bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clusty, the waveform-based network similarity clustering toolbox: concept and application to image complex faulting offshore Zakynthos (Greece)
Authors: Petersen G M , Niemz P , Cesca S , Mouslopoulou V , Bocchini G M 
Published: November 2020

SUMMARYClusty is a new open source toolbox dedicated to earthquake clustering based on waveforms recorded across a network of seismic stations. Its main application is the study of active faults and the detection and characterization of faults and fault networks. By using a density-based clustering approach, earthquakes pertaining to a common fault can be recognized even over long fault segments, and the first-order geometry and extent of active faults can be inferred. Clusty implements multiple techniques to compute a waveform based network similarity from maximum cross-correlation coefficients at multiple stations. The clustering procedure is designed to be transparent and parameters can be easily tuned. It is supported by a number of analysis visualization tools which help to assess the homogeneity within each cluster and the differences among distinct clusters. The toolbox returns graphical representations of the results. A list of representative events and stacked waveforms facilitate further analyses like moment tensor inversion. Results obtained in various frequency bands can be combined to account for large magnitude ranges. Thanks to the simple configuration, the toolbox is easily adaptable to new data sets and to large magnitude ranges. To show the potential of our new toolbox, we apply Clusty to the aftershock sequence of the Mw 6.9 25 October 2018 Zakynthos (Greece) Earthquake. Thanks to the complex tectonic setting at the western termination of the Hellenic Subduction System where multiple faults and faulting styles operate simultaneously, the Zakynthos data set provides an ideal case-study for our clustering analysis toolbox. Our results support the activation of several faults and provide insight into the geometry of faults or fault segments. We identify two large thrust faulting clusters in the vicinity of the main shock and multiple strike-slip clusters to the east, west and south of these clusters. Despite its location within the largest thrust cluster, the main shock does not show a high waveform similarity to any of the clusters. This is consistent with the results of other studies suggesting a complex failure mechanism for the main shock. We propose the existence of conjugated strike-slip faults in the south of the study area. Our waveform similarity based clustering toolbox is able to reveal distinct event clusters which cannot be discriminated based on locations and/or timing only. Additionally, the clustering results allows distinction between fault and auxiliary planes of focal mechanisms and to associate them to known active faults.
Spontaneous rupture of a coronary artery fistula presenting with post-exertional syncope and haemopericardium
Authors: Desai Manan H , Olivieri Laura J , Ramakrishnan Karthik V , Downing Tacy E 
Published: November 2020

Abstract
An 8-year-old with a known diagnosis of an asymptomatic coronary artery fistula (CAF) presented with exertional syncope and haemopericardium due to contained rupture of CAF. A transcatheter closure was attempted, but the fistula ruptured again prompting emergency surgical repair. Spontaneous rupture is a catastrophic complication of CAF and warrants a high index of suspicion, timely diagnosis and team management.
An unusual complication following stenting in a patient with chronic mesenteric ischaemia due to radiation therapy
Authors: Charfeddine Salma , Gueldiche Majdi , Feki Wiem , Bahloul Amine 
Published: November 2020

Abstract
The endovascular treatment is the first-line revascularization technique in chronic mesenteric ischaemia. We report a case of reperfusion haemorrhage complicating endovascular repair of severe stenosis of the superior mesenteric and coeliac arteries’ anatomic variant following abdominal radiation therapy. The haemorrhage resolved spontaneously after medical management, with successful outcome.
Identity, Land and Revolt in Egyptian Earth: An Ecofeminist Reading
Authors: Zakarriya Jihan 
Published: November 2020

AbstractThis article rethinks the representation of Egyptian rural culture and peasant participation in the nationalist struggle against British colonialism in Abdel Rahman al-Sharqaawi’s well-known novel Egyptian Earth, Al-Ard (1954). It specifically examines the concepts of identity, land, and revolt in Egyptian Earth from an ecofeminist perspective, relating peasants’ resistance against corrupt feudal-imperialist injustices in early twentieth-century Egypt to the dominant patriarchal cultural attitudes towards women’s and nature’s positions in the pre- and post-1952 revolutionary Egypt. It argues that although al-Sharqaawi’s Egyptian Earth gives marginalized Egyptian peasants the opportunity to participate in an important transitional period in the history of modern Egypt, it discusses the invisible psycho-cultural, environmental and social reasons and circumstances that hinder democratic transition in post-1952 revolution, with a particular focus on Egyptian countryside. Within this context, Egyptian villagers in Egyptian Earth are not just colonized people fighting colonial violence and discriminations through reconnecting to their land. They also stand for a patriarchal place and land suffering complicated, deep-seated problems of cultural isolation, sexism, and tribalism. In this way, Egyptian Earth develops ecofeminist ethics that condemn the colonial rule and the nationalist discourse, as both maintain hierarchical relationships between the urban and the rural, the male and the female, culture and nature, and authority and common people.
UMLS-based data augmentation for natural language processing of clinical research literature
Authors: Kang Tian , Perotte Adler , Tang Youlan , Ta Casey , Weng Chunhua 
Published: November 2020

AbstractObjectiveThe study sought to develop and evaluate a knowledge-based data augmentation method to improve the performance of deep learning models for biomedical natural language processing by overcoming training data scarcity.Materials and MethodsWe extended the easy data augmentation (EDA) method for biomedical named entity recognition (NER) by incorporating the Unified Medical Language System (UMLS) knowledge and called this method UMLS-EDA. We designed experiments to systematically evaluate the effect of UMLS-EDA on popular deep learning architectures for both NER and classification. We also compared UMLS-EDA to BERT.ResultsUMLS-EDA enables substantial improvement for NER tasks from the original long short-term memory conditional random fields (LSTM-CRF) model (micro-F1 score: +5%, + 17%, and +15%), helps the LSTM-CRF model (micro-F1 score: 0.66) outperform LSTM-CRF with transfer learning by BERT (0.63), and improves the performance of the state-of-the-art sentence classification model. The largest gain on micro-F1 score is 9%, from 0.75 to 0.84, better than classifiers with BERT pretraining (0.82).ConclusionsThis study presents a UMLS-based data augmentation method, UMLS-EDA. It is effective at improving deep learning models for both NER and sentence classification, and contributes original insights for designing new, superior deep learning approaches for low-resource biomedical domains.
Establishment ofAedes(Ochlerotatus)scapularis(Diptera: Culicidae) in Mainland Florida, With Notes on the Ochlerotatus Group in the United States
Authors: Reeves Lawrence E , Medina Johana , Miqueli Evaristo , Sloyer Kristin E , Petrie William , Vasquez Chalmers , Burkett-Cadena Nathan D 
Published: November 2020

AbstractAedes scapularis (Rondani), a widespread neotropical vector mosquito species, has been included in the mosquito fauna of Florida on the basis of just three larval specimens that were collected in the middle Florida Keys in 1945. Here, we report numerous recent collections of immature and adult Ae. scapularis from multiple locations in two counties of southern Florida. These specimens represent the first records of Ae. scapularis from mainland Florida and the first records of the species in the state since the initial detection of the species 75 yr ago. Collections of both larvae and adults across several years indicate that Ae. scapularis is now established in Broward and Miami-Dade Counties. These contemporary records of this species in Florida may represent novel dispersal and subsequent establishment events from populations outside the United States or a recent reemergence of undetected endemic populations. To confirm morphological identification of Ae. scapularis specimens from Florida, the DNA barcoding region of the cytochrome c oxidase subunit I gene (COI) was sequenced and compared to all other Ochlerotatus Group species from the United States, specifically Aedes condolescens Dyar and Knab (Diptera: Culicidae), Aedes infirmatus Dyar and Knab (Diptera: Culicidae), Aedes thelcter Dyar (Diptera: Culicidae), Aedes tortilis (Theobald) (Diptera: Culicidae), and Aedes trivittatus (Coquillett) (Diptera: Culicidae). Molecular assays and sequencing confirm morphological identification of Ae. scapularis specimens. Maximum likelihood phylogenetic analysis of COI and ITS2 sequences place Florida Ae. scapularis in a distinct clade, but was unable to produce distinct clades for Florida specimens of Ae. condolescens and Ae. tortilis.
Downregulation of Long Noncoding RNA TUG1 Attenuates MTDH-Mediated Inflammatory Damage via Targeting miR-29b-1-5p After Spinal Cord Ischemia Reperfusion
Authors: Jia Hui , Li Zhe , Chang Yi , Fang Bo , Zhou Yongjian , Ma Hong 
Published: November 2020

Abstract
Long noncoding RNAs and microRNAs (miRNAs) play a vital role in spinal cord ischemia reperfusion (IR) injury. The aim of this study was to identify the potential interactions between taurine upregulated gene 1 (TUG1) and miRNA-29b-1-5p in a rat model of spinal cord IR. The IR injury was established by 14-minute occlusion of aortic arch. TUG1 and metadherin (MTDH) knockdown were induced by respective siRNAs, and miR-29b-1-5p expression was modulated using specific inhibitor or mimics. The interactions between TUG1, miR-29b-1-5p, and the target genes were determined using the dual-luciferase reporter assay. We found that IR respectively downregulated and upregulated miR-29b-1-5p and TUG1, and significantly increased MTDH expression. MTDH was predicted as a target of miR-29b-1-5p and its knockdown downregulated NF-κB and IL-1β levels. A direct interaction was observed between TUG1 and miR-29b-1-5p, and knocking down TUG1 upregulated the latter. Furthermore, overexpression of miR-29b-1-5p or knockdown of TUG1 alleviated blood-spinal cord barrier leakage and improved hind-limb motor function by suppressing MTDH and its downstream pro-inflammatory cytokines. Knocking down TUG1 also alleviated MTDH/NF-κB/IL-1β pathway-mediated inflammatory damage after IR by targeting miR-29b-1-5p, whereas blocking the latter reversed the neuroprotective effect of TUG1 knockdown and restored MTDH/NF-κB/IL-1β levels.
The Cyclical Relation Between Chronic Pain, Executive Functioning, Emotional Regulation, and Self-Management
Authors: Caes Line , Dick Bruce , Duncan Christina , Allan Julia 
Published: November 2020

Abstract

Objective
To propose a new model outlining a hypothesized cyclical relation between executive functioning, emotional regulation, and chronic pain in adolescence and to highlight the likely importance of such a relation for self-management behavior and pain-related disability.

Methods
A review of the existing literature that critically explores the role of executive functioning in understanding chronic pain experiences and self-management in adolescence in order to develop the Cyclical model Of Pain, Executive function, emotion regulation, and Self-management (COPES).

Results
Growing evidence points towards a potential cyclical relation between chronic pain and impaired executive functioning, which forms the basis of COPES. The COPES model proposes that the relative immaturity of executive functioning in adolescence negatively influences their ability to engage with self-management, which in turn increases adolescents’ disability due to pain and contributes to the maintenance of chronic pain, which perpetuates the reduced capacity of executive functioning. The moderating influence of flexible parental support is hypothesized to offset some of these influences. However, the available evidence is limited due to methodological shortcomings such as large variety in executive functioning operationalization, reliance on self-report and cross-sectional designs.

Conclusions
It is anticipated that the COPES model will stimulate more systematic, theory-driven research to further our understanding of the links between executive functioning, chronic pain, self-management, and wellbeing. Such enhanced understanding has the potential to drive forward intervention development and refinement aimed at improving self-management uptake and adherence amongst adolescents with chronic pain.
Temperament and Health-Related Quality of Life in Newly Diagnosed Pediatric Inflammatory Bowel Disease
Authors: Shih Sharon , Cushman Grace , Reed Bonney 
Published: November 2020

Abstract

Objective
Health-related quality of life (HRQOL) is typically examined from a deficit standpoint, meaning that little is known about factors associated with higher HRQOL in pediatric illness samples. The aim of the current study was to investigate demographic, disease, and temperamental factors associated with child and parent-report of HRQOL in youth newly diagnosed with inflammatory bowel disease (IBD).

Methods
Participants included 52 youth ages 8–17 diagnosed with IBD and their caregivers who each completed ratings of the child’s HRQOL. Parents rated their child’s emotional reactivity, conceptualized as a temperamental risk factor, and adaptability, conceptualized as a temperamental protective factor. Disease symptoms were rated by youth, and physician global assessment of disease activity was obtained.

Results
HRQOL was rated lower by children and their parents as self-reported disease symptoms and parent-rated emotional reactivity increased. Conversely, total HRQOL was higher for children with higher parent-ratings of adaptability. In multiple regression analyses, higher levels of adaptability along with male sex and lower child-reported disease symptoms were associated with higher child and parent-reported HRQOL.

Conclusions
Higher HRQOL at time of diagnosis in pediatric IBD is associated with greater adaptability when accounting for variability due to child sex and disease symptoms. Consideration of temperament, including emotional reactivity and adaptability, may offer insight into patients’ typical ways of responding when stressed and provide preliminary information about factors related to post-diagnosis HRQOL. Attention should be given to both protective and risk factors to inform future intervention development, including strengths-based approaches.
Anxiety and Depression Correlates at Age 10 in Children Born Extremely Preterm
Authors: Moore Phoebe S , Mokrova Irina , Frazier Jean A , Joseph Robert M , Santos Hudson P , Dvir Yael , Hooper Stephen R , O’Shea T Michael , Douglass Laurie M , Kuban Karl C K 
Published: November 2020

AbstractObjective  Anxiety and depression rates are known to be elevated in prematurely-born children and adolescents. This prospective study examines demographic, academic, and physical health correlates of anxiety and depression symptoms in a sample of 10-year-old children who were born extremely preterm. Methods  Participants were 889 (51.2% male; 62.3% White) children who were born &lt;28 weeks gestation. Child and family demographic data were collected at birth. When the children were 10, parents (n = 871) and teachers (n = 640) rated the level of anxiety and depression in children through the Child Symptom Inventory-4. Child academic functioning was assessed via the Wechsler Individual Achievement Test-III. Parents completed questionnaires about child academic functioning and physical health issues. Data analyses were conducted with multivariate linear modeling. Results  Level of prematurity was significantly related to both parent and teacher reports of anxiety. Public health insurance and individualized education program (IEP) status were associated with both parent and teacher reports of depression. Hispanic ethnicity, public insurance, IEP status, and asthma were significantly associated with both parent-reported anxiety and depression. Gross motor impairment was associated with parent-reported anxiety and teacher-reported depression. Child obesity was associated with teacher reports of anxiety, while male sex was significantly related to teacher reports of depression. Conclusion  This pattern of findings may suggest hypotheses for future research on models of the development and persistence of anxiety and depression within this particularly vulnerable group of children.
Squamous cell carcinoma mimics small cell carcinoma of the lung: a case report
Authors: Kmeid Michael , Gillie Breanne , Asarian Armand , Xiao Philip 
Published: November 2020

Abstract
Squamous cell carcinomas (SCC) accounts for roughly 20% of lung cancers in the USA. The 2015 World Health Organization classification of lung tumors further categorizes SCC as three subtypes: keratinizing, non-keratinizing and basaloid variant. The non-keratinizing subtype is a poorly differentiated tumor that can present histologically in different ways, and one of which is a rare variant that strongly resembles small cell carcinoma. As a result, histological diagnosis alone is not sufficient to properly diagnose lung carcinomas. Immunohistochemistry has been increasingly used over the past few years to differentiate between lung tumors. The combination of morphological and immunohistochemical staining should be the mainstay for diagnosis of all lung carcinomas as more targeted therapies become more available.
GeoSentinel: past, present and future
Authors: Hamer Davidson H , Rizwan Aisha , Freedman David O , Kozarsky Phyllis , Libman Michael 
Published: November 2020

Abstract

Rationale for review
In response to increased concerns about emerging infectious diseases, GeoSentinel, the Global Surveillance Network of the International Society of Travel Medicine in partnership with the US Centers for Disease Control and Prevention (CDC), was established in 1995 in order to serve as a global provider-based emerging infections sentinel network, conduct surveillance for travel-related infections and communicate and assist global public health responses. This review summarizes the history, past achievements and future directions of the GeoSentinel Network.

Key findings
Funded by the US CDC in 1996, GeoSentinel has grown from a group of eight US-based travel and tropical medicine centers to a global network, which currently consists of 68 sites in 28 countries. GeoSentinel has provided important contributions that have enhanced the ability to use destination-specific differences to guide diagnosis and treatment of returning travelers, migrants and refugees. During the last two decades, GeoSentinel has identified a number of sentinel infectious disease events including previously unrecognized outbreaks and occurrence of diseases in locations thought not to harbor certain infectious agents. GeoSentinel has also provided useful insight into illnesses affecting different traveling populations such as migrants, business travelers and students, while characterizing in greater detail the epidemiology of infectious diseases such as typhoid fever, leishmaniasis and Zika virus disease.

Conclusions
Surveillance of travel- and migration-related infectious diseases has been the main focus of GeoSentinel for the last 25 years. However, GeoSentinel is now evolving into a network that will conduct both research and surveillance. The large number of participating sites and excellent geographic coverage for identification of both common and illnesses in individuals who have traversed international borders uniquely position GeoSentinel to make important contributions of travel-related infectious diseases in the years to come.
SAW homeodomain transcription factors regulate initiation of leaf margin serrations
Authors: Jeon Hyung-Woo , Byrne Mary E 
Published: November 2020

AbstractPlant leaves are the main photosynthetic organ of plants and they occur in an array of different shapes. Leaf shape is determined by morphogenesis whereby patterning of the leaf margin can result in interspaced leaf serrations, lobes, or leaflets, depending on the species, developmental stage, and in some instances the environment. In Arabidopsis, mutations in the homeodomain transcription factors SAW1 and SAW2 result in more prominent leaf margin serrations. Here we show that serrations appear precociously in the saw1 saw2 mutant. The pattern of auxin maxima, and of PIN1 and CUC2 expression, which form a feedback loop that drives serration outgrowth, is altered in saw1 saw2 and correlates with precocious serration initiation. SAW1 is not expressed in the outer epidermal cell layer where PIN1 convergence points generate auxin maxima. Instead, SAW1 is expressed on the adaxial side of the leaf and expression in this domain is sufficient for function. We suggest that SAW1 and SAW2 repress serration initiation and outgrowth by promoting the transition to a determinate fate in the leaf margin.
Influence of iron on growth and on susceptibility to itraconazole in Sporothrix spp
Authors: da Silva Hellwig Alessandra Helena , Pagani Danielle Machado , Rios Iasmin da Silva , Ribeiro Amanda Carvalho , Zanette Régis A , Scroferneker Maria Lúcia 
Published: November 2020

Abstract
We evaluated the growth and the susceptibility to oxidative stress of Sporothrix spp., exposed to different iron concentrations in culture medium, and the susceptibility of Sporothrix spp. to itraconazole, alone and in combination with to the iron chelator deferasirox. The results showed that the growth of S. brasiliensis isolates was more affected by iron availability in comparison to S. schenckii, but both fungal species conidia became more prone to oxidative stress when iron was added to culture medium. Conversely, the combination of itraconazole and deferasirox only resulted in synergism against a minority of S. schenckii isolates.
Mode angular degree identification in subgiant stars with convolutional neural networks based on power spectrum
Authors: Du Minghao , Bi Shaolan , Zhang Xianfei , Li Yaguang , Li Tanda , Shi Ruijie 
Published: November 2020

ABSTRACT
The identification of the angular degrees l of oscillation modes is essential for asteroseismology and it depends on visual tagging before fitting power spectra in a so-called peakbagging analysis. In oscillating subgiants, radial (l = 0) mode frequencies are distributed linearly in frequency, while non-radial (l ≥ 1) modes are p–g mixed modes that have a complex distribution in frequency that increases the difficulty of identifying l. In this study, we trained a one-dimensional convolutional neural network to perform this task using smoothed oscillation spectra. By training simulation data and fine-tuning the pre-trained network, we achieved 95 per cent accuracy for Kepler data.