bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accuracy and Precision of Three Consumer-Grade Motion Sensors During Overground and Treadmill Walking in People With Parkinson Disease: Cross-Sectional Comparative Study
Authors: Lai Byron , Sasaki Jeffer E , Jeng Brenda , Cederberg Katie L , Bamman Marcas M , Motl Robert W 
Published: January 2020

Background
Wearable motion sensors are gaining popularity for monitoring free-living physical activity among people with Parkinson disease (PD), but more evidence supporting the accuracy and precision of motion sensors for capturing step counts is required in people with PD.

Objective
This study aimed to examine the accuracy and precision of 3 common consumer-grade motion sensors for measuring actual steps taken during prolonged periods of overground and treadmill walking in people with PD.

Methods
A total of 31 ambulatory participants with PD underwent 6-min bouts of overground and treadmill walking at a comfortable speed. Participants wore 3 devices (Garmin Vivosmart 3, Fitbit One, and Fitbit Charge 2 HR), and a single researcher manually counted the actual steps taken. Accuracy and precision were based on absolute and relative metrics, including intraclass correlation coefficients (ICCs) and Bland-Altman plots.

Results
Participants walked 628 steps over ground based on manual counting, and Garmin Vivosmart, Fitbit One, and Fitbit Charge 2 HR devices had absolute (relative) error values of 6 (6/628, 1.0%), 8 (8/628, 1.3%), and 30 (30/628, 4.8%) steps, respectively. ICC values demonstrated excellent agreement between manually counted steps and steps counted by both Garmin Vivosmart (0.97) and Fitbit One (0.98) but poor agreement for Fitbit Charge 2 HR (0.47). The absolute (relative) precision values for Garmin Vivosmart, Fitbit One, and Fitbit Charge 2 HR were 11.1 (11.1/625, 1.8%), 14.7 (14.7/620, 2.4%), and 74.4 (74.4/598, 12.4%) steps, respectively. ICC confidence intervals demonstrated low variability for Garmin Vivosmart (0.96 to 0.99) and Fitbit One (0.93 to 0.99) but high variability for Fitbit Charge 2 HR (–0.57 to 0.74). The Fitbit One device maintained high accuracy and precision values for treadmill walking, but both Garmin Vivosmart and Fitbit Charge 2 HR (the wrist-worn devices) had worse accuracy and precision for treadmill walking.

Conclusions
The waist-worn sensor (Fitbit One) was accurate and precise in measuring steps with overground and treadmill walking. The wrist-worn sensors were accurate and precise only during overground walking. Similar research should inform the application of these devices in clinical research and practice involving patients with PD.
FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF ANTIEPILEPTIC DRUG
Authors: Akhtar Md. Semimul 
Published: January 2020

The objective of the present study was to prepare and evaluate the mouth dissolving tablet of lacosamide using super disintegrants like Guar Gum, and other excipients like microcrystalline cellulose and mannitol in different concentrations by direct compression method. Lacosamide has been shown to be an effective antiepileptic agent appropriate for epilepsy patients. The mouth dissolving tablets were prepared by a single punch machine using a powder blend of super disintegrants and lacosamide. Post-compression parameters like hardness, weight variation, friability, in-vitro dispersion, drug content uniformity, and in-vitro drug release studies were carried out for all formulations. All formulations results were within official limits. Fast disintegration time obtained between 35 sec. and 128 sec, was within the official limit. Different drug release kinetic models were applied for selecting batches for stability studies. These showed that there was no significant change in residual drug content in mouth dissolving tablets. By the in-vitro disintegration, it is concluded that formulation prepared by Guar Gum (10%) showed faster disintegration time than that of MCC. This indicates that the use of super disintegrants increases the release of drug from the formulation. Therefore, it can be concluded that such mouth dissolving tablets are suitable delivery systems for lacosamide.
Peer Review History:
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Received file

Average Peer review marks at initial stage: 3.0/10
Average Peer review marks at publication stage: 7.0/10
Reviewer(s) detail:
Name: Dr. Iman Muhammad Higazy
Affiliation: National Research Center, Egypt
E-mail: imane.higazy@hotmail.com

Name: Dr. Mohamed Salama
Affiliation: Modern University for Technology & Information, Egypt
E-mail: salama47@yahoo.com
Comments of reviewer(s):

Similar Articles:
FAST DISSOLVING DRUG DELIVERY SYSTEMS: FORMULATION, PREPARATION TECHNIQUES AND EVALUATION
FAST DISSOLVING TABLETS: A PROMISING APPROACH FOR DRUG DELIVERY
DEVELOPMENT AND EVALUATION OF FAST DISSOLVING THIN FILMS OF ARIPIPRAZOLE
IN VITRO-IN VIVO BIO-EQUIVALENCE CORRELATION STUDY OF ATENOLOL, AND ITS BRANDS OF IMMEDIATE RELEASE TABLET UNDER BIO-WAIVER CONDITIONS
Authors: EM Ahmed , ME Ibrahim , FF Magbool 
Published: January 2020

The aim of present study is to examine the in-vitro-in-vivo correlation (IVIVC) of immediate release product. Atenolol 100mg and its brands of immediate release dosage forms. Atenolol is clearly classified into BCS class III, and could be evaluated under bio waiver conditions. The in vitro parameters employed were hardness, weight uniformity, friability, disintegration time, absolute drug content, dissolution rate (in 0.1 N Hydrochloric acid, phosphate buffer and acetate buffer at 37ºC), and dissolution efficiencies were also analyzed. The in-vitro dissolution study was performed on the brands, according to FDA,USP dissolution profile in three different PH (1.2),(4.5), and (6.8) at 37ºC, using the USP apparatus II, then f1, f2 were determined for the time intervals of 10, 15, 30, 45 and 60 minutes, and dissolution efficiencies were calculated. MINITAB 14 statistical program used for in vitro-in vivo correlation, level A was done for reference product. A non linear relation was established which is typical for immediate release formulation, of class III.
Peer Review History:
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Received file

Average Peer review marks at initial stage: 3.0/10
Average Peer review marks at publication stage: 7.0/10
Reviewer(s) detail:
Name: Dr. Hayriye Eda Şatana Kara
Affiliation: Gazi University, Turkey
E-mail: eda@gazi.edu.tr

Name: Dr. Nicola Micale
Affiliation: University of Messina, Italy
E-mail: nmicale@unime.it

Comments of reviewer(s):

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FAST DISSOLVING DRUG DELIVERY SYSTEMS: FORMULATION, PREPARATION TECHNIQUES AND EVALUATION
FAST DISSOLVING TABLETS: A PROMISING APPROACH FOR DRUG DELIVERY
DEVELOPMENT AND EVALUATION OF FAST DISSOLVING THIN FILMS OF ARIPIPRAZOLE
TABLET GRANULATION: CURRENT SCENARIO AND RECENT ADVANCES
Diversidade, migrações e inclusão: desafios à gestão e à democracia
Authors: Moll Jaqueline , Barbosa Márcia Carmen Silveira 
Published: January 2020

Os desafios da educação são desafios de toda sociedade. No contexto da própria afirmação democrática e de nossa capacidade de viver juntos está o do aprendizado da diversidade e o do acolhimento de imigrantes. Em um país como o Brasil, que tem nas suas matrizes povos originários renegados, povos trazidos como escravos e imigrantes, há um caminho a ser construído que precisa dialogar com a capacidade de ressignificar o passado e reescrever o presente, para que o futuro – como dizia Paulo Freire – possa ser transformado. A escola pública brasileira tem enfrentado muitos temas, um deles é o da diversidade. Inicialmente, é construir o sentido de pertencimento para/com os sujeitos do campo e também das regiões urbanas, o que inclui crianças, jovens e adultos com sua diversidade de histórias pessoais e coletivas, em sua raça, religião, gênero, opções políticas, ideologias. Não tem sido uma tarefa fácil nem para os professores, nem para as famílias, nem mesmo para os próprios sujeitos da educação. Há um caldo cultural de xenofobia e de outras fobias, que é preciso identificar, compreender e enfrentar. Nos últimos anos, há uma provocação às escolas brasileiras, especialmente as públicas: o tema das novas migrações. Chegam ao país moradores de toda a América Latina, especialmente haitianos, bolivianos, colombianos e venezuelanos. Da América Central vieram os haitianos, da África os congoleses e angolanos, e da Ásia ocidental estão chegando os sírios (ACNUR, Brasil, 2019). Como a escola, a comunidade educativa, o sistema educacional pode se organizar para acolher essa diversidade? Como afirmar a diversidade em um contexto social e político que fomenta a intolerância e aprofunda desigualdades econômicas? Compartilhar experiências de gestão educacional pública que acolham a diferença e as migrações é o objetivo desta entrevista, além de outros temas relevantes para a educação pública. No contexto da Escuela de Verano do Instituto Rosa Sensat de formação de professores, em julho de 2019, Jaqueline Mol, professora titular da UFRGS, professora do PPGEDU/ URI e do PPGEC/UFRGS e Maria Carmen Silveira Barbosa, professora titular da UFRGS, professora no PPGEDU/UFRGS e editora da Revista Infância Latinoamericana realizaram esta entrevista com o professor Miquel Essomba, secretário Municipal de Educação de Barcelona, desde 2015.
CE Article: Central Venous Catheter Infection in Canadian Home Parenteral Nutrition Patients: A 5-Year Multicenter Retrospective Study
Authors: Saqui Olivia , Fernandes G. , Allard J. 
Published: January 2020

Highlights
A lower CVC infection rate suggests an improvement in practice and education. CVC infection remains a complication that often requires significant health care resources. Use of tunneled CVC and patient education on catheter care reduces CVC infection rates.
РЕЦЕНЗИЯ НА КНИГУ «ВИДИМОЕ ОБУЧЕНИЕ: СИНТЕЗ РЕЗУЛЬТАТОВ БОЛЕЕ 50 000 ИССЛЕДОВАНИЙ С ОХВАТОМ БОЛЕЕ 86 МИЛЛИОНОВ ШКОЛЬНИКОВ» / ДЖОН А. С. ХЭТТИ; ПОД РЕД. В. К. ЗАГВОЗДКИНА, Е. А. ХАРМАЕВОЙ. М.: НАЦИОНАЛЬНОЕ ОБРАЗОВАНИЕ, 2017. 496 С. (АНТОЛОГИЯ ОБРАЗОВАНИЯ)
Authors: Pozdeeva Svetlana 
Published: January 2020

..
Study of Physiochemical Properties of Local Wheat Cultivars and Their Effect on White Layer Cake Quality
Authors: Omer Shano Abdulrahman , Amin Saber Dlir 
Published: January 2020

Physiochemical and rheological properties of local wheat cultivars were studied to determine and develop their relationship to baking quality of white layer cake. The investigation carried out via studying four different wheat cultivars (Adana, Sham 6, Tamooz 2, and Slemani 2), and comparing to a locally produced flour (from Sulaimani Cereal Milling Company) as control. According to physical parameters, the highest value were obtained by Slemani 2, and in terms of falling number control also recorded the highest. In regards to chemical composition (such as; Protein, Fat, Ash, and Moisture) the greatest values were reported by (Tamooz 2, Sham 6, Adana, and Slemani 2) respectively. Nevertheless, rheological characteristics for farinograph in terms of (water absorption, developing time, stability, and tolerance mixing index), the highest values were achieved by (Tamooz 2, Adana, Control, and Sham 6), respectively. While for amylograph characteristics the highest values were recorded in Slemani 2, and Control in terms of (pasting temperature, and peak viscosity) respectively. The gluten yield parameters tested for gluten index, and dry gluten in which the results obtained for Control, and Sham 6 were the greatest. For physical characteristics of the white layer cake the Control achieved the highest value for volume index, symmetry index, and specific volume. Finally, the Control and Adana have scored the highest values for sensory evaluation. In general, the best white layer cake quality was obtained from the Control, Adana, and Sham 6, hence the protein quality and quantity have great influence on the end product.
Dificuldades dos enfermeiros no cuidado ao paciente com morte encefálica
Authors: Silva de Souza Matos Veronica , Cardoso Sampaio Maria Imaculada 
Published: January 2020

Compreender quais são as atribuições do enfermeiro na assistência ao paciente com morte encefálica e expor as dificuldades desses profissionais que são indispensáveis nos serviços de saúde. Trata-se de uma revisão integrativa, construída a partir de materiais já publicados, especificamente artigos científicos, entre 2008 e 2018. Foram consultadas as fontes BVS e SCIELO. Logo após a busca, foram identificados 10 artigos relevantes para este estudo. Concluiu-se a importância e a diferença que este profissional proporciona nos casos de paciente com morte encefálica, sendo este profissional que muitas vezes notifica a existência de um paciente com morte encefálica para a organização de procura de órgãos ou central estadual de transplante.
La novela de la Revolución y la novela de la disidencia en la literatura cubana de los años 70
Authors: Chacon Aida 
Published: January 2020

Desde el triunfo de la Revolución cubana y su posterior institucionalización, la literatura de la isla ha estado en constantes tensiones que han pretendido, a lo largo de los años, dibujar los límites del arte y del compromiso ideológico de los artistas. Sin embargo, durante los años 70, las tensiones llegaron a límites no sospechados y las posturas se polarizaron. Ante el panorama cultural de la isla, algunos escritores determinaron que la única manera de defender el arte era sosteniendo su naturaleza crítica y social desechando la función que el Estado demandaba: hacer del arte un instrumento de difusión ideológica.
En esta primera parte del estudio se sientan las bases de la novela de la Revolución y la novela de la disidencia en Cuba y se establece la clasificación que permitirá el posterior estudio de las poéticas que se alejaron del discurso oficial durante aquella época.
Reconceptualizing patient engagement within research contexts through a relational approach
Authors: Hovey Richard 
Published: January 2020

Currently within the Canadian research landscape, inclusion of patients as partners, research ambassadors have become part of the fabric for research funding;"nothing about me without me". My recent personal experiences at pain conferences and from research team meetings as a patient or more precisely, a person living with chronic pain (PLCP), who is also an academic researcher, suggest we need to evolve a philosophy of engagement that serves both the PLCPs as research ambassadors, rather than patent partners. This presentation is intended to open up conversations about the role of patient experience and the interconnections needed to build strong research communities, through a consideration of a whole person care relational model. In order to meaningfully locate and describe the role of the patient within the structure of a scientific research community I turn to Merleau-Ponty who aptly described the two main perspectives from which we research as, “[t]he world and man [human-beings] are accessible through two kinds of investigations, in the first case explanatory [scientific] and in the second case reflective [philosophical]”. Suggesting, that the language and relationships the emerge and nurtured within research communities need a shared understanding derived from a relational approach rather than a business model of efficiency, experts and teams. A relational approach works toward co-creating a sense of belonging and purpose rather than mere inclusion to meet research funding application criteria. The focus of this presentation is to explore how to co-create a relational approach for researchers with people living with chronic pain.
Graphic Medicine as Physician Tool to Understand Their Patient’s Experience of a Medical Condition
Authors: Janisse Tom 
Published: January 2020

BackgroundEngaging patients in their healthcare, listening to their stories, and improving the quality of their experience also depends on physicians understanding their patient’s experiences of a medical condition.Physicians have little time to converse with patients about this in the visit. Graphic Medicine – Comics – pictures and words together in sequence to tell a story – is a way to gain insight into a patient’s experience of what it’s like. MethodsA small, mixed-method study to test the effect on physicians of reading a comic book, “My Degeneration: Parkinson’s Disease.” The 13 participants, including 11 physician-editors (representing 10 disciplines), answered a 7-question pre-survey before receiving and reading the book, and a 10-question post survey. Also, the 12 participants present at the recent Permanente Journal Editorial meeting commented on their experience of reading the book, its attributes, and their recommendations for the comic book as an educational tool for residents and patients. ResultsGreatest Improvements were: “know patients’ wants,” (54%), “know treatments” (37%), “know patients’ needs” (34%) and “know patients’ experience” (30%). 82% recommended the comic book for resident education, and 73% for patients. Comments included: “My patients say:‘Doc, you guys really need to understand what’s going on for me. It’s really hard for me.’” “The things that people do to deal with their condition are remarkable!” “For a patient to have a conversation with his disease, as in the book, is a wonderful idea. “Combining pictures with words has triple the educational value for millennial residents who demand high yield.”
Team Well-being and Resilience Practices in Hospice and Palliative Care
Authors: Komatsu Glen Isamu 
Published: January 2020

High functioning, resilient teams do not happen by chance. Teams, similar to individuals, need to be educated, nurtured and formed over time, by a consistent vision and process. With proper team formation, the compassionate care of patients, families and colleagues can be developed, modeled and reinforced. Self-compassion is another focus to help caregivers cope with the stresses of the work and mitigate against burnout. The primary intervention which will be discussed is a regularly scheduled reflection process, e.g. 30 minutes weekly or 90 minutes monthly, with a pediatric hospice team, an inpatient palliative care team and an outpatient palliative care team. The reflection process incorporates mindful meditation, journaling, listening exercises, individual and group reflection to encourage and practice self-awareness, self-reflection, greater emotional intelligence and leadership skills. Specific tools employed include the Search Inside Yourself © Program, books by various authors, selected music, videos and personal journals. Qualitative feedback from team members, patient, family and colleague satisfaction scores has been positive. Buy-in from all team members, initially, was difficult, but over time, all team members have recognized the value of the process and have incorporated the exercises not only in their work, but in their personal lives and other roles/jobs. Other key success factors are organizational support for time for this process and individual champions to develop and lead the reflective process. The workshop will include a demonstration of exercises used in team reflections with learner participation.
Beyond Resilience and Burnout: The Need for Organizational Change to Promote Humanistic Practice and Teaching in Healthcare
Authors: Rider Elizabeth A , Gilligan Mary Ann , Osterberg Lars , Branch Jr William T. 
Published: January 2020

Rapid changes in healthcare organization and practice environments, increasingly driven by business models and commercial interests, are associated with widespread burnout and dissatisfaction among healthcare professionals and pose barriers to humanistic relationship-centered quality care. Studies show burnout and significant stress currently affect over half of US physicians and nurses. Clinicians’ ability to provide compassionate care is significantly challenged. Most solutions to date have included individual interventions designed to enhance well-being and promote resilience. We examined organizational factors that inhibit or promote humanistic practice by faculty physicians in today’s healthcare environment. In this qualitative study, physician faculty who completed a one-year faculty development program in humanism at eight US academic medical centers provided written answers to two open-ended questions: a) What institutional or specific organizational unit-related factors promote humanism for you and others? b) What institutional or specific organizational unit-related factors inhibit or pose barriers, to humanism for you and others? 74% (68/92) of the physicians participated. The constant comparative method was used to analyze responses. We found that organizational culture was the central theme. Motivators of humanism included leadership supportive of humanistic practice, responsibility to role model humanism, organized activities promoting humanism, and practice structures that facilitate humanism. Factors that inhibited humanism included “top down” organizational culture, non-supportive leadership, time and bureaucratic pressures, and non-facilitative practice structures. Our findings suggest that organizational culture is, at a minimum, equally important as individual interventions. We describe features of organizational culture that reinforce humanistic practice and care in healthcare institutions and offer recommendations for organizational change that support the primacy of humanistic, compassionate, high quality patient care.