bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wann mit der intensivierten Insulintherapie beginnen? – Der BeAM-Wert zur besseren Abschätzung einer prandialen Insulintherapie bei Typ-2-Diabetes mellitus
Authors: Kress Stephan , Borck Anja , Zisman Ariel , Bramlage Peter , Siegmund Thorsten 
Published: April 2020

ZUSAMMENFASSUNGDer BeAM-Wert ist ein kumulatives Maß der postprandialen Hyperglykämie. Er lässt sich aus der Blutglukosekonzentration vor dem Zubettgehen (Be) und der darauf folgenden Nüchternglukose am Morgen (AM) errechnen. In zwei retrospektiven Auswertungen von Daten aus Phase-III- und -IV-Studien wurde der Nutzen des BeAM-Wertes als Entscheidungshilfe für den Beginn der intensivierten Insulintherapie bei Typ-2-Diabetes mellitus (T2DM) Patienten unter basalinsulinunterstützter oraler Therapie (BOT) dargelegt. Bei Patienten, deren Therapie von einer oralen antidiabetischen Therapie (OAD) auf eine basalinsulinunterstützte orale Therapie umgestellt wird, steigen Ausmaß der postprandialen Hyperglykämie und der BeAM-Wert an bei gleichzeitig sinkendem HbA1c-Wert und Nüchternglukose. Nach Umstellung auf eine intensivierte Insulintherapie fällt der BeAM-Wert und das Ausmaß der postprandialen Hyperglykämie geht zurück. Insbesondere Patienten mit einem BeAM-Wert > 50 mg/dl profitieren von der Umstellung auf eine intensivierte Insulintherapie. Ein negativer BeAM-Wert spricht gegen den Einstieg in die prandiale Insulintherapie.
Middle East Respiratory Syndrome Coronavirus and Severe Acute Respiratory Syndrome Coronavirus
Authors: Al-Tawfiq Jaffar A. , Memish Ziad A. 
Published: April 2020

AbstractEmerging infectious diseases continue to be of a significant importance worldwide with the potential to cause major outbreaks and global pandemics. In 2002, the world had witnessed the appearance of the severe acute respiratory syndrome coronavirus in China which disappeared abruptly within 6 months. About a decade later, a new and emerging novel coronavirus named the Middle East respiratory syndrome coronavirus (MERS-CoV) was described in a patient from Saudi Arabia. These two coronaviruses shared multiple similarities in the epidemiology, clinical presentations, and posed challenges in its prevention and management. Seven years since its discovery, MERS-CoV continues to be a lethal zoonotic pathogen capable of causing severe pneumonia with high case fatality rates and the ability to cause large health care-associated outbreaks.
Quality of Life in Children with Epilepsy
Authors: Prajapati Mukesh Kumar , Dwivedi Deepak , Bajaj Naresh 
Published: April 2020

Abstract
Objective The main aim of this study was to assess quality of life in children with epilepsy.
Materials and Methods A prospective observational study was conducted in Regional Early Intervention Centre of the Department of Pediatrics Tertiary Care Hospital in central India. This study included 120 children with epilepsy aged between 2 and 18 years. In this study, we assessed the quality of life in children with epilepsy with the help of Pediatric Quality of Life Inventory (PedsQL). We further analyzed the quality of life in various dimensions. For the statistical analyses for SPSS version, 20 was used, chi-squared and Fisher's exact test was used for categorical variables, and Student's t-test was used for quantitative variables. Linear regression analysis was done for multivariate analysis.
Result Mean total PedsQL score for total cohort was 70.96. The cognitive dimension of epileptic children was more affected than physical, social, and emotional dimensions. Factors associated with lower PedsQL scores in epilepsy patients were associated with long duration of epilepsy, polytherapy, male gender, low head circumference, presence of intellectual disability, and refractory epilepsy.
Conclusion Epilepsy affects the quality of life in children across all age groups. Among epilepsy indicators, polytherapy, refractory epilepsy, and duration of epilepsy were the most important factors associated with poor quality of life. We can conclude that every effort should be made to decrease the duration of treatment and minimize the number of drugs for improving the quality of life in this patient cohort.
Stability of Poiseuille-type flows in an MHD model of an incompressible polymeric fluid
Authors: Blokhin A. M. , Tkachev D. L. 
Published: April 2020

Abstract
A generalization of the Pokrovskii-Vinogradov model for flows of solutions and melts of incompressible viscoelastic polymeric media to the case of nonisothermic flows in an infinite plane channel under the effect of a magnetic field is considered. A formal asymptotic representation is derived for the eigenvalues of the linearized problem (the basic solution is an analogue of the Poiseuille flow of a viscous fluid in the Navier-Stokes model) as their absolute value increases. A necessary condition for the asymptotic stability of an analogue of the Poiseuille shear flow is deduced.
Bibliography: 22 titles.
Three-webs
Authors: Shelekhov A. M. 
Published: April 2020

Abstract
Local differential-geometric properties of three-webs

formed on a

-dimensional manifold by foliations of codimension

,

and

, respectively, are considered. In particular, three-webs defined by complex analytic functions of

complex arguments belong to this class of webs. The structure equations of a three-web

in an adapted co-frame (in particular, in a natural co-frame) are deduced; the canonical connection

on the manifold of a web

is introduced; formulae are obtained to calculate (in a natural co-basis) the components of the first structure tensor of a three-web

in terms of the derivatives of the function of this web. Three special classes of three-webs

are considered in detail: regular and group three-webs and also three-webs

generated by holomorphic functions.
Bibliography: 17 titles.
A canonical basis of a pair of compatible Poisson brackets on a matrix algebra
Authors: Garazha A. A. 
Published: April 2020

Abstract
Given an arbitrary complex matrix

and a generic matrix

we find a canonical basis for the Kronecker part of the bi-Lagrangian subspace with respect to the corresponding Poisson brackets on the Lie algebra

, and also find a system of functions in bi-involution corresponding to this basis. In particular, for nilpotent matrices

we prove that all nonzero functions obtained by applying the Mishchenko-Fomenko argument shift method to the coefficients of the characteristic polynomial form the Kronecker part of the complete system of functions in bi-involution.
Bibliography: 9 titles.
Phylogenetic linguistic evidence and the Dene-Yeniseian homeland
Authors: Yanovich Igor 
Published: April 2020

AbstractSicoli & Holton (2014)(PLoS ONE 9:3, e91722) use computational phylogenetics to argue that linguistic data from the putative, but likely, Dene-Yeniseian macro-family are better compatible with a homeland in Beringia (i.e., northeastern Siberia plus northwestern Alaska) than with one in central Siberia or deeper Asia. I show that a more careful examination of the data invalidates this conclusion: in fact, linguistic data do not support Beringia as the homeland. In the course of showing this, I discuss, without requiring a deep mathematical background, a number of methodological issues concerning computational phylogenetic analyses of linguistic data and drawing inferences from them. The aim is to contribute to making computational phylogenetics less of a black box for historical linguists. I conclude with a brief overview of the current evidence bearing on the Dene-Yeniseian homeland from linguistics, archaeology, folklore studies and genetics, and suggest current best practice for linguistic phylogenetics, the use of which would have helped to avoid some of the problems in Sicoli and Holton’s Dene-Yeniseian study, and in turn the percolation of those problems into subsequent synthetic interdisciplinary research.
The history of tense and aspect in the Sogeram family
Authors: Daniels Don 
Published: April 2020

AbstractThis paper presents an overview of the tens-aspect system in the Sogeram languages of Papua New Guinea. Taking the Proto-Sogeram reconstruction in Daniels (2015,2020) as a starting point, I outline the innovations that have taken place in daughter languages and discuss the patterns of change that emerge. The study confirms a variety of known cross-linguistic tendencies, such as the common occurrence of the analytic-to-synthetic and aspect-to-tense pathways of change. More notable trends include the diachronic stability of the present and most remote past tenses; the instability of the middle pasts and future; the stability of the relative semantic ordering of tenses; the absence of a pathway leading from relative-tense to absolute-tense marking; and the ability of innovative tenses to be inserted anywhere into the five-way tense system of Proto-Sogeram. The study also illustrates how featural systems can interact over time, at first by introducing a new feature value in one system which can combine with values from another (as with the Manat habitual), and then, if the featural distinction is lost, creating a pattern of distributed exponence (as in Mum).
A Solution to VRPTW Based on Improved GA-AMMAS Algorithm
Authors: Han Ming , Wang Ya-Bin 
Published: April 2020

Abstract
Vehicle routing problem with time windows (VRPTW) is a NP difficult problem, and it has important applications in military logistics, especially the distribution of wartime military equipment, materials and spare parts. In the last decade, numerous new methods for VRPTW have sprung up. However, few researches have been made in the study of VRPTW of wartime distribution. Hence, a two-stage solution is proposed in this paper to solve the VRPTW in complex dynamic environment during the war. That is, static route optimization in the pre-planning stage and dynamic route re-planning in the execution stage for sudden or changing enemy threats. An improved hybrid algorithm of Genetic algorithm and adaptive maximum-minimum ant system (GA-AMMAS) is designed in this paper for the solution of the model above.
Intelligent Text Scoring System Based on Deep Learning
Authors: Lin Qi 
Published: April 2020

Abstract
In view of the lack of unified standards for emerging local service industries and the impact on users’ reasonable choices, this thesis takes the field of B&B as an example to design an analysis and scoring system based on massive online data. The system first obtains massive online data, including text-type data, through web crawlers. Then analyze and pre-process the captured information to build a corpus; use Chinese word segmentation and label clustering to mine the keywords in the listing introduction and comments. The sentiment polarity of the tenant reviews was analyzed based on the support vector machine (SVM) and sentiment lexicon. Finally, an optimized scoring system was obtained.
Research on collapsed (α, k)-NP-community on signed graph
Authors: Zhang Jiyuan , Yang Yan 
Published: April 2020

AbstractIn social network, the departure of critical users can lead to the disintegration of the entire community, i.e., lead a large number of other users to drop out. This paper aims to find the critical users in the community and prevent the whole community from disintegrating. Most of the other research work is carried out on the unsigned network. In this paper, we study this problem on a signed network and propose a new community model (α, k)-NP-community. Specifically, the nodes in the community model should satisfy the maximum subgraph with no less than ak good friends (positive neighbor) and no more than k enemy (negative neighbor). We propose an effective algorithm to find (α, k)-NP-community. In order to identify the critical users of (α, k)-NP-community, we propose the problem of collapsed (α, k)-NP-community: given a signed graph G, integers α, k, our goal is to find such nodes in graph G, the departure of the best collapser will lead to the smallest (α, k)-NP-community. We prove that the problem is NP-hard. Finally, we present two lemmas to apply the αKCA algorithm, which effectively reduced the number of candidate nodes and accelerated the search process. The results of extensive experiments on four real datasets demonstrate the effectiveness and efficiency of our algorithms.
An Analysis of Macro Effects of Drunk Driving Penalty on Motor Vehicle Traffic Accidents in China
Authors: Hui Zhang 
Published: April 2020

Abstract
The effects of the law to punish drunk driving after coming into force in China can be seen in some media reports, while academic statistical analysis and evaluation are rare. In this study, the intervention analysis model of the law was constructed, by which the data of the number of motor vehicle accidents per 10,000 people in China, the number of injuries per 10,000 people and the number of deaths per 10,000 people were fitted, the macro effects of “drunk driving in punishment” on motor vehicle accidents in China were analyzed. The results showed that “drunk driving penalty” did not change the trend of motor vehicle accidents in China statistically.
The Hot-line Work Robot for Power Distribution Network
Authors: Yu Yan , Zhou Zhanfan , Liu Weidong , Yang Yuhang , Xu Xianjin 
Published: April 2020

Abstract
Aiming to solve the problems of safety, low efficiency and large volume of existing distribution network robots, a new distributed live working robot based on the master-slave control algorithm with weak stiffness and large lag is designed in this paper. The smaller robot body is used in the multi-level three-dimensional insulation isolation and shielding measures of the robot which realize the quick replacement of the working end such as the general mechanical, control and electrical interfaces. In the control system, ARM microprocessor is the signal processing terminal, displacement sensor and force sensor are the intermediary of signal measurement and closed-loop feedback respectively, which realizes the remote operation of the operator.
Fermentative quality of silage as affected by protein level in the ensiled material: A meta-analysis
Authors: Jayanegara A , Wardiman B , Kondo M , Ridla M , Nahrowi  , Laconi E B 
Published: April 2020

Abstract
Ensiling of high-protein forages like alfalfa, indigofera, cassava and moringa, however, are characterized by considerable extent of proteolysis. This study aimed to perform a meta-analysis from various published experiments regarding the effect of protein level on fermentative quality of silage. Papers reported data on protein contents of silages and their fermentative characteristics were collected and integrated in a database. A total of 15 papers and comprised of 155 data points were included. The ensiled materials were peas, wheat, barley, maize, sorghum, alfalfa and mucuna. The ensiling period varied from 20 to 303 days. Data were statistically analyzed by using the mixed model methodology. Studies from different papers were treated as random effects whereas protein level in silage was treated as fixed effect. The model statistics used was p-value. Results revealed that higher protein level led to an increase of DM loss in silage (p<0.01). Protein was negatively correlated with NDF (p<0.001) and ADF (p<0.05). Increasing protein level elevated pH value of the silage (p<0.05) and tended to increase acetate concentration (p<0.1). Ethanol concentration was elevated by increasing silage protein level (p<0.05). Higher silage protein level increased organic matter digestibility (OMD), lactic acid bacteria (LAB) population, nitrate and ammonia concentrations of the silage (p<0.05). It can be concluded that higher protein level induces proteolysis in the silage and reduces its fermentative quality.
Composting of grass clippings using different commercial microbial activators
Authors: Agustina W , Sriharti  
Published: April 2020

Abstract
A study was conducted on the utilization of biomass organic waste in the form of grass-clippings waste to make compost. The study proposed to determine the effect of different types of activators used on the temperature, duration of composting and the characteristics of the compost produced. The material used for making compost is grass-clipping, mixed with goat manure and rice bran, then inoculated using three types of commercial activators, EM4, Green Phoskko (GP-1) and Agrisimba. Observation of temperature changes during composting was carried out every day. Compost products were then tested for quality including pH, water content, C-Organic, total nitrogen, C/N ratio, and P2O5 levels. The test results showed that the temperature changes of the sample with Green Phoskko and Agrisimba activators were almost the same, but both were different from the sample using EM4 activators. The composting process of all sample treatments lasted for 14 days. The quality of compost produced from the three treatments has met the quality requirements according to the Indonesian National Standard SNI 19-7-30-2004 regarding compost from domestic organic waste.
Nutrient digestibility of broiler chicken fed diets supplemented with probiotics phytase-producing
Authors: Anggraeni A S , Suryani A E , Sofyan A , Sakti A A , Istiqomah L , Karimy M F , Darma I N G 
Published: April 2020

Abstract
Phytic acid is an anti-nutrition substance due to its ability to bind minerals such as Mg, Fe, Zn, Mn, Ca, and enzyme proteins resulted in decrease in mineral solubility. Phytic acid levels can be reduced by phytase [myo-inositol hexacryphosphate phosphohidrolase]. Microbial phytase can come from fungi, bacteria, and yeast sources. This research was conducted with the aims to evaluate the effect of probiotics phytase-producing supplementation as feed additive on nutrient digestibility of broiler. This study was performed in a completely randomized design for the environmental design, which consist of five treatments. Negative control (without probiotics phytase-producing), LAB (Lactobacillus plantarum A1-E) phytase-producing, yeast (Candida tropicalis TKD-3) phytase-producing, probiotic consortium (L. plantarum A1-E and C. tropicalis TKD-3) and positive control (commercial probiotic). The observed variables are feed intake, energy intake, excreta weight, energy excretion, nitrogen intake, nitrogen excretion, nitrogen retention, apparent metabolizable energy (AME), true metabolizable energy (TME), apparent metabolizable energy corrected for nitrogen (AMEn) and true metabolizable energy corrected for nitrogen (TMEn). Data were analyzed by using analysis of variance (ANOVA) and followed by Duncan’s multiple range test to distinguish the effect of different treatment mean. The results of variation analysis on AMEn and TMEn showed significant different while another parameter showed no significant difference between treatments. The use of C. tropicalis TKD-3 as probiotics phytase-producing on broiler chicken diet increase nutrient digestibility, especially apparent metabolic energy corrected nitrogen, and true metabolic energy corrected nitrogen.
Effects of spinach tree leaves and high concentrates diets supplemented with micro minerals on in vitro rumen fermentation profiles
Authors: Herdian H , Sofyan A , Sakti A A , Karimy M F , Fitriana E L , Laconi E B 
Published: April 2020

Abstract
The effects of different level Spinach tree leaves Cnidoscolus aconitifolius, and high concentrate diets supplemented with micro minerals on in vitro rumen fermentation profiles were investigated. The basal diets consisted of 30% king grass (Pennisetum hybrid), and 70% concentrate. The mineral mix consists of FeCl2.4H2O; MnCl2.4H2O; CuSO4.5H2O; ZnSO4.7H2O; and CoCl2.6H2O. The treatments were Basal Ration (B), B+5% C. aconitifolius leaf (BC), B+2% mineral mix (BM), and B + 5% C. aconitifolius leaf + 2% mineral mix (BCM). The treatment diets were incubated for 48 h. Completely Randomized Design with one-factor consists of four treatments, and three replications were used in this experiment followed by One Way Analysis of Variance for statistical analysis. The gas production, N-ammonia, propionate, dry matter, and organic matter digestibility decreased significantly (p<0.05) by the treatment of mineral mix BM, BCM with the lowest value was found on BCM. Rumen microbial protein synthesis and pH was not influenced by the treatments of spinach tree alone (BC) (p>0.05) but increased significantly (p<0.05) when mineral mix treatments BM and BCM with the highest value at BCM. No effect (p>0.05) were observed for Protozoa population, methane production, acetate, and butyrate proportion. It was concluded that supplementation of C. aconitifolius leaves to the high concentrate diet has no effect on the fermentation variables whereas it combination with micro minerals reduced the fermentability and increased microbial protein synthesis in the rumen.
Antimicrobial activity of quinine derivatives against human pathogenic bacteria
Authors: Antika L D , Triana D , Ernawati T 
Published: April 2020

Abstract
Nowadays, the antimicrobial resistance is considered as one of the greatest concern facing human health, as many of bacterial strains had become resistant to available antibiotics. The misuse of antibiotics has potentially reduced the efficacy of drugs, concurrent with the increase of bacterial resistance to commercially available drugs. Therefore, the discovery of effective antimicrobial agents are desperately needed to overcome this epidemic, especially from traditional medical plants and their derivatives. Quinine is a natural alkaloid from the bark of the cinchona tree that has been used for years as an antimalarial drug. Various literatures also regarded an antibacterial effect of quinine against both Gram-positive and Gram-negative pathogenic microorganisms. With this vision, a series of some novel quinine derivatives were synthesized and their biological activities against pathogenic bacteria were assessed. This present study therefore attempted to examine the antimicrobial properties of quinine-derived compounds and their Minimal Inhibitory of Concentration (MIC) against common pathogenic bacteria strains, e.g. Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Bacillus substillis. Disk diffusion test was performed for screening of antimicrobial activity of quinine derivatives. The results were evaluated and compared with references drug streptomycin. It was found that quinine derivatives showed moderate antimicrobial activity as compared with quinine itself on tested pathogenic bacterial strains. Ester quinine propionate was found to give the highest antibacterial activity among other derivatives, with a range inhibition zone from 9 to 23.5 mm to bacteria strains, compared to streptomycin with a range of inhibition zone from 8 to 12 mm. Further studies are needed to assess the bactericidal mechanisms of those derivative compounds.