bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Association of Body Composition Parameters and Laboratory Markers With The Severity of Hypertriglyceridemia-Induced Pancreatitis
Authors: Chen Lifang , Huang Yingbao , Yu Huajun , Pan Kehua , Zhang Zhao , Man Yi , Hu Dingyuan 
Published: December 2020

Abstract
Background: Hypertriglyceridemia has arisen as the third leading cause of acute pancreatitis. This study aimed at exploring the association between the severity of hypertriglyceridemia-induced pancreatitis (HTGP) and computed tomography (CT)-based body composition parameters and laboratory markers.Methods: Clinical parameters were collected from 242 patients with HTGP between 2017 and 2020. Severity of HTGP was evaluated by original or modified CT severity index. Body composition parameters such as area and radiodensity of muscle, subcutaneous adipose tissue and visceral adipose tissue were calculated by CT at the third lumbar vertebra level. Parameters between mild and moderately severe to severe HTGP were compared. Uni-variate and multi-variate Logistic regression analyses were employed to assess the risk factors of the severity of HTGP.Results: Seventy patients with HTGP (28.9%) were mild. Body mass index, waist circumference and all CT-based body composition parameters differed between male and female patients. None was associated with the severity of HTGP, neither in the male nor in the female. Uni-variate and multi-variate Logistic regression analysis showed that low serum albumin (<35g/L) and high C-reactive protein (>90 mg/L) were risk factors of moderately severe to severe HTGP (P<0.001, OR=4.846, 95%CI=2.122-11.068; P<0.001, OR=4.230, 95%CI=2.050-8.727, respectively). Low serum albumin was also associated with pancreatic necrosis, longer hospital stay and higher scores of APACHE II, Ranson and Marshall in HTGP patients (all P<0.05).Conclusions: Low serum albumin and high C-reactive protein upon admission are associated with the severity of HTGP. However, none of the body composition parameters is associated with the severity of HTGP.
The Association Between Vitamin D and Acute Rejection in Human Kidney Transplantation: A Systematic Review and Meta-analysis Study
Authors: Mirzakhani Mohammad , Mohammadkhani Sheyda , Hekmatirad Shirin , Aghapour Soudabeh , Gorjizadeh Negar , Shahbazi Mehdi , Mohammadnia-Afrouzi Mousa 
Published: December 2020

Abstract

Background: Vitamin D (VitD) deficiency is associated with several diseases such as multiple sclerosis, rheumatoid arthritis, respiratory infection, and so forth. In the field of transplantation (kidney transplantation), some studies reported that patients with VitD deficiency are of increased risk of acute rejection, but other studies did not show such a risk. On the other hand, since VitD is a modulatory factor and can reduce the inflammatory response, understanding the exact role of it in transplantation may contribute to tolerance condition in these patients.Methods: The electronic databases, including PubMed, Scopus, Embase, ProQuest, Web of Science, and Google Scholar, were searched for eligible studies. In general, 14 studies with a total of 4,770 patients were included in this meta-analysis. Regarding the methodological heterogeneity, we selected a random-effects combination model. Moreover, OR was chosen as an effect size for this study.Results: After the combination of 14 studies, we showed that patients in the VitD-deficient group had an 82% increased risk of acute rejection compared with patients in the VitD-sufficient group, and this effect was significant (OR 1.82; 95% confidence interval [CI] [1.29, 2.56]; I2 = 52.3%). This result was significant, and, regarding the narrow CI, it can be a conclusive result. Study quality and gender variables were the main sources of inconsistent results in the primary studies. Moreover, using meta-regression, we showed that VitD deficiency (independent from the estimated glomerular filtration rate (eGFR) of patients) increased the risk of acute rejection.Conclusion: The normal VitD status of patients a few days before and after transplantation can reduce the risk of acute rejection, as it has definite modulatory effects on immune cells.
Genomic Predictions For Fillet Yield And Firmness In Rainbow Trout Using Reduced-Density SNP Panels
Authors: Al-Tobasei Rafet , Ali Ali R. , Garcia Andre L. S. , Lourenco Daniela , Leeds Tim , Salem Mohamed 
Published: December 2020

Abstract
Background One of the most important goals for the rainbow trout aquaculture industry is to improve fillet yield and fillet quality. Previously, we showed that a 50K transcribed-SNP chip can be used to detect quantitative trait loci (QTL) associated with fillet yield and fillet firmness. In this study, data from 1,568 fish genotyped for the 50K transcribed-SNP chip and ~774 fish phenotyped for fillet yield and fillet firmness were used in a single-step genomic BLUP (ssGBLUP) model to compute the genomic estimated breeding values (GEBV). In addition, pedigree-based best linear unbiased prediction (PBLUP) was used to calculate traditional, family-based estimated breeding values (EBV). Results The genomic predictions outperformed the traditional EBV by 35% for fillet yield and 42% for fillet firmness. The predictive ability for fillet yield and fillet firmness was 0.19 - 0.20 with PBLUP, and 0.27 with ssGBLUP. Additionally, reducing SNP panel densities indicated that using 500 – 800 SNPs in genomic predictions still provides predictive abilities higher than PBLUP. Conclusion These results suggest that genomic evaluation is a feasible strategy to identify and select fish with superior genetic merit within rainbow trout families, even with low-density SNP panels.
Effects of Exogenous Adiponectin Supplementation in Early Pregnant PCOS Mice on the Metabolic Syndrome of Adult Female Offspring
Authors: Zuo Meng , Liao Guotao , Zhang Wenqian , Xu Dan , Lu Juan , Tang Manhong , Yan Yue , Hong Chenghao , Wang Yuxia 
Published: December 2020

Abstract
Objective: PCOS is a heterogeneous endocrine disorder with both reproductive and metabolic abnormalities. At present, PCOS has been confirmed to have a certain genetic background. Compared with healthy women, the vast majority of PCOS patients have hyperandrogenemia, and this excessive androgen exposure during pregnancy may affect the development of female fetuses. The aim of the current study was to investigate the effect of adiponectin intervention during early pregnancy of obese mice with PCOS on the metabolic phenotype of adult female offspring.Methods: After the PCOS model was established, C57BL/6J mice were divided into maternal-control, maternal-PCOS, and maternal-PCOS+APN groups. DHEA-induced PCOS mice were supplemented with adiponectin (10 mg/kg/day) in the early pregnancy in order to eliminate adverse hormone exposure and then traced for endocrine indicators in their adult female offspring, which were observed for metabolism syndrome or endocrine disturbance and exhibited the main effects of APN. To further explore the underlying mechanism, the relative expressions of phosphorylated AMPK, PI3K, and Akt were detected in the ovaries of offspring mice.Results: The serum testosterone level of the maternal-PCOS+APN group in early pregnancy was significantly lower than that of the maternal-PCOS group (p < 0.01). The serum testosterone level in the offspring-PCOS+APN group was significantly lower than in the offspring-PCOS group (p＜0.05), the diestrus time characterized by massive granulocyte aggregation in the estrus cycle was significantly shorter than in the offspring-PCOS group (p＜0.05), and the phenotypes of PCOS-like reproductive disorders and metabolic disorders, such as obesity, insulin resistance, impaired glucose tolerance, and hyperlipidemia, were also significantly improved in the offspring-PCOS+APN group (p＜0.05). Compared with the control group, the expression levels of phosphorylated AMPK, PI3K, and Akt in the offspring-PCOS group were significantly decreased (p＜0.05), while those in the offspring-PCOS+APN group were significantly increased (p＜0.05).Conclusions: APN intervention in early pregnancy significantly reduced the adverse effects of maternal obesity and high androgen levels during pregnancy on female offspring and corrected the PCOS-like endocrine phenotype and metabolic disorders of adult female offspring. This effect may be caused by the activation of the AMPK/PI3K-Akt signaling pathway in PCOS offspring mice.
Design of Running Training Assistance System Based on Blockchain Technology in Wireless Network
Authors: Ma Fuxing 
Published: December 2020

Abstract
Running exercise can increase the basal metabolic rate and increase the time of aerobic exercise. Based on the current needs of the general public for running auxiliary training, this paper combines wireless sensing and blockchain technology in the design scheme, and designs and implements a running training auxiliary technology. First, it obtains the user's gait information and other related parameters in the process through the wireless sensor network, and optimize the calculation gait in different states through the noise processing algorithm. Then, we use the blockchain technology to design a data transmission and storage plan for the protection and analysis of the user's personal privacy data. The proposed method builds a new type of sports training assistance system for the masses of modern society and contributes to the masses' physical exercise.
Genetic diversity analysis of brown marmorated stink bug, Halyomorpha halys based on mitochondrial COI and COII haplotypes
Authors: Yan Juncong , Pal Chandan , Anderson Diane , Vétek Gábor , Farkas Péter , Burne Allan , Fan Qing-Hai , Zhang Jinping , Gunawardana Disna N. , Balan Rebijith Kayattukandy , George Sherly , Li Dongmei 
Published: December 2020

Abstract
Background: In the past decade, the brown marmorated stink bug (BMSB), Halyomorpha halys (Hemiptera: Pentatomidae) has caused extensive damage to global agriculture. As a high-risk pest for many countries, including New Zealand, it is important to explore its genetic diversity to enhance our knowledge and devise management strategies for BMSB populations. In this study, two mitochondrial genes, Cytochrome c oxidase I (COI) and Cytochrome c oxidase II (COII) were used to explore the genetic diversity among 463 BMSB individuals collected from 12 countries. Result: In total, 51 COI and 29 COII haplotypes of BMSB were found, which formed 59 combined haplotypes (5 reported and 54 novel). Of these, H1h1 was the predominant haplotype. The haplotype diversity ( Hd ) and nucleotide diversity ( π ) were high while the neutrality (Fu's Fs) values were negative for the BMSB populations in the native countries, China, and Japan. For the BMSB populations from the invaded countries, the Fu's Fs values were negative for populations from Chile, Georgia, Hungary, Italy, Romania, Turkey, and USA, indicating that those populations are under demographic expansion. In comparison, the Fu's Fs values were positive for the populations from Austria, Serbia, and Slovenia, revealing a potential population bottleneck. Analysis of molecular variance (AMOVA) suggested that significant genetic difference exists among the BMSB populations from China, Japan, and the invasive countries. Conclusion: This study revealed that the haplotype diversity of the BMSB populations was high in those two studied countries where BMSB is native to (China and Japan) but low in those countries which have been invaded by the species. The analysis indicated that multiple invasions of BMSB occurred in Europe and the USA. The study also revealed three ancestral lines and most of the novel haplotypes were evolved from them. Moreover, we observed two genetic clusters in the invasive populations that are formed during different invasion events. Our study provided a comprehensive overview on the global haplotypes distribution thus expanding the existing knowledge on BMSB genetic diversity that potentially could play an important role in formulating feasible pest management strategies.
Prognostic factors of time to first abortion after sexual debut among fragile State Congolese women: a survival analysis
Authors: Ekholuenetale Michael , Ekholuenetale Charity Ehimwenma , Barrow Amadou 
Published: December 2020

Abstract

Background: Despite the common restrictive abortion laws, abortion remains widespread in sub-Saharan Africa (SSA) countries. Women still utilize abortion services and put their lives and health at risk because abortion can only be procured illegally in private facilities such as mid-level or small patent medicine store that may be manned by unskilled providers or through a non-medicated approach. The objective of this study was to determine median years and factors of time to first abortion after sexual debut among Congolese women.Methods: We used data from the most recent Republic of Congo Demographic and Health Survey (DHS). A total sample of 3,622 women aged 15-49 years was analyzed. We estimated the overall prevalence of abortion and median years to first abortion. Furthermore, we examined the factors of time to first abortion after sexual debut using multivariable Cox regression and reported the estimates using adjusted Hazard Ratio (aHR) and 95% confidence intervals (CI). Statistical significance was determined at p<0.05.Results: The prevalence of abortion was 60.0% and median years of time to first abortion after sexual debut was 9.0. The prominent reasons for abortion were due to too short birth interval (23.8%), lack of money (21.0%) and that husband/partner did not need a child at that time (14.0%). Women’s age and region were notable factors in timing to first abortion. Furthermore, women from poorer, middle, richer and richest households had 34%, 67%, 86% and 94% higher risk of abortion respectively, when compared with women from poorest households (aHR estimates). Women currently in union/living with a man and formerly in union had 41% and 29% reduction in the risk of abortion respectively, when compared with those never in union (aHR estimates). In addition, women with primary and secondary+ education had 42% and 76% higher risk of abortion respectively, when compared with women with no formal education (aHR estimates). Conclusion: There was high prevalence of abortion with short years at first abortion. Abortion was associated with women’s characteristics. There is need for unwanted pregnancy prevention intervention and the improvement in pregnancy care to reduce adverse pregnancy outcomes among women.
Dendritic cell responses to&nbsp;Plasmodium falciparum&nbsp;in a malaria-endemic setting
Authors: Turner Triniti C. , Arama Charles , Ongoiba Aissata , Doumbo Safiatou , Doumtabé Didier , Kayentao Kassoum , Skinner Jeff , Li Shanping , Traore Boubacar , Crompton Peter D. , Götz Anton 
Published: December 2020

Abstract
Background Plasmodium falciparum causes the majority of malaria cases worldwide and children in sub-Saharan Africa are the most vulnerable group affected. Non-sterile clinical immunity that protects from symptoms develops slowly and is relatively short-lived. Moreover, current malaria vaccine candidates fail to induce durable high-level protection in endemic settings, possibly due to the immunomodulatory effects of the malaria parasite itself. Because dendritic cells play a crucial role in initiating immune responses, the aim of this study was to better understand the impact of cumulative malaria exposure as well as concurrent P. falciparum infection on dendritic cell phenotype and function.Methods In this cross-sectional study, the phenotype and function of dendritic cells freshly isolated from peripheral blood samples of Malian adults with a lifelong history of malaria exposure who were either uninfected (n=27) or asymptomatically infected with P. falciparum (n=8) was assessed. Additionally, plasma cytokine and chemokine levels were measured in these adults and in Malian children (n=19) with acute symptomatic malaria.Results With the exception of lower plasmacytoid dendritic cell frequencies in asymptomatically infected Malian adults, peripheral blood dendritic cell subset frequencies and HLA-DR surface expression did not differ by infection status. Peripheral blood myeloid dendritic cells of uninfected Malian adults responded to in vitro stimulation with P. falciparum blood-stage parasites by up-regulating the costimulatory molecules HLA-DR, CD80, CD86 and CD40 and secreting IL-10, CXCL9 and CXCL10. In contrast, myeloid dendritic cells of asymptomatically infected Malian adults exhibited no significant responses above the uninfected red blood cell control. IL-10 and CXCL9 plasma levels were elevated in both asymptomatic adults and children with acute malaria.Conclusions The findings of this study indicate that myeloid dendritic cells of uninfected adults with a lifelong history of malaria exposure are able to up-regulate co-stimulatory molecules and produce cytokines. Whether mDCs of malaria-exposed individuals are efficient antigen-presenting cells capable of mounting an appropriate immune response remains to be determined. The data also highlights IL-10 and CXCL9 as important factors in both asymptomatic and acute malaria and add to the understanding of asymptomatic P. falciparum infections in malaria-endemic areas.
Biodiversità delle Aleocharinae della Cina: Placusini, Homalotini, Bolitocharini, Eusteniamorphini e Falagriini1 (Coleoptera, Staphylinidae).
Authors: Pace Roberto 
Published: December 2020

In der vorliegenden Arbeit werden 33 Arten aufgelistet. Davon werden 14 Arten sowie eine Gattung als neu für die Wissenschaft beschrieben und abgebildet: eine Art der Gattung Placusa (P. shimianensis n. sp.), drei der Gattung Coenonica (C. guanxiensis n. sp., C. confundibilis n. sp., C. anteopaca n. sp.), eine der Gattung Stenomastax (S. chinensis n. sp.), eine der neuen Gattung Tibetusina n. gen. (T. wolongensis n. sp.), zwei der Gattung Pseudatheta (P. similis n. sp., P. chinensis n. sp.), eine der Gattung Phymatura (P. sinica n. sp.), eine der Gattung Bolitochara (B. sinica n. sp.), eine der Gattung Eusteniamorpha (E. jiajinensis n. sp.) und drei der Gattung Falagria (F. shimianensis n. sp., F. hubeiensis n. sp., F. magnifica n. sp.).SommarioNel presente lavoro sono elencate 33 specie, 14 delle quali sono descritte e illustrate come nuove per la Scienza, una del genere Placusa (P. shimianensis n. sp.), tre del genere Coenonica (C. guanxiensis n. sp., C. confundibilis n. sp., C. anteopaca n. sp.), una del genere Stenomastax (S. chinensis n. sp.), una del nuovo genere Tibetusina (T. wolongensis n. sp.), due del genere Pseudatheta (P. similis n. sp., P. chinensis n. sp.), una del genere Phymatura (P. sinica n. sp.), una del genere Bolitochara (B. sinica n. sp.), una del genere Eusteniamorpha (E. jiajinensis n. sp.) e tre del genere Falagria (F. shimianensis n. sp., F. hubeiensis n. sp., F. magnifica n. sp.).Nomenklatorische Handlungensinica Pace, 2010 (Bolitochara), spec. nov.anteopaca Pace, 2010 (Coenonica), spec. nov.confundibilis Pace, 2010 (Coenonica), spec. nov.guanxiensis Pace, 2010 (Coenonica), spec. nov.jiajinensis Pace, 2010 (Eusteniamorpha), spec. nov.hubeiensis Pace, 2010 (Falagria (Leptagria)), spec. nov.shimianensis Pace, 2010 (Falagria (Leptagria)), spec. nov.magnifica Pace, 2010 (Falagria (Myrmecocephalus)), spec. nov.sinica Pace, 2010 (Phymatura), spec. nov.shimianensis Pace, 2010 (Placusa), spec. nov.chinensis Pace, 2010 (Pseudatheta), spec. nov.gonggaensis (Pace, 1998) (Pseudatheta), comb. nov. hitherto Phymatura gonggaensis Pace, 1998similis Pace, 2010 (Pseudatheta), spec. nov.Tibetusina Pace, 2010 (Staphylinidae), gen. nov.chinensis Pace, 2010 (Stenomastax), spec. nov.wolongensis Pace, 2010 (Tibetusina), spec. nov.
The Neotropical species of the genus Eleusis Laporte, 1835 with description of the new genus Eleusima (Coleoptera: Staphylinidae: Osoriinae)
Authors: Irmler Ulrich 
Published: December 2020

According to Herman (2001) 24 species of the genus Eleusis were known from the Neotropical region before this study. Among these, the following 11 species are newly synonymised: E. cephalotes Bernhauer, 1904, and E. puncticeps Bernhauer, 1921 are synonyms to E. bicolor (Erichson, 1840); E. dubius (Sharp, 1876), Eleusis infima Sharp, 1887, E. marginicollis Bernhauer, 1921, E. armuellensis Bierig, 1931 are synonyms to E. nigerrima Fauvel, 1864; E. pallidipennis (Fauvel, 1864), E. corvina Sharp, 1887, E. flavipennis Sharp, 1887, and E. darlingtoni Blackwelder, 1943 are synonyms to E. interrupta (Erichson, 1840); E. mixta Sharp, 1887 is synonym to E. sctia Sharp, 1887. The new genus Eleusima is described with the new species E. platysoma spec. nov. The following new species of the genus Eleusis are described: E. genieri spec. nov., E. castanea spec. nov., E. rufipennis spec. nov., E. ecuadoriensis spec. nov., E. andina spec. nov., E. boliviana spec. nov., E. hondurana spec. nov., E. nigrita spec. nov., E. elongate spec. nov., E. panamaensis spec. nov., E. peruviana spec. nov., E. struyvei spec. nov., and E. tenuis (Fauvel, 1864), formerly synonymised with E. humilis, was found to be a distinct species and named here E. fauveli spec. nov., E. indica Kraatz, 1859, also synonymised with E. humilis (Erichson, 1840) is a distinct species as well, but not part of the Neotropical fauna. Overall, 24 Eleusis species are now known from the Neotropical region which can be separated into 3 species groups.
Nomenclatural Acts

Eleusima – urn:lsid:zoobank.org:act:8E861E42-9378-477C-BD35-1B6D0697B867
Eleusima platysoma spec. nov. – urn:lsid:zoobank.org:act:CCD6DF2B-5665-41ED-A2BA-55ED02C72A23
Eleusis andina spec. nov. – urn:lsid:zoobank.org:act:23436043-BE8A-46AE-97E5-15BDAEECF02A
Eleusis boliviana spec. nov. – urn:lsid:zoobank.org:act:63DF628A-E08F-4D9E-9518-B5C00599B8D8
Eleusis castanea spec. nov. – urn:lsid:zoobank.org:act:3121AA37-99A7-4839-9172-A2A98F9E5372
Eleusis ecuadoriensis spec. nov. – urn:lsid:zoobank.org:act:774F9A2D-25FE-426C-8A32-C52AB801876B
Eleusis elongate spec. nov. – urn:lsid:zoobank.org:act:FD5048E3-6760-43B9-BB13-D5FC480530A1
Eleusis fauveli spec. nov. – urn:lsid:zoobank.org:act:2C9C2952-39B3-4ECE-B7A9-CDE2E37B1E3E
Eleusis genieri spec. nov. – urn:lsid:zoobank.org:act:BAA0CF84-6884-461A-877A-44CA8B6B544A
Eleusis hondurana spec. nov. – urn:lsid:zoobank.org:act:BB492AC3-EF93-4F93-90E5-FD266A957102
Eleusis nigrita spec. nov. – urn:lsid:zoobank.org:act:7786C482-50D4-419D-85FB-FB349801FD11
Eleusis panamaensis spec. nov. – urn:lsid:zoobank.org:act:7078364E-083E-4BC7-ADE2-045789D19FFA
Eleusis peruviana spec. nov. – urn:lsid:zoobank.org:act:819FB601-081E-4EEF-BAD3-2363C6D299CF
Eleusis rufipennis spec. nov. – urn:lsid:zoobank.org:act:B6989833-5DD4-492E-969F-DD1F4E6E97E9
Eleusis struyvei spec. nov. – urn:lsid:zoobank.org:act:0BB5EBEE-6C8F-49D9-9D90-7178E660227F