bluuebunny/crossref_metadata_2025_split huggingface dataset:
KESULITAN BELAJAR MATEMATIKA: ANALISIS PENGETAHUAN AWAL [DIFFICULTY IN LEARNING MATHEMATICS: PRIOR KNOWLEDGE ANALYSIS]
Authors: Panggabean R. F. Setia Budi , Tamba Kimura Patar 
Published: December 2020

<p>In line with constructivism theory, prior knowledge is important in learning. Prior knowledge is the basis for a person being able to accept any new information that has been given. The background of this paper is the recognition that a number of students have difficulty learning mathematics. The results of observations when teaching grade 12 students about the matrix show that students still have difficulty in performing addition and subtraction arithmetic operations. This fact shows that there is a problem in students' prior knowledge. This paper aims to see the importance of the position of initial knowledge in student learning difficulties. This paper is a literature review. The results obtained show that initial knowledge is a source of student learning difficulties. This can be seen from the nature of mathematics and the thinking process of students in learning mathematics. From the nature of mathematics, according to constructivism, knowledge is acquired in a progressive constructive manner. Difficulties will arise when the prior knowledge is epistemologically different from the new knowledge. From the thinking process, students use their prior knowledge to construct new knowledge or respond to new information. The implication is that learning difficulties will arise when there is a conflict between prior knowledge and new knowledge.</p><p><strong>BAHASA INDONESIA ABSTRACT: </strong>Sejalan dengan teori konstruktivisme, pengetahuan awal (<em>prior knowledge</em>) merupakan hal penting dalam pembelajaran. Pengetahuan awal menjadi landasan bagi seseorang untuk mampu menerima informasi baru yang telah diberikan. Hal yang melatar belakangi tulisan ini adalah banyaknya anak didik yang kesulitan belajar matematika. Hasil observasi ketika mengajar SMA kelas XII tentang matriks menunjukkan siswa masih kesulitan dalam melakukan operasi hitung penjumlahan dan pengurangan. Hal tersebut menunjukkan ada masalah dalam pengetahuan awal siswa. Tujuan penulisan adalah untuk melihat pentingnya posisi pengetahuan awal dalam kesulitan belajar siswa. Tulisan ini merupakan kajian literatur. Hasil yang diperoleh menunjukkan pengetahuan awal merupakan sumber kesulitan belajar siswa. Hal ini dilihat dari natur matematika dan proses berpikir siswa dalam belajar matematika. Dari natur matematika, menurut teori konstruktivisme, pengetahuan diperoleh secara konstruktif progresif. Implikasinya, kesulitan akan muncul ketika secara epistemology pengetahuan awal berbeda dengan pengetahuan yang akan dipelajari. Dari proses berpikir, dalam membentuk pengetahuan baru atau merespon informasi yang dihadapkan padanya, siswa menggunakan pengetahuan awalnya. Implikasinya, kesulitan belajar akan muncul ketika terjadi konflik antara pengetahuan awal dengan pengetahuan yang akan dipelajari.</p><div><hr align="left" size="1" width="33%" /></div>
COMMUNICATION AND SELF-CONCEPT OF CHILDREN WITH DEAF AND SPEECH IMPAIRED
Authors: Mulyadi Eko , Oktavianisya Nelyta , Puspaningrum Ulva 
Published: December 2020

Introduction: The communication and interaction is the essence of every human as a social being. But, normal communications is not realyzed by the deaf speaking children. Deaf and speech impaired children affect self-concepts that affect communication. Where it will caused them to become inferior or have less confident. The confidence is begins through the formation of self-concept which formed from the experiences in their social interactions. This study aims to find the description of the communication and self-concept of the deaf and speech impaired children in SLB Darma Wanita Sumenep. Methods: This study used qualitative as a research methode with phenomenology approach. Respondents in this study are students of SLB Darma Wanita Sumenep who deaf and speech impaired start on birth. The sampling technique is used purposive sampling counted 10 respondents. The data collected by observation and in-depth interviews of respondents. The data were analyze with triagulation of the interview , key person, and observation. Results: Based on the results of this study, known that between the deaf speaking children and the normal people have problems in terms of understanding the symbols and sentences that there not regularly, so they often occur discommunication. The self-concept of deaf speaking children is tend to be shy with the opposite gender, less open with new people, but they have a high spirits for they futures. They need encouragement to socialize with new people and other normal people. It can make their self-concept and self-confidence can be better. Conclusion: The communication deaf and speech impaired children experience obstacles in sending or receiving messages due to interference in understanding the symbols and writing that are given.
Secondary Surgery and Residual Dysplasia Following Late Closed or Open Reduction of Developmental Dysplasia of the Hip
Authors: Morris William Z. , Hinds Sean , Worrall Hannah , Jo Chan-Hee , Kim Harry K.W. 
Published: December 2020

Background:
Outcomes studies following successful closed reduction of late-detected developmental dysplasia of the hip (DDH) reveal high rates of secondary reconstructive surgery with limited comparative data demonstrating lower rates of residual dysplasia with open reduction. The purpose of this study was to compare long-term outcomes, with regard to radiographic evidence of residual dysplasia and secondary reconstructive procedures, between late closed and late open reduction for DDH in patients 6 to 24 months of age at reduction.

Methods:
We identified all patients between 6 and 24 months of age who underwent closed or open reduction for DDH between 1980 and 2008 and were followed until at least 10 years of age. Outcomes included radiographic measurement of acetabular dysplasia after triradiate cartilage closure, development of osteonecrosis, and the need for secondary procedures for residual dysplasia.

Results:
One hundred and four hips underwent index closed reduction and 54 hips underwent index open reduction. There was no significant difference in the age at reduction (p = 0.07). Among the 116 hips for which initial anteroposterior pelvic radiographs were available, most closed reductions (55%) were performed in International Hip Dysplasia Institute (IHDI) grade-III hips whereas most open reductions (71%) were performed in IHDI grade-IV hips. Analysis of the hips that did not undergo a secondary procedure showed that those with an index open reduction had a greater lateral center-edge angle (mean and standard deviation, 27.2° ± 10.0° versus 22.4° ± 6.8° in the closed reduction cohort; p = 0.02), lower femoral head extrusion index (22.2% ± 8.9% versus 26.0% ± 6.2%; p = 0.04), and lower Sharp angle (43.3° ± 6.0° versus 46.6° ± 3.1°; p = 0.002) at triradiate closure. There was no difference in the prevalence of osteonecrosis (Bucholz-Ogden grades II, III, and IV) between the closed and open reduction cohorts (22% versus 19%, respectively; p = 0.60). Secondary procedures were performed more frequently after closed reduction than after open reduction (47% versus 30%, respectively; p = 0.03).

Conclusions:
In patients with late reduction of DDH, closed reduction was associated with increased residual dysplasia and it was associated with a higher rate of secondary surgery in those >12 months old despite a decreased severity of displacement based on the IHDI classification. Additional, prospective studies with assessment of functional outcomes are needed to validate these findings.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Hard-Soled Shoe Versus Short Leg Cast for a Fifth Metatarsal Base Avulsion Fracture
Authors: Choi Young Rak , Kim Bom Soo , Kim Yu Mi , Park Jae Yong , Cho Jae Ho , Kim Shinseok , Kim Hyong Nyun 
Published: December 2020

Background:
The purpose of this study was to determine whether tolerated weight-bearing in a hard-soled shoe was noninferior to the use of a short leg cast for the treatment of a fifth metatarsal base avulsion fracture, as assessed with use of a 100-mm visual analog scale (VAS) for pain at 6 months after the fracture.

Methods:
A total of 145 patients were assessed for eligibility. Of these, 96 patients were randomly assigned to either the hard-soled shoe group (46 patients) or the cast group (50 patients). The primary outcome measure was the mean difference on the 100-mm VAS between groups at 6 months after the fracture. Secondary outcome measures included the time to return to preinjury activity and patient-reported satisfaction. Analysis was performed according to both an intention-to-treat basis (i.e., patients were included in the assessment of their assigned treatment arm, even if they crossed over to the other treatment arm prior to completing the 6-month follow-up) and a per-protocol basis (i.e., patients who completed the 6-month follow-up were analyzed according to the treatment they received).

Results:
At 6 months after the fracture, the mean 100-mm VAS was 8.6 ± 7.0 mm in the hard-soled shoe group and 9.8 ± 7.3 mm in the cast group (p = 0.41) according to intention-to-treat analysis. The mean difference in 100-mm VAS between the 2 groups was −1.3 mm (95% confidence interval, −4.3 to 1.8 mm). The upper limit of the 95% confidence interval did not exceed the noninferiority margin of 10 mm, indicating that treatment with the hard-soled shoe was noninferior to treatment with the short leg cast. The proportion of patients who reported satisfaction with their treatment was similar between the hard-soled shoe and cast groups (89.5% compared with 87.5%, respectively; p = 0.79), but the time to return to preinjury activity was significantly shorter in the hard-soled shoe group (37.2 ± 14.4 days compared with 43.0 ± 11.1 days in the cast group; p = 0.04). There were no cases of nonunion in either group.

Conclusions:
Weight-bearing as tolerated in a hard-soled shoe for a fifth metatarsal base avulsion fracture was noninferior to the use of a short leg cast as assessed with use of a 100-mm VAS at 6 months after the fracture. Patient-reported satisfaction was similar between groups, but the time to return to preinjury activity was shorter in the hard-soled shoe group.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
The Use of Lockhart’s Memoirs (1714) in the Writings of Eighteenth-Century Whig Historians of the Anglo-Scottish Union (1707)
Authors: Deschamps Yannick 
Published: December 2020

Eighteenth-century whig historians of the Union (1707) reacted to Lockhart’s tory-jacobite Memoirs in different ways. While John Oldmixon (1672-1742) incorporated passages from them into his account of the Union for the sake of confuting them, Abel Boyer (1667-1729) and Nicholas Tindal (1687-1774) endorsed them to a large degree, borrowing from them extensively. Then, several historians writing in the mid- to late eighteenth century such as Thomas Somerville (1740-1830) or Malcolm Laing (1762-1818) approached them with an open mind, but also some critical distance, revealing an evolution in British historiography towards a more scholarly approach to historical sources.
Except for Oldmixon’s accounts, all those historians’s expositions of the Union were to some extent impacted by Lockhart’s Memoirs. Far from using the latter only as a storehouse of information on the Union, they were all in some mesure influenced by Lockhart’s vision of that event and, as a result, ideologically hybrid.
The Eureka Valley Landslide: Evidence of a Dual Failure Mechanism for a Long-Runout Landslide
Authors: Shaller Philip J. , Doroudian Macan , Hart Michael W. 
Published: December 2020

AbstractLong-runout landslides are well-known and notorious geologic hazards in many mountainous parts of the world. Commonly encompassing enormous volumes of debris, these rapid mass movements place populations at risk through both direct impacts and indirect hazards, such as downstream flooding. Despite their evident risks, the mechanics of these large-scale landslides remain both enigmatic and controversial. In this work, we illuminate the inner workings of one exceptionally well-exposed and well-preserved long-runout landslide of late Pleistocene age located in Eureka Valley, east-central California, Death Valley National Park. The landslide originated in the detachment of more than 5 million m3 of Cambrian bedrock from a rugged northwest-facing outcrop in the northern Last Chance Range. Its relatively compact scale, well-preserved morphology, varied lithologic composition, and strategic dissection by erosional processes render it an exceptional laboratory for the study of the long-runout phenomenon in a dry environment. The landslide in Eureka Valley resembles, in miniature, morphologically similar “Blackhawk-like” landslides on Earth, Mars, and minor planet Ceres, including the well-known but much larger Blackhawk landslide of southern California. Like these other landslides, the landslide in Eureka Valley consists of a lobate, distally raised main lobe bounded by raised lateral levees. Like other terrestrial examples, it is principally composed of pervasively fractured, clast-supported breccia. Based on the geologic characteristics of the landslide and its inferred kinematics, a two-part emplacement mechanism is advanced: (1) a clast-breakage mechanism (cataclasis) active in the bedrock canyon areas and (2) sliding on a substrate of saturated sediments encountered and liquefied by the main lobe of the landslide as it exited the main source canyon. Mechanisms previously hypothesized to explain the high-speed runout and morphology of the landslide and its Blackhawk-like analogs are demonstrably inconsistent with the geology, geomorphology, and mineralogy of the subject deposit and its depositional environment.
Magnetic Resonance Imaging in Assessment of Patients with Ketamine-Associated Cystitis
Authors: Chen Bo-Han , Yang Ming-Hsin , Kao Chien-Chang , Tsao Chih-Wei , Wu Sheng-Tang , Cha Tai-Lung , Sun Guang-Huan , Yu Dah-Shyong , Meng En 
Published: December 2020

Abstract
Background: Ketamine-associated cystitis (KC) is a new entity of disease. Our aim is to compare the magnetic resonance imaging (MRI) appearances of urinary bladder in recreational ketamine users with lower urinary tract symptoms (LUTS) and healthy subjects. Materials and Methods: MRI of pelvis was performed for 10 consecutive ketamine abusers with KC and 16 healthy young adults at a medical center in the northern Taiwan from January to December, 2011. The thickness of the bladder wall was measured and analyzed. All patients with KC had been diagnosed based on their history, clinical features and urodynamic study. Results: The mean bladder wall thickness of KC patients was significantly thicker than the control group (1.45±0.23 cm vs. 0.62 ± 0.50 cm, p < 0.001). There is significant positive correlation between the duration of ketamine usage and the thickness of bladder wall (r = 0.891, p =0.001); whereas the dosage of ketamine had weak positive correlation with the thickness of bladder wall (r = 0.413, p =0.235). Furthermore, the thickness of bladder wall was also strong correlated with maximum urethral closure pressure (MUCP; r = 0.855, p =0.002). Conclusions: Ketamine-associated cystitis causes increased bladder wall thickness which may be related to the bladder outlet obstruction. MRI is a useful tool to evaluate the bladder wall thickness and contributes to the diagnosis of ketamine associated cystitis.
Viral Hepatitis-HIV Co-Infection and their associated factors in Negeri Sembilan - a cross sectional study from HIV Case Registry
Authors: Abas Siti Aishah , Jamil Ahmad Taufik , Saman Mohd Shahril Ahmad , Mohammad Mariam , Ahmad Sharifah Nor 
Published: December 2020

Abstract
Background: Viral Hepatitis HIV Co-infection is an important and preventable cause of chronic liver disease, and having them lead to many consequences, especially for those living in wrenched conditions. Thus it is a significant health issue in the communities. This study aimed to determine the prevalence of Viral Hepatitis-HIV Co-Infection and determine the associated variables with this Co-Infection. Methods: A cross-sectional study was done using HIV Case Registry ( Anti Retroviral -(ARV) line listing). We included 1274 patients who were seen under the HIV Clinic services, which were screened for Hepatitis B Virus (HBV) and Hepatitis C Virus ( HCV) upon registered to the clinic. Factors associated with the HBV-HIV and HCV-HIV were determined using bivariate, and multivariate logistic regression analysis using SPSS and odds ratio was used as the measures of association. A P-value of less than 0.05 was considered statistically significant for all the tests. Results: From the 1274 number of HIV patients, the prevalence of HBV-HIV is 5.6% (71 cases), while the prevalence with HCV co-infection was 14.8% (189 cases). As for the frequency of multiple HIV-Coinfection, out of 238 HIV cases with Co-Infection, the majority of 167 cases (70.17%) were HCV-HIV Co-Infected followed by 49 cases (20.5%) were HBV-HIV Co-Infected. In comparison, another 22 cases ( 9.24%) were Co-Infected with HBV-HCV-HIV. In the final model of HBV-HIV Co-Infection, only male gender, CD4 count category less than 199 cells/mm3 and primary care type of facilities were associated with the disease whereas, in the HCV-HIV Coinfection, only male gender, Malay race, Intravenous Drug User (IVDU) modes of transmission, and source of the case from high-risk screening program were associated with the disease. Conclusions: Co-Infection with HCV-HIV is more prevalent from HBV-HIV in our study population. A more targeted intervention of HBV revaccination and more frequent screening of HCV post HCV treatment as reinfection is anticipated in high-risk behaviour patient are some of the intervention programs that can be suggested.
The Build-Up of Aerosols Carrying the SARS-CoV-2 Coronavirus, in Poorly Ventilated, Confined Spaces
Authors: Birnir Bjorn , Angheluta Luiza 
Published: December 2020

Abstract
A model of the distribution of respiratory droplets and aerosols by Lagrangian turbulent air-flow is developed and used to show how the SARS-CoV-2 Coronavirus can be dispersed by the breathing of an infected person. It is shown that the concentration of viruses in the exhaled cloud can increase to infectious levels with time (grow linearly), in a confined space where the air re-circulates. The model is used to analyze the air-flow and SARS-CoV-2 Coronavirus build-up in a restaurant in Guangzhou, China [23, 21]. It is concluded that the outbreak of Covid-19 pandemic in the restaurant in January 2020, is due to the build-up of the airborne droplets and aerosols carrying the SARS-CoV-2 Coronavirus and would not have been pre- vented by standard ventilation. A comparison with standard models for aerosol concentration shows that, in the absence of ventilation, the decay of the aerosol concentration is also con- trolled by the decay time of the virions in aerosols. This decay time is very long and a steady state is not achieved in the time-frame of the contagion. Instead the concentration exhibits a polynomial increase and reaches infectious levels in a relatively short time, explaining the outbreak in the restaurant in Guangzhou.
WITHDRAWN: Survival Nomograms for Patients with Pancreatic Neuroendocrine Tumors: A Population-based Study
Authors: Lin Bi , Yu Dinglai , Chen Shengchuan , Wang Daojie , Huang Chaohao 
Published: December 2020

Abstract
Background: Although pancreatic neuroendocrine tumors (PNETs) are considered indolent tumors, most patients are diagnosed at an advanced stage. We aimed to establish a nomogram for clinical use to predict the survival of PNET patients using the Surveillance, Epidemiology, and End Results (SEER) database.Methods: Based on the SEER database, 1,103 patients with PNETs were enrolled and randomly divided into training and validation sets. We performed Kaplan-Meier analysis and Cox proportional hazard regression analysis in the training set to evaluate the value of the prognostic factors. A nomogram was then constructed to analyze these independent prognostic factors for predicting the overall survival (OS) and specific cancer survival (CSS). C-index, calibration curve, and decision curve analysis were used to evaluate the predictive accuracy of the nomogram.Results: Age, primary site, TNM stage, grade, and surgery were associated with OS and CSS in the multivariate models. Nomograms were established depending on these risk factors and had a better discrimination power than the TMN stage. The validation techniques showed that the nomograms were able to predict the 3- and 5-year OS and CSS accurately, and also proved to be superior.Conclusions: Nomograms were established depending on these risk factors and had a better discrimination power than the TMN stage. The validation techniques showed that the nomograms were able to predict 3- and 5-year OS and CSS accurately, and also proved to be superior.
The Chromatin Remodeler Mi2/CHD4 is Required in Skeletal Muscle Stem Cells for Normal Muscle Development and Regeneration
Authors: Derfoul Assia , Pinal-Fernandez Iago , Huang Wilson , Parks Cassie , Pak Katherine , Hoffmann Victoria , Mammen Andrew , Georgopoulos Katia 
Published: December 2020

Abstract
The chromodomain helicase and DNA binding 4 (CHD4) protein is upregulated in regenerating myofibers. To define the role of CHD4 in muscle differentiation and regeneration, we generated mice with CHD4 ablated in muscle satellite cells (SCs). Embryonic day 18.5 CHD4 KO mice are non-viable, with atrophic intercostal and back muscles and altered expression of muscle contraction genes. Tamoxifen-inducible conditional CHD4 KO in adult mouse SCs diminished myoblast proliferation, induced premature differentiation, and altered expression of muscle contraction genes at the myotube stage. Following cardiotoxin–induced muscle injury, CHD4 KO regenerating myofibers had reduced cross-sectional area. ChIP-Seq analysis revealed that CHD4 binds actin a1, Wnt and b-catenin genes, which are known to play roles in the regulation of myogenesis. Together, our results suggest an important role for CHD4 in the control of embryonic myogenesis, SC differentiation, and the control of muscle fiber size in adult skeletal muscle during regeneration.