bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic performance of coronal view in comparison with transverse view of three-dimensional automated breast ultrasound
Authors: Suzuki Megumi , Nakayama Ryohei , Namba Kiyoshi , Kawami Hiroyuki , Nara Mayumi , Smathers Ralph L , Nakamura Seigo 
Published: April 2020

Background Automated breast ultrasound (ABUS) is one of the first ultrasound devices which enables the de-coupling of image acquisition and interpretation. Another feature of ABUS is the coronal view, utilizing three-dimensional volume data reconstructed from two-dimensional transverse images acquired automatically. Purpose To assess the diagnostic performance of coronal view interpretation by comparing it with that of the transverse view. Material and Methods This was a retrospective, multi-case, observer study using a cancer-enriched dataset of ABUS images at a single institution with approval by an Institutional Review Board. The 100 scan datasets selected between October 2014 and January 2017 included 70 non-cancer cases and 30 malignancies. In the present observer study, two experienced physicians provided their confidence levels regarding the malignancy of each of the 100 scan datasets independently. The reading times for interpretation of coronal and transverse views were recorded. Results Area under the receiver operating characteristic curves for two observers with the transverse view (0.856) was improved by use of the coronal view (0.917, P = 0.036). The average reading times were 140.4 s with the coronal view and 148.5 s with the transverse view per scan dataset ( P = 0.246). Conclusion It is conceivable that the accurate use of the coronal view will lead to improvement in diagnostic performance in breast cancer screening, although this needs to be confirmed with a larger prospective study.
Community initiated kangaroo mother care and early child development in low birth weight infants in India-a randomized controlled trial
Authors:   for the ciKMC development study group, Taneja Sunita , Sinha Bireshwar , Upadhyay Ravi Prakash , Mazumder Sarmila , Sommerfelt Halvor , Martines Jose , Dalpath Suresh Kumar , Gupta Rakesh , Kariger Patricia , Bahl Rajiv , Bhandari Nita , Dua Tarun 
Published: April 2020

Abstract
Background
In a randomized controlled trial (RCT) with 8402 stable low birthweight (LBW) infants, majority being late preterm or term small for gestational age, community-initiated KMC (ciKMC) showed a significant improvement in survival. However, the effect of ciKMC on neurodevelopment is unclear. This is important to elucidate as children born with low birth weight are at high risk of neurodevelopmental deficits. In the first 552 stable LBW infants enrolled in the above trial, we evaluated the effect of ciKMC on neurodevelopmental outcomes during infancy.

Method
This RCT was conducted among 552 stable LBW infants, majorly late preterm or term small for gestational age infants without any problems at birth and weighing 1500–2250 g at birth. The intervention comprised of promotion of skin-to-skin contact and exclusive breastfeeding by trained intervention delivery team through home visits. The intervention group mother-infant-dyads were supported to practice ciKMC till day 28 after birth or until the baby wriggled-out. All infants in the intervention and control groups received Home Based Post Natal Care (HBPNC) visits by government health workers. Cognitive, language, motor and socio-emotional outcomes were assessed at infant-ages 6- and 12-months using Bayley Scale of Infant Development (BSID-III). Other outcomes measured were infant temperament, maternal depression, maternal sense of competence, mother-infant bonding and home-environment. We performed post-hoc equivalence testing using two one-sided tests of equivalence (TOST) to provide evidence that ciKMC does not do harm in terms of neurodevelopment.

Results
In the intervention arm, the median (IQR) time to initiate ciKMC was 48 (48 to 72) hours after birth. The mean (SD) duration of skin-to-skin-contact was 27.9 (3.9) days with a mean (SD) of 8.7 (3.5) hours per day. We did not find significant effect of ciKMC on any of the child developmental outcomes during infancy. The TOST analysis demonstrated that composite scores for cognitive, language and motor domains at 12 months among the study arms were statistically equivalent.

Conclusion
Our study was unable to capture any effect of ciKMC on neurodevelopment during infancy in this sample of stable late preterm or term small for gestational age infants. Long term follow-up may provide meaningful insights.

Trial registration
The trial is registered at clinicaltrials.gov NCT02631343 dated February 17, 2016; Retrospectively registered.
The views of physicians and nurses on the potentials of an electronic assessment system for recognizing the needs of patients in palliative care
Authors: Radionova Natalia , Becker Gerhild , Mayer-Steinacker Regine , Gencer Deniz , Rieger Monika A. , Preiser Christine 
Published: April 2020

AbstractObjectivesPatients in oncological and palliative care (PC) often have complex needs, which require a comprehensive treatment approach. The assessment of patient-reported outcomes (PROs) has been shown to improve identification of patient needs and foster adjustment of treatment. This study explores occupational routines, attitudes and expectations of physicians and nurses with regards to a planned electronic assessment system of PROs.MethodsTen physicians and nine nurses from various PC settings in Southern Germany were interviewed. The interviews were analysed with qualitative content analysis.ResultsThe interviewees were sceptical about the quality of data generated through a patient self-assessment system. They criticised the rigidity of the electronic assessment questionnaire, which the interviewees noted may not fit the profile of all palliative patients. They feared the loss of personal contact between medical staff and patients and favoured in-person conversation and on-site observations on site over the potential system. Interviewees saw potential in being able to discover unseen needs from some patients. Interviewees evaluated the system positively in the case that the system served to broadly orient care plans without affecting or reducing the patient-caregiver relationship.ConclusionsA significant portion of the results touch upon the symbolic acceptance of the suggested system, which stands for an increasing standardisation and technisation of medicine where interpersonal contact and the professional expertise are marginalized. The study results can provide insight for processes and communication in the run-up to and during the implementation of electronic assessment systems.
Systemic Inflammation and Outcome in 2295 Patients with Stage I–III Colorectal Cancer from Scotland and Norway: First Results from the ScotScan Colorectal Cancer Group
Authors: Park James H. , Fuglestad Anniken J. , Køstner Anne H. , Oliwa Agata , Graham Janet , Horgan Paul G. , Roxburgh Campbell S. D. , Kersten Christian , McMillan Donald C. 
Published: April 2020

Abstract
Background
Systemic inflammatory response (SIR) is an adverse prognostic marker in colorectal cancer (CRC) patients. The ScotScan Colorectal Cancer Group was established to examine how markers of the SIR differ between populations and may be utilised to guide prognosis.

Patients and Methods
Patients undergoing resection of stage I–III CRC from two prospective datasets in Scotland and Norway were included. The relationship between the modified Glasgow Prognostic Score (mGPS; combination of C-reactive protein and albumin) and overall survival (OS) was examined. The relationship between OS, adjuvant chemotherapy regime and mGPS was examined in patients with stage III colon cancer.

Results
A total of 2295 patients were included. Patients from Scotland were more inflamed despite controlling for associated characteristics using multivariate logistic regression or propensity score matching (OR 2.82, 95% CI 1.98–4.01, p < 0.001). mGPS had similar independent prognostic value in both cohorts (Scotland: HR 1.27, 95% CI 1.12–1.45; Norway: HR 1.23, 95% CI 1.01–1.49) and stratified survival independent of TNM group in the whole cohort. In patients with stage III colon cancer receiving adjuvant therapy, there appeared to be a survival benefit in systemically inflamed patients receiving oxaliplatin but not single-agent 5-fluorouracil or capecitabine.

Conclusions
The SIR differs between populations from different countries; however prognostic value remains similar. The present study strongly supports the routine reporting of the mGPS in patients with CRC.
What's in a title? The developing role of an artist-critic in the university
Authors: Daichendt G. James 
Published: April 2020

AbstractArts professionals within higher education struggle with identity. Dual roles across departments, the changing role of the arts professor and non-traditional positions have challenged the notion of the studio arts instructor and whether institutional expectations are the best way to think about the future of the arts in higher education. As a veteran arts professor, dean, art historian, art critic and artist – my role is not as straightforward as I originally thought it might be as an undergrad studio art major. Through a series of significant streams in my education and personal life, including successes and failures in the academic and professional art world – a new identity emerged that is not represented in search profiles, academic departments or administrative positions.
Bio-equivalence study of two oral doxycycline formulations (doxycycline kela 75%Â® and mebcodox 75%Â®) in broiler Chickens
Authors: El-Komy Ashraf , Aboubakr Mohamed 
Published: April 2020

The present study was designed to assess the comparative bio-equivalence of Doxycycline Kela 75%Â® and Mebcodox 75%Â® in healthy broiler chickens after oral administration of both products in a dose of 20 mg doxycycline base/kg.b.wt. Twenty four broiler chickens were divided into two groups. The first group was designed to study the pharmacokinetics of Doxycycline Kela 75%Â®, while the 2nd group was designed to study the pharmacokinetics of Mebcodox 75%Â®. Each broiler chickens in both groups were orally administered with 20 mg doxycycline base/kg.b.wt. Blood samples were obtained from the wing vein and collected immediately before and at 0.08, 0.16, 0.25, 0.5, 1, 2, 4, 6, 8, 12 and 24 hours after a single oral administration The disposition kinetics of Doxycycline Kela 75%Â® and Mebcodox 75%Â® following oral administration of 20 mg doxycycline base/kg.b.wt. revealed that the maximum blood concentration [Cmax] were 3.35 and 3.28 Î¼g/ml and attained at [tmax] of 0.97 and 0.99 hours, respectively.In conclusion: Mebcodox 75%Â® is bioequivalent to Doxycycline Kela 75%Â® since the ratios of Cmax, AUC0-24 and AUC0-âˆž (T/R) was 0.97, 0.95 and 0.94 respectively. These are within the bioequivalence acceptance range. Mebcodox 75%Â® and Doxycycline Kela 75%Â® are therefore bioequivalent and interchangeable.Â Â Â
Der Wandel von Economic Citizenship im Zuge der europäischen Integration
Authors: Nachtwey Oliver , Seeliger Martin 
Published: April 2020

Zusammenfassung
Die Frage nach dem sozialen Gehalt der europäischen Integration ist nach wie vor ungeklärt. Während auf europäischer Ebene die zivilen und politischen Dimensionen von „Citizenship“ gestärkt wurden, sind gerade hinsichtlich der ökonomischen und sozialen Rechte die Entwicklungen uneindeutig, widersprüchlich – und noch wenig erforscht. Der vorliegende Text überträgt Citizenship als zentrale Kategorie der Modernisierungstheorie auf die Erforschung der europäischen Integration. Ein besonderer Schwerpunkt liegt hierbei auf der Analyse des Wandels von „Economic Citizenship“ als spezielle Kategorie staatsbürgerlicher Rechte mit Blick auf die Bundesrepublik Deutschland. Diese Dynamik diskutieren wir am Beispiel von drei Politikfeldern, die unterschiedliche Ebenen von „Economic Citizenship“ abbilden. Mit diesem Aufsatz verfolgen wir zwei Ziele: Erstens wollen wir Marshalls modernisierungstheoretische These der fortschreitenden sozialen Integration unter den Bedingungen der europäischen Integration überprüfen und zweitens das Konzept der „Economic/Industrial Citizenship“, das zuvor mit wenigen Ausnahmen keine große Rolle in der Weiterentwicklung von Marshalls Theorie gespielt hat, systematisch und empirisch in den Vordergrund stellen.
Alles nur Mode? Organisation und Sprache in den Creative Industries
Authors: Nyfeler Judith , Hasse Raimund 
Published: April 2020

Zusammenfassung
Mit Bezug auf die Modeindustrie und unter Berücksichtigung von zwei empirischen Untersuchungsfällen zeigt dieser Beitrag, wie Kreativität über Routinen, Projekte und Kooperationen sowie durch Sprache – retrospektiv mittels Storytellings und Shows; prospektiv mittels Narrativen – hervorgebracht wird. Kreativität – verstanden als Entwurf, Herstellung und Darstellung eines Produkts, das Kreativitätszuschreibungen ermöglicht – ist somit ein kollektiver Prozess (d. h. sie wird durch eine Vielzahl von Akteuren initiiert und umgesetzt), sie ist organisiert (d. h. die Koordination arbeitsteiliger und zeitlich befristeter Projekte erfolgt über bestimmte Organisationen bzw. Abteilungen oder Stellen), und sie ist institutionell verankert (d. h. durch Werte und Grundüberzeugungen so abgesichert, dass sie erwartet wird). Die abschließende Diskussion erörtert Implikationen insbesondere im Hinblick auf Innovationseffekte und thematisiert Fragen der Übertragbarkeit, die über die Creative Industries hinausreichen.
Nicht-/Anerkennung im Lebenszusammenhang prekär Beschäftigter ohne Paarbeziehung: Kompensation oder Kumulation von Anerkennungsdefiziten?
Authors: Wimbauer Christine , Motakef Mona 
Published: April 2020

Zusammenfassung
Im Zentrum des Beitrages stehen Anerkennungsverhältnisse bei prekär Beschäftigten ohne Paarbeziehungen, die wir aus einer sinnverstehenden Perspektive auf den Lebenszusammenhang untersuchen: Werden erwerbsseitige Anerkennungsdefizite (und fehlende Paar-Liebe) in anderen Nahbeziehungen oder anderen Sinndimensionen kompensiert, abgefedert oder verstärkt? Grundlage ist Honneths Anerkennungstheorie, wonach ein gelungenes Selbstverhältnis – neben rechtlicher Anerkennung – intersubjektiver Anerkennung in der Erwerbssphäre und der Liebessphäre bedarf. Datenbasis sind acht narrative teil-leitfadengestützte Einzelinterviews mit prekär Beschäftigten ohne Paarbeziehung, die wir deutschlandweit zwischen 2014 und 2016 erhoben und hermeneutisch-fallrekonstruktiv ausgewertet haben. Empirisch fundiert werden drei idealtypische Konstellationen nachgezeichnet: Die Abmilderung erwerbsseitiger Anerkennungsdefizite durch Anerkennung in Nahbeziehungen oder alternativen Sinnquellen; ambivalente Relationierungen von Nicht-/Anerkennung in den Anerkennungssphären und die Kumulation multipler Anerkennungsdefizite. Zentral für eine oft verlaufskurvenförmige Kumulation von Anerkennungsdefiziten sind die gesellschaftliche Erwerbsarbeitszentrierung, Paarnormativität, die nicht adäquate Berücksichtigung von Sorgearbeit (Care) sowie von gesundheitlichen Beeinträchtigungen.
Detecting Shared Genetic Architecture Among Multiple Phenotypes by Hierarchical Clustering of Gene-Level Association Statistics
Authors: McGuirl Melissa R , Smith Samuel Pattillo , Sandstede Björn , Ramachandran Sohini 
Published: April 2020

AbstractMcGuirl et al. present a new method, Ward clustering to identify Internal Node branch length outliers using Gene Scores (WINGS), for identifying shared genetic architecture among multiple phenotypes. Past research...Emerging large-scale biobanks pairing genotype data with phenotype data present new opportunities to prioritize shared genetic associations across multiple phenotypes for molecular validation. Past research, by our group and others, has shown gene-level tests of association produce biologically interpretable characterization of the genetic architecture of a given phenotype. Here, we present a new method, Ward clustering to identify Internal Node branch length outliers using Gene Scores (WINGS), for identifying shared genetic architecture among multiple phenotypes. The objective of WINGS is to identify groups of phenotypes, or “clusters,” sharing a core set of genes enriched for mutations in cases. We validate WINGS using extensive simulation studies and then combine gene-level association tests with WINGS to identify shared genetic architecture among 81 case-control and seven quantitative phenotypes in 349,468 European-ancestry individuals from the UK Biobank. We identify eight prioritized phenotype clusters and recover multiple published gene-level associations within prioritized clusters.
PENERAPAN MODEL BRAIN BASED LEARNING (BBL) UNTUK MENINGKATKAN KETERAMPILAN BERPIKIR KRITIS SISWA PADA MATERI USAHA DAUNN ENERGI
Authors: Lestari Utami Pemuji , Malik Adam , Mulhayatiah Diah 
Published: April 2020

According to preliminary results Karya Pembangunan 2 Bandung, the average score test critical thinking skill of students lesson in physics are low, namely 44,80. One of alternatives that can be used in improved the skills of critical thinking students is by applying a Brain Based Learning (BBL). Research aims to understand learning use the model BBL and the increase in critical thinking skill students to the matter effort and energy. Methods used in this research is pre-experimental design, with the design one-group pretest-posttest .The sample is class XI MIA which consisted of 25 people were chosen in using a technique sampling saturated. The results of the study showed the average all meeting activity teachers of 90,27 % and activity students 89,57 % are including the very good. In addition there has been increasing critical thinking skill students on effort matter and energy with a rise of 0,62 of medium category. Thus, Brain Based Learning’s model (BBL) can be used as alternatives in improved the skills of critical thinking of students to the matter effort and energy.
UJI KECEPATAN SESAAT MELALUI GERAK PARABOLA MENGGUNAKAN SOFTWARE TRACKER PADA PERMUKAAN GESEK
Authors: Nurfauzan Muhamad Fasha , Santi Santi , Rahmawati Sarah Nur , Sari Marnita Geptia 
Published: April 2020

Penelitian ini menguji kecepatan sesaat pada sebuah sistem bola tipis berongga yang menggelinding pada bidang lengkung tanpa kecepatan awal. Percobaan dilakukan dengan mengubah kekasaran bidang lintasan lengkung yang dilalui bola. Lintasan pertama memiliki kekasaran yang lebih besar daripada lintasan kedua yang nilai koefien gesek dapat diabaikan. Percobaan ini dilakukan dengan menganalisa titik jatuh bola sebagai sumbu x dan titik pelepasan bola sebagai sumbu y secara analitik dan ekperimental. Secara eksperimen yaitu dilakukan dengan cara melepaskan bola dari puncak bidang lengkung dan menandai titik jatuh bola saat sampai ke dasar. Gerakan bola selama meluncur direkam menggunakan video recorder handphone, lalu dianalisis menggunakan software traker. Pengolahan data dilakukan melalui proses manual menggunakan rumus gerak parabola, hukum kekekalan energi mekanik. Sofware tacker sendiri berfungsi sebagai analisis vidio pada setiap tracket. Selanjutnya menbandingkan nilai kecepatan relatif pada kedua sistem yaitu bidang kasar dan bidang licin. Hasil percobaan menunjukan bahwa.lintasan licin memiliki kecepatan sesaat lebih besar daripada kecepatan sesaat pada lintasan kasar. Dengan nilai secara pehitungan lintasan licin 1,431 m/s dan lintasan kasar 1,323 m/s. Sedangkan dengan menggunakan tracker nilai kecepatan sesaat pada gerak parabola di lintasan licin adalah 1,712 m/s dan di lintasan kasar adalah 1,589 m/s.
MENGANALISIS SUDUT PENDULUM PADA BIDANG MIRING MENGGUNAKAN SOFTWARE TRACKER VIDEO
Authors: Syaepudin Muhammad Rully 
Published: April 2020

Telah dilakukan percobaan untuk menentukan sudut dan frekuensi pada pendulum (m) yang digantungkan pada sisi baki (M) dalam bidang miring. Pendulum yang digunakan adalah beban dengan massa 5 gram. Variasi sudut bidang miring ) mulai dari 30o, 45o, dan 53o, sedangkan variasi panjang tali mulai dari 0,095 m, 0,189 m, dan 0,254 m. Analisis data dilakukan dengan menggunakan software tracker video. Hasil percobaan berdasarkan analisis video tracker menunjukkan besar nilai sudut yang dibentuk bandul terhadap bidang miring dan juga diperoleh besar nilai frekuensi sudut pendulum. Panjang tali yang dibuat berbeda dan besar sudut bidang miring yang di ubah-ubah ternyata mempengaruhi dari besar sudut yang dibentuk oleh pendulum tersebut.
MENENTUKAAN MOMENTUM DAN KOEFISIEN RESTITUSI BENDA TUMBUKAN MENGGUNAKAN TRACKER VIDEO ANALYSE
Authors: Anjani Riska 
Published: April 2020

Peristiwa tumbukan dua bola yang berada pada suatu lintasan merupakan salah satu fenomena fisika yang terjadi dalam waktu yang singkat sehingga untuk mendapatkan data kecepatan bola sebelum dan setelah terjadi tumbukan, diperlukan perangkat yang mampu merekam gejala tersebut dengan ketelitian tinggi. Penelitian ini bertujuan untuk menentukan besar momentum, koefisien restitusi (e) dan jenis tumbukan yang terjadi dari peristiwa tumbukan dua bola yang direkam lalu dianalisis oleh Tracker Video Analysis. Dengan software ini, data hasil tracking mengenai tumbukan direpresentasikan dalam bentuk data dan grafik. Hasil analisis untuk bola bekel melaju menuju bola pasir yang berada dalam keadaan diperoleh e = 0,32475, untuk bola berisi pasir dalam keadaan diam dan kelereng bergerak mendekatinya diperoleh e = 0,189963, dan untuk bola berisi pasir dalam keadaan diam dan bola kosong bergerak mendekatinya diperoleh e = 0,184151. Dengan demikian, dapat disimpulkan bahwa penentuan koefisien resistusi (e) menggunakan Tracker Video Anlyse sesuai dengan kajian teori.