bluuebunny/crossref_metadata_2025_split huggingface dataset:
Applicability of Hydrological Models for Flash Flood Simulation in Small Catchments of Hilly Area in China
Authors: Xin Zhuohang , Shi Ke , Wu Chenchen , Wang Lu , Ye Lei 
Published: January 2020

Abstract
Flash flood in small catchments of hilly area is an extremely complicated nonlinear process affected by catchment properties and rainfall spatio-temporal variation characteristics including many physical-geographical factors, and thus accurate simulation of flash flood is very difficult. Given the fact that hundreds of hydrological models are available in the literature, how to choose a suitable hydrological model remains an unsolved task. In this paper, we selected five widely used hydrological models including three lumped hydrologic models, a semi-distributed hydrological model and a distributed hydrological model for flash flood simulation, and studied their applicability in fourteen typical catchments in hilly areas across China. The results show that the HEC-HMS distributed hydrological model outperforms the other models and is suitable to simulate the flash floods caused by highly intense rainfall. The Dahuofang model (lumped) has higher precision in peak runoff time simulation. However, its performance is quite poor on the flood volume simulation in the small catchments characterized by intense vegetation coverage and highly developed stream network. The Antecedent precipitation index and Xinanjiang models (lumped) can obtain good simulation results in small humid catchments as long as long-term historical precipitation and runoff data are provided. The TOPMODEL also shows good performance in small humid catchments, but it is unable to simulate the flash floods characterized by the rapid rise and recession. Our results could be very beneficial in practice, since these provide a solid foundation in the selection of hydrological model for flash flood simulation in small catchments in hilly area.
Embodiment in concept-based L2 grammar teaching: The case of German light verb constructions
Authors: Suñer Ferran , Roche Jörg 
Published: January 2020

AbstractGerman light verb constructions are especially challenging for advanced L2 learners because of the abstract meaning of the different verbs and the high degree of lexico-grammatical variety. Acknowledging that language is a symbolic system representing humans’ perception of the world and is thus strongly linked to embodied experiences, this study explores the potential of bodily engagement in the form of multimedia animations for leveraging the learning of embodied concepts related to light verb constructions. To this end, thirty-nine French-speaking learners of German were divided into two groups: The first group worked with animations illustrating the embodied nature of light verb constructions and performed specific tasks that set out to trigger mental simulation of relevant embodied concepts; the second group was presented with form-based explanations and completed tasks focusing on the different categories of light verb constructions. The results show that the use of bodily engagement in the form of multimedia animations led to significantly better performance and contributed to some extent to changing students’ attitudes about how grammar can best be learned.
A new record and phylogenetic position ofNotiosorex crawfordi(Eulipotyphla, Soricidae) with distribution in Zacatecas, Mexico, using mitochondrial DNA
Authors: Álvarez-Córdova Fernando , Rosas-Valdez Rogelio , Martínez-Salazar Elizabeth A. 
Published: January 2020

AbstractA unique record of the desert shrew in Zacatecas, Mexico, is known and has been collected since 1897 in the locality “El Plateado” within the municipality of El Plateado de Joaquin Amaro, Zacatecas. On October 2016, two specimens were collected from the municipality of Susticacán, Zacatecas, Mexico. A morphological identification and phylogenetic analysis based on partial sequences of cytochromeboxidase of mitochondrial DNA (mtDNA) were implemented. Morphology and the phylogenetic trees that were recovered by using maximum-likelihood (ML) confirmed the identity of these specimens asNotiosorex crawfordi. This is the second record for the species in Zacatecas, Mexico, after 121 years.
The function of lysosomes and their role in Parkinson’s disease
Authors: Zunke Friederike 
Published: January 2020

Abstract
Lysosomes are cellular organelles that are important for the degradation and recycling of various biomolecules. Specialized lysosomal membrane proteins, as well as soluble enzymes, are important for the efficient turn-over of lysosomal substrates. A deficiency in the degradative capacity of lysosomes leads to severe pathologies referred to as lysosomal storage disorders. There is increasing evidence for the importance of lysosomal function in neurodegenerative disorders, including Parkinson’s disease. One reason for this might be the vulnerability of neuronal cells. Since neurons do not undergo further cell division, non-degraded substrates accumulate in aging cells, causing a buildup of toxicity. Recent genomic screenings identified a number of lysosome-associated genes as potential risk factors for Parkinson’s disease, which are discussed in this review. Moreover, it is outlined how targeting lysosomal function might help in developing novel therapeutic strategies.
Assessment of Sulfate-Induced Heave in Chemically Treated Soils Using a Novel Hybrid Sensor
Authors: Talluri Nagasreenivasu , Congress Surya S. C. , Bheemasetti Tejo V. , Puppala Anand J. , Yu Xiong 
Published: January 2020

Abstract
Highway agencies frequently encounter problems caused by sulfate-induced heave in lime- and cement-treated subgrades. A thorough evaluation of sulfate-related risks for subgrades involves time-consuming laboratory tests. A real-time monitoring of the sulfate heaving phenomenon in the test section in the real field environment would provide a quick performance evaluation of sulfate soils treated with chemical additives. This would help transportation agencies in producing resilient pavements with low maintenance issues. This article presents an innovative hybrid sensor comprising a bender element and time domain reflectometry that can evaluate sulfate-related heave in real time. The new sensor was calibrated in the laboratory by studying the strength and stiffness behavior of three chemically treated high-sulfate soils. Following laboratory calibration, the sensor was embedded in lime-treated field sections, where the changes in moisture and stiffness were monitored simultaneously in real time. Field testing proved that the sensor was able to provide data to assess sulfate-induced heaving in the field. This article details the development of this sensor that can save millions of dollars for transportation agencies in the better stabilization design for sulfate soils.
All-cause mortality in patients with acromegaly treated with pegvisomant: an ACROSTUDY analysis
Authors: Tritos Nicholas A , Mattsson Anders F , Vila Greisa , Biller Beverly M K , Klibanski Anne , Valluri Srinivas , Hey-Hadavi Judith , Kelepouris Nicky , Jimenez Camilo 
Published: January 2020

Objective
To examine all-cause mortality rates in patients with acromegaly on pegvisomant and identify pertinent risk factors, including insulin-like growth factor I (IGF-I).

Design
Retrospective cohort analysis of data from ACROSTUDY (global surveillance study of patients with acromegaly treated with pegvisomant).

Methods
Kaplan–Meier analyses and Cox regression techniques were used to examine survival rates. Standardized mortality ratios (SMR) with reference to general population (WHO GBD 2016) were estimated. Multiplicative multiple Poisson regression models were used to characterize the association between SMR, IGF-I, and other risk factors associated with mortality risk.

Results
The study consisted of 2077 subjects who were followed for a median interval of 4.1 years, contributing to 8957 patient-years. Higher on-treatment IGF-I (P = 0.0035), older attained age (P < 0.0001), and longer duration of acromegaly (>10 years) before starting pegvisomant (P = 0.05) were associated with higher mortality rates. In reference to general population rates, higher SMR (1.10, 1.42, and 2.62, at attained age 55 years) were observed with higher serum IGF-I category (SMR trend: 1.44 (44%)/per fold level of IGF-I/ULN (95% CI: 1.10, 1.87), P = 0.0075). SMR increased per year of younger attained age (1.04 (1.02–1.04), P < 0.0001) and were higher for longer disease duration (>10 years) before starting pegvisomant (1.57 (1.02, 2.43), P = 0.042). Serum IGF-I levels within the normal range during pegvisomant therapy were associated with all-cause mortality rates that were indistinguishable from the general population.

Conclusions
Higher on-treatment IGF-I, older attained age, and longer duration of acromegaly before starting pegvisomant are associated with higher all-cause mortality rates. Younger patients with uncontrolled acromegaly have higher excess all-cause mortality rates in comparison with older patients.
Horizonte político de la religión
Authors: Guillermo Zapata, S, J 
Published: January 2020

La política y la religión siempre han estado estrechamente relacionadas en tanto que ambas dependen de la manera en la que el hombre se ve a sí mismo y al mundo que lo rodea. Pero una de las características principales de la democracia, el sistema político mayormente aceptado en el mundo de hoy, es su secularización. La democracia ya no permite tronos, y la religión ha sido reducida a una posibilidad de tantas que tienen los individuos al momento de elegir cómo quieren vivir sus vidas. No obstante, todo sistema político implica una religión diferente, y viceversa. La democracia no es de hecho el momento del fin de la religión, sino una reconfiguración absoluta de la experiencia religiosa que podría llegar a ser considerada la más auténtica de todas. El presente artículo investiga la mutua dependencia entre política y religión a partir de la cosmovisión que el hombre tiene de sí mismo en el contexto de la democracia asumiendo el desafío planteado a la libertad religiosa desde el horizonte político que se propone como tarea el camino de la paz
Ultrasound tissue characterization - to measure matrix integrity and to quantify regenerative processes in equine tendons and ligaments
Authors: Van Schie Hans 
Published: January 2020

Tendon injuries often threaten the athletic career of performance horses. There may be single overloading but frequently the injury is the result of a gradual matrix degradation, initially without clinical signs, which may lead to impaired regenerative capacity. Another complicating factor is the lack of uniform pathology; frequently multiple stages of matrix integrity can be found and, therefore, there is no cure-all treatment. Ultrasound Tissue Characterization (UTC) is designed for tomographic visualization and quantification of 3-D matrix integrity. UTC is based on standardized compilation of ultrasound-data by means of an ultrasound probe that moves automatically along the tendon’s long axis, collecting transverse images every 0.2 mm, generating a 3-D volume. UTC-algorithms can discriminate 4 different echo-types, related to size and integrity of structures in the matrix (van Schie et al. 2003):

Echo-type I, generated by intact and aligned fascicles with axial diameter ≥ spatial resolution.
Echo-type II, generated by discontinuous, waving and/or swollen fascicles with axial diameter ≥ spatial resolution.
Echo-type III, generated by a matrix mainly consisting of fibrils with axial diameter < spatial resolution.
Echo-type IV, generated by a mainly amorphous matrix and fluid.

Fundamental research with isolated tendons revealed that the ratios of these 4 echo-types are highly correlated with tendon matrix integrity, showing the discriminative power of UTC for tissue characterization (van Schie et al. 2009).Normal superficial digital flexor tendons in young mature horses are characterized by 80-90% type I, 10-15% type II and barely any type III and/or IV echoes. Loss of integrity is characterized by significant changes like decrease of type I, increase of type II (remodeling or inferior repair) and increase of type III (fibrillar) and/or IV (amorphous). Intra- and inter- observer reliability appeared to have intra-class correlations (ICC) ranging 0.92-0.98, indicative for excellent reproducibility. Clinical research revealed that UTC is sensitive and reliable to: • Monitor load-effects and detect matrix degradation (Plevin et al. 2019). Stage lesions for selection of appropriate intervention. • Quantify regenerative processes for objective evaluation of therapy and guided rehabilitation (Bosch et al. 2011).
The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica
Authors: Vindas Bolaños Rafael , Malda Jos , Van Weeren René , De Grauw Janny 
Published: January 2020

The paper provides results published or to be published of long-term in vivo equine studies to evaluate techniques of possible regenerative matrices of cartilage and bone, by means of cell-free implants or stimulation of the bone marrow. From the fixation techniques analyzed, it can be concluded that the best alternatives are the pressure technique for subchondral defects and a novel hydrogel with self-adhesive capacity for chondral defects. The equine coxal tuberosity was used for the first time as a model for regeneration studies of bone defects, analyzing scaffolds based on tricalcium phosphate, polymers and nanoparticles, by means of 3-D printing. Osteoconductivity, osteoinductivity, and the importance of microporosity were documented.Given that decellularized materials do not always give significant desired results in the regeneration of cartilage, it is important to conduct long-term studies. The technique of nanofracture and a novel self-adhesive hydrogel in the knee of the equine showed promising preliminary results in the regeneration of cartilage.The knee and the coxal tuberosity of the horse represent models of studying cartilage and bone regeneration in a true translational sense as a source of highly valuable information for clinical studies, for both horses and humans.
SOME BIOLOGICAL ASPECTS OF SKIPJACK TUNA (Katsuwonus pelamis LINNAEUS, 1758) DI PERAIRAN TOLI-TOLI WATERS, CENTRAL SULAWESI
Authors: Chodrijah Umi , Hidayat Thomas , Wagiyo Karsono 
Published: January 2020

Skipjack tuna (Katsuwonus pelamis) was one of the export commodities, where the demand tends to increase. The high level of skipjack tuna exploitation leads to overfishing, so sustainable fisheries management was required. The objective of the research was to study the several aspects of biology including of length of weight relationship, sex ratio maturity stage, gonad somatic index (GSI), Length at first capture and length at first maturity. The research was conducted in February - December 2015 in Toli-toli, Central Sulawesi. The results showed that the skipjack tuna growth pattern was allometrically positive, where growth weight was faster than the length increase. The length of the first time capture skipjack tuna of pole and line was bigger than length at first maturity, it means the mostly skipjack tuna caught have already spawned. The spawning season was occur throughout the year with spawning peaks in April and September, fecundity ranging from 450,570 - 1,707,390eggs.
Resistance of passive inclined anchors in cohesionless medium
Authors: Murray E. J. , Geddes J. D. 
Published: January 2020

The passive resistance of inclined anchor plates in sand is examined. Laboratory experimental results are presented for the ultimate passive resistance, and the corresponding displacements, of rectangular anchor plates pulled at angles of inclination between the vertical and the horizontal through very dense sand. The results of ultimate passive resistance are compared with theoretical solutions based on the upper and lower bound limit theorems of soil plasticity. A general lower bound solution for a strip anchor pulled at various angles of loading cannot be readily formulated, and only a poor lower bound solution for the case of horizontal loading is determined. However, it is shown that provided interface friction is taken into account, upper bound solutions for a strip anchor compare favourably with the experimental evidence. Good agreement is shown between the upper bound solutions and the equivalent free surface stress characteristic solution, and experimental data, of Neely et al. (1973) for the horizontal translation of anchor plates in medium dense sand. Comparison is also made between the experimental results of this Paper and the finite element approach of Rowe & Davis (1982) for anchors pulled horizontally through an assumed elastic-plastic soil. L'article examine la résistance passive des plaques d'ancrage inclinées. Les résultats de quelques expériences effectuées en laboratoire sont présentés concernant la résistance passive limite et les déplacements correspondants de plaques d'ancrage rectangulaires arrachées selon des directions comprises entre la verticale et l'horizontale à travers du sable de grande densité. Les résultats pour la résistance passive limite sont comparés avec des solutions théoretiques basées sur les valeurs supérieures et inférieures possibles des théories de la plasticité du sol. Il est difficile de formuler une solution générale pour les valeurs inférieures pour une plaque d'ancrage extraite à des angles différents tandis qu'on ne détermine qu'une solution peu satisfaisante pour les valeurs inférieures dans le cas du chargement horizontal. Nénamoins, à condition qu'on tienne compte du frottement d'interface, les solutions dans les valeurs supérieures s'accordent très bien avec les résultats expérimenteaux. On démontre un accod satisfaisant entre les solutions limites des valeurs supérieures et la solution equivalent basée sur les caractéristiques de contrainte superficielle libre et les données expérimentales de Neely et autres (1973) pour la translation horizontale des plaques d'ancrage dans du sable de densité moyenne. On compare aussi les résultats décrits dans cet article avec la méthode aux éléments finis de Rowe et Davis (1982) pour des ancrages horizontalement à travers un sol élastoplastique.
El léxico de la huerta en el Libro de agricultura de Alonso de Herrera
Authors: Sánchez Orense Marta 
Published: January 2020

El Libro de agricultura de Gabriel Alonso de Herrera es una obra más bien desconocida, y tanto en el ámbito científico en general como en el filológico y lexicográfico en particular, pese a ser un texto fundamental del Renacimiento español. Dicha circunstancia motiva la ejecución de un proyecto de investigación dedicado a elaborar una edición fidedigna de este volumen a partir de las seis primeras ediciones del texto, enmendadas por el propio autor, nacido en Talavera de la Reina. La exactitud y riqueza del vocabulario recopilado figuran entre los rasgos que han sido enfatizados por los pocos que sí han reparado en esta obra, de ahí que el objetivo del presente trabajo se centre en las particularidades terminológicas del tratado, sobre todo de la edición de 1539, si bien se han tenido igualmente en consideración las alternativas léxicas que subyacen en las cinco versiones previas.En concreto, de los seis libros que articulan este tratado de agricultura, nos centramos en el cuarto, que se dedica temáticamente al conocimiento de todo lo concerniente a las huertas, así como al cultivo de varias hortalizas y algunas hierbas, con sus características y propiedades, además de sus enfermedades comunes, aparte de las tareas agrícolas propias, como estercolar y regar. Tras la lectura y selección léxica de los treinta y siete capítulos que lo conforman, se ha realizado un análisis lexicológico de este vocabulario especializado, el cual constituye nuestra principal aportación.
Análisis terminológico del manual geométrico (Madrid, 1640) de Juan Carlos della Faille
Authors: Sánchez Martín Francisco Javier 
Published: January 2020

En el marco del corpus científico-técnico constituido para el proyecto de investigación enfocado al estudio de la lengua matemática española del siglo XVII,financiado por la Fundación Séneca, cabe destacar el manuscrito Método de la geometría(Madrid, 1640), fruto de la actividad científica y docente del matemático amberino Juan Carlos della Faille en el Colegio Imperial madrileño.  Si bien el tecnolecto matemático, en coincidencia con otros ámbitos de especialidad, presenta características morfológicas y sintácticas prototípicas, además de modelos textualesy discursivosespecíficos, sus particularidades lingüísticas residen primordialmente en el vocabulario técnico, ámbito preferente de atención en este trabajo. El análisis del plano léxico prestará atención a diferentes aspectos, tales como significados, transmisión y documentación. Para ello partimos de los datos y de la información que nos proporciona su autor para someterlos a análisis y compararlos con los que nos ofrecen otras fuentes (corpus en línea, obras históricas o diccionarios). Así, Juan Carlos della Faille declara en su obra la importancia de la claridad y la clasificación conceptuales, en paralelo con la destreza en el estudio de la perspectiva y su aplicación práctica en la delineación objetual, por ejemplo, al incluir el primer ejercicio enfocado a “bien aprehender todos los términos con sus difiniciones y declaraciones y no solamente imprimirse las figuras en la imajinación, sino también ejercitarse en dibujarlas con facilidad y perfección” (fol. 28v).Por otro lado, a partir de numerosos ejemplos, se pondrá de manifiesto que las imágenes han guiado, al lado de las palabras, nuestra comprensión; dicho apoyo visual permite, en ámbitos como el geométrico, descifrar la formulación de problemas planteados por los matemáticos.
Aproximación al léxico de tejidos en el Madrid del siglo XIX a partir de prensa local y documentación archivística
Authors: Vázquez Balonga Delfina 
Published: January 2020

El objetivo principal de este trabajo es profundizar sobre el léxico de los tejidos en el Madrid decimonónico a partir de una muestra de prensa local, el Diario de Avisos de Madrid (1825-1826). Sus anuncios de ventas de género textil recogen los nombres de telas más populares en el Madrid de la época: cotanza, percal, inglesina, levantina y alepín, entre otros. Una parte de estos nombres se encuentran por vez primera en textos del siglo XIX; en cambio, algunos de ellos no tienen registro lexicográfico. Para datar e identificar estos términos, consultamos fuentes textuales como el CORDE, pero también acudimos al corpus ALDICAM, en el que se encuentran documentos archivísticos inéditos, fechados en el siglo XIX y procedentes de dos instituciones benéficas madrileñas (Inclusa y Hermandad del Refugio). Estas piezas reflejan con fidelidad la lengua de uso en su tiempo, por lo que tiene gran interés para la comparación con los datos de los anuncios de la prensa coetánea.