bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prestroke statin use enhances collateralization in acute ischemic stroke patients
Authors: Zhu Jiaying , Ma Mengmeng , Fang Jinghuan , Bao Jiajia , Dong Shuju , Chen Ning , Guo Yijia , He Li 
Published: September 2020

Background: Statin therapy has been shown to be effective in the prevention of ischemic stroke. In addition, recent studies have suggested that prior statin therapy could lower the initial stroke severity and improve stroke functional outcomes in the event of stroke. It was speculated that prestroke statin use may enhance collateral circulation and result in favorable functional outcomes. Objective: The aim of the study was to investigate the association of prestroke statin use with leptomeningeal collaterals and to determine the association of prestroke statin use with stroke severity and functional outcome in acute ischemic stroke patients. Methods: We prospectively and consecutively enrolled 239 acute ischemic stroke patients with acute infarction due to occlusion of the middle cerebral artery within 24 h in the neurology department of West China Hospital from May 2011 to April 2017. Computed tomographic angiography (CTA) imaging was performed for all patients to detect middle cerebral artery thrombus; regional leptomeningeal collateral score (rLMCS) was used to assess the degree of collateral circulation; the National Institutes of Health Stroke Scale (NIHSS) was used to measure stroke severity at admission; the modified Rankin scale (mRS) was used to measure outcome at 90 days; and premorbid medications were recorded. Univariate and multivariate analyses were performed. Results: Overall, 239 patients met the inclusion criteria. Fifty-four patients used statins, and 185 did not use statins before stroke onset. Prestroke statin use was independently associated with good collateral circulation (rLMCS > 10) (odds ratio [OR], 4.786; 95% confidence interval [CI], 1.195–19.171; P = 0.027). Prestroke statin use was not independently associated with lower stroke severity (NIHSS score≤14) (OR, 1.955; 95% CI, 0.657–5.816; p = 0.228), but prestroke statin use was independently associated with favorable outcome (mRS score≤2) (OR, 3.868; 95% CI, 1.325–11.289; P = 0.013). Conclusions: Our findings suggest that prestroke statin use was associated with good leptomeningeal collaterals and clinical outcomes in acute ischemic stroke (AIS) patients presenting with occlusion of the middle cerebral artery. However, clinical studies should be conducted to verify this claim.
Deformable registration and region-of-interest image reconstruction in sparse repeat CT scanning
Authors: Adelman Zeev , Joskowicz Leo 
Published: September 2020

BACKGROUND: Repeat CT scanning is ubiquitous in many clinical situations, e.g. to follow disease progression, to evaluate treatment efficacy, and to monitor interventional CT procedures. However, it incurs in cumulative radiation to the patient which can be significantly reduced by using a region of interest (ROI) and the existing baseline scan. OBJECTIVE: To obtain a high-quality reconstruction of a ROI with a significantly reduced X-ray radiation dosage that accounts for deformations. METHODS: We present a new method for deformable registration and image reconstruction inside an ROI in repeat CT scans with a highly reduced X-ray radiation dose based on sparse scanning. Our method uses the existing baseline scan data, a user-defined ROI, and a new sparse repeat scan to compute a high-quality repeat scan ROI image with a significantly reduced radiation dose. Our method first performs rigid registration between the densely scanned baseline and the sparsely scanned repeat CT scans followed by deformable registration with a low-order parametric model, both in 3D Radon space and without reconstructing the repeat scan image. It then reconstructs the repeat scan ROI without computing the entire repeat scan image. RESULTS: Our experimental results on clinical lung and liver CT scans yield a mean × 14 computation speedup and a × 7.6-12.5 radiation dose reduction, with a minor image quality loss of 0.0157 in the NRMSE metric. CONCLUSION: Our method is considerably faster than existing methods, thereby enabling intraoperative online repeat scanning that it is accurate and accounts for position, deformation, and structure changes at a fraction of the radiation dose required by existing methods.
Muslim Apocalyptic Consciousness: Representation of Imam al-Mahdi (a.s) in Literature
Authors: War Tasleem 
Published: September 2020

The concept of apocalypse is well established in all the major religions of the world, be they Semitic religions (which include, Judaism, Christianity and Islam) or Hinduism. The underlying idea behind the concept in all the religions remains the same, that is, the world will come to an end. The end itself, which has been called the Judgment Day, Day of Resurrection, or the Day of Retribution or Reckoning will be preceded by some signs. It has also been called the day of Apocalypse, the day when the whole world will be destroyed. One of the distinct forms of it is Muslim Apocalypse about which a lot has been written. However, the argument of the present research paper shall be to examine the concept of the Mahdi (a.s) primarily from the Shi’te Muslim point of view. The premise of the argument is that Shi’te argument or concept of the Mahdi (a.s) is far more substantial having a solid theoretical foundation than the other perspectives about it. No wonder, therefore, the concept of the Mahdi (a.s) has manifested itself in literature across cultures and ages. There are so many poets, primarily, Muslim poets who have highlighted this concept in their poetry and thus the research paper shall make an attempt to look at some of those poets and their understanding of it.
ОБЛИЧЧЯ СМЕРТІ: ТЕРОР ПОЛІЦІЇ БЕЗПЕКИ ТА СД ПРОТИ НАСЕЛЕННЯ ГЕНЕРАЛЬНОЇ ОКРУГИ «МИКОЛАЇВ»
Authors: Pogorielov Anatolii 
Published: September 2020

Уперше детально розкривається структура і кадровий склад апарату Управління поліції безпеки та СД генеральної округи «Миколаїв», його роль у масштабному терорі проти цивільного населення регіону. Віднайдені конкретні прізвища співробітників керівного і рядового складу, які були ініціаторами чи безпосередньо причетними до арештів, катувань, конвоювання під час масових розстрілів і показових страт. Висвітлюються основні способи вербування, а також механізм створення розгалуженої агентурної мережі із місцевих колаборантів. Уточнені місця і процедура деяких страт єврейського і ромського населення. Вводяться до наукового обігу світлина другого шефа Управління поліції безпеки та СД генеральної округи «Миколаїв» штурмбанфюрера СС д-ра Леопольда Шпанна та фото інших співробітників нацистської спецслужби. Оприлюднено креслення місцерозташування основних будівель штаб-квартири поліції безпеки та СД у Миколаєві, схеми місць масових розстрілів. Складено поіменний список зондеркоманди, учасники якої займались ліквідацією слідів злодіянь співробітників досліджуваної окупаційної спецслужби в 1943–1944 рр. З’ясовано подальший маршрут руху співробітників поліції безпеки та СД після евакуації з Миколаїва в березні 1944 р.
Ключові слова: Миколаїв, поліція безпеки та СД, терор, цивільне населення, рух Опору, єврейське і ромське населення, колаборація, Голокост.
SELEKTIVE ERINNERUNG. DER ZWEITE WELTKRIEG IN DER UKRAINE IM HISTORISCHEN GEDÄCHTNIS DER RUSSLANDDEUTSCHEN
Authors: Petersen Hans-Christian 
Published: September 2020

Der Zweite Weltkrieg stellt bis heute den zentralen Bezugspunkt jener Gruppe dar, die in der Forschung zumeist unter dem Begriff der «Russlanddeutschen» subsummiert wird. Insbesondere die kollektiven Zwangsumsiedlungen, die mit dem Erlass des Obersten Sowjets der UdSSR vom 28. August 1941 einsetzten und im Zuge derer bis Ende 1941 rund 900 000 Menschen nach Sibirien und Kasachstan umgesiedelt wurden und rund 150 000 Menschen durch Aussiedlung, Hunger oder Zwangsarbeit starben, bilden den Kern eines Opfernarrativs, das durch russlanddeutsche Verbände und ihnen nahe stehende Historiker*innen mit einem in hohem Maße emotional besetzten Absolutheitsanspruch vertreten wird. Das ist angesichts der leidvollen Erfahrung sehr verständlich, führt jedoch andererseits auch dazu, dass all jene Facetten der Geschichte ausgeblendet werden, die nicht dieser Interpretation entsprechen. Deutlich wird das an den ukrainischen Gebieten: Während die deutschsprachige Bevölkerung in der östlichen Ukraine von der stalinistischen Zwangsumsiedlungspolitik erfasst wurde, wirkte sie im Westen und den zentralen Teilen des Landes an der deutschen Besatzungs- und Vernichtungspolitik mit. Hier geht es mithin um die Frage der Ausmaße einer Täter-, und keiner Opfergeschichte. Ihre Erforschung weist zahlreiche Desiderate auf, und im «offiziellen», kulturellen Gedächtnis der Gruppe kommt sie bisher kaum vor.
In dem Beitrag wird die Entwicklung der russlanddeutschen Erinnerungsund Geschichtspolitik an die Zeit des Zweiten Weltkriegs in der Ukraine nachgezeichnet und einer kritischen Reflektion unterzogen werden. Es werden drei Gründe für die Entwicklung eines selektiven Erinnerns benannt: Die Geschichte der Landsmannschaft der Deutschen aus Russland, die gesetzliche Anerkennungspraxis der Bundesrepublik Deutschland und die sowjetische Erfahrung der Menschen. Zugleich sind die Ereignisse des Zweiten Weltkriegs in der Ukraine in den Familiengedächtnissen schwarzmeerdeutscher Familien bis heute sehr präsent. Dies wirft die Frage auf, wie ein vollständigeres, auch Widersprüche beinhaltendes Erinnern an den Zweiten Weltkrieg aussehen könnte. Hierzu werden abschließend Perspektiven einer Öffnung des russlanddeutschen kulturellen Gedächtnisses zur Diskussion gestellt.
Schlagwörter: Russlanddeutsche, Schwarzmeerdeutsche, Migration, Zweiter Weltkrieg, «Volksdeutsche», Kulturelles Gedächtnis, Selektive Erinnerung, Heterogenität.
Regulatory and legal basis of electronic governance for modernization of administrative processes in public authorities of Ukraine
Authors: Mazur Oleksandr 
Published: September 2020

In the article, we understand the term «administrative process» as the statutory procedure for public administration. The author considers the legal framework for introducing e-governance according to modernizing the activities of public administration, which are the main stages of administrative processes. The author believes the implementation of information and communication technologies is an important area for achieving greater efficiency of public administration.
The purpose of the article is to conduct a retrospective review and systematization of regulatory and legal support of Ukraine on the implementation of e-governance aimed at modernizing the administrative processes taking place in public administration.
The author examines the regulations on informatization, e-governance and digital transformation in terms of the main stages of administrative processes, namely: task definition; preparation for management decisions; decision making; bringing it to the recipients and organization of execution; control over the implementation of the decisions.
The author concludes that since the proclamation of Ukraine’s independence in 1991 to the present in regulations on the introduction of information and communication technologies in public administration areas of public policy in the field of informatization and e-governance have significantly changed the administrative processes in public administration bodies. The author states that at the first stages of informatization of public administration in regulatory and legal support the greatest attention in the introduction of information and communication technologies was paid to the main stages of administrative processes. According to the author, the basic principles of information society development in Ukraine, with their focus on citizen participation in governance, have influenced all the main stages of administrative processes. To support, the author systematizes the main stages of information systems used in public administration, namely: information systems for statistical presentation of information are introduced for the stage of «task definition»; information-analytical systems are introduced for the stages «preparation for management decision-making» and «decision-making»; for the stages of «bringing it to the addressees of the decision», «organization of execution» and «control of execution of decisions» electronic document management systems are introduced.
In the course of the analysis, the author finds out that the activities of public administration bodies such as «disclosure and access to public information» and «public services providing» in which administrative processes take place have become important. According to the author, the active phase of rule-making support of e-governance shows that the main focus is on providing administrative services in electronic form through web portals and mobile Internet services.
Informational security in the context of challenges end threats of national security
Authors: Panchenko Oleh 
Published: September 2020

The article analyzes the current problems of information security as a part of the national security of the state. The author identifies the reasons for the unsatisfactory situation in the field of information security. Particular attention is paid to the legal framework for information security and prospects for improving legislation, the problems of regulating relations in this area. Successful development and the very existence of Ukraine as a sovereign state is impossible without ensuring its national security. The society’s and the state’s information security is determined by the degree of their protection and, consequently, the stability of the main areas of life concerning dangerous, destabilizing, destructive, infringing the interests of the country information actions at both implementation, and retrieval.
The state information policy, as activity of system of public authorities and administration in the information-psychological area occupies the central place in the system of regulation of both social and political relations in the modern information society. The transparency of the state information policy is the basis for ensuring the country’s socio-psychological stability and successful economic development. The practice of information and psychological influence is more and more developing in the modern world. The terms «informational» and «psychological» wars are widely used by politicians and political scientists, and are increasingly appearing in the context of the country’s information security issues.
The purpose of this article is to determine the role of information security in the national security of the state and to study the legislative regulation in the information area of Ukraine.
A radical change in the state’s approach to solving this problem should become one of the priorities in ensuring national security.
Regional policy on sustainable development of Ukraine in the context of European integration
Authors: Melnyshyn Lev 
Published: September 2020

The article analyzes the issues of regional development in the context of modern public administration. The study of regional development is actualized by the presence of the social order and the peculiarities of development in Ukraine. The experience of realization of social and economic development of regions is generalized on an example.
The world experience of state regulation of regional development is largely differentiated due to the peculiarities and development of national economies, state system, political traditions and forms of international integration, and therefore it is almost impossible to identify the dominant model of regional development policy.
The global trend of the modern world is the growing role of regions as units of the regional level of government, which can, on the one hand, reduce the burden on central government, taking over some of their powers, and on the other - take into account the needs of local decision-making. This process is the result of decentralization, regionalization, democratization and globalization.
The long crisis period in Ukraine and the proclaimed European integration vector objectively require the implementation of a scientifically sound integrated state policy aimed at restoring economic growth and the economy to the level of global competitiveness. The regional aspect of the economic growth strategy has an exclusive role for Ukraine.
Today it is necessary to implement its own scientifically sound and balanced regional policy, harmonization of the principles of interaction of the center with the regions in order to ensure the optimal combination of national and regional interests. According to the levels of economic, technological and social development, the regions of Ukraine are significantly differentiated and the problem of leveling these disparities remains relevant.
Strategic management by the regional economic development in public administration in Ukraine
Authors: Pastukh Kateryna 
Published: September 2020

In a modern regional economy in Ukraine, there is a need to improve the mechanisms of strategic management by the regional economic development in public administration. Problems of the economic regional development in Ukraine explains the need to pay attention to strategic management by the regional economic development in the sphere of public administration.
The issue of strategic management by the regional economic development in the sphere of public administration has been covered in the scientific works. But despite active scientific researches the strategic management by the regional economic development public administration in Ukraine isn’t still studied properly.
The strategic management by the regional economic development in public administration in Ukraine have been investigated. The normative legal base of strategic management by the regional economic development in public administration in Ukraine are generalized. The main components of normative legal base of strategic management by the regional economic development in public administration in Ukraine are The Constitution of Ukraine, laws of Ukraine, Codes of Ukraine, Acts of the Cabinet of Ministers of Ukraine and others. The features of strategic planning of regional economic development in the sphere of public administration in Ukraine are considered.
In today’s conditions, the state of regional socio-economic and ecological development in Ukraine require the improvement of provision of strategic management by the regional economic development in public administration in Ukraine. The ways for improving the provision of strategic management by the regional economic development in public administration in Ukraine are determined.
Policy Brief
Authors: Lasker Shamima Parvin 
Published: September 2020

Asian Bioethics Conference (ABC20) was held on 22-25 Nov. 2019 at DGHS (Directorate General of Health Services) auditorium, Mohakhali and NEC (National Election Commission) Auditorium, Agargoan, Dhaka. Conference was organized by Bangladesh Bioethics Society (BBS) in cooperation of DGHS, Ministry of Health & Family Welfare; Social Science Research Council Bangladesh, Ministry of Planning; Bangladesh Medical Research Council, Mohakhali Dhaka; Asian Bioethics Association (ABA) and Eubios Ethics Institute, Thailand, New Zealand’s and Japan.
Mr MA Mannan MP, Honorable Planning Minister, Government of the People’s Republic of Bangladesh was the Chief Guest.
Dr. Md. Murad Hassan MP, Honorable State Minister, Ministry of Information, Government of the People's Republic of Bangladesh was present as Special Guest.
Md. Nurul Amin, Secretary, Planning Division, Ministry of Planning and Dr Iqbal Kabir, Director, Planning, Monitoring, & Research and Coordinator, DGHS were also present as Special Guests.
Bioethics promotes strong ethical values, practice of ethics and morality in Science, Social Science, Commerce and Arts.
The conference brought together scholars and policy makers from different disciplines from all around the world to discuss and deliberate the latest issues of bioethics in biomedicine, biotechnology, science, social science, education and research.
Around 300 participants from different universities and government officials including 40 foreign delegates from Asia & Pacific and beyond were present at the conference.
Safety and Efficacy of Different Therapeutic Interventions on Prevention and Treatment of COVID-19
Authors: Gyanwali Pradip , Sharma Sitasma , Pant Suman , Koirala Pallavi , Adhikari Kriti , Koirala Janak , Dhimal Meghnath 
Published: September 2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the strain of coronavirus that causes coronavirus disease 2019 (COVID-19), a respiratory illness. COVID-19 has now become a global public health crisis causing alarming numbers of morbidity and mortality. Ever since the COVID-19 pandemic started scientists, researchers, universities, companies, and institutions all around the world have been endeavoring to discover a potential treatment for COVID-19. Numerous studies and clinical trials on vaccines and drugs for the prevention and treatment of COVID-19 are underway across the world. However, the uncertainty around the efficacy and safety of various treatment regimens have become one of the biggest challenges in the battle against the SARS-CoV-2. This paper is a narrative review of articles regarding the various treatments and vaccines being tested for the SARS-CoV-2, available in the PubMed database along with Google Scholar. There are ongoing clinical trials on potential drugs such as remdesivir, favipiravir, lopinavir/ritonavir, chloroquine, and hydroxychloroquine, corticosteroids tocilizumab, azithromycin, anakinra, etc. and other therapeutic modalities like convalescent plasma therapy. Likewise, vaccines against SARS-CoV-2 are being developed and tested, including mRNA, non-replicating viral vector, DNA, protein subunit candidate vaccines, etc. Although some early-stage clinical trials and studies on these drugs and vaccines have shown positive results, definitive and conclusive results are yet to be obtained.
Keywords: COVID-19; antiviral drugs; COVID-19 treatment; COVID-19 vaccine; SARS-CoV-2
ANALISIS LAJU KEAUSAN BAJA SUJ2 HASIL VARIASI TEMPERATUR TEMPERING UNTUK APLIKASI BALL BEARING
Authors: Cahyadi Robi , Oktadinata Herry , Sadiana Riri 
Published: September 2020

Baja SUJ2 merupakan material standar internasional yang umum digunakan untuk pembuatan bearing. Ketahanan aus (wear resistance) sangat dipengaruhi oleh nilai kekerasan. Hardness yang baik dapat dicapai dengan cara memberikan perlakuan panas pada material tersebut melalui tahapan heating, quenching, lalu tempering. Tujuan dari penelitian ini adalah mengetahui secara jelas laju keausan material baja SUJ2 yang diberikan perlakuan variasi temperatur tempering. Pada penelitian ini, material baja SUJ2 mendapatkan perlakuan tempering dengan variasi nilai temperatur sebesar 170 0C, 200 0C, 230 0C. Hasil pengujian dengan alat uji aus tipe Pin on Disk (ASTM G99) menunjukkan bahwa baja SUJ2 dengan perlakuan tempering 170 0C dan pembebanan alat uji aus sebesar 4,9 N memiliki ketahan aus paling baik yaitu 0,7228 mm3/menit, sedangkan material baja SUJ2 dengan perlakuan tempering 230 0C dan pembebanan alat uji aus sebesar 14,7 N memiliki ketahanan aus paling buruk yaitu 2,3098 mm3/menit.