bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on the dietary pattern and local isotopes of the Xiaoshuangqiao Shang Dynasty (1400 bc) site in China
Authors: Wang Ning , Tao Siyuan , Li Suting , Si Yi , Li Hongfei , Song Guo Ding 
Published: June 2020

AbstractHere, we investigate human diet and origins using carbon and nitrogen stable isotope ratios at the site of Xiaoshuangqiao in Henan Province, which dates to the middle Shang Dynasty (1435–1412 cal bc). A total of the 66 specimens (51 humans, six cattle, five pigs, three sheep and one dog) were isotopically analysed for δ13C and δ15N values. The population (δ13C = −9.1 ± 1.5‰, n = 51) was found to consume a predominately C4 diet (millet), and no difference was observed between the δ13C (p = 0.809) and δ15N (p = 0.876) results of the males and females. The isotopic results were then examined by burial location to determine the presence of the local Shang population or sacrificed Dongyi warriors. Differences in δ13C were found for individuals buried in the sacrificial pits H66 (−10.0 ± 1.2‰; n = 9) and H63 (−8.2 ± 0.8‰; n = 11) as well as layer ④ (−8.9 ± 1.5‰; n = 24), with the differences statistically significant for pits H66 and H63 (p = 0.001). The isotopic and archaeological evidence suggests that the individuals recovered in pit H63 and layer ④ were Shang but that the pit H66 skeletons were Dongyi prisoners of war that were sacrificed. As the site of Xiaoshuangqiao is thought to be the lost Shang capital of Ao ‘傲’, this research offers new information about the diet and inhabitants of this city.
Perceptive whole‐body planning for multilegged robots in confined spaces
Authors: Buchanan Russell , Wellhausen Lorenz , Bjelonic Marko , Bandyopadhyay Tirthankar , Kottege Navinda , Hutter Marco 
Published: June 2020

AbstractLegged robots are exceedingly versatile and have the potential to navigate complex, confined spaces due to their many degrees of freedom. As a result of the computational complexity, there exist no online planners for perceptive whole‐body locomotion of robots in tight spaces. In this paper, we present a new method for perceptive planning for multilegged robots, which generates body poses, footholds, and swing trajectories for collision avoidance. Measurements from an onboard depth camera are used to create a three‐dimensional map of the terrain around the robot. We randomly sample body poses then smooth the resulting trajectory while satisfying several constraints, such as robot kinematics and collision avoidance. Footholds and swing trajectories are computed based on the terrain, and the robot body pose is optimized to ensure stable locomotion while not colliding with the environment. Our method is designed to run online on a real robot and generate trajectories several meters long. We first tested our algorithm in several simulations with varied confined spaces using the quadrupedal robot ANYmal. We also simulated experiments with the hexapod robot Weaver to demonstrate applicability to different legged robot configurations. Then, we demonstrated our whole‐body planner in several online experiments both indoors and in realistic scenarios at an emergency rescue training facility. ANYmal, which has a nominal standing height of 80 cm and a width of 59 cm, navigated through several representative disaster areas with openings as small as 60 cm. Three‐meter trajectories were replanned with 500 ms update times.
Effects of land‐cover transitions on emerging aquatic insects and environmental characteristics of headwater streams in an agricultural catchment
Authors: Goss Charles W. , Sullivan S. Mažeika P. , Goebel P. Charles 
Published: June 2020

AbstractStreams and their adjacent riparian zones are increasingly viewed as interdependent systems linked by reciprocal exchanges of energy, organisms, and materials. We assessed potential associations between the emerging aquatic insect flux and transitions between agricultural land and forest fragments to better understand these stream‐riparian linkages in managed landscapes. We sampled stream environmental conditions and emerging insects at 28 sites distributed along three streams flowing through agriculture‐forest‐agriculture transitions in central Ohio, USA, in the summer of 2012. Ephemeroptera and Trichoptera (ET) taxa had higher flux densities in forests (mean and 95% CI: 0.3 insects m−2 d−1 [0.1, 0.8]) compared to agriculture (mean and 95% CI: 0 insect m−2 d−1 [0, 0.1]; p = .004), and ET taxa were found in 67% of forested sites compared to only 15% of agricultural sites. In contrast, Dolichopodidae were more strongly associated with agricultural land (mean and 95% CI: 0.6 insect m−2 d−1 [0.3 to 1.2]) than forests (mean and 95% CI: 0.1 insects m−2 d−1 [0.1, 0.2]; p = .002). Although Chironomidae were the most numerically abundant, ET taxa were among the larger bodied insects and comprised >30% of the total biomass flux, illustrating the importance of taxonomic traits in mediating flux dynamics. Mechanisms driving emerging insect flux were related to substrate grain‐size distribution, channel width, and nutrient concentrations. Overall, our results demonstrate that small forest fragments are strongly related to the aquatic‐to‐terrestrial insect flux and thus have important implications for terrestrial biodiversity and food webs in agricultural landscapes.
CD34+ cell therapy significantly reduces adverse cardiac events, health care expenditures, and mortality in patients with refractory angina
Authors: Johnson Grace L. , Henry Timothy D. , Povsic Thomas J. , Losordo Douglas W. , Garberich Ross F. , Stanberry Larissa I. , Strauss Craig E. , Traverse Jay H. 
Published: June 2020

Abstract
Patients with refractory angina who are suboptimal candidates for further revascularization have improved exercise time, decreased angina frequency, and reduced major adverse cardiac events with intramyocardial delivery of CD34+ cells. However, the effect of CD34+ cell therapy on health care expenditures before and after treatment is unknown. We determined the effect of CD34+ cell therapy on cardiac-related hospital visits and costs during the 12 months following stem cell injection compared with the 12 months prior to injection. Cardiac-related hospital admissions and procedures were retrospectively tabulated for patients enrolled at one site in one of three double-blinded, placebo-controlled CD34+ trials in the 12 months before and after intramyocardial injections of CD34+ cells vs placebo. Fifty-six patients were randomized to CD34+ cell therapy (n = 37) vs placebo (n = 19). Patients randomized to cell therapy experienced 1.57 ± 1.39 cardiac-related hospital visits 12 months before injection, compared with 0.78 ± 1.90 hospital visits 12 months after injection, which was associated with a 62% cost reduction translating to an average savings of $5500 per cell therapy patient. Patients in the placebo group also demonstrated a reduction in cardiac-related hospital events and costs, although to a lesser degree than the CD34+ group. Through 1 January 2019, 24% of CD34+ subjects died at an average of 6.5 ± 2.4 years after enrollment, whereas 47% of placebo patients died at an average of 3.7 ± 1.9 years after enrollment. In conclusion, CD34+ cell therapy for subjects with refractory angina is associated with improved mortality and a reduction in hospital visits and expenditures for cardiac procedures in the year following treatment.
Periodate Oxidation of Carboxymethyl Cellulose under Controlled Conditions
Authors: Zhang Yunfeng , Zhang Linlin , Shao Shengjuan , Chang Xiliang , Li Min 
Published: June 2020

AbstractIn this study, we synthesized dialdehyde carboxymethyl cellulose (DCMC) based on the oxidation reaction of periodate (i. e., Malaprade reaction) in acidic conditions. The primary factors on the synthesis of DCMC were explored based on a 3×3 orthogonal optimization experiment using the reaction temperature, material ratio, and pH, as variables. we identified an optimum DCMC synthetic condition based on the analysis of the production yield and aldehyde content in the final product. The results showed that the impacts of the three factors on the synthesis of DCMC adhered to the order of pH > temperature > material ratio. Synthesis conditions involved pH value of 3.0, reaction temperature of 30 °C, a mass ratio of NaIO4 and CMC of 1 : 1, and a reaction time of 4 h. Which yielded a dialdehyde DCMC content of 79.04 %. By characterizing the carboxymethyl cellulose (CMC) and DCMC samples with Fourier‐transform infrared spectroscopy, X‐ray diffraction, thermogravimetric analysis, and scanning electron microscopy, we confirmed the production of DCMC from the reaction and the crystallinity and thermal stability of CMC reduced when it was oxidized to DCMC.
Copper‐Mediated Intramolecular Oxidative α‐Functionalization of Ugi Precursor: An Efficient Synthesis of Highly Functionalized 2H‐Benzo[e][1,3]oxazin‐4(3H)‐one Derivatives
Authors: Singh Deepti , Pandey Shashi , Chouhan Pradeep Singh , Kant Ruchir , Chauhan Prem M. S. 
Published: June 2020

AbstractA novel and efficient procedure for the synthesis of highly substituted 2H‐benzo[e][1,3]oxazin‐4(3H)‐one is reported. The strategy utilizes Ugi four‐component reaction (Ugi‐4CR) methodology to afford Ugi adduct having free hydroxyl (‐OH) functional group followed by Cu/base mediated regioselective intramolecular dehydrogenative (sp3) C−O bond coupling. The prepared scaffolds are found in a number of pharmaceutically relevant scaffolds such as DRF‐2519 and CX‐614 which is potential in discovery of treatment for Parkinson's disease and Alzheimer's disease respectively.
Pattern Stimulated CVD Growth of 2D MoS2
Authors: Xu Zhuhua , Lv Yanfei , Li Jingzhou , Wei Guodan , Zhao Shichao 
Published: June 2020

AbstractGreat efforts have been explored to prepare monolayer MoS2 through chemical vapor deposition (CVD) method. However, there still were many shortages in CVD method. Herein, with the mixture of MoS2 powders and sodium thiosulfate (Na2S2O3) powders as two precursors, monolayer MoS2 has been successfully grown at a temperature as low as 500 °C through a convenient pattern stimulated CVD growth method in combination with a pattern transfer process. The triangular, hexagonal and larger‐scale monolayer MoS2 have been obtained distributing on both sides of the precursor. Our analysis indicates that the thickness and shape of the spatially separated domains are the function of the distance to the patterned precursor, resulting from different concentration of precursors and atomic ratio of Mo : S. The atomic ratio of Mo : S near to 1 : 2 was beneficial to the preparation of larger‐scale monolater MoS2. The intensity and peak shifting of PL demonstrated the defects and strain in monolayer MoS2. This facile patterned stimulated growth strategy has paved a pioneering way to obtain high quality 2D materials.
Cryo‐Transferred Ultrathin and Stretchable Epidermal Electrodes
Authors: Fang Yunsheng , Li Yue , Wang Xin , Zhou Zhengui , Zhang Kui , Zhou Jun , Hu Bin 
Published: June 2020

AbstractA simple cryo‐transfer method to fabricate ultrathin, stretchable, and conformal epidermal electrodes based on a combination of silver nanowires (AgNWs) network and elastomeric polymers is developed. This method can temporarily enable the soft elastomers with much higher elastic modulus and dimensional contraction through exploiting their glass‐transition behaviors. During this process, a much higher Von Mises stress can be loaded on AgNWs than usual, and the generated strong grip force can facilitate the complete transfer of AgNWs. Afterward, the thawed AgNWs and elastomer composites quickly recover to their soft state at room temperature. The obtained ultrathin and soft electrode with a thickness of 8.4 µm and transmittance of 90.8% at a sheet resistance of 13.2 Ω sq−1can tolerate a stretching strain of 70% and 50 000 repeated bending cycles, which meets rigorous requirements of epidermal applications. The as‐prepared epidermal electrodes are effective and comfortable for electrophysiological signal monitoring, and while showing excellent performance exceeding the commercialized gel electrodes.
Upper Toarcian (Lower Jurassic) marine gastropods from the Cleveland Basin, England: systematics, palaeobiogeography and contribution to biotic recovery from the early Toarcian extinction event
Authors: Ferrari Mariel , Little Crispin T. S. , Atkinson Jed W. 
Published: June 2020

AbstractHere we describe a new upper Toarcian (Lower Jurassic) marine gastropod fauna from rocks of the Cleveland Basin exposed on the North Yorkshire coast of England. The fossil assemblage consists of 16 species, of which three are new:Katosira?bicarinatasp. nov.,Turritelloidea stephenisp. nov. andStriactaenonina eleganssp. nov. Four species are described in open nomenclature asTricarilda? sp.,Jurildasp.,Cylindrobullinasp. andCossmanninasp. The other species have previously been described:Coelodiscus minutus(SchüblerinZieten),Procerithium quadrilineatum(Römer),Pseudokatosira undulata(Benzinvon Zieten),Palaeorissoinaaff.acuminata(Gründel),Pietteia unicarinata(Hudleston),Globulariacf.canina(Hudleston),Striactaeoninacf.richterorumSchulbert & Nützel,Striactaenoninaaff.tenuistriata(Hudleston) andSulcoactaeon sedgvici(Phillips). Most of these species are the earliest records of their respective genera and show palaeobiogeographical connections with contemporary gastropod associations from other regions of Europe and South America. The taxonomic composition of the upper Toarcian Cleveland Basin gastropod assemblage differs substantially from the faunas of the upper Pliensbachian and lower ToarcianTenuicostatumZone, showing the strong effect of the early Toarcian mass extinction event on the marine gastropod communities in the basin. Only a few gastropod species are shared between the late Toarcian faunas and the much more diverse Aalenian gastropod faunas in the Cleveland Basin, suggesting that there was a facies control on gastropod occurrences at that time. This is also a potential explanation for the taxonomic differences between the late Toarcian gastropod faunas in the Cleveland Basin and those in France, and northern and southern Germany.
The Kato Square Root Problem for Divergence Form Operators with Potential
Authors: Bailey Julian 
Published: June 2020

AbstractThe Kato square root problem for divergence form elliptic operators with potential $$V : {\mathbb {R}}^{n} \rightarrow {\mathbb {C}}$$V:Rn→C is the equivalence statement $$\left\| \left( L + V \right) ^{\frac{1}{2}} u \right\| _{2} \simeq \left\| \nabla u \right\| _{2} + \left\| V^{\frac{1}{2}} u \right\| _{2}$$L+V12u2≃∇u2+V12u2, where $$L + V := - \mathrm {div} (A \nabla ) + V$$L+V:=-div(A∇)+V and the perturbation A is an $$L^{\infty }$$L∞ complex matrix-valued function satisfying an accretivity condition. This relation is proved for any potential with range contained in some positive sector and satisfying $$\left\| \left| V \right| ^{\frac{\alpha }{2}} u \right\| _{2} + \left\| (-\Delta )^{\frac{\alpha }{2}}u \right\| _{2} \lesssim \left\| \left( \left| V \right| - \Delta \right) ^{\frac{\alpha }{2}}u \right\| _{2}$$Vα2u2+(-Δ)α2u2≲V-Δα2u2 for all $$u \in D(\left| V \right| - \Delta )$$u∈D(V-Δ) and some $$\alpha \in (1,2]$$α∈(1,2]. The class of potentials that will satisfy such a condition is known to contain the reverse Hölder class $$RH_{2}$$RH2 and $$L^{\frac{n}{2}}\left( {\mathbb {R}}^{n} \right) $$Ln2Rn in dimension $$n > 4$$n>4. To prove the Kato estimate with potential, a non-homogeneous version of the framework introduced by Axelsson, Keith and McIntosh for proving quadratic estimates is developed. In addition to applying this non-homogeneous framework to the scalar Kato problem with zero-order potential, it will also be applied to the Kato problem for systems of equations with zero-order potential.
Colouring simplicial complexes via the Lechuga–Murillo’s model
Authors: Méndez David 
Published: June 2020

AbstractLechuga and Murillo showed that a non-oriented, simple, connected, finite graph G is k-colourable if and only if a certain pure Sullivan algebra associated to G and k is not elliptic. In this paper, we extend this result to simplicial complexes by means of several notions of colourings of these objects.
Digital health for optimal supportive care in oncology: benefits, limits, and future perspectives
Authors: Aapro M. , Bossi P. , Dasari A. , Fallowfield L. , Gascón P. , Geller M. , Jordan K. , Kim J. , Martin K. , Porzig S. 
Published: June 2020

Abstract
Background
Digital health provides solutions that capture patient-reported outcomes (PROs) and allows symptom monitoring and patient management. Digital therapeutics is the provision to patients of evidence-based therapeutic interventions through software applications aimed at prevention, monitoring, management, and treatment of symptoms and diseases or for treatment optimization. The digital health solutions collecting PROs address many unmet needs, including access to care and reassurance, increase in adherence and treatment efficacy, and decrease in hospitalizations. With current developments in oncology including increased availability of oral drugs and reduced availability of healthcare professionals, these solutions offer an innovative approach to optimize healthcare resource utilization.

Design
This scoping review clarifies the role and impact of the digital health solutions in oncology supportive care, with a view of the current segmentation according to their technical features (connection to sensors, PRO collection, remote monitoring, self-management in real time…), and identifies evidence from clinical studies published about their benefits and limitations and drivers and barriers to adoption. A qualitative summary is presented.

Results
Sixty-six studies were identified and included in the qualitative synthesis. Studies supported the use of 38 digital health solutions collecting ePROs and allowing remote monitoring, with benefits to patients regarding symptom reporting and management, reduction in symptom distress, decrease in unplanned hospitalizations and related costs and improved quality of life and survival. Among those 38 solutions 21 provided patient self-management with impactful symptom support, improvement of QoL, usefulness and reassurance. Principal challenges are in developing and implementing digital solutions to suit most patients, while ensuring patient compliance and adaptability for use in different healthcare systems and living environments.

Conclusions
There is growing evidence that digital health collecting ePROs provide benefits to patients related to clinical and health economic endpoints. These digital solutions can be integrated into routine supportive care in oncology practice to provide improved patient-centered care.
Prevalence and Predictors of Sexual Difficulties and Associated Distress Among Partnered, Sexually Active Older Women in Norway, Denmark, Belgium, and Portugal
Authors: Graham Cynthia A. , Štulhofer Aleksandar , Lange Theis , Hald Gert Martin , Carvalheira Ana A. , Enzlin Paul , Træen Bente 
Published: June 2020

AbstractThere has been little comparative, cross-cultural research on sexual difficulties and associated distress, and factors associated with these, among older women. Therefore, the aim of this study was to investigate prevalence rates of sexual difficulties, distress related to these difficulties, and associated sociodemographic, relational, and health factors, among sexually active older women (60–75 years) in committed relationships across four European countries (Norway, Denmark, Belgium, and Portugal). These data could inform us about what differentiates women who do and do not experience distressing sexual difficulties and facilitate the identification of older women who might benefit from clinical interventions as well as the development of new interventions. In total, 1057 women (357 Norwegian; 322 Danish; 237 Belgian; 141 Portuguese) completed a cross-sectional questionnaire assessing six sexual difficulties—vaginal dryness, orgasmic difficulties, lacking interest in sex, lacking enjoyment in sex, pain during sex, and no excitement/arousal during sex—and associated distress. We found a high prevalence of sexual difficulties lasting 3 months or longer in the past year (between 23.5 and 50.2%, depending on the specific difficulty). With the exception of vaginal dryness and pain during sex, however, the majority of women reporting sexual difficulties (50.0% to 86.1%, depending on the specific difficulty) reported no or mild distress. There were relatively few cross-country differences, either in the prevalence of sexual difficulties or related distress. Few sociodemographic or health variables were associated with distressing sexual difficulties, but higher sexual intimacy, higher emotional intimacy, and better mental health were associated with less distress about some sexual difficulties. The findings underline the importance of healthcare professionals asking older women about sexual function and especially associated distress, and suggest that careful attention to the psychological and relationship context of these sexual difficulties is needed, as these could be important targets in the treatment process.
Coronavirus as a Catalyst to Transform Consumer Policy and Enforcement
Authors: Riefa C. 
Published: June 2020

AbstractA review of the unfair commercial practices (including price gouging) that have emerged in the context of the pandemic lead us to reflect on how effective consumer law enforcement is at this juncture. This article calls for the pandemic to act as a catalyst to review the way consumer law has so far approached markets and their regulation. It argues that now, more than ever, consumer law needs to protect the vulnerable and public enforcement mechanisms must be able to prevent harm as much as possible rather than repair it. Fairness should be by design and not something that is offered to consumers simply as a remedy. The article explores some viable solutions to effect this transformation of consumer policy and enforcement beyond the pandemic.
On the Extension of the Kiyotaki and Wright model to Transformable Goods
Authors: Bourgeois-Gironde Sacha , Czupryna Marcin 
Published: June 2020

AbstractIn this paper we extend the classical Kiyotaki and Wright (KW) model and consider a transformable good. Such an extension enables us to adapt the model to the specific conditions of the wine market. The most important change, with respect to the original model, is that one type of good (young wine, in our model) can improve its quality and thereby transform to another type of good (old wine). However, there is a certain probability that such transformation may not be successful and the good under consideration may simply spoil. We adapt the main KW theoretical features to the study of speculative strategies in a stylized wine market. This study can be generalized to other commodity markets in which goods are unstable and present intrinsic properties such as quality increase or decrease across time. These markets are also typically characterized by roles or types of agents, such as producers, merchants and consumers, whose interests lack double coincidence when they meet. We define a general model and then use simulation methods to systematically study under which conditions speculative strategies are possible in this setting and which is the most efficient distribution of types of agents under speculative equilibria. The theoretical results are also provided for the model, with equal numbers of agents of different types, similarly to the Kiyotaki and Wright original paper.