bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mental disorders in neurological diseases. Can symptoms of bipolar disorder be the first manifestation of X-linked adenoleukodystrophy? A case report
Authors: Trela Wiktor , Sieńko Cezary , Futyma-Jędrzejewska Małgorzata , Masternak Sebastian , Karakuła-Juchnowicz Hanna 
Published: October 2020

Abstract

Background: X-linked adrenoleukodystrophy (X-ALD) is an inherited metabolic disease which causes demyelination of the white matter of the brain. The symptoms include mental impairment, progressive paresis, impaired motor coordination, and epileptic seizures. Diagnosis is established mainly by genetic testing. Currently, the recommended treatment is haematopoietic stem cell transplantation (HSCT).

Goal: The aim of the study was to present the case of a patient suffering from X-ALD, who developed symptoms of bipolar disorder in the initial phase of the disease prior to the onset of characteristic neurological symptoms.

Case presentation: In 2015, a 33-year-old patient was admitted to a psychiatric department due to aggressive behaviour he showed towards his wife and other family members. He had been treated for a depressive episode in 2005, and for a manic episode without psychotic symptoms earlier in 2015. During the successive psychiatric hospitalizations, in addition to psychopathological symptoms, the patient had been observed to have neurological symptoms, which included progressive paraparesis and ataxia. In 2018, based on imaging and genetic tests, the patient was diagnosed with X-ALD. The patient’s condition gradually deteriorated; with time, he was unable to move on his own. During a hospital stay in 2019, he was transferred to an internal medicine department due to a progressive urinary tract infection, which, however, could not be controlled, and the patient died.

Conclusions:

1. X-ALD is a rare metabolic illness. In the early stages of the disease, various psychopathological symptoms, including affective disorders, are observed.
2. Early initiation of adequate treatment increases the chances of extending the patient’s life.
3. In the present case, the patient did not die due to the underlying disease, but due to causes typical of bed-bound patients, i.e. complications of progressing infection.
An Assessment of Sustainability of Rural Areas of Upper Beas Valley, Himachal Pradesh, India
Authors: Jolli Virat 
Published: October 2020

Summary

Subject and purpose of work: The study aims to assess the sustainability of rural areas of Western Himalayas during the year 2019.

Materials and methods: A questionnaire-based survey was conducted in upper Beas Valley of Himachal Pradesh. A total of 101 individuals were interviewed and the questionnaire was filled by the surveyor.

Results: Survey showed that high level of unemployment prevailed in the region with minimal monthly income. However, they engaged in agriculture and allied activities along with collection of non-timber forest products (NTFPs) to supplement their incomes. The proximity to protected areas led to frequent encounter with wildlife and such encounters increased after the commencement of Hydro Power Projects. Respondents believed that construction HPPs and expansion road network in the region has increased the occurrence of landslides; and many of them had lost their cultivated land due to landslides.

Conclusions: The study showed rural areas of upper Beas Valley were moderately unsustainable.
Savings and Migration Capital of Households: World Experience and Domestic Realities
Authors: Kluchnyk Liliya , Davymuka Stepan 
Published: October 2020

Summary

Subject and purpose of work: The subject of the paper is the formation of household savings in Ukraine and their sources of aggregate household incomes, with particular attention to the Ukrainian labor migration. It is an important source of foreign exchange earnings in the form of remittances, which help improve the welfare of population and ensure economic growth in the country.
The purpose of the paper is to research and determine major trends of the development of households’ financial resources, to examine the foreign experience of forming and use of residents’ savings and to determine the ways it can be applied in Ukraine, and to analyze the main trends of state policy in the regulation of labor migrants’ remittances.

Materials and methods: The author of this paper analyzed the literature on the subject and performed desk research using data from reports and studies published by EU statistics (Euro stat Statistics) and GUS (Statistics Poland), statistical yearbooks of Europe; WDR reports (Global Financial Development Report 2019/2020) and NBU (Official website of the National Bank of Ukraine).

Results: The author’s research has shown that the process of saving is quite popular for European people is quite popular. Accordingly, in 2019, the residents of Poland, Hungary and Romania were the most frugal – 82%, 84% and 85%. Further attitudes towards savings are the following: Turks (77%), Ukrainians (76%), Croats (75%), Serbs (72%), Germans (73%), while savings are slightly less important for Austrians (70%), Slovaks (67%), Czechs (66%), and Montenegrins (59%). This savings situation has clearly demonstrated the power of effective household decisions for overall political and economic activity in Europe. Finally, the migration capital of Ukraine has a “shadow character” due to, first of all, the desire to minimize the costs of transferring funds home through official channels, as well as distrust of the banking sector in Ukraine.

Conclusions: To increase the efficiency of the formation and use of household savings in Ukraine, it is necessary to increase the interest of citizens in savings by partially or completely exempting from taxation the income directed to accumulation and create the conditions necessary for the implementation of new banking, insurance, and other types of financial services.
Cooperation for Renewal of Local Cultural Heritage in Rural Communities: Case Study of the Night of Legends in Latvia
Authors: Paula Līga , Kaufmane Dace 
Published: October 2020

Abstract
The aim of the paper is to describe the phenomenon of the Night of Legends in Latvia particularly focusing on the case of manors in Jelgava county. This event aims to preserve and promote local cultural heritage by active involvement of local community members and visitors (individuals, amateur groups, local businesses, schools, etc.). Thematic activities in manors and palaces are targeted to raise interest and cooperation, what in turn extends the tourist season. The event is organized by the Latvian Association of Castles, Palaces and Manors. The paper includes an analysis of the event’s offer in the context of preservation of cultural heritage as well as interviews with tourism specialists from Jelgava county, particularly involved in organizing the Night of Legends.
Branding of Cultural Tourism Objects of the United Territorial Communities of the Southern Megaregion of Ukraine
Authors: Pavlov Oleksandr , Pavlova Tatiana , Pavlova Iryna 
Published: October 2020

AbstractThe process of decentralization of power and governance, which takes place in Ukraine through the voluntary unification of territorial communities, has laid the foundations for reforming the administrative territorial structure and territorial organization of power. Taking into account the state making nature of these transformations in the context of Ukraine’s European integration efforts, the article substantiates theoretical and applied fundamentals of branding of cultural tourism objects of the united territorial communities (UTC), reveals his role in constructing local identity of these social and spatial formations. The methodology of the study covers three main thematic blocks: legal and political foundations of the creation of a UTC; features of UTC branding; conceptualization and classification of brand projects of cultural tourism objects of the UTC. The factors that inhibit the branding process of cultural tourism objects of these communities were identified, conclusions were drawn, and perspective directions for further scientific exploration were outlined.
Transfer Learning Methods as a New Approach in Computer Vision Tasks with Small Datasets
Authors: Brodzicki Andrzej , Piekarski Michal , Kucharski Dariusz , Jaworek-Korjakowska Joanna , Gorgon Marek 
Published: October 2020

Abstract
Deep learning methods, used in machine vision challenges, often face the problem of the amount and quality of data. To address this issue, we investigate the transfer learning method. In this study, we briefly describe the idea and introduce two main strategies of transfer learning. We also present the widely-used neural network models, that in recent years performed best in ImageNet classification challenges. Furthermore, we shortly describe three different experiments from computer vision field, that confirm the developed algorithms ability to classify images with overall accuracy 87.2-95%. Achieved numbers are state-of-the-art results in melanoma thickness prediction, anomaly detection and Clostridium di cile cytotoxicity classification problems.
A percentile-based estimator for the log-logistic function: Application to forestry
Authors: Ogana Friday Nwabueze 
Published: October 2020

Abstract
Developing a simplified estimation method without compromising the performance of the distribution is germane to forest modelling. Few estimation methods exist for the Log-Logistic distribution and are relatively complex. A simplified estimator for the Log-Logistic parameters will increase its application in diameter distribution yield systems. Therefore, in this study, a percentile-based estimator was applied for the Log-Logistic distribution. The Kolmogorov-Smirnov, Anderson-Darling and Cramer-von Mises statistics were used to evaluate the method in two natural forest stands and two monospecific plantations of Gmelina arborea Roxb. and Tectona grandis Linn. f. in Nigeria. The parameter recovery model (PRM) and parameter prediction model (PPM) were used to predict the diameter distributions of independent stands of G. arborea and T. grandis. The results showed that the percentile estimator did not compromise the quality of fits of the Log-Logistic function across the four forest stands and are comparable to the maximum likelihood estimator. The 25th and 75th, and 40th and 80th were the best sample percentiles for the estimator. The predicted diameter distributions of G. arborea and T. grandis stands from the PRM and PPM were reasonable and compare well with the observed distribution. Thus, either of the models can be incorporated into the growth and yield system of forest stand management.
The Formation of Land Conservation Principles as the Framework for the Implementation of the Concept of Sustainable Development of Society
Authors: Abaikyzy Moldir , Yerkinbayeva Lazzat K. , Aidarkhanova Kulyash N. , Aigarinova Gulnar T. , Baimbetov Nurzhan S. 
Published: October 2020

Abstract
The interest in the experience of legislative solutions to problems connected with the design and development of legal institutions in environmental protection in foreign countries, at first glance, is not directly related to the study of the laws of functioning and development of this legal institution. The relevance of the study is determined by the fact that such an interest appears as rather justified and even logical, if one is to proceed, firstly, from general ideas about the development of land legislation in the context of globalisation, and secondly, if one is to consider the desire of countries to more widely implement global and European standards of environmental policies and rights and approaches to environmental protection in general. The purpose of this article is determined by the identification the main problems of land protection legislation in the field of and form on their basis the effective system of environmental regulation, combining administrative and legislative instruments with economic, regulatory and market mechanisms. Analysis of international legal acts is used as the leading research method. It was determined that the positive experience in foreign countries related to the legal regulation of relations in legal protection of the environment allows transferring the theoretical ideas about the legal structures existing in other countries to the practical plane, which, in turn, allow to optimally regulate the appropriate circle of public relations, taking into consideration the relevant historical traditions, the internal structure of national legislation, the features of the development of environmental legislation of the respective country. The concept of protecting land from pollution by hazardous substances and ways of improving and adapting legislation in the field of waste management were proposed. The practical significance of the study is determined by the need to integrate the land legislation industry into national environmental legislation.
Suppression of inflammatory cytokines expression with bitter melon (Momordica charantia) in TNBS-instigated ulcerative colitis
Authors: Semiz Asli , Ozgun Acar Ozden , Cetin Hulya , Semiz Gurkan , Sen Alaattin 
Published: October 2020

Abstract

Background and Objective
This study was aimed to elucidate the molecular mechanism of Momordica charantia (MCh), along with a standard drug prednisolone, in a rat model of colitis induced by trinitrobenzene sulfonic acid (TNBS).

Methods
After the induction of the experimental colitis, the animals were treated with MCh (4 g/kg/day) for 14 consecutive days by intragastric gavage. The colonic tissue expression levels of C-C motif chemokine ligand 17 (CCL-17), interleukin (IL)-1β, IL-6, IL-23, interferon-γ (IFN-γ), nuclear factor kappa B (NF-kB), and tumor necrosis factor-α (TNF-α), were determined at both mRNA and protein levels to estimate the effect of MCh. Besides, colonic specimens were analyzed histopathologically after staining with hematoxylin and eosin.

Results
The body weights from TNBS-instigated colitis rats were found to be significantly lower than untreated animals. Also, the IFN-γ, IL-1β, IL-6, Il-23, TNF-α, CCL-17, and NF-kB mRNA and protein levels were increased significantly from 1.86-4.91-fold and 1.46-5.50-fold, respectively, in the TNBS-instigated colitis group as compared to the control. Both the MCh and prednisolone treatment significantly reduced the bodyweight loss. It also restored the induced colonic tissue levels of IL-1β, IL-6, IFN-γ, and TNF-α to normal levels seen in untreated animals. These results were also supported with the histochemical staining of the colonic tissues from both control and treated animals.

Conclusion
The presented data strongly suggests that MCh has the anti-inflammatory effect that might be modulated through vitamin D metabolism. It is the right candidate for the treatment of UC as an alternative and complementary therapeutics.
Usage of Laryngeal Mask Airway Devices in Veterinary Medicine
Authors: Vidricková Petra , Boldižár Martin 
Published: October 2020

Abstract
Providing a secure airway management during general anesthesia could be problematic in some medical cases, especially when there is a risk of regurgitation and aspiration of the gastric content due to increased intragastric pressure. The current study aimed to test the applicability of two types of LMA in several animal species and to compare its effectiveness to the endotracheal intubation method in securing sealed airway respiration as an alternative to using endotracheal tubes. The study was conducted in dogs (n=33), cats (n=9), swine (n=9), rabbits (n=5), sheep (n=7) and roe deer (n=1). One or both types of laryngeal masks were used for each animal species: LMA Classic™-cLMA and LMA ProSeal™-PLMA. The assessment of each laryngeal mask was performed by determining the insertion technique, the possibilities of first-attempt insertion and malposition, the compliance with various animal species, ventilation time, cuff pressure, and sealing capacity. The highest LMA size compatility in dogs (23,87±14,30 kg) was size-3 in six and size-4 in forteen subjects; In swine (43,22±12,32 kg), size-4; In rabbits (3,84±0,36 kg) size-1; and in sheep (48,29±4,65 kg) size-3 and size-4. Ventilation time was highest in swine and roe deer (121,11±42,85 min and 300,00 min, respectively) and lowest in cat (28,33±16,96 min). First-attempt LMA insertion success was lowest in rabbits (60%), and highest in sheep and roe deer (100%). Malposition was with highest rate in rabbits (40%) and lowest in cat, sheep and roe deer (0%). Gastric reflux was most frequently observed in sheep (71,4%) and roe deer (100%). The usage of LMA in the veterinary anesthetic practice significantly improves airway management in animals during general anesthesia. The inflated LMA cuff does not prevent its disposition. Therefore, both the drain and respiratory tubes must be fixed. The usage of LMA in rabbits was associated with higher incidence of malposition and other complications. Our findings suggest that LMA designed for humans can be used for airway management in veterinary medicine.
Modification of the Standard 7-Day Ovsynch Protocol to Increase the Luteolytic and Synchronization Risks in Dairy Cows
Authors: Atanasov Branko , Adamov Nikola , Celeska Irena , Ilievska Ksenija , Angjelovski Branko , Trbogazov Zvonko , Davkov Filip , Dovenski Toni , Opsomer Geert , Stevenson Jeffrey 
Published: October 2020

Abstract
We hypothesized that a single dose of PGF2α belatedly injected on day 8 after GnRH-1 in cows receiving a 7-day Ovsynch-56 protocol (GnRH – 7 days – PGF2α – 56h – GnRH – 16h – timed AI) will increase the proportion of cows with complete luteolysis. At day 35±3 postpartum, 70 lactating Holstein cows from one herd were scored for body condition and pre-synchronized with PGF2α and GnRH (3 days apart) and 7 days later submitted to an Ovsynch-56 protocol for first AI after random assignment to two treatments: (1) OV-7 (n=35) with an injection of PGF2α either on day 7; or (2) OV-8 (n=35) on day 8 after G1, respectively. Blood was collected before the first PGF2α, at day 7 and day 8 in OV-7 and OV-8, respectively, at AI and at 7 days after AI to assess progesterone concentration. Ten cows were classified as acyclic and were excluded from the analysis resulting in 60 cows (OV-8, n=27; OV-7, n=33). In total, more (P=0.01) OV-8 cows and more (P=0.04) primiparous OV-8 cows had complete luteolysis compared with their OV-7 herd mates. In addition, more (P=0.008) OV-8 cows with BCS<2.75 had complete luteolysis compared with their OV-7 herd mates, whereas no difference was observed between treatments among cows with BCS ≥2.75. In conclusion, delaying the application of PGF2α by 1 day reduced the percentage of primiparous cows and cows with poorer BCS having incomplete luteal regression at the time of AI.
Sero-Prevalence of Bovine Leukemia Virus Infection in Kosovo Cattle
Authors: Gjinovci Valdet , Cana Armend , Alishani Mentor , Mehmetukaj Dafina , Taylor Nick , Honhold Naomi 
Published: October 2020

Abstract
A cross-sectional survey was conducted in Kosovo to determine the presence and prevalence of bovine leukemia virus antibodies in cattle. A total of 5,051 serum samples from 315 villages were collected during 2016. Samples were tested using commercial indirect enzyme-linked immunosorbent assay. At least one sero-positive animal was found in 55 (17.5%) of the villages sampled, of which 23 had more than one sero-positive detected. Overall individual sero-prevalence, corrected for geographic distribution of samples, was found to be 2.26% (95% c.i. 1.62% to 3.04%). There were no statistically significant associations between serological status and herd size or age of animal, although sero-prevalence in 5-year-old cattle was higher than in the other ages. There was a statistical significant heterogeneity in sero-prevalence between different geographic zones of Kosovo (chi-square value = 20.68 (4 d.f.); (p=0.0004). Pairwise comparisons showed that sero-prevalence in the south was significantly higher than in the east and in the north and sero-prevalence in the west was significantly higher than in the north. The 3.11% aggregated sero-prevalence for the two highest sero-prevalence zones, south and west, was significantly higher than the 1.57% aggregated sero-prevalence for the remaining zones, centre, east and north (Fisher exact p-value (2-tail) = 0.0004). The reason for higher prevalence in the south and west of Kosovo is uncertain. These results may serve to enrich the information of bovine leukemia virus distribution in the region, as well as a starting point for the future control and eradication strategy in Kosovo.
Transformation of the identity of a region: Theory and the empirical case of the perceptual regions of Bohemia and Moravia, Czech Republic
Authors: Marek Petr 
Published: October 2020

Abstract
By using the concept of perceptual region – an essential part of the identity of a region and a part of every person’s mental map – this paper demonstrates a way to examine the understudied transformation of (the identity of) a region and, specifically, its territorial shape (boundaries). This concept effectively fuses the “institutionalisation of regions” theory and the methodologies of behavioural geography. This case study of the perceptual regions of Bohemia and Moravia shows how and why these historical regions and their boundary/boundaries developed, after a significant deinstitutionalisation by splitting into smaller regions in an administrative reform. Many people now perceive the Bohemian-Moravian boundary according to the newly-emerged regional boundaries, which often ignore old (historical) boundaries. Thus, the territorial shape of Bohemia and Moravia is transformed, with the Vysočina Region emerging as one of the new regions to witness the most eroded consciousness concerning these historical regions and their boundaries. The impact of administrative reforms on the perception and thus also the transformation of regions and boundaries is obvious, but the results also suggest that the more radical the administrative changes (in terms of toponyms and boundary mismatches), the fuzzier the collective perceptions of historical boundaries become, as well as peoples’ consciousness of historical regions.
“Surely it will come again…”. Flood threat appraisal, mitigation strategies and protection motivation in Czech communities endangered by floods
Authors: Andráško Ivan , Dolák Klemešová Kamila , Dolák Lukáš , Trojan Jakub , Fiedor David 
Published: October 2020

Abstract
A recent “shift” in flood risk management is associated with putting more emphasis on private mitigation and protection measures, and on shared responsibility. Based on case study research in the South Bohemian municipalities (Czech Republic) endangered by floods, this paper reports floods-related attitudes and actions of local inhabitants. A total of 305 respondents participated in a survey; responses and additional commentaries were examined through qualitative content analysis. Results show that though most of the local residents are aware of the constant threat, a minority of them take up any mitigation measures or have some strategy to handle a flood. Several cognitive biases and non-protective responses, the lack of interest and personal responsibility, perceived costs, as well as the prevailing low perceived importance of floods for the local quality of life, hamper improvements in general preparedness. From the viewpoint of Protection Motivation Theory, neither the locals’ threat appraisal nor their coping appraisal is high enough to sufficiently incentivise them to adopt private mitigation strategies and measures. Flood information seems to be at hand for local residents, who are, however, mostly not interested in using it. Perceived obscurities in handling the financial resources contribute to the prevailing unwillingness to participate financially in flood protection. Differences in perceptions and actions are associated with respondents’ individual characteristics (age, gender, level of education, previous experience with floods). Based on our findings, we discuss several relevant policy implications.