bluuebunny/crossref_metadata_2025_split huggingface dataset:
Circadian Clocks in the Regulation of Neurotransmitter Systems
Authors: Kiehn Jana-Thabea , Faltraco Frank , Palm Denise , Thome Johannes , Oster Henrik 
Published: October 2019

AbstractTo anticipate and adapt to daily recurring events defined by the earth’s rotation such as light-dark and temperature cycles, most species have developed internal, so-called circadian clocks. These clocks are involved in the regulation of behaviors such as the sleep-wake cycle and the secretion of hormones and neurotransmitters. Disruptions of the circadian system affect cognitive functions and are associated with various diseases that are characterized by altered neurotransmitter signaling. In this review, we summarize the current knowledge about the interplay of the circadian clock and the regulation of psychiatric health and disease.
Clusters of investors around initial public offering
Authors: Baltakienė Margarita , Baltakys Kęstutis , Kanniainen Juho , Pedreschi Dino , Lillo Fabrizio 
Published: October 2019

AbstractThe complex networks approach has been gaining popularity in analysing investor behaviour and stock markets, but within this approach, initial public offerings (IPOs) have barely been explored. We fill this gap in the literature by analysing investor clusters in the first two years after the IPO filing in the Helsinki Stock Exchange by using a statistically validated network method to infer investor links based on the co-occurrences of investors’ trade timing for 69 IPO stocks. Our findings show that a rather large part of statistically similar network structures form in different securities and persist in time for mature and IPO companies. We also find evidence of institutional herding.
Harvesting synergy from sustainable development goal interactions
Authors: Pedercini Matteo , Arquitt Steve , Collste David , Herren Hans 
Published: October 2019

Significance
The sustainable development goals (SDGs) offer the global community a compelling vision and universally agreed-upon framework to achieve a sustainable and equitable future—but present a costly undertaking in the short term. Our research suggests that synergetic effects arising from appropriately designed policy mixes can bring significant cost savings and improve SDG attainment. Identifying and quantifying synergies requires innovative and unorthodox approaches to policy analysis such as those operationalized in our 3 pilots. The synergy assessment method and typology introduced in this paper are widely applicable, even though the patterns of synergies vary considerably between countries. Our pilot studies focus on national policy for the SDGs. Our approach is nevertheless generalizable to integrated planning at other scales and time horizons.
Quantum Monte Carlo with the Langevin Equation: Coupled Bose-Fermi Systems
Authors: George Batrouni G. , Scalettar Richard T. 
Published: October 2019

Abstract
We describe the algorithmic details and a performance evaluation of a Langevin approach to a strongly interacting electron-phonon system, and show it has a near linear scaling with lattice size N

s
. Many of the limitations of previous attempts to employ such methods to condensed matter lattice Hamiltonians are absent. In particular, the iterative linear algebra solution remains well behaved at strong coupling and low temperatures. The use of Fourier Acceleration is crucial for efficiency, and its use makes the method competitive with the widely-used local update methods, which scale as

N
s
3

for on-site interactions and

N
s
4

for long range electron-phonon coupling, even on rather small lattice sizes.
The Angular Fractal Dimension in Galaxy’s Distributions
Authors: Khalifa Loay , Pando Jesùs 
Published: October 2019

Abstract
The study of large scale structure (LSS) of the Universe has entered a precision era due to all-sky surveys and numerical simulations. The new data has provided a way to bring new methods to bear to analyze the cosmology as probed by large scale structure. We use wavelet packets to investigate fractal point-processes on galactic scales. In particular, we develop a method to calculate the angular fractal dimension of galaxy distributions as a function of cosmological comoving distance. Taking advantage of the self-similarity and localization properties of discrete wavelets, we compute the angular fractal dimension of galaxies in narrow redshift bins. The narrow bins assure that dynamical evolution in the range being studied has not occurred to a significant extent. We use both real and simulated data from the Baryon Oscillation Spectroscopic Survey (BOSS) and the Mock Galaxy Catalogs produced by the Sloan Digital Sky Survey (SDSS). Using the wavelet packet power spectrum, we find areas in the galaxy distribution which have power law like behavior indicating fractal processes are present. The exponent of the power law is the Hurst exponent H, which is directly related to the fractal dimension of spatial point processes. We find the fractal dimension ranges from D = 1.1 to D = 1.4 for BOSS Galaxies while it ranges from D = 1.4 to D = 1.8 for Mock Galaxy Catalogs. The results are mildly dependent on the number of galaxies present in each redshift bin and less so on the resolution at which the data is binned. We conclude that this method can be used to characterize large scale structure and its evolution as a function of redshift. There are hints that the galaxy distribution may be fractal at higher redshifts than previously reported, however more data is necessary before a firmer conclusion is reached.
Electronic properties of binary compounds with high fidelity and high throughput
Authors: Das Protik , Bazhirov Timur 
Published: October 2019

Abstract
We present example applications of an approach to high-throughput first-principles calculations of the electronic properties of materials implemented within the Exabyte.io platform[1, 2]. We deploy computational techniques based on the Density Functional Theory with both Generalized Gradient Approximation (GGA) and Hybrid Screened Exchange (HSE) in order to extract the electronic band gaps and band structures for a set of 775 binary compounds. We find that for HSE, the average relative error fits within 22%, whereas for GGA it is 49%. We find the average calculation time on an up-to-date server centrally available from a public cloud provider to fit within 1.2 and 36 hours for GGA and HSE, respectively. The results and the associated data, including the materials and simulation workflows, are standardized and made available online in an accessible, repeatable and extensible setting.
A Wannier orbital based method for resonant inelastic x-ray scattering simulation
Authors: Jia Chunjing 
Published: October 2019

Abstract
We report an algorithm for simulating oxygen K-edge RIXS for weakly correlated systems, using maximally localized Wannier functions as the basis set. The N-electron wavefunctions are formulated using single Slater determinants, and many-body effects are treated explicitly at the dipole matrix element level. The simulated results for oxygen K-edge RIXS from solid state Li2CO3 matches well with the experimental data. Aside from being efficient and reasonably accurate, this algorithm also shows potential to extend to more complex RIXS problems.
Driving force dependence of the height of a faceted macrostep in non-equilibrium steady-state crystal growth
Authors: Akutsu Noriko 
Published: October 2019

Abstract
In order to understand the dynamics of the self-organized macrosteps, the vicinal surface with faceted macrosteps is studied by the Monte Carlo method based on a microscopic lattice model, the restricted solid-on-solid model with point-contact-type step-step attraction (p-RSOS model). We focus on the dynamical effects caused by the change of the surface roughness or the change of the kink density which are masked by the effect of the surface and volume diffusion of the crystal atoms in the ambient phase. Contrast to the step-bunching in the diffusion-limited cases, the height of the faceted macrostep decreases as the driving force for the crystal growth increases.
Crambin Homologues in the H0P Lattice Model
Authors: Zhang Zewen , Farris Alfred C.K. , Shi Guangjie , Wüst Thomas , Landau David P. 
Published: October 2019

Abstract
To compare folding behavior among lattice proteins which have similar corresponding structures in nature, Crambin homologues are tested in the semi-flexible H0P lattice model using replica-exchange Wang-Landau sampling. Our simulation shows that, at low temperature, these lattice homologues have two common signals in their specific heat curves, implying similarity in the thermodynamic behaviors; while the structural behaviors are more diverse, showing the different stability of their ground state structures at very low temperature. The ground state structures of different homologues can also vary dramatically.
Quantum chemical analysis of reaction indices and reaction path for drug molecules
Authors: Otsuka Takao , Okimoto Noriaki , Saito Hiroaki , Taiji Makoto 
Published: October 2019

Abstract
We performed a quantum chemical study on evaluating chemical reactivity for drug molecules in Cytochrome P450 (CYP) metabolic reaction. In this study, we focused on two insights for analysing the chemical reactivity: one is the Fukui reaction indices for a molecule, and the other is the minimum energy paths of hydrogen transition reaction between drug molecule and FeO-Porphyrin ring part on the CYP metabolic reaction. The Fukui indices are obtained numerically by using the familiar population analysis method in quantum chemical calculations. We performed the assessments of some population analyses to clarify the numerical behaviour clearly and then evaluated the potential of the reactivity of drug molecule. On the other hand, in the analysis of the minimum energy path for the CYP metabolic reaction, we performed the nudged elastic band (NEB) calculations for the hydrogen transition reaction in the first step of the CYP metabolic reaction. We report the findings for the reactivity from the Fukui indices method and also show the NEB results for the reaction paths.
Tunneling Dynamics of interacting bosons in a quantum seesaw potential
Authors: Dutta Sunayana , Chatterjee Budhaditya , Mishra Pankaj Kumar , Lode Axel U. J. , Tsatsos Marios C. , Basu Saurabh 
Published: October 2019

Abstract
We study the tunneling dynamics of N = 10 one-dimensional interacting bosons confined in a temporally driven double well potential that imitates a quantum seesaw and how we can manipulate these dynamics by changing the drive of the seesaw potential. We emulate the seesaw with a driven double well potential and consider two driving protocols: an harmonic constant-frequency drive and a chirped drive with linearly increasing frequency. We consider the time-dependent many-body Schrödinger equation of a repulsively interacting quasi-one-dimensional few-boson system. We solve it by using the multiconfigurational time-dependent Hartree method for bosons (MCTDHB) as implemented in the MCTDH-X software. For an harmonic drive and at small values of the driving amplitude, the dynamics of the particles become very slow rendering a stationary-like state. In a phase-space picture the population imbalance between the wells follows a trajectory which is restricted to a comparatively small region of space. For an harmonic drive at intermediate amplitudes, the dynamics become periodic in nature, implying that the bosons populate each of wells periodically. At comparatively large amplitudes of the harmonic drive, the dynamics show features of chaos in phase-space representation. For the chirped drive with a driving frequency increasing linearly in time, the imbalance of the atoms in the seesaw, however, has a temporal evolution that is faster for certain frequency ranges. The tunneling dynamics in such cases, for small amplitudes, show the appearance of quasi-periodicity with simultaneously present slow and fast oscillations. Increasing the amplitude of the chirped drive, we observe that the dynamics, although being periodic, become severely damped in their amplitude. Our study establishes that by tuning the temporal evolution of the quantum seesaw, a precise control of tunneling dynamics of the correlated bosons can be achieved. Since harmonic driving and chirp frequency modulation of the seesaw are experimentally achievable, our simulations can be experimentally realized in laboratories dealing with cold atomic gases.
Towards a mean-field kinetic model of electroweak baryogenesis
Authors: Montessori Andrea , Surungan Tasrief , Succi Sauro 
Published: October 2019

Abstract
We explore the dynamic symmetry breaking between the mass of two annihilating species entrapped within a condensing droplet of a third phase-changing species. The symmetry breaking is induced by different diffusivities and/or diffebet source terms acting at the droplet interface. Potential implications for the problem of electroweak baryogenesis are sketched out.
Construction of a one-parameter family of isospectral potential to study resonances in weakly bound halo nuclei
Authors: Hasan Mahamadun , Surungan Tasrief , Abdul Khan Md 
Published: October 2019

Abstract
In this paper, a novel theoretical scheme is presented to investigate resonant levels in weakly bound nuclear systems by the use of isospectral potentials. In this scheme, a new potential is constructed which is strictly isospectral with the original shallow-well potential and has properties which are desirable to make the calculation of resonances more accurate and easier. To demonstrate the effectiveness of the method, the first 0+ resonance in the neutron-rich 22C is calculated assuming a three-body (20C+n+n) cluster model.
Impact of Non-linear Boson Self-interaction on Dark Stars Properties
Authors: Rahmansyah A. , Sulaksono A. 
Published: October 2019

Abstract
We study the properties of dark stars using non-linear boson self-interaction models. These stars are compact objects formed from bosonic dark matter. We focus on the properties of dark stars such as the mass and radius relation, tidal deformation, and moment of inertia. In this work, bosonic dark particle mass is set to be 300 MeV and 400 MeV. The bosonic self-interaction potential models are |ϕ|4, cosh-Gordon and Liouville which have the same behavior at low densities but relative difference at high densities. Coupling constants on the corresponding self-interaction potentials are determined by the result of numerical simulations CCDM which requires ratio total cross-section to dark particle mass in the range of

0.1

c

m
2

g

≤

σ
M

≤
1

c

m
2

g

.
Testing Modified Gravity Theories by Constraining the Theories Parameter Using Radius and Mass Observations of Brown Dwarfs
Authors: Rosyadi A. S. , Sulaksono A. 
Published: October 2019

Abstract
Modified Gravity (MOG) theories modify Poisson equation in the Newtonian limit. This MOG is also important as test-bed to analyze whether General Relativity (GR) is consistent with observations. We investigate the mass and radius of Brown Dwarfs predicted by modified Poisson equation from Beyond Horndeski (BH) and Eddington-Inspired-Born-Infeld (EiBI) theories. Brown Dwarfs are sub-stellar objects that are difficult to be detected because of their low luminosity. One of the most important properties of brown dwarfs which recently observed by Johnson and Montet[1] are radii and masses. In this note, we derive the equation of state of the stars analytically, wherein electrons part, we use exact non-relativistic degenerate ideal Fermi gas result. We also derive modified hydrostatic stellar equation predicted by MOG theories and solve them numerically to obtain their profile and mass-radius relation for each parameter on both MOG theories. We compare our theoretical results with the ones obtained Johnson and Montet [1].
Tidal Love Numbers of Fermionic Dark Stars
Authors: Wahidin A. B. , Sulaksono A. 
Published: October 2019

Abstract
Dark star is a hypothetical stellar compact object composed of dark particles which clumped together due to self-interaction among dark particles. Tidal Love numbers from binary stars are potential observables for studying the internal structure of the stars. The Tidal Love numbers can be deduced from the gravitational wave of the coalescence or inspiral of binary stars. The ground base interferometer can measure the corresponding gravitational wave. In this work, we study the equation of state, mass-radius relation, electric, magnetic and surficial tidal love numbers of dark stars. We obtain that Tidal Love numbers are not too sensitive to study the role of scalar boson exchange and the impact of the mass of the dark particle in dark matter equation of state.
Finite Difference Method For Laplace Equation In Irregular Domain
Authors: Juarlin E. 
Published: October 2019

Abstract
Laplace equation on irregular domain has been solved by finite difference method. The program for calculating distribution of electric potential inside has been developed. Symmetrical Dirichlet boundary condition and Cartesius Coordinates are applied. A trapezoid and a quarter of a circle are chosen as irregular domain example. The contour of electric potential shows symmetrical result to its domain. The convergence and stability output program shows a good result.
Demonstrating open superstring amplitude relationship with Yang-Mills theory based on dual model limit
Authors: Barreiro Luiz Antonio , Amaro de Faria A C , Canone A M 
Published: October 2019

Abstract
This paper demonstrates the relationship between superstrings, Yang-Mills fields, and dual models. We discovered a novel and profound connection between these theories and their respective prescriptions for the calculation of scattering amplitudes, which directly demonstrates the duality between Field Theory and String Theory in a novel manner.
“Thick Section” Gram Stain Yields Improved Detection of Organisms in Tissue Sections of Cystic Neutrophilic Granulomatous Mastitis
Authors: Sangoi Ankur R 
Published: October 2019

Abstract

Objectives
Cystic neutrophilic granulomatous mastitis (CNGM) is an uncommon subtype of granulomatous mastitis featuring epithelioid histiocytes/neutrophils rimming discrete cystic spaces. When present, gram-positive bacteria (typically Corynebacterium species) are identified within these cystic spaces, although they can be difficult to appreciate on tissue sections.

Methods
Based on pilot gram-stained tissue sections of CNGM cases cut on 6 μm thickness (in which bacterial organisms were more readily identifiable) instead of the traditional 4 μm, a formal comparative analysis of 19 CNGM cases was performed on parallel 6-μm (“thick”) vs 4-μm sections from one representative block per case.

Results
Biopsies (n = 17) and excisional specimens (n = 2) from 19 CNGM cases were included. Gram-positive palisaded rods were identified in seven cases using 4-μm sections and in 11 cases using 6-μm sections (sensitivity of 37% vs 58% in identifying organisms). Among all seven cases of organisms seen on the 4-μm section Gram stain, the paired 6-μm section Gram stain showed a higher number of and more readily identifiable bacteria.

Conclusions
Thick section Gram stain of representative tissue blocks performed at 6 μm improves both detection rate and ease of identification of gram-positive organisms in CNGM.
Evidence-based development of a nephrotoxic medication list to screen for acute kidney injury risk in hospitalized children
Authors: Goswami Elizabeth , Ogden Richard K , Bennett William E , Goldstein Stuart L , Hackbarth Richard , Somers Michael J G , Yonekawa Karyn , Misurac Jason 
Published: October 2019

Abstract

Purpose
Medications are commonly associated with acute kidney injury (AKI). However, in both clinical practice and research, consideration of specific medications as nephrotoxic varies widely. The Nephrotoxic Injury Negated by Just-in-time Action quality improvement collaborative was formed to focus on prevention or reduction of nephrotoxic medication-associated AKI in noncritically ill hospitalized children. However, there were discrepancies among institutions as to which medications should be considered nephrotoxic. The collaborative convened a Nephrotoxic Medication (NTMx) Subcommittee to develop a consensus for the classification of nephrotoxic medications.

Summary
The NTMx Subcommittee initially included pediatric nephrologists, a pharmacist, and a pediatric intensivist. The committee reviewed NTMx lists from the collaborative and identified changes from the initial NTMx list. The NTMx Subcommittee conducted a literature review of the disputed medications and assigned an evidence grade based on the reported association with nephrotoxicity and the quality of the data. The association between medication exposure and AKI was also determined using administrative data from the Pediatric Health Information Systems database. The NTMx Subcommittee then came to a majority consensus regarding which medications should be included on the list. The subcommittee’s recommendations were presented to the larger collaborative for approval, and consensus was achieved. The list continues to be reviewed and updated annually.

Conclusion
Formation of a multicenter quality-improvement initiative exposed current limitations as to which medications are considered nephrotoxic in clinical and research settings and presented an opportunity to approach this problem using an evidence-based process. A consensus definition of nephrotoxic-medication exposure was achieved.
Higher naloxone dosing may be required for opioid overdose
Authors: Bardsley Russell 
Published: October 2019

Abstract

Purpose
Carfentanil is a synthetic opioid with an estimated potency that is 10,000 times more than that of morphine and 100 times more than that of fentanyl. Although there is a paucity of evidence, when considering the potency of carfentanil, it is reasonable to speculate that larger doses of naloxone may be required to resuscitate patients after carfentanil ingestion. This case report discusses the use of high-dose naloxone in 2 patients with suspected carfentanil overdose presenting to a small community hospital.

Summary
Two patients with suspected carfentanil overdose presented to a 30-bed emergency department at a community hospital in New Hampshire. Cyanosis and respiratory distress were noted in both instances, and airway intervention was ultimately deemed necessary. Patient 1 required a total of 12 mg of naloxone to be successfully resuscitated, while patient 2 required a total of 10 mg for resuscitation.
Both patients were successfully resuscitated with high doses of naloxone. The use of high-dose naloxone prevented the need for intubation in these patients.

Conclusion
While more robust studies should be considered, emergency personnel should be comfortable using higher-than-standard doses of naloxone in appropriate cases.