bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Shirom-Melamed Vigor Measure for students and how vigor relates to academic performance, mental health and satisfaction with life: Factorial analysis and construct validity in Spanish undergraduate university students
Authors: Pulido-Martos Manuel , Cortés-Denia Daniel , Rosa-Blanca Juan José de la , Lopez-Zafra Esther 
Published: June 2020

Abstract
Background

Students suffer from a decrease in physical activity during their education period. This lower level of activity could affect, through various paths, their academic performance, mental health and satisfaction with life. In this study, we assume that vigor, a positive affect variable, would act as a mediating variable in the above relationship, and thus, we propose an instrument for evaluating vigor in academic contexts. To attain this aim, the factorial validity and reliability of the proposed vigor scale for students is tested (Study 1), along with its construct validity (Study 2).
Methods

In Study 1, 707 undergraduates (59.7% women) responded to the vigor scale adapted for students to test factorial validation (through confirmatory factor analysis) and obtain reliability indicators. In Study 2, 309 undergraduates (55.3% women) completed a questionnaire measuring physical activity, mental health, satisfaction with life, vigor and academic performance to test a structural model of the relationships between the variables to obtain construct validity.
Results

A measurement model with three related factors, each representing one dimension of vigor, optimally fit the data (S-Bχ2 = 231.54; df = 50; CFI = 0.95; NNFI = 0.93; SRMR = 0.07; RMSEA = 0.07 [0.06–0.08]), and the reliability indices were adequate (Study 1). In Study 2, the mediational model confirmed a complete influence of physical activity on satisfaction with life, academic performance and mental health levels through the levels of vigor of the students, with optimal adjusting values (S-Bχ2 = 108.82; df = 62; p < 0.001; CFI = 0.92; NNFI = 0.90; SRMR = 0.05; RMSEA = 0.05 [0.03–0.06]).
Conclusions

Proposing an instrument such as the Shirom-Melamed Vigor Measure for students allows the opening of a research venue that is focused on the study of positive affects in academic contexts, as well as the testing of the physical activity pathways of action in obtaining positive results.
Development and Validation of a Decisional Balance Tool to Assess Perceived Benefits and Barriers of Vegetable Consumption in Adults
Authors: Kawaguchi Yaeko , Somei Junichiro , Kawaguchi Chikana , Suganuma Akiko , Nirengi Shinsuke , Sakane Naoki 
Published: June 2020

Abstract
Background: The aim of this study was to develop and validate a decisional balance tool for assessing the perceived benefits and barriers of vegetable intake in adults. Methods: Our study comprised 379 adults aged 20–70 years (mean age: 30.5 ± 12.6 years; men: 21.4%). Data (demographic parameters, vegetable intake, stage of change) were collected via a web-based survey. The decisional balance score was calculated by subtracting the score for perceived barriers from the score for perceived benefits.Results: The final 24 items in our questionnaire had a two-domain (“pleasure” and “healthy” for perceived benefits) or three-domain (“not attractive,” “low priority,” and “hard to get” for perceived barriers) structure with high internal consistency (Cronbach’s alpha: 0.82, 0.79, 0.82, 0.76, and 0.76, respectively). The intraclass correlation coefficient in a test-retest reliability study was high (0.77). The decisional balance score positively correlated with the number of vegetable servings as the external parameter (Spearman's correlation: 0.461; P <0.001).Conclusions: Our questionnaire is a valid and reliable tool for assessing the pros and cons of vegetable consumption in adults.
Risk factors of lymph node metastasis in the splenic hilum of gastric cancer patients: A meta-analysis
Authors: Du Jun , Shen Yangchao , Yan Wenwu , Wang Jinguo 
Published: June 2020

Abstract
Background It remains controversial whether splenic hilum lymph nodes (SHLNs) should be excised in radical gastrectomy with D2 lymph node dissection. In this study, we evaluated the role of clinicopathological features in patients with gastric cancer in predicting splenic hilum lymph nodes metastasis.Methods We searched the Medline, Embase, PubMed and Web of Science databases from inception to May 2020 and consulted related references. 15 articles with a total of 4377 patients were included finally. The odds ratios (ORs) of each risk factor and the corresponding 95% confidence interval (CI) were determined using Revman 5.3 software. Results Meta-analysis showed that tumor size greater than 5 cm (p < 0.01), tumor localization in the greater curvature (p < 0.01), diffuse type (Lauren’s type) (p < 0.01), Borrman type 3–4 (p < 0.01), poor differentiation and undifferentiation (p < 0.01), depth of invasion T3–T4 (p < 0.01), number of lymph node metastases N2–N3 (p < 0.01), distance metastasis M1 (p < 0.01), TNM stage 3–4 (p < 0.01), vascular invasion (p = 0.01), and lymphatic invasion (p < 0.01) were risk factors of SHLNs metastasis. Moreover, No. 1-, 2-, 3-, 4sa-, 4sb-, 4d-, 6-, 7-, 9-, 11-, and 16-positive lymph node metastasis are strongly associated with splenic hilum lymph nodes metastasis.Conclusions Tumor size, tumor location, Lauren’s type, Borrman type, degree of differentiation, T stage, N stage, M stage, TNM stage, vascular invasion, lymphatic infiltration, and other positive lymph nodes metastasis were risk factors for SHLNs.
A Processing Method for Kinematics Data of Human Knee Joint Obtained by Motion-Capture Measurement
Authors: Wang Jian-ping , Wang Shi-hua , Zhao Xuan , Hu Hai , Wang Yan-qing , Liu Jin-lai , Chen Xu , Li Yu 
Published: June 2020

Abstract
Background: The data obtained by motion capture method is many and complex, so it is the key to find an efficient method to process the data. Therefore, to develop a processing method for kinematics data of human knee joint by programming on MATLAB sofware. Methods: The coordinate data of markers on human lower limb measured by motion capture system were firstly read and repaired through the program. Then the coordinate data of anatomical points in the movement of human lower limb were obtained by program processing. The local coordinate systems of human femur and tibia were established with anatomical points. After that the flexion/extension, abduction/adduction and internal/external rotation of human knee tibiofemoral joint in the movement of lower limb were obtained by coordinate transformation. Lastly, the motion capture and measurement of healthy volunteers were carried out and the MATLAB program was used for data processing.Results: Using the above methods, motion capture measurements and batch data processing were carried out on squatting and ascending stairs of 29 healthy volunteers to obtain the motion characteristics of the knee joint. As follows, the maximum range of internal and external rotation in squatting is 30.5 degrees, and the maximum range of internal and external rotation in climbing stairs is 16.5 degrees, etc., respectively compared with the results processed by other research methods, it is found that their movement results are basically consistent, thus verifying the reliability of our research method.Conclusion: The kinematics data of human knee joint could be processed accurately and effectively with the method by using MATLAB software, and the kinematics characteristics of human knee tibiofemoral joint were obtained. The processing method provides a reference for the designing and optimization of knee prosthesis, and the program can be modified for different purposes. At the same time, it is helpful to study knee joint movement of patients after total knee arthroplasty. Keywords: Knee joint, Motion capture measurement, MATLAB, Kinematics
Refined tumescent liposuction-curettage with pruning in small incisions for treatment of axillary bromhidrosis
Authors: Li Cai-Yun , Wang Xiao-Feng , Zhou Hai-ying , Fang Qing-Qing , Tan Weiqiang 
Published: June 2020

Abstract
Background
Axillary bromhidrosis is widespread social problem in our society. Various modalities have been developed for destruction or removal of the apocrine sweat glands to eliminate the malodor. But conventional surgical treatments often result in high complication rate and frequent recurrence. In the study, we evaluate the effect of refined tumescent liposuction-curettage with pruning in small incisions in the treatment of axillary bromhidrosis.
Methods
From July of 2013 to April of 2019, 110 patients (75 women and 35 men) with axillary bromhidrosis were treated by refined tumescent liposuction-curettage with pruning. The results of malodor elimination were evaluated by both the patients and doctors as very satisfied (excellent), satisfied (good), some satisfied (fair), and not satisfied (poor). Postoperative complications, including dehiscence, infection, wound contracture, cyst, subcutaneous hydrops, haematoma or seroma were evaluated as well. Preoperative and postoperative histological examinations of axillary tissue were performed in 2 patients.
Results
Among subjective evaluation of the 110 patients, 33 (30.0%) were graded as very satisfed results, 70 (63.6%) were satisfied, and 7 (6.4%) was some satisfied. The objective evaluation showed 43 (39.1%) were graded as excellent results and all the others were good. No serious complications were happened except three showed slightly local subcutaneous hydrops and haematoma. Histologic examinations showed the apocrine glands significant decreased or destroyed after surgery.
Conclusion
Refined tumescent liposuction-curettage with pruning in small incisions is an effective method for treatment of axillary bromhidrosis.
The use of ultrasound to locate a tethered surgical drain: a novel way to achieve fast removal
Authors: Li Hui , Du Yan , Wu Jia-bin , Wang Pan , Yang Jun , Hu Ping , Ai Tao 
Published: June 2020

Abstract
Background
It is rare that drains cannot be removed after surgery, however, this situation cannot be completely avoided, and is also hard to deal with. The main reason for a tethered drain is inadvertent suture fixation. At present, no effective way was published or widely accepted to locate the tethered drain.
Methods
Three cases of orthopedic trauma patients experienced unsuccessful removal of the drain after surgery. The ultrasound was used to locate the sutured site of the drain. Based on the sliding sign and vanishing point which can be detected by the ultrasound, the sutured site of the drain can be clearly identified. Finally, the suture was loosened through a small incision, and the drain was completely removed.
Results
The surgical procedure was very successful in all patients. The tethered drain was quickly and completely removed through a small incision with locating by ultrasound. Intravenous antibiotics were administered within 24 hours after surgery, and no wound or deep infections occurred.
Conclusions
Ultrasound can be used to locate a tethered drain based on the sliding sign. This method can simplify the release procedure and achieve fast removal of the drain. Furthermore, it will help lower the risk of a retained drain and soft tissue complications.
Ureteroscopic lithotripsy combined with stent placement contributed to long-term auto-release of lithangiuria in upper urinary tract after ureterolithotripsy
Authors: Sun Liujing , Zhao Jun 
Published: June 2020

Abstract
Background

To investigate the clinical efficiency of ureterectasis combined with stent placement in the long-term auto-release of lithangiuria in upper urinary tract after ureterolithotripsy.
Methods

In this retrospective analysis, we included the patients (male: 314; female: 49; age: 32–78 yrs; median age: 53 yrs) admitted to our hospital between January 2014 and January 2018 underwent ureterolithotripsy (URS group, n = 178) and extracorporeal shock wave lithotripsy (ESWL group, n = 212) for treating lithangiuria in upper urinary tract. All the patients were followed up for 24–59 months after treatment (median: 38 months). Uni-variate and multi-variate Logistic regression analysis was used to analyze the factors that could affect the long-term release of lithangiuria in upper urinary tract. Then we compared the short diameter of the ureter surpassing the stenosis of iliac vessels and the long-term auto-release of lithotripsy between the two groups.
Results

Logistic regression analysis indicated that the risk of auto-release of the stones in the upper urinary tract in the URS group was significantly higher than that of the ESWL group (OR = 3.357, 95% CI: 1.234–9.137). Stent placement was an independent risk factor for long-term auto-release of lithotripsy (P < 0.01). The short diameter of the ureter surpassing the stenosis of iliac vessels after URS was significantly longer than that of the baseline level (6.06 ± 1.26 mm vs. 3.63 ± 0.98 mm, t = 20.88, P < 0.01). The short diameter of the ureter surpassing the stenosis of iliac vessels after ESWL showed no statistical differences compared with that of the baseline level (3.67 ± 1.02 mm vs. 3.61 ± 0.94 mm, t=-0.798, P = 0.425). Sixteen cases (2.8%) in the URS group showed auto-release of stones during the follow-up, which was significantly higher than that in the ESWL group with 6 cases (13.5%) presented auto-release of stones (χ2 = 6.895, P = 0.09).
Conclusions

The combination of URS and stent replacement induced obvious ureterctasis, which may contribute to the auto-release of stones in the upper urinary tract in the long-term.
Secondary Primary Lung Cancer After Esophageal Cancer: A Population-Based Study of 44,172 Patients
Authors: Gao Yadong , Qiu Jianwei , Gu Liugen , Yang Yanmei , Kang Haifeng , Zhang Yong , Zhang Yan , Zhang Shenglai , Qian Junbo 
Published: June 2020

Abstract
Background: The present study aimed to assess the incidence, characteristics, and survival of secondary primary lung cancer after primary esophageal cancer (EC-LC). Methods: The patients with esophageal cancer (EC) who developed SPLC and patients with first primary lung cancer (LC-1) were retrospectively reviewed in the Surveillance, Epidemiology, and End Results 18 registries covering 2000 to 2016. The risk of secondary primary lung cancer using standardized incidence ratio (SIR) was calculated among patients with EC. Overall survival and characteristics were compared between patients with EC-LC and patients with LC-1.Results: In comparison with the general population, the patients with EC had a higher risk for developing secondary primary lung cancer (SIR =1.86, 95% confidence interval (CI): 1.69-2.05). There was a significant difference with regard to the year of diagnosis, sex, grade and stage between the secondary primary lung squamous carcinoma after EC (EC-LUSC) and first primary lung squamous carcinoma (LUSC-1) patients. A statistically significant difference with respect to race, sex, age, year, grade and stage was found between the secondary primary lung adenocarcinoma after EC (EC-LUAD) and first primary lung adenocarcinoma (LUAD-1) patients. A history of EC was found to be an independent risk factor of death for lung squamous carcinoma and lung adenocarcinoma patients in localized stage based on multivariate Cox regression analysis, propensity score-matching analysis and multiple imputation.Conclusion: There is a significantly increased risk of secondary primary lung cancer in EC survivors and a history of EC adversely affects overall survival in individuals who subsequently develop localized EC-LUSC and EC-LUAD. Clinicians should moderately strengthen lung tissue protection during the management of EC patients.
Mir-20a-5p Induced WTX Deficiency Promotes Gastric Cancer Progressions Through Regulating PI3K/AKT Signaling Pathway
Authors: Li Jian , Ye Danli , Shen Peng , Liu Xiaorong , Zhou Peirong , Zhu Guifang , Xu Yangwei , Fu Yun , Li Xuanqi , Sun Jingbo , Xu Jia , Zhang Qingling 
Published: June 2020

Abstract
Background: The X-linked gene WTX (also called AMER1), has been reported to act as a tumor suppress gene in Wilms tumor. Our previous study reported that WTX expression was significantly reduced in gastric cancer (GC), but the function and mechanism of WTX loss had not been fully elucidated yet. Methods: WTX/miR-20a-5p expression was analyzed in paraffin-embedded archived GC tissues and validated in public databases. KEGG pathway analyses were performed to explore the mechanism of WTX in GC progression. The role of WTX/miR-20a-5p in cell growth, migration, invasion and angiogenesis was investigated in vitro and in vivo. Western blot, immunohistochemistry, RT-PCR, luciferase assay, and Co-immunoprecipitation (Co-IP) were used to detect the regulation of WTX and PI3K/AKT/mTOR signaling by miR-20a-5p.Results: We revealed that WTX served as a tumor suppressor whose loss associated with the aggressive feature of GC by showing hyperproliferation in vitro and high metastasis phenotype in vivo. And WTX expression level was positively correlated with the overall survival of GC patients. Microarray, bioinformatics analysis, and verification experiments showed that WTX loss activated PI3K/AKT/mTOR pathway, and promoted the proliferation and invasion of GC cells. We also discovered that the miR-20a-5P aberrant upregulation was one of the reasons inducing WTX loss in GC which stimulated PI3K phosphorylation to activate PI3K/AKT/mTOR signaling pathway, thus promoted GC progression.Conclusions: This study unveiled the mechanism of GC progression which was, at least partially, caused by miR-20a-5p aberrant upregulation which inhibited WTX expression and thus activate PI3K/AKT/mTOR signaling pathway. It provided a comprehensive understanding of the action of miR-20a-5p/WTX/PI3K/AKT/mTOR signaling pathway in the progression and metastasis of GC.
International Research Collaborations on COVID-19 Amidst Geopolitical Tensions with China
Authors: Lee Jenny J. , Haupt John P. 
Published: June 2020

Abstract
As the threat of COVID-19 and US-China tensions are increasing, this study focused on this intensifying intersection between geopolitics and global science in the midst of a pandemic. This scientometric study compared proportions of international S&E collaborations during and before COVID-19 by countries through the lenses of scientific nationalism and scientific globalism. Social network analyses were also conducted to observe the various ties between countries on S&E COVID-19 publications, with a particular focus on China. While scientific nationalism would assume that the current political rhetoric and protectionist policies would lead to a decrease in international collaboration, our findings showed the reverse. The proportion of international collaborations and extent of multilateralism generally increased. Findings also revealed that despite geopolitical tensions and China’s recently introduced publication evaluation policy, the US and China remain the world’s leading international collaborators, including on S&E COVID-19 research.
Diminished Corticomotor Excitability in Gulf War I Veterans with Chronic Pain Symptoms
Authors: Lei Karen , Kunnel Alphonsa , Metzger-Smith Valerie , Golshan Shahrokh , Javors Jennifer , Wei Jennie , Lee Roland , Vaninetti Michael , Rutledge Thomas , Leung Albert 
Published: June 2020

Abstract
Background: Diminished motor cortical excitability, as a measurement of increased resting motor threshold with transcranial magnetic stimulation (TMS), is known to be associated with chronic pain conditions. Over 175,000 veterans who were deployed to the Persian Gulf in 1990-91 suffer from an unexplained multisymptom illness termed Gulf War Illness (GWI) with chronic headaches and diffuse body pain as the most commonly reported symptoms. This study hypothesized that veterans with Gulf War Illness related pain exhibit diminished corticomotor excitability associated with chronic pain states and aimed to assess the resting motor threshold (RMT) at the primary motor cortex (M1) in veterans with GWI.Methods: Single pulse TMS was administered over the left motor cortex, using anatomical scans of each subject to guide the TMS coil, starting at 25% of maximum stimulator output (MSO) and increasing in steps of 2% until a motor response with a 50 µV peak to peak amplitude, defined as the RMT, was evoked at the flexor pollicis brevis muscle. RMT was then analyzed using Repeated Measures Analysis of Variance (RM-ANOVA).Results: Gulf War Veterans (GWV) with chronic headaches and body pain (N=20) had a significantly (P<0.001) higher average resting motor threshold (%± SD) of 77.2%±16.7% compared to age and gender matched GWV Controls (N=20), whose average was 55.6%±8.8%.Conclusion: This study demonstrated that a higher level of stimulation was required to evoke a motor response in veterans with GWI related pain. This diminished corticomotor excitability that suggests a reduced state of supraspinal pain modulatory function. Though further studies will be needed, TMS may provide a means of effectively rectifying this modulatory deficit.
Mortality calculator as a possible prognostic predictor for overall survival after gastrectomy in elderly patients with gastric cancer
Authors: Akaike Hidenori , Kawaguchi Yoshihiko , Maruyama Suguru , Shoda Katsutoshi , Satio Ryo , Furuya Shinji , Hosomura Naohiro , Amemiya Hidetake , Kawaida Hiromichi , Sudoh Makoto , Inoue Shingo , Kohno Hiroshi , Ichikawa Daisuke 
Published: June 2020

Abstract
Background The number of elderly patients with gastric cancer (elderGC) has been increasing. Most of elderly patients were associated with reduced physiological functions, which sometimes constitute an obstacle to safe surgical treatments. The risk calculator of National Clinical Database (NRC), a Japanese surgical big database, provides mortality and morbidity as surgical-related risks. The purpose of this study is to investigate clinical significance of operative mortality calculated by NRC (NRC-mortality) during long-term follow-up after gastrectomy for elderGC.Methods We enrolled 73 patients aged 80 or over who underwent gastrectomy at our institution. Their surgical risk was evaluated based on the NRC-mortality. Several clinicopathological factors including NRC-mortality were selected and analyzed as possible prognostic factors for elderGC after gastrectomy. Statistical analysis was performing using the log-rank test and Cox proportional hazard model.Results NRC-mortality ranged 0.5 to 10.6%, and median value was 1.7%. Dividing elderGC into high- (1.7% or more, n=38) and low- (less than 1.7%, n=35) mortality groups, high-mortality group showed a significantly poor prognosis in overall survival (OS) than the low-mortality group, whereas there was no difference between the two groups in disease specific survival (DSS). In the analysis of Cox proportional hazard model, multivariate analysis revealed that NRC-mortality was an independent prognostic factor as well as neutrophil-lymphocyte ratio and surgical procedure in OS. In contrast, PS and pStage were independent prognostic factors in DSS, but not NRC-mortality.Conclusions The NRC-mortality might be clinical useful for not only predicting surgical mortality but also OS after gastrectomy in elderGC.