bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dificuldades enfrentadas por lésbicas, gays, bissexuais, travestis, transexuais e transgêneros ao atendimento no Programa de Saúde da Família
Authors: Santos Edilson Lima dos , Prigol Adrieli Carla , Lasmar Sonyara de Araújo , Zandoná Nathalia Sanvido 
Published: August 2020

Objetivo: investigar a produção científica acerca das dificuldades enfrentadas por lésbicas, gays, bissexuais, travestis, transexuais e transgêneros ao atendimento na saúde pública. Metodologia: utilizou-se de um estudo de revisão narrativa, a partir da questão norteadora da pesquisa: Quais as principais barreiras/dificuldades enfrentadas por esse público ao acesso a saúde pública? Resultados: foram encontrados um total de 16 publicações, destes foram selecionados 13 que tinham seus títulos relacionados com a temática proposta. Discussão: tratando-se da população LGBT, no acesso ao trabalho educação e saúde, acentua-se a discriminação pelo fato dessa minoria não se enquadrarem nos padrões estipulados por uma sociedade conservadora. Considerações Finais: o acesso desse grupo populacional aos serviços públicos de saúde é limitado, permeado por omissão, intolerância, constrangimentos e posicionamentos éticos e excludentes. Apesar de estratégias de enfrentamento das iniquidades e desigualdades, implantadas pelo Sistema Único de Saúde, ainda requer aperfeiçoamento e principalmente sensibilização dos profissionais que atendem essa população.
Effects of Zanthoxylum caribaeum essential oil against cotton bug Dysdercus peruvianus
Authors: Pacheco João Pedro Furtado , Nogueira Jeane , Miranda Rodrigo Prado Rodrigues de , Duprat Rodrigo Coutinho , Machado Francisco Paiva , Tietbohl Luis Armando Candido , Mourão Samanta Cardozo , Santos Marcelo Guerra , Ratcliffe Norman Arthur , Penna Patricia Azambuja , Mello Neto Cicero Brasileiro de , Rocha Leandro , Gonzalez Marcelo Salabert , Feder Maria Denise 
Published: August 2020

Agricultural crops need protection from a variety of different insects popularly known as pests. Some of these pests are becoming increasingly resistant to conventional pesticides, so new control alternatives are needed. In this work, the effects of the essential oil of the plant Zanthoxylum caribaeum on the development of cotton stink bug Dysdercus peruvianus were analyzed. After analysis by chromatography and mass spectrometry, the essential oil of Z. caribaeum presented 54 substances, the main constituents being Sylvestrene, Muurola-4 (14), 5-trans-diene, Isodaucene and α-Pinene. These compounds significantly increased insect mortality and interrupted metamorphosis and molting, often in a dose-dependent manner. In addition, nymphs with deformed legs, wings and antennae were observed. According to the data, the components present in the essential oil of Z. caribeum appear to be promising candidates for the development of green insecticides for use in future integrated pest management (MIP) programs.
KONSEP ‘IDDAH DENGAN MENGGUNAKAN TES KEHAMILAN PERSPEKTIF MAQASIDUS SYARI’AH
Authors: AINUR ROFIQ  
Published: August 2020

‘Iddah disyari’atkan bagi perempuan tersebut karena dalam hukum ‘Iddah mengandung banyak kemaslahatan yang kembali kepada suami, istri, keluarga dan masyarakat. Kemaslahatan ‘Iddah untuk melindungi dan memelihara keturunan dari ketercampuran dengan laki-laki lain yang akan dinikahi. Sebab, kesucian seorang perempuan selama masa ‘Iddah tanpa menikah dapat diketahui dari kebebasan dan kekosongan rahimnya dari adanya janin yang ada dalam rahimnya. Perkembangan zaman, ilmu pengetahuan dan teknologi yang canggih, hasil- hasil yang dicapai oleh Ilmu Pengetahuan dan Teknologi (IPTEK) ini luar biasa. Berkat kemajuan teknologi dalam bidang kedokteran dan juga rekayasa manusia yang sangat mengagumkan, kebersihan rahim seorang perempuan dapat diketahui melalui alat tes kehamilan Tespack (Home Pregnancy Test). Tespack bekerja dengan cara mendeteksi hormon HCG (Human Chorionic Gonadotropin) yang terdapat pada urin. Dan hanya dengan menunggu beberapa menit saja rahim seorang wanita dapat diketahui apakah di dalamnya terdapat janin atau tidak dengan tanda positif maupun negatif.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GANGGUAN POLA TIDUR PADA PERAWAT DI INSTALASI RAWAT INAP BAGIAN D3 RSUD CIBABAT TAHUN 2014
Authors: Mauliku Novie Elvinawaty 
Published: August 2020

Gangguan pola tidur merupakan suatu kondisi dimana seseorang mengalami resiko perubahan jumlah dan kualitas pola tidur yang menyebabkan ketiadanyamanan diantaranya Insomnia, Hypersomnia, Narkolepsi, Parasamnia, Suden Infant Death Syndrome. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan gangguan pola tidur pada perawat di Instalasi Rawat Inap bagian D3 RSUD X.Penelitian ini menggunakan desain penelitian cross sectional. Metode pengambilan sampel dengan teknik total sampling. Yang terdiri dari variabel shift kerja, masa kerja, konsumsi kafein, penggunaan obat tidur, dan kebiasaan merokok. Pengumpulan data dilakukan dengan menggunakan kuesioner dan data dianalisis secara Univariat dan Bivariat dengan uji chi square.Hasil analisis data didapatkan sebesar 50% perawat mengalami gangguan pola tidur, dan hasil uji statistik diketahui terdapat hubungan antara shift kerja (0.022), masa kerja (0.028), dan konsumsi kafein (0.0001) dengan gangguan pola tidur. Sedangkan variabel yang tidak berhubungan yaitu penggunaan obat tidur (0.109), dan kebiasaan merokok (1.000). Disarankan agar para perawat yang memiliki gangguan pola tidur agar berperilaku hidup sehat, perawat mendahulukan mengkonsumsi makanan yang bergizi, dan pihak rumah sakit mengadakan kegiatan olah raga rutin bagi perawat minimal 30 menit dalam seminggu.
BIRD FLU – COUNTER-STRATEGY
Authors: Avdosieva I. K. , Kalinina O. S. , Chaikovska O. I. 
Published: August 2020

The rapid growth of international cooperative ties poses a serious threat to the spread and spread of one of the few yet the most dangerous infections on the territory of Ukraine – bird flu. In addition to the economic damage caused by this disease to the poultry industry, an important aspect is the danger to human health and the potential risks of a new pandemic variant of the virus. The epizootic situation of this disease remains complex recently and cases are reported in most developed poultry countries
The article provides analytical material on HPBF outbreaks in 2018-2019. In 2018 the HPBF was registered in 39 countries and outbreaks ranged from 1 to 110 and the highest in Taiwan were – 110, Russia – 82, Egypt – 49, Bulgaria – 29. In 2019 HPBF outbreaks were registered in 19 countries and ranged within from 1 to 107 and the highest number was in Taiwan – 107, Mexico – 35.
At present, there is a very difficult epizootic situation in the world for flu viruses caused by the following subtypes: H5N1, H5N2, H5N3, H5N5, H5N8, H5N9.
During 2018 registered strains of HPBF in the countries of the world were: N5 – 22; H5N1 – 16; H5N2 – 25; H5N3 – 2; H5N5 – 0; H5N6 – 8; H5N8 – 26; H5N9 – 1. During 2019, registered strains of HSVP in the countries of the world were harboring: N5 – 1; H5N1 – 10; H5N2 – 48; H5N3 – 17; H5N5 – 3; H5N6 – 4; H5N8 – 16; H5N9 – 0 %.
With regard to low pathogenic avian influenza (LPBF), their worldwide wide circulation in the natural reservoir has been proven to date. In 2019 the highest number of LPBF outbreaks caused by different strains was: H5N1 – 36; H7N3 – 29 and H5N2 – 22. During 2019, the reported LPBF strains in the countries were: H5 – 6; H5N1 – 34; H5N2 – 21.1; H5N5 – 0; H5N6 – 4; H5N8 – 0; H7N3 –; H7N4 – 3; H7N9 – 1; H7N5 – 2; H7N6 – 1 %.
The use of the following antiviral medications for the prevention and treatment of LPBF revealed their high therapeutic and prophylactic significance, namely: remantadine, amizone, aminocaproic acid and made on the basis of modern nanotechnologies – Germacap. Due to the 2-time (with an interval of 7 days) use of remantadine aerosol for prevention of LPBF epizootic among ducklings, the conservation of livestock reached 93 %, whereas in control – only 37 %. When treated with remantadine, the young growth of egg crosses for therapeutic purposes resulted in a 45 % reduction in the discharge of livestock against control by reducing death and culling.
INFLUENCE OF ARSIL FEED ADDITIVE ON HEMATOLOGICAL INDICES, PRODUCTIVITY AND STRUCTURE OF INTERNAL ORGANS BROILER CHICKENS
Authors: Zhyla M. I. , Mykhalus G. M. , Maksymovych O. A. , Lapin O. V. , Mykhalyuk O. V. , Haziiev A. R. 
Published: August 2020

Poultry farming using modern technologies requires the employment of veterinary preparation for the prevention of infectious diseases and also feed additives for the improvement of metabolic functions and correction of body resistance.
The article presents the results of clinical trials of feed additives in the form of an ionic solution concentrate of the biologically active nanosilicon "Arsil". The clinical study was performed on healthy ten-day-old broiler chicken, cross "Cobb-500", organized into three groups of 20 heads each: Group I received a feed additive at a dose of 0.5 ml per 1 liter of water, group II – at a dose of 1.0 ml per 1 liter of water and group III was the control group (on a regular diet, without feed additives). The use of the studied feed additive was carried out by watering with water for 30 days. Poultry of all groups were fed with identical feeds in accordance with regulatory requirements taking into account the age of the bird. The clinical condition of the bird was monitored daily, control weightings were performed once a week and blood samples were taken for laboratory tests on days 15 and 35 of the experiment. At the end of the experiment, a diagnostic slaughter of birds of all groups and a complete pathological autopsy with selection of material for histological examination were performed.
Studies have shown that the use of the feed additive "Arsil" contributed to weight gain and average daily gain, improved the feed conversion and the tendency for the growth of the concentration of hemoglobin, hematocrit and erythrocytes in broiler chicken from the experimental groups compared with the control group at the end of fattening. The structure of the internal organs of birds of all studied groups is preserved, macroscopic changes in organs and tissues are not detected. An increase in the coefficients of mass of immune-competent organs in broiler chicken fed the feed additive "Arsil" compared with the control group was found.
RELATIONSHIP BETWEEN ANIMAL PRODUCTIVITY AND CONTENT OF SOME MACRO- AND MICROELEMENTS IN DIFFERENT FRACTIONS OF COW'S BLOOD BY ASSIGNMENT OF FEED ADDITIVE GERMATZINK
Authors: Zhurenko O. V. 
Published: August 2020

The high productivity of dairy cattle, while keeping the ability to adapt and ensure the basic physiological functions of the body, creates the conditions for profitable milk production and efficient animal usage. The development and implementation of selective improvement of breeds and types methods requires the study of biological features of cattle, adaptive parameters of its productive potential. The studies were conducted on the farm of Vinarivka village of Kyiv region. The types of HNA were determined by the method of food conditioned reflexes. Four experimental groups were formed by the results of the conditioned reflex study. The cows of the experimental group feed additive “Germatsink” was applicated at a dose of 10 ml/day within 30 days. Animals in the control groups (with different types of higher nervous activity) received a standard diet. The goal of the study was to determine the correlation between productivity and the content of some macro- and microelements in the serum and blood cells of cows after feed additive “Germatsink” application. Studies have shown that Germatsink application leads to changes in the relationship between productivity and the content of some minerals in the cows’ serum. However, there was weak correlation between phosphorus and calcium in the serum and average daily yield (r = 0.41; p <0.05), and significant relationship to the content of potassium, magnesium and lithium is disappear. It was found strong correlation between content of potassium, magnesium and cuprum in serum and fat content of milk of these animals.
In 30 days after Germatsink was administered, the calcium (r = -0.48; P <0.01) and Zinc (r = 0.39; P <0.05) content was related with milk yield in cows. It was noted a change in the relationship between the quality of milk and the content of some elements in the blood cells of cows. In particular, increase of relationship between content of magnesium (r = 0.52; P <0.001), zinc (r = 0.48; P <0.01), cooper (r = 0.38; P <0.05) and fat content of animal’s milk.
TURNOVER OF ANTIMICROBIAL VETERINARY MEDICINAL PRODUCTS IN UKRAINE AS A FACTOR OF THEIR RATIONAL USE IN THE TREATMENT OF INFECTIOUS DISEASES IN ANIMALS
Authors: Kosenko Yu. M. , Ostapiv N. V. , Zaruma L. E. 
Published: August 2020

The procedure for manufacture, sale and rational use of antimicrobial veterinary medicinal products in veterinary medicine must comply with the national legislation, namely the Law of Ukraine “On Veterinary Medicine”. Only authorized in Ukraine veterinary medicinal products have been used in veterinary medicine as required with the recommendations stated in package leaflet, labeling and summary of the product characteristic. The article describes main principles of monitoring process sales turnover of antimicrobial veterinary medicinal products during period of study 2015-2018.
On the suggestion of the World Organization for Animal Health (OIE) at the beginning of 2016 Ukraine started collecting annual sales data (for the previous year) on antimicrobial veterinary medicinal products in food-producing and domestic animals in accordance with the Chapter 6.9. of the Terrestrial Animal Health Code, 2016; 2018.
The main goal of this study was the implementation of OIE recommendations in monitoring process by the assessment of sales patterns of antimicrobials, their influence on prudent use, in compliance with Ukrainian National Action Plan Tackling Antimicrobial Resistance, 2019. The study was conducted during four 12-month periods (from January 1 to December 31) during 2015-2018. The data in questionnaires reports were received from marketing authorization holders and distributors and collected as suggested by OIE. The specification of the amounts of the antimicrobials annual sales during 2015-2018 according route of administration and antimicrobial classes in [kg] and [%] of active ingredient were presented.
The study revealed the main high-selling classes of antimicrobials (Tetracyclines, Penicillins and Sulfonamide+Trimethoprim); the commonly used route of administration (oral ~ 90 %) and part of veterinary critically important and important antimicrobials in total sales amounts of all antimicrobial veterinary medicinal products. Macrolides occupied the main part (10,2 %) in veterinary critically important antimicrobial medicinal products; part of Aminoglycosides was ~ 4 %; Fluoroquinolones – among 2,5 - 7,14 % and part of Cephalosporins was less than 1% during all years of the study.
This study can be considered as the first step towards implementation a national monitoring system for rational and prudent use of antimicrobials in veterinary medicine.
THE INDICES OF MILK QUALITY, REPRODUCTION, BLOOD AND RUMEN LIQUID IN HIGHLY PRODUCTIVE COWS IN THE FIRST PERIOD OF LACTATION FOR FEEDING OF MIXED-LIGANDE COMPLEXES OF ZINC, MANGANESE AND COBALT
Authors: Kropyvka Yu. G. , Bomko V. S. 
Published: August 2020

The article presents data on milk productivity, reproductive function and chemical composition of milk, as well as hematological parameters of blood and rumen liquid in high-yielding Holstein cows of German selection, Ukrainian black-spotted dairy and Ukrainian red-spotted dairy breeds in the first lactation period for feeding them different doses of mixed-ligand complexes of Zinc, Manganese and Cobalt.
It is established that the use of mixed-ligand complexes of Zinc, Manganese and Cobalt in the feed mixture in comparison with their sulfates has a positive effect on milk productivity and reproductive function of cows and the chemical composition of their milk, and feed costs decrease with increasing productivity.
The use of different forms and levels of Zinc, Manganese and Cobalt in the diets of experimental cows affected protein and carbohydrate-fat metabolism and the best results were obtained when using different levels of these trace elements in the feed due to their mixed-ligand complexes.
In the rumen liquid of experimental cows, the pH value increased in the alkaline direction and the difference to the control group was statistically significant. There was also a tendency to increase residual nitrogen compared to control. There was a significant difference in the reduction of ammonia nitrogen in the rumen liquid of cows of experimental groups, which indicates better use and assimilation of crude protein.
The best indicators of milk productivity, chemical composition of milk, reproductive function, blood and rumen liquid were obtained when using mixed-ligand complexes of Zinc, Manganese and Cobalt in the feed mixture when the concentration of these trace elements in 1 kg of DM was, mg: Zinc – 60.8; Manganese – 60.8; Cobalt – 0.78; Selenium – 0.3; Copper – 12 and Iodine – 1.1. This concentration of trace elements was achieved due to their mixed-ligandent complexes, copper – its sulfate, iodine – potassium iodide, selenium – selenium suplex.
THE INFLUENCE OF CADMDIUM LOAD ON THE LEVEL OF VITAMINS A AND E IN BLOOD OF LAYING HENS
Authors: Ostapyuk A. Y. , Gutyj B. V. 
Published: August 2020

Cadmium – a heavy metal, classified as a second class of danger, has a pronounced tendency to accumulate in the body. Absorbed cadmium accumulates in the liver as a complex with metallothionein. The aim of the study was to study the effect of Cadmium on the level of vitamins A and E in the blood of laying hens. For research, three groups of poultry were formed: control and two experimental. The control group chickens were on a regular diet, fed with compound feed and drinking water without cadmium sulfate. To drinking water of chickens of experimental groups for 30 days was added cadmium sulfate in doses: the first group – 2 mg/kg, the second group – 4 mg/kg of body weight. The keeping conditions of the chickens and the indoor microclimate parameters for all groups of birds were similar.
After cadmium loading at a dose of 2 mg/kg body weight, the level of vitamin A in the blood of chickens has probably decreased since the 14th day of the experiment. It was the lowest at 21 days of experience. When drinking cadmium sulfate at a dose of 4 mg/kg body weight decreased levels of vitamin A by 4 and 21 days of the experiment, respectively, by 24 and 40% compared with the control group of chickens.
When examining the level of vitamin E in the blood of laying hens under cadmium loading, it was found that in the second experimental group of chickens the level of this vitamin was significantly lower than in the control and the first experimental group of chickens. When compared with the control group of chickens, it was found that on the 14th day of the experiment, the level of vitamin E was lower in the first experimental group by 12% and in the second – by 27%, respectively. At day 21 of the experiment, the level of vitamin E was the lowest in the second experimental group, where it was 0.70 ± 0.011 µg/ml, respectively, which is 44% lower than the control.
A significant decrease in the content of vitamins A and E indicates not only the pathological condition of the liver, but also the enhancement of oxidation processes associated with a decrease in the activity of enzymes of the antioxidant system. Cadmium compounds have high biological activity, they easily form complex compounds with proteins, nucleic acids, which inactivate a number of enzymes.
MACROSCOPIC CHANGES IN EXPERIMENTALLY DAMAGED TIBIA OF RABBITS WHEN ALLOGENEIC MESENCHYMAL STEM CELLS WERE INTRODUCED IN DIFFERENT WAYS
Authors: Savchuk T. L. , Bokotko R. R. , Kharkevych Yа. О. , Mazurkevych A. Y. , Malyuk M. O. , Danilov V. B. , Blahyi R. S. , Braha O. V. 
Published: August 2020

The article presents the results of studying macroscopic changes in the tibia of rabbits during experimental mechanical damage after leading allogeneic mesenchymal stem cells to the jugular vein and directly to the site of bone damage.
Bone damage was modeled on 3-month-old chinchilla rabbits in the middle third of the tibial shaft. Macroscopic studies of the process of restoration of the tibial defect were carried out on 3, 7, 14, 21, 28 and 42 days. Our macroscopic studies of the healing of a tibial defect indicate a difference in the regeneration processes in rabbits of the control group and experimental groups after the use of allogeneic mesenchymal stem cells.
It was found that the introduction of allogeneic mesenchymal stem cells, regeneration processes are faster for 3 days in the area of damage, there are no blood clots, and in the subsequent phases of regenerative osteogenesis, the reaction of adjacent soft tissues, the formation of bone corns and its reduction in volume, accelerated. Almost complete restoration of the defect due to the introduction of allogeneic mesenchymal stem cells occurs on the 28 day. While in the control group of animals, it ends only at 42 days.
In addition, it was found that the introduction of allogeneic mesenchymal stem cells directly to the site of injury regeneration processes in the area of the created bone defect are more intensively expressed in the first and subsequent phases of regeneration than in animals after the use of allogeneic mesenchymal stem cells intravenously.
The obtained data can be used to restore damaged bone tissue using stem cells, as well as for further experimental studies.
DIETARY IMPACTS ON EARLY RUMEN MICROBIOTA DEVELOPMENT IN CALVES
Authors: Shkromada O. I. , Ulko L. G. , Udovenko Ya. S. 
Published: August 2020

The rumen is an important digestive organ in which fermentation processes take place. Improving the rumen development of growing cattle is one of the major tasks. The need for ruminants in amino acids is as great as in mono-gastric animals. The rumen microorganisms cannot synthesize microbial protein in sufficient quantity to cover the need of developmental growth.
The experiments were conducted on calves from four to five months of age at the «Za myr» farm in Sumy district, Sumy region. The calves were divided into three experimental groups of 10 animals each. The first experimental group was fed powder not protected methionine at a dose of 10 grams per animal, the second group was fed granulated methionine at a dose of 10 grams per animal for a month.
The results suggest that bacterial count increased by 84,3%; Paramecium caudatum by 29,4 %; Entodiniomorpha by 26,6 % in the first experimental group to the 30th day. In the second group the indicators also changed after a month of research. The bacterial count was 93,2 % higher; Paramecium caudatum by 42,5 %; Entodiniomorpha by 25,9 % compared to control.
According to the results of the experiment, we can assumed that powder methionine as well as granular had a positive effect on the qualitative and quantitative composition of the rumen microflora. In the first experimental group content of total nitrogen was higher by 12,2 % and protein content by 19,6 % compared to controls. In the second experimental group, where calves were fed a granulated methionine, content of total nitrogen was higher by 15,6 % and protein content by 22,4 % compared to controls. The residual nitrogen concentration significantly decreased by 32,2 % in the first group of calves and by 29,9 % in the second.
It was experimentally proved that the enriched of granulated and non-granulated methionine food additives helped to increase the number of microorganisms in the rumen and increase the concentration of nitrogen in the rumen.