bluuebunny/crossref_metadata_2025_split huggingface dataset:
HAND GESTURE RECOGNITION FOR INDONESIAN SIGN LANGUAGE INTERPRETER SYSTEM WITH MYO ARMBAND USING SUPPORT VECTOR MACHINE
Authors: Anwar Aditiya , Basuki Achmad , Sigit Riyanto 
Published: July 2020

<p><em>Hand gestures are the communication ways for the deaf people and the other. Each hand gesture has a different meaning. In order to better communicate, we need an automatic translator who can recognize hand movements as a word or sentence in communicating with deaf people. </em><em>This paper proposes a system to recognize hand gestures based on Indonesian Sign Language Standard. This system uses Myo Armband as hand gesture sensors. Myo Armband has 21 sensors to express the hand gesture data. Recognition process uses a Support Vector Machine (SVM) to classify the hand gesture based on the dataset of Indonesian Sign Language Standard. SVM yields the accuracy of 86.59% to recognize hand gestures as sign language.</em></p><p><em><strong>Keywords</strong></em><em>: </em><em>Hand Gesture Recognition, Feature Extraction, Indonesian Sign Language, Myo Armband, Moment Invariant</em></p>
How to Improve Sharia Accountability for Sovereign Sukuk in Indonesia
Authors: Arianty Erny 
Published: July 2020

<pre><em>The</em><em> study entitled How to Improve Sharia Accountability for Sovereign Sukuk in Indonesia aims to analyze </em><em>the factor that has the highest level of importance</em><em> in realizing sharia accountability.</em> <em>The analysis of this research is conducted by applying</em><em> </em><em>Analytical Hierarchy Process (AHP) approach </em><em>with a hierarchy structure consisting of the first level, namely objectives, sharia accountability for Sovereign Sukuk/Sovereign Sharia Securities (SBSN), then the second level is shariah accountability parameters, consist of structural contract (akad) SBSN, the use of SBSN funds by maqashid sharia, and SBSN accounting and financial reporting. Each criterion is determined by sub-criteria, which are the third level. The last level is the supporting factors for the realization of sharia accountability for SBSN. </em><em>The results showed that human resources competency factor had the highest importance </em><em>level in realizing the sharia accountability for the use of the contract structure (aqad) SBSN parameter, the supervisory function factor had the highest importance level for the parameters of using SBSN funds following the shariahmaqashid, and the decision making authority factor had the highest importance level for the parameters of accounting and financial reporting. As for the results of the level of importance of the parameters, the parameter of the use of the contract structure has the highest importance level among other parameters. </em></pre>
Pengembangan Bahan Ajar SRETS (Science, Religious, Environment, Technology, And Society) Dalam Pembelajaran Biologi
Authors: . Listyono , . Kusrinah , Fitriyah Laily 
Published: July 2020

<p>Latar belakang penelitian ini karena belum adanya bahan ajar Biologi kelas XI MA/SMA dengan pendekatan SRETS <em>(S</em><em>c</em><em>ience, Religi</em><em>o</em><em>us, Environment, Technology and Society) </em>pada materi sistem imun di sekolah MA Sunniyyah Selo Grobogan. Penelitian pengembangan ini bertujuan untuk menganalisis kelayakan Bahan Ajar Biologi berpendekatan SRETS <em>(S</em><em>c</em><em>ience, Religi</em><em>o</em><em>us, Environment, Technology and Society) </em> pada materi sistem imun Kelas XI Semester Genap di MA Sunniyyah Selo Grobogan. Penelitian pengembangan ini menggunakan prosedur yang dikemukakan oleh Thiagarajan (4-D). Model ini terdiri dari 4 tahap pengembangan, yaitu <em>Define, Design, Develop dan Disseminate. </em>Setelah tahap <em>Develop </em>dilakukan pengujian kelayakan oleh ahli materi, ahli media serta guru biologi, sedangkan pengukuran aspek kognitif dilakukan dengan memberi <em>post-test</em> kemudian diuji keefektifannya dengan menggunakan uji t-test. Hasil penelitian menunjukkan bahwa bahan ajar biologi dikategorikan sangat layak untuk digunakan. Hal ini di dasarkan pada persentase 82% (ahli materi), 96,5% (ahli media) dan 87,58% (guru biologi). Tingkat respon peserta didik terhadap bahan ajar biologi dengan pendekatan SRETS mencapai 83,61% dengan kategori sangat layak digunakan. Berdasarkan uji t satu pihak diperoleh t<sub>hitung</sub>&lt; t<sub>tabel </sub>(0,2027&lt;2,045) sehinggga rata-rata nilai biologi pada materi sistem imun setelah mempelajari bahan ajar biologi berpendekatan SRETS lebih dari nilai KKM=75. Maka bahan ajar biologi berpendakatan SRETS efektif digunakan dalam pembelajaran.</p>
Penggunaan Guided Teaching Dalam Mengorganisasikan Konsep Pada Pembelajaran Sistem Peredaran Darah
Authors: Jamaludin Didi Nur 
Published: July 2020

<p align="center">Pembelajaran Biologi membutuhkan pemahaman konsep yang baik. Hasil observasi di MAN 1 Semarang, menunjukan ketuntasan belajar siswa klasikal pada materi sistem peredaran darah 67,5%. Pemanfaatan media pembelajaran terus diupayakan, namun hasilnya belum memuaskan, sehingga diperlukan penelitian untuk mengetahui efektifitas metode <em>guided teaching </em>dalam mengorganisasikan konsep pada pembelajaran sistem peredaran darah. Metode penelitian menggunakan jenis <em>weak</em><em> eksperimental design</em> tipe<em> </em><em>the </em><em>one shot case study</em><em>.</em><em> </em>Hasil penelitian diketahui bahwa rerata tingkat persentase ketuntasan kelas eksperimen mencapai 85% dengan taraf signifikansinya 0,02 dan tingkat keaktifan belajar siswa kelas eksperimen 90,81%. Berdasarkan hasil tersebut dapat disimpulkan bahwa melalui penerapan metode <em>guided teaching</em> dalam mengorganisasikan konsep efektif dapat meningkatkan ketuntasan hasil belajar dan aktifitas belajar siswa pada materi sistem peredaran darah.</p><p><strong> </strong></p><p><strong>Kata Kunci: </strong><em>Guided Teaching, </em>Organisasi Konsep, Sistem Peredaran Darah</p>
RESPON PENGENDARA BERMOTOR DAN TINGKAT KEPATUHAN TRAFFICT LIGHT TERHADAP KEBERADAAN KANOPI POHON DI PERSIMPANGAN JALAN KECAMATAN MATARAM
Authors: Sazali Munawir , Umar Amirah Muhammad , Muniri Muniri , Fahrurrozi Fahrurrozi 
Published: July 2020

Trees canopy as ecosystem services provided pleasantness activity for motorcycle rider broad daylight. This study was analysed of role thees canopy and drivers response at Mataram sub-district intersection. This study was carried out using the expost pasto approach with examining the relationship of more than one free variable (extensive and criteria of threes canopy) to the comfort and level of traffic light violations at the Mataram Sub-district intersection. Results of this study indicate that tree canopies provide a pleasantness of driving and orderly traffic lights. The tree canopy at Gubernuran intersection with shady criteria, this area of the canopy covering the entire road body has a level of comfort of motorbike riders around 74.4% with a relatively small number of violations about 95.33. Whereas the Pasar Pagutan intersection has open tree canopy criteria, the motorbike driver's pleasantness response is about 62.5% the average number of violations 177. Therefore, existence of a tree canopy around the crossroads has the effect of driving comfort thereby reducing the level of violation of traffic signs.
Initiating Global Civil Society as a Strategy for Handling the COVID-19 Public Health Threat: A Policy Review
Authors: Ayuningtyas Dumilah , Haq Hayyan Ul , Mega Utami Raden Roro 
Published: July 2020

The spread of Coronavirus Disease 2019 (COVID-19) has had a serious impact on public health. The speed and extentof its spread havedemonstrated a global failure to cultivate awareness and cooperation in responseto the threat. Therefore, in order to improve public awareness and the management of public health threats, we propose a strategy to initiate global civil society. Using Walt and Gilson's policy triangle framework for policy analysis, we reviewed and analysed a series of articles and policies related to COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the Global Health Security Agenda (GHSA), health resilience in the context of globalization, as well as other countries’ experiences. We also explored constitutional obligations, public health legislation, collaboration of civil society, and policies related to public health, as well as their implementation. Every country has its own public policy strategy for handling COVID-19. One possible solution is to expand the GHSA commitments and bind all countries that have signed the agreement to a single public policy strategy for the handling of COVID-19. The poor handling of the COVID-19 outbreak has demonstrated the need for Indonesia’s civil society collaborativelyoversee the Indonesia’s government’s implementationof its constitutional obligations. The government mustmake public health security a top priority, and collectives of educated individuals with a strong, shared vision must harness the power of non-governmental advocacy.
The Impact of Large-scale Social Restriction on COVID-19 Incidence: A Case Study of Four Regions in Indonesia
Authors: Suraya Izza , Nurmansyah Mochamad Iqbal , Rachmawati Emma , Al Aufa Badra , Koire Ibrahim Isa 
Published: July 2020

The Indonesian government has chosen to implement large-scale social restrictions, or Pembatasan Sosial Berskala Besar (PSBB), to minimize the spread of COVID-19. PSBB is a government policy aimed at restricting the internal movement of people in a bid to reduce the spread of SARS-CoV-2. This study aims to assess the impact of such large-scale social restriction measures on the incidence of COVID-19 cases in four provinces of Indonesia. Time series analysis was used to describe trends in COVID-19 cases by using surveillance data from the Ministry of Health of Indonesia. Quasi-Poisson regression with an interaction model was used to estimate the incidence rate ratio (IRR), and this was calculated to compare the incidence rate before and during PSBB implementation. The trend in COVID-19 cases in the provinces of West Java, East Java, Banten, and Jakarta has continued to fluctuate. These four provinces have continued to experience a significant increase in the COVID-19 incidence rate ratio after the implementation of the first and second PSBB periods compared to the period before PSBB implementation. Lack of proper implementation of the large-scale social restrictions has led to PSBB’s ineffectiveness in reducing the number of COVID-19 cases in each of the provinces.
Use of the product of driving pressure and respiratory rate for predicting failure of weaning from mechanical ventilator in medical patients
Authors: Gong Ju , Zhang Bibo , Huang Xiaowen , Li Bin , Huang Jian 
Published: July 2020

Abstract
Background : Respiratory workload increment in the process of mechanical ventilation withdrawal is critical for the determination of weaning outcome. Pressure, tidal volume (Vt) and respiratory rate (RR ) are considered as patient’s respiratory power, albeit being affected by excessive respiratory load. We aimed to evaluate the performance of driving pressure (DP)×RR to predict the outcome of weaning.

Methods : Plateau pressure (Pplat) and positive end-expiratory pressure tot (PEEPtot) were measured during mechanical ventilation, viz., (1) brief deep sedation, (2) on volume support ventilation of MV with Vt 6 ml/kg and a PEEP of 0 cm H 2 O, (3) Pplat and PEEPtot were measured by holding breath for 2s after inhalation and exhalation, respectively. The DP was determined as Pplat minus PEEPtot. The highest RR was recorded within 3 min during spontaneous-breathing trial (SBT). Patients that were able to tolerate SBT for 1 h were directly extubated .

Results : Out of the 61 patients studied, 22 failed weaning. During the withdrawal of ventilation, DP×RR was 134.2±33.2 cmH 2 O ·breaths/min and 238.5±61.7 cmH 2 O·breaths/min ( P =0.00), DP was 7.9±1.6 cmH 2 O and 9.7±2.3 cmH 2 O ( P =0.00), in the “success” and “failure” groups, respectively. The DP×RR index greater than 170 cmH 2 O·breaths/min had a sensitivity of 95.5% and a specificity of 89.7%, while DP index greater than 8.1 cmH 2 O had 81.8% sensitivity and 64.1% specificity to predict weaning failure.

Conclusions : Measurement of DP×RR during withdrawal of ventilation may help predict weaning outcome. Noticeably, high DP×RR increased the likelihood of weaning failure.
Cemented versus Uncemented Partial Knee Arthroplasty Trial – The CUPKAT Trial – A prospective, randomized controlled trial
Authors: Panzram Benjamin , Merle Christian , Rehnitz Christoph , Seidel-Glätzer Andrea , Bruckner Thomas , Gotterbarm Tobias , Reiner Tobias 
Published: July 2020

Abstract
BackgroundCemented Oxford unicompartmental knee arthroplasty (OUKA) has shown excellent clinical and functional long-term results as a treatment option for patients with end-stage anteromedial osteoarthritis of the knee. Despite the good long-term results that have been reported in the literature, registry data show that aseptic loosening and pain associated with the appearance of commonly seen radiolucencies around the tibial component are the most common causes for revision surgery in cemented OUKA. In order to address these problems, the cementless OUKA has been developed. Initial studies indicate excellent clinical short-term results for cementless OUKA although the risk of tibial head fracture seems to be elevated and long-term results are not yet available. Given the ongoing debate about the benefits or disadvantages of cementless fixation in knee arthroplasty, there is a need for independent level I and level II studies in order to assess the safety and equivalence of cementless OUKA in comparison to the well-documented clinical results of the cemented OUKA.Methods/DesignThis study has a prospective, randomized, controlled, double-centre, non-inferiority design. A total of 306 Patients with anteromedial OA will be randomized to cementless or cemented OUKA either at the Heidelberg University Hospital or at the Kepler University Hospital Linz. As primary outcome measure we evaluate the Oxford Knee Score (OKS) to compare clinical and functional results 2 years after cemented versus uncemented OUKA.Secondary outcome measures include clinical and functional scores as measured with the American Knee Society Score (AKSS), UCLA Activity Score, Knee Injury and Osteoarthritis Outcome Score (KOOS), Forgotten Knee Score (FJS-12), Visual Analog Pain Score (VAS), and health related quality of life questionaire (EQ-5D). In addition, complications such as the occurrence of periprosthetic fractures or implant loosening, incidence of radiolucencies and reoperation rates among others will be evaluated as secondary outcome measures and compared between the two groups. A subgroup of patients (n=150) will be asked to undergo additional radiographic DXA measurement to assess the changes in bone mineral density around the femoral and tibial components preoperatively and two years after surgery.Trials RegistrationPrior to the beginning of the clinical phase (FPI) we registered the trial at Deutsches Register Klinischer Studien (German Clinical Trials Register) with the registration number: DRKS00021303. Registered 30 April 2020. The Registration will be forwarded to the to the WHO within the next update (within the next 4 weeks) and will be searchable via its Meta-registry ( http://apps.who.int/trialsearch/ ).
Feasibility study protocol of a pragmatic, randomised controlled pilot trial: Membrane sweeping to prevent post-term pregnancy: The MILO Study
Authors: Finucane Elaine , Biesty Linda , Murphy Deirdre J , Cotter Amanda , Molloy Eleanor J , O’Donnell Martin , Treweek Shaun , Gillespie Paddy , Campbell Marian , Morrison John J. , Alvarez-Iglesias Alberto , Gyte Gill , Devane Declan 
Published: July 2020

Abstract
BackgroundPost-term pregnancy is associated with an increased risk of maternal complications, respiratory distress and trauma to the neonate. Amniotic membrane sweeping has been recommended as a simple procedure to promote the spontaneous onset of labour. However, despite its widespread use, there is an absence of evidence on a) its effectiveness and b) its optimal timing and frequency. The primary aim of the MILO study is to inform the optimal design of a future definitive randomised trial to evaluate the effectiveness (including optimal timing and frequency) of membrane sweeping to prevent post-term pregnancy. We will also assess the acceptability and feasibility of the proposed trial interventions to clinicians and women (through focus group interviews).Methods/DesignMulticentre, pragmatic, parallel group, pilot randomised controlled trial with an embedded factorial design. Pregnant women with a live, singleton fetus ≥ 38 weeks gestation, cephalic presentation, longitudinal lie, intact membranes, English speaking and ≥18 years of age will be randomised in a 2:1 ratio to:- Membrane sweep versus no membrane sweepWomen allocated randomly to a sweep will then be randomised further (factorial component) to:- early (from 39 weeks) versus late (from 40 weeks) sweep commencement; and- a single verses weekly sweepThe proposed feasibility study consists of four work packages i.e., (1) a multicentre, pilot randomised trial, 2) a health economic analysis and 3) a qualitative study (4) a study within the host trial (a SWAT).Outcomes to be collected include: recruitment and retention rates, compliance with protocol, randomisation and allocation processes, attrition rates and cost-effectiveness.Focus groups will be held with women and clinicians to explore the acceptability and feasibility of the proposed intervention, study procedures and perceived barriers and enablers to recruitment.DiscussionThe primary aim of the MILO study is to inform the optimal design of a future definitive randomised trial to evaluate the effectiveness (including optimal timing and frequency) of membrane sweeping to prevent post-term pregnancy. Results will inform whether and how the design of the definitive trial as originally envisaged should be delivered or adapted.Trial RegistrationClinicalTrials.gov, ID: NCT04307199. Registered 12th March 2020. https://clinicaltrials.gov/ct2/show/NCT04307199?id=NCT04307199&draw=2&rank=1
LncRNAs Function as Critical Metabolic Regulators in yak Liver by Integrative Transcriptome Analysis
Authors: Xia Wei , Fu Fang , Wang Li , Luo Xiaolin , Guan Jiuqiang 
Published: July 2020

Abstract
Background: The yak (Bos grunniens) is a crucial resource to supply meat and milk to the people localized in Qinghai-Tibetan plateau area. To identify lncRNAs regulating metabolism in yak, this work adopted transcriptome method to simultaneously profile mRNAs and lncRNAs of liver in yak under three representative age (LD: Liver 1 Day, LM: Liver 15 Months, LY: Liver 5 Years) conditions.Result: Of 288 differentially expressed lncRNAs, function-oriented selection yield 88 regulated metabolically related lncRNAs that were differentially expressed at least two age conditions. These lncRNAs predicted by lncRNA-mRNA correlation analysis to function in various aspects of metabolism. Selected regulations of liver metabolically related lncRNAs were further verified by qRT-PCR.Conclusion: Combining high throughput RNA-seq screening screens, bioinformatics predictions, lncRNA-mRNA correlation analysis and qRT-PCR analysis, this study supports that a class of lncRNAs function as important metabolic regulators and establishes a foundation for further investigating the role of lncRNAs in yak.
Prevalence And Predictors Of Diabetes Mellitus Among Persons Living With Hiv (Plwhiv)
Authors: UMAR DAVID MOHAMMED , NAIDOO PANJASARAM 
Published: July 2020

Abstract
Background: Diabetes mellitus is a chronic non-infectious medical condition which is evident by raised levels of glucose in the blood, because the body cannot produce any or enough of the hormone insulin or use insulin effectively. Diabetes, if not well managed leads to complications such as neuropathy, retinopathy, nephropathy which can be fatal. Some of the factors that predisposes to diabetes include older age, higher body mass index, heredity and hypertension. With the availability of HAART for the managing HIV/AIDS infection, life span of persons living with HIV (PLWHIV) has increased significantly. With increased longevity, the aging population of PLWHIV also face chronic diseases such as diabetes in addition to HIV. The burden of both HIV and diabetes is high in South Africa, particularly in KwaZulu-Natal. Nevertheless, the prevalence of diabetes among PLWHIV in KwaZulu-Natal and its predictors is not well understood. Therefore, this study was conducted to determine the prevalence, predictors of diabetes and the outcome of managing diabetes among PLWHIV.Methods: The study was conducted in four public health care facilities in KwaZulu-Natal after ethical approval and informed consent were obtained. A pretested questionnaire and hospital patient charts were used to collect data. SPSS version 26 was used to analyze the data using descriptive statistics and logistic regression. Results: The prevalence of diabetes among PLWHIV was 9%. This was higher than the prevalence of diabetes of 5.4% among the general population in South Africa. Just over 47% of those who had diabetes, had uncontrolled blood sugar, with a mean fasting blood sugar (FBS) of 11.7 mmol/L. The predictors of diabetes among PLWHIV were, male gender and older age. Male PLWHIV had 65% less chances of having diabetes and those who were between the ages of 18 and 48 years were 88% less probable to have diabetes compared to those who were older than 48 years. Conclusion: Public sector health care facilities in KwaZulu-Natal need to do much more to manage diabetes in PLWHIV in order to prevent diabetic complications and possible negative impact on the outcome of HIV management.
Knockdown of ZNF280A Inhibits Cell Proliferation and Promotes Cell Apoptosis of Bladder Cancer
Authors: He Long , Wang Xialu , Chen Peng , Du Cheng , Li Jinjiang 
Published: July 2020

Abstract
Background: ZNF280A is a member of zinc finger protein family, whose role in human cancers is little known and rarely reported. This study aimed to investigate the role of ZNF280A in bladder cancer. Methods: Immunohistochemical analysis was performed to detect the expression of ZNF280A in clinical samples. ZNF280A knockdown cell models were constructed by transfection of shRNA-expressing lentivirus. MTT assay and flow cytometry were performed for detecting cell proliferation, apoptosis and cycle. Wound healing and Transwell assays were operated to detect cell migration. Western blotting and Human Apoptosis Antibody Microarray were used to measure expression of related proteins. Mice xenograft model was constructed for in vivo study.Results: Our study demonstrated that ZNF280A was up-regulated in bladder cancer tissues compared with normal tissues, whose high expression was significantly correlated with advanced malignant grade. Knockdown of ZNF280A inhibited cell proliferation and cell migration, promoted cell apoptosis and G1/G2 phase arrest. The tumor growth in vivo was also proved to be inhibited by ZNF280A. Moreover, ZNF280A may promote bladder cancer through regulation of MAPK9, Cyclin D1 and PIK3CA. Conclusions: In this study, ZNF280A was shown as a potential tumor promotor and prognosis indicator for bladder cancer. Targeting ZNF280A may be a promising strategy for the development of novel bladder cancer treatment.