bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding the role of social media in organizational change implementation
Authors: Naeem Muhammad 
Published: March 2020

Purpose
The purpose of this study is to identify the role of social media in implementing effective organizational change. The study illuminates how social media applications support the antecedents of organizational change in the workplace.

Design/methodology/approach
The study followed an interpretive approach based on qualitative design and grounded theory using 41 non-directive and semi-structured interviews with change leaders and change recipients. These respondents were chosen using purposive sampling and thematic analysis was then performed using NVivo 11-Plus software.

Findings
This research highlights how social media applications can be used to overcome the challenges of organizational change implementation. The findings of the study illuminate various emerging themes such as social media applications are beneficial for fostering knowledge sharing about change processes and enhancing effective communication during change formulation and implementation. It can increase the level of trust and participation in decision-making and decrease the level of resistance to change. Also, it can enhance the level of support for change acceptance in the workplace.

Practical implications
Social media application (SMAs) are helpful to foster informal, constructive and relevant discussion with respect to routines organizational tasks, employee concerns about new changes, information about job security and financial and non-financial benefits after change implementation. The effective and efficient use of SMAs helps organizations to foster knowledge amongst employees and they can address various critical issues i.e. employee uncertainties about change initiatives, social consensus on the solution of problems and interactive communication among social actors within a network.

Originality/value
The study represents an effort to explore seldom-researched aspects such as the role of social media in the context of change formulation and implementation at the workplace. Social media applications have become popular across the world and the speed of their usage is rising day by day, but their real contribution toward organizational change has not yet been fully understood.
Shelf stability of meat pickle developed from Kadaknath
Authors: Ranade Ashlesha , Singh Pradeep Kumar , Shrivastav Neeraj 
Published: March 2020

Purpose
This study aims to have a product with enhanced shelf stability from the Kadaknath bird. It is localized to its native tract in India and is unknown to a major part of the world. As in tropical countries, the meat products prepared have limited shelf-life and restricted market access, hence, the pickle was developed to enhance its access to areas other than a native tract of Kadaknath.

Design/methodology/approach
The product was developed to assess the effect of cooking and dehydration on sensory and microbial features while enhancing shelf stability. A comparison between cooking methods i.e. steam cooking (SC) and microwave cooking (MC) followed by dehydration to get steam cooked + dehydration (SCD) and microwave cooked + dehydration (MCD) were subjected for the study.

Findings
The study revealed that sensory evaluation, from 0 to 100 days, for all the sensory parameters indicated that SC and MC samples scored more values than SCD and MCD, however, with the storage the values increased initially on the 20th day followed by a gradual decrease. The total plate count (colony forming unit) on 0 day for SC and MC were 2.51 and 2.46, whereas for SCD and MCD the values were 1.94 and 1.98, respectively, indicating significantly (P = 0.01) lower values in dehydrated meat pickle preparations (SCD and MCD) in comparison to samples prepared without dehydration (SC and MC). Similarly, on the 60th day, the meat pickle treatments mentioned as SC and MC had the yeast and mold counts (colony forming unit) detected as 1.79 and 1.88, respectively, however, the organisms were not detectable in treatments SCD and MCD.

Practical implications
Developed product may be suitable for long distance marketing and making the local delicacy available to distant places.

Originality/value
The literature review indicated that though meat pickles have been prepared earlier most of the preparations involved chemical preservatives/antioxidants and trials with hurdles such as dehydration and cooking variations were scanty.
Analysis of balanced scorecard usage by private companies
Authors: Sharma Divesh , Sharma Umesh 
Published: March 2020

PurposeThe purpose of this paper is to examine the factors related to the use of the balanced scorecard (BSC) by private companies. Specifically, the authors examine how foreign ownership, focus on a global market beyond the local company’s geographic region and other sophisticated management accounting practices (MAPs) (activity-based costing, just-in-time and total quality management) are related to the use of the BSC.Design/methodology/approachThe paper takes a contingency theoretic perspective. The data in this study is based on responses to a survey questionnaire that was mailed to 300 non-listed private companies in Singapore. A total of 135 responses were received, but 23 were incomplete, and thus, rendered unusable. Therefore, the final sample for the study is 112 private companies yielding a 37.3 per cent response rate that is considered high for survey research.FindingsThe authors find significant associations between the use of BSC and foreign ownership, focus on a global market and other sophisticated MAPs. The authors find that foreign ownership and a global market focus are significantly and consistently related to the extent to which the BSC is used across seven different management control purposes. The authors also find some evidence of associations between other sophisticated MAPs and the extent to which the BSC is used for management control purposes.Practical implicationsPrivate companies can use the BSC to better manage risks and use it for purposes such as communicating strategy and objectives, setting targets, evaluating performance, rewarding employees and managers, motivating employees and managers, controlling performance and coordinating across activities, departments and/or functional areas. The study has limitations such as the model is limited and excludes the effects of other significant contingency factors such as organisational culture. It may be appropriate to interview organisational participants to learn more about how their national and organisational culture affects the decision to use the BSC.Originality/valueThe findings fill a critical void in the literature by providing new evidence on the determinants of the use of the BSC by private companies.
Reproducibility in Accounting Research: Views of the Research Community
Authors: HAIL LUZI , LANG MARK , LEUZ CHRISTIAN 
Published: March 2020

ABSTRACTWe have little knowledge about the prevalence of irreproducibility in the accounting literature. To narrow this gap, we conducted a survey among the participants of the 2019 JAR Conference on their perceptions of the frequency, causes, and consequences of irreproducible research published in accounting journals. A majority of respondents believe that irreproducibility is common in the literature, constitutes a major problem, and receives too little attention. Most have encountered irreproducibility in the work of others (although not in their own work) but chose not to pursue their failed reproduction attempts to publication. Respondents believe irreproducibility results chiefly from career or publication incentives as well as from selective reporting of results. They also believe that practices like sharing code and data combined with stronger incentives to replicate the work of others would enhance reproducibility. The views of accounting researchers are remarkably similar to those expressed in a survey by the scientific journal Nature. We conclude by discussing the implications of our findings and provide several potential paths forward for the accounting research community.
The Champagne Tap: Time to Pop the Cork?
Authors: Green Rebecca S. , Cruz Andrea T. , Freedman Stephen B. , Fleming Alesia H. , Balamuth Fran , Pruitt Christopher M. , Lyons Todd W. , Okada Pamela J. , Thompson Amy D. , Mistry Rakesh D. , Aronson Paul L. , Nigrovic Lise E. ,   for the Herpes Simplex Virus Study Group of the Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC)
Published: March 2020

AbstractBackgroundA “champagne tap” is a lumbar puncture with no cerebrospinal fluid (CSF) red blood cells (RBCs). Clinicians disagree whether the absence of CSF white blood cells (WBCs) is also required.AimsAs supervising providers frequently reward trainees after a champagne tap, we investigated how varying the definition impacted the frequency of trainee accolades.Materials & MethodsWe performed a secondary analysis of a retrospective cross‐sectional study of infants ≤60 days of age who had a CSF culture performed in the emergency department (ED) at one of 20 centers participating in a Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC) endorsed study. Our primary outcomes were a champagne tap defined by either a CSF RBC count of 0 cells/mm3 regardless of CSF WBC count or both CSF RBC and WBC counts of 0 cells/mm3.ResultsOf the 23,618 eligible encounters, 20,358 (86.2%) had both a CSF RBC and WBC count obtained. Overall, 3,147 (13.3%) had a CSF RBC count of 0 cells/mm3 and 377 (1.6%) had both CSF WBC and RBC counts of 0 cells/mm3 (relative rate 8.35, 95% confidence interval 7.51 to 9.27).ConclusionsIn infants, a lumbar puncture with a CSF RBC count of 0 cells/mm3 regardless of the CSF WBC count occurred eight‐times more frequently than one with both CSF WBC and RBC counts of 0 cells/mm3. A broader champagne tap definition would allow more frequent recognition of procedural success, with the potential to foster a supportive community during medical training, potentially protecting against burnout.
Enduring consequences of perinatal fentanyl exposure in mice
Authors: Alipio Jason B. , Brockett Adam T. , Fox Megan E. , Tennyson Stephen S. , deBettencourt Coreylyn A. , El‐Metwally Dina , Francis Nikolas A. , Kanold Patrick O. , Lobo Mary Kay , Roesch Matthew R. , Keller Asaf 
Published: March 2020

AbstractOpioid use by pregnant women is an understudied consequence associated with the opioid epidemic, resulting in a rise in the incidence of neonatal opioid withdrawal syndrome (NOWS) and lifelong neurobehavioral deficits that result from perinatal opioid exposure. There are few preclinical models that accurately recapitulate human perinatal drug exposure and few focus on fentanyl, a potent synthetic opioid that is a leading driver of the opioid epidemic. To investigate the consequences of perinatal opioid exposure, we administered fentanyl to mouse dams in their drinking water throughout gestation and until litters were weaned at postnatal day (PD) 21. Fentanyl‐exposed dams delivered smaller litters and had higher litter mortality rates compared with controls. Metrics of maternal care behavior were not affected by the treatment, nor were there differences in dams' weight or liquid consumption throughout gestation and 21 days postpartum. Twenty‐four hours after weaning and drug cessation, perinatal fentanyl‐exposed mice exhibited signs of spontaneous somatic withdrawal behavior and sex‐specific weight fluctuations that normalized in adulthood. At adolescence (PD 35), they displayed elevated anxiety‐like behaviors and decreased grooming, assayed in the elevated plus maze and sucrose splash tests. Finally, by adulthood (PD 55), they displayed impaired performance in a two‐tone auditory discrimination task. Collectively, our findings suggest that perinatal fentanyl‐exposed mice exhibit somatic withdrawal behavior and change into early adulthood reminiscent of humans born with NOWS.
Physicians’ and Attorneys’ Beliefs and Attitudes Related to the Brain Disease Model of Addiction
Authors: Avery Joseph J. , Avery Jonathan D. , Mouallem Joseph , Demner Adam R. , Cooper Joel 
Published: March 2020

Background and ObjectivesAddiction is increasingly considered a chronic, relapsing brain disease; however, many scholars still disagree with the brain disease model of addiction. We set out to provide evidence of attorneys’ and physicians’ beliefs regarding the model. First, we asked the following question: do attorneys and physicians affirm the full brain disease model, or its modified form, or do they believe that addiction is driven by deficits in self‐control or moral weakness? Second, we evaluated the extent to which such beliefs correspond to attitudes toward individuals with substance use disorders (SUDs).MethodsA questionnaire was sent to resident physicians (N = 301) and criminal defense attorneys (N = 483) practicing in the United States. It was comprised of (i) an attitudes measure, (ii) a measure regarding conceptions of addiction, and (iii) demographic questions.ResultsAttorneys were more likely to believe that individuals with SUDs had “practically no choice” about whether to seek and use, whereas physicians were more likely to believe that such individuals had “genuine choice.” For both groups of participants, the rejection of the full brain disease model of addiction was associated with more negative attitudes toward individuals with SUDs.Conclusion and Scientific SignificanceThese results represent an important advance, as past research has neglected attorneys’ attitudes and is inconclusive regarding the manner in which beliefs about the brain disease model of addiction are related to attitudes toward individuals with SUDs. Educating practitioners regarding this relationship would raise awareness regarding when and to what extent stigma is likely to be present, which may in turn provide a foundation from which to address stigma. (Am J Addict 2020;00:00–00)
Amniotic immune biomarkers as risk factors in women with different symptoms of threatened late miscarriage
Authors: Meng Lili , Wang Zhenhua , Reilly Marie , Zhang Shuning , Liu Xiuli , Lin Dijin , Liu Shengxin , Liu Yinglin , Zhang Jianping , Chen Hui 
Published: March 2020

AbstractProblemTo investigate risk factors that can help identify the possibility of pregnancy loss in threatened late miscarriage (TLM) patients with and without spontaneous uterine contractions.Method of studyAmniotic immune biomarkers (IL2β receptor, IL6, IL8, IL10, IL1β, and TNFα) were assayed, and “sludge” was assessed. Patients without intrauterine infections were treated and followed up until delivery, and pregnancy outcomes were recorded. The two groups were compared for the differences in biomarker levels and “sludge,” and the independent associations of biomarkers, “sludge,” and other maternal factors with late miscarriage were investigated.ResultsThe amniotic levels of IL2βR, IL8, and TNFα were higher in the group with contractions (P < .05). When considered alone, each of the six biomarkers was significantly associated with late miscarriage in the no‐contractions group and four of these (IL8, IL10, IL1β, and TNFα) in the contractions group (P < .05). Biomarker levels were correlated, and in multivariate Cox regression analysis, there was an independent effect only for IL8 in the no‐contractions group (HR = 18.16, 95% CI: 5.75‐57.43) and TNFα in the contractions group (HR = 4.11, 95% CI: 1.68‐10.08). For patients with contractions, IL10, IL8, and IL1β were different in those with and without “sludge,” but no such difference was seen in the no‐contractions group.ConclusionFor TLM patients without intrauterine infections, amniotic immune biomarkers differ between patients with different symptoms, not only for their levels but also for the impact of these biomarkers on the risk of late miscarriage. These findings suggest that the symptoms of TLM should be considered in the study of miscarriage risk.
Differential expression of SALL4 in CTCs derived from hydatidiform moles and gestational trophoblastic neoplasms
Authors: Xu Danfei , Feng Fengzhi , Pei Yuqing , Zhang Yujuan , Wu Yue , Guo Yi , Cui Wei 
Published: March 2020

AbstractProblemTo investigate EMT phenotype and SALL4 expression of circulating tumour cells (CTCs) in patients with gestational trophoblastic neoplasm (GTN).Method of studyCanPatrol CTC detection system in combination with SALL4 RNA in situ hybridization was used to investigate the profile of CTCs in different types of gestational trophoblastic disease (GTD). Circulating CTCs were phenotyped and annotated with SALL4 expression in 41 GTD patients, including 12 HM and 29 GTN, as well as 22 pregnant volunteers.ResultsA positive correlation between the number of CTC and serum β‐hCG concentration was found among the GTN patients. The number of E/M‐CTC was positively correlated with serum β‐hCG, while M‐CTC was positively correlated with prognostic score. Comparison among malignant GTD, benign GTD and healthy pregnant women revealed a significant difference in the number of total CTC, E/M‐CTC, and M‐CTC but not in E‐CTC. ROC analysis was conducted to evaluate the performance of CTC phenotypes in distinguishing GTD patients from healthy pregnant women yielding an AUC as 0.826. Youden's index was maximal at the cutoff value of 8.5/4 mL with sensitivity and specificity at 53.66% and 100%, respectively. SALL4 expression was evaluated in GTD patients with CTC count greater than cutoff value. SALL4 high expressing CTCs (>2 signal dots) were detected in 66.67% (10/15) of malignant GTD patients but not in benign patients (0/5).ConclusionDifferential expression of SALL4 was seen in CTCs derived from hydatidiform moles and GTN. CTC profiling may be developed as an adjunct marker to diagnose GTN.
Non‐immune hydrops fetalis was rare in Sweden during 1997‐2015, but cases were associated with complications and poor prognosis
Authors: Whybra Catharina , Källén Karin , Hansson Stefan R. , Gunnarsson Rolf 
Published: March 2020

AbstractAimThe study was designed to document the incidence of non‐immune hydrops fetalis (NIHF) at birth and characterise associated outcomes and obstetric complications.MethodsData on more than 1.9 million births were extracted from the Swedish Birth Register for 1997‐2015. Pregnancies not affected by NIHF served as controls. National registers on mortality and hospitalisations provided follow‐up information.ResultsThere were 309 cases of NIHF at birth corresponding to an incidence of 1.6 per 10 000, lower than in previous studies. NIHF was more frequent in mothers aged ≥35 years and with a history of stillbirth. Preterm delivery occurred in 77.7% in the NIHF group, including 31.7% before 32 weeks of gestation. Multiple births and Caesarean sections were reported more frequent in the NIHF group. NIHF was associated with poor outcome with 14.6% stillbirths and in 26.5% early neonatal death. Overall, 58.7% of live‐born children with NIHF were alive at 12 months compared with 99.7% of controls. The most common causes of death were cardiovascular diseases and thoracic abnormalities.ConclusionNIHF at birth is associated with obstetric complications and poor prognosis for the neonate related to underlying disease. The low incidence of NIHF observed in this study may reflect well‐developed antenatal care.
Dimorphic protein expression for Sox9 and Foxl2 genes in the testicles and ovaries of the urodele amphibian: Ambystoma mexicanum
Authors: Mendoza‐Cruz Eva , Moreno‐Mendoza Norma , Zambrano‐González Luis , Porras‐Gómez Tania Janeth , Villagrán‐SantaCruz Maricela 
Published: March 2020

AbstractAmbystoma mexicanum is an endemic salamander from Mexico. Due to its neotenic characteristics, it is considered an important model for regeneration and development studies. However, there is little research concerning the pattern of gene expression related to testicular and ovarian function. In this study, we analyse expression of the protein of the Sox9, Foxl2 and Vasa genes, and Δ5‐3βHSD enzyme activity in ovaries and testicles of A. mexicanum. Correlating morphology with the expression of Sox9 and Foxl2, we find that these genes manifest sexually dimorphic expression. Sox9 is expressed at higher levels in the testicle, whereas Foxl2 is specific to the ovary. Vasa was detected in spermatogonia in the anterior region of the testis, and in the ovary, it was located in previtellogenic oocytes. Δ5‐3βHSD was located in Leydig cells of the testicles and theca cells of the ovaries. In summary, the dimorphic expression of Sox9 and Foxl2, and that of Vasa in the germ line are similar to that described for other vertebrates, suggesting that the molecular mechanisms related to ovarian and testicular function in A. mexicanum follow a similar expression pattern that is not altered by neotenic characteristics.
A nonsense variant in NME5 causes human primary ciliary dyskinesia with radial spoke defects
Authors: Cho Eun Hye , Huh Hee Jae , Jeong Inyoung , Lee Nam Yong , Koh Won‐Jung , Park Hae‐Chul , Ki Chang‐Seok 
Published: March 2020

AbstractPrimary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder characterized by defects in the function or structure of motitle cilia. In most cases, causative variants result in axonemal dynein arm anomalies, however, PCD due to radial spoke (RS) and central pair (CP) of microtubules has been rarely reported. To identify the molecular basis of PCD characterized by RS/CP defects, we performed whole exome sequencing in PCD patients with RS/CP defects. We identified a homozygous nonsense variant (c.572G>A; p.Trp191*) in NME5, which encodes a protein component of the RS neck, in one PCD patient with situs solitus. Morpholino knockdown of nme5 in zebrafish embryos resulted in motile cilia defects with phenotypes compatible with ciliopathy. This is the first study to show NME5 as a PCD‐causative gene in humans. Our findings indicate that NME5 screening should be considered for PCD patients with RS/CP defects.