bluuebunny/crossref_metadata_2025_split huggingface dataset:
Moringa oleifera seed oil partially abrogates 2,3-dichlorovinyl dimethyl phosphate (Dichlorvos)-induced cardiac injury in rats: evidence for the role of oxidative stress
Authors: Saka Waid A. , Ayoade Titilayo E. , Akhigbe Tunmise M. , Akhigbe Roland E. 
Published: November 2020

Abstract

Objectives
Cardiovascular diseases are major causes of non-infectious diseases globally. The use of pesticides has been linked with the high global burden of non-communicable diseases. Despite the indiscriminate exposure to dichlorvos (DDVP) by inhalation, no report exists on its possible cardiotoxic effect. This study investigated the cardiotoxicity of DDVP exposure by inhalation and the possible role of Moringa oleifera seed oil.

Methods
Twenty-one male rats were randomly assigned into 3 groups. Group A (control) received only standard rat diet and water ad’ libitum, group B (DDVP) was exposed to DDVP via inhalation for 15 min daily in addition to rat diet and water, and group C (DDVP + M. oleifera seed oil) received treatment as group B as well as 300 mg/kg of M. oleifera seed oil p.o for 28 days.

Results
Significant reductions in body weight gain and cardiac weight were observed in DDVP-exposed animals (p<0.05). Similarly, 28 days of exposure to DDVP led to a significant increase in lactate dehydrogenase, creatinine kinase and troponin (p<0.05). DDVP-exposed rats also showed a significant increase in malondialdehyde, and a significant decline in superoxide dismutase and glutathione peroxidase (p<0.05). However, catalase was comparable in DDVP-exposed and control rats. Histopathological observations of the cardiac tissue revealed that DDVP caused marked fat degeneration and necrosis of the myocardial layer. The changes in DDVP-exposed rats were significantly, though not completely, restored by M. oleifera seed oil administration.

Conclusions
This study provides novel mechanistic information on the cardiotoxicity of DDVP inhalation, and the antioxidant potential of M. oleifera seed oil.
Industrialisierung oder Kapitalismus: Alternative Zentralbegriffe
Authors: Kocka Jürgen 
Published: November 2020

Abstract
For decades, industrialization has served as the most important key concept for structuring comprehensive and specialized studies in the field of 19th and 20th century social and economic history of many countries. How do the dominant views change if, instead, capitalism is used as the structuring key concept? Both concepts are products of the 19th century. They address similar aspects of reality and can be used for synthetical purposes. They can be used in studies with different spatial dimensions: from micro to global scales. They can be combined. But they differ as to the time spans they cover, the temporal perspectives they stress, and the way in which they combine analytical and critical functions. Recently we observe a dramatic re-emergence of the concept capitalism.
Das Wechselkreditgeschäft der Reichsbank vor der Bankenkrise von 1931
Authors: Burhop Carsten 
Published: November 2020

Abstract
This article examines two aspects of the Reichsbank’s discount business in the years 1924 to 1932: First, the granting of Reichsbank discount loans to commercial banks in their function as lenders of last resort. Second, the direct granting of discount loans by the Reichsbank to non-banks to finance the short-term assets of industry and trade. From 1931 onwards, the Reichsbank increasingly granted financial discount loans to alleviate the liquidity crisis of the commercial banks. I trace this in detail for the Reichsbank branch in Leipzig. With regard to the granting of loans by the Reichsbank to trade and industry, I find indications of relatively high credit risks in the Reichsbank’s portfolio, especially in the granting of small loans. The extensive efforts in loan selection and loan monitoring documented here could not remedy the situation.
Management of labor after external cephalic version
Authors: Levin Gabriel , Rottenstreich Amihai , Meyer Raanan , Weill Yishay , Pollack Raphael N. 
Published: November 2020

Abstract

Objectives
Current literature evaluating the role of induction of labor (IOL) following successful external cephalic version (ECV) attempt as compared to expectant management is limited. We aim to assess the risk of cesarean delivery in those undergoing immediate IOL following successful ECV as compared to those who were expectantly managed.

Methods
A retrospective cohort study of successful external cephalic versions. The study group included 57 women that were induced after procedure in the lack of maternal or fetal indications for induction of labor. These women were compared to 341 expectantly managed women. Maternal and fetal characteristics and outcomes were compared.

Results
Gestation age at delivery was higher among the expectant management group (401/7 vs. 384/7, median, p=0.002) as compared to the induction group. Cesarean delivery rates were similar between both groups (28 [8.2%] vs. 3 [5.3%], p=0.44). In a multivariate logistic regression analysis, only nulliparity was significantly associated with cesarean delivery (adjusted odds ratio 3.42, confidence interval 1.61–7.24, p=0.001). No correlation was found between the version-to-delivery interval and the risk for cesarean delivery.

Conclusions
Induction of labor after successful ECV was not shown to influence cesarean delivery rates. As immediate IOL may result in higher rate of early-term deliveries, and in light of the lack of clinical benefit, we advocate against elective IOL following successful ECV.
COVID-19 in pregnancy: creating an outpatient surveillance model in a public hospital system
Authors: Trostle Megan E. , Silverstein Jenna S. , Tubridy Elizabeth , Limaye Meghana A. , Rose Jessica , Brubaker Sara G. , Chervenak Judith L. , Denny Colleen C. 
Published: November 2020

Abstract

Objectives
We describe a standardized, scalable outpatient surveillance model for pregnant women with COVID-19 with several objectives: (1) to identify and track known, presumed, and suspected COVID-positive pregnant patients both during their acute illness and after recovery, (2) to regularly assess patient symptoms and escalate care for those with worsening disease while reducing unnecessary hospital exposure for others, (3) to educate affected patients on warning symptoms, hygiene, and quarantine recommendations, and (4) to cohort patient care, isolating stable infected patients at home and later within the same physical clinic area upon their return to prenatal care.

Methods
Pregnant women in an urban public hospital system with presumed or confirmed COVID-19 were added to a list in our electronic medical record as they came to the attention of providers. They received a series of phone calls based on their illness severity and were periodically assessed until deemed stable.

Results
A total of 83 patients were followed between March 19 and May 31, 2020. Seven (8%) were asymptomatic, 62 (75%) had mild disease, 11 (13%) had severe disease, and three (4%) had critical illness.

Conclusions
We encourage others to develop and utilize outpatient surveillance systems to facilitate appropriate care and to optimize maternal and fetal well-being.
Alexander the Great’s Route to Gaugamela and Arbela
Authors: Marciak Michal , Sobiech Marcin , Pirowski Tomasz 
Published: November 2020

SummaryThe aim of this paper is to analyse the chronology and itinerary of the march of the Macedonian army during the last days (September 18–October 1) of the Gaugamela campaign in 331 BC in the light of literary sources, cuneiform data, topographic and archaeological data, and GIS capabilities. The overall aim of this analysis is to contribute to the topographical enigma of the identification of Gaugamela as either (in the vicinity of) Tell Gomel or Karamleis/Qaraqosh. The cuneiform data allows us to establish the most important dates of the final course of the Gaugamela campaign: the Tigris crossing on September 18, a lunar eclipse on the evening of September 20, and the battle on October 1. Furthermore, a critical analysis of Arrian and Curtius suggests that the Macedonians spent only six days on the march and four days in the camp. Given the estimated average rate of the march of the Macedonian army, it is possible to reject certain routes between the Tigris crossing and Gaugamela and consider others as more or less likely. It is concluded that the Macedonians crossed the Tigris in the vicinity of modern Basorin and not Abu Dhahir or Abu Wajnam, as is widely assumed. Furthermore, it is also demonstrated that the difference between Tell Gomel and Karamleis/Qaraqosh, regarding their distance from Arbela, is much less striking than is frequently assumed, and as such does not speak against any of the widely held identifications of Gaugamela.
Robust superabsorbent p(MAPTAC) hydrogels with long physical cross-link junctions: synthesis, characterization and their performance for phosphate removal from wastewater
Authors: Aydınoğlu Demet 
Published: November 2020

Abstract
Ionic hydrogels with great water absorption capacity generally display poor mechanical strength that limits their use and narrows down their application areas. In this study, the new ionic hydrogel composed of poly (3-methacrylamido propyl trimethyl ammonium chloride) crosslinked with N, N-methylenebisacrylamide and sulphate ions was synthesized to obtain the hydrogel formulation which exhibits both huge swelling capacity and high mechanical stability, simultaneously. The successively synthesized gels with this strategy achieved a swelling capacity of 270 g/g and a modulus increased up to 20.43 kPa, indicating that they have a great potential to use in applications in which the both properties are required. The gels carrying a great number of cationic sites were also found to have a high affinity to phosphate ions, attaining an sorption value of 370 mg/g gel and to exhibit pseudo-second-order kinetic and Langmuir sorption isotherm models. The obtained results revealed that the new pMAPTAC gels have good potential for both phosphate sorption and high water uptake capacity without losing structural integrity owing to their enhanced mechanical strength.
Genetic parkinsonisms and cancer: a systematic review and meta-analysis
Authors: Sturchio Andrea , Dwivedi Alok K. , Vizcarra Joaquin A. , Chirra Martina , Keeling Elizabeth G. , Mata Ignacio F. , Kauffman Marcelo A. , Pandey Manoj K. , Roviello Giandomenico , Comi Cristoforo , Versino Maurizio , Marsili Luca , Espay Alberto J. 
Published: November 2020

Abstract
Genes associated with parkinsonism may also be implicated in carcinogenesis, but their interplay remains unclear. We systematically reviewed studies (PubMed 1967–2019) reporting gene variants associated with both parkinsonism and cancer. Somatic variants were examined in cancer samples, whereas germline variants were examined in cancer patients with both symptomatic and asymptomatic (carriers) genetic parkinsonisms. Pooled proportions were calculated with random-effects meta-analyses. Out of 9,967 eligible articles, 60 were included. Of the 28 genetic variants associated with parkinsonism, six were also associated with cancer. In cancer samples, SNCA was predominantly associated with gastrointestinal cancers, UCHL1 with breast cancer, and PRKN with head-and-neck cancers. In asymptomatic carriers, LRRK2 was predominantly associated with gastrointestinal and prostate cancers, PRKN with prostate and genitourinary tract cancers, GBA with sarcoma, and 22q11.2 deletion with leukemia. In symptomatic genetic parkinsonism, LRRK2 was associated with nonmelanoma skin cancers and breast cancers, and PRKN with head-and-neck cancers. Cancer was more often manifested in genetic parkinsonisms compared to asymptomatic carriers. These results suggest that intraindividual genetic contributions may modify the co-occurrence of cancer and neurodegeneration.
Trace dynamics and division algebras: towards quantum gravity and unification
Authors: Singh Tejinder P. 
Published: November 2020

Abstract
We have recently proposed a Lagrangian in trace dynamics at the Planck scale, for unification of gravitation, Yang–Mills fields, and fermions. Dynamical variables are described by odd-grade (fermionic) and even-grade (bosonic) Grassmann matrices. Evolution takes place in Connes time. At energies much lower than Planck scale, trace dynamics reduces to quantum field theory. In the present paper, we explain that the correct understanding of spin requires us to formulate the theory in 8-D octonionic space. The automorphisms of the octonion algebra, which belong to the smallest exceptional Lie group G
2, replace space-time diffeomorphisms and internal gauge transformations, bringing them under a common unified fold. Building on earlier work by other researchers on division algebras, we propose the Lorentz-weak unification at the Planck scale, the symmetry group being the stabiliser group of the quaternions inside the octonions. This is one of the two maximal sub-groups of G
2, the other one being SU(3), the element preserver group of octonions. This latter group, coupled with U(1)
em
, describes the electrocolour symmetry, as shown earlier by Furey. We predict a new massless spin one boson (the ‘Lorentz’ boson) which should be looked for in experiments. Our Lagrangian correctly describes three fermion generations, through three copies of the group G
2, embedded in the exceptional Lie group F
4. This is the unification group for the four fundamental interactions, and it also happens to be the automorphism group of the exceptional Jordan algebra. Gravitation is shown to be an emergent classical phenomenon. Although at the Planck scale, there is present a quantised version of the Lorentz symmetry, mediated by the Lorentz boson, we argue that at sub-Planck scales, the self-adjoint part of the octonionic trace dynamics bears a relationship with string theory in 11 dimensions.
Spontaneous Network Coupling Enables Efficient Task Performance without Local Task-Induced Activations
Authors: Allaman Leslie , Mottaz Anaïs , Kleinschmidt Andreas , Guggisberg Adrian G. 
Published: November 2020

Neurobehavioral studies in humans have long concentrated on changes in local activity levels during repetitive executions of a task. Spontaneous neural coupling within extended networks has latterly been found to also influence performance. Here, we intend to uncover the underlying mechanisms, the relative importance, and the interaction between spontaneous coupling and task-induced activations. To do so, we recorded two groups of healthy participants (male and female) during rest and while they performed either a visual perception or a motor sequence task. We demonstrate that, for both tasks, stronger activations during the task as well as greater network coupling through spontaneous α rhythms at rest predict performance. However, high performers present an absence of classical task-induced activations and, instead, stronger spontaneous network coupling. Activations were thus a compensation mechanism needed only in subjects with lower spontaneous network interactions. This challenges classical models of neural processing and calls for new strategies in attempts to train and enhance performance.SIGNIFICANCE STATEMENTOur findings challenge the widely accepted notion that task-induced activations are of paramount importance for behavior. This will have an important impact on interpretations of human neurobehavioral research. They further link the widely used techniques of quantifying network communication in the brain with classical neuroscience methods and demonstrate possible ways of how network communication influences human behavior. Traditional training methods attempt to enhance neural activations through task repetitions. Our findings suggest a more efficient neural target for learning: enhancing spontaneous neural interactions. This will be of major interest for a large variety of scientific fields with very broad applications in schools, work, and others.
JAMAICAN CRIME AND ECONOMY
Authors: YAZGAN HADZIBULIC Seda 
Published: November 2020

This research paper examines an overview of literature on the most recent issues that are allied to crime and violence in Jamaica. They have been an issue which has affected the Caribbean as a whole but due to the islands many social and economic problems, it has shown an increase in crime and violence most noticeably in Jamaica. This issue has caused millions of people to live in fear due to the constant and never-ending crime and violence. The horrors of violence and crime has undoubtedly had a more profound and significant negative impact on the young population. My research will focus on the aspects of violence and crime in Jamaica. This paper will also cover the general conditions in Jamaica, the organized crime and the conventional violence, and how the impact of the crime has had an effect on economic growth. My conclusion will focus on the policies which these countries have to change that will significantly reduce crime and violence and as a result will provide a better social and economic future for all of its citizens. The aim of this research is to have a broader understanding about crime and violence in Jamaica and to raise global awareness about their conditions and the humanitarian problems.
Jel Codes: A13, E71
Health Impact Assessment and City Council Policy: Identifying Opportunities to Address Local Social Determinants of Health & Place-Health Relationships, 10 Years Later
Authors: Petteway Ryan , Cosgrove Shannon 
Published: November 2020

Background: Health Impact Assessment (HIA) can be used to assess any type of policy/program related to social determinants (SDH). However, local public health departments (LHDs) have been slow to adopt formal use of HIA in efforts to address local SDH, even with growing evidence linking SDH and place-health relationships. Ten years ago we completed a review of Baltimore City Council policies to advance this conversation within the LHD. Our goal here is to revisit this review and, again, outline a process by which LHDs can: a) monitor local policies in regard to SDH and b) identify opportunities for potential HIA use.
Methods: We reviewed all policies introduced into Baltimore City Council in calendar years 2008 and 2009. We reviewed each policy to identify those with potential health impacts. We then categorized these policies as: a) “explicitly health-related” or b) “related to SDH.” We then tabulated the number and sub-types of these policies that were referred for LHD review.
Results: We identified and reviewed 597 total policies. 89 policies (15%) were identified as “explicitly health-related,” 34 (38%) of which were referred for LHD review. 208 policies (35%) were identified as “related to SDH,” 13 (6%) of which were reviewed. Overall, 297 (50%) policies were identified as having potential health impacts, 47 (16%) of which were reviewed.
Conclusion: This work represents a potentially replicable process to identify HIA opportunities, and potential launch point for health-in-all-policies efforts. In Baltimore, it facilitated dialogue with Baltimore City officials and led to the LHD’s first HIA grant.
The Influence of Chronotype and Grit on Lifestyle and Physical Activity
Authors: Allee Melody F. , Anderson Sarah E. , Bloom Myra J. , Jost Scarlet R. , Keating III Donald P. , Lang Andrew S.I.D. , Mankin Nancy V. , Mast Zachary W. , Nelson Philip P. , Spear Esther M. , Valderrama Enrique F. 
Published: November 2020

Background: The chronotype of a person refers to an individual's natural sleep-wake cycle and whether that individual prefers morning or evening activities, and grit is an individual's perseverance and passion for long-term goals.Aim: The purpose of this study was to investigate the relationship between grit, chronotype, physical activity, and leading a healthy lifestyle in college-age students.Methods: Health and fitness data (i.e., chronotype, grit, lifestyle assessment score, and daily steps) from 431 first-semester university students at a private college were collected and analyzed. Results: This study found that grit and chronotype both have significant correlations with living a healthy lifestyle and with physical activity. Grit more accurately predicts a person's lifestyle (β = -13.712, r = 0.39, p < 0.0001) while chronotype more accurately predicts the physical activity, or steps, of a person (β = 66.48, r = .19, p = .0001). Chronotype can also accurately predict the grit of a person (r = .25, p < .0001), and it was found that morning people tend to have more grit.Conclusions: This study concluded that grit, chronotype, steps, and a healthy lifestyle are all significantly correlated with each other. Knowing the relationship between endogenous chronotype, grit, and living a physically active and healthy lifestyle can help inform policy decisions related to the goal of strengthening an institution's inclusive and healthy academic community.
Diagnostic and Prognostic Markers of Chronic Heart Failure in Patients with Occupational Chronic Obstructive Pulmonary Disease
Authors: Shpagina L. A. , Kamneva N. V. , Kudelya L. M. , Kotova O. S. , Shpagin I. S. , Kuznetsova G. V. , Anikina E. V. , Gerasimenko D. A. , Saraskina L. E. , Surovenko T. N. , Ponomareva A. V. 
Published: November 2020

Aim Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are a common comorbidity. Professional chronic obstructive pulmonary disease (PCOPD) is a specific phenotype, which suggests peculiarities in the development of HF. Difficulties of HF diagnosis in such patients determine the relevance of searching for additional markers. The aim of the study was identifying HF markers in patients with PCOPD.Material and methods This single-site, cohort, prospective, observational study included 345 patients. The main group consisted of PCOPD patients; the comparison group consisted of patients with COPD induced by tobacco smoking; and the control group included conventionally healthy individuals. The groups were matched by the index of coincidence; pairs were matched at 1:1 by the “nearest neighbor index”; covariates for matching included COPD duration, sex, and age. Each group included 115 patients. The major professional adverse factors were silica-containing dust and organic solvents. COPD was diagnosed according to GOLD criteria; HF was diagnosed in accordance with Russian clinical guidelines. The markers were determined by multifactorial logistic regression. Likelihood of events with allowance for the time to the event was analyzed by the Kaplan-Meier method.Results HF in PCOPD patients was characterized by biventricular damage, preserved left ventricular ejection fraction, and frequent hospitalizations for decompensation (17.5 % vs. 9.5 % for COPD in smokers). HF markers in patients with PCOPD included the length of work of more than 20 years, pulmonary artery systolic pressure (PASP) higher than 35 mm Hg according to data of Doppler echocardiography, diffusing capacity of lungs for carbon monoxide (DLCO) less than 50 %, increased serum concentrations of CC-chemokine ligand 18 (CCL18), S-100‑beta protein, and N-terminal pro-brain natriuretic peptide (NT-pro-BNP). Diagnostic sensitivity of the multifactorial model was 84 % and specificity was 81 %. Two models were proposed for purposes of screening, which included the following parameters: length of work, exposure to aromatic hydrocarbons, decreased distance in 6-min walk test by more than 60 m per year and length of work, exposure to inorganic dust, and decreased forced expiratory volume during the first second by more than 55 ml per year.Conclusion The markers for development of HF in PCOPD patients are length of work >20 years, PASP >35 mm Hg, DLCO <50 %, and increased serum concentrations of CCL18, S-100‑beta protein, and NT-pro-BNP.