bluuebunny/crossref_metadata_2025_split huggingface dataset:
EDUCAÇÃO INCLUSIVA NO COLÉGIO MILITAR DE SALVADOR: a ótica do corpo docente sobre a inclusão escolar
Authors: Lima Thaynara Carvalho , Lopes Julio Cesar Vieira , De Andrade Hamilton Ayres , Freitas Aline Vieira , Reis Rafael Marques 
Published: November 2020

A situação da inclusão de deficientes no ensino regular é uma luta que se prolonga há pouco mais de 40 anos no mundo e há 12 anos no Brasil. No Brasil, as discussões sobre o direito do aluno com necessidades especiais de frequentar a classe comum iniciaram com a Declaração de Salamanca, em 1994, com o tema “Escola para Todos” e incorporou-se na política nacional com a Política Nacional de Educação Especial, onde consta que toda pessoa deficiente tem direito a participar da vida social de maneira o mais “normal” possível, tendo seus direitos reconhecidos pela sociedade em geral. Percebe-se que a inclusão não cabe no paradigma tradicional da educação, requer um modelo diferente das propostas existentes. O presente estudo buscou compreender a percepção do corpo docente do Colégio Militar de Salvador-CMS diante da proposta de implantação da Educação Inclusiva com vistas a se concretizar até o ano de 2020, nesse sistema de ensino. Para isto foi aplicado um questionário aos professores do CMS com questões norteadoras sobre o tema da Educação Inclusiva. Qualitativamente e utilizando-se da Análise de Conteúdo, os dados coletados foram analisados a fim de traduzir os sentimentos dos professores diante da nova proposta de ensino. Os resultados encontrados apontaram para a falta de capacitação dos profissionais, e em consequência disso, mesmo receptivos à implantação da Educação Inclusiva, se sentem inseguros e apreensivos. Concluiu-se que, dada à receptividade dos docentes, é possível a implantação da Educação Inclusiva no CMS desde que atendidas algumas ressalvas, como a capacitação dos profissionais envolvidos. Palavras-chave: Educação Inclusiva; docentes; CMS.
Chemomicrobiomic analysis of glucosamine sulfate, prebiotics and non-steroidal anti-inflammatory drugs
Authors: Gromova O. A. , Torshin I. Yu. , Naumov A. V. , Maksimov V. A. 
Published: November 2020

Introduction. The pharmaceutical drugs used in the treatment of osteoarthritis (OA) differ not only in the mechanisms of anti-inflammatory action but also in the effects on the human microbiome.Purpose. Evaluation of the influence of some drugs used in the therapy of OA on the human microbiome by the method of chemoinformation analysis.Materials and methods. Сomparative chemomicrobiome analysis of glucosamine sulfate (GS), diclofenac, acetylsalicylic acid (ASA), and three prebiotics (lactose, lactulose, fructose) as molecules of comparison. For each substance, estimates of the area under the curve (AUC) were obtained for a representative sampling of human microbiota (38 commensal bacteria). The minimum inhibitory concentrations (MIC) were established for more than 120 pathogenic bacteria.Results. On average, according to a representative sampling of microbiota, the profile of the action of GS on the microbiome was almost identical to the profile of the action of lactose (AUC=0.23±0.18). The most effective growth of the microbiome was provided by fructose and lactulose (AUC=0.58±0.21). The effects of diclofenac and ASA on the commensals of microbiome were comparable to the effects of GS (AUC=0.27±0.22). However, the analysis of the obtained MIC values for pathogenic bacteria showed that diclofenac supported the growth of the pathogenic flora (MIC=35±1.4 μg/ml) to a greater extent than GS (MIC=16±1.5 μg/ml) and ASA (MIC=23±2.2 μg/ml).Conclusion. The effects of GS on the microbiome are comparable to the effects of the prebiotic lactose whereas the inhibitory effect of GS and ASA on pathogenic bacteria is more pronounced than that of diclofenac. The inhibition of pathogenic bacteria by the GS helps to reduce inflammation.
Comparative analysis of antipsychotic drug consumption for inpatient schizophrenia treatment: a retrospective study with 5-year follow-up
Authors: Vaskova L. B. , Tiapkina M. V. , Mikhaylenko E. V. 
Published: November 2020

Aim. The study was aimed to perform a comparative retrospective pharmacoepidemiological analysis of antipsychotic drugs (APD) used for inpatient treatment for schizophrenia.Materials and methods. This retrospective pharmacoepidemiological study included 1077 medical records of patients diagnosed with schizophrenia according to ICD-10 (F20.0-F20.8) selected for the analysis on the base of a psychiatric inpatient hospital in Moscow during 2013-2017. The study design included socio-demographic data (sex, age, education, disability, social status) and clinical-economic data (diagnoses, duration of hospitalization), information on the prescription frequency of drugs and dose regimens were analyzed. The consumption volume of APD was estimated using the WHO ATS/DDD methodology.Results and discussion. It was found that women prevailed (55-71%) with the mean age ranging from 42.8±14.1 to 47.4±14.7 (±SD – standard deviation). In the studied sampling, paranoid schizophrenia dominated (≥70%). Over the analyzed 5-year period, the consumption volume of APDs was characterized by alternating declines and rises (from 154.49 to 208.09 NDDD/100 bed-days). The consumption of atypical APDs decreased by 7% and typical APDs increased by 25% compared to the base year (2013), respectively. The most significant changes in the consumption were identified for APDs of prolonged action (a decrease by 67% compared to 2013). Haloperidol and clozapine (oral forms), which are included in the DU90% segment, remained the leaders in terms of prescription frequency and consumption volume (49.04 and 45.26 NDDD/100 bed days in 2017, respectively). Moreover, trihexiphenydil (used to correct adverse reactions) also had a high frequency of administration and consumption.Conclusion. It was found that 1/2 of all prescriptions were antipsychotic drugs used to treat schizophrenia. The total consumption volume of APDs in 2017 decreased by 9.2% compared to 2013. A high consumption volume is typical for drugs from the subgroup of typical APDs, but atypical APDs prevailed in terms of prescription frequency, which may indicate the prescription of typical APDs in doses exceeding the defined daily dose.
Prevalence of midline diastema according to race in Afghanistan
Authors: Erfan Ozair , Hamed Rahmani Mohammad , Taka Gulbahar 
Published: November 2020

: The main aims of this study were to determine the prevalence of Midline Maxillary diastema according to three common races (Tajik, Pashtoon, and Hazara), sex, and type of dental arch among 999 OPD patients in National and Specialized Stomatology Hospital, Kabul-Afghanistan. : 999 patients in 15-30 years were selected by a systematic random sampling method during the seventh month. Patients were examined directly intra-orally, and information was collected by a single researcher, recorded on pre-prepared questioner forms, and then data analyzed by the SPSS.25 software. The result shows that the prevalence of maxillary midline diastema was 5.8%, that most of them were male 3.3% than females 2.3%. Frequency of midline diastema was more in Tajik race 6.5% than Pashtoon 5.5% and Hazara 3.6%. According to the arch form, midline diastema appearance was mostly detected in the Square arch form at 6.8% than the Ovoid 5.4% and Triangular 4.3%.
The relationship of severity of malocclusion as assessed by IOTN and DAI indices with perception of individuals towards orthodontic treatment-A Questionnarie study
Authors: N Patel Snehal , Bhanat Sheron , Patel Roopal , Patel Dolly 
Published: November 2020

The orthodontic objectives are best achieved when the individual is treated as a whole. It is important to understand the perception of individuals towards the orthodontic procedure. The aim was to evaluate the perception and explore the reasons responsible for the patient wanting to undergo orthodontic treatment. A questionnaire survey was done on 150 individuals reporting to Department of Orthodontics, IOTN and DAI indices on same individuals were recorded. Out of 150 individuals, in this study, 44% individuals were the first one to notice malocclusion, while mothers were the first to notice malocclusion in 34.66% individuals. Most of the individuals expected positive change in aesthetics and self confidence, improvement in dental health and carrier opportunities after orthodontic treatment. TMJ disorder, speech problem and chewing problem were noticed by 4 individuals. It was concluded that 1) Aesthetics was the main factor for seeking orthodontic treatment followed by functional needs. Although aesthetics is the prime concern of individuals seeking for orthodontic treatment, only 12% subjects need indispensible treatment need according to DAI index. Treatment need differs on aesthetics (DAI) and severity of malocclusion (IOTN). When severity of malocclusion is taken into account 88% subjects needed little or borderline treatment. On determining treatment need considering aesthetics 84% subjects needed little or borderline treatment which reflects the awareness of the people concerned about their aesthetics.
A survey to assess the knowledge and attitude of adults from the age group of 18 to 35 Years towards comprehensive orthodontic treatment - A questionnaire based study on adult orthodontics
Authors: Lishoy Rodrigues , Priyal Rajani , Chawla Jamenis Shilpa , Jawale Bhusha , Mahajan Nikhil 
Published: November 2020

Facial appearance has proved to play a key role in social and psychosocial settings. With the advances in Orthodontics, patients have become more aware about the possibility of correcting malocclusions via Braces. Adults however, face some roadblocks before making a confident decision. Understanding these concerns would help provide optimum treatment to such patients. To assess the knowledge and attitude of Adult patients towards Orthodontic treatmentA sample of 205 participants was taken (155 Female and 50 Male) after assessing the sample size within the age group of 18 - 35 year of age. A Questionnaire was created on Google forms and circulated to participants using various social media platforms. The data of responses of participants was analyzed on Google forms application itself with the help of pie charts and graphs.Majority of the participants, both with or without braces asserted that age was not a barrier in getting orthodontic treatment done. They also suggested that it was never too late to undergo Orthodontic treatment and that it could be carried out at any age. Majority of the participants, both treated and non-treated cases also believed that Orthodontic treatment improved function and enhanced the Facial appearance. Participants also believed that Orthodontic treatment would boost their confidence and in no way, would wearing braces affect them socially.This survey based questionnaire helped in assessing the attitude of the general adult population towards adult Orthodontic treatment as a whole. It concluded that age is not a barrier in today’s times for getting orthodontic treatment done. Moreover, Adult Orthodontics not only improved the function, but also the Aesthetics and Self Esteem of the Adult patient undergoing treatment thus eliminating the earlier notion that Braces can be worn only up till a particular age. Prolonged treatment time was one of the causes of reluctance in many participants; however, the other benefits outweighed the time related inconvenience caused by orthodontic treatment.
Krótki kurs „Biochemia z elementami chemii” w ocenie studentów kierunku Ratownictwo Medyczne i propozycje zmian w jego nauczaniu
Authors: Jagusiak Anna , Bentke-Imiolek Anna 
Published: November 2020

Medical studentsâ active involvement in the process of learning and acquiring the knowledge allow to develop passions and skills. The aim of learning should be to increase the number of students involved and satisfied with the learning process. Positive results can be achieved by creating attractive and accessible conditions for students to learn. The search for techniques that increase student involvement, the introduction of new teaching methods and student-oriented education should be a permanent element of modern teaching.
Short courses, particularly with a small number of participants, pose certain organizational challenges. The students start the course often with significantly different initial basic knowledge and background. Additionally small number of students highlights their different expectations. In order to interest all students, a number of modern, active teaching methods should be implemented and applied. Thus we ultimately will achieve the result in increased students satisfaction with the simultaneous achievement of the intended learning outcomes within the course. Moreover one of the most important goals of the course is for the student to acquire such skills and knowledge that will be future-job useful for them.
The aim of this article is to describe the changes planned in the course "Biochemistry with Elements of Chemistry" for Emergency Medical Services. The article focuses on presenting proposals for educational techniques, the application of which will create conditions for improving and equalizing student learning experience. The planned modifications are expected to increase the satisfaction of educators from teaching and students from learning. The basic change in the course concept will be the transition from the general transfer of knowledge in form of information presentation, to student centered learning and their active participation in the learning process. It is planned to introduce remote (on-line) teaching using e-learning platforms, and available online interactive teaching tools such as polleverywhere (https://www.polleverywhere.com/) or perusall (https://perusall.com/inactivity). Moreover, Case based learning, activation techniques embedded in the context of the future emergency services profession, such as role-playing, critical analysis of results or reporting, will be introduced.
Magazynowanie wodoru w obiektach geologicznych
Authors:   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Such Piotr 
Published: November 2020

Hydrogen economy became one of the main directions in EU’s Green Deal for making Europe climate neutral in 2050. Hydrogen will be produced with the use of renewable energy sources or it will be obtained from coking plants and chemical companies. It will be applied as ecological fuel for cars and as a mix with methane in gas distribution networks. Works connected with all aspects of hydrogen infrastructure are conducted in Poland. The key problem in creating a hydrogen system is hydrogen storage. They ought to be underground (RES) because of their potential volume. Three types of underground storages are taken into account. There are salt caverns, exploited gas reservoirs and aquifers. Salt caverns were built in Poland and now they are fully operational methane storages. Oli and Gas Institute – National Research Institute has been collaborating with the Polish Oil and Gas Company since 1998. Salt cavern storage exists and is used as methane storages. Now it is possible to use them as methane-hydrogen mixtures storages with full control of all operational parameters (appropriate algorithms are established). Extensive study works were carried out in relation to depleted gas reservoirs/aquifers: from laboratory investigations to numerical modelling. The consortium with Silesian University of Technology was created, capable of carrying out all possible projects in this field. The consortium is already able to undertake the project of adapting the depleted field to a methane-hydrogen storage or, depending on the needs, to a hydrogen storage. All types of investigations of reservoir rocks and reservoir fluids will be taken into consideration.
Wpływ warunków środowiskowych i instalacyjnych na proces wymiany ciepła w wybranych przemysłowych gazomierzach miechowych
Authors:   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Dudek Adrian 
Published: November 2020

Since 2016, Oil and Gas Institute – National Research Institute (INiG – PIB) has been conducting new research to determine the relationship between ambient temperature and gas temperature in industrial diaphragm gas meters during the measurement, and to develop new recommendations for billing systems using industrial diaphragm gas meters with a throughput of until 25 m3/h. In the first stage, work was carried out, in which the obtained test results confirmed that the heat exchange process in an industrial diaphragm gas meter depends on the ambient temperature, the gas temperature at the inlet to the gas meter, the flow rate of the gas flowing, as well as the casing surface and the gas volume of the gas meter. In the next stage, work was carried out to determine the relationship between ambient temperature and gas temperature at the industrial diaphragm gas meter connection during the measurement. The obtained results undermined the thesis, which indicated that the gas inlet temperature is equal to the gas temperature at the depth of the gas network. In the last stage, work was carried out to determine the course of changes in gas temperature in industrial diaphragm gas meters as a function of ambient temperature and cyclical changes of the gas flow rate, which were to reflect the work of gas meters installed at customers’ premises. The analysis of the obtained test results once again showed a strong dependence of the gas temperature inside industrial diaphragm gas meters on the ambient temperature, but also on the flow rate of gas. The obtained results of laboratory tests will be used to carry out a thermodynamic description of the heat exchange process in an industrial diaphragm gas meter, which would allow the determination of the gas billing temperature as a function of the ambient temperature, the temperature of the inflowing gas and the gas flow rate. The calculated gas temperature values could be used to determine the temperature correction factors applicable when settling gas consumers billed on the basis of measurement with the use of industrial diaphragm gas meters.
Disparities in utilization of sexual and reproductive health services among high school adolescents from youth friendly service implemented and non-implemented areas of Southern Ethiopia
Authors: Haile Bayu , Shegaze Mulugeta , Feleke Tesfaye , Glagn Mustefa , Andarge Eshetu 
Published: November 2020

Abstract
Background: In recent years, much effort was made to improve access to sexual and reproductive health services (SRH) to adolescents and youths in Ethiopia particularly through establishment of youth friendly service (YFS) corners as part of the existing health care facilities. The existing evidences focused on investigating the utilization of SRH services at YFS established areas alone. There is a dearth of evidence which compares the SRH service use between the YFS implemented and non-implemented areas so that evidences can be drawn to suggest on the successes of the expansion of youth friendly corners.Methods: A school-based comparative cross-sectional study was conducted by employing a multistage cluster sampling method. A pre-tested self-administered questionnaire was used to collect data and the collected data were entered in to Epidata version 4.4.1 software and then exported to SPSS version 20 for analysis. χ2 test was used to see a significant difference in SRH service utilization among adolescents from YFS implemented and non-implanted areas. The association between the SRH services utilization and the independent variables were examined using binary logistic regression. Finally, variables having p-value less than or equal to 0.05 in the multivariable logistic regression model were considered as statistically significant.Results: There were a significant difference in the rate of SRH service utilization between YFS implemented (33.8%) and YFS non- implemented (9.9%) areas (χ2=37.49, p<0.001). Higher educational status of mothers (AOR=2.588, 95 % CI: 1.220, 5.491), having open discussion with family (AOR=3.175, 95%CI: 1.624, 6.206), having good knowledge (AOR= 4.511, 95% CI: 2.458, 8.278) and having positive attitude (AOR= 5.084, 95% CI: 2.764, 9.352) were factors positively associated with SRH services utilization.Conclusion: Compared with high schools from YFS implemented areas, the SRH service utilization was significantly lower among students from high schools where health facilities did not implement YFS. There is a need for enhancing efforts to establish YFS corners by the stakeholders at different hierarchies at places where the centers were not established so that SRH service uptake would be improved. In addition, it is better to promote open discussion with adolescents at the family level, and emphasis should be given for women education in the broad sense. Furthermore, wide-range awareness creation strategies should be used to address poor knowledge and negative attitude.
Keratin is not only a Structural Protein in Hair: Keratin-mediated Hair Growth
Authors: An Seong Yeong , Choi Eun Ji , Kim So Yeon , Van Se Young , Kim Han Jun , Lee Jae-Hyung , Han Song Wook , Kwon Il Keun , Lee Chul-Kyu , Do Sun Hee , Hwang Yu-Shik 
Published: November 2020

Abstract
Keratin is known to be a major protein in hair, but the biological function of keratin in hair growth is unknown, which led us to conduct a pilot study to elucidate biological function of keratin in hair growth via cellular interactions with hair forming cells. Here, we show hair growth is stimulated by intradermal injection of keratin into mice, and show that outer root sheath cells undergo transforming growth factor-β2-induced apoptosis, resulting in keratin exposure. Keratin exposure appears to be critical for dermal papilla cell condensation and hair germ formation as immunodepletion and silencing keratin prevent dermal papilla cell condensation and hair germ formation. Furthermore, silencing keratin in mice resulted in a marked suppression of anagen follicle formation and hair growth. Our study imply a new finding of how to initiate hair regeneration and suggests the potent application of keratin biomaterial for the treatment of hair loss.
Associations Between Essential Medicines and Health Outcomes for Cardiovascular Disease
Authors: Steiner Liane , Fraser Shawn , Maraj Darshanand , Persaud Nav 
Published: November 2020

Abstract
Background: National essential medicines lists are used to guide medicine reimbursement and public sector medicine procurement for many countries therefore medicine listings may impact health outcomes.Methods: Countries’ national essential medicines lists were scored on whether they listed proven medicines for ischemic heart disease, cerebrovascular disease and hypertensive heart disease. Linear regression was used to measure the association between countries’ medicine coverage scores and healthcare access and quality scores. Results: There was an association between healthcare access and quality scores and health expenditure for ischemic heart disease (p=<0.001), cerebrovascular disease (p=<0.001) and hypertensive heart disease (p=<0.001). However, there was no association between medicine coverage scores and healthcare access and quality scores for ischemic heart disease (p=0.252), cerebrovascular disease (p=0.194) and hypertensive heart disease (p=0.209) when country characteristics were accounted for. Conclusion: Listing more medicines on national essential medicines lists may only be one factor in reducing mortality from cardiovascular disease and improving healthcare access and quality scores.