bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geometry of Horospherical Varieties of Picard Rank One
Authors: Gonzales R , Pech C , Perrin N , Samokhin A 
Published: October 2020

AbstractWe study the geometry of smooth non-homogeneous horospherical varieties of Picard rank one. These have been classified by Pasquier and include the well-known odd symplectic Grassmannians. We focus our study on quantum cohomology, with a view towards Dubrovin’s conjecture. We start with describing the cohomology groups of smooth horospherical varieties of Picard rank one. We show a Chevalley formula for these and establish that many Gromov–Witten invariants are enumerative. This enables us to prove that in many cases the quantum cohomology is semisimple. We give a presentation of the quantum cohomology ring for odd symplectic Grassmannians. In the last sections, we turn to derived categories of coherent sheaves. We first discuss a general construction of exceptional bundles on horospherical varieties. We work out in detail the case of the horospherical variety associated to the exceptional group $G_2$ and construct a full rectangular Lefschetz exceptional collection in the derived category.
Differences in Factors Associated With High- and Low-Risk Oral Human Papillomavirus Genotypes in Men
Authors: Bettampadi Deepti , Dickey Brittney , Abrahamsen Martha , Sirak Bradley , Baggio Maria Luiza , Galan Lenice , Silva Roberto Carvalho , Villa Luisa , Ponce Eduardo Lazcano , Giuliano Anna R 
Published: October 2020

Abstract

Background
Human papillomavirus (HPV) causes oral warts and oropharyngeal cancer (OPC). Human papillomavirus-attributable OPC incidence among men is significantly increasing worldwide, yet few studies have reported oral HPV across multiple countries or examined factors associated with low- and high-risk HPV separately.

Methods
Oral gargles from 3095 men in the multinational HPV Infection in Men (HIM) Study were HPV genotyped. Multivariable models assessed factors independently associated with high-risk and low-risk HPV prevalence.

Results
The prevalence of high-risk and low-risk HPV was 6.0% and 2.8%, respectively. Greater number of sexual partners was only associated with high-risk HPV (1.88; 95% confidence interval [CI], 1.22–2.90) prevalence. In multivariable models, residing in Mexico (1.66; 95% CI, 1.15–2.40) and smoking (1.66; 95% CI, 1.13–2.44) were significantly associated with high-risk HPV, and history of consistent gum bleeding (2.16; 95% CI, 1.35–3.45) was significantly associated with low-risk HPV. Gender of the sexual partner did not alter the results for either high- or low-risk HPV endpoints.

Conclusions
Different factors were independently associated with high- and low-risk oral HPV. Oral sexual behaviors were associated with high-risk HPV, and oral health was associated with low-risk HPV. High-risk HPV prevalence differed by country of residence, highlighting the need for additional studies in multiple countries.
Patient Diversity in Breast Imaging: Barriers and Potential Solutions
Authors: Patel Miral M , Parikh Jay R 
Published: October 2020

Abstract
Recent reports have highlighted disparities in breast cancer care related to patient diversity. Breast radiologists represent the face of breast imaging and are key players in advocating for patients to reduce these disparities. Diversity-related barriers for breast imaging patients, as they journey from screening to survivorship, include impediments to access and quality of care, gaps in communication, and lack of knowledge in both providers and patients. Potential strategies for overcoming these specific barriers include “culturally tailored” nurse navigators, mobile mammography, improved communication, patient and provider education, and breast radiologist involvement in advocacy efforts promoting diversity. As current trends in recommendations and guidelines for breast imaging include more numerous and advanced imaging modalities, it is important to acknowledge and address diversity-related disparities.
The CTSC-RAB38 Fusion Transcript Is Associated With the Risk of Hemorrhage in Brain Arteriovenous Malformations
Authors: Yan Zihan , Fan Guangming , Li Hao , Jiao Yuming , Fu Weilun , Weng Jiancong , Huo Ran , Wang Jie , Xu Hongyuan , Wang Shuo , Cao Yong , Zhao Jizong 
Published: October 2020

Abstract
Brain arteriovenous malformations (bAVMs) are congenital anomalies of blood vessels that cause intracranial hemorrhage in children and young adults. Chromosomal rearrangements and fusion genes play an important role in tumor pathogenesis, though the role of fusion genes in bAVM pathophysiological processes is unclear. The aim of this study was to identify fusion transcripts in bAVMs and analyze their effects. To identify fusion transcripts associated with bAVM, RNA sequencing was performed on 73 samples, including 66 bAVM and 7 normal cerebrovascular samples, followed by STAR-Fusion analysis. Reverse transcription polymerase chain reaction and Sanger sequencing were applied to verify fusion transcripts. Functional pathway analysis was performed to identify potential effects of different fusion types. A total of 21 fusion transcripts were detected. Cathepsin C (CTSC)-Ras-Related Protein Rab-38 (RAB38) was the most common fusion and was detected in 10 of 66 (15%) bAVM samples. In CTSC-RAB38 fusion-positive samples, CTSC and RAB38 expression was significantly increased and activated immune/inflammatory signaling. Clinically, CTSC-RAB38 fusion bAVM cases had a higher hemorrhage rate than non-CTSC-RAB38 bAVM cases (p &lt; 0.05). Our study identified recurrent CTSC-RAB38 fusion transcripts in bAVMs, which may be associated with bAVM hemorrhage by promoting immune/inflammatory signaling.
What prospects for shale gas in Asia? Case of shale gas in China
Authors: Le Minh Thong , Do Huu Tung , Nguyen Thanh Thuy , Nguyen Thi Kim Ngan 
Published: October 2020

Abstract
The issues of energy and the environment are one of the main challenges for humanity today. Global growth in energy demand is facing environmental concerns, especially in fast-growing regions such as Asia. Transferring traditional energy sources such as coal, oil, to cleaner energy sources and renewables is an inevitable trend in the future. With good characteristics compared to other fossil fuels, natural gas can play an essential role in the energy transition process towards a low-carbon economy. The success of the shale gas revolution in the USA has created a lot of interest globally, especially in countries with potential for these resources. Asia, especially China, is estimated to have the world's largest shale gas resource. However, the question about the development of these resources is still a big question. This article will evaluate shale gas development prospects in Asia, particularly in China, by analysing the fundamental conditions that are important factors for the success of shale gas in the USA.
Point-of-Care Testing Effectiveness on Blood Donor Hemoglobin Testing
Authors: Grech Kayleigh , Zammit Vanessa 
Published: October 2020

AbstractBackgroundHemoglobin (Hb) evaluation by point-of-care testing (POCT) identifies borderline or anaemic asymptomatic blood donors. Although quality control checks confirm that this device is fit for use, it is still not clear whether the analyser is performing effectively. A protocol comparing the POCT EKF Diagnostics with the Sysmex XN-550 automated cell counter (ACC) has been designed.MethodsVarious scenarios of Hb measurements from the ACC and the POCT device are compared using the Spearman correlation and Intraclass correlation. The Bland-Altman method was used to analyse the level of agreement between the two devices.ResultsCorrelation between the two devices was best observed in the venous vs venous blood scenario.ConclusionThe POCT device overestimates the Hb levels in capillary blood, meaning that Hb requirements should be adjusted and when feasible testing repeated on venous blood using an ACC. Furthermore, it is suggested thar each Facility determine their own Hb threshold.
Visual exploration of historical maps
Authors: Reckziegel Martin , Wrisley David Joseph , Hixson Taylor Wright , Jänicke Stefan 
Published: October 2020

AbstractHistorical maps tell rich stories, and they are also valuable data objects. They vary greatly in size, type, and context, as well as the kinds and density of information they contain. Historical maps are indeed objects that invite close reading, interpretation, and debate. Whereas a variety of environments exist for the annotation, manipulation, and representation of digital maps, or map-derived data, workflows in the spatial digital humanities can be complex and those environments are not often well integrated. In this article, we describe a prototype named ‘MapFolder’ for studying maps, its algorithms for calculating the areal distortion, its visual design for communicating that distortion, along with a scholarly workflow. We blend annotation practices common in the spatial humanities with the workflows of georeferencing in order to be able to visualize how historic cartographic documents compare with the geospatial representations we are familiar with today. The case studies we use to demonstrate ‘MapFolder’ are maps of the medieval period, a body of maps that are less often studied algorithmically and that are usually avoided in typical workflows of georeferencing. MapFolder is by no means a prototype designed to work exclusively with medieval maps, but since maps of this period are only partially geographic in their design, they offer a particularly fruitful opportunity to rethink the algorithmic manipulation of historical depictions of the world. Working with this complex data from the humanities allows us, as well, to propose the use of visualization for critical, comparative spatial analysis in pre-modern studies and beyond.
The Metal Abundances across Cosmic Time (MACT) Survey. III – The relationship between stellar mass and star formation rate in extremely low-mass galaxies
Authors: Shin Kaitlyn , Ly Chun , Malkan Matthew A , Malhotra Sangeeta , de los Reyes Mithi , Rhoads James E 
Published: October 2020

ABSTRACT
Extragalactic studies have demonstrated that there is a moderately tight (≈0.3 dex) relationship between galaxy stellar mass (M⋆) and star formation rate (SFR) that holds for star-forming galaxies at M⋆ ∼ 3 × 108–1011 M⊙, i.e. the ‘star formation main sequence’. However, it has yet to be determined whether such a relationship extends to even lower mass galaxies, particularly at intermediate or higher redshifts. We present new results using observations for 714 narrow-band H α-selected galaxies with stellar masses between 106 and 1010 M⊙ (average of 108.2 M⊙) at z ≈ 0.07–0.5. These galaxies have sensitive ultraviolet (UV) to near-infrared photometric measurements and optical spectroscopy. The latter allows us to correct our H α SFRs for dust attenuation using Balmer decrements. Our study reveals that: (1) for low-SFR galaxies, our H α SFRs systematically underpredict compared to far-UV measurements, consistent with other studies; (2) at a given stellar mass (≈108 M⊙), log (specific SFR) evolves as A log (1 + z) with A = 5.26 ± 0.75, and on average, specific SFR increases with decreasing stellar mass; (3) the SFR–M⋆ relation holds for galaxies down to ∼106 M⊙ (∼1.5 dex below previous studies), and over lookback times of up to 5 Gyr, follows a redshift-dependent relation of log (SFR) ∝ α log (M⋆/M⊙) + β z with α = 0.60 ± 0.01 and β = 1.86 ± 0.07; and (4) the observed dispersion in the SFR–M⋆ relation at low stellar masses is ≈0.3 dex. Accounting for survey selection effects using simulated galaxies, we estimate that the true dispersion is ≈0.5 dex.
Simulations of globular clusters within their parent galaxies: multiple stellar populations and internal kinematics
Authors: McKenzie Madeleine , Bekki Kenji 
Published: October 2020

ABSTRACT
Using three-dimensional smoothed particle hydrodynamics simulations, we investigate the formation of multiple stellar populations (MSPs) in globular clusters (GCs) within the context of their parent galaxies. In our scenario, the second generation (2G) of stars originate from both asymptotic giant branch (AGB) polluters and pristine gas accreted from the host galaxy. Previous theoretical and numerical studies have demonstrated that this ‘AGB with dilution’ model has the potential to alleviate several problems faced by the classical AGB scenario. However, the accretion of pristine gas on to the GC has yet to be investigated within the context of the parent galaxy. This paper presents the preliminary results from our original simulation code which models GC formation from giant molecular clouds in a host galaxy, and subsequent gas accretion on to the GC. By simulating the genesis of the 2G over a 370 Myr time frame, we demonstrate that the fraction of 2G stars are inextricably linked to the GC’s environment. Our simulations rationalize the wide variety of abundance patterns, kinematics, and 2G concentrations by altering the initial conditions of both the GC progenitor and the host galaxy itself. Most notably, we reproduce a positive correlation between the fraction of 2G stars and the initial mass of the cluster. We discuss the physical implications of our scenario and compare our simulations with observations of the Galactic GC 47 Tucanae (47 Tuc). Finally, we present scaling relations that encompass the wider GC population and serve as a reference for future observations.
Unveiling early black hole growth with multifrequency gravitational wave observations
Authors: Valiante Rosa , Colpi Monica , Schneider Raffaella , Mangiagli Alberto , Bonetti Matteo , Cerini Giulia , Fairhurst Stephen , Haardt Francesco , Mills Cameron , Sesana Alberto 
Published: October 2020

ABSTRACT
Third-generation ground-based gravitational wave interferometers, like the Einstein Telescope (ET), Cosmic Explorer, and the Laser Interferometer Space Antenna (LISA), will detect coalescing binary black holes over a wide mass spectrum and across all cosmic epochs. We track the cosmological growth of the earliest light and heavy seeds that swiftly transit into the supermassive domain using a semi-analytical model for the formation of quasars at z = 6.4, 2, and 0.2, in which we follow black hole coalescences driven by triple interactions. We find that light-seed binaries of several $10^2 \, {\rm M_\odot }$ are accessible to ET with a signal-to-noise ratio (S/N) of 10–20 at 6 &lt; z &lt; 15. They then enter the LISA domain with larger S/N as they grow to a few $10^4 \, {\rm M_\odot }$. Detecting their gravitational signal would provide first time evidence that light seeds form, grow, and dynamically pair during galaxy mergers. The electromagnetic emission of accreting black holes of similar mass and redshift is too faint to be detected even for the deepest future facilities. ET will be our only chance to discover light seeds forming at cosmic dawn. At 2 &lt; z &lt; 8, we predict a population of ‘starved binaries’, long-lived marginally growing light-seed pairs, to be loud sources in the ET bandwidth (S/N &gt; 20). Mergers involving heavy seeds (${\sim} 10^5\!-\!10^6 \, {\rm M_\odot }$) would be within reach up to z = 20 in the LISA frequency domain. The lower z model predicts $11.25 \, (18.7)$ ET (LISA) events per year, overall.
Exploring the hot gaseous halo around an extremely massive and relativistic jet launching spiral galaxy with XMM−Newton
Authors: Mirakhor M S , Walker S A , Bagchi J , Fabian A C , Barth A J , Combes F , Dabhade P , Ho L C , Pandge M B 
Published: October 2020

ABSTRACT
We present a deep XMM−Newton observation of the extremely massive, rapidly rotating, relativistic-jet-launching spiral galaxy 2MASX J23453268−0449256. Diffuse X-ray emission from the hot gaseous halo around the galaxy is robustly detected out to a radius of 160 kpc, corresponding roughly to 35 per cent of the virial radius (≈450 kpc). We fit the X-ray emission with the standard isothermal β model, and it is found that the enclosed gas mass within 160 kpc is $1.15_{-0.24}^{+0.22} \times 10^{11} \, \rm {M}_{\odot }$. Extrapolating the gas mass profile out to the virial radius, the estimated gas mass is $8.25_{-1.77}^{+1.62} \times 10^{11} \, \rm {M}_{\odot }$, which makes up roughly 65 per cent of the total baryon mass content of the galaxy. When the stellar mass is considered and accounting for the statistical and systematic uncertainties, the baryon mass fraction within the virial radius is $0.121_{-0.043}^{+0.043}$, in agreement with the universal baryon fraction. The baryon mass fraction is consistent with all baryons falling within r200, or with only half of the baryons falling within r200. Similar to the massive spiral galaxies NGC 1961 and NGC 6753, we find a low value for the metal abundance of ≈ 0.1 Z⊙, which appears uniform with radius. We also detect diffuse X-ray emission associated with the northern and southern lobes, possibly attributed to inverse Compton scattering of cosmic microwave background photons. The estimated energy densities of the electrons and magnetic field in these radio lobes suggest that they are electron-dominated by a factor of 10−200, depending on the choice of the lower cut-off energy of the electron spectrum.
Urinary mulberry bodies as a potential biomarker for early diagnosis and efficacy assessment of enzyme replacement therapy in Fabry nephropathy
Authors: Yonishi Hiroaki , Namba-Hamano Tomoko , Hamano Takayuki , Hotta Masaki , Nakamura Jun , Sakai Shinsuke , Minami Satoshi , Yamamoto Takeshi , Takahashi Atsushi , Kobayashi Wataru , Maeda Ikuhiro , Hidaka Yoh , Takabatake Yoshitsugu , Sakai Norio , Isaka Yoshitaka 
Published: October 2020

Abstract

Background
The inability of enzyme replacement therapy (ERT) to prevent progression of Fabry nephropathy (FN) in the presence of &gt;1 g/day proteinuria underscores the necessity of identifying effective biomarkers for early diagnosis of FN preceding proteinuria. Here we attempted to identify biomarkers for early detection of FN.

Methods
Fifty-one Fabry disease (FD) patients were enrolled. Urinary mulberry bodies (uMBs) were immunostained for globotriaosylceramide (Gb3) and renal cell markers to determine their origin. The association between semiquantitative uMB excretion and the histological severity of podocyte vacuolation was investigated in seven patients using the vacuolated podocyte:glomerular average area ratio. The association between the semiquantitative estimate of uMB excretion and duration of ERT was analyzed. A longitudinal study was conducted to assess the effect of ERT on uMB excretion.

Results
Thirty-two patients (63%) had uMBs, while only 31% showed proteinuria. The uMBs were positive for Gb3, lysosomal-associated membrane protein 1 and podocalyxin, suggesting they were derived from lysosomes with Gb3 accumulation in podocytes. We observed more severe podocyte vacuolation with increased uMB excretion (P = 0.03 for trend); however, the same was not observed with increased proteinuria. The percentage of patients with substantial uMB excretion increased with shorter ERT duration (P = 0.018). Eighteen-month-long ERT reduced uMB excretion (P = 0.03) without affecting proteinuria.

Conclusions
uMB excretion, implying ongoing podocyte injury, preceded proteinuria in most patients. Semiquantitative uMB estimates can serve as novel biomarkers for early FN diagnosis and for monitoring the efficacy of FD-specific therapies.
Cruciferous vegetables: rationale for exploring potential salutary effects of sulforaphane-rich foods in patients with chronic kidney disease
Authors: Cardozo Ludmila F M F , Alvarenga Livia A , Ribeiro Marcia , Dai Lu , Shiels Paul G , Stenvinkel Peter , Lindholm Bengt , Mafra Denise 
Published: October 2020

AbstractSulforaphane (SFN) is a sulfur-containing isothiocyanate found in cruciferous vegetables (Brassicaceae) and a well-known activator of nuclear factor-erythroid 2-related factor 2 (Nrf2), considered a master regulator of cellular antioxidant responses. Patients with chronic diseases, such as diabetes, cardiovascular disease, cancer, and chronic kidney disease (CKD) present with high levels of oxidative stress and a massive inflammatory burden associated with diminished Nrf2 and elevated nuclear transcription factor-κB-κB expression. Because it is a common constituent of dietary vegetables, the salutogenic properties of sulforaphane, especially it’s antioxidative and anti-inflammatory properties, have been explored as a nutritional intervention in a range of diseases of ageing, though data on CKD remain scarce. In this brief review, the effects of SFN as a senotherapeutic agent are described and a rationale is provided for studies that aim to explore the potential benefits of SFN-rich foods in patients with CKD.
Association between seasonal flu vaccination and COVID-19 among healthcare workers
Authors: Belingheri M , Paladino M E , Latocca R , De Vito G , Riva M A 
Published: October 2020

Abstract

Background
In next fall and winter, SARS-CoV-2 could circulate in parallel with seasonal influenza. The dual epidemics will result in considerable morbidity and mortality; therefore, influenza vaccination may be essential. Recent studies found increased risk of coronavirus in individuals receiving influenza vaccination.

Aims
Our aim is to analyse the association between influenza vaccination and COVID-19 in a population of healthcare workers (HCWs).

Methods
IgG antibodies against SARS-CoV-2 were detected in 3520 HCWs at a large hospital in Northern Italy. For each participant, we collected data on flu immunization status for the last five flu seasons. Logistic regression was used to test associations between seasonal flu vaccination status and a positive serology tests for COVID-19.

Results
During the last five flu seasons, 2492 vaccinations were administered. Serology tests were negative for 3196 (91%) HCWs and residents and only 21 (1%) people had an equivocal test (12.0–15.0 AU/mL). Only 128 (4%) people received a diagnosis of COVID-19, with a positive swab test. No flu vaccinations for the last five flu seasons were specifically associated with diagnosis of COVID-19 or with positive results of serology tests.

Conclusions
Flu vaccinations did not appear to be associated with SARS-CoV-2 infection. Influenza vaccination should continue to be recommended for HCWs and for individuals at increased risk for severe illness from respiratory infection.
Wages and Firm Performance: Evidence from the 2008 Financial Crisis
Authors: Ouimet Paige , Simintzi Elena 
Published: October 2020

Abstract
We examine the effect of higher wages on firm performance during the 2008 financial crisis. To identify variation in wages, we rely on heterogeneity in the timing of long-term wage agreements for a sample of U.K. firms. We instrument for firms signing long-term agreements overlapping with the crisis by the presence of a contract signed in 2006 or earlier and expiring before September 2008. Treated firms not only paid higher wages but also realized greater labor productivity relative to control firms. These findings are consistent with the intuition that opportunity cost differentials between treated and control firms induce employees to exert higher effort. (JEL J41, J30, J24, G01)
Received February 28, 2019; editorial decision July 8, 2020 by Editor Andrew Ellul. Authors have furnished an Internet Appendix, which is available on the Oxford University Press Web site next to the link to the final published paper online.
Common Ownership and Corporate Social Responsibility
Authors: Dai Xin , Qiu Yue 
Published: October 2020

Abstract
This paper studies the effect of common ownership on corporate social responsibility (CSR). We find that common ownership is positively associated with a firm’s CSR score. The effect is stronger for firms in more competitive industries. We propose a two-stage duopoly game in which CSR serves as a commitment device to expand output aggressively to understand the empirical results. (JEL G30, D21, D22, L13, L21, L22)
Received December 10, 2019; editorial decision September 9, 2020 by Editor: Gregor Matvos. Authors have furnished an Internet Appendix, which is available on the Oxford University Press Web site next to the link to the final published paper online.