bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating Business Letter Writing Materials Through Peer Teaching Technique To Management Department Students Of Economics Faculty At The Tridinanti University Of Palembang
Authors: RONI RUSMAN 
Published: August 2020

The current study was aimed to find out whether the developing business letter writing materials through peer editing technique were valid, practical and had potential effect for the management students of Faculty of Economics at Tridinanti University of Palembang. Developmental research proposed by Akker i.e analysis, design, evaluation and revision was applied in this study. In the evaluation phase, formative evaluation model proposed by Tressmer was used (i.eself evaluation, expert review, one to one small group and field test). There were 3 students participating in one to one evaluation, 9 students in small group and one class (34 students) i field test. There were also two validators in reviewing the developing business letter writing materials through peer editing technique . One was expert of content and another one was expert in instructional design. The result of experts judgement showed that the product was valid with average score was 89.2 categorized in good validity. The product was practical with average score in one to one evaluation was 84.3 and in small group phase was 86.8. the effectiveness of the product could be seen from the average score of students’achievement in field test. The score was 92.8 meaning that the score was higher than the criterion of minimal mastery (KKM) of developing business letter writing materials through peer editing technique. Therefore, the product had potential effect categorized in very good level.It could be used for the better improvement and contribution in the field of ESP language teaching and learning.
A FORÇA DE TRABALHO DA ENFERMAGEM BRASILEIRA E A PANDEMIA DO COVID-19
Authors: Gonçalves Lúcia Hisako Takase 
Published: August 2020

Nos dias atuais, encontramo-nos atônitos assistindo, no mundo todo e no país, ao desenrolar dessa pandemia do covid-19. E... o que observamos? Quem está na linha de frente cuidando das vítimas do corona vírus, em todos os cantos do Brasil? É a enfermagem, esse corpo de enfermagem representado por enfermeiros, técnicos e auxiliares de enfermagem, sempre atuantes em quaisquer circunstâncias de atendimento dos pacientes, desde unidades de pronto atendimento a hospitais, expostos a toda sorte de riscos decorrentes da precariedade dos serviços de saúde. Destaquem-se aqui as más condições de trabalho dos profissionais da enfermagem, que sequer dispõem dos Equipamentos de Proteção Individual adequados, para o seu mais longo plantão de 8 ou 12 horas diárias junto aos pacientes.
The main results of work on the selection of gourds in the Volgograd Trans-Volga region
Authors: Varivoda E. A. , Koleboshina T. G. , Verbickaya L. N. 
Published: August 2020

Relevance. One of the main methods for solving the problem of providing the population of the Russian Federation with vegetable and melon products is the development of selection and seed production. The creation of new competitive varieties and hybrids will enable the vegetable industry to transfer to a qualitatively new level of development.Material and methods.The object of research is new varieties and hybrids of watermelon, melon and pumpkin, created at the Bykov experimental station in the rainfed conditions of the Volgograd TransVolga region. Methods of creation are intervarietal and interlinear hybridization. Results and conclusions.As a result of breeding work at the station, a number of varieties and heterosis hybrids of melons and gourds were created, which significantly expanded the assortment of the melon breeding industry. Over the past 5 years, 4 varieties of watermelon, 2 heterotic hybrids of watermelon, 3 varieties of melon and 1 grade of pumpkin have been included in the State Register of Breeding Achievements. The assortment of new varieties varies in terms of ripening, dry matter content, shape and color of the fruit background, as well as in color and pulp consistency. The length of the growing season of the created varieties and hybrids of watermelon ranges from 63 days in early ripening (Duet F1, Temp F1, Meteor) to 85 in the mid-ripening variety Malachite. The highest solids content of the new variety of watermelon Medunok is up to 14%. Among melon varieties, the shortest growing season is characterized by the Comet variety up to 70 days. All varieties have a high solids content of 14.0-19.0% and a thick flesh. Promising pumpkin varieties are distinguished by a bright coloration of the pulp, a high carotene content and a long storage period. Thus, the introduction of new varieties of gourds in commodity and home garden melon farming will allow the conveyor growing of products, increase the product mix and the period of consumption of fresh produce.
Plant of Lamiaceae family for cultivation at the vertical hydroponic installation
Authors: Balashova I. T. , Bespalko L. V. , Molchanova A. V. , Pinchuk E. V. , Maschenko N. E. 
Published: August 2020

Relevance. Vertical farming – is a new and advanced direction in greenhouse vegetable cultivation. Expansion biodiversity of plants for vertical farming occur with help of green leafy vegetables. Plants of Lamiaceae family are well known as aromatic and medicinal plants with high content of substances with antioxidant activity. It allows use these plants as a base for the functional nutrition. Leafy parts the plants of Lamiaceae family may be used as aromatic and healthy additions to traditional foods, such as salads, soups and sauces. Goal of the study: analysis the biochemical composition of leafy parts plants of Lamiaceaefamily, cultivated at the multi circle hydroponic construction. Materials and methods. 1) Plants: Monarda fistulosa L. (the breeding sample №5 U.P.), Monarda citriodora Cerv. ex Lag. (Simka variety), Melissa officinalisL. (Zhemchuzhina variety). 2) secondary metabolites: flavonoid glycoside linarozid and steroid glycoside moldstim. Methods. 1) cultivation of plants Lamiaceae family at the 5 circles hydroponic construction; 2) analytic methods: determination of dry matter content, determination of ascorbic acid content, determination sum of chlorophylls and carotenoids, determination sum of antioxidants; 3) statistical methods. Results. First experiment the cultivation of plants Lamiaceae family at the multi circle hydroponic construction was successful. Location of plants at different circles of hydroponic installation didn’t influence the content of dry matter, ascorbic acid and sum of chlorophylls in leafy parts of plants Monarda fistulosaL. The content of dry matter and sum of antioxidants in leafy parts of Monarda fistulosaL. plants of the first cutting is significantly higher than of other cuttings. So, we can recommend the leaves of Monarda fistulosa L. plants of the first cutting for the healthy additions in the scheme of the functional nutrition. Seed treatment with water solutions of secondary metabolites changed significantly the weight of leaves: it was increased in Monarda citriodoraCerv. ex Lag. and in Melissa officinalisL.
EFFECT OF KARAMUNTING LEAF EXTRACT (Melastoma malabathricum L.) ON GLUCOSYLTRANSFERASE ENZYME OF Streptococcus mutans
Authors: Fajar Ferdy Juliannor , Tri Putri Deby Kania , Sukmana Bayu Indra 
Published: August 2020

ABSTRACTBackground: Karamunting leaf extract has secondary metabolite compounds such as tannin, flavonoid, and phenol that have antibacteria potential to be used as an alternative to mouthwash in addition to Chlorhexidine 0.12% to lower the incidence of tooth caries. Caries is caused by several important virulence factors, including Streptococcus mutans Glucosyltransferase (GTF) enzyme. Karamunting leaf extract can inhibit the work of GTF enzyme by precipitating, denaturing protein and damaging cell walls. Inhibition of Streptococcus bacteria enzyme activity will decrease plaque formation, thus decreasing the potential of dental caries. Objective: The purpose of this study was to determine the effect of Karamunting leaf extract and 0,12% Chlorhexidine on Glucosyltransferase enzyme activity of Streptococcus mutans. Methods: This study used true experimental design with post test only with control group design using 7 groups, including Karamunting leaf extract group with 5%, 10%, 15%, 20%, and 25% concentrations to determine the activity of S. mutans GTF enzyme. Results: The results showed that Karamunting leaf extract with 20% concentration was able to decrease the activity of Glucosyltransferase enzyme in Streptococcus mutans. Conclusion: Karamunting leaf extract affects Streptococcus mutans Glucosyltransferase enzyme activity. Keywords: Chlorhexidine 0,12%, Glucosiltransferase, Melastoma malabathricum L., Streptococcus mutans.
GINGIVECTOMY AS A CROWN LENGTHENING PROCEDURE FOR ALTERED PASSIVE ERUPTION TREATMENT
Authors: Bhakti Wildhan Septianda , Krismariono Agung 
Published: August 2020

ABSTRACTBackground: Altered passive eruption is a condition that can make clinical crown of teeth seems shorten. The excessive gum or dentogingival junction level that overlap to enamel become causal factor for altered passive eruption. Crown lengthening is one of treatment that can treat altered passive eruption. One of crown lengthening procedure is gingivectomy. Purpose: To correct excessive gingiva and achieve ideal teeth appearance by using gingivectomy as crown lengthening procedure. Case: A 21‑years‑old, systemically healthy, non‑smoking female, referred from orthodontist to treat patient’s overlap gingiva. From the patient’s point of view, her upper front teeth were unpleasant to see. There were no abnormalities in extraoral. Intraoral, there were upper front clinical crown of teeth that seem shorter. Case management: The treatment started from administration of anesthetic agent, application of pocket marker forceps, gingival cutting and trimming process, then periodontal pack application. Treatment results were quite good. The appearance of upper front teeth became ideal in width and length ratio. Conclusion: Gingivectomy is one of crown lengthening method that can solve excessive gingiva in altered passive eruption.Keywords: Altered passive eruption; Crown lengthening; Dentogingival junction; Gingivectomy
Association between rural-to-urban migration and the cognitive aging trajectories of older Chinese adults: results from a prospective cohort analysis
Authors: Xie Jinzhao , Liao Jing , Zhang Jing , Gu Jing 
Published: August 2020

Abstract
Background: Increasingly, older Chinese adults from rural areas are moving to urban areas to live with their children who have already migrated to these areas. However, few studies have examined this pattern of migration and its effects on cognitive function. We aimed to investigate the association between domestic rural-to-urban migration and the trajectories of cognitive function in older Chinese adults, as well as the factors contributing to these association.Methods: Data for this study were drawn from three waves of the China Health and Retirement Longitudinal Study. Migrants were defined as participants who had rural hukou status (under China’s household registration system) but resided in an urban area. Cognitive functions were measured using an adapted Chinese version of the Mini-Mental State Examination. We used multilevel linear regression models to examine the association between internal migration and cognitive function trajectories.Results: The study included 3,876 Chinese adults aged ≥60 years at baseline. Compared with their rural non-migrant counterparts, migrants (n = 850) had higher levels of education and reported more interactions with family. Additionally, female migrants were more likely to participate in leisure activities. All cognitive function scores declined over time, but no significant differences were observed in rates of cognitive decline between migrants and non-migrants, regardless of sex. Female migrants exhibited significantly better performance in terms of total cognition (β = 0.77, P < .001) and mental status (β=0.68, P < .001) than female non-migrants, whereas no inter-group difference was observed regarding memory (β= 0.09, P > .05). Among the male subjects, no significant differences in cognitive function levels were observed between migrants and non-migrants. A series of adjusted models revealed that psychosocial factors such as residing with children, caring for grandchildren, depression and participation in leisure activities partly explained the association between migration and cognition in women.Conclusions: Rural-to-urban migration was positively associated with cognitive functions only in women. However, this pattern did not affect the rate of cognitive decline in either sex. Our findings provide directions for tailored interventions improving cognitive functions of older adults and rural non-migrating older adults, especially female non-migrants.
Clinical characteristics of adult T-cell leukemia/lymphoma infiltration in the gastrointestinal tract
Authors: Miike Tadashi , Kawakami Hiroshi , Kameda Takuro , Yamamoto Shojiro , Tahara Yoshihiro , Hidaka Tomonori , Kubuki Yoko , Yorita Kenji , Akiyama Yutaka , Arimura Yasuji , Kubota Yoshimasa , Kataoka Hiroaki , Shimoda Kazuya 
Published: August 2020

Abstract
Background: Adult T-cell leukemia/lymphoma (ATLL) is a peripheral T-cell malignancy caused by human T-cell leukemia virus type 1. The clinical course of ATLL is very heterogeneous, and many organs, including the gastrointestinal (GI) tract, can be involved. However, there are few detailed reports on ATLL infiltration in the GI tract. We investigated the clinical characteristics of ATLL infiltration in the GI tract.Methods: This retrospective observational single-center study included 40 consecutive ATLL patients who underwent GI endoscopy. The patients’ demographic and clinical characteristics and endoscopic findings were analyzed retrospectively. Patients with ATLL who were diagnosed by histological examination were divided into two groups based on GI tract infiltration.Results: Multivariate analysis revealed that the absence of skin lesions was significantly associated with GI infiltration (P < 0.05). Furthermore, the infiltration group tended to have similar macroscopic lesions in the upper and lower GI tracts, such as diffuse type, tumor-forming type, and giant-fold type.Conclusions: GI endoscopy may be considered for ATLL patients without skin lesions.
A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
Authors: Warner Ben , Harrison Phillip , Farman Muhammad , Devlin John , Reffitt David , El-Sherif Yasser , Khorsandi Shirin E , Prachalias Andreas , Cerisuelo Miriam Cortes , Menon Krish , Jassem Wayel , Sriniva Parthi , Vilca-Melendez Hector , Heneghan Michael , Heaton Nigel , Joshi Deepak 
Published: August 2020

Abstract
Background: We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum. Methods: 62 patients underwent ERCP and Kaffes stent insertion for post-transplant anastomotic strictures following confirmation of a stricture on MRCP. These patients were retrospectively analysed for immediate and long-term stricture resolution, improvement in symptoms and liver function tests (LFTs), stricture recurrence and complication rates. Results: Of the 56 patients who had their stent removed at the time of analysis, 54 (96%) had immediate stricture resolution and 42 continued to have long-term resolution (mean follow-up period was 548 days). Of the 16 patients with symptoms of biliary obstruction, 13 had resolution of their symptoms. Overall, there was a significant improvement in LFTs after stent removal compared to before stent insertion. Complication rates were 15% with only one patient requiring biliary reconstruction. Conclusions: The Kaffes stent is effective and safe at resolving post liver transplant biliary anastomotic strictures.
Should we remain hopeful? The key 8 weeks: Spatiotemporal epidemic characteristics of COVID-19 in Sichuan Province and its comparative analysis with other provinces in China and global epidemic trends
Authors: Xu Xinyin , Zeng Jing , Liu Runyou , Liu Yang , Zhou Xiaobo , Zhou Lijun , Dong Ting , Cha Yuxin , Wang Zhuo , Deng Ying , Zhang Yu , Feng Liao , Pu Chen , Wu Xianping , Zhong Bo 
Published: August 2020

Abstract
Background: The COVID-19 spread worldwide quickly. Exploring the epidemiological characteristics could provide a basis for responding to imported cases abroad and to formulate prevention and control strategies in areas where COVID-19 is still spreading rapidly.Methods: The number of confirmed cases, daily growth, incidence and length of time from the first reported case to the end of the local cases (i.e., non-overseas imported cases) were compared by spatial (geographical) and temporal classification and visualization of the development and changes of the epidemic situation by layers through maps.Results: In the first wave, a total of 539 cases were reported in Sichuan, with an incidence rate of 0.6462/100,000. The closer to Hubei the population centres were, the more pronounced the epidemic was. The peak in Sichuan Province occurred in the second week. Eight weeks after the Wuhan lockdown, the health crisis had eased. The longest epidemic length at the city level in China (except Wuhan, Taiwan, and Hong Kong) was 53 days, with a median of 23 days. Spatial autocorrelation analysis of China showed positive spatial correlation (Moran's Index >0, p<0.05). Most countries outside China began to experience a rapid rise in infection rates 4 weeks after their first case. Some European countries experienced that rise earlier than the USA. The pandemic in Germany, Spain, Italy, and China took 28, 29, 34, and 18 days, respectively, to reach the peak of daily infections, after their daily increase of up to 20 cases. During this time, countries in the African region and Southeast Asian region were at an early stage of infections, those in the Eastern Mediterranean region and region of the Americas were in a rapid growth phase.Conclusions: After the closure of the outbreak city, appropriate isolation and control measures in the next 8 weeks were key to control the outbreak, which reduced the peak value and length of the outbreak. Some countries with improved epidemic situations need to develop a continuous "local strategy at entry checkpoints" to to fend off imported COVID-19.
Beyond clinical food prescriptions and mobile markets: parent views on the role of a healthcare institution in increasing healthy eating in food insecure families
Authors: DeWit Emily L. , Meissen-Sebelius Emily M. , Shook Robin P. , Pina Kimberly Ann , De Miranda Evelyn Donis , Summar Michelle J. , Hurley Emily A. 
Published: August 2020

Abstract
Background: Children in food-insecure families face increased barriers to meeting recommendations for fruit and vegetable consumption. Hospitals and pediatric healthcare institutions have attempted to alleviate food-insecurity through various internal programs like food prescriptions, yet little evidence for these programs exist. Consistent with a patient-centered perspective, we sought to develop a comprehensive understanding of barriers to fruit and vegetable consumption and a parent-driven agenda for healthcare system action. Methods: We conducted six qualitative focus group discussions (four in English, two in Spanish) with 29 parents and caregivers of patients who had screened positive for food-insecurity during visits to a large pediatric healthcare system in a midwestern U.S. city. Our iterative analysis process consisted of audio-recording, transcribing and coding discussions, aiming to produce a) a conceptual framework of barriers to fruit and vegetable consumption and b) a synthesis of participant programmatic suggestions for their healthcare system.Results: Participants were 90% female, 38% Black/African American and 41% Hispanic/Latino. Barriers to fruit and vegetable consumption in their families fell into three intersecting themes: affordability, accessibility and desirability. Participant-generated intervention recommendations were multilevel, suggesting healthcare systems focus not only on clinic and community-based action, but also advocacy for broader policies that alleviate barriers to acquiring healthy foods. Conclusion: Parents envision an expanded role for healthcare systems in ensuring their children benefit from a healthy diet. Findings offer critical insight on why clinic-driven programs aimed to address healthy eating may have failed and healthcare organizations may more effectively intervene by adopting a multilevel strategy.
LINC02418 promotes colon cancer progression by suppressing apoptosis via interaction with miR-34b-5p/BCL2 axis
Authors: Tian Jun , Cui Peng , Li Yifei , Yao Xuequan , Wu Xiaoyu , Wang Zhirong , Li Chunsheng 
Published: August 2020

Abstract
Background LncRNAs act as functional regulators in tumor progression through interacting with various signaling pathways in multiple types of cancer. However, the effect of LINC02418 on colorectal cancer (CRC) progression and the underling mechanisms remain unclear.Methods LncRNA expression profile in CRC tissues was investigated by the TCGA database. The expressional level of LINC02418 in CRC patients was determined by quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Kaplan-Meier analyses was used to investigate the correlation between LINC02418 and overall survival (OS) of CRC patients. Cell proliferative, migratory and invasive abilities were detected by CCK-8 assays, colony formation assays and trans-well assays in HCT116 and LoVo cells which were stably transduced with sh-LINC02418 or sh-NC. The binding between LINC02418 and miR-34b-5p, and the interaction between miR-34b-5p and BCL2 were determined by dual-luciferase assays. Western blot experiments were conducted to further explore the effect of miR-34b-5p on BCL2 signaling pathway. Rescue experiments were performed to uncover the role of LINC02418 /miR-34b-5p/ BCL2 axis in CRC progression.Results LINC02418 was upregulated in human colon cancer samples when compared with adjacent tissue, and its high expressional level correlated with poor prognosis of CRC patients. LINC02418 promoted cancer progression by enhancing tumor growth, cell mobility and invasiveness of colon cancer cells. Additionally, LINC02418 could physically bind to miR-34b-5p and subsequently affect BCL2 signaling pathway. Down-regulation of LINC02418 reduced cell proliferation, while transfection of miR-34b-5p inhibitor or BCL2 into LINC02418-silenced CRC cells significantly promoted CRC cells growth.Conclusions LINC02418 was upregulated in human CRC samples and could be used as the indicator for prediction of prognosis. LINC02418 acted as a tumor driver by negatively regulating cell apoptosis through LINC02418 /miR-34b-5p/ BCL2 axis in CRC.