bluuebunny/crossref_metadata_2025_split huggingface dataset:
Shear stress-induced pathological changes in endothelial cells occur through Piezo1 activation of TRPV4
Authors: Swain Sandip M. , Liddle Rodger A. 
Published: July 2020

AbstractAlthough the ion channels Piezo1 and TRPV4 have been implicated in high venous pressure- and fluid shear stress-induced vascular hyperpermeability, they have been described as working independently. Moreover, the mechanism by which Piezo1 and TRPV4 channels in endothelial cells execute the same function is poorly understood. Here we demonstrate that Piezo1 regulates TRPV4 channel activation in endothelial cells and that Piezo1-mediated TRPV4 channel opening is a function of the strength and duration of fluid shear stress. Application of the Piezo1 antagonist, GsMTx4, completely blocked the elevation in intracellular calcium ([Ca2+]i) induced by both fluid shear stress and the Piezo1 agonist, Yoda1. High and prolonged shear stress caused sustained [Ca2+]ielevation which required TRPV4 opening and was responsible for fluid shear stress- and Piezo1-mediated disruption of adherens junctions and actin remodeling. We found that Piezo1’s effects were mediated by phospholipase A2 activation. Blockade of TRPV4 channels with the selective TRPV4 blocker, HC067047, prevented the loss of endothelial cell integrity and actin disruption induced by Yoda1 or shear stress and prevented Piezo1-induced monocyte adhesion to endothelial cell monolayers. These findings demonstrate that Piezo1 activation by fluid shear stress initiates a calcium signal that causes TRPV4 opening which in turn is responsible for the sustained phase calcium elevation that triggers pathological events in endothelial cells.
Generation of an X-ray nanobeam of a free-electron laser using reflective optics with speckle interferometry
Authors: Inoue Takato , Matsuyama Satoshi , Yamada Jumpei , Nakamura Nami , Osaka Taito , Inoue Ichiro , Inubushi Yuichi , Tono Kensuke , Yumoto Hirokatsu , Koyama Takahisa , Ohashi Haruhiko , Yabashi Makina , Ishikawa Tetsuya , Yamauchi Kazuto 
Published: July 2020

Ultimate focusing of an X-ray free-electron laser (XFEL) enables the generation of ultrahigh-intensity X-ray pulses. Although sub-10 nm focusing has already been achieved using synchrotron light sources, the sub-10 nm focusing of XFEL beams remains difficult mainly because the insufficient stability of the light source hinders the evaluation of a focused beam profile. This problem is specifically disadvantageous for the Kirkpatrick–Baez (KB) mirror focusing system, in which a slight misalignment of ∼300 nrad can degrade the focused beam. In this work, an X-ray nanobeam of a free-electron laser was generated using reflective KB focusing optics combined with speckle interferometry. The speckle profiles generated by 2 nm platinum particles were systematically investigated on a single-shot basis by changing the alignment of the multilayer KB mirror system installed at the SPring-8 Angstrom Compact Free-Electron Laser, in combination with computer simulations. It was verified that the KB mirror alignments were optimized with the required accuracy, and a focused vertical beam of 5.8 nm (±1.2 nm) was achieved after optimization. The speckle interferometry reported in this study is expected to be an effective tool for optimizing the alignment of nano-focusing systems and for generating an unprecedented intensity of up to 1022 W cm−2 using XFEL sources.
Private governance responsibilisation in global supply chains: the case of Rana Plaza
Authors: Siddiqui Javed , McPhail Kenneth , Rahman Sharmin Shabnam 
Published: July 2020

PurposeThe paper explores the emergence of private sector responsibilisation for tackling governance issues in a global supply chain. The infamous case of the Rana Plaza collapse in Bangladesh is used to investigate the ways a frameshift, triggered by a manmade disaster, can potentially influence the effectiveness of the certification process in a research site characterised by the presence of a strong state-business nexus.Design/methodology/approachThe empirical work for this paper is based 24 semi-structured interviews with owners, managers, operators, independent inspectors in the ready-made garments (RMG) industry in Bangladesh between 2014 and 2018. We also analyse a range of archival materials. For the purpose of data analysis, we adopted an exploratory flexible pattern matching design with nested template analysis (Sinkovics et al., 2019).FindingsOur analysis suggests that the magnitude of the Rana Plaza collapse triggered several frameshifts in multinational corporations approach towards labour governance in Bangladesh. Subsequently, a responsibility framework for the private sector was created, resulting in significant improvements in working conditions in the sector. However, the sustainability of the labour governance mechanisms was significantly affected by the state's ability to play the role of catalyst in the process, mainly due to the presence of a significant state-business nexus.Originality/valueWe find that broadening the scope of sustainability accounting and assurance process can allow social auditors to play a more meaningful role in triggering collective actions to address labour governance issues in supply chains. However, in a context defined by the presence of a state-business nexus, the sustainability of such a process largely depends on the willingness of the state to play the role of a catalyst.
Intellectual heritages of post-1990 public sector accounting research: an exploration
Authors: Bruns Hans-Jürgen , Christensen Mark , Pilkington Alan 
Published: July 2020

PurposeThe article's aim is to refine prospects for theorising in public sector accounting (PSA) research in order to capture the methodological benefits promised by its multi-disciplinarity.Design/methodology/approachThe study primarily employs a bibliometric analysis of research outputs invoking New Public Management (NPM). Applying a content analysis to Hood (1991), as the most cited NPM source, bibliographic methods and citation/co-citation analysis for the period 1991 to 2018 are mobilised to identify the disciplinary evolution of the NPM knowledge base from a structural and longitudinal perspective.FindingsThe analysis exhibits disciplinary branching of NPM over time and its imprints on post-1990 PSA research. Given the discourse about origins of NPM-based accounting research, there are research domains behind the obvious that indicate disciplinary fragmentations. For instance, novelty of PSA research is found in public value accounting, continuity is evidenced by transcending contextual antecedents. Interestingly, these domains are loosely coupled. Exploring the role of disciplinary imprints designates prospects for post-NPM PSA research that acknowledges multi-disciplinarity and branching in order to deploy insularity as a building block for its inquiries.Research limitations/implicationsCriteria for assessing the limitations and credibility of an explorative inquiry are used, especially on how the proposal to develop cumulative knowledge from post-1990 PSA research can be further developed.Practical implicationsA matrix suggesting a method of ordering disciplinary references enables positioning of research inquiries within PSA research.Originality/valueBy extending common taxonomies of PSA intellectual heritages, the study proposes the ‘inquiry-heritage’ matrix as a typology that displays patterns of theorisation for positioning an inquiry within PSA disciplinary groundings.
The impact of an audit committee's independence and competence on investment decision: a study in Bahrain
Authors: Al-Hadrami Abdullah , Rafiki Ahmad , Sarea Adel 
Published: July 2020

PurposeThis study aims to investigate the impact of the audit committee's (AC) independence and competence on the company's investment decision-making in Bahraini-listed companies.Design/methodology/approachA quantitative method is used, and crosssectional data are collected through a self-administered questionnaire survey. A stratified random sample technique is adopted with a total of 409 respondents from 39 listed companies. A descriptive analysis is used to identify the characteristics of the respondents, while the correlation analysis and linear regression analyses are used to test the model and explain the relationship between variables.FindingsIt is found that the AC independence and AC competence have a positive and significant influence on investment decision-making.Originality/valueThe AC’s independence and competence are importantly crucial for the decision-makers in improving the quality of financial reporting, internal control and audit. This may lead to the increase in investors' trust on financial reports and thereby making favorable investment decisions.
How to measure food loss and waste? A material flow analysis application
Authors: Amicarelli Vera , Bux Christian , Lagioia Giovanni 
Published: July 2020

PurposeThe purpose of this paper is to measure food loss and waste by material flow analysis (MFA) tool. Applying this methodology, the authors estimate wastage-related losses and discuss opportunities for more circular and sustainable practices in the Italian potato industry.Design/methodology/approachMFA is applied to two specific typologies as follows: ready-to-eat (chips) and dried potato products produced in Italy. The analysis refers to the year 2017 as the complete dataset useful for this study includes measurements until this year. A bottom-up and top-down mixed approach is applied, and functional unit refers to 1tof potatoes consumed as final product.FindingsMFA is applied to quantify and qualify material balance associated with 1tof potatoes consumed as final product. In Italy, in 2017, more than 22,000tof fresh tubers were lost, including 3,500–4,800tof starch, equivalent to 52,800–72,600 GJs. Moreover, fewer than 23,000tof skins and scraps were produced within industrial plants, not available for food but suitable for animal feed (dry skins are an excellent carbohydrates source in cattle and poultry feed), starch industry and bioenergy production (biogas and/or bioethanol).Originality/valueThis research is one of the few studies proposing MFA methodology as a tool to measure food waste. This analysis shows its utility in terms of food waste quality/quantity evaluation, supporting both company management and policymakers.
Towards a process model of emotional sensemaking in post-merger integration: linking cognitive and affective dimensions
Authors: Schlindwein Eva , Geppert Mike 
Published: July 2020

PurposeThe purpose of this paper is to advance micro-level theorising of sociocultural post-merger integration (PMI) by merging insights from international business and management research on the cognitive and affective dimensions of PMI.Design/methodology/approachThe paper follows a narrative approach to review the previously separate literatures on cognition and emotion in PMI situations. It draws on insights from management research beyond the PMI context to integrate these literatures and as a result, develops a process model of emotional sensemaking in PMI.FindingsAn emotional sensemaking approach to PMI helps to explain when and why events might or might not motivate individuals to revisit their interpretation of a PMI and illustrates how and why similar PMI events can lead to opposite individual reactions and, thus, obtain heterogeneous integration outcomes.Research limitations/implicationsThe paper discusses how an emotional sensemaking approach can be applied to sociocultural PMI and points to new directions for future studies based on this application. As the model concentrates on the individual level, theoretical implications for sociocultural PMI at the meso- and macro-levels remain limited.Originality/valueThis paper brings forward the dynamics that underlie the processes and outcomes of individuals’ behaviour and reactions to PMI events. The proposed process model of emotional sensemaking in PMI responds to recent calls by sociocultural PMI scholars to promote a processual rather than event-based view of PMI, with a focus on individual actors and an emphasis on the multifaceted dynamics and outcomes of PMI.
Placemakingas an approach of sustainable urban facilities management
Authors: Vukmirovic Milena , Gavrilović Suzana 
Published: July 2020

PurposeThis paper aims to present the potential ofplacemakingas an approach of sustainable urban facilities management and its impacts on the improvement of the planning procedures which was aimed at involving citizens in the process itself. The study is based on the general concept ofplacemakingrepresented as an “overarching idea and a hands-on approach for improving a neighbourhood, city or region”, that serves as a process that “inspires people to collectively reimagine and reinvent public spaces as the heart of every community” (PPS, 2007).Design/methodology/approachThe study used placemaking (onsite analysis, stakeholder identification, citizen survey and emotional mapping) and public participation geographic information systems (The Kernel Density tool in ArcGIS and hot spot analysis) methodologies to map problems and preferences identified by stakeholders related to particular spaces within the move formed by Maršala Birjuzova and Sremska streets in Belgrade. The research covered two-day stakeholders’ workshops including four groups of users participated in the workshop – pupils of local private high school, street residents, students of the Faculty of Forestry and the Faculty of Architecture and owners of local shops and businesses.FindingsResearch has shown that different stakeholders can offer very rational observations on the quality of a particular space and provide clear suggestions on its improvement and transformation. These proposals can be organised in the form of visions of the future appearance and functioning of the space, thus recognising the potential in the function of a sustainable urban facilities management tool in the form of creating a common idea, which will result in the creation of a common space.Research limitations/implicationsThe research covered only part of the process that resulted in the creation of an idea of future public space transformation. Continued research should be conducted after the intervention, which would give a more comprehensive picture of the effects of the approach.Practical implicationsPractical implications include the presentation of the ways different groups of users perceive the actual and future transformation of the street to make this place more user-friendly and sustainable, i.e. practical example of the co-design process.Originality/valueThis paper provide an overview of the possibilities ofplacemakingapproach seen from the perspective of sustainable urban facilities management.
Dufour and Soret effects on Al2O3-water nanofluid flow over a moving thin needle: Tiwari and Das model
Authors: Waini Iskandar , Ishak Anuar , Pop Ioan 
Published: July 2020

Purpose
This paper aims to examine the effect of Dufour and Soret diffusions on Al2O3-water nanofluid flow over a moving thin needle by using the Tiwari and Das model.

Design/methodology/approach
The governing equations are reduced to the similarity equations using similarity transformations. The resulting equations are programmed in Matlab software through the bvp4c solver to obtain their solutions. The features of the skin friction, heat transfer and mass transfer coefficients, as well as the velocity, temperature and concentration profiles for different values of the physical parameters, are analysed and discussed.

Findings
The non-uniqueness of the solutions is observed for a certain range of the physical parameters. The authors also notice that the bifurcation of the solutions occurs in which the needle moves toward the origin (λ < 0). It is discovered that the first branch solutions of the skin friction coefficient and the heat transfer coefficients increase, but the mass transfer coefficient decreases in the presence of nanoparticle. Additionally, the simultaneous effect of Dufour and Soret diffusions tends to enhance the heat transfer coefficient; however, dual behaviours are observed for the mass transfer coefficient. Further analysis shows that between the two solutions, only one of them is stable and thus physically reliable in the long run.

Originality/value
The problem of Al2O3-water nanofluid flow over a moving thin needle with Dufour and Soret effects are the important originality of the present study. Besides, the temporal stability of the dual solutions is examined for time.
Non-similar solution of Sisko nanofluid flow with variable thermal conductivity: a finite difference approach
Authors: Bisht Ankita , Sharma Rajesh 
Published: July 2020

Purpose
The main purpose of this study is to present a non-similar analysis of two-dimensional boundary layer flow of non-Newtonian nanofluid over a vertical stretching sheet with variable thermal conductivity. The Sisko fluid model is used for non-Newtonian fluid with an exponent (n* > 1), that is, shear thickening fluid. Buongiorno model for nanofluid accounting Brownian diffusion and thermophoresis effects is used to model the governing differential equations.

Design/methodology/approach
The governing boundary layer equations are converted into nondimensional coupled nonlinear partial differential equations using appropriate transformations. The resultant differential equations are solved numerically using implicit finite difference scheme in association with the quasilinearization technique.

Findings
This analysis shows that the temperature raises for thermal conductivity parameter and velocity ratio parameter while decreases for the thermal buoyancy parameter. The thermophoresis and Brownian diffusion parameter that characterizes the nanofluid flow enhances the temperature and reduces the heat transfer rate. Skin friction drag can be effectively reduced by proper control of the values of thermal buoyancy and velocity ratio parameter.

Practical implications
The wall heating and cooling investigation result in the analysis of the control parameters that are related to the designing and manufacturing of thermal systems for cooling applications and energy harvesting. These control parameters have practical significance in the designing of heat exchangers and solar thermal collectors, in glass and polymer industries, in the extrusion of plastic sheets, the process of cooling of the metallic plate, etc.

Originality/value
To the best of authors’ knowledge, it is found from the literature survey that no similar work has been published which investigates the non-similar solution of Sisko nanofluid with variable thermal conductivity using finite difference method and quasilinearization technique.
A Kano model, AHP and TOPSIS based approach for selecting the best mobile phone under a fuzzy environment
Authors: Singh Rohit , Avikal Shwetank , Rashmi Rashmi , Ram Mangey 
Published: July 2020

PurposeIn today's era of a digital world, mobile phones have now become an essential part in everyday life. The selection of the best mobile phone among the available alternatives is a complex decision making it a problem for the customers. Mobile phone manufactures are facing a lot of problems for launching/introducing a mobile phone according to the requirement of customers and it depends on a number of criteria/attributes such as: technical specifications, price, brand etc.Design/methodology/approachIn the presented work, the above-discussed problem has been considered as a Multi-Criteria Decision Making MCDM problem and an approach based on Kano model with Fuzzy AHP and TOPSIS has been proposed to solve the problem. The Kano model has been used for identifying the different Kano categories of all the features through a customer survey. Fuzzy AHP has been applied to achieve the weights of each feature in order to introduce a best mobile phone for the customers. TOPSIS has been used for ranking of alternatives.Findingsmain features with different other sub-features have been selected for the study. Different features have been considered as categories and their Kano categories have been found out. The importance of these features has also been calculated by Fuzzy-AHP in terms of their evaluated weights. Different mobile phones have been ranked by TOPSIS according to their features calculated by Fuzzy-AHP. The proposed approach seems effective for identifying/classifying different attributes/features of mobile phones according to customer's requirements.Originality/valueHere, different features of a mobile phone have been considered for designing a suitable mobile phone. Thus, this work can help a designer to design and select a suitable feature for a customer-oriented mobile phone.
Simulation of eutectic plates in medium refrigerated transport
Authors: Radebe Thandiwe Bongani , Huan Zhongjie , Baloyi Jeffrey 
Published: July 2020

Purpose
South Africa is the highest consumer of commercial energy per capita in Africa, ranking 16th in the world for primary energy consumption. It is also ranked among the bottom 50 of the 150 countries regarding energy efficiency. The cold chain is a large contributor through refrigerated transport vehicles. To comply with the changing climate regulations, cryogenic and eutectic systems are systems with great potential for small distance refrigerated transport. The purpose of this paper is to introduce eutectic system to medium distance refrigerated transport.

Design/methodology/approach
This study presents the potential use of Eutectic plates inside a medium refrigerated transport vehicle, by numerically investigating the characteristics of phase change material eutectic plates applied at low-temperature ranges. A physical model and a mathematical model for three-dimensional transient natural flow were developed as proposed by Xiaofeng and Zhang. Using the governing equation of mass, momentum and energy conservation, three Eutectic plate configurations were modeled and simulated in ANSYS Fluent for 5 h.

Findings
A uniform heat transfer and airflow condition inside a refrigerated compartment were predicted using the Reynolds stress model. The configuration with eutectic plates placed at the top and side showed great potential for the system functioning in the South African climate.

Research limitations/implications
Medium refrigerated transport vehicle.

Originality/value
This configuration had a high-temperature distribution across the compartment and promoted high air circulations, showing that it could be ideal for medium refrigerated transport vehicles delivering perishable foodstuffs or non-food goods.