bluuebunny/crossref_metadata_2025_split huggingface dataset:
Title IX
Authors: Carpenter Linda Jean , Acosta R. Vivian 
Published: April 2020

Title IX delivers a complete look at one of sport's critical gender equity issues. It goes beyond intercollegiate athletics to address Title IX in the context of sport, physical activity, recreation, intramurals, and physical education. From its enactment in 1972, Title IX has been often oversimplified or misunderstood by both advocates and critics of the legislation. Knowledgeable in the legal issues of sport and experienced in the administration of sport and physical education programs, the authors of Title IX offer a balanced, comprehensive view of this issue, lending important insights into Title IX's requirements and application both now and when it was enacted.
Title IX, the law, prohibits any education program or activity receiving federal financial assistance from discriminating on the basis of sex. Title IX, the text, helps to clarify the law in a three-part progression that is accurate and accessible. In Part I, you will see Title IX's structure and requirements applied in different settings including physical education, intramurals and recreation, and athletics. Part II then provides a historical account of the social, legislative, and judicial environments in which Title IX has grown to maturity over the past three decades. Finally, part III examines Title IX in the 21st century, its impact on sport related programs, and continuing debates.
Title IX will also help you gain a solid understanding of the law itself. You will examine the actual wording of the law and related interpretive materials. You'll review significant lawsuits as you explore how the legislation has been interpreted and judicially clarified over the years in changing social and political climates. You'll find further clarifying information in summaries and questions and answers at the end of each chapter. Six appendixes provide pertinent excerpts from Title IX regulations, policy interpretations, letters of clarification, and an annotated list of other print and online resources. Whether you're looking for clarification of Title IX or for information on applying it in your programs, you'll find the information you need in Title IX.
Foundations of Wellness
Authors: Reger-Nash Bill , Smith Meredith , Juckett Gregory 
Published: April 2020

Life is crammed with busyness, screen time, and an abundance of shallow experiences. If you don't mindfully change your way of thinking and behaving, that's all your life will ever be.
Foundations of Wellness can help you live a satisfying life—one full of rich and deep experiences. You’ll understand your identity and inner strengths and resources as well as set and move toward meaningful personal goals.
With Foundations of Wellness, you will explore physical, mental, emotional, social, environmental, and spiritual realms of wellness using an evidence-based approach to health and wellness that will help you explore ways to live your life to the fullest. You will examine the seven attitudinal foundations of mindfulness to daily living, delve into wellness resources and dietary needs, discover health check strategies, and learn the keys to making healthy behavioral changes.
Foundations of Wellness is written in a conversational style and divided into three parts. Part I establishes basic wellness problems and introduces tools to discovering wellness and inner peace. Part II addresses physical dimensions of wellness, including physical activity, nutrition, sleep, and body maintenance. In part III you’ll discover the strategies that will propel you to a higher level of living—one that can affect not only your life but also the lives of others for generations to come.
Each chapter explores key concepts and topics that affect your wellness. The chapters begin with objectives and a vignette that illustrates a challenge related to the content and use stories to illustrate teaching points. The text also incorporates activity sidebars that empower you to make the behavioral changes that will lead to a more satisfying and meaningful life.
You will learn how to incorporate mindfulness—a practice that helps you live with greater awareness—and positive psychology as you embark on your wellness journey. In Foundations of Wellness, you will also learn the seven attitudinal foundations of mindfulness practices and explore the spiritual truths that are at the core of wellness.
Comparison of GTO-ECV and adjusted MERRA-2 total ozone columns from the last 2 decades and assessment of interannual variability
Authors: Coldewey-Egbers Melanie , Loyola Diego G. , Labow Gordon , Frith Stacey M. 
Published: April 2020

Abstract. In this study we compare the satellite-based Global Ozone Monitoring Experiment (GOME)-type Total Ozone Essential Climate
Variable (GTO-ECV) record, generated as part of the European Space Agency's Climate
Change Initiative (ESA-CCI) ozone project, with the adjusted total ozone product from
the Modern Era Retrospective Analysis for Research and Applications version 2 (adjusted MERRA-2)
reanalysis, produced at the National Aeronautics and Space Administration (NASA) Global
Modeling and Assimilation Office (GMAO). Total ozone columns and associated standard
deviations show a very good agreement in terms of both spatial and temporal patterns
during their 23-year overlap period from July 1995 to December 2018. The mean difference
between adjusted MERRA-2 and GTO-ECV 5∘×5∘ monthly mean total ozone
columns is -0.9±1.5 %. A small discontinuity in the deviations is detected in October 2004, when data from the Ozone Monitoring Instrument (OMI) were ingested in the GTO-ECV
and adjusted MERRA-2 data records. This induces a small overall negative drift in the differences for almost all
latitude bands, which, however, does not exceed 1 % per decade. The mean difference for
the period prior to October 2004 is -0.5±1.7 %, whereas the difference is -1.0±1.1 %
for the period from October 2004 to December 2018. The variability in the differences is
considerably reduced in the period after 2004 due to a significant increase in data coverage
and sampling. In the tropical region, the differences indicate a slight zonal variability with
negative deviations over the Atlantic, Africa, and the Indian Ocean and positive deviations
over the Pacific. Ozone anomalies and the distribution of their statistical moments indicate
a very high correlation among both data records as to the temporal and spatial structures.
Furthermore, we evaluate the consistency of the data sets by means of an empirical orthogonal
function (EOF) analysis. The interannual variability is assessed in the tropics, and both
GTO-ECV and adjusted MERRA-2 exhibit a remarkable agreement with respect to the derived patterns.
The first four EOFs can be attributed to different modes of interannual climate variability,
and correlations with the Quasi-Biennial Oscillation (QBO), the El Niño–Southern Oscillation
(ENSO) signal, and the solar cycle were found.
Imitación de la poesía de Rubén Darío o el apócrifo del discurso aglutinante como estrategia de escritura de Manuel Mantero
Authors: Campos Ruiz Ignacio 
Published: April 2020

Este trabajo interpreta un poema de Manuel Mantero titulado “Para Antonio Machado, en contestación a su poema ‘Al maestro Rubén Darío’, texto que durante un lapso de tiempo circuló simulando ser del nicaragüense universal. En este poema-homenaje Mantero hizo converger tanto la poética machadianacomo la dariana, además de la tradición española, en una formulación creativa de la imitación en el cont exto de 1967.
Een kritisch-pragmatische bestuurskunde
Authors: Metze Tamara 
Published: April 2020

A critical-pragmatist public administration
A pragmatic criticaster or a critical pragmatist is considered a schizophrenic in daily life: it seems impossible to be solution oriented and critical at the same time. You are either an optimist or a pessimist. This schism also seems to run between public administration and political scientists. Public administration is focused on (positive) problem solving, whereas political scientists – especially in a tradition of critical theory – examine the exertion of power. This essay proposes a combination of the two extremes: a critical-pragmatist approach for public administration.In this approach, critical political theory goes hand in hand with pragmatist reconstruction and design. This design is impossible without normative and procedural principles, for example ideas about sustainability, justice and democracy. This is illustrated with an example for designing just governance arrangements in the Dutch regional energy strategies. The article shows that public administration that is relevant, reflective and democratic builds on a critical-pragmatist approach.
The Long-term Characteristics of PM10 and PM2.5 in Bangkok, Thailand
Authors: Chirasophon Supanan , Pochanart Pakpong 
Published: April 2020

Abstract
The long-term characteristics of non-roadside (residential) PM10 and PM2.5 in Bangkok, Thailand was analyzed by using hourly concentrations of PM10 and PM2.5 which had been collected from 10 monitoring stations by the Pollution Control Department (PCD) of Thailand from 2006 to 2016. The results showed that most of the stations showed either the decreasing trend or no trend characters. The PM2.5 and PM10 during weekdays and dry season were higher than during weekends and wet season, respectively. The diurnal variations of both PM2.5 and PM10 exhibited multi-peaks characteristic, mostly 2 peaks during a day for PM2.5 and 2 to 3 peaks depending on the locations for PM10. The PM2.5 to PM10 ratio of our residential monitoring stations was 0.61 in average which was in the same range as the PM2.5/PM10 ratio from the roadside monitoring stations. This shows that the common sources of PM2.5 and PM10 at both types of monitoring station were similar, probably mainly from the traffic and transportations. However, it was found that PM2.5/PM10 ratio during wet season was lower than during dry season indicating the role of emission sources and removal process in each season.
Fish and fisheries in hot water: What is happening and how do we adapt?
Authors: Pinsky Malin L. , Fenichel Eli , Fogarty Michael , Levin Simon , McCay Bonnie , St. Martin Kevin , Selden Rebecca L. , Young Talia 
Published: April 2020

AbstractRapid climate changes are currently driving substantial reorganizations of marine ecosystems around the world. A key question is how these changes will alter the provision of ecosystem services from the ocean, particularly from fisheries. To answer this question, we need to understand not only the ecological dynamics of marine systems, but also human adaptation and feedbacks between humans and the rest of the natural world. In this review, we outline what we have learned from research primarily in continental shelf ecosystems and fishing communities of North America. Key findings are that marine animals are highly sensitive to warming and are responding quickly to changes in water temperature, and that such changes are often happening faster than similar processes on land. Changes in species distributions and productivity are having substantial impacts on fisheries, including through changing catch compositions and longer distances traveled for fishing trips. Conflicts over access to fisheries have also emerged as species distributions are no longer aligned with regulations or catch allocations. These changes in the coupled natural‐human system have reduced the value of ecosystem services from some fisheries and risk doing so even more in the future. Going forward, substantial opportunities for more effective fisheries management and operations, marine conservation, and marine spatial planning are likely possible through greater consideration of climate information over time‐scales from years to decades.
Sol–Gel‐Based Advanced Porous Silica Materials for Biomedical Applications
Authors: Lei Qi , Guo Jimin , Noureddine Achraf , Wang Aixia , Wuttke Stefan , Brinker C. Jeffrey , Zhu Wei 
Published: April 2020

AbstractPorous silica‐based materials have burgeoning applications ranging from fillers and additives, to adsorbents, catalysts, and recently therapeutic agents and vaccines in nanomedicine. The preponderance of these materials is made by sol–gel processing wherein soluble silica precursors are reacted to form amorphous networks composed of siloxane bonds. The facile sol–gel approach allows for an unlimited variety of binary tertiary and more complex chemical compositions including organic ligands and networks resulting in so‐called organic–inorganic hybrid materials. Here, a brief review of the recent progress in sol–gel‐derived silica materials prepared as particles, thin films, biosilica/silica bioreplicas (of molecules, cells and organisms), and their related preparation, properties, and bioapplications is provided. First, it highlights the recent achievements of mesoporous silica nanoparticles in biomedical applications, including therapeutic agent delivery, multimodal imaging and theranostics, and bone tissue engineering and repair. Second, the research in evaporation‐induced self‐assembly (EISA)‐based mesostructured silica thin films and cell‐directed EISA in bio/nano interfaces for various bioapplications, such as bioactive coatings, biosensing, and living cell immobilization, has been reviewed. Third, the pioneering work in biomimetic silicification/immobilization of biomolecules and bio‐organisms and silica bioreplication of complex bio‐organisms is summarized. Finally, it is concluded with personal perspectives on the directions of future work on this field.
A Transparent, Wearable Fluorescent Mouthguard for High‐Sensitive Visualization and Accurate Localization of Hidden Dental Lesion Sites
Authors: Li Xuemeng , Luo Chongdai , Fu Quanying , Zhou Cuiping , Ruelas Marina , Wang Yingshuting , He Jinxu , Wang Yangyang , Zhang Yu Shrike , Zhou Jianhua 
Published: April 2020

AbstractAccurate detection and early diagnosis of oral diseases such as dental caries and periodontitis, can be potentially achieved by detecting the secretion of volatile sulfur compounds (VSCs) in oral cavities. Current diagnostic approaches for VSCs can detect the existence and concentrations, yet are not capable of locating the dental lesion sites. Herein, the development of a unique approach for accurately locating dental lesion sites using a fluorescent mouthguard consisting of the zinc oxide–poly(dimethylsiloxane) (ZnO‐PDMS) nanocomposite to detect the local release of VSCs is reported. The ZnO‐PDMS mouthguard displays a highly sensitive and selective response to VSCs, and exhibits high fluorescent stability, good biocompatibility, and low biological toxicity in normal physiological environments. Then, the wearable ZnO‐PDMS mouthguard is demonstrated to be able to identify the precise locations of lesion sites in human subjects. Combined with image analysis, the mouthguards successfully uncover the precise locations of dental caries, allowing convenient screening of hidden dental lesion sites that are oftentimes omitted by dentists. Due to low cost, long‐term stability, and good patient compliance, the proposed wearable mouthguard is suitable for large‐scale production and enables widely applicable, preliminary yet accurate screening of dental lesions prior to dental clinics and routine physical examinations.
Simultaneously Achieving Ultrahigh Sensitivity and Wide Detection Range for Stretchable Strain Sensors with an Interface‐Locking Strategy
Authors: Lin Waner , He Chubin , Huang Huayi , Zhao Wenyu , Qiu Yanbing , Guan Xiao , Zhang Qi , Wang Ziya , Peng Zhengchun 
Published: April 2020

AbstractThe development of stretchable strain sensors is crucial for the implementation of electronic skins and wearable electronics. Resistive‐type strain sensors are typically composed of an electrically conductive sensing layer coupled to a stretchable substrate. When a sensor is stretched, microstructural changes in the sensing layer lead to a strain‐dependent change in resistance. However, strain sensors with high sensitivity and specificity often suffer from a limited detection range along with reliability issues. Here, a novel strain sensor composed of Ag particles and long‐range entangled carbon nanotubes (CNTs) with a special composite design is proposed, in which a strain‐induced self‐locking effect is introduced at the interface between the CNT film and a percolating network consisting of Ag particle filler. As a result, the sensors achieve significantly enhanced performance such as large stretchability (≥120%), high gauge factor (3990.8), fast response time (<33 ms), and high mechanical durability. A range of wearable applications including radial artery, facial expression, and joint motion monitoring are demonstrated, which range from minute deformation to excessive stretching of the sensor.
Catalytic Asymmetric Halohydroxylation of α,β‐Unsaturated Ketones with Water as the Nucleophile
Authors: Li Weiwei , Zhou Pengfei , Li Gonglin , Lin Lili , Feng Xiaoming 
Published: April 2020

AbstractThe catalytic asymmetric halohydroxylation of α,β‐unsaturated ketones with water as the nucleophile has been realized by applying a chiral N,N′‐dioxide/Fe(OTf)2 complex as the catalyst. Bromo‐, chloro‐ and iodo‐hydroxylations were all suitable in this catalytic system. A variety of α‐halo‐β‐hydroxy ketones were obtained in often good yields with generally high dr and ee values. Besides, a Michael/α‐halogenation process was considered more possible and a possible transition state model was proposed to explain the origin of stereoselectivity.magnified image
Efficacy of venetoclax in high risk relapsed mantle cell lymphoma (MCL) ‐ outcomes and mutation profile from venetoclax resistant MCL patients
Authors: Zhao Shuangtao , Kanagal‐Shamanna Rashmi , Navsaria Lucy , Ok Chi Young , Zhang Shaojun , Nomie Krystle , Han Guangchun , Hao Dapeng , Hill Holly A. , Jiang Changying , Yao Yixin , Nastoupil Loretta , Westin Jason , Fayad Luis , Nair Ranjit , Steiner Raphel , Ahmed Sairah , Samaniego Felipe , Iyer Swaminathan P. , Oriabure Onyeka , Chen Wendy , Song Xingzhi , Zhang Jianhua , Badillo Maria , Moghrabi Omar , Aranda Jorge , Tang Guilin , Yin C. Cameron , Patel Keyur , Medeiros Leonard Jeffrey , Li Shaoying , Vega Francisco , Thirumurthi Selvi , Xu Guofan , Neelapu Sattva , Flowers Christopher R. , Romaguera Jorge , Fowler Nathan , Wang Linghua , Wang Michael L. , Jain Preetesh 
Published: April 2020

AbstractVenetoclax is effective in relapsed patients with mantle cell lymphoma (MCL). Mechanisms of resistance to venetoclax in MCL are poorly understood. We describe the clinical outcomes and genomic characteristics of 24 multiply relapsed patients (median of five prior lines of therapy) who received venetoclax‐based therapies; 67% had progressed on BTK inhibitors (BTKi) and 54% had blastoid or pleomorphic histology. Median follow up after venetoclax treatment was 17 months. The overall response rate was 50% and complete response (CR) rate was 21%, 16 patients had progressed and 15 died. The median progression free, overall and post venetoclax survival were 8, 13.5 and 7.3 months respectively. Whole‐exome sequencing (WES) was performed on samples collected from seven patients (including five pairs; before starting venetoclax and after progression on venetoclax). The SMARCA4 and BCL2 alterations were noted only after progression, while TP53, CDKN2A, KMT2D, CELSR3, CCND1, NOTCH2 and ATM were altered 2‐4‐fold more frequently after progression. In two patients with serial samples, we demonstrated clonal evolution of novel SMARCA4 and KMT2C/D mutations at progression. Mutation dynamics in venetoclax resistant MCL is demonstrated. Our data indicates that venetoclax resistance in MCL is predominantly associated with non‐BCL2 gene mutations. Further studies are ongoing in MCL patients to evaluate the efficacy of venetoclax in combination with other agents and understand the biology of venetoclax resistance in MCL.
Left Prefrontal Connectivity Links Subthalamic Stimulation with Depressive Symptoms
Authors: Irmen Friederike , Horn Andreas , Mosley Philip , Perry Alistair , Petry‐Schmelzer Jan Niklas , Dafsari Haidar S. , Barbe Michael , Visser‐Vandewalle Veerle , Schneider Gerd‐Helge , Li Ningfei , Kübler Dorothee , Wenzel Gregor , Kühn Andrea A. 
Published: April 2020

ObjectiveSubthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD) not only stimulates focal target structures but also affects distributed brain networks. The impact this network modulation has on non‐motor DBS effects is not well‐characterized. By focusing on the affective domain, we systematically investigate the impact of electrode placement and associated structural connectivity on changes in depressive symptoms following STN‐DBS, which have been reported to improve, worsen, or remain unchanged.MethodsDepressive symptoms before and after STN‐DBS surgery were documented in 116 patients with PD from 3 DBS centers (Berlin, Queensland, and Cologne). Based on individual electrode reconstructions, the volumes of tissue activated (VTAs) were estimated and combined with normative connectome data to identify structural connections passing through VTAs. Berlin and Queensland cohorts formed a training and cross‐validation dataset used to identify structural connectivity explaining change in depressive symptoms. The Cologne data served as the test‐set for which depressive symptom change was predicted.ResultsStructural connectivity was linked to depressive symptom change under STN‐DBS. An optimal connectivity map trained on the Berlin cohort could predict changes in depressive symptoms in Queensland patients and vice versa. Furthermore, the joint training‐set map predicted changes in depressive symptoms in the independent test‐set. Worsening of depressive symptoms was associated with left prefrontal connectivity.InterpretationFibers connecting the electrode with left prefrontal areas were associated with worsening of depressive symptoms. Our results suggest that for the left STN‐DBS lead, placement impacting fibers to left prefrontal areas should be avoided to maximize improvement of depressive symptoms. ANN NEUROL 2020;87:962–975
Nanogel Multienzyme Mimics Synthesized by Biocatalytic ATRP and Metal Coordination for Bioresponsive Fluorescence Imaging
Authors: Qi Meiyuan , Pan Hui , Shen Hongdou , Xia Xianmeng , Wu Chu , Han Xiaoke , He Xingyue , Tong Wei , Wang Xia , Wang Qigang 
Published: April 2020

AbstractThe design of enzyme mimics from stable and nonprotein systems is especially attractive for applications in highly specific cancer diagnosis and treatment, and it has become an emerging field in recent years. Herein, metal crosslinked polymeric nanogels (MPGs) were prepared using FeII ion coordinated biocompatible acryloyl‐lysine polymer brushes obtained from an enzyme‐catalyzed atomic transfer radical polymerization (ATRPase) method. The monoatomic and highly dispersed Fe ions in the MPGs serve as efficient crosslinkers of the gel network, and also as active centers of multienzyme mimics of superoxide dismutase (SOD) and peroxidase (POD). The catalytic activities were compared to those of conventional Fe‐based nanozymes. Studies on both cells and animals verify that efficient reactive oxygen species (ROS) responsive biofluorescence imaging can be successfully realized using the MPGs.