bluuebunny/crossref_metadata_2025_split huggingface dataset:
Status constraint and lifestyle transition: a latent class analysis of health-related lifestyles among different social strata in China
Authors: Wang Fuqin 
Published: December 2019

AbstractThe present study uses data from the Chinese General Social Survey (CGSS) to develop a multidimensional measure for the healthiness of Chinese citizens’ lifestyles. A latent class analysis reveals variety in Chinese people’s lifestyles. Three categories are identified: the healthy, the mixed, and the risky. People with higher socio-economic status (SES) are polarized between the healthy and the risky lifestyles, while those with lower SES tend to have a more mixed lifestyle. Generally speaking, Chinese people’s lifestyles are in constant change. Located in an advantageous social-structural position, members of the upper strata manage to choose the lifestyle beneficial to their health. At the same time, however, they are influenced by western lifestyles. Members of the lower strata are more constrained by social-structural status.
Economic evaluation of alternative technologies to mitigate Sulphur emissions in maritime container transport from both the vessel owner and shipper perspective
Authors: Mohseni Seyed Abolfazl , van Hassel Edwin , Sys Christa , Vanelslander Thierry 
Published: December 2019

AbstractInternational maritime shipping is confronted from 2006 onwards with regulation until 2030 by different policy actors (i.e. International Maritime Organization, hereafter IMO), the EU) in order to improve the ecological performance of maritime shipping, and will face more so in the future. Many of these regulations concern the reduction of air pollution of vessels both globally and in particular in so-called Emission Control Areas (ECA’s).In this research, the economic impact of alternative technologies in order to reduce the Sulphur emissions in existing ECA zones is analyzed both from the perspective of the vessel owner, as well as for the evaluation of generalized chain cost, hence from the shipper point of view.The container carriers can choose different methods to comply with the new regulations, such as switching fuel types (Liquefied Natural Gas (LNG), Marine Diesel Oil (MDO)) or opting for innovative technologies like installing scrubber systems.The goal of this research is twofold: first, to discover alternative available technologies to mitigate Sulphur emissions according to the literature; second, to evaluate economically the selected technologies both from vessel owners and shippers perspectives.In order to study this, an update of an existing model is used. The added value of the extended model is threefold: calculating the generalized chain cost of transporting a container from the origin (US and Asia) to a destination in the EU, incorporating in the model the different ECA zones in the world and integrating more detailed fuel cost calculations and capital cost for different engine types or technologies used.The methodology used in this research is an extension of an existing model which is updated for the purpose of this research. This update includes a new functionality to allow calculating the vessel owner cost for different fuel types and propulsion systems (Heavy Fuel Oil or HFO, MDO and LNG). Next to that, more maritime distance data is collected containing the distance sailed in ECA zones. This means that for each port-to-port combination, in the total maritime distance database in the model, this additional information is added. Based on this information, the fuel cost can be calculated when a vessel is sailing in ECA zones using either MDO, LNG or HFO (including a scrubber).The research is particularly interesting for logistics operators, legislation regulators and academia. The extended model allows calculating the best economic solutions for selected routes. For logistics operators and in particular for shippers, the results allow making the most rewarding investments from an economic point of view and affirm the importance of different technologies on the generalized chain cost. The results indicate that the price of the different fuels (and the spread between them) displays an important factor in the overall outcome.
Prevalence of herpes simplex, varicella zoster and Cytomegalovirus in tumorous and adjacent tissues of patients, suffering from colorectal cancer in Iran
Authors: Tavakolian Shaian , Goudarzi Hossein , Kazeminezhad Behrang , Faghihloo Ebrahim 
Published: December 2019

AbstractBackgroundColorectal cancer (CRC) can be considered as a result of multiple risks factors, and the significant role of infectious ones, especially viral diseases could not be underestimated. Despite endorsed attempts to identify the accelerating effects of different herpes viridea, such as HSV-1, HSV2, VZV and CMV on the deterioration of different kinds of malignancy, the relationship between these viruses and CRC have not successfully been understood. Taking advantages of these facts, we assessed the role of these viruses on CRC progression.MethodsIn this case-control study, 88 cancerous specimens and 70 their adjacent paraffin-embedded tissues from Modares Hospital between 2011 and 2019 were collected. We extracted the DNA of each tissue and investigated the presence of HSV-1, HSV2, VZV and CMV.ResultsOur data indicated the presence of HSV-1 DNA in the three control samples; however, we could not find an obvious relationship between HSV2, VZV, CMV infection and this type of cancer. The presence of HSV-1 DNA in control tissues introduced HSV-1 as a probable factor for the killing of colorectal cancer cells.Conclusionswe supposed that HSV-1 can function as an inhibitor of colon cancer progresion, but it is required to studied more in order to find the role of this virus on CRC.
Asymmetric GARCH type models for asymmetric volatility characteristics analysis and wind power forecasting
Authors: Chen Hao , Zhang Jianzhong , Tao Yubo , Tan Fenglei 
Published: December 2019

AbstractWind power forecasting is of great significance to the safety, reliability and stability of power grid. In this study, the GARCH type models are employed to explore the asymmetric features of wind power time series and improved forecasting precision. Benchmark Symmetric Curve (BSC) and Asymmetric Curve Index (ACI) are proposed as new asymmetric volatility analytical tool, and several generalized applications are presented. In the case study, the utility of the GARCH-type models in depicting time-varying volatility of wind power time series is demonstrated with the asymmetry effect, verified by the asymmetric parameter estimation. With benefit of the enhanced News Impact Curve (NIC) analysis, the responses in volatility to the magnitude and the sign of shocks are emphasized. The results are all confirmed to be consistent despite varied model specifications. The case study verifies that the models considering the asymmetric effect of volatility benefit the wind power forecasting performance.
National progress, sustainability and higher goals: the case of Bhutan’s Gross National Happiness
Authors: Thinley Jigmi Y. , Hartz-Karp Janette 
Published: December 2019

Abstract
Background
The context of this study is the predominant global paradigm for measuring national progress, the Gross Domestic Product (GDP), which has resulted in an over-emphasis on production and consumption that in turn, is exhausting the planet’s capacity to sustain life. This study examines the potential for a new paradigm of development that can propel human society in a more meaningful, sustainable direction.

Results
Critiques of the GDP are overviewed, but the key critique is that if sustainability, human survival, is our key goal, then GDP, aiming at boundless material wealth, is driving us in the wrong direction. To drive a new sustainable, more meaningful way of life, we need an overarching paradigm with integrated, localized indicators that are internationally accepted as the measures of each nation’s progress. Bhutan’s Gross National Happiness (GNH) Index exemplifies this. Based on the lived experience of a key GNH instigator, its nine domains are explained: Living standard, Health, Education, Ecological diversity and resilience, Cultural diversity and resilience, Community vitality, Time use, Psychological wellbeing, and Good governance. These have informed and been informed by the Sustainable Development Goals. It is outlined how the GNH Index guides development, allocates resources according to the targets set, measures people’s happiness, and measures progress over time and geography.

Conclusion
The economic paradigm underlying the GDP - that the purpose of life is to become rich - is enabling our unsustainability. To enable future sustainability, we need to reconceptualize our concept of national progress. Moreover, since sustainability is effectively a euphemism for survival, then surely, as intelligent, sensitive beings, shouldn’t we be pursuing a higher, shared goal? For the Bhutanese, this is ‘happiness’ - a paradigm that encompasses the pursuit of meaningful societal progress by balancing the physical with mental, the material with spiritual, within a safe and stable environment, with the purpose of realizing happiness. Though the Bhutanese do not claim to have reached a state of national happiness, Bhutan has maintained happiness as its overriding goal, with the tool’s philosophy, authority and accountability driving this in everyday life.
Four amino acids as serum biomarkers for anti-asthma effects in the ovalbumin-induced asthma mouse model treated with extract of Asparagus cochinchinensis
Authors: Choi Jun Young , Kim So Hyun , Kim Ji Eun , Park Ji Won , Kang Mi Ju , Choi Hyeon Jun , Bae Su Ji , Lee Jae Ho , Jung Young-Suk , Hwang Dae Youn 
Published: December 2019

AbstractThe butanol extract of Asparagus cochinchinensis roots fermented with Weissella cibaria (BAW) effectively prevents inflammation and remodeling of airway in the ovalbumin (OVA)-induced asthma model. To characterize biomarkers that can predict the anti-asthmatic effects induced by BAW treatment, we measured the alteration of endogenous metabolites in the serum of OVA-induced asthma mice after administration of low concentration BAW (BAWLo, 250 mg/kg) and high concentration BAW (BAWHi, 500 mg/kg) using 1H nuclear magnetic resonance (1H-NMR) spectral data. The number of immune cells and serum concentration of IgE as well as thickness of the respiratory epithelium and infiltration of inflammatory cells in the airway significantly recovered in the OVA+BAW treated group as compared to the OVA+Vehicle treated group. In the metabolic profile analysis, the pattern recognition showed completely separate clustering of serum analysis parameters between the OVA+Vehicle and OVA+BAW treated groups. Of the total endogenous metabolites, 19 metabolites were upregulated or downregulated in the OVA+Vehicle treated group as compared to the Control treated group. However, only 4 amino acids (alanine, glycine, methionine and tryptophan) were significantly recovered after BAWLo and BAWHi treatment. This study provides the first results pertaining to metabolic changes in the asthma model mice treated with OVA+BAW. Additionally, these findings show that 4 metabolites can be used as one of biomarkers to predict the anti-asthmatic effects.
MycoNews 2019: editorials, news, reports, awards, personalia, book news, and correspondence
Authors: Hawksworth David L. 
Published: December 2019

AbstractThis first instalment of MycoNews includes: an Editorial “Do we need more governance in taxonomy?”; reports of mycological meetings in Poland (18th Congress of European Mycologists), Iran (4th Iranian Mycological Congress) and Chile (1st Chilean Meeting of Mycology (I Encuentro Chileno de Micología); an award to Lynne Boddy; birthday greetings to Gro Gulden, Marja Härkönen, Gregoire Hennebert, Hannes Hertel, and Junta Sugiyama; tributes to the passing of Francisco Calogne, Stanley J. Hughes, and Jos Wessels; news of four mycological books and one on-line work published in 2019; and a special tribute to Stanley Hughes by Kris Pirozynski.
Application of sparse-layer inversion and harmonic bandwidth extension for a channel system in Southern Alberta, Canada
Authors: Mu Yang , Castagna John , Gil Gabriel 
Published: December 2019

Sparse-layer reflectivity inversion decomposes a seismic trace into a limited number of simple layer responses and their corresponding reflection coefficients for top and base reflections. In contrast to sparse-spike inversion, the applied sparsity constraint is less biased against layer thickness and can thus better resolve thin subtuning layers. Application to a 3D seismic data set in Southern Alberta produces inverted impedances that have better temporal resolution and lateral stability and a less blocky appearance than sparse-spike inversion. Bandwidth extension harmonically extrapolated the frequency spectra of the inverted layers and nearly doubled the usable bandwidth. Although the prospective glauconitic sand tunes at approximately 37 m, bandwidth extension reduced the tuning thickness to 22 m. Bandwidth-extended data indicate a higher correlation with synthetic traces than the original seismic data and reveal features below the original tuning thickness. After bandwidth extension, the channel top and base are more evident on inline and crossline profiles. Lateral facies changes interpreted from the inverted acoustic impedance of the bandwidth-extended data are consistent with observations in wells.
Variability of Competition-Based Caloric Expenditure and Relative Heart Rates in National Collegiate Athletic Association Division I Women's Basketball
Authors: Sanders Gabriel J. , Boos Brian , Rhodes Jessica , Peacock Corey A. , Kollock Roger O. , Scheadler Cory M. 
Published: December 2019

Abstract
Sanders, GJ, Boos, B, Rhodes, J, Peacock, CA, Kollock, RO, and Scheadler, CM. Variability of competition-based caloric expenditure and relative heart rates in National Collegiate Athletic Association Division I women's basketball. J Strength Cond Res 36(1): 162–166, 2022—Basketball athletes frequently engage in high intensities (≥85% HRpeak) throughout competition, and it is unknown how high-intensity play coincides with caloric expenditure and average and peak relative heart rates. The purpose of the study was to assess caloric expenditure throughout 31 games (4- to 10-minute quarters) in National Collegiate Athletic Association Division I women's basketball. A total of 11 female athletes were tested for peak heart rate (HRpeak) and peak oxygen uptake (V̇o
2peak) before the season, then monitored in-season with heart rate–based wearable devices. Estimated caloric expenditure, average (% HRavg) and peak (% HRpeak) relative heart rates, time played at intensities ≥85% HRpeak, and live time (i.e., game minutes not including stoppages in play) were recorded each game. Data were assessed as a team and compared across 4 quarters, and then, interathlete comparisons were made based on full game data. There were significant main effects of 10-minute quarters on calories (p < 0.001) and % HRavg (p = 0.015) but not playing intensity ≥85% HRpeak (p = 0.125) and % HRpeak (p = 0.629). Caloric expenditure was the only variable to increase from the first to the fourth quarter. There were main effects of individual athletes on calories, % HRavg, % HRpeak, live time, and playing intensity ≥85% HRpeak (p < 0.001 for all). Assessing individual athletes, relative to a team assessment across quarters, can provide practitioners with more accurate caloric expenditure, heart rate, and playing intensity data per athlete to improve training and fueling protocols.
Evaluating the Burstlet Theory of Inspiratory Rhythm and Pattern Generation
Authors: Kallurkar Prajkta S. , Grover Cameron , Picardo Maria Cristina D. , Del Negro Christopher A. 
Published: December 2019

AbstractThe preBötzinger complex (preBötC) generates the rhythm and rudimentary motor pattern for inspiratory breathing movements. Here, we test “burstlet” theory (Kam et al., 2013a), which posits that low amplitude burstlets, subthreshold from the standpoint of inspiratory bursts, reflect the fundamental oscillator of the preBötC. In turn, a discrete suprathreshold process transforms burstlets into full amplitude inspiratory bursts that drive motor output, measurable via hypoglossal nerve (XII) dischargein vitro. We recap observations by Kam and Feldman in neonatal mouse slice preparations: field recordings from preBötC demonstrate bursts and concurrent XII motor output intermingled with lower amplitude burstlets that do not produce XII motor output. Manipulations of excitability affect the relative prevalence of bursts and burstlets and modulate their frequency. Whole-cell and photonic recordings of preBötC neurons suggest that burstlets involve inconstant subsets of rhythmogenic interneurons. We conclude that discrete rhythm- and pattern-generating mechanisms coexist in the preBötC and that burstlets reflect its fundamental rhythmogenic nature.
Lip-Reading Enables the Brain to Synthesize Auditory Features of Unknown Silent Speech
Authors: Bourguignon Mathieu , Baart Martijn , Kapnoula Efthymia C. , Molinaro Nicola 
Published: December 2019

Lip-reading is crucial for understanding speech in challenging conditions. But how the brain extracts meaning from, silent, visual speech is still under debate. Lip-reading in silence activates the auditory cortices, but it is not known whether such activation reflects immediate synthesis of the corresponding auditory stimulus or imagery of unrelated sounds. To disentangle these possibilities, we used magnetoencephalography to evaluate how cortical activity in 28 healthy adult humans (17 females) entrained to the auditory speech envelope and lip movements (mouth opening) when listening to a spoken story without visual input (audio-only), and when seeing a silent video of a speaker articulating another story (video-only). In video-only, auditory cortical activity entrained to the absent auditory signal at frequencies <1 Hz more than to the seen lip movements. This entrainment process was characterized by an auditory-speech-to-brain delay of ∼70 ms in the left hemisphere, compared with ∼20 ms in audio-only. Entrainment to mouth opening was found in the right angular gyrus at <1 Hz, and in early visual cortices at 1–8 Hz. These findings demonstrate that the brain can use a silent lip-read signal to synthesize a coarse-grained auditory speech representation in early auditory cortices. Our data indicate the following underlying oscillatory mechanism: seeing lip movements first modulates neuronal activity in early visual cortices at frequencies that match articulatory lip movements; the right angular gyrus then extracts slower features of lip movements, mapping them onto the corresponding speech sound features; this information is fed to auditory cortices, most likely facilitating speech parsing.SIGNIFICANCE STATEMENTLip-reading consists in decoding speech based on visual information derived from observation of a speaker's articulatory facial gestures. Lip-reading is known to improve auditory speech understanding, especially when speech is degraded. Interestingly, lip-reading in silence still activates the auditory cortices, even when participants do not know what the absent auditory signal should be. However, it was uncertain what such activation reflected. Here, using magnetoencephalographic recordings, we demonstrate that it reflects fast synthesis of the auditory stimulus rather than mental imagery of unrelated, speech or non-speech, sounds. Our results also shed light on the oscillatory dynamics underlying lip-reading.
Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms
Authors: Sadler Rebecca , Cramer Julia V. , Heindl Steffanie , Kostidis Sarantos , Betz Dene , Zuurbier Kielen R. , Northoff Bernd H. , Heijink Marieke , Goldberg Mark P. , Plautz Erik J. , Roth Stefan , Malik Rainer , Dichgans Martin , Holdt Lesca M. , Benakis Corinne , Giera Martin , Stowe Ann M. , Liesz Arthur 
Published: December 2019

Recovery after stroke is a multicellular process encompassing neurons, resident immune cells, and brain-invading cells. Stroke alters the gut microbiome, which in turn has considerable impact on stroke outcome. However, the mechanisms underlying gut–brain interaction and implications for long-term recovery are largely elusive. Here, we tested the hypothesis that short-chain fatty acids (SCFAs), key bioactive microbial metabolites, are the missing link along the gut–brain axis and might be able to modulate recovery after experimental stroke. SCFA supplementation in the drinking water of male mice significantly improved recovery of affected limb motor function. Usingin vivowide-field calcium imaging, we observed that SCFAs induced altered contralesional cortex connectivity. This was associated with SCFA-dependent changes in spine and synapse densities. RNA sequencing of the forebrain cortex indicated a potential involvement of microglial cells in contributing to the structural and functional remodeling. Further analyses confirmed a substantial impact of SCFAs on microglial activation, which depended on the recruitment of T cells to the infarcted brain. Our findings identified that microbiota-derived SCFAs modulate poststroke recovery via effects on systemic and brain resident immune cells.SIGNIFICANCE STATEMENTPrevious studies have shown a bidirectional communication along the gut–brain axis after stroke. Stroke alters the gut microbiota composition, and in turn, microbiota dysbiosis has a substantial impact on stroke outcome by modulating the immune response. However, until now, the mediators derived from the gut microbiome affecting the gut-immune-brain axis and the molecular mechanisms involved in this process were unknown. Here, we demonstrate that short-chain fatty acids, fermentation products of the gut microbiome, are potent and proregenerative modulators of poststroke neuronal plasticity at various structural levels. We identified that this effect was mediated via circulating lymphocytes on microglial activation. These results identify short-chain fatty acids as a missing link along the gut–brain axis and as a potential therapeutic to improve recovery after stroke.
Monomeric cohesin state revealed by live‐cell single‐molecule spectroscopy
Authors: Liu Wenjie , Biton Elisheva , Pathania Anjali , Matityahu Avi , Irudayaraj Joseph , Onn Itay 
Published: December 2019

AbstractThe cohesin complex plays an important role in the maintenance of genome stability. Cohesin is composed of four core subunits and a set of regulatory subunits that interact with the core subunits. Less is known about cohesin dynamics in live cells and on the contribution of individual subunits to the overall complex. Understanding the tethering mechanism of cohesin is still a challenge, especially because the proposed mechanisms are still not conclusive. Models proposed to describe tethering depend on either the monomeric cohesin ring or a cohesin dimer. Here, we investigate the role of cohesin dynamics and stoichiometry in live yeast cells at single‐molecule resolution. We explore the effect of regulatory subunit deletion on cohesin mobility and found that depletion of different regulatory subunits has opposing effects. Finally, we show that cohesin exists mostly as a canonical monomer throughout the cell cycle, and its monomeric form is independent of its regulatory factors. Our results demonstrate that single‐molecule tools have the potential to provide new insights into the cohesin mechanism of action in live cells.