bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Extended Transit and Temperature Variations on EID50 Values of Thermostable NDVI-2 Vaccines
Authors: Egbuji A. N. , Chukwuedo A. A. , Shedua L. N. , Gyallak J. K. , Swomen L. N. , Muhammad M. , Nwosuh C. I. , Enurah L. U. 
Published: October 2020

Temperature alterations due to poor cold keeping condition have consistently posed a challenge to vaccines dose EID50 titre value. The sensitivity of Newcastle disease vaccine to temperature variations due to poor cold storage condition in rural settings, led to the development of the NDVI-2 thermostable vaccine, which is known to exhibit a thermostability of 3 hours at 56 °C. In this study, three Newcastle disease vaccines (NDVI-2) with EID50 titre per dose values of log10 EID50 7.7, 7.6 and 6.75 respectively from vaccine production facility at the National Veterinary Research Institute (NVRI), Vom Nigeria, were sent for certification at African Union laboratory at Debre Zeit, Ethiopia under cold condition; using ice packs for cold chain maintenance. Tracking of the vaccine in the course of freight to the certifying laboratory revealed changes in the original transit route by the airline and delay by custom at the receiving country port. Thus, a 12 hours transit freight was delayed for over 7 days before arrival at the certifying laboratory. Though, the EID50 titre per dose values of these vaccines were originally well above recommended EID50 5.5 per dose value by log 2.2, log 2.1 and log 1.25 for NDVI-2 respectively. Comparing these vaccines EID50 values obtained from the certifying laboratory in relation to values initially obtained by the Quality Control Division of the producing Institute (NVRI), revealed loss of EID50 titre per dose value by log101.2, and log10 0.8 among two of the certified vaccine batches; with one of the certified vaccines retaining its original EID50 titre per dose value. This result attest that NDVI-2 thermostable vaccine produced at NVRI, Vom Nigeria are robust and of high quality. Thus, the findings of this study have further demonstrated that temperature variations, prolonged vaccine transportation under poor cold chain can affect the EID50 per dose value of a wholesome, field fit vaccine irrespective of the vaccine thermostability.
Proposed Strategy for Pharmaceutical Industry (Case Study: PT Bio Farma Persero)
Authors: Prayogi Reynaldy , Wandebori Harimukti 
Published: October 2020

PT Bio Farma (Persero) is a state-owned company that runs its business in the pharmaceutical industry, namely Vaccines and Anti-Sera products, so it has an important role to play in improving the quality of life in Indonesia. In addition, Bio Farma already has the capability to export its products because it already has WHO pre-qualifications.
PT Bio Farma (Persero) in distributing its products has two market sectors, namely the domestic and international sectors. In running its business, the company has several busines issue, namely Halal Product Regulation, High Rate of Raw Materials, Declining of Export Sales, Polio Eradication, and Global Covid Outbreak.
To analyze the internal condition, it used PESTEL analysis, Porter Five Forces and Competitor Analysis. To analyze the external condition, it used Resource Analysis and Value Chain Analysis are used. From all of these analyzes, a SWOT Analysis will be obtained to formulate the right strategy, and to propose Corporate, Business, and Functional Strategies that can be carried out by the company.
The right corporate strategy is the Diversification Strategy, this strategy aims to develop the company's products and markets to increase its competitiveness. Meanwhile, the right Business Strategy is Integrated Cost Leadership/Differentiation, this strategy aims to provide unique value to the company's products and create value chain efficiency.
Acceptance Model of Hospital Information Management System: Case of Study in Indonesia
Authors: Gomer Suko , Hasyim . , Kusumapradja Rokiah 
Published: October 2020

In this digital era, Hospitals must follow the competition that demands professionally managed services which cannot be separated from the role of computer technology. Therefore, a hospital needs a management information system that can integrate all its activities in order to improve performance and services, which is better known as Hospital Information System Management (HIS). The purpose of this study is to analyze the actual application of hospital management information systems using the Technology Acceptance Model (TAM) method with behavior intention as the intervening variable.
This research method is done using the quantitative approach, type of causality in the form of survey, one short study time horizon in the form of a questionnaire using Path Analysis. The analysis units are 100 respondents of employees at Metropolitan Medical Centre Hospital in Jakarta, who used HIS 2020. Purposive Sampling was used as the sampling technique. The results showed that attitude towards using HIS had a positive effect on behavioral intention to use. Perceived Usefulness has a positive effect on behavioral intention to use. Perceived Ease of use has a positive effect on behavioral intention to use. Behavioral intention to use has a positive effect on actual technology to use. Attitude toward using has a positive effect on actual technology to use. Perceived Ease of use has a positive effect on actual technology to use. The research findings indicate that the behavioral intention to use variable is a variable that increases the use of HIS because it can benefit from the use by the user. The implication in realizing the increase in HIS requires policies and commitment of hospital management in mandatory, advocacy, socialization, training, monitoring and evaluation related to HIS in each unit.
Evaluation of Risk Parity Asset Allocation Strategy in Indonesia Mutual Fund During 2010–2019 Period
Authors: Kurniawan Wayan Mahendra , Sumirat Erman 
Published: October 2020

Indonesia as the largest country in Southeast Asia have the highest GDP among the other countries in the region. In 2011, McKinsey & Company conducted a research to understand the annual consumer spending trend in Indonesia. According to the research, financial services will be the main consumption in Indonesia in 2030. Despite those promising situations, mutual fund industry in Indonesia was facing a big challenge in 2019. During 2019, Indonesia Financial Authority (OJK) has suspended 37 mismanaged mutual fund products from several investment managers. And actively managed mutual funds will have more exposure on this mismanagement risk.
Aside from mismanagement and underperforming risk of actively managed mutual fund, investor also facing high risk of equity asset class. Recently, IDX Composite (IHSG) experience a tremendous -28% drop in Q1 2020. Biggest peak to bottom drawdown during that period was -37,49% from 14 January 2020 until 24 March 2020. This situation creates a challenge for mutual fund sales agent (APERD).
But a challenging situation also offers opportunities. Mutual fund sales agent (APERD) that can offer optimum asset allocation suggestion that can give maximum risk protection can take advantage of these situation. One such unique strategy that has not been applied by other mutual fund sales agent (APERD) is risk parity that became popular after 2008 financial crisis.
This research applied risk parity framework in passively managed mutual fund because most of actively managed mutual funds in Indonesia underperform the benchmark in the 10-year period. Because of that, passively managed mutual funds provide better investment opportunity. Four equity indexes (LQ45, Jakarta Islamic Index, Bisnis 27, and Sri Kehati) and one passively managed fixed income mutual fund (ABF Indonesia Bond Index Fund) that have existed for 10-year period was chosen to apply the risk parity method. Sharpe ratio calculation is used to evaluate the portfolio performance compared to commonly used portfolio strategy in the world according to 2018 Legg Mason Global Investment Survey.
Result of the analysis is that risk parity portfolio offer better Sharpe ratio compared to commonly used portfolio strategy in the world. Result of 2009 - April 2020 back-testing process also show that risk parity can protect investor from equity market downturn in 77.3% of the case. With above result, risk parity can offer better risk protection for Indonesia individual investor.
Political Connection, Institutional Ownership and Tax Aggressiveness in Indonesia
Authors: Anggraini Yety , Widarjo Wahyu 
Published: October 2020

This study aims to analyze the effect of political connection and institutional ownership toward tax aggressiveness on manufacturing companies listed on Indonesia Stock Exchange. Samples for this study are 62 manufacturing companies listed between the periods of 2014 - 2018, hence obtained 310 observations. Result of this study shows that political connection of the directors and institutional ownership have positive and significant effect toward tax aggressiveness, while the political connection of the board of commissioners does not significantly affect toward the tax aggressiveness. Furthermore, this study also finds the difference of political connection and institutional ownership between big companies and small companies. The effect of political connection of the directors is stronger in small companies than big companies, while the effect of political connection of the board of commissioners toward tax aggressiveness is stronger in big companies than small companies.
Literature Study of Problem Based Learning Model Against Students Mathematical Motivation (Based on Indonesian Language Book)
Authors: Zebua Try Gunawan 
Published: October 2020

This study aims to describe whether the Problem Based Learning Model can be used for students' motivation problems in learning mathematics, what kind of motivation is successfully provided by the Problem Based Learning Model, and how the Problem Based Learning Model can make students have motivation in learning mathematics. The research method used is the Literature Research Method, by conducting a literature review through books in Indonesian. To maintain the quality of the material being studied, Indonesian language books are often used as references and written by experts (for example professors) which are proven based on tracking activities carried out in various journals, books, and from the Higher Education Database (pddikti). Data analysis techniques were carried out in 3 stages, namely: organize, synthesize, and identify. The results showed that the Problem Based Learning Model can be used for students' motivation problems in learning mathematics, intrinsic motivation is the type of motivation provided by the Problem Based Learning Model and the Problem Based Learning Model can make students have motivation in learning Mathematics because it is directly associated with the real world, so students feel mathematics is very useful and motivation will emerge.
Developing Ethnomatematics-Based Flipbook in Circle Material at VIII Grade of Junior High School
Authors: S. A. M. M Maghfiroh , Suharman Agus , Ramadhona Rezky 
Published: October 2020

Every ethnic group has various shapes, sizes, and cultural patterns that are interesting to study. Incorporating cultural elements in learning mathematics as the representation of ethnomatematics is helpful to introduce cultural values to the younger generation implicitly. The combination of technology and ethnomatematics for creating learning media should be tried because it contain a positive values for attracting students' learning interest. This study purposes to develop ethnomatematics-based flipbook in circle material at VIII grade of junior high school. The results show that ethnomatemics-based flipbook is appropriate to apply. The validation result of material experts is 80%, validation of media experts is 77%, and and from the student questionnaire responses is 74%.
Redes de apoio social à família de pessoas com problemas decorrentes do uso de drogas: percepção de familiares cuidadores
Authors: Pires Ronaldo Rodrigues , Alencar Alexsandro Batista de , Carvalho Luana Vieira de , Rodrigues Francisco Diones Araujo , Lima Raquel Cerdeira de , Sampaio José Jackson Coelho 
Published: October 2020

Objetivo: Compreender quais são as redes de apoio social utilizadas por familiares cujos membros fazem uso problemático de drogas e como estes avaliam o apoio recebido. Métodos: Trata-se de estudo de natureza qualitativa conduzido com familiares que acompanhavam usuários de um Centro de Atenção Psicossocial álcool e outras drogas. Foram realizadas entrevistas e a análise das informações coletadas foi baseada na técnica da Análise de Conteúdo. Recebeu aprovação ética com o parecer CAAE: 45607515.9.0000.5534. Resultados: Os resultados indicaram que, por um lado, a própria família e instituições religiosas formam a principal rede de apoio social informal. Por outro, o Centro de Atenção Psicossocial álcool e outras drogas, Unidade de Pronto Atendimento e hospital psiquiátrico compõem a rede de apoio social formal. Estes últimos apresentam-se desarticulados e pouco acolhedores às demandas dos familiares. Considerações finais: As redes de apoio sociais dos sujeitos desta pesquisa são constituídas por um reduzido repertório de pessoas e lugares. Desse modo, impõe-se a reflexão sobre a urgência de integrar espaços do território como potenciais produtores de acolhimento e cuidado, envolvendo a pessoa que usa drogas, sua família e a comunidade.
Efficacy of mentoring skills in Indian Air Force suicide prevention training: Challenges and opportunities
Authors: Thomas B , Chaturvedula S 
Published: October 2020

Introduction:
Mental health promotion and suicide prevention are important initiatives of Indian Air Force (IAF) for its personnel. Institute of Aerospace Medicine (IAM), Bengaluru, has been conducting suicide prevention training programs for the IAF personnel since 1997. More than a 100 programs have been completed. In-time identification of the vulnerable, empowerment of instructors, provision of information about suicide prevention and improvement of approach toward the ab initio who are at risk are the focus of the suicide prevention program (SPP). This paper aims at assessing the efficacy of the mentoring skills imparted during the suicide prevention training in successfully identifying and providing support to the vulnerable ab initio cadets in the training establishments of IAF.

Material and Methods:
Mentors (n = 34) who are instructors in the training establishments in IAF and who have completed SPP conducted by IAM participated in the study. A feedback tool which was to assess the usefulness of the SPP in terms of the extended use of mentoring skills in their work, problems faced in the identification of the vulnerable persons, challenges faced in their mentoring activities were administered. Qualitative analysis was carried out and compiled.

Results:
Qualitative analysis brought out certain important issues regarding the challenges faced by the mentors and their competency in effectively dealing with the challenges. The results provide support in improving the existing SPPs and the role of mentors in mental health promotion in IAF.

Conclusion:
Suicide prevention program being conducted at IAM (IAF) was found to be beneficial to the mentors. It also addressed some of the professional and personal challenges faced by them. The findings of the study has brought out important take home messages for refining the program in the future.
Accident of a civil passenger aircraft at a military airfield: The Casevac experience
Authors: Sarkar R , Mohapatra SS 
Published: October 2020

Introduction:
There are many civil airports in India wherein the airfield and flying operations are controlled by the military whereas, the Airports Authority of India (AAI) controls the civil terminal. Accident of a civil aircraft on such a base poses unique challenges. This paper discusses the medical contingency plan of a Naval Air Station to deal with civil aircraft crashes based on a civil aircraft incident.

Case Details:
In the early morning of late Dec in 2016, a Mumbai bound civil flight (Boeing 737) took off from an Indian Navy controlled airfield. While initiating the take-off roll from RW, it veered off the runway towards right and came to halt along the perimeter road 230 m north of the runway edge, on hard rocky ground. There were 154 passengers and 7 crew members who were evacuated from the aircraft, through emergency chutes. Few passengers escaped through the over wing hatches. Twenty passengers sustained injuries, mostly involving the lower limbs. This was primarily due to jumping on hard rocky ground and falling and tripping on rocks while moving away from the aircraft. An analysis was done to understand the limitations on the existing medical contingency plan.

Discussion:
The ICAO Airport Services Manual Part 7 on Airport Emergency Planning (Doc 9137-AN/898 Part 7) is the guiding reference for all airports on Airport Disaster and Planning. The Medical Services portion delineates clearly the role of the Medical Aid Providers. In the instant case, the medical department had successfully handled the casualty evacuation and their medical management. SOP and the existing medical contingencies were effectively used. A post-accident analysis in the instant case revealed that 17 out of 25 checklist points were satisfied. The lessons learned from the incident have been discussed in the paper.
Percutaneous Bilateral Adrenal Radiofrequency Ablation in Severe Adrenocorticotropic Hormone-dependent Cushing Syndrome
Authors: Rosiak Grzegorz , Milczarek Krzysztof , Konecki Dariusz , Otto Maciej , Rowinski Olgierd , Zgliczynski Wojciech 
Published: October 2020

Objectives:
The objectives of the study were to evaluate adrenal radiofrequency ablation (RFA) as a method of treatment in patients with severe adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome, among whom bilateral adrenalectomy is not a suitable option.

Material and Methods:
Five patients with ACTH-dependent Cushing syndrome underwent RFA of both adrenal glands. Four of them presented with Cushing disease unsuccessfully treated with pituitary surgery and medical therapy, while one patient had ACTH-dependent Cushing syndrome due to pancreatic endocrine tumor with liver metastases. All patients were disqualified from adrenalectomy due to morbid obesity or lack of consent.

Results:
A technical success was obtained in all cases, with only one re-intervention necessitated by a cooling effect of the inferior vena cava. Despite pre-procedural adrenergic blockade, severe hypertension was noted during the procedure in three cases, this being treated immediately using direct-acting vasodilators. No complications occurred otherwise. In all cases, significant improvement of clinical symptoms was observed, as well as marked decreases in levels of serum cortisol, free urine cortisol, and dehydroepiandrosterone sulfate.

Conclusion:
Bilateral RFA under CT-guidance is technically feasible and clinical improvement can be achieved using the method. In patients disqualified from adrenal surgery, RFA might be considered as an alternative method of ACTH-dependent Cushing syndrome treatment.
Foot Massage Menurunkan Nyeri Post Operasi Sectio Caesarea Pada Post Partum
Authors: Sari Dewi Nurlaela , Rumhaeni Aay 
Published: October 2020

ABSTRAK
Sectio caesarea merupakan tindakan alternatif dalam proses persalinan untuk menyelamatkan ibu dan janin. Ibu Bersalin dengan operasi sectio caesarea dilakukan pembedahan pada dinding abdomen dan dinding rahim. Dampak yang paling sering muncul dirasakan oleh postpartum dengan post operasi sectio caesarea adalah nyeri. Nyeri akan berdampak pada bounding attachment terganggu, mobilisasi terbatas, Activity Daily Living (ADL) terganggu serta berpengaruh terhadap Inisiasi Menyusui Dini (IMD). Asuhan yang diberikan terbatas pada terapi farmakologi dibandingkan non farmakologi. Foot massage adalah salah satu terapi non farmakologi yang dapat membantu menutup gerbang di posterior horns dari sumsum tulang belakang dan memblokir bagian dari nyeri ke sistem saraf pusat. Tujuan penelitian ini untuk mengetahui pengaruh foot massage terhadap skala nyeri pada klien post operasi sectio caesarea di RS AMC. Penelitian ini merupakan penelitian pre eksperimen dengan pendekatan one group pre test post test design. Jumlah sampel yang digunakan berjumlah 27 orang dengan menggunakan teknik purposive sampling. Instrumen yang digunakan adalah Numeric Rating Scale (NRS) dan prosedur kerja foot massage. Responden dilakukan foot massage selama 20 menit selama 2 hari. Data di analisis dengan menggunakan uji wilcoxon. Hasil penelitian menunjukkan lebih dari setengah klien post operasi sectio caesarea berada di skala nyeri 6 sebelum dilakukan foot massage dan hampir setengah memiliki skala nyeri 3 sesudah dilakukan foot massage dan didapatkan nilai p value = 0.000, sehingga disimpulkan ada pengaruh foot massage terhadap skala nyeri pada klien post operasi sectio caesarea. Diharapkan rumah sakit dapat menjadikan foot massage sebagai salah satu alternatif manajemen non farmakologi dalam penanganan nyeri.

Kata kunci: Foot Massage; Post Partum; Nyeri; Sectio Caesarea
Dampak Tempat Pembuangan Akhir Sampah (TPA) Terhadap Gangguan Kesehatan Masyarakat
Authors: Axmalia Astry , Mulasari Surahma Asti 
Published: October 2020

Kehadiran suatu tempat pembuangan akhir sampah (TPA) dalam suatu wilayah tentu akan menimbulkan masalah bagi penduduk sekitar, terutama yang menetap dengan jarak < 1 km. berdasarkan peraturan pemerintah No 18 tahun 2012 bahwa jarak pemukiman harus lebih dari 1 km. apabila tempat pembuangan akhir sampah tidak dikelola dengan baik, tentu akan menyebabkan pencemaran kualitas air, pencemaran udara, pencemaran tanah dari tumpukan sampah yang ditimbun. Studi literatur ini bertujuan untuk mengetahui dampak kesehatan pada masyarakat yang tinggal disekitar tempat pembuangan akhir (TPA) sampah dan faktor resiko yang dapat meningkatkan gangguan kesehata masyarakat. Metode yang digunakan dalam kajian ini adalah literature review. Pengumpulan literatur dilakukan melalui database http://garuda.ristekdikti.go.id dan Google Scholar yang diterbitkan dalam kurun waktu tahun 2015 sampai dengan 2019. Ditemukan keluhan gangguan Kesehatan pada masyarakat sekitar TPA yaitu penyakit kulit, diare, gangguan pernapasan, nyeri dada, mata pedih, tenggorokan kering, tenggorokan panas, kepala pusing, batuk-batuk, cacingan dan sesak napas. Terdapat faktor yang juga menyebabkan gangguan Kesehatan masyarakat disekitar TPA adalah faktor lingkungan seperti buruknya kualitas udara yang dipengaruhi oleh pencemaran air, pencemaran udara, pencemaran tanah yang dapat menyebabkan penyakit muncul akibat adanya penumpukan dan penimbunan sampah yang menyebabkan perkembangbiakan bakteri, vector penyakit dan virus.

Kata Kunci: TPA Sampah , Gangguan Kesehatan
DEMAM TIFOID: MANIFESTASI KLINIS, PILIHAN TERAPI DAN PANDANGAN DALAM ISLAM
Authors: Levani Yelvi , Prastya Aldo Dwi 
Published: October 2020

Typhoid fever is an acute infectious disease of the digestive system caused by the bacteria Salmonella typhi or Salmonella paratyphi. Typhoid fever is a global infectious disease in which an estimated 26.9 million cases of typhoid fever are found worldwide. Typhoid fever is especially common in developing countries because it is associated with poor sanitation. Clinical manifestations of typhoid fever that arise can vary from mild to severe symptoms. Symptoms of typhoid fever that are often found are fever, malaise, abdominal pain and constipation. Culture examination is a gold standard examination in establishing the diagnosis of typhoid fever. But this examination is rarely done. The first-line treatment option for typhoid fever is chloramphenicol. However, as the bacterial resistance to chloramphenicol increases, the main therapeutic choice for typhoid fever is the fluoroquinolone antibiotic.