bluuebunny/crossref_metadata_2025_split huggingface dataset:
Die Burg Bibliothek - ein Ort der Inspiration
Authors: Runge Petra 
Published: December 2019

Abstract
Die Burg Bibliothek ist das mediale Zentrum der Burg Giebichenstein Kunsthochschule Halle. Das Zusammenwirken freier und angewandter Disziplinen sowie die künstlerischen und gestalterischen Bereiche sind für das Profil der Kunsthochschule bestimmend und damit auch für das Profil der Burg Bibliothek. Heute ist die Einrichtung die wichtigste und umfassendste wissenschaftliche Spezialbibliothek zu Kunst und Design des 20./21. Jahrhunderts im mitteldeutschen Raum. Sie umfasst zudem eine Materialsammlung, auch sind das Hochschularchiv sowie die Kustodie der Bibliothek zugeordnet. Der 2015 entstandene Architekturneubau ist inzwischen mehrfach preisgekrönt.
Unification of data from various seismic catalogues to study seismic activity in the Carpathians Mountain arc
Authors: Braclawska Agnieszka , Idziak Adam Filip 
Published: December 2019

AbstractThe Carpathian Mountainsarc is the most seismically active area in Central Europe. Analysis of the seismicity of entire Carpathian arc requires data from each of the particular catalogues which have to be properly and uniformly entered, standardized and merged. For our study we first had to prepare a database of seismic events (ML≥ 1.6) compiled from the data of earthquakes taken from individual national seismic networks as well as data from international seismic centers. However, a careful review of these catalogues has uncovered significant inconsistencies, particularly discrepancies in the description of the location, magnitude and completeness of seismic events. To address these inconsistencies, a newly created compound earthquake catalogue was compiled from the aforementioned seismic catalogues and included events that occurred in the Carpathian Mountains arc area between 1976 and 2017. This work is intended to point out some of the problems associated with collecting data from various seismic catalogues as well as the need for their very careful verification, in order to create a uniform set of seismic data across a large area spanning numerous countries. The results suggest that compiling a uniform and dependable earthquake catalogue is crucial for reliable seismic studies.
Arritmia ventricular casi fatal asociada a uso de psicofármacos
Authors: Amado-Tineo José , Tazza-Quiroz Fernando , Vargas-Alayo Marvin 
Published: December 2019

El uso de psicofármacos es cada vez más frecuente por problemas emergentes como la depresión. Se presenta el caso de una mujer de 47 años que recibía tratamiento antidepresivo (fluoxetina y levomepromazina) y fue llevada a emergencia por presentar en su domicilio trastorno de conciencia súbito, evidenciándose durante su estancia hospitalaria dos episodios de taquicardia ventricular sin pulso que respondieron satisfactoriamente a desfibrilación y reanimación cardiopulmonar avanzada. Se comenta la prolongación del intervalo QT asociada a uso de antidepresivos y antipsicóticos, así como sus factores de riesgo. Finalmente se destaca la importancia de tener presente la relación entre psicofármacos y arritmias ventriculares potencialmente fatales, siendo necesario realizar un electrocardiograma a estos pacientes que consulten al servicio de emergencia.
Desarrollo mecánico y experimental de un implante discal cervical flexible
Authors: Alvarez Carlos , Lean Paul , Rodríguez Rodolfo , Pacussich Claudio , Noriega Ainsworth , Navarro Erick 
Published: December 2019

Introducción: La artroplastía cervical es una cirugía que implica el uso de implantes discales con la capacidad de conservar el movimiento del segmento. Constituye un reto para paises como el nuestro desarrollar alternativas a los altos costos de los mencionados implantes, con diseños patentado, elaborado viables de manufacturar, con biocompatibilidad, seguridad, y que simule lo máximo posible los movimientos cervicales fisiológicos. Objetivo: Desarrollar la geometría y mecánica de un diseño discal patentado, elaborado, sea por manufactura aditiva de titanio ELI, así como verificar su compatibilidad con la fisiología de los movimientos cervicales. Métodos: El diseño del estudio tuvo tres etapas iterativas: la primera, el desarrollo de la geometría del implante y el estudio de elementos finitos utilizando como referencia normas internacionales; en segundo lugar, se desarrollaron estudios de metalografía, caracterización del material incluyendo pruebas de fatiga del implante; finalmente, se utilizó un modelo animal cadavérico para confirmar la compatibilidad del implante con los movimientos cervicales. Resultados: Se demostró que el implante elaborado sea por manufactura aditiva o por forja, fue compatible con las normas internacionales. Se realizaron 84 estudios de rayos X en 18 cuellos de porcino. En el 100% de las columnas cervicales de los porcinos, el rango en flexión fue menor que el de extensión. Existió mayor rango de movimiento cuando se utilizaron dos implantes y cuando el implante fue más grande. Conclusiones: El implante cervical flexible elaborado por forja o por manufactura aditiva de titanio ELI presentó resultados prometedores, por lo que podría postularse su uso experimental en pacientes tributarios de artroplastía cervical.
Asociación entre los factores sociodemográficos, obstétricos y patológicos con la muerte fetal tardía: estudio de casos y controles en un hospital de Perú
Authors: Martínez-López Andrés Modesto , Vargas-Herrera Javier Roger Raúl , Mini-Díaz Elsy Haydee 
Published: December 2019

Introducción: En el Perú, poco se conoce acerca de los factores de riesgo asociados a la muerte fetal tardía, lo que se considera información valiosa para implementar estrategias de prevención. Objetivos: Evaluar la asociación entre factores sociodemográficos, obstétricos y patológicos y la muerte fetal tardía en un hospital peruano. Métodos: Estudio retrospectivo de casos y controles entre el mes de julio de 2014 y junio de 2016. Los casos fueron gestantes que tuvieron muerte fetal intrauterina, y los controles fueron gestantes que tuvieron un recién nacido vivo. Se evaluaron factores como nivel educativo, ocupación, número de controles prenatales (CPN), y la presencia de complicaciones como parto pre-termino, pre-eclampsia o retardo del crecimiento intrauterino (RCIU) Resultados: Se incluyeron 60 casos y 120 controles. El nivel educativo primario (OR: 4,3; IC 95% 1,0-18,0), la ocupación trabajadora (OR: 3,8; IC 95% 1,3-11,0), no tener CPN (OR: 21,0; IC 95% 2,6-170,1), la pre-eclampsia (OR: 4,1; IC 95% 1,3-12,7), el parto pretérmino (OR: 10,1; IC 95% 4.7-21,7) y RCIU (OR: 7,0; IC 95% 2,4-20,5) se asociaron con la mortalidad fetal. Conclusión: Existen factores de riesgo sociodemográficos, obstétricos y patológicos asociados a tener muerte fetal tardía.
A Comparative Study of Two Real Root Isolation Methods
Authors: Akritas A. G. , Strzebonski A. W. 
Published: December 2019

Recent progress in polynomial elimination has rendered the computation of the real roots of ill-conditioned polynomials of high degree (over 1000) with huge coefficients (several thousand digits) a critical operation in computer algebra.
To rise to the occasion, the only method-candidate that has been considered by various authors for modification and improvement has been the Collins-Akritas bisection method [1], which is a based on a variation of Vincent’s theorem [2].
The most recent example is the paper by Rouillier and Zimmermann [3], where the authors present “... a new algorithm, which is optimal in terms of memory usage and as fast as both Collins and Akritas’ algorithm and Krandick variant ...” [3]
In this paper we compare our own continued fractions method CF [4] (which is directly based on Vincent’s theorem) with the best bisection method REL described in [3]. Experimentation with the data presented in [3] showed that, with respect to time, our continued fractions method CF is by far superior to REL, whereas the two are about equal with respect to space.
Numerical Study of the Combined Free-Forced Convection and Mass Transfer Flow Past a Vertical Porous Plate in a Porous Medium with Heat Generation and Thermal Diffusion
Authors: Alam M. S. , Rahman M. M. , Samad M. A. 
Published: December 2019

The problem of combined free-forced convection and mass transfer flow over a vertical porous flat plate, in presence of heat generation and thermaldiffusion, is studied numerically. The non-linear partial differential equations and their boundary conditions, describing the problem under consideration, are transformed into a system of ordinary differential equations by using usual similarity transformations. This system is solved numerically by applying Nachtsheim-Swigert shooting iteration technique together with Runge-Kutta sixth order integration scheme. The effects of suction parameter, heat generation parameter and Soret number are examined on the flow field of a hydrogen-air mixture as a non-chemical reacting fluid pair. The analysis of the obtained results showed that the flow field is significantly influenced by these parameters.
Biosensor Response at Mixed Enzyme Kinetics and External Diffusion Limitation in Case of Substrate Inhibition
Authors: Kulys J. 
Published: December 2019

The action of a biosensor containing non Michaelis-Menten enzyme was modeled at mixed enzyme kinetics and external diffusion limitation in the case of substrate inhibition. The calculations show that at the electrode surface multi steady-state concentrations of substrate may be generated if diffusion module is much larger than 1 and the substrate bulk concentration is much bigger than Michaelis-Menten parameter. The multi steady-state concentration generates multi response of the biosensor. The production of the multi steadystate may cause the biosensor response oscillation.
Dos estructuras simbólicas del mito de la Quintrala: la bruja y la femme fatale
Authors: Shagulian Jasmin Belmar 
Published: December 2019

Catalina de los Ríos y Lisperguer, best known as Quintrala, is a historical figure of the Chilean Colonial period. Within Chilean culture, she became a myth that developed into a literary character variously portraited as a witch, a murderer, and a parricide. To this day, these remain the portraits that have been reproduced in the literary narrative about the character.
In this work I will analyse the symbolic structures of the witch and the femme fatale, which are essential and reiterative in the construction of the narrative discourse about this literary character. For this purpose, I have chosen the figurative structuralism that views a literary text as a sermo mythicus, that is to say, as a myth in which symbolic structures are a part of the mythical discourse advocated by this theory; this kind of discourse is likewise a fundamental and inherent component of the myth of Quintrala that has not been studied as such.
This work aims to examine these symbolic structures embedded in the myth of La Quintrala by analysing and comparing Gustavo Frías’ latest novels, Tres nombres para Catalina: Catrala (2001) and Tres nombres para Catalina: la doña de Campofrío (2003), the work of Magdalena Petit, La Quintrala (2009), that of Mercedes Valdivieso, Maldita yo entre las mujeres (1991), as well as the historical essay Los Lisperguer y la Quintrala by Benjamín Vicuña Mackenna ([1877] 1944) in order to establish the existence through time of a rewriting and a transfiguration of the symbolic structures in these literary works.
La Guerra civil española como tema en la novela gráfica actual
Authors: Izquierdo José María 
Published: December 2019

The Spanish civil war and its postwar period remain two of the most important historical references of present-day Spain. Along with themes of strictly political nature addressing that period of time and with the negative aspects of the transition to democracy, themes of memory and postmemory (Hirsch 1992 / Liikanen 2015) appear. Both are closely related to – although not only to – the silencing of the victims of the mentioned historical periods. By this, I am referring to the ones defeated and to the next of kin of the disappeared.

Despite the famous affair of the so-called “gentleman’s agreement”, the “amnesia”, the “forgetfulness” or the “silence” of the democratic transition, a variety of narrative works have emerged in recent history; literary works that in various manners have the Civil War and Franco’s posterior dictatorship as topics or common threads in their narrations[1].
The consolidation of a new literary subgenre of hybrid characteristics combining the mode of narration found in novels and the specificities of the comic strip is a novelty in the context of Spanish literature. Although already canonized in the 1970’s in the United States (Eisner, 1978), the subgenre emerged in Spain during the end of the 1990’s. With the turn of the century, a new vision of the Spanish cartoon arrived: it was no longer fundamentally limited to the sphere of children, of satire, or of short comic strips in newspapers. With an expanded format, it began addressing the adult public.
In the selection of graphic novels that I am presenting, there are various narrative strategies and aesthetics elaborated from accounts from the Civil War, and its prolongation in the Second World War, by authors who were not protagonists in the real-life events themselves and whom I include within the wide concept of postmemory. The prevailing ideas in all the texts are as follows: the necessary recuperation of the memory of the Civil War, the presentation of the present as a result of the past and the importance of knowing the points of view of the defeated in order to update the cultural identities of the territorial sphere of the Spanish state

[1] I have already presented one such work during the «Romanist XV» « Escribir de Oídas: Final literature of the memory of the Spanish Civil War and its postwar period” (2012).
Social and Psychological Factors of Political Participation according to Recent European Social Survey Data
Authors: Bozogáňová Miroslava , Výrost Jozef 
Published: December 2019

While people have an influence on current political decisions, and as ordinary citizens represent the basis for political participation, depicting such political engagement in an empirical/practical way creates a concerning amount of methodological questions. Data obtained via the European Social Survey Round 1–7 offers the opportunity to outline and broaden the picture in terms of the personal (demographic and psychological) features of individuals who participate in politics to a greater or lesser degree. Participants from the seven rounds of the European Social Survey (ESS) were divided into three groups: higher, medium, and lower political participation (α = 0.642). A Scale of Political Participation was created based on ‘yes’ answers. It was found that those individuals who were female or had a lower level of education participated less, while older people were more politically participative than younger people. The psychological profile of these groups differs in terms of preferred values: attitudes, satisfaction, trust in people, and institutions.
THE PROSPECTS FOR THE USE OF microRNA AS DIAGNOSTIC AND PROGNOSTIC MELANOMA BIOMARKERS
Authors: Chulkova S. V. , Ryabchikov D. A. , Dudina I. A. , Kazakov A. M. , Egorova A. V. , Titov K. S. , Khagazheeva M. N. , Gladilina I. A. , Galaeva Z. M. , Lepkova N. V. , Tupitsyn N. N. 
Published: December 2019

Despite recent advances in targeted and immune therapy, 5‑year overall survival in stages III–IV of melanoma is 50 and 10–20 %, respectively. Modern melanoma biomarkers, which are used in clinical practice, are not sufficiently effective for early diagnosis and prognosis assessment. In the last decade, circulating microRNAs (miRNAs) have come to be regarded as “ideal” melanoma biomarkers. This article presents the characteristics of miRNA biogenesis, as well as provides a critical review of circulating miRNAs as promising diagnostic and prognostic melanoma biomarkers.
EVALUATION OF THE ANTITUMOR EFFICACY OF SYNTHETIC NEOANTIGEN PEPTIDES FOR THE MELANOMA VACCINE MODEL
Authors: Baryshnikova M. A. , Rudakova A. A. , Sokolova Z. A. , Burova O. S. , Kosobokova E. N. , Kosorukov V. S. 
Published: December 2019

Introduction. Personalized vaccine therapy that stimulates immune system to recognize mutant tumor neoantigens is one of the promising approaches of cancer treatment.Objective. Evaluation of immunogenicity and antitumor efficacy of synthetic neoantigen peptides and poly(I:C) adjuvant against murine melanoma B16F10.Materials and methods. 43 synthetic mutant neoantigen peptides selected earlier according to the bioinformatics analysis of the results of melanoma B16F10 sequencing were investigated. The study was performed in mice C57Bl / 6J with subcutaneously transplanted melanoma B16F10 after double vaccination by peptide groups with or without adjuvant poly(I:C). Immunogenicity of peptides was evaluated by ELISPOT that detected the number of interferon-gamma producing cells. Antitumor activity was evaluated on the base of tumor growth inhibition and the increase of the survival rate.Results. The number of interferon-gamma producing cells increased after in vitro stimulation by the peptides of the model vaccine in the group of mice which had been vaccinated by these peptides with the adjuvant. The number of interferon-gamma producing cells in vitro did not change after addition of vaccine peptides or any other peptides in the groups of mice that had been vaccinated by the peptides without the adjuvant as compared to the control group. Double vaccination by the peptides with the adjuvant induced a potent antitumor effect in some cases, three of the eight groups of the peptides with the adjuvant induced significant inhibition of tumor growth and the increase of survival rate in mice.Conclusion. Thereby, it was shown that vaccination of mice by peptides in combination with adjuvant poly(I:C) stimulated the cell immunity response, however, the increase of the number of interferon-gamma producing cells is not an indicator of the antitumor efficacy of neoantigen peptides.
INCREASE IN NKT CELLS – A MARKER OF EARLY PROGRESSING AT ADJUVANTVACCINOTHERAPY OF PATIENTS WITH A METASTATIC MELANOMA OF SKIN
Authors: Borunova A. A. , Chkadua G. Z. , Zabotina T. N. , Kadagidze Z. G. , Korotkova O. V. , Chertkova A. I. , Tabakov D. V. , Zakharova E. N. , Shoua E. K. , Petenko N. N. , Demidov L. V. , Mikhailova I. N. 
Published: December 2019

Introduction. Natural killer T lymphocytes (NKT) take place between the innate and acquired immune response. The ability of these cells to activate the antitumor immune response and inhibit immunological activity makes them the target of research in cancer patients. The radicality of surgical treatment of patients with metastatic melanoma (stage III–IV) is relatively conventional. In this regard, the possibility of adjuvant effective therapy of melanoma is actively investigated worldwide.The aim of the study is investigation of the importance of increasing the number of NKT cells in the peripheral blood of patients with metastatic melanoma after radical surgical removal of the tumor. Patients were treated with adjuvant regimen antitumor autologous dendritic cell therapy in form of vaccination.Materials and methods. The study included 39 patients with stage III and IV metastatic melanoma with regional and / or distant metastases after radical surgery. From the peripheral blood monocytes of each patient, an autologous vaccine was created from mature dendritic cells loaded with tumor lysate. The therapy continued until objective progression. The study included patients who received from 5 to 120 injections. The follow-up period ranged from 5 to 168 months.Results. It was shown that 14 (36 %) of patients had the number of NKT cells exceeding the norm (0–10 %) and in the course of vaccine therapy they had the progression of the disease in the period up to 2 years. In patients with relapse-free course of the disease in vaccine therapy (n = 13), the number of NKT lymphocytes did not exceed the norm both before and during therapy. Significantly shorter time to progression was revealed in patients with high initial content of NKT lymphocytes compared with patients with normal indices of NKT cells (6.5 months) – 95 % confidence limit 2,4–10,7 % vs 96,2 months (95 % confidence limit 63.8–128.6 %). Conclusion. An increased number of NKT cells in patients with stage III–IV metastatic melanoma after radical surgical treatment is a marker of early progression.
EFFECT OF THE SYNTHESIS TEMPERATURE OF POLYCARBOXYLATE-BASED SUPERPLASTICIZER ON THE PERFORMANCE OF CONCRETE
Authors: CETINKAYA GÜRER Sevil 
Published: December 2019

Good
quality Polycarboxylate superplasticizers (PCEs) production is increasingly
important due to development of the construction industry in the world. In this study, modified PCEs were synthesized
via free-radical polymerization of Translated
Polyethylene Glycol (TPEG), Thioglycolic Acid (TGA) and Acrylic Acid (AA), in
the presence of initiator and chain transfer agent according to molecular
structure design principle in different initiatory temperatures (40 and 60 oC).
The effects of PCEs synthesized at different temperatures on the concrete such
as water cutting, workability and compressive strength of 7 and 28 days’ have
been examined. Fourier transform
infrared spectroscopy (FTIR) was used for structural characterization.
Determining content of mercury in vitamin and mineral dietary supplements
Authors: Brodziak-Dopierała Barbara , Fischer Agnieszka , Derkacz Patrycja , Stojko Jerzy 
Published: December 2019

WstępSuplementy diety to produkty coraz częściej wybierane jako łatwy sposób na uzupełnienie niedoborów witamin i minerałów w codziennej diecie. Są to środki spożywcze podlegające prawu żywnościowemu a nie farmaceutycznemu, co przekłada się na znacznie mniejsze wymagania niż w przypadku leków. Również prosta i niekosztowna procedura ich rejestracji sprawia, że każdego roku zwiększa się liczba dostępnych preparatów. Celem pracy było oznaczenie zawartości rtęci w witaminowo-mineralnych suplementach diety oraz analiza uzyskanych wyników.Materiał i metodyDo badania wybrano 22 suplementy diety dostępne na polskim rynku, zawierające w swoim składzie witaminy i minerały. W zebranych próbkach oznaczono zawartość rtęci przy użyciu spektrometru absorpcji atomowej AMA 254.WynikiZawartość rtęci mieściła się w zakresie 0,22–5,85 µg/kg. Najwięcej rtęci – 4,51 µg/kg – występowało w preparacie uzupełniającym poziom cynku i miedzi. Najmniejsza zawartość wynosiła 0,31 µg/kg w preparacie witaminowo-mineralnym. Uzyskane wyniki analizowano w poszczególnych grupach suplementów diety w zależności od składnika głównego i wskazań do stosowania oraz od postaci farmaceutycznej. Obliczono także dzienne pobranie rtęci przy maksymalnych zalecanych dawkach w ciągu dnia, miesiąca, 3 miesięcy oraz roku. Uzyskane oznaczenia porównano
z obowiązującym w krajach Unii Europejskiej maksymalnym dopuszczalnym poziomem zawartości rtęci w suplementach diety oraz tymczasowym tygodniowym pobraniem PTWI, ustalonym przez JECFA.WnioskiPrzeprowadzona analiza wykazała, że poziom zawartości rtęci w badanych suplementach diety witaminowo-mineralnych nie został przekroczony. Stosowanie tych preparatów w ilości zalecanej przez producenta nie stwarza ryzyka dla zdrowia.