bluuebunny/crossref_metadata_2025_split huggingface dataset:
Forecasting of the safety hazards to aviation and marine operations in some area of water with active volcanic activities
Authors: Куклев Е.А. , Петухов Г.М. 
Published: June 2020

В статье авторы рассматривают проблему обеспечения безопасности полетов и мореплаванья в прибрежных районах Тихоокеанского огненного кольца, как наиболее опасного региона мира по активности и влияния вулканической деятельности на транспортную инфраструктуру стран Азиатско-Тихоокеанского региона. Предлагают принципы ранжирования значимости угроз нарушения условий нормального функционирования транспортных средств в зонах активной вулканической деятельности вследствие воздействия на эти средства продуктов вулканического извержения (пепел с разной дисперсностью, вулканические бомбы, пирокластические и грязевые потоки, цунами, излияние лавы, ядовитые газопаровые продукты извержения остывающей кальдеры и пр.) в зависимости от дистанции до источника вулканизма с момента времени начала его активности. Предложено использовать международные стандарты и классификаторы опасности вулканических процессов при планировании конфигураций транспортных потоков в бизнес-процессах международных перевозок пассажиров и грузов морскими и воздушными судами в периоды эксплозивных извержений вулканов Тихоокеанского огненного кольца.
In the article the authors consider the problem of ensuring safety of navigation in the coastal regions of the Pacific ring of fire as the most dangerous region in the world according to the activity and influence of volcanic activity on the transport infrastructure of the Asia-Pacific region. The authors propose principles for ranking the significance of threats to the normal functioning of vehicles in areas of active volcanic activity due to the impact of volcanic eruption products on these vehicles (ash with different dispersal, volcanic bombs, pyroclastic and mud flows, tsunamis, lava outpouring, poisonous gas-vapor products of an eruption of a cooling Caldera, etc.,) depending on the distance to the source of volcanism from the time of its beginning of activity. It is proposed to use international standards and hazard classifiers for volcanic processes when planning traffic flow configurations in the business processes of international transportation of passengers and cargo by sea and aircraft during periods of explosive eruptions of volcanoes of the Pacific Ring of Fire.
Nonlinear model of a dynamic system for forecasting of fuel consumption of a ship using a neural network
Authors: Филатов В.И. 
Published: June 2020

В современных условиях коммерческого судоходства, большое внимания уделяется вопросам оптимизации расхода топлива на судах. Наиболее критическим моментом, определяющим эффективность рейса, является количество бункерного топлива, использованного на морском переходе судном. В данной статье предложен подход к прогнозированию расхода топлива на предстоящем переходе судна с помощью использования нейронной сети, обученной с помощью алгоритма Левенберга-Марквардта, а также рассмотрено преимущество данного метода в сравнении с методами других исследователей. Статистическая выборка для машинного обучения составлена на основе эксплуатационных данных с танкера класса Афрамакс . Элементом новизны в данной работе является формирование данных для обучающего множества, а также возможность нелинейного прогнозирования посуточного приращения скорости. Данный метод имеет высокую точность и может применятся как фрахтователем, так и судоводителем для того, чтобы оценить экономическую эффективность предстающего рейса или выбрать оптимальный маршрут по параметру расхода топлива. Ещё одной задачей прогнозирования параметров судна на переходе с помощью нейронной сети является расчёт ожидаемых приращений скорости судна, что таблица расходов бункерного топлива может быть применена только при условиях не более 4-5 баллом во шкале Бофорта.
In modern conditions of commercial shipping, much attention is paid to the optimization of fuel consumption on the sea. The most critical moment determining the voyages efficiency is the amount of bunker fuel used by the ship at the sea passage. This article proposes an approach to forecasting fuel consumption at the upcoming passage of a vessel using a neural network taught-in by the Levenberg-Marquardt algorithm, and also considers the advantage of this method in comparison with methods of other researchers. The statistical sample for machine learning is based on operational data from an Aframax class tanker. The novelty element in this work is the formation of data for the training set, as well as the possibility of nonlinear forecasting of the daily increment of speed. This method is highly accurate and can be used by both the charterer and the navigator in order to evaluate the economic efficiency of the upcoming voyage or to choose the optimal route according to the fuel consumption parameter. Another task of predicting the parameters of a vessel at a passage using a neural network is to calculate the expected increments of the vessels speed, with that the table of bunker fuel consumption can be applied only under conditions of no more than 4-5 points on the Beaufort scale.
El cauce mítico dionisiaco presente en los festivales de música electrónica
Authors: Aguilar Campos Citlaly 
Published: June 2020

El ser humano vive y comprende a través de narrativas, el mito es una de ellas ya que funge un papel fundamental en la estructura de nuestro conocimiento. Los mitos prevalecen hasta nuestros días y adquieren nuevos sentidos acorde a la época sociohistórica. A este fenómeno, el antropólogo francés Gilbert Durand lo denomina como cauce mítico.
Uno de estos cauces es el de Dioniso, quien simboliza el vino, la abundancia, el paroxismo salvaje. Desde la década de los 60 con la contracultura y la ruptura de paradigmas, la sociedad se ha volcado en una vorágine de apertura a los tabúes, desencantamiento ante el progreso y cuestionamiento crítico de lo hegemónico. Una de la expresiones artísticas derivadas de esta corriente han sido los festivales de música, los cuales han permitido unir a diferentes generaciones en un espacio común.
Entre estos eventos, destacan los del género electrónico, tales como Tomorrowland, Electric Daisy Carnival (EDC) y Burning Man que -sin ser su principal objetivo- han perpetuado el cauce mítico dionisiaco al fomentar una atmósfera festiva, extática y de espíritu colectivista, siendo tal afirmación la hipótesis a develar a través de los postulados hermenéuticos de G. Durand, M. Beuchot y Rollo May
Cysts and parasites in an abattoir in Northwest Ethiopia; an urgent call for action on “one health”
Authors: Getahun Desalegn , Van Henten Saskia , Abera Adugna , Senkoro Mbazi , Owiti Philip , Lombamo Fantu , Girma Blen , Ashenefe Baye , Deressa Asefa , Diro Ermias 
Published: June 2020

Introduction: Zoonotic parasitic infections such as echinococcosis affect cattle, sheep and goats by lowering quality of meat and hides as well as decreasing milk production. The burden of such diseases among humans is usually underestimated as they are difficult to diagnose. We used abattoir data to estimate the prevalence of zoonotic parasitic infections in animals.
Methodology: Data from 2005-2018 was used from the registry of an abattoir in Northwest Ethiopia. Frequencies, proportions and trends over time were analyzed. Meat inspection was conducted by visualization, palpation and incision.
Results: A total of 58,787 animals were slaughtered in the abattoir during the study period. These included 51,956 (88 %) cattle, 5,890 (10%) sheep and 941 (2%) goats. The detected parasites included Echinococcus in 12,334/58,787 (21%) and Fasciola in 10,551/58,787 (18%) animals. Echinococcus infection was highest among goats (267/941, 28%), followed by cattle (11,591/51,956, 22%) and sheep (476/5,890, 8%). Fasciolosis was detected in 9,877/51,956 (19%) cattle and 178/941 (19%) goats. The number of animals slaughtered strongly decreased over time from 8,405 in 2006 to 1,605 in 2018. However, the proportion of parasitic infections remained high with some fluctuations over the study period.
Conclusions: Echinococcosis and fasciolosis were very common with one out of five animals slaughtered infected. This is of public health concern and needs urgent multi-sectorial efforts from stakeholders at the national and regional level for control of these diseases. One health program approaches may warrant the control of transmission to humans.
Clinical features and treatment outcomes of visceral leishmaniasis patients admitted to three centers in Oromia, Ethiopia
Authors: Tekalign Samson , Adera Cherinet , Den Boer Margriet , Miecha Hirpha , Zewde Ashenafi , Mulugeta Dagnachew , Bishawu Tesfahun , Birru Weyuma , Lema Awoke , Sahlu Tilahun , Alves Fabiana , Manzi Marcel , Takarinda Kudakwashe , Van Griensven Johan 
Published: June 2020

Introduction: In three health care facilities in the Oromia region, the aim of this study is to report on 1) the number of VL cases registered over time (2013-2018) and 2) the clinical profile, type of treatment used and response to treatment.
Methodology: A retrospective cohort study was conducted among all VL cases admitted with a diagnosis of VL.
Results: A total of 434 VL cases were registered at the three health facilities, but patient files were available for only 188. Most (51.6%) were children and only three presented with VL relapse. 78 (41.5%) of the 188 patients presented within one month of symptom onset. Concurrent severe acute malnutrition (27.1%), tuberculosis (6.4%) and malaria (6.4%) were common. There were only two cases with HIV coinfection. Fourty-three percent were treated with antimonials, 34% with antimonials combined with paromomycin and 23% with AmBisome. Amongst the 188 patients with patient files there were no deaths and one treatment failure. Six months outcome data were however missing for all. Aggregated data from the 434 VL cases reported three deaths, two treatment failures and one relapse.
Conclusions: Children were most commonly affected, suggesting long-term endemicity. While short-term outcomes are encouraging, long-term follow-up data are required.
Student Success Centers in Nursing Education: A Case Study Example
Authors: Byrd David A. , Meling Vanessa Bográn 
Published: June 2020

Background:
A student success center was established at an academic health science center in an effort to address student performance in a diverse undergraduate nursing program.

Method:
A process for determining student needs and narrowly tailored support interventions was determined through a modified Delphi focus group of students enrolled in a Hispanic Serving Institution's undergraduate nursing program.

Results:

Findings of this study are presented along with the 5-year outcomes associated with the center's efforts. Implementation of these narrowly tailored interventions has led to a considerable improvement in student engagement, as well as higher first-time pass rates on the NCLEX-RN
®
examination by graduates.

Conclusion:

To address the critical shortage of diverse nurses in the United States, schools of nursing must provide all necessary support mechanisms to ensure underrepresented and first-generation college students have every opportunity to graduate and enter the nursing workforce.

[
J Nurs Educ
. 2020;59(7):396–399.]
Enhanced Expression of Catalase in Mitochondria Modulates NF-κB–Dependent Lung Inflammation through Alteration of Metabolic Activity in Macrophages
Authors: Han Wei , Fessel Joshua P. , Sherrill Taylor , Kocurek Emily G. , Yull Fiona E. , Blackwell Timothy S. 
Published: June 2020

Abstract
NF-κB is a reduction-oxidation–sensitive transcription factor that plays a key role in regulating the immune response. In these studies, we intended to investigate the role of mitochondrial-derived reactive oxygen species in regulating NF-κB activation by studying transgenic mice that overexpress mitochondrial-targeted human catalase (mCAT). We treated wild-type (WT) and mCAT mice with intratracheal instillation of Escherichia coli LPS and found that mCAT mice had exaggerated NF-κB activation in the lungs, increased neutrophilic alveolitis, and greater lung inflammation/injury compared with WT mice. Additional studies using bone marrow chimeras revealed that this hyperinflammatory phenotype was mediated by immune/inflammatory cells. Mechanistic studies using bone marrow–derived macrophages (BMDMs) showed that LPS treatment induced a sustained increase in NF-κB activation and expression of NF-κB–dependent inflammatory mediators in mCAT BMDMs compared with WT BMDMs. Further investigations showed that cytoplasmic, but not mitochondrial, hydrogen peroxide levels were reduced in LPS-treated mCAT BMDMs. However, mCAT macrophages exhibited increased glycolytic and oxidative metabolism, coupled with increased ATP production and an increased intracellular NADH/NAD+ ratio compared with BMDMs from WT mice. Treatment of BMDMs with lactate increased the intracellular NADH/NAD+ ratio and upregulated NF-κB activation after LPS treatment, whereas treatment with a potent inhibitor of the mitochondrial pyruvate carrier (UK5099) decreased the NADH/NAD+ ratio and reduced NF-κB activation. Taken together, these findings point to an increased availability of reducing equivalents in the form of NADH as an important mechanism by which metabolic activity modulates inflammatory signaling through the NF-κB pathway.
Clinical Trials Facing “Serious Adverse Events” during the Ongoing COVID-19 Pandemic
Authors: Parikh Purvish M , Mehta Prashant , MVT Krishna Kumar , Babu K Govind 
Published: June 2020

Abstract
Aims and Objectives: The ongoing COVID-19 pandemic is having a profound impact on the current clinical trials. We wanted to document the extent of the disruption amongst Indian clinical trial sites. Materials and Methods: We conducted an online survey among oncologists in India with active trials to document their experience with challenges and novel solutions. Results: A total of 60 oncologists replied of which 40 had ongoing trials with open recruitment. Majority of them had stopped screening (55%) and recruitment (62.5%). Almost half of the sites did not have adequate infrastructure (47.5%). Almost all the sites had enrolled patients worried about the impact of COVID-19 on their health outcome (up to 87.5%). The majority of sites had problems with adherence to study schedule of events (87.5%) and administration of study medication (42.5%). A total of 55% of the sites had provided the option of virtual visits. Both investigators (75%) and sponsors/contract research organizations (67.5%) had reached out to each other to maintain study integrity. More than half the centers had difficulty related to adverse events and serious adverse events (documentation and reporting; up to 75%). Discussion: Regulatory authorities in several countries have announced guidelines on the conduct of clinical trials during the COVID-19 pandemic. Whether the disruption lasts for a short or long time, its impact on clinical trials is going to be irreparable.
Pembrolizumab: The Nut Cracker
Authors: Selvarajan Gangothri 
Published: June 2020

AbstractAnti-programmed cell death-1 (PD-1)/PD ligand-1 immune checkpoint inhibitors (ICIs) are the newest class of drugs approved for various advanced cancers. Pembrolizumab, an anti-PD1 inhibitor, is approved for treating advanced-stage solid malignancies and refractory lymphomas. Recently, it has been approved as tumor agnostic therapy for microsatellite instability-high advanced-stage disease. In all these studies, pembrolizumab has shown dramatic efficacy with lesser Grade3/4 immune-related adverse events. Contemporarily, immunotherapy paved the way for diagnostic assays and immunotherapy-related response assessment criteria definitions. No published Indian experience with ICIs exists other than isolated case reports. This article aims to review on pembrolizumab mechanism, its indications, and safety. The description of other ICIs is beyond the scope of this review.
The role and place of secondary vocational education in the system of transport education
Authors: Vasiliev A. S. , Razinkin N. E. 
Published: June 2020

Secondary vocational education is part of the state system of vocational education in the Russian Federation, which provides training for skilled workers and employees, mid-level specialists. It is these personnel, along with engineers, who are currently most needed both for the development and competitiveness of the transport industry, and for the Russian economy as a whole.The processes of restructuring the educational space of secondary vocational education in the framework of the implementation of the strategic goals of the development of the transport system of the Russian Federation are considered. The possibilities of the WorldSkills (WS) movement for the innovative development of secondary vocational education are analyzed; advantages and contradictions of the participation of educational organizations in national projects. An active role in the development of the WS movement of the Nonprofit Organization “Association of Colleges and Technical Schools of Transport” is shown.The author’s view on the possible solutions to the problems identified during the study is given.
Measures to reduce the downtime of a transit wagon with processing
Authors: Grishkova D. Yu. 
Published: June 2020

The program for the development of marshalling yards until 2025 assumes the concentration of car traffic processing at large, technically well-equipped marshalling yards. Measures to reduce the downtime of transit cars with processing at the marshalling yard A, aimed at identifying and reducing costs when driving freight trains of increased weight and length on the section A–I1, are relevant from a practical point of view.One way to reduce the cost of driving freight trains of increased weight and length is to avoid forming 9,000-ton trains. Station A forms trains of increased mass and length, measuring 8000 tons and 9000 tons. This technology has a certain positive effect — an increase in the average weight of the train by 25.5 tons, reducing the need for locomotives and locomotive crews, increasing the carrying capacity of the section, unloading the tracks of the receiving and sending fleet. Also, this technology entails a certain number of difficulties in operation, such as certain requirements for the equipment of locomotives and the use of only three-section locomotives for trains weighing 9,000 tons. This raises the question of the feasibility of driving trains weighing 9,000 tons.
TÜRKİYE’DE TÜKETİCİ KREDİLERİNİN CARİ İŞLEMLER AÇIĞI ÜZERİNDEKİ ETKİSİ: ARDL SINIR TESTİ YAKLAŞIMI
Authors: KILIÇ Jiyan , YÜKSEL Aliye 
Published: June 2020

Bu çalışmada Türkiye’deki tüketici kredilerinin cari işlemler açığı üzerindeki etkisi 2003 - 2018 yılları arasında araştırılması amaçlanmıştır. Analizde yer alan değişkenler cari açık, taşıt kredisi, konut kredisi ve diğer krediler olup, değişkenlere ait veriler aylık zaman serileri olarak ele alınmıştır. Analizde değişkenlere ait durağanlık tespiti ADF ve PP birim kök testleri ile gerçekleştirilmiştir. Seriler arasındaki eşbütünleşmenin varlığı ise ARDL Sınır Testi yardımıyla tespit edilmiş ayrıca değişkenler arasındaki kısa ve uzun dönemli ilişkinin ortaya konması amacıyla Wald testi uygulanmıştır. Elde edilen bulgulara göre; değişkenler arasında uzun dönem nedensellik ilişkisinin tespitinin yanı sıra bağımsız değişken olarak alınan her bir tüketici kredisinin cari işlemler üzerinde kısa dönemde nedensellik ilişkisi saptanmıştır. Ayrıca değişkenler arasında pozitif yönde bir ilişkinin varlığı tespit edilerek, tüketici kredileri hacmindeki bir artışın cari açığı arttırıcı bir faktör olduğu sonucuna ulaşılmıştır.
Special Force
Authors: MacKenzie Alastair 
Published: June 2020

The exploits of the British Army's elite 22nd Special Air Service Regiment - the regiment of the SAS that forms part of the Regular army - are shrouded in mystery and myths abound about its members. But what is the truth behind the public facade of clinical professionalism? How has such a small regiment attracted so many weighty legends? And what is the purpose of the SAS in the 21st century? "Special Force" provides an original and unusually critical overview of the activities of the SAS from the Malayan Emergency of 1950 to the present day. In the context of a detailed and often controversial analysis of the post-war activities of the Regiment, MacKenzie establishes that the Regiment's almost legendary professional competence is often not backed up by reality. Far from being part of a structured deployment of strategic military assets, MacKenzie argues that the use of the SAS in recent years has been primarily driven by the 'entrepreneurial' actions of a few SAS commanding officers. "Special Force" not only offers a revelatory history of the SAS in the modern period, it is also a disturbing expose of the truth behind the myth.
It will be essential reading for anyone with an interest in the British military - past, present and future.
Busks, Basques and Brush-Braid
Authors: Inder Pam 
Published: June 2020

The dressmaking trade developed rapidly during the 18th and 19th centuries, changing the lives of thousands of British workers. Busks, Basques and Brush-Braid focuses on the trade and the people within it, from their working conditions and earnings to their training, services and relationships with customers.
Exploring the lives of dressmakers in fact and fiction, the book looks at representations of the trade in the plays and novels of the time, while surveying the often harsh realities of the workers’ lives. From the arrival of the sewing machine to the influence of the department store, it explores the impact of mechanization, commercialization and modernity on a historical trade. Pamela Inder illuminates a new world of dressmaking enabled by goods like paper patterns and magazines, and sets out to investigate the increasing monopoly of female dressmakers in an industry once dominated by male tailors.
Drawing on a range of original and hitherto unpublished sources – including business records, diaries, letters, bills and newspaper articles – Busks, Basques and Brush-Braid reveals the untold story of the dressmaking trade. Beautifully illustrated with over 80 images, the book brings dressmakers into focus as real people, granting new insights into working class life in 18th- and 19th-century Britain.