bluuebunny/crossref_metadata_2025_split huggingface dataset:
Galaxy cluster mass estimation with deep learning and hydrodynamical simulations
Authors: Yan Z , Mead A J , Van Waerbeke L , Hinshaw G , McCarthy I G 
Published: September 2020

ABSTRACT
We evaluate the ability of convolutional neural networks (CNNs) to predict galaxy cluster masses in the BAHAMAS hydrodynamical simulations. We train four separate single-channel networks using: stellar mass, soft X-ray flux, bolometric X-ray flux, and the Compton y parameter as observational tracers, respectively. Our training set consists of ∼4800 synthetic cluster images generated from the simulation, while an additional ∼3200 images form a validation set and a test set, each with 1600 images. In order to mimic real observation, these images also contain uncorrelated structures located within 50 Mpc in front and behind clusters and seen in projection, as well as instrumental systematics including noise and smoothing. In addition to CNNs for all the four observables, we also train a ‘multichannel’ CNN by combining the four observational tracers. The learning curves of all the five CNNs converge within 1000 epochs. The resulting predictions are especially precise for halo masses in the range $10^{13.25}\, \mathrm{M}_{\odot }\lt M\lt 10^{14.5}\, \mathrm{M}_{\odot }$, where all five networks produce mean mass biases of order ≈1 per cent with a scatter of ≲20 per cent. The network trained with Compton y parameter maps yields the most precise predictions. We interpret the network’s behaviour using two diagnostic tests to determine which features are used to predict cluster mass. The CNNs trained with stellar mass images detect galaxies (not surprisingly), while CNNs trained with gas-based tracers utilize the shape of the signal to estimate cluster mass.
Spectral and imaging properties of Sgr A* from high-resolution 3D GRMHD simulations with radiative cooling
Authors: Yoon D , Chatterjee K , Markoff S B , van Eijnatten D , Younsi Z , Liska M , Tchekhovskoy A 
Published: September 2020

ABSTRACT
The candidate supermassive black hole in the Galactic Centre, Sagittarius A* (Sgr A*), is known to be fed by a radiatively inefficient accretion flow (RIAF), inferred by its low accretion rate. Consequently, radiative cooling has in general been overlooked in the study of Sgr A*. However, the radiative properties of the plasma in RIAFs are poorly understood. In this work, using full 3D general–relativistic magnetohydrodynamical simulations, we study the impact of radiative cooling on the dynamical evolution of the accreting plasma, presenting spectral energy distributions and synthetic sub-millimetre images generated from the accretion flow around Sgr A*. These simulations solve the approximated equations for radiative cooling processes self-consistently, including synchrotron, bremsstrahlung, and inverse Compton processes. We find that radiative cooling plays an increasingly important role in the dynamics of the accretion flow as the accretion rate increases: the mid-plane density grows and the infalling gas is less turbulent as cooling becomes stronger. The changes in the dynamical evolution become important when the accretion rate is larger than $10^{-8}\, M_{\odot }~{\rm yr}^{-1}$ ($\gtrsim 10^{-7} \dot{M}_{\rm Edd}$, where $\dot{M}_{\rm Edd}$ is the Eddington accretion rate). The resulting spectra in the cooled models also differ from those in the non-cooled models: the overall flux, including the peak values at the sub-mm and the far-UV, is slightly lower as a consequence of a decrease in the electron temperature. Our results suggest that radiative cooling should be carefully taken into account in modelling Sgr A* and other low-luminosity active galactic nuclei that have a mass accretion rate of $\dot{M} \gt 10^{-7}\, \dot{M}_{\rm Edd}$.
A pilot search for extragalactic OH absorption with FAST
Authors: Zheng Zheng , Li Di , Sadler Elaine M , Allison James R , Tang Ningyu 
Published: September 2020

ABSTRACT
OH absorption is currently the only viable way to detect OH molecules in non-masing galaxies at cosmological distances. There have been only six such detections at z &gt; 0.05 to date and so it is hard to put a statistically robust constraint on OH column densities in distant galaxies. We carried out a pilot OH absorption survey towards eight associated and one intervening H i 21-cm absorbers using the Five-hundred-meter Aperture Spherical radio Telescope (FAST). We were able to constrain the OH abundance relative to H i ([OH]/[H i]) to be lower than 10−6 ∼ 10−8 for redshifts z∈ [0.1919, 0.2241]. Although no individual detection was made, stacking three associated absorbers free of RFI provides a sensitive OH column density 3σ upper-limit $\sim 1.57 \times 10^{14} (T_x^{\rm OH}/10\,\mathrm{ K})(1/f_\mathrm{ c}^{\rm OH})\mathrm{ cm}^{-2}$, which corresponds to a [OH]/[H i] &lt; 5.45 × 10−8. Combining with archival data, we show that associated absorbers have a slightly lower OH abundance than intervening absorbers. Our results are consistent with a trend of decreasing OH abundance with decreasing redshift.
Genomic Targets of Positive Selection in Giant Mice from Gough Island
Authors: Payseur Bret A , Jing Peicheng 
Published: September 2020

AbstractA key challenge in understanding how organisms adapt to their environments is to identify the mutations and genes that make it possible. By comparing patterns of sequence variation to neutral predictions across genomes, the targets of positive selection can be located. We applied this logic to house mice that invaded Gough Island (GI), an unusual population that shows phenotypic and ecological hallmarks of selection. We used massively parallel short-read sequencing to survey the genomes of 14 GI mice. We computed a set of summary statistics to capture diverse aspects of variation across these genome sequences, used approximate Bayesian computation to reconstruct a null demographic model, and then applied machine learning to estimate the posterior probability of positive selection in each region of the genome. Using a conservative threshold, 1,463 5-kb windows show strong evidence for positive selection in GI mice but not in a mainland reference population of German mice. Disproportionate shares of these selection windows contain genes that harbor derived nonsynonymous mutations with large frequency differences. Over-represented gene ontologies in selection windows emphasize neurological themes. Inspection of genomic regions harboring many selection windows with high posterior probabilities pointed to genes with known effects on exploratory behavior and body size as potential targets. Some genes in these regions contain candidate adaptive variants, including missense mutations and/or putative regulatory mutations. Our results provide a genomic portrait of adaptation to island conditions and position GI mice as a powerful system for understanding the genetic component of natural selection.
Steroids as treatment for glomerulonephritis: time for a rethink
Authors: Hendra Heidy , Salama Alan D 
Published: September 2020

Abstract
Glucocorticoids have been a cornerstone of treatment for inflammatory and autoimmune kidney diseases for almost 70 years, yet it is fair to say, we still do not know how ‘best’ to use them. Significant adverse events are associated with their continued use, which contribute to premature patient mortality. Steroid avoidance or minimization is possible and has been tested in various glomerular diseases, as a result of novel agents or innovative regimens using established therapeutics. It is now time to seriously address our use of steroids and educate physicians on better ways of managing inflammatory kidney diseases.
Bank of Japan Equity Purchases: The (Non-)Effects of Extreme Quantitative Easing*
Authors: Charoenwong Ben , Morck Randall , Wiwattanakantang Yupana 
Published: September 2020

Abstract
From January 2011 through March 2018, the Bank of Japan purchased equity index exchange-traded funds (ETFs) worth about 3.5% of GDP. Identification of the effect of central bank ETF purchases on stock valuations and corporate responses is via differently-weighted and changing stock indices. BOJ purchases lift valuations, increase share issuances, and increase total assets. On average, the latter increase is due to cash and short-term securities rather than capital investment. However, firms with worse corporate governance do increase capital investment. These findings suggest central bank equity purchases are a problematic tool for stimulating economic growth through high broad-based private-sector corporate investment.
EVALUATION OF NEUTRON AMBIENT DOSE EQUIVALENT IN CARBON-ION RADIOTHERAPY WITH ENERGY SCANNING
Authors: Matsumoto Shinnosuke , Yonai Shunsuke 
Published: September 2020

Abstract
In carbon-ion radiotherapy (CIRT), secondary neutrons are produced by nuclear interactions in the beamline devices or patient. Herein, the characteristics of secondary neutrons in CIRT with energy scanning (ES) were evaluated. Neutron ambient dose equivalents (H*(10)) were measured using WENDI-II. The neutron energy spectrum was calculated using the Monte Carlo simulation. Measurement and calculation were performed under realistic case scenarios using maximum beam energies (Emax) of 290, 350 and 400 MeV u −1. Moreover, H*(10) in ES was compared with H*(10) in range-shifter scanning (RS) and hybrid scanning (HS). H*(10) in Emax = 290 MeV u−1 was 65% less than that in Emax = 400 MeV u−1. At Emax = 350 MeV u−1, H*(10) in ES at θ = 120 was 42% of that at θ = 60. The neutron dose in ES CIRT decreased to approximately 60 and 70% of that in RS and HS CIRT, respectively, at 50-cm distance from the beam axis.
THE EFFICACY OF RADPAD AS A RADIATION PROTECTION TOOL IN CT FLUOROSCOPY GUIDED LUNG BIOPSIES
Authors: Lawson Michael , Kuganesan Ahilan , Parry Georgia , Badawy Mohamed Khaldoun 
Published: September 2020

Abstract
Computed tomography fluoroscopy is now the preferred technique for percutaneous lung biopsies. However, concern regarding operator and patient radiation dose remains, which warrants further exploration into dose optimisation tools. This phantom-study aims to assess the dose reduction capabilities of RADPAD, a single-use patient drape designed to decrease staff exposure to scattered radiation. Dosemeters at the waist and eye levels were used to determine the whole-body and lens exposure during simulated lung biopsy procedures while using RADPAD and other combinations of personal protective equipment. RADPAD resulted in a 36% and 38% dose reduction for whole-body and eye exposure, respectively. However, when used in combination with radioprotective eyewear and aprons, RADPAD did not reduce the radiation dose further. Consequently, the use of standard personal protective equipment is a more cost-effective option for staff dose reduction. RADPAD is useful in the reduction of radiation dose to unprotected regions.
Social and affective neuroscience: an Australian perspective
Authors: Kumfor Fiona , Tracy Lincoln M , Wei Grace , Chen Yu , Domínguez D. Juan F , Whittle Sarah , Wearne Travis , Kelly Michelle 
Published: September 2020

Abtract
While research in social and affective neuroscience has a long history, it is only in the last few decades that it has been truly established as an independent field of investigation. In the Australian region, despite having an even shorter history, this field of research is experiencing a dramatic rise. In this review, we present recent findings from a survey conducted on behalf of the Australasian Society for Social and Affective Neuroscience (AS4SAN) and from an analysis of the field to highlight contributions and strengths from our region (with a focus on Australia). Our results demonstrate that researchers in this field draw on a broad range of techniques, with the most common being behavioural experiments and neuropsychological assessment, as well as structural and functional magnetic resonance imaging. The Australian region has a particular strength in clinically driven research, evidenced by the types of populations under investigation, top cited papers from the region, and funding sources. We propose that the Australian region has potential to contribute to cross-cultural research and facilitating data sharing, and that improved links with international leaders will continue to strengthen this burgeoning field.
Right-Wing Stewards: The Promoting Effect of Religiosity on Environmental Concern among Political Conservatives in a Global Context
Authors: Hekmatpour Peyman 
Published: September 2020

AbstractThis article studies the relationship between individuals’ religiosity, political ideology, and environmental concern, in a cross-national setting. Drawing data from multiple waves of the World Values Survey (1999–2009), the final sample of this study includes 44,391 respondents nested in 43 countries. By using a multi-level modeling technique, the study finds that religiosity is positively associated with respondents’ environmental concerns in terms of willingness to pay for the environment, agreement with increased taxes to prevent environmental pollution, and choosing environmental protection over economic interests. Political ideology, measured via individuals’ self-placement on a left-right continuum, does not have a meaningful relationship with environmental concern in a global setting. Nevertheless, there is an interaction effect between religiosity and political ideology. Increased religiosity, particularly among more conservative individuals, is associated with a higher probability of environmental concern. Comparatively, religiosity virtually does not affect liberals’ concern for the natural environment. The gap between liberals and conservatives regarding the natural environment is more pronounced at lower levels of religiosity; as religiosity increases, the gap starts to narrow. Results suggest that religion has the potential to elevate some of the political barriers on the way towards reaching a collective environmental consciousness.
Dengue and post-infection fatigue: findings from a prospective cohort—the Colombo Dengue Study
Authors: Sigera Ponsuge C , Rajapakse Senaka , Weeratunga Praveen , De Silva Nipun L , Gomes Laksiri , Malavige Gathsaurie N , Rodrigo Chaturaka , Fernando Sumadhya D 
Published: September 2020

AbstractBackgroundPrevious studies on post-infection fatigue in dengue are few but suggest that up to 25% of dengue patients may suffer from fatigue. This study aimed to evaluate the prevalence and associations of post-infection fatigue in dengue patients compared with non-dengue fever patients.MethodsPost-infection fatigue and its demographic and clinical associations were assessed in adult dengue and non-dengue fever patients 2 months after the acute infection in a prospective cohort study in Sri Lanka. Fatigue at 2 months (primary endpoint) was assessed with the fatigue questionnaire as a dichotomous outcome based on a pre-recommended cut-off (score ≥4) and as the total score from the questionnaire (higher score indicates more fatigue).ResultsOf 260 patients, 158 had dengue and, of these, 51 (32%) had fatigue at 2 months. Risk was higher in dengue patients (vs non-dengue; relative risk [RR] 4.93 [95% confidence interval {CI} 2.3 to 10.4]) and more so in female dengue patients (vs male dengue patients; RR 2.45 [95% CI 1.24 to 4.86]). Severe dengue patients had a higher mean fatigue score (p=0.024).ConclusionsPost-infection fatigue is an underappreciated burden of this widely prevalent infection. Our findings are useful to triage patients at risk of fatigue for follow-up.
Pills to Powder: A 17-Year Transition From Prescription Opioids to Heroin Among US Adolescents Followed Into Adulthood
Authors: McCabe Sean Esteban , Boyd Carol J. , Evans-Polce Rebecca J. , McCabe Vita V. , Schulenberg John E. , Veliz Philip T. 
Published: September 2020

Objectives:
To examine the longitudinal relationships between US adolescents’ prescription opioid use and misuse and any subsequent heroin use in adulthood.

Methods:
Nationally representative samples of adolescents from 25 independent cohorts were surveyed via self-administered questionnaires and followed from ages 18 to 35 (n = 11,012). Adolescents were divided into 5 subgroups based on survey responses at age 18: no lifetime exposure to prescription opioids (population controls), medical prescription opioid use without a history of nonmedical misuse (medical use only), medical use followed by nonmedical misuse, nonmedical misuse followed by medical use, and nonmedical misuse only. These 5 subgroups were compared on their risk for any heroin use through age 35 (1993–2017). Adolescents who reported lifetime heroin use at age 18 were excluded.

Results:
Adolescents who reported nonmedical prescription opioid misuse followed by medical use or nonmedical misuse only had greater odds of any heroin use in adulthood than population controls. More recent cohorts of adolescents who reported nonmedical misuse or medical use only (compared to older cohorts) had greater odds of any heroin use in adulthood relative to population controls. Nearly 1 in 3 adolescents in recent cohorts who reported nonmedical prescription opioid misuse transitioned to any heroin use.

Conclusions:
There is increased risk for heroin use among adolescents who initiated nonmedical misuse or adolescents prescribed opioids in more recent cohorts. These findings indicate historical variation and reinforce the critical role of vigilant monitoring and drug screening to detect high-risk individuals who would benefit from an intervention to reduce later heroin use.
The Influence of Selective Serotonin Reuptake Inhibitors on Lumbar Arthrodesis
Authors: Pirkle Sean , Bhattacharjee Sarah , El Dafrawy Mostafa , Leucht Philipp , Shi Lewis L. , Lee Michael J. 
Published: September 2020

Study Design:
Retrospective analysis using the PearlDiver national insurance claims database.

Objective:
To investigate the relationship between chronic preoperative selective serotonin reuptake inhibitor (SSRI) prescriptions and nonunion following spine fusion surgery.

Summary of Background Data:
Contemporary literature has linked SSRIs to decreased bone mineral density and increased rates of future bone fracture. Furthermore, a recent murine model has suggested a potential role in the quality of fracture healing itself.

Methods:
All single-level lumbar fusion patients were identified. The rate of nonunion diagnosis between 6 and 24 months following surgery was assessed. A stratified analysis of chronic SSRI use and a number of comorbidities was conducted, followed by a multiple logistic regression analysis of nonunion accounting for qualifying risk factors. Finally, subanalyses of individual procedure codes were carried out.

Results:
In total, 7905 single-level lumbar fusion patients were included. In the multivariate analysis, chronic SSRI [odds ratio (OR): 1.558, P=0.004] and tobacco use (OR: 1.500, P=0.011) were identified as independent risk factors for nonunion, whereas patient age over 60 years (OR: 0.468, P<0.001) was observed to be negatively associated with nonunion. In the individual procedure subanalyses, SSRIs were significantly associated with nonunion in 2 of 3 univariate analyses and observed to be an independent risk factor for nonunion in 2 of the 3 procedure populations.

Conclusions:
These data suggest that patients treated concomitantly for mental health disorders with SSRIs before arthrodesis may be at an increased risk of postoperative nonunion. Closer follow-up may be indicated in this patient population.
Radiation Exposure to Scrub Nurse, Assistant Surgeon, and Anesthetist in Minimally Invasive Spinal Fusion Surgery Comparing 2D Conventional Fluoroscopy With 3D Fluoroscopy-based Navigation
Authors: Klingler Jan-Helge , Scholz Christoph , Hohenhaus Marc , Volz Florian , Naseri Yashar , Krüger Marie T. , Vasilikos Ioannis , Roelz Roland , Brönner Johannes , Hoedlmoser Herbert , Sircar Ronen , Hubbe Ulrich 
Published: September 2020

Study Design:
A randomized controlled trial.

Objective:
To compare the radiation exposure with the scrub nurse, assistant surgeon, and anesthetist during minimally invasive transforaminal lumbar interbody fusion using conventional 2-dimensional (2D) fluoroscopy or 3D fluoroscopy-based navigation.

Summary of Background Data:
Minimally invasive spinal fusion techniques are related to higher radiation exposures compared with open techniques. Especially the routinely exposed surgical staff faces the risks of increased radiation exposure.

Methods:
In total, 41 patients with planned monosegmental minimally invasive transforaminal lumbar interbody fusion were randomized into the intraoperative imaging techniques 2D fluoroscopy or 3D navigation. Eye lens and film dosemeters were attached to defined locations of the scrub nurse, assistant surgeon, and anesthetist. Mann-Whitney U and Wilcoxon-matched pairs signed-rank test were used to compare dosemeter readings. This study was registered with the German Clinical Trials Register (DRKS00004514).

Results:
The radiation exposure per surgery was low for the scrub nurse, assistant surgeon, and anesthetist in both the 2D fluoroscopy and 3D navigation groups. The maximum average value of 0.057±0.031 mSv was measured on the unprotected chest of the assistant surgeon and was thus slightly above the lower detection limit of the dosemeters (0.044 mSv). The annual occupational dose limit would be exceeded at the earliest after 571 operations for the unprotected eye lens of the assistant surgeon.

Conclusions:
Minimally invasive lumbar fusion surgery is possible with comparatively low radiation exposure to the assisting operating room personnel without exceeding the annual maximum occupational radiation exposure. However, there is no definite dose value below which ionizing radiation poses no risk. Consequently, radiation sparing work routines should be strictly followed.
Electrolyte Beverage Intake to Promote Hydration and Maintain Kidney Function in Guatemalan Sugarcane Workers Laboring in Hot Conditions
Authors: Krisher Lyndsay , Butler-Dawson Jaime , Yoder Hillary , Pilloni Daniel , Dally Miranda , Johnson Evan C. , Jaramillo Diana , Cruz Alex , Asensio Claudia , Newman Lee S. 
Published: September 2020

Objectives:
To evaluate impact of electrolyte supplementation on hydration status and health outcomes in Guatemalan agricultural workers performing heavy work under hot climatic conditions.

Methods:
A 3-week pragmatic trial was conducted with a group of 50 workers during the 2017 to 2018 sugarcane harvest. Workers received an electrolyte hydration intervention during 2 of the 3 weeks. Blood and urine samples were collected each week.

Results:
Increased electrolyte intake resulted in less muscle injury. Kidney function was maintained across the intervention period. Workers were adequately hydrated and average electrolyte levels remained in normal ranges. Mild indications of hyponatremia occurred at higher levels of fluid intake.

Conclusions:
This trial demonstrates the feasibility of maintaining workers’ electrolyte levels under extremely hot and humid conditions while mitigating muscle injury. Electrolyte supplementation should be added to standard workplace water, rest, and shade interventions to protect workers.