bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS WACANA KRITIS BAHASA DAN STRATEGI MEDIA SOSIAL CAKRA ABHIPRAYA RESPONSIF DALAM HABITUS
Authors: Kuputri Nadira Maurizka 
Published: November 2020

The pandemic caused by Coronavirus Disease (COVID-19) has an impact on all levels of society in Indonesia. The people who are below the poverty line are no exception. The government's call for physical distancing by stopping many sectors of the economy, further worsening the welfare of the underprivileged. One of non-governmental social organization that was launched on its Instagram page, helping a lot of those in distress, is the Chakra Abhipraya Responsif. In carrying out its activities, the Cakra Abhipraya Responsif is assisted by many parties which makes it easier for them to reach more targets with maximum results. This research tries to look at the communication strategy launched by the Cakra Abhipraya Responsif and their fundraising program through the language they use on their Instagram page. Using Fairclough's critical discourse analysis, the text is analyzed through three components, namely text, discourse practice, and socio-cultural practice. Then by discussing Bourdieu's theory of Habitus and looking far behind the scenes, it can be concluded that social capital in the form of the background/relations of the Cakra Abhipraya Responsif volunteers influences a lot in the implementation of their activities. Although information about social organizations is quite minimal on the internet. The Cakra Abhipraya Responsif communication strategy uses a caption writing style that flicks the audience by focusing their fundraising on communities whose economies have indeed been in decline long before the existence of this pandemic.

Keywords: COVID-19, communication strategy, critical discourse analysis, social capital, habitus
Learning Material Changes as the Impact of the 2013 Curriculum Policy for the Primary School/Madrasah Ibtidaiyah
Authors: Prastowo Andi , Fitriyaningsih Fitriyaningsih 
Published: November 2020

<p class="06IsiAbstrak"> Every curriculum change in Indonesia impacts other components in the national education system, including the learning material. However, main material changes have not been discussed completely. This article presents the analysis result about the impact of 2013 curriculum for Primary School (PS) and Madrasah Ibtidaiyah (MI) in Indonesia on the subject materials. This study used a literature review which examined various applicable 2013 policy documents and textbooks as a representation of the core materials. The findings of this study indicate that the change from the 2006 curriculum to the 2013 curriculum in PS/MI level has an impact on changes in teaching material. The structure and method changes are more structured, hierarchical and not overlap among levels, due to core competencies. The presentation is thematic and from concrete to abstract. Material content also changes. Teaching materials in the 2013 curriculum in PS/MI level are contextual, integrative and focused on character and soft skills. Teaching materials in the 2013 Curriculum also covers critical and creative thinking, communicative, and collaborative learning.</p>
Mortality in Patients with Proximal Femoral Fracture During the COVID-19 Pandemic
Authors: Mamarelis Georgios , Oduoza Uche , Chekuri Ravi , Estfan Rami , Greer Tony 
Published: November 2020

Background:
Coronavirus disease 2019 (COVID-19) is a worldwide pandemic, with a case mortality ratio of approximately 6.4% at the time of writing (May 2020). Mortality increases in elderly patients with comorbidities. Patients with hip fracture have an average age of 80 years, with an estimated 2.8 comorbidities per patient. Evidence is lacking regarding the mortality rate of patients with hip fracture admitted during the COVID-19 pandemic. Our aim was to investigate the mortality rate among patients with a proximal femoral fracture who were admitted to our hospital during the COVID-19 pandemic.

Methods:
We conducted a retrospective review of all patients with a proximal femoral fracture admitted to Southend University Hospital in the U.K. from March to April 2020 (during the COVID-19 pandemic). Data collected included demographics (patient age, body mass index, sex), comorbidities, and blood test values along with COVID-19 diagnosis (based on positive microbiological sample and clinical and radiographic findings) and operative characteristics (time to operation, length of stay, American Society of Anesthesiologists [ASA] classification, Nottingham Hip Fracture Score). The primary outcome was the 30-day mortality rate for patients with a hip fracture who were COVID-19 positive or negative. Kaplan-Meier survival analysis was conducted along with Mann-Whitney U tests and Fisher exact tests.

Results:
Forty-one patients were included in the study, of whom 37 had an available SARS-CoV-2 (severe acute respiratory syndrome-coronavirus 2) swab test result. The overall 30-day mortality was 22%. Eleven patients tested positive for COVID-19. There was a significant difference in the mortality rate between those who tested positive and those who tested negative (54.5% versus 7.69%, respectively; Fisher exact test, p = 0.004) and between the operative patients who tested positive and the operative patients who tested negative (37.5% versus 4.34%, respectively; Fisher exact test, p = 0.043).

Conclusions:
Patients with a proximal femoral fracture may be at higher risk for mortality during the COVID-19 pandemic. We noted that patients with a proximal femoral fracture who tested positive for COVID-19 had a higher 30-day mortality rate compared with those who tested negative. Additional research is required to ascertain the benefits of a reduction in time to operation.

Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
How mHealth can facilitate collaboration in diabetes care: qualitative analysis of co-design workshops
Authors: Bradway Meghan , Morris Rebecca L , Giordanengo Alain , Årsand Eirik 
Published: November 2020

Abstract
Background: Individuals with diabetes are using mobile health (mHealth) to track their self-management. However, individuals can understand even more about their diabetes by sharing these patient-gathered data (PGD) with health professionals. We conducted experience-based co-design (EBCD) workshops, with the aim of gathering end-users’ needs and expectations for a PGD-sharing system. Methods: N=15 participants provided feedback about their experiences and needs in diabetes care and expectations for sharing PGD. The first workshop (2017) included patients with Type 2 Diabetes (T2D) (n=4) and general practitioners (GPs) (n=3). The second workshop (2018) included patients with Type 1 Diabetes (T1D) (n=5), diabetes specialists (n=2) and a nurse. The workshops involved two sessions: separate morning sessions for patients and healthcare providers (HCPs), and afternoon session for all participants. Discussion guides included questions about end-users’ perceptions of mHealth and expectations for a data-sharing system. Activities included brainstorming and designing paper-prototypes. Workshops were audio recorded, transcribed and translated from Norwegian to English. An abductive approach to thematic analysis was taken. Results: Emergent themes were mHealth technologies’ impacts on end-users, and functionalities of a data-sharing system. Within these themes, similarities and differences between those with T1D and T2D, and between HCPs, were revealed. Patients and providers agreed that HCPs could use PGD to provide more concrete self-management recommendations. Participants’ paper-prototypes revealed which data types should be gathered and displayed during consultations, and how this could facilitate shared-decision making. Conclusion: The diverse and differentiated results suggests the need for flexible and tailorable systems that allow patients and providers to review summaries, with the option to explore details, and identify an individual’s challenges, together. Participants’ feedback revealed that both patients and HCPs acknowledge that for mHealth integration to be successful, not only must the technology be validated but feasible changes throughout the healthcare education and practice must be addressed. Only then can both sides be adequately prepared for mHealth data-sharing in diabetes consultations. Subsequently, the design and performance of the joint workshop sessions demonstrated that involving both participant groups together led to efficient and concrete discussions about realistic solutions and limitations of sharing mHealth data in consultations.
County-level Correlates of Dental Service Utilization for Low Income Pregnant Women. Ecologic study of the North Carolina Medicaid for Pregnant Women (MPW) program.
Authors: Moss Mark E , Grodner Andrew , Dasanayake Ananda P. , Beasley Cherry M. 
Published: November 2020

Abstract
Background: Dental care utilization for low income pregnant women is met with challenges in the traditional dentist-centered model of care. County-level measures provide insights for policy and roles for stakeholders that extend beyond the dentist-patient relationship. We examined county-level data to generate hypotheses about factors that influence utilization of dental services in North Carolina’s Medicaid for Pregnant Women (MPW) program.Methods: County-level Medicaid utilization data for dental services for 2014-2016 were pooled to get mean county estimates of dental utilization in the MPW program. Descriptive statistics and multivariate regression models of dental utilization and county-level measures are presented. Data used were collected by NC Child and the Robert Wood Johnson Foundation’s County Health Rankings Reports. USDA Economic Research Service data were used to categorize counties in terms of Farming, Recreation, Persistent Poverty, and metro/non-metro status using Rural Urban Continuum Codes.Results: Dental utilization ranged from 1% to 26% with a median of 8.5% across the 100 counties of North Carolina. Strong patterns linking utilization of dental services in the MPW program to contextual social measures of well-being emerged, specifically, increased reporting of child abuse and neglect, elevated infant mortality, poor quality of life, and worse ranking in years of potential life lost. Counties with persistent poverty had lower rates of dental utilization. Conclusions: Utilization of dental services in the MPW program is generally low. Patterns identify the potential for enhancing community-clinical linkages to improve birth outcomes and care coordination for pregnant women to enhance dental utilization in this population.Dental coverage in the Medicaid program in most states is administered separately from medical coverage. The separation of the funding mechanisms adds a further layer of complexity to care integration. Efforts to enhance dental care for pregnant women in the Medicaid program may benefit from policy that aligns incentives for care coordination within the community. Policy that extends the window of eligibility for dental benefits to 24 months after the birth of the child will help women complete the dental treatment that is needed. This also leverages the value of care coordination for community stakeholders from diverse child health sectors.
Precise Puncture Combined With Simplified Percutaneous Vertebroplasty to Treat Osteoporotic Vertebral Compression Fractures: A Comparative Analysis With Conventional Percutaneous Vertebroplasty
Authors: Pang Ju-tao , Chen Hong , Liu Bin , Zhang Xin-hu 
Published: November 2020

Abstract
ObjectiveThis study aimed to investigate the feasibility and clinical efficacy of precise puncture combined with simplified percutaneous vertebroplasty (PVP) for treating osteoporotic vertebral compression fractures (OVCF).MethodsA total of 82 patients with single-segment osteoporotic vertebral compression fractures (OVCF) were treated with PVP from Dec. 2016 to Nov. 2018. Among the patients, 45 cases in group A and accepted precise puncture combined with simplified PVP, 37 cases in group B and underwent conventional PVP. The operative time, number of intraoperative fluoroscopy, vertebral height restoration, postoperative bone cement distribution and bone cement leakage were observed and compared. The pain relief and improvement of quality of life (QOL) were assessed by visual analog score (VAS) and Oswestry disability index (ODI).ResultsThere were no difference in injected cement volume and hospital stays in group A versus group B (P > 0.05). The operative time, number of intraoperative fluoroscopy and material cost were lower in group A compared with group B (P < 0.05). After surgery, both of the VAS scores and ODI had a significant decrease (P < 0.05). The average vertebral height and Cobb angle were significantly improved (P < 0.05), there was no statistically significant difference between groups at different time points (P > 0.05). The proportion of patients with bone cement dispersion exceeding the midline of vertebra in group A was significantly higher than that in group B (82.2% vs 62.1%) (P < 0.05), whereas the bone cement leakage rate was lower than group B (8.9% vs 27.0%) (P < 0.05). Patients were followed-up for 12-23 months (mean 17.6 months) after surgery, and 3 cases (6.6%) of adjacent vertebral fractures occurred in group A and 2 cases (5.4%) occurred in group B (P > 0.05).Conclusion﻿Precise puncture can improve the accuracy of puncture needle through pedicle to vertebral body. It conducive to obtain a better diffusion of bone cement across the midline with lower bone cement leakage rate. Simplified PVP can reduce the surgery procedures, shorten the operatige time, reduces the X-ray frequency, but also saves material cost.
Effects of Potent Neutralizing Antibodies from Convalescent Plasma in Patients Hospitalized for Severe SARS-CoV-2 Infection.
Authors: Gharbharan Arvind , Jordans Carlijn , GeurtsvanKessel Corine , Hollander Jan den , Karim Faiz , Mollema Femke , Stalenhoef-Schukken Janneke , Dofferhof Anthonius , Ludwig Inge , Koster Adrianus , Hassing Robert-Jan , Bos Jeannet , Pottelberge Geert van , Vlasveld Imro , Ammerlaan Heidi , Segarceanu Elena van Leeuwen – , Miedema Jelle , Eerden Menno van der , Schrama Thijs , Papageorgiou Grigorois , Boekhorst Peter te , Swaneveld Francis , Mueller Yvonne , Scheurs Marco , Kampen Jeroen J. A. van , Rockx Barry , Okba Nisreen , Katsikis Peter , Koopmans Marion , Haagmans Bart , Rokx Casper , Rijnders Bart 
Published: November 2020

Abstract
Convalescent plasma could be an inexpensive and widely available treatment for COVID-19 patients but reports on effectiveness are inconclusive. We collected convalescent plasma from donors with high titers of neutralizing anti-SARS-CoV-2 antibodies effectively blocking SARS-CoV-2 infection in vitro. In a randomized clinical trial of 86 COVID-19 patients, no overall clinical benefit of 300 mL convalescent plasma was found in patients hospitalized for COVID-19 in the Netherlands. Using a comprehensive translational approach, we unraveled the virological and immunological responses following plasma treatment which helps to understand which COVID-19 patients may benefit from this therapy and should be the focus of future studies. Convalescent plasma treatment in this patient group did not improve survival, had no effect on the clinical course of disease, nor did plasma enhance viral clearance in the respiratory tract, influence anti-SARS-CoV-2 antibody development or serum proinflammatory cytokines levels. The vast majority of patients already had potent neutralizing anti-SARS-CoV-2 antibodies at hospital admission and at comparable titers as the carefully selected plasma donors. Together, these data indicate that the variable effectivity observed in trials on convalescent plasma for COVID-19 may be explained by the timing of treatment and varying levels of preexisting anti-SARS-CoV-2 immunity in patients. It also substantiates that convalescent plasma should be studied as early as possible in the disease course or at least preceding the start of an autologous humoral response. Trial registration: Clinicaltrials.gov: NCT04342182
Chemical Weathering of the Southern Tibetan Plateau: Study the Geochemical Weathering Indices in the Top Soils
Authors: Yang Xiaoyan , Hou Juzhi , San Feixue 
Published: November 2020

Abstract
Continental chemical weathering has been suggested to affect the concentration of atmospheric carbon dioxide that influences global climate change at different time scales. Various indices for chemical weathering have been adopted to investigate past change in chemical weathering intensity and climate change on oceanic and lacustrine sediment archives. The reliability of the chemical weathering indices has been questioned as most sediments likely originate from multiple types of bedrock that may experience various degrees of chemical weathering and can thus be reliably robust indicators of climate and paleoclimate. Here we present Sr-type (e.g. Rb/Sr Sr/Ba) and Na-type (e.g. CIA CIW PIA CPA) chemical weathering indices for top soils across the southern Tibetan Plateau to discuss the chemical weathering characteristic in the Tibetan Plateau and to examine their response to regional climate variation. The results of chemical indices and the A-CN-K ternary plot show that the southern Tibetan Plateau is under the carbonate control of the primary chemical weathering stage with the cold-dry climate. Correlation analyses show shat Sr-type indices co-vary with mean annual temperature and annual precipitation while Na-type indices show little consistence with regional climate. The climate condition is the dominant control of Sr-type indices of top soils in the study area and the bedrock may be the dominant control for the Na-type indices. We also compared the corresponding indices at a Holocene lacustrine sediment profile in the Qaidam Basin in the northeast Tibetan Plateau with regional climatic records which strongly supports our observation in the top soils. The results of the study suggest that for the relative cold and dry climate in Tibetan Plateau the Sr-type indices are more sensitive to climate condition than Na-type indices. This suggests that the Sr-type indices are likely more suitable than Na-type indices to reflect the change of climate on the Tibetan Plateau. Caution should be taken for using the Na-type indices for reconstructing the past change in climate for the study area.
Acinetobacter Corneal Ulcer, an Ocular Involvement by an Uncommon Organism; a Case Report and a Review of Literature
Authors: Sardarinia Mahsa , Rabani SeyedHossein , Aghai Gholamhoseyn , Ghiasian Leila 
Published: November 2020

Abstract
Acinetobacter group has been known as gram-negative, opportunistic, aerobic coccobacilli which exists on skin, mucus membranes and in the urinary tract with relatively low virulence. Some predisposing factors including underlying systemic diseases, using broad spectrum antibiotic, mechanical ventilation and etc. could pose the more sever involvement with Acinetobacter. In this study, we reported a patient with Acinetobacter corneal ulcer and a relatively comprehensive review literature about this rarely ocular involvement with this bacteria.
WITHDRAWN: Incidence and Predictors of Cardiovascular Disease Among Type 1 and Type 2 Diabetes Mellitus in Tertiary Health Care Setting of Ethiopia: 8-Year Retrospective Follow Up Study.
Authors: Debele Gebiso , Kefeni Bilisumamulifna , Kanfe Shuma , Ayele Tadesse , Wolde Haileab , Yenit Melaku , Ahmed Mohammedjud 
Published: November 2020

Abstract
Background: Cardiovascular disease (CVD) is a major cause of death and disability among people with diabetes in the world and it is being a major barrier to sustainable human development. Despite, CVDs have continued to devastate human survival, few studies in Ethiopia have focused on its prevalence which alone are insufficient to assess the risk of incident cardiovascular events. Therefore, we determined the incidence and predictors of cardiovascular disease among diabetic patients.Methods: A retrospective cohort study was conducted on 399 randomly selected diabetes patients. Data were entered using Epi-Data and analyzed using Stata version 14. Multivariable Weibull proportional hazards regression analysis was used to identify the predictors of CVDs (namely, coronary heart disease (CHD), stroke, and peripheral arterial disease (PAD)) at 5% level of significance. Results: After a median follow-up of 5.9 years, the overall incidence rate of CVD per 100 person–years was 2.71 (95% CI: 16.9–17.6). The Multivariable survival analysis showed a significant association of CKD; (Adjusted Hazard Ratio (AHR) (95%CI) 2.53 [1.36, 4.72]), Systolic blood pressure (SBP) >/= 140; (AHR (95%CI) (4.30 [2.12, 8.73]) and triglyceride >/= 200 mg/dl; (AHR (95%CI) (5.10 [2.02, 12.89]) with risk of incident CVD.Conclusion: CVD is being a public health problem among diabetic patients in Ethiopia. SBP >/= 140, chronic kidney disease and high triglyceride were independent predictors of new CVD among diabetic patients. These findings emphasize the need of attention for CVD patients with CKD and HTN comorbidities and longer follow up period using prospective study design to determine the long-term effects of predictors of CVD among diabetic patients.
Cardiovascular Disease Prevalence in Type 2 Diabetes – An Analysis of A Large German Statutory Health Insurance Database
Authors: Gabler Maximilian , Geier Silke , Mayerhoff Lukas , Rathmann Wolfgang 
Published: November 2020

Abstract
Background The aim of this study was to determine the prevalence of cardiovascular disease in persons with type 2 diabetes mellitus (T2D) in Germany. Methods A claims database with an age- and sex-stratified sample of nearly 4 million individuals insured within the German statutory health system was used. All patients aged ≥ 18 years with T2D documented between 1 January 2015 and 31 December 2015 and complete retrospective documentation of ≥ 5 years (continuous enrollment in the German statutory health system) before 2015 were selected based on a validated algorithm. Cardiovascular disease (CVD) events were identified based on ICD-10 and OPS codes according to a previous clinical study (EMPA-REG OUTCOME trial).Results The prevalence of T2D in Germany in 2015 was 9.9% (n=324,708). Using a narrow definition of CVD, the 6-year observation period prevalence of CVD was estimated as 46.7% [95% CI: 46.52%;46.86%]. Applying a wider CVD definition, the proportion of T2D patients who showed a history of CVD was 57.1% [95% CI: 56.9%;57.24%]. The prevalence of CVD in patients with T2D ranged from 36.3% to 57.1%, depending on the observation period and definition of CVD.Conclusions The results underline the need for a population-based registration of cardiovascular complications in T2D.
Non-esterified Very Long-chain Fatty Acids Are Accumulated in Colorectal Cancer Tissues
Authors: Hama Kotaro , Fujiwara Yuko , Hayama Tamuro , Ozawa Tsuyoshi , Nozawa Keijiro , Matsuda Keiji , Hashiguchi Yojiro , Yokoyama Kazuaki 
Published: November 2020

Abstract
Colorectal cancer (CRC) is a major cancer, and its precise diagnosis is especially important for the development of effective therapeutics. In a series of metabolome analyses, the levels of very long chain fatty acids (VLCFA) was shown to be elevated in CRC tissues, although the endogenous form of VLCFA has not been fully elucidated. In this study we analyzed the amount of non-esterified fatty acids, phospholipids and acyl-CoA species by liquid-chromatography–mass spectrometry and showed that VLCFA is accumulated as the non-esterified form in CRC tissues. We also showed that the expression level of elongation of very long-chain fatty acids 1 (ELOVL1) is increased, whereas fatty acid transport protein 4 (FATP4) is decreased in CRC tissues. Finally, we showed that the amount of non-esterified VLCFA species was significantly up-regulated in cultured cells overexpressing ELOVL1. Our results suggest that the upregulation of ELOVL1 and the down-regulation of FATP4 cooperatively lead to the accumulation of non-esterified VLCFA in CRC tissues.