bluuebunny/crossref_metadata_2025_split huggingface dataset:
A possible physical mechanism of the torque generation of the bacterial flagellar motor
Authors: Chou Y. C. 
Published: January 2020

AbstractThe torque required for the rotation of the rotor of a bacterial flagellar motor (BFM) can be generated from an impulsive force resulting from the collision between the stator and the rotor. The asymmetry in the fluctuations of the tilting angle of the rotor determines the direction of rotation. The expressions of the torque and the step size can be derived from a Langevin equation of motion. The drag coefficient of BFM derived from the Langevin equation and the measured torque–speed (τ-ω) relation is notably high; the viscous force from the environment cannot account for it. The drag force may be caused by the frictional interaction between the bearing-like L- and P-rings of BFM and the cell membrane. Order-of-magnitude estimations of the torque and the step size are consistent with previous experimental observations. The slope of the linear dependence of the rotational frequency on the temperature was estimated and was consistent with the observed value. A simulation device having the structural characteristics of BFM was designed to demonstrate the applicability of the proposed mechanism. Many observations for the actual BFM, such as the bidirectional rotation and the τ-ω relations of the clockwise and counterclockwise rotations, were reproduced in the simulation experiments.ImportanceThe concept that the torque required for the rotation of the rotor of a bacterial flagellar motor (BFM) can be generated from an impulsive force resulting from the collision between the stator and the rotor is new and effective. The magnitude of the torque and the size of the step derived from the proposed mechanism are consistent with the observed values. The torque-speed (τ-ω) relation might be explained by the frequency-dependent drag force caused by the frictional interaction between the bearing-like L- and P-rings of BFM and the cell membrane. The slope of the linear dependence of the rotational frequency on the temperature is consistent with the observed value, which has not been achieved previously.
Suppression of Cytotoxic T Cell Functions and Decreased Levels of Tissue Resident Memory T cell During H5N1 infection
Authors: Kandasamy Matheswaran , Furlong Kevin , Perez Jasmine T. , Manicassamy Santhakumar , Manicassamy Balaji 
Published: January 2020

AbstractSeasonal influenza virus infections cause mild illness in healthy adults, as timely viral clearance is mediated by the functions of cytotoxic T cells. However, avian H5N1 influenza virus infections can result in prolonged and fatal illness across all age groups, which has been attributed to the overt and uncontrolled activation of host immune responses. Here we investigate how excessive innate immune responses to H5N1 impair subsequent adaptive T cell responses in the lungs. Using recombinant H1N1 and H5N1 strains sharing 6 internal genes, we demonstrate that H5N1 (2:6) infection in mice causes higher stimulation and increased migration of lung dendritic cells to the draining lymph nodes, resulting in higher numbers of virus specific T cells in the lungs. Despite robust T cell responses in the lungs, H5N1 (2:6) infected mice showed inefficient and delayed viral clearance as compared to H1N1 infected mice. In addition, we observed higher levels of inhibitory signals including increased PD1 and IL-10 expression by cytotoxic T cells in H5N1 (2:6) infected mice, suggesting that delayed viral clearance of H5N1 (2:6) was due to suppression of T cell functionsin vivo. Importantly, H5N1 (2:6) infected mice displayed decreased numbers of tissue resident memory T cells as compared to H1N1 infected mice; however, despite decreased number of tissue resident memory T cells, H5N1 (2:6) were protected against a heterologous challenge from H3N2 virus (X31). Taken together, our study provides mechanistic insight for the prolonged viral replication and protracted illness observed in H5N1 infected patients.ImportanceInfluenza viruses cause upper respiratory tract infections in humans. In healthy adults, seasonal influenza virus infections result in mild disease. Occasionally, influenza viruses endemic in domestic birds can cause severe and fatal disease even in healthy individuals. In avian influenza virus infected patients, the host immune system is activated in an uncontrolled manner and is unable to control infection in a timely fashion. In this study, we investigated why the immune system fails to effectively control a modified form of avian influenza virus. Our studies show that T cell functions important for clearing virally infected cells are impaired by higher negative regulatory signals during modified avian influenza virus infection. In addition, memory T cell numbers were decreased in modified avian influenza virus infected mice. Our studies provide a possible mechanism for the severe and prolonged disease associated with avian influenza virus infections in humans.
Nanoscale Structure Determination of Murray Valley Encephalitis and Powassan Virus Non-coding RNAs
Authors: Mrozowich Tyler , Henrickson Amy , Demeler Borries , Patel Trushar R 
Published: January 2020

AbstractViral infections are responsible for numerous deaths worldwide. Flaviviruses, which contain RNA as their genetic material, are one of the most pathogenic families of viruses. There is an increasing amount of evidence suggesting that their 5’ and 3’ non-coding terminal regions are critical for their survival. In this study, the 5’ and 3’ terminal regions of Murray Valley Encephalitis and Powassan virus were examined using biophysical and computational modeling methods. First, the purity ofin-vitrotranscribed RNAs were investigated using size exclusion chromatography and analytical ultracentrifuge methods. Next, we employed small-angle X-ray scattering techniques to study solution conformation and low-resolution structures of these RNAs, which suggested that the 3’ terminal regions are highly extended, compared to the 5’ terminal regions for both viruses. Using computational modeling tools, we reconstructed 3-dimensional structures of each RNA fragment and compared them with derived small-angle X-ray scattering low-resolution structures. This approach allowed us to further reinforce that the 5’ terminal regions adopt more dynamic structures compared to the mainly double-stranded structures of the 3’ terminal regions.
Rethinking corruption on fiscal decentralization and global competitiveness Nexus
Authors: Chalil Tengku Munawar 
Published: January 2020

PurposeThis study investigates the effects of fiscal decentralization on global competitiveness through the level of corruption. This study aims to clarify the causal impacts of fiscal decentralization policy on the achievement of competitiveness rank considering the degree of corruption in a country.Design/methodology/approachThe paper uses an empirical study using both cross-country arithmetic mean and panel data, covering ten-year period (2005-2014). The analysis uses both linear and non-linear specification in search of actual intermediating effects of corruption with controlling the possible endogeneity.FindingsThe paper provides empirical insights about corruption effects of fiscal decentralization on global competitiveness. It suggests that increasing level of fiscal decentralization has a positive contribution to competitiveness for the less-corrupt countries. The adverse effects appear for corrupt countries where the delegation of fiscal authority should endanger the country competitiveness.Research limitations/implicationsThis research exploits the well-known measurement of fiscal decentralization, the degree of corruption and competitiveness. Therefore, this measurement might be challenged for representing the real concept of decentralization, corruption and competitiveness, furthermore its relationship. Despite the limitation, this research explores the entanglement of fiscal decentralization, corruption and competitiveness.Practical implicationsThe paper provides the implications for the national policymakers about decentralizing the fiscal authority to achieve higher competitiveness level, through assessing their state of corruption.Originality/valueThe research provides additional comments for Oates’ (1972) decentralization theorem in connection to competitiveness, by adding corruption level as pre-requisite condition.
Management approach for innovation success in unstable and stable environments
Authors: Abidi Dora , Koichi Nakagawa 
Published: January 2020

PurposeThis paper aims to examine the management approaches that play a key role for innovation success in a stable and unstable environment.Design/methodology/approachTunisia and Japan were chosen as a research sites to assess the accuracy of management approach adopted in each environment. Japan, as a developed, stable and predictable market, involves a traditional/conventional management mode known as administrative control approach (ACA) for successful innovation. However, we argue that a developing country is characterized by its unstable environment and requires an opportunity-based approach (OBA) that lies in the firm’s openness to search and benefit from environmental opportunities.FindingsThe paper confirms that OBA improves product innovation success in an unstable environment, for innovation in a stable one.Originality/valueThe paper provides a comprehensive comparison between innovation driven management approaches towards stable and unstable environments through multi-group structural equation modeling.
Managing technological innovation in the sports industry: a challenge for retail management
Authors: Vrontis Demetris , Viassone Milena , Serravalle Francesca , Christofi Michael 
Published: January 2020

Purpose
The purpose of this paper is twofold: first, to investigate the effects of the digitalization process on the demand and supply side in the sports world through the advent of mobile apps and online services, such as YouTube, which provide free (or almost) real fitness courses; and second, to investigate how technological innovation is managed in the sports sector.

Design/methodology/approach
Drawing on a survey research approach, this study collected 150 questionnaires from consumers in the North of Italy.

Findings
Based on a descriptive analysis of the data, the findings show that the digital channel becomes significant at an exponential rate and takes on a leading role in today’s era, especially among young people. However, the results also show that the traditional channel of use of the sports service (gyms/fitness centers) is privileged by consumers under the age of 35, even though there is a weak penetration of innovative tools offered by the innovation technology (mobile app and video tutorials on social networks such as YouTube) in the sports sector.

Practical implications
The study provides an exhaustive overview of academic literature on technology and innovation management, and provides the contact point between the physical and digital world in the sports sector, and adds a significant scholarly and practical value in the exercise at home perspective of consumers. This research also contributes to the discussion on the competitiveness between the two channels (physical and digital one) in the sports sector, thus giving rise to further research concerning the offer of the type of sports service.

Originality/value
This study is among the few that connect the technological advancements and management within the sports industry and provides the ground and theoretical basis for the scholar community to further build on.
The fit of competitive strategies and firm-specific advantages with country-specific advantages in explaining manufacturing location choices
Authors: Akpinar Murat 
Published: January 2020

Purpose
This paper aims to clarify the fit of competitive strategies and firm-specific advantages (FSAs) with country-specific advantages (CSAs) in explaining manufacturing location choices at product category level in the European automotive industry.

Design/methodology/approach
Seven hypotheses are formulated and tested using binomial logistic regression with data from 148 passenger car models (i.e. product category level) that are sold in Europe and manufactured in countries that offer CSAs of either cost advantages or differentiation advantages. The first four hypotheses test manufacturing location choices of product categories pursuing cost leadership strategy, differentiation strategy, focus strategy and hybrid strategy. The other three hypotheses test whether FSAs of R&D capability, marketing capability and operations capability will impact on the manufacturing location choice. The tests control for the type of passenger cars as well as the manufacturer’s region of origin.

Findings
While pursuing cost leadership strategy leads to manufacturing in countries that offer cost advantages, pursuing differentiation strategy as well as strong R&D capability and marketing capability result in manufacturing in countries that offer differentiation advantages. Focus strategy, hybrid strategy and operations capability do not have an impact on the manufacturing location choice at product category level.

Research limitations/implications
Conducting empirical research at product category level is subject to limitations in the choices of FSAs due to lack of availability of data.

Practical implications
Managers should assess the competitive strategies and FSAs of their product categories and then decide about manufacturing locations based on their fit with host country CSAs. Policymakers should understand the CSAs of their countries and target to attract manufacturing FDI from product categories with matching competitive strategies and FSAs.

Originality/value
The research contributes to discussions in explaining manufacturing location choices. Its originality lies in being the first study to test the fit of competitive strategies and FSAs of product categories with CSAs.
Solution for free vibration of spatial curved beams
Authors: Wang Guangxin , Zhu Lili , Higuchi Ken , Fan Wenzhong , Li Linjie 
Published: January 2020

Purpose
The purpose of this paper is to propose and analyze the free vibration response of the spatial curved beams with variable curvature, torsion and cross section, in which all the effects of rotary inertia, shear and axial deformations can be considered.

Design/methodology/approach
The governing equations for free vibration response of the spatial curved beams are derived in matrix formats, considering the variable curvature, torsion and cross section. Frobenius’ scheme and the dynamic stiffness method are applied to solve these equations. A computer program is coded in Mathematica according to the proposed method.

Findings
To assess the validity of the proposed solution, a convergence study is carried out on a cylindrical helical spring with a variable circular cross section, and a comparison is made with the finite element method (FEM) results in ABAQUS. Further, the present model is used for reciprocal spiral rods with variable circular cross section in different boundary conditions, and the comparison with FEM results shows that only a limited number of terms in the results provide a relatively accurate solution.

Originality/value
The numerical results show that only a limited number of terms are needed in series solutions and in the Taylor expansion series to ensure an accurate solution. In addition, with a simple modification, the present formulation is easy to extend to analyze a more complicated model by combining with finite element solutions or analyze the transient responses and stochastic responses of spatial curved beams by Laplace transformation or Fourier transformation.
Rapid multi-objective optimization of antennas using nested kriging surrogates and single-fidelity EM simulation models
Authors: Koziel Slawomir , Pietrenko-Dabrowska Anna 
Published: January 2020

Purpose
This study aims to propose a computationally efficient framework for multi-objective optimization (MO) of antennas involving nested kriging modeling technology. The technique is demonstrated through a two-objective optimization of a planar Yagi antenna and three-objective design of a compact wideband antenna.

Design/methodology/approach
The keystone of the proposed approach is the usage of recently introduced nested kriging modeling for identifying the design space region containing the Pareto front and constructing fast surrogate model for the MO algorithm. Surrogate-assisted design refinement is applied to improve the accuracy of Pareto set determination. Consequently, the Pareto set is obtained cost-efficiently, even though the optimization process uses solely high-fidelity electromagnetic (EM) analysis.

Findings
The optimization cost is dramatically reduced for the proposed framework as compared to other state-of-the-art frameworks. The initial Pareto set is identified more precisely (its span is wider and of better quality), which is a result of a considerably smaller domain of the nested kriging model and better predictive power of the surrogate.

Research limitations/implications
The proposed technique can be generalized to accommodate low- and high-fidelity EM simulations in a straightforward manner. The future work will incorporate variable-fidelity simulations to further reduce the cost of the training data acquisition.

Originality/value
The fast MO optimization procedure with the use of the nested kriging modeling technology for approximation of the Pareto set has been proposed and its superiority over state-of-the-art surrogate-assisted procedures has been proved. To the best of the authors’ knowledge, this approach to multi-objective antenna optimization is novel and enables obtaining optimal designs cost-effectively even in relatively high-dimensional spaces (considering typical antenna design setups) within wide parameter ranges.
Effect of groove shape on the hydrodynamic lubrication of journal bearing considering cavitation
Authors: Chen Yu , Feng Jun , Sun Y. , Peng Xu , Dai Qiao , Yu Chengtao 
Published: January 2020

Purpose
The purpose of this study is to investigate the influence of groove shape on the hydrodynamic characteristics of a journal bearing.

Design/methodology/approach
The computational fluid dynamics model also takes into account the cavitation phenomena and thermal effect, which can illustrate the lubrication performance of a journal bearing.

Findings
The hydrodynamic simulations of the journal bearing with the different groove shapes are conducted under different operation conditions.

Originality/value
Based on the numerical analysis, the suggestions are presented for groove shape selection and can be used to the design of a journal bearing under the extreme operation condition.
Analysis of the predictive effect and feedback control in an extended lattice hydrodynamic model
Authors: Li Lixiang , Ge Hongxia , Cheng Rongjun 
Published: January 2020

Purpose
This paper aims to put forward an extended lattice hydrodynamic model, explore its effects on alleviating traffic congestion and provide theoretical basis for traffic management departments and traffic engineering implementation departments.

Design/methodology/approach
The control method is applied to study the stability of the new model. Through nonlinear analysis, the mKdV equation representing kink-antikink soliton is acquired.

Findings
The predictive effect and the control signal can enhance the traffic flow stability and reduce the energy consumption.

Originality/value
The predictive effect and feedback control are first considered in lattice hydrodynamic model simultaneously. Numerical simulations demonstrate that these two factors can enhance the traffic flow stability.
Measuring book impact via content-level academic review mining
Authors: Zhou Qingqing , Zhang Chengzhi 
Published: January 2020

Purpose
As for academic papers, the customary methods for assessing the impact of books are based on citations, which is straightforward but limited to the coverage of databases. Alternative metrics can be used to avoid such limitations, such as blog citations and library holdings. However, content-level information is generally ignored, thus overlooking users’ intentions. Meanwhile, abundant academic reviews express scholars’ opinions on books, which can be used to assess books’ impact via fine-grained review mining. Hence, this study aims to assess books’ use impacts by conducting content mining of academic reviews automatically and thereby confirmed the usefulness of academic reviews to libraries and readers.

Design/methodology/approach
Firstly, 61,933 academic reviews in Choice: Current Reviews for Academic Libraries were collected with three metadata metrics. Then, review contents were mined to obtain content metrics. Finally, to identify the reliability of academic reviews, Choice review metrics and other assessment metrics for use impact were compared and analysed.

Findings
The analysis results reveal that fine-grained mining of academic reviews can help users quickly understand multi-dimensional features of books, judge or predict the impacts of mass books, so as to provide references for different types of users (e.g. libraries and public readers) in book selection.

Originality/value
Book impact assessment via content mining can provide more detail information for massive users and cover shortcomings of traditional methods. It provides a new perspective and method for researches on use impact assessment. Moreover, this study’s proposed method might also be a means by which to measure other publications besides books.
Sunshine, temperature and wind
Authors: File Dramani J.M. , Derbile Emmanuel Kanchebe 
Published: January 2020

Purpose
This paper aims to draw on community risk assessment (CRA) for assessing vulnerability to climate change in north-western Ghana, focusing on sunshine, temperature and wind, elements of climate which are seldom explored in vulnerability assessments to climate change.

Design/methodology/approach
The paper draws on data collected from a qualitative research design that used participatory rural appraisal methods, particularly, in-depth interviews, focus group discussions and seasonal calendar analysis in three selected rural communities of the Sissala East District. Furthermore, an inter-generational framework was adopted for comparative assessment of vulnerability and changes in vulnerability to climate change.

Findings
The results show that the current generation of smallholder farmers is more vulnerable to climate change than the past generation, the era of grandparents. Thus, farmers are exposed to higher-intensity sunshine, temperature and wind in contemporary times than was the case in the past. Consequently, their livelihoods are affected the most by the damaging effects of these climatic hazards. The CRA process revealed the relevance of indigenous knowledge systems for vulnerability assessments and at the same time, underpins the need for adaptation of such knowledge if it is to sustain smallholder farmer efforts at climate change adaptation at community levels.

Practical implications
The paper recommends an endogenous development approach to climate change adaptation planning (CCAP), one that will build on indigenous knowledge systems for effective community education, mobilization and participatory response to climate change. Policy interventions should aim at enhancing climate change adaptation through innovations in soil and water conservation, access to water for irrigation and domestic use, climate smart-housing architecture and agro-forestry within the framework of decentralization and district development planning.

Originality/value
This paper will contribute to climate change research in two ways: first, by drawing attention to the usefulness of CRA in vulnerability assessment; and second, by focusing on climate elements which are critical for CCAP but rarely given sufficient attention in vulnerability assessments.