bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relevance of the use of electroencephalography and audiometry for the diagnosis of drug-related nervous system complications in patients with multi-drug resistant pulmonary tuberculosis during the main course of chemotherapy
Authors: Ignatieva V.I. , Martsinyuk T.M. , Svyatnenko V.A. , Gumeniuk G.L. 
Published: September 2020

PURPOSE. To analyze the relevance of introduction of modern diagnostics methods for the evaluation of drug-related complications that affect the nervous system in TB treatment practice.
MATERIALS AND METHODS. We have analyzed the literature data regarding the problem of diagnosing drug-related complications that affect the nervous system in patients with multi-drug resistant pulmonary tuberculosis during the main course of chemotherapy.
RESULTS. According to the results of the analysis, it was revealed that today in the TB practice there is over- or under-diagnosing of drug-related complications from the part of nervous system in patients with multi-drug resistant pulmonary tuberculosis during the main course of chemotherapy, which is due to the lack of technical possibilities of control and the need to get conclusions from specialists with narrow expertise – otolaryngologists, ophthalmologists and neuropathologists.
CONCLUSIONS. The lack of data on the prevalence of drug-related nervous system complications is due to the possibility of their detection only with the help of specific technical means of control and on the basis of the conclusions of narrow specialists. The wide introduction of electroencephalography using evoked potentials and audiometry in TB practice will allow obtaining objective data on prevalence, carrying out clear differential diagnostics, monitoring the development of such complications, as well as providing timely treatment within the required amount.
Short-term physical and chemical stability of mixtures of anti-tuberculosis drugs for intravenous administration
Authors: Kuzhko M.M. , Tlustova T.M. , Denysov O.S. , Sprynsian T.A. , Shukha Yu.V. 
Published: September 2020

PURPOSE. To evaluate the stability of mixtures of anti-tuberculosis drugs for intravenous administration used for treatment of sensitive and resistant tuberculosis in time and in conditions close to the conditions of the use.
MATERIALS AND METHODS. Studied combinations: ethambutol + isoniazid in various concentrations, ethambutol + levofloxacin, ethambutol + moxifloxacin. In the stability study, samples were taken for analysis of the appearance, pH and concentration of drugs at specified times (immediately after mixing, after 16, and 24 hours).
RESULTS. The results of the chromatographic study indicate the absence of chemical interaction between the active pharmaceutical ingredients, high physical and chemical stability of the mixtures for up to 24 hours of storage under conditions close to the conditions of use, except the mixture of isoniazid with ethambutol, in which it is recommended to reduce the storage term to 16 hours due to the complexity of interpretation and the nature of potential impurities.
CONCLUSIONS. Study results indicate the possibility of simultaneous administration of a mixture of isoniazid and ethambutol when the preparation of the mixture was not more than 16 hours prior to administration and mixtures of ethambutol + levofloxacin and ethambutol + moxifloxacin with the preparation of the mixture no more than 24 hours before administration.
WÜRTTEMBERŠKI GORSKI BATALJON IN
12. SOŠKA OFENZIVA
Authors: TORKAR BLAŽ , KUHAR MIHA 
Published: September 2020

Povzetek
Württemberški gorski bataljon je bil nemška vojaška enota dežele Württemberg. Oblikovan je bil precej pozno, šele oktobra 1915. Enota, ki ji je poveljeval major Theodor Sprösser, je prevzela pomembno vlogo v 12. soški ofenzivi, saj je ves čas delovala v konici napada alpskega korpusa in pozneje 1. avstro-ogrskega korpusa Krauss. Pomembno vlogo znotraj bataljona je imel tudi nadporočnik Erwin Rommel, ki je skupaj z majorjem Sprösserjem prejel visoko odlikovanje pour le mérite za uspešne boje ob reki Soči v prvih dneh ofenzive in operacijo Longarone. Bataljon je ves čas prodora od Tolmina do reke Piave deloval decentralizirano na več samostojnih smereh, saj so njegovi častniki razumeli in obvladali načelo poveljevanja s poslanstvom (Auftragstaktik) ter obvladali veščine nove taktike prodora. Bataljon je bil decembra 1917 skupaj z drugimi enotami 14. armade premeščen z italijanske fronte na opravljanje nove bojne naloge.

Ključne besede: prva svetovna vojna, soška fronta, 12. soška ofenziva, Württemberški gorski bataljon, Theodor Sprösser, Erwin Rommel.

Abstract
The Württemberg Mountain Battalion was a German military unit on the territory of Württemberg. It was formed relatively late, only in October 1915. The unit, which was commanded by Major Theodor Sprösser assumed a very important role in the Twelfth Isonzo Offensive. It was continuously engaged in the peak of the attack by the Alpine Corps’ (Alpenkorps) and later 1st Austro-Hungarian corps Krauss. An important role within the battalion was also played by First Lieutenant Erwin Rommel, who was together with Major Sprösser awarded a decoration “pour la mérite” for his success in the battles near the Isonzo River in the first days of the offensive, and for the Longarone operation. Throughout the penetration from Tolmino to the Piava River, the battalion functioned in a decentralised manner on several independent routes, since the commanders understood and mastered the mission command (Auftragstaktik) and mastered the skills of the new penetration tactics. In December 1917, the battalion and other units of the 14th Army were redeployed from the Italian front to a new combat assignment.

Key words: First World War, Isonzo Front, Twelfth Isonzo Offensive, Württemberg Mountain Battalion, Theodor Sprösser, Erwin Rommel.
Regulação da saúde no Brasil: conceitos, governança e acesso.
Authors: Bastos Luzia Beatriz Rodrigues , Barbosa Maria Alves , Bastos Diniz Antonio de Sena 
Published: September 2020

O estudo visa compreender os conceitos de regulação em saúde, governança e regulação do acesso, í luz das produções cientí­ficas nacionais de 2006 a 2018. Pautou-se em revisão sistemática realizada a partir dos termos regulação, saúde, governança e acesso, nos Descritores em Ciências da Saúde, que resultaram na identificação de 73 artigos, sendo 20 selecionados para o estudo. Após análise criteriosa, foram elaboradas 3 categorias: conceitos de regulação em saúde, com 4 artigos (20%); governança na regulação, 5 artigos (25%), e regulação do acesso ou assistencial, 11 artigos (55%). A regulação está assentada principalmente na quantidade adequada de ações e serviços de saúde disponí­veis í população e na qualidade dos padrões dos serviços ofertados. Há necessidade de regulação, em razão dos tetos financeiros disponibilizados í saúde e às contradições, em relação aos marcos regulatórios instituí­dos por municí­pios e estados. Novos estudos precisam ser elaborados na ótica da regulação do acesso e nas novas formas de governança do Estado regulador que grande parte das vezes, transfere responsabilidades para a prestação dos serviços de saúde a entidades prestadoras, imprimindo formas mais brandas de regulação.Palavras-chave: regulação e fiscalização em saúde, governança, acesso aos serviços de saúde, Sistema Único de Saúde.
Exploring adipogenic and myogenic circulatory biomarkers of recurrent pressure injury risk for persons with spinal cord injury
Authors: Bogie Kath M , Schwartz Katelyn , Li Youjin , Wang Shengxuan , Dai Wei , Sun Jiayang 
Published: September 2020

Purpose: To investigate linkages between circulatory adipogenic and myogenic biomarkers, gluteal intramuscular adipose tissue (IMAT), and pressure injury (PrI) history following spinal cord injury (SCI).
Methods: This is an observational repeated-measures study of 30 individuals with SCI. Whole blood was collected regularly over 2-3 years. Circulatory adipogenic and myogenic gene expression was determined. IMAT was defined as above/below 15% (IMATd) or percentage (IMAT%). PrI history was defined as recurrent PrI (RPrI) or PrI number (nPrI). Model development used R packages (version 3.5.1). Univariate analysis screened for discriminating genes for downstream multivariate and combined models of averaged and longitudinal data for binary (RPrI/IMATd) and finer scales (nPrI/IMAT%).
Results: For adipogenesis, Krüppel-like factor 4 was the top RPrI predictor together with resistin and cyclin D1, and sirtuin 2 was the top IMAT predictor. For myogenesis, the top RPrI predictor was dysferlin 2B, and pyruvate dehydrogenase kinase-4 was the top IMAT predictor together with dystrophin.
Conclusion: Circulatory adipogenic and myogenic biomarkers have statistically significant relationships with PrI history and IMAT for persons with SCI. Biomarkers of interest may act synergistically or additively. Variable importance rankings can reveal nonlinear correlations among the predictors. Biomarkers of interest may act synergistically or additively, thus multiple genes may need to be included for prediction with finer distinction.
A importância da utilização do cateter central de inserção periférica
Authors: Gomes Rayla Oliveira , Lima Thiago Oliveira Sabino , Silva Raylton Aparecido Nascimento , Abreu Vitor Pachelle Lima , Silva Robson Mariano Oliveira , Silva Fabrício Ferreira , Santos Jessica Costa Moreira dos , Ferreira Ruhena Kelber Abrão 
Published: September 2020

O cateter venoso central de inserção periférica PICC é um cateter que se insere em uma veia periférica e progride para veia cava superior ou inferior adquirindo características de um cateter central. É um dispositivo que possui diversas versões, com um, dois ou três lumens, é flexível, radiopaco, de paredes lisas e homogêneas, feito de silicone ou poliuretano. Tal dispositivo beneficia no tratamento ao neonato que requer cuidados prolongados. O presente estudo visa analisar a importância da utilização do Cateter Central de Inserção Periférica – PICC no cuidado a neonatos enfermos, bem como analisar a função da equipe de enfermagem na inserção e manutenção dessa técnica. A metodologia utilizada foi pesquisa bibliográfica com análise de artigos científicos, teses e outras publicações de enfermagem encontrados em bases de dados relacionadas com o tema. Os resultados encontrados a partir dos estudos revisados mostraram que PICC é um dispositivo advindo das novas tecnologias que proporcionam um melhor tratamento aos recém-nascidos que precisam de tratamento prolongado. O enfermeiro e a equipe de enfermagem devem sempre está se atualizando e capacitando para prestar um atendimento humanizado e de qualidade.
Abordagem cirúrgica de pilomatricoma – relato de caso
Authors: Cavalcante Mateus Barros , Rodrigues Éwerton Daniel Rocha , Uchôa Caio Pimenteira , Silva Joana de Ângelis Alves , Rocha Caroline Brigida Sá , Torres Luiz Henrique Soares , Silva Emanuel Dias de Oliveira e 
Published: September 2020

Pilomatricoma ou epitelioma calcificante de Malherbe é uma neoplasia cutânea benigna rara, com origem nas células da matriz do folículo piloso que surge na maioria dos casos durante a infância ou adolescência. Clinicamente apresentam-se frequentemente como nódulos assintomáticos, com coloração geralmente semelhante à pele normal, localizados predominantemente na cabeça, pescoço ou extremidades superiores, de consistência habitualmente dura, crescimento lento e na maioria dos casos solitárias. A excisão cirúrgica é geralmente recomendada para os pilomatricomas, para prevenir o seu crescimento ou comprometimento estético, não havendo recidiva como regra. O presente relato tem por objetivo a apresentação de um caso de pilomatricoma e sua abordagem cirúrgica intra-oral, bem como discutir a literatura pertinente sobre o tema. O relato de caso descreve paciente com queixa de nódulo na bochecha. O anatomopatológico diagnosticou pilomatricoma. Após a cirurgia, a paciente evoluiu sem complicações, sendo acompanhada ambulatorialmente. Por apresentar extensas possibilidades de diagnóstico diferencial o diagnóstico clínico isolado se torna difícil. Sendo assim, é importante que o profissional esteja familiarizado com essa neoplasia.
Um conto de fadas nos 5 reinos dos seres vivos: ensinando ciências na alfabetização
Authors: Silva Aline da , Deccache-Maia Eline 
Published: September 2020

A relação ciência e arte no ensino tem enorme potencial historicamente evidenciado produzindo resultados interessantes, como os aqui apresentados. Nossas atividades, voltadas ao ensino de ciências, centraram-se na temática dos cinco reinos dos seres vivos em uma turma do 1º ano do Ensino Fundamental I, aliando perspectivas construtivista, da aprendizagem significativa e da ludicidade. O foco interdisciplinar auxiliou na elaboração de uma história em quadrinhos, permitindo verificar como ocorreram a assimilação do tema, a promoção da alfabetização propriamente dita e a científica. A metodologia de ensino foi realizada em etapas e o seu acompanhamento feito por meio da pesquisa qualitativa pela observação participante. O tema proposto contribuiu surpreendentemente para as aulas, pois as crianças sentiram-se contempladas pelas atividades interdisciplinares, podendo ser observado que a inclusão de temas científicos desde cedo, respeitando as especificidades da faixa etária dos alunos, não onerou o seu desenvolvimento, ao contrário, colaborou para o seu incremento.
Elaboração e caracterização de produto farináceo a partir da folha do umbuzeiro (Spondias tuberosa Arruda)
Authors: Ferreira Sânzia Viviane de Farias , Campos Ana Regina Nascimento , Medeiros Maria Franco Trindade 
Published: September 2020

O objetivo do trabalho foi à elaboração e caracterização física e química de um produto farináceo produzido a partir das folhas do umbuzeiro (Spondias tuberosa Arruda) utilizando diferentes métodos de secagem. Os procedimentos experimentais consistiram em produção de farinhas a partir da secagem de 30 g de folhas em estufa de circulação de ar à 60 °C por 6 h e em forno micro-ondas (FMO) com potência de 100% em ciclo único de 2 min e 30 s. Os parâmetros físicos e químicos avaliados tanto nas folhas in natura, quanto nas farinhas elaboradas foram: teor de água (TA), atividade de água, pH, sólidos solúveis totais (SST), proteína bruta (PB), resíduo mineral fixo (RMF) e quantificação de minerais. O valor médio de TA da folha do umbuzeiro in natura (75,06%) foi superior ao encontrado nas farinhas, que apresentaram valores próximos entre si, em torno de 6,00%, bem como os valores de atividade de água, sendo para as folhas in natura (0,987), farinha em estufa (0,330) e farinha em FMO (0,323). As farinhas analisadas apresentaram ainda, pH ácido, valores de SST de 7,17 °Brix (estufa) e 10,27 °Brix (FMO), percentual de PB de 9,00% (estufa) e 8,60% (FMO). Além de valores de RMF (acima de 12,00%) indicando elevado teor mineral, com destaque para o Ca, K, Mg, Fe, Zn e Cu. O processo de secagem mostrou-se viável, produzindo farinhas com valores de TA dentro das normas vigentes e rendimentos semelhantes para os dois métodos de secagem empregados (23,0%).
Features of a Hybrid of Common Guinea Fowl and Rooster of Orpington Breed
MAU "Yaroslavl Zoo"
Authors: Сырчина Е.А. , Скворцова Е.Г. 
Published: September 2020

Исследованы и сопоставлены размеры и экстерьерные признаки гибридной особи цесарка обыкновенная × петух орпингтон и родительских особей, содержащихся в МАУ «Ярославский зоопарк». Исследования проводились с помощью взятия промеров птиц измерительной лентой и фотофиксации их отличительных признаков. В результате исследования размеров птиц установлено, что гибридная особь имеет большие размеры, чем цесарка обыкновенная, но меньшие, чем петух породы орпингтон, при этом обладает большей длиной шеи и ног, чем родительские особи. При исследовании экстерьерных признаков установлено, что гибридная особь обладает уникальной окраской (белая с бежевыми и серыми вкраплениями), а также полным отсутствием наростов на голове, которые характерны для родительских особей. Остальные признаки гибрида имеют общие черты с родительскими особями.
The sizes and exterior features of the hybrid individual of the common guinea fowl × Orpington rooster and parental animals keeping in the Yaroslavl Zoo MAU were investigated and compared. Researches were carried out by taking measurements of birds with yard-measure and photofixing their distinctive features. As a result of a study of the size of birds it was found that the hybrid individual has larger sizes than the common guinea fowl but smaller than the rooster of Orpington breed while having a larger neck and leg length than the parental animals. When studying the exterior features it was found that the hybrid individual has a unique color (white interspersed with beige and gray) as well as the complete absence of growths on the head which are characteristic of parental animals. The remaining features of the hybrid have common features with parental animals.
Da Forza Italia e Alleanza Nazionale al Popolo della Libertà, e ritorno: dinamiche territoriali e contraddizioni politiche
Authors: Pritoni Andrea 
Published: September 2020

Less than fi ve years after its formal establishment, the National Council of PDL – which met on 11-16-2013 at the ‘Palazzo dei Congressi’ in Rome – decided for the dissolution of the party and the subsequent confl ence of all its members and leaders in a new political entity which was called again Forza Italia. A party that – in the first two years of its political life – had proven to be a powerful tool with respect to various majoritarian electoral disputes, was definitively dismissed without any regret. Aside from the considerations linked to the gradual weakening of Silvio Berlusconi’s leadership, which is certainly a major issue, this article examines the impact of territorial dynamics – in particular, intra-party competition and party territorial roots – on the electoral results obtained by PDL in the 2013 Italian parliamentary elections. Unlike what argued
for a long time, these dynamics have much affected those electoral results. Although the largest Italian center-right party still remains inextricably tied to the fluctuating fortunes of its founding leader (Silvio Berlusconi), in the future the so-called ‘moderate coalition’
Le sette elezioni federali nella Germania unita (1990-2013)
Authors: Caciagli Mario 
Published: September 2020

Stability and predictability had been the norm in the German political system before the unification. The seven federal elections in the unified Germany from 1990 to 2013 did have significant consequences on the traditional continuity. After the last two governments headed by Helmut Kohl (1990-1998), the Social Democrat Gerhard Schröder became Chancellor in a Red-Green coalition (1998-2005) and the Christian Democrat Angela Merkel became Chancellor, fi rst in a Grand Coalition with the Social Democrats (2005-2009), than in a coalition with the Liberals (2009-2013), and after the 2013 elections in a Grand Coalition again. These frequent changes can be explained by the mobility of the electorate: the cumulative effect of the growth of the middle class and the general social mobility have eroded traditional loyalties, as the disaffection of the youth includes changing electoral choices or tendency to no-vote. Economic and social issues too did have effect on voting behavior: because their critical social situation the electors of the East had preferred fi rst Kohl’s CDU, than Schröder’s SPD and again the CDU under Merkel’s leadership; in the West millions of left electors disappointed by Schröder’s contentious reforms of the labor market leaved the SPD in the 2009 and 2013 elections; the performance of the economy in the last years after periods of crisis, collocating Germany at the top of the European Union, has stimulated the support to Merkel. Because a new party, the PDS than Linke, which has stable roots in the East, but can’t be partner of a government; because the exclusion from the Bundestag of the liberal FDP; and, finally, because the least reform of the electoral system toward more proportionality: all that injects uncertainty into a “fluid” party and political system.
PENGARUH METODE LATIHAN AGILITY HURDLE DRILL DAN AGILITY LEADER TERHADAP KOORDINASI KAKI ANGGOTA UKM FUTSAL UNIVERSITAS MUSAMUS MERAUKE
Authors: Sumarsono Adi 
Published: September 2020

Abstrak: Penelitian ini bertujuan untuk: 1) Mengetahui pengaruh metode latihan agility hurdle drill terhadap koordinasi kaki pada anggota UKM Futsal Universitas Musamus. 2) Mengetahui pengaruh metode latihan agility leader terhadap koordinasi kaki pada anggota UKM Futsal Universitas Musamus. 3) Mengetahui perbedaan pengaruh metode latihan agility hurdle drill dan metode latihan agility leader terhadap koordinasi kaki serta untuk mengetahui manakah yang lebih efektif untuk meningkatkan koordinasi kaki pada anggota UKM Futsal Universitas Musamus. Penelitian ini merupakan penelitian eksperimen dengan menggunakan desain penelitian two group pretest-postest design. Instrumen dalam penelitian ini menggunakan tes soccer wall volley test dari Ismaryanti. Teknik analisis data menggunakan uji prasarat yaitu uji normalitas dan uji homogenitas, sedangkan uji hipotesis menggunakan uji t. Hasil penelitian menunjukkan bahwa 1) ada pengaruh penggunaan metode latihan agility hurdle drill terhadap koordinasi kaki anggota UKM Futsal Universitas Musamus. 2) Ada pengaruh penggunaan metode latihan agility leader terhadap koordinasi kaki anggota UKM Futsal Universitas Musamus. 3) Terdapat perbedaan yang signifikan antara pengaruh metode latihan agility hurdle drill dengan metode latihan agility leader terhadap koordinasi kaki pada anggota UKM Futsal Universitas Musamus. Metode latihan agility leader lebih efektif dari pada metode latihan agility hurdle drill terhadap koordinasi kaki pada anggota UKM Futsal Universitas Musamus. Hal itu dibuktikan dengan diperolehnya data peningkatan metode agility leader memiliki mean sebesar 2,54, dan peningkatan metode latihan agility hurdle drill memiliki mean sebesar 1,23, atau (2,54 ? 1,23). Kata Kunci: hurdle drill, agility leader dan koordinasi kaki.
PENGARUH METODE LATIHAN SIRKUIT DAN METODE KONVENSIONAL TERHADAP KETERAMPILAN DASAR BOLA BASKET
Authors: Perdima Feby Elra 
Published: September 2020

Abstrak: Berdasarkan pengamatan penulis di lapangan menunjukkan bahwa masih kurangnya keterampilan dasar bolabasket SMA Negeri 1 Lebong Utara. Penelitian ini bertujuan untuk menjelaskan perbedaan pengaruh metode Latihan Sirkuit dengan metode Konvensional terhadap peningkatan keterampilan dasar bolabasket SMA Negeri 1 Lebong Utara. Metode penelitian ini adalah metode eksperimen semu (quasi eksperimental). Populasi penelitian ini sejumlah 32 orang siswa, sampel diambil mengunakan teknik sampling jenuh sehingga diperoleh sampel sebanyak 32 orang siswa. Tes yang digunakan adalah tes dribble zig-zag, passing dan under basket yang bertujuan untuk mengetahui keterampilan dasar bolabasket SMA Negeri 1 Lebong Utara. Teknik analisis data yang digunakan adalah uji-t. Hasil analisis data menunjukan bahwa: (1) Metode Latihan Sirkuit dapat meningkatkan keterampilan dasar bolabasket SMA Negeri 1 Lebong Utara (thitung 16,77 > ttabel ?=0,051,75) (2) Metode konvensional dapat meningkatkan keterampilan dasar bolabasket SMA Negeri 1 Lebong Utara (thitung 9,25> ttabel ?=0,05 1,75) (3) Terdapat perbedaan yang berarti antara Metode latihan Sirkuit dengan Metode Konvensional terhadap keterampilan dasar bolabasket SMA Negeri 1 Lebong Utara (thitung 1,35 <ttabel ?=0,0 1,75). Kata kunci: Metode Latihan Sirkut, Metode Konvensional, Keterampilan Dasar Bola Basket