bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge and practices among caregivers in cases of persisitent diarrhoea in children of age group 6 months-12 years
Authors: Mandavi Swetleena , Shrivastava Varsha , Jamod Yamini 
Published: October 2019

Background: Persistent diarrhoea has a variety of infectious and non-infectious etiology and it seriously affects the growth and development of children. The objective of the is to the identify the knowledge and practices prevalent amongst caregivers of children to understand environmental and behavioral risk factors and their interactions associated with the disease and its management.Methods: It is a hospital based cross-sectional study which included 70 children in the age group 6 months-12 years admitted in a tertiary care center at Bhopal over a period of one year with complaints of loose stools lasting for more than 14 days. A pre-tested questionnaire was used as a data collection tool for face-to-face interviews with the mothers or caretakers of the cases. Statistical analysis was done using Statistical Package of Social Science (SPSS Version 20; Chicago Inc., USA). Data comparison was done by applying specific statistical tests to find out the statistical significance of the comparisons.Results: Most of children’s mother were Illiterate, 27.1% were educated till primary school and only 5.7% were graduate. Out of 70 cases, most of 51(72.8%) were have understanding that drinking untreated water is a risk factor, only 11(15.7%) understands the value of filtered water and 8(11.4%) know the importance of doing boiling. Most of 46(65.7%) were using open field for sanitation and only 11(15.7%) were using toilets at home. 42(60.0%) were having the habit of hand washing before taking meal. Conclusions: Community education about the prevention and management of diarrhoea will reduce the mortality and morbidity associated with persistent diarrhoea.
Study on impact of protein energy malnutrition on development in children
Authors: Patel Dhara , Issac Greeshma 
Published: October 2019

Background: Majority of the children in India who live below the poverty line in an environment of deprivation and starvation have physical and developmental retardation. The Objective of this study to study the impact and comparison of protein energy malnutrition on the development with normal children.Methods: This was a hospital based cross sectional study in which total 128 cases of protein energy malnutrition and 30 normal children were enrolled from nutritional rehabilitation center and in patients wards. The study population comprised of children less than 5 years of age, having weight for height/length ≤3 SD, with visible wasting, or bipedal oedema, with mid arm circumference <11.5 cm were assessed for their development in all four domains using Denver II developmental Screening Test (DDST-II).Results: The gross motor milestones are affected in 62.5% with grade4 PEM & 42.85% with grade 3, the fine motor component is affected more in grade 4 with other domains less affected, no significant relation of language delay with PEM was observed in this study, 40% of children with grade 4 PEM shows delay in social domain while 18.18% of the patients with grade 3 PEM show delay in social domain. No patients with grade 1 or grade 2 PEM showed delay in social domain. All four domains are affected in PEM with a maximum effect in gross motor, but the difference does not seem to be significant as the p value is 0.3 i.e. >0.05 which is insignificant.Conclusions: My study on the effect of protein energy malnutrition on development proves that there in increasing delay in all the domains of development with increasing grade of malnutrition. Early detection of malnutrition in community can cause early intervention and increase the productivity of nation.
Evaluate the role of endoscopy and ultrasonography in patients of portal hypertension
Authors: Das Ghanshyam , Gautam Shweta , Pal Vijay 
Published: October 2019

Background: Aim of the study was to evaluate the role of endoscopy and ultrasonography in pediatric patients suffering from portal hypertension .subjects: children under 12 years of age hospitalized with any symptom or sign suggestive of portal hypertension.Methods: The study was conducted in 30 children with portal hypertension. They were divided into two groups on the basis of site of lesion: extrahepatic (extra hepatic portal vein obstruction) and intrahepatic (chronic liver diseases).Results: Mean age of children with EHPVO (extra hepatic portal vein obstruction) was 4 years and 4 months while that of children with CLD (chronic liver diseases) mean age was 8 years and 4 months. Endoscopic findings in patients with EHPVO have severe grade of varices as compared to those with CLD. In patients with EHPVO, the most common USG finding was nonvisualisation of the main portal vein or either branch (75-85%). Portal vein cavernoma was seen in 75% of these patients. Portosystemic collaterals were visualized in 23 patients in which the left gastric collateral (60%) was the most common followed by short gastric collaterals in 11 children (55%).Conclusions: Endoscopy and ultrasonography are new and better modalities to assess the diagnosis and severity of portal hypertension. Extra hepatic portal vein obstruction is the commonest cause followed by intrahepatic obstruction (Chronic liver diseases).
A rare and interesting case of Scarabiasis
Authors: Varghese Sangeetha Merrin , J. Austoria A. , Koshy Manju , Abraham Jithin Mathew 
Published: October 2019

Scarabiasis or Canthariasis or Beetle disease is an ectoparasitic infection of the gastrointestinal tract, in which the beetles temporarily infest the digestive tract and rarely the urinary tract. Dung beetle belongs to Scarabiaediae family. It is mostly seen in children aged between 2 to 5 years, who play outdoor for prolonged hours without undergarments. It is a temporary infestation in which early stages of development of beetle takes place in the anus and the adult beetle flies, out of the anus while defecation. A boy aged 3 years and four months presented to the pediatric OPD with complaints of peri umbilical abdominal pain, vomiting, nausea, mucus in stool along with “black insects” in his stool. The clinical examination revealed that the pulse rate, blood pressure and temperature were normal. Per rectal examination and ultrasound of the abdomen was normal. Routine examination of stool and urine was also found to be normal. The beetle was identified by the medical entomologist as dung beetle belonging to family Scarabidae. This report implies that the boy had an infestation with the larvae of dung beetle in the gastro intestine. The family belonged to the high range area of Mundakayam. Agriculture is the main source of income for people and main plantation being Rubber. Natives breed cattle for their livelihood and agriculture. During contact with mud or while playing outdoors naked, he would have come into contact with the eggs or the beetle, which hatched into larvae and caused canthariasis.
The resurgence of Measles in 2019
Authors: P. V. Chaitanya Varma , Rajkumar Samitha 
Published: October 2019

Measles, a highly contagious infection caused by a single stranded RNA Paromyovirus is transmitted through aerosol droplets and contact with nasopharyngeal secretions of the infected patient. The incubation period lasts between 10 and 14 days. The Prodromal phase presents with high grade fever, cough, coryza and conjunctivitis. Punctate blue-white spots on the buccal mucosa called Koplik spots are pathognomic of measles. The typical maculopapular rash appears 3-5 days after the onset of fever. It starts from the neck and spreads down to the lower limbs; it decreases in the same pattern lasting for 5-6 days. The patients are considered contagious 4 days prior to 4 days after the appearance of rash.
Assessment of physical and dissolution characteristics of various itraconazole capsule formulations: a comparative analysis
Authors: Verma Rajan , Hodge Shrikant , Gargote Chandrashekhar , Modi Prakash , Upreti Naresh , Yadav Lokesh , Pillai Raviraj 
Published: October 2019

<p class="abstract"><strong>Background:</strong> This <em>in vitro</em> study compared physical parameters and the dissolution profile of innovator itraconazole capsule formulation, i-Tyza, and 5 other generic capsule formulations available in the Indian market.</p><p class="abstract"><strong>Methods:</strong> The number of pellets and size distribution were determined using naked eye examination and sieving method, respectively. Dissolution profile of formulations was done at 15, 30, 45, and 60 minutes, using a United States Pharmacopeia type II Paddle apparatus in simulated gastric fluid (SGF, pH 1.2) without enzymes, acetate buffer (pH 4.5) with 0.5% sodium lauryl sulfate (SLS), and phosphate buffer (pH 6.8) with 0.5% SLS.<strong></strong></p><p class="abstract"><strong>Results:</strong> All formulations had capsule size 0. Capsule fill weight (~335 to ~510 mg) and total pellet number (127 to 810) varied across formulation, with the innovator brand having the highest number of pellets. Innovator product and i-Tyza had similar fill weight (~460 mg). Pellet size distribution of the innovator product, brand 2, brand 3, and i-Tyza was relatively narrow. In SGF, except brand 1 (84% dissolved) and brand 5 (80% dissolved), all the formulations had near-complete (&gt;85% drug dissolved) or complete dissolution (&gt;90% drug dissolved) at 60 minutes. In acetate buffer, pH 4.5 with 0.5% SLS and phosphate buffer, pH 6.8 with 0.5% SLS, only the innovator product and i-Tyza demonstrated near-complete to complete dissolution at 60 minutes (96% and 90% dissolved).</p><p class="abstract"><strong>Conclusions:</strong> Across all the itraconazole generic formulations evaluated, i-Tyza had comparable physical characteristics and dissolution profile to the innovator product. The <em>in vitro</em> dissolution profile of i-Tyza may indicate adequate <em>in vivo</em> performance.</p>
A study on cutaneous adverse drug reactions in a tertiary care center in Rajnandgaon, Chattisgarh
Authors: Pandey Pooja , Pandey Prabhat , Manore Sharad , Sandesara Darshan 
Published: October 2019

<p class="abstract"><strong>Background:</strong> Cutaneous reactions are one of the most common types of adverse drug reactions which may vary from mildly discomforting to those that are life-threatening.</p><p class="abstract"><strong>Methods:</strong> This prospective, observational study was done in the department of dermatology. Patients with suspected drug rash, of either sex or all age groups were included in the study.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 114 patients were enrolled in the study. The most common presenting symptoms of cutaneous adverse drug reactions (CADRs) were itching, burning sensation and pigmentation with 61.31%, 13.87% and 10.22% respectively. A total of 21 different CADRs were observed. The common causative agents were of anti-microbial, nervous system and musculoskeletal class in both outdoor and indoor patients with 51 (37.22%), 21 (15.32%) and 25 (18.24%) respectively.</p><p class="abstract"><strong>Conclusions:</strong> The most common CADR observed in the study was antimicrobials and NSAIDs were the most common causative drugs.</p><p class="abstract"> </p>
Treatment outcome of acne vulgaris with topical application of clindamycin gel and benzoyl peroxide gel as supplementary files
Authors: Parmar Devendra , Salvi Dhairya 
Published: October 2019

<p class="abstract"><strong>Background:</strong> Acne vulgaris is one of the commonest inflammatory skin disorders. It also has a psychosocial impact on patients, specially known in adolescents and hence needs effective treatment. The objectives of the study was to find out and ascertain different clinical presentations of acne vulgaris in both sexes of various age groups and to find out the outcome of treatment with various topical modalities in various clinical types.</p><p class="abstract"><strong>Methods:</strong> A total of 150 patients with acne vulgaris were studied with age group &gt;10 years. Detailed history, thorough physical examination and relevant investigations were done. Patients were divided into 2 groups of 75 each and each group received different treatment and were followed up at 4th, 8th and 12th week.<strong></strong></p><p class="abstract"><strong>Results:</strong> At the end of 12 weeks there was significant improvement in grade-II patients treated with cindamycin 1% gel.</p><p><strong>Conclusions:</strong> The results of the study show that different grades of acne vulgaris respond with different regimens. </p>
Bleomycin-induced flagellate pigmentation: a case report from North-East India
Authors: Thokchom Nandakishore , Bhattacharjee Nandita , Kongbam Linda 
Published: October 2019

<p class="abstract">Bleomycin is an antitumour antibiotic commonly used in the management of Hodgkin’s lymphoma and germ cell tumours. Flagellate pigmentation is a very specific and rare cutaneous adverse effect of bleomycin. It is characterised by linear, painless, pruritic, hyperpigmented lesions simulating marks of whiplashes over trunk and extremities. With the advent of targeted therapies resulting in the infrequent use of bleomycin, this unique side effect is also uncommonly encountered nowadays. Here, we report a case of bleomycin-induced flagellate pigmentation in a 35-year-old Indian female with ovarian teratoma. The characteristic patterned hyperpigmented patches developed following 2nd cycle of chemotherapy with bleomycin, etoposide and cisplatin.</p><p class="abstract"> </p>
A not so common cause for fever with rashes
Authors: Narasimhan Murali , Sathar Saju A. , Ramakrishnan Ramachandran 
Published: October 2019

<p class="abstract">Skin rashes that appear during febrile illnesses can be due to various infectious diseases and non-infectious conditions that can range from mild self-limiting diseases to potentially life threatening conditions. Hence a comprehensive knowledge of these diseases is required. A comprehensive history must be taken, including intake of any medications, contact with animals, recent travel, and trekking in various natural environments. Complete and thorough physical examination can provide clues to early diagnosis. Here we report a case which presented with high grade fever, generalized blanching maculopapular rashes, and headache. Close examination revealed a scrotal ulcer leading to the diagnosis of scrub typhus which was confirmed by ELISA and treated successfully with doxycycline.</p><p class="abstract"> </p>
Cutaneous sarcoidosis: a case report from North-East India
Authors: Thokchom Nandakishore , Kongbam Linda , Bhattacharjee Nandita 
Published: October 2019

<p>Sarcoidosis is a multisystem granulomatous disease of unknown aetiology. Cutaneous sarcoidosis is seen in up to one-third of patients and may be the first or the only clinical sign of the disease. We report a case of cutaneous sarcoidosis with lungs and renal involvement in a 28-year-old housewife. She presented with itchy reddish-brown indurated plaques on left cheek and back for 2 years. Skin biopsy revealed non-caseating epithelioid granulomas. Contrast enhanced computed tomography thorax showed focal consolidation and multiple enlarged mediastinal lymph nodes and serum angiotensin-converting enzyme level was raised. Since cutaneous manifestations of sarcoidosis are extremely variable, its early recognition can provide a clue to the diagnosis and its systemic involvement. </p>
Un modelo matemático en el proceso de corte unidimensional de materiales.
Authors: De León Rodríguez Narciso Rubén , Medina Mendieta Juan Felipe , Fuentes Garí Ernesto Roberto 
Published: October 2019

La investigación fue realizada con el objetivo de utilizar métodos matemáticos asociados a las técnicas de computación para establecer los planes de corte unidimensionales de materiales en industrias que, de una forma u otra, se ven involucradas en esta actividad durante el desarrollo del proceso productivo.El modelo matemático establecido tiene presente la minimización de los desperdicios, la disponibilidad de materia prima y la cantidad de unidades a cortar por tipo de pieza. Un sistema informático habilitado a tales efectos permite de forma automática, a partir de datos primarios ofrecidos por el usuario, modelar la situación en estudio, procesar el modelo matemático correspondiente e interpretar la solución del mismo (o sea, presentar el plan de corte unidimensional de materiales). Lo expresado en el párrafo anterior ha sido puesto en práctica para distintas entidades productivas con resultados favorables en todos los sentidos, lo que permite afirmar que los planes de corte unidimensionales de materiales pueden ser elaborados vinculando la modelación matemática con la utilización de paquetes de programas computacionales.El informe de resultados, artículo científico correspondiente, puede convertirse en un documento de consulta que ofrece una forma no muy usual en la dirección de los procesos de corte unidimensional de materiales en la industria. El interesado, al consultarlo, podrá apreciar cómo se puede influir significativamente en el ahorro de materia prima con un nivel superior en la organización y control del trabajo de la entidad productiva, e incluso, conocer una forma de modelar matemáticamente un problema de este tipo, con información sobre el soporte computacional y la interpretación de los resultados para preparar el plan de producción.
Diego José Abad, poeta universal
Authors: Fernández Valenzuela Benjamín 
Published: October 2019

Soslayando de propósito la poesía castellana de Diego José Abad, ya tan lustrosamente tratada por don Joaquín Antonio Peñalosa, cómo quisiéramos hoy por hoy, acercamos, encendidos por esta luz del apotegma cervantino, a la epopeya latina de Diego José Abad, universal en su vocación y en su evocación, en su contenido y en su forma, en su ambición de gloria y en su intención de universalidad, cuando celebramos el segundo centenario de los años de su gloria que, deben ser, al fin de cuenta, gloria nuestra.
Platonismo, división de la mente y la explicación aristotélica de la ἀκρασία
Authors: Salles Ricardo 
Published: October 2019

En un artículo publicado por la revista Diánoia en 1993 (R.Salles, 1993b), intenté mostrar que si Aristóteles adrnitiera que la ἀκρασία intencional es posible, la teoría de la acción que él propone en la Ética Nicomaquea (EN) generaría una contradicción. En un articulo publicado por la revista Dianoia en 1993 (R.Salles, 1993b), intente mostrar que si Aristóteles adrnitiera quela aKpacrta intencional es posible, la teoría de la acción que el presente trabajo es mostrar en la EN Aristótles sí admite dicha posibilidad
Ética y poética en Aristóteles
Authors: Araiza Jesús 
Published: October 2019

Puesto que, según Aristóteles, la poética se relaciona con otras ciencias,como la política y la retórica, es valido preguntarse, a su vez, si existen vínculos entre la ética y la poética. Es evidente que sí. Para mostrar esto, el artículo toma como base el adjetivo σπουδαῖος; que el estagirita usa en la definición de tragedia, pues dicho término se emplea en lugar de un posible nombre ἀρεταῖος; (de ἀρετή), el cual verosímilmente no existe en la lengua griega. La palabra σπουδαῖος, en efecto, entraña una connotación en la cual esta contenida la noción ἀρετή, según se indica en Categorías 8 y se constata en los tratados de ética. Por tanto, desde la definición misma de tragedia puede contemplarse cierta relación entre la ética y la poética.
Coloquio Internacional Noua tellus 2003
Authors: Molina José 
Published: October 2019

De lo que significa esta celebración y del esfuerzo y gusto por llevarla a cabo, es testimonio el discurso que pronunciara en la inauguración el Dr. Bulmaro Reyes Coria, repito, director de Noua tellus, revista a la cual felicitamos ad multos annos!
Juegos etimológicos en Eurípides
Authors: Rinaldi Daniel 
Published: October 2019

Los juegos etimológicos, basados en palabras con sonidos más o menos semejantes, ofrecen novedosas interpretaciones del significado verdadero de distintos términos. Eurípides siente un marcado interés por los juegos de palabras que muestran un origen y dan un significado a los nombres propios. En efecto, con estos juegos de palabras trata de reconocer la verdad, no para todos evidente, que se oculta en esos nombres y busca subrayar el muy estrecho vínculo que, según los griegos, existe entre el destino de un hombre y su propio nombre.
Aspectos lingüísticos de índole sistemática en las Instituciones de Justiniano
Authors: Vargas Valencia Aurelia 
Published: October 2019

Este artículo pone en evidencia aspectos que tienden a la sistematicidad en las Instituciones de Justiniano, primera parte del Corpus Iuris Civilis, una obra que ha tenido gran trascendencia en la historia jurídica de Occidente. Se muestra la coherencia en planos del texto como los que se refieren a la temática y al estilo, pero sobre todo a elementos lingüísticos —explicaciones etimológicas principalmente— que, por su frecuencia, dan al texto un carácter acorde con sus propósitos. Éstos fueron, como es sabido, la docencia del Derecho y los principios de ley vigentes en tiempos del emperador Justiniano (s. VI), quien a su vez actúa como recuperador de la jurisprudencia romana clásica y de la legislación imperial que le precedieron.
Villa di Mecenate: una disertación arqueológica de Pedro José Márquez
Authors: Valdés García Hilda Julieta 
Published: October 2019

Pedro José Márquez Durán radicó en Roma junto con sus hermanos de orden a causa del mandato de expulsión de Carlos III. Allí se dedicó al estudio de la teoría arquitectónica y estética. A finales del siglo xviii, el embajador español en Italia, José Nicolás de Azara, llevó a cabo una expedición en Tívoli, en el emplazamiento de las ruinas conocidas como la Villa di Mecenate, en la que participaron los dos pensionados de la Real Academia de Bellas Artes de San Fernando de Madrid, Silvestre Pérez y Evaristo del Castillo, y el jesuita mexicano Pedro José Márquez. Este último elaboró una disertación para defensa de la denominación del lugar.
Los argumentos a partir de las ciencias en el Peri ideōn
Authors: González Varela José Edgar 
Published: October 2019

En el tratado Sobre las Ideas (Peri ideōn) Aristóteles discute críticamente cinco argumentos platónicos a favor de la existencia de Ideas. En Metafísica A, 9 el mismo autor indica que tres de éstos son menos rigurosos que los otros dos. La interpretación usual sobre el Peri ideōn sostiene que su menor rigor se debe a que no son válidos para postular Ideas. En este trabajo propongo, contra esa tesis, una nueva interpretación del primer grupo de argumentos “menos rigurosos”: los argumentos a partir de las ciencias. De acuerdo con nuestra interpretación éstos son, en conjunto, válidos para concluir la existencia de Ideas.
XI Symposium Platonicum (Tokyo, 2-7 Aug. 2010)
Authors: Stavru Alessandro 
Published: October 2019

The International Plato Society, which now counts some 270 paid up members, has celebrated its IX Symposium Platonicum, wholly devoted to Plato’s Republic, on August 2010. After Mexico City, Perugia, Bristol, Granada, Toronto, Jerusalem, Würzburg, and Dublin, the IX triennial meeting took place at the Mita Campus of Keio University in Tokyo, with some 180 participants, some 20 papers read in plenary sessions and some 90 shorter papers read in parallel sessions, the whole being wisely steered by the President Noburu Notomi (Keio University) and the co-President Shinro Kato (Tokyo Metropolitan University). As customary, papers were read in one of the five official languages (English, Italian, French, German and Spanish).