bluuebunny/crossref_metadata_2025_split huggingface dataset:
More than therapy: The link between adverse childhood experiences, social support, and therapeutic services
Authors: Ronnenberg Megan , Conrad Aislinn , Wojciak Armeda Stevenson , Menninga Elizabeth 
Published: February 2020

AbstractAdverse childhood experiences (ACEs) have a cumulative effect on physical, emotional, and social well‐being throughout the life course. ACEs also impact parenting practices, which may contribute to intergenerational cycles of trauma. Access to child mental health services and caregiver social support are two protective factors that may reduce the burden of ACEs. To advance understanding of the relationships between caregiver social support and child mental health services among caregivers with ACEs, we interviewed 13 caregivers of young children receiving outpatient mental health services. Thematic analysis revealed the integral role of therapeutic providers in the social support circles of caregivers with high ACE scores. Caregivers frequently named therapeutic providers as the first point of contact in a problem situation. Implications for social work research, clinical practice, and advocacy are discussed.
Five lessons to guide more effective biodiversity conservation message framing
Authors: Kusmanoff Alexander M. , Fidler Fiona , Gordon Ascelin , Garrard Georgia E. , Bekessy Sarah A. 
Published: February 2020

AbstractCommunication and advocacy approaches that influence attitudes and behaviors are key to addressing conservation problems, and the way an issue is framed can affect how people view, judge, and respond to an issue. Responses to conservation interventions can also be influenced by subtle wording changes in statements that may appeal to different values, activate social norms, influence a person's affect or mood, or trigger certain biases, each of which can differently influence the resulting engagement, attitudes, and behavior. We contend that by strategically considering how conservation communications are framed, they can be made more effective with little or no additional cost. Key framing considerations include, emphasizing things that matter to the audience, evoking helpful social norms, reducing psychological distance, leveraging useful biases, and, where practicable, testing messages. These lessons will help communicators think strategically about how to frame messages for greater effect.
Positioning human heritage at the center of conservation practice
Authors: Montgomery Robert A. , Borona Kendi , Kasozi Herbert , Mudumba Tutilo , Ogada Mordecai 
Published: February 2020

AbstractConservation projects subscribing to a community‐based paradigm have predominated in the 21st century. We examined the context in which the phrase was coined and traced its growth over time.Community‐based conservationfirst appeared in the literature in the early 1990s; but grew little until after the 5th World Parks Congress in 2003. Thereafter, publications describing community‐based conservation approaches increased exponentially. The conference theme was Benefits Beyond Boundaries, and its goal was to provide an economic model based on revenue accrued from conservation fundraising and ecotourism to support ecosystems, wildlife, and people, particularly in the Global South. Such models tended not to incorporate, as a core principle, the heritage of local human communities. Human heritage varies substantially over time and space making generalization of conservation principles across scales challenging. Pitfalls that have grown out of the community‐based conservation approaches in the Global South include fortress conservation, conservation militarism, consumptive and nonconsumptive ecotourism, and whiz‐bang solutions. We propose 10 tenets in a human heritage‐centered conservation framework (e.g., engage in conservation practices using local languages, thoughtfully propose and apply solutions consistent with human heritage, provide clear professional development pathways for individuals from local communities, and promote alternative revenue‐generating programs centered in local communities, among others). Progressive philosophies can derive from authentic and ethical integration of local communities in conservation practice.
Management strategies for patients with advanced rectal cancer and liver metastases using modified Delphi methodology: results from the PelvEx Collaborative
Authors:   PelvEx Collaborative
Published: February 2020

AbstractAimA total of 15–20% of patients with rectal cancer have liver metastases on presentation. The management of these patients is controversial. Heterogeneity in management strategies is considerable, with management often being dependent on local resources and available expertise.MethodMembers of the PelvEx Collaborative were invited to participate in the generation of a consensus statement on the optimal management of patients with advanced rectal cancer with liver involvement. Fifteen statements were created for topical discussion on diagnostic and management issues. Panellists were asked to vote on statements and anonymous feedback was given. A collaborative meeting was used to discuss any nuances and clarify any obscurity. Consensus was considered when > 85% agreement on a statement was achieved.ResultsA total of 135 participants were involved in the final round of the Delphi questionnaire. Nine of the 15 statements reached consensus regarding the management of patients with advanced rectal cancer and oligometastatic liver disease. Routine use of liver MRI was not recommended for patients with locally advanced rectal cancer, unless there was concern for metastatic disease on initial computed tomography staging scan. Induction chemotherapy was advocated as first‐line treatment in those with synchronous liver metastases in locally advanced rectal cancer. In the presence of symptomatic primary disease, a diverting stoma may be required to facilitate induction chemotherapy. Overall, only one‐quarter of the panellists would consider simultaneous pelvic exenteration and liver resection.ConclusionThis Delphi process highlights the diverse treatment of advanced rectal cancer with liver metastases and provides recommendations from an experienced international group regarding the multidisciplinary management approach.
The effectiveness, safety and compliance of Zheng’s supine rehabilitation exercise as a rehabilitation programme among elderly patients with AECOPD
Authors: Lu Haonan , Liu Ni , Hu Jie Ying , Wang Xinni , Li Youxia , Song Mali , Zhong Li Hong , He Wei , Chen RongChang , Zheng Zeguang 
Published: February 2020

AbstractPurposeWe investigated the effectiveness, safety and compliance of Zheng’s Supine Rehabilitation Exercise (ZSRE) as a rehabilitation programme among elderly patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Patients and methodsAbout 82 elderly patients with AECOPD were divided into a rehabilitation group and control group on their admission day, and both groups received routine medical treatment. Patients in the rehabilitation group started ZSRE on the second day of admission and continued until 8 weeks after discharge.ResultsAt the 9th week after discharge, the COPD Assessment Test (CAT), 6‐minute walking distance (6MWD) and Modified Medical Research Council Dyspnea Scale (mMRC) in the rehabilitation group were all significantly better than those in the control group (P < 0.01; P < 0.01; and P < 0.05, respectively). In the rehabilitation group, the CAT and 6MWD were significantly improved in the 9th week after discharge as compared with those at admission or discharge, and mMRC was significantly improved at the 9th week after discharge as compared with that at admission (all P < 0.01).ConclusionZSRE can be performed by elderly patients with the acute exacerbation of severe or extremely severe COPD with high safety and compliance and was helpful for their recovery.
Omiganan Enhances Imiquimod‐Induced Inflammatory Responses in Skin of Healthy Volunteers
Authors: Niemeyer‐van der Kolk Tessa , Assil Salma , Buters Thomas P. , Rijsbergen Melanie , Klaassen Erica S. , Feiss Gary , Florencia Edwin , Prens Errol P. , Burggraaf Jacobus , van Doorn Martijn B.A. , Rissmann Robert , Moerland Matthijs 
Published: February 2020

Omiganan (OMN; a synthetic cationic peptide) and imiquimod (IMQ; a TLR7 agonist) have synergistic effects on interferon responses in vitro. The objective of this study was to translate this to a human model for proof‐of‐concept, and to explore the potential of OMN add‐on treatment for viral skin diseases. Sixteen healthy volunteers received topical IMQ, OMN, or a combination of both for up to 4 days on tape‐stripped skin. Skin inflammation was quantified by laser speckle contrast imaging and 2D photography, and molecular and cellular responses were analyzed in biopsies. IMQ treatment induced an inflammatory response of the skin. Co‐treatment with OMN enhanced this inflammatory response to IMQ, with increases in perfusion (+17.1%; 95% confidence interval (CI) 5.6%–30%; P < 0.01) and erythema (+1.5; 95% CI 0.25%–2.83; P = 0.02). Interferon regulatory factor‐driven and NFκB‐driven responses following TLR7 stimulation were enhanced by OMN (increases in IL‐6, IL‐10, MXA, and IFNɣ), and more immune cell infiltration was observed (in particular CD4+, CD8+, and CD14+ cells). These findings are in line with the earlier mechanistic in vitro data, and support evaluation of imiquimod/OMN combination therapy in human papillomavirus‐induced skin diseases.
Quantifying the coherence of development policy priorities
Authors: Guerrero Omar A. , Castañeda Gonzalo 
Published: February 2020

AbstractMotivationOver the last 30 years, the concept of policy coherence for development has attracted the attention of academics, practitioners and international organizations. However, its quantification and measurement remain elusive.Research questionsTo address this challenge, we develop a quantitative counterfactual‐based framework to measure the coherence of policy priorities for development.Approach of methodsOur framework takes account of the country‐specific constraints facing governments in trying to reach development goals. We present a new definition of policy coherence that employs resource allocations as the baseline to construct a coherence index.ResultsWe validate this coherence index by producing country‐specific estimates that are consistent with well‐known cases of development strategies, both successful and failed.ConclusionsOur results highlight the limitations of assessing coherence in terms of benchmark comparisons using development‐indicator data. Our framework sheds new light in a promising direction to develop bespoke analytic tools to meet the 2030 Agenda.
Right coronary artery–right ventricular fistula complicated with infective endocarditis
Authors: Duan ShaSha , Shi YiLu , Zhang XiaoShan , Li ShuJuan , Sun ZhenTing 
Published: February 2020

AbstractCoronary artery fistula (CAF) is a congenital disease in which a communication forms between one or more coronary arteries and a cardiac chamber or great vessel. We describe an infrequent case of right coronary artery (RCA) fistula into the right ventricle (RV) complicated by infective endocarditis in a child. The patient received echocardiography and contrast‐enhanced multidetector computed tomography (MDCT). Surgical treatment was performed after management of the infection. Unfortunately, a residual fistula formed after surgery. However, interestingly, the residual fistula spontaneously resolved at one year after surgery. He is now in good condition and totally asymptomatic.
Exploring Heterogeneities with Geographically Weighted Quantile Regression: An Enhancement Based on the Bootstrap Approach
Authors: Chen Vivian Yi‐Ju , Yang Tse‐Chuan , Matthews Stephen A. 
Published: February 2020

Geographically weighted quantile regression (GWQR) has been proposed as a spatial analytical technique to simultaneously explore two heterogeneities, one of spatial heterogeneity with respect to data relationships over space and one of response heterogeneity across different locations of the outcome distribution. However, one limitation of GWQR framework is that the existing inference procedures are established based on asymptotic approximation, which may suffer computation difficulties or yield incorrect estimates with finite samples. In this article, we suggest a bootstrap approach to address this limitation. Our bootstrap enhancement is first validated by a simulation experiment and then illustrated with an empirical U.S. mortality data. The results show that the bootstrap approach provides a practical alternative for inference in GWQR and enhances the utilization of GWQR.
Designing high‐performance colour cosmetics through optimization of powder flow characteristics
Authors: Liu X. , Drakontis C. , Amin S. 
Published: February 2020

AbstractObjectiveExplore the impact of powder flow properties such as flow energy and compressibility on the performance characteristics of foundation powders such as cake strength and pay‐off.MethodsFT4 Powder Rheometer from Freeman Technology was utilized to explore various powder compositions. The three major tests performed were flowability test, compressibility test and shear cell test.ResultsThe results highlight that the sample which has higher compressibility has the better cake strength, and the sample which requires lower total energy has better pay‐off. Particles or samples with lower total flow energy, should have easier flow, therefore, should have better pay‐off. Samples and components with higher compressibility, should hold the structure better, therefore, should have better cake strength. Talc has the highest compressibility and lowest flow energy. Foundation sample 5 has the highest concentration of talc and also has the best performance.ConclusionThe lower the total flow energy, the easier it is for the powder to flow, and have better pay‐off. Powder compressibility correlates with cake strength which means that a sample with better compressibility consequently has the better cake strength. Samples 5 and 10 require less total flow energy, have lower shear stress, and higher compressibility, therefore, have better final performance. Both samples 5 and 10 have higher talc concentrations compared to other formulations.
Biological dermal templates with native collagen scaffolds provide guiding ridges for invading cells and may promote structured dermal wound healing
Authors: Dill Veronika , Mörgelin Matthias 
Published: February 2020

AbstractDermal substitutes are of major importance in treating full thickness skin defects. They come in a variety of materials manufactured into various forms, such as films, hydrocolloids, hydrogels, sponges, membranes, and electrospun micro‐ and nanofibers. Bioactive dermal substitutes act in wound healing either by delivery of bioactive compounds or by being constructed from materials having endogenous activity. The healing success rate is highly determined by cellular and physiological processes at the host‐biomaterial interface during crucial wound healing steps. Hence, it is important to design appropriate wound treatment strategies with the ability to work actively with tissues and cells to enhance healing. Therefore, in this study, we investigated biological dermal templates and their potential to stimulate natural cell adherence, guidance, and morphology. The most pronounced effect was observed in biomaterials with the highest content of native collagen networks. Cell attachment and proliferation were significantly enhanced on native collagen scaffolds. Cell morphology was more asymmetrical on such scaffolds, resembling native in vivo structures. Importantly, considerably lower expression of myofibroblast phenotype was observed on native collagen scaffolds. Our data suggest that this treatment strategy might be beneficial for the wound environment, with the potential to promote improved tissue regeneration and reduce abnormal scar formation.
Paternal mental health during the perinatal period: A qualitative systematic review
Authors: Shorey Shefaly , Chan Valerie 
Published: February 2020

AbstractAimsTo examine fathers’ experiences and needs associated with mental health during the perinatal period.DesignQualitative studies were meta‐synthesized using the steps outlined by Sandelowski and Barroso.Data sourcesSix databases (PubMed, Embase, PsycINFO, CINAHL, Scopus and ProQuest) were searched for qualitative studies from each database's inception to 24 June 2019.Review methodsStudies were critically appraised using the Critical Appraisal Skills Program tool. Qualitative data were extracted, meta‐summarized, then meta‐synthesized.ResultsFourteen studies were included and four themes were identified: (a) negative feelings and psychological difficulties, (b) role strain and role conflict with multiple sources, (c) coping strategies that buffered negative feelings and psychological difficulties and (d) support needs to enhance mental health.ConclusionFathers reported poor mental health and expressed needs to enhance their mental health across the perinatal period. Future studies can focus specifically on paternal mental health. The development of theory‐guided, family inclusive, technology‐based healthcare services are needed to manage mental health. Healthcare providers can promote positive mental health to prepare fathers, increasing their awareness to manage their mental health and to seek timely help.ImpactProblem‐focused coping (i.e. support and problem‐solving with partners and childcare involvement) helped fathers to buffer their negative feelings and psychological difficulties. Future studies should focus on paternal mental health rather than on general fathering experiences. Healthcare providers should focus on promoting positive mental health and well‐being. Policymakers should create awareness on paternal mental health across the perinatal period.
Fate of Listeria on various food contact and noncontact surfaces when treated with bacteriophage
Authors: Reinhard Robert G. , Kalinowski Robin M. , Bodnaruk Peter W. , Eifert Joseph D. , Boyer Renee R. , Duncan Susan E. , Bailey R. Hartford 
Published: February 2020

AbstractStudy objective was to determine efficacy of a bacteriophage suspension against Listeria spp. when applied to three common types of materials used in food manufacturing facilities. Materials included two food contact materials (stainless steel and polyurethane thermoplastic belting) and one noncontact material (epoxy flooring). Coupons of each material were inoculated with a cocktail containing L. monocytogenes and L. innocua (4 to 5‐log10 CFU/cm2). Two phage concentrations and a control, 0, 2 × 107 and 1 × 108 PFU/cm2 were evaluated. Treated samples were held at 4 or 20°C for 1 and 3 hr to determine the effect of temperature and treatment time. Reductions in Listeria populations ranged from 1.27 to 3.33 log10 CFU/cm2 on stainless steel, from 1.17 to 2.76 log10 CFU/cm2 on polyurethane thermoplastic belting, and from 1.19 to 1.76 log10 CFU/cm2 on epoxy resin flooring. Higher phage concentration (1 × 108 PFU/cm2), longer treatment time (3 hr), and processing area temperature of 20°C showed a greater (p ≤ .05) reduction of Listeria on the stainless‐steel and polyurethane thermoplastic belting coupons. Overall, Listeria reduction by phage treatment occurred on all three materials tested, under all conditions.
Improving Glycemic Control in African Americans With Diabetes and Mild Cognitive Impairment
Authors: Rovner Barry W. , Casten Robin J. , Piersol Catherine Verrier , White Neva , Kelley Megan , Leiby Benjamin E. 
Published: February 2020

BACKGROUND/OBJECTIVESImproving glycemic control in older African Americans with diabetes and mild cognitive impairment (MCI) is important as the population ages and becomes more racially diverse.DESIGNRandomized controlled trial.SETTINGRecruitment from primary care practices of an urban academic medical center. Community‐based treatment delivery.PARTICIPANTSOlder African Americans with MCI, low medication adherence, and poor glycemic control (N = 101).INTERVENTIONSOccupational therapy (OT) behavioral intervention and diabetes self‐management education.MEASUREMENTSThe primary outcome was a reduction in hemoglobin A1c level of at least 0.5% at 6 months, with maintenance effects assessed at 12 months.RESULTSAt 6 months, 25 of 41 (61.0%) OT participants and 22 of 46 (48.2%) diabetes self‐management education participants had a reduction in hemoglobin A1c level of at least 0.5%. The model‐estimated rates were 58% (95% confidence interval [CI] = 45%‐75%) and 48% (95% CI = 36%‐64%), respectively (relative risk [RR] = 1.21; 95% CI = 0.84‐1.75; P = .31). At 12 months, the respective rates were 21 of 39 (53.8%) OT participants and 24 of 49 (49.0%) diabetes self‐management education participants. The model‐estimated rates were 50% (95% CI = 37%‐68%) and 48% (95% CI = 36%‐64%), respectively (RR = 1.05; 95% CI = 0.70‐1.57; P = .81).CONCLUSIONBoth interventions improved glycemic control in older African Americans with MCI and poor glycemic control. This result reinforces the American Diabetes Associationʼs recommendation to assess cognition in older persons with diabetes and demonstrates the potential to improve glycemic control in this high‐risk population. J Am Geriatr Soc 68:1015–1022, 2020
Retrospective photographic review of nontattoo indications treated by picosecond laser
Authors: Mehrabi Joseph N. , Friedman Or , Al‐Niaimi Firas , Artzi Ofir 
Published: February 2020

AbstractBackgroundPicosecond (PS) lasers were approved by the US FDA in 2012 after being shown to remove tattoos with more success and fewer treatments compared with traditional methods. PS lasers were shown to be versatile, indicated for the treatment of lentigines, café‐au‐lait macules (CALMs), and acne scars and skin rejuvenation.ObjectiveWe report our experience treating our patients for different indications using a PS laser.MethodsWe performed a retrospective chart and photographic review of all patients seen between 2016 and 2018 that were treated in our centers with a PS laser for nontattoo indications. Clinical outcomes were evaluated using side‐by‐side comparisons of the clinical photographs by two blinded, independent physicians using a visual analog scale consisting of six levels of treatment response.ResultsA total of 233 patients were studied. Most sought treatment for solar lentigo (27%) and skin rejuvenation (14%). Epidermal nevi exhibited the greatest improvement with treatment, while acne scarring demonstrated the least. Only 24% of patients experienced noteworthy, transient adverse effects.ConclusionPicosecond lasers were efficacious and safe for a variety of indications. They were effective in treating epidermal nevi and pigmented lesions, such as Lentigines and CALMs.