bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between adherence to MIND diet and severity, duration and frequency of migraine headaches among migraine patients
Authors: Askarpour Moein , yarizadeh Habib , Sheikhi Ali , Khorsha Faezeh , Mirzaei Khadijeh 
Published: July 2020

AbstractObjectivesMigraine is a neurological disorder causing unbearable pain. Dietary approach is proposed as a preventive way of reducing the severity of migraine headaches. The present study aimed to examine the association between MIND diet and migraine headaches.ResultsWe found that participants with higher score of MIND diet compared to those with lower score, were less likely to have severe headaches (OR = 0.64; 95% CI 0.45, 0.91;P = 0.01). Moreover, our results showed an inversed correlation between mind diet score and duration (β = − 0.14, 95% CI − 1.42, − 0.14,P = 0.04) and frequency of headaches (β = − 0.13, 95% CI − 0.99, − 0.07,P = 0.03).
Follow-up after radiological intervention in oncology: ECIO-ESOI evidence and consensus-based recommendations for clinical practice
Authors: Maas Monique , Beets-Tan Regina , Gaubert Jean-Yves , Gomez Munoz Fernando , Habert Paul , Klompenhouwer Lisa G. , Vilares Morgado Paulo , Schaefer Niklaus , Cornelis Francois H. , Solomon Stephen B. , van der Reijd Denise , Bilbao Jose Ignacio 
Published: July 2020

AbstractInterventional radiology plays an important and increasing role in cancer treatment. Follow-up is important to be able to assess treatment success and detect locoregional and distant recurrence and recommendations for follow-up are needed. At ECIO 2018, a joint ECIO-ESOI session was organized to establish follow-up recommendations for oncologic intervention in liver, renal, and lung cancer. Treatments included thermal ablation, TACE, and TARE. In total five topics were evaluated: ablation in colorectal liver metastases (CRLM), TARE in CRLM, TACE and TARE in HCC, ablation in renal cancer, and ablation in lung cancer. Evaluated modalities were FDG-PET-CT, CT, MRI, and (contrast-enhanced) ultrasound. Prior to the session, five experts were selected and performed a systematic review and presented statements, which were voted on in a telephone conference prior to the meeting by all panelists. These statements were presented and discussed at the ECIO-ESOI session at ECIO 2018. This paper presents the recommendations that followed from these initiatives. Based on expert opinions and the available evidence, follow-up schedules were proposed for liver cancer, renal cancer, and lung cancer. FDG-PET-CT, CT, and MRI are the recommended modalities, but one should beware of false-positive signs of residual tumor or recurrence due to inflammation early after the intervention. There is a need for prospective preferably multicenter studies to validate new techniques and new response criteria. This paper presents recommendations that can be used in clinical practice to perform the follow-up of patients with liver, lung, and renal cancer who were treated with interventional locoregional therapies.
A glance on the role of actin in osteogenic and adipogenic differentiation of mesenchymal stem cells
Authors: Khan Asmat Ullah , Qu Rongmei , Fan Tingyu , Ouyang Jun , Dai Jingxing 
Published: July 2020

AbstractMesenchymal stem cells (MSCs) have the capacity to differentiate into multiple lineages including osteogenic and adipogenic lineages. An increasing number of studies have indicated that lineage commitment by MSCs is influenced by actin remodeling. Moreover, actin has roles in determining cell shape, nuclear shape, cell spreading, and cell stiffness, which eventually affect cell differentiation. Osteogenic differentiation is promoted in MSCs that exhibit a large spreading area, increased matrix stiffness, higher levels of actin polymerization, and higher density of stress fibers, whereas adipogenic differentiation is prevalent in MSCs with disrupted actin networks. In addition, the mechanical properties of F-actin empower cells to sense and transduce mechanical stimuli, which are also reported to influence differentiation. Various biomaterials, mechanical, and chemical interventions along with pathogen-induced actin alteration in the form of polymerization and depolymerization in MSC differentiation were studied recently. This review will cover the role of actin and its modifications through the use of different methods in inducing osteogenic and adipogenic differentiation.
BMMSC-sEV-derived miR-328a-3p promotes ECM remodeling of damaged urethral sphincters via the Sirt7/TGFβ signaling pathway
Authors: Zhang Hanke , Huang Jiayu , Liu Jiaying , Li Yanhui , Gao Ying 
Published: July 2020

Abstract
Background
Stress urinary incontinence (SUI) is a common and bothersome condition. Invasive surgery will always be considered after conservative treatment fails, but the rates of postoperative complications and long-term recurrence are high. Thus, a new treatment strategy is still needed. In recent years, bone marrow mesenchymal stem cells (BMMSC) have shown great promise for SUI treatment. The therapeutic effects of BMMSC on SUI are achieved mainly by paracrine pathway signaling molecules, such as small extracellular vesicles (sEV). sEV are recognized as essential mediators of cell-to-cell communication. However, the therapeutic effects and detailed mechanisms of BMMSC-derived sEV in SUI remain mostly unexplored.

Methods
The effects of BMMSC-sEV on extracellular matrix (ECM) metabolism were assessed in vitro and in vivo. In a SUI rat model, TGF-β1 signaling was examined with or without BMMSC-sEV stimulation. sEV miRNAs were deeply sequenced, and the most likely miRNAs were evaluated as mediators of the TGF-β1 signaling pathway.

Results
BMMSC-sEV enhanced the synthesis of ECM components, including elastin, collagen I, and collagen III, and improved urethral function. Furthermore, BMMSC-sEV activated TGF-β1 signaling in primary fibroblast cells and in rat urethras. Several differentially expressed miRNAs were identified in the BMMSC-sEV. Bioinformatics analysis and in vitro studies showed that BMMSC-sEV miR-328a-3p can be transferred from BMMSC to fibroblasts and can regulate the Sirt7/TGF-β1 signaling pathway.

Conclusion
BMMSC-sEV promote ECM remodeling of damaged urethral sphincters by transferring miR-328a-3p to regulate the Sirt7/TGF-β1 signaling pathway.
Health-related quality of life, self-reported impairments and activities of daily living in relation to muscle function in post-polio syndrome
Authors: Gocheva Vanya , Hafner Patricia , Orsini Anna-Lena , Schmidt Simone , Schaedelin Sabine , Rueedi Nicole , Rubino-Nacht Daniela , Weber Peter , Fischer Dirk 
Published: July 2020

Abstract
Background
The symptoms of post-polio syndrome (PPS) and its resulting disabilities can affect quality of life and the ability to perform daily activities. No study has comprehensively analysed how various patient-reported outcome measures (PROMs) are associated with objectively assessed physical function in patients with PPS.

Aim
To investigate health-related quality of life (HRQOL), self-reported impairments and activities of daily living during 6 months and evaluate their association with clinical muscle function outcomes in individuals with PPS.

Methods
Twenty-seven patients with PPS were included in the study. At baseline and 6 months, patients were administered PROMs measuring HRQOL (WHOQOL-BREF), self-reported impairments related to PPS (SIPP-RS) and activities of daily living (IBM-FRS). Clinical muscle function outcomes included 6 min walking distance (6MWD) and motor function measure (MFM).

Results
There were no changes in self-reported impairments (25.52 to 24.93, p = 0.40), activities of daily living (33.89 to 33.30, p = 0.20), 6MWD (391.52 to 401.85, p = 0.30) and MFM (83.87 to 85.46, p = 0.14) during 6 months, while the HRQOL psychological health decreased during this period (76.85 to 72.38, p = 0.05). A strong association was found between activities of daily living and clinical muscle function outcomes (6MWD: ß = 0.02, 95% CI: 0.02;0.03, t = 6.88, p < 0.01; MFM: ß = 0.25, 95% CI: 0.17;0.33, t = 6.69, p < 0.01). Self-reported impairments and HRQOL domains were not associated with the clinical muscle outcomes.

Conclusions
Study findings indicate that objectively measured walking and motor abilities do not reflect patient’s perspectives of their HRQOL and impairment due to PPS. More research is needed to assess changes over time and capture clinically meaningful changes in individuals with PPS and to increase the understanding of how the patient’s perspective of disability measured by PROMs is related to objectively measured walking and motor abilities.

Trial registration
ClinicalTrials.gov Identifier (NCT02801071) registered June 15, 2016.
Validity of fibromyalgia survey questionnaire (2016) assessed by telephone interview and cross-cultural adaptation to Brazilian Portuguese language
Authors: Daltrozo Jordana Bernardi , Paupitz Juliane Aline , Neves Fabricio Souza 
Published: July 2020

Abstract
Background
To verify the validity of the 2016-revised Fibromyalgia Survey Questionnaire (FSQ) by telephone interview compared to self-administration and to produce a valid version of FSQ in Brazilian Portuguese language.

Methods
The Brazilian version of FSQ was produced following the recommendations for cross-cultural adaptation. Validity of Brazilian FSQ self-administration was assessed by checking agreement of its results with fibromyalgia diagnosis according the 1990 American College of Rheumatology (ACR) criteria. Reproducibility and validity of FSQ by telephone were assessed by comparing its results with the previous FSQ self-administration.

Results
A Brazilian Portuguese version (FSQ-Brazil) was produced. FSQ-Brazil had good internal consistency (Cronbach’s alpha between 0.73 and 0.94). Agreement between the results obtained by self-administration of FSQ-Brazil and by telephone interview was substantial or almost perfect for almost all questions about pain sites and all questions about other somatic symptoms (Cohen’s kappa higher than 0.6). There were small but significant bias toward higher scores of widespread pain index and fibromyalgia severity scale in the telephone interview compared to self-administration. Fibromyalgia definition by self-administration and telephone interview with FSQ-Brazil both revealed substantial agreement with the diagnosis based on ACR 1990 criteria (Cohen’s kappa 0.62 and 0.65; respectively).

Conclusions
FSQ-Brazil demonstrated good internal consistency, reproducibility and validity both by self-administration and by telephone interview. However, caution must be taken with the interpretation of quantitative scores of widespread pain index and symptoms severity scale, which slightly differed according the method (self-administration or interview) in our study.
Geographic Diversification and Banks’ Funding Costs
Authors: Levine Ross , Lin Chen , Xie Wensi 
Published: July 2020

We assess the impact of geographic diversification on a bank’s costs of interest-bearing liabilities. We employ a new identification strategy and discover that geographic expansion across U.S. states lowered funding costs. Consistent with expansion facilitating risk diversification, we find that (1) funding costs fall more when banks expand into states whose economies are less correlated with the banks’ state and (2) geographic diversification reduces the costs of uninsured, but not insured, deposits. Consistent with expansion intensifying agency frictions, which puts upward pressures on funding costs, we discover that geographic diversification reduces the costs of interest-bearing liabilities more in better-monitored and better-run banks.This paper was accepted by Tomasz Piskorski, finance.
Prognostic value of severity of dislocation in late-detected developmental dysplasia of the hip
Authors: Terjesen Terje , Horn Joachim 
Published: July 2020

Purpose The aims of this study were to evaluate the reliability of three classifications of severity of dislocation in late-detected developmental dysplasia of the hip (DDH), especially to assess whether they are predictive of long-term outcomes. Methods Two groups of patients were analyzed. Group 1 (57 patients, 69 hips) underwent closed reduction between 1958 and 1962. Mean age at reduction was 20.3 months (4 to 65). Group 2 (50 patients, 54 hips) treated between 1996 and 2005, was used for analysis of the association between severity of dislocation and treatment (open or closed reduction). The primary radiographs were graded according to the Tönnis classification, the classification of the International Hip Dysplasia Institute and a new method based on the position of the most lateral point of the proximal femoral metaphysis (lateral metaphysis height classification, LMH). The outcome at a mean age of 51.2 years (55 to 60) was graded according to the occurrence of osteoarthritis (OA) and total hip arthroplasty (THA). Results There were significant associations between the classifications, and the intra- and interobserver agreements were high. More severe grades of DDH were significantly associated with age ≥ 18 months and with open reduction. None of the classifications were significantly associated with long-term OA. The LMH method was significantly associated with the need for THA, whereas the other classifications were not. Conclusion All the classifications were reliable in grading severity of DDH. The LMH method seems preferable in clinical practice because the main landmarks were easy to define and because it had long-term prognostic value. Level of Evidence III
Tunable plasmon-induced transparency with a dielectric grating-coupled graphene structure for slowing terahertz waves
Authors: Wang Tianzhi , Yan Fei , Wang Ruoxing , Tian Fengjun , Li Li 
Published: July 2020

We present a tunable plasmon-induced transparency (PIT) structure that is composed of dielectric grating and a graphene system to manipulate terahertz (THz) waves. The graphene system consists of a graphene sheet and a graphene ribbon layer, with a spacer between them. By exploiting the diffraction coupling of THz wave with dielectric grating, graphene plasmonic resonance is efficiently excited on both graphene sheet and graphene ribbons. This leads to the surface plasmon mode of the graphene sheet and the localized plasmon mode of the graphene ribbons. The coupling between the two-plasmon modes via near-field destructive interference generates a strong PIT effect with slowing the group velocity of THz waves. A group delay over 0.2 ps and group index beyond 170 can be achievable. The group slowing effect is dynamically tunable with varying the Fermi level of graphene. The work suggests a promising scheme for on-chip graphene slow-wave devices at the THz regime.
Il brand Gomorra: Dal romanzo alla serie TV, Giuliana Benvenuti (2018)
Authors: Moscardi Iuri 
Published: July 2020

Review of: Il brand Gomorra: Dal romanzo alla serie TV, Giuliana Benvenuti (2018)
Bologna: Il Mulino, 208 pp.,
ISBN 978-8-81527-433-5, p/bk, €19.00
È stata Roma: La criminalità capitolina dal ‘poliziottesco’ a Suburra, Matteo Santandrea (2019)
Authors: Renga Dana 
Published: July 2020

Review of: È stata Roma: La criminalità capitolina dal ‘poliziottesco’ a Suburra, Matteo Santandrea (2019)
Catanzaro: Rubbettino Editore, 212 pp.,
ISBN 978-8-84985-770-2, p/bk, €16.00
The talks on the Cyprus problem at Crans-Montana, Switzerland (28.06 – 07.07.17) and the Greek-Cypriot Press: The views of newspapers Alithia, Politis and Haravgi
Authors: Antoniades Euripides 
Published: July 2020

This paper focuses on the period of negotiations between the Greek-Cypriot and Turkish-Cypriot community at Crans-Montana, Switzerland, from 28 June to 7 July 2017. It looks into the views of the three leading Greek-Cypriot newspapers of that period and aims to present the positions of each newspaper about the negotiations on the Cyprus problem, at political level. Articles from three newspapers (Alithia, Politis and Haravgi) were studied, with an emphasis on political coverage regarding the negotiations. For the Crans-Montana negotiations on the Cyprus problem, the agenda setting approach was used, according to which, an event becomes an important from a journalist’s perspective, not only because it is unexpected and/ or dramatic, but also because it attracts a great deal of public attention and the significance of the event itself may, for example, lead to intense public judgment, tension or concerns. The research questions of the paper were shaped as follows: Τo what extent were the newspapers in favour of a solution to the problem? Did they have a conflicting or reconciling tone? To what extent did the style and tone of the news items regarding the talks vary depending on the newspaper? To what extent did the news items focus on persons taking part in the talks and the topics of the talks? Were the articles signed or not? Findings suggest that the Greek Cypriot press during the negotiations have faith that the Cyprus issue can be resolved through the talks. The overarching aim is to understand the efforts made to solve the Cyprus problem through the negotiations in Switzerland and to examine the positions of the Cypriot press regarding this thorny and crucial issue, over which the Republic of Cyprus has been agonising for more than forty years.
Aula de campo no projeto TAMAR: conscientizando alunos do nível 1 da educação infantil, sobre os cuidados e sobrevivência das tartarugas no habitat de proteção / Field lesson in the TAMAR project: raising awareness among students of level 1 of early childhood education about the care and survival of turtles in the protection habitat
Authors: Domingos Lucilene Emidio , Silva José Geraldo Ferreira da 
Published: July 2020

Alunos da Educação Infantil realizam atividades diversificadas dentro e fora de sala de aula juntos de seus professores, em espaços formal e não formal, levando consigo conhecimentos prévios para a aula de campo, onde expressaram suas curiosidades relacionadas ao meio ambiente que foram visitar. O objetivo deste artigo é conhecer a vida da tartaruga marinha; reconhecer algumas interações entre seres vivos e conscientizar sobre questões ambientais pensando na preservação da espécie animal e cuidados com o meio ambiente marinho através do projeto TAMAR. Para coleta de dados foram realizadas observações e desenvolvimentos de planejamentos com alunos do nível 1 por 10 dias letivos. Os dados que foram colhidos e analisados de forma descritivas e interpretativa. Conforme as aula iam acontecendo os alunos mostraram bastante interesse em conhecer e aprimorar os conhecimentos, o entusiasmo dos aluno foi ainda maior na aula de campo no Projeto TAMAR a sensibilização diante que eles viam foi verificado de acordo com as reações de gritos eufóricos, gargalhadas, perguntas a monitora do projeto TAMAR, admiração frente as informações recebidas e espanto visto que muitas tartarugas morem por causa do lixo que são jogados no mar.Palavras chave: Meio Ambiente. Educação Ambiental. Projeto TAMAR. Aula de Campo e Sensibilização.
Declínio do Número de Alunos da Escola Salesiana Padre Rinaldi: Uma proposta de Melhoria / Decline of the Number of Students of the Salesian School Padre Rinaldi: A Proposal for Improving
Authors: Lima Júnior José Lopes , Escudero Jaime Caiceo 
Published: July 2020

A Administração evolui com o tempo e desenvolve modelos de gestão que responde ao contexto temporal e socioeconômico em que a Organização está inserida. Administração Estatégica conjugada com Administração da Qualidade é um modelo de Gestão Contemporãneo. A proposta de melhoria proposta a Escola Salesiana Padre Rinaldi, visando reduzir ou parar o declínio do número de seus alunos tem estratégias nos âmbitos de pessoal, financeiro e pedagógico, fundadas numa Administração Estratégica e de Qualidade Total, com o envolvimento de todos os integrantes da Comunidade Educativo-Pastoral. Palavras chave: Administração. Administração Estratégica. Administração de Qualidade Total. Gestão de Pessoal. Gestão Financeira. Gestão Pedagógica. Estratégias. Comunidade Educativo-Pastoral (CEP).
Marked Elevation of Lipase in COVID-19 Disease: A Cohort Study
Authors: Barlass Usman , Wiliams Brett , Dhana Klodian , Adnan Darbaz , Khan Shahab R. , Mahdavinia Mahboobeh , Bishehsari Faraz 
Published: July 2020

INTRODUCTION:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the pandemic of coronavirus disease 2019 (COVID-19) is a global health crisis. Possible pancreatic involvement has recently been observed in these patients; however, its significance is unclear. The aim of this study was to evaluate the association of significantly elevated lipase with disease outcomes.

METHODS:
Data about demographics, symptoms, laboratory values, and clinical outcomes were collected for 1,003 consecutive patients testing positive for COVID-19. Elevated lipase was defined as greater than 3 times the upper limit of normal (>3 × ULN). Baseline characteristics among patients with or without elevated lipase were compared using Fisher exact test or Student t-test for categorical or numerical variables, respectively. Logistic regression was used to evaluate the association of lipase levels with primary clinical outcomes (intensive care unit admission and intubation) adjusted for age, sex, body mass index, history of diabetes, and hypertension.

RESULTS:
Of 1,003 patients with COVID-19, 83 had available lipase levels and were all admitted to the hospital. Of 83, 14 (16.8%) had elevated lipase (>3 × ULN), which was associated with higher rates of leukocytosis (P < 0.001) and abnormal liver enzymes (P < 0.01). Compared with lower lipase levels (<3 × ULN), patients with elevated lipase had higher rates of ICU admission (92.9% vs 32.8%; P < 0.001) and intubation (78.6% vs 23.5%; P 0.002). In a multivariable-adjusted model, higher lipase levels were significantly associated with admission to the ICU and rate of intubation.

DISCUSSION:
Lipase elevation is seen in COVID-19 and is associated with worse disease outcomes.
Aeromagnetic mapping of fault architecture along Lagos–Ore axis, southwestern Nigeria
Authors: Oladejo Olagoke Peter , Adagunodo Theophilus Aanuoluwa , Sunmonu Lukman Ayobami , Adabanija Moruffdeen Adedapo , Enemuwe Charity Adaeze , Isibor Patrick Omoregie 
Published: July 2020

AbstractA seismic wave is released when there is sudden displacement on a fault plane. The passage of this wave along the fault plane or within the lithosphere could result in ground shaking or vibration at the surface of the Earth. To provide a geophysical explanation to this phenomenon, the high-resolution aeromagnetic data of the sedimentary terrain and part of the Basement Complex of Southwestern Nigeria were processed and interpreted to provide fault architecture of the area, which could serve as conduit for the passage of seismic energy in the study area. High-resolution aeromagnetic data along the Lagos–Ore axis are processed for fault mapping in the study area. The reduced-to-equator (RTE) residual aeromagnetic data used were enhanced using the total horizontal derivative (THD) and upward continuation (UC) filtering techniques on Oasis Montaj 6.4.2 (HJ) software. The resultant maps were overlaid and compared with the plotted RTE residual maps for relevant interpretations. Varying signatures of magnetic anomalies are grouped into high (57.9–89.1 nT), intermediate (38.2–57.9 nT), and low (4.0–38.2 nT) magnetic intensities, which are associated with contracting basement rocks features. The obtained lineaments from the THD reveal areas of various deformations such as brittle, which is associated with faults/fractures, and ductile deformation, which is associated with folds of geological features. The faults, as depict by the UC map, reveal different depth ranges of 500–2250 m at the western side and 1,500–1,250 m at the northwestern area of the study. Since it has been on record that September 11, 2009, earth tremor of magnitude 4.4, with the epicenter at Allada, Bennin Republic, 128 km west of Lagos, Nigeria occurred within the study area, it can be inferred that the established geologic fault architecture could be responsible for the hazard and be part or synthetic to the Ifewara-Zungeru fault in Nigeria.