bluuebunny/crossref_metadata_2025_split huggingface dataset:
Translating Laura E. Richards into Polish
Authors: Czernow  Anna Maria , Wieczorkiewicz  Aleksandra 
Published: December 2024

In the process of translating Laura E. Richards’s poems into Polish, we decided to use two approaches: translating “Eletelephony” collectively and “My Japanese Fan” independently. In translating “Eletelephony” into Polish, we explain why and how we decided to stay faithful to the governing principle behind the poem rather than to its original word-play of ‘elephant’ and ‘telephone,’ which was impossible to maintain in Polish. The challenges we encountered while translating “My Japanese Fan” were different and concerned grammatical gender and the use of pronouns. Offering two translations to “My Japanese Fan,” we explain our different translation strategies—with Aleksandra opting for playing with words and meaning, and Anna choosing to emphasize rhythm and rhyme.
Conceptual framework to provide culturally congruent care to epilepsy patients in selected rural communities in South Africa
Authors: Nemathaga Muofheni , Maputle Maria S. , Makhado Lufuno , Mashau Ntsieni S. 
Published: December 2024

Background: Epilepsy is a neurological disorder affecting millions of people in Africa. Among other reported findings, many people living with epilepsy (PLWE) believe that the condition is caused by spiritual factors. Previous studies have revealed that majority of PLWE are not receiving adequate care and treatment because of diverse cultural beliefs associated with epilepsy. Consequently, they consult either faith-based healers or traditional healers. Others, however, acknowledge the medical causes of epilepsy and seek developed medical treatment.Aim: To develop a culturally congruent care conceptual framework to provide comprehensive and holistic epilepsy care.Setting: This study was conducted in the selected rural communities of Limpopo and Mpumalanga provinces.Methods: A qualitative multi-method research approach was employed and sub-divided into three phases. Phase 1: All 15 articles were reviewed and appraised using the Critical Appraisal Skills Programme (CASP) rating tool. Phase 2 involved two stages of empirical study in which an exploratory-descriptive study design was used. The study population comprised of 20 traditional healers, 15 faith-based healers, 20 professional nurses and 22 PLWE. Data were collected using in-depth individual interviews and analysed through eight Tesch’s steps of data analysis. Following data analysis, Phase 3 entailed synthesising the systematic and empirical findings into a conceptual framework.Results: Three themes that emerged from the findings were cultural epilepsy interventions, faith-based epilepsy intervention and medically developed epilepsy interventions.Conclusion: Incorporation of cultural beliefs, values and practices into the medically developed management of epilepsy is crucial for providing culturally congruent care that is preferred by majority of PLWE.Contribution: Healthcare providers may tailor care interventions that are culturally appropriate and acceptable hence promoting early diagnosis and treatment adherence leading to improved quality of life.
A child with a special future! How the understanding of the noun גבר enriches the translation
Authors: Van der Spuy Roelie 
Published: December 2024

Gird your loins and answer God like the ‘hero of faith’ (גבר [geber]) you claim to be! According to some scholars in both divine speeches, God challenges Job to get ready and reply, according to Job’s claim of being a ‘hero of faith’ (גבר [geber]). If it is true that Job is a ‘hero of faith’ (גבר [geber]), then a whole new dimension can be brought to light in the translation of the Hebrew lexeme geber in Job 3:3. This would have profound implications for how to translate Job 3:3 where Job is referring to himself, cursing the night when it was announced that a ‘hero of faith’(גבר [geber]) is conceived! This study contests the claim that this reference would be the only instance in the Bible where גבר [geber] would carry the nuanced meaning of male child, or ‘baby boy’ (NIV). If geber indeed emphasises that Job is a child with a special future, then in most translations, the carefully construed Hebrew emphasis is lost. This relates to most mainline Bible translations, as well as vernacular translations, which just follow suit, i.e. translating Job 3:3 just like previous translations have done.Contribution: The fact that most occurrences of גבר [geber] are in poetic literature helps us to get a fuller understanding of גבר [geber], since that literature uses parallel structures.
Die rol van missionale teologie in die gesprek tussen teologie en filosofie
Authors: Niemandt Cornelius J.P. 
Published: December 2024

The role of missional theology in the conversation between theology and philosophy. The research starts with a brief and concise description of missional theology and missional ecclesiology. For the sake of the local context, the focus is on how the Dutch Reformed Church in South Africa (NG Kerk) articulates these concepts. The broad ecumenical consensus on missional theology is described, including its relevance in discussions within mainstream churches in South Africa, with a brief discussion of denominations that have incorporated missional theology into their theological self-understanding and church praxis. Against this background, attention is given to the central concepts of trinitarian theology (missio Dei), namely incarnation, contextualisation, and inculturation in missional theology. It is attempted to indicate that missional theology intersects with philosophy in various ways, not only in terms of the origin of missional theology (which this research does not address) but especially regarding the nature of missional theology as being sent into the context (world and also philosophy) in which the church finds itself.Intradisciplinary and interdisciplinary implications: This opens up an opportunity to highlight the importance of philosophy for missional theology regarding the following aspects of missional theology: (1) the importance of contextual insight and epistemologically reading the signs of the times; (2) the importance of contextualisation and thus understanding culture and philosophy [zeitgeist]; (3) the importance of a teleological orientation when missional theology inquiries about God’s preferred future; (4) the importance of the communities to which the church is sent and the language used in the conversation; (5) the key function of discernment. The research demonstrates that philosophy is an important and even indispensable conversation partner for missional theology.
Sustainable development goals through the lens of local churches: An interdisciplinary study
Authors: Msebi Mawethu , Beukes Jacques W. 
Published: December 2024

This article reports on the findings of the local churches’ involvement in the Sustainable Development Goals (SDGs) in Tembisa in Gauteng province of South Africa. The article employed Richard Osmer’s model of the four tasks of practical theological interpretation, focussing on narrating and examining the situation in the Tembisa community. The article relied on documentary analysis and in-depth semi-structured interviews. The study findings revealed that local churches could significantly promote the SDGs within their local communities. The study identified essential factors such as human rights, gender equality, peace and justice, and biodiversity conservation as crucial for achieving developmental outcomes. The challenges that local churches face in implementing the SDGs were also discussed.Intradisciplinary and/or interdisciplinary implications: The study outlined principles for ensuring improved quality of life for all through effective implementation of the SDGs. Additionally, the study recommended further empirical research on the role of local churches in promoting SDGs, as well as similar studies in different regions or sectors.
Evaluating NeuroAid’s Effectiveness in Reducing ADHD Symptoms among Saudi Arabia Adolescents: Cross Sectional Study
Authors: Alharbi Ghaiah Jaber , Baowaydhan Rana Khalid , Aldajani Fatima Ahmad , Alqahtani Meshal Mohammed M. , Altuwaijri Haneen Mohammed , Alzahuf Shuruq Mohammed H. , Alawad Fatema Hani , Alhodibi Mostafa Habeeb 
Published: December 2024

Abstract

Introduction:
This research delves into the relatively unexplored area of gaming addiction and attention-deficit hyperactivity disorder (ADHD) symptoms among different age groups. Given the growing concerns around these issues, the study seeks to elucidate the potential relationship between them. The primary aim is to investigate the association between gaming addiction and ADHD symptoms in the Saudi’s population.

Methods:
The study involved a diverse age group, recruited from schools and community centres. Participants were assessed using validated questionnaires designed to measure gaming addiction and ADHD symptoms.

Results:
The analysis revealed a statistically significant positive relationship between video gaming and ADHD symptoms (B = 0.763, 95% confidence interval [CI] =0.633–0.953, P < 0.001). Furthermore, the analysis identified several significant factors. Gender was associated with ADHD symptoms, with a higher odds ratio for males (OR = 1.54, 95% CI = 1.20–1.98, P < 0.001). Education level showed a significant relationship (P < 0.001), where lower levels of education were associated with higher odds of ADHD symptoms. Similarly, employment status significantly impacted ADHD symptoms (P < 0.001), with employment part-time, retirement and student status contributing to varying ORs. Geographic location also had a significant influence (P < 0.001), with urban and rural living showing distinct ORs.

Conclusion:
This study highlights a noteworthy significant positive correlation between gaming addiction and ADHD symptoms. The variation of this correlation with education level and gender underscores the need for tailored intervention and prevention strategies. The findings call for further research to enhance understanding and develop effective approaches to address these issues in the population.
Effects of Exercise on Elderly Heart Health: A Comprehensive Analysis
Authors: Alazmi Abdullah Saleh , Albedaiwi Noor Hamad , Zehefa Ibrahim Ali Mohammed AL , Alhussain Ohud Salman , Magrashi Ebhar Gubran , Alazmi Fahad Adel , Alruwaili Khalid Abdullah , Alamri Yazeed Hassan , Alanazi Ali Farhan 
Published: December 2024

Abstract

Introduction:
Cardiovascular disease (CVD) remains a leading cause of mortality worldwide. Engaging in regular exercise is integral to maintaining cardiovascular health amongst older adults. This study aims to investigate the relationship between physical activity levels, duration and intensity with cardiovascular health amongst Saudi elderly.

Methods:
A cross-sectional study involving 1225 Saudi adults aged ≥65 years was conducted. Data on demographics, physical activity habits, cardiovascular health parameters and medication use were collected through questionnaires. Statistical analyses included descriptive statistics, Chi-square tests and logistic regression to determine associations using SPSS version 27.

Results:
The sample included diverse representation across age, gender, education levels and locations. Most self-reported low physical activity (49.1%) and good cardiovascular health (37.7%). A significant proportion (11.4%) had been diagnosed with cardiovascular complications. High-intensity exercise demonstrated the lowest CVD prevalence (25.3%). Participants who exercised showed significantly lower CVD prevalence than non-exercisers (26.1% vs. 54.3%, P < 0.001). Similarly, individuals exercising ≥5 days/week had the lowest prevalence (35.4%) compared to those exercising less frequently. Through logistic regression, high-intensity exercise, exercising ≥5 days/week and engaging in regular strength training were independently associated with 41%–46% lower odds of CVDs. Self-reported barriers included lack of motivation (17.1%) and perceiving activities as non-challenging (50.9%).

Conclusion:
The study highlights a link between exercise habits and reduced CVD risk amongst Saudi elderly. Promoting high-intensity physical activities conducted regularly could help lower the disease burden. Addressing motivational barriers through educational interventions may encourage exercise adoption to enhance cardiovascular health outcomes in this population.
Quality of Life and Functional Outcomes in Saudi Arabian Head-and-neck Cancer Patients: A Cross-sectional Analysis
Authors: Alharthi Ziyad , Alhawiti Mohammed Eid M. , Alotaibi Ziyad M. , Albalawi Layan Hammad , Alsaleh Danah Abdullah , Alotaibi Jood Khalid , Alshehri Rayan Fahad , Aleid Abbas Fadeil , Alarfaj Abdullah Ahmed 
Published: December 2024

Abstract

Introduction:
Head-and-neck cancer (HNC), a major global health issue, affects the upper aerodigestive tract, with a significant prevalence and impact on patient quality of life (QoL). In the U.S., it ranks as the seventh most common cancer, while Jazan in Saudi Arabia experiences the highest rates, warranting dedicated research. HNC, often linked with risk factors such as tobacco, alcohol and human papillomavirus infections, particularly in younger, healthier populations, leads to a diverse array of symptoms that can severely affect QoL. This research aims to delve into the complex causes of HNC, using a cross-sectional study to assess the QoL and functional outcomes among patients in Saudi Arabia, thereby addressing a noted research gap.

Methods:
A cross-sectional, non-interventional study was conducted from 26 June to 6 August 2023 in Saudi Arabia. We enrolled 1512 patients diagnosed with HNC from several healthcare centres, employing Raosoft’s tools for sample size calculation. The inclusion criteria ensured a sample representative of the population, while the exclusion criteria maintained the study’s focus. Data were collected using the EORTC QLQ-C30 questionnaire and HNC-specific functional outcome tools, ensuring the reliability of psychosocial and physical function assessments. Ethical standards were rigorously followed, with King Faisal University’s approval, and data analysis was performed using SPSS software, with a significance level set at P < 0.05.

Results:
Our findings reveal a substantial impact of cancer stage on patients’ QoL, with interventions such as speech therapy and swallowing exercises showing significant benefits. These results support the hypothesis and align with current literature, indicating the necessity for these interventions in standard treatment protocols. The study also uncovers a correlation between intervention engagement and improved functional outcomes, presenting a case for their inclusion in patient care strategies.

Conclusion:
The study concludes that the stage of HNC is a pivotal factor in determining patient well-being, with therapeutic interventions proving to be beneficial. It emphasises the importance of integrating such therapies into clinical practice and public health policy, potentially shifting current medical protocols. The research lays a foundation for future in-depth studies, aiming to enhance patient care and inform clinical practices. The findings urge healthcare providers and policymakers to consider these insights for improved patient management, advocating for further research to confirm and extend these results.
Incidence and Determinants of Venous Sinus Thrombosis in Saudi Arabian Women: A Cross-sectional Analysis
Authors: Aleid Ahmed Fadeil , Alsaleh Saad Khalid , Alsulayem Reem Ahmed , Alkulaibi Reem , Alfaraj Ahmed Baqer , Alfaraj Samar Emad , Alharthe Mahdi Saeed , Alalweni Bara Talal , Alharbi Hassan Abdulmohsen , Al Mohaini Mohammad 
Published: December 2024

Abstract

Introduction:
The study ‘Incidence and determinants of venous sinus thrombosis (VST) in Saudi Arabian women: A cross-sectional analysis’ delves into the prevalence and risk factors of VST in Saudi Arabian women. This demographic presents unique health factors and lifestyle dynamics, making it a significant focus for understanding the broader implications of vascular diseases in women in the Middle East. The primary research problem aims to ascertain the prevalence and identify risk factors for VST, which is vital for developing tailored preventive and therapeutic strategies and healthcare policies.

Methods:
This cross-sectional study encompassed 1792 Saudi Arabian women, ranging in age, education level and employment status. Participants were selected based on specific criteria, including nationality, gender and age. Data collection methods involved questionnaires, personal interviews and medical record reviews to gather information on health status, lifestyle and medical history. The study used statistical software for quantitative analysis, employing methods like Chi-squared tests to explore associations between VST diagnosis and various factors, including hormonal contraception use and pregnancy history.

Results:
The study’s findings revealed no significant association between hormonal contraception use or genetic predispositions and VST diagnosis. However, a strong association was observed between VST diagnosis and pregnancy-related factors such as the number of pregnancies and complications during pregnancy. These results highlight the importance of understanding specific risk factors for VST, particularly in the context of pregnancy.

Conclusion:
Our research provides new insights into the epidemiology of VST in Saudi Arabian women, challenging some pre-existing notions and reinforcing others. The lack of association with hormonal contraception and genetic predispositions, coupled with the significant association with pregnancy-related factors, underscores the need for tailored healthcare strategies. These findings have profound implications for clinical practice, urging a re-evaluation of current protocols, especially in managing VST risks in pregnant women, and open new avenues for future research.
Potential therapeutic effect of teneligliptin on unpredictable chronic mild stress-induced depression in mice: targeting the role of AMP-activated protein kinase signaling pathway
Authors: Vaghela Ujjval P. , Tirgar Pravin , Maheshwari Rajesh 
Published: December 2024

Background
Depression is a widespread and complex mental disorder that is challenging to treat. The unpredictable chronic mild stress (UCMS) model, based on stress diathesis, is used to study depression because antidepressants often reverse its effects, providing predictive validity. However, the mechanisms behind UCMS are not fully understood. AMP-activated protein kinase (AMPK) is essential for regulating neuronal energy metabolism, and disruptions in its activation can impair brain function and synaptic integrity. Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor with anti-inflammatory, antioxidant, autophagy-modulating, and antiapoptotic properties, has not been studied for its potential to activate AMPK by inhibiting DPP-4, stimulating glucagon-like peptide-1, and decreasing the mammalian target of rapamycin pathway, which may enhance neuroprotection and neurogenesis. This study is the first to show teneligliptin’s potential therapeutic effect on UCMS-induced depression in mice by targeting the AMPK signaling pathway.

Objective
The current study was performed to assess the behavioral, oxidative stress biomarkers, neurotransmitter assay, and histopathology of the brain in UCMS-induced depression in mice.

Materials and methods
Mice were divided into five groups: group I (normal control, received saline), group II (UCMS model with 1 week of stress), group III (UCMS+fluoxetine 10 mg/kg daily for 4 weeks), and groups IV and V (UCMS+teneligliptin 30 mg/kg and 60 mg/kg, respectively, for 4 weeks). Body weight, forced swim test, tail suspension, locomotor activity, oxidative biomarkers (malondialdehyde, reduced glutathione, superoxide dismutase, nitrite levels), neurotransmitters (dopamine, serotonin), and brain histopathology were assessed to evaluate antidepressant activity.

Results and conclusion
Mice treated with teneligliptin (30 and 60 mg/kg) in the UCMS model showed significant weight loss compared with the disease group. They also exhibited reduced immobility in forced swim and tail suspension tests and increased locomotor activity. Significant changes were noted in oxidative stress biomarkers and neurotransmitters (dopamine, serotonin), with improved histopathological conditions. In conclusion, teneligliptin improved behavioral and antidepressant effects by reducing oxidative stress and increasing dopamine and serotonin levels. As a DPP-4 inhibitor, it may activate AMPK in the brain, lower DPP-4 enzyme levels, and enhance glucagon-like peptide-1-R and mammalian target of rapamycin, potentially promoting neurogenesis and neuroprotection, thus being beneficial for depression treatment.
Recurrence patterns-analysis from a South Indian breast cancer patient cohort
Authors: Thumsi Jayanti , Gunda Aparna , Natraj Mallika , Bakre Manjiri M 
Published: December 2024

Abstract

Background:
The current study analyzes the pattern of recurrence/relapse in breast cancer patients belonging to different receptor subtypes to help enhance therapeutic and surveillance methods.

Methods:
This is an observational prospective study of a cohort of 543 patients from South India. Associations between various factors and their significance in relapse were assessed by odds ratio (OR), Chi-square test, and two-sided P value.

Results:
Relapse of cancer in all receptor subtypes was significantly associated with stage III (P = 0.0029). Of the 48 patients who had a relapse of cancer, 42% had relapsed at a distance recurrence (DR), 23% (P = 0.02) had loco/locoregional recurrence (LLR) and the rest had relapsed at distant and loco/locoregional sites. HER2+ (human epidermal growth factor receptor) (83%) and hormone receptor (HR+/HER2-) (77%) patients had higher DR rates with an OR of 2 (95% Confidence Interval, 0.6–6) and 0.47 (95% CI, 0.1–2.1), respectively compared to TNBC (triple-negative breast cancer) patients. TNBCs (80%) had higher LLR rates over HER2+ (50%) and HR+/HER2- (44%) with an OR of 2 (95% CI, 0.6–6) and 2.1 (95% CI, 0.47–9.3), respectively. Bones and lungs in HR+/HER2- patients, liver and lungs for HER2 + patients, and bones in TNBC patients were the preferred sites for metastasis. The number of metastatic sites followed the order, TNBCs > HER2+>HR+/HER2-.

Conclusions:
HR+/HER2- and HER+ patients were more associated with DRs and TNBC patients were associated with LLR. TNBC patients recurred at multiple sites compared to the other two subtypes. Overall, there seems to be a trend in the recurrence across receptor subtypes. Understanding this recurrence pattern will help in enhancing therapeutic and surveillance methods.