bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical case report on Smokeless Tobacco Keratosis
Authors: Thakur Dr. Vishal , Kaur Dr. Manpreet , Jassal Dr. Supriya 
Published: October 2020

Smokeless tobacco keratosis is a condition that causes thick white patches to form on mucosa with common sites are inner check , in between teeth & gums , appear wrinkled in texture usually develops in between 1-5 years of tobacco use. Educating and motivating a patient is very important in the prevention as well as cure of STK.
Identification of B cell antigenome in Mycobacterium bovis by immunoproteomic analysis
Authors: Cho Yun Sang , Lee Sang Eun , Jang Youngboo , Jung Sukchan , Kim Jong Man 
Published: October 2020

AbstractBovine tuberculosis (bTB) is a common zoonosis prevalent in many countries with grave economic consequences. Most developed and developing countries have implemented the test-and-slaughter policy to protect public health and reduce economic losses in the cattle industry. The official diagnosis of bTB is based on assays dependent on cell-mediated immunity (CMI). CMI-based diagnosis demonstrates diagnostic incapability at late stages of infection, which could be overcome by diagnosis based on humoral immunity (HI). Therefore, there is an urgent need to identify and define the B cell antigenome of Mycobacterium bovis. In this study, the B cell antigenome of culture filtrate proteins (CFP) was defined by mass spectrometry-based proteomics technology. Four spots were detected on 2-dimensional gel electrophoresis (2-DE) against M. bovis-positive serum in an immunoblotting experiment. Twenty-one proteins were identified in four spots by proteomic tools, such as Mb2900, Mb2898, Mb0448, Mb3834c, Mb1918c, Mb0134c, Mb0358 and Mb1868c, which are known B cell antigens, including 13 new proteins, i.e. Mb3751, Mb2006c, Mb3276c, Mb2244, Mb1164c, Mb2553c, Mb2946c, Mb1849c, Mb1511c, Mb1034c, Mb2616c, Mb0854c and Mb2267. These new proteins identified by 2-DE and immunoblotting were the B cell antigens used in developing serological diagnostic methods based on HI to bTB.
Improvement of the clinical signs of gait abnormality after treatment with levothyroxine in a horse with shivering and hypothyroidism
Authors: Saadi Aram , Dalir-Naghadeh Bahram , Akbari Hamid , Rashedi Mojtaba , Mohammadi Rahim 
Published: October 2020

AbstractAn 11-year-old Hanoverian gelding used for jumping was evaluated for gait abnormalities and hoof problems in the hindlimbs. Clinical examinations revealed signs consistent with shivers. A thyroid gland enlargement was noticed, baseline serum thyroid hormone (TH) concentrations were low, and a low response to thyrotropin-releasing hormone administration was observed. Hypothyroidism was suspected. The horse was treated with levothyroxine for 1 year. TH concentrations returned to the normal range by week 4 of treatment. Thirty weeks after the initiation of levothyroxine therapy, the gait abnormality improved. Our findings suggest that the assessment of thyroid status and especially of the subclinical thyroid gland disorders in horses affected with shivering, as well as evaluation of the effects of levothyroxine on the improvement of clinical signs could be promising in establishing the aetiopathogenesis and/or treatment of shivering in horses.
Changes in the expression of substance P in nerve fibres of the colonic mucosa in dogs suffering from inflammatory bowel disease
Authors: Rychlik Andrzej , Gonkowski Slawomir , Makowska Krystyna , Kaczmar Ewa , Calka Jaroslaw 
Published: October 2020

AbstractDue to its difficult diagnosis and complicated treatment, inflammatory bowel disease (IBD) in dogs is a challenge for the veterinarian. Several aspects connected with pathological changes during IBD still remain unknown. Since one of these aspects is the participation of intestinal innervation in the evolution of the disease, the aim of this study was to demonstrate changes in the number and distribution of intramucosal colonic nerve fibres immunoreactive to substance P (SP) arising as the disease progresses. SP is one of the most important neuronal factors in intestinal innervation which, among other tasks, takes part in the conduction of pain stimuli. Using routine immunofluorescence technique, the density of nerve fibres containing SP was evaluated within mucosal biopsy specimens collected from the descending colon of healthy dogs and animals suffering from IBD of varying severity. The results of the study indicate that during severe IBD the number of nerve fibres containing SP located in the colonic mucosal layer increases in comparison to control animals. The number of SP-positive intramucosal nerves amounted to 10.99 ± 2.11 nerves per observation field in healthy dogs, 14.62 ± 2.86 in dogs with mild IBD, 14.80 ± 0.91 in dogs with moderate IBD and 19.03 ± 6.11 in animals with severe IBD. The observed changes were directly proportional to the intensity of the disease process. These observations may suggest a role of this neuronal substance in pathological processes occurring during IBD. Although the exact mechanism of the observed changes has not been completely explained, the results obtained in this investigation may contribute to improving the diagnosis and treatment of this disease, as well as the staging of canine IBD in veterinary practice.
Praxis‐induced reflex seizures in two Japanese cases with ring chromosome 20 syndrome
Authors: Yamagishi Hirokazu , Goto Masahide , Osaka Hitoshi , Kuwajima Mari , Muramatsu Kazuhiro , Yamagata Takanori 
Published: October 2020

ABSTRACTRing chromosome 20 syndrome is an epileptic and neurodevelopmental encephalopathy that occurs in children, characterised by a triad of refractory frontal lobe seizures, recurrent non‐convulsive status epilepticus and frontal lobe‐dominant paroxysmal discharges. However, details of other clinical features associated with ring chromosome 20 syndrome remain unknown. Here, we report two patients with ring chromosome 20 syndrome who had praxis‐induced reflex seizures.Case 1 was an 11‐year‐old girl who presented with seizures triggered by specific activities such as mental and written calculations, writing, decision‐making, recall, sudden changes in routine or ambient temperature and bathing. During calculations, left frontal lobe‐dominant, 3‐Hz slow‐wave bursts were observed on EEG. Lacosamide effectively suppressed her tonic seizures.Case 2 was a six‐year‐old boy who presented with seizures triggered by specific activities such as calculations, recall and bathing. During calculations, frontal lobe‐dominant, 3‐Hz spike and slow‐wave bursts were observed on EEG. Although his epilepsy was refractory, gabapentin reduced the frequency of focal seizures.In both cases, the hyperexcitability in the frontal lobe may have spread to the motor cortex and precipitated praxis‐induced seizures. Therefore, in addition to the known characteristic triad, praxis‐induced reflex seizures may also be a feature of ring chromosome 20 syndrome.
Transient epileptic amnesia diagnosed using long‐term electroencephalography
Authors: Jensen Camilla Dyremose , Kr⊘igård Thomas , Beier Christoph Patrick 
Published: October 2020

ABSTRACTTransient epileptic amnesia (TEA) is a distinct syndrome affecting middle‐aged persons without concurrent brain disease or disposition to epileptic seizures. Seizures are characterized by amnesia, usually lasting less than one hour, and interictal memory deficits that are common. Effective antiseizure treatment is usually rapid in patients with TEA, which underlines the need for prompt diagnosis. Here, we report a 58‐year‐old male patient with recurrent episodes of antero‐ and retrograde amnesia. MRI was normal and diagnosis was made using long‐term EEG (27 hours), revealing 10 right‐sided temporal lobe seizures with subtle clinical symptoms lasting up to 86 seconds. Details of the video‐EEG are presented. Treatment with levetiracetam resulted in complete recovery and seizure freedom that was confirmed on a second long‐term EEG. Given the favourable outcome with antiseizure treatment, our case study illustrates the role of long‐term EEG monitoring in patients with recurrent transient amnesia to establish a correct diagnosis [Published with video sequence].
МУЗЕЙ ИСТОРИИ ОБРАЗОВАТЕЛЬНОГО УЧРЕЖДЕНИЯ КАК ИНСТРУМЕНТ ФОРМИРОВАНИЯ ЭТНОКУЛЬТУРНОЙ И НАЦИОНАЛЬНОЙ ИДЕНТИЧНОСТИ СОВРЕМЕННОЙ МОЛОДЁЖИ
Authors: Левандина Ирина Алексеевна , Шалков Денис Юрьевич 
Published: October 2020

Цель исследования заключается в рассмотрении роли музея истории образовательного учреждения в патриотическом воспитании современной молодёжи, а также в формировании её этнокультурной и национальной идентичности.
Методология исследования базируется на принципах трансдисциплинарной социально-философской теории и методах культурологического анализа.
Результаты. В статье делается вывод о том, что подрастающее поколение с его тотальным погружением в мир виртуальной реальности зачастую отвергает традиционные, классические формы построения образовательного процесса в пользу интерактивных моделей усвоения компетенций и обмена информацией. В этих условиях музейные и историко-архитектурные комплексы, природные заповедники предоставляют уникальную возможность сохранить историческую память нации и освоить многовековой культурно-эстетический опыт. Авторы приходят к выводу о том, что важнейшим аспектом в воспитании молодёжи является музейная деятельность образовательных учреждений и развитие их сотрудничества с региональными музеями.
Перспективы использования результатов. Существует прямая связь между отношением студентов к учебному заведению, качеством профессиональной подготовки и усилением их патриотических настроений. Знание обучающимися истории образовательной организации способствует улучшению мотивации к учёбе и повышению качества успеваемости, формирует адекватную самооценку будущего специалиста и его активную гражданскую позицию.
ЛИЧНОСТНО-ОРИЕНТИРОВАННЫЕ ПРИНЦИПЫ И ТЕХНОЛОГИИ ФОРМИРОВАНИЯ ПРОФЕССИОНАЛЬНОЙ ИНФОРМАЦИОННОЙ КОМПЕТЕНТНОСТИ ОБУЧАЮЩИХСЯ ПО СПЕЦИАЛЬНОСТИ «СУДЕБНАЯ И ПРОКУРОРСКАЯ ДЕЯТЕЛЬНОСТЬ»
Authors: Шлыкова Нина Владимировна , Давыдова Галина  Ивановна 
Published: October 2020

Целью статьи является анализ личностно-ориентированных принципов и технологий формирования профессиональной информационной компетентности студентов в системе нормативных отношений, необходимых в практике профессиональной деятельности работников прокуратуры.
Методология исследования. Статья базируется на методологическом возвращении психологии к философским основаниям, что предполагает внеэмпирический путь познания — метапсихологию. На базе метапсихологии становится возможной интеграция психологии с социальными науками, изучение неявных аспектов психики опосредованно, через их проявление в культурогенезе.
Результаты. В статье рассматриваются личностно-ориентированные принципы и технологии как педагогические условия формирования профессиональной информационной компетентности в системе нормативных отношений, определяющих дальнейшую профессиональную деятельность будущих работников прокуратуры при обучении в специализированных (ведомственных) учебных заведениях.
Перспективы исследования. Результаты исследования могут быть использованы в процессе реформирования системы подготовки кадров для органов прокуратуры.
Medical Marijuana Effects in Movement Disorders, Focus on Huntington Disease; A Literature Review
Authors: Akinyemi Edward , Randhawa Gavin , Longoria Victor , Zeine Rana 
Published: October 2020

Purpose: We aimed to comprehensively evaluate the effects of medical marijuana on symptoms that are relevant to movement disorders with a focus on Huntington disease (HD). Methods: A systematic review by literature search through PubMed and EBSCO electronic databases was conducted for relevant studies reported after 2002 on the effects of medical marijuana or cannabis use on tremor, spasm, spasticity, chorea, sleep quality and HD-specific rating scales. Study selection, quality assessment and data extraction was performed by three reviewers. Outcome measures were changes in psychomotor, and sleep related symptoms. The methodological quality of the included studies was evaluated. Results: A total of 22 studies were reviewed. There was strong evidence for significant improvement in the neurologic symptoms of spasms, tremors, spasticity, chorea, and quality of sleep following treatment with medical marijuana. Analysis of specific motor symptoms revealed significant improvement after treatment in tremors and rigidity. Furthermore, all pretreatment and post-treatment measures indicated a significant increase in average number of hours slept. Conclusion: Larger scale studies are warranted to test the benefits of medical marijuana in HD patients. In the meanwhile, clinicians may consider prescribing medical marijuana as part of their strategy for better symptomatic treatment of patients with HD.
The Relationship Between Brain Tumor And Sleep Components (Psqi) In Siloam Hospitals Lippo Village 2015-2018
Authors: Uranus Hans Christian , July Julius 
Published: October 2020

<p><strong>Introduction</strong><strong>:</strong> Brain tumor can cause symptoms such as headache and seizure which might reduce sleep quality. Currently, sleep quality in brain tumor patients aren’t getting much attention. This study’s purpose is to determine the effect of brain tumor to sleep quality and its components in patients.</p><p><strong>Methods:</strong> The design of this study is a retrospective cohort, and it is done in Siloam Hospitals Lippo Village and Paviliun Umum Rumah Sakit Siloam from January-April 2019 with sample population consisting of brain tumor patients from age 19 until 59 years old. The sample amount is 29 subjects. PSQI is used to assess sleep quality and components. Data analysis uses the SPSS version 24.0 software and statistical analysis using chi<sup>2</sup>.</p><p><strong>Result:</strong> Brain tumor patients have worse sleep quality compared to the control, with 26 patients (89.7 %) having bad sleep quality. For the control, there are only 18 people (62.1%) who have bad sleep quality. The relationship between brain tumor and sleep quality have a p value of 0.032 and relative risk (RR) of 3,7. Brain tumor has a significant relationship with sleep latency (p value 0,015) and daytime dysfunction (p value 0,02)</p><p><strong>Conclusion:</strong> The relationship between brain tumor and sleep quality in brain tumor patients of Siloam Hospitals Lippo Village and Paviliun Umum Rumah Sakit Siloam, which was measured with the PSQI questionnaire is significant. Brain tumor also has a significant relation with sleep latency and daily dysfunction.</p>
Short-Term Memory Comparison Of Students Of Faculty Of Medicine Pelita Harapan University Batch 2015 Between The Handwriting And Typing Method
Authors: Widjaja Caroline , Sumali Stefanus Satria 
Published: October 2020

<p>Introduction : A lot of research has been done to determine if handwriting or typing note influenced short-term memory, however, the results obtained are still controversial. Therefore this study is structured to see the effect of note taking methods by handwriting and typing on short-term memory.</p><p>Aim : The aims of this study were to increase the performance of students in Faculty of Medicine Pelita Harapan University as well as providing the right and effective method of taking notes.<strong></strong></p><p>Method : Experimental study design was chosen in this study. Study population is students of faculty of medicine Pelita Harapan University batch 2015. 40 samples will be divide randomly into two, one group will take a note by handwriting and another by typing. Each group is required to watch a video about 15 minutes long. The results were analyzed statistically using T-test.</p><p>Result : The average of new information that can be remembered by group that take a note by handwriting significantly (p&lt;0,05) higher than group than take a note by typing with a p-value of 0,009.</p><p>Conclusion : Take a note by handwriting allows people to remember more new information than typing.</p>
The Relationship between AAS (Addiction Admission Scale) and APS (Addiction Potential Scale) with Timely Graduation of UPH Medical Faculty Students
Authors: Pardamean Engelberta , Sungono Veli 
Published: October 2020

<p><strong>Background:</strong> Addiction influential to neurotransmitter damage in the brain, resulting in physical fatigue and behavioral changes that will affect the length of studies of students. The MMPI-2 questionnaire is an instrument used to assess the Addiction Admission Scale / AAS and Addiction Potential Scale / APS.</p><p><strong> </strong></p><p><strong>Objective: </strong>This study looks at the relationship between AAS and APS with the timely graduation of students.</p><p> </p><p><strong>Methods:</strong> The study design of this research was cross-sectional for students of the Faculty of Medicine who were running a co-ass program at the Dharmawangsa Mental Hospital and had carried out the MMPI-2 test. Data analysis was done using Stata IC version 16 using t-test, spearman correlation test, and logistic regression.</p><p> </p><p><strong>Results: </strong>Of the 81 respondents, 67% of women and 33% of men and students who graduated on time amounted to 79%. T-test results obtained an AAS score in the group that was not on time (mean 2.53 ± 1.37) significantly higher than the group that was on time / study period of 5.5 years (mean 1.27 ± 1.56) with a p value of 0.0035. APS has a significant correlation to AAS with a coefficient value of r of 0.2595 and p value of 0.0201. AAS logistic regression test for the accuracy of graduation has a p value of 0.0067 with an OR value of 1.559 (95% CI 1.09-2.21).</p><p> </p><p><strong>Conclusion:</strong> There is a significant relationship between AAS on time graduation and there is no significant relationship between APS with on timely graduation.</p>
Effectiveness of Health Promotion Through Audiovisual Media and Lecture Methods on the Level of Knowledge in Elementary School Children About TB Disease
Authors: Trifitriana Monica , Fadilah Mariatul , Mulawarman Rido 
Published: October 2020

<p><strong>Introduction :</strong> Indonesia is the number two country for TB incidence in the world. To reduce the morbidity and death rate of tuberculosis cases, WHO issued an END-TB Strategy program that has 3 pillars. Pillar number 2 on the importance of cooperation with government, private stakeholders, and community for the prevention of TB disease, one of them in the form of health promotion. The application of speech methods and audiovisual media in conveying information has some differences in the process and achievement of students' level of understanding. This study aims to compare the effectiveness of the use lecture methods and audiovisual media in conveying information.</p><p><strong>Method :</strong> A total of 136 research subjects were 6th graders at Public Elementary School 205 Palembang and Private Elementary School YWKA Palembang divided into 2 groups for each elementary school. Each elementary school were subdivided into two groups, namely the audiovisual media group and the lecture method group. This study used quasi experimental design with nonequivalent pretest-posttest technique.</p><p><strong>Result :</strong> After the intervention, the level of understanding for the audiovisual media group was 87.90% while for the lecture method was 83.00% (effective when&gt; 75%) with a value of p &lt;0.05. Conclusion: the delivery of information on TB disease in grade 6 students assessed in two schools, both public and private, using audiovisual media and lecture methods were both equally effective, but the effectiveness of the audiovisual media was higher than the lecture method so that audiovisual media is considered better than lecture methods.</p>
UTILIZATION OF TELEHEALTH ON THE PATIENTS WITH POSTTRAUMATIC STRESS DISORDER (PTSD) [PENGGUNAAN TELEHEALTH PADA KLIEN DENGAN POSTTRAUMATIC STRESS DISORDER (PTSD)]
Authors: Hasibuan Shinta Yuliana , Hariyati Rr. Tutik Sri 
Published: October 2020

<p>The development of the industrial revolution 4.0 revolution affected various aspects of life also the environment. This is seen by the technological advances in the health sector, namely telehealth. Telehealth is one of the solutions in providing nursing care, one of which is patients with posttraumatic stress disorder (PTSD). Telehealth for patients with PTSD enables patients to be able to get treatment wherever and whenever the patient wants. The presence of telehealth will enable patients to reduce the symptoms of PTSD. Telehealth service systems use the internet with videoconferencing, eMental, telehealth video systems at home. With telehealth this also helps to erase the distance between communities, disabilities and elderly people living in rural areas, so they can get the right treatment. The writing of this scientific paper is expected to be able to describe the use of telehealth in patients with PTSD. This research method uses a literature review that focuses on the use of telehealth. The application of telehealth will have an impact on reducing the symptoms of PTSD. The results of this review literature found two of the five articles found containing a comparison between direct treatment and treatment via telehealth. Two studies on the application of telehealth at home and one article on the effectiveness of telehealth use in patients with PTSD.</p><p><strong>BAHASA INDONESIA </strong>Perkembangan revolusi industri 4.0 memengaruhi berbagai aspek kehidupan dan juga lingkungan sekitar. Hal ini dilihat dengan adanya kemajuan teknologi dalam bidang kesehatan yaitu telehealth. Telehealth merupakan solusi dalam memberikan asuhan keperawatan, salah satunya pasien dengan posttraumatic stress disorder (PTSD). Telehealth bagi pasien dengan PTSD memampukan pasien untuk dapat mendapatkan treatment dimanapun dan kapanpun pasien mau. Adanya telehealth akan memampukan pasien untuk menurunkan gejala dari PTSD. Sistem layanan telehealth menggunakan internet dengan system video conference, eMental, video telehealth di rumah. Dengan adanya telehealth hal ini juga membantu menghapuskan jarak antara masyarakat, disabilitas dan usia lanjut yang hidup di pedesaan sehingga mereka mampu mendapatkan treatment yang tepat. Penulisan karya ilmiah ini diharapkan dapat mendeskripsikan penggunaan telehealth pada pasien dengan PTSD. Metode penelitian ini menggunakan literature review yang berfokus pada penggunaan telehealth. Penerapan telehealth akan berdampak pada berkurangnya gejala-gejala dari PTSD. Hasil literature review ini menemukan dua artikel dari lima yang didapatkan berisi tentang perbandingan antara pemberian terapi secara langsung dan treatment melalui telehealth. Dua studi tentang penerapan telehealth di rumah dan satu artikel tentang keefektifan penggunaan telehealth pada pasien dengan PTSD.</p>
RADIO KOMUNITAS ANAK MUDA
Authors: Anggraeni Diana 
Published: October 2020

Tujuan penulisan artikel ini adalah untuk mendeskripsikan dan menjelaskan Radio Komunitas Dapur Remaja (RKDR) sebagai media informasi untuk mengembangkan potensi bagi kalangan anak muda di kawasan Cinangka, Sawangan Depok. Radio komunitas hingga saat ini masih dianggap menjadi media alternatif, untuk menjembatani minimnya informasi kepada masyarakat. radio komunitas disini menjadi sangat penting karena dianggap lebih mengetahui dan memahami persoalan dan isu-isu lokal di sekitarnya. Untuk menjawab rumusan masalah, riset ini menggunakan konsep radio komunitas dan pengembangan masyarakat,. Penelitian ini akan dilakukan dengan metode deskriptif kualitatif dengan melakukan observasi dan wawancara kepada pengelola Radio Komunitas. Hasil penelitian menyatakan bahwa Radio Komunitas Dapur Remaja (RKDR) telah menjalankan fungsinya sebagai media informasi bagi kepentingan warga komunitasnya. Namun informasi tersebut masih terbatas, dikarenakan program-program terkait pengembangan skill yang menjadi fokus pada usaha pengembangan potensi anak muda masih sangat minim. Minimnya kualitas SDM yang memahami persoalan anak muda juga menjadi kendala dalam menyiarkan informasi terkait materi pemberdayaan. Program siaran lebih banyak kepada pemutaran lagu-lagu dan informasi pembangunan yang bersifat umum sehingga tujuan komunitas belum berjalan secara maksimal.