bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simulated operation combines patient-specific guide technology is superior to conventional technology for supramalleolar osteotomy: a retrospective comparative study
Authors: Wang Chenggong , Xu Can , Li Yusheng , Li Mingqing , Zhong Da , Wang Long , Liu Hua 
Published: March 2020

Abstract
Background: Over the past seven years, our team has designed a simulated operation combines patient-specific guide (SO-PSI) assisted supramalleolar osteotomy (SMOT) method and applied it to the clinic. This study aimed to determine the difference between SO-PSI technology and conventional operation (CO) technology for SMOT in preoperative planning, intraoperative application and postoperative curative effect. Methods: We retrospectively analyzed the data of SMOT in our hospital between October 2014 and December 2018; 28 patients were enrolled and divided into CO group (n=17) and SO-PSI group (n=11); the mean follow-up time was 33.4 (range, 13 to 59) months. We analyzed and compared perioperative data, accuracy of preoperative planning and intraoperative application, difference between pre- and post-operative of radiologic ankle angles, and change of AOFAS score, VAS, range of motion of ankle and Takakura stage after operation. Then we performed statistical analyses. Results: All ankle alignments and positions of two groups have been recovered. Compared with CO group, SO-PSI group has a shorter operative time and a postoperative hospital stay, a decreased number of fluoroscopies and a reduction of albumin, a longer preoperative planning time and a preoperative hospital stay and an increased hospitalization expenses. In SO-PSI group, the ankle angles between preoperative planning and postoperative shown good correlation, but not in CO group; the mean tibial ankle center discrepancy of SO-PSI group was 1.86±1.06 mm. After follow-up, all radiologic parameters of two groups significantly improved, but the improvement of tibial anterior surface angle and tibiotalar tilt angle of SO-PSI group were more obvious than that of CO group; AOFAS score, VAS, range of motion of ankle and Takakura stage of two groups improved after operation; but overall the improvements of SO-PSI group were better than the CO group. Conclusions: SO-PSI technology can carry out the preoperative plan accurately and quickly in SMOT; In general, compared with the conventional technology, SO-PSI technology has advantages in preoperative planning, intraoperative application and postoperative curative effect. Keywords: Supramalleolar osteotomy; Simulated operation; Patient-specific guide; Accuracy of preoperative planning; Practicability of application
Quantitative evaluation of range and metabolic activity of hepatic alveolar echinococcosis lesion microenvironment using PET/CT and multi-site sampling method
Authors: Aini Abudusalamu , Yimingjiang Maiweilidan , Yasen Aimaiti , Ran Bo , Jiang Tiemin , Li Xiaohong , Wang Jian , Aihaiti Kasimu , Ainiwa Aisika , Abulizi Aubuduaini , Shao Yingmei , Aji Tuerganaili , Wen Hao 
Published: March 2020

Abstract
Background: Alveolar echinococcosis (AE) lesion microenvironment (LME) is crucial site where parasite-host interactions happen and of great significance during surgery and obtaining liver samples for basic research targeting immunology. However, little is known about quantification of LME range and its’ metabolic activity regarding different lesion types. Materials and Methods: A prospective analysis of LME from consecutive surgical AE cases with relevant imaging results was performed. Patients (n=39) received abdominal computed tomography (CT) and position emission tomography/computed tomography using 18F-fluodeoxyglucose (18F-FDG-PET/CT) within one week prior to surgery. Tumor to background ratios (TBRs) of standard uptake value (SUV) in PET/CT was calculated for corresponding LME regions. Multi-site sampling method (MSS, n=26) was introduced to obtain histological slides from LME at different levels off the lesion to evaluate immune cell infiltrative ranges quantitatively. At last, data was statistically analyzed from the perspective of different lesion types. Results: Altogether six major lesion categories have been identified based on different morphology and calcification pattern (A: non-calcified uniform density lesion; B: diffuse calcified solid lesion; C: half necrotic and half solid lesion with minor calcification; D: half necrotic and half solid lesion with obvious calcification; E: subtotal necrotic lesion with minor calcification; F: total necrotic lesion with obvious calcification). Statistical significances were resulted from TBRs calculation (A>B, A>D, A>F, BB+D+F, etc.). Less calcified lesions were evidenced with higher TBRs, however, not much was valuable for necrosis. The 95% CI of LME ranges were (10.0, 12.1) mm and (9.9, 14.0) mm by PET/CT and MSS. And, weak regressions between TBRs and LME ranges indicated by PET/CT or MSS (r2 respectively were 0.2436 and 0.3171) were observed. Conclusions: PET/CT showed distinct TBRs for different lesion types with heterogenic calcification. PET/CT and MSS had similar discoverability for LME ranges, which also varied among different lesion types. Higher activity meant wider LME range within certain limit. This pioneering study would be able to provide references for both surgical removal of lesions and sample acquisitions more accurately for basic research targeted to immunology.
Prevention of Surgical Site Infection by Gentamicin-Impregnated Collagen Sponge (Collashield® Double Action) in Patients Who Underwent Abdominal Surgery
Authors: Lee Jin Won , Chun Wan Joo , Kim Hae Sung 
Published: March 2020

Abstract
Background: The aim of this study was to evaluate the efficacy of the gentamicin-impregnated collagen sponge (GCS) in preventing SSI after abdominal surgeries. Methods: We conducted a retrospective study to evaluate the effect of GCS in preventing postoperative surgical site infection (SSI) in patients who underwent abdominal surgeries. 194 patients (111 male and 83 female; mean age, 62 years; range, 20-96 years) who underwent abdominal surgery between January 2017 and December 2018 in Chuncheon Sacred Heart Hospital were included in this study. The primary endpoint was the development of any SSI within 1 month postoperatively. Results: Of 194 patients studied, 30(20.1%, control group) and 6(13.3%, sponge group) in each group developed a SSI. However, subgroup analysis in patients with contaminated and dirty wound showed that SSI was occurred more frequently in the control group (15 of 36 [41.7%]) than in the sponge group (3 of 22 [13.6%]) (P = 0.04). Our data suggest that postoperative SSI can be reduced by using GCS in in the group of patients with contaminated and dirty wound classes. Conclusions: The SSI rate after abdominal surgeries was reduced in the group of patients with contaminated and dirty wound classes, by using GCS. We should consider to use GCS in patients with these type of wounds. Key words: Surgical Site Infection(SSI), Abdominal Surgery, Gentamicin-Impregnated
The Correlation of Hip Joint Passive Range of Motion with Lower Limbs Injuries in Professional Soccer Players
Authors: Karaminia Elham , Angoorani Hoomam , Mazaherinezhad Ali , Hassanmirzaei Bahar , Moghadam Navid 
Published: March 2020

Abstract
Introduction : Soccer is a popular sport with a high injury rate. Lower limb injuries are accounted for 85% of injuries in professional Soccer player. It is important to identify the predisposing factors in professional Soccer players for screening players at an increased risk of injury. It is unclear whether to assume limited hip range of motion (ROM) as one of these factors this study aimed to evaluate the association between hip passive ROM and lower limb injury in Iranian professional Soccer players.Design : This prospective cohort study was conducted on 266 male professional Soccer players (with a mean age of 24.91 ± 4.38 years) playing in the Iran Soccer Premium League during the 2017-2018 and 2018-2019 season. Baseline hip joint passive ROM was evaluated in all subjects. All athletes were followed for two consecutive seasons and their lower limb injuries causing at least an absent from a competitive match was reported. The association between hip ROM and the incidence of lower limb injuries was analyzed.Results : The most common lower limb injuries were ankle and foot injuries (12.4%), groin pain (11.5%) and muscle strain (10.9%), respectively. Restricted hip internal rotation (IR) was associated with a higher incidence of groin pain, ACL injury and knee injury. A significant correlation was observed between decreased hip external rotation (ER) with muscle strain and knee injuries. The higher knee injury was also associated with reduced hip abduction. There was no association between ankle and foot injuries and hip passive ROM.Conclusions : This study showed that hip passive ROM could be used to identify Soccer players at a higher risk of lower limb injuries. Hip rotational ROM and abduction limitation were significantly associated with the incidence of several common Soccer injuries, including groin pain, muscle strain and ACL/knee injuries and precedes their development and could be used as a screening tool for professional male soccer players.
Angiotensin II receptor 1 antibodies associate with post transplant focal segmental glomerulosclerosis and proteinuria
Authors: Abuzeineh Mohammad , Aala Amtul , Alasfar Sami , Alachkar Nada 
Published: March 2020

Abstract
Background

Angiotensin II type 1 receptors (AT1Rs) are expressed on podocytes, and play an essential role in the maintenance of vascular homeostasis. The presence of AT1R antibodies (AT1R-Abs) leads to activation of these receptors resulting in endothelial cell dysfunction and podocyte injury. We assessed the correlation between AT1R-Abs and the risk of post transplant FSGS.

Methods

This is a retrospective study included all kidney transplant recipients with positive AT1R-Abs (≥9 units/ml), who were transplanted and followed at our institution between 2006-2016. We assessed the development of biopsy proven FSGS and proteinuria by urine protein to creatinine ratio of ≥ 1 g/g.

Results

We identified 100 patients with positive AT1R-Ab at the time of kidney transplant biopsy or proteinuria. 49 (49%) recipients (FSGS group) had biopsy-proven FSGS and/or proteinuria. Pre-transplant hypertension was present in 89% of the FSGS group compared to 72% in the non-FSGS group, p =0.027. 43% of the FSGS group were on angiotensin converting enzyme inhibitors or angiotensin receptor blockers prior to transplant, compared to 25.5% in the non-FSGS group, p =0.06 . Primary idiopathic FSGS was the cause of ESRD in 20% of the FSGS group, compared to 6% in the comparison group; p =0.03. The allograft loss was significantly higher in the FSGS group 63% compared to 39% in non-FSGS. Odds ratio and 95% confidence interval were 2.66 (1.18 -5.99); p =0.017.

Conclusions

Our data suggests a potential association between AT1R-Abs and post transplant FSGS leading to worse allograft outcome. Therefore, AT1R-Abs may be considered a biomarker for FSGS post transplant.
Deep Factor Analysis for Weather Varied Sense-through-foliage Target Detection
Authors: Xue Wenling , Jiang Ting , Sun Xuebin , Zheng Xiaokun , Ding Xue 
Published: March 2020

Abstract
In this paper, the influence of seasonal variation on target detection accuracy and the effectiveness of deep factor analysis(DFA) in signal denoising are studied. To extensively verify the universality of the proposed DFA approach, a variety of target objects, including no target, human, wood board and iron cabinet targets, are measured in foliage environment under four different weather conditions. Then, after removing background noise from the collected data, deep factor analysis is carried out to further reduce the impact of noise. The experimental results show that the influence of weather variation on target detection can be effectively eliminated by the presented DFA, which can improve the average classification accuracy in all seasons. At the end of the paper, it is verified by cross validation that the DFA method can be stabilized at around 93% even in hazy day and snowy day which has stability and universality in any weather conditions, even in snowy and haze days.
Research on Personnel Performance Evaluation Model Based on Neural Wireless Network Data Mining Algorithm
Authors: Liang Wei , Li Tingyi 
Published: March 2020

Abstract
In order to effectively evaluate personnel performance, a distributed data mining algorithm for spatial networks based on BP neural wireless network is proposed. In the cloud computing environment, an excavator is used to construct multiple input multiple output spatial network data, analyze the data structure, and perform redundant data compression of massive data through time-frequency feature extraction. Combined with adaptive matching filtering method, the characteristics of the data are matched. The spatial frequency feature extraction method is used to locate the features of the multiple-input multiple-output spatial network data, and the fourth-order cumulant slice is used for reorganization. Data in time series. In order to improve the accuracy of data mining, the BP neural network is used to classify and identify the extracted data features to achieve the optimization of data mining. This algorithm improves the accuracy of personnel performance evaluation, and simultaneously establishes a hierarchical analysis and quantitative evaluation model for the performance of government managers, and adjusts the results of hierarchical statistical analysis on government administrators as needed. The performance evaluation and optimization of government administrators were introduced. The empirical analysis results show that the method has higher accuracy for government managers' performance evaluation, higher efficiency of big data processing and better integration.
Different distribution of maternal red cell antibodies and risk on the severe alloimmune haemolytic disease of the foetus in a Chinese Population: a retrospective cohort study on prenatal management
Authors: Li Si , He Zhiming , Luo Yanmin , Ji Yanli , Luo Guangping , Fang Qun , Gao Yu 
Published: March 2020

Abstract
BACKGROUND: The distribution of antibodies that cause haemolytic disease of the foetus (HDF) in China and the effects of multiple antibodies on the severity of HDF are needed to further evaluation. METHODS: A retrospective cohort study was conducted in two affiliated Hospitals of Sun Yat-sen University. Total 268 pregnant women and foetuses pairs were divided into four groups: anti-D, anti-D combined others, other single-antibody and other multiple-antibody. The obstetrics history, the incidence of severe HDF and foetal outcomes were collected and compared in each group. The logistics regression analysis and the survival analysis were conducted for analysis. RESULTS: Anti-D was the most common cause of HDF, followed by the anti-M of MNS system. No anti-K or isolate anti-c associated HDF was found. Upon the mothers with anti-D combined other antibodies, the incidence of severe HDF was increased than those with anti-D alone(P=0.046). Foetuses in the other single-antibody group had lower reticulocytes (P=0.007), more IUT times (P =0.007) and an earlier onset of severe HDF (P=0.003). High maternal antibody titer (P＜0.001), multiple affected pregnancies (P＜0.001) and other single-antibody (P=0.030) were the independent risk factor for HDF developing. And the lower foetal haematocrit (P =0.012) and higher reticulocyte counts (P =0.035) were the independent risk factors of severe HDF in the anaemia foetuses affected by RhD alloimmunization. CONCLUSION: The distribution of HDF-associated antibodies in China is different from that in western countries. Other single non-Rh(D) and multiple antibodies could both increase the risk of HDF but anti-D combined with other antibody would not influence the severity of the disease than anti-D alone.
Investigating the Effects of picture book on Reducing Anxiety Caused by Intravenous Catheterization among School-aged Children(Randomized Clinical Trial)
Authors: Kanikzadeh Masoumeh , Tahmasebi Rahim , bahreini farideh , jahanpour faezeh 
Published: March 2020

Abstract
Background: Injections are the main factors provoking pain, fear, and anxiety among hospitalized children. The purpose of this study is investigating the Effects of picture book on Reducing Anxiety Caused by Intravenous Catheterization among School-aged Children. Methods: In this randomized control trial study, seventy 6-12 year-old children were randomly assigned to either intervention or control group. Data was collected from 70 patients at Pediatric Emergency Room in the central Hospital in Bushehr- Iran during the summer and autumn, 2017. The subjects’ anxiety was evaluated before, during, and after the procedure by using Observation Scale of Behavior Distress instrument. Chi-square, Mann-Whitney and Wilcoxon tests were used for data analysis. Results: The mean anxiety scores of the intervention group was significantly less than those of control group after intervention. In addition, a significant difference was observed before and after the intervention in terms of anxiety levels. Conclusions: The school-aged children’s orientation on the intravenous catheterization and serum infusion play a significant role in controlling and reducing their anxiety during and after the intervention. Based on the result we suggested using the picture book to reduce the children anxiety before Intravenous Catheterization. Keywords: anxiety, pediatric, Intravenous Catheterization, education, picture book Trial registration: Current Controlled Trials: IRCT2017041712830N22). 2017-05-29
Evaluation of the TRIP13 level in breast cancer and insights into potential molecular pathways
Authors: Lan Jin , Huang Jingzhan , Gao Yuan , Sun Jingbo , Zhang Longshan , Deng Yunyao , Liu Lixin , Liu Xiaolong 
Published: March 2020

Abstract
Background: TRIP13 is a member belonging to a large AAA+ ATPases protein super family. Emerging evidences had shown that TRIP13 may serve as an oncogene However, the function of TRIP13 in BC has not yet been elucidated. Methods: By utilizing the multiple database across BC, we presented the expression of TRIP13 in BC tissue and normal control. We then verified the expression of TRIP13 in patients with BC by immunohistochemical (IHC) staining. Kaplan-Meier plots were used to perform the survival analysis. Further, gene ontology (GO) analysis, gene set enrichment analysis (GSEA), and PPI (protein-protein interaction) network were performed to explore the biological function and potential regular pathway of TRIP13 in BC. Results: The multiple database and immunohistochemical (IHC) showed that higher TRIP13 expression in BC tissue compared to normal tissue. TRIP13 was highly exprssed in lung metastasis lesion compared with primary tumor in our BALB/C mice 4T1 BC models. Kaplan-Meier plots also revealed that high TRIP13 expression correlated to poor survival in patients with BC. Moreover, GSEA analysis revealed that TRIP13 was primarily enriched in the processes of cell division and proliferation. Finally 10 hub genes with a high score of connectivity were filtered from the PPI network, including MAD2L1, CDC20, CDC5L, CDK1, CCNA2, BUB1B, RAD51, SPO11, KIF11 and AURKB. Conclusion: High TRIP13 expression predicted poor prognosis and contributed tumor growth and metastasis in the BC. Thus, ARL3 may be a prognostic marker and therapeutic target for glioma. TRIP13 may be a favorable biomarker and effective therapeutic target for BC. Keywords: TRIP13; breast cancer; metastasis; bioinformatic analysis, prognosis
Country and Gender Differences in the Association between Violence and Cigarette Smoking Among Youth
Authors: Abu-Rmeileh Niveen ME , Alderete Ethel , Husseini Abdullatif , Livaudais-Toman Jennifer , Perez-Stable Eliseo J 
Published: March 2020

Abstract
Background: Exposure to violence in youth may be associated with subsequent substance use and other adverse health effects. This study examined tow middle-income areas with different levels and types of exposure to violence. Methods: Association of exposure to verbal and physical violence with cigarette smoking in the West Bank oPt (2008) and in Jujuy Argentina (2006) was examined using cross-sectional surveys of 14 to 17-year old youth in 7th to 10th grade using probabilistic sampling. Results: Violence exposure rates were more than double for Palestinian girls (99.6% vs. 41.2%) and boys (98.7% vs. 41.1%) compared with Argentineans. Argentinean girls had current smoking rates eight times higher than Palestinian girls (56.2% vs. 7.1%). Exposure to verbal (OR 2.3; 95% CI=1.2-4.6) and physical (OR 2.0; 95% CI=1.1.-3.7) violence from family members increased the odds of smoking among Palestinian girls. Verbal violence from family (Adjusted OR1.6; 95% CI=1.2-2.1) and physical violence from nonfamily members (Adjusted OR 1.8; 95% CI=1.2-2.8) increased the odds of smoking among Argentinean boys. Conclusion: Findings highlight the importance of producing context and gender specific evidence, to inform and increase the impact of targeted prevention strategies.
The C-reactive Protein to Albumin Ratio Predicts Postoperative Complication in Patients who Undergo Gastrectomy for Gastric Cancer
Authors: Lee Jin Won , Chun Wan Joo , Kim Hae Sung 
Published: March 2020

Abstract
Background The aim of this study was to evaluate the preoperative C-reactive protein (CRP) to albumin ratio (CAR) of patients with gastric cancer and to investigate the factors correlated with perioperative complications. Methods From March 2016 to December 2019, 128 patients who underwent curative gastrectomy for gastric cancer were enrolled in a retrospective study. The preoperative cutoff value of the CAR for predicting postoperative complications was 0.265 on receiver operating characteristic (ROC) curve analysis. Clinical characteristics were compared between patients with complications (Clavien-Dindo grade ≥2, n = 20) and without complications (Clavien-Dindo grade <2, n = 108). Results On univariate and multivariate analyses, estimated blood loss (EBL) during the operation (HR 1.003, p = 0.039) and CAR (HR 2.832, p = 0.045) were independent predictors of postoperative complications. Conclusions A high CAR was significantly associated with postoperative complications in patients with gastric cancer.