bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional Connectome Analyses Reveal the Human Olfactory Network Organization
Authors: Arnold T. Campbell , You Yuqi , Ding Mingzhou , Zuo Xi-Nian , de Araujo Ivan , Li Wen 
Published: May 2020

AbstractThe olfactory system is uniquely heterogeneous, performing multifaceted functions (beyond basic sensory processing) across diverse, widely distributed neural substrates. While knowledge of human olfaction continues to grow, it remains unclear how the olfactory network is organized to serve this unique set of functions. Leveraging a large and high-quality resting-state functional magnetic resonance imaging (rs-fMRI) dataset of nearly 900 participants from the Human Connectome Project (HCP), we identified a human olfactory network encompassing cortical and subcortical regions across the temporal and frontal lobes. Highlighting its reliability and generalizability, the connectivity matrix of this olfactory network mapped closely onto that extracted from an independent rs-fMRI dataset. Graph theoretical analysis further explicated the organizational principles of the network. The olfactory network exhibits a modular composition of three (i.e., the sensory, limbic, and frontal) subnetworks and demonstrates strong small-world properties, high in both global integration and local segregation (i.e., circuit specialization). This network organization thus ensures the segregation of local circuits, which are nonetheless integrated via connecting hubs [i.e., amygdala (AMY) and anterior insula (INSa)], thereby enabling the specialized, yet integrative, functions of olfaction. In particular, the degree of local segregation positively predicted olfactory discrimination performance in the independent sample, which we infer as a functional advantage of the network organization. In sum, an olfactory functional network has been identified through the large HCP dataset, affording a representative template of the human olfactory functional neuroanatomy. Importantly, the topological analysis of the olfactory network provides network-level insights into the remarkable functional specialization and spatial segregation of the olfactory system.
Contractions of the C-Terminal Domain ofSaccharomyces cerevisiaeRpb1p Are Mediated by Rad5p
Authors: Stewart Taylor , Exner Alexandra E , Patnaik Paras , Fuchs Stephen M 
Published: May 2020

AbstractThe C-terminal domain (CTD) is an essential domain of the largest subunit of RNA polymerase II, Rpb1p, and is composed of 26 tandem repeats of a seven-amino acid sequence, YSPTSPS. Despite being an essential domain within an essential gene, we have previously demonstrated that the CTD coding region is genetically unstable. Furthermore, yeast with a truncated or mutated CTD sequence are capable of promoting spontaneous genetic expansion or contraction of this coding region to improve fitness. We investigated the mechanism by which the CTD contracts using a tet-off reporter system for RPB1 to monitor genetic instability within the CTD coding region. We report that contractions require the post-replication repair factor Rad5p but, unlike expansions, not the homologous recombination factors Rad51p and Rad52p. Sequence analysis of contraction events reveals that deleted regions are flanked by microhomologies. We also find that G-quadruplex forming sequences predicted by the QGRS Mapper are enriched on the noncoding strand of the CTD compared to the body of RPB1. Formation of G-quadruplexes in the CTD coding region could block the replication fork, necessitating post-replication repair. We propose that contractions of the CTD result when microhomologies misalign during Rad5p-dependent template switching via fork reversal.
Unilateral buccal space masses: a case series
Authors: Kumar Mathangi , Kudva Adarsh , Vineetha Ravindranath , Solomon Monica 
Published: May 2020

The head and neck region consists of several potential tissue spaces that are formed by the fascial layer. The buccal space is an area of anatomic significance due to its small size and distribution of adipose tissue. Unilateral buccal space masses often pose a diagnostic challenge owing to the diversity of tissues in the area. Here, we report four such cases of buccal space masses arising from different tissues, which presented as unilateral buccal space swelling. This report also highlights the various causes and the differential diagnoses of unilateral buccal space masses.
Praksisnære profesjonssamtaler med studenter i barnehagelærerutdanningen
Authors: Fjellanger Liv Ingrid , Halland Sissel , Nordlie Randi , Winje Annette 
Published: May 2020

Artikkelen retter søkelyset mot hvilke kjennetegn som preger de formelle profesjonsinnrettede profesjonssamtalene med førsteårsstudenter i en barnehagelærerutdanning i Norge. Målet med samtalene er å bidra til barnehagelærerstudentenes profesjonsinnretting. Metodisk hviler studien på aksjonsforskning, men det er datamateriale fra fokusgruppesamtaler med barnehagelærerstudenter og pedagogikklærere som danner grunnlaget for denne artikkelen. Analysen viser at samtalene er preget av nærhet og støtte, spor av utfordringer og ønske om bekreftelser. Dette indikerer noen utfordringer, men også noen muligheter, som kan ligge i profesjonssamtalen med tanke på å fremme studentenes profesjonsinnretting. Funnene drøftes i lys av profesjons, - kommunikasjons, - og veiledningsteori.
Competencias administrativas en la calidad del servicio en las instituciones educativas del nivel inicial
Authors: Núñez Lira Luis Alberto , Giordano Silva Marisol Verónica , Menacho Vargas Isabel , Uribe Hernández Yrene Cecilia , Rodríguez Fuentes Luis 
Published: May 2020

Se buscó determinar la influencia de las competencias administrativas desarrolladas en las directoras sobre la calidad del servicio educativo que ofrecen las instituciones educativas del nivel inicial en la Unidad de Gestión Local 07, Perú. Esta investigación se enmarca dentro del modelo positivista y de tipo básica-sustantiva, con nivel explicativo y de diseño transversal y no experimental. Fueron 155 docentes del nivel inicial que conformaron una muestra probabilística, aleatoria simple; se aplicaron dos escalas de opinión o percepción como instrumentos para la recolección de datos cuya validez y confiabilidad fueron establecidas previamente; los datos fueron procesados estadísticamente mediante el análisis de regresión. Se halló que el 71,3% de las profesoras de inicial percibían que en las directoras de las Instituciones Educativas de nivel Inicial del distrito habían desarrollado las competencias administrativas y que el 85% de las profesoras de inicial perciben que el servicio que brindan en su escuela es de alta calidad y para el 12,5% el servicio es de calidad, concluyéndose que la influencia de las capacidades administrativas de las directoras fue del 45,63% y sobre la percepción de alta calidad en el servicio que se brinda en las instituciones educativas del nivel inicial de la UGEL 07.
PENGGUNAAN GOOGLE TRANSLATE DALAM PENERJEMAHAN TEKS BAHASA ARAB KE DALAM BAHASA INDONESIA
Authors: Faqih Ahmad 
Published: May 2020

This research was conducted to overcome the problems faced by academics on the difficulty of understanding Arabic texts with the application of Google Translate. Through qualitative descriptive methods, data obtained by interviews and questionnaires. Then data is collected which finally found various problems. Departing from these problems, the data are analyzed to find solutions to overcome them. From the results of the study found a solution, namely there need to be several steps that can be used as a guide so that the translation results are commensurate in the target language. These steps are (1) enter the whole text into the machine; (2) copy the translated text into Microsoft words; (3) read the entire equivalent in the target text; (4) compile the target text according to the structure in the target language; and (5) looking for the right equivalent in accordance with the culture contained in the source language and target language.
PENGGUNAAN AL-LAGZU FÎ AL-JAWÂB DALAM AL-QUR’AN
Authors: Nugraha Inggo , Ali Mad 
Published: May 2020

This research article aims to describe the form of the expression al-lagzu fî al-jawâb in the Qur'an. Al-lagzu fî al-jawâb is a form of diverting the conversation to something more important. Al-lagzu fî al-jawâb is an art in balagah because it gives a beautiful impression on someone's conversation. This discussion of al-lagzu fî al-jawâb is not given a specific foundation by the scholars of balagah and the writers of the book in which discussing al-lagzu fî al-jawâb . The data source of this study was taken from the Qur'an. The object of his research is focused on the verses of al-lagzu fî al-jawâb contained in the Qur'an. The data is collected through documentation and recording format. Then the data were analyzed qualitatively. The results showed that there were eighty expressions of al-lagzu fî al-jawâb in the Qur'an. The phrase can be classified into four forms and six themes.
ANALYSIS OF MORPHOLOGY & HOUSING LAYOUT IN CIBADUYUT HANDYCRAFT CENTER IN CONTEXT TOWARD INTEGRATION WITH THE NEW SYSTEM OF TOD IN THE FUTURE
Authors: Yosita Lucy 
Published: May 2020

Abstract - The city development is should give positive contribution to social development, on ideal situation. However this situation is not always similar with the expectation as well as theory. Several factors are be as the push factor to the movement, and the movement can be contradictive to negative conditions: (1). The high level land invasion by private sector to community on location. (2). The lack of development as well as training program in location, by the government and others. (3). The condition of high pressure of import handycract from another country including : shoes and other handycraft from leather. The similar things happen in Cibaduyut as housing settlement based on leather industry-activity. An important thing that should be highlighted is this analysis based on the strength and the opportunity of application concept of “system approach to architecture” (Handler : (1970)), which being completed with many supporting theories. Comprehensive analysis of physical condition social as well as regulation, is as the key factor to find the best model as the design solution of redevelopment sustainable settlement as well as sustainable landscape development in research location. Hopefully the model will relevant with the planning of High Speed railway (HSRT) Bandung-Jakarta which will be finished on 2021. Keywords: Housing Layout, Housing Morphology, Transit Oriented Developmen (TOD), System Approach to Architecture, Sustainable Tourism Settlement.
Özel Durumlara Sahip Ebeveynlerin Doğum Sonrası Yeni Hayata Uyumları Ve Ebelerin Sorumlulukları
Authors: GÖKDUMAN KELEŞ Mine , TAŞPINAR Ayten , ALTINKAYA Özlem 
Published: May 2020

Doğum sonrası dönem; ebeveynler ve
bebekler için çok önemli bir süreçtir.
Özellikle özel durumlara sahip ebeveynler (engellilik, infertilite,
anomalili bebeği olan, istenmeyen gebelik, çoğul gebelik) doğum sonrası döneme
adaptasyon sağlamakta zorlanmaktadır. Engelli ebeveynlerin doğum sonu döneme
uyumları uzayabilirken, infertil ebeveynlerde doğum sonu dönemde postpartum
depresyon görülebilmekte ve anomalili bir bebeğe sahip olan ebeveynlerde
post-travmatik stres yaşayabilmektedir. İstenmeyen gebelik sonucu bebek sahibi
olan ebeveynlerde öfke, hayal kırıklığı, bebeği istememe gibi tepkiler
görülebilmekte, çoğul gebeliklerde
doğum sonrası psikolojik ve sosyal desteğe ihtiyaç duyulmaktadır.

Bu derleme özel
durumlara sahip ebeveynlerin doğum sonrası döneme adaptasyon süreçleri ile
ilgili ebe ve hemşirelere
farkındalık kazandırmak amacıyla hazırlanmıştır.
Prediction of the development of lipid distress syndrome in patients with a sustained response to antiviral therapy of chronic hepatitis C
Authors: Konstantinov Dmitry Yu. , Konnova Tatiana V. 
Published: May 2020

Aim. The purpose of the article is to devise the method for predicting the development of lipid distress syndrome in patients with a sustained response to antiviral therapy of chronic viral hepatitis C on the basis of clinical and laboratory data.
Materials and methods. The outcomes of lipid distress syndrome were studied in 235 patients with a sustained virological response to antiviral therapy of chronic hepatitis C during the follow-up period lasting from 1 to 10 years.
Results. From the perspective of the discriminative analysis of the data of the complex examination of 135 patients, we developed a discriminative model of predicting the development of lipid distress syndrome in patients with a sustained response to antiviral therapy of chronic hepatitis C. The cross-checking of the accuracy of prediction was carried out by the examination of other 100 patients.
Conclusion. Sensitivity, specificity, prognostic value of positive and negative prognostic results and the accuracy index of the developed discriminative model for predicting the development of lipid distress syndrome are equal to 100%.
PENGEMBANGAN MODUL FOKUSKY PARASITOLOGI PADA PROGRAM STUDI PENDIDIKAN BIOLOGI IKIP BUDI UTOMO MALANG
Authors: Mistianah Mistianah , Qomariyah Ismi Nurul 
Published: May 2020

This study aims to develop a focusky-based module on Paracytology course for Biology Education college students. The type of this research is Research Development (Research and Development). The development of focusky-based module uses the Research and Development (R & D) method with the 4 D model (Define, Design, Develop, and Dessiminate). This research starts from the define stage where at this stage identification of material concepts that must be contained in focusky-based module. Furthermore design the focusky-based module. After focusky-based module has been designed and created, the development stage is carried out, namely product validation by experts and product testing in the lecture process. The results showed that the validity of the material experts was in valid criteria with the percentage of paracytology modules of 89%, the results of validity by media experts were in valid criteria with the percentage of learning media as much as 88,25%. From the feasibility test, it was concluded that the module is included in the category very good.
LÜKS MARKALARDA SOSYAL MEDYA PAZARLAMASININ MARKA DEĞERİ VE SATIN ALMA NİYETİNE ETKİSİ, KİŞİLİK ÖZELLİKLERİNİN ROLÜ ÜZERİNE BİR ARAŞTIRMA
Authors: GÜZEL Işılay , YÜKSELEN Cemal 
Published: May 2020

Sosyal medya son yıllarda pazarlama alanının önemli bir ilgi odağı olmuştur. Markalar, geleneksel araçlarla birlikte sosyal medyada da konumlanıp pazarlama stratejilerini ve özelde de tutundurma eylemlerini bu platformlarda da uygulayarak hedef pazarlarına ulaşmaktadırlar. Marka yatırımları uzun dönemli ve büyük tutarlarda olan lüks markaların da bu platformlarda bulunmaları kaçınılmaz olmuştur. Marka değerini yükseltmek, daha güçlü hale getirmek isteyen markalar, hedef kitleleri ile sürekli bir etkileşim içinde olmak durumundadırlar. Hedef pazarlarındaki tüketicilerin kişilik özelliklerini de belirleyebildikleri ölçüde kişiselleştirilmiş sunumlarla daha başarılı olabilme imkanına kavuşmuşlardır. Bu çalışma kapsamında gerçekleştirilen araştırma bulgularına göre sosyal medya pazarlama uygulamaları marka değerini ve bileşenlerini, marka değeri de tüketici satın alma niyetini olumlu yönde etkilemektedir. Kişilik özelliklerindeki farklılıklar her iki etkide farklılıklara neden olmaktadır.
EFL Classes Must Go Online! Teaching Activities and Challenges during COVID-19 Pandemic in Indonesia
Authors: Atmojo Arief Eko Priyo , Nugroho Arif 
Published: May 2020

In view of the COVID-19 pandemic and government policy to carry out online learning, the present research is aimed at investigating how EFL teachers carry out online EFL learning and its challenges. 16 EFL teachers volunteered to participate in this research through invitation. The EFL teachers were requested to make written reflections regarding their practices in carrying out online EFL learning and the challenges they encounter. Five of them were involved in a follow-up interview individually. Semi-structured interview was administered. Data coding was done and appropriate extracts were informed in results section. To validate the data, data coding was done independently by both researchers, continued by several cycles of discussion. As results, the EFL teachers have carried out online learning through a series of activities ranging from checking the students’ attendance to giving score on the students’ works synchronously or asynchronously depending on each school policy. Various applications and platforms ranging from learning management system to additional resource are employed. However, many problems emerge from the students, the teachers, and the students’ parents along with the valid reasons. Therefore, the online learning does not run well since it lacks of preparation and planning. Implications for better online learning are discussed. Future prospective researches are directed and encouraged. Keywords: COVID-19, EFL teachers, online EFL learning, technology enhanced language learning, technology in language learning.
Efficacy of P2/MS and AFP in Early Prediction of Hepatocellular Carcinoma Recurrence
Authors: TOPAL Firdevs , TAŞDEMİR Ünal , GÜMÜŞ Zeynep Zehra , GÜNAY Süleyman , ÇAMYAR Hakan , AKBULUT Sabiye , SARITAŞ YÜKSEL Elif , VATANSEVER Sezgin , TOPAL Fatih Esat 
Published: May 2020

Amaç: P2/MS basit, ucuz ve not-invaziv bir test olup sirozda karaciğer fibrozunu değerlendirmek için kullanılır. Hepatoselüler karsinomada artmış alfa-fetoprotein düzeyleri rekürrens ile ilişkilidir. Bu çalışmada hepatoselüler karsinoma nüksünün erken dönem öngörümünde P2/MS ve alfa-fetoproteinin etkinliği ve P2/MS ve alfa-fetoprotein için sınır değerler belirlenmesi amaçlanmıştır.Gereç ve yöntem: Retrospektif olarak 69 hepatoselüler karsinoma hastası, rekürrens varlığı açısından tarandı. Kanser rekürrensi radyolojik olarak trifazik tomografi ve manyetik rezonans inceleme ile belirlendi. P2/MS formülü için [trombosit sayısı (109/L)]2/[monosit yüzdesi x nötrofil yüzdesi] kullanıldı.Bulgular: Toplam 42 hastanın hepatoselüler karsinoma rekürrensi vardı. Rekürrens öngörümü için P2/MS sınır değeri ≤59,9 alındığında %100 özgüllük ve %95,24 duyarlılık saptandı. Alfa-fetoprotein için sınır değeri &gt;57,5 alındığında ise %83,3 özgüllük ve %92,6 duyarlılık saptandı.Sonuç: Bu bulgular ışığında, P2/MS ve alfa-fetoprotein hepatoselüler karsinoma rekürrensini öngördürmede güvenilir belirteçler olarak kabul edilebilir. Hepatoselüler karsinoma rekürrensinin erken tahmininde non-invaziv test olarak kullanılabileceklerini öneriyoruz. Anahtar kelimeler: P2/MS, AFP, hepatoselüler kanser, rekürrens.Efficacy of P2/MS and AFP in Early Prediction of Hepatocellular Carcinoma RecurrenceAbstract: Objective: P2/MS is a simple, inexpensive and non-invasive test for the evaluation of hepatic fibrosis in cirrhosis. Elevated alpha-fetoprotein levels in hepatocellular carcinoma is related with recurrence. We aimed to examine the efficacy of P2/MS and alpha-fetoprotein in early prediction of hepatocellular carcinoma recurrence and to determine a cut-off value for P2/MS and alpha-fetoprotein. Methods: Sixty nine patients with hepatocellular carcinoma were retrospectively scanned for recurrence existence. The recurrence of hepatocellular carcinoma was diagnosed radiologically, via 3-phase tomography and magnetic resonance investigation. The formula of P2/MS was platelet count (109/L)2/[monocyte count (%) x neutrophil count (%)]. Results: Forty two patients had hepatocellular carcinoma recurrence. For the recurrence prediction, the cut-off value of P2/MS was ≤59.9 with 100% specificity and 95.24% sensitivity. The cut-off value of alpha-fetoprotein was found &gt;57.5 with 83.3% sensitivity and 92.6% specificity. Conclusion: With these findings, P2/MS and alpha-fetoprotein seems as reliable markers for the prediction of hepatocellular carcinoma recurrence. We suggest that they can be used as non-invasive tools for the early estimation of hepatocellular carcinoma recurrence. Key Words: P2/MS, AFP, hepatocellular carcinoma, recurrence.
Resúmenes de literatura mundial
Authors: Acuña Juan Manuel , López Alfonso 
Published: May 2020

El efecto de los antiobióticos profilacticos en la morbilidad, Alfonso López y Juan Manuel Acuña A. Prueba de no stress falsamente reactiva en embarazos post-términoPrueba de ocitocina y retardo de crecimiento intra uterinoPrematurez iatrogénica debida a terminación electiva de embarazos no complicadosEfectos sobre el neonato del sulfato de magnesia administrado a la madreEfectos de la reducción de peso corporal sobre los andrógenos plasmáticos en la mujer infértil obesa
Revisión de temas. Tratamiento del Shock Séptico sin Drogas Vasopresoras
Authors: Zuñiga C. Jorge E. 
Published: May 2020

El shock séptico especia lmente debido a micro-organismos gram negativos, como consecuencia de la enfermedad inflamatoria pelvica aguda post-aborto provocado, es muy común en nuestro medio y representa una morbilidad y mortalidad bastante elevadas. Se presenta un análisis de 15 casos tratados sin drogas de efecto vasopresor y más bien se tiene en cuenta el mecanismo fisiopatológico de una falta de perfusión tisular, para ejercer esfuerzos en un adecuado remplazo de líquidos, utilizando soluciones electrolíticas concomitantemente con drogas de acción vasodilatadora, para vencer el vaso-espasmo y mejorar la perfusión de todos los tejidos comprometidos.
Las espátulas obstétricas materno fetal y morbilidad
Authors: Ortíz Herrera Eduardo , Thompson James P. 
Published: May 2020

Con la intención de analizar comparativamente el uso de las espátulas y el del fórceps y las posibles lesiones que se presentan en la madre y el recién nacido, se planeó un trabajo prospectivo en el hospital de alto riesgo materno infantil de Saint Joseph's de Paterson, afiliado a la Universidad de New Jersey.Se analizaron 51 casos de aplicación de espátulas y 55 casos de aplicación de fórceps en ¡guales condiciones.En ninguno de los grupos se encontraron lesiones graves de la madre o del niño.Se apreció una menor incidencia de lesiones moderadas del recién nacido en los casos de aplicación de espátulas. No se apreció ninguna lesión en los casos del grupo de las espátulas en un 92,15% de las pacientes, en contraste con un 29.00% de lesiones leves y moderadas de las pacientes del grupo de los fórceps. x2 = 43,6, p = < 0.0001.
PENGENDALIAN INTERNAL SEBAGAI VARIABEL MODERASI PADA PENGARUH ANTARA DESENTRALISASI TERHADAP KINERJA MANAJERIAL
Authors: Hidayati Nanik , Dianawati Wiwiek 
Published: May 2020

Dalam rangka pelaksanaan Anggaran Pendapatan dan Belanja Negara (APBN), maka diterbitkanlah Peraturan Menteri Keuangan (PMK) No. 190/PMK.05/2012 tentang tatacara pembayaran dalam rangka pelaksanaan APBN, yang memberi kewenangan dan keleluasan secara nyata dan bertanggungjawab kepada setiap satuan kerja untuk mengelola keuangan Negara. Untuk meningkatkan kinerja maka salah satu upaya yang dilakukan adalah memperkuat sistem pengendalian internal. Penelitian ini bertujuan untuk mengetahui apakah tingkat desentralisasi berpengaruh terhadap kinerja manajerial BPS se Jawa Timur serta untuk mengetahui apakah pengendalian internal memperkuat pengaruh tingkat desentralisasi terhadap kinerja manajerial BPS se Jawa Timur. Penelitian dilakukan terhadap tingkat desentralisasi, pengendalian internal dan kinerja manajerial Pejabat Pembuat Komitmen di Badan Pusat Statistik se Jawa Timur. Hasil penelitian menyatakan bahwa desentralisasi tidak berpengaruh terhadap kinerja manajerial meskipun arahnya sudah sesuai dengan yang diprediksikan. Selain itu pengendalian internal juga tidak memperkuat pengaruh desentralisasi terhadap kinerja manajerial meskipun arahnya sudah sesuai dengan yang diprediksikan. Keyword: desetralisasi, pengendalian internal dan kinerja manajerial