bluuebunny/crossref_metadata_2025_split huggingface dataset:
Renal Sympathetic Denervation by Image-Guided Percutaneous Ethanol Injection – Histopathologic Characteristics, Efficacy and Safety
Authors: Freyhardt Patrick , Haage Patrick , Walter Anna , Aufmesser-Freyhardt Birgit , Guenther Rolf W. , Streitparth Florian 
Published: January 2020

Purpose Evaluation of the efficacy and safety of chemical renal denervation by image-guided periarterial ethanol injection in pigs with emphasis on histopathological characteristics.
Materials and Methods Unilateral renal periarterial ethanol injection under general anesthesia was performed in 16 animals with the contralateral kidney serving as the control. All interventions were performed in an open MRI system under real-time multiplanar guidance. In 10 pigs an ethanol-carbostesin contrast agent mixture was injected with amounts of 5 ml (6 animals, group I) and 10 ml (4 animals, group II). 6 pigs (group III) were treated with 10 ml of an ethanol-polyacrylic (2 %) mixture. Four weeks after treatment, all animals underwent MRI including MRA. After euthanasia, macroscopic and histologic examination of the kidneys, renal arteries and periarterial tissue was performed to assess nerve injury and potential side effects. Furthermore, the norepinephrine concentration (RTNEC) in the renal tissue was determined as a surrogate parameter of efficacy.
Results Histologic signs of nerval degeneration with various degrees of severity and circumferential distribution were found in all groups. Injury depths ranged up to 7.6 mm. In groups II and III the nerve count was significantly lower on the treated side. Renal artery stenosis was not observed in any pig. In all pigs of group II treatment resulted in neural degeneration with a mean RTNEC reduction of 53 % (p < 0.02). In groups I and III significant changes in RTNEC were not observed.
Conclusion Image-guided percutaneous periarterial ethanol injection was efficient and safe for renal denervation. The detected variations in histologic outcome underlined the importance of the preclinical optimization of the technique in order to maximize treatment effects in humans.
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Functional Impact of Tinnitus in Patients with Hearing Loss
Authors: Mantello Erika Barioni , Lupoli Luciana de Mata , Rodrigues Paula Cantarella de Padua , Cavalcante Juliana Maria Soares , Massuda Eduardo Tanaka , Anastasio Adriana Ribeiro Tavares 
Published: January 2020

Abstract
Introduction Tinnitus, which is considered the third worst symptom for humans, is a common complaint among people living with hearing loss and may negatively affect the quality of life of those who have it.
Objective To analyze the perception of the handicap in patients with tinnitus and hearing loss as well as the possible associations between the variables hearing loss, loudness, onset, frequency and annoyance by tinnitus, and the correlation between the visual analogue scale (VAS) and the Tinnitus Handicap Inventory (THI).
Methods A total of 30 patients with complaints of tinnitus and the presence of sensorineural hearing impairment were selected for this cross-sectional, observational, and descriptive study. The loudness of the tinnitus was measured by a VAS and classified as mild, moderate, or severe. The THI was classified as slight, mild, moderate, severe, and catastrophic. Data were submitted to statistical analysis using the Fisher exact test and Spearman correlation coefficient.
Results Eleven male (36.7%) and 19 female (63.3%) subjects with a mean age of 56.5 years old were evaluated. There was no significant association between loudness, annoyance, time and frequency of tinnitus, nor between hearing loss and tinnitus. There was a significant association between the variables hearing loss and loudness, and a weak correlation between VAS and THI.
Conclusion Tinnitus has a practical impact in the lives of patients with hearing loss in terms of catastrophic, functional, and emotional aspects, regardless of loudness, frequency, or time of onset. Hearing loss was a factor that had an impact on the loudness of tinnitus. There was no statistically significant correlation between VAS and THI.
Adult Otogenic Meningitis in the Pneumococcal Conjugated Vaccines Era
Authors: Marom Tal , Shemesh Shay , Habashi Nadeem , Gluck Ofer , Tamir Sharon Ovnat 
Published: January 2020

Abstract
Introduction Streptococcus pneumoniae is a major pathogen of otogenic meningitis (OgM), the most commonly reported intra-cranial complication of otitis media (OM).
Objectives To study the changes in adult OgM patients in the pneumococcal conjugated vaccines (PCVs) era.
Methods Retrospective cohort of adults presenting with concurrent OM and meningitis in a secondary medical care center between 2005 and 2015. Data collected included demographics, OM-related symptoms, cerebrospinal fluid (CSF) and ear culture results, pre- and during hospitalization antibiotic treatment, imaging findings, and complications. We compared the pre-PCV years (2005–2009) with the post-PCV years (2010–2015). Outcomes were 1) incidence of all-cause adult OgM from the total meningitis cases; 2) impact of PCVs on the clinical presentation of OgM and bacteriology.
Results Otogenic meningitis was diagnosed in 26 out of 45 (58%) cases of all-cause meningitis admissions. Of those, 10 (38%) were male, with a mean age of 62.4 years old. Ear-related signs and symptoms were documented in 70% of the patients, and OgM was diagnosed following imaging studies in 6 out of 26 (23%) patients. All of the patients received intravenous antibiotic therapy, and 7 (27%) patients required surgical interventions: 6 required myringotomy and 1 required mastoidectomy. There were 12 (46%) patients in the pre-PCV years and 14 (56%) in the post-PCV years. The positive pneumococcal CSF and ear culture rates remained high and unchanged (∼ 75%). There were no significant changes in the clinical presentation or mortality rates.
Conclusion Micro-otoscopy should be included in the routine work-up of any suspected adult meningitis, because OgM is underdiagnosed. Unlike their impact on pediatric otitis media, PCVs did not change the epidemiology and bacteriology of OgM.
Malignancy Rate in Thyroid Nodules with Atypia or Follicular Lesion of Undetermined Significance
Authors: Pasha Hamdan Ahmed , Dhanani Rahim , Mughal Ainulakbar , Ahmed Kaleem S. , Suhail Anwar 
Published: January 2020

Abstract
Introduction Atypia of undetermined significance (AUS) or follicular lesion of undetermined significance (FLUS) is one of the six diagnostic categories of the Bethesda System for Reporting Thyroid Cytopathology. The prevalence of malignancy among Bethesda category III cytology is variable, ranging from 5% to 37% in the literature.
Objective To determine the rate of malignancy in thyroid nodules reported as Bethesda category III.
Methods A total of 495 patients underwent surgical intervention for thyroid nodules from January 2015 to December 2017. The present study included 81 cases reported as Bethesda category III, and their medical records were reviewed.
Results Out of 495 fine-needle aspiration cytology samples, 81 (16.4%) samples were labeled as AUS/FLUS. Among these 81 patients, the mean age was 43.0 years (± 13.9), with only 11 (14%) patients older than 55 years of age. Most of our patients were female (n = 69; 85.2%), and the rest were male. The rate of malignancy based on the final histology was of 33.3% (n = 27). The majority were 17 cases (21%) of papillary carcinoma, followed by follicular carcinoma (n = 6) (7.4%).
Conclusion The risk of malignancy can be higher than it is commonly believed, and guidelines should be based on the data from the institutions themselves for a better assessment of the outcomes.
Image of the Month: Meconium Peritonitis with Pseudocyst—A Spot Diagnosis in Newborns
Authors: Ascherl Rudolph , Vaz Pimentel Duarte , Knüpfer Mathias , Sorge Ina , Lacher Martin , Zimmermann Peter 
Published: January 2020

AbstractWe report on a male preterm newborn with a large abdominal tumor found on prenatal ultrasound 2 weeks prior to delivery at 36 + 0 weeks of gestation. A postnatal abdominal plain film showed a mass with well-defined rim calcifications (“eggshell”), suggestive of a meconium pseudocyst. On the 4th day of life, the boy underwent exploratory laparotomy with resection of the cyst and end-to-back jejunojejunostomy. The postoperative course was uneventful. A meconium pseudocyst is the correlate of a sterile peritonitis caused by antenatal bowel perforation. It is an easily recognizable spot diagnosis any pediatrician and pediatric surgeon should be aware of.
Archaeological evidence for two separate dispersals of Neanderthals into southern Siberia
Authors: Kolobova Kseniya A. , Roberts Richard G. , Chabai Victor P. , Jacobs Zenobia , Krajcarz Maciej T. , Shalagina Alena V. , Krivoshapkin Andrey I. , Li Bo , Uthmeier Thorsten , Markin Sergey V. , Morley Mike W. , O’Gorman Kieran , Rudaya Natalia A. , Talamo Sahra , Viola Bence , Derevianko Anatoly P. 
Published: January 2020

Significance
Neanderthals once inhabited Europe and western Asia, spreading as far east as the Altai Mountains in southern Siberia, but the geographical origin and time of arrival of the Altai populations remain unresolved. Excavations at Chagyrskaya Cave in the Altai foothills have yielded 90,000 stone artifacts, numerous bone tools, 74 Neanderthal fossils, and animal and plant remains recovered from 59,000- to 49,000-year-old deposits. The Chagyrskaya Neanderthals made distinctive stone tools that closely resemble Micoquian artifacts from eastern Europe, whereas other Altai sites occupied by earlier Neanderthal populations lack such artifacts. This suggests at least two dispersals of Neanderthals into southern Siberia, with the likely ancestral homeland of the Chagyrskaya toolmakers located 3,000 to 4,000 kilometers to the west, in eastern Europe.
Fig (Ficus caricaL.) leaf tea suppresses allergy by acceleration disassembly of IgE-receptor complexes
Authors: Abe Tatsuya 
Published: January 2020

AbstractIn this study, I investigated the allergy suppressive effect of tea made from fig (Ficus carica L.) leaves. In the rat basophil cell line RBL-2H3, degranulation was significantly suppressed by treatment with fig tea at the same time as addition of IgE antibodies (sensitization). IgE bound to the cell surface was liberated in the medium depending on the treatment time with fig tea. Therefore, it was suggested that the mechanism of action of fig tea is promotion of dissociation of IgE from FcεRI receptors. Such a mechanism is novel in food materials. On oral administration to mice, fig tea showed an inhibitory effect on allergic dermatitis. Furthermore, in tests using an atopic dermatitis model in NC/Nga mice, continued administration of fig tea suppressed symptom exacerbation after antigen administration.AbbreviationsAD: atopic dermatitis; β-Hex: β-hexosaminidase; FCM: flow cytometory; OA: oral administration; TA: transdermal administration
Triply heavy baryons in the constituent quark model *
Authors: Yang Gang , Ping Jialun , Ortega Pablo G. , Segovia Jorge 
Published: January 2020

Abstract
The constituent quark model is used to compute the ground and excited state masses of QQQbaryons containing either c or bquarks. The quark model parameters previously used to describe the properties of charmonium and bottomonium states were used in this analysis. The non-relativistic three-body bound state problem is solved by means of the Gaussian expansion method which provides sufficient accuracy and simplifies the subsequent evaluation of the matrix elements. Several low-lying states with quantum numbers

and

are reported. We compare the results with those obtained by the other theoretical formalisms. There is a general agreement for the mass of the ground state in each sector of triply heavy baryons. However, the situation is more puzzling for the excited states, and appropriate comments about the most relevant features of our comparison are given.
Possible Odderon exchange in pp and

elastic collisions at the TOTEM experiment *
Authors: Lu Juan , Zhou Li-Juan , Fang Zhi-Jie 
Published: January 2020

Abstract
Based on the Froissart-Martin theorem, the Regge theory and the possible Odderon exchange, the total cross-section

and the ratio of the real to imaginary parts of the forward scattering amplitude

in the

and

elastic collisions in the TOTEM energy region are studied in the FPO model. We consider the contributions of the Froissart bound and of the Pomeron, Reggeon and Odderon exchange terms in the scattering amplitude of the

and

elastic collisions. Using the Odderon intercept

, our theoretical predictions are in good agreement with the recent results of the TOTEM experiment. These results show that the Odderon, corresponding to the odd elastic scattering amplitude, is likely to exist.
Manganese doping on the structural properties of TiO2 and ZnO nanoparticles
Authors: Djaja N F , Taufik A , Saleh R 
Published: January 2020

Abstract
In this study, manganese (Mn) doped ZnO and TiO2 were synthesized through the co-precipitation method. The Mn doping content was set at 6 atomic percent (at.%), and the physical properties of all prepared samples were investigated using energy dispersive X-ray spectroscopy, X-ray diffraction, UV-Vis spectroscopy, and electron spin resonance measurement. The results show that the anatase structure from TiO2 and hexagonal wurtzite from ZnO remained unchanged with the incorporation of the Mn dopant. The grain size of the corresponding TiO2 and ZnO slightly decreased after Mn incorporation, and the band gap energies of TiO2 and ZnO nanoparticles decreased after Mn doping. The electron spin resonance measurement confirmed the existence of oxygen vacancy from the TiO2 and ZnO lattice and increased with the incorporation of the Mn ion. To investigate the potential applications of the samples, the photocatalytic activity of the samples was evaluated to determine the degradation of malachite green from the aqueous solutions under UV light irradiations.
Digital image steganography by using edge adaptive based chaos cryptography
Authors: Delmi A , Suryadi S , Satria Y 
Published: January 2020

Abstract
Steganography and Cryptography is the method used to secure the information. Cryptography is used the principle of a Chaos by using Cat Arnold Map function to assure randomness. While in steganography, the method is used Least Significant Bit Matching Revisited (LSBMR). Embedding region was on edge digital imagery to ensure the message was not detected in the image by visual. The method used to detect the edge region by using Canny edge Detection. The test results obtained by Peak Signal to Ratio (PSNR) are 72-44 dB for data messages with a size of 10 % of the media cover.
Preparation and characterisation of bismuth-doped TiO2 nanotubes (Bi–TiO2–NT) and its photocatalytic activity test for rhodamine B elimination under visible light
Authors: Aqil M A , Gunlazuardi J 
Published: January 2020

Abstract
As a photocatalyst, TiO2 nanotubes can effectively degrade dyes; thus, they exhibit a considerable potential to mitigate the problem of river pollution by dye waste originating from the textile industry. However, with a band gap of 3.2 eV (UV light energy range), such nanotubes cannot be completely utilizing under visible light from the sun. Therefore, in this study, the TiO2 nanotubes are modified using bismuth to obtain bismuth-doped TiO2-NT (Bi–TiO2–NT), which exhibits an activity under visible light. Bi-TiO2-NT was successfully synthesized by one-step anodization with Bi(NO3)3 as the dopant source. The optimum synthesis conditions obtained were as follows: 1.0 M Bi(NO3)3 in an ethylene glycol electrolyte with anodization at 40 V for 1 h. In this study, the synthesized photocatalyst was characterized using X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR), UV-Vis Diffuse Reflectance Spectroscopy (DRS), Scanning Electron Microscopy–Energy Dispersive X-Ray Spectroscopy (SEM-EDS), and Linear Sweep Voltametry (LSV). The results of the photocatalytic activity tests indicated that under visible light illumination the prepared Bi–TiO2–NT was able to eliminate rhodamine B from the tested water, better then bare TiO2.
Synthesis of ion-imprinted polymer with gamma irradiation for the adsorption of Tripolyphosphate
Authors: Anwar S , Saefumillah A , Suhartini M 
Published: January 2020

Abstract
One method of separating tripolyphosphate ion uses ion-imprinted polymer. Chitosan-succinate, tripolyphosphate and methylene bis akrilamida (MBA) were used as the complexing polymer, template, and crosslinker agent, respectively. In the first step, Fe(III)-chitosan-succinate-tripolyphospate was formed. In the second step, Fe(III)-chitosan-succinate-tripolyphospate was crosslinked by MBA and irradiated by gamma rays. Then, tripolyphosphate ion was removed with KOH solution to form a selective cavity for tripolyphosphate ion in the ion-imprinted polymer (IIP). Based on the results of this study, the optimum adsorption of tripolyphosphate ion was found at an MBA crosslinker concentration of 1%, pH 2, irradiation dose 20 kGy, and a tripolyphosphate ion concentration of 1 ppm. This study also included experimental adsorption of tripolyphosphate ion on non-imprinted polymer (NIP-MBA) and an evaluation of the effect of interference ions. The resulting adsorption of tripolyphosphate ion on IIP was found to be higher than those of non-imprinted polymer. The adsorption percentages were found to be 94 % for IIP and 14 % for NIP-MBA. Chloride ion (Cl-) provided greater interference in the adsorption process of tripolyphosphate ion compared to carbonate ions. The percent adsorptions of tripolyphosphates were estimated to be 57.71 % in the presence Cl- ion and 68.28 % in the presence CO3
2−ion.
Selectivity of zinc-molybdenum catalyst to produce gasoil via catalytic hydrocracking of Kapook seed oil (Ceiba pentandra)
Authors: Mirzayanti Y W , Kurniawansyah F , Prajitno D H , Roesyadi A 
Published: January 2020

Abstract
Various type of Zinc (3.25 %) Mo (6.34 %) Hz catalysts have been prepared using incipient wetness impregnation method. The catalysts were characterized by X-ray diffraction (XRD), energy dispersive analysis x-ray (EDAX) and Brunauer-Emmett-Teller (BET) method. The performance of the catalysts, Zinc (3.25 %) Mo (6.34 %) Hz was investigated for the catalytic hydrocracking of Kapook seed oil (KSO) to hydrocarbon biofuel in a slurry pressure batch reactor system with a stirrer. The hydrocracking reaction was carried out at reaction temperatures from 300-400 °C and reactor pressure of 15 bar for 2 h under H2 flowing. The effect of reaction temperature on composition of hydrocarbon compounds, n-paraffin, conversion and selectivity in liquid products was studied with a variation of ZincMoHz catalysts. It showed the highest hydrocarbon content decarboxylation and/or decarbonylation were 18.61 area% of n-paraffin and the highest content for gasoil-range alkanes was 10.44 area% obtained at 400 °C. The result show that the Zinc (3.25%) Mo (6.34%) Hz catalyst activity was found that the gasoil fraction which triglycerides where cracked with long carbon double bonds chains over Zinc (3.25%) Mo (6.34%) Hz catalyst.
The effect of sulphuric acid and oxalic acid on the formation of anodic aluminium oxide templates using two-step anodization method
Authors: Syamdri F D , Wibowo R 
Published: January 2020

Abstract
The prevention of corrosion on the surface of aluminum by formation of a thin coating layer using anodization methods for enhanced applications is an active area of research. In this study, the fabrication of nanoporous anodic aluminum oxide (AAO) templates was performed by a two-step anodization process using aluminum with 99.98% purity in 0.3 M solution of oxalic acid or 0.1, 0.3, or 0.5 M solutions of sulfuric acid as electrolyte. Anodizing time, electrolyte solution and concentration, and current were found to be the main factors determining the pore diameter and interpore size. In addition, the voltage affected the number of pores on the AAO template. The structural features of the nanoporous templates were examined by scanning electron microscopy. The optimum conditions were determined to be 0.3 M sulfuric acid at 25 V.
Cloning gene encoding lysophospholipase from Bacillus halodurans CM1 to Escherichia coli DH5α
Authors: Fernanda S , Abinawanto A , Helianti I 
Published: January 2020

Abstract
Enzyme is a biocatalyst that is widely used in industry, for example detergent, pharmaceutical, food or oil purification. One of the most widely using enzymes for oil purification is lysophospholipase. As much as 50% of the needs of industrial enzyme are obtained from microorganisms. However, enzyme productivity of these wild type microbial strains is usually limited and cannot be applied in industry, so a genetic engineering is necessary. Cloning gene encoding for lysophospholipase was once performed in Aspergillus niger and Cryptococcus neoformans, but has never been conducted from alkalothermophilic bacteria, such as Bacillus halodurans. Bacillus halodurans CM1 is an isolate from Badan Pengkajian dan Penerapan Teknologi (BPPT). Previous research has shown that these bacteria have lipase enzymes, but the study about their properties have not been conducted. This study aims to clone the gene lysophospholipase from Bacillus halodurans CM1 to Escherichia coli DH5α using the pGEM-T easy vector. The recombinant plasmid is sequenced. The gene fragment encoding lysophospholipase was successfully obtained with size 783 base pairs and 100% similarity with gene encoding lysophospholipase from Bacillus halodurans C-125 (No access GenBank: BA000004.3).
Variation of seawater temperature and chlorophyll-a prior to and during upwelling event in Bali Strait, Indonesia: from observation and model
Authors: Rintaka W E , Priyono B 
Published: January 2020

Abstract
Coastal upwelling event can be observed clearly from drastic changes of seawater temperature and chlorophyll-a before and during the event. From observation and model output, time-series data of these variables provide important datasets to be used for further analysis, such as developing gaussian empirical model of net marine primary productivity (NPP). Here, the objectives of this study are to analysis variation of temperature and chlorophyll-a (chl-a) from both observation and model output datasets, and to evaluate model temperature and chl-a for estimating the NPP prior to and during the upwelling event in Bali Strait. The archive CTD collected in April, June and August 2013 and model output datasets were used in this study. It is shown that during peak of upwelling event in August 2013, observed temperature is minimum and chl-a is maximum in the upper 50 m depth. It is found surfacing isotherm of 25-26°C from sub-surface to sea surface. Furthermore, model output of temperature was in good agreement with observed data, complementing the evolution of upwelling for entire year. Estimated NPP from empirical model suggested that a high NPP distribution occurred in the eastern part of Bali Strait during peak of upwelling event.