bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hydrogel Adhesion by Wrinkling Films
Authors: Kato Masatoshi , Asoh Taka‐Aki , Uyama Hiroshi 
Published: October 2019

AbstractA novel adhesion control method for hydrogels utilizing swelling‐induced wrinkling gel films is developed. Structures such as flat, crease, and wrinkle at the interface of adhered gels are controlled by swelling ratio of gel films. The role of microstructures at the gel–gel interface is investigated by adhesive strength measurement. Aligned wrinkles are fabricated with anisotropic swelling films. The adhesive strength of hydrogels with wrinkles parallel to tensile direction is larger than that with perpendicular wrinkles. Adhered gels detach without damage to their surfaces when the wrinkle structures are disrupted by peeling of the wrinkled film. Moreover, thermoresponsive film is used to control wrinkle structures at the adhered interface by temperature. The adhered interface is stable in cold water because of the existence of wrinkles; however, they detach in hot water due to wrinkle deformation. By using wrinkle structure at adhesive interfaces, both strong adhesion and easy detachment of hydrogels are achieved.
Evidence From Parkinson's Disease That the Superior Colliculus Couples Action and Perception
Authors: Pretegiani Elena , Vanegas‐Arroyave Nora , FitzGibbon Edmond J. , Hallett Mark , Optican Lance M. 
Published: October 2019

AbstractBackgroundAction and perception should be coordinated for good visual‐motor performance. The mechanism coupling action and perception may be a prominence map in the intermediate layer of the superior colliculus that modulates motor and attentional/perceptual processes. This coordination comes with a cost: the misperception that briefly overlapping stimuli are separated in time. Our model predicts that abnormal intermediate layer of the superior colliculus inhibition, such as that arising from increased basal ganglia output, would affect the action and perception coupling, and it would worsen the misperception.ObjectiveTo test the prominence map model by measuring reaction times and perceptions in human intermediate layer of the superior colliculus dysfunction.MethodsWe measured the saccadic and perceptual reaction time changes and the percept for different temporal asynchronies between fixation point offset and peripheral target onset in Parkinson's disease (PD).ResultsWe found that increased basal ganglia inhibitory output to the intermediate layer of the superior colliculus prominence map disrupted the normal coupling of action and perception. With increasing temporal asynchronies, the PD perceptual reaction times increased approximately 3 times more than the increase of the saccadic reaction times. Also, PD subjects misperceive small overlaps as gaps for temporal asynchronies up to 3 times longer than controls. The results can be reproduced by an intermediate layer of the superior colliculus rostral‐caudal gradient of inhibition.ConclusionThese findings support the hypothesis that a prominence map in the intermediate layer of the superior colliculus couples action and perception through modulation of attention. A dysfunction of this network quantifies abnormal basal ganglia output and could underlie visual deficits, including common, yet poorly understood, misperceptions and visual‐motor deficits of PD. © 2019 International Parkinson and Movement Disorder Society
Sector‐wise golden‐angle phase contrast with high temporal resolution for evaluation of left ventricular diastolic dysfunction
Authors: Fyrdahl Alexander , Ramos Joao G. , Eriksson Maria J. , Caidahl Kenneth , Ugander Martin , Sigfridsson Andreas 
Published: October 2019

PurposeTo develop a high temporal resolution phase‐contrast pulse sequence for evaluation of diastolic filling patterns, and to evaluate it in comparison to transthoracic echocardiography.MethodsA phase‐contrast velocity‐encoded gradient‐echo pulse sequence was implemented with a sector‐wise golden‐angle radial ordering. Acquisitions were optimized for myocardial tissue (TE/TR: 4.4/6.8 ms, flip angle: 8º, velocity encoding: 30 cm/s) and transmitral flow (TE/TR: 4.0/6.6 ms, flip angle: 20º, velocity encoding: 150 cm/s). Shared velocity encoding was combined with a sliding‐window reconstruction that enabled up to 250 frames per cardiac cycle. Transmitral and myocardial velocities were measured in 35 patients. Echocardiographic velocities were obtained with pulsed‐wave Doppler using standard methods.ResultsMyocardial velocity showed a low difference and good correlation between MRI and Doppler (mean ± 95% limits of agreement 0.9 ± 3.7 cm/s, R2 = 0.63). Transmitral velocity was underestimated by MRI (P < .05) with a difference of −11 ± 28 cm/s (R2 = 0.45). The early‐to‐late ratio correlated well (R2 = 0.66) with a minimal difference (0.03 ± 0.6). Analysis of interobserver and intra‐observer variability showed excellent agreement for all measurements.ConclusionsThe proposed method enables the acquisition of phase‐contrast images during a single breath‐hold with a sufficiently high temporal resolution to match transthoracic echocardiography, which opens the possibility for many clinically relevant variables to be assessed by MRI.
An Assessment Model for a Standard Gill Net Incorporating Direct and Indirect Selectivity Applied to Walleye
Authors: Radomski Paul , Anderson Charles S. , Bruesewitz Richard E. , Carlson Andrew J. , Borkholder Brian D. 
Published: October 2019

Abstract
Fisheries managers regularly use catch-per-effort (CPE) statistics and length-frequency distributions from standard gill-net surveys to inform future management activities. The data from these surveys is implicitly tied to the net's selectivity, and caution should be used when not accounting for selectivity. We combined indirect and direct methods for estimating the parameters of absolute selectivity by using data from Minnesota's standard gill-net surveys for Walleye Sander vitreus, enabling the estimation of density from CPE. The indirect piece used a state-wide gill-net database and generalized linear modeling to identify a set of possible shapes for the selectivity curves. The direct piece added information based on 94 mark–recapture experiments that were paired with standard gill-net surveys. The resulting statistical assessment model used a bi-lognormal-shaped selectivity curve that was geometrically similar for each mesh, and it estimated fishing intensity that differed substantially with mesh size. Applications of the selectivity model allow the estimation of Walleye density as CPE divided by absolute selectivity by length-bin. The estimated absolute selectivity for the Minnesota standard gill net increased with increasing Walleye length to a peak of 0.76 ha/net at 535 mm and then decreased to about 0.26 at about 800 mm (1.0 and 0.34 relative selectivities, respectively). Fishing intensity increased with mesh size, so the selectivity curves for the individual meshes and that for the standard gill net (5 meshes in series) differed substantially from the curves that have resulted from indirect selectivity models that have ignored size-dependent encounter probabilities and assumed equal contact probabilities for all meshes. We caution investigators that adjusting gill-net catch data with indirect selectivity models that assume equal contact probabilities for each mesh may introduce considerable bias to estimates of population abundance and length distributions.
Promoting self‐efficacy in patients with chronic disease beyond traditional education: A literature review
Authors: Farley Holly 
Published: October 2019

AbstractAimTo examine barriers to self‐efficacy and strategies beyond traditional education that promote self‐efficacy for patients living with chronic disease. The review questions were as follows: (a) What are barriers to self‐efficacy in patients experiencing chronic disease? and (b) What non‐traditional strategies and programmes can be implemented by healthcare leaders to promote self‐efficacy in patients with chronic disease?DesignIntegrative review.MethodData sources searched were CINAHL, Google Scholar, Health Source, Academic Search Complete and PsycARTICLES published between January 2014–January 2018. Synthesis and thematic analyses were conducted on 24 articles.ResultsThree themes were identified as barriers to self‐efficacy: health literacy, access and support. Four prominent strategies were found to promote self‐efficacy: self‐management programmes, telehealth, mobile applications, gaming and social media. The findings indicate self‐efficacy for patients with chronic conditions can improve with new interventions. Enhancing traditional education and boosting self‐efficacy could increase treatment adherence and decrease cost.
Forensic dental identification of remains in five prefectures in the Kansai region of Japan
Authors: Ichioka Hiroaki , Bando Risa , Tsuboi Hajime , Idota Nozomi , Kumagai Wataru , Ikegaya Hiroshi 
Published: October 2019

AbstractThe numbers of forensic dental analyses and police dentists performing the analyses differ among the prefectures in Japan. Very little is known about the numbers of these analyses and the processes used to enlist dental experts. This report investigated the method of assigning police dentists for identification of the remains, number of the dentists, number of assigned dental analyses, payment for dental services, etc in five prefectures in the Kansai region. The number of studied remains, dental analyses, and identification by the dental experts annually processed by prefectural police stations in 2015, 2016, and 2017 are summarized. The number of the dental analyses in the five prefectures in the Kansai region ranged from 0.3 to 2.3 per 100 recovered remains, which is considered low. There was no relationship between the number of the dental analyses performed and the number of the police dentists. Utilizing the results from this report enables the creation of a database to establish better systems for forensic dentistry, which will enable a larger number of the dental analyses and earlier and accurate identification of unidentified remains.
Synthesis of novel unsaturated polyester/g‐C3N4‐CeO2 composites with enhanced fire safety properties
Authors: Huang Yufeng , Dong Xuan , Li Yufeng 
Published: October 2019

AbstractIn this article, the flame‐retardant materials and flame‐retardant system as a reference for flame retardant unsaturated polyester (UP) have been provided. To date, with the help of some layered nano‐materials, the electrical, mechanical, thermal stability, and fire‐retardant properties of a large number of composite materials can be significantly improved. Here, the graphite phase carbon nitride (g‐C3N4) combined with cerium oxide (CeO2) have been successfully synthesized and as a filling material into UP, could improve flame‐retardant performance. The structure and morphology of the composites were confirmed by X‐ray powder diffraction and transmission electron microscopy, at the same time, the effect of Van der Waals' force in the reunite and stacking of the UP were also studied by scanning electron microscope. Moreover, the combustion performance test of composites through thermogravimetry analysis and microscale combustion calorimeter, the preparation of flame retardancy groups, the functionalization of materials, which revealed that the synthesized flame‐retardant materials had better performance. The results have indicated that the peak heat release rate of flame‐retardant materials reduced 33.6% than pure UP. After adding preciously little layered nanomaterial, the flame retardancy of composites is better than before, which is a novel route to improve fire safety.
Reliability and Minimal Detectable Change in the Gait Assessment and Intervention Tool in Patients With Multiple Sclerosis
Authors: Gor‐García‐Fogeda María D. , Tomé‐Redondo Silvia , Simón‐Hidalgo Cristina , Daly Janis J. , Molina‐Rueda Francisco , Cano‐de‐la‐Cuerda Roberto 
Published: October 2019

BackgroundGait impairment is one of the main causes of disability in people with multiple sclerosis. The Gait Assessment and Intervention Tool is an observational gait scale that assesses kinematic parameters using video recordings.ObjectiveTo study intra‐ and interrater reliability and the minimal detectable change of the Gait Assessment and Intervention Tool in individuals with multiple sclerosis.DesignObservational study.SettingMultiple Sclerosis Foundation.ParticipantsThirty‐five participants with multiple sclerosis were assessed (12 men, 23 women; 47.7 ± 11 y; Expanded Disability Status Scale = 4.32 ± 1.4).InterventionsNot applicable.Main Outcome MeasurementsIntra‐ and interrater reliability of the Gait Assessment and Intervention Tool was assessed for each limb using the Intraclass Correlation Coefficient. In addition, the minimal detectable change was calculated.ResultsThe Intraclass Correlation Coefficient for the intrarater reliability was found to be excellent for the total score both for the right side (.91; 95% confidence interval 95% CI .85‐.95) and the left side (.93; 95% CI .88‐.96). The intraclass correlation coefficient for the interrater reliability was .91 (95% CI .85‐.95) for the right side, and .93 (95% CI .88‐.96) for the left side. The minimal detectable change for the intrarater reliability was 1.19 points for the right side and .77 for the left side.ConclusionsThe Gait Assessment and Intervention Tool exhibits excellent intra‐ and interrater reliability and a small minimal detectable change for people with multiple sclerosis.
Supramolecules‐Guided Synthesis of Brightly Near‐Infrared Au22 Nanoclusters with Aggregation‐Induced Emission for Bioimaging
Authors: Wei Yifei , Luan Weiling , Gao Feng , Hou Xinyu 
Published: October 2019

AbstractProtein‐protected gold nanoclusters with emission in the near‐infrared wavelength range have been widely considered for applications in biomedical fields. However, their quantum yield (QY) remains low, thus limiting their practical applications. Herein, a novel strategy to synthesize bovine serum albumin–encapsulated gold nanoclusters (BSA‐AuNCs) with QY of 23% is developed. Assembled coordination polymers (supramolecules) of Au(I)‐BSA complexes are initially formed because of the intermolecular forces between BSA ligands. The forces are easily controlled by pH level during the reaction, leading to significant change in the photoluminescence of BSA‐AuNCs. By regulating the pH and reaction temperature, Au(0)@Au(I) core‐shell structured BSA‐AuNCs are fabricated in 2 h. Importantly, such AuNCs are in a rigidified state with high Au(I) content in the shell, offering an explanation for their high luminescence character. Further increasing QY to 29% is achieved by confining BSA‐AuNCs into a cationic polymer, poly(allylamine) hydrochloride (AuNCs@PAH). Enhanced cellular uptake and improved sensitivity of AuNCs@PAH to glutathione compared to BSA‐AuNCs is demonstrated. These findings may give insights into the synergistic effect of pH level and reaction temperature on the properties of protein‐encapsulated AuNCs and provide a possible way for up‐scaled fabrication of brighter AuNCs protected by other protein templates.
Stress analysis due to internal explosion pressure of designed flameproof enclosure for hazardous area
Authors: Ahirwal Bhagirath , Prasad Rashmi , Kashyap Sudhir Kumar , Banerjee Gautam 
Published: October 2019

AbstractFlameproof (Ex d) enclosures are constructed in such a way that an internal ignition of a flammable atmosphere will not be transmitted outside the enclosure and thereby preventing the ignition of surrounding flammables. The large Ex d enclosure was designed for gas group IIB explosive atmosphere with the help of MATLAB and ANSYS software and further a study of stress analysis due to internal pressure had been carried out on the plates and cover by keeping the thickness of body plate and cover constant. The study showed that stress was observed more in the center of the plate and reducing toward the edges of plates. The value of the length and breadth ratio (a/b) was found out with the help of the curve fitting method to calculate maximum stress (σmax) in the designed Ex d enclosure. The calculated maximum stress of all the plates was less than the simulated results, so the simulated results indicated that the designed enclosure is within the safety limit and suitable for hazardous area.
In vitro hepatotoxicity of Petasites hybridus extract (Ze 339) depends on the concentration, the cytochrome activity of the cell system, and the species used
Authors: Forsch Kristina , Schöning Verena , Assmann Greta Marie , Moser Christin , Siewert Beate , Butterweck Veronika , Drewe Jürgen 
Published: October 2019

AbstractZe 339, a CO2 extract prepared from the leaves of Petasites hybridus, possesses antispasmodic and anti‐inflammatory effects and is proven to be effective in the treatment of allergic rhinitis. To study possible hepatotoxic effects of Ze 339, its main constituents and metabolites, a series of in vitro investigations were performed. Furthermore, different reconstituted fractions of extract (petasins and fatty acid fraction) were examined in three in vitro test systems using hepatocytes: Two human cell lines, with lower and higher activity of cytochrome P450 enzymes (HepG2, HepaRG) as well as a rodent cell line with high cytochrome P450 activity (H‐4‐II‐E), were used. Metabolic activity, assessed by the WST‐1 assay, was chosen as indicator of cytotoxicity. To assess potential bioactivation of Ze 339 compounds, metabolic experiments using S9 fractions from rats, dogs, and humans and isolated cytochromes (human/rat) were performed, and the formation of reactive metabolites was assessed by measuring cellular concentrations of glutathione and glutathione disulphide.Our data revealed that the cytotoxicity of Ze 339, its single constituents, and main metabolites depends on the concentration, the cytochrome activity of the cell system, and the species used.
Visible‐Light‐Driven p–n Type BiMSbO6(M=Ti, Sn)/BiOBr Heterojunction Photocatalyst toward Degradation of Levofloxacin
Authors: Huang Panqi , Shen Yue , Luan Jingfei 
Published: October 2019

AbstractA new visible light‐driven p‐n type BiMSbO6(M=Ti, Sn)/BiOBr heterojunction photocatalyst was prepared in this paper. The XRD results showed that pure BiTiSbO6 and pure BiSnSbO6 crystallized well with the pyrochlore‐type structure, stable cubic crystal system by space group Fd3 m and the XPS results further confirmed its high crystallinity. The crystal parameters of pure BiSnSbO6 and pure BiTiSbO6 were 10.23459 Å and 9.87708 Å, respectively. After visible light irradiation for 100 minutes, the removal rate of levofloxacin with 5 wt%, 10 wt% or 20 wt% BiMSbO6(M=Ti, Sn)/BiOBr heterojunction photocatalyst could all reach more than 85%, which was far higher than that with pure BiSnSbO6 (4.79%) as a photocatalyst or that with pure BiTiSbO6 (5.35%) as a photocatalyst. In addition, the form of p‐n heterojunction improved the reusability of pure BiOBr. After four cycles of photodegradation experiments for levofloxacin, the removal rate of levofloxacin with 20 wt% BiTiSbO6/BiOBr heterojunction photocatalyst or 10 wt% BiSnSbO6/BiOBr heterojunction photocatalyst decreased by 11.48% or 11.02%. However, the removal rate of levofloxacin with pure BiOBr decreased by 18.68%. Moreover, h+ contributed the most during the degradation procedure of levofloxacin with BiMSbO6(M=Ti, Sn)/BiOBr heterojunction photocatalyst. Eventually, working mechanism of BiMSbO6(M=Ti, Sn)/BiOBr heterojunction photocatalyst was described in detail.
Combinatorial Immunophenotyping of Cell Populations with an Electronic Antibody Microarray
Authors: Liu Ruxiu , Chu Chia‐Heng , Wang Ningquan , Ozkaya‐Ahmadov Tevhide , Civelekoglu Ozgun , Lee Dohwan , Arifuzzman A K M , Sarioglu A. Fatih 
Published: October 2019

AbstractImmunophenotyping is widely used to characterize cell populations in basic research and to diagnose diseases from surface biomarkers in the clinic. This process usually requires complex instruments such as flow cytometers or fluorescence microscopes, which are typically housed in centralized laboratories. Microfluidics are combined with an integrated electrical sensor network to create an antibody microarray for label‐free cell immunophenotyping against multiple antigens. The device works by fractionating the sample via capturing target subpopulations in an array of microfluidic chambers functionalized against different antigens and by electrically quantifying the cell capture statistics through a network of code‐multiplexed electrical sensors. Through a combinatorial arrangement of antibody sequences along different microfluidic paths, the device can measure the prevalence of different cell subpopulations in a sample from computational analysis of the electrical output signal. The device performance is characterized by analyzing heterogeneous samples of mixed tumor cell populations and then the technique is applied to determine leukocyte subpopulations in blood samples and the results are validated against complete blood cell count and flow cytometry results. Label‐free immunophenotyping of cell populations against multiple targets on a disposable electronic chip presents opportunities in global health and telemedicine applications for cell‐based diagnostics and health monitoring.
srcDiff: A syntactic differencing approach to improve the understandability of deltas
Authors: Decker Michael John , Collard Michael L. , Volkert L. Gwenn , Maletic Jonathan I. 
Published: October 2019

AbstractAn efficient and scalable rule‐based syntactic differencing approach is presented. The tool srcDiff is built upon the srcML infrastructure. srcML adds abstract syntactic information into the code via an XML format. A syntactic difference of srcML documents is then taken. During this process, the differences are further refined using a set of rules that model typical editing patterns of source code by developers. Thus, the resulting deltas model edits that are programmer centric versus a purely syntactic tree edit view. Other syntactic differencing approaches focus on obtaining an optimal tree edit distance with the assumption that this will produce an accurate difference. While this may work well for small or simple changes, the differences quickly become unreadable for more complex changes. By contrast, the approach presented here purposely deviates from an optimal tree edit difference in order to create a delta that is both easier to understand and better models changes between the original and modified. To evaluate the approach, a comparison user study against a state‐of‐the‐art syntactic differencing approach and two line‐based differencing tools is conducted as an online within‐participant study with about 70 subjects on 14 sample changes. The results provide support that the rule‐based syntactic differencing produces more accurate and understandable deltas.
Gene Editing to Generate Versatile Human Pluripotent Stem Cell Reporter Lines for Analysis of Differentiation and Lineage Tracing
Authors: Bao Xiaoping , Adil Maroof M. , Muckom Riya , Zimmermann Joshua A. , Tran Aurelie , Suhy Natalie , Xu Yibo , Sampayo Rocío G. , Clark Douglas S. , Schaffer David V. 
Published: October 2019

Abstract
Transcription factors (TFs) are potent proteins that control gene expression and can thereby drive cell fate decisions. Fluorescent reporters have been broadly knocked into endogenous TF loci to investigate the biological roles of these factors; however, the sensitivity of such analyses in human pluripotent stem cells (hPSCs) is often compromised by low TF expression levels and/or reporter silencing. Complementarily, we report an inducible and quantitative reporter platform based on the Cre-LoxP recombination system that enables robust, quantifiable, and continuous monitoring of live hPSCs and their progeny to investigate the roles of TFs during human development and disease. Stem Cells 2019;37:1556–1566