bluuebunny/crossref_metadata_2025_split huggingface dataset:
Giving voice to those directly affected by the COVID-19 pandemic – the experience and reflections of a person with dementia
Authors: Rochford-Brennan Helen , Keogh Fiona 
Published: November 2020

The coronavirus disease 2019 (COVID-19) pandemic presents unprecedented challenges to society. Behind the daily tally of deaths and cases of infection are individuals and families who are experiencing the ultimate consequence of this disease. Every aspect of our lives has been affected and these affects are amplified for those who have to cocoon and have conditions such as dementia. There is little opportunity to directly hear the experience of those ‘vulnerable adults’ who have been self-isolating for many weeks now. This letter takes the form of a reflective conversation with a person living with dementia. Honouring the principles of public and patient involvement (PPI), it is an attempt to give voice to the experience of one of the many thousands of vulnerable people during the COVID-19 pandemic. As well as describing the effect on her daily life, Helen describes what supports would help at this time. While the focus of attention at the moment is rightly on dealing with the effects of the virus in nursing homes, the many thousands of people living with dementia in the community should not be forgotten.
HR Policy: a Conceptual Approach from the Point of View of Ensuring Economic Security of Business
Authors: Tokmakova E. , Karimova D. , Bryksina P. 
Published: November 2020

In modern conditions of instability of the economic situation, any business should strive to ensure its economic security, the dominant component of which is personnel security. The article is devoted to the definition of the value and role of personnel policy in ensuring the personnel security of the enterprise.
The research methodology is based on a conceptual understanding of the personnel policy as a tool for ensuring personnel security through a set of internal regulations that define the interaction of the employer and employees, allowing, among other tasks, to solve the most important task of preventing threats to the economic security of business from the staff. Based on the study of the personnel policy of a successful Russian company, JSC "Transneft Siberia", it is concluded that it can be defined as a tool for ensuring personnel security, while indicators with sum values that can be used as indicators of personnel security are identified.
The result of the study is a convincing argument for defining personnel policy as a tool for ensuring personnel security, a description of the personnel policy of Transneft Siberia as a set of internal regulations and an indication of the threshold values of personnel security indicators established by this company with a critical assessment. The analyzed experience of a successful Russian company can be used by other organizations in developing their own personnel policy and assessing its level.
Pulp chamber temperature variation evaluation using fiber Bragg grating sensor
Authors: Pant Shweta , Umesh Sharath , Asokan Sundarrajan 
Published: November 2020

The present in vitro study proposes a novel (to the best of our knowledge) methodology employing a fiber Bragg grating sensor for the evaluation of pulp chamber temperature increase during the polymerization of the composite resin induced by the light-curing process. A fiber Bragg grating temperature sensor (FBGTS) has been developed in view of its ease of insertion into the pulp chamber with minimal widening of the pulpal canal. The temperature increase in the pulpal chamber during the polymerization of the composite resin by light curing has been characterized with varying depths of cavities of 1 mm, 1.5 mm, and 2 mm employing FBGTS. Also, the increase in temperature of the pulpal chamber during the polymerization of the composite resin has been studied with variants of the light-curing device. The obtained results are expected to be an indicator towards the potential hazard caused by heat induced pulpal injuries during the polymerization of composite resins using a light-curing device.
Experiences of cervical cancer survivors in Chitwan, Nepal: A qualitative study
Authors: Shrestha Gambhir , Mulmi Rashmi , Phuyal Prabin , Thakur Rahul Kumar , Siwakoti Bhola 
Published: November 2020

Introduction
Cervical cancer is a global leading cause of morbidity and mortality. The majority of cervical cancer deaths occur in developing countries including Nepal. Though knowledge of cervical cancer is an important determinant of women’s participation in prevention and screening for cervical cancer, little is known about this topic in Nepal. This study explores the experiences of cervical cancer survivors and assesses the attitude of family and community towards it and stigma related to this disease in Bharatpur, Nepal.

Methods
The study design was qualitative methods involving two focus-group discussions. A total of 17 cervical cancer survivors, who have completed two years of cancer treatment were selected purposively from Chitwan. All qualitative data were transcribed and translated into English and were thematically analyzed.

Results
The majority of the participants had scant knowledge about cervical cancer, its causative agent, showed less cervical cancer screening, delayed healthcare-seeking behavior despite having persistent symptoms before the diagnosis. The main reasons identified for not uptaking the cervical screening methods were an embarrassment and having no symptoms at all. Most of them endured social stigma related to cervical cancer in the form of physical isolation and verbal abuse.

Conclusions
There is an urgent need for interventions to make women and the public aware of cervical cancer and launch effective health education campaigns, policies for cervical cancer prevention programs. This implementation can save the lives of hundreds of women and help them avoid going through all the negative experiences related to cervical cancer. More studies are required to gain the perspectives, knowledge, experiences, and attitudes of cervical cancer survivors to add to the research.
Emotional distress and adjustment in patients with end-stage kidney disease: A qualitative exploration of patient experience in four hospital trusts in the West Midlands, UK
Authors: Sein Kim , Damery Sarah , Baharani Jyoti , Nicholas Johann , Combes Gill 
Published: November 2020

ObjectivesTo explore patient perceptions and experiences of mild-to-moderate emotional distress and the support offered by kidney units to patients with end-stage kidney disease.MethodsIn-depth, semi-structured qualitative interviews with patients (n = 46) being treated for end-stage kidney disease in four hospital Trusts, with data analysed thematically.ResultsPatients described multiple sources of distress and talked about the substantial burden that emotional challenges raised for their ability to manage their condition and develop coping strategies. Many patients did not feel it appropriate to disclose their emotional issues to staff on the kidney unit, due to a perceived lack of time for staff to deal with such issues, or a perception that staff lacked the necessary skills to provide resolution. Five themes were identified from the patient interviews, broadly related to patients’ experience of distress, and the support offered by the kidney unit: i) the emotional burden that distress placed on patients; ii) patients’ relationship with the treatment for their condition; iii) strategies for coping and adjustment; iv) patient-staff interactions and the support offered by the kidney unit, and v) the mediating impact of the treatment environment on patient experience of distress and their ability to raise emotional issues with staff.ConclusionsMany patients felt unprepared for the likelihood of experiencing emotional issues as part of their condition, for which pre-dialysis education could help in managing expectations, along with support to help patients to develop appropriate coping strategies and adjustments. These findings demonstrate the importance of recognising patient distress and ensuring that talking about distress becomes normalised for patients with end-stage kidney disease.
Peripheral blood levels of brain-derived neurotrophic factor in patients with post-traumatic stress disorder (PTSD): A systematic review and meta-analysis
Authors: Mojtabavi Helia , Saghazadeh Amene , van den Heuvel Leigh , Bucker Joana , Rezaei Nima 
Published: November 2020

Background
Brain-derived neurotrophic factor (BDNF) plays a crucial role in the survival, differentiation, growth, and plasticity of the central nervous system (CNS). Post-traumatic stress disorder (PTSD) is a complex syndrome that affects CNS function. Evidence indicates that changes in peripheral levels of BDNF may interfere with stress. However, the results are mixed. This study investigates whether blood levels of BDNF in patients with post-traumatic stress disorder (PTSD) are different.

Methods
We conducted a systematic search in the major electronic medical databases from inception through September 2019 and identified Observational studies that measured serum levels of BDNF in patients with PTSD compared to controls without PTSD.

Results
20 studies were eligible to be included in the present meta-analysis. Subjects with PTSD (n = 909) showed lower BDNF levels compared to Non-PTSD controls (n = 1679) (SMD = 0.52; 95% confidence interval: 0.18 to 0.85). Subgroup meta-analyses confirmed higher levels of BDNF in patients with PTSD compared to non-PTSD controls in plasma, not serum, and in studies that used sandwich ELISA, not ELISA, for BDNF measurement. Meta-regressions showed no significant effect of age, gender, NOS, and sample size.

Conclusions
PTSD patients had increased serum BDNF levels compared to healthy controls. Our finding of higher BDNF levels in patients with PTSD supports the notion that PTSD is a neuroplastic disorder.
Trastornos del movimiento, neuroimagen funcional y déficits neuropsicológicos asociados a la abstinencia prolongada a la cocaína: a propósito de un caso.
Authors:   Hospital Vega Baja, Orihuela, Madrid García Domingo , Martínez-Lozano Marta García ,   Hospital Vega Baja, Orihuela, Fernández Álvaro Xenia ,   Hospital Vega Baja, Orihuela, García Pla Sandro ,   Hospital Vega Baja, Orihuela, Gómez Regalado Sara ,   Hospital Vega Baja, Orihuela, Moreno González José Alberto ,   Hospital Vega Baja, Orihuela, Caballero Sánchez Maria del Mar ,   Hospital Vega Baja, Orihuela, Milla Madrigal Davinia ,   Hospital Vega Baja, Orihuela, Sánchez Hernández Antonio María ,   Hospital Vega Baja, Orihuela, Valoria Martínez Amadeo ,   Hospital Vega Baja, Orihuela
Published: November 2020

Objetivos: -Valorar la utilidad de las pruebas de neuroimagen funcional en consumidores crónicos de cocaína con trastornos del movimiento. -Evaluar la existencia de alteraciones neuropsicológicas permanentes tras abstinencia prolongada a cocaína. Material y métodos: Caso único (N=1). Varón de 41 años derivado por tics motores múltiples, espasmos mioclónicos, temblor distal de MMSS, ansiedad e insomnio de varios años de evolución. Antecedentes: hiperactividad/impulsividad y tics simples en la infancia no catalogados ni tratados. Consumo diario de THC y Cocaína vía inhalada desde los 18 años. Abstinencia a cocaína desde hace 6 años y THC hace un mes. Pruebas realizadas: -Dat-SCAN SPECT -Estado cognitivo general: Test MOCA, test de las FOTOS. -Atención: TMT y sustracciones. -Funciones ejecutivas: STROOP, WCST y test del reloj. -Memoria: dígitos directos e inversos. -Praxias: gesto simbólico, imitación de posturas. Resultados: -DaT-SCAN SPECT: alteración de la función dopaminérgica en la vía nigroestriada, predominante en núcleo caudado izquierdo y putamen derecho.	-Evaluación neuropsicológica: deterioro cognitivo leve. Alteraciones severas en funciones ejecutivas, leves en memoria remota. Normalidad resto de dominios. Descartamos síndrome de la Tourette por mala respuesta a Haloperidol y ausencia de criterios clínicos previos a 18 años. Tras el Dat-SCAN SPECT, se pautó Amisulpride (antipsicótico agonista parcial dopaminérgico) produciéndose franca mejoría de la clínica motora. Finalmente, se diagnosticó: “Trastorno mental específico después de daño cerebral orgánico (F07.9 CIE-10)” Conclusiones: -Estos hallazgos sugieren que, las pruebas de neuroimagen funcional que evalúan la vía dopaminérgica nigroestriada, son una herramienta útil para el diagnóstico diferencial de trastornos del movimiento secundarios al consumo crónico de cocaína, permitiendo orientar el tratamiento. -De los dominios evaluados, apreciamos especial afectación en funciones ejecutivas. Esto sugiere alteraciones más acusadas en sistemas dopaminérgicos prefrontales -A diferencia de otras dependencias, en la cocaína no parece que la abstinencia prolongada permita la recuperación total de las funciones cognitivas afectadas.
La adicción y la disociación: dos formas de evitación y afrontamiento. A propósito de un caso clínico.
Authors:   Hospital Clínic, Barcelona, Segú-Rosa Xavier , Martín-Villalba Inés ,   Hospital Clínic, Barcelona, Primé-Tous Mireia ,   Hospital Clínic, Barcelona, Gavín Patricia ,   Hospital Clínic, Barcelona
Published: November 2020

1.	Objetivos El presente pretende dar cuenta de la relación existente entre disociación y consumo de sustancias como estrategias que posee el individuo para afrontar de una forma aparentemente adaptativa a corto plazo, las distintas situaciones de la vida. Se nos presenta la peculiaridad de esta asociación a través de un caso clínico, donde su historia vital (influenciada por el trauma complejo), lleva a la paciente a funcionar en su medio a través de un tipo de afrontamiento peculiar. Las consecuencias de este estilo aprendido de actuar, como el lector podrá anticipar, son devastadoras para la persona a todos los niveles de su funcionamiento y en los distintos ámbitos de su vida. Con esta comunicación se pretende dar cuenta de la realización del diagnóstico y tratamiento de un caso complejo de psicopatología dual. 2.	Material y métodos Se aproxima el caso como un diseño experimental de tipo N=1 y el material de evaluación utilizado: STIPO-R, SCID-II, DIB-R, PID-5, CTQ, SCL-90, BIS-11, BPD checklist. 3.	Resultados y conclusiones Se realiza una aproximación terapéutica integral e intensiva en hospital de día basada en los distintos dominios de afrontamiento, gestión emocional y abordaje del consumo de distintas sustancias ( MDMA de forma puntual, trastorno por uso de cannabis, abuso de benzodiacepinas, abuso de alcohol…), así como estrategias dialectico-conductuales de validación y desescalamiento emocional que llevarán a la paciente a la propia comprensión de la patología y a una paulatina mejora en su nivel de afrontamiento y funcionalidad.
EL SUICIDIO Y SU RELACIÓN CON EL TRASTORNO POR USO DE SUSTANCIAS.
Authors:   Comunidad Terapéutica De Cartaya (ASSDA), CARTAYA, Fernández Rocha María Luisa , González Soriano Patricia ,   Comunidad Terapéutica De Cartaya (ASSDA), CARTAYA, Villas Palau Antonio ,   Comunidad Terapéutica De Cartaya (ASSDA), CARTAYA, Pérez Gómez Juana María ,   Comunidad Terapéutica De Cartaya (ASSDA), CARTAYA, Benítez Zamorano Manuel ,   Comunidad Terapéutica De Cartaya (ASSDA), CARTAYA
Published: November 2020

INTRODUCCIÓN: El suicidio, según la Organización Mundial de la Salud), es un problema mundial, que provoca cada año más muertes, que las causadas por guerras, asesinatos y desastres naturales. Son múltiples los factores de riesgo que propician una conducta suicida, y entre ellos cabe destacar, los trastornos por uso de sustancias (TUS). OBJETIVOS Conocer la evidencia actual sobre la relación entre suicidio y trastorno por consumo de sustancias. METODOLOGÍA Se ha realizado una búsqueda bibliográfica en PubMed utilizando las palabras claves suicide, suicide attempt, drugs, substance use disorder. El idioma utilizado ha sido el inglés, y se ha revisado la bibliografía de los últimos 5 años	RESULTADOS Según la bibliografía, los trastornos por uso de sustancias están asociados con un riesgo significativamente mayor de suicidio en ambos sexos, siendo aún más relevante, si hay un diagnóstico de múltiples trastornos por uso de sustancias (alcohol, cannabis, cocaína, opiáceos, anfetaminas etc). Sin embargo, hay otros estudios donde el riesgo relativo asociado con el TUS es particularmente alto para las mujeres. Estos datos pueden estar relacionados con la oposición de las mujeres a buscar ayuda para los trastornos asociados con el uso de sustancias en comparación con los hombres, de modo que las mujeres diagnosticadas están más afectadas. Las condiciones psiquiátricas también juegan un papel importante en la mortalidad por suicidio en las personas con TUS, aunque incluso controlando estas afecciones, los trastornos por uso de sustancia siguen siendo un factor de alto riesgo. CONCLUSIÓN Los trastornos actuales por uso de sustancias indican un aumento en el riesgo de suicidio. Este aspecto nos ayudará a detectar y prevenir el riesgo de suicidio en las personas diagnosticas de trastornos por consumo de sustancias cuando ingresan en los programas de tratamiento de uso de sustancias.
Análisis desde la perspectiva de género de una muestra de enfermos duales con trastorno de personalidad comórbido.
Authors:   Complejo Hospitalario Universitario de A Coruña, A Coruña, Muinelo Paula , Novo Ana ,   Centro de adicciones ACLAD , A Coruña, Castedo David ,   Complejo Hospitalario Universitario de A Coruña, A Coruña, Rodríguez Tania ,   Centro de adicciones ACLAD , A Coruña, Señoráns Darío , Isabel Campos Ana , Ortega Alejandra , Carrera Indalecio ,   Centro de adicciones ACLAD , A Coruña, Serrano Manuel ,   Complejo Hospitalario Universitario de A Coruña, A Coruña
Published: November 2020

1.	Descripción de los objetivos En la actualidad, la Patología Dual (PD) continúa sin aparecer recogida como entidad clínica en las principales clasificaciones internacionales, a pesar de las numerosas evidencias cientificas existentes. Nuestro objetivo es evaluar, desde una perspectiva de género, las características clínicas de pacientes con trastorno mental severo (TMS) incluidos en el programa con antipsicóticos inyectables de larga duración (APLD) , así como la seguridad, eficacia y eficiencia del APLD. 2.	Material y métodos Este estudio se enmarca en el proyecto “Evaluación de los pacientes a tratamiento en las redes asistenciales de adicciones de Galicia y norte de Portugal”, el cual obtuvo el dictamen favorable del Comité Ético de Investigación de Galicia y Oporto, así como su clasificación a la Agencia Española del Medicamento y Productos Sanitarios como "Estudio Posautorización de seguimiento prospectivo". Se trata de un estudio abierto, observacional, adoptando las condiciones habituales de la práctica clínica y con un período de seguimiento longitudinal de 6 meses. La muestra está compuesta por 147 pacientes con TMS, todos ellos bajo tratamiento con APLD en el centro de adicciones ACLAD de A Coruña. 3.	Resultados y conclusiones En nuestra muestra, el 86% presentaron un diagnóstico de TP; siendo un 81% hombres y el 19% restante mujeres. Los trastornos del Eje II fueron más frecuentes en mujeres, existiendo en ellas una mayor prevalencia de casos clasificados como Clúster B frente al diagnóstico más frecuente de TP-Mixto en varones. Con respecto a APLD, vemos mayor tendencia a uso de Aripiprazol en pacientes con diagnóstico del Eje II y, por consiguiente, en mujeres. Las características clínicas y parámetros sociales podrían ser diferentes en el subgrupo de mujeres, por lo que son necesarios más estudios de cara a un abordaje específico en pacientes duales mujeres con TP comórbido.
Biofertilizer in the control of the nematode Pratylenchus brachyurus in sugarcane crop
Authors: Silva Grasiele Teixeira da , Rios Anderli Divina Ferreira , Silva Rafael Matias da , Buso Wilian Henrique Diniz , Conceição Denise Rodrigues , Oliveira Rafaela Santos de 
Published: November 2020

Biofertilizers can also be used as plague and disease control agents. The commercial product Microgeo® is a biological biofertilizer rich in microorganisms. Few studies have been carried out to evaluate the interaction between biofertilizer and nematodes. The objective of this study was to evaluate the efficiency of the Microgeo® biological fertilizer to control the nematode Pratylenchus brachyurus in two sugarcane cultivars. The work was carried out in greenhouse conditions with a completely randomized experimental design (DIC), in a triple factorial scheme (2 x 2 x 4), being two types of sugar cane (CTC 04 and CTC 9003), two types of management of the biofertilizer (Management 1: application of the biofertilizer and inoculation of the nematode at 0 days after transplanting (DAT), management 2: application of the biofertilizer and inoculation of the nematode in the roots of the plant 30 days later) and four doses of the liquid biofertilizer Microgeo® (0 L ha‑1; 150 L ha-1; 300 L ha-1; 450 L ha-1), with four replications. 800 specimens of P. brachyurus were inoculated in each experimental plot. The results showed that cultivating CTC 9003 during the conduct of the experiment showed greater susceptibility to the nematode compared to cultivating CTC 04. The biofertilizer Microgeo® showed no curative or preventive effect on the control of the nematode under the conditions of the experiment.
Does nitrogen application timing and sources influence barley grain yield?
Authors: Besen Marcos Renan , Ribeiro Ricardo Henrique , Bratti Felipe , Locatelli Jorge Luiz , Piva Jonatas Thiago 
Published: November 2020

The suitable management of nitrogen (N) fertilization can increase barley grain yield, since it is the nutrient required in greater quantity. In this sense, the source and timing of nitrogen application are relevant factors. The objective was to evaluate the effects of N sources and splitting on the performance of barley. The experiment was carried out under a clayey Cambisol (550 g kg-1), in Curitibanos, Santa Catarina. Factorial randomized blocks were used: three mineral sources of N: urea (45% N); urea with urease inhibitor-NBPT (45% of N) and nitrate (30% of N), associated with two nitrogen splitting fertilization: i) split of the rate of N in two seasons: beginning of tillering and full tillering and ii) single application at full tillering. 100 kg ha-1 of N were applied. There was no interaction between the factors and there was no effect of treatments for plant height, ear length, grains per ear, ears per m² and mass of a thousand grains. Yield was influenced by the N source, where nitrate exceeded the yield from amidic sources by 16%. The splitting of N in two times did not present advantages over the single application. Urea with NBPT was not viable in relation to readily soluble forms of N, with the highest yield obtained with a nitric source.