bluuebunny/crossref_metadata_2025_split huggingface dataset:
Summary of the International Patient Safety Conference, June 28—29, 2019, Kathmandu, Nepal
Authors: Bajracharya Deepak C. , Karki Kshitij , Lama Chhiring Yangjen , Joshi Rajesh Dhoj , Rai Shankar Man , Jayaram Sudhakar , Tomer Amit , Zervos John , Khan Mohammad Imran , Sapkota Arjun , Upadhyaya Madan Kumar , Kilgore Paul E. 
Published: November 2019

AbstractGlobally, medical errors are associated with an estimated $42 billion in costs to healthcare systems. A variety of errors in the delivery of healthcare have been identified by the World Health Organization and it is believed that about 50% of all errors are preventable. Initiatives to improve patient safety are now garnering increased attention across a range of countries in all regions of the world. From June 28--29, 2019, the first International Patient Safety Conference (IPSC) was held in Kathmandu, Nepal and attended by over 200 healthcare professionals as well as hospital, government, and non-governmental organization leaders. During the conference, presentations describing the experience with errors in healthcare and solutions to minimize future occurrence of adverse events were presented. Examples of systems implemented to prevent future errors in patient care were also described. A key outcome of this conference was the initiation of conversations and communication among important stakeholders for patient safety. In addition, attendees and dignitaries in attendance all reaffirmed their commitment to furthering actions in hospitals and other healthcare facilities that focus on reducing the risk of harm to patients who receive care in the Nepali healthcare system. This conference provides an important springboard for the development of patient-centered strategies to improve patient safety across a range of patient care environments in public and private sector healthcare institutions.
Evaluation of an alpha-cypermethrin + PBO mixture long-lasting insecticidal net VEERALIN® LN against pyrethroid resistant Anopheles gambiae s.s.: an experimental hut trial in M’bé, central Côte d’Ivoire
Authors: Oumbouke Welbeck A. , Rowland Mark , Koffi Alphonsine A. , Alou Ludovic P. A. , Camara Soromane , N’Guessan Raphael 
Published: November 2019

Abstract
Background
Long-lasting insecticidal nets (LLINs) are the primary method of malaria prevention. However, the widespread resistance to pyrethroids among major malaria vector species represents a significant threat to the continued efficacy of pyrethroid LLIN. Piperonyl butoxide (PBO) is a synergist that inhibits the activity of metabolic enzymes of the cytochrome P450 family known to detoxify insecticides including pyrethroids. Synergist LLIN incorporating PBO and a pyrethroid may provide improved control compared to pyrethroid-only LLIN.

Methods
The efficacy of VEERALIN® LN (VKA polymers Pvt Ltd, India), an alpha-cypermethrin PBO synergist net was evaluated in experimental huts in M’bé, central Côte d’Ivoire against wild pyrethroid resistant Anopheles gambiae s.s. Comparison was made with a standard alpha-cypermethrin-treated net (MAGNet® LN, VKA polymers Pvt Ltd, India). Nets were tested unwashed and after 20 standardized washes.

Results
VEERALIN® LN demonstrated improved efficacy compared to MAGNet® LN against wild free-flying pyrethroid-resistant An. gambiae s.s. Before washing, VEERALIN® LN produced mortality of An. gambiae s.s. (51%) significantly higher than the standard pyrethroid-only net (29%) (P < 0.0001). Although there was a significant reduction in mortality with both LLINs after 20 washes, VEERALIN® LN remained superior in efficacy to MAGNet® LN (38 vs 17%) (P < 0.0001). Blood-feeding was significantly inhibited with both types of insecticide-treated nets relative to the untreated control net (P < 0.0001). Unwashed VEERALIN® LN induced significantly higher blood-feeding inhibition of An. gambiae s.s. (62.6%) compared to MAGNet® LN (35.4%) (P < 0.001). The difference persisted after washing, as there was no indication that either LLIN lost protection against biting or blood-feeding. The level of personal protection derived from the use of VEERALIN® LN was high (87%) compared to MAGNet® LN (66–69%) whether unwashed or washed. The AI content of VEERALIN® LN after 20 washes decreased from 6.75 to 6.03 g/kg for alpha-cypermethrin and from 2.95 to 2.64 g/kg for PBO, corresponding to an overall retention of 89% for each compound.

Conclusions
The addition of the synergist PBO to pyrethroid net greatly improved protection and control of pyrethroid-resistant An. gambiae s.s. The pyrethroid-PBO VEERALIN® LN has the potential to reduce transmission in areas compromised by pyrethroid resistance.
Some new fractional integral inequalities for exponentially m-convex functions via extended generalized Mittag-Leffler function
Authors: Rashid Saima , Safdar Farhat , Akdemir Ahmet Ocak , Noor Muhammad Aslam , Noor Khalida Inayat 
Published: November 2019

AbstractIn the article, we establish some new general fractional integral inequalities for exponentially m-convex functions involving an extended Mittag-Leffler function, provide several kinds of fractional integral operator inequalities and give certain special cases for our obtained results.
Social network analysis in Telecom data
Authors: Al-Molhem Nour Raeef , Rahal Yasser , Dakkak Mustapha 
Published: November 2019

AbstractMany systems can be represented as networks or graph collections of nodes joined by edges. The social structures in these networks can be investigated using graph theory through a process called social network analysis (SNA). In this paper, networks and SNA concepts were applied using Telecom data such as call detail records (CDRs) and customers data to model our social network and to construct a weighed graph in which each relation carries a different weight, representing how close two subscribers are to each other. In addition, SNA is used to explore the Telecom network and calculate the centrality measures, which help determine the node importance in the network. Depending on centrality measures as well as influence capability of node measure, the influencers in network were detected and targeted by marketing campaigns resulting in 30% raise in growth rate of mobile traffic compared with traditional ways. Finding Multi-SIM subscribers within the same operator or across different operators presents another important concern to Telecom companies because it allows to improve campaigns and churn prediction models. Social network similarity measures and social behavioral measures between nodes were calculated in the Telecom network to detect these Multi-SIM subscribes and 85% accuracy result was achieved for subscribes from different operators and 92% for subscribes from the same operator. The paper is based on a real dataset of 3 months CDRs and customer data provided by a local Telecom operator. This dataset is used to build a network with more than 16 million nodes and more than 300 million edges on a big data platform.
Real-time high-resolution video stabilization using high-frame-rate jitter sensing
Authors: Raut Sushil , Shimasaki Kohei , Singh Sanjay , Takaki Takeshi , Ishii Idaku 
Published: November 2019

AbstractIn this study, the novel approach of real-time video stabilization system using a high-frame-rate (HFR) jitter sensing device is demonstrated to realize the computationally efficient technique of digital video stabilization for high-resolution image sequences. This system consists of a high-speed camera to extract and track feature points in gray-level $$512\times 496$$512×496 image sequences at 1000 fps and a high-resolution CMOS camera to capture $$2048\times 2048$$2048×2048 image sequences considering their hybridization to achieve real-time stabilization. The high-speed camera functions as a real-time HFR jitter sensing device to measure an apparent jitter movement of the system by considering two ways of computational acceleration; (1) feature point extraction with a parallel processing circuit module of the Harris corner detection and (2) corresponding hundreds of feature points at the current frame to those in the neighbor ranges at the previous frame on the assumption of small frame-to-frame displacement in high-speed vision. The proposed hybrid-camera system can digitally stabilize the $$2048\times 2048$$2048×2048 images captured with the high-resolution CMOS camera by compensating the sensed jitter-displacement in real time for displaying to human eyes on a computer display. The experiments were conducted to demonstrate the effectiveness of hybrid-camera-based digital video stabilization such as (a) verification when the hybrid-camera system in the pan direction in front of a checkered pattern, (b) stabilization in video shooting a photographic pattern when the system moved with a mixed-displacement motion of jitter and constant low-velocity in the pan direction, and (c) stabilization in video shooting a real-world outdoor scene when an operator holding hand-held hybrid-camera module while walking on the stairs.
Growth kinetics and pathogenicity of Photorhabdus luminescens subsp. akhurstii SL0708
Authors: Orozco-Hidalgo María Teresa , Quevedo-Hidalgo Balkys , Sáenz-Aponte A. 
Published: November 2019

AbstractPhotorhabdus luminescens subsp. akhurstii SL0708 (Enterobacteriaceae) is a symbiont of the entomopathogenic nematode (EPN), Heterorhabditis indica SL0708 (Nematoda: Rhabditida), used for insect pest biological control. In the present study, P. luminescens subsp. akhurstii SL0708 growth kinetic was evaluated considering growth and metabolic phases (phase I, intermediate phase, phase II), as well as pathogenicity. The study can be useful in determining bacterium feeding times in H. indica SL0708 production in liquid culture media. The logarithmic phase of the growth of bacterium was from 0 to 24 h, with a specific growth velocity of 0.21 h−1; during this phase, bacterium at metabolic phase I was detected. Maximum bioluminescence was registered at 24 h (3.437 luminescence AU). Finally, it was evidenced that the bacterial metabolic phase had an effect on the greater wax moth, Galleria mellonella L., larvae mortality rate. Moreover, biochemical tests were the same for all P. luminescens subsp. akhurstii SL0708 sampling times. This research is particularly relevant, since no reports are available on this bacterium isolate in Colombia. In the future, this will allow massive H. indica SL0708 production, because when pre-incubated with its symbiont, it provides essential nutrients for the EPNs development and reproduction.
Next-generation fluorescent nucleic acids probes for microscopic analysis of intracellular nucleic acids
Authors: Okamoto Akimitsu 
Published: November 2019

AbstractFluorescence imaging of nucleic acids is a very important technique necessary to understand gene expression and the resulting changes in cell function. This mini-review focuses on sequence-specific fluorescence imaging of intracellular RNA and methylated DNA using fluorescent nucleic acid probes. A couple of functional fluorescent nucleic acid probes developed by our laboratory are introduced and the examples of their application to fluorescence imaging of intracellular nucleic acids are described.
Supratubal recess and sinus tympani: CT analysis of middle ear hidden areas
Authors: El-Anwar Mohammad Waheed , Eldib Diaa Bakry , Elmalt Ashraf , Khazbak Alaa Omar 
Published: November 2019

Abstract
Background
High-resolution computed tomography (HRCT) magnifies the role of preoperative imaging for detailed middle ear anatomy particularly its hidden area. The purpose of the current study was to assess the sinus tympani (ST) and supratubal recess (STR) by HRCT, to create CT classification of the STR depth, and to study the relationship between ST types and the new STR grades.

Results
In HRCT of non-pathological temporal bones of 100 subjects (200 ears), measurements of the STR and ST were calculated, registered, and analyzed. The depth of the STR was classified into grade 1 with depth less than 3 mm, grade 2 with depth ranged between 3 and 5 mm, and grade 3 with depth more than 5 mm. The mean STR length, width, and height were 4.17 ± 0.86, 3.55 ± 0.65, and 3.64 ± 0.7 mm, respectively, while the ST mean length and width of were 2.52 ± 0.5 and 1.82 ± 0.78 mm, respectively, without significant differences between either sexes or sided. The ST types were found to be type A in 56 ears (28%), type B in 142 ears (71%), and type C in 2 ears (1%). The STR grading was grade 1 in 12 ears (6%), grade 2 in 160 ears (80%), and grade 3 in 28 ears (14%) without significant relationship between ST types and STR grading (P = 0.3).

Conclusion
The current study provided reliable and applicable methods of CT assessment of STR and ST that can help to predict the degree of surgical visibility of the ST and STR during ear surgery.
Dynamic Pituitary–Adrenal Interactions in the Critically Ill after Cardiac Surgery
Authors: Gibbison Ben , Keenan Daniel M , Roelfsema Ferdinand , Evans Jon , Phillips Kirsty , Rogers Chris A , Angelini Gianni D , Lightman Stafford L 
Published: November 2019

Abstract

Context
Patients with critical illness are thought to be at risk of adrenal insufficiency. There are no models of dynamic hypothalamic–pituitary–adrenal (HPA) axis function in this group of patients and thus current methods of diagnosis are based on aggregated, static models.

Objective
To characterize the secretory dynamics of the HPA axis in the critically ill (CI) after cardiac surgery.

Design
Mathematical modeling of cohorts.

Setting
Cardiac critical care unit.

Patients
20 male patients CI at least 48 hours after cardiac surgery and 19 healthy (H) male volunteers.

Interventions
None.

Main Outcome Measures
Measures of hormone secretory dynamics were generated from serum adrenocorticotrophic hormone (ACTH) sampled every hour and total cortisol every 10 min for 24 h.

Results
All CI patients had pulsatile ACTH and cortisol profiles. CI patients had similar ACTH secretion (1036.4 [737.6] pg/mL/24 h) compared to the H volunteers (1502.3 [1152.2] pg/mL/24 h; P = .20), but increased cortisol secretion (CI: 14 447.0 [5709.3] vs H: 5915.5 [1686.7)] nmol/L/24 h; P &lt; .0001). This increase in cortisol was due to nonpulsatile (CI: 9253.4 [3348.8] vs H: 960 [589.0] nmol/L/24 h, P &lt; .0001), rather than pulsatile cortisol secretion (CI: 5193.1 [3018.5] vs H: 4955.1 [1753.6] nmol/L/24 h; P = .43). Seven (35%) of the 20 CI patients had cortisol pulse nadirs below the current international guideline threshold for critical illness-related corticosteroid insufficiency, but an overall secretion that would not be considered deficient.

Conclusions
This study supports the premise that current tests of HPA axis function are unhelpful in the diagnosis of adrenal insufficiency in the CI. The reduced ACTH and increase in nonpulsatile cortisol secretion imply that the secretion of cortisol is driven by factors outside the HPA axis in critical illness.
Isolated 17,20-Lyase Deficiency in a CYB5A Mutated Female With Normal Sexual Development and Fertility
Authors: Leung Mei Tik , Cheung Hoi Ning , Iu Yan Ping , Choi Cheung Hei , Tiu Sau Cheung , Shek Chi Chung 
Published: November 2019

Abstract
Isolated 17,20-lyase deficiency may be caused by mutations in the CYP17A1 (coding for cytochrome P450c17), POR (coding for cytochrome P450 oxidoreductase) and CYB5A (coding for microsomal cytochrome b5) genes. Of these, mutations in the CYB5A gene have thus far only been described in genetic males who presented with methemoglobinemia and 46,XY disorders of sex development (DSD) due to 17,20-lyase deficiency.
A 24-year-old Chinese woman presented to the hematology outpatient clinic with purplish discoloration of fingers, toes, and lips since childhood. Investigations confirmed methemoglobinemia. A homozygous c.105C&gt;G (p.Tyr35Ter) nonsense mutation was detected in the CYB5A gene. Hormonal studies showed isolated 17,20-lyase deficiency. Interestingly, she had a completely normal female phenotype with no DSD, normal pubertal development, and spontaneous pregnancy giving birth uneventfully to a healthy female infant.
The sex hormone-related features of genetic females with 17,20-lyase deficiency due to cytochrome b5 gene mutation appear to differ from that of females with 17,20-lyase deficiency caused by other genetic defects who presented with hypergonadotropic hypogonadism and infertility and differ from genetic males with the same mutation.
R&D Portfolio Management: the case study of a big energy company in Brazil
Authors: Pfitzner Mariana Savedra , Carvalho Ruy de Quadros 
Published: November 2019

DOI: http://dx.doi.org/10.13071/regec.2317-5087.2012.1.1.4038.74-94Portfolio Management entails the systematic evaluation, selection and prioritization of R&D projects in the organizational context. The aim of this article is to discuss the use of tools for managing the R&D portfolio in the Brazilian electricity sector, using the case study of an energy distribution company as an analytical support. In this sector, investment in research projects and guidelines for their completion are enforced by law. Otherwise, energy companies would not invest in R&D, they would rather buy equipment and systems from international suppliers. The execution of these projects is also strongly supervised by ANEEL, which guarantees that their results will turn into new products, patents, job creation, tariff reduction and operational efficiency for the company. If projects do not accomplish with government criteria, energy companies may be strongly penalized. In order to avoid such risk, companies may implement Portfolio Management tools.
Expediente
Authors: Santos Glicia Vieira dos 
Published: November 2019

DOI: http://dx.doi.org/10.13071/regec.2317-5087.2012.1.1.4899.1-4Apresenta a edição de lançamento da Revista Gestão & Conexões (Management and Connections Journal), v1, n1, jul./dez. 2012.
Acessibilidade sob Diferentes Pontos de Vista: caminhos percorridos pelo pesquisador com deficiência visual
Authors: Arnais Magali Aparecida de Oliveira , Stadoan Diego de Bernardin , Zattera Vilson 
Published: November 2019

DOI: http://dx.doi.org/10.13071/regec.2317-5087.2014.3.1.5051.92-106. As tecnologias evoluem em ritmo acelerado, no entanto a acessibilidade para as pessoas com deficiência visual ainda não está devidamente considerada no ambiente acadêmico. Este artigo objetiva apresentar relatos individuais, escritos a partir da percepção de dois alunos/pesquisadores com deficiência visual, usuários do Laboratório de Acessibilidade da Biblioteca Central Cesar Lattes da Universidade Estadual de Campinas (LAB/BCCL/Unicamp), como recurso para aprofundar o conhecimento sobre acessibilidade no ambiente acadêmico. Três aspectos no quesito acessibilidade são apontados por esses usuários: a arquitetônica, a comunicacional levando-se em conta o uso das novas tecnologias e a atitudinal. O aluno/pesquisador com deficiência visual no ensino superior aprende caminhos alternativos para atingir seus objetivos, aponta desde ações de políticas públicas na criação de instrumentos diferentes para uma mesma finalidade às atitudes pró ativas na construção do conceito de acessibilidade.
Towards a Decological Praxis
Authors: Nogueira-Godsey Elaine 
Published: November 2019

Abstract in English
In this paper, I argue that social justice cannot be fully realized without affirming its intrinsic ties to environmental justice, and further that these ties point toward a ‘decological praxis.‘ Decological praxis is a truncation of decolonial ecological pedagogy. It is a praxis that I am crafting and one which I propose that those concerned with justice-oriented theological education can have in common, as it offers possibilities to partake in a progressively shared intersectional decolonial theological methodology. It is decolonial because this is a practice focused in training the mind to emancipate oneself, the other and nature from long-standing hierarchical patterns of power reproducing colonial modes of relationships. I propose that we use decological praxis as the orienting principle to teach, research and learn from each other's experiences of social and environmental injustice. I conclude by proposing that this praxis may result in a culture of decoloniality, which brings into light the need to investigate the effects of coloniality in our own, temporal and local, lived experiences and to do so via a process of deliberate self-reflexivity.

Key words: Environmental Justice, Ecofeminism, Theology, Coloniality, Decolonial Pedagogical Praxis.
The Mountain of Youth: Converting American Buddhism and the Authority of the Monk-Convert Paradigm
Authors: Baker Drew 
Published: November 2019

Abstract English
This article examines generational shifts in popular narratives pertaining to dominant formations of Buddhism in the United States from 1950 to the 1990s through a postcolonial lens particularly sensitive to age, children, and family dynamics. A close read of Jack Kerouac's novels and the film Little Buddha identifies important features of this genealogy. This analysis shows that white Buddhist American converts' power and visibility have been reinforced by the Orientalist notion of a monk-convert lineage which presents the convert—represented as a free white young adult—as the sole heroic incarnation of the present and future of Buddhism in the modern world.

Key words: Buddhism, Conversion, Religion and Age, Orientalism
Usage of plasmapheresis in combined therapy of diabetics
Authors: Sokolov Ye. I. , Podachina S. V. , Zabotnov V. I. , Zanina Ye. B. 
Published: November 2019

Clinical observations have repeatedly proved that myocardial infarction in patients with diabetes mellitus (DM) is much more difficult, gives greater mortality, its complications such as acute heart failure, arrhythmia, and relapses are more often observed. The basis of the atherosclerotic process both in diabetes and without it, the main place is given to hyperlipoproteinemia (hypercholesterolemia, hypertriglyceridemia and hypoalpha-cholesterolemia). Most patients with severe type I diabetes mellitus (insulin-dependent, IDDM) and type II diabetes mellitus (non-insulin-dependent, NIDDM) showed an increase in plasma levels of low and very low density lipoprotein cholesterol (cholesterol-LDL and cholesterol-VLDL, respectively) and a decrease high density lipoprotein cholesterol (HDL-C; anti-atherogenic factor).
The use of lipid-lowering drugs for the correction of hyperlipoproteinemia in patients with diabetes is often ineffective or the effect obtained is short-term in nature, side reactions often develop. In recent years, in order to reduce the level of lipids in blood plasma (coronary heart disease, familial hypercholesterolemia, etc.), extracorporeal methods aimed at massive removal of the plasma lipid pool have begun to be used. According to the authors, the rapid and massive removal of atherogenic lipid fractions from plasma contributes to the release of the steroid from the tissue pool.
In the pathogenesis of the development of vascular complications in patients with IDDM and NIDDM, a significant place is given to dysfunction of erythrocyte membranes. Functional disorders are directly dependent on violations of the structure of membrane lipids. Changes in the structure of the lipid bilayer of the erythrocyte membrane in patients with diabetes contribute to increased microviscosity of membranes, reduced deformability, and hinder their passage through the microcirculation system, which can be the cause of tissue hypoxia and one of the links in the pathogenesis of angiopathy in patients with diabetes.
The aim of this work was to study the possible correction of the lipid spectrum of blood plasma and erythrocyte membranes in patients with diabetes when the plasmapheresis method is included in the complex therapy.