bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aplicação dos princípios fair no tratamento de imagens médicas:
Authors: Victor Rodrigues Botão Antonio , Rodrigues Rangel Thayron 
Published: December 2024

Aborda a questão do uso de imagens no ensino da medicina e o reuso do material imagético como recurso didático, visando a implementação da inclusão social. A pesquisa advém de estudo anterior sobre imagens, sua representação e recuperação em sistemas de informação e aprimora-se no tocante ao estudo dos esquemas de metadados descritores de imagens, de imagens médicas e de objetos de aprendizagem. Objetiva demonstrar como a aplicação dos Princípios FAIR no levantamento, descrição e comparação de esquemas de metadados, no ensino da medicina, podem colaborar com a adoção da inclusão social. Apresenta como base as categorias: achável, acessível, interoperável e reusável para a construção das discussões sobre a aplicação da inclusão social e da acessibilidade às pessoas com deficiência. Como procedimentos metodológicos, trata-se de um estudo exploratório de cunho teórico e qualitativo. Para a realização da pesquisa bibliográfica utilizou-se recursos bibliográficos (nacionais e internacionais) e a pesquisa documental em fontes de informação primária, como: atos jurídicos, atos normativos, modelos de acessibilidade, dentre outros . Conclui-se que a falta de um padrão de metadados oficial para o tratamento de imagens médicas e sua adequação aos princípios FAIR no ensino da medicina, deixa o país carente de recursos tecnológicos e didáticos para a otimização da formação inclusiva dos profissionais médicos.
An Exploration of Placement Travel and Accommodation Issues for Nursing, Midwifery and Allied Health Profession Students, Universities, and Practice Educators
Authors: Davenport Sharon , Owoyokun Samson , Fisher Katy , Barker Wendy , Ashcroft Verity 
Published: December 2024

Travel and accommodation challenges for student’s access to pre-registration learning environments were explored through a National Health Service England (NHSE) funded project. This was hosted by XXXX Community Health and Care NHS Foundation Trust covering the XXXXX Integrated Care Board (ICB) area. A mixed methods service evaluation was used, using three cross-sectional surveys to discover local university placement teams, practice education facilitators and practice educators and nursing, midwifery and allied health profession student views on placement transport and accommodation challenges. One student focus group was also held to explore issues in more depth. Stakeholder participants described a range of transport and accommodation concerns, including student personal safety, transport routes, timetable challenges, financial and health burdens, and working to fixed shift patterns. Recommendations for practice include flexible shift patterns, car use guidance, free car parking, personal safety training, provision of overnight accommodation to protect wellbeing, and placement costs paid in advance. The project identified the need for a greater range of bus routes from transport providers, plus consideration for a university minibus service to reach rural community settings. The findings from this study will support placement providers and universities to maximise placement opportunities and will improve the student experience across the ICB setting. The results are applicable to other regions.
MARKETING PERFORMANCE INCREASING WHILE INVOLVING APPLICANTS TO ADMISSION TO THE UNIVERSITY
Authors: Kotsar Oleg , Borichenko Olena , Pobigaylo Vitalii 
Published: December 2024

The professional orientation of applicants is an integral part of the marketing strategy of the universities and the state as a whole to train high-quality specialists for the national economy. The schools and colleges graduates are potential university bachelor's degree applicants. The article presents the experience of involving graduates of schools and colleges for admission to the bachelor's degree at the power supply department of the Igor Sikorsky Kyiv Polytechnic Institute, specialty 141 "Electrical power engineering, electrical engineering and electromechanics" branch of knowledge 14 "Electrical engineering". References 3.
PERFIL CLÍNICO DAS INFECÇÕES EM PACIENTES PÓS-TRANSPLANTADOS DE CÉLULAS-TRONCO HEMATOPOIÉTICAS EM UM CENTRO DE REFERÊNCIA BRASILEIRO
Authors: Rodrigues Afonso Lucélia , Vieira Nobre Stefane , Afonso Júnior Espedito , Carlos da Silva Marcelo Gurgel 
Published: December 2024

Objetivou-se traçar o perfil clínico das infecções em pacientes pós-transplantados de células-tronco hematopoiéticas em um centro de referência brasileiro. Estudo transversal desenvolvido com 71 pacientes submetidos ao transplante de células-tronco hematopoiéticas, em uma instituição pública do estado do Ceará. Os resultados revelaram que 36 (50,7%) eram do sexo feminino, com média de idade de 45 ± 15 anos, 22 (31%) tinham o ensino médio completo, 47 (66,2%) eram casados, 64 (90,1%) eram da cor parda. O tipo de transplante foi o autólogo (49; 59,2%), seguido do alogênico (19; 26,8%). O tipo de infecção predominante foi a bacteriana (71%), seguida da viral (39%) e fúngica (29%). O agente etiológico com maior prevalência foi o Staphylococcus epidermidis. Foi observado que 70% dos pacientes tiveram ao menos uma internação e cerca de 15% tiveram três ou mais internações. O tempo de permanência durante as internações teve uma mediana de 22 dias, com amplitude interquartil de 16 a 37 dias. Além disso foi observado óbito em 28% dos casos. O que o tipo de transplante mais realizado foi o autólogo e os pacientes que possuíam leucemia como doença de base foram os que mais desenvolveram algum tipo de infecção.
Efficiency of different treatment modalities on radiation induced trismus for maxillofacial cases: A parallel randomized clinical trial
Authors: Aboelez Marwa Ahmed , Ibrahim Abdallah Mohammed , ElSawy Mohammed A , El-Khamisy Nermeen El sayed 
Published: December 2024

Abstract

Background
For more than 80% of patients with head and neck cancer, radiation therapy (RT) is a crucial component of their treatment plan which causes impairment for the masticatory apparatus functions leading to trismus. The study objective was to compare the efficacy of of different treatment modalities for patients with RT-induced trismus on patient satisfaction and experience.
Methods
Thirty-six patients with trismus after radiation therapy were classified equally and randomly into three groups (n = 12 per group): Group A was given threaded tapered screw appliance therapy (TTSA), Group B was given low-level laser therapy (LLLT), and Group C was given both threaded tapered screw appliance and low-level laser therapy therapy (LLLT + TTSA). Maximum mouth opening (MMO), visual analogue scale (VAS) and Gothenburg Trismus Questionnaire (GTQ) scores and time required to achieve normal state were evaluated at baseline, 1, 2, 4 weeks, 3 and 6 months after the intervention. Data were collected and analysed using SPSS software
Results
Regarding VAS AND MMO, there was a statistically significant difference at different times of evaluation within all groups where (P < .0001). Regarding GTQ, group C recorded the least values for GTQ symptoms followed by group B followed by group A. Between groups A, B, and C at six months, there was a statistically significant difference for VAS. At week two and one, three, and six months, there was a statistically significant difference between the groups for MMO. There was a statistically significant difference between all groups for all GTQ domines after week two as well as at one, three, and six months.
Conclusion
all available therapy modalities have the potential to effectively improve radiation induced trismus; however, the combination of TTSA and LLLT group appears to yield the most rapid and optimal enhancement.
Clinical Trial Registry Number
(NCT06413628) (2024-03-30)
Study of pollution effects on groundwater caused by modified urea-formaldehyde resin grouting
Authors: Qian Ziwei , Zheng Haobo , Liu Jufeng , He Shenyang 
Published: December 2024

Abstract

It is of practical significance to carry out a study on the pollution effect of typical chemical grouting materials on the regional groundwater quality. A dynamic seepage reaction system was developed, and constant-flow, long-term percolation tests were conducted on two groups: no grouting and urea-formaldehyde resin grouted group. The study found that UF slurry and its reaction products can cause significant pollution damage to groundwater quality, and grout contamination can last for quite some time before completely degrading. UF slurry can affect conventional water quality indicators of groundwater and can alter the water chemistry type of groundwater. The UF grouting process has a significant effect on the ionic content of groundwater. In the process of continuous infiltration, the hydrochemical type of groundwater gradually converges to that of the control group. The water quality indicators and ion content also gradually converge to the values measured in the control group. At the same time, the degradation of the main pollutants from the grouting process shows an exponential decay pattern.
The Effect of Bacterial Inoculation and Organic Amendments for the Establishment of Some Multipurpose Trees on Degraded Land
Authors: Getahun Alemayehu , Muleta Diriba , Kiros Solomon , Assefa Fassil 
Published: December 2024

Abstract

Rehabilitating poor soil can be achieved in part by planting trees. In the field, bio-augmentation and organic amendments (OAs) promote plant establishment and growth. Hence, this study was initiated to assess the role of organic amendments and bacterial inoculations (BI) on tree establishment on degraded soil under field conditions. Six plots measuring 41 m x 4 m were established on which the soil was amended with organic matter and bacterial inoculation (BI) of the transplanted plants quarterly, which were followed by monthly bacterial counts and measurements of plant growth parameters and the survival rate of the plants for one year. Plots receiving OAs showed the highest counts of bacteria (21.66), actinomycetes (2.29), and fungi (0.82) x 105 colony-forming unit g− 1 soil. Also, there were significant (p ≤ 0.05) increases in stem height (1, 0.42, and 0.39 m/plant), girths (12.0, 2.28, and 11.33 cm/plant), and branch numbers (5, 4, and 4.3/plant) on transplanted apple, acacia, and prunus respectively, compared to the control. The highest survival rate was observed on an apple tree (Malus domestica) (80%) and acacia (Acacia abyssinica) (66%). The result concluded that using OAs and BIs enhanced the growth and establishment of trees for the successful rehabilitation of degraded land.
Nest structure and colony composition of two neotropical mound-building termites (Blattaria: Termitidae: Nasutitermes coxipoensis and Cortaritermes intermedius)
Authors: Mendoza Ato , Starr Christopher K. , Arneaud Linton L. 
Published: December 2024

Abstract

On the island of Trinidad, West Indies the mound-nesting Nasutitermes coxipoensus and Cortaritermes intermedius (Nasutitermitinae) are each only known from one distinct savanna habitat. The former builds larger nests that harbourlarger colonies. Consistent with what is known from other nasutitermitines, the proportion of soldiers in the colony is high in each species: 11-15% of adults in most N. coxipoensis and 7-19% in C. intermedius colonies. While this shows no correlation with overall colony size in N. coxipoensis, we found a negative correlation between these two parameters in C. intermedius. Consistent with what has been found in some mound-nesting fungus-gardening termites (Macrotermitinae), mounds of both species showed a higher concentration of some elements and organic matter than in the surrounding surface soil.
Opposing effects of rewarding and aversive stimuli on D1 and D2 types of dopamine-sensitive neurons in the central amygdala
Authors: Beroun Anna , Bijoch Łukasz , Szczypkowski Paweł , Wiśniewska Justyna , Pawłowska Monika , Hajdukiewicz Karolina , Łapkiewicz Radosław 
Published: December 2024

Abstract

Dopamine-sensitive neurons are organized in two classes of cells, expressing D1- or D2- types of dopamine receptors, and are often mediating opposing aspects of reward-oriented behaviors. Here, we focused on dopamine-sensitive neurons in the central amygdala – a brain structure critically involved in processing emotion-related stimuli. Exposing mice to rewarding and aversive stimuli we studied DRD1 and DRD2 cells activity using in vivo two-photon calcium imaging in the CeM. We showed that cocaine and sugar predominantly increase the activity of DRD1(+) neurons and decrease DRD2(+) cells. Repeated exposure to cocaine, however, had the opposite effect on spontaneous excitatory synaptic transmission in the CeM than exposure to sugar. Quinine, an aversive stimulus, primarily engaged DRD2(+) neurons, activating predominantly those cells that were previously inhibited by sugar exposure. Our results show that though DRD1 and DRD2 populations are differentially engaged and regulated by appetitive/aversive stimuli, both participate in sugar, cocaine, and quinine processing.
Geoinformatics and AHP-MCDM integrated flood hazard zone mapping over Modjo catchment, Awash River basin, central Ethiopia.
Authors: Bedada Bereket , Dibaba Wakjira 
Published: December 2024

Abstract

Floods are natural disasters that profoundly influence the environment and society. To effectively control the incidence of flooding, it is crucial to identify and map regions susceptible to flooding. This study aimed to identify and locate the flood risk zones of the Modjo catchment employing the integrated use of multi-criteria decision-making and geoinformatics tools. Ten influencing factors were used to develop flood risk zones: drainage density, curvature, rainfall, distance from the river, soil type, elevation, slope, topographic wetness index, land use/cover, and the normalized difference vegetation index. Subsequently, raster-formatted thematic layers of these influencing elements were created, and appropriate weighting was assigned based on their relative responses to the occurrence of flood events and overlayed using the overlay GIS spatial analysis tool. The flood risk potential zone in the study area was generated and classified into five groups: negligible, low, intermediate, high, and severe. According to the results, the negligible, low, intermediate, high, and severe zones were represented by 0.686% (9.74 km2), 74.12% (1052.28 km2), 8.44% (119.94 km2), and 0.0012% (0.018 km2), respectively. The weighting and ranking processes are well reflected in the final flood risk zone map. The results revealed that a substantial area of the catchment is at risk. Ultimately, 28 historical flood datasets were used to confirm the outcome, yielding an accuracy of > 75% and an area under the ROC curve of 0.868. Most of the flood point data were found in high and severe regions. Considering the verified results, relevant organizations should participate in creating sustainable management plans.
Long-term treatment with recombinant human growth hormone in pediatric patients with growth hormone deficiency influences but does not destroy stem cells circulating in blood
Authors: Wedrychowicz Anna , Sielatycka Katarzyna , Kucia Magda , Kubis Ewa , Roztoczynska Dorota , Starzyk Jerzy B. 
Published: December 2024

Abstract

Very small embryonic/epiblast-like stem cells (VSELs), found in circulating blood are small, non-hematopoietic cells expressing markers of pluripotent embryonic and primordial germ cells. VSELs are responsible for postnatal tissue and organ rejuvenation. For the first time we performed long-term observations of VSELs in response to growth hormone (GH) therapy in pediatric patients. Enrolled 20 patients aged 5.2–13.4 with GH-deficiency were monitored periodically for first year of GH treatment. Eight of them were examined again after eight years of continuous GH therapy. Selected stem cells were analyzed in peripheral blood flow cytometrically. The number of 34 + VSELs was higher than baseline and the number of 133 + VSELs was comparable to the baseline number after long-term therapy. The increase in VSELs number paralleled the increase in circulating hematopoietic stem cells, mesenchymal stem cells (MSCs) and endothelial progenitor cells. We found a significant, positive correlation between VSELs and MSCs, moreover both 34 + VSELs and MSCs positively correlated with postprandial glucose. Our data confirm that VSELs respond to GH treatment. Long-term therapy with GH modulates but did not damage, even improves the population of VSELs in GH-deficient patients. Therefore in contrary to experimental animals GH therapy seems not damage life span and organ rejuvenation in patients.
Essential oils biosynthesis is differentially regulated at different developmental stages of Curcuma longa L.
Authors: Majaw Teikur , Bharti Sanjan Kumar , Mishra Ashim K 
Published: December 2024

Abstract

Essential oils (EO) are plants secondary metabolites significant for plant’s defense and supplementary growth. These are synthesized in plants cells in response to various factors. Here, we demonstrate that essential oils extracted from leaves of Curcuma longa are differential expressed at different developmental stages. The EO yield was 1.13% at 4-month old, 1.79% at 6-month and 1.35% at 8-month old leaf in Rajendra Sonali variety. In the variety, Narendra Haldi, the essential oils yield was 0.81% at 4-month old, 1.75% at 6-month and 1.08% at 8-month old leaf. The number of compounds were 45, 41 and 42 in Rajendra Sonali and 47, 33 and 40 Narendra Haldi leaves at 4-, 6- and 8-month old leaves. Monoterpenes were the most abundant followed by sesquiterpenes. Terpinolene, accounts the highest component at 27.62%, 24.7% and 24.7% in Rajendra variety while it is 30.57%, 36.01% and 11.36% in Narendra haldi (NH) at three different stages. Differential genes expression showed that genes involve in biosynthesis of essential oils were highly expressed in 6-month old leaves. Most of the genes that acts as feeder pathway to EO biosynthesis such as carbohydrate metabolism are highly expressed in 6-month old leaves. The finding suggest that the essential oil content and chemical composition is due to the differential expression of genes involving in the essential oil biosynthetic pathway and the differential components may be used as a metabolic marker of developmental stages.
Growth Performance and Nutrient Removal Efficiency of Chlorella Vulgaris in Fish Wastewater for the Cuban Agro-Industrial Sector
Authors: Sorí Lilyana Carbonell , Garciga Julio Pedraza , Rivero Néstor Armando Carbonell , Davila Edelbis Lopez 
Published: December 2024

Abstract

Purpose
The study aimed to evaluate the growth capacity and nutrient removal efficiency of Chlorella vulgaris in fish wastewater (FWW) and Bold's Basal (BB) medium as a control. The research question was whether C. vulgaris could grow and remove nutrients in FWW effectively.
Methods
The experiment was conducted under controlled conditions in a climatic chamber. C. vulgaris was grown in FWW and BB medium. Cell counting, optical density, and dry weight were measured daily. The nutrient removal efficiency was determined by analysing total nitrogen (TN) and phosphate (P-PO43−) concentrations.
Results
The growth of C. vulgaris in both media was gradual, with an exponential phase from day 2 to 10 in BB medium and from day 4 to 10 in FWW. TN removal reached 89.5% in BB and 92.1% in FWW, while P-PO43− removal was 78.9% in BB and 84.2% in FWW.
Conclusion
C. vulgaris demonstrated efficient growth and nutrient removal in fish wastewater, making it a promising candidate for wastewater treatment and biomass production in the Cuban agro-industrial sector.
Effect of Chinese Traditional Exercise on Reducing Fall Risk among Aging People: a single-blind randomized trial
Authors: Lu Jiali , Li Jiahao , Ren Shuangfeng , Yang Huizhi , Chai Xinyu , Yan Huiping , Shan Wei , Lu Yifan 
Published: December 2024

Abstract

This study was designed to determine the effect of 12 weeks of the Chinese traditional exercise, the Dao Yin Regime on reducing fall risk in aging population (>60 years).
The exclusion criteria for individuals were as follows: 1) were under 60 years; 2) were unable to read and write; 3) had any acute cardiovascular disease in the past month; 4) had any diagnosed disorder of balance function; 5) had visual problems; 6) had hearing problems; 7) had taken drugs that could lead to dizzy. 8) had regular exercising over 6 months. We novelly tried not to exclude people who take sleeping pills since it has already become a normal phenomenon, we also stipulated that people who live alone should be considered serious issues. We planned to recruit 90 people by calculating at the beginning, but in the end, 93 participants were recruited. Every person received a complete fall risk screening process and they were divided into low-risk (30), moderate-risk (29), high-risk (34) based on the STEADI screening toolkit. The age features in each group were: 80.63±6.83(low-risk),83.38±5.89(moderate-risk) and 82.12±5.64(high-risk), and the sex distribution were: male:14(45.16%) and female:17(54.84%) in the low-risk group, male:8(27.59%) and female:21(72.41%) in the moderate-risk group, male:9(26.47%) and female:25(73.53%) in the high-risk group.
The exercise program was set 90min in every training session, and was repeated 3 times a week. Every training session started with 10 min warm-up activity, followed by the standing training, which lasted approximately 40 min, and the last was dynamic training, which contained 12 movements lasting 40 min, with a 5 min cool down activity in the end. The entire training program lasted 12 weeks.
The methods to evaluate of the effects included demographic, physiological, and psychological aspects, gait characteristics were the main indices used to assess the effects, the within- and between-group differences were analyzed via paired t-test and chi-test. In the gait characteristics, only the low-risk group showed distinct decline in TUG test (p<0.01). The precise reason of why this outcome was not clear, but there was a small improvement in the participants’ physical function and also the frailty situation improved.
In this study, we found that low educational background was not an essential issue on increasing fall risk for old people(p<0.01). Since this was the first attempt on investigate the effect of the Dao Yin Regime on reducing fall risk among old people, some limitations remain, and more studies are needed.