bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chinese Clinical Named Entity Recognition in Electronic Medical Records: Development of a Lattice Long Short-Term Memory Model With Contextualized Character Representations
Authors: Li Yongbin , Wang Xiaohua , Hui Linhu , Zou Liping , Li Hongjin , Xu Luo , Liu Weihai 
Published: August 2020

Background
Clinical named entity recognition (CNER), whose goal is to automatically identify clinical entities in electronic medical records (EMRs), is an important research direction of clinical text data mining and information extraction. The promotion of CNER can provide support for clinical decision making and medical knowledge base construction, which could then improve overall medical quality. Compared with English CNER, and due to the complexity of Chinese word segmentation and grammar, Chinese CNER was implemented later and is more challenging.

Objective
With the development of distributed representation and deep learning, a series of models have been applied in Chinese CNER. Different from the English version, Chinese CNER is mainly divided into character-based and word-based methods that cannot make comprehensive use of EMR information and cannot solve the problem of ambiguity in word representation.

Methods
In this paper, we propose a lattice long short-term memory (LSTM) model combined with a variant contextualized character representation and a conditional random field (CRF) layer for Chinese CNER: the Embeddings from Language Models (ELMo)-lattice-LSTM-CRF model. The lattice LSTM model can effectively utilize the information from characters and words in Chinese EMRs; in addition, the variant ELMo model uses Chinese characters as input instead of the character-encoding layer of the ELMo model, so as to learn domain-specific contextualized character embeddings.

Results
We evaluated our method using two Chinese CNER datasets from the China Conference on Knowledge Graph and Semantic Computing (CCKS): the CCKS-2017 CNER dataset and the CCKS-2019 CNER dataset. We obtained F1 scores of 90.13% and 85.02% on the test sets of these two datasets, respectively.

Conclusions
Our results show that our proposed method is effective in Chinese CNER. In addition, the results of our experiments show that variant contextualized character representations can significantly improve the performance of the model.
FORMULATION OPTIMIZATION AND EVALUATION OF FLURBIPROFEN EMULGEL
Authors: CHODANKAR DIKSHA S. , KUDCHADKAR SACHI S. , GUDE RAJASHREE S. , NAVTI PRERANA D. , SAWANT SANAM M. 
Published: August 2020

Objective: The objective of the present study was to formulate flurbiprofen (FLB) emulgel, evaluation of the formulations and the selection of an optimized formulation through in vitro drug release and drug content studies. Flurbiprofen is a non-steroidal anti-inflammatory drug (NSAID) requiring frequent administration and its chronic intake can lead to systemic side effects like gastric irritation and GI bleeding. The development of a dermal drug delivery system can overcome these side effects.
Methods: The emulgel formulations were produced using different combinations of oil and emulsifying agents. Carbopol 940 was used as a gelling agent. The prepared emulgels were evaluated for general appearance, pH, spreadability, extrudability, drug content, in vitro drug release, average globule size and viscosity.
Results: Optimized formulation F7 showed a better in vitro drug release compared to the marketed gel preparation. The stability study for the optimized formulation was carried out at 25 °C/60 % RH for 3 mo and the emulgel was found to be stable concerning the physical appearance, pH and drug content.
Conclusion: The study revolved around the formulation of emulgel containing Flurbiprofen for dermal delivery of the drug. Emulgel was formulated with the purpose to enhance the permeation of poorly water-soluble drug FLB. The study concluded that the optimized emulgel containing FLB exhibited better in vitro drug release profile compared to the marketed formulation.
BANANA PEEL FLAKES ALLEVIATE BLOOD GLUCOSE AND STRESS IN A DOSE-DEPENDENT MANNER
Authors: MELIALA ANDREANYTA , SUMIWI YUSTINA ANDWI ARI , NARWIDINA PARAMITA , RINI SRI LESTARI SULISTYO , SETYANINGSIH WIDIASTUTI 
Published: August 2020

Objective: This study aimed to evaluate the antidiabetic and antidepressant effects of banana peel flakes in streptozotocin-induced diabetic rats.
Methods: Twenty-five male Wistar rats were classified into five groups with different treatments. Groups I to IV were diabetic rats model groups that consumed only standard diet, standard diet containing 5%, 10%, and 20% of banana peel flakes, respectively. While group V was a healthy control group fed a standard diet. Immunohistochemistry staining was measured to examine serotonin expression in the colon and pancreas.
Results: The diabetic rats treated with 20% banana peel flakes had a lower blood glucose concentration (p<0.05) compared with diabetic control and showed a shorter duration of immobility time (p<0.05) than the healthy control. Additionally, compared with diabetic control, the diabetic rats treated with 5% banana peel flakes showed higher serotonin expression (p<0.05) in the colon. In contrast, serotonin expression in the pancreas did not show any significant difference (p>0.05).
Conclusion: The present study disclosed that the banana peel flakes provided an antidepressant effect in the diabetic rats model, which might occur through the mechanism of controlling blood glucose concentration.
DEVELOPMENT AND EVALUATION OF NOVEL ESTIMATION TECHNIQUES FOR IN VITRO DISSOLUTION STUDY AND VALIDATION PROTOCOL FOR ESCITALOPRAM AS ANTIDEPRESSANT DRUG AND THEIR FORMULATION
Authors: BAIRAGI SHRIRAM H. , GHOSH R. S. 
Published: August 2020

Objective: To develop and validate the RP-HPLC method and in vitro dissolution study for escitalopram as antidepressant drug and their formulation.
Methods: The chromatographic separation was done by using a C-18, 150 mm column and a mobile phase consisting of phosphate buffer (40%) and acetonitrile HPLC grade (60%). Detection was carried out at 211 nm with a flow rate of 1 ml/min with an injection of 20 μl. The method was validated with different parameters such as linearity, precision, accuracy, robustness, and limit of detection (LOD), the limit of quantification (LOQ) according to ICH guidelines.
Results: The linear calibration curve was obtained in the concentration range of 0-50 μg/ml and gave an average correlation factor 0.992. The retention time was observed at 2.96 min. The Minimum concentration level at which the analyte can be reliably detected (LOD) and quantified (LOQ) were found to be 0.03 and 0.09 µg/ml, respectively. The relative standard deviation of intra and the inter-day assay was found to be less than 2. The dissolution studies show moderate dissolution (23.4%) after 45 min, but it reaches a plateau after approximately 25 min.
Conclusion: This method was found to be simple, rapid and economic with less run time. The validated parameters manifest the method is reliable, linear, accurate and precise as well as robust with minor variations in chromatographic parameters. Therefore, the developed method can be applied for both routine analysis and quality control assay and it could be a very powerful tool to investigate the stability of escitalopram.
PREVALENCE AND CORRELATION OF CONTRACEPTIVE USE AMONG FEMALES IN JEDDAH, SAUDI ARABIA
Authors: BAGALAGEL ALAA 
Published: August 2020

Objective: The purpose of this study was to examine the prevalence of contraceptive use and the correlates of contraceptive use among females in Jeddah, Saudi Arabia. Moreover, it aimed to evaluate the knowledge about contraceptives and their use.
Methods: The study was a community-based, cross-sectional descriptive survey conducted in Saudi Arabia from 28 September 2015 to 10 December 2015.
Results: The current study showed that the most commonly used contraceptives were intrauterine devices (IUD’s) (29.1%), followed by male condoms (27.7%). Most of the participants, 47.6%, started using a contraceptive after giving birth to their first child. Nearby, 60% of participants used contraceptives without a prescription or medical advice. Only 13.7 % of participants sought the advice of a pharmacist about which contraceptive they should use, while 30.6% and 24.2% of participants choose their contraceptive based on general knowledge and relatives’ experiences, respectively. Around 80% of participants stated that they did not have any problem while buying contraceptives from pharmacies without a prescription.
Conclusion: Pharmacists and medical health providers need to fill this gap to improve the use of contraceptives.
Faktor yang Mempengaruhi Ibu Hamil Memilih Penolong Persalinan di Wilayah Kerja Puskesmas Malakopa Kabupaten Kepulauan Mentawai
Authors: Neti Desi Fitria , Waris Lukman , Yulianto Aris 
Published: August 2020

Abstrak
Kematian ibu dan anak masih menjadi masalah kesehatan. Risiko mengalami kematian ibu atau bayi bagi ibu melahirkan sangat dipengaruhi di mana seorang ibu hamil memilih penolong persalinan. Studi ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi ibu hamil dalam memilih penolong persalinan di wilayah kerja Puskesmas Malakopa Kabupaten Kepulauan Mentawai. Metode penelitian kuantitatif dengan desain potong lintang. Data dikumpulkan pada Puskesmas Malakopa Kabupaten Kepulauan Mentawai Provinsi Sumatrera Barat bulan Maret 2017. Teknik pengambilan sampel secara random sampling, data dianalisis dengan menggunakan SPSS. Pengumpulan data melalui observasi, wawancara, dan telaah dokumen. Hasil penelitian Ibu hamil di wilayah Puskesmas Malakopa yang memilih bersalin dengan tenaga kesehatan sebesar 62,9%, persalinan ditolong oleh tenaga non kesehatan sebesar 37,1%. Uji statistik menunjukkan tidak terdapat hubungan bermakna antara faktor internal dan eksternal pada kelompok ibu hamil terhadap pemilihan penolong persalinan. Untuk itu disarankan dalam meningkatkan cakupan persalinan nakes di wilayah kerja Puskesmas Malakopa Kabupaten Kepulauan Mentawai diperlukan perhatian kusus bagi tenaga kesehatan terhadap faktor yang mempengaruhi ibu hamil dalam memilih penolong persalinan.
Kata kunci: Ibu Hamil, Penolong Persalinan
Abstract
Maternal and child mortality is still becoming health problem. The risk of having a mother or baby’s death for the mother of childbirth is strongly influenced where a pregnant woman chooses a birth attendant. This study aimed to determine the factors that influence pregnant women in choosing birth attendants in the working area of Malakopa Health Center, Mentawai Islands District. This research is quantitative method with cross- sectional design. Data was collected at Malakopa Health Center, Mentawai Islands District, West Sumatera Province, in March 2017. The sampling technique was random sampling. Data was analyzed using SPSS. Collecting data through observation, interviews, and document review. The results of the study of pregnant women in the Malakopa Health Center area who chose to give birth with health workers were 62.9%, deliveries were assisted by non-health workers by 37.1%. The statistic test showed no significant relationship between internal and external factors in the group of pregnant women on the selection of birth attendants. It is recommended that in increasing coverage of health workers in the working area of the Malakopa Health Center, Mentawai District need special attention for health workers on factors that affect pregnant women in choosing birth attendants.
Keywords: Pregnant Women, Birth attendants
Prevalensi Psikosis di Indonesia berdasarkan Riset Kesehatan Dasar 2018
Authors: Idaiani Sri , Yunita Indri , Tjandrarini Dwi Hapsari , Indrawati Lely , Darmayanti Ika , Kusumawardani Nunik , Mubasyiroh Rofingatul 
Published: August 2020

Abstrak
Psikosis adalah gangguan jiwa yang memiliki prevalensi kecil dibandingkan gangguan jiwa lainnya tetapi mempunyai beban penyakit yang cukup tinggi. Tujuan analisis ini adalah untuk memperoleh prevalensi psikosis pada penduduk Indonesia secara nasional, per provinsi dan melihat sebaran psikosis antara perkotaan, perdesaan berdasarkan Riset Kesehatan Dasar (Riskesdas) 2018. Analisis ini merupakan analisis lanjut Riskesdas dilaksanakan di 34 provinsi, 514 kabupaten/kota pada bulan Juli 2018. Jumlah blok sensus 29.824 dengan respon rate 99,41%, jumlah rumah tangga dikunjungi dan diwawancara 282.654 dengan respon rate 95,58%. Enumerator bertanya kepada kepala keluarga atau yang mewakilinya mengenai adakah anggota rumah tangga (ART) di rumah tersebut yang pernah atau sedang mengalami gangguan jiwa psikosis dan berapa banyak jumlahnya. Analisis dilakukan dengan perangkat statistik SPSS versi 22 dengan metode complex sample. Berdasarkan Riskesdas 2018, didapatkan estimasi prevalensi orang yang pernah menderita psikosis di Indonesia sebesar 1,8 per 1000 penduduk. Prevalensi antar provinsi berkisar 0.9 sampai 3.5 per 1000 penduduk. Prevalensi psikosis lebih tinggi di perdesaan dibandingkan di perkotaan (p=0,099).
Kata kunci: Riskesdas 2018, psikosis, prevalensi
Abstract
Psychosis is a mental disorder that has a small prevalence compared to other mental disorders but it has a fairly high burden of disease. The purpose of this analysis is to obtain the national, provincial prevalence of psychosis and to compare the prevalence between urban and rural regions in Indonesia based on Basic Health Research (Riskesdas) 2018. This is an advance analysis. Riskesdas was implemented in July 2018 in 34 provinces and 514 regencies/cities. A total of 29,824 census blocks with a response rate of 99.41%, as many as 282.654 households visited and interviewed with a response rate of 95.58%. The enumerator interviewed the head of the family or his representative regarding the existence of household members (ART) in the house who had or were experiencing psychosis and how many of them. The analysis was carried out with SPSS version 22 using the complex sample method. Based on Riskesdas 2018, an estimated prevalence of people who have suffered psychosis in Indonesia is 1.8 per 1000 population. The prevalence between provinces ranges from 0.9 to 3.5 per 1000 population. The prevalence is higher in rural than urban area (p=0.099).
Keywords: Riskesdas 2018, psychosis, prevalence
Faktor-Faktor yang Berhubungan dengan Pemeriksaan Inspeksi Visual Asam Asetat (IVA) di Puskesmas Cibinong Tahun 2019
Authors: Pebrina Reffi Jordania , Kusmiyanti Margaretha , Surianto Fulgensius 
Published: August 2020

Abstrak
Kanker serviks merupakan peringkat enam penyebab utama kematian wanita dan peringkat dua kematian pada wanita berusia 15-44 tahun. Di Asia deteksi dini penyakit kanker serviks dilakukan melalui pemeriksaan Inspeksi Visual Asam Asetat (IVA). Penelitian ini bertujuan untuk menganalisis faktor-faktor yang berhubungan dengan pemeriksaan inspeksi visual asam asetat (IVA) di Puskesmas Cibinong Tahun 2019. Rancangan penelitian menggunakan desain cross-sectional pada 44 responden pasien KIA di Puskesmas Cibinong. Pengumpulan data di lakukan pada bulan April 2019 dengan menggunakan kuesioner dengan variabel umur, pendidikan, pekerjaan, pengetahuan, dukungan keluarga dan dukungan petugas kesehatan yang telah di uji validitas dan reliabilitas. Analisis data menggunakan uji chi square dan kendall’s tau b. Hasil menunjukkan bahwa umur (p-value 0,008) dan dukungan petugas kesehatan (p-value 0,015) berhubungan bermakna dengan pemeriksaan IVA dan faktor yang tidak berhubungan dengan pemeriksaan IVA ialah pendidikan, pekerjaan, pengetahuan dan dukungan keluarga. Hal tersebut menunjukkan perlunya peningkatan program promosi kesehatan, sosialisasi dan konseling kepada para ibu yang berkunjung ke Puskesmas Cibinong.
Kata kunci: wanita, kanker serviks, Inspeksi Visual Asam Asetat (IVA)
Abstract
Cases of cervical cancer, as ranked 6th leading cause of female death and rank 2nd death in women aged 15-44 years. In Asia cervical cancer early screening or detection programs is through Visual Inspection with Acetic Acid (VIA). The study aims to analyze factors related to the examination of Visual Inspection with Acetic Acid (VIA) in Cibinong Health Center’s in 2019. This is a cross-sectional study with a sample of 44 respondents patient KIA in Cibinong Health Center’s. Data collection was taken through filling a set of questionnaires in April 2019 which have been tested for validity and reliability. Analysis performed by chi-square and Kendall’s tau b. The analysis shows age (p-value 0,008) and health practitioner’s support (p-value 0,015) are significantly related to examination of VIA and factor is not related to examination of VIA is education, job, knowledge and family support. It evidence to improve health promotion programs socialization and counseling for mothers who visit the Cibinong Health Center.
Keywords: women, cervical cancer, Visual Inspection Acetic Acid (VIA)
Accountant as Digital Innovator: Roles and Competencies in the Age of Automation
Authors: Kokina Julia , Gilleran Ruth , Blanchette Shay , Stoddard Donna 
Published: August 2020

SYNOPSIS
In this paper we explore how Robotic Process Automation (RPA) is changing the work of accountants, identify the roles that accountants will play in their organizations' digital transformations, and categorize the skills and competencies that accountants will need to develop in order to successfully work alongside their digital colleagues. We employ a multiple case study methodology and collect interview data from eight organizations undergoing RPA implementations for their accounting and finance tasks. Our analysis reveals that accountants play important roles as Identifiers, Explainers, Trainers, Sustainers, and Analyzers of their organizations' automation initiatives. To prepare to undertake these five roles, accountants will need to acquire new technical skills. Therefore, the paper concludes with a mapping of the skills needed for each role that the accountant is expected to play in RPA implementations.
The Future of Assurance in Capital Markets: Reclaiming the Economic Imperative of the Auditing Profession
Authors: Knechel W. Robert 
Published: August 2020

SYNOPSIS
Efficient capital markets rely on a continuous supply of reliable, timely, and audited information. The economic value of an audit derives from the reduction in risk of erroneous or manipulated information. Traditionally, the auditing has focused on annual financial reports. Given the speed of information creation and dissemination, the role of auditors may need to adapt. There are three areas in which auditors might help improve information quality: (1) non-GAAP earnings; (2) ESG reporting; and (3) cybersecurity risks disclosures. To provide assurance over these types of information, audit firms need to identify the appropriate subject matter for assurance, obtain expertise to provide assurance, develop a verification process, and commit to a system of organizational support. Multidisciplinary practices have the potential to provide many types of expanded assurance. However, success is not inevitable, and market, social, and regulatory forces will have much to say about the emergence of new assurance initiatives.
Bringing Scholarly Data Analytics Knowledge Using Emerging Technology Tools in Accounting into Classrooms: A Bibliometric Approach
Authors: Liu Qi , Chiu Victoria , Muehlmann Brigitte W. , Baldwin Amelia Annette 
Published: August 2020

ABSTRACT
This study aims to help educators advance the integration of scholarly data analytics knowledge using emerging technology tools in accounting throughout the curriculum, thereby contributing to teaching for future-oriented practice. It provides an analysis of 215 peer-reviewed data analytics contributions including 16 classroom applications published from 2004 to 2018 in the six journals that have largely served as destinations of technology-related accounting research of all kinds and are commonly referred to as AIS journals, which are the Journal of Information Systems, International Journal of Accounting Information Systems, Journal of Emerging Technologies in Accounting, International Journal of Digital Accounting Research, AIS Educator Journal and Intelligent Systems in Accounting, Finance and Management. Accounting educators find detailed guidance on which peer-reviewed data analytics research contributions and tools are available to be integrated into financial and managerial accounting, auditing, accounting information systems, and tax courses.
James on the stream of language: with some remarks on his influence on Wittgenstein
Authors: Dreon Roberta 
Published: August 2020

Este artigo sustenta uma leitura do capítulo “Stream of Thought” em The Principles of Psichology segundo o qual William James não formulou uma ideia de significados linguísticos como sentimentos privados que ocorrem dentro da mente do falante, ao contrário, criticava o hábito de, basicamente, considerar a linguagem como uma associação de nomes, devido às consequências ilusórias dessa suposição ao nosso entendimento do pensamento como resultante, principalmente, da soma das suas partes discretas. James sugere a possibilidade de adoção de uma abordagem diferente da linguagem por considerar seus aspectos contínuos, relacionais ou transitivos, em vez de focar exclusivamente nos elementos substantivos. Ele parece convidar seus leitores a adotar uma atitude voltada para a linguagem complementando sua própria visão holística do pensamento como relações contínuas e envolventes. A autora explora a afirmação de que James considerava duas atitudes diferentes para a linguagem (GAVIN, 1992, p. 69): uma abordagem mais crítica e uma disposição que está atenta à dinâmica, contextual e formação corpórea do significado das palavras. Esta leitura baseia-se na ideia, bem como outras, de que The Principles teve uma influência positiva em Wittgenstein, em vez de uma mera crítica—uma interpretação sustentada por um grupo de estudiosos recentes (BONCOMPAGNI, 2012a, 2012b; GOODMAN, 2002; JACKMAN, 2006, 20017; e SANFELIX-VIDARTE, 2016).
Yogic Interventions for Psycho-Physical Well-Being Under Covid-19 Times & After
Authors: Malik Nishtha , Sharma Aditi 
Published: August 2020

Health indeed is Wealth. The Corona Virus Pandemic has impacted the best health-care systems world-wide; even as the world grapples with the massive loss of human life causing pain to millions. The Pandemic is no more just a medical health challenge; it has thrown up spiritual and emotional challenges as it is affecting our belief system.
Prevention is Better than Cure is the mantra. Since, there is no allopathic medicine solution available; people are adopting various measures like social distancing and personal sanitization. There is an urgent need to assist the individuals to take all the preventive measures possible to boost their immunity, improve the respiratory system, and lessen the anxiety, stress, and depression. It can be difficult to not feel anxiety and sometimes panic over the coronavirus outbreak, with the onslaught of updates on news and social media.
Yoga has emerged as the perfect tool that an individual can follow to establish physical, mental, and spiritual balance to develop robust health and combat physical and emotional challenges. Yoga offers another path, a fresh perspective with which to deal with events that are beyond our control. The different asanas of yoga can help us to prevent COVID-19 by boosting our immune system and managing the stress that one is going through in this time of uncertainty.
This study tries to specifically evaluate the impact of the preventive measures undertaken through Yoga practice. 126 respondents from different states of India were requested to perform yoga daily for 30 days. Significant changes were observed and are mentioned in detail.