bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of the Wisconsin Upper Respiratory Symptom Survey-24, Chinese version
Authors: Wang Yuanyuan , He Zehui , Chen Simin , Liu Yuntao , Li Fang , Barrett Bruce , Lundborg Cecilia Stålsby , Zhang Zhongde , Su Guobin 
Published: February 2020

Abstract
Background The Wisconsin Upper Respiratory Symptom Survey (WURSS) is a validated English questionnaire to evaluate the severity of upper respiratory tract infections (URTIs). We aimed to develop a Chinese version of WURSS-24 (WURSS-24-C) and evaluate its reliability, validity and minimal important difference (MID). Methods The WURSS-24 was translated into Mandarin Chinese using the forward-backward translation procedure. People with Jackson-defined common cold symptoms within 48 hours of onset were recruited in Guangzhou, China, and followed for up to 14 days. The SF-8 (24 hours recall) assessing general mental and physical health was used as external comparator. Reliability, validity, and MID were evaluated. Results The WURSS-24-C was developed and found to be acceptable, relevant, and easy to complete in cognitive debriefing interviews. A total number of 300 participants (age 28.4±9.3, female 70%) were monitored for 2,500 person-days. Factor analysis: Exploratory factor analysis (EFA) suggested 4 domains, defined as activity and function, systemic symptoms, nasal symptoms, and throat symptoms. Confirmatory factor analysis (CFA) supported this 4-domain model with a Comparative Fit Index (CFI) of 0.93. Reliability assessment of the 4-domain-structure found Cronbach’s alphas of 0.943, 0.859, 0.882 and 0.849, respectively. Convergent validity indicator: The Pearson correlation coefficients between daily WURSS-24-C and the SF-8 were -0.780 and -0.721, for the SF-8 physical and mental health respectively. Estimates of MID for individual items varied from -0.41 to -1.14. Conclusion The WURSS-24-C is a reliable and valid questionnaire for assessing illness-specific quality-of-life health status in Chinese speaking patients with URTIs.
Research on comprehensive evaluation of Payment for ecological services effect of environmental pollution loss in Industrial Park
Authors: Han Xiuyan , Cao Tianyi 
Published: February 2020

Abstract
Background: China's industrial parks are the main force of economic development，payment for ecological services（PES）effect of environmental pollution loss in industrial parks is significant for sustainable development of industrial parks. In order to explore effective method of Payment for ecological services effect evaluation（ECEE）of the environmental pollution loss（EPL）in industrial parks, based on literature review and current situation analysis, 24 evaluation indicators of four kinds were selected to build the evaluation indicator system. According to requirements of Payment for ecological services effect evaluation of environmental pollution loss in industrial parks, niche suitability model (NFM) is introduced, based on analysis and improvement of which, spatial niche suitability model (SNSM) is constructed. Then, the application test of SNSM is carried out using related research data, taking Nanjing MV Industrial Park as an example. Results: The evaluation results show that the Payment for ecological services effect of environmental pollution loss in Nanjing MV industrial park shows an upward trend from 2011 to 2018, but the upward situation is imbalanced, and effect improvement of ecological environment compensation inputs and ecological environmental pollution is obviously lagging behind, and still the future work focus of Nanjing MV Industrial Park. Conclusions: Through comparative analysis, it is shown that the evaluation results of spatial niche suitability model are more in line with the actual situation of Nanjing MV Industrial Park, and this method is more suitable for the comprehensive evaluation of Payment for ecological services effect of environmental pollution loss. The research results of this paper provide an effective quantitative analysis method for Payment for ecological services effect management and prevention of Payment for ecological services risks of industrial parks.
Novel homozygous mutation in TUBB8 associated with oocyte maturation defect-2 in a consanguineous marriage family
Authors: Xing Qiong , Wang Ruyi , Chen Beili , Li Lin , Pan Hong , Li Tengyan , Ma Xu , Cao Yunxia , Wang Binbin 
Published: February 2020

Abstract
Purpose: To study the genetic basis of oocyte maturation defects, we performed clinical and genetic analysis of a pedigree. Variations in many genes may lead to the occurrence of oocyte maturation defects, but the specific functional mechanisms need to be further studied.Methods: One proband with oocyte maturation defect-2 receiving ovulation induction therapy and her parents were selected for clinical detection, whole exome sequencing and Sanger sequencing. One normal woman received ovulation induction therapy. Mutations were assessed after frequency screening of public exome databases. Then homozygous variants shared by the proband and her parents were selected.Results: Arrest of oocytes maturation was observed. A new missense mutation in TUBB8 (TUBB8: NM_177987: exon 2: c. C161T: p. A54V) was identified, which was shown to be novel compared with public databases. The variant was highly conserved among primates, and was suggested to be deleterious by online software prediction. Conclusions: The homozygote of this variant (TUBB8: NM_ 177987: exon 2:c.C161T: p.A54V) might affect spindle assembly, cause arrest of oocyte maturation and lead to oocyte maturation defect-2.
Preparation and characterization of PAN nanofibers containing boehmite nanoparticles for the removal of microbial contaminants and cadmium ions from water
Authors: Borhani Sedigheh , Asadi Arezo , Dabbagh Hossein A. 
Published: February 2020

Abstract
Nanofibers of polyacrylonitrile (PAN)/boehmite were prepared by electrospinning a homogeneous solution of PAN/DMF (dimethyl formamide). Enhancing the amount of boehmite nanoparticles (NPs) led to increase in the nanofibers' diameter. Samples had high pure water flux, which did not change significantly with boehmite concentration, but decreased with increasing electrospinning duration. Escherichia coli bacteria removal was remarkably more efficient, as it was enhanced from 72.33% to 97.37% with increase in the boehmite NPs' concentration from 0 to 10% wt. High bacterial removal efficiency could be attained by the large surface area of NPs, as well as the electrostatic force of attraction between NPs and microorganisms. The increase in boehmite concentration from 10 to 30 and 50% did not noticeably affect bacterial removal. Prolonging electrospinning time significantly enhanced bacteria removal. Hence, it was shown that 6-hour electrospinning of PAN/boehmite nanofiber layers composed of 50% boehmite led to 99.7%, 99.39%, 99.8%, and 74% E. coli, Staphylococcus aureus bacteria removal, particles' separation efficiency of 2 μm and cadmium adsorptivity, respectively, which were better than those obtained by using pure PAN nanofibers. E. coli bacterial removal efficiency of the sample was increased to 99.99% by repeating filtering four times. Considering the results, this PAN/boehmite nanofibers' membrane has potential application to purification of drinking water.
Removal of brilliant green (BG) from aqueous solution by using low cost biomass Salix alba leaves (SAL): thermodynamic and kinetic studies
Authors: Fiaz Rashida , Hafeez Muhammad , Mahmood Rashid 
Published: February 2020

AbstractThe removal of brilliant green dye (BGD) from aqueous solution by using Salix alba leaves (SAL) was carried out via batch studies. The maximum removal efficiency was found to be 95.2% with initial dye concentration 50 mg/L at 0.15 g adsorbent dosage, pH = 6, and 298 K temperature, and the equilibrium was observed within 3½ hours. The adsorption capacity increased (2.21–15.89 mg/g) from 10 to 50 mg/L of dye concentration. Kinetic and isotherm studies were also carried out. The results showed that pseudo-second order model better describes the adsorption mechanism. The isotherm equilibrium data analysis was carried out by using Freundlich and Langmuir models and the sorption process was observed to conform with the Langmuir isotherm with linear correlation coefficient (R2 = 0.99). The thermodynamic properties ΔG°, ΔH°, and ΔS° delineated that BGD adsorption over SAL was feasible, spontaneous, and endothermic between 303 and 323 K temperature.
Choosing various likelihood functions on uncertainty assessment in groundwater simulation-optimization model
Authors: Norouzi Khatiri Khadije , Niksokhan Mohammad Hossein , Sarang Amin 
Published: February 2020

Abstract
The main goal in this research is study of impacts of various likelihood functions on DREAM(zs) (Differential Evolution Adaptive Metropolis) method results in simulation-optimization model of aquifer. In this study, DREAM(zs) algorithm has been developed to study aquifer simulation-optimization model uncertainties. DREAM(zs) is used to investigate uncertainty of parameters of the simulation-optimization model in Isfahan-Barkhar aquifer, Isfehan province, Iran. This study is carried out on an aquifer simulation model of MODFLOW that is coupled with MOPSO (multi-objective particle swarm optimization) optimization. Three likelihood functions, L1, L2, and L3, are considered as informal and the remaining (L4 and L5) are represented as formal categories. Likelihood function L1 is Nash–Sutcliffe efficiency and L2 is based on minimum mean square error. L3 uses estimation of model error variance and L4 focuses on the relationship between the traditional least squares fitting and the Bayesian inference. In likelihood function L5 the serial dependence of residual errors is calculated using a first-order autoregressive model of the residuals. Results suggested that the parameters sensitivity depend on the likelihood function selection, and sensitivity of all parameters is not similar in different likelihood functions. MOPSO algorithm outputs indicated that likelihood function No. 5 has a higher speed in reaching convergence and this function also showed that objective functions had a better performance compared to the other likelihood functions.
Effects of total suspended solids, particle size, and effluent temperature on the kinetics of peracetic acid decomposition in municipal wastewater
Authors: Amerian Tasnim , Farnood Ramin , Sarathy Siva , Santoro Domenico 
Published: February 2020

AbstractIn this study, the influence of total suspended solids (TSS) and particle size as well as effluent temperature on peracetic acid (PAA) decomposition kinetics in municipal wastewater was investigated. PAA decomposition was best described following second order kinetics in primary effluent (PE) and first order kinetics in secondary effluent (SE) samples. For synthetic samples prepared by varying TSS levels, PAA demand increased on average by about 0.042 mg/L in PE and 0.034 mg/L in SE for every 10 mg/L increase in TSS. Similarly, the PAA decay rate constant in these samples increased at a rate of 0.0014 L/mg.min and 0.00039 min−1, respectively, per 10 mg/L TSS. To examine the effect of particle size, synthetic samples with narrow size fractions (20–45, 45–75, and 75–90 μm) were prepared. It was found that samples with smaller particle size fractions had a greater PAA demand and decay rate constant. Effluent temperature also enhanced the PAA decomposition rate with the calculated activation energies for PE and SE samples being 29,980 J/mol and 34,860 J/mol, respectively.
Pengembangan multimedia interaktif topik prinsip Archimedes untuk mengoptimalkan student centered learning
Authors: Diyana Tsania Nur , Supriana Edi , Kusairi Sentot 
Published: February 2020

Tujuan dari penelitian pengembangan ini adalah untuk menghasilkan produk multimedia interaktif pada mata pelajaran Fisika topik prinsip Archimedes untuk siswa kelas XI. Penggunaan multimedia sangat membantu siswa dalam memaksimalkan belajar mandiri (student centered learning) serta membantu siswa untuk memahami konsep dengan lebih baik. Metode penelitian pengembangan yang digunakan adalah Research and Development (R&D) dengan model ADDIE. Kelayakan multimedia interaktif topik prinsip Archimedes berbasis power point diperoleh dari hasil uji empiris pada 3 mahasiswa dengan hasil rata-rata 5.08 kategori sangat baik. Berdasarkan hasil penelitian kelayakan media yang telah dilaksanakan maka diperoleh kesimpulan bahwa multimedia interaktif topik prinsip Archimedes layak digunakan sebagai alternatif pembelajaran di luar waktu sekolah oleh siswa. Selain itu, dapat menjadi bahan belajar mandiri (student centered learning) yang mampu meningkatkan pemahaman konsep siswaKata kunci: Multimedia interaktif, prinsip archimedes, student centered learning Developing interactive multimedia in Archimedes principles to optimize student centered learning AbstractThe purpose of this development research is to produce interactive multimedia products on Physics subjects on the topic of Archimedes principles for grade XI students. The use of multimedia is very helpful for students in improving independent learning (student-centered learning) and helps students to understand concepts better. The research development method used is Research and Development (R&D) with the ADDIE model. The feasibility of interactive multimedia on the topic of Archimedes principles based on power point was obtained from the results of empirical tests on 3 students with an average result of 5.08 very good categories. Based on the results of a feasibility study on media that has been done it could be concluded about interactive multimedia, the principle of Archimedes used as an alternative worthy of learning outside of school time by students. Also, it can be self-learning materials that can improve student understandingKeywords: Interactive multimedia, Archimedes principles, student centered learning
Accuracy of Optical Heart Rate Sensing Technology in Wearable Fitness Trackers for Young and Older Adults: Validation and Comparison Study
Authors: Chow Hsueh-Wen , Yang Chao-Ching 
Published: February 2020

Background
Wearable fitness trackers are devices that can record and enhance physical activity among users. Recently, photoplethysmography (PPG) devices that use optical heart rate sensors to detect heart rate in real time have become popular and help in monitoring and controlling exercise intensity. Although the benefits of using optical heart rate monitors have been highlighted through studies, the accuracy of the readouts these commercial devices generate has not been widely assessed for different age groups, especially for the East Asian population with Fitzpatrick skin type III or IV.

Objective
This study aimed to examine the accuracy of 2 wearable fitness trackers with PPG to monitor heart rate in real time during moderate exercise in young and older adults.

Methods
A total of 20 young adults and 20 older adults were recruited for this study. All participants were asked to undergo a series of sedentary and moderate physical activities using indoor aerobic exercise equipment. In this study, the Polar H7 chest-strapped heart rate monitor was used as the criterion measure in 2 fitness trackers, namely Xiaomi Mi Band 2 and Garmin Vivosmart HR+. The real-time, second-by-second heart rate data obtained from both devices were recorded using the broadcast heart rate mode. To critically analyze the results, multiple statistical parameters including the mean absolute percentage error (MAPE), Lin concordance correlation coefficient (CCC), intraclass correlation coefficient, the Pearson product moment correlation coefficient, and the Bland-Altman coefficient were determined to examine the performances of the devices.

Results
Both test devices exhibited acceptable overall accuracy as heart rate sensors based on several statistical tests. Notably, the MAPE values were below 10% (the designated threshold) in both devices (GarminYoung=3.77%; GarminSenior=4.73%; XiaomiYoung=7.69%; and XiaomiSenior=6.04%). The scores for reliability test of CCC for Garmin were 0.92 (Young) and 0.80 (Senior), whereas those for Xiaomi were 0.76 (Young) and 0.73 (Senior). However, the results obtained using the Bland-Altman analysis indicated that both test optical devices underestimated the average heart rate. More importantly, the study documented some unexpected outlier readings reported by these devices when used on certain participants.

Conclusions
The study reveals that commonly used optical heart rate sensors, such as the ones used herein, generally produce accurate heart rate readings irrespective of the age of the user. However, users should avoid relying entirely on these readings to indicate exercise intensities, as these devices have a tendency to produce erroneous, extreme readings, which might misinterpret the real-time exercise intensity. Future studies should therefore emphasize the occurrence rate of such errors, as this will likely benefit the development of improved models of heart rate sensors.
Benefits and Disadvantages of Electronic Patient-reported Outcome Measures: Systematic Review
Authors: Meirte Jill , Hellemans Nick , Anthonissen Mieke , Denteneer Lenie , Maertens Koen , Moortgat Peter , Van Daele Ulrike 
Published: February 2020

Background
Patient-reported outcome measures (PROMs) are important in clinical practice and research. The growth of electronic health technologies provides unprecedented opportunities to systematically collect information via PROMs.

Objective
The aim of this study was to provide an objective and comprehensive overview of the benefits, barriers, and disadvantages of the digital collection of qualitative electronic patient-reported outcome measures (ePROMs).

Methods
We performed a systematic review of articles retrieved from PubMED and Web of Science. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed during all stages. The search strategy yielded a total of 2333 records, from which 32 met the predefined inclusion and exclusion criteria. The relevant ePROM-related information was extracted from each study.

Results
Results were clustered as benefits and disadvantages. Reported benefits of ePROMs were greater patient preference and acceptability, lower costs, similar or faster completion time, higher data quality and response rates, and facilitated symptom management and patient-clinician communication. Tablets were the most used ePROM modality (14/32, 44%), and, as a platform, Web-based systems were used the most (26/32, 81%). Potential disadvantages of ePROMs include privacy protection, a possible large initial financial investment, and exclusion of certain populations or the “digital divide.”

Conclusions
In conclusion, ePROMs offer many advantages over paper-based collection of patient-reported outcomes. Overall, ePROMs are preferred over paper-based methods, improve data quality, result in similar or faster completion time, decrease costs, and facilitate clinical decision making and symptom management. Disadvantages regarding ePROMs have been outlined, and suggestions are provided to overcome the barriers. We provide a path forward for researchers and clinicians interested in implementing ePROMs.

Trial Registration
PROSPERO CRD42018094795; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=94795
Wuhan 2019 Novel Coronavirus Pneumonia: A Case Report of Serial Computed Tomographic Findings in a Female Patient (Preprint)
Authors: Wei Jiangping , Xu Huaxiang , Xiong Jingliang , Shen Qinglin , Fan Bing , Ye Chenglong , Dong Wentao , Hu Fangfang 
Published: February 2020

UNSTRUCTURED

Background: From December 2019, the 2019 Novel Coronavirus (2019-nCoV) Pneumonia broke out in Wuhan, China. In this study, we present the finding of serial computed tomography in a female patient with 2019-nCoV.
Case presentation: We report a 40-year-old female who presented with the symptoms of fever, chest tightness, and fatigue. She was further diagnosed with 2019-nCoV confirmed by rRT-PCR. In terms of her chest CT findings, patchy consolidation shadows, and ground-glass opacities (GGOs) rapidly progressed in both lungs, peripherally. After treatment, the	previous lesions were almost absorbed, leaving the fibrous lesions.
Conclusions: If there is a history of fever or contact with the epidemic area, combined with the above CT findings, it is necessary to detect the nucleic acid of new coronavirus in time.
Estudio de los parámetros de proyección térmica por plasma de blancos de TiO2 usados en magnetrón sputtering
Authors: Jaramillo-Raquejo Daniela , Palacio-Espinosa Claudia Constanza , Ageorges Hélène 
Published: February 2020

La síntesis de películas delgadas por pulverización catódica o sputtering requiere la utilización de blancos o targets, que actúan como los materiales a partir de los cuales se elaboran los recubrimientos. Este trabajo está enfocado en la implementación del proceso de proyección térmica por plasma atmosférico para la fabricación de blancos de TiO2, que posteriormente puedan emplearse en la deposición de recubrimientos de TiO2 por magnetrón sputtering. Se partió de tres polvos de TiO2 comerciales de la marca Oerlikon Metco, los cuales fueron proyectados mediante diferentes parámetros de proyección para evaluar su efecto en la microestructura (porcentaje de poros y grietas en sección transversal) de los blancos de TiO2 obtenidos. Los blancos fueron caracterizados por microscopía electrónica de barrido y procesamiento de imágenes y utilizados en algunas pruebas de deposición sputtering para estimar la tasa de deposición. Los resultados permitieron identificar las variables que tienen un efecto más significativo sobre la microestructura de los blancos. En orden decreciente a la magnitud del efecto, estas variables son: la relación de gases generadores de plasma, la distancia de proyección, el flujo del gas de arrastre, la corriente en el arco eléctrico y la distribución de tamaños de partícula de la materia prima. Los porcentajes de defectos microestructurales encontrados durante la ejecución de las pruebas variaron entre 0.41 ± 0.30 % y 6.80 ± 2.03 %, rango que demuestra la importancia que puede llegar a tener el control de los parámetros de proyección en la fabricación de blancos mediante esta técnica.
Cepstral Analysis and Hilbert-Huang Transform for Automatic Detection of Parkinson’s Disease
Authors: López-Pabón Felipe O. , Arias-Vergara Tomas , Orozco-Arroyave Juan R. 
Published: February 2020

Most patients with Parkinson’s Disease (PD) develop speech deficits, including reduced sonority, altered articulation, and abnormal prosody. This article presents a methodology to automatically classify patients with PD and Healthy Control (HC) subjects. In this study, the Hilbert-Huang Transform (HHT) and Mel-Frequency Cepstral Coefficients (MFCCs) were considered to model modulated phonations (changing the tone from low to high and vice versa) of the vowels /a/, /i/, and /u/. The HHT was used to extract the first two formants from audio signals with the aim of modeling the stability of the tongue while the speakers were producing modulated vowels. Kruskal-Wallis statistical tests were used to eliminate redundant and non-relevant features in order to improve classification accuracy. PD patients and HC subjects were automatically classified using a Radial Basis Support Vector Machine (RBF-SVM). The results show that the proposed approach allows an automatic discrimination between PD and HC subjects with accuracies of up to 75 % for women and 73 % for men.