bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENINGKATAN KINERJA BISNIS MELALUI STRATEGI PEMASARAN BERBASIS ONLINE PADA UKM PRODUK CAMILAN TRADISIONAL
Authors: ISTIQOMAH Suryandari , FAJARYANTI Yeni , DEWI Amina Sukma 
Published: May 2020

The internet is one of the technologies that is inevitable in today's digital era. One effect of the internet is also having an impact on the business world, among others, with the development of e-commerce and the decreasing number of offline retailers. therefore the use of internet / e-commerce as an alternative sale must be made by all entrepreneurs including traditional snack entrepreneurs.
This research aims to be able to help SMEs to introduce products through sales through the internet and its derivatives. In addition, this service also aims to introduce traditional snack products with better marketing strategies, including by using more eye catching packaging and selling so that they can be easily accepted by millennials.
This research has carried out several activities including operational training in marketing training on the importance of attractive brands and packaging, as well as online marketing. This service has helped provide assistance in making stickers, cardboard boxes and jars as a diversification of product packaging for UKM Kembang Goyang “Bu Ninik”, Sragen. This dedication also initiates the use of gift boxes as a respondent to the beautiful appearance of souvenirs. In UKM Kumari Crispi, this research carried out by initiating product innovations with various flavors that are of interest to millennialsand providing shelter assistance for Kumari Crispy souvenir shops to support online businesses that will be run. All of training and accompaniment hope can improve the business performance of the target SMEs by increasing the demand for their products.
ANALISA KELAYAKAN WILAYAH UNTUK PEMBANGUNAN FLOATING DOCK SEBAGAI DOK ALTERNATIF DI KEPULAUAN MALUKU MENGGUNAKAN FAHP-TOPSIS
Authors: Tukan Marcus , Camerling Billy Jhones , Afifudin Mohammad Thezar , Hozairi Hozairi 
Published: May 2020

Galangan kapal berfungsi sebagai tempat untuk mereparasi, merawat dan membangun kapal sesuai kebutuhan pemiliknya. Ketersediaan fasilitas di wilayah Maluku cukup beragam tergantung bobot kapal yang dapat dilayani. Jumlah galangan kapal yang bisa melakukan pekerjaan pemeliharaan dan perbaikan kapal di wilayah Propinsi Maluku sangat sedikit, sehingga menyebabkan antrian kapal yang mau docking, akibatnya banyak perusahaan terpaksa memilih lokasi docking diluar propinsi Maluku. Untuk menyelesaikan permasalahan keterbatasan kemampuan docking kapal di wilayah Maluku, maka sistem floating dock dipilih sebagai alternative docking untuk dikembangkan karena lebih murah dan sangat fleksibel untuk dipindah-pindah. Penelitian ini bertujuan untuk menganalisa aspek yang mempengaruhi pembangunan floating dock serta menentukan lokasi yang tepat untuk pembangunan floating docking di Maluku. Penelitian ini menggunakan kombinasi dua metode yaitu Fuzzy AHP-TOPSIS. FAHP digunakan untuk menentukan tingkat kepentingan antara kriteria kelayakan pembangunan floating dock yang terdiri dari (aspek metereologi, geografi, osenonografi, lingkungan, penduduk, ekonomi dan sarana dan prasarana). Hasil analisa perhitungan dengan metode FAHP-TOPSIS memberikan nilai prioritas keputusan pertama adalah wilayah Dobo (0.41), kedua adalah wilayah Saumlaki (0.31), ketiga adalah wilayah Tual (0.26), dan keempat adalah wilayah Tiakor (0.02). Penelitian ini telah memberikan kontribusi keputusan kepada Pemerintah atau swasta bahwa wilayah yang paling baik untuk dikembangkan pembangunan floating dock adalah wilayah dobo dengan prioritas nilai 41% dibanding tiga wilayah yang lain.
DAMPAK PERTUMBUHAN PASAR MODERN TERHADAP PASAR TRADISIONAL DI KABUPATEN KARAWANG
Authors: Santi Pertiwi Hari Sandi  , Mumun Maemunah  
Published: May 2020

Penelitian ini bertujuan untuk (1) mengetahui kebijakan yang berkaitan dengan pasar tradisional dan pasar modern di Kabupaten Karawang, (2) mengetahui dampak adanya pasar modern terhadap pasar tradisional di Kabupaten Karawang, (3) mengetahui upaya yang dilakukan Pemerintah dalam menjalankan Perda nomor 20 tahun 2016 tentang pedoman penataan dan pembinaan pasar tradisional, pusat pembelanjaan dan toko modern di Kabupaten Karawang.
Penelitian ini dilakukan dengan subyek pedagang pada pasar tradisional di Kabupaten Karawang. Penelitian ini termasuk penelitian deskriptif kuantitatif. Variabel dalam penelitian ini adalah keberadaan pasar modern dan pedagang pasar tradisional. Populasi dalam penelitian ini adalah pelaku usaha pedagang pasar tradisional di Kabupaten Karawang. Teknik pengumpulan data menggunakan angket, wawancara, dan dokumentasi. Teknik analisis data yang digunakan adalah (1) Analisis kuantitatif menggunakan persentase (%), rerata atau mean (M), dan penghitungan Mean Ideal ( Mᵢ ). (2) Analisis kualitatif dilakukan melalui tiga komponen berurutan, yaitu reduksi data (data reduction), penyajian data (data display), dan penarikan kesimpulan (conclusion drawing).
Hasil penelitian menunjukkan bahwa (1) Kebijakan yang berkaitan dengan pasar modern dan pasar tradisional yaitu Peraturan Presiden Republik Indonesia Nomor 112 Tahun 2007, Peraturan Menteri Dalam Negeri Republik Indonesia Nomor 20 Tahun 2012, Peraturan Menteri Perdagangan Republik Indonesia Nomor:70/M-DAG/PER/12/2013. Pemerintah Kabupaten Karawang pun telah mengeluarkan Peraturan Daerah Nomor 20 Tahun 2016 tentang Penataan dan Pembinaan Pasar Rakyat, Pusat Perbelanjaan dan Toko Swalayan.(2) Dampak adanya pasar modern terhadap pasar tradisional dilihat dari segi omset yang mengalami penurunan omset, penurunan pendapatan dan jumlah pelanggan mengalami penurunan yang cukup besar. (3) Upaya yang dilakukan Pemerintah dalam menjalankan Peraturan Daerah Nomor 20 Tahun 2016 masih minim.

Kata Kunci: Dampak, Pasar Modern, Pasar Tradisional.
The Use of Tocilizumab in Combination with Methotrexate in Indonesian Rheumatoid Arthritis Patients (PICTURE INA Study)
Authors: Setyohadi Bambang , Isbagio Harry , Wachjudi Rachmat Gunadi , Soeroso Joewono , Kalim Handono , Achadiono Deddy Nur Wachid 
Published: May 2020

Background Aim of this research is to assess the efficacy and safety of tocilizumab (TCZ) in combination with methotrexate (MTX) in Indonesian patients with moderate to severe active rheumatoid arthritis (RA) who have an inadequate response to non-biologic DMARDs.Methods This was a interventional, prospective, single arm, multicenter, study in Indonesian male or female patients aged ≥ 18 years old, with a diagnosis of RA for > 6 months based on ACR 1987 revised criteria with moderate to severe disease activity (DAS28 score > 3.2) after ≥ 12 weeks of non-biologic DMARDs treatment. The treatment consisted of tocilizumab, 8 mg/kg, intravenous (IV), every 4 weeks for a total of 6 infusion in combination with oral MTX (10−25 mg) every week. Efficacy was assessed based on the percentage of patients achieving low disease activity state (DAS28 < 3.2), percentage of patients achieving reduction > 1.2 point of DAS28, percentage of patients achieving remission (DAS28 < 2.6), and percentage of patients with ACR20, ACR50, and ACR70 responses. Descriptive statistics will be used for presentation of results.Results 100% patients reached low disease activity (DAS28 ≤ 3.2) at last study visit (week 24) and clinically significant improvement (reduction at least 1.2 units) at every visit in DAS28, both for ITT or PP patients. Remission (DAS28 < 2.6) was observed in 82.1% (ITT patients) and 93.1 % (PP patients) on last study visit. ACR20, ACR50, and ACR70 were achieved in 20%, 34%, and 34% (ITT patients), and 7%, 24%, and 62% (PP patients) on week 24. There were 3 out of 39 patients (7.69%) with adverse events (AE) and serious adverse events (SAE) that resulted in discontinuation of TCZ treatment, consisting of 1 patient with SAE of sepsis ec acquired community pneumonia, 1 patient with SAE of pneumonia tuberculosis, and 1 patient with AE of candidiasis. Most common adverse events were hepatic dysfunction (30.7%), hypercholesterolemia (23.1%), followed by arthralgia (20.5%) Twelve percent of patients needed dose modification due to elevated liver enzyme (elevated ALT/SGPT level).Conclusion Tocilizumab seems to be efficacious and likely to have good safety profile in non- biologic DMARD nonresponsive RA patients of PICTURE INA study. Keywords: Rheumatoid Arthritis, Tocilizumab, DMARD, DAS28
Correlation of sCD40L Level with Force Vital Capacity Value in Restrictive Lung Disease of Systemic Sclerosis Patients
Authors: Salim Susanto , Wachjudi Rachmat Gunadi , Dewi Sumartini 
Published: May 2020

Background: Interstitial Lung Disease (ILD) is one of the major cause of morbidity and mortality in Systemic Sclerosis (SSc). The gold standard to diagnose ILD is using High Resolution Computed Tomography (HRCT) scan. HRCT scan need a lot of cost and not always available, so another diagnosing test is needed as an alternative modality to diagnose ILD. ILD is a restrictive lung disease caused by lung fibrosis which is proved by the decrease of Forced Vital Capacity (FVC) in spirometry, and followed by the increase of soluble CD40L (sCD40L) level in plasma. This sCD40L may become a potential biomarker to evaluate lung fibrosis in SSc patients. The aim of this study is to analyze the correlation of sCD40L levels with FVC score in SSc patients with restrictive lung disease.Method:This cross sectional study was enrolled by the SSc patient who has restrictive lung disease based on spirometry test, at Rheumatology outpatient clinic dr. Hasan Sadikin Hospital from May 2015 to May 2016. All subject took underwent history, physical examination, spirometry and blood test for sCD40L. Data were analyzed using Pearson correlation.Result:There were 38 subjects involved in this study, dominated bywoman (92.1%) with mean age 41(±11) years. Subjects consist of 22(57,9%) with limited SSc, 16(42,1%) with diffuse SSc patients and 33 subjects treated with DMARD. Mean sCD40L serum in this study was 6.690,3(±2.377,3) pg/mL, with no statistical difference between limited and diffuse type (p=0.154). Mean FVC score in this study was 58.2(±10,8). There was no significant correlation between sCD40L serum with FVC (r=0.058; p=0.366). There was weak correlation on DMARD naïve subject between sCD40L serum and FVC (r=0.058; p=0.366) but statistically insignificant. There was no significant correlation between sCD40L serum with mRSS (r=0,066; p=0,346).Conclusion: This study founds no correlation between sCD40L with FVC in SSc at dr. Hasan Sadikin Hospital. Keyword : sCD40L, Forced Vital Capacity, Restrictive Lung Disease, Systemic Sclerosis
Mean Platelet Volume on Systemic Lupus Erythematosus Patients with and without Thrombocytopenia in Dr Hasan Sadikin Hospital Bandung: A Descriptive Study
Authors: Philo Patrick , Hamijoyo Laniyati , Turbawaty Dewi Kartika 
Published: May 2020

Abstract
Background : The aim of the study is to provide an insight about mean platelet volume (MPV) value in systemic lupus erythematosus (SLE) with and without thrombocytopenia patient. MPV wa expected to be used to determine the cause thrombocytopenia in lupus, so the patient could be treated appropriately.

Method : The study design was descriptive categoric, and the data were obtained by using cross-sectional method from patient’s medical record and lab examination result in the period from January 1st 2016 – January 31st 2018. The sampling method are done using total sampling. The inclusion criteria of this study were SLE patients which MPV and platelet count had been examined at the same time, the data used is data that was first discovered in the period of the study. The exclusion criteria were incomplete medical record data, patient with thrombocytosis, and SLE with comorbidity such as thrombotic disease (ischemic stroke and deep vein thrombosis), other high inflammatory overlap diseases (such as rheumatoid arthritis and inflammatory bowel disease), and infection.

Result : From 75 patients that match with the inclusion criteria, all patients were female and based on the age of diagnosis, most patients were in age group of 25-34 years old (41,33%). Based on the lab results, group with normal platelet count have 53 data of normal MPV and 12 data of high MPV, while group with thrombocytopenia have 6 data of normal MPV and 4 data of high MPV.

Conclusion : Group with normal MPV value and normal platelet count has the largest proportion, while the group with thrombocytopenia in lupus and high MPV value has the lowest proportion.
Randomized Controlled Trial of Herbal Extracts (Eugenia polyantha, Apium graveolens, Nigella sativa) and Allopurinol Effect on Serum Uric Acid, Urinary Uric Acid and High Sensitivity C-Reactive Protein Levels in Subject with Hyperuricemia
Authors: Sutoko Bantar , Hellmi Rakhma Yanti , W Ika Vemillia , L Stepanus Agung 
Published: May 2020

Background: Eugenia polyantha, Apium graveolens, and Nigella sativa are extracts which in preclinical trial can reduce uric acid serum, increase urinary uric acid excretion. Allopurinol is an inhibitor of the xanthine oxidase enzyme which can also reduce the increase of hsCRP in subjetcs with hyperuricemia.

Objective: To determine the safety and effect of herbal extracts in reducing serum uric acid, increasing uric acid excretion and reducing hsCRP levels in patients with hyperuricemia compared with allopurinol.

Method: This study was a double blind randomized controlled trial (RCT). The subjects were hyperuricemic patients aged ³18 years. The subject was divided into groups that received 3000 mg/day of herbal extracts and allopurinol 100 mg/day for 4 weeks. Evaluation of serum uric acid and urinary uric acid urine were every week, and hsCRP levels was baseline and end of intervention. Other parameters related to the safety of use were examined every 2 weeks.

Results: A number of 44 hyperucemia subjects, 23 subjects received herbal extracts and 21 subjects received allopurinol. The decrease of uric acid serum levels in the herbal extract group was 0,467±1,123;0,600;-2,70-3,00 (p=0.027), while in the allopurinol group 1,11
4±0,813;1,30;-1,30-2,30 (p=0,000). Uric acid excretion in the herbal extract group decrease 71,00±1,970;5,50;-92,00-702,00 (p=0,269) and in the allopurinol group decrease 64,54±1,298;22,00;-29,00-440,0 (p=0.003). The reduction of hsCRP in the herbal extract group was 0.08±0.639; 0.01; -1.55-2.05 (p=0.658), and the allopurinol group was -0.33 ± 0.806; -0.01; -2.73- 0.31 (p=0.256).

Conclusion: Herbal extracts (Eugenia poliantha, Apium graveolens and Nigella sativa) and allopurinol can reduce serum uric acid levels in patients with hyperuricemia. Allopurinol also can reduce urinary uric acid excretion.
Prevalence of Carotid Artery Atherosclerosis Plaque in Systemic Lupus Erythematosus in Hasan Sadikin Hospital Bandung in 2017-2018
Authors: Rasyid Irham , Hidayat Syarief , Hamijoyo Laniyati 
Published: May 2020

Background. Systemic Lupus Erythematosus (SLE) is an autoimmune disease involving many organs including the cardiovascular system such as accelerated atherosclerosis or premature atherosclerosis. Atherosclerotic plaque can cause coronary heart disease, ischemic stroke and peripheral arterial disease, which are the main causes of death in the world. The purpose of this study was to determine the prevalence of carotid artery atherosclerosis plaques in patients with SLE.
Method. This research is a descriptive study with a cross-sectional design. Carotid artery atherosclerosis plaques in SLE patients were assessed by analysing results of carotid ultrasound examinations that were conducted in 2017-2018. The inclusion criteria of this study were SLE patients who had undergone carotid doppler ultrasound B mode examination on the carotid artery for the period of 2017-2018. The exclusion criteria in this study were SLE patients with a history of stroke, peripheral arterial disease, and significant coronary artery disease.
Result. This study involved 88 SLE patients who met the inclusion criteria. Results showed that there were 10 SLE patients (11.4%) who had atherosclerotic plaques. SLE patients with atherosclerosis plaque were mostly in the age range of 35-44 years (16%) and 45-54 years (22.2%). There were 2 patients (15.3%) with atherosclerotic plaque from a total of 11 patients had high triglyceride levels (≥150 mg/dL). Chi square analysis of lipid profiles (cholesterol, LDL, HDL, triglycerides) in patients with atheroclerotic plaque revealed not significant (p>0.05). These findings could be caused by several factors, such as the small number of samples in this study and the non-traditional factors in the formation of atherosclerotic plaque as well as other traditional factors
Conclusion. The prevalence of carotid artery atherosclerosis plaques in patients with SLE in Dr. Hasan Sadikin General Hospital in 2017-2018 is 11.4%.
Lupus Low Disease Activity State Associated with Lower Fatigue
Authors: Saputro Ryan Ardian , Andayani Santi , Usman Stefanie Yuliana , Hamijoyo Laniyati 
Published: May 2020

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with heterogeneous clinical manifestations including fatigue. Previous studies aimed at proving the relationship between fatigue and SLE disease activity showed conflicting results. In 2015, Asia Pacific Lupus Collaboration (APLC) developed low disease activity criteria, named Lupus Low Disease Activity State (LLDAS). Patients who spend more time in LLDAS have significantly lower morbidity. This study aimed to evaluate the association between disease activity based on LLDAS and fatigue.
Methods: This is a analytical cross-sectional study. Subjects were SLE patients at rheumatology clinic in Dr. Hasan Sadikin Hospital, Bandung during June-January 2018. Subjects were evaluated based on LLDAS criteria and divided into 2 groups: LLDAS and non-LLDAS. Fatigue status of the subjects was assessed with Fatigue Severity Scale (FSS).
Results: A hundred and thirty-three subjects were included in this study, divided into 63 subjects in LLDAS group and 60 subjects in non-LLDAS group. Nineteen subjects (30.2%) in LLDAS group had fatigue and 39 subjects (65%) in non-LLDAS had fatigue. There was a significant association between LLDAS and fatigue (p< 0.001). Nonetheless, fatigue level in LLDAS group was still high since disease activity was not the only factor related to fatigue. Fatigue may be a distinct clinical manifestation of neuropsychiatric lupus and may be independent of lupus disease activity
Conclusions: There was a significant association between LLDAS and fatigue showed by lower fatigue level was found in the LLDAS group than in the non-LLDAS group.

Keywords: Systemic lupus erythematosus, disease activity, Lupus Low Disease Activity State, fatigue
KESADARAN MASYARAKAT TERHADAP PERATURAN LALU LINTAS (STUDI PELANGGARAN LALU LINTAS DI APILL SIMPANG EMPAT NGORESAN)
Authors: Aminah Siti 
Published: May 2020

Menurut UU Lalu Lintas dan Angkutan Jalan pasal 287 ayat (1) telah disebutkan bahwa pelanggar APILL akan dipidana kurungan paling lama 2 bulan dan denda paling banyak lima ratus ribu rupiah, namun APILL Simpang Empat Ngoresan malah dianggap tidak ada oleh pengguna jalan. Artikel ini bertujuan untuk mengetahui kesadaran masyarakat terhadap peraturan lalu lintas dengan studi kasus pelanggaran lalu lintas yang terjadi di APILL Simpang Empat Ngoresan, Surakarta. Metode yang digunakan adalah pendekatan kualitatif dengan analisis deskriptif. Analisis data menggunakan data reduction, data display, dan conclusion drawing/verification. Hasil penelitian ini adalah kesadaran hukum masyarakat rendah karena tidak adanya penegak hukum dan kurangnya fasilitas yang mendukung tertib hukum masyarakat.

Kata Kunci: kesadaran hukum, pelanggaran lalu lintas, APILL Simpang Empat Ngoresan
PERLINDUNGAN PRAKTIK KEPERAWATAN DALAM MEWUJUDKAN KEPASTIAN HUKUM DALAM MENINGKATKAN DERAJAT KESEHATAN PASIEN
Authors: Diantama Gilang Dwi 
Published: May 2020

Dalam undang-undang yang dimaksud Keperawatan adalah kegiatan pemberian asuhan kepada individu, kelompok, atau masyarakat, baik dalam keadaan sakit maupun sehat. Sedangkan Perawat adalah seseorang yang telah lulus pendidikan tinggi keperawatan, baik di dalam maupun di luar negeri yang diakui oleh pemerintah sesuai dengan ketentuan Peraturan Perundang-undangan. Di Indonesia sekitar 60% tenaga kesehatan merupakan perawat. Banyaknya jumlah perawat di Indonesia ini turut mempengaruhi layanan kesehatan masyarakat, dan ini diperhatikan dalam undang-undang. Perawat sangat mempengaruhi kualitas pelayanan kesehatan selain itu perawat perlu mempraktikan ilmunya secara otonom sehingga ada kejelasan atas kewenangan dan batas tangung jawab dalam melakukan pelayanan kesehatan, undang-undang keperawatan yang telah disahkan oleh pemerintah dapat memberi kepastian dan jaminan hukum bagi tenaga kesehatan khususnya perawat dalam melaksanakan pelayanan keperawatan, selain juga dapat menjadi kepastian dan jaminan hukum bagi pasien (masyarakat) yang akan memanfaatkan pelayanan keperawatan. Dengan adanya undang-undang ini diharapkan dapat meningkatkan aksesibilitas, dan mutu pelayanan keperawatan, serta dapat meningkatkan derajat kesehatan masyarakat yang merujuk kepada Standar Praktik Keperawatan. Pelaksanaan Standar Praktik Keperawatan yang dilaksanakan dan dipatuhi seperti yang diatur dalam Undang-undang Keperawatan memberikan kepastian hukum bagi perawat maupun pasien dalam mendapatkan pelayanan keperawatan yang prima sehingga dapat terjadi peningkatan derajat kesehatan.

Kata Kunci : Keperawatan, Kepastian Hukum, Peningkatan derajat Kesehatan
Cedevole al tatto // To Be in Any Form // Ser en cualquier forma
Authors: Loreto Paola Maria 
Published: May 2020

La silloge è stata ispirata dall’osservazione e dall’ascolto, ricettivi, degli elementi della natura in ambiente montano, alpino, che potrebbe essere quello “di casa”, le Prealpi Orobie, ma anche qualsiasi altro luogo di montagna frequentato dall’autrice. Esprime il senso di un’appartenenza profonda, ineludibile, pacificante a un mondo di relazioni eque, oggettive, multidirezionali.

The poems were inspired by the keenly receptive observation of natural elements in a mountainous environment - possibly the author’s “home,” the Prealpi Orobie in Italy, but also whatever other mountain landscape she has happened to experience in her hikes and climbing. The triptych expresses the profound sense of an unavoidable and pacifying belonging to a world of even, objective, and multiple relations.

La inspiración para los poemas vino de la observación intensamente receptiva de los elementos naturales en un entorno montañoso (probablemente el "hogar" de la autora, el Prealpi Orobie en Italia, pero también de cualquier otro paisaje de montaña que haya experimentado mientras hacía senderismo y escalada). El tríptico expresa el sentido inevitable y pacificador de pertenecer a un mundo de relaciones regulares, objetivas y múltiples.