bluuebunny/crossref_metadata_2025_split huggingface dataset:
Merumuskan Ulang Konsep Moralitas: Sumbangan Pemikir Feminis
Authors: Sugiyono Paulus Bagus 
Published: January 2021

The aim of this article is to re-conceptualize the meaning of morality according to the perspective of feminists. This article employed the method of literature review within the qualitative approach. Morality, in the history of western thought, is often related with the concept offered by Immanuel Kant. Human being is perceived to have a sufficient ratio to access the universal morality. Therefore, there is no reason for not following the principles of morality. Nevertheless, feminists argued that the concept offered by Kant does not give a flexible space for the dynamics of contingent things, such as feeling, sensitivity, and inclination. Whereas, these contingent things have given such an influential meaning for the concept of morality. Marilyn Friedman (2000) specifically proposes and explains this point of view in her article entitled “Feminism in Ethics: Conception of Autonomy”. Her approach is thus later shown clearly in the concept of care ethics. Even though, I argue that care ethics would not substitute Kantian ethics, but rather complement it, so that the paradigm of the morality can be seen broader from several perspectives. This entwined paradigm, between Kantian and care ethics, is then can be employed to analyze various social phenomena that occur in our society. Tujuan artikel ini adalah untuk merumuskan ulang konsep mengenai moralitas, terutama ketika mendapatkan sumbangsih pemikiran dari para pemikir feminis. Metode yang digunakan dalam penelitian ini adalah kajian literatur dalam pendekatan kualitatif. Moral, dalam perjalanan panjang sejarah pemikiran barat, identik dengan pemikiran Immanuel Kant dalam sifatnya yang berlaku universal. Untuk mengakses universalitas moral, manusia diandaikan memiliki nalar atau rasionalitas yang cukup. Dengan demikian, sebagai manusia yang otonom secara moral, tidak ada alasan baginya untuk tidak mengikuti prinsip-prinsip moral. Penggunaan nalar tidak memberikan ruang bagi hal-hal yang sifatnya kontingen, seperti perasaan, sensitivitas, dan kecenderungan. Hasil penelitian ini menunjukkan bahwa apa yang disingkirkan oleh etika Kantian tadi diangkat oleh para pemikir feminis. Mereka memberikan sumbangsih pemikirannya tersendiri dalam membangun konsep moralitas. Selain itu, penelitian ini juga menunjukkan bahwa etika kepedulian adalah muara dari pemikiran mengenai moralitas dari para pemikir feminis. Meski demikian, etika kepedulian tidak hadir sebagai substitusi atau pengganti dari etika Kantian, melainkan sebagai komplementer yang menjadikan cakrawala moralitas semakin utuh. Bak dua sisi sepayang sayap, kedua pendekatan moralitas tadi saling menyeimbangkan pemaknaan mengenai apa itu moralitas, terutama untuk menelaah fenomena-fenomena secara sosiologis dalam masyarakat.
Communication et EcoCitoyennete de la Population du District dâ€™Abidjan Face a L'insalubritÃ© Environnementale
Authors: Liliane Kouassi Amoin 
Published: January 2021

Lâ€™insalubritÃ© environnementale que subit aujourdâ€™hui le district dâ€™Abidjan est une rÃ©alitÃ© qui rÃ©sulte en grande partie des actions posÃ©es par lâ€™homme sur son espace de vie. Les objectifs de cette recherche Ã©taient dans un premier temps dâ€™identifier les causes liÃ©es au comportement de la population et dans un second temps de proposer des stratÃ©gies communicationnelles dans le but de lâ€™amener Ã avoir des gestes Ã©co-citoyens. Une Ã©tude a Ã©tÃ© menÃ©e dans la commune de Cocody, Yopougon et Abobo. La collecte de donnÃ©es de ce travail a Ã©tÃ© possible grÃ¢ce Ã une observation non participante, une recherche documentaire et Ã un entretien directif sur quarante-deux (42) personnes. De cette Ã©tude, il ressort que le manque dâ€™informations ou de connaissances sur la gestion de lâ€™environnement Ã©tait Ã la base du mauvais comportement de la population. Cependant, elle nâ€™est pas la seule raison; les normes subjectives, le laxisme dâ€™un type de population, la projection psychologique que certaines personnes font sur les autres sont aussi des facteurs qui amÃ¨nent cette population Ã mal agir. De ce fait, un changement de comportement sâ€™avÃ¨re nÃ©cessaire Ã travers des stratÃ©gies comme lâ€™Information, lâ€™Education, la Communication (IEC), la communication participative et la communication persuasive.
The environmental insalubrity that the district of Abidjan undergoes today is a reality which results in large part from the actions taken by man on his living space. The objectives of this research were firstly to identify the causes linked to the behavior of the population and secondly to propose communication strategies in order to get them to take eco-citizen actions. A study was carried out in the towns of Cocody, Yopougon and Abobo. Data collection for this work was made possible through non-participant observation, documentary research and a structured interview with forty-two (42) people. From this study, it emerges that the lack of information or knowledge on environmental management was at the root of the poor behavior of the population. However, she is not the only reason; subjective norms, the laxity of a type of population, the psychological projection that certain people make on others are also factors which lead this population to act badly. Therefore, behavior change is necessary through strategies such as Information, Education, Communication (IEC), Participatory Communication and Persuasive Communication.
Structure du Budget Dâ€™investissements Publics de Sante Dans la Region du Centre/Cameroun (2013-2017)
Authors: Tsamo Louis Merlin , Kaptchouang Lionel Djibie , Mougoue BenoÃ®t , Tsalefac Maurice 
Published: January 2021

Entre 2013 et 2017, le budget dâ€™investissements publics du MinistÃ¨re de la santÃ© publique allouÃ© Ã la rÃ©gion du Centre est passÃ© de 2 093 800 000 francs CFA Ã 17 903 270 000. Le montant cumulÃ© de ces investissements publics en santÃ© dans la rÃ©gion Ã©tait de 37 185 970 000 francs CFA. En dÃ©pit de ces investissements massifs, les populations de la rÃ©gion en gÃ©nÃ©ral et celles des zones rurales en particulier Ã©prouvent des difficultÃ©s pour accÃ©der aux soins et services de santÃ©. Lâ€™objectif de cet article est de cartographier le type de projets inscrits au budget dâ€™investissements publics en santÃ© allouÃ©s Ã la rÃ©gion du Centre afin dâ€™Ã©valuer sâ€™ils sont de nature Ã amÃ©liorer lâ€™offre de soins et services de santÃ© pour les populations. Lâ€™analyse des allocations de projets rÃ©vÃ¨le quâ€™en termes dâ€™effectif, le nombre et le type de projets allouÃ©s Ã la rÃ©gion du Centre pourraient concourir Ã amÃ©liorer lâ€™offre de soins en son sein. Toutefois, les volumes financiers dÃ©diÃ©s Ã ces investissements restent insuffisants, ce qui explique en partie le fait que les populations de cette rÃ©gion Ã©prouvent des difficultÃ©s Ã accÃ©der aux soins et services de santÃ©.
Between 2013 and 2017, the public investment budget of the Ministry of Public Health allocated to the Central region increased from 2,093,800,000 CFA francs to 17,903,270,000 CFA francs. The cumulative amount of these public investments in health in the region was 37,185,970,000 CFA francs. Despite these massive investments, the region's populations in general and those in rural areas in particular are facing difficulties in accessing health care and services. The objective of this article is to map the type of projects included in the public health investment budget allocated to the Central region in order to assess whether they are likely to improve the provision of health care and services for the populations. The analysis of project allocations reveals that in terms of staffing levels, the number and type of projects allocated to the Centre could help improve the supply of care within the Centre. However, the financial volumes dedicated to these investments remain insufficient, which partly explains the fact that the region's populations are experiencing difficulties in accessing health care and services.
Peran Kepala Sekolah sebagai Manajer dalam Meningkatkan Partisipasi Masyarakat di SD Islam Az-Zahrah
Authors: Siregar Nursamsiah 
Published: January 2021

Penelitian ini bertujuan untuk mengungkapkan kepala sekolah sebagai manajer dalam meningkatkan partisipasi masyarakat, partisipasi masyarakat terhadap sekolah dan faktor-faktor yang mendukung dan menghambat kepala sekolah sebagai manajer dalam meningkatkan partisipasi masyarakat di SD Islam Az-Zahrah Palembang. Penelitian ini termasuk penelitian lapangan (field research) yaitu penelitian dengan cara langsung ke tempat penelitian untuk mengamati dan terlibat langsung dengan objek penelitiannya. Jenis penelitiannya ialah penelitian studi kasus yang bersifat kualitatif dengan logika berfikir induktif, dimana penelitian ini memiliki karakteristik bahwa datanya dinyatakan dalam keadaan sewajarnya. Penelitian ini menggunakan metode kualitatif, yaitu dengan metode observasi, wawancara, dan dokumentasi. Hasil penelitian yaitu (1) kepala sekolah dalam meningkatkan partisipasi melalui delegasi pelayanan, (2) Partisipasi masyarakat terhadap sekolah, baik masyarakat secara umum, maupun melalui komite sekolah dalam memberikan pertimbangan (advisory agency), memberikan dukungan (supporting agency) mengawasi penyelenggaraan pendidikan di sekolah (controlling agency) dan penghubung antara sekolah dengan orangtua siswa (mediator) dapat terlaksana dengan baik, (3) Sementara faktor penghambat dalam meningkatkan partisifasi masyarakat, hususnya orang tua, mereka tidak memiliki waktu banyak untuk ikut ber secara langsung pada setiap kegiatan sekolah.
Survey Study of ESP Learning Needs at the Islamic Religious Education Study Program of Tarbiyah Faculty of IAIN Bengkulu
Authors: Rizal Syamsul , Maryam Maryam 
Published: January 2021

This study aimed to determine the needs of non-English Study Program students. Quantitative and survey methods were applied in this study. A questionnaire through the Graves model analysis consisting of student profile analysis, Target Situation Analysis (TSA), Current Situation Analysis (CSA), and Learning Situation Analysis (LSA) were the instruments used in collecting the data. Participants were the third-semester students of the Islamic Religious Education Study Program at Tarbiyah and Tadris Faculty of IAIN Bengkulu in 2018 to 2019 academic year. In determining the participants, the writers applied a simple random sampling technique. There were 37 students from a total population of 150 students. The data were analyzed using descriptive statistical analysis, namely by calculating percentage (%) and classified data so that the needs of students in learning English could be identified. The findings were (1) the ESP approach was the right approach to be applied in learning English at IAIN Bengkulu based on the students’ age and experience in learning English, (2) the gap between the targeted needs by the campus and the students’ English skills was less, (3) the gap between what students needs and the material in the ESP English textbook was in category desire, and (4) the topic of reading comprehension text was directly related to the study of Islamic Religious Education as a student’s area of ​​expertise.
Chemoproteomics Maps Glycolytic Targetome in Cancer Cells
Authors: Hao Haiping , Tian Yang , Wan Ning , Ding Ming , Shao Chang , Wang Nian , Bao Qiuyu , Lu Wenjie , Hu haiyang , Sun Huiyong , Yang Chenxi , Zhou Kun , Chen Shuai , Wang Guangji , Ye Hui 
Published: January 2021

Abstract
Hyperactivated glycolysis, favoring uncontrolled growth and metastasis by producing essential metabolic intermediates engaging bioenergetics and biosynthesis, is a metabolic hallmark of most cancer cells. Although sporadic information has revealed glycolytic metabolites also possess non-metabolic function as signaling molecules, it remains largely elusive how these metabolites interact with and functionally regulate their binding targets. Here we introduce a Target Responsive Accessibility Profiling (TRAP) approach that measures ligand binding-induced steric hindrance in protein targets via global profiling accessibility changes in reactive lysines, and mapped 913 target candidates and 2,487 interactions for 10 major glycolytic metabolites in cancer cells via TRAP. The elucidated targetome uncovers diverse regulatory modalities of glycolytic metabolites involving the direct perturbation of carbohydrate metabolism enzymes, intervention of transcriptional control, modulation of proteome-level acetylation and protein complex assemblies. The advantages gained from glycolysis by cancer cells are expanded by discovering lactate as a ligand for an orphan transcriptional regulator TRIM 28 that promotes p53 degradation, and by identifying pyruvate acting against a cell apoptosis inducer trichostatin A via attenuating protein acetylation. Lastly, the inhibition of glycolytic key enzymes led to identify an intrinsically active glycolytic intermediate glyceraldehyde 3-phosphate that elicits its cytotoxicity by engaging with ENO1 and MTHFD1. Collectively, the glycolytic targetome depicted by TRAP constitutes a fertile resource for understanding how glycolysis finely tunes metabolism and signaling in support of cancer cells, and fostering the exploitation of glycolytic targetome as promising nodes for anti-cancer therapeutics development.
Using A New Endodontic Tooth Model as an Alternative in Clinical Education Course During the Covid-19 Pandemic
Authors: Yekta-Michael Sareh Said , Färber Christoph Maria , Heinzel Alexander 
Published: January 2021

Abstract
Background The COVID-19 pandemic massively impacts endodontic teaching and a dramatically reduced number of patients is registered in clinical courses. This could be countered with suitable training aids. Based on treatment errors made by students in the last five years of endodontic courses at RWTH Aachen University (Germany), a new artificial root canal treatment model (DRSK RCT) was developed. The model was aimed to be radiopaque and to simulate the tactile feel during instrumentation in a realistic manner. Unlike already existing 3D-printed tooth replicas, the RCT has anatomical root canals with a narrow lumen with its width matching an ISO size 6 endodontic file. Methodology 35 fourth-year students and seven dental demonstrators performed endodontic treatments on both the DRSK RCT and extracted teeth. Students and demonstrators answered a questionnaire on a scale ranging from 1 to 7 (poor to high) for different items (part 1). After the first study, changes in the materials and root canal anatomy were applied to the model. Then, the whole study was repeated and evaluated (part 2). Finally, it was evaluated whether the models could replace patient treatment during the Covid-19 pandemic. Results Ratings by students and dental instructors (5.1 ± 0.4 and 5.3 ± 1.5 [mean ± SD], respectively) in the first study increased after modifications of the DRSK RCT (5.5 ± 0.5 and 6.2 ± 0.8, respectively). Radiographs of the models were excellently assessable. The properties of the DRSK RCT were found to be realistic, thus allowing students to perform a satisfactory simulation of root canal treatment and being rated sufficient in substituting patient treatment during COVID-19 pandemic. Conclusion The analysis suggests that the DRSK RCT has the ability to improve endodontic technique and education. Visible root canals enable students to observe the treatment process. All steps of a regular root canal treatment can be simulated. Further studies are needed to investigate the outcome of treating the first patient after practicing on the DRSK RCT.
Exploring Therapeutic Efficacy of Coriandrum Sativum and Allium Sativum Aggregate in Alloxan-induced Diabetic Mice
Authors: Qamar Shahzad , Butt Mubasher , Anwar Rukhsana , Jabbar Basit 
Published: January 2021

Abstract
Diabetes mellitus (DM) is a global health problem with 422 million individuals around the world suffering from diabetes. Coriandrum sativum and Allium sativum possess numerous bioactive compounds which are of therapeutical significance. This study was undertaken to explore the combined potential of the two herbs in managing diabetes using diabetic albino mice as model. Extracts of both herbs were prepared and were orally administered in 10% Alloxan monohydrate (alloxan) induced diabetic albino mice over 28 days (in four doses with 7 day interval) to determine the optimal therapeutic and lethal doses. Safe dose limit of both extracts was deduced to be below 600 mg/kg (<600 mg/kg). Diabetic mice were given extracts (200 mg/kg and 400 mg/kg) over 56 days at 7 day intervals, and biological parameters were evaluated, at each interval, including Glucose level (mg/dl), HbA1C (%), Hepatic and Renal biomarkers, and Lipid profile. Garlic-coriander combination (at 400 mg/kg) was able to reduce glucose level (i.e.194.5 mg/dl) (P<0.05). Also, it showed a worthwhile effect on biological parameters as well as in Hepatic and renal tissues. Histological examination of hepatic and renal tissues indicated a restoration of normal tissue 26 architecture.
WITHDRAWN: Persistent Uncontrolled Asthma: Long-Term Impact on Physical Activity and Body Composition
Authors: Abdo Mustafa , Waschki Benjamin , Kirsten Anne-Marie , Trinkmann Frederik , Biller Heike , Herzmann Christian , von Mutius Erika , Kopp Matthias , Hansen Gesine , Rabe Klaus. F , Bahmer Thomas , Watz Henrik 
Published: January 2021

Abstract
Rational Asthma, obesity and physical activity (PA) are interrelated. However, longitudinal data with objective PA measures and direct assessment of body composition are still lacking.Objectiveto study the impact of asthma severity and symptom control on PA and body composition.MethodsIn a longitudinal cohort study, we assessed the body composition of 233 asthma patients and 84 healthy controls using bioelectrical impedance analysis. PA (i.e. average daily steps and time of at least moderate activity, steps/min) was measured by accelerometry for one week. Asthma control was assessed by ACT score, ACQ-5 score and history of severe exacerbations. After two years of follow up, we studied changes in physical activity and body composition in relation to asthma control.ResultsPatients with severe asthma had increased fat mass and decreased muscle mass compared to patients with mild-moderate asthma or healthy controls. Both fat mass and muscle mass correlated better with asthma control than the body mass index (BMI). In multivariate regressions adjusted for confounders including asthma severity and corticosteroid therapy, physical activity was an independent predictor of body composition (R2 ≥ 0.61, p < 0.001). Persistent uncontrolled asthma patients (n=64) had lower physical activity at both baseline (6614 steps/118 min) and follow up (6195/115). Despite having stable BMI, they also had significant muscle loss (-1.2%, -0.88 kg, p<0.01) and fat accumulation (+1%, +1.1 kg, p<0.01). By contrast, temporarily uncontrolled or controlled asthma patients had higher physical activity at baseline (8670/156) and follow up (9058/153) with almost unchanged body composition.ConclusionPersistent uncontrolled asthma is associated with sustained physical inactivity and adverse changes in body composition that might be overlooked by relying solely on BMI. Physical activity is an independent predictor of body composition and reliable long-term marker of symptom control.
ISSI2020:An Approach&nbsp;for Obtaining Material Mechanical Properties in&nbsp;Structure Local Region&nbsp;Based on An Accurate Analysis&nbsp;of Micro-Indentation Test
Authors: Xue He , He Jinxuan , Zhang Jianlong , Xue Yuxuan 
Published: January 2021

Abstract
The welding and other hot or cold processing region behavior in important structures is the key characteristics for the structural integrity assessment, it is necessary to accurately derive the material mechanical properties in the failure driving force (such as stress and strain) analysis in the local area. The hot or cold processing would induce the change and the inhomogeneous of the material mechanical properties in the local processing region of the structure, and it is difficult to obtain the precise mechanical properties in these regions by the traditional material tensile test. To accurately obtain actual material mechanical properties in the local region of structures, a micro-indentation test system has been established, which incorporated by a CMT6103 Material Test Device, an indenter displacement sensor and a group of special micro-indenter assemblies are established, and a numerical testing inversion analysis method by using ABAQUS software is also proposed in this paper. Based on above test system and analysis platform, an approach to obtain material mechanical properties in local region of structure is proposed and established. The verification experiment and analysis is performed by using a group of various changed mechanical property of 316L austenitic stainless steel through different cold-work hardening. The investigated results indicate the material mechanical properties and the micro-indentation morphological change have evidently relevance, and the material mechanical parameters, such as the yield stress σ y , the strain hardening exponent n and others could be conveniently and effectively obtained by the proposed approach in this paper.
Contrasting magma compositions between Cu and Au mineralized granodiorite intrusions in the Tongling ore district in South China using apatite chemical composition and Sr-Nd isotopes
Authors: Pan Li-Chuan , Hu Rui-Zhong , Oyebamiji Abiola , Wu Hong-Yuan , Li Jin-Wei , Li Jin-Xiang 
Published: January 2021

Abstract
Identifying magma fertility is an important task in ore genesis research. In this paper, we use apatite chemistry and Sr-Nd isotopes for such a study. The apatite crystals are from four Cretaceous coeval granodiorite intrusions with different styles of hydrothermal mineralization in the Tongling ore district, South China. The selected intrusions are Hucun, Dongguashan, and Xinwuli, which host both porphyry and skarn Cu deposits, and the Chaoshan, which hosts a skarn Au deposit. The abundances of apatite major and trace elements, such as Mn, V, Ce, S, F, Cl, and Cu, together with the whole-rock compositions, are used to decipher the oxidation states, volatile compositions, and Cu fertility of the parental magmas. The apatite Sr-Nd isotope compositions are used as tracers for the magma sources. The results show that: (1) the parental magma of the Au-mineralized intrusion is less oxidized and has higher S-Cl contents than those of the Cu-mineralized intrusions, and (2) the proportion of mantle-derived melt is much higher in the former than in the latter. The results also reveal that the Cumineralized intrusions have highly variable apatite Cu-Cl-S compositions. Specifically, the Xinwuli intrusion has much higher Cu but lower Cl-S contents in apatite than the other two intrusions, indicating that a Cu-rich magma is not universally required for the formation of hydrothermal Cu deposits. This study demonstrates that apatite is a robust petrogenetic and metallogenic indicator for porphyry and skarn-type Cu-Au ore deposits.