bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Umbelliprenin on Antinociceptive Activity of Morphine in a Rat Model of Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve
Authors: Nazemi Samad , Jafari Faranak , Amin Bahareh , Gholami Omid , Kafami Marzieh , Mojadadi Mohammad-Shafi 
Published: April 2020

Objective:
Although morphine is among of the first line medicines for treatment of neuropathic pain, evidence has shown that the morphine efficacy gradually decreases and a tolerance can occur. Rregarding the many reports concerning the antinociceptive and anti-inflammatory properties of umbelliprenin (UMB), this study aimed to investigate the effect of UMB on antinociceptive activity of morphine in a rat model of neuropathic pain induced by chronic constriction injury (CCI) of the sciatic nerve.

Methods:
Twenty-four male Wistar rats were randomly divided into sham, CCI and CCI + UMB100
(100 μg UMB per rat) groups. UMB was intrathecally administered once daily for four consecutive
days (from the day before surgery until day 2 after surgery). All the animals received a single dose
of morphine (5 mg/kg, s.c.) on day 14. To evaluate the effect of UMB on antinociceptive activity of
morphine, allodynia and hyperalgesia were measured using the von-Frey and hot plate tests, before
and 30 min after morphine injection and the Percentage of Maximum Possible Effect (%MPE) was
calculated. Besides, the expression and concentration of tumor necrosis factor-alpha (TNF-α), as a
proinflammatory cytokine, was measured in the spinal cord using quantitative real-time PCR (RTPCR)
and ELISA, respectively.

Results:
UMB significantly enhanced anti-allodynic and anti-hyperalgesic effects of morphine in the
neuropathic animals. Moreover, UMB considerably downregulated TNF-α expression in the spinal
cord of the animals.

Conclusion:
UMB can enhance the antinociceptive effects of morphine, and this action may be partially
due to its anti-inflammatory property.
Analysis on the Penetration Level of Wind Farm Considering Transient Stability Constraint and Uncertainty of Wind Power
Authors: Hao Bai , Andi Huang , Changcheng Zhou 
Published: April 2020

Background:
The penetration level of a wind farm with transient stability constraint and
static security constraint has been a key problem in wind power applications.

Objective:
The study explores maximum penetration level problem of wind considering transient
stability constraint and uncertainty of wind power out, based on credibility theory and corrected
energy function method.

Methods:
According to the corrected energy function, the transient stability constraint of the power
grid is transferred to the penetration level problem of a wind farm. Wind speed forecast error is
handled as a fuzzy variable to express the uncertainty of wind farm output. Then this paper builds a
fuzzy chance-constrained model to calculate wind farm penetration level. To avoid inefficient
fuzzy simulation, the model is simplified to a mixed integer linear programming model.

Results:
The results validate the proposed model and investigate the influence of grid-connection
node, wind turbine characteristic, fuzzy reliability index, and transient stability index on wind farm
penetration level.

Conclusion:
The result shows that the model proposed in this study can consider the uncertainty of
wind power out and establish a quantitative transient stability constraint to determine the wind farm
penetration level with a certain fuzzy confidence level.
Hubungan kemampuan koneksi matematika, rasa ingin tahu dan self-efficacy dengan kemampuan penalaran matematika
Authors: Hadiat Hanifah Latifah , Karyati Karyati 
Published: April 2020

Penelitian ini bertujuan untuk mendeskripsikan hubungan kemampuan koneksi matematika, rasa ingin tahu, dan self-efficacy dengan kemampuan penalaran matematis siswa SMA. Penelitian ini merupakan penelitian kuantitatif dengan jenis penelitian ex post facto. Populasi penelitian mencakup seluruh siswa kelas X di Kabupaten Brebes. Sampel adalah 362 siswa yang berasal dari enam sekolah di Kabupaten Brebes ditentukan dengan stratified propotional random sampling technique. Pengumpulan data dilakukan menggunakan tes dan angket dengan skala likert. Teknik analisis data yang digunakan adalah analisis linier ganda dan analisis korelasi parsial. Hasil penelitian menunjukkan bahwa kemampuan koneksi matematis, rasa ingin tahu, dan self-efficacy secara bersama-sama berhubungan dengan kemampuan penalaran matematika siswa SMA, dimana kontribusi yang diberikan sebesar 46,3%, serta persamaan regresi yang diperoleh yaitu Y = 0,97 + 0,422X1 + 0,059 X2 + 0,041 X3. Hubungan antara kemampuan koneksi matematis (X1) dengan kemampuan penalaran (Y) dengan kontribusi sebesar 23,27%. Hubungan antara rasa ingin tahu (X2) dengan kemampuan penalaran dengan kontribusi sebesar 3,59%. Hubungan antara self-efficacy (X3) dengan kemampuan penalaran dengan kontribusi sebesar 1,81%. Relationship between mathematical connection ability, curiosity, and self-efficacy with mathematical reasoning abilityAbstractThis study aimed to describe the relationship between mathematical connection ability, curiosity, and self-efficacy and the mathematical reasoning ability of senior high school students. This study was a quantitative ex post facto study. The population comprised all tenth-grade students of senior high school in Brebes District, Indonesia. The sample was 362 students from six schools that were established using the stratified proportional random sampling technique. The data were collected through a test and Likert-scale questionnaires. The data were analyzed using multiple regression and partial correlation analysis. The results showed that mathematical connection ability, curiosity, and self-efficacy, as an aggregate correlated with mathematical reasoning ability, with a contribution of 46,3% obtained by the regression model Y = 0.97 + 0.422X1 + 0.059 X2 + 0.041 X3. The relationship between mathematical connection and mathematical reasoning ability with the contribution of 23.27%. The relationship between curiosity and mathematical reasoning ability with the contribution of 3.59%. The relationship between self-efficacy and mathematical reasoning ability with the contribution of 1.81%.
Temporal Dynamics of Treatment Receipt in a Text Message Intervention for Physical Activity: Single-Group, Within-Person Trial
Authors: Conroy David E , Yang Chih-Hsiang , Lanza Stephanie T , Smyth Joshua M , Lagoa Constantino M 
Published: April 2020

Background
Mobile technology has increased the reach of health behavior interventions but raised new challenges in assessing the fidelity of treatment receipt. Fidelity can be compromised if participant fatigue or burden reduces engagement, leading to missed or delayed treatments for just-in-time interventions.

Objective
This study aimed to investigate the temporal dynamics of text message receipt confirmations.

Methods
Community-dwelling adults (N=10) were sent five text messages daily for 4 months (5598 messages sent in total), with a financial incentive to confirm receipt of 75% or more messages.

Results
Overall, the message receipt confirmation rate was very high (5504/5598, 98.32%) and timely (eg, two-thirds of confirmations within 2 min). Confirmation times were slightly slower on weekends (vs weekdays) and as a function of the cumulative time in the study. Neither time of message delivery nor message content was associated with message confirmation latencies.

Conclusions
Participants receiving financial incentives to confirm text message receipt exhibit extremely high and fast confirmation rates, although receipt confirmations were somewhat less timely on weekends (vs weekdays) and later in the intervention. The social calendar and treatment fatigue should be considered when planning text message–based interventions, especially if treatments are intended for a just-in-time delivery that requires extended engagement and precise timing.
Usability of a Consumer Health Informatics Tool Following Completion of a Clinical Trial: Focus Group Study
Authors: Cho Hwayoung , Porras Tiffany , Flynn Gabriella , Schnall Rebecca 
Published: April 2020

Background
Mobile health (mHealth) apps have the potential to be effective tools for encouraging patients with chronic diseases to self-manage their health. The success of mHealth apps is related to technology acceptance and its subsequent use by intended consumers. Therefore, it is essential to gain insights from consumers’ perspectives about their use of mHealth apps in daily life.

Objective
The purpose of this work was to understand consumers’ perspectives on use of a self-management app following completion of a clinical trial that tested the efficacy of the app for improving health outcomes.

Methods
We conducted five focus groups with paricipants of a clinical trial (NCT03182738) who were randomized to use the video information provider (VIP) for HIV-associated nonAIDS (HANA) conditions app (VIP-HANA) or an attention control app. Thematic analysis was conducted, and the themes were organized according to the two key constructs of the technology acceptance model framework: perceived usefulness and perceived ease of use.

Results
Thirty-nine people living with HIV (20 from the intervention group and 19 from the control group) participated in the focus group sessions. Of the eight themes identified from focus group data, the five themes related to perceived usefulness were: (1) self-monitoring HIV-related symptoms of HANA conditions, (2) enhanced relationship with clinical providers, (3) improvement in physical and emotional health, (4) long-term impact of self-care strategies on improvement in symptoms of HANA conditions, and (5) inspired lifestyle changes to manage symptoms. The three themes related to perceived ease of use were: (1) easy to navigate, (2) avatar personalization, and (3) privacy/confidentiality maintained even when changing the location of app use.

Conclusions
Perceived ease of use was similar in both study groups but perceived usefulness differed between study groups. Participants in both study groups found the VIP-HANA app to be useful in monitoring their symptoms and enhancing communication with their clinical care providers. However, only intervention group participants perceived the app to be useful in improving overall health and long-term symptom management. Findings from this study highlight factors that are essential to ensure the usefulness of self-management apps and facilitate sustained use of mHealth apps for people living with chronic illnesses.
Kejadian Infeksi Menular Seksual di Kota Denpasar Tahun 2016
Authors: Widyanthini Desak , Kurniasari Ni Made Dian , Widyanthari Desak Made 
Published: April 2020

Abstract
The incidence of sexually transmitted infections (STI) that occurred in Denpasar since 2010 until the year 2012 has increased. This study aims to provide an illustration of the incidence of STIs in Denpasar City in 2016 and its influencing factors. This was an analytical study of data derived from medical records of patients who performed STI examination at four public health centers (puskesmas) in Denpasar City from January to December 2016. Data were assessed by univariate and bivariate analyses using chi-square test. The results showed that from a total of 1,397 respondents, 18.2% were diagnosed as STI positives. The result of bivariate analysis showed that the significant factors for the incidence of STI were female sex worker’s customers (OR=2.3 95% CI: 1.7-3.2; p<0.001), employed respondents (OR=2.2; 95% CI: 1.7-2.9; p<0.001), male (OR=1.6; 95% CI: 1.2-2.1; p=0.001) and married (OR=1.4; 95% CI: 1.1-1.9; p=0.014). It is recommended that each puskesmas should conduct community outreach activities especially to female sex worker’s customers as one of groups with high risk of STI infections.
Keywords: Sexually transmitted infections, public health centers, Denpasar
Abstrak
Sejak tahun 2010 sampai dengan tahun 2012 insiden Infeksi menular seksual (IMS) di Kota Denpasar mengalami peningkatan. Penelitian ini bertujuan untuk memberikan gambaran kejadian IMS di Kota Denpasar tahun 2016 dan faktor-faktor yang mempengaruhinya. Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional menggunakan data rekam medis pasien yang melakukan pemeriksaan IMS (data tercatat pada SIHA IMS) periode Januari sampai dengan Desember 2016 di empat puskesmas di Kota Denpasar. Analisis dilakukan secara univariat dan bivariate dengan chi square test. Penelitian ini menunjukkan bahwa dari total 1397 reponden, sebanyak 18,2% didiagnosis positif IMS). Hasil analisa bivariat menunjukkan faktor yang signifikan terhadap kejadian IMS adalah responden pelanggan PSK (OR=2,3 95% CI: 1,7- 3,2; p<0,001), bekerja (OR=2,2; 95% CI: 1,7-2,9; p<0,001 ), laki-laki (OR=1,6; 95% CI: 1,2-2,1; p=0,001) dan sudah menikah (OR=1,4; 95% CI: 1,1-1,9; p=0.014). Diharapkan pada masingmasing puskesmas agar kegiatan penjangkauan yang selama ini ada dapat menyasar pelanggan PSK sebagai salah satu kelompok dengan risiko IMS.
Kata kunci: Infeksi menular seksual, puskesmas, Denpasar
Determinan Paparan Asap Rokok di Dalam Rumah
Authors: Herawati Pipit , Wahyudi Kurnia , Afriandi Irvan 
Published: April 2020

Abstract
Indonesia has become the 3rd country with the highest smokers in the world after China and India. Most of the smokers were smoking inside the house. This study was aimed at investigating the prevalence of cigarette smoke exposures inside the house based on provinces and its family’s socio-economy factors. It was a logistic regression based on secondary data from Indonesia Demographic Health Survey (IDHS) 2012 with a total sample of 30,942. The study showed nationally that the prevalence of cigarette smoking reached 80%. The highest was Gorontalo Province and the lowest was DKI Jakarta Province. Sex of the head of household and their education attainment found as the strongest predictor of smoke exposures. There is a need for targeted intervention especially for the province with the highest prevalence, low educated people, poorer, existence of toodlers, informal workers, and lives at rural areas in Indonesia.
Keywords : Cigarette, IDHS, indoor air pollution, Indonesia, SHS, Environmental Health.
Abstrak
Indonesia menjadi negara ketiga dengan prevalensi perokok tertinggi di dunia setelah Cina dan India. Para perokok sebagian besar merokok di dalam rumah. Penelitian bertujuan untuk mengetahui prevalensi paparan asap rokok dalam rumah berdasarkan provinsi dan faktor sosio ekonomi rumah tangga dengan paparan asap rokok di dalam rumah. Ini adalah analisis regresi logistic menggunakan data sekunder Survei Demografi dan Kesehatan Indonesia (SDKI) 2012 dengan jumlah sampel 30.942 dianalisis dengan regresi logistik. Secara nasional prevalensi paparan asap rokok mencapai 80%. Prevalensi tertinggi di provinsi Gorontalo dan terendah di provinsi DKI Jakarta. Jenis kelamin kepala keluarga dan pendidikan kepala keluarga merupakan prediktor terkuat paparan asap rokok dalam rumah. Diperlukan suatu intervensi terarah terutama di wilayah dengan prevalensi paparan asap rokok tinggi, menargetkan kelompok masyarakat pendidikan rendah, miskin, memiliki balita, kerja sektor informal dan tinggal di wilayah perdesaan di Indonesia.
Kata kunci: Indonesia, kesehatan lingkungan, polusi udara di dalam ruangan, rokok, SDKI.
Identificación de microbiota bucal en caninos en estado de abandono
Authors: Corrales Lucia Constanza , Antolinez Romero Diana Marcela , Bohórquez Macías Johanna Azucena , Corredor Vargas Aura Marcela 
Published: April 2020

Objetivo. Describir la microbiota que se encuentra en la cavidad bucal de caninos en condición de abandono de la Fundación Razas Únicas en el municipio de Chía – Cundinamarca. Métodos. Para el estudio se tomaron 29 muestras orales con escobillón a 23 caninos de la Fundación Razas Únicas del municipio de Chía – Cundinamarca. 23 muestras se recolectaron para identificación de bacterias aerobias y anaerobias facultativas, las cuales se transportaron en medio líquido tripticasa soya y 6 muestras para recuperación de bacterias anaerobias estrictas transportadas en medio VMGA-III. El aislamiento de los microorganismos se realizó en medios selectivos y la identificación con el sistema BD BBL™Crystal™. Resultados. De las 29 muestras analizadas se aislaron 59 bacterias, entre ellas 15 géneros y 15 especies diferentes como; Escherichia coli, Proteus mirabilis, Citrobacter freundii, Enterobacter sakazakii, Enterobacter cloacae, Enterococcus durans, Enterococcus faecalis, Eikenella corrodens, Porphyromonas endodontalis, Fusobacterium spp y Capnocytophaga spp. De acuerdo con la revisión de la literatura, las bacterias anaerobias encontradas están principalmente relacionadas con enfermedad periodontal y las enterobacterias con contaminación oro-fecal.
Does Mandatory Retrospective Hedge Effectiveness Assessment under ASC 815 Provide Risk-Relevant Information?
Authors: Chen Zhihong , Liu Alfred Zhu , Seow Gim S. , Xie Hong 
Published: April 2020

SYNOPSIS
Current accounting standards permit special accounting treatment of derivatives used for hedging purposes. However, the requirement to perform periodic, retrospective assessments of hedge effectiveness and to disclose a quantitative accounting measure of hedge ineffectiveness (AMHI) for such derivatives has been controversial. In response to concerns over the compliance costs of this requirement, the FASB removed this requirement in the recently effective ASU 2017-12. However, this change was made with little empirical evidence on the benefits of retrospective effectiveness assessment and quantitative disclosure of AMHI. We document one potential benefit of this requirement to investors by providing initial evidence that (1) AMHI is positively associated with an array of concurrent market- and accounting-based risk measures and (2) investors react negatively to large AMHIs and related disclosures upon 10-K filings. Our findings suggest that this requirement can provide investors with risk-relevant information and shed light on its potential usefulness.
Abnormal Audit Fees and Audit Quality: Evidence from the Korean Audit Market
Authors: Behrend Matthew J. , Khan Sarfraz , Ko Young Woo , Park Sung-Jin 
Published: April 2020

ABSTRACT
Do abnormally high or low audit fees reflect audit quality? In this paper, we re-examine this issue after controlling for the confounding effect of audit hours by using a sample of public firms in the Korean audit market, which publicly discloses both audit fees and audit hour information. While we do not find a significant association between abnormally high audit fees and audit quality, we find that abnormally low audit fees are associated with larger discretionary accruals and a higher likelihood of meeting or beating analyst earnings forecasts. Further, we find that the relationship between abnormally low audit fees and audit quality indicators persists regardless of the level of audit hours. To the extent that audit hours represent audit effort, these findings suggest that greater audit effort alone may not lead to higher audit quality as fee pressure from abnormally low fees may discourage the provision of high-quality audit services.
JEL Classifications: M42; M48.
A formação do gestor educacional e os desafios da atuação profissional
Authors: Santos Gladmir da Veiga , Keller-Franco Elize 
Published: April 2020

Este estudo objetiva analisar a formação dos gestores escolares e as principais necessidades formativas para o enfrentamento dos desafios da profissão. A pesquisa define-se como exploratória-descritiva. Como campo empírico, selecionou-se uma rede particular de ensino do estado de São Paulo. Os dados foram obtidos mediante um questionário online elaborado com o apoio da plataforma Survio. Os dados da realidade pesquisada revelam alguns desafios relacionados à formação dos gestores, tais como a insatisfação com a graduação; diretores que assumem a profissão sem experiência prévia ou ainda, com formação fora da área educacional; predomínio da concepção técnico-científica de gestão; dentre outros, sinalizando para dois direcionamentos importantes: o investimento em programas de formação para gestores iniciantes e programas para o desenvolvimento contínuo ao longo da carreira. Ressalta-se a importância de novas pesquisas que possibilitem ampliar o entendimento e os olhares para a formação dos gestores.
Description of selected pneumatic elements and systems using fractional calculus
Authors: Pietruszczak Daniel , Nowocień Artur 
Published: April 2020

The paper presents the application of fractional calculus to describe the dynamics of selected pneumatic elements and systems. In the construction of mathematical models of the analysed dynamic systems, the Riemann-Liouville definition of differintegral of non- integer order was used. For the analysed model, transfer function of integer and non-integer order was determined. Functions describing characteristics in frequency domains were determined, whereas the characteristics of the elements and systems were obtained by means of computer simulation. MATLAB programme were used for the simulation research.
Managerial Factors in Investment Risk: Evidence from Polish Mutual Funds
Authors: Filip Dariusz 
Published: April 2020

Abstract
The aim of this study is to examine whether investment risk is related to the managerial factors characterising portfolio managers. The study employs four risk measures and a set of individual manager characteristics, including socio-demographic variables determining a manager profile. The analysis is conducted based on data for 144 portfolio managers from 43 domestic equity funds operating in Poland in the period 2000-2015. The examinations are made possible by using static panel models. The obtained results indicate the existence of a relationship between managerial characteristics and risk measures, such as: standard deviation, beta coefficient, tracking error and bear-market percentile ranking. To our knowledge, it is the first paper to evaluate the investment risk of Polish mutual funds in relation to managerial characteristics.
Assessment of Hydrogeological Potential and Aquifer Protective Capacity of Odeda, Southwestern Nigeria
Authors: Aina J.O. , Adeleke O.O. , Makinde V. , Egunjobi H.A. , Biere P.E. 
Published: April 2020

Abstract
Hydrogeological assessment of groundwater resources was carried out with a view to evaluate the potential of the aquifers to provide portable water supply and access the distribution of electrical parameters of hydrogeologic units in some areas in Odeda, Ogun State, Nigeria. A geophysical survey using vertical electrical sounding (VES) with the Schlumberger electrode array, with half-current electrode spacing (AB/2) varying from 1 to 132 m was carried out at 30 different stations in the study area. The VES data were interpreted qualitatively and quantitatively. Three-to-five sub-surface layers consisting of topsoil, weathered layer consisting of clay, sandy clay, clayey sand and sand layers, and fractured/fresh basement were delineated. Layer resistivities and thicknesses obtained on the curves within the study area showed one main aquifer type, which is the fractured basement. The longitudinal unit conductance (ranging from 0.049720 to 1.4520000 mhos) of the study area aided the protective capacity to be rated into good, moderate and weak. About 33% of the study area falls within the weak protective capacity, 57% falls within the moderate protective capacity and 10% falls within the good protective capacity.