bluuebunny/crossref_metadata_2025_split huggingface dataset:
EDUCAÇÃO ANTIRRACISTA? UMA ANÁLISE NOS PERIÓDICOS DE EDUCAÇÃO FÍSICA (2014 a 2020)
Authors: Germano Vitor Abdias Cabót , Soares Dandara de Carvalho 
Published: December 2020

A lei 10.639/03 estabelece a obrigatoriedade do estudo da História e cultura africana e afro-brasileira no Ensino Fundamental e Médio, o que inclui a Educação Física. Deste modo, o objetivo deste estudo foi realizar um levantamento das publicações sobre as questões étnico-raciais nos principais periódicos de Educação Física escolar, bem como analisar as pesquisas relacionadas à aplicabilidade da lei 10639/03. Para isto, a partir de uma revisão bibliográfica, este estudo analisou os artigos de seis revistas de Educação Física, entre o período de 2014 a 2020. Foram encontrados 37 artigos que abordam questões relativas à cultura negra, representando 1,3% do total de publicações. Já em relação ao ambiente escolar, esse percentual cai para 0,4%. Assim, pode-se dizer que essa temática é praticamente invisível nos periódicos. Evidenciou-se, portanto, a necessidade de avanços na tentativa de uma transformação deste cenário, buscando unir esforços na promoção de uma educação antirracista.
Phytochemical and Biological Investigation of Stevia rebaudiana (Bert.) Leaves Grown in Bangladesh
Authors: Sultana Chand , Azad Md AK , Rahman Md Mominur , Muhit Md Abdul , Rahman SM Abdur 
Published: December 2020

Three fractions obtained by Kupchan partitioning of 70% methanol extract of leaves of Stevia rebaudiana with n-hexane, dichloromethane and ethyl acetate designated by HSR, DSR and ESR were investigated for their antioxidant and antimicrobial activities. HSR and ESR exhibited prominent free radical scavenging activity having IC50 value of 11.59 and 10.38 μg/ml compared to standard, ascorbic acid (IC50 value 6.05 μg/ml). HSR and ESR also demonstrated significant antibacterial activity by disc diffusion method on some Gram-positive and Gramnegative bacteria. Among the fractions ESR showed the highest antioxidant and antibacterial activity. No significant antifungal activity was observed for any fraction. Preliminary phytochemical screening of all fractions showed the presence of alkaloids, saponin, flavonoids, tannin, carbohydrate and triterpenoids. Total three compounds have been isolated from ESR fraction among which two known compounds (1-2) were characterized as quercitrin (1) and physcion (2) through 1D NMR spectroscopic technique and other one could be a 9,10- anthraquinone derivative which was not characterized yet. The compound physcion (2) is first time report from the plant Stevia rebaudiana.
Dhaka Univ. J. Pharm. Sci. 19(2): 191-197, 2020 (December)
Six Immune Associated Genes Construct Prognostic Model Evaluate Low-Grade Glioma
Authors: Tan Yin Qiu , Li Yun Tao , Yan Teng Feng , Xu Yang , Liu Bao Hui , Yang Ji An , Yang Xue , Chen Qian Xue , Zhang Hong Bo 
Published: December 2020

BackgroundThe immunotherapy of Glioma has always been a research hotspot. Although tumor associated microglia/macrophages (TAMs) proves to be important in glioma progression and drug resistance, our knowledge about how TAMs influence glioma remains unclear. The relationship between glioma and TAMs still needs further study.MethodsWe collected the data of TAMs in glioma from NCBI Gene Expression Omnibus (GEO) that included 20 glioma samples and 15 control samples from four datasets. Six genes were screened from the Differential Expression Gene through Gene ontology (GO) analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, protein–protein interaction (PPI) network and single-cell sequencing analysis. A risk score was then constructed based on the six genes and patients’ overall survival rates of 669 patients from The Cancer Genome Atlas (TCGA). The efficacy of the risk score in prognosis and prediction was verified in Chinese Glioma Genome Atlas (CGGA).ResultsSix genes, including CD163, FPR3, LPAR5, P2ry12, PLAUR, SIGLEC1, that participate in signal transduction and plasma membrane were selected. Half of them, like CD163, FPR3, SIGLEC1, were mainly expression in M2 macrophages. FPR3 and SIGLEC1 were high expression genes in glioma associated with grades and IDH status. The overall survival rates of the high risk score group was significantly lower than that of the low risk score group, especially in LGG.ConclusionJoint usage of the 6 candidate genes may be an effective method to diagnose and evaluate the prognosis of glioma, especially in Low-grade glioma (LGG).
3D Heads-Up Display vs. Standard Operating Microscope Vitrectomy for Rhegmatogenous Retinal Detachment
Authors: Asani Ben , Siedlecki Jakob , Schworm Benedikt , Mayer Wolfgang J. , Kreutzer Thomas C. , Luft Nikolaus , Priglinger Siegfried G. 
Published: December 2020

Purpose: To assess the efficacy and outcomes of 23-gauge vitreoretinal surgery for rhegmatogenous retinal detachment using a three-dimensional heads-up display (3D HUD) surgical platform as compared to a standard operating microscope (SOM) setting.Design: Retrospective cohort study.Participants: One hundred and forty consecutive eyes of 140 patients with primary retinal detachment.Methods: All eyes underwent 23-gauge pars plana vitrectomy for primary retinal detachment using either a 3D HUD (NGENUITY; Alcon Inc., Fort Worth, Texas, USA; n = 70 eyes) or a SOM setting (n = 70 eyes); in cases of significant cataract, additional phacoemulsification with intraocular lens (IOL) implantation was performed. Minimum follow-up was 2 months.Main Outcome Measures: Primary retinal reattachment rate, rate of proliferative vitreoretinopathy (PVR), best-corrected visual acuity (BCVA), and duration of surgery.Results: There were 70 eyes each in the 3D HUD and the SOM group. Both groups did not differ concerning age (p = 0.70), extent of retinal detachment (p = 0.07), number of retinal tears (p = 0.40), macular involvement (p = 0.99), and preoperative BCVA (p = 0.99). Postoperatively, 3D HUD and SOM were comparable concerning the primary retinal reattachment rate (88.6 vs. 94.3%; p = 0.37), the development of postoperative PVR (12.9% vs. 7.1%; p = 0.40) and final BCVA (0.26 ± 0.40 vs. 0.21 ± 0.38 logMAR; p = 0.99). Duration of surgery was significantly longer in the 3D HUD group (66.2 ± 16.5 vs. 61.2 ± 17.1 min; p = 0.04), an effect which however vanished after a “learning curve” of the first 35 eyes (p = 0.49).Conclusions: On par results to a conventional operating microscope can be achieved with a 3D HUD setting when performing 23-gauge vitreoretinal surgery for rhegmatogenous retinal detachment, including the primary retinal reattachment rate, the incidence of postoperative PVR and final BCVA. However, duration of surgery might initially be slightly longer with 3D HUD, suggesting the effect of a learning curve.
Subjective Sleep Quality in Amnestic Mild Cognitive Impairment Elderly and Its Possible Relationship With Plasma Amyloid-β
Authors: Liu Yajing , Chen Lushi , Huang Shuyun , Zhang Chengguo , Lv Zeping , Luo Jiali , Shang Pan , Wang Yukai , Xie Haiqun 
Published: December 2020

Study objectivesTo investigate the extent to which sleep quality associated with plasma Aβ levels in amnestic mild cognitive impairment (aMCI) elderly.MethodsA total of 172 cognitively normal (NC) elderly and 133 aMCI elderly were included in this study. For the evaluation of sleep quality, the Pittsburgh Sleep Quality Index (PSQI) was used. Levels of plasma Aβ were determined by the sandwich enzyme-linked immunosorbent assay technique. Multivariable linear regression analysis was applied to evaluate associations between sleep quality and plasma Aβ levels after adjusting potential confounders.ResultsCompared to NC subjects, participants with aMCI had a higher global PSQI score (8.72 ± 3.87 vs. 7.10 ± 3.07, p &lt; 0.001). The global PSQI score was positively associated with plasma Aβ42 level in the aMCI group (β = 0.063, 95% CI 0.001–0.125, and p = 0.049) but not in the NC group (p &gt; 0.05). Additionally, a higher global PSQI score was associated with a higher plasma Aβ42/Aβ40 ratio in both NC (β = 0.010, 95% CI 0.003–0.016, and p = 0.003) and aMCI groups (β = 0.012, 95% CI 0.005–0.018, and p &lt; 0.001). The association between global PSQI score and plasma Aβ42/Aβ40 ratio was stronger in individuals with aMCI relative to the NC subjects (β = 0.076 vs. 0.030, p for interaction = 0.023).ConclusionPoor sleep quality was associated with plasma Aβ42 and Aβ42/Aβ40 ratio, with a stronger effect among individuals with aMCI. A better understanding of the role of sleep in plasma Aβ levels in aMCI patients could lead to effective sleep-based intervention against the risk of Alzheimer’s disease.
Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NFκB Axis
Authors: Eid Basma G. , Abdel-Naim Ashraf B. 
Published: December 2020

Benign prostatic hyperplasia (BPH) is a serious illness affecting middle-aged and elderly male patients. It is a complication of several diseases including metabolic syndrome. BPH has been associated with inflammation and increased oxidative stress in prostatic tissues. Piceatannol (PIC) is an active natural polyhydroxylated stilbene found in many plants. It has profound anti-inflammatory as well as antioxidant activities. However, it suffers relatively poor pharmacokinetic properties. Nanoformulation is an acknowledged approach to improve PIC bioavailability. The goal was to evaluate the ability of PIC in preventing testosterone-induced benign prostatic hyperplasia in rats. PIC was prepared in a self-nanoemulsifying drug delivery system (SNEDDS). Animals were placed into seven groups: 1) control (vehicle), 2) PIC SNEDDS (20 mg/kg), 3) testosterone (3 mg/kg), 4) testosterone + PIC SNEDDS (5 mg/kg), 5) testosterone + PIC (10 mg/kg), 6) testosterone + PIC SNEDDS (20 mg/kg) and 7) testosterone + finasteride (5 mg/kg). Testosterone was injected SC while PIC SNEDDS and finasteride were given orally. All treatments were given once daily, 5 days/week for four consecutive weeks. PIC administration ameliorated increased prostate weights and indices in addition to histopathological alterations. Further it inhibited accumulation of lipid peroxidation, depletion of glutathione (GSH) and exhaustion of catalase (CAT). PIC SNEDDS exhibited anti-proliferative activities as demonstrated by the inhibition of cyclin D1 protein expression and Bcl2 mRNA expression in addition to enhancement of Bax mRNA expression and caspase-3 content. Immunohistochemically, PIC SNEDDS protected against the testosterone-induced increased expression of tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), nuclear factor kappa B (NFκB) and also offered protection against the decline in Nrf2 expression. Further, a significant enhancement of Nfe212 and Homx1 mRNA expression was detected in PIC SNEDDS-treated animals in comparison to the testosterone group. Conclusively, PIC prepared in SNEDDS protects against experimentally induced BPH via modulation of, at least partly, Nrf2/HO-1/NFκB axis.
Parental Cognitions About Sleep Problems in Infants: A Systematic Review
Authors: Knappe Susanne , Pfarr Anna-Lisa , Petzoldt Johanna , Härtling Samia , Martini Julia 
Published: December 2020

Introduction:Parental cognitions may directly and indirectly contribute to infant sleep outcomes. This review provides a systematic up-to-date overview of the associations between parental cognitions and infant sleep problems with special emphasis on temporal relationships and the content of parental cognitions.Methods:A systematic literature research in PubMed and Web of Science Core Collection sensu Liberati and PRISMA guidelines was carried out in March 2020 using the search terms (parent*AND infant*AND sleep*problem*), including studies with correlational or control group designs investigating associations between parental cognitions and sleep problems in children aged 1–6 years.Results:Twenty-three studies (published from 1985 to 2016) met inclusion criteria, of which 14 reported group differences or associations between parental sleep-related cognitions and child sleep outcomes. Nine papers additionally reported on the role of general parental child-related cognitions not directly pertaining to sleep. Findings from longitudinal studies suggest that parental cognitions often preceded child sleep problems. Cognitions pertaining to difficulties with limit-setting were especially prevalent in parents of poor sleepers and were positively associated with both subjective and objective measures of child sleep outcomes.Conclusions:Parental cognitions appear to play a pivotal role for the development and maintenance of sleep problems in young children, arguing that parents' attitudes and beliefs regarding child sleep inadvertently prompts parental behavior toward adverse sleep in offspring. Associations are however based on maternal reports and small to moderate effect sizes. Thus, additional parental factors such as mental health or self-efficacy, as well as additional offspring factors including temperamental dispositions and regulatory abilities, require consideration in further studies.
Referendum del 12-13 giugno 2011 a Roma: la campagna e la partecipazione
Authors: Cedroni Lorella , De Rosa Roberto , D'Amelio Nicola 
Published: December 2020

Il Comune di Roma e i suoi Municipi
Territorio, comunicazione e mobilitazione
La campagna referendaria Municipio per Municipio
La partecipazione a Roma nelle elezioni e nei referendum
La partecipazione nel referendum del 12-13 giugno
Psicologia do esporte: reflexões científicas sobre o continuum energético bipolar corpo-mente: uma resenha do livro "Corpo e Movimento" de Olavo Feijó
Authors: Martins Lilian 
Published: December 2020

Introdução: A Psicologia do Esporte é uma ciência em constante evolução e conhecer seus princípios basilares pode contribuir para maior compreensão dos fenômenos envolvidos.
Objetivo: Recuperar e destacar aspectos importantes da Psicologia do Esporte identificados em suas origens.
Desenvolvimento: Foi desenvolvida uma resenha descritiva da obra original, que procura apresentar a Teoria do Contínuo Energético Bipolar – o continuum de energia corpo-mente proposta pelo autor.
Conclusão: Foram recuperados e destacados aspectos importantes da Psicologia do Esporte que podem esclarecer e complementar o conhecimento no tema aos interessados: psicólogos, treinadores, atletas e demais integrantes de equipes técnicas esportivas. Considerou-se a obra uma leitura basilar no tema abordado. A Psicologia do Esporte preocupa-se tanto com o desempenho esportivo quanto à saúde e bem-estar do atleta e tais princípios devem, também, ser aplicados nas aulas de Educação Física a fim de favorecer o desenvolvimento integral dos alunos.
Joan Timoneda, Rosas de romances. Volumen II. Rosa de Amores. Rosa Gentil [1573], edición facsímil y estudio de Vicenç Beltran. México D. F., Frente de Afirmación Hispanista, A. C., 2020
Authors: Pla Colomer Francisco Pedro 
Published: December 2020

Reseña de: Joan Timoneda, Rosas de romances. Volumen II. Rosa de Amores. Rosa Gentil [1573], edición facsímil y estudio de Vicenç Beltran. México D. F., Frente de Afirmación Hispanista, A. C., 2020
Childhood bullous systemic lupus erythematosus
Authors: Gharib Khaled 
Published: December 2020

Background
Bullous systemic lupus erythematosus (BSLE) has rarely been described in pediatric lupus population, and the real prevalence of childhood-onset BSLE has not been reported.
BSLE is a rare manifestation of systemic lupus erythematosus and is very rare in children. BSLE affects women more often than men, reflecting the female preponderance in systemic lupus erythematosus. It most often manifests in the second through fourth decades of life, but it has also been reported in children and older adults.

Patients and methods
Herein, we describe a case of a 10-year-old female patient who presented with a 1-year history of recurrent itchy urticated skin eruption, which was followed 2 months later (after the first year) by a generalized blistering eruption with photosensitivity.

Results
Histopathologic examination revealed a subepidermal blister and papillary-tip neutrophil microabscesses. Immunofluorescence studies showed linear immunoglobulin G (IgG) and IgC deposition along the BMZ with weaker staining of IgA and IgM. Laboratory tests revealed positive ANA, dsDNA, anti-SM antibodies, elevated erythrocyte sedimentation rate, and proteinuria.

Conclusion
Although the course of BSLE is often remitting, but not in our case, treatment with dapsone is successful in most cases of BSLE.
Alternativas epistemológicas para o design da informação: a forma enquanto conteúdo | Epistemological alternatives for information design: form as content
Authors: Souza Eduardo Antonio , Oliveira Gabriela Araujo , Miranda Eva Rolim , Coutinho Solange Galvão , Waechter Hans Da Nóbrega , Porto Filho Gentil 
Published: December 2020

A partir da revisão bibliográfica, delineamos quatro categorias de definições de design da informação que evidenciam princípios fundamentais para o campo. Encontramos que o design da informação define-se como uma atividade de mediação por excelência, buscando, de maneira ideal, tornar-se transparente para a apreensão de um dado por um usuário. Associando teoria à história do design, argumentamos que essa perspectiva epistemológica deriva de uma visão moderna de mundo que se reflete em opções estéticas que não se reconhecem como tal – um paradigma contradito pela corrente do pós-modernismo crítico da escola de Cranbrook. Por fim, argumentamos através de conceitos de Vilém Flusser que a forma no design não consiste apenas de escolhas estilísticas, mas de reflexos de modelos que estruturam a realidade, possibilitando alternativas epistemológicas para a prática.After reviewing the literature, we proposed four categories to organize definitions of information design, each of which highlights fundamental principles for the practice. We found that information design defines itself as an activity of mediation per excellence, looking forward to ultimately become a transparent treatment of the data towards the user. By relating design theory to its history, we argue that this epistemological view comes from a modern worldview and unfolds as aesthetic choices that are not recognized as such – a paradigm that critical post-modernism form Cranbrook school argued against. At last, using concepts from Vilém Flusser we argue that form in design is not just about stylistic choices, but reflects models that structure reality, finally providing epistemological alternatives for the practice.
A cultivated planet in 2010 – Part 2: The global gridded agricultural-production maps
Authors: Yu Qiangyi , You Liangzhi , Wood-Sichra Ulrike , Ru Yating , Joglekar Alison K. B. , Fritz Steffen , Xiong Wei , Lu Miao , Wu Wenbin , Yang Peng 
Published: December 2020

Abstract. Data on global agricultural production are usually
available as statistics at administrative units, which does not give any
diversity and spatial patterns; thus they are less informative for subsequent
spatially explicit agricultural and environmental analyses. In the second
part of the two-paper series, we introduce SPAM2010 – the latest global
spatially explicit datasets on agricultural production circa 2010 – and
elaborate on the improvement of the SPAM (Spatial Production Allocation
Model) dataset family since 2000. SPAM2010 adds further methodological
and data enhancements to the available crop downscaling modeling, which
mainly include the update of base year, the extension of crop list, and the
expansion of subnational administrative-unit coverage. Specifically, it not
only applies the latest global synergy cropland layer (see Lu et al.,
submitted to the current journal) and other relevant data but also expands
the estimates of crop area, yield, and production from 20 to 42 major crops
under four farming systems across a global 5 arcmin grid. All the SPAM
maps are freely available at the MapSPAM website (http://mapspam.info/, last access: 11 December 2020),
which not only acts as a tool for validating and improving the performance
of the SPAM maps by collecting feedback from users but is also a
platform providing archived global agricultural-production maps for better
targeting the Sustainable Development Goals. In particular, SPAM2010 can be
downloaded via an open-data repository (DOI: https://doi.org/10.7910/DVN/PRFF8V; IFPRI, 2019).
Inequality-constrained free-surface evolution in a full Stokes ice flow model (evolve_glacier v1.1)
Authors: Wirbel Anna , Jarosch Alexander Helmut 
Published: December 2020

Abstract. Like any gravitationally driven flow that is not constrained at the upper surface, glaciers and ice sheets feature a free surface, which becomes a free-boundary problem within simulations.
A kinematic boundary condition is often used to describe the evolution of this free surface.
However, in the case of glaciers and ice sheets, the naturally occurring constraint that the ice surface elevation (S) cannot fall below the bed topography (B) (S-B≥0), in combination with a non-zero mass balance rate complicates the matter substantially.
We present an open-source numerical simulation framework to simulate the free-surface evolution of glaciers that directly incorporates this natural constraint.
It is based on the finite-element software package FEniCS solving the Stokes equations for ice flow and a suitable transport equation, i.e. “kinematic boundary condition”, for the free-surface evolution.
The evolution of the free surface is treated as a variational inequality, constrained by the bedrock underlying the glacier or the topography of the surrounding ground.
This problem is solved using a “reduced space” method, where a Newton line search is performed on a subset of the problem (Benson and Munson, 2006).
Therefore, the “constrained” non-linear problem-solving capabilities of PETSc's (Portable, Extensible Toolkit for Scientific Computation, Balay et al., 2019) SNES (Scalable Non-linear Equations Solver) interface are used.
As the constraint is considered in the solving process, this approach does not require any ad hoc post-processing steps to enforce non-negativity of ice thickness and corresponding mass conservation.
The simulation framework provides the possibility to divide the computational domain into different subdomains so that individual forms of the relevant equations can be solved for different subdomains all at once.
In the presented setup, this is used to distinguish between glacierised and ice-free regions.
The option to chose different time discretisations, spatial stabilisation schemes and adaptive mesh refinement make it a versatile tool for glaciological applications. We present a set of benchmark tests that highlight that the simulation framework is able to reproduce the free-surface evolution of complex geometries under different conditions for which it is mass-conserving and numerically stable.
Real-world glacier examples demonstrate high-resolution change in glacier geometry due to fully resolved 3D velocities and spatially variable mass balance rate, whereby realistic glacier recession and advance states can be simulated.
Additionally, we provide a thorough analysis of different spatial stabilisation techniques as well as time discretisation methods.
We discuss their applicability and suitability for different glaciological applications.