bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Send Me Some Pics’: Performing the Offender Identity in Online Undercover Child Abuse Investigations
Authors: Chiang Emily 
Published: September 2020

Abstract
This article presents a case study examining the performance of the offender identity in online child sexual abuse interactions between genuine suspected offenders and an undercover officer posing as an offender. Using a linguistic framework known as move analysis, the study describes and compares interactants' use of rhetorical moves, as well as move frequencies and structures. Similarities and differences in the performance of offenderness between suspected offenders and the undercover police officer are discussed. Interactions are characterised by a high level of rapport-building, sharing stories, and exchanging support. While the undercover officer largely emulates the moves of suspected offenders, key discrepancies include his comparative reluctance to engage in abuse-related story-telling and an increased tendency to inquire about abusive images. This work highlights possible target areas for police training in the task of online identity assumption in online child abuse cases.
Leptin Serum Levels are Associated With GLP-1 Receptor Agonist-Mediated Effects on Glucose Metabolism in Clozapine- or Olanzapine-Treated, Prediabetic, Schizophrenia Patients
Authors: Tomasik Jakub , Rustogi Nitin , Larsen Julie R , Jakobsen Michelle I , Svensson Camilla K , Vedtofte Louise , Jakobsen Mathilde S L , Jespersen Hans R , Koyuncu Kamuran , Schjerning Ole , Nielsen Jimmi , Ekstrøm Claus T , Correll Christoph U , Holst Jens J , Vilsbøll Tina , Bahn Sabine , Fink-Jensen Anders 
Published: September 2020

Abstract

Background
We previously demonstrated that the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide significantly reduced glucometabolic disturbances and body weight vs placebo in prediabetic, overweight, or obese schizophrenia-spectrum disorder patients treated with clozapine or olanzapine. Here, we aimed to identify potential biomarkers of prediabetes and the GLP-1RA-induced effects on glucose tolerance in schizophrenia patients treated with clozapine or olanzapine.

Methods
Multiplexed immunoassays were used to measure 8 proteins (adiponectin, C-reactive protein, interleukin-1 receptor antagonist, leptin, macrophage migration inhibitory factor, prolactin, receptor for advanced glycation end products, and vascular endothelial growth factor [VEGF]) in fasting prediabetic and non-prediabetic patients with schizophrenia-spectrum disorder, the prediabetic patients receiving 16-week randomized treatment with liraglutide or placebo.

Results
Serum adiponectin (P = .004) and VEGF (P = .019) levels were significantly lower in prediabetic (n = 81) than non-prediabetic schizophrenia-spectrum disorder patients (n = 32). Adiponectin levels increased significantly (P = .022) and leptin levels decreased significantly (P = .017) following treatment with liraglutide (n = 39) vs placebo (n = 42). Importantly, patients receiving liraglutide who had higher baseline leptin levels showed significantly larger reductions in the primary endpoint, the 75-g oral glucose tolerance test value, than patients with lower baseline leptin levels (P = .009).

Conclusion
These results provide new evidence for metabolic alterations associated with prediabetes and GLP-1RA treatment in the context of schizophrenia. They suggest that leptin may be a valuable biomarker predicting GLP-1RA-induced improvement in glucose tolerance in overweight or obese schizophrenia-spectrum disorder patients with prediabetes treated with clozapine or olanzapine. These findings require further validation in larger numbers of individuals.
Dynamics of sleep, sedentary behavior, and moderate-to-vigorous physical activity on school versus nonschool days
Authors: Armstrong Bridget , Beets Michael W , Starrett Angela , Brazendale Keith , Turner-McGrievy Gabrielle , Saelens Brian E , Pate Russell R , Youngstedt Shawn D , Maydeu-Olivares Alberto , Weaver R Glenn 
Published: September 2020

Abstract

Study Objectives
Studies examining time-use activity behaviors (sleep, sedentary behavior, and physical activity) on school days compared with nonschool days have examined these behaviors independently, ignoring their interrelated nature, limiting our ability to optimize the health benefits of these behaviors. This study examines the associations of school-day (vs. nonschool day) with time-use activity behaviors.

Methods
Time series data (6,642 days) from Fitbits (Charge-2) were collected (n = 196, 53% female, 5–10 years). We used a variable-centered dynamic structural equation modeling approach to estimate day-to-day associations of time-use activity behaviors on school days for each child. We then used person-centered cluster analyses to group individuals based on these estimates.

Results
Within-participant analysis showed that on school days (vs. nonschool days), children (1) slept less (β = −0.17, 95% CI = −0.21, −0.13), (2) were less sedentary (β = −0.05, 95% CI = −0.09, −0.02), and (3) had comparable moderate-to-vigorous physical activity (MVPA; β = −0.05, 95% CI = −0.11, 0.00). Between-participant analysis showed that, on school days, children with higher sleep carryover experienced greater decreases in sleep (β = 0.44, 95% CI = 0.08, 0.71), children with higher body mass index z-score decreased sedentary behavior more (β = −0.41, 95% CI = −0.64, −0.13), and children with lower MVPA increased MVPA more (β = −0.41, 95% CI −0.64, −0.13). Cluster analysis demonstrated four distinct patterns of connections between time-use activity behaviors and school (High Activity, Sleep Resilient, High Sedentary, and Dysregulated Sleep).

Conclusions
Using a combination of person-centered and more traditional variable-centered approaches, we identified patterns of interrelated behaviors that differed on school, and nonschool days. Findings can inform targeted intervention strategies tailored to children’s specific behavior patterns.
Acute Seizures in Cerebral Venous Sinus Thrombosis
Authors: Gazioglu Sibel , Yildirim Ahmet , Kokturk Elif G. , Seker Demet , Altunayoglu Cakmak Vildan , Velioglu Sibel K. 
Published: September 2020

Background:
Cerebral venous sinus thrombosis (CVST) often presents with acute seizures, and recurrent seizures may also be seen in the long term in some patients. The purpose of this retrospective study was to investigate the frequency and type of acute seizures and to define the risk factors.

Methods:
Sixty-two patients diagnosed with CVST between September 2007 and October 2018 were retrospectively evaluated for the occurrence of acute seizures. Seizures which developed as a presenting symptom or occurred within 2 weeks of diagnosis were defined as acute seizures. Demographic, clinical, and radiologic characteristics were compared between patients with or without acute seizures.

Results:
Twenty (32.3%) of the 62 CVST patients had acute seizures. Univariate analysis revealed a significant association between acute seizures and aphasia (P=0.03), motor deficit (P<0.001), sensory deficit (P=0.018), severe (≥3) modified Rankin Scale scores on admission (P=0.017), sagittal sinus thrombosis (P=0.037), cortical vein thrombosis (P<0.001), supratentorial lesions (P<0.001), and hemorrhagic lesions (P<0.001). Multivariate regression analysis identified supratentorial lesions (P=0.015, odds ratio: 9.131, 95% confidence interval: 1.525-54.687) and cortical vein thrombosis (P=0.034, odds ratio: 5.802, 95% confidence interval: 1.146-29.371) as independent factors for acute seizures. Although 25% of patients with acute seizures had recurrent seizures during hospitalization, only 2.6% of the 38 patients with long-term follow-up had recurrent seizures.

Conclusions:
Approximately one third of patients with CVST had acute seizures. Cortical vein thrombosis, supratentorial, and especially hemorrhagic lesions were the most significant risk factors associated with acute seizures. Although seizure recurrence may occur early in the course, long-term recurrence is rare in CVST.
Psychometric Properties of the Fibromyalgia Survey Questionnaire in Chilean Women With Fibromyalgia
Authors: Aguirre Cárdenas Carla , Oñederra Maria Cecilia , Esparza Benavente Catalina , Durán Josefina , González Tugas Matías , Gómez-Pérez Lydia 
Published: September 2020

Objective
The aim of this study was to evaluate the psychometric properties of the Chilean version of the Fibromyalgia Survey Questionnaire (FSQ).

Methods
Women with fibromyalgia (FM; n = 214), women with rheumatoid arthritis (RA; n = 97), and women without chronic pain (being followed by Gynecology, G; n = 117) from the Red de Salud UC CHRISTUS (Santiago, Chile) participated. Women with FM completed the FSQ, Fibromyalgia Impact Questionnaire (Revised Version), Numerical Pain Rating Scale, Pain Catastrophizing Scale, Pain Vigilance and Awareness Questionnaire, Patient Health Questionnaire 15, and Short-Form Health Survey. Two weeks later, they completed the FSQ again by phone (n = 120).

Results
The FSQ total scale showed excellent to good internal consistency at T1 (α = 0.91, ω = 0.91) and T2 (α = 0.78, ω = 0.78), and good test-retest reliability (intraclass correlation coefficient, 0.79; 95% confidence interval [CI], 0.72–0.85). It showed medium to large correlations with the other measures. Discriminant analysis between the FM group and the control group (RA and G) revealed that the FSQ total scale reached a classification accuracy of 81.3%. Receiver operating characteristic curve (adjusted area under the curve, 0.88; 95% CI, 0.85–0.92) showed that the best FSQ cutoff was 17, resulting in sensitivity of 89% (95% CI, 0.84–0.93) and specificity of 75% (95% CI, 0.69–0.80). Considering the FM diagnosis performed by a rheumatologist as the criterion standard, sensitivity and specificity of the modified 2010 American College of Rheumatology preliminary criteria for FM were 92.8% (95% CI, 0.88–0.96) and 63.4% (95% CI, 0.57–0.70), respectively.

Conclusions
The Chilean version of the FSQ presents good psychometric properties and is a useful tool in clinical settings to assist in FM diagnosis and symptom assessment. A cutoff score of 17 or higher seems to be the most appropriate for Chilean population.
MiREDiBase: a manually curated database of validated and putative editing events in microRNAs
Authors: Marceca Gioacchino P. , Distefano Rosario , Tomasello Luisa , Lagana Alessandro , Russo Francesco , Calore Federica , Romano Giulia , Bagnoli Marina , Gasparini Pierluigi , Ferro Alfredo , Acunzo Mario , Ma Qin , Croce Carlo M. , Nigita Giovanni 
Published: September 2020

AbstractMicroRNAs (miRNAs) are regulatory small non-coding RNAs that function as translational repressors. MiRNAs are involved in most cellular processes, and their expression and function are presided by several factors. Amongst, miRNA editing is an epitranscriptional modification that alters the original nucleotide sequence of selected miRNAs, possibly influencing their biogenesis and target-binding ability. A-to-I and C-to-U RNA editing are recognized as the canonical types, with the A-to-I type being the predominant one. Albeit some bioinformatics resources have been implemented to collect RNA editing data, it still lacks a comprehensive resource explicitly dedicated to miRNA editing. Here, we present MiREDiBase, a manually curated catalog of editing events in miRNAs. The current version includes 3,059 unique validated and putative editing sites from 626 pre-miRNAs in humans and three primates. Editing events in mature human miRNAs are supplied with miRNA-target predictions and enrichment analysis, while minimum free energy structures are inferred for edited pre-miRNAs. MiREDiBase represents a valuable tool for cell biology and biomedical research and will be continuously updated and expanded athttps://ncrnaome.osumc.edu/miredibase.
Type II collagen-positive progenitors are major stem cells to control skeleton development and vascular formation
Authors: Li Xinhua , Yang Shuting , Jing Dian , Qin Lin , Zhao Hu , Yang Shuying 
Published: September 2020

AbstractPrevious studies have revealed that type II collagen positive (Col2+) cells represent a kind of skeleton stem cells (SSC) and their descendants contribute to chondrocytes, osteoblasts, Cxcl12 (chemokine (C-X-C motif) ligand 12)-abundant stromal cells and bone marrow stromal/mesenchymal progenitor cells in postnatal life. To further elucidate the function of Col2+ progenitors, we generated mice with ablation of either embryonic or postnatal Col2+ cells. Embryonic ablation of Col2+ progenitors caused the mouse die at newborn with the absence of all skeleton except partial craniofacial bone, as well as multiple organ development defects and blood vessel loss. Postnatal ablation of Col2+ cells causes mouse growth retardation and collagenopathy phenotype. By examining Col2+ cells ablated mice, we found that, besides contributing to long bone and vertebral bone development, Col2+ cells are also involved in calvaria bone development. Meanwhile, Col2+ cells are the major cells to contribute all skeletal development including spine, rib and long bones. Moreover, our functional study provide evidence that intramembranous ossification is involved in craniofacial bone formation and long bone development, but not participates in spine development.By performing lineage tracing experiments in embryonic or postnatal mice, we discovered that the presence of Col2+ progenitors not only within the bone marrow and growth plate (GP) but also within articular cartilage. Moreover, the number and differentiation ability of Col2+ progenitors were decreased with age in long bone and knee. Furthermore, fate-mapping studies revealed that Col2+ progenitors also contributed to CD31+ blood vessel endothelial development in calvariae bone, long bone and many organs. Interestingly, we found only 25.4% CD31+ blood vessel endothelial in long bone but almost all the CD31+ blood vessel endothelial in calvariae bone are differentiated from Col2+ cells. Consistently, postnatal Col2+ cells differentiated to both chondrocytes and CD31+ blood vessel endothelial cells during bone fracture healing. Therefore, this study reveals that Col2+ progenitors are the major source of endochondral ossification, and they also contribute to vascular development in multiple organs and fracture repair.
BIM-enabled construction innovation through collaboration: a mixed-methods systematic review
Authors: Liu Hui , Skibniewski Miroslaw J. , Ju Qianqian , Li Junjie , Jiang Hongbing 
Published: September 2020

PurposeThis study aims to explore the innovative capabilities of building information modeling (BIM) in construction projects. The objectives are to construct an inclusive conceptual framework of BIM-enabled construction innovation, identify the status and trends of innovation-related research in BIM publications, synthesize research pertaining to BIM-enabled construction innovation and discover core research requirements in the related body of knowledge.Design/methodology/approachThis study proposes a comprehensive theoretical framework, named innovation pyramid, comprising context, actor, artifact, process, structure and innovative task for exploring and analyzing the innovative capability of BIM in construction projects. Accordingly, mixed methods were used to perform a systematic review of research on the topic of BIM-enabled construction innovation.FindingsThe findings reveal that BIM innovation-related articles have predominantly considered BIM as an innovation from a technological standpoint, while the innovative capabilities of BIM have remained under-researched with a fragmented research focus. Fertile grounds for research have emerged and call for research pertaining to entities of “structure” and “innovative task” as well as interaction, interrelations and mutually adjusting effect among the entities.Practical implicationsThe framework proposed may be useful for subsequent research design and for assisting project management practitioners in the use of BIM to achieve innovation more efficiently.Originality/valueThis research provides an insight into the innovative capabilities of BIM based on the BIM–collaboration–construction innovation logic chain. It contributes to the body of knowledge by devising an inclusive conceptual framework of BIM-enabled construction innovation, synthesizing the state of the art and exposing the research needs in this area.
The early growth of start-ups: innovation matters. Evidence from Italy
Authors: Fiorentino Raffaele , Longobardi Sergio , Scaletti Alessandro 
Published: September 2020

PurposeDespite the relevance of innovation in entrepreneurship literature, empirical research on the innovation-performance relationship in start-ups is underdeveloped and shows controversial results. To bridge this gap, the aim of this paper is to investigate the role of innovativeness on new venture performance in the early stage of the life cycle.Design/methodology/approachRegression modelling and propensity score matching are used to reveal systematic differences in growth between innovative start-ups (ISUPs) and non-innovative start-ups. We use an ad hoc dataset obtained through merging the financial database AIDA with data from administrative sources (Italian Chambers of Commerce and the Italian Ministry for Economic Development).FindingsThe results show that differences in growth can be explained by the different levels of innovativeness in new ventures. Moreover, unlike in prior studies, the innovation inputs matter more than innovation outputs. Indeed, the results support the idea that innovation policies can contribute to maximising the potential of start-ups.Practical implicationsThe findings provide suggestions for policy makers and entrepreneurs to help firms configure ex ante appropriate actions to support the growth of new ventures in the start-up stage.Originality/valueThis study is the first to use the new objective measure of start-up innovation, available from the Italian LD 221 register. Second, different types of innovation are investigated as antecedents of firm growth. Third, we employ propensity score matching, which favours revealing systematic differences in growth between ISUPs and non-innovative start-ups. Fourth, the results of our study are the first to offer evidence on the effectiveness of the new Italian sustaining ISUPs policy.
Where does work belong anymore? The implications of intensive homebased working
Authors: Mallett Oliver , Marks Abigail , Skountridaki Lila 
Published: September 2020

Purpose
The purpose of this paper, a “thought piece”, is to consider the everyday realities of homebased working and the implications for work during a global pandemic and beyond.

Design/methodology/approach
The authors present a conceptual framework for considering the domestic sphere as a social space and apply this framework to consider the existing evidence base on homebased working. In particular, the authors consider the implications of homebased working during and after the COVID-19 pandemic in terms of gender.

Findings
The authors identify key challenges in relation to flexibility, work intensification and socio-economic differences. Consideration of these areas highlights the potential pitfalls and challenges that are likely to persist as many organisations begin to plan for an increase in homebased working.

Originality/value
The authors argue that some commentators have been too quick to celebrate the apparent successes of the sudden, unplanned move to intensive homebased working. Important differences in occupation, gender and other socio-economic factors will have important implications for the experience of homebased working for many workers and their co-residents.
Nursing associate apprenticeship – a descriptive case study narrative of impact, innovation and quality improvement
Authors: Taylor Marion , Flaherty Cariona 
Published: September 2020

PurposeThe purpose of this article is to explore how one higher education institution (HEI) has embraced the apprenticeship agenda and is successfully providing an apprenticeship programme for nursing associates (NA) a new profession within health and social care in the United Kingdom.Design/methodology/approachThis is a descriptive case study narrative about one programme from one HEI, selected for its relevance for the subject area of apprenticeships. This descriptive approach allows the provision of apprenticeships within HEI to be explored in depth by one institution.FindingsThis case study identifies the considerable value of apprenticeships within HEI for the students, the employers and the HEI. It also identifies that there are challenges within this. These findings will be of interest to those entering into the apprenticeship arena, especially within healthcare, and may inform an academic discourse in this area.Research limitations/implicationsIt is acknowledged that this case study does not seek to compare apprenticeships with other programmes. However, there is value in providing an academic narrative around the challenges of this provision which will be informative for others developing higher apprenticeships in the United Kingdom or similar delivery of apprenticeship models internationally.Practical implicationsThere is value in providing an academic narrative around the challenges of this provision which will be informative for others developing higher apprenticeships in the UK or similar delivery of apprenticeship models internationallySocial implicationsThese findings will be of interest to those entering into the apprenticeship arena, especially within healthcare, and will inform the academic discourse in this area.Originality/valueThis is original work and provides a new body of knowledge to the inform HEIs engaging with the relatively new context of higher and degree apprenticeships, as well as the new role within healthcare of the nursing associate.
Information literacy training effectiveness on Cambodia's province-based undergraduates
Authors: Seng Cheyvuth , Carlon May Kristine Jonson Jonson , Cross Jeffrey Scott 
Published: September 2020

PurposeThis study is aimed at determining the effect of a short-term information literacy training activity on the self-efficacy of undergraduate students at province-based universities in Cambodia.Design/methodology/approachA three-week training intervention was administered to 461 undergraduate students at three province-based public universities in Cambodia. The participants answered an information literacy self-efficacy questionnaire before and after the intervention.FindingsThe students' level of information literacy self-efficacy has a low mean score of 2.23 on a five-point scale before the training. After the training, the score dramatically increased to 3.64 and was statistically significant (p-value < 0.001). This indicates that short-term information literacy self-efficacy training is an effective means to promote information literacy among students.Research limitations/implicationsThis research scope was limited to examine the effect of a short-term intervention on a particular population. Further improvements include analyzing the training effects over the long term, soliciting qualitative feedback from respondents, and gathering previous relevant training data.Practical implicationsThere is a need for a carefully designed curriculum to be implemented that focuses on introducing information and communication technology (ICT) while considering its potential application to research activity. To be able to make meaningful curriculum changes, there must be a systematic way of identifying the ICT needs that are most urgent among undergraduate students in province-based Cambodian universities.Originality/valueThis research focuses on implementing ICT training and measuring its effectiveness on Cambodian undergraduate students in province-based universities, a growing population that has immense potential in influencing the country's growth but whose information literacy self-efficacy remains largely understudied until now.