bluuebunny/crossref_metadata_2025_split huggingface dataset:
The 2018 Mw7.5 Palu ‘supershear’ earthquake ruptures geological fault's multi-segment separated by large bends: Results from integrating field measurements, LiDAR, swath bathymetry, and seismic-reflection data
Authors: Natawidjaja Danny Hilman , Daryono Mudrik R , Prasetya Gegar , Udrekh  , Liu Philip L-F , Hananto Nugroho Dwi , Kongko Widjo , Triyoso Wahyu , Puji Anggraini Rizkita , Meilano Irwan , Gunawan Endra , Supendi Pepen , Pamumpuni Astyka , Irsyam Mashyur , Faizal Lutfi , Hidayati Sri , Sapiie Benyamin , Kusuma Mipi A , Tawil Sukardan 
Published: October 2020

Summary
On 28 September 2018, 18:02:44 local time, the Magnitude 7.5 earthquake accompanied by a tsunami and massive liquefaction devastated Palu region in Central Sulawesi, Indonesia. Comprehensive post-disaster surveys have been conducted, including field survey of surface ruptures, LiDAR, multibeam-bathymetry mapping, and seismic-reflection survey. We used these data to map fault ruptures and measure offsets accurately. In contrast to previous remote-sensing studies, suggesting that the earthquake broke an immature, hidden-unknown fault inland, our research shows that it occurred on the mappable, mature geological fault line offshore. The quake ruptured 177-km long multi-fault segments, bypassing two large releasing bends (first offshore and second inland). The rupture onset occurred at a large fault discontinuity underwater in a transition zone from regional extensional to compressional tectonic regimes. Then it propagated southward along the ∼110-km submarine fault line before reaching the west side of Palu City. Hence, its long submarine ruptures might trigger massive underwater landslides and significantly contribute to tsunami generation in Palu Bay. The rupture continued inland for another 67 km, showing predominantly left-lateral strike-slip up to 6-m, accompanied by a 5–10% dip-slip on average. The 7km sizeable releasing bend results in a pull-apart Palu basin. Numerous normal faults occur along the eastern margin. They cut the Quaternary sediments, and some of them ruptured during the 2018 event. Our fault-rupture map on mature straight geological fault lines allows the possible occurrence of early and persistent ‘supershear’, but significant asperities and barriers on segment boundaries may prohibit it.
’To cleere the course scarse knowne’: a re-evaluation of Richard Hakluyt’s ‘Voyage of Master Hore’ and the development of English Atlantic enterprise in the early sixteenth century
Authors: Ivinson Joshua 
Published: October 2020

Abstract
This article overturns a century of scholarship concerning Master Hore’s infamous voyage to North America in 1536. Richard Hakluyt’s sensational account of this expedition provided the earliest narrative of an English experience of the New World, which has long been deemed to be corroborated by several High Court of Admiralty documents. However, it is demonstrated here that these sources do not corroborate each other, and that Hakluyt’s account is highly unreliable. More significantly, the existence of two previously unidentified commercial fishing ventures are discovered and analysed, thereby shedding new light on the pioneering mercantile forays of Englishmen across the Atlantic.
Differentiability of Relative Volumes Over an Arbitrary Non-Archimedean Field
Authors: Boucksom Sébastien , Gubler Walter , Martin Florent 
Published: October 2020

AbstractGiven an ample line bundle $L$ on a geometrically reduced projective scheme defined over an arbitrary non-Archimedean field, we establish a differentiability property for the relative volume of two continuous metrics on the Berkovich analytification of $L$, extending previously known results in the discretely valued case. As applications, we provide fundamental solutions to certain non-Archimedean Monge–Ampère equations and generalize an equidistribution result for Fekete points. Our main technical input comes from determinant of cohomology and Deligne pairings.
Silicon induces adventitious root formation in rice under arsenate stress with involvement of nitric oxide and indole-3-acetic acid
Authors: Tripathi Durgesh Kumar , Rai Padmaja , Guerriero Gea , Sharma Shivesh , Corpas Francisco J , Singh Vijay Pratap 
Published: October 2020

Abstract
Arsenic (As) negatively affects plant development. This study evaluates how the application of silicon (Si) can favor the formation of adventitious roots in rice under arsenate stress (AsV) as a mechanism to mitigate its negative effects. The simultaneous application of AsV and Si up-regulated the expression of genes involved in nitric oxide (NO) metabolism, cell cycle progression, auxin (IAA, indole-3-acetic acid) biosynthesis and transport, and Si uptake which accompanied adventitious root formation. Furthermore, Si triggered the expression and activity of enzymes involved in ascorbate recycling. Treatment with L-NAME (NG-nitro L-arginine methyl ester), an inhibitor of NO generation, significantly suppressed adventitious root formation, even in the presence of Si; however, supplying NO in the growth media rescued its effects. Our data suggest that both NO and IAA are essential for Si-mediated adventitious root formation under AsV stress. Interestingly, TIBA (2,3,5-triiodobenzoic acid), a polar auxin transport inhibitor, suppressed adventitious root formation even in the presence of Si and SNP (sodium nitroprusside, an NO donor), suggesting that Si is involved in a mechanism whereby a cellular signal is triggered and that first requires NO formation, followed by IAA biosynthesis.
A catalogue of over 10 million variable source candidates in ZTF Data Release 1
Authors: Ofek Eran O , Soumagnac Maayane , Nir Guy , Gal-Yam Avishay , Nugent Peter , Masci Frank , Kulkarni Shri R 
Published: October 2020

ABSTRACT
Variable sources probe a wide range of astrophysical phenomena. We present a catalogue of over 10 million variable source candidates found in Data Release 1 (DR1) of the Zwicky Transient Facility (ZTF). We perform a periodicity search up to a frequency of 160 d−1, and we classify the light curves into erratic and smooth variables. We also present variability indicators and the results of a periodicity search, up to a frequency of 5 d−1, for about 1 billion sources in the ZTF-DR1 light curve data base. We present several new short-period (&lt;90 min) candidates, and about 60 new dwarf nova candidates, including two candidate eclipsing systems. Both the 10 million variables catalogue and ∼1 billion source catalogue are available online in catsHTM format.
Peryton: a manual collection of experimentally supported microbe-disease associations
Authors: Skoufos Giorgos , Kardaras Filippos S , Alexiou Athanasios , Kavakiotis Ioannis , Lambropoulou Anastasia , Kotsira Vasiliki , Tastsoglou Spyros , Hatzigeorgiou Artemis G 
Published: October 2020

Abstract
We present Peryton (https://dianalab.e-ce.uth.gr/peryton/), a database of experimentally supported microbe-disease associations. Its first version constitutes a novel resource hosting more than 7900 entries linking 43 diseases with 1396 microorganisms. Peryton's content is exclusively sustained by manual curation of biomedical articles. Diseases and microorganisms are provided in a systematic, standardized manner using reference resources to create database dictionaries. Information about the experimental design, study cohorts and the applied high- or low-throughput techniques is meticulously annotated and catered to users. Several functionalities are provided to enhance user experience and enable ingenious use of Peryton. One or more microorganisms and/or diseases can be queried at the same time. Advanced filtering options and direct text-based filtering of results enable refinement of returned information and the conducting of tailored queries suitable to different research questions. Peryton also provides interactive visualizations to effectively capture different aspects of its content and results can be directly downloaded for local storage and downstream analyses. Peryton will serve as a valuable source, enabling scientists of microbe-related disease fields to form novel hypotheses but, equally importantly, to assist in cross-validation of findings.
Carbon nanotubes for flexible batteries: recent progress and future perspective
Authors: Zhu Sheng , Sheng Jian , Chen Yuan , Ni Jiangfeng , Li Yan 
Published: October 2020

Abstract
Flexible batteries, which maintain their functions potently under various mechanical deformations, attract increasing interest due to potential applications in emerging portable and wearable electronics. Significant efforts have been devoted to material synthesis and structural designs to realize the mechanical flexibility of various batteries. Carbon nanotubes (CNTs) have a unique one-dimensional (1D) nanostructure and are convenient to further assemble into diverse macroscopic structures, such as 1D fibers, 2D films and 3D sponges/aerogels. Due to their outstanding mechanical and electrical properties, CNTs and CNT-based hybrid materials are superior building blocks for different components in flexible batteries. This review summarizes recent progress on the application of CNTs in developing flexible batteries, from closed-system to open-system batteries, with a focus on different structural designs of CNT-based material systems and their roles in various batteries. We also provide perspectives on the challenges and future research directions for realizing practical applications of CNT-based flexible batteries.
Impact of Ventilator-associated Pneumonia on Cerebrospinal Fluid Inflammation During Immunosuppression After Subarachnoid Hemorrhage: A Pilot Study
Authors: Coelembier Clément , Venet Fabienne , Demaret Julie , Viel Sébastien , Lehot Jean-Jacques , Dailler Frédéric , Monneret Guillaume , Lukaszewicz Anne-Claire 
Published: October 2020

Introduction:
Brain injuries can cause systemic immunosuppression, which in turn can lead to infections that adversely affect the injured brain and worsen clinical outcomes. This study aimed to investigate whether systemic infection, such as ventilator-associated pneumonia (VAP), induce intracranial inflammation in patients with subarachnoid hemorrhage (SAH).

Methods:
This prospective, observational study included 16 adults with SAH treated in the neuro-intensive care unit. Three paired cerebrospinal fluid samples (obtained from an external ventricular drain) and peripheral blood samples were obtained on days 1 to 3, 4 to 5, and 6 to 7 after SAH onset. Cell counts, cell phenotypes (monocyte HLA-DR, T regulatory cells, lymphocytes, and neutrophils), and inflammatory mediator levels were monitored.

Results:
Six patients developed VAP in the context of systemic immunosuppression demonstrated by a reduction in monocyte HLA-DR expression, lymphopenia, increased percentages of circulating T regulatory cells, and increased proportions of immature and immunosuppressive neutrophil subsets. During VAP, there was de novo recruitment of leukocytes into the cerebrospinal fluid, preferentially neutrophils, which exacerbated intracranial inflammation.

Conclusions:
VAP increased intracranial inflammatory responses in patients with SAH despite the occurrence of systemic immunosuppression. A better understanding of cell trafficking and their pleiotropic functions in brain injury is needed to define the optimal strategies for preventing infections in patients with SAH.
JMJD1C knockdown affects myeloid cell lines proliferation, viability, and gemcitabine/carboplatin-sensitivity
Authors: Schimek Vanessa , Björn Niclas , Pellé Lucia , Svedberg Anna , Gréen Henrik 
Published: October 2020

Objectives
Chemotherapy-induced hematological toxicities are potentially life-threatening adverse drug reactions that vary between individuals. Recently, JMJD1C has been associated with gemcitabine/carboplatin-induced thrombocytopenia in non-small-cell lung cancer patients, making it a candidate marker for predicting the risk of toxicity. This study investigates if JMJD1C knockdown affects gemcitabine/carboplatin-sensitivity in cell lines.

Methods
Lentiviral transduction-mediated shRNA knockdown of JMJD1C in the cell lines K562 and MEG-01 were performed using shRNA#32 and shRNA#33. The knockdown was evaluated using qPCR. Cell proliferation, viability, and gemcitabine/carboplatin-sensitivity were subsequently determined using cell counts, trypan blue, and the MTT assay.

Results
ShRNA#33 resulted in JMJD1C downregulation by 56.24% in K562 and 68.10% in MEG-01. Despite incomplete knockdown, proliferation (reduction of cell numbers by 61–68%, day 7 post-transduction) and viability (reduction by 21–53%, day 7 post-transduction) were impaired in K562 and MEG-01 cells. Moreover, JMJD1C knockdown reduced the gemcitabine IC50-value for K562 cells (P < 0.01) and MEG-01 cells (P < 0.05) compared to scrambled shRNA control transduced cells.

Conclusions
Our results suggest that JMJD1C is essential for proliferation, survival, and viability of K562 and MEG-01 cells. Further, JMJD1C also potentially affects the cells gemcitabine/carboplatin-sensitivity. Although further research is required, the findings show that JMJD1C could have an influential role for gemcitabine/carboplatin-sensitivity.
Relationship and Effects of Community Problems on Anxiety and Suicide
Authors: Lyu Juncheng , Ding Li , Zhang Jie 
Published: October 2020

Abstract
This study aimed to explore the relationship and the effects of community problems on anxiety and suicide. Data were from a case-control psychological autopsy study (392 suicides and 416 community living controls) carried out in 16 rural counties from three provinces in China. The World Health Organization Suicide Prevention–Multisite Intervention Study on Suicidal behaviors scale of community stress and problems and Spielberger State-Trait Anxiety Inventory were used to measure the community problems and trait anxiety. Spearman's correlation and multivariable regression methods were used to probe the effect of community problems on anxiety and suicide. There were 12 and 6 community problems correlated with anxiety (r
s = 0.169, p < 0.001) and suicide (r
s = 0.081, p = 0.022), respectively. Medical care, alcohol abuse, superstition, and job security were important community problems for anxiety and suicide. Community problems had stronger correlation with anxiety than suicide. It might be an effective method to reduce anxiety and suicide risk by solving different community problems.
Clinical and economic impact of bacterial resistance: an approach to infection control and antimicrobial stewardship solutions
Authors: Calbo Esther , Boix-Palop Lucía , Garau Javier 
Published: October 2020

Purpose of review
The aim of this study was to describe the clinical and economic burden of bacterial antimicrobial resistance (AMR) and to provide an expert opinion on different approaches to fight it.

Recent findings
For several decades now, it has been known that AMR among human pathogens is related to high clinical and economic burden.
Different strategies have been implemented to control the clinical and economic burden of AMR. Antimicrobial stewardship programmes (ASP), environmental cleaning and infection source control have been reported as the most effective interventions. There is a potential role for faecal microbiome transplant (FMT); however, long-term effectiveness and safety remain to be demonstrated. Another promising tool is to develop molecules to chelate or degrade residual antibiotics in the colon. Decolonization has demonstrated impact on methicillin-resistant Staphylococcus aureus (MRSA) infections, but there is limited evidence on the clinical impact and effectiveness of decolonization in MDR Gram-negative carriers.

Summary
A better assessment of AMR rates and the clinical and economic impact is needed. The epidemiology of AMR bacteria varies in different regions with MRSA, extended-spectrum beta-lactamase and carbapenamase-producing Enterobacterales being the most worrying. ASP and infection control have been increasingly demonstrated to impact on AMR rates. New approaches such as FMT and decolonization have still to demonstrate efficacy and safety.
Molecular MR Contrast Agents
Authors: Shuvaev Sergey , Akam Eman , Caravan Peter 
Published: October 2020

Abstract
Molecular magnetic resonance (MR) imaging utilizes molecular probes to provide added biochemical or cellular information to what can already be achieved with anatomical and functional MR imaging. This review provides an overview of molecular MR and focuses specifically on molecular MR contrast agents that provide contrast by shortening the T1 time. We describe the requirements for a successful molecular MR contrast agent and the challenges for clinical translation. The review highlights work from the last 5 years and places an emphasis on new contrast agents that have been validated in multiple preclinical models. Applications of molecular MR include imaging of inflammation, fibrosis, fibrogenesis, thromboembolic disease, and cancers. Molecular MR is positioned to move beyond detection of disease to the quantitative staging of disease and measurement of treatment response.
Heating of Hip Arthroplasty Implants During Metal Artifact Reduction MRI at 1.5- and 3.0-T Field Strengths
Authors: Khodarahmi Iman , Rajan Sunder , Sterling Robert , Koch Kevin , Kirsch John , Fritz Jan 
Published: October 2020

Objectives
The aim of this study was to quantify the spatial temperature rises that occur during 1.5- and 3.0-T magnetic resonance imaging (MRI) of different types of hip arthroplasty implants using different metal artifact reduction techniques.

Materials and Methods
Using a prospective in vitro study design, we evaluated the spatial temperature rises of 4 different total hip arthroplasty constructs using clinical metal artifact reduction techniques including high-bandwidth turbo spin echo (HBW-TSE), slice encoding for metal artifact correction (SEMAC), and compressed sensing SEMAC at 1.5 and 3.0 T. Each MRI protocol included 6 pulse sequences, with imaging planes, parameters, and coverage identical to those in patients. Implants were immersed in standard American Society for Testing and Materials phantoms, and fiber optic sensors were used for temperature measurement. Effects of field strength, radiofrequency pulse polarization at 3.0 T, pulse protocol, and gradient coil switching on heating were assessed using nonparametric Friedman and Wilcoxon signed-rank tests.

Results
Across all implant constructs and MRI protocols, the maximum heating at any single point reached 13.1°C at 1.5 T and 1.9°C at 3.0 T. The temperature rises at 3.0 T were similar to that of background in the absence of implants (P = 1). Higher temperature rises occurred at 1.5 T compared with 3.0 T (P < 0.0001), and circular compared with elliptical radiofrequency pulse polarization (P < 0.0001). Compressed sensing SEMAC generated equal or lower degrees of heating compared with HBW-TSE at both field strengths (P < 0.0001).

Conclusions
Magnetic resonance imaging of commonly used total hip arthroplasty implants is associated with variable degrees of periprosthetic tissue heating. In the absence of any perfusion effects, the maximum temperature rises fall within the physiological range at 3.0 T and within the supraphysiologic range at 1.5 T. However, with the simulation of tissue perfusion effects, the heating at 1.5 T also reduces to the upper physiologic range. Compressed sensing SEMAC metal artifact reduction MRI is not associated with higher degrees of heating than the HBW-TSE technique.
Accessory and Incomplete Lung Fissures
Authors: Bayter Paula A. , Lee Gregory M. , Grage Rolf A. , Walker Christopher M. , Suster David I. , Greene Reginald E. , Gilman Matthew D. , Lanuti Michael , Stowell Justin T. 
Published: October 2020

Objective:
This article reviews the anatomy, histology, and disease processes of pulmonary fissures, with emphasis on clinical implications of accessory and incomplete fissures.

Conclusion:
Accessory and incomplete pulmonary fissures are often overlooked during routine imaging but can have profound clinical importance. Knowledge of fissure anatomy could improve diagnostic accuracy and inform prognosis for oncologists, interventional pulmonologists, and thoracic surgeons.
Conceptual developments in sperm competition: a very brief synopsis
Authors: Parker Geoff A. 
Published: October 2020

The past half century has seen the development of the field of post-ejaculatory sexual selection, the sequel to sexual selection for mate-acquisition (pre-ejaculatory) described by Darwin. In richness and diversity of adaptations, post-ejaculatory selection rivals that of pre-ejaculatory sexual selection. Anisogamy—and hence two sexes—likely arose by primeval gamete competition, and sperm competition remains a major force maintaining high sperm numbers. The post-ejaculatory equivalent of male–male competition for matings, sperm competition was an intense ancestral form of sexual selection, typically weakening as mobility and internal fertilization developed in many taxa, when some expenditure became diverted into pre-ejaculatory competition. Sperm competition theory has been relatively successful in explaining variation in relative testes size and sperm numbers per ejaculate and is becoming more successful in explaining variation in sperm phenotype. Sperm competition has generated many other male adaptations such as seminal fluid proteins that variously modify female reproduction towards male interests, and copulatory plugs, prolonged copulations and post-ejaculatory guarding behaviour that reduce female remating probability, many of which result in sexual conflict. This short survey of conceptual developments is intended as a broad overview, mainly as a primer for new researchers.This article is part of the theme issue ‘Fifty years of sperm competition'.
Evolutionary insight from a humble fly: sperm competition and the yellow dungfly
Authors: Simmons Leigh W. , Parker Geoff A. , Hosken David J. 
Published: October 2020

Studies of the yellow dungfly in the 1960s provided one of the first quantitative demonstrations of the costs and benefits associated with male and female reproductive behaviour. These studies advanced appreciation of sexual selection as a significant evolutionary mechanism and contributed to the 1970s paradigm shift toward individual selectionist thinking. Three behaviours in particular led to the realization that sexual selection can continue during and after mating: (i) female receptivity to remating, (ii) sperm displacement and (iii) post-copulatory mate guarding. These behaviours either generate, or are adaptations to sperm competition, cryptic female choice and sexual conflict. Here we review this body of work, and its contribution to the development of post-copulatory sexual selection theory.
This article is part of the theme issue ‘Fifty years of sperm competition’.
Within-ejaculate sperm competition
Authors: Sutter Andreas , Immler Simone 
Published: October 2020

Sperm competition was defined by Geoff Parker 50 years ago as the competition between sperm from two or more males over the fertilization of a set of eggs. Since the publication of his seminal paper, sperm competition has developed into a large field of research, and many aspects are still being discovered. One of the relatively poorly understood aspects is the importance of selection and competition among sperm within the ejaculate of a male. The sheer number of sperm present in a male's ejaculate suggests that the competition among sibling sperm produced by the same male may be intense. In this review, we summarize Parker's theoretical models generating predictions about the evolution of sperm traits under the control of the haploid gamete as opposed to the diploid male. We review the existing evidence of within-ejaculate competition from a wide range of fields and taxa. We also discuss the conceptual and practical hurdles we have been facing to study within-ejaculate sperm competition, and how novel technologies may help in addressing some of the currently open questions.
This article is part of the theme issue ‘Fifty years of sperm competition’.