bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Changes in Skin and Joint Outcomes and Associated Treatment Changes in Psoriatic Arthritis (PsA): Experience From the Corrona PsA/SpA Registry
Authors: Mease Philip J. , Etzel Carol J. , Huster William J. , Armstrong April W. , Muram Talia M. , Lisse Jeffrey , Rebello Sabrina , Dodge Rhiannon , Murage Mwangi J. , Greenberg Jeffrey D. , Malatestinic William N. 
Published: May 2020

Objective.To characterize skin severity and joint activity outcomes and associated treatment changes in patients with psoriatic arthritis (PsA) through 12 months of follow-up after enrollment in the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry.Methods.Patients ≥ 18 years of age with a diagnosis of PsA and a history of psoriasis between March 21, 2013, and September 30, 2016, were enrolled (n = 647). Demographics, clinical features, and treatment characteristics were collected and stratified by skin severity and joint activity. Change in joint and skin from enrollment to the 12-month visit was classified by change in category of Clinical Disease Activity Index (CDAI) or body surface area (BSA). Tests of association evaluated the relationship between changes in therapy and changes in skin severity and joint activity.Results.Patients with improvement in both joint activity and skin severity saw the largest median reduction in both CDAI and BSA, while those who worsened in both had the greatest median increase in both CDAI and BSA. The majority of PsA patients (> 50%) had no change in skin severity regardless if they had reduced therapy (50%), no therapy changes (54%), or increased therapy (56%;P= 0.5875). However, there was a significant association between changes in therapy and changes in joint activity (P< 0.001). Patients who increased therapy were more likely to have improvement in joint activity (32%) compared to patients who reduced therapy (22%) or had no therapy changes (11%).Conclusion.The clinical implication for our findings suggests the assessment and incorporation of both skin and joint components may be advisable.
Incidence and Prevalence of Juvenile Systemic Lupus Erythematosus in Korea: Data From the 2017 National Health Claims Database
Authors: Kwak Sang Gyu , Park Sung-Hoon , Kim Ji Yoon 
Published: May 2020

Objective.The purpose of the present study was to investigate the prevalence and incidence of juvenile systemic lupus erythematosus (JSLE) in Korea.Methods.The data were collected from the National Health Insurance Claims Database of Korea. JSLE was identified using the diagnostic code M32 from the Korean Standard Classification of Diseases. Patients between 5 and 18 years old, who had at least 1 claim for JSLE from January 1, 2016, to December 31, 2017, as final diagnosis, were analyzed in the study. For prevalent cases, patients who used, at least 1 time, any type of medical services with a diagnostic code of M32 were selected. For incident cases, patients who did not use medical services with the M32 code 1 year prior and who were newly registered in 2017 were defined. Change-point analysis was used to find the age at which changes in prevalence and incidence occurred.Results.The prevalence of JSLE was 6.92 per 100,000 persons and the incidence of JSLE was 2.76 per 100,000 person-years in patients between 5 and 18 years old. The prevalence and incidence of JSLE were higher in females than in males. According to the change-point analysis, we found that the incidence and prevalence of female patients increased rapidly at the ages of 14 and 15 years, respectively.Conclusion.This Korean population-based epidemiological study of JSLE showed similar epidemiologic profiles to Asian population in other studies. The distribution of age, ethnicity, and pubertal status are important factors that influence population estimates of JSLE incidence and prevalence.
Roman power through Rabbinic eyes: tragedy or comedy?
Authors: Hayes Christine 
Published: May 2020

This paper considers the impact of Roman power on the rabbinic perception of history. It argues that while many rabbis continued to view history as a divine comedy arcing towards a happy ending, some suspected that they were players in a dark tragedy. This tragic view, prompted by the encounter with Roman brutality, finds expression in Elisha ben Abuyah’s declaration that there is no moral order to the universe and no resurrection of the dead (p. Ḥag 2:1); in the ministering angels’ outrage over the execution of R. Akiva (b. Ber 61b); in God’s response to the same outrage expressed by Moses (b. Men 29b); and in Rav’s view of the ultimate fate of Rome and Persia (b. Yoma 10a). Interpreted through the lens of the ancient fraternal rivalry between Jacob and Esau, Roman power awakened a deep-seated fear that Esau’s alienated birthright was being restored at Jacob’s expense. Rabbinic anxiety over the identity of the chosen son and the blurred moral distinction between these twinned peoples, is featured in two eschatological fantasies: one in which God behaves like a cruel Roman tyrant (b. AvodZar 2a-3b) and another in which David – that most Roman of Israelite kings – is elevated, against all moral logic, over the pious heroes of old (b. Pes 119a).
Influences of gender and locale on teachers’ job satisfaction
Authors: Shrestha Milan 
Published: May 2020

The gender and locale like personal attributes were associated with the Job satisfaction (JS) of school teachers. This research examined the relationship between gender and JS across locale in school settings. This study followed a post-positivist paradigm with cross-sectional survey as the research design. The researcher used the survey questionnaire among 345 respondents by using cluster sampling and analyzed data with ‘t’ test. Meanwhile, social capital theory was incorporate to discuss the findings. Moreover, the female teachers from urban locale expressed high satisfaction in job than their male colleagues. In contrary, there is no difference in JS between male and female counterparts regarding rural locale except pay, incentive and benefits. However, this JS equipped teachers contribute to determine job effectiveness, high performances, and achievements.
Leveraging Technology to Promote Global Citizenship in Teacher Education in the United States and Brazil
Authors: Kopish Michael , Marques Welisson 
Published: May 2020

With globalization and the increase of technology, collaborative work between institutions from different countries is a reality. Beginning in 2018, two teacher education programs, one in the United States and one in Brazil, developed a partnership to promote collaborative activities in curriculum and instruction, scholarship and research, and for student and faculty exchange. Critical pedagogy and social justice approaches to global citizenship education in teacher preparation guided the partnership’s collaborative activities toward the development of pre-service teachers’ global competencies and ability to integrate technologies as users and educators. This empirical research article presents an exploratory case study of a transnational, collaborative curricular project that leveraged technology in courses for pre-service teachers in the United States (n=12) and Brazil (n=10). The study explores the extent to which course content and activities facilitated pre-service teachers’ development of global competencies and ability to employ emerging technologies for learning and offers implications for practice.
ბიზნეს-გარემოს რეგიონული ასპექტები: კონკურენტუნარიანობა და შესაძლებლობები
Authors: Tsinaridze Ramin , Mzhavanadze Nino 
Published: May 2020

რამინ ცინარიძე
ბიზნესის მართვის დოქტორი
ბათუმის შოთა რუსთაველის ბათუმის სახელმწიფო უნივერსიტეტის ასისტენტ-პროფესორი
ბათუმი, საქართველო
E-mail: ramin.tsinaridze@bsu.edu.ge
http://orcid.org/0000-0002-0444-9740

ნინო მჟავანაძე
ბიზნესის ადმინისტრირების მაგისტრი
წმიდა ტბელ აბუსერისძის სახელობის სასწავლო უნივერსიტეტი
ბათუმი, საქართველო
E-mail: niniamzhavanadze@gmail.com
http://orcid.org/0000-0001-7578-4733

მოკლე აღწერა

შესავალი. თანამედროვე სამყაროში ბიზნესს უდიდესი ად­გი­ლი უჭირავს, ვინაიდან მსოფლიო ეკონომიკა სწორედ ბიზნესზე დგას და ლოგიკურია, რომ ბიზნესი გახდა არამარტო კე­თილ­დღეობისა და ეკონომიკის განვითარების მნიშვნელოვანი და აუცილებელი წყარო, არამედ შესწავლის საგანი, რომელიც პროგ­რე­სით, სირთულეებითა და მუდმივი სიახლეებით ხასიათდება.
კვლევის ძირითადი მიზანია ბიზნესის განვითარების რეგ­ი­ო­ნული ასპექტების, კონკურენტუნარიანობისა და არსებული პოტენციალის, დარგთა თავისებურებებისა და მოქმედი ფაქტ­ო­რე­ბის გამოვლენა-გაანალიზება, ბიზნეს-სექტორის განვითარების ტენ­დენციების მიმოხილვა აჭარის ავტონომიური რესპუბლიკის მაგ­ალითზე.
საკვლევი თემა ღირებული და საინტერესოა იმ თვალ­საზ­რი­სითაც, რომ როგორც ქვეყანა, ისე აჭარის ავტონომიური რეს­პუ­ბ­ლიკა კერძო სექტორის ჯერ კიდევ განვითარების ეტაპზეა, ბი­ზ­ნე­სი ჯერ კიდევ მუდმივ ცვლილებებთან შეგუების ეტაპს გადის და დინამიკის გარკვეულ ეტაპზე დგას (მაგ. საკანონმდებლო ცვ­ლი­ლებები, გლობალური კონკურენცია, ტექნოლოგიური ჩა­მორ­ჩე­ნილობა და ა.შ.). აქედან გამომდინარე, საკითხი აქტუალური და მნიშ­ვნელოვანია.
სწორედ აჭარის ავტონომიური რესპუბლიკა წარმოადგენს ბი­ზ­ნესის დაწყებისათვის ერთ-ერთ ხელსაყრელ გარემო პირობების მქ­ონე ადგილს, სადაც აშკარადაა გამოკვეთილი ბიზნეს სა­ქმ­ი­ა­ნო­ბის უპირატესობები. ბიზნესის განვითარების ტენდენციები და დღ­ევანდელი მდგომარეობით არსებული ვითარება რეგიონში, იძ­ლე­ვა შესაძლებლობას უფრო მეტი ინტერესი და ყურადღება იქნას გა­მოჩენილი ინვესტიციების მოზიდვაზე და რეგიონის ეკ­ონო­მი­კურ განვითარებაზე. მართალია რიგი საკითხები, რომლებიც ეხ­ე­ბა არსებულ ბიზნეს-გარემოს და მიმდინარე ეკონომიკურ პრო­ცე­სე­ბს აჭარის ავტონომიური რესპუბლიკა საკმაოდ გამოკვლეულია, თუ­მ­ცა ჯერ კიდევ ბოლომდე არ არის შესწავლილი, შესაბამისად ბიბ­ლიოგრაფიაში მიმოხილული ნაშრომები იძლევა შესაძ­ლე­ბლ­ო­ბას მიმოვიხილოთ აჭარის რეგიონის ზოგადი ბიზნეს-გარემო, გა­მოვ­კვეთოთ გარკვეული პრობლემები და ტენდენციები.
კვლევისას გამოყენებულია თვისებრივი, რაოდე­ნო­ბ­რი­ვი და სტატისტიკური მეთოდები. მონაცემების სი­ზუსტი­სა­თ­ვის ასე­ვე გამოყენებულ იქნა შეგროვებითი და შედარებითი მეთოდები. მო­ცემული კვლევის ბოლოს შე­მუ­შა­ვ­ებულია სათანადო და­­ს­­კვ­ნები და რეკომენდაციები.
საკვანძო სიტყვები: რეგიონული ბიზნეს-გარემო, რე­გ­იო­ნული ასპექტები, აჭარის ავტონომიური რესპუბლიკა, რეგიონული პოტენციალი, ბიზნესის განვითარების ტენდენციები
European anthropogenic AFOLU greenhouse gas emissions: a review and benchmark data
Authors: Petrescu Ana Maria Roxana , Peters Glen P. , Janssens-Maenhout Greet , Ciais Philippe , Tubiello Francesco N. , Grassi Giacomo , Nabuurs Gert-Jan , Leip Adrian , Carmona-Garcia Gema , Winiwarter Wilfried , Höglund-Isaksson Lena , Günther Dirk , Solazzo Efisio , Kiesow Anja , Bastos Ana , Pongratz Julia , Nabel Julia E. M. S. , Conchedda Giulia , Pilli Roberto , Andrew Robbie M. , Schelhaas Mart-Jan , Dolman Albertus J. 
Published: May 2020

Abstract. Emission of greenhouse gases (GHGs) and removals from land, including both
anthropogenic and natural fluxes, require reliable quantification, including
estimates of uncertainties, to support credible mitigation action under the
Paris Agreement. This study provides a state-of-the-art scientific overview
of bottom-up anthropogenic emissions data from agriculture, forestry and
other land use (AFOLU) in the European Union (EU281). The data integrate
recent AFOLU emission inventories with ecosystem data and land carbon models
and summarize GHG emissions and removals over the period 1990–2016. This
compilation of bottom-up estimates of the AFOLU GHG emissions of European
national greenhouse gas inventories (NGHGIs), with those of land carbon models
and observation-based estimates of large-scale GHG fluxes, aims at improving
the overall estimates of the GHG balance in Europe with respect to land GHG
emissions and removals. Whenever available, we present uncertainties, its
propagation and role in the comparison of different estimates. While NGHGI
data for the EU28 provide consistent quantification of uncertainty following
the established IPCC Guidelines, uncertainty in the estimates produced with
other methods needs to account for both within model uncertainty and the
spread from different model results. The largest inconsistencies between
EU28 estimates are mainly due to different sources of data related to
human activity, referred to here as activity data (AD) and methodologies
(tiers) used for calculating emissions and removals from AFOLU sectors. The
referenced datasets related to figures are visualized at https://doi.org/10.5281/zenodo.3662371 (Petrescu et al., 2020).
Crayfish population genetic studies: assessment and trends
Authors: Figiel Chester R. 
Published: May 2020

Abstract
I surveyed the peer-reviewed literature for studies on crayfish population genetics over the last 20 years (1996 to 2015). My objectives were to determine if there is research disparities based on crayfish conservation status, ecological group, geographic location, and genetic methods used. Additionally, I wished to determine overall trends in crayfish genetics related to population variability, systematics, and technique development. An extensive literature search yielded 201 peer-reviewed articles with genetic information published on 335 of the 590 crayfish species found worldwide. The majority of peer-reviewed articles took place in Europe and Australia/Oceania despite the fact that crayfish biodiversity is greatest in North America. Crayfish within each ecological group (primary burrowers, lotic inhabitants, lentic inhabitants, and stygobitic species) are represented in these published papers. I found published articles on ~ 57% of the estimated 590 extant species. Further, of the 173 species listed as critically endangered, endangered, vulnerable, or as near threatened by the International Union for Conservation of Nature, I found published research on ~ 62% of these species in these classifications thus indicating a knowledge gap for many imperiled species. This lack of basic genetic (and ecological) information is significant as species designation is often used to determine where we should focus our conservation actions. Understanding what constitutes a single interbreeding population and identifying taxonomic designations are priorities for defining conservation management plans.
Plotino e o argumento do terceiro homem
Authors: Pitteloud Luca 
Published: May 2020

This paper proposes to pose the question of a possible position of Plotinus with regard to the Argument of the Third Man (TMA): first, we will examine if it is possible to attribute to Plotinus a position as regards TMA such as it appears in the Parmenides, in particular with regard to the premise which affirms the self-predication (SP) of the Forms. Next, we will briefly consider how the question of the soul-body relationship can, to some extent, provide a better understanding of why Plotinus does not bother to give an explicit objection to TMA. Finally, we will analyze how the theory of two kinds of resemblance strikes a fatal blow to the spirit of TMA.
Land Use Influence on Some Soil Physical and Chemical Properties of an Alfisol at Forestry Research Institute of Nigeria
Authors: Onemayin J. J. , Olayiwola V. A. , Abiodun F. O. , Musa F. B. , Idris R. S. 
Published: May 2020

Land use is characterized by the arrangements, activities and inputs people undertake in a certain land cover type to produce, change or maintain it. Changes in land use cover also have a drastic effect on chemical and biological properties of soil and hence change the quality of the soil. A study was conducted to examine the effect of land use types on soil physical and chemical properties within an Alfisol in the arboretum of Forestry Research Institute of Nigeria (FRIN). Soil samples were collected at two soil depths (0-15cm and 15-30 cm soil depths) under these plantations: Nauclea diderrichii (NP), Gmelina arborea (GP), Terminalia superba (TP), Arable crop land (AC) and a Fallowed Land (FL) and were analysed for some selected soil physical and chemical properties. The experiment was a completely randomize design (CRD) with six replications. Data collected was subjected to Analysis of Variance (ANOVA) and means were separated using Duncan Multiple Range Test (DMRT). Results revealed that higher content of clay was recorded in 0 to 15 cm depth of both GP (15.00%) and FL (15.00%) plantation lands whereas higher clay content was recorded at 15 to 30 cm depth in Arable crop land (23.00%) and Nauclea plantation land (21.00%). Higher total nitrogen (TN) was observed in FL (1.44%) while TN availability decreases in the order AC>GP>NP>TP. Higher values of soil Organic Carbon (16.74%), Available phosphorus (2.15 Cmol/kg) and Organic matter (28.86%) were obtained under FL as compared to the other land use fields at 0 to 15 cm depth. Bulk density and porosity were highly variable among different land use types and ranged from (1.039 - 1.415) g cm−3 and (17.99 - 48.87)%. The information generated from the present study suggested fallowed land use as the best land use system because of its higher soil organic matter management, as it improves the soil structure and this will assist in developing sustainable and ecologically stable land use management strategies for the study area.
TiO2 Nanoparticles Enhancing Germination, Growth and Yield of Rice
Authors: Debnath Keya , Das Aparajita , Das Bimal , Karfoma J. 
Published: May 2020

Background: Titanium dioxide (TiO2) NPs are used in agriculture to increase seeds germination and seedlings growth and can improve yield by approximately 30%. The present experimental investigation demonstrated the effect of nanoparticles (NPs) Anatase - TiO2 (<100 nm size) on germination, seedling growth and yield attributing traits of rice.
Methods: Rice seeds were treated with six concentrations (0, 10, 20, 50, 80 and 100 ppm) of nanoTiO2 and placed in Petri plates. Some amount was sown in the field following Randomized Block Design (RBD) with three replications for each treatment.
Results: Application of TiO2 NPs significantly enhanced germination, seedling growth and yield traits for most of the concentrations as compared to the control. About 85% significant improvement of seed germination occurred by 20 ppm of TiO2 NPs. The results of TiO2 treated samples were higher in almost all the growth parameters, but the treatment was highly effective for 20 ppm followed by 50 ppm for grain yield. The response to nano-treatment on seed germination along with yield traits suggested the optimum TiO2 dose limit on these characters on rice.
A Cross-sectional Assessment of Quality of Life among Pharmacy Academics
Authors: Iqbal Muhammad Shahid , Al-Saikhan Fahad I. , Iqbal Muhammad Zahid 
Published: May 2020

Introduction: These days, living a good quality life has become a luxury rather than a necessity and investigating the quality of life (QoL) across teaching professionals seems to be beneficial. This study aimed to determine the association between demographic and socioeconomic variables and the QoL among pharmacy academics.
Methods: Stratified random sampling was applied to collect data using a pre-validated and self-administered questionnaire the Duke Health Profile (DHP). Statistical Package for Social Science (SPSS) ver. 22.0 was used to analyze the descriptive and inferential data.
Results: One hundred and fifty-five pharmacy academics were included in this study where majority 98 (63.2%) were males and 57 (36.8%) were females. The majority 74.2% weremarried and 68.4% were having more than 5 years of teaching experience. A total of 123 ofthe pharmacy academics were more than 35 years old which accounted for 79.4% of the respondents. Various determinants like age, residence, gender, administrative position, marital status, monthly income, and teaching experience are the main factors affecting QoL among pharmacy academics.
Conclusion: From the present study it could be concluded that QoL among pharmacy academics was significantly influenced by numerous socio-economic and demographic determinants.
Association between extremely long working hours and musculoskeletal symptoms: A nationwide survey of medical residents in South Korea
Authors: Sung Hyoju , Kim Ja Young , Kim Ji-Hwan , Punnett Laura , Lee Hyemin , Kim Seung-Sup 
Published: May 2020

Abstract

Objectives
It has been reported that South Korea ranked as one of the longest-working nations among OECD countries. This study sought to examine the association between long working hours and musculoskeletal pain among Korean medical residents.

Methods
We analyzed a cross-sectional survey of 1,077 medical residents in South Korea. Working hours per week were categorized as follows: &lt;60, 60-79, 80-99, and ≥100. Musculoskeletal pains (ie, upper limb, lower limb, and low back pain) over the past 3 months were categorized into three groups: no pain, pain without interfering with work, and pain interfering with work. Multinomial logistic regression was used to examine the association between long working hours and musculoskeletal pains after adjusting for covariates.

Results
We found that the average working hours of medical resident was 85.6 hours per week in South Korea. Compared to the medical residents working &lt;60 hours, those working ≥100 hours per week were more likely to have upper limb pain (PR: 1.77, 95% CI: 1.37, 2.30) interfering with work or low back pain (PR: 2.15, 95% CI: 1.51, 3.06) interfering with work, whereas no statistically significant association was observed in the analysis of lower limb pain.

Conclusions
This study suggests that extremely long working hours are associated with upper limb and low back pain interfering with their work among Korean medical residents.
The impact of extended half‐life factor concentrates on prophylaxis for severe hemophilia in the United States
Authors: Malec Lynn M. , Cheng Dunlei , Witmer Char M. , Jaffray Julie , Kouides Peter A. , Haley Kristina M. , Sidonio Robert F. , Johnson Kelsey , Recht Michael , White Gilbert , Croteau Stacy E. , Ragni Margaret V. 
Published: May 2020

AbstractWith licensure of extended half‐life (EHL) factor products and the changing landscape of available hemophilia products, patients and providers have options for less treatment‐intense prophylaxis. The impact of these products in clinical practice to date remains understudied.We aimed to quantify the use of EHL products in prophylaxis in the US using the ATHN‐dataset, a database of 145 ATHN‐affiliated hemophilia treatment centers (HTCs). Further, we aimed to quantify the impact of EHL on key hemophilia indicators including annualized bleed rates (ABRs), hemophilia joint health scores (HJHS) and quality of life (QOL) metrics. The use of EHL vs standard half‐life (SHL) products in severe hemophilia was compared between June 2018 and March 2019 using the ATHN‐dataset. A cohort of patients was also recruited from seven participating HTCs in order to compare ABR, HJHS and QOL between product classes.By March 2019 the number of individuals with severe Hemophilia A (SHA) receiving EHLs remained relatively stable (28.4%), whereas the number of prescribed non‐factor products increased to 7.1%, with a diminishing majority of patients (64.0%) continuing to receive SHLs. The majority of patients with severe hemophilia B (SHB) received treatment with EHLs including 57.5% by March 2019. There was a trend toward lower ABR with use of EHLs in SHA and SHB, although this did not result in improved HJHS nor QOL.EHL use in the United States in severe hemophilia continues to increase, although at a slower rate in SHA with the availability of non‐factor therapy. The impact of the EHL therapies in clinical practice should continue to be examined prospectively.