bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adaptive and maladaptive forms of disengagement coping in caregivers of children with chronic illnesses
Authors: Waugh Christian E. , Leslie‐Miller Calissa J. , Shing Elaine Z. , Furr R. Michael , Nightingale Chandylen L. , McLean Thomas W. 
Published: September 2020

AbstractCaregivers of children with chronic illnesses experience elevated stress and reduced self‐care. Although self‐care can be beneficial, it is a form of disengagement coping, disengaging from the stressor to try and feel better, which has been characterized as a maladaptive coping strategy. In this study, we test the formulation that avoidance, avoiding the stressor and any thoughts related to it, is a maladaptive disengagement coping strategy, whereas distraction, taking a break from the stressor to do something pleasant, is an adaptive disengagement coping strategy. We assessed these strategies as well as psychosocial outcomes and trait predictors in caregivers of children with chronic illnesses. Results showed that those high in avoidance coping reported lower well‐being, higher depression and higher stress. Alternatively, when controlling for avoidance, those high in distraction reported higher well‐being, lower depression and lower stress. In addition, distraction exhibited strong relationships to increased positive emotions during caregiving situations and was associated with positive personality traits. These results suggest that not all disengagement coping strategies are equal; although avoidance may be a maladaptive strategy, distraction can be an effective positive emotional strategy for coping with the chronic stress of caregiving for a child with a chronic illness.
Lead‐Free Dual‐Phase Halide Perovskites for Preconditioned Conducting‐Bridge Memory
Authors: Han Ji Su , Le Quyet Van , Kim Hyojung , Lee Yoon Jung , Lee Da Eun , Im In Hyuk , Lee Min Kyung , Kim Seung Ju , Kim Jaehyun , Kwak Kyung Ju , Choi Min‐Ju , Lee Sol A , Hong Kootak , Kim Soo Young , Jang Ho Won 
Published: September 2020

AbstractOrganometallic and all‐inorganic halide perovskites (HPs) have recently emerged as promising candidate materials for resistive switching (RS) nonvolatile memory due to their current–voltage hysteresis caused by fast ion migration. Lead‐free and all‐inorganic HPs have been researched for non‐toxic and environmentally friendly RS memory devices. However, only HP‐based devices with electrochemically active top electrode (TE) exhibit ultra‐low operating voltages and high on/off ratio RS properties. The active TE easily reacts to halide ions in HP films, and the devices have a low device durability. Herein, RS memory devices based on an air‐stable lead‐free all‐inorganic dual‐phase HP (AgBi2I7‐Cs3Bi2I9) are successfully fabricated with inert metal electrodes. The devices with Au TE show filamentary RS behavior by conducting‐bridge involving Ag cations in HPs with ultra‐low operating voltages (<0.15 V), high on/off ratio (>107), multilevel data storage, and long retention times (>5 × 104 s). The use of a closed‐loop pulse switching method improves reversible RS properties up to 103 cycles with high on/off ratio above 106. With an extremely small bending radius of 1 mm, the devices are operable with reasonable RS characteristics. This work provides a promising material strategy for lead‐free all‐inorganic HP‐based nonvolatile memory devices for practical applications.
Ameliorative effect of ferruginol on isoprenaline hydrochloride‐induced myocardial infarction in rats
Authors: Zhang Xudong , Li Xiaojiang , Wang Chunlan , Li Haijun , Wang Lijun , Chen Yu , Feng Jingbin , Ali Alharbi Sulaiman , Deng Yue 
Published: September 2020

AbstractCardiovascular‐related diseases continue to be a leading cause of death globally. Among ischemic‐induced cardiac diseases, myocardial infarction (MI) is reported to be of an alarming value. Despite numerous improvements in the medical intrusions, still this armamentarium fails to be effective in managing the illness without setbacks. Ferruginol (FGL) is a major polyphenols and terpenoids with numerous pharmacological activities including antioxidant and anti‐inflammatory. Following, this work was aimed to explore the cardio protective effect of FGL (50 mg/kg) in isoprenaline hydrochloride (ISO)‐induced MI in experimental rats. After treatment with FGL in ISO‐induced MI in rats, noticeable changes were observed in the experimental rats. Injection of ISO to rats resulted in the augmented cardiac weight, serum cardiac markers (creatine kinase, creatine kinase‐MB, cardiac troponin T, and Cardiac troponin I), lipid peroxidation end products (thiobarbituric acid‐reactive substance and lipid hydroperoxides), reduced endogenous antioxidants (superoxide dismutase, catalase, glutathione peroxidase, and glutathione), reduced ATPase activity, and escalated pro‐inflammatory cytokines (interleukin‐6, tumor necrosis factor‐α, and nuclear factor‐κB) levels. Interestingly, the FGL supplementation to the ISO‐treated rats revealed the diminished heart weight, reduced cardiac markers, and lipid peroxidation. FGL also possessed the improved antioxidants status and diminished pro‐inflammatory mediator levels. The outcomes of histological analysis also evidenced the cardio protective role of FGL. Treatment with FGL reduced the cardiac damage biomarkers maintained to near normal levels in ISO‐induced rats. These study findings disclose the prospective capability of FGL in the treatment of MI in the future.
Jet substructure from dark sector showers
Authors: Cohen Timothy , Doss Joel , Freytsis Marat 
Published: September 2020

Abstract
We examine the robustness of collider phenomenology predictions for a dark sector scenario with QCD-like properties. Pair production of dark quarks at the LHC can result in a wide variety of signatures, depending on the details of the new physics model. A particularly challenging signal results when prompt production induces a parton shower that yields a high multiplicity of collimated dark hadrons with subsequent decays to Standard Model hadrons. The final states contain jets whose substructure encodes their non-QCD origin. This is a relatively subtle signature of strongly coupled beyond the Standard Model dynamics, and thus it is crucial that analyses incorporate systematic errors to account for the approximations that are being made when modeling the signal. We estimate theoretical uncertainties for a canonical substructure observable designed to be sensitive to the gauge structure of the underlying object, the two-point energy correlator $$ {e}_2^{\left(\beta \right)} $$

e
2

β

, by computing envelopes between resummed analytic distributions and numerical results from Pythia. We explore the separability against the QCD background as the confinement scale, number of colors, number of flavors, and dark quark masses are varied. Additionally, we investigate the uncertainties inherent to modeling dark sector hadronization. Simple estimates are provided that quantify one’s ability to distinguish these dark sector jets from the overwhelming QCD background. Such a search would benefit from theory advances to improve the predictions, and the increase in statistics using the data to be collected at the high luminosity LHC.
The neutrino Casimir force
Authors: Costantino Alexandria , Fichet Sylvain 
Published: September 2020

Abstract
In the low energy effective theory of the weak interaction, a macroscopic force arises when pairs of neutrinos are exchanged. We calculate the neutrino Casimir force between plates, allowing for two different mass eigenstates within the loop. We also provide the general potential between point sources. We discuss the possibility of distinguishing whether neutrinos are Majorana or Dirac fermions using these quantum forces.
Recidivism at the puerto rico trauma hospital
Authors: Suárez-Cruz Adriana , Ramos-Meléndez Ediel O. , Nieves-Plaza Mariely , Guerrios Lourdes , Rodríguez-Ortiz Pablo 
Published: September 2020

Abstract
Purpose
Although trauma represents a leading cause of morbidity and mortality worldwide, there is limited and heterogeneous evidence regarding trauma recidivism and its outcomes. This analysis determined the rate and independent risk factors of trauma recidivism and compared the first and second injury episode among recidivists.

Methods
An IRB-approved retrospective cohort study was performed with data from the Puerto Rico Trauma Hospital Registry. Bivariate analyses were done using Pearson’s Chi squared, Wilcoxon rank-sum, McNemar, Stuart-Maxwell or Wilcoxon signed-rank tests, as appropriate. Independent predictors for recidivism were determined through a logistic regression model. Statistical significance was set at p < 0.05.

Results
24,650 patients were admitted to the hospital during 2000–2017. Recidivism rate was 14 per 1,000 patients discharged alive. Males and individuals aged 15–24 years old were 3.88 (95% CI: 2.21–6.80) and 3.80 (95% CI: 2.24–6.46) times more likely to be recidivists, respectively. Contrariwise, an ISS $$\ge$$
≥
25 [adjusted odds ratio (AOR) = 0.44; 95% CI: 0.28–0.68] and a GCS $$\le$$
≤
8 (AOR = 0.56; 95% CI 0.34–0.92) were protective factors. Furthermore, recidivists exhibited less in-hospital mortality than their non-recidivist counterparts (7.2% vs. 10.7%; p = 0.045).
For recidivists, the median (interquartile range) time to reinjury was 42 (59) months; and the second injury episode was more severe than the first one, as the proportion of patients with ISS $$\ge$$
≥
25 increased (7.9% vs. 14.1%; p = 0.022).

Conclusion
The independent predictors of trauma recidivism and the median time to reinjury identified in this study provide valuable information to the development of prevention strategies aimed at reducing the burden of injury.
Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions: a patient-level pooled analysis from the Disrupt CAD I and CAD II Studies
Authors: Blachutzik Florian , Honton Benjamin , Escaned Javier , Hill Jonathan M. , Werner Nikos , Banning Adrian P. , Lansky Alexandra J. , Schlattner Sophia , De Bruyne Bernard , Di Mario Carlo , Dörr Oliver , Hamm Christian , Nef Holger M. 
Published: September 2020

AbstractBackgroundThe aim of this study was to assess the safety and effectiveness of intravascular lithotripsy (IVL) in treating eccentric calcified coronary lesions.MethodsBetween December 2015 and March 2019, 180 patients were enrolled in the Disrupt CAD I and CAD II studies across 19 sites in 10 countries. Patient-level data were pooled from these two studies (n = 180), within which 47 eccentric lesions (26%) and 133 concentric lesions were identified.ResultsClinical success, defined as residual stenosis < 50% after stenting and no in-hospital MACE, was similar between the eccentric and concentric cohorts (93.6% vs. 93.2%,p = 1.0). There were no perforations, abrupt closure, slow flow or no reflow events observed in either group, and there were low rates of flow-limiting dissections (Grade D–F: 0% eccentric, 1.7% concentric;p = 0.54). Final acute gain and percent residual stenosis were similar between the two groups. Final residual stenosis of 8.6 ± 9.8% in eccentric and 10.0 ± 9.0% (p = 0.56) in concentric stenosis confirms the significant effect of IVL in calcified coronary lesions.ConclusionIn this first report from a pooled patient-level analysis of coronary IVL from the Disrupt CAD I and CAD II studies, IVL use was associated with consistent improvement in procedural and clinical outcomes in both eccentric and concentric calcified lesions.
Besteht ein Zusammenhang zwischen der peripheren arteriellen Verschlusskrankheit und Parodontitis?
Authors: Aarabi G. , Jacobi N. , Kaschwich M. , Walther C. , Raedel M. , Debus E. S. , Larena-Avellaneda A. , Seedorf U. , Heydecke G. , Behrendt C.-A. 
Published: September 2020

ZusammenfassungDie periphere arterielle Verschlusskrankheit (PAVK) ist die häufigste Durchblutungsstörung peripherer Gefäße. Die PAVK wird durch Risikofaktoren und Komorbiditäten, wie zum Beispiel Rauchen, Bluthochdruck, Dyslipidämie, Diabetes und chronische Niereninsuffizienz begünstigt. Epidemiologische Studien weisen allerdings auch darauf hin, dass zusätzlich die Parodontitis (PA) das Risiko für eine PAVK erhöhen kann. Die PA ist eine häufige, durch bakteriellen Biofilm ausgelöste, chronische Entzündung des Zahnhalteapparates. Parodontitis wird durch mangelhafte Mundhygiene, Rauchen und Diabetes begünstigt und die Prävalenz steigt mit dem Alter an. Beide Erkrankungen bzw. deren Symptome sind therapierbar, wenn die Behandlung frühzeitig einsetzt. Deshalb ist die Früherkennung besonders wichtig. Obwohl der Nachweis einer kausalen Rolle der PA für die Entstehung der PAVK noch aussteht, unterstützen die in diesem Artikel zusammengefassten Daten den Vorschlag einer interdisziplinären Zusammenarbeit zwischen Gefäß- und Zahnmedizinern. Es kann in der gefäßmedizinischen Praxis erwogen werden, PAVK-Patienten, unabhängig vom Stadium ihrer Erkrankung, zwecks Diagnose und Behandlung einer PA an Zahnärzt*innen zu verweisen. Umgekehrt sollten auch Zahnärzt*innen erwägen, Patienten, die an einer schweren Form der PA leiden, an Gefäßmediziner zu verweisen.
Non-porous organic crystals and their interaction with guest molecules from the gas phase
Authors: Casco Mirian Elizabeth , Krupp Felix , Grätz Sven , Schwenger Alexander , Damakoudi Vassiliki , Richert Clemens , Frey Wolfgang , Borchardt Lars 
Published: September 2020

AbstractSome organic molecules encapsulate solvents upon crystallization. One class of compounds that shows a high propensity to form such crystalline solvates are tetraaryladamantanes (TAAs). Recently, tetrakis(dialkoxyphenyl)-adamantanes have been shown to encapsulate a wide range of guest molecules in their crystals, and to stabilize the guest molecules against undesired reactions. The term ‘encapsulating organic crystals’ (EnOCs) has been coined for these species. In this work, we studied the behavior of three TAAs upon exposition to different guest molecules by means of sorption technique. We firstly measured the vapor adsorption/desorption isotherms with water, tetrahydrofuran and toluene, and secondly, we studied the uptake of methane on dry and wet TAAs. Uptake of methane beyond one molar equivalent was detected for wet crystals, even though the materials showed a lack of porosity. Thus far, such behavior, which we ascribe to methane hydrate formation, had been described for porous non-crystalline materials or crystals with detectable porosity, not for non-porous organic crystals. Our results show that TAA crystals have interesting properties beyond the formation of conventional solvates. Gas-containing organic crystals may find application as reservoirs for gases that are difficult to encapsulate or are slow to form crystalline hydrates in the absence of a host compound.Wet tetraaryladamantane crystals take up methane in form of methane hydrate structure I, even though they appear non-porous to argon.
Bark decomposition in white oak soil outperforms eastern hemlock soil, while bark type leads to consistent changes in soil microbial composition
Authors: Malik Rondy J. , Trexler Ryan V. , Eissenstat David M. , Bell Terrence H. 
Published: September 2020

AbstractBark decomposition is an underexamined component of soil carbon cycling and soil community assembly. Numerous studies have shown faster decomposition of leaf litter in “home” environments (i.e. within soil adjacent to the plant that produced the leaves), suggesting potential legacy effects from previous deposition of similar litter. This is expected to occur through, in part, accumulation of microorganisms that metabolize substrates the litter provides. Whether a similar “home-field advantage” (HFA) exists for bark decomposition is unknown, but this dynamic may differ because annual bark deposits to soil are minimal relative to leaf deposits. We hypothesized that (1) as with leaf litter, bark will be better decomposed near to the tree from which it was collected, and (2) that decomposing bark can initiate change in soil microbial composition. To test these hypotheses, we used a full factorial design that included two bark types (collected from eastern hemlock,Tsuga canadensis, and white oak,Quercus alba) and two soil types (‘home’ and ‘away’) within a temperate mixed hardwood forest at the Shale Hills Catchment in central Pennsylvania, USA. Bark was excised from 25 replicates of each tree type, buried in either home or away soil, and incubated belowground from July 2017 to June 2018. Decomposition was assessed through proportionate mass loss over time, while microbial composition in the bark and adjacent soil was assessed through high-throughput sequencing of 16S rRNA gene and fungal ITS fragments. Overall, bark degraded faster in white oak soils, and there was also an effect of bark type on decomposition. Although white oak bark decomposed more quickly in its home environment, this could be due to either soil conditioning or inherent differences in the soils in which each species grows. Soil microbial assemblages also sorted according to bark type rather than soil type, suggesting that bark strongly influences the composition of nearby microorganisms during decomposition. Our results suggest that both bark type and soil type are important factors during bark decomposition, but our findings suggest no clear evidence for HFA.
The prognostic and predictive role of the neutrophil-to-lymphocyte ratio and the monocyte-to-lymphocyte ratio in early breast cancer, especially in the HER2+ subtype
Authors: Tiainen Satu , Rilla Kirsi , Hämäläinen Kirsi , Oikari Sanna , Auvinen Päivi 
Published: September 2020

Abstract
Purpose
The aim of this study was to investigate the prognostic impact of two systemic inflammatory markers, the neutrophil-to-lymphocyte ratio (NLR) and the monocyte-to-lymphocyte ratio (MLR), and their possible predictive role regarding the efficacy of adjuvant trastuzumab, in 209 early breast cancer cases, 107 of which were HER2-positive.

Methods
Baseline NLR and MLR values were divided into two groups, high and low, according to cut-off-points determined from the ROC curve (2.2 for NLR and 0.22 for MLR). Cox’s model was utilized for survival analyses.

Results
High NLR and MLR correlated with poor overall survival (OS) and breast cancer specific survival (BCSS) among all the patients (p ≤ 0.030). Among the HER2+ patients whose adjuvant treatment did not include trastuzumab (n = 64), the survival rates were remarkably lower in patients with a high NLR as compared to those with low; 31% vs. 71% for OS and 42% vs. 74% for BCSS (p ≤ 0.014). Similarly, high MLR correlated with poor survival among these patients (p ≤ 0.020). On the contrary, among the patients who had received adjuvant trastuzumab (n = 43), NLR or MLR did not correlate with survival. Furthermore, trastuzumab was beneficial for the HER2+ patients with high NLR/MLR, while the survival of the HER2+ patients with low NLR/MLR was good irrespective if they received adjuvant trastuzumab.

Conclusions
Our results suggest that trastuzumab modulates the systemic inflammatory conditions and overcomes the poor prognostic impact of high NLR/MLR. This finding may also provide a rationale for combining trastuzumab with immuno-oncological treatments in HER2+ breast cancer.
Direct Current Cardioversion in Atrial Fibrillation Patients on Edoxaban Therapy Versus Vitamin K Antagonists: a Real-world Propensity Score–Matched Study
Authors: Rago Anna , Papa Andrea Antonio , Attena Emilio , Parisi Valentina , Golino Paolo , Nigro Gerardo , Russo Vincenzo 
Published: September 2020

Abstract
Purpose
The purpose of the present study was to compare the long-term effectiveness and safety of newly initiated anticoagulation with edoxaban (EDO) versus uninterrupted vitamin K antagonist (VKA) therapy in patients with atrial fibrillation (AF) scheduled for transesophageal echocardiogram (TEE)-guided direct electrical current cardioversion (DCC).

Methods
A propensity score-matched cohort observational study was performed comparing the safety and effectiveness of edoxaban versus well-controlled VKA therapy among a cohort of consecutive non-valvular AF patients scheduled for DCC. The primary safety outcome was major bleeding. The primary efficacy outcome was the composite of stroke, transient ischemic attack (TIA), and systemic embolism (SE).

Findings
A total of 130 AF patients receiving edoxaban 60-mg (EDO) treatment were compared with the same number of VKA recipients. The cumulative incidence of major bleedings was 1.54% in the EDO group and 3.08% in the VKA group (P = 0.4). The cumulative incidence of thromboembolic events was 1.54% in the EDO group and 2.31% in the VKA group (P = 0.9). A non-significant trend in improved adherence was observed between the EDO and VKA groups with a total anticoagulant therapy discontinuation rate of 4.62% (6/130) vs 6.15% (8/130), respectively (P = 0.06).

Implications
Our study provides the evidence of a safe and effective use of edoxaban in this clinical setting, justified by no significant difference in major bleedings and thromboembolic events between edoxaban and well-controlled VKA treatments.
Past Wars in Present Stories: An Analysis of the Picturebook Vanishing Colors
Authors: Neraas Silje 
Published: September 2020

AbstractIn a time when war has forced a vast number of children to flee their homes, flight from war is an important and timely topic explored in a variety of ways in contemporary picturebooks. The Norwegian picturebook Fargene som forsvant (2017)—or Vanishing Colors (2019)—addresses the topic through the story of an unnamed girl’s experience of having to leave her home. Vanishing Colors does not shield the reader from the terrible harm war does to individuals; it examines the experience of losing one’s home and former life. By analysing the picturebook in light of the concept of cultural memory, this article explores Vanishing Colors’ use of intertextual and intervisual references to past narratives of war and flight. I examine these references as part of our “collective knowledge” (Assmann 1995, p. 132), which allows the picturebook to recount both the story of an individual and a collective experience of war and flight.
Issues on the use of a modified Bunch and Kaufman decomposition for large scale Newton’s equation
Authors: Caliciotti Andrea , Fasano Giovanni , Potra Florian , Roma Massimo 
Published: September 2020

AbstractIn this work, we deal with Truncated Newton methods for solving large scale (possibly nonconvex) unconstrained optimization problems. In particular, we consider the use of a modified Bunch and Kaufman factorization for solving the Newton equation, at each (outer) iteration of the method. The Bunch and Kaufman factorization of a tridiagonal matrix is an effective and stable matrix decomposition, which is well exploited in the widely adopted SYMMBK (Bunch and Kaufman in Math Comput 31:163–179, 1977; Chandra in Conjugate gradient methods for partial differential equations, vol 129, 1978; Conn et al. in Trust-region methods. MPS-SIAM series on optimization, Society for Industrial Mathematics, Philadelphia, 2000; HSL, A collection of Fortran codes for large scale scientific computation, http://www.hsl.rl.ac.uk/; Marcia in Appl Numer Math 58:449–458, 2008) routine. It can be used to provide conjugate directions, both in the case of $$1\times 1$$

1
×
1

and $$2\times 2$$

2
×
2

pivoting steps. The main drawback is that the resulting solution of Newton’s equation might not be gradient–related, in the case the objective function is nonconvex. Here we first focus on some theoretical properties, in order to ensure that at each iteration of the Truncated Newton method, the search direction obtained by using an adapted Bunch and Kaufman factorization is gradient–related. This allows to perform a standard Armijo-type linesearch procedure, using a bounded descent direction. Furthermore, the results of an extended numerical experience using large scale CUTEst problems is reported, showing the reliability and the efficiency of the proposed approach, both on convex and nonconvex problems.