bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intensification of the dispersion of the global climatic landscape and its potential as a new climate change indicator
Authors: Guan Yanlong , Lu Hongwei , He Li , Adhikari Hari , Pellikka Petri , Maeda Eduardo , Heiskanen Janne 
Published: July 2020

Abstract
Increases and decreases in the areas of climatic types have become one of the most important responses to climate warming. However, few attempts have been made to quantify the complementary relationship between different climate types or to further assess changes in the spatial morphology. In this study, we used different observed datasets to reveal a dispersion phenomenon between major global climate types in 1950–2010, which is significantly consistent with the increasing trend of global temperatures. As the standard deviation of the area of major climate zones strengthened in 1950–2010, the global climatic landscape underwent notable changes. Not only did the area change, but the shape of the overall boundary became regular, the aggregation of climatic patches strengthened, and the climatic diversity declined substantially. However, changes in the global climatic landscapes are not at equilibrium with those on the continental scale. Interpreting these climatic morphological indices can deepen our understanding of the redistribution response mechanisms of species to climate change and help predict how they will be impacted by long-term future climate change.
Identification method of early water influx in gas reservoirs
Authors: Zheng Yuping 
Published: July 2020

Abstract
The formation water will directly lead to the loss of gas well productivity and the reduction of gas reservoir recovery, and will also have a serious adverse impact on the development of gas reservoirs. In the development of water flooding gas reservoirs, early identification of water invasion is a prerequisite for making full use of the dry period for production and actively implementing water treatment measures. At present, the identification methods of water invasion mainly include production water analysis, pressure drop curve identification, well test monitoring and simulation calculation. Based on the principles, adaptability, and existing problems of these methods, water intrusion identification should be carried out based on gas well geological information using multiple methods.
Evaluation of CO2 storage potential of oil reservoirs in Ordos Basin
Authors: Zhou Yuli , Chen Jianguo , Liu Jinhui , Yuan Hongyong 
Published: July 2020

Abstract
The huge impact of the emission of the greenhouse gas CO2 on the global climate and environment has caused wide concern all over the world. Deep CO2 emission reduction is the only way for sustainable development of human beings. In order to meet the urgent need of sustainable economic and social development, effective measures must be taken to achieve large-scale CO2 emission reduction. As an increasingly mature and feasible technology, CO2 geological sequestration has become one of the effective ways to achieve large-scale CO2 emission reduction. In ordos basin as the research object, this paper documents and basic information system collect and organize data, evaluated the ordos basin in turn CO2 enhanced oil recovery (CO2-EOR) and CO2 sequestration potential, depleted oil reservoir and select 60 oilfield in ordos basin CO2 sequestration potential analysis and to meet the requirements of 27 oilfield seal ratio analysis, the results showed that: Under the screening condition that the burial depth is greater than 800 m, when assuming that 60 oilfields in the ordos basin are all used for co2-eor, the CO2 sequestration potential of the reservoir is about 318.27 Mt; when 60 oilfields are all treated as abandoned reservoirs, the CO2 sequestration potential of the reservoir is about 1221.57 Mt. When the amount of CO2 to be sequestered is small, Huachi (Changqing) field should be preferred, and when the amount of CO2 to be sequestered is large, Jiyuan (Changqing) field should be preferred. In this paper, the evaluation results of CO2 sequestration potential of reservoir in ordos basin are of great significance to the further development of theoretical sequestration potential evaluation and engineering planning of ordos basin.
Understanding effects of printhead geometry in aerosol jet printing
Authors: Tafoya Rebecca R , Secor Ethan B 
Published: July 2020

Abstract
Aerosol jet printing offers a versatile, high-resolution digital patterning capability broadly relevant to flexible and printed electronic systems. Despite its promise and numerous demonstrations, the theoretical principles driving process outputs have not been thoroughly explored. Here a custom-built, modular printing system is developed to provide a head-to-head comparison of two print nozzle geometries to better understand the technology. Print resolution data from a range of process parameters are analyzed using a support vector machine framework. The linear deposition rate is identified as a key variable, which can confound careful studies of printing performance. Taking this into account, a clear difference is observed between the printheads, corresponding to a difference in resolution of 57% ± 11% under typical conditions. Models to understand differences in aerodynamic and mass transport effects identify enhanced drying within a large diameter printhead as a likely cause of this difference. Overall, this study provides improved understanding of the aerosol jet printing process, including valuable insight to inform process optimization, robust data analysis, ink formulation, and printer geometric design.
Interactions of different hydrocolloids with milk proteins
Authors: Hege Judith , Palberg Thomas , Vilgis Thomas A 
Published: July 2020

Abstract
To control rheological properties and accomplish perfect sensory properties and mouthfeel, polysaccharides are added to milk-based beverages. However, in contrast to expectations, it is often found that adding low concentrations of xanthan gum or guar gum to milk provokes phase separations of unclear physical origin. From this observation, questions arise regarding the interaction of added polysaccharides and the proteins present in milk – caseins and whey proteins. The focus of this study is to investigate such systems and to understand the basic interactions of caseins and whey proteins with different hydrocolloids. The hydrocolloids used in this study are xanthan gum, guar gum, gellan gum as well as iota-carrageenan, which were dissolved in pasteurized, non-homogenized, skimmed milk. The methods used for the examinations are light microscopy, measurement of zeta potential, atomic force microscopy and measurement of particle sizes. It was found for the case of xanthan gum dissolved in milk that the xanthan gum molecules and some of the whey proteins are found in the upper phase whereas the casein micelles as well as whey proteins are in the lower phase. For the case of guar gum dissolved in milk, the guar gum molecules are present in the upper phase and the casein micelles are present in the lower phase. This phase separation is probably caused by depletion interaction. Whey proteins are found in both phases. For the cases of iota-carrageenan, respectively, gellan gum dissolved in milk no macroscopic phase separation is observed and the measurements suggest the formation of complexes between the hydrocolloid and whey proteins.
Revisiting the coupling between accessibility and population growth
Authors: Volpati Valerio , Barthelemy Marc 
Published: July 2020

Abstract
The coupling between population growth and transport accessibility has been an elusive problem for more than 60 years now. Due to the lack of theoretical foundations, most of the studies that considered how the evolution of transportation networks impacts the population growth are based on regression analysis in order to identify relevant variables. The recent availability of large amounts of data allows us to envision the construction of new approaches for understanding this coupling between transport and population growth. Here, we use a detailed dataset for about 36 000 municipalities in France from 1968 until now. In the case of large urban areas such as Paris, we show that growth rate statistical variations decay in time and display a trend towards homogenization where local aspects are less relevant. We also show that growth rate differences due to accessibility are very small and can mostly be observed for cities that experienced very large accessibility variations. This suggests that the relevant variable for explaining growth rate variations is not the accessibility but its temporal variation. We propose a model that integrates the stochastic internal variation of the municipalities population and an inter-urban migration term that we show to be proportional to the accessibility variation and has a limited time duration. This model provides a simple theoretical framework that allows to go beyond econometric studies and sheds a new light on the impact of transportation modes on city growth.
A powerful framework for an integrative study with heterogeneous omics data: from univariate statistics to multi-block analysis
Authors: Duruflé Harold , Selmani Merwann , Ranocha Philippe , Jamet Elisabeth , Dunand Christophe , Déjean Sébastien 
Published: July 2020

AbstractHigh-throughput data generated by new biotechnologies require specific and adapted statistical treatment in order to be efficiently used in biological studies. In this article, we propose a powerful framework to manage and analyse multi-omics heterogeneous data to carry out an integrative analysis. We have illustrated this using the mixOmics package for R software as it specifically addresses data integration issues. Our work also aims at applying the most recent functionalities of mixOmics to real datasets. Although multi-block integrative methodologies exist, we hope to encourage a more widespread use of such approaches in an operational framework by biologists. We have used natural populations of the model plant Arabidopsis thaliana in this work, but the framework proposed is not limited to this plant and can be deployed whatever the organisms of interest and the biological question may be. Four omics datasets (phenomics, metabolomics, cell wall proteomics and transcriptomics) were collected, analysed and integrated to study the cell wall plasticity of plants exposed to sub-optimal temperature growth conditions. The methodologies presented here start from basic univariate statistics leading to multi-block integration analysis. We have also highlighted the fact that each method, either unsupervised or supervised, is associated with one biological issue. Using this powerful framework enabled us to arrive at novel conclusions on the biological system, which would not have been possible using standard statistical approaches.
Seqminer2: an efficient tool to query and retrieve genotypes for statistical genetics analyses from biobank scale sequence dataset
Authors: Yang Lina , Jiang Shuang , Jiang Bibo , Liu Dajiang J , Zhan Xiaowei 
Published: July 2020

Abstract

Summary
Here, we present a highly efficient R-package seqminer2 for querying and retrieving sequence variants from biobank scale datasets of millions of individuals and hundreds of millions of genetic variants. Seqminer2 implements a novel variant-based index for querying VCF/BCF files. It improves the speed of query and retrieval by several magnitudes compared to the state-of-the-art tools based upon tabix. It also reimplements support for BGEN and PLINK format, which improves speed over alternative implementations. The improved efficiency and comprehensive support for popular file formats will facilitate method development, software prototyping and data analysis of biobank scale sequence datasets in R.

Availability and implementation
The seqminer2 R package is available from https://github.com/zhanxw/seqminer. Scripts used for the benchmarks are available in https://github.com/yang-lina/seqminer/blob/master/seqminer2%20benchmark%20script.txt.

Supplementary information
Supplementary data are available at Bioinformatics online.
The finer points of urban adaptation: intraspecific variation in lizard claw morphology
Authors: Falvey Cleo H , Aviles-Rodriguez Kevin J , Hagey Travis J , Winchell Kristin M 
Published: July 2020

AbstractHuman activity drastically transforms landscapes, generating novel habitats to which species must adaptively respond. Consequently, urbanization is increasingly recognized as a driver of phenotypic change. The structural environment of urban habitats presents a replicated natural experiment to examine trait–environment relationships and phenotypic variation related to locomotion. We use geometric morphometrics to examine claw morphology of five species of Anolis lizards in urban and forest habitats. We find that urban lizards undergo a shift in claw shape in the same direction but varying magnitude across species. Urban claws are overall taller, less curved, less pointed and shorter in length than those of forest lizards. These differences may enable more effective attachment or reduce interference with toepad function on smooth anthropogenic substrates. We also find an increase in shape disparity, a measurement of variation, in urban populations, suggesting relaxed selection or niche expansion rather than directional selection. This study expands our understanding of the relatively understudied trait of claw morphology and adds to a growing number of studies demonstrating phenotypic changes in urban lizards. The consistency in the direction of the shape changes we observed supports the intriguing possibility that urban environments may lead to predictable convergent adaptive change.
Back from the Ashes of Communism: The Rebirth of the Social Work Profession in Romania
Authors: Lazăr Florin , Lightfoot Elizabeth , Iovu Mihai Bogdan , Dégi László Csaba 
Published: July 2020

Abstract
The profession of social work in Romania was re-established in the early 1990s after being completely abolished for three decades during the communist period. This article reports findings from the first national survey of Romanian social workers, which studied characteristics of social workers and their roles, tasks and types of services provided. In addition, it explores how burnout, income and efficacy were associated with social workers’ plans for leaving the profession or country. This study used a seventy-three-item online survey tool to collect data from 1,057 social workers from across Romania using a quota sampling strategy. Romanian social workers skewed young, female and from the Romanian ethnic group. Whilst Romania has a large rural population, social workers primarily practiced in urban areas. Social workers had fairly high levels of job satisfaction and feelings of self-efficacy, and were most likely to be working in child and family protection using direct practice methods. Over one-fifth of social workers indicated they were considering leaving the field in the next two years. Those with higher incomes had lower odds that they planned to leave the field within two years, whilst those with burnout had over twice the odds they planned to leave the field.
Comparative wood anatomy ofAstropanaxandNeocussonia, an Afro-Malagasy lineage of Araliaceae
Authors: Zhernova Daiana A , Nilova Maya V , Oskolski Alexei A 
Published: July 2020

AbstractAstropanax and Neocussonia are two recently resurrected genera of Araliaceae that had long been considered as an Afro-Malagasy lineage of Schefflera. The wood structure of 11 Neocussonia spp. and eight Astropanax spp. has been studied. Neocussonia shows a higher average length of vessel elements (1319 µm) and number of bars on perforation plates (up to 66) than any other Araliaceae examined to date. Neocussonia is distinct from Astropanax by its smaller diameter and higher frequency of vessels, rare occurrence of simple perforation plates, more numerous bars on scalariform perforation plates and smaller intervessel pits. The interspecific variation in percentage of simple perforation plates, bar number on scalariform perforation plates, vessel frequency and uniseriate ray number is affected by seasonality in temperature and precipitation. The sharp distinction in wood structure between samples of A. abyssinicus from Cameroon and Burundi suggests that the populations from different parts of the disjunct range represent two different species. Our data also suggest that A. goetzenii is an artificial group. Astropanax myrianthus from Madagascar and A. polysciadus from continental Africa, two cryptic species that have long been included in Schefflera myriantha, show significant differences in vessel size and grouping, percentage of simple perforation plates and intervessel pit size.
The glycocalyx core protein Glypican 1 protects vessel wall endothelial cells from stiffness-mediated dysfunction and disease
Authors: Mahmoud Marwa , Mayer Mariya , Cancel Limary M , Bartosch Anne Marie , Mathews Rick , Tarbell John M 
Published: July 2020

AbstractAimsArterial stiffness is an underlying risk factor and a hallmark of cardiovascular diseases. The endothelial cell (EC) glycocalyx is a glycan rich surface layer that plays a key role in protecting against EC dysfunction and vascular disease. However, the mechanisms by which arterial stiffness promotes EC dysfunction and vascular disease are not fully understood, and whether the mechanism involves the protective endothelial glycocalyx is yet to be determined. We hypothesized that endothelial glycocalyx protects the endothelial cells lining the vascular wall from dysfunction and disease in response to arterial stiffness.Methods and resultsCells cultured on polyacrylamide (PA) gels of substrate stiffness 10 kPa (mimicking the subendothelial stiffness of aged, unhealthy arteries) showed a significant inhibition of glycocalyx expression compared to cells cultured on softer PA gels (2.5 kPa, mimicking the subendothelial stiffness of young, healthy arteries). Specifically, gene and protein analyses revealed that a glycocalyx core protein Glypican 1 was inhibited in cells cultured on stiff PA gels. These cells had enhanced endothelial cell dysfunction as determined by enhanced cell inflammation (enhanced inflammatory gene expression, monocyte adhesion, and inhibited nitric oxide expression), proliferation, and EndMT. Removal of Glypican 1 using gene-specific silencing with siRNA or gene overexpression using a plasmid revealed that Glypican 1 is required to protect against stiffness-mediated endothelial cell dysfunction. Consistent with this, using a model of age-mediated stiffness, older mice exhibited a reduced expression of Glypican 1 and enhanced endothelial cell dysfunction compared to young mice. Glypican 1 gene deletion in knockout mice (GPC1−/−) exacerbated endothelial dysfunction in young mice, which normally had high endothelial expression, but not in old mice that normally expressed low levels. Endothelial cell dysfunction was exacerbated in young, but not aged, Glypican 1 knockout mice (GPC1−/−).ConclusionArterial stiffness promotes EC dysfunction and vascular disease at least partly through the suppression of the glycocalyx protein Glypican 1. Glypican 1 contributes to the protection against endothelial cell dysfunction and vascular disease in endothelial cells.
Spotted Lanternfly (Hemiptera: Fulgoridae) Can Complete Development and Reproduce Without Access to the Preferred Host, Ailanthus altissima
Authors: Uyi Osariyekemwen , Keller Joseph A , Johnson Anne , Long David , Walsh Brian , Hoover Kelli 
Published: July 2020

Abstract
Despite its broad host range, the spotted lanternfly Lycorma delicatula (White), is known to have a marked preference for Ailanthus altissima. However, whether this polyphagous phloem feeder can complete its life cycle in the absence of A. altissima is unknown. We examined the performance of L. delicatula with and without access to A. altissima by tracking development, survival, host tree species association, and oviposition in large enclosures planted with Salix babylonica and Acer saccharinum along with either A. altissima or Betula nigra. We monitored enclosures from late May 2019 through June 2020. Lycorma delicatula survival was slightly higher in enclosures with A. altissima and 50% of individuals in A. altissima enclosures reached the adult stage ~6.5 d earlier than in enclosures without A. altissima. In the presence of A. altissima, nymphs were most frequently observed on this host while adults were found at similar frequencies on A. altissima and A. saccharinum. In the absence of A. altissima, nymphs were most frequently associated with S. babylonica and A. saccharinum, while adults were most often found on A. saccharinum. Females laid a total of 46 and 6 egg masses in enclosures with and without A. altissima, respectively, before freezing temperatures killed the remaining adults. The proportion of eggs that hatched per egg mass did not differ between treatments. Although L. delicatula can complete development and reproduce on other host species without access to A. altissima, fitness was reduced. These findings have implications for management that relies exclusively on treatment of A. altissima.
SARS, MERS and COVID-19: clinical manifestations and organ-system complications: a mini review
Authors: Gerges Harb Jad , Noureldine Hussein A , Chedid Georges , Eldine Mariam Nour , Abdallah Dany Abou , Chedid Nancy Falco , Nour-Eldine Wared 
Published: July 2020

ABSTRACT
Middle East Respiratory Syndrome (MERS), Severe Acute Respiratory Syndrome (SARS) and Coronavirus Disease 2019 (COVID-19) are caused by three distinct coronaviruses belonging to the same genus. COVID-19 and its two predecessors share many important features in their clinical presentations, and in their propensity for progression to severe disease which is marked by high rates of morbidity and mortality. However, comparison of the three viral illnesses also reveals a number of specific differences in clinical manifestations and complications, which suggest variability in the disease process. This narrative review delineates the pulmonary, cardiac, renal, gastrointestinal, hepatic, neurological and hematologic complications associated with these three respiratory coronaviruses. It further describes the mechanisms of immune hyperactivation—particularly cytokine release syndrome—implicated in the multi-organ system injury seen in severe cases of MERS, SARS and COVID-19.