bluuebunny/crossref_metadata_2025_split huggingface dataset:
Un paseo por los paisajes poéticos de Antonio Gala: El poema de Tobías desangelado en clave de lírica de viajes
Authors: Plaza González Pedro J. 
Published: January 2021

Frente a su producción teatral o a sus novelas, la poesía de Antonio Gala ha sido mucho menos estudiada por la academia. En este artículo se realiza un acercamiento a la poesía de Gala, en concreto a su libro El poema de Tobías desangelado (2005), proponiendo una lectura, entre otras posibles, del poemario, que es una peregrinatio vitae y una peregrinatio amoris, en clave de lírica de viajes en particular y en clave de literatura de viajes en general. Para ello, tomando como referencia principal el trabajo de Idoia Arbillaga, se analiza y ejemplifica la concreción de las cuestiones retóricas propias del género presentes en el texto —inventio, dispositio, elocutio, etcétera— y se recopilan y organizan todos los elementos relativos al viaje, al paseo y al paisaje que Gala reúne en sus poemas —los vehículos utilizados, el contacto con otras culturas, sus religiones, sus monumentos, el compañero de peripecias, etcétera—.
Compared to his theatrical production or his novels, Antonio Gala’s poetry has been much less studied by the academy. In this article, an approach to Gala’s poetry is made, specifically to his book El poema de Tobías desangelado (2005), proposing a reading, among other possible ones, of the book of poems, which is a peregrinatio vitae and a peregrinatio amoris too, in terms of travel lyric poetry in particular and in terms of travel literature in general. To do this, taking the work of Idoia Arbillaga as the main reference, the specific rhetorical issues of the genre present in the text are analyzed and exemplified —inventio, dispositio, elocutio, etc.— and all the elements related to the trip, also to the path and to the landscape, that Gala gathers in his poems, are collected and organized —the vehicles used, the contact with other cultures, their religions, their monuments, the companion, and so on—.
Los clubes deportivos de natación de Cataluña en el actual contexto competitivo del sector de las instalaciones deportivas
Authors: Santacruz Lozano JA. , Clemente Remón AL. , Jiménez-Beatty Navarro JE. , Jiménez Díaz-Benito V. 
Published: January 2021

Los clubes de natación son entidades sin ánimo de lucro con fines deportivos y sociales. El objetivo general del estudio fue conocer la gestión de los clubes de natación en Cataluña cumpliendo su función social y deportiva en el actual entorno competitivo de instalaciones deportivas. Los objetivos específicos fueron conocer sus valores en indicadores de gestión, así como saber si existen diferencias significativas entre los clubes según sus espacios y oferta deportiva. La muestra del estudio ha sido formada por 19 clubes deportivos de natación de Cataluña. El instrumento de recogida de datos fue un cuestionario adaptado a los objetivos del estudio, administrado por correo electrónico a los gerentes de cada club. Los clubes obtienen los ingresos necesarios para lograr sus fines deportivos y sociales gracias a las cuotas de sus socios. Se encontraron diferencias significativas entre ellos según los espacios y oferta deportiva en diferentes indicadores de gestión analizados.
Swimming clubs are non-profit entities for sports and social purposes. The general objective of the study was to know the management of swimming clubs in Catalonia, fulfilling their social and sports role in the current competitive environment of sports facilities. As specific objectives were to know their values on management indicators, as well as to know if significant differences between swimming clubs are found, taking in consideration their areas and sports offer. The study sample consists of 19 swimming clubs of Catalonia. The data collection instrument was a questionnaire adapted to the objectives of the study, administered by email to the managers of each club. The clubs obtain the necessary income to achieve their sporting and social goals thanks to the fees of their members. It was found significant differences between them according to the spaces and sports offer in different management indicators analyzed.
Revisión sistemática sobre los beneficios psicosociales obtenidos con intervenciones para promover el desplazamietno activo al colegio
Authors: Cerro Herrero D. , Tapia Serrano MA. , Vaquero Solis M. , Prieto Prieto J. , Sánchez Miguel PA. 
Published: January 2021

El desplazamiento activo al centro educativo ha disminuido en los últimos años. Los objetivos principales de esta revisión fueron determinar qué intervenciones se están llevando a cabo para promover el desplazamiento activo, conocer la calidad de las investigaciones y analizar qué parámetros psicosociales se han estudiado. La búsqueda bibliográfica se realizó en las bases de datos de Medline, Sport Discus, Scopus, Web of Science y Google Scholar. Finalmente, se seleccionaron 23 investigaciones que desarrollaban intervenciones para fomentar el desplazamiento activo. La intervención más frecuente es implementar programas para promover el desplazamiento activo (91.30%). Existen pocos estudios con intervenciones, y aproximadamente la mitad de los estudios no logran mejorar los datos de niveles de desplazamiento activo (47.83%). La salud psicosocial no ha sido apenas estudiada, tan solo en 1 estudio se midieron las variables de salud psicosocial. Es importante aumentar el número de estudios, aleatorizarlos, controlar contaminantes externos, aumentar la duración y desarrollar estudios de salud psicosocial.
Active commuting to schools has decreased in the last few years. The main objectives of this review were to determine which interventions are being carried out to promote active commuting, to know the quality of the research, and to analyze which psycosocial parameters can be improved. The bibliographic search was carried out in the databases of Medline, Sport Discus, Scopus, Web of Science, and Google Scholar... Finally, there were selecting a total of 23 investigations. The most frequent action is to implement programs to promote active commuting (91.30%). There are few data as yet on interventions, and approximately half of the studies fail to improve active commuting data (47.83%). Psychosocial health is not just studied only 1 study tested variables of psychosocial health. It is important to increase the number of studies, to randomize them, control external contaminants, increase the duration, and increase the psychosocial health studies.
Research on the measurement of intracranial hemorrhage in rabbits by a parallel-plate capacitor
Authors: Bai Zelin , Li Haocheng , Chen Jingbo , Zhuang Wei , Li Gen , Chen Mingsheng , Xu Jia , Zhao Shuanglin , Liu Yuening , Sun Jian , Wang Feng , Xu Lin , Qin Mingxin , Jin Gui 
Published: January 2021

Intracranial hemorrhage (ICH) carrying extremely high morbidity and mortality can only be detected by CT, MRI and other large equipment, which do not meet the requirements for bedside continuous monitoring and pre-hospital first aid. Since the biological tissues have different dielectric properties except the pure resistances, and the permittivity of blood is far larger than that of other brain tissues, here a new method was used to detect events of change at the blood/tissue volume ratio by measuring of the head permittivity. In this paper, we use a self-made parallel plate capacitor to detect the intracranial hemorrhage in rabbits by contactless capacitance measurement. The sensitivity of the parallel-plate capacitor was also evaluated by the physical solution measurement. The results of physical experiments show that the capacitor can distinguish between three solutions with different permittivity, and the capacitance increased with the increase of one solution between two plates. At the next step in the animal experiment, the capacitance changes caused by 2 ml blood injection into the rabbit brain were measured. The results of animal experiments show that the capacitance was almost unchanged before and after the blood injection, but increased with the increase of the blood injection volume. The increase of capacitance caused by blood injection was much larger than that before and after blood injection (P < 0.01). The experiments show that this method is feasible for the detection of intracranial hemorrhage in a non-invasive and contactless manner.
The average copy number variation (CNVA) of chromosome fragments is a potential surrogate for tumor mutational burden in predicting responses to immunotherapy in non‐small‐cell lung cancer
Authors: Lei Yuanyuan , Zhang Guochao , Zhang Chaoqi , Xue Liyan , Yang Zhenlin , Lu Zhiliang , Huang Jianbing , Zang Ruochuan , Che Yun , Mao Shuangshuang , Fang Lingling , Liu Chengming , Wang Xinfeng , Zheng Sufei , Sun Nan , He Jie 
Published: January 2021

AbstractObjectivesThe tumor mutational burden (TMB) is closely related to immunotherapy outcome. However, the cost of TMB detection is extremely high, which limits its use in clinical practice. A new indicator of genomic instability, the average copy number variation (CNVA), calculates the changes of 0.5‐Mb chromosomal fragments and requires extremely low sequencing depth.MethodsIn this study, 50 samples (23 of which were from patients who received immunotherapy) were subjected to low‐depth (10X) chromosome sequencing on the MGI platform. CNVA was calculated by the formula avg (abs (copy number‐2)). In addition, CNVA and TMB were compared with regard to their ability to predict immune infiltration in 509 patients from TCGA.ResultsThe high‐CNVA group had higher expression levels of PD‐L1, CD39 and CD19 and a higher degree of infiltration of CD8+ T cells and CD3 + T cells. Among the 23 patients treated with immunotherapy, the average CNVA value of the stable disease/partial response group was higher than that of the progressive disease group (P < 0.05). Whole‐genome sequencing data of 509 patients from TCGA and RT‐PCR results of 22 frozen specimens showed that CNVA is more effective than TMB in indicating infiltration of CD8+ T cells and expression of PD‐L1, and CNVA also showed a specific positive correlation with TMB (r = 0.2728, P < 0.0001).ConclusionsCopy number variation can be a good indicator of immune infiltration and immunotherapy efficacy, and with its low cost, it is expected to become a substitute for TMB.
Design, synthesis, molecular docking, anti‐quorum sensing, and anti‐biofilm activity of pyochelin‐zingerone conjugate
Authors: Nosran Anu , Kaur Parleen , Randhawa Vinay , Chhibber Sanjay , Singh Vasundhara , Harjai Kusum 
Published: January 2021

AbstractIn this article, we report the chemical synthesis of pyochelin‐zingerone conjugate via a hydrolysable ester linkage for drug delivery as a “Trojan Horse Strategy.” It is a new therapeutic approach to combat microbial infection and to address the issue of multi drug resistance in Gram‐negative, nosocomial pathogen Pseudomonas aeruginosa. Pyochelin (Pch) is a catecholate type of phenolate siderophore produced and utilized by the pathogen P. aeruginosa to assimilate iron when colonizing the vertebrate host. Zingerone, is active component present in ginger, a dietary herb known for its anti‐virulent approach against P. aeruginosa. In the present study, zingerone was exploited to act as a good substitute for existing antibiotics, known to have developed resistance by most pathogens. Encouraging results were obtained by docking analysis of pyochelin‐zingerone conjugate with FptA, the outer membrane receptor of pyochelin. Conjugate also showed anti‐quorum sensing activity and also inhibited swimming, swarming, and twitching motilities as well as biofilm formation in vitro.
The fragmentation of international banking regulation
Authors: Jabbour Ravel Sami 
Published: January 2021

AbstractAs in many areas of international law, the virus of fragmentation has now permeated the zeitgeist of international banking regulation. As a result, one of the largest pieces of regulation, the Basel III framework, hangs in the balance as it awaits implementation. This study assesses the financial sectors of both developed and emerging economies with an aim to determine which countries are more likely to spread the virus so that it can be stopped before becoming a pandemic. We find that a specific set of countries are most likely to do just that.
Effect of augmented reality on school journalism: A tool for developing communication competencies in virtual environments
Authors: Fernández‐García Carlos 
Published: January 2021

AbstractAugmented reality combines virtual and real elements within the same visual environment. It is urgently necessary that augmented reality be incorporated into public education in developing countries. This challenge requires governments to be committed to education. Nevertheless, within our nations, there exists an emerging body of expertise concerning the innovation of educational material utilizing Information and Communication Technology (ICT). The objective of this study is to explain how the use of augmented reality in school journalism affects the development of communication skills in virtual environments within the context of public secondary education in Latin America. This quasi‐experimental research study was conducted on two separate groups: an experimental group and a control group. The approach was a mix of qualitative and quantitative methodology. The results differed markedly between the two groups. The students in the experimental group developed the four communication skills in virtual environments at an average level of 95%, and they created an augmented reality magazine. Meanwhile, the control group did not even create a printed publication. It is concluded that the use of augmented reality makes a significant pedagogical contribution to the teaching/learning process of school journalism and that with the help of educational policies, this pedagogical contribution can be replicated in other schools.
Computational investigation of the substituent effect in the [2 + 4] Diels–Alder cycloaddition reactions of HSi≡Si(para‐C6H4X) with benzene
Authors: Ahraminejad Mina , Ghiasi Reza , Mohtat Bita , Ahmadi Roya 
Published: January 2021

AbstractIn this paper, the DFT method was applied at the B3LYP/6–311+G (d,p) level of theory to investigate the [2 + 4] Diels−Alder cycloaddition reactions of HSi≡Si(para‐C6H4X); X = NH2, OH, Me, H, F, CCH, OCF3 with benzene. It was attempted to show how the substituent affects the barrier height and thermodynamic parameters of these reactions. To illustrate the interaction between two fragments at transition states Activation Strain Model (ASM) and Energy Decomposition Analysis (EDA) were utilized. The Wiberg bond indices were used to check the progress of the reactions. The rate constant of the reaction was computed at 300 K, in the gas phase. Also, the synchronicity values of this reaction were determined.
Hydrogen detection properties of palladium sputtered polyacrylonitrile nanofibrous layers
Authors: Ahmadi Mahsa , Tavanai Hossein , Ranjbar Mehdi , Goodarzi Mehdi Torabi 
Published: January 2021

AbstractIn this research, electrospun polyacrylonitrile (PAN) nanofibrous layers are investigated as substrate for palladium‐based resistive type hydrogen sensors. The fabricated sensors showed sensitivity to hydrogen with a concentration as low as 12 ppm at room temperature. Up to 50 ppm hydrogen concentration, hydrogen induced lattice expansion (HILE) constituted the mechanism, whereas, with concentrations of 125 ppm and higher, palladium hydride formation (PdHx) mechanism ruled. For equal palladium thickness, the response of the sensors increased with increasing nanofiber diameter. With constant diameter of nanofibers, response and response time increased with thicker palladium layer. The sensor with 104 nm nanofibers and 4 nm palladium layer showed the best behavior. The sensor with nanofibrous substrate showed a higher response and lower response time in comparison to glass, PAN film, and PAN fibrous (fiber diameter: 16 μm, non‐nanofiber) substrate.
An unusual presentation of a hepatic ductal malformation in a Boxer dog
Authors: Kaniok Heidi , Gonzalez‐Gasch Esteban , Alloway Elizabeth , Suarez‐Bonnet Alejandro 
Published: January 2021

AbstractAn 11‐year‐old male neutered Boxer presented for evaluation of an external ear canal mass, postoperatively diagnosed as a benign inflammatory lesion. Preoperative staging of the ear mass identified a 10‐cm mass affecting the majority of the left lateral hepatic lobe, with inconclusive cytology. A left lateral liver lobectomy was performed. Histopathology revealed the hepatic parenchyma was largely effaced and replaced by a myriad of small calibre tubules lined by well‐differentiated biliary epithelium (cytokeratin19 and cytokeratin7 positive (CK19+, CK7+) supported by abundant fibrosis. Small cords and islands of hepatocytes (hepatocyte paraffin1 positive) (HepPar1+) were entrapped throughout these bile ducts. Analysis of the proliferation index via antigen KI‐67 (Ki67) immunohistochemistry confirmed lack of proliferative activity. Histological and immunohistochemical features were consistent with a ductal plate malformation (DPM). This is the first time a DPM of this size has been described on a computed tomography (CT) scan.
Access to Biomedical Research Material and the Right to Data Protection in Finland
Authors: Southerington Tom 
Published: January 2021

AbstractThis chapter describes the Finnish regulatory landscape concerning primarily non-interventional biomedical research and in particular the rights of study subjects from the data protection point of view. The GDPR is just one of many pieces of legislation affecting the rights of individuals, and it allows for significant variation between the EU Member States. Finnish law relating to biomedical research has materially changed in recent years and some changes are still pending. Overall, the legislator has aimed at enhancing opportunities for responsible research and enabling research-related innovation ecosystems, but also implemented quite strict limitations for data processing in balance. It is yet too early to evaluate the effects of the legislatory changes. The chapter is therefore mainly descriptive.
Mapping the Biobank Landscape in Greece
Authors: Tzortzatou Olga , Siapka Anastasia 
Published: January 2021

AbstractThe biobank landscape in Greece is mainly defined by tissue and data collections created in the course of clinical practice whose samples are subsequently repurposed for research. Given that there is no specific Greek biobank law, these collections have been so far governed through provisions drawn from the domestic civil and constitutional legal armamentarium concerning (biomedical) research as well as soft and hard EU and international laws. This chapter provides an empirical overview of the biobank landscape in Greece, describing existing biobanks and tissue collections potentially used for research in a non-exhaustive manner. Next, it explores how the Greek Law on the Protection of Personal Data envisages individuals’ rights in the context of biobanking research and how these rights are weighted against the public interest. Finally, it evaluates the potential impact of the GDPR on biobanking in Greece.
The Impact of the GDPR on the Governance of Biobank Research
Authors: Shabani Mahsa , Chassang Gauthier , Marelli Luca 
Published: January 2021

AbstractGovernance of health and genomic data access in the context of biobanking is of salient importance in implementing the EU General Data Protection Regulation (GDPR). Various components of data access governance could be considered as ‘organizational measures’ which are stressed in the Article 89(1) GDPR together with technical measures that should be used in order to safeguard rights of the data subjects when processing data under research exemption rules. In this chapter, we address the core elements regarding governance of biobanks in the view of GDPR, including conditions for processing personal data, data access models, oversight bodies and data access agreements. We conclude by highlighting the importance of guidelines and policy documents in helping the biobanks in improving the data access governance. In addition, we stress that it is important to ensure the existing and emerging oversight bodies are equipped with adequate expertise regarding using and sharing health and genomic data and are aware of the associated informational risks.
Competencies, Culture, and Change: A Model for Digital Transformation in K-12 Educational Contexts
Authors: Elkordy Angela , Iovinelli Jessica 
Published: January 2021

AbstractOn the surface, adopting technology presents itself as a technical issue. Yet, the real challenge of digital transformation in educational contexts necessitates a second-order change to disrupt and realign interconnected systems. A significant component of digital transformation in K-12 schools is an understanding of the unique affordances of digital tools and technologies and how these can be leveraged to align with learning goals and targets to impact teaching and learning in new ways. While there are several models for innovation diffusion and technology adoption in K-12 contexts, they fall short, particularly in describing the nature and interactions of these interconnected systems. These aspects of technology implementation remain a mystery. As a result, efforts to enact change in K-12 organizations often fall short due to a lack of understanding of context, inadequate goal-setting, insufficient professional development and personalized supports to build capacity, and a failure to evaluate progress. In K-12 educational settings, the people, the competencies, and the culture, alongside the strong leadership, resources, and organizational context, are all essential to effect sustainable change. We propose a model for digital transformation that considers all of these factors and interconnected systems.
Multi-Stakeholder Dialogues as Instrument for Design and Qualitative Research in Educational Organisations
Authors: Helbig Christian , Hofhues Sandra , Lukács Bence 
Published: January 2021

AbstractThe article focuses on the value of group discussions both as a method of organisational development and as a method of empirical social research. These two perspectives are discussed as a “double meaning”, which often occurs simultaneously in different forms. The concept of “multi-stakeholder dialogues” takes up this challenge. Following on from this, dimensions of the design and research of group discussions will be discussed. The contribution relates to the subproject “Multi-stakeholder Dialogues and Qualitative Evaluation” of the joint project “#ko.vernetzt”. The subproject had the task of accompanying, structuring and researching organisational development in a networked educational institution with dialogue formats. A total of nine dialogues were conducted with different groups of participants, six of which were analysed using qualitative methods. The research perspective is based on a concept of organisations from a praxeological perspective and an understanding of organisational culture as collective conjunctive experience. Thus, the object of qualitative research is the reconstruction of typical modus operandi of the processing of requirements. The results show that structural deficits in educational organisations are reproduced and reinforced by digitisation.