bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extraction of pore networks from thin section: A case study from deep marine turbidite outcrop
Authors: Adikusuma R , Prasojo O A , Oktavioni A 
Published: July 2020

Abstract
A reservoir should have pores that can accommodate fluid. This capability is supported by the petrophysical properties which reservoirs have. The petrophysical properties depends on how the sediments were deposited. This study is focused on the deep marine turbidite outcrop. Turbidity currents are a sedimentation process which makes the sediments carried randomly at high velocity and low viscosity. The petrophysical properties such as porosity and permeability could be determined using computational fluid dynamics (CFD) analysis and routine core analysis. The approaches of this study are to analyze the petrophysical properties using CFD analysis and compare the results with the routine core analysis. The samples of this study were nine thin sections collected from the outcrops, especially in the middle and the edges of the turbidite channel. These samples then processed in the CFD software called COMSOL Multiphysics thus the porosity and permeability of these samples could be determined. The results show that the porosity values of the CFD analysis are relatively similar with the routine core analysis has and the permeability values of the CFD analysis are higher than the routine core analysis has.
The Analysis about Synthesis, Structure and Properties of Willemite Ceramic Pigments Obtained by a Sol–Gel Method
Authors: Dimitrov Ts I , Markovska I G , Ibreva Ts H 
Published: July 2020

Abstract
This work focuses on the syntheses of willemite ceramic pigments doped with cobalt and nickel ions (Co2+, Ni2+). The pigments were prepared by the sol−gel process. The phase formation has been studied by X - ray diffraction analysis. The results showed that phase composition depends on sintering temperature, isothermal retention period as well as type of chromophore ion. The basic phase is obtained at even 900 - 1000°C. Color characteristics of the pigments have been measured using the Lovibond Tintometer RT 100 Color–CIELab color measurement. Better results were obtained at pigments synthesized at 1100°C. High temperature ceramic pigments representing solid solution with stable crystalline phase of Zn2SiO4 were obtained. The best pigments have been added to white faience glaze and sanitary ceramics.
Vibration Response Simulation on a High Risk Building with Laminated Rubber Bearing Base Isolation Subjected to Earthquake Excitation
Authors: Hardian F R , Nirbito W 
Published: July 2020

Abstract
In a high risk building like hospitals, laboratories, or school, the response of the building due to earthquake might be very dangerous. To reduce victims and damages in infrastructure, a type of base isolation is installed to the foundation of the building. The base isolation, in form of a laminated rubber bearing, produces a horizontal movement of the structure when subjected to earthquake forces in order to keep the people and equipment safe. Some calculations of the response vibration parameters are observed to determine the optimal characteristics of the base isolation. The Keq Value is 415,120,000 N/m and the total mass of the building is 739,534,249.7 kg as well as the highest vibration force is 4,015,079,348.47 N. The aim of this research is to simulate the lateral motion of the building with base isolation, due to earthquake forces and decide whether the response is as expected of the design.
Storage Allocation For Stocked and Buffer Baskets
Authors: Walitsarangkul Arunrat , Kittithreerapronchai Oran 
Published: July 2020

Abstract
The recent changes in the retailer landscape and the continuous labor shortage in Thailand and have caused many distribution centers to embrace material handling equipment capable of automatically storage and transporting products. This article presents the case study of a home improvement retailer that adopts a vertical lift module (VLM) system into one of its distribution centers. As automatic equipment dedicated for baskets, a VLM system transports two types of baskets, particularly available stock baskets preparing for picking and consolidated baskets waiting for shipping. A preliminary analysis of current operations reveals that the number of baskets allocated for each type is not suitable, resulting in low utilization of the equipment and storage space. After studying the historical data as well as nature of the business, we proposed a simulation to experiment with the effects of the following operating policies (1) the suitable number of baskets allocated for each type (2) storage policy of consolidated baskets and (3) retrieving patterns of consolidated baskets. The results suggest that the suitable level of each factor that reduces the space utilization of 6.67% and vehicles travel time of 37.5%. Nevertheless, travel times of incoming and outgoing lifters are close to similar represented by their utilization.
Simultaneously improved dielectric, optical and conductivity properties of SrLa1−xNdxLiTeO6 double perovskites
Authors: Halizan M Z M , Mohamed Z , Yahya A K 
Published: July 2020

Abstract
In this study, SrLa1-xNdxLiTeO6 (x = 0.00, 0.25, 0.50, 0.75, 1.00) compounds were prepared using the solid-state method, and their structural, optical, dielectric and conductivity properties were investigated. The Rietveld refinement of x-ray diffraction (XRD) data shows that the compound crystallizes in monoclinic symmetry (i.e. P2

1

/n space group). The morphological scanning electron microscopy study reports a larger grain size when the dopant is added. The optical ultraviolet-visible light spectroscopy (UV-Vis) study reveals that the energy band gap decreases as the doping increases from x = 0.00 to 0.50. Dielectric studies using electrochemical impedance spectroscopy (EIS) characterization reveal the non-Debye trend of dielectric real permittivity (ε′) with the enhancement of ε′ at 1 MHz from x = 0.00 to 0.50. ε′ and the dielectric tangent losses (Tan δ) show increment and decrement patterns, respectively, when the temperature is increased. The frequency-dependent conductivity (σ

AC
) plot follows the universal power law at all temperatures, and the σ

AC
behavior in SrLa1-xNdxLiTeO6 is due to the tunneling of polarons.
A variational model for conformation of graphene wrinkles formed on a shrinking solid metal substrate
Authors: Cox Barry , Dyer Tom , Thamwattana Ngamta 
Published: July 2020

Abstract
Chemical vapor deposition is a popular technique for producing high-quality graphene sheets on a substrate. However, the cooling process causes the graphene sheet to experience a strain-induced, out-of-plane buckling. These wrinkles structures can have undesirable effects on the properties of the graphene sheet. We construct a pair of models to analyse the conformation structure of these wrinkles. An arch-shaped wrinkle is first modelled then expanded to incorporate self-adhesion between the wrinkle edges. Variational techniques are employed on both models to determine the optimal conformation for graphene supported on Cu and Ni substrates. We find these models predict a similar structure to experimental analysis of graphene wrinkles on these solid metal substrates.
Adjustment Costs and Factor Demand: New Evidence from Firms’ Real Estate
Authors: Bergeaud Antonin , Ray Simon 
Published: July 2020

Abstract
We study corporate real estate frictions and their effect on firm dynamics and labour demand. We build and simulate a general equilibrium model with heterogeneous firms that predicts the response of firms to a productivity shock in the presence of fixed adjustment costs on real estate. Using a large firm-level database merged with local real estate prices, we then exploit variations in the tax on capital gains to document a causal effect of adjustment costs on firms’ labour demand and derive new results on the causes and implications of firms’ local relocation.
Understanding IV antimicrobial drug losses: the importance of flushing infusion administration sets
Authors: Bolla Balwinder , Buxani Yeshmita , Wong Rebecca , Jones Leslie , Dube Michelle 
Published: July 2020

Abstract

Background
IV drugs are commonly prescribed for inpatient treatment. Where administered as infusions, drug dose loss is incurred if the infusion line is not flushed. Underdosing of IV antimicrobials is of particular concern as reduced treatment efficacy increases the risk of patient deterioration (including sepsis) and development of antimicrobial resistance.

Objectives
To quantify drug loss, raise awareness and provide recommendations to address this patient safety risk effectively.

Methods
Percentage drug loss of 39 IV antimicrobials was calculated for a theoretical patient case scenario, using residual volumes for IV infusion lines utilized within this acute healthcare setting. An adult male patient (70 kg) with good renal function was assumed for drug dosing. Infusion volumes and doses are based on a widely used IV administration guide.

Results
Data revealed the scope and extent of antimicrobial drug losses where infusion lines were not flushed as ranging from 2% to 33%. More than 10% of the drug would be lost for 26 of the 39 antimicrobials assessed, with five of these yielding over 20% loss.

Conclusions
The authors suggest that unintentional antimicrobial underdosing is going unnoticed in clinical practice. Where IV infusion is necessary, flushing of the infusion line to ensure total dose administration is strongly recommended. Risks associated with flushing lines (fluid overloading, bolus dosing, etc.) can be managed with simple measures. The authors call for a national body-led approach to effectively influence healthcare organizations in review of IV administration protocols, ensuring patient safety and care in the NHS.
Role of Chrysomya albiceps (Diptera: Calliphoridae) and Musca domestica (Diptera: Muscidae) Maggot Crop Contents in Identifying Unknown Cadavers
Authors: Mohammad Zainab , Alajmi Reem , Alkuriji Mohammed , Metwally Dina , Kaakeh Walid , Almeaiweed Nasser 
Published: July 2020

AbstractForensic entomology focuses on the analysis of insect larvae present at crime scenes to help identify unknown cadavers. Carrion-feeding maggots store food in a crop located at the anterior end of the gut. DNA recovered from the crop can be amplified, sequenced, and identified to determine the origin of the food. This information could help investigators to identify a missing victim if maggots are discovered at a crime scene in the absence of a corpse. Chrysomya albiceps (Wiedemann) and Musca domestica (Linnaeus) are primary forensic species. Little or no information on the identification of unknown cadavers using C. albiceps and M. domestica larvae is available, and we aimed to compare the effectiveness of using the crop contents of instars of C. albiceps and M. domestica larvae to identify corpses at different time intervals. Two hundred and forty larvae of both species were reared on rat and/or mouse liver, and DNA from crop contents was extracted after different time intervals from different instar larvae. DNA was amplified using specific primers that match the mitochondrial cytochrome oxidase subunit I (mt COI) gene of the food source. Results showed that food provided to larvae affected life span and the ability to be used to identify unknown cadavers. Chrysomya albiceps larvae proved more useful than M. domestica larvae. Moreover, crop contents of third instar larvae of both species fed for 24 h are more useful than contents from other time intervals in identifying unknown tissues. Results are promising and may help investigators to identify unknown/missing victims.
Comparison of visualization tools for single-cell RNAseq data
Authors: Cakir Batuhan , Prete Martin , Huang Ni , van Dongen Stijn , Pir Pinar , Kiselev Vladimir Yu 
Published: July 2020

Abstract
In the last decade, single cell RNAseq (scRNAseq) datasets have grown in size from a single cell to millions of cells. Due to its high dimensionality, it is not always feasible to visualize scRNAseq data and share it in a scientific report or an article publication format. Recently, many interactive analysis and visualization tools have been developed to address this issue and facilitate knowledge transfer in the scientific community. In this study, we review several of the currently available scRNAseq visualization tools and benchmark the subset that allows to visualize the data on the web and share it with others. We consider the memory and time required to prepare datasets for sharing as the number of cells increases, and additionally review the user experience and features available in the web interface. To address the problem of format compatibility we have also developed a user-friendly R package, sceasy, which allows users to convert their own scRNAseq datasets into a specific data format for visualization.
Stakeholder engagement in research on quality of life and palliative care for brain tumors: a qualitative analysis of #BTSM and #HPM tweet chats
Authors: Salmi Liz , Lum Hillary D , Hayden Adam , Reblin Maija , Otis-Green Shirley , Venechuk Grace , Morris Megan A , Griff Megan , Kwan Bethany M 
Published: July 2020

Abstract

Background
Research is needed to inform palliative care models that address the full spectrum of quality of life (QoL) needs for brain tumor patients and care partners. Stakeholder engagement in research can inform research priorities; engagement via social media can complement stakeholder panels. The purpose of this paper is to describe the use of Twitter to complement in-person stakeholder engagement, and report emergent themes from qualitative analysis of tweet chats on QoL needs and palliative care opportunities for brain tumor patients.

Methods
The Brain Cancer Quality of Life Collaborative engaged brain tumor (#BTSM) and palliative medicine (#HPM) stakeholder communities via Twitter using tweet chats. The #BTSM chat focused on defining and communicating about QoL among brain tumor patients. The #HPM chat discussed communication about palliative care for those facing neurological conditions. Qualitative content analysis was used to identify tweet chat themes.

Results
Analysis showed QoL for brain tumor patients and care partners includes psychosocial, physical, and cognitive concerns. Distressing concerns included behavioral changes, grief over loss of identity, changes in relationships, depression, and anxiety. Patients appreciated when providers discussed QoL early in treatment, and emphasized the need for care partner support. Communication about QoL and palliative care rely on relationships to meet evolving patient needs.

Conclusions
In addition to providing neurological and symptom management, specialized palliative care for brain tumor patients may address unmet patient and care partner psychosocial and informational needs. Stakeholder engagement using Twitter proved useful for informing research priorities and understanding stakeholder perspectives on QoL and palliative care.
Development of a Standardized Data Collection Tool for Evaluation and Management of Coronavirus Disease 2019
Authors: Morris Stephen R , Natori Yoichiro , Salguero Douglas , Mantero Alejandro , Ma Ruixuan , de Lima Corvino Daniela F , Fernandez Anmary , Lazo Alex , Vu Christine A , Bjork Lauren , Serota David , Quevedo Jennifer , Vega Ana , Maxam Meshell , DeRonde Kailynn , Barreiro Pablo , Raccamarich Patricia , Alvarez Maria Romero , Skiada Dimitra , Balan Shuba , Ramanathan Maya , Holt Gregory , Gonzales-Zamora Jose , Baracco Gio J , Doblecki-Lewis Susanne , Abbo Lilian M , Lichtenberger Paola N , Alcaide Maria L 
Published: July 2020

Abstract

Background
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ) is responsible for coronavirus disease 2019 (COVID-19), a disease that had not been previously described and for which clinicians need to rapidly adapt their daily practice. The novelty of SARS-CoV-2 produced significant gaps in harmonization of definitions, data collection, and outcome reporting to identify patients who would benefit from potential interventions.

Methods
We describe a multicenter collaboration to develop a comprehensive data collection tool for the evaluation and management of COVID-19 in hospitalized patients. The proposed tool was developed by a multidisciplinary working group of infectious disease physicians, intensivists, and infectious diseases/antimicrobial stewardship pharmacists. The working group regularly reviewed literature to select important patient characteristics, diagnostics, and outcomes for inclusion. The data collection tool consisted of spreadsheets developed to collect data from the electronic medical record and track the clinical course after treatments.

Results
Data collection focused on demographics and exposure epidemiology, prior medical history and medications, signs and symptoms, diagnostic test results, interventions, clinical outcomes, and complications. During the pilot validation phase, there was &lt;10% missing data for most domains and components. Team members noted improved efficiency and decision making by using the tool during interdisciplinary rounds.

Conclusions
We present the development of a COVID-19 data collection tool and propose its use to effectively assemble harmonized data of hospitalized individuals with COVID-19. This tool can be used by clinicians, researchers, and quality improvement healthcare teams. It has the potential to facilitate interdisciplinary rounds, provide comparisons across different hospitalized populations, and adapt to emerging challenges posed by the pandemic.
Non-SUSY Gepner models with vanishing cosmological constant
Authors: Aoyama Koji , Sugawara Yuji 
Published: July 2020

Abstract
In this article we discuss a construction of non-SUSY type II string vacua with the vanishing cosmological constant at the one-loop level based on the generic Gepner models for Calabi–Yau 3-folds. We make an orbifolding of the Gepner models by $\Bbb Z_2 \times \Bbb Z_4$, which asymmetrically acts with some discrete torsions incorporated. We demonstrate that the obtained type II string vacua indeed lead to the vanishing cosmological constant at the one-loop level, whereas any space-time supercharges cannot be constructed as long as we assume chiral forms such as “$ \displaystyle {\cal Q}^{\alpha}_L \equiv \oint dz\, {\cal J}_L^{\alpha}(z) $”. We further discuss possible generalizations of the models described above.
Follistatin Like 5 (FSTL5) inhibits epithelial to mesenchymal transition in hepatocellular carcinoma
Authors: Zhang Deng-Yong , Lei Jia-Sheng , Sun Wan-Liang , Wang Dong-Dong , Lu Zheng 
Published: July 2020

Abstract

Background
Epithelial to mesenchymal transition (EMT) is a key process in determining distant metastasis and intra-hepatic dissemination of hepatocellular carcinoma (HCC). Follistatin (FST) family members are considered to be an attractive therapeutic targets and prognostic indicators in cancers. As a derivative of FST, Follistatin Like 5 (FSTL5) may play a similar role in HCC cells. This study aimed to investigate the expression and function of FSTL5 in HCC and its role in EMT.

Methods

FSTL5, E-cadherin and vimentin in HCC, and paracancerous tissues were detected by immunohistochemistry. Correlation of FSTL5 expression with overall survival was assessed. The proliferation and invasion of HCC cell lines SK-Hep1 and MHCC-LM3 were analyzed by cell counting kit-8 and Transwell assays. The expression of FSTL5, E-cadherin, and vimentin in HCC cells was examined by polymerase chain reaction and Western blot analysis. T-test was used to analyze the difference in proliferation and invasion ability between groups. The Spearman rank correlation test was used to detect the correlation between the expression of FSTL5 and E-cadherin or vimentin.

Results
The expression of FSTL5 in HCC was lower than that in paracancerous tissues (9.97% vs. 82.55%, χ
2 = 340.15, P
< 0.001). Patients with high FSTL5 expression had a better prognosis (χ
2 = 8.22, P = 0.004) and smaller tumor diameter (χ
2 = 45.52, P
< 0.001), less lymph node metastasis (χ
2 = 5.58, P
= 0.02), earlier tumor node metastasis stage (χ
2 = 11.29, P = 0.001), a reduced number of tumors (χ
2 = 5.05, P = 0.02), lower alpha-fetoprotein value (χ
2 = 24.36, P
< 0.001), more probability of hepatitis carrying (χ
2 = 40.9, P
< 0.001), and better liver function grade (χ
2 = 5.21, P = 0.02). Immunohistochemistry showed that FSTL5 expression in HCC tissues was positively correlated with E-cadherin expression (r = 0.38, P < 0.001) and negatively correlated with vimentin expression (r
= −0.385, P
< 0.001). Furthermore, over-expression of FSTL5 up-regulated the expression of E-cadherin and down-regulated the expression of vimentin in SK-Hep1 (negative control [NC] vs. FSTL5-interfering group [Lv-FSTL5]: E-cadherin [t = 45.03, P
< 0.001], vimentin [t = 67, P
< 0.001]) and MHCC-LM3 (NC vs. Lv-FSTL5: E-cadherin [t = 50, P
< 0.001], vimentin [t = 72.75, P
< 0.001]) cells at mRNA level. The same as protein level. In addition, the over-expression of FSTL5 inhibited the proliferation (NC vs. Lv-FSTL5: SK-Hep1, 3 d [t = 7.324, P = 0.018], 4 d [t = 6.23, P = 0.021], 5 d [t = 10.21, P = 0.003]; MHCC-LM3, 3 d [t = 4.32, P = 0.037], 4 d [t = 7.49, P = 0.012], 5 d [t = 9.3661, P = 0.009]) and invasion (NC vs. Lv-FSTL5: SK-Hep1, t = 21.57, P
< 0.001; MHCC-LM3, t = 18.04, P
< 0.001) of HCC cells.

Conclusions
Down-regulation of FSTL5 may contribute to EMT of HCC, and FSTL5 is a potential target in the treatment of HCC.
Case of Bullous Grover Disease
Authors: Li Yumeng M. , Milikowski Clara , Galimberti Fabrizio 
Published: July 2020

Abstract:
Grover disease is an acquired acantholytic dermatosis affecting middle-aged men, with pruritus being the most commonly associated symptom. Grover disease tends to wax and wane and can last between several months to several years. Although Grover disease is usually papular, we report here a patient who presented with mainly vesicular and bullous lesions on his back originally concerning for folliculitis, contact dermatitis, or disseminated herpes simplex viral infection. Skin biopsy demonstrated acantholysis, suprabasal blisters, and a predominantly lymphocytic dermal infiltrate. Tzanck preparation for giant cells, immunohistochemistry for viral markers, and direct immunofluorescence staining were all negative. A diagnosis of bullous Grover disease was made based on clinicopathological correlation. Minocycline was recommended based on report of its efficacy. However, patient declined treatment and his rash self-resolved within a couple of months. This case brings awareness to this atypical variant of Grover disease and encourages physician to include Grover disease in their differential of vesiculobullous disorders.
Diffuse (Generalized) Plane Xanthoma Misdiagnosed as Carotenoderma: Usefulness of Reflectance Confocal Microscopy
Authors: Cota Carlo , Pellacani Giovanni , Lora Viviana , Brancorsini Donatella 
Published: July 2020

Abstract:
Diffuse (generalized) plane xanthoma is a rare normolipemic xanthomatosis, frequently associated with multiple myeloma and monoclonal gammopathy. Its clinical presentation is well described, and in most cases, clinical suspicion is immediate. Rarely, it can clinically present with a diffuse and uniform yellowish discoloration, and in this context, several investigations are required to identify the correct diagnosis. We describe a case characterized by progressive diffuse yellow–orange discoloration lasting about 3 years and classified as carotenoderma in which reflectance confocal microscopy addressed the diagnosis and drove the correct selection of the biopsy site. Definitive diagnosis of diffuse (generalized) plane xanthoma was confirmed later by histological examination.