bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disintegration characteristics in granite residual soil and their relationship with the collapsing gully in South China
Authors: Li Chengsheng , Kong Lingwei , Shu Rongjun , An Ran , Zhang Xianwei 
Published: November 2020

Abstract
The climate is a significant factor affecting the collapsing gully in weathered granite areas, and most of the surface layers of the collapsed area comprise granite residual soil. Granite residual soil has complex disintegration characteristics under different initial water content conditions. Besides, its disintegration characteristic is an essential factor for collapsing gully. Therefore, disintegration tests, triaxial shear tests, nuclear magnetic resonance tests, and hydraulic conductivity tests are conducted under torridity and rainstorm conditions in order to study the disintegration characteristics of granite residual soil. The results of disintegration test showed that the initial disintegration rate of granite residual soil increased rapidly with the decrease in water content, while the relationship between disintegration rate and water content in the later stage of disintegration is unclear. When soaked, the maximum decrease in cohesion was 44.48%, the hydraulic conductivity became six times larger, and the amplitude of the T
2 curve increased by about 40%, which reduced the strength of the soil and provided better access for rainwater infiltration to deeper stratum. The results show that the microstructure of granite residual soil would be damaged and the disintegration would occur after a rainstorm at low water content. Micropores would be formed inside the sample after soaking, resulting in destroying the continuity of the material.
Importance of traditional landscapes in Slovenia for conservation of endangered butterfly
Authors: Zupan Sara , Bužan Elena , Grubar Valentina Brečko , Jugovic Jure 
Published: November 2020

Abstract
Maintenance of traditional cultural landscapes largely depends on traditional agricultural practices, which are nowadays in decline as a result of increasingly intensive and mechanised land use. Losing traditional practices may result in impoverishing of picturesque mosaic landscape and biodiversity. This research focuses on land-use changes in two time periods (2002–2008; 2013–2016) and effects of changes reflecting on populations of critically endangered butterfly. False Ringlet, Coenonympha oedippus (Lepidoptera: Nymphalidae), is a habitat specialist, which in Slovenia inhabits two geographically distinct contrasting habitats – dry meadows in south-western and wetlands in central Slovenia. We compared nine environmental parameters to assess environmental differences, which shape species habitat; seven parameters significantly differ among the four geographical regions and five among the two habitat types. Four parameters significantly differ (i.e. at least in two regions) when tested for homogeneity, while in dry habitat type all (except slope) were significant and none in wet habitat. Changes in land use in two studied periods lit up two processes: transformation of meadows into agricultural land and overgrowing of the meadows, both processes affecting species severely. We believe that maintaining of traditional landscapes in future could serve as a good conservation practice for this endangered species.
Effect of photogrammetric RPAS flight parameters on plani-altimetric accuracy of DTM
Authors: Mora-Felix Zuriel Dathan , Sanhouse-Garcia Antonio Jesus , Bustos-Terrones Yaneth A. , Loaiza Juan G. , Monjardin-Armenta Sergio Alberto , Rangel-Peraza Jesus Gabriel 
Published: November 2020

AbstractRemotely piloted aerial systems (RPASs) are gaining fast and wide application around the world due to its relative low-cost advantage in the acquisition of high-resolution imagery. However, standardized protocols for the construction of cartographic products are needed. The aim of this paper is to optimize the generation of digital terrain models (DTMs) by using different RPAS flight parameters. An orthogonal design L18 was used to measure the effect of photogrammetric flight parameters on the DTM generated. The image data were acquired using a DJI Phantom 4 Pro drone and six flight parameters were evaluated: flight mode, altitude, flight speed, camera tilt, longitudinal overlap and transversal overlap. Fifty-one ground control points were established using a global positioning system. Multivision algorithms were used to obtain ultra-high resolution point clouds, orthophotos and 3D models from the photos acquired. Root mean square error was used to measure the geometric accuracy of DTMs generated. The effect of photogrammetric flight parameters was carried out by using analysis of variance statistical analysis. Altimetric and planimetric accuracies of 0.38 and 0.11 m were achieved, respectively. Based on these results, high-precision cartographic material was generated using low-cost technology.
Orienting Attention to Short-Term Memory Representations via Sensory Modality and Semantic Category Retro-Cues
Authors: Backer Kristina C. , Buchsbaum Bradley R. , Alain Claude 
Published: November 2020

AbstractThere is growing interest in characterizing the neural mechanisms underlying the interactions between attention and memory. Current theories posit that reflective attention to memory representations generally involves a fronto-parietal attentional control network. The present study aimed to test this idea by manipulating how a particular short-term memory (STM) representation is accessed, that is, based on its input sensory modality or semantic category, during functional magnetic resonance imaging (fMRI). Human participants performed a novel variant of the retro-cue paradigm, in which they were presented with both auditory and visual non-verbal stimuli followed by Modality, Semantic, or Uninformative retro-cues. Modality and, to a lesser extent, Semantic retro-cues facilitated response time relative to Uninformative retro-cues. The univariate and multivariate pattern analyses (MVPAs) of fMRI time-series revealed three key findings. First, the posterior parietal cortex (PPC), including portions of the intraparietal sulcus (IPS) and ventral angular gyrus (AG), had activation patterns that spatially overlapped for both modality-based and semantic-based reflective attention. Second, considering both the univariate and multivariate analyses, Semantic retro-cues were associated with a left-lateralized fronto-parietal network. Finally, the experimental design enabled us to examine how dividing attention cross-modally within STM modulates the brain regions involved in reflective attention. This analysis revealed that univariate activation within bilateral portions of the PPC increased when participants simultaneously attended both auditory and visual memory representations. Therefore, prefrontal and parietal regions are flexibly recruited during reflective attention, depending on the representational feature used to selectively access STM representations.
Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission
Authors: Zarebidaki Fereshteh , Camacho Marcial , Brockmann Marisa M. , Trimbuch Thorsten , Herman Melissa A. , Rosenmund Christian 
Published: November 2020

Efficient neurotransmitter release at the presynaptic terminal requires docking of synaptic vesicles to the active zone membrane and formation of fusion-competent synaptic vesicles near voltage-gated Ca2+channels. Rab3-interacting molecule (RIM) is a critical active zone organizer, as it recruits Ca2+channels and activates synaptic vesicle docking and priming via Munc13-1. However, our knowledge about Munc13-independent contributions of RIM to active zone functions is limited. To identify the functions that are solely mediated by RIM, we used genetic manipulations to control RIM and Munc13-1 activity in cultured hippocampal neurons from mice of either sex and compared synaptic ultrastructure and neurotransmission. We found that RIM modulates synaptic vesicle localization in the proximity of the active zone membrane independent of Munc13-1. In another step, both RIM and Munc13 mediate synaptic vesicle docking and priming. In addition, while the activity of both RIM and Munc13-1 is required for Ca2+-evoked release, RIM uniquely controls neurotransmitter release efficiency. However, activity-dependent augmentation of synaptic vesicle pool size relies exclusively on the action of Munc13s. Based on our results, we extend previous findings and propose a refined model in which RIM and Munc13-1 act in overlapping and independent stages of synaptic vesicle localization and release.SIGNIFICANCE STATEMENTThe presynaptic active zone is composed of scaffolding proteins that functionally interact to localize synaptic vesicles to release sites, ensuring neurotransmission. Our current knowledge of the presynaptic active zone function relies on structure-function analysis, which has provided detailed information on the network of interactions and the impact of active zone proteins. Yet, the hierarchical, redundant, or independent cooperation of each active zone protein to synapse functions is not fully understood. Rab3-interacting molecule and Munc13 are the two key functionally interacting active zone proteins. Here, we dissected the distinct actions of Rab3-interacting molecule and Munc13-1 from both ultrastructural and physiological aspects. Our findings provide a more detailed view of how these two presynaptic proteins orchestrate their functions to achieve synaptic transmission.
Prediction of the Bicarbonate Amount in Drinking Water in the Region of Médéa Using Artificial Neural Network Modelling
Authors: Tahraoui Hichem , Belhadj Abd Elmouneïm , Hamitouche Adhya Eddine 
Published: November 2020

The region of Médéa (Algeria) located in an agricultural site requires a large amount of drinking water. For this purpose, the water analyses in question are imperative. To examine the evolution of the drinking water quality in this region, firstly, an experimental protocol was done in order to obtain a dataset by taking into account several physicochemical parameters. Secondly, the obtained data set was divided into two parts to form the artificial neural network, where 70 % of the data set was used for training, and the remaining 30 % was also divided into two equal parts: one for testing and the other for validation of the model. The intelligent model obtained was evaluated as a function of the correlation coefficient nearest to 1 and lowest mean square error (RMSE). A set of 84 data points were used in this study. Eighteen parameters in the input layer, five neurons in the hidden layer, and one parameter in the output layer were used for the ANN modelling. Levenberg Marquardt learning (LM) algorithm, logarithmic sigmoid, and linear transfer function were used, respectively, for the hidden and the output layers. The results obtained during the present study showed a correlation coefficient of &lt;i&gt;R&lt;/i&gt; = 0.99276 with root mean square error RMSE = 11.52613 mg dm&lt;sup&gt;–3&lt;/sup&gt;. These results show that obtained ANN model gave far better and more significant results. It is obviously more accurate since its relative error is small with a correlation coefficient close to unity. Finally, it can be concluded that obtained model can effectively predict the rate of soluble bicarbonate in drinking water in the Médéa region.
Carpal tunnel syndrome in acromegaly: a nationwide study
Authors: Vouzouneraki Konstantina , Esposito Daniela , Mukka Sebastian , Granfeldt Daniel , Ragnarsson Oskar , Dahlqvist Per , Olsson Daniel S 
Published: November 2020

Objective
Carpal tunnel syndrome (CTS) is common in patients with acromegaly, with a reported prevalence of 19–64%. We studied CTS in a large national cohort of patients with acromegaly and the temporal relationship between the two diagnoses.

Design
Retrospective, nationwide, cohort study including patients diagnosed with acromegaly in Sweden, 2005–2017, identified in the Swedish Healthcare Registries.

Methods
CTS (diagnosis and surgery in specialised healthcare) was analysed from 8.5 years before the diagnosis of acromegaly until death or end of the study. Standardised incidence ratios (SIRs) with 95% CIs were calculated for CTS with the Swedish population as reference.

Results
The analysis included 556 patients with acromegaly (50% women) diagnosed at mean (s.d.) age 50.1 (15.0) years. During the study period, 48 patients were diagnosed with CTS and 41 patients underwent at least one CTS surgery. In the latter group, 35 (85%) were operated for CTS before the acromegaly diagnosis; mean interval (range) 2.2 (0.3–8.5) years and the SIR for having CTS surgery before the diagnosis of acromegaly was 6.6 (4.8–8.9). Women with acromegaly had a higher risk for CTS than men (hazard ratio: 2.5, 95% CI: 1.3–4.7).

Conclusions
Patients with acromegaly had a 6-fold higher incidence for CTS surgery before the diagnosis of acromegaly compared with the general population. The majority of patients with both diagnoses were diagnosed with CTS prior to acromegaly. Increased awareness of signs of acromegaly in patients with CTS might help to shorten the diagnostic delay in acromegaly, especially in women.
Mandelstam and Heraclitus
Authors: Kikhney Liubov 
Published: November 2020

The article proves that the ontological poetics of Osip Mandelstam and one of his sources of the concept of the word lie in the doctrine of the Logos of Heraclitus of Ephesus, which is set in the surviving fragments of his treatise On Nature. The author comments on the explicit and hidden references of Mandelstam to Heraclitus and shows the specifics of the functional refraction of Heraclitic allusions in different periods of the Acmeist poet’s work.It is noted that Mandelstam received from Heraclitus the material-being and sensually perceived the integral and hypostatic idea of the Logos as a kind of cosmic law, and at the same time as an ordinary human word, the form of which can nevertheless conceal an analogy with the laws of the world order.Like Heraclitus, Mandelstam assumes that the universe (cosmos) has different stages of formation, controlled by the Logos. According to Heraclitus, the primary basis of the world, its material root is fire. The idea of the changing state of natural substances, their mutual transitions and transformations caused by the “world fire,” which goes back to Heraclitus, permeates a number of the poet’s works written in the era of social upheavals. In the “post-revolutionary” period, Mandelstam develops the idea of the unity of the world and aeonic time, based on Heraclitus. Heraclitic overtones are discerned in a number of Mandelstam’s poems of the 1920s and 30s, including one of his final works – Poems about the Unknown Soldier.In light of the discovered references, Mandelstam, with the sayings of Heraclitus, clarified a number of aesthetic ideas and tropic moves of the poet – for example, the idea of the correlation of how sound envelops speech and its meaning; the motive is the “fluidity” of the world and at the same time its structural unity; the method of the “reversible metaphor of,” marking the identity or paradoxical union of different and sometimes antinomic phenomena.
Scenery by M. V. Dobuzhinsky as a Version of Pushkin Studies
Authors: Markov Alexander 
Published: November 2020

The sets by M. V. Dobuzhinsky for the operas by Mussorgsky and Tchaikovsky based on Pushkin’s works represent an attempt to reconstruct Pushkin’s world and Pushkin’s attitude to history. The libretto required a stylization and standardization of scenography, but Dobuzhinsky continued to interpret the images of St. Petersburg and central Russia, correlating the plots of operas with a new national upsurge. Thus, the plot of The Queen of Spades was understood as part of Pushkin’s view on the successes and failures of the Petrine reforms, about the connection between adventurism and the imperial style, which corresponded to the general cultural myth of Petersburg but was supplemented by a number of observations on the Pushkin text. The plot of Boris Godunov was read not as a Russian story, but as a common one for countries inheriting the Polish-Lithuanian Commonwealth and Russia. The plot of Eugene Onegin was brought closer to the dacha plots of Russian literature, becoming part of the integrated image of a lost Russia. It is proved that Dobuzhinsky in his decisions followed not the structure of the libretto, but a close reading of Pushkin’s texts.
The School of Reading Osip Mandelshtam: Readers No. 1, 2, 3
Authors: Timenchik Roman 
Published: November 2020

“To prove now, that the history of literature is not only the history of writers, but also the history of readers […] means to belabor the obvious,” stated Alexander Beletskii a century ago, but the task of the detailed detecting of the separate groups, or rather to use Boris Tomashevskii’s term, “schools” of readers, is still vital for the historians of modern Russian poetry. The following is the attempt to name the first “enrollees” of the school of reading Osip Mandelshtam’s poetry, two of them sharing his activities in the literary workshop “The Guild of the Poets” in St. Petersburg in the 1910s, and the third being the poet’s wife during 1919–1938.
To Be or Not to Be (Inpatient Versus Observation): Improving Admission-Status Assignment
Authors: Fulchiero Rosanna , Tilman Laura , Green Simone , Bangiolo Lois , Hanvey Lisa , Ellinger Steve , Shuster Brooke , Port Courtney 
Published: November 2020

BACKGROUND:
Observation care is frequently indistinguishable from inpatient care. However, the financial burden of inappropriate status assignment for hospitals and patients can be large. Increased awareness of the potential for financial hardships experienced by patients because of status designation spurred interest among physicians in this improvement project. The goal was to improve the percentage of appropriate inpatient-status assignments from 76% to 90% in 2 years and eliminate observation assignments for patients with hospitalizations &gt;48 hours.

METHODS:
Our multidisciplinary team used the Model for Improvement. Interventions included securing a lead physician advisor to the use-review team, improving the process for status review and adjustment, and creating educational sessions and tools for physicians. Data collected included the percentage of appropriate inpatient assignments, percentage of observation assignments for patients with hospitalizations &gt;48 hours, write-off dollar amount per year from denial of payment due to payer disagreement with inpatient status, and resident physician confidence in assigning status.

RESULTS:
Appropriate use of inpatient assignments increased from 76% to 84%. Status assignments remaining in observation &gt;48 hours of hospital length of stay decreased by one-half, from 6% to 3%. The write-off dollar amount increased during the study period but decreased by 19% the following calendar year, 2018. Resident self-reported confidence in status designation increased after educational sessions.

CONCLUSIONS:
Careful selection of admission status by educated providers and a system to identify relevant cases for status changes can increase appropriate status assignment and, potentially, positively affect the economic burden placed on patients and hospitals.
Sleep in Hospitalized Children With Cancer: A Cross-Sectional Study
Authors: Traube Chani , Rosenberg Lynne , Thau Francesca , Gerber Linda M. , Mauer Elizabeth A. , Seghini Thomas , Gulati Nitya , Taylor Damani , Silver Gabrielle , Kudchadkar Sapna R. 
Published: November 2020

OBJECTIVES:
Many children with cancer have repeated and prolonged hospitalizations, and in-hospital sleep disruption may negatively affect outcomes. Our objective for this study was to characterize sleep quality and quantity in hospitalized children with cancer by using parental surveys and actigraphy, to evaluate the association between subjective and objective sleep measures, and to describe hospital-associated risk factors related to poor sleep.

METHODS:
Cross-sectional study of children aged 0 to 18 years old admitted to a pediatric oncology ward. Parents completed a baseline sleep questionnaire describing their child’s sleep at home before hospitalization, followed by daily questionnaires describing their child’s sleep for up to 3 nights while in the hospital. A subgroup of children aged 5 to 18 years wore actigraphs during the same time period. Demographic and clinical data were extracted from the electronic medical record. The primary outcome was inadequate sleep, defined by the total sleep duration adjusted for age.

RESULTS:
Among 56 participants over 135 hospital nights, 66% (n = 37) reported inadequate sleep. Actigraphy was completed on 39 nights (29%), with a median total sleep time of 477 (interquartile range 407–557) minutes. There was a strong correlation between subjective questionnaire measures and actigraphic measures (r = 0.76). No patient-specific demographic factors were related to inadequate sleep. A multivariable model indicated the following hospital-related factors were associated with inadequate sleep: noise (adjusted odds ratio [aOR] 3.0; confidence interval [CI] 1.2–7.7), alarms (aOR 3.1; CI 1.2–8.3), child’s worries (aOR 2.8; CI 1.1–7.2), and receipt of benzodiazepines (aOR 2.9; CI 1.2–7.5).

CONCLUSIONS:
A majority of children experienced inadequate sleep during hospitalization. Subjective report of sleep duration correlated well with objective measures of sleep by actigraphy. Several potentially modifiable factors were independently associated with poor sleep. Further interventional studies are required to test approaches to optimize sleep in hospitalized children with cancer.
Associations Between Obesity and Use for Pediatric Hospitalizations
Authors: Kyler Kathryn E. , Hall Matt , Bettenhausen Jessica L. 
Published: November 2020

BACKGROUND:Obesity is associated with poor outcomes for specific clinical groups of hospitalized children, but few data exist on outcomes of children with obesity on a larger scale during hospitalization. Therefore, we aimed to determine if use outcomes differ between hospitalized children with obesity and hospitalized children without obesity.METHODS:We performed a retrospective longitudinal cohort study of all children aged 2 to 19 years hospitalized at a single academic institution between January 1, 2009, and December 31, 2016. BMI was calculated from documented height and weight; obesity was defined by using age- and sex-specific BMI percentile guidelines from the Centers for Disease Control and Prevention. Only All Patient Refined Diagnosis-Related Groups (APR-DRGs) with &gt;100 admissions during the study period were included. Primary outcome measures included hospital length of stay, hospital cost, and 14-day readmission. Generalized linear and logistic models were used to determine adjusted differences for outcome measures between patients with and without obesity.RESULTS:Of 78 756 included hospitalizations, obesity rates increased from 16.5% in 2009–2010 to 17.3% in 2015–2016 (P = .002). Only 6 (4.7%) of the 128 APR-DRGs examined were associated with increased use for patients with obesity: spinal procedures, tonsil and adenoid procedures, major respiratory procedures, peptic ulcer and gastritis, other musculoskeletal diagnoses, and other kidney and urinary tract diagnoses. There were no APR-DRGs with increased length of stay for children with obesity.CONCLUSIONS:Obesity is associated with increased hospitalization cost and readmission rates for a minority of diagnosis groups. Some groups of hospitalized children with obesity may benefit from targeted interventions to reduce obesity-specific risks. Future research should be focused on disparities in other relevant clinical outcomes.