bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effects of Displacing Sedentary Behavior With Two Distinct Patterns of Light Activity on Health Outcomes in Older Adults (Implications for COVID-19 Quarantine)
Authors: Grant Dale , Tomlinson David , Tsintzas Kostas , Kolić Petra , Onambele-Pearson Gladys Leopoldine 
Published: December 2020

Rationale: The COVID-19 pandemic is limiting outdoor and community-based activities, especially for older adults owing to the requirement for self-isolation, potentially increasing prolonged sedentary behavior (SB). Given a poor tolerance for intense exercise, SB displacement with light intensity physical activity (LIPA) is a promising health enhancing alternative. Therefore, the aims of this study were to investigate the effects of two different types of SB displacement on health outcomes in older adults and any differential impact of associated LIPA pattern.Method: 28 older women (age: 73 ± 5 years, height: 1.60 ± 0.07 m, weight: 67 ± 10 kg, and BMI: 26.1 ± 3.6 kg/m2) underwent overnight fasted dual energy x-ray absorptiometry (DEXA) imaging, blood sampling, and functional assessments before being randomly allocated to one of two groups: (1) single continuous bout of 45–50 min LIPA daily (n = 14); or (2) SB fragmentation (SBF; ~48 min LIPA daily, 2 min LIPA for every 30 min of SB; n = 14). Compliance was systematically monitored using tri-axial accelerometery. All measures were taken at weeks 0 and 8.Results: Physical behavior significantly altered (decreased SB/increased LIPA; p &lt; 0.05) and to a similar extent in both groups. We observed a significant reduction in serum triglycerides [p = 0.045, effect size (ɳp2) = 0.15; SBF: −0.26 ± 0.77 mmol/L, LIPA: −0.26 ± 0.51 mmol/L], improved 30 s sit-to-stand (STS) count (p = 0.002, ɳp2 = 0.32, 2 ± 3 STS) and speed (p = 0.009, ɳp2 = 0.35, −10 ± 33%), as well as increased average handgrip strength (p = 0.001, ɳp2 = 0.45, 6 ± 12%), and gait speed (p = 0.005, ɳp2 = 0.27, 0.09 ± 0.16 m/s) in both groups. Interestingly, SBF caused a greater increase in peak handgrip strength (8 ± 14%), compared to LIPA (2 ± 10%; p = 0.04, ɳp2 = 0.38).Conclusion: SB displacement induced significant improvements in fasting triglycerides, gait speed, as-well as STS endurance/speed in older women. Frequent vs. continuous SB displacement also caused greater increases in handgrip strength. While both SB displacement protocols display promise as efficacious home-based interventions for self-isolating older adults, our results would suggest a physical functioning advantage of the SBF protocol for certain outcomes.
Developing a Theory-Informed Smartphone App for Early Psychosis: Learning Points From a Multidisciplinary Collaboration
Authors: Berry Natalie , Machin Matthew , Ainsworth John , Berry Katherine , Edge Dawn , Haddock Gillian , Lewis Shon , Morris Rohan , Bucci Sandra 
Published: December 2020

Background: Actissist is a smartphone app designed to deliver an intervention grounded in cognitive behavior therapy for early psychosis. Actissist was developed by a multidisciplinary team of academics, clinicians, experts by experience and software engineers. Actissist has been tested in two trials, the first a proof-of-concept trial where Actissist was safe, acceptable and feasible, the second, a powered randomized controlled trial.Objective: This article describes how our multidisciplinary team designed and developed Actissist. This article describes: (i) how Actissist was informed by initial qualitative interviews and focus groups and an expert reference group; (ii) refinements made to the app based on ongoing user feedback; (iii) successes and challenges encountered; and (iv) learning points and recommendations for involving stakeholders in digital health interventions.Methods: Expert reference group meetings informed the development of Actissist and design of subsequent trials, which included individuals with lived experience of psychosis, clinicians, academics, computer scientists and software engineers. Person-centered stakeholder involvement was promoted using focus groups and qualitative interviews prior to the development of the app, which informed version one of Actissist. Interviews were carried out with participants who had used Actissist. Two further versions of Actissist were developed following additional rounds of testing.Results: Multidisciplinary working throughout the Actissist project led to the development, inclusion and improvement of the app design and content. These changes and features included non-directive and compassionate content, co-designed recovery videos, relaxation exercises, psychoeducation material, ability to “favorite” areas of the app that users found helpful, and goal-setting. Challenges to collaborative working included discrepancies between what stakeholders want and what is technically possible to deliver, resource pressures, trying to deliver desired features within the boundaries of fundamental trial design considerations, and power imbalances associated with multidisciplinary working.Conclusions: The involvement of stakeholders in the design and development and delivery of Actissist has been fundamental to our development approach. Through this collaborative process, we have identified different perspectives and ideas that would have not been generated by the research team alone.Clinical Trial Registrations: Proof-of-concept trial: http://www.isrctn.com/ISRCTN34966555Fully-powered randomized controlled trial: https://www.isrctn.com/ISRCTN76986679
Prevalence of erectile dysfunction in male survivors of cancer: a systematic review and meta-analysis of cross-sectional studies
Authors: Pizzol Damiano , Xiao Tao , Smith Lee , Sánchez Guillermo F López , Garolla Andrea , Parris Christopher , Barnett Yvonne , Ilie Petre Cristian , Soysal Pinar , Shin Jae Il , Tully Mark A , Yang Lin , Veronese Nicola , Grabovac Igor 
Published: December 2020

BackgroundPrevalence of erectile dysfunction (ED) in male survivors of cancer across cancer types has not been systematically analysed.AimTo estimate the prevalence of ED in all types of cancer and identify characteristics associated with ED in survivors of cancer.Design and settingSystematic review and meta-analysis (MA) of cross-sectional studies.MethodMEDLINE, CINAHL, PsycINFO, and EMBASE were searched, targeting reports published from inception to 1 February 2020. All retrospective or prospective studies reporting prevalence of ED in male patients with cancer and using a validated tool for detection of ED were included. A random-effects MA model was used to pool prevalence of ED as absolute estimates at three different stages, that is, ‘healthy’, ‘at diagnosis’, and ‘after treatment’. A univariate MA regression including the three-level group variable as the only independent variable was used to assess the difference in ED prevalence across the three groups. Further MAs were conducted for studies involving patients at diagnosis and after treatment, and statistical inferences were made with setting for multiple testing controlling for a false discovery rate (FDR) <0.05.ResultsIn total, 1301 studies were assessed for inclusion. Of these, 141 were potentially eligible and subsequently scrutinised in full text. Finally, 43 studies were included with a total of 13 148 participants. Overall, pooled data of the included studies showed an ED prevalence of 40.72% (95% confidence interval [CI] = 31.80 to 50.29) in patients with cancer, with prevalences of 28.60% (95% CI = 12.10 to 53.83) at time of diagnosis and 42.70% (95% CI = 32.97 to 53.03) after treatment, with significant difference between these two stages and across cancer locations, controlling for an FDR <0.05.ConclusionErectile dysfunction was particularly high in male survivors of cancer and was associated with cancer treatment, cancer site, and age.
Advantages and disadvantages of femoral port systems in hematоlogical patients with superior vena cava syndrome
Authors: Galstyan G. M. , Spirin M. V. , Drokov M. Yu. , Kostina I. E. , Mangasarova Ya. K. 
Published: December 2020

Background. In the superior vena cava syndrome, vein catheterisation provides an alternative for vascular access. Few reports describe the usage of femoral ports.Aim. Description of pros and contras for femoral port installation in patients with haematological malignancies and the superior vena cava syndrome.Materials and methods. This prospective non-randomised, single-centre study included 163 haematological patients implanted 72 ports in superior vena cava, 35 — in inferior vena cava and inserted with 156 non-tunnelled femoral catheters. Catheterisation properties, complications, duration of use and reasons for port and catheter removal were registered.Results. No signiﬁcant differences were observed between ports in superior and inferior vena cava as per the frequency of urokinase use in catheter dysfunction, catheter dislocation, catheter-associated bloodstream and pocket infections. Differences were revealed in the catheter-associated thrombosis rate, which was higher with femoral access (17.0 % or 0.9/1000 catheter days vs. 8.3 % or 0.2/1000 catheter days, p = 0.017). Ports in inferior vena cava had a lesser duration of use than in superior vena cava (p = 0.0001). Unlike femoral ports, non-tunnelled femoral catheters had higher rates of catheter-associated thrombosis (9/1000 vs. 0.9/1000 catheter days, p = 0.002) and infection (4.9/1000 vs. 0.3/1000 catheter days, p = 0.002). One lymphoma therapy course required one femoral port or 1 to 14 (median 3) non-tunnelled femoral catheters.Conclusion. Femoral port implantation is a necessary measure in patients with the superior vena cava syndrome. It has advantages in terms of catheterisation frequency, lower infectious and thrombotic complication rates compared to non-tunnelled femoral catheters.
First experience of allogeneic haematopoietic stem cell transplantation in patients with mantle cell lymphoma with a mutation in the <i>TP53</i> gene
Authors: Koroleva D. A. , Gabeeva N. G. , Drokov M. Yu. , Vasilyeva V. A. , Biderman B. V. , Tsygankova S. V. , Bulygina E. S. , Galstyan G. M. , Sudarikov A. B. , Obukhova T. N. , Kuzmina L. A. , Zvonkov E. E. , Parovichnikova E. N. , Savchenko V. G. 
Published: December 2020

Introduction. Mutations in the TP53 gene in patients with mantle cell lymphoma (MCL TP53+) are associated with a low response to intensive chemotherapy (CT) and adverse outcomes. Allogeneic haematopoietic stem cells transplantation (allo-HSCT) is a curative approach in MCL-TP53+ patients.Aim. Efﬁcacy and safety assessment of allo-HSCT in MCL-TP53+ patients.Main ﬁndings. During 2016–2020, allo-HSCT in MCL TP53+ was performed in three patients. Two of them were grafted from HLA-identical unrelated donors, and one — from a haploidentical donor. Pre-transplant conditioning was “ﬂudarabine + treosulfan + melphalan” in one case, and “ﬂudarabine + busulfan” — in the other two. In three patients, leukocyte and platelet counts were recovered at days +18 and +20, +17 and +21, +19 and +16 after allo-HSCT, respectively. Acute graft-versushost disease (aGVHD) was observed in all patients (grade I — in 2 patients, grade IV — in 1 patient). One patient developed chronic GVHD (cGVHD) of moderate grade. All three patients exhibited complete remission and 100% donor chimerism in allo-HSCT follow-up of 6, 15 and 40 months, respectively.
Obstructive Sleep Apnea (OSA) dan Hubungannya dengan Defisiensi Vitamin D
Authors: Algifary Dandy Fahsi 
Published: December 2020

Diperkirakan sebanyak 2-4% dari total populasi paruh baya menderita apnea tidur, dengan kecenderungan pada pria dibandingkan dengan wanita. Efek jangka panjang Obstructive Sleep Apnea (OSA) antara lain gangguan fungsi kognitif, resistensi insulin, penyakit kardiovaskular, dan depresi. Penelitian mengenai hubungan antara vitamin D dan keparahan OSA telah menjadi perhatian penting karena kekurangan vitamin D juga menjadi masalah medis yang umum di seluruh dunia, dan prevalensinya meningkat seiring dengan obesitas, gaya hidup yang tidak banyak bergerak, paparan sinar matahari yang terbatas, dan penuaan. Tujuan dari studi literatur ini adalah untuk mengetahui hubungan antara OSA dan dengan adanya defisiensi Vitamin D. Sumber pustaka yang digunakan dalam studi literatur ini melibatkan 17 pustaka yang berasal dari 1 jurnal nasional dan 16 jurnal internasional. Berbagai penelitian menunjukkan adanya hubungan antara defisiensi vitamin D dan OSA yang disebabkan oleh mekanisme patogenetik yang kompleks dan dipengaruhi oleh beberapa faktor perancu. Pasien dengan OSA yang parah secara umum berkaitan dengan kekurangan vitamin D.
Hubungan Antara Rhinitis Alergi Dengan Sinusitis Pada Pemeriksaan Foto Sinus Paranasal di RSUD DR. H. Abdul Moeloek Bandar Lampung Tahun 2019
Authors: Hapsari Tantri Dwi Kaniya Retno , Wulandari Mardheni , Haryadi Haryadi , Sabilla Salma Restiany 
Published: December 2020

Background: Sinusitis and rhinitis are closely related diseases, especially chronic rhinitis. Allergic rhinitis is an allergic reaction to the nose that exposed to allergens. Sinusitis is an inflammatory disease that occurs in the sinus mucosa caused by inflammation of the nose with symptoms in the form of nasal congestion and pressure in the infected sinus area.
Purpose: This study aims to determine whether there is a relationship between Allergic Rhinitis and Sinusitis on Paranasal Sinus Photo Examination at RSUD DR. H. Abdul Moeloek Bandar Lampung in 2019.
Research Method: The research method used in this study is a descriptive analytic study with a cross sectional approach because it intends to analyze the influence or relationship in the study. The research design is cross sectional, which is a type of research conducted by collecting data only once at a time.
The result: By using the Chi Square test, it shows a p-value = 0.000 which is less than the significance value of 5% (0.05), this shows that there is a significant relationship between allergic rhinitis and sinusitis. From the above analysis, it was found that the OR value = 17.28, which states that patients who experience allergic rhinitis have 17.28 times to experience sinusitis. By using the Chi Square test, it shows a p-value = 0.000 which is less than the significance value of 5% (0.05), this shows that there is a significant relationship between allergic rhinitis and sinusitis.
Conclusion: There is a significant relationship between allergic rhinitis and sinusitis on the paranasal sinus photo examination at RSUD DR. H. Abdul Moeloek Bandar Lampung in 2019.
Territoriality and Space Among the Hupd'ah and Tukano of the River Uaupés Basin
Authors: Athias Renato 
Published: December 2020

Short description (adapted from the Text):
The aim of this text is to present a vision of the territorial occupation of the indigenous groups that live in the Uaupés Basin, focusing on inter-ethnic relations and the models of spatial occupation of the Maku and Tukanoan (Oriental) indigenous groups that inhabit this region. The idea of this exercise is to indicate elements for a possible analysis of the concept of territoriality used by the Indians that live in this region. The basic of this work is the hypotheses on the indigenous presence in the Uaupés basin, presented by Nimuendajú and which an, albeit with a number reservations, accepted by the majority of the anthropologists working in this part of the Amazon. Ideally, archeological studies would be made to prove these hypotheses, but both the mythology and the oral tradition of these populations appear to ratify them. (…)
Fast Parameter Estimation of Binary Mergers for Multimessenger Follow-up
Authors: Finstad Daniel , Brown Duncan A. 
Published: December 2020

Abstract
Significant human and observational resources have been dedicated to electromagnetic follow-up of gravitational-wave events detected by Advanced LIGO and Virgo. As the sensitivity of LIGO and Virgo improves, the rate of sources detected will increase. Margalit & Metzger (2019) have suggested that it may be necessary to prioritize observations of future events. Optimal prioritization requires a rapid measurement of a gravitational-wave event’s masses and spins, as these can determine the nature of any electromagnetic emission. We extend the relative binning method of Cornish (2013) and Zackay et al. (2018) to a coherent detector-network statistic. We show that the method can be seeded from the output of a matched-filter search and used in a Bayesian parameter measurement framework to produce marginalized posterior probability densities for the source’s parameters within 20 minutes of detection on 32 CPU cores. We demonstrate that this algorithm produces unbiased estimates of the parameters with the same accuracy as running parameter estimation using the standard gravitational-wave likelihood. We encourage the adoption of this method in future LIGO–Virgo observing runs to allow fast dissemination of the parameters of detected events so that the observing community can make best use of its resources.
EcoBank: A flexible database platform for sharing ecological data
Authors: Kim Hyun Woo , Yoon Sungsoo , Kim Mokyoung , Shin Manseok , Yoon Heenam , Kim Kidong 
Published: December 2020

Environmental crisis challenges the human race harder than ever before. Ecologists have produced a massive amount of data to cope with the crisis. Accordingly, many national scale ecological database systems have been developed worldwide to manage and analyze these datasets. However, in Korea, ecological datasets produced by different research institutes for different purposes have not been integrated or serviced due to the lack of a well-designed information infrastructure. To address this obstacle, we present EcoBank (www.nie-ecobank.kr), an open, web-based ecological database platform designed to play an important role in ecosystem analysis not only in Korea but also worldwide.
The architecture of EcoBank comprises core technologies of WebGIS, Application Programming Interface (API), responsive web, and open-source software (OSS). Huge ecological datasets from 3 different sources, including the National Institute of Ecology (NIE) in Korea, related domestic and international platforms and repositories, pass through the three conceptual modules in EcoBank: data management, analysis, and service. Diverse potential stakeholders of EcoBank can be classified into three groups: researchers, policymakers, and public users. EcoBank aims to expand its horizons through mutual communication between these stakeholders. We opened and launched EcoBank service from December 2019, and now began to broaden its network by linking to other data platforms and repositories over the globe to find possible solutions to ecological issues in Korea.
La morale et le désir : sexualité, genre et inégalité en Chine contemporaine
Authors: Pettier Jean-Baptiste 
Published: December 2020

La période de réformes économiques qui s’est ouverte à partir des années 1980 en Chine a été associée de manière récurrente à la fois à une période de libération sexuelle et de réaffirmation des identités sexuées. Prostitution et pornographie ont gagné une place publique de plus en plus prégnante, par la généralisation de pratiques de corruption au service de décideurs masculins. Le débat public chinois a dans ce contexte produit une critique sévère de l’irréalisme des idéaux de l’ère maoïste, tout en s’inquiétant de l’occidentalisation supposée des nouvelles générations. Le point commun le plus notable à ces débats est le rejet du constructivisme par l’acceptation généralisée du désir sexuel, en particulier masculin, comme « besoin naturel ». Deux morales, l’une prônant la maîtrise du désir, l’autre son accomplissement, s’y opposent. Le discours qui s’est imposé situe ainsi la question du désir sexuel entre animalité et civilisation en le considérant à la fois comme normal et comme répréhensible, et en en faisant ainsi un enjeu de l’identité morale chinoise.
Le véritable amour : le dispositif de soupçon à l’égard des couples binationaux
Authors: Salcedo Robledo Manuela 
Published: December 2020

Depuis les années 2000, les couples binationaux sont confrontés au même problème – celui du droit au séjour du partenaire étranger. Certes, certains se trouvent dans des situations plus complexes que d’autres, mais ce qui les réunit, c’est d’être soumis aux règles de plus en plus restrictives de la politique d’immigration en France. Ils sont contraints de dévoiler leur vie personnelle devant les institutions des étrangers (préfecture, consulats et tribunaux) afin d’obtenir le droit au séjour du ressortissant étranger non européen, le plus souvent issu des pays dits du Sud. De ce dispositif sont produits des couples et des sujets « suspects » ou « vrais ». Les hommes étrangers se retrouvent ainsi soupçonnés d’emblée comme de potentiels « escrocs sentimentaux à but migratoire » tandis que les femmes françaises, surtout lorsqu’elles sont plus âgées que leur conjoint, sont susceptibles d’être jugées comme des victimes naïves, cumulant souvent des dissymétries conjugales qui seraient la preuve d’une fausse conjugalité. À partir des matériaux issus de ma thèse de doctorat et collectés auprès de couples binationaux de même sexe et de sexe différent, je propose d’analyser dans cet article la mise en place de ce dispositif de soupçon qui vise à trier, vérifier et juger la conjugalité de ces couples.
CHARACTERISTICS OF SLAG ACTIVATED PHC-PILE WITH REDUCED CEMENT CONTENT
Authors: Jang Hongseok , So Seungyoung 
Published: December 2020

ABSTRACT
Ground Granulated Blast-furnace Slag (GGBS) powders, the massive by-products produced in the process of manufacturing cast iron are actively used as a substitute for cement, one of the major causes of greenhouse gas emissions. The purpose of this study was to investigate the proper mixing ratio of the activator, and to reduce the usage of cement in the production of high-strength steam cured concrete using GGBS. The cured products of various ratio were analyzed by XRD and TG/DTA, and the best ratio of the cured product were applied to the Pre-stressed high-strength concrete (PHC) Pile, and the performance was then evaluated. The results showed that the fluidity was improved by mixing with GGBS, and when an appropriate amount of activator was used, it was possible to produce high-strength cured products. In the PHC-Pile test, the replacement rate of 40% GGBS and combined 4% anhydrite gypsum and 2% Ca(OH)2 as an activator was excellent. The compressive strength (2MPa more), shear strength (1.3MPa more), and Axial force strength (2.7Mpa more) were more improved than for the normal Portland cement PHC-Pile, and this GGBS pile can be manufactured more economically (the cost can be saved in the amount of 14.5%). This is caused by the activating agent destroying the glassy film of the GGBS, and actively inducing the pozzolanic reaction, so that the hydrate materials are generated, such as C–S–H. In addition, by positively utilizing the inexpensive industrial by-product, GGBS, it is possible to manufacture environmentally friendly concrete products, while reducing the amount of cement used.