bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Laba Terhadap Likuiditas Perusahaan
Authors: Supriadi Yoyon , Gendalasari Gen Gen 
Published: February 2020

Each company established course aims to derive a profit or benefit that can be used for the welfare of the company owners or shareholders. In every company liquidity is an important part of measuring the extent to which companies are able to pay maturing obligations to its creditors. Liquidity is a measure of investor decision-making, in which investors learn the level of liquidity and profitability in order to take the right decision for the future. Through this research are expected to know how the liquidity of the company if it is in accordance with the standard value of liquidity compared with the same company with a view of the profit, if not then impact whether and how the best solution which can be given to the company. Regression coefficient PT. Medco Energi International Tbk shows that Return On Assets (ROA) has a positive effect on the current ratio. The result of F test for the company showed no significant effect between Return On Assets (ROA) of the current ratio, this is because there are other factors that affect the current ratio. PT. Medco Energi International has a significant effect between Return On Assets (ROA) on the current ratio.

Keywords : Return, Liquidity, Profit.
Pengaruh Atribut Produk Herbal Terhadap Kepuasan Pelanggan
Authors: Sad Raden Irwan , Sukartaatmadja Iswandi 
Published: February 2020

Given the company's product attributes can know how much the level of customer satisfaction the company's products. To that end, the company has its own unique way and in a typical product attributes that customers will feel satisfied when buying products. Marketing activities can be done by improving and providing innovation to the product will be in production. Where products are manufactured must have a good product attributes in accordance with customer expectations, and creating customer satisfaction. This study aims to know the attributes of Herbal Products manufactured by Raudhoh. To find out the customer satisfaction in taking Herbal Products from Raudhoh. To determine the effect of product attributes on customer satisfaction Herbal Products Brand Raudhoh Raudhoh on international companies. The results showed the customer satisfaction of international raudhoh herbal products is 9.781. The calculated value of the correlation coefficient of 0.676 is obtained which means that there is a significant relationship with the closeness of the relationship strong and positive relationship between product attributes to customer satisfaction. the results obtained from the coefficient of determination 0.457, which means that the community has a contribution of 45.7% in creating customer satisfaction, and the rest is influenced by other factors

Keywords: product attributes, customer satisfaction
The Nature of the Double Nuclei in the Barred S0 Galaxy IC 676
Authors: Zhou Zhimin , Ma Jun , Zhou Xu , Wu Hong 
Published: February 2020

Abstract
The lenticular galaxy IC 676 is a barred galaxy with double nuclei and active star formation in the central region. In this work we present the long-slit spectroscopy and archival multiwavelength images to investigate the nature and origin of the double nuclei in IC 676. Through photometric 1D brightness profiles and 2D image decomposition, we show that this galaxy consists of a stellar bar with the length of ∼2.5 kpc and two Sérsic disks both of which with Sérsic index n ∼ 1.3. There is probably little or no bulge component assembled in IC 676. The luminosities of the double nuclei are primarily dominated by young stellar populations within the ages of 1–10 Myr. The northern nucleus has stronger star formation activity than the southern one. The surface densities of the star formation rate in the double nuclei are similar to those in starburst galaxies or the circumnuclear star-forming regions in spiral galaxies. Each of the double nuclei in IC 676 likely consists of young massive star clusters, which can be resolved as bright knots in the Hubble Space Telescope high-resolution image. Our results suggest that IC 676 likely has a complex formation and evolutionary history. The secular processes driven by the stellar bar and external accretion may dominate the formation and evolution of its double nuclei. This indicates that the secular evolution involving the internal and external drivers may have an important contribution for the evolution of lenticular galaxies.
The Carnegie-Irvine Galaxy Survey. IX. Classification of Bulge Types and Statistical Properties of Pseudo Bulges
Authors: Gao 高 Hua 桦 , Ho Luis C. , Barth Aaron J. , Li Zhao-Yu 
Published: February 2020

Abstract
We study the statistical properties of 320 bulges of disk galaxies in the Carnegie-Irvine Galaxy Survey, using robust structural parameters of galaxies derived from image fitting. We apply the Kormendy relation to classify classical and pseudo bulges and characterize the bulge dichotomy with respect to the structural properties of the bulges and the physical properties of the host galaxies. We confirm previous findings that pseudo bulges on average have smaller Sérsic indices, lower bulge-to-total ratios, and fainter surface brightnesses than classical bulges. Our sizable sample statistically shows that pseudo bulges are more intrinsically flattened than classical bulges. Pseudo bulges are most frequent (incidence ≳80%) in late-type spirals (later than Sc). Our measurements support the picture in which pseudo bulges arose from star formation induced by inflowing gas, while classical bulges were born out of violent processes such as mergers and coalescence of clumps. We reveal differences with the literature that warrant attention: (1) the bimodal distribution of Sérsic indices presented by previous studies is not reproduced in our study; (2) classical and pseudo bulges have similar relative bulge sizes; and (3) the pseudo bulge fraction is considerably smaller in early-type disks than reported in previous studies based on one-dimensional surface brightness profile fitting. We attribute these differences to our improved image quality, more robust bulge-to-disk decomposition technique, and to the different classification criteria that we applied. Moreover, we find that barred galaxies do not host more pseudo bulges or more prominent pseudo bulges than unbarred galaxies. Various implications of these findings are discussed.
Leukocyte count: A reliable marker for the severity of organophosphate intoxication?
Authors: Kumar Sunil , Agrawal Sachin , Raisinghani Nitin , Khan Shameem 
Published: February 2020

ABSTRACT
INTRODUCTION: Organophosphorus poisoning (OPP) is a major public health problem in developing countries like India. Leukocyte count is a simple and inexpensive test, and elevated count is associated with acute inflammation and increased oxidative stress-like OPP. This study was done to correlate the severity of acute OPP with leukocyte count and also to assess the prognosis.
MATERIALS AND METHODS: A prospective, observational clinical study was done on 80 patients suspected of OPP of age >15 years admitted to emergency unit at a tertiary rural teaching health-care center of Central India. Serum cholinesterase level and leukocyte count were estimated at the time of admission in all patients and severity of OPP was assessed according to Peradeniya organophosphorus poisoning (POP) scale.
RESULTS: The mean age of the patients was 33.52 years (standard deviation [SD] 11.62) in males and 27.30 years (SD 7.33) in females. Among them, 57 (71.25%) were males and 23 (28.75%) were females. The severity of poisoning was directly correlated with serum cholinesterase level (P = 0.0001). Leukocyte count had a sensitivity of 60%, specificity of 76%, and negative predictive value of 85% if counts were more than 12,000 and 30% sensitivity, 95% specificity, and 80% negative predictive value if counts were more than 15,000 in predicting mortality in patients with OPP.
CONCLUSION: Leukocyte count levels on admission can be used a prognostic marker in patients with OP poisoning.
Sigma metrics as a tool for evaluating the performance of internal quality control in a clinical chemistry laboratory
Authors: Kumar B. Vinodh , Mohan Thuthi 
Published: February 2020

Abstract
OBJECTIVE: Six Sigma is one of the most popular quality management system tools employed for process improvement. The Six Sigma methods are usually applied when the outcome of the process can be measured. This study was done to assess the performance of individual biochemical parameters on a Sigma Scale by calculating the sigma metrics for individual parameters and to follow the Westgard guidelines for appropriate Westgard rules and levels of internal quality control (IQC) that needs to be processed to improve target analyte performance based on the sigma metrics.
MATERIALS AND METHODS: This is a retrospective study, and data required for the study were extracted between July 2015 and June 2016 from a Secondary Care Government Hospital, Chennai. The data obtained for the study are IQC - coefficient of variation percentage and External Quality Assurance Scheme (EQAS) - Bias% for 16 biochemical parameters.
RESULTS: For the level 1 IQC, four analytes (alkaline phosphatase, magnesium, triglyceride, and high-density lipoprotein-cholesterol) showed an ideal performance of ≥6 sigma level, five analytes (urea, total bilirubin, albumin, cholesterol, and potassium) showed an average performance of <3 sigma level and for level 2 IQCs, same four analytes of level 1 showed a performance of ≥6 sigma level, and four analytes (urea, albumin, cholesterol, and potassium) showed an average performance of <3 sigma level. For all analytes <6 sigma level, the quality goal index (QGI) was <0.8 indicating the area requiring improvement to be imprecision except cholesterol whose QGI >1.2 indicated inaccuracy.
CONCLUSION: This study shows that sigma metrics is a good quality tool to assess the analytical performance of a clinical chemistry laboratory. Thus, sigma metric analysis provides a benchmark for the laboratory to design a protocol for IQC, address poor assay performance, and assess the efficiency of existing laboratory processes.
Value of cytokeratin-19, Hector Battifora mesothelial-1 and galectin-3 immunostaining in the diagnosis of thyroid neoplasms
Authors: Sanuvada Rajasekhar , Nandyala Rukmangadha , Chowhan Amit Kumar , Bobbidi Phaneendra , Yootla Mutheeswariah , Hulikal Narendra , Sachan Alok 
Published: February 2020

Abstract
BACKGROUND: Diagnosis of types and aggressiveness of thyroid cancers is difficult. The "gold standard" in diagnosis is using routine hematoxylin and eosin staining. Several markers have been investigated for differentiating them among which cytokeratin-19 (CK-19), Hector Battifora mesothelial cell (HBME-1), and galectin-3 are found to be most commonly used. Most studies have evaluated the single expression of markers in various thyroid lesions.
AIMS AND OBJECTIVES: To know the value of immunohistochemical expression of CK-19, HBME-1, and galectin-3 in diagnosing thyroid neoplasms. To study the expression and compare the results of HBME-1, CK-19, and galectin-3 immunohistochemical markers in histopathologically diagnosed malignant lesions and nonmalignant lesions and demonstrate their usefulness in differentiating them.
MATERIALS AND METHODS: A prospective study was carried out on thyroidectomy specimens sent in 10% buffered formalin to Department of Pathology, SVIMS, Tirupati, from May 2013 to August 2014. Sensitivity and specificity for each marker and their combination in diagnosis were calculated.
RESULTS: Among 120 cases, nonmalignant lesions were 70 (58.33%) and malignant lesions 50 (41.67%). Among nonmalignant lesions, 65 (93%) were adenomatous goiter and 5 (7%) were follicular adenomas. In malignant lesions, 48 (96%) were papillary carcinoma and 1 (2%) each of follicular carcinoma and anaplastic carcinoma. Among papillary carcinomas, classical were 26 (54.16%) followed by 17 follicular variant (35.41%). Galectin-3 had highest sensitivity of 90% and HBME-1 had highest specificity of 97.14%.
CONCLUSIONS: Panel of HBME-1+ galectin-3 or CK-19, HBME-1, and galectin-3 increase the accuracy of diagnosis in histopathologically difficult cases.
Occurrence of bla genes encoding carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii from Intensive Care Unit in a tertiary care hospital
Authors: Subramaniyan Jayanthi Siva , Sundaram Jeya Meenakshi 
Published: February 2020

Abstract
CONTEXT: ICU shows increasing incidence of infection associated with the use of invasive procedures for the diagnostic purpose as well as the indiscriminate use of antibiotics. Pseudomonas aeruginosa and Acinetobacter species are "very successful" pathogen and the emergence of the Metallo-β-Lactamases (MBL) is becoming a therapeutic challenge.
AIMS: To isolate the Nonfermenting Gram negative bacilli from the ICU samples. To identify the metallo betalactamase producers and to detect the bla gene presence among the Pseudomonas aeruginosa and Acinetobacter baumannii.

SETTINGS AND DESIGN: The Nonfermenting Gram negative bacilli isolates from the ICU samples were taken over for 5 years (2009-2014) in a tertiary care hospital.
METHODS AND MATERIALS: The isolates of Pseudomonas species and Acinetobacter species were confirmed by API analyser and processed according to standard procedures. Detection of the MBL producers were done by E strip method and subjected for bla gene detection by PCR method.
RESULTS: In our study a total of 195 isolates of NFGNB were obtained from various ICU. Of these MBL producers, 26 % were Pseudomonas aeruginosa and 25 % were Acinetobacter baumannii. The subtypes of bla
VIMMBL producing P.aeruginosa were 26%.The predominant gene coding for MBL activity in A.baumannii were found to be bla
OXA gene 11.9%. The gene accession numbers were KF975367, KF975372.
CONCLUSIONS: We have to control the development and dissemination of these superbugs among the ICU's.
HBG2 -158 (C>T) polymorphism and its contribution to fetal hemoglobin variability in Iraqi Kurds with beta-thalassemia minor
Authors: Albarawi Dilan J. , Balatay Amer A. , Al-Allawi Nasir 
Published: February 2020

ABSTRACT
PURPOSE: Hemoglobin (Hb) F% is increased in up to half of beta-thalassemia (β-thal) carriers. Several polymorphisms have been linked to such variability in different populations, including HBG2 - 158(C>T) (Xmn I polymorphism) on chromosome 11. To determine the role of this polymorphism in such variability among Iraqi Kurds, the current study was initiated.
MATERIALS AND METHODS: A total of 102 consecutive patients diagnosed as β-thal minor were enrolled. The enrollees had their diagnosis based on peripheral blood counts and high-performance liquid chromatography to determine HbA2 and HbF. All enrollees had their DNA extracted by phenol-chloroform method and Xmn I polymorphism detected by restriction fragment length polymorphism-polymerase chain reaction.
RESULTS: The mean age (standard deviation [SD]) of the 102 enrollees was 25.4 (14.0) years, and the enrollees included 48 males and 54 females. Xmn I polymorphism was identified in heterozygous state in 46 (45.1%) patients and in homozygous state in one patient (0.98%). Thus, the minor allele frequency of this polymorphism was 0.235 in the studied group. There were no significant differences in red cell indices and HbA2% in carriers of the minor allele compared to noncarriers, while HbF% and absolute HbF concentrations were significantly higher in the former subgroup (P = 0.032 and 0.014, respectively). This polymorphism's contribution to HbF variability was found to be 5.8% in the studied sample. Furthermore, those with HbF ≥2% were 3.2 folds more likely to carry the minor allele.
CONCLUSIONS: Xmn I polymorphism is frequently encountered in Iraqi Kurds with β-thal minor, and it is significantly associated with higher fetal hemoglobin in these patients.
Diagnostic challenges of tubercular lesions of breast
Authors: Jairajpuri Zeeba Shamim , Jetley Sujata , Rana Safia , Khetrapal Shaan , Khan Sabina , Hassan Mohammad Jaseem 
Published: February 2020

ABSTRACT
INTRODUCTION: Tuberculosis (TB) in the developing countries presents with both pulmonary and extrapulmonary manifestations. Breast TB, however, remains a rare presentation. Its importance lies in the fact that it may mimic malignancy or present as inflammatory lump/abscess.
AIMS AND OBJECTIVE: The aim of the present study is to highlight the importance of breast TB and its diagnostic challenges.
MATERIALS AND METHODS: It was a retrospective study conducted at a tertiary care hospital, over 2 years between 2013 and 2015 during which eight cases of breast lesions were diagnosed as of tubercular origin.
RESULTS: Granulomas were seen in five cases while three cases revealed only few epithelioid cells, and necrosis was seen in all cases on fine-needle aspiration cytology. Histopathological evaluation was available in six out of the eight cases, while acid–fast bacilli were positive in three cases, the characteristic granulomas were seen in all the six cases evaluated.
CONCLUSION: Significance of TB breast lies in the fact that it may masquerade as breast malignancy or pyogenic abscess. India is a developing country where TB is endemic, a high index of suspicion should be expressed in evaluating breast masses, and TB should be considered in the differential diagnosis.
Prevalence of blaKPC and its occurrence with other beta-lactamases in Klebsiella pneumoniae
Authors: Remya Poothakuzhiyil , Shanthi Mariappan , Sekar Uma 
Published: February 2020

ABSTRACT
BACKGROUND: Klebsiella pneumoniae (K. pneumoniae) is an important nosocomial pathogen, and the emergence of multidrug resistance in these organisms limits the treatment options for serious infections caused by them. K. pneumoniae carbapenemase (KPC) is one of the clinically significant Class A beta-lactamases.
AIM AND OBJECTIVE: This study was aimed to detect the KPC and its coexistence with other beta-lactamases in K. pneumoniae.
MATERIALS AND METHODS: A total of 370 isolates, collected over a period of 1 year, were included in this study. The source of these isolates were urine (n = 170), exudative specimens (n = 132), respiratory secretions such as bronchial wash, endotracheal aspirate, and pleural fluid (n = 38), and blood (n = 30). For all the isolates, antibiotic susceptibility tests by disc diffusion, modified Hodge test, and KPC screening test were done. Polymerase chain reaction (PCR) was performed for the detection of KPC and the copresence of other beta-lactamases genes.
RESULTS: Among the 370 isolates, 41 were resistant to the carbapenem by disc diffusion and minimum inhibitory concentration tests. Screen test using ertapenem and the boronic acid disk was positive in 14 isolates. Only one isolate harbored KPC gene by PCR, and it was co-produced with SHV-12 and CTX-M-15.
CONCLUSION: PCR remains the gold standard for detection of KPC compared with any other phenotypic methods. Early detection of these genes helps in initiating proper antibiotic treatment.
Tuberculosis cutis orificialis with underlying pulmonary tuberculosis in an immunocompetent man
Authors: Dey Biswajit , Deshpande Archana Hemant , Bhat Sanjeev Hosdurg , Singh Ashok 
Published: February 2020

ABSTRACTTuberculosis cutis orificialis (TCO) is a rare form of tuberculosis more often secondary to pulmonary tuberculosis. TCO has varied differential diagnoses and thus results in delayed diagnosis and treatment leading to serious consequences. The diagnosis of TCO is confirmed by biopsy and nucleic acid amplification tests in majority of cases. We report a case of TCO with underlying pulmonary tuberculosis in a 50-year-old male, who presented with a painful nonhealing ulcer of the right buccal mucosa. Biopsy and real-time polymerase chain reaction helped in confirming the diagnosis. The patient was treated with antitubercular therapy.
Molecular characterization and antimicrobial susceptibility profile of New Delhi metallo-beta-lactamase-1-producing Escherichia coli among hospitalized patients
Authors: Agarwal Anjali , Srivastava Jyoti , Maheshwari Ujjwal , Iftikhar Mohd 
Published: February 2020

ABSTRACT
BACKGROUND: Carbapenemase-producing microorganisms are becoming a major concern among hospital-acquired infections. There is also increased multidrug resistance seen among these isolates.
AIMS: We have conducted this study to determine the prevalence of New Delhi metallo-beta-lactamase-1 (NDM-1) gene-producing Escherichia coli among hospitalized patients in a tertiary care hospital in Northern India.
SETTINGS AND DESIGN: The study was conducted in the Department of Microbiology with the tertiary care hospital settings. It was a prospective cross-sectional observational study conducted during January 2014–August 2014.
MATERIALS AND METHODS: A total of 500 nonduplicate E. coli samples were processed. The isolates with reduced susceptibility to ertapenem, i.e., zone diameter between 19 and 21 mm, were considered carbapenemase producers. These isolates were subjected to modified Hodge test for phenotypic confirmation. Polymerase chain reaction was performed on all the screened isolates for molecular detection of NDM-1 gene.
STATISTICAL ANALYSIS USED: Chi-square test was used to analyze the data and P < 0.05 was considered statistically significant.
RESULTS: Out of 500 E. coli isolates, 61 (12.2%) were screened for carbapenemase production. 47 (9.4%) isolates were positive by modified Hodge test and 36 (7.2%) isolates showed the presence of blaNDM-1 gene (P < 0.05).
CONCLUSION: There is an increased prevalence of NDM-1 gene-producing E. coli isolates. These carbapenemase-producing isolates are more resistant to other group of antibiotics (aminoglycosides, fluoroquinolones along with β-lactam group). Early detection of blaNDM-1 gene can help in choosing the effective treatment options for hospitalized patients in time, thereby reducing the risk of mortality.
Prevalence, etiology, and antibiotic resistance profiles of bacterial bloodstream infections in a tertiary care hospital in Northern India: A 4-year study
Authors: Khurana Surbhi , Bhardwaj Nidhi , Kumari Minu , Malhotra Rajesh , Mathur Purva 
Published: February 2020

Abstract
INTRODUCTION: Bloodstream infections (BSIs) can lead to life-threatening sepsis and are globally associated with high morbidity and mortality. Although BSIs require immediate antimicrobial treatment, their prevalence, etiology, and antimicrobial susceptibilities differ from one country to other. There is a dearth of such data from India. Here, we report the 4-year etiologic data on BSI in trauma patients admitted to a tertiary care referral hospital in New Delhi, India.
MATERIALS AND METHODS: A retrospective study was conducted at the trauma center between January 2013 and December 2016. The routine microbiological data on bacterial BSI were recorded and determined retrospectively from the laboratory records. Antimicrobial susceptibility profiles were statistically analyzed.
RESULTS: A total of 2017 bacterial strains isolated from blood culture samples were included for microbiological analysis. During the study, the median age of the patients varied from 30 to 35 years, with the percentage of females in the study population varying from 17% to 19%. The predominant pathogens were Gram-negative bacteria, with Acinetobacter species, followed by Klebsiella species being the most commonly isolated organisms throughout the 4 years of study. Among Gram-positive isolates, Staphylococcus species were the leading pathogens (11%–15%).
CONCLUSIONS: A detailed analysis of prevalence, etiology of BSIs in India and its resistance profile is crucial for appropriate antibiotic use, clinical management, and formulation of antibiotic policies and preventive measures.