bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lampion Hias Bernilai Estetika untuk Meningkatkan Kreativitas Karang Taruna
Authors: Rochbeind Fenny , Sumarwahyudi Sumarwahyudi , Sidyawati Lisa 
Published: February 2020

Kegiatan pengabdian ini diperuntukkan bagi karang taruna dikawasan wisata Kampung Heritage Kajoetangan Kota Malang. Bertujuan untuk meningkatkan kreativitas peserta, potensi diri dibidang kreatif, menambah pengetahuan dan pengalaman artistik melalui pembuatan lampion hias. Kebutuhan akan pencahayaan dilokasi kawasan wisata bukan hanya untuk keindahan tetapi memeriahkan tampilan permukiman khususnya di malam hari. Pembekalan keterampilan bagi karang taruna sangat diharapkan dan dipastikan untuk kurun waktu tertentu, secara berkesinambungan kawasan ini menjadi sentra industri kreatif berbasis budaya lokal yang memiliki nilai ekonomis yang cukup tinggi. Masalahnya aktivitas karang taruna sangat kurang dibidang kreatif, belum memiliki kompetensi mengembangkan potensi kreatif berolah seni rupa dan kerajinan untuk memperindah lingkungan yang menjadi objek kunjungan wisata sehingga perlu dilatih. Metode yang digunakan diantaranya pengayaan, metode pembelajaran, metode partisipatif, dan metode evaluasi untuk mengetahui perubahan pengetahuan, keterampilan, dan wawasan/perilaku khalayak sasaran. Manfaat dari kegiatan pelatihan penting untuk meningkatkan kreativitas peserta, mampu berwirausaha, memiliki motivasi tinggi untuk mengembangkan potensi diri, dan menggunakan keterampilan yang dimiliki untuk memperindah, memelihara, dan melestarikan lingkungan kawasan kampung wisata Kajoetangan. Kata kunci— lampion hias, kreativitas, Kampung Heritage Kajoetangan Malang. Abstract Community service activity is for young people in the tourism area of Kajoetangan Heritage Village, Malang. Aiming to increase participant's creativity, self potential in the creative field, increase knowledge and artistic experience through making decorative lanterns. The need for lighting in the tourist area is not just for beauty but enliven the appearance of settlements, especially at night. Provision of skills for youth is highly expected and ensured for a certain period of time, this area will continuously become a center for creative industries based on local culture that has a high economic value. The problem is that the activities of the youth group are very lacking in the creative field, and do not yet have the competence to develop the creative potential to work in the arts and crafts to beautify the environment that is the object of a tourist visit so they need to be trained. The methods used include enrichment, learning methods, participatory methods, and evaluation methods to determine changes in knowledge, skills, and insights/behavior of the target audience. The benefits of the training activities are important to increase the creativity of the participants, being able to become entrepreneurs, have high motivation to develop their potential, and use their skills to beautify, maintain, and preserve the environment of the Kajoetangan tourist village. Keywords— ornamental lanterns, creativity, Kampung Heritage Kajoetangan Malang
Bir eğitim ve araştırma hastanesinde hastanesinde takip edilen Hepatit B ile enfekte gebelerin değerlendirilmesi
Authors: KAYA KILIÇ Esra , ALTUN DEMİRCAN Şerife , BULUT Cemal , ATAMAN HATİPOĞLU Çiğdem , ARSLAN Kader , KINIKLI Sami 
Published: February 2020

Amaç: Kronik hepatit B önemli bir sağlık sorunudur. İmmünoprofilaksiye rağmen, anneden çocuğa hepatit B virüs (HBV) bulaşı yüksek oranda viremi olan annelerin % 1-10' unda görülür. Gebelerin bu nedenle HBsAg pozitifliği yönünden taranması ve takibi önerilir. Bu çalışmada kliniğimizde izlenen hepatit B ile enfekte gebe kadınların yönetimi ve tedavisi değerlendirildi.Gereç ve Yöntemler: Çalışmaya 85 HBV ile enfekte gebe dahil edildi. Gebeler, gebelik süresince ve doğum sonrasında periyodik olarak takip edildi. Üç aylık aralıklarla hastaların HBV-DNA ve karaciğer fonksiyon testleri değerlendirildi. Bulgular: Hastaların yaş ortalaması 29,04±5,6 (17-38) yaş, başvuru sırasındaki gebelik haftası ortalaması 17,39±9,3 (5-38) idi. Hastaların 14’ ü (%16,4) gebelik sırasında yapılan taramalarla HbsAg pozitif olduğunu öğrendi. Gebelerin 25’inde (%29,4) Anti-HAV IgG pozitifti. Onüç hastaya (%15,3) antiviral tedavi başlandı. Onüç (%15,3) hastaya tedavi başlandı, tedavi başlanan hastaların 12’ si (%92,3) tenofovir disoproksil fumarat alırken, bir hasta telbivudin almaktaydı. Hiçbir hastada tedaviye bağlı yan etki gözlenmedi. Bebeklerin doğum sonrası takiplerinde antiviral tedavi ile ilişkili problemler izlenmedi. Takibi yapılabilen 25 (%29,4) bebeğin hiçbirinde HbsAg pozitifliği saptanmadı. Sonuç: Hepatit B bulaşında önemli bir yol olan vertikal bulaşların engellenmesi için, gebelik taramalarının ve gebelerin yakın takibinin yapılması gerekmektedir.
Envelhecimento acelerado em sementes de Mimosa tenuiflora (Willd.) Poir.
Authors: Siqueira Walter Letícia , Moreno Gabira Mônica , Nogueira Antonio Carlos 
Published: February 2020

Objetivou-se verificar a influência do envelhecimento acelerado no vigor de sementes de Mimosa tenuiflora (Willd.) Poiret. Após avaliação da biometria das sementes, estas foram submetidas a tratamento para superação de dormência, que consistiu na aplicação de água a 100 ºC durante 4 minutos. O envelhecimento acelerado foi conduzido em delineamento inteiramente casualizado, com quatro repetições de 50 sementes em cada tratamento. Os tratamentos aplicados foram de 40 ºC, 43 ºC e 46ºC em 24, 48, 72 e 96 horas de permanência na câmara de envelhecimento. O grau de umidade inicial (8,51 %) é característico de sementes ortodoxas, este valor aumentou conforme o tempo de permanência das sementes na câmara de envelhecimento. A porcentagem e o índice de velocidade de germinação apresentaram redução significativa nos tratamentos com maiores temperaturas e tempos, apesar de não haver aumento significativo do tempo médio de germinação. A frequência de germinação foi mais homogênea nos tratamentos em que as sementes foram submetidas a 40 ºC, a homogeneidade diminui com o aumento da temperatura e do tempo de permanência na câmara. Isto evidencia a redução do vigor das sementes de Mimosa tenuiflora, possivelmente devido a degradação das mesmas pelas altas temperaturas e incidência de fungos.

Palavras-chave: Germinação, caatinga, Brasil, vigor, Mimosa tenuiflora.
Roots and Wings: Indonesia´s way to improvements of women´s health care
Authors: Meerpohl Hans-Gerd 
Published: February 2020

Indonesia is the world’s fourth most populous nation and the largest economy in Southeast Asia. The World Bank recently classified Indonesia as an emerging middle-income country. Enormous gains have been made in poverty reduction, cutting the poverty rate to more than half since 1999, to 9.8% in 2018.(1) However, based on March 2017 data, approximately 20 % of the entire population remain vulnerable of falling into poverty, as their income hover marginally above the national poverty line.(2) Unique challenges for Indonesia´s health care system reflects the fact that approximately 250 million inhabitants from more than 300 ethnic groups spread over 17.000 islands. Indonesia has set itself an ambitious goal of establishing universal health care by 2019, a move commended by the United Nations as part of the 2030 Sustainable Development Goals.(SDGs) Women´s health care, including women’s empowerment and gender equality, is concerned as an especially important issue because - on a global scale- it is one area in which performance has been seen by many to be slow. (3) While Indonesia has experienced greater success in its efforts to reduce the under five mortality rate (27 per 1.000 live births in 2015), efforts to tackle maternal mortality has been less effective as rates have continued to persist above 125 per 100.000 live births over the past decade (6) Having some of those facts in my mind I started my visit to Indonesia and to Surabaya in October 2018 with the desire to understand in the end the country, the people and their health system challenges a bit better.
Optical properties of dye DN-F01 as sensitizer
Authors: Ramadhani Febrina , Supriyanto Agus , Ahmad Mohd Khairul Bin , Diyanahesa Nadiyah El-Haq , Saputri Diani Galih 
Published: February 2020

<p class="Abstract">Dye-Sensitized Solar Cell (DSSC) is a solar cell made from organic material that works with an electrochemical photo system to convert solar energy into electrical energy. The components of DSSC consist of transparent conductive substrates, dyes, semiconductors, electrolytes and counter electrodes. Dye as a sensitizer is has an important role in DSSC performance improvement. This study aims to obtain optical characterization such as absorbance spectrum and transmittance from DSSC using dye DN-F01 with concentration 2x10<sup>-3</sup> M. Optical characterization has been tested using a UV-VIS Spectrophotometer Shimadzu UV-1800. The test results show that the absorbance spectrum of the dye is at a wavelength of 400-500 nm. Band gap energy of DN-F01 has obtained from its absorbance and transmittance value is about 2,46 eV.</p>
THE IMPLEMENTATION OF RECIPROCAL TEACHING IN READING CLASS
Authors: M.Pd. Irene Trisiska 
Published: February 2020

This research was conducted to find out how the application of reciprocal teaching can improve student’s understanding in reading subject. The application of Reciprocal Teaching can help university students as prospective educators to be able to improve their creativity. This research used Classroom Action Research (CAR) which had four steps of research procedures namely planning, implementing, observing, and analyzing. The subjects of this study were fourth semester students of Kanjuruhan University of Malang who took critical reading course. To achieve the criteria for success, researchers took two cycles by adopting theories from Kemmis and Taggart. In the first cycle, students who achieved success criteria were 43.47%. However, the success criteria targeted by researchers were75%. In the second cycle the success rate of students reached 82.60%. The conclusion of this study is that teaching reading using reciprocal can increase student motivation and increase student interaction. Because interaction with other students and with lecturer increases, motivation to learn and confidence also increases, it can also improve student learning outcomes. Positive competitiveness is also shown by students bravely expressing their ideas quickly. The application of reciprocal teaching in the class has problems including controlling classroom situations, there are some students who rely on their friends in doing work, and there are some students who are a bit selfish and feel that working together in working on problems makes them slow because they have to explain their opinions and then put forward in front of the class.
Keywords: Creativity, Reciprocal Teaching, CAR
Pengaruh penambahan pati talas lokal (colocasia esculenta) sebagai stabilizer terhadap total padatan terlarut Dan kadar air yogurt pada suhu pasteurisasi 90°C
Authors: Kusumawati Aju Tjatur Nugroho , Hadiani Dimas Pratidina Puri , Fila Maria Meryana 
Published: February 2020

Penelitian ini dilakukan di Laboratorium Terpadu Fakultas Peternakan, Universitas Kanjuruhan Malang dan Laboratorium Teknologi Pangan Universitas Brawijaya Malang, pada tanggal 30 Oktober sampai tanggal 31 November 2016. Tujuan dari penelitian ini untuk mengetahui pengaruh penambahan pati talas (Colocasia esculenta) terhadap total padatan terlarut dan kadar air yogurt pada suhu pasteurisasi 90°C. Materi yang digunakan dalam penelitian ini adalah susu sapi segar, susu skim 2%, starter bakteri Lactobacillus bulgaricus dan Streptococcus thermophillus 2%, dan pati talas. Metode yang digunakan adalah percobaan Laboratorium dengan menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan yaitu penambahan pati talas P0=0%, P1=0,5%, P2=1%, P3=1,5%, masing-masing perlakuan diulang sebanyak 3 kali. Data yang diperoleh dianalisis dengan analisis ragam, apabila terdapat perbedaan maka dilanjutkan dengan uji Beda Nyata Terkecil (BNT). Variabel yang diamati meliputi total padatan terlarut dan kadar air yogurt. Hasil penelitian menunjukkan bahwa penambahan level pati talas (Colocasia esculenta) memberikan perbedaan yang sangat nyata (P<0,01) terhadap total padatan terlarut dan kadar air yogurt. Nilai total padatan terlarut yogurttertinggi pada penambahan pati talas 1,5% sebesar 21,96% kemudian berturut-turut level pati 1%, 0,5%, 0% sebesar19,69%, 18,33% dan 17,35%. Nilai kadar air yogurt pada penambahan pati talas 1,5% menghasilkan nilai terendah sebesar 77,36% kemudian berturut-turut level pati1%=80,50%, 0,5%= 81,56% dan 0% = 83,35%.
Berdasarkan hasil penelitian dapat disimpulkan bahwa penambahan pati talas sebagai stabilizer sebesar 1,5% menghasilkan kualitas yogurt yang optimal ditinjau dari total padatan terlarut dan kadar air yogurt pada suhu pasteurisasi 90°C. Disarankan adanya penelitian lanjutan untuk mengetahui kualitas yogurt dengan penambahan pati talas diatas 1,5%.
Comparative analysis of ChIP-exo peak-callers: impact of data quality, read duplication and binding subtypes
Authors: Sharma Vasudha , MAJUMDAR Sharmistha 
Published: February 2020

Abstract

Background: ChIP (Chromatin immunoprecipitation)-exo has emerged as an important and versatile improvement over conventional ChIP-seq as it reduces the level of noise, maps the transcription factor (TF) binding location in a very precise manner, upto single base-pair resolution, and enables binding mode prediction. Availability of numerous peak-callers for analyzing ChIP-exo reads has motivated the need to assess their performance and report which tool executes reasonably well for the task. Results: This study has focussed on comparing peak-callers that report direct binding events with those that report indirect binding events. The effect of strandedness of reads and duplication of data on the performance of peak-callers has been investigated. The number of peaks reported by each peak-caller is compared followed by a comparison of the annotated motifs present in the reported peaks. The significance of peaks is assessed based on the presence of a motif in top peaks. Indirect binding tools have been compared on the basis of their ability to identify annotated motifs and predict mode of protein-DNA interaction. Conclusion: By studying the output of the peak-callers investigated in this study, it is concluded that the tools that use self-learning algorithms, i.e. the tools that estimate all the essential parameters from the aligned reads, perform better than the algorithms which require formation of peak-pairs. The latest tools that account for indirect binding of TFs appear to be an upgrade over the available tools, as they are able to reveal valuable information about the mode of binding in addition to direct binding. Furthermore, the quality of ChIP-exo reads have important consequences on the output of data analysis.
The Association between Parental Migration and Early Childhood Nutrition of Left-behind Children in Rural China
Authors: Shi Huifeng , Zhang Jingxu , Du Yufeng , Zhao Chunxia , Huang Xiaona , Wang Xiaoli 
Published: February 2020

Abstract

Background: More than one-third of children under 3 years old are left behind at home due to parental migration in rural China, and we know very little about early childhood nutrition of left-behind children (LBC) because of the dearth of research. This study examined the association between parental migration and early childhood nutrition of LBC in rural China.
Methods: We used repeated cross-sectional data of rural children aged 6–35 months who participated in two surveys in six counties of northern and southern China in 2013 and 2016 respectively. The length, weight, and hemoglobin concentration were measured by trained health‑care workers blinded to parental migration status. Stunting, underweight, wasting, and anemia were identified with the standards recommended by WHO. Generalized linear regressions and multivariate logistic regressions were employed to explore the association between parental migration and these nutritional outcomes at each time point.
Results: 2,336 and 2,210 children aged 6–35 months were enrolled in 2013 and 2016, respectively. The results show a reduction of the risks of stunting, underweight, and wasting from 2013 (16.4%, 8.5%, and 3.5%, respectively) to 2016 (12.1%, 4.0%, and 1.5%, respectively) but highlight a constantly and alarmingly high risk of anemia among these children (44.8% in 2013 and 43.8% in 2016). Children with migrant fathers performed as well as or better than those with non-migrants on these indicators. Children with migrant parents performed slightly worse in 2013, but equal or slightly superior in 2016 on these indicators compared with children with non-migrants and migrant fathers. Children aged 6–17 months with migrant parents had a significantly lower risk of anemia than those living with their mothers or with both parents (43.1% vs . 63.6% and 61.5 in 2013, and 42.5 vs . 60.1% and 66.2% in 2016), even after controlling for children’s sociodemographic characteristics.
Conclusions: Parental migration may be not detrimental and even beneficial to early childhood nutrition of LBC in rural China. Continued nutritional support is needed for all rural children, especially interventions for preventing micronutrient deficiency. Programs for LBC are recommended to continue to focus on nutrition but pay more attention to other important health issues.
Dispensation of attention deficit hyperactivity disorder (ADHD) medications in patients receiving opioid agonist therapy; a national prospective cohort study in Norway from 2015 to 2017
Authors: Vold Jørn Henrik , Aas Christer , Skurtveit Svetlana , Odsbu Ingvild , Chalabianloo Fatemeh , Halmøy Anne , Johansson Kjell Arne , Fadnes Lars Thore 
Published: February 2020

Abstract
Background
It is estimated that up to a third of patients on opioid agonist therapy (OAT) have attention deficit hyperactivity disorder (ADHD). Treatment by ADHD medication, including a centrally acting stimulant (CAS) or atomoxetine is one of the essential approaches. This study evaluates the use of dispensed ADHD medications in the Norwegian OAT population in the period from 2015 to 2017. Types and doses of ADHD medications, co-dispensations of other potentially addictive drugs like benzodiazepines, z-hypnotics, gabapentinoids, and non-OAT opioids, as well as direct-acting antivirals (DAA) against hepatitis C infection, are investigated.

Methods
Information about all dispensed ADHD medication, OAT opioids, and the defined potentially addictive drugs were recorded from the Norwegian Prescription Database. Dispensation rates, the types, and the doses of dispensed ADHD medications were estimated by summarizing the number of dispensations, and the dispensed doses. Logistic regression analyses were employed to assess the associations between ADHD medication, and OAT opioid use, and dispensations of other potentially addictive drugs and DAAs against hepatitis C infection.

Results
A total of 9,235 OAT patients were included. The proportion of patients who were dispensed ADHD medication increased from 3.5% to 4.6% throughout the study period. The three most dispensed CAS were short-acting methylphenidate (55%), lisdexamphetamine (24%), and dexamphetamine (17%) in 2017. Buprenorphine, rather than methadone, as OAT opioid (adjusted odds ratio: 1.6, CI: 1.2-2.1) was associated with being dispensed ADHD medication. Among patients who received CAS and OAT opioids each calendar year, the dispensed doses of methylphenidate increased from 63 mg/day in 2015 to 76 mg/day in 2017 (p = 0.01). Sixty percent of patients receiving ADHD medications were also dispensed other addictive drugs concomitantly in 2017. Similar results were found in 2015 and 2016.

Conclusion
Co-prescription of ADHD medications was low among patients on OAT in Norway, considering a high prevalence of ADHD in this patient group. On the other hand, concurrent dispensations of multiple addictive drugs were common in this population. Understanding the underlying reasons for such prescribing is essential, and research on how to optimize ADHD medication of patients with ADHD receiving OAT is needed.
A novel virtual barcode strategy for accurate panel-wide variant calling in circulating tumor DNA
Authors: wu leilei , Deng Qinfang , Xu Ze , Zhou Songwen , Li Chao , Li yixue 
Published: February 2020

AbstractBackground Hybrid capture-based next-generation sequencing of DNA has been widely applied in the detection of circulating tumor DNA (ctDNA). Various methods have been proposed for ctDNA detection, but low-allelic-fraction (AF) variants are still a great challenge. In addition, no panel-wide calling algorithm is available, which hiders the full usage of ctDNA based ‘liquid biopsy’. Thus, we developed the VBCALAVD (Virtual Barcode-based Calling Algorithm for Low Allelic Variant Detection) i n silico to overcome these limitations. Results Based on the understanding of the nature of ctDNA fragmentation, a novel platform-independent virtual barcode strategy was established to eliminate random sequencing errors by clustering sequencing reads into virtual families.Stereotypical mutant-family-level background artifacts were polished by constructing AF distributions. Three additional robust fine-tuning filters were obtained to eliminate stochastic mutant-family-level noises. The performance of our algorithm was validated using cell-free DNA reference standard samples (cfDNA RSDs) and normal healthy cfDNA samples (cfDNA controls). For the RSDs with AFs of 0.1%, 0.2%, 0.5%, 1% and 5%, the mean F1 scores were 0.43 (0.25~0.56), 0.77, 0.92, 0.926 (0.86~1.0) and 0.89 (0.75~1.0), respectively, which indicates that the proposed approach significantly outperforms the published algorithms. Among controls, no false positives were detected. Meanwhile, characteristics of mutant-family-level noise and quantitative determinants of divergence between mutant-family-level noises from controls and RSDs were clearly depicted. Conclusions Due to its good performance in the detection of low-AF variants, our algorithm will greatly facilitate the noninvasive panel-wide detection of ctDNA in research and clinical settings. The whole pipeline is available at https://github.com/zhaodalv/VBCALAVD.