bluuebunny/crossref_metadata_2025_split huggingface dataset:
Failure Investigation of a Locomotive Turbocharger Main Shaft and Bearing Sleeve
Authors: Yu Zhiwei , Xu Xiaolei , Guo Xiaoyan 
Published: January 2020

Abstract
The main shaft in a locomotive turbocharger fractured along with an associated bearing sleeve. Visual and fractographic examination revealed that the shaft fractured at a sharp-edged groove between two journals of different cross-sectional area. The dominant failure mechanism was low-cycle rotation-bending fatigue. The bearing sleeve failed as a result of abrasive and adhesive wear. Detailed metallurgical analysis indicated that the sleeve and its respective journal had been subjected to abnormally high temperatures, increasing the amount of friction between the sleeve, bearing bush, and journal surface. The excessive heat also softened the induction-hardened case on the journal surface, decreasing its fatigue strength. Fatigue crack initiation occurred at the root fillet of the groove because of stress concentration.
Investigation on Bulging of Blow Pipe in a Blast Furnace
Authors: Sinha Pankhuri , Mukhopadhyay Goutam , Bhattacharyya Sandip 
Published: January 2020

Abstract
After about a year of uninterrupted service, one of the blow pipes on a blast furnace developed a bulge measuring 300 x 150 x 12 mm. The conical shaped section was removed from the furnace and examined to determine why it failed. The investigation consisted of visual inspection, chemical analysis, microstructural characterization, and mechanical property testing. The pipe was made from nonresulfurized carbon steel as specified and was lined with an alumina refractory. Visual inspection revealed cracks in the refractory lining, which corresponded with the location of the bulge. Microstructural and EDS analysis yielded evidence of overheating, revealing voids, scale, grain boundary oxidation, decarburization, and grain coarsening on the inner surface of the pipe, which also suggest the initiation of creep. Based on the information gathered during the investigation, the blow pipe was exposed to high temperatures when the liner cracked and subsequently bulged out due to creep.
Vaccination against Pneumococcal Infections of High-Risk People: Pharmacoeconomic Aspects
Authors: Rudakova A. V. , Kharit S. M. , Lobzin Yu. V. 
Published: January 2020

Relevance. Vaccination of people at high risk against pneumococcal infection with a 13-valent conjugate vaccine (PCV13) can significantly reduce the corresponding incidence and mortality.The aim of the work was to assess the pharmacoeconomic aspects of vaccination of 65 year olds with a high risk of pneumococcal infection.Material and methods. The analysis was carried out by the method of Markov modeling from the position of the health care system. The time horizon is 5 and 15 years. It was assumed that vaccination is carried out with 1 dose of PCV13 and 1 dose of polysaccharide pneumococcal vaccine (PPV23) after 8 weeks with revaccination with 1 dose of PPV23 after 5 years. The costs of treatment of pneumococcal infections were calculated on the basis of the Compulsory medical insurance rates for St. Petersburg in 2019. The costs of vaccination were calculated on the basis of the price of auctions for the purchase of PCV13 and PPV23 for 2019.Results. For 15 years, vaccination of 100 ths people from the high risk group will prevent 1.7 ths cases of community-acquired pneumonia, 1.4 ths cases of invasive pneumococcal infections, and 397 cases of pneumococcal infections deaths. The cost-effectiveness ratio with a 15-year horizon is 161.4 ths rubles/quality-adjusted life year gained (QALY). Even if the time horizon is reduced to 5 years, vaccination can be considered as an economically highly effective intervention (cost-effectiveness ratio –571.9 ths rubles/QALY). At the same time, in 5 years, 37.6% of the money spent on vaccination will be returned to the budget of the health care system, and in 15 years – 49.3%.Conclusion. Vaccination of citizens of the Russian Federation from a high-risk group against pneumococcal infection can be considered as a socially and economically highly effective intervention that provides a significant reduction in the incidence and mortality caused by it.
Epidemiological Characteristics of perinatal, early neonatal Mortality and Stillbirth in the Territory of the Nizhny Novgorod region
Authors: Sergeeva A. V. , Kovalishena O. V. , Katkova N. Yu. , Polyakova A. A. 
Published: January 2020

Background.The study of regional characteristics of the incidence rates of perinatal mortality, early neonatal mortality, and stillbirths is of undoubted importance, which will allow to substantiate the main directions of improving care for newborns, both at the federal and regional levels.Aims.To study the indicators of perinatal mortality, early neonatal mortality and stillbirths in the territory of the Nizhny Novgorod region in the period from 2012–2016.Materials and methods.Statistical reporting forms of the Ministry of Health of the Nizhny Novgorod region «Basic indicators of public health and the activities of state medical organizations of the Nizhny Novgorod region» for the period from 2012 to 2016. A retrospective descriptive-estimated epidemiological study of perinatal and early neonatal mortality rates and stillbirth rates was conducted. The processing of statistical indicators was carried out by generally accepted methods of variation statistics. The reliability of the indicators was estimated taking into account the confidence interval (2 errors with 95% CI).Results and conclusions.On the territory of the Nizhny Novgorod region in the period from 2012 to 2016. A high level of perinatal mortality and stillbirths was observed compared to the national indicators. The average annual rates of perinatal mortality and stillbirth were significantly higher in Diveevsky and Sokolsky districts compared with the rest of the Nizhny Novgorod region. The risk areas for neonatal mortality include Lukoyanovsky and Tonkin. It is necessary to improve the quality of medical care for pregnant women at all stages, including prenatal and, of course, obstetric care. An important role here is played by the improvement of the epidemiological surveillance system, which allows an objective analysis of the current situation and an assessment of the quality of medical care.
Extension du domaine de l’entrepreneurialité dans la pratique du vide-dressing
Authors: Juge Élodie , Collin-Lachaud Isabelle , Roux Dominique 
Published: January 2020

Cette recherche éclaire la manière dont les nouveaux dispositifs sociotechniques (plateformes, applications mobiles, etc.) remodèlent les échanges, tissent de nouvelles relations avec leurs usagers, transforment les rapports humains et modifient le rôle du consommateur dans la pratique du vide-dressing. Mobilisant une approche qualitative multi-méthode sur une période de six années, cette recherche révèle à la fois les dimensions entrepreneuriales de la pratique et la « post-socialité » qu’elle participe à construire.
Valoriser la recherche par l’expérimentation en entreprise
Authors: Savall Henri , Zardet Véronique , Bonnet Marc , Cappelletti Laurent 
Published: January 2020

Pour apporter des réponses à la question de la valorisation managériale des recherches en gestion, l’article explore l’exemple du modèle de management socio-économique. En effet, ce modèle expérimenté dans 2 000 organisations depuis 1974 a précisément pour objet, au moyen de la méthode scientifique dénommée recherche-intervention qualimétrique, de fabriquer des produits d’intention scientifique socialement utiles aux entreprises et aux organisations. L’article décrypte les principes théoriques et épistémologiques de ce modèle, son processus, la méthode de recherche-intervention employée et des résultats significatifs de valorisation de la recherche.
Cost-effectiveness of postoperative rehabilitation after surgery for lumbar disc herniation: an analysis based on a randomized controlled trial
Authors: Paulsen Rune T. , Sørensen Jan , Carreon Leah Y. , Andersen Mikkel Ø. 
Published: January 2020

OBJECTIVEThe aim of this study was to examine whether routine referral to municipal postoperative rehabilitation is cost-effective in comparison to no referral after surgery for lumbar disc herniation (LDH).METHODSOne hundred forty-six patients scheduled for primary discectomy due to LDH were included. This secondary analysis, based on data from a previous randomized controlled trial, compared costs and quality-adjusted life years (QALYs) between two groups of patients recovering from LDH surgery: one group of patients received a referral for municipal physical rehabilitation (REHAB) and the other group was sent home without a referral to any postoperative rehabilitation (HOME). Primary outcomes were QALYs calculated from the EQ-5D utility score, societal costs, and incremental cost-effectiveness ratios (ICERs). The main cost-effectiveness analysis used intention-to-treat data, whereas sensitivity analyses included as-treated data. Questionnaires were collected after 1, 3, 6, 12, and 24 months postoperatively.RESULTSThe main cost-effectiveness analysis showed a small, insignificant incremental QALY of 0.021 and an incremental cost of €211.8 for the REHAB group compared to the HOME group, resulting in an ICER of €10,085. In the as-treated sensitivity analysis, the REHAB group had poorer outcomes and higher costs compared to the HOME group.CONCLUSIONSRoutine referral to municipal physical rehabilitation in patients recovering from LDH surgery was not cost-effective compared to no referral.Clinical trial registration no.: NCT03505918 (clinicaltrials.gov)
MRI-guided cryoablation for metastatic spine disease: intermediate-term clinical outcomes in 14 consecutive patients
Authors: Moses Ziev B. , Lee Thomas C. , Huang Kevin T. , Guenette Jeffrey P. , Chi John H. 
Published: January 2020

OBJECTIVEMinimal access ablative techniques have emerged as a less invasive option for spinal metastatic disease reduction and separation from neural tissue. Compared with heat-based ablation modalities, percutaneous image-guided cryoablation allows for more distinct visualization of treatment margins. The authors report on a series of patients undergoing MRI-guided cryoablation as a feasible method for treating spinal metastatic disease.METHODSA total of 14 patients with metastatic spine disease undergoing MR-monitored cryoablation were prospectively enrolled. Procedures were performed in an advanced imaging operating suite with the use of both CT and MRI to gain access to the spinal canal and monitor real-time cryoablation.RESULTSThe average age was 54.5 years (range 35–81 years). The mean preoperative Karnofsky Performance Status score was 79.3 (range 35–90). The average radiographic follow-up was 7.1 months (range 25–772 days), and the average clinical follow-up was 9.8 months (range 7–943 days). In 10 patients with epidural disease, 7 patients underwent postprocedural imaging, and of these 71% (5/7) had stable or reduced radiographic disease burden. Bone regrowth was observed in 63% (5/8) of patients with bone ablation during the treatment who had postoperative imaging. Pre- and postoperative visual analog scale scores were obtained, and a significant reduction in these scores was found following ablation. There were no complications.CONCLUSIONSMR-guided cryoablation is a minimally invasive treatment option for metastatic spine disease. In patients with epidural disease, the majority experienced tumor reduction or arrest at follow-up. In addition, pain was significantly improved following ablation. The average hospital stay was short, and the procedure was safe in a range of patients who are otherwise not ideal candidates for standard treatment.
ANALISIS PENERAPAN ETIKA DAN HUKUM KESEHATAN PADA PEMBERIAN PELAYANAN KESEHATAN DI RUMAH SAKIT NENE MALLOMO KABUPATEN SIDENRENG RAPPANG
Authors: Anggie Septie Aningrum AN Anggie Septie Aningrum AN 
Published: January 2020

Dalam pelayanan kesehatan perilaku petugas kesehatan harus tunduk pada etika profesi (kode etik profesi) dan juga tunduk pada ketentun hukum, aturan, dan perundang-undangan.. Penelitian ini merumuskan masalah yaitu bagaimana pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap, bagaimana penerapan etika dalam pemberian pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap, dan bagaimana penerapan hukum kesehatan dalam pemberian pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap. tujuan dari penelitian ini adalah untuk mengetahui pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap, penerapan etika dalam pemberian pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap, dan mengetahui penerapan hukum kesehatan dalam pemberian pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap.
Penelitian ini dengan metode survei deskriptif yang dilakukan di Rumah Sakit Nene Mallomo Kab. Sidrap menggunakan kuesioner yang diberikan ke sampel yaitu 99 pasien rawat inap yang ditentukan dengan teknik Accidental Sampling. Data diolah dengan bantuan aplikasi SPSS 24 dan di analisis secara univariate sehingga menghasilkan frekuensi distribusi setiap variabel.
Berdasarkan analisis data didapatkan bahwa Pelayanan kesehatan yang diberikan di Rumah Sakit Nene Mallomo Kab.Sidrap dalam kategori memuaskan pasien, penerapan etika dalam pemberian pelayanan kesehatan sudah baik dan sesuai dengan aturan kode etika dan, Penerapan hukum kesehatan dalam pemberian pelayanan di Rumah Sakit Nene Mallomo Kab. Sidrap sudah baik dan sesuai dengan aturan perundang-undangan yang berlaku.
PENGARUH PEMBERIAN AIR KELAPA MUDA TERHADAP PENURUNAN TEKANAN DARAH PADA PENDERITA HIPERTENSI DI WILAYAH KERJA PUSKESMAS LANRISANG KABUPATEN PINRANG
Authors: Fandi Andika1 Fandi Andika , Haniarti  , Amir Patintingan  
Published: January 2020

Penyakit hipertensi dapat dikendalikan dengan pengobatan non farmalokogis salah satunya air kelapa muda, karena kandungan kalium yang terdapat dalam air kelapa muda sangat bermanfaat untuk menurunkan tekanan darah sistolik dan diastolik. Tujuan penelitian adalah untuk mengetahui pengaruh pemberian air kelapa muda terhadap penurunan tekanan darah pada penderita hipertensi di Wilayah Kerja Puskesmas Lanrisang Kabupaten Pinrang.Jenis penelitian yang digunakan adalah eksprimen kuasi (quasi ekspriment). Dengan rancangan one group pre test – post test. Variabel independen adalah pemberian air kelapa muda dan variabel dependen adalah penurunan tekanan darah pada penderita hipertensi. Sampelnya sebanyak 52 responden dan teknik sampling yang digunakan adalah accidental sampling. Penelitian ini dilakukan di Wilayah Kerja Puskesmas Lanrisang Kabupaten Pinrang pada Tanggal 25 Maret sampai 30 Juli 2018. Hasil penelitian ini dapat disimpukan bahwa ada pengaruh pemberian air kelapa muda terhadap penurunan tekanan darah pada penderita hipertensi di Wilayah Kerja Puskesmas Lanrisang Kabupaten Pinrang.
PENGARUH SISTEM ANTRIAN DAN PELAYANAN DALAM MENINGKATKAN EFEKTTIFITAS PELAYANAN PASIEN RAWAT JALAN DI PUSKESMAS MADISING NA MARIO KOTA PAREPARE
Authors: Santi Milanda  , Usman  , Darmawan Ukkas  
Published: January 2020

Loket pendaftaran pasien menjadi ujung tombak pelayanan rawat jalan karena merupakan pelayanan pertama dan secara langsung berinteraksi dengan pasien, sehingga dapat memberikan kesan kepada pasien terhadap mutu pelayanan secara umum. pelayanan yang diberikan di loket pendaftaran belum optimal, maka menimbulkan waktu tunggu yang lama kepada pasien, kondisi ini dapat memicu rendahnya kepuasan pasien. Pada masalah ini, aspek cepat dan tepat sangat diperhitungkan dalam penyelenggaraan jasa pelayanan, artinya membiarkan konsumen menunggu tanpa alasan yang jelas akan menyebabkan persepsi yang negatif dalam mutu atau kualitas pelayanan. Rendahnya mutu pelayanan pada suatu puskesmas akan berkaitan dengan citra puskesmas sekaligus penentu terhadap pemanfaatan ulang pelayanannya. Tujuan penelitian adalah untuk mengetahui sistem antrian dan pelayanan dalam meningkatkan efektifitas pelayanan pasien rawat jalan. Metode yang digunakan penelitian survey analitik dengan pendekatan cross sectional study. Teknik pengambilan Accidental Random Sampling dengan jumlah sampel 100 orang yang berobat ke Puskesmas Madising Na Mario Kota Parepare. Hasil penelitian berdasarkan hasil uji statistic dengan menggunakan chi square, maka diperoleh p (value) = 0,03 untuk sistem antrian dan untuk pelayanan diperoleh p (value) = 0,04. Kesimpulan penelitian adalah ada pengaruh sistem antrian dan pelayanan dalam meningkatkan efektifitas pelayanan pasien rawat jalan di Puskesmas Madising Na Mario Kota Parepare
HUBUNGAN DUKUNGAN SOSIAL DENGAN KUALITAS HIDUP ORANG DENGAN HIV/AIDS (ODHA) DI RUMAH SAKIT UMUM LASINRANG KABUPATEN PINRANG
Authors: Rasni Jumliarni  , Usman  , Henni Kumaladewi Hengky  
Published: January 2020

HHIV/AIDS saat ini bukan hanya berupa penyakit menular saja, tetapi menjadi masalah kesehatan masyarakat yang sangat luas. Berdasarkan data dari Dinas Kesehatan Kabupaten Pinrang mengenai jumlah kasus HIV/AIDS dari tahun 2013 sampai dengan 2017 sebanyak 50 kasus. Sedangkan data dari Rumah Sakit Umum Lasinrang Kabupaten Pinrang, diketahui bahwa 22 orang yang rutin mengambil ARV.HIV tidak hanya berdampak pada kesehatan fisik tetapi juga berdampak pada psikologis ODHA karena adanya diskriminasi di masyarakat. Dengan kondisi seperti ini, maka perlunya menciptakan lingkungan yang kondusif yaitu dengan cara meningkatkan dukungan sosial bagi ODHA. Tujuan penelitian ini untuk mengetahui hubungan dukungan keluarga, teman dan petugas kesehatan dengan kualitas hidup Orang dengan HIV/AIDS (ODHA) di Rumah Sakit Umum Lasinrang Kabupaten Pinrang. Metode yang digunakan dalam penelitian ini adalah metode deskriptif korelasi dengan rancangan penelitian Cross Sectional Study.Peneliti mengidentifikasi melalui observasional dengan menggunakan kuesioner pada sampel, dimana sampel dalam penelitian ini sebanyak 22 orang. Data dianalisis secara univariat dan bivariat menggunakan uji statistik Chi Square melalui SPSS Versi 24. Hasil penelitian menunjukkan bahwa ada hubungan dukungan keluarga (p = 0,010), tidak ada hubungan dukungan teman (p = 0,115), dan ada hubungan dukungan petugas kesehatan (p = 0,046) dengan kualitas hidup Orang dengan HIV/AIDS (ODHA) di Rumah Sakit Umum Lasinrang Kabupaten Pinrang. Penelitian ini menyarankan agar teman ODHA meningkatkan pemahaman dan pengetahuan mengenai HIV/AIDS serta lebih menghargai status ODHA
The Association of Post-Stroke Cognitive Impairment and Gut Microbiota and its Corresponding Metabolites
Authors: Liu Yongqiang , Kong Cheng , Gong Li , Zhang Xiaohui , Zhu Yuefei , Wang Haichao , Qu Xiao , Gao Renyuan , Yin Fang , Liu Xueyuan , Qin Huanlong 
Published: January 2020

Background: Post-stroke cognitive impairment (PSCI) is an important factor causing disabilities after acute ischemic stroke (AIS). Emerging evidence suggested that gut microbiota play an important role in cognitive impairment. Objective: This study aimed to explore the association between PSCI and gut microbiota. Method: 65 patients with newly diagnostic AIS finished the fecal collection on admission and cognitive assessment 3 months later in the clinic. Fecal samples were subjected to 16SrRNA gene sequencing and gas chromatography-mass spectrometry analysis. Additionally, we enrolled new 18 AIS patients, whose treatment was supplemented by probiotics, to assess the potential of microbial treatment in PSCI. Results: PSCI patients were characterized by the significantly decreased alpha-diversity, disturbed microbial composition, and corresponding metabolites compared with non-PSCI patients. Increased Fusobacterium and deficiency of microbial metabolized short-chain fatty acids (SCFAs) were significantly associated with PSCI. A model based on gut microbiota and SCFAs could predict 3 months or longer PSCI early and accurately after stroke onset. While traditional probiotic administration had little effect on PSCI, it could ameliorate patients’ mood, including depression and anxiety in the 3 months after stroke. Conclusion: Our study revealed the association between PSCI and gut microbiota and its corresponding metabolites for the first time, suggesting the potential for applying microbiota and its corresponding metabolites to early clinical diagnosis and treatment of PSCI.
Chromogranin A Analysis in the Differential Diagnosis Across Lewy Body Disorders
Authors: Gmitterova Karin , Varges Daniela , Schmitz Matthias , Zafar Saima , Maass Fabian , Lingor Paul , Zerr Inga 
Published: January 2020

Background: Chromogranin A (CgA) is a general marker of gut endocrine cells, which are part of the “gut-brain axis” in Parkinson’s disease (PD). Objective: We analyzed CgA as a marker of synaptic dysfunction to assess its role in the differential diagnosis across different Lewy body disorders. Methods: We analyzed the CgA levels in the cerebrospinal fluid (CSF) and serum from 54 patients covering the spectrum of Lewy body disorders [13 Parkinson’s disease (PD), 17 Parkinson’s disease dementia (PDD), 24 dementia with Lewy bodies (DLB)] and 14 controls using an ELISA. Results: A positive correlation was noted between CSF and serum CgA levels ( ρ= 0.47, 95% CI: 0.24 to 0.65, p < 0.0001). The highest values of CgA in CSF and in serum were measured in DLB and there was a significant difference between DLB and PDD ( p = 0.03 and p = 0.004). The serum levels of CgA in controls achieved lower values compared to DLB ( p = 0.006). There was a gradual increase in serum levels from PD to PDD and DLB. An inverse correlation was seen between the CSF level of CgA and Aβ42 ( ρ  = –0.296, 95% CI: –0.51 to –0.04, p = 0.02). Conclusion: The incorporation of CgA analysis as an additional biomarker may be useful in the diagnostic work-up of Lewy body dementia. CgA analysis may be relevant in distinguishing DLB from PDD patients and presumably early stages of PD. Our data on altered serum levels in DLB pave the way to the development of blood-based parameters for the differential diagnosis, which however needs to be confirmed in a prospective study.
Violência entre Parceiros Íntimos, Gênero e Saúde: a Integralidade, a Interseccionalidade e a Pedagogia Feminista no Acolhimento às Mulheres e na Educação em/na Saúde
Authors: Dantas-Berger Sônia Maria 
Published: January 2020

A partir de breve demarcação e conceituação do problema da violência contra mulheres, sob as perspectivas de gênero, direitos humanos e saúde pública e, da constatação de sua persistente invisibilidade na assistência em saúde, o artigo aponta algumas consequências para a saúde das mulheres, problematiza o modo como profissionais lidam com tal fenômeno social e, sinaliza limites e demandas abarcados no processo de educação em/na saúde frente ao tema da violência entre parceiros íntimos (VPI), apostando-se na potencialidade do diálogo entre os pressupostos feministas e freirianos para o acolhimento das mulheres em situação de violência, orientado pelos princípios da integralidade e da interseccionalidade.