bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of brand familiarity, customer brand engagement and self-identification on word-of-mouth
Authors: Acharya Anitha 
Published: May 2020

PurposeThe purpose of this paper is to check for the effects of brand familiarity, customer brand engagement and self-identification on word-of-mouth (WOM) communication.Design/methodology/approachA systematic review of the literature regarding brand familiarity and customer brand engagement CBE) was conducted and data were analyzed using structural equation modeling.FindingsThe results revealed that brand familiarity had a positive impact on CBE; self-identification also had a positive impact on WOM communication.Research limitations/implicationsThe model was tested in the context of service sector; future research may investigate in different context.Practical implicationsThe framework advances insight into customer engagement and service dominant logic, which, despite having been recognized for their significant theoretical fit, have remained largely disparate in the literature.Originality/valueThis study is among the first few attempts to examine the impact of brand familiarity on different dimensions, namely, cognitive, affective and activation dimensions of CBE. This study contributes to a more detailed description of the brand familiarity construct and improves understanding of WOM communication. The study provides implications for practitioners and marketers.
In search of inclusive tourism in the Caribbean: insights from Aruba
Authors: Peterson Ryan R. , DiPietro Robin B. , Harrill Richard 
Published: May 2020

PurposeThe purpose of this paper is to explore the evolution of inclusive tourism in a small-island tourism economy of the Caribbean. Dubbed the “One Happy Island” in the Caribbean, the operationalization and development of direct and indirect channels of inclusive tourism are studied and discussed to foster policy guidance and future studies.Design/methodology/approachBased on an in-depth case study of Aruba, the findings yield significant insights on the unfolding of inclusive tourism within the context of a maturing small-island tourism economy in Aruba. A mix of historical socioeconomic analysis in conjunction with community resident perspectives provides an expanded framing of small-island inclusive tourism development.FindingsIn mature, small-island tourism economies such as Aruba, social and ecological disparities are particularly evident and over an extended period have exceeded direct economic contribution. The case study reveals an Aruban community experiencing significant negative socioecological impacts and subsequent diminishing economic contribution and well-being. Concerns about environmental pollution and destruction, the loss of quality of life and income equality, in addition to over construction and crowding, indicate a growing animosity toward tourism and further tourism growth.Research limitations/implicationsBased on previous studies, this study provides an extended framing of small-island inclusive tourism, which opens opportunities for further testing and validation across other small-island tourism economies. It provides a conceptual critique of classical tourism growth maxims in small-island developing states.Originality/valueThe paper provides rich historical insights using an in-depth case study approach that extends the concept and evolution of inclusive tourism in mature, small-island tourism destinations, especially in the Caribbean, thus providing a contemporary framing of inclusive tourism.
Mediation role of diversity climate on leadership and job satisfaction in the Ghanaian public sector
Authors: Mickson Michael K. , Anlesinya Alex , Malcalm Ebenezer 
Published: May 2020

PurposeThis study examines the mediation role of diversity climate in the relationship between transformational leadership, transactional leadership and job satisfaction from the two-factor perspectives of intrinsic and extrinsic job satisfactions among local government servants in Ghana.Design/methodology/approachThe study uses cross-sectional data from 322 employees in local government service of Ghana in the Greater Accra Region using purposive and stratified sampling methods. Bootstrapping method of mediation estimated using structural equation modelling is employed to test the hypothesized relationships.FindingsThe results find a differential effect of leadership behaviours on intrinsic and extrinsic job satisfaction, where transformation and transactional leadership relate positively to intrinsic and extrinsic job satisfaction respectively. Furthermore, the empirical findings reveal that diversity climate has mediated the relationship between transformational leadership and intrinsic job satisfaction, implying that diversity climate is an important process through which transformational leadership behaviours can elicit intrinsic job satisfaction among local government servants. Surprisingly, however, diversity climate does not serve as an important transmission mechanism in the relationship between transactional leadership and extrinsic job satisfaction.Practical implicationsThis means that public sector leaders or managers can improve intrinsic job satisfaction among local government servants and by extension public sector employees by creating an ideal climate for diversity by transforming the work environment through leadership, specifically, transformational leadership behaviours.Originality/valueAlthough studies abound on the link between leadership behaviours (transformational and transactional) and job satisfaction, the mediating effect of diversity climate as a mechanism in this relationship is very scarce and rare to find. Hence, our study has made original contributions to theory and practice by highlighting the role of diversity climate in converting leadership behaviours, specifically; transformational leadership into creating intrinsically satisfied workers in the public sector.
Intellectual property rights and the upgrading of the global value chain status
Authors: Yang Gaoju , Zhang Yilu , Yu Xiao 
Published: May 2020

AbstractThe present paper explores how intellectual property rights (IPR) protection affects an economy’s status in global value chains (GVC) by introducing IPR protection into the sequential production model. We find that a suitable IPR protection system that matches the phase of economic and technological development a country has reached is the key for developing countries to upgrade their status in GVC, which are dominated by multinational firms from developed countries. Empirical analysis with multinational panel data for 55 countries from 2005 to 2015 provides evidence in support of the predictions of this model, although the GVC‐enhancing effects of IPR protection are heterogeneous for developing and developed countries. The empirical conclusions are robust after using the instrumental variable method and controlling for endogeneity.
Organizational synthesis in transboundary crises: Three principles for managing centralization and coordination in the corona virus crisis response
Authors: Moorkamp Matthijs , Torenvlied René , Kramer Eric‐Hans 
Published: May 2020

AbstractBoin (2019) argues that in transboundary crisis management it is almost impossible to achieve centralization and coordination. This article identifies three principles through which actors in a transboundary crisis can balance centralization with autonomy while shaping coordination along the way. We reanalysed three transboundary cases: the Dutch military mission in Afghanistan, the downing of MH17 and hurricane Irma striking Sint‐Maarten. The principles we found are as follows: (a) reformulating key strategic priorities, (b) flexible adaptation of crisis management protocols and (c) the emergence of multifunctional units. With these three principles, we reflect on challenges in the Dutch crisis response to the corona outbreak and propose improvements for progressing current crisis management efforts.
Defending British Farming Standards in Post‐Brexit Trade Negotiations
Authors: Wilkinson Derrick 
Published: May 2020

SummaryAfter 47 years of membership, the UK has left the EU, and plans to quickly negotiate new trade agreements with the EU, US, Australia, New Zealand and others. This unique challenge has caused legitimate concerns about the UK opening its market to agri‐food products produced to lower standards. Consumers are concerned about the possible loss of valued assurances about how their food is produced, and producers are concerned about losing domestic market share to cheaper imports. Demands by farming leaders and others for legally binding assurances from the government that they will ban imports of foods produced in ways not allowed in the UK, are unrealistic. If British farmers want to defend their high production standards in the impending trade negotiations, they need to up their game, understand the legal constraints within which UK trade policy will develop, and find new and creative solutions. Equally, a great start for the UK's new trade policy would be for the UK government to provide the leadership needed to better integrate the public's new environmental and animal welfare priorities with the WTO rules. This could also be an area of trade policy that the UK and EU might work together closely to advance.
Biochemical analysis and pathogenicity of entomopathogenic fungi to Diaphorina citri Kuwayama (Hemiptera: Liviidae)
Authors: Naeem Afifa , Freed Shoaib , Akmal Muhammad 
Published: May 2020

AbstractAsiatic citrus psylla, Diaphorina citri, Kuwayama (Hemiptera: Liviidae) is an economic pest of citrus groves and a vector of the bacterium, Candidatus Liberibacter spp., one of the causative agents of citrus greening. In order to estimate the infectivity of six different isolates of Beauveria bassiana, Metarhizium anisopliae and Isaria fumosorosea, fungal bioassay was performed on the adults of D. citri. Adults of D. citri were treated individually with 1 × 105, 1 × 106, 1 × 107, 1 × 108, 2 × 108 spores/mL fungal concentrations by the immersion method. Subsequent to fungal bioassay, treated D. citri were used to determine the levels of esterase and glutathione S‐transferases (GST) enzymes over a period of 3–7 days. The mortality results suggest that I. fumosorosea isolates (If‐02) caused 82.2% mortality on the seventh day of treatment. However, B. bassiana isolate (Bb‐08) with lowest LC50 (1.4 × 107 spores/mL) proved to be highest potential isolate against D. citri. Biochemical determination of esterase and GST activity assay showed significant differences in activities after infection of fungi. Significantly high activity of esterase was observed by Bb‐01 (27.0 unit per mg protein) on the seventh day, while Ma‐11.1 and If‐2.3 (16.9 and 36.3 unit per mg protein) on the third day post treatment. However, maximum GST's activity was showen by isolates Bb‐08,Ma‐M2 and If‐2.3 (37.6, 1.40 and 10.9 unit per mg protein) on the third day. The current investigation will help to explore the relations between the insect defense system and entomopathogenic fungi. Moreover, the determination of enzymatic activities will be useful for selecting the most pathogenic isolates.
Enhancing astaxanthin accumulation in Xanthophyllomyces dendrorhous by a phytohormone: metabolomic and gene expression profiles
Authors: Pan Xueshan , Wang Baobei , Duan Ran , Jia Jing , Li Jun , Xiong Weide , Ling Xueping , Chen Cuixue , Huang Xiaohong , Zhang Guoliang , Lu Yinghua 
Published: May 2020

SummaryXanthophyllomyces dendrorhous is a promising source of natural astaxanthin due to its ability to accumulate high amounts of astaxanthin. This study showed that 6‐benzylaminopurine (6‐BAP) is an effective substrate that enhances cell biomass and astaxanthin accumulation in X. dendrorhous. In the current study, the biomass and astaxanthin content in X. dendrorhous were determined to be improved by 21.98% and 24.20%, respectively, induced by 6‐BAP treatments. To further understand the metabolic responses of X. dendrorhous to 6‐BAP, time‐course metabolomics and gene expression levels of X. dendrorhous cultures with and without 6‐BAP feeding were investigated. Metabolome analysis revealed that 6‐BAP facilitated glucose consumption, promoted the glycolysis, suppressed the TCA cycle, drove carbon flux of acetyl‐CoA into fatty acid and mevalonate biosynthesis, and finally facilitated the formation of astaxanthin. ROS analysis suggested that the antioxidant mechanism in X. dendrorhous can be induced by 6‐BAP. Additionally, the process of 6‐BAP significantly upregulated the expression of six key genes involved in pathways related to astaxanthin biosynthesis. This research demonstrates the metabolomic mechanism of phytohormone stimulation of astaxanthin production iNn X. dendrorhous and presents a new strategy to improve astaxanthin production to prevent the dilemma of choosing between accumulation of astaxanthin and cell biomass.
Cross‐cultural adaptation and validation of the Gait, Arms, Legs, Spine locomotor screening test for detecting musculoskeletal disorders in Mexican adults
Authors: Moreno‐Torres Luis Antonio , Ventura‐Alfaro Carmelita Elizabeth , Aceves‐Ávila Francisco Javier 
Published: May 2020

AbstractAimDeveloped in the United Kingdom, the Gait, Arms, Legs and Spine (GALS) sensitive screening test enables doctors to examine joints and positions at rest and during motion. Therefore, patients with an early diagnosis for musculoskeletal (MSK) disorders, can enjoy a better quality of life than those diagnosed at a later stage. The objective was to adapt and validate a Mexican‐Spanish version of the GALS measurement instrument for MSK disorders in Mexican adults.Materials and methodsWe conducted a cross‐sectional diagnostic test study among 18‐ 60‐year‐old adults in a hospital in the city of Guadalajara, Mexico. Based on international guidelines, we divided our work into 2 phases: first, we developed and adapted a cross‐cultural, Mexican‐Spanish version of the GALS; second, we validated the instrument as a diagnostic test among Mexican patients.ResultsThe adapted version yielded the following scores as a measurement instrument: 0.92 under Cronbach's alpha, 0.695 (95% CI, 0.592‐0.797) in the kappa index, 98.2% (95% CI, 90.3%‐100%) in sensitivity, 80.6% (95% CI, 72.9%‐86.9%) in specificity, and 5.06 for positive likelihood ratio. It also covered an area of 0.89 (95% CI, 0.85‐0.93) under the receiver operating characteristic curve.ConclusionsThe GALS diagnostic test proved valid for detecting MSK disorders among Mexican adults. It can be used by specialized physicians, family doctors, general practitioners and even physicians in training.
Effect of ethanol on Munc13‐1 C1 in Membrane: A Molecular Dynamics Simulation Study
Authors: You Youngki , Das Joydip 
Published: May 2020

BackgroundEtOH has a significant effect on synaptic plasticity. Munc13‐1 is an essential presynaptic active zone protein involved in priming the synaptic vesicle and releasing neurotransmitter in the brain. It is a peripheral membrane protein and binds to the activator, diacylglycerol (DAG)/phorbol ester at its membrane‐targeting C1 domain. Our previous studies identified Glu‐582 of C1 domain as the alcohol‐binding residue (Das, J. et al, J. Neurochem., 126, 715‐726, 2013).MethodsHere, we describe a 250 ns molecular dynamics (MD) simulation study on the interaction of EtOH and the activator‐bound Munc13‐1 C1 in the presence of varying concentrations of phosphatidylserine (PS).ResultsIn this study, Munc13‐1 C1 shows higher conformational stability in EtOH than in water. It forms fewer hydrogen bonds with phorbol 13‐acetate in the presence of EtOH than in water. EtOH also affected the interaction between the protein and the membrane and between the activator and the membrane. Similar studies in a E582A mutant suggest that these effects of EtOH are mostly mediated through Glu‐582.ConclusionsEtOH forms hydrogen bonds with Glu‐582. While occupancy of the EtOH molecules at the vicinity (4Å) of Glu‐582 is 34.4%, the occupancy in the E582A mutant is 26.5% of the simulation time. In addition, the amount of PS in the membrane influences the conformational stability of the C1 domain and interactions in the ternary complex. This study is important in providing the structural basis of EtOH's effects on synaptic plasticity.
Adolescent alcohol use disrupts functional neurodevelopment in sensation seeking girls
Authors: Zhao Qingyu , Sullivan Edith V. , Műller‐Oehring Eva M. , Honnorat Nicolas , Adeli Ehsan , Podhajsky Simon , Baker Fiona C. , Colrain Ian M. , Prouty Devin , Tapert Susan F. , Brown Sandra A. , Meloy Mary J. , Brumback Ty , Nagel Bonnie J. , Morales Angelica M. , Clark Duncan B. , Luna Beatriz , De Bellis Michael D. , Voyvodic James T. , Nooner Kate B. , Pfefferbaum Adolf , Pohl Kilian M. 
Published: May 2020

AbstractExogenous causes, such as alcohol use, and endogenous factors, such as temperament and sex, can modulate developmental trajectories of adolescent neurofunctional maturation. We examined how these factors affect sexual dimorphism in brain functional networks in youth drinking below diagnostic threshold for alcohol use disorder (AUD). Based on the 3‐year, annually acquired, longitudinal resting‐state functional magnetic resonance imaging (MRI) data of 526 adolescents (12–21 years at baseline) from the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) cohort, developmental trajectories of 23 intrinsic functional networks (IFNs) were analyzed for (1) sexual dimorphism in 259 participants who were no‐to‐low drinkers throughout this period; (2) sex‐alcohol interactions in two age‐ and sex‐matched NCANDA subgroups (N = 76 each), half no‐to‐low, and half moderate‐to‐heavy drinkers; and (3) moderating effects of gender‐specific alcohol dose effects and a multifactorial impulsivity measure on IFN connectivity in all NCANDA participants. Results showed that sex differences in no‐to‐low drinkers diminished with age in the inferior‐occipital network, yet girls had weaker within‐network connectivity than boys in six other networks. Effects of adolescent alcohol use were more pronounced in girls than boys in three IFNs. In particular, girls showed greater within‐network connectivity in two motor networks with more alcohol consumption, and these effects were mediated by sensation‐seeking only in girls. Our results implied that drinking might attenuate the naturally diminishing sexual differences by disrupting the maturation of network efficiency more severely in girls. The sex‐alcohol‐dose effect might explain why women are at higher risk of alcohol‐related health and psychosocial consequences than men.
The experience and outcomes of a specialised preterm birth clinic in New Zealand
Authors: Dawes Lisa , Restall Antonia , de Sousa Joana , Pole James Richard , Waugh Jason , Groom Katie 
Published: May 2020

BackgroundA greater understanding of the risk factors for spontaneous preterm birth and the importance of risk stratification to guide interventions has led to the introduction of preterm birth prevention clinics.AimTo evaluate the experience and outcomes of the first specialised preterm birth clinic in New Zealand.Materials and methodsThis observational study reviewed pregnancies cared for in a preterm birth clinic from 2013 to 2018. Cases were identified and data collected from a maternity database and electronic medical records. Analysis was by referral type.ResultsA total of 423 cases were included; 309 elective and 22 acute referrals in pregnancy, and 92 consultations outside pregnancy. For those referred electively in pregnancy, 138/309 (44.7%) fulfilled multiple referral criteria, and 57/309 (18.4%) had ≥2 previous spontaneous preterm births or second trimester losses. Excluding five pregnancies with first trimester miscarriage, 77/304 (25.3%) were managed with a history‐indicated cerclage (11 placed pre‐conception) and 217/304 (71.4%) had cervical surveillance as primary management, of which 133 (61.3%) did not require treatment. The remaining had treatment for a short cervix; 37 (17.0%) received an ultrasound‐indicated cerclage only, 21 (9.7%) vaginal progesterone only and 26 (12.0%) both. Five women (1.6%) had a second trimester loss at 13+0–19+6 and 58/297 (19.5%) had a spontaneous preterm birth at 20+0–36+6 weeks. The ‘take home baby’ rate was 95.4%.ConclusionsPregnancy outcomes were similar to those reported by other preterm birth prevention clinics. The majority of women who received cervical surveillance as primary management were able to avoid additional treatment.
Metabolic shift favoring C18:0 ceramide accumulation in obese asthma
Authors: Choi Youngwoo , Kim Minji , Kim Su Jung , Yoo Hyun‐Ju , Kim Seung‐Hyun , Park Hae‐Sim 
Published: May 2020

AbstractBackgroundObesity associated with various complications has increased worldwide. Body weight gain alters lipid metabolites (especially sphingolipids) contributing to obesity‐induced inflammation. However, the significance of the metabolites in the development of obese asthma is not yet clear.MethodsThe serum levels of sphingolipids were measured using liquid chromatography‐tandem mass spectrometry in obese controls (n = 7) and patients with asthma: the obese group (BMI > 25 kg/m2, n = 13) vs the nonobese (n = 28) group. To examine the relationship between metabolic changes in sphingolipids and macrophage polarization, public microarray data were analyzed. In addition, the alteration in sphingolipid metabolism was investigated in wild‐type BALB/c mice fed a high‐fat diet.ResultsThe obese asthma had higher levels of serum C18:0 and C20:0 ceramides than the nonobese asthma group (P = .028 and P = .040, respectively). The value of the serum C18:0 ceramide (184.3 ng/mL) for discriminating the obese asthma from the nonobese asthma group showed 53.9% sensitivity and 85.7% specificity (AUC = 0.721, P = .024). The microarray data showed significantly increased ceramide synthesis and metabolic shift to ceramide accumulation during M1 macrophage polarization in humans. Increased airway hyperresponsiveness, M1 macrophage polarization, and C18:0 ceramide levels were noted in obese mice, but not in nonobese mice. Increased expression of ceramide synthase (CerS) 1 and CerS6 (not CerS2) was noted in lung tissues of obese mice.ConclusionAlteration in sphingolipid metabolism favoring ceramide accumulation (especially long‐chain ceramides) may contribute to developing obese asthma.