bluuebunny/crossref_metadata_2025_split huggingface dataset:
Did the Climate Forecast System Anticipate the 2015 Caribbean Drought?
Authors: Miller Paul W. , Ramseyer Craig A. 
Published: April 2020

AbstractIn groundwater-limited settings, such as Puerto Rico and other Caribbean islands, societal, ecological, and agricultural water needs depend on regular rainfall. Though long-range numerical weather predication models explicitly predict precipitation, such quantitative precipitation forecasts (QPF) critically failed to detect the historic 2015 Caribbean drought. Consequently, this work examines the feasibility of developing a drought early warning tool using the Gálvez–Davison index (GDI), a tropical convective potential index, derived from the Climate Forecast System, version 2 (CFSv2). Drought forecasts are focused on Puerto Rico’s early rainfall season (ERS; April–July), which is susceptible to intrusions of strongly stable Saharan air and represents the largest source of hydroclimatic variability for the island. A fully coupled atmosphere–ocean–land model, the CFSv2 can plausibly detect the transatlantic advection of low-GDI Saharan air with multimonth lead times. The mean ERS GDI is calculated from semidaily CFSv2 forecasts beginning 1 January of each year between 2012 and 2018 and monitored as the initialization approaches 1 April. The CFSv2 demonstrates a broad region of statistically significant correlations with observed GDI across the eastern Caribbean up to 30 days prior to the ERS. During 2015, the CFSv2 forecast a low-GDI tongue extending across the Atlantic toward the Caribbean with 60–90 days lead time and placed Puerto Rico’s 2015 ERS beneath the 15th percentile of all 1982–2018 ERS forecasts with up to 30 days lead time. A preliminary GDI-based QPF tool tested herein is a statistically significant improvement over climatology for the driest years.
Ducting and Biases of GPS Radio Occultation Bending Angle and Refractivity in the Moist Lower Troposphere
Authors: Feng Xuelei , Xie Feiqin , Ao Chi O. , Anthes Richard A. 
Published: April 2020

AbstractRadio occultation (RO) can provide high-vertical-resolution thermodynamic soundings of the planetary boundary layer (PBL). However, sharp moisture gradients and strong temperature inversion lead to large gradients in refractivity N and often cause ducting. Ducting results in systematically negative RO N biases resulting from a nonunique Abel inversion problem. Using 8 years (2006–13) of Constellation Observing System for Meteorology, Ionosphere and Climate (COSMIC) RO soundings and collocated European Centre for Medium-Range Weather Forecasts interim reanalysis (ERA-I) data, we confirm that the large lower-tropospheric negative N biases are mainly located in the subtropical eastern oceans and we quantify the contribution of ducting for the first time. The ducting-contributed N biases in the northeast Pacific Ocean (160°–110°W; 15°–45°N) are isolated from other sources of N biases using a two-step geometric-optics simulation. Negative bending angle biases in this region are also observed in COSMIC RO soundings. Both the negative refractivity and bending angle biases in COSMIC soundings mainly lie below ~2 km. Such bending angle biases introduce N biases that are in addition to those caused by ducting. Following the increasing PBL height from the southern California coast westward to Hawaii, centers of maxima bending angles and N biases tilt southwestward. In areas where ducting conditions prevail, ducting is the major cause of the RO N biases. Ducting-induced N biases with reference to ERA-I compose over 70% of the total negative N biases near the southern California coast, where strongest ducting conditions prevail, and decrease southwestward to less than 20% near Hawaii.
Forecasting Peak Wind Gusts Using Meteorologically Stratified Gust Factors and MOS Guidance
Authors: Kahl Jonathan D. W. 
Published: April 2020

Abstract
Gust prediction is an important element of weather forecasting services, yet reliable methods remain elusive. Peak wind gusts estimated by the meteorologically stratified gust factor (MSGF) model were evaluated at 15 locations across the United States during 2010–17. This model couples gust factors, site-specific climatological measures of “gustiness,” with wind speed and direction forecast guidance. The model was assessed using two forms of model output statistics (MOS) guidance at forecast projections ranging from 1 to 72 h. At 11 of 15 sites the MSGF model showed skill (improvement over climatology) in predicting peak gusts out to projections of 72 h. This has important implications for operational wind forecasting because the method can be utilized at any location for which the meteorologically stratified gust factors have been determined. During particularly windy conditions the MSGF model exhibited skill in predicting peak gusts at forecast projections ranging from 6 to 72 h at roughly half of the sites analyzed. Site characteristics and local wind climatologies were shown to exert impacts on gust factor model performance. The MSGF method represents a viable option for the operational prediction of peak wind gusts, although model performance will be sensitive to the quality of the necessary wind speed and direction forecasts.
Augmenting posterolateral fusion with transforaminal lumbar interbody fusion cage improves clinical outcome, but not fusion rate, of posterior decompression
Authors: Atici Teoman , Yerebakan Selcan , Ermutlu Cenk , Özyalçın Ali 
Published: April 2020

Objective This study was performed to compare fusion rates and clinical outcomes of posterior decompression by posterolateral fusion (PLF) versus transforaminal lumbar interbody fusion (TLIF) for treatment of lumbar spinal stenosis. Methods This retrospective cohort study involved 157 patients with lumbar spinal stenosis treated with instrumented PLF alone or instrumented PLF combined with TLIF from 2010 to 2018. The patients were divided into two groups: the PLF group (Group A), in which posterior decompression with instrumented PLF was performed, and the cage-augmented group (Group B), in which TLIF was added to the procedures described for the PLF group. Patient outcomes (Oswestry Disability Index, visual analog scale score, and 36-Item Short-Form Health Survey scores) and fusion rates were compared. Results The fusion rate was similar between the two groups. Among patients with two- and three-level fusion, improvements in the clinical outcome scores were significantly greater in Group B than Group A. Conclusion Combining TLIF with PLF provides better clinical outcomes than PLF alone when multilevel fusion is indicated. TLIF augmentation does not improve the fusion rates in either single- or multi-level surgery.
Outcome of patients with chlorpyrifos intoxication
Authors: Liu H-F , Ku C-H , Chang S-S , Chang C-M , Wang I-K , Yang H-Y , Weng C-H , Huang W-H , Hsu C-W , Yen T-H 
Published: April 2020

Introduction: There is a paucity of literature analyzing outcome of chlorpyrifos intoxication. Methods: A total of 40 patients with chlorpyrifos intoxication were seen at Chang Gung Memorial Hospital between 2008 and 2017. Patients were stratified into two subgroups according to their prognosis, as good ( n = 12) or poor ( n = 28). Good prognosis group were defined as patients who survived without serious complications, and poor prognosis group included patients who died and survived after development of severe complications. Demographic, clinical, laboratory, and mortality data were obtained for analysis. Results: Patients aged 53.8 ± 16.3 years and most were male (80.0%). All patients (100.0%) developed acute cholinergic crisis such as emesis (45.0%), respiratory failure (42.5%), tachycardia (30.0%), kidney injury (22.5%), and seizure (7.5%). Intermediate syndrome developed in 12.5% of patients, but none had delayed neuropathy (0%). The poor prognosis group suffered higher incidences of respiratory failure ( p = 0.011), kidney injury ( p = 0.026), and prolonged corrected QT interval ( p = 0.000), and they had higher blood urea nitrogen level ( p = 0.041), lower Glasgow coma scale score ( p = 0.011), and lower monocyte count ( p = 0.023) than good prognosis group. All patients were treated with atropine and pralidoxime therapy, but six patients (15.0%) still died of intoxication. In a multivariate logistic regression model, blood urea nitrogen was a significant risk factor for poor prognosis (odds ratio: 1.375, 95% confidence interval: 1.001–1.889, p = 0.049). Nevertheless, no mortality risk factor could be identified. Conclusion: The mortality rate of patients with chlorpyrifos intoxication was 15.0%. Furthermore, acute cholinergic crisis, intermediate syndrome, and delayed neuropathy developed in 100.0%, 12.5%, and 0% of patients, respectively.
Risk of acute kidney injury after contrast-enhanced computed tomography in emergency department
Authors: Dağar Seda , Emektar Emine , Uzunosmanoğlu Hüseyin , Çorbacıoğlu Şeref Kerem , Öztekin Özge , Çevik Yunsur 
Published: April 2020

Background: Despite its risks associated with renal injury, intravenous contrast media increases diagnostic efficacy and hence the chance of early diagnosis and treatment, which leaves clinicians in a dilemma regarding its use in emergency settings. Objective: The aim of this study was to determine the risk and predictors of contrast-induced acute kidney injury following intravenous contrast media administration for computed tomography in the emergency department. Methods: All patients aged 18 years and older who had a basal creatinine measurement within the last 8 h before contrast-enhanced computed tomography and a second creatinine measurement within 48–72 h after computed tomography scan between 1 January 2015 and 31 December 2017 were included in the study. Characteristics of patients with and without contrast-induced acute kidney injury development were compared. Multivariate regression analysis was used to assess the predictors for contrast-induced acute kidney injury. Results: A total of 631 patients were included in the final statistical analysis. After contrast media administration, contrast-induced acute kidney injury developed in 4.9% ( n = 31) of the patients. When the characteristics of patients are compared according to the development of contrast-induced acute kidney injury, significant differences were detected for age, initial creatinine, initial estimated glomerular filtration rate, and all acute illness severity indicators (hypotension, anemia, hypoalbuminemia, and need for intensive care unit admission). A multivariate logistic regression analysis was performed. The need for intensive care unit admission (odds ratio: 6.413 (95% confidence interval: 1.709–24.074)) and hypotension (odds ratio: 5.575 (95% confidence interval: 1.624–19.133)) were the main factors for contrast-induced acute kidney injury development. Conclusion: Our study results revealed that hypotension, need for intensive care, and advanced age were associated with acute kidney injury in patients receiving contrast media. Therefore, we believe that to perform contrast-enhanced computed tomography in emergency department should not be decided only by checking for renal function tests and that these predictors should be taken into consideration.
Point-of-care ultrasound for assessing arteriovenous fistula maturity in outpatient hemodialysis
Authors: Coritsidis George N , Machado Orlando N , Levi-Haim Farzin , Yaphe Sean , Patel Roshan A , Depa Jayaramakrishna 
Published: April 2020

Background: Point-of-care ultrasound in end-stage renal disease is on the rise. Presently the decision to cannulate an arteriovenous fistula is based on its duration since surgery and physical exam. This study examines the effects of point-of-care ultrasound on decreasing the time to arteriovenous fistula cannulation, time spent with a central venous catheter, and the complications and infections that arise. Methods: Prospective point-of-care ultrasound patients were recruited between January 2015 and January 2018, while retrospective data (non-point-of-care ultrasound) were collected via chart review from patients who had fistula creation between November 2011 and May 2014. Patients had point-of-care ultrasound within 3 weeks after arteriovenous fistula creation and were followed for 1 year. Arteriovenous fistula cannulation was initiated when the following parameters were met: diameter > 6 mm (with no depreciable narrowing of more than 20% throughout), depth < 6 mm, and length > 6 cm. Demographic data, as well as time to cannulation and central venous catheter removal, number of infections, complications, and interventions were compared between point-of-care ultrasound and non-point-of-care ultrasound groups using unpaired t-test, chi-square, and Fisher exact test statistical analysis. Results: A total of 37 patients with new arteriovenous fistulas were followed by point-of-care ultrasound compared to 29 non-point-of-care ultrasound patients. Point-of-care ultrasound patients had earlier cannulations (35.5 vs 63.3 days, p < 0.05), shorter central venous catheter duration (68.2 vs 98.3 days, p < 0.05), and less infections (12 vs 19) without differences in complication compared to the non-point-of-care ultrasound. Conclusion: Point-of-care ultrasound facilitates early and safe arteriovenous fistula cannulation leading to a reduction in central venous catheter time and risk of infection. Point-of-care ultrasound may also aid in earlier identification of complications and difficult cannulations.
A chrome cobalt mandibular advancement appliance for snoring and obstructive sleep apnoea used during active aligner orthodontic treatment
Authors: Ash Simon 
Published: April 2020

Adult orthodontics is now mainstream, made all the more acceptable by the advent of removable aligners. These patients may also coincidentally suffer from snoring and obstructive sleep apnoea (OSA), for which the indefinite wearing of a mandibular advancement device (MAD) during sleep may be required. Indefinite removable nocturnal orthodontic retention is now established practice. This case report describes a cast chrome cobalt MAD and its application in the management of a patient who, having very successfully managed his snoring and mild OSA with a removable cast chrome cobalt MAD, wished to continue this management while undergoing active orthodontic treatment using removable aligners. He also wished to wear a chrome cobalt MAD to incorporate orthodontic retention and inter occlusal splinting as part of his MAD on completion of his active orthodontic treatment.
Associated factors and impacts of sedentary behaviour in patients with heart failure: A longitudinal study
Authors: Chen Mei-Fang , Ke Shin-Rong , Liu Chih-Ling , Wu Tao-Cheng , Yu Ya-Mei , Chiou Ai-Fu 
Published: April 2020

Background:Sedentary behaviours may be related to factors such as self-efficacy, mood and social support. However, there is a paucity of longitudinal follow-up studies examining factors related to sedentary behaviour from physical-psychosocial perspectives in patients with heart failure.Aims:The purpose of this study was to explore the multidimensional associated factors and impacts of sedentary behaviour in heart failure patients.Methods:A longitudinal design was used. A convenience sample of 128 heart failure patients recruited from two large medical centres in northern Taiwan was obtained. Patients were interviewed with structured questionnaires to assess physical activity, symptom distress, exercise self-efficacy, anxiety and depression, social support, sleep quality and quality of life before discharge and at 3 and 6 months after discharge.Results:Heart failure patients reported low physical activity and tended to be sedentary. Sedentary behaviour was gradually reduced from hospitalization to 6 months after discharge. Sleep quality, quality of life, analgesic use, symptom distress and exercise self-efficacy were significant associated factors that explained 42.1–51% of the variance in sedentary behaviour. Patients with high sedentary behaviour had significantly greater depression and poorer sleep and quality of life than those with low sedentary behaviour at hospitalization and showed a significant improvement in depression at 3 and 6 months after discharge.Conclusion:Sedentary behaviour is common in heart failure patients and has impacts on depression and quality of life. An appropriate physical activity programme focusing on disease self-management and enhancing self-efficacy is needed for heart failure patients to improve their sedentary behaviour and quality of life.
The paradoxes of practical research: The good intentions of inclusion that exclude and abject
Authors: Popkewitz Thomas S 
Published: April 2020

There is an alluring, daunting, and haunting desire for practical knowledge in the contemporary social and education sciences about school change. This desire is not new: it haunts the turn of 20th century social sciences to change urban conditions and populations, and appears today in international school assessments and professional education. The article explores the paradoxes of practical research through a history of the present. Different historical lines activated in contemporary research are discussed: (a) the object of practical knowledge is making kinds of people; (b) the sciences about changing the present embody desires about the potentialities of society and people that research is to actualize; and (c) the “useful, practical knowledge” paradoxically embodies comparative styles of reasoning that inscribe inequality in the search for equality. The argument focuses on science as “an actor” in governing. It argues that governing in modernity occurs less through brute force (although it is still present) and more through the principles that order and classify conduct. The sciences of the modern school are central in this governing. The article methodologically draws on social and cultural histories, science and technology studies, and studies of the politics of knowledge.
Pulmonary complications and survival after elective infrarenal endovascular abdominal aneurysm repair in patients with documented chronic obstructive pulmonary disease
Authors: Oussoren Fieke K , Holewijn Suzanne , Claessens Niels , van der Veen Daphne , Reijnen Michel MPJ 
Published: April 2020

Background Elective abdominal aortic aneurysm (AAA) repair is advocated in patients where risk of rupture exceeds the risks of peri-procedural morbidity and mortality. Chronic obstructive pulmonary disease (COPD) is a known risk factor for AAA and increased operative morbidity in general. Since literature on the correlation between the clinical classification of COPD and morbidity following endovascular infrarenal AAA repair (EVAR) is scarce, assessment per individual remains a challenge. Objective To analyse the pulmonary and all-cause morbidity and mortality in patients with documented COPD and relate this to their GOLD classification. Methods Sixty-eight patients with COPD, documented by a lung function test, who underwent elective EVAR between July 2002 and July 2018 were retrospectively reviewed. The primary endpoint was the incidence of 30-day pulmonary adverse events. Procedural characteristics, length of hospital stay, pulmonary and all-cause morbidity including major adverse events (MAEs) during follow-up and five-year survival divided per GOLD classification were the secondary endpoints. Results There was no statistically significant difference in the incidence of pulmonary adverse events between GOLD I/II and GOLD III/IV patients. There was neither procedural nor 30-day mortality in either group. Through 30 days and 1 year, there was no difference in pulmonary and all-cause morbidity between groups. Three MAEs occurred in the GOLD I/II group versus 2 MAE in the GOLD III/IV group during the first postoperative year. The five-year survival was 66.0%, 60.9% and 61.9% for patients with GOLD I, GOLD II and GOLD III, respectively. Three of four GOLD IV died within the first year after EVAR. Conclusion EVAR can be safely performed in patients with COPD, with low 30-day morbidity and mortality rates. Although severe co-morbidity should be taken into account, EVAR seems to be justified in patients with COPD with a GOLD classification I, II or III. Further research should focus on optimising the pulmonary condition in patients selected for EVAR.
Second-line treatment in patients with advanced extra-pulmonary poorly differentiated neuroendocrine carcinoma: a systematic review and meta-analysis
Authors: McNamara Mairéad G. , Frizziero Melissa , Jacobs Timothy , Lamarca Angela , Hubner Richard A. , Valle Juan W. , Amir Eitan 
Published: April 2020

Background: There is no standard second-line treatment for patients with advanced extra-pulmonary poorly differentiated neuroendocrine carcinoma (EP-PD-NEC). This study explored data evaluating second-line treatment in these patients. Methods: A search of MEDLINE and EMBASE identified studies reporting survival and/or response data for patients with EP-PD-NEC receiving second-line therapy. Association between various factors (age, gender, ECOG performance status, primary tumour location, morphology, Ki-67, treatment and grade 3/4 haematological toxicity) and response rate (RR), progression-free (PFS) and overall survival (OS) were assessed with a mixed effects meta-regression weighted by individual study sample size. Due to a small sample size, associations were reported quantitatively, based on magnitude of beta coefficient rather than statistical significance. Results: Of 83 identified studies, 19 were eligible, including 4 prospective and 15 retrospective studies. Analysis comprised 582 patients, with a median number of 19 patients in each study (range 5–100). Median age was 59 years (range 53–66). Median RR was 18% (range 0–50; 0% for single-agent everolimus, temozolomide, topotecan; 50% with amrubicin), median PFS was 2.5 months (range 1.15–6.0) and median OS was 7.64 months (range 3.2–22.0). Studies with a higher proportion of patients with a Ki-67>55% had lower RR (β = –0.73) and shorter OS (β = –0.82). Conclusion: Second-line therapy for patients with advanced EP-PD-NEC has limited efficacy and the variety of regimens used is diverse. Ki-67>55% is associated with worse outcomes. Prospective randomised studies are warranted to enable exploration of new treatment strategies.
Implementation of the Global Compact on Safe, Orderly, and Regular Migration: A Whole-of-Society Approach
Authors: Appleby J. Kevin 
Published: April 2020

Executive Summary The Global Compact on Safe, Orderly, and Regular Migration (GCM) provides a blueprint for nations to manage migration flows through multilateral cooperation. Nations are best served by partnering with a wide range of societal actors to implement the objectives of the GCM. Such civil society actors may include non-profit organizations, faith-based groups, the private sector, trade unions, and academia, among other relevant stakeholders. Each of these actors brings unique strengths to the implementation of the GCM, filling gaps in the care and protection of migrants. They perform tasks that governments are unable or unwilling to undertake, especially in the area of irregular migration. A “whole-of-society” approach is the most effective method for managing migration humanely and in concert with the rule of law.