bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social, ethical and behavioural aspects of COVID-19
Authors: Pan-ngum Wirichada , Poomchaichote Tassawan , Cuman Giulia , Cheah Phee-Kheng , Waithira Naomi , Mukaka Mavuto , Naemiratch Bhensri , Kulpijit Natinee , Chanviriyavuth Rita , Asarath Supa-at , Ruangkajorn Supanat , Silan Margherita , Stoppa Silvia , Zuanna Gianpiero Della , Ongkili Darlene , Cheah Phaik Kin , Osterrieder Anne , Schneiders Mira , Mackworth-Young Constance R.S. , Cheah Phaik Yeong 
Published: May 2020

Introduction: Vaccines and drugs for the treatment and prevention of COVID-19 require robust evidence generated from clinical trials before they can be used. Decisions on how to apply non-pharmaceutical interventions such as quarantine, self-isolation, social distancing and travel restrictions should also be based on evidence. There are some experiential and mathematical modelling data for these interventions, but there is a lack of data on the social, ethical and behavioural aspects of these interventions in the literature. Therefore, our study aims to produce evidence to inform (non-pharmaceutical) interventions such as communications, quarantine, self-isolation, social distancing, travel restrictions and other public health measures for the COVID-19 pandemic. Methods: The study will be conducted in the United Kingdom, Italy, Malaysia and Thailand. We propose to conduct 600-1000 quantitative surveys and 25-35 qualitative interviews per country. Data collection will follow the following four themes: (1) Quarantine and self-isolation (2) social distancing and travel restrictions (3) wellbeing and mental health (4) information, misinformation and rumours. In light of limitations of travel and holding in-person meetings, we will use online/remote methods for collecting data. Study participant will be adults who have provided informed consent from different demographic, socio-economic and risk groups. Discussion: At the time of writing, United Kingdom, Italy, Malaysia and Thailand have initiated strict public health measures and varying degrees of “lockdowns” to curb the pandemic. It is anticipated that these public health measures will continue in some countries (e.g. Italy, Malaysia) or be tightened further in other countries (e.g. Thailand, UK) to control the spread of the disease in the coming weeks and months. The data generated from our study could inform these strategies in real time.
Does Reciprocity Affect Analysts’ Incentives to Release Timely Information? Evidence from Syndication Relationships in Securities Underwriting
Authors: Mao Connie X. , Song Wei-Ling 
Published: May 2020

Reciprocity is a subtle but influential factor in maintaining business relationships. We examine the stock recommendations, earnings forecasts, and target prices issued by “reciprocity-pressured” analysts affiliated with securities underwriters who rely on other major underwriters’ invitations to be in syndicates. Consistent with the reciprocal pressure hypothesis, we find that reciprocity-pressured analysts delay releasing negative information on other major underwriters’ clients despite the fact that these analysts’ affiliated underwriters do not receive fees from those clients. We also document temporary retaliation by major underwriters when reciprocity-pressured analysts deviate from such expected reciprocity. The results suggest that reciprocal pressure in the investment banking industry has a real effect on analyst information dissemination. This paper was accepted by Suraj Srinivasan, accounting.
The relationship between nurses' knowledge and self-confidence in implementing palliative care in an intensive care unit
Authors: Kurnia Theresia Avila , Trisyani Yanny , Prawesti Ayu 
Published: May 2020

Background: This quantitative study aimed to analyse the relationship between knowledge and nurses' self-confidence (or self-efficacy) in applying palliative care (PC) in the intensive care unit (ICU). This study was a correlational study with a cross-sectional approach. The sampling technique used was total sampling, and the sample included all nurses who were actively working at the general hospital in Bandung, West Java, Indonesia, during the study. There were 127 people in total. Data were collected using questionnaires. The Pearson correlation test was used for bivariate analysis. The results of univariate analysis showed that the majority of respondents had high self-confidence but had less knowledge related to PC in the ICU. Based on the results of the bivariate analysis, there was a significant relationship between knowledge and self-confidence variables. The results showed that a high number of respondents had less knowledge in implementing PC in the ICU. Therefore, familiarisation sessions and training related to this are needed, focusing on nurses' beliefs in their abilities.
Monitoring respiratory rate in adults
Authors: Hill Barry , Annesley Sarah H. 
Published: May 2020

Barry Hill and Sarah H Annesley discuss the importance of monitoring respiratory rate and why it is a crucial clinical skill This article will introduce Respiratory Rate and the role of adequate respiration, as well as explore respiratory rate monitoring as an essential aspect of nursing care. It will also give rationale to the importance of respiratory rate monitoring as a clinical skill and introduce normal and abnormal respiration rates and patterns. Furthermore, it will provide a ‘how to’ guide on respiratory rate monitoring and use contemporary evidence-based literature to underpin respiratory rate monitoring for clinical practice.
Coral transplantation on a multilevel substrate of Artificial Patch Reefs: effect of fixing methods on the growth rate of two Acropora species
Authors: Munasik M , SABDONO AGUS , ASSYFA AZELIA N. , WIJAYANTI DIAH PERMATA , SUGIYANTO SUGIYANTO , IRWANI IRWANI , PRIBADI RUDHI 
Published: May 2020

Abstract. Munasik, Sabdono A, Assyfa AN, Wijayanti DP, Sugiyanto, Irwani, Pribadi R. 2020. Coral transplantation on a multilevel substrate of Artificial Patch Reefs: effect of fixing methods on the growth rate of two Acropora species. Biodiversitas 21: 1816-1822. Branching Acropora is generally used in coral transplantation to rehabilitate coral reefs. However, these corals are sensitive to environmental changes. Artificial Patch Reef (APR) is an artificial structure that provides a multilevel hard substrate. The purpose of the study was to investigate the effectiveness of the APR structure to facilitate the growth and survival of Acropora branching. Two species Acropora aspera and Acropora copiosa were transplanted vertically and horizontally on a modular concrete block in different levels of APR situated in the shallow reef of Panjang Island, Central Java. The results showed that the coral growth rate varied from 96.7 to 346.9 cm3/month, while survival ranged from 30 to 100% after 8 months. Lower survival rate mostly was found in the upper level of APR. The statistical analyses showed that the growth rate of A. copiosa fragment was significantly higher than that of A. aspera (p<0.05). Moreover, there were also significant differences in the treatments of transplantation method (p<0.05) to enhance coral growth. However, multilevel substrates were not significantly influenced by coral growth. This study suggested that A. copiosa which has high-level complexity in branching pattern will be selected to apply in shallow reef rehabilitation with transplanted vertically.
Identification of microplastics in a large water volume by integrated holography and Raman spectroscopy
Authors: Takahashi Tomoko , Liu Zonghua , Thevar Thangavel , Burns Nicholas , Mahajan Sumeet , Lindsay Dhugal , Watson John , Thornton Blair 
Published: May 2020

A noncontact method to identify sparsely distributed plastic pellets is proposed by integrating holography and Raman spectroscopy in this study. Polystyrene and poly(methyl methacrylate) resin pellets with a size of 3 mm located in a 20 cm water channel were illuminated using a collimated continuous wave laser beam with a diameter of 4 mm and wavelength of 785 nm. The same laser beam was used to take a holographic image and Raman spectrum of a pellet to identify the shape, size, and composition of material. Using the compact system, the morphological and chemical analysis of pellets in a large volume of water was performed. The reported method demonstrates the potential for noncontact continuous in situ monitoring of microplastics in water without collection and separation.
Single-shot intense few-cycle pulse interaction with polycrystalline ZnSe
Authors: Chai Yingjie , Yu Xiaoming , Cheng He , Chew Andrew , Chang Zenghu , Bass Michael , Soileau M. J. 
Published: May 2020

The interaction of high-intensity few-cycle laser pulses with solids opens a new area of fundamental light-material interaction research. The applied research extends from extreme nonlinearity in solids to the next-generation high laser light damage resistance optical design. In this Letter, 11 fs infrared, carrier-envelope-phase (CEP) stable, two-cycle laser pulses were applied to investigate the process of laser-material interaction on the ZnSe surface. A systematic study of a few-cycle pulse laser-induced damage threshold on ZnSe was performed for a single-pulse regime (1-on-1). Laser damage morphologies were carefully characterized. Our experiment demonstrated the very beginning of laser-induced structures on the ZnSe surface by using the shortest infrared few-cycle laser pulse currently available with a stable CEP.
Plasmonic nanojet: an experimental demonstration
Authors: Minin Igor V. , Minin Oleg V. , Glinskiy Igor A. , Khabibullin Rustam A. , Malureanu Radu , Lavrinenko Andrei V. , Yakubovsky Dmitry I. , Arsenin Aleksey V. , Volkov Valentyn S. , Ponomarev Dmitry S. 
Published: May 2020

We propose and study a microstructure based on a dielectric cuboid
placed on a thin metal film that can act as an efficient plasmonic
lens allowing the focusing of surface plasmons at the subwavelength
scale. Using numerical simulations of surface plasmon polariton (SPP)
field intensity distributions, we observe high-intensity subwavelength
spots and formation of the plasmonic nanojet (PJ) at the
telecommunication wavelength of 1530 nm. The fabricated microstructure
was characterized using amplitude and phase-resolved scattering-type
scanning near-field optical microscopy. We show the first experimental
observation of the PJ effect for the SPP waves. Such a novel, to the
best of our knowledge, and simple platform can provide new pathways
for plasmonics, high-resolution imaging, and biophotonics, as well as
optical data storage.
Relativistic near-single-cycle optical vortex pulses from noble gas-filled multipass cells
Authors: Cao Huabao , Nagymihaly Roland S. , Kalashnikov Mikhail 
Published: May 2020

We propose to obtain relativistic near-single-cycle optical vortices carrying orbital angular momentum through the post-compression of Laguerre–Gaussian pulses in gas-filled multipass cells. Our simulations revealed that 30 fs optical vortex pulses centered around 800 nm with a pulse energy of millijoule level can be compressed to near-single-cycle duration with topological charges from 1 to 20 within an argon-filled cell with five passes. The spectral broadening preserves the topological charge of the input beam; the spatio-spectral couplings are also discussed. The energy of the vortex pulses could be scaled up by increasing the dimensions of the cell. The relativistic near-single-cycle vortices are of great interest for the generation of ultrashort helical electron bunches based on hybrid electron acceleration in underdense plasmas and on isolated relativistic extreme ultraviolet optical vortices from high-order harmonic generation in solid foils.
The Effect of Islamic Attributes and Destination Affective Image on the Reputation of the Halal Tourism Destination of Jakarta
Authors: WIDJAJA Yunni Indrani , KHALIFA Gamal S. A. , ABUELHASSAN Abuelhassan Elshazly 
Published: May 2020

Tourism industry recognizes the growing interest in Halal tourism from both the perspectives of practitioners and researchers. Indonesia was chosen as the world's best halal tourism destination this year according to the 2019 Global Muslim Travel Index (GMTI) and outperformed 130 destinations from around the world. Among the 10 most favorite halal tourism destinations, Jakarta has the most unique characteristics compared to the other nine provinces. Related to this background, this study aims to examine the effect of Islamic attributes and destination affective image on the reputation of the halal tourism destination of Jakarta.
The research design outlines the use of quantitative research approaches. The unit of analysis and observation is International Muslim tourists who visited Jakarta. The Central Statistics Bureau (BPS) recorded the number of foreign visitors arriving DKI Jakarta amounted to 2,313,742 people at 2013. Hair et al. (1992) suggest the minimum sample size for SEM analysis is 100 to 200. So based on this opinion, this study will take a sample of 200, in accordance with the terms of use of SEM (Structural Equation Modeling) as analytic tools to test the hypotheses. The study was conducted in the cross-section period of 2019.
The results showed that the Islamic Attributes and Destination Affective Image affect the Destination Reputation. Destination reputation is more dominantly built by destination affective image compared to Islamic attributes. This finding has implications for related stakeholders that the development of destination affective image needs to be prioritized to support Jakarta's destination reputation as one of the halal tourism destinations in Indonesia. It mainly concerns on the aspects of natural and cultural resources, security, night life and entertainment, accessibility, and quality / price ratio.
The Supply Chain Resources in Job Performance on Hospitality and Tourism Sector
Authors: NORMI Siti 
Published: May 2020

Using 110 respondent’s hospitality and tourism service employees as the sample in Berastagi hospitality and tourism area in Karo Regency, North Sumatera. Data which is obtained were analyzed by using “analysis of the path”. The result of research is: the impact direct of discipline and significant on job satisfaction, discipline has an the impact direct on job performance, job promotion has an the impact direct on job performance, job satisfaction has an the impact direct on job performance, discipline has an the impact direct on job performance without through job satisfaction, and job promotion not has an the impact direct on job performance through job satisfaction, and job promotion not has an the impact direct on job performance through job satisfaction for hospitality and tourism service employees in Berastagi hospitality and tourism area in Karo Regency, North Sumatera.
Differential migration-related gene expression and altered cytokine secretion in response to serum starvation in cultured MDA-MB-231 cells
Authors: Ahmadiankia Naghmeh , Bagheri Mehdi , Fazli Mozhgan 
Published: May 2020

Abstract

Background
Serum starvation is mostly considered as a standard preparatory method in many cellular and molecular experiments. However, recent studies give some evidence that serum starvation is a major event that triggers various cell responses and has therefore great potential to change and interfere with the experimental results. In this study, the behavior of breast cancer cells in serum-starved condition was examined.

Objective
To focus on the role of serum starvation on cell migration and also the possible changes in the expression and secretion of genes and cytokines mostly involved in migration and chemotaxis of breast cancer cells.

Methods
MDA-MB-231 cells were cultured under serum-starved condition. Transwell migration assay was performed to evaluate the effect of serum starvation on cell migration after 24, 48, and 72 h. The transcriptional expression of migration-related genes was evaluated using real-time polymerase chain reaction. The cytokine secretion was also analyzed using enzyme-linked immunosorbent assay.

Results
Serum starvation suppressed cell migration in breast cancer cells. Additionally, the gene expression of markers involved in migration including β-catenin, twist, zinc finger E-box binding homeobox 1, vimentin, fibronectin, intercellular adhesion molecule 1, and vascular endothelial growth factor were downregulated. Moreover, cytokines of transforming growth factor, beta 1, matrix metallopeptidase 9, interleukin 8, and nitric oxide were differentially secreted.

Conclusions
Serum deprivation causes significant changes in cancer cell migration and also the expression of migration-related genes and cytokines, special care needs to be taken when this practice is used as preparatory method especially in migration and chemotaxis experiments on cancer cells.
(2E)-2-Benzylidene-4,7-dimethyl-2,3-dihydro-1H-inden-1-one (MLT-401), a novel arylidene indanone derivative, scavenges free radicals and exhibits antiproliferative activity of Jurkat cells
Authors: Rajagopalan Prasanna , Chandramoorthy Harish C. 
Published: May 2020

Abstract

Background
The arylidene indanone scaffold has contributed many lead molecules in chemotherapeutic anticancer agent research.

Objectives
To determine the oxidant-scavenging activities and antiproliferative activity of (2E)-2-benzylidene-4,7-dimethyl-2,3-dihydro-1H-inden-1-one (MLT-401), an arylidene indanone derivative.

Methods
Jurkat cells, primary lymphocytes, and Vero cells were treated with MLT-401. Antioxidant properties of MLT-401 were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH)-based, 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS)-based, and ferric-reducing antioxidant potential (FRAP) assays. Inhibition of cell proliferation was determined using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide-based assay. Nuclear status was determined using a DNA fragmentation assay, and cell cycle stage was analyzed by flow cytometry. Mitochondrial membrane enzyme activities were measured using colorimetric methods.

Results
The antioxidant assays gave MLT-401 half maximal inhibitory concentration (IC50) values of 1611 nM (DPPH-based assay), 2115 nM (ABTS-based assay), and 1586 nM (FRAP assay). MLT-401 inhibited proliferation of Jurkat cells with a concentration for 50% of maximal inhibition of cell proliferation (GI50) of 341.5 nM, being 12- and 9-fold less than GI50 concentrations for normal lymphocytes and Vero cells, respectively. MLT-401 caused nuclear fragmentation and DNA laddering as seen by electrophoresis. Jurkat cells showed a time-dependent accumulation of sub G0/G1 cells after MLT-401 treatment. Mitochondrial membrane-bound Na+/K+ ATPase, Ca2+ ATPase, and Mg2+ ATPase activities were inhibited by MLT-401 in a dose-dependent manner.

Conclusion
MLT-401 possesses significant antiproliferative activity and scavenges free radicals released through mitochondrial membrane damage in a Jurkat cell line model of cancer cells. Further investigation of MLT-401 as a chemotherapeutic anticancer agent and development of other arylidene indanone analogues are warranted. A detailed elucidation of mechanistic pathways is required for further development.
Chemical composition, antioxidant, anti-inflammatory and antiproliferative activities of the essential oil of Cymbopogon nardus, a plant used in traditional medicine
Authors: Bayala Bagora , Coulibaly Ahmed Y , Djigma Florencia W. , Nagalo Bolni Marius , Baron Silvère , Figueredo Gilles , Lobaccaro Jean-Marc A. , Simpore Jacques 
Published: May 2020

AbstractObjectivesNatural products commonly used in traditional medicine, such as essential oils (EOs), are attractive sources for the development of molecules with anti-proliferative activities for future treatment of human cancers, e.g., prostate and cervical cancer. In this study, the chemical composition of the EO from Cymbopogon nardus was characterized, as well as its antioxidativeproperties and anti-inflammatory and antiproliferative activities on LNCaP cells derived from prostate cancer.MethodsThe chemical composition of the EO was determined by GC/FID and GC/MS analyses. The antioxidative properties were assessed using DPPH radical scavenging assay and ABTS+• radical cation decolorization assay, and the anti-inflammatory capacity was determined by the inhibition of the lipoxygenase activity. Antiproliferative activity was evaluated by MTT assay.ResultsCollectively, our data show that the major constituents of C. nardus EO are citronellal (33.06 %), geraniol (28.40 %), nerol (10.94 %), elemol (5.25 %) and delta-elemene (4.09 %). C. nardus EO shows modest antioxidant and anti-inflammatory activity compared to the standard galic acid. C. nardus EO exhibits the best antiproliferative activity on the prostate cancer cell line LNCaP with an IC50 of 58.0 ± 7.9 μg/mL, acting through the induction of the cell cycle arrest.ConclusionsThis study has determined that C. nardus EO efficiently triggers cytotoxicity and pens a new field of investigation regarding the putative use of this EO in vivo.
Association of TNF-α-308G/A and IL-18 Polymorphisms with risk of HPV infection among sexually active women in Burkina Faso
Authors: Traore Ina M. A. , Zohoncon Théodora M. , Djigma Florencia W. , Compaore T. Rebeca , Traore Yves , Simpore Jacques 
Published: May 2020

AbstractHuman papillomavirus (HPV) infection is the most common sexually transmitted infection worldwide. Persistence infection can lead to the development of cervical cancer potentially due to some genetic factors such as polymorphisms in regulatory and coding regions of cytokine genes. The purpose of this study was to determine whether there is a relationship between TNF-308 G/A or IL18 polymorphisms and high-risk HPV infection among sexually active women from Burkina Faso. Ninety-one HPV infected and two hundred and nine HPV negative women (the latter used as healthy controls) were screened. TNFA-308 G/A and IL18-607 C/A polymorphisms were detected using the TaqMan allelic discrimination. HPV 52 (21.19%), HPV 39 (11.86%) and HPV 33 (11.02%) were the most common HPV genotypes. The TNFA-308A and IL18-607 C alleles were predominant in all women in the study. None of the TNFA and IL18 alleles were associated with HPV infection. The results suggest that there is no relationship between TNF-308 G/A or IL18-607C/A polymorphisms and HPV infection among women in the study.