bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Simplified Procedure for Biologically Oriented Alveolar Ridge Preservation: Clinical and Histological Findings From a Case Report
Authors: Pramstraller Mattia , Farina Roberto , Simonelli Anna , Götz Werner , Trombelli Leonardo 
Published: September 2020

IntroductionA recent systematic review failed to identify one approach for alveolar ridge preservation (ARP) with superior outcomes compared with the others. The present case report presents a novel, simplified technique for ARP, namely the Biologically‐oriented Alveolar Ridge Preservation (BARP), based on socket grafting and sealing.Case PresentationAfter extraction of tooth #19, the socket was filled with a collagen sponge up to 4‐5 mm from the most coronal extension of the bone crest (deep collagen layer). A bovine‐derived xenograft was placed on top of the collagen sponge to fill the coronal part of the socket (graft layer). Socket sealing was then performed by placing a collagen sponge over the exposed portion of the graft (superficial collagen layer), and the wound healed by secondary intention. At implant insertion (4 months after ARP), limited reduction in bone width and no vertical change in ridge height were observed. Histological analysis of a biopsy specimen retrieved during implant site preparation showed a gradient ranging from interconnected trabeculae of mature, lamellar bone in the apical portion to cancellous bone incorporating a modest number of remodeled graft granules in the central portion. In the coronal portion, non‐mineralized tissue with sparse isles of newly formed cancellous bone and residual graft granules was found.ConclusionThe present case report indicates that BARP might provide ideal conditions for preserving the pre‐existing alveolar ridge dimensions following tooth extraction while restricting any potential interference of the graft biomaterial with bone healing dynamics to the coronal part of the socket.
A challenging diagnosis of a nonsecretor plasma cell dyscrasia with pleomorphic plasmablastic morphology
Authors: Van Landeghem Stijn , Capiau Sara , Bayart Jean‐Louis , Vlummens Philip , Van Dorpe Jo , Van Roy Nadine , Philippé Jan 
Published: September 2020

AbstractThis report highlights the importance of integrating clinical, radiological, genetic, and pathological laboratory findings to make a correct diagnosis especially with challenging and rare entities.
Getting to the heart of childhood empathy: Relations with shyness and respiratory sinus arrhythmia
Authors: MacGowan Taigan L. , Schmidt Louis A. 
Published: September 2020

AbstractAlthough prior studies have found that shyness and empathy are inversely related and that well‐regulated children tend to express empathic behaviors more often, little work has assessed combinations of these factors in predicting affective and cognitive empathy in early childhood. The authors examined relations among shyness, resting respiratory sinus arrhythmia (RSA), and observed affective and cognitive empathy in a sample of 130 typically developing children (Mage = 63.5 months,SD = 12.2; 62 males). Shyness was assessed by observing children's behaviors during a self‐presentation task, and this observed measure was then combined with a maternal report of children's temperamental shyness. Children's shyness predicted lower levels of both affective and cognitive responses to an experimenter feigning an injury. Resting RSA moderated the relation between children's shyness and observed empathy such that relatively higher shyness combined with lower RSA levels conferred the lowest levels of cognitive empathy. Children who were relatively low in shyness exhibited similar levels of cognitive empathy across different levels of RSA. However, this moderation was not found when predicting children's affective empathy. Our results suggest that not all shy children are alike in terms of their empathic behaviors: shy children who are physiologically dysregulated appear to have difficulties exploring and/or processing others’ pain.
Mental imagery training in older adults: Which are benefits and individual predictors?
Authors: Vranic Andrea , Martincevic Marina , Borella Erika 
Published: September 2020

AbstractObjectivesStrategic memory training involves explicit instructions in mnemonic methods to improve recall. Mental imagery is considered among the most effective encoding strategies. The aim of the present study was to assess the benefits of a strategic memory training based on mental imagery (originally proposed by Carretti et al., 2007) and to further investigate its potentials. The study represents a replication in a new and independent cultural setting and features valuable methodological amendments, while it also examines individual predictors of training efficacy.DesignA sample of 91 older volunteers (age 61–88), divided in training and control group, participated in the training. Specific training gain in the immediate word list recall (criterion task), as well as transfer effects on Letter‐Number Sequencing (working memory [WM] task), long‐term recall and recognition (LTM tasks) were tested at the pretest and at the posttest.ResultsAnalysis of variance showed posttraining effects in immediate word recall and long‐term verbal recall, but no effects in WM task and long‐term recognition. Regression analysis showed age to be the only significant predictor in one task, the immediate word recall.ConclusionsOverall, proposed training can improve some aspects of memory performance by aiding in strategic use of mental imagery. Transfer to other tasks and contribution of individual predictors to training efficacy results limited, however. It seems that training benefits are evident when task similarity enables transfer‐appropriate processing (as evidenced in gains of both recall tasks), while training efficacy relies on individual characteristics which contribute to the execution of some task components.
Diagnostic value of exosomal circMYC in radioresistant nasopharyngeal carcinoma
Authors: Luo Yanwei , Ma Jinqi , Liu Fengxia , Guo Jie , Gui Rong 
Published: September 2020

AbstractBackgroundThe relationship between circulating exosomal circular RNA (circRNA) and prognosis of patients with nasopharyngeal carcinoma (NPC) remain unknown. This study focused on the expression of exosomal circMYC and its relationship with the recurrence and prognosis of patients with NPC.MethodsThe circulating exosomes were obtained from 210 patients with NPC. Quantitative polymerase chain reaction, 5‐ethynyl‐2′‐deoxyuridine (EdU) staining, colony formation, and bioinformatic analysis were performed.ResultsCirculating exosomal circMYC was significantly increased in patients with NPC and was associated with tumor size, lymph node metastasis, TNM stage, survival rate, and disease recurrence. Gain‐functional and loss‐functional experiments revealed that overexpression of circMYC promoted cell proliferation and reduce radiosensitivity, while knockdown of circMYC inhibited cell proliferation and enhanced radiotherapy.ConclusioncircMYC is an oncogene in NPC cells and can enhance the radiotherapy resistance of NPC cells. Circulating exosomal circMYC can be used as a potential therapeutic target for NPC.
Concluding commentary: Treating perfectionism transdiagnostically with an eye on the future
Authors: Podina Ioana R. 
Published: September 2020

AbstractThe current piece of work is a commentary section for the special issue regarding the treatment of perfectionism. It discusses analytically the similarities and the differences between the six clinical case formulations included in the special issue to emphasize that there are different routes to beneficial outcomes. All the psychotherapeutic approaches included here are either transdiagnostic or have transdiagnostic applications. As such, the second part of the commentary focuses on the transdiagnostic future of the treatment of perfectionism. Concluding remarks evidence a collection of clinical case studies covering multiple forms of psychotherapy and an integrating overview of the literature from which practitioners can extract best practices examples. Though there is still a lot to be done with and for interventions on perfectionism, the current collection of case studies is a good starting point.
Alcoholic beverage consumption, smoking habits, and periodontitis: A cross‐sectional investigation of the NutriNet‐Santé study
Authors: Hamdi Zeineb , Detzen Laurent , Fessi Sabrine , Julia Chantal , Hercberg Serge , Czernichow Sébastien , Boillot Adrien , Touvier Mathilde , Bouchard Philippe , Andreeva Valentina A. , Carra Maria Clotilde 
Published: September 2020

AbstractBackgroundRecent evidence suggests that dietary habits influence the development and severity of periodontitis. The present cross‐sectional study evaluated the association between different types and quantity of alcoholic beverage consumption (alone and interacting with smoking) and the probability to suffer from severe periodontitis in the French e‐cohort NutriNet‐Santé.MethodsThe study population consisted of 35,390 adults (mean age: 49.04 ± 13.94 years), who filled oral health questionnaires and completed at least three non‐consecutive 24‐hour dietary records. Data on type and frequency of alcoholic beverage consumption were obtained from a semi‐quantitative self‐reported alcohol frequency questionnaire; the daily quantity (g/day) was estimated from the 24‐hour dietary records. The probability of severe periodontitis (main dependent variable) was assessed by calculating the modified periodontal screening score (mPESS) from selected questions.ResultsA total of 7263 individuals (20.5%) presented a high probability of suffering from severe periodontitis (high‐mPESS). After adjusting for confounding factors, the frequency of alcoholic beverage consumption was significantly higher among high‐mPESS group than their low‐mPESS counterparts, especially for hard liquor/spirits (1.9 ± 1.4 days/week for high‐PESS versus 1.6 ± 1.1 days/week the low‐PESS [P < 0.0001]). The mean daily quantity of ethanol was also higher in high‐mPESS versus low‐mPESS individuals (11.2 ± 15.6 versus 7.9 ± 12.3 g/day;P = 0.011). A stronger association with self‐report severe periodontitis was noted when alcohol consumption exceeding > 20 g/day for women and > 30 g/day for men was combined with smoking habit (OR = 7.30 [95% CI: 6.1‐8.73]).ConclusionThe present results support an association between alcoholic beverage consumption and self‐report severe periodontitis, particularly when it is associated with current smoking.
Technological, nutritional, and sensory properties of durum wheat fresh pasta fortified with Moringa oleifera L. leaf powder
Authors: Simonato Barbara , Tolve Roberta , Rainero Giada , Rizzi Corrado , Sega Davide , Rocchetti Gabriele , Lucini Luigi , Giuberti Gianluca 
Published: September 2020

AbstractBACKGROUNDPasta is a staple food that is consumed worldwide and is an excellent product for the addition of ingredients rich in bioactive compounds. The fortification of pasta with such compounds could represent a healthy choice for consumers.RESULTSIn this study, fresh pasta was formulated by replacing durum wheat semolina with 0, 5, 10, and 15 g 100 g−1 of dried Moringa oleifera leaf powder (MOLP), rich in fibers, minerals, and antioxidant compounds. Increasing levels of MOLP influenced the technological and nutritional properties of wheat‐based fresh pasta. Moringa oleifera reduced the optimum cooking time, the swelling index and firmness, while increasing the cooking loss and adhesiveness. From a nutritional viewpoint, the inclusion of MOLP enhanced the phenol content, the antioxidant activity, and the mineral content of fresh pasta. The products obtained had good sensorial acceptability and can make several nutritional claims due to MOLP richness minerals.CONCLUSIONSThe fortification of fresh pasta with MOLP could represent a valuable strategy to increase the nutritional value of the product, preserving pasta technological properties without affecting sensory acceptability. © 2020 Society of Chemical Industry
Yttrium‐90 radiation segmentectomy for hepatic metastases: A multi‐institutional study of safety and efficacy
Authors: Padia Siddharth A. , Johnson Guy E. , Agopian Vatche G. , DiNorcia Joseph , Srinivasa Ravi N. , Sayre James , Shin David S. 
Published: September 2020

AbstractBackground and ObjectivesThis study assessed the outcomes of Yttrium‐90 (90Y) radiation segmentectomy for hepatic metastases unamenable to resection or ablation.Materials and MethodsOver 6 years, 36 patients with 53 tumors underwent segmental radioembolization. Patients were not candidates for surgical resection or thermal ablation. Malignancies included metastases from colorectal cancer (31%), neuroendocrine tumors (28%), sarcoma (19%), and others (22%). Eighty‐one percent of patients had undergone prior treatment with systemic chemotherapy. Ongoing systemic chemotherapy was continued. Toxicity, tumor response, tumor progression, and survival were assessed.ResultsThe median tumor size was 3.6 cm (range 1.2–6.1 cm). Adverse event rates were low, with no hepatic‐related Common Terminology Criteria for Adverse Events Grade 3 or 4 toxicity. Target tumor Response Evaluation Criteria in Solid Tumors disease control rate was 92% (28% partial response, 64% stable disease). For patients with enhancing tumors (n = 14), modified Response Evaluation Criteria in Solid Tumors target tumor objective response rate was 100%. During a median follow‐up of 12 months, target tumor progression occurred in 28% of treated tumors. Overall survival was 96% and 83% at 6 and 12 months, respectively.Conclusions90Y radiation segmentectomy for hepatic metastases demonstrates high rates of tumor control and minimal toxicity. Radiation segmentectomy should be considered for patients with metastatic hepatic malignancy who are not candidates for surgical resection.
Effects of Al‐Ni powder addition on dissimilar friction stir welding between AA7075‐T6 and 304 L
Authors: Muhamad M.R. , Jamaludin M.F. , Yusof F. , Mahmoodian R. , Morisada Y. , Suga T. , Fujii H. 
Published: September 2020

AbstractFriction stir welding between AA7075‐T6 aluminum alloy and 304 L stainless steel sheet metal was performed with the addition of Al−Ni powder between the joining interfaces to increase the joining performance. The welding tool was rotated at 200 min−1 to 800 min−1 with the constant traverse speed of 25 mm/min. The resulting joint interfaces were analyzed using a field emission‐scanning electron microscope and energy‐dispersive x‐ray spectroscopy analysis. The tensile strength was greater for the Al−Ni powder added specimens at the lower tool rotational speeds. The tensile strength of 360 MPa was obtained for the ‘with‐powder’ specimen as compared to 220 MPa for the ‘without‐powder’ specimen at the 200 min−1 tool speed. Electron microscope images of the stir zone showed a significant mixing of the Al−Ni powder with the base materials, increased contact at the interface, which resulted in increased joining strength at the lower tool rotational speeds. However, based on the images, intermetallic compound that may contribute to the joining strength in the vicinity of the interfacial region was not detected.
Kalman filter tracking of sequence spot centroid ablated by femtosecond laser
Authors: Wang Fubin , Liu Mengzhu , Wang Shangzheng 
Published: September 2020

AbstractIn the process of processing monocrystalline silicon by femtosecond laser, there is a phenomenon of derived plasma luminescence, which formed the time series spot. The laser spot image contains some effective information related to process parameters, such as ablation power of femtosecond laser, processing speed and so on. Through the comprehensive analysis of the geometric features of the sequential spot image, it can be used in the closed‐loop feedback system of micromachining based on the features of the plasma spot image. Because the spot centroid can be used to locate the spot position accurately, the sequential spot centroid obtained by gray centroid method was used as the sampling data, which was tracked by Kalman filter, and then the movement law of the spot was observed and analyzed. In this paper, the discrete linear Kalman filter algorithm is used to establish motion model of the spot centroid, and the next movement state of spot is predicted, and then the trajectory of the spot is obtained. Generally, the traditional Kalman filter has some shortcomings, such as inaccurate model, too much noise, and it is difficult to achieve the optimal estimation, therefore, the application of Kalman filter in spot centroid tracking is optimized. Firstly, the process noise is updated in real time to correct the direction of acceleration accurately and reduce the uncontrollability of process noise by introducing the factor l; Secondly, combined with Wiener filter, the observation value is optimized to minimize the influence of observation noise; Thirdly, starting from the Kalman filter equation, the actual value of the previous moment is connected with the optimal estimated value by weighted addition based on the “Identity of A‐OE” operator, so as to improve the prediction accuracy of the current time. Finally, the EF‐BP neural network is introduced on the basis of the “Identity of A‐OE” operator, and a stable training system is used to optimize the weight repeatedly, so that the error can reach the expected value. The results show that the error of the observation value is reduced by 8.2503%, the error of the optimal filter estimation value is reduced to 0.3490, and the error reduction range is 6.7662. The centroid tracking accuracy of the ablated spot image is improved obviously.
Neurologic Complications due to Severe Micronutrient Deficiencies in an American Adolescent
Authors: Lyles John L. , Hellmann Jennifer A. , Oliveira Stephanie B. 
Published: September 2020

AbstractMicronutrient deficiencies are a major global health problem but are less common in developed nations. If left unidentified and untreated, micronutrient deficiencies can lead to serious, sometimes irreversible, sequelae such as with vitamin A deficiency and vision loss. Providers should recognize these issues not only in chronically ill and hospitalized patients but in those with non–illness‐related malnutrition due to parent/child‐selected restricted diets. Herein, we present a case of unrecognized chronic, severe, malnutrition due to severe behavioral food selectivity with associated neurologic deficits due to hypovitaminosis (vitamins A and B2). With adequate enteral nutrition and vitamin repletion, our patient's neurologic deficits have partially recovered.
An inorganic cross‐linked quadruple shape memory hydrogel with high mechanical performance
Authors: Yin Yan‐Yu , Li Xin , Hu Zai‐Yin , Wang Ru 
Published: September 2020

AbstractShape memory hydrogels (SMHs) have been the subject of great interest in recent years. However, there were few reports on the simultaneous multiple shape memory and high mechanical performance. Therefore, a novel nanocomposite (NC) hydrogel poly (acrylic acid)/Chitosan/ Laponite (PAA/CS/Laponite) was developed by using Laponite as physical cross‐linker. In order to achieve three temporary shapes, the PAA/CS/Laponite was soaked in iron chloride hexahydrate (FeCl3), sodium hydroxide (NaCl) and sodium hydroxide (NaOH) respectively to (a) form metal coordination; (b) gain the chains entanglement of chitosan; (c) get the microcrystalline structure of chitosan. The maximum shape fixity ratio of PAA/CS/Laponite can reach 100% in 1 minute and it can be restored its original shape within 5 minutes. Moreover, PAA/CS/Laponite showed excellent mechanical performance. The maximum tensile and compressive strengths were 0.73 MPa and 13.1 MPa. By comparison with PAA/CS obtained from our previous work, the tensile strength, elongation at break and compressive strength increased by 2.21 times, 1.46 times, and 3.26 times respectively. Scanning electron microscopy (SEM) showed that the obtained sample has uniform honeycomb network structures which can effectively explain why the gel has strong mechanical performance. These characteristics make PAA/CS/Laponite have huge application potential in reality.
Theoretical insights into the mechanism of rhodium‐catalyzed, PIII‐directed regioselective CH arylation of indole with anhydride
Authors: Wang Youjia , Shi Yao , Shao Jiaxuan , Deng Chao 
Published: September 2020

AbstractDensity functional theory calculations were performed to study the reaction mechanism of Rh(I)‐catalyzed, P(III)‐directed regioselective CH arylation of indole with anhydride through decarbonylative cross‐coupling. This mechanism involves four major steps: CH activation, oxidative addition, decarbonylation, and reductive elimination. Through this theoretic study, we find that the CH bond activation was accomplished by the hydrogen carbonate (−HCO3)‐assisted concerted metalation‐deprotonation (CMD) process, not through the oxidative addition of Rh(I)‐catalyst. Meanwhile, our calculation results indicate that the regioselectivity of CH bond arylation of indole with anhydride can be attributed to the relative stability of the CMD transition states in the CH bond activation process. Moreover, in the CH activation step, the base (−HCO3) is not coordinated with the Rh center.
An entropy‐based approach to detect and localize intraoperative bleeding during minimally invasive surgery
Authors: Rahbar Mostafa Daneshgar , Reisner Luke , Ying Hao , Pandya Abhilash 
Published: September 2020

AbstractBackgroundDuring minimally invasive surgery (either robotic or traditional laparoscopic), vascular injuries may occur because of inadvertent surgical tool movements or actions. These vascular injuries can lead to arterial or venous bleeding with varying degrees of severity that may be life‐threatening.Materials and MethodsGiven that a bloody spot is characterized by homogenous and uniform texture, our algorithm automatically scans the entire surgical video frame‐ by‐ frame using a local entropy filter to segment each image into different regions sequence. By comparing changes in entropy in the frames sequences, the algorithm detects the moment of bleeding occurrence and its pixel location. We preliminarily tested the algorithm using ten minimally invasive‐surgery videos., each of which contains one surgical‐tool‐induced bleeding.ResultsOur results show that the algorithm can detect bleeding within 0.635 s, on average, after their occurrences and locate the bleeding sources within, on average, 2.5% of discrepancy in pixels from their origins.ConclusionIn this study, we present a novel and promising local‐entropy‐based image processing algorithm that detects spurts of blood and locate their source in real‐time.