bluuebunny/crossref_metadata_2025_split huggingface dataset:
Critical success factors for food tourism destinations: A socio‐cultural perspective
Authors: Hiamey Stephen E. , Amenumey Edem K. , Mensah Ishmael 
Published: August 2020

AbstractEating the food of other cultures is fraught with many problems underpinned by many factors chief among them being sociocultural background. The study, therefore, through a socio‐cultural perspective, examines the factors necessary for food tourism development and promotion from tourists' perspectives. Using the tenets of grounded theory, 40 international tourists were interviewed at Cape Coast, Ghana. It was found that sensory characteristics and mediated by factors such as cultural/worldviews influence local food consumption. The findings support the position that the socio‐cultural background of tourists affects their evaluation of a destination's food, hence consumption. Implications of the study are also drawn.
The fifth shade of green: A novel approach to phytoplankton color index assessment in an oligotrophic system
Authors: Abualhaija Rana , Abualhaija Yousef , Tsolaki Eleni , Jimenez Carlos , Lange Manfred A. 
Published: August 2020

AbstractMeasurements of phytoplankton color index (PCI), an indicator of phytoplankton biomass, represent one of the largest datasets acquired through the continuous plankton recorder (CPR) survey. PCI has been used to describe changes in the spatial and temporal distribution of phytoplankton, especially in the North Atlantic, where the methodology was developed and primarily applied. The method functions by grouping samples, based on their color shade, into four categories. Each category is assigned a numerical value to aid spatial and temporal averaging. Recently a CPR has been operated in the Eastern Mediterranean, one of the most oligotrophic areas of the global oceans. To capture the specific characteristics of the area, an additional greenness grading is introduced. In this study, we use satellite‐derived chlorophyll a (Chl a) data to examine whether PCI categories can be distinguished within the low and narrow range of Chl a values found in the study area and to calculate the range of Chl a concentrations expressed by each category. Furthermore, a newly calculated numerical system for the general use of PCI in oligotrophic areas and previously calculated PCI numerical value systems utilizing a variety of in situ, laboratory and remote sensing experiments, were tested for their applicability in the area. Present results indicate the feasibility of employing PCI measurements to provide an estimate of Chl a concentration in the Eastern Mediterranean. This provides confidence in the implementation of a new category system for PCI, as well as the use of the new PCI numerical system for the assessment of phytoplankton in oligotrophic waters.
Genotypic and clinical analysis of 49 Chinese children with hepatic glycogen storage diseases
Authors: Liang Yan , Du Caiqi , Wei Hong , Zhang Cai , Zhang Min , Hu Minghui , Fang Feng , Luo Xiaoping 
Published: August 2020

AbstractBackgroundGlycogen storage disease (GSD) is a relatively rare inborn metabolic disorder, our study aims to investigate the genotypic and clinical feature of hepatic GSDs in China.MethodsThe clinical and genotypic data of 49 patients with hepatic GSDs were collected retrospectively and analyzed.ResultsAfter gene sequencing, 49 patients were diagnosed as GSDs, including GSD Ia (24 cases), GSD IIIa (11 cases), GSD IXa (8 cases), GSD VI (3 cases) and GSD Ib (3 cases). About 45 gene variants of G6PC, AGL, PHKA2, PYGL, and SLC37A4 were detected; among which, 22 variants were unreported previously. c.648G>T (p. Leu216Leu) of G6PC exon 5 is the most common variant for GSD Ia patients (20/24,83.33%）, splice variant c.1735+1G>T of AGL exon 13 is relatively common among GSD IIIa, while novel variant accounts for the majority of GSD IXa and GSD VI patients. As for clinical features, there was no significant difference in the onset age among group GSD Ia, GSD IIIa, and GSD IXa, but the age at diagnosis and average disease duration from diagnosis of GSD Ia were significantly higher than GSD IIIa and GSD IXa. Body weight of GSD patients was basically normal, but growth retardation was relatively common among them, especially for GSD Ia patients; and renomegaly was only found in GSD Ia. Besides, serum cholesterol, triglyceride, lactic acid, and uric acid in GSD Ia were significantly higher than those with GSD IIIa and IXa (p < 0.05); but ALT, AST, CK, and LDH of GSD III and GSD IXa were significantly higher when compared to GSD Ia (p < 0.05).ConclusionsAll hepatic GSDs patients share similarity in clinical and biochemical spectrum, but delayed diagnosis and biochemical metabolic abnormalities were common in GSD Ia. For family with GSD proband, pedigree analysis and genetic testing is strongly recommended.
Polarization insensitive penta‐bandstop frequency selective surface for closely placed bands
Authors: Farooq Umer , Iftikhar Adnan , Shafique Muhammad Farhan , Mughal Muhammad Junaid , Fida Adnan , Khalid Sohail 
Published: August 2020

AbstractThis article reports on a single layer penta‐bandstop frequency selective surface (FSS) for multiband shielding applications. The proposed unit cell incorporates five independent resonant elements that are realized on a single‐sided FR4 substrate to suppress GSM ‐ 0.9 GHz, GPS ‐ 1.5 GHz, GSM ‐ 1.8 GHz, Wi‐Max ‐ 3.5 GHz, and Wireless Local Area Network (WLAN) ‐ 5.7 GHz frequency bands. The proposed single layer unit cell has compact lattice periodicity of order 0.11 λo × 0.11 λo. The design is not only polarization‐insensitive, but it also offers high angular stability up to 45°. A detailed parametric analysis is conducted to establish a relationship between geometrical parameters and FSS spectral response. Additionally, an equivalent lumped circuit model is also derived to further elaborate on the underlying resonance mechanism. A prototype is fabricated and tested to validate the performance of the proposed FSS. The measured results are in good agreement with simulated ones. The proposed FSS has the uniqueness of suppressing 0.9 GHz GSM band that has never been reported in a pentaband design. The proposed FSS is a potential candidate for radio frequency (RF) shielding, electromagnetic wave suppression, and data security applications in secure installations.
DICOM re‐encoding of volumetrically annotated Lung Imaging Database Consortium (LIDC) nodules
Authors: Fedorov Andrey , Hancock Matthew , Clunie David , Brochhausen Mathias , Bona Jonathan , Kirby Justin , Freymann John , Pieper Steve , J. W. L. Aerts Hugo , Kikinis Ron , Prior Fred 
Published: August 2020

PurposeThe dataset contains annotations for lung nodules collected by the Lung Imaging Data Consortium and Image Database Resource Initiative (LIDC) stored as standard DICOM objects. The annotations accompany a collection of computed tomography (CT) scans for over 1000 subjects annotated by multiple expert readers, and correspond to “nodules ≥ 3 mm”, defined as any lesion considered to be a nodule with greatest in‐plane dimension in the range 3–30 mm regardless of presumed histology. The present dataset aims to simplify reuse of the data with the readily available tools, and is targeted towards researchers interested in the analysis of lung CT images.Acquisition and validation methodsOpen source tools were utilized to parse the project‐specific XML representation of LIDC‐IDRI annotations and save the result as standard DICOM objects. Validation procedures focused on establishing compliance of the resulting objects with the standard, consistency of the data between the DICOM and project‐specific representation, and evaluating interoperability with the existing tools.Data format and usage notesThe dataset utilizes DICOM Segmentation objects for storing annotations of the lung nodules, and DICOM Structured Reporting objects for communicating qualitative evaluations (nine attributes) and quantitative measurements (three attributes) associated with the nodules. The total of 875 subjects contain 6859 nodule annotations. Clustering of the neighboring annotations resulted in 2651 distinct nodules. The data are available in TCIA at https://doi.org/10.7937/TCIA.2018.h7umfurq.Potential applicationsThe standardized dataset maintains the content of the original contribution of the LIDC‐IDRI consortium, and should be helpful in developing automated tools for characterization of lung lesions and image phenotyping. In addition to those properties, the representation of the present dataset makes it more FAIR (Findable, Accessible, Interoperable, Reusable) for the research community, and enables its integration with other standardized data collections.
A 32‐channel receive array coil for bilateral breast imaging and spectroscopy at 7T
Authors: Del Bosque Romina , Cui Jiaming , Ogier Stephen , Cheshkov Sergey , Dimitrov Ivan E. , Malloy Craig , Wright Steven M. , McDougall Mary 
Published: August 2020

PurposeThis work describes the construction and evaluation of a bilateral 32‐channel receive array for breast imaging at 7T.MethodsThe receive array consisted of 32 receive coils, placed on two 3D‐printed hemispherical formers. Each side of the receive array consisted of 16 receive loops, each loop having a corresponding detachable board with match/tune capacitors, active detuning circuitry, and a balun. Coil performance was evaluated on homogeneous canola oil phantoms using a Philips Achieva 7T system. Array coil performance was compared with a bilateral forced current excitation volume coil in transmit/receive mode and with a previously reported 16‐channel unilateral coil with a similar design.ResultsThe 32‐channel array had an increase in average SNR throughout both phantoms by a factor of five as compared with the volume coil, with SNR increases up to 10 times along the periphery and three times in the center. Noise measurements showed low interelement noise correlation (average: 5.4%; maximum: 16.8%). Geometry factor maps were acquired for various acceleration factors and showed mean geometry factors <1.2, for combined acceleration factors of up to six.ConclusionsThe improvements achieved demonstrate the clear potential for use in dynamic contrast‐enhanced or diffusion‐weighted MR studies, while maintaining diagnostically relevant spatial and temporal resolutions.
Using Genetic Data to Estimate Capture Rate of Wisconsin and Leech Lake Strains of Muskellunge Stocked in Four Wisconsin Lakes
Authors: Larson Wesley A. , Hill Thompson , Rowe David , Oele Daniel , Gerbyshak Joseph , Bergman Jennifer 
Published: August 2020

Abstract
Many inland fisheries are supported by stocking hatchery-produced fish, and fisheries managers often face difficult decisions regarding strain selection. Stocking evaluations that are designed to quantify differences in strain performance provide valuable data for designing stocking programs. Here, we used genetic tools to investigate the capture rate of two strains of Muskellunge that were stocked in Wisconsin lakes. We genotyped a total of 1,011 Muskellunge at 13 microsatellites and used the data from five reference populations to assign fish that were stocked in four Wisconsin lakes to their strain of origin. The strains that were stocked in these lakes were derived from Wisconsin populations in the upper Chippewa River and Wisconsin River drainages and from Leech Lake, Minnesota. The Muskellunge from Leech Lake demonstrated much lower capture rates than the Wisconsin strain, but the results were variable, with a 10% capture rate of fish from the Leech Lake strain in Lake Monona and a 2% capture rate in Lake Wissota, despite similar stocking rates (~25%) in both lakes. We hypothesized that the higher capture rates of Muskellunge from the Wisconsin strain could be due the adaptative advantages of the Wisconsin strain in these waters and suggest that managers continue to stock the nearest native (i.e., Wisconsin) strain to achieve the highest return on investment.
New strategies for determining backward perturbation bound of approximate two‐sided Krylov subspaces
Authors: Wang Yunjie , Wu Gang 
Published: August 2020

SummaryGiven a nonsymmetric matrix and two unit norm vectors, the two‐sided Krylov subspace methods construct a pair of bases for two Krylov subspaces with respect to A and AT, respectively. In practical calculations, however, the two subspaces spanned by the computed bases may not be Krylov subspaces. Given two subspaces and , in [G. Wu et al, Toward backward perturbation bounds for approximate dual Krylov subspaces, BIT, 53 (2013), pp. 225‐239], the authors considered how to determine a backward perturbation E whose norm is as small as possible, such that and are Krylov subspaces of A + E and (A + E)T, respectively. However, as the two bases used are biorthonormal, their results are nonoptimal in terms of unitarily invariant norms, and the perturbation bound can be greatly overestimated. In this work, we revisit this problem and use orthonormal bases instead of biorthonormal bases to derive new perturbation bounds. We propose two new strategies, the first one focuses on choosing optimal orthonormal basis matrices, and the second one resorts to solving small‐sized generalized Sylvester matrix equations. Numerical experiments show that our bounds improve the existing one substantially.
Outcomes in children with hemophilia A with inhibitors: Results from a noninterventional study
Authors: Oldenburg Johannes , Shima Midori , Kruse‐Jarres Rebecca , Santagostino Elena , Mahlangu Johnny , Lehle Michaela , Selak Bienz Nives , Chebon Sammy , Asikanius Elina , Trask Peter , Mancuso Maria Elisa , Jiménez‐Yuste Victor , von Mackensen Sylvia , Levy Gallia G. 
Published: August 2020

AbstractBackgroundData regarding management of pediatric persons with hemophilia A (PwHA) with factor VIII (FVIII) inhibitors are limited. This prospective noninterventional study (NCT02476942) evaluated annualized bleeding rates (ABRs), safety, and health‐related quality of life (HRQoL) in pediatric PwHA with FVIII inhibitors.ProcedurePwHA aged <12 years with current FVIII inhibitors and high‐titer inhibitor history were enrolled. Participants remained on usual treatment; no interventions were applied. Outcomes included ABR, safety, and HRQoL.ResultsTwenty‐four PwHA aged 2‐11 years (median 7.5) were enrolled and monitored for 8.7‐44.1 weeks (median 23.4). In the episodic (n = 10) and prophylactic (n = 14) groups, respectively, 121 of 185 (65.4%) and 101 of 186 (54.3%) bleeds were treated using activated prothrombin complex concentrate (aPCC) and/or recombinant activated FVII (rFVIIa). ABRs (95% confidence interval) were 19.4 (13.2‐28.4) and 18.5 (14.2‐24.0) for treated bleeds, and 32.7 (20.5‐52.2) and 33.1 (22.4‐48.9) for all bleeds, respectively. Most prophylactic group participants (92.9%) were prescribed aPCC; 50% adhered to their prescribed treatment regimen. Adherence to prophylactic rFVIIa was not assessed. Serious adverse events included hemarthrosis (12.5%) and mouth hemorrhage (12.5%); the most common nonserious adverse event was viral upper respiratory tract infection (12.5%). HRQoL showed functional impairment at baseline; scores remained stable throughout, with little intergroup variation.ConclusionsABRs remained high in pediatric PwHA with inhibitors receiving standard treatment. This study demonstrates the need for more effective treatments, with reduced treatment burden, to prevent bleeds, increase prophylaxis adherence, and improve patient outcomes.
Tissue ionome response to rhizosphere pH and aluminum in tea plants (Camellia sinensis L.), a species adapted to acidic soils
Authors: Yamashita Hiroto , Fukuda Yusuke , Yonezawa Shiori , Morita Akio , Ikka Takashi 
Published: August 2020

AbstractThe growth of tea plants (Camellia sinensis L.) is promoted by the presence of aluminum (Al), a beneficial element under acidic conditions, but the influence of rhizosphere pH on this interaction is not known. To understand the mechanisms underlying the adaptation to acidic rhizosphere conditions, we evaluated ionome profiles and the effect of pH on tea growth in hydroponic culture. The optimum pH for tea growth was around pH 4.2, and growth was inferior under a pH less than 3.8 or higher than 5.0. Under the optimum pH growth and Al accumulation were markedly stimulated by Al treatment. Al content and accumulation in new and mature leaves and new roots (the predominant tissues that accumulate minerals in tea plants) gradually declined with decrease in pH, especially in new roots. Ionome profiles drastically altered Al treatment, but changes were more pronounced in new roots than in new or mature leaves and did not depend on pH. Although the uptake of most cationic minerals in new roots was decreased by Al treatment, cationic mineral contents in new and mature leaves were not decreased by Al. In contrast to other plant species, the content and accumulation of manganese, despite it being a cationic nutrient, were significantly increased by Al treatment. These results indicated that one role of Al as a beneficial element was to maintain the shoot nutrient status by effectively utilizing Al‐limited elements in the roots.
Reduction‐sensitive carrier containing disulfide bond based on Pluronic F68 with cholesterol for drug delivery
Authors: Zhang Yichen , Fan Xiaoshan , Yu Yongjie , Li Wenqiang , Huang Hongpan , Zhang Weiwei , Hu Zhiguo , Li Zibiao 
Published: August 2020

AbstractThe reduction‐sensitive amphiphilic polymer chol‐SS‐F68‐SS‐Chol (F68‐CDEC. chol, SS and F68 represent cholesterol, disulfide bond and Pluronic F68, respectively) was easily synthesized by two steps of esterification reactions. The self‐assembly behavior of the polymer was studied by fluorescence spectrophotometry, dynamic light scattering and TEM. Impressively, the critical micelle concentration of F68‐CDEC was 58‐fold smaller than that of F68. Besides, the drug loading content (LC = 20.25%) was higher than that of F68 (LC = 13.42%). In vitro release experiments showed that the reductant dithiothreitol triggered rapid disintegration of micelles with an accumulated drug amount of 55%, compared with an accumulated drug amount of 20% in phosphate‐buffered saline solution. These good abilities were further proved by cell uptake experiments. More importantly, almost no cytotoxicity was observed by 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide (MTT) colorimetric assay and immunofluorescence staining experiments. There are reasons to believe that the polymer F68‐CDEC can be used as a reduction‐sensitive drug delivery material. © 2020 Society of Industrial Chemistry
Progressive task‐oriented circuit training for cognition, physical functioning and societal participation in individuals with dementia
Authors: Gbiri Caleb Ademola Omuwa , Amusa Biliafeez Francisca 
Published: August 2020

AbstractBackground and objectivesDementia is commonly associated with cognitive deficit, functional decline and societal participation restriction across multiple domains of functioning. The decline impacts not only on the individual, but also on their informal caregivers, healthcare and the social system. This clinical random controlled study investigated the efficacy of 12‐week Progressive Task‐oriented circuit training on cognition, physical functioning and societal participation of individuals with dementia.MethodsThis study involved 31 individuals living with dementia recruited from a tertiary health institution in Lagos Nigeria. They were randomized into two groups: Progressive Task‐oriented circuit training (involved in 12‐week circuit training, two times a week for 70 min per session consisting of six workstations) and Control group (training with conventional treatment and home programmes). They were assessed at baseline, mid‐intervention and post‐intervention using Mini‐Mental State Examination (MMSE), Alzheimer's Disease Assessment Scale‐Cognition (ADAS‐Cog), Bristol ADLs, Community integration Questionnaire, 6‐min walk test. Data analysed using the independent‐samples t tests, paired t tests, Friedman two‐way analysis of variance and Mann–Whitney U test (p ≤ .05).ResultsParticipants were aged 69.61 ± 3.44 years. There was significant improvement from baseline to post‐intervention in cognition (30.77 ± 1.02 vs. 28.77 ± 3.30), physical functioning (28.19 ± 3.90 vs. 25.84 ± 6.26) and societal participation (3.64 ± 0.73 vs. 5.59 ± 2.76). However, the progressive Task‐oriented circuit training had more significant improvement than the control group within the group in cognition (p = .000), physical functioning (p = .000), and societal participation (p = .000). There was no statistical difference within the Control group with cognition (p = .097), Physical functioning (p = 1.000). Meanwhile there was statistically significant effect between both groups on cognition, physical functioning and societal participation post‐intervention (p < .005).ConclusionAlthough both Task‐oriented Circuit Training and conventional treatment with home exercise programmes are efficacious, Progressive Task‐oriented Circuit Training is more efficacious in enhancing and developing therapeutic strategies to train cognition, improve functional performance and societal participation in the rehabilitation of individuals with dementia.
Do patients with low back pain remember physiotherapists' advice? A mixed‐methods study on patient‐therapist communication
Authors: Supp Georg , Schoch Wolfgang , Baumstark Manfred W. , May Stephen 
Published: August 2020

AbstractObjectivesThe primary aim of this study was to determine if the advice physiotherapists think they provide to patients with low back pain (LBP) is what the patients remember and take away from the clinical encounter. The secondary aim was to determine which factors may influence the retention of this advice.MethodsThe first component of the study used questionnaires completed by patients and therapists after the initial visit. Related questionnaires of patients and therapists were screened for inconsistencies. The second component of the study involved semi‐structured interviews.ResultsNinety pairs of questionnaires were completed. Therapists provided patients with one (N = 90), two (N = 85) or three (N = 51) items of advice regarding the management of their LBP. All patients remembered the first item of advice, 92% remembered a second, and 67% remembered the third piece of advice. All items of advice were deemed either ‘relevant’ or ‘very relevant’ by 97% of the patients. After the analysis of 14 interviews, data saturation was reached. Four themes emerged from the data analysis of the interviews: (a) Evaluation type, (b) Exercise factors, (c) Patient concerns about their diagnosis, and (d) Patient expectations.DiscussionIn most cases, patients remembered what therapists told them and considered that the advice provided was relevant. Based on the qualitative data, patients were more likely to remember what therapists said when: (a) shared decision making was used during the initial encounter, (b) prescribed exercises were simple to perform and few in number, (c) patients' concerns about their diagnosis were addressed, and (d) patients' expectations were identified and addressed.