bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Medium Supplements in Terms of the Effects on the Differentiation of SH-SY5Y Human Neuroblastoma Cell Line
Authors: Serdar Belgin Sert , Erkmen Tuğba , Ergür Bekir Uğur , Akan Pınar , Koçtürk Semra 
Published: June 2020

Objective:
Human SH-SY5Y cell line has been frequently used for in vitro experiments in neuroscience-related research. To reflect a better neuronal characteristic the cell line needs to a differentiation. To compare the results obtained from in vitro models, the similarity of the phenotype and characteristic of the cells has great importance. However, many studies have been performed using the different medium ingredients which affect the differentiation progress of the cells. Therefore, we aimed to compare generally used differentiation mediums, contain only retinoic acid (RA) and supplemented with different ingredients, in the aspect of neuron-like phenotype characteristics and stability.

Materials and Methods:
The effects of medium ingredients on differentiation levels were evaluated using morphological changing, neurite length, and immunofluorescence detection of neuronal markers such as NFH, β-III Tubulin, and microtubule-associated protein 2 (MAP2). The stability of differentiated cells was followed microscopically at the 7th, 10th, and 14th days by morphological changings and neurite length using Neuron J software.

Results:
The results revealed that the cells pretreated with RA for 5-day treatment and followed by 5-day treatment with the mix medium and brain-derived neurotrophic factor (BDNF), provided significantly higher neurite length than the other groups (P < 0.001). In this group, the expressions of β-tubulin III, MAP2, and NF-H were also significantly higher than the control group (P < 0.05, P < 0.001, and P < 0.05, respectively) and differentiated cells were stable until the 7th day.

Conclusion:
The results demonstrated that enriched mediums are necessary for a better differentiation of SH-SY5Y cells. We recommend 10-day treatment period and using of RA, BDNF, dc-AMP, KCI together in SH-SY5Y cell differentiation.
Bilateral Nerve Conduction Studies Must Be Considered in the Diagnosis of Sciatic Nerve Injury Due to Intramuscular Injection
Authors: Fidanci Halit , Öztürk İlker , Köylüoğlu Ahmet Candan , Yıldız Mehmet , Arlıer Zülfikar 
Published: June 2020

Objectives:
Although compound muscle action potential (CMAP) and sensory nerve action potential (SNAP) amplitudes of the nerves are reduced in sciatic nerve injury due to intramuscular injection (SNIII), they may still be higher than the reference values if there is a mild axonal degeneration. In this case, comparing the outcomes of nerve conduction studies of intact and affected lower extremities becomes important. We aimed to determine the role of this comparison in the diagnosis of SNIII.

Methods:
Patients with SNIII were included. Reference values for lower extremity nerve conduction studies were obtained from healthy participants. Peroneal, posterior tibial, superficial peroneal, and sural nerve conduction studies were performed in both lower extremities. In the first analysis, the CMAP or SNAP amplitude of the nerve was considered abnormal if it was less than the reference value. In the second analysis, the CMAP or SNAP amplitude of the nerve was considered abnormal if it was less than the reference value or <50% of the CMAP or SNAP amplitude obtained from the intact limb nerve.

Results:
Thirty patients and 31 controls were included in the study. Compared with those found in the first analysis, the number of posterior tibial nerve CMAPs with reduced amplitudes, and the sural and superficial peroneal nerve SNAPs with reduced amplitudes were higher in the second analysis (P = 0.008, P < 0.001, and P = 0.031; respectively).

Conclusion:
This study showed that nerve conduction studies should be performed in both the intact and affected extremities in SNIII.
Electrodiagnostic Patterns of Demyelination and Hughes Functional Grading in Typical Chronic Inflammatory Demyelinating Polyneuropathy
Authors: Towman Fatin Hatim , Hamdan Farqad Bader 
Published: June 2020

Background:
Chronic inflammatory demyelinating polyneuropathy (CIDP) is characterized by progressive or relapsing motor or sensory symptoms, with variants differing in the relative distribution of these symptoms and electrophysiologic findings. We aimed to correlate the electrodiagnostic patterns of demyelination using Hughes Functional Grading Scale in patients with CIDP.

Methods:
A case–control study was conducted at the neurophysiology department of Al-Imamian Al-Kadhymian Medical city and Nursing Home Hospital, Medical City, Baghdad from December 2017 to June 2018. Fifteen patients with CIDP aged 30–60 years with disease duration between 6 months and 2 years and 20 age-matched healthy subjects (control group) were included in the study. The participants were submitted to medical history, clinical neurological examination, and electrophysiologic tests.

Results:
Patients with CIDP demonstrated prolonged distal sensory and motor latencies, decreased sensory nerve action potential amplitude, slowing of sensory and motor nerve conduction velocity, and prolonged mean F-wave latency. The majority showed absent sural sensory responses. Significant relationships were demonstrated between the Hughes Functional Grading Scale and different neurophysiologic parameters, and no correlation was found with the terminal latency index.

Conclusions:
Patients with high Hughes functional scoring also have severe abnormalities in motor parameters, usually in the range of demyelination. The involvement of nerve segments was multifocal affecting mostly the proximal and intermediate nerve segments; the terminal segments were involved to a lesser extent.
Variation of constants formula and exponential dichotomy for nonautonomous non-densely defined Cauchy problems
Authors: Magal Pierre , Seydi Ousmane 
Published: June 2020

AbstractIn this paper, we extend to the non-Hille–Yosida case a variation of constants formula for a nonautonomous and nonhomogeneous Cauchy problems first obtained by Gühring and Räbiger. By using this variation of constants formula, we derive a necessary and sufficient condition for the existence of an exponential dichotomy for the evolution family generated by the associated nonautonomous homogeneous problem. We also prove a persistence result of the exponential dichotomy for small perturbations. Finally, we illustrate our results by considering two examples. The first example is a parabolic equation with nonlocal and nonautonomous boundary conditions, and the second example is an age-structured model that is a hyperbolic equation.
Bounding the Iwasawa invariants of Selmer groups
Authors: Kleine Sören 
Published: June 2020

AbstractWe study the growth of p-primary Selmer groups of abelian varieties with good ordinary reduction at p in

${{Z}}_p$
-extensions of a fixed number field K. Proving that in many situations the knowledge of the Selmer groups in a sufficiently large number of finite layers of a

${{Z}}_p$
-extension over K suffices for bounding the over-all growth, we relate the Iwasawa invariants of Selmer groups in different

${{Z}}_p$
-extensions of K. As applications, we bound the growth of Mordell–Weil ranks and the growth of Tate-Shafarevich groups. Finally, we derive an analogous result on the growth of fine Selmer groups.
Impact to information computer technology: computer competency of Tinajero high school teachers in Philippines
Authors: Gamboa Jerame , Gamboa Alberto G. 
Published: June 2020

This study aims to describe the computer competency of high school teachers at Tinajero High School, in the Philippines, during the calendar year 2019. Specifically, it sought to identify and describe the teachers’ computer competency, strengths and weaknesses, and problems in MS Word, Excel, and PowerPoint. Most of the conducted studies focused on the computer competency of the students. Few studies addressed the computer competency level of the teachers. In this digital age, teachers are not exempted on learning he Microsoft application. Sooner or later, the world will be embracing a mode of instruction that uses more of computer than of those traditional ways. This study used a descriptive-survey type of study and a validated competency test from Module quizzes from Innovate: A Mentor’s Guide to ICT Foundation Competencies by Microsoft Philippines. Findings showed the teachers are highly competent on MS Word, competent on MS Excel, and MS PowerPoint. Insufficiency of the computer equipment was identified as the main problem. It is therefore recommended to further strengthen the ICT capability training being given to the teachers so that technology will be maximized in making the educative system more impactful to the learners.
New tools of the influence of employers on the education and personnel training system in Russia
Authors: Chaplinsky S. I. 
Published: June 2020

Providing rail transport with qualified personnel has traditionally been in the realm of close attention. Modern realities dictate the need to search for and implement effective tools for the interaction of the education system and employers, which can influence the training of personnel.Thanks to the development of the national qualifications system in Russia, employers and the education system have received effective tools for interaction in the form of professional and public accreditation and independent qualifications assessment, which allow taking into account the requirements of employers, current trends and technologies of production organization, and assess willingness of students to perform specific labor functions in accordance with approved professional standards.Rail transport has been actively involved in the implementation of elements of the national qualifications system, including professional and public accreditation and independent assessment of qualifications. The implementation of these measures should become an important mechanism in improving the professional level of railway workers and building an effective barrier for people who are not ready for responsible work in this area.The considered tools of the national qualifications system contribute to the formation of responsible interaction of all stakeholders in the quality of learning outcomes.
Yuri Vyacheslavovich Grdina — king of russian rails
Authors: Pokrovskaya O. D. 
Published: June 2020

The work is dedicated to the 75th anniversary of the Victory in the Great Patriotic War, the contribution of Siberian science and industry to our Victory.The activities of the great scientist, who worked for a long time in the Kemerovo region, at the Siberian Metallurgical Institute (now Siberian State Industrial University, Siberian State Industrial University, Novokuznetsk) are considered. Yuri Vyacheslavovich Grdina, truly — the king of rails, a man of legend.In 2021, the 120th anniversary of the birth of the great scientist will be celebrated. The railway network of Russia is woven from its rails.Reflected not only the professional activities of Grdina — a scientist, but also revealed his multifaceted personality as a creative person who was fond of painting, photography, boating, chess, literature.
EFEKTIVITAS RANGE OF MOTION (ROM) AKTIF TERHADAP KEKUATAN OTOT EKSTREMITAS ATAS DAN EKSTREMITAS BAWAH PADA LANSIA
Authors: Hartinah Siti , Pranata Lilik , Koerniawan Dheni 
Published: June 2020

Lansia mengalami perubahan fisiologis dan morfologis pada system muskuloskeletal khususnya otot yaitu adanya penurunan kekuatan otot dan massa otot. Mengetahui analisis efektifitas ROM aktif terhadap kekuatan otot ekstremitas atas dan ekstremitas bawah pada lansia di Panti Tresna Werdha Teratai KM. 6 Palembang.Penelitian ini menggunakan desain Quasy Experiment dengan pendekatan Pre-Post Test Non Equivalent Control Grup terhadap 18 responden dengan teknik total sampling. ROM aktif dilakukan 3 kali dalam seminggu dengan durasi 30 menit dan diulang sebanyak 3 kali pada tiap ekstremitas. Friedman dan Mann-Whitney digunakan untuk analis bivariat.Mayoritas dalam kelompok intervensi memiliki skala kekuatan otot 4 dan 5 dan kelompok kontrol memiliki skala kekuatan otot 4.Uji Friedman menunjukkan perbedaan yang signifikan pada ekstremitas atas (p=0,001) dan ekstremitas bawah (p=0,008). Uji Mann-Whitney menunjukkan perbedaan yang signifikan pada ekstremitas atas (p=0,03) setelah intervensi ROM aktif, tetapi tidak signifikan pada ekstremitas bawah (p=0,058). Lansia dan Panti Tresna Werdha Teratai diharapkan dapat melakukan latihan ROM aktif dan memprogramkan secara rutin karena latihan ini terbukti dapat meningkatkan kekuatan otot.
PENGARUH LUAS LAHAN SAWAH DAN LUAS TANAM TERHADAP PRODUKSI PADI DI SUMATERA SELATAN MELALUI ANALISIS REGRESI
Authors: Defriyanti Wenni Tania 
Published: June 2020

Lahan sawah memiliki fungsi strategis, merupakan penyedia bahan pangan utama bagi penduduk Indonesia. Lahan sawah di Provinsi Sumatera Selatan terdiri atas lahan irigasi, tadah hujan, pasang surut dan lebak. Pemanfaatannya dengan penanaman padi menempatkan posisi Sumatera Selatan sebagai penyumbang produksi keenam terhadap produksi padi nasional. Kajian menggunakan pendekatan kuantitatif dengan metode analisis regresi sederhana dan regresi berganda. Analisis regresi sederhana dilaksanakan antara peubah luas lahan dan peubah luas panen padi, masing-masing dengan produksi padi. Analisis regresi ganda dilaksanakan antara peubah luas lahan dan luas panen dengan produksi padi. Dari hasil analisis menunjukkan bahwa Banyuasin merupakan kabupaten yang memiliki total areal lahan sawah terluas yaitu 202.682ha, dan OKU Timur merupakan kabupaten yang memiliki areal tanam padi terluas yaitu 179.307ha, serta merupakan penghasil produksi padi terbanyak yaitu 1,162.123ton. Luas lahan sawah (X1) dan luas tanam (X2) sangat berpengaruh positif dan signifikan terhadap produksi padi (Y) di Kabupaten/Kota Provinsi Sumatera Selatan dengan tingkat korelasi sebesar 94% (tinggi).
Complejidad e Incertidumbre en la Gestión Pública, para coadyuvar a la Gestión del Desarrollo en El Salvador, 1989-2019. Repensamiento de la Gestión Pública, desde el Gobierno Inteligente
Authors: Menjívar Erick 
Published: June 2020

La primera versión del presente artículo fue presentada el 20 de febrero, antes que la Organización Mundial de la Salud (OMS) declarara al COVID 19 como pandemia mundial. Ello se destaca pues, el binomio “complejidad e incertidumbre” en el contexto de la emergencia sanitaria mundial muestra las graves falencias de la gestión pública salvadoreña, independientemente del Gobierno de turno, en ámbitos relevantes para el desarrollo humano. Acá, se presenta una lectura de la gestión económica y del desarrollo, 1989-2019, la cual se caracteriza como un escenario de complejidad e incertidumbre para promover el bienestar, que no debe entenderse como inviabilidad de nación; pero sí, como un imperativo para un repensamiento de la gestión pública, desde el Gobierno Inteligente; para coadyuvar a la gestión del desarrollo en el país, al tiempo que se gestiona la complejidad e incertidumbre.
Realidad Virtual y desarrollo de competencias de reconocimiento y empatía contra la violencia de género
Authors: Vázquez Parra José Carlos 
Published: June 2020

En los últimos años, la innovación tecnológica aplicada al aula permite apreciar un mayor uso de herramientas para mejorar los procesos de formación de los futuros profesionistas; sin embargo, ¿qué tanto pueden las TIC abonar al mejoramiento de las competencias sociales y humanistas? El presente artículo tiene por objetivo hacer una reflexión sobre el impacto de la realidad virtual en el desarrollo de las competencias transversales de reconocimiento y empatía, enfocándose en un tema concreto, la violencia de género. Para conseguirlo, se llevó a cabo un estudio e implementación en estudiantes de una universidad mexicana, logrando identificar diferencias significativas en el desarrollo final de estas competencias.
De reikwijdte van de term ‘opzettelijk’ in artikel 2 lid 1 Wet op de economische delicten
Authors: Koopmans I.M. 
Published: June 2020

De reikwijdte van de term ‘opzettelijk’ in artikel 2 lid 1 Wet op de economische delicten
In een arrest van september 2019 koppelt het Hof Arnhem de ‘wist-variant’ van de ten laste gelegde gevaarzetting aan de vraag of sprake is van opzettelijke overtreding van artikel 32 Arbeidsomstandighedenwet. Het hof spreekt vrij van die wetenschap en tegelijk daarmee ook van opzettelijke overtreding van artikel 32 Arbeidsomstandighedenwet. Vervolgens wordt slechts de overtredingsvariant bewezen geacht. In deze bijdrage zal worden uiteengezet waarom het hof hiermee de systematiek die ten grondslag ligt aan de Wet op de economische delicten (WED) miskent.
Naschrift bij ‘Het belang van privacy in het strafrecht’
Authors: Peterson P.C. 
Published: June 2020

Naschrift bij ‘Het belang van privacy in het strafrecht’
De openbaarheid van rechtspraak is een fundamentele pijler van de democratische rechtsstaat. Daar staat tegenover dat een verdachte of veroordeelde grote waarde hecht aan anonimiteit in het strafproces. Gerechten dienen bij de publicatie van strafrechtelijke informatie deze anonimiteit te waarborgen. Maar hoe is het toezicht hierop geregeld? Wat gebeurt er als bij het beschikbaar stellen van informatie over gerechtelijke (straf)zaken de Algemene verordening gegevensbescherming of de Wet justitiële en strafvorderlijke gegevens wordt geschonden? Is de Autoriteit Persoonsgegevens bevoegd een boete op te leggen? In dit naschrijft bij het artikel ‘Het belang van privacy in het strafrecht’ worden deze vragen beantwoord.
Satellite Based Interpretation of Stability Parameters on Convective Systems over India and Srilanka
Authors: Umakanth Nandivada , Satyanarayana Gubbala China , Simon Baby , Rao Myla Chimpiri 
Published: June 2020

Abstract
India is frequently exposed to convective systems (CS) during the hot period of pre-monsoon season. Huge thunderstorms are more often over India in the recent years. To analyze these systems, the stability parameters considered as good precursors for understanding the physics of the convective systems in prior to their occurrence. The present study is concerned about the analysis of stability parameters such as K Index (KI), Lifted Index (LI), Total Totals Index (TTI), Humidity Index (HI), Convective available potential energy (CAPE), Convective Inhibition (CIN), Lifting Condensation Level (LCL) and Level of free Convection (LFC) associated with severe convective systems over India and Srilanka during April, 2015. First, INSAT-3D satellite based brightness temperature (BT) product was used for analyzing the initial, mature and dissipation stages of the convective system at every 30 min interval. The data products from MODIS Terra satellite, MODIS Aqua satellite, Era-Interim ECMWF reanalysis satellite data and IASI satellite were used for understanding the thermodynamics related to the occurrence of these convective systems. The results of stability parameters that were derived from MODIS Terra and Aqua satellite’s data products indicated the favorable threshold values for the occurrence of convective systems. Results from Era-Interim ECMWF reanalysis satellite data also helps us to understand the dynamics involved behind the convective system. The results from IASI satellite also helped us to understand the severity of convective systems during cloudy situations. The results of this study impulse the need of satellites for analyzing the convective systems prior to their occurrence.
Der Anfang des Ganzen
Authors: Polaschegg Andrea 
Published: June 2020

Aus einer materialgesättigten Medienpoetik des Textanfangs wird hier eine völlig neue Ästhetik der Literatur entwickelt.

Texte haben Anfänge. Sie beginnen mit einem ersten Satz, einem ersten Vers oder einem ersten Akt, auf den alles Weitere folgt - unabhängig davon, wo ihre Lektüre einsetzt. Dinge dagegen besitzen solche Anfänge nicht. An ihnen lassen sich Grenzen, Ränder oder Kanten ausmachen, bestenfalls zwei Enden, aber kein Anfang.
Diese scheinbar simple Einsicht birgt einen medien- und literaturtheoretischen Sprengstoff, den Andrea Polaschegg zündet: Obwohl Texte durch ihre Anfänge als Verlaufsmedien erkennbar werden, die von Bildern ebenso kategorial unterschieden sind wie von Gegenständen, haben Ästhetik und Literaturwissenschaft diese Eigengesetzlichkeit des Textes ausgeblendet und literarische Werke stets nur als simultane Ganzheiten begriffen.
Anhand zahlreicher Beispiele aus der Literatur-, Kunst- und Theoriegeschichte entwickelt die Autorin eine Medienpoetik, die den transitorischen Charakter des Textes ernst nimmt, und entwirft auf dieser Grundlage eine neue Ästhetik der Literatur. Der Textanfang präsentiert sich dabei als eminente Herausforderung überkommener Denkgewohnheiten. Und die Suche nach den Gründen für die literaturwissenschaftliche Verlaufsvergessenheit legt unerwartete Traditionen frei.
Childcare and Development of Paediatrics in Moravia (Czech Republic) in the Context of Palaeopathological Research Focusing on Congenital Malformations, Metabolic and Haematologic Diseases
Authors: Vargová Lenka , Vymazalová Kateřina , Horáčková Ladislava 
Published: June 2020

Prezentovaná práce je součástí komplexní studie zaměřené na sledování původu a vývoje pediatrické péče na Moravě, jedné ze zemí dřívější Rakouské monarchie. Studie také bere v potaz sociální podmínky jako změny moravského zdravotnictví ve studovaném období v souvislosti s tereziánskými a josefínskými reformami. Novorozenecká úmrtnost byla v té době velmi vysoká, což souviselo i s nedostatkem péče o těhotné ženy. Studie sleduje zdravotní stav a příčiny úmrtí dětí od 13. do 19. století, na základě studia dostupných literárních zdrojů v kontextu paleopatologické analýzy dětských kosterních pozůstatků. Analýza koster dospělých jedinců sledované populace poskytuje důkaz vysoké úmrtnosti žen ve věku 20–30 let. Pozornost byla zaměřena na vrozené malformace, metabolická a hematologická onemocnění. Z vrozených malformací potvrdila paleopatologická analýza u dětské populace vývojovou dysplázii kyčelního kloubu a předčasnou obliteraci lebečních švů. Z hematologických a metabolických chorob byla nejčastěji zaznamenány známky anemie ve formě cribra orbitalia a stopy po kurdějích a křivici. Tyto choroby se nejčastěji vyskytovaly u dětí v chudobincích a sirotčincích. Podle literárních zdrojů jejich výskyt významně vzrůstal v závislosti na válečných událostech provázených hladomorem. Výsledky studie poskytují přímý důkaz výskytu sledovaných dětských nemocí na Moravě v období novověku.