bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal reactions involving solids: a personal view of selected features of decompositions, thermal analysis and heterogeneous catalysis
Authors: Galwey Andrew K. 
Published: March 2020

AbstractConvinced that some recent trends in the literature concerned with reactions involving solids have been unproductive, even discouraging interest in the subject, this reviewer analyses the reasons and charts a way forward. In particular, two topics are discussed: thermal analysis and activation energy. Thermal analysis, automated collection and interpretation of kinetic data for solid(?)-state decompositions, resulted in huge numbers of publications between late 1970s and 2010. Measurements were frequently minimalistic (few, often no, confirmatory tests complemented rate data). Kinetic data interpretations were based on the Arrhenius activation model, inapplicable to these assumed, usually unconfirmed, solid-state(?) reactions. Energy distributions within crystalline reactants differ from those of ‘free-flying’ gaseous reactants, and thus, mechanistic proposals are entirely speculative. Such studies yielded little more than the reaction temperature: no meaningful insights into reaction chemistry, controls, mechanisms. Despite my several highly critical articles, these inconsequential studies continued. Overall, this now sidelined topic impacted adversely on solid-state chemistry, activation energy,E. Concurrently with the above studies, L'vov published a theoretical explanation for the magnitude ofE: the Congruent Dissociative Volatilisation (CDV), thermochemical approach. This was also ignored by the ‘Thermoanalytical Community’, possibly because it assumes an initial volatilisation step: it appears that many solid-state scientists are prejudiced against mechanisms involving a phase change. The value of this novel theory (CDV) in identifying controls and mechanisms of solid-state reactions is discussed here. This review is positive: an interesting branch of main-stream chemistry remains open for exploration, expansion, explanation and exploitation!
Knowledge of Maltese singular–plural mappings
Authors: Nieder Jessica , van de Vijver Ruben , Mitterer Holger 
Published: March 2020

AbstractWhich factors determine the choice of a plural allomorph for a new singular form? Are regular mappings stored differently from irregular mappings? Do native speakers only rely on analogical mappings to inflect novel word forms or do they use rules? To answer these questions we used data from Maltese, a language with a split morphology, which has a rich and variable set of concatenative and non-concatenative plural patterns.We conducted a production experiment, in which we investigated the mapping of a singular onto a plural. We show that this is driven by an interplay between the similarity of novel singular forms with existing singular words and their corresponding plural forms. Moreover, knowledge of the frequency of the plural patterns in the mental lexicon serves as a basis for generalization to novel words. Our results support an analogical model of morphological processing. We do not find evidence that native speakers use default rules.
Conceptualization and preliminary study of engineering disturbed rock dynamics
Authors: Xie Heping , Zhu Jianbo , Zhou Tao , Zhang Kai , Zhou Changtai 
Published: March 2020

AbstractMany large engineering projects, e.g., the Sichuan–Tibet Railway, inevitably cross the earthquake active areas and the geology complicated zones, facing the challenges of dynamic disturbances and disasters. In view of this, the conceptualization of engineering disturbed rock dynamics is proposed in this paper, aiming to systematically study the rock dynamic behavior and response subjected to engineering disturbances, to establish the 3D rock dynamic theory, and to develop the disaster prevention and control technical measures. The classification standards of rock loading states based on strain rate are summarized and analyzed. The engineering disturbed rock dynamics is defined as the theoretical and applied science of rock dynamic behaviors, dynamic responses and their superposition caused by dynamic disturbances during engineering construction and operation periods. To achieve the goals of the proposed engineering disturbed rock dynamics, a combined methodology of theoretical analysis, laboratory experiment, numerical simulation and in situ tests is put forward. The associated research scopes are introduced, i.e., experimental and theoretical study of engineering disturbed rock dynamics, wave propagation, attenuation and superposition in rock masses, rock dynamic response of different loading conditions, dynamic response of engineering projects under construction disturbance and disaster mitigation techniques, and dynamic response of major engineering projects under operation disturbance and safety guarantee measures. Some theoretical, experimental and field preliminary studies were performed, including dynamic behavior of disturbed rock at varied depth and strain rates, dynamic response of rock mass subjected to blasting excavation disturbance and dynamic drilling disturbance, and disturbance of rock mass subjected to TBM excavation. Preliminary results showed that the rock masses are significantly disturbed by dynamic disturbances during construction and operation periods of engineering projects. The innovative conceptualization of engineering disturbed rock dynamics and the expected associated outcomes could facilitate establishing the 3D rock dynamic theory and offering theoretical fundamentals and technical guarantees for safety and reliability of the design, construction and operation of modern large engineering.
A Novel Steganography Approach for Audio Files
Authors: Abdulrazzaq Sazeen T. , Siddeq Mohammed M. , Rodrigues Marcos A. 
Published: March 2020

AbstractWe present a novel robust and secure steganography technique to hide images into audio files aiming at increasing the carrier medium capacity. The audio files are in the standard WAV format, which is based on the LSB algorithm, while images are compressed by the GMPR technique which is based on the Discrete Cosine Transform and high-frequency minimization encoding algorithm. The method involves compression–encryption of an image file by the GMPR technique followed by hiding it into audio data by appropriate bit substitution. The maximum number of bits without significant effect on audio signal for LSB audio steganography is 6 LSBs. The encrypted image bits are hidden into variable and multiple LSB layers in the proposed method. Experimental results from observed listening tests show that there is no significant difference between the stego-audio reconstructed from the novel technique and the original signal. A performance evaluation has been carried out according to quality measurement criteria of signal-to-noise ratio and peak signal-to-noise ratio.
Manipulation Arguments and Libertarian Accounts of Free Will
Authors: CYR TAYLOR W. 
Published: March 2020

AbstractIn response to the increasingly popular manipulation argument against compatibilism, some have argued that libertarian accounts of free will are vulnerable to parallel manipulation arguments, and thus manipulation is not uniquely problematic for compatibilists. The main aim of this article is to give this point a more detailed development than it has previously received. Prior attempts to make this point have targeted particular libertarian accounts but cannot be generalized. By contrast, I provide an appropriately modified manipulation that targets all libertarian accounts of freedom and responsibility—an especially tricky task given that libertarian accounts are a motley set. I conclude that if manipulation arguments reveal any theoretical cost then it is one borne by all accounts according to which we are free and responsible, not by compatibilism in particular.
What Phenomenal Contrast for Bodily Ownership?
Authors: DE VIGNEMONT FRÉDÉRIQUE 
Published: March 2020

AbstractIn a 1962 article, ‘On Sensations of Position’, G. E. M. Anscombe claimed that we do not feel our legs crossed; we simply know that they are that way. What about the sense of bodily ownership? Do we directly know that this body is our own, or do we know it because we feel this body that way? One may claim, for instance, that we are we aware that this is our own body thanks to our bodily experiences that ascribe the property of myness to the body that they represent. Here I approach this issue from the perspective of the debate on the admissible content of perception, appealing to the method of phenomenal contrast. After rejecting the myness hypothesis, I criticize alternative accounts of the contrast in somatosensory, cognitive, and agentive terms. I conclude that the phenomenology of ownership consists in the affective awareness of the unique significance of the body for survival.
COVID-19 Epidemic in the Middle Province of Northern Italy: Impact, Logistics, and Strategy in the First Line Hospital
Authors: Gagliano Annalisa , Villani Pier Giorgio , Co’ Francesca M , Manelli Anna , Paglia Stefano , Bisagni Pietro A. G. , Perotti Gabriele M , Storti Enrico , Lombardo Massimo 
Published: March 2020

ABSTRACTThe novel coronavirus (COVID-19) began in China in early December 2019 and rapidly has spread to many countries around the globe, with the number of confirmed cases increasing every day. An epidemic has been recorded since February 20 in a middle province in Northern Italy (Lodi province, in the low Po Valley). The first line hospital had to redesign its logistical and departmental structure to respond to the influx of COVID-19-positive patients who needed hospitalization. Logistical and structural strategies were guided by the crisis unit, managing in 8 days from the beginning of the epidemic to prepare the hospital to be ready to welcome more than 200 COVID-19-positive patients with different ventilatory requirements, keeping clean emergency access lines, and restoring surgical interventions and deferred urgent, routine activity.
Basic Law: Israel as the Nation State of the Jewish People
Authors: Harel Alon 
Published: March 2020

AbstractBasic Law: Israel as the Nation State of the Jewish People declares that Israel is the nation state of the Jewish people. It also includes several symbolic and operative provisions which are designed to strengthen the Jewish character of the state. The Basic Law purports to legally define and entrench the particular rather than universal values of Israel—the values that distinguish Israel from other nations rather than those that are shared by other nations. It anchors the Jewish identity of the state in its formal constitutional structure. My aim in this article is to present the history of the constitutional evolution of Israel and then to describe the conservative reactions to the constitutional liberalization of Israel. Then, I turn to examine the Basic Law, its provisions, and the arguments of advocates and opponents. Last, I evaluate its impact on the Israeli legal system. I shall argue that the Basic Law is part of a systematic attack on democratic liberties in Israel that may eventually transform Israel from a liberal democracy to an authoritarian democracy.
Buprenorphine: prospective novel therapy for depression and PTSD
Authors: Madison Caitlin A. , Eitan Shoshana 
Published: March 2020

AbstractBackgroundDepression and post-traumatic stress disorder (PTSD) are leading causes of disability and loss of life by suicide. Currently, there are less than satisfactory medical solutions to treat these mental disorders. Here, we explore recent preclinical and clinical studies demonstrating the potential of using buprenorphine to treat major depressive disorder, treatment-resistant depression, and PTSD.MethodBibliographic databases were searched to include preclinical and clinical studies demonstrating the therapeutic potential of buprenorphine and the involvement of the kappa opioid receptor (KOR) in mediating these effects.ResultsOriginal clinical studies examining the effectiveness of buprenorphine to treat depression were mixed. The majority of participants in the PTSD studies were males and suffer from chronic pain and/or substance use disorders. Nonetheless, these recent studies and analyses established proof of concept warranting farther investigations. Additionally, KOR likely mediates the antidepressant and some of the anxiolytic effects of buprenorphine. Still, it appears that the full spectrum of buprenorphine's beneficial effects might be due to activity at other opioid receptors as well.ConclusionsPharmaceuticals' abilities to treat medical conditions directly relates to their ability to act upon the endogenous biological systems related to the conditions. Thus, these recent findings are likely a reflection of the central role that the endogenous opioid system has in these mental illnesses. Further studies are necessary to study the involvement of endogenous opioid systems, and specifically KOR, in mediating buprenorphine's beneficial effects and the ability to treat these medical conditions while minimizing risks for misuse and diversion.
Treatment selection in borderline personality disorder between dialectical behavior therapy and psychodynamic psychiatric management
Authors: Keefe John R. , Kim Thomas T. , DeRubeis Robert J. , Streiner David L. , Links Paul S. , McMain Shelley F. 
Published: March 2020

AbstractBackgroundNo evidence-based therapy for borderline personality disorder (BPD) exhibits a clear superiority. However, BPD is highly heterogeneous, and different patients may specifically benefit from the interventions of a particular treatment.MethodsFrom a randomized trial comparing a year of dialectical behavior therapy (DBT) to general psychiatric management (GPM) for BPD, long-term (2-year-post) outcome data and patient baseline variables (n = 156) were used to examine individual and combined patient-level moderators of differential treatment response. A two-step bootstrapped and partially cross-validated moderator identification process was employed for 20 baseline variables. For identified moderators, 10-fold bootstrapped cross-validated models estimated response to each therapy, and long-term outcomes were compared for patients randomized to their model-predicted optimal v. non-optimal treatment.ResultsSignificant moderators surviving the two-step process included psychiatric symptom severity, BPD impulsivity symptoms (both GPM > DBT), dependent personality traits, childhood emotional abuse, and social adjustment (all DBT > GPM). Patients randomized to their model-predicted optimal treatment had significantly better long-term outcomes (d = 0.36, p = 0.028), especially if the model had a relatively stronger (top 60%) prediction for that patient (d = 0.61, p = 0.004). Among patients with a stronger prediction, this advantage held even when applying a conservative statistical check (d = 0.46, p = 0.043).ConclusionsPatient characteristics influence the degree to which they respond to two treatments for BPD. Combining information from multiple moderators may help inform providers and patients as to which treatment is the most likely to lead to long-term symptom relief. Further research on personalized medicine in BPD is needed.
No action without talk? UN peacekeeping, discourse, and institutional self-legitimation
Authors: von Billerbeck Sarah 
Published: March 2020

AbstractIn this article, I argue that much of the discourse observable within the UN constitutes neither unnecessary and unproductive ‘talk’ nor efforts to convince outside audiences of its legitimacy, but actually a form of institutional self-legitimation that is key to its ability to function. Using the case of the UN's Department of Peacekeeping Operations (DPKO), I show that because the organisation has a multifaceted organisational identity, it faces situations where it is forced to choose between multiple but equally appropriate courses of action, and it uses self-legitimation alongside other mechanisms to overcome these tensions. I specify three sets of circumstances in which this occurs, showing how DPKO uses discourse that simplifies and exceptionalises in a bid to reconcile or downplay these contradictions and reassert a cohesive and legitimate organisational identity internally. This simplification and exceptionalisation in turn serve an enabling function, allowing DPKO to continue operating in conditions of complexity by decreasing risk aversion and instilling a deep sense of professional loyalty in staff. At the same time, such discursive processes are costly and may entrench inefficient practices, rendering the effects of self-legitimising discourse paradoxical: they may enable action, but they reduce the efficiency and effectiveness of that action.
Life, Death, Inertia, Change: The Hidden Lives of International Organizations
Authors: Gray Julia 
Published: March 2020

AbstractThe life spans of international organizations (IOs) can take unexpected turns. But when we reduce IO life spans simply to their existence or lack thereof, or to formal change involving the addition of new members or the revision of charters, we miss the subtler dynamics within IOs. A broader continuum of IO life spans acknowledges life, death, inertia, and change as responses to crises, and affords a more nuanced perspective on international cooperation. Through this lens, the setbacks that many IOs are currently experiencing look less extraordinary.
Identifying a human signal in the North Atlantic warming hole
Authors: Chemke Rei , Zanna Laure , Polvani Lorenzo M. 
Published: March 2020

AbstractNorth Atlantic sea surface temperatures have large climate impacts affecting the weather of the Northern Hemisphere. In addition to a substantial warming over much of the North Atlantic, caused by increasing greenhouse gases over the 21st century, climate projections show a surprising region of considerable future cooling at midlatitudes, referred to as the North Atlantic warming hole. A similar pattern of surface temperature trends has been observed in recent decades, but it remains unclear whether this pattern is of anthropogenic origin or a simple manifestation of internal climate variability. Here, analyzing state-of-the-art climate models and observations, we show that the recent North Atlantic warming hole is of anthropogenic origin. Our analysis reveals that the anthropogenic signal has only recently emerged from the internal climate variability, and can be attributed to greenhouse gas emissions. We further show that a declining northward oceanic heat flux in recent decades, which is linked to this surface temperature pattern, is also of anthropogenic origin.
Autophagy lipidation machinery regulates axonal microtubule dynamics but is dispensable for survival of mammalian neurons
Authors: Negrete-Hurtado A. , Overhoff M. , Bera S. , De Bruyckere E. , Schätzmüller K. , Kye M. J. , Qin C. , Lammers M. , Kondylis V. , Neundorf I. , Kononenko N. L. 
Published: March 2020

AbstractNeurons maintain axonal homeostasis via employing a unique organization of the microtubule (MT) cytoskeleton, which supports axonal morphology and provides tracks for intracellular transport. Abnormal MT-based trafficking hallmarks the pathology of neurodegenerative diseases, but the exact mechanism regulating MT dynamics in axons remains enigmatic. Here we report on a regulation of MT dynamics by AuTophaGy(ATG)-related proteins, which previously have been linked to the autophagy pathway. We find that ATG proteins required for LC3 lipid conjugation are dispensable for survival of excitatory neurons and instead regulate MT stability via controlling the abundance of the MT-binding protein CLASP2. This function of ATGs is independent of their role in autophagy and requires the active zone protein ELKS1. Our results highlight a non-canonical role of ATG proteins in neurons and suggest that pharmacological activation of autophagy may not only promote the degradation of cytoplasmic material, but also impair axonal integrity via altering MT stability.
Polychromatic solar energy conversion in pigment-protein chimeras that unite the two kingdoms of (bacterio)chlorophyll-based photosynthesis
Authors: Liu Juntai , Friebe Vincent M. , Frese Raoul N. , Jones Michael R. 
Published: March 2020

AbstractNatural photosynthesis can be divided between the chlorophyll-containing plants, algae and cyanobacteria that make up the oxygenic phototrophs and a diversity of bacteriochlorophyll-containing bacteria that make up the anoxygenic phototrophs. Photosynthetic light harvesting and reaction centre proteins from both kingdoms have been exploited for solar energy conversion, solar fuel synthesis and sensing technologies, but the energy harvesting abilities of these devices are limited by each protein’s individual palette of pigments. In this work we demonstrate a range of genetically-encoded, self-assembling photosystems in which recombinant plant light harvesting complexes are covalently locked with reaction centres from a purple photosynthetic bacterium, producing macromolecular chimeras that display mechanisms of polychromatic solar energy harvesting and conversion. Our findings illustrate the power of a synthetic biology approach in which bottom-up construction of photosystems using naturally diverse but mechanistically complementary components can be achieved in a predictable fashion through the encoding of adaptable, plug-and-play covalent interfaces.
Introducing the crystalline phase of dicalcium phosphate monohydrate
Authors: Lu Bing-Qiang , Willhammar Tom , Sun Ben-Ben , Hedin Niklas , Gale Julian D. , Gebauer Denis 
Published: March 2020

AbstractCalcium orthophosphates (CaPs) are important in geology, biomineralization, animal metabolism and biomedicine, and constitute a structurally and chemically diverse class of minerals. In the case of dicalcium phosphates, ever since brushite (CaHPO4·2H2O, dicalcium phosphate dihydrate, DCPD) and monetite (CaHPO4, dicalcium phosphate, DCP) were first described in 19th century, the form with intermediary chemical formula CaHPO4·H2O (dicalcium phosphate monohydrate, DCPM) has remained elusive. Here, we report the synthesis and crystal structure determination of DCPM. This form of CaP is found to crystallize from amorphous calcium hydrogen phosphate (ACHP) in water-poor environments. The crystal structure of DCPM is determined to show a layered structure with a monoclinic symmetry. DCPM is metastable in water, but can be stabilized by organics, and has a higher alkalinity than DCP and DCPD. This study serves as an inspiration for the future exploration of DCPM’s potential role in biomineralization, or biomedical applications.
Ultraviolet photolysis of H2S and its implications for SH radical production in the interstellar medium
Authors: Zhou Jiami , Zhao Yarui , Hansen Christopher S. , Yang Jiayue , Chang Yao , Yu Yong , Cheng Gongkui , Chen Zhichao , He Zhigang , Yu Shengrui , Ding Hongbin , Zhang Weiqing , Wu Guorong , Dai Dongxu , Western Colin M. , Ashfold Michael N. R. , Yuan Kaijun , Yang Xueming 
Published: March 2020

AbstractHydrogen sulfide radicals in the ground state, SH(X), and hydrogen disulfide molecules, H2S, are both detected in the interstellar medium, but the returned SH(X)/H2S abundance ratios imply a depletion of the former relative to that predicted by current models (which assume that photon absorption by H2S at energies below the ionization limit results in H + SH photoproducts). Here we report that translational spectroscopy measurements of the H atoms and S(1D) atoms formed by photolysis of jet-cooled H2S molecules at many wavelengths in the range 122 ≤ λ ≤155 nm offer a rationale for this apparent depletion; the quantum yield for forming SH(X) products, Γ, decreases from unity (at the longest excitation wavelengths) to zero at short wavelengths. Convoluting the wavelength dependences of Γ, the H2S parent absorption and the interstellar radiation field implies that only ~26% of photoexcitation events result in SH(X) products. The findings suggest a need to revise the relevant astrochemical models.