bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ascites management by cell-free concentrated ascites reinfusion therapy during recovery from drug-induced acute liver injury: a case report
Authors: Yasuda Koya , Asou Mea , Asakawa Tomohiko , Araki Makoto 
Published: October 2020

Abstract
Background
The symptoms of drug-induced hepatic injury are manifold; however, the presence of ascites indicates a severe disease condition. The rapid accumulation of ascites is distressing and requires palliative treatment. Because many cases are addressed by repeated large-volume paracentesis, often resulting in impairment due to protein and electrolyte loss, a different approach is required.

Case presentation
A 61-year-old Japanese man on maintenance dialysis was admitted to our hospital with acute liver injury. Our patient was diagnosed as having drug-induced liver injury due to warfarin or diltiazem, which started immediately after coronary artery bypass grafting 7 months previously. One month after admission, our patient’s hepatic encephalopathy remained grade 1 and his prothrombin time international normalized ratio was maintained at < 1.5. However, the liver was markedly atrophied with massive ascites. Although liver transplantation was desired, he was considered unfit for transplantation because of his renal and cardiac complications. Therefore, we devised a strategy to manage the massive ascites with cell-free concentrated ascites reinfusion therapy while awaiting liver regeneration. At first, cell-free concentrated ascites reinfusion therapy was required frequently because ascites accumulated rapidly. But the fluid retention interval was gradually extended as intended, and cell-free concentrated ascites reinfusion therapy was withdrawn after 8 months. During that time, the size of his liver increased from 1419 cm3 to 1587 cm3 on computed tomography.

Conclusions
Cell-free concentrated ascites reinfusion therapy is an apheresis therapy in which ascites are collected aseptically by paracentesis, concentrated, and then reinfused intravenously. This treatment has the advantage of preserving nutrition by reusing the fluid. Previously, cell-free concentrated ascites reinfusion therapy was used only for the management of ascites in patients with cirrhosis or carcinomatous peritonitis. This case suggests that palliation and maintenance of nutritional status with cell-free concentrated ascites reinfusion therapy may be useful as an adjunct to liver regeneration in drug-induced hepatic injury.
Case study: evaluation of the automation of material handling with mobile robots
Authors: Melo Adriana F. , Corneal Lindsay M. 
Published: October 2020

Abstract
The automation of material handling is one of the solutions that many companies are relying on to reach their goals related to productivity increment, floor space optimization, higher standards for factory’s safety, and allocation of workers to value-added activities. Therefore, the objective of this study was to evaluate the current state of the material flow of finished goods for an automotive parts supplier plant and the technology available on the market to verify if it was worthwhile to invest in material handling automation. The analysis included the use of discrete event simulation to evaluate the different layout approaches combined with the mobile robots’ performance. It was proven that the tandem layout was the most beneficial approach to the analyzed plant’s reality with a minimal of three robots. Improvements to the material flow and automation of the labeling process were also proposed based on the study.
Spousal violence and its determinants among married adolescent girls in Upper Egypt
Authors: El-Gazzar Amira F. , Aziz Mirette M. , Mohammed Heba M. , Elgibaly Omaima , Darwish Manal M. 
Published: October 2020

AbstractIntroductionIn Egypt, many girls are still married before the age of 18, which is a fundamental violation of the girls’ human rights. Early marriage is associated with an alarmingly elevated risk of all types of intimate partner violence that have various negative consequences. The purpose of this study was to identify the predictors of exposure to spousal violence among the early married girls in rural Upper Egypt.MethodsA household survey was carried out and covered 23 villages in Assiut and Sohag governorates reaching to a sample of 729 married girls before the age of 20. Listing and enumeration of 4 districts was done to identify the study participants. Data was collected by personal interviews using a structured questionnaire. Bivariate and stepwise regression analyses were performed to identify the predictors of exposure to spousal violence.ResultsIt was found that 15.2% of the study participants were exposed to physical violence while 17.8% were exposed to sexual violence and 7.3% were exposed to both types. Girls married before the age of 18 were more exposed to spousal violence. Stepwise regression analysis found that girls’ acceptance to get married was a protective factor against exposure to physical (β= − 1.07, OR 0.34) and sexual (β= − 0.68, OR 0.51) violence. The perceived attitude of husbands and mothers-in-law about considering wife beating “a husband's right” was found to be a risk factor of exposure to physical and sexual violence. Longer duration till the first pregnancy was also associated with more exposure to sexual violence (β= 0.04, OR 1.04).ConclusionMarried adolescent girls (MAGs) are highly exposed to physical and sexual violence. This is mainly due to ignoring girls’ preference to postpone their marriage, cultural concepts of accepting violence against women, and low sexual satisfaction. This study shows that most determinants of spousal violence were related to culture issues. Identifying these determinants is required to combat such a crucial public health problem that has serious consequences on adolescent health.
Lesion load assessment among multiple sclerosis patient using DIR, FLAIR, and T2WI sequences
Authors: Almutairi Abdullah Dhaifallah , Hassan Hasyma Abu , Suppiah Subapriya , Alomair Othman I. , Alshoaibi Abdulbaset , Almutairi Hajab , Mahmud Rozi 
Published: October 2020

AbstractBackgroundMagnetic resonance imaging (MRI) is one of the diagnostic imaging modalities employing in lesion detection in neurological disorders such as multiple sclerosis (MS). Advances in MRI techniques such as double inversion recovery (DIR) made it more sensitive to distinguish lesions in the brain. To investigate the lesion load on different anatomical regions of the brain with MS using DIR, fluid attenuated inversion recovery (FLAIR) and T2-weighted imaging (T2WI) sequences. A total of 97 MS patients were included in our retrospective study, confirmed by neurologist. The patients were randomly selected from the major hospital in Saudi Arabia. All images were obtained using 3T Scanner (Siemens Skyra). The images from the DIR, FLAIR, and T2WI sequence were compared on axial planes with identical anatomic position and the number of lesions was assigned to their anatomical region.ResultsComparing the lesion load measurement at various brain anatomical regions showed a significant difference among those three methods (p< 0.05).ConclusionDIR is a valuable MRI sequence for better delineation, greater contrast measurements and the increasing total number of MS lesions in MRI, compared with FLAIR, and T2WI and DIR revealed more intracortical lesions as well; therefore, in MS patients, it is recommended to add DIR sequence in daily routine imaging sequences.
In Vivo Predictive Dissolution Testing of Montelukast Sodium Formulations Administered with Drinks and Soft Foods to Infants
Authors: Martir J. , Flanagan T. , Mann J. , Fotaki N. 
Published: October 2020

AbstractIn vitro dissolution testing conditions that reflect and predict in vivo drug product performance are advantageous, especially for the development of paediatric medicines, as clinical testing in this population is hindered by ethical and technical considerations. The aim of this study was to develop an in vivo predictive dissolution test in order to investigate the impact of medicine co-administration with soft food and drinks on the dissolution performance of a poorly soluble compound. Relevant in vitro dissolution conditions simulating the in vivo gastrointestinal environment of infants were used to establish in vitro-in vivo relationships with corresponding in vivo data. Dissolution studies of montelukast formulations were conducted with mini-paddle apparatus on a two-stage approach: infant fasted-state simulated gastric fluid (Pi-FaSSGF; for 1 h) followed by either infant fasted-state or infant fed-state simulated intestinal fluid (FaSSIF-V2 or Pi-FeSSIF, respectively; for 3 h). The dosing scenarios tested reflected in vivo paediatric administration practices: (i.) direct administration of formulation; (ii.) formulation co-administered with vehicles (formula, milk or applesauce). Drug dissolution was significantly affected by co-administration of the formulation with vehicles compared with after direct administration of the formulation. Montelukast dissolution from the granules was significantly higher under fed-state simulated intestinal conditions in comparison with the fasted state and was predictive of the in vivo performance when the granules are co-administered with milk. This study supports the potential utility of the in vitro biorelevant dissolution approach proposed to predict in vivo formulation performance after co-administration with vehicles, in the paediatric population.
Protestant Rites and the Problem of Religious Difference in Colonial Korea
Authors: Jun Hajin 
Published: October 2020

AbstractColonial Korean society was a crucible of ritual conflict and innovation. The confluence of Protestant expansion, Japanese colonization, and cultural nationalism during the early twentieth century brought sweeping changes to Korean ritual life, especially to the all-important Confucian rites of passage. This article examines print media discussions of Protestant rites from the late 1910s to the early 1930s to trace how religious difference emerged as a political problem for Korean cultural nationalists. Early on, Protestant missionaries had banned ancestral veneration and other folk customs while spreading liturgical (marriage and funerary) ceremonies, in an effort to inculcate orthodox doctrines among new believers. Converts’ rejection of indigenous Confucian rites in favor of their own practices, however, soon became the focal point of heated public debates. When Protestants condemned ancestral rites as idolatry, they maligned fellow Koreans as primitive. Meanwhile, the rapid proliferation of Western-style church weddings excessively disseminated religious practices. Above all, cultural nationalists grew alarmed at how faith communities threatened to splinter society, diverting Koreans away from national concerns toward sectarian interests. I argue that Protestant rites prompted nationalist intellectuals to grapple with the sacred and secular, ultimately producing a narrow vision of religion subsumed under the aegis of the nation.
Social Media and Orthodontics
Authors: Frawley Tom , Scott Paul , Shelton Andrew , Smith Alastair 
Published: October 2020

Social media has become increasingly relevant to Orthodontics in several ways. This article highlights how both current and prospective patients may utilize social media to access information about, and voice their experiences of, orthodontic treatment. The applications of this to orthodontic research will also be discussed. Orthodontists should be aware of the role of social media in both education and marketing, as well as the current guidance and best practice in these areas. This knowledge should enable clinicians to maximize the advantages and avoid the pitfalls of social media in day-to-day life. CPD/Clinical Relevance: Clinicians should be aware of the potential impact of social media on education, research, marketing and patients' experiences of treatment.
Do stays abroad increase intercultural and general competences, affecting employability?
Authors: Genkova Petia , Kruse Lisa 
Published: October 2020

AbstractWith a globalized and growing world market, companies and educational institutions are getting more and more ambitious to re-orient their work patterns to the international level. Universities reacted to the demands of the globalized economy for flexibility and adaptability by the internationalization of their study programs. Research question: Do stays abroad and therefore intercultural experiences of students actually promote occupational competences and personal development? Design: In order to investigate this relationship, an online survey was employed, and a sample of N = 367 students, who had spent at least one semester abroad before, was recruited. The questions were aimed at measuring characteristics of the participants’ stays abroad, as well as occupational engagement, resilience, intercultural competence personality characteristics related to job performance. Results: The findings suggest that experience abroad can partly enhance employability by serving as an additional job qualification. The results reveal that people who have experienced a stay abroad show higher work and study commitment and are more ambitious regarding their work. Furthermore, people with experience abroad show higher levels of resilience. They are more active concerning problem solving and have higher abilities to maintain emotional distance to work. Additionally, people show the more cultural intelligence the longer they stay abroad. Regarding the manifestation of cultural intelligence, the contact quality with the host country nationals played a significant role. It was evinced that higher contact quality is associated with higher values of cultural intelligence. Regarding occupational performance capacity, the results highlight that participants with a stay abroad are more dominant in an occupational context, i.e., they are more oriented towards superiority above others. Value: The present study contributes to the understanding of relevant personal skills and characteristics in intercultural contexts and of how personality might affect the process of becoming more competent. By demonstrating that stays abroad can increase certain work-related competences for students this study indicates that companies and educational institutions should spend more recourses on fostering experiences abroad of students and workers, in order to stay in tune with the requirements of globalization.
Apprendre aux étudiants paramédicaux à collaborer : dynamique et continuum de pratiques collaboratives dans un dispositif de formation
Authors: Boujard Servane , Le Faou Yann , Guirimand Nicolas 
Published: October 2020

L’évolution des besoins en santé nécessite, pour une population donnée, d’améliorer la collaboration entre les différents professionnels des domaines sanitaire et médico-social. Cela demande de repenser les formations initiales en santé pour permettre aux jeunes professionnels de s’adapter à ces nouvelles pratiques de terrain. C’est pourquoi, l’Institut de Formation en Pédicurie-podologie, Ergothérapie et Kinésithérapie (IFPEK) de Rennes a mis en place un dispositif de formation à la collaboration interprofessionnelle. La présente recherche analyse l’effet de ce dispositif sur la professionnalité émergente de 181 étudiants pédicure-podologues, ergothérapeutes et kinésithérapeutes, notamment dans leur capacité à mettre en place des interactions interprofessionnelles dans le cadre d’un travail collaboratif. Dix entretiens semi-directifs auprès de ces étudiants ainsi que des observations directes lors de la formation ont été menés. En s’appuyant sur le modèle canadien du « Continuum des pratiques de collaboration en santé et service sociaux », les résultats montrent qu’une grande majorité des étudiants s’orientent spontanément vers des pratiques collaboratives mais que leurs interactions sont parfois insuffisantes pour répondre aux problématiques de santé les plus complexes.
Jede Büchersammlung ein Werk für sich?
Authors: Hermes-Wladarsch Maria 
Published: October 2020

Zusammenfassung
Der Beitrag beleuchtet anhand von vier Projekten aus der Staats- und Universitätsbibliothek Bremen Wege und Charakteristika bibliothekarischer Provenienzrecherche. Vorgestellt werden: 1. Die Sammlung des Polyhistors und Bücherliebhabers Melchior Goldast von Haiminsfeld, 2. Provenienzrecherchen im Kontext von NS-Raubgut; 3. Sogenanntes kriegsbedingt verlagertes Kulturgut und 4. Das Digitalisierungsprojekt Digitale Sammlung Deutscher Kolonialismus.
Dimensionality reduction for EEG-based sleep stage detection: comparison of autoencoders, principal component analysis and factor analysis
Authors: Tăuţan Alexandra-Maria , Rossi Alessandro C. , de Francisco Ruben , Ionescu Bogdan 
Published: October 2020

Abstract
Methods developed for automatic sleep stage detection make use of large amounts of data in the form of polysomnographic (PSG) recordings to build predictive models. In this study, we investigate the effect of several dimensionality reduction techniques, i.e., principal component analysis (PCA), factor analysis (FA), and autoencoders (AE) on common classifiers, e.g., random forests (RF), multilayer perceptron (MLP), long-short term memory (LSTM) networks, for automated sleep stage detection. Experimental testing is carried out on the MGH Dataset provided in the “You Snooze, You Win: The PhysioNet/Computing in Cardiology Challenge 2018”. The signals used as input are the six available (EEG) electoencephalographic channels and combinations with the other PSG signals provided: ECG – electrocardiogram, EMG – electromyogram, respiration based signals – respiratory efforts and airflow. We observe that a similar or improved accuracy is obtained in most cases when using all dimensionality reduction techniques, which is a promising result as it allows to reduce the computational load while maintaining performance and in some cases also improves the accuracy of automated sleep stage detection. In our study, using autoencoders for dimensionality reduction maintains the performance of the model, while using PCA and FA the accuracy of the models is in most cases improved.
Zwischen Putin und Trump:Orbáns illiberale Demokratie und das Spektakel des Sports in Ostmitteleuropa
Authors: Kalmar Ivan 
Published: October 2020

ZusammenfassungWie schaffen es illiberale Politiker, mit einer Politik gewählt zu werden, die gegen die Interessen ihrer Wähler verstößt? Eine mögliche Antwort ist, dass sie Spektakel als Ersatz für Debatten und politische Auseinandersetzung bieten. Mit den Arbeiten von Roland Barthes zu Mythologie und von Guy Debords zu Spektakeln argumentiere ich, dass für illiberale Führungsspitzen wie Putin, Trump und Orbán das Spektakel des Sports dazu dient, die Debattenkultur in der praktischen Politik zu übertünchen. Orbáns Variante dieser Spektakel ist von besonderem Interesse für den europäischen Kontext, da sie aufzeigt, wie die illiberale Beseitigung einer Debattenkultur innerhalb der Regelwerke und Vorgaben der Europäischen Union möglich wird.
Analysis of pore throat characteristics of tight sandstone reservoirs
Authors: Zhao Xinli , Yang Zhengming , Liu Xuewei , Wang Zhiyuan , Luo Yutian 
Published: October 2020

Abstract
The characterization of pore throat structure in tight reservoirs is the basis for the effective development of tight oil. In order to effectively characterize the pore -throat structure of tight sandstone in E Basin, China, this study used high-pressure mercury intrusion (HPMI) testing technology and thin section (TS) technology to jointly explore the characteristics of tight oil pore throat structure. The results of the TS test show that there are many types of pores in the tight sandstone, mainly the primary intergranular pores, dissolved pores, and microfractures. Based on the pore throat parameters obtained by HPMI experiments, the pore throat radius of tight sandstone is between 0.0035 and 2.6158 µm. There are two peaks in the pore throat distribution curve, indicating that the tight sandstone contains at least two types of pores. This is consistent with the results of the TS experiments. In addition, based on the fractal theory and obtained capillary pressure curve by HPMI experiments, the fractal characteristics of tight sandstone pore throat are quantitatively characterized. The results show that the tight sandstones in E Basin have piecewise fractal (multifractal) features. The segmentation fractal feature occurs at a pore throat radius of approximately 0.06 µm. Therefore, according to the fractal characteristics, the tight sandstone pore throat of the study block is divided into macropores (pore throat radius > 0.06 µm) and micropores (pore throat radius < 0.06 µm). The fractal dimension D
L of the macropores is larger than the fractal dimension D
S of the micropores, indicating that the surface of the macropores is rough and the pores are irregular. This study cannot only provide certain support for characterizing the size of tight oil pore throat, but also plays an inspiring role in understanding the tight pore structure of tight sandstone.
Effects of igneous intrusions on source rock in the early diagenetic stage: A case study on Beipiao Formation in Jinyang Basin, Northeast China
Authors: Sun Shouliang , Zhang Tao , Li Yongfei , Chen Shuwang , Sun Qiushi 
Published: October 2020

Abstract
Mesozoic intrusive bodies play an important role in the temperature history and hydrocarbon maturation of the Jinyang Basin in northeastern China. The Beipiao Formation, which is the main source rock in Jinyang Basin, was intruded by numerous igneous bodies and dykes in many areas. The effects of igneous intrusive bodies on thermal evolution and hydrocarbon generation and migration in the Beipiao Formation were investigated. A series of samples from the outcrop near the intrusive body were analyzed for vitrinite reflectance (R
0%) and other organic geochemical parameters to evaluate the lateral extension of the thermal aureole. The R
0 values of the samples increase from a background value of ∼0.9% at a distance above 200 m from the intrusive body to more than 2.0% at the vicinity of the contact zone. The width of the altered zone is equal to the thickness of the intrusive body outcropped in the field. Organic geochemical proxies also indicate the intrusive body plays a positive and beneficial role in the formation of regional oil and gas resources. Due to the influence of the anomalous heat from the intrusive body, the hydrocarbon conversion rate of the source rocks of the Beipiao Formation was significantly improved. The accumulation properties and the storage capacity of the shales also greatly improved due to the intrusive body as indicated by the free hydrocarbon migration in the shales. This new understanding not only provides a reliable scientific basis for the accurate assessment of oil and gas genesis and resources in the Jinyang Basin but also provides guidance and reference for oil and gas exploration in the similar type of basin.
Optimization of heat treatment of glass-ceramics made from blast furnace slag
Authors: Wang Yi-Ci , Liu Pei-Jun , Luo Guo-Ping , Liu Zhe , Cao Peng-Fei 
Published: October 2020

AbstractCaO–MgO–Al2O3–SiO2 glass-ceramics with diopside as the main crystalline phase were prepared by melting blast furnace slag obtained from Baotou Iron and Steel Company. The effect of heat treatment on the crystallization behavior of glass-ceramics, containing a large proportion of melted blast furnace slag, was studied by means of differential thermal analysis and scanning electron microscopy. The optimum heat-treatment regime was obtained by orthogonal experimental results for glass-ceramics in which blast furnace slag comprised 70% of the composition and 1% Cr2O3 and 4% TiO2 were used as nucleating agents. The nucleation temperature was 750°C for 2.5 h and the crystallization temperature was 930°C for 1 h. Under this regime, the performance of the glass-ceramic was better than that of other groups in the orthogonal experiment.