bluuebunny/crossref_metadata_2025_split huggingface dataset:
Espectro de lesiones en imágenes de tomografía computarizada y resonancia magnética, en deportistas que participaron en los Juegos Olímpicos de la Juventud Buenos Aires 2018. Nuestra experiencia (Spectrum of lesions in Computed Tomography and Magnetic Resonance Imaging in young athletes that participated in the Olympic Youth Games. Buenos Aires 2018)
Authors: Sartori Pablo Martín , Viña Agustín , Arcos Andrés , Roberts Fernando , Barasatián Patricia , Yampolski Braian 
Published: November 2019

Objetivo: Describir las lesiones evaluadas por imágenes de los atletas que participaron en los Juegos Olímpicos de la Juventud Buenos Aires 2018.Materiales y Métodos: Se llevó a cabo un estudio descriptivo con una serie de 39 deportistas que participaron en los Juegos Olímpicos de la Juventud Buenos Aires 2018 y se sometieron a estudios por imágenes. Se analizaron los siguientes datos: distribución por sexo, edad, país, disciplina deportiva y hallazgos patológicos.Resultados: Se atendió a más deportistas mujeres (61,53%), la mayoría (33,33%) era de América del Sur. El atletismo fue la disciplina que más pacientes aportó(7 estudios). Predominaron las lesiones de los tejidos blandos de los miembros inferiores (79,41%).Conclusiones:Las atletas fueron quienes más se realizaron estudios de imágenes, y las lesiones más frecuentes fueron las de los tejidos blandos de los miembros inferiores. AbstractObjective: To describe the sports injuries in young athletes that participated in the Olympic Youth Games. Buenos Aires 2018.Materials and methodology: A descriptive study with 39 sportsmen, that realized imaging studies, that participated in Youth Olympic Games Buenos Aires 2018. Athlete’s distribution by sex, age, sports discipline, and pathologic findings was analyzed.Results: 4012 athletes participated in Youth Olympic Games Buenos Aires 2018, with the particularity that the number of woman and male are equal. The most frequent lesions were in female athletes (61, 53 %), the high proportion were in South America (33, 33 %). Athletics was the discipline that more patients reported (7 studies). Soft tissues injuries were predominant in sportswomen, especially in the lower limb (79, 41 %).Conclusion: Young woman were made more imaging studies, most frequent lesions were in the soft tissues of the lower limbs.
Is gonadotropin-releasing hormone agonist usage really leading to thyroid dysfunction?
Authors: Yilmaz Nafiye , Hancerliogullari Necati , Kara Mustafa , Engin-Ustun Yaprak 
Published: November 2019

Objectives Gonadotropin-releasing hormone agonist (GnRHa) could influence the levels of sex hormones and thyroid hormones. The aim of this study was to investigate the effect of GnRHa on thyroid function. Materials and methods The data of the patients were collected from the registrations of July 2014–October 2014. A total of 41 women who underwent one-time IVF cyclus were evaluated in this cross-sectional study. The patients were categorized into two groups according to the serum T3, T4, and TSH levels before and 2 weeks’ after the administration of GnRHa. Results Mean basal TSH and mean TSH levels on hCG day were 1.98 ± 0.77 and 1.75 ± 0.70, respectively. The difference between the two groups was statistically significant (p < 0.05). GnRHa did not lead to statistically significant difference on serum-free T3 and T4 levels. Conclusions In conclusion, our results demonstrate that GnRHa led to a decrease on serum TSH level. Serum-free T3 and T4 levels were remained unchanged and this might be due to early measurement of the hormone levels (just 2 weeks later from GnRHa administration).
Features of surgical treatment of intra- and periarticular fractures of the lower third of the femur in patients with polytrauma
Authors: Solod E. I. , Zagorodni N. V. , Lazarev A. F. , Abdulkhabirov M. A. , Alsmadi Ya. M. , Dmitrov I. A. 
Published: November 2019

Treatment of patients with fractures of femur has a particular relevance in modern traumatology, especially in patients with polytrauma. The treatment of such fractures is complicated by the fact that it depends not only on the nature of the fracture, but also on the general condition of the patient. These fractures are caused by high- energy trauma, they have the tendency to be splintered or fragmented, and often accompanied by neurovascular complications, especially in the distal part. Such fractures are often accompanied by soft tissue damage. Purpose: improving the results of treatment of intra-and periarticular fractures of the distal femur in patients with polytrauma.
Material and methods. In the present study, a prospective analysis of using conversion osteosynthesis in the treatment of 72 patients with intra-and periarticular fractures of the lower third of the femur patients with polytrauma, according to the ISS severity scale (ISS 1740) was performed in a multidisciplinary hospital.
Results. The most optimal time for conversion osteosynthesis to patients with polytrauma was 5 7 days, which prevented the occurrence of traumatic shock and prevented the occurrence of inflammatory complications in the postoperative period.
Conclusion. The study confirmed the feasibility of conversion osteosynthesis in the treatment of patients with intra-and periarticular fractures of the lower third of the femur. The use of the technique of transferring the fixation of fragments by the external fixation to the internal osteosynthesis (conversion) contributed to a reduction in the duration of treatment of patients in the hospital with fractures of the long bones.
Смертность от дорожно-транспортных происшествий в России: подходы к оценке, тенденции и перспективы
Authors: Пьянкова Анастасия Ивановна , Фаттахов Тимур Асфанович 
Published: November 2019

В России в 2016 г. общий коэффициент смертности от ДТП по данным полиции впервые снизился до уровня, не наблюдавшегося с 1971 г., после чего продолжил снижаться. Позитивные тенденции, видимо, послужили основой для оптимистичных целей, заложенных в стратегии безопасности дорожного движения на 2018-2024 гг. (стратегия БДД).
Опираясь на данные полиции, государственную статистику смертности, международные базы данных о смертности и безопасности дорожного движения, авторы пытаются ответить на вопросы: достижимы ли поставленные цели в указанные сроки, насколько они согласуются с европейскими тенденциями дорожно-транспортной смертности, а также с существующей в России пространственной, возрастной и категориальной дифференциацией дорожно-транспортной смертности.
Исследование показало, что установленные сроки достижения целевых ориентиров в стратегии БДД очень сжаты. На сегодняшний день лишь в крупных и средних по численности населения городах есть потенциал для реализации стратегии, где общий коэффициент смертности к 2024 г. не должен превышать 1,5-2 погибших на 100 тыс. человек, тогда как в небольших городах и сельских населенных пунктах – 2,5-3 погибших на 100 тыс. человек. На протяжении долгих лет наибольшему риску смерти на российских дорогах подвержены водители и пассажиры в возрасте 15-44 года и пешеходы старше 60 лет, не нашедшие отражения в стратегии БДД в качестве приоритетных категорий.
Помимо этого, в статье показано, что для устранения существующих расхождений между опубликованными числами погибших двух официальных систем учета (полиции и Росстата) самым первым шагом может быть отказ Росстата от используемого в данный момент подхода к выделению контингента погибших в ДТП на основе действующей краткой номенклатуры причин смерти и переход на один из двух международных вариантов агрегации трехзначных кодов причин смерти, используемый ВОЗ для выделения числа погибших в ДТП.
Diagnostic yield of cartridge based nucleic acid amplification test in Mycobacterium tuberculosis in a tertiary care medical college and hospital of Southern Odisha, India
Authors: Manoranjan Dash , Samal Satyajit , Rekha Swain Trupti , Bibhuprasad Behera , Swapnasarit Sahu , Sweekruti Mahapatra 
Published: November 2019

Background: Tuberculosis is the ninth leading cause of death worldwide. India contributes to about one fifth of global TB burden. It is very important to diagnose early and treat tuberculosis to cut down transmission of tuberculosis.Methods: Author conducted a retrospective study in Department of Pulmonary Medicine SLN Medical College, Koraput, Odisha to analyze the utility and yield of CBNAAT. Study period was from April 2018 to March 2019. Inclusion criteria was all patients whose samples were subjected to CBNAAT were included in our study. Sputum samples from pulmonary tuberculosis patients, and extra pulmonary samples (pleural fluid, ascitic fluid, CSF, synovial fluid and gastric lavage etc. were included in our study population. Exclusion criteria was patients who were under anti tubercular therapy for pulmonary, extra pulmonary and MDR TB were excluded from this study. Data were collected from Pulmonary Medicine Department, ART center, DOTS center and CBNAAT center. Total number of samples tested for CBNAAT, different sample collection sites, age and sex distribution of patients, HIV status of all patients, result of smear microscopy for AFB and CBNAAT and Rifampicin resistance status were analyzed.The detail statistical analysis was done in tabulation form.Results: A total of 2621 samples were tested in CBNAAT during the study period. Mean age of the study population was 38.03 years. 1881 tested were negative and 740 samples were positive for CBNAAT. Of these 2621 samples, 2526 were pulmonary samples (sputum, pleural fluid samples) and 95 were extra pulmonary samples. Author found rifampicin resistance rate of 0.54% (4/740)) in pulmonary tuberculosis cases. There was no rifampicin resistance detected in extra pulmonary samples. CBNAAT could identify 536 cases (23.2%) that were smear negative. Author found TB- HIV co-infection rate of 6.22%.Conclusions: CBNAAT is an important diagnostic modality especially in sputum negative patients for early diagnosis and treatment. In our study it detected Mycobacterium tuberculosis in 23.2% of patients with negative smear for microscopy. Rifampicin resistance rate detected was very low compared to other studies.
La educación secundaria y superior en Colombia vista desde las pruebas Saber.
Authors: Castro Mayerlin , Ruíz Jorge Vicente 
Published: November 2019

Las pruebas estándar generan debate al evaluar la calidad de la educación. Empero, son una herramienta de caracterización de los estudiantes. Colombia parece ser el único país del mundo en que se puede hacer el seguimiento de la prueba estándar de secundaria y universitaria para el mismo estudiante. El estudio busca caracterizar a los estudiantes que presentaron ambas pruebas. Se llevan a cabo tablas de contingencia en EXCEL para los estudiantes en Colombia que lograron terminar su bachillerato y pregrado, y presentaron la prueba Saber 11 en 2005-2006 y 4-5 años después Saber Pro en instituciones tanto técnicas como universitarias (N=25,980), y solo universitarias (N=18,845). Seis de cada diez estudiantes que terminaron sus estudios superiores asistieron a un colegio o a una universidad del sector privado. Aproximadamente dos de cada tres estudiantes que terminan sus estudios superiores lo hacen en una universidad. Hay diferencias significativas de las pruebas Saber 11 por género y esta prueba se encuentra muy correlacionada con la prueba Saber Pro. Los resultados de las pruebas Saber Pro en universidades oficiales son superiores a aquellos de las públicas.
Field Application of Tubing Deployed Inflow Control Devices ICDs to Repair Liner Failures in SAGD Completions: Diagnosis, Design, Deployment and Outcome
Authors: Saeedi Majid , Cowle Jason , Cross Ryan , Stevenson Jesse , Tuttle Aubrey 
Published: November 2019

Abstract
Liner failure is one of the key risks in operation of SAGD producers and is often associated with erosion as a result of steam production (Burke, L. et al. 2018). Among various intervention methods, tubing deployed inflow control devices (ICDs) have been used to remediate wells. In this paper, two field examples of using tubing ICDs are discussed, one inside a wire wrapped screen liner and the other inside a liner deployed ICD system.
Liner failures were diagnosed by analyzing the temperature data from fibre optics along with the performance indicators of the ESP pumps. Various remediation plans such as patching the failed intervals, using tubing ICDs or drilling a parallel lateral were considered. Using tubing deployed ICD systems along with blanked intervals was selected as the most practical solution to recover productivity from these wells. To size the ICDs and length of segments, a range of emulsion production volumes as well as estimated corresponding vapor and gas volumes were assumed. Furthermore, the risk of creating new hot points near the existing failed points or vapor producing intervals was considered.
The well workovers involved detailed planning of operations and services to effectively achieve cleanouts, maintain adequate inner wellbore diameter to run the swell packers and correlate DTS data with workover findings. The workover involved gauge runs, a jet-vac clean-out, a multi-finger caliper log and mud circulation of the wellbore for final solid removal to ensure successful installation of the new ICD systems.
The wells were put on production initially with low drawdown and slowly ramped up to let the packers set and sand to form bridges. After a few months of production, the wells were fully ramped up with production rate increasing 2 to 5 times the pre-workover rates. ESP pump performances is stable in both wells and the fibre optic temperature data show that failed liner intervals and hot points are well managed.
The intent of this paper is to share the processes and factors considered in using remedial ICDs and the learnings from the workover operations and startup of the wells.
Prognostics Thermal Well Management: A Review on Wellbore Monitoring and the Application of Distributed Acoustic Sensing DAS for Steam Breakthrough Detection
Authors: Soroush Mohammad , Roostaei Morteza , Fattahpour Vahidoddin , Mahmoudi Mahdi , Keough Daniel , Cheng Li , Moez Kambiz 
Published: November 2019

Abstract
Accurate prediction of flow regime and flow profile in wellbore is among the main interests of production engineers in the quest of optimizing wellbore production and increasing reliability of downhole completion tools especially in SAGD projects. This study introduces a methodology for wellbore monitoring by detecting flow phase and flow regime. In order to develop this method, an advanced multi-phase flow injection experiment was designed and commissioned.
A flow injection setup was developed to test distributed fiber optic sensor installation under different operating conditions, including multi-phase flow (oil, brine and gas), and flow fraction scenarios. Different signal processing methods were applied to extract meaningful features and filter the noise from the raw signals. A statistical analysis was performed to assess the trend of the driven data. Then, typical SAGD models were simulated to assess the results of experimental setup for scale-up purpose and determination of local breakthrough of steam along the well.
Results showed that the Distributed Acoustic Sensing (DAS) data contains different levels of signals for each phase and flow regime. We also found that some level of uncertainties is involved in relating the flow regime and DAS information which could be resolved by improving the sensor installation procedure. In addition, the application of data-driven machine learning methods was found necessary to interpret the signal patterns. Initial results have shown that steam breakthrough along the well can be detected using real time DAS high energy/frequency signals. It can be concluded that including the DAS along with Distributed Temperature Sensing (DTS) is necessary to provide a better picture of steam conformance and SAGD wellbore monitoring. The limitations of the current experimental setup restricted further conclusions regarding the hybrid DAS and DTS application.
This paper is a part of an ongoing project to address the application of the combined DAS and DTS in SAGD projects. The ultimate goal is a downhole monitoring system to oversee the flow phase, flow regime and sand ingress in thermal application. The next phase will address the required improvements for developing a flow loop to handle high temperatures, include sand production and mimic thermal operation conditions.
Geomechanical Simulations to Design Well Integrity
Authors: Yuan Yanguang , Boone Thomas J. 
Published: November 2019

Abstract
Rock deformation and fracturing is an important causal mechanism that can compromise well integrity. Geomechanical simulation is a valuable tool to investigate this mechanism and connect well tubular designs with reservoir development strategies. Utilizing relevant field examples, this paper describes a work flow in these regards.
Two example simulation approaches are described. One is to use a composite casing/cement/rock model in a reservoir of complex geology to compute maximum strain, dogleg severity, and ovality/restriction in the casing along the well trajectory. Different well design parameters, such as casing size, grade, and cement thickness, can be iterated against different reservoir production strategies. All these efforts are to arrive at an optimized design. The other approach is to calculate localized shear displacement along a weak plane that will be imposed on well tubulars during reservoir activities. The resulting design is optimized by altering well placement and stimulation/production schedules.
The above workflow has been proven in various field applications. Experience is shared in this paper. It is hoped this work can demonstrate that the optimal management of well integrity can be achieved by an integrated approach that designs appropriate tubulars and adjusts reservoir activities. Placing well tubulars in the context of rock deformation, geomechanical simulation is the best tool to connect the reservoir activities with the well tubular designs and therefore, can potentially offer a cost-effective well integrity management program.
SAGD Circulation Strategy Utilizing Flow Control Devices
Authors: Batias Jeremie , Ortiz Julian , Nespor Kristian 
Published: November 2019

Abstract
For ConocoPhillips, technology is a key driver and development accelerator to continuously improve its SAGD operations. The deployment of conventional Flow Control Device (FCD) technology in Surmont has allowed ConocoPhillips to realize shorter circulation times and higher oil production rates. These benefits have been realized while ensuring liner and well integrity.
Optimizing the well start-up process in SAGD has been a challenge at Surmont and in the industry in general. SAGD well start-up involves heating bitumen through a mostly conductive process to allow the SAGD mechanism to initiate. A recent breakthrough in the circulation strategy for wells equipped with FCDs at Surmont was developed and implemented by the ConocoPhillips Technology and Operation teams. This new approach has been possible by integrating FCD characterization and erosion testing with complex engineering principles such as convective heating, sand control, reservoir multiphase flow and wellbore flow dynamics. ConocoPhillips commenced the implementation of the new strategy in the field between 2015 and 2016 with great success. Benefits of this circulation strategy by fully utilizing the FCD technology are numerous, including a reduction of circulation duration, substantial increase in early time oil and liquid production and accelerated well ramp-up.
The paper begins by presenting the concept of this new circulation strategy. Then, details on various SAGD mechanisms and associated FCD physics are explained. Finally, field data is presented to illustrate the successful implementation of this strategy along with an analysis of the operating results.
Transcriptome sequencing of a keystone aquatic herbivore yields insights on the temperature-dependent metabolism of essential lipids
Authors: Windisch Heidrun Sigrid , Fink Patrick 
Published: November 2019

Abstract
Background: Nutritional quality of phytoplankton is a major determinant of the trophic transfer efficiency at the plant-herbivore interface in freshwater food webs. In particular, the phytoplankton’s content of the essential polyunsaturated omega-3 fatty acid eicosapentaenoic acid (EPA) has been repeatedly shown to limit secondary production in the major zooplankton herbivore genus Daphnia. Despite extensive research efforts on the biological model organism Daphnia, and the availability of several Daphnia genomes, little is known regarding the molecular mechanisms underlying the limitations in Daphnia related to dietary EPA availability. Results: We used RNA-seq to analyse the transcriptomic response of Daphnia magna which were fed with two different diets — each with or without supplementation of EPA — at two different temperature levels (15 and 20°C). The transcripts were mapped to the D. magna genome assembly version 2.4, containing 26,646 translations. When D. magna fed on green alga, changing the temperature provoked a differential expression of 2,001 transcripts, and in cyanobacteria-fed daphnia, 3,385 transcripts were affected. The supplementation of EPA affected 1,635 (on the green algal diet), or 175 transcripts (on the cyanobacterial diet), respectively. Combined effects for diet and temperature were also observed (669 for the green algal and 128 transcripts for the cyanobacterial diet). Searching for orthologous genes (COG-analysis) yielded a functional overview of the altered transcriptomes. Cross-matched transcript sets from both feed types were compiled to illuminate core responses to the factors temperature and EPA-supplementation. Conclusions: Our highly controlled eco-physiological experiments revealed an orchestrated response of genes involved in the transformation and signalling of essential fatty acids, including eicosanoid-signalling pathways with potential immune functions. We provide an overview of downstream-regulated genes, which contribute to enhance growth and reproductive output. We also identified numerous EPA-responsive candidate genes of yet unknown function, which constitute new targets for future studies on the molecular basis of EPA-dependent effects at the freshwater plant-herbivore interface.