bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rehabilitation of the Worn Dentition With Direct and Indirect Minimally Invasive Concepts—A Systematic Review and Meta‐Analysis
Authors: Chantler Jennifer G. M. , Pirc Miha , Strauss Franz J. , Rohr Nadja , Thoma Daniel S. , Ioannidis Alexis 
Published: December 2024

ABSTRACTObjectiveTo report and compare the survival of minimally invasive direct and indirect restorations of different materials for restoring the worn dentition.Material and MethodsA systematic search was conducted in six databases: MEDLINE, Web of Science, Scopus, CENTRAL, VHL, and EMBASE. The eligibility criteria of this systematic review used the PICO framework to address the following research question: “In dentate patients with a worn dentition (P), does rehabilitating their lost tooth structure with indirect restorations (I) or direct (C) effect the survival and success of treatment (O)?”. Study characteristics, survival rates of the restorations were extracted from each article. No language restrictions were applied. Survival and prevalence estimates were calculated using random‐effect models.ResultsThe electronic search yielded 5009 entries, resulting in 14 publications selected for full‐text analysis. These included 2 RCTs, 7 prospective, and 5 retrospective studies, with a varying level of methodological quality. This included 52% direct and 48% indirect restorations, using varying materials and follow‐up periods. The survival of direct composite resin restorations versus indirect manually processed composite resin restorations showed no significant difference (n = 2; OR, 1.79 [95% CI, 0.64–5.05]; p = 0.270). For the prospective articles, the pooled prevalence estimates of the survival restorations were; direct (n = 3; 99% [95% CI, 0.97–1.00]) and; indirect (n = 5; 100% [95% CI, 0.99–1.00]). Lithium disilicate recorded the least amount of failures at 1.8%.ConclusionsAlthough the survival estimates of indirect manually processed and direct composite resins were not significantly different, indirect restorations—especially those made of lithium disilicate ceramic—may offer better survival rates, compared to direct resin restorations in patients with worn dentition.Clinical SignificanceDespite the limited evidence, indirect ceramic restorations appear to be well‐suited for long‐term treatment of worn dentition, whilst direct composite resin restorations are more suited as an medium‐term solution.
First Report of ‘Soft Flesh’ Induced by the Parasite Kudoa thyrsites (Myxosporea) in Commercial Codfish From Norway
Authors: Giulietti Lucilla , Levsen Arne , Bao Miguel , Karlsbakk Egil , Storesund Julia E. , Tung Hui‐Shan , Cipriani Paolo 
Published: December 2024

ABSTRACTKudoa thyrsites is a myxosporean parasite that infects the skeletal muscle of various teleost fish species globally. Severe infections lead to ‘soft flesh’ in fish fillets, resulting in food spoilage and subsequent discard. While K. thyrsites has previously been identified in migratory Atlantic mackerel in the northern Northeast Atlantic Ocean, it has not been observed in resident or farmed fish species in Norwegian waters until now. This study presents the first evidence of K. thyrsites infection and the associated ‘soft flesh’ condition in resident commercially important gadoid species from Norwegian waters, including Norwegian coastal cod (NCC), Northeast Arctic cod (NEA) and tusk. Molecular analyses confirmed the parasitic infection in ‘soft flesh’‐affected fish sampled from multiple coastal locations in Norway. The life cycle of Kudoa remains unknown but likely involves an alternating annelid host as in other myxosporeans. These findings in resident hosts suggest that the parasite completes its life cycle also at higher latitudes, in northern Norway. Consequently, there is a risk for the Norwegian fishing industry, as the effect of the parasite on fish fillet texture can occasionally occur and impact both consumer acceptance and industry revenues.
Intraspecific Variation in Reproductive Aspects of Female Soldier Crabs, Mictyris guinotae, Between the River Mouth and Upper Reach Habitats
Authors: Jinno Masaki , Doi Wataru , Mizutani Akira , Kohno Hiroyoshi 
Published: December 2024

ABSTRACTThe soldier crab, Mictyris guinotae, is a dominant intertidal crustacean associated with sand flats in the vicinity of the Urauchi River estuary on Iriomote Island, Japan. We compared various aspects of its reproductive biology at two sites (the river mouth and upper reach) on exposed bare sand flats 300 m and 3000 m upstream from the mouth. Bimonthly sampling was conducted between November 2010 and April 2011. The abundance of female crabs was higher at the mouth of the river. Female individuals had significantly larger body sizes (approximately 1.5 times larger carapace length) in the upper reaches. Despite the low presence of ovigerous females in the upper reach site, their larger body size led to the release of a substantial number of larvae per individual, although fewer larvae were produced per day than by females at the river mouth. The breeding period, as inferred from the occurrence of ovigerous females, persisted from December to March. At the upper reach site, the duration was slightly shorter, with an earlier peak. Variations in larval release timing may compensate for fluctuations in recruitment success.
TmCOP1‐TmHY5 module‐mediated blue light signal promotes chicoric acid biosynthesis in Taraxacum mongolicum
Authors: Liu Qun , Wu Zhiqing , Qi Xiwu , Fang Hailing , Yu Xu , Li Li , Chen Zequn , Wu Jie , Gao Yugang , Kai Guoyin , Liang Chengyuan 
Published: December 2024

SummaryChicoric acid, a phenolic compound derived from plants, exhibits a range of pharmacological activities. Light significantly influences the chicoric acid biosynthesis in Taraxacum mongolicum; however, the transcriptional regulatory network governing this process remains unclear. A combined analysis of the metabolome and transcriptome revealed that blue light markedly enhances chicoric acid accumulation compared to red light. The blue light‐sensitive transcription factor ELONGATED HYPOCOTYL5 (HY5) is closely associated with multiple core proteins, transcription factors and chicoric acid synthase genes involved in light signalling. Both in vivo and in vitro experiments demonstrated that TmHY5 directly regulates several chicoric acid biosynthetic genes, including TmPAL3, Tm4CL1 and TmHQT2. Additionally, TmHY5 promotes the accumulation of luteolin and anthocyanins by increasing the expression of TmCHS2 and TmANS2. The E3 ubiquitin ligase CONSTITUTIVELY PHOTOMORPHOGENIC 1 (COP1) forms a protein complex with TmHY5, significantly inhibiting chicoric acid biosynthesis. Blue light inhibits TmCOP1‐TmHY5 complex protein formation while enhancing the expression levels of TmCOP1 through TmHY5. Furthermore, TmHY5 elevates the expression levels of TmbZIP1, which indirectly activates Tm4CL1 expression. In vivo, TmCOP1 directly inhibits the expression of the TmHY5‐Tm4CL1 complex. Therefore, we speculate that TmCOP1‐TmHY5‐mediated blue light signalling effectively activates chicoric acid biosynthesis, providing a foundation for the application of blue light supplementation technology in industrial production.
MdLRR‐RLK1‐MdATG3 module enhances the resistance of apples to abiotic stress via autophagy
Authors: Chen Wenjun , Guo Wei , Zhang Chao , Zhao Yi , Lei Yingying , Chen Cui , Wei Ziwen , Dai Hongyan 
Published: December 2024

SUMMARYApple is an important economic species affected by abiotic stress, such as salt and drought. LRR‐RLKs play a key role in plant responses to stress, although their physiological functions under abiotic stress are not yet fully understood. Autophagy is a highly conserved process in eukaryotes, which plays a vital role in drought and salt stress responses. In this study, overexpression of MdLRR‐RLK1 in apple promoted plant growth and development and increased salt and drought stress tolerance. MdLRR‐RLK1 interacts with MdATG3 in vivo and in vitro, and MdATG3 ubiquitinates and degrades MdLRR‐RLK1. Intriguingly, MdLRR‐RLK1 and MdATG3 enhance salt and drought tolerance through increasing autophagy. Moreover, MdATG3 interacts with MdATG8F and MdATG8I‐like in apple. These findings reveal the interaction between MdLRR‐RLK1 and MdATG3, suggesting mechanisms that regulate apple growth and resistance to abiotic stress.
La regla de interpretación ‘contra stipulatorem’. Repercusión de las estipulaciones ambiguas, oscuras y dudosas en el contrato de seguro
Authors: Jaramillo J. Carlos Ignacio 
Published: December 2024

A tono con el deseo de examinar uno de los temas que, en nuestro entender, revisten mayor actualidad, pertinencia y valía, y que sin hesitación encarna uno de esos ‘grandes temas del seguro contemporáneo’ -y del contrato, en general-, nos anima el deseo de ocuparnos de la temática concerniente a la interpretación del contrato de seguro. Y, en particular, referida a una de las más empleadas reglas en la contemporaneidad, no exenta de estimulante controversia en cuanto a su ubicación, naturaleza, aplicación, requisitos, modus operandi y límites, no siempre, empero, cabalmente observados.

Nos referimos, en efecto, al significado de la regla, canon, directriz o pauta hermenéutica, conocida de diversas maneras, pero en especial como regla contra stipulatorem (contra el que estipula), contra proferentem (contra el que predispone), in dubio pro consumatore o pro consumatoris (la duda en favor del consumidor), y en lo individual y más específico, in dubio pro asegurado (la duda en favor del asegurado), sin soslayar otras denominaciones, algo más generales y abarcadoras: regla o ‘principio’ pro consumatore, y pro asegurado, todas enlazadas por elementos comunes y vertebrales que, con la venia del lector, nos proponemos seguidamente auscultar.
Para dicho propósito, por traducirse en un aspecto neurálgico de la anunciada temática, igualmente analizaremos la repercusión -o las secuelas- de las estipulaciones ambiguas, oscuras y dudosas en el ámbito del contrato de seguro, paradigmático en la esfera dogmática y en la judicial.
Comprehensive Life Cycle Analysis of Diverse Hydrogen Production Routes and Application on a Hydrogen Engine
Authors: Accardo Antonella , Gentilucci Gaia , Spessa Ezio 
Published: December 2024

Abstract
In the effort of achieving net-zero greenhouse gas (GHG) emissions, hydrogen is becoming increasingly relevant in several sectors such as automotive, cogeneration, maritime, off-road, and railroad. However, hydrogen can be produced from different routes involving different production processes and feedstocks. Contrarily to the key role of hydrogen in the transport sector's decarbonization, publications that claim to address the environmental impacts of hydrogen are often focused on global warming potential (GWP). This paper focuses on the environmental impacts of hydrogen production considering different production routes (i.e., steam methane reforming (SMR), SMR with carbon capture and storage (CCS), coal gasification (CG), CG with CCS, and electrolysis from fossil fuels and from renewables) and a broad set of environmental indicators. The life cycle assessment (LCA) methodology is applied in the present study with a twofold aim. The first aim is to develop the LCA models of diverse hydrogen production routes and address present and potential well-to-tank (WTT) impacts. The second aim is to apply the previous findings to develop a cradle-to-grave LCA of a hydrogen engine, serving as a case study for the automotive sector. The LCA models are developed using simapro v.9.4.0.3 as LCA software and ecoinvent v3.8 as background database. The functional units are 1 kg of hydrogen for the cradle-to-gate boundary and 1 mile of vehicle lifetime for the cradle-to-grave boundary. The traci 2.1 method developed by the U.S. Environmental Protection Agency (EPA) is used.
On the Use of Tension Transition Zones for Kinematic and Compliance Performance Analysis of Wire-Actuated Continuum Robots
Authors: Shihora Neel , Lawson Jared , Moubarak Paul , Reese Maximilian , Wang Long , Simaan Nabil 
Published: December 2024

Abstract
Wire-actuated/tendon-actuated mechanisms suffer from discontinuity in their performance measures stemming from the limitation of unilateral actuation due to tendon actuation (pull-only actuation). Using traditional Jacobian-based performance measures ignores these limitations and can underestimate the expected position/orientation (pose) uncertainty for a given design. In this paper, we put forth the notion of wire-tension transition zones, and we illustrate how these tension transition zones can be used to modify the definition of the traditional Jacobian when calculating the expected robot performance in terms of dexterity, end-effector pose uncertainty and compliance. We use wire-actuated continuum robots as an illustrative robot architecture. We compare the expected performance of three-wire versus four-wire designs while considering somewhat realistic design parameters drawn from surgical robotics as an application domain. The results of our simulation studies emphasize the importance of carefully using the reduced Jacobin with tension transition zones to capture the performance measure discontinuities due to wires/tendons going slack. Furthermore, the results show that the traditional approach underestimates the uncertainty in the position of the end-effector by as much as 50% (effects of joint-level uncertainty) and 206% (compliance performance analysis) in the case of a three-wire design alternative. We believe that this contribution supports medical robotic system designers in architecture selection and comparative design performance analysis while avoiding unpleasant surprises that would otherwise be encountered if traditional performance measures were used.
Roughness Effects on Dense-Gas Turbine Flow: Comparison of Experiments and Simulations
Authors: Gloerfelt Xavier , Hake Leander , Bienner Aurélien , Matar Camille , Cinnella Paola , aus der Wiesche Stefan 
Published: December 2024

Abstract
This article presents a combined numerical and experimental study of the high-subsonic organic vapor flow in a linear turbine cascade. The profile geometry is the well-documented LS59 highly loaded rotor blade and the working fluid is Novec649, a dense gas used in organic Rankine cycles. Large eddy simulations are carried out with and without the roughness introduced by the additive manufacturing process. The results for the rough blade are in fair agreement with experiments, while the smooth surface induces a change in the vortex shedding regime. A detached shedding, characterized by a long recirculation downstream of the trailing edge and a base pressure plateau, is obtained in the experiments and by discretizing the roughness in the simulation. By contrast, a transonic vortex shedding is established when the surface is smooth: intense vortices roll up immediately after the trailing edge, yielding a short bubble and a lattice of shock waves. A strong pressure drop is observed at the trailing edge, resulting in high profile losses. In both cases, the boundary layer is turbulent ahead of the separation, but its thickness is significantly greater in the rough configuration, which may be the reason for the change of regime.
An Oversized Pipeline: a Potential Solution for Seamlessly Integrating Intermittent Green Hydrogen Production and Low Carbon Fuel Synthesis
Authors: Dinata Randy , Li Guohua , Prewitt Thomas Joseph , Flechas Tatiana , Finneran Shane 
Published: December 2024

Abstract
This paper explores the challenges and solutions associated with integrating intermittent electrolytic hydrogen production from variable electricity sources, such as wind and solar farms, into chemical processes requiring steady hydrogen feedstock (e.g., ammonia synthesis process). Focusing on a hypothetical scenario closely resembling actual project requirements in the industry, the study evaluates three design options for hydrogen storage and transportation. Design Option 1 utilizes oversized pipelines, leveraging pipeline packing/unpacking mechanism, while Design Option 2 involves on-site storage of hydrogen in pressurized storage tubes co-located with the electrolyzer plant. Design Option 3 incorporates a Battery Energy Storage System (BESS). This study shows that the use of both Design Option 1 and 2 can be both technically and economically feasible. In Design Option 1, the cyclical nature of pipeline pressure and its impacts on pipeline integrity in hydrogen environment must be assessed, which vary based on project-specific requirements such as hydrogen production trend, supply rate, and pipeline size. In Design Option 2 the process risks concerns related to the number of storage tubes and connections required must be evaluated, including the potential radius of impact in the event of failures leading to uncontrolled releases of hydrogen gas. Design Option 3, on the other hand, would incur a substantially higher project cost compared to the other two aforementioned options and hence was not evaluated further.
Performance and Suitability of Design-Phase Bedrock Excavatability Assessment in Pipeline Construction
Authors: Toussaint Luc , Ghazali Rami , Baumgard Alex 
Published: December 2024

Abstract
Excavations can be readily advanced in most soils by digging while bedrock often requires ripping, hydraulic hammering, or blasting. Excavation effort, or excavatability, is therefore an important factor in planning the execution of projects and estimating costs. In this case study, estimates from a design-phase excavatability assessment conducted for a pipeline alignment routed through sedimentary rocks of the Canadian Cordillera are compared to actual construction observations including blasting records. Discrepancies and possible associated causes are then discussed, and considerations for future work are offered.
Investigation of Fracture Toughness Behavior for Carbon Steel Line Pipes Under Hydrogen and CO2 Environment
Authors: Kuo Chih-Hsiang , Newbury Brian , Baker David , Li Chong , Nissley Nathan , Noecker Fredrick , Hoyt Douglas , Jun Hyun Jo , Thirumalai Neeraj 
Published: December 2024

Abstract
Within the global effort to reach carbon emission targets, low carbon hydrogen production and CO2 capture, and sequestration are two crucial focus areas for energy transition. Pipelines are expected to play a critical role in the energy transition as transportation systems of hydrogen and CO2. For hydrogen pipelines, sufficient fracture toughness is one of the key design requirements in ASME B31.12. Further, blue hydrogen production requires capturing CO2 after steam methane reforming and transporting to an underground sequestration site. However, the impact of residual H2 within dense phase/supercritical CO2 has not been broadly studied In this investigation, API 5L sour grade (PSL2 + annex H) and non-sour grade (PSL2) carbon steel line pipes (X65 amdX70) were tested to evaluate the fracture toughness values under (1) 100% H2 at 2400 and 3600 psi and, (2) a mixture of 99% CO2 and 1% H2 at a total pressure of 2400 psi. All measured fracture toughness results were above the ASME B31.12 required fracture toughness value (55 MPa-m1/2). Critically, initiation toughness values were observed to be near-identical between experimental conditions, indicating a strong effect of hydrogen even at low concentrations. The present study underscores the need for detailed experimentation to study the effect of residual-low hydrogen concentrations on the mechanical properties of common transmission pipeline materials.
Energy Consumption Prediction Method of Oilfield Gathering System Based on Multi-Level Covariates
Authors: Liu Jiaquan , Hou Lei , Zhang Xinru , Zhu Zuoliang , Wang Mincong , Wang Wenjun 
Published: December 2024

Abstract
The oilfield gathering system converts electric energy and chemical energy from fuel into kinetic energy and thermal energy from fluids through rotating equipment and the heat exchanger, which is the main part of the energy consumption of the oilfield. To control the increase in energy consumption, it is necessary to predict the energy consumption in the future of the system. With the advancement of oilfield digitalization, data-driven intelligent prediction methods have received widespread attention due to their ability to effectively extract hidden features from energy consumption data. The data are analyzed to generate multiple covariates, including data from multiple pipeline network nodes and data from the union plant. The energy consumption prediction method based on multi-level covariates is proposed. Aiming at gas consumption prediction in an oilfield union plant, multivariable features are extracted from multi-level historical and future covariates by the recurrent neural network. The experimental results of actual production data show that the gas consumption in the gathering system can be predicted accurately. The proposed method can make full use of the collected multivariable data to achieve energy consumption prediction, which is helpful for oilfield staff to take pre-stage measures to achieve energy consumption reduction.
Quantifying Corrosion Patterns: A Study of Corrosion Clustering Around Elevation Valleys With a Large Inline Inspection Dataset
Authors: Fadic Anton , Murray Michael 
Published: December 2024

Abstract
Elevation valleys are suspected to play a role in pipeline corrosion. One proposed mechanism is water and solids accumulation at these valley locations, which play a role in combination with other variables such as flowrate and pipe geometry, among others. From our literature review no studies have been published that show the relationship between valley locations and corrosion anomalies using real world inspection data at large scale. This topic has been researched rather indirectly, typically by the study of water accumulation in simulated settings, using two immiscible fluids of different densities, frequently using a combination of some sort of oil and water. These studies are not designed to analyze corrosion effects on the pipe, limiting their ability to predict and quantify where corrosion is more likely to occur, which is a critical aspect of pipeline maintenance.
In this paper we examine corrosion clustering around valley locations using inline inspection (ILI) data originated from operating pipelines, which supports the causality path of corrosion assisted by water accumulation at valley locations. We quantify statistically significant excess corrosion count density (CCD) for each assessment by comparing elevation valleys to non-valley locations and to local elevation maxima (peaks). A permutation method gives the likelihood of randomly observing the valley corrosion density at non-valley locations. We studied 1,083 ILI assessments of 557 pipeline systems, totaling 28,067 assessment miles, and 11,834 miles of independent systems transporting crude oil. A strong association between elevation valleys and significant excess corrosion density was demonstrated in several pipeline systems. Peaks did not show a statistically significant correlation. For assessments with over 100 corrosion counts, the corrosion density was found to be up to 18 times higher at valleys than the rest of the assessed system, and 44% of the systems had at least one assessment that presented a significant pattern of corrosion clustering around valleys.
The stability of the generated signal was studied over time for systems with multiple assessments, confirming the consistency of the results. The consistency of this metric applied to a large dataset justifies its use as an indicator of anomalous internal corrosion in a system, potentially helping pipeline operators to identify systems that are or may soon be affected by excess internal corrosion.