bluuebunny/crossref_metadata_2025_split huggingface dataset:
Une mission catholique en mutation
Authors: Turiano Annalaura 
Published: November 2019

Résumé
Les décennies 1950-1960 constituent un tournant pour les multiples sociétés missionnaires implantées en Égypte depuis le XIXe siècle. De nombreuses missions se retirent du pays pour laisser la place à des Églises qu’ elles ont elles-mêmes contribué à créer. D’ autres ordres parviennent, au prix de plusieurs réajustements, à assurer leur présence. Cet article interroge les restructurations à l’ œuvre dans une mission italienne – la mission salésienne – et la manière dont elle relève le défi de l’ arabisation. Au-delà des stratégies d’ adaptation d’ une mission catholique dans l’ Égypte nassérienne, cet article propose une réflexion sur l’ évolution des formes et des contenus de l’ action missionnaire durant deux décennies.
Sit-and-wait prey: first field observations of scorpions preying on antlions (Neuroptera)
Authors: Segev Nitzan , Gavish-Regev Efrat , Berger-Tal Oded 
Published: November 2019

Abstract
Antlions (Neuroptera) are a group of sit-and-wait predator insects, with some species further specializing in digging conical pit-traps in the ground in order to catch prey. Studies on antlions’ predators are scarce with only few generalist predators known to feed on them. Here we report for the first time on field observations of antlions’ predation by three scorpion genera. We suggest that scorpions may be common predators of antlions, at least in the hyper-desert environment of southern Israel. The effects of predation risk on the behavior of sit-and-wait and particularly on trap-building predators received little attention in the literature. In light of our observations, we posit that predation risk must be taken into serious consideration in future research of antlions in particular, and sit-and-wait predators in general.
Validity and Reliability of the Reflux Sign Assessment
Authors: Lechien Jérôme R. , Rodriguez Ruiz Alexandra , Dequanter Didier , Bobin Francois , Mouawad Francois , Muls Vinciane , Huet Kathy , Harmegnies Bernard , Remacle Sarah , Finck Camille , Saussez Sven 
Published: November 2019

Objective: To develop and validate the Reflux Sign Assessment (RSA), a clinical instrument evaluating the physical findings of laryngopharyngeal reflux (LPR). Methods: A total of 106 patients completed a 3-month treatment based on the association of diet, pantoprazole, alginate, or magaldrate with the LPR characteristics (acid, nonacid, mixed). Forty-two asymptomatic individuals completed the study (control group). The RSA results and reflux finding score (RFS) were documented for the LPR patients at baseline and after treatment. Intrarater reliability was assessed through a test-retest blinded evaluation of signs (7-day intervals). Interrater reliability was assessed by comparing the RSA evaluations of three blinded otolaryngologists through Kendall’s W. Responsiveness to change was evaluated through a comparison of the baseline and 3-month posttreatment findings. The RSA cutoffs for determining the presence and absence of LPR were examined by receiver operating characteristic (ROC) analysis. Results: A total of 102 LPR patients completed the study (68 females). The mean age was 53 years. The mean RSA at baseline was 25.95 ± 9.58; it significantly improved to 18.96 ± 7.58 after 3 months of therapy ( P < .001). RSA exhibited good intra- ( r = 0.813) and interrater (Kendall’s W = 0.663) reliabilities (N = 56). There was no significant association between the RSA, gastrointestinal endoscopy findings, and the types of reflux (acid, nonacid, or mixed) according to impedance-pH monitoring. An RSA >14 may be suggestive of LPR. Conclusion: The RSA is a complete clinical instrument evaluating both laryngeal and extralaryngeal findings associated with LPR. The RSA demonstrated high intra- and interrater reliabilities and responsiveness to change.
The application of Six Sigma to perform quality analyses of plasma proteins
Authors: Yang Fumeng , Wang Wenjun , Liu Qian , Wang Xizhen , Bian Guangrong , Teng Shijie , Liang Wei 
Published: November 2019

Background The Six Sigma theory is an important tool for laboratory quality management. It has been widely used in clinical chemistry, haematology and other disciplines. The aim of our study was to evaluate the analytical performance of plasma proteins by application of Sigma metric and to compare the differences among three different allowable total errors in evaluating the analytical performance of plasma proteins. Methods Three different allowable total error values were used as quality goals. Data from an external quality assessment were used as bias, and the cumulative coefficient of variation in internal quality control data was used to represent the amount of imprecision during the same period. Sigma metric of analytes was calculated using the above data. The quality goal index was calculated to provide corrected measures for continuous improvements in analytical quality. Results The Sigma metric was highest using the external quality assessment standards of China: it was sigma ≥6 or higher in 57.1% of plasma proteins. But Sigma metric was lower by using RiliBÄK or biological variation standards. IgG, C3 and C-reactive protein all required quality improvements in imprecision. A single-rule 13s for internal quality control was recommended for IgA, IgM, C4 and rheumatoid factor, whereas multiple rules (13s/22s/R4s) were recommended for IgG, C3 and C-reactive protein, according to the external quality assessment standards of China. Conclusions Different quality goals can lead to different Sigma metric for the same analyte. As the lowest acceptable standard in clinical practice, the external quality assessment standard of China can guide laboratories to formulate reasonable quality improvement programmes.
Development and Scoring of a Survey on Public Health Accreditation Capacity
Authors: Whittington Melanie D. , Atherly Adam J. , Chen Li Wu , VanRaemdonck Lisa , Lampe Sarah 
Published: November 2019

Objectives: Public health accreditation is a 7-step process that starts with a period of preapplication during which a health department assesses its readiness for accreditation. However, no tools with established reliability and validity that quantitatively measure a local health department’s (LHD’s) capacity for accreditation are available to complete this initial step. We developed and validated a survey to measure accreditation capacity for LHDs. Methods: From January through April 2015, we administered a cross-sectional electronic survey instrument with 15 questions that tapped into domains of capacity for public health accreditation. We analyzed and grouped responses by using a confirmatory maximum likelihood factor analysis with oblique rotations. We assessed reliability by using Cronbach α, and we assessed validity by comparing responses with previously established instruments. We administered the survey to 174 LHD directors in Colorado, Kansas, and Nebraska, 153 (88%) of whom responded. Results: The factor analysis produced a 3-factor model of accreditation capacity, suggesting that accreditation capacity depends on 3 distinct latent constructs: support for accreditation, preparation, and planning and approach. The model had good scale reliability (average Cronbach α = 0.7) and validity (average factor correlation = 0.43). Conclusions: The survey developed and scored in this analysis can be used by LHDs to inform the feasibility of initiating the time-intensive and costly process of accreditation.
Make Your Move Experience: A Worksite Wellness Pilot in South Texas
Authors: Wilkinson Anna V. , Davé Amanda , Ozdemir Elif , Rodriquez Limairy , Reininger Belinda M. 
Published: November 2019

Purpose: To describe the implementation of Make Your Move Experience (MYME) between 2015 and 2017. Design: Cross-sectional. Setting: Make Your Move Experience is a culturally sensitive worksite wellness program in South Texas designed to encourage sedentary workers to engage in physical activity. Participants: In total, 681 individuals from 19 different organizations. Intervention: UTHealth School of Public Health in Brownsville staff recruited individuals within local organizations to join MYME. At the end of the 3 months, organizations in which employees met MYME goals earned an incentive—bike rack or hydration station—selected to be permanent features of the local environment and facilitate physical activity. Measures: Participant self-reported gender, physical activity level prior to joining MYME (beginner or experienced), and weekly miles of biking, walking, or running completed. Analysis: Mean number of miles biked, walked, and ran each month were compared between (1) beginners and experienced, (2) men and women, and (3) in fall 2016 and spring 2017 using t tests. Results: Beginners initiated physical activity by walking. Men biked more miles than women did ( P < .05 all 3 years). Bike riders cycled fewer miles (20.2 miles vs 44.9 miles; P = .03) and walkers covered fewer miles (195.4 miles vs 266.7 miles; P = .04) in fall 2016 compared to spring 2017. Conclusions: Participation in MYME, a culturally appropriate intervention delivered at the worksite, facilitated an increase in physical activity levels among sedentary individuals.
Assessment of the Impact of Clinical Pharmacology Consultations Provided to Hospital Clinicians From the Drug Information Center—An Outcome Research in a Developing Country
Authors: Harish CVN , Belavigi Devaraj , Patil Amol N. , Pattanaik Smita , Kakkar Ashish , Kasudhan Kripa Shankar 
Published: November 2019

Background: Drug Information Center (DIC) with on-call evidence-based medicine service can revolutionize health-care practice and also can play a major role in health-care delivery in both developed and developing countries. Objective: To assess the feedback received from hospital clinicians for the newly initiated DIC services in a tertiary care hospital of North India. Methods: This is a retrospective cohort study conducted between January 1, 2016, to December 31, 2018. The clinicians approached DIC for specific pharmacotherapeutic questions for managing an index patient. After providing consultation, DIC followed up with them for the action taken and feedback on the consultation. The results of the data analyzed using Fisher Exact test and descriptive statistics. Results: Of 264 encounters, more than 98% of clinicians found the service satisfactory. There was a statistically significant association between the timely answer provided to treating physicians and their level of satisfaction with the service ( P < .05). There was no significant association between academic experiences and the satisfaction or dissatisfaction among the clinical fraternity colleagues. The interpretation ability of on-call pharmacology postgraduate students was a significantly associated factor with clinician’s satisfaction level ( P < .05). More than 96% of clinicians followed the pharmacotherapy advice recommended by DIC in their patient management. Conclusion: Thorough evaluation of published research needs to be taught to budding pharmacologists, pharmacists in their curriculum for an effective DIC service. DIC service has the potential to minimize the barrier of evidence-based medicine practice in developing as well as developed countries.
HIV care in Istanbul, Turkey: How far is it from the UNAIDS 90–90–90 targets?
Authors: Mete Bilgul , Gunduz Alper , Bolukcu Sibel , Karaosmanoglu Hayat K , Yildiz Dilek , Koç Meliha M , Aydın Ozlem A , Dokmetas Ilyas , Tabak Fehmi 
Published: November 2019

The prevalence of human immunodeficiency virus (HIV) infection is low but it is steadily increasing in Turkey. In the current study, we aimed to assess the status of HIV infection management with the proposed 90–90–90 targets in a large HIV cohort in Istanbul, Turkey. The cohort included 2382 patients (2082 male, 300 female, mean age was 36.3 ± 11.3 years). Mean CD4 cell count was 399 cells/mm3 and HIV-RNA level was 576,235 copies/ml. According to the modeling by the Modeling tool of European Center for Diseases Control Software, 72 and 74% of all HIV patients had been diagnosed in 2016 and 2017, respectively (the first target). Among 2382 patients, 2191 (92%) were on antiretroviral therapy (the second target). The third target of virally suppressing those on treatment was achieved among 70.2% of the patients. The current study suggests that both the fraction of those living with undiagnosed HIV and the proportion of those on treatment who are virally suppressed should be targeted to sustain optimal HIV care. Efforts should continue to surpass the targets of 90–90–90.
Kinematic Analysis of Smiles in the Healthy Pediatric Population Using 3-Dimensional Motion Capture
Authors: Hallac Rami R. , Thrikutam Nikhitha , Chou Pang-Yun , Huang Rong , Seaward James R. , Kane Alex A. 
Published: November 2019

Introduction: Facial normalcy, as measured with 2-dimensional or 3-dimensional photographs, has been documented in the healthy pediatric population. However, static images convey far from a complete representation of an individual’s daily interactions with peers. Craniofacial surgery induces changes to soft or osseous tissues and thereby affects dynamic facial expression. To-date, there has not been rigorous, dynamic quantification of normal facial expression. In this study, we used 4-dimensional (4D) imaging to assess the facial expression of healthy children to provide a normative reference point for craniofacial surgeons. Methods: A total of 36 healthy pediatric volunteers underwent 4D video recordings while performing a maximal voluntary smile. A face template containing 884 landmarks was registered and tracked throughout the videos using Dimensional Imaging software. Participants were divided into 2 smile groups: open-lip smile and closed-lip smile. Kinematic analysis of smiles was calculated for every landmark from its position in the resting frame to its terminal displacement. Results: Composite smiles and Euclidean distance maps were generated displaying areas of greatest displacement near the oral commissures. There was significant difference between closed-lip and open-lip groups in regions of eyes and cheeks. In addition, the open-lip smile group demonstrated significantly greater displacement in the oral commissure on the left side compared to the right ( P < .05); whereas, in the closed-lip group, the eyes and cheeks moved significantly more on the right side. Conclusion: This study presents an innovative method that can be used to evaluate facial expressions to help craniofacial surgeons restore functional movement in patients with facial anomalies.
An incremental model of second language speech production mechanisms: Developmental evidence from object ellipsis in second language Chinese speech production
Authors: Yuan Boping , Zhang Lulu 
Published: November 2019

Aims: This study investigates object ellipsis in English and Korean speakers’ second language (L2) Chinese speech production and the effects of first language (L1) influence in L2 Chinese speech production. Design: 59 English speakers and 64 Korean speakers at various Chinese proficiency levels, as well as 16 native speakers of Chinese, participated in the study. In addition to an acceptability judgement test, an utterance-recall task was employed in the study to prime participants for relevant structures. Findings: There are early stages where derivations, such as move, deletion, etc., are not implemented in L2 speech production, although at later stages L2 speech production mechanisms can converge with that of native speakers. No evidence of L1 influence is found, and L2 learners are found to behave differently in the utterance-recall task and the sentence acceptability judgement task. Originality: The study includes data from L2 Chinese learners from beginner to advanced levels and provides a comprehensive picture of structural priming effects on the development of L2 speech production. Implications: There is a discontinuity in the development of L2 speech production mechanisms, and the development of the mechanisms is incremental in nature. Mechanisms for L2 language comprehension are different from those for L2 speech production, at least as far as L2 at the early stages is concerned.
Cannabinoid receptor 2 agonist promotes parameters implicated in mucosal healing in patients with inflammatory bowel disease
Authors: Tartakover Matalon Shelly , Ringel Yehuda , Konikoff Fred , Drucker Liat , Pery Shaul , Naftali Timna 
Published: November 2019

BackgroundCannabis benefits patients with inflammatory bowel disease (IBD). Cannabinoid receptors are expressed in gut immune cells and in epithelial cells of inflamed guts. Mucosal healing (MH) requires epithelial layer restoration.ObjectiveTo analyze the effects of CB2 agonist on parameters implicated in gut inflammation and MH.MethodsMucosal samples from areas of inflamed/uninflamed colon from 16 patients with IBD were cultured without/with cannabinoid receptor 2 (CB2) agonist (JWH‐133, 10 µM, 6 hours (hr)), and analyzed for epithelial/stromal cell proliferation, apoptosis (secretome matrix metalloproteinase 9 (MMP9) activity, which impairs epithelial permeability) and interleukin‐8 (IL‐8) levels (n  = 5–9). In addition, Caco‐2 (colon carcinoma epithelial cells) were cultured with biopsy secretomes (48 hr), and analyzed for phenotype and protein markers of proliferation (proliferating cell nuclear antigen), autophagy (LC3IIB) and permeability (Zonula occludens‐1) (n  = 4–6).ResultsUninflamed tissue had higher epithelial proliferation (Ki67: 50%↑, p  < 0.05), and reduced secretome MMP9 activity and IL‐8 levels (>50%↓, p  < 0.05) compared to inflamed tissue. Treatment with CB2 agonist had no effect on epithelial apoptosis, but increased epithelial Ki67 expression (25%), and reduced secretome MMP9 and IL‐8 levels in inflamed biopsies. Secretomes of CB2‐treated biopsies increased Caco‐2 number, migration, proliferating cell nuclear antigen and LC3IIB expression (all, p  < 0.05), but had no effect on ZO‐1.ConclusionUsing ex vivo and in vitro human models, we demonstrated that manipulating the cannabinoid system affects colon cells and secretome characteristics that facilitate MH in IBD.
Interventions to Improve Clinical Outcomes in Indigenous or Remote Patients With Chronic Kidney Disease: A Scoping Review
Authors: Ovtcharenko N. , Thomson B. K. A. 
Published: November 2019

Background: Chronic kidney disease (CKD) associates with a significant health care burden with a disproportionate impact on indigenous persons or people living in remote areas. Although screening programs have expanded in these communities, there remains a paucity of evidence-based interventions to enhance clinical renal outcomes in these populations. Objective: The objective of this study was to identify evidence-based interventions to enhance renal outcomes in these populations. Design: A scoping review was conducted for studies in the Cochrane, MEDLINE, and Embase databases and from major nephrology meetings. Setting: Chronic kidney disease, including those on dialysis. Patients: Remote or indigenous populations Measurements: Studies that performed an intervention that was followed by measurement of renal outcomes or patient-centered outcomes (ie, quality of life) were included. Methods: All studies were described by study type, intervention, and clinical outcome, and trends were identified by both authors. Meta-analysis was not conducted due to study heterogeneity. Results: Thirty-two studies met inclusion criteria, only 2 (6.3%) of which were randomized controlled trials. Intervention types included multidisciplinary (34.4%), satellite (32.3%), telehealth (25.0%), or other (9.4%). All multidisciplinary interventions were performed in the CKD (non-dialysis) setting and reported improved patient travel time, waiting time, quality of life, kidney function, proteinuria, and blood pressure. Telehealth interventions improved program cost, patient attendance, hospitalization, and quality of life. Satellite interventions were performed in the hemodialysis setting, with 1 study evaluating acute hemodialysis. Satellite interventions improved patient travel time, dialysis clearance, quality of life, and survival, but increased program costs. Limitations: The study was restricted to interventional trials assessing clinical outcomes and to studies in developed countries, which likely excluded some research contributing to this field. Conclusions: There is significant heterogeneity among studies of interventions for patients with CKD who are indigenous or live remotely. Interventions were more likely to be successful when the remote or indigenous community was included in program development, with a culturally safe approach. More large, high-quality studies are needed to identify effective interventions to enhance clinical renal outcomes in indigenous or remote populations. Trial Registration: This trial is registered under PROSPERO, Registration Number 128453.
ABO blood group distributions in multiple sclerosis patients from Basque Country; O- as a protective factor
Authors: Lopetegi Itziar , Muñoz-Lopetegi Amaia , Arruti Maialen , Prada Alvaro , Urcelay Sabin , Olascoaga Javier , Otaegui David , Castillo-Triviño Tamara 
Published: November 2019

Background The relation between ABO/Rh groups and multiple sclerosis (MS) has been proposed in several studies, however there is a controversy about the role of these groups in the disease. Although it has been reported that some groups can be protective or risk factors, there is no consensus and discordant reports can be found in the literature. Objectives and methodology In this short report, we analyze the ABO/Rh distribution in a MS cohort of 265 patients and compare these frequencies with the results obtained from the Basque Blood Donors bank (17,796 individuals) of the same region. Results and conclusions From our data, the absence of immune antigens (A, B or Rhesus +) defined by the group O- seems to be protective in the MS group with an odds ratio of 0.49 (95% confidence interval 0.309–0.796), while the presence of Rh+ plus A or B seems to be a risk in developing multiple sclerosis.