bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temperatures limitation of adsorptive solar powered ice maker using AC35-methanol pair
Authors: Cherrad Noureddine 
Published: October 2019

Abstract
A numerical evaluation of temperatures limits of solar adsorption refrigeration machine cycle using the AC35-methanol pair is presented in this paper. The cold production was better for lower adsorption temperatures and higher temperatures of evaporating and generating. For each 1 kg of adsorbent, 1 kg of ice can be produced for temperatures of generating from 40°C to 100°C according to solar irradiance and ambient temperature. The considered lower adsorption temperature is 10°C, which can allow to produce 9 kg of ice for higher temperatures of generating up to 130°C, this needs 680 kJ of solar irradiance for surface area of 1 m2 of solar collector. The considered higher evaporating temperature is 10°C, which can allow to produce 3.5 kg of ice for higher temperatures of generating up to 144°C, this needs 622 kJ of solar irradiance for surface area of 1 m2 of solar collector.
Energy efficiency improvement in hospital buildings, based on the example of a selected type of hospital facility in Poland
Authors: Suszanowicz D , Ratuszny P 
Published: October 2019

Abstract
Energy demand in hospitals is of highly diverse nature: heat energy, cool energy and electricity. A guarantee of energy supply is required to ensure continuity of medical procedures. Taking care of the lowest possible costs of hospital operations, special attention should be paid to energy efficiency of the installations used in the hospital buildings. The paper presents an analysis of energy demand for heating, cooling, ventilation and lighting in an example hospital in Poland. The selected object was considered a reference as it was built according to a repetitive construction plan, according to which several dozen other hospitals were built in Poland. On the basis of data from 2013-2017, a summary of heat, cold and electricity demand for the hospital in its current technical condition was prepared. Concepts of technical and economic modernization of systems using energy in the analysed facility were proposed, assuming different ranges of changes for individual installations in the hospital. After the analysis of various modernization options, a project was proposed combining the use of heat pumps, photovoltaic installations and generation of heat and cooling in trigeneration, all of which allowed to reduce the costs of operation of the hospital energy systems by about 31%.
Identification of the best location for an environmental friendly small hydropower plant
Authors: Moldoveanu A , Popescu D 
Published: October 2019

Abstract
The promotion of renewable energy sources exploitation represents an important goal of the European Union and in this respect the Water Framework Directive was issued. The document requires periodic hydropower assessment of the water courses, using software tools if possible. In this paper a methodology to identify best location for a small hydro power plant is proposed. The methodology is based on two software VADIPRO-ASTE and SMART MINI-IDRO and takes into consideration environmental restrictions. The optimization process uses available monthly average flows in a river section, calculated by taking into consideration the ecological flow and the water consumption for non-electricity production purposes. The ecological flow was calculated by a method elaborated by the National Institute of Hydrology and Water Management, to respect the legislation OUG 78/2017 that supports aquatic ecosystems functionality.
Proposed maintenance system of Gelora Sriwijaya Jakabaring Stadium (case study: lighting utilities)
Authors: Yazuar Muhammad Syazari , Sangadji Senot , Kristiawan Stefanus Adi 
Published: October 2019

Abstract
Maintenance of the stadium has been done for the 18th Asian Games 2018. However, the previous maintenances were not comprehensive and held in the run up to the big events only. It affects the performance of its components utilities. A new local company was established by the Government of South Sumatra Province, in order to make a good maintenance of the stadium. However, the planned maintenance has not been actualized by the company yet. Many obstacles encountered in stadium maintenance, including regulatory, complexity of utilities, and stakeholder’s influences. This paper aims to develop a maintenance system that is in accordance with existing conditions and applicable regulations. This study is devoted to electrical lighting systems because almost every week the stadium is also used for football matches. The methodology was divided into three parts, i.e.: rating for each parts of the utility, descriptive qualitative for regulatory identification, and stakeholders analysis, and they are developed to create a maintenance system. The result is a system that is proposed to find out the most important stakeholders in the maintenance of the highest priority of lighting utility based on official assessment.
Road construction project waste material recommendations
Authors: Waty Mega , Sulistio Hendrik 
Published: October 2019

Abstract
After risk identification and risk analysis done, so risk response is carried out. Risk response is handled by the service provider. Recommendation is the final result of risk management of road construction project waste material. The recommendation is the aggregate B and Ready Mix Concrete is necessary to pay attention to the waiting time and pay attention to the critical trajectory on material scheduling so that breakdowns and scheduling updates are made per week. Need to pay attention to rainfall and implementation methodology. Recommendations for lean concrete waste material are necessary to pay attention to the waiting time and pay attention to the critical trajectory on material scheduling so that breakdowns and scheduling updates are carried out per week. Need to pay attention to rainfall and implementation methodology. And the causes for minimizing waste material must be considered.
Comparison of the RSNI 1726:2018 and the SNI 1726:2012 design response spectra of 17 major cities in Indonesia
Authors: Sutjipto Suradjin , Sumeru Indrawati 
Published: October 2019

Abstract
Based on the 2017 Indonesian Seismic Map and the ASCE 7-16, the proposed Indonesian Seismic Design Code - RSNI 1726:2018, was developed to renew the current SNI 1726:2012 code. Taking a sampling of 17 major cities representing all regions in Indonesia, this paper presents the comparison of the RSNI 1726:2018 and the SNI 1726:2012 design response spectra. All cities located in high seismic areas have an anomaly characteristic, where the design response spectra of site class SE (soft soil) is less than that of site class SD (medium soil), or even less than that of site class SC (hard soil), contrary to what Structural and Geotechnical Engineers think so far, that the design response spectra of site class SE is always higher than that of site classes SD and SC.
Development Precast and Prestressed Concrete Rigid Pavement System in Indonesia
Authors: Nurjaman Hari Nugraha , Faizal Lutfi , Suaryana Nyoman , Dharmawan Yudhi , Wantoro Agus , Purnomo  , Suwito  
Published: October 2019

Abstract
Roadway pavements are important parts of transportation system and thus should be adequately strong and durable. Unfortunately, many pavements constructed in Indonesia fail to reach their design service life. Among major factors contributed to early damages to the pavements in Indonesia are unfulfilled specified pavement construction specifications, traffic overload and poor support condition. As an attempt to produce better pavement system and as part of an accelerated infrastructure program in Indonesia, new precast pavement system using unbonded posttensioned technology that has characteristic of self-centering has recently been developed. This self-centering concrete pavement is expected to reduce the impact of overload and be able to overcome imperfect subbase, subgrade and poor soil condition. The theoretical and experimental development programs of the new concrete rigid pavement system will be described in this paper. The developed pavement system is then implemented to see the effectiveness construction procedures and later on tested using Falling Weight Deflectometer (FWD) method to evaluate its structural performance.
Review study of irregularity track monitoring based on inertial measure unit and power spectral density analysis
Authors: Istiar  , Widyastuti H 
Published: October 2019

Abstract
The maintenance of railway in Indonesia is determined by the track quality index (TQI). Analysed of TQI is based on track geometric inspection data. Currently, track geometric inspection uses a Track Geometric Vehicle (TGV) or Track Recorded Vehicle (TRV). The TRV’s provide accurate geometry measurements. But, it was expensive to run, may disrupt regular train services during their operation, need for occupation of track limit the number of measurement operations undertaken annually and optical sensors are sensitive to the dirt, found in the railway environment. TRV’s data was analysed by statistical function of the standard deviation to determine of TQI. TQI has some disadvantages, for example, it cannot represented the wavelength contents of the geometry defect, which is related to the particular issue in train-track interaction. Therefore, it is necessary to propose effective, efficient and reliable track quality assessment method. This paper will review some irregularity track monitoring methods that were probably used to track monitoring in Indonesia.
Estimation of Vehicle Stops Based on Modified Canadian Capacity Guide Formula Under Non-Lane Based Road Traffic Condition
Authors: Farabi A A 
Published: October 2019

Abstract
Vehicle stops estimation is one of the important parameters to assess the performance of a signalized road intersection. Canadian Capacity Guide provides a formula that can estimate number of vehicles that stops at least once due to the traffic signal. This study reviews the applicability of this formula for non-lane based traffic. The formula is segmented into two periods to check the estimation of stops during red period and green period. It is found that the formula underestimates the number of stops during red period. Also, the formula estimated number of stops is significantly higher during the green period. As traffic operation and vehicle maneuver of non-lane based traffic are much different from lane based disciplined traffic, the formula cannot predict vehicle stops accurately. Therefore, the estimation of vehicle stops by Canadian Capacity Guide formula is found to deviate considerably from field observed number of stops of vehicles. Thus, a modified regression formula is provided that can estimate the number of stops of vehicles for non-lane based traffic operation. The modified formula fits fairly good with the local traffic condition.
Model of queuing in the railway level crossing (case study: Imam Bonjol railway level crossing in Blitar)
Authors: Widyastuti H , Utami A , Dzulfiqar Z M 
Published: October 2019

Abstract
A high number of accidents in railway level crossing causes loss of life and material. Furthermore, the losses are also experienced by users of traffic on the highway such as disturbance in the form of delay which can lead to increase the length of travel time where the vehicle will stop, and give impact to the emergency queue vehicle at railway level crossing. Considering those problems, there has been build two models which are: the first model is the queuing of traffic length and with considering the length and speed of the train, and the second model is the queuing of traffic with considering the gate closing time. The methodology applied was an observation on field and survey data and then calculation from Road Capacity Guidelines of Indonesia (PKJI 2014) and queue length calculation using the queuing analysis method. Data have been collected and analysed by making the model relationship using linear regression method. The result showed that there is a positive relationship between the train lengths with the duration of gate closing time. However, the train speed has a negative relationship. Moreover, the length of the train has a positive relationship with the length of the vehicle queue.
Integrated multimodal disaster mitigation management for urban areas: a preliminary study for 2-d flood modeling
Authors: Prastica R M S , Wicaksono D 
Published: October 2019

Abstract
Flooding in urban areas is a common phenomenon in megacities due to the high population and settlement growth. Lack of knowledge from urban societies triggers them to intervene in the capacity of the river for housing. This impact affects various disasters, both quality and quantity of water. Kali Belik experiences flooding every year, although several solutions have been installed to mitigate, for example, Embung. Integrated multimodal disaster mitigation management is proposed to solve the problems and answer the research gaps. The preliminary research only focuses on flood analysis. The analysis uses 2-D modeling with HEC-RAS. The study concludes that the main factor of flooding in the research area is decreasing river capacity due to social behavior. Further research would be conducted to obtain a comprehensive understanding and solution by involving the government, academics, and society.
Identification of flood risk zones in the region of Yogyakarta
Authors: Nursetiawan  , Faizah R 
Published: October 2019

Abstract
There are three rivers that cross the center of the Yogyakarta region and through Sleman Regency, Yogyakarta City and Bantul District, namely Code River, Gajah Wong River and Winongo River. The contribution of these three rivers to flood events in Yogyakarta is considered significantly high because the river passes through urban areas, settlements, agricultural land, and densely populated areas. In this study a hazard level map and the level of vulnerability of floods are created in those three watersheds. Map making starts with a study of hazards and vulnerabilities using the Analytical Hierarchy Process (AHP) method, weighting, scoring, and continued with a map depiction using Geographic Information Systems (GIS). Map of research results in the form of hazard level maps and flood vulnerability levels for Code watershed, Gajah Wong and Winongo. From the map, it can be concluded that most watershed areas of the Code are included in the level of moderate danger and low level of vulnerability. The entire Gajah Wong watershed is included in a moderate level of danger and most of them are at a high level of vulnerability, while most of the Winongo watershed has a high level of danger and vulnerability.
Age and the distribution of major injury across a national trauma system
Authors: Dixon Jan Robert , Lecky Fiona , Bouamra Omar , Dixon Paul , Wilson Faye , Edwards Antoinette , Eardley Will 
Published: October 2019

Abstract

Background
Trauma places a significant burden on healthcare services, and its management impacts greatly on the injured patient. The demographic of major trauma is changing as the population ages, increasingly unveiling gaps in processes of managing older patients. Key to improving patient care is the ability to characterise current patient distribution.

Objectives
There is no contemporary evidence available to characterise how age impacts on trauma patient distribution at a national level. Through an analysis of the Trauma Audit Research Network (TARN) database, we describe the nature of Major Trauma in England since the configuration of regional trauma networks, with focus on injury distribution, ultimate treating institution and any transfer in-between.

Methods
The TARN database was analysed for all patients presenting from April 2012 to the end of October 2017 in NHS England.

Results
About 307,307 patients were included, of which 63.8% presented directly to a non-specialist hospital (trauma unit (TU)). Fall from standing height in older patients, presenting and largely remaining in TUs, dominates the English trauma caseload. Contrary to perception, major trauma patients currently are being cared for in both specialist (major trauma centres (MTCs)) and non-specialist (TU) hospitals. Paediatric trauma accounts for &lt;5% of trauma cases and is focussed on paediatric MTCs.

Conclusions
Within adult major trauma patients in England, mechanism of injury is dominated by low level falls, particularly in older people. These patients are predominately cared for in TUs. This work illustrates the reality of current care pathways for major trauma patients in England in the recently configured regional trauma networks.
Decoding the relationship between ageing and amyotrophic lateral sclerosis: a cellular perspective
Authors: Pandya Virenkumar A , Patani Rickie 
Published: October 2019

Abstract
With an ageing population comes an inevitable increase in the prevalence of age-associated neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), a relentlessly progressive and universally fatal disease characterized by the degeneration of upper and lower motor neurons within the brain and spinal cord. Indeed, the physiological process of ageing causes a variety of molecular and cellular phenotypes. With dysfunction at the neuromuscular junction implicated as a key pathological mechanism in ALS, and each lower motor unit cell type vulnerable to its own set of age-related phenotypes, the effects of ageing might in fact prove a prerequisite to ALS, rendering the cells susceptible to disease-specific mechanisms. Moreover, we discuss evidence for overlap between age and ALS-associated hallmarks, potentially implicating cell type-specific ageing as a key contributor to this multifactorial and complex disease. With a dearth of disease-modifying therapy currently available for ALS patients and a substantial failure in bench to bedside translation of other potential therapies, the unification of research in ageing and ALS requires high fidelity models to better recapitulate age-related human disease and will ultimately yield more reliable candidate therapeutics for patients, with the aim of enhancing healthspan and life expectancy.
Multi-Item Discriminability Pattern to Faces in Developmental Prosopagnosia Reveals Distinct Mechanisms of Face Processing
Authors: Tian Xue , Wang Ruosi , Zhao Yuanfang , Zhen Zonglei , Song Yiying , Liu Jia 
Published: October 2019

Abstract
Previous studies have shown that individuals with developmental prosopagnosia (DP) show specific deficits in face processing. However, the mechanism underlying the deficits remains largely unknown. One hypothesis suggests that DP shares the same mechanism as normal population, though their faces processing is disproportionally impaired. An alternative hypothesis emphasizes a qualitatively different mechanism of DP processing faces. To test these hypotheses, we instructed DP and normal individuals to perceive faces and objects. Instead of calculating accuracy averaging across stimulus items, we used the discrimination accuracy for each item to construct a multi-item discriminability pattern. We found DP’s discriminability pattern was less similar to that of normal individuals when perceiving faces than perceiving objects, suggesting that DP has qualitatively different mechanism in representing faces. A functional magnetic resonance imaging study was conducted to reveal the neural basis and found that multi-voxel activation patterns for faces in the right fusiform face area and occipital face area of DP were deviated away from the mean activation pattern of normal individuals. Further, the face representation was more heterogeneous in DP, suggesting that deficits of DP may come from multiple sources. In short, our study provides the first direct evidence that DP processes faces qualitatively different from normal population.
Temporal Differences in Interneuron Invasion of Neocortex and Piriform Cortex during Mouse Cortical Development
Authors: Hsing Hsiang-Wei , Zhuang Zi-Hui , Niou Zhen-Xian , Chou Shen-Ju 
Published: October 2019

AbstractEstablishing a balance between excitation and inhibition is critical for brain functions. However, how inhibitory interneurons (INs) generated in the ventral telencephalon integrate with the excitatory neurons generated in the dorsal telencephalon remains elusive. Previous studies showed that INs migrating tangentially to enter the neocortex (NCx), remain in the migratory stream for days before invading the cortical plate during late corticogenesis. Here we show that in developing mouse cortices, INs in the piriform cortex (PCx; the major olfactory cortex) distribute differently from those in the NCx. We provide evidence that during development INs invade and mature earlier in PCx than in NCx, likely owing to the lack of CXCR4 expression in INs from PCx compared to those in NCx. We analyzed IN distribution patterns in Lhx2 cKO mice, where projection neurons in the lateral NCx are re-fated to generate an ectopic PCx (ePCx). The PCx-specific IN distribution patterns found in ePCx suggest that properties of PCx projection neurons regulate IN distribution. Collectively, our results show that the timing of IN invasion in the developing PCx fundamentally differs from what is known in the NCx. Further, our results suggest that projection neurons instruct the PCx-specific pattern of IN distribution.
A case report: metastasis of melanoma to the heart in an era of immunotherapy
Authors: Poulsen Christian B , Weile Kathrine S , Schmidt Henrik , Poulsen Steen H 
Published: October 2019

Abstract

Background
Cardiac metastasis of melanoma rarely causes heart failure symptoms and the recognition of cardiac involvement is in most cases first established post-mortem. Surgical removal might be considered in selected cases in patients with an inflow or outflow tract obstruction even though the survival remains poor. Frequently, the metastasis cannot be removed and therapeutic options include conventional chemotherapy or immunotherapy, which is currently recommended as first-line treatment. Since the introduction of immunotherapy survival in metastatic disease has significantly increased but data on patients treated for melanoma with cardiac involvement are scarce.

Case summary
A 65-year-old man presented with dyspnoea and fatigue. Computed tomography scan revealed tumour processes in the heart, which was confirmed on echocardiography. Biopsies taken from fluorodeoxyglucose positron emission tomography positive lymph nodes in the axilla and groin showed melanoma. Analyses did not reveal BRAF mutation and the PD-L1 expression in tumour cells was below 1%. Treatment with ipilimumab and nivolumab was initiated and cardiopulmonary symptoms subsided during the following months with significant reduction in cardiac metastasis on echocardiography. Unfortunately, the patient developed immune checkpoint inhibitor-induced colitis and could no longer continue on the therapy. Due to development of extra-cardiac and cerebral metastasis, he was referred to palliative care.

Discussion
This case demonstrates that timely treatment with immunotherapy could be a safe and effective option for melanoma with cardiac involvement. During treatment, the patient developed severe colitis, a known side effect to immunotherapy. Though this often can be managed with steroids it complicates further treatment.