bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impacts of climate change on hurricane flood hazards in Jamaica Bay, New York
Authors: Marsooli Reza , Lin Ning 
Published: November 2020

AbstractSea level rise (SLR) and tropical cyclone (TC) climatology change could impact future flood hazards in Jamaica Bay—an urbanized back-barrier bay in New York—yet their compound impacts are not well understood. This study estimates the compound effects of SLR and TC climatology change on flood hazards in Jamaica Bay from a historical period in the late twentieth century (1980–2000) to future periods in the mid- and late-twenty-first century (2030–2050 and 2080–2100, under RCP8.5 greenhouse gas concentration scenario). Flood return periods are estimated based on probabilistic projections of SLR and peak storm tides simulated by a hydrodynamic model for large numbers of synthetic TCs. We find a substantial increase in the future flood hazards, e.g., the historical 100-year flood level would become a 9- and 1-year flood level in the mid- and late-twenty-first century and the 500-year flood level would become a 143- and 4-year flood level. These increases are mainly induced by SLR. However, TC climatology change would considerably contribute to the future increase in low-probability, high-consequence flood levels (with a return period greater than 100 year), likely due to an increase in the probability of occurrence of slow-moving but intense TCs by the end of twenty-first century. We further conduct high-resolution coastal flood simulations for a series of SLR and TC scenarios. Due to the SLR projected with a 5% exceedance probability, 125- and 1300-year flood events in the late-twentieth century would become 74- and 515-year flood events, respectively, in the late-twenty-first century, and the spatial extent of flooding over coastal floodplains of Jamaica Bay would increase by nearly 10 and 4 times, respectively. In addition, SLR leads to larger surface waves induced by TCs in the bay, suggesting a potential increase in hazards associated with wave runup, erosion, and damage to coastal infrastructure.
Trace elements fingerprint of feathers differs between breeding and non-breeding areas in an Afro-Palearctic migratory bird, the barn swallow (Hirundo rustica)
Authors: Parolini Marco , Sturini Michela , Maraschi Federica , Profumo Antonella , Costanzo Alessandra , Caprioli Manuela , Rubolini Diego , Ambrosini Roberto , Canova Luca 
Published: November 2020

AbstractTrace elements are widespread contaminants that can potentially threaten ecosystems and human health. Considering their distribution and toxicity, monitoring their presence in animals represents a priority in environmental risk assessment. Migratory birds have been suggested to be useful biomonitors for trace elements because they can provide information on contaminants even from remote areas that they may exploit during their life cycle. The aim of this study was to analyse the contamination fingerprint of trace elements of African non-breeding staging grounds and European breeding areas in a long-distance migratory passerine bird, the barn swallow (Hirundo rustica). We collected feathers grown in the African non-breeding grounds and those grown in the breeding areas of Northern Italy and measured the levels of 12 trace elements (Al, As, Cd, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se and Zn) by DRC-ICP-MS. Multivariate analysis showed that elemental profiles of feathers grown in African non-breeding areas and in the Italian breeding ones clearly differed, with feathers grown in Africa showing higher concentrations of Al, Cu, Fe, Mn and Ni, but lower concentrations of As, Se and Zn, compared to those grown in Italy. In addition, levels of trace elements were age-dependent, with higher levels in older individuals than in younger ones. Our results add to the growing evidence that feathers of long-distance migratory birds are useful tools to monitor trace elements contamination profiles across continents.
Piecing together a new mosaic: Gravettian lithic resources and economic territories in the Western Pyrenees
Authors: Calvo Aitor , Arrizabalaga Alvaro 
Published: November 2020

AbstractTo palliate the current scarcity of information about lithic raw materials in the Western Pyrenees during the Gravettian, the study of ten assemblages has explored the flint procurement patterns and economic organisation of the territory. The study was based on the macro- and microscopic analysis of the different lithic remains. A wide range of flint varieties were used, including some excellent rocks for knapping and others of poorer quality. This diversified catchment pattern was defined by the criteria of quality and suitability for reduction. Although procurement took place mostly at the primary outcrops, there is some evidence of limited acquisition in secondary deposits. Within the economic territory of the Western Pyrenees, divergences in the connections between the outcrops on one side of the mountains and the archaeological sites on the other may indicate different territorial or economic roles for each side. In general terms, the northern side may have been more residential with more stable habitation, while the southern side was linked with logistic tasks and more seasonal occupation. The economic connections between this territory and surrounding areas revealed by the lithic resources are the reflection of inter-group contacts and an economic mosaic imbricated with a cultural or symbolic one.
Impact of deliberate practice on evidence-based medicine attitudes and behaviours of health care professionals
Authors: Draaisma Eelco , Maggio Lauren A. , Bekhof Jolita , Jaarsma A. Debbie C. , Brand Paul L. P. 
Published: November 2020

Introduction Although evidence-based medicine (EBM) teaching activities may improve short-term EBM knowledge and skills, they have little long-term impact on learners’ EBM attitudes and behaviour. This study examined the effects of learning EBM through stand-alone workshops or various forms of deliberate EBM practice.
Methods We assessed EBM attitudes and behaviour with the evidence based practice inventory questionnaire, in paediatric health care professionals who had only participated in a stand-alone EBM workshop (controls), participants with a completed PhD in clinical research (PhDs), those who had completed part of their paediatric residency at a department (Isala Hospital) which systematically implemented EBM in its clinical and teaching activities (former Isala residents), and a reference group of paediatric professionals currently employed at Isala’s paediatric department (current Isala participants).
Results Compared to controls (n = 16), current Isala participants (n = 13) reported more positive EBM attitudes (p < 0.01), gave more priority to using EBM in decision making (p = 0.001) and reported more EBM behaviour (p = 0.007). PhDs (n = 20) gave more priority to using EBM in medical decision making (p < 0.001) and reported more EBM behaviour than controls (p = 0.016).
Discussion Health care professionals exposed to deliberate practice of EBM, either in the daily routines of their department or by completing a PhD in clinical research, view EBM as more useful and are more likely to use it in decision making than their peers who only followed a standard EBM workshop.
Kooperation zwischen Kinder- und Jugendpsychiatrie und Kinder- und Jugendhilfe mit speziellem Schwerpunkt auf die Unterbringung von Kindern und Jugendlichen in sozialpädagogischen Wohnformen
Authors: Noske Judith , Thun-Hohenstein Leonhard 
Published: November 2020

ZusammenfassungKinder- und Jugendpsychiatrie und Kinder- und Jugendhilfe betreuen viele gemeinsame Kinder und Jugendliche. Insbesondere bei den schwierigsten Kindern und Jugendlichen ist eine Kooperation am meisten gefordert. Viele dieser schwierigen Kinder und Jugendlichen kommen aus schwierigen Lebensverhältnissen, sind häufig traumatisiert und zeigen stark externalisierendes Verhalten. Die Unterbringung in einer extrafamilialen Wohnform stellt die Beteiligten aller Systeme häufig vor große Probleme.Die Kinder- und Jugendpsychiatrie kann auf allen Ebenen wertvolle Beiträge leisten. Einerseits im Rahmen der spezifischen Kinder- und Jugendpsychiatrischen Diagnostik und Behandlung, ganz besonders im Konsiliar- und Liäsondienst und/oder in kooperativen Einrichtungen oder Betreuungsformaten. Dieses Angebot wird anhand der von der Kinder- und Jugendhilfe angebotenen Wohnformen diskutiert und konkrete Vorschläge zur Umsetzung diese Kooperation dargestellt.
Enhancing network modularity to mitigate catastrophic forgetting
Authors: Chen Lu , Murata Masayuki 
Published: November 2020

AbstractCatastrophic forgetting occurs when learning algorithms change connections used to encode previously acquired skills to learn a new skill. Recently, a modular approach for neural networks was deemed necessary as learning problems grow in scale and complexity since it intuitively should reduce learning interference by separating functionality into physically distinct network modules. However, an algorithmic approach is difficult in practice since it involves expert design and trial and error. Kashtan et al. finds that evolution under an environment that changes in a modular fashion leads to the spontaneous evolution of a modular network structure. In this paper, we aim to solve the reverse problem of modularly varying goal (MVG) to obtain a highly modular structure that can mitigate catastrophic forgetting so that it can also apply to realistic data. First, we confirm that a configuration with a highly modular structure exists by applying an MVG against a realistic dataset and confirm that this neural network can mitigate catastrophic forgetting. Next, we solve the reverse problem, that is, we propose a method that can obtain a highly modular structure able to mitigate catastrophic forgetting. Since the MVG-obtained neural network can relatively maintain the intra-module elements while leaving the inter-module elements relatively variable, we propose a method to restrict the inter-module weight elements so that they can be relatively variable against the intra-module ones. From the results, the obtained neural network has a highly modular structure and can learn an unlearned goal faster than without this method.
Epidemic spreading and control strategies in spatial modular network
Authors: Gross Bnaya , Havlin Shlomo 
Published: November 2020

AbstractEpidemic spread on networks is one of the most studied dynamics in network science and has important implications in real epidemic scenarios. Nonetheless, the dynamics of real epidemics and how it is affected by the underline structure of the infection channels are still not fully understood. Here we apply the susceptible-infected-recovered model and study analytically and numerically the epidemic spread on a recently developed spatial modular model imitating the structure of cities in a country. The model assumes that inside a city the infection channels connect many different locations, while the infection channels between cities are less and usually directly connect only a few nearest neighbor cities in a two-dimensional plane. We find that the model experience two epidemic transitions. The first lower threshold represents a local epidemic spread within a city but not to the entire country and the second higher threshold represents a global epidemic in the entire country. Based on our analytical solution we proposed several control strategies and how to optimize them. We also show that while control strategies can successfully control the disease, early actions are essentials to prevent the disease global spread.
Neutron star mergers and how to study them
Authors: Burns Eric 
Published: November 2020

AbstractNeutron star mergers are the canonical multimessenger events: they have been observed through photons for half a century, gravitational waves since 2017, and are likely to be sources of neutrinos and cosmic rays. Studies of these events enable unique insights into astrophysics, particles in the ultrarelativistic regime, the heavy element enrichment history through cosmic time, cosmology, dense matter, and fundamental physics. Uncovering this science requires vast observational resources, unparalleled coordination, and advancements in theory and simulation, which are constrained by our current understanding of nuclear, atomic, and astroparticle physics. This review begins with a summary of our current knowledge of these events, the expected observational signatures, and estimated detection rates for the next decade. I then present the key observations necessary to advance our understanding of these sources, followed by the broad science this enables. I close with a discussion on the necessary future capabilities to fully utilize these enigmatic sources to understand our universe.
Fertility, immigration, and lifetime wages under imperfect labor substitution
Authors: Guest Ross , Parr Nick 
Published: November 2020

AbstractThis paper provides new insights into the effect of birth cohort size on cohort lifetime wages and its sensitivity to the future trajectories of immigration and fertility. The main innovation is to relax the typical assumption of perfect substitution of labor by age. The effect of imperfect substitution of labor by age is to qualify the standard result that smaller birth cohorts are likely to enjoy relatively high wages since that result depends on the size of co-worker cohorts. The positive small cohort effect on lifetime wages therefore depends on demographic patterns, which are simulated here through low and high fertility and immigration projections. The analysis applies to actual and projected cohorts for Australia and tests the sensitivity to alternative demographic parameters, and the substitution and discount parameters. The effects of imperfect substitution can amount several percentage points of lifetime wages.
Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship
Authors: Coffin Susan E. , Abanyie Francisca , Bryant Kristina , Cantey Joseph , Fiore Anthony , Fritz Stephanie , Guzman-Cottrill Judith , Hersh Adam L. , Huskins W. Charles , Kociolek Larry K. , Kronman Matthew , Lautenbach Ebbing , Lee Grace , Linam Matthew , Logan Latania K. , Milstone Aaron , Newland Jason , Nyquist A. Christine , Palazzi Debra L. , Patel Sameer , Puopolo Karen , Reddy Sujan C. , Saiman Lisa , Sandora Thomas , Shane Andi L. , Smith Michael , Tamma Pranita D. , Zaoutis Theoklis , Zerr Danielle , Gerber Jeffrey S. ,   for the CDC Prevention Epicenters Program
Published: November 2020

AbstractObjective:To develop a pediatric research agenda focused on pediatric healthcare-associated infections and antimicrobial stewardship topics that will yield the highest impact on child health.Participants:The study included 26 geographically diverse adult and pediatric infectious diseases clinicians with expertise in healthcare-associated infection prevention and/or antimicrobial stewardship (topic identification and ranking of priorities), as well as members of the Division of Healthcare Quality and Promotion at the Centers for Disease Control and Prevention (topic identification).Methods:Using a modified Delphi approach, expert recommendations were generated through an iterative process for identifying pediatric research priorities in healthcare associated infection prevention and antimicrobial stewardship. The multistep, 7-month process included a literature review, interactive teleconferences, web-based surveys, and 2 in-person meetings.Results:A final list of 12 high-priority research topics were generated in the 2 domains. High-priority healthcare-associated infection topics included judicious testing for Clostridioides difficile infection, chlorhexidine (CHG) bathing, measuring and preventing hospital-onset bloodstream infection rates, surgical site infection prevention, surveillance and prevention of multidrug resistant gram-negative rod infections. Antimicrobial stewardship topics included β-lactam allergy de-labeling, judicious use of perioperative antibiotics, intravenous to oral conversion of antimicrobial therapy, developing a patient-level “harm index” for antibiotic exposure, and benchmarking and or peer comparison of antibiotic use for common inpatient conditions.Conclusions:We identified 6 healthcare-associated infection topics and 6 antimicrobial stewardship topics as potentially high-impact targets for pediatric research.
Dirivultidae (Copepoda: Siphonostomatoida) from hydrothermal vent fields in the Okinawa Trough, North Pacific Ocean, with description of one new species
Authors: Uyeno Daisuke , Kakui Keiichi , Watanabe Hiromi K. , Fujiwara Yoshihiro 
Published: November 2020

AbstractTwo species of dirivultid copepod (Siphonostomatoida),Stygiopontius senckenbergiIvanenko & Ferrari, 2013 andDirivultus kaikosp. nov., were discovered from hydrothermal vent fields in the Okinawa Trough, the western North Pacific. SinceS. senckenbergiwas originally described based on two adult males from the New Ireland Fore-Arc system, Papua New Guinea, the discovery here represents the second record. This species was attached on ventral setae covered with filamentous bacteria of the deep-sea squat lobsterShinkaia crosnieri(Decapoda: Munidopsidae). The female ofS. senckenbergiis described for the first time as well as the nauplius I and the copepodid IV. Sexual dimorphism is shown on several appendages (i.e. antennule, leg 2 and leg 5). The nauplius I shows typical lethithotrophic characteristics.Dirivultus kaikosp. nov., which was found on the tentacular crown of the siboglinid tubewormLamellibrachia columna, differs from its two congeners by the antennule, maxilliped and leg 5 of both sexes. These are the second and third dirivultid species to be reported from Japan.
Triaging and adaptations of surveillance of cancer services in the COVID pandemic
Authors: Lewis Shirley , Gurram Lavanya , Velu Umesh , Sharan Krishna 
Published: November 2020

AbstractIntroduction:Coronavirus disease (COVID-19) has significantly challenged the access to cancer care and follow-up for a patient with cancer.Methods:Based on published literature and our experiences, it is reasonable to presume that clinical examination and follow-up visits have been significantly curtailed worldwide in order to adhere to the new norms during the pandemic. Although telephonic and telemedicine consultations may help bridge a few gaps, completely dispensing with in-person consultation has its challenges, especially in low middle-income countries. Telephonic consultations could facilitate triaging of ambulatory cancer patients and allocation of face-to-face consultations for high priority patients.Conclusions:We propose a telephonic consultation-based triaging approach for ambulatory cancer patients in order to identify those needing in-hospital consultations.
Placebo response mitigation with a participant-focused psychoeducational procedure: a randomized, single-blind, all placebo study in major depressive and psychotic disorders
Authors: Cohen Elan A. , Hassman Howard H. , Ereshefsky Larry , Walling David P. , Grindell Vera M. , Keefe Richard S. E. , Wyka Katarzyna , Horan William P. 
Published: November 2020

AbstractThe remarkably high and growing placebo response rates in clinical trials for CNS indications, such as depression and schizophrenia, constitute a major challenge for the drug development enterprise. Despite extensive literature on participant expectancies and other potent psychosocial factors that perpetuate placebo response, no empirically validated participant-focused strategies to mitigate this phenomenon have been available. This study evaluated the efficacy of the Placebo-Control Reminder Script (PCRS), a brief interactive procedure that educates participants about factors known to cause placebo response, which was administered prior to the primary outcome assessments to subjects with major depressive or psychotic disorders who had at least moderate depression. Participants were informed they would participate in a 2-week randomized clinical trial with a 50% chance of receiving either an experimental antidepressant medication or placebo. In actuality, all participants received placebo. Participants randomly assigned to receive the PCRS (n = 70) reported significantly smaller reductions (i.e., less placebo response) in depression than those who did not receive the PCRS (n = 67). The magnitude of this effect was medium (Cohen’s d = 0.40) and was not significantly impacted by diagnostic status. The number of adverse events (i.e., nocebo effect) was also lower in the PCRS group, particularly in the first week of the study. These findings suggest that briefly educating participants about placebo response factors can help mitigate the large placebo response rates that are increasingly seen in failed CNS drug development programs.
Simultaneous evaluation of antioxidative serum profiles facilitates the diagnostic screening of autism spectrum disorder in under-6-year-old children
Authors: Hirayama Aki , Wakusawa Keisuke , Fujioka Toru , Iwata Keiko , Usui Noriyoshi , Kurita Daisuke , Kameno Yosuke , Wakuda Tomoyasu , Takagai Shu , Hirai Takaharu , Nara Takahiro , Ito Hiromu , Nagano Yumiko , Oowada Shigeru , Tsujii Masatsugu , Tsuchiya Kenji J. , Matsuzaki Hideo 
Published: November 2020

AbstractThis case–control study aimed to assess oxidative stress alterations in autism spectrum disorder (ASD). We used the MULTIS method, an electron spin resonance-based technique measuring multiple free radical scavenging activities simultaneously, in combination with conventional oxidative stress markers to investigate the ability of this MULTIS approach as a non-behavioural diagnostic tool for children with ASD. Serum samples of 39 children with ASD and 58 age-matched children with typical development were analysed. The ASD group showed decreased hydroxyl radical (·OH) and singlet oxygen scavenging activity with increased serum coenzyme Q10 oxidation rate, indicating a prooxidative tendency in ASD. By contrast, scavenging activities against superoxide (O2·−) and alkoxyl radical (RO·) were increased in the ASD group suggesting antioxidative shifts. In the subgroup analysis of 6-year-olds or younger, the combination of ·OH, O2·−, and RO· scavenging activities predicted ASD with high odds ratio (50.4), positive likelihood (12.6), and percentage of correct classification (87.0%). Our results indicate that oxidative stress in children with ASD is not simply elevated but rather shows a compensatory shift. MULTIS measurements may serve as a very powerful non-behavioural tool for the diagnosis of ASD in children.