bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infectious complications in children after transplantation of solid organs
Authors: Loskutova S. A. , Belousova Т. V. , Nikulina A. В. 
Published: November 2020

Objective: The objective is an optimization of medical support of children after transplantation of liver and kidneys based on analysis of frequency, etiology and nature of infectious complications.Methods: From 2017 to 2019, 40 transplantations of solid organs were performed in various medical institutions at 38 children, having lived in Novosibirsk region: 23 liver transplantation, 13 kidney transplantation and 2 single-stage transplantation of a part of the liver and the kidney. Imunosuppressive protocol components were lymphocyte non-exhaustion monoclonal antibodies, glucocorticosteroids, calcineurin inhibitor, mycophenolates. Besides immunosuppression right after the transplantation, 78.9 % of patients received Valgancyclovirum under inpatient treatment, and 65.8 % of patients continued taking it under outpatient treatment. In all cases, patients received Co-trimoxazole and Fluconazole for preventive purposes.Results: Right after the organs transplantation 44 cases of infectious complications of different etiology were detected. 39 infectious complications were diagnosed during early post-operative period, including 24 – after the liver transplantation, 15 – after the kidney transplantation. 17 longterm infectious complications were registered, in most cases (64.7 %) – after the liver transplantation. In general there is no significant difference in the frequency of complications after transplantations.Conclusions: Patients, having undergone the transplantation of solid organs, need a dynamic monitoring of markers of different infections. Taking into account persistent nature of infectious complications and high frequency of their occurrence, especially during the first six years, patients need a preventive prescription of Valgancyclovirum and Co-trimoxazole as well as prevention of urinary system infections after the kidney transplantation.
Epigenetic factors and optimization of the algorithm of differential diagnostics of gastrointestinal form of food allergy and intolerance to lactose in infants
Authors: Zernova E. S. , Grigoryan L. A. , Shishatskaya S. N. , Katenkova E. Yu. 
Published: November 2020

Objective: The objective is to analyze epigenetic and clinical features of course of the cow’s milk protein allergy (CMPA) and lactase deficiency (LD) in infants.Methods: We have assessed the factors contributing to the formation of CMPA and LD in children with calculation of attributable risk rate. Intensity of clinical symptoms was measured with CoMiSS.Results: The analysis according to CoMiSS showed the presence of general gastrointestinal symptoms in patients with CMPA and LD. The assessment of attributable risk factors gave the opportunity to create a scale of CMPA development.Conclusions: The invented scale will help to extract infants from the risk group and take complex of preventive measures.
Influence of nutrition on permanent dentition in children living in Vladivostok
Authors: Yatsenko A. K. , Trankovskaya L. V. , Pervov Yu. Yu. , Borisova E. A. , Gritsina O. P. 
Published: November 2020

Objective: The objective is to analyze the influence of nutrition on permanent dentition processes in children of early and middle childhood age.Methods: The study of the permanent dentition time periods in children going to municipal budgetary educational institutions of Vladivostok was performed. The sanitary audit of everyday nutrition was carried out. The causeeffect relations between nutrition and permanent dentition were identified.Results: First permanent teeth started erupting in girls in 4.5 y.o. The analysis showed children nutrition deficiency and imbalance in nutrient content of their diets. The portion of nutrition factor influence on permanent dentition in girls of early childhood age was 36.0 ±3.2Influence of nutrition on permanent dentition in children living in Vladivostok, in boys of early childhood age – 38.4±3.7 %, in girls of middle childhood age – 36.0±4.4 %, in boys of middle childhood – 36.0±0.2 %.Conclusion: The nutrient deficiency and dietary imbalance of a child serves as risk factors of the permanent dentition disorders. Developing a diet for children it is important to consider their physiological requirements at each age with mandatory inclusion of products containing sufficient amount of macroand microelements.
Vitamin D and proinflammatory cytokines in newborns from mothers with endocrine disorders
Authors: Zakharova I. N. , Kuryaninova V. A. , Verisokina N. Е. , Atanesyan R. A. , Klimov L. Ya. , Bobryshev D. V. , Zheleznyakova T. V. , Kuzmina E. M. , Simonyan A. V. , Petrosyan M. A. 
Published: November 2020

Objective: The objective is a comparative analysis of vitamin D content and level of proinflammatory cytokines in infants born by mothers with endocrine disorders, and in infants of women with normal body weight.Methods: The clinic-anthropometrical and laboratory observation of 78 children born in Stavropol Regional Clinical Perinatal Centre: 36 infants were born by women with obesity and 18 – by women with gestational diabetes mellitus associated with obesity, 24 – by women who did not have obesity and clinical and laboratory signs of intolerance to glucose (control group). The level of calcidiol and interleukin 1β and 6 were determined in blood serum.Results: The content of vitamin D in infants born by healthy women was higher than in infants born by mothers with gestational diabetes mellitus associated with obesity and by mothers with obesity. Infants born by mothers with obesity had higher level of proinflammotary cytokines than those of control group.Conclusions: Children, born by mothers with endocrine disorders, have lower level of calcidiol and require postnatal prevention of vitamin D deficiency. Also it is necessary to take vitamin D during the pregnancy to prevent complications in pregnancy and neonatal pathology.
Ability to biofilm formation in infectious agents isolated from patients of a large general children’s hospital
Authors: Savilov E. D. , Markova Y. A. , Nemchenko U. M. , Noskova O. A. , Chemezova N. N. , Kungurtseva E. A. , Dukhanina A. V. 
Published: November 2020

Objective: The study objective is to analyze biofilm formation in microorganisms isolated from patients of children’s hospital with severe purulent septic diseases.Methods: The ability to biofilm formation was studied in microorganisms isolated from 32 patients aged from 1 to 15 y.o. with sepsis, acute hematogenous osteomyelitis, peritonitis, and pneumonia in intensive care unit of regional general children’s hospital. Blood, phlegm, bronchial and oropharyngeal washings, wound fluid, peritoneal fluid served as specimens.Results: All tested strains have the ability to biofilm formation; moreover, the majority of them formed moderate biofilms.Conclusion: The common spread of biofilm infections can be related to the most important factors of preservation and distribution of microorganisms in health facilities which significantly limit preventive and therapeutic measures.
Prevention of pain syndrome and immediate postoperative complications in the surgical treatment of chronic hemorrhoids
Authors: Ishchenko V. N. , Krasnobaev A. E. , Grigoryuk A. A. 
Published: November 2020

Objective: To assess the efficacy of hemorrhoidectomy with Milligan-Morgan technique in the author’s modification.Methods: Results of surgical treatment of 558 patients aged 21–72 years with complicated hemorrhoids of III–IV stage were analyzed. The group of clinical comparison (207 patients) was operated according to standard scheme, the main group (351 patients) – according to author’s technology with modified technique for treating the hemorrhoid bolus using betamethasone.Results: When using the author’s technique, a more significant decrease in postoperative pain syndrome severity was achieved: injection analgesics were not required already in a day, and after 6 days the pain syndrome was stopped in all cases. Only three patients (0.9%) demonstrated an acute urinary retention up to two days. The group of clinical comparison maintained a longterm (up to three months) pain syndrome; postoperative urinary retention was registered in 38 cases (18.4%); 9 patients (4.3%) developed blood loss in the area of surgical intervention.Conclusions: Suggested technique of surgical treatment for hemorrhoids is quite effective, simple and can be implemented in any surgical inpatient facility.
Features of formation of the functional state of the central nervous system and cognitive abilities in children and adolescents of the school age
Authors: Setko N. P. , Bulycheva E. V. , Zhdanova O. M. 
Published: November 2020

Objective: The objective is to determine the features of formation of the functional state of the central nervous system (CNS) and cognitive abilities in children and adolescents of the school age.Methods: The study included 300 school children of general education institution of Orenburg. Functional state of CNS was evaluated with variational chronoreflexometry. Cognitive availabilities have been studied with proof-reading test, Landolt ring.Results: From 7–11 y.o. to 16–17 y.o., there was an increase by 1.5 times in parameters of CNS functional state. Students aged from 7–11 y.o. by 12–15 y.o. demonstrated decrease in processing speed by 1.5 times due to increase of cognitive activity to 1.8 times. From 12–15 y.o. by 16–17 y.o., on the contrary, there was an increase of information processing speed by 1.3 times and decrease of cognitive activity by 2.9 times.Conclusions: The detected features of formation of CNS functional state and cognitive abilities in children and adolescents can be taken into account in when organizing personality-oriented training in educational institutions in order to maintain and increase the level of mental performance and academic performance of students.
Modern pedagogical approaches to clinical training of students majoring 31.05.02 “Pediatrics” as a part of their independent activity
Authors: Sadova N. G. , Krukovich E. V. , Matienko L. E. , Mostovaya I. D. 
Published: November 2020

Objective: The objective is to analyze the organization of independent activity of students (IAS) as a part of training of pediatric students in a medical higher educational institution, to structure and to improve pedagogical techniques and to manage this activity.Methods: The study object was a management of clinical training for future professionals of the training program “Pediatrics” in Institute of pediatrics, PSMU.Results: The structure of IAS studying at clinical bases of Institute of Pediatrics includes three interconnected components: motivation and goal setting, independent activity and its management. The organization of IAS as a part of training of pediatric students in a medical higher educational institution was assessed. Pedagogical settings conducive to the development of professional competences in IAS of a medical higher educational institution exemplified by studying clinical disciplines of the specialty «Pediatrics».Conclusions: The efficacy of rational organization of IAS includes, primarily, formation of self-developing personality of a future professional able to solve urgent problems in their field, organize process of self-education.
Experience of practical training of future pediatricians in academic discipline of choice “Orfan diseases”
Authors: Martynovich N. N. , Barzunova T. V. , Semschikova Yu. P. 
Published: November 2020

A brief overview of problem relevance of rare (orfan) diseases in pediatrics and experience of Department of Pediatrics No. 1 of Irkutsk State Medical University on implementation of academic discipline of choice “Orfan diseases” into an academic process of the specialty 31.05.02 “Pediatrics”, relating to the variable part of block 1 «Disciplines (modules)».
The incidence of central serous chorioretinopathy in the population of Kazan: Results of a retrospective epidemiological analysis for 2009–2018
Authors: Аgliullin D. R. , Khasanova G. R. , Abdulaeva E. A. , Agliullina S. T. , Amirov A. N. , Kuskov A. N. , Kim A. A. , Rascheskov A. Yu. , Lipinskiy D. A. 
Published: November 2020

Objective: To assess the incidence of central serous chorioretinopathy (CSC) through the example of a large industrial Russian city.Methods: A retrospective analysis of CSC of Kazan population for 2009–2018 has been done.Results: From 2019 to 2018, 831 new cases of CSC were registered in Kazan. A statistically significant upward trend with growth rate 105.2% and accession rate 5.2% was typical for the annual track record. The mean age of patients was 50 years, the minimum age was 14 years, the maximum age was 87 years. A statistically significant upward trend was detected in track record of incidence in groups of 30–39-year-old and 40–49-year-old. Seasonal increase of the incidence was recorded in February, March, April, October, and November.Conclusions: The upward trend and seasonal prevalence are typical for longterm morbidity of CSC in Kazan. The highest morbidity rate of CSC and statistically significant upward trend of its incidence in track record were recorded in the age of 30–39.
Intravitreal Dexamethasone implant injection: Analysis of clinical efficacy and subjective satisfaction of patients with post-thrombotic macular edema
Authors: Sokolov K. V. , Smirnov A. K. 
Published: November 2020

Objective: Analysis of clinical efficacy and subjective satisfaction of patients with post-thrombotic macular edema after intravitreal administration of Ozurdex (dexamethasone).Methods: Thestudy included 33 patients (33 eyes) aged from 51 to 75 years with post-thrombotic macular retinal edema. The results were assessed before the intravitreal implantation, after one day, after a month, and three months later after the surgery.Results: The central retinal thickness significantly decreased on the first day after the surgery remaining almost the same after one and three months. The average retinal thickness had the similar dynamics. The macular volume reduced by 1.5 times in a day after the surgery. The maximum corrected visual acuity gradually increased over the time, remaining on average at the level of 0.5 diopters after one and three months. The subjective evalua‑ tion of quality of life (according to the VF-14 questionnaire) during the observation period progressively increased reaching 47.1 points by the end of the study.Conclusions: The study findings convincingly indicate the clinical efficacy of the intravitreal administration of dexamethasone and the subjective satisfaction of patients with the quality of treatment both in the early and late postoperative periods.
ANALISIS TINGKAT PELAYANAN PADA RUAS JALAN MAYOR SANTOSO KOTA PALEMBANG
Authors: Faritzie Hariman Al 
Published: November 2020

Melihat kondisi kota Palembang saat ini, jika ditinjau dari segi sarana dan prasarana transportasi sudah mulai berbanding terbalik. Dimana kebutuhan akan jalan tidak sebanding dengan banyaknya jumlah kendaraan yang ada. Sehingga hal ini akan menimbulkan dampak negatif terhadap pergerakan lalu-lintas, misalnya terjadi peningkatan volume lalu-lintas pada ruas-ruas jalan tertentu yang mengakibatkan terjadinya kemacetan panjang terutama pada jam-jam sibuk. Akibatnya, jarak yang sebenarnya singkat akan ditempuh dalam waktu yang cukup lama. Studi yang dilakukan pada penelitian ini bersifat riset yang dilakukan pada ruas jalan Mayor Santoso kota Palembang dengan tujuan untuk menghitung kapasitas dan tingkat pelayanan, yaitu dengan cara melakukan survey selama 1 jam (peak hour jam 09.51-10.51) yang mana dari survey ini didapatkan data volume lalu-lintas serta data geometrik jalan. Dalam pengolahan data dilakukan dengan metode Pedoman Kapasitas Jalan Indonesia (PKJI) 2014 dimana derajat kejenuhan (DJ=Q/C) sebagai indikator perilaku lalu-lintas pada ruas jalan Mayor Santoso Kota Palembang. Dari hasil pengolahan data survey didapatkan nilai arus kendaraan sebesar 1.316 skr/jam, kapasitas pada ruas jalan ini yaitu sebesar 4.656 skr/jam dan nilai rasio Q/C pada ruas jalan yaitu 0,28. Jadi nilai tingkat pelayanan untuk ruas jalan Mayor Santoso Kota Palembang pada level A yang artinya bahwa volume lalu-lintas pada ruas jalan Mayor Santoso Kota Palembang saat ini berada pada kapasitas arus bebas dengan volume lalu lintas mencapai 20% dari kapasitas, dan kecepatan kendaraan > 100 km/jam.
Kata Kunci : analisis kapasitas, kecepatan, tingkat pelayanan/LOS
ANALISIS PENERAPAN SISTEM MANAJEMEN KESELAMATAN DAN KESEHATAN KERJA (SMK3) PADA PROYEK KONSTRUKSI (STUDI KASUS PROYEK REVITALISASI DAN PERLUASAN DEPO KONTAINER DI PT. BHANDA GHARA REKSA DRIVE IV PALEMBANG)
Authors: Yuliansyah Feri , Arneta Dwi 
Published: November 2020

Keselamatan dan Kesehatan Kerja (K3) merupakan salah satu hal yang harus diperhatikan dalam pelaksanaan proyek konstruksi untuk mengurangi potensi kecelakaan kerja, dan meminimalisasi resiko kerugian moral maupun material, kehilangan jam kerja, maupun keselamatan manusia dan lingkungan sekitarnya yang nantinya dapat menunjang peningkatan kinerja yang efektif dan efisien.
Penelitian ini bertujuan untuk mengetahui ketersediaan fasilitas K3, menganalisa penerapan Sistem Manajemen Keselamatan dan Kesehatan Kerja (SMK3), dan Faktor-faktor apa saja yang menjadi penghambat penerapan K3.
Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan cara observasi dan penyebaran kuesioner. Instrumen penelitian yang digunakan berasal dari Peratutan Menteri PU No. 9 Tahun 2008 tentang pedoman SMK3 Konstruksi bidang pekerjaan umum.
Hasil dari penelitian adalah ketersedian APD dan Fasilitas K3 pada proyek Revitalisasi Dan Perluasan Depo Kontainer di PT. Bhanda Ghara Reksa (BGR) Divisi Regional IV Palembang sebesar 87,5% , sedangkan untuk pelaksanaan SMK3 sebesar 74,01%. Tidak disediakannya APD bagi pekerja dan kurangnya kepedulian dari para pekerja untuk menggunakan APD dengan baik menjadi faktor utama penghambat penerapan SMK3.
Features and algorithm of surgical behavior in osteoporotic vertebral fractures
Authors: Ferdinandov Dilyan , Yankov Dimo 
Published: November 2020

The aim of the current study is to present the possibilities for minimally invasive percutaneous procedures for surgical treatment of osteoporotic compression fractures of the vertebrae (OVCF), expressed in vertebroplasty and balloon kyphoplasty. We compare their therapeutic effect with that of conservative treatment and present conclusions from the world literature regarding the safety of these procedures.
Material and methods: We used data from our surgical experience for the last 10 years. We took into account the relevant literature from the global PubMed database and Google Scholar to present randomized clinical trials and meta-analyzes comparing OVCF treatment methods. We analyzed those who assessed the quality of life, pain, and complications of treatment.
Results: The world experience shows an excellent result in the short term from the minimally invasive percutaneous procedures. In the long term some authors note a significant overlap of the results with the conservative methods. All studies show a low risk profile in the surgical treatment, as well as comparable results between the two main procedures - vertebroplasty and balloon kyphoplasty.
Conclusion: Both vertebroplasty and balloon kyphoplasty have a statistically significant advantage in terms of final clinical indicators compared to conservative treatment at low and clinically justified risks. No statistically significant differences were found between the surgical techniques on most of the studied criteria, which would justify the significantly higher cost of kyphoplasty.
analisis penerapan keselamatan dan kesehatan kerja (k3) puskesmas di kabupaten semarang menggunakan re-aim framework
Authors: Prasetyowati Januar Diyah , Denny Hanifa Maher , Suroto Suroto 
Published: November 2020

Puskesmas sebagai sarana pelayanan kesehatan masyarakat menjadi tempat yang memiliki risiko tinggi terhadap terjadinya penularan penyakit. Keselamatan dan Kesehatan Kerja (K3) puskesmas ditujukan untuk dapat mengurangi risiko terjadinya kecelakaan kerja dan Penyakit Akibat Kerja (PAK) di puskesmas. Keselamatan dan Kesehatan Kerja (K3) Puskesmas di Kabupaten Semarang telah dilaksanakan sejak tahun 2010 namun hingga saat ini belum pernah dilakukan evaluasi tentang efektifitas pelaksanaan K3 puskesmas serta dampaknya terhadap peningkatan kualitas pelayanan kesehatan. Penelitian ini bertujuan untuk menganalisis penerapan K3 puskesmas di Kabupaten Semarang. Penelitian ini merupakan penelitian kualitatif yang menggunakan pendekatan lima dimensi RE-AIM framework untuk mengevaluasi penerapan K3 puskesmas di Kabupaten Semarang..Keselamatan dan Kesehatan Kerja (K3) puskesmas telah diterapkan di seluruh puskesmas yang diteliti, meskipun dalam penerapannya terdapat perbedaan pemahaman. Perbedaan dalam penerapan K3 puskesmas disebabkan oleh perbedaan proses sosialisasi yang dialami oleh puskesmas
Analisis perilaku pekerja seks komersial dalam memanfaatkan layanan kesehatan di LOKALISASI tegal panas kecemasan BERGAS Kabupaten Semarang
Authors: Sunarti Sunarti , Suratmi Tri , Darwis Darnialis 
Published: November 2020

ANALYSIS OF COMMERCIAL SEX WORKERS BEHAVIOR IN UTILIZING HEALTH SERVICES IN LOCALITATION DISTRICT OF SEMARANGABSTRACT Sexually transmitted infections are diseases caused by bacteria, viruses, parasites, or fungi that are transmitted from one person to another through sexual contact or relationship. Most sufferers in Indonesia are those of productive age aged 20-39 years. In Indonesia the number of cases of STIs with enforcement of diagnoses based on the syndrome approach and laboratory examination according to the highest risk group were female sex workers with a total of 8,765 cases. Commercial sex workers are at risk of contracting sexually transmitted diseases. STIs can increase the risk of contracting HIV (Human Immunodeficiency Virus) infection, making them have the opportunity to get STIs with their jobs serving many different customers. This study aims to analyze the behavior of commercial sex workers in utilizing health services in Tegal Panas Localization.The research design used was descriptive qualitative. The subjects in this study were six commercial sex workers and three key informants (Health and Pimps). The object in this study is the behavior of sex workers in utilizing health services. The methods in this study were observation, in-depth interviews and Focus Group Discussion conducted at Tegal Panas Localization using data analysis, namely content analysis and data reduction.Knowledge of sex workers such as signs of symptoms and types of STIs is still lacking, but is good enough in terms of prevention and treatment of STIs, most of them protect themselves by taking antibiotics and washing genitals with antiseptic. The use of condoms is based on agreements with customers and health services that have not been utilized by all existing commercial sex workers in Localization. Keyword : Sex Workers, Behavior, STIs