bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of ozonated Aloe vera oil in full-thickness skin defects: Macrophage count and epithelization length parameter
Authors: Tamba Ukio Salferius , Arifin Muhamad Thohar , Nur Muhamad , Muniroh Muflihatul , Susilanigsih Neni 
Published: October 2020

Background: Aloe vera has been reported to enhance keratinocyte proliferation and migration, and thereby accelerate wound healing. Ozone therapy is an alternative medicine with disinfecting properties and strong oxidative stress induction capacity. This study aimed to evaluate the effect of Aloe vera oil provided with different dosages of ozone in accelerating the healing rate comparing two-phases; inflammation (day 3) and proliferation (day 7) of full-thickness defect wounds in Sprague Dawley rats as an adjuvant treatment based on macrophage count and new epithelialization length. Methods: We conducted a study using a post-test only control group design, where a total of 50 Sprague Dawley rats were randomized into ten groups. Two control groups were administered Aloe vera oil (P1, P6), while gentamicin ointment was used in the other control group (P2, P7). Ozonated Aloe vera oil dose was used: 600 mg/ml (P3,P8), 1200 mg/ml (P4,P9), and 1800 mg/ml (P5,P10). Groups P1, P2, P3, P4, P5 were terminated on the 3rd day, while P6, P7, P8, P9, P10 were evaluated on the 7th day. Macrophage counts were assessed using a 100x magnification microscope, through hematoxylin-eosin (HE) staining, and paraffin block with Masson trichrome staining was used to measure the new epithelialization length. Results: There were significant differences in the macrophage count on day three between the group-administered gentamicin (P2) and 1800 mg/ml ozonated Aloe vera oil (P5) (79.96;131.96, p<0,05). The new epithelialization length significantly increased in the group provided with wound treatment up to day 7, using 1800 mg/ml ozonated Aloe vera oil (P10), compared to non-ozonated Aloe vera (P6) and the gentamicin therapy (P7) (1160.88 µm; 1367.64; 2451.40 μm, p<0,05). Conclusions: The application of ozonated Aloe vera oil to full-thickness skin defects in Sprague Dawley rats resulted in a higher macrophage count and longer new epithelialization length than in controls.
Non-invasive somatotransgenic bioimaging in living animals
Authors: Delhove Juliette M. , Karda Rajvinder , FitzPatrick Lorna M. , Buckley Suzanne M.K. , Waddington Simon N. , McKay Tristan R. 
Published: October 2020

Bioluminescence imaging enables noninvasive quantification of luciferase reporter gene expression in transgenic tissues of living rodents. Luciferase transgene expression can be regulated by endogenous gene promoters after targeted knock-in of the reporter gene, usually within the first intron of the gene. Even using CRISPR/Cas9 mediated genome editing this can be a time consuming and costly process. The generation of germline transgenic (GLT) rodents by targeted genomic integration of a gene expression cassette in embryonic stem (ES) cells is commonplace but results in the wastage of large numbers of animals during colony generation, back-crossing and maintenance. Using a synthetic/truncated promoter-driven luciferase gene to study promoter activity in a given tissue or organ of a GLT also often results in unwanted background luciferase activity during whole-body bioluminescent imaging as every cell contains the reporter. We have developed somatotransgenic bioimaging; a method to generate tissue-restricted transcription factor activated luciferase reporter (TFAR) cassettes in rodents that substantially reduces the number of animals required for experimentation. Bespoke designed TFARs are delivered to newborn pups using viral vectors targeted to specific organs by tissue-tropic pseudotypes. Retention and proliferation of TFARs is facilitated by stem/progenitor cell transduction and immune tolerance to luciferase due to the naïve neonatal immune system. We have successfully applied both lentiviral and adeno-associated virus (AAV) vectors in longitudinal rodent studies, targeting TFARs to the liver and brain during normal development and in well-established disease models. Development of somatotransgenic animals has broad applicability to non-invasively determine mechanistic insights into homeostatic and disease states and assess toxicology and efficacy testing. Somatotransgenic bioimaging technology is superior to current whole-body, light-emitting transgenic models as it reduces the numbers of animals used by generating only the required number of animals. It is also a refinement over current technologies given the ability to use conscious, unrestrained animals.
Upcoming Christmas jump in LIBOR
Authors: Mikheev Vikenty , Miheev Serge E. 
Published: October 2020

Background: London Interbank Offered Rate (LIBOR) exists since 1986 as a benchmark interest rate. Methods: Using two-layer linear regression method, we found a pattern of shortterm nature in LIBOR behaviour. Results: To wit, 2-month LIBOR experiences a jump after Xmas for the last two decades. The direction and size of the jump depend on the data trend on 21 days before Xmas. Conclusions: The obtained results can be used to build a winning strategy on the Swap Market.
Use of social media in the marketing of agricultural products and farmers’ turnover in South-South Nigeria
Authors: Inegbedion Henry , Inegbedion Emmanuel , Asaleye Abiola , Obadiaru Eseosa , Asamu Festus 
Published: October 2020

Background: The study investigated the use of social media in the marketing of agricultural products and farmers turnover in South-South Nigeria. The purpose of the study was to determine the extent to which the usage of social media in the marketing of agricultural products in Nigeria can enhance efficiency and farmers’ sales turnover. Methods: It employed the survey research design and data were collected with the help of a structured questionnaire. Research data were analysed using t-test and least square method. Results: The results showed that the use of social media (Facebook, WhatsApp and Instagram) in the marketing of agricultural products enhances efficiency and turnover of farmers through a significant reduction in the cost of marketing agricultural products as well as increased awareness and the attendant increase in demand for agricultural produce. Conclusions: The use of social media (WhatsApp and Instagram) in the marketing of agricultural products significantly influences cost reduction and hence efficiency in marketing as well as enhances turnover of farmers through increased demand for agricultural products. Thus, the adoption of social media in the marketing of agricultural products enhances the efficiency of agricultural marketing and sales turnover of farmers in south-south of Nigeria but only the use of WhatsApp and Instagram predict efficiency and sales turnover of farmers.
Psychological and pedagogical characteristic of application of methods of promotion and punishment as means of socialization of teenagers with deviant behavior
Authors: Erofeeva Mariya , Zuykova Anna , Safronov Aleksey 
Published: October 2020

The article handels the problem of using the methods of encouragement and punishment as a means of socializing adolescents with deviant behavior. Faced with various difficulties, a teenager may experience difficulties in the process of assimilation and reproduction of social experience that make up the essence of socialization. Against the background of objective difficulties in the process of following social norms, this category of children is faced with a variable pedagogical impact.
The main objective of the study was to identify the existing differences in the perception of the effectiveness of the methods of promotion and punishment as means of socialization in adolescents (as objects of education) and teachers (as subjects of education).
Materials and research methods In order to identify among teachers, their preferred forms of encouragement or punishment when working with deviant adolescents, at the first stage of the study, we used an author's questionnaire for teachers, which included questions about the teaching experience most often used in working with deviant teenagers of forms of encouragement and punishment, on the effectiveness of using methods of encouragement and punishment with this category of children. In addition, within the framework of this questionnaire, teachers had the opportunity to express a subjective opinion on the advisability of including in the educational process the missing forms of encouragement and punishment. The research sample included 7 teachers, carried out by class teachers in grades 7–9 of educational institutions in Kolomna, Moscow Region.
Results of the study Our study allows us to conclude that in most cases the expectations of children associated with receiving the desired promotion are not met, which in turn can subsequently form a negative attitude of the teenager towards the teacher, as well as a decrease in motivation in the performance of a task.
In addition, we have identified significant differences between the applied teachers and preferred forms of punishment by children. So, for example, if educators consider the most effective form of punishment as public censure, then children, on the contrary, prefer loyal methods of punishment, talking about such forms as remarking and removal from fulfilling responsible assignments, arguing that public punishment degrades the dignity of the child and causes even greater aggression and a desire to do “everything against”.
An interesting fact is that the teachers are against such a form of punishment as “removal from the class”, although the students themselves are not at all against such a measure, explaining this by saying that if the child interferes with the lesson, then he must leave the class.
Animated Video for Increasing Primary School Teachers’ Knowledge Regarding First Aid Management of Dental Avulsion
Authors: Katthika Vassa Khema , Fauziah Eva , Budiardjo Sarworini Bagio 
Published: October 2020

Introduction: Dental avulsion is a condition in which the tooth is completely dislodged from its socket. Inappropriate management when trauma occurs can complicate the prognosis of the tooth. The majority of injuries to children's teeth occur in the school environment and teachers play an essential role in providing first aid at the accident site. However, the school teacher’s knowledge regarding first aid dental avulsion is inadequate. Objectives: The purpose of this study was to analyze the effect of an animated video (First Aid Management of Dental Avulsion) on the knowledge of primary school teachers. Materials and methods: This clinical experimental study comprised 54 teachers from 13 public elementary schools in Central Jakarta who were chosen randomly to fill out a questionnaire before and after watching the animated video. Results: Data analysis using the Wilcoxon comparative test showed that there was a statistically significant increase (P<.05) in knowledge after watching the animated video. Conclusion: Thus, the animated video was effective in increasing the knowledge regarding first aid management of dental avulsion among the primary school teachers. Keywords: audiovisual aid; first aid; school teachers; tooth avulsion
Nurse-Administered Propofol Continuous Infusion Sedation: A New Paradigm for Gastrointestinal Procedural Sedation
Authors: Lin Otto S. , La Selva Danielle , Kozarek Richard A. , Weigel Wade , Beecher Ryan , Gluck Michael , Chiorean Michael , Boden Elisa , Venu Nanda , Krishnamoorthi Rajesh , Larsen Michael , Ross Andrew 
Published: October 2020

INTRODUCTION:
Nurse-Administered Propofol Continuous Infusion Sedation (NAPCIS) is a new nonanesthesia propofol delivery method for gastrointestinal endoscopy. NAPCIS is adopted from the computer-assisted propofol sedation (CAPS) protocol. We evaluated the effectiveness, efficiency, and safety of NAPCIS in low-risk subjects.

METHODS:
Between December 2016 and July 2017, patients who underwent esophagogastroduodenoscopy or colonoscopy with NAPCIS at our center were compared against 2 historical control groups of similar patients who had undergone procedures with CAPS or midazolam and fentanyl (MF) sedation.

RESULTS:
The mean age of the NAPCIS cohort (N = 3,331) was 55.2 years (45.8% male) for 945 esophagogastroduodenoscopies and 57.8 years (48.7% male) for 2,386 colonoscopies. The procedural success rates with NAPCIS were high (99.1%–99.2%) and similar to those seen in 3,603 CAPS (98.8%–99.0%) and 3,809 MF (99.0%–99.3%) controls. NAPCIS recovery times were shorter than both CAPS and MF (24.8 vs 31.7 and 52.4 minutes, respectively; P < 0.001). On arrival at the recovery unit, 86.6% of NAPCIS subjects were recorded as “Awake” compared with 82.8% of CAPS and 40.8% of MF controls (P < 0.001). Validated clinician and patient satisfaction scores were generally higher for NAPCIS compared with CAPS and MF subjects. For NAPCIS, there were only 4 cases of oxygen desaturation requiring transient mask ventilation and no serious sedation-related complications. These low complication rates were similar to those seen with CAPS (8 cases of mask ventilation) and MF (3 cases).

DISCUSSION:
NAPCIS seems to be a safe, effective, and efficient means of providing moderate sedation for upper endoscopy and colonoscopy in low-risk patients.
PENGARUH KESELAMATAN DAN KESEHATAN KERJA TERHADAP PRESTASI KERJA KARYAWAN PADA PT. PLN (PERSERO) APJ SEMARANG
Authors: Paramitha Catarina Cori Pradnya , Wijayanto Andi 
Published: October 2020

The objective of this research is to find out the influence of Occupational Health and Safety Program toward the performance of the employees mediated by work motivation. The method of data collection in this explanatory research employs questionnaire, interview, observation, and documentation. From the population of 188 employees, the proportional stratified random sampling method results in 55 employees as the sample. Data analysis uses Path Analysis. Based on the result of the research, it can be concluded that Occupational Health and Safety Program has positive and significant influence mediated by the variable of work motivation. PT. PLN (Persero) APJ Semarang should improve its Occupational Health and Safety Program to increase employees’ work motivation which in turn will result in maximum work performance. Penelitian ini bertujuan untuk membuktikan pengaruh keselamatan dan kesehatan kerja (K3) terhadap prestasi kerja karyawan yang dimediasi variabel motivasi kerja. Teknik pengumpulan data menggunakan kuesioner, wawancara, observasi dan dokumentasi. Populasi dalam penelitian ini adalah seluruh karyawan PT. PLN (Persero) APJ Semarang yang berjumlah 118 orang. Metode pengambilan sampel menggunakan proportionate Stratified Random Sampling dan ditetapkan sampel sebanyak 55 orang. Analisis data dilakukan dengan menggunakan analisis jalur. Berdasarkan hasil penelitian, maka dapat disimpulkan bahwa keselamatan kerja dan kesejahteraan (K3) berpengaruh signifikan terhadap kinerja karyawan yang dimediasi oleh variabel motivasi kerja. PT. PLN (Persero) APJ Semarang seharusnya untuk meningkatkan K3 bagi karyawan agar motivasi kerja mereka menjadi lebih tinggi, sehingga mereka dapat memberikan performa yang maksimal.Keywords: Occupational Health and Safety, Work PerformanceKeselamatan dan Kesehatan Kerja, Prestasi Kerja
Limitation of Erlang B Traffic Model in Elastic Optical Network for Blocking Probability Estimation
Authors: Ujjwal  , Thangaraj Jaisingh 
Published: October 2020

Abstract
In this paper, an algorithm for multipath connection provisioning in elastic optical network (EON) has been proposed. Initially, the algorithm prefers the single-path routing for service provisioning. But when single-path routing is not adequate to serve a dynamic connection, the algorithm switches to the connection request fragmentation. Its computation is based on the parameters such as capacity_constant and capacity_allowed to fragment the connection request on disjoint paths. Simulation results clearly state that the proposed algorithm performs well in service provisioning as compared to the traditional single-path routing algorithms and improves the average network throughput. Thereafter, we have investigated the limitation of Erlang B traffic model in EON for calculation of link blocking probability using routing and spectrum assignment (RSA) algorithm. It is verified by the following two ways: (i) effect on the blocking probability in case of constant load and (ii) effect of slot width on the blocking probability. Our simulation results indicate that in EON due to dynamic RSA, blocking probability is not constant in case of proportionate varying of call arrival and service rate giving constant load and blocking probability depends on the number of slots per link, but in Erlang B traffic model blocking probability is always constant in case of constant load and it considers wavelength per link instead of slots per link. This is attributed to the fact that Erlang B traffic model fails to calculate blocking probability accurately in EON. We have computed the carried traffic on 14 nodes, 21-link National Science Foundation Network (NSFNET) topology.
40 Gbps Laguerre-Gaussian and Hermite-Gaussian Optical Mode Division Multiplexing for Radio over Fiber System
Authors: Mahmood Hussein Ahmed 
Published: October 2020

Abstract
Radio over Fiber technology is utilizing the high capacity of optical fiber system and wireless mobility network. In this work, we proposed two different optical propagation modes namely Laguerre-Gaussian (LG) and Hermite-Gaussian (HG) setting to (0.1), (0.2) mode types generated by a special CW laser source at varying wavelength from 800 nm to 1150 nm with 50 nm spacing channel Mode division Multiplexing (MDM) technique. These wavelengths transmitted×5Gb/s data modulated on PSK modulator having 100 GHz radio frequency subcarrier over 5 km Parabolic-Index Multimode Fiber link. Q factor value and eye diagram used to evaluate system performance which showed the maximum Q factor value found at 800 nm channel 1 equal to 12.0113 for both LG 0 1 and HG 0.1. While the maximum Q factor appears at 800 nm channel 1 equal to 8.49756 for LG 0,2 and 3.56785 at 1000 nm channel 5 for HG 0.2.
Effects of Curcumin and Fenugreek Soluble Fiber on the Physical Working Capacity at the Fatigue Threshold, Peak Oxygen Consumption, and Time to Exhaustion
Authors: Herrick Lauren P. , Goh Jensen , Menke Walter , Campbell Marilyn S. , Fleenor Bradley S. , Abel Mark G. , Bergstrom Haley C. 
Published: October 2020

Abstract
Herrick, LP, Goh, J, Menke, W, Campbell, MS, Fleenor, BS, Abel, MG, and Bergstrom, HC. Effects of curcumin and fenugreek soluble fiber on the physical working capacity at the fatigue threshold, peak oxygen consumption, and time to exhaustion. J Strength Cond Res 34(12): 3346–3355, 2020—The purpose of this study was to examine the effects of curcumin in combination with fenugreek soluble fiber (CUR + FEN) or fenugreek soluble fiber alone (FEN) on the neuromuscular fatigue threshold (PWCFT), peak oxygen consumption (V˙o2peak), and time to exhaustion (Tlim) on a graded exercise test (GXT), in untrained subjects. The PWCFT estimates the highest power output that can be maintained without evidence of neuromuscular fatigue. Forty-seven untrained, college-aged subjects were randomly assigned to one of 3 supplementation groups; placebo (PLA, n = 15), CUR + FEN (500 mg·d−1, n = 18), or FEN (300 mg·d−1, n = 14). The subjects completed a maximal GXT on a cycle ergometer to determine the PWCFT, V˙o2peak, and Tlim before (PRE) and after (POST) 28 days of daily supplementation. Surface electromyographic signals were recorded from a bipolar electrode arrangement on the vastus lateralis of the right leg during each test. Separate one-way analysis of covariances were used to determine if there were between-group differences for adjusted POST-PWCFT, POST-V˙o2peak, and POST-Tlim values, covaried for the respective PRE-test scores. The adjusted POST-PWCFT for the CUR + FEN group (mean ± SD: 196 ± 58 W) was greater (p = 0.016) than the PLA group (168 ± 49 W) but the FEN group (185 ± 32 W) was not different from the CUR + FEN or PLA groups (p > 0.05). There were no differences for adjusted POST-V˙o2peak (p = 0.612) or POST-Tlim (p = 0.508) among the groups. These findings suggested curcumin combined with fenugreek soluble fiber might delay neuromuscular fatigue.
Postactivation Potentiation Effect of Heavy Sled Towing on Subsequent Sprints
Authors: Williams Jason J. , Herron Robert L. , Spradley Brandon , Saracino Patrick 
Published: October 2020

Abstract
Williams, JJ, Herron, RL, Spradley, B, and Saracino, P. Postactivation potentiation effect of heavy sled towing on subsequent sprints. J Strength Cond Res 35(5): 1229–1233, 2021—Recent research supports heavy sled towing as a tool used to improve subsequent sprints as part of postactivation potentiation (PAP) protocols. The purpose of this study was to examine the effect of heavy sled towing using a velocity decrement (Vdec) on subsequent unloaded sprinting in high school football (soccer) athletes sprinting on artificial turf. A sled load equating to a 40–50% Vdec range was used (66–70% body mass). Fifteen (n = 9 boys and n = 6 girls) high school football players volunteered for this study. The sled-towing intervention consisted of a dynamic warm-up, 3 submaximal sprint efforts (50, 75, and 95%), and 3 maximum speed 15-m sled sprints, separated by 2-minute rests, of which the fastest time was recorded for analysis. Peak preintervention 15-m baseline sprint times were compared with peak post sled-towing 15-m sprint times using a paired samples t-test. Thirteen of 15 athletes ran faster peak post sled-towing sprint times than peak preintervention baseline sprint times (9 boys and 4 girls). On average, peak post sled-towing sprint times (2.60 ± 0.10 seconds) were 0.10 seconds faster (p < 0.0001; Cohen's d = 0.92) than peak preintervention baseline sprint times (2.70 ± 0.09 seconds). This research established that sled-towing protocols using loads corresponding to Vdec of 40–50% significantly improved subsequent sprints in high school football (soccer) athletes running on artificial turf.
Evaluation of a Reactive Agility Assessment Device in Youth Football Players
Authors: Hoffman Jay R. 
Published: October 2020

Abstract
Hoffman, JR. Evaluation of a reactive agility assessment device in youth football players. J Strength Cond Res 34(12): 3311–3315, 2020—The purpose of this study was to examine the reliability and validity of the Blazepod reactive agility device on sport-specific movements in competitive youth football players. Thirty-one male athletes (16.7 ± 1.5 years; 179.4 ± 7.0 cm; 75.0 ± 21.0 kg), all members of a youth tackle football team, volunteered to participate in this study. Subjects performed 3 reactive agility drills (side shuffle reactive agility, 1-m reactive agility, and 3-m reactive agility) at least 72 hours apart. In addition, all subjects also performed 3 traditional agility exercises: proagility, T drill, and L drill. These sessions were part of the offseason conditioning program for the football team that involved sport-specific drills. All assessments occurred following a warm-up and conducted in the same order on each occasion. To assess the validity of the reactive agility drills, the head coach was asked to rank the football playing and agility ability of the players participating in the study. The intraclass correlation coefficient values indicated that all 3 reactive agility drills displayed excellent reliability (r's ranging from 0.833 to 0.884). The measurement error was smaller than the individual variability, indicating that measurement error had a very limited effect on the results. Subjective rankings for agility significantly correlated with each of the agility and reactive agility measurements. Results of this study indicate that the Blazepod reactive agility device is a reliable measure of reactive agility performance and are consistent with the coach's perception of the athlete's agility performance, thus demonstrating construct validity.