bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi‐informant assessment of treatment integrity in the classroom
Authors: Dart Evan H. , Collier‐Meek Melissa A. , Chambers Caitlyn , Murphy Ashley 
Published: February 2020

AbstractAssessing the degree to which interventions are implemented in school settings is critical to making decisions about student outcomes. School psychologists may not be available to regularly conduct observations of intervention implementation, however, their data may be used alongside other methods for multi‐informant assessment. Teacher self‐report is a commonly used and feasible assessment method. Students have been trained to implement interventions with their peers in instances where traditional adult interventionists were unavailable. This exploratory study investigated the accuracy with which classroom teachers and middle and high school students assessed implementation of the Good Behavior Game and the impact of performance feedback on their accuracy. Results indicated that most students and teachers were able to provide accurate assessments of treatment integrity compared to researcher direct observation; however, some required performance feedback to do so. These findings suggest that multi‐informant assessment may be a feasible and accurate way for school psychologists to collect formative treatment‐integrity data in the classroom. Limitations and future directions are discussed.
Working toward equitable gifted programming: The school psychologist's role
Authors: Ottwein Jessica K. 
Published: February 2020

AbstractAs culturally, linguistically, and economically diverse students continue to be underrepresented in gifted programs, the beliefs that frame teacher perceptions of giftedness remain an important area of focus. Literature indicates that a lack of gifted‐specific coursework in teacher preparation programs may sustain ill‐formed preconceptions regarding giftedness, leading new teachers to rely on bias and stereotypic thinking when nominating students for gifted identification. Furthermore, deficit thinking and colorblind racial attitudes may interfere with the implementation of culture‐fair identification practices and the implementation of multicultural pedagogy meant to elicit unique strengths and engage culturally diverse students. This article explores these barriers to equitable programming and concludes with broad recommendations for school psychologists in advocating for traditionally underrepresented gifted students.
Influence of Type D personality on quality of life in university students: The mediating effect of health‐promoting behavior and subjective health status
Authors: Kim Sung Reul , Nho Ju‐Hee , Kim Hye Young 
Published: February 2020

AbstractThis study aimed to test a hypothetical path model estimating the influence of Type D personality on health‐promoting behaviors (HPB), subjective health status, and quality of life (QoL) in university students, and to verify the mediating effects of HPB and subjective health status between Type D personality and QoL. A structural equation model involving 380 university students was used. Data were collected between November and December 2018 via structured questionnaires and analyzed using SPSS 25.0 and Amos 23.0. The model's fit indices were adequate. Type D personality had a direct effect on QoL and an indirect effect on QoL via HPB and subjective health status. Type D personality, HPB, and subjective health status explained 67.6% of the total variance in QoL. Intervention programs that consider Type D personality, HPB, and subjective health status may be useful to improve university students' QoL.
Pulmonary hypertension in children with Down syndrome
Authors: Bush Douglas , Galambos Csaba , Dunbar Ivy David 
Published: February 2020

AbstractIndividuals with Down syndrome (DS) have an increased risk of developing pulmonary hypertension (PH). In this review, we explore the epidemiology and clinical characteristics of PH in the population with DS and examine genetic, molecular and clinical contributions to the condition. The presence of an additional copy of chromosome 21 (trisomy 21) increases the risk of developing PH in children with DS through many mechanisms, including increased hemodynamic stress in those with congenital heart disease, hypoxemia through impaired ventilation to perfusion matching secondary to developmental lung abnormalities, pulmonary hypoplasia from pulmonary vascular endothelial dysfunction, and an increase in pulmonary vascular resistance often related to pulmonary comorbidities. We review recent studies looking at novel biomarkers that may help diagnose, predict or monitor PH in the population with DS and examine current cardiopulmonary guidelines for monitoring children with DS. Finally, we review therapeutic interventions specific to PH in individuals with DS. Contemporary work has identified exciting mechanistic pathways including the upregulation of antiangiogenic factors and interferon activity, which may lead to additional biomarkers or therapeutic opportunities. Throughout the manuscript, we identify gaps in our knowledge of the condition as it relates to the population with DS and offer suggestions for future clinical, translational, and basic science research.
Longitudinal muscular column in the prostatic urethral wall: Its form, shape, and possible function based on mathematical simulation in ejaculation
Authors: Hur Mi‐Sun , Lee Hye Won , Yang Hun‐Mu , Kwon Hyun‐Jin , O Jehoon , Lee Seunggyu , Oh Chang‐Seok 
Published: February 2020

AbstractBackgroundThe shape and function of the longitudinal muscular column (LMC) of the prostate have not been established in detail. The present study was undertaken to elucidate the roles of the LMC of the posterior wall of the prostatic urethra (PSU) in the emission phase of ejaculation by investigating the form and muscular arrangement of the LMC.MethodsProstates and urinary bladders were obtained from 14 Korean adult cadavers. Nine specimens were histologically analyzed using hematoxylin and eosin, Masson's trichrome, and Verhoeff‐van Gieson staining. Two specimens were scanned using microcomputed tomography (micro‐CT), and all scanned images were reconstructed into a three‐dimensional model.ResultsAt the proximal level of the prostate, the ejaculatory ducts (EDs) and prostatic utricle (PU) together were surrounded by circular smooth‐muscle fibers. However, at the seminal colliculus (SC) where the EDs and PU opened, they were mainly surrounded by an abundance of longitudinal fibers. The longitudinal fibers posterior to the EDs and PU formed a distinctive LMC in the posterior urethral wall. In histologic sections and micro‐CT images, the LMC extended distally from the level of the SC to the level of the membranous urethra (MBU). We simulated a potential mechanism of LMC using a mathematical model of its movements.ConclusionsComprehensive analyses based on in‐depth assessment of histologic characteristics and micro‐CT images demonstrated extension of the LMC from the level of the SC to the level of the MBU, enabling a better understanding of ejaculation physiology involving the LMC. These results suggest that the LMC in the posterior wall of the PSU is a critical component of ejaculation by facilitating the ejection of seminal vesicle fluid into the PSU via well‐coordinated contractions.
Defect pattern recognition on wafers using convolutional neural networks
Authors: Wang Rui , Chen Nan 
Published: February 2020

AbstractIn semiconductor manufacturing, wafer testing is performed to ensure the performance of each product after wafer fabrication. The wafer map is used to visualize the color‐coded wafer test results based on the locations. The defects on the wafer map may be randomly distributed or form clustered patterns. The various clustered defect patterns are usually caused by assignable faults. The identification of the patterns is thus important to provide valuable hints for the root causes diagnosis. Solving the problems helps improve the manufacturing processes and reduce costs. In this study, we present a novel convolutional neural network (CNN)–based method to automatically recognize the defect pattern on wafer maps. Our method uses polar mapping before the training of CNN to transform the circular wafer map into a matrix, which can be processed within CNN architecture. This procedure also reduces the input size and solves variations in wafer sizes and die sizes. To eliminate the effects of rotation, we apply data augmentation in the training of CNN. Experiments using the real‐world dataset prove the effectiveness and superiority of our method.
Application of 6‐aminoquinolyl‐N‐hydroxysuccinimidyl carbamate derivatization for enhanced peptide mapping analysis of non‐biological complex drug glatiramer acetate using liquid chromatography/electrospray ionization collision‐induced dissociation high‐resolution mass spectrometry
Authors: Mesonzhnik Natalia V. , Kuznetsov Roman M. , Bochkareva Natalia L. , Appolonova Svetlana A. 
Published: February 2020

RationaleGlatiramer acetate (GA) (Copaxone®) is a non‐biological complex drug (NBCD) comprising random‐sequence polymer chains of four amino acids (MW ~ 5–9 kDa) with unknown structure. The characterization of NBCDs by reversed‐phase liquid chromatography/mass spectrometry (RPLC/MS) peptide mapping is often impeded by insufficient separation and/or low sensitivity. To overcome this issue, pre‐column derivatization of GA peptide digest was used to improve RPLC/MS detectability and to generate a comprehensive peptide profile.MethodsAmino groups of peptides generated by trypsin digestion of GA were derivatized using 6‐aminoquinolyl‐N‐hydroxysuccinimidyl carbamate (AQC) reagent. The derivatized mixture of random‐sequence peptides was analyzed by liquid chromatography/positive‐mode electrospray ionization collision‐induced dissociation high‐resolution mass spectrometry (RPLC/ESI‐CID‐HRMS/MS). Data‐independent LC/MSE mode was used for data acquisition.ResultsThe derivatization of the GA peptide mixture increased the detectability of RPLC/ESI‐CID‐HRMS/MS analysis. The efficacy of the procedure was demonstrated by using selected peptides related to different polymeric chain origins. The resultant peptides were derivatized in a predictable manner giving a minimum of side products. The reproducibility of the developed method was demonstrated by comparing peptide elution profiles derived from six Copaxone® lots.ConclusionsApplication of the AQC pre‐column derivatization provides a framework that could be used as an attractive approach for monitoring the quality and characterization of NBCD products in the pharmaceutical industry.
Initial clinical experience of single‐incision robotic colorectal surgery with da Vinci SP platform
Authors: Noh Gyoung Tae , Oh Bo‐Young , Han Myunghyun , Chung Soon Sup , Lee Ryung‐Ah , Kim Kwang Ho 
Published: February 2020

AbstractBackgroundThe da Vinci Surgical System (Intuitive Surgical, Sunnyvale, CA) was introduced to overcome the limitations of single‐incision laparoscopic surgery, which is challenging due to its restrictions regarding triangulation and retraction. The purpose of this article is to describe the initial experience with single‐incision surgery using the da Vinvci Single‐Port Platform (dVSP).MethodsThe medical records of patients with colorectal disease, who underwent single‐incision robotic surgery using the dVSP, were retrospectively reviewed.ResultsFive patients with appendiceal and colorectal cancer, and two with diverticulitis were enrolled. All procedures were completed using a pure single‐incision approach, with an exception for low anterior resection. There were two minor complications. For patients with colorectal cancer, the number of retrieved lymph nodes and status of the resection margin were acceptable, and cosmetic results were satisfactory.ConclusionThe dVSP is a novel surgical platform that can be used as an alternative surgical modality for colorectal surgery.
Fixed‐time attitude tracking control for spacecraft based on adding power integrator technique
Authors: Jiang Boyan , Li Chuanjiang , Hou Shixi , Ma Guangfu 
Published: February 2020

SummaryIn this article, the fixed‐time attitude tracking problem for rigid spacecraft is investigated based on the adding‐a‐power‐integrator control technique. First, a fixed‐time attitude tracking controller is designed to guarantee fixed‐time convergence of tracking errors. Then, by considering the presence of random disturbance and actuator faults, an adaptive fault‐tolerant attitude tracking controller is designed to guarantee tracking errors converge to a residual set of zero in a fixed time. The complete bounds on settling time are derived independently of initial conditions. The simulation results illustrate the highly precise and robust attitude control performance obtained by using the proposed controllers.
Missed opportunities for observation‐based ecology in the Next Generation Science Standards
Authors: Merritt Eileen G. , Bowers Nicole 
Published: February 2020

AbstractObservation‐based ecology (OBE) generates critical knowledge about the health of ecological systems and human impacts on these systems. Systematic observations of organisms and processes from an early age can help children develop ecological knowledge and skills, and deepen their connection to the natural world. Yet recent educational reforms may privilege other scientific and engineering practices (SEPs) over OBE methods. We used lexical analysis of Next Generation Science Standards documents to identify instances of observational methods suggested in the SEPs and ecology‐related performance expectations (PEs). We identify where observations are included and omitted in these documents. Only 16 of the 175 (9%) learning progression descriptions for the SEPs explicitly mention observations. Nine out of 142 (6%) PEs related to ecology require observations. OBE opportunities were particularly scarce in middle and high school years, and missing entirely from PEs for disciplinary core ideas related to ecosystems and human impacts on ecosystems. We consider how these missed opportunities may constrain place‐based learning in natural environments, and reflect on implications for educators, students, and nonhuman others.
Green Synthesis of Fluorescent Carbon Dots from Cherry Tomatoes for Highly Effective Detection of Trifluralin Herbicide in Soil Samples
Authors: Lai Zhan , Guo Xinyuan , Cheng Zhenfang , Ruan Guihua , Du Fuyou 
Published: February 2020

AbstractA simple, economical and green synthesis method for the preparation of water‐soluble carbon quantum dots (CQDs) has been developed via hydrothermal treatment of fresh cherry tomatoes without any other reagents. The as‐prepared CQDs exhibited excellent excitation‐wavelength‐dependent photoluminescence property and high selective response to trifluralin over other selected herbicide in soil samples, thus, a CQDs‐based sensing platform for trifluralin determination was established by evaluating the change of the fluorescence intensity of CQDs with trifluralin. Under the optimized conditions, the sensing system displayed a linear relationship with the trifluralin concentrations in the range of 0.050‐200 μM, and the limit of detection (LOD) was 0.5 nM. Satisfactory repeatability, reproducibility, recovery results (94.6‐103.2%) are achieved for the determination of trifluralin in real soil samples. Real sample study in soil samples revealed that the proposed sensing system was promising for applications in environmental monitoring.
CuBr2@g‐C3N4‐Catalyzed Highly Selective Aerobic Oxidation of Alcohol and Toluene Derivatives
Authors: Rani Verma Padma , Payra Soumen , Khan Fahmida , Penta Santosh , Banerjee Subhash 
Published: February 2020

AbstractPolymeric graphitic carbon nitride (g‐C3N4) supported CuBr2 hybrid material (CuBr2@g‐C3N4) was developed by impregnation of CuBr2 on g‐C3N4 sheets. The morphology and physiochemical properties were analyzed by powder XRD, SEM, and HRTEM studies. The hybrid CuBr2@g‐C3N4 material showed excellent selectivity in the aerobic oxidation of primary/secondary alcohols and benzoins to the corresponding carbonyl compounds in absence of any oxidizing agents. Further, CuBr2@g‐C3N4 demonstrated direct oxidation of toluene derivatives to corresponding aldehydes in excellent yields. The g‐C3N4 support provides excellent stability and heterogeneity to CuBr2 and was recovered simply by filtration and reused for ten times without appreciable loss in catalytic activity.
Reusable, Free‐Standing MoS2/rGO/Cu2O Ternary Composite Films for Fast and Highly Efficient Sunlight Driven Photocatalytic Degradation
Authors: Gopalakrishnan Arthi , Pratap Singh Satyam , Badhulika Sushmee 
Published: February 2020

AbstractIn this work, a novel free‐standing three‐dimensional MoS2/rGO/Cu2O ternary composite grown on etched carbon paper is successfully synthesized by simple hydrothermal method and demonstrated for very fast photocatalytic degradation of methylene blue (MB), rhodamine B (RhB) and binary mixture MB‐RhB under natural sunlight irradiation. Interestingly, the ternary film exhibits fast dyes degradation of ∼98 % within 45 min of irradiation indicating its excellent photocatalytic activity owing to efficient absorption in broad range of spectrum and the combined synergistic effects of the nanostructures. In addition, the stable photocatalyst film is reused six times without any major loss in efficiency thus making it suitable for real time applications for sustainable environment. The as‐prepared free‐standing, reusable and stable film demonstrates a wide potential in environmental monitoring applications such as removal of organic pollutants and wastewater treatment.
FA‐Assistant Iodide Coordination in Organic–Inorganic Wide‐Bandgap Perovskite with Mixed Halides
Authors: Xie Yue‐Min , Zeng Zixin , Xu Xiuwen , Ma Chunqing , Ma Yuhui , Li Menglin , Lee Chun‐Sing , Tsang Sai‐Wing 
Published: February 2020

AbstractMixed‐halide wide‐bandgap perovskites are key components for the development of high‐efficiency tandem structured devices. However, mixed‐halide perovskites usually suffer from phase‐impurity and high defect density issues, where the causes are still unclear. By using in situ photoluminescence (PL) spectroscopy, it is found that in methylammonium (MA+)‐based mixed‐halide perovskites, MAPb(I0.6Br0.4)3, the halide composition of the spin‐coated perovskite films is preferentially dominated by the bromide ions (Br−). Additional thermal energy is required to initiate the insertion of iodide ions (I−) to achieve the stoichiometric balance. Notably, by incorporating a small amount of formamidinium ions (FA+) in the precursor solution, it can effectively facilitate the I− coordination in the perovskite framework during the spin‐coating and improve the composition homogeneity of the initial small particles. The aggregation of these homogenous small particles is found to be essential to achieve uniform and high‐crystallinity perovskite film with high Br− content. As a result, high‐quality MA0.9FA0.1Pb(I0.6Br0.4)3 perovskite film with a bandgap (Eg) of 1.81 eV is achieved, along with an encouraging power‐conversion‐efficiency of 17.1% and open‐circuit voltage (Voc) of 1.21 V. This work also demonstrates the in situ PL can provide a direct observation of the dynamic of ion coordination during the perovskite crystallization.
Tumor mutational load, CD8+ T cells, expression of PD-L1 and HLA class I to guide immunotherapy decisions in NSCLC patients
Authors: Hurkmans Daan P. , Kuipers Merian E. , Smit Jasper , van Marion Ronald , Mathijssen Ron H. J. , Postmus Piet E. , Hiemstra Pieter S. , Aerts Joachim G. J. V. , von der Thüsen Jan H. , van der Burg Sjoerd H. 
Published: February 2020

Abstract
Objectives
A minority of NSCLC patients benefit from anti-PD1 immune checkpoint inhibitors. A rational combination of biomarkers is needed. The objective was to determine the predictive value of tumor mutational load (TML), CD8+ T cell infiltration, HLA class-I and PD-L1 expression in the tumor.

Materials and methods
Metastatic NSCLC patients were prospectively included in an immune-monitoring trial (NTR7015) between April 2016-August 2017, retrospectively analyzed in FFPE tissue for TML (NGS: 409 cancer-related-genes) and by IHC staining to score PD-L1, CD8+ T cell infiltration, HLA class-I. PFS (RECISTv1.1) and OS were analyzed by Kaplan–Meier methodology.

Results
30 patients with adenocarcinoma (67%) or squamous cell carcinoma (33%) were included. High TML was associated with better PFS (p = 0.004) and OS (p = 0.025). Interaction analyses revealed that patients with both high TML and high total CD8+ T cell infiltrate (p = 0.023) or no loss of HLA class-I (p = 0.026), patients with high total CD8+ T cell infiltrate and no loss of HLA class-I (p = 0.041) or patients with both high PD-L1 and high TML (p = 0.003) or no loss of HLA class-I (p = 0.032) were significantly associated with better PFS. Unsupervised cluster analysis based on these markers revealed three sub-clusters, of which cluster-1A was overrepresented by patients with progressive disease (15 out of 16), with significant effect on PFS (p = 0.007).

Conclusion
This proof-of-concept study suggests that a combination of PD-L1 expression, TML, CD8+ T cell infiltration and HLA class-I functions as a better predictive biomarker for response to anti-PD-1 immunotherapy. Consequently, refinement of this set of biomarkers and validation in a larger set of patients is warranted.
Thesen zu Zukunft und Verfahrensvielfalt in psychotherapeutischer Forschung, Aus- und Weiterbildung
Authors: Strauß Bernhard 
Published: February 2020

ZusammenfassungDie vom Gesetzgeber im vergangenen Jahr verabschiedete Reform der Psychotherapieausbildung hat zur Folge, dass die bestehenden Psychologie-Bachelor- und Psychologie-Master-Studiengänge an die neuen Regelungen angepasst werden müssen. Dadurch werden auch neue Rahmenbedingungen für die Weiterentwicklung der Psychotherapie geschaffen. Bei der Frage, wie die Psychotherapie der Zukunft aussehen soll, wird kaum ein Thema so kontrovers diskutiert wie die Rolle der Verfahrensvielfalt in Forschung, Aus- und Weiterbildung. Die Deutsche Gesellschaft für Psychologie und der Fakultätentag Psychologie haben aus diesem Anlass Vertreterinnen und Vertreter unterschiedlicher Psychotherapierichtungen und Interessensgruppen zu einem konstruktiven Dialog eingeladen. Als Ergebnis dieses Symposiums wurden die sog. Osnabrücker Thesen zur Zukunft der Psychotherapie formuliert. Zusätzlich wurden erste Ideen zusammengetragen, wie sich Aspekte der Verfahrensvielfalt strukturell weiterentwickeln lassen.