bluuebunny/crossref_metadata_2025_split huggingface dataset:
What are men's roles and responsibilities in the feminist project for gender egalitarianism?
Authors: Prasad Ajnesh , Centeno Alejandro , Rhodes Carl , Nisar Muhammad Azfar , Taylor Scott , Tienari Janne , Alakavuklar Ozan Nadir 
Published: November 2020

AbstractThe #MeToo and the Time's Up movements have captured the urgency to address systemic manifestations of sexism, patriarchy, and misogyny in all aspects of society. Among the myriad discourses that have been catalyzed by these contemporaneous movements includes one related to the role of men in achieving gender egalitarianism. Men are allocated unearned privilege associated with being a man in a culture that is inherently phallogocentric. This fact alone charges men with the responsibility to account for the discursive and the institutional systems that afford them unearned privilege at certain relational costs that must be borne by women and, concomitantly, the feminine. The #MeToo and the Time's Up movements—which have initiated greater cultural recognition of the problems associated with establishing a society that is predicated on androcentric values—mark a pressing need, one that is much overdue, for men to interrogate the inequitable ways in which gender configures contemporary social relations. As a contribution to this effort, this article draws on reflexive accounts from men academics broadly invested in the study of gender and organizations and who are at different stages of their careers and from dispersed geographical areas, to respond to the question: What are men's roles and responsibilities in the feminist project for gender egalitarianism? In answering this question, these academics, individually and collectively, identify paths for allyship moving forward.
Oncocytic intraductal carcinoma of salivary glands: a distinct variant with TRIM33–RET fusions and BRAF V600E mutations
Authors: Bishop Justin A , Nakaguro Masato , Whaley Rumeal D , Ogura Kanako , Imai Hiroshi , Laklouk Israa , Faquin William C , Sadow Peter M , Gagan Jeffrey , Nagao Toshitaka 
Published: November 2020

AimsSalivary gland intraductal carcinoma (IDC) is a complex ductal neoplasm surrounded by a layer of myoepithelial cells. Recent insights have shown that there are three different types: intercalated duct‐like, with frequent NCOA4–RET fusions; apocrine, with salivary duct carcinoma‐like mutations; and mixed intercalated duct‐like/apocrine, with RET fusions, including TRIM27–RET. In addition, an oncocytic IDC has been described, but it remains unclear whether it represents a fourth variant or simply oncocytic metaplasia of another IDC type. Our aim was to more completely characterize oncocytic IDC.Methods and resultsSix IDCs with oncocytic changes were retrieved from the authors’ archives, from three men and three women ranging in age from 45 to 75 years (mean, 63 years). Five arose in the parotid gland, with one in an accessory parotid gland. Four patients with follow‐up were free of disease after 1–23 months. Several immunostains (S100, mammaglobin, androgen receptor, and p63/p40) and molecular tools (RNA sequencing, RET fluorescence in‐situ hybridisation, BRAF V600E VE1 immunohistochemistry, and Sanger sequencing) were applied. Histologically, the tumours were variably cystic with solid intracystic nodules often difficult to recognise as intraductal. In all, tumour ducts were positive for S100 and mammaglobin, negative for androgen receptor, and completely surrounded by myoepithelial cells positive for p63/p40. Molecular analysis revealed TRIM33–RET in two of six cases, NCOA4–RET in one of six cases, and BRAF V600E in two of six cases. One case had no identifiable alterations.ConclusionsOncocytic IDC shares similarities with intercalated duct‐like IDC. Although additional verification is needed, the oncocytic variant appears to be sufficiently unique to be now regarded as the fourth distinct subtype of IDC. Because of its indolent nature, oncocytic IDC should be distinguished from histological mimics.
Amorphous silica wastes for reusing in highly porous ceramics
Authors: Ketov Aleksandr , Korotaev Vladimir , Rudakova Larisa , Vaisman Iakov , Barbieri Luisa , Lancellotti Isabella 
Published: November 2020

AbstractThe paper analyzes a solution in green manufacturing of foamed or cellular ceramics. The objective of this study was to determine the technical solution for rice husk ash and “tales” of mixed glass cullet reusing based on the specific properties of these materials for creation of spherical holes inside ceramic using the process of coalescence of cellular glass. The paper reports on experimental results obtained from the production of lightweight cellular glass granules produced using glass cullet and rice husk ash. Lightweight cellular glass granules were mixed with clay, pressed and fired in air at 920°C. Clay sintering and the formation of ceramic were followed with the coalescence of cellular structure of glass granules and with the formation of spherical hollows inside the matrix. Density and strength of the fired ceramic bodies were determined. It is observed that the lightweight ceramics with density 900 ÷ 920 kg/m3 possess a compressive strength of about 5 MPa that is acceptable for bricks or tiles manufacture. The utilization of amorphous silica waste for lightweight ceramics manufacture helps in reducing waste disposal concerns and costs associated, and also transforms the waste into an alternative raw material with added value, moreover making the final product cheap.
Effect of temperature on raw whole milk density and its potential impact on milk payment in the dairy industry
Authors: Parmar Puneet , Lopez‐Villalobos Nicolas , Tobin John T. , Murphy Eoin , Buckley Frank , Crowley Shane V. , Kelly Alan L. , Shalloo Laurence 
Published: November 2020

SummaryThe objective of this study was to determine the effect of temperature on whole milk density measured at four different temperatures: 5, 10, 15, and 20 °C. A total of ninety‐three individual milk samples were collected from morning milking of thirty‐two Holstein Friesian dairy cows, of national average genetic merit, once every two weeks over a period of 4 weeks and were assessed by Fourier transform infrared spectroscopy for milk composition analysis. Density of the milk was evaluated using two different analytical methods: a portable density meter DMA35 and a standard desktop model DMA4500M (Anton Paar GmbH, UK). Milk density was analysed with a linear mixed model with the fixed effects of sampling period, temperature and analysis method; triple interaction of sampling period x analysis method x temperature; and the random effect of cow to account for repeated measures. The effect of temperature on milk density (ρ) was also evaluated including temperature (t) as covariate with linear and quadratic effects within each analytic method. The regression equation describing the curvature and density–temperature relationship for the DMA35 instrument was ρ = 1.0338−0.00017T−0.0000122T2 (R2 = 0.64), while it was ρ = 1.0334 + 0.000057T−0.00001T2 (R2 = 0.61) for DMA4500 instrument. The mean density determined with DMA4500 at 5 °C was 1.0334 g cm−3, with corresponding figures of 1.0330, 1.0320 and 1.0305 g cm−3 at 10, 15 and 20 °C, respectively. The milk density values obtained in this study at specific temperatures will help to address any bias in weight–volume calculations and thus may also improve the financial and operational control for the dairy processors in Ireland and internationally.
Teff (Eragrostis tef) processing, utilization and future opportunities: a review
Authors: Barretto Roselle , Buenavista Rania Marie , Rivera Jared Lou , Wang Shuyu , Prasad P.V. Vara , Siliveru Kaliramesh 
Published: November 2020

AbstractThe demand for food production has been constantly increasing due to rising population. In developed countries, for example, the emergence of regional production of old grains that are rarely utilized, along with the production of commonly consumed grains, has gained importance in recent years. These grains, known collectively as ancient or heirloom grains, have offered both farmers and consumers novel ways of cultivation and products with interesting taste, characteristics and nutritional value. Among the 30 000 plant species known, only five cereals currently provide more than 50% of the world's energy intake – bread wheat (Triticum aestivum), rice (Oryza sativa), sorghum (Sorghum bicolor), millets (Panicum sp.) and maize (Zea mays). The excessive utilization of these selected species has a great potential to cause genetic losses and difficulty in bridging future agricultural demands. Teff (Eragrostis tef), an ancient grain extensively cultivated in countries like Eritrea and Ethiopia, provides promising alternatives for new food uses since its nutritional value is significantly higher than most others cereal grains. The absence of gluten allows flexibility in food utilization since it can be directly substituted to gluten‐containing products. The grain also offers an excellent balance of essential amino acids and minerals, which can fulfil the recommended daily intake and eliminates the need for fortification and enrichment. This review provides a general overview of the physical properties and nutritional composition of teff grains related to processing and applications in the food and feed industries. The current status of teff utilization, as well as the challenges in production and commercialization, and future opportunities is presented and discussed.
Quality attributes of fufu in South‐East Nigeria: guide for cassava breeders
Authors: Chijioke Ugo , Madu Tessy , Okoye Benjamin , Ogunka Amaka Promise , Ejechi Mercy , Ofoeze Miriam , Ogbete Chukwudi , Njoku Damian , Ewuziem Justin , Kalu Confidence , Onyemauwa Nnaemeka , Ukeje Blessing , Achonwa Oluchi , Forsythe Lora , Fliedel Geneviève , Egesi Chiedozie 
Published: November 2020

SummaryFufu is a popular traditional fermented wet paste food product from cassava. We examined consumer preferences and quality attributes of fufu in Abia and Imo States of South‐East Nigeria, with special attention to gender differences, for the purpose of providing guidance to breeders. Data were analysed by the use of descriptive and inferential statistics. Participants for the interview were randomly selected from a list of farmers in the study area. Individual (II) interviews were conducted among eighty participants comprising twenty‐six men (32.5%) and fifty‐four women (67.5%). Preferences along the food chain from raw roots to final product were also obtained. Major traits influencing gender‐specific consumer preferences are related to appearance, texture and smell. Smoothness, not sticky, easy to swallow and drawability of fufu appear to be major traits that drive acceptance by both men and women. Big roots and smooth skin are prioritised for raw material. Some quality characteristics are conditioned largely by variety traits, while others can be modified by adjusting the processing methods. The complexity of producing high‐quality fufu makes it imperative to introduce a multidisciplinary approach into breeding programmes.
Assessment of liver fibrosis markers in people with rheumatoid arthritis on methotrexate
Authors: Olsson‐White Debbie A. , Olynyk John K. , Ayonrinde Oyekoya T. , Paramalingam Shereen , Keen Helen I. 
Published: November 2020

AbstractBackgroundUp to 3% of methotrexate (MTX)‐treated rheumatoid arthritis (RA) patients might develop liver fibrosis or cirrhosis, requiring effective screening algorithms.AimsTo assess the utility of non‐invasive liver fibrosis assessment in RA patients on MTX.MethodsFifty‐six patients were recruited from rheumatology outpatient clinics in a public tertiary centre from July 2017 to October 2018. Clinical data was collected. Screening for hepatic fibrosis was performed using transient elastography (TE), aminoaspartate transaminase to platelet ratio index (APRI), Hepascore and Fibrosis‐4 index (FIB‐4). Those with suspected significant liver fibrosis based on these screening tests were assessed by a hepatologist.ResultsTwenty‐seven patients were suspected to have liver fibrosis on screening, including 10/56 (18%) by TE, 20/56 (36%) by Hepascore, 2/56 by APRI (4%) and 1/56 by FIB‐4 (2%). Of these 27 patients, 11 were reviewed by a hepatologist and one diagnosed with significant liver fibrosis. TE, but not APRI, Hepascore or FIB‐4, was found to have 100% sensitivity and 84% specificity (P = 0.029) for hepatologist‐diagnosed liver fibrosis.ConclusionLiver fibrosis develops in a minority of MTX‐treated RA patients. The present study suggests that TE is a more sensitive screening test than APRI, FIB‐4 or Hepascore in the identification of people with RA at risk of hepatic fibrosis.
Diversity in recognition and function of human γδ T cells
Authors: Castro Caitlin D. , Boughter Christopher T. , Broughton Augusta E. , Ramesh Amrita , Adams Erin J. 
Published: November 2020

AbstractAs interest increases in harnessing the potential power of tissue‐resident cells for human health and disease, γδ T cells have been thrust into the limelight due to their prevalence in peripheral tissues, their sentinel‐like phenotypes, and their unique antigen recognition capabilities. This review focuses primarily on human γδ T cells, highlighting their distinctive characteristics including antigen recognition, function, and development, with an emphasis on where they differ from their αβ T cell comparators, as well as from γδ T cell populations in the mouse. We review the antigens that have been identified thus far to regulate members of the human Vδ1 population and discuss what players are involved in transducing phosphoantigen‐mediated signals to human Vγ9Vδ2 T cells. We also briefly review distinguishing features of these cells in terms of TCR signaling, use of coreceptor and costimulatory molecules and their development. These cells have great potential to be harnessed in a clinical setting, but caution must be taken to understand their unique capabilities and how they differ from the populations to which they are commonly compared.
Nursing students learning to care for refugee patients: a qualitative study†
Authors: Evgin D. , Muz G. 
Published: November 2020

BackgroundNursing students should gain cultural knowledge and skills necessary for providing care to all types of patients.AimThis study aimed to determine problems faced by nursing students who care for refugee patients.MethodThe study used phenomenological qualitative design. The sample comprised 25 nursing students who cared for refugee patients in a clinic. Data were analysed using Colaizzi’s seven‐step method following focus group interviews.ResultsTwo themes were identified for the interviews: (i) language barrier: insufficient care and (ii) students’ perspectives on being a refugee. Furthermore, three subthemes were also identified by analysis of the interviews: (i) superficial communication and insufficiency in psychological support, (ii) health problems in difficult living conditions and (iii) unchanged basic human needs and unmet care needs.ConclusionsNursing students find it difficult to care for refugee patients, but nursing education programmes based on culture care improve their knowledge and perceptions and the quality of care they provide to patients from different cultures.Implication for nursing and health policyIn a multicultural society, nursing students must recognize cultural differences. Consequently, a multicultural education programme helps lay the groundwork for successful integration of nursing students in new cultures.
Principal components for morphometric traits in Campolina horses
Authors: Solar Diaz Iara Del Pilar , Strauss Borges Junqueira Gleb , Aparecida Rocha Cruz Valdecy , Albano Araújo de Oliveira Chiara , Nunes de Oliveira Henrique , Miguel Ferreira de Camargo Gregório , Bermal Costa Raphael 
Published: November 2020

AbstractPrincipal component analysis (PCA) was applied to evaluate the genetic variability and relationship between 15 morphometric traits in 91,483 Campolina horses, as well as to propose an index based on an aggregate genotype that promotes a particular selection objective. PCA was applied to the genetic (co)variance matrix among variables. After calculation of the principal components, the breeding values were estimated to obtain an index related to the component that explained most of the variation. The first principal component (PC1) accounted for 97.8% of the total additive genetic variance of the traits. PC1 contrasted animals in terms of body size (wither, back and croup heights, body length, and thoracic girth). PC1 traits showed higher heritabilities and positive and high genetic correlations. An index was obtained (HPC1) with the combination of the breeding values of different traits from PC1 which permitted the use of this index as an aggregate genotype to identify the best animals for selection. The second principal component (PC2) was much smaller and grouped traits related to head and neck morphometry, among others. These traits are commonly used for breed qualification, a fact explaining the small variation in this component. An evaluation of the effect of HPC1 on withers height in two‐trait analysis was also made which provided positive genetic correlations of moderate to high magnitude (0.73–0.86), indicating that selection for this trait (important in Campolina horses) is accounted for in the index. The use of HCP1 could be considered as an important alternative to selection since it does not consider a single trait but rather a set of variables that capture body proportions.
Biogeographical divides delineated by the three‐step landforms of China and the East China Sea: Insights from the phylogeography of Kerria japonica
Authors: Luo Dong , Xu Bo , Li Zhi‐Min , Sun Hang 
Published: November 2020

AbstractAimEast Asia exhibits complex geomorphological and climatic characteristics. The aim of this study was to test whether the so‐called three‐step landforms of China, together with the East China Sea (ECS), have acted to shape specific phylogeographical patterns and affected the biogeographical history of the species belonging to the East Asian Flora.LocationChina and Japan.TaxonKerria japonica (L.) DC.MethodsThree chloroplast DNA regions and 15 nuclear microsatellite (nSSR) loci were sequenced and genotyped in 576/450 individuals of K. japonica. Phylogeographical analyses were performed to assess the genetic structure, historical gene flow and demographical history of these individuals, and climatic factors were examined to determine their effects on phylogeographical breaks. Furthermore, time‐calibrated phylogenetic trees and ancestral range reconstruction were used to infer the biogeographical history of K. japonica. Potential habitats at present and during the last glacial maximum (LGM) were identified using ecological niche modelling.ResultsDistinct phylogeographical breaks were found across the ECS and along the boundary of the three‐step landforms of China. Low historical gene flow and significant climatic differences were detected in each pair of adjacent regions. The results of molecular dating and ancestral range reconstruction indicated that K. japonica originated in North America during the mid‐Miocene (14.76 Ma), and intra‐specific diversification began in the late Miocene (7.78 Ma). Compared to the relatively stable distribution range of Chinese populations, Japanese populations experienced range expansion after the LGM in response to Quaternary climate change.Main conclusionsKerria japonica has a complex biogeographical history, with a mid‐Miocene origin in North America and subsequent migration into East Asia via the Bering land bridge. The onset of intra‐specific diversification was probably associated with Asian monsoon intensifications, while exposure to the ECS floor facilitated the formation of the Japanese lineage in the late Miocene. The spatiotemporal population differentiation on the Chinese mainland demonstrates the significant role of biogeographical divides delineated by the three‐step landforms of China and provides clues to understand the floristic regionalization and evolutionary history of plant diversity in East Asia, especially with respect to the Hengduan Mountains, Central China and East China.
Tris DBA ameliorates IgA nephropathy by blunting the activating signal of NLRP3 inflammasome through SIRT1‐ and SIRT3‐mediated autophagy induction
Authors: Wu Chung‐Yao , Hua Kuo‐Feng , Yang Shin‐Ruen , Tsai Yi‐Shan , Yang Shun‐Min , Hsieh Chih‐Yu , Wu Chia‐Chao , Chang Jia‐Feng , Arbiser Jack L. , Chang Chiz‐Tzung , Chen Ann , Ka Shuk‐Man 
Published: November 2020

AbstractTris (dibenzylideneacetone) dipalladium (Tris DBA), a small‐molecule palladium complex, can inhibit cell growth and proliferation in pancreatic cancer, lymphocytic leukaemia and multiple myeloma. Given that this compound is particularly active against B‐cell malignancies, we have been suggested that it can alleviate immune complexes (ICs)–mediated conditions, especially IgA nephropathy (IgAN). The therapeutic effects of Tris DBA on glomerular cell proliferation and renal inflammation and mechanism of action were examined in a mouse model of IgAN. Treatment of IgAN mice with Tris DBA resulted in markedly improved renal function, albuminuria and renal pathology, including glomerular cell proliferation, neutrophil infiltration, sclerosis and periglomerular inflammation in the renal interstitium, together with (Clin J Am Soc Nephrol. 2011, 6, 1301‐1307) reduced mitochondrial ROS generation; (Am J Physiol‐Renal Physiol. 2011. 301, F1218‐F1230) differentially regulated autophagy and NLRP3 inflammasome; (Clin J Am Soc Nephrol. 2012, 7, 427‐436) inhibited phosphorylation of JNK, ERK and p38 MAPK signalling pathways, and priming signal of the NLRP3 inflammasome; and (Free Radic Biol Med. 2013, 61, 285‐297) blunted NLRP3 inflammasome activation through SIRT1‐ and SIRT3‐mediated autophagy induction, in renal tissues or cultured macrophages. In conclusion, Tris DBA effectively ameliorated the mouse IgAN model and targeted signalling pathways downstream of ICs‐mediated interaction, which is a novel immunomodulatory strategy. Further development of Tris DBA as a therapeutic candidate for IgAN is warranted.
circRNA 001306 enhances hepatocellular carcinoma growth by up‐regulating CDK16 expression via sponging miR‐584‐5p
Authors: Liu Qian , Wang Cixiao , Jiang Zeyou , Li Shan , Li Fang , Tan Hua‐Bing , Yue Su‐yang 
Published: November 2020

AbstractCircular RNAs (circRNAs) have been demonstrated to play important roles in cancer progress. However, the roles in hepatocellular carcinoma (HCC) are still unclear. Here, we found has_circRNA_001306 (circ_1306) was up‐regulated in HCC tissues and cell lines. Knockdown the expression circ_1306 significantly suppressed HCC cell proliferation and induced the cell apoptosis in vitro and in vivo. Furthermore, we identified circ_1306 could up‐regulate the expression of CDK16 by sponging miR‐584‐5p. The expression of miR‐584‐5p was decreased, and the expression of CDK16 was increased in HCC tissues and cell lines. Meanwhile, either knockdown of miR‐584‐5p or overexpression of CDK16 could suppress the HCC cell proliferation. In vivo, overexpression of miR‐584‐5p or knockdown of circ_1306 could inhibit the expression of CDK16, and suppress tumour growth. Altogether, our findings suggested that circ_1306 could promoter HCC progress by miR‐584‐5p/CDK16 axis, which provided a novel marker for HCC diagnosis and treatment.