bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexual dimorphism and sex ratio bias in the dioecious willowSalix purpureaL
Authors: Gouker Fred E. , Carlson Craig H. , Zou Junzhu , Evans Luke , Crowell Chase R. , Smart Christine D. , DiFazio Stephen P. , Smart Lawrence B. 
Published: April 2020

AbstractPremiseSexual dimorphism in dioecious plant species is often not obvious or is absent. Dioecious species populations also often exhibit deviations from expected sex ratios. Previous studies on members of the Salicaceae family have shown strong, partial, and no sexual dimorphism. Some studies have shown sex-biased ratios in severalSalixspp., however,S. purpureahas never been examined for evidence of sexual dimorphism or for the presence of sex-ratio bias, and therefore a comprehensive phenotypic study is needed to fill this knowledge gap.MethodsThis study examined a suite of morphological, phenological, physiological and wood composition traits from multi-environment and multi-year replicated field trials in a diversity panel of unrelatedS. purpureaaccessions and in full-sib F1and F2families produced through controlled cross pollinations to test for sexual dimorphism and sex ratio bias.Key ResultsSignificant evidence of sexual dimorphism was found in vegetative traits with greater means for many traits in male genotypes compared to females across three populations ofS. purpurea, measured across multiple years that were highly predictive of biomass yield. Male plants exhibited greater nitrogen accumulation under fertilizer amendment as measured by SPAD in the diversity panel, and males showed greater susceptibility to fungal infection byMelampsoraspp in the F2family. There were also consistent female-biased sex ratios in both the F1and F2families.ConclusionsThese results provide the first evidence of sexual dimorphism inS. purpureaand also confirm the prevalence of female-biased sex ratios previously found in otherSalixspecies.
Seqpare: a self-consistent metric of similarity between genomic interval sets
Authors: Feng Selena C. , Sheffield Nathan C. , Feng Jianglin 
Published: April 2020

ABSTRACTSummarySearching genomic interval sets produced by sequencing methods has been widely and routinely performed; however, existing metrics for quantifying similarities among interval sets are inconsistent. Here we introduceSeqpare, a self-consistent and effective metric of similarity and tool for comparing sequences based on their interval sets. With this metric, the similarity of two interval sets is quantified by a single index, the ratio of their effective overlap over the union: an index ofzeroindicates unrelated interval sets, and an index ofonemeans that the interval sets are identical. Analysis and tests confirm the effectiveness and self-consistency of theSeqparemetric.Availabilityhttps://github.com/deepstanding/seqpareContactjf.xtable@gmail.com
The classroom relational environment and children’s early development in preschool
Authors: Nguyen Tutrang , Ansari Arya , Pianta Robert C. , Whittaker Jessica V. , Vitiello Virginia E. , Ruzek Erik 
Published: April 2020

AbstractThe present study considered the ways in which interactional quality in the classroom and teacher–child relationships independently and synergistically shaped the early academic, social‐behavioral, and executive function outcomes of 1,498 preschoolers from low‐income families from a large, culturally, and linguistically diverse county. The findings revealed that children who had closer and less conflictual relationships with their teachers demonstrated greater improvements in all domains of school readiness across the preschool year. Moreover, preschool attendees did not reap the maximum academic benefits from high quality classroom environments unless they also had high‐quality individual relationships with their teachers. Implications for policy and practice are discussed.
The BGOOD experimental setup at ELSA
Authors: Alef S. , Bauer P. , Bayadilov D. , Beck R. , Becker M. , Bella A. , Bieling J. , Böse S. , Braghieri A. , Brinkmann K.-Th. , Cole P. L. , Di Salvo R. , Elsner D. , Fantini A. , Freyermuth O. , Frommberger F. , Gervino G. , Ghio F. , Goertz S. , Gridnev A. , Gutz E. , Hammann D. , Hannappel J. , Hillert W. , Jahn O. , Jahn R. , Johnstone J. R. , Joosten R. , Jude T. C. , Kalinowsky H. , Kleber V. , Klein F. , Kohl K. , Koop K. , Kozlenko N. , Krusche B. , Lapik A. , Sandri P. Levi , Lisin V. , Lopatin I. , Mandaglio G. , Manganaro M. , Messi F. , Messi R. , Moricciani D. , Mushkarenkov A. , Nedorezov V. , Novinskiy D. , Pedroni P. , Polonskiy A. , Reitz B.-E. , Romaniuk M. , Rostomyan T. , Scheluchin G. , Schmieden H. , Stugelev A. , Sumachev V. , Tarakanov V. , Vegna V. , Walther D. , Zaunick H.-G. , Zimmermann T. 
Published: April 2020

AbstractThe BGOOD experiment at the ELSA facility in Bonn has been commissioned within the framework of an international collaboration. The experiment pursues a systematic investigation of non-strange and strange meson photoproduction, in particular t-channel processes at low momentum transfer. The setup uniquely combines a central almost $$4\pi $$4π acceptance BGO crystal calorimeter with a large aperture forward magnetic spectrometer providing excellent detection of both neutral and charged particles, complementary to other setups such as Crystal Barrel, Crystal Ball, LEPS and CLAS.
Deep Learning–Derived High-Level Neuroimaging Features Predict Clinical Outcomes for Large Vessel Occlusion
Authors: Nishi Hidehisa , Oishi Naoya , Ishii Akira , Ono Isao , Ogura Takenori , Sunohara Tadashi , Chihara Hideo , Fukumitsu Ryu , Okawa Masakazu , Yamana Norikazu , Imamura Hirotoshi , Sadamasa Nobutake , Hatano Taketo , Nakahara Ichiro , Sakai Nobuyuki , Miyamoto Susumu 
Published: April 2020

Background and Purpose—
For patients with large vessel occlusion, neuroimaging biomarkers that evaluate the changes in brain tissue are important for determining the indications for mechanical thrombectomy. In this study, we applied deep learning to derive imaging features from pretreatment diffusion-weighted image data and evaluated the ability of these features in predicting clinical outcomes for patients with large vessel occlusion.

Methods—
This multicenter retrospective study included patients with anterior circulation large vessel occlusion treated with mechanical thrombectomy between 2013 and 2018. We designed a 2-output deep learning model based on convolutional neural networks (the convolutional neural network model). This model employed encoder-decoder architecture for the ischemic lesion segmentation, which automatically extracted high-level feature maps in its middle layers, and used its information to predict the clinical outcome. Its performance was internally validated with 5-fold cross-validation, externally validated, and the results compared with those from the standard neuroimaging biomarkers Alberta Stroke Program Early CT Score and ischemic core volume. The prediction target was a good clinical outcome, defined as a modified Rankin Scale score at 90-day follow-up of 0 to 2.

Results—
The derivation cohort included 250 patients, and the validation cohort included 74 patients. The convolutional neural network model showed the highest area under the receiver operating characteristic curve: 0.81±0.06 compared with 0.63±0.05 and 0.64±0.05 for the Alberta Stroke Program Early CT Score and ischemic core volume models, respectively. In the external validation, the area under the curve for the convolutional neural network model was significantly superior to those for the other 2 models.

Conclusions—
Compared with the standard neuroimaging biomarkers, our deep learning model derived a greater amount of prognostic information from pretreatment neuroimaging data. Although a confirmatory prospective evaluation is needed, the high-level imaging features derived by deep learning may offer an effective prognostic imaging biomarker.
Endoscopic combined intrarenal surgery in the prone-split leg position for successful single session removal of an encrusted ureteral stent: a case report
Authors: Wang Daming , Sun Hongliang , Chen Lei , Liu Zhiqi , Zhang Dazhao , Yu Dexin , Ding Demao 
Published: April 2020

Abstract
Background
The most serious complication of ureter stent is long-term retention of ureteral stent and stone formation around the stent.

Case presentation
A 51-year old female patient with left ureteral stent placed 2 years before developed both pyelic and vesical stones on the two ends of the double J was admitted to our hospital. Intravesical lithotripsy, retrograde ureteroscopy, and percutaneous nephrolithotripsy were performed with the patient in the prone split-leg position. All the stones and the ureteral stent were successfully removed in a single session.

Conclusions
Combined endoscopic techniques in the prone split-leg position can effectively and safely manage severely encrusted stents.
Assessing needs of patients and families during the perioperative period at King Abdullah Medical City
Authors: Alsabban Wid , Alhadithi Ahmed , Alhumaidi Faisal Salem , Al Khudhair Abdullah Mutlaq , Altheeb Saeed , Badri Ahmed Saad 
Published: April 2020

Abstract
Background
This paper explores elective surgery patients’ and family members’ needs during the perioperative period, in a specialized hospital in Saudi Arabia. Needs are influenced by context and could differ from a setting to another.

Methods
Two questionnaires, one for the patient group and the other for the family member group, were adopted from a previous similar study. The participants were asked to rate the importance of each need and how much it was satisfied. Data were collected in 5 weeks. Descriptive statistics were used to determine the average rate and standard deviation of each item.

Results
Patients highly rated the need for adequate symptom management in the recovery area. Family members highly rated the importance of being informed if the surgical procedure is taking more time than expected and communicating with the surgeon after the procedure.

Conclusion
Systematically involving the family member in the perioperative care of the patient is advantageous. However, interventions and extent of involvement of the family member to the care of the patient would have to be adapted according to the cultural context.
Managing diabetes in primary care during Ramadan
Authors: Morris David 
Published: April 2020

Individuals with diabetes may wish to fast during the holy month of Ramadan. David Morris provides an overview of the key considerations for practice nurses helping people with diabetes to manage their condition Ramadan is the holiest month of the Islamic calendar, during which healthy adult Muslims fast. Vulnerable people with diabetes can be exempted from fasting during Ramadan; however, many Muslims with diabetes feel strongly committed to observing Ramadan. The adoption of fasting together with alteration of mealtimes, sleeping arrangements and exercise, places physiological demands on the individual that are likely to be greater in those with diabetes. Health professionals involved in the care of these patients need to offer timely advice on the risks associated with fasting in those with diabetes and, where fasting is planned, support and empower these individuals.
Implanty ślimakowe – etyka a wybór
Authors: Tomaszewski Piotr 
Published: April 2020

Tomaszewski Piotr, Implanty ślimakowe – etyka a wybór [Cochlear implants – ethics and choices]. „Kultura – Społeczeństwo – Edukacja” nr 2(14) 2018, Poznań 2018, pp. 155–181, Adam Mickiewicz University Press. ISSN 2300-0422. DOI 10.14746/kse.2018.14.13.
This study discusses the ethical issue of the development of hearing technology in the form of cochlear implants that are used by an ever-growing number of deaf and hard of hearing people. The development of this kind of technology has progressed so quickly all over the world, including Poland, that the deafness paradigms have drastically changed. This may affect, to a greater or lesser degree, not only the implementation of early support programmes, but also the image of the Deaf communities using their respective sign languages on a daily basis. It is therefore necessary to create an eclectic model of education for deaf and hard of hearing people which would allow for the ethical option to integrate the conflicting approaches on the proper procedure for deciding on the language (spoken or signed) and the culture (the hearing or the Deaf one) for the development of deaf and hard of hearing students with cochlear implants or hearing aids.
Experiments and optimization for the WEDM process: A trade-off analysis between surface quality and production rate
Authors: Nguyen Trung Thanh , Dang Xuan Phuong , Nguyen Truong An , Trinh Quang Hung 
Published: April 2020

This work addressed a parameter optimization to simultaneously decrease the root mean square roughness (Rq) as well as the thickness of the white layer (TW) and improve the material removal rate (MRR) for the wire electro-discharge machining (WEDM) of a stainless steel 304 (SS304). The factors considered are the discharge current (C), the gap voltage (VO), the pulse on time (POT), and the wire drum speed (SP). The interpolative radius basic function (RBF) is applied to show the correlation between the varied factors and WEDM performances measured. The optimal selection is chosen using the multi-objective particle swarm optimization (MOPSO). Moreover, a traditional one using the response surface method (RSM) and desirability approach (DA) is adopted to compare the working efficiency of two optimization techniques. The results showed that the optimal findings of the C, POT, VO, and SP are 5.0 A, 1.0 µs, 61.0 V, and 8.0 m/min, respectively. The values of the Rq and TW are decreased by approximately 33.33% and 23.53%, respectively, while the MRR enhances 47.42% at the optimal selection, as compared to the common values used. The BRF-MOPSO can provide better performance than the RSM-DA.
Evidence for Natural Selection and Ethnic Diversity at the Adenylate cyclase 3 Gene Associated with Obesity and Type 2 Diabetes
Authors: YOSHIUCHI ISSEI 
Published: April 2020

Abstract
Background: Diabetes and obesity cause serious complications worldwide, including stroke and cardiovascular disease, and are a global health burden. Diabetes is strongly related with obesity and both are significantly heritable. The prevalence of diabetes and obesity are higher in African populations than in European and Asian populations. In human evolution, natural selection is a key process of genetic survival over generations. Thus, the selection for diabetes- and obesity-related genes is a key mechanism for survival during times of feast and famine. Loss-of-function variations in the adenylate cyclase 3 ( ADCY3 ) gene are associated with obesity and diabetes, while mutations in ADCY3 are also associated with childhood obesity. ADCY3 -deficient mice showed severe obesity, impaired insulin sensitivity, and reduced physical activity. Here, we researched evidence for natural selection at ADCY3 . Methods: We used a three-step genetic method to identify natural selection at ADCY3 using data on four populations from the 1000 Genomes Project and HapMap: Utah residents with Northern and Western European ancestry (CEU), the Yoruba in Ibadan, Nigeria (YRI), Han Chinese in Beijing (CHB) and Japanese in Tokyo (JPT). First we used Wright’s F-statistics (Fst) as a measure of population differentiation to find ethnic diversity at ADCY3 . We then used a long-range haplotype (LRH) test to find significant long haplotypes, and then the integrated haplotype score (iHS) to find natural selection at ADCY3 . Results: We observed high Fst values and significant ethnic diversity at four ADCY3 body mass index (BMI)-associated variations (rs7586879, rs6545814, rs11676272 and rs10182181) between the non-African and African populations. Both LRH and iHS also provided evidence for natural selection at ADCY3 . Conclusions: These observations show evidence for natural selection and ethnic diversity at ADCY3 . Further exploration into the evolution of obesity- and Type 2 diabetes-associated genes is needed.
Protective role of microRNA-9-5p in oxygen glucose deprivation/reperfusion-induced injury in liver sinusoidal endothelial cell
Authors: Duan Yi , Gao Zhifeng , Wang Xiaoyu , Meng Yuanyuan , Zhang Huan 
Published: April 2020

Abstract
Background: Maintenance of the function and survival of liver sinusoidal endothelial cells (LSECs) play a crucial role in hepatic ischemia/reperfusion (I/R) injury, a major cause of liver impairment during surgical treatment. Emerging evidence indicate a critical role of microRNAs in I/R injury. This study aims to investigate whether miR-9-5p exert a protective effect on LSECs in vitro .Methods: We transfected LSECs with miR-9-5p mimic or mimic NC. LSECs were treated with oxygen and glucose deprivation (OGD, 5% CO2 and 95% N2), followed by glucose-free DMEM medium for 6 h, and high-glucose (HG, 30 mmol/L glucose) DMEM medium for 12 h. The biological role of miR-9-5p in I/R-induced LSEC injury was determined. Results: In the in vitro model of OGD/HG injury in LSECs, the expression levels of miR-9-5p were significantly downregulated and those of CXC chemokine receptor-4 (CXCR4) upregulated. LSEC I/R injury led to deteriorated cell death, enhanced oxidative stress and excessive inflammatory response. Mechanistically, we showed that miR-9-5p overexpression significantly upregulated both mRNA and protein levels of CXCR4, followed by rescue of LSECs, ameliorated inflammatory response, and deactivation of pro-apoptotic signaling pathways.Conclusion: miR-9-5p promotes LSEC survival and inhibits apoptosis and inflammatory response in LSECs following OGD/HG injury via downregulation of CXCR4.
Dynamic changes in home-ranges of the subterranean rodent: a case study on Myospalax baileyi
Authors: Zhou Jianwei , Chu Bin , Ji Chengpeng , Zhang Feiyu , Hua Limin 
Published: April 2020

Abstract
BackgroundSubterranean rodents, as ecosystem engineers, excavate and inhabit burrow systems. Their underground space-use mobility is poorly recorded. There is conflicting evidence regarding that burrow system of subterranean rodents, once established, are relatively stable because of high-energy costs of digging. For monitoring data at different stages of a year’s life cycle. We predict that mating and habitat characteristics might influence home-range size and locomotion.MethodsThe present study implemented successive radio-tracking in order to quantify the locomotion and overlap of the plateau zokor (Myospalax baileyi) home-range throughout the year. Home-ranges were calculated according to the 100% minimum convex polygon (MCP) methods. We also examined the relationships of home-range sizes with body mass, vegetation biomass, and soil compaction, respectively.ResultsWe found that sizes of home-ranges varied monthly for both male and female, except for the long winter (from November to March of the following year) challenging to excavate with activity ranges of all individuals concentrated on their own nests. During the mating season, the average size of males’ home-ranges is 3.4 times larger than females’ home-ranges. Males likely expanded the burrows to overlap with multiple females and to enhance their chances of mating. However, there was no overlap between estrus females or males, perhaps by reducing encounters and unnecessary fights. Home-ranges between males and females showed similar in size after courtship ends one month, and interestingly, single zokor’s home-range overlapped with the home-ranges of several neighbors. Most individuals remained territorial and excluded intraspecific from their home-ranges. Besides, the position of the females was stable throughout the year, while half of the males shifted nests and established completely new home-ranges in the non-breeding season, mainly in October. ConclusionsWe conclude that space use of M. baileyi is flexible in response to meet physical contact and food resource. Regarding locomotion of home-range, subterranean plateau zokors to affirm that their home-ranges are dynamics and males shift in space with one breeding cycle.
Investigation of Cadmium Content in Rice in Heilongjiang Province and Health Risk Assessment
Authors: Cao Dongmei , Zhang Chang , Zhang Dongjie 
Published: April 2020

Abstract
We investigated the cadmium content in soils and rice in Cha Hayang, Wuchang, Fangzheng, Xiangshui, and Jiansanjiang areas of Heilongjiang Province, and characterized the effect of rice intake on human health. The samples were analyzed by ICP-MS, and the cadmium transfer in soil-rice system was modeled by the Nemero comprehensive pollution index method. The health risk assessment model was used to study the status of cadmium pollution in rice and its health risk assessment for adults and children. The results showed that the average contents of cadmium in rice were 0.003 (Cha Hayang), 0.016 (Wuchang), 0.006 (Fangzheng), 0.006 (Xiangshui), and 0.005 (Jiansanjiang) mg kg-1. The prediction model developed in this study, including the total heavy metals and pH value of the soil, effectively described the transfer of cadmium in the soil-rice system of Wuchang, Chahayang and Xiangshui paddy fields (with R2 between 0.256 and 0.468). The pollution index of the study area was less than 1. The comprehensive pollution index was 0.037<1, sugesting no pollution, and the comprehensive pollution index was between 0.059 and 0.158. The health risk index of carcinogenic heavy metal cadmium to adults and children in Cyang and JianSanjiang areas was lower than that recommended by USEPA (1 × 10-4), suggesting no risk of cancer. However, the mean values in Wuchang, Fang Zheng and Xiangshui were higher than the maximum acceptable risk recommended by USEPA, suggesting a risk of cancer.
The Effect of Planting Distance and Depth of Water Puddle to Damage Intensity by Rice Yellow Stem Borer (Scirpophaga incertulas Walker) (Lepidoptera: Crambidae) in Relation to Microclimate Change
Authors: Nuzulullia Ulfah , Martono Edhi , Trisyono Y. Andi 
Published: April 2020

The rice yellow stemborer (Scirpophaga incertulas) is one of main pests on rice which may attack at all growth stages. The weather was considered one of influencing factors against its infestation. Therefore, this research was conducted to recognize microclimate factors affecting the infestation of S. incertulas. The experiment was carried out in Institute for Pest Forecasting, Jatisari Karawang from January-April 2017. The investigation was arranged in Factorial of Blocked Randomized Design with four repetitions and combinations of treatment factors, i.e. planting distance (conventional and jajar legowo 2 : 1) and depth of puddle (5 cm, 0 cm, and intermittent). The observation was performed from one to 12 weeks after planting. At the same time, three weather factors (temperature, relative humidity and rainfall) were observed in four West Java regencies i.e. in Bekasi, Karawang, Subang and Indramayu. The results showed that the conventional and the jajar legowo schemes are influenced by the micro air temperature. Both planting distance and depth of water puddle treatment were influenced by the micro air temperature. Microclimate factors which influenced the intensity of infestation were air temperature, humidity, water temperature, and light intensity. The weather factor showing effects in Bekasi, Karawang, and Indramayu was rainfall. However, the three weather factors did not affect on the acreage of pest infestation in Subang.