTo investigate whether dynamic cerebral autoregulation (CA) and neuroimaging characteristics are determinants of poststroke cognitive impairment (PSCI).MethodsEighty patients within 7 days of acute ischemic stroke and 35 age‐ and sex‐matched controls were enrolled. In the patients with stroke, brain magnetic resonance imaging and dynamic CA were obtained at baseline, and dynamic CA was followed up at 3 months and 1 year. Montreal Cognitive Assessment (MoCA) was performed at 3 months and 1 year. Patients with a MoCA score <23 at 1 year were defined as having PSCI, and those with a MoCA score that decreased by 2 points or more between the 3‐month and 1‐year assessments were defined as having progressive cognitive decline.ResultsIn total, 65 patients completed the study and 16 developed PSCI. The patients with PSCI exhibited poorer results for all cognitive domains than did those without PSCI. The patients with PSCI also had poorer CA (lower phase shift between cerebral blood flow and blood pressure waveforms in the very low frequency band) compared with that of the patients without PSCI and controls at baseline and 1 year. CA was not different between the patients without PSCI and controls. In the multivariate analysis, low education level, lobar microbleeds, and impaired CA (very low frequency phase shift [≤46°] within 7 days of stroke), were independently associated with PSCI. In addition, impaired CA was associated with progressive cognitive decline.InterpretationLow education level, lobar microbleeds, and impaired CA are involved in the pathogenesis of PSCI.
A Lithium Metal Anode Surviving Battery Cycling Above 200 °C
Authors: Fu Lin , Wan Mintao , Zhang Bao , Yuan Yifei , Jin Yang , Wang Wenyu , Wang Xiancheng , Li Yuanjian , Wang Li , Jiang Jianjun , Lu Jun , Sun Yongming 
Published: May 2020

AbstractLithium (Li) metal electrode cannot endure elevated temperature (e.g., >200 °C) with the regular battery configuration due to its low melting point (180.5 °C) and high reactivity, which restricts its application in high‐temperature Li metal batteries for energy storage and causes safety concerns for regular ambient‐temperature Li metal batteries. Herein, this work reports a Li5B4/Li composite featuring a 3D Li5B4 fibrillar framework filled with metallic Li, which maintains its initial structure at 325 °C in Ar atmosphere without leakage of the liquid Li. The capillary force caused by the porous structure of the Li4B5 fibrillar framework, together with its lithiophilic surface, restricts the leakage of liquid metallic Li and enables good thermal tolerance of the Li5B4/Li composite. Thus, it can be facilely operated for rechargeable high‐temperature Li metal batteries. Li5B4/Li electrodes are coupled with a garnet‐type ceramic electrolyte (Li6.5La3Zr0.5Ta1.5O12) to fabricate symmetric cells, which exhibit stable Li stripping/plating behaviors with low overpotential of ≈6 mV at 200 °C using a regular sandwich‐type cell configuration. This work affords new insights into realizing a stable Li metal anode for high‐temperature Li metal batteries with a simple battery configuration and high safety, which is different from traditional molten‐salt Li metal batteries using a pristine metallic Li anode.
Preparation and characterization of a class of self‐doping aromatic polyoxadiazole electrochromic materials
Authors: Yu Yuanyuan , Zhu Jiadeng , Gao Huihui , Yang Chen , Chen Sheng , Zhang Sihang , Jiang Mengjin 
Published: May 2020

AbstractThis article describes the preparation and characterization of six novel organic‐soluble aromatic polyoxadiazole sulfonates (PODs) containing different side groups through sulfation polycondensation, which can undergo reversible redox reactions and self‐doping. In order to further characterize its properties, they are assembled into solution type electrochromic devices (ECDs), which turn orange‐yellow, purple, pink, deep pink, blue‐ray green, and reddish‐purple, respectively, by applying a voltage. The assembled ECDs show extremely high color contrast, which has a range from 34 to 97.6% at the maximum absorption wavelength in coloring state. These POD materials are n‐doped type, so they have the potential to work with other p‐doped electrochromic polymers to produce colorful devices.
RETRACTED: Penfluridol triggers mitochondrial‐mediated apoptosis and suppresses glycolysis in colorectal cancer cells through down‐regulating hexokinase‐2
Authors: Wang Ning‐Ning , Zhang Peng‐Zhen , Zhang Jing , Wang Hai‐Ning , Li Ling , Ren Feng , Dai Peng‐Fei , Li Hui , Lv Xiao‐Feng 
Published: May 2020

AbstractPenfluridol, a commonly used antipsychotic agent in a clinical setting, exhibits potential anticancer properties against various human malignancies. Here, we investigated the effect of penfluridol on the biological behavior of colorectal cancer (CRC) cells. Cell viability and clonogenic potential were detected by the cell counting kit‐8 and colony formation assay. The cell apoptosis and cell cycle distribution were quantified through flow cytometry. Caspase‐3 activity, glucose consumption, lactate production, and intracellular ATP levels were evaluated using the corresponding commercial detection kits. The protein levels of related genes were detected through western blotting. Mitochondrial membrane potential was detected using JC‐1 staining. A CRC xenograft tumor model was used to validate the antitumor activity of penfluridol in vivo. Penfluridol reduced cell survival and promoted apoptotic cell death effectively through the mitochondria‐mediated intrinsic pathway in a dose‐dependent manner. Furthermore, the process of glycolysis in HCT‐116 and HT‐29 cells was inhibited upon penfluridol treatment, as evidenced by the decrease in glucose consumption, lactate production, and intracellular ATP levels. Further mechanistic studies revealed that penfluridol influenced cell apoptosis and glycolysis in CRC cells by downregulating hexokinase‐2 (HK‐2). The proapoptotic effect and glycolytic inhibition‐induced by penfluridol were effectively reversed by HK‐2 overexpression. Consistent with in vitro results, penfluridol could also suppress tumor growth and trigger apoptosis in vivo. Penfluridol triggers mitochondrial‐mediated apoptosis and induces glycolysis inhibition via modulating HK‐2 in CRC and provides a theoretical basis to support penfluridol as a repurposed drug for CRC patients.
An instrument for the evaluation of muscle dysmorphia: The Italian validation of the adonis complex questionnaire
Authors: Riccobono Giulia , Pompili Assunta , Iorio Carla , Carducci Giorgio , Parnanzone Serena , Pizziconi Giulia , Iannitelli Angela , Pacitti Francesca 
Published: May 2020

AbstractBackground and aimsMuscle dysmorphia (MDM), or bigorexia, is a subcategory of body dysmorphic disorder (BDD), also known as “Adonis Complex” in nonscientific contexts. One of the most used tools to investigate MDM is the Adonis Complex Questionnaire (ACQ). The ACQ is a 13‐item US questionnaire, designed for male subjects only, related to the dissatisfaction and concerns about physical appearance. The aim of the current study was to evaluate the validity of the Italian version of the ACQ.MethodsThe instrument was administered to a sample of 322 male adults, recruited from the general population. We used the maximum‐likelihood confirmatory factorial analysis (CFA), analyzing the covariance matrices with AMOS 24.0, to evaluate the different factorial models proposed in the literature.ResultsThe evaluation of the factorial structure of the Italian version of the ACQ demonstrates the greater stability and internal consistency of the two‐factor model, compared to the original three‐factor model. The factors have no correlation with the demographic characteristics of the sample.ConclusionsThe present study confirms the validity and the reliability of the Italian two‐factor version of the ACQ and highlights the general tendency, among Italian males, to have concerns about their own physical appearance with recurring thoughts and eating behaviors finalized to improve it. Our study represents an advance in the use of adequate and reliable instruments to assess concerns about physical appearance in the Italian male population.
Circular economy in Latin America: A systematic literature review
Authors: Betancourt Morales Claudia Marcela , Zartha Sossa Jhon Wilder 
Published: May 2020

AbstractThe purpose of this study is to identify circular economy concept trends of Latin America with regards to Europe, in which a systematic review of literature (SRL) was made using Scopus data in order to define the search, to select the relevant articles, and to analyze the results. Seventy‐one articles from Scopus were reviewed, and the analysis was complemented by the analysis with 57 documents from other scientific Web browsers such as Mendeley, Scopus, Academic Google, ScienceDirect, and SciELo which sum a total of 128 documents which the majority have come from Europe. Main concepts were identified, barriers and trends. The main conclusion was which the current concept is not very clear; in spite of Europe knows that limitation, Latin America is making the same mistake implementation.
Risk factors and predictors of lymph nodes metastasis and distant metastasis in newly diagnosed T1 colorectal cancer
Authors: Guo Kaibo , Feng Yuqian , Yuan Li , Wasan Harpreet S. , Sun Leitao , Shen Minhe , Ruan Shanming 
Published: May 2020

AbstractBackgroundLymph nodes metastasis (LNM) and distant metastasis (DM) are important prognostic factors in colorectal cancer (CRC) and determine the following treatment approaches. We aimed to find clinicopathological factors associated with LNM and DM, and analyze the prognosis of CRC patients with T1 stage.MethodsA total of 17 516 eligible patients with T1 CRC were retrospectively enrolled in the study based on the Surveillance, Epidemiology, and End Results (SEER) database during 2004‐2016. Logistic regression analysis was performed to identify risk factors for LNM and DM. Unadjusted and adjusted Cox proportional hazard models were used to identify prognostic factors for overall survival. We performed the cumulative incidence function (CIF) to further determine the prognostic role of LNM and DM in colorectal cancer‐specific death (CCSD). LNM, DM, and OS nomogram were constructed based on these models and evaluated by the C‐index and calibration plots for discrimination and accuracy, respectively. The clinical utility of the nomograms was measured by decision curve analyses (DCAs) and subgroups with different risk scores.ResultsTumor grade, mucinous adenocarcinoma, and age accounted for the first three largest proportion among the LNM nomogram scores (all, P < .001), whereas N stage, carcinoembryonic antigen (CEA), and tumor size occupied the largest percentage in DM nomogram (all, P < .001). OS nomogram was formulated to visually to predict 3‐, 5‐, and 10‐ year overall survivals for patients with T1 CRC. The calibration curves showed an effectively predictive accuracy of prediction nomograms, of which the C‐index were 0.666, 0.874, and 0.760 for good discrimination, respectively. DCAs and risk subgroups revealed the clinical effectiveness of these nomograms.ConclusionsNovel population‐based nomograms for T1 CRC patients could objectively and accurately predict the risk of LNM and DM, as well as OS for different stages. These predictive tools may help clinicians to make individual clinical decisions, before clinical management.
Assessing the predictive validity of perceived globalness and country of origin of foreign brands in quality judgments among consumers in emerging markets
Authors: Han C. Min 
Published: May 2020

AbstractConsumers in emerging markets are known to have strong preferences for well‐known foreign brands. Drawing on schema and categorization theories, this study empirically investigates how accessible two components of brand foreignness – globalness and country of brand origin – are in consumer perceptions of brand quality in emerging markets. In addition, we argue that brand globalness can be shaped by inferential reasoning and test how consumer perceptions of brand globalness are affected by both a brand's country of origin and its perceived quality. Two different studies were conducted with young‐adult consumers in China. The study found that in their evaluations of foreign brands consumers are more influenced by country of origin than by brand globalness. It also found that consumers tend to perceive a high level of globalness in high‐quality brands and brands from a favorable country‐of‐origin. Further, this tendency was found to differ between well‐known and lesser‐known brands. These findings confirm the predictive validity of country of origin, but contrast with extant literature on the role of brand globalness as a principal quality cue for foreign brands among consumers in emerging markets. Our findings also imply brand globalness can be an inferred attribute of perceived brand quality and country‐of‐origin image. Keywords: brand foreignness, brand globalness, country‐of‐origin effect, emerging markets.
Management of a patient presenting with anterior STEMI with concomitant COVID‐19 infection early in the course of the U.S. pandemic
Authors: Rothstein Eric S. , Welch Terrence D. , Andrus Bruce W. , Jayne John E. 
Published: May 2020

AbstractThe coronavirus disease‐2019 (COVID‐19) is a viral illness with heterogenous clinical manifestations, ranging from mild symptoms to severe acute respiratory distress syndrome and shock caused by the severe acute respiratory syndrome coronavirus‐2. The global healthcare community is rapidly learning more about the effects of COVID‐19 on the cardiovascular system, as well as the strategies for management of infected patients with cardiovascular disease. There is minimal literature available surrounding the relationship between COVID‐19 infection and acute coronary syndrome. We describe the case of a woman who presented with an acute anterior ST‐elevation myocardial infarction managed by primary percutaneous coronary intervention, who subsequently developed severe COVID‐19 infection and ultimately succumbed to multisystem organ failure.
Metabolic syndrome and concomitant diabetes mellitus are associated with higher risk of cardiovascular comorbidity in patients with primary glomerular diseases: A retrospective observational study
Authors: Xie Zhiyong , Li Zhilian , Dong Wei , Chen Yuanhan , Li Ruizhao , Wu Yanhua , Lin Ting , Tao Yiming , Liang Huaban , Wang Wenjian , Liu Shuangxin , Ye Zhiming , Shi Wei , Liang Xinling 
Published: May 2020

AbstractBackgroundMetabolic syndrome (MS) and diabetes mellitus (DM) are risk factors for cardiovascular diseases in general population. However, there was a paucity of studies investigating their impact in primary glomerular diseases (PGD).HypothesisMS and concomitant DM are associated with higher risk of cardiovascular comorbidity in PGD.MethodsIn a retrospective observational design, we analyzed 3622 hospitalized adult PGD patients and compared the prevalence of cardiovascular comorbidity in non‐MS, MS with and without DM. Risk factors for cardiovascular comorbidity were identified using univariate and multivariate logistic regression.ResultsAmong 3622 PGD patients, 308 (8.5%) cases accompanied with MS, including 180 (5.0%) patients with DM and 128 (3.5%) without DM. One hundred and sixty four (4.5%) cases coexisted with cardiovascular comorbidity. Patients with MS and concomitant DM exhibited a higher prevalence of cardiovascular comorbidity than those without MS stratified by estimated glomerular filtration rate and pathological types. Logistic regression showed that MS and concomitant DM (OR: 2.496, 95% CI: 1.600‐3.894, P < .001), older age (OR: 1.060, 95% CI: 1.047‐1.074, P < .001), male (OR: 1.536, 95% CI: 1.072‐2.200, P = .019), higher level of serum ti (OR: 1.002, 95% CI: 1.001‐1.003, P < .001), hyperuricemia (OR: 1.901, 95% CI: 1.327‐2.725, P < .001), idiopathic membranous nephropathy (OR: 2.874, 95% CI: 1.244‐6.640, P < .001) and focal segmental glomerulosclerosis (OR: 2.906, 95% CI: 1.147‐7.358, P < .001) were independently associated with a higher risk for cardiovascular comorbidity.ConclusionsIn PGD patients, MS and concomitant DM are associated with an increased risk for cardiovascular comorbidity. More evidence for the causal link between MS/DM and cardiovascular outcomes is needed to be clarified.
Kikuyugrass germplasm collections in the United States and Australia show low levels of genetic diversity as revealed by DArTseq genotyping
Authors: Pudzianowska Marta , Mock Tyler J. , Martin Peter M. , Lukaszewski Adam J. , Baird James H. 
Published: May 2020

AbstractKikuyugrass [Cenchrus clandestinus (Hochst. ex Chiov.) Morrone (= Pennisetum clandestinum Hochst. ex Chiov.)] is a warm‐season grass native to Africa. It was introduced into the United States as forage in Hawaii and for erosion control in California. Kikuyugrass is considered invasive and currently is on the USDA's noxious weed list. Since complete eradication is difficult, it has become the primary species on several golf courses, athletic fields, and lawns. Kikuyugrass possesses exceptional quality with considerable cultural inputs, and little or no winter dormancy compared with other warm‐season turfgrasses. With breeding efforts directed specifically at reducing aggressiveness and improving texture, thus reducing inputs, it could become a valuable turf‐type species in coastal and inland California. The genetic diversity of kikuyugrass was investigated using single nucleotide polymorphism (SNP) and silicoDArT (presence or absence) markers revealed by the Diversity Arrays Technology sequencing (DArTseq) platform. Accessions were sampled throughout California, Hawaii, and Australia, both from natural stands and various collections. Among the 254 accessions tested, two distinct groups were discovered, and there was no geographic pattern to this differentiation. The overall level of SNP polymorphism was low (polymorphic information content [PIC] average = .33, PIC median = .38). Most (76%) of the observed genetic variation was within populations, whereas 24% was among populations. Average genetic distances within populations ranged from 0.09 to 0.16, whereas distances among populations ranged from 0.13 to 0.36. Accessions from Hawaii and Australia were the most diverse; however, a detectable level of genetic diversity of kikuyugrass also exists in California, mostly because of the past introductions from Australia.
How to alleviate consumer skepticism concerning corporate responsibility: The role of content and delivery in CSR communications
Authors: Moreno Floritzel , Kang Jiyun 
Published: May 2020

AbstractDue to heightened levels of consumer skepticism, it has become crucial for many companies to discern what corporate social responsibility (CSR) activities to undertake and how to deliver CSR‐related information to consumers. We aim to examine the role of consumer evaluations of a company's CSR, from both content and delivery perspectives, in shaping consumer skepticism about overall corporate responsibility and advancing retail patronage intentions. We conducted an online nationwide survey with 402 U.S. consumers and used structural equation modeling for the data analysis. The results indicate that the fit between a company's core values and the CSR activities it communicates plays a significant role in alleviating skepticism, while the fit between a consumer's personal values and CSR activity does not have significant effects on skepticism. Both inauthentic information and self‐promotional tone significantly increase skepticism, and skepticism is found to be a significant mediator in the paths from CSR content and delivery factors to retail patronage intentions. Our supplementary analyses suggest that delivery of CSR information can be more important than the content itself in affecting skepticism. The results should inspire practitioners, when planning for CSR communication, to carefully consider fit, tone, and authenticity in order to minimize skepticism and avoid negatively impacting consumers' retail patronage intentions.
Ignoring non‐English‐language studies may bias ecological meta‐analyses
Authors: Konno Ko , Akasaka Munemitsu , Koshida Chieko , Katayama Naoki , Osada Noriyuki , Spake Rebecca , Amano Tatsuya 
Published: May 2020

AbstractMeta‐analysis plays a crucial role in syntheses of quantitative evidence in ecology and biodiversity conservation. The reliability of estimates in meta‐analyses strongly depends on unbiased sampling of primary studies. Although earlier studies have explored potential biases in ecological meta‐analyses, biases in reported statistical results and associated study characteristics published in different languages have never been tested in environmental sciences. We address this knowledge gap by systematically searching published meta‐analyses and comparing effect‐size estimates between English‐ and Japanese‐language studies included in existing meta‐analyses. Of the 40 published ecological meta‐analysis articles authored by those affiliated to Japanese institutions, we find that three meta‐analysis articles searched for studies in the two languages and involved sufficient numbers of English‐ and Japanese‐language studies, resulting in four eligible meta‐analyses (i.e., four meta‐analyses conducted in the three meta‐analysis articles). In two of the four, effect sizes differ significantly between the English‐ and Japanese‐language studies included in the meta‐analyses, causing considerable changes in overall mean effect sizes and even their direction when Japanese‐language studies are excluded. The observed differences in effect sizes are likely attributable to systematic differences in reported statistical results and associated study characteristics, particularly taxa and ecosystems, between English‐ and Japanese‐language studies. Despite being based on a small sample size, our findings suggest that ignoring non‐English‐language studies may bias outcomes of ecological meta‐analyses, due to systematic differences in study characteristics and effect‐size estimates between English‐ and non‐English languages. We provide a list of actions that meta‐analysts could take in the future to reduce the risk of language bias.
Improving the surface roughness in stereolithography by controlling surface angle, hatch spaces, and postcuring time
Authors: Khodaii Javad , Rahimi Abdolreza 
Published: May 2020

AbstractStereolithography is considered as a well‐known rapid prototyping technique that is widely used for injection molding and vacuum casting manufacturing regarding its higher dimensional accuracy and part strength. However, the extensive application of this process has been restricted due to the higher surface roughness and appearance of stair‐step phenomenon. In this article, the influences of process parameters and part orientation on the surface finish are investigated. For this purpose, parts are fabricated with different surface angle, hatch space, and postcuring time. The surface roughness of the parts are measured by contact and noncontact methods. In noncontact method, a digital microscope is used for obtaining the surface profile, and then surface roughness is calculated using MATLAB software. The results showed that the surface roughness was affected by the hatch space, whereas postcuring time had insignificant and negligible effect on the surface roughness. By increasing the surface angle, a sharp increase of surface roughness in up‐facing plane was observed, which was followed by a drop. Finally, with the help of analysis of variance, a mathematical model has been developed considering the process parameters and the responses. Moreover, maximum average estimation error of 14% was obtained between the experimental results of surface roughness values and the estimated
ones.