bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chylorhabditis epuraeae n. gen., n. sp. (Rhabditida: Rhabditidae) isolated from Epuraea (Haptoncus) ocularis Fairmaire collected from sap on the bark of Ulmus parvifolia Jacq. in Kyoto, Japan
Authors: Kanzaki Natsumi , Hamaguchi Keiko , Takeuchi-Kaneko Yuko 
Published: October 2020

Summary
A new rhabditid entomophilic nematode was isolated from adult Epuraea (Haptoncus) ocularis collected from brown to light brown sap on the trunk of Ulmus parvifolia in Kyoto, Japan. The typological characters of the species, anteriorly opened peloderan bursa with nine bursal rays with the first, fifth, and eighth pairs directed dorsally, very long and two-part spicule with broad tip, and elongate conical female tail, do not fit the current nominal rhabditid genera. While phylogenetic analyses based on the near-full-length small subunit (18S) ribosomal RNA sequence tentatively suggest that the species is the sister of Buetschlinema, the typological and biological characters of the new species clearly differ from that genus, and so a new species is described herein as Chylorhabditis epuraeae n. gen., n. sp.
Effects of Meloidogyne incognita, Pectobacterium betavasculorum and Rhizoctonia solani interactions on growth, physiological and biochemical changes of beetroot
Authors: Khan Manzoor R. , Siddiqui Zaki A. 
Published: October 2020

Abstract
Effect of Meloidogyne incognita, Pectobacterium betavasculorum and Rhizoctonia solani alone, pre, post and simultaneous inoculations to find out role of each pathogen on growth, chlorophyll and carotenoid, superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), ascorbate peroxidase (APX), glutathione peroxidase (GPX), glutathione reductase (GR) activities and proline, H2O2 and malondialdehyde (MDA) of beetroot (Beta vulgaris L). Inoculation of plants with M. incognita / P. betavasculorum or R. solani reduced plant growth (root dry weight) (42.0%), chlorophyll (24.2%) and carotenoid (47.7%) while inoculation of pathogens under study resulted in increased activities of antioxidant enzymes, proline, H2O2 and MDA. Combined inoculation of pathogens under study resulted in greater reduction of plant growth (74.9%), chlorophyll (55.3%) and carotenoid (83.7%) than individual pathogen. Greatest reduction in plant growth, chlorophyll and carotenoid and maximum activities of antioxidant enzymes, proline, H2O2 and MDA were observed when M. incognita was inoculated 20 days prior to P. betavasculorum plus R. solani. P. betavasculorum and R. solani reduced galling and nematode multiplication but maximum reduction in galling (82.8%) and nematode multiplication (82.7%) was observed when P. betavasculorum plus R. solani were inoculated prior to nematodes. Necrosis soft rot and root rot indices by P. betavasculorum and R. solani were 3 respectively. Disease indices were 5 when two or more pathogens were inoculated together. Prior inoculation of M. incognita predisposed beetroots to P. betavasculorum and R. solani and aggravates the disease.
Plato in Bad Company? Plato’s Republic (588b–589b) in the Nag Hammadi Collection: A Re-Examination of Its Background
Authors: Ashwin-Siejkowski Piotr 
Published: October 2020

Abstract
The Coptic translation of a passage from Plato’s Republic (588b–589b) found in the sixth Codex of the Nag Hammadi collection has received very limited academic attention in comparison with other tractates from the same Codex. This paper argues that placing this passage within Clement of Alexandria’s polemic with Christian Platonists Carpocrates and his son Epiphanes, may provide a fresh and insightful comment on the use of Republic, with its anthropology and ethics among various second-century Christian teachers. This passage allegorizes various passions within the human soul and warns against injustice. According to Clement of Alexandria the subject of justice, or righteousness, was one of the subjects which attracted the attention of Epiphanes. I propose that the origin of the Coptic passage goes back to the second-century effort to assimilate Platonic ideas about the human soul into Christian ethics. Although various apologists accused Carpocrates and Epiphanes of sexual immorality, I focus on the possibility that Christians with Platonic tendencies were exploring the nature and power of human passions and considering how they could be controlled. The place of the excerpt in the Nag Hammadi collection is not coincidental but goes along other mythological and didactic treatises within.
Gnostic Myth in Manichaeism?
Authors: BeDuhn Jason 
Published: October 2020

Abstract
The widespread assumption that the Manichaean religion depended on some antecedent form of “Gnosticism” requires critical assessment. Manichaean myth shows no distinctive points of connection to theogonic, cosmogonic, or cosmological details in those narratives typically classed as belonging to “gnostic” sects. Striking narrative parallels between Manichaean and “gnostic” accounts of anthropogenesis, therefore, are anomalous, and may be best explained by independent dependence on a common source, rather than direct contact between Manichaeans and gnostic groups. A variety of evidence suggests this common source to be Jewish demiurgical traditions inspired by a desire to insulate God from responsibility for flaws in human nature. In light of this analysis, Manichaean continuity directly with Jewish narrative traditions, without “gnostic” mediation, appears to be more fundamental to the religion’s core myth than previously supposed.
Regional Differences in the Human Toll from Tornadoes: A New Look at an Old Idea
Authors: Biddle Matthew D. , Brown Ryan P. , Doswell Charles A. , Legates David R. 
Published: October 2020

AbstractPreviously published claims of large regional (northern vs southern states) differences in risks of fatality associated with tornadoes in the United States are reexamined. This new study extends earlier claims to include 1) data from a much longer time frame, 2) injuries as well as fatalities, and 3) more precise estimates of meteorological features of tornado events (specifically, a precise calculation of daytime vs nighttime and pathlength). The current study also includes formal mediation analyses involving variables that might explain regional differences. Results indicate that significant increases in the risk of fatality and injury do occur in southern states as compared with northern states. Mediation models show that these regional differences remain significant when meteorological factors of nocturnal occurrence and pathlength are included. Thus, these meteorological factors cannot explain regional differences in risk of fatality and injury, a failure that is unlikely to reflect a lack of data or a lack of precision in the measurement of potential mediators.
Long-Term Clinical Follow-Up of Patients With Chronic Rhinosinusitis
Authors: Thunberg Ulrica , Saber Amanj , Söderquist Bo , Hugosson Svante 
Published: October 2020

Objective: This study comprised a long-term follow-up of a cohort of patients with chronic rhinosinusitis (CRS) regarding clinical features and symptomatology. Methods: Data from 42 patients with CRS were available from a previous study. Forty of these patients were alive and were contacted for inclusion after approximately 10 years. Patients completed a questionnaire about disease and symptoms, and underwent a clinical examination. Results: Thirty-four patients (85%) responded and could be included and evaluated. For the participants in this follow-up study median length of time between initial inclusion (C1) and follow-up (C2) was 11 years (range: 8-15). In some patients the CRS shifted phenotype over time, from CRS with nasal polyposis to CRS without nasal polyposis or vice versa. The median total visual analogue score for combined sinonasal symptoms for all patients was statistically significantly reduced at follow-up. For individual patients, scores for nasal congestion, nasal discharge, facial pressure, and hyposmia were also statistically significantly reduced. The most frequently reported symptom-relieving treatments were nasal steroids and saline rinsing of the nose. Self-reported general quality of life was statistically significantly improved at C2 compared to C1. Conclusion: At long-term follow-up, symptoms were generally reduced and patients reported an improved quality of life. Patients can be given hope for eventual symptom relief. CRS is a chronic condition that seems to harbor the ability to alter its phenotype after several years. Topical corticosteroids and saline rinsing of the nose should be emphasized, since patients consider these treatments to be of high value.
Classification and treatment of endothermal heat-induced thrombosis: Recommendations from the American Venous Forum and the Society for Vascular Surgery This Practice Guidelines document has been co-published in Phlebology [DOI: 10.1177/0268355520953759] and Journal of Vascular Surgery: Venous and Lymphatic Disorders [DOI: 10.1016/j.jvsv.2020.06.008]. The publications are identical except for minor stylistic and spelling differences in keeping with each journal’s style. The contribution has been published under a Attribution-Non Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0), (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Authors: Kabnick Lowell S. , Sadek Mikel , Bjarnason Haraldur , Coleman Dawn M. , Dillavou Ellen D. , Hingorani Anil P. , Lal Brajesh K. , Lawrence Peter F. , Malgor Rafael , Puggioni Alessandra 
Published: October 2020

The American Venous Forum (AVF) and the Society for Vascular Surgery set forth these guidelines for the management of endothermal heat-induced thrombosis (EHIT). The guidelines serve to compile the body of literature on EHIT and to put forth evidence-based recommendations. The guidelines are divided into the following categories: classification of EHIT, risk factors and prevention, and treatment of EHIT. One major feature is to standardize the reporting under one classification system. The Kabnick and Lawrence classification systems are now combined into the AVF EHIT classification system. The novel classification system affords standardization in reporting but also allows continued combined evaluation with the current body of literature. Recommendations codify the use of duplex ultrasound for the diagnosis of EHIT. Risk factor assessments and methods of prevention including mechanical prophylaxis, chemical prophylaxis, and ablation distance are discussed. Treatment guidelines are tailored to the AVF EHIT class (ie, I, II, III, IV). Reference is made to the use of surveillance, antiplatelet therapy, and anticoagulants as deemed indicated, and the recommendations incorporate the use of the novel direct oral anticoagulants. Last, EHIT management as it relates to the great and small saphenous veins is discussed.
Scabies: Diagnostic and Therapeutic Update
Authors: Richards Robert N. 
Published: October 2020

Background Scabies is globally ubiquitous and is a significant health issue for institutions, the economically disenfranchised, resource-poor areas, and for those with weakened immune systems. Topicals are usually effective, but are cumbersome and expensive to use in large populations and for those nonadherent to topicals. Oral ivermectin became available in Canada for the off-label treatment of scabies in the fall 2018. Objectives To review the diagnosis and management of scabies. Dose schedules and concomitant management measures are outlined for scabies simplex and for crusted scabies. Ivermectin use is outlined. Methods Medline, colleague discussions, practice review, and experience from managing scabies in institutions. Results Oral ivermectin is safe, easier to use, cheaper, more effective, and more economical than topicals in widespread institutional scabies, for those nonadherent to topicals, and in crusted scabies. Conclusions Oral ivermectin is the treatment of choice in large populations, the nonadherent, and for crusted scabies. Oral ivermectin is produced by Merck Canada as Stromectol 3 mg. The treatment dose for noncrusted scabies is 200 µg/kg, taken in a single dose with food. For example, 15 mg (5 tablets) for a 70 kg person. Retreat in 10-14 days to enhance effectiveness, and perhaps to reduce scabicide resistance.
Trends in alcohol consumption among older adults in Denmark in the 21st century
Authors: Jensen Heidi Amalie Rosendahl , Bloomfield Kim , Lau Cathrine Juel , Ekholm Ola 
Published: October 2020

Background: Previous studies have indicated that the alcohol consumption among older Danish individuals has increased during the last three decades of the 20th century. However, the research is limited and, hence, the aim of the present article is to describe the trends and peculiarities in the development of the present situation in older people’s drinking patterns in Denmark. Methods: Data were obtained from the Danish Health and Morbidity Survey (2005) and the Danish National Health Survey (2010, 2013, and 2017). Data used in this study were collected via self-administered questionnaires from random samples of the adult (≥ 16 years) Danish population. Response rates varied between 50.8% (2005) and 59.5% (2010). Drinking patterns are described using the following indicators: alcohol consumption during the past 12 months; alcohol consumption at least two days a week; mean number of standard drinks consumed in a typical week and heavy episodic drinking (at least monthly). Results are presented as percentages or means. Results: The prevalence of overall 12-month alcohol use in all individuals aged 60 years or older has slightly increased between 2010 (83.9%) and 2017 (85.2%). On the other hand, the prevalence of consuming alcohol at least twice a week has overall decreased slightly between 2010 (54.0%) and 2017 (52.0%) in the same age group. A decrease was also observed in the mean number of standard drinks consumed in a typical week, from 8.3 in 2010 to 7.0 in 2017. Additionally, the prevalence of consuming at least five standard drinks on one occasion at least monthly decreased markedly from 24.8% in 2005 to 14.8% in 2013 (the prevalence remained stable between 2013 and 2017). The trends in prevalence of various alcohol indicators varied by sex and age. Conclusions: The findings of this study suggest an overall decline in alcohol consumption among older Danes in the study period. The continuation of this trend will be the subject of future studies.
Cavitation of a Submerged Jet at the Spherical Valve Plate/Cylinder Block Interface for Axial Piston Pump
Authors: Zhao Bin , Guo Weiwei , Quan Long 
Published: October 2020

AbstractThe spherical valve plate/cylinder block pair has the advantages of strong overturning resistance and large bearing area. However, the configurations of the unloading and pre-boosting triangular grooves on the spherical valve plate are different from those in the planar valve plate, resulting in special cavitation phenomenon on the spherical port plate pair. In order to study cavitation characteristics of spherical port plate pair, a dynamic CFD model of the piston pump including turbulence model, cavitation model and fluid compressibility is established. A detailed UDF compilation scheme is provided for modelling of the micron-sized spherical oil film mesh, which makes up for the lack of research on the meshing of the spherical oil film. In this paper, using CFD simulation tools, from the perspectives of pressure field, velocity field and gas volume fraction change, a detailed analysis of the transient evolution of the submerged cavitation jet in a axial piston pump with spherical valve plate is carried out. The study indicates the movement direction of the cavitation cloud cluster through the cloud image and the velocity vector direction of the observation point. The sharp decrease of velocity and gas volume fraction indicates the collapse phenomenon of bubbles on the part wall surface. These discoveries verify the special erosion effect in case of the spherical valve plate/cylinder block pair. The submerged cavitation jet generated by the unloading triangular grooves distributed on the spherical valve plate not only cause denudation of the inner wall surface of the valve plate, but also cause strong impact and denudation on the lower surface of the cylinder body. Finally, the direction of the unloading triangular groove was modified to extend the distance between it and the wall surface which can effectively alleviate the erosion effect.
Penile fracture in a Peyronie’s disease patient: a case report
Authors: Hidayatullah Nur , Kholis Khoirul , Palinrungi Muhammad Asykar , Syahrir Syakri , Syarif Syarif , Faruk Muhammad 
Published: October 2020

Abstract
Background
Penile curvature in men with Peyronie’s disease (PD)—caused by tunica anchoring plaques with loss of focal fiber elasticity—theoretically increases the risk of penile fracture during sexual activity. Penile fracture is the result of tearing of the tunica albuginea of one or both corpora cavernosa, usually during sexual intercourse, and is among the most serious urological emergencies. Generally, a patient presented to a surgical emergency within 48 h of injury can be handled successfully with minimum complications. Immediate surgical treatment is the current standard of care and has a relatively low risk of late complications.

Case presentation
We present a case of penile fracture in a male with a history of PD referred to the emergency department with severe pain. Clinical history assessment and physical examination revealed a penile fracture with underlying PD. He underwent emergency surgical exploration via subcoronal incision. Penile plication was not necessary for our case because the angulation of the penis was less than 15° after examination of artificial erection.

Conclusion
Penile fracture in a patient with underlying PD is a rare urological emergency that should be treated surgically with fracture repair as early as possible. Penile plication might be necessary in severe cases (angulation > 60°).
Views of advanced cancer patients, families, and oncologists on initiating and engaging in advance care planning: a qualitative study
Authors: Toguri J. T. , Grant-Nunn L. , Urquhart R. 
Published: October 2020

Abstract
Background
Advance care planning (ACP) is a process by which patients reflect upon their goals, values and beliefs to allow them to make decisions about their future medical treatment that align with their goals and values, improving patient-centered care. Despite this, ACP is underutilized and is reported as one of the most difficult processes of oncology. We sought to: 1) explore patients’ and families’ understanding, experience and reflections on ACP, as well as what they need from their physicians during the process; 2) explore physicians’ views of ACP, including their experiences with initiating ACP and views on ACP training.

Methods
This was a qualitative descriptive study in Nova Scotia, Canada with oncologists, advanced cancer out-patients and their family members. Semi-structured interviews with advanced cancer out-patients and their family members (n = 4 patients, 4 family members) and oncologists (n = 10) were conducted; each participant was recruited separately. Data were analyzed using constant comparative analysis, which entailed coding, categorizing, and identifying themes recurrent across the datasets.

Results
Themes were identified from the patient / family and oncologist groups, four and five respectively. Themes from patients / families included: 1) positive attitudes towards ACP; 2) healthcare professionals (HCPs) lack an understanding of patients’ and families’ informational needs during the ACP process; 3) limited access to services and supports; and 4) poor communication between HCPs. Themes from oncologists included: 1) initiation of ACP discussions; 2) navigating patient-family dynamics; 3) limited formal training in ACP; 4) ACP requires a team approach; and 5) lack of coordinated systems hinders ACP.

Conclusions
Stakeholders believe ACP for advanced cancer patients is important. Patients and families desire earlier and more in-depth discussion of ACP, additional services and supports, and improved communication between their HCPs. In the absence of formal training or guidance, oncologists have used clinical acumen to initiate ACP and a collaborative healthcare team approach.
Left atrial strain and diastolic function abnormalities in obese and type 2 diabetic adolescents and young adults
Authors: Steele Jeremy M. , Urbina Elaine M. , Mazur Wojciech M. , Khoury Philip R. , Nagueh Sherif F. , Tretter Justin T. , Alsaied Tarek 
Published: October 2020

Abstract
Background
Adults with obesity and type 2 diabetes mellitus (T2DM) related to obesity are at increased risk of heart failure with preserved ejection fraction (HFpEF). Whether left ventricular (LV) diastolic function abnormalities related to obesity and T2DM start in adolescence and early adulthood is unknown. We non-invasively evaluated the differences seen in LV diastolic and left atrial (LA) function in adolescents and young adults with obesity and T2DM.

Methods
We analyzed echocardiographic measures of LV diastolic function in patients with structurally normal hearts which were divided into 3 groups (normal weight, obese, and T2DM). Spectral and tissue Doppler and 2-D speckle tracking measurements of diastolic function were obtained. Logistic regression was performed to compare the prevalence of abnormalities in diastolic function based on the worst 25th percentile for each measure to determine the prevalence of diastolic and LA function abnormalities in obese and T2DM patients.

Results
331 teenagers and young adults (median age 22.1 years) were analyzed (101 normal weight, 114 obese, 116 T2DM). Obese and T2DM group had lower E/A and higher E/e′. Obese and T2DM patients had significantly lower atrial reservoir, conduit, and booster strain and worse reservoir and conduit strain rate compared to normal patients (p < 0.001 for all measures). All patients had normal LA volumes. On multivariable analysis, conduit strain and reservoir and conduit strain rate were independently associated with having below the 25th percentile e′. Conduit strain rate was independently associated with having below the 25th percentile for mitral E/A ratio on multivariable analysis.

Conclusions
Abnormal indices of LV diastolic function are detected in adolescents and young adults with obesity and T2DM. LA function and strain analysis were able to detect evidence of decreased reservoir, conduit, and booster strain in these patients although LA volume was normal. The use of LA function strain may increase our ability to detect early diastolic function abnormalities in this population.