bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influenza vaccine effectiveness studies in Europe: SWOT analysis of DRIVE collaborating sites
Authors: Punzo O , Bellino S , Miller E , Salmaso S , van der Sande M , Haag M 
Published: October 2020

Abstract

Background
DRIVE is a European public-private partnership that aims at creating a network that works on high quality, brand-specific effectiveness estimates for all influenza vaccines used in the EU each season. The SWOT analysis aims at assessing the quality and feasibility of DRIVE operational model after its implementation, i.e. the operations of the study site network as applied in DRIVE.

Methods
The SWOT analysis was conducted through two meetings held among 2 of 14 partners participating in the DRIVE studies in the first season, with clinicians, nurses, data managers and lab technicians from the sites in the network. We collected data on two identified axes (1.organizational and 2.logistical, practical, and laboratory aspects), containing more than one SWOT objective. For each item classified under Strength (S), Weakness (W), Opportunity (O) or Threat (T), experts assigned a 1-5 score, meant to reflect the impact of each listed item on reaching the objectives.

Results
The most common topics, reported by both Italian and Finnish sites collaborators, were the opportunities related to the training and development of the network; funding concerns; opportunities and challenges in training the personnel; management issues due to the project practical organization (e.g. for lack of dedicated personnel, including administrative and for data entry). The scores attributed to the single items appeared skewed to the top, showing how the researchers perceived the majority of the topics as relevant for their day-to-day work.

Conclusions
The SWOT exercise was welcomed as a useful means to compare issues and practices among local study sites, but also as a chance for exchange with both peers and project lead. The results highlight the great value of communication and discussion between study groups, albeit the geographical distance. Such exercise should be included as a routine opportunity for discussion aiming at improving both collaboration and governance model in large projects.

Key messages
One of the main challenges of large public-private consortiums is building a shared governance model; opportunities for collective sharing and collaboration should be promoted in this setting. This SWOT analysis was a useful exercise that should inform the prosecution of the programming of DRIVE operational model, allowing a comparison of issues and practices among local study sites.
Measuring health outcomes of OECD countries’ urban greenspace, with a special focus on Milan (Italy)
Authors: Oradini-Alacreu A , Rebecchi A , Mezzoiuso A G , Croci R , Buffoli M , Odone A , Signorelli C , Capolongo S 
Published: October 2020

Abstract

Background
Urban world population has raised to 4.2 billion in 2018, with 2.5 billion more forecasted by 2050. Cities are places of opportunities but, at the same time, sites of environmental and social risk factors. Scientific evidence about urban green's environmental benefits is abundant, but Public Health outcomes are seldom carefully defined. The project aims at assessing the Public, Urban and Mental Health outcomes of urban green areas in Organisation for Economic Co-operation and Development (OECD) countries, and at exploring citizen urban greenspace perception in Milan, Italy.

Methods
A systematic review of literature was conducted according to the 2015 PRISMA statement. Two online databases (Medline and Embase), were consulted, and inclusion criteria were set, ruling in all OECD countries-based, English-written studies from 2000 to December 2019. Only objectively measurable health outcomes were deemed suitable for analysis. Based on the main review findings, a community-based survey was created, targeting residents of Milan and its suburban area to understand better how they benefit from the urban green areas in their city. The study is being carried out by an interdisciplinary team of medical doctors and architects.

Results
We grouped health outcomes into five separate domains, namely cardiovascular, obesity, respiratory, neoplasia and mental health. We found negative associations between disease prevalence and urban greenspace overall quantity. Size, perceived quality and accessibility were powerfully explanatory variables. Milan community-based survey drafting is underway. Results are still preliminary and will be presented by tables, graphs and plots.

Conclusions
Cities are increasingly becoming critical points for many emerging Public Health challenges. The results of our study may help urban planners, key stakeholders, policymakers and communities to preserve and increase existing green spaces, and to improve Urban Public Health.

Key messages
Urban greenspace is paramount to OECD cities’ current and future sustainability because of its significant impact on Public, Urban and Mental Health. Milan citizens show remarkable care for urban greenspaces integrity and development.
Factors associated with high-risk pregnancy: role of environmental contaminants, Brazil
Authors: Martins L , Fernandes J , Pamplona Y , Barbieri C , Vaz J , Braga A , Pereira L 
Published: October 2020

Abstract

Introduction
The Região Metropolitana da Baixada Santista (RMBS) is considered as a region with the worst maternal and child mortality rates in the state of São Paulo, Brazil. Besides this, RMBS has the worst rates of environmental contamination. High-Risk Pregnancy is one of the factors that lead to a higher chance of morbidity and mortality of the mother and fetus binomial.

Objective
Evaluate the relationship between exposure to environmental contaminants and high-risk pregnancy.

Methodology
Case-control study, using a probabilistic sample composed of 402 pregnant women divided into with and without high-risk pregnancy. The instrument used was a self-administered questionnaire and secondary data on contaminated areas obtained from the Environmental Company of the State of São Paulo. Descriptive analysis, Chi-square test, univariate and multiple logistic regression analysis were performed. The participants were also georeferenced by place of residence.

Results
It was observed an association, by chi-square test between high-risk pregnancy and age over 35 years (p &lt; 0.05), use of insecticide (p &lt; 0.001), consumption of foods packed in plastics (p = 0.050) and manipulation with oil paint (p = 0.002). The final multiple logistic regression model demonstrated that those who live in contaminated areas are 2 times more likely to have a risk pregnancy (OR = 1.993; 95%CI: 1.02; 3.90), as well as identified as jointly important risk factors for pregnancy: working in health services (OR = 3.97 (95%CI: 1.00; 16.09)), use of insecticide (OR = 3.45 (95%CI: 1.66; 7.16)) and use of oil paint (OR = 6.96 (95%CI: 1.38; 35.09)).

Conclusions
Environmental contaminants play an important role in pregnancy, and mitigating measures are needed to improve the environment and reduce high-risk pregnancy in RMBS.

Key messages
Exposure to the environmental contaminants is an important rik factor in the pregnancy. The Região Metropolitana da Baixada Santista (RMBS) is considered as a region with the worst maternal and child mortality rates in the state of São Paulo, Brazil.
Land Use Regression Model for Exposure Assessment to PM2.5 and PM10 in Rio de Janeiro, Brazil
Authors: Oliveira M , Santana M , Marques M , Griep R , Fonseca M , Moreno A , Magalhães M , Ponce de Leon A 
Published: October 2020

Abstract

Background
Air pollution is a major public health problem. The latest data from World Health Organization show that 9 out of 10 people breathe air containing high levels of pollutants and that about 4.2 million deaths were caused by exposure to fine particles in 2016. Therefore, the aim of our study was to elaborate a model for long-term exposure assessment to air pollution.

Methods
This study was developed in Rio de Janeiro city, it has 1,200.255 km² large, about 6.7 million residents and located in the southeastern region of Brazil. The information of PM2.5, PM10 and predictor variables were obtained from government agencies. The potential predictor variables have been used: temperature, relative humidity, vehicular traffic base, Census, altitude databases, vegetation cover, land use, rock masses, hydrographic and hydrographic sub-basins, urban zoning and road network. For the development of Land Use Regression models, linear regression models were specified using the supervised stepwise procedure. Cook D statistics were used to detect influential observations. The overall model performance was evaluated by leave-one-out cross validation (LOOCV).

Results
The annual mean of PM2.5 and PM10 was 11.73 (SD = ± 4.84) and 35.57 (SD = ± 8.91) μg·m−3, respectively. The R2 value in the final model for PM2.5 was 0.3812 and p-value: 0.0907. The performance evaluated by LOOCV was not also good, the RMSE was 0.2920, with R2 value of 0.1820. The R2 value in the final model for PM10 was 0.73, p-value: 0.001. The performance evaluated by LOOCV was also good, the RMSE was 0.1386, with R2 value of 0.5832.

Conclusions
The model could be applied in areas where there is no monitoring of air quality, thus, enabling the evaluation of the health impact of exposed populations, providing support for decision-making and development of public and investments policies, medium impact and long-term, more targeted in the following areas: health, environment, transportation and urban planning.

Key messages
Oswaldo Cruz Foundation. Universidade do Estado do Rio de Janeiro.
Aboriginal Human Research Ethics Committees ensuring culturally appropriate research
Authors: Finlay S , Keed V , Kelly D , Cashman M , Green S 
Published: October 2020

Abstract
Aboriginal and Torres Strait Islander people, Australia's Indigenous peoples, make up three percent of the population of Australia. Like many other Indigenous peoples in colonised countries, they suffer the worst health and social status of any population group. Australian Indigenous people have a lower life expectancy (8.6 years lower for men and 7.8 years for women) compared with other Australians (ABS 2018a). The reasons for the poorer health outcomes are complex and include historical, political and social factors (AIHW 2015a).
The health disparity has driven a high number of research projects with a focus on Australian Indigenous people or mainstream research projects where Australian Indigenous people are overrepresented. Given the uniqueness of Australian Indigenous cultures as well as the historical, political and social context, in 1998, the Aboriginal Health and Medical Research Council of New South Wales (AH&MRC) established an Australian Indigenous-specific human research ethics committee (HREC). The AH&MRC is the Indigenous peak health body of New South Wales.
This presentation will outline the role and benefit of the AH&MRC HREC as a specialised HREC. The AH&MRC HREC is fully constituted and registered under the National Health and Medical Research Council (NHMRC). The NHMRC is the leading expert body in health and medical research in Australia and develops health research guidelines. The AH&MRC HREC is one of three AHRECs in Australia. The AH&MRC Ethics Committee not only guarantees that research is conducted ethically but also ensures research involving Indigenous people is undertaken in a culturally appropriate manner. One of the key elements required by the AH&MRC is that researchers consult Indigenous communities across all stages of the project from the design, implementation, analysis and write up.
The AH&MRC HREC is essential, ensuring the research is of benefit to the Indigenous community in NSW and is conducted in a culturally safe manner.

Key messages
Specialised Indigenous human resarch ethics committees are vital to enuring research is culturally appropriate. Spscialised human resarch ethics committees can be of benefit for other disctinct populations.
The practice of plagiarism in the Faculty of medicine of Tunis: Attitudes of teacher- researchers
Authors: Bettaieb J , Cherif I , Kharroubi G , Mrabet A 
Published: October 2020

Abstract

Background
Plagiarism is a cosmopolitan scourge, which might lead to serious consequences. The Faculty of Medicine of Tunis (FMT), involved in the international accreditation process, intends to fight vigorously against plagiarism. From this perspective, the present study was undertaken and aimed to explore the positions and attitudes of FMT's faculty members towards plagiarism and the different factors influencing them.

Methods
It was a descriptive cross-sectional survey conducted among faculty members of the FMT during the academic year 2018-2019 using the validated English version of the 'Attitudes Towards Plagiarism' (ATP) questionnaire distributed online with Google forms. The ATP questionnaire consisted of 29 items divided into three factors: positive attitude, negative attitude and subjective norms towards plagiarism.

Results
A total of 340 faculty members responded to the questionnaire. Mean scores for positive attitude and subjective norms were 28.8±6.9 and 24.6±4.9 respectively, corresponding to low to moderate scores. The mean score of negative attitude was 22.4±2.6, matching a moderate score. Interpretation of these scores revealed an unfavorable attitude of the faculty members towards plagiarism and the belief that such behavior is associated with social disapproval and rejection. However, the temptation of plagiarism was palpable and self-plagiarism seemed to be tolerated. ATP scores were significantly influenced by age, grade, work experience, supervision, research activities, and English proficiency.

Conclusions
This study has pointed out the dilemma facing our faculty in its academic anti-plagiarism crusade. On the one hand, it should ensure the commitment of its faculty members and solicit their mobilization to carry on this fight, but on the other it should put in place clear disincentive policies to prevent plagiarism and cheating and apply them in an equal and transparent way between faculty members and students.

Key messages
This study showed unfavorable attitudes of Tunisian faculty members toward plagiarism. Self-plagiarism seemed to be tolerated.
Record linkage of routine data with cohorts’ data of infants under European and Portuguese law
Authors: Doetsch J , Lopes I , Redinha R , Barros H 
Published: October 2020

Abstract
The usage and exchange of “big data” is at the forefront of the data science agenda where Record Linkage plays a prominent role in biomedical research. In an era of ubiquitous data exchange and big data, Record Linkage is almost inevitable, but raises ethical and legal problems, namely personal data and privacy protection. Record Linkage refers to the general merging of data information to consolidate facts about an individual or an event that are not available in a separate record. This article provides an overview of ethical challenges and research opportunities in linking routine data on health and education with cohort data from very preterm (VPT) infants in Portugal.
Portuguese, European and International law has been reviewed on data processing, protection and privacy. A three-stage analysis was carried out: i) interplay of threefold law-levelling for Record Linkage at different levels; ii) impact of data protection and privacy rights for data processing, iii) data linkage process' challenges and opportunities for research. A framework to discuss the process and its implications for data protection and privacy was created.
The GDPR functions as utmost substantial legal basis for the protection of personal data in Record Linkage, and explicit written consent is considered the appropriate basis for the processing sensitive data. In Portugal, retrospective access to routine data is permitted if anonymised; for health data if it meets data processing requirements declared with an explicit consent; for education data if the data processing rules are complied. Routine health and education data can be linked to cohort data if rights of the data subject and requirements and duties of processors and controllers are respected. A strong ethical context through the application of the GDPR in all phases of research need to be established to achieve Record Linkage between cohort and routine collected records for health and education data of VPT infants in Portugal.

Key messages
GDPR is the most important legal framework for the protection of personal data, however, its uniform approach granting freedom to its Member states hampers Record Linkage processes among EU countries. The question remains whether the gap between data protection and privacy is adequately balanced at three legal levels to guarantee freedom for research and the improvement of health of data subjects.
Govern of conducts, risk and homeless care in Brazil: Reflections
Authors: Komoda D , Carvalho S R , Justino J , Oliveira C , Botteon L M , Dias T M , Andrade H S , Ravelli D 
Published: October 2020

Abstract
In this study, inspired by governmental studies on Foucault, Nikolas Rose, Deborah Lupton and Mitchell Dean, we develop considerations about the ways through which the concept of risk has been operating within the homeless health care that live in some metropolitan areas of Brazil. In this paper, we discuss risk us as a moral and political technology that produces patterns to experience and to analyze reality.: Risk as a technology that has an important role in governing conducts and production of subjectivity. We argue that whilst health policy determines healthy ways of life, its effect can contribute to active surveillance (by the health care experts and by the homeless persons) that stigmatizes and divide society around the concept o 'normality' informed, between others, by epidemiological 'evidence'. Albeit the risks associated with risk-based technologies to build up a surveillance net and standardization that reinforces submissive ways of life, we find out on our ethnographic study within the services - named 'Street Surgery'- that offers transdisciplinary healthcare for people living in the streets of Campinas, Brazil, that those technologies strikes itself continuously with practices of counter-conducts by the homeless that resist the normalization of their lives and point out to other ways of producing life and care. Others ways that, is important to say, have been very influential to change the medical and other professional experts practices of the 'Street Surgery' of Campinas and had been very important to academic researchers that have been questioning hegemonic discourses, arrangements and practices of care on the Primary Health System.

Key messages
Risk-based approach to health can lead to the reinforcement of submissive ways of life, incompatible with a broader concept of health. For the development of a compromised and humanized care, it's important to take into consideration the.
Food safety in canteens: a public health programme in Aveiro region (Portugal) in 2018 and 2019
Authors: Sá R , Pinho-Bandeira T , Queiroz G , Ferreira D , Lopes P , Leitão R , Pedroso M J 
Published: October 2020

Abstract

Background
Each year, 23 million people get ill from unsafe food in Europe. Food safety refers to the absence or safe acceptable levels of hazards in food that may harm the health of consumers. The Public Health Unit of Baixo Vouga Primary Healthcare Cluster (Aveiro region) developed a programme to identify hazards and promote implementation of corrective measures in community canteens that serve children and elderly. It has three fields of action: qualitative evaluation of the installation and operating conditions, based on the legislation; microbiological surveillance of food and utensils; training of food handlers and managers. This study aims to describe the results of such programme in 2018 and 2019.

Methods
This cross-sectional study used data from qualitative evaluation and microbiological results for a descriptive analysis. Additionally, an assess of the compliance of the critical points was performed to identify the main barriers in achieving the proposed targets.

Results
From a total of 420 registered canteens, 211 and 294 were evaluated in 2018 and 2019, respectively. For these years, only 87 (41.2%) and 124 (33.3%) fully complied with all critical points. The main problems were the lack of non-manual activation system in wash basins and faucets and inadequately instructed food handlers about required hygiene measures. Microbiological surveillance results of 371 and 393 samples had a proportion of satisfactory or acceptable results of: 93.5% and 91.3% for the main dish; 56.1% and 46.6% for the salads and 82.4% and 79.8% for the utensils. Coliform bacteria were the most common agent.

Conclusions
The compliances with critical points were low, accounting for the fact they are legislation-based. The microbiological results were worst for the salads' samples. Deviations give us hints of what should be reinforced. Education of the food handlers and consulting with companies to improve procedures and equipment could be of great use.

Key messages
Community canteens’ compliances with legislated criteria were low. This programme is useful in identifying vulnerabilities and may lead to the implementation of corrective measures.
Effect of weight loss on cardiometabolic risk factors in obese patients
Authors: Penesova A , Babjakova J , Havranova A , Imrich R , Vlcek M 
Published: October 2020

Abstract

Background
Central obesity and dyslipidemia are a cardinal features of the metabolic syndrome and represents increased cardiometabolic risk. It has been shown that weight loss is capable to improve insulin sensitivity and lipid parameters. The aim of our study was to analyze the effect of a weight-lowering program (diet and physical activity) on LDL- and HDL-cholesterol subfractions and cardiometabolic risk factors (waist circumference, blood pressure, insulin sensitivity, physical fitness).

Methods
We studied 2 groups of obese subjects, group A composed of 43 patients with obesity grade 1 and 2 (30F/13M; age: 43.2 ±12.4 years; BMI 31.3 ± 6.1 kg/m2); group B composed of patients with obesity grade 3 (6F/7M; age: 34.7 ±9.8 years; BMI 51.7 ± 7.9 kg/m2). The weight loss interventional program (NCT02325804) in duration of 8-week (group A) or 24 weeks (group B) consisted of hypocaloric diet and physical activity. Body composition, physical fitness, blood lipids profile (using the Lipoprint system (Quantimetrix Corp., CA, USA), and insulin sensitivity were measured.

Results
The average weight loss was 7.3±1.9 kg in group A and 35.3±16.0 kg in group B. Systolic, diastolic blood pressure (BP) as well as heart rate decreased in group A, in group B only systolic BP. Fasting plasma glucose and insulin decreased as well as insulin sensitivity and physical fitness has been improved after intervention. Total, LDL2, HDL2 cholesterol, as well as triglycerides (TG) decreased with weight in group A and total, LDL, TG, VLDL, LDL2 large, and small HDL subfractions decreased and intermediate HDL increased in group B.

Conclusions
Short term life style intervention (diet and physical activity) in patients with obesity lead to notable improvement of cardiometabolic parameters (decreased body fat mass, improved insulin sensitivity, lipid profile) as well as atheroprotective changes in LDL subfractions.

Funding
Supported by grants APVV 17-0099; VEGA 2/0129/20; VEGA 2/0072/18

Key messages
Short term life style intervention in patients with obesity lead to notable improvement of cardiometabolic parameters. Weight-lowering program (diet and physical activity) lead to positive changes in LDL- and HDL-cholesterol subfractions.