bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of Saccharomyces cerevisiae on the Inhibition of Heat‐Induced Toxicants in French Fries
Authors: Verma Vandana , Singh Zoomi , Yadav Neelam 
Published: December 2024

ABSTRACTAcrylamide (AA) and 5‐hydroxymethylfurfural (HMF) are the byproducts of the Maillard reaction that pose health risks due to their high exposure to the Western diet. Current study examines the impact of yeast fermentation on AA, HMF formation, and chemical composition of French fries. Fermentation, known for enriching food with beneficial probiotics, vitamins, and minerals, is coupled with blanching, a technique used to inactivate enzymes and reduce microbial load, thus preserving color and extending shelf life. Fermentation reduced HMF and AA levels in French fries by approximately 86.5% and 54.78%, respectively. Furthermore, combining fermentation with blanching treatment further decreased HMF and AA levels by 88.62% and 59.81%, respectively. This research suggests that yeast fermentation, particularly when combined with blanching treatment, can effectively mitigate the formation of AA and HMF in French fries, thereby potentially reducing their health risks. This pioneering research opens avenues for additional inquiries, laying the groundwork for future advancements in enhancing food safety.
Relating preservice teacher's bilingual teaching self‐efficacy to lesson differentiation practices for multilingual learners
Authors: Hernández Ana M. , Daoud Annette 
Published: December 2024

AbstractThis study examined bilingual preservice teachers' self‐efficacy in the context of lesson differentiation for multilingual learners in Spanish. Thirty‐six bilingual preservice teachers across three California State University programs participated in a quantitative methods study of lesson plan analysis. Findings showed that preservice teachers were not sufficiently skilled at differentiating instruction for learners with distinct linguistic needs and assets. Results indicated that, although preservice teachers had high levels of English learner (EL) teaching self‐efficacy towards multilingual learners, there was low correlation with their ability to provide lesson differentiation. The study concluded that differentiation is a complex process that requires extensive knowledge of content standards, understanding students' linguistic assets, and enacting purposeful high‐leverage strategies with supports and scaffolds to meet multilingual learners' needs.
Redefining inclusive teacher education: All students means all students
Authors: Andrei Elena , Jackson Debbie K. , Banks Tachelle 
Published: December 2024

AbstractTraditionally, in U.S. K‐12 schools, inclusive education has been used in the context of students with disabilities participating in the general content area or the mainstream classroom together with their peers. We redefine inclusive education (and subsequently inclusive teacher education) to refer to teaching all students, including multilingual learners. We argue, based on our conceptualization and practice, that training inclusive teachers requires 1) a carefully planned curriculum; 2) instructors who are inclusive educators themselves and know from experience and training the mainstream classroom, special education and/or English as a second language (ESL); and 3) collaboration with schools and districts.
Teachable moments in support of K‐12 social and emotional learning in the TESOL Practicum
Authors: Thomas M'Balia , Rosenberg Allie 
Published: December 2024

AbstractGlobally, K–12 schools are embracing practices of social and emotional learning (SEL) to address students' interactional and emotional needs and to create a safe and nurturing environment for their learning. As a curricular program and approach to pedagogy, SEL instruction socializes learners into specific social and cultural ways of naming, claiming, expressing, evaluating, and valuing emotions and emotional states in oneself and others. To inquire into the language skills, behaviors, and ideologies drawn upon during SEL instruction, a collaborative self‐study of teaching and teacher education practice was undertaken as part of a preservice teacher's TESOL practicum placement. Situated in a third‐grade classroom at an English as a second language (ESL) cluster site school located in the U.S. Midwest, the self‐study examines rich points (Agar, 1999) that surface within the practicum student's teaching demonstration of SEL skills delivered during a morning meeting. Through critical reflection, reframing and transformation of practice, and collaborative engagement in self‐study research with the practicum student's supervisor, this work demonstrates how inquiry into instructional rich points can evolve into teachable moments that educators can draw upon in support of classroom students' development of not only SEL skills and competencies, but also grade‐level curricular knowledge and English language development. The inquiry also reveals the social, cultural, and linguistic socialization that underlies SEL instruction and its impact on classroom learners, student teachers, and even teacher educators.
Selection of best randomized controlled trials of Japanese Kampo medicines: Introduction of the trials and the hardships in their conduction
Authors: Motoo Yoshiharu , Tominaga Kazunari , Suzuki Hidekazu , Kaido Toshimi , Matsuda Chu , Morita Satoshi , Kogure Toshiaki , Arai Ichiro , Tsutani Kiichiro 
Published: December 2024

AbstractBackgroundMore than 500 randomized controlled trials (RCTs) were selected from various databases by the evidence‐based medicine committee of the Japan Society for Oriental Medicine (JSOM). Their structured abstracts have been published in Japanese and English in “Evidence Reports of Kampo Treatment.”MethodsFrom among these RCTs, “Kampo Best RCTs” were selected according to impact factor and number of Google Scholar citations.ResultsFour of the authors in this article presented their data at a symposium at the 74th Congress of the JSOM in June 2024. Kazunari Tominaga was elected as the No. 1 author among the best RCTs. His two articles described the effects of rikkunshito on functional dyspepsia and non‐erosive gastroesophageal reflux disease, respectively. Hidekazu Suzuki was elected as No. 2. His article described the effect of rikkunshito on functional dyspepsia. The No. 3 author, Toshimi Kaido, and No. 4 author, Chu Matsuda, described the effects of daikenchuto on adult gastrointestinal disorder following liver transplant and the effects of hangeshashinto on chemotherapy‐induced stomatitis, respectively. These four articles were all based on double‐blind RCTs. Although a range of hardships were encountered during the studies, these RCTs were reported in original articles, providing clinical evidence of high international reputation.ConclusionHere, we describe the details and the hardships encountered by the authors, identify points to note in the interpretation of clinical trial results, and finally mention the current status and future prospects of Kampo RCTs.
An ongoing concern: 20 years of research on equine atypical myopathy
Authors: François Anne‐Christine , Renaud Benoît , Kruse Caroline‐Julia , Marcillaud‐Pitel Christel , Votion Dominique‐Marie 
Published: December 2024

AbstractAnne‐Christine François, Benoît Renaud, Caroline‐Julia Kruse, Christel Marcillaud‐Pitel and Dominique‐Marie Votion of the Atypical Myopathy Alert Group discuss insights from 20 years of research and surveillance on equine atypical myopathy.
DC reactive sputtering synthesis of titanium nitride coatings on titanium for biomedical applications
Authors: Nguyen Duy Cuong , Phuong Pham Thi Mai , Tran Van Dang , Duc Dang Minh , Van Thiet Duong , Pham Vuong‐Hung 
Published: December 2024

AbstractIn this study, the titanium nitride (TiN) films were deposited on Ti substrates using DC reactive sputtering. The structure and morphology of the TiN films were analyzed by X‐ray diffraction, scanning electron microscopy, energy dispersive X‐ray spectroscopy, X‐ray photoelectron spectrometry and Auger electron spectroscopy. In vitro biocompatibility of the TiN films was evaluated using scanning electron microscopy and a confocal electron scanning microscope. The results show that TiN films have been successfully formed, hardness and in vitro biocompatibility have been improved compared to that of Ti substrates.
A facile and cost‐effective method for crystalline cellulose extraction from sugarcane bagasse applied to remove crystal violet dye from solution
Authors: Phong Le Vinh , Tien Ho Dang , Vo Khuong Quoc 
Published: December 2024

AbstractIn this work, crystalline cellulose (CC) was extracted from sugarcane bagasse through a facile modification method and further applied to absorb crystal violet dye (CV) in aqueous media. The proposed modification approach uses a mixture of NaOH and H2O2 only in a two‐step extraction process. This method is more straightforward than previous extraction methods, which used complex mixtures of solvents and additives. The yield obtained was 76.90%, approximately higher than several works declared before. The as‐prepared product was then determined with Fourier transform infrared spectroscopy (FT‐IR) and X‐ray diffraction (XRD) to analyze the presence of the functional groups and crystallinity, respectively. Furthermore, surface morphology, specific surface area of 0.634 m2 g−1, pore diameters of 3.010 nm, and pore size distribution of the obtained CC were determined with scanning electron microscope (SEM) and Brunauer–Emmett–Teller (BET) methods from the nitrogen adsorption–desorption isotherm, respectively. Additionally, serial experiments were conducted to investigate the influence of pH on the CV removal process. The results showed that the extracted material had a wide operating pH range of 6.0–9.0 and exhibited the highest CV treatment ability at pH 7.0. Besides, the effect of the parameters on the CV removal abilities, such as contact time (1–90 min), adsorbent dose (0.01–0.5 g), and initial CV concentration (10–100 mg L−1), was also investigated. To evaluate the CV removal ability of extract CC in the aqueous media and propose a suitable adsorption mechanism, we used several adsorption isotherms and adsorption kinetic models, such as Langmuir, Freundlich, Temkin, and Elovich. The obtained results showed that the adsorbent followed the pseudo‐second‐order kinetic model. Moreover, according to the Langmuir adsorption isotherm model, the maximum CV adsorption capacity (qm) of the CC was 8.857 mg g−1. Thermodynamic parameters such as −20 < ΔG0 < 0 (kJ mol−1), ΔH0 was 29.500 kJ mol−1, and the positive ΔS0 proved that the CV adsorption process of the CC was physical adsorption, spontaneous and endothermic. Overall, this study offers a simple approach based on the acid hydrolysis method for the high‐value utilization of sugarcane bagasse to isolate CC. This obtained product could become an active adsorbent for removing CV from the aqueous solutions.
Analyzing the physical chemistry of the structural dynamics and stabilizing interactions of citrazinic acid‐ammonium formamide complex
Authors: Sunny Sneha Anna , Hrangkhawl Nathan , Jayakumar Devadath , Babu Anijith , Begum N. Fazulunnisa , Thomas Renjith 
Published: December 2024

AbstractThis paper studies the nature of the non‐covalent interactions in the complex formed by citrazinic acid and ammonium formamide (CA‐AF), employing the principles of density functional theory (DFT). The individual molecules of CA and AF, as well as their combined dimer CA‐AF, underwent optimization in a gas‐phase environment, utilizing the M062X/aug‐cc‐pVDZ approach. The study calculated the binding energy for the optimized dimer to evaluate its thermodynamic stability. To qualitatively dissect the nature of interactions within the CA‐AF complex, techniques such as the reduced density gradient (RDG) method and quantum theory of atoms in molecules (QTAIM) were applied. Charge distribution across the complex's atoms was scrutinized through Mulliken population analysis and natural population analysis. The study also explored the electronic characteristics of the complex, with a focus on charge delocalization, which was analyzed using natural bond orbital techniques. The investigation unveiled a notable hydrogen bond interaction between CA's hydrogen and AF's oxygen atoms, a finding corroborated by QTAIM analysis. This exploration enhances the understanding of non‐covalent bonding in complex molecular structures, offering valuable insights into molecular interaction dynamics.
The Controversy over Expert Consensus in Science
Authors: Jorm Anthony 
Published: December 2024

AbstractThis chapter defines “expert consensus in science” as a high level of agreement among scientists with relevant expertise about a specific scientific claim, methodology or science-based practice or policy. In the not-too-distant past, the topic of expert consensus in science would only have been of interest to scientists and scholars in the history, philosophy and sociology of science. However, there is now a much broader interest in the topic from both scientists and non-scientists alike. A major reason for this is that expert consensus is increasingly used to guide national policies based on scientific findings, but some of these policies may be at odds with people’s pre-existing beliefs and values, and they understand little about scientific consensus. Examples are the role of human activity in global warming, the use of genetically modified crops and the safety of vaccination of infants. The chapter surveys the range of sceptical opinion about the legitimate role of consensus in science. The book challenges the sceptical view, arguing that expert consensus plays a vital role in scientific processes. However, these processes could be improved, and the book proposes how this could be done.
Consensus Pervades Scientific Processes
Authors: Jorm Anthony 
Published: December 2024

AbstractThis chapter argues that, contrary to the views of the consensus sceptics, consensus processes pervade science. Using examples from a range of scientific areas, it shows how consensus is involved in generating ideas and setting priorities, assessing funding applications and distributing access to resources, selecting methods to use in a research project, publication of scientific findings, reviewing the published literature and drawing conclusions on facts. Taking a specific example of a research project, it identifies ten points during the research where consensus processes were involved.
Methods for Determining Deliberative Consensus
Authors: Jorm Anthony 
Published: December 2024

AbstractThis chapter describes the range of methods that have been used for determining deliberative consensus. These are Delphi studies, the nominal group technique, surveys of experts, systematic analysis of conclusions in the peer-reviewed literature, consensus conferences and expert working groups. There are also emerging methods which are not yet in common use: scientific citation networks, prediction markets and artificial intelligence.
A dynamical Einstein-Born-Infeld-dilaton model and holographic quarkonium melting in a magnetic field
Authors: Jena Siddhi Swarupa , Barman Jyotirmoy , Toniato Bruno , Dudal David , Mahapatra Subhash 
Published: December 2024

Abstract
We generalize the potential reconstruction method to set up a dynamical Einstein-Born-Infeld-dilaton model, which we then use to study holographic quarkonium melting in an external magnetic field. The non-linear nature of the model allows to couple the magnetic field to the quarkonium inner structure without having to introduce back-reacting charged flavour degrees of freedom. The magnetic field dependent melting temperature is computed from the spectral functions and suggests a switch from inverse magnetic to magnetic catalysis when the magnetic field increases. We also discuss the differences due to the anisotropy brought in by the external field.
Synthesis, characterization, and evaluation of KDM4B inhibitors to attenuate inflammatory host immune response in periodontitis
Authors: Garrabrant Kathleen A. , Furbish Amelia B. , Turner Jonathan M. , Gomez Ivett Pina , Mills Catherine M. , Maddi Abhiram , Peterson Yuri K. 
Published: December 2024

AbstractPeriodontal disease begins with bacterial plaque buildup in the oral cavity, inciting an inflammatory response that results in subsequent tissue damage. Even after standard treatment like scaling and root planning (SRP) to remove plaque and biofilm, the host immune response can remain hyper-active, perpetuating further tissue destruction. In these cases, aggressive periodontitis is resistant to SRP and the inflammatory response may persist, even in the absence of plaque, presenting a significant clinical challenge. Previous experiments have provided a validated model of periodontal inflammation by exposing murine macrophages to lipopolysaccharide (LPS) from Aggregatibacter actinomycetemcomitans (Aa), a pathogen linked to aggressive periodontitis. Using this model, we have previously demonstrated that the periodontal disease microenvironment triggers epigenetic changes, notably heightened lysine-specific demethylase 4B (KDM4B) activity. Data indicate that the KDM4B inhibitor ML324 can reverse the macrophage-mediated pro-inflammatory response induced by Aa LPS in vitro, providing compelling evidence for KDM4B as a rational therapeutic target for periodontal disease. In the present studies, a cohort of compounds was developed as potential KDM4B inhibitors. Synthesis and characterization of derivatives led to the discovery of compound 14 with an IC50 of 170 nM against KDM4B and immunosuppressive activity in the Aa LPS challenge model. These results suggest KDM4B inhibitors as potential therapeutic agents for modulating the immune response for periodontal disease.
Characteristics of autoantibody-positive individuals without high-risk HLA-DR4-DQ8 or HLA-DR3-DQ2 haplotypes
Authors: Redondo Maria J. , Cuthbertson David , Steck Andrea K. , Herold Kevan C. , Oram Richard , Atkinson Mark , Brusko Todd M. , Parikh Hemang M. , Krischer Jeffrey P. , Onengut-Gumuscu Suna , Rich Stephen S. , Sosenko Jay M. ,   the Type 1 Diabetes TrialNet Study Group
Published: December 2024

Abstract

Aims/hypothesis
Many studies of type 1 diabetes pathogenesis focus on individuals with high-risk HLA haplotypes. We tested the hypothesis that, among islet autoantibody-positive individuals, lacking HLA-DRB1*04-DQA1*03-DQB1*0302 (HLA-DR4-DQ8) and/or HLA-DRB1*0301-DQA1*0501-DQB1*0201 (HLA-DR3-DQ2) is associated with phenotypic differences, compared with those who have these high-risk HLA haplotypes.

Methods
We classified autoantibody-positive relatives of individuals with type 1 diabetes into four groups based on having both HLA-DR4-DQ8 and HLA-DR3-DQ2 (DR3/DR4; n=1263), HLA-DR4-DQ8 but not HLA-DR3-DQ2 (DR4/non-DR3; n=2340), HLA-DR3-DQ2 but not HLA-DR4-DQ8 (DR3/non-DR4; n=1607) and neither HLA-DR3-DQ2 nor HLA-DR4-DQ8 (DRX/DRX; n=1294). Group comparisons included demographics, metabolic markers and the prevalence of autoantibodies against GAD65 (GADA%), IA-2 (IA-2A%) or insulin (IAA%) at enrolment. A p value <0.01 was considered statistically significant.

Results
IA-2A% was lower in the DRX/DRX group (20.9%) than in the DR4/non-DR3 (38.5%, p<0.001) and DR3/DR4 (44.8%, p<0.001) groups, but similar to the DR3/non-DR4 group (20.0%). Conversely, IAA% was similar in the DRX/DRX (43.4%), DR4/non-DR3 (41.1%) and DR3/DR4 (41.0%) groups, but lower in the DR3/non-DR4 group (30.1%, p<0.001). Participants in the DRX/DRX group were older, with a lower prevalence of White participants and a higher prevalence of overweight/obesity, and higher preserved C-peptide (as measured by a lower Index60) than those in the DR3/DR4 group (all comparisons, p<0.005), a lower prevalence of White or non-Hispanic participants and a lower Index60 than those in the DR4/non-DR3 group, and younger age, a higher prevalence of Hispanic participants and a lower Index60 than those in the DR3/non-DR4 group (all comparisons, p<0.005). Among the 1292 participants who progressed to clinical type 1 diabetes, those in the DR3/non-DR4 group had higher GADA%, lower IA-2A% and lower IAA% than the other groups (all comparisons, p<0.01), and those in the DR3/DR4 group had the youngest age at diagnosis (all comparisons, p<0.001).

Conclusions/interpretation
Autoantibody-positive individuals who lack both high-risk HLA haplotypes (DRX/DRX) or have HLA-DR3-DQ2 but lack HLA-DR4-DQ8 (DR3/non-DR4) have phenotypic differences compared with DR3/DR4 and DR4/non-DR3 individuals, suggesting that there is aetiological heterogeneity in type 1 diabetes.

Graphical Abstract
Coefficient of friction in the demoulding forces of the injection moulding process—a review
Authors: Rodrigues Ângela R. , Correia Mário S. , Pontes António J. 
Published: December 2024

AbstractEjection is the most critical phase in the injection moulding process and depends on several variables that can affect and difficult the demoulding process. Some phenomena in the mould, such as shrinkage, adhesion and friction, can lead to higher ejection forces. Friction, deformation and adhesion mechanisms are components of the coefficient of friction that occurs between the mould and the part surface. An increase in the coefficient of friction will result in higher ejection forces and consequently increase the energy consumption during the demoulding process. Mould and part material, mould surface roughness, coatings and ejection temperature are some of the variables that can affect the coefficient of friction in the injection moulding process. This review paper presents some considerations on the mechanisms, the process and material variables that can affect the coefficient of friction.
Optimizing control parameters for Huanglongbing disease in citrus orchards using SAIR-SI compartmental model, epidemic final size, and genetic algorithms
Authors: Anzo Hernández Andrés , Giménez Mujica Uvencio José , Hernández Gracidas Carlos Arturo , Oliveros Oliveros José Jacobo 
Published: December 2024

Abstract
Huanglongbing (HLB) is a bacterial disease that affects citrus trees worldwide. We present an innovative approach for identifying optimal control and risk measures for HLB in citrus orchards. Our method is based on a mathematical model that incorporates the number of roguing trees and a logistic growth model for the dynamic of the Asian Citrus Psyllid (ACP), the primary vector for HLB transmission. We derive an expression for: (1) the basic reproduction number

$$R_{0}$$

R
0

; (2) the final size for the number of roguing trees; and (3) the transmission risk. The above let us propose a difference map equation that assesses this final size with a low computational cost. We use this difference map in an evolutionary algorithm to identify the most effective combination of control parameter values for reducing HLB transmission, including the timing and frequency of roguing and the use of insecticides. In this sense, we propose two control strategies, which we called tree-centered and vector-centered.