bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hysteresis in the normal rate of capacity utilization: A behavioral explanation
Authors: Setterfield Mark , David Avritzer Joana 
Published: August 2020

AbstractKaleckians describe a normal rate of capacity utilization that is subject to hysteresis effects. This means that the normal rate varies directly with the actual rate of capacity utilization, ensuring that steady‐state equilibrium conditions in the Kaleckian model are fully adjusted (the actual and normal rates of capacity utilization are equalized) but without this last condition implying that the rate of capacity utilization is constant in the long run. The relationship between distribution and growth unique to the Kaleckian model is, thus, preserved. The hysteresis mechanism has been criticized from various quarters, however, these criticisms focusing on its alleged lack of behavioral foundations. This paper shows that consistent with the stylized facts, variation in the normal rate of capacity utilization in response to variation in the actual capacity utilization rate can be derived from the links between both variables and the volatility of the macroeconomic environment—volatility, in the presence of fundamental uncertainty, being an important reason why firms deliberately under‐utilize capacity (even in the long run) in the first place. The result is an empirically grounded behavioral foundation for hysteresis in the normal rate of capacity utilization.
Expanded role of the Cu‐sensing transcription factor Mac1p in Candida albicans
Authors: Culbertson Edward M. , Bruno Vincent M. , Cormack Brendan P. , Culotta Valeria C. 
Published: August 2020

AbstractAs part of the innate immune response, the host withholds metal micronutrients such as Cu from invading pathogens, and microbes respond through metal starvation stress responses. With the opportunistic fungal pathogen Candida albicans, the Cu‐sensing transcription factor Mac1p governs the cellular response to Cu starvation by controlling Cu import. Mac1p additionally controls reactive oxygen species (ROS) homeostasis by repressing a Cu‐containing superoxide dismutase (SOD1) and inducing Mn‐containing SOD3 as a non‐Cu alternative. We show here that C. albicans Mac1p is essential for virulence in a mouse model for disseminated candidiasis and that the cellular functions of Mac1p extend beyond Cu uptake and ROS homeostasis. Specifically, mac1∆/∆ mutants are profoundly deficient in mitochondrial respiration and Fe accumulation, both Cu‐dependent processes. Surprisingly, these deficiencies are not simply the product of impaired Cu uptake; rather mac1∆/∆ mutants appear defective in Cu allocation. The respiratory defect of mac1∆/∆ mutants was greatly improved by a sod1∆/∆ mutation, demonstrating a role for SOD1 repression by Mac1p in preserving respiration. Mac1p downregulates the major Cu consumer SOD1 to spare Cu for respiration that is essential for virulence of this fungal pathogen. The implications for such Cu homeostasis control in other pathogenic fungi are discussed.
The role of Latvian nationalism in the transformation of Lithuanian nationalism during the long 19th century
Authors: Pivoras Saulius 
Published: August 2020

AbstractThis article examines the role of Latvian ethnic nationalism in the transformation of Lithuanian nationalism from a civic to ethnic form during the long 19th century. In particular, the present article aims to clarify the differences between the Lithuanian and Latvian models of national identity in the initial phases of their national movements and to analyse how the Latvian example influenced Lithuanian nationalism. The Latvian model of nationalism, which spread to the Lithuanian context through communication among prominent intellectuals of the national movements at the end of the 19th and early 20th centuries, contributed to the central positioning of an ethnolinguistic identity within the Lithuanian national movement. This article provides compelling evidence that it is relatively easy to transition from civic to ethnic nationalism over a longer time period when the main dimensions of national identity have undergone radical change.
Host selection shapes crop microbiome assembly and network complexity
Authors: Xiong Chao , Zhu Yong‐Guan , Wang Jun‐Tao , Singh Brajesh , Han Li‐Li , Shen Ju‐Pei , Li Pei‐Pei , Wang Gui‐Bao , Wu Chuan‐Fa , Ge An‐Hui , Zhang Li‐Mei , He Ji‐Zheng 
Published: August 2020

Summary

Plant microbiomes are essential to host health and productivity but the ecological processes that govern crop microbiome assembly are not fully known.

Here we examined bacterial communities across 684 samples from soils (rhizosphere and bulk soil) and multiple compartment niches (rhizoplane, root endosphere, phylloplane, and leaf endosphere) in maize (Zea mays)‐wheat (Triticum aestivum)/barley (Hordeum vulgare) rotation system under different fertilization practices at two contrasting sites.

Our results demonstrate that microbiome assembly along the soil‐plant continuum is shaped predominantly by compartment niche and host species rather than by site or fertilization practice. From soils to epiphytes to endophytes, host selection pressure sequentially increased and bacterial diversity and network complexity consequently reduced, with the strongest host effect in leaf endosphere. Source tracking indicates that crop microbiome is mainly derived from soils and gradually enriched and filtered at different plant compartment niches. Moreover, crop microbiomes were dominated by a few dominant taxa (c. 0.5% of bacterial phylotypes), with bacilli identified as the important biomarker taxa for wheat and barley and Methylobacteriaceae for maize.

Our work provides comprehensive empirical evidence on host selection, potential sources and enrichment processes for crop microbiome assembly, and has important implications for future crop management and manipulation of crop microbiome for sustainable agriculture.
Constructing and testing hypotheses of dinosaur foot motions from fossil tracks using digitization and simulation
Authors: Falkingham Peter L. , Turner Morgan L. , Gatesy Stephen M. 
Published: August 2020

AbstractWhilst bones present a static view of extinct animals, fossil footprints are a direct record of the activity and motion of the track maker. Deep footprints are a particularly good record of foot motion. Such footprints rarely look like the feet that made them; the sediment being heavily disturbed by the foot motion. Because of this, such tracks are often overlooked or dismissed in preference for more foot‐like impressions. However, the deeper the foot penetrates the substrate, the more motion is captured in the sediment volume. We have used deep, penetrative, Jurassic dinosaur tracks which have been naturally split into layers, to reconstruct foot motions of animals living over 200 million years ago. We consider these reconstructions to be hypotheses of motion. To test these hypotheses, we use the Discrete Element Method, in which individual particles of substrate are simulated in response to a penetrating foot model. Simulations that produce virtual tracks morphologically similar to the fossils lend support to the motion being plausible, while simulations that result in very different final tracks serve to reject the hypothesis of motion and help generate a new hypothesis.
On what do therapists agree? Assessing therapist evaluations of emotion regulation strategy effectiveness
Authors: Southward Matthew W. , Wilson Anne C. , Cheavens Jennifer S. 
Published: August 2020

ObjectiveTo develop more unified, process‐based, and disseminable psychotherapy treatments, it is important to determine whether there is consensus among therapists regarding intervention strategies.DesignBecause emotion regulation is a cornerstone of modern treatments and a thriving area of clinical research, we assessed therapists’ ratings of the effectiveness of commonly studied emotion regulation strategies.MethodsTherapists (n = 582) read eleven vignettes describing stressful scenarios and rated the effectiveness of ten emotion regulation strategies in each scenario.ResultsAcross therapists, we found general consensus regarding the most (i.e., problem‐solving) and least (i.e., concealing emotions) effective strategies. Cognitive/behavioural/third‐wave therapists rated acceptance and distraction as more effective, and emotional expression and gathering information as less effective, than other therapists,Fs> 4.20,ps < .05, whereas hours of clinical experience were generally unrelated to strategy effectiveness ratings.ConclusionsWe discuss what these points of agreement and relative disagreement among therapists reveal about a more unified, process‐based treatment approach and how these results can guide emotion regulation research.Practitioner pointsThere is general consensus among practising therapists that problem‐solving is the most effective emotion regulation strategy and expressive suppression is the least effective.However, CBT‐oriented therapists rated acceptance and distraction as more effective than non‐CBT‐oriented therapists.Non‐CBT‐oriented therapists rated emotional expression and gathering information as more effective than CBT‐oriented therapists.Years of experience were unrelated to ratings of emotion regulation strategy effectiveness.
Nutrient balances in smallholder farms in northern Ethiopia
Authors: Mesfin Shimbahri , Gebresamuel Girmay , Zenebe Amanuel , Haile Mitiku 
Published: August 2020

AbstractDepletion of soil nutrient is a major impediment for food production in sub‐Saharan Africa, but little is known about nutrient dynamics at the farm level. Therefore, the objective of this study was to evaluate nutrient management on a range of contrasting farms by estimating balances of N, P and K. Representative farmers of three wealth classes (rich, medium and poor) were selected from two different agro‐ecological regions (Alaje and Raya Azebo) in northern Ethiopia. The MonQI model based on data obtained from farm questionnaires was used for processing and analysis of partial nutrient balances (input from mineral and organic fertilizer minus output with crop and straw) and full balances (all input sources minus output with crop, erosion, leaching and gaseous losses). Partial N, P and K balances were 25.6, 6.3 and 7.8 kg ha−1 in Alaje and −7.1, 10.6 and −6.7 kg ha−1 in Raya Azebo. Full N, P and K balances were −26.2, 6.7 and 2.9 kg ha−1 in Alaje and −17.9, 11.1 and −5.3 kg ha−1 in Raya Azebo. Partial N and K and full K balances were different (p < .05) between the regions. Farms owned by rich and poor farmers differed in full N balances in Alaje and in partial N balances in Raya Azebo (p < .05). With the use of more fertilizer, N losses to the environment also increased. Generally, soil stocks of N and K are further declining. There is a need for socio‐economic policies to introduce effective nutrient management on the farms and to provide poorer farmers' access to fertilizer.
Phylogenomics of the lepidopteran endoparasitoid wasp subfamily Rogadinae (Hymenoptera: Braconidae) and related subfamilies
Authors: Jasso‐Martínez Jovana M. , Quicke Donald L. J. , Belokobylskij Sergey A. , Meza‐Lázaro Rubi Nelsi , Zaldívar‐Riverón Alejandro 
Published: August 2020

AbstractRogadinae are a cosmopolitan, species‐rich braconid wasp subfamily whose species are endoparasitoids that attack larvae of a number of lepidopteran families. Members of this subfamily are characterized by pupating within the mummified host larval skin. The subfamily contains six tribes whose relationships have only been partially clarified: Aleiodini, Betylobraconini, Clinocentrini, Rogadini, Stiropiini and Yeliconini. The limits and composition of the closely related subfamilies to the Rogadinae, Hormiinae and Lysiterminae, also remain unclear. Here, we generated ultraconserved element data to reconstruct an almost fully resolved phylogeny for the members of Rogadinae and related subfamilies. Based on our best estimate of phylogeny, we confirm the monophyly of Rogadinae including Betylobraconini, synonymize Xenolobus Fahringer and Bequartia Cameron within the species‐rich genus Aleiodes Wesmael (syn.n.) based on DNA, and synonymize Promesocentrus van Achterberg with Pilichremylus Belokobylskij (syn.n.) based on morphology. We also consistently recovered Hormiinae and Lysiterminae as not reciprocally monophyletic, and thus propose to unite their members under Hormiinae. The ancestral host preference for Rogadinae was probably attacking concealed lepidopteran larvae, with the occurrence of at least two main subsequent transitions to attack both concealed and exposed hosts, one within Rogadini and a second within Aleiodini. We highlight the importance of natural history collections as a source for conducting genomic‐based studies using techniques that allow to obtain a substantial amount of data from considerably old preserved insect specimens.
OpenStreetMap quality assessment using unsupervised machine learning methods
Authors: Jacobs Kent T. , Mitchell Scott W. 
Published: August 2020

AbstractThe reliability and quality of volunteered geographic information (VGI) continue to be pressing concerns. Many VGI projects lack standard geospatial data quality assurance procedures, and the reliability of contributors remains in question. Traditional approaches rely on comparing VGI to an “authoritative” or “gold standard” dataset to assess quality. This study investigates VGI quality by analysing the OpenStreetMap (OSM) database in Ottawa‐Gatineau, focusing on historical map features and contributor data to gain an understanding of how users are contributing to the database, and their ability to do so accurately. Unsupervised machine learning analyses expose a cluster of experienced contributors classified as “OSM validators/experts”, which are then further used to attribute data quality. They are identified through a combination of strong contribution loadings associated with the use and experience of advanced OSM editors, and weaker loadings associated with feature creation and frequency of contributions leading to further correction. Limitations are discussed with implications for future work.
An ethyl methanesulfonate‐induced neutral mutant‐bridging method efficiently identifies spontaneously mutated genes in rice
Authors: Hu Wei , Zhou Tianhao , Hu Gang , Wu Hong , Han Zhongmin , Xiao Jinghua , Li Xianghua , Xing Yongzhong 
Published: August 2020

SUMMARYSpontaneous mutants are mainly obtained from tissue culture or natural occurrences in plants. The traditional strategy for identifying spontaneously mutated genes is to continuously backcross these mutants to another variety and develop a near‐isogenic F2 population for map‐based cloning or bulked segregant analysis. However, this strategy is time‐consuming. Here, we have developed a new method to efficiently accelerate the identification process. The chemical mutagen ethyl methanesulfonate was first used to treat the wild type of the spontaneous mutants to induce thousands of neutral mutations. An induced individual without any statistically significant phenotypic changes which was compared with the wild type was chosen as the neutral mutant. The spontaneous mutant was then crossed with the neutral mutant to develop a pseudo‐near‐isogenic F2 population in which only the induced neutral mutations and the causal mutation were segregated in the genome. This population ensures that the variation of the mutated trait is controlled only by the spontaneously mutated gene. Finally, after sequencing the neutral mutant and the mutant‐type DNA pool of the F2 population the spontaneous mutation will be identified quickly by bioinformatics analysis. Using this method, two spontaneously mutated genes were identified successfully. Therefore, the neutral mutant‐bridging method efficiently identifies spontaneously mutated genes in rice, and its value in other plants is discussed.
Making Sense of Coach Development Worldwide During the COVID-19 Pandemic
Authors: Callary Bettina , Brady Abbe , Kiosoglous Cameron , Clewer Pekka , Resende Rui , Mehrtens Tammy , Wilkie Matthew , Horvath Rita 
Published: August 2020

The commentary brings together the perspectives of a group of coach developers from across the globe who form a community of practice (CoP) from their involvement as “Cohort 5” in the International Council for Coaching Excellence and Nippon Sport Science University Coach Developer Academy. The CoP includes people from three types of organizations: university professors of sport coaching programs, national sport federations, and national multisport organizations’ directors of coach education. While this CoP existed prior to the pandemic, the forced isolation has created a new structure and purpose to the CoP: The authors are all making meaning of the landscape of coach development within which they work by understanding the perspectives of others who work in their domain from across the world and the similar realities that they face in North America, Europe, the United Kingdom, and New Zealand. The authors outline the key themes that emerged from their weekly CoP video conference meetings to shed light on how this pandemic has changed the way they think about coach development.
Equivalency of Sleep Estimates: Comparison of Three Research-Grade Accelerometers
Authors: Plekhanova Tatiana , Rowlands Alex V. , Yates Tom , Hall Andrew , Brady Emer M. , Davies Melanie , Khunti Kamlesh , Edwardson Charlotte L. 
Published: August 2020

Introduction: This study examined the equivalency of sleep estimates from Axivity, GENEActiv, and ActiGraph accelerometers worn on the nondominant and dominant wrists and with and without using a sleep log to guide the algorithm. Methods: 47 young adults wore an Axivity, GENEActiv, and ActiGraph accelerometer continuously on both wrists for 4–7 days. Sleep time, sleep window, sleep efficiency, sleep onset, and wake time were produced using the open-source software (GGIR). For each outcome, agreement between accelerometer brands, dominant and nondominant wrists, and with and without use of a sleep log, was examined using pairwise 95% equivalence tests (±10% equivalence zone) and intraclass correlation coefficients (ICCs), with 95% confidence intervals and limits of agreement. Results: All sleep outcomes were within a 10% equivalence zone irrespective of brand, wrist, or use of a sleep log. ICCs were poor to good for sleep time (ICCs ≥ .66) and sleep window (ICCs ≥ .56). Most ICCs were good to excellent for sleep efficiency (ICCs ≥ .73), sleep onset (ICCs ≥ .88), and wake time (ICCs ≥ .87). There were low levels of mean bias; however, there were wide 95% limits of agreement for sleep time, sleep window, sleep onset, and wake time outcomes. Sleep time (up to 25 min) and sleep window (up to 29 min) outcomes were higher when use of the sleep log was not used. Conclusion: The present findings suggest that sleep outcomes from the Axivity, GENEActiv, and ActiGraph, when analyzed identically, are comparable across studies with different accelerometer brands and wear protocols at a group level. However, caution is advised when comparing studies that differ on sleep log availability.
On the path towards universal coverage of hepatitis C treatment among people receiving opioid agonist therapy (OAT) in Norway: a prospective cohort study from 2013 to 2017
Authors: Aas Christer Frode , Vold Jørn Henrik , Skurtveit Svetlana , Odsbu Ingvild , Chalabianloo Fatemeh , Økland Jan Magnus , Leiva Rafael Alexander Modahl , Vickerman Peter , Johansson Kjell Arne , Fadnes Lars T 
Published: August 2020

ObjectivesWe aimed to calculate cumulative hepatitis C virus (HCV) treatment coverage among individuals enrolled in opioid agonist therapy (OAT) in Norway between 2013 and 2017 and to document the treatment transition to direct-acting antiviral (DAA) agents. Moreover, we aimed to describe adherence to DAAs in the same cohort.DesignProspective cohort, registry data.SettingSpecialist healthcare service (secondary)Participants and outcomesThis observational study was based on data from The Norwegian Prescription Database. We studied dispensed OAT and HCV treatment annually to calculate the cumulative frequency, and employed secondary sources to calculate prevalence, incidence and HCV treatment coverage from 2013 to 2017, among the OAT population. Factors associated with adherence to DAAs were identified a priori and subject to logistic regression.Results10 371 individuals were identified with dispensed OAT, 1475 individuals of these were identified with dispensed HCV treatment. Annual HCV treatment coverage increased from 3.5% (95% CI: 3.2 to 4.4) in 2013 to 17% (95% CI: 17 to 20) in 2017, giving a cumulative HCV coverage among OAT patients in Norway of 38.5%. A complete shift to interferon-free treatment regimens occurred, where DAAs accounting for 32% of HCV treatments in 2013 and 99% in 2017. About two-thirds of OAT patients were considered adherent to their DAA regimens across all genotypes. High level of OAT continuity was associated with improved adherence to DAAs (adjusted OR 1.4, 95% CI: 1 to 2, p=0.035).ConclusionsA large increase in HCV treatment coverage attributed by a complete shift to interferon-free regimens among the Norwegian OAT population has been demonstrated. However, treatment coverage is inadmissibly too low and a further substantial scale-up in HCV treatment is required to reach the universal targets of controlling and eliminating the HCV endemic.
Linear growth and mid-childhood cognitive outcomes in three birth cohorts of term-born children: an approach to integrating three growth models to explore critical windows
Authors: Leung Michael , Krishna Aditi , Yang Seungmi , Bassani Diego G , Roth Daniel E 
Published: August 2020

ObjectiveTo illustrate that a mediation framework can help integrate inferences from three growth models to enable a comprehensive view of the associations between growth during specific developmental windows and mid-childhood IQ.DesignWe analysed direct and indirect associations between mid-childhood IQ and length/height growth in five early-life age intervals bounded by conception, birth, early, mid and late infancy, and mid-childhood using estimates from three growth models (lifecourse, conditional change and change score) applied to three historical birth cohorts.Participants and setting12 088 term-born children from the Collaborative Perinatal Project (CPP) in the USA (n=2170), the Promotion of Breastfeeding Intervention Trial (PROBIT) in Belarus (n=8275) and the Cebu Longitudinal Health and Nutrition Survey (CLHNS) in the Philippines (n=1643).Primary outcome measureMid-childhood IQ.ResultsOur analyses revealed cross-cohort and cross-interval variations in the direct and indirect effects of foetal and early childhood physical growth on mid-childhood IQ. For example, in CPP, there was a direct association of prenatal growth with IQ that was not evident in the other cohorts, whereas in PROBIT and CLHNS, we observed that foetal and early growth-IQ associations were mediated through size in later periods.ConclusionLifecourse, conditional change and change score growth models yield complementary inferences when appropriately interpreted. Future longitudinal studies of associations of early-life growth with later outcomes would benefit from adopting a causal mediation framework to integrate inferences from multiple complementary growth models.