bluuebunny/crossref_metadata_2025_split huggingface dataset:
The development of a Thurstone scale for identifying teacher ability in using information and communication technology
Authors: Arfandi A , Purnamawati  , Nurfaedah  
Published: February 2020

Abstract
Teachers in Indonesia should not only mastery the four competencies (pedagogy, professional, personality, and social). They also must be able to use information technology in the learning process especially in the 4.0 industrial revolution. An instrument to measure the capability of the teacher in using information technology was developed. This article uses the Thurstone Scale as a methodological basis for identifying what capabilities are approved by experts in measuring the ability of teachers in use information and communication technology (ICT) in the learning process in vocational high schools. There are 30 (thirty) statements has analysed, 26 items were Valid in 0.01 significant level, and 4 items were Valid in 0.05 significant level. The instrument developed has good characteristics and all of the statement items meet the valid category with a very good level of reliability. Therefore, all instrument has met the validity and reliability criteria, the instrument will use to measure the ability of teacher in using information and communication technology.
Virtual reality teaching material - virtual reality game with education
Authors: Peng L , Yen Y , Siswanto I 
Published: February 2020

Abstract
This study aims to explore the combination of virtual reality and school education, Recent years, Virtual Reality (VR) is a popular issue. The basic concept of virtual reality is to use an immersive device to isolate. Isolate the user from the real world. compare the situation of virtual reality education and traditional education to students’ learning, and explore whether virtual reality is suitable for use and promotion in schools. Can people generally accept digital technology to replace traditional education, use the convenience brought by virtual reality education and the growth of students.
Development of cooperative learning based electric circuit kit trainer for basic electrical and electronics practice
Authors: Hamid M A , Permata E , Aribowo D , Darmawan I A , Nurtanto M , Laraswati S 
Published: February 2020

Abstract
This study aims to develop an electric circuit trainer kit learning media, study the feasibility of trainer kit learning media, study the feasibility of worksheets for electric circuit learning media, and determine the effectiveness of electric circuit learning media. This study refers to the ADDIE model (Analyze, Design, Development, Implementation, Evaluation). The results showed that the learning media feasibility of the electric Circuit trainer kit-based cooperative learning was included in the category very decent with an average score of 102. Job sheet Media learning is in a very decent category, with an average score of 93.5. Electric circuit trainer-based Cooperative learning is rated very useful for basic electrical and electronics practice with an average n-gain score of 0.77.
Constructive learning through experiments utilization of pandan leaf fiber as a strengthening of composite material
Authors: Johan A B , Ratnawati D , Purnomo S 
Published: February 2020

Abstract
This research was aimed at examining constructivist learning through experiments examining the feasibility of pandan leaf fibers as reinforcement of composite materials. The method used in the study was an experiment, namely conducting an experimental activity of the tensile strength of pandan leaf fibers compared to glass fiber, to obtain new knowledge as an alternative material for reinforcing composite materials. In this case, the pandan leaves studied were taken from the Kepuharjo area of Cangkringan Sleman DIY. Data analysis techniques used were qualitative descriptive, and quantitative descriptive. The results of this research indicated that; (1) constructivist methods were feasible as alternative paradigms for learning science and technology built through the Input-Process-Output pattern; (2) tensile fiber strength was 1.5 times the tensile strength of glass fiber. The tensile strength of pandan fiber was 39,036 kg / mm2 while the tensile strength of glass fiber was 21,65 kg / mm2; (3) the tensile strength of natural composites was lower than synthetic composites. Natural composite tensile strength was 3.03 kg / mm2 while tensile strength of synthetic composite was 3.77 kg / mm2; (4) the increase in formalin concentration for pandan fiber immersion media in the range 0 - 35% had an effect on decreasing tensile strength with the equation y = -640.05x3 + 285,12x2 - 36,358x + 39,105 and R2 = 0.9641. In conclusion, fiber from pandan leaves is suitable to be used as a composite material, but a suitable matrix and suitable treatment have not been found.
Analysis of E-learning implementation using Human Organization Technology approach (HOT) Fit Models
Authors: Alfina  , Irfan Rahmatul 
Published: February 2020

Abstract
B-Smart E-Learning system is used to support the learning process in educational institutions to improve the quality of learning. The analysis conducted on the implementation of the UNY B-Smart E-Learning aims to measure the benefits gained from the use of E-Leraning. Previously, B-Smart E- Learning has not been known to provide good analysis inof bo term of Human, Organisation, Technology and users. This study aims to deepen, prove again and give meaning to the results of quantitative and quantitative research on the analysis of elearning implementation using the Human Organisation Technology approach. This research is a combination of research ( mixed methods) with sequential explanatory research type. The measure of elearning implementation at UNY uses a questionnaire arranged according to the Likert scale model with a population of 25,273 people and a sample of 100 people. Based on research that has been done, the overall reliability value obtained is 0.820 with a very strong reliable interpretation.
Dynamically tunable Fano resonance with high Q factor based on asymmetric Dirac semimetal split-ring structure
Authors: Yan Shuai , Song Shijie , Zhang Huiyun , Zhang Yuping 
Published: February 2020

Abstract
We propose an asymmetric split-ring (ASR) structure based on Dirac semimetal, which has Fano resonance with a high quality (Q) factor in the terahertz (THz) band, the Q factor can reach a maximum value of 20.19. Amplitude modulation can be achieved by increasing the degree of asymmetry Δθ of the asymmetric split ring. As a result, in this study, an amplitude modulation of 27.19% has been achieved by increasing the asymmetry from 10° to 40°. Furthermore, our full-wave electromagnetic simulations show that the frequency sensitivity values of Fano and quadrupole resonance are as high as 0.6 THz/refractive index unit (RIU) and 0.933 THz/RIU, respectively. In addition, the sensing range can be adjusted by changing the Fermi levels of Dirac semimetal. Our study can guide the practical application of ultrasensitive THz sensors.
Glass depolymerization in the process of long-term corrosion: A study of deteriorating semiopaque turquoise glass beads using micro-FTIR spectroscopy
Authors: Kadikova Irina F , Morozova Ekaterina A , Yuryeva Tatyana V , Grigorieva Irina A , Yuryev Vladimir A 
Published: February 2020

Abstract
Nowadays, a problem of historical beadworks conservation in museum collections is actual more than ever because of fatal corrosion of the 19th century glass beads. Study of the beads at different stages of glass corrosion using FTIR was carried out in the attenuated total reflection mode in the range from 200 to 4000 cm−1. We have observed glass depolymerization in the degraded beads, which is exhibited in domination of the band peaked at ∼1000 cm−1. We conclude that the simplification of the glass structure during its long-term degradation at room temperature may be explained within the thermal-fluctuation theory of materials fracture. We consider glass depolymerization, caused by the internal stress and decreasing the glass strength, as an essential corrosion mechanism of strongly stressed glass. We have also revealed shifts of two major absorption bands to low-frequency range (∼1000 and ∼775 cm−1) compared to ones typical for amorphous SiO2 (∼1100 and 800 cm−1, respectively) connected with Pb2+ and K+ appending to the glass network. The presence of a weak band at ∼1630 cm−1 in all the spectra is attributed to the adsorption of H2O. After annealing of the beads, the latter band disappeared completely in less deteriorated samples and significantly weakened in more degraded ones. Based on that we conclude that there is molecular water adsorbed on the beads. However, products of corrosion (e.g., alkali in the form of white crystals or droplets of liquid alkali) were not observed on the surface.
High correlation but high scale-dependent variance between satellite measured night lights and terrestrial exposure
Authors: Simons Ariel Levi , Yin Xiaozhe , Longcore Travis 
Published: February 2020

Abstract
Exposure to artificial light at night (ALAN) is a significant factor in ecological and epidemiological research. Although levels of exposure are frequently estimated from satellite-based measurements of upward radiance, and the correlation between upward radiance and zenith sky brightness is established, the correlation between upward radiance and the biologically relevant exposure to light experienced from all directions on the ground has not been investigated. Because ground-based exposure to ALAN can depend on local glare sources and atmospheric scattering, ecological and epidemiological studies using upward radiance have relied on an untested relationship. To establish the nature of the relationship between upward radiance and hemispherical scalar illuminance (SI) on the ground and to calibrate future experimental studies of ALAN, we used hemispheric digital photography to measure SI at 515 locations in coastal southern California, and compared those values to co-located satellite-based measures of upward radiance as described by the Visible Infrared Imaging Radiometer Suite (VIIRS) satellite’s Day-Night Band (DNB) sensor and zenith downwards radiance as estimated by the World Atlas of Artificial Night Sky Brightness (WA). We found significant variations in SI within the geographic scale defined by the resolutions of both the DNB and WA, as well as in both luminance and color correlated temperature (CCT) across individual image hemispheres. We observed up to two or more orders of magnitude in ALAN exposure within any given satellite-measured unit. Notwithstanding this variation, a linear model of log(SI) (log(SImodeled)), dependent only on the percent of the image hemisphere obscured by structures along the horizon (percent horizon) and log(WA) accounted for 76% of the variation in observed log(SI). DNB does not perform as well in alternative models and consequently future studies seeking to characterize the light environment should be built on WA data when the high temporal resolution of DNB measurements are not needed.
Adiposity, Depression Symptoms and Inflammation in Hispanic/Latino Youth: Results From HCHS/SOL Youth
Authors: Nguyen-Rodriguez Selena T , Gallo Linda C , Isasi Carmen R , Buxton Orfeu M , Thomas KaMala S , Sotres-Alvarez Daniela , Redline Susan , Castañeda Sheila F , Carnethon Mercedes R , Daviglus Martha L , Perreira Krista M 
Published: February 2020

Abstract

Background
Inflammation is implicated as one of many factors related to the development of chronic disease; thus, identifying its modifiable risk factors offers potential intervention targets to reduce risk.

Purpose
To investigate whether depression and anxiety symptoms may indirectly affect high-sensitivity C-reactive protein (hs-CRP) and plasminogen activator inhibitor-1 (PAI-1) through sleep duration and adiposity (i.e., percentage body fat and waist circumference).

Methods
Multiple regression analyses were performed on Hispanic Community Health Study/Study of Latinos Youth (ages 8–16 years) cross-sectional baseline data, which were weighted to adjust for sampling design. Data were collected at a clinical assessment, including fasting blood samples, self-report surveys, and objectively measured anthropometrics.

Results
Adjusting for sociodemographic covariates, depression symptoms were associated with log hs-CRP (β = .011, p = .047) but not PAI-1 (p = .285). Percentage body fat and waist circumference were positively related to depression symptoms (p = .026 and p = .028, respectively) and log hs-CRP (p &lt; .001 for both). When including adiposity in the hs-CRP model, the associations of depression symptoms with hs-CRP were attenuated and became nonsignificant. Monte Carlo confidence intervals (CIs) showed that the indirect effects from depression symptoms to CRP through percentage body fat (95% CI: .0006, .0119) and waist circumference (95% CI: .0004, .0109) were statistically significant.

Conclusions
Results indicate that the association between psychological distress and inflammation may occur indirectly through adiposity in Hispanic/Latino children. If findings are replicated in causal designs, reducing depression symptoms and adiposity among Hispanic/Latino children may be avenues for primary prevention of inflammation in later years.
Investment Case for a Comprehensive Package of Interventions Against Hepatitis B in China: Applied Modeling to Help National Strategy Planning
Authors: Nayagam Shevanthi , Chan Polin , Zhao Kun , Sicuri Elisa , Wang Xiaochun , Jia Jidong , Wei Lai , Walsh Nick , Rodewald Lance E , Zhang Guomin , Ailing Wang , Zhang Lan , Chang Joo H , Hou WeiWei , Qiu Yingpeng , Sui Binyan , Xiao Yue , Zhuang Hui , Thursz M R , Scano Fabio , Low-Beer Daniel , Schwartländer Bernhard , Wang Yu , Hallett Timothy B 
Published: February 2020

Abstract

Background
In 2016, the first global viral hepatitis elimination targets were endorsed. An estimated one-third of the world’s population of individuals with chronic hepatitis B virus (HBV) infection live in China and liver cancer is the sixth leading cause of mortality, but coverage of first-line antiviral treatment was low. In 2015, China was one of the first countries to initiate a consultative process for a renewed approach to viral hepatitis. We present the investment case for the scale-up of a comprehensive package of HBV interventions.

Methods
A dynamic simulation model of HBV was developed and used to simulate the Chinese HBV epidemic. We evaluated the impact, costs, and return on investment of a comprehensive package of prevention and treatment interventions from a societal perspective, incorporating costs of management of end-stage liver disease and lost productivity costs.

Results
Despite the successes of historical vaccination scale-up since 1992, there will be a projected 60 million people still living with HBV in 2030 and 10 million HBV-related deaths, including 5.7 million HBV-related cancer deaths between 2015 and 2030. This could be reduced by 2.1 million by highly active case-finding and optimal antiviral treatment regimens. The package of interventions is likely to have a positive return on investment to society of US$1.57 per US dollar invested.

Conclusions
Increases in HBV-related deaths for the next few decades pose a major public health threat in China. Active case-finding and access to optimal antiviral treatment are required to mitigate this risk. This investment case approach provides a real-world example of how applied modeling can support national dialog and inform policy planning.
Detection of ctDNA from Dried Blood Spots after DNA Size Selection
Authors: Heider Katrin , Wan Jonathan C M , Hall James , Belic Jelena , Boyle Samantha , Hudecova Irena , Gale Davina , Cooper Wendy N , Corrie Pippa G , Brenton James D , Smith Christopher G , Rosenfeld Nitzan 
Published: February 2020

Abstract

Background
Recent advances in the study and clinical applications of circulating tumor DNA (ctDNA) are limited by practical considerations of sample collection. Whole-genome sequencing (WGS) is increasingly used for analysis of ctDNA, identifying copy-number alterations and fragmentation patterns. We hypothesized that low-depth/shallow WGS (sWGS) data may be generated from minute amounts of cell-free DNA, and that fragment-size selection may remove contaminating genomic DNA from small blood volumes. Dried blood spots have practical advantages for sample collection, may facilitate serial sampling, and could support novel study designs in humans and animal models.

Methods
We developed a protocol for the isolation and analysis of cell-free DNA from dried blood spots using filter paper cards and bead-based size selection. DNA extracted and size-selected from dried spots was analyzed using sWGS and polymerase chain reaction (PCR).

Results
Analyzing a 50 μL dried blood spot from frozen whole blood of a patient with melanoma, we identified ctDNA based on the presence of tumor-specific somatic copy-number alterations, and found a fragment-size profile similar to that observed in plasma DNA. We found alterations in different chromosomes in blood spots from 2 patients with high-grade serous ovarian carcinoma. Extending this approach to serial dried blood spots from mouse xenograft models, we detect tumor-derived cell-free DNA and identified ctDNA from the originally grafted ascites.

Conclusion
Our data suggest that ctDNA can be detected and monitored in dried blood spots from archived and fresh blood samples, enabling new approaches for sample collection and novel study/trial designs for both patients and in vivo models.
All-cause mortality, stroke, and bleeding in patients with atrial fibrillation and valvular heart disease
Authors: Strange Jarl Emanuel , Sindet-Pedersen Caroline , Staerk Laila , Grove Erik Lerkevang , Gerds Thomas Alexander , Torp-Pedersen Christian , Gislason Gunnar H , Olesen Jonas Bjerring 
Published: February 2020

Abstract

Aims
To compare the risk of all-cause mortality, stroke, and bleeding in patients with atrial fibrillation (AF) and valvular heart disease (VHD) treated with vitamin K antagonist (VKA) or factor Xa-inhibitors (FXa-I; rivaroxaban and apixaban).

Methods and results
We cross-linked data from Danish nationwide registries identifying patients with AF and VHD (aortic stenosis/insufficiency, mitral insufficiency, bioprosthetic heart valves, mitral-, and aortic valve repair) initiating VKA or FXa-I between January 2014 and June 2017. Outcomes were all-cause mortality, stroke, and bleeding. Using cause-specific Cox regression, we reported the standardized absolute 2-year risk of the outcomes and absolute risk differences (ARD). We identified 1115 (41.7%), 620 (23.1%), and 942 (35.2%) patients initiating treatment with VKA, rivaroxaban, and apixaban, respectively. The standardized absolute risk (95% confidence interval) of all-cause mortality associated with VKA treatment was 34.1% (30.4–37.8%) with corresponding ARD for FXa-I of −2.7% (−6.7% to 1.4%). The standardized absolute risk of stroke for VKA was 3.8% (2.2–5.4%) with corresponding ARD for FXa-I of –0.1% (−2.0% to 1.8%). The standardized risk of bleeding for VKA was 10.4% (7.2–12.9%) with corresponding ARD for FXa-I of –2.0% (−5.1% to 1.1%). The risk of bleeding was significantly reduced in subgroup analyses of apixaban compared with VKA [ARD: −3.9% (−7.0% to −0.9%)] and rivaroxaban [ARD: −5.6% (−9.5% to −1.7%)].

Conclusion
In this nationwide cohort study, there were no significant differences in the risks of all-cause mortality, stroke, and bleeding in patients with AF and VHD treated with VKA compared with FXa-I.
Simultaneous visualization of pulmonary nodules and intersegmental planes on fluorescent images in pulmonary segmentectomy
Authors: Kim Yeasul , Rho Jiyun , Quan Yu Hua , Choi Byeong Hyeon , Han Kook Nam , Kim Hyun Koo , Choi Young Ho 
Published: February 2020

Abstract

OBJECTIVES
The technique of simultaneously visualizing pulmonary nodules and the intersegmental plane using fluorescent images was developed to measure the distance between them intraoperatively.

METHODS
Patients who underwent pulmonary segmentectomy were consecutively included in this study between March 2016 and July 2019. Computed tomography or electromagnetic bronchoscopy-guided localization with indocyanine green–lipiodol emulsion was performed on the day of surgery. In the middle of the surgery, after dividing the segmental artery, vein and bronchus to a targeted segment, 0.3–0.5 mg/kg of indocyanine green was injected intravenously.

RESULTS
In total, 31 patients (17 men and 14 women with a mean age of 63.2 ± 9.8 years) were included in this study. The mean size and depth of the nodules were 1.2 ± 0.5 (range 0.3–2.5) cm and 16.4 ± 9.9 (range 1.0–42.0) mm, respectively. Pulmonary nodules and intersegmental plane of all the patients were visualized using a fluorescent thoracoscope. The resection margins were more than the size of the tumour or were 2 (mean 2.4 ± 1.2) cm in size in all patients except one. The resection margin of this patient looked sufficient on the intraoperative view. However, adenocarcinoma in situ at the resection margin was identified based on the pathological report. The mean duration of the operation was 168.7 ± 53.3 min, and the chest tube was removed on an average of 4.7 ± 1.8 days after surgery in all patients.

CONCLUSIONS
The dual visualization technique using indocyanine green could facilitate an easier measurement of the distance between pulmonary nodules and the intersegmental plane during pulmonary segmentectomy.
Inferring putative ancient whole-genome duplications in the 1000 Plants (1KP) initiative: access to gene family phylogenies and age distributions
Authors: Li Zheng , Barker Michael S 
Published: February 2020

Abstract

Background
Polyploidy, or whole-genome duplications (WGDs), repeatedly occurred during green plant evolution. To examine the evolutionary history of green plants in a phylogenomic framework, the 1KP project sequenced &gt;1,000 transcriptomes across the Viridiplantae. The 1KP project provided a unique opportunity to study the distribution and occurrence of WGDs across the green plants. As an accompaniment to the capstone publication, this article provides expanded methodological details, results validation, and descriptions of newly released datasets that will aid researchers who wish to use the extended data generated by the 1KP project.

Results
In the 1KP capstone analyses, we used a total evidence approach that combined inferences of WGDs from Ks and phylogenomic methods to infer and place 244 putative ancient WGDs across the Viridiplantae. Here, we provide an expanded explanation of our approach by describing our methodology and walk-through examples. We also evaluated the consistency of our WGD inferences by comparing them to evidence from published syntenic analyses of plant genome assemblies. We find that our inferences are consistent with whole-genome synteny analyses and our total evidence approach may minimize the false-positive rate throughout the dataset.

Conclusions
We release 383,679 nuclear gene family phylogenies and 2,306 gene age distributions with Ks plots from the 1KP capstone paper. These resources will be useful for many future analyses on gene and genome evolution in green plants.