bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond forests in the Amazon: biogeography and floristic relationships of the Amazonian savannas
Authors: Devecchi Marcelo F , Lovo Juliana , Moro Marcelo F , Andrino Caroline O , Barbosa-Silva Rafael G , Viana Pedro L , Giulietti Ana Maria , Antar Guilherme , Watanabe Maurício T C , Zappi Daniela C 
Published: March 2020

AbstractOpen habitats such as grasslands occupy &lt; 5% of the Amazon and are currently grouped under the broad term Amazonian savanna, covering an area of c. 267 000 km2, mostly in Brazil and Bolivia. These habitats are found isolated within an extensive rainforest matrix, having a distinct flora from the latter. The lower Amazon River is home to several patches of savanna that occupy both south and north banks of the river, in Santarém, Alenquer and Monte Alegre. Although having an abundance of herbaceous plants, most studies on these open areas focus only on tree species, ignoring the relevant non-woody component of the vegetation. Our objectives were to provide new surveys of seed plants for two Amazonian savanna sites and to take the opportunity to revisit the biogeographical links between Amazonian savanna, Amazonian canga vegetation and the central Brazilian cerrado (CBC) and caatinga, analysing woody and herbaceous plants. We created a floristic database that includes sites of Amazonian savannas, including campinarana, coastal scrub (restinga), CBC and Amazonian campos rupestres (on canga or other substrate). We compared those sites using multivariate analyses to find out the degree of floristic resemblance between sites. We prepared a new list of 406 species of seed plants [336 in Parque Estadual de Monte Alegre (PEMA) and 117 in Serra do Itauajuri (SI)], including 23 new records for the state of Pará and some putative new species for science. The Amazonian savannas form three loosely arranged groups, whereas the Amazonian canga formed a cohesive assemblage. Both groups were contrasted against cerrado and caatinga sites and had a distinctive flora from both. Sites from north-western Pará (Alter do Chão, PEMA and SI) were grouped with their northern counterparts in Roraima. An improved representation of the flora of these sites is provided, with more insight into the relationship between the Amazonian savanna sites and other vegetation types. It is worrying that recent changes of the Brazilian legislation place open environments, such as PEMA, in the path of vulnerability to disturbance and destruction.
COVID-19 Transmission Within a Family Cluster by Presymptomatic Carriers in China
Authors: Qian Guoqing , Yang Naibin , Ma Ada Hoi Yan , Wang Liping , Li Guoxiang , Chen Xueqin , Chen Xiaomin 
Published: March 2020

Abstract
We report a family cluster of coronavirus disease 2019 (COVID-19) caused by a presymptomatic case. There were 9 family members, including 8 laboratory-confirmed with COVID-19, and a 6-year-old child had no evidence of infection. Among the 8 patients, 1 adult and a 13-month-old infant were asymptomatic, and 1 adult was diagnosed as having severe pneumonia.
The Treaty as to Commercial Relations of 1903: China and Extraterritoriality
Authors: Soffe Raphaëlle P 
Published: March 2020

Abstract
The history of United States and Chinese intellectual property relations formally began with the signing of the Treaty as to Commercial Relations in 1903. The next three years saw the Chinese government frequently present revised versions of the 1903 Treaty’s implementation terms, with the 1905 Shangpu Draft responding to foreign merchant requests by removing its commitment to extraterritoriality—a regime whereby Western citizens in China were subject solely to the laws of their own country and not to Chinese laws. In this article, I document the intellectual property violations by Americans and Europeans in China, and how the legal case made by China for the removal of extraterritoriality, specifically for intellectual property violations, was a sign in itself that China was increasingly attentive to the mechanisms and constraints involved in legal reform. The collapse of the negotiations in 1906 would serve as a critical juncture in the commitment and interest of China to pursue intellectual property reform, with the US and China not signing another treaty concerning copyright until 1946. The refusal by the US to compromise on extraterritoriality contributed, in part, to the ‘four decades of inaction’ in intellectual property affairs.
Effect of altitude on mortality of end-stage renal disease patients on hemodialysis in Peru
Authors: Bravo-Jaimes Katia , Loescher Viky Y , Canelo-Aybar Carlos , Rojas-Camayo Jose , Mejia Christian R , Schult Sandra , Nieto Ruben , Singh Kyra , Messing Susan , Hinostroza Juana 
Published: March 2020

Abstract

Background
In Latin America, the prevalence of end-stage kidney disease (ESKD) has risen tremendously during the last decade. Previous studies have suggested that receiving dialysis at high altitude confers mortality benefits; however, this effect has not been demonstrated at &gt;2000 m above sea level (masl) or in developing countries.

Methods
This historical cohort study analyzed medical records from six Peruvian hemodialysis (HD) centers located at altitudes ranging from 44 to 3827 masl. Adult ESKD patients who started maintenance HD between 2000 and 2010 were included. Patients were classified into two strata based on the elevation above sea level of their city of residence: low altitude (&lt;2000 masl) and high altitude (≥2000 masl). Death from any cause was collected from national registries and Cox proportional hazards models were built.

Results
A total of 720 patients were enrolled and 163 (22.6%) resided at high altitude. The low-altitude group was significantly younger, more likely to have diabetes or glomerulonephritis as the cause of ESKD and higher hemoglobin. The all-cause mortality rate was 84.3 per 1000 person-years. In the unadjusted Cox model, no mortality difference was found between the high- and low-altitude groups {hazard ratio [HR] 1.20 [95% confidence interval (CI) 0.89–1.62]}. After multivariable adjustment, receiving HD at high altitude was not significantly associated with higher mortality, but those with diabetes as the cause of ESKD had significantly higher mortality [HR 2.50 (95% CI 1.36–4.59)].

Conclusions
In Peru, patients receiving HD at high altitudes do not have mortality benefits.
Larval density affects phenotype and surrounding bacterial community without altering gut microbiota in Drosophila melanogaster
Authors: Henry Y , Tarapacki P , Colinet H 
Published: March 2020

ABSTRACTLarval crowding represents a complex stressful situation arising from inter-individual competition for time- and space-limited resources. The foraging of a large number of individuals may alter the chemical and bacterial composition of food and in turn affect individual's traits. Here we used Drosophila melanogaster to explore these assumptions. First, we used a wide larval density gradient to investigate the impact of crowding on phenotypical traits. We confirmed that high densities increased development time and pupation height, and decreased viability and body mass. Next, we measured concentrations of common metabolic wastes (ammonia, uric acid) and characterized bacterial communities, both in food and in larvae, for three contrasting larval densities (low, medium and high). Ammonia concentration increased in food from medium and high larval densities, but remained low in larvae regardless of the larval density. Uric acid did not accumulate in food but was detected in larvae. Surprisingly, bacterial composition remained stable in guts of larvae whatever their rearing density, although it drastically changed in the food. Overall, these results indicate that crowding deeply affects individuals, and also their abiotic and biotic surroundings. Environmental bacterial communities likely adapt to altered nutritional situations resulting from crowding, putatively acting as scavengers of larval metabolic wastes.
Full-waveform-based characterization of acoustic emission activity in a mine-scale experiment: a comparison of conventional and advanced hydraulic fracturing schemes
Authors: Niemz Peter , Cesca Simone , Heimann Sebastian , Grigoli Francesco , von Specht Sebastian , Hammer Conny , Zang Arno , Dahm Torsten 
Published: March 2020

SUMMARYUnderstanding fracturing processes and the hydromechanical relation to induced seismicity is a key question for enhanced geothermal systems (EGS). Commonly massive fluid injection, predominately causing hydroshearing, are used in large-scale EGS but also hydraulic fracturing approaches were discussed. To evaluate the applicability of hydraulic fracturing techniques in EGS, six in situ, multistage hydraulic fracturing experiments with three different injection schemes were performed under controlled conditions in crystalline rock at the Äspö Hard Rock Laboratory (Sweden). During the experiments the near-field ground motion was continuously recorded by 11 piezoelectric borehole sensors with a sampling rate of 1 MHz. The sensor network covered a volume of 30×30×30 m around a horizontal, 28-m-long injection borehole at a depth of 410 m. To extract and characterize massive, induced, high-frequency acoustic emission (AE) activity from continuous recordings, a semi-automated workflow was developed relying on full waveform based detection, classification and location procedures. The approach extended the AE catalogue from 196 triggered events in previous studies to more than 19 600 located AEs. The enhanced catalogue, for the first time, allows a detailed analysis of induced seismicity during single hydraulic fracturing experiments, including the individual fracturing stages and the comparison between injection schemes. Beside the detailed study of the spatio-temporal patterns, event clusters and the growth of seismic clouds, we estimate relative magnitudes and b-values of AEs for conventional, cyclic progressive and dynamic pulse injection schemes, the latter two being fatigue hydraulic fracturing techniques. While the conventional fracturing leads to AE patterns clustered in planar regions, indicating the generation of a single main fracture plane, the cyclic progressive injection scheme results in a more diffuse, cloud-like AE distribution, indicating the activation of a more complex fracture network. For a given amount of hydraulic energy (pressure multiplied by injected volume) pumped into the system, the cyclic progressive scheme is characterized by a lower rate of seismicity, lower maximum magnitudes and significantly larger b-values, implying an increased number of small events relative to the large ones. To our knowledge, this is the first direct comparison of high resolution seismicity in a mine-scale experiment induced by different hydraulic fracturing schemes.
The multilevel identity politics of the 2019 Eurovision Song Contest
Authors: Press-Barnathan Galia , Lutz Naama 
Published: March 2020

Abstract
This article uses the 2019 Eurovision Song Contest (ESC) that took place in Tel Aviv to explore how cultural mega-events serve both as political arenas and as tools for identity construction, negotiation and contestation. These processes of identity politics are all conducted across national–subnational–international–transnational levels. The hosting of mega-events fleshes out these multiple processes in a very strong manner. We first discuss the politics of hosting mega-events in general. We then examine the identity politics associated more specifically with the Eurovision Song Contest, before examining in depth the complex forms of identity politics emerging around the competition following the 2018 Israeli victory. We suggest that it is important to study together the multiple processes—domestic, international and transnational—of identity politics that take place around the competition, as they interact with each other. Consequently, we follow the various stakeholders involved at these different levels and their interactions. We examine the internal identity negotiation process in Israel surrounding the event, the critical actors debating how to use the stage to challenge the liberal, western, ‘normal’ identity Israel hoped to project in the contest and how other stakeholders (participating states, national broadcasting agencies, participating artists) reacted to them, and finally we examine the behaviour of the institution in charge, the European Broadcasting Union, and national governments. We contribute to the study of mega-events as fields of contestation, to the understanding of the complex, multilevel nature of national identity construction, negotiation and contestation in the current era, and more broadly to the role that popular culture plays in this context.
Horror, apocalypse and world politics
Authors: Aistrope Tim , Fishel Stefanie 
Published: March 2020

Abstract
World politics generates a long list of anxiety-inspiring scenarios that threaten to unravel everyday life with sudden and violent destruction. From total war and the concentration camps, through nuclear firestorms, global pandemics and climate disaster, the diabolical violence of the recent past and conceivable future is the stuff of nightmares. Yet International Relations scholars and practitioners are often criticized for being disconnected from the human realities of international calamity. The challenge for both is to engage world politics in a way that foregrounds the human consequences of extreme violence and depravation. In this article, we explore these difficult experiences through popular culture representations of the apocalypse, a subject of intense interest for researchers in a discipline where global destruction is a distinct possibility. However, we take a different route by engaging the apocalypse through the horror genre, the one place where human suffering is explicitly accentuated. We argue that the horror genre is at once an access point for ethical engagement with the human consequences of extreme violence and a complex terrain where dark imaginings can be politically loaded, culturally specific and ethically ambiguous.
Bar Category of Modules and Homotopy Adjunction for Tensor Functors
Authors: Anno Rina , Logvinenko Timothy 
Published: March 2020

Abstract
Given a differentially graded (DG)-category ${{\mathcal{A}}}$, we introduce the bar category of modules ${\overline{\textbf{{Mod}}}-{\mathcal{A}}}$. It is a DG enhancement of the derived category $D({{\mathcal{A}}})$ of ${{\mathcal{A}}}$, which is isomorphic to the category of DG ${{\mathcal{A}}}$-modules with ${A_{\infty }}$-morphisms between them. However, it is defined intrinsically in the language of DG categories and requires no complex machinery or sign conventions of ${A_{\infty }}$-categories. We define for these bar categories Tensor and Hom bifunctors, dualisation functors, and a convolution of twisted complexes. The intended application is to working with DG-bimodules as enhancements of exact functors between triangulated categories. As a demonstration, we develop a homotopy adjunction theory for tensor functors between derived categories of DG categories. It allows us to show in an enhanced setting that given a functor $F$ with left and right adjoints $L$ and $R$, the functorial complex $FR \xrightarrow{F{\operatorname{act}}{R}} FRFR \xrightarrow{FR{\operatorname{tr}} - {\operatorname{tr}}{FR}} FR \xrightarrow{{\operatorname{tr}}} {\operatorname{Id}}$ lifts to a canonical twisted complex whose convolution is the square of the spherical twist of $F$. We then write down four induced functorial Postnikov systems computing this convolution.
LncRNA SDHAP1 confers paclitaxel resistance of ovarian cancer by regulating EIF4G2 expression via miR-4465
Authors: Zhao Hui , Wang Aixia , Zhang Zhiwei 
Published: March 2020

Abstract
Ovarian cancer has ranked as one of the leading causes of female morbidity and mortality around the world, which affects ∼239,000 patients and causes 152,000 deaths every year. Chemotherapeutic resistance of ovarian cancer remains a devastating actuality in clinic. The aberrant upregulation of long non-coding RNA succinate dehydrogenase complex flavoprotein subunit A pseudogene 1 (lncRNA SDHAP1) in the Paclitaxel (PTX)-resistant ovarian cancer cell lines has been reported. However, studies focussed on SDHAP1 in its regulatory function of chemotherapeutic resistance in ovarian cancer are limited, and the detailed mechanisms remain unclear. In this study, we demonstrated that SDHAP1 was upregulated in PTX-resistant SKOV3 and Hey-8 ovarian cancer cell lines while the level of miR-4465 was downregulated. Knocking-down SDHAP1 induced re-acquirement of chemo-sensitivity to PTX in ovarian cancer cells in vitro. Mechanically, SDHAP1 upregulated the expression of EIF4G2 by sponging miR-4465 and thus facilitated the PTX-induced apoptosis in ovarian cancer cells. The regulation network involving SDHAP1, miR-4465 and EIF4G2 could be a potential therapy target for the PTX-resistant ovarian cancer.
New Seed-Collection Zones for the Eastern United States: The Eastern Seed Zone Forum
Authors: Pike Carolyn , Potter Kevin M , Berrang Paul , Crane Barbara , Baggs Joanne , Leites Laura , Luther Tom 
Published: March 2020

AbstractAbstractReforestation and restoration efforts have traditionally relied on “local” seed sources as planting stock. The term “local” has different meanings in different locales, since no single set of seed-collection zones has yet been widely adopted across the eastern United States. Given concerns about mitigating the effects of climate change, forest managers are increasingly seeking to move seed sources in a process called assisted migration, which would be facilitated if a common set of seed-collection zones were available. We developed a map of 245 seed-collection zones for 37 states by combining two ecologically important layers: plant hardiness zones and ecoregions. These new seed-collection zones should be used by seed collectors and nurseries to describe the origin of seed for plants and trees in the eastern United States. Common garden studies remain the gold standard for determining how far to move seed from any particular seed-collection zone. For species that have not been field-tested, seed movement that is limited either within a seed-collection zone or between adjacent seed-collection zones is a reasonable general guideline.
Characterization of a sweet basil acyltransferase involved in eugenol biosynthesis
Authors: Dhar Niha , Sarangapani Sreelatha , Reddy Vaishnavi Amarr , Kumar Nadimuthu , Panicker Deepa , Jin Jingjing , Chua Nam-Hai , Sarojam Rajani 
Published: March 2020

Abstract
Sweet basil (Ocimum basilicum) plants produce its characteristic phenylpropene-rich essential oil in specialized structures known as peltate glandular trichomes (PGTs). Eugenol and chavicol are the major phenylpropenes produced by sweet basil varieties whose synthetic pathways are not fully elucidated. Eugenol is derived from coniferyl acetate by a reaction catalysed by eugenol synthase. An acyltransferase is proposed to convert coniferyl alcohol to coniferyl acetate which is the first committed step towards eugenol synthesis. Here, we perform a comparative next-generation transcriptome sequencing of different tissues of sweet basil, namely PGT, leaf, leaf stripped of PGTs (leaf–PGT), and roots, to identify differentially expressed transcripts specific to PGT. From these data, we identified a PGT-enriched BAHD acyltransferase gene ObCAAT1 and functionally characterized it. In vitro coupled reaction of ObCAAT1 with eugenol synthase in the presence of coniferyl alcohol resulted in eugenol production. Analysis of ObCAAT1-RNAi transgenic lines showed decreased levels of eugenol and accumulation of coniferyl alcohol and its derivatives. Coniferyl alcohol acts as a common substrate for phenylpropene and lignin biosynthesis. No differences were found in total lignin content of PGTs and leaves of transgenic lines, indicating that phenylpropene biosynthesis is not coupled to lignification in sweet basil.
Plant nitrogen uptake and assimilation: regulation of cellular pH homeostasis
Authors: Feng Huimin , Fan Xiaorong , Miller Anthony J , Xu Guohua 
Published: March 2020

AbstractThe enzymatic controlled metabolic processes in cells occur at their optimized pH ranges, therefore cellular pH homeostasis is fundamental for life. In plants, the nitrogen (N) source for uptake and assimilation, mainly in the forms of nitrate (NO3–) and ammonium (NH4+) quantitatively dominates the anion and cation equilibrium and the pH balance in cells. Here we review ionic and pH homeostasis in plant cells and regulation by N source from the rhizosphere to extra- and intracellular pH regulation for short- and long-distance N distribution and during N assimilation. In the process of N transport across membranes for uptake and compartmentation, both proton pumps and proton-coupled N transporters are essential, and their proton-binding sites may sense changes of apoplastic or intracellular pH. In addition, during N assimilation, carbon skeletons are required to synthesize amino acids, thus the combination of NO3– or NH4+ transport and assimilation results in different net charge and numbers of protons in plant cells. Efficient maintenance of N-controlled cellular pH homeostasis may improve N uptake and use efficiency, as well as enhance the resistance to abiotic stresses.
Health Characteristics of the Madeira Riverine Population
Authors: de Mattos Oliveira Lízia Felix Cotias , Lennon Robert P , Roman John W , Sullivan John F , Milder Edmund A 
Published: March 2020

Abstract

Introduction
The Amazon River Basin is the largest and the most complex fluvial system in the world. The Brazilian government provides dental and medical care to the riverine populations in this region in part through medical assistance missions, conducted by four hospital ships. The Brazilian Navy invited U.S. Navy medical personnel to join the February 2019 mission aboard Navio de Assistência Hospitalar (NAsH) Carlos Chagas to provide care along the Madeira River.

Materials and Methods
In the course of providing primary care services, demographic, health, and dental data of the Madeira Riverine population were collected. Descriptive statistics were used to generate average health and dental data. Chi-square tests were used to compare population prevalence data. Linear regression was used to evaluate dental caries per patient with proximity to nearest large population center and village population. This project was approved by Naval Medical Center Portsmouth Institutional Review Board.

Results
The Madeira Riverine population has similar dental health to Brazilians living in urban centers. Their prevalence of hypertension and diabetes compared favorably with the U.S. averages (17.7% vs. 34.3% [P &lt; 0.001] and 3% vs. 9.4% [P &lt; 0.001], respectively). Based on the most prevalent ICD-10 code diagnoses, future missions can expect high volumes of patients with intestinal parasites, hypertension, common skin infections, women’s health concerns, and musculoskeletal complaints.

Conclusions
This study adds to the limited health data currently available on Brazilian Riverine populations. It demonstrates the effectiveness of the Hospital Assistance missions in providing dental care and documents some unique aspects of Riverine health that warrant further study.