bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ciencia abierta
Authors: Abadal Ernest , Anglada Lluís 
Published: March 2020

La ciencia abierta es un cambio de modelo en la manera de hacer ciencia que supone realizar con una visión “abierta” (open) todas las etapas o fases de la investigación científica (diseño, recolección de datos, revisión, publicación, etc.). El objetivo de nuestro texto es analizar la evolución del concepto y de la denominación de ciencia abierta desde sus inicios previos hasta el empuje que le ha dado la Unión Europea (e-ciencia, ciencia interconectada, ciencia 2.0, ciencia abierta). También se quiere determinar cuáles son los elementos fundamentales que componen la ciencia abierta. Para ello, se han seleccionado y analizado los principales textos teóricos que han tratado sobre la cuestión, que han sido localizados a partir de consultas bibliográficas en las bases de datos Scopus y GoogleScholar. Como resultados, se pone de manifiesto que las denominaciones han sufrido más variaciones que propiamente el concepto y, en lo que respecta a los componentes, la ciencia abierta partió de cuatro elementos básicos (acceso abierto, datos abiertos, software libre, reproducibilidad) que se han ido ampliando hasta los ocho que constituyen el modelo propuesto por las recomendaciones de OSPP, que se están adoptando de manera amplia.
Open science represents a paradigm shift in the way science is conducted that involves performing all stages of scientific research (design, data collection, review, publication, etc.) with an “open” vision. Our aim is to analyze the evolution of the denomination and the concept of open science from its beginnings (e-science, interconnected science, science 2.0, open science). We also want to determine which are the fundamental elements that make up open science. This is a theoretical research based on the selection and analysis of the most important conceptual documents about open science, which have been found in the Scopus and GoogleScholar databases. As a result, it is shown that the denominations have undergone more variations than the concept itself. Regarding the components, open science started with four basic elements (open access, open data, open software, reproducibility) that have been extended to the eight that are considered in the model proposed by OSPP recommendations.
Aproximación al grado de conocimiento y aplicación de Big Data en las bibliotecas universitarias españolas
Authors: Ríos Hilario Ana Belén , Fraile Sastre Alberto 
Published: March 2020

Se analiza el grado de conocimiento e implantación de la tecnología Big Data y sus características principales en las bibliotecas universitarias españolas inscritas en REBIUN con el objetivo de observar si estas instituciones se encuentran capacitadas para la utilización y aprovechamiento de las ventajas del tratamiento masivo de datos. Los datos son obtenidos mediante un cuestionario cuya respuesta proviene de fuentes internas de las bibliotecas, a partir de los cuales se establecen una serie de conclusiones junto a unas propuestas de mejora y líneas de trabajo futuras que permitan la correcta implantación, uso y aprovechamiento del Big Data en la oferta de servicios y funciones de las bibliotecas universitarias españolas.
It is analyzed the degree of knowledge and implementation of Big Data technology and its main characteristics in the Spanish university libraries registered in REBIUN, with the objective of observing if these institutions are qualified for the use of the advantages of the massive data processing. The data is obtained by means of a questionnaire, whose response comes from internal sources of the libraries, from which a series of conclusions are established together with proposals for improvement and future lines of work that allow the correct implementation, use and exploitation of the Big Data in the offer of services and functions of the Spanish university libraries.
Identification of a three-m6A related gene risk score model as a potential prognostic biomarker in clear cell renal cell carcinoma
Authors: Zhao Yiqiao , Tao Zijia , Chen Xiaonan 
Published: March 2020

Background
Clear cell renal cell carcinoma (ccRCC) is one of the most prevalent malignancies worldwide, N6-methyladenosine (m6A) has been shown to play important roles in regulating gene expression and phenotypes in both health and disease. Here, our purpose is to construct a m6A-regulrator-based risk score (RS) for prediction of the prognosis of ccRCC.

Methods
We used clinical and expression data of m6A related genes from The Cancer Genome Atlas (TCGA) dataset and the Least Absolute Shrinkage and Selection Operator (LASSO) Cox regression analysis to develop an RS to predict survival of patients with ccRCC, and analyzed correlations between RS and other clinical indicators such as age, grade and stage. Validation of this RS was then engaged in another cohort, E-MTAB-1980 from the ArrayExpress dataset. Finally, we used quantitative real-time PCR to analyze the expression profile of genes consists of the RS.

Results
A three-gene RS including METTL3, METTL14 and HNRNPA2B1 which can predict overall survival (OS) of ccRCC patients from TCGA. After applying this RS into the validation cohort from Arrayexpress, we found that it successfully reproduced the result; furthermore, the results of PCR validation were in line with our analysis.

Conclusion
To sum up, our study has identified an RS composed of m6A related genes that may predict the prognosis of ccRCC patients, which might be helpful for future therapeutic strategies. Our results call for further experimental studies for validations.
Batch Adsorption of Safranin Dye from an Aqueous Solution of Balanites aegyptiaca Seed Coats
Authors: Magaji Buhari , Maigari Aisha U. , Abubakar Usman A. , Sani Mukhtar M. , Maigari Amina U. 
Published: March 2020

This study was aimed at using Balanite aegyptiaca seed coats activated carbon (BAAC) as a potential adsorbent to remove safranin dye from aqueous solution. BAAC was prepared from Balanite aegyptiaca seed coats using a one-step procedure with 67.27% yield, 3.23% ash content, 695 m2/g surface area and 203 mg/g iodine number. The FTIR spectroscopy revealed O-H, N-H, C-H, C=C, C-O-H stretching vibrations. The influences of agitation time, initial dye concentration and adsorbent dose were studied in batch experiments at room temperature. The adsorptions were rapid at the first 15 minutes of agitation, with the uptake of 2.746 mg/kg. The adsorption equilibrium was achieved at 90 minutes of agitation. Kinetic studies showed good correlation coefficient for both pseudo-first order and pseudo-second-order kinetics model but fitted well into pseudo-second order kinetic model. The adsorption data fitted well into Langmuir isotherm with correlation coefficient (R2) very close to unity and Langmuir maximum adsorption constant, qm 1.00. Thus, the fitting into Langmuir indicates monolayer coverage on the adsorbents. The results showed that BAAC has the potential to be applied as alternative low-cost adsorbents in the remediation of dye contamination in wastewater.
Surface‐Enhanced Raman Spectroscopy: General Introduction
Authors: Ding Song‐Yuan , Zhang Xue‐Min , You En‐Ming , Ren Bin , Tian Zhong‐Qun 
Published: March 2020

AbstractThe surface‐enhanced Raman scattering effect refers to the effect was discovered in the mid‐1970s, by which the intrinsically low detection sensitivity of Raman spectroscopy is no longer a fatal disadvantage for this analytical tool. As a general introduction of surface‐enhanced Raman spectroscopy (SERS), the over 40‐year history of SERS is first overviewed, showing that SERS has gone through a tortuous pathway to develop into a powerful diagnostic technique. We then describe the principle of SERS and enhancement mechanisms, illustrating that SERS is mainly surface plasmon resonance (SPR) and nanostructure‐enhancement phenomenon. The SERS measurement procedures, in particular the preparation of various SERS active substrates, are discussed. Based on the four important criteria in analytical science, i.e. detection sensitivity (energetic, spatial, and temporal), resolution, generality, and reliability, we highlight two different approaches to utilize the strength and offset the weakness of SERS. With the enormously high sensitivity and spectral resolution, SERS has been applied successfully to surface analysis and trace analysis by gaining meaningful information from an extremely small quantity of species even down to single molecules. To significantly improve the surface generality and spatial resolution, tip‐enhanced Raman spectroscopy (TERS) was invented in 2000. To greatly improve the material generality and measurement reliability, shell‐isolated nanoparticle‐enhanced Raman spectroscopy (SHINERS) was introduced in 2010. Finally, prospective developments of SERS in substrates, methods, and theory are briefly discussed.
Optically Transparent Multiscale Composite Films for Flexible and Wearable Electronics
Authors: Lim Young‐Woo , Jin Jungho , Bae Byeong‐Soo 
Published: March 2020

AbstractOne of the key breakthroughs enabling flexible electronics with novel form factors is the deployment of flexible polymer films in place of brittle glass, which is one of the major structural materials for conventional electronic devices. Flexible electronics requires polymer films with the core properties of glass (i.e., dimensional stability and transparency) while retaining the pliability of the polymer, which, however, is fundamentally intractable due to the mutually exclusive nature of these characteristics. An overview of a transparent fiber‐reinforced polymer, which is suggested as a potentially viable structural material for emerging flexible/wearable electronics, is provided. This includes material concept and fabrication and a brief review of recent research progress on its applications over the past decade.
2D MXene–TiO2 Core–Shell Nanosheets as a Data‐Storage Medium in Memory Devices
Authors: Lyu Benzheng , Choi Yongsuk , Jing Hongyue , Qian Chuan , Kang Hyunseok , Lee Sungjoo , Cho Jeong Ho 
Published: March 2020

AbstractMXenes, an emerging class of 2D transition metal carbides and nitrides with the general formula Mn+1XnTx (n = 1–4), have potential for application as floating gates in memory devices because of their intrinsic properties of a 2D structure, high density‐of‐states, and high work function. In this study, a series of MXene–TiO2 core–shell nanosheets are synthesized by deterministic control of the surface oxidation of MXene. The floating gate (multilayer MXene) and tunneling layer (TiO2) in a nano‐floating‐gate transistor memory (NFGTM) device are prepared simultaneously by a facile, low‐cost, and water‐based process. The memory performance is optimized via adjustment of the thickness of the oxidation layer formed on the MXene surface. The fabricated MXene NFGTMs exhibit excellent nonvolatile memory characteristics, including a large memory window (>35.2 V), high programming/erasing current ratio (≈106), low off‐current (<1 pA), long retention (>104 s), and cyclic endurance (300 cycles). Furthermore, synaptic functions, including the excitatory postsynaptic current/inhibitory postsynaptic current, paired‐pulse facilitation, and synaptic plasticity (long‐term potentiation/depression), are successfully emulated using the MXene NFGTMs. The successful control of MXene oxidation and its application to NFGTMs are expected to inspire the application of MXene as a data‐storage medium in future memory devices.
Optimization of the Pore Structures of MOFs for Record High Hydrogen Volumetric Working Capacity
Authors: Zhang Xin , Lin Rui‐Biao , Wang Jing , Wang Bin , Liang Bin , Yildirim Taner , Zhang Jian , Zhou Wei , Chen Banglin 
Published: March 2020

AbstractMetal–organic frameworks (MOFs) are promising materials for onboard hydrogen storage thanks to the tunable pore size, pore volume, and pore geometry. In consideration of pore structures, the correlation between the pore volume and hydrogen storage capacity is examined and two empirical equations are rationalized to predict the hydrogen storage capacity of MOFs with different pore geometries. The total hydrogen adsorption under 100 bar and 77 K is predicted as ntot= 0.085× Vp − 0.013× Vp2 for cage‐type MOFs and ntot= 0.076× Vp − 0.011× Vp2 for channel‐type MOFs, where Vp is the pore volume of corresponding MOFs. The predictions by these empirical equations are validated by several MOFs with an average deviation of 5.4%. Compared with a previous equation for activated carbon materials, the empirical equations demonstrate superior accuracy especially for MOFs with high surface area (i.e., SBET over ≈3000 m2 g−1). Guided by these empirical equations, a highly porous Zr‐MOF NPF‐200 (NPF: Nebraska Porous Framework) is examined to possess outstanding hydrogen total adsorption capacity (65.7 mmol g−1) at 77 K and record high volumetric working capacity of 37.2 g L−1 between 100 and 5 bar at 77 K.
Liquid‐Crystal‐Mediated Active Waveguides toward Programmable Integrated Optics
Authors: Wei Ting , Chen Peng , Tang Ming‐Jie , Wu Guang‐Xing , Chen Zhao‐Xian , Shen Zhi‐Xiong , Ge Shi‐Jun , Xu Fei , Hu Wei , Lu Yan‐Qing 
Published: March 2020

AbstractOptics, playing an ever‐important role in life, is developing toward miniaturization and integration. Particularly, the field programming of integrated optics will benefit its functionality and durability, thus is highly pursued. Here, through precisely controlling the space‐variant orientations of anisotropic liquid crystals (LCs), various graded‐index waveguides are demonstrated in a homogeneous medium. Straight/bending waveguides and ring resonators are fabricated via LC photopatterning. They exhibit pronounced polychromatic light‐guiding performance. Thanks to their intrinsic external‐stimuli responsivity, the thermal switchability and polarization tunability are verified. By selectively polymerizing, robust functional components and active connecting waveguides can be realized on the same chip. It provides a practical and universal solution to programmable integrated optics, and extends the applications of microstructured soft matter even in wearable photonics.
Semi‐Flooded Sulfur Cathode with Ultralean Absorbed Electrolyte in Li–S Battery
Authors: Xie Yong , Pan Guoyu , Jin Qiang , Qi Xiaoqun , Wang Tan , Li Wei , Xu Hui , Zheng Yuheng , Li Sa , Qie Long , Huang Yunhui , Li Ju 
Published: March 2020

AbstractLean electrolyte (small E/S ratio) is urgently needed to achieve high practical energy densities in Li–S batteries, but there is a distinction between the cathode's absorbed electrolyte (AE) which is cathode‐intrinsic and total added electrolyte (E) which depends on cell geometry. While total pore volume in sulfur cathodes affects AE/S and performance, it is shown here that pore morphology, size, connectivity, and fill factor all matter. Compared to conventional thermally dried sulfur cathodes that usually render “open lakes” and closed pores, a freeze‐dried and compressed (FDS‐C) sulfur cathode is developed with a canal‐capillary pore structure, which exhibits high mean performance and greatly reduces cell‐to‐cell variation, even at high sulfur loading (14.2 mg cm−2) and ultralean electrolyte condition (AE/S = 1.2 µL mg−1). Interestingly, as AE/S is swept from 2 to 1.2 µL mg−1, the electrode pores go from fully flooded to semi‐flooded, and the coin cell still maintains function until (AE/S)min ≈ 1.2 µL mg−1 is reached. When scaled up to Ah‐level pouch cells, the full‐cell energy density can reach 481 Wh kg−1 as its E/S ≈ AE/S ratio can be reduced to 1.2 µL mg−1, proving high‐performance pouch cells can actually be working in the ultralean, semi‐flooded regime.
Unraveling the Rapid Redox Behavior of Li‐Excess 3d‐Transition Metal Oxides for High Rate Capability
Authors: Jin Wooyoung , Myeong Seungjun , Hwang Jaeseong , Jang Haeseong , Sung Jaekyung , Yoo Youngshin , Kim Min Gyu , Cho Jaephil 
Published: March 2020

AbstractLi‐excess 3d‐transition metal layered oxides are promising candidates in high‐energy‐density cathode materials for improving the mileage of electric vehicles. However, their low rate capability has hindered their practical application. The lack of understanding about the redox reactions and migration behavior at high C‐rates make it difficult to design Li‐excess materials with high rate capability. In this study, the characteristics of the atomic behavior that is predominant at fast charge/discharge are investigated by comparing cation‐ordered and cation‐disordered materials using X‐ray absorption spectroscopy (XAS). The difference in the atomic arrangement determines the dominance of the transition metal/oxygen redox reaction and the variations in transition metal–oxygen hybridization. In‐depth electrochemical analysis is combined with operando XAS analysis to reveal electronically and structurally preferred atomic behavior when a redox reaction occurs between oxygen and each transition metal under fast charge/discharge conditions. This provides a fundamental insight into the improvement of rate capability. Furthermore, this work provides guidance for identifying high‐energy‐density materials with complex structural properties.
A new look at neurobehavioral development in rhesus monkey neonates (Macaca mulatta)
Authors: Paukner Annika , Capitanio John P. , Blozis Shelley A. 
Published: March 2020

AbstractThe Brazelton Neonatal Behavioral Assessment Scale (NBAS) evaluates a newborn infant's autonomic, motor, state, temperament, and social‐attentional systems, which can help to identify infants at risk of developmental problems. Given the prevalence of rhesus monkeys being used as an animal model for human development, here we aimed to validate a standardized test battery modeled after the NBAS for use with nonhuman primates called the Infant Behavioral Assessment Scale (IBAS), employing exploratory structural equation modeling using a large sample of rhesus macaque neonates (n = 1,056). Furthermore, we examined the repeated assessments of the common factors within the same infants to describe any changes in performance over time, taking into account two independent variables (infant sex and rearing condition) that can potentially affect developmental outcomes. Results revealed three factors (Orientation, State Control, and Motor Activity) that all increased over the 1st month of life. While infant sex did not have an effect on any factor, nursery‐rearing led to higher scores on Orientation but lower scores on State Control and Motor Activity. These results validate the IBAS as a reliable and valuable research tool for use with rhesus macaque infants and suggest that differences in rearing conditions can affect developmental trajectories and potentially pre‐expose infants to heightened levels of cognitive and emotional deficiencies.
Influences of passive intervertebral range of motion on cervical vertebral form
Authors: Grider‐Potter Neysa , Nalley Thierra K. , Thompson Nathan E. , Goto Ryosuke , Nakano Yoshihiko 
Published: March 2020

AbstractObjectivesThe cervical spine is the junction between the head and trunk, and it therefore facilitates head mobility and stability. The goal of this study is to test several predictions regarding cervical morphology and intervertebral ranges of motion.Materials and MethodsIntervertebral ranges of motion for 12 primate species were collected via radiographs or taken from the literature. Morphometric data describing functionally relevant aspects of cervical vertebral morphology were obtained from museum specimens representing these species. We tested for correlations between intervertebral movement and vertebral form using phylogenetic generalized least‐squares regression.ResultsResults demonstrate limited support for the hypothesis that range of motion (ROM) is influenced by cervical vertebral morphology. Few morphological variables correlate with ROM and no relationship is consistently significant across cervical joints.DiscussionThese results indicate that the relationship between vertebral morphology and joint ranges of motion is, at most, weak, providing little support the use of bony morphology to reconstruct axial mobility in fossil specimens. Future work should investigate the role of soft tissues in vertebral joint stability.
Past, present, and future of palliative care in emergency medicine in the USA
Authors: George Naomi , Bowman Jason , Aaronson Emily , Ouchi Kei 
Published: March 2020

The emergency department (ED) provides immediate access to medical care for patients and families in times of need. Increasingly, older patients with serious illness seek care in the ED, hoping for relief from symptoms and suffering associated with advanced disease. Until recently, emergency medicine (EM) clinicians have been ill‐equipped to meet the needs of patients with serious illness, and palliative services have been largely unavailable in the ED. However, in the past decade, there has been growing recognition from within both the EM and palliative medicine communities on the importance of palliative care provision in the ED. The past 10 years have seen a surge in EM–palliative care training and education, quality improvement projects, and research. As a result, the practice paradigm within EM for the seriously ill has begun to shift to incorporate more palliative care practices. Despite this progress, substantial work has yet to be done in terms of identifying ED patients in need of palliative care, training EM clinicians to provide high‐quality primary palliative care, creating pathways for ED referral to palliative care and hospice, and researching the outcomes and impact of palliative care provision on patients with serious illness in the ED.
Blood Pressure Goals and Clinical Outcomes after Successful Endovascular Therapy: A Multicenter Study
Authors: Anadani Mohammad , Arthur Adam S. , Tsivgoulis Georgios , Simpson Kit N. , Alawieh Ali , Orabi Yser , Goyal Nitin , Alexandrov Andrei V. , Maier Ilko L. , Psychogios Marios‐Nikos , Liman Jan , Brinton Daniel , Swisher Christa B. , Shah Shreyash , Inamullah Ovais , Keyrouz Salah , Kansagra Akash P. , Allen Michelle , Giles James A. , Wolfe Stacey Q. , Fargen Kyle M. , Gory Benjamin , De Marini Pierre , Kan Peter , Nascimento Fábio A. , Almallouhi Eyad , Petersen Nils , Kodali Sreeja , Rahman Shareena , Richard Sébastien , Spiotta Alejandro M. 
Published: March 2020

ObjectiveElevated systolic blood pressure (SBP) after successful revascularization (SR) via endovascular therapy (EVT) is a known predictor of poor outcome. However, the optimal SBP goal following EVT is still unknown. Our objective was to compare functional and safety outcomes between different SBP goals after EVT with SR.MethodsThis international multicenter study included 8 comprehensive stroke centers and patients with anterior circulation large vessel occlusion who were treated with EVT and achieved SR. SR was defined as modified thrombolysis in cerebral ischemia 2b to 3. Patients were divided into 3 groups based on SBP goal in the first 24 hours after EVT. Inverse probability of treatment weighting (IPTW) propensity analysis was used to assess the effect of different SBP goals on clinical outcomes.ResultsA total of 1,019 patients were included. On IPTW analysis, the SBP goal of <140mmHg was associated with a higher likelihood of good functional outcome and lower odds of hemicraniectomy compared to SBP goal of <180mmHg. Similarly, SBP goal of <160mmHg was associated with lower odds of mortality compared to SBP goal of <180mmHg. In subgroup analysis including only patients with pre‐EVT SBP of ≥140mmHg, an SBP of <140mmHg was associated with a higher likelihood of good functional outcome, lower odds of symptomatic intracranial hemorrhage, and lower odds of requirement for hemicraniectomy compared to SBP goal of <180mmHg.InterpretationSBP goals of <140 and < 160mmHg following SR with EVT appear to be associated with better clinical outcomes than SBP of <180mmHg. ANN NEUROL 2020;87:830–839