bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of adherence to physical cancer rehabilitation guidelines among cancer patients and cancer centers: a cross-sectional observational study
Authors: IJsbrandy Charlotte , Ottevanger Petronella B. , Gerritsen Winald R. , van Harten Wim H. , Hermens Rosella P. M. G. 
Published: September 2020

Abstract
Purpose
To tailor implementation strategies that maximize adherence to physical cancer rehabilitation (PCR) guidelines, greater knowledge concerning determinants of adherence to those guidelines is needed. To this end, we assessed the determinants of adherence to PCR guidelines in the patient and cancer center.

Methods
We investigated adherence variation of PCR guideline-based indicators regarding [1] screening with the Distress Thermometer (DT), [2] information provision concerning physical activity (PA) and physical cancer rehabilitation programs (PCRPs), [3] advice to take part in PA and PCRPs, [4] referral to PCRPs, [5] participation in PCRPs, and [6] PA uptake (PAU) in nine cancer centers. Furthermore, we assessed patient and cancer center characteristics as possible determinants of adherence. Regression analyses were used to determine associations between guideline adherence and patient and cancer center characteristics. In these analyses, we assumed the patient (level 1) nested within the cancer center (level 2).

Results
Nine hundred and ninety-nine patients diagnosed with cancer between January 2014 and June 2015 were included. Of the 999 patients included in the study, 468 (47%) received screening with the DT and 427 (44%) received information provision concerning PA and PCRPs. Subsequently, 550 (56%) patients were advised to take part in PA and PCRPs, which resulted in 174 (18%) official referrals. Ultimately, 280 (29%) patients participated in PCRPs, and 446 (45%) started PAU. Screening with the DT was significantly associated with information provision concerning PA and PCRPs (OR 1.99, 95% CI 1.47–2.71), advice to take part in PA and PCRPs (OR 1.79, 95% CI 1.31–2.45), referral to PCRPs (OR 1.81, 95% CI 1.18–2.78), participation in PCRPs (OR 2.04, 95% CI 1.43–2.91), and PAU (OR 1.69, 95% CI 1.25–2.29). Younger age, male gender, breast cancer as the tumor type, ≥2 cancer treatments, post-cancer treatment weight gain/loss, employment, and fatigue were determinants of guideline adherence. Less variation in scores of the indicators between the different cancer centers was found. This variation between centers was too low to detect any association between center characteristics with the indicators.

Conclusions
The implementation of PCR guidelines is in need of improvement. We found determinants at the patient level associated with guideline-based PCR care.

Implications for Cancer Survivors
Implementation strategies that deal with the determinants of adherence to PCR guidelines might improve the implementation of PCR guidelines and the quality of life of cancer survivors.
The CRADLE teaching methodology: developing foreign language and entrepreneurial skills in primary school pupils
Authors: Weicht Rebecca , Ivanova Irina , Gikopoulou Ourania 
Published: September 2020

AbstractIn recent years, a consensus has grown across the European Union that the acquisition of transversal skills—including foreign language and entrepreneurial skills—is key to the success of learners in their personal and professional life. The CRADLE teaching methodology for primary school teachers is the first teaching methodology to simultaneously foster both of these skill sets, employing a cross-curricular, activity-based, pupil-centred, exploratory teaching and learning approach based on a linear four-step process inspired by Design Thinking with problem-solving and designing solutions in mind. This article discusses the implementation of the CRADLE teaching methodology in six primary schools in three European countries. Based on an analysis of project plans, lesson observations and teachers’ feedback during the pilot stage of the methodology, we are able to demonstrate that the methodology is a flexible tool for developing students’ knowledge and skills. The observed results provide evidence of increased pupil interest and involvement, successful acquisition of foreign language and communication skills (accuracy and fluency in speaking, vocabulary development, ability to express opinions and ideas, answer questions and understand instructions) and emerging entrepreneurial skills such as self-efficacy, creativity, valuing ideas, taking initiatives, planning and management, and working with others.
Recommandations sur la prise en charge du cancer du pénis
Authors: Grobet-Jeandin Elisabeth 
Published: September 2020

RésuméLe cancer du pénis est une pathologie relativement rare dans nos régions qui est souvent associée à une infection à HPV. Il se manifeste par une lésion de la verge, distale dans la majorité des cas. L’examen clinique local est essentiel pour réaliser le staging local, déterminant pour le bilan pré-opératoire. Le statut ganglionnaire inguinal doit également être systématique, étant donné que l’atteinte ganglionnaire est le facteur pronostic principal de la maladie.Le traitement du cancer du pénis étant essentiellement chirurgical, il convient d’adresser tout patient présentant une lésion suspecte de tumeur de la verge à un urologue, pour que ce dernier réalise une biopsie avant d’envisager le traitement. Par la suite, la chirurgie sera le plus conservatrice possible. L’obtention de marges de résections négatives est impérative. Il existe plusieurs techniques de curage ganglionnaire (curage inguinal modifié, lymphadénectomie inguinale totale) qui sont appliquées selon le risque et le stade TNM (tumor, node, metastasis).Le suivi post-opératoire est essentiellement clinique et comprend l’auto-examination régulière de la verge ainsi que des ganglions inguinaux, en association avec des visites médicales régulières jusqu’à cinq ans post-opératoires.
Peridynamic Higher-Order Beam Formulation
Authors: Yang Zhenghao , Oterkus Erkan , Oterkus Selda 
Published: September 2020

AbstractIn this study, a novel higher-order peridynamic beam formulation is presented. The formulation is obtained by using Euler-Lagrange equations and Taylor’s expansion. To demonstrate the capability of the presented approach, several different beam configurations are considered including simply supported beam subjected to distributed loading, simply supported beam with concentrated load, clamped-clamped beam subjected to distributed loading, cantilever beam subjected to a point load at its free end and cantilever beam subjected to a moment at its free end. Transverse displacement results along the beam obtained from peridynamics and finite element method are compared with each other and very good agreement is obtained between the two approaches.
Feedstock choice, pyrolysis temperature and type influence biochar characteristics: a comprehensive meta-data analysis review
Authors: Ippolito James A. , Cui Liqiang , Kammann Claudia , Wrage-Mönnig Nicole , Estavillo Jose M. , Fuertes-Mendizabal Teresa , Cayuela Maria Luz , Sigua Gilbert , Novak Jeff , Spokas Kurt , Borchard Nils 
Published: September 2020

AbstractVarious studies have established that feedstock choice, pyrolysis temperature, and pyrolysis type influence final biochar physicochemical characteristics. However, overarching analyses of pre-biochar creation choices and correlations to biochar characteristics are severely lacking. Thus, the objective of this work was to help researchers, biochar-stakeholders, and practitioners make more well-informed choices in terms of how these three major parameters influence the final biochar product. Utilizing approximately 5400 peer-reviewed journal articles and over 50,800 individual data points, herein we elucidate the selections that influence final biochar physical and chemical properties, total nutrient content, and perhaps more importantly tools one can use to predict biochar’s nutrient availability. Based on the large dataset collected, it appears that pyrolysis type (fast or slow) plays a minor role in biochar physico- (inorganic) chemical characteristics; few differences were evident between production styles. Pyrolysis temperature, however, affects biochar’s longevity, with pyrolysis temperatures > 500 °C generally leading to longer-term (i.e., > 1000 years) half-lives. Greater pyrolysis temperatures also led to biochars containing greater overall C and specific surface area (SSA), which could promote soil physico-chemical improvements. However, based on the collected data, it appears that feedstock selection has the largest influence on biochar properties. Specific surface area is greatest in wood-based biochars, which in combination with pyrolysis temperature could likely promote greater changes in soil physical characteristics over other feedstock-based biochars. Crop- and other grass-based biochars appear to have cation exchange capacities greater than other biochars, which in combination with pyrolysis temperature could potentially lead to longer-term changes in soil nutrient retention. The collected data also suggest that one can reasonably predict the availability of various biochar nutrients (e.g., N, P, K, Ca, Mg, Fe, and Cu) based on feedstock choice and total nutrient content. Results can be used to create designer biochars to help solve environmental issues and supply a variety of plant-available nutrients for crop growth.
Bindung und Reinheit
Authors: Streck Bernhard 
Published: September 2020

ZusammenfassungIm kanonischen Verständnis der Ethnologie ist Religion eine Unterkategorie der Kultur. In der globalistischen Perspektive auf Panmixie lösen sich beide Begriffe auf. Gleichsam als vorsichtige Rechtfertigung der zugegebenermaßen unpräzisen KategorienReligionundKulturmöchte ich ihren gemeinsamen Grund beleuchten, der zwischen Disziplinierung und Lebenshilfe verortet werden kann. Rückbindung an ein Urgeschehen vereint alle Religionen, das Streben nach Reinheit alle Kulturen. Wie dort das Wissen und Erinnern durch Ritus und Mythos am Leben erhalten werden muss, beharren Kulturen ungeachtet ihres synthetischen Aufbaus auf Alter und Authentizität. Die unverzichtbare, d. h. für ein Zusammenleben notwendige Gemeinsamkeit beider Sinnsetzungen liegt in der Disziplinierungsleistung. Religion wie Kultur schaffen Verbindlichkeit, reduzieren Unsicherheit im zwischenmenschlichen Verkehr, sanktionieren Abweichungen und erlauben, ja erzwingen Abgrenzungen gegen Unglauben oder Fremdheit – Qualitäten, die die einmal gestiftete Vertrauenslandschaft bedrohen.
On the specification property and synchronization of uniqueq-expansions
Authors: BARRERA RAFAEL ALCARAZ 
Published: September 2020

AbstractGiven a positive integerMand$q \in (1, M+1]$we consider expansions in baseqfor real numbers$x \in [0, {M}/{q-1}]$over the alphabet$\{0, \ldots , M\}$. In particular, we study some dynamical properties of the natural occurring subshift$(\boldsymbol{{V}}_q, \sigma )$related to unique expansions in such baseq. We characterize the set of$q \in \mathcal {V} \subset (1,M+1]$such that$(\boldsymbol{{V}}_q, \sigma )$has the specification property and the set of$q \in \mathcal {V}$such that$(\boldsymbol{{V}}_q, \sigma )$is a synchronized subshift. Such properties are studied by analysing the combinatorial and dynamical properties of the quasi-greedy expansion ofq. We also calculate the size of such classes as subsets of$\mathcal {V}$giving similar results to those shown by Blanchard [ 10 ] and Schmeling in [ 36 ] in the context of$\beta $-transformations.
Size distribution of Pacific cod (Gadus macrocephalus) in the North Pacific Ocean over 6 millennia
Authors: West Catherine F. , Etnier Michael A. , Barbeaux Steven , Partlow Megan A. , Orlov Alexei M. 
Published: September 2020

AbstractIn this paper, we compile estimates of cod size distributions based on zooarchaeological data and contemporary length-frequency data to look at variability in size composition through time across the North Pacific, from the northern Kuril Islands through the Aleutian Islands to southeast Alaska. The results suggest that a strong longitudinal trend in cod size has remained consistent over time, with the largest cod found to the west. We find that five of nine sites show that overall cod length and distribution of the largest fish remain relatively unchanged. Two sites where we find truncation of the length distributions—or loss of the largest fish—are places where the modern fisheries have the longest history and have been most intense, suggesting a potential for anthropogenic impacts on these local populations. We acknowledge two limitations in these data: (1) there are differences in selectivity between the ancient and modern fisheries; and (2) seasonal variability in fish availability was observed to be an important explanatory variable in the modern data set, but the season of harvest is poorly understood for the ancient collections. Therefore, while differences observed between the two data sets suggest possible anthropogenic influence on the size structure of Pacific cod, they are not conclusive.
Factors associated with adherence to a Mediterranean diet in adolescents from La Rioja (Spain)
Authors: Jiménez Boraita Raúl , Arriscado Alsina Daniel , Gargallo Ibort Esther , Dalmau Torres Josep María 
Published: September 2020

AbstractThe aim of the present study was to describe Mediterranean diet (MD) adherence within a population of adolescents and to analyse the association of multiple factors with adherence. This included a consideration of diverse physical and mental health indicators. The present study was conducted with a representative sample of 761 adolescents (14·51 (sd 1·63) years) from twenty-five educational centres in a northern region of Spain. MD adherence was evaluated, alongside their health-related quality of life, self-esteem, body image satisfaction, BMI, physical activity (PA) level, maximum oxygen consumption, hours of nightly sleep, socio-demographic factors and academic performance. Of the adolescent population, 49 % reported high MD adherence. Being female and having higher levels of PA were found to be predictive factors of adherence to the MD. In addition, maximum oxygen consumption, the presence of environments favourable towards PA engagement and higher self-esteem were also predictive in females, whilst better academic performance and more nightly sleep were additional predictors in males. The associations found between the MD and other health indicators and habits highlight the need to develop promotion strategies from an inter-disciplinary and transversal standpoint.
A randomized controlled trial of cognitive remediation and long-acting injectable risperidone after a first episode of schizophrenia: improving cognition and work/school functioning
Authors: Nuechterlein Keith H. , Ventura Joseph , Subotnik Kenneth L. , Gretchen-Doorly Denise , Turner Luana R. , Casaus Laurie R. , Luo John , Boucher Michael L. , Hayata Jacqueline N. , Bell Morris D. , Medalia Alice 
Published: September 2020

AbstractBackgroundCognitive deficits at the first episode of schizophrenia are predictive of functional outcome. Interventions that improve cognitive functioning early in schizophrenia are critical if we hope to prevent or limit long-term disability in this disorder.MethodsWe completed a 12-month randomized controlled trial of cognitive remediation and of long-acting injectable (LAI) risperidone with 60 patients with a recent first episode of schizophrenia. Cognitive remediation involved programs focused on basic cognitive processes as well as more complex, life-like situations. Healthy behavior training of equal treatment time was the comparison group for cognitive remediation, while oral risperidone was the comparator for LAI risperidone in a 2 × 2 design. All patients were provided supported employment/education to encourage return to work or school.ResultsBoth antipsychotic medication adherence and cognitive remediation contributed to cognitive improvement. Cognitive remediation was superior to healthy behavior training in the LAI medication condition but not the oral medication condition. Cognitive remediation was also superior when medication adherence and protocol completion were covaried. Both LAI antipsychotic medication and cognitive remediation led to significantly greater improvement in work/school functioning. Effect sizes were larger than in most prior studies of first-episode patients. In addition, cognitive improvement was significantly correlated with work/school functional improvement.ConclusionsThese results indicate that consistent antipsychotic medication adherence and cognitive remediation can significantly improve core cognitive deficits in the initial period of schizophrenia. When combined with supported employment/education, cognitive remediation and LAI antipsychotic medication show separate significant impact on improving work/school functioning.
Factors related to follicular oxidative stress in intracytoplasmic sperm injection cycles and its effects on granulosa cells
Authors: Karabulut Seda , Korkmaz Oya , Kutlu Pelin , Keskin Ilknur 
Published: September 2020

SummaryThe aim of the present study was to investigate several common conditions that may potentially be correlated with follicular oxidative status during an intracytoplasmic sperm injection (ICSI) cycle and that include the serum oestrogen level on the day of oocyte pick-up, maternal age and pregnancy outcome. Patients that were enrolled in the study were classified randomly into three groups using their numerical order. The first group were classified based on maternal age (<35 and ≥35 years) (n = 398), the second group on the serum oestradiol (E2) level on the day of human chorionic gonadotropin (hCG) administration (levels >90th percentile and ≤ 90th percentile) (n = 491) and the third group on pregnancy outcome (positive/negative) (n = 376). The groups were matched for the other variables (stimulation protocol, dose of gonadotropin, duration of stimulation, antral follicle count, body mass index, basal follicle stimulating hormone (FSH), and E2 levels and day of hCG trigger) to prevent the possible contribution of those parameters to the results. Each group was matched for other variables (stimulation protocol, dose of gonadotrophin, duration of stimulation, antral follicle count, body mass index, basal FSH and E2 levels and day of hCG trigger) that may have affected the outcome, except for the parameter under investigation. Maternal age (P = 0.044,168 r = 0.418), oestrogen level on day of hCG administration (P = 0.001, r = 0.436) and pregnancy outcome (AUC = 0.65, P = 0.071) were found to be correlated with follicular oxidative status. The results obtained will help us to shield patients from possible situations that may cause oxidative stress and therefore adverse outcomes of an ICSI cycle.
Rapid progression of mitral valve disease in a child with Noonan syndrome
Authors: Doctor Pezad N. , Lawrence David K. , Misra Amrit 
Published: September 2020

AbstractNoonan syndrome is the second most common genetic syndrome associated with congenital heart disease after Trisomy 21. The two most common cardiac lesions associated with Noonan syndrome are pulmonary stenosis and hypertrophic cardiomyopathy. Although the incidence of mitral valve disease in Noonan syndrome ranges between 2 and 6%, rapid progression of mitral valve dysplasia causing severe mitral valve regurgitation and left atrial dilatation is seldom seen. Most cases of mitral valve disease have been diagnosed either on routine echocardiographic surveillance or when presented with heart failure symptoms. We describe an 18-month-old boy with Noonan syndrome presenting in atrial flutter due to a massively enlarged left atrium caused by severe mitral valve regurgitation which developed and progressed in less than 17 months.
Audiovisual Consults by Paramedics to Reduce Hospital Transport After Low-Urgency Calls: Randomized Controlled Trial
Authors: Sykora Roman , Renza Metodej , Ruzicka Jiri , Bakurova Petra , Kukacka Milos , Smetana Jiri , Duska Frantisek 
Published: September 2020

AbstractIntroduction:The effect and subjective perception of audiovisual consults (AVCs) by paramedics with a distant physician in prehospital emergency care (PHEC) remain unexplained, especially in low-urgency calls.Objectives:The primary objective of the study was to evaluate the effect of AVCs by paramedics with a base physician on the rate of patients treated on site without the need of hospital transfer. The co-primary safety outcome was the frequency of repeated ambulance trips within 48 hours to the same patient. Secondary objective was the qualitative analysis of perception of the AVCs.Methods:During a six-week period, the dispatching center of Karlovy Vary Emergency Medical Service (EMS) randomized low-urgency events from a rural area (n = 791) to receive either a mandatory phone-call consult (PHONE), AVC (VIDEO), or performed by the paramedic crew in a routine manner, when phone-call consultation is for paramedic crew optional (CONTROL). Secondarily, the qualitative analysis of subjective perception of AVCs compared to consultation over the phone by the paramedic and consulting physician was performed.Results:Per-protocol analysis (PPA) was performed (CONTROL, n = 258; PHONE, n = 193; and VIDEO, n = 192) in addition to the intention-to-treat (ITT) analysis. Patients (PPA) in both mandatory consulted groups were twice as likely to be treated and left on site compared to the CONTROL (PHONE: OR = 2.07; 95% CI, 1.19 to 3.58; P = 0.01 or VIDEO: OR = 2.01; 95% CI, 1.15 to 3.49; P = .01). Repeated trips to patients treated and left on site in 48 hours occurred in three (8.6%) of 35 cases in the PHONE group and in eight (23.5%) of 34 cases in the VIDEO group.Conclusions:The AVCs of the emergency physician by paramedics was not superior to the mandatory conventional phone call in increasing the proportion of patients treated and left at home after a low-urgency call. The AVC improved the subjective feelings of safety by physicians, but not the satisfaction of patients or paramedics, and may lead to an increased need of repeated trips.
Submesoscale Kinematic Properties in Summer and Winter Surface Flows in the Northern Gulf of Mexico
Authors: Berta M. , Griffa A. , Haza A. C. , Horstmann J. , Huntley H. S. , Ibrahim R. , Lund B. , Özgökmen T. M. , Poje A. C. 
Published: September 2020

AbstractStatistical properties of near‐surface horizontal velocity gradients are obtained from four drifter experiments conducted in the Gulf of Mexico during Summer 2012 and Winter 2016. The data density provided by the near‐simultaneous deployments of 90‐326 surface drifters in each allows direct, drifter‐based estimates of the scale dependence of velocity gradients at separation scales ranging from 200 m to 5 km. The robustness of these estimates, derived from uniquley sampled, nearly equilateral triplets, is confirmed by comparisons with estimates produced from larger drifter clusters, and with estimates based on concurrent Eulerian X‐band radar observations. The winter launches were deployed above a ∼80 m deep mixed layer, one in a region with nearly homogeneous horizontal density structure, the other in a region of strong surface density gradients associated with filaments of fresh Mississippi River water. The summer launches occurred in a shallow (10m) mixed layer, one launched across a mesoscale frontal jet separating regions of horizontally homogeneous density and the other, similar to the corresponding winter launch, also in a region filamented by shallow lenses of cold, fresh water. Seasonal differences are observed, with larger velocity fluctuations and greater variance in divergence and vorticity, especially at the smallest scales, in winter. Differences between same‐season launches are, however, as large as seasonal differences. In both seasons, observations sampling regions directly impacted by fresh water fluxes show strongly skewed vorticity distributions, with cyclonic vorticity dominating strain. For the other launches, one in each season, strain dominated minimally skewed vorticity.