bluuebunny/crossref_metadata_2025_split huggingface dataset:
TAKING THE “LEED” IN INDOOR AIR QUALITY: DOES CERTIFICATION RESULT IN HEALTHIER BUILDINGS?
Authors: Phillips Hannah , Handy Rod , Sleeth Darrah , Thiese Matthew S. , Schaefer Camie , Stubbs James 
Published: September 2020

ABSTRACT
Indoor Air Quality (IAQ) has been an area of growing concern with the increasing knowledge of health hazards associated with contaminants, particularly in high occupancy buildings where residents may be exposed to high levels of nuisance dust and other contaminants. Leadership and Energy in Environmental Design (LEED®) certification, which is awarded to buildings that prioritize sustainability and efficient resource use, has been increasingly sought in new construction. As LEED-certified buildings become more commonplace, it is worthwhile to consider whether these new building practices improve IAQ for its occupants. This study compares particulate matter (PM) concentrations in 12 LEED-certified buildings to 12 analogous non-LEED certified buildings on the University of Utah campus. Real-time air sampling was conducted in each building for PM measurements and a Wilcoxon signed rank test was conducted to compare PM levels. A statistically significant difference was found between LEED certification and PM concentrations, with LEED-certified buildings containing, on average, approximately half the PM of their non-LEED counterparts. These findings suggest that LEED certification is worth the financial investment, as it may lead to improved IAQ for residents. However, further research on other contaminants is warranted, including the characterization and comparison of formaldehyde and carbon dioxide levels.
Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses
Authors: Li Wenjing , Shi Lei , Zhuang Zhenpeng , Wu Han , Lian Meng , Chen Yihui , Li Lei , Ge Weikai , Jin Qin , Zhang Quanjun , Zhao Yu , Liu Zhaoming , Ouyang Zhen , Ye Yinghua , Li Yingying , Wang Hai , Liao Yuan , Quan Longquan , Xiao Lei , Lai Liangxue , Meng Guangxun , Wang Kepin 
Published: September 2020

Abstract
The NLRP3 inflammasome is associated with a variety of human diseases, including cryopyrin-associated periodic syndrome (CAPS). CAPS is a dominantly inherited disease with NLRP3 missense mutations. Currently, most studies on the NLRP3-inflammasome have been performed with mice, but the activation patterns and the signaling pathways of the mouse NLRP3 inflammasome are not always identical with those in humans. The NLRP3 inflammasome activation in pigs is similar to that in humans. Therefore, pigs with precise NLRP3-point mutations may model human CAPS more accurately. In this study, an NLRP3 gain-of-function pig model carrying a homozygous R259W mutation was generated by combining CRISPR/Cpf1-mediated somatic cell genome editing with nuclear transfer. The newborn NLRP3 R259W homozygous piglets showed early mortality, poor growth, and spontaneous systemic inflammation symptoms, including skin lesion, joint inflammation, severe contracture, and inflammation-mediated multiorgan failure. Severe myocardial fibrosis was also observed. The tissues of inflamed skins and several organs showed significantly increased expressions of NLRP3, Caspase-1, and inflammation-associated cytokines and factors (i.e., IL-1β, TNF-α, IL-6, and IL-17). Notably, approximately half of the homozygous piglets grew up to adulthood and even gave birth to offspring. Although the F1 heterozygous piglets showed improved survival rate and normal weight gain, 39.1% (nine out of 23) of the piglets died early and exhibited spontaneous systemic inflammation symptoms. In addition, similar to homozygotes, adult heterozygotes showed increased delayed hypersensitivity response. Thus, the NLRP3 R259W pigs are similar to human CAPS and can serve as an ideal animal model to bridge the gap between rodents and humans.
TL1A Promotes Lung Tissue Fibrosis and Airway Remodeling
Authors: Herro Rana , Miki Haruka , Sethi Gurupreet S. , Mills David , Mehta Amit Kumar , Nguyen Xinh-Xinh , Feghali-Bostwick Carol , Miller Marina , Broide David H. , Soloff Rachel , Croft Michael 
Published: September 2020

Abstract
Lung fibrosis and tissue remodeling are features of chronic diseases such as severe asthma, idiopathic pulmonary fibrosis, and systemic sclerosis. However, fibrosis-targeted therapies are currently limited. We demonstrate in mouse models of allergen- and bleomycin-driven airway inflammation that neutralization of the TNF family cytokine TL1A through Ab blocking or genetic deletion of its receptor DR3 restricted increases in peribronchial smooth muscle mass and accumulation of lung collagen, primary features of remodeling. TL1A was found as a soluble molecule in the airways and expressed on the surface of alveolar macrophages, dendritic cells, innate lymphoid type 2 cells, and subpopulations of lung structural cells. DR3 was found on CD4 T cells, innate lymphoid type 2 cells, macrophages, fibroblasts, and some epithelial cells. Suggesting in part a direct activity on lung structural cells, administration of recombinant TL1A into the naive mouse airways drove remodeling in the absence of other inflammatory stimuli, innate lymphoid cells, and adaptive immunity. Correspondingly, human lung fibroblasts and bronchial epithelial cells were found to express DR3 and responded to TL1A by proliferating and/or producing fibrotic molecules such as collagen and periostin. Reagents that disrupt the interaction of TL1A with DR3 then have the potential to prevent deregulated tissue cell activity in lung diseases that involve fibrosis and remodeling.
Immune Response Resetting as a Novel Strategy to Overcome SARS-CoV-2–Induced Cytokine Storm
Authors: Nowill Alexandre E. , de Campos-Lima Pedro O. 
Published: September 2020

AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which rapidly became a pandemic of global proportions. Sepsis is commonly present with high lethality in the severe forms of the disease. The virus-induced cytokine storm puts the immune system in overdrive at the expense of the pathogen-specific immune response and is likely to underlie the most advanced COVID-19 clinical features, including sepsis-related multiple organ dysfunction as well as the pathophysiological changes found in the lungs. We review the major therapeutic strategies that have been considered for sepsis and might be amenable to repurposing for COVID-19. We also discuss two different immunization strategies that have the potential to confer antiviral heterologous protection: innate-induced trained immunity and adaptive-induced immune response resetting.
Fourier coefficients of minimal and next-to-minimal automorphic representations of simply-laced groups
Authors: Gourevitch Dmitry , Gustafsson Henrik P. A. , Kleinschmidt Axel , Persson Daniel , Sahi Siddhartha 
Published: September 2020

AbstractIn this paper, we analyze Fourier coefficients of automorphic forms on a finite cover G of an adelic split simply-laced group. Let
$\pi $
be a minimal or next-to-minimal automorphic representation of G. We prove that any
$\eta \in \pi $
is completely determined by its Whittaker coefficients with respect to (possibly degenerate) characters of the unipotent radical of a fixed Borel subgroup, analogously to the Piatetski-Shapiro–Shalika formula for cusp forms on
$\operatorname {GL}_n$
. We also derive explicit formulas expressing the form, as well as all its maximal parabolic Fourier coefficient, in terms of these Whittaker coefficients. A consequence of our results is the nonexistence of cusp forms in the minimal and next-to-minimal automorphic spectrum. We provide detailed examples for G of type
$D_5$
and
$E_8$
with a view toward applications to scattering amplitudes in string theory.
Performance of Mulching to the Stimulation on the Growth of Cucumber (Cucumis Sativus) Production
Authors: Akter Daliya , Islam Mohammad Shafiqul , Ruhi Roksana Aftab , Joy Md Istiak Hossain , Trina Fariha Ahmed 
Published: September 2020

A field experiment was conducted at Noakhali ,Chittagong during the season in 2019, to determine the effect of mulching on cucumber (Cucumis sativus) production where Alavy Green variety was used. The study was laid out in RCBD (Randomized complete block design) method having three replications. The treatment used in this study consists of T1=Black plastic mulching, T2=Water hyacinth mulching, T3=Rice straw mulching, Control= no mulching. The plant showed significant differences after application of various treatments. The maximum average length of vine (113 cm), number of branch per plant (8.33), number of leaves per plant (28.44), number of tendrils per plant (11.52), number of flowers per plant (16.33), number of fruits per plant (9), length of fruit (18 cm), weight of individual fruit (239.67 g) were obtained from T1 treatment (Black plastic mulching) .On the other hand, minimum average length of vine (103.91 cm), number of branch per plant (4.33), number of leaves per plant (22.67), number of tendrils per plant (7.33), number of flowers per plant (12.33), number of fruits per plant (4.33), length of fruit (9 cm), weight of individual fruit (173.67 g) were obtained from T0 control (No mulching). Among organic (Water hyacinth and Rice straw) and inorganic mulches (Black plastic), inorganic mulches gave better performance over organic mulches.
Atributos químicos e metais pesados em solos de remanescentes florestais urbanos
Authors: Longo Regina Marcia , Ferreira Denise Helena Lombardo , Silva Alessandra Leite da , Penereiro Júlio César , Regina Mendes Deborah 
Published: September 2020

Apesar de legislações que promovem a proteção de determinadas áreas relevantes, como as unidades de conservação, a borda destas encontra-se altamente sujeita aos efeitos externos, conhecido como efeito de borda. Este fenômeno se manifesta pela alteração das características da vegetação, da fauna e do solo nesta área. Diante disso, o objetivo deste trabalho foi quantificar aspectos da fertilidade do solo e dos metais pesados: chumbo (Pb), cromo (Cr) e níquel (Ni) que possam estar presentes no solo nas bordas da Mata de Santa Genebra, Campinas/SP, Brasil, a fim de verificar a interferência dos diferentes graus de uso e ocupação do entorno. Realizaram-se coletas de amostras de solo em 40 pontos da borda do fragmento, equidistantes em 200 m, e procederam-se análises químicas de fertilidade e de metais pesados. Nas amostras foram determinados os teores de: pH (CaCl2); matéria orgânica (MO); fósforo (P), potássio (K), cálcio (Ca) e magnésio (Mg). Os valores da capacidade de troca de cátions (T) e da saturação por bases (V%) foram obtidos por meio de cálculos. Nas leituras das amostras para a determinação quantitativa dos metais: chumbo (Pb), cromo (Cr) e níquel (Ni) foi utilizada a Espectrofotometria de Absorção Atômica (EAA) por atomização em chama. Após análise dos resultados obtidos pode-se observar que o remanescente em estudo apresenta condições de conservação em relação à fertilidade natural do solo que pode vir a auxiliar nos programas de reflorestamento. No entanto, algumas regiões do entorno, principalmente aquelas que se encontram sob pressões externas (urbanização, presença de estradas e atividades rurais), apresentaram alterações nos teores de metais pesados em estudo.
PENGETAHUAN PETERNAK TENTANG ESTRUS PADA SAPI ACEH DENGAN TERJADINYA REPEAT BREEDING DI KABUPATEN PIDIE
Authors: Dasrul, Mustafa Sabri Djoko Subagyo, Tongku N Siregar, Teuku Reza Ferasyi 
Published: September 2020

The study was aimed to determine the level of knowledge of farmers about cattle estrus Aceh with the occurrence of repeat breeding in Pidie District. Samples were obtained from secondary data reports for animal husbandry Department aceh Pidie 161 female cows study was. Carried out in the form of observational study with cross sectional approach. Primary data were collected by direct observation and interviews with questionnaires to farmers and inseminator. The data were analyzed descriptively. Chi Square test (X2) was used to determine the association between factors that cause, while Odds Ratio (OR) was used to calculate the strength of the association. The results of this study which has gained significantly associated (P less-than 0.05) on the incidence of repeat breeding is knowledge estrus with OR = 2.3. And the conclusion is. knowledge estrus against Aceh cattle repeat breeding associated with the occurrence of repeat positive or are associated. Keywords: knowledge estrus, repeat breeding, cattle Aceh
KEANEKARAGAMAN JENIS TANAMAN OBAT DI KECAMATAN PEUKAN BARO KABUPATEN PIDIE
Authors: Zufahmi Zufahmi 
Published: September 2020

Kecamatan Peukan Baro merupakan salah satu kecamatan yang terdapat di Kabupaten Pidie, Aceh. Kecamatan ini dinilai berpotensi memiliki keanekaragaman jenis tumbuhan obat. Penelitian ini bertujuan untuk mengetahui tingkat keanekaragaman jenis tanaman obat di Kecamatan Peukan Baro Kabupaten Pidie. Penelitian ini dilaksanakan di 14 desa yang berada di Kecamatan Peukan Baro. Teknik pengumpulan data dilakukan dengan wawancara, pengamatan langsung serta dokumentasi tanaman. Teknik analisis data menggunakan teknik kuantitatif yang selanjutnya dikaji menggunakan rumus Shannon-Wienner. Hasil Penelitian ditemukan 31 jenis tanaman obat yang terdiri dari 21 famili. Keanekaragaman jenis tanaman obat di Kecamatan Peukan Baro tergolong tinggi dengan nilai indeks 3,2169. Jenis tanaman obat terbanyak berasal dari famili Zingiberaceae. Bagian yang paling banyak digunakan sebagai obat adalah daun.Â Kata Kunci: Keanekaragaman, Shannon- Wienner, Tanaman obat
ANALISIS PEMBERDAYAAN PETANI BAWANG MERAH MELALUI PMUK (PENGUATAN MODAL USAHA KELOMPOK) DI DESA CEUROCOK SAGOE KECAMATAN SIMPANG TIGA KABUPATEN PIDIE
Authors: Nurul Samiah Cut Risma Aini, 
Published: September 2020

Penelitian ini bertujuan menganalisis kegiatan pemberdayaan petani melalui program PUMK (Penguatan Modal Usaha Kelompok) dan peranannya terhadap peningkatan pendapan petani melalui program PUMK (Penguatan Modal Usaha Kelompok) di Ceurucok Sagoe Keamatan Simpang Tiga Kabupaten Pidie. Penelitian dilakukan pada bulan anuari 2017. Populasi penelitian adalah seluruh petani yang terlibat dalam kegiatan pemberdayaan petani Bawang Merah melalui PUMK (Penguatan Modal Usaha Kelompok) yang berumlah 180 Petani, sampel yang diambil sebanyak 36 Petani. Metode analisis data mengunakan regresi linear sederhana.Program PMUK mempunyai pengaruh signifikan terhadap pemberdayaan petani Bawang Merah di Desa Ceurucok Sagoe Kecamatan Simpang Tiga Kabupaten Pidie dengan koefisien variabl sebesar 0,964 atau pelaksanaan program PUMK sebesar satuan akan meningkatkan pemberdayaan petani sebesar 0,964 satuan. Koefisien determinasi sebesar 0,528 menunjukkan variable PMUK dapt menelaskan variable pemberdayaan petani sebesar 52,80 %. Nilai t hitung > t tabel (6,17 > ,028) dengan (tingkat kepercayaan 95 %), artinya variable PMUK mempunyai pengaruh yang siginifikan terhadap peningkatan pemberdayaan petani Bawang Merah di Desa Ceurucok Sagoe Kecamatan Simpang Tiga Kabupaten PidieKata Kunci : Analisis, Pemberdayaan, Petani, Bawang Merah, PUMK (Penguatan Modal Usaha Kelompok)
PENGARUH PEMBERIAN UNSUR HARA MIKRO BORON TERHADAP PERTUMBUHAN DAN PRODUKSI BAWANG MERAH (Allium Cepa, L.)
Authors: Bakhtiar Helmi 
Published: September 2020

The objectives of this research isto study the effect of the boron fertilizer to growth and yieldof onion. The implementation of experiements was conducted to see the respon of the onion by boron fertilizing doses (0-12kg/ha), the research has been conducted at Meunasah Lhee Village, Kecamatan Simpang Tiga, District of Pidie at Gadu Season (July to October) 2018. The result shows that boron affects the growth and yield of the onion. Boron fertilizing with the dose 6 kg/ha results the optimal growth, 15,13 cloves per clump, and the highest yield, which ic 25,20 ton/ha fresh cloves and 22,83 ton/ha dry cloves. Onion is a very strategic commodity. Beside has high economic value, among very kind vegetables it contributes inflation because the price is fluctuative dan the demand is raised from time to time. The onion yield is low at the farmer level, one of the reasons is fertilizer which not properly given. One the micro nutrients needed by plant is boron (B).Keywords:Â micro fertilizer, boron, productivity, onion
PROSPEK PENGEMBANGAN HOME INDUSTRI MINYAK NILAM DI GAMPONG PUCOK DRIEN KECAMATAN PANGA KABUPATEN ACEH JAYA
Authors: Zahriani Julia, Al Asri Abubakar, 
Published: September 2020

Penelitian ini bertujuan untuk mengetahui prospek pengembangan home industri budidaya minyak nilam di Gampong Pucok Drien Kecamatan Panga Kabupaten Aceh Jaya. Metode yang digunakan dalam penelitian ini menggunakan metode analisis kuantitatif dan analisis kualitatif. Hasil penelitian menunjukkan bahwa Gampong Pucok Drien Kecamatan Panga Kabupaten Aceh Jaya memiliki prospek yang sangat bagus untuk pengembangan budidaya nilam dikarenakan beberapa aspek yang sangat mendukung seperti aspek pasar, aspek teknis, aspek lingkungan serta sosial dan ekonomi. Tanaman mudah dibudidayakan dan harga mahal dan merupakan komoditi ekspor. Saluran pemasaran minyak nilam di Gampong Pucok Drien Kecamatan Panga Kabupaten Aceh Jaya sudah efesien karena menggunakan saluran pemasaran yang pendek yaitu produsen – pengumpul – konsumen.Kata Kunci : Prospek Pengembangan, Usahatani Minyak Nilam
PENGARUH PEMBERIAN PUPUK GUANO DAN PUPUK GROWMORE TERHADAP PERTUMBUHAN BIBIT KOPI ROBUSTA (Coffea robusta L.)
Authors: Muksalmina Karnilawati, Rudi Fadhli, 
Published: September 2020

Usaha kopi organik dapat dijadikan sebagai salah satu alternatif dalam meningkatkan mutu kopi robusta di Indonesia. Penelitian ini bertujuan untuk mengetahui pemberian pupuk guano dan growmore terhadap pertumbuhan bibit kopi robusta. Penelitian dilaksanakan di Kebun Percobaan Fakultas Pertanian Universitas Jabal Ghafur Glee Gapui Sigli mulai Februari sampai April 2017. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) pola faktorial 4x3 dengan 3 ulangan. Faktor pertama pupuk guano terdiri dari 4 taraf yaitu 1 bagian pupuk guano dengan 2 bagian tanah (1:2), 1 bagian pupuk guano dengan 3 bagian tanah (1:3), 1 bagian pupuk guano dengan 4 bagian tanah (1:4) dan 1 bagian pupuk guano dengan 5 bagian tanah (1:5). Faktor kedua konsentrasi growmore terdiri dari 3 taraf yaitu 1 gr/liter air, 2 gr/liter air dan 3 gr/liter air. Hasil Penelitian menunjukkan bahwa pupuk guano berpengaruh nyata terhadap jumlah helai daun dan panjang akar. Pemberian konsentrasi growmore berpengaruh nyata tehadap jumlah helai daun. Adanya interaksi nyata antara pupuk guano dan konsentrasi growmore terhadap diameter pangkal batang 90 HST.Kata Kunci : Guano, growmore, kopi robusta
KEANEKARAGAMAN JENIS TUMBUHAN PEKARANGAN YANG TERDAPAT DI KEMUKIMAN LUENG PUTU KECAMATAN BANDAR BARU KABUPATEN PIDIE JAYA
Authors: Maulinda Zufahmi, Ervina Dewi, 
Published: September 2020

Penelitian ini berjudul ”Keanekaragaman Jenis Tumbuhan Pekarangan yang terdapat di Kemukiman Lueng Putu Kecamatan Bandar Baru Kabupaten Pidie Jaya”, penelitian ini bertujuan untuk mengetahui keanekaragaman jenis tumbuhan pekarangan di kemukiman Lueng Putu. Penelitian ini menggunakan metode survey Eksploratif dengan metode Simple random sampling. Analisis data ditentukan dengan Indeks Keanekaragaman. Hasil penelitian menunjukkan terdapat 79 jenis tumbuhan yang termasuk kedalam 34 Famili. Indeks keanekaragaman jenis tumbuhan pekarangan yang ditemukan di Kemukiman Lueng Putu tergolong kriteria tinggi yaitu H’=3,465.Kata kunci: Keanekaragaman, Tumbuhan, Pekarangan
KAJIAN PREVALENSI REPEAT BREEDING PADA SAPI ACEH DI KABUPATEN PIDIE SEBAGAI UPAYA UNTUK PEMENUHAN KEBUTUHAN PANGAN
Authors: Sri Rahayu Djoko Subagyo, 
Published: September 2020

Tujuan penelitian ini adalah untuk mengetahui prevalensi repeat breeding pada sapi aceh di Kabupaten Pidie sebagai upaya untuk pemenuhan kebutuhan pangan. Sampel diperoleh dari data sekunder laporan Dinas Peternakan Kabupaten Pidie 161 ekor sapi aceh betina. Dilakukan dalam bentuk study observasi dengan pendekatan cross sectional. Pengumpulan dataprimer dilakukan dengan pengamatanlangsung dan wawancara melalui kuisioner terhadap peternak dan inseminator. Data yang di peroleh ditabulasikan, sedangkan untuk melihat prevalensi repeat breeding dianalisis secara deskriptif. Hasil dari penelitian ini didapat prevalensi repeat breeding 58,3 %. Dan kesimpulannya adalah prevalensi repeat breeding sapi aceh di Kabupaten Pidie 58,3 % . Faktor yang menyebabkan adalah manajemen pemeliharaan, pengetahuan peternak dan inseminator. Kata kunci: prevalensi, repeat breeding, Sapi Aceh
MEMBANGUN INTEGRITAS DI SATUAN PENDIDIKAN STRATEGI KEPEMIMPINAN KEPALA SEKOLAH, GURU, ORANG TUA, DAN MASYARAKAT DALAM MEMBENTUK KARAKTER SISWA ( Studi Kasus Di SDN Antara Kecamatan Trienggadeng Kabupaten Pidie Jaya)
Authors: Marsalin Marsalin, 
Published: September 2020

Penelitian ini bertujuan untuk menderskripsikan strategi kepala sekolah, guru, orang tua, dan masyarakat dalam pembentukan karakter siswa di sekolah dasar. Pendekatan penelitian yang diguna- kan adalah kualitatif dengan jenis studi kasus. Instrumen penelitian adalah peneliti sendiri. Pengum- pulan data menggunakan wawancara mendalam, observasi partisipasi dan dokumentasi. Responden penelitian bersifat snow-ball. Teknik analisis data menggunakan model Creswell (2014). Keabsahan data digunakan kriteria kredibilitas, transferabilitas, dependabilitas, dan komfirmabilitas. Kesimpulan penelitian adalah strategi kepala sekolah dalam membentuk karakter siswa dengan filosofis kepemim- pinan, keteladanan, kedisiplinan, kepemimpinan instruksional, kepemimpinan mutu, serta pemberda- yaan guru dan tenaga kependidikan. Strategi guru adalah keteladanan, pembiasaan, dan sentuhan kalbu. Strategi orang tua dan masyarakat adalah komunikasi efektif dan kemitraan efektif. Kata Kunci: strategi, kepala sekolah, guru, masyarakat, karakter
PERAN GURU DALAM PENCEGAHAN PERILAKU KEKERASAN DI SMA NEGERI 2 SEUNAGAN NAGAN RAYA
Authors: Fitria Ricky Dear 
Published: September 2020

The role of the teacher relates to how a teacher is able to understand and determine the limits that must be done in organizing material, interacting and doing the learning process. Violent behavior is the use of force or force with the aim of hurting a weaker person or group, so that the victim feels depressed or traumatized and helpless. This study aims to determine the role of teachers in preventing violent behavior in Sma Negeri 2 Seunagan Nagan Raya. This research is descriptive with cross sectional study approach through total sampling technique. Research data collection was carried out on 11 to 8 December 2019 in SMA 2 Seunagan Nagan with a total of 28 respondents, data collection tools used in the form of a questionnaire scale consisting of 20 question items. Data analysis is presented in the form of a frequency distribution table. The results showed that 64.3% had a teacher's role as a corrector for the prevention of violent behavior in schools, 60.7% had a teacher's role as an informer for the prevention of violent behavior in schools, 78.6% had a teacher's role as a class manager for preventing violent behavior in schools . Based on these data, there is a teacher's role in preventing violent behavior in schools, so the researchers suggest maintaining a good role in providing guidance to students at school. Keywords: Teacher Role, Prevention, Violent Behavior (Bullying)