bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful treatment of pyopneumothorax secondary to Streptococcus constellatus infection with linezolid: a case report and review of the literature
Authors: Zhang Zhaorui , Xiao Binbin , Liang Zhixin 
Published: October 2020

Abstract
Background
Pyopneumothorax secondary to Streptococcus constellatus infection is a clinically rare event, and few cases have been reported.

Case presentation
We report the case of a 55-year-old Han Chinese man with underlying diabetes who presented with fever of 17 days duration. A pulmonary computed tomography scan revealed right-sided massive pyopneumothorax. A culture of the pleural effusion and blood grew S. constellatus. A drug sensitivity test showed that the isolate was sensitive to linezolid, penicillin G, cefotaxime, vancomycin, and cefuroxime. Our patient was treated with linezolid for a total of 6 weeks. Subsequently, his chest computed tomography scan showed improved lung condition.

Conclusion
To the best of our knowledge, this is the first case of pyopneumothorax secondary to S. constellatus to be treated with linezolid. Pyopneumothorax may be caused by streptococcal infection, and linezolid is another good choice for treatment.
Dynamic service migration in ultra-dense multi-access edge computing network for high-mobility scenarios
Authors: Lin Haowei , Xu Xiaolong , Zhao Juan , Wang Xinheng 
Published: October 2020

AbstractThe multi-access edge computing (MEC) has higher computing power and lower latency than user equipment and remote cloud computing, enabling the continuing emergence of new types of services and mobile application. However, the movement of users could induce service migration or interruption in the MEC network. Especially for highly mobile users, they accelerate the frequency of services’ migration and handover, impacting on the stability of the total MEC network. In this paper, we propose a hierarchical multi-access edge computing architecture, setting up the infrastructure for dynamic service migration in the ultra-dense MEC networks. Moreover, we propose a new mechanism for users with high mobility in the ultra-dense MEC network, efficiently arranging service migrations for users with high-mobility and ordinary users together. Then, we propose an algorithm for evaluating migrated services to contribute to choose the suitable MEC servers for migrated services. The results show that the proposed mechanism can efficiently arrange service migrations and more quickly restore the services even in the blockage. On the other hand, the proposed algorithm is able to make a supplement to the existing algorithms for selecting MEC servers because it can better reflect the capability of migrated services.
Geometric modeling and applications of generalized blended trigonometric Bézier curves with shape parameters
Authors: Maqsood Sidra , Abbas Muhammad , Miura Kenjiro T. , Majeed Abdul , Iqbal Azhar 
Published: October 2020

AbstractA Bézier model with shape parameters is one of the momentous research topics in geometric modeling and computer-aided geometric design. In this study, a new recursive formula in explicit expression is constructed that produces the generalized blended trigonometric Bernstein (or GBT-Bernstein, for short) polynomial functions of degreem. Using these basis functions, generalized blended trigonometric Bézier (or GBT-Bézier, for short) curves with two shape parameters are also constructed, and their geometric features and applications to curve modeling are discussed. The newly created curves share all geometric properties of Bézier curves except the shape modification property, which is superior to the classical Bézier. The$C^{3}$C3and$G^{2}$G2continuity conditions of two pieces of GBT-Bézier curves are also part of this study. Moreover, in contrast with Bézier curves, our generalization gives more shape adjustability in curve designing. Several examples are presented to show that the proposed method has high applied values in geometric modeling.
Oblique explicit wave solutions of the fractional biological population (BP) and equal width (EW) models
Authors: Abdel-Aty Abdel-Haleem , Khater Mostafa M. A. , Baleanu Dumitru , Abo-Dahab S. M. , Bouslimi Jamel , Omri M. 
Published: October 2020

AbstractThis research uses the extended exp-$( -\varphi(\vartheta ) ) $(−φ(ϑ))-expansion and the Jacobi elliptical function methods to obtain a fashionable explicit format for solutions to the fragmented biological population and the same width models that depict popular logistics because of deaths or births. In mathematical terminology, the linear, hyperbolic, and trigonometric equation solutions that have been found describe several innovative aspects from the two models. Sketching these solutions in different types is used to give them more details. The accuracy and performance of the method adopted show their ability to be applied to various nonlinear developmental equations.
Existence and uniqueness results for Φ-Caputo implicit fractional pantograph differential equation with generalized anti-periodic boundary condition
Authors: Ahmed Idris , Kumam Poom , Abdeljawad Thabet , Jarad Fahd , Borisut Piyachat , Demba Musa Ahmed , Kumam Wiyada 
Published: October 2020

AbstractThe present paper describes the implicit fractional pantograph differential equation in the context of generalized fractional derivative and anti-periodic conditions. We formulated the Green’s function of the proposed problems. With the aid of a Green’s function, we obtain an analogous integral equation of the proposed problems and demonstrate the existence and uniqueness of solutions using the techniques of the Schaefer and Banach fixed point theorems. Besides, some special cases that show the proposed problems extend the current ones in the literature are presented. Finally, two examples were given as an application to illustrate the results obtained.
On multivalued L-contractions and an application
Authors: Barakat M. A. , Aydi Hassen , Mukheimer Aiman , Soliman Ahmed A. , Hyder Abdallah 
Published: October 2020

AbstractThe aim of this paper is to present several fixed-point results for L-contractive multivalued mappings involving θ-functions in the class of metric spaces. We also give some examples in support of the related concepts and presented results. A homotopy result is also provided.
Offering mental health first aid to a person after a potentially traumatic event: a Delphi study to redevelop the 2008 guidelines
Authors: Chalmers Kathryn J. , Jorm Anthony F. , Kelly Claire M. , Reavley Nicola J. , Bond Kathy S. , Cottrill Fairlie A. , Wright Judith 
Published: October 2020

Abstract
Background
Trauma has a major impact on the mental health and wellbeing of people globally. Friends, family and members of the public are often well positioned to provide initial assistance if someone is experiencing extreme distress following a potentially traumatic event. Expert consensus guidelines for high income, Western countries on how to do this were published in 2008. The aim of the current study was to re-develop these guidelines to ensure they are current and reflect best practice.

Methods
The Delphi consensus method was used to determine which helping statements should be included in the guidelines. Helping statements were derived from a systematic search of literature that considered how a member of the public could help someone experiencing extreme distress following a potentially traumatic event. Two expert panels, comprising 28 mental health professionals with expertise in managing trauma and 26 consumer advocates, rated each statement. Statements were accepted for inclusion in the guidelines if they were endorsed by at least 80% of each panel.

Results
Out of 183 statements, 103 were endorsed as appropriate helping actions in providing assistance to someone experiencing extreme distress following a potentially traumatic event. These statements were used to form the re-developed guidelines.

Conclusion
This study has resulted in a more comprehensive set of guidelines than the original version, with the endorsement of 103 helping actions, compared to 65 previously. The updated guidelines better represent the complexities of experiencing trauma and the considered approach required when providing first aid after a potentially traumatic event. The additional guidance on providing initial assistance, talking about the trauma, offering short-term assistance and seeking appropriate professional help reflects current knowledge. A notable addition is the inclusion of content on how a first aider can assist after a disclosure of abuse. The guidelines are available to the public and will inform future updates of Mental Health First Aid training courses.
5-Hydroxytryptamine-3 receptor antagonist and dexamethasone as prophylaxis for chemotherapy-induced nausea and vomiting during moderately emetic chemotherapy for solid tumors: a multicenter, prospective, observational study
Authors: Matsui Reiko , Suzuki Kenichi , Takiguchi Tomomi , Nishio Makoto , Koike Takeshi , Hayashi Toshinobu , Seto Takashi , Kogure Yuki , Nogami Naoyuki , Fujiwara Kimiko , Kaneda Hiroyasu , Harada Tomohiko , Shimizu Satoru , Kimura Masashi , Kenmotsu Hirotsugu , Shimokawa Mototsugu , Goto Koichi 
Published: October 2020

Abstract
Background
Of patients receiving moderate emetic risk chemotherapy (MEC), 30–90% experience chemotherapy-induced nausea and vomiting (CINV); however, the optimal antiemetic treatment remains controversial.

Methods
In this multicenter, prospective, observational study of adults treated with MEC while receiving chemotherapy for various cancer types in Japan, the enrolled patients kept diaries documenting CINV. All participants received a 5-hydroxytryptamine-3 receptor antagonist and dexamethasone.

Results
Of the 400 patients enrolled from May 2013 to January 2015, 386 were eligible for evaluation. The median age was 64 (range, 26–84). The overall complete response (CR; no emetic events and no antiemetic measures) rate was 64%. The proportion of patients showing CR was low in the carboplatin (CBDCA)- and oxaliplatin-based chemotherapy groups, especially among women. We showed that the CR rates in men were high in the CBDCA (AUC5) + etoposide (ETP) (80%), capecitabine plus oxaliplatin (CAPOX) (78%), and CBDCA+ paclitaxel (PTX) groups for lung cancer (73%). Total control (TC; no emetic events, no antiemetic measures, and no nausea) and complete control (CC; no emetic events, no antiemetic measures, and less than mild nausea) were achieved in 51 and 61% of patients, respectively. Logistic regression analysis revealed history of motion sickness, history of pregnancy-associated vomiting and CBDCA-based chemotherapy as risk factors for CR and history of motion sickness and history of pregnancy-associated vomiting as risk factors for TC. Additional, Ages ≥65 years is an independent predictive factor for achieving TC.

Conclusions
Our data showed that two antiemetics were insufficient to control CINV in patients receiving CBDCA- or oxaliplatin-based chemotherapy. However, two antiemetics may be sufficiently effective for elderly male patients receiving CBDCA (AUC5) + ETP, CBDCA+PTX for lung cancer, or CAPOX. Additionally, we consider that three antiemetics are necessary for women with colorectal cancer receiving CAPOX. Risk factor analysis related to CR showed that CINV prophylaxis in patients treated with CBDCA-based chemotherapy was generally supportive of the guideline-recommended three antiemetics. However, the control of nausea in patients receiving non-CBDCA-based chemotherapy is a key point to note. The further individualization of antiemetic regimens for patients receiving MEC based on both types of chemotherapy regimens and sex is needed.
An augmented reality learning system for Japanese compound verbs: study of learning performance and cognitive load
Authors: Geng Xuewang , Yamada Masanori 
Published: October 2020

AbstractTo address the difficulties related to acquiring Japanese compound verbs, which lack the clarity of verb combinations and the opacity of compound verb meanings, we designed and developed an augmented reality (AR) learning system based on image schema and AR animations. We investigated the effects of the AR-based language learning system developed in this study on the learning performance and cognitive load of an AR learning system and paper-based image schema materials. This study also examined the correlation between learning performance and cognitive load. Learners of these two learning methods had significantly improved performance on post-tests. Especially, regarding the retention of knowledge, the AR learning system was more effective. However, there was no significant difference in the perceived cognitive loads between the two learning methods. It is also found that the learning performance of the two learning methods was related to the perceived different types of cognitive load.
Sporting participation following the operative management of chondral defects of the knee at mid-term follow up: a systematic review and meta-analysis
Authors: Robinson P. G. , Williamson T. , Murray I. R. , Al-Hourani K. , White T. O. 
Published: October 2020

Abstract
Purpose
The purpose of this study was to perform a systematic review of the reparticipation in sport at mid-term follow up in athletes who underwent biologic treatment of chondral defects in the knee and compare the rates amongst different biologic procedures.

Methods
A search of PubMed/Medline and Embase was performed in May 2020 in keeping with Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. The criteria for inclusion were observational, published research articles studying the outcomes and rates of participation in sport following biologic treatments of the knee with a minimum mean/median follow up of 5 years. Interventions included microfracture, osteochondral autograft transfer (OAT), autologous chondrocyte implantation (ACI), matrix-induced autologous chondrocyte implantation (MACI), osteochondral allograft, or platelet rich plasma (PRP) and peripheral blood stem cells (PBSC). A random effects model of head-to-head evidence was used to determine rates of sporting participation following each intervention.

Results
There were twenty-nine studies which met the inclusion criteria with a total of 1276 patients (67% male, 33% female). The mean age was 32.8 years (13–69, SD 5.7) and the mean follow up was 89 months (SD 42.4). The number of studies reporting OAT was 8 (27.6%), ACI was 6 (20.7%), MACI was 7 (24.1%), microfracture was 5 (17.2%), osteochondral allograft was 4 (13.8%), and one study (3.4%) reported on PRP and PBSC. The overall return to any level of sport was 80%, with 58.6% returning to preinjury levels. PRP and PBSC (100%) and OAT (84.4%) had the highest rates of sporting participation, followed by allograft (83.9%) and ACI (80.7%). The lowest rates of participation were seen following MACI (74%) and microfracture (64.2%).

Conclusions
High rates of re-participation in sport are sustained for at least 5 years following biologic intervention for chondral injuries in the knee. Where possible, OAT should be considered as the treatment of choice when prolonged participation in sport is a priority for patients. However, MACI may achieve the highest probability of returning to the same pre-injury sporting level.

Level of evidence
IV
Cortical thickness of the tibial diaphysis reveals age- and sex-related characteristics between non-obese healthy young and elderly subjects depending on the tibial regions
Authors: Maeda Keisuke , Mochizuki Tomoharu , Kobayashi Koichi , Tanifuji Osamu , Someya Keiichiro , Hokari Sho , Katsumi Ryota , Morise Yusuke , Koga Hiroshi , Sakamoto Makoto , Koga Yoshio , Kawashima Hiroyuki 
Published: October 2020

Abstract
Purpose
This study aimed to evaluate the age- and sex-related characteristics in cortical thickness of the tibial diaphysis between non-obese healthy young and elderly subjects as reference data.

Methods
The study investigated 31 young subjects (12 men and 19 women; mean age, 25 ± 8 years) and 54 elderly subjects (29 men and 25 women; mean age, 70 ± 6 years). Three-dimensional estimated cortical thickness of the tibial diaphysis was automatically calculated for 5000–9000 measurement points using the high-resolution cortical thickness measurement from clinical computed tomography data. In 12 assessment regions created by combining three heights (proximal, central, and distal diaphysis) and four areas of the axial plane at 90° (medial, anterior, lateral, and posterior areas) in the tibial coordinate system, the standardized thickness was assessed using the tibial length.

Results
As structural characteristics, there were no differences in the medial and lateral thicknesses, while the anterior thickness was greater than the posterior thickness in all groups. The sex-related difference was not shown. As an age-related difference, elderly subjects showed greater or lesser cortical thickness than the young subjects, depending on the regions of the tibia.

Conclusions
Cortical thickness was different depending on sex, age, and regions in the tibia. The results of this study are of clinical relevance as reference points to clarify the causes of various pathological conditions for diseases.

Level of evidence
Level 3.
Advances on inorganic scintillator-based optic fiber dosimeters
Authors: Ding Liang , Wu Qiong , Wang Qun , Li Yamei , Perks Richard M. , Zhao Liang 
Published: October 2020

AbstractThis article presents a new perspective on the development of inorganic scintillator-based fiber dosimeters (IOSFDs) for medical radiotherapy dosimetry (RTD) focusing on real-time in vivo dosimetry. The scintillator-based optical fiber dosimeters (SFD) are compact, free of electromagnetic interference, radiation-resistant, and robust. They have shown great potential for real-time in vivo RTD. Compared with organic scintillators (OSs), inorganic scintillators (IOSs) have larger X-ray absorption and higher light output. Variable IOSs with maximum emission peaks in the red part of the spectrum offer convenient stem effect removal. This article outlines the main advantages and disadvantages of utilizing IOSs for SFD fabrication. IOSFDs with different configurations are presented, and their use for dosimetry in X-ray RT, brachytherapy (BT), proton therapy (PT), and boron neutron capture therapy (BNCT) is reviewed. Challenges including the percentage depth dose (PDD) deviation from the standard ion chamber (IC) measurement, the angular dependence, and the Cherenkov effect are discussed in detail; methods to overcome these problems are also presented.
A long-term survivor of clear cell sarcoma-like tumor of the gastrointestinal tract with liver metastasis: a case report
Authors: Okada Takuhisa , Hirano Yasumitsu , Ishikawa Shintaro , Kondo Hiroka , Ishii Toshimasa , Yamaguchi Shigeki 
Published: October 2020

Abstract
Background
Clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLTGT) is extremely rare. It is a mesenchymal neoplasm that usually forms in the small intestine of adolescents and young adults, is prone to local recurrence and metastasis, and has a high mortality rate. We report a patient with CCSLTGT with lymph node- and liver metastases, who continues to survive 6 years after initial surgical resection.

Case presentation
A 38-year-old woman presented with lightheadedness. Laboratory analysis revealed anemia (hemoglobin, 6.7 g/dL), and enhanced computed tomography (CT) demonstrated a mass in the small intestine, about 6 cm in diameter, with swelling of 2 regional lymph nodes. Double-balloon small intestine endoscopic examination revealed a tumor accompanied by an ulcer; the biopsy findings suggested a primary cancer of the small intestine. She was admitted, and we then performed a laparotomy for partial resection of the small intestine with lymph node dissection. Pathologic examination revealed CCSLTGT with regional lymph node metastases. About 3 years later, follow-up CT revealed a single liver metastasis. Consequently, she underwent a laparoscopic partial liver resection. Histopathologic examination confirmed that the liver metastasis was consistent with CCSLTGT. It has now been 3 years without a recurrence.

Conclusion
Repeated radical surgical resection with close follow-up may be the only way to achieve long-term survival in patients with CCLSTGT.
Delayed postoperative bleeding following lobectomy caused by the sharp tip of a suture: a case report
Authors: Kawamura Tomoyuki , Suzuki Hisashi , Kiyoshima Moriyuki 
Published: October 2020

Abstract
Background
Postoperative bleeding is a rare but serious complication occasionally caused by hard surgical materials, such as staples. Postoperative hemorrhage caused by sutures is very rare.

Case presentation
A 75-year-old man with lung cancer underwent right lower lobectomy. Eleven days after surgery, he developed a haemothorax. Emergency thoracotomy revealed arterial bleeding from a pinhole injury in the parietal pleura caused by a monofilament non-absorbable suture tip used during the initial surgery.

Conclusions
Postoperative bleeding is a serious complication, and as sutures are often used in surgery, it is important to be cautious while using this material.
Kidney failure after lung transplantation in systemic scleroderma: a case report with literature review
Authors: Ishide Takashi , Nishi Hiroshi , Ambe Hiroko , Honda Kenjiro , Nakamura Motonobu , Sato Jiro , Yamamoto Kota , Sato Masaaki , Nangaku Masaomi 
Published: October 2020

Abstract
Background
Systemic scleroderma (SSc) involves multiple organs including the skin, the lung, the kidney, and the esophagus. Nowadays, patient life prognosis has substantially improved due to more appropriate management of lung complications, including lung transplantation. However, the extension of their survival may increase SSc patients with chronic kidney diseases and requiring renal replacement therapy (RRT).

Case presentation
A 51-year-old female with SSc who underwent unilateral deceased-donor lung transplantation was referred because of progressive renal dysfunction. Despite no episodes of scleroderma renal crisis, her renal function gradually deteriorated for 2 years with her serum creatinine level increasing from 0.5 mg/dL at transplantation to 4.3 mg/dL. Although we reinforced antihypertensive treatment and reduced calcineurin inhibitor dose, she thereafter developed symptomatic uremia. Due to impaired manual dexterity with contracture of the interphalangeal joints, no caregivers at home, and kidney transplantation donor unavailability, maintenance hemodialysis was chosen as RRT modality. Further, due to the narrowing of superficial vessels in the sclerotic forearm skin and post-transplant immunocompromised status, the native left brachiocephalic arteriovenous fistula was created. Post-operative course was uneventful while any sign of cutaneous infection and pulmonary hypertension was closely monitored. Our literature review also indicates several difficulties with initiating and maintaining RRT in patients with SSc although case reports of kidney failure after lung transplanation in SSc were not accumulated.

Conclusions
With respect to initiating RRT for post-lung transplant patients with SSc, the clinical course of our case exemplifies recent complex trends of renal management. The optimal modality with secured initiation of RRT should be carefully determined based on the severity and risk for the cardiopulmonary, peripheral vascular, cutaneous, and systemic or local infectious complications.