bluuebunny/crossref_metadata_2025_split huggingface dataset:
Making Americans in the New York Public Library: Fantasy and Realities
Authors: Hochman Barbara 
Published: December 2024

Abstract
For marginalized readers in the United States, the public library has often been an icon of integration, assimilation, and self-making. At the New York Public Library (NYPL) of the 1920s, children’s librarians, mostly white and native born, assiduously drilled immigrant and African American children in acceptable modes of behavior and belief. To that end, they framed library protocols as indispensable American norms and selected highlights of US history as a proudly shared legacy. But a neglected Children’s Services archive shows that some librarians were at odds with this mission, and some children found it difficult to embrace either the behavioral norms or the history they were offered as their own. Contextualizing archival scraps and complementing them with other evidence, this article argues that NYPL Children’s Rooms were vibrant, frequently chaotic, physical spaces that presented challenges and opportunities for both children and librarians. Today, Children’s Rooms are more diverse and less authoritarian; they offer a more inclusive national history, but increasingly polarized visions of education threaten these gains. Tensions between the theory and practice of Americanization at NYPL in the 1920s disclose the complexity of belonging while anticipating ongoing debates about how to present the American past to twenty-first-century children.
TXNDC15, an ER-localized thioredoxin-like transmembrane protein, contributes to ciliary transition zone integrity
Authors: Yamazaki Shingo , Fujii Taiju , Chiba Shuhei , Shin Hye-Won , Nakayama Kazuhisa , Katoh Yohei 
Published: December 2024

ABSTRACT
Primary cilia have specific proteins on their membrane to fulfill their sensory functions. Preservation of the specific protein composition of cilia relies on the barrier function of the transition zone (TZ) located at the ciliary base. Defects in cilia and the TZ cause ciliopathies, which have diverse clinical manifestations, including Meckel syndrome (MKS). Many of the proteins mutated in individuals with MKS are known to constitute the MKS module of the TZ. Although TXNDC15 (also known as MKS14) is a thioredoxin-related transmembrane protein that is localized mainly in the endoplasmic reticulum (ER) and is mutated in individuals with MKS, its role at the TZ or within cilia has not been characterized. Here, we show that TXNDC15-knockout cells have defects in MKS module assembly and in ciliary membrane protein localization. These defects in TXNDC15-knockout cells were not rescued by exogenous expression of any of the TXNDC15 constructs with MKS variations in the thioredoxin domain. Furthermore, TXNDC15 with mutations of two cysteine residues within the thioredoxin domain failed to rescue defects in TXNDC15-knockout cells, suggesting that TXNDC15 controls the TZ integrity from outside the TZ via its thioredoxin domain.
Impacts of dietary fat on multi tissue gene expression in the desert-adapted cactus mouse
Authors: Blumstein Danielle M. , MacManes Matthew D. 
Published: December 2024

ABSTRACT
Understanding the relationship between dietary fat and physiological responses is crucial in species adapted to arid environments where water scarcity is common. In this study, we present a comprehensive exploration of gene expression across five tissues (kidney, liver, lung, gastrointestinal tract and hypothalamus) and 17 phenotypic measurements, investigating the effects of dietary fat in the desert-adapted cactus mouse (Peromyscus eremicus). We show impacts on immune function, circadian gene regulation and mitochondrial function for mice fed a lower-fat diet compared with mice fed a higher-fat diet. In arid environments with severe water scarcity, even subtle changes in organismal health and water balance can affect physical performance, potentially impacting survival and reproductive success. This study sheds light on the complex interplay between diet, physiological processes and environmental adaptation, providing valuable insights into the multifaceted impacts of dietary choices on organismal well-being and adaptation strategies in arid habitats.
Behavior and biomechanics: flapping frequency during tandem and solo flights of cliff swallows
Authors: Chizhikova Sophia , Mendez Laura X. , Hedrick Tyson L. 
Published: December 2024

ABSTRACT
Aerodynamic models of bird flight, assuming power minimization, predict a quadratic relationship (i.e. U-shaped curve) between flapping frequency and airspeed. This relationship is supported by experimental bird flight data from wind tunnels, but the degree to which it characterizes natural flight, and the extent to which birds might modify it to accommodate other behaviors, is less known. We hypothesized that the U-shaped relationship would vary or vanish when minimizing power is not a primary consideration. We analyzed videos of wild cliff swallows (Petrochelidon pyrrhonota) engaged in solo and tandem (i.e. following or being followed by a conspecific) flights to collect bird flapping frequencies and airspeeds. Solo birds had a U-shaped flapping frequency to speed relationship. Birds engaged in tandem flights had the opposite pattern; their flapping frequencies varied with speed as an inverse U-shaped curve and were up to 2.1 times higher than solo birds at the same speed.
An innovative multicomponent compression system in a single bandage for venous leg ulcer and/or oedema treatment: a real-life study in 343 patients
Authors: Dissemond Joachim , Schicker Christoph , Breitfeld Tino , Keuthage Winfried , Häuser Elisa , Möller Udo , Thomassin Laetitia , Stücker Markus 
Published: December 2024

Objective: This study aimed to evaluate the performance of an innovative multicomponent compression system in a single bandage (UrgoK1, Laboratoires Urgo, France) in the treatment of patients with venous leg ulcers (VLUs) and/or lower limb oedema in everyday practice. Method: A prospective, observational, clinical study with the evaluated compression system was conducted in 39 centres in Germany between March 2022 and July 2023. Main outcomes included a description of the treated patients, changes in wound healing and oedema progression, local tolerance and acceptability of the compression system. Results: In total, 343 patients were treated with the evaluated compression system for a mean period of 48±30 days; 196 had a VLU and 275 had oedema, mostly of venous origin. By the final visit, 49% of VLUs healed (75% in absence of oedema and 61% in VLUs of ≤1 month's duration). Oedema was completely resolved or greatly improved in 87% of patients, with significant reduction in calf and ankle circumferences. Improvement in pruritus, pain, age-related ankle mobility and skin changes were also reported in patients who experienced them at baseline. The system was judged ‘very easy’ to apply (median: 108 seconds, three times a week), ‘extremely useful’ and ‘very well accepted’ by most patients who reported an improvement in comfort compared with previous systems. Similar results were observed when patients and/or their relatives were involved in the bandage application between the study visits. During the study, three cases of local intolerance related to the system and five early terminations (unrelated to the system) were reported. Conclusion: These results are consistent with the previous clinical evidence available on this new compression system and further support its good efficacy, tolerability, acceptability and usefulness in the treatment of patients with VLUs and/or oedema.
CodedEvents: Optimal Point-Spread-Function Engineering for 3D-Tracking With Event Cameras
Authors: Metzler Chris , Shah Sachin , Chan Matthew , Cai Haoming , Chen Jingxi , Kulshrestha Sakshum , Singh Chahat Deep , Aloimonos Yiannis 
Published: December 2024

This talk explores the fundamental limits of 3D tracking with PSF engineering and event cameras. We demonstrate existing phase masks are already near-optimal for localizing flashing point sources, but suboptimal for tracking moving objects.
Full-text article not available; see video presentation
Chip-Scale Atomic Devices: From Clocks to Brain Imaging and Beyond
Authors: Kitching John 
Published: December 2024

Chip-scale atomic clocks and sensors combine elements of precision atomic spectroscopy, silicon micromachining and photonics technology to achieve good performance with small size and low power consumption. Recent advances will be discussed including compact optical clocks, micromachined atomic beam clocks.
Full-text article not available; see video presentation
Plasmonic Platforms for SERS Sensing
Authors: Pastoriza-Santos Isabel 
Published: December 2024

This seminar will provide an overview of the latest results of the FunNanoBio Group in the Nanoplasmonic field with special emphasis on the fabrication of plasmonic nanostructures for (bio)sensing based on surface-enhanced Raman scattering
Full-text article not available; see video presentation
Application of an Open-Path Broadband Source-Based Mobile Instrumentation for Greenhouse Gas Monitoring
Authors: Cristescu Simona , Krebbers Roderik , van Kempen Kees , Khodabakhsh Amir 
Published: December 2024

Open-path spectroscopy using broadband coherent light sources can provide highly sensitive multispecies detection capability for various real-life applications. Using these systems, we present our recent results for monitoring gas emissions from a wastewater treatment plant.
Full-text article not available; see video presentation
Morbidity associated with schistosomiasis in adult population of Chókwè district, Mozambique
Authors: Serra João Tiago , Silva Carina , Sidat Mohsin , Belo Silvana , Ferreira Pedro , Ferracini Natália , Kaminstein Daniel , Thompson Ricardo , Conceiçao Claúdia 
Published: December 2024

Background
Mozambique is one of the countries with the highest prevalence of schistosomiasis, although there is little data on the prevalence of disease and associated morbidity in the adult population. This study aimed to describe and characterize the morbidity associated with schistosomiasis in the adult population of Chókwè district and to explore the use of anamnestic questionnaires and urine dipsticks, as well as point-of-care ultrasound for urinary related findings, to better characterize disease prevalence and morbidity.

Methodology
Between April and October 2018, we conducted a cross-sectional study embedded within the Chókwè Health Research and Training Centre. Data were collected on sociodemographic variables, signs and symptoms for schistosomiasis and water related activities. Infection status was determined by urine filtration, Kato-Katz thick smear and DNA detection. Point-of care urinary tract ultrasonography was performed to assess structural morbidity associated with Schistosoma haematobium infection. Multivariate logistic regression was used to search for associations between risk factors, signs and symptoms, infection status and ultrasound abnormalities.

Principal findings
Our study included 1033 participants with a median age of 34 years old. The prevalence of Schistosoma haematobium, Schistosoma mansoni and ultrasound detected urinary tract abnormalities were 11.3% (95% CI 9.5%-13.4%), 5.7% (95% CI 4.3%-7.5%) and 37.9% (95% CI 34.8%-41.2%), respectively. Of the 37.9% with urinary tract abnormalities, 14.5% were positive for Schistosoma haematobium. Reported hematuria in the last month (p = 0.004, aOR 4.385) and blood in the urine dipstick (p = 0.004, aOR 3.958) were markers of Schistosoma haematobium infection. Reporting lower abdominal pain (p = 0.017, aOR 1.599) was associated with ultrasound abnormalities.

Conclusion
Using microscopy and DNA analysis for both Schistosoma haematobium and Schistosoma mansoni in conjunction with urinary ultrasound abnormalities gives us several insights into correlations between disease prevalence (microscopic and anatomical) and demographic details in a high-risk population.
Enhancing lobaplatin sensitivity in lung adenocarcinoma through inhibiting LDHA-targeted metabolic pathways
Authors: Yuan Siyu , Ou Wenjie , Mi Xuguang , Hou Junjie 
Published: December 2024

Background and objective
Lung adenocarcinoma (LUAD), a subtype of non-small cell lung cancer (NSCLC), is associated with high incidence and mortality rates. Effective treatment options are limited due to the frequent development of multidrug resistance, making it crucial to identify new therapeutic targets and sensitizing agents. This study investigates the role of Lactate dehydrogenase A (LDHA) in enhancing the chemotherapy sensitivity of Lobaplatin (LBP) in LUAD.

Methods
Bioinformatics analyses were performed using data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) to assess LDHA expression in LUAD tissues. LUAD cell lines A549 and NCL-H1975 were treated with siRNA targeting LDHA and the small molecule inhibitor Oxamate. We measured changes in lactate production, ATP levels, NAD+ and pyruvate levels, and assessed cell viability. The chemotherapy sensitivity to Lobaplatin was evaluated, and key signaling pathways related to chemotherapy resistance were analyzed.

Results
The inhibition of LDHA resulted in a significant reduction in lactate production and ATP levels, along with an increase in NAD+ and pyruvate levels. These metabolic alterations led to decreased cell viability and enhanced sensitivity to Lobaplatin. The study identified the PI3K/AKT signaling pathway as a critical mediator of this enhanced sensitivity, with reduced phosphorylation of AKT observed upon LDHA inhibition. Furthermore, the combination of LDHA inhibition and Lobaplatin treatment demonstrated a synergistic effect, significantly inhibiting tumor growth and highlighting the potential of LDHA as a therapeutic target to overcome drug resistance in LUAD.

Conclusion
Targeting LDHA and disrupting lactate metabolism and its signaling pathways can effectively enhance the sensitivity of LUAD to Lobaplatin, providing a promising approach to overcoming multidrug resistance. These findings offer valuable insights into developing new treatment strategies for lung adenocarcinoma, emphasizing the role of metabolic pathways in cancer therapy.
The relationship between lifecourse traumatic events and pain in an older rural South African population: A cross-sectional study
Authors: Wang Ting Ting , Payne Collin , Mall Sumaya , Tollman Stephen , Harling Guy 
Published: December 2024

Background
Pain in older adults is an increasing concern in low- and middle-income countries (LMICs), with literature suggesting an association with past traumatic events (TEs) in high-income settings. We aim to investigate this relationship in a population-representative sample of older adults with high burden of TEs in a rural South African community.

Methods
The Health and Aging in Africa: A longitudinal Study of an INDEPTH Community in South Africa (HAALSI) study collected data pain intensity, using the Brief Pain Inventory, and TEs with a 16-item questionnaire, from 2411 participants aged 40–79 in 2014–15. We used logistic regression models to test the association between TE exposure and self-reported pain status.

Results
TE experience was near-universal (99.1% experience of at least one), while 9.0% of participants reported current pain, of which 86.6% was moderate/severe. In multivariable regression, increased odds of moderate/severe pain was associated with more TEs of any kind (OR 1.08; 95%CI 1.02–1.15 per additional TE) and with past exposure to disasters, accidents and illnesses (men and women), violence in the community (women only) and social/family environment problems (men only)–but not with childhood or war-related TEs.

Conclusions
TEs were associated with pain even within a rural resource-limited setting where trauma experiences were extremely common. However, associations varied by TE type and sex. Interventions to prevent pain in older adults need to be targeted to block specific mechanisms that vary within even at-risk populations.
Estimation of foveal avascular zone area from a B-scan OCT image using machine learning algorithms
Authors: Toyama Taku , Maruko Ichiro , Zhou Han Peng , Ikeda Miki , Hasegawa Taiji , Iida Tomohiro , Aihara Makoto , Ueta Takashi 
Published: December 2024

Purpose
The objective of this study is to estimate the area of the Foveal Avascular Zone (FAZ) from B-scan OCT images using machine learning algorithms.

Methods
We developed machine learning models to predict the FAZ area from OCT B-scan images of eyes without retinal vascular diseases. The study involved three models: Model 1 predicted the FAZ length from B-scan images; Model 2 estimated the FAZ area from the predicted length using 1, 3, or 5 horizontal measurements; and Model 3 converted the FAZ area from pixels to mm2. The models’ performance was evaluated using Mean Absolute Error (MAE), Mean Squared Error (MSE), and the Coefficient of Determination (R2). The FAZ area was subsequently estimated by sequentially applying Models 1→2→3 on a new dataset.

Results
Model 1 achieved a MAE of 2.86, MSE of 17.56, and R2 of 0.87. Model 2’s performance improved with the number of horizontal measurements, with the best results obtained using 5 lines (MAE: 40.36, MSE: 3129.65, R2: 0.95). Model 3 achieved a MAE of 1.52e-3, MSE of 4.0e-6, and R2 of 1.0. The accuracy of FAZ area estimation increased with the number of B-scan images used, with the correlation coefficient rising from 0.475 (1 line) to 0.596 (5 lines). Bland–Altman analysis showed improved agreement between predicted and actual FAZ areas with increasing B-scan images, evidenced by decreasing biases and narrower limits of agreement.

Conclusions
This study successfully developed machine learning models capable of predicting FAZ area from OCT B-scan images. These findings demonstrate the potential for using OCT images to predict OCTA data, particularly in populations where OCTA imaging is challenging, such as children and the elderly. Future studies could explore the developmental mechanisms of the FAZ and macula, providing new insights into retinal health across different age groups.
A systematic literature review of attitudes, intentions and behaviours of teaching academics pertaining to AI and generative AI (GenAI) in higher education: An analysis of GenAI adoption using the UTAUT framework
Authors: Nikolic Sasha , Wentworth Isabelle , Sheridan Lynn , Moss Simon , Duursma Elisabeth , Jones Rachel A , Ros Montserrat , Middleton Rebekkah 
Published: December 2024

The rapid advancement of artificial intelligence (AI) has outpaced existing research and regulatory frameworks in higher education, leading to varied institutional responses. Although some educators and institutions have embraced AI and generative AI (GenAI), other individuals remain cautious. This systematic literature review explored teaching academics' attitudes, perceptions and intentions towards AI and GenAI, identifying perceived benefits and obstacles. Utilising the unified theory of acceptance and use of technology framework, this study reveals positive attitudes towards AI's efficiency and teaching enhancement, but also significant concerns about academic integrity, accuracy, reliability, skill development and the need for comprehensive training and policies. These findings underscore the necessity for institutional support to navigate the integration of AI and GenAI in tertiary education.

Implications for practice or policy:

Attitudes towards AI and GenAI integration are diverse with educators recognising benefits but raising ethical and practical concerns. These concerns indicate a need for a more comprehensive understanding and dialogue within academic communities.
Academics' intentions to use these technologies are contingent upon the development of robust ethical guidelines and supportive institutional policies.
Institutional support and training shape behaviours. The scarcity of formal training, systematic guidelines and policy frameworks currently limits effective integration.
Wyzwania i perspektywy geografii społeczno- ekonomicznej i gospodarki przestrzennej
Authors: Czasopisma Redakcja 
Published: December 2024

Punktem zwrotnym w rozwoju geografii w Polsce było wydzielenie w 2018 r. geografii społeczno-ekonomicznej i gospodarki przestrzennej jako dyscypliny naukowej w dziedzinie nauk społecznych, z jednoczesnym przyporządkowaniem geografii fizycznej do dyscypliny nauki o Ziemi i środowisku w dziedzinie nauk ścisłych i przyrodniczych. Stworzyło to szanse, ale i zagrożenia, zarówno dla nowej dyscypliny, jak i dyscyplin pokrewnych. Kwestie takie, jak integralność geografii społeczno-ekonomicznej i gospodarki przestrzennej, jej miejsce w naukach społecznych, relacje z innymi dyscyplinami społecznymi, zakres integracji z geografią fizyczną i skutki tego procesu dla rozwoju całej geografii czy wreszcie instytucjonalne aspekty funkcjonowania nowej dyscypliny, to najważniejsze problemy, wobec których stanęła nowa dyscyplina.
Electrorheological characterization of complex fluids used in electrohydrodynamic processes: Technical issues and challenges
Authors: Rijo Pedro C. , Galindo-Rosales Francisco J. 
Published: December 2024

Abstract
The electrorheological (ER) characterization of low-viscosity fluids is paramount for producing micro- and nanoscale products through electrohydrodynamic (EHD) techniques, such as EHD-jet printing, electrospray, and electrospinning. Key properties such as viscosity, surface tension, dielectric properties, electrical conductivity, and relaxation time significantly influence both the quality and properties of the final products and the efficiency of the industrial process. ER characterization is essential for studying the macroscopic effects of the interaction between these physicochemical properties under controlled flow kinematics. Researchers may face several technical challenges in performing rigorous ER characterization of moderate conductive fluids typically used in EHD processes. This characterization is crucial for formulating inks compatible with these processes and for understanding fluid dynamics in EHD processes to ensure stable printing conditions and achieve high-resolution, accurate prints. This work highlights the inherent limitations of current ER cells and proposes methodologies to mitigate their impact on measurement accuracy. Furthermore, we propose the use of microfluidic devices as a solution for the ER characterization of moderate conductive fluids.
Chemical ethics practices in HEBUST of China
Authors: Liu Xinwei , Wu Tong , Sun Yujuan , Gu Limin , Wen Jingjing , Liu Shaohui , Yang Kun , Sun Fengxia 
Published: December 2024

Abstract
Hebei University of Science and Technology (HEBUST) actively carries out chemical ethics education practices and incorporates chemical ethics modules into the curriculum, aiming to improve students’ morality, responsibility, knowledge and skills. In the teaching of basic courses, relevant content of chemical ethics is introduced to guide students to think about the ethics of chemical. At the same time, the university has built a diversified practical platform and organized students to participate in laboratory research projects. HEBUST invites enterprise engineers to give lectures and carry out “practical month” activities. The design homework of senior students also incorporates ethical considerations to cultivate students’ ability to practice ethical principles in actual engineering. In addition, the school also invited retired experts from the Organisation for the Prohibition of Chemical Weapons (OPCW) to give lectures. The relevant majors have passed the Washington Accord certification and the certification of the China Engineering Education Professional Certification Association. External supervision has promoted the continuous deepening of the reform of chemical ethics education. Therefore, HEBUST has provided an effective example for cultivating chemically and engineering-talented people with social responsibility and also provided a reference for other colleges and universities to carry out chemical ethics education.