bluuebunny/crossref_metadata_2025_split huggingface dataset:
Side Effects of Intravenous Patient-Controlled Analgesia with Remifentanil Compared with Intermittent Epidural Bolus for Labour Analgesia – A Randomized Controlled Trial
Authors: Karadjova Dafina , Shosholcheva Mirjana , Ivanov Еmilija , Sivevski Аtanas , Kjaev Ivo , Kartalov Adrijan , Kuzmanovska Biljana , Spasova Rosa , Kocovski Goran , Aleksiovska-Papestiev Irena 
Published: February 2020

Abstract

Introduction: Epidural analgesia is considered a gold standard in obstetric anaesthesia and analgesia. However, in situation when it is contraindicated, unwanted by the patient or simply unavailable, remifentanil can be an excellent alternative. The goal of our study is to analyse the side effects of intravenous patient-controlled analgesia (IV PCA) with remifentanil compared with epidural analgesia during delivery.

Material and methods: This study included 155 pregnant women in term for birth, divided into 2 groups: a remifentanil group (RG), and an epidural group (EG). Patients in the RG received intravenous PCA with remifentanil, while patients in the ЕG received epidural analgesia with programmed intermittent bolus dosing. Our primary outcome was maternal safety; the secondary outcome was neonatal safety.

Results: The results present a significantly lower SaO2 value of the parturients in the RG (96.95 ± 1.4 vs 98.22 ± 0.6), and a significantly higher respiratory rate per minute in the EG at all time points after the onset of analgesia (20.85 ± 1.4 vs 18.67 ± 0.9). There was more frequent sedation, nausea and vomiting in the RG, while in the EG there was a more elevated temperature, itching and irregularities in the CTG record. Regarding the newborn, there was no significant difference between the two groups in the Apgar scores, pH, pCO2, pO2, and bicarbonate, while there was a significantly lower value of the base excess in the RG group.

Conclusion: PCA with remifentanil is safe for the mother, foetus and the newborn, with minimal side effects. Continuous respiratory monitoring, oxygen supply and following of all consensus recommendations are mandatory.
Blue Growth Potential in South Baltic Sea Region
Authors: Philipp Robert , Prause Gunnar , Meyer Christopher 
Published: February 2020

Abstract
The Baltic Sea Region (BSR) stands for a flagship maritime region in Europe with dominating SME sector. Nevertheless, compared with other European regions, the cooperation and promotion activities of companies that belong to the Blue Economy in South Baltic Sea Region (SBSR) are not sufficient. As a response to this, the EU-project INTERMARE South Baltic aims to support the maritime economy in the SBSR by the creation of a network of companies and stakeholders.
In line with the project, this study aims to analyse the future potential of the maritime economy and to identify trends that impact the sustainable development of the blue sector in SBSR. Based on primary data from a SBSR wide survey, descriptive statistical analysis is applied and Compound Annual Growth Rate is used as an indicator. The findings reveal need for actions regarding the sub-sectors Transport, Offshore oil & gas, Aquaculture, Fishery, Mineral resources and Biotechnology.
Utilización de las zonas de entrada seguras para el abordaje de lesiones intrínsecas de tronco cerebral en adultos
Authors: Rabadán Alejandra T. 
Published: February 2020

Introducción:
Las “zonas de entrada seguras” (ZES) al tronco cerebral describen accesos destinados a preservar estructuras críticas. La mayoría de las publicaciones son descripciones anatómicas; existiendo pocas sobre su aplicación. En este escenario, nuestro trabajo puede sumar información para el manejo quirúrgico en casos seleccionados.

Material y Métodos:
De una serie de 13 pacientes, se presentan 9 que no eran candidatos para biopsia estereotáctica y recibieron microcirugía. Las localizaciones fueron: mesencéfalo (3), tectum (1), protuberancia (2) y bulbo (3). Cinco pacientes tuvieron KPS ≥70; y 4, KPS <70. Diferentes ZES fueron utilizadas según la topografía lesional. El grado de resección se basó en la biopsia intraoperatoria y el monitoreo neurofisiológico.

Resultados:
Los hallazgos patológicos fueron: astrocitoma pilocítico (1), glioma de bajo grado (1), hemangioblastoma (1), subependimoma (1), disgerminoma (1), y lesiones pseudotumorales (3 cavernomas y 1 pseudotumor inflamatorio). El grado de resección fue completo (4), subtotal (3), y biopsia fue considerada suficiente en (2). Un paciente falleció en el postoperatorio.

Discusión:
Las lesiones del tronco cerebral son infrecuentes en adultos. Las controversias surgen cuando se balancean los beneficios de obtener diagnóstico histopatológico y los riesgos potenciales de procedimientos invasivos. La amplia variedad de hallazgos en esta localización exige una precisa definición histopatológica, que no solamente determinará la terapéutica adecuada, sino que advierte sobre las consecuencias potencialmente catastróficas de los tratamientos empíricos. Las ZES ofrecen un acceso posible y seguro, aunque es más realista considerarlas como áreas para abordar lesiones intrínsecas con baja morbilidad más que como zonas completamente seguras.
Pontocerebellar hypoplasia: clinical case and literature review
Authors: Anužis L. , Buivydas E. , Petrova D. , Šukys M. , Gleiznienė R. 
Published: February 2020

Pontocerebellar hypoplasia (PCH) is a group of rare neurodegenerative disorders which start in the intrauterine period and are inherited by autosomal recessive way. Structural changes caused by the mutation include cerebellar hypoplasia or atrophy, microcephalus, and hypoplasia of ventral pons. Clinical signs and symptoms are present in neonatal period or infancy. Progressive microcephalus, sucking and swallowing disorders, jitteriness, generalized clonus, insufficient development of voluntary movements and cognitive functions, and dystonia can be observed. Magnetic resonance imaging (MRI) along with clinical signs and symptoms is very important in suspecting and diagnosing PCH. Most common MRI features include dragonfly configuration cerebellum in coronal sections, absent or severely reduced in size pontine prominence, various degrees of cerebral cortex atrophy, and delayed myelination. To confirm the diagnosis of PCH2A, genetic analysis is required detecting homozygous missense mutation in the TSEN54 gene. In this article we present a clinical case of a neonate whose diagnosis of PCH2A was suspected by clinical symptoms and MRI features and later confirmed by identifying homozygous missense mutation in the TSEN54 gene.
Corrosion Inhibition Efficiency Of Nicotine Based On Quantum Chemical Study
Authors: Wirayani Yayuk , Ulfa Maria , Yahmin Yahmin 
Published: February 2020

The effect of substituents, electron donor groups (NH2, OH, CH2OH and CH3) and electron withdrawal groups (NO2, COOH, and Cl), to the efficiency of corrosion inhibition of nicotine has been studied using theoretical studies. The effect of substituents toward the efficiency of corrosion inhibition of nicotine based on quantum parameters (EHOMO, ELUMO, Egap, I, Ï‡, dan Î”N). The efficiency of corrosion inhibition based on quantum parameters is NH2 > OH > CH2OH > CH3 > BN > Cl > COOH > NO2. The addition of electron donor group NH2 has the highest inhibitory efficiency of 99.79 %. In contrast, the presence of electron withdrawal group NO2 has the opposite effect.
Pengembangan modul berdasarkan pemecahan masalah polya pada mata kuliah analisis vektor
Authors: Yohanie Dian Devita , Samijo Samijo 
Published: February 2020

Tujuan penelitian ini ingin memgembangkan modul berdasarkan pemecahan masalah Polya pada mata kuliah analisis vektor yang valid. Modul dikembangkan sesuai model 4D Thiaragajan. Modul dinilai oleh validator materi dan bahasa, validator media dan desain pembelajaran, praktisi sesuai dengan angket. Hasil pengembangan modul analisis vektor berdasarkan penilaian validator materi dan bahasa 89,4%, validator media dan desain pembelajaran 98%, validator praktisi 91,35%. Angket respon mahasiswa mendapat nilai 82,7%. Dapat disimpulkan modul berdasarkan pemecahan masalah Polya pada mata kuliah analisis vektor sangat valid dan layak digunakan untuk pembelajaran
Socio-Economic Impact of BP Koirala Institute of Health Sciences on Dharan Town Over the last 20 Years
Authors: Jha N , Sharma KR , Niraula SR , Ghimire A , Yadav DK , Singh SB 
Published: February 2020

Background: Socio-economic changes are constantly occurring in various societies with multiple reasons. Sometimes, the initiation of an educational institution, especially colleges and universities, can have a profound impact on the economy of a town. B. P. Koirala institute of Health sciences (BPKIHS) has been in existence in Dharan since 1993 (a joint project of Government of Nepal and Government of India) and it has been more than its 25 successful years.
Objectives: To examine the role of BPKIHS in changing socio-economic status of Dharan town, and to compare health and economic indicators in various cities like Dharan, Rajbiraj, Birganj, Pokhara and Nepalganj.
Methodology: Both quantitative and qualitative methods were used in this study to assess health and socioeconomic conditions. Information from Dharan was collected through Quantitative methods like Household Survey and Collection of Secondary Data, and Qualitative methods like Focus Group Discussion (FGD) and Interview with Key Informants. Similarly in Rajbiraj, Birganj, Pokhara and Nepalganj; secondary data and interview with key informants were used for gathering information.
Results: A total of 1500 households with 7198 population were surveyed in all 19 wards of Dharan. The rent of houses has increased significantly (p < 0.001) along with the use of items like electricity, radio, television, telephone, motor vehicle, bicycle, computer and gas-stoves compared to 22 years back in Dharan, which is statistically significant. Most (85.6%) of the people of Dharan go to BPKIHS for treatment and about three quarters (73.1%) of the surveyed household reported improvement in health status. More than 70% household reported improvement in socio-economic status of the people of Dharan due to the establishment of the BPKIHS. Comparing records and reports provided by various offices (secondary data) of Dharan, Rajbiraj, Birganj, Pokhara and Nepalganj, remarkable progress is seen in the developmental indicators of Dharan. Likewise key informant interview revealed noteworthy development in Dharan compared to the other four towns, predominantly due to the presence of BPKIHS, while industry/business and tourism were responsible in other towns. The participants of FGDs stated that the existence of the BPKIHS is one among the first three factors responsible for the socio-economic development of Dharan. They also reported that health, education and tourism of the town have been greatly influenced by the presence of the BPKIHS.
Conclusion: BPKIHS has made a great impact in the improvement of health and economic status of the people of Dharan. This survey revealed a positive attitude of the people towards BPKIHS. The future calls for a hand in hand approach with local population and dissemination of up to date and efficient services to further improve socioeconomic and health status of the people of Dharan.
Ocular manifestations in tuberculosis cases with HIV in Nepal
Authors: Bhatta Subash , Shah D. N. , Choudhary Meenu , Thakur Ajit , Pant Nayana 
Published: February 2020

Introduction: TB has seen resurgence associated with HIV. Tuberculosis can affect any ocular tissue. The association of HIV with TB is supposed to increase the incidence and plethora of ocular manifestations in tuberculosis.
Objectives: To study the various ocular manifestations seen in tuberculosis patients with associated HIV infection.
Material and Methods: This hospital based, cross sectional descriptive study was conducted in Tribhuvan University, Teaching Hospital, Maharajgunj, Nepal and Geta Eye Hospital, Kailali from 2010 to 2015. Diagnosed cases of pulmonary and extra pulmonary tuberculosis with HIV co infection were evaluated for ocular manifestations after excluding other opportunistic infections.
Results: Of 70 cases eligible for the study, extra pulmonary tuberculosis was seen in60% of the cases. 5 patients (7.1 %) had ocular manifestations. CD4 counts were <50/mm3 in 3 cases. Ocular involvement was seen in the form of choroidal granulomas, papillitis, cranial nerve palsy, retinal vasculitis and central serous chorioretinopathy.
Conclusion: This study demonstrated that ocular involvement is a frequent finding in cases with tuberculosis and HIV. Ocular findings are more common in cases with lesser CD4 counts. As ocular tuberculosis can be visually devastating, we recommend regular ocular evaluation of all patients with HIV and systemic tuberculosis.
Outcome of cataract surgery in eyes with uveitis
Authors: Singh Kalpana , Shrestha Smita , Manandhar Anu 
Published: February 2020

Purpose: To assess the outcome of cataract surgery in patients with uveitis without the use of prophylactic high dose (> 5-10 mg/day) systemic steroid.
Method: A hospital based prospective study enrolling 64 eyes of 60 patients with uveitis and cataract from May 2013 to April 2014 having intraocular inflammation under control for at least 3 months preoperatively and underwent phacoemulsification with in bag placement of foldable acrylic intraocular lens (IOL).
Results: Twenty six male and 34 female were included with mean age of 47.23 ± 16.85SD (16-85) years. In 43.75 % of eyes the uveitis was idiopathic followed by sarcoiduveitis (18.7%), Herpetic uveitis (15.6%), Tubercular uveitis (6.2%), VKH (4.6%), HLAB 27(4.6%), Behcet’s, endogenous endophthalmitis, Wegener’s granulomatosis and lepromatous uveitis (1.5% each). Anterior chamber cell count was grade 1+ in 33 eyes (51.56%) on 1st post-operative day and in 29 eyes (45.31%) on second follow up. Out of total 11 eyes (17.18%) that developed fibrin, 7 eyes were treated with subconjunctival injection of dexamethasone with half hourly topical steroid drops. Other 4 eyes that developed fibrin responded to half hourly topical steroid. Dose of oralprednisolone increased in 6 patients in early post operative duration. At the final follow up, 50 eyes (92.58% ) had improvement in best corrected visual acuity and cystoidmacular edema (CME) in 5% (n=3) eyes.
Conclusion: Even without the use of preoperative high dose of oral steroid, inflammation was under control with significant improvement in visual acuity 3 months postoperatively.
PORTABLE HEAT METERING SYSTEM DESIGN
Authors: Belous A. N. , Overchenko M. V. , Belous O. E. 
Published: February 2020

In modern construction practice, more than half of buildings in operation require modernization of thermal insulation. However, in order to select an effective insulation system, it is necessary to know the actual thermal and technical characteristics of structures and parameters of the building internal environment. The paper analyzes methods and equipment for evaluation of the thermal performance of outdoor enclosures. The advantages and disadvantages of the main devices recommended by the regulatory documents for field research are shown. According to the data obtained, a heat engineering complex is developed for conducting field studies of heat and humidity of wall structures and microclimate of building premises. Software improvement together with Arduino reader device allow monitoring both at stationary and non-stationary thermal conditions of external enclosures and indoor climate parameters in field conditions.
PRESERVATION OF STOVE HEATING IN A WOODEN HOUSE BUILT IN THE 19–20th CENTURIES IN TOMSK
Authors: Reznichenko T. Yu. 
Published: February 2020

Purpose: The aim of this work is to identify and collect the data on the engineering equipment routinely used for stove heating, which possesses a unique architectural potential determining its typology and preservation. Design/methodology/approach: In addition to a fullscale study, the historical review is given. This study determines the principles the stove arrangement in wooden houses. Research findings: A rapid loss of both historical wooden houses and stove heating systems is shown, which are considered to be the key elements for maintaining a valuable historical environment. A need for determining the causes of the destruction and loss of historical houses is shown. Originality/value: The research includes the not yet published data on historical houses, in particular, at the address 33, October street, Tomsk, Russia, built in the 19– 20th centuries, which is of high architectural potential. Practical implications: The results can be used in preservation of engineering equipment of stove heating in historical wooden houses.
Design of the third-generation neutron spallation target for the CERN’s n_TOF facility
Authors: Esposito Raffaele , Calviani Marco 
Published: February 2020

The neutron Time-Of-Flight (n_TOF) facility at the European Laboratory for Particle Physics (CERN) is a pulsed white-spectrum neutron spallation source producing neutrons for two experimental areas: EAR1, located 185 m downstream of the spallation target, and EAR2, located 20 m above the target. The facility is based on a lead target impacted by a high-intensity 20 GeV/c proton beam. It is designed to study neutron-nucleus interactions for neutron kinetic energies from a few meV to several GeV, with applications in nuclear astrophysics, nuclear technology, and medical research. The facility is undergoing a major upgrade in 2019–2020, which will include the installation of the new third-generation target. The second-generation target consists in a water-cooled lead cylinder, while the new target will be cooled by nitrogen to avoid erosion-corrosion phenomena and contamination of the cooling water with radioactive lead spallation products. The new design will be optimized also for the vertical flight path. The operation of the new spallation target will start in 2021. This paper presents an overview on the evolution of the design and on the related R&D activities (including beam irradiation tests) carried out to ensure the best performance for both experimental areas and avoid the contamination issues of the previous targets.
PRINSIP GOOD CORPORATE GOVERNANCE PADA BANK PERKREDITAN RAKYAT
Authors: Wulandari Siswi 
Published: February 2020

ABSTRAKKajian dalam Penelitian ini adalah penerapan Good Corporate Governance di Bank Perkreditan Rakyat. Good Corporate Governance dibutuhkan sebagai salah satu instrumen pengelolaan manajemen bank yang baik. Dengan pelaksanaan Good Corporate Governance yang efektif maka akan meningkatkan kualitas Sumber Daya Manusia pada BPR. Dengan kualitas Sumber Daya Manusia yang baik maka akan meningkatkan pelayanan bank kepada nasabah. Penelitian ini menggunakan penelitian deskriptif kualitatif. Inti dari Good Corporate Governance adalah moral dan etika yang dibarengi dengan perangkat hukum.Kata Kunci: Bank Perkreditan Rakyat, Good Corporate Governance, sumber daya manusia.
MENINGKATKAN HASIL BELAJAR PJOK TEKNIK DASAR MENGGIRING BOLA MELALUI PENDEKATAN LAPANGAN
Authors: Abidin Zainal 
Published: February 2020

Learning in class IV on PJOK subject matter, Basic Engineering Material, Herding Ball in Soccer Games, mastery of the material is still very low. Of the 20 number of students only 7 students (35%) who achieved the Minimum Completion Criteria (KKM) were set at 6.5 with an average value of 61.5. To overcome the above problems, the steps that need to be implemented are using the approach to field outside the school. In application, the researcher tried on the subject of PJOK about the concept of "Basic Technique of Dribbling Ball". The subjects in this study were 20 students consisting of 13 men and 7 women. To achieve the results in accordance with what the researcher expects, the researchers implement them with II cycles. Each cycle is 2 meetings for 3 months. In the first cycle the average score of students was 68.3 and learning completeness reached 70%, whereas in the second cycle the average score of students was 77 and learning completeness reached 85%. The conclusion of this study is to use the field approach outside the school in the PJOK lesson on material Natural Resources and their use for economic activities can improve learning skills
ANALISA PENGARUH KENAIKAN TEMPERATUR PERMUKAAN SOLAR CELL TERHADAP DAYA OUTPUT
Authors: Pido Rifaldo 
Published: February 2020

Penelitian ini membahas bagaimana pengaruh kenaikan temperatur panel surya terhadap daya output dengan perbandingan solar cell berpendingin air dan tanpa pendingin, pendinginan pada solar cell dengan mengalirkan air pada bagian bawah panel. Besar daya yang diperoleh solar cell tersebut dapat diketahui dengan mengukur arus dan tegangan dengan multimeter. Seksi uji adalah dua buah sel surya dengan kapasitas 50 WP merk monocrystaline yang telah dirancang khusus. Hasil penelitian diperoleh bahwa semakin besar kenaikan temperatur 50,92 °C, maka daya output menurun untuk solar cell tanpa pendingin air 42,51 watt, sedangkan untuk solar cell dengan aliran air daya yang dibangkitkan sebesar 45,36 watt pada temperatur permukaan 34,36 °C, diperoleh pada intensitas matahari yang samaThis study discusses how the effect of rising solar panel temperatures on output power by comparison of water-cooled and non-refrigerated solar cells, cooling the solar cell by flowing water at the bottom of the panel. The power obtained by the solar cell can be determined by measuring the current and voltage with a multimeter. The test section is two specially designed solar cells with a capacity of 50 WP monocrystalline. The results obtained that the greater the increase in temperature of 50.92 ° C, the output power decreases for solar cells without water cooling 42.51 watts, while for solar cells with a flow of water power generated by 45.36 watts at surface temperature 34.36 ° C, obtained at the same sun intensity.
Method of organization of events of neutralization of sources of risks and threats of economic security with use of conceptual model of sources of risks and threats
Authors: Troshin D. V. 
Published: February 2020

The work purpose — systematization and typification of actions of subjects of the Federal risk management system (further — FRMS) on the organization of counteraction to sources (subjects) of risks and threats.System approach, methods of conceptual modeling, scenario modeling, program and target planning are used. For the solution of private tasks it is offered to use imitating modeling, optimization methods, the game theory.The technique defines the main standard types of activity and operations which are expedient for carrying out for counteraction to sources of threats and risks. The set of actions is divided into four types: blocking, asymmetrical answer, demonstration of force, direct influence. The main groups of corrective actions concerning subjects of various type are considered: natural and legal entities, residents and nonresidents. Accounting of motives of activity of subjects of threats and risks is provided. Types of motives are considered. The general scheme of organization of events on neutralization of sources of threats and risks is offered. Criteria for selection of corrective actions, including optimization of expenses, a possibility of response, various side and system effects are considered.The scientific basis of creation of regulations of organization of events of neutralization of threats and risks, the organizations of training courses, carrying out scenario modeling and creation of the appropriate human-machine technologies of development of counteraction to subjects of threats is developed.