bluuebunny/crossref_metadata_2025_split huggingface dataset:
The degree of collaboration between business units in diversified corporation: A strategic perspective
Authors: Verma Pratima , Kumar Vimal , Jha Ajay , Muthukumaar Vignaesh , Do Manh‐Hoang , Sharma Nagendra K. , Gupta Sachin 
Published: March 2020

AbstractThe Company's CEOs are always obsessed with diversification since the early 1960s and this belief is continuing to date. Diversified corporations run multiple businesses to generate various opportunities to gain competitive advantages and differentiate themselves in the market. This study considered the business strategy of business units (BUs) for diversified corporations. Based on the dominating strategy pursued by BUs, this study tried to investigate the level of collaboration between the BUs when these BUs have a similar strategy or different strategy. Thus, this article aims to examine the level of collaboration or coordination between BUs in Indian diversified companies. A survey was carried out with 107 companies for examination and these companies were chosen to be of different sizes and sectors. The findings represent that the level of collaboration is high when the BUs have a similar kind of business strategy while the level of collaboration is low when they have different kinds of business strategies. These findings are useful for the current organizations to seek collaboration between BUs in the diversified corporation.
Percutaneous coronary intervention of an anomalous coronary chronic total occlusion: The added value of three‐dimensional printing
Authors: Young Laura , Harb Serge C. , Puri Rishi , Khatri Jaikirshan 
Published: March 2020

AbstractThree‐dimensional (3D) printing has had an evolving role in cardiology, although has been largely reserved for planning of structural heart disease interventions. We present a case whereby multimodality imaging, including 3D printing, played a pivotal role in planning a technically feasible approach for complex percutaneous coronary intervention of a chronically occluded anomalous right coronary artery, with creation of a customized guide catheter.
Adult congenital pulmonary valve insertion using a new bioprosthetic aortic valve: Inspiris
Authors: Do‐Nguyen Chi Chi , Kilcoyne Maxwell F. , Stevens Randy M. , Starc James , Madan Nandini , Mahan Vicki , Mesia Cesar Igor , Moulick Achintya 
Published: March 2020

AbstractWe describe successful placement of the Inspiris Resilia aortic valve in the pulmonary position. This valve has advantages for immediate benefit and future percutaneous interventions, making it a promising prosthesis for adult congenital patients.
Hypervalent Iodine(III)‐Catalysed Enantioselective α‐Acetoxylation of Ketones
Authors: Hokamp Tobias , Wirth Thomas 
Published: March 2020

AbstractAn enantioselective catalytic synthesis of α‐acetoxylated ketones through I(I)/I(III) catalysis using a resorcinol/lactamide‐based chiral iodoarene is reported. Catalyst turnover by in situ generation of the active iodine(III) derivative is achieved by oxidation with mCPBA in the presence of acetic acid. The prior transformation of ketones to easily accessible acetyl enol ethers is beneficial and yields up to 97 % with enantioselectivities up to 88 % ee are obtained using only low catalyst loadings of only 5 mol % under mild reaction conditions.
The chemistry of fading Prussian blue fingerprints – Theoretical and experimental analysis of a “forensic dilemma“
Authors: Fischer Rachel , Oetken Marco 
Published: March 2020

AbstractLatente Fingerabdruckspuren lassen sich mit Hilfe von Berliner Blau als Negativbild visualisieren. Das Verfahren liefert detaillierte Fingerabdrücke und ist zugleich bei geringem Materialeinsatz in kurzer Zeit durchführbar. Bei der Anwendung auf Metallen wie z. B. Kupfer, Eisen oder Zink ist ein Nachteil der Methode feststellbar: Die blauen Negativbilder verblassen innerhalb von Minuten, wobei der Kontrast zur Unterlage geringer und eine Auswertung der Fingerabdrücke unmöglich wird. Das Phänomen der „verblassenden“ Berliner‐Blau‐Fingerabdrücke ist Gegenstand dieses Artikels. Ausgehend von einer Arbeitshypothese werden Modellexperimente dargestellt, die zur Verifikation der Hypothese und zu den daraus abgeleiteten Konservierungsmethoden führen.
Molecular Tuning Nanoarchitectonics for Molecular Recognition and Molecular Manipulation
Authors: Ariga Katsuhiko 
Published: March 2020

AbstractAlthough forefront research fields on molecular machineries and nano‐manipulation have been developed, their current achievements stay mostly in basic science and are far from practical usages in daily life. In this short review, interfacial nanoarchitectonics for structural and functional tuning of molecular machines, molecular receptors, and related molecular objects is conceptually overviewed towards possible applications. As their typical functions, regulation methods of molecular recognitions and the other functions in three mode, (i) fixed structure mode, (ii) switching mode, and (iii) tuning mode, are mainly discussed. The exemplified facts reveal great possibilities in molecular tuning at interfaces. The functional molecules immobilized at interfacial media can be manipulated in relation with macroscopic human motions, which would be one of the promising ways to use molecular‐level functions in life‐related activities.
Hollow Structure for Photocatalytic CO2 Reduction
Authors: Wang Zhiliang , Akter Monny Sabiha , Wang Lianzhou 
Published: March 2020

AbstractGreenhouse gas Carbon dioxide (CO2) emission has attracted world‐wide attention and urgent actions are needed to reduce the impact of CO2 on the climate change challenge. Photocatalytic CO2 reduction reaction (CO2RR) is regarded as a promising way for utilizing CO2 as a feedstock to produce value‐added chemicals driven by sustainable solar energy. Efficient photocatalysts are crucially important for achieving high performance CO2RR. Taking the advantages of hollow structure in light harvesting, large surface area and ability to enrich the local CO2 concentration, the hollow photocatalysts have demonstrated their great potential for photocatalytic CO2RR. Herein, we provide a concise overview on the mechanism, state‐of‐the‐art advances and future perspective in hollow structured photocatalysts for photocatalytic CO2RR.
Preparation of rapeseed oil with superhigh canolol content and superior quality characteristics by steam explosion pretreatment technology
Authors: Yu Gaiwen , Guo Tingting , Huang Qingde 
Published: March 2020

AbstractIn this study, rapeseed was pretreated by steam explosion pretreatment technology and subsequently pressed to prepare rapeseed oil. GC, UPLC, and HPLC techniques were employed to analyze the quality characteristics of the rapeseed oil, including the canolol content and other quality characteristics. Additionally, the effect of steam explosion pretreatment technology on the canolol content of rapeseed oil was studied and the formation mechanism of canolol elucidated. The results revealed that when the steam explosion pressure reached 1.0 MPa, the canolol content of the tested oil increased from 41.21 to 2,168.69 mg/kg (52.63‐fold increase) and that sinapic acid played a significant role in the conversion of canolol. Thus, the sinapine was converted into the intermediate (sinapic acid) by hydrolysis, which in turn was transformed into canolol through decarboxylation. The instantaneous high‐energy environment generated by steam explosion pretreatment could intensify the hydrolysis and decarboxylation reactions of sinapine and sinapinic acid, thereby significantly increasing the canolol content of the oil. To prove the superiority of steam explosion pretreatment, we compared it with other pretreatment technologies, including traditional high‐temperature roasting and popular microwave pretreatment. The results revealed that rapeseed oil prepared by steam explosion pretreatment displayed the best quality characteristics. This study can be a reference for the preparation process of rapeseed oil with superhigh canolol content and superior quality characteristics using steam explosion pretreatment.
Autophagy regulation by microRNAs: Novel insights into osteosarcoma therapy
Authors: Jamali Zeinab , Taheri‐Anganeh Mortaza , Shabaninejad Zahra , Keshavarzi Abdolkhalegh , Taghizadeh Hajar , Razavi Zahra Sadat , Mottaghi Reza , Abolhassan Mohammadreza , Movahedpour Ahmad , Mirzaei Hamed 
Published: March 2020

AbstractOsteosarcoma (OS) is a kind of primary bone cancer that is considered as the leading cause of children death. Surgery and chemotherapy are considered as common treatment approaches for OS; the rate of survival for patients is almost 60–70%. Besides the used therapeutic approaches, it seems that there is a crucial need to launch new treatments for OS. In this regard, more understanding about cellular and molecular pathways involved in OS can contribute to recovery and develop new therapeutic platforms. Autophagy is a cellular machinery that digests and degrades dysfunctional proteins and organelles, so it can regulate the cell proliferation and survival. Most of the time, OS cells use autophagy to increase their survival and proliferation and to gain the ability to resist chemotherapy. Although, there are several controversial evidences on how OS cells use autophagy. A variety of cellular and molecular pathways, that is, microRNAs (miRNAs) can modulate autophagy. MiRNAs are some endogenous, approximately 22 nucleotide RNAs that have an important role in posttranscriptional regulation of mRNAs by targeting them. There are many evidences that the various miRNA expressions in OS cells are dysregulated, so it can propel a normal cell to cancerous one by influencing the cell survival, apoptosis, and autophagy, and eventually increased chemoresitance. Hence, miRNAs can be considered as new biomarkers for OS diagnosis, and according to the role of autophagy in OS progression, miRNAs can use inhibiting or promoting autophagy agents. The present review summarizes the effects of aberrant expression of miRNAs in OS diagnosis and treatment with focus on their roles in autophagy.
R‐spondin‐mediated WNT signaling potentiation in mammary and breast cancer development
Authors: Tocci Johanna M. , Felcher Carla M. , García Solá Martín E. , Kordon Edith C. 
Published: March 2020

AbstractThe mammary gland is a secretory organ, which develops as a network of growing epithelial ducts composed of luminal and basal cells that invade the surrounding adipose tissue through a series of developmental cycles. Mammary stem cells (MaSCs) maintain an accurate tissue homeostasis, and their proliferation and cell fate determination are regulated by multiple hormones and local factors. The WNT pathway plays a critical role in controlling the enormous tissue expansion and remodeling during mammary gland development through the maintenance and differentiation of MaSCs, and its deregulation has been implicated in breast cancer (BC) initiation and progression. The R‐spondins (RSPOs) are four secreted proteins that strongly enhance target cell sensitivity to WNT ligands. Moreover, leucine‐rich repeat‐containing G‐protein‐coupled receptors (LGRs) 4–6 are considered obligate high‐affinity receptors for RSPOs and have been described as stem cell markers. Importantly, elevated RSPO expression has been recently identified in several tumor types from patients, including BC, and it has been reported that they play a significant role in mammary tumor progression in experimental models. In this review, exploring our present knowledge, we summarize the role of the RSPO‐LGR axis as a WNT‐enhancing signaling cascade in the MaSC compartment and during the normal and neoplastic mammary gland development. In addition, we include an updated expression profile of the RSPOs and their action mediators at the cell membrane, the LGRs, and the ubiquitin‐ligases ZNRF3/RNF43, in different BC subtypes. Finally and based on these data, we discuss the significance of tumor‐associated alterations of these proteins and their potential use as molecular targets for detection and treatment of BC.
American College of Clinical Pharmacy Global Health Practice and Research Network's opinion paper: Pillars for global health engagement and key engagement strategies for pharmacists
Authors: Crowe Susie J. , Karwa Rakhi , Schellhase Ellen M. , Miller Monica L. , Abrons Jeanine P. , Alsharif Naser Z. , Andrade Christina , Cope Rebecca J. , Dornblaser Emily K. , Hachey David , Holm Michelle R. , Jonkman Lauren , Lukas Stephanie , Malhotra Jodie V. , Njuguna Benson , Pekny Chelsea R. , Prescott Gina M. , Ryan Melody , Steeb David R. , Tran Dan N. 
Published: March 2020

AbstractThe scope of pharmacy practice in global health has expanded over the past decade creating additional education and training opportunities for students, residents and pharmacists. There has also been a shift from short‐term educational and clinical experiences to more sustainable bidirectional partnerships between high‐income countries (HICs) and low‐ to middle‐income countries (LMICs). As more institutional and individual partnerships between HICs and LMICs begin to form, it is clear that there is a lack of guidance for pharmacists on how to build meaningful, sustainable, and mutually beneficial programs. The aim of this paper is to provide guidance for pharmacists in HICs to make informed decisions on global health partnerships and identify opportunities for engagement in LMICs that yield mutually beneficial collaborations. This paper uses the foundations of global health principles to identify five pillars of global health engagement when developing partnerships: (a) sustainability, (b) shared leadership, (c) mutually beneficial partnerships, (d) local needs‐based care and (e) host‐driven experiential and didactic education. Finally, this paper highlights ways pharmacists can use the pillars as a framework to engage and support health care systems, collaborate with academic institutions, conduct research, and interface with governments to improve health policy.
Cuprous sulfide deposition method for visualization of latent fingermarks on unfired cartridge cases
Authors: Najdoski Metodija , Oklevski Slobodan , Demiri Sani , Stojkovikj Sasho 
Published: March 2020

AbstractA new chemical method for visualization of latent fingermarks on unfired cartridge cases is reported in this research. The method is based on two‐step immersion of the cartridge cases in aqueous solutions of sulfuric acid and acidified sodium thiosulfate at room temperature. The chemical reactions that are occurring on the cartridge case's surface are leading to deposition of material in the furrows between the papillary line ridges thus visualizing the latent fingermark. The qualitative chemical composition of the as‐deposited material was studied using X‐ray powder diffraction analysis thus revealing that it corresponds to a low‐crystalline hexagonal chalcocite phase cuprous sulfide (Cu2S). The performance of the method was studied on fresh and aged fingermarks, and according to the results, it can visualize latent fingermarks that are up to 9 months old. The newly proposed method provides good performance considering the most important qualitative and quantitative parameters that describe each fingermark, that is, satisfactory contrast between the papillary line ridges and the background furrows, possibility of recognizing the pattern of each fingermark (arch, loop, and whorl), clarity and continuity of the friction ridges, and clarity of the second level characteristics and features. The proposed method is simple, fast, inexpensive, and reliable.
A systematic review of argumentation related to the engineering‐designed world
Authors: Wilson‐Lopez Amy , Strong Ashley R. , Hartman Christina M. , Garlick Jared , Washburn Karen H. , Minichiello Angela , Weingart Sandra , Acosta‐Feliz Jorge 
Published: March 2020

AbstractBackgroundAcross academic disciplines, researchers have found that argumentation‐based pedagogies increase learners' achievement and engagement. Engineering educational researchers and teachers of engineering may benefit from knowledge regarding how argumentation related to engineering has been practiced and studied.Purpose/HypothesisDrawing from terms and concepts used in national standards for K‐12 education and accreditation requirements for undergraduate engineering education, this study was designed to identify how arguments and argumentation related to the engineering‐designed world were operationalized in relevant literature.MethodologySpecified search terms and inclusion criteria were used to identify 117 empirical studies related to engineering argumentation and educational research. A qualitative content analysis was used to identify trends across these studies.FindingsOverall, engineering‐related argumentation was associated with a variety of positive learner outcomes. Across many studies, arguments were operationalized in practice as statements regarding whether an existing technology should be adopted in a given context, usually with a limited number of supports (e.g., costs and ethics) provided for each claim. Relatively few studies mentioned empirical practices, such as tests. Most studies did not name the race/ethnicity of participants nor report engineering‐specific outcomes.ConclusionsEngineering educators in K‐12 and undergraduate settings can create learning environments in which learners use a range of epistemic practices, including empirical practices, to support a range of claims. Researchers can study engineering‐specific outcomes while specifying relevant demographics of their research participants.
Is bone mineral density lower in the necrotic lesion in pre‐collapse osteonecrosis of the femoral head?
Authors: Baba Shoji , Motomura Goro , Ikemura Satoshi , Yamaguchi Ryosuke , Utsunomiya Takeshi , Hatanaka Hiroyuki , Kawano Koichiro , Xu Mingjian , Nakashima Yasuharu 
Published: March 2020

AbstractThe purpose of this study was to clarify whether bone mineral density (BMD) of the necrotic lesion in precollapse osteonecrosis of the femoral head (ONFH) is reduced according to Hounsfield unit (HU) values on computed tomography (CT). The superior one‐third of the femoral head in the coronal section was set as the region of interest (ROI) for the measurement of HU values. First, HU values of 101 control participants were assessed to identify relevant confounding factors. Next, the relationship between HU values and BMD on dual‐energy X‐ray absorptiometry (DXA) was verified. Then the mean HU value of the ROI in patients with pre‐collapse ONFH was compared with that in propensity score‐matched control participants. Finally, the HU values of the lateral boundary in the patients with and without subsequent collapse were compared. Multivariable analysis showed that both age and BMI were significantly correlated with the HU value, which showed a strong correlation with the BMD of the femoral neck on DXA (r = 0.92). In 25 ONFH patients and 25 propensity‐matched control participants, no significant difference was found in the HU value of the ROI (p = .54). The mean HU value of the lateral boundary in patients with subsequent collapse was found to be significantly higher than that in patients without subsequent collapse (p < .01). The assessment of HU values on CT was useful for the evaluation of BMD of the femoral head. The current assessment did not demonstrate reduced bone mineral density of the necrotic lesion in pre‐collapse ONFH
Do patients with aggressive and chronic periodontitis exhibit specific differences in the subgingival microbial composition? A systematic review
Authors: Montenegro Sheyla Christinne Lira , Retamal‐Valdes Belen , Bueno‐Silva Bruno , Duarte Poliana Mendes , Faveri Marcelo , Figueiredo Luciene Cristina , Feres Magda 
Published: March 2020

AbstractBackgroundThe 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions grouped the diseases previously recognized as chronic (CP) or aggressive (AgP) periodontitis under a single category named periodontitis. The rationale for this decision was the lack of specific patterns of immune‐inflammatory response or microbial profiles associated with CP or AgP. However, no previous studies have compiled the results of all studies comparing subgingival microbial data between these clinical conditions. Thus, this systematic review aimed to answer the following focused question: “Do patients with AgP periodontitis present differences in the subgingival microbiota when compared with patients with CP?”MethodsA systematic review was conducted according to the PRISMA statement. The MEDLINE, EMBASE, and Cochrane databases were searched up to June 2019 for studies of any design (except case reports, case series, and reviews) comparing subgingival microbial data from patients with CP and AgP.ResultsA total of 488 articles were identified and 56 were included. Thirteen studies foundAggregatibacter actinomycetemcomitanselevated in AgP in comparison with CP, whileFusobacterium nucleatum, Parvimonas micra, andCampylobacter rectuswere elevated in AgP in a few studies. None of these species were elevated in CP. However, the number of studies not showing statistically significant differences between CP and AgP was always higher than that of studies showing differences.ConclusionThese results suggested an association ofA. actinomycetemcomitanswith AgP, but neither this species nor the other species studied to date were unique to or could differentiate between CP and AgP (PROSPERO #CRD42016039385).
Kinetic modeling of the ethylbenzene/xylene isomerization reaction over HZSM‐5 zeolites revisited
Authors: Farahani Shokoufeh Hosseinieh , Falamaki Cavus , Alavi Seyed Mehdi 
Published: March 2020

AbstractIn this article, a binderless dealuminated HZSM‐5 zeolite (Si/Al = 41.4) was used as a catalyst for the isomerization of a mixture of ethylbenzene and xylene. The experimental results indicated that at low residence times the catalyst is effective to isomerize the ethylbenzene into xylenes. A comprehensive kinetic model considering chemisorption, surface chemical reactions, and diffusional processes was developed for this reaction. The intrinsic activation energy (71.99 kJ mol−1) for the surface reaction of ethylbenzene into m‐xylene was calculated for the first time, and the corresponding intrinsic activation energies for o‐xylene to m‐xylene and m‐xylene to p‐xylene surface reactions were calculated to be 59.45 and 50.68 kJ mol−1, respectively. Lower apparent values have been reported in the literature, and we rationalize that they correspond to multistep processes and intrinsically include a negative activation energy pertaining to chemisorption. The results also revealed that the ethylbenzene diffusion within the zeolite channels was four orders of magnitude smaller than p‐xylene.
One‐Step Microwave Approach to Generate Carbon Dots/Gelatin Composite with Both Thermoresponsive Sol–Gel Transition and Fluorescence Properties
Authors: Wang Xia , Liu Hui , Wu Wencheng , Xiong Yanfei , Chen Wei , Cao Kaiyuan , Wang Yifeng , Chen Yanjun 
Published: March 2020

AbstractCarbon dots (CDs) have drawn considerable research interest for their attractive applications in sensors, bioimaging, and photonic devices. Here, an aqueous gelatin solution is employed as the only reactant to directly generate a CDs/gelatin composite through a green and simple one‐step microwave approach. The resulting CDs/gelatin composite owns a typical excitation‐dependent photoluminescence property that comes from CDs, which can be potentially applied for multicolor fluorescence bioimaging. More importantly, the CDs/gelatin composite possesses a thermoresponsive sol–gel transition property that is associated with gelatin, which can be exquisitely enlisted to fabricate CDs/gelatin gel beads and fluorescent gel patterns. Also the release of CDs from the gel beads can be triggered by the thermoresponsive sol–gel transition. Thus, for the first time this study creates the CDs/gelatin composite with both thermoresponsive sol–gel transition and fluorescence properties, which is promising for applications in stimuli‐responsive materials, nanocomposites, controlled release, and fluorescence imaging.