bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of partial loss of hippocampal striation at 1.5 Tesla magnetic resonance imaging
Authors: Sen Anitha , Sankaran Sudhakaran 
Published: October 2019

Abstract

Objectives
Partial loss of hippocampal striation (PLHS) is recently described in 3 T and 7 T MR imaging as a sensitive indicator of hippocampal sclerosis. Primary objective: We described the demographic characteristics of the population with seizure disorder having PLHS at 1.5 T MR imaging and tried to see the relation of PLHS to the classic signs of hippocampal sclerosis. Secondary objective: PLHS was also looked for in a small control population that had no seizure history.

Methods
This retrospective study had the approval of the institutional review board. In patients demonstrating PLHS on oblique coronal T2-weighted images, the following were recorded: age, sex, EEG findings, side of PLHS, hippocampal atrophy and high signal intensity of the hippocampus. In control population, the following were recorded: age, sex, presence/absence of PLHS and indication for imaging.

Results
The 116 PLHS subjects (age range 2–73 years) included 62 males and 54 females. Sixty-six (56.9%) of our PLHS subjects were less than 18 years of age: 44 (37.9%) under the age of 12 years and 22 (19%) of 12–18 years of age. Classic signs of hippocampal sclerosis were found in only 7 (6%) of the 116 subjects showing PLHS. All patients with classic signs showed PLHS on the same side. Of the control population (25 subjects, age range 3–76 years, 17 males and 8 females), one showed PLHS—he was a treated case of CNS lymphoma with gliotic changes, though there was no history of seizure.

Conclusion
PLHS is demonstrated at 1.5 T in both adult and paediatric population in this article and is much more common than the classic signs of hippocampal sclerosis (increased signal intensity and volume loss).
Ralstonia mannitolilytica sepsis: a case report
Authors: Owusu Michael , Acheampong Godfred , Annan Augustina , Marfo Kwadwo Sarfo , Osei Isaac , Amuasi John , Sarpong Nimako , Im Justin , Mogeni Ondari D. , Chiang Hsin-Ying , Kuo Chih-Horng , Jeon Hyon Jin , Panzner Ursula , Park Se Eun , Marks Florian , Owusu-Dabo Ellis , Adu-Sarkodie Yaw 
Published: October 2019

AbstractBackgroundRalstonia mannitolilyticais an emerging opportunistic pathogen that is associated with severe disease, including septic shock, meningitis, and renal transplant infections. Reports on this pathogen are limited, however, especially on the African continent.Case presentationA 2-year-old Akan child was presented to a hospital in the northeastern part of Ghana with a 1-week history of fever and chills. We identifiedRalstonia mannitolilyticain her blood culture using both conventional and 16S ribosomal deoxyribonucleic acid (rDNA) techniques. The patient’s condition improved clinically upon treatment with cefuroxime.ConclusionOur report highlights the potential ofRalstonia mannitolilyticato cause sepsis and thus emphasizes the need for improved laboratory diagnosis and evidence for use of appropriate antibiotics in rural settings of Africa, where presumptive treatment using antimicrobial agents is rife.
Existence of solutions for equations and inclusions of multiterm fractional q-integro-differential with nonseparated and initial boundary conditions
Authors: Samei Mohammad Esmael , Khalilzadeh Ranjbar Ghorban , Hedayati Vahid 
Published: October 2019

Abstract
The goal of this paper is to investigate existence of solutions for the multiterm nonlinear fractional q-integro-differential ${}^{c}D_{q}^{\alpha } u(t)$

D
q
α

c

u
(
t
)
in two modes equations and inclusions of order $\alpha\in(n -1, n]$
α
∈
(
n
−
1
,
n
]
, with non-separated boundary and initial boundary conditions where the natural number n is more than or equal to five. We consider a Carathéodory multivalued map and use Leray–Schauder and Covitz–Nadler famous fixed point theorems for finding solutions of the inclusion problems. Besides, we present results whenever the multifunctions are convex and nonconvex. Lastly, we give some examples illustrating the primary effects.
On weighted integrability of functions defined by trigonometric series with p-bounded variation coefficients
Authors: Szal Bogdan , Kubiak Maciej 
Published: October 2019

Abstract
In this paper we introduce new classes of p-bounded variation sequences and give a sufficient and necessary condition for weighted integrability of trigonometric series with coefficients belonging to these classes. This is a generalization of the results obtained by the first author [J. Inequal. Appl. 2010:1–19, 2010] and Dyachenko and Tikhonov [Stud. Math. 193(3):285–306, 2009].
Composite inertial subgradient extragradient methods for variational inequalities and fixed point problems
Authors: Ceng Lu-Chuan , Yuan Qing 
Published: October 2019

Abstract
In this paper, we introduce and investigate composite inertial gradient-based algorithms with a line-search process for solving a variational inequality problem (VIP) with a pseudomonotone and Lipschitz continuous mapping and a common fixed-point problem (CFPP) of finitely many nonexpansive mappings and a strictly pseudocontractive mapping in the framework infinite-dimensional Hilbert spaces. The proposed algorithms are based on an inertial subgradient–extragradient method with the line-search process, hybrid steepest-descent methods, viscosity approximation methods and Mann iteration methods. Under weak conditions, we prove strong convergence of the proposed algorithms to the element in the common solution set of the VIP and CFPP, which solves a certain hierarchical VIP defined on this common solution set.
Exact dynamical behavior for a dual Kaup–Boussinesq system by symmetry reduction and coupled trial equations method
Authors: Li Wen-He , Wang Yong 
Published: October 2019

AbstractWe propose a coupled trial equation method for a coupled differential equations system. Furthermore, according to the invariant property under the translation, we give the symmetry reduction of a dual Kaup–Boussinesq system, and then we use the proposed trial equation method to construct its exact solutions which describe its dynamical behavior. In particular, we get a cosine function solution with a constant propagation velocity, which shows an important periodic behavior of the system.
Stress among university students: factorial structure and measurement invariance of the Italian version of the Effort-Reward Imbalance student questionnaire
Authors: Portoghese Igor , Galletta Maura , Porru Fabio , Burdorf Alex , Sardo Salvatore , D’Aloja Ernesto , Finco Gabriele , Campagna Marcello 
Published: October 2019

Abstract

Background
In the last decade academic stress and its mental health implications amongst university students has become a global topic. The use of valid and theoretically-grounded measures of academic stress in university settings is crucial. The aim of this study was to examine the factorial structure, reliability and measurement invariance of the short student version of the effort-reward imbalance questionnaire (ERI-SQ).

Methods
A total of 6448 Italian university students participated in an online cross-sectional survey. The factorial structure was investigated using exploratory factor analysis and confirmatory factor analysis. Finally, the measurement invariance of the ERI-SQ was investigated.

Results
Results from explorative and confirmatory factor analyses showed acceptable fits for the Italian version of the ERI-SQ. A modified version of 12 items showed the best fit to the data confirming the 3-factor model. Moreover, multigroup analyses showed metric invariance across gender and university course (health vs other courses).

Conclusions
In sum, our results suggest that the ERI-SQ is a valid, reliable and robust instrument for the measurement of stress among Italian university students.
Large dependency of charge distribution in a tropical cyclone inner core upon aerosol number concentration
Authors: Sato Yousuke , Miyamoto Yoshiaki , Tomita Hirofumi 
Published: October 2019

Abstract
The impacts of aerosols on the charge distribution of hydrometeors and lightning flash density in a tropical cyclone (TC) were investigated using a meteorological model coupled with an explicit lightning model. The meteorological model successfully simulated the tripole structure of charge density distribution in a TC, as reported by previous studies. The impacts of aerosols were investigated through a sensitivity experiment with changing the aerosol number concentration. The tripole structure became unclear with increasing aerosol number concentrations. The positive charge distribution located in the lower layer was not seen, and raindrops with negative charge distribution reached the surface. As a result, the vertical structure of the charge density was dipolar in the polluted case. As the tripole structure shifted to dipole, the magnitude of the electric field tended to be large, and the flash number was large. By contrast, in the pristine case, the tripole structure was dominant, and the flash number was much smaller than in the polluted case.
Fungi as source for new bio-based materials: a patent review
Authors: Cerimi Kustrim , Akkaya Kerem Can , Pohl Carsten , Schmidt Bertram , Neubauer Peter 
Published: October 2019

Abstract

Background
The circular economy closes loops in industrial manufacturing processes and minimizes waste. A bio-based economy aims to replace fossil-based resources and processes by sustainable alternatives which exploits renewable biomass for the generation of products used in our daily live. A current trend in fungal biotechnology—the production of fungal-based biomaterials—will contribute to both.

Results
This study gives an overview of various trends and development applications in which fungal mycelium is used as new and sustainable biomaterial. A patent survey covering the last decade (2009–2018) yielded 47 patents and patent applications claiming fungal biomass or fungal composite materials for new applications in the packaging, textile, leather and automotive industries. Furthermore, fungal-based materials are envisaged for thermal insulation and as fire protection materials. Most patents and patent applications describe the use of different lignin- and cellulose-containing waste biomass as substrate for fungal cultivations, covering 27 different fungal species in total. Our search uncovered that most patent activities are on-going in the United States and in China.

Conclusion
Current patent developments in the field suggest that fungal bio-based materials will considerable shape the future of material sciences and material applications. Fungal materials can be considered as an excellent renewable and degradable material alternative with a high innovation potential and have the potential to replace current petroleum-based materials.
Total thymectomy for thymic lymphoepithelioma-like carcinoma—report of two cases
Authors: Kawagishi Sachi , Ose Naoko , Minami Masato , Funaki Soichiro , Kanou Takashi , Kimura Kenji , Taniguchi Seiji , Morii Eiichi , Shintani Yasushi 
Published: October 2019

Abstract

Background
Thymic carcinoma has been classified into 12 subtypes, thymic lymphoepithelioma-like carcinoma (LELC) is a type of them, and has a pathological organization similar to that of lymphoepithelioma, an undifferentiated type of nasopharyngeal carcinoma. According to a report from the International Thymic Malignancy Interest Group (ITMIG), thymic LELC is a rare tumor and accounts for 6% of all thymic carcinoma cases. We report two cases of surgical resection for thymic LELC and perform a search of other reports of thymic LELC, and clinical manifestations and follow-up data thus obtained are summarized.

Case presentation
Two patients underwent surgical resection for thymic LELC. In both, tumors were detected in the anterior mediastinum and a total thymectomy was performed. Each was diagnosed with thymic LELC and classified in accordance with the Masaoka staging system as modified stage II. In recent examinations, one patient was doing well after undergoing total resection, whereas early recurrence of distant lymph node metastasis was noted in the other at 5 months after the total resection procedure and died thereafter from a different disease.

Conclusion
We report two cases of surgical resection for thymic LELC. A successful total resection may positively affect prognosis: thus, long-term follow-up examinations must be performed.
Compulsory coding in education: liberal-humanism, Baudrillard and the ‘problem’ of abstraction
Authors: Tamatea Laurence 
Published: October 2019

AbstractInternationally, coding is increasingly introduced into primary and junior high schools (children generally aged between 5 and 15) on a compulsory basis, though not all stakeholders support this ‘initiative’. In response to the public reception, discussion highlights popular argument around compulsory coding in school education. This is an argument between those supportive (hereafter referred to as the Yes case) and those unsupportive of compulsory coding (hereafter referred to as the No case). But more than simply produce a list of arguments, this discussion contributes to our understanding of this reception by identifying the ‘discourses’ deployed by both cases (namely, digital ubiquity, disadvantage, and habits of mind discourses) and by providing theoretical framings through which these discourses and their potential implications might be differently understood. Using critical discourse analysis to unpack these discourses shows that while both cases hold to key tenets of liberal-humanism, a commitment to the individual subject, liberty and full participation in the social, it is the Yes case with its stronger commitment to children engaging in abstraction that seems to challenge these. Discussion of this difference is framed by the work of Baudrillard around abstraction, not to ‘prove’ the validity of Baudrillard’s thesis concerning the consequences of humanity’s deepening engagement with abstraction, but to provide a broader understanding of this debate, in relation to a trajectory of engagement with abstraction that seems set to intensify.
Evaluation of meaningful change in bowel movement frequency for patients with carcinoid syndrome
Authors: Hudgens Stacie , Ramage John , Kulke Matthew , Bergsland Emily , Anthony Lowell , Caplin Martyn , Öberg Kjell , Pavel Marianne , Gable Jonathon , Banks Phillip , Yang Qi Melissa , Lapuerta Pablo 
Published: October 2019

AbstractBackgroundCarcinoid syndrome is associated with a reduced quality of life that can be attributed to symptoms such as diarrhea and fatigue as well as social and financial issues. This study was conducted to psychometrically assess meaningful change in bowel movement frequency among carcinoid syndrome patients using data from the TELESTAR clinical study.MethodsAn anchor-based approach for deriving meaningful change thresholds consisted of mapping change from baseline bowel movement frequency to other patient-reported assessments of change. These included the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire - Core Questionnaire (QLQ-C30) Diarrhea Symptom responders, the EORTC Gastrointestinal NET questionnaire (GI.NET21) GI Symptom responders, and reported adequate relief at Week 12 (≥ 10-point score decrease from Day 1 to Week 12). Parameters included within-group mean change from baseline to Week 12, t-tests of the change (Wilcoxon rank sum for adequate relief), and effect size.ResultsThere were 135 carcinoid syndrome patients with a mean baseline frequency of 5.7 bowel movements a day. A distribution-based method yielded meaningful change estimates of 0.62 bowel movements a day for overall frequency and 0.83 bowel movements a day at Week 12. Anchor-based analysis indicated a large effect size among patients who reported adequate relief at Week 12 (− 1.58;n = 18;P = 0.014), the QLQ-C30 Diarrhea domain responders (− 1.24;n = 40;P < 0.001), and the GI.NET21 GI Symptoms Domain responders (− 1.49;n = 25;P = 0.005). Exit interview data for meaningful change yielded effect size estimates of − 1.57 for overall change during the Double-blind Treatment Period and − 1.97 for change between Baseline and Week 12.ConclusionsMeaningful change derivation is critical to interpret patient outcomes for evaluating treatment efficacy. In this study, carcinoid syndrome patients experienced clinically meaningful reductions in bowel movement frequency of ≥30% over 12 weeks with telotristat ethyl treatment.Trial registrationNCT01677910.
Fibromyalgia in the workplace: risk factors for sick leave are related to professional context rather than fibromyalgia characteristics— a French national survey of 955 patients
Authors: Laroche F. , Azoulay D. , Trouvin A. P. , Coste J. , Perrot S. 
Published: October 2019

Abstract

Background
Work and workplace factors are important in fibromyalgia management. We investigated factors associated with sick leave in professionally active women living with fibromyalgia.

Methods
A questionnaire for fibromyalgia patients in employment was developed by pain and occupational physicians and patients’ organizations. Women in full-time work, screened for fibromyalgia with the FiRST questionnaire, were recruited for a national online survey. Sick leave over the preceding year was analyzed.

Results
In 5 months, we recruited 955 women, with a mean of 37 days of sick leave in the previous year: no sick leave (36%), up to 1 month (38%), 1 to 2 months (14%), more than 2 months (12%). In the groups displayed no differences in demographic characteristics, fibromyalgia symptoms, functional severity and psychological distress were observed. However, they differed in workplace characteristics, commute time, stress and difficulties at work, repetitive work, noisy conditions, career progression problems and lack of recognition, which were strong independent risk factors for longer sick leave. Sedentary positions, an extended sitting position, heavy loads, exposure to thermal disturbances and the use of vibrating tools did not increase the risk of sick leave.

Conclusions
Women with fibromyalgia frequently take sick leave, the risk factors for which are related to the workplace rather than fibromyalgia characteristics.

Perspective
This is the first study to assess the impact of occupational and clinical factors on sick leave in women living with fibromyalgia. Risk factors were found to be related to the workplace rather than fibromyalgia and personal characteristics. Workplace interventions should be developed for women with fibromyalgia.
Exploitation of sweet lemon residues in the production of essential oils
Authors: Khalid Khalid A. , El-Gohary Ahmed E. , Ahmed Aisha M. A. 
Published: October 2019

Abstract

Background and objective
The constituents of sweet lemon essential oil (EO) have different biological and medical properties. The exploitation of sweet lemon residues in the production of EO is an important means of increasing natural products and disposing of those residues. The aim of this study was to evaluate the EO extracted from various sweet lemon residues such as leaves, flowers, and peels of fruits to find out their content of active substances.

Materials and methods
The EO of different residues of sweet lemon was isolated by hydrodistillation (HD) method, then they were analyzed by GC/MS. Data were statistically analyzed using ANOVA-1.

Results
The content of EO (%) was higher in peels than in flowers or leaves. Citronellal, nerol, and limonene were the major constituents of EO extracted from leaves, flowers, and peels, respectively. All detected components of various oils belonged to four chemical fractions (monoterpene hydrocarbons (MH), oxygenated monoterpenes (OM), sesquiterpene hydrocarbons (SH), and oxygenated sesquiterpenes (OS)). The MH was the major faction of peel EO while the OM was the major fraction of leaf and flower EOs. The SH and OS were formed as the minor fractions in all EOs.

Conclusion
Different variations were observed in sweet lemon EO extracted from various residues which lead to diversity in natural sources of EO production.
Plant response to jasmonates: current developments and their role in changing environment
Authors: Siddiqi Khwaja Salahuddin , Husen Azamal 
Published: October 2019

Abstract
Jasmonates (JAs) are universally known lipid-derived phytohormones which regulate overall plant growth under both abiotic and biotic stresses. They are helpful in developing root and reproductive system in plants. Also, JA signaling triggers gene expression. They coordinate with other plant hormones under changing environmental conditions. JAs alone or sometimes in combination with other plant hormones ameliorate stress conditions. They also participate in upregulation of antioxidant metabolism, osmolyte synthesis, and metabolite accumulation. Pretreatment and/or exogenous application of JA exhibited multi-stress resilience under changing environment as well as other biotic stress conditions. The present review focuses on our current understanding of how plants respond to JAs’ application under extremely low or high temperature, highly alkaline condition, or even when attacked by herbivorous insects/animals. As a consequence of injury, the plant produces defense molecules to protect itself from damage. Their major role and mechanism of action under heavy metal/metalloid-induced toxicity have also been discussed.
Immobilienpreise und Immobilienzyklen und die Rolle von Angebotsbeschränkungen*
Authors: Hilber Christian A. L. 
Published: October 2019

Zusammenfassung
Dieser Artikel untersucht die Auswirkungen von Angebotsbeschränkungen auf die Wachstumsrate und Zyklizität von Immobilienpreisen. Einfache Überlegungen zum Zusammenspiel von Angebot und Nachfrage lassen vermuten, dass Immobilienpreise dort stärker auf lokale Nachfrageschocks reagieren, wo es stärkere Bodennutzungsregulierungen und geografische Barrieren zur Erschließung und Bebauung von Flächen gibt, d. h. wo das Wohnimmobilienangebot preisunelastischer ist. Diese Vermutung wird durch die empirische Evidenz gestützt. Lokale Bodennutzungsregulierungen sind ein besonders entscheidender Faktor, welcher nicht nur lokale Unterschiede im Preiswachstum, sondern auch in der Preiszyklizität erklärt. Allerdings können sich starke Immobilienpreisaufschwünge auch in Standorten etwickeln, in denen die Bautätigkeit langfristig kaum eingeschränkt ist. Ein typisches Merkmal solcher Zyklen ist, dass der Preisverfall aufgrund erheblicher Überkapazitäten tendenziell ausgeprägter ist, als der Anstieg während der vorherigen Boomphase, so dass Immobilienpreise nach dem Preisverfall häufig niedriger sind als vor Beginn des Booms. Die Kurzsichtigkeit von Erschließungsunternehmen und Kreditgebern in Verknüpfung mit kurzfristigen Angebotsrigiditäten oder irrationale Übertreibungen (Euphorie unter Investoren) sind zwei plausible Erklärungen für dieses Phänomen.