bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pemodelan Pengaruh Imunisasi DPT Terhadap Angka Kematian Bayi di Jawa Timur Tahun 2016 Menggunakan Pendekatan Regresi Nonparametrik Spline
Authors: Al Azies Harun , Trishnanti Dea 
Published: February 2020

East Java is one of the provinces with a high IMR level. Based on the District / City report in East Java, in 2006 it was 0.035 live births and became 0.0032 live births in 2008. Identification of factors that influence both indicators correctly can be done by modeling, namely by nonparametric regression analysis. The nonparametric regression approach used is Spline, with its strengths the model tends to look for estimates wherever the data moves. This is because there is a knot point which is a joint fusion point which indicates a change in data behavior patterns. Based on the results of analysis and discussion using Spline analysis, it is known that the factors that influence the incidence of IMR in East Java are toddlers receiving type 3 DPT immunization. The best Spline nonparametric regression model is a linear Spline model with three point knots. The GCV value produced was 51.34. Factors of children under five obtained immunizations affecting infant mortality rates in districts / cities in East Java in 2016. This research still uses linear spline regression program with a combination of one, two, and three knots with R square of 65.92%. The need to develop programs into quadratic and cubic orders using a combination of knots.
Jawa Timur merupakan salah satu provinsi dengan tingkat AKB yang tinggi. Berdasarkan laporan Kabupaten/Kota di Jawa Timur, pada tahun 2006 sebesar 0,035 kelahiran hidup dan menjadi 0,0032 kelahiran hidup pada tahun 2008. Jika suatu daerah dengan AKB yang tinggi, maka terdapat kemungkinan bahwa daerah sekitarnya akan memiliki beban AKB yang sama pula. Identifikasi faktor-faktor yang mempengaruhi kedua indikator secara tepat dapat dilakukan dengan pemodelan, yaitu dengan analisis regresi nonparametrik. Pendekatan regresi nonparametric yang digunakan adalah Spline, dengan kelebihannya model cenderung mencari estimasinya kemanapun data tersebut bergerak. Hal ini dikarenakan terdapat titik knot yang merupakan titik perpaduan bersama yang menunjukkan terjadinya perubahan pola perilaku data. Berdasarkan hasil analisis dan pembahasan dengan menggunakan analisis Spline diketahui bahwa faktor yang berpengaruh terhadap kejadian AKB di Jawa Timur adalah balita memperoleh imunisasi DPT tipe 3. Model regresi nonparametrik Spline terbaik adalah model Spline linear dengan tiga titik knot. Nilai GCV yang dihasilkan adalah 51,34. Faktor balita memperoleh imunisasi mempengaruhi angka kematian bayi di kabupaten/kota di Jawa Timur pada tahun 2016. Penelitian ini masih menggunakan program regresi spline linier dengan kombinasi satu, dua, dan tiga knot dengan R square sebesar 65,92%. Perlu adanya pengembangan program menjadi orde kuadratik dan kubik dengan menggunakan kombinasi knot.
APLICABLE HORIZONTAL WIND TURBIN MODEL FAMILY SCALE
Authors: Rahayu Nitabian Iftita 
Published: February 2020

The aplicabel of horizontal wind turbine. There is two alternative two develop wind turbine design that generator or blade, in order to develop horizontal wind turbine This reesearch select the partdesign to develop generator. The angle design betwen coil and magnetic field must to optimal degree. There are seven angle from 60 degree to 120 degee which angle test. There is range of the optimal degree from 80 degree to 100 degree to develop wihd turbine.
TASMIMOPANAS : Modified Paper Using Waste of Pineapple as Purifier of Waste Cooking Oil
Authors: Alfarisi Salman 
Published: February 2020

Cooking oil was necessary of household to used when processed food ingridients. Waste cooking oil was contained free radicals can potentially oxidize organs. This problem overcome with rice straw and waste of pineapple which waste cooking oil was recycled by them. The utilization cellulose component on rice straw and waste of pineapple as natural active carbon can helped this problem. The absoption of subtances in waste cooking oil used paper from rice straw which heat together with Na2SO3 solvent while grinding processed with waste of pineapple to made pulp.
DESIGN OF VERTICAL AXIS SAVONIUS WINDMILL FOR GENERATING ELECTRICITY USING PERMANENT MAGNET
Authors: Rochman Sagita 
Published: February 2020

At present the use of wind energy in Indonesia is still relatively low, but has enormous potential. One reason is because the average wind speed in the territory of Indonesia is classified as low wind speed, which ranges from 3 m / s to 5 m / s making it difficult to produce electrical energy on a large scale. However, the wind potential in Indonesia is available almost all year long, making it possible to develop small-scale power generation systems. Innovations in modifying windmills need to be developed so that in conditions of low wind speeds can produce electrical energy.
In this research, a prototype was developed by designing a vertical axis windmill power plant model Savonius using a permanent magnet generator, which can produce optimal electrical energy by utilizing relatively low wind speeds.From the generator test it was found that with a rotor rotation of 50 rpm up to 500 rpm can produce an electrical voltage of 0.02V to 10V and an electric current of 0.60A to 4.53A.
PENGARUH MODEL PEMBELAJARAN DAN SELF EFFICACY TERHADAP KEMAMPUAN PEMECAHAN MASALAH SISWA PADA MATERI SISTEM EKSKRESI
Authors: Harahap Hasmi Syahputra , Dongoran Herawati 
Published: February 2020

Penelitian ini bertujuan untuk mengetahui pengaruh serta interaksi model pembelajaran dan self efficacy terhadap: (1) Kemampuan pemecahan masalah siswa kelas XI di MAN 1 Medan. Metode penelitian menggunakan kuasi eksperimen dengan sampel penelitian sebanyak 3 kelas dari 6 kelas XI IPA yang diambil dengan menggunakan metode purposive sampling. Instrumen penelitian menggunakan tes kemampuan pemecahan masalah dan keterampilan proses sains siswa dalam bentuk tes uraian, dan nontes berupa angket self efficacy. Teknik analisis menggunakan statistik deksriptif dan Statistic Inferensial Parametric atau Multivariate Analysis of Variance (MANAVA) dengan taraf signifikan 5% dengan SPSS 20. Hasil penelitian menunjukkan: (1) Ada pengaruh yang signifikan model pembelajaran terhadap kemampuan pemecahan masalah (p=0,024<0,05); (2) Ada pengaruh yang signifikan self efficacy terhadap kemampuan pemecahan masalah (p=0,000<0,05); (3) Ada interaksi yang signifikaan antara model pembelajaran dan self efficacy siswa terhadap kemampuan pemecahan masalah (p=0,004<0,05). Sebagai tindak lanjut dari hasil penelitian ini diharapkan kepada guru untuk dapat menerapkan model pembelajaran dan self efficacy pada materi sistem ekskresi dalam upaya meningkatkan kemampuan pemecahan masalah, dan keterampilan proses sains siswa di sekolah
Pembelajaran Berbasis Masalah dalam Meningkatkan Kemampuan Pemecahan Masalah Matematika
Authors: Noviantii Erna , Yuanita Putri , Maimunah Maimunah 
Published: February 2020

This study aims to improve the learning process and the student’s mathematical problem solving skill by applying Problem Based Learning (PBL) model. This type of research is classroom action research with two cycles. This research was conducted in collaboration between researcher and teacher of mathematics. Subjects were students of class SMPN 9 Pekanbaru. Study was conducted in the odd semester of academic year 2019/2020. The research instrument consists of mathematical learning instruments and instruments to collect data. Mathematical learning instruments used in this study are syllabus, lesson plans, and activity sheets. Data collection instruments used in this study is observation sheets and mathematical problem solving tests. Data analysis technique in this study is analysis descriptive narrative of qualitative data and descriptive statistical analysis of quantitative data. The result of this study showed that the implementation of PBL improved the learning process and the student’s mathematical problem solving skill. The student’s average value in cycle I which is 70,27 had improved to 84,07 in cycle II. The improvement also found in the indicator average value in understanding the problem (94,99), planning a solution (69,71), implementing the pland (82,77), and checking again (54,85). This study concludes that the implementation of PBL improved the student’s mathematical problem solving skill at class SMPN 9 Pekanbaru.
Pengaruh Media Pembelajaran Geogebra Pada Materi Fungsi Kuadrat Terhadap Motivasi dan Hasil Belajar Peserta Didik
Authors: Hamidah Nur , Afidah Iis Nur , Setyowati Lutfi Wahyu , Sutini Sutini , Junaedi Junaedi 
Published: February 2020

This study aims to determine the effect of Geogebra learning media on the quadratic function material on motivation and learning outcomes in class IX MTsN Gresik. The method of this research used experimental research mapped in class IX –C and IX-D. Class IX-C as a control class and class IX-D as an experimental class. Where each class there are 28 students. Data collection techniques used were pretest, post-test and questionnaire. Pretest and post-test were used to determine effect of Geogebra on student learning outcomes, while the questionnaire was used to determine the effect of Geogebra on students’ learning motivation. Data analysis uses z-test analysis. The results of the study showed that : (1) Geogebra learning media on quadratic function material influences students’ learning motivation, (2) student learning outcomes using Geogebra learning media on quadratic function material are better than students who do not use Geogebra.
Keyword: Geogebra, motivation and learning outcomes, quadratic function.
Immune Checkpoint Blockade in Gastrointestinal Cancers: The Current Status and Emerging Paradigms
Authors: Miljanic Mihailo , Capasso Anna , Triplett Todd A. , Eckhardt S. Gail , Aung Kyaw L. 
Published: February 2020

AbstractImmunotherapy is a rapidly evolving treatment paradigm that holds promise to provide long-lasting survival benefits for patients with cancer. This promise, however, remains unfulfilled for the majority of patients with gastrointestinal (GI) cancers, as significant limitations in efficacy exist with immune checkpoint inhibitors (ICIs) in this disease group. A plethora of novel combination treatment strategies are currently being investigated in various clinical trials to make them more efficacious as our understanding of molecular mechanisms mediating resistance to immunotherapy advances. In this article, we summarize the current status of immune checkpoint blockade in GI cancers and discuss the biological rationales that underlie the emerging treatment strategies being tested in ongoing clinical trials in combination with ICIs. We also highlight the promising early results from these strategies and provide future perspectives on enhancing response to immunotherapy for patients with GI cancers.
Pneumocystis Infection in Two Patients Treated with Both Immune Checkpoint Inhibitor and Corticoids
Authors: Sadek Maroun , Loizidou Angela , Drowart Annie , Van den Wijngaert Sigi , Gomez-Galdon Maria , Aspeslagh Sandrine 
Published: February 2020

Abstract
The introduction of immune checkpoint inhibitor (ICI) targeting cytotoxic T-lymphocyte-associated antigen-4 and programmed cell death receptor 1 has dramatically improved clinical outcome for cancer patients. Nevertheless, this treatment can be associated with immune-related adverse events (irAEs) which sometimes need management with prolonged immune suppression. In order to analyze the risk of Pneumocystis jiroveci pneumonia (PJP) in this population, all PJP cases at our oncological hospital between 2004 and 2019 were searched. Only two cases were found in patients treated with ICI (480 patients received ICI during that period). The first was treated with both ipilimumab and nivolumab for metastatic melanoma and required long-term corticosteroids plus infliximab for immune-related colitis. The second received both pembrolizumab and brentuximab for Hodgkin's lymphoma and received corticosteroids for macrophage-activating syndrome. These two cases illustrate that PJP is rare but might be severe in the ICI population and should be differentiated from tumor progression or irAE.
Factors Associated With Orthopaedic Resident Burnout: A Pilot Study
Authors: Driesman Adam S. , Strauss Eric J. , Konda Sanjit R. , Egol Kenneth A. 
Published: February 2020

Introduction:
Burnout is an occupational hazard for physicians at all stages of training and medical practice. The purpose of the current study was to determine whether residency factors, with the use of an activity monitor, including the amount of exercise, have any impact on burnout among orthopaedic surgery residents in varying years of training.

Methods:
Orthopaedic residents at a single institution were recruited immediately before beginning a new clinical rotation and followed for four weeks. On enrollment, the participants were given a wrist-worn activity monitor (Fitbit Flex) and instructed on its use for tracking physical activity. REDCap was used to collect burnout levels (as assessed by using the Maslach Burnout Inventory and the Patient Health Questionnaire-9), which were completed a total of five times, once at enrollment and weekly during the study period.

Results:
Twenty-seven residents were enrolled, including 13 junior residents (interns and second years) and 14 senior residents (third, fourth, and fifth years). Seven residents were on fracture rotations, whereas 20 were not. As measured by using the Maslach Burnout Inventory, juniors were more emotionally exhausted (P = 0.01) and depersonalized (P = 0.027). No difference in the objective physical activity data as measured by using the Fitbit Flex and no difference in the self-reported hours of sleep were observed. Residents on orthopaedic trauma rotations also reported significantly higher rates of emotional exhaustion and depersonalization (P < 0.001) than other residents and were more physically active on average (P < 0.030).

Discussion:
Although depersonalization and depression are common symptoms seen among orthopaedic surgery residents, this study demonstrated that quality of life improves markedly as they progress through their residency training. Residents on orthopedic trauma rotations have greater levels of emotional exhaustion and depersonalization. This pilot study suggests that burnout prevention programs should begin at the start of training to provide residents with strategies to combat and then reinforced while on orthopaedic trauma rotations.

Level of Evidence:
Level III Diagnostic Study
El diablo está en los detalles
Authors: González de Canales Francisco 
Published: February 2020

Explica el paso del autor por la Cátedra Blanca y su relación con su posterior trayectoria en los ámbitos de la divulgación, la academia y la profesión.
It wasn’t even my third week in Barcelona when Carlos asked for a facade section at 1:10 scale of the project idea. That was a surprise. Not only in terms of changing the usual order in the development of the project, but because I came from a context in which the enemy was the mannerism already present since the 70s; in such context, starting the project by the detail seemed highly suspicious to me. I could not understand how going back to detail could make sense in a world that we already recognized as changes and flows in constant circulation. What resistance to it could “the detail” detail ? In this my last career course, my training until then based on diagrams and strategies seemed much more coherent to me, and that other thing seemed to me like a kind of self-absorption in the excessively particular, or worse, as a castling of the architects about themselves and their own ‘styling’ in the face of convulsing times. But the insistence was huge. Carlos repeated as a mantra that what interested him most in architecture were ‘the 3 centimeters’, those in which the materials are found, and he expressed this in the talks with which he presented his work, in the construction visits that we made throughout that year ...In these 20 years since that course, this need for coherence across the different scales of the processes has led a good part of my informational, academic and professional career.
Architecture and Entrepreneurship
Authors: Shumkov Ivan 
Published: February 2020

Ivan Shumkov is a New York based entrepreneur, architect, educator and the Founder of Build Academy. Below is a snapshot of a bit of his journey and his work that may be of inspiration to others.
"In this phase of my life, I’m a New York based entrepreneur, architect, educator and the Founder of Build Academy. Below is a snapshot of a bit of my journey and my work that hopefully can be of inspiration to others. Looking back at my journey, I try to connect the dots, see how I got here and where I’m heading. Architecture has the unique capacity to manifest new realities and raise people’s consciousness. It opens so many paths that can make a positive difference in the world if followed thoroughly with passion and perseverance. My life and work maintain a bridge between architecture, entrepreneurship, research, teaching, leadership and social activism. I demonstrate the non-traditional path of an architect and highlight the potential within the realm of architecture. The impact of my work can be seen from the social impact projects that I was involved with, to the thousands of people that he has educated and inspired through my teaching in universities and online. My work as entrepreneur went beyond into starting a global movement for resilient, sustainable, inclusive and conscious communities and cities. I am willing to collaborate with anyone who shares the same passion for discovering the world and making a positive difference into it."
Vivir sin cocina
Authors: Puigjaner Barberà Anna 
Published: February 2020

¿Qué ocurriría si eliminásemos la cocina de nuestras casas? Hay algo provocativo y a la vez revelador en el acto de suprimir la cocina del espacio doméstico. El rechazo social generalizado que a menudo produce esa propuesta, nos puede permitir entender lo profundamente arraigadas que se encuentran algunas de nuestras ideas -y afectos- sobre ese espacio doméstico.
There is something provocative and at the same time revealing in the act of eliminating the kitchen from the house. The generalized social refusal that this action often provokes allows us to understand the deep affection and assumptions that this domestic space arouses. Ideologically speaking, the kitchen has had a main role in the historical definition of the idea of home and the family, and subsequently, in the creation of gender biased relationships within the domestic sphere. In that sense, an image has been forged of the kitchen as a space where women could take responsibility for domestic work alone, thanks to factors such as its proper design and adequate arrangement amidst a care-based system of social value, rather than economic gain.The kitchen is where domestic work has progressively lost its economic value and become instead a labor of love, as Silvia Federici names it. Such transformations not only made an entire sector of society (women) economically dependent on others and particular forms of social relations but also, through progressively isolation, lose political agency. But beyond the idea of the kitchen as an apparatus for the perpetuation of clichés, being aware that this type of domesticity is a construction can allow us to understand its reversibility or ability to change. Home values are always in permanent mutation, and today, those which deal with the kitchen are precisely the most capable of radically changing preset gender roles and domestic labor structures.
Integration ofD2Dwith Edge/Fog Computing
Authors: Zhu Zhaowei , Luo Xiliang , Wang Kunlun , Yang Yang 
Published: February 2020

AbstractWireless access points and nearby mobile devices usually possess some available computation and storage resources. In the prospective dense wireless networks, these resources could be sufficiently abundant due to a large number of devices. It is critical to investigate how to efficiently distribute the computation and storage burden of local equipment to nearby devices. The corresponding paradigm, proposed by Cisco, is called fog computing. Fog computing cannot survive without the support of ubiquitous communication, which appeals to high‐speed direct communications provided by device‐to‐device (D2D) techniques. This article will discuss the challenges and solutions in integrating D2D into fog computing.
Endosomal Confinement of Gold Nanospheres, Nanorods, and Nanoraspberries Governs Their Photothermal Identity and Is Beneficial for Cancer Cell Therapy
Authors: Plan Sangnier Anouchka , Van de Walle Aurore , Aufaure Romain , Fradet Magali , Motte Laurence , Guénin Erwann , Lalatonne Yoann , Wilhelm Claire 
Published: February 2020

AbstractGold nanoparticles can act as photothermal agents to generate local tumor heating and subsequent depletion upon laser exposure. Herein, photothermal heating of four gold nanoparticles and the resulting induced cancer cell death are systematically assessed, within extra‐ or intracellular localizations. Two state‐of‐the‐art gold nanorods are compared with small nanospheres (single‐core) and nanoraspberries (multicore). Heat generation is measured in water dispersion and in cancer cells, using lasers at wavelengths of 680, 808, and 1064 nm, covering the entire range used in photothermal therapy, defined as near infrared first (NIR‐I) and second (NIR‐II) windows, with NIR‐II offering more tissue penetration. When dispersed in water, gold nanospheres provide no significant heating, gold nanorods are efficient in NIR‐I, and only gold nanoraspberries are still heating in NIR‐II. However, in cells, due to endosomal confinement, all nanoparticles present an absorption red‐shift translating visible and NIR‐I absorbing nanoparticles into effective NIR‐I and NIR‐II nanoheaters, respectively. The gold nanorods then become competitive with the multicore nanoparticles (nanoraspberries) in NIR‐II. Similarly, once in cells, gold nanospheres can be envisaged for NIR‐I heating. Remarkably, nanoraspberries are efficient nanoheaters, whatever the laser applied, and the extra‐ versus intra‐cellular localization demonstrates treatment versatility.
A Cross‐Linked Interconnecting Layer Enabling Reliable and Reproducible Solution‐Processing of Organic Tandem Solar Cells
Authors: Liu Chao , Du Xiaoyan , Gao Shuai , Classen Andrej , Osvet Andres , He Yakun , Mayrhofer Karl , Li Ning , Brabec Christoph J. 
Published: February 2020

AbstractThe performance of tandem organic solar cells (OSCs) is directly related to the functionality and reliability of the interconnecting layer (ICL). However, it is a challenge to develop a fully functional ICL for reliable and reproducible fabrication of solution‐processed tandem OSCs with minimized optical and electrical losses, in particular for being compatible with various state‐of‐the‐art photoactive materials. Although various ICLs have been developed to realize tandem OSCs with impressively high performance, their reliability, reproducibility, and generic applicability are rarely analyzed and reported so far, which restricts the progress and widespread adoption of tandem OSCs. In this work, a robust and fully functional ICL is developed by incorporating a hydrolyzed silane crosslinker, (3‐glycidyloxypropyl)trimethoxysilane (GOPS), into poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), and its functionality for reliable and reproducible fabrication of tandem OSCs based on various photoactive materials is validated. The cross‐linked ICL can successfully protect the bottom active layer against penetration of high boiling point solvents during device fabrication, which widely broadens the solvent selection for processing photoactive materials with high quality and reliability, providing a great opportunity to continuously develop the tandem OSCs towards future large‐scale production and commercialization.