bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spinal anesthesia for cesarean section in preeclampsia
Authors: Bashar Md Abul , Akter Nargis , Ali Mohammad , Jahan Kazi lsrat , Mazumder Mohammad Zahldur Rahman , Morshed G M 
Published: November 2020

Background: Pregnancy-induced hypertension constitutes a major cause of morbidity and mortality in developing nations and it complicates about 6-8% of pregnancies. Severe preeclampsia poses a dilemma for the anesthesiologist especially in emergency situations where caesarean deliveries are planned for uninvestigated or partially investigated parturients. The choice of anesthesia in preeclamptic mothers undergoing Cesarean delivery has been debated for years. General as well as regional anesthetic techniques are equally acceptable for cesarean delivery in pregnancies complicated by preeclampsia. Currently, the safety of regional anesthesia technique is well established and they can provide better obstetrical outcome.
Objective: To study the outcome and elaborate the hemodynamic changes associated with spinal anesthesia in preeclampsia.
Methods: The study was carried out in com ii la medical college hospital and private clinics in comilla among preeclamptic women who underwent Lower Segment Caesarean Section (LSCS) under spinal anesthesia between January 2013 and July 2017. Both emergency as well as elective cases were included in the study. Patients' records were studied and analyzed. The drug used for spinal anesthesia was hyperbaric Bupivacaine 0.5%. Subarachnoid block was performed in either L3-L4 or L2-L3 intervertebral segment with patient sitting up. Spinal needle 25G was used. The hemodynamic response (systolic blood pressure, diastolic blood pressure, heart rate) and Sp02 were observed.
Results: Total of 310 cases was included in our study. Age ranged from 17 to 37 years. The duration of surgery ranged from 25mins to 100mins. According to observation, both systolic and diastolic blood pressure dropped to minimum within the initial 10 minutes of spinal anesthesia. Heart rate fluctuation was minimal with an initial small drop within 10 minutes of spinal anesthesia. Similarly, Sp02 also showed a subtle decline within 20 minutes of spinal anesthesia.
Conclusion: Our study finds spinal anesthesia as a preferred method taking into account the relatively stable and better hemodynamic stability, convenience in procedure and rapid and predictable anesthesia and no risks of sudden critical hypotension.
Journal of Surgical Sciences (2018) Vol. 22 (1): 30-35
Management of duodenal stump fistula following gastrectomy for gastric cancer: a systematic review
Authors: Zico Nahid Rahman , Kabir Faisol 
Published: November 2020

Introduction: Duodenal stump fistula (DSF) after gastrectomy has a low incidence but a high morbidity and mortality, and is therefore one of the most aggressive and feared complications of this procedure. This study was designed to assess the most effective treatment of duodenal stump fistula (DSF) after gastrectomy for gastric cancer.
Methods: A systematic analysis of PubMed, MEDLINE, Current Contents, UpToDate databases, and the Cochrane Library Databases were carried out. A total of 80 manuscripts were retrieved and screened and nine studies published between 2009 and 2016 were selected. 241 cases of DSF were included in the study according to inclusion criteria. Only patients who underwent gastrectomy for gastric cancer were included in our review. Data about patient's characteristics, types of treatment, short and long-term outcomes were extracted and analyzed.
Results: Three different approaches were applied: conservative (75 cases), surgical (138 cases) and percutaneous (59 cases). The overall mortality rate was 19% and significant complications were identified in 21% cases. Significant complications included sepsis, abscesses, peritonitis, bleeding, pneumonia and multiple organ failure. The conservative approach was reported in 5 studies including 75 patients who were clinically stable and complete resolution occurred in 92.3% of patients with a mean healing time of 35 days. Surgery was carried out if the patient was haemodynamically unstable or showed signs of sepsis. Overall outcome after surgery was poor with 31.1% mortality derived from six studies and in-hospital stay ranged from 1 to 1035 days (median 19). Percutaneous approach was often associated with conservative treatment and consisted of abscess drainage, biliary drainage or biliary diversion. The median healing time in this group was 42 days.
Conclusion: Conservative approach is the first line of treatment in DSF, sometimes associated with percutaneous approach. Surgery should be reserved for severe cases or when conservative measures fail.
Journal of Surgical Sciences (2018) Vol. 22 (1) : 62-66
Outcome of Non-operative Management of Perforated Peptic Ulcer Disease
Authors: Shashi Sanjana Sharmin , Hossain AZM Shakhwat , Bar Debashish , Rahman Ayesha , Reza AFM Muntahi , Rashid Muhammad Harun Ar 
Published: November 2020

Background: Peptic ulcer perforation management is still an enigma. Though the overall incidence has been reduced worldwide due to wide use of anti-ulcerants, still it is not uncommon. But there is a debate regarding its conservative management over surgical management.
Objective: To determine whether surgery could be avoided in selected patients with perforated peptic ulcer disease
Methods: This study was conducted in the department of Surgery of Sir Salimullah Medical College and Mitford Hospital during the period from 1st March 2016 to 31st August 2016. After approval from the institutional ethics committee, 30 patients of suspected perforated peptic ulcer disease were successively assigned in this study on clinical and radiological basis. All were given non-operative regimen up to 24 hours. Then they were closely monitored to see improvement of clinical condition or development of any complication. Non-operative treatment was abandoned if the patient failed to improve or deteriorated within 24 hours of non-operative treatment. The data were collected by active participation of patients’ interview in preformed data collection sheet. Results: The data analysis of 30 patients yielded that most of them (86.67%) recovered well after receiving non-operative management, whereas only 4 patients (13.33%) showed no progression and were treated by laparotomy. 73.08% patients with uneventful outcome left the hospital within 10 days of admission and the others were a little late to leave.
Conclusion: Patients with perforated peptic ulcer disease can be effectively treated by conservative approach in properly selected cases by proper monitoring under strict supervision of an experienced consultant.
Journal of Surgical Sciences (2018) Vol. 22 (2) : 95-98
Bile Duct Injury- A Health and Financial Disaster
Authors: Saha Tapan Kumar , Talukder Tuhin , Hoque Md Rajibul 
Published: November 2020

Bile Duct Injury (BDI) is an unfortunate complication of cholecystectomy, if not treated properly may result in the death of the patient due to biliary peritonitis and sepsis or may convert an otherwise healthy young person with a biliary cripple with benign biliary stricture (BBS), cholangitis, secondary biliary cirrhosis, portal hypertension & liver failure. A BDI, even after repair, adversely affects the quality of life and can be a financial disaster for the patient and a legal one for the surgeon. As BDI is associated with health & financial disaster, more attention needs to be paid both to prevent and to recognize early such injury. After recognition the patient should be referred to a surgeon experienced in the management of such injuries to avoid further complications.
Journal of Surgical Sciences (2019) Vol. 23 (1) : 33-36
Wire Guided Wide Local Excision of Clinically Undetectable Breast Cancer - Initial Experience in Bangladesh
Authors: Mubin Samia , Hussain Jahangir , Pervez Syed Jamal , Bhowmik Biswajit , Ahmed Saif Uddin 
Published: November 2020

Background: With the rise of awareness of breast cancer and better screening mammography, there are increasing number of breast cancers detected before becoming clinically evident. These cancers are mostly treated by wide local excision under guidance of a wire which is put with mammogram and/or USG. In Bangladesh this procedure has never been done. We started it in Surgical Oncology Division in BSMMU with the collaboration of Department of Radiology.
Methods: We have performed the procedure on 7 patients within 19 months. All of them had USG and mammography detected small lesions. The average size being 7.24mm. From needle biopsy 3 cases showed suspicious cytology, 4 had IDCC, and 1 had DCIS. Wire was put in all cases under USG guidance. Wire Guided Wide Local Excision was performed in all cases. $ patients underwent SLNB.
Results: The age range was between 26 to 55 years with the average age of 43.86 years. 4 of them being post-menopausal. One case came benign. Other were malignant with clear margins. One case had close margin, which was later re-excised. All cases were sent for adjuvant therapy. Histopathology showed 4 patients of invasive ductal carcinoma, 1 patient each of invasive lobular carcinoma, DCIS and 1 being benign.
Conclusion: This well-established procedure can be performed in Bangladesh to meet the goal of ensuring adequate treatment and cosmesis of the patients with impalpable cancer, amidst constrained facilities.
Journal of Surgical Sciences (2019) Vol. 23(2): 81-86
Comparison between Scissors and Electrocautery in Seroma Formation Following Modified Radical Mastectomy (MRM)
Authors: Zim Hasnat Zaman , Hossain SM Amjad , Alam Abul Bashar Mohammad Khurshid , Uddin Samia Shihab 
Published: November 2020

Background and Objective: Seroma is encountered as the commonest complication after mastectomy. Though various factors are suspected in causation of seroma, in this prospective study we tried to evaluate role of two different surgical technique of MRM in causation of seroma formation.
Materials and Methods: In this observational comparative study, a total 90 patient of early breast carcinoma who had undergone Modified Radical Mastectomy (MRM) in 3 tertiary care hospitals of Dhaka were divided into 2 groups. In Group A, we used electrocautery for raising the skin flap and axillary dissection while in Group B we used curved Metzenbaum scissors to raise the skin flap along with aid of suture ligation for axillary dissection. Incidence of seroma formation was compared in both the groups.
Results: Incidence of seroma was significantly higher with use of electrocautery. Results in both the groups were compared by Chi-square method, and statistically significant difference in incidence of seroma formation was found between two groups.
Conclusion: Breast surgery, as MRM does not support injudicious use of electrocautery.
Journal of Surgical Sciences (2019) Vol. 23(2): 87-89
Embryonal Rhabdomyosarcoma of the Testis
Authors: Rahman Ayesha , Alam SM Syeed Ul , Sultana Salma 
Published: November 2020

Rhabdomyosarcoma (RMS), arising from mesenchymal cells, is the most common soft tissue tumour in children and accounts for up to half of all sarcomas. We present a case of a 15 year old male presented with gradually increasing right sided scrotal swelling for last one year. The patient was later diagnosed as right testicular malignancy with metastasis in abdominal lymph nodes and lungs. Inguinal orchidectomy was performed and final histopathological diagnosis was embryonal rhabdomyosarcoma of right testis.
Journal of Surgical Sciences (2019) Vol. 23(2): 98-99
Manejo periodontal y protésico en sonrisa gingival
Authors: Machaca Uchasara Richard Williams 
Published: November 2020

Los tratamientos de la sonrisa gingival tienen como finalidad reducir la exposición de las encías al sonreír. La causa se debe a uno o varios factores; por tanto, un adecuado diagnóstico es primordial para conseguir el mejor resultado. En este artículo, se reporta un caso clínico que tiene como objetivo presentar el manejo estético periodontal y protésico de un caso de sonrisa gingival con presencia de diastemas y alteraciones en forma. Las herramientas utilizadas para la predictibilidad de la sonrisa fueron un diseño digital y mock up. Los resultados obtenidos fueron estéticos, funcionales y satisfactorios para el paciente.
Actualidad de los cementos reparadores endodónticos: MTA y biodentine
Authors: Peñaloza De La Torre Ulises Massino , Calizaya Laquise Naysha 
Published: November 2020

Este artículo de revisión bibliográfica tuvo por objetivo presentar el material con mejores propiedades clínicas para realizar recubrimiento pulpar directo. En la actualidad, es de mucho interés e importancia mantener la vitalidad pulpar de los dientes; consecuentemente, se necesitan materiales odontológicos adecuados que posean propiedades que estimulen o que por lo menos no interfieran en la formación del puente dentinario en las lesiones pulpares. Por un lado, El MTA es un material que ha ido mejorando sus propiedades físico – mecánicas. Por otro lado, el biodentine es un material relativamente nuevo usado como material de recubrimiento pulpar que posee propiedades similares al MTA, pero que tiene la ventaja de poseer un tiempo de fraguado más corto y mejor resistencia mecánica.
Associations of Platelet Count with Inflammation and Response to Anti-TNF-α Therapy in Patients with Ankylosing Spondylitis
Authors: Qian Hongyan , Chen Rongjuan , Wang Bin , Yuan Xiaoqing , Chen Shiju , Liu Yuan , Shi Guixiu 
Published: November 2020

Background: Increased platelet count has been reported in ankylosing spondylitis (AS) patients, but its clinical significance is still largely elusive. The objective of this study was to evaluate the clinical role of platelet count in AS patients, especially its impact on treatment outcomes.Methods: A case-control study containing 35 AS patients receiving anti-tumor necrosis factor-α (anti-TNF-α) therapy and 45 healthy controls was performed, and AS patients were followed at least 6 months after anti-TNF-α therapy. A systematic review and meta-analysis of studies containing relevant data on outcomes of interest was also performed.Results: AS patients had significantly higher platelet count than controls (p = 0.0001), and the significantly increased platelet count in AS patients was confirmed in a meta-analysis of 14 studies involving 1,223 AS patients and 913 controls (mean difference = 39.61, 95% CI 27.89–51.34, p &lt; 0.001). Besides, platelet count was significantly correlated with ESR (p &lt; 0.001) and was moderately correlated with ASDAS-CRP score (p = 0.002). Moreover, anti-TNF-α therapy could reduce platelet count in AS patients at the first month and the effect was maintained through the treatment duration. In the prospective follow-up study of those 35 AS patients, those responders to anti-TNF-α therapy had significantly lower platelet count than nonresponders (p = 0.015). Logistic regression analysis suggested that lower platelet count was associated with higher possibility of achieving good response to anti-TNF-α therapy in AS patients (odds ratio = 2.26; 95% CI = 1.06–4.82; p = 0.035).Conclusion: This study suggested that platelet count was associated with inflammation severity and treatment outcomes in AS patients, and elevated platelet count was a promising biomarker of poorer response to anti-TNF-α therapy. The findings above need to be validated in more future studies.
Celebrex Adjuvant Therapy on Coronavirus Disease 2019: An Experimental Study
Authors: Hong Wenxin , Chen Yan , You Kai , Tan Shenglin , Wu Feima , Tao Jiawang , Chen Xudan , Zhang Jiaye , Xiong Yue , Yuan Fang , Yang Zhen , Chen Tingting , Chen Xinwen , Peng Ping , Tai Qiang , Wang Jian , Zhang Fuchun , Li Yin-Xiong 
Published: November 2020

Background:The pandemic of coronavirus disease 2019 (COVID-19) resulted in grave morbidity and mortality worldwide. There is currently no effective drug to cure COVID-19. Based on analyses of available data, we deduced that excessive prostaglandin E2(PGE2) produced by cyclooxygenase-2 was a key pathological event of COVID-19.Methods:A prospective clinical study was conducted in one hospital for COVID-19 treatment with Celebrex to suppress the excessive PGE2production. A total of 44 COVID-19 cases were enrolled, 37 cases in the experimental group received Celebrex as adjuvant (full dose: 0.2 g,bid; half dose: 0.2 g,qd) for 7–14 days, and the dosage and duration was adjusted for individuals, while seven cases in the control group received the standard therapy. The clinical outcomes were evaluated by measuring the urine PGE2levels, lab tests, CT scans, vital signs, and other clinical data. The urine PGE2levels were measured by mass spectrometry. The study was registered and can be accessed athttp://www.chictr.org.cn/showproj.aspx?proj=50474.Results:The concentrations of PGE2in urine samples of COVID-19 patients were significantly higher than those of PGE2in urine samples of healthy individuals (mean value: 170 ng/ml vs 18.8 ng/ml,p&lt; 0.01) and positively correlated with the progression of COVID-19. Among those 37 experimental cases, there were 10 cases with age over 60 years (27%, 10/37) and 13 cases (35%, 13/37) with preexisting conditions including cancer, atherosclerosis, and diabetes. Twenty-five cases had full dose, 11 cases with half dose of Celebrex, and one case with ibuprofen. The remission rates in midterm were 100%, 82%, and 57% of the full dose, half dose, and control group, respectively, and the discharged rate was 100% at the endpoint with Celebrex treatment. Celebrex significantly reduced the PGE2levels and promoted recovery of ordinary and severe COVID-19. Furthermore, more complications, severity, and death rate were widely observed and reported in the COVID-19 group of elders and with comorbidities; however, this phenomenon did not appear in this particular Celebrex adjunctive treatment study.Conclusion:This clinical study indicates that Celebrex adjuvant treatment promotes the recovery of all types of COVID-19 and further reduces the mortality rate of elderly and those with comorbidities.
Ambiguitas, Interkulturalitas, Dan Hibriditas Relasional Dalam Relasi Antara Israel Dan Bangsa-Bangsa Lain
Authors: Setio Robert 
Published: November 2020

Abstrak: Artikel ini merupakan analisis terhadap hubungan antara Israel dan bangsa-bangsa lainnya dengan menggunakan pemikiran tentang “liyan.” Dalam masyarakat multikultural kehadiran liyan tidak terhindarkan dan menuntut tanggapan yang sungguh-sungguh. Keadaan ini pada gilirannya akan menciptakan ambiguitas, sebagaimana yang dialami oleh Israel. Penemuan arkeologis akhir-akhir ini membuktikan bahwa hubungan antara Israel dengan bangsa-bangsa lain ternyata tidak seperti yang dilukiskan oleh Alkitab. Israel bukanlah sebuah bangsa yang pada suatu masa datang ke Kanaan yang sudah berpenduduk, tetapi mereka muncul secara bertahap dari antara bangsa Kanaan sendiri. Maka, Israel memiliki banyak kesamaan dengan bangsa-bangsa lain itu. Pada pihak lain, Israel juga menumbuhkan sebuah ideologi yang lama-kelamaan akan membentuk mereka menjadi sebuah bangsa. Telah disarankan agar hubungan antara Israel dengan bangsa-bangsa lain itu dipandang sebagai hubungan interkultural. Meskipun pandangan itu masuk akal, namun penulis hendak mengajukan cara pandang lain. Cara pandang itu adalah hibriditas relasional. Dalam pandangan ini, Israel dilihat sebagai sebuah bangsa yang bersifat hibrid, namun bukan dalam arti yang statis. Hibriditas di sini dipandang sebagai sebuah keadaan yang menuntut tanggapan aktif. Dengan kata lain, kesamaan dan perbedaan antara Israel dengan bangsa-bangsa lainnya tidak boleh dianggap sebagai sebuah kondisi yang sudah jadi melainkan terus-menerus dalam proses pembentukan.
Kata-kata kunci: Liyan, ambiguitas, budaya, interkultural, agama, kesamaan, perbedaan, hibriditas relasional.

Abstract: This article will analyze the relationship between Israel and other nations using the concept of “the other.” In a multicultural society, the presence of the other is unavoidable and demands a serious response. This, however, creates ambiguity, as experienced by Israel. Recent archeological findings have proven that the relationship between Israel and other nations mentioned in the Bible was unlike the description provided by the Bible. Israel was not a separate nation that came into an already occupied land of Canaan, but rather, it gradually emerged as agroup from within the people of the land. Therefore, it can be expected that this nation shared many similarities with its cohabitants. On the other hand, it also developed a distinctive ideology which over time formed Israel as a separate nation. It has been suggested to consider the relationship between Israel and the others through the lens of interculturality. This article proposes another perspective, that is, a relational hybridity. From this perspective, Israel is seen as a hybrid nation. The hybridity is understood as a state of life, but, as one that always demands an active response. In other words, it is a process continously evolving.
Keywords: The other, ambiguity, intercultural, religion, similarity, difference, hybridity, relational
PENGARUH PENAMBAHAN ASAM BORAT (H3BO3) TERHADAP HASIL KARAKTERISASI NANOKRISTAL TiO2
Authors: Putama Mursal Iin Lidia 
Published: November 2020

ABSTRAK
Telah dilakukan elektrodeposisi lapisan tipis nanokristal TiO2 dengan menggunakan larutan TiCl4 1,5 M. Karakterisasi SEM dan XRD yang digunakan mengindikasi terbentuknya nanokristal TiO2. Struktur Kristal TiO2 optimal didapat pada lapisan tipis TiO2 yang dielektrodeposisi dengan penambahan asam borat (H3BO3). Hasil SEM menunjukkan bahwa penggunaan CTAB menghasilkan morfologi permukaan yang merata, ukuran butir yang seragam dan terdistribusi hampir merata.

Kata kunci: Elektrodeposisi, asam borat (H3BO3), lapisan Tipis TiO2

ABSTRACT
TiO2 thin film nanocrytal was successfully prepared by electrodeposition method from TiCl4 solution 1,5 M. SEM and XRD characterization of electrodeposited films indicates the formation of TiO2 nanocrystal. The result showed that the optimal structure of TiO2 nanocrystal has been achieved by TiO2 thin film with borac acid (H3BO3). The optimal morphology was obtained by H3BO3 addition. It caused by the grain morphology showed homogenous morphology, grain size, and evenly distributed.
Keywords: Electrodeposition, borac acid (H3BO3),TiO2 nanocrystal
ANALISIS HUBUNGAN FAKTOR RISIKO DENGAN KEJADIAN INTERAKSI OBAT POTENSIAL PASIEN GERIATRI DI RUMAH SAKIT SWASTA YOGYAKARTA
Authors: Arfania Maya 
Published: November 2020

Abstrak
Dewasa ini populasi di Indonesia meningkat dengan pesat. Diprediksi Indonesia akan menduduki 10 besar tertinggi yang memiliki populasi berusia lebih dari 60 tahun, yaitu sebesar 54 per 1000 orang pada tahun 1980 dan 76 per 1000 orang pada tahun 2000. Kemungkinan proporsi lanjut usia akan mencapai 9,8% dari total populasi pada tahun 2010, bahkan peningkatannya dapat mencapai 3,7% antara tahun 2010 sampai 2020.
Penelitian ini adalah penelitian cross sectional, dimana pengambilan sampel dilakukan secara purposive random sampling. Jumlah sampel yang digunakan adalah sebesar 100 lembar resep. Setelah dilakukan analisis dengan menggunakan chi square diketahui bahwa dalam peneltiian ini, jenis kelamin dan jumlah obat bukanlah menjadi faktor risiko dari potensi terjadinya interaksi obat.
Kata kunci : geriatri, interaksi obat, penyakit kronis

Abstract

The population in Indonesia was increase rapidly nowadays. It is been predicted Indonesia will occupy the highest top 10 who has population over 60 years, wich is equal to 54 per 1000 people in 1980 and 76 per 1000 people in 2000. Itâ€™s possible that the proportion of elderly will reach 9,8% of total population in 2010, even the increase can reach 3,7% between 2010 and 2020. This study was a cross-sectional study, where the sampling was done by purposive random sampling. The number of samples is 100 recipes. After analyzed usig chi square, it was found that in this study, gender and the number of drugs were not the risk factor of potential drug interactions.

Keywords: geriatri, drug interaction, chronic disease