bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of methotrexate, vincristine, L-asparaginase and dexamethasone for salvaging adult acute lymphoblastic leukemia and lymphoma: a real-life experience
Authors: Tanrikulu Funda Pepedil , Buyukkurt Nurhilal , Yeral Mahmut , Aytan Pelin , Solmaz Soner , Korur Asli , Gereklioglu Cigdem , Kozanoglu İlknur , Boga Can , Ozdogu Hakan 
Published: October 2019

Despite recent improvements in the treatment options, adult relapsed/refractory Acute Lymphoblastic Leukaemia (ALL) and lymphoblastic lymphoma (LBL) exhibit poorer cure rates than in childhood. Since, the mainstay difference of childhood multidrug regimens is L-Asparaginase, we sought to salvage adult patients with a protocol containing methotrexate, vincristine, conventional L-asparaginase, and dexamethasone (MOAD). In this study, we aimed to summarize our experience.
Methods: Adult patients with relapsed/refractory ALL and LBL followed-up in our institution between 2017 and 2018 were reviewed and those treated with MOAD protocol were retrospectively included in the study. Clinical data, treatment responses, and adverse events were summarised. The protocol featured 28-day cycles of methotrexate 200 mg/m2 intravenously (IV) on days 1 and 15; vincristine 1.4 mg/m2 IV on days 1, 8, and 15; L-asparaginase 10,000 IU/m2 IV twice weekly; and dexamethasone 40 mg IV or orally on days 1–4 and 15–18.
Results: A total of eight patients were enrolled, of median age 37 years (range: 21–58 years). Four patients were recovered after transplantation. Complete remission was evident in 38%. Two such patients underwent allogeneic hematopoietic stem cell transplantation after the protocol. Another patient with lymphomatous disease achieved partial remission and underwent successful transplantation. L-asparaginase did not trigger any clinically evident hypersensitivity reaction; the most common adverse events associated with the protocol were hypofibrinogenemia, anemia, and febrile neutropenia.
Conclusions: The MOAD protocol was effective and tolerable, enabling to salvage before and after transplantation, particularly in patients with relapsed/refractory T-cell acute lymphoblastic leukemia and lymphoblastic lymphoma.
New and known species of the genus Campylaimus Cobb, 1920 (Nematoda: Araeolaimida: Diplopeltidae) from North European marine habitats
Authors: Holovachov Oleksandr 
Published: October 2019

The genus Campylaimus is a broadly distributed but relatively uncommon genus of marine and brackish nematodes with 20 nominal species and one nomen nudum. Many species descriptions and redescriptions are based on very few (single) individuals, which limits our understanding of inter- and intra-specific variability and morphology-based species boundaries.
Two new species were found in the Skagerrak off the west coast of Sweden. Campylaimus triclados sp. n. is characterised by body 0.59–0.69 mm long; cuticle without longitudinal striation; anteriormost edge of the amphid anterior to the oral opening; dorsal limb of the amphid equal to 1.6–2.5 labial region diameters in male, 1.9 labial region diameters in female; ventral limb of the amphid extends towards anterior part of the intestine in male and midpharynx in female, 4.3–5.5 times the length of the dorsal limb in male and 2.2–2.8 times the length of the dorsal limb in female; ventral limb of the amphid is as wide as the dorsal limb; interamphideal space extends further than the posterior end of the dorsal limb but not reaching the posterior end of the ventral limb; secretory-excretory pore opens posterior to the cardia; spicules 19–24 µm long; two precloacal supplements; tail equal to 4.3–5.6 anal body diameters in length, with conoid terminal part. Campylaimus longispiculus sp. n. is characterised by body 0.56–0.65 mm long; cuticle without longitudinal striation; anteriormost edge of the amphid anterior to the oral opening; dorsal limb of the amphid equal to 1.8–2.1 labial region diameters in male; ventral limb of the amphid extends towards anterior part of the intestine in male, 2.8–3.5 times the length of the dorsal limb in male; ventral limb of the amphid is as wide as the dorsal limb; interamphideal space absent; secretory-excretory pore opens posterior to the cardia; spicules 28–35 µm long; two precloacal supplements; tail equal to 4.9–5.3 anal body diameters in length, with clavate terminal part. In addition, following nine species are new records for the fauna of Sweden: Campylaimus amphidialis, C. inaequalis, C. lefeverei, C. minutus, C. orientalis, C. rimatus, C. siwaschensis, C. striatus and C. tkatchevi.
Limitations of stabilizing effects of fundamentalists: facing positive feedback traders
Authors: Baumann Michael Heinrich , Baumann Michaela , Erler Alexander 
Published: October 2019

Abstract
The authors analyze financial interactions between chartists with bounded leverage and fundamentalists within a heterogeneous agent model, focusing on the role of fundamentalists to stabilize prices. While many related studies are solely based on simulations, the authors analytically prove that the existence of fundamentalists is insufficient to avoid asset price bubbles for a certain setup of a feedback trader model. Moreover, similar studies very often face the criticism that chartists might run out of money before the emergence of bubbles, as these studies typically analyze the role of chartists with unbounded leverage. In the work at hand, however, the authors prove that even in an environment where chartists have limited access to finance, their investment behavior can lead to exploding prices. The chartists under study are so-called positive feedback traders, whose leverage is bounded. Additionally, the authors derive upper boundaries for positive feedback traders’ initial investment necessary to avoid exploding prices. In order to stabilize stock/asset markets, intervention measures might be helpful.
Semi-quantitative understanding of source contribution to nitrous acid (HONO) based on 1 year of continuous observation at the SORPES station in eastern China
Authors: Liu Yuliang , Nie Wei , Xu Zheng , Wang Tianyi , Wang Ruoxian , Li Yuanyuan , Wang Lei , Chi Xuguang , Ding Aijun 
Published: October 2019

Abstract. Nitrous acid (HONO), an important precursor of the hydroxyl radical (OH),
has long been recognized as of significance to atmospheric
chemistry, but its sources are still debated. In this study, we conducted
continuous measurement of HONO from November 2017 to November 2018 at the
SORPES station in Nanjing of eastern China. The yearly average mixing ratio
of observed HONO was 0.69±0.58 ppb, showing a larger contribution to
OH relative to ozone with a mean OH production rate of 1.16 ppb h−1. To
estimate the effect of combustion emissions of HONO, the emitted ratios of
HONO to NOx were derived from 55 fresh plumes (NO∕NOx > 0.85), with a mean value of 0.79 %. During the nighttime, the chemistry of
HONO was found to depend on RH, and heterogeneous reaction of NO2 on
an aerosol surface was presumably responsible for HONO production. The average
nighttime NO2-to-HONO conversion frequency (CHONO) was determined
to be 0.0055±0.0032 h−1 from 137 HONO formation cases. The
missing source of HONO around noontime seemed to be photo-induced, with an
average Punknown of 1.04 ppb h−1, based on a semi-quantitative
HONO budget analysis. An over-determined system of equations was applied to
obtain the monthly variations in nocturnal HONO sources. Besides the
burning-emitted HONO (accounting for about 23 % of the total concentration), the
contribution of HONO formed heterogeneously on ground surfaces to measured HONO was an
approximately constant proportion of 36 % throughout the year. The soil
emission revealed clear seasonal variation and contributed up to 40 % of
observed HONO in July and August. A higher propensity for generating HONO on
aerosol surfaces occurred in severe hazes (accounting for 40 % of the total concentration in
January). Our results highlight ever-changing contributions of HONO sources
and encourage more long-term observations to evaluate the contributions from
varied sources.
Implementing Response to Intervention (RtI) and Early Reading: A Review of Literature
Authors: Rios-Sobrevilla San Juanita , Huber Tonya 
Published: October 2019

Background: Response to Intervention (RtI) in early reading is known as the detailed process that is implemented to enhance the areas of reading in young children.Aims: The reviewers compare various approaches to Response to Intervention (RtI) and identify which frameworks are reported as most effective for young early readers.Method: The topic of Response to Intervention (RtI) in early reading was studied through a comprehensive review of the literature.Findings: Research results all show the overall improvement of student performance in reading as well as overall teacher growth in knowledge, delivery of instruction, confidence, and self-efficacy. Conclusion: Response to Intervention (RtI) in early reading has proven to be a successful and effective approach deserving the necessary attention by school staff and administration to be properly aligned and appropriately implemented.
“A Black School Is Not Supposed to Win”: Black Teamwork at Howard University, 1970–74
Authors: Scott Jermaine 
Published: October 2019

Abstract
The Americanization of soccer during the 1960s and 1970s marketed the game as a sport for white Americans. This process, however, was interrupted when Howard University’s soccer team, made up of black athletes from the Caribbean and Africa, won the national championship in 1971. The following year, the National Collegiate Athletic Association (NCAA) stripped Howard of its title because of apparent eligibility violations. This paper analyzes the racial governance of the NCAA and the ways in which Howard University responded to the Americanization of soccer—what I am calling “black teamwork.” Moreover, I am interested in the diasporic formation of Howard’s “black team” and the political implications it carries for black subjects seeking racial justice. In short, this essay will look at soccer as a space for the articulation of a diasporic black politics.
Methods of Studying the Semantic Function of Trademarks in the Industrial, Commercial and Advertising
Authors: N.A Stadulskaya , L.A Antipova 
Published: October 2019

Of the aim of this investigation is to show the methods of studying the trademarks development to better understand their role in modern economy and advertising. Along with the methods, we have tried to postulate that the concept “property” accelerate their wide-spreading and necessity. It was established that the creators (brand designers) use some cognitive techniques to make a new trade-name. Often some semantic methods help them to from a new name and in the article we tried to illuminate this linguistic aspect. Taking into consideration that all of our research is made into the semiotics field of science, we, of course, drew attention to the pragmatic aspect of the investigated linguistic material. We concluded that, all trademarks in certain teaching methods, effort at the implementation of the commercial intentions. The present article deals with the educational approaches aimed at the development of a positive evaluation in the perception of this or that trademark; phonosemantic strategies, implemented in the process of brand naming, are shown. According to the results we are going to continue our investigation in the field of semiotics, in other words we want to study verbal, non-verbal and heterogenous brands and mechanism and models of the methods.
Comparative Studies of Educating Methods of Different - Structured Languages: Etymological and Semantic Aspect
Authors: Shakirova Dilyara Sh. 
Published: October 2019

The concepts in English and Russian dictionary sources of various types are used in the study to help teachers. The aim is to investigate the educating methods, not only for foreign students but also native speakers of the Russian language to acquaint themselves with the ideas of interpretation of individual images by the representatives of a given nation In the course of the research, analyzing approximately 40 common methods of teaching (explanatory, encyclopedic, scientific and technical, etc.). Results confer the possibility of grasping the intended concepts of folklore, literary texts or folk art and as well as abstract concepts . However, these concepts emerge from the interaction of national tradition and folklore, religion and ideology, life experience and images of art, sensations and value systems of this ethnic system.
On Some Difficulties in Students’ Independent Work in Learning Foreign Languages
Authors: Ilyasova Asiya Mirgasimovna , Khakimzianova Alsu Saetzianovna , Fakhrutdinov Bulat Ildarovich 
Published: October 2019

The study conducted a questionnaire survey of university students, the purpose of which was to determine how students do their independent work while learning a foreign language and to reveal the difficulties in this process .The whole learning process of a structured in such a way as to arouse students' interest in those materials on the language that carry important and new information, in order to constantly maintain the desire to learn the language at home, so that students can see this need. Only in this case the study can have a positive effect on the development of such student qualities, purposefulness, organization, and perseverance. A brief analysis of students' answers about difficulties in independent work while learning foreign languages, the investigation emphasize that for the organization of the foreign language learning process, it is important to investigate not only the issues of the teacher’s work, questions of teaching methods, but also questions of organizing student’s work, namely, questions of studying and mastering skills in foreign languages.
Myofascial Release for Vulvar Pain and Pubic Shear After a Straddle Injury in a 3-Year-Old Girl
Authors: Dade Maggie M. , Broecker Jane D. 
Published: October 2019

Abstract
Pelvic malalignment is a somatic dysfunction that can lead to pelvic discomfort, despite normal genital examination findings. A 3-year-old girl presented with vulvar discomfort after a straddle injury sustained while riding a tricycle. The symptoms persisted despite standard medical treatment for vulvovaginitis and chronic vulvar irritation. An osteopathic structural examination revealed distortions of the bony pelvis, often associated with genitourinary complaints. After 5 osteopathic manipulative treatment sessions, the patient experienced significant relief. With persistent vulvar pain, somatic dysfunction should be considered in the differential diagnosis. A brief musculoskeletal examination of the pubic tubercles, iliac crest, and iliac spines can help to identify somatic dysfunction in a gynecologic patient with symptoms that are unresponsive to standard treatments.
Effects of Weather Conditions on Satellite Television Cable Network Reception Quality in Warri Metropolis, Delta State, Nigeria
Authors: Chukwuyem Graham Imarhiagbe, , Vincent Nduka Ojeh, 
Published: October 2019

The study examined the effects of weather conditions on satellite television cable network reception quality. The ex-post facto research design was used. The primary data were generated through personal observation/monitoring of Television sets that were connected to the three prominent networks (MYTV, DSTV, and HITV) in Warri. Rainfall stations were established in each of the sample areas and were used to collect rainfall amount between the months of May and August, being rainy season in the location. Additionally, wind speed, humidity, temperature and rainfall data were collected from the archives of the Nigerian Meteorological Agencies office in Warri for 20 years. A total of fifteen (15) TV sets and fifteen modems of MYTV, DSTV and HITV satellite-cable network were utilized for this study. Results showed that there is variation in the trends of climate parameters in Warri. There is variability in the rainfall, relative humidity as well as the wind speed trends in Warri from 1991-2011. The variations in these climate attributes have effects on the durability and functionalities of satellite cable network in the area. The reception quality for MYTV reduced from 69.8% on days without rainfall to 15.4% on rainy days during the study period, while DSTV signal quality reception was also reduced by rainfall and weather effect to 20.4% on rainy days from 85.6% mean on days without rainfall. HITV signal quality reception of 33.4% on days without rainfall was reduced to 7.2% by the effect of rainfall. Rainfall impairs signal quality. Further, the result revealed that there is a significant variation in cable network reception qualities of MYTV, DSTV and HITV. This is evident from the calculated F-value of 1028.136 which was greater than the critical table-value of 19.49 at 0.05 significant level. The r value shows a correlation of 0.989 between rainfall and MYTV reception quality. However, the R² value of 0.977 shows that 97.7% variation in the quality of signal reception from MYTV is explained by other weather parameters. The r value shows a correlation of 0.994 between wind speed and DSTV reception quality. However, the R² value of 0.988 shows that the quality of the signal reception from DSTV is explained by 98.8% dependency on weather parameters. Similarly, the r value shows a correlation of 0.970 rainfall and HITV reception quality. However, the R² value of 0.942 shows that the quality of the signal reception from MYTV is explained by 94.2% dependency on weather parameters. The policy implications of the findings of this study are that adequate and well-implemented weather monitoring with remote sensing/satellite-based platforms should be captured in the national laws of Nigeria.
Spatio-Temporal Pattern of Motorcycle Accidents in Anambra State, Nigeria
Authors: Umeh Peter P. , Ojeh Vincent N. , Arisabor Lucky , Ikporukpo Christopher O. 
Published: October 2019

This research work focuses on spatio-temporal pattern of motorcycle accidents in Anambra state, Nigeria. The study used mostly secondary data, accident records which were obtained from Federal Road Safety Commission Awka, Anambra state (RS 5.30). The data on motorcycle accidents were obtained for a period of ten (10) years (2007-2016). Analysis of variance (ANOVA) technique was employed in the examination of the statistical significance of the variation among the local government areas of the state. The result indicates that there is a significant variation in the number of motorcycle accidents among the local government areas of the state (F29, 189 = 2.609; p<0.05). Again analysis of variance was employed in the examination of the statistical significance of the variation of motorcycle accidents over time (2007-2016) in Anambra state. The result indicates that there is a significant difference in the number of motorcycle accidents from 2007-2016 (F9, 200= 13.210; p<0.05). Multiple regression analysis was employed in the examination of some of the characteristics of the local government areas of the state. It was observed that, there is a joint prediction of motorcycle accidents by a combination of some of the characteristics of the LGA of the state (p<0.05), the result implies that other characteristics of the Local Government areas of the state played little influence on the number of motorcycle accidents that occurred in 2011. The need for re-orientation of the land use pattern in the study area, better road network characteristics, Government should set up more police patrols for the highways in order to enforce road traffic regulation including speed limits and the need to establish Federal Road Safety Corps archive where accident records will be kept, collated and processed are desirable.
Chemical Characterization of Aeolian Dust Deposition in Southern and Western Iran
Authors: Foroushani Mansour A. , Opp Christian , Groll Michael 
Published: October 2019

In the last decade, the southwestern and western provinces of Iran have been heavily affected by aeolian dust deposition. As a result, the elemental composition of soil surfaces is influenced by dust transport as well as precipitation, wind speed and direction. The relationship between daily recorded dust events and the elemental composition of the dust is studied in this paper. Strong correlations were detected between dust deposition rate from most deposition sites (G01-G10, except for G05, G06) and the dust event frequency. Correlations of different strengths have been revealed between the dust event frequencies (DEF), and the elemental classification matrix based on airborne Metal Regulations.
As expected, high correlation values indicate high concentration contributions of elemental values to the aerosol, such as Na, Mn, As, Pb, from large-scale depositions in the south including Cr and V in the west. These findings also suggest that the major contributors of V, Cr, Co, Ni, Cu, Zn, As, Se, Cd, Ba, and Pb in the elemental concentrations may depend on the meteorological situation and correlation magnitude are associated with elements emanating from local anthropogenic activities.
Monitoring Coastline Changes in the Coastal Belt of Chittagong in Bangladesh Using GIS and Remote Sensing
Authors: Khan Md. Shakil , Das Jewel , Kabir Md. Humayain 
Published: October 2019

Coastal zones are the most dynamic feature of earth surface in which lithosphere, hydrosphere and atmosphere gets into contact with each other. Such dynamic process should be monitored with great importance as a large portion of the world’s population is living along the coastal zones. This paper focuses on delineation of the changes in the coastal land areas of Chittagong in Bangladesh through the shifting of coastline. Chittagong coastal area is around 245 km with an unbroken 125 km gently slopped sandy sea beach in Cox’s Bazar. However, due to both the natural phenomenon and human interventions, coastline in these areas has been changing gradually. These changes have occurred in relation to land biomass, erosion and accretion rate. Therefore, shoreline geometry analysis can help understand such dynamic coastal process. Several satellite images from Thematic Mapper (TM) and Enhanced Thematic Mapper (ETM) were used for the long term coastline change analysis. The digital shoreline analysis (DSA) using ArcGIS 10.1, and image rectification, atmospheric correction, edge separation techniques between earth surface and water surface using ENVI software were used in this analysis. DSAS was used as a reliable statistical approach for the rate of coastline change. The result shows that changes in dynamic changes due to erosion and accretion have been impacting the morph-dynamics in the study area. The maximum accession rate was 3.6 km and 1.9 km at different section points and on the contrary the maximum erosion at several section points was 0.37 km and 3.3 km at the time interval of 1989 to 2009 and 2009 to 2014, respectively. Overall, it was found that the area was affected with huge rate of accretion and increase in the landmass of the Chittagong area till the year 2009 but later on till the date of 2014 the erosion rate of the area again increased. The findings of this study can help policy makers to make decisions in delineating new islands emerging at the sea boundary of Bangladesh and planning for better coastal management.