bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polytobacco product use among current cigarette smokers in Hong Kong, China: results from population surveys (2015-17)
Authors: Chau Siu Long , Wang Man Ping , Wu Yongda , Cheung Yee Tak , Kwong Cho-shing , Lai Vienna , Lam Tai Hing , Ho Sai Yin 
Published: December 2020

Abstract
Background Poly-tobacco product use is increasingly popular, but little is known about the prevalence, trend, and risk factors of such use particularly in non-western countries.Method A representative sample of 1139 current cigarette smokers aged 15+ (84.1% male) were telephone interviewed in Tobacco Control Policy-related Surveys in 2015-2017. Information collected included poly-tobacco use (PTU), smoking and socio-demographic characteristics. Associations of current PTU with related risk factors were analyzed using logistic regression with adjustment for confounders. Prevalence was weighted by age and sex of current cigarette users in the general population.Results 84.1% (95% CI 81.4-86.6%) were exclusive cigarette smokers. 15.9% (13.4-18.6%) were current poly-users, 12.3% (10.2-14.8%) used one tobacco product and 2.52% (1.59-3.97%) used two tobacco products in addition to cigarette. Cigarette use with cigar was more common (6.28%, 4.75-8.27%), and the least used product with cigarette was e-cigarette (1.05%, 0.44-2.50%). The changes in overall prevalence of PTU by number of products use varied in three years. Current PTU was associated with being male (AOR 2.01, 95% CI 1.12-3.61), younger age (AORs range from 1.34-4.65, P for trend < .001) and less ready to quit (2.08, 1.09-3.97). Conclusions Prevalence of PTU increased slowly by year, one tobacco product use with cigarette was more common. The most used tobacco product with cigarette was cigar. Being male, younger and less ready to quit were associated with current PTU.
Structure and trends of international sport nutrition research between 2000-2018: bibliometric mapping of sport nutrition science
Authors: Kiss Anna , Temesi Ágoston , Tompa Orsolya , Lakner Zoltán , Soós Sándor 
Published: December 2020

Abstract
Background: The tool kits of bibliometrics and science mapping provide a standard methodology to map the knowledge base of specific fields of science. The aim of the present research is the analysis of the recent international trends of sport nutrition science, as well as the primary identification of the research topics and results of sport nutrition science via enhanced bibliometric methods for the 2000-2018 time period. Methods: Altogether, 3889 publications were included in this study. We identified the most relevant sport nutrition topics by running a community detection algorithm on the proximity network constructed via network text analysis. The key issues and key concepts of sport nutrition topics as well as their relations were evaluated via network analysis. We also carried a chronological analysis of topics out, and a scientometric evaluative analysis was also created. Results: We identified the four main basic groups from which the 18 most characteristics topics were analyzed. The 18 topics are the following: ‘soccer and physiology’, ‘carbohydrate metabolism’, ‘muscle physiology: alkalosis and acidosis’, ‘muscle mass gain and dietary supplementation’, ‘fluid balance and hydration’, ‘dietary intake and nutrition knowledge’, ‘determination of energy need of athletes’, ‘bone health and female athlete triad’, ‘hydration strategy’, ‘body weight management’, ‘nutritional strategies and human skeletal muscle’, ‘dietary supplementation of nitrates’, ‘oxidative stress and dietary supplement use’, ‘dietary supplement use and doping’, ‘oxidative stress and inflammation and dietary antioxidants’, ‘exercise adaptation and nutritional strategies’, ‘gut microbiota’, ‘celiac disease’. Regarding the size of the topic, researches on sport nutrition science have put the focus on the following three groups: ‘muscle mass gain and dietary supplementation’, ‘carbohydrate metabolism’, ‘oxidative stress and dietary supplement use’. The greatest scientific impact can be ascribed to the following topics: ‘nutritional strategies and human skeletal muscle’, ‘dietary supplementation of nitrates’, ‘body weight management’, and ‘gut microbiota’. Conclusions: Scientific output on sport nutrition has continuously been rising between 2000-2018. The ratio of topics related to sport nutrition but first of all connected to basic research has decreased significantly within all publications. The results of this study confirm the role of science mapping in the identification of specific research topics and primary research directions in the field of sport nutrition science.
Media representations of COVID-19 public health policies: assessing the portrayal of essential health services in Canadian print media
Authors: Ogbogu Ubaka , Hardcastle Lorian 
Published: December 2020

Abstract
Aims: The study assessed how the Canadian print media represented essential healthcare services during the COVID-19 pandemic, including the controversial decision to include liquor and cannabis stores in essential services lists.Methods: Content analysis of sixty-seven articles published in major Canadian English language newspapers between March 23 and April 1, 2020. Articles were analyzed and coded by two raters. Ratings were analyzed in SPSS.Results and Discussion: Few articles in the sample discussed essential healthcare services and the inclusion of liquor and cannabis stores in essential services lists. Majority of the articles that discussed both topics framed the discussion positively and consistently with current knowledge and evidence.Conclusion: Canadian print media representations of essential healthcare services and associated public debate are largely descriptive and, therefore, fail to engage critically with or advance public understanding of an important health policy issue.
Prevalence of Depression among HIV-Positive Adults on Antiretroviral Therapy in O.R. Tambo, Eastern Cape, South Africa: A cross-sectional descriptive study
Authors: Zimasa Dlulane Yola , Teke Apalata , Abaver Dominic Targema 
Published: December 2020

Abstract
Background Living with HIV/AIDS is associated with negative emotional and bodily symptoms; however, there is paucity of data on the prevalence and associated factors depression among this population. This study investigate the prevalence and factors contributing to depression among HIV-positive adults on antiretroviral therapy (ART) in O.R. Tambo Eastern Cape, South Africa. Method This cross-sectional descriptive study involved 334 adults receiving ART in the two Community Health Centers in OR Tambo District, Eastern Cape, South Africa. The Beck’s Depression Inventory (BDI-II) was used to collect data, in addition to a semi-structured questionnaire on coping mechanism and challenges in seeking help with depressive symptoms. Multiple logistic regression analysis were used to assess the factors associated with depression among the HIV-positive adults. Results The prevalence of depression among the HIV-positive adults receiving ART was 44%, and the majority of the patient’s depression fall within the borderline and moderate threshold. The prevalence of depression was significantly higher among females (71.0%; p < 0.0003) and unemployed (73.0%; p < 0.0014) HIV-positive adults. Participants not benefiting from any form of social grant exhibited higher prevalence of depression (79%). Race (p=0.590), age (p=0.338) and married participants (p=0.511) show no statistical significant association between HIV-positive adults accessing ART and depression. Unadjusted logistic regression model show being female (OR = 1.99, 95% CI: 1.23-3.23; p < 0.003) and unemployed (OR =1.73, 95% CI: 1.08-2.77; p < 0.014) were significantly associated with a likelihood of depression. Majority of the participants who could express their feelings of HIV disease and challenges in accessing ART felt more depressed (85%) compared to those who could not express their feelings.Conclusion The rate of depression among HIV/AIDS patients receiving ART is high. Early detection of depression and the challenges associated with accessing treatment and treating would help in improving the compliance to treatment as well as quality of life.
Changes in Healthcare Spending Attributable to Obesity: Payer- and Service-Specific Estimates
Authors: Broek-Altenburg Eline van den , Atherly Adam , Holladay Evon 
Published: December 2020

Abstract
Background: National efforts to control US healthcare spending are potentially undermined by changes in patient characteristics, and in particular increases in rates of obesity. The objective of this study was to provide current estimates of the effect of obesity on healthcare spending overall, by service line and by payer using the NIH classifications for BMI. Methods: We used a quasi-experimental design and analyzed the data using generalized linear models and two-part models to estimate obesity-attributable spending. Data was drawn from the 2006 and 2016 Medical Expenditures Panel Survey. We identified individuals in the different BMI classes based on self-reported height and weight. Results: Total medical costs attributable to obesity rose to $126 billion per year by 2016, although the marginal cost of obesity declined for all obesity classes. The overall spending increase was due to an increase in obesity prevalence and a population shift to higher obesity classes. Obesity related spending between 2006 and 2016 was relatively constant due to decreases in inpatient spending, which were only partially offset by increases in outpatient spending. Conclusions: Obesity related spending between 2006 and 2016 was relatively constant due to decreases in inpatient spending, which were only partially offset by increases in outpatient spending. Obesity class 2 and 3 were the main factor driving spending increases, suggesting that persons over BMI of 35 should be the focus for controlling spending.
Quality of life of patients living with psoriasis: a qualitative study
Authors: Meneguin silmara , Godoy Natalia , Pollo Camila Fernandes , Miot Helio Amante , Oliveira Cesar 
Published: December 2020

Abstract
Background: Psoriasis is a multifactorial inflammatory disease prevalent in dermatology. We aimed to understand the perceptions of patients living with psoriasis in relation to their quality of life and to identify aspects to improve it. Methods: This is qualitative research carried out in a dermatology outpatient clinic of the São Paulo State University (UNESP) medical school, Botucatu, Brazil, with 81 psoriasis patients. The interviews were transcribed and analysed using the Discourse of the Collective Subject method (DCS). Results: Quality of life was linked to well-being, happiness, leisure, good food and financial stability. However, disease symptoms, social and clothing restrictions, impairment of professional activities and the absence of a cure, negatively influenced their perceptions. Suggestions for improvements included an increase of public awareness, stress reduction, disease acceptance and multidisciplinary care. Conclusion: The meanings of quality of life revealed by the participants are subjective, multidimensional, linked to moments experienced by them and to the health-disease process. Public health policies promoting reduction in social stigma and stress as well as multidisciplinary approaches towards care can contribute to improvements of QoL in psoriasis.
Clinical validation of kinematic assessments of post-stroke upper limb movements with a multi-joint arm exoskeleton
Authors: Grimm Florian , Kraugmann Jelena , Naros Georgios , Gharabaghi Alireza 
Published: December 2020

Abstract
BACKGROUND: The clinical evaluation of the upper limb of severely impaired stroke patient is challenging. Sensor-based assessments may allow for an objective evaluation of this patient population. This study investigated the validity of a device-assisted approach in comparison to the clinical outcome that it is supposed to reflect. METHODS: In nineteen severely impaired chronic stroke patients, we applied a gravity-compensating, multi-joint arm exoskeleton (Armeo Spring) and compared this sensor-based assessment with the clinical outcome measure Upper Extremity Fugl-Meyer Assessment (UE-FMA) scale. Specifically, we assessed separately and subsequently the range of motion in joint space for four single joints (i.e., angles of wrist, elbow, arm, and shoulder movement), and the closing and opening of the hand with a pressure sensor placed in the handle. The same position (neutral zero) with a distance of 90 degrees between forearm and upper arm was taken as the starting position for all assessments. RESULTS: Within the kinematic parameters, a strong correlation was observed between wrist and elbow movements (r > 0.7, p<0.003; Bonferroni corrected). The UE-FMA was significantly predicted by a multiple regression model (F (5, 13) = 12.22, p < 0.0005, adj. R2 = 0.83). Both shoulder rotation and grip pressure added significantly (p < 0.05) to the prediction with the standardized coefficients β of 0.55 and 0.38, respectively. CONCLUSIONS: By applying an exoskeleton-based self-contained evaluation of single-joint movements, a clinically valid assessment of the upper limb range of motion in severely impaired stroke patients is feasible. Shoulder rotation contributed most relevantly to the prediction of the clinical status. These findings need to be confirmed in a large, independent patient cohort.
The use of 3D printing pelvis and hip in a complex THA: clinical experience and reports of literature
Authors: Huang Chenyu , Yao Qingqiang , Liu Wei , Xu Yan , Tang Cheng , Wei Bo , Li Jiayi , Wang Liming 
Published: December 2020

Abstract
Background: Total hip arthroplasty(THA) is a good solution of developmental dysplasia of the hip(DDH). However, patients diagnosed with Crowe type IV are difficult to deal with. With traditional operation skills, the operation time is quite long and the patients will lose a lot of blood.Case presentation: We present the case of a 58-year-old male patient who underwent left THA due to Crowe type IV DDH with the help of 3D printing models. Before the operation, we put the CT image into a computer software named mimics. After getting the stl. document, we use 3D printer to print the models out. By using the models, we planned the operation in advance. And after sterilizing the models, we put them in the operation area, which saves a lot of operation time and reduces much blood loss by giving surgeons a better anatomy view. Conclusion: THA with the help of 3D printing pelvis and femur can result in a relatively short recovery time and provide good clinical efficacy of type IV DDH patients.
Genetic diversity analysis of brown marmorated stink bug, Halyomorpha halys based on mitochondrial COI and COII haplotypes
Authors: Yan Juncong , Pal Chandan , Anderson Diane , Vétek Gábor , Farkas Péter , Burne Allan , Fan Qing-Hai , Zhang Jinping , Gunawardana Disna N. , Balan Rebijith Kayattukandy , George Sherly , Li Dongmei 
Published: December 2020

Abstract
Background: In the past decade, the brown marmorated stink bug (BMSB), Halyomorpha halys (Hemiptera: Pentatomidae) has caused extensive damage to global agriculture. As a high-risk pest for many countries, including New Zealand, it is important to explore its genetic diversity to enhance our knowledge on and devise management strategies for BMSB populations. In this study, two mitochondrial genes, Cytochrome c oxidase I (COI) and Cytochrome c oxidase II (COII) were used to explore the genetic diversity among 463 BMSB individuals collected from 12 countries. Result: In total, 51 COI and 29 COII haplotypes of BMSB were found, which formed 59 combined haplotypes (5 reported and 54 novel). Of these, H1h1 was the predominant haplotype. The haplotype diversity (Hd) and nucleotide diversity (π) were high while the neutrality (Fu's Fs) values were negative for the BMSB populations in the native countries, China, and Japan. For the BMSB populations from the invaded countries, the Fu's Fs values were negative for populations from Chile, Georgia, Hungary, Italy, Romania, Turkey, and USA, indicating that those populations are under demographic expansion. In comparison, the Fu's Fs values were positive for the populations from Austria, Serbia, and Slovenia, revealing a potential population bottleneck. Analysis of molecular variance (AMOVA) suggested that significant genetic difference exist between groups of populations: China, Japan, and the invasive populations. Conclusion: This study revealed that the haplotype diversity of the BMSB populations was high in those two studied countries where BMSB is native to (China and Japan) but low in those countries which have been invaded by the species. The analysis indicated that multiple invasions of BMSB occurred and a new stable genetic cluster has established in Europe and the USA. The study also revealed that three ancestral lines and most of the novel haplotypes were evolved from them. Moreover, we observed two genetic clusters in the invasive populations that are formed during different invasion events. Our study provided a comprehensive overview on the global haplotypes distribution thus expanding the existing knowledge on BMSB genetic diversity that potentially could play an important role in formulating feasible pest management strategies, especially biocontrol.
Severe Vision Impairment and Blindness in Hospitalized Patients: A Nationwide Study
Authors: Harris Che , Wright Scott M 
Published: December 2020

Abstract
Background: Outcomes among hospitalized patients with severe vision impairment or blindness have not been extensively explored. This study sought to determine clinical and resource utilization outcomes in patients with severe vision impairment/blindness (SVI/B). Because the obesity epidemic is also on the rise and underrecognized in hospital settings, we also sought to understand its impact among patients with SVI/B.Methods: We conducted a retrospective study using the National Inpatient Sample for the year 2017; hospitalized adults with and without SVI/B were compared. In addition, for all patients with SVI/B, we compared those with and without obesity. Multiple logistic regression and linear analysis were used to evaluate mortality, disposition, length of stay, and hospital charges. We adjusted for age, sex, race, comorbidities, insurance, and income.Results: 30,420,907 adults were hospitalized, of whom 37,200 had SVI/B. Patients with SVI/B were older (mean age ± SEM: 66.4±0.24 vs. 57.9±0.09 years, p <0.01), less likely to be female (50% vs 57.7%, p <0.01), more frequently insured by Medicare (75.7% vs 49.2%, p <0.01), and had more comorbidities (Charlson comorbidity score ≥ 3: 53.2% vs 27.8%, p <0.01). Patients with SVI/B had a higher in-hospital mortality rate (3.9% vs 2.2%; p<0.01), and they were less likely discharged home (adjusted Odds Ratio {aOR} =0.54, [Confidence Interval (CI) 0.51-0.58]; p <0.01) compared to those without visual impairment. Hospital charges were not significantly different (adjusted Mean Difference {aMD} = $247 CI [-$2,474-2,929]; p=0.85) but length of stay was longer (aMD= 0.5 days CI [0.3-0.7]; p<0.01) for those with SVI/B. Visually impaired patients who were also obese had higher total hospital charges compared to those without obesity (mean difference: $9,821 [CI $1,375-$18,268]; p =0.02).Conclusion: Patients admitted to American hospitals in 2017 who had severe vision impairment or blindness had worse clinical outcomes and greater resources utilization. Hospital-based healthcare professionals should recognize that because those with visual impairment are at risk for worse outcomes, extra attention to detail may be warranted to minimize the propagation of such disparity.
Electric modulation of conduction in MAPbBr3 single crystals
Authors: Ke Shanming , Luo Shangyu , Gong Jinhui , Qiu Liwen , Liang Renhong , Zhou Yangbo , Luo Bingcheng , Cheng Baochang , Wang Li , shu longlong 
Published: December 2020

Abstract
The resistive switching (RS) mechanism of hybrid organic-inorganic perovskites is an open question until now. Here, a switchable diode-like RS behavior in MAPbBr3 single crystals using Au (or Pt) symmetric electrodes is reported. Both the high resistance state (HRS) and low resistance state (LRS) are electrode-area dependent and light responsive. We propose an electric-field-driven inner p-n junction accompanied by a trap-controlled SCLC conduction mechanism to explain this switchable diode-like RS behavior in MAPbBr3 single crystals.
Efficacy of two-week quadruple bismuth treatment versus levofloxacin concomitant Helicobacter Pylori infection regimen as empirical first-line therapy Syrian patients. A randomized controlled trial.
Authors: Alhalabi Marouf Muhammad , Alassi Mohammed Waleed , Eddin Kamal Alaa , Cheha Khaled 
Published: December 2020

Abstract
Introduction: Antibiotic-resistant reduces the efficacy of conventional triple therapy for Helicobacter Pylori infections worldwide, lead to varying treatment protocols according to locations.Aim: Primary outcome was eradication rates of bismuth quadruple (BQ) and levofloxacin concomitant (LC) as empirical first-line treatment by intention to treat (ITT) in a referral hospital in Syria.Design: an open‑label parallel blind randomized controlled trial.Materials and Methods: We randomly assigned seventy-eight naïve who tested positive for Helicobacter Pylori gastric infection, with a 1:1 ratio to receive either BQ (bismuth subsalicylate 524 mg four times daily, doxycycline 100 mg, tinidazole 500 mg, and esomeprazole 20 mg, each twice daily for two weeks), or LC (levofloxacin 500 mg daily, tinidazole 500 mg, amoxicillin 1000 mg, and esomeprazole 20 mg each twice daily for two weeks). We confirmed Helicobacter Pylori eradication by stool antigen test by eight weeks.Results: Thirty-nine patients were allocated in each group. In the BQ group, thirty-eight patients completed the follow-up, thirty patients were cured. While in the LC group, thirty-nine completed the follow-up, thirty-two patients were cured. The ITT eradication rates of the BQ and LC groups were 76.92%, and 82.05%, respectively. Odds ratio with 95% confidence interval according to ITT was 1.371 [0.454-4.146]. We didn’t report serious adverse effects.Conclusions:Both therapy regimens had acceptable rates of eradication. we suggest using both regimens as empirical first-line therapy in the treatment of Helicobacter Pylori infection in the Syrian population.Clinicaltrial.gov, NCT04348786
Measurement of Neutrino's Magnetic Monopole Charge, Aether, Dark Energy and Cause of Quantum Mechanical Uncertainty
Authors: Jeong Eue Jin , Edmondson Dennis 
Published: December 2020

Abstract
Charge conservation in the theory of elementary particle physics is one of the best-established principles in physics. As such, if there are magnetic monopoles in the universe, the magnetic charge will most likely be a conserved quantity like electric charges. If neutrinos are magnetic monopoles, as physicists have speculated the possibility, then neutrons must also have a magnetic monopole charge, and the Earth should show signs of having a magnetic monopole charge on a macroscopic scale. To test this hypothesis, experiments were performed to detect the magnetic monopole's effect near the equator by measuring the Earth's radial magnetic force using two balanced high strength neodymium rods magnets that successfully identified the magnetic monopole charge. From this observation, we conclude that at least the electron neutrino which is a byproduct of weak decay of the neutron must be magnetic monopole. We present mathematical expressions for the vacuum electric field based on the findings and discuss various physical consequences related to the symmetry in Maxwell's equations, the origin of quantum mechanical uncertainty, the medium for electromagnetic wave propagation in space, and the logistic distribution of the massive number of magnetic monopoles in the universe. We elaborate on how these seemingly unrelated mysteries in physics are intimately intertwined together around magnetic monopoles.