bluuebunny/crossref_metadata_2025_split huggingface dataset:
Propuesta de modelo de mentoría entre iguales en entornos universitarios
Authors: Alonso-García Miguel Aurelio 
Published: December 2020

In addition to the high number of mentoring publications, there are difficulties in determining the factors that contribute to the success of mentoring. In the present paper, a systematic review is carried out on the variables that have been used as predictors or antecedents, the process variables and the results in the peer mentoring studies in university environments.Most of the time, the programs are aimed at incoming students (mentees), who are accompanied by another's students (mentors) of higher levels, who facilitate their integration. The review allows proposing a systemic and multilevel model that relates the three types of variables and is intended to be useful to determine the characteristics that peer mentoring programs must have in a university environment from a social point of view; organizational, group and individual; the activities to be carried out in the mentoring meetings; and the different variables in which mentoring can have an impact such as abandonment rates, student integration, career satisfaction, health, etc.
Predicting Urinary Tract Infections With Interval Likelihood Ratios
Authors: Liang Tian , Schibeci Oraa Silvia , Rebollo Rodríguez Naomi , Bagade Tanvi , Chao Jennifer , Sinert Richard 
Published: December 2020

BACKGROUND:Protocols for diagnosing urinary tract infection (UTI) often use arbitrary cutoff values of urinalysis components to guide management. Interval likelihood ratios (ILRs) of urinalysis results may improve the test’s precision in predicting UTIs. We calculated the ILR of urinalysis components to estimate the posttest probabilities of UTIs in young children.METHODS:Review of 2144 visits to the pediatric emergency department of an urban academic hospital from December 2011 to December 2019. Inclusion criteria were age &lt;2 years and having a urinalysis and urine culture sent. ILR boundaries for hemoglobin, protein, and leukocyte esterase were “negative,” “trace,” “1+,” “2+” and “3+.” Nitrite was positive or negative. Red blood cells and white blood cells (WBCs) were 0 to 5, 5 to 10, 10 to 20, 20 to 50, 50 to 100, and 100 to 250. Bacteria counts ranged from negative to “loaded.” ILRs for each component were calculated and posttest probabilities for UTI were estimated.RESULTS:The UTI prevalence was 9.2%, with the most common pathogen being Escherichia coli (75.2%). The ILR for leukocyte esterase ranged from 0.20 (negative) to 37.68 (3+) and WBCs ranged from 0.24 (0–5 WBCs) to 47.50 (100–250 WBCs). The ILRs for nitrites were 0.76 (negative) and 25.35 (positive). The ILR for negative bacteria on urinalysis was 0.26 and 14.04 for many bacteria.CONCLUSIONS:The probability of UTI in young children significantly increases with 3+ leukocyte esterase, positive nitrite results, 20 to 50 or higher WBCs, and/or many or greater bacteria on urinalysis. The probability of UTI only marginally increases with trace or 1+ leukocyte esterase or 5 to 20 WBCs. Our findings can be used to more accurately predict the probability of true UTI in children.
Duflo-Moore Operator for The Square-Integrable Representation of 2-Dimensional Affine Lie Group
Authors: Kurniadi Edi , Gusriani Nurul , Subartini Betty 
Published: December 2020

In this paper, we study the quasi-regular and the irreducible unitary representation of affine Lie group of dimension two. First, we prove a sharpening of Fuhr’s work of Fourier transform of quasi-regular representation of . The second, in such the representation of affine Lie group is square-integrable then we compute its Duflo-Moore operator instead of using Fourier transform as in F hr’s work.
A educação e socialização de crianças com Transtorno de Espectro Autista: Uma aproximação ao papel do professor
Authors: Hernández González Osvaldo , Jamba Pedro Da Fonseca Amândio , António António 
Published: December 2020

No campo educacional cubano, entende-se que, para avançar no paradigma da pesquisa educacional, os professores devem estar atentos aos avanços que ocorrem nas ciências pedagógicas atuais, com o intuito de poder dar respostas eficientes e eficazes às demandas de alunos com necessidades educacionais especiais. O objetivo deste trabalho é refletir criticamente sobre alguns aspectos relevantes que interferem na preparação de professores para formar e estimular a socialização de alunos com Transtorno de Espectro Autista em condições de inclusão escolar. Este trabalho pode contribuir para enriquecer as discussões que acontecem nas ciências da educação contemporâneas e, portanto, pode servir de suporte e informação para quem toma decisões políticas em contextos educacionais inclusivos, especialmente para professores com responsabilidade social de educar e socializar alunos com transtornos de espectro autista.
Community-Based Mental Health Care in Britain
Authors: Burns Tom 
Published: December 2020

Community mental health care in the UK was established by two influential mental health acts (MHAs). The 1930 MHA legislated for voluntary admissions and outpatient clinics. The 1959 MHA required hospitals to provide local follow- up after discharge, required them to work closely with local social services and obliged social services to help with accommodation and support. An effect of this was to establish highly sectorized services for populations of about 50,000. These were served by multidisciplinary teams (generic CMHTs), which accepted all local referrals from family doctors. Sector CMHTs evolved a pragmatic approach with an emphasis on skill-sharing and outreach, depending heavily on community psychiatric nurses. The NHS is funded by central taxation, with no distortion of clinical practice by per-item service fees. It is highly centrally regulated, with a strong emphasis on evidence-based treatments.
Since 2000, generic sector teams have gradually been replaced or enhanced by Crisis Resolution Home Treatment teams, Assertive Outreach Teams and Early Intervention Teams. Assertive Outreach Teams were resorbed into CMHTs, based on outcome evidence. The last decade has seen a major expansion in outpatient psychotherapy (Improving Access to Psychological Treatments (IAPT) services) and in specialist teams for personality disorders and perinatal psychiatry. The traditional continuity of care across the inpatient-outpatient divide has recently been broken. During the last decade of austerity, day care services have been decimated, and (along with the reduction in availability of beds) compulsory admission rates have risen sharply. Mental health care is still disadvantaged, receiving 11% of the NHS spend while accounting for 23% of the burden of disease.
The Role of products of Microfinance for Reducing the Poverty of the Borrowers: Exploratory Factor Analysis
Authors: Kumari J.A Prasansha 
Published: December 2020

This paper intend to analyses the structural characteristics of microfinance and statistically categorized them in to five products of microfinance as independent variable and poverty reduction as dependent variable. Data were gathered from 494 borrowers of Samurdhi microfinance program in five districts in Sri Lanka using Likert scale questionnaire. The collected data analyzed by Exploratory Factor analysis using SPSS 21 version. The factor Metrix of the EFA results presented good pattern distribution among 38 items which indicated that six constructs loaded properly which is greater than acceptable threshold >0.5. Therefore, the results explored that the 38 items can be grouped properly into the six constructs based on their items.
Development of pharmacy competency framework for the changing demands of Thailand’s pharmaceutical and health services
Authors: Suwannaprom Puckwipa , Suttajit Siritree , Eakanunkul Suntara , Supapaan Teeraporn , Kessomboon Nusaraporn , Udomaksorn Khunjira , Sakulbumrungsil Rungpetch 
Published: December 2020

Background: In Thailand, pharmacists are responsible for all activities to ensure access to medicines throughout pharmaceutical supply chain. Competency framework (CF) is an important guidance for professional development and workforce planning.
Objective: This study aimed to explore needs for pharmacy services in pharmaceutical supply chain and competencies of pharmacists to serve those needs. It was the first step for developing evidence-based pharmacy CF within the context of Thailand in 2026.
Methods: A qualitative method using in-depth interviews to gain rich data from practitioners and leaders in all area of practices. 99 key informants from 56 workplaces in Thailand were interviewed during January and March 2016. Data was transcribed verbatim, and thematic analysis was used. Competencies were extracted, followed by several rounds of group discussion among team members to develop an initial framework. The competencies and CF were presented, and recommendations were gained from professional leaders for refining the findings.
Results: The key informants agreed that pharmacist’s works and responsibilities have gradually been drifted to support changes in healthcare and pharmaceutical systems. The upcoming pharmaceutical services call for higher standards of practice, larger number of personnel, and skillful pharmacists who have strong foundation in pharmaceutical knowledge as well as an ability to integrate knowledge into practices. Two sets of CFs were established. The general CF comprises five core domains: product focus, patient focus, healthcare system focus, community focus, and personal focus for self-improvement. These general competencies allow practitioners to perform basic professional tasks, including providing information, dispensing, and compounding. The service-specific competency is the integration of general competencies tailored into specific area of practice.
Conclusions: Regarding the professional goal to evolve pharmacists from generalists to specialists for providing higher quality of professional services, the pharmacists are required to demonstrate general competencies and service-specific competencies. The findings serve as the need-based evidence for developing a national CF for pharmacists in Thailand.
Kronik spontan ürtikerde omalizumab tedavisinin etkinliği: Retrospektif bir çalışma
Authors: YILDIRIM Fatmaelif 
Published: December 2020

Amaç: Bu çalışmada tedaviye dirençli kronik spontan ürtiker (KSÜ) nedeni ile omalizumab tedavisi kullanan hastaların klinik ve demografik özelliklerinin yanısıra omalizumab etkinliği ile yan etkilerinin geriye dönük olarak değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntemler: Kliniğimizde 2014-2017 yılları arasında H1-antihistaminiklere direnç nedeni ile 300 mg/ay subkutan omalizumab başlanan KSÜ hastalarının kayıtlı bilgisayar verileri taranarak retrospektif olarak incelendi. Hiç ürtikeryal plağı ve kaşıntısı olmayanlar tam yanıtlı, tedavi başlangıcına göre hayat kalitesi artan ve semptomlarında belirgin iyileşme olanlar kısmi yanıtlı, semptomlarında hiç iyileşme olmayanlar yanıtsız olarak kabul edildi.
Bulgular: Tedaviye dirençli KSÜ nedeniyle omalizumab verilen 71 (41 K, 30 E) hasta çalışmaya dahil edildi. Bu hastaların ortalama hastalık süresi 54.6±52.9 (min-maks:8-360) ay olup, yaş ortalaması 43.6±16.4 (min-maks: 14-83) yıl idi. Omalizumab tedavisi 3. ayı sonunda hastaların yapılan değerlendirilmesinde, 14 (19.7%) hastada tam yanıt, 36 (50.7%) hastada kısmı yanıt görülürken, 21 (%29,6) hastada yanıt alınamadı. Başlangıç total IgE ve CRP düzeyleri, hastalık süresi, hasta yaşı, cinsiyeti, astım öyküsü ve immünsupresif kullanım öyküsü açısından 3. ay sonu omalizumab tedavisi yanıt grupları arasında herhangi bir istatistiksel farklılık tespit edilmedi (p>0.05). Hastalarda ciddi bir yan etki saptanmadı.
Sonuç: Bu çalışmada, KSÜ nedeniyle takip edilip omalizumab kullanılan hastalarda, omalizumab tedavisinin etkin ve güvenilir olduğunu tespit ettik.
CHAMADA PÚBLICA nº. 02/2017 - O Império e as Prová­ncias: configurações do estado nacional brasileiro no século XIX
Authors: Cavalcante Anissa Ayala 
Published: December 2020

A Revista Outros Tempos, do Curso de História da Universidade Estadual do Maranhão (UEMA), torna pública a chamada de nº 02/2017, para seleção de Artigos, Resenhas e Estudo de Caso, que comporão o volume 15 número 26, do mês de julho/dezembro de 2018, para o dossiê temático ”O Império e as Prová­ncias: configurações do estado nacional brasileiro no século XIX”, sob organização de Wilma Peres Costa, professora da Universidade Federal de São Paulo (UNIFESP/Brasil) e Marcelo Cheche Galves, professor da Universidade Estadual do Maranhão (UEMA/Brasil).
CHAMADA PÚBLICA n. 04/2019 - Dossiê: ”História Antiga pra quê?” Questões antigas para problemas contemporá¢neos”
Authors: Cavalcante Anissa Ayala 
Published: December 2020

A Revista Outros Tempos, do Curso de História da Universidade Estadual do Maranhão (UEMA), torna pública a chamada de nº 04, para seleção de Artigos, Resenhas e Estudo de Caso, que irão compor o volume 16, número 28, jul./dez., 2019, para o dossiê temático: ”História Antiga pra quê?” Questões antigas para problemas contemporá¢neos”, sob organização de: Ana Livia Bomfim Vieira, professora da Universidade Estadual do Maranhão (UEMA/Brasil)
[ARTIGO TRADUZIDO] IDEOLOGY AND TRADITION OF DRUG USERS IN THE COLONIAL AMAZONIA
Authors: AVELAR LUCAS ENDRIGO BRUNOZI 
Published: December 2020

Abstract: In this text, we seek to indicate how the bearers of a religious ideology of medieval origin described the drunkenness of the indigenous peoples in the 18th century Amazon. We privileged the analysis of the accounts of the work ”Tesouro Descoberto no Máximo Rio Amazonas” by the Portuguese Jesuit, João Daniel. Highlighting the contradictions and approximations established between, on the one hand, a colonization based on the production and commerce of drugs and Catholic food tradition based on wine and bread, and on the other hand, an ideology of abuse elaborated to account for the indigenous tradition of drinks ingestion and substances extracted from the forest. Keywords: Colonial Amazon. Drunkenness. Drugs. Missionaries.
Apport Des NÃ©gro-Africains Au DÃ©veloppement De La GÃ©omancie Et De La MathÃ©matique
Authors: Mayer Raoul Ã‰tonguÃ© 
Published: December 2020

Les impressions et les interprÃ©tations d'artefacts archÃ©ologiques dÃ©pendent en grande partie de l'expÃ©rience personnelle. Elles ne font appel Ã aucune autoritÃ© dogmatique, car elles adhÃ¨rent Ã©troitement Ã la vÃ©ritÃ© recherchÃ©e par les scientifiques qui veulent expliquer les palÃ©o environnements en fonction de lâ€™expÃ©rience des donnÃ©es recueillies. Dans le cas prÃ©sent, l'analyse des donnÃ©es et les conclusions ont permis de confectionner ce que l'on pourrait, par exemple, appeler le discours des os d'Ishango. L'objectif de ce travail est d'amÃ©liorer la comprÃ©hension du petit os d'Ishango en confrontant le dÃ©chiffrement de ses caractÃ©ristiques et une feuille de ponctuation d'un thÃ¨me gÃ©omantique. La mÃ©thode gÃ©omantique qui consiste Ã faire une sÃ©rie de petites lignes verticales a alors Ã©tÃ© appliquÃ©e Ã la lecture et Ã l'analyse du symbolisme du petit os dâ€™Ishango. La lecture visuelle de la morphologie structurale du petit os d'Ishango a Ã©tÃ© rÃ©alisÃ©e en utilisant le corpus Ã©sotÃ©rique des connaissances de la religion universelle transmises dans le secret initiatique depuis la nuit des temps. Les analogies confirment un lien fort entre les connaissances occultes, la gÃ©omancie et les mathÃ©matiques dans la conception des os d'Ishango qui a eu lieu aux confins des Grands lacs africains il y a au moins 25 ka.
Impressions and interpretations of archeological artefacts are drawn largely from peopleâ€™s personal experience not appealing to any dogmatic authority, but because they closely adhere to the truth, adamantly hunted by scientists who want to explain paleo environments based on gathered evidence. Analysis of evidence, and findings worked out a set of assumptions what might for instance, be called the discourse of the Ishango bones. The objective of this paper is to improve the understanding of smaller Ishango bone by confronting the deciphering of its strokes and a punctuation sheet of a geomantic theme. Geomantic method of making a series of strokes is applied to the analysis of the symbolism of smaller Ishango bone. Consequently, a visual reading of the structural morphology of smaller Ishango bone was used based on esoteric corpus of knowledge related to the universal religion of the ancient and prehistoric world. Analogies confirm a strong tie between occult knowledge, geomancy and mathematics in the designing of the Ishango bones that took place on the edge of African Great Lakes at least 25 ka ago.
Apitherapy and Health
Authors: ÖZDEMİR Gökçe , ERSÖZ Elmas , DİLEK Nazik 
Published: December 2020

Apitherapy is a word derived from the Latin word apis, meaning bee. Apitherapy application dates back hundreds of years. There are documents showing that physicians in Ancient Egypt and China used some bee products 4 thousand years ago. Apitherapy is used as an effective method for maintaining health and treating diseases. The main products used in this method are honey, apilarnil, propolis, royal jelly and perga. These products used in apitherapy are generally known to have very important effects such as antibacterial, antioxidant, anti-inflammatory, vasodilating and antitumor effects. In addition to its positive effects, studies have shown that the use of some apitherapy products may cause an allergic reaction. As a result, the use of these nutrients obtained from reliable sources has beneficial effects on health.
ARIA 2019: Um Percurso Assistencial Integrado para a Rinite Alérgica em Portugal
Authors: Fonseca João , Taveira-Gomes Tiago , Pereira Ana Margarida , Branco-Ferreira Manuel , Carreiro-Martins Pedro , Alves-Correia Magna , Correia de Sousa Jaime , Costa Elísio , Lourenço Olga , Morais-Almeida Mário , Morête Ana , Regateiro Frederico , Todo Bom Ana , Bachert Claus , Pfaar Oliver , Wallace Dana , Bedbrook Anna , Czarlewski Wienczyslawa , Bousquet Jean 
Published: December 2020

A iniciativa Allergic Rhinitis and Its Impact on Asthma (ARIA) teve início há mais de 20 anos e tem elaborado e disseminado orientações baseadas em evidência, e desenvolvido projetos na área da rinite alérgica. Esta iniciativa está atualmente focada em proporcionar orientações centradas no doente que contribuam para um percurso integrado entre os vários níveis de cuidados e que tirem partido de soluções digitais, tendo sido recomendada a introdução na prática clínica de percursos assistenciais integrados. Neste artigo descrevemos a adaptação para Portugal do documento ARIA Integrated Care Pathways. Após breve revisão sobre a epidemiologia e o impacto da rinite alérgica em Portugal e das atividades realizadas em Portugal no âmbito da iniciativa ARIA, é descrito o conjunto alargado de conhecimento utilizado para o desenvolvimento das recomendações para o tratamento farmacológico da rinite alérgica, recomendações essas baseadas na metodologia GRADE, evidência do mundo real adquirida por tecnologia móvel (mHealth) e resultante de estudos de câmara de exposição alergénica. Em seguida, são resumidos os percursos assistenciais integrados para imunoterapia com alergénios produzidas em 2019. Considera-se a imunoterapia com alergénios um exemplo de medicina de precisão e em que a utilização de tecnologias mHealth permitirá melhorar a estratificação para seleção dos doentes e monitorização da resposta. Estas recomendações foram consideradas como ‘boas práticas’ dos cuidados integrados centrados no doente apoiados por sistemas digitais da DG Santé (Direção Geral de Saúde e de Segurança Alimentar da União Europeia) e representam a estratégia de gestão da mudança da fase 4 do ARIA.
AKTIVITAS ANTI DIABETES MELLITUS TANAMAN DURIAN (Durio zibethinus Murr.) TERHADAP KADAR GLUKOSA DARAH PUASA MENCIT YANG DIINDUKSI ALOKSAN
Authors: Amir Muh. Nur , Sulitiani Yuyun , Indriani Indriani , Pratiwi Inda , Wahyudin Elly , Manggau Marianti A , Sumarheni Sumarheni , Ismail Ismail 
Published: December 2020

Durian (Durio zibethinus Murr.) telah lama digunakan sebagai salah satu pengobatan tradisional untuk mengobati berbagai macam penyakit, termasuk untuk penderita diabetes mellitus. Penelitian ini bertujuan untuk menentukan aktivitas ekstrak etanol durian dalam menurunkan kadar glukosa darah pada mencit yang diinduksi aloksan dosis 125 mg / kgBB dan diberi beban glukosa 20%. Sebanyak 36 ekor mencit dibagi menjadi 6 kelompok perlakuan. Kelompok I sebagai kontrol sehat, kelompok II diinduksi dengan aloksan dan diberikan NaCMC 1% (kontrol negatif), kelompok III diinduksi dengan aloksan dan diberikan Acarbose® (kontrol positif), kelompok IV diinduksi dengan aloksan dan diberikan ekstrak etanol akar durian (EDR), ekstrak klika (ESB) dan ekstrak daun (EDL) dosis 125 mg / kgBB, kelompok V diinduksi dengan aloksan dan diberikan ekstrak etanol akar durian (EDR), ekstrak klika (ESB) dan ekstrak daun (EDL) dosis 250 mg / kgBB, kelompok VI diinduksi dengan aloksan dan diberikan ekstrak etanol akar durian (EDR), ekstrak klika (ESB) dan ekstrak daun (EDL) dosis 500 mg / kgBB. Pengukuran kadar glukosa darah dilakukan sebelum induksi alloxan (t-0), 3x24 jam setelah induksi (t-3), dan setiap 30 menit setelah pemberian perlakuan ekstrak dan larutan glukosa hingga menit ke-180 (t30, t60, t90, t120, t150 dan t180), yang dilakukan pengukuran menggunakan alat glukometer (Nesco®). Persen penurunan kadar glukosa darah yang paling tinggi ditunjukkan setelah menit ke-180 pada kelompok EDR dengan dosis 125 mg / kgBB, ESB dosis 250 mg / kgBB dan EDL dosis 500 mg / kgBB yaitu sebesar 50,60%, 105,62%, dan 62,97%.
Identifikasi Mekanisme Fungsional Senyawa Bioaktif Peptida dari Organisme Laut sebagai Inhibitor Alami Angiotensin-I Converting Enzyme (ACE) secara In silico
Authors: Fakih Taufik Muhammad , Dewi Mentari Luthfika 
Published: December 2020

Inhibitor alami Angiotensin-I Converting Enzyme (ACE) berbasis peptida bioaktif saat ini menjadi fokus penelitian karena sifatnya yang unik dan memilki berbagai peran biologis penting diantaranya adalah sebagai kandidat pengobatan hipertensi. Terdapat beberapa peptida bioaktif yang dihasilkan oleh organisme laut dan telah terbukti mampu menghambat enzim ACE, antara lain peptida bioaktif yang berasal dari udang (SV, IF, dan WP) serta peptida bioaktif yang berasal dari ikan hiu (CF, EY, MF, dan FE). Pada penelitian ini dilakukan identifikasi, evaluasi, dan eksplorasi terhadap interaksi yang terjadi antara molekul peptida bioaktif dengan makromolekul ACE secara in silico menggunakan motode penambatan molekuler berbasis protein-peptida. Sekuensing peptida bioaktif dimodelkan menjadi konformasi 3D terlebih dahulu menggunakan software PEP-FOLD. Konformasi terbaik dipilih untuk kemudian dilakukan studi interaksi molekuler terhadap makromolekul ACE menggunakan software PatchDock. Interaksi molekuler yang terjadi diamati lebih lanjut menggunakan software BIOVIA Discovery Studio 2020. Berdasarkan hasil dari penambatan molekuler berbasis protein-peptida, peptida bioaktif CF dan IF yang berasal dari udang dan peptida bioaktif MF yang berasal dari ikan hiu memiliki afinitas yang baik, yaitu dengan ACE score masing-masing adalah −380,62 kJ/mol, −436,43 kJ/mol, dan −349,91 kJ/mol. Dengan demikian, peptida bioaktif laut tersebut diprediksi dapat dipilih sebagai kandidat inhibitor alami enzim ACE berbasis peptida sebagai alternatif antihipertensi.