bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding intrinsic challenges to STEM instructional practices for Chinese teachers based on their beliefs and knowledge base
Authors: Dong Yan , Wang Jing , Yang Yunying , Kurup Premnadh M. 
Published: September 2020

Abstract
Background
China has great student participation in STEM education. Chinese society has a progressive and positive attitude towards STEM as it is considered to provide more opportunities in life. Teachers play a vital role in the success of any STEM program in K-12 schools. However, teachers are facing instructional challenges because of the interdisciplinary nature of the STEM curriculum and the current typical school structure. The success of the STEM programs depends on teachers’ beliefs and their knowledge in adapting to instructional implementation of STEM concepts.

Results
The data (n = 216) was collected from STEM primary and secondary teachers from 25 provinces in mainland China. Exploratory factor analysis (EFA) was applied, and Pearson’s correlation analysis was used to examine the correlation between Chinese STEM teachers’ beliefs, knowledge, implementation, and the intrinsic challenges of STEM education; t tests and analysis of variance (ANOVA) were performed to ascertain whether there were differences. The structural equation model (SEM) was applied to identify interrelationships. The results indicated that Chinese STEM teachers encounter higher-level intrinsic challenges to instructional implementations based on their beliefs and knowledge. Teachers who utilize their experience of teaching science as their main discipline and then attempt to integrate STEM using mathematics and engineering are likely to encounter higher-level intrinsic challenges in implementation.

Conclusion
The intrinsic challenges perceived by Chinese teachers in the practice of STEM education can be predicted by their beliefs and knowledge base. Teachers who understand the nature and pedagogy of STEM education are more likely to encounter lower-level intrinsic challenges of STEM teaching, while teachers who utilize their main discipline when conducting integrated STEM learning activities through modeling based on science, technology, engineering, and mathematical problem situations are more likely to encounter higher-level intrinsic challenges. This study also reveals that there are some significant differences in the level of STEM teachers’ beliefs, knowledge base, instructional practice, and their intrinsic challenges based on their teaching grade, seniority, and experience of STEM training and teaching.
Feasibility and acceptability of a televideo physical activity and nutrition program for recent kidney transplant recipients
Authors: Gibson Cheryl A. , Gupta Aditi , Greene J. Leon , Lee Jaehoon , Mount Rebecca R. , Sullivan Debra K. 
Published: September 2020

Abstract
Background
Post-transplant weight gain affects 50–90% of kidney transplant recipients adversely affecting survival, quality of life, and risk for diabetes and cardiovascular disease. Diet modification and physical activity may help prevent post-transplant weight gain. Methods for effective implementation of these lifestyle modifications are needed. The objective of this study is to assess the feasibility and acceptability of a remotely delivered nutrition and physical activity intervention among kidney transplant recipients. Secondary aims were to estimate the effectiveness of the intervention in producing changes in physical activity, qualify of life, fruit and vegetable intake, and consumption of whole grains and water from baseline to 6 months.

Methods
A randomized controlled study for stable kidney transplant recipients between 6 and 12 months post-transplantation was conducted. Participants were randomly assigned 1:1 to a technology-based, lifestyle modification program (intervention) or to enhanced usual care (control).

Results
The first 10 kidney transplant recipients screened were eligible and randomized into the intervention and control groups with no significant between-group differences at baseline. Health coaching attendance (78%) and adherence to reporting healthy behaviors (86%) were high. All participants returned for final assessments. The weight in controls remained stable, while the intervention arm showed weight gain at 3 and 6 months. Improvements were found for physical activity, quality of life, and fruit and vegetable intake in both groups. All participants would recommend the program to other transplant recipients.

Conclusions
Our data suggest that a remotely delivered televideo nutrition and physical activity intervention is feasible and valued by patients. These findings will aid in the development of a larger, more prescriptive, randomized trial to address weight gain prevention.

Trial registration
Clinicaltrials.gov Identifier NCT03697317. Retrospectively registered on October 5, 2018.
Assessment of cervical and ocular vestibular evoked myogenic potentials in migraine patients
Authors: Elmoazen Doaa , Kozou Hesham , Mekky Jaidaa , Ghanem Dalia 
Published: September 2020

Abstract
Background
Patients suffering from vestibular migraine (VM) are known to have various vestibular test abnormalities interictally and ictally. Recently, vestibular evoked myogenic potentials (VEMPs) have become accepted as a valid method for otolith function assessment. Many studies have identified various vestibular symptoms and laboratory abnormalities in migraineurs. Since migraineurs with no accompanying vestibular symptoms might exhibit subclinical vestibular dysfunction, we investigated vestibular function using ocular and cervical VEMPs in migraine patients. The aim was to study cervical VEMP and occular VEMP in migraineurs with and without vestibular symptoms interictally.

Results
Migraine and VM patients showed significantly longer P13 latency of cVEMP compared to controls. A statistically significant cVEMP interaural P13 latency difference was found in VM compared to healthy controls. Cervical VEMP N23 latency, peak-to-peak amplitude, interaural N23 latency, and amplitude asymmetric ratio did not show any significant difference in migraine and VM patients compared to healthy controls as well as no significant difference across the three groups regarding oVEMP parameters.

Conclusions
Abnormal interictal cVEMP results in migraineurs might indicate subclinical vestibulo-collic pathway dysfunction.
Sleep disorders in attention-deficit hyperactivity disorder and autism spectrum disorder: a pragmatic approach to assessment and management
Authors: Shanahan Paul J. , Isaac Miriam , Blackwell Jane E 
Published: September 2020

SUMMARYSleep is essential for survival and humans spend approximately one-third of their life asleep. Adequate sleep is needed to maintain both physical and psychological health. Routinely getting less than the recommended amount of sleep for your age can have profound negative effects on health, such as increasing the likeliness of psychiatric illness, diabetes, cardiovascular disease and stroke. In children and adults with neurodevelopmental disorders, the prevalence of sleep disorders is significantly higher than in the general population. Given the relationship between sleep and psychiatric disorders, it is essential that psychiatrists have knowledge of the principles of sleep medicine. In this article, we focus on the common sleep disorders found in those with attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) and give an overview of screening, diagnosis and management.
Photoinduced Healing of Mechanically Robust Polymers
Authors: Li Shuxiu , Wu Zehong , Wang Minghao , Wu Si 
Published: September 2020

Abstract
Healing ability extends the lifetime of polymers. Polymeric materials, which are healable under light irradiation, have attracted a lot of attention. Although optically healable polymers have been extensively investigated, mechanically robust yet optically healable polymers are rare. Two types of mechanically robust yet optically healable polymers are introduced in this Highlight Review: (1) healable supramolecular polymers via photothermal effects; (2) azobenzene-containing polymers with photoinduced reversible solid-to-liquid transitions. The design principles of mechanically robust yet optically healable polymers are introduced. The remaining challenges and perspectives are also discussed.
Man's Best Friend? The Effects of Being Rejected by a Pet
Authors: Richman Stephanie B. 
Published: September 2020

Introduction: People can be rejected by friends, strangers, hated outgroups, or computer simulations. The present research examines whether people can be rejected by pets. Methods: Two studies examined whether people can feel rejected by pets and how this affects their mood, fundamental needs, and aggression. Participants in Study 1 were directly rejected by a pet using an adapted version of the video message paradigm, and then reported on their mood, fundamental needs, and aggression. Study 2 directly compared differences in needs when writing about a rejection experience by a pet, a rejection experience by a person, and a control experience. Results: Study 1 confirmed that people can feel rejected by their pets by demonstrating that those who were rejected felt more negatively and less positively and had decreased need satisfaction, however they did not experience any changes in their aggression. Finally, in Study 2, people who were rejected by a pet or by a person experienced decreased need satisfaction as compared to a control experience. Discussion: Ultimately, these studies confirm pets can be perpetrators of rejection and such rejection hurts similarly to if a human perpetrated it. This may add to the growing body of research suggesting that pets do not provide uniformly positive effects on people.
Efficacy and Safety of Ledispavir/Sofosbuvir with or without Ribavirin in patients with Decompensated Liver Cirrhosis and Hepatitis C Infection: a Cohort Study
Authors: Gheorghe Liliana Simona , Preda Carmen , Iliescu Laura , Istratescu Doina , Chifulescu Andreea Elena , Pop Corina Silvia , Trifan Anca , Stanciu Carol , Diculescu Mircea , Voiosu Theodor , Baicus Cristian , Tugui Letitia , Iacob Speranta , Tieranu Cristian , Meianu Corina , Manuc Mircea 
Published: September 2020

Background and Aims: Ledipasvir/Sofosbuvir (LDV/SOF) with or without Ribavirin (RBV) has shown good results in terms of efficacy and safety in clinical trials in advanced liver cirrhosis, but real-life data are still needed in order to confirm this profile. We investigated the efficacy and safety of LDV/SOF in a large Romanian population with liver cirrhosis and genotype 1b hepatitis C virus (HCV).
Methods: We analyzed a multicentric retrospective cohort enrolling 349 patients with decompensated liver cirrhosis due to HCV who received LDV/SOF±RBV 12/24 weeks (301/48). Patients were included between 2017-2018, all with genotype 1b. Main inclusion criteria were liver cirrhosis and detectable HCV RNA. The cases were followed-up monthly during therapy and 12 weeks after the end of therapy.
Results: The cohort included 60% females with a median age of 61, 16% interferon (IFN) pre-treated, 53% with comorbidities, 40/53/7 % with Child Pugh A/B/C, 4% with virus B co-infection and 8% with previously treated hepatocellular carcinoma. Mean initial MELD score was 11.92 (6.82÷ 24.5). Six patients were lost during follow-up. Sustained virologic response (SVR) in intention-to-treat was reported in 85.1%. Predictive factors of SVR in decompensated cirrhosis were female gender (p=0.01), advanced age (p<0.001), lower bilirubin levels (p=0.002) and lower CTP score (p=0.02). In patients with CTP score B or C low bilirubin levels (p=0.003), low INR (p<0.001), increased platelet count (p=0.04), low CTP score (p<0.001), lack of encephalopathy (p=0.02), serum albumin >3.5g/dl (p=0.002) predicted improvement of liver function. Serious adverse events were reported in 16/349 (4.6%), most of them due to severe liver decompensation (9/16).
Conclusions: LDV/SOF±RBV proved to be highly efficient in our difficult to treat population with 85.1% SVR.
Orchestrated Testing of Formula Type to Reduce Length of Stay in Neonatal Abstinence Syndrome
Authors: Kaplan Heather C. , Kuhnell Pierce , Walsh Michele C. , Crowley Moira , McClead Richard , Wexelblatt Scott , Ford Susan , Provost Lloyd P. , Lannon Carole , Macaluso Maurizio ,   OHIO PERINATAL QUALITY COLLABORATIVE
Published: September 2020

BACKGROUND:
Despite the standardization of care, formula feeding varied across sites of the Ohio Perinatal Quality Collaborative (OPQC). We used orchestrated testing (OT) to learn from this variation and improve nonpharmacologic care of infants with neonatal abstinence syndrome (NAS) requiring pharmacologic treatment in Ohio.

METHODS:
To test the impact of formula on length of stay (LOS), treatment failure, and weight loss among infants hospitalized with NAS, we compared caloric content (high versus standard) and lactose content (low versus standard) using a 22 factorial design. During October 2015 to June 2016, OPQC sites joined 1 of 4 OT groups. We used response plots to examine the effect of each factor and control charts to track formula use and LOS. We used the OT results to revise the nonpharmacologic bundle and implemented it during 2017.

RESULTS:
Forty-seven sites caring for 546 NAS infants self-selected into the 4 OT groups. Response plots revealed the benefit of high-calorie formula (HCF) on weight loss, treatment failure, and LOS. The nonpharmacologic treatment bundle was updated to recommend HCF when breastfeeding was not possible. During implementation, HCF use increased, and LOS decreased from 17.1 to 16.4 days across the OPQC.

CONCLUSIONS:
OT revealed that HCF was associated with shorter LOS in OPQC sites. Implementation of a revised nonpharmacologic care bundle was followed by additional LOS improvement in Ohio. Despite some challenges in the implementation of OT, our findings support its usefulness for learning in improvement networks.
Obesidad, inflamación y embarazo, una tríada peligrosa
Authors: Soca Pedro Enrique Miguel , Díaz Gisela Eduarda Feria , Benítez Sonia Noemí González , Montero María de los Ángeles Leyva 
Published: September 2020

Introducción: La obesidad, un estado común durante la etapa pregestacional y el embarazo, representa una condición peligrosa para la salud materno-infantil por sus notables complicaciones obstétricas y perinatales.
Objetivo: Describir los vínculos patogénicos entre obesidad, inflamación y embarazo.
Métodos: Esta revisión bibliográfica se realizó principalmente en PubMed Central, SciELO y ClinicalKey, con los descriptores obesity, inflammation y pregnancy.
Resultados: Entre los efectos desfavorables de la obesidad se encuentran abortos, diabetes gestacional, hipertensión, macrosomia, parto pretérmino, anomalías congénitas y muerte fetal. A largo plazo se asocia también con trastornos metabólicos y enfermedades en las madres y sus descendientes. Estos efectos desfavorables se relacionan con un estado de inflamación crónica de bajo grado que acompaña el exceso de peso corporal. En este proceso inflamatorio juegan un papel importante el tejido adiposo y la placenta con la secreción excesiva de citoquinas proinflamatorias (TNFα, IL-6, IL-1β, proteína 1 quimiotáctica de monocitos, proteína A amiloide sérico) y la reducción de citoquinas antiinflamatorias. Dos mediadores como leptina y adiponectina tienen papeles cruciales.
Conclusiones: Aunque no se conocen bien los mecanismos que vinculan los efectos negativos de la obesidad sobre el embarazo, es probable que la inflamación crónica de bajo grado sea el vínculo principal; por tanto, la tríada obesidad, inflamación y embarazo representa una relación peligrosa para la salud materno-fetal.
DRAMA MUSIKAL UNTUK MENGEMBANGKAN KREATIVITAS DAN ANTUSIASME ANAK BERKEBUTUHAN KHUSUS
Authors: Nazihah Wafiqotin , Anggraini Purwati 
Published: September 2020

Children with special needs are still considered troublesome children for some people, this child has physical and mental limitations and an abnormal mindset like other children, so this makes them marginalized. Whereas the history of human life actually revelas that many Children with special needs have advantages, works of art produced by children have high values, so it needs support and encouragement from the people closest to be able develop their talents. Research on children ia focused on creativity and enthusiasm by using qualitative research methods to describe the overall abilities that Children with special needs can realize with detailed descriptions.The research objective is to describe the potential of children through musical drama, in musical drama not only singing but also collaborating dubbing, dancing, music, and acting as well as being holistic, able to show all the abilities of children in on appearance. The results showed taht musical drama is able to make Children with special needs more sensitive to their environment, because the stimulation of the implementation of musical drama exercises results in changes in body movements and emotions of children while learning musical drama is very influential on creativity and antusiasm anak berkebutuhan khusus.
Stasis-Maintenance-(Un)productive-Presence: Parenting a Disabled Child as Crip Time
Authors: Davidson Adam W. 
Published: September 2020

In what follows, I represent and analyze time as "crip time" in the context of parenting a child with disabilities. That is, I seek to challenge, reimagine, and even upend, the normalized structures that often order our lives in time and our expectations of what makes for a meaningful life in the present, and as a result, a desirable, or even possible future. Using Alison Kafer's Feminist, Queer, Crip as a foundation, in four autoethnographic accounts, recounting a typical day in my life with my 15-year-old son, I consider time as Stasis, Maintenance, (Un)productive, and Presence.
Rethinking Citizenship, Self-Help, and Disability in Local Context: Solidaridad as disability citizenship in Nicaragua
Authors: Meyers Stephen 
Published: September 2020

The concept of citizenship was instrumental to the formation of the disability movement in the West by recasting disability as the denial of equal citizenship of persons with impairments. The disability movement expanded notions of citizenship by not only focusing on nondiscrimination and the protection of civil and political rights, but also the necessity of self-directed, but state-provided, social rights as prerequisite for substantive equality. With the passage of the Convention on the Rights of Persons with Disabilities, Western approaches to disability citizenship as state protected rights have globalized. Critical disability scholars are increasingly arguing that Western theories of disability, citizenship, and rights are inappropriate in local contexts in the Global South where weak welfare states are the reality. In such cases, self-help and mutual support are more determinative in the lives of disabled persons than formal rights. I extend these arguments by analyzing three grassroots disability associations in Nicaragua that assist their members achieve citizenship through self-help, service and solidaridad with the community.
Changes in procoagulant activity during pregnancy in women with drug addiction
Authors: Л. В. Суслікова  , І. В. Малишева  , В. В. Камінський  , К. В. Чайка  , А. В. Камінський  , А. В. Сербенюк  
Published: September 2020

Objective: to study hemostatic features of procoagulant link in pregnant women with drug addiction.Materials and methods. 156 pregnant women were examined: 96 women with drug addiction (main group) and 60 pregnant women in control group. All patients tests for hemostatic system by avaluation of total fibrinogen, prothrombin by Quick, activated partial thromboplastin time, and the mother-placenta-fetus system state. Ultrasound (Doppler ultrasound) was performed to estimate of fetoplacental complex.Results. Shifts of coagulation system to the hypercoagulation state in women with drug addiction were noted, it was manifested by an increase in fibrinogen, prothrombin by Quick and a decrease in activated partial thromboplastin time. Significant difference in these indicators was revealed in drug-dependent pregnant women compared with the control group (p <0.05). There were also changes in the mother-placenta-fetus system with doppler ultrasound, which manifested by a clinically significant deterioration in blood flow in the uterine arteries (p <0.05).Conclusions. The course of pregnancy in women with drug addiction is characterized by the development of a hypercoagulable state. It causes thrombosis, diapedetic hemorrhage. This condition without correction subsequently leads to bleeding, as a result of intrauterine growth retardation, antenatal fetus death in the worst case.Pregnant with drug addiction in the third trimester characterized hypercoagulation state, that is as indicated by an increase in fibrinogen, prothrombin by Quick and shortening of the activated partial thromboplastin time in comparison with pregnant women in the control group. A high proportion of gestational and perinatal complications was revealed in women of the main group (placental structural changes, hemodynamic disturbances of the second and third stages in the mother-placenta-fetus system and fetal growth retardation).
The Correlation Between Lipid Profile and Xanthelasma
Authors: Kampar Puridelko 
Published: September 2020

Background: Xanthelasma is an abnormal lipid deposition on palpebrae, which is observable as yellowish plaque or nodules. Its incidence is 0.56–1.5% with onset of 15–73 years old and mostly occurs in the fourth and fifth decade. Few reports of xanthelasma did not cover the correlation between lipid profile and xanthelasma in Indonesia. Purpose: To find a correlation between lipid profile with xanthelasma in Dr. M. Djamil Hospital, Padang. Methods: This was an analytic cross-sectional study with consecutive sampling. There were 36 participants (18 xanthelasma and 18 control). Result: The highest age group was >36 - ≤45 years old (38.89%). More cases were observed in female (66.67%). Body mass index examination of xanthelasma revealed that most were overweight (55.56%). Grade I xanthelasma was the most common (72.22%). The cholesterol serum level of xanthelasma patients was higher than the subject controls (224.61±29.77 mg/dl versus­ 169.39±35.84 mg/dl) (p<0,05). The High Density Lipoprotein (HDL) serum level of xanthelasma patients was lower than controls (46.44±14.19 mg/dl versus 51.78±15.9 mg/dl) (p>0,05). The Low Density Lipoprotein (LDL) serum level of xanthelasma patients was higher than control (139.39±29.73 mg/dl versus 106.50±35.43 mg/dl) (p<0,05). Triglyceride serum level of xanthelasma patients was higher than the controls (167.83±87.26 mg/dl versus 121.61±54.52 mg/dl) (p>0,05). Conclusion: There was a correlation between higher cholesterol and LDL serum level with xanthelasma. No correlation between lower HDL and a higher triglyceride serum level with xanthelasma.