bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vers un capitalisme d’intérêt collectif
Authors: Ferone Creuzet Geneviève , Seghers Virginie 
Published: January 2020

C’est dans ce numéro que reprend la série consacrée au rôle des entreprises dans la fabrique du bien commun, ouverte à l’automne 2018 (n° 426), puis prolongée dans les numéros 427, 429 et 431 de la revue Futuribles . Car, comme le montre cet article de Geneviève Ferone Creuzet et Virginie Seghers, le sujet est loin d’être épuisé et l’avènement d’un capitalisme d’intérêt collectif n’en est qu’à ses débuts. Outre la responsabilité sociale des entreprises, qui a permis d’intégrer un certain nombre de principes pour contrebalancer les logiques de court terme ou strictement financières, se développent désormais de nouvelles formes d’entreprises, mieux définies et encadrées juridiquement, visant à intégrer des missions et objectifs de contribution au bien commun dans leurs statuts. Les auteurs, qui ont activement participé au développement de ces nouvelles formes d’entreprises en France, montrent ici comment ont émergé leurs statuts spécifiques et en quoi ils consistent. Inspirées des évolutions survenues en particulier aux États-Unis ces 10 dernières années, des « entreprises à mission » et des « fondations actionnaires » se développent ainsi, notamment, en France, permettant aux entreprises de concilier des objectifs de rentabilité économique avec le souci de l’utilité collective. L’adoption de la loi PACTE (Plan d’action pour la croissance et la transformation des entreprises) au printemps 2019 témoigne de l’intérêt suscité par ces changements de modèle chez les décideurs politiques : un signe encourageant donnant à penser que les nombreux défis de ce siècle peuvent être affrontés par toutes les parties prenantes à leur échelle — pouvoirs publics, citoyens et désormais acteurs économiques, quelle que soit leur envergure… S.D.
Le système de crédit social chinois
Authors: Dubois de Prisque Emmanuel 
Published: January 2020

Dans nos sociétés modernes, de plus en plus connectées et en interaction permanente, la propension à tout noter et tout évaluer va croissant, qu’il s’agisse d’apprécier un échange téléphonique, de noter un service de livraison ou un rendez-vous médical, de donner son avis sur une photo, un article, etc. : l’individu / consommateur / citoyen est régulièrement sollicité pour exprimer son avis. Mais au-delà de ces sollicitations individuelles, déjà discutables, on voit se développer aussi des dispositifs institutionnalisés de contrôle, basés sur des systèmes de notation, à l’instar de celui mis en place en Chine à la fin des années 1990, qui fait l’objet d’un renforcement particulier depuis une dizaine d’années. Big Brother serait-il passé de la fiction à la réalité comme le craignent de nombreux commentateurs occidentaux du système de crédit social (SCS) chinois ? Emmanuel Dubois de Prisque revient ici sur le SCS, montrant comment — inspiré des pratiques occidentales d’évaluation des capacités d’emprunt et de remboursement des acteurs économiques —, ce système s’est insinué dans le quotidien des citoyens chinois. Il souligne quels sont les objectifs des dirigeants chinois en la matière (notamment promouvoir des comportements humains vertueux et la confiance), et en quoi ceux-ci sont tout à fait cohérents avec la longue tradition culturelle et politique du pays. Emmanuel Dubois de Prisque insiste bien sur les risques et limites du SCS pour les droits et libertés de chacun, mais montre aussi les améliorations qu’il a pu susciter en Chine. Il s’interroge enfin sur la possibilité qu’un tel système puisse s’exporter dans les sociétés occidentales, bien que cela lui semble pour l’instant peu vraisemblable compte tenu des exigences qui sont les leurs en termes de libertés. S.D.
Electromyography of the Shoulder: An Analysis of Passive Modes of Exercise
Authors: Dockery Michael L , Wright Thomas W , LaStayo Paul C 
Published: January 2020

ABSTRACT
Passive shoulder motion is standard early rehabilitation in patients undergoing rotator cuff repair. A number of rehabilitation protocols exist to obtain this goal. This article evaluated different rehabilitation protocols using electromyographic analysis of the rotator cuff muscles to determine if the different protocols promote passive motion. Ten healthy volunteers underwent EMG to investigate the relative activity of the rotator cuff muscles during various exercises used postoperatively following shoulder surgery. The exercises tested were continuous passive motion machine (CPM), pulley, pendulum, self-assisted bar raise using the contralateral arm for power, self-assisted internal and external rotation, therapist-assisted elevation in plane of the scapula, and therapist-assisted internal and external rotation. The relative activity of the supraspinatus, infraspinatus, anterior deltoid, and trapezius muscles were measured and expressed as a percentage of maximal activity.
For all muscle groups tested, the pulley exercise showed significantly more activity than the CPM machine. In the supraspinatus muscle, the pulley exercise averaged 1 7.6% of maximal activity and 8.7% for the self-assisted bar raise using contralateral arm power compared with 5.0% for the CPM machine. In general, therapist-assisted exercises and Codman's pendulum exercises showed activity that was not significantly different from the CPM machine. These results indicate that CPM and therapist-assisted passive range of motion, by being more passive, may increase the safety margin for obtaining early passive range of motion without disrupting the rotator cuff repair.
The Use of Controlled-Release Versus Scheduled Oxycodone in the Immediate Postoperative Period Following Total Joint Arthroplasty
Authors: Kerpsack James M , Fankhauser Richard A 
Published: January 2020

abstract
This prospective study examined whether better pain control could be achieved in the first 48 hours after joint arthropiasty with control led-release oxycodone compared to scheduled oxycodone with acetaminophen. In the study group, control led-release oxycodone was administered on the day of surgery and was continued during patients' hospital stay. The study group then was compared to a previous group in which effective pain control was obtained with around-theclock oxycodone with acetaminophen. Findings indicated control led-release oxycodone did not provide better pain control compared to scheduled oxycodone with acetaminophen in the first 48 hours following total joint arthroplasty.
Management of Proximal Femoral Shaft Fractures in Osteopetrosis: A Case Series Using Internal Fixation
Authors: Chhabra Anikar , Westerlund L Erik , Kline Alex J , McLaughlin Robert 
Published: January 2020

abstract
Osteopetrosis is a group of rare sclerosing bone dysplasias. Orthopedic concerns in Osteopetrosis are principally related to the characteristic brittle "marble bone" in which fractures may be easily induced by relatively low-energy mechanisms. Femoral fractures are common in this patient population, and management presents a unique technical challenge. While osteopetrotic bone may be penetrated with a drill bit, the drill bit flutes are immediately filled with bone. This renders the drill ineffective, and generation of significant frictional heat can result in breakage of the drill. This case series describes the long-term management of nine osteopetrotic femoral fractures in three patients. The difficulties encountered in these cases prompted the development of a safe and efficacious technique for intramedullary fixation of these fractures.
Chronic-graft-versus-host-disease-related polymyositis: a 17-months-old child with a rare and late complication of haematopoietic stem cell transplantation.
Authors: Chinello Matteo , Balter Rita , De Bortoli Massimiliano , Vitale Virginia , Zaccaron Ada , Bonetti Elisa , Tonin Paola , Vattemi Gaetano , Guglielmi Valeria , Cesaro Simone 
Published: January 2020

Background: Chronic graft versus host disease (cGVHD) occurs in 20-30% of paediatric patients receiving haemopoietic stem cell transplantation (HSCT). Neuromuscular disorders such as polymyositis are considered a rare and distinctive but non-diagnostic manifestation of cGVHD and, in absence of other characteristic signs and symptoms, biopsy is highly recommended to exclude other causes.
Case report: We report a case of a 17-months-old child affected by hemophagocytic lymphohistiocytosis who underwent a matched unrelated donor haematopoietic stem cell transplantation (HSCT). She developed a severe cGVHD-related polymyositis that was successfully treated with high-dose steroid therapy, rituximab and sirolimus.
Conclusions: This is the first case of cGVHD-related-polymyositis described in a pediatric patient which was successfully treated with rituximab.
THE PROGNOSTIC SIGNIFICANCE OF TET2 SINGLE NUCLEOTIDE POLYMORPHISM IN EGYPTIAN CHRONIC MYELOID LEUKEMIA
Authors: Dammag Enas A , Hamed Nahla A.M. , El Halawani Nabil A , Kassem Heba S , Ayad Mona W 
Published: January 2020

Background: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm. The pathogenesis of CML is based on the oncoprotein termed BCR‐ABL1. TET2 initiates DNA demethylation and is frequently mutated in hematological malignancies including CML.(1) The relation between TET2 acquisition and CML transformation and/or imitinab resistance is needed to be investigated. (2)
Aim: To evaluate Ten Eleven Translocation 2 gene (TET2) single nucleotide polymorphism (SNP) (rs2454206, rs34402524, rs61744960) in chronic myeloid leukemia (CML) in relation to the disease prognostic criteria.
Materials & Method: The study included 84 subjects; 54 CML in chronic phase and 30 healthy subjects as control group matched for age and sex. Routine investigations including CBC, bone marrow aspiration, biochemical investigations and molecular study were performed in CML patients to identify the disease stage. DNA extraction and SNP assay for TET2 gene polymorphism was done using (Thermo-Fisher predesigned SNP, USA) PCR prism 7500.
Results: The mean age was 45.98±15.7 yrs in CML patients and 39.3±6.587 yrs in control group (p>0.05). TET2 SNP rs 34402524 was either heterozygous and homozygous in CML (48%,and 46.2%) but was mainly homozygous among control (80%) group (p=0.012). TET2 SNP rs 2454206 cases within CML (65.4%) and control (63.3%) group had wild patterns (p=0.046). TET2 SNP rs 61744960 showed a homozygous pattern among all groups (CML and control) showing no statistical significance (p=0.528). TET2 SNP in CML cases did not alter the prognostic criteria as no statistical significance was noted (p>0.05) yet, it was significantly related to spleen size in rs 34402524 where homozygous group had huger sizes and higher BCR-ABL1 levels 6 months after starting TKIs (p<0.05).
Conclusions/Recommendation: TET2 SNP is a common in Egyptian chronic myeloid leukemia. TET2 SNP rs 3442524 was associated with huger spleen size and higher BCR-ABL1 levels after 6 months of starting TKIs suggesting disease progression.
The impact of lymph node ratio on overall survival in patients with colorectal cancer
Authors: İmamoğlu Goksen İnanç , Oğuz Arzu , Cimen Sanem , Eren Tülay , Karacin Cengiz , Colak Dilşen , Altşbaş Mustafa , Türker Sema , Yazılıta Doğan 
Published: January 2020

Background:
Lymph node metastasis is a predominant prognostic indicator in colorectal cancer. Number of lymph nodes removed surgically was demonstrated to correlate with staging accuracy and oncological outcomes. However, number of lymph nodes removed depends on uncontrolled variables. Therefore, a more reliable prognostic indicator is needed. Calculation of ratio of positive lymph nodes to total number of removed lymph nodes may be an appealing solution.

Materials and Methods:
We retrospectively analyzed data of 156 Stage III colorectal cancer patients whom underwent surgery between 2008 and 2015. Patients' demographic characteristics, tumor grade, location, vascular-perineural invasion status, number of removed lymph nodes, and ratio of positive lymph nodes to number of removed lymph nodes were recorded. Spearman correlation analysis was used to determine the correlation coefficient while Kaplan–Meier method and Cox proportional hazard regression model were performed for the prediction of survival and multivariate analysis, respectively.

Results:
Number of removed lymph nodes did not correlate with survival, but it was inversely correlated with number of positive lymph nodes. Multivariate analysis showed that ratio of removed positive lymph nodes to the total number of lymph nodes was a significant prognostic factor for survival for a ratio equal or above 0.31 was a poor prognostic indicator (108 months vs. 34 months, hazard ratio: 4.24 [95% confidence interval: 2.15-8.34]; P < 0.019). Tumor characteristics failed to demonstrate any prognostic value.

Conclusions:
This study showed that positive lymph node ratio (PLNR) is an important prognostic factor for Stage III colorectal cancer. Although 0.31 can be taken as threshold for “PLNR,” prospective trials including larger patient groups are needed to validate its role as a prognostic indicator.
Van procedure naar praktijk
Authors: Verwest Femke , Kunseler Eva , Diederen Paul , Faasse Patricia 
Published: January 2020

From procedure to practice – Effectively safeguarding independence at the Netherlands Environmental Assessment Agency.
If the stakes are high, policy researchers can find themselves under strong pressures from politicians or policy makers to compromise on issues like scope of a research project, research methodology, reporting, framing and interpretation of results, and timing of publication. Research organizations experiment with various formal and informal arrangements to cope with such pressures and guard their independence.This article describes six coping strategies that are being explored by the Netherlands Environmental Assessment Agency (PBL). These are: i) taking control in determining the project scope and the research questions; ii) making responsibilities explicit and guarding respective roles; iii) installing a broad based societal project advisory group; iv) having some researchers in a project that interact with stakeholders, while keeping others at a distance; v) having a differentiated communications strategy; vi) being fully transparent as to hypotheses and uncertainties regarding data and models.Safeguarding independence in research through formal rules and provisions is generally insufficient to protect research from undue stakeholder influence. Also changes in labor routines, relationship management and organizational cultures are needed, not only on the researcher side, but on the stakeholder side as well. This calls for dialogue and joint learning processes.
Onafhankelijk onderzoek in het biomedische gebied
Authors: Rosendaal Frits R. 
Published: January 2020

Independent research in biomedicine
The author discusses the practices, problems and pitfalls research in the biomedical field with regard to conflicts of interests. Medicines are not ordinary products: the exclusive right to prescribe lies with the doctor, and because of the potentially life-saving nature of medicines, their use, price and availability is surrounded by emotions, especially when there is only one medicine available for a serious illness. Nonetheless, these products are marketed by companies that have a primarily commercial interest and, on the basis of those interests, engage in pricing and advertising activities. In the research on medicines, there is close cooperation between the pharmaceutical industry and doctor-researchers, whereby independence is at stake due to the large financial interests and reimbursements. This pushes the design, outcome and publication of research in a direction that is favorable to the pharmaceutical industry, but that is not financially the best direction for society, or medically for patients.
Weinig consistent, beperkt zelfkritisch
Authors: Faber Bram , Budding Tjerk 
Published: January 2020

Hardly consistent, nor self-critical: an analysis of conclusions drawn in the accountability process on the national level
The Dutch central government has a long history in its search to meaningfully present policy effects. One of the instruments that was developed to this end is the Policy Conclusion (beleidsconclusie). This part of the annual report, which has been mandatory since 2013, should provide a judgement for every policy article on its results in the year 2017. To what extent has the Policy Conclusion been successful in its aims? And how do various governmental departments give substance to it? For this article, all policy conclusions that were composed for the most recent reporting year were examined. Among others, our analysis shows that departments differ greatly in their interpretation of what the Policy Conclusion should include, such as the usage of sources and the way in which intended results are (re)addressed. In addition, it was found in the Policy Conclusions that a tendency exists to put a strong focus on positive outcomes.
Preoperative Nursing Care to Reduce Anxiety of Parent from Cancer Patient in Paediatric Surgical Ward
Authors: Gandana Ratna Suryani , Waluyanti Fajar Tri 
Published: January 2020

<p><strong>Objective: </strong>Cancer or malignant tumors are one of the most experienced diseases in the world. The therapy to treat cancer requires a comprehensive examination, one of which is by doing a biopsy. Biopsy is a procedure that can cause anxiety in parents of children with cancer. One of the way to reduce anxiety in parents of children with cancer is to do preoperative education. The purpose of study was to determine the effects of preoperative education on anxiety in parents of cancer patients.</p><p><strong>Methods: </strong>This was a case study of preoperative care to reduce anxiety of parents whose child has cancer and will undergo a surgery. The intervention included anticipatory guidance and preoperative education. Anticipatory guidance was given by actively listening to parents and child’s concerns and assist them to learn deep breathing relaxation techniques, and distraction. The preoperative education was given using a flipchart containing information pertaining to the location and time of surgery, preoperative preparation, surgical procedures, and postoperative care.</p><p><strong>Results: </strong>Parents’ anxiety declined from the score of 7 to 3. She also expressed the feeling of relieved. She looked calmer, focused and made eye contact. <strong></strong></p><p><strong>Conclusion: </strong>Patient education along with anticipatory guidance needs to be provided by nurses during preoperative stage to reduce both parents and patients’ anxiety.</p><p class="AbstractContent"><strong>Key</strong><strong> </strong><strong>words:</strong> cancer, anxiety, parents, preoperative education</p>
The Relationship between Nurses’ Caring Behaviors and Patient Characteristics with Adherence to Hemodialysis Therapy Management in End-Stage Renal Disease Patients
Authors: Zahra Khairina , Edison Chiyar 
Published: January 2020

<div><p class="Keywords"><strong>Objective: </strong>Hemodialysis therapy management consists of four main aspects; hemodialysis program, medication, fluid restriction, and diet. One of important factors in patients’ adherence to hemodialysis therapy is the relationship between health care providers and patients. Nurses have a great role in improving patients’ adherence since they have the most acquaintances with patients. The purpose of this study was to identify the association between caring nurses’ behaviors and respondent characteristics with adherence to hemodialysis therapy management in end- stage renal disease patients.<strong> </strong></p><p class="Keywords"><strong>Methods: </strong>This study employed a descriptive quantitative research design with a cross sectional approach. A purposive sample of 97 ESRD patients on hemodialysis were involved in this study. data were collected using questionnaire to identify patients’ characteristics, perception on nurses caring behaviors, and compliance on hemodialysis therapy management. Data were analyzed using univariate and bivariate analyses.</p><p class="Keywords"><strong>Results: </strong>Over half of the patients were adherent to hemodialysis therapy management (50.5%) and perceived that nurses have caring behaviors (54.6%). Age, gender, education, economic and marital status were not associated with patients’ adherence. In addition, nurses caring behaviors were not related with patients’ adherence. In contrast, family support was significantly linked with patients’ adherence (p = 0.033).</p><p class="Keywords"><strong>Conclusion: </strong>Nurses caring behaviors were not related to patients’ adherence but family support was. Nurses need to involve family in nursing care as appropriate to better improve patients’ adherence.<strong> </strong></p><p class="Keywords"><strong>Key words: </strong>end- stage renal disease, nurses’ caring behaviors, patients’ adherence <strong></strong></p></div>
Membrane Interactivity of Non-steroidal Anti-inflammatory Drugs: A Literature Review
Authors: Tsuchiya Hironori , Mizogami Maki 
Published: January 2020

Background: Although the mode of action of non-steroidal anti-inflammatory drugs (NSAIDs) has been exclusively referred to as inhibition of cyclooxygenase, their broad pharmacological and toxicological spectra are not necessarily interpreted by the direct interaction with such enzyme proteins.
Aims: Since NSAIDs have the common amphiphilic structure, they have the possibility of acting on membrane-constituting lipids. In order to gain insights into the additional mechanism of NSAIDs, we reviewed their membrane interactivity to modify the physicochemical properties of membranes.
Methodology: We retrieved scientific articles from PubMed/MEDLINE, Google Scholar and ACS Publications by searching databases from 1990 to 2019. Research papers published in English in the internationally recognized journals and on-line journals were cited with preference to more recent publications. Collected articles were reviewed by title, abstract and text for relevance.
Results: Results of the literature search indicated that NSAIDs structure-specifically cause the in vitro and in vivo interactions with artificial and biological membranes to change membrane fluidity, lipid phase transition and permeability. The features and potencies of their membrane interactivity vary depending on drug concentration, medium pH and membrane lipid composition. In addition to membrane proteins, NSAIDs act on membrane lipids to exhibit the anti-inflammatory and anti-tumor activity by interacting with lipid bilayer membranes at relatively low concentrations to decrease membrane fluidity and thereby affect the enzymatic activity of membrane-associated proteins and to exhibit the gastrointestinal and cardiovascular toxicity by interacting with membranous phospholipids at relatively high concentrations to increase membrane fluidity and thereby impair the membrane-relevant biofunctions. Other diverse effects of NSAIDs may also be related to their membrane interactions.
Conclusion: NSAIDs share the membrane interactivity common to them as one of possible pharmacological and toxicological mechanisms.