bluuebunny/crossref_metadata_2025_split huggingface dataset:
Caracterização geológica, geoquímica e aerogeofísica dos granitoides arqueanos da porção sul do Domínio Rio Maria
Authors: Almeida José De Arimatéia Costa de , Oliveira Vinícius Eduardo Silva de , Rocha Jorge Luis Sousa , Feio Gilmara Regina De Lima , Rocha Marcílio Cardoso , Rocha Karla Petrúcia Pedroso da 
Published: August 2020

As informações geológicas da porção sul do Domínio Rio Maria, Província Carajás (sudeste do Cratón Amazônico), são escassas. Dados aerogeofísicos e de campo permitiram definir a assinatura aerogeofísica das unidades geológicas, identificar enxames de diques (NE-SW, NW-SE e N-S) e reconhecer distintos padrões estruturais (NE-SW, NW-SE e N-S e E-W) na porção sul do Domínio Rio Maria. Três grupos de granitoides foram distinguidos nessa região: 1) associação tonalítica-trondhjemítica; 2) leucomonzogranitos e; 3) leucogranodioritos. Observa-se aumento do conteúdo de SiO2, K2O e Rb e das razões alcáli-feldspato/plagioclásio, K2O/Na2O, FeOt/(FeOt + MgO), e decréscimo das proporções de TiO2, Al2O3, Fe2O3t,CaO, MgO, Sr e Zr no sentido grupo 1 → grupo 2. Os grupos 1 e 3 registram similaridades geoquímicas. No entanto, o grupo 1 exibe teores mais elevados de CaO e mais baixos de K2O e Rb em relação ao grupo 3. Essas rochas apresentam moderada a alta razão La/Yb e ausência de anomalia de európio. Já o grupo 2 mostra enriquecimento dos (ETRL) e moderado fracionamento dos (ETRP), com moderada a pronunciada anomalia negativa de Eu. O grupo 1 representa as rochas mais antigas do Tonalito Arco Verde (2,96 ± 0,02 Ga), enquanto as rochas dos grupos 2 e 3 mostram fortes analogias com os leucogranitos potássicos e com os leucomonzogranitos-granodioritos ricos em Ba e Sr do Domínio Rio Maria, respectivamente. A integração dos dados multifontes permite assumir que a granitogênese arqueana do Domínio Rio se estende por pelo menos 80 km a sul da cidade de Redenção, e as séries granitoides aflorantes nessa porção são análogas àquelas presentes na região de Pau D’Arco, Rio Maria, Bannach e Xinguara.
LLAP Band Structure and Intense Lake-Effect Snowfall Downwind of Lake Ontario: Insights from the OWLeS 7–9 January 2014 Event
Authors: Bergmaier Philip T. , Geerts Bart 
Published: August 2020

AbstractModeling and observational studies stemming from the 2013–14 Ontario Winter Lake-Effect Systems (OWLeS) field campaign have yielded much insight into the structure and development of long-lake-axis-parallel (LLAP) lake-effect systems over Lake Ontario. This study uses airborne single- and dual-Doppler radar data obtained during two University of Wyoming King Air flights, as well as a high-resolution numerical model simulation, to examine and contrast two distinctly different LLAP band structures observed within a highly persistent lake-effect system on 7–9 January 2014. On 7 January, a very cold air mass accompanied by strong westerly winds and weak capping aloft resulted in a deep, intense LLAP band that produced heavy snowfall well inland. In contrast, weaker winds, weaker surface heat fluxes, and stronger capping aloft resulted in a weaker LLAP band on 9 January. This band was blocked along the downwind shore and produced only light snowfall closer to the shoreline. Although the two structures examined here represent opposite ends of a spectrum of LLAP bands, both cases reveal a well-organized mesoscale secondary circulation composed of two counterrotating horizontal vortices positioned on either side of a narrow updraft within the band. In both cases, this circulation traces back to a shallow, baroclinic land-breeze front originating along a bulge in the lake’s southern shoreline. As the band extends downstream and the low-level baroclinity weakens, buoyancy increases within the band—driven in part by cloud latent heating—leading to band intensification and a deeper, stronger, and more symmetric secondary circulation over the lake.
WRF Modeling of Deep Convection and Hail for Wind Power Applications
Authors: Letson F. , Shepherd T. J. , Barthelmie R. J. , Pryor S. C. 
Published: August 2020

AbstractDeep convection and the related occurrence of hail, intense precipitation, and wind gusts represent a hazard to a range of energy infrastructure including wind turbine blades. Wind turbine blade leading-edge erosion (LEE) is caused by the impact of falling hydrometeors onto rotating wind turbine blades. It is a major source of wind turbine maintenance costs and energy losses from wind farms. In the U.S. southern Great Plains (SGP), where there is widespread wind energy development, deep convection and hail events are common, increasing the potential for precipitation-driven LEE. A 25-day Weather Research and Forecasting (WRF) Model simulation conducted at convection-permitting resolution and using a detailed microphysics scheme is carried out for the SGP to evaluate the effectiveness in modeling the wind and precipitation conditions relevant to LEE potential. WRF output for these properties is evaluated using radar observations of precipitation (including hail) and reflectivity, in situ wind speed measurements, and wind power generation. This research demonstrates some skill for the primary drivers of LEE. Wind speeds, rainfall rates, and precipitation totals show good agreement with observations. The occurrence of precipitation during power-producing wind speeds is also shown to exhibit fidelity. Hail events frequently occur during periods when wind turbines are rotating and are especially important to LEE in the SGP. The presence of hail is modeled with a mean proportion correct of 0.77 and an odds ratio of 4.55. Further research is needed to demonstrate sufficient model performance to be actionable for the wind energy industry, and there is evidence for positive model bias in cloud reflectivity.
Skillful All-Season S2S Prediction of U.S. Precipitation Using the MJO and QBO
Authors: Nardi Kyle M. , Baggett Cory F. , Barnes Elizabeth A. , Maloney Eric D. , Harnos Daniel S. , Ciasto Laura M. 
Published: August 2020

AbstractAlthough useful at short and medium ranges, current dynamical models provide little additional skill for precipitation forecasts beyond week 2 (14 days). However, recent studies have demonstrated that downstream forcing by the Madden–Julian oscillation (MJO) and quasi-biennial oscillation (QBO) influences subseasonal variability, and predictability, of sensible weather across North America. Building on prior studies evaluating the influence of the MJO and QBO on the subseasonal prediction of North American weather, we apply an empirical model that uses the MJO and QBO as predictors to forecast anomalous (i.e., categorical above- or below-normal) pentadal precipitation at weeks 3–6 (15–42 days). A novel aspect of our study is the application and evaluation of the model for subseasonal prediction of precipitation across the entire contiguous United States and Alaska during all seasons. In almost all regions and seasons, the model provides “skillful forecasts of opportunity” for 20%–50% of all forecasts valid weeks 3–6. We also find that this model skill is correlated with historical responses of precipitation, and related synoptic quantities, to the MJO and QBO. Finally, we show that the inclusion of the QBO as a predictor increases the frequency of skillful forecasts of opportunity over most of the contiguous United States and Alaska during all seasons. These findings will provide guidance to forecasters regarding the utility of the MJO and QBO for subseasonal precipitation outlooks.
Mirror therapy simultaneously combined with electrical stimulation for upper limb motor function recovery after stroke: a systematic review and meta-analysis of randomized controlled trials
Authors: Saavedra-García Alberto , Moral-Munoz Jose A , Lucena-Anton David 
Published: August 2020

Objective: To evaluate the current evidence on the effectiveness of simultaneous combination of mirror therapy and electrical stimulation in the recovery of upper limb motor function after stroke, compared with conventional therapy, mirror therapy or electrical stimulation isolated. Data sources: Articles published in PubMed, Web of Science, Scopus, Physiotherapy Evidence Database (PEDro), Cochrane Central register of controlled trials and ScienceDirect up to July 2020. Review methods: The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed. Methodological quality was assessed using the PEDro tool. The RevMan 5.4 statistical software was used to obtain the meta-analysis, through the standardized mean difference and 95% confidence intervals (CI), and to evaluate the risk of bias. The GRADE approach was employed to assess the certainty of evidence. Results: Eight articles were included in this systematic review, seven were included in the meta-analysis. A total of 314 participants were analyzed. The overall quality of the articles included in this review was good. There was no overall significant mean difference on upper limb motor function after stroke using the Upper-Extremity Fugl-Meyer Assessment by 1.56 (95% CI = –2.08, 5.20; P = 0.40; moderate-certainty evidence) and the Box and Block Test results by 1.39 (95% CI = –2.14, 4.92; P = 0.44; high-certainty evidence). There was overall significant difference in the Action Research Arm Test by 3.54 (95% CI = 0.18, 6.90; P = 0.04; high-certainty evidence). Conclusion: Direct scientific evidence about the effectiveness of the combined therapy of mirror therapy and electrical stimulation simultaneously for the improvement of the upper limb motor function after stroke is lacking. Further high-quality and well-designed research is needed.
A new case of myelodysplastic syndrome associated with t(3;3)(q21;q26) and inv(11)(p15q22)
Authors: Monti Valentina , Bagnoli Filippo , Bolli Niccolo’ , Vittoria Laura , Stioui Sabine , Moiraghi Maria Luisa , Pruneri Giancarlo , Testi Maria Adele 
Published: August 2020

Introduction: Myeloid malignancies are associated with a number of recurrent and sporadic rearrangements that may be oncogenic by ensuring growth advantage and/or increased survival. t(3;3)(q21;q26) has been recognized as a recurrent abnormality in myelodysplastic syndromes (MDS) with poor prognostic significance. Inversion of chr(11) engendering NUP98-DDX10 chimeric product is sporadic and usually associated with diseases with poor prognosis (therapy-related myeloid neoplasm). To date, these cytogenetic abnormalities have been described as isolated events. Case description: We report the first case of an 80-year-old man with high-risk MDS harboring a translocation t(3,3)(q21q26) jointly with an inv(11)(p15q22) detected by fluorescent in situ hybridization analysis and conventional cytogenetic techniques. Conclusion: A similar pattern of acquisition was never described before in MDS. The coexistence of two independent, high-risk oncogenic, rare events in the same clone suggests that there may be a functional constraint for synergy between the two events, leading to a proliferative advantage and suggests the utility of extended genotyping in myeloid malignancies.
Effect of Visit Frequency of Pharmacist-Led Diabetes Medication Management Program
Authors: Frederick Amy , Juan Joyce , Ivy Delaney , Maldonado Yolanda Munoz 
Published: August 2020

Background: Pharmacists have a positive effect on clinical outcomes in chronic disease state management, however, few studies have evaluated the effect that frequency of visits may have on diabetes biomarkers such as hemoglobin A1c and blood pressure readings. Methods: Under the medication management program (MMP), patients with diabetes were seen monthly by pharmacists until early 2015, when time between visits was increased to every 3 months. A retrospective chart review was conducted to evaluate the primary outcome of the percent change in hemoglobin A1c and blood pressure after the change in visit frequency. Results: In the 303 patients enrolled, no statistical difference existed between the pre and post average A1c (p-value = 0.10). The intermediate average A1c was statistically lower from the preintervention mean A1c (p-value = 0.001) but not from the postintervention mean A1c (p-value = 0.30). No statistical differences were seen between systolic blood pressure and diastolic blood pressure. Conclusion: Patients who have been seen by a clinical pharmacist more frequently (every month or every other month) for several years may be able to maintain their reduction in A1c with less-frequent visits (every 3 to 6 months).
Role of Physiotherapy in Hospice Care of Patients with Advanced Cancer: A Systematic Review
Authors: Vira Prina , Samuel Stephen Rajan , Amaravadi Sampath Kumar , Saxena PU Prakash , Rai PV Santosh , Kurian Jestina Rachel , Gururaj Rachita 
Published: August 2020

Objective: To review the role of physiotherapy and its effects in hospice care of patients with advanced cancer. Methods: A comprehensive literature search was performed in PubMed, Scopus, Web of Science, CINAHL and PEDro. The search strategy was devised, articles were screened, and 2 independent reviewers conducted data extraction. Eligible studies were methodologically assessed for quality rating using modified Downs and Black’s checklist. The extracted data was summarized according to site/stage of cancer, details of intervention, outcome measures and the results. Result: The total number of screened articles were 2102, out of which 9 were identified as suitable for the purposes of comprehensive review. The studies included exercise therapy, massage therapy, relaxation therapy, compression bandaging and use of TENS as the various physiotherapy interventions under consideration. Studies were generally of low to moderate quality. A broad range of outcomes were employed including physical symptoms like loss of function, pain, fatigue, edema, sleep disturbances and quality of life. The findings of the studies supported the benefits of the interventions. Conclusion: A structured exercise protocol, massage therapy, TENS and compression bandaging are useful in alleviating the symptoms experienced by patients with advanced cancer in hospice care. The reduced symptom burden has reflected as an improvement in their quality of life. However, there is a further need for high quality studies to strengthen the findings of this review.
68-months progression-free survival with crizotinib treatment in a patient with metastatic ALK positive lung adenocarcinoma and sarcoidosis: A case report
Authors: Tanriverdi Ozgur , Tarimer Mehmet L , Pak Ceren D , Uylas Selcuk , Alkan Ali , Celik Ozgur Ilhan , Kilic Rabia M , Zeybek Arife 
Published: August 2020

Introduction Lung cancer still ranks first among the most common and most lethal cancers today. The most common subtype is non-small cell lung cancer, and in this group, adenocarcinoma has the worst prognosis. EGFR, ROS1 and ALK-EML4 gene fusion mutations are common in non-small cell lung cancer. Case report A 62-year-old non-smoker patient applied in February 2014 for purulent sputum and pain in the chest. Computed tomography revealed a 39x33 mm mass in the right hilum, multiple parenchymal nodules in the bilateral lung and mediastinal multiple enlarged lymph nodes. The patient was admitted to the lung adenocarcinoma as a result of a biopsy from the mass in the hilum, and sarcoidosis was diagnosed by mediastinal lymph node biopsy. Management & outcome After 4 cycles of carboplatin-pemetrexed for the first line treatment, progression was detected. The patient did not have EGFR and ROS1 mutations. The patient with positive ALK fusion mutation started crizotinib treatment in July 2014. The patient's last response assessment was in March 2020, with 68-progression-free disease with crizotinib. No toxicity was observed except for Grade 1 weakness. No dose changes were made. The patient is still being followed up without brain metastasis under the treatment of crizotinib. Discussion In this article, we wanted to share our experience of crizotinib in a 68-months progression-free survival in a 62-years old non-smoking female patient with metastatic lung adenocarcinoma who is also diagnosed with sarcoidosis.
Intrastromal corneal ring segment implantation in paracentral keratoconus with perpendicular topographic astigmatism and comatic axis
Authors: Fernández-Vega-Cueto Luis , Lisa Carlos , Alfonso-Bartolozzi Belén , Madrid-Costa David , Alfonso José F 
Published: August 2020

Purpose: To evaluate the outcomes of implanting intrastromal corneal ring segment (ICRS) using two different strategies in a specific paracentral keratoconus phenotype. Methods: Eighty-nine eyes with paracentral keratoconus with perpendicular topographic astigmatism and comatic axes were evaluated before and after implanting a 150° arc-length ICRS. Patients were divided into two groups according to the axis where the ICRS was implanted: Group I: comatic axis and Group II: flat topographic axis. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refractive errors, and root mean square (RMS) for coma-like aberration were recorded. The postoperative follow-up was 1 year. Results: Mean UDVA (logMAR) changed from 0.49 ± 0.37 preoperatively to 0.30 ± 0.32 6 months afterwards ( p < 0.001) in the group I and from 0.53 ± 0.34 to 0.37 ± 0.35 ( p < 0.001), in the group II. Mean CDVA in group I changed from 0.11 ± 0.18 preoperatively to 0.06 ± 0.14 6 months after surgery ( p < 0.001). In group II the improvement did not reach statistical significance (from 0.09 ± 0.10 to 0.07 ± 0.09; p = 0.06). No eyes lost lines of CDVA in group I. Eight eyes (15.7%) lost lines of CDVA in group II. The spherical equivalent decreased after surgery in both groups ( p < 0.001). The RMS for corneal coma-like aberration only decreased in the group I ( p < 0.001). Conclusion: Both strategies provided safe and effective visual and refractive outcomes in the specific keratoconus phenotype analyzed. The orthopedic strategy provided better visual outcomes than the refractive one.
Transnational social work: Challenging and crossing borders and boundaries
Authors: Schrooten Mieke 
Published: August 2020

Summary Interest in transnationality and borders has expanded considerably within several academic disciplines over the last decades. This paper explores the way this transnational perspective has been developed within social work. It then identifies a number of gaps in current transnational social work research and proposes four avenues for additional inquiry that allow for an unbounding of how social work is theorised and the development of a perspective that recognises social work’s role beyond a bounded national state. Findings Borders and cross-border processes and structures pose essential challenges to social work research and practice. State borders may be opening to certain cyber, social and economic functions, but are at the same time (re-)closing to other security and political functions. Moreover, more metaphorical and symbolic boundaries are also strengthening. A transnational turn in the educational, theoretical and practical field of social work requires a move away from the conventional local and sedentary conceptualisation of society and social life that is still omnipresent today, in order to develop a social work that recognises and explores, as well as challenges and crosses borders and boundaries. Applications Despite the increase of transnational lifestyles, social problems and social work practices, the body of knowledge in this domain is as yet rather limited and fragmented. The applications of this article concern a theoretical contribution to this body of knowledge, which can also be used in curricula for social work education. Moreover, it contributes to a move away from the ‘methodological nationalism’ at work in social work.
Hospital care for opioid use disorder in pregnancy: Challenges and opportunities identified from a Minnesota survey
Authors: Dopp Alana , Zabel Thornton Morgan , Kozhimannil Katy , Jones Cresta W , Greenfield Brenna 
Published: August 2020

Objectives: The prevalence of opioid use disorder continues to rise in the United States, with a simultaneous increase in the diagnosis of both opioid use disorder during pregnancy and neonatal opioid withdrawal syndrome. Despite these increases in pregnancy-related care, little is known about hospital policy and policy implementation related to opioid use disorder in pregnancy. In addition, it is unknown whether policies might differ in rural or urban hospitals. To better examine these issues, Minnesota hospitals were surveyed regarding the existence and implementation of policies related to opioid use disorder in pregnancy and whether any policy implementation challenges had been identified. Methods: From August to December 2017, the research team contacted all Minnesota hospitals that offered obstetric services ( n = 82) to survey challenges to implementing policies for opioid use disorder during pregnancy, among other questions. Fifty-nine hospitals had respondents (primarily obstetric department supervisors) who provided information about policy implementation challenges for a 72% response rate. Qualitative responses were analyzed using qualitative description and according to hospital location: metropolitan (urban), micropolitan (rural), or non-core (rural). Results: Ninety-one percent of respondents said that they had pregnancies affected by opioid use disorder at their hospital within the last year. Four major challenges to policy implementation were identified in qualitative responses: (1) provider consensus, (2) patient response to policy, (3) lack of resources, and (4) low frequency of occurrence. All four challenges were more frequently identified by respondents at rural hospitals compared to urban hospitals. Conclusion: This study identified challenges in standardizing hospital care for pregnancies affected by opioid use disorder, and these challenges were identified more frequently in rural locations. These non-urban hospitals may require increased state and federal support and funding.