bluuebunny/crossref_metadata_2025_split huggingface dataset:
Telecontroller design for renewable wind energy systems
Authors: Rasyid A , Purwandi A W , Mustafa L D , Junus M , Aisah A , Ronilaya F , Ilyas M D M 
Published: January 2020

Abstract
The problem of geographical position in Indonesia is that there are still many villages in Indonesia that have not been able to receive PLN electricity flow. People in these remote villages can indeed enjoy electricity with their own efforts to buy diesel/premium/gas-fueled electricity generators, etc., from non-renewable fuels that are expensive and difficult to get to meet lighting needs at night. Therefore, we designed the wind power generation system for the needs of residential homes that can be controlled electronically and monitored via Cell Phones with WiFi transmission which is currently affordable at the title “Tele controller Design for Renewable Wind Energy Systems”. The system that we have designed can control the distribution of electric current in the same direction or for electric current that has been converted to alternating current, as well as the system can monitor to determine the characteristics of the wind and the resulting electrical output. The results of this study are expected to make it easier for the community in each house to generate electricity independently to be able to meet the needs of cheap night lighting and without environmental problems. With a system that is always monitored and controlled, it is expected to always be maintained and with maintenance that is easily protected from damage, it can eventually increase the service life.
Utilization of wireless technology for sound communication using TMS320 C6713
Authors: Zakaria M N , Sarosa M , Junus M , Suja’i M S , Isnomo Y H P 
Published: January 2020

Abstract
The development of communication technology, both on algorithms and devices has been so rapid. The application of communication devices that previously used radio signal (wireless) would be more efficient if cable (on wire) is used instead. With a large number of buildings with wide locations, there are still many spaces that are not reachable by communication devices. Therefore, it is necessary to add a new communication tool that can be used to convey information in the campus environment intended for announcements, from one place to another or from one room to another simultaneously, both with point to multipoint as well as point to point characteristic which is suitable for internal communication and emergency situations. This wireless network can be expanded without using a cable backbone. In addition, with the equal sharing of access rights, the network will be more effective because it can be done anywhere as long as there is still a network connection. Audio effects can be applied in real time using DSP (Digital Signal Processing) Starter Kit TMS320C6713 by implementing in the equipment. In the audio input signal of 0.050 Vpp there is no change in the frequency of the original signal that is 1 Khz there is a change in the intensity of the sound produced 0.364 Vpp, 2 kHz to 0.280 Vpp while 3 kHz to 0.236 Vpp. There is a change in amplitude while the output frequency approaches the original signal frequency.
Prepaid water meter card based on internet of things
Authors: Taufik M , Rakhmania A E , Afnani Y N 
Published: January 2020

Abstract
Indonesian population has grown rapidly, as shown in Central Statistics Agency report that in 2018, Indonesia’s population reached 265 million. Along with the increasing number of populations, water for daily needs is in high demand. A good monitoring and water management is needed to oversee the water usage efficiently. Currently, local water company still implements post-paid payment system that is time and human resources inefficient. In this study, we proposed the implementation of internet of things (IoT) in designing prepaid water meter card for real time water usage monitoring. The card could also be used to directly purchase water quota online via website. The proposed water meter used air vent valve system combined with the water flow sensor to measure the amount of user’s water usage. Result shows that the proposed system could work properly with the error value of 2.84% measured from the difference between water flows read in conventional water meter with the measured value in our proposed water meter. The purchased quota will be directly deducted based on the amount of measured water usage. The process was done in real time environment and the data will be automatically stored in server. When user is running out of quota, solenoid valve embedded in the proposed water meter system will be automatically closed such that user have no access to water source.
Analysis of information technology governance in the planning and organization of e-learning at Universitas Negeri Malang
Authors: Sutadji E , Hidayat W N , Patmanthara S , Sulton S , Jabari N A M , Irsyad M 
Published: January 2020

Abstract
Learning paradigm in the 21st century has changed, so that the utilization of information and communication technology in education is absolutely necessary. E-learning becomes one of the alternatives that bring together technological support with the current learning needs. Universitas Negeri Malang (UM) is one of the universities that have a concentration on the implementation and development of e-learning for the implementation of education. The development of e-learning based learning should be balanced with evaluation or audit of the information system so that threats or losses can be avoided or prevented. This study aims to determine the extent to which e-learning performance of the UM viewed from the governance of information technology in planning and organization on e-learning using COBIT 4.1 framework and provide recommendation governance improvement after knowing the gap between the current governance with the expected governance. Data collection techniques were conducted with interviews and questionnaires with UM e-learning managers. Data analysis method is done through mapping of maturity level of planning and organization of information technology governance by using descriptive analysis. The result of research mentioned that maturity level of planning and organization of information technology governance of UM e-learning, which is at level 1.88 which means that managers have realized the need of IT development and formation of more professional organization. The GAP analysis between expected conditions and current conditions averages 1.12. Recommendations that can be given to the development of e-learning UM is to form organizations and sharpen the vision and mission of system development better.
Production of tachyonic neutrino in matter
Authors: Nanni Luca 
Published: January 2020

Abstract
Recently, a new theory based on superluminal tunnelling has been proposed to explain the transition of highly energetic neutrinos propagating in matter to tachyonic states. In this work, we determine the possible mechanisms that lead neutrinos into a superluminal realm based on the assumption that ultrarelativistic neutrinos travelling in matter lose part of their energy with the emission of Bremsstrahlung radiation. The obtained photons, in turn, can create neutrino-antineutrino pairs, one or both of which can be superluminal. We also prove that pair creation may occur with neutrino flavour oscillation provided that only one of them is a space-like particle. This suggests that mass oscillation and superluminal behaviour could be related phenomena. Finally, using the generalised Lorentz transformations, we formulate the Lagrangian of the kinematically allowed scattering processes. The structure of this Lagrangian is consistent with the formalism of the Standard Model. Based on this Lagrangian, at least one of the particles forming the pair must always be subluminal. The possibility that the pair creation process is mediated by a dark photon is also discussed.
Dipolar hole-blocking layers for inverted perovskite solar cells: effects of aggregation and electron transport levels
Authors: Butscher Julian F , Sun Qing , Wu Yufeng , Stuck Fabian , Hoffmann Marvin , Dreuw Andreas , Paulus Fabian , Hashmi A Stephen K , Tessler Nir , Vaynzof Yana 
Published: January 2020

Abstract
Herein, we report on the synthesis and investigation of two triazino-isoquinoline tetrafluoroborate electrolytes as hole-blocking layers in methylammonium triiodide perovskite photovoltaic devices with fullerene electron extraction layer. We find that increasing the thickness of the dipolar hole-blocking layer results in a gradual increase in the open-circuit voltage suggesting that aggregation of the molecules can enhance the dipole induced by the layer. This finding is confirmed by theoretical calculations demonstrating that while both molecules exhibit a similar dipole moment in their isolated state, this dipole is significantly enhanced when they aggregate. Ultra-violet photoemission spectroscopy measurements show that both derivatives exhibit a high ionization potential of 7 eV, in agreement with their effective hole-blocking nature demonstrated by the devices. However, each of the molecules shows a different electron affinity due to the increased conjugation of one of the derivatives. While the change in electron transport level between the two derivatives is as high as 0.3 eV, the difference in the open-circuit voltage of both types of devices is negligible, suggesting that the electron transport level plays only a minor role in determining the open-circuit voltage of the device. Numerical device simulations confirm that the increase in built-in potential, arising from the high dipole of the electrolyte layer, compensates for the non-ideal energetic alignment of the charge transport levels, resulting in high open-circuit voltages for a range of electron transport levels. Our study demonstrates that the application of small molecule electrolytes as hole-blocking layer in inverted architecture perovskite solar cells is a powerful tool to enhance the open-circuit voltage and provides useful guidelines for designing future generations of such compounds.
Defect-free laser powder bed fusion of Ti–48Al–2Cr–2Nb with a high temperature inductive preheating system
Authors: Caprio Leonardo , Demir Ali Gökhan , Chiari Gianmarco , Previtali Barbara 
Published: January 2020

Abstract
In the industrial panorama, laser powder bed fusion (LPBF) systems enable the near net shaping of metal powders into complex geometries with unique design features. This makes the technology appealing for many industrial applications, which require high performance materials combined with lightweight design, lattice structures and organic forms. However, many of the alloys that would be ideal for the realisation of these functional components are classified as difficult to weld due to their cracking sensitivity. γ-TiAl alloys are currently processed via electron beam melting (EBM) to produce components for energy generation applications. The EBM process provides crack-free processing thanks to the preheating stages between layers, but lacks geometrical precision. The use of LPBF could provide the means for higher precision, and therefore an easier post-processing stage. However, industrial LPBF systems employ resistive heating elements underneath the base plate which do not commonly reach the high temperatures required for the processing of γ-TiAl alloys. Thus, elevated temperature preheating of the build part and control over the cooling rate after the deposition process is concluded are amongst the features which require further investigations. In this work, the design and implementation of a novel inductive high temperature LPBF system to process Ti–48Al–2Cr–2Nb is presented. Specimens were built with preheating at 800 °C and the cooling rate at the end of the build was controlled at 5 °C min−1. Crack formation was suppressed and apparent density in excess of 99% was achieved.
Stability of perovskite PV modules
Authors: Galagan Yulia 
Published: January 2020

Abstract
The stability of perovskite photovoltaics is a very hot topic nowadays because a long lifetime of the devices is one of the main conditions required for the commercialization of perovskite technologies. Although a lot of research on stability has been done on small solar cells, there is not too much information about the stability of the modules. A very important question arises: whether the stability of the modules is different from the stability of the individual cells. With the future goal of scale-up perovskite PV technology, it is important to understand possible the degradation mechanisms which are specific to the modules. This perspective article highlights the stability issues, which are unique to modules but not observed in small cells.
Evaluating anticoagulation sensitivity among elderly patients managed with an institution’s heparin protocol using initial anti-factor Xa levels
Authors: Lemke Adley , Kohs Jean , Weber Lynn 
Published: January 2020

Abstract

Purpose
The purpose of this study was to assess an institution’s heparin protocols in elderly and nonelderly adult populations to see if a response difference was observed.

Methods
This was a retrospective cohort study of hospitalized adults who were prescribed unfractionated heparin due to surgery, acute coronary syndrome (ACS), or deep vein thrombosis/pulmonary embolism (DVT/PE) from February 11, 2016, through August 1, 2017. Patients were divided into nonelderly adults 18 to 69 years of age and elderly patients 70 years of age or older. The anti-factor Xa (anti-Xa) level after protocol initiation was compared to the institution’s goal range of 0.3 to 0.7 IU/mL. Outcomes of each protocol in the elderly population were compared to outcomes in their nonelderly counterparts to determine if there was a difference in heparin response.

Results
A total of 325 patients were included in the analysis, comprising 150 elderly and 175 nonelderly adults. Elderly patients had a higher initial anti-Xa levels than did their nonelderly adult counterparts in the ACS, DVT/PE, and surgery protocols, with P values of 0.02, &lt;0.001, and 0.01, respectively. Only the ACS protocol demonstrated increased frequency of above-target-level anti-Xa levels in the elderly (P = 0.03).

Conclusion
Elderly patients had significantly higher initial anti-Xa levels than did nonelderly adult patients across all protocols. This study identifies the need to further study elderly patients’ increased heparin sensitivity to determine if a separate dosing protocol is needed.
Genome anchoring to nuclear landmarks drives functional compartmentalization of the nuclear space
Authors: Canat Antoine , Veillet Adeline , Bonnet Amandine , Therizols Pierre 
Published: January 2020

Abstract
The spatial organization of the genome contributes to essential functions such as transcription and chromosome integrity maintenance. The principles governing nuclear compartmentalization have been the focus of considerable research over the last decade. In these studies, the genome–nuclear structure interactions emerged as a main driver of this particular 3D genome organization. In this review, we describe the interactions between the genome and four major landmarks of the nucleus: the nuclear lamina, the nuclear pores, the pericentromeric heterochromatin and the nucleolus. We present the recent studies that identify sequences bound to these different locations and address the tethering mechanisms. We give an overview of the relevance of this organization in development and disease. Finally, we discuss the dynamic aspects and self-organizing properties that allow this complex architecture to be inherited.
idenPC-MIIP: identify protein complexes from weighted PPI networks using mutual important interacting partner relation
Authors: Wu Zhourun , Liao Qing , Liu Bin 
Published: January 2020

AbstractProtein complexes are key units for studying a cell system. During the past decades, the genome-scale protein–protein interaction (PPI) data have been determined by high-throughput approaches, which enables the identification of protein complexes from PPI networks. However, the high-throughput approaches often produce considerable fraction of false positive and negative samples. In this study, we propose the mutual important interacting partner relation to reflect the co-complex relationship of two proteins based on their interaction neighborhoods. In addition, a new algorithm called idenPC-MIIP is developed to identify protein complexes from weighted PPI networks. The experimental results on two widely used datasets show that idenPC-MIIP outperforms 17 state-of-the-art methods, especially for identification of small protein complexes with only two or three proteins.
Cortical interneuron-mediated inhibition delays the onset of amyotrophic lateral sclerosis
Authors: Khademullah C Sahara , Aqrabawi Afif J , Place Kara M , Dargaei Zahra , Liang Xinyi , Pressey Jessica C , Bedard Simon , Yang Jy Wei , Garand Danielle , Keramidis Iason , Gasecka Alicja , Côté Daniel , De Koninck Yves , Keith Julia , Zinman Lorne , Robertson Janice , Kim Jun Chul , Woodin Melanie A 
Published: January 2020

Abstract
Amyotrophic lateral sclerosis is a fatal disease resulting from motor neuron degeneration in the cortex and spinal cord. Cortical hyperexcitability is a hallmark feature of amyotrophic lateral sclerosis and is accompanied by decreased intracortical inhibition. Using electrophysiological patch-clamp recordings, we revealed parvalbumin interneurons to be hypoactive in the late pre-symptomatic SOD1*G93A mouse model of amyotrophic lateral sclerosis. We discovered that using adeno-associated virus-mediated delivery of chemogenetic technology targeted to increase the activity of the interneurons within layer 5 of the primary motor cortex, we were able to rescue intracortical inhibition and reduce pyramidal neuron hyperexcitability. Increasing the activity of interneurons in the layer 5 of the primary motor cortex was effective in delaying the onset of amyotrophic lateral sclerosis-associated motor deficits, slowing symptom progression, preserving neuronal populations, and increasing the lifespan of SOD1*G93A mice. Taken together, this study provides novel insights into the pathogenesis and treatment of amyotrophic lateral sclerosis.
Neuropeptide S Displays as a Key Neuromodulator in Olfactory Spatial Memory
Authors: Wang Can , Xin Le , Cai Chen-Chen , Cong Chao-Yu , Xie Jun-Fan , Kong Xiang-Pan , Dong Chao-Yu , Li Jing , Cui Guang-Fu , Chen Hai-Lin , Ren Yan-Li , Shao Yu-Feng , Hou Yi-Ping 
Published: January 2020

Abstract
Neuropeptide S (NPS) is an endogenous peptide recently recognized to be presented in the brainstem and believed to play an important role in maintaining memory. The deletion of NPS or NPS receptor (NPSR) in mice shows a deficit in memory formation. Our recent studies have demonstrated that central administration of NPS facilitates olfactory function and ameliorates olfactory spatial memory impairment induced by muscarinic cholinergic receptor antagonist and N-methyl-D-aspartate receptor antagonist. However, it remains to be determined if endogenous NPS is an indispensable neuromodulator in the control of the olfactory spatial memory. In this study, we examined the effects of NPSR peptidergic antagonist [D-Val5]NPS (10 and 20 nmol, intracerebroventricular) and nonpeptidergic antagonist SHA 68 (10 and 50 mg/kg, intraperitoneal) on the olfactory spatial memory using computer-assisted 4-hole-board olfactory spatial memory test in mice. Furthermore, immunofluorescence was employed to identify the distributions of c-Fos and NPSR immunoreactive (-ir) neurons in olfactory system and hippocampal formation known to closely relate to the olfactory spatial memory. [D-Val5]NPS dosing at 20 nmol and SHA 68 dosing at 50 mg/kg significantly decreased the number of visits to the 2 odorants interchanged spatially, switched odorants, in recall trial, and simultaneously reduced the percentage of Fos-ir in NPSR-ir neurons, which were densely distributed in the anterior olfactory nucleus, piriform cortex, subiculum, presubiculum, and parasubiculum. These findings suggest that endogenous NPS is a key neuromodulator in olfactory spatial memory.
TeaMiD: a comprehensive database of simple sequence repeat markers of tea
Authors: Dubey Himanshu , Rawal Hukam C , Rohilla Megha , Lama Urvashi , Kumar P Mohan , Bandyopadhyay Tanoy , Gogoi Madhurjya , Singh Nagendra Kumar , Mondal Tapan Kumar 
Published: January 2020

Abstract
Tea is a highly cross-pollinated, woody, perennial tree. High heterozygosity combined with a long gestational period makes conventional breeding a cumbersome process. Therefore, marker-assisted breeding is a better alternative approach when compared with conventional breeding. Considering the large genome size of tea (~3 Gb), information about simple sequence repeat (SSR) is scanty. Thus, we have taken advantage of the recently published tea genomes to identify large numbers of SSR markers in the tea. Besides the genomic sequences, we identified SSRs from the other publicly available sequences such as RNA-seq, GSS, ESTs and organelle genomes (chloroplasts and mitochondrial) and also searched published literature to catalog validated set of tea SSR markers. The complete exercise yielded a total of 935 547 SSRs. Out of the total, 82 SSRs were selected for validation among a diverse set of tea genotypes. Six primers (each with four to six alleles, an average of five alleles per locus) out of the total 27 polymorphic primers were used for a diversity analysis in 36 tea genotypes with mean polymorphic information content of 0.61–0.76. Finally, using all the information generated in this study, we have developed a user-friendly database (TeaMiD; http://indianteagenome.in:8080/teamid/) that hosts SSR from all the six resources including three nuclear genomes of tea and transcriptome sequences of 17 Camellia wild species.
Database URL: http://indianteagenome.in:8080/teamid/
Fatal outcome of first case of Streptococcus sinensis in infective endocarditis in the Netherlands: a case report
Authors: van Ommen Anne Margje Lisa Naomi , Slavenburg Serena , Diepersloot Rob , de Vries Feyens Cornelia Adriana 
Published: January 2020

Abstract

Background
Infective endocarditis is a relatively common disease in a cardiologist’s daily practice. Nowadays more detailed information about pathogens is provided to us by diagnostics such as MALDI Biotyper Massa Spectrometer. We present a case of endocarditis lenta in which Streptococcus sinensis was identified in the Netherlands for the first time.

Case summary
A 58-year-old man was admitted with high suspicion of endocarditis lenta complicated by severe kidney dysfunction and anaemia. He was treated with penicillin and gentamycin. Transthoracic echocardiogram revealed a large vegetation at the mitral valve and MALDI Biotyper Massa Spectrometer (Microflex) revealed S. sinensis as the pathogen. The patient refused to receive blood transfusions or surgery. Due to cerebral infarction with haemorrhagic transformation, the patient died 8 days after admission.

Discussion
Streptococcus sinensis was described in Hong Kong for the first time and is associated with endocarditis in rheumatic heart disease. To our knowledge, this is the first case reporting a fatal outcome of endocarditis due to this bacterium in the acute phase. In this case, late discovery, disease severity, and under treatment all contributed to the poor outcome. We want to share the knowledge on the existence of this bacteria.