bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perbedaan Nyeri Sebelum dan Sesudah Dilakukan Teknik Relaksasi pada Pasien Sectio Caesarea di Rumah Sakit Grand Medlubuk Pakam
Authors: Wulan Sri , Gurusinga Rahmad 
Published: February 2020

Operasi Caesar adalah proses persalinan yang dilakukan dengan cara melahirkan janin dengan membuat sayatan pada dinding uterus melalui dinding depan perut atau vagina. Nyeri yang dirasakan ibu pasca sectio caesarea berasal dari luka yang terdapat dari perut. Nyeri adalah pengalaman sensori dan emosional yang tidak menyenangkan akibat dari kerusakan jaringan yang aktual atau potensial. Tingkat dan keparahan nyeri pasca operatif terganggu pada fisiologis dan psikologis individu dan toleransi yang ditimbulkan nyeri. Rasa nyeri berbeda pada setiap individu. Melalui pengalaman nyeri, manusia mengembangkan beraneka mekanisme untuk mengatasi nyeri.
Tujuan penelitian ini untuk mengetahui perbedaan nyeri sebelum dan sesudah dilakukan
teknik relaksasi pada pasien section caesarea di Rumah Sakit Grandmed Lubuk Pakam. Jenis penelitian ini adalah pre eksperimen dengan model rancangan one group pretest postest. Data diambil dengan menggunakan lembar observasi yang selanjutnya dianalisa. Sampel pada penelitian ini adalah pasien sectio caesarea di Rumah Sakit Umum Grandmed Lubuk Pakam sebanyak 11 orang. Berdasarkan hasil uji statistik dengan menggunakan uji t-Test menunjukan bahwa p_Value=0.002<0.05 yang artinya ada perbedaan nyeri sebelum dan sesudah dilakukan teknik relaksasi pada pasien section caesarea di Rumah Sakit Grandmed Lubuk Pakam. Disarankan agar dapat menerapkan teknik relaksasi apabila terjadi nyeri sehingga dapat menjadikan pasien mandiri.
ANALISIS MENU UNTUK MENENTUKAN STRATEGI BAURAN PEMASARAN PADA BUNUT CAFÉ DI HOTEL WHITE ROSE LEGIAN KUTA
Authors: Suryawati Dewa Ayu , Osin Rosvita Flaviana 
Published: February 2020

Perkembangan industri pariwisata baik berupa hotel, restoran, dan tempat-tempat rekreasi lainnya turut mengiringi perkembangan pariwisata di Bali. Banyaknya industri pariwisata yang berkembang khususnya restoran, menimbulkan persaingan semakin ketat. Semua pelaku industri restoran menginginkan pertumbuhan dan perkembangan dalam usahanya. Untuk mencapai tujuan tersebut, salah satu yang bisa dilakukan adalah menganalisis menu yang dijual untuk menentukan strategi bauran pemasaran sehingga dapat mencapai keuntungan yang diinginkan secara optimal. Tujuan dari penelitian ini adalah untuk mengetahui dan memaparkan tingkat popularitas dari menu a’la carte untuk lunch dan dinner serta menentukan strategi buaran pemasaran apa yang harus diambil oleh pihak manajemen hotel.Dalam penelitian ini digunakan data kualitatif dan kuantitatif yaitu data-data yang berupa informasi dan angka-angka dari data intern dan ekstern. Data ini dikumpulkan dan diolah dengan teknik analisis menu engineering. Hasil dari penelitian ini menunjukan bahwa dari keseluruhan a’la carte menu yang ditawarkan pada Bunut Café dari 74 makanan , 29,73% atau 22 item tergolong menu Star (popular dan menguntungkan), 25.68% atau 19 item menu tergolong kelas menu Plowhorse (popular tetapi tidak menguntungkan), 28.38% atau 21 item tergolong kelas menu Puzzle (tidak popular tetapi menguntungkan), 16.22% atau 12 item tergolong kelas menu Dog (tidak popular dan tidak menguntungkan).
Kata kunci: Analisis Menu, Strategi, Bauran Pemasaran
Pengaruh Kompetensi Spiritual terhadap Kedisiplinan Siswa di Lingkungan Sekolah
Authors: Al-Azwi Nadhifah Mizana , Rohmah Siti 
Published: February 2020

Education is essentially a conscious effort to develop the personality that is in a person to be better, smarter, creative and innovative. Spiritual competence is character and attitude which is the deepest part of awareness in a person related to which not only recognizes the awareness of fixed values but is also creative in finding new values. Discipline is a process of training the mind and character of children gradually so that they become someone who has self-control and is useful for the community. This study aims to determine whether there is a influence between Spiritual competence and student discipline in the MTs Darul Qudwah Tegal School environment. This type of research is correlation research, which explains whether there is a influence between variable X as an independent or independent variable (Spiritual Competence) and Y as a dependent variable (Discipline). The population in this study were some students of MTs Darul Qudwah Tegal, totaling 63 students. In this study the sampling technique used was purposive sampling technique, namely sampling data. Based on this research, spiritual competence variable (X) is obtained which influences discipline variable (Y) where there is a positive influence meaning higher variable X and higher Y variable.
Aspects du temps dans l’antiquité
Authors: Poirier Jean-Louis 
Published: February 2020

Le temps ne peut être disjoint de l’éternité. « Image mobile de l’éternité immobile » selon Platon, dans le Timée , il permet à la réalité sensible d’être stable et de durer, en lui apportant le pouvoir d’imiter l’éternité par son mouvement cyclique. Avec le christianisme, malgré l’abandon de la figure cyclique, ordonné à une signification historique, le temps conserve ce pouvoir organisateur, dans un monde à l’image de Dieu. Mais c’est la déficience du temps, mise en scène dans les mythes de la religion gnostique, dans le contexte anxiogène d’une création ratée, œuvre d’un dieu incompétent, qui met en évidence, quoique sur un mode négatif, l’articulation essentielle du temps et de l’éternité.
La religion libérale pour les personnes et pour les groupes
Authors: Seymour Michel , Gosselin-Tapp Jérôme 
Published: February 2020

Cet article vise à enrichir l’approche désagrégative proposée par Cécile Laborde dans Liberalism’s Religion [HUP, 2017] à l’aide de certaines intuitions rawlsiennes provenant de notre ouvrage La nation pluraliste [PUM, 2018]. En partant de la notion d’« accommodement raisonnable » telle que comprise dans le contexte légal du Québec et du Canada, nous parvenons à une interprétation des fondements normatifs de la distinction entre droits fondamentaux et accommodements qui repose sur la raison publique. La perspective que nous défendons permet ultimement d’admettre des droits fondamentaux à la fois pour les personnes et pour les groupes.
The Status of Insect Pests Prevailing in Stored Wheat Grain under Traditional Storages of Cheha District of Gurage Zone of South Central Ethiopia
Authors: Wubetu Tsehaynew , Hiruy Berhanu 
Published: February 2020

Aim: To assess the status of the insect pests of stored wheat grains in Cheha destrict of Gurage Zone of Southern Ethiopia.
Study Design: Peasant associations were selected purposefully based on intensity of wheat production, such that those peasant association growing wheat predominantly were selected for the survey, while villages, representative farmers and their storage systems were selected randomly using a nested design.
Place and Duration of Study: Survey was conducted between 1, July to 30, December 2019 with the interval of one month in major wheat growing peasant associations of Cheha district of south central Ethiopia.
Methodology: The assessment on abundance was made from of half kilogram of wheat grain sample taken from 135 randomly selected farmer’s storages of three peasant associations using taxonomic keys of books related to stored product insects.
Results: Eight major species of insect pests consisting of four primary pests and four secondary pests belonging to five families with in two insect orders were documented. Of these pests recorded, Sitophilus oryzae, Sitophilus zeamais, Sitotroga cereallella, Tribolium castaneum and Tribolium confusum, respectively were the most prevalent and frequently occurring as they appeared between 12.74 and 33.78 individuals per 100 g of grain and as they occurred in the range between 77.78 and 92.26% per 100 g of sample wheat grain collected from the survey sites, respectively. These were followed by Cryptolestes ferrugineus, Cryptolestes pusillus and Rhyzopertha dominica which occurred between 7.26 and 10.74 individuals per 100 g of grain and in ranges between 51.85 and 66.67% per 100 g of sample wheat grain collected.
Conclusion: The traditional methods and practices used by farmers were inefficient for sufficient wheat grains protection against insect pests in storages; this implies for the urgent need for designing management strategies for more effective and sustainable methods of control.
Aryldiazenyl Radicals from Arylazo Sulfones: Visible Light‐Driven Diazenylation of Enol Silyl Ethers
Authors: Othman Abdulla Havall , Scaringi Simone , Amin Ahmed A. , Mella Mariella , Protti Stefano , Fagnoni Maurizio 
Published: February 2020

AbstractA versatile protocol for the diazenylation of enol silyl ethers under visible light irradiation is presented herein. The reaction is based on the underused reaction of a nitrogen‐based radical (the diazenyl radical) with an enol silyl ether. Arylazo sulfones were used as photoactivatable precursors of these diazenyl radicals. The resulting azaderivatives are potentially bioactive compounds as well as starting materials for the synthesis of N‐containing heterocycles.magnified image
A Thermomorphic Polyethylene‐Supported Imidazolium Salt for the Fixation of CO2 into Cyclic Carbonates
Authors: Grollier Kevin , Vu Nam Duc , Onida Killian , Akhdar Ayman , Norsic Sébastien , D'Agosto Franck , Boisson Christophe , Duguet Nicolas 
Published: February 2020

AbstractAn imidazolium catalyst supported on thermomorphic polyethylene (PE) was prepared from 1‐methylimidazole and polyethylene iodide (PE−I). The catalyst was characterized by 1H and 13C NMR, SEC and MALDI‐ToF mass spectrometry. Its catalytic activity was evaluated in the ring‐opening of epoxides with carbon dioxide to give cyclic carbonates under solvent‐free conditions. The catalyst proved to be active at low catalyst loading (down to 0.1 mol%) and allows the reaction to occur at low CO2 pressure (1–5 bar) and moderate temperature (100 °C). A range of terminal and internal epoxides was converted to the corresponding cyclic carbonates with high yields and selectivities. The recyclability of the catalyst was studied and no significant loss of activity was observed after 5 runs.magnified image
Achieving 21% External Quantum Efficiency for Nondoped Solution‐Processed Sky‐Blue Thermally Activated Delayed Fluorescence OLEDs by Means of Multi‐(Donor/Acceptor) Emitter with Through‐Space/‐Bond Charge Transfer
Authors: Zheng Xujun , Huang Rongjuan , Zhong Cheng , Xie Guohua , Ning Weimin , Huang Manli , Ni Fan , Dias Fernando B. , Yang Chuluo 
Published: February 2020

AbstractAlthough numerous thermally activated delayed fluorescence (TADF) organic light‐emitting diodes (OLEDs) have been demonstrated, efficient blue or even sky‐blue TADF‐based nondoped solution‐processed devices are still very rare. Herein, through‐space charge transfer (TSCT) and through‐bond charge transfer (TBCT) effects are skillfully incorporated, as well as the multi‐(donor/acceptor) characteristic, into one molecule. The former allows this material to show small singlet–triplet energy splitting (ΔEST) and a high transition dipole moment. The latter, on the one hand, further lights up multichannel reverse intersystem crossing (RISC) to increase triplet exciton utilization via degenerating molecular orbitals. On the other hand, the nature of the molecular twisted structure effectively suppresses intermolecular packing to obtain high photoluminescence quantum yield (PLQY) in neat flims. Consequently, using this design strategy, T‐CNDF‐T‐tCz containing three donor and three acceptor units, successfully realizes a small ΔEST (≈0.03 eV) and a high PLQY (≈0.76) at the same time; hence the nondoped solution‐processed sky‐blue TADF‐OLED displays record‐breaking efficiency among the solution process‐based nondoped sky‐blue OLEDs, with high brightness over 5200 cd m−2 and external quantum efficiency up to 21.0%.
Evidence‐based Medicine Simulation: A Novel and Practice‐relevant Approach to Teaching Real‐time Literature Searching to Emergency Medicine Residents
Authors: Colmers‐Gray Isabelle N. , Ha David J. , Tan Maria C. , Dong Sandy L. 
Published: February 2020

AbstractIntroductionEvidence‐based medicine (EBM) and literature searching skills are competencies within the emergency medicine (EM) residency curriculum. Previously in our residency program, a librarian taught literature searching instruction, including a classroom‐based overview of search engines. Learners reported low engagement and poor retention. To improve engagement, interest, and skill retention, we used a novel approach: simulation to teach real‐time literature searching.MethodsBased on a needs assessment of our EM residents, we created a literature searching workshop using a flipped classroom approach and high‐fidelity simulation. Goals of the session were to be interactive, engaging, and practice‐relevant. With a librarian, we developed a brief list of EM‐relevant databases, including tips for searching and links to sites/apps. Prereadings also covered the hierarchy of evidence and formulating a good clinical (PICO) question. Residents (12 junior residents) participated in a high‐fidelity simulation involving a stable patient whose management required a literature search to inform decisions. Feedback was collected on the simulation experience.ResultsResidents received the list of EM‐relevant databases 7 days prior and were instructed to set up and test the resources on their smartphones. The day of the session, one resident volunteered to lead the simulation; all residents participated in the search on their smart phones. Collectively, it took 4.5 minutes to find a study that adequately addressed the clinical question and to manage the patient accordingly. Feedback on the simulation was positive. Students found it “very real and practical” and “immediately institutable into practice.” It helped residents learn to efficiently and effectively search the literature while managing a stable patient.ConclusionA flipped‐classroom simulation‐based teaching strategy made learning literature searching more interesting, engaging, and applicable to EM practice. Based on popular demand, we will continue to use this teaching method.
Preparation and characterization study on maleic acid cross‐linked poly(vinyl alcohol)/chitin/nanocellulose composites
Authors: Mok Chun Fah , Ching Yern Chee , Abu Osman Noor Azuan , Muhamad Farina , Mohd Junaidi Mohd Usman , Choo Jia H. 
Published: February 2020

AbstractIn the quest on improving composite formulations for environmental sustainability, maleic acid (MA) cross‐linked poly(vinyl alcohol) (PVA)‐α‐chitin composites reinforced by oil palm empty fruit bunch fibers (OPEFB)‐derived nanocellulose crystals (NCC) had been successfully prepared. Based on the Fourier transform infrared (FTIR) spectroscopic analysis, it was proven that molecular interactions of the cross‐linker to the polymeric networks was through conjugated ester linkage. Differential scanning calorimetry (DSC) showed that the influence of MA was minimal toward crystallization in the PVA/chitin/NCC composite. Maximum tensile strength, elongation at break and Young's modulus of the respective PVA/chitin/NCC composites were achieved at different content of MA, dependent on the PVA/chitin mass ratio. Among all compositions, a maximum Young's modulus was achieved at 30 wt% MA loading in PVA/chitin‐30/NCC, amounting to 2,413.81 ± 167.36 MPa. Moreover, the mechanical properties and selected physicochemical properties (swelling, gel content, and contact angle) of the PVA/chitin/NCC composites could be tailored by varying the chitin content (10–30 wt%) and MA content (10–50 wt% based on total mass of composite). In brief, this chemically cross‐linked PVA‐based biocomposites formulated with sustainable resources exhibited tunable physicochemical and mechanical properties.
Climate variability and trends in the reproductive habitat of the critically endangered hooded grebe
Authors: Lancelotti Julio L. , Pessacg Natalia L. , Roesler Ignacio C. , Pascual Miguel A. 
Published: February 2020

AbstractThe population of the critically endangered hooded grebe (Podiceps gallardoi) has decreased drastically during recent decades. The effects of climate change on their reproductive area (Southern Patagonia) have been proposed as one of the potential causes of their critical situation. However, there is much uncertainty about climate variability and climate trends at local scales in Patagonia, and their effects on the hooded grebe habitat.Variability and trends in temperature, precipitation, and wind from 1960 to 2016 in one of the most important reproductive areas of hooded grebe – the Lake Strobel plateau – were analysed. A Landsat satellite image series (1973–2016) was used to evaluate changes in lake area in the region.Generalized linear models were used to analyse the relationship between the variation in lake area and climatic variables, including the Antarctic Oscillation Mode (AAO) index, which is the most important year to year pattern in climate variability at high latitudes of the Southern Hemisphere.High inter‐annual variability and increasing coefficients of variation in precipitation and wind were found, as well as a significant positive trend in temperature. Total lake area, as well as the area specifically used by hooded grebe to reproduce, decreased significantly over time, with high inter‐annual variability. Variation in lake area was significantly correlated with variation in precipitation, and with the AAO index.The loss of reproductive habitat may force the hooded grebe to use sub‐optimal environments, such as lakes with lower food supply, lower macrophyte cover, and less protection from wind – a potential major handicap for this declining species.Information on lake variation in response to climatic variability could be used to guide hooded grebe conservation strategies, directing more resources and special efforts to those reproductive lakes that are more resilient to the effects of climate fluctuations.
A Hands‐On Organ‐Slicing Activity to Teach the Cross‐Sectional Anatomy
Authors: Li Lei , Li Lin , Zuo Yizhi 
Published: February 2020

The presentation of pre‐sliced specimens is a frequently used method in the laboratory teaching of cross‐sectional anatomy. In the present study, a new teaching method based on a hands‐on slicing activity was introduced into the teaching of brain, heart, and liver cross‐sectional anatomy. A randomized, controlled trial was performed. A total of 182 third‐year medical students were randomized into a control group taught with the prosection mode (pre‐sliced organ viewing) and an experimental group taught with the dissection mode (hands‐on organ slicing). These teaching methods were assessed by testing the students' knowledge of cross‐sectional specimens and cross‐sectional radiological images, and analyzing students' feedback. Using a specimen test on three organs (brain, heart, and liver), significant differences were observed in the mean scores of the control and experimental groups: for brain 59.6% (±14.2) vs. 70.1% (±15.5), (P < 0.001, Cohen's d = 0.17); for heart: 57.6% (±12.5) vs. 75.6% (±15.3), (P < 0.001, d = 0.30); and for liver: 60.4% (±14.5) vs. 81.7% (±14.2), (P < 0.001, d = 0.46). In a cross‐sectional radiological image test, better performance was also found in the experimental group (P < 0.001). The mean scores of the control vs. experimental groups were as follows: for brain imaging 63.9% (±15.1) vs. 71.1% (±16.1); for heart imaging 64.7% (±14.5) vs. 75.2% (±15.5); and for liver imaging 61.1% (±15.5) vs. 81.2% (±14.6), respectively. The effect sizes (Cohen's d) were 0.05, 0.23, and 0.52, respectively. Students in the lower tertile benefited the most from the slicing experiences. Students' feedback was generally positive. Hands‐on slicing activity can increase the effectiveness of anatomy teaching and increase students' ability to interpret radiological images.
Synthetic sRNA‐Based Engineering of Escherichia coli for Enhanced Production of Full‐Length Immunoglobulin G
Authors: Zhang Jinhua , Zhao Yanshu , Cao Yingxiu , Yu Zhenpeng , Wang Guoping , Li Yiqun , Ye Xiaoqiong , Li Congfa , Lin Xue , Song Hao 
Published: February 2020

AbstractProduction of monoclonal antibodies (mAbs) receives considerable attention in the pharmaceutical industry. There has been an increasing interest in the expression of mAbs in Escherichia coli for analytical and therapeutic applications in recent years. Here, a modular synthetic biology approach is developed to rationally engineer E. coli by designing three functional modules to facilitate high‐titer production of immunoglobulin G (IgG). First, a bicistronic expression system is constructed and the expression of the key genes in the pyruvate metabolism is tuned by the technologies of synthetic sRNA translational repression and gene overexpression, thus enhancing the cellular material and energy metabolism of E. coli for IgG biosynthesis (module 1). Second, to prevent the IgG biodegradation by proteases, the expression of a number of key proteases is identified and inhibited via synthetic sRNAs (module 2). Third, molecular chaperones are co‐expressed to promote the secretion and folding of IgG (module 3). Synergistic integration of the three modules into the resulting recombinant E. coli results in a yield of the full‐length IgG ≈150 mg L−1 in a 5L fed‐batch bioreactor. The modular synthetic biology approach could be of general use in the production of recombinant mAbs.
Next‐Generation Microbial Workhorses: Comparative Genomic Analysis of Fast‐Growing Vibrio Strains Reveals Their Biotechnological Potential
Authors: Peng Yuan , Han Xiao , Xu Ping , Tao Fei 
Published: February 2020

AbstractVibrio is a recognized fast‐growing bacterial genus, which is considered to be attractive for the development of next‐generation biotechnological workhorses. Here, three Vibrio strains FA1, FA2, and FA3, capable of growing rapidly in cost‐effective media, are isolated and systematically evaluated. Genome sequencing and comparative genomic analyses are performed to reveal the underlying genetic differences between the strains and estimate their biotechnological potential. Studies of their phylogenetic tree, colinear visualization, and orthology uncover some difference in the gene content related to cell growth of the four Vibrio strains FA1, FA2, FA3, and ATCC 14048, which may explain growth superiority of the isolated strains. It is noted that there are more copies of several genes related to the DNA replication in the FA2 genome than in the other compared Vibrio strains. Furthermore, the genes responsible for amino synthesis are found, such as asD, within strains FA1 and FA2. Gene cluster cadABC, which relates to cell adaptation at acidic pH, only exists in strains FA1, FA2, and FA3. Finally, the wide spectra of substrates and genetic operability of these three isolated Vibrio strains are initially verified. This study provides excellent candidates for the development of next‐generation fast‐growing microbial workhorses, which may be very useful in synthetic biology.