bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study
Authors: Alessandrini Aurora , Starace Michela , Bruni Francesca , Brandi Nicolò , Baraldi Carlotta , Misciali Cosimo , Fanti Pier Alessandro , Piraccini Bianca Maria 
Published: October 2019

Background: Alopecia areata is a nonscarring hair loss that usually causes round patches of baldness, but alopecia areata incognita (AAI) and diffuse alopecia areata (DAA) can cause a diffuse and acute pattern of hair loss.
Objective: To analyze the clinical, trichoscopic, histological, and therapeutic features of AAI and DAA.
Methods: The study was designed to include data of patients with histological diagnosis of AAI and DAA enrolled in our Hair Disease Outpatient Consultations.
Results: DAA had a greater involvement of the parietal and anterior-temporal regions, while AAI manifested itself mainly in the occipital-parietal regions. The most frequent pattern was empty yellow dots, yellow dots with vellus hairs, and small hair in regrowth, but the presence of pigtail hair was found almost exclusively in those with AAI. In cases of DDA, the finding of dystrophic hair and black dots was more frequent. The most frequent trichoscopic sign in both diseases was the presence of empty yellow dots, which, however, were described in a higher percentage in cases of DAA. The diseases have a benign course and are responsive to topical steroid therapy.
Conclusions: Trichoscopy is very important for the differential diagnosis between the 2 diseases and to select the best site for biopsy. In the presence of diffuse hair thinning, these entities must be considered.
Lentigo Maligna of the Face: The Importance of Clinical, Dermoscopic, and Histological Correlation
Authors: Fensterseifer Giovana Serrão , Lodi Ana Paula , Dantas Manuela , Boff Ana Letícia , Lovatto Louise 
Published: October 2019

Citation: Serrão Fensterseifer G, Lodi AP, Lima Dantas M, Boff AL, Lovatto L. Lentigo maligna of the face: the importance of clinical, dermoscopic, and histological correlation. Dermatol Pract Concept. 2019;9(4): 292-294. DOI: https://doi.org/10.5826/dpc.0904a08
Accepted: July 21, 2019; Published: October 31, 2019
Copyright: ©2019 Serrão Fensterseifer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: None.
Competing interests: The authors have no conflicts of interest to disclose.
Authorship: All authors have contributed significantly to this publication.
Corresponding author: Dr. Giovana Serrão Fensterseifer, Rua Professor Annes Dias, 135-Hospital Santa Clara, Santa Casa Porto Alegre, Brazil. Email: gfensterseifer@gmail.com
Titanium Nitride Modified Photoluminescence from Single Semiconductor Nanoplatelets
Authors: Peng Lintao , Wang Xuejing , Coropceanu Igor , Martinson Alex B. , Wang Haiyan , Talapin Dmitri V. , Ma Xuedan 
Published: October 2019

AbstractTitanium nitride (TiN) is an alternative plasmonic material that has the potential for visible and near‐infrared optical applications due to its distinct properties. Here, coupling effects between TiN nanohole array films and nearby excitonic emitters, semiconductor nanoplatelets (NPLs), are investigated using single particle spectroscopy. At the emission wavelength of the NPLs, the local field enhancement close to the surface of the TiN nanohole array films induces an increase in the radiative decay rates of the emitters by a factor of up to 2. This effect diminishes quickly as the distance between the TiN nanohole array films and emitters increases. At short wavelengths where the NPLs are excited, the TiN nanohole array films exhibit lossy dielectric characteristics. Local field modification at these wavelengths leads to a reduced local density of electromagnetic states, and hence the photoluminescence intensity of the emitters. This study shows the potential of TiN as an alternative plasmonic material for optoelectronic and photonic applications, especially in the long wavelength ranges.
Efficient Photocatalytic Nitrogen Fixation: Enhanced Polarization, Activation, and Cleavage by Asymmetrical Electron Donation to NN Bond
Authors: Yuan Jili , Yi Xuanying , Tang Yanhong , Liu Meijun , Liu Chengbin 
Published: October 2019

AbstractPhotocatalytic nitrogen (N2) fixation suffers from low efficiency due to the difficult activation of the strongly nonpolar NN bond. In this study, a Ru–Co bimetal center is constructed at the interface of Ru/CoSx with S‐vacancy on graphitic carbon nitride nanosheets (Ru‐Vs‐CoS/CN). Upon adsorption, the two N atoms in N2 are bridged to the Ru–Co center, and the asymmetrical electron donation from Ru and Co atoms to N2 adsorbate highly polarized NN bond to double bond order. The plasmonic electric‐field‐enhancement effect enables the Ru/CoSx interface to boost the generation of energetic electrons. The Schottky barrier between Ru and CoSx endows the interface with electron transfer from CoSx to Ru. The Ru‐end bound N at the Ru–Co center is preferentially hydrogenated. As a result, the Ru‐Vs‐CoS/CN photocatalyst shows an NH3 production rate of up to 0.438 mmol g−1 h−1, reaching a high apparent quantum efficiency of 1.28% at 400 nm and solar‐to‐ammonia efficiency of 0.042% in pure water under AM1.5G light irradiation.
Cu(II)‐Mediated C−C/C−O Bond Formation via C−H/C−C Bond Cleavage: Access to Benzofurans Using Amide as a Traceless Directing Group
Authors: Yu Shuling , Lv Ningning , Liu Zhanxiang , Zhang Yuhong 
Published: October 2019

AbstractA copper‐mediated synthesis of 2,3‐disubstituted benzofurans with the assistance of an 8‐aminoquinolyl auxiliary is described from readily available benzamides and benzoylacetonitriles. In this reaction, the C−C bond is successfully constructed via C−H activation, and C−O bond is subsequently formed at the original position of the amide group in a one‐pot manner. The amide directing group is detached simultaneously under the reaction conditions through C−C bond cleavage. Surprisngly, the distinct isoquinolinone products can be achieved by changing the reaction conditions using ammonia as amine source.magnified image
Photovoltaic Voltage Regulation through Distributed Power Compensation Considering Communication Delay
Authors: Zhang Zhanqiang , Dou Chunxia , Yue Dong , Zhang Bo , Zhang Tengfei 
Published: October 2019

AbstractTo solve the overvoltage problem in high penetration photovoltaic (PV) system, a new voltage regulation method is proposed. First, the node voltage sensitivity to PV power is calculated. Next, an optimal power compensation scheme using a new compensation mechanism is obtained so that the node voltage can be acceptably regulated with minimum power curtailment. The maximum tolerable communication delay is also estimated based on PV power mutation during communication delay (CD). Because extreme learning machine (ELM) algorithms exhibit fast and precise prediction, they can be used here to predict PV power. Based on the predicted power, the power compensation can be appropriately corrected to achieve effective voltage regulation under abnormal CD (ACD). Finally, the results indicate that voltage deviation can be regulated to an acceptable range of 1.00–1.05 per unit by using the proposed power compensation approach to curtail reactive power or even active power. The maximum PV power error predicted by ELM algorithm is only 2.67%, which is an acceptable basis for power compensation correction under ACD. Hence, by curtailing additional PV power again, the effective voltage regulation can be finally ensured under power mutation with ACD.
Plasma levels of adiponectin and chemerin are associated with early stage of atherosclerosis in older adults with type 2 diabetes mellitus
Authors: Li Huahua , Zhan Junkun , Liao Bin , Wang Yanjiao , Liu Youshuo 
Published: October 2019

AbstractObjectiveAdipokines, such as adiponectin and chemerin, regulate fat metabolism and are critical for the development of atherosclerosis. Investigating the correlations of adiponectin and chemerin with atherosclerosis in older adults with type 2 diabetes mellitus (T2DM) will shed light on the search for new markers for early diagnosis of diabetic atherosclerosis.MethodsA total of 120 older T2DM patients and nine healthy controls were enrolled in this study. The clinical parameters, such as brachial‐ankle pulse wave velocity (ba‐PWV), adiponectin, and chemerin, were examined and recorded. T2DM subjects were divided into three groups according to ba‐PWV level (high, medium, or low). The data were processed and analyzed by identical methods.ResultsSignificantly higher chemerin and lower adiponectin levels were detected in the plasma of T2DM patients than in healthy controls. The plasma levels of chemerin and adiponectin were negatively correlated in T2DM patients. Moreover, chemerin and adiponectin were significantly correlated with body mass index, ankle‐brachial index, insulin, and ba‐PWV. Multiple linear regression analysis revealed that chemerin and adiponectin were independently affecting ba‐PWV.ConclusionAdiponectin and chemerin are potential markers for diagnosis and monitoring of early stage of atherosclerosis in older adults with T2DM. Further clinical investigations are required to confirm these markers.
Bain type of X‐linked syndromic mental retardation in a male with a pathogenic variant in HNRNPH2
Authors: Somashekar Puneeth H. , Narayanan Dhanya L. , Jagadeesh Sujatha , Suresh Beena , Vaishnavi Reddy D. , Bielas Stephanie , Girisha Katta M. , Shukla Anju 
Published: October 2019

AbstractHeterogeneous nuclear ribonucleoproteins (hnRNPs) are RNA binding proteins, which aid in maturation, stabilization, and transport of mRNA. They have a significant role in cellular nucleic acid metabolism. The hnRNPs alter gene expression and are linked to various neurodegenerative disorders and cancers. Previously, six unrelated girls with developmental delay, intellectual disability, and hypotonia were found to have de novo heterozygous pathogenic missense variants in HNRNPH2, located on the X chromosome. A gain‐of‐function effect was proposed for the variant and it was thought to be lethal in males as no surviving males were identified. We describe a family with two affected siblings, one male and one female, with a known pathogenic variant in HNRNPH2, possibly due to maternal germline mosaicism.
QCM‐D assay for quantifying the swelling, biodegradation, and protein adsorption of intelligent nanogels
Authors: Clegg John R. , Ludolph Catherine M. , Peppas Nicholas A. 
Published: October 2019

ABSTRACTEnvironmentally responsive nanomaterials have been developed for drug delivery applications, in an effort to target and accumulate therapeutic agents at sites of disease. Within a biological system, these nanomaterials will experience diverse conditions which encompass a variety of solute identities and concentrations. In this study, we developed a new quartz crystal microbalance with dissipation (QCM‐D) assay, which enabled the quantitative analysis of nanogel swelling, protein adsorption, and biodegradation in a single experiment. As a proof of concept, we employed this assay to characterize non‐degradable and biodegradable poly(acrylamide‐co‐methacrylic acid) nanogels. We compared the QCM‐D results to those obtained by dynamic light scattering to highlight the advantages and limitations of each method. We detailed our protocol development and practical recommendations, and hope that this study will serve as a guide for others to design application‐specific QCM‐D assays within the nanomedicine domain. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48655.
Mass spectrometry imaging: An emerging technology for the analysis of metabolites in insects
Authors: Yang Fei‐Ying , Chen Jun‐Hui , Ruan Qian‐Qian , Saqib Hafiz S. A. , He Wei‐Yi , You Min‐Sheng 
Published: October 2019

AbstractMass spectrometry imaging (MSI) can visualize the composition, abundance, and spatial distribution of molecules in tissues or cells, which has been widely used in the research of life science. Insects, especially the agricultural pests, have received a great deal of interests from the scientists in biodiversity and food security. This review introduces the major characteristics of MSI, summarizes its application to the investigation of insect endogenous metabolites, exogenous metabolites, and the spatiotemporal changes of metabolites between insects and plants, and discusses its shortfalls and perspectives. The significance of these concerns is beneficial for future insect research such as physiology and metabolism.
Exponential and weak stabilization for distributed bilinear systems with time delay via bounded feedback control
Authors: Tsouli Azzeddine , El Houch Atmane 
Published: October 2019

AbstractIn this paper, we deal with the problem of exponential and weak stabilization for a class of distributed bilinear systems with time delay in a Hilbert space by using bounded feedback control. In the case of exponential stabilization, an explicit decay rate estimate of the stabilized state is given provided that a non‐standard observability inequality condition is satisfied. The compactness hypothesis of the control operator prevents the validity of the non‐standard observability inequality, thus it can be relaxed to a weaker sufficient condition to show the weak stabilization result by employing the same feedback control. Finally, numerical examples and simulations to hyperbolic and parabolic partial functional differential equations are considered to illustrate the effectiveness of the obtained theoretical results.
An oppositeness in the cosmology: Distribution of the gamma ray bursts and the cosmological principle
Authors: Mészáros Attila 
Published: October 2019

AbstractThe Cosmological Principle is the assumption that the universe is spatially homogeneous and isotropic on the large‐scale average. In 1998, the author, together with his two colleagues, demonstrated that the BATSE's short gamma ray bursts are not distributed isotropically in the sky. This claim was then followed by other papers confirming both the existence of anisotropies in the angular distribution of bursts and the existence of huge Gpc structures in the spatial distribution. These observational facts are in contradiction with the Cosmological Principle because the large‐scale average can hardly be provided. The aim of this study is to survey these publications.
The use of the Monte Carlo methods in studying Fanaroff‐Riley II‐type radio sources
Authors: Kuligowska Elżbieta Marzena 
Published: October 2019

AbstractGeneral Monte Carlo methods are a broad class of algorithms relying on repeated random sampling to obtain numerical results in many physical problems. The underlying concept is to use randomness to solve problems that might be deterministic in principle. They are often used in problems with many coupled degrees of freedom. I present the possible use of these methods in the case of the analytical KDA (Kaiser, Dennett‐Thorpe & Alexander, 1997) model of Fanaroff‐Riley's II (FR II)‐type radio sources assuming the continuum injection process in the jet–intergalactic medium interaction. Since this model is characterized by a large number of free parameters and originally requires knowing the large number of parameters unknown a priori, the use of the Monte Carlo methods is well justified. I discuss the application of these methods and its reliability in the case of the selected real radio sources.
The study of coherent optical pulsations of the millisecond pulsar PSR J1023+0038 on Russian 6‐m telescope
Authors: Karpov Sergey , Beskin Grigory , Plokhotnichenko Vladimir , Shibanov Yuri , Zyuzin Dmitry 
Published: October 2019

AbstractWe observed the millisecond redback pulsar PSR J1023+0038 in its accreting regime on two nights in November 2017 on Russian 6‐m telescope with a high‐temporal resolution panoramic photometer‐polarimeter in a two‐channel (“blue” and “red”) setup. During 400 s (12% of nearly 3 hr of total observations), we detected coherent optical pulsations in both color bands with 1.69‐ms period, corresponding to the rotational period of neutron star known from the radio data, with amplitudes of 2.1% (“red”) and 1.3% (“blue”). Corresponding luminosity of pulsed component is about 1031 erg s−1 and may be caused by a synchrotron emission of electrons with moderate Lorentz factors close to a light cylinder during the interaction of accretion disk with ejected matter modulated with rotational period.
Applying weighted image coaddition to observations of GRB optical afterglows at the D50 telescope in Ondřejov
Authors: Jelínek Martin , Kann David A. , Štrobl Jan , Hudec René 
Published: October 2019

AbstractOne of the primary observational objectives of the 0.5 m robotic telescope of Ondřejov observatory is the ground‐based follow‐up of gamma‐ray burst triggers. This independent robotic observatory has been in operation since 2008 and has followed up more than a hundred events localized by the Swift or INTEGRAL satellites. We describe the use of the weighted coaddition of astronomical images while applying this method to observations of GRB optical afterglows. We present optical photometric observations of the detected optical afterglows. The collection contains several faint optical afterglows, in some cases a lightcurve is available, in some cases only a single point detection has been achieved. A brief collection of available information is presented for each of the events together with our fitting and analysis.
The first observation of an optical counterpart to a short gamma‐ray burst from the Czech Republic: GRB 160927A
Authors: Trčka Šimon , Jelínek Martin , Štrobl Jan 
Published: October 2019

AbstractWe present the earliest observations of the short Gamma‐Ray Burst, GRB 160927A, by the D50 telescope from the Ondřejov Observatory. The 50‐cm robotic telescope reacted to the alert of GRB 160927A and started obtaining unfiltered images 40 s after the trigger with a total exposure of 7,230 s. The magnitude obtained by D50 reached 22.4 ± 0.3 mag not corrected for the galactic foreground extinction of 0.2 mag. We obtained the temporal decay index with α = 0.93 ± 0.03 and the spectral slope with β = 0.68 ± 0.2.
RISEPix—A Timepix‐based radiation monitor telescope onboard the RISESAT satellite
Authors: Filgas Robert , Malich Milan , Kuwahara Toshinori , Broulím Jan , Holík Michael , Sakal Morokot , Murata Yu , Tomio Hannah , Gohl Stefan , Pineda T. Johan M. 
Published: October 2019

AbstractRapid International Scientific Experiment Satellite (RISESAT) is a small Japanese experimental Earth‐observing, science and technology demonstration satellite. One of the scientific instruments onboard is a miniature radiation monitor telescope RISEPix with two Timepix detectors, developed and built at the Institute of Experimental and Applied Physics, Czech Technical University in Prague. After its successful launch in January 2019, RISESAT joined two other still operational satellites with our Timepix‐based radiation monitors, SATRAM onboard the ESA satellite Proba‐V (launched in 2013) and the Czech VZLUSAT‐1 cubesat (launched 2017). In this work, we present general technical and scientific details about the RISESAT satellite mission and the RISEPix module, and a basic comparison of space weather monitoring from SATRAM and VZLUSAT‐1 radiation monitors.
Robustheit gedrungener Stahlbetonstützen
Authors: Empelmann Martin , Matz Henrik 
Published: October 2019

AbstractEin robustes Tragwerk soll die Auswirkungen von unplanmäßigen Einwirkungen so begrenzen, dass diese in einem vertretbaren Verhältnis zur Ursache stehen. Ein schlagartiges Versagen oder ein progressiver Kollaps muss verhindert werden. Im Rahmen einer Gesamtanalyse ist die Kenntnis über das Verhalten der maßgebenden Einzelbauteile unverzichtbar. Während ein schlagartiges Zugversagen bei biegebeanspruchten Bauteilen durch die Mindestbiegezugbewehrung verhindert wird, kann ein robustes Bauteilversagen bei Stahlbetonstützen durch die derzeitigen Regelungen zur konstruktiven Durchbildung nicht in allen Fällen garantiert werden. Zur Beleuchtung dieses Defizits gibt der vorliegende Beitrag zunächst einen Überblick über die Robustheit von Stahlbetonstützen. Es wird ein Modell vorgestellt, mit dem das Trag‐ und Nachbruchverhalten von Stahlbetonstützen praxisnah abgebildet werden kann und mit dem eine einfache Einschätzung der Robustheit möglich ist. Anschließend werden an einem Beispiel Maßnahmen zur gezielten Beeinflussung der Robustheit von Stahlbetonstützen untersucht.
The influence of green marketing strategies on business performance and corporate image in the retail sector
Authors: Mukonza Chipo , Swarts Ilze 
Published: October 2019

AbstractGreen marketing strategies are employed by many enterprises to enhance their corporate image and business performance. Green marketing is perceived as the commitment of a business or an organisation towards the development of safe, eco‐friendly goods and services by employing recyclable and easily decomposed packaging, better pollution prevention methods, and a more efficient use of energy. Against this background, the study followed a case study approach using South Africa's retail giants, Woolworths and Pick n Pay. Stratified purposive sampling was used to carry out in‐depth interviews and administer questionnaires with senior management of the selected retailers. In addition, document and website analyses were used for triangulation purposes. Path analysis and content analysis were used to establish the correlation. The study established that green marketing strategy has a positive effect on corporate image and on business performance. The paper recommends that if enterprises are to sustain competitive advantage, particularly in the retail sector, it is in their best interest to adopt green marketing strategies.
FEN1 inhibitor increases sensitivity of radiotherapy in cervical cancer cells
Authors: Li Jin‐Li , Wang Jian‐Ping , Chang Hong , Deng Sheng‐Ming , Du Jia‐Hui , Wang Xiao‐Xiao , Hu He‐Juan , Li Dong‐Yin , Xu Xiang‐Bin , Guo Wei‐Qiang , Song Yao‐Hua , Guo Zhigang , Sun Min‐Xuan , Wu Yi‐Wei , Liu Song‐Bai 
Published: October 2019

AbstractBackgroundCervical cancer is one of the most common causes of cancer‐associated mortality among affected women in the world. At present, treatment with weekly cisplatin plus ionizing radiation (IR) therapy is the standard regimen for cervical cancer, especially for locally advanced cervical cancer. The purpose of this study is to determine whether FEN1 inhibitors could enhance the therapeutic effect of IR therapy.MethodsWestern blot was applied to determine the expression of FEN1‐ and apoptosis‐related proteins. Cell growth inhibition assay and colony formation assay were used to determine the effects of FEN1 inhibitor and IR exposure for Hela cells in vitro. CRISPR technology was used to knockdown FEN1 expression level of 293T cells, and tumor xenograft in nude mice was employed to determine the effects of FEN1 inhibitor and IR exposure on tumor growth in vivo.ResultsOur data revealed that FEN1 is overexpressed in HeLa cell and can be upregulated further by IR. We also demonstrated that FEN1 inhibitor enhances IR sensitivity of cervical cancer in vitro and in vivo.ConclusionFEN1 inhibitor SC13 could sensitize radiotherapy of cervical cancer cell.