bluuebunny/crossref_metadata_2025_split huggingface dataset:
Policy and the structure of roll call voting in the US house
Authors: de Marchi Scott , Dorsey Spencer , Ensley Michael J. 
Published: March 2020

AbstractCompetition in the US Congress has been characterised along a single, left-right ideological dimension. We challenge this characterisation by showing that the content of legislation has far more predictive power than alternative measures, most notably legislators’ ideological positions derived from scaling roll call votes. Using a machine learning approach, we identify a topic model for final passage votes in the 111th through the 113th House of Representatives and conduct out-of-sample tests to evaluate the predictive power of bill topics relative to other measures. We find that bill topics and congressional committees are important for predicting roll call votes but that other variables, including member ideology, lack predictive power. These findings raise serious doubts about the claim that congressional politics can be boiled down to competition along a single left-right continuum and shed new light on the debate about levels of polarisation in Congress.
RAILWAY NATIONALISM AND «RAILWAY IMPERIALISM» IN COLOMBIA AND THE ECONOMIC DECLINE OF SANTANDER, 1907–1918
Authors: Primmer Andrew Thomas 
Published: March 2020

ABSTRACTThis article explores the development of railway nationalism and «railway imperialism» within Colombian politics during the early 20thcentury. It uses the experience of the hitherto unstudied Great Northern Central Railway of Colombia British «free-standing company» as a lens to evaluate the way in which these political currents impacted railway development in the Colombian department of Santander. It argues that the rise of railway nationalism intertwined with regionalism and personal interests represents an important and unacknowledged factor in the collapse of the British company, as well as the overall lack of railway expansion and subsequent economic decline in the department.
Complex Eyed Pockmarks and Submarine Groundwater Discharge Revealed by Acoustic Data and Sediment Cores in Eckernförde Bay, SW Baltic Sea
Authors: Hoffmann J. J. L. , Schneider von Deimling J. , Schröder J. F. , Schmidt M. , Held P. , Crutchley G. J. , Scholten J. , Gorman A. R. 
Published: March 2020

AbstractSubmarine groundwater discharge into coastal areas is a common global phenomenon and is rapidly gaining scientific interest due to its influence on marine ecology, the coastal sedimentary environment, and its potential as a future freshwater resource. We conducted an integrated study of hydroacoustic surveys combined with geochemical pore water and water column investigations at a well‐known groundwater seep site in Eckernförde Bay (Germany). We aim to better constrain the effects of shallow gas and submarine groundwater discharge on high‐frequency multibeam backscatter data and to present acoustic indications for submarine groundwater discharge. Our high‐quality hydroacoustic data reveal hitherto unknown internal structures within the pockmarks in Eckernförde Bay. Using precisely positioned sediment core samples, our hydroacoustic‐geochemical approach can differentiate intrapockmark regimes that were formerly assigned to pockmarks of a different nature. We demonstrate that high‐frequency multibeam data, in particular the backscatter signals, can be used to detect shallow free gas in areas of enhanced groundwater advection in muddy sediments. Intriguingly, our data reveal relatively small (typically <15 m across) pockmarks within the much larger, previously mapped pockmarks. The small pockmarks, which we refer to as “intrapockmarks,” have formed due to the localized ascent of gas and groundwater; they manifest themselves as a new type of “eyed” pockmarks, revealed by their acoustic backscatter pattern. Our data suggest that, in organic‐rich muddy sediments, morphological lows combined with a strong multibeam backscatter signal can be indicative of free shallow gas and subsequent advective groundwater flow.
The Space Environment of Io and Europa
Authors: Bagenal Fran , Dols Vincent 
Published: March 2020

AbstractThe Galilean moons play major roles in the giant magnetosphere of Jupiter. At the same time, the magnetospheric particles and fields affect the moons. The impact of magnetospheric ions on the moons' atmospheres supplies clouds of escaping neutral atoms that populate a substantial fraction of their orbits. At the same time, ionization of atoms in the neutral cloud is the primary source of magnetospheric plasma. The stability of this feedback loop depends on the plasma/moon‐atmosphere interaction. The purpose of this review is to describe the physical processes that shape the space environment around the two innermost Galilean moons—Io and Europa—and to show their impact from the planet Jupiter out into interplanetary space.
Guidelines and Limits for the Quantification of Ra Isotopes and Related Radionuclides With the Radium Delayed Coincidence Counter (RaDeCC)
Authors: Diego‐Feliu M. , Rodellas V. , Alorda‐Kleinglass A. , Tamborski J. , van Beek P. , Heins L. , Bruach J. M. , Arnold R. , Garcia‐Orellana J. 
Published: March 2020

AbstractThe Radium Delayed Coincidence Counter (RaDeCC) is one of the most extensively used equipment for measuring 223Ra and 224Ra activities in water and sediment samples. Samples are placed in a closed He‐circulation system that carries the Rn produced by the decay of Ra to a scintillation cell. Each alpha decay recorded in the cell is routed to an electronic delayed coincidence system which enables the discrimination of 223Ra and 224Ra. In this study, the measurement and quantification methods using the RaDeCC system are assessed through analyses of registered data in different RaDeCC systems worldwide and a set of simulations. Results of this work indicate that the equations used to correct for 223Ra and 224Ra cross‐talk interferences are only valid for a given range of activities and ratios between isotopes. Above certain limits that are specified in this study, these corrections may significantly overestimate the quantification of 223Ra and 224Ra activities (up to ~40% and 30%, respectively), as well as the quantification of their parents 227Ac and 228Th. High activities of 226Ra may also produce an overestimation of 224Ra activities due to the buildup of 222Rn, especially when long measurements with low activities of 224Ra are performed. An improved method to quantify 226Ra activities from the buildup of 222Rn with the RaDeCC system is also developed in this study. Wethus provide a new set of guidelines for the appropriate quantification of 223Ra, 224Ra, 227Ac, 228Th, and 226Ra with the RaDeCC system.
Quiet‐Time Day‐to‐Day Variability of Equatorial Vertical E × B Drift From Atmosphere Perturbations at Dawn
Authors: Zhou Xu , Liu Han‐Li , Lu Xian , Zhang Ruilong , Maute Astrid , Wu Haonan , Yue Xinan , Wan Weixing 
Published: March 2020

AbstractIonospheric day‐to‐day variability is ubiquitous, even under undisturbed geomagnetic and solar conditions. In this paper, quiet‐time day‐to‐day variability of equatorial vertical E × B drift is investigated using observations from ROCSAT‐1 satellite and the Whole Atmosphere Community Climate Model with thermosphere and ionosphere eXtension (WACCM‐X) v2.1 simulations. Both observations and model simulations illustrate that the day‐to‐day variability reaches the maximum at dawn, and the variability of dawn drift is largest around June solstice at ~90–180°W. However, there are significant challenges to reproduce the observed magnitude of the variability and the longitude distributions at other seasons. Using a standalone electro‐dynamo model, we find that the day‐to‐day variability of neutral winds in the E‐region (≤~130 km) is the primary driver of the day‐to‐day variability of dawn drift. Ionospheric conductivity modulates the drift variability responses to the E‐region wind variability, thereby determining its strength as well as its seasonal and longitudinal variations. Further, the day‐to‐day variability of dawn drift induced by individual tidal components of winds in June are examined: DW1, SW2, D0, and SW1 are the most important contributors.
Ultra-long-working-distance spectroscopy of single nanostructures with aspherical solid immersion microlenses
Authors: Bogucki Aleksander , Zinkiewicz Łukasz , Grzeszczyk Magdalena , Pacuski Wojciech , Nogajewski Karol , Kazimierczuk Tomasz , Rodek Aleksander , Suffczyński Jan , Watanabe Kenji , Taniguchi Takashi , Wasylczyk Piotr , Potemski Marek , Kossacki Piotr 
Published: March 2020

AbstractIn light science and applications, equally important roles are played by efficient light emitters/detectors and by the optical elements responsible for light extraction and delivery. The latter should be simple, cost effective, broadband, versatile and compatible with other components of widely desired micro-optical systems. Ideally, they should also operate without high-numerical-aperture optics. Here, we demonstrate that all these requirements can be met with elliptical microlenses 3D printed on top of light emitters. Importantly, the microlenses we propose readily form the collected light into an ultra-low divergence beam (half-angle divergence below 1°) perfectly suited for ultra-long-working-distance optical measurements (600 mm with a 1-inch collection lens), which are not accessible to date with other spectroscopic techniques. Our microlenses can be fabricated on a wide variety of samples, including semiconductor quantum dots and fragile van der Waals heterostructures made of novel two-dimensional materials, such as monolayer and few-layer transition metal dichalcogenides.
Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies
Authors: Ma Ying , Sun Shiquan , Shang Xuequn , Keller Evan T. , Chen Mengjie , Zhou Xiang 
Published: March 2020

AbstractDifferential expression (DE) analysis and gene set enrichment (GSE) analysis are commonly applied in single cell RNA sequencing (scRNA-seq) studies. Here, we develop an integrative and scalable computational method, iDEA, to perform joint DE and GSE analysis through a hierarchical Bayesian framework. By integrating DE and GSE analyses, iDEA can improve the power and consistency of DE analysis and the accuracy of GSE analysis. Importantly, iDEA uses only DE summary statistics as input, enabling effective data modeling through complementing and pairing with various existing DE methods. We illustrate the benefits of iDEA with extensive simulations. We also apply iDEA to analyze three scRNA-seq data sets, where iDEA achieves up to five-fold power gain over existing GSE methods and up to 64% power gain over existing DE methods. The power gain brought by iDEA allows us to identify many pathways that would not be identified by existing approaches in these data.
Quantifying contact status and the air-breakdown model of charge-excitation triboelectric nanogenerators to maximize charge density
Authors: Liu Yike , Liu Wenlin , Wang Zhao , He Wencong , Tang Qian , Xi Yi , Wang Xue , Guo Hengyu , Hu Chenguo 
Published: March 2020

AbstractSurface charge density is the key factor for developing high performance triboelectric nanogenerators (TENG). The previously invented charge excitation TENG provides a most efficient way to achieve maximum charge output of a TENG device. Herein, criteria to quantitatively evaluate the contact efficiency and air breakdown model on charge excitation TENG are established to enhance and evaluate charge density. The theoretical results are further verified by systematic experiments. A high average charge density up to 2.38 mC m−2 is achieved using the 4 μm PEI film and homemade carbon/silicone gel electrode in ambient atmosphere with 5% relative humidity. This work also reveals the actual charge density (over 4.0 mC m−2) in a TENG electrode based on quantified surface micro-contact efficiency and provides a prospective technical approach to improve the charge density, which could push the output performance of TENG to a new horizon.
An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
Authors: Broglia Laura , Lécrivain Anne-Laure , Renault Thibaud T. , Hahnke Karin , Ahmed-Begrich Rina , Le Rhun Anaïs , Charpentier Emmanuelle 
Published: March 2020

AbstractRNA degradation is an essential process that allows bacteria to control gene expression and adapt to various environmental conditions. It is usually initiated by endoribonucleases (endoRNases), which produce intermediate fragments that are subsequently degraded by exoribonucleases (exoRNases). However, global studies of the coordinated action of these enzymes are lacking. Here, we compare the targetome of endoRNase Y with the targetomes of 3′-to-5′ exoRNases from Streptococcus pyogenes, namely, PNPase, YhaM, and RNase R. We observe that RNase Y preferentially cleaves after guanosine, generating substrate RNAs for the 3′-to-5′ exoRNases. We demonstrate that RNase Y processing is followed by trimming of the newly generated 3′ ends by PNPase and YhaM. Conversely, the RNA 5′ ends produced by RNase Y are rarely further trimmed. Our strategy enables the identification of processing events that are otherwise undetectable. Importantly, this approach allows investigation of the intricate interplay between endo- and exoRNases on a genome-wide scale.
Atomic-level handedness determination of chiral crystals using aberration-corrected scanning transmission electron microscopy
Authors: Dong Zhuoya , Ma Yanhang 
Published: March 2020

AbstractHandedness or chirality determination is a challenging and important topic in various fields including chemistry and biology, as two enantiomers have the same composition and mirror symmetry related structures, but might show totally different activities and properties in enantioselective separations, catalysis and so on. However, current methods are unable to reveal the handedness locally of a nanocrystal at the atomic-level in real-space imaging due to the well-known fact that chiral information is lost in a two-dimensional projection. Herein, we present a method for handedness determination of chiral crystals by atomic-resolution imaging using Cs-corrected scanning transmission electron microscopy. In particular, we demonstrate that enantiomorphic structures can be distinguished through chirality-dependent features in two-dimensional projections by comparing a tilt-series of high-resolution images along different zone axes. The method has been successfully applied to certify the specific enantiomorphic forms of tellurium, tantalum silicide and quartz crystals, and it has the potential to open up new possibilities for rational synthesis and characterization of chiral crystals.
Unveiling reductant chemistry in fabricating noble metal aerogels for superior oxygen evolution and ethanol oxidation
Authors: Du Ran , Wang Jinying , Wang Ying , Hübner René , Fan Xuelin , Senkovska Irena , Hu Yue , Kaskel Stefan , Eychmüller Alexander 
Published: March 2020

AbstractAmongst various porous materials, noble metal aerogels attract wide attention due to their concurrently featured catalytic properties and large surface areas. However, insufficient understanding and investigation of key factors (e.g. reductants and ligands) in the fabrication process limits on-target design, impeding material diversity and available applications. Herein, unveiling multiple roles of reductants, we develop an efficient method, i.e. the excessive-reductant-directed gelation strategy. It enables to integrate ligand chemistry for creating gold aerogels with a record-high specific surface area (59.8 m2 g−1), and to expand the composition to all common noble metals. Moreover, we demonstrate impressive electrocatalytic performance of these aerogels for the ethanol oxidation and oxygen evolution reaction, and discover an unconventional organic-ligand-enhancing effect. The present work not only enriches the composition and structural diversity of noble metal aerogels, but also opens up new dimensions for devising efficient electrocatalysts for broad material systems.
Ultrafast 27 GHz cutoff frequency in vertical WSe2 Schottky diodes with extremely low contact resistance
Authors: Yang Sung Jin , Park Kyu-Tae , Im Jaeho , Hong Sungjae , Lee Yangjin , Min Byung-Wook , Kim Kwanpyo , Im Seongil 
Published: March 2020

AbstractUltra-thin two-dimensional semiconducting crystals in their monolayer and few-layer forms show promising aspects in nanoelectronic applications. However, the ultra-thin nature of two-dimensional crystals inevitably results in high contact resistance from limited channel/contact volume as well as device-to-device variability, which seriously limit reliable applications using two-dimensional semiconductors. Here, we incorporate rather thick two-dimensional layered semiconducting crystals for reliable vertical diodes showing excellent Ohmic and Schottky contacts. Using the vertical transport of WSe2, we demonstrate devices which are functional at various frequency ranges from megahertz AM demodulation of audio signals, to gigahertz rectification for fifth-generation wireless electronics, to ultraviolet–visible photodetection. The WSe2 exhibits an excellent Ohmic contact to bottom platinum electrode with record-low contact resistance (~50 Ω) and an exemplary Schottky junction to top transparent conducting oxide electrode. Our semitransparent vertical WSe2 Schottky diodes could be a key component of future high frequency electronics in the era of fifth-generation wireless communication.
Differential regulation of breast cancer bone metastasis by PARP1 and PARP2
Authors: Zuo Hao , Yang Dengbao , Yang Qiwen , Tang Haidong , Fu Yang-Xin , Wan Yihong 
Published: March 2020

AbstractPARP1 and PARP2 dual inhibitors, such as olaparib, have been recently FDA approved for the treatment of advanced breast and ovarian cancers. However, their effects on bone mass and bone metastasis are unknown. Here we show that olaparib increases breast cancer bone metastasis through PARP2, but not PARP1, specifically in the myeloid lineage, but not in the cancer cells. Olaparib treatment or PARP1/2 deletion promotes osteoclast differentiation and bone loss. Intriguingly, myeloid deletion of PARP2, but not PARP1, increases the population of immature myeloid cells in bone marrow, and impairs the expression of chemokines such as CCL3 through enhancing the transcriptional repression by β-catenin. Compromised CCL3 production in turn creates an immune-suppressive milieu by altering T cell subpopulations. Our findings warrant careful examination of current PARP inhibitors on bone metastasis and bone loss, and suggest cotreatment with CCL3, β-catenin inhibitors, anti-RANKL or bisphosphonates as potential combination therapy for PARP inhibitors.
Plate-nanolattices at the theoretical limit of stiffness and strength
Authors: Crook Cameron , Bauer Jens , Guell Izard Anna , Santos de Oliveira Cristine , Martins de Souza e Silva Juliana , Berger Jonathan B. , Valdevit Lorenzo 
Published: March 2020

AbstractThough beam-based lattices have dominated mechanical metamaterials for the past two decades, low structural efficiency limits their performance to fractions of the Hashin-Shtrikman and Suquet upper bounds, i.e. the theoretical stiffness and strength limits of any isotropic cellular topology, respectively. While plate-based designs are predicted to reach the upper bounds, experimental verification has remained elusive due to significant manufacturing challenges. Here, we present a new class of nanolattices, constructed from closed-cell plate-architectures. Carbon plate-nanolattices are fabricated via two-photon lithography and pyrolysis and shown to reach the Hashin-Shtrikman and Suquet upper bounds, via in situ mechanical compression, nano-computed tomography and micro-Raman spectroscopy. Demonstrating specific strengths surpassing those of bulk diamond and average performance improvements up to 639% over the best beam-nanolattices, this study provides detailed experimental evidence of plate architectures as a superior mechanical metamaterial topology.
Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila
Authors: Deng Patricia , Khan Anzer , Jacobson Dionna , Sambrani Nagraj , McGurk Leeanne , Li Xianghua , Jayasree Aswathy , Hejatko Jan , Shohat-Ophir Galit , O’Connell Mary A. , Li Jin Billy , Keegan Liam P. 
Published: March 2020

AbstractADAR RNA editing enzymes are high-affinity dsRNA-binding proteins that deaminate adenosines to inosines in pre-mRNA hairpins and also exert editing-independent effects. We generated a Drosophila AdarE374A mutant strain encoding a catalytically inactive Adar with CRISPR/Cas9. We demonstrate that Adar adenosine deamination activity is necessary for normal locomotion and prevents age-dependent neurodegeneration. The catalytically inactive protein, when expressed at a higher than physiological level, can rescue neurodegeneration in Adar mutants, suggesting also editing-independent effects. Furthermore, loss of Adar RNA editing activity leads to innate immune induction, indicating that Drosophila Adar, despite being the homolog of mammalian ADAR2, also has functions similar to mammalian ADAR1. The innate immune induction in fly Adar mutants is suppressed by silencing of Dicer-2, which has a RNA helicase domain similar to MDA5 that senses unedited dsRNAs in mammalian Adar1 mutants. Our work demonstrates that the single Adar enzyme in Drosophila unexpectedly has dual functions.
Downsizing of animal communities triggers stronger functional than structural decay in seed-dispersal networks
Authors: Donoso Isabel , Sorensen Marjorie C. , Blendinger Pedro G. , Kissling W. Daniel , Neuschulz Eike Lena , Mueller Thomas , Schleuning Matthias 
Published: March 2020

AbstractDownsizing of animal communities due to defaunation is prevalent in many ecosystems. Yet, we know little about its consequences for ecosystem functions such as seed dispersal. Here, we use eight seed-dispersal networks sampled across the Andes and simulate how downsizing of avian frugivores impacts structural network robustness and seed dispersal. We use a trait-based modeling framework to quantify the consequences of downsizing—relative to random extinctions—for the number of interactions and secondary plant extinctions (as measures of structural robustness) and for long-distance seed dispersal (as a measure of ecosystem function). We find that downsizing leads to stronger functional than structural losses. For instance, 10% size-structured loss of bird species results in almost 40% decline of long-distance seed dispersal, but in less than 10% of structural loss. Our simulations reveal that measures of the structural robustness of ecological networks underestimate the consequences of animal extinction and downsizing for ecosystem functioning.