bluuebunny/crossref_metadata_2025_split huggingface dataset:
Syndrome of early vascular aging in persons working under the influence of industrial aerosol
Authors: Milyutina M. Y. , Makarova E. V. , Ivanova Ju. V. , Men’kov N. V. , Plastinina S. S. 
Published: November 2019

Introduction.Currently, the concept of early vascular aging, manifested by an increase in the stiffness of the vascular wall, is gaining popularity. As a method of diagnosis of this syndrome, volumetric sphygmography is increasingly used to determine the cardiovascular ankle vascular index and estimated age. In addition to studying the impact of traditional cardiovascular risk factors on the development of vascular rigidity, a promising direction is the search for additional factors that reduce the elasticity of the vascular wall.The aim of the studywas to assess the effect of industrial aerosol on the development of early vascular aging syndrome in metallurgical workers.Materials and methods. 155 men working at the metallurgical enterprise were examined. The main group included 95 people working in conditions of exposure to industrial aerosol. The comparison group included 60 workers not exposed to industrial aerosol. All subjects underwent periodic medical examination, assessment of blood lipid spectrum, smoking status and experience, study of elastic properties of the vascular wall by volumetric sphygmography.Results.The study showed that in persons working under the influence of industrial aerosol, the cardiovascular ankle vascular index was significantly higher than in the comparison group (7.13 [6.3; 8] and 6.75 [6.1;7.13], respectively, p=0.006). The estimated age remained comparable with the chronological age of the two groups, but was significantly higher in the main group (42 [29;49] years and 37.1 [29;44] years, respectively, p=0.014). An increase in the cardiovascular-ankle vascular index relative to the age norm was revealed in 33.6% of the surveyed main group, which is twice higher than this indicator of the comparison group (16.6%). According to the calculated vascular age, early vascular aging was detected in 28.4% of the main group and in 13.3% of the comparison group. Signifi cantdiff erences appear when working in hazardous conditions for more than 10 years in the age category from 35 to 45 years.Conclusions.The obtained results indicate a high prevalence of early vascular aging in persons working under the influence of industrial aerosol.
The effect of intense physical exertion on the biochemical parameters of antioxidant protection systems and nitric oxide in swimming athletes
Authors: Blinova T. V. , Strakhova L. A. , Kolesov S. A. 
Published: November 2019

Introduction. Intense physical activity leads to a violation of homeostasis, which is supported by a balanced work of the body’s defense systems against oxidative stress, in particular, antioxidant, thiol disulfide and nitric oxide system. The study of these indicators will improve the mechanisms of adaptation of the human body to physical activity.The aim of the study was to identify the features of changes in antioxidant protection systems and nitric oxide during intense physical activity in athletes-swimmers.Materials and methods. Blood of athletes-swimmers (n=30, age 23,0±2,5 years) in the conditions of intensive physical loadings is investigated. Oxidative stress, total serum antioxidant capacity, glutathione levels and nitric oxide metabolites were studied by photometric biochemical methods.Results. In 73.3% of athletes after intense physical activity remained elevated levels of oxidized glutathione, 30% had a high level of oxidative stress, 26.7% of the level of antioxidant capacity of serum is low, 73.3% was reduced relative to the initial level of the concentration of nitric oxide metabolites.Conclusion. Intense physical activity leads to oxidative stress and disturbances in the antioxidant system of the athlete’s body. With increasing load, the degree of violations increases. The level of oxidative stress increases, the total antioxidant capacity of serum decreases, the functioning of glutathione is disrupted. Integral indicators of oxidative stress, as well as glutathione fractions can be recommended for monitoring the state of oxidative stress.
Health-saving technologies as prevention of occupational risk of emotional burnout in mental workers
Authors: Vasilyeva T. N. , Fedotova I. V. , Lebedeva M. A. , Chervyachkova O. A. 
Published: November 2019

In many countries, burnout due to stress at work is recognized as a professionally related disease. Of great importance for its prevention is the introduction of health-saving technologies.The aim of the research was to assess the state of their psycho-emotional sphere, the adequacy of the methodological complex used for psychodiagnostics, and the effectiveness of short-term psychological assistance projects by means of socialadapting and personal-developing technologies on the example of 2 groups of typical representatives with intellectual type of professional activity.In the study, consisting of three stages, two groups of subjects took voluntary part: 13 methodologists of the University and 20 managers of a trading fi rm. The first stage of the study consisted in the initial psychodiagnostics of indicators of the emotional sphere and functional state of the subjects. Different versions of psychodiagnostic tools were developed for each group. The second stage consisted in development and approbation of projects of short-term psychological help to workers. At the third stage the analysis of indicators of emotional sphere at subjects before and after participation in projects is carried out. The results of the study were processed using the usual methods of variational statistics according to the program Statistica 12.0. Initial psychodiagnostics of the studied parameters of the subjects showed signs of professional burnout. In Methodists, this was manifested by a pronounced degree of chronic fatigue index, a decrease in efficiency, a moderate degree of mental and physical fatigue, maladaptation in stress. Managers are also diagnosed with a high risk of maladjustment in stress, low values of indicators of functional state. In the course of participation in psychopath projects, the subjects of both groups showed positive dynamics of indicators of the emotional sphere.The obtained data allow to recommend these projects of health saving programs for practical use. The tested complex of psychodiagnostic tests allows to reveal signs of professional burnout and to estimate efficiency of programs of psychopathology. For the prevention of burnout syndrome and the formation of stress resistance, it is advisable to create a culture of health conservation at each workplace.
Synthesis and characterization of layered perovskite cathode materials for SOFC application
Authors: Harshitha Gandham , Pratihar Swadesh Kumar , Sahoo Abanti 
Published: November 2019

AbstractThe present study emphasizes the effect on the properties of cathode material by doping Ln = Nd, Pr on A-site cation in double-layered perovskite (AA′B2O5+δ). New cathode compositions Pr1-xNdxBa0.5Sr0.5Co0.5Fe1.5O5+δ (where x = 0, 0.25, 0.5, 0.75 and 1.0) were synthesized by the glycine-nitrate method and their calcination temperature was optimized. Refinement of X-ray diffraction patterns was performed to determine crystallographic information of the obtained phase. These synthesized powders were pelletized, then sintered at 1200–1250°C for microscopic analysis and electrical conductivity measurements. The chemical stability of these compositions with electrolyte gadolinium-doped ceria was also investigated. Pr1-xNdxBa0.5Sr0.5Co0.5 · Fe1.5O5+δ at x = 0 has shown highest conductivity of 315 S cm−1 at 550°C followed by x = 1.0 of 230 S cm−1 at 570°C. The findings of the present study reveal that these compositions may be used as cathode materials in solid oxide fuel cells.
Deposition temperature dependence on the bonding structure and mechanical properties of laser ablated boron-carbonitride thin films
Authors: Chen Zhuo , Liu Haixia , Wang Chuanbin 
Published: November 2019

AbstractBoron-carbonitride thin films were synthesized on Si (100) substrates by laser ablation, and the effect of deposition temperatures on the bonding structure and mechanical properties were studied to enhance the mechanical properties. The results of Fourier-transform infrared spectroscopy and X-ray photoelectron spectroscopy demonstrated that B–N, B–C, N–C and N=C bonds coexisted in the thin films with the ternary B–C–N hybridization structure. The deposition rate decreased as deposition temperatures increased, and the hardness and modulus fluctuated between 14.5 and 27.2 GPa and 146 and 246 GPa, respectively. The law of evaluation of the mechanical properties with deposition temperatures was found to be related to the changes in the bonding structure, and the maximum hardness and modulus were 27.2 GPa and 246 GP, respectively, when deposition temperature reached 400°C.
Signs of palmar dermatoglyphics as markers of atopic diseases
Authors: Shkolnikov V.S. , Klimas L.А. , Smolko D.G. , Makarchuk I.M. , Koliadenko S.V. 
Published: November 2019

The family character of atopic conditions, confirmed by many studies, has become the basis for the use of the method of dermatoglyphics to clarify the genetic nature of the “atopic march”. The purpose of the study was to identify differences in the features of palmar dermatoglyphics between patients with atopic dermatitis, allergic rhinitis and bronchial asthma. Primary indexes of palmar dermatoglyphics of young men and young women patients with atopic dermatitis, allergic rhinitis and bronchial asthma were taken from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya. According to the method of Cummins H. and Midlo Ch. dermatoglyphic study of 320 young men and young women with allergic rhinitis (n = 69), bronchial asthma (n = 108) and atopic dermatitis (n = 143) was performed. Quantitative indices of palmar dermatoglyphics were subject to analysis. The results obtained were processed using the Statistica 6.1 license package using non-parametric methods. It is established that the differences of quantitative indices of palmar dermatoglyphics between young men / young women with atopic dermatitis and allergic rhinitis cover 50.0% / 66.67%; among patients with atopic dermatitis and bronchial asthma – 38.89% / 33.33%; among patients with allergic rhinitis and bronchial asthma – 22.22% / 55.56% respectively. Thus, in young men, the marker potential for signs of palmar dermatoglyphics in the prognosis for the development of bronchial asthma in the presence of allergic rhinitis (22.22%) or atopic dermatitis (38.89%) are insignificant compared with the prognosis for the development of allergic rhinitis in the presence of atopic dermatitis (50.0%). In young women, the marker features of palmar dermatoglyphics in the prognosis for the development of bronchial asthma in the presence of atopic dermatitis are insignificant (33.33%) compared with the prognosis for the development of bronchial asthma in the presence of allergic rhinitis (55.56%) and the prognosis for the development of allergic rhinitis (66.67%).
Prospective evaluation of 4-D contrast-enhanced-ultrasound (CEUS) imaging in bladder tumors
Authors: Jokisch F. , Buchner A. , Schulz G.B. , Grimm T. , Weinhold P. , Pfitzinger P.L. , Chaloupka M. , Stief C.G. , Schlenker B. , Clevert D.-A. 
Published: November 2019

PURPOSE: The evaluation of the potential clinical benefit of four-dimensional ultrasound (4D-US) in the assessment of bladder cancer (BC). MATERIAL AND METHODS: 20 patients with indication for cystoscopy for suspicion of bladder cancer were prospectively included in this study. All patients underwent two-dimensional ultrasound (2D-US), contrast enhanced ultrasound (CEUS) and real-time four-dimensional ultrasound (4D-US). All acquisitions were compared to each other in regard to image quality. This assessment was done using a 6 point scale (1 = best). All patients underwent subsequently cystoscopy with resection of the tumor (TURB), due a histopathological analysis was possible. RESULTS: All examinations were performed successfully and no patient had to be excluded from the study. Patients acceptance of 4D-US was consistently good. No adverse events occurred. Image quality of real time 4D-US (score: 1.27±0.46) was significantly superior ( p < 0.001) to both, conventional 2D-US (score: 2.33±0.62) and also to 2D-CEUS (score: 2.00±0.53). In terms of tumor detection no superiority was evident for 4D-US compared to 2D-US or in utilization of CEUS (sensitivity = 0.89; specificity = 1.00; positive predictive value = 1.00; negative predictive value = 0.50; AUC = 0.944; (95% CI: 07.43–0.998)). CONCLUSION: The assessment of bladder cancer using real time 4D-US is feasible and improves the image quality and therefore also the precise anatomical consistency of intravesical tumor masses.
Intra-individual comparison of human nasal chondrocytes and debrided knee chondrocytes: Relevance for engineering autologous cartilage grafts
Authors: Lehoczky Gyözö , Wolf Francine , Mumme Marcus , Gehmert Sebastian , Miot Sylvie , Haug Martin , Jakob Marcel , Martin Ivan , Barbero Andrea 
Published: November 2019

OBJECTIVE: Implantation of autologous chondrocytes for cartilage repair requires harvesting of undamaged cartilage, implying an additional joint arthroscopy surgery and further damage to the articular surface. As alternative possible cell sources, in this study we assessed the proliferation and chondrogenic capacity of debrided Knee Chondrocytes (dKC) and Nasal Chondrocytes (NC) collected from the same patients. METHODS: Matched NC and dKC pairs from 13 patients enrolled in two clinical studies (NCT01605201 and NCT026739059) were expanded in monolayer and then chondro-differentiated in 3D collagenous scaffolds in medium with or without Transforming Growth Factor beta 1 (TGF β1). Cell proliferation and amount of cartilage matrix production by these two cell types were assessed. RESULTS: dKC exhibited an inferior proliferation rate than NC, and a lower capacity to chondro-differentiate. Resulting dKC-grafts contained lower amounts of cartilage specific matrix components glycosaminoglycans and type II collagen. The cartilage forming capacity of dKC did not significantly correlate with specific clinical parameters and was only partially improved by medium supplemention with TGF β1. CONCLUSIONS: dKC exhibit a reproducibly poor capacity to engineer cartilage grafts. Our in vitro data suggest that NC would be a better suitable cell source for the generation of autologous cartilage grafts.
Asymmetry inter-limb and performance in amateur athletes involved in high intensity functional training
Authors: Teixeira Rômulo Vasconcelos , de Queiros Victor Sabino , Dantas Matheus Peixoto , Assis Marina Gonçalves , Dantas Paulo Moreira Silva , de Araújo Tinôco Cabral Breno Guilherme 
Published: November 2019

BACKGROUND: The introduction of high-intensity functional training (HIFT) in sport gave rise to the exploration of determinants of success in sport. OBJECTIVE: To analyze whether asymmetry inter-limb is related to reduction in physical performance in amateur HIFT athletes. METHODS: Twenty-four HIFT amateur athletes, 11 women and 13 men, participated in the study. All volunteers performed three different jump tests: the squat jump (SJ), the countermovement jump (CMJ), performed unilaterally and bilaterally, and the 20-m sprint test. RESULTS: An overall asymmetry inter-limb of 9.5% in women and 9.3% men was not associated with any of the outcome measures. There were no significant differences in both genders between asymmetry, sprint, lower limbs’ muscle power (LLMP), SJ, CMJ and stretch-shortening cycle (SSC) ([Formula: see text] 0.05). CONCLUSIONS: Asymmetry inter-limb in CMJ does not seem to affect the performance of amateur athletes of HIFT. Thus, when the target is to maximise the performance, in the training programme, coaches should prioritise tasks that increase vertical jump capacity at the detriment of the unilateral jump.
Factors Associated with Supportive Care Service Use Among California Alzheimer’s Disease Patients and Their Caregivers
Authors: Newkirk Lori A. , Dao Virginia L. , Jordan Joshua T. , Alving Loren I. , Davies Helen D. , Hewett Linda , Beaudreau Sherry A. , Schneider Logan D. , Gould Christine E. , Chick Christina F. , Hirst Rayna B. , Rose Sophia Miryam Schüssler-Fiorenza , Anker Lauren A. , Tinklenberg Jared R. , O’Hara Ruth 
Published: November 2019

Background: Existing literature on factors associated with supportive care service (SCS) use is limited. A better understanding of these factors could help tailor SCS to the needs of frequent users, as well as facilitate targeted outreach to populations that underutilize available services. Objective: To investigate the prevalence of SCS use and to identify factors associated with, and barriers to, service use. Methods: California Alzheimer’s Disease Center patients with AD ( n = 220) participated in the study from 2006-2009. Patients and their caregivers completed assessments to determine SCS use. Cognitive, functional, and behavioral status of the patients were also assessed. A two-part hurdle analysis identified 1) factors associated with any service use and 2) service use frequency among users. Results: Forty percent of participants reported using at least one SCS. Patients with more impaired cognition and activities of daily living and more of the following: total number of medications, comorbid medical conditions, and years of education were more likely to use any SCS ( p < 0.05). Factors associated with more frequent SCS use included younger age, more years of education, older age of AD onset, female gender, and having a spouse or relative for a caregiver ( p < 0.05). Caregivers frequently indicated insufficient time as a reason for not receiving enough services. Conclusion: Factors associated with any SCS use mostly differed from those associated with SCS frequency, suggesting different characteristics between those who initiate versus those who continue SCS use. Our findings highlight the importance of targeted education on services and identifying barriers to long-term SCS use.
Effects of a Modified Tai Chi Program on Older People with Mild Dementia: A Randomized Controlled Trial
Authors: Huang Nayan , Li Wenjie , Rong Xiangjiang , Champ Mei , Wei Lian , Li Mo , Mu Haiyan , Hu Yueqing , Ma Zongjuan , Lyu Jihui 
Published: November 2019

Background: Tai Chi exercise is a non-pharmacological therapy that has received increased attention in recent years. A Tai Chi program has been specifically modified for older people with cognitive impairments by the research team. Objective: We aim to assess the effects of this Tai Chi program on mild dementia. Methods: Eighty older people with mild dementia were recruited and randomly assigned to a Tai Chi group or a control group. The Tai Chi group practiced the Tai Chi program three times a week for 10 months, while the control group continued receiving routine treatments. All participants were assessed for cognitive function, behavior/mood, and activities of daily living at baseline, 5 months, and 10 months. Results: The Tai Chi group performed better than the control group. Repeated measures ANOVA revealed a significant group×time interaction in the Montreal Cognitive Assessment (MoCA). Further analysis of sub-items of the MoCA showed a significant time effect in naming and abstraction. It was statistically significant in both main effect of time and group×time interaction in the Neuropsychiatric Inventory (NPI) and Geriatric Depression Scale (GDS). Paired sample t test showed the Tai Chi group scored lower at 5 and 10 months in the NPI and at 10 months in the GDS compared with baseline. The Tai Chi group scored lower than the control group at 10 months in the NPI and GDS. Conclusion: The results suggest this Tai Chi program may help improve cognitive function and mental well-being for older adults with mild dementia.
Correlation of functional echocardiography and clinical parameters in term neonates with shock
Authors: Bandyopadhyay T. , Saili A. , Yadav D.K. , Kumar A. 
Published: November 2019

BACKGROUND: To evaluate the correlation between functional echocardiography and clinical parameters in term neonates with shock. METHOD: Cross sectional study of 30 full term newborns who were clinically detected to have shock compared to 30 full term hemodynamically stable neonates. For statistical analysis, cases were further sub classified into cardiogenic and septic shock. RESULT: Functional echocardiography revealed inferior vena cava collapsibility index (cIVC), fractional shortening (FS), ejection fraction (EF), cardiac output and superior vena cava (SVC) flow were significantly lower whereas myocardial performance index (MPI) was significantly higher in babies with cardiogenic and septic shock as compared to the controls. Left ventricular end diastolic area (LVEDA) was significantly higher in cardiogenic shock whereas it was significantly lower in septic shock as compared to the controls. Also, cIVC was significantly lower and LVEDA was significantly higher in cardiogenic as compared to the septic shock. In cardiogenic shock SVC flow correlated significantly with capillary filling time and systolic blood pressure. The correlation between functional echocardiographic parameters of cardiogenic and septic shock showed that EF, FS and MPI were positively and significantly correlated (r 0.742, p 0.022 for EF, r 0.766, p 0.016 for FS and r 0.478, p 0.05 for MPI) whereas SVC flow and cIVC were negatively and significantly correlated between cardiogenic and septic shock (r – 0.655, p 0.045 for SVC flow and – 0.578, p 0.05 for cIVC). CONCLUSION: In the complex environment of neonatal intensive care unit detection of shock continues to be a major challenge. Functional echocardiography provides an adjunct information to the clinical assessment of shock and helps in monitoring the response to treatment.
Ultrasound guided central line insertion in neonates: Pain score results from a prospective study
Authors: Sabouneh Rami , Akiki Pierre , Al Bizri Ayah , El Helou Sally , Zeidan Smart , Al Hamod Dany 
Published: November 2019

BACKGROUND: Central lines can be placed through different techniques, either peripherally or centrally. Although they have the same aim, decision to use one of these modalities depends on the patient outcomes. The aim is to compare pain scores between ultrasound-guided central line insertion and peripherally inserted catheter in neonates in a prospective randomized single center study. METHODS: A randomized controlled trial was conducted in neonates requiring central venous access for any of the following reasons: total parenteral nutrition (TPN), antibiotics treatment for at least 7 days and having poor or difficult venous access. The study compared pain difference, in neonates, that were randomized between peripherally and ultra-sound guided centrally placed central lines using the validated pain score N – PASS. RESULTS: 61 neonates were enrolled in the study. US-guided CICC was associated with less pain as reported by the statistically significant lower pain score difference ( p-value <0.001) than the standard PICC. Additionally, the US-guided CICC had a higher rate of successful first attempt ( p = 0.012), lower overall number of attempts ( p < 0.001), and shorter procedure duration ( p < 0.001) as compared to standard PICC. CONCLUSION: US-guided CICC is a less painful technique than PICC line insertion associated with higher rate of successful first attempt, lower overall number of attempts and shorter procedure duration.