bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uncovering the failure of Agile framework implementation using SSM-based action research
Authors: Suryaatmaja Kevin , Wibisono Dermawan , Ghazali Achmad , Fitriati Rachma 
Published: January 2020

AbstractIt is undeniable that the Agile software development (SD) framework has been commonly used in information technology projects. However, many of the early adopters failed to implement it properly. Some researchers had proposed a solution by using the adaptation framework as a support, but they cannot clearly explain its development. Furthermore, the correlation between adaptation framework and problem solving is dubious. This study reviews and discusses the literature and empirical studies on the failure of Agile SD implementation by revisiting the supporting framework that used to comprehend the issues in Agile SD implementation. A comparative approach is used to review the literature available in academic databases, such as ProQuest, EBSCO, IEEE, and Scopus, to ensure research originality and novelty. By filtering 87 papers that met the initial criteria, only 4 researchers focused on the area of knowledge management and used the learning process as a supporting framework in Agile SD implementation. However, they did not clearly explain the development of the framework for Agile SD. The author’s initial research on a corporation reveals the failure of Agile SD implementation. Soft systems methodology (SSM)-based action research (AR) proposed to identify the real issues in Agile SD implementation. SSM-based AR provides a solution by clarifying the development of a framework using tacit and explicit knowledge to validate the development process. This study can help practitioners and academics understand the process of Agile SD implementation by early adopters who still need assistance with its application. This study is the first to explore Agile SD implementation in a corporation using the experience-based approach, contributing to knowledge improvement. It contributes to the scholarly literature by presenting concepts that combine human-centric aspects and knowledge management to improve the learning in the organization.
Global warming accelerates uptake of atmospheric mercury in regions experiencing glacier retreat
Authors: Wang Xun , Luo Ji , Yuan Wei , Lin Che-Jen , Wang Feiyue , Liu Chen , Wang Genxu , Feng Xinbin 
Published: January 2020

SignificanceIn this study, we identify a process that recaptures atmospheric Hg in glacier-retreated areas driven by global warming. Melting of glaciers is known to release Hg originally locked in ice into the atmosphere and downstream ecosystems. Recession of glaciers promotes rapid establishment of vegetative ecosystems that capture more atmospheric Hg over the long run than the Hg released from glacier melting. The increased vegetative biomass driven by climate change can result in significant changes in global Hg cycling.
RAP80 and BRCA1 PARsylation protect chromosome integrity by preventing retention of BRCA1-B/C complexes in DNA repair foci
Authors: Vohhodina Jekaterina , Toomire Kimberly J. , Petit Sarah A. , Micevic Goran , Kumari Geeta , Botchkarev Vladimir V. , Li Zhe , Livingston David M. , Hu Yiduo 
Published: January 2020

Significance
Normally, BRCA1 promotes physiological, error-free homologous recombination repair (HRR) of damaged DNA and genome stability. In contrast, excessive, deregulated HRR can lead to genome instability. The BRCA1-binding protein RAP80 restricts HRR amplitude and genome instability, at least in part by manifesting polyubiquitin and poly-ADP-ribose binding activities in postdamage nuclear foci. Although how these processes operate in detail remains unknown, we find that simultaneous defects in RAP80/BRCA1 complex formation and in BRCA1 poly-ADP-ribosylation result in the persistent accumulation of BRCA1-containing complexes in nuclear foci that also contain CtIP and BACH1. These effects lead to excessive HRR, chromosomal hyper-recombination, and gross chromosomal abnormalities.
Apex structures enhance water drainage on leaves
Authors: Wang Ting , Si Yifan , Dai Haoyu , Li Chuxin , Gao Can , Dong Zhichao , Jiang Lei 
Published: January 2020

Significance
Liquid manipulation is of significance not only for industrial spraying and drainage facilities, but also for the survival of creatures. Plant leaves perform excellently in rainwater drainage and leaf drying at the apex to avoid damage. Here we demonstrate that apex structure enhances water shedding with high dripping frequencies and low retention volumes. Based on the understanding of the tiny apex structure in controlling water delivery at the plant leaf, the evolutionary law of leaf apex shape could be further revealed. The shape-controlled liquid manipulation mechanism would improve the microfluidic and drainage systems.
Climate change and the opportunity cost of conflict
Authors: Roche Kevin R. , Müller-Itten Michèle , Dralle David N. , Bolster Diogo , Müller Marc F. 
Published: January 2020

Significance
There is growing consensus among academics that climate change may amplify the risk of violent conflicts. While underlying mechanisms are poorly understood, negative income shocks associated with climate variability have been long hypothesized to play an important role. We relate recent hydrologic and microeconomic advances to investigate the theoretical foundation of this claim. Results prescribe caution in interpreting empirical relations between climate variability and conflict in the context of climate change. While fighting preferentially occurs during climate anomalies, more frequent anomalies may not yield more conflicts. By shifting the entire distribution of rainfall, climate change effectively redefines the very notion of climate anomaly. Adaptation to this new normal can have a dominant, and often counterintuitive, effect on conflict probability.
Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA–GABA transmission in highly addicted rats
Authors: Kallupi Marsida , Carrette Lieselot L. G. , Kononoff Jenni , Solberg Woods Leah C. , Palmer Abraham A. , Schweitzer Paul , George Olivier , de Guglielmo Giordano 
Published: January 2020

Significance
More than 2 million individuals in the United States currently have a substance use disorder that is related to prescription opioid pain relievers. We identified individual differences in oxycodone addiction-like behaviors in outbred heterogenous stock rats with high and low addiction-like behaviors. We found that the downregulation of nociceptin levels in the central nucleus of the amygdala (CeA) may be responsible for hyper–γ-aminobutyric acid (GABA)ergic tone in the CeA that is observed in individuals who develop addiction-like behaviors. The development of small molecules that target the nociceptin system may have therapeutic efficacy for the treatment of opioid use disorder.
A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo
Authors: Covés-Datson Evelyn M. , King Steven R. , Legendre Maureen , Gupta Auroni , Chan Susana M. , Gitlin Emily , Kulkarni Vikram V. , Pantaleón García Jezreel , Smee Donald F. , Lipka Elke , Evans Scott E. , Tarbet E. Bart , Ono Akira , Markovitz David M. 
Published: January 2020

Significance
There is a pressing need for new antiinfluenza therapeutic agents. We show that a molecularly engineered banana lectin (carbohydrate-binding protein) has broad-spectrum activity against all influenza strains tested, including drug-resistant and currently circulating strains; is safe upon repeated administration in mice; and, moreover, is efficacious at treating lethal influenza infection via clinically pertinent routes of administration. We demonstrate that the lectin binds to the viral hemagglutinin glycoprotein and exerts its primary antiviral effect via inhibition of an early stage of the viral life cycle, viral membrane fusion to the host endosomal membrane. Our findings indicate that this engineered lectin, which has a mechanism of action quite distinct from the presently available agents, has potential as an antiinfluenza agent.
CK1α, CK1δ, and CK1ε are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis
Authors: Hanna-Addams Sarah , Liu Shuzhen , Liu Hua , Chen She , Wang Zhigao 
Published: January 2020

Significance
Necroptosis is a form of cell death implicated in many human diseases. A series of requirements has to be fulfilled before the cell makes the ultimate decision to die. One such essential event in necroptosis is the phosphorylation of RIPK3. It has previously been suggested that RIPK3 might phosphorylate itself. Here we discover that CK1 family kinases directly phosphorylate RIPK3. In cells without CK1 proteins, RIPK3 is not phosphorylated and the cells remain alive when exposed to necroptosis-inducing signals. Additionally, when cells express a form of RIPK3 which cannot be recognized by CK1, the cells also remain alive. This work defines a step in the necroptosis pathway and identifies potential targets for intervening necroptosis-associated diseases.
Language industry views on the profile of the post-editor
Authors: Cid Clara Ginovart , Colominas Carme , Oliver Antoni 
Published: January 2020

Abstract
The more language service companies (LSCs) include machine translation post-editing (MTPE) in their workflows, the
more important it is to know how the PE task is performed, who the post-editors are, and what skills they should have. This
research is designed to address such questions. It aims to deepen our knowledge of current practices to later create new training
content and adapt existing training methodologies to different types of audiences. Based on the results of a survey of LSCs and
other companies who currently use MTPE, we present a picture of evolving practices in the contemporary European MTPE market, and
opinions held about this emerging métier. Our research finds that a high level of expertise in MTPE may not
necessarily be indicative of the industry, and that the post-editor of MT has a multi- and transdisciplinary profile.
Expression of two glutamate decarboxylase genes in Lactobacillus brevis during gamma-aminobutyric acid production with date residue extract
Authors: Hasegawa Momoko , Fujii Sotaro , Funato Kouichi , Yoshida Atsushi , Sambongi Yoshihiro 
Published: January 2020

Abstract

Gamma-aminobutyric acid (GABA) is produced by Lactobacillus brevis using date residue fermentation. In this study, the GABA production method was improved, for which L. brevis strain JCM 1059T was the most efficient among the four L. brevis strains examined. This was presumably due to a difference in the expression level of the gene encoding glutamate decarboxylase that catalyzes GABA synthesis.

Abbreviation
GABA: gamma-aminobutyric acid
Global warming to increase violent crime in the United States
Authors: Harp Ryan D , Karnauskas Kristopher B 
Published: January 2020

Abstract
Recent studies have revealed large and robust correlations between seasonal climate and violent crime rates at regional scales within the continental United States, begging the question of how future climate change will influence violent crime rates. Here, we combine empirical models from previous studies with 42 state-of-the-art global climate models to make such projections, while accounting for key factors like regionality and seasonality, and appropriately combining multiple of sources of uncertainty. Our results indicate that the United States should expect an additional 3.2 [2.1–4.5] or 2.3 [1.5–3.2] million violent crimes between 2020 and 2099, depending on greenhouse gas emissions scenario. We also reveal critical dependencies of these violent crime projections on various global warming targets, such as those associated with the Paris Agreement (1.5 °C and 2 °C). These results emphasize the often-overlooked socially-mediated impacts of climate change on human health, with an estimated economic cost of $5 billion annually.
Nonadiabatic escape and stochastic resonance
Authors: Moon W , Balmforth N , Wettlaufer J S 
Published: January 2020

Abstract
We analyze the fluctuation-driven escape of particles from a metastable state under the influence of a weak periodic force. We develop an asymptotic method to solve the appropriate Fokker–Planck equation with mixed natural and absorbing boundary conditions. The approach uses two boundary layers flanking an interior region; most of the probability is concentrated within the boundary layer near the metastable point of the potential and particles transit the interior region before exiting the domain through the other boundary layer, which is near the unstable maximal point of the potential. The dominant processes in each region are given by approximate time-dependent solutions matched to construct the approximate composite solution, which gives the rate of escape with weak periodic forcing. Using reflection we extend the method to a double well potential influenced by white noise and weak periodic forcing, and thereby derive a two-state stochastic model—the simplest treatment of stochastic resonance theory—in the nonadiabatic limit.
Comparative analysis of various heating sources for individual dwellings
Authors: Moroz M V , Podbelskaya D N 
Published: January 2020

Abstract
In the modern world there is a huge variety of different options for heating systems that we can use in the design and construction of residential buildings. The choice of the most economically and technically advantageous heating system plays a big role for the further comfortable living of people. The article discusses the performance and cost effectiveness of various heating systems using modern materials and technologies in the conditions of the city of Irkutsk. Based on the calculations made, we performed an analysis of heating systems with various heat sources using the example of both classic water heating systems and various sources of electric heating from the already widespread underfloor heating to the less common infrared heating systems. We also considered the possibility of using alternative energy sources to cover the consumption of electricity when using electric heating.
The complex mobile independent power station for the recreational areas
Authors: Tunik A A , Tolstoy M Y , Kalashnikov M P 
Published: January 2020

Abstract
There are many problems with energy supply and waste water utilization of recreational areas associated with increased environmental requirements and restrictions. These areas include the Baikal Lake, there are many settlements and tourist campings around. The use of traditional energy and wastewater systems at these sites is problematic. In the result of the our research a complex mobile independent power station was developed, which will allow to solve the above problems. This installation includes renewable energy equipment, which allows to receive electricity and heat energy, as well as utilize the wastewater.
Predictive assessment of man-made risks during oil-handling operations at tank farms
Authors: Drozdova T I , Vereshchagina A S 
Published: January 2020

Abstract
Predictive analysis of events associated with the depressurization of the tank during the filling of fuel showed the probability of the occurrence and development of fires resulting from the spread of clouds of flammable gases with concentrations corresponding to the concentration limits of ignition. It is shown that when fuel ignites with the development of a pool fire or when an air shock wave propagates as a result of an explosion of the fuel-air mixture, the damaging factors will have a negative effect, which will lead to destruction and damage to the operating personnel.
Preparation of product for environmentally friendly plant protection
Authors: Gorelova O M , Kurtukova L V , Rusakov S G 
Published: January 2020

Abstract
The paper discusses environmentally friendly ways to improve the productivity of crop production. Drugs made from plants containing terpenes are capable to protect crops from various diseases and stimulate their development. Outer bark of birch may contain triterpene alcohol betulin up to 40% of the mass, which allows to obtain environmentally friendly plant protection products. Experimental studies are devoted to studying the process of extracting betulin from birch bark, creating a betulin-containing preparation “Stimulin” for treating seeds and vegetative plants, as well as testing “Stimulin” on various agricultural cultures. The results of the use of the drug showed a significant increase in yield (by 8-35 %%) of crops such as wheat, barley, buckwheat, soybeans, and watermelons. The test of the fungicidal activity of “Stimulin” was carried out on sea buckthorn, the main causative agent of diseases and the cause of drying of which is the Fusarium mushroom. The fungicidal activity of “Stimulin” is comparable to potent synthetic agrochemicals.
Health risk assessment for people consuming agricultural products grown in the zone of aluminum production
Authors: Ivanova S V , Ryabchikova I A 
Published: January 2020

Abstract
Most of the Russian people consume products grown in their gardens located near large industrial centers. Toxic substances can enter the human body together with agricultural products grown on polluted land. The article aims to assess carcinogenic and non-carcinogenic risks to health of people consuming agricultural products (root and tuber crops) grown in the area affected by aluminum production (the Southern Baikal region). The risk was assessed using a model developed by U.S.EPA. The carcinogenic risk for average concentrations of benz(a)pyrene in vegetables was CR=1.09·10-4. The value is between maximum permissible and unacceptable levels. The chronic non-carcinogenic risk exceeds the safe value four times (HI = 4.15) due to large doses of iron (HQ=2.47) and nickel (HQ=0.88). The total value of the hazard coefficient for fluorine (HQ=0.74) entering the human body with root and tuber crops does not exceed the permissible level, despite the fact that it is one of the main components of soil pollution near aluminum production plants.
Wastewater treatment and application in the advanced nanofiltration system
Authors: Junussova L R , Chicherin S V 
Published: January 2020

Abstract
The Aral Sea Region is characterized by being a very demanding consumer of industrial wastewater treatment. We studied the effects of various pretreatment methods on aluminum production. This method can be used as an alternative one in industrial wastewater treatment. The aim of multi-year study is to explore a nanofiltration as a one of the most attractive technologies for this application since nanofiltration membranes can retain ions and small organic molecules from an aqueous solution. But it is also very challenging due to the presence of salts and operating problems such as fouling, salt deposition, etc. Result becomes available thank to experimental set-up based on an ion exchange and a reverse osmosis. Results are also verified by evaluation tests and field applications showing their usage and wastewater conversion efficiency. The technological scheme includes combined water treatment plant using desalination technology and additional block functioning for an aluminum production and a temporary storage. Aluminum is to be produced of the Syr Darya river rich of it with the help of cutting-edge technology of oxide film removal and cartridge packing. This work evaluates the use of aluminum accumulated in the reaction unit by means of aluminum powder plus water module to reduce the pollutant contents of industrial wastewater quickly and effectively. The invention makes it possible to reduce the cost of aluminum by 3-4 times. Energy consumption of the desalination process was also discussed. Extracted aluminum is a superior material for industry. The high activity of aluminum to water is prohibited by a thin layer of aluminum oxide on its surface. The water treatment system with a combined phase purification and desalination may contribute up to 50 per cent to meeting the reduction of energy consumption for end product (aluminum).
Interrelation of regulatory legal acts regulating professional functions of the labor protection specialist
Authors: Sevastyanov B V , Lisina E B , Selyunina N V , Shadrin R O , Shalamova A V 
Published: January 2020

Abstract
The work shows the history of the development of the profession of a specialist in the field of labor protection. For the first time in the Russian Empire the training of specialists in the field of labor protection took place in the beginning of the 20th century at the Peter the Great Institute, St. Petersburg. In this paper the professional duties of a specialist in the field of labor protection specified in current regulatory legal acts are considered, including working in commissions on labor protection, accident investigation, drafting documents, orders, plans and reports relating to labor protection and providing advice to heads of departments and enterprises about issues in labor protection. It is indicated they have organizational, managerial and supervisory content. The analysis of the content of professional competencies of the Federal State Educational Standard of Higher Education “Technospheric safety” and the labor functions of a specialist in the field of labor protection is presented. It is indicated that some of the academic disciplines included in educational programs are very distantly related to the activities of a labor protection specialist. At the same time, academic disciplines arising from the professional duties of a labor protection specialist are not included in the curricula, which indicates the need for a substantial adjustment of the content of the educational standard for technospheric safety and, above all, towards a more complete account of those functions that are imposed by current regulatory legal acts on specialists of labor protection services organizations. The list of professionally orienteering disciplines that should be included in the curriculum for preparing students in the “Technospheric safety” training area is presented.
Study of Occupational Health Risks in the Irkutsk Region
Authors: Podkorytova A M , Khamidullina E A 
Published: January 2020

Abstract
The aim of this article is to study the statistical patterns of changes in the level of industrial risks in the Irkutsk Region and to identify the factors that have the greatest influence on these changes. In the paper, we used statistical analysis methods, such as retrospective analysis, construction of Shewhart control charts, and regression analysis. The retrospective analysis included the period of 2011-2017 and was carried out in the Irkutsk Region in general and by separate industries. The Shewhart control charts were constructed by type of injury in order to identify the randomness/systemic nature of the causes of damage to workers’ health. The linear regression analysis was used to identify dependencies of the level of industrial injuries on the costs of labor protection measures. It was shown that, in the Irkutsk Region in general, the risks of injury and death of workers in the workplace tended to decrease during 2011-2017. But only since 2014 there has been an increase in the ratio of injuries to deaths, which indicates a real reduction in the severity of injuries. Statistical modeling using the construction of Shewhart control charts showed that there were systematic causes in respect to non-fatal injuries and, accordingly, the need to identify them. In terms of fatal injuries, we noted statistical risk controllability and natural variability inherent in random processes. Models of the linear dependency of the level of industrial injuries on the costs of labor protection measures revealed a high reverse causality between the risk of industrial injuries and the costs of training in labor protection. The results obtained indicate the need to increase the interest of employers in quality training in labor protection, as well as the importance of optimizing the costs to ensure occupational safety.