bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and Associated Factors for Depressive Symptomatology in Chinese Adults During COVID-19 Epidemic
Authors: Peng Songxu , Lai Xin , Du Yukai , Li Yuting , Tian Kunming , Gan Yong 
Published: December 2020

Background: The coronavirus disease 2019 (COVID-19) has been rapidly transmitted worldwide, which contributed to various psychological problems (such as fear, depression, and anxiety) among the general population in China. The purpose of this study is to investigate the prevalence and associated factors of depressive symptoms among Chinese adults.Methods: A cross-sectional study of Chinese adults was conducted during 17–29 February 2020. Symptoms of depression were assessed using the Center for Epidemiologic Studies Depression scale (CES-D).Results: A total of 3,399 respondents were included in the analysis. It was observed that 14.2% (481/3,399) of the participants were screened positive for depressive symptoms. In a multivariate logistic regression analysis, older age (OR = 0.98; 95% CI, 0.97–0.99), smoking (OR = 1.57; 95% CI, 1.10–2.26), self-rated health (good: OR = 0.49; 95% CI, 0.37–0.66; fairly: OR = 0.60; 95% CI, 0.45–0.80), having greater support scores (OR = 0.95; 95% CI, 0.94–0.96), knowledge about the main symptom of COVID-19 (very clearly: OR = 0.58; 95% CI, 0.42–0.79; relatively clearly: OR = 0.59; 95% CI, 0.44–0.79), and staying in Wuhan within 3 months before the outbreak of epidemic (OR = 1.78; 95% CI, 1.34–2.38) were associated with depressive symptoms.Conclusion: A considerable proportion of the general population in China had depressive symptoms during the COVID-19 epidemic. Routine screening and targeted interventions for depression are needed among high-risk depressed individuals during the COVID-19 epidemic.
Positive Impact of Professionalism on the Perception of Global Well-Being: A Study in Healthcare Professionals Starting Their First Working Experience in Peruvian Rural Areas
Authors: López-Morales Humberto , Rivera-Diaz Edgar , Ore-Zuñiga Andrew , Vera-Portilla Angel , San-Martín Montserrat , Delgado Bolton Roberto C. , Vivanco Luis 
Published: December 2020

Introduction: In Peru, recently graduated physicians and nurses who are willing to start working in the public healthcare system, first have to work in their newly acquired profession in the programme denominated “Servicio Rural Urbano y Marginal de Salud” (SERUMS). The SERUMS programme is a 1-year contract in rural areas of the country. The aim of this study was to confirm the following hypothesis: the development of abilities associated to professionalism has a positive effect on the perception of global well-being in the professionals beginning SERUMS.Material and methods: In the study two cohorts of medical and nursing professionals that started SERUMS in 2017 and 2019 were included. The perception of global well-being and general health condition were measured with the Scale of Life Satisfaction (SWLS) and the General Health Questionnaire (GHQ-28), respectively. Professionalism was measured using Jefferson's scales of empathy (JSE), teamwork (JSAPNC), and lifelong learning (JeffSPLL). An analysis in phases using the R language was applied to develop a multiple regression model that would explain the lineal relationship between the global perception of well-being and the studied variables.Results: The study sample included 303 professionals (108 men and 195 women) with a mean age of 26 years, ranging from 22 to 39 years (SD = 4). Based on their profession, 230 were medical doctors and 67 were nurses. The multiple regression model evidenced that age (p &lt; 0.001), social dysfunction (p &lt; 0.001), severe depression (p &lt; 0.001), and inter-professional collaborative work abilities (p &lt; 0.001) explain 38% of the variability in the global perception of well-being. Moreover, a second model explained 44% of the variability in the inter-professional collaborative work abilities based on a lineal relationship with empathy (p &lt; 0.001), lifelong learning (p &lt; 0.001), and future professional orientation (p = 0.01). Both models complied with the necessary conditions for statistic inference and showed large effect sizes.Conclusions: These findings confirm that professionalism has an important role in improving the global well-being of the professionals initiating SERUMS. This influence is direct in the case of inter-professional collaborative work, whereas it is indirect in the case of empathy and lifelong learning.
Rule of UA on Cardiac Myocytes Uric Acid Differently Influence the Oxidative Damage Induced by Acute Exposure of High Level of Glucose in Chicken Cardiac Myocytes
Authors: Sun Xiaolong , Jiao Hongchao , Zhao Jingpeng , Wang Xiaojuan , Lin Hai 
Published: December 2020

Background:Uric acid (UA) is a potent scavenger of oxidants in mammalian and avian species. In humans, hyperglycemia with simultaneous hyperuricemia may exert additional damage to the cardiovascular system. Chickens naturally have hyperglycemia (10.1–11.0 mmol/L) and hyperuricemia (100–900 μmol/L), which makes them an interesting model.Methods:The aim of this study was to investigate the effects of UA on the oxidative damage induced by acute exposure of high level of glucose in chicken cardiac myocytes.Results:Cell viability and the concentrations of thiobarbituric acid reactive substance (TBARS) were decreased by glucose treatment in a dose- and time-dependent manner. After acute exposure to high level of glucose (300 mM), a moderate level of UA (300 μM) increased cell viability and reduced TBARS and glutathione (GSH) content. Compared to the control or to independent high glucose (300 mM) or UA (1,200 μM) treatment, the concurrent treatment of high glucose and high UA significantly increased the TBARS, protein carbonyl contents, and ROS concentration, whereas it decreased the cell viability, superoxide dismutase (SOD) activity, and GSH content. In the presence of high glucose and UA, the nucleic protein expression of nuclear factor erythroid 2-related factor 2 (Nrf2) was decreased and the mRNA levels of the genescat, sod1, sod2, gss, andgclcwere downregulated.Conclusion:In conclusion, acute exposure of high level of glucose induced oxidative damage in the cardiac myocytes of chicken. The present result suggests that an adequate level of uric acid is helpful in alleviating the acute oxidative damage that is induced by high glucose, whereas the inhibition of the Nrf2 pathway by a high level of uric acid may render the cardiac myocytes more vulnerable to suffering from oxidative damage.
RUSSIAN WOOD ARCHITECTURE AS AN EXAMPLE OF HOUSEHOLD BUILDINGS
Authors: Shopina E. , Drobot A. 
Published: December 2020

In terms of state-of-art cultural development the deeper understanding and study of Russian heritage with centuries-old knowledge and skills for a designer and architect becomes important. Object of the study is Russian wooden architecture of household buildings, including storehouses.
Research methodology consists of the following: a challenge problem; review of specialized literature; generalization and interpretation of the term; historical and cultural analysis.
Results of the study: it was found that the specificity of the wooden architecture of the Russian North is authenticity and relation with natural feature of area where the buildings are located.
According to the author’s opinion, understanding of relevance to study the history of Russian people and the knowledge accumulated by them in relation to wooden architecture will greatly affect the further development of the architectural mentality of a modern designer.
Comparison of successful spinal puncture between pendant position and traditional sitting position for cesarean deliveries
Authors: Arshad Qurat ul Ain , Jadoon Humaira , Raza Amna , Furqan Zahid , Shahani Yusra Arshad 
Published: December 2020

Background & objectives: Several positions are used for performing subarachnoid block with varying difficulty of spinal access. Pendant position is known to reduce lumbar lordosis in patients’ especially pregnant patients making spinal access easier. The most ideal position for the easy spinal access is yet to be determined. This study was planned to compare ease of spinal access in pendant position vs. traditional sitting position (TSP) in pregnant females, and to establish the superiority of the former.
Methodology: This randomized controlled trial was conducted in our hospital on 232 subjects over 6 month period. Parturients undergoing elective lower segment cesarean section (LSCS) were randomly divided into two groups: Group A (pendant group) and Group B (TSP group). Spinal puncture was performed at L3-L4 interspace, randomly making one of the two positions. Time for successful spinal, number of needle-to-bone contacts and total number of attempts were recorded.
Results: The median age of the patients was 29 yrs with the interquartile range (IQR) 7. The number of needle-to-bone contacts in Group A was significantly higher compared to Group B (59.48% vs. 33.62%, p = 0.000). Mean time for successful spinal puncture was less in Group A than Group B (17.69 sec vs. 25.54 sec, p = 0.001). The difference in number of attempts for spinal in both positions was not significant.
Conclusion: Pendant position is better than traditional sitting position in achieving successful spinal puncture in terms of needle-to-bone contacts and the time to puncture. However there is no difference in number of attempts for both positions.
Key words: Traditional sitting position; Pendant position; Spinal anesthesia; Cesarean section
Citation: Arshad QUA, Jadoon H, Raza A, Furqan Z, Shahani YA. Comparison of successful spinal puncture between pendant position and traditional sitting position for cesarean deliveries. Anaesth. pain intensive care 2020;24(6):---
Received: 13 July 2020, Reviewed: 28 September 2020, Accepted: 29 September 2020
Brain activity assessment by functional MRI before and after radiofrequency of gasserian ganglia in patients with trigeminal neuralgia
Authors: Abdallah Mohamed , Khalil Sherif , Hamed Ayman , Soliman Radwa K. , Mohamed Abdelraheem 
Published: December 2020

Background and Objectives: Trigeminal neuralgia (TN) is one of the common causes of facial pain. However, its treatment is a challenge. Radiofrequency (RF) is an effective and safe option that is available. In our study, we used functional Magnetic resonance imaging (fMRI) to assess levels of brain activity in patients with TN, before and after receiving radiofrequency.
Methodology: This study is a randomized prospective clinical study. It included 30 patients with TN who were scheduled for thermal (i.e. conventional) radiofrequency (CRF) and pulsed radiofrequency (PRF). 15 patients were randomly assigned to each group. All patients were contacted before the intervention and then 1 week, 1 month, 3 months, and 6 months after the intervention. They were assessed using the Visual Analogue Scale (VAS) score, and their complaints of facial numbness, muscles of mastication dysfunction and carbamazepine dose. fMRI was done before and one month after the intervention.
Results: The study group comprised of 13 men and 17 women; a total of 30 patients. The mean age of patients was 50.60 ±12.06 years in the thermal radiofrequency group and 47.93 ±9.90 years in the pulsed radiofrequency group. The median VAS score before the procedure was 8 in both groups, (7-9) in CRF and (7-8) in PRF. Our study demonstrated a statistically significant difference in VAS score at different stages of follow-up after thermal radiofrequency and pulsed radiofrequency when compared with the pretreatment stage. PRF patients continued on medications. Mild complications as facial numbness and masticatory muscle weakness were reported in the CRF group. In some brain regions, fMRI revealed reduced BOLD signal activation after radiofrequency ablation compared to that before the radiofrequency therapy but it was not significant.
Conclusion: In our study, post-intervention fMRI revealed a reduction in signal activations of some brain regions but we could not correlate these changes with the clinical improvement. Radiofrequency is an effective treatment for trigeminal neuralgia. CRF is preferable as it had less complications.
Key words: fMRI; Trigeminal neuralgia; Pulsed Radiofrequency; Thermal radiofrequency
Citation: Abdallah M, Khalil S, Hamed A, Soliman RK, Mohamed A. Brain activity assessment by functional MRI before and after radiofrequency of gasserian ganglia in patients with trigeminal neuralgia. Anaesth. pain intensive care 2020;24(6):---
Received: 30 July 2020, Reviewed: 6 October 2020, Revised: 29 October 2020, Accepted: 30 October 2020
Abbreviations: fMRI – functional Magnetic Resonance Imaging, RF – Radiofrequency, CRF – Conventional Radiofrequency, PRF – Pulsed Radiofrequency, TN – Trigeminal Neuralgia, BMI – Body mass index, VAS – Visual Analogue Scale, BOLD – Blood Oxygen Level-Dependent, ReHo – Regional Homogeneity, ALFF – Amplitude of Low Frequency fluctuations.
Assessing the completeness of perioperative anesthetic record documentation in a tertiary hospital
Authors: Bolhan Hayatul Akma , Yahya Nurlia , Izaham Azarinah , Wan Mat Wan Rahiza , Abdul Rahman Raha , Musthafa Qurratu Aini 
Published: December 2020

Background and Objective: Many previous studies assessing the completeness of perioperative documentation of surgical patients were reported to be inadequate and unsatisfactory. The aim of this study was to compare the perioperative anesthetic record (PAR) at our tertiary care institution to a standard guideline and have an audit of its completeness.
Methodology: It was a prospective, observational study, done in the general operating theater of Universiti Kebangsaan Malaysia Medical Centre (UKMMC). We compared our PAR to the American Society of Anesthesiologists (ASA) policy statement on documentation of anesthesia care. We audited the completeness of PAR documentation of 358 patients by using a self-generated checklist which was created in accordance to the PAR parameters. A total of 44 parameters were studied covering three phases; preoperative, peroperative and post-operative phases.
Results: Although the UKMMC PAR varied from the ASA guidelines, various salient parameters were identical in both. None of the perioperative forms were completely filled throughout the three perioperative phases. Out of 44 parameters studied, only 2 parameters were completely filled, which were medications administered and fluid therapy.
Conclusion: Parameters given in the UKMMC PAR varied with the ASA guidelines and the documentation was found to be only partially complete. Hence, necessary modification of the current PAR in our institution, and the stress on filling it completely is needed to improve the quality of perioperative anesthetic documentation.
Keywords: Audit; Completeness; Perioperative; Anesthetic record; Documentation
Citation: Bolhan HA, Yahya N, Izaham A, Mat WRW, Rahman RA, Musthafa QA. Anaesth. pain intensive care 2020;24(6):---
Received: 23 April 2020, Reviewed: 17 August 2020, Revised: 18 October 2020, Accepted: 27 October 2020
Selecting the ideal adjuvant to improve neuraxial and regional analgesia: A narrative review
Authors: Dmytro Dmytriiev , Oleksandr Nazarchuk , Kostiantyn Dmytriiev , Evgenii Lysak , Olesya Zaletska 
Published: December 2020

Introduction: The aim of this review was to systematize known facts about the effects of adjuvants to local anesthetics for neuraxial and regional analgesia in order to determine the adjuvant with the best effect among all others. More precisely to consider the time to onset, the strength of the effect, duration of the motor and sensory block and some additional effects such as ‘marker of intravascular injection’, safety and toxicity profile. We aimed to find an ideal adjuvant which has all these properties to a good degree.
Methodology: For this narrative review we searched the information in Medline, PubMed, Scopus, and Embase databases. 105 articles were identified regarding the topic, published since 1989 to 2020. Data from 105 articles about adjuvants to local anesthetics was analyzed and synthesized in this review.
Results: Regional methods of analgesia are becoming a crucial part of anesthesiologists’ practice and the knowledge about adjuvants is developing alongside with it, so there are more and more studies devoted to it. All of them try to find the “ideal” adjuvant, having sufficient necessary effects, but we think that due to the difference in various classes of adjuvants, some may be better than others. However, use of combination of adjuvants is not desirable at all times.
Conclusion: A variety of adjuvants to local anesthetics are available now, yet the data about most of them remains inconclusive, so more studies are required to found out the best adjuvants with the most desirable profile and the least adverse effects
Key words: Local anesthetic; Adjuvants; Pain management; Regional anesthesia.
Citation: Dmytro D, Oleksandr N, Kostiantyn D, Evgenii L, Olesya Z. Selecting the ideal adjuvant to improve neuraxial and regional analgesia: A narrative review. Anaesth. pain intensive care 2020;24(6):---; DOI: 10.35975/apic.v24i6.1209
Received: 24 March 2020, Reviewed: 23 April, 25 June 2020, Revised: 18 October 2020, Accepted: 27 October 2020
ACTIVITY OF Annona Squamosa PEELS EXTRACTS AGAINST TWO PATHOGENIC BACTERIA AND TWO BLOOD CANCER CELL LINES
Authors: & et al. Altaee 
Published: December 2020

This research project was designed to assess the antibacterial and antitcancer activity by using the crude extracts of fresh and dried peels of Annona squamosa fruit. The fresh and dried peels were extracted by using three solvents, inculded (water, ethanol, and methanol) at different concentrations (stock, 50, 25, 12.5, 6.25) µg/ml. The antibacterial activity was estimated against Gram-positive bacteria (Staphylococcus aureus) and Gram - negative bacteria (Pseudomonas aeruginosa) using agar well-diffusion method. Results showed the appearance of different regions of inhibition. Antibacterial activity of alcoholic solvent extracts of the dry and fresh peels showed noticeable inhibitory activity against both tested bacteria when comparing the last one with the aqueous extract of peels. The results of anticancer activity estimation against two hematological blood cancer cell lines showed that the three solvents for fresh and dried peels caused a remarkable inhibitory effects and the ethanolic extracts of dried peels was the best. This encourage for the possibility of using peels extracts of Annona. squamosa as a natural resources for growth inhibiting of different types of bacteria and cancer cells.
KEMAMPUAN SPASIAL SISWA MELALUI MODEL PEMBELAJARAN BERBASIS MASALAH BERBANTUAN ALAT PERAGA BERBAHAN PIPET
Authors: Usman Andriyani , Fauzi Amin , Karnasih Ida , Mujib Abdul 
Published: December 2020

Tujuan dari penelitian ini untuk mengetahui apakah peningkatan kemampuan spasial matematis siswa menggunakan model pembelajaran berbasis masalah berbantuan Alat peraga lebih tinggi daripada kemampuan spasial siswa yang diajarkan dengan model pembelajaran konvensional. Penelitian ini dilaksanakan pada siswa kelas VIII SMP Swasta Al Ulum Medan yang berjumlah 30 siswa. Jenis penelitian ini adalah quasi eksperimen (eksperimen semu) dengan desain penelitian pre-test-post-tes control group design. Populasi dalam penelitian ini adalah seluruh siswa kelas VIII SMP Swasta Al ulum Medan tahun ajaran 2019/2020 dengan mengambil sampel dua kelas (eksperimen dan kontrol) melalui teknik random sampling yang mana pada masing-masing kelas terdiri dari 15 siswa. Instrumen yang digunakan dalam pengumpulan data terdiri dari tes kemampuan spasial. Data dianalisis dengan menggunakan uji ANAVA dua jalur. Hasil penelitian menunjukan peningkatan kemampuan spasial matematis siswa menggunakan model pembelajaran berbasis masalah berbantuan alat peraga lebih tinggi daripada kemampuan spaisal siswa yang diajarkan dengan model pembelajaran konvensional.
Strategic benchmarks in public regulation of the domestic consumer goods market
Authors: Popadynets Nazariy , Irtyshcheva Inna , Kramarenko Iryna , Danylo Svitlana , Zhuravel Yuliya 
Published: December 2020

Nowadays, the domestic consumer goods market plays an important role in maintaining the living standards of the population. Its development is an important precondition of accelerated economic growth in the country. Yet, the current condition of the domestic market is characterized by the availability of many negative trends that are stipulated by the bottlenecks in the public regulation of the consumer market and lack of controllability of its certain development processes. An objective need to search for the ways and tools to efficiently manage the development of the domestic consumer market on the system basis requires the thorough scientific-methodological substantiation of a range of important issues like defining the goals and priorities of the consumer market development and elaborating the tactics of its development in times of European integration as a set of measures directed at the implementation of strategic goals. The paper aims to determine the strategic priorities in public regulation of the domestic consumer goods market. The paper examines the theoretical foundations of the consumer market’s public regulation. The functioning of enterprises on the domestic market is analyzed, and on this basis, their operating efficiency is determined. The regulative framework related to the issues of the economic development and trade processes in particular in the times of COVID-19 is analyzed. The priorities and tasks of regulation of the competitive process at the domestic market in the short-term and middle-term perspectives in conditions of the pandemic are suggested based on examining the foreign sector of Ukraine in 2013-2019 and the consensus-prognosis for 2020-2021. The place of the domestic consumer goods market’s development strategy in maintaining the sustainable development in Ukraine is determined, and the main tasks of implementation of the domestic consumer goods market’s development policy are outlined. In the course of examining the main trends of the domestic market functioning in current economic conditions, the problems hampering their development were identified. The strategy of the domestic consumer goods market development is characterized.
The Impact of Quantum Mechanics on the Old Paradigm of Physics
Authors: Wei Xueheng 
Published: December 2020

Quantum mechanics is more creativity than relativity theory. How does quantum mechanics impact the paradigm of classical physics? Although both Einstein and Bohr raised relatively vague questions about the old paradigm of physics, such as Einstein's question about differential equations and Bohr's use of "blind crutches" to question the cognitive function of experimental instruments. But there has been no outright skepticism.