bluuebunny/crossref_metadata_2025_split huggingface dataset:
Public perceptions of Lyme disease and climate change in southern Manitoba, Canada: Making a case for strategic decoupling of climate and health messages
Authors: Cameron Laura , Rocque Rhéa , Penner Kailey , Mauro Ian 
Published: July 2020

Abstract
Background: Despite scientific evidence that climate change has profound and far reaching implications for public health, translating this knowledge in a manner that supports citizen engagement, applied decision-making, and behavioural change can be challenging. This is especially true for complex vector-borne zoonotic diseases such as Lyme disease, a tick-borne disease which is increasing in range and impact across Canada and internationally in large part due to climate change. This research aims to better understand public risk perceptions of climate change and Lyme disease in order to increase engagement and motivate behavioural change.Methods: A focus group study involving 61 participants was conducted in three communities in the Canadian Prairie province of Manitoba in 2019. Focus groups were segmented by urban, rural, and urban-rural geographies, and between participants with high and low levels of self-reported concern regarding climate change. Results: Findings indicate a broad range of knowledge and risk perceptions on both climate change and Lyme disease, which seem to reflect the controversy and complexity of both issues in the larger public discourse. Participants in high climate concern groups were found to have greater climate change knowledge, higher perception of risk, and less scepticism than those in low concern groups. Participants outside of the urban centre were found to have more familiarity with ticks, Lyme disease, and preventative behaviours, identifying potential differential sources of resilience and vulnerability. Risk perceptions of climate change and Lyme disease were found to vary independently rather than correlate, meaning that high climate change risk perception did not necessarily indicate high Lyme disease risk perception and vice versa. Conclusions: This research contributes to the growing literature framing climate change as a public health issue, and suggests that in certain cases climate and health messages might be strategically decoupled when addressing climate skeptical audiences. A model showing the orthogonal relationship between Lyme disease and climate change perceptions is proposed, and implications for engagement on climate change health impacts are discussed.
Circular 3D Printing: Reprintable Polymers for Digital Light Processing Printing
Authors: Zhu Guangda , Hou Yi , Xu Jian , Zhao Ning 
Published: July 2020

Abstract
3D printing has become a disruptive technology and shown great potential for various practical applications. Specially, digital light processing (DLP) demonstrates advantages in high resolution and high efficiency. However, extensive production of infusible and insoluble thermosets in DLP printing causes serious resource waste and environmental problems after disposal. Herein, we report a reprintable linear polymer for circular DLP printing. Taking advantage of the dissolution of linear polymer in its monomer, printed objects can be recycled into liquid resin and reprinted via the same DLP. Polymerization kinetics and printing resolution of recycled resins, and mechanical properties of reprinted polymers retain identical as the original. Thermoplastic nature endows 3D objects with welding and reshaping property. Fully recyclable composites have also been successfully fabricated and sustainable usage of high-value fillers comes true. This strategy helps to address environmental issues arising from unprocessable thermosets and contributes to developing a circular materials economy.
Successful Outcome of Disseminated Candida Tropicalis Osteomyelitis on Remission Induction for Childhood Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia - Case Report
Authors: Xie Lichun , Long Qingling , Zhou Guichi , Liu Si-xi , Wen Feiqiu 
Published: July 2020

Abstract
Background: Invasive fungal infection (IFI) is one of the most challenging complications in children with acute lymphoblastic leukemia (ALL) treatment, but acute fungal osteomyelitis (OM) is rarely encountered. Case presentation: Here, we describe a case of Candida tropicalis osteomyelitis in a 10-year-old patient with Philadelphia chromosome (Ph)–positive ALL. He was on remission induction therapy at the time of neutropenia, and abscess developed in the right arm. The blood and bone cultures were positive for Candida tropicalis. Antibiotics and anti-fungal were given. A magnetic resonance of the arm revealed in intraosseous abscess, suggestive of OM. Surgical irrigation and debridement of the bone were performed immediately. The patient was effectively treated with antifungal therapy and ALL treatment. Now he full recovered into complete clinical remission but with sequelae visible by Magnetic Resonance Imaging (MRI). He took oral posaconazole for consolidation until disappearance of the lesion shadows on MRI and received subsequent cycles of chemotherapy in parallel. Conclusions: In the successful management of Ph-positive ALL, dasatinib the second-generation Abl–tyrosine kinase inhibitor is crucial. The recommended treatment for candida osteomyelitis in Ph-positive ALL patients are fungicidal agent combined with surgery and modification chemotherapy with dasatinib. Using combined modalities of treatment seem to be crucial in the successful management of Ph-positive ALL.
The Importance of Base Frame Fabrication in Microtia Reconstruction
Authors: Xu Zhicheng , Zhang Ruhong , Zhang Qun , Xu Feng , Li Datao , Li Yiyuan 
Published: July 2020

Abstract
Background The base frame provides stable support for the helix, antihelix, and tragus-antitragus complex in microtia reconstruction, and this support is vital to attain a highly defined outline for a reconstructed auricle. The success of base frame sculpting depends on appropriate treatment of the cartilage, mainly the sixth and seventh costal cartilages, which may have different characteristics. The aim of this study is to demonstrate the relevant details for base frame fabrication in various scenarios.Methods This study included 352 patients with microtia who underwent autologous auricular reconstruction between 2016 and 2019. Concerning the different sizes and characteristics of the costal cartilage used for base frame reconstruction, we describe related methods for fabrication and introduce corresponding strategies for proper management.Results Relevant techniques in base frame fabrication have been shown to produce favorable results. The elaborately sculpted base frame establishes a stable foundation and natural protrusion of the helix, antihelix and tragus-antitragus complex. The base frame contributes to the integrity of a harmonious appearance of the reconstructed ear.Conclusions The elaborate design and appropriate utilization of costal cartilage for base frame sculpting is one of the most significant and fundamental processes in microtia reconstruction. It contributes to achieving a clearly defined outline of the auricle with harmonious integrity, which is as important as the other projected subunits.
Percutaneous endoscopic treatment of benign and malignant renal pelvis carcinoma: A single-center experience
Authors: Zhang Xin , Han Wu Xiu , Li Sheng Yan , Chen Hao Yuan , Tang Zhe Yu , Zhang Peng , Li Tao , Wang Yuan Si 
Published: July 2020

Abstract
Background Percutaneous nephrolithotomy (PCNL) is a safe and efficient treatment for intro-renal diseases, most of which are calculus disease. In this study, we carried out percutaneous endoscopic nephron-sparing ablation for renal carcinoma in carefully selected patients. Our aim was to evaluate whether percutaneous endoscopic nephron-sparing operation was feasible for patients with renal cell carcinoma.Methods A total of 15 patients with renal pelvis carcinoma were treated with laser evaporation under percutaneous endoscopy between January 2015 and September 2019 ( group I ). Another 13 patients who received standard radical nephroureterectomy were recruited as the control group (group II). We recorded demographic data of the patients, the indication for surgery, tumor pathological grade, size and side of tumor, and the intraoperative and postoperative outcome, including the duration of surgery, length of hospital stay, and complication rate, as well as progression-free survival (PFS).Results In both groups, all of the patients received flexible ureteroscopy. In group I, 14 patients had transitional renal cell carcinoma (UCC), four had pathological grade I, nine had grade II, and one had hemangiopericytoma. In group II, all patients had UCC, five had pathological grade I, and eight had grade II. In group I, the mean operation time was 118 min (65–236 min), the mean blood loss was 110 ml (55–220 ml), and the mean hospital stay was 9 days (7–12 days). During follow-up, two patients died and two had recurrence; among them, one had systematic bone metastasis. The PFS rate was 66.7% (10/15). In group II, the mean operation time was 265 min (185–436 min), the mean blood loss was 133 ml (85–240 ml), and the mean hospital stay was 13 days (9–16 days). During the follow-up, two patients died and there was no local or systematic metastasis. The PFS rate was 84.6% (11/13). There was no significant difference in blood loss between the groups. However, the operation time and mean hospital stay were significantly shorter in group I compared with that in group II ( P < 0.05). But the PFS rate was significantly higher in group II than in group I (P < 0.05).Conclusions This study shows that laser evaporation under percutaneous endoscopy for renal pelvis carcinoma is a safe, effective, and technically feasible procedure for treating benign and malignant renal pelvis carcinoma.
Finite Element Analysis of Different Percutaneous Fixation Strategies Used for the Treatment of Tile C1.2 Pelvic Fracture
Authors: Xu changqing , Zhu wanbo , Liu lei , Yang jiazhao , Fang shiyuan 
Published: July 2020

Abstract
Objectives

We evaluated the biomechanical outcomes of 9 different percutaneous fixation strategies used for the fixation of Tile C1.2 pelvic fracture. This may help surgeons choose the optimal therapy for the unstable pelvic fracture.
Methods

Tile C1.2 pelvic fractures and implant models were constructed using finite element analysis (FEA) software. Models were assembled for different fracture fixation types. After meshing the models’ elements, we used Abaqus software to perform the FEA. Values of the von Mises Stress and model displacement were used to capture the mechanical factors.
Results

The FEA shows that under axial loading and external rotational loading of 500 N, the combination of an S1 screw and the Infix system provide strong stability, and that an increased number of screws to fix the anterior pelvic ring increased stability.
Conclusion

This study indicates that a 3-screw-Infix system on the healthy side, plus an S1 sacroiliac screw improves stability of the Tile C1.2 fracture.
Fetal double aortic arch: prenatal sonographic and postnatal computed tomography angiography features, associated abnormalities and clinical outcomes
Authors: Guo Qiao , Kong Yifan , Zeng Shi , Zhou Jiawei , Wang Xiaofang , Shang Quanliang , Zhou Jia , Yuan Hongxia , Wang Ling , Tong Lili , Yi Aijiao , Zhou Qichang 
Published: July 2020

Abstract
Background: Fetal double aortic arch (DAA) malformation is a rare congenital heart disease. There is a lack of large sample on comparative study of prenatal ultrasound diagnosis with postnatal computed tomography angiography (CTA) diagnosis, surgery, and autopsy results.Methods: A retrospective cohort study was carried out on cases of fetal DAA that underwent a comprehensive ultrasound examination and were seen during a six-year period at seven tertiary referral centers.Results: A total of 36 cases out of 40 prenatally diagnosed DAA fetuses were confirmed by postnatal diagnosis (fetal autopsy, CTA, and surgery). In this cohort of 36 confirmed cases, 24 (67%) were isolated anomalies, while 12 (33%) were associated with intracardiac or extracardiac anomalies, and 2 (6%) had a 22q11.2 chromosome deletion. There were 9 cases of pregnancy termination with a fetal autopsy. Among the remaining 27 live births, 16 (59%) were asymptomatic and 11 (41%) received surgical treatment due to tracheal or esophageal compression symptoms, all with satisfactory outcomes. Prenatal echocardiography showed that DAA was mainly characterized by a bifurcation of the ascending aorta into the right and left aortic arch and the formation of a complete O-shaped vascular ring around the trachea on the three-vessel tracheal view. A variant in the aortic arch branching pattern was found for the first time. The airway obstruction, branching pattern and atretic arch of DAA were clearly shown by postnatal CTA.Conclusions: Fetal DAA has unique features on prenatal echocardiography and postnatal CTA, and steps and tips for systematic prenatal examination are required. The clinical outcomes of isolated DAA are favorable, even if surgery is performed due to symptoms. Determining whether other malformations or chromosomal anomalies exist is crucial for prognosis evaluation and prenatal decision-making.
PlatCOVID: A Novel Web Tool to Analyze, Curate and Share COVID-19 Literature
Authors: Brandão Lucas André Cavalcanti , Agrelli Almerinda , Bernardo Lucas , Paparella Francesco , Moura Ronald , Crovella Sergio 
Published: July 2020

Abstract
BackgroundIn the attempt to face the COVID-19 pandemic, the global scientific community has been expending great efforts to produce useful and reliable data aiming to help patients, physicians and guiding public health policies. A huge amount of information is being released every week, making impossible for a single person (or even for a research group) to read everything and get constantly updated on the scientific literature concerning COVID-19 and its etiological agent, SARS-CoV-2. Therefore, we developed PlatCOVID (www.platcovid.com), a Web platform designed to analyze, cluster, classify and discuss COVID-19 literature available on LitCovid (NCBI). ResultsPlatCOVID has been created as a novel COVID-19 hub able to add features of text mining and syntax analyses methods, such as word and sentence atomization and tokenization, clusterization and classification. The main division of the literature comprehends five categories: 1) Diagnosis; 2) Epidemiology; 3) Clinical, Signs & Symptoms; 4) Transmission; and 5) Treatment & Prevention. Consequently, it is possible to reduce the amount of text to be read with minimal loss of information, identifying target subjects by mining as new insights arise, enhancing data analysis efficiency. PlatCOVID has been designed with central panels (Gene, Drug and Tissue panels) to easily gather and share with the scientific community important COVID-19 information.ConclusionsAlthough most of the text mining and syntax analysis is made by using automated computing processes, the final results must to be humanly curated. With this in mind, PlatCOVID allows researchers to be part of our effort to curate, analyze, discuss and rate each matter of interest (helpus.platcovid.com). We welcome user feedback for further enhancement.
Household knowledge, perceptions and practices of mosquito larval source management for malaria prevention and control in Mwanza district, Malawi: A cross-sectional study
Authors: Kamndaya Mphatso , Mfipa Dumisani , Lungu Kingsley 
Published: July 2020

Abstract
Background
Mosquito larval source management (LSM) is a key outdoor malaria vector control strategy in rural communities in sub-Saharan Africa. Knowledge of this strategy is important for optimal design and implementation of effective malaria control interventions in this region. This study assessed household knowledge, perceptions and practices of mosquito LSM methods (draining stagnant water, larviciding, clearing grass/bushes and clean environment).
Methods
A cross-sectional design was used whereby 479 households were selected using two-stage sampling in Mwanza district, Malawi. A household questionnaire was administered to the head of the house. Respondents were asked questions on knowledge, perceptions and practices of mosquito LSM methods. Multivariable logistic regression model was used to identify factors associated with high-level knowledge of mosquito LSM methods.
Results
Majority of the respondents (64.3%) had high-level knowledge of mosquito LSM methods. Specifically, 63.7% (200/314) had positive-perceptions about draining stagnant water whereas 95.3% (223/234) practiced clean environment for malaria control and 5.2% had knowledge about larviciding. Compared to respondents with primary education, those with secondary education were 3.04 times more likely to have high-level knowledge of mosquito LSM methods (AOR = 3.04, 95% CI 1.30–7.14), whereas those with no education were 0.40 times less likely to have high-level knowledge of mosquito LSM methods (AOR = 0.40, 95% CI 0.24–0.67). Respondents living in mudwalled households were 0.54 times less likely to have high-level knowledge of mosquito LSM methods as compared with those living in brickwalled households (AOR = 0.54, 95% CI 0.32–0.92).
Conclusions
Larviciding was the least mentioned method whereas positive-perceptions for larviciding and clearing grass/bushes were low. Targeted health promotion interventions may improve knowledge, perceptions and practices of mosquito LSM methods in communities.
Student Perspective Of Classroom And Distance Learning Method During Covid-19 Pandemic In The Undergraduate Dental Study Program
Authors: Amir Lisa , Tanti Ira , Maharani Diah Ayu , Wimardhani Yuniardini , Julia Vera , Sulijaya Benso , Puspitawati Ria 
Published: July 2020

Abstract
Background: The COVID-19 pandemic has become a global health issue and has had a major impact on education. Consequently, half way through the even semester of the academic year 2019/2020, learning methods were delivered through distance learning. This study aimed to evaluate the s tudent perspective of distance learning compared to the classroom learning in the undergraduate dentistry study program at the Faculty of Dentistry Universitas Indonesia. Methods: An online questionnaire was sent to dental students of Universitas Indonesia at the end of the semester. Three hundred and one undergraduate dental students participated in the study, with 83.4% response rate. The internal consistency reliability questionnaire was measured by Cronbach’s alpha. Logistic regression analyses were conducted to identify factors associated with the students’ preference towards distance learning. Results: Duration of study influenced student preference on distance learning (DL). Significantly higher number of first-year students preferred DL compared to their seniors (p<0.001). While neither gender nor Grade Point Average (GPA) score influenced student preference on DL. Students agreed that DL was suitable for lectures and examination while they preferred classroom learning (CL) for group discussion, as DL resulted in more difficult communication and gave less learning satisfaction. Only 44.5% students preferred DL over CL, although they agreed that DL gave a more efficient learning method (52.6%), it provided more time to study (87.9%) and to review study materials (87.3%). The Cronbach alpha of the questionnaire was 0.880. The logistic regression analysis showed that efficiency has the highest odds ratio in relation to preference towards distance learning. Challenges during distance learning included external factors such as unstable internet connection, extra financial burden for the internet quota and internal factors such as time management and difficulty to focus while learning online for a longer period of time. Conclusion: Despite some challenges, dental students could adapt to the new learning methods of full DL and the majorities agreed blended learning that combined classroom and distance learning can be implemented henceforth. This current COVID-19 pandemic, changes not only the utilization of technology in education but the pedagogy strategies in the future.
Optimization of membrane dispersion ethanol precipitation process with a set of temperature control improved equipment
Authors: Pan Jingjing , Tai Yanni , Qu Haibin , Gong Xingchu 
Published: July 2020

Abstract
Background
Ethanol precipitation is an important separation and purification process in the traditional Chinese medicine (TCM) industry. However, ethanol precipitation process suffers from loss of active ingredients, low batch-to-batch consistency of supernatant composition, and long standing time. These problems are mainly caused by low efficient equipment and imperfect control strategy.
Methods
In the present study, a membrane dispersion ethanol precipitation device which can achieve rapid cooling was developed for Astragali radix ethanol precipitation. Ethanol precipitation process was optimized according to Quality by design concept. To identify critical material attributes (CMAs), ten batches of Astragali radix was used to prepare concentrates. Definitive screening design was used to investigate the relationships among critical process parameters, CMAs, and process critical quality attributes (CQAs).
Results
Calycosin-7-O-β-D-glucoside content, the sucrose content, and the electrical conductivity were found to be CMAs after the correlation analysis and stepwise regression modelling. Quadratic models were developed and design space was calculated according to the probability of attaining process CQA standards. A material quality control strategy was proposed. High quality and low quality Astragali radix concentrates can be discriminated by the inequalities. Low quality Astragali radix concentrates should not be released for ethanol precipitation process directly. Verification experiment results indicated accurate models and reliable design space.
Conclusions
The temperature control method and control strategy in this study are effective and promising for ethanol precipitation process of other TCMs or foods.
The effect of surgical decompression on symptoms in peroneal nerve entrapment neuropathy
Authors: Ercan Serdar , Ataizi Zeki Serdar 
Published: July 2020

Abstract
Objective

CPN entrapment neuropathy is a form of lower extremity entrapment, most commonly seen at the level of the fibula head, often presenting with foot drop findings. We aimed to investigate whether decompressive surgical intervention contributes to neuropathy clinic.
Materials and methods

Patients who were admitted to our clinic with a preliminary diagnosis of peroneal entrapment neuropathy and underwent surgical intervention were included in the study. Preoperative and postoperative motor functions and pain were evaluated.
Results

Postoperative significant changes in pain and muscle strength scores were observed. A significant decrease was observed in the postoperative VAS score.
Conclusion

Surgical decompression is the right option for the recovery of motor function in the treatment of peroneal nerve entrapment neuropathy.