bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of compositing with snail meat powder on protein nutritional quality of sorghum–wheat buns using a rat bioassay
Authors: Agengo Fredrick B , Onyango Arnold N , Serrem Charlotte A , Okoth Judith 
Published: February 2020

AbstractBACKGROUNDProtein energy malnutrition (PEM) is an important health burden in most developing countries mainly in sub‐Saharan Africa, where it contributes to high rates of child morbidity and mortality. This study evaluated the efficacy of compositing with snail meat powder (SMP) on protein nutritional quality of sorghum–wheat buns using a rat bioassay. Nine diets –seven isonitrogenous diets, based on six variations of buns and a reference diet made using skimmed milk powder, in addition to the basal diet meant to estimate the endogenous nitrogen excretion and a 16% protein rehabilitation diet – were fed to male weanling albino rats. Protein efficiency ratio (PER), and food efficiency ratio (FER), net protein retention ratio (NPRR), apparent protein digestibility (APD), and true protein digestibility (TPD), protein digestibility corrected amino acid score (PDCAAS), and digestible indispensable amino acid score (DIAAS) indices of protein quality were determined.RESULTSFortification with SMP significantly (P < 0.05) enhanced PER from 0.21% to 2.70%, FER from 0.02% to 0.27%, APD from 81.17% to 88.28%, and TPD from 87.48% to 95.38%. PDCAAS and DIAAS increased from 45% to 78% and 44% to 69% respectively in unfortified buns to buns fortified with 25% SMP.CONCLUSIONComplementary diets fortified with SMP promote growth and rehabilitate emaciated rats, whereas unfortified diet did not support weight gain. Thus, supplementation of buns with SMP might enhance a faster recovery in children affected by PEM. © 2020 Society of Chemical Industry
Assembly and application advancement of organic‐functionalized graphene‐based materials: A review
Authors: Jiang Xiangqiong , Ruan Guihua , Huang Yipeng , Chen Zhengyi , Yuan Huamei , Du Fuyou 
Published: February 2020

AbstractOwing to the remarkable physicochemical properties such as hydrophobicity, conductivity, elasticity, and light weight, graphene‐based materials have emerged as one of the most appealing carbon allotropes in materials science and chemical engineering. Unfortunately, pristine graphene materials lack functional groups for further modification, severely hindering their practical applications. To render graphene materials with special characters for different applications, graphene oxide or reduced graphene oxide has been functionalized with different organic agents and assembled together, via covalent binding and various noncovalent forces such as π–π interaction, electrostatic interaction, and hydrogen bonding. In this review, we briefly discuss the state‐of‐the‐art synthetic strategies and properties of organic‐functionalized graphene‐based materials, and then, present the prospective applications of organic‐functionalized graphene‐based materials in sample preparation.
Can Ultrasonography Be Useful in Planning Surgery for De Quervain Tenosynovitis?: A Prospective Study With Emphasis on Detection of the Superficial Radial Nerve and Dominant Pathologic Tendon
Authors: Kim Sung‐Jae , Lee Chang‐Hun , Khil Eun Kyung , Choi Jung‐Ah , Im Woo‐Young , Lee Kwang‐Hyun 
Published: February 2020

ObjectivesWe performed preoperative ultrasonography (US) to detect the anatomic course of the superficial radial nerve (SRN) and dominant pathologic tendon of the first extensor compartment in de Quervain tenosynovitis.MethodsWe prospectively studied 27 patients (29 wrists) with de Quervain tenosynovitis who underwent surgical release of the first extensor compartment. Preoperatively, US was performed to evaluate the presence of the dominant pathologic tendon and the septum in the subcompartment, number of SRNs in the area of the surgical incision, and anatomic running course of the SRN. These variables were also checked intraoperatively. Cohen κ statistics were calculated to investigate agreement between US and surgical field findings.ResultsThere were 7 men and 20 women (mean age, 47.8 years; range, 26–67 years). For the dominant pathologic tendon, there were 2 cases (6.9%) of an abductor pollicis longus, 11 cases (37.9%) of an extensor pollicis brevis, and 16 cases (55.2 %) of a nondominant tendon (κ = 0.94). For the subcompartment, there were 10 cases (34.5%) without a septum, 8 (27.6%) with an incomplete septum, and 11 (37.9%) with a complete septum (κ = 0.95). Most SRNs crossed over the first extensor compartment (κ = 0.78).ConclusionsPreoperative US can be useful in detecting the anatomic running course of the SRN and dominant pathologic tendon before surgery for de Quervain tenosynovitis. Classifying the anatomic course of the SRN could be essential to planning surgery, and it could be helpful to prevent injury of the SRN during surgery.
Alternation of the Mode Synchronization and Desynchronization in Ultrafast Fiber Laser
Authors: Du Yueqing , Sergeyev Sergey V. , Xu Zuowei , Han Mengmeng , Shu Xuewen , Turitsyn Sergei K. 
Published: February 2020

AbstractUltrafast fiber lasers offer a unique opportunity to implement optically a Poincaré mapping in the phase space of a variety of complex dissipative dynamical systems operating far from the equilibrium. Understanding of such complex optical dynamical systems revealing, for instance, ultrafast dynamics of the dissipative solitons (DSs) and more complex regimes is important for advancing specification and performance of the mode‐locked lasers used in a vast number of applications ranging from spectroscopy and medicine to metrology and telecom. Here, using the mode‐locked fiber laser as a test‐bed, the Shilnikov‐type ultrafast dynamics taking the form of randomly switching between noise‐like pulsing and quasi‐continuous‐wave regimes is experimentally demonstrated. The transient coherence recovery is revealed, during which the noise‐like pulse (NLP) is transformed into a coherent DS state and then returned to an incoherent NLP state. The demonstrated alternation of mode synchronization and desynchronization is both of practical importance for developing new types of partially mode‐locked lasers and of the fundamental interest for the nonlinear science in the context of revealing routes to the turbulence in distributed nonlinear systems.
Modulation of Living Cell Behavior with Ultra‐Low Fouling Polymer Brush Interfaces
Authors: Víšová Ivana , Smolková Barbora , Uzhytchak Mariia , Vrabcová Markéta , Zhigunova Yulia , Houska Milan , Surman František , de los Santos Pereira Andres , Lunov Oleg , Dejneka Alexandr , Vaisocherová‐Lísalová Hana 
Published: February 2020

AbstractUltra‐low fouling and functionalizable coatings represent emerging surface platforms for various analytical and biomedical applications such as those involving examination of cellular interactions in their native environments. Ultra‐low fouling surface platforms as advanced interfaces enabling modulation of behavior of living cells via tuning surface physicochemical properties are presented and studied. The state‐of‐art ultra‐low fouling surface‐grafted polymer brushes of zwitterionic poly(carboxybetaine acrylamide), nonionic poly(N‐(2‐hydroxypropyl)methacrylamide), and random copolymers of carboxybetaine methacrylamide (CBMAA) and HPMAA [p(CBMAA‐co‐HPMAA)] with tunable molar contents of CBMAA and HPMAA are employed. Using a model Huh7 cell line, a systematic study of surface wettability, swelling, and charge effects on the cell growth, shape, and cytoskeleton distribution is performed. This study reveals that ultra‐low fouling interfaces with a high content of zwitterionic moieties (>65 mol%) modulate cell behavior in a distinctly different way compared to coatings with a high content of nonionic HPMAA. These differences are attributed mostly to the surface hydration capabilities. The results demonstrate a high potential of carboxybetaine‐rich ultra‐low fouling surfaces with high hydration capabilities and minimum background signal interferences to create next‐generation bioresponsive interfaces for advanced studies of living objects.
Inter‐Individual Variation in Cancer and Cardiometabolic Health Outcomes in Response to Coffee Consumption: A Critical Review
Authors: Visser Edith , Geleijnse Johanna M. , de Roos Baukje 
Published: February 2020

ScopeCoffee is associated with a lower risk of cancer, cardiovascular disease, and type 2 diabetes at the population level. However, individual susceptibility to the effects of coffee consumption will cause heterogeneity in health responses between individuals. In this critical review determinants of inter‐individual variability in cancer and cardiometabolic health outcomes in response to coffee and caffeine consumption are systematically evaluated.Methods and resultsEmbase and MEDLINE are searched for observational studies and clinical trials that examined variation in the response to coffee consumption. A total of 74 studies meet the inclusion criteria, which report variation in cancer (n = 24) and cardiometabolic health (n = 50) outcomes. The qualitative analysis shows that sex, BMI, smoking, alcohol intake, menopausal status, and genetic polymorphisms are probable or possible determinants of inter‐individual variability in cancer and cardiometabolic health outcomes in response to coffee and caffeine consumption, albeit the majority of studies have insufficient statistical power to detect significant interaction between these factors and coffee consumption.ConclusionSeveral genetic and non‐genetic determinants of inter‐individual variability in the responses to coffee and caffeine consumption are identified, indicating that some of the health benefits of coffee may only occur in a subgroup of subjects.
Slot antenna miniaturization by loading dumbbell‐shaped slots and strips, square‐shaped loops, and shorting vias
Authors: Karmokar Debabrata K. , Chen Shu‐Lin 
Published: February 2020

AbstractA technique to miniaturize the size of a slot antenna is presented. Square‐shaped loops, dumbbell‐shaped slots, and strips together with small circular patches and shorting vias are loaded on the two ends of the main radiating slot for the antenna miniaturization. A step‐by‐step analysis of miniaturizing the antenna is provided. It is shown here that the antenna can be miniaturized, that is, the resonance frequency is lowered, by over 56% using this technique. This antenna is realized into a prototype, and the size reduction is verified experimentally.
Do drug‐related safety warnings have the expected impact on drug therapy? A systematic review
Authors: Georgi Ulrike , Lämmel Julia , Datzmann Thomas , Schmitt Jochen , Deckert Stefanie 
Published: February 2020

AbstractPurposeThe need for drug‐related safety warnings is undisputed, and their impact should also be evaluated. This systematic review investigates and assesses the impact of safety warnings on drug therapy.MethodsStudies published in English between January 1998 and December 2018 were searched in EMBASE and MEDLINE, complemented by manual search. Randomised controlled trials, cohort studies with a before/after component, and case‐control studies were included, selected to predefined criteria, and assessed for their reporting and methodological quality.ResultsOut of 7454 references identified, 72 studies were included. A total of 28/72 (39%) studies described the impact of safety warnings on drug therapy as being effective, whereas 12/72 (17%) studies did not. Further, 26/72 (36%) studies described a partial implementation of the warnings (one part of the warning had an impact on drug therapy and another did not). Unintended effects were investigated in 6/72 (8%) studies.While 34 (47%) studies examined safety warnings on psychotropic drugs using an interrupted time series (ITS) design (53%), a before/after (26%), and a time series design (21%), 38 (53%) studied other substances using an ITS design (34%), a before/after (40%), and a time series design (26%). The proportion of an effective impact on drug therapy was lower in the “psychotropic drugs” group (23%) than in the “others” group (53%).ConclusionDrug‐related safety warnings induce intended and unintended effects. The included studies are of broadly varying methodological quality. To better compare their effectiveness, studies should be conducted using standardised procedures.
Cover Image, Volume 69, Issue 3
Authors: Endo Takeshi , Sudo Atsushi 
Published: February 2020

The cover image is based on the Mini‐Review Well‐defined, environment‐friendly synthesis of polypeptides based on phosgene‐free transformation of amino acids into urethane derivatives and their applications by Takeshi Endo et al., https://doi.org/10.1002/pi.5952.Cover image © Takeshi Endo Images.
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Registration of ‘S14‐15146GT’ soybean, a high‐yielding RR1 cultivar with high oil content and broad disease resistance and adaptation
Authors: Chen Pengyin , Shannon Grover , Scaboo Andrew , Crisel Melissa , Smothers Scotty , Clubb Michael , Selves Stewart , Vieira Caio Canella , Ali Md. Liakat , Mitchum Melissa Goellner , Nguyen Henry , Li Zenglu , Bond Jason , Meinhardt Clinton , Klepadlo Mariola , Li Shuxian , Mengistu Alemu , Robbins Robert T. 
Published: February 2020

AbstractS14‐15146GT (Reg. no. CV‐534, PI 691841) is a late‐maturity group IV (relative maturity 4.6) indeterminate glyphosate‐tolerant soybean [Glycine max (L.) Merr.] cultivar developed and released by the University of Missouri Fisher Delta Research Center Soybean Breeding program. High global demand for soybean oil and US southern growers’ preference for taller soybean plants with early maturity led to the release of this cultivar. S14‐15146GT was evaluated in 130 environments across 10 states and showed high yield potential and wide adaptation in Missouri and other southern states. It is resistant to Phytophthora root rot, stem canker, sudden death syndrome, frogeye leaf spot, and charcoal rot. S14‐15146GT has white flowers, tawny pubescence, and tan pod walls. Seeds of S14‐15146GT have black hilum, yellow cotyledon, and intermediate luster. S14‐15146 GT seed averages 235.5 and 390.8 g kg−1 oil and protein content, respectively. The early maturity with the first‐generation Roundup Ready trait, high yield potential, high oil content, broad disease resistance package, and wide adaptation make S14‐15146GT an excellent choice for southern growers.
Front Cover
Authors: Wei Peng , Demaeght Peter , De Schutter Kristof , Grigoraki Linda , Labropoulou Vassiliki , Riga Maria , Vontas John , Nauen Ralf , Dermauw Wannes , Van Leeuwen Thomas 
Published: February 2020

The front cover image is based on the Research Article Overexpression of an alternative allele of carboxyl/choline esterase 4 (CCE04) of Tetranychus urticae is associated with high levels of resistance to the keto‐enol acaricide spirodiclofen by Peng Wei et al., https://doi.org/10.1002/ps.5627.
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Dissipative control for nonlinear Markovian jump systems with mixed time‐delays: The discrete‐time case
Authors: Ma Lifeng , Fang Xiaoli , Yuan Yuan , Zhang Jie , Bo Yuming 
Published: February 2020

SummaryThis article is concerned with the dissipative control problem for discrete‐time nonlinear Markovian jump systems subject to both discrete and distributed time‐delays. The purpose is to design a state feedback controller that is capable of guaranteeing the required closed‐loop stability and dissipativity performances simultaneously. By resorting to Lyapunov functional methodology and completing square technique, sufficient conditions are established for the existence of the desired state feedback controller in terms of certain Hamilton‐Jacobi inequalities (HJIs). Within the provided framework, the required controller parameters can be obtained by solving the corresponding HJIs. Finally, two numerical simulation examples are presented to demonstrate the correctness and effectiveness of the developed control paradigm.
Enhanced hydrologic simulation may not improve downscaled soil moisture patterns without improved soil characterization
Authors: Pauly Matthew J. , Niemann Jeffrey D. , Scalia Joseph , Green Timothy R. , Erskine Robert H. , Jones Andrew S. , Grazaitis Peter J. 
Published: February 2020

AbstractFine‐resolution soil moisture maps (10–30 m grid cells) are useful for many applications, including agricultural production and off‐road vehicle mobility. Fine‐resolution maps of soil moisture can be produced by downscaling coarse‐resolution soil moisture data from remote sensing. Soil moisture downscaling has been conducted by modeling key hydrologic processes in the soil, but current downscaling methods neglect two key aspects of soil hydrology: surface runoff and residual water content. The objective of this study is to understand how these hydrologic considerations affect spatial patterns of soil moisture and whether their inclusion improves downscaling performance. The Equilibrium Moisture from Topography, Vegetation, and Soil (EMT+VS) downscaling model is used to address these questions. Surface runoff is introduced to the model by implementing an infiltration capacity based on the saturated hydraulic conductivity. Residual water content is included by assuming that all hydrologic processes cease when soil moisture is at or below the residual water content. The pre‐existing EMT+VS model is compared with the new models using data from northeastern Colorado. The results show that both model additions introduce more complex dependence on the spatial variability of soil texture, which is difficult to estimate accurately. Including surface runoff provides only a small improvement in model performance, and residual water content shows almost no effect on the performance in this case. Thus, the simplifying assumptions of the pre‐existing model provide an appropriate level of complexity, given the uncertainties of the spatial input data.
Strategies to Construct a Chemical‐Fuel‐Driven Self‐Assembly
Authors: Wang Guangtong , Liu Shaoqin 
Published: February 2020

AbstractFuel‐driven self‐assembly widely exists in the biological world since functional micro‐ or nanostructures in living bodies are usually transiently formed by biomolecular self‐assembly far from thermodynamic equilibrium driven by active molecules (chemical fuel), for example, adenosine triphosphate (ATP). Therefore, research focusing on artificial fuel‐driven self‐assembly has drawn extensive attention in recent years. Compared with spontaneous molecular self‐assembly at thermodynamic equilibrium, constructing a fuel‐driven self‐assembly remains complicated because it requires a delicately designed chemical reaction network mainly involving an “activation” and a “deactivation”. In this Minireview, we will review recent developments in fuel‐driven self‐assembly and generalize several strategies for constructing such a self‐assembly. Besides that, the functional micro‐ or nanostructures and materials achieved by these fuel‐driven self‐assemblies will also be discussed.
Management of pediatric blunt abdominal trauma in a Dutch level one trauma center
Authors: Spijkerman Roy , Bulthuis Lauren C. M. , Hesselink Lillian , Nijdam Thomas M. P. , Leenen Luke P. H. , de Bruin Ivar G. J. M. 
Published: February 2020

Abstract
Purpose
Most children with intra-abdominal injuries can be managed non-operatively. However, in Europe, there are many different healthcare systems for the treatment of pediatric trauma patients. Therefore, the aim of this study was to describe the management strategies and outcomes of all pediatric patients with blunt intra-abdominal injuries in our unique dedicated pediatric trauma center with a pediatric trauma surgeon.

Methods
We performed a retrospective, single-center, cohort study to investigate the management of pediatric patients with blunt abdominal trauma. From the National Trauma Registration database, we retrospectively identified pediatric (≤ 18 years) patients with blunt abdominal injuries admitted to the UMCU from January 2012 till January 2018.

Results
A total of 121 pediatric patients were included in the study. The median [interquartile range (IQR)] age of patients was 12 (8–16) years, and the median ISS was 16 (9–25). High-grade liver injuries were found in 12 patients. Three patients had a pancreas injury grade V. Furthermore, 2 (1.6%) patients had urethra injuries and 10 (8.2%) hollow viscus injuries were found. Eighteen (14.9%) patients required a laparotomy and 4 (3.3%) patients underwent angiographic embolization. In 6 (5.0%) patients, complications were found and in 4 (3.3%) children intervention was needed for their complication. No mortality was seen in patients treated non-operatively. One patient died in the operative management group.

Conclusions
In conclusion, it is safe to treat most children with blunt abdominal injuries non-operatively if monitoring is adequate. These decisions should be made by the clinicians operating on these children, who should be an integral part of the entire group of treating physicians. Surgical interventions are only needed in case of hemodynamic instability or specific injuries such as bowel perforation.
Nächtliche Verkehrslärmbelästigung in Deutschland: individuelle und regionale Unterschiede in der NAKO Gesundheitsstudie
Authors: Wolf Kathrin , Kraus Ute , Dzolan Mihovil , Bolte Gabriele , Lakes Tobia , Schikowski Tamara , Greiser Karin Halina , Kuß Oliver , Ahrens Wolfgang , Bamberg Fabian , Becher Heiko , Berger Klaus , Brenner Hermann , Castell Stefanie , Damms-Machado Antje , Fischer Beate , Franzke Claus-Werner , Gastell Sylvia , Günther Kathrin , Holleczek Bernd , Jaeschke Lina , Kaaks Rudolf , Keil Thomas , Kemmling Yvonne , Krist Lilian , Legath Nicole , Leitzmann Michael , Lieb Wolfgang , Loeffler Markus , Meinke-Franze Claudia , Michels Karin B. , Mikolajczyk Rafael , Moebus Susanne , Mueller Ulrich , Obi Nadia , Pischon Tobias , Rathmann Wolfgang , Schipf Sabine , Schmidt Börge , Schulze Matthias , Thiele Inke , Thierry Sigrid , Waniek Sabina , Wigmann Claudia , Wirkner Kerstin , Zschocke Johannes , Peters Annette , Schneider Alexandra 
Published: February 2020

Zusammenfassung
Hintergrund
Lärmbelästigung geht mit gesundheitlicher Beeinträchtigung und reduziertem Wohlbefinden einher. Die subjektive Lärmbelästigung steht im Zusammenhang mit der objektiven Lärmbelastung sowie individuellen und regionalen Faktoren.

Fragestellung
Wie viele Teilnehmende der NAKO Gesundheitsstudie fühlen sich durch nächtlichen Verkehrslärm belästigt und welche Faktoren stehen damit im Zusammenhang?

Material und Methoden
Diese Querschnittsanalyse basiert auf Daten von 86.080 NAKO-Teilnehmenden aus 18 Studienzentren, die von 2014 bis 2017 untersucht wurden. Um die Beziehungen zwischen individuellen und regionalen Faktoren und Verkehrslärmbelästigung in den Kategorien nicht belästigt, leicht/mittel und stark/sehr stark belästigt zu untersuchen, wurden multinomiale logistische Regressionsmodelle mit wechselseitiger Adjustierung der Faktoren verwendet.

Ergebnisse
Zwei Drittel der Teilnehmenden fühlten sich nicht durch Verkehrslärm belästigt; jeder Zehnte berichtete von starker/sehr starker Belästigung, mit den höchsten Anteilen in Berlin-Mitte und Leipzig. Die stärksten Assoziationen mit Lärmbelästigung wurden für Faktoren der individuellen Wohnsituation beobachtet, wie z. B. die Position des Schlafraums zur Hauptstraße (OR für leicht/mittel belästigt: 4,26 [95 % KI: 4,01; 4,52]; OR für stark/sehr stark belästigt: 13,36 [95 % KI: 12,47; 14,32] im Vergleich zu Garten/Innenhof). Teilnehmende im Alter von 40–60 Jahren oder der mittleren und niedrigen Einkommensklasse fühlten sich eher durch Verkehrslärm belästigt als jüngere bzw. ältere Teilnehmende oder solche mit hoher Einkommensklasse.

Diskussion
Teilnehmende der NAKO Gesundheitsstudie wiesen Unterschiede in der Belästigung durch nächtlichen Verkehrslärm in Bezug auf individuelle und regionale Faktoren auf.