bluuebunny/crossref_metadata_2025_split huggingface dataset:
Building attention and edge message passing neural networks for bioactivity and physical–chemical property prediction
Authors: Withnall M. , Lindelöf E. , Engkvist O. , Chen H. 
Published: January 2020

AbstractNeural Message Passing for graphs is a promising and relatively recent approach for applying Machine Learning to networked data. As molecules can be described intrinsically as a molecular graph, it makes sense to apply these techniques to improve molecular property prediction in the field of cheminformatics. We introduce Attention and Edge Memory schemes to the existing message passing neural network framework, and benchmark our approaches against eight different physical–chemical and bioactivity datasets from the literature. We remove the need to introduce a priori knowledge of the task and chemical descriptor calculation by using only fundamental graph-derived properties. Our results consistently perform on-par with other state-of-the-art machine learning approaches, and set a new standard on sparse multi-task virtual screening targets. We also investigate model performance as a function of dataset preprocessing, and make some suggestions regarding hyperparameter selection.
Co-composting of chicken manure with organic wastes: characterization of gases emissions and compost quality
Authors: Hwang Hyun Young , Kim Seong Heon , Kim Myung Sook , Park Seong Jin , Lee Chang Hoon 
Published: January 2020

AbstractCo-composting of organic wastes is globally recognized to be effective method to dispose two or more wastes at once and minimize drawbacks of composting such as gases emissions and nutrient reduction. In this study, pilot-scale experiments were conducted to characterize the co-composting process of chicken manure with cow manure (CC), swine manure (CS), plant residues plus mushroom media (CRM), on emissions of greenhouse gas, and ammonia, compost quality, maturity and their correlations. The results showed that cumulative flux of carbon dioxide (CO2), methane (CH4), nitrous oxide (N2O) and ammonia (NH3) widely ranged like 38,211–50,830, 172–417, 98–142 and 118–927 g kg dm−1 day−1 respectively. It indicated the importance of selection for co-composting material. The NH3 emission was significantly increased by 4.3–7.9 times in CS and CRM, compared to OC and CC. Both of CS and CRM also showed longer thermophilic phase and later maturation were also observed in both treatments. Temperature was positively correlated with gases (P < 0.001) except CH4, and nitrogen content, C/N ratio and nitrate nitrogen significantly affected emission of carbon and nitrogen (P < 0.001). In conclusion, for chicken manure composting, sole chicken manure or combination with cow manure could be suitable composting method to improve compost quality and minimize gases losses.
A sustainable process for biodiesel production using Zn/Mg oxidic species as active, selective and reusable heterogeneous catalysts
Authors: Navas Marisa B. , Ruggera José F. , Lick Ileana D. , Casella Mónica L. 
Published: January 2020

AbstractThis paper describes the preparation and characterization of MgO and ZnO-based catalysts, pure and mixed in different proportions, supported on γ-Al2O3. Their catalytic performance was studied in the transesterification of soybean oil and castor oil with methanol and butanol, attempting to produce biodiesel. XRD (X-ray diffraction), SEM–EDS (scanning electron microscopy–energy dispersive X-ray spectroscopy), CO2-adsorption and N2-adsorption allowed characterizing the prepared catalysts. The characterization results were in all cases consistent with mesoporous solids with high specific surface area. All the catalysts exhibited good results, especially in the transesterification of castor oil using butanol. For this reaction, the reuse was tested, maintaining high FABE (fatty acid butyl esters) yields after four cycles. This good performance can be attributed to the basic properties of the Mg species, and simultaneously, to the amphoteric properties of ZnO, which allow both triglycerides and free fatty acids to be converted into esters. Using these catalysts, it is possible to obtain second-generation biodiesel, employing castor oil, a raw material that does not compete with the food industry. In addition, butanol can be produced from renewable biomass.
The assessment of quantitative risk to road users from debris flow
Authors: Winter M. G. , Wong J. C. F. 
Published: January 2020

Abstract
Background
A methodology for the quantitative risk assessment (QRA) of the impact of debris flow in a road environment has been developed and applied to two sites that are typically subject to high frequency-low magnitude and low frequency-high magnitude events. The methodology considers the probability of an event of a typical size, and the conditional probabilities of a vehicle being affected, given an event, and of damage (fatality) occurring given that the vehicle is affected. Scenarios covering a vehicle being hit by a debris flow and of a vehicle hitting a debris flow are considered. The computed Personal Individual Risk (PIR) is used to calculate worst case fatality probabilities for commuters and logistics truck drivers. The overall risk to society is expressed both by the annual probability of fatality amongst all road users, the Potential Loss of Life (PLL), and using the F-N diagram and is used to demonstrate the effect of a programme of management and mitigation works on the societal risk at one of the sites. The authors believe that this is the first full, formal quantitative risk assessment for debris flow risk to road users.

Results
The PIR for a single trip through the sites ranges between 1.147E-10 for the low frequency-high magnitude site and 1.583E-09 for the high frequency-low magnitude site. These figures increase to 1.248E-07 and 1.922E-06, respectively, when more frequent travellers are considered. The PLL for the two sites ranges between 2.616E-04 for the low frequency-high magnitude site and 4.083E-03 for the high frequency-low magnitude site. The F-N diagrams illustrate the Broadly Acceptable level of risk at the low frequency-high magnitude site and the partially Unacceptable level of risk at the high frequency-low magnitude site. The risk at the high frequency-low magnitude site is reduced to ALARP levels when management and mitigation measures extant as of October 2014 are considered.

Conclusions
The QRA proves an effective technique for understanding, comparing and articulating the differences in levels of risk and the temporal changes in risk at a given site as a result of landslide risk reduction activities.
Partial portal vein arterialization during living-donor liver transplantation: a case report
Authors: Maruya Yasuhiro , Hidaka Masaaki , Pecquenard Florian , Baubekov Alzhan , Nunoshita Yuki , Ono Shinichiro , Adachi Tomohiko , Takatsuki Mitsuhisa , Tanaka Katsumi , Ito Shinichiro , Kanetaka Kengo , Eguchi Susumu 
Published: January 2020

Abstract
Background
Hepatic artery thrombosis can lead to graft loss associated with severe hepatic infarction or bile duct ischemia. When anatomical hepatic artery reconstruction is impossible in liver transplantation or hepato-pancreatic biliary surgery, portal vein arterialization (PVA) is proposed as a salvage technique. Herein, we report our experience with a case that showed favorable clinical outcomes after partial PVA during living-donor liver transplantation (LDLT) because of difficulties in arterial reconstruction.

Case presentation
A 62-year-old woman with non-B, non-C liver cirrhosis complicated with hepatocellular carcinoma was being prepared for LDLT using an extended left lobe graft. The graft presented with two arteries (left hepatic artery, 2 mm; middle hepatic artery, 2 mm). The first anastomosis was performed using the recipient hepatic artery stumps, but no flow was detected on Doppler control because of thrombus formation. The next attempt was executed using the middle colic artery with a radial artery jump graft and the right gastroepiploic artery, but it led to the same result. Thus, the graft oxygen support by the standard arterial procurement was abandoned, and a shunt was created between the ileocecal artery and the vein to obtain PVA. Arteriography of the superior mesenteric artery showed that the shunt was relatively patent, and the portal vein was apparent. No biliary complication or liver abscess occurred postoperatively, and the patient presented with good liver function and no complications related to portal vein hypertension, nor liver fibrosis 18 months after the LDLT.

Conclusion
Partial PVA with a shunt created between the ileocecal artery and the vein is useful when arterial reconstruction is difficult during LDLT for preventing graft loss caused by severe hepatic infarction or bile duct ischemia.
Evaluation of fluorinated hydroxyapatite nanoparticles as an antibacterial material for catheter coating
Authors: Gyotoku Hiroki , Azuma Yoshinano , Furuzono Tsutomu 
Published: January 2020

AbstractBackgroundCatheter-related infection of peritoneal dialysis (PD) is one of the serious factors of peritonitis. However, an antibacterial PD catheter has not been commercially available in Japan yet. From an infection control viewpoint, it is necessary to develop an antibacterial coating material for catheters with a long-term effectiveness.MethodsFluorinated hydroxyapatite (F-HAp) nanoparticles were prepared by a wet chemical process. F-HAps with different F substitution contents were prepared by adjusting the feed ratio of F ions versus sites of OH groups in HAp structures. The characterization and evaluation of F-HAps were conducted using several analytical equipment and an antibacterial powder assay.ResultsThe F-HAp nanoparticles possessed highly crystalline and dispersibility. The F-HAps were named as F(30)-HAp, F(50)-HAp, and F(100)-HAp and were 24, 52, and 84% of the actual F substitution content, respectively. The nanomaterials showed acidic resistance, i.e., chemical stability, compared to normal HAp. In an antibacterial assay of F(100)-HAp with 50 mg in 0.2 mL of NaCl aqueous solution, four types of causative bacteria of catheter-related infections,Pseudomonas aeruginosa,Staphylococcus aureus,Enterobacter aerogenes, andKlebsiella pneumoniaewere used. The antibacterial activities of F(100)-HAp showed 50–60% against the microorganisms. F ions were gradually released and finally plateaued at 24 weeks.ConclusionsThe retention possibility of the antibacterial effect of F(100)-HAp potentially lasted for 24 weeks based on the F ions release behavior. It is expected that the antibacterial performance can be improved by the precise control of material engineering technology, although the duration of the effect has not yet been satisfactory for a PD catheter.
Round robin comparison study on the form measurement of optical freeform surfaces
Authors: Fortmeier Ines , Schachtschneider Reyko , Ledl Vit , Matousek Ondrej , Siepmann Jens , Harsch Antonia , Beisswanger Rolf , Bitou Youichi , Kondo Yohan , Schulz Michael , Elster Clemens 
Published: January 2020

AbstractA round robin comparison of freeform form measurements was carried out by the project partners and stakeholders of a European metrology research project. Altogether six measuring instruments were considered: five different (pointwise and areal) optical devices and one tactile device. Three optical freeform surfaces were used for the comparison measurements, where two specimens were measured by five instruments and one specimen by four instruments. In this paper, the evaluation methods and results of this round robin are presented for the three freeform surfaces made from a temperature-stable material, Super Invar®. The freeforms had diameters of 40 mm, 50 mm and 100 mm and best-fit radii of 39.75 mm (convex), 40.9 mm (convex) and 423.5 mm (concave). For comparison, the bilateral pointwise differences between the available measurements were calculated. The root-mean-square values of these differences ranged from 15 nm to 110 nm (neglecting spherical contributions) and provided an insight into the status of typical freeform measurement capabilities for optical surfaces.
Transsplenic portal vein recanalization and direct intrahepatic portosystemic shunt placement to optimize liver transplantation
Authors: Ahmed Osman , Salaskar Abhijit L. , Zangan Steven , Pillai Anjana , Baker Talia 
Published: January 2020

Abstract
Background
Percutaneous trans-splenic portal vein recanalization (PVR) has been reported for facilitation of transjugular intrahepatic portosystemic shunts (TIPS), however has not been applied to patients undergoing direct intrahepatic portosystemic shunt (DIPS). We report the utilization of trans-splenic-PVR with DIPS creation in a patient with chronic portal and hepatic vein occlusions undergoing liver transplantation evaluation.

Case presentation
A 48-year-old male with decompensated alcoholic cirrhosis complicated by refractory ascites, hepatic encephalopathy, and variceal bleeding underwent CT that demonstrated chronic occlusion of the hepatic veins (HV), extrahepatic portal vein (PV), and superior mesenteric vein (SMV). Due to failed attempts at TIPS at outside institutions, interventional radiology was consulted for portal vein recanalization (PVR) with TIPS to treat the portal hypertension and ascites and also facilitate an end-to-end PV anastomosis at transplantation. After an initial hepatic venogram confirmed chronic HV occlusion, a DIPS with trans-splenic PVR was planned. The splenic vein was accessed under sonographic guidance using a micropuncture set and subsequently upsized to a 6 French sheath over a stiff guidewire. A splenic venogram via this access confirmed occlusion of the PV with drainage of the splenic vein (SV) through gastric varices. The thrombosed PV was then recanalized and angioplastied to restore PV flow via the transsplenic approach. A transjugular liver access kit with a modified 21-gauge needle was advanced into the IVC through the internal jugular vein (IJV) sheath and directed towards the target snare in PV. The needle was used to subsequently puncture the PV through the caudate lobe and facilitate placement of a wire into the SV. The initial portosystemic gradient (PSG) was 20 mmHg. The IJV sheath was advanced through the hepatic parenchymal tract into the main-PV and a stent-graft was placed across the main PV and into the IVC. A portal venogram demonstrated brisk blood flow through the DIPS, resolution of varices and a PSG of 8 mmHg. One month after the procedure, the patient had a significant reduction in ascites and MELD-NA score. Patient is currently listed and awaiting transplantation.

Conclusions
In the setting of chronically occluded portal and hepatic veins, trans-splenic PVR DIPS may serve as an effective bridge to liver transplantation by facilitating an end to end portal vein anastomosis.
Optimization of biogas supply networks considering multiple objectives and auction trading prices of electricity
Authors: Egieya Jafaru Musa , Čuček Lidija , Zirngast Klavdija , Isafiade Adeniyi Jide , Kravanja Zdravko 
Published: January 2020

AbstractThis contribution presents an hourly-based optimization of a biogas supply network to generate electricity, heat and organic fertilizer while considering multiple objectives and auction trading prices of electricity. The optimization model is formulated as a mixed-integer linear programming (MILP) utilizing a four-layer biogas supply chain. The model accounts for biogas plants based on two capacity levels of methane to produce on average 1 ± 0.1 MW and 5 ± 0.2 MW electricity. Three objectives are put forward: i) maximization of economic profit, ii) maximization of economic profit while considering cost/benefits from greenhouse gas (GHG) emissions (economic+GHG profit) and iii) maximization of sustainability profit. The results show that the economic profit accrued on hourly-based auction trading prices is negative (loss), hence, four additional scenarios are put forward: i) a scenario whereby carbon prices are steadily increased to the prevalent eco-costs/eco-benefits of global warming; ii) a scenario whereby all the electricity auction trading prices are multiplied by certain factors to find the profitability breakeven factor, iii) a scenario whereby shorter time periods are applied, and investment cost of biogas storage is reduced showing a relationship between cost, volume of biogas stored and the variations in electricity production and (iv) a scenario whereby the capacity of the biogas plant is varied from 1 MW and 5 MW as it affects economics of the process. The models are applied to an illustrative case study of agricultural biogas plants in Slovenia where a maximum of three biogas plants could be selected. The results hence present the effects of the simultaneous relationship of economic profit, economic+GHG profit and sustainability profit on the supply and its benefit to decision-making.
Case report of gastric teratoma masquerading as neonatal intestinal obstruction
Authors: Chatterjee Rajib , Singh Abhijit , Gharpure Vivek 
Published: January 2020

Abstract
Background
Teratomas are rare in neonates. They are embryonic neoplasms containing elements from all the three germ layers. Commonly, they arise in the ovary and testis. Rarely do they arise from the gastrointestinal tract, as in our case. Intestinal obstruction in neonates is usually due to congenital obstructive malformation such as atresia and/or stenosis of the gastrointestinal tract with or without sepsis.

Case presentation
An outborn 5-day neonate, generally well before admission presented with non-bilious vomiting, abdominal distension and a palpable mass extending from the right to left flank across the centre. Bilious aspirates/vomiting usually indicates obstruction distal to the ampulla of Vater. Clear aspirates indicate obstruction proximal to the ampulla which usually present by second day of life.
Possibility of a mass lesion such as a “teratoma” causing gastrointestinal obstruction needs a high index of suspicion. Imaging studies of plain X-ray chest with abdomen enhanced our clinical suspicion which was promptly followed by ultrasonography of the abdomen and thereafter computerized tomography of the abdomen which provided corroborative evidence. Laparotomy on the seventh day of life confirmed the clinical suspicion and imaging evidence of an exogastric mass arising from the postero-inferior wall of the stomach along its greater curvature. Histopathology revealed a mature teratoma.

Conclusion
A high index of clinical suspicion by the paediatrician/neonatologist attending a neonate with abdominal distension suggestive of gastrointestinal obstruction, immediate cardiopulmonary, hemodynamic and circulatory stabilization, followed by prompt and appropriate imaging studies with timely surgical consultation holds the key to quality outcome.
A simplified laparoscopic-assisted gastrostomy technique: a single center experience
Authors: Sheir Hesham M. , Wafa Tamer A. , Elshafey Abdelrahman , Elzohiri Mohamed 
Published: January 2020

AbstractBackgroundAlthough percutaneous endoscopic gastrostomy (PEG) is considered simple and effective, major complications have been reported because of the partly blind placement technique. Laparoscopic gastrostomy was described to overcome most of the problems and the contraindications of PEG. Various modifications have been reported to anchor the stomach to the abdominal wall.This study aims at highlighting a single center experience using a simplified technique for gastrostomy and evaluates its outcome.ResultsThe age of the patients ranged from 7 days to 3 years (mean 11.75 ± 12 months in group A and 16 ± 3 months in group B). The mean body weight at time of gastrostomy was 6.5 ± 4.6 kg in group A and 7.5 ± 2 in group B. The mean operative time was 24.8 ± 4 min in group A and 25 ± 1.6 in group B, ranging from 18 to 31 min. The incidence of gastrostomy-related complications was 20% (three cases) in group A versus 12.5% (one case) among patients included in group B. Yet, this difference was statistically insignificant (p= 0.651). No major complications were reported apart from persistent gastrocutaneous fistula in one out of eight cases followed after removal of the gastrostomy (12.5%). There is no significant difference in the outcome either in neonates or in patients less than 5 kg.ConclusionsThe described simple technique of laparoscopic-assisted gastrostomy is easy, effective, and with a very low incidence of complications. It is also equally safe in neonates and children less than 5 kg.
Electromagnetic characterization of epithermal gold deposits: A case study from the Tuoniuhe gold deposit, Northeast China
Authors: Xu Shan , Xu Fengming , Hu Xiangyun , Zhu Qun , Zhao Yuandong , Liu Shuang 
Published: January 2020

A high-resolution electromagnetic study has helped to define the mineralization and alteration system of the Cretaceous volcano-sedimentary hosted epithermal gold (Au) deposit in Tuoniuhe, northeast China. Audio-magnetotelluric (AMT) array data were acquired to map the regional resistivity structure of the Mesozoic volcanic field, whereas an AMT profile and a ground magnetic survey line with denser site spacing were deployed across the deposit to image the alteration and mineralization system. The electrical resistivity model from 2D inversion of the AMT profile data reveals a low-resistivity (approximately [Formula: see text]) cover from the surface to a depth of 0.1 km, which is likely caused by clay and sulfide minerals in the subaerial alteration zone. The magnetic survey and a geologic borehole log assisted in outlining a zone of tonalite and andesite with silicification in the depth interval of 0.1–0.3 km, featuring high resistivity ([Formula: see text]) and high magnetization ([Formula: see text]). This zone is a potential gold target bounded by two channels of moderate resistivity (approximately [Formula: see text]) to its northwest and southeast. The two channels possibly coincide with breccia pipes with fractured stockworks and high permeability to allow gold-bearing fluids to move toward the surface. The 2D and 3D resistivity models reveal regions of low resistivity ([Formula: see text]) at the depth range of 0.5–1.0 km beneath the Cretaceous calderas and the deposit, which might be related to magmatic cryptoexplosion breccia. In the 2D resistivity model, this magmatic cryptoexplosion breccia zone connects to the subaerial alteration zone through the two breccia pipes, indicative of a circulation system of gold-bearing fluids. Given the coincidence of Cretaceous volcanism and the age of mineralization, the Cretaceous magma is inferred to have supplied heat that drove the convective hydrothermal activity and also was a source of magmatic fluids that led to the development of the Tuoniuhe epithermal gold deposit.