bluuebunny/crossref_metadata_2025_split huggingface dataset:
8. La liturgie impériale et les jeux durant l’Antiquité tardive : entre paganisme et christianisme
Authors: Jiménez Sánchez Juan Antonio 
Published: October 2020

La christianisation des spectacles de la tradition païenne et de la liturgie impériale liée au cirque est un phénomène très complexe et qui offre plusieurs aspects qui peuvent nous sembler paradoxaux, ces manifestations festives étant nées des cultes en l’honneur des dieux païens. Le premier pas dans la christianisation des jeux a été leur sécularisation, accomplie dès la fin du ive siècle. Il faut considérer de surcroît la théologie de la victoire impériale et sa relation de plus en plus importante avec le Dieu chrétien tout au long du ive siècle. En Orient, la liturgie impériale liée à l’hippodrome s’est christianisée dès le milieu du ve siècle, comme on peut le voir dans le Livre des cérémonies. En Occident, on dispose du témoignage de Salvien de Marseille et de l’iconographie de quelques monnaies de Valentinien III.
9. De l’auctoritas senatus à l’Imperator auctor : le Sénat, les généraux vainqueurs et les amis et alliés du peuple romain aux deux derniers siècles de la République
Authors: Sánchez Pierre 
Published: October 2020

Dès le début de l’expansion romaine en Méditerranée au iiie siècle av. J.-C., l’État romain a pris conscience de la nécessité de protéger les sujets, amis et alliés de Rome contre les abus commis par ses propres ressortissants : généraux et soldats, gouverneurs de province, publicains et negotiatores. À partir des années 170 av. J.-C., on voit apparaître des sénatus-consultes et des lois de portée générale, visant à défendre l’auctoritas du Sénat dans la gestion de la politique extérieure et à réguler les activités des généraux et gouverneurs. Dans le même temps, quelques imperatores ambitieux se sont présentés aux alliés comme les véritables garants (auctores) des mesures prises en faveur des alliés. C’est ce qu’illustrent plusieurs lettres et décrets émanant de Flamininus, des Scipion, de Lucullus, de César ou d’Octavien, qui tous annoncent le discours tenu par les empereurs.
17. Theodosiani liber quintus dans l’édition de Théodore Mommsen : quelques observations
Authors: Jaillette Pierre 
Published: October 2020

Au début des années 1820 on découvrit, à la bibliothèque royale de Turin, dans un manuscrit palimpseste jusque-là délaissé en raison de son état lamentable – le Taurinensis a. II, 2 –, de nouveaux fragments du Code Théodosien qui, joints à ceux trouvés à Milan, rendaient obsolète l’édition de J.-L. Beck, parue à Berlin en 1815. Les études menées sur ces textes permirent à G. Haenel de procurer, en 1842, une nouvelle édition de la compilation promulguée en 438 par l’empereur d’Orient Théodose II. Considérée comme médiocre, elle ne sera cependant remplacée qu’en 1904-1905 par celle de Th. Mommsen. Celui-ci tira grandement profit des recherches menées par son collègue Paul Krueger : c’est d’ailleurs à ce dernier qu’aurait dû revenir l’honneur de la publication, en raison notamment de la pertinence des recherches qu’il avait menées sur le manuscrit de Turin et des réflexions qu’il avait longuement mûries sur la structure du Livre V, pour lequel on se propose de montrer ici, à partir de quelques exemples, combien certains des choix éditoriaux de Mommsen apparaissent discutables.
La recherche française récente sur Versailles et la cour. Problématiques et orientations
Authors: Sabatier Gérard 
Published: October 2020

Durant les trente dernières années, la recherche française sur Versailles et la cour a ouvert une nouvelle époque dans la connaissance de l’ingénierie de la monarchie bourbonienne en France. Le Versailles royal était devenu, au xixe siècle, un musée de l’histoire de France par l’opération de Louis-Philippe, tandis que l’histoire de la cour relevait du romanesque. La résurrection du Versailles royal commença la première avec les conservateurs du château. La genèse des bâtiments, l’étude, l’inventaire, la restauration des mobiliers, des décors peints, de la sculpture, des jardins, l’archéologie des ensembles disparus (Marly…) ont mobilisé les historiens d’art, les corps de métier spécialisés, les importantes dotations de l’État et des mécènes. La promotion de la cour comme objet d’histoire est plus récente. L’impulsion est venue des sociologues, des anthropologues ; les historiens ont suivi, dans un contexte largement européen. Le Centre de recherche du château de Versailles, fondé en 2006, est essentiellement consacré à l’étude des « courtisans ». Ses travaux, ainsi que ceux des universitaires français ou étrangers, associent étroitement l’histoire des institutions, des personnes et des pratiques aux lieux de leur exercice. Les expositions annuelles organisées par le château de Versailles assurent la visibilité des différentes orientations de la recherche, convergeant ainsi à la connaissance de l’objet global constitué par le Versailles royal.
<b>Retraction</b>: Neural stem cell conditioned medium alleviates Aβ<sub>25-35</sub> damage to SH-SY5Y cells through the PCMT1/MST1 pathway
Authors: Jia Guoyong , Yang Hongna , Diao Zengyan , Liu Ying , Sun Congcong 
Published: October 2020

On behalf of the coauthors and with much regret, I must retract our publication entitled “Neural stem cell conditioned medium alleviates Aβ25-35 damage to SH-SY5Y cells through the PCMT1/MST1 pathway” published on European Journal of Histochemistry 2020;64(s2):3135 for the following reasons:
In Figure 1A, the data of 20 μM Aβ25-35 for different time were confused with the data of 30 μM Aβ25-35 for different time. In Figure 2, the differential expression of PCMT1 is poor in repeatability. The authors need to revise the experimental design and steps to verify it again, re-do the experiment and conduct a more in-depth study.
Dr. Congcong SunDepartment of NeurologyQilu Hospital CheelooCollege of Medicine Shandong University China
Therapeutic potential of xanthones from Swertia chirata in breast cancer cells
Authors: Barua Atish , Choudhury Pritha , Mandal Suvra , Panda Chinmay Kumar , Saha Prosenjit 
Published: October 2020

Background & objectives:
Medicinal plants like Swertia chirata are rich sources of different xanthones. This study was aimed to assess the cytotoxic potential of four most abundant xanthones present in S. chirata both in vivo and in vitro in Ehrlich ascites carcinoma (EAC), a mouse transplantable breast carcinoma cell line and two human breast carcinoma cell lines (MCF-7 and MDA-MB-231).

Methods:
Four xanthones derived from S. chirata namely 1-hydroxy-3,7,8-trimethoxyxanthone (XA), 1,8-dihydroxy-3,5-dimethoxyxanthone (XB), 1-hydroxy-3,5,8-trimethoxyxanthone (XC) and 1,5,8-trihydroxy-3-methoxyxanthone (XD) were used for determination of sub-lethal dose on the cell lines EAC, MCF-7, MDA-MB-231 and verified toxicity of sub-lethal dose on normal murine fibroblast cells. Cytotoxicity was measured in vivo and survivability of mice was plotted accordingly. Therapeutic efficacy of XD was evaluated both in vivo and in vitro by determination of lipid peroxidation (LPO), reactive oxygen species (ROS) generation and by quantitating the enzyme status (GSH, catalase, superoxide dismutase) in treated and untreated samples. DNA damage was evaluated using comet and DNA fragmentation assays. Furthermore, apoptotic effect was analyzed by flow cytometry and validated by TUNEL assay and Western blotting.

Results:
Among all the xanthones tested XD showed IC50 at the lowest dose, and normal cells were unaffected at this dose. Survivability of mice increased significantly when treated with XD compared to other xanthones and cisplatin. Significantly increased ROS and LPO were found in cancer cells as a result of XD treatment which was unaltered in normal cell line. XD induced DNA damage and apoptosis in cancer cell lines.

Interpretation & conclusions:
Our experimental data indicate that XD may potentially act as a chemotherapeutic agent by enhancing ROS in breast cancer cells thereby leading to apoptosis.
Study of long non-coding RNA highly upregulated in liver cancer (HULC) in breast cancer
Authors: Gavgani Reyhaneh Ravanbakhsh , Babaei Esmaeil , Hosseinpourfeizi Mohammad Ali , Fakhrjou Ashraf , Montazeri Vahid 
Published: October 2020

Background & objectives:
Breast cancer remains the most common malignancy among women worldwide. Long non-coding RNAs (lncRNAs) have been shown to play critical roles in tumour initiation and progression. This study was aimed to evaluate the potential role of lncRNA highly upregulated in liver cancer (HULC) in breast cancer.

Methods:
The expression of HULC was evaluated in breast cancer patients and cell lines using real-time quantitative reverse transcription polymerase chain reaction. Small interfering RNA-based knockdown was also employed to study the potential role of HULC in breast cancer cell lines including ZR-75-1, MCF7 and MDA-MB-231.

Results:

HULC was significantly upregulated in tumour tissues compared to non-tumoural margins (P<0.001). The receiver operating characteristic (ROC) curve analysis demonstrated the biomarker potential of HULC (ROCAUC=0.78, P<0.001). The HULC knockdown induced apoptosis and suppressed cellular migration in breast cancer cell lines.

Interpretation & conclusions:
Our results indicated that HULC was upregulated in breast cancer and might play a role in tumourigenesis. The HULC may have a potential to be exploited as a new biomarker and therapeutic target in breast cancer.
Materiale document: primii ani ai Facultății de Silvicultură din Suceava
Authors: Horodnic Sergiu Andrei 
Published: October 2020

Rubrica „Restituiri” este dedicată aniversării celor 30 ani de învățământ silvic superior la Suceava și grupează trei dintre materialele–document ce sunt readuse atenției cititorilor cu scopul vădit de a le primeni amintirile unora sau de a oferi altora câteva pagini din istoria acestei instituții ce ar fi putut rămâne ascunse în rafturile prăfuite ale arhivei.
Pentru a înțelege cum a luat ființă Facultatea de Silvicultură din Suceava este nevoie de un exercițiu de imaginație pentru cei care nu au fost direct implicați, care necesită totuși niște repere de prezentare a contextului general al stării Universității „Ștefan cel Mare” în 1990. Astfel se justifică includerea unui prim material ce oferă informații privind cadrul existent la acea vreme, cu câteva referiri la istoricul Institutului de Învățământ Superior din Suceava, la numărul de studenți pe profiluri și forme de învățământ la momentul transformării în Universitate, la spațiile de învățământ și cadrele didactice existente, precum și, foarte interesant pentru facultatea noastră, o listă cu cadre didactice propuse a fi încadrate la specializarea „Silvicultură și Exploatare Forestieră”, cum s-a intenționat să se numească inițial.
Perioada de început, anevoioasă şi plină de provocări, a fost marcată de puternica personalitate a profesorului Ioan Milescu, cel care şi-a asumat responsabilitatea conducerii proaspăt înfiinţatei facultăţi în calitate de decan. Următoarele două documente reprezintă dovezi ale profesionalismului, tactului şi spiritului progresist care l-au caracterizat.
„Învăţământ silvic superior la Suceava” este, pe de o parte, o declaraţie de ataşament la valorile tradiţionale şi o expresie a misiunii asumate de promovare a unui învățământ modern, iar pe de altă parte un apel la dezvoltarea colaborării cu Facultatea de Silvicultură și Exploatări Forestiere din Brașov în „aceeași misiune nobilă, (…) susținându-se și completându-se în direcția aceluiași scop final”. „Am împărtășit și susținut opinia că existența mai multor școli de același profil și nivel între fruntariile țării are menirea de a stimula procesul de învățământ și de cercetare științifică”, spunea profesorul Ioan Milescu.
Profilul profesional al viitorului inginer forestier este tema lucrării „Formarea specialiștilor silvici pentru silvicultura secolului XXI” susţinută la Academia Română în martie 1992. Ideile expuse atunci sunt mai valabile ca oricând astăzi: formarea unor „specialiști integri, cu o largă orientare spre viitor”, „flexibilitatea procesului de învățământ”, pregătirea absolvenţilor complex şi multidisciplinar astfel încât aceştia „să gândească și să acționeze în mod independent, eliberați de stresul obligativității de a se încadra strict în norme sau diferite alte proceduri cu pretenții de generalizare”. Profesorul Ioan Milescu atenţiona cu acea ocazie asupra unui mare pericol: „aspectele unor atitudini sau politici conjuncturale, ca și tentativele de a considera pădurea capital electoral se dovedesc dezastruoase pentru viitorul silviculturii”. Vi se pare cunoscut?
Rolul și rolurile cercetării științifice în consolidarea Facultății de silvicultură din Suceava
Authors: Drăgoi Marian 
Published: October 2020

Articolul prezintă o serie de personalități ale cercetării științifice ce au contribuit semnificativ la edificarea Facultății de Silvicultură din Suceava. Pe lângă cele trei cadrele didactice în prezent titulare (autorul articolului, prof Radu cenușă și conf. Mihai-Leonard Duduman) aducem un cald omagiu celorlalți cercetători ce au predat diverse discipline că titulari sau in regim de plata cu ora (acad. dr.ing. Victor Giurgiu, dr.ing. Constantin Roșu dr.ing. Ion Barbu, dr.ing. Nicolai Olenici), dar, mai ales, celor patru mari anonimi care, indirect, prin sugestiile făcute și donațiile de carte, au ajutat la crearea unui plan de învățământ modern, chiar dacă nu toate disciplinele pe care le-au propus inițial s-au regăsit în acesta. Respectivele personalități au fost dr.ing. Radu Ichim, dr.ing. Constantin Bândiu, dr.ing. Nicolae Geamabașu și dr.ing. Radu Dissescu.
Recenzii
Authors: Drăgoi Marian , Irimia Irina 
Published: October 2020

Albert-László Barabási: Formula – Legile universale ale succesului. Editura trei, București, 2020. 337 p. ISBN 978-606-40-0769-8
Cezar Valentin Tomescu, Taxonomie vegetală, Editura Universității ”Ștefan cel Mare” Suceava, 2020, 201 p. ISBN 978-973-666-600-1
Legal regulation of Islamic leasing in the republic of Uzbekistan
Authors: Bozarov Shavkat 
Published: October 2020

Considered the correlation between the legal regulation of conventional leasing relations in the Republic of Uzbekistan and the legal regulation of one of the most dynamically developing Islamic products in the world - Islamic leasing, Ijara.
Evaluated the possibilities of applying the current legislation of the Republic of Uzbekistan regulating conventional leasing relations to Islamic leasing – Ijara. Considered the application of the most important provisions of the current leasing legislation of the Republic of Uzbekistan in relation to the regulation of Ijara
Proved the possibility of implementing Islamic leasing – Ijara on the basis of the current leasing legislation of the Republic of Uzbekistan and presented proposals for a wider implementation of this type of financial services.
Layout optimization for offshore wind farms in India using the genetic algorithm technique
Authors: Reddy Narender Kangari , Baidya Roy Somnath 
Published: October 2020

Abstract. Wind Farm Layout Optimization Problem (WFLOP) is a critical issue
when installing a large wind farm. Many studies have focused on the WFLOP
but only for a limited number of turbines and idealized wind speed
distributions. In this study, we apply the Genetic Algorithm (GA) to solve
the WFLOP for large hypothetical offshore wind farms using real wind data.
GA mimics the natural selection process observed in nature, which is the
survival of the fittest. The study site is the Palk Strait, located between
India and Sri Lanka. This site is a potential hotspot of offshore wind in
India. A modified Jensen wake model is used to calculate the wake losses. GA is used to produce optimal layouts for four different wind farms at the
specified site. We use two different optimization approaches: one where the
number of turbines is kept the same as the thumb rule layout and another
where the number of turbines is allowed to vary. The results show that
layout optimization leads to large improvements in power generation (up to
28 %), efficiency (up to 34 %), and cost (up to 25 %) compared to the
thumb rule due to the reduction in wake losses. Optimized layouts where both the number and locations of turbines are allowed to vary produce better results in terms of efficiency and cost but also leads to lower installed capacity and power generation. Wind energy is growing at an unprecedented rate in India. Easily accessible terrestrial wind resources are almost saturated, and offshore wind is the new frontier. This study can play an important role while taking the first steps towards the expansion of offshore wind in India.
Tropopause-level planetary wave source and its role in two-way troposphere–stratosphere coupling
Authors: Boljka Lina , Birner Thomas 
Published: October 2020

Abstract. Atmospheric planetary waves play a fundamental role in driving stratospheric dynamics, including sudden stratospheric warming (SSW) events. It is well established that the bulk of the planetary wave activity originates near the surface. However, recent studies have pointed to a planetary wave source near the tropopause that may play an important role in the development of SSWs. Here we analyze the dynamical origin of this wave source and its impact on stratosphere–troposphere coupling, using an idealized model and a quasi-reanalysis. It is shown that the tropopause-level planetary wave source is associated with nonlinear wave–wave interactions, but it can also manifest as an apparent wave source due to transient wave decay. The resulting planetary waves may then propagate deep into the stratosphere, where they dissipate and may help to force SSWs. Our results indicate that SSWs preceded by both the tropopause and the surface wave-source events tend to be followed by a weakened tropospheric zonal flow several weeks later. However, while in the case of a preceding surface wave-source event this downward impact is found mainly poleward of 60∘ N, it appears to be the strongest between 40 and 60∘ N for SSWs preceded by tropopause wave-source events. This suggests that tropopause wave-source events could potentially serve as an additional predictor of not only SSWs but also their downward impact as well.
Process optimization of ultrasonication-assisted extraction to obtain antioxidant-rich extract from Spirulina platensis
Authors: Pyne Smriti Kana , Bhattacharjee Paramita , Srivastav Prem Prakash 
Published: October 2020

In this study highlights on the optimization of extraction process parameters of total phenolic content and antioxidant activity from Spirulina platensis, through ultrasonication (probe) technology. Especially, optimization of ultrasonication parameters was carried out employing Box-Behnken Design (BBD) and response surface methodology. Alongside the three levels of extraction parameters i.e. solvent volume, extraction time and frequency have been fixed. As responses, the total yield of extract, total phenolic content and DPPH radical scavenging activity (IC50) of the extracts were determined. The variability of each response variable was determined by developing multiple linear regressions. The statistical analysis (ANOVA) of developed mathematical models allowed the prediction of the behaviour of the responses, as a function of the variables involved in the process. The optimized extraction conditions were obtained at 58.76 kHz frequency, 10 mL of solvent volume for 6 min. Simultaneously this extract exhibited the highest content of total phenolic content (30.89 mg GAE/g powder), IC50 for DPPH activity (151.27 µg/mL). The extract exhibited an important antioxidant i.e. caffeic acid, which was quantified as 660.72±41.05 µg/g of dry algal powder using HPLC. In spite of fact that, this study offers an alternative method for obtaining natural antioxidants from algae for food and pharmaceutical applications. Keywords: Microalgae; Probe sonication extraction; Total phenolic content; Antioxidant activity
Effect of Control on the Mathematical Model of Hepatitis B Virus with Infective Migrant
Authors: Akinboro Folahan S. , Oluyo T. O. , Kehinde O. O. , Alao S. 
Published: October 2020

The transmission dynamics of Hepatitis B Virus in a population with infective immigrant is presented with the inclusion of an optimal control strategy to curtail the spread of the virus. To understand the spread of this infection, we develop a mathematical model with control variables of migrant screening and public sensitization. The optimality system is characterized using Pontryagin’s maximum principle and solve numerically with an implicit finite difference method. Result of the numerical simulation is presented to illustrate the feasibility of this control strategy. The analysis reveals that combination of both control variables could be the most fruitful way to reduce the incidence of Hepatitis B virus.
Accelerated Ripening Agents and Their Effect on the Quality of Avocado (Persia americana M.) and Mango (Mangifera indica L.) Fruits
Authors: Orisa C. A. , Usoroh C. I. , Ujong A. E. 
Published: October 2020

The natural process of fruit ripening is a combination of physiological, biochemical and molecular processes which can be activated or accelerated artificially by using different chemical agents. This study was carried out to examine the effects of three ripening process on the quality of avocado and mango fruits. Freshly unripe mango and avocado fruits were treated with calcium carbide powder, kerosene fumes and ripening in woven polypropylene bags. Calcium carbide treated fruits were stored for 48 hrs and all the samples were fully ripened except avocado fruit. The kerosene fumed fruits were stored for 24 hrs and then exposed to open air for another 24 hrs. Fruits ripened in empty plastic rice got ripened within 4 and 5 days for mango and avocado, respectively. The fruits were then analyzed for their physicochemical properties and sulphide and sulphate distributions using standard methods. The result revealed a decrease in TTA, pH, carbohydrate and vitamin C contents on ripening. On the other hand, moisture and TSS was observed to increase. However, accelerated ripening had no significant (p<0.05) effect on the moisture and vitamin C content of the fruits. Mango samples treated with calcium carbide recorded higher acidity (0.92%) and low pH (3.08) than those treated with kerosene (0.29% and 3.71%, respectively). Sulphide and sulphate distribution of avocado was found to increase after accelerated ripening with kerosene fumes. A decrease for sulphate (outer distribution) and increase for sulphate (inner) and sulphide (outer) was observed for mango fruits. The results also showed that ripening in woven polypropylene had no significant (p<0.05) effect on the TTA of the fruits while pH, moisture and TSS varied significantly (p<0.05) with fruit type. The use of calcium carbide for fruit ripening is not advisable.