bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribución y conservación de Portulaca (Portulacaceae) en Cuba
Authors: García-Beltrán José Angel García-Beltrán , Barrios Valdés Duniel , Toledo González Sandy , Testé Lozano Ernesto 
Published: August 2020

Antecedentes: En Cuba, los estudios sobre Portulaca carecen de un consenso de los taxones presentes. Las especies se encuentran pobremente representadas en colecciones de herbario y para ellas se infieren distribuciones geográficas más amplias. Esta situación dificulta la evaluación de su riesgo de extinción y, por tanto, la implementación de acciones de conservación.
Preguntas: ¿Cómo se distribuyen las Portulaca nativas y naturalizadas en Cuba? ¿Cuál es el estado de conservación de las especies nativas?
Sitio y años de estudio: Cuba, 1902-2020.
Métodos: Se georreferenciaron los registros de presencia de las especies y de cada una se determinó la distribución geográfica, ecológica y fitogeográfica. El estado de conservación de las especies nativas se evaluó según las categorías y criterios de IUCN.
Resultados: Portulaca en Cuba incluye 11 especies nativas (una endémica) y una naturalizada, distribuidas en todo el país, mayormente en complejos de vegetación de costa y matorrales xeromorfos. Tres especies se encuentran En Peligro Crítico, cinco En Peligro, una Casi Amenazada y dos en Preocupación Menor. Las principales amenazas son la ganadería y los incendios. En la mayoría de las especies, menos de la mitad del área de ocupación se encuentra en áreas protegidas.
Conclusiones: Se actualizó la distribución Portulaca en Cuba y se presenta la primera evaluación completa del estado de conservación del género en el país. Entre las especies no pueden identificarse patrones de disyunción o vicarianza, geográfica o ecológica. La mayoría de las especies están amenazadas de extinción, aunque el género está ampliamente representado en áreas protegidas.
Analisis Tingkat Kepuasan Pemustaka Terhadap Layanan Electronic Theses and Dissertations (ETD) Perpustakaan UGM dengan Menggunakan Metode LibQUAL +TM
Authors: Sarwono Sarwono , Isbandini Isbandini , Rahayu Dwi 
Published: August 2020

Penelitian ini bertujuan untuk mengetahui tingkat kepuasan pemustaka di layanan Electronic Theses and Dissertations (ETD) Perpustakaan UGM dikaji dari dimensi Affect of Service (Kinerja Petugas dalam Pelayanan), Information Control (Kualitas Informasi dan Akses Informasi) dan Library as Place (Sarana Prasarana) menggunakan metode LibQUAL+TM
Metode LibQUAL +TM mencakup perhitungan antara nilai yang diberikan oleh pemustaka untuk setiap pertanyaan yang terkait dengan tiga kategori yaitu persepsi, harapan minimum dan harapan ideal. Kepuasan pemustaka diukur dengan menggunakan analisis kesenjangan antara persepsi, harapan minimum, dan harapan ideal yang dalam hal ini adalah Adequacy Gap (AG) dan Superiority Gap (SG).Penelitian ini termasuk dalam penelitian kuantitatif yaitu melalui survei dengan menggunakan kuesioner. Populasi dari penelitian adalah pemustaka layanan ETD Perpustakaan UGM, sedangkan sampel diambil dengan metode strata sampel (stratified sampling). Sampel yang diteliti berjumlah 98 orang.
Dalam penelitian ini dipergunakan alat bantu SPSS for windows versi 20 dengan menggunakan Teknik Mean Difference. Dalam mean difference tersebut ada T-test yang digunakan untuk menguji 4 (empat) variabel dalam kualitas layanan perpustakaan dari rerata persepsinya, rerata harapan minimum, dan rerata harapan ideal
Hasil penelitian menunjukkan bahwa persepsi (P) pemustaka mendapatkan skor 91,7805; harapan minimum (HM) pemustaka mendapatkan skor 86,8215; harapan ideal (HI) pemustaka mendapatkan skor 99,0665; adequacy gap (AG) pemustaka mendapatkan skor 4,959; dan superiority gap (SG) pemustaka mendapatkan skor -7,2855. Data tersebut menunjukkan bahwa skor “persepsi” sudah memenuhi “harapan minimum” namun belum memenuhi “harapan ideal”. Sedangkan skor AG bernilai positif berarti menunjukkan bahwa layanan yang diberikan telah melebihi atau memenuhi harapan minimum pemustaka.
Setelah dikaji menggunakan metode LibQUAL+TM , kesimpulan dari penelitian ini menunjukkan bahwa tingkat kepuasan pemustaka layanan ETD Perpustakaan UGM pada dimensi Affect of Service (Kinerja Petugas dalam Pelayanan) adalah “cukup puas” dan “dalam batas toleransi”; tingkat kepuasan pemustaka layanan ETD Perpustakaan UGM pada dimensi Information Control (Kualitas Informasi dan Akses Informasi) adalah “cukup puas” dan “dalam batas toleransi”; tingkat kepuasan pemustaka layanan ETD Perpustakaan UGM pada dimensi Library as Place (sarana dan prasarana perpustakaan) adalah “cukup puas” dan “dalam batas toleransi”
Who Should Drive Efficient Digital Oilfields Transformation Strategy?
Authors: Udofia Emmanuel , Egwu Saviour , Akpabio Julius , Udofia Edwin , Buduka Stanley 
Published: August 2020

Abstract
Efficient Project Management in Digital Oilfields (DOF) space usually focus in addressing the asset business challenges through clearly defined business objectives for the project implementation. One of the key reason why such digital oilfields project implementation fails is because most operating asset use the ‘conventional project management approach’ in dealing with digital oilfields implementation. The ‘Conventional Project Management’ approach rest the entire responsibility of managing the project on the Project Manager who is normally NOT a member of the business or asset. This Project Manager usually abandons this role of managing the implementation after ‘Go Live’ or on ‘completion’ of the project. The objective of this presentation is to identify the reasons why the ‘conventional project management framework’ fails and proffer a field-tested project management approach that ensures seamless embedment of the Digital Oilfields Transformation solutions.
A field-tested approach is demonstrated through research work in a field where a Business Opportunity Manager (BOM) who is a member of the business (not from the project team) who actually anchored the implementation of digital oilfields solutions in an asset in Gulf of Guinea. The Business Opportunity Manager actually interfaces between the business and the project team right from inception of the project through into the handover of the project to the business thereby ensuring seamless embedment and sustainability of the realised solutions for continuous business improvement.
Digital Oilfields (DOF) Transformation is a continuous business improvement initiative in project management. The results show significant business benefits from this option of using the Business Opportunity Manager from the business in delivering the solutions rather than the conventional project manager that takes overall management of the project and leaves on ‘completion’ of the project implementation. The gains or value proposition from the DOF implementation are sustained and continuously improved with solid embedment process. This result will serve as reference tool and assist Digital Transformation experts build a sustainable framework in similar project implementation and management, globally.
Application of a Classroom-Based Positive Psychology Education Course for Chinese Medical Students to Increase Their Psychological Well-Being: A Pilot Study
Authors: Zhang Xiao-Qin , Zhang Bao-Shuai , Wang Meng-Die 
Published: August 2020

Abstract
Background Anxiety and depression have been increasing among Chinese medical students. The psychological well-being of Chinese medical students has become a critical focus of attention for the medical education community. Increasing evidence shows that positive psychology interventions can be effective in the enhancement of psychological well-being, and may help to prevent depressive symptoms in university students. In the present study, we aimed to explore the potential effect of positive psychology education on improving the mental health of Chinese medical students. Methods An 8-week classroom-based positive psychology intervention workshop, which was established as an elective course embedded in the regular school curriculum, was conducted at the School of Medicine, South China University of Technology (SCUT), China. Undergraduate medical students of the institute in year-2 or year-3 of academic study participated in this training course voluntarily. The participants’ self-reported data on the hope scale, life satisfaction scale, subjective happiness scale, and depression and anxiety scale were collected and analyzed at pre-course (n=61) and post-course (n=49) times. The investigation was also validated with an independent cohort of students who enrolled in the course in the year following the preliminary study. Results The analyses showed that the psychological well-being of the participants were improved after the intervention. Their mean scores on the hope scale, life satisfaction scale and subjective happiness scale were significantly improved (P<0.05), while their symptom levels of depression and anxiety were significantly reduced (P<0.01). A similar trend was observed in the validation cohort. Conclusions These preliminary findings suggest that positive psychology education holds promise for improving psychological well-being among Chinese medical students. Further investigations with larger and well-controlled sample cohorts may yield more convincing and reliable results.
Comparative Efficacy of Glucocorticoid Receptor Agonists on Th2 Cell Function and Attenuation by Progesterone
Authors: Luchak Alexander , Solomon Lauren A , Kanagalingam Tharsan , Vijeyakumaran Meerah , Rowe Brian H , Cameron Lisa 
Published: August 2020

Abstract
Background: Corticosteroids (CS)s suppress cytokine production and induce apoptosis of inflammatory cells. Prednisone and dexamethasone are oral CSs prescribed for treating asthma exacerbations. While prednisone is more commonly prescribed, dexamethasone is long acting and a more potent glucocorticoid receptor (GR) agonist. It can be administered as a one or two dose regime, unlike the five to seven days required for prednisone, a feature that increases compliance. We compared the relative ability of these two oral CSs to suppress type 2 inflammation. Since progesterone has affinity for the GR and women are more likely to relapse following an asthma exacerbation, we assessed its influence on CS action. Results: Dexamethasone suppressed the level of IL-5 and IL-13 mRNA within Th2 cells with ~10-fold higher potency than prednisolone (the active form of prednisone). Dexamethasone induced a higher proportion of apoptotic and dying cells than prednisolone, at all concentrations examined. Addition of progesterone reduced the capacity of both CS to drive cell death, though dexamethasone maintained significantly more killing activity. Progesterone blunted dexamethasone-induction of FKBP5 mRNA, indicating that the mechanism of action was by interference of the GC:GR complex. Conclusions: Dexamethasone is both more potent and effective than prednisolone in suppressing type 2 cytokine levels and mediating apoptosis. Progesterone attenuated these anti-inflammatory effects, indicating its potential influence on CS responses in vivo. Collectively, our data suggest that when oral CS is required, dexamethasone may be better able to control type 2 inflammation, eliminate Th2 cells and ultimately lead to improved long-term outcomes. Further research in asthmatics is needed.
Motivations, experiences and aspirations of Trainee Nursing Associates in England. A qualitative study
Authors: King Rachel Louise , Wood Emily , Robertson Steve , Ryan Tony , Tod Angela 
Published: August 2020

Abstract
Background: The nursing associate role was developed in England in response to the ‘Shape of Caring’ review. It has been implemented to fulfil two aims; to bridge the gap between registered nurses and healthcare assistants, and to provide an alternative route into registered nursing in light of workforce shortages. Other high income countries deploy second level nurses within their healthcare systems, however the UK has a turbulent history with such roles. The previous state enrolled nurse was phased out in the 1990s, and more recently the assistant practitioner (AP) role has faced wide variation in titles, scope and pay. Little is known about those who have embarked on the new nursing associate training course and their experiences of the role. Methods: An exploratory qualitative study was undertaken using focus groups of trainee nursing associates to generate in-depth discussion about their motivations, experiences of training, and career aspirations.Three focus groups (n=15) took place in December 2018 using a purposive sample of trainee nursing associates registered at a University in the North of England. Two researchers facilitated each group discussion at a time and place convenient for participants. The discussions were audio recorded, transcribed and data was analysed thematically.Results: This study found that trainee nursing associates are motivated by affordable, local, career development. During training they face challenges relating to clinical support, academic workload and uncertainty about future career opportunities. They experience role ambiguity both individually and across the wider organisation. Trainee nursing associates rely on broad support networks to build their occupational identity.Conclusions: The barriers and facilitators of trainee nursing associate personal development have implications for policy and practice relating to recruitment and retention. The results increase our understanding of this emerging role, and have informed the development of a larger longitudinal cohort study. Further research is required to evaluate the impact of this new role.
Improved ascertainment of modes of HIV transmission in Ukraine indicates importance of drug injecting and homosexual risk
Authors: Dumchev Kostyantyn , Kornilova Marina , Kulchynska Roksolana , Azarskova Marianna , Vitek Charles 
Published: August 2020

Abstract
Background: It is important to understand how HIV infection is transmitted in the population in order to guide prevention activities and properly allocate limited resources. In Ukraine and other countries where injecting drug use and homosexuality are stigmatized, the information about mode of transmission in case registration systems is often biased.Methods: We conducted a cross-sectional survey in a random sample of patients registered at HIV clinics in seven regions of Ukraine in 2013-2015. The survey assessed behavioral risk factors and serological markers of viral hepatitis B and C. We analyzed the discrepancies between the registered mode of transmission and the survey data, and evaluated trends over three years.Results: Of 2,285 participants, 1,032 (45.2%) were females. The proportion of new HIV cases likely caused by injecting drug use based on the survey data was 59.7% compared to 33.2% in official reporting, and proportion of cases likely acquired through homosexual transmission was 3.8% compared to 2.8%. We found a significant decrease from 63.2% to 57.5% in the proportion of injecting drug use-related cases and a steep increase from 2.5 to 5.2% in homosexual transmission over three years. Conclusions: The study confirmed the significant degree of misclassification of HIV mode of transmission among registered cases. The role of injecting drug use in HIV transmission is gradually decreasing, but remains high. The proportion of cases related to homosexual transmission is relatively modest, but is rapidly increasing, especially in younger men. Improvements in ascertaining the risk factor information are essential to monitor the epidemic and to guide programmatic response.
Unraveling the molecular heterogeneity in type 2 diabetes: A potential subtype discovery followed by metabolic modeling
Authors: Khoshnejat Maryam , Kavousi Kaveh , Banaei-Moghaddam Ali Mohammad , Moosavi-Movahedi Ali Akbar 
Published: August 2020

Abstract
BackgroundType 2 diabetes mellitus (T2DM) is a complex multifactorial disease with a high prevalence worldwide. Insulin resistance and impaired insulin secretion are the two major abnormalities in the pathogenesis of T2DM. Skeletal muscle is responsible for over 75% of the glucose uptake and plays a critical role in T2DM. Here, we sought to provide a better understanding of the abnormalities in this tissue. MethodsThe muscle gene expression patterns were explored in healthy and newly diagnosed T2DM individuals using supervised and unsupervised classification approaches. Moreover, the potential of subtyping T2DM patients was evaluated based on the gene expression patterns.ResultsA machine-learning technique was applied to identify a set of genes whose expression patterns could discriminate diabetic subjects from healthy ones. A gene set comprising of 26 genes was found that was able to distinguish healthy from diabetic individuals with 94% accuracy. In addition, three distinct clusters of diabetic patients with different dysregulated genes and metabolic pathways were identified. Conclusions This study indicates that T2DM is triggered by different cellular/molecular mechanisms, and it can be categorized into different subtypes. Subtyping of T2DM patients in combination with their real clinical profiles will provide a better understanding of the abnormalities in each group and more effective therapeutic approaches in the future.
Soft tissue sarcoma in adolescent and young adult patients: A retrospective study using a nationwide bone and soft tissue tumor registry in Japan.
Authors: Fukushima Takashi , Ogura Koichi , Akiyama Toru , Takeshita Katsushi , Kawai Akira 
Published: August 2020

Abstract
BackgroundCompared to young children or older adults, the prognoses of adolescent and young adult (AYA) patients with cancer, i.e., those aged from 15 to 39 years, have not improved. In this study, we focused on soft tissue sarcoma (STS) in AYA patients and aimed to determine whether there is a correlation between the AYA age group and overall poor cancer survival in STS. We further aimed to determine which histologic subtypes are more common in AYA patients and investigate the cause of poor outcomes in this group.MethodsThe medical records of 5853 Japanese patients diagnosed with STS between 2006 and 2013 were accessed from the Bone and Soft Tissue Tumor registry (BSTT). We analyzed and compared the epidemiological features of AYA patients with those of other age groups. The cancer survival rates were calculated using the Kaplan-Meier method. Cox proportional hazards models were used to analyze the prognostic factors for cancer survival. The primary endpoint for prognosis was the occurrence of tumor-related death.ResultsOn multivariate analysis, age was not a prognostic factor for poor cancer survival among these patients. Compared to the same categories in other age groups, the proportions of myxoid/round cell liposarcomas, synovial sarcomas, malignant peripheral nerve sheath tumors (MPNST), primitive neuroectodermal tumor, and rhabdomyosarcoma in AYA patients were the highest, but none of the categories were significantly more prevalent in AYA patients. The cancer survival rates of AYA patients with MPNST were poorer than those of the other age groups; however, AYA age was not a prognostic factor on multivariate analysis in MPNST patients.ConclusionsOur study is the first to investigate STS in AYA patients using the nationwide BSTT registry. Our findings demonstrate that AYA age is not a prognostic factor for poor cancer survival among those with STS in Japan.
Classifying maternal deaths in Suriname using WHO ICD-MM: different interpretation by physicians, national and international maternal death review committees
Authors: Kodan Lachmi , Verschueren Kim J.C. , McCaw-Binns Affette M. , Fat Ray Tjon Kon , Browne Joyce L. , Rijken Marcus J. , Bloemenkamp Kitty W.M. 
Published: August 2020

Abstract
Background Insight into the underlying causes of pregnancy-related deaths is essential to develop policies to avert preventable deaths. The WHO International Classification of Diseases-Maternal Mortality (ICD-MM) guidelines provide a framework to standardize maternal death classifications and enable comparison in and among countries over time. However, despite the implementation of these guidelines, differences in classification remain. We evaluated consensus on maternal death classification using the ICD-MM guidelines. Methods The classification of pregnancy-related deaths in Suriname during 2010-2014 was compared in the country (between the attending physician and the national maternal death review (MDR) committee), and among the MDR committees from Suriname, Jamaica and the Netherlands. All reviewers applied the ICD-MM guidelines. The inter-rater reliability (Fleiss kappa [κ]) was used to measure agreement.Results Out of the 89 cases certified by attending physicians, 47% (n=42) were classified differently by the Surinamese MDR committee. The three MDR committees agreed that 18% (n=16/89) of these cases were no maternal deaths, and, therefore, excluded from further analyses. However, opinions differed whether 15% (n=11) of the remaining 73 cases were maternal deaths. The MDR committees achieved moderate agreement classifying the deaths into type (direct, indirect and unspecified) (κ=0.53) and underlying cause group (κ=0.52). The Netherlands MDR committee classified more maternal deaths as unspecified (19%), than the Jamaican (7%) and Surinamese (4%) committees did. The mutual agreement between the Surinamese and Jamaican MDR committees (κ=0.69 vs κ=0.63) was better than between the Surinamese and the Netherlands MDR committees (κ=0.48 vs κ=0.49) for classification into type and underlying cause group, respectively. Agreement on the underlying cause category was excellent for abortive outcomes (κ=0.85) and obstetric hemorrhage (κ=0.74) and fair for unspecified (κ=0.29) and other direct causes (κ=0.32). Conclusions Maternal death classification differs in Suriname and among MDR committees from different countries, despite using the ICD-MM guidelines on similar cases. Specific challenges in applying these guidelines included attribution of underlying cause when comorbidities occurred, the inclusion of deaths from suicides, and maternal deaths that occurred outside the country of residence.