bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pediatric Sepsis Phenotype in a Single-Center Cohort Covering 2010–2020: Evolution in Day 1–Day 3 Trajectory and Potential Prognostic Value
Authors: Aldewereld Zachary , Horvat Christopher , Clermont Gilles 
Published: February 2025

Objectives:
To examine the utility of day 3 sepsis phenotype classifications compared with day 1 and whether these could be reliably identified using routine clinical data on day 1.

Design:
Retrospective cohort study of pediatric patients managed 2010–2014 and 2018–2020.

Setting:
Academic children’s hospital.

Patients:
One thousand eight hundred twenty-eight children (1 mo to 18 yr old) admitted to the PICU with suspected infection who received a minimum of 7 days of systemic antibiotics.

Interventions:
None.

Measurements and Main Results:
Subjects showed significant evolution of phenotype from day 1 to day 3, with 31.7–60.9% remaining the same type. Outcomes were worst in those classifying as type D on day 3, with mortality as high as 16.6% in those that were classified as type D on both days 1 and 3, as well as 11.3% in those initially classified as type C (a lower mortality type) on day 1 but type D on day 3. Accurate statistical prediction of day 3 types using multinomial logistic regression and random forest and day 1 data was poor, despite attempts to improve performance.

Conclusions:
In our retrospective cohort of patients with sepsis, we identified significant evolution in phenotype over the first 3 days of illness. Day 3 phenotypes may provide more accurate statistical prediction of outcomes, but identification of day 3 phenotypes using data available early in the course of illness is challenging. New methods will likely be required to improve performance in this area.
Research on adaptive nonlinear dynamic inversion fault-tolerant flight control system based on sideslip trim strategy
Authors: Li Kecheng , Shi Jingping , Liu Xiaoxiong , Zhu Hongyuan , Wang Lei 
Published: February 2025

Purpose
Loss of control and air crashes are frequently caused by aircraft faults. Therefore, a practical control strategy can prevent aircrafts from losing control without control laws reconstruction. The purpose of this paper is to propose a sideslip trim fault-tolerant control strategy for wing damage and aileron stuck.

Design/methodology/approach
The six degree of freedom model of the damaged aircraft is constructed by using the non-center-of-mass approach on the basis of aerodynamic database, which is calculated in XFlow. This paper adopts the sideslip command for trim, combining with the adaptive nonlinear dynamic inversion control to achieve fault-tolerant control.

Findings
This strategy can effectively improve the control margin of the remaining control surface and guarantee maneuverability of the aircraft after serious faults.

Originality/value
The original and wing-damaged aircraft models are reconstructed in CATIA, and the aerodynamic data is calculated in XFlow. Sideslip angle is adopted to compensate additional roll moment caused by wing damage or aileron stuck. Adaptive nonlinear dynamic inversion control, combined with sideslip trim, is applied to achieve fault-tolerant control.
Users’ privacy behaviors in response to WhatsApp policy changes
Authors: Elciyar Kemal 
Published: February 2025

Purpose
After the changes in its privacy policies, WhatsApp has faced serious backlash from its users, with opinions and posts suggesting boycotts and a shift toward alternative applications becoming prominent. However, research on this reaction after the policy change might create in usage practices is quite limited. This study aims to investigate user decision-making in the dynamic landscape of mobile technologies, focusing on the factors influencing users’ choices between continuing with their current platform and migrating to alternatives.

Design/methodology/approach
Using migration theory and the push–pull mooring (PPM) model, the research identifies push factors (institutional privacy concerns), pull factors (relative privacy protection) and mooring factors (switching costs and exhaustion) as collectively shaping WhatsApp usage continuity.

Findings
Notably, the research highlights that institutional privacy concerns surprisingly do not significantly impact users’ intentions to persist with WhatsApp. Conversely, the relative privacy protection of an alternative platform emerges as a significant pull factor, influencing users’ intentions. Switching costs, particularly replacement and evaluation costs, exert a robust mooring effect, hindering migration and contributing to switching exhaustion. Results suggest that heightened exhaustion further strengthens the intention to persist with the current platform.

Originality/value
This research contributes to the literature by presenting findings that resonate with traditional migration approaches, offering a nuanced perspective on users’ decision-making processes. It delves into the impact of exhaustion on users’ intentions to continue using a platform, as well as the aftermath of policy changes, shedding light on switching dynamics and privacy concerns in reactive processes.
Organizational citizenship behaviour roles in the energy transition: a narrative review from a Malaysian perspective
Authors: Abu Bakkar Mohd Faiz , Jaaffar Amar Hisham , Abd Majid Nurshahirah 
Published: February 2025

Purpose
This study aims to review recent conceptualizations and theories of organizational citizenship behaviour (OCB) and its role in the energy transition from Malaysia’s perspective. It examines how factors of OCB, such as individual values, attitudes, motivations, leadership style, organizational culture and policies, affect the energy transition process. The research findings have implications for future studies on energy transition, highlighting the role of OCB in shaping the country’s strategies, addressing challenges and contributing to the transition process.

Design/methodology/approach
This study conducts a narrative review of past literature and documents OCB in the context of energy transition; factors influencing OCB (individual, organizational and external factors); OCB in the context of energy transition; and insights into energy transition in Malaysian organizations.

Findings
This study finds support in the literature for the impact of OCB on energy transition efforts from the Malaysian perspective. OCB, which extends beyond formal role expectations, can significantly support the effective implementation of energy policies and contribute to organizational objectives. By encouraging OCB within organizations, Malaysia can facilitate the adoption of renewable energy and energy efficiency practices, thereby playing a crucial role in reducing dependence on fossil fuels and advancing the energy transition, instilling hope for a more sustainable future.

Originality/value
This study encourages future research to explore the relationship between discussed variables and their impact on OCB, which is crucial for organizational policies aimed at advancing the energy transition in Malaysia. These findings contribute to the growing body of knowledge on OCB within the context of energy transition and provide a foundation for further related research.
Recycle signs and recycling shopping behaviour in retail stores
Authors: Nguyen Dung Trung , D’Souza Clare 
Published: February 2025

PurposeThe waste crisis in Australia exacerbates in the household sector, urging local councils and retailers/manufacturers to improve consumers’ recycling shopping behaviour – the most relevant touchpoint to the whole recycling process. In retail stores, packaging recyclability is communicated by either the central route (symbols/signs) or the peripheral route (packaging colours/materials); however, how the effects are differentiated and how the central route can be emphasised for a long-term attitudinal change are unclear. The research investigates these issues by applying the elaboration likelihood model (ELM).Design/methodology/approachA total sample of 420 respondents were recruited across Australia and managed online by Qualtrics. The data were analysed by using structural equation modelling with AMOS 29 software.FindingsBoth routes of processing are significant as per the model. Furthermore, the perceived argument quality of recyclable packaging signs mediates the effect of recycling consideration on consumers’ semiotic knowledge, enhancing attitudinal change via central processing. Recycling considerations display negative effects on recycling shopping behaviour.Originality/valueThis research theoretically contributes by extending the ELM with the newly proposed concepts of semiotic knowledge and symbols’ argument quality, further explaining consumers’ processing of information on packaging recyclability. From a practical perspective, the research provides valuable contributions for both policymakers and retailers by showing how central processing can be emphasised for a more sustainable attitudinal change to enhance recycling shopping behaviour.
Critical categories of nostalgia and their negative impact on green manufacturing intentions for processed food products
Authors: Hama Kareem Jamal Ahmed , Muhammad Farooq Hussain 
Published: February 2025

PurposeThe main purpose of the current study is to get a better understanding of how the set of crucial categories of nostalgia can negatively impact on green manufacturing intentions in the food industry field, taking three food factories as a case study.Design/methodology/approachBoth qualitative and quantitative data were collected using semi-structured interviews and a questionnaire to fulfill the study’s objectives. The questionnaire has previously undergone testing.FindingsThe study results showed that nostalgia categories, especially personal nostalgia, significantly hinder the intention to create green manufacturing system requirements. This, in turn, reduces the intention to produce green products and, consequently, to buy and consume them by an audience that is dominated by nostalgia traits.Originality/valueThis paper’s originality enables the introduction of a brand-new contribution in terms of providing sponsoring facts and information, which goes a long way toward filling the gap in the literature regarding the essential effect that can be achieved by way of the set of nostalgia categories. This includes using a modern look inside the inexperienced manufacturing intentions for processed food products. The current study focused on food sector factories in the Iraqi Kurdistan Region to accomplish this goal.
Changes in disorder and fear of crime in a disadvantaged neighbourhood following the implementation of a BID organisation
Authors: Di Rocco Jennie , Kronkvist Karl , Vasiljevic Zoran , Ivert Anna-Karin 
Published: February 2025

Purpose
The purpose of this paper is to examine changes in disorder and fear of crime in a disadvantaged neighbourhood following the implementation of a Business Improvement District (BID) organisation, a collaborative initiative designated to improve a defined geographical area.

Design/methodology/approach
A mixed-method design was used. The quantitative data was collected through an annual community survey with four pre-implementation and five post-implementation waves. Also a comparison area was included. The qualitative data was comprised of interviews with key informants in the community, which were completed before the organisation commenced its work and then again six years later.

Findings
Survey results revealed a reduction in disorder and fear of crime. This trend, albeit smaller, could be seen in the comparison area as well. Key informants further corroborated the reduction in disorder and fear of crime, attributing many of the neighbourhood changes to the organisation’s work.

Originality/value
This study is the first to evaluate whether BIDs can affect perceived disorder and fear of crime, relevant factors affecting crime levels and community well-being. Furthermore, it illustrates the benefits of using a comprehensive study design suitable for accounting for changes in a setting where it is difficult to isolate effects.
Dengue dynamics in Bali: Serotype shifts, genotype replacement and multiple virus lineage circulation in the last 10 years
Authors: Sasmono R. Tedjo , Masyeni Sri , Hayati Rahma F. , Rana Bunga , Santoso Marsha S. , Denis Dionisius , Hansen Diana S. , Morita Kouichi 
Published: February 2025

AbstractBackgroundBali, one of the world's most popular tourist destinations, is hyper‐endemic to dengue, an acute febrile illness caused by infection with dengue virus (DENV). Outbreaks of dengue occur annually with worrisome rates of morbidity and mortality. Despite this, comprehensive and continuous virus surveillance is yet to be established. We conducted DENV serotype and genotype surveillance in Bali to monitor viral transmission dynamics.MethodsWe enrolled febrile patients with dengue clinical symptoms in hospitals in Denpasar, Bali. Clinical evaluations and laboratory assessments were conducted, and blood samples were collected. DENV serotypes were determined using RT‐PCR, and genotyping was performed by sequencing the envelope protein gene and the complete genomes. Subsequently, phylogenetic analyses were conducted to analyse the recent data alongside retrospective sequence data.ResultsA total of 62 and 66 dengue patients were recruited during 2018–2020 and 2022, and from these, we obtained DENV serotype data for 49 and 48 individuals, respectively. Among the DENV analysed, the most prevalent serotype in 2018–2020 was DENV‐1 (30%) and shifted to DENV‐3 (57.6%) in 2022. When compared to data from the last 10 years, serotype shifting was clearly observed. We sequenced the genomes of 60 isolates and observed the presence of multiple virus lineages and the replacement of Genotype IV of DENV‐1 with Genotype I. The Cosmopolitan, Genotype I and Genotype II remained the predominant genotypes for DENV‐2, DENV‐3 and DENV‐4, respectively.ConclusionWe reveal that DENV serotype predominance in Bali has been shifting in the past 10 years. While genotype replacement occurred, continuous circulation of local endemic viruses was responsible for the annual outbreak of dengue. These findings indicate the genetic diversity and dynamic nature of DENV circulating in Bali. Routine virus surveillance is important to understand the cyclical patterns of DENV serotypes that is useful to predict the future outbreaks.
Exploring Subjective Theories of Assessment Among Preservice Physical Education Teachers in a Master’s Program
Authors: Liu Xiaolu , Liu Jingwen , Gurvitch Rachel , Wang Baofu 
Published: February 2025

Purpose: This study aimed to explore the subjective theories of assessment held by preservice physical education teachers in a master’s program, focusing on each assessment literacy component. Method: Using a descriptive phenomenological approach, 11 master’s program preservice physical education teachers (three females, eight males) were purposefully and conveniently recruited in the study. Data sources were interviews, an online survey, instructor’s notes, and assessment samples. Deductive and inductive thematic analysis in NVivo 12 was employed, ensuring trustworthiness through data triangulation, peer debriefing, and member checking. Results: Four themes were generated across multiple data courses. The themes are (a) understanding of assessment purposes, (b) challenges in assessment implementation, (c) self-referenced assessment interpretation, and (d) critical perspectives on assessment data. Conclusion: The findings highlight the need for a comprehensive assessment education program that addresses all aspects of preservice physical education teachers’ subjective theories of assessment, enhancing their assessment literacy while considering their diverse backgrounds and stages of training.
Exploring B-meson properties using relativistic independent quarks
Authors: Behera S. , Panda S. 
Published: February 2025

In this paper, we examine the radially excited states of B-mesons: [Formula: see text] and [Formula: see text]-mesons. Our investigation uses the relativistic independent quark model, which relies on a flavor-independent average potential expressed in the scalar and vector square root form. We make phenomenological fit the potential model parameters, [Formula: see text] [Formula: see text]GeV, [Formula: see text] [Formula: see text]GeV for calculation of 1S state of B-mesons: [Formula: see text] (5.329[Formula: see text]GeV), [Formula: see text] [Formula: see text], which aligns well with theoretical and experimental data. For higher radially excited states (2S, 3S, 4S, 5S), we adjust [Formula: see text] [Formula: see text]GeV while keeping “a” fixed, yielding results consistent with other theoretical models. With these parameters, we compute the pseudoscalar and vector meson decay constants, magnetic transition rates, non-leptonic decay widths, branching fractions, rare decay widths, and semileptonic decay widths and branching fractions of the B-mesons. Our findings show reasonable agreement with lattice QCD calculations, experimental results and other theoretical predictions. For instance, our predicted radiative decay width for [Formula: see text] (1S) [Formula: see text] [Formula: see text](1S)[Formula: see text], sensitive to the [Formula: see text] and [Formula: see text], mass difference, can aid in experimentally determining the [Formula: see text], mass. Predicted non-leptonic branching fractions, such as [Formula: see text] [Formula: see text] and [Formula: see text], align with PDG values of [Formula: see text] and [Formula: see text]. Additionally, we calculate the dileptonic decays of [Formula: see text] and [Formula: see text], which agrees with CMS, LHCb and PDG results. Our semileptonic decays of [Formula: see text] and [Formula: see text] mesons are computed and compared with PDG results. Furthermore, the results obtained for mass difference, [Formula: see text] and [Formula: see text], mixing parameters, [Formula: see text] and [Formula: see text], [Formula: see text] (0.1866 and 0.4993) of [Formula: see text] and [Formula: see text] oscillations, shows good agreement with PDG data, validating our model.
Health-related quality of life in patients with HR+/HER2− early breast cancer treated with ribociclib plus a nonsteroidal aromatase inhibitor: results from the NATALEE trial
Authors: Fasching Peter A. , Slamon Dennis , Nowecki Zbigniew , Kukielka-Budny Bozena , Stroyakovskiy Daniil , Yardley Denise A. , Huang Chiun-Sheng , Chan Arlene , Chia Stephen , Martín Miguel , Rugo Hope S. , Loi Sherene , Hurvitz Sara , Untch Michael , Afenjar Karen , Fresco Rodrigo , Danyliv Andriy , Ferrusi Ilia , Li Zheng , Hortobagyi Gabriel 
Published: February 2025

Abstract
Purpose: The phase 3 NATALEE trial reported a statistically significant invasive disease-free survival benefit with ribociclib plus nonsteroidal aromatase inhibitor (NSAI) versus an NSAI alone in stage II/III hormone receptor–positive, human epidermal growth factor receptor 2–negative (HR+/HER2−) early breast cancer (EBC). Here we report health-related quality of life (HRQOL) data from NATALEE. Patients and methods: Patients were randomized to receive ribociclib plus NSAI or NSAI alone. Patient-reported outcome scores (EORTC QLQ-C30 global health status and physical, social, and emotional functioning domains; EORTC QLQ-BR23 breast-symptoms scale; health on a visual analog scale of EQ-5D-5L; and the Hospital Anxiety and Depression Scale) were assessed. The prespecified primary HRQOL endpoint was physical functioning. Mean scores and time-categorical and prespecified linear-time repeated-measure models were used to evaluate HRQOL changes during treatment. Results: HRQOL was evaluated in all patients in the ribociclib plus NSAI (n = 2549) and NSAI alone (n = 2552) arms. Compliance was high in both arms (≈93%-97%). Mean scores did not differ meaningfully from baseline for any analyzed domain. Likewise, neither a meaningful change from baseline (in either treatment arm) nor a difference between arms was observed during treatment in the time-categorical, model-adjusted mean scores for any HRQOL domains—using published thresholds for interpreting longitudinal and between-group differences, with all values being within 0.5 SD of their baseline values. Linear-time regression analysis confirmed these findings. Conclusions: These analyses of NATALEE show that adding adjuvant ribociclib to an NSAI does not negatively impact HRQOL in patients with HR+/HER2− EBC.
Germline-Somatic Interactions in BRCA-Associated Cancers: Unique Molecular Profiles and Clinical Outcomes Linking ATM to TP53 Synthetic Essentiality
Authors: Arafa Ali T. , Yadav Siddhartha , Marshall Catherine H. , Mauer Elizabeth , Huang Minxuan , Yilma Binyam , van der Pol Ymke , Fragkogianni Stamatina , Teslow Emily A. , Kellen Samuel , Boytim Ella , Luo Christine , Ludwig Megan , Zhang Weijie , Jayaraj Arockia , Armstrong Deborah K. , Isaacs William B. , Drake Justin M. , Nguyen Hai Dang , Huang R. Stephanie , Chao Calvin Y. , Lou Emil , Dehm Scott M. , Couch Fergus J. , Hwang Justin H. , Antonarakis Emmanuel S. 
Published: February 2025

Abstract
Background: Germline alterations in homologous recombination repair (gHRR) genes impact the pathogenesis, treatment options, and survival of cancer patients. However, distinct gHRR gene alterations may differentially impact treatment response and oncogenic signaling. Here we interrogated genomic and transcriptomic data and assessed clinical outcomes of patients with gHRR mutations across four BRCA-associated cancers (breast, ovarian, pancreatic, and prostate cancers) to identify therapeutic vulnerabilities. Methods: We assessed 24,309 patients undergoing matched tumor/normal next-generation DNA and RNA sequencing. Annotated gHRR gene variants (gBRCA1, gBRCA2, gPALB2, gATM, gCHEK2) were analyzed. Hazard ratios were used to assess survival outcomes comparing germline versus sporadic groups. Somatic alterations and their frequencies were compared across gHRR-altered groups. Differential gene expression and gene set enrichment analysis was used to compare transcriptomic profiles. Results: Somatic TP53 mutations were depleted in gATM carriers (p&lt;0.05) across all four BRCA-associated cancers by up to 2.5-fold. Tumors with gBRCA1/2 mutations were associated with improved survival in ovarian cancer patients, and had consistent enrichment of TP53 mutations in all four cancers. gATM mutations displayed elevated p53 transcriptional activity in all four cancers, with significance reached in breast and prostate cancers (p&lt;0.01). In breast, ovarian, and prostate cancers, gATM tumors demonstrated significantly increased inflammatory pathways (p&lt;0.001). Finally, using gene-dependency data, we found that cell lines that were highly dependent on ATM were co-dependent on canonical p53 function. Conclusion: gATM-associated cancers appear to require intact p53 activity and this synthetic essentiality may be used to guide targeted therapies that perturb canonical TP53 function.