bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tp-e interval and Tp-e/QTc ratio are significantly increased in patients with brain death
Authors: Demirtaş Abdullah Orhan 
Published: April 2020

Objective: We aimed to investigate whether there is a change in Tpe interval, Tpe/QT and Tpe/QTc ratios in patients with brain death.
Materials and Methods: Fifty brain death patients and 50 age and sex matched healthy controls were included in the study. In addition to routine evaluation, Tp-e interval, Tp-e / QT and Tp-e / QTc ratios were measured in 12-lead electrocardiography. Tp-e was measured in the precordial leads using the Tail method; the time from the peak of the T wave to the point where the wave reached the isoelectric line.
Results: White blood cell, aspartate aminotransferase, alanine aminotransferase and high sensitive c reactive protein levels were significantly higher in patients with brain death. The frequency of patients with QTc prolongation, Tp-e interval, Tp-e/QT and Tp-e/QTc values were significantly higher in patients with brain death (p <0.05). Tp-e interval, Tp-e/QT and Tp-e/QTc values were found to be positively correlated with HsCRP (p<0.001 for all). The cutoff value of Tpe/QT ratio obtained by ROC curve analysis was 0.225 for prediction of brain death (sensitivity: 64.0%, specificity: 84.0%). The area under the curve (AUC) was 0.824 (p<0.001).
Conclusion: Tp-e interval, Tp-e / QT and Tp-e / QTc ratios are increased in patients with brain death compared to healthy controls. This may be related to the effect of the changing neuroendocrine state in patients with brain death.
Pain Managment of Multiple Rib Fractures on the Basis of Early Reduction and Fixation in Patients without Intensive Care Unit.
Authors: Ağababaoğlu Ismail 
Published: April 2020

Objective: Blunt thoracic traumas are often complicated with rib fractures. The decision-making process of the treatment approaches not clear for clinicians. So, we aim to investigate the effect of surgical intervention on pain managment of patients as treatment indication.
Methods: Cases with 3 or more rib fractures were evaluated in our study. 84 patients underwent open reduction from 2014 to 2018 and 127 patients were treated conservatively from 2014 to 2018 included in the study. Surgery was performed for all cases in first 24-36 hours and no patient needed intensive care. The results of hospitalization time, pneumonia, rates, thoracic deformity rates on 6.month thorax computerized tomography, intercostal blockage requirement, postoperative 6.month quality of life questionnaire for pain and clinical outputs of two groups were retrospectively analyzed.
Results: The average hospitalization was found that it was significantly different in favor of the surgical group (z = 6.674; p <0.001). Thoracic deformity rates, intercostal blockage requirement was found to be different between the surgery and non-surgery groups (χ2=7.149;p<0.001), (χ2=22.462;p<0.001). Pain and quality of life scores had also significant difference in favor of the surgical group, respectively (z = 9.270; p <0.001) and (z = 8.796; p <0.001). Additionally there was statistical difference in pneumonia rates (p= 0.020). We did not reach a statistically significant result between the early and late groups in pain 1 and pain 2 results (p1: 0.727, p2: 0.069).
Conclusions: There is no consensus on rib fractures. The results of our study suggest that open rib reduction and fixation can be better treatment option than conservative approach in terms of pneumonia rates, hospitalization time, thoracic deformity rates and pain management.
The Difference in Clinical and Prognostic Features Between De Novo and Recurrent Her2-Positive Metastatic Breast Cancer Patients
Authors: Acikgoz Yusuf , Ergun Yakup , Ucar Gokhan , Dirikoc Merve , Uncu Dogan 
Published: April 2020

Abstract

BACKGROUND: There are different data in the literature about the consequences of the development of metastasis as de novo or recurrent. In this study, we retrospectively investigated the clinicopathologic and prognostic characteristics of HER-2 positive de novo and recurrent metastatic breast cancer (MBC) patients.
PATIENTS AND METHODS: The data of patients admitted to our clinic between 1996-2017 were analyzed retrospectively. The baseline features, treatments and survival data were recorded. Recurrent metastatic patients were further categorized as disease free interval (DFI) <24 months and DFI >24 months. The features of two groups were analyzed by pearson chi-square test. Survival were calculated by using the Kaplan-Meier method with the Long-rank test. p <0.05 was considered statistically significant.
RESULTS: A total of 44 patients were included to study in which 20 patients in de novo HER-2 positive MBC group and 24 patients in recurrent HER-2 MBC group. There was no difference in baseline features between groups. The median OS in de novo and recurrent MBC group was 60.3 months and 43.9 months respectively (HR: 0.87, 95% CI 0.37-2.05, p=0.76). OS was not different between de novo MBC group and patients with DFI <24 months and with DFI > 24 months (p=0.135).
CONCLUSION: Our study showed that baseline features of patients with de novo HER-2 positive MBC and recurrent HER-2 positive MBC did not differ from each other. The presence of metastasis at the time of diagnosis or during follow-up did not change response to treatments.
Efek Neuroprotektor Kunyit pada Pasien Alzheimer
Authors: Gemiralda Rika Mutiara , Marlaokta Marlaokta , Marlaokta Marlaokta 
Published: April 2020

Alzheimer merupakan penyakit neurogeneratif kronis progresif. Penyakit ini ditandai dengan gangguan fungsi luhur seperti bahasa, kalkulasi, kapasitas belajar dan sulit mengambil keputusan. ‘Pikun’ merupakan istilah yang digunakan masyarakat untuk menggambarkan penyakit ini. Kehilangan memori jangka pendek merupakan kekhasan dari penyakit ini yang menyebabkan penurunkan produktivitas. Alzheimer sering terjadi pada usia > 65 tahun dan juga ditemukan pada sekitar usia 40 tahun. Kunyit (Curcuma longa L.) merupakan tanaman yang berfungsi sebagai neuroprotektor karena dapat menghambat Protein Tau, akivitas asetilkolinesterase dan berfungsi sebagai anti agregasi Aβ dan β secretase inhibitor. Literature review ini bertujuan untuk menjelaskan gambaran efek neuroprotektor pada kunyit terhadap pasien Alzheimer yang sudah dilakukan oleh peneliti sebelumnya. Metode yang digunakan dalam artikel ini adalah penelusuran artikel melalui database NCBI dan Google Scholar. Tahun penerbitan sumber pustaka adalah dari tahun 2001 sampai 2019 dengan 32 sumber pustaka.Tema dalam artikel yang dikumpulkan yaitu terkait gambaran efek neuroprotektor kunyit terhadap pasien Alzheimer. Hasil dari sintesa artikel yang telah ditemukan yaitu kunyit dapat mencegah penurunan kognitif pada pasien Alzheimer. Kata kunci : Alzheimer, Kunyit, Neuroprotektor EFFECT OF NEUROPROTECTOR TURMERIC ON ALZHEIMER’S PATIENTS ABSTRACT Alzheimer's is a chronic progressive neurogenerative disease. This disease is characterized by impaired noble functions such as language, calculations, learning capacity and difficulty making decisions. ‘Pikun’ is a word used by the community to describe this disease. Short-term memory loss is a spesific sign in the patient, this disease causes decrease in productivity. Alzheimer's often occurs at age> 65 years and is also found at around the age of 40 years. Turmeric (Curcuma longa L.) is a plant that functions as a neuroprotector because it can inhibit Tau Proteins, acetylcholinesterase activity and function as anti-aggregation Aβ and β secretase inhibitors. This literature review aims to explain the description of the effects of neuroprotector on turmeric on Alzheimer's patients that have been done by previous researchers. The method used in this article is the search of articles through the NCBI and Google Scholar databases. The themes in the articles collected are related to the description of the effects of turmeric neuroprotector on Alzheimer's patients. The year of publication of library sources is from 2001 to 2019 with 32 library sources. The results of various articles included in this article are turmeric can prevent cognitive decline in Alzheimer's patients. Keywords: Alzheimer's,Turmeric, neuroprotector
Dukungan Keluarga Berhubungan dengan Harga Diri pada Penderita Tuberkulosis Paru
Authors: Suryani Ulfa , Efendi Zulham 
Published: April 2020

Tuberkulosis Paru menyebabkan dampak fisik dan psikologis, apabila tidak memiliki mekanisme koping dandukungan keluarga yang baik dapat menyebabkan gangguan pada harga dirinya.Tujuan dari penelitian ini untuk mengetahui hubungan dukungan keluarga dengan harga diri pada penderita Tuberkulosis Paru di Puskesmas Andalas Padang. Desain Penelitian yang digunakan adalah deskriptif korelasi dengan pendekatan secara cross sectional. Sampel penelitian diambil sebanyak 42 orang dengan cara total sampling. Pengumpulan data menggunakan kuesioner. Pada penelitian ini analisis data dilakukan secara univariat dan bivariate menggunakan uji Chi Square dengan p value = 0,05. Hasil penelitian diketahui bahwa lebih dari separoh penderita Tuberkulosis Paru mengalami harga diri rendah (61,9%) dengan dukungan keluarga yang kurang (54,8%). Dengan menggunakan uji korelasi, terdapat ada hubungan yang signifikan antara dukungan keluarga dengan harga diri penderita Tuberkulosis Paru (p value = 0,037) memilliki nilai hubungan positif dengan interpretasi cukup. Kata kunci: tuberkulosis paru, harga diri, dukungan keluarga FAMILY SUPPORTING RELATIONSHIPS WITH SELF-ESTEEM IN PATIENTS WITH PULMONARY TUBERCULOSIS ABSTRACTPulmonary Tuberculosis causes physical impact and psychological sufferers, if it does not have a coping mechanism and good family supporting so it can cause the disturbance in their pride. The purpose of this research is to know about family supporting relationships with self-esteem in patients of Pulmonary Tuberculosis in PuskesmasAndalas Padang. The design of research that used is the descriptive correlations with approaching in cross sectional. The sample of research is taken as many as 42 people with using total sampling. The collecting of data uses questionnaire. In this research the analyzing of data is done by Univariat and Bivariat that uses Chi Square test with p value = 0,05. The result of research is known that more than half of patients Pulmonary Tuberculosis experience low self-esteem (61,9%) with lack of family supporting (54,8%). In using correlation test there is the relationship which is significant between family supporting with self-esteem of Pulmonary Tuberculosis patients (p value = 0,037) that have a positive relationship value with enough interpretation Keywords: pulmonary tuberculosis, self-esteem, family supporting
Organizing Public Health Services Based on Best Practice Study of the "Layad Rawat" Innovation Program in Bandung
Authors: Adiguna Aditya Putera , Rahmawati Dian Eka 
Published: April 2020

Penelitian ini dilatarbelakangi oleh upaya Pemerintah Kota Bandung dalam memperbaiki kualitas pelayanan kesehatan yang selama ini dilakukan secara konvensional, yaitu warga harus mendatangi fasilitas kesehatan terlebih dahulu agar dilayani. Permasalahan sebuah kota khususnya Kota Bandung sudah berkembang sangat kompleks sehingga solusi-solusi konvensional seringkali tidak dapat untuk mengatasi permasalahan dalam pelayanan kesehatan, maka diperlukan solusi-solusi yang lebih inovatif untuk menyelesaikan permasalahan layanan kesehatan di Kota Bandung. Inovasi tersebut bernama Layad Rawat. Melalui program ini, Kota Bandung telah berupaya dalam meningkatkan pelayanan kesehatan dan memfasilitasi kebutuhan masyarakat. Teknik pengambilan data, dilakukan dengan cara wawancara mendalam (deep interview) kepada Dinas Kesehatan dan UPT P2KT Kota Bandung, dokumen tertulis berupa peraturan-peraturan resmi, arsip, dan dokumentasi gambar. Hasil penelitian menunjukan bahwa program Layad Rawat sesuai dengan kriteria best practice, dilihat dari dampak kemunculan Layad Rawat, terciptanya kemitraan dengan sektor swasta, peran kepala daerah yang sangat mendukung terhadap program, keadilan bagi semua warga untuk mengakses layanan, keberlanjutan, serta adopsi oleh daerah lain. Melalui Layad Rawat, masyarakat Kota Bandung tidak lagi mengalami kesulitan untuk mendapatkan akses pelayanan kesehatan, hanya memanggil Call Center 119. Praktik inovasi Layad Rawat dalam peningkatan kualitas pelayanan kesehatan di Kota Bandung merupakan solusi terbaik dalam menjawab permasalahan yang dirasakan masyarakat.
Kata Kunci: Inovasi, Pelayanan Kesehatan, Layad Rawat.
HUBUNGAN PEMANFAATAN DANA BANTAUAN OPERASIONAL KESEHATAN DENGAN CAKUPAN PROGRAM KESEHATAN IBU DI KABUPATEN KONAWE SELATAN
Authors: Tiku Sija , Supodo Timbul , Sunarsih  
Published: April 2020

Introduction: Health Operational Assistance (HOA) is the government program for financing the mandatory health effort which is include promotive and preventive health effort. However untill now the health programs that funded by BOK (HOA) especially maternal health program is not indicate the maksimum result or it is not achieve the target of Minimum Service Standdard that required to achieve the 100% targets. Every year the maternal mortality is excelsior, the coverage maternal health is decline.
Objective: This research is aimed to find out the relationship between the utilization of health opperational assistance funds and the coverage of the maternal health program namely the fourth antenatal health service (K4), Childbirth assistance by the health and childbirth labour in health facility in South Konawe regency based on HOA (BOK) fund allocations aspect and the implementation of mini clinic workshop.
Method: The kind of research is cross sectional study. Population in this research are the head of clinic, the HOA (BOK) fund’s organizer, the maternal health program’s organizer, coordinator midwife, the village’s midwife in 23 clinics in South Konawe regency. The population number in this research are 115 respondents. Sample in this research are 85 respondents from 17 clinics. Sample interpretation techniques in this research used Stratified Proportional Simple Random Sampling. Analysis data based on descriptive and inferential held with bivariate analysis by meas of chi square stage.
Result: Majority the respondent’s age around 26-30, educational level on stratum Diploma III. The research result indicates that there is no relationship between mini clinic workshop and coverage maternal health program, acquired value X2 arithmetic< X2 table (0,360<3,841). Existing meaningful relation between BOK (HOA) fund’s allocation and coverage maternal health program, value X2 arithmetic < X2 table (4,663 > 3,841). The result of closeness relation test indicates coefficient Phi(Φ) as big as 0,427, this case indicates the strength relation between BOK (HOA) fund’s allocation and coverage maternal health program in South Konawe regency.
Conclusion: interm rise the coverage maternal health program, the evaluatio of BOK (HOA) fund’s utilizing is necessary in clinic especially on fund’s allocation distribution for priority and evaluation of mini clinic workshop implementation.

Keywords :BOK (HOA) fund allocations, Coverage maternal health program, Mini clinic workshop.
PENGARUH SOCIAL LEISURE ACTIVITY TERHADAP PENURUNAN RISIKO WANDERING PADA LANSIA DEMENSIA DI RSJ Dr. RADJIMAN WEDIODININGRAT LAWANG MALANG
Authors: Kusumaningsih Amalia - , Yusuf Ahmad , Suhardiningsih AV Sri 
Published: April 2020

Introduction: Dementia is a clinical syndrome of decline in cognitive function. Dementia with various neuropsychiatric symptoms can have a large impact on both clients and caregivers, one of which is wandering behavior. Wandering is a neuropsychiatric symptom that is difficult to control, challenging, at risk of loss, causes various risks of fracture, and even death. Wandering management still uses traditional methods until now. The purpose of this study was to determine the effect of Social Leisure Activity in reducing the risk of wandering. Methods: The design of this study was quasi-experimental with a pre-post test one group. The study population was 47 elderly and a sample of 34 elderly dementia along with their caregivers who were outpatients at the Psychogeriatric Clinic of Dr. RSJ Radjiman Wediodiningrat Lawang. The sampling technique used purposive sampling method. The independent variable in this study was the Social Leisure Activity and the dependent variable was wandering risk. The instrument used Elopement Screening to assess the risk of wandering, the KATZ Independence Index, and the Caregiver Training questionnaire. The intervention was carried out at home by the caregiver in the form of a series of activities carried out for 4 weeks with a frequency of 3 times a week and 45 minutes per activity. The caregiver was given training as well as a demonstration of wandering and social leisure activity before the research was conducted. Data were analyzed using Paired-Samples T-Test. Results: The results of the analysis showed that there were significant differences (p = 0,000) on the value of the risk of wandering before and after an intervention. Training data on the caregiver gave a result that there was a significant difference (p = 0,000) in the caregiver's knowledge before and after training. Discussion: The risk of wandering in dementia elderly could be reduced by providing regular physical activities that prioritize elements of social interaction. Social Leisure Activity is an effective activity to be developed because it is easy to implement and efficient because it does not require high costs. Conclusions and Suggestions: Social Leisure Activities can help reduce the risk of wandering if done regularly and continuously. Social Leisure Activity can be used as an alternative for caregivers and elderly dementia to keep on doing activities.
STRESS PASIEN DENGAN ULKUS KAKI DIABETIKUM DI AL HIJRAH WOUND CARE CENTER JOMBANG
Authors: Kurdi Fahruddin , Kholis Anja Hesnia , Hidayah Nurul , Fitriasari Maya 
Published: April 2020

ABSTRACT
Diabetic foot ulcer is a complication of mellitus. The complication can cause psychological problems that cause stress for patient. The severity of diabetic foot ulcer will increase stress in patients. To deal with stress that needs to be overcome by reducing stress independently, besides the support system of the family is needed to help reduce stress and psychological burden. The purpose of this research is to explore how stress is experienced by diabetic foot ulcer patient.
This research is a qualitative research with phenomenology approach. Participants were diabetic ulcer who come for wound care treatments at Al Hijrah wound care center, as well as the nuclear family as additional informants. Data is taken with a thorough interview, observation.
The results obtained from two participants that stress due to diabetic ulcers is a condition related to physical and psychological conditions that cause participants to increase stress, such as: body image disorders, immobility, fear to amputation and cost difficulties.
The main effort to reduce stress is pray, read the Al Quran, dzikr and ask for help to health services in the hope that the stress can reduced independently and does not cause worse complications. It is hoped that further research will examine more deeply the stress experienced by patients with diabetic ulcers.
EDUKASI IBU MENYUSUI DENGAN ASI EKSKLUSIF MELALUI KOMUNIKASI INTERPERSONAL DI WILAYAH KERJA PAMULANG
Authors: Desmawati  , Agustina  , Kusumastuti Retno Dyah 
Published: April 2020

Permasalahan pada ibu-ibu menyusui (busui) setelah melahirkan adalah mengalami ketidaklancaran pengeluaran ASI; tidak adanya produksi ASI, produksi ASI (payudaranya) penuh, namun ejeksi ASI tidak lancar, puting susu yang kurang menonjol, dan lain-lain sehingga masih banyak bayi yang diberikan Pengganti Air Susu Ibu (PASI), padahal makanan yang terbaik untuk bayi adalah ASI. Salah satu penyebab hal tersebut terjadi karena kurangnya pengetahuan ibu dan keluarga. Pengetahuan ibu menyusui dan keluarganya terkait ASI eksklusif sangat penting untuk memaksimalkan pemberian ASI eksklusif pada bayi. Selain itu ibu menyusui harus terhindar dari stress, cemas, ketidaknyamanan, ketidaktenangan atau ibu harus selalu bahagia. Tujuan dari pengabdian ini adalah menambah pengetahuan, meningkatkan pemahaman dan perubahan perilaku busui, dan keluarga di lingkungan wilayah kerja Puskesmas Pamulang sehingga cakupan pemberian ASI eksklusif meningkat. Metode yang digunakan adalah health teaching dan demontstrasi pada 12 busui dengan komunikasi interpersonal di Pamulang pada tahun 2018. Hasil yang didapat setelah diberikan health teaching adalah pengetahuan mereka meningkat setelah diberikan Pendidikan kesehatan. Kesimpulan bahwa health teaching bisa meningkatkan pengetahuan ibu menyusui tentang ASI eksklusif. Disarankan health teaching segera dilakukan setelah melahirkan pada ibu menyusui walaupun semasa hamil sudah pernah diberikan.
Wdowieństwo a sytuacja materialna kobiet w starszym wieku w Polsce
Authors: Timoszuk Sylwia 
Published: April 2020

Widowhood of older women in Poland is an important research topic, especially for two reasons. First, widowed women constitute a relatively large subpopulation in the country. Second, the research conducted in other European countries showed that widowhood is related to a higher risk of poverty among women in older age groups. In the paper, I analyze the material situation of older widows in Poland and determine what factors are related to a higher risk of financial problems among them. In particular, I investigate a role of survivor’s pension for women’s material situation. I use data from the first wave of the Generations and Gender Survey, conducted in Poland (GGS-PL). The sample consists of widowed and married women aged 60–79, living in Poland. I apply the logistic regression analyses and use different measures of financial hardship. Regardless of which measure is used, the results showed that in comparison to marriage, widowhood is related to a higher risk of material deprivation among older women. Survivor’s pension does not mitigate this risk completely, but it is related to a significantly lower risk of a severe material deprivation.
Effects of Gibberellic Acid (Ga3) on Growth and Yield Parameters of French Bean (Phaseolus Vulgaris L.)
Authors: Noor Ferdowsi , Hossain Feroza , Ara Umme 
Published: April 2020

A field study was conducted during the Rabi season of 2009-2010 in the research field of Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka. Six levels of GA3, viz. 0, 30, 50, 70, 90 and 110 ppm were sprayed at 18 days after sowing (DAS). GA3 treatments significantly increased plant height than the control plants. GA3 with 30 to 90 ppm significantly increased number of branches and leaves, leaf area, leaf area index (LAI), leaf dry matter and total dry matter at different growth stages. GA3 at 30 to 70 ppm gradually increased crop growth rate (CGR), net assimilation rate (NAR) and relative growth rate (RGR) and declined advanced growth stages. Number of dry pods /plant, number of seeds /pod, 1000 seed weight, fresh fodder, fresh pod, dry seed yield and harvest index also significantly increased. Positive significant correlations were found among growth parameters and as well as yield contributing characters.
Asiat. Soc. Bangladesh, Sci. 43(1): 49-60, June 2017