bluuebunny/crossref_metadata_2025_split huggingface dataset:
International recommendations for an effective control of head louse infestations
Authors: Mumcuoglu Kosta Y. , Pollack Richard J. , Reed David L. , Barker Stephen C. , Gordon Shirley , Toloza Ariel C. , Picollo Maria I. , Taylan‐Ozkan Aysegul , Chosidow Olivier , Habedank Birgit , Ibarra Joanna , Meinking Terri L. , Vander Stichele Robert H. 
Published: August 2020

AbstractHead louse infestations continue to be a concern of public health in most countries, including the most developed ones. The present recommendations are intended to inform and stress the role and impact of the different authorities, institutions, industry, and the public in the control of head lice in order to reduce the prevalence of this parasite. We encourage health authorities to pursue more effective methods to correctly identify such infestations, and evaluate existing and new pediculicides, medical devices, louse repellents, and louse‐ and nit‐removal remedies. Pediculicides and medical devices must have verifiable claims in the instructions for use and should be tested periodically to document current levels of resistance by lice to the active ingredients and to the formulated products. Where the prevalence of lice is claimed to be epidemic, children should be periodically evaluated objectively to document the actual level of prevalence. Continuing education for health providers and the general population promises to correct misinformation regarding the biology, prevention, and management of lice. Parents should regularly inspect their children for head lice and treat as necessary. Health authorities are encouraged to eliminate policies and practices that rely upon school exclusion as a means to reduce incidence and prevalence, e.g., the ‘no‐nit’ policy which lacks scientific justification, and are counterproductive to the health and welfare of children.
Same‐sex parents facing parenting standards. First results from three longitudinal studies
Authors: Geay Bertrand , Humeau Pierig , Spruyt Emilie 
Published: August 2020

AbstractHow do same‐sex parents take on the “job” of parenting and the institutional norms that define it during the first months of the child's life? What are the proximities and differences between same‐sex parents and heterosexual parents in matters of eating habits, hygiene, emotional regulation, and play habits? This paper answers these questions by using a systematic comparison of data provided by the French Longitudinal Study of Children (Étude Longitudinale Française depuis l'Enfance or ELFE) and the DEVHOM project. We first underline the fact that the habits of gay and lesbian families are close to those of the families belonging to social groups which they most often originate from: educated middle and upper classes. However, they differ on a greater sensitivity to breastfeeding norms and a greater concern for some aspects of their children's development. We offer three hypotheses to explain this difference: primary socialisation, specific forms of family organisation and a greater normative pressure felt by homosexual couples.
Experimental and numerical investigations of an oxygen single‐bubble shrinkage in a borosilicate glass‐forming liquid doped with cerium oxide
Authors: Pereira Luiz , Kloužek Jaroslav , Vernerová Miroslava , Laplace Annabelle , Pigeonneau Franck 
Published: August 2020

AbstractThe shrinkage of an oxygen single‐bubble is investigated in a cerium‐doped borosilicate glass melt at 1150°C. Nine glass samples are synthesized and investigated, utilizing three different amounts of Ce2O3 and three different redox ratios (Ce‐(III)/Cetotal). Employing in‐situ observation, the single‐bubble behavior is recorded with a camera. For each glass melt, five experiments are performed with different initial bubble radii. The shrinkage rate () depends strongly on the cerium content as well as the redox ratio. Numerical calculations are also conducted to support the understanding of the bubble shrinkage mechanism in the given cases. The model adequately estimates the experimental data for several cases, and an explanation is proposed for the cases, in which it does not. Moreover, we demonstrate, physically and mathematically, the influence of the initial radius of the bubble on the mass transfer between the rising bubble and the melt. We confirm the utilization of the “modified Péclet number,” which is a dimensionless number that takes into consideration the influence of multivalent elements on mass transfer. Finally, we master the bubble shrinkage behavior by normalizing the experimental data employing a characteristic time for the mass transfer (τ).
Supportive treatment following peri‐implantitis surgery: An RCT using titanium curettes or chitosan brushes
Authors: Koldsland Odd Carsten , Aass Anne Merete 
Published: August 2020

AbstractAimsThe aim of this randomized controlled trial was to assess the effect of two maintenance programmes when treatments were performed every third month from six to 18 months following surgical treatment of peri‐implantitis.Materials and methodsAt the 6‐month post‐surgical evaluation, 44 subjects were randomized into groups receiving supportive peri‐implant treatment either by the use of titanium curettes or chitosan brushes at implants registered with BoP and PPD >3 mm. Follow‐up examinations and supportive therapy were performed 6, 9, 12, 15 and 18 months post‐surgically. Clinical and radiographic assessments were made.ResultsThe percentage of implants registered with inflammation was high at the 6‐month baseline examination (>80% bleeding on probing in both test and control group) and remained high throughout the observation period. Similar observations were made for all clinical parameters, and no significant difference was found between test and control groups.ConclusionsIn the present study, no statistical significant difference was found when supportive peri‐implant treatment was performed with either titanium curettes or chitosan brushes. Within the limits of the study, the results might indicate the need of more effective submucosal cleaning procedures following peri‐implant surgery.
Variability in virulence of Beauveria spp. soil isolates against Ostrinia nubilalis
Authors: Medo Juraj , Medová Janka , Michalko Jaroslav , Cagáň Ľudovít 
Published: August 2020

AbstractEuropean corn borer (Ostrinia nubilalis) is an important maize pest which is treated mainly by synthetic pesticides with many negative effects for ecosystem and human health. Soil borne entomopathogenic fungi of species belonging to Beauveria genus may provide an alternative strategy for biological control of this pest. In this article, we report results of virulence testing of 46 soil isolates of Beauveria spp. against O. nubilalis in relation to isolates origin and haplotype. All strains were collected from soil using Galleria mellonella bait method. Conidia suspension with concentration 107 conidia in ml was used for virulence test against 4th instar larvae of O. nubilalis at temperature 25°C. After 14 days, mortality of larvae was in the range 34%–96%. Median lethal time LT50 was estimated to 5.5–21.3 days. Mortality was not in relation to habitat or any other environmental parameter of sites where isolates came from. Differences among species were insignificant. Isolates were divided into 8 genetic lineages and 14 haplotypes using sequencing of ITS and Bloc nuclear regions. None of the lineages showed higher mortality than others. Despite more or less virulent isolates being found in each lineage, the three most virulent isolates belonged to the same lineage Beauveria bassiana A3. The four most virulent isolates were compared to commercial isolate GHA to assess medium lethal concentration. LC50 were estimated in range 7.5 × 104 to 9.5 × 105. Three of the four isolates showed equal or greater efficiency than strain GHA.
Persistent inflammation, immunosuppression and catabolism syndrome (PICS) in critically ill children is associated with clinical outcomes: a prospective longitudinal study
Authors: Hauschild D. B. , Oliveira L. D. A. , Ventura J. C. , Farias M. S. , Barbosa E. , Bresolin N. L. , Moreno Y. M. F. 
Published: August 2020

AbstractBackgroundPersistent inflammation, immunosuppression and catabolism syndrome (PICS) has been described in critically ill adults and may contribute to unfavourable outcomes. The present study aimed to describe and characterise PICS in critically ill children (PICS‐ped) and to verify its association with clinical outcomes.MethodsA prospective longitudinal study was conducted in a paediatric intensive care unit (PICU) with children aged between 3 months and 15 years. PICS‐ped, based on adult definition, was described. PICS‐ped was defined as PICU length of stay >14 days; C‐reactive protein > 10.0 mg L−1; lymphocytes <25%; and any reduction of mid‐upper arm circumference Z‐score. Clinical, demographic, nutritional status, nutrition therapy parameters and clinical outcomes were assessed. Statistical analysis comprised Mann–Whitney and Fisher’s chi‐squared tests, as well as logistic and Cox regression. P < 0.05 was considered statistically significant.ResultsIn total, 153 children were included, with a median age of 51.7 months (interquartile range 15.6–123.4 months), and 60.8% male. The mortality rate was 10.5%. The prevalence of PICS‐ped was 4.6%. Days using vasoactive drugs and days using antibiotics were associated with PICS‐ped. PICS‐ped was associated with mortality in crude (odds ratio = 6.67; P = 0.013) and adjusted analysis (odds ratio = 7.14; P = 0.017). PICS‐ped was also associated with PICU and hospital length of stay, as well as duration of mechanical ventilation. Similar results were found in a subset of critically ill children who required mechanical ventilation for more than 48 h.ConclusionsChildren with PICS‐ped required antibiotics or vasoactive drugs for a longer period. PICS‐ped was associated with poor clinical outcomes in critically ill children. More studies are needed to properly define PICS‐ped for this population.
Manifestation and parental assessment of children’s cancer pain at home: An exploratory mixed‐methods study
Authors: Parker Roses , Wiseman Theresa , Twycross Alison , McKeever Stephen 
Published: August 2020

AbstractAims and objectivesTo describe pain manifestation in children with cancer at home and understand how parents assess this pain.BackgroundPain is experienced by children with cancer throughout their cancer journey. Short‐term, and into survivorship, pain has negative physical and psychological consequences. Changes in treatment location mean children with cancer spend more time at home. Little is known about pain experienced by children at home or how parents assess this pain.DesignA mixed‐methods convergent parallel study was reported using STROBE.MethodParents of children with cancer on active treatment were recruited from one tertiary cancer centre. Parental attitudes towards pain expression were assessed using surveys. Parents recorded their child's pain manifestation in pain diaries kept for one month. Interviews captured a deeper understanding of pain manifestation and how parents assess this pain at home. Integration occurred after each data collection method was analysed separately.ResultsPredominantly children were not in pain at home. However, most children experienced at least one episode of problematic pain over the pain diary period. Surveys showed parents held misconceptions regarding children's pain expression. Interviews diverge from surveys and suggest parents used a range of information sources to assess pain.ConclusionChildren with cancer may differ from one another in the manifestation of pain at home resulting in multiple pain trajectories. Parents of children with cancer are able to adequately assess their child's pain using information from multiple sources.Relevance to clinical practice

It is not currently possible to predict which children will experience problematic pain at home, so all parents require pain management education prior to discharge.

Teaching parents to use bundled approaches to pain assessment may accelerate their learning.

Healthcare professionals may benefit from using multiple information sources to assess pain.
Psychosocial oral health‐related quality of life impact: A systematic review
Authors: Su Naichuan , van Wijk Arjen , Visscher Corine M. 
Published: August 2020

AbstractBackgroundPsychosocial wellbeing is an important determinant for patients' oral health‐related quality of life (OHRQoL). Psychosocial impact (PI), together with the dimensions Oral Function, Orofacial Pain and Orofacial Appearance, has been proposed to cover the different areas of OHRQoL.ObjectiveThe objective of the study was to collect further scientific support for the new four‐dimensional structure of OHRQoL. This study is one out of a series of four and focuses on the PI in patients with dental anxiety, oral cancer and periodontitis (PROSPERO registration number: CRD42017064033).MethodsFive databases (Pubmed (Medline), EMBASE, Cochrane, CINAHL and PsycINFO) were electronically searched on 8 June 2017 and updated on 14 January 2019, to identify the studies that measure OHRQoL using the Oral Health Impact Profile (OHIP) for oral health conditions. In this review, studies were included if the mean/median domain scores from OHIP‐14 or OHIP‐49 were available for patients with dental anxiety, oral cancer or periodontitis. The score of the handicap domain from the OHIP was used to assess patients` PI. The handicap domain includes 6 items for OHIP‐49 with a domain score ranging from 0 to 24 and 2 items for OHIP‐14 with a domain score ranging from 0 to 8. For comparison between the 2 versions of the OHIP, the domain score of OHIP‐49 was conversed into a 0 to 8 metric. The domain scores of the included studies were then pooled, separately for each of the included dental disorders.ResultsA total of 2104 records were identified based on the search strategy. After screening of titles and abstracts, 1607 articles were reviewed in full text. Twenty‐three articles met the inclusion criteria for this review and were included in the study. The 23 articles contained 3884 patients, grouped in 30 patient populations and 42 patient samples. The pooled mean scores of PI for dental anxiety, oral cancer and periodontitis were 3.2, 1.9 and 0.8, respectively, on the 0 to 8 metric.ConclusionThis review provides standardised information about the OHRQoL impact for three dental disorders as a model for the PI dimension. Dental anxiety tends to show the strongest effect on the PI dimension, while periodontitis tends to show the weakest effect on the PI dimension. Future studies need to confirm whether the reported differences in PI scores between the three dental disorders are statistically significant.
Effect of membrane integrity on survival competition of Botrytis cinerea upon QoI fungicide pyraclostrobin
Authors: Xiong Hui , Liu Xuefeng , Fan Yuhang , Luan Shaorong , Huang Qingchun 
Published: August 2020

AbstractBotrytis cinerea, the causal agent of the grey mould disease, developed resistance to multiple fungicides. However, the role of cell membrane in survival competition of B. cinerea upon quinone outside inhibitor (QoI) fungicide has not yet been elucidated. In this paper, the enhancement of cystamine, a transglutaminase inhibitor, on membrane integrity of B. cinerea was determined, and the effect of the enhancement on the sensitivity of B. cinerea to pyraclostrobin was investigated. The results showed that pyraclostrobin inhibited mycelial growth with EC50 as 1.122 and 3.042 μg/ml at 24 and 48 hr, respectively. In the treatment of 5 and 50 μg/ml pyraclostrobin, membrane integrity of B. cinerea was broken, causing high permeability, lipid peroxidation, flocculent and malformed surface with vague septum and abundant agglomerates inside and outside the mycelia. Cystamine even at 50 and 200 μg/ml had little inhibitory effect on mycelial growth. However, in presence of 50 or 200 μg/ml cystamine, the mycelia from pyraclostrobin treatment possessed a significantly reduced leakage, lower MDA content, and a revived fibrous and transparent surface. Meanwhile, SEM images showed that membrane integrity of the mycelia was significantly improved and the agglomerates were dramatically disappeared. Synergy assays further revealed that B. cinerea regained less sensitivity to pyraclostrobin inhibition. In conclusion, membrane integrity controls mycelia sensitivity and is required for survival competition of B. cinerea upon pyraclostrobin.
Efficacy of oral torasemide in dogs with degenerative mitral valve disease and new onset congestive heart failure: TheCARPODIEMstudy
Authors: Besche Beatrice , Blondel Thomas , Guillot Emilie , Garelli‐Paar Catherine , Oyama Mark A. 
Published: August 2020

AbstractBackgroundTorasemide is a potent loop diuretic with potential to treat congestive heart failure (CHF) in dogs.ObjectiveEvaluate the efficacy and safety of torasemide compared to furosemide in dogs with first occurrence of CHF caused by degenerative mitral valve disease (DMVD).AnimalsThree hundred and nineteen dogs with new onset CHF attributable to DMVD.MethodsDouble‐blinded randomized noninferiority study of PO torasemide vs furosemide in addition to standard CHF treatment. The primary efficacy criterion was decreased pulmonary edema and cough and no worsening of dyspnea or exercise tolerance at day 14. Secondary endpoints included clinical response at day 84 and time to death, euthanasia, or premature study withdrawal for cardiac reasons.ResultsTorasemide q24h (n = 161) was noninferior to furosemide q12h (n = 158); percentage of dogs meeting primary efficacy criterion at day 14 was similar between groups (torasemide, 74.4% [95% confidence interval (CI), 66.8%‐81.0%] vs. furosemide, 73.5% [95% CI, 65.7%‐80.4%]; risk ratio [RR], 1.01; 95% CI, 0.89‐1.15;P= .87). Efficacy at day 84 showed similar results (RR, 1.05; 95% CI, 0.88‐1.25;P= .6). Dogs receiving torasemide had a longer time to endpoint and were less than half as likely to experience death, euthanasia, or premature study withdrawal (hazard ratio, 0.36; 95% CI, 0.19‐0.65;P= .001) than dogs receiving furosemide at any time during the study.Conclusion and Clinical importanceTorasemide was noninferior to furosemide as first line PO treatment for new onset CHF caused by DMVD. Torasemide significantly decreased risk of cardiac‐related death or premature study withdrawal for cardiac reasons compared to furosemide.
A phosphoinositide 5‐phosphatase from Solanum tuberosum is activated by PAMP‐treatment and may antagonize phosphatidylinositol 4,5‐bisphosphate at Phytophthora infestans infection sites
Authors: Rausche Juliane , Stenzel Irene , Stauder Ron , Fratini Marta , Trujillo Marco , Heilmann Ingo , Rosahl Sabine 
Published: August 2020

Summary

Potato (Solanum tuberosum) plants susceptible to late blight disease caused by the oomycete Phytophthora infestans display enhanced resistance upon infiltration with the pathogen‐associated molecular pattern (PAMP), Pep‐13. Here, we characterize a potato gene similar to Arabidopsis 5‐phosphatases which was identified in transcript arrays performed to identify Pep‐13 regulated genes, and termed StIPP.

Recombinant StIPP protein specifically dephosphorylated the D5‐position of phosphatidylinositol 4,5‐bisphosphate (PtdIns(4,5)P2) in vitro. Other phosphoinositides or soluble inositolpolyphosphates were not converted.

When transiently expressed in tobacco (Nicotiana tabacum) pollen tubes, a StIPP‐YFP fusion localized to the subapical plasma membrane and antagonized PtdIns(4,5)P2‐dependent effects on cell morphology, indicating in vivo functionality. Phytophthora infestans‐infection of N. benthamiana leaf epidermis cells resulted in relocalization of StIPP‐GFP from the plasma membrane to the extra‐haustorial membrane (EHM). Colocalizion with the effector protein RFP‐AvrBlb2 at infection sites is consistent with a role of StIPP in the plant–oomycete interaction. Correlation analysis of fluorescence distributions of StIPP‐GFP and biosensors for PtdIns(4,5)P2 or phosphatidylinositol 4‐phosphate (PtdIns4P) indicate StIPP activity predominantly at the EHM.

In Arabidopsis protoplasts, expression of StIPP resulted in the stabilization of the PAMP receptor, FLAGELLIN‐SENSITIVE 2, indicating that StIPP may act as a PAMP‐induced and localized antagonist of PtdIns(4,5)P2‐dependent processes during plant immunity.
Automated labeling of schematic maps by optimization with knowledge acquired from existing maps
Authors: Lan Tian , Li Zhilin , Peng Qian , Gong Xinyu 
Published: August 2020

AbstractSchematic maps are simplified representations of line networks, aiming to help people quickly and accurately perform route planning and orientation tasks. The automated generation of such maps is generally treated as an optimization problem. Most researchers prefer to optimize network layouts and name labels separately, because optimizing them simultaneously is still intractable. It is found that optimizing network layouts is extensively studied, while optimizing name labels is rarely considered. In the optimization of name labels, constraints can be established with rules from cartographic experts, literature (e.g., specification and technical documents), and/or existing maps. However, some rules from experts and literature cannot be explicitly and mathematically expressed. This study aims to develop an automated labeling method with rules from existing maps. We first acquire the rules (i.e., the potential positions and the preferences of these positions) from some existing schematic maps and then integrate them into an optimization algorithm. Experimental evaluation is conducted by a questionnaire in terms of “ease level of finding name labels,” “congestion level,” and “satisfaction level” using Tianjin and Hong Kong metro schematic maps and the labels of our method. The results show that the proposed method can automatically generate effective labels.
Numerical Modeling of a Photovoltaic/Microchannel Direct-Expansion Evaporator for a CO2 Heat Pump
Authors: Uddin Rony Rajib , Adam Gladen 
Published: August 2020

Abstract
A numerical model of a PV/microchannel direct-expansion evaporator for a CO2 heat pump is developed and validated with experimental data from the literature. The effects of degree of superheating, CO2 mass flux, and evaporation temperature on the amount of heat absorbed, pressure drop in the microchannel evaporator, PV temperature, and electrical efficiency are analyzed. The analysis shows that increasing the degree of superheating decreases the amount of heat absorbed, has minimal effect on the PV temperature (for superheating &lt;15 °C), but reduces the pressure drop. The variation of CO2 mass flux has a minimal effect on the amount of heat absorbed and the PV temperature, but the pressure drop increases with increasing CO2 mass flux. Increasing the evaporation temperature decreases the amount of heat absorbed, reduces the pressure drop, and increases the PV temperature. For average ambient conditions for Fargo, North Dakota, a 5–10 °C of superheating at the evaporator outlet, an evaporator temperature between −5 and +5 °C, and a CO2 mass flux of 330–550 kg · m−2 · s−1 balance maximizing the heat absorption while minimizing the pressure drop. To maximize the PV efficiency, lower evaporation temperatures should be used. At an evaporation temperature of 0 °C and an insolation level of 1000 W · m−2, the CO2 microchannel evaporator causes a 23 °C reduction in PV panel temperature which corresponds to a 1.44% absolute increase in PV efficiency.