bluuebunny/crossref_metadata_2025_split huggingface dataset:
What stops revenge taking? Effects of observed emotional reactions on revenge seeking
Authors: Eder Andreas B. , Mitschke Vanessa , Gollwitzer Mario 
Published: March 2020

AbstractWhat reaction stops revenge taking? Four experiments (total N = 191) examined this question where the victim of an interpersonal transgression could observe the offender's reaction (anger, sadness, pain, or calm) to a retributive noise punishment. We compared the punishment intensity selected by the participant before and after seeing the offender's reaction. Seeing the opponent in pain reduced subsequent punishment most strongly, while displays of sadness and verbal indications of suffering had no appeasing effect. Expression of anger about a retributive punishment did not increase revenge seeking relative to a calm reaction, even when the anger response was disambiguated as being angry with the punisher. It is concluded that the expression of pain is the most effective emotional display for the reduction of retaliatory aggression. The findings are discussed in light of recent research on reactive aggression and retributive justice.
Data‐Driven Urbanism: The Balance Between Spatial Intelligence and Design Craftsmanship
Authors: He Shan 
Published: March 2020

AbstractThe sheer quantity of data about how people interact – spatially and digitally – and travel through cities requires a range of computerised geospatial visualisation tools. Shan He is a coder, designer, architect and data artist. She is also founder of Uber's data visualisation team and inventor of Uber's kepler.gl software. Here she draws our attention to the varying ways such data can be presented to facilitate quick and easy human understanding.
Smart Who? Collective Intelligence Urban Design Models
Authors: Markopoulou Areti 
Published: March 2020

AbstractWhilst big data accumulates at exponential rates, its analysis is currently linear. As architect, urban technologist and Academic Director at the Institute for Advanced Architecture of Catalonia (IAAC) in Barcelona Areti Markopoulou points out, at the moment inhabitants of cities are data‐captured, yet no circular feedback occurs to make them aware of their actions at the personal and immediate level. She evokes ideas developed by cyberneticians decades ago as the basis for co‐created urban design models produced by merging artificial with crowd intelligence.
Catalyst‐Free Electrosynthesis of Benzimidazolones through Intramolecular Oxidative C−N Coupling
Authors: Li Jiang‐Sheng , Yang Pan‐Pan , Xie Xin‐Yun , Jiang Si , Tao Li , Li Zhi‐Wei , Lu Cui‐Hong , Liu Wei‐Dong 
Published: March 2020

AbstractThe electrochemical synthesis of N, N’‐disubstituted benzimidazolones from ureas through an intramolecular anodic dehydrogenative N−H/C−H coupling has been developed. The reaction undergoes under the undivided electrolysis conditions and obviates the need for any catalysts and chemical oxidants.magnified image
Evaluation of serum neutrophil gelatinase‐associated lipocalin in older patients with chronic kidney disease
Authors: Guo Lulu , Zhu Bei , Yuan Haichuan , Zhao Weihong 
Published: March 2020

AbstractObjectiveChronic kidney disease (CKD) is a major health‐care burden all over the world, and aging is an important risk factor for end‐stage renal disease (ESRD). Neutrophil gelatinase‐associated lipocalin (NGAL) has been confirmed as a novel marker for early diagnosis of acute kidney injury. Other studies have found that NGAL takes part in the mechanisms of CKD progression. The aim of this study was to evaluate the expression of serum NGAL in CKD, particularly in elderly patients who rapidly progressed to end‐stage renal failure.MethodsSerum NGAL, cystatin C, creatinine, urea, and other factors were evaluated in a cohort of 160 CKD patients (mean age 75.29 ± 12.08 years) with various etiologies.ResultsSerum NGAL was closely related to cystatin C, creatinine, urea, and estimated glomerular filtration rate (eGFR). Special correlations between NGAL and, respectively, anemia and hypoalbuminemia were also found. The cutoff value of NGAL was calculated from Stage 2 to Stage 5. Receiver–operator curve analysis showed good area under the curve (>0.8) and high sensitivity (> 70%) on the cutoff value of NGAL. The NGAL levels increased progressively with the increasing of 2‐ and 5‐year risk of ESRD using the Kidney Failure Risk Equations (KFRE).ConclusionIn elderly patients with CKD, serum NGAL reflects renal impairment and presents a strong and independent risk marker for progression of ESRD.
Characteristics of early‐onset pancreatic cancer and its association with familial pancreatic cancer and hereditary pancreatic cancer syndromes
Authors: Eguchi Hidetoshi , Kobayashi Shogo , Gotoh Kunihito , Noda Takehiro , Doki Yuichiro 
Published: March 2020

AbstractThe incidence of pancreatic cancer is high among those in their sixties to seventies but low in those in their fifties or younger. Although there is no unified definition regarding the age of early‐onset pancreatic cancer, previously published reports suggest that, compared to later‐onset pancreatic cancer patients, early‐onset pancreatic cancer patients tend to be detected at advanced stages and thus have poor prognoses, but they do not show significantly higher rates of patients with genetic factors. On the other hand, it has been reported that patients with familial pancreatic cancer and hereditary pancreatic cancer syndromes often develop pancreatic cancer at a young age. The broad definition of familial pancreatic cancer is pancreatic cancer in patients who have two or more first‐degree relatives with pancreatic cancer; whereas the narrow definition of familial pancreatic cancer is the broad definition of familial pancreatic cancer, while excluding those with inherited tumor syndromes. Hereditary tumors developing pancreatic cancer include hereditary pancreatitis, hereditary breast and ovarian cancer, Peutz‐Jeghers syndrome, familial atypical multiple mole melanoma syndrome, familial adenomatous polyposis, and hereditary non‐polyposis colorectal cancer, all of which are autosomal dominant hereditary diseases. This study reviews the clinical characteristics of early‐onset pancreatic cancer and its association with familial pancreatic cancer and hereditary pancreatic cancer syndromes.
Temperature‐dependent vapor–liquid equilibria and solvation free energy estimation from minimal data
Authors: Chung Yunsie , Gillis Ryan J. , Green William H. 
Published: March 2020

AbstractWe present a new strategy to estimate the temperature‐dependent vapor–liquid equilibria and solvation free energies of dilute neutral molecules based on only their estimated solvation energy and enthalpy at 298 K. These two pieces of information coupled with matching conditions between the functional forms developed by Japas and Levelt Sengers for near critical conditions and by Harvey for low and moderate temperature conditions allow the fitting of a piecewise function that predicts the temperature‐dependent solvation energy for dilute solutes up to the critical temperature of the solvent. If the Abraham and Mintz parameters for the solvent and solute are available or can be estimated from group contributions, this method requires no experimental data and can still provide accurate estimates with an error of about 1.6 kJ/mol. This strategy, which requires minimal computational resources, is shown to compare well with other methods of temperature‐dependent solvation free energy prediction.
Synthesis of Bio‐Based Cyclic Carbonates Using a Bio‐Based Hydrogen Bond Donor: Application of Ascorbic Acid to the Cycloaddition of CO2 to Oleochemicals
Authors: Natongchai Wuttichai , Pornpraprom Suriyaporn , D' Elia Valerio 
Published: March 2020

AbstractOleochemicals such as functionalized fatty acid esters and vegetable oils are classes of renewably sourced compounds that are increasingly attracting attention in sustainable chemistry as replacement for fossil‐fuel based chemicals. The possibility of coupling CO2 with epoxidized fatty acids esters (EFAEs) and epoxidized vegetable oils (EVOs) to afford compounds that are attractive as additives or chemical intermediates in the synthesis of non‐isocyanate polyhydroxyurethanes (NIPU) can conjugate highly sought‐after CO2 valorization with the exploitation of bio‐based substrates. In this context, there have been very few attempts to employ organocatalytic hydrogen bond donors (HBDs) in the cycloaddition reaction of CO2 to EFAEs and EVOs and no studies focusing on bio‐based and readily available HBDs. In this work we show that ascorbic acid is an efficient HBD for the cycloaddition of CO2 to EFAEs and EVOs under mild reaction conditions of temperature (80–100 °C) and pressure (5–10 bar) that could be applied to several kinds of substrates (monounsaturated EFAEs, polyunsaturated EFAEs and EVOs). In all cases, the formed by‐products (ketones, allylic alcohols, cyclic ethers etc.) were identified and the reaction conditions were tuned in order to obtain the target carbonates, generally, in high yields and selectivity.
Ethynylation of Cysteine Residues: From Peptides to Proteins in Vitro and in Living Cells
Authors: Tessier Romain , Nandi Raj Kumar , Dwyer Brendan G. , Abegg Daniel , Sornay Charlotte , Ceballos Javier , Erb Stéphane , Cianférani Sarah , Wagner Alain , Chaubet Guilhem , Adibekian Alexander , Waser Jerome 
Published: March 2020

AbstractCurrent approaches to introduce terminal alkynes for bioorthogonal reactions into biomolecules still present limitations in terms of either reactivity, selectivity, or adduct stability. We present a method for the ethynylation of cysteine residues based on the use of ethynylbenziodoxolone (EBX) reagents. The acetylene group is directly introduced onto the thiol group of cysteine and can be used for copper‐catalyzed alkyne‐azide cycloaddition (CuAAC) without further processing. Labeling proceeded with reaction rates comparable to or higher than the most often used iodoacetamide on peptides or maleimide on the antibody trastuzumab, and high cysteine selectivity was observed. The reagents were also used in living cells for cysteine proteomic profiling and displayed improved coverage of the cysteinome compared to previously reported iodoacetamide or hypervalent iodine reagents. Fine‐tuning of the EBX reagents allows optimization of their reactivity and physical properties.
Submicron laser‐textured vents for self‐cleaning injection molds
Authors: Sorgato Marco , Zanini Filippo , Masato Davide , Lucchetta Giovanni 
Published: March 2020

AbstractClogging of venting slots in injection molds is a common maintenance problem caused by the degradation and the accumulation of gaseous and volatiles by‐products of polymer melting. In this work, the effect of laser‐induced periodic surface structures on the self‐cleaning properties of venting slots is investigated. The degradation of poly(ethylene terephthalate) (PET) over different surfaces is characterized by reproducing the mechanisms that occurs in mold cavities when the air is pushed through the venting channel. An imaging technique is developed for the quantification of the sediment that deposits on sample surfaces due to condensation of by‐products of PET melting. The experimental results indicate that the use of a multiscale texture minimizes the deposition of residues on the vent surface reducing it from 17.2 to 3.1%. A linear dependency between contact angle and clogging ratio indicates the efficacy of the model that explains vent self‐cleaning properties considering their wetting properties.
Nano ZrO2 reinforced cellulose incorporated polyethylmethacrylate/polyvinyl alcohol composite films as semiconducting packaging materials
Authors: Prusty Kalyani , Swain Sarat K. 
Published: March 2020

AbstractA simple in situ polymerization process is used to synthesize nanocomposite films with incorporation of cellulose and nano ZrO2 (PEMA/PVA‐C@ZrO2). The change in structural, morphological, and functional properties are noticed due to combine effect of cellulose and zirconia which is studied by FTIR, XRD, XPS, FESEM, HRTEM, DLS, and AFM. The distribution of particle in the film is determined from dynamic light scattering (DLS). It is found that, dielectric permittivity is increased with percolation at 3 wt% of the nano ZrO2. Further, the dielectric permittivity (ε') value is found to be 110 at 1 Hz with a low dielectric loss (Tan δ = 1.74) and an optimum dielectric permittivity is 172 at 1 Hz for 4 wt% loading of nano ZrO2. Mechanical and thermal characteristics of the as‐synthesized films are improved due to interfacial adhesion between zirconia and polymeric matrix. The chemical resistance, biodegradable characteristics, and refractive index of the nanocomposite films are also measured. It is noticed that, the barrier properties are increased by 20‐folds due to the synergistic combination of nano ZrO2 and cellulose with polymeric matrix. The enhancement in barrier properties with improved dielectric permittivity can enable the as‐synthesized films for semiconducting packaging applications.
Proteome analysis of male accessory gland secretions in Leucinodes orbonalis Guenee (Lepidoptera: Crambidae), a Solanum melongena L. pest
Authors: Saraswathi Saraswathi , Chaitra B. S. , Tannavi Kiran , Mamtha R. , Sowrabha R. , Rao Karthik V. , Doddamane Manjulakumari 
Published: March 2020

AbstractMale accessory gland (MAG) proteins are transferred along with the sperm to females at the time of mating and have diverse effects on female reproductive physiology in a wide range of insects. In this study, we sought to identify the MAG proteins in Leucinodes orbonalis Guenee, a Solanum melongena L. pest, by analyzing the MAG proteins of virgin and mated male moths by nano‐LC‐ESI‐MS/MS techniques. A total of 142 and 131 proteins in virgin and mated males were identified, respectively, among which 17 (12.0%) and 10 (7.6%) proteins were found to show secretory signals in virgin and mated males, respectively. These secretory proteins were shown to be involved in several biological processes in insects, including egg development, sperm‐related functions/capacitation, defense, metabolism, and protein chaperoning. To the best of our knowledge, this is the first study to perform a proteome analysis of the MAG proteins of L. orbonalis, and offers an opportunity for further investigation of the functions of these proteins. In insects, certain MAG proteins are known to inhibit mating whereas others accelerate egg‐laying. Therefore, the identification of these proteins in L. orbonalis may be useful for pest control.
Anthraquinones: Versatile Organic Photocatalysts
Authors: Cervantes‐González Javier , Vosburg David A. , Mora‐Rodriguez Salma E. , Vázquez Miguel A. , Zepeda L. Gerardo , Villegas Gómez Clarisa , Lagunas‐Rivera Selene 
Published: March 2020

AbstractAnthraquinones (AQs) constitute the largest group of natural pigments, are commonly found in dyes, and are widely used in the textile industry due their photostability. They combine high absorptivity in the visible region with high excited‐state reduction potentials, making them effective acceptors of electrons and hydrogen atoms. AQs can be employed as organic catalysts in photooxidation reactions as well to produce reactive oxygen species (ROS). All these methods feature green chemistry aspects such as avoiding heavy metals, reducing waste, using inexpensive reagents, employing environmentally low‐impact solvents, and oxidizing with O2. This review covers the application of AQs in photoredox catalysis.
Shaping Electroluminescence with a Large, Printed Bipolar Electrode Array: Solid Polymer Electrochemical Cells with Over a Thousand Light‐Emitting p–n Junctions
Authors: Hu Shiyu , Gao Jun 
Published: March 2020

AbstractThe electroluminescence from a solid polymer light‐emitting electrochemical cell typically originates from a single, narrow p‐n or p‐i‐n junction. The bulk of the active material is non‐emitting and must be doped before an emitting junction is formed. Here, we show that the doping and emission profiles of a planar cell can be drastically altered with the introduction of a large printed array of ink‐jet‐printed bipolar electrodes. Redox doping reactions induced at the wireless bipolar electrodes led to the simultaneous formation of over a thousand highly emissive p‐n junctions uniformly distributed throughout the active layer of the large planar cell. The multi‐junction cell achieved an eightfold increase in light‐emitting area, a 14‐fold increase in peak current and ten times faster response speed compared to a single‐junction cell. Moreover, a giant open‐circuit voltage of approximately 35 V was observed when the doped cell was allowed to discharge. Here, bipolar electrochemistry offers a simple and yet elegant solution to engineer a better light‐emitting electrochemical cell.
Electrochemical C−H Functionalization of (Hetero)Arenes—Optimized by DoE
Authors: Dörr Maurice , Röckl Johannes L. , Rein Jonas , Schollmeyer Dieter , Waldvogel Siegfried R. 
Published: March 2020

AbstractA novel approach towards the activation of different arenes and purines including caffeine and theophylline is presented. The simple, safe and scalable electrochemical synthesis of 1,1,1,3,3,3‐hexafluoroisopropanol (HFIP) aryl ethers was conducted using an easy electrolysis setup with boron‐doped diamond (BDD) electrodes. Good yields up to 59 % were achieved. Triethylamine was used as a base as it forms a highly conductive media with HFIP, making additional supporting electrolytes superfluous. The synthesis was optimized using Design of Experiment (DoE) techniques giving a detailed insight to the significance of the reaction parameters. The mechanism was investigated by cyclic voltammetry (CV). Subsequent transition metal‐catalyzed as well as metal‐free functionalization led to interesting motifs in excellent yields up to 94 %.
Reactivity of Cobalt‐Fullerene Complexes towards Deuterium
Authors: Vanbuel Jan , Germán Estefanía , Libeert Guillaume , Veys Koen , Moens Janni , Alonso Julio A. , López María J. , Janssens Ewald 
Published: March 2020

AbstractThe adsorption of molecular deuterium (D2) onto charged cobalt‐fullerene‐complexes ConC60+ (n=1–8) is measured experimentally in a few‐collision reaction cell. The reactivity is strongly size‐dependent, hinting at clustering of the transition metal atoms on the fullerenes. Formation and desorption rate constants are obtained from the pressure‐dependent deuterogenation curves. DFT calculations indeed find that this transition metal clustering is energetically more favorable than decorating the fullerene. For n=1, D2 is predicted to bind molecularly and for n=2 dissociative and molecular configurations are quasi‐isoenergetic. For n=3–8, dissociation of D2 is thermodynamically preferred. However, reaching the ground state configuration with dissociated deuterium on the timescale of the experiment may be hindered by dissociation barriers.
Retracted publications and their citation in dental literature: A systematic review
Authors: Rapani Antonio , Lombardi Teresa , Berton Federico , Del Lupo Veronica , Di Lenarda Roberto , Stacchi Claudio 
Published: March 2020

AbstractObjectivesThe present systematic review aimed to perform an in‐depth analysis of the different features of retracted publications in the dental field.Material and methodsThis review has been recorded in the PROSPERO database (CRD42017075634). Two independent reviewers performed an electronic search (Pubmed, Retraction Watch) for retracted articles in dental literature up to December 31, 2018.Results180 retracted papers were identified, the first published in 2001. Retractions increased by 47% in the last four‐year period (2014–2018), when compared with 2009–2013 (94 and 64 retracted publications, respectively). Author misconduct was the most common reason for retraction (65.0%), followed by honest scientific errors (12.2%) and publisher‐related issues (10.6%). The majority of retracted research was conducted in Asia (55.6%), with 49 papers written in India (27.2%). 552 researchers (89%) are listed as authors in only one retracted article, while 10 researchers (1.6%) are present in five or more retracted publications. Retracted articles were cited 530 times after retraction: the great majority of these citations (89.6%) did not consider the existence of the retraction notice and treated data from retracted articles as reliable.ConclusionsRetractions in dental literature have constantly increased in recent years, with the majority of them due to misconduct and fraud. The publication of unreliable research has many negative consequences. Studies derived from such material are designed on potentially incorrect bases, waste funds and resources, and most importantly, increase risk of incorrect treatment for patients. Citation of retracted papers represents a major issue for the scientific community.
β‐Glucuronidase‐ and OATP2B1‐mediated drug interaction of scutellarin in Dengzhan Xixin Injection: A formulation aspect
Authors: Shi Jinxin , Sun Chengpeng , Huang Huilian , Lin Wenhui , Gao Jian , Lin Yanhe , Zhang Zhanjun , Huo Xiaokui , Tian Xiangge , Yu Zhenlong , Zhang Baojing , Ma Xiaochi 
Published: March 2020

AbstractScutellarin is the major and active constituent of Dengzhan Xixin Injection (DZXX), a traditional Chinese medicine prepared from the aqueous extract of Erigeron breviscapus and widely used for the treatment of various cerebrovascular diseases in clinic. In present study, the possible pharmacokinetic differences of scutellarin after intravenous administration of scutellarin alone or DZXX were explored. Additional, the potential roles of β‐glucuronidase (GLU) and OATP2B1 in drug–drug interaction (DDI) between scutellarin and constituents of DZXX were further evaluated in vitro. The plasma concentration, urinary and biliary excretion of scutellarin in rats after administration of DZXX, were significantly higher than those received scutellarin, while pharmacokinetic profile of Apigenin 7‐O‐glucuronide (AG) in rats was similar no matter AG or DZXX group. Furthermore, higher concentration in brain and plasma, however, lower level of scutellarin in intestine were observed after intravenous administration of DZXX. Finally, AG and caffeoylquinic acid esters were found to significantly inhibit GLU and OATP2B1 in vitro, which might explain, at least in part, the pharmacokinetic DDI between scutellarin and other chemical constituents in DZXX. The findings provided deep insight into the prescription‐formulating principle in DZXX for treating the cerebrovascular diseases.
Covid‐19 and diabetes mellitus: unveiling the interaction of two pandemics
Authors: Maddaloni Ernesto , Buzzetti Raffaella 
Published: March 2020

AbstractA novel RNA betacoronavirus causing coronavirus disease 2019 (Covid‐19) has now been declared pandemic disease by WHO. Guo et al published the first report of biochemical features in patients with diabetes and the further risk that this disease can determine to the progression of Covid‐19. Among different cytokines found significantly higher in patients with diabetes compared to those without, Interleukin‐6 (IL‐6), which is already increased in conditions of chronic inflammation, may play a more deleterious role in Covid‐19 infection. Targeting the overexpression of Il‐6 effects with a monoclonal antibody against IL‐6 receptor or using Janus Kinase inhibitors may be particularly helpful for treatment of Covid‐19 pneumonia in diabetes.