bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic Value of Urine sTREM-1 and Urine C-reactive Protein for Infants with Late Onset Neonatal Sepsis
Authors: Ozdemir Senem Alkan , Colak Ruya , Ergon Ezgi Yangin , Calkavur Sebnem 
Published: November 2019

Abstract
Objective Noninvasive markers have been increasingly used as a diagnostic marker for sepsis detection and monitoring of the disease. The aim of this observational, prospective pilot study was to investigate the diagnostic performance of urinary soluble triggering receptor expressed on myeloid cells (sTREM-1) and urine C-reactive protein (CRP) levels in the late onset neonatal sepsis and to compare them with serum CRP levels.
Materials and Methods Sixty-six infants with clinical sepsis were included. Urine sTREM-1 and urine CRP were collected at the diagnosis of late-onset sepsis. All laboratory investigations were also noted from the infants.
Results There were no significant differences between characteristics of the infants. Culture-positive neonates had significantly higher urine sTREM-1 than culture-negative neonates (p < 0.001). Using a cut-off point for urine sTREM-1 of 129 pg/mL, the sensitivity was 0.63, the specificity was 0.84, positive predictive value was 0.80, negative predictive value was 0.70. Urine sTREM-1 and urine CRP were recollected on the seventh day of sepsis treatment and it was found that the levels of sTREM-1 and CRP decreased.
Conclusion This is the first study in the literature which evaluates the place of urine sTREM-1 and urine CRP in the diagnosis of neonatal sepsis. Urine sTREM-1 and urine CRP may be useful in the diagnosis of sepsis and in evaluating the effect of antibiotic treatment.
Purity and yield of melanoma exosomes are dependent on isolation method
Authors: La Shu Shin , Yang Yunchen , Allen Cheryl L. , Hurley Edward , Tung Kaity H. , Minderman Hans , Wu Yun , Ernstoff Marc S. 
Published: November 2019

ABSTRACTBoth exosomes and soluble factors have been implicated in the generation of an immunosuppressive tumour microenvironment. Determining the contribution of each requires stringent control of purity of the isolated analytes. The present study compares several conventional exosome isolation methods for the presence of co‐enriched soluble factors while isolating exosomes from human melanoma‐derived cell lines. The resultant preparations were analysed by multiplex bead array analysis for cytokine profiles, and by electron microscopy and nanotracking analysis for exosome size distribution and concentration. It is demonstrated that the amount and repertoire of soluble factors in exosome preparations is dependent upon the isolation method used. A combination of ultrafiltration and size exclusion chromatography yielded up to 58‐fold more exosomes than ultracentrifugation, up to 836‐fold lower concentrations of co‐purified soluble factors when adjusted for exosome yield, and a greater than two‐fold increase in PD‐L1 expressing exosomes. Mechanistically, in context of the immunomodulatory effects of exosomes, the exosome isolation method should be carefully considered in order to limit any effects due instead to co‐eluted soluble factors.
A Study on the Correlation Between Poles and Cuts in ππ Scattering*
Authors: Dai Ling-Yun , Kang Xian-Wei , Luo Tao , Meißner Ulf-G. 
Published: November 2019

Abstract
In this paper we propose a dispersive method to describe two-body scattering with unitarity imposed. This approach is applied to elastic ππ scattering. The amplitudes keep single-channel unitarity and describe the experimental data well, and the low-energy amplitudes are consistent with that of chiral perturbation theory. The pole locations of the σ, f
0(980), ρ(770) and f
2(1270) and their couplings to ππ are obtained. A virtual state appearing in the isospin-two S-wave is confirmed. The correlations between the left (and right) hand cut and the poles are discussed. Our results show that the poles are more sensitive to the right hand cut rather than the left hand cut. The proposed method could be used to study other two-body scattering processes.
Stability of Macroscopic Binary Systems*
Authors: Adamian G. G. , Antonenko N. V. , Lenske H. , Sargsyan V. V. 
Published: November 2019

Abstract

The Darwin instability effect in the binary systems (di-planets, di-stars, and di-galaxies) is analyzed within the model based on the Regge-like laws. All possible binary stars are found satisfying the Darwin instability condition that requires to search for other mechanism triggering the merger of the contact binary objects. New analytical formulas are obtained for the orbital rotation period and the relative distance between components of the binary system. The decreasing and increasing periods as functions of mass asymmetry are related, respectively, with the non-overlapping and overlapping stage of the binary object evolution.
Similar Early Growth of Out-of-time-ordered Correlators in Quantum Chaotic and Integrable Ising Chains*
Authors: Yan Hua , Wang Jiao-Zi , Wang Wen-Ge 
Published: November 2019

Abstract

Previous studies show that, in quantum chaotic and integrable systems, the so-called out-of-time-ordered correlator (OTOC) generically behaves differently at long times, while, it may show similar early growth in one-body systems. In this paper, by means of numerical simulations, it is shown that OTOC has similar early growth in two quantum many-body systems, one integrable and one chaotic.
An Improved Collaborative Filtering Algorithms Based on Maximum Entropy Model and Markov Process to Mine User Behavior
Authors: Huang Guanghua , Yin Feng , Feng Jiulin 
Published: November 2019

Abstract
Aiming at problems of data sparsity and poor interpretability of recommendation reasons in user-based collaborative filtering algorithm, an improved collaborative filtering algorithm based on maximum entropy model and markov process is proposed to mine user behavior habits. Firstly, the maximum entropy model is established through the user-behavior matrix of collaborative filtering algorithm, and the user behavior is fuzzily and preliminarily mined. Secondly, fuzzy behavior information obtained by the maximum entropy model is introduced as the initial state of markov process, and an optimization model is set up according to the internal relation of user-behavior matrix, thus reaching the state probability transition matrix. Once the markov process reaches a stable state, the user’s final behavior habit is excavated. Finally, this user behavior is integrated into the recommendation process, so that the interpretability of the recommendation is enhanced. The experimental results show that the improved collaborative filtering algorithm can promote the recommendation accuracy.
An Evaluation Model for College Student ‘s Loan Repayment Ability based on NNN
Authors: Fan Yanghai , Cheng Ming , Yang Lijun 
Published: November 2019

Abstract
This paper designs a risk model suitable for student loans. It is proposed to use NNN algorithm assess the student loan repayment ability. By establishing an evaluation index system, the student’s relevant indicator data is compared with the evaluation index standard, and the closeness value of the evaluation index is calculated, and finally the evaluation conclusion is obtained. It provides a reference for the final establishment and improvement of the student loan system in China.
Prediction-based Resource Provision and Virtual Machines Placement in Cloud Data Center
Authors: Du Shengyu , Wu Yufei , Yin Changqing 
Published: November 2019

Abstract
With the rapid development of virtualization, cloud servers provide the power and flexibility that single servers struggle to provide. However, low utilization of physical machines and high energy consumption are the main concerns for cloud service providers. In this paper, we propose a predict-and-place framework to decrease the number of active physical machines in cloud centers. We analyze the historical VM (virtual machine) request records to predict the VM demands in the next several days and then use an offline VM placement strategy to keep the number of active servers as less as possible while satisfying the SLA (Service-Level Agreement) requirements. In the prediction process, we enhanced the classical Holt’s linear prediction method on account of inevitable outliers to increase the prediction accuracy. We conduct experiments to compare the prediction accuracy of Perceptron, classical Holt-Winters, and our refined, robust Holt-Winters method. The experiment based on real data shows the simple perceptron has an inferior result. Our improved prediction method reduces the MAPE (Mean Absolute Percentage Error) by about 50% compared with the classical one, and the predict-and-place framework decreases the average number of active physical machines effectively in the cloud data center.
Research on SDN Flow Secure Access Control
Authors: Yang Hu , JiaXing Lei 
Published: November 2019

Abstract
In order to ensure the Software Defined Network (SDN) flow security access, this paper puts forward a SDN terminal access control system through the deep study on the terminal security access solution in the existing SDN. This system combines the traditional terminal access control technology with the new SDN network and mainly implements some functions such as user’s identity authentication, terminal security status assessment, user’s service authorization, QoS control, and so on. Simultaneously, the system security is analyzed in detail. The network simulation in Mininet is carried out in combination with the RYU controller secondary developed so as to complete the experiment of access control function and communication delay performance. The results show that the security access control system of SDN flow has flexible access control security strategies and then can detect the threats from the insecure terminal access in SDN. This can not only realize the identity authentication of users but also ensure the security of access terminal, and thus realizing the access authorization of terminals in different safe states.
A Hybrid Feature Selection Method for Network Traffic Anomaly Detection
Authors: Wu Haoming , Zhang Bin , Dong Shuqin 
Published: November 2019

Abstract
In order to keep fast and accurate in feature selection for network traffic anomaly detection, this paper proposes a hybrid feature selection method. Firstly, to reduce the calculation and to identify the redundant features, we regard the ratio of mutual information between features to a feature entropy as the redundancy degree of the feature. If the ratio is greater than a predefined threshold, the feature is judged as redundant and will be deleted from the feature set. Secondly, based on the feature set whose redundant features have been removed, this method uses the ratio of the anomaly detection accuracy after and before delete one feature from the feature set to measure the effect of the feature on detection. Then, the features are sorted in ascending order of the ratio and the top k features with the highest detection accuracy are selected as the result. Experimental results show that the proposed method can quickly screen out a feature subset with good detection performance and lower dimensions.
Determination of the electrostatic potential produced by a uniformly charged ring
Authors: Mesa Fernando , Orrego Edwin , Villa Guillermo 
Published: November 2019

Abstract
Finding the electrostatic potential produced by a point load is an easy task, when that point load is replaced by a load distribution this task is complicated, the difficulty of this procedure depends on the place where you want to know the potential, it is not the same to find the potential at a given point to find it in any place in space. In this case we will work with a uniformly charged two-dimensional ring, the problem that arises is the obtaining of the electrostatic potential at any point around the ring, for this we will look for the conditions that must be met to pose the problem, a theoretical solution for this problem, in which we find the Legendre polynomials and finally proceeds to make this same solution using the two dimensional finite element method.
Optimal control with bounded entries principle of Pontryagin
Authors: Mesa F , Orrego E , Ramirez C 
Published: November 2019

Abstract
The generally, systems control the saturation results in their dynamics, either in their control signal, in their states or in both. This paper presents the theory and wording of the Pontryagin principle, which has been applied as this type of continuous time problems, to obtain control laws that optimize the index in question. Likewise, a problem is presented and solved with which the application of the Pontryagin principle is exposed and finally the conclusions are presented.
Performance in saline environment of a carbon steel surface modified by three-dimensional ion implantation
Authors: Sanabria F , Viejo F , V-Niño E D 
Published: November 2019

Abstract
The three-dimensional ion implantation method is presented as a new plasma-ion technology for advanced surface treatment. It is based on a high voltage pulsed discharge activated in the low-pressure range and applicable to solid surface immersed in a gaseous atmosphere. This process is carried out in the joint universal plasma and ion technologies experimental reactor and is widely used to improve the tribological properties and corrosion resistance of metallic materials, specially steels. In this study, the performance in a corrosive environment of a carbon steel surface-modified was evaluated. High-energy nitrogen ions were implanted on the surface of the material at different discharge voltages and times. Treated and non-treated substrates were exposed to saline solution for 35 days, where the effect of the surface modification was shown to decrease the corrosion rate and degradation of the implanted material surface compared to untreated substrates. The estimation of the nitrogen concentration from experimental parameters were calculated by a novel web application. Additionally, the effect of the implantation process of the modified steel structure was analyzed by optical emission spectroscopy, whose results detected mainly an increase of the nitrogen concentration at the surface of the modified substrates.
Russia - CERN cooperation: current status and perspectives
Authors: Smirnov Sergei 
Published: November 2019

Abstract
The paper presents the current status and future perspectives of international cooperation of Russia with the European Organization for Nuclear Research (CERN) in the fields of elementary particle, high enegry, and nuclear physics. It briefly describes the history of the Oranization, the development of the USSR and later Russian Federation scientific contacts with CERN and their legal basis, the present state of Russian scientific community involvement in CERN research programmes, as well as the future joint projects. The cooperation in education and training activities is also discussed.
Professional Qualifications’ Recognition and Megascience Projects
Authors: Zaplatina T S 
Published: November 2019

Abstract
The article is devoted to the analyzes of the issues of legal regulation of mutual recognition of professional qualifications in the context of increasing cross-border scientific cooperation, the emergence of new forms of cooperation and exchange of workforce, in particular in the framework of megascience class projects i.e. great science. The EU was the first integrational organization among the other organizations existing in Europe and the world that recognized the need to develop special legal mechanisms to ensure cross-border mobility of qualified specialists, and also adopted acts to conduct research within megascience (both at the EU and individual states level). The participation of scientists from various countries in megascience projects involves the integration of states not only to create structural units (cross-border associations) for the implementation of large-scale research, but also the integration of the economic and educational space, free movement of scientists.
Peculiarities of Integration of Russian Scientists into the World Scientific Medium
Authors: Ogorodnikov A Yu 
Published: November 2019

Abstract
The article describes the Russian experience in science institutionalization in the conditions of intensive innovative international interactions in the framework of the large-scaled research projects, such as megascience, etc. The research methodology of the science subject as the intellectual innovative potential carrier is discussed. The analysis of the results of the sociological research of the strategies for achieving goals by scientific field agents is described. The comparison of motivations and nature of professional self-fulfillment of two groups of scientists oriented towards the active international interaction and striving for attaining scientific objectives within one country is the distinctive feature of the article. The results of the research demonstrated institutional nonconformity of functioning of scientific systems on the level of separate scientists, organization and government regulation which restricts the opportunities for creating the positive image of the Russian science, protection against the risks of loss of the intellectual property in the course of international cooperation. The authors made a conclusion about the necessity to establish coordination structures engaging the scientists themselves which are able to integrate the activities of organizations in the framework of large-scaled long-term state programs.
Relevance of Philippine policies for muslim-friendly ecotourism management in adapting the climate change challenges
Authors: Tagoranao M , Gamon A 
Published: November 2019

Abstract
The impact of climate change on the natural environment has been a common case affecting the ecotourism management in Mindanao. There are many challenges and threats facing the ecotourism development, in particular, mitigating natural hazard and preserving a Muslim-friendly environment. The government needs policies for sustainable development, by improving an efficient use of natural resources and infrastructures for less greenhouse gas emissions (GHG), and provide permissible services and livelihood for poverty reduction to help the realizations of Millennium Development Goals (MDGs). Developing the Muslim-friendly ecotourism destinations, particularly in the Bangsamoro Autonomous Muslim Regions (BARMM) can overshadow the environmental risk and it will provide economic development and health protection to the local people and the tourists. The findings will show that aside from the Tourism Act 2009 and the climate Change Act (Republic Act 9729), the presence of well-formulated policies and guidelines on ecotourism in adapting the climate change will widen the possibilities for the people to further benefit from ecotourism development. In conclusion, it is of great importance that in facing the climate changes, the government must have strict environmental standards compounded by strict enforcement. However, for paradigm shift, it is necessary to be reminded that “we have to accept the evils of global development along with its blessings”.
Study on the medicinal plants against grouper iridovirus infection: A short communication
Authors: Xiao H , Yu Q , Wang T , Liu M , Qin X , Li S , Chen X , Wu S , Wang Y , Li P 
Published: November 2019

Abstract
As one serious viral pathogen in mariculture, grouper Iridovirus (GIV) could cause high mortality to cultured groupers, then effective treatments against GIV infection are needed. The effects of Thlaspi arvense Linn. extracts against GIV infection was assessed by different methods in this study. The safe concentration of the water extract of Thlaspi arvense Linn. was initially determined as ≤1.25 mg/mL, which showed no obvious cytotoxic effects on cell viability. Using the safe concentration, aptamer(Q2)-based based fluorescent detection assay and qRT-PCR results indicated that, Thlaspi arvense Linn. water extracts had excellent inhibitory effects against GIV infection in vitro and in vivo. In addition, the mechanism of Thlaspi arvense Linn. on the invasion process of the grouper iridovirus was examined, which showed that Thlaspi arvense Linn. water extracts had significant inhibitory effects at the stage of virus adsorption on the host cell membrane. The inhibitory rate was 87.48%. Overall, Thlaspi arvense Linn. water extracts have great antiviral effects, making it an interesting candidate for developing effective medicines for fighting against GIV infection in farmed groupers.
Evaluation of trophic status of Deudap Beach and Lhok Reudeup Beach, Nasi Island, Aceh Province, based on nitrate and phosphate concentration, and chlorophyll-a abundance.
Authors: Ulfah M , Anggraini L , Karina S , Agustina S , Octavina C , Humaira S , Utami D R , Syahliza F , Ramadhan M R , Putra D F , Iqbal T H , Purnawan S , Kurnianda V 
Published: November 2019

Abstract
The investigation of the trophic status based on the nitrate-phosphate correlation and chlorophyll-a abundance in Deudap beach and Lhok Reudup beach, Pulau Nasi, Aceh were carried out in November 2018. Determination of sampling location based on purposive sampling method. The total nitrate, total phosphate concentration, and chlorophyll-a abundance determined by Ultra Violet-Visible (UV-Vis) spectrophotometre which was confirmed from the real-time NOAA database. The results of the chlorophyll-a abundance analysis showed that the abundance of chlorophyll-a in the surface layer ranges 0.7 - 0.11 μg / L. Total nitrate and total phosphate concentrations at deudap beach and lhok reudup in the surface layer ranges 260 - 183 μg / L and 9.4 - 6.8 μg / L. Furthermore, the results indicate that the phenomenon of the chlorophyll-a abundance is closely related to the availability of the macronutrient of nitrate and phosphate. Based on the correlation between total nitrate-phosphate and chlorophyll-a abundance in deudap beach and lhok reudup, Nasi Island are included in the category of oligotrophic waters.
DNA barcoding of snakeskin gourami Trichogaster pectoralis and blue bourami Trichogaster trichopterus based on cythocrome c oxidase subunit I (COI) gene
Authors: Syaifudin M , Jubaedah D , Yonarta D , Hastuti Z 
Published: November 2019

Abstract
Snakeskin gourami Trichogaster pectoralis and blue gourami Trichogaster trichopterus are the species from the genus of Trichogaster. There are three species of the genus Trichogaster in Indonesia. This research aimed to identify the sequence of cytochrome c oxidase subunit I (COI) gene of mtDNA, and construct the phylogenetic trees among species. The stage of research consisted of DNA isolation, DNA amplification using PCR (Polymerase Chain Reaction) and sequencing COI gene in mtDNA region. Sequencing of the COI gene produced 604 bp for snakeskin gourami and 628bp for blue gourami. The result of BLASTn (Basic Local Aligment Search Tool-nucleotide) analysis showed that snakeskin gourami from Kelekar River had 100% similarity of snakeskin from Indonesia and Philippines and farthest (88%) with snakeskin gourami from France. Blue gourami from Inderalaya had 100% similarity with three spot gourami from Australia, South Africa and India and farthest (88%) with snakeskin gourami from Japan. The phylogenetic tree indicated that snakeskin and blue gourami were clustered in separate branches, where snakeskin gourami had 100% similarity to the same species from Indonesia and the Philippines, and blue gourami had 100% identity to the same species from Japan.