bluuebunny/crossref_metadata_2025_split huggingface dataset:
Catalytic Semi‐Water–Gas Shift Reaction: A Simple Green Path to Formic Acid Fuel
Authors: Qadir Muhammad I. , Castegnaro Marcus V. , Selau Felipe F. , Samperi Mario , Fernandes Jesum Alves , Morais Jonder , Dupont Jairton 
Published: February 2020

AbstractFormic acid (FA) is a promising CO and hydrogen energy carrier, and currently its generation is mainly centered on the hydrogenation of CO2. However, it can also be obtained by the hydrothermal conversion of CO with H2O at very high pressures (>100 bar) and temperatures (>200 °C), which requires days to complete. Herein, it is demonstrated that by using a nano‐Ru/Fe alloy embedded in an ionic liquid (IL)‐hybrid silica in the presence of the appropriate IL in water, CO can be catalytically converted into free FA (0.73 m) under very mild reactions conditions (10 bar at 80 °C) with a turnover number of up to 1269. The catalyst was prepared by simple reduction/decomposition of Ru and Fe complexes in the IL, and it was then embedded into an IL‐hybrid silica {1‐n‐butyl‐3‐(3‐trimethoxysilylpropyl)‐imidazolium cations associated with hydrophilic (acetate, SILP‐OAc) and hydrophobic [bis((trifluoromethyl)sulfonyl)amide, SILP‐NTf2] anions}. The location of the alloy nanoparticles on the support is strongly related to the nature of the anion, that is, in the case of hydrophilic SILP‐OAc, RuFe nanoparticles are more exposed to the support surface than in the case of the hydrophobic SILP‐NTf2, as determined by Rutherford backscattering spectrometry. This catalytic membrane in the presence of H2O/CO and an appropriate IL, namely, 1,2‐dimethyl‐3‐n‐butylimidazolium 2‐methyl imidazolate (BMMIm⋅MeIm), is stable and recyclable for at least five runs, yielding a total of 4.34 mof free FA.
Modeling and analysis of LC filter integrated quasi‐Z source indirect matrix converter
Authors: Guo Mingzhu , Liu Yushan , Ge Baoming , Liu Shuo , Li Xiao , Ferreira Fernando J.T.E. , de Almeida Anibal T. 
Published: February 2020

SummaryThe existing model of LC filter integrated quasi‐Z source indirect matrix converter (QZS‐IMC) was derived using the DC circuit modeling method, which is mainly effective in DC circuit. As an ac circuit, the existing voltage boost ratio model of LC filter integrated QZS‐IMC exhibits a big error from the real boost ratio. Moreover, current amplitude and phase angle of QZS network were not considered in the existing model. This paper proposes a new comprehensive model of LC filter integrated QZS‐IMC taking into account the circuit's ac characteristics. The new model shows that voltage boost ratio is strongly related to QZS network inductance, capacitance, and frequency of input power supply. It can be concluded from the new model that the boost ratio is higher than 1/(1 − 2D), which is the boost ratio of existing model. Moreover, the new model shows that power factor affects voltage gain of QZS‐IMC system. The new model is compared with the existing model, circuit simulation, and experimental test. The results verify the new model and analysis.
Malignant effusions from extranodal NK/T‐cell lymphomas are frequently of anaplastic morphology with azurophilic granules and of T‐cell lineage
Authors: Liu Chih‐Yi , Chen Bo‐Jung , Chuang Shih‐Sung ,   Taiwan Hematopathology Study Group
Published: February 2020

AbstractBackgroundExtranodal natural killer/T‐cell lymphoma (ENKTL) nasal type is an extranodal lymphoma, with most cases arising from the prototypic nasal/upper aerodigestive tract and the cell of origin (COO) is frequently of NK cells. Effusion involvement by ENKTL is rare. The cytomorphological and immunophenotypical features and COO of effusion ENKTL are elusive.DesignWe report four new cases of effusion ENKTL, reviewing the cytomorphological features and investigating their COO by immunohistochemistry for T‐cell receptor (TCR) protein expression and clonality assay for TCR gene rearrangement. We also reviewed 12 additional cases of effusion ENKTL from the literature.ResultsAll our four cases showed anaplastic tumor cells with fine to coarse azurophilic granules, with the primary tumor organs from the prototypic sites (2), small intestine (1), or indeterminate (1). The COO was either T‐cell (3) or NK‐cell (1). Compiling our four cases with that from the literature, all 16 effusion ENKTL cases were Epstein‐Barr virus‐associated and the majority (83%; 10/12) originated from the nonprototypic sites. Five of six (83%) effusion ENKTL cases were of T‐cell lineage. Prognosis was poor with a median survival time of only 2.4 months.ConclusionsOur study revealed that ENKTL in the effusion might be characterized by anaplastic large cell morphology, cytoplasmic azurophilic granules, and a higher proportion of T‐cell lineage as compared to de novo tumors arising from the prototypic sites. ENKTL rarely presented in effusion, which is associated with dismal outcome. Large international studies are warranted to validate these findings.
Gray plumage color is more cryptic than brown in snowy landscapes in a resident color polymorphic bird
Authors: Koskenpato Katja , Lehikoinen Aleksi , Lindstedt Carita , Karell Patrik 
Published: February 2020

AbstractCamouflage may promote fitness of given phenotypes in different environments. The tawny owl (Strix aluco) is a color polymorphic species with a gray and brown morph resident in the Western Palearctic. A strong selection pressure against the brown morph during snowy and cold winters has been documented earlier, but the selection mechanisms remain unresolved. Here, we hypothesize that selection favors the gray morph because it is better camouflaged against predators and mobbers in snowy conditions compared to the brown one. We conducted an online citizen science experiment where volunteers were asked to locate a gray or a brown tawny owl specimen from pictures taken in snowy and snowless landscapes. Our results show that the gray morph in snowy landscapes is the hardest to detect whereas the brown morph in snowy landscapes is the easiest to detect. With an avian vision model, we show that, similar to human perceivers, the brown morph is more conspicuous than the gray against coniferous tree trunks for a mobbing passerine. We suggest that with better camouflage, the gray morph may avoid mobbers and predators more efficiently than the brown morph and thus survive better in snowy environments. As winters are getting milder and shorter in the species range, the selection periods against brown coloration may eventually disappear or shift poleward.
Steep topography buffers threatened gymnosperm species against anthropogenic pressures in China
Authors: Jensen Ditte Arp , Ma Keping , Svenning Jens‐Christian 
Published: February 2020

AbstractChina is one of the most species‐rich countries in the world, harboring many rare gymnosperms. Following recent human‐led loss of forests, China is now experiencing increases in forest cover resulting from efforts of reforestation schemes. As anthropogenic activities have previously been found to interact with topography in shaping forest cover in China and considering the large human population and the ongoing population increase of the country, it is important to understand the role of anthropogenic pressures relative to environmental drivers for shaping species distributions here. Based on the well‐established relationship between human population density and topography, we propose a hypothesis for explaining species distributions in a country dominated by human activities, predicting that species are more likely to occur in areas of steep topography under medium human population densities compared to low and high human population densities. Using species occurrence data from the Chinese Vascular Plant Distribution Database along with a common SDM method (maximum entropy modeling), we tested this hypothesis. Our results show that steep topography has the highest importance for predicting Chinese gymnosperm species occurrences in general, and threatened species specifically, in areas of medium human population densities. Consequently, these species are more often found in areas of steep terrain, supporting the proposed hypothesis. Results from this study highlight the need to include topographically heterogeneous habitats when planning new protected areas for species conservation.
Sex‐specific floral attraction traits in a sequentially hermaphroditic species
Authors: Peach Kristen , Liu Jasen W. , Klitgaard Kristen N. , Mazer Susan J. 
Published: February 2020

Abstract

Many angiosperms are hermaphroditic and produce bisexual flowers in which male (pollen export) and female (stigma receptivity) functions are separated temporally. This sequential hermaphroditism may be associated with variation in flower size, color, or pattern, all of which may influence pollinator attraction. In this study, we describe variation in these traits across discrete functional sex stages within and between 225 greenhouse‐grown individuals of Clarkia unguiculata (Onagraceae). In addition, to identify the effects of floral phenotype on pollinator attraction in this species, we examine the effects of these floral traits on pollen receipt in ~180 individuals in an experimental field array.

Petal area, ultraviolet (UV)‐absorbing nectar guide area, and blue and green mean petal reflectance differ significantly across the functional sex stages of C. unguiculata. Male‐ and female‐phase flowers display significantly different pollinator attraction traits. Petal and UV nectar guide area increase as flowers progress from male phase to female phase, while blue reflectance and green reflectance peak during anther maturation.

In field arrays of C. unguiculata, female‐phase flowers with large UV nectar guides receive more pollen than those with small nectar guides, and female‐phase flowers with high mean blue reflectance values are more likely to receive pollen than those with low blue reflectance. Female‐phase flowers with green mean reflectance values that differ most from background foliage also receive more pollen than those that are more similar to foliage. These findings indicate that components of flower color and pattern influence pollen receipt, independent of other plant attributes that may covary with floral traits. We discuss these results in the context of hypotheses that have been proposed to explain sex‐specific floral attraction traits, and we suggest future research that could improve our understanding of sexual dimorphism in sequentially hermaphroditic species and the evolution of features that promote outcrossing.
Specialization of plant–pollinator interactions increases with temperature at Mt. Kilimanjaro
Authors: Classen Alice , Eardley Connal D. , Hemp Andreas , Peters Marcell K. , Peters Ralph S. , Ssymank Axel , Steffan‐Dewenter Ingolf 
Published: February 2020

AbstractAimSpecies differ in their degree of specialization when interacting with other species, with significant consequences for the function and robustness of ecosystems. In order to better estimate such consequences, we need to improve our understanding of the spatial patterns and drivers of specialization in interaction networks.MethodsHere, we used the extensive environmental gradient of Mt. Kilimanjaro (Tanzania, East Africa) to study patterns and drivers of specialization, and robustness of plant–pollinator interactions against simulated species extinction with standardized sampling methods. We studied specialization, network robustness and other network indices of 67 quantitative plant–pollinator networks consisting of 268 observational hours and 4,380 plant–pollinator interactions along a 3.4 km elevational gradient. Using path analysis, we tested whether resource availability, pollinator richness, visitation rates, temperature, and/or area explain average specialization in pollinator communities. We further linked pollinator specialization to different pollinator taxa, and species traits, that is, proboscis length, body size, and species elevational ranges.ResultsWe found that specialization decreased with increasing elevation at different levels of biological organization. Among all variables, mean annual temperature was the best predictor of average specialization in pollinator communities. Specialization differed between pollinator taxa, but was not related to pollinator traits. Network robustness against simulated species extinctions of both plants and pollinators was lowest in the most specialized interaction networks, that is, in the lowlands.ConclusionsOur study uncovers patterns in plant–pollinator specialization along elevational gradients. Mean annual temperature was closely linked to pollinator specialization. Energetic constraints, caused by short activity timeframes in cold highlands, may force ectothermic species to broaden their dietary spectrum. Alternatively or in addition, accelerated evolutionary rates might facilitate the establishment of specialization under warm climates. Despite the mechanisms behind the patterns have yet to be fully resolved, our data suggest that temperature shifts in the course of climate change may destabilize pollination networks by affecting network architecture.
Simplified Compact Perovskite Solar Cells with Efficiency of 19.6% via Interface Engineering
Authors: Li Dedi , Liu Changwen , Chen Shi , Kong Weiguang , Zhang Haichao , Wang Deng , Li Yan , Chang Jianhui , Cheng Chun 
Published: February 2020

For the commercialization of perovskite solar cells (PSCs), it is more appealing to develop high‐performance simplified PSCs where perovskite films are just sandwiched between the back and front electrodes, in order to simplify the fabrication process and to reduce the cost. However, to date, this kind of devices shows rather low performance, and there are few researches on this subject. Herein, we report on a kind of compact PSCs (CPSCs) that are free of independent charge transport layers (CTLs). The devices are realized by the use of organic monolayer‐modified effective electrodes, along with the use of [6,6]‐phenyl‐C61‐butyric acid methyl ester (PCBM)‐assisted anti‐solvent technique to obtain ultra‐thin (~10 nm) PCBM‐embedded perovskite films. Compared to control devices, CPSCs achieve a promising champion power conversion efficiency of 19.6% with largely reduced hysteresis. Moreover, the unencapsulated CPSC shows good stability under ambient atmosphere, with only 10% efficiency loss after 60 days’ storage. This work indicates that, by delicate design, CPSCs with smaller materials consumption in device architecture can perform competitively as conventional PSCs. Further reduction in the actual usage of costly CTL materials can be expected upon our CPSCs by developing more facile and economic methods to prepare ultra‐thin CTLs.
Effectiveness of sacubitril–valsartan in cancer patients with heart failure
Authors: Martín‐Garcia Ana , López‐Fernández Teresa , Mitroi Cristina , Chaparro‐Muñoz Marinela , Moliner Pedro , Martin‐Garcia Agustin C. , Martinez‐Monzonis Amparo , Castro Antonio , Lopez‐Sendon Jose L. , Sanchez Pedro L. 
Published: February 2020

AbstractAimsCurrent guidelines recommend sacubitril/valsartan for patients with heart failure and reduced left ventricular ejection fraction (LVEF), but there is lack of evidence of its efficacy and safety in cancer therapy‐related cardiac dysfunction (CTRCD). Our aim was to analyse the potential benefit of sacubitril/valsartan in patients with CTRCD.Methods and resultsWe performed a retrospective multicentre registry (HF‐COH) in six Spanish hospitals with cardio‐oncology clinics including all patients treated with sacubitril/valsartan. Demographic and clinical characteristics and laboratory and echocardiographic data were collected. Median follow‐up was 4.6 [1; 11] months. Sixty‐seven patients were included (median age was 63 ± 14 years; 64% were female, 87% had at least one cardiovascular risk factor). Median time from anti‐cancer therapy to CTRD was 41 [10; 141] months. Breast cancer (45%) and lymphoma (39%) were the most frequent neoplasm, 31% had metastatic disease, and all patients were treated with combination antitumor therapy (70% with anthracyclines). Thirty‐nine per cent of patients had received thoracic radiotherapy. Baseline median LVEF was 33 [27; 37], and 21% had atrial fibrillation. Eighty‐five per cent were on beta‐blocker therapy and 76% on mineralocorticoid receptor antagonists; 90% of the patients were symptomatic NYHA functional class ≥II. Maximal sacubitril/valsartan titration dose was achieved in 8% of patients (50 mg b.i.d.: 60%; 100 mg b.i.d.: 32%). Sacubitril/valsartan was discontinued in four patients (6%). Baseline N‐terminal pro‐B‐type natriuretic peptide levels (1552 pg/mL [692; 3624] vs. 776 [339; 1458]), functional class (2.2 ± 0.6 vs. 1.6 ± 0.6), and LVEF (33% [27; 37] vs. 42 [35; 50]) improved at the end of follow‐up (all P values ≤0.01). No significant statistical differences were found in creatinine (0.9 mg/dL [0.7; 1.1] vs. 0.9 [0.7; 1.1]; P = 0.055) or potassium serum levels (4.5 mg/dL [4.1; 4.8] vs. 4.5 [4.2; 4.8]; P = 0.5). Clinical, echocardiographic, and biochemical improvements were found regardless of the achieved sacubitril–valsartan dose (low or medium/high doses).ConclusionsOur experience suggests that sacubitril/valsartan is well tolerated and improves echocardiographic functional and structural parameters, N‐terminal pro‐B‐type natriuretic peptide levels, and symptomatic status in patients with CTRCD.
Ischaemic cardiomyopathy. Pathophysiological insights, diagnostic management and the roles of revascularisation and device treatment. Gaps and dilemmas in the era of advanced technology
Authors: Cabac‐Pogorevici Irina , Muk Balazs , Rustamova Yasmin , Kalogeropoulos Andreas , Tzeis Stylianos , Vardas Panos 
Published: February 2020

AbstractIschaemic cardiomyopathy (ICM) represents an important cardiovascular condition associated with substantially increased morbidity and mortality. It is characterised from a broad spectrum of clinical manifestations and pathophysiological substrates and its diagnosis is based on the demonstration of significant left ventricular dysfunction in the context of significant epicardial coronary artery disease. Contemporary management aims at improving prognosis through evidence‐based pharmacotherapy and device therapy, where indicated. Whilst the beneficial role of revascularisation remains clear in patients with strong indications such as those with symptoms and/or acute coronary syndromes, for those patients that are asymptomatic and suffer from stable ischaemic heart disease the impact of revascularisation on hard outcomes remains less well defined and currently its adoption is hampered by the lack of robust randomised data. The aim of this review is therefore to provide a constructive appraisal on the pathophysiology of ICM, the role of the various non‐invasive imaging techniques in the diagnosis of ICM and the differentiation between viable and non‐viable myocardium and finally discourse the potential role of revascularisation and contemporary device therapy in the management of patients with ICM.
Scale‐down simulators for mammalian cell culture as tools to access the impact of inhomogeneities occurring in large‐scale bioreactors
Authors: Paul Katrin , Herwig Christoph 
Published: February 2020

AbstractDuring the scale‐up of a bioprocess, not all characteristics of the process can be kept constant throughout the different scales. This typically results in increased mixing times with increasing reactor volumes. The poor mixing leads in turn to the formation of concentration gradients throughout the reactor and exposes cells to varying external conditions based on their location in the bioreactor. This can affect process performance and complicate process scale‐up. Scale‐down simulators, which aim at replicating the large‐scale environment, expose the cells to changing environmental conditions. This has the potential to reveal adaptation mechanisms, which cells are using to adjust to rapidly fluctuating environmental conditions and can identify possible root causes for difficulties maintaining similar process performance at different scales. This understanding is of utmost importance in process validation. Additionally, these simulators also have the potential to be used for selecting cells, which are most robust when encountering changing extracellular conditions. The aim of this review is to summarize recent work in this interesting and promising area with the focus on mammalian bioprocesses, since microbial processes have been extensively reviewed.
Applications of online integrated system for coal and gas outburst prediction: A case study of Xinjing Mine in Shanxi, China
Authors: Zhao Xusheng , Sun Haitao , Cao Jie , Ning Xiaoliang , Liu Yanbao 
Published: February 2020

AbstractIn this study, an indicator model and system for coal and gas outburst prediction are identified and established based on gas geological anomalies, mining stress, and gas emission characteristics. In this regard, the coal and gas outburst prevention techniques and mine rules in China are taken into account. In addition, using this model, an online integrated system and database for coal and gas outburst prediction were built for Xinjing Mine in Shanxi Province. The application results of the prediction system indicate that the system software and hardware can guarantee early warning of coal and gas outburst. The system is continuous and stable, and the early warning results are issued in a timely and accurate manner. The accuracy of the early warning results is high and consistent with the actual risk of the mine.
Quantification of contemporary storm‐induced boulder transport on an intertidal shore platform using radio frequency identification technology
Authors: Hastewell Linley , Inkpen Robert , Bray Malcolm , Schaefer Martin 
Published: February 2020

AbstractExtreme storm events are known to produce, entrain, transport and deposit sizable boulders along rocky coastlines. However, the extent to which these processes occur under moderate, fetch‐limited wave conditions is seldom considered. In this study we quantify boulder transport at a relatively sheltered location subject to high‐frequency, low‐magnitude storm activity. This was achieved by deploying radio frequency identification (RFID) tags within 104 intertidal limestone boulders ranging in size from fine to very coarse (intermediate axis: 0.27–2.85 m). The study was conducted over 3 years (July 2015–July 2018) and encompassed numerous storm events. Tagged boulders were relocated during 17 field surveys and their positions recorded using a differential global positioning navigation satellite system (DGNSS).On completion, we identified boulder displacement in 69% of the tagged array. The accrued boulder transport distance amounted to 233.0 m from 195 incidents of displacement, including the movement of a boulder weighing an estimated 11.9 t. Transport was not confined to autumn and winter storms alone, as displacement was also recorded during summer months (April–September), despite the seasonally reduced wave magnitude.Boulder production by wave quarrying was documented in three tagged clasts, confirming observations that the shore platform is actively eroding. Incidents of overturning during transport were also recorded, including multiple overturning of clasts weighing up to 5 t. We further identify a statistically significant difference (maximum p‐value ≤ 0.03) between the transport distances attributed to constrained and unconstrained boulders, suggesting that the pre‐transport morphological setting exerts considerable control over boulder transport potential.The findings establish low to moderate storm waves as a key component in the evolution of the study site. More broadly, we claim that high‐frequency, low‐magnitude storms regularly modify these overlooked rocky coastal locations, suggesting that the hydrodynamic capability at such sites may previously have been underestimated. © 2020 John Wiley & Sons, Ltd.