bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desarrollo humano sostenible, post acuerdo de paz y Estado social de derecho: “Balances y estrategias en la era del postconflicto colombiano bajo la mirada de la cooperación internacional”
Authors: Quintana Pérez Bleidis Vanessa 
Published: November 2020

El concepto de Desarrollo Humano Sostenible se encuentra inmerso en la voluntad del Constituyente Colombiano, que establece en el Preámbulo de la Carta Política, al Estado como el principal garante para promover el bienestar de los ciudadanos. No obstante, ¿Por qué los habitantes del territorio colombiano padecen diariamente de inequidad, desigualdad social y falta de acceso a la justicia? Las respuestas planteadas a este interrogante son diversas, pues se atribuyen causas desde distintas perspectivas.
Ante tales realidades, la presente, es una investigación crítica con naturaleza reflexiva, exploratoria y bajo el enfoque cualitativo, que, a partir de una amplitud monográfica permite confrontar la realidad social, política y económica con los factores existenciales del conocimiento del objeto: el Acuerdo de Paz en Colombia. Los resultados arrojados determinan las estrategias que debe realizar el Estado colombiano en materia de Cooperación Internacional bajo los nuevos retos que impone el mencionado acuerdo.
PET-Amyloid After Inconclusive Cerebrospinal Fluid Biomarkers in Clinical Practice. Is it Necessary to Duplicate Procedures?
Authors: Carrera-Muñoz Ismael , Triguero-Cueva Lucía , Romero-Fábrega Juan C. , Triviño-Ibáñez Eva M. , Vilchez-Carrillo Rosa , Carnero-Pardo Cristóbal , Gómez-Río Manuel 
Published: November 2020

Introduction:
In the absence of a gold standard for in vivo Alzheimer disease (AD) diagnosis,
AD biomarkers such as cerebrospinal fluid biomarkers (CSF-B) and PET-Amyloid are considered
diagnostically useful in clinical practice guidelines and have consensual appropriate use criteria (AUC).
However, little evidence has been published on their utilization in the clinical setting or on approaches
to mismatched results. The objective of this work was to evaluate the use of AD biomarkers in clinical
practice, focusing on the implementation of PET-Amyloid in cases of inconclusive CSF-B.

Methods:
This naturalistic, ambispective case series included patients fulfilling AUC for CSF-B and
PET-Amyloid whose CSF-B results were non-diagnostic (target population), analyzing the diagnostic
certainty, the treatment approach, and the relationship between CSF-B and PET-Amyloid results.

Results:
Out of 2373 eligible patients, AD biomarkers were studied in 417 (17.6%), most frequently due
to cognitive impairment in under 65-year-olds, using CSF-B in 311 patients and PET-Amyloid in 150.
CSF-B results were non-diagnostic for 44 patients (52.3% male; aged 60.9±6.6 years), who then underwent
PET-Amyloid study, which was positive in 31. A ‘k’ coefficient of 0.108 was obtained between
CSF-B and PET-amyloid (54.5% concordance). In multivariate regression analysis, Aβ42 was the only
significant predictor (p= 0.018) of a positive PET-Amyloid result. In the target population, PETAmyloid
increased diagnostic confidence by 53.7% (p <0.001) and modified the therapeutic approach in
36.4% of cases.

Conclusion:
These findings support the duplication of AD biomarkers and demonstrate that the implementation
of PET-Amyloid provides an early and certain diagnosis to guide appropriate treatment.
Cerebrospinal Fluid and Blood CX3CL1 as a Potential Biomarker in Early Diagnosis and Prognosis of Dementia
Authors: Kulczyńska-Przybik Agnieszka , Słowik Agnieszka , Mroczko Piotr , Borawski Bartłomiej , Groblewska Magdalena , Borawska Renata , Mroczko Barbara 
Published: November 2020

Background:
A growing body of evidence highlights the crucial role of neuroinflammation
and chemokine involvement in cognitive impairment pathophysiology. Fractalkine (CX3CL1) appears
to be a relevant causative factor in the development of dementia, particularly at the early stages of the
disease. However, limited data are available on the levels of CX3CL1 in the cerebrospinal fluid (CSF)
and blood. Additionally, to date, its utility as a biomarker for MCI or AD has not been studied.

Objective:
The aim of the present study was to evaluate the clinical utility of CX3CL1 in the early diagnosis
of cognitive impairment. We also compared the diagnostic usefulness of CX3CL1 with other biomarkers
associated with neuroinflammation.

Methods:
A total of 60 patients with cognitive impairment, including 42 patients with AD and 18 subjects
with MCI, as well as 20 cognitively healthy controls were enrolled in the study. CSF and blood
concentrations of CX3CL1, CCL-2, and YKL-40 were measured by ELISA.

Results:
Significantly higher CSF and blood concentrations of CX3CL1 were observed in MCI and AD
patients compared to older individuals without cognitive impairment. The increase in the levels of
CX3CL1 and YKL-40 in non-demented subjects was associated with MCI. The area under the ROC
curve for CX3CL1 in MCI subjects was larger in comparison to classical AD markers.

Conclusion:
Presented results indicate a crucial role of CX3CL1 in the pathology of cognitive impairment
and the potential usefulness of this protein in the early diagnosis of MCI and AD.
Penerapan proses pembelajaran di Finlandia pada pembelajaran di Indonesia
Authors: Suciyati Alfi 
Published: November 2020

Finlandia sebagai negara dengan sistem pendidikan terbaik, telah menjadi rujukan bagi pelaksanaan pendidikan negara-negara di dunia. Indonesia sebagai negara yang terus berusaha dalam perbaikan kualitas pendidikan, perlu mempelajari apa saja strategi pendidikan di Finlandia dan memilah-milah mana yang sesuai dengan situasi kondisi di Indonesia dan mana yang tidak. Tujuan penulisan ini untuk mengungkap bagaimana detail pembelajaran di Finlandia dan kemungkinan penerapannya di Indonesia, dengan acuan utama buku karangan Timothy D. Walker yang berjudul Teach Like Finland, 33 Simple Strategies for Joyfull Classrooms. Penelitian ini menggunakan metode studi literatur. Hasil dari penelitian ini yaitu: 1). strategi dari pembelajaran di sekolah Finlandia yang sudah banyak diterapkan di sekolah Indonesia, yaitu; masuk ke alam liar, merekrut tim kesejahteraan, mengejar mimpi kelas, menggunakan buku pegangan, menggunakan teknologi, dan memasukkan musik, 2). strategi dari pembelajaran di sekolah Finlandia yang dapat diterapkan di sekolah Indonesia yaitu; belajar sambil bergerak, recharge sepulang sekolah, mengenal setiap anak, bermain dengan murid, menghapus bullying dengan program tertentu, berkawan, mulai dengan kebebasan, membuat rencana pembelajaran bersama siswa, dan mengajarkan hal-hal mendasar dan, 3). strategi dari pembelajaran di sekolah Finlandia yang sulit diterapkan di sekolah Indonesia yaitu; jadwal istirahat otak.
Studi Eksplorasi Program Edunation dalam Mempersiapkan Fasilitator Belajar di Yayasan Emmanuel
Authors: Ani Yubali , Munthe Ashiong Parhehean , Widiastuti Widiastuti 
Published: November 2020

Program Edunation di Yayasan Emmanuel adalah program yang mempersiapkan fasilitator (pengajar) belajar yang sedang duduk di tingkat SMA agar mampu mengajar siswa sekolah dasar di lingkungan sekitar mereka. Tujuan dari penelitian ini adalah untuk mengeksplorasi: (1) kegiatan yang diperlukan untuk mempersiapkan fasilitator belajar di Yayasan Emmanuel; (2) pelaksanaan program Edunation dalam mempersiapkan fasilitator belajar ini; (3) materi yang diberikan dalam mempersiapkan fasilitator belajar; (4) manfaat yang diperoleh fasilitator belajar, Yayasan Emmanuel, dan siswa yang diajar melalui program ini; dan (5) kendala yang dihadapi dalam melaksanakan program Edunation dalam mempersiapkan fasilitator. Metode yang digunakan adalah penelitian kualitatif deskriptif dengan metode eksplorasi. Subjek penelitan terdiri dari 20 siswa. Waktu penelitian dilaksanakan dari Maret-Juni 2018. Teknik pengumpulan data yang digunakan adalah wawancara dan observasi. Hasil penelitan ini antara lain: 1) Pelatihan, praktek langsung, kunjungan ke tempat mengajar fasilitator, membuat alat peraga, permainan yang bervariasi; 2) dilakukan sebanyak delapan kali sesi selama satu semester; 3) materi yang diberikan adalah pedagogi, konten calistung (membaca, menulis, berhitung), manajemen kelas, dan pengenalan diri; 4) fasilitator belajar menjadi lebih peduli kepada siswa usia sekolah di lingkungan mereka, Yayasan Emmanuel mencapai visi yang diharapkan dari setiap siswa, dan siswa menjadi lebih semangat dalam belajar; 5) kendala yang dihadapi adalah waktu yang terbentur dengan kegiatan sekolah dari salah satu sekolah peserta.
“Como está escrito”: releitura de LXX Isaías 29.14B e LXX Jeremias 9.22-23 em 1 Coríntios 1.18-31
Authors: Adriano Filho José 
Published: November 2020

As citações, alusões e ecos das Escrituras judaicas presentes nas cartas de Paulo não são apenas textos-prova, mas estão conectados com as formas como esses textos e essas tradições foram interpretados no desenvolvimento da história bíblica. Considerando isso, este artigo procura compreender como Paulo interpreta LXX Isaías 29.14b e LXX Jeremias 9.22-23 em 1 Coríntios 1.18-31, citações introduzidas respectivamente por “Como está escrito” (1.19) e “Para que, como está escrito” (1.31). Partindo do desenvolvimento narrativo do texto, o artigo demonstra como a ressignificação desses textos fundamenta o argumento de que Deus tanto destruirá e anulará a sabedoria e inteligência “deste mundo” como assinala uma correlação entre a manifestação da sua sabedoria e poder na cruz de Cristo e a vocação da comunidade cristã.
O Espírito Santo na tradição protestante: perspectivas a partir da teologia reformada
Authors: Caldas Filho Carlos Ribeiro 
Published: November 2020

A teologia cristã tem dedicado muito espaço e atenção para a reflexão a respeito do ser de Deus – teologia propriamente – e da pessoa de Cristo – cristologia. Mas nem sempre tem sido dada atenção ao Espírito Santo, a “pessoa esquecida da Trindade”. O presente artigo apresenta, ainda que apenas em síntese, como a vertente da Reforma Protestante do século XVI, conhecida popular, mas erroneamente, como “calvinista”, elaborou o tema pneumatológico, isto é, a doutrina da pessoa e da obra do Espírito Santo. Para tanto, recorrerá à sua principal fonte primária, a saber, textos de João Calvino, e a dois teólogos reformados contemporâneos, quais sejam, Hendrikus Berkhof e Jürgen Moltmann.
A construção de pequenos espaços de cuidado e gratuidade como resistência às violências: uma relação entre pastoral e teologia da cidadania
Authors: Zeferino Jefferson 
Published: November 2020

Por mei o de um mapeamento das publicações sobre teologia pública no Brasil, nota-se que são recorrentes os textos que conjugam pastoral e teologia da cidadania. Essa relação é desenvolvida como modo de contribuição aos estudos em teologia pública, bem como tentativa de reflexão acerca do problema da violência. Ambienta essa discussão o contexto amplo de violências, o qual desmascara pretensas neutralidades e requer, do fazer teológico, uma aterrissagem atenta, histórica e sensível ao sofrimento humano. A partir da literatura marginal (Carrascoza) e da hermenêutica filosófica de Ricoeur, demonstra--se a contraposição entre cuidado e violência e se dialoga com a noção de pastoral como elemento que pode auxiliar a aprofundar a compreensão do cuidado como uma constante antropológica a ser refletida e cultivada enquanto elemento agregador na construção de pequenos espaços de cuidado e gratuidade.
Do exclusivismo ao inclusivismo: a virada da igreja católica frente à diversidade religiosa
Authors: Ribeiro Antônio Lopes 
Published: November 2020

Uma religião aberta em seu início, jamais impermeável às outras religiões, o cristianismo recrudesceu-se sobre si mesmo ao tornar-se religião oficial do Império Romano. Isto tem um motivo: a fim de unificar politicamente o Império, o imperador romano proibiu qualquer expressão religiosa que não fosse cristã. Assim, o cristianismo tornou-se soberano na Cultura Ocidental, onde foi gestado, posicionando-se como única e verdadeira religião. No cristianismo católico, esse monoculturalismo religioso é simbolizado pelo velho axioma: extra ecclesiam nulla salus. Sob o pretexto de ser depositária exclusiva da fé cristã, a Igreja católica historicamente se afirmou como única via possível de salvação frente às expressões cristãs cisionárias e também frente às religiões não cristãs, defendendo um retorno à barca de Pedro, no âmbito do cristianismo, ou propondo às outras religiões, a formação de uma única civilização cristã, num processo de aglutinação de todas elas, em torno de si. Este artigo trata sobre a virada de página dessa posição da Igreja católica, que se deu no Vaticano II, obrigando-a a se desvencilhar dessa camisa de força à qual estava submetida, saindo de um acentuado exclusivismo para uma experiência de inclusão religiosa, lançando-se positivamente ao encontro com a diversidade e pluralidade religiosa
JESUS BANDIDO: MESSIANISMO POPULAR E BANDITISMO SOCIAL NO PERÍODO NEOTESTAMENTÁRIO BÍBLICO
Authors: Pereira Júnior Basílio Henrique , Hoefelmann Verner 
Published: November 2020

A abordagem do Jesus histórico através de uma ótica sociológica que priorize o diálogo com os movimentos populares no contexto histórico do Novo Testamento é cada vez mais necessária. O contexto histórico-político-social do Messias foi explorado neste artigo por meio dos aspectos antropológicos e epistemológicos. Aprofundou-se sobre a política vigente dos dias narrados no Novo Testamento e encontrou-se uma outra face da sociedade palestina do início do século I d.C. Este artigo reconstruiu o ambiente político-social da palestina judaica neste período e analisou os aspectos do messianismo popular e banditismo social no Novo Testamento. Evidenciou-se nesse trabalho a ligação direta entre o Jesus histórico e a esperança messiânica judaica, tornando-os inseparáveis na compreensão do texto sacro. Este fato mostra um Jesus que não só teve preleções de cunho religioso, mas a personificação de alguém que viveu e falou da realidade social da sua época.
Intersektionalitet – begrebsrejse, kritik og nytænkning
Authors: Christensen Ann-Dorte , Qvotrup Jensen Sune 
Published: November 2020

Gennem de sidste 30 år har intersektionalitetsperspektivet været på en vidtforgrenet rejse på tværs af discipliner og nationale kontekster. Rejsen diskuteres i denne artikel dels på baggrund af forfatternes egen forståelse af intersektionalitet, dels i et perspektiv, som er informeret af den internationale litteratur om rejsende begreber og teorier. Denne litteratur har pointeret. at begrebsrejser ofte medfører produktiv dynamik og nytænkning, men også at begrebsrejser sjældent er konfliktfrie. Således har også den rejse som intersektionalitetsperspektivet har foretaget i høj grad afstedkommet debat og konflikt. Artiklen analyserer den seneste debat og diskuterer aktuelle konfliktpunkter. Dette gælder spørgsmål som, hvorvidt begrebet specifikt angår minoritetskvinder, hvorvidt der i den europæiske reception er sket en uhensigtsmæssig fortrængning af racebegrebet, hvorvidt mænd kan være intersektionelle subjekter, samt hvorvidt begrebet primært omhandler strukturer eller identiteter. Særligt sidstnævnte kan opfattes som en uhensigtsmæssig opposition, der strider imod intersektionalitetsbegrebets princip om at analysere, hvordan sociale differentieringsformer gensidigt former hinanden på tværs af mikro-, meso- og makroniveauer. Denne pointe illustrerer vi ved at vise, hvordan nutidige diskurser om køn, etnicitet og ligestilling på et strukturelt niveau er med til at rammesætte de subjektpositioner, som er til rådighed for etniske minoritetsmænd og dermed forme deres erfaringer på et identitets- og hverdagslivsniveau.
The Impact of Bariatric Surgery on Incident Microvascular Complications in Patients With Type 2 Diabetes: A Matched Controlled Population-Based Retrospective Cohort Study
Authors: Singh Pushpa , Adderley Nicola , Subramanian Anuradhaa , Gokhale Krishna , Singhal Rishi , Toulis Konstantinos A. , Bellary Srikanth , Nirantharakumar Krishnarajah , Tahrani Abd A. 
Published: November 2020

OBJECTIVE
To assess the impact of bariatric surgery (BS) on incident microvascular complications of diabetes-related foot disease (DFD), sight-threatening diabetic retinopathy (STDR), and chronic kidney disease (CKD) in patients with type 2 diabetes and obesity.

RESEARCH DESIGN AND METHODS
A retrospective matched, controlled population-based cohort study was conducted of adults with type 2 diabetes between 1 January 1990 and 31 January 2018 using IQVIA Medical Research Data (IMRD), a database of primary care electronic records. Each patient with type 2 diabetes who subsequently had BS (surgical group) was matched on the index date with up to two patients with type 2 diabetes who did not have BS (nonsurgical group) within the same general practice by age, sex, preindex BMI, and diabetes duration.

RESULTS
Included were 1,126 surgical and 2,219 nonsurgical participants. In the study population 2,261 (68%) were women. Mean (SD) age was 49.87 (9.3) years vs. 50.12 (9.3) years and BMI was 46.76 (7.96) kg/m2 vs. 46.14 (7.49) kg/m2 in the surgical versus nonsurgical group, respectively. In the surgical group, 22.1%, 22.7%, 52.2%, and 1.1% of patients had gastric band, sleeve gastrectomy, Roux-en-Y gastric bypass (RYGB), and duodenal switch, respectively. Over a median follow-up of 3.9 years (interquartile range 1.8–6.4), BS was associated with reduction in incident combined microvascular complications (adjusted hazard ratio 0.53, 95% CI 0.43–0.66, P &lt; 0.001), DFD (0.61, 0.50–0.75, P &lt; 0.001), STDR (0.66, 0.44–1.00, P = 0.048), and CKD (0.63, 0.51–0.78, P &lt; 0.001). Analysis based on the type of surgery showed that all types of surgery were associated with a favorable impact on the incidence of composite microvascular complications, with the greatest reduction for RYGB.

CONCLUSIONS
BS was associated with a significant reduction in incident diabetes-related microvascular complications.
Emotional Regulation and Diabetes Distress in Adults With Type 1 and Type 2 Diabetes
Authors: Coccaro Emil F. , Lazarus Sophie , Joseph Joshua , Wyne Kathline , Drossos Tina , Phillipson Louis , de Groot Mary 
Published: November 2020

OBJECTIVE
To explore the correlates of diabetes-related distress (DD) with psychometrically valid assessments of emotional regulation in individuals with type 1 and type 2 diabetes.

RESEARCH DESIGN AND METHODS
Adults with diabetes (n = 298) were assessed for psychological issues possibly associated with diabetes and were further evaluated with measures of negative emotional experience (ER-Exp) and skill at regulating such experiences (ER-Skill) and measures of DD, perceived psychosocial stress, diabetes literacy, and diabetes self-care.

RESULTS
ER-Exp was directly related to DD, while ER-Skill was inversely related to DD. Together, these ER variables displayed a medium-size relationship (β = 0.45) with DD. Inclusion of variables related to diabetes self-care and perceived psychosocial stress was associated with only an 18% reduction (i.e., β = 0.45 to β = 0.38) in the strength of this relationship, while the magnitude of relationships between DD and perceived psychosocial stress (β = 0.15) and diabetes self-care (β = −0.09) was relatively small.

CONCLUSIONS
These data suggest that DD is meaningfully linked with negative emotionality, and skill at regulating such emotions, in adults with diabetes. This relationship appears to be stronger than that between DD and perceived psychological stress or diabetes self-care. If so, DD (and possibly A1C) may be improved in those with diabetes and difficulties with negative emotionality.
Impact through Engagement
Authors: Nelson Elizabeth , Burns Frances 
Published: November 2020

BackgroundThe Administrative Data Research Centre Northern Ireland (ADRC NI) is a research partnership between Queen’s University Belfast and Ulster University to facilitate access to linked administrative data for research purposes for public benefit and for evidence-based policy development. This requires a social licence extended by publics which is maintained by a robust approach to engagement and involvement.
ApproachPublic engagement is central to the ADRC NI’s approach to research. Research impact is pursued and secured through robust engagement and co-production of research with publics and key stakeholders. This is done by focusing on data subjects (the cohort of people whose lives make up the datasets, placing value on experts by experience outside of academic knowledge, and working with public(s) as key data advocates, through project steering committees and targeted events with stakeholders. The work is led by a dedicated Public Engagement, Communications and Impact Manager.
DiscussionWhile there are strengths and weaknesses to the ADRC NI approach, examples of successful partnerships and clear pathways to impact demonstrate its utility and ability to amplify the positive impact of administrative data research. Working with publics as data use becomes more ubiquitous in a post-COVID-19 world will become more critical. ADRC NI’s model is a potential way forward.
Forecasting of Catfish Sales by Time Series Using the SARIMA method
Authors: Woro Tri Handayani Nandia Rani , Maslim Martinus , Mudjihartono Paulus 
Published: November 2020

Abstrak. Sistem informasi yang mengotomatiskan proses bisnis, terutama dengan persyaratan khusus masih relevan saat ini. Clarias Makmur, sebuah usaha mikro di Indonesia yang membiakkan dan menjual ikan lele menggunakan sistem informasi ini untuk menjalankan penjualan, pengeluaran, modal, dan pelaporan mereka. Penjualan ikan lele sebagai makhluk hidup memiliki ciri khas tersendiri yang menunjukkan pola musiman yang unik. Sebuah model bernama SARIMA (Seasonal Autoregressive Integrated Moving Average) kemudian diusulkan untuk memprediksi penjualan. Lebih lanjut, sistem yang disebut SITRAN dibuat online supaya perusahaan mikro ini beroperasi secara fleksibel. Ada 400 data penjualan yang digunakan dalam metode ini untuk membuat model dan prediksi, sedangkan 100 data lainnya digunakan untuk menguji akurasi metode. Hasil penelitian menunjukkan bahwa SARIMAX (21,2,0) (1,0,0,12) adalah model terbaik yang ditemukan dalam percobaan dan yang memberikan RMSE terkecil. Kata kunci: prediksi; penjualan ikan lele; pola musiman; SARIMA Abstract. An information system that automates a business process, especially with specific requirement is still relevant these days. Clarias Makmur, a micro cooperation in Indonesia that breeds and sells catfish uses such an information system to carry out their sales, expenses, capital and reporting. The sales of catfish as a living creature have their own characteristics showing the unique seasonal pattern. A model named SARIMA (Seasonal Autoregressive Integrated Moving Average) is then proposed to predict the sales. Furthermore the system called SITRAN is made to be online for the cooperation to operate flexibly. There are 400 sales data used for the method to model and predict, while another 100 are used to test the method accuracy. The result shows that SARIMAX(21,2,0)(1,0,0,12) is the best model found in the experiment giving the smallest RMSE. Keywords: prediction; catfish sales; seasonal pattern; SARIMA