bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rethinking creative intelligence: comparative psychology and the concept of creativity
Authors: Shevlin Henry 
Published: December 2020

AbstractThe concept of creativity is a central one in folk psychological explanation and has long been prominent in philosophical debates about the nature of art, genius, and the imagination. The scientific investigation of creativity in humans is also well established, and there has been increasing interest in the question of whether the concept can be rigorously applied to non-human animals. In this paper, I argue that such applications face serious challenges of both a conceptual and methodological character, reflecting deep controversies within both philosophy and psychology concerning how to define and apply the concept of creativity. After providing a brief review of some of the leading theories of creativity (Section 2) and discussing some of the strongest putative cases of creative intelligence in non-human animals (Section 3), I examine some of the more worrisome difficulties faced by attempts to use these theories to answer the question of whether animals are truly creative (Section 4). I conclude by examining how we might overcome them, and suggest that one approach worth taking seriously is to adopt what I term aStrong Rejectionistview of creativity, eschewing use of the term entirely in the scientific study of comparative cognition.
Using Geodesign as a boundary management process for planning nature-based solutions in river landscapes
Authors: Gottwald Sarah , Brenner Jana , Janssen Ron , Albert Christian 
Published: December 2020

AbstractPlanning with nature-based solutions (NBS) presents a participatory approach that harnesses actions supported by nature to address societal challenges. Whilst Geodesign may facilitate participatory planning, manage boundaries between participants, and assess impacts of NBS, empirical insights remain scarce. This paper aims to develop and test a Geodesign process for planning with NBS, and to evaluate its contributions to boundary management. In a one-day Geodesign process, eleven stakeholders delineated priority areas, changed land uses, and observed resulting impacts on ecosystem services. Contributions to boundary management were evaluated regarding translation, communication and mediation functions, as well as perceived attributions of credibility, salience, and legitimacy. Results include spatial NBS scenarios and insights into contributions to boundary management: translating scenario stories into maps differed depending on the stakeholders involved; communication can be easily facilitated; yet mediation using an indicator tool led to frustration. Geodesign can indeed facilitate NBS co-design but needs to be integrated into a larger collaborative process.
Understanding familial liability for emotion regulation difficulties in bipolar disorder
Authors: Van Rheenen Tamsyn E. , Miskowiak Kamilla , Karantonis James , Furlong Lisa S. , Murray Greg , Rossell Susan L. 
Published: December 2020

AbstractBackgroundThere has been relatively limited work focused on understanding whether relatives of individuals with bipolar disorder (BD) have difficulties in the regulation of emotion, particularly in relation to perceptions about whether emotions can be effectively regulated, or trait behaviours that acknowledge emotions as self-regulators themselves. In this study, we assessed the presence and extent of difficulties in these dimensions of emotion regulation in individuals with BD compared to unaffected first-degree biological relatives (FDR) for the first time.MethodsIn total, 161 participants, including euthymic individuals with BD, unaffected FDRs, and healthy controls, were compared on the Difficulties in Emotion Regulation Scale (DERS) – a multi-dimensional measure of habitual emotion regulation. Clinical data were also collected and examined in relation to DERS scores in a secondary analysis.ResultsIn the BD group, difficulties were evident for most dimensions of emotion regulation as measured by the DERS; and correlated with an earlier onset of illness and more mood episodes. FDRs displayed generally normal emotion regulation, except in terms of their beliefs that emotions can be effectively regulated; on this dimension, their reported difficulty was intermediate to the BD group and controls.ConclusionHabitual emotion regulation difficulties in BD persist irrespective of mood state, are related to the course of illness, and should be targeted in psychological interventions. Further, the perception that emotions cannot be effectively regulated during times of distress seems to represent an endophenotype for BD.
Lysimache and Lysistrata
Authors: Thonemann Peter 
Published: December 2020

Abstract:It has long been suspected that the eponymous heroine of Aristophanes’ Lysistrata was intended to evoke the historical Lysimache, priestess of Athena Polias at the time of the play’s first production. But the reasons for this (partial) identification have been relatively little discussed. This paper argues that the Lysistrata engages more closely than has traditionally been assumed with urgent political issues at Athens in late 412 and early 411 BC, in particular with the decision in summer 412 BC to broach the ‘Iron Reserve’ of 1,000 talents set aside at the beginning of the Peloponnesian War (Thuc. 8.15.1). A possible intervention of the historical Lysimache in the controversy over the appropriate use of the ‘Iron Reserve’ would help account for various otherwise surprising features of the Lysistrata.
Authentic learning in senior secondary music pedagogy: an examination of teaching practice in high-achieving school music programmes
Authors: White Rachel 
Published: December 2020

AbstractAuthentic learning approaches are designed to immerse students in contexts that promote real-life applications of knowledge, and provide meaningful learning experiences beyond the abstract instruction of the classroom. In a grounded theory study of music teaching practice in high-achieving schools, 50 teachers from 23 schools across New South Wales (NSW), Australia, were asked to describe how they taught their senior secondary students and the musical environment they curated within their school. Through examination of the interview data, authentic learning exposed itself as uniquely situated in classroom music teaching of high-achieving music programmes for senior secondary students in NSW. This is shown through the use of thorough inquiry-based and student-centred learning tasks like video journals, the use of professional resources and expertise and collaborative learning in authentic contexts, in and outside of the classroom.
Shrub canopy interception of diaspores dispersed by wind
Authors: Qin Xuanping , Liu Zhimin , Liu Minghu , Liang Wei , Baskin Carol C. , Baskin Jerry M. , Xin Zhiming , Li Xinle , Wang Zhigang , Zhou Quanlai , Luo Fengmin , Gao Junliang , Naren Gerile 
Published: December 2020

AbstractInterception by plant canopies during wind dispersal can affect the final destination of diaspores. However, how the interaction of wind speed, canopy type and diaspore attributes affects interception of diaspores by the plant canopy has rarely been studied. We investigated canopy interception for 29 species with different diaspore attributes, six canopy types and six wind speeds in controlled experiments in a wind tunnel. Shrub canopy interception of diaspores were controlled by wind speed and diaspore attributes, but the latter had a greater influence on canopy interception than the former. At low wind speed, diaspore wing loading had a large influence on canopy interception, whereas at high wind speed, diaspore projection area had a large influence. The chance of canopy interception at a particular wind speed was additionally affected by the type of canopy. This study increases our knowledge of the dispersal process, corrects the previous understanding of diaspore dispersal potential and improves the theoretical basis for predicting spatial pattern and dynamics of plant populations.
Unusual coronary artery arrangement in D-transposition of the great arteries with ventricular septal defect
Authors: Bhimani Salima Ahmed , Komarlu Rukmini 
Published: December 2020

A term female with prenatally diagnosed D-Transposition of the great arteries, large membranous ventricular septal defect with inlet extension, moderate secundum atrial septal defect, and large patent ductus arteriosus (Fig 1) was born by scheduled caesarean section. Transthoracic echocardiogram confirmed the anatomy with both coronary arteries arising from a single sinus with separate ostia. The right coronary artery arose from right posterior facing sinus (Fig 2). The left coronary artery arose anomalously from the same sinus adjacent to the right coronary artery ostium, coursing posterior to the aorta, with brief intramural and interarterial course before bifurcating into the left anterior descending and left circumflex coronary arteries (Figs 3 and 4). As a result of this unique coronary pattern, she underwent unroofing of the intramural left coronary artery noted on opening the aortic root to the coronary ostium. Both coronary buttons were harvested and this large button was then divided into two buttons. The left coronary artery button was implanted with a trapdoor technique, right coronary artery button was implanted, and the remainder of the arterial switch procedure along with LeCompte maneuver was completed uneventfully, with closure of the atrial and ventricular septal defects. The post-operative course was uneventful and the patient was discharged on the seventh post-operative day. At discharge, the patient had normal biventricular systolic function, no residual intracardiac shunt, and robust antegrade flow in the reimplanted coronary arteries. The patient was growing well at the fourth month post-operative visit with normal biventricular function, patent coronaries, and outflow tracts.
Rethinking Mass-Gathering Domains for Understanding Patient Presentations: A Discussion Paper
Authors: Hutton Alison , Ranse Jamie , Zimmerman Peta-Anne 
Published: December 2020

AbstractAim:The aim of this paper is to further develop an existing data model for mass-gathering health outcomes.Background:Mass-gathering events (MGEs) occur frequently throughout the world. Having an understanding of the complexities of MGEs is important to determine required health resources. Environmental, psychosocial, and biomedical domains may be a logical starting point to determine how data are being collected and reported in the literature; however, it may be that other factors influencing health resources are not identified within these domains.Method:Based on an exhaustive literature synthesis, this paper is the final paper in a series that explores the collection of variables that impact biomedical presentations associated with attendance/participation in MGEs.Findings:The authors propose further evolution of the Arbon model to include the addition of several domains, including: event environment; command, control, and communication (C3); public health; health promotion; and legacy when reporting the health outcomes of an event.Conclusions:Including a variety of domains that contribute to an MGE allows for formal evaluation of the event, which in turn informs future knowledge and skill development for both the event management group and the wider community.
When Sino-American Struggle Disrupts the Supply Chain: Licensing Intellectual Property in a Changing Trade Environment
Authors: Cohen Mark A. , Rogers Philip C. 
Published: December 2020

AbstractThrough legislative changes, tariff wars, and executive actions, the Trump Administration has injected a new urgency into international technology and supply chain management, particularly between the United States and China. Analytically, the situation invites a perspective that links practical/on-the-ground responses by commercial actors in the politics of technological competition between superpowers, i.e. a discussion that bridges the gap between policy and process. This article therefore approaches management of supply chain disruption in terms of a key security issue motivating recent changes to the trade environment: the protection of intellectual property. After reviewing critical policy developments and trade statistics, we draw upon data on IP-intensive industries from global patent offices, trade classifications for products made by these IP-intensive industries, and concordance data on patent classifications to illustrate the centrality of IP to extended supply chains. With these key relationships in mind, we outline specific opportunities that intellectual property licensing provides for managing supply chain linkages between the United States and China in the current geopolitical environment. Viewing intellectual property as both a driver of and a solution to trade difficulties highlights the sorts of cross-jurisdictional nuances that can better inform policy and business decisions alike in the broader international trade regime.
Design of elliptical-shaped reconfigurable patch antenna with shunt capacitive RF-MEMS switch for satellite applications
Authors: Sailaja Bokkisam Venkata Sai , Naik Ketavath Kumar 
Published: December 2020

AbstractIn this paper, non-uniform meandered line shunt capacitive RF-MEMS switch is presented at an elliptical patch etched with a split-ring resonator (SRR) for satellite communication applications. The non-uniform meander line shunt capacitive is a fixed-fixed type of RF-MEMS switch that is introduced in this model antenna. The proposed antenna design is resonated at 10.46 GHz with the return loss of −37.6 dB. The performance evolution of the proposed antenna design is evaluated with and without integrated RF-MEMS switch on the proposed antenna SRR. It is observed that the proposed model at the ON-state switch resonates at 10.57 GHz frequency with the return loss of −30 dB. Similarly, at the OFF-state switch, it resonates at 10.53 GHz frequency with the return loss of −43 dB. Al3N4 (aluminum nitride) is used for the switch as a dielectric material, hence the switch attains higher isolation. The actuation voltage of 7.9 V is required for the switch to actuate from ON to OFF state. The switch attains minimum insertion and return loss which is discussed in further sections. The proposed antenna is fabricated and tested by a vector network analyzer; there is a good agreement between the simulated and measured results.
Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy
Authors: Wisdom Amy J. , Mowery Yvonne M. , Hong Cierra S. , Himes Jonathon E. , Nabet Barzin Y. , Qin Xiaodi , Zhang Dadong , Chen Lan , Fradin Hélène , Patel Rutulkumar , Bassil Alex M. , Muise Eric S. , King Daniel A. , Xu Eric S. , Carpenter David J. , Kent Collin L. , Smythe Kimberly S. , Williams Nerissa T. , Luo Lixia , Ma Yan , Alizadeh Ash A. , Owzar Kouros , Diehn Maximilian , Bradley Todd , Kirsch David G. 
Published: December 2020

AbstractImmunotherapy fails to cure most cancer patients. Preclinical studies indicate that radiotherapy synergizes with immunotherapy, promoting radiation-induced antitumor immunity. Most preclinical immunotherapy studies utilize transplant tumor models, which overestimate patient responses. Here, we show that transplant sarcomas are cured by PD-1 blockade and radiotherapy, but identical treatment fails in autochthonous sarcomas, which demonstrate immunoediting, decreased neoantigen expression, and tumor-specific immune tolerance. We characterize tumor-infiltrating immune cells from transplant and primary tumors, revealing striking differences in their immune landscapes. Although radiotherapy remodels myeloid cells in both models, only transplant tumors are enriched for activated CD8+ T cells. The immune microenvironment of primary murine sarcomas resembles most human sarcomas, while transplant sarcomas resemble the most inflamed human sarcomas. These results identify distinct microenvironments in murine sarcomas that coevolve with the immune system and suggest that patients with a sarcoma immune phenotype similar to transplant tumors may benefit most from PD-1 blockade and radiotherapy.
Readout and control of an endofullerene electronic spin
Authors: Pinto Dinesh , Paone Domenico , Kern Bastian , Dierker Tim , Wieczorek René , Singha Aparajita , Dasari Durga , Finkler Amit , Harneit Wolfgang , Wrachtrup Jörg , Kern Klaus 
Published: December 2020

AbstractAtomic spins for quantum technologies need to be individually addressed and positioned with nanoscale precision. C60 fullerene cages offer a robust packaging for atomic spins, while allowing in-situ physical positioning at the nanoscale. However, achieving single-spin level readout and control of endofullerenes has so far remained elusive. In this work, we demonstrate electron paramagnetic resonance on an encapsulated nitrogen spin (14N@C60) within a C60 matrix using a single near-surface nitrogen vacancy (NV) center in diamond at 4.7 K. Exploiting the strong magnetic dipolar interaction between the NV and endofullerene electronic spins, we demonstrate radio-frequency pulse controlled Rabi oscillations and measure spin-echos on an encapsulated spin. Modeling the results using second-order perturbation theory reveals an enhanced hyperfine interaction and zero-field splitting, possibly caused by surface adsorption on diamond. These results demonstrate the first step towards controlling single endofullerenes, and possibly building large-scale endofullerene quantum machines, which can be scaled using standard positioning or self-assembly methods.
Analysis and prediction of the coronavirus disease epidemic in China based on an individual-based model
Authors: Guo Zuiyuan , Xiao Dan 
Published: December 2020

AbstractWe established a stochastic individual-based model and simulated the whole process of occurrence, development, and control of the coronavirus disease epidemic and the infectors and patients leaving Hubei Province before the traffic was closed in China. Additionally, the basic reproduction number (R0) and number of infectors and patients who left Hubei were estimated using the coordinate descent algorithm. The median R0 at the initial stage of the epidemic was 4.97 (95% confidence interval [CI] 4.82–5.17). Before the traffic lockdown was implemented in Hubei, 2000 (95% CI 1982–2030) infectors and patients had left Hubei and traveled throughout the country. The model estimated that if the government had taken prevention and control measures 1 day later, the cumulative number of laboratory-confirmed patients in the whole country would have increased by 32.1%. If the lockdown of Hubei was imposed 1 day in advance, the cumulative number of laboratory-confirmed patients in other provinces would have decreased by 7.7%. The stochastic model could fit the officially issued data well and simulate the evolution process of the epidemic. The intervention measurements nationwide have effectively curbed the human-to-human transmission of severe acute respiratory syndrome coronavirus 2.
Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens
Authors: Kitamura Koji , Nimura Keisuke , Ito Rie , Saga Kotaro , Inohara Hidenori , Kaneda Yasufumi 
Published: December 2020

AbstractHuman papillomavirus (HPV) 16 infection in the oropharynx is one of the major risk factors for oropharyngeal carcinoma. Although the HPV E6 and E7 proteins are known to have a role in head and neck carcinogenesis, whether their expression is maintained once the tumour has developed still remains unclear. We evaluated the expression of these proteins in HPV16-positive cancer cell lines and clinical oropharyngeal specimens. Two out of the four commercially available antibodies directed against the E7 protein could detect the E7 protein overexpressed in the 293FT cells, human embryonic kidney cells, although none of the four commercially available anti-E6 antibodies could detect the overexpressed E6 protein. Whereas HPV16-positive head and neck or cervical carcinoma cell lines expressed the E7 mRNA, the antibodies with an ability to detect the E7 protein could not detect it in western blotting in these HPV16-positive cell lines. In clinical specimens, E7 protein was partially detected in p16-positive area in p16-positive and HPV16 DNA-positive samples, but not in p16-negative and HPV DNA-negative or p16-positive and HPV DNA-negative samples. Consistent with these findings, the E7 protein was poorly translated from the endogenous structure of the E7 mRNA, although significant E7 mRNA expression was detected in these samples. Our findings indicate that E7 protein is partially expressed in p16-positive area in p16-positive and HPV16 DNA-positive clinical specimens.
Involvement of N-methylpurine DNA glycosylase in resistance to temozolomide in patient-derived glioma cells
Authors: Serrano-Heras Gemma , Castro-Robles Beatriz , Romero-Sánchez Carlos M. , Carrión Blanca , Barbella-Aponte Rosa , Sandoval Hernán , Segura Tomás 
Published: December 2020

AbstractChemotherapy for high-grade astrocytic tumors is mainly based on the use of temozolomide (TMZ), whose efficacy is limited by resistance mechanisms. Despite many investigations pointing to O6-methylguanine-DNA-methyltransferase (MGMT) as being responsible for tumor chemo-resistance, its expression does not predict an accurate response in most gliomas, suggesting that MGMT is not the only determinant of response to treatment. In this sense, several reports indicate that N-methylpurine-DNA-glycosylase (MPG) may be involved in that resistance. With that in mind, we evaluated for the first time the degree of resistance to TMZ treatment in 18 patient-derived glioma cells and its association with MGMT and MPG mRNA levels. Viability cell assays showed that TMZ treatment hardly caused growth inhibition in the patient-derived cells, even in high concentrations, indicating that all primary cultures were chemo-resistant. mRNA expression analyses showed that the TMZ-resistant phenotype displayed by cells is associated with an elevated expression of MPG to a greater extent than it is with transcript levels of MGMT. Our findings suggest that not only is MGMT implicated in resistance to TMZ but MPG, the first enzyme in base excision repair processing, is also involved, supporting its potential role as a target in anti-resistance chemotherapy for astrocytoma and glioblastoma.
Job loss and health threatening events modulate risk-taking behaviours in the Covid-19 emergency
Authors: Galandra Caterina , Cerami Chiara , Santi Gaia Chiara , Dodich Alessandra , Cappa Stefano F. , Vecchi Tomaso , Crespi Chiara 
Published: December 2020

AbstractCovid-19 pandemic is exerting a tragic impact all around the world. First-person experience of life-threatening and stressful events can modify individuals’ risk perception, and, consequently, risk-taking behaviours. Here we investigated risk-taking profiles in 130 Italian residents, and compared healthcare to non-healthcare workers, during the lockdown phase. We ad hoc developed the “Covid-19 Risk Task”, including the classic monetary Holt-Laury Paired Lottery Task (Monetary Condition, MC) and two new ecological conditions exploring Covid-19 related risk-taking aptitudes in relation to different health (Health Status Condition, HsC) and employment (Employment Status Condition, EsC) outcomes. Results showed that, in the whole sample, individuals were more risk-averse in MC than in HsC and EsC. Moreover, a payoff increase produced a shift toward more risk-averse behaviours in MC, but not in HsC and EsC, where we found an opposite trend suggesting a more risk-loving behaviour. Finally, we found that healthcare workers were significantly less risk-averse compared to non-healthcare workers in EsC, but not in MC and HsC. These findings provided evidence of the possible effects of Covid-19 outbreak on risk-taking aptitudes. The negative impact on human choices and, consequently, on the whole world economy of this catastrophic life event must not be underestimated.