bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of predictive scores for late and very late recurrence after cryoballoon-based ablation of atrial fibrillation
Authors: Sano Makoto , Heeger Christian-Hendrik , Sciacca Vanessa , Große Niels , Keelani Ahmad , Fahimi Behzad Hassan Hosseiny , Phan Huong Lan , Reincke Samuel , Brüggemann Ben , Fink Thomas , Liosis Spyridon , Vogler Julia , Eitel Charlotte , Tilz Roland Richard 
Published: July 2020

Abstract
Purpose
Studies on predictive scores for very late recurrence (VLR) (recurrence later than 12 months) after second-generation cryoballoon-based pulmonary vein isolation (CB2-PVI) are sparse. We aimed to evaluate the frequency of late recurrence (LR) (later than 3 months) and VLR, and to validate predictive scores for LR and VLR after initial CB2-PVI.

Methods
A total of 288 patients undergoing initial CB2-PVI (66 ± 11 years, 46% paroxysmal) were retrospectively enrolled in the LR cohort. In the VLR cohort, 83 patients with recurrence within 3–12 months or with < 12-month follow-up were excluded. The predictive scores of arrhythmia recurrence were assessed, including the APPLE, DR-FLASH, PLAAF, BASE-AF2, ATLAS, SCALE-CryoAF, and MB-LATER scores.

Results
During a mean follow-up of 15.3 ± 7.1 months, 188 of 288 (65.2%) patients remained in sinus rhythm without any recurrences. Thirty-two of 205 (15.6%) patients experienced VLR after a mean of 16.6 ± 5.6 months. Comparing the predictive values of these specific scores, the MB-LATER score showed a reliable trend toward greater risk of both LR and VLR (area under the curve in LR; 0.632, 0.637, 0.632, 0.637, 0.604, 0.725, and 0.691 (p = ns), VLR; 0.612, 0.636, 0.644, 0.586, 0.541, 0.633, and 0.680 (p = 0.038, vs. BASE-AF2, respectively)). Kaplan-Meier analysis estimated patients with higher MB-LATER scores which had favorable outcomes (24-month freedom from LR; 26.0% vs. 56.7%, p < 0.0001, VLR; 53.4% vs. 82.1%, p = 0.013).

Conclusion
The MB-LATER score provided more reliable predictive value for both LR and VLR. Patients with higher MB-LATER scores may benefit from more intensive long-term follow-up.
RETRACTED ARTICLE: Modelling the interaction between tourism, energy consumption, pollutant emissions and urbanization: renewed evidence from panel VAR
Authors: Adedoyin Festus Fatai , Bekun Festus Victor 
Published: July 2020

AbstractIn less than two decades, the global tourism industry has overtaken the construction industry as one of the biggest polluters, accounting for up to 8% of global greenhouse gas emissions as reported by the United National World Trade Organization (UNWTO 2018). This position resonates the consensus of the United Nations Framework Convention on Climate Change (UNFCCC). Consequently, research into the causal link between emissions and the tourism industry has increased significantly focusing extensively on top earners from the industry. However, few studies have thoroughly assessed this relationship for small island economies that are highly dependent on tourism. Hence, this study assessed the causal relationship between CO2 emissions, real GDP per capita (RGDP) and the tourism industry. The analysis is conducted for seven tourism-dependent countries for the period 1995 to 2014 using panel VAR approach, with support from fully modified ordinary least square and pooled mean group–autoregressive distributed lag models. Unit root tests confirm that all variables are stationary at first difference. Our VAR Granger causality/block exogeneity Wald test results show a unidirectional causality flowing from tourism to CO2 emission, RGDP and energy consumption, but a bi-directional causality exists between tourism and urbanization. This implies that in countries that depend on tourism, the behaviour of CO2 emission, RGDP and energy consumption can be predicted by the volume of tourist arrivals, but not the other way around. The impulse response analysis also shows that the responses of tourism to shocks in CO2 appear negative within the 1st year, positive within the 2nd and 3rd years but revert to equilibrium in the fourth year. Finally, the reaction of tourism to shocks in energy consumption is similar to its reaction to shocks in RGDP. Tourism responds positively to shocks in urbanization throughout the periods. These outcomes were resonated by the Dumitrescu and Hurlin causality analysis where the growth-induced tourism hypothesis is validated as well as feedback causality observed between tourism and pollutant emission and urbanization and pollutant emission in the blocks over the sampled period. Consequently, this study draws pertinent energy and tourism policy implications for sustainable tourism on the panel over their growth trajectory without compromise for green environment.
Impact of Unannounced Standardized Patient Audit and Feedback on Care, Documentation, and Costs: an Experiment and Claims Analysis
Authors: Schwartz Alan , Peskin Steven , Spiro Alan , Weiner Saul J. 
Published: July 2020

Abstract
Background
Meaningful variations in physician performance are not always discernible from the medical record.

Objective
We used unannounced standardized patients to measure and provide feedback on care quality and fidelity of documentation, and examined downstream effects on reimbursement claims.

Design
Static group pre-post comparison study conducted between 2017 and 2019.

Setting
Fourteen New Jersey primary care practice groups (22 practices) enrolled in Horizon BCBS’s value-based program received the intervention. For claims analyses, we identified 14 additional comparison practice groups matched on county, practice size, and claims activity.

Participants
Fifty-nine of 64 providers volunteered to participate.

Intervention
Unannounced standardized patients (USPs) made 217 visits portraying patients with 1–2 focal conditions (diabetes, depression, back pain, smoking, or preventive cancer screening). After two baseline visits to a provider, we delivered feedback and conducted two follow-up visits.

Measurements
USP-completed checklists of guideline-based provider care behaviors, visit audio recordings, and provider notes were used to measure behaviors performed and documentation errors pre- and post-feedback. We also compared changes in 3-month office-based claims by actual patients between the intervention and comparison practice groups before and after feedback.

Results
Expected clinical behaviors increased from 46% to 56% (OR = 1.53, 95% CI 1.29–1.83, p < 0.0001), with significant improvements in smoking cessation, back pain, and depression screening. Providers were less likely to document unperformed tasks after (16%) than before feedback (18%; OR = 0.74, 95% CI 0.62 to 0.90, p = 0.002). Actual claim costs increased significantly less in the study than comparison group for diabetes and depression but significantly more for smoking cessation, cancer screening, and low back pain.

Limitations
Self-selection of participating practices and lack of access to prescription claims.

Conclusion
Direct observation of care identifies hidden deficits in practice and documentation, and with feedback can improve both, with concomitant effects on costs.
‘I Am that I Am’ (Ex. 3.14): from Augustine to Abhishiktānanda—Holy Ground Between Neoplatonism and Advaita Vedānta
Authors: Soars Daniel 
Published: July 2020

AbstractWe shall revisit a debate which has been going on at least since pioneering British Indologists like William Jones first encountered the ‘Brahmanic theology’ we now know as Vedānta, namely, the nature of the relationship—if any—between certain forms of ‘western’ and ‘Indian’ idealisms, and how these metaphysical systems have influenced Christian theology. Specifically, we look at the question of possible thematic and conceptual convergences between Neoplatonism and Advaita Vedānta, and argue that significant parallels can be found in their common conception of the Absolute as Being. Rather than attempt a comprehensive overview of the two systems, we take the divine ‘I AM’ revealed to Moses in Exodus 3.14 as thelocus classicusof Christian philosophical interpretations of God as Being itself, and explore how four seminal figures read this passage in light of Neoplatonic and Vedāntic influences. We shall see that similarities and divergences in the readings of Augustine, Thomas Aquinas, Meister Eckhart and Henri Le Saux can be understood in terms of how they negotiate the relation between the One and the many, or between ‘being’ and ‘knowing’. The more these figures allow themselves to be influenced by Neoplatonism and Advaita Vedānta, the more we see any clear ontological distinction between creature and Creator start to break down. This verse, therefore, proves to be an unusually fruitful test case for exploring the relation between the underlying Neoplatonic and Vedāntic metaphysics which structure varying Christian interpretations of it.
Integrating Value Considerations in the Decision Making for the Design of Biorefineries
Authors: Palmeros Parada Mar , Asveld Lotte , Osseweijer Patricia , Posada John Alexander 
Published: July 2020

AbstractBiobased production has been promoted as a sustainable alternative to fossil resources. However, controversies over its impact on sustainability highlight societal concerns, value tensions and uncertainties that have not been taken into account during its development. In this work, the consideration of stakeholders’ values in a biorefinery design project is investigated. Value sensitive design (VSD) is a promising approach to the design of technologies with consideration of stakeholders’ values, however, it is not directly applicable for complex systems like biorefineries. Therefore, some elements of VSD, such as the identification of relevant values and their connection to a technology’s features, are brought into biorefinery design practice. Midstream modulation (MM), an approach to promoting the consideration of societal aspects during research and development activities, is applied to promote reflection and value considerations during the design decision making. As result, it is shown that MM interventions during the design process led to new design alternatives in support of stakeholders' values, and allowed to recognize and respond to emerging value tensions within the scope of the project. In this way, the present work shows a novel approach for the technical investigation of VSD, especially for biorefineries. Also, based on this work it is argued that not only reflection, but also flexibility and openness are important for the application of VSD in the context of biorefinery design.
Current Consensus of Dental Implants in the Elderly—What Are the Limitations?
Authors: Sato Yuji , Kitagawa Noboru , Isobe Akio 
Published: July 2020

Abstract

Purpose of Review
This review examines the restricting factors based on the current situation of implant treatments in elderly people and describes how they should be handled. In addition, it is suggested to establish an environment in which the oral cavity of the patient can be managed at the end of treatment with an implant card detailing the implant treatments provided, while anticipating the patient’s aging.

Recent Findings
Implant treatments now account for a large proportion of dental prosthetic treatment options. Meanwhile, aging is accelerating globally, with Japan at the top of the list. This has resulted in an increase in the number of implant patients who are elderly and require care and who have systemic problems. Furthermore, with the growing number of people in need of nursing care, there is a growing need to care elderly people who have received implant treatments in the past, and there are various issues in handling such cases. It is also important to properly evaluate the systemic conditions, conduct less-invasive surgeries using appropriate types of implant system based on estimated life expectancy, and provide treatments using prosthetic devices that can be easily managed and modified.

Summary
The systemic conditions and aging of the oral cavity need to be taken into consideration regarding the risks of implant surgery. As to the worsening of maintenance condition, changing to a removable superstructure as well as awareness-raising activities should be examined. In addition, we suggest that policy measures be taken to address some issues regarding training, manufacturers, and medical insurance. We hope that implant treatments will continue to contribute to patients as we head toward becoming a super-aging society.
Extensively Drug-Resistant Tuberculosis in the Time of COVID-19—How has the Landscape Changed for Pakistan?
Authors: Islam Mahnoor 
Published: July 2020

ABSTRACTThe incidence of extensively drug-resistant tuberculosis (XDR-TB) has been rising consistently in Pakistan, and the country is likely to experience another surge of cases in the midst of the COVID-19 crisis. It is imperative to consider how the rising proportion of XDR-TB is best tackled during the pandemic; this includes finding a solution to the problem of non-adherence at the level of community-based healthcare, the utility and practicality of simultaneous testing for COVID-19 and TB, and reconciliation of the World Health Organization’s recommendation of home-based treatment with the need for frequent monitoring of anti-tubercular therapy in XDR-TB. Operational research is needed expeditiously to bypass these limitations.
Abdominal angiostrongyliasis: pathologic findings in Swiss mice infected with different doses of Angiostrongylus costaricensis
Authors: Hermes C.C. , Benvegnú E. , Costa M.M. , Rodriguez R. , Vieira M.I.B. 
Published: July 2020

Abstract
Abdominal angiostrongyliasis is caused by Angiostrongylus costaricensis, the definitive and intermediate hosts of which are wild rodents and terrestrial molluscs, respectively. Humans are accidental hosts and can be infected by ingesting the third-stage (infective) larvae (L3). It remains unclear whether the number of L3 inoculated is related to lesion severity. Our aim was to analyse histopathological alterations in Swiss mice infected with different doses of A. costaricensis. Thirty-two mice were randomly divided into four groups (n = 8/group): uninfected, control mice; mice infected with a low dose (five L3); mice infected with an intermediate dose (15 L3); and mice infected with a high dose (30 L3). The frequency of intestinal thrombi, splenitis, eggs/larvae, hepatic infarction and acute pancreatitis differed among the groups, the last being considered a significant finding. We conclude that different infective doses alter the histopathological aspects of the infection in Swiss mice, those aspects being more pronounced at medium and high doses, with no effect on the development of the disease. This experimental model shows that the parasite life cycle can be maintained in Swiss mice through the inoculation of a low dose (five L3).
The Ford Administration, the National Security Agency, and the “Year of Intelligence”: Constructing a New Legal Framework for Intelligence
Authors: ROADY PETER 
Published: July 2020

Abstract:In the mid-1970s, Congress and the judiciary moved to regulate the National Security Agency (NSA) at a moment when such regulation might have restricted the growth of electronic surveillance. The Ford administration played a crucial role in preventing that from happening. It did so by controlling the flow of intelligence information to Congress and by establishing a flexible new legal framework for intelligence based on broad executive orders, narrow legislation, and legal opinions written by executive branch lawyers. This framework fostered a perception of legality that headed off calls for comprehensive legislation governing intelligence. The Ford administration’s actions protected NSA from meaningful regulation, preserved the growth of electronic surveillance, and sustained executive branch preeminence in national security affairs. The episode proved formative for the Ford administration officials involved—including Dick Cheney, Donald Rumsfeld, and Antonin Scalia—and solidified the central role of executive branch lawyers in national security policymaking.
Epidemiological and clinical characteristics of a familial cluster of COVID-19
Authors: Sun Yong , Tian Lin , Du Xiaomei , Wang Hua , Li Yueshan , Wu Rangbing 
Published: July 2020

Abstract
We report a family cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involving five patients in a family cluster in Dazhou, China, including the epidemiological, clinical, laboratory and radiological findings. Three-generation transmission was observed. Through epidemiological investigation, we observed asymptomatic transmission to a cohabiting family member, as well as person-to-person transmission of SARS-CoV-2 outside Wuhan city. The asymptomatic transmission demonstrated here provides evidence that there could be a greater risk of Coronavirus Disease 2019 (COVID-19) spread. This cluster also demonstrated that COVID-19 is transmissible during the incubation period of an asymptomatic person. Early isolation and treatment, stressing prevention of cluster outbreaks, could help prevent further spread of the epidemic.
Robust long-term interest rate risk hedging in incomplete bond markets
Authors: Shen Sally , Pelsser Antoon , Schotman Peter 
Published: July 2020

AbstractPricing ultra-long-dated pension liabilities under the market-consistent valuation is challenged by the scarcity of the long-term market instruments that match or exceed the terms of pension liabilities. We develop a robust self-financing hedging strategy which adopts a min–max expected shortfall hedging criterion to replicate the long-dated liabilities for agents who fear parameter misspecification. We introduce a backward robust least squares Monte Carlo method to solve this dynamic robust optimization problem. We find that both naive and robust optimal portfolios depend on the hedging horizon and the current funding ratio. The robust policy suggests taking more risk when the current funding ratio is low. The yield curve constructed by the robust dynamic hedging portfolio is always lower than the naive one but is higher than the model-based yield curve in a low-rate environment.
Projections of Extreme Ocean Waves in the Arctic and Potential Implications for Coastal Inundation and Erosion
Authors: Casas‐Prat Mercè , Wang Xiaolan L. 
Published: July 2020

AbstractThe Arctic Ocean wave climate is undergoing a dramatic change due to the sea ice retreat. This study presents simulations of the Arctic regional wave climate corresponding to the surface winds and sea ice concentrations as simulated by five CMIP5 (Coupled Model Intercomparison Project Phase 5) climate models for the historical (1975–2005) and RCP8.5 scenario future (2081–2100) periods. The annual maximum significant wave height is projected to increase up to 6 m offshore and up to two to three times greater than the corresponding 1979–2005 value along some coastlines, as waves become more exposed to the fall storms there. The connection between the Atlantic Ocean and the Arctic wave climates is projected to strengthen due to increase of swell influence. Changes in the wave direction also seem to indicate a weakening of the Beaufort High illustrated by a counterclockwise rotation of the mean wave direction for extreme conditions in the Western Arctic. The projected changes in wave conditions lead to a general increase of the wave‐driven erosion and inundation potential along the Arctic coastlines. Potentially, hazardous extreme wave events are projected to become significantly more frequent and more intense. For example, in the Beaufort coastlines a once‐in‐20‐year event under the historical (1979–2005) climate is projected to occur, on average, once every 2–5 years during 2081–2100. This is a pressing issue, as it affects many Arctic coastal communities, as well as existing and emerging Arctic infrastructure and activities, with some of them having already suffered severe wave‐induced damage in the past years.
How Magnetically Conjugate Atmospheres and the Magnetosphere Participate in the Formation of Low‐Energy Electron Precipitation in the Region of Diffuse Aurora
Authors: Khazanov George V. , Glocer Alex 
Published: July 2020

AbstractThe electron precipitation in the region of the diffuse aurora should be considered as a two‐step process (Khazanov et al., 2017, https://doi.org/10.1002/2016GL072063). The first one is the interaction of plasma sheet electrons with electrostatic electron cyclotron and/or whistler waves, moving those electrons into the loss cone to precipitate in both magnetically conjugate atmospheres. The second step is the interaction of these electrons with the ionosphere and atmosphere via their elastic and nonelastic collisions and reflection (backscatter) of degraded electrons back to magnetosphere and conjugate ionospheres. This paper presents the results of a newly developed scenario of nonsteady‐state electron precipitation dynamics that accounts for magnetosphere‐ionosphere‐atmosphere energy interplay over the entire energy range of the plasma sheet electron population and their affiliated secondary electrons. It also studies how both magnetically conjugate auroral regions work together with the magnetosphere in the formation of electron precipitation in the region of the diffuse aurora with the energy range coverage from 1 eV up to 10 keV.
Improved Simulation of Monsoon Depressions and Heavy Rains From Direct and Indirect Initialization of Soil Moisture Over India
Authors: Osuri Krishna K. , Nadimpalli Raghu , Ankur Kumar , Nayak H. P. , Mohanty U. C. , Das A. K. , Niyogi Dev 
Published: July 2020

AbstractThis study investigates the impact of direct versus indirect initialization of soil moisture (SM) and soil temperature (ST) on monsoon depressions (MDs) and heavy rainfall simulations over India. SM/ST products obtained from high‐resolution, land data assimilation system (LDAS) are used in the direct initialization of land surface conditions in the ARW modeling system. In the indirect method, the initial SM is sequentially adjusted through the flux‐adjusting surface data assimilation system (FASDAS). These two approaches are compared with a control experiment (CNTL) involving climatological SM/ST conditions for eight MDs at 4‐km horizontal resolution. The surface fields simulated by the LDAS run showed the highest agreement, followed by FASDAS for relatively dry June cases, but the error is high (~15–30%) for the relatively wet August cases. The moisture budget indicates that moisture convergence and local influence contributed more to rainfall. The surface‐rainfall feedback analysis reveals that surface conditions and evaporation have a dominant impact on the rainfall simulation and these couplings are notable in LDAS runs. The contiguous rain area (CRA) method indicates better performance of LDAS for very heavy rainfall distribution, and the location (ETS > 0.2), compared to FASDAS and CNTL. The pattern error contributes the maximum to the total rainfall error, and the displacement error is more in August cases' rainfall than that in June cases. Overall analyses indicated that the role of land conditions is significantly high in the drier month (June) than a wet month (August), and direct initialization of SM/ST fields yielded improved MD and heavy rain simulations.