bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anticoagulant Management and Synthesis of Hemostatic Proteins during Machine Preservation of Livers for Transplantation
Authors: Karangwa Shanice A. , Lisman Ton , Porte Robert J. 
Published: August 2020

AbstractLiver transplantation remains the only curative treatment for patients with end-stage liver disease. Despite a steadily increasing demand for suitable donor livers, the current pool of donor organs fails to meet this demand. To resolve this discrepancy, livers traditionally considered to be of suboptimal quality and function are increasingly utilized. These marginal livers, however, are less tolerant to the current standard cold preservation of donor organs. Therefore, alternative preservation methods have been sought and are progressively applied into clinical practice. Ex situ machine perfusion is a promising alternative preservation modality particularly for suboptimal donor livers as it provides the ability to resuscitate, recondition, and test the viability of an organ prior to transplantation. This review addresses the modalities of machine perfusion currently being applied, and particularly focuses on the hemostatic management employed during machine perfusion. We discuss the anticoagulant agents used, the variation in dosage, and administration, as well as the implications of perfusion for extended periods of time in terms of coagulation activation associated with production of coagulation factors during perfusion. Furthermore, in regard to viability testing of an organ prior to transplantation, we discuss the possibilities and limitations of utilizing the synthesis of liver-derived coagulation factors as potential viability markers.
Small business response to regulation: incorporating a behavioral perspective
Authors: Shapiro Stuart , Borie-Holtz Debra 
Published: August 2020

AbstractThe use of behavioral economics in policy-making and public administration has neglected the heuristics that affect those who must comply with regulations. These heuristics affect the decision to comply with a regulation, and therefore they affect the effectiveness of regulations, and more generally the attitude of the regulated community toward government. In a survey and in interviews, small business owners described their compliance activities and their attitudes toward government. The business owners demonstrated the availability heuristic in their hatred of paperwork requirements, the bandwagon effect in seeking out reinforcement of negative reactions toward regulation, the anchoring of attitudes in particularly unpleasant interactions with government, and the impact of their economic well-being on their reaction to regulation. They also demonstrated the ineffectiveness of some information disclosure requirements. Incorporation of these behaviors and heuristics into the evaluation and enforcement of regulation may improve compliance and business relations with regulatory agencies.
Science diplomacy of Poland
Authors: Szkarłat Monika 
Published: August 2020

AbstractScience diplomacy (SD) has recently gained unprecedented attention as a subject of both an academic enquiry and political discourse. Thus, states employ many efforts to conceptualise and implement their science diplomacy strategies. To date, the most advanced in this regard are the rich industrialized countries slowly followed by others, e.g., Central and Eastern European (CEE) countries like Poland. While science diplomacy of selected states is debated among practitioners and analysed empirically, these efforts do not include CEE countries. In this article we present the regulatory, institutional and operational frameworks of Polish science diplomacy. The opinions of SD stakeholders obtained in a series of interviews supplement the findings and give a wider perspective on the challenges Polish science diplomacy is facing. We argue that although a universal model of science diplomacy does not exist, states such as Poland may profit from the experience of more advanced systems. We also claim that Polish science diplomacy is currently significantly conditioned by the domestic political situation. This negatively impacts continuity and coordination in strategic programming and implementation of SD. The case of Poland is compared with two other countries—France and the Czech Republic.
Ligands of G-quadruplex nucleic acids
Authors: Andreeva Daria V. , Tikhomirov Alexander S. , Shchekotikhin Andrey E. 
Published: August 2020

The review summarizes advances in the development of low-molecular-weight ligands for G-quadruplex (G4) nucleic acid structures published in the past five years. Main chemical classes of these ligands (polyaromatic compounds, macrocyclic systems, metal complexes and heterocyclic derivatives) are considered. The chemical structures of the ligands and their influence on the stabilization of quadruplexes are analyzed. Future prospects of design of G4 ligands and their applications are discussed.
The bibliography includes 188 references.
Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary
Authors: Niu Wanbao , Spradling Allan C. 
Published: August 2020

SignificanceThis paper improves knowledge of the somatic and germ cells of the developing mouse ovary that assemble into ovarian follicles, by determining cellular gene expression, and tracing lineage relationships. The study covers the last week of fetal development through the first five days of postnatal development. During this time, many critically important processes take place, including sex determination, follicle assembly, and the initial events of meiosis. We report expression differences between pregranulosa cells of wave 1 follicles that function at puberty and wave 2 follicles that sustain fertility. These studies illuminate ovarian somatic cells and provide a resource to study the development, physiology, and evolutionary conservation of mammalian ovarian follicle formation.
Crystal structure of a glycoside hydrolase family 68 β-fructosyltransferase from Beijerinckia indica subsp. indica in complex with fructose
Authors: Tonozuka Takashi , Kitamura Junichi , Nagaya Mika , Kawai Reika , Nishikawa Atsushi , Hirano Katsuaki , Tamura Keisuke , Fujii Tadashi , Tochio Takumi 
Published: August 2020

Abstract
An enzyme belonging to glycoside hydrolase family 68 (GH68) from Beijerinckia indica subsp. indica NBRC 3744 was expressed in Escherichia coli. Biochemical characterization showed that the enzyme was identified to be a β-fructosyltransferase (BiBftA). Crystallization of a full-length BiBftA was initially attempted, but no crystals were obtained. We constructed a variant in which 5 residues (Pro199-Gly203) and 13 residues (Leu522-Gln534) in potentially flexible regions were deleted, and we successfully crystallized this variant BiBftA. BiBftA is composed of a five-bladed β-propeller fold as in other GH68 enzymes. The structure of BiBftA in complex with fructose unexpectedly indicated that one β-fructofuranose (β-Fruf) molecule and one β-fructopyranose molecule bind to the catalytic pocket. The orientation of β-Fruf at subsite −1 is tilted from the orientation observed in most GH68 enzymes, presenting a second structure of a GH68 enzyme in complex with the tilted binding mode of β-Fruf.
Inverse HuaLuogeng’s “Exception Set” Method
Authors: Zhou Mi , Liu Hairui 
Published: August 2020

Abstract
Hualuogeng for goldbach conjecture raised an exception collection methods: use a fraction value indicates the possibility of goldbach conjecture fails, take to infinity, the denominator fraction value infinite close to 0, come out a conclusion that goldbach conjecture is not set up the possibility of infinite close to 0. In this paper, the author USES the method of opposite to hualuogeng, with a score value indicates the possibility of goldbach conjecture was set up, the denominator is fixed, molecular ceaseless overlay, molecule is more and more big, such fraction value infinitely close to 1, thus it is concluded that the possibility of goldbach conjecture established infinitely close to 1.
Generalized uncertainty relations for semi-Markov processes
Authors: Vu Tan Van , Hasegawa Yoshihiko 
Published: August 2020

Abstract
The thermodynamic and kinetic uncertainty relations provide finite-time bounds on the observable fluctuation in Markov processes. Herein, we generalize these bounds for semi-Markov processes. Specifically, we prove that, unlike in the Markovian case, the fluctuation of time-antisymmetric observables is bounded not only by entropy production but also by a memory term. For generic observables, we analogously show that the fluctuation is bounded by both dynamical activity and a memory term. Our results indicate that memory plays an important role in the bounds. Interestingly, with a proper form of the waiting-time distribution, the memory can decrease the observable fluctuation. When the waiting-time distribution is Poissonian (i.e., the process becomes Markov), the memory terms vanish, and the derived bounds reduce to the conventional bounds.
Two Nonhomogeneous Boundary Value Problems for a Rectangle: Exact Solutions
Authors: Kerzhaev Alexander P 
Published: August 2020

Abstract
In the paper, for the first time we give exact solutions to two nonhomogeneous boundary value problems of the theory of elasticity for a rectangle with free long sides. Inside the rectangle there are applied two equal concentrated forces directed oppositely along the horizontal axis (even-symmetric deformation). The method of solution is based on the use of the solution to the biharmonic problem for a smooth semi-strip and the method of the integral Fourier transform. In the first problem, the short sides of the rectangle are free; in the second, they are rigidly clamped. The solutions to both problems are constructed on the superposition principle in the form of the sum of integrals and series in trigonometric functions and Papkovich–Fadle eigenfunctions. The coefficients of these expansions are determined by simple formulas as the Fourier integrals of given boundary functions.
The development of the LRnLA algorithm for cross stencil numerical schemes for the CUDA GPU model of parallelism
Authors: Perepelkina Anastasia , Levchenko Vadim 
Published: August 2020

Abstract
This document describes the recent progress in the constructing of a 3D and time (3D1T) spatial and temporal blocking algorithm for cross stencil numerical scheme implementation. This method serves the purpose of raising the operational intensity of the memory-bound problems and increasing the performance limit at least several times compared to the algorithm without temporal blocking. The method of construction of LRnLA algorithms involves choosing the prism shape that subdivides the dependency graph of the problem into a series of tasks with prescribed dependencies between each other. The algorithm is adjusted to the GPU architecture, taking into account all available levels of parallelism. The proposed algorithm had been implemented and called DiamondCandy. The obtained efficiency in our current implementation is 59% of the limit estimated by theoretical analysis.
The tissue as self-assembly of notochord with sequential linear programming
Authors: Wang Zhiren 
Published: August 2020

Abstract
Zebrafish serves as a model organism in morphogenesis studies in cell biology. One of the main difficulties of modeling a specific morphogenetic process come from the proper identification of its key features. To study the influence of geometric constraint in morphogenesis, here this article models the notochord as hard spheres assemble in an elliptical cylinder and optimize the packing density. This article implements linear approximation on the hard sphere constraints and find the optimal packing configuration by the sequential linear programming (SLP) method. During the process, this article modifies the SLP scheme into expanding the spheres in a fixed cylindrical confinement. This article finds the staircase and similar structures becomes predominant as increasing the ellipticity of the confinement. Our study deepens the understanding of the notochord morphogenesis, and also provides methodological guidance on related modeling studies involving geometric constraints.
The (2, m, 2, ∞, r)-Wizard of Houses
Authors: Prapaithrakul Tanayot , Trakultraipruk Nantapath 
Published: August 2020

Abstract
The (n, m, l, t, r)-Wizard of houses is a game played by n players p
1, p
2, p
3, …, pn
on a board with m houses. There are l colors of token, and t tokens for each color. Each player chooses one color from the l colors, so that each has a different color. Player p
1 starts the game by choosing one token of any color and putting it into any house. Players p
2, p
3, p
4, …, pn
follow suit, until one round is completed. The game is over when the rth
round ends or after the tokens are all played, whichever comes first. In each house, each player who has the highest number of his own colored tokens receives one point. The winner is the player who has the highest score. In this paper, we determine the (2, m, 2, ∞, r)-Wizard of houses. We provide non-losing strategies for both players.
Convergence of the linearized system for a compressible Navier-Stokes-Poission system
Authors: Dong Ying 
Published: August 2020

Abstract
In this paper, we are concerned with the limit for solutions of combining viscid and compressible isentropic Navier-Stokes-Poisson system in a bounded domain Ω ⊂ RN
, N ≥ 1, with Dirichlet boundary condition. We first derive Navier-Stokes-Poisson system by using Energetic Variational Approach. Then the convergence of the compressible isentropic Navier-Stokes-Poisson system to the linearized system is proven for the global weak solution and for the case of general initial data with satisfying appropriate conditions.
The Analysis of Solar Radio Burst Type III Associated with Solar Activities Due to Magnetic Reconnection from 2012-2017
Authors: Hamidi Z.S. , Shariff N.N.M. 
Published: August 2020

Abstract
Solar Radio Bursts Type III (SRBT III) and their correlation with solar flares always had been interesting issues. The objective of this research is to study the correlation of SRBT III related to solar flares to magnetic reconnection theory. The importance of this correlation is to enhance the understanding of the particles behaviour during the events over this burst. The data for both SRBT III can be obtained from the e - CALLISTO website. Meanwhile, the data for solar flares were obtained from the Solar Monitor website and Computer Aided CMEs Tracking website respectively. There are 44 data have been collected starting from 2012 until 2017. The Pearson Correlation Coefficient is a method used in obtaining the correlation of the variables of SRBT III and solar flares events. The value of R obtained for the peak flux and the starting frequency of SRBT III is +0.3364. The mean of the peak flux is 6.0 × 10−5W/m2 which is in the M group with a magnitude of 6.0. From this study, they found that the single SRBT III is due to the single magnetic reconnection whereas for the storm and group SRBT III is due to the multiple magnetic reconnections.
The steady states of dielectric particles with Quincke rotation under ion traps
Authors: Zhang J S 
Published: August 2020

Abstract
The dynamics of dielectric particles with Quincke rotation under nonuniform electric fields generated by ion traps are researched. Based on a recently proposed model, I make a further discussion about a quadrupole electric field with numerical simulation. According to the results, the steady state of a single particle under different field strength can be classified into several stages. Some more complicated electric fields are considered too. But the dynamics of particle under other multipole fields can’t be simulated well with the model, which indicates that the model still needs to be improved. A more complicated 3D electric fields are considered too, the evolution of steady states under this 3D electric field is similar to the quadrupole field.
Airbag Helmet: Design and Analysis of Helmet Piezoelectric Accelerometer
Authors: Lin Edward R. 
Published: August 2020

Abstract
The author invented an airbag helmet to provide effective protection for two-wheeled vehicle riders. This paper illustrates the desion and analysis of this Helmet Piezoelectric Accelerometer. Analysis is based on the finite element model of solid mechanics (e.g. linear elasticity and piezoelectricity) with a carefully selected software of COMSOL Multiphysics. Finite element analysis method helped the author to reduce the need for physical prototypes in design process. With a high degree of accuracy, the author modeled complex material physical deformations with detailed visualization and solved the problem. Equations were used for calculation during the process. This paper provides the design of comsol-based solid mechanics and piezoelectricity simulation and simulates the process of converting the mechanical vibration into voltage signals by using piezoceramics, so as to supply power to the airbag accelerometer and release the airbag in time. The reliability and safety of the design are verified by means of the mechanical and electrical simulation. In case of a traffic accident, the airbag will inflate instantly and form a balloon-shaped helmet wrapping the rider’s head to secure the head effectively.
Development and physico-chemical characterization of Polyvinylidene fluoride (PVDF) flat sheet membranes with antibacterial properties against E. coli and S. aureus
Authors: Escorial Jose Gabriel , Lanzanas Stephen Paolo , Berjamin Kirstine Joy , Caliolio Marielle Hannah , Dimaunahan Ericson , Lagura Vivian , Milo Lumen , Basilia Blessie 
Published: August 2020

Abstract
The use of silver-modified montmorillonite (Ag-MMT) nanoclay from local montmorillonite ore as an additive for the development of PVDF flat sheet membranes with antibacterial properties for use in water disinfection was the focus of this study. It covers the development of PVDF flat sheet membranes with Ag-MMT nanoclay. The physico-chemical characterization was done through XRD, AFM, contact angle measurement, and FE-SEM while the antibacterial properties against gram-positive S. aureus and gram-negative E. coli were through inhibition zone and contact inhibition assessment. XRD results showed exfoliation of the Ag-MMT nanoclay in the PVDF flat sheet membrane, with minimal intercalations and similar functional group interactions. AFM results showed an increased surface roughness for every increase in Ag-MMT nanoclay which correlates to the contact angle measurement of membranes, demonstrating high contact angle measurement and high hydrophobicity for rougher surfaces, showing high hydrophilicity for the 0.250% Ag-MMT nanoclay membrane with a contact angle of 79.5 degrees. FE-SEM results reveal the morphology of the membrane. All experimental membranes are negative in contact inhibition against E. coli and S. aureus. However, the Ag-MMT nanoclay has been found to have antibacterial properties with the formation of inhibition zones, showing a higher sensitivity against E. coli.
Framework to define environmental sustainability boundaries and a review of current approaches
Authors: Vea Eldbjørg Blikra , Ryberg Morten , Richardson Katherine , Z Hauschild Michael 
Published: August 2020

Abstract
Environmental sustainability boundaries can help us navigate a sustainable development trajectory, by evaluating environmental performance of current actions in relation to such boundaries. However, current definitions of environmental sustainability boundaries have shortcomings when used in environmental assessments. The shortcomings include considerations of regional differentiation and transparency with respect to how uncertainty is addressed. This paper seeks to improve the definition and application of environmental sustainability boundaries in environmental assessments by reviewing existing approaches to set them and elaborating an analytical framework for defining, communicating and adopting environmental sustainability boundaries in assessments. 110 original environmental sustainability boundaries were identified from existing literature and grouped into 13 categories of boundary approaches. The framework addresses five components (objective, boundary principle, uncertainty principle, accepted levels of impacts, and scientific estimate), and recommends practices for each. The framework is recommended for defining, communicating and adopting environmental sustainability boundaries, to facilitate a consistent application of them in environmental assessments. The analysis of existing boundary approaches showed that they often handle value-based aspects (e.g. choice of uncertainty principle) differently. Thus, it is recommended that value-based aspects are communicated explicitly to enable a practitioner to consider how this resonates with his/her own values or the values of central stakeholders when adopting environmental sustainability boundaries in an environmental assessment.
Utilization of Google Earth Engine (GEE) for land cover monitoring over Klang Valley, Malaysia
Authors: Wahap N.A , Shafri Helmi Z.M. 
Published: August 2020

Abstract
Geospatial Big Data is currently received overwhelming attention and are on highlight globally and Google Earth Engine (GEE) is currently the hot pot platform to cater big data processing for Remote Sensing and GIS. Currently few or no study regarding the usage of this platform to study land use/cover changes over years in Malaysia. The objective is to evaluate the feasibility of GEE as a free cloud-based platform by performing classification of Klang Valley area from Landsat composites of three different years (1988-2003-2018) using multiple Machine Learning Algorithms (MLA). The best classification results were then imported and further processed to quantify the changes over the years using commercial software. Although, the classification results are of high accuracy but CART shows the best accuracy with 94.71%, 97.72% and 96.57% in 1988, 2003 and 2018 in comparison with RF and SVM. Some misclassified pixels were encountered because the annual composited images were compiled without taken into considerations of crops phenological stages (paddy) which resulted to the misclassified agricultural land into urban and bare land. Hence, the selection and composition of data initially had to be structured and strategized prior to processing as they can affect the classification result and further analysis. Regardless, GEE has performed quite well and fast in term of time and processing complexity of multiple datasets with minimal human interaction and intervention. Generally, GEE has proven to be reliable in fulfilling the objectives of this study to evaluate the GEE feasibility by performing classification and quantifying the land use/cover of studied area and provide good base for further analysis using different platform.