bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Kinerja Bisnis Internal Perusahaan Pupuk Organik Cv Mulia Organik Turi Sleman
Authors: Sunardi Sunardi , Akimi Akimi 
Published: October 2019

The purpose of this study was to analyze the internal business performance of organic fertilizer companies, CV Mulia Organik during the 2014-2016 period. This research is a case study, the selection method uses purposive sampling. While respondents consisted of nine employee respondents and two respondents of CV Mulia Organik customers. Data collection methods are obtained from secondary data secondary data with documentation. This research was conducted using an internal business perspective with Supply Lead Time (SLT) and capacity calculations. The results obtained result that overall internal business performance of the CV Mulia Organic, it’s performance not good.
APLIKASI E-SURVEY BERBASIS WEB PADA STMIK DUMAI
Authors: Naim Nasrul , Ridarmin Ridarmin , Widodo Pulla Pandika 
Published: October 2019

<p><em>Telah dilakukan Penelitian pada STMIK Dumai, dimana permasalahan yang dijadikan dasar dalam penulisan skripsi ini yaitu membuat aplikasi yang dapat memudahkan pengguna untuk mahasiswa melakukan e-survey terhadap pelayanan kampus STMIK Dumai. Oleh karena itu, dirancang sebuah aplikasi yang dapat memudah pengguna untuk melakukan survey. Dengan adanya Aplikasi E-Survey Berbasis Web ini, maka memudahkan mahasiswa untuk melakukan survey terhadap pelayanan kampus STMIK Dumai sudah dilakukan terkomputerisasi dan online.</em></p><p> </p><p><strong>Kata Kunci : </strong>E-Survey, Aplikasi, Web, Pelayanan</p>
APLIKASI SISTEM PAKAR UNTUK DIAGNOSA PENYAKIT HERNIA MENGGUNAKAN METODE FORWARD CHAINING DAN BACKWARD CHAINING
Authors: Kurniawan Rahmad , Falah Nurul 
Published: October 2019

<p><em>P</em><em>enyakit hernia</em><em> merupakan penyakit </em><em>yang mana gejalanya kurang dipahami oleh kebanyakan orang. Penyakit ini bisa menyerang pada semua usia, baik anak-anak hingga orang tua. Selain itu, kurangnya dokter spesialis, khususnya untuk daerah Kota Dumai, serta belum adanya suatu sistem yang digunakan untuk mendiagnosa penyakit hernia, juga menjadi penyebab kurangnya keinginan masyarakat untuk memeriksakan gejala-gejala yang telah dialami.Sistem untuk mendiagnosa penyakit hernia ini adalah suatu sistem terkomputerisasi yang dapat memberikan solusi yang maksimal. Dalam menyelesaikan sistem ini dapat digunakan dua metode, yaitu metode forward chaining dan metode backward chaining.</em><em>Oleh karena itu, dirancang sebuah aplikasi sistem pakar yang digunakan sebagai solusi permasalahan tersebut. Aplikasi ini dibuat dengan menggunakan bahasa pemrograman Visual Basic 6.0, serta menggunakan database MySQL. </em><em>Hasil dari uji coba aplikasi sistem pakar diagnosa penyakit hernia ini adalah mempermudah melakukan diagnosa penyakit hernia serta memberikan pencegahan serta solusi dari penyakit tersebut.</em><em></em></p><p> </p><p><strong><em>Kata Kunci :</em></strong><em> Sistem Pakar, Forward Chaining, Backward Chaining, Hernia</em></p>
IMPLEMENTASI PROXY SERVER DI SMP NEGERI 1 DUMAI MENGGUNAKAN SISTEM OPERASI CLEAROS
Authors: Irawan Budi , Khumaini Hayatullah 
Published: October 2019

<p><em>Telah dilakukan penelitian pada SMPN 1 Dumai, dimana permasalahan selama ini penggunaan internet pada SMPN 1 Dumai masih mengguakan sharing hub, jadi setiap client yang online langsung terhubung ke internet tanpa adanya perantara yang mengamankan lalulintas data yang seringkali memboroskan pemakain bandwidth. Maka dalam penelitian ini akan dibuat sebuah proxy server yang bertindak sebagai caching content dan filter yang dapat menghemat pemakain bandwidth, membersihkan pop up yang ada pada halaman web dan menyaring halaman yang memiliki unsur pornografi sehingga semua client yang online akan nyaman dan tidak memerlukan waktu yang lama untuk mengakses website yang pernah diakses karena sudah tersimpan pada server local yang ada di proxy. Tujuan pembuatan proxy server pada SMPN 1 Dumai dengan sistem operasi ClearOS 6.8 adalah menciptakan sebuah server yang dapat menyimpan beberapa file dan juga website yang telah di filter agar dapat diakses oleh semua client</em><em> </em><em>dalam lingkungan SMPN 1 Dumai dengan aman.</em><em> </em><em>Dengan adanya proxy server diharapkan akan memebantu dan memudahkan client dalam mengakses website yang sehat dan baik. </em></p><p> </p><p><strong>Kata kunci</strong> <em>: Linux ClearOS, Proxy Server, caching, filter</em><em></em></p>
AGN All the Way Down? AGN-like Line Ratios Are Common in the Lowest-mass Isolated Quiescent Galaxies
Authors: Dickey Claire Mackay , Geha Marla , Wetzel Andrew , El-Badry Kareem 
Published: October 2019

Abstract
We investigate the lowest-mass quiescent galaxies known to exist in isolated environments (

; 1.5 Mpc from a more massive galaxy). This population may represent the lowest stellar mass galaxies in which internal feedback quenches galaxy-wide star formation. We present a Keck/Echelle Spectrograph and Imager long-slit spectroscopy for 27 isolated galaxies in this regime (20 quiescent galaxies and 7 star-forming galaxies). We measure emission line strengths as a function of radius and place galaxies on the Baldwin–Phillips–Terlevich (BPT) diagram. Remarkably, 16 of 20 quiescent galaxies in our sample host central active galactic nucleus (AGN)-like line ratios. Only five of these quiescent galaxies were identified as AGN-like in the Sloan Digital Sky Survey due to a lower spatial resolution and signal-to-noise ratio. We find that many of the quiescent galaxies in our sample have spatially extended emission across the non-star-forming regions of BPT-space. While quenched galaxies in denser environments in this mass range often show no evidence for AGN activity, a significant fraction of quiescent galaxies in isolation host AGNs despite their overall passive appearances.
A short, 8-week course of imiquimod 5% cream versus podophyllotoxin in the treatment of anogenital warts: A retrospective comparative cohort study
Authors: Nicolaidou Electra , Kanelleas Antonios , Nikolakopoulos S. , Bezrodnii G. , Nearchou E. , Gerodimou M. , Papadopoulou-Skordou E. , Paparizos V. , Rigopoulos D. 
Published: October 2019

Background:
Studies comparing head-to-head treatment modalities for anogenital warts are lacking.

Aim:
We sought to compare a short, 8-week course of imiquimod 5% cream to versus the standard 4 week course of podophyllotoxin in the treatment of anogenital warts and to assess factors that may affect response to treatment.

Methods:
This was a retrospective cohort study. We reviewed medical files of otherwise healthy patients with a first episode of anogenital warts who were treated with either a short, 8-week course of imiquimod or the standard 4-week course of podophyllotoxin. Inverse probability of treatment weighted (IPTW). Logistic regression was employed to evaluate factors that may affect response to therapy.

Results:
The study included 347 patients. In patients with lesions on dry, keratinized anatomical sites, the complete clearance rates were 7.6% for imiquimod and 27.9% for podophyllotoxin (P < 0.001). In patients with lesions on moist, partially keratinized sites, no difference between the treatments was revealed. Significant predictors of > 50% reduction in wart area were location of lesions [odds ratio (OR) (95% confidence interval (CI)): 3.6 (1.84–7.08), P = 0.0002] for “partially keratinized” versus “keratinized” sites and treatment used [OR (95% CI): 1.79 (1.08–2.97), P = 0.024] for podophyllotoxin versus imiquimod.

Limitations:
The retrospective design of the study was a limitation that we mitigated against with the use of IPTW logistic regression.

Conclusion:
A standard 4 week course of Podophyllotoxin was more effective than an 8-week course of imiquimod only for lesions on keratinized sites. Treatment with podophyllotoxin and location of lesions on partially keratinized sites were independent predictors of >50% reduction in wart area.
Efficacy of salicylic acid peel in dermatophytosis
Authors: Saoji Vikrant , Madke Bhushan 
Published: October 2019

Background:Treatment of dermatophytosis is becoming costlier and challenging.Aims and Objectives:To study the efficacy of salicylic acid peel in dermatophytosis.Methods:Twenty-five patients (20 males and 5 females) having dermatophytosis with positive potassium hydroxide (KOH) mounts were enrolled in the study. Salicylic acid 30% was applied over the lesions weekly for 4 weeks, thereafter patients were followed up weekly for 4 weeks.Results:Of the 25 patients, 22 (88%) patients showed clinical and microbiological cure 1 week after the last application, while the remaining 3 patients were nonresponders. Nine (41%) patients of the 22 responders showed recurrences indicating that 4 weeks’ treatment is not sufficient in some patients to eradicate fungus and may require longer treatment.Limitations:A relatively small sample size and lack of long-term follow-up are the shortcomings of our study.Conclusion:Salicylic acid peel is a cheap and useful option in the treatment of dermatophytic infection.
Explaining Value vs. Growth Fallacy: An Empirical Study for Indian Market
Authors: Vasishth Vibhuti , Sehgal Sanjay 
Published: October 2019

Prior research describes value and growth characteristics on the same continuum. We attempt to test this for the Indian market. Similar to past studies, our results confirm the presence of value premium. But unlike previous literature, superior profits in growth strategy are also observed. This leads us to believe that value and growth are different dimensions. Value premium may be explained by investor overreaction. Whereas, growth premium arises due to future growth potential of high growth stocks.Negative correlation is observed between value and growth premiums which can be used by investors for achieving time diversification. We find that higher profits can be achieved by combining value and growth. The returns on univariate value or growth strategies are explained by either Capital Asset Pricing Model or Fama-French three factor model. The returns on bivariate strategies based on both value and growth remain unexplained even by Fama-French five factor model level.
Umbilical Cord Teratomas Associated With Congenital Malformations
Authors: Adams Kristen V. , Bernieh Anas , Morris Robert W. , Saad Ali G. 
Published: October 2019

Context.—Congenital mature teratomas of the umbilical cord are extremely rare and pose a challenge in prenatal diagnosis. Mature teratomas are defined as tumors composed of mature tissues derived from more than 1 germ cell layer. The tumor often shows solid and cystic components, which adds to the difficulty of prenatal diagnosis. Although benign, mature teratomas of the umbilical cord are commonly associated with congenital malformations of the fetus with variable severity and rarely, with chromosomal abnormalities.Objective.—To review the clinical, radiologic, gross, and histologic features of umbilical cord teratoma; its differential diagnosis; and to emphasize the increased risk of associated congenital malformations.Data Sources.—Umbilical cord teratoma cases published in the literature.Conclusions.—Umbilical cord teratomas are difficult to diagnose by imaging studies alone and require histopathologic examination for diagnosis. Given the increased risk of associated anomalies and malformations, the finding of umbilical cord teratoma should trigger a detailed and comprehensive evaluation of the neonate for additional abnormalities.
Ameliorating Effect of Moringa against Liver and Kidney Injury Induced by Monosodium Glutamate
Authors: El-Gharabawy Rehab M. , Ahmed Amira S. , Al-Adhadh Thara I. 
Published: October 2019

Background: Monosodium glutamate (MSG) produces adverse and damaging effects in different organs like liver and kidneys. Moringa has ameliorating effect on kidney and liver injury induced by monosodium glutamate.
Objective: To study the ameliorating effect of moringa against rats liver and kidney injury induced by monosodium glutamate.
Design: Prospective study.
Setting: College of Pharmacy, Qassim University.
Materials and Methods: This study was performed on 20 male rats and equally divided into 4 groups. The first group was control group, second group was moringa group, third group was MSG group and forth group was MSG plus moringa group. We determined liver function, albumin, total protein, kidney function, electrolytes and histopathological examination of tissue.
Main Outcome Results: Moringa has ameliorating effect on kidney and liver injury induced by monosodium glutamate.
Sample Size: A total of 20 malerats.
Results: There was a significant increase in the levels of serum aspartate transaminase (AST) and alanine transaminase (ALT), alkaline phosphatase (ALP), urea and creatinine. Significant decrease in the levels of albumin, total proteins and sodium levels in rats treated with monosodium glutamate. Kidney sections revealed normal structure of glomeruli and renal tubules as control group, liver revealed good improvements and mild cellular infiltrations were observed in rats treated with MSG and moringa group.
Conclusion: Moringa causes ameliorating effect on kidney and liver injury induced by monosodium glutamate in rats.
Limitation of the Study: Few studies about the protective effect of Moringa against toxic effect of MSG. So we need to focus on its beneficial effect against toxicity induced by MSG.
Quantitative Comparison of Oral Site-specific DNA Isolates Reveals Differential Outcomes
Authors: Carr Graydon , Alexander Arvin , Dionisio Kevin , Kingsley Karl 
Published: October 2019

Introduction: More and more evidence has accumulated that suggests salivary sampling may provide direct analysis of oral conditions and microbial constituents, but may also be useful in the diagnosis and early detection of other chronic diseases. Although multiple methods of oral sampling currently exist, some methods are prohibitively expensive or based upon technologies not ubiquitously available at public health centers or state-funded colleges. This study provides a comparative analysis of DNA concentrations and quality from five specific oral sites derived using sterile paper points, including the gingival crevice between the upper central incisors, biofilm of the upper first molar, lingual incisor, and the dorsum of the tongue for comparison with unstimulated saliva collection.
Methods: This study analyzed previously collected unstimulated saliva and paper point samples. In brief, DNA was isolated from each using TRIzol (phenol: Chloroform) extraction and DNA quantification and quality was measured using a NanoDrop spectrophotometer at 260 and 280 nm.
Results: Analysis of Paper Point (PP) biofilm sampling sites from upper first molar, lower incisor, and dorsum of the tongue revealed similar average DNA concentrations, ranging between 14,342 ng/uL and 14,402 ng/uL (p=0.9851). Although variations were observed between different patients, samples from different oral sites within the same patient were strikingly similar, R=0.8355. Comparison of DNA isolated from fluids, gingival crevicular fluid (GCF) and unstimulated saliva revealed average DNA concentrations that were similar to the biofilm sampling sites (14,686 ng/uL and 13,743 ng/uL, respectively), which were not significantly different from one another (p=0.7893). DNA concentrations ranged considerably between patients (low = 4,410 ng/uL; high = 48,783 ng/uL), but were most similar with different samples (GCF, saliva) from the same patient (Pearson’s R=0.6979). In addition, DNA purity measured by A260:A280 nm absorbance did not reveal any significant difference among sampling sites (range 1.62 – 1.70; p=0.427).
Discussion: Although many methods are available to provide oral sampling, simple and low-cost methods such as paper point sampling, unstimulated saliva collection and buccal swabs may represent tools that provide sufficient DNA quality and quantity for molecular screening. In addition, although heterogeneity between patient samples will always be present – samples from various oral sites within the same patient may provide roughly equivalent DNA samples for further screening and molecular analysis.
Cerebellar connectivity in Parkinson's disease with levodopa‐induced dyskinesia
Authors: Yoo Han Soo , Choi Yong Ho , Chung Seok Jong , Lee Yang Hyun , Ye Byoung Seok , Sohn Young H. , Lee Jong‐Min , Lee Phil Hyu 
Published: October 2019

AbstractObjectiveThe precise pathogenesis or neural correlates underlying levodopa‐induced dyskinesia (LID) remains poorly understood. There is growing evidence of the involvement of the cerebellum in Parkinson's disease (PD). The present study evaluated the role of motor cerebellar connectivity in determining vulnerability to LID.MethodsWe enrolled 25 de novo patients with PD who developed LID within 5 years of levodopa treatment, 26 propensity score‐matched PD patients who had not developed LID, and 24 age‐ and sex‐matched healthy controls. We performed a comparative analysis of resting‐state functional connectivity (FC) between the motor cerebellum and whole brain between the groups.ResultsThe patients with PD had increased FC bewteen the motor cerebellum and posterior cortical and cerebellar regions, while no gray matter regions had decreased FC with the motor cerebellum compared to the control participant. The patients with PD who were vulnerable to the development of LID had a significantly higher FC between the motor cerebellum lobule VIIIb and the left inferior frontal gyrus than those who were resistant to LID development. The connectivity of the motor cerebellum and left inferior frontal gyrus was negatively correlated with the latency from PD onset to the occurrence of LID.InterpretationIncreased FC between the motor cerebellum and left inferior frontal gyrus in de novo patients with PD could be an important determinant of vulnerability to LID.
Over 1000‐Fold Enhancement of the Unidirectional Photoluminescence from a Microsphere‐Cavity‐Array‐Capped QD/PDMS Composite Film for Flexible Lighting and Displays
Authors: Yang Lixue , Li Lin , Wang Qiang , Xing Cheng , Ma Lin , Zeng Yong , Zhao Yan , Yan Yinzhou 
Published: October 2019

AbstractThe development of quantum dot (QD) composite films for lighting and displays is of great importance because of their exceptional mechanical flexibility, chemical stability, and optical tunability. Generally, QDs are attached to plasmonic nanostructures to enhance their photoluminescence (PL) emission. However, plasmonic QD composite films suffer from deteriorated inherent quantum yields and lower enhancement ratios due to variations in the refractive index and dielectricity in the composites. Herein, the use of a dielectric microsphere cavity is reported to realize over 1000‐fold enhancement of the PL in CdSe/ZnS QD/polydimethylsiloxane films with a highly unidirectional emission angle of ≈9°. The field regulation by the optical whispering‐gallery resonance and directional antenna effect at the microscale is revealed to interpret the PL enhancement mechanism. Additionally, the microsphere cavity allows for the enhancement of white‐light emission in the RGB‐QD hybrid composite film. The present work inspires a straightforward strategy for boosting the light efficiency in QD composite films, with promising applications in flexible lighting/display devices.
Scalable Synthesis of the Transparent Conductive Oxide SrVO3
Authors: Shoham Lishai , Baskin Maria , Han Myung‐Geun , Zhu Yimei , Kornblum Lior 
Published: October 2019

AbstractThe correlated metal SrVO3 is an attractive earth‐abundant transparent conducting oxide (TCO), a critical component of many optoelectronic and renewable energy devices. A key challenge is to synthesize films with low resistivity, due to the prevalence of defects that cause electron scattering. In addition to the material's promise as a TCO, its interesting correlated‐electron physics is often obscured by a high defect concentration, which inhibits its further development into new types of devices. A route to synthesize low‐defect SrVO3 films by scalable, industry‐compatible molecular beam epitaxy (MBE) is demonstrated. The resulting films consistently exhibit a residual resistivity ratio in the excess of 10 and room temperature resistivity as low as 32 µΩ cm, an indication of their high quality and potential for applications. Analysis of the structural and electronic properties of SrVO3 films provides insights that are applicable to other conductive oxides, and highlights a route for further improvement in their quality and low temperature performance. MBE is the only growth method that allows atomically abrupt epitaxial interfaces between oxides and semiconductors such as Si and GaAs. Such interfaces are essential for efficient charge transport that is at the heart of the performance of most optoelectronic and solar devices.
From directed evolution to computational enzyme engineering—A review
Authors: Chowdhury Ratul , Maranas Costas D. 
Published: October 2019

AbstractNature relies on a wide range of enzymes with specific biocatalytic roles to carry out much of the chemistry needed to sustain life. Enzymes catalyze the interconversion of a vast array of molecules with high specificity—from molecular nitrogen fixation to the synthesis of highly specialized hormones and quorum‐sensing molecules. Ever increasing emphasis on renewable sources for energy and waste minimization has turned enzymes into key industrial workhorses for targeted chemical conversions. Modern enzymology is central to not only food and beverage manufacturing processes but also finds relevance in countless consumer product formulations such as proteolytic enzymes in detergents, amylases for excess bleach removal from textiles, proteases in meat tenderization, and lactoperoxidases in dairy products. Herein, we present an overview of enzyme science and engineering milestones and the emergence of directed evolution of enzymes for which the 2018 Nobel Prize in Chemistry was awarded to Dr. Frances Arnold.
Worldwide asthma epidemiology: insights from the Global Health Data Exchange database
Authors: Mattiuzzi Camilla , Lippi Giuseppe 
Published: October 2019

BackgroundEnhanced focus on primary care provision is essential for lowering the risk of asthma exacerbation and complications, as well as for decreasing asthma‐related hospitalizations and deaths. This article provides an update on current worldwide epidemiology of asthma.MethodsWorldwide epidemiologic information on asthma was obtained through electronic searches in the Global Health Data Exchange (GHDx) database.ResultsIn 2017, the incidence of asthma was 43.12 million new cases/year (0.56%), while in that same year, prevalence and mortality accounted for 272.68 million cases (3.57%) and 0.49 million deaths (0.006%), respectively. Although the number of asthma cases significantly increased during the last 25 years, disability‐adjusted life years (DALYs) and deaths constantly declined. After adjustment of asthma incidence, prevalence, and DALYs for worldwide demographic variation, no significant changes could be seen during the last 25 years, while asthma mortality significantly declined during the same period. Asthma incidence peaks before the age of 5 years, whereas prevalence and DALYs peaks are observed between 0 and 14 years. DALYs also display a second peak, between 45 and 74 years. Asthma mortality increases with aging, reaching the peak after 80 years. The epidemiologic burden and mortality of asthma are constantly higher in women than in men. An inverse, highly significant correlation can be found between sociodemographic index and asthma incidence (r = −0.98) or mortality (r = −0.96).ConclusionAlthough the worldwide burden of asthma remains high, incidence and prevalence are not apparently translating into an escalating clinical and economic burden in terms of health loss and deaths.