bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative MRI for newly diagnosed supratentorial glioblastoma: a multicenter-registry comparative study to conventional surgery
Authors: Shah Amar S. , Sylvester Peter T. , Yahanda Alexander T. , Vellimana Ananth K. , Dunn Gavin P. , Evans John , Rich Keith M. , Dowling Joshua L. , Leuthardt Eric C. , Dacey Ralph G. , Kim Albert H. , Grubb Robert L. , Zipfel Gregory J. , Oswood Mark , Jensen Randy L. , Sutherland Garnette R. , Cahill Daniel P. , Abram Steven R. , Honeycutt John , Shah Mitesh , Tao Yu , Chicoine Michael R. 
Published: October 2020

OBJECTIVE
Intraoperative MRI (iMRI) is used in the surgical treatment of glioblastoma, with uncertain effects on outcomes. The authors evaluated the impact of iMRI on extent of resection (EOR) and overall survival (OS) while controlling for other known and suspected predictors.

METHODS
A multicenter retrospective cohort of 640 adult patients with newly diagnosed supratentorial glioblastoma who underwent resection was evaluated. iMRI was performed in 332/640 cases (51.9%). Reviews of MRI features and tumor volumetric analysis were performed on a subsample of cases (n = 286; 110 non-iMRI, 176 iMRI) from a single institution.

RESULTS
The median age was 60.0 years (mean 58.5 years, range 20.5–86.3 years). The median OS was 17.0 months (95% CI 15.6–18.4 months). Gross-total resection (GTR) was achieved in 403/640 cases (63.0%). Kaplan-Meier analysis of 286 cases with volumetric analysis for EOR (grouped into 100%, 95%–99%, 80%–94%, and 50%–79%) showed longer OS for 100% EOR compared to all other groups (p < 0.01). Additional resection after iMRI was performed in 104/122 cases (85.2%) with initial subtotal resection (STR), leading to a 6.3% mean increase in EOR and a 2.2-cm3 mean decrease in tumor volume. For iMRI cases with volumetric analysis, the GTR rate increased from 54/176 (30.7%) on iMRI to 126/176 (71.5%) postoperatively. The EOR was significantly higher in the iMRI group for intended GTR and STR groups (p = 0.02 and p < 0.01, respectively). Predictors of GTR on multivariate logistic regression included iMRI use and intended GTR. Predictors of shorter OS on multivariate Cox regression included older age, STR, isocitrate dehydrogenase 1 (IDH1) wild type, no O
6-methylguanine DNA methyltransferase (MGMT) methylation, and no Stupp therapy. iMRI was a significant predictor of OS on univariate (HR 0.82, 95% CI 0.69–0.98; p = 0.03) but not multivariate analyses. Use of iMRI was not associated with an increased rate of new permanent neurological deficits.

CONCLUSIONS
GTR increased OS for patients with newly diagnosed glioblastoma after adjusting for other prognostic factors. iMRI increased EOR and GTR rate and was a significant predictor of GTR on multivariate analysis; however, iMRI was not an independent predictor of OS. Additional supporting evidence is needed to determine the clinical benefit of iMRI in the management of glioblastoma.
The interaction between parental concern and socioeconomic status in pediatric hydrocephalus management
Authors: Reynolds Rebecca A. , Dixon Makayla , Gannon Stephen , CCRP  , Zhao Shilin , Bonfield Christopher M. , Naftel Robert P. , Wellons John C. , Shannon Chevis N. 
Published: October 2020

OBJECTIVEParent or guardian involvement is implicit in the care of pediatric patients with hydrocephalus. Some parents and guardians are more engaged than others. The relationship between socioeconomic status (SES), the level of parental concern about their child’s hydrocephalus management and future, and overall health status has not been clearly delineated. In this study, the authors sought to clarify this connection using hydrocephalus patient-reported health outcomes.METHODSThis cross-sectional study included children with surgically managed hydrocephalus whose parent or guardian completed the validated Hydrocephalus Outcome Questionnaire (HOQ) and Hydrocephalus Concern Questionnaire for parents (HCQ-P) on a return visit to the pediatric neurosurgery clinic at Vanderbilt University Medical Center between 2016 and 2018. Patients were excluded if the questionnaires were not completed in full. The calculated Overall Health Score (OHS) was used to represent the child’s global physical, emotional, cognitive, and social health. The HCQ-P was used to assess parental concern about their child. Type of insurance was a proxy for SES.RESULTSThe HOQ and HCQ-P were administered and completed in full by 170 patient families. In the cohort, 91% of patients (n = 155) had shunt-treated hydrocephalus, and the remaining patients had undergone endoscopic third ventriculostomy. The mean (± SD) patient age was 12 ± 4 years. Half of the patients were male (n = 90, 53%), and most were Caucasian (n = 134, 79%). One in four patients lived in single-parent homes or with a designated guardian (n = 45, 26%). Public insurance and self-pay accounted for 38% of patients (n = 64), while the remaining 62% had private or military insurance. In general, parents with higher concern about their child’s medical condition indicated that their son or daughter had a higher OHS (χ2 = 17.07, p < 0.001). Patients in families with a lower SES did not have different OHSs from those with a higher SES (χ2 = 3.53, p = 0.06). However, parents with a lower SES were more worried about management of their child’s hydrocephalus and their child’s future success (χ2 = 11.49, p < 0.001). In general, parents were not preoccupied with one particular aspect of their child’s hydrocephalus management.CONCLUSIONSMore engaged parents, regardless of their family’s SES, reported a better OHS for their child. Parents with public or self-paid insurance were more likely to report higher concern about their child’s hydrocephalus and future, but this was not associated with a difference in their child’s current health status.
A single-center retrospective analysis of 3- or 4-level anterior cervical discectomy and fusion: surgical outcomes in 66 patients
Authors: McClure Jesse J. , Desai Bhargav D. , Shabo Leah M. , Buell Thomas J. , Yen Chun-Po , Smith Justin S. , Shaffrey Christopher I. , Shaffrey Mark E. , Buchholz Avery L. 
Published: October 2020

OBJECTIVEAnterior cervical discectomy and fusion (ACDF) is a safe and effective intervention to treat cervical spine pathology. Although these were originally performed as single-level procedures, multilevel ACDF has been performed for patients with extensive degenerative disc disease. To date, there is a paucity of data regarding outcomes related to ACDFs of 3 or more levels. The purpose of this study was to compare surgical outcomes of 3- and 4-level ACDF procedures.METHODSThe authors performed a retrospective chart review of patients who underwent 3- and 4-level ACDF at the University of Virginia Health System between January 2010 and December 2017. In patients meeting the inclusion/exclusion criteria, demographics, fusion rates, time to fusion, and reoperation rates were evaluated. Fusion was determined by < 1 mm of change in interspinous distance between individual fused vertebrae on lateral flexion/extension radiographs and lack of radiolucency between the grafts and vertebral bodies. Any procedure requiring a surgical revision was considered a failure.RESULTSSixty-six patients (47 with 3-level and 19 with 4-level ACDFs) met the inclusion/exclusion criteria of having at least one lateral flexion/extension radiograph series ≥ 12 months after surgery. Seventy percent of 3-level patients and 68% of 4-level patients had ≥ 24 months of follow-up. Ninety-four percent of 3-level patients and 100% of 4-level patients achieved radiographic fusion for at least 1 surgical level. Eighty-eight percent and 82% of 3- and 4-level patients achieved fusion at C3–4; 85% and 89% of 3- and 4-level patients achieved fusion at C4–5; 68% and 89% of 3- and 4-level patients achieved fusion at C5–6; 44% and 42% of 3- and 4-level patients achieved fusion at C6–7; and no patients achieved fusion at C7–T1. Time to fusion was not significantly different between levels. Revision was required in 6.4% of patients with 3-level and in 16% of patients with 4-level ACDF. The mean time to revision was 46.2 and 45.4 months for 3- and 4-level ACDF, respectively. The most common reason for revision was worsening of initial symptoms.CONCLUSIONSThe authors’ experience with long-segment anterior cervical fusions shows their fusion rates exceeding most of the reported fusion rates for similar procedures in the literature, with rates similar to those reported for short-segment ACDFs. Three-level and 4-level ACDF procedures are viable options for cervical spine pathology, and the authors’ analysis demonstrates an equivalent rate of fusion and time to fusion between 3- and 4-level surgeries.
Time Investment for Program Implementation to Manage Neuropsychiatric Symptoms: An Observational Longitudinal Study in In-Home and Residential Care Settings
Authors: Nakanishi Miharu , Niimura Junko , Ziylan Canan , Bakker Ton TJEM , Granvik Eva , Nägga Katarina , Shindo Yumi , Nishida Atsushi 
Published: October 2020

Background: There are no studies on how the same psychosocial dementia care program is adapted to both in-home and residential care settings. Objective: To evaluate the time investment required by professionals to implement a psychosocial dementia care program to manage neuropsychiatric symptoms. Methods: A prospective observational study design was used. The program consisted of 1) a one-day training course, 2) three interdisciplinary discussion meetings in five months, and 3) a web-based tool for the continued assessment of neuropsychiatric symptoms. Care professionals implemented the intervention in in-home (19 in-home care management agencies and 14 multiple in-home service providers) and residential care settings (19 group homes and eight nursing homes) in Japan from October 2019 to February 2020. The level of neuropsychiatric symptoms for the participants was evaluated using the Neuropsychiatric Inventory (NPI: 0–144). The time investment was reported by participating professionals. A total of 125 persons with dementia were included at baseline. Results: Neuropsychiatric symptoms were significantly decreased at the final follow-up in all types of providers (Cohen’s drm = 0.44–0.61). The mean (SD) time required for the five-month implementation was 417.9 (219.8) minutes. There was a mean (SD) decrease of 8.6 (14.0) points in the total NPI score among the 103 persons with completed interventions. The time investment was significantly lower in in-home care management agencies than in group homes, and lower in follow-ups than at baseline assessment. Conclusion: The program implementation may incur a substantial time investment regardless of setting. An additional benefit scheme to reward the time investment would be helpful to encourage implementation until the follow-ups.
Water Budgets for Florida Dairy Farms
Authors: Bray David R. , Bucklin Ray A. , Van Horn H. H. , Nordstedt Roger A. , Bottcher A. B. , Gallaher R. N. , Chambliss C. G. , Kidder G. 
Published: October 2020

Revised! Circular 1091, a 6-page fact sheet by D. R. Bray, R. A. Bucklin, H. H. Van Horn, , R. A. Nordstedt, A. B. Bottcher, R. N. Gallaher, C. G. Chambliss, and G. Kidder, provides estimates of amounts of water commonly used for various purposes so that water use budgets for dairy farms can be developed on a per-cow and total-farm basis. Includes references. Published by the UF Department of Animal Science, 2008.
[Correction: Originally published February 1993, reviewed in 2008.]
Retired from EDIS October 2020.
Evite Estos Alimentos Durante el Embarazo
Authors: Valentín-Oquendo Isabel 
Published: October 2020

Este documento es la Hojuela FCS752-Span, una serie del Departamento de Ciencias de la Familia, Juventud y Comunidad, Servicio de Extensión Cooperativa de Florida, Instituto de Alimentos y Ciencias Agrícolas, Universidad de Florida. Fecha de publicación: Julio, 2002.
https://edis.ifas.ufl.edu/fy532
Avoiding room light during night may stimulate immunity in COVID-19 patients by promoting melatonin production
Authors: Ahmed Murtada Ahmed 
Published: October 2020

COVID-19 is
one of the greatest health issues facing humankind for many decades; it emerged
in Wuhan, China, late in December 2019, and rapidly spread over the world
within the short period. This report emphasizes the potential hazards of
exposure to room light at night which affects the immunity of COVID-19 patients
by suppressing their melatonin, which is only released from the pineal gland at
night. Exposure to light at night is especially common in the hospital setting.
This may make the symptom worse for the hospitalized patients and the light at
night should not be ignored. Thus, I suggest that COVID-19 patients should
avoid light at night either by wearing eye masks or darkening the room to
enhance pineal melatonin synthesis and increase their serum melatonin levels.
Entendimento da COVID-19 sobre aspectos relacionados ao distanciamento social
Authors: Oliveira João Pedro Silva , Costa Allana Caroline Bonfim , Lopes Ellen Karollyne Santos , Silva Liosmar José da , Gomes Karoline Barbosa , Oliveira Samara dos Santos , Barros Rubens Pessoa de 
Published: October 2020

No atual cenário do século XXI, a humanidade enfrenta uma nova ameaça. um vírus titulado por Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), agente etiológico da COVID-19. Em tempos de pandemia, a utilização de websurveys configura-se como uma ótima estratégia para a coleta de dados primários. Esse trabalho teve como objetivo analisar a percepção de acadêmicos a respeito da pandemia da COVID-19. Este estudo foi desenvolvido no município de Arapiraca e teve como público-alvo alunos de graduação do Campus I, da Universidade Estadual de Alagoas. A pesquisa foi desenvolvida em 3 etapas, a primeira foi a construção de um formulário usando a plataforma Formulários Google Docs, a segunda consistiu na distribuição do questionário através de aplicativos de redes sociais (WhatsApp, Instagram) e ficou disponível para ser respondido por cinquenta e três dias. Na etapa três, os dados foram organizados em planilhas do programa Microsoft Excel. A pesquisa teve um total de sessenta e duas pessoas que responderam ao questionário. O público atingido pela pesquisa foi representando por cidadãos da zuna rural, com uma porcentagem de 28,6%, e urbana, com 71,4%, sendo todos Alagoanos. A maioria (90,3%) acreditava que o isolamento social compõe uma medida preventiva eficaz, na ausência da vacina. Esta pesquisa transversal procurou investigar informações importantes que poderiam auxiliar os pesquisadores e profissionais da saúde a desenvolverem medidas de conscientização baseadas no público alvo. Trabalhos como este, utilizando uma metodologia de coleta de dados alternativa é importante para mostrar que mesmo em distanciamento social é possível fazer ciência.
Ensino de História e a Educação do Campo. Um olhar a partir das imagens de si
Authors: Tamanini Paulo Augusto , Morais Ana Meyre de , Souza Maria do Socorro 
Published: October 2020

Este artigo tem o objetivo de relacionar os contextos do Ensino de História, na Educação do Campo, atravessados pela sensibilidade de um olhar fotográfico que se volta para si. Importa então observar nas imagens fotográficas as experiências dos professores e alunos em ambientes rurais. Este escrito vai ao encontro das memórias imagéticas de professores e comunidades que refletem a Educação contextualizada a partir de suas experiências, levando em conta três fotografias. O critério da escolha das imagens fotográficas se deu em razão de elas representarem o cotidiano de profissionais da Educação no contexto do Campo. No primeiro momento, tratamos da imagem como fonte de ambientação escolar onde se desenham as práticas educativas do campo ou zonas rurais. Já no segundo momento, abordamos duas imagens que exploram a vida no campo onde se inserem o cotidiano de professores e alunos. E por último, tratamos da Educação do Campo como modalidade educacional com seus desafios, persistências, resistências, superações e esperança pela concretização de uma educação de qualidade para todos. Como resultado, observamos que a Educação do Campo se mostra como uma modalidade de formação em consolidação em que as imagens de si e das realidades rurais se mostram possibilidades didáticas para um conhecimento das coisas do Campo.
ANALISIS SEMIOTIKA PUISI PESONA BATIK KARYA USWATUN KHASANAH SEBAGAI PENDEKATAN PEMAHAMAN MAKNA
Authors: Wedasuwari Ida Ayu Made , Rasna I Wayan 
Published: October 2020

This study aims to determine the analysis of cultural semiotics, sociosemiotic and structural semiotic of poem entitled Pesona Batik. The design of this research was qualitative descriptive research design. The data of this research was taken from a poem entitled Pesona Batik by Uswatun Khasanah. The data was collected through observation, note-taking and library research. Data analysis was performed by data reduction, data presentation, data verification and data interpetation. The meaning implied by the poem was analyzed by cultural semiotic theory. It was found that the cultural element was expressed deeply through the beauty of Batik depicted in the poem. In addition, through structural semiotic analysis, it was also found that words were arranged in the form of phrases and clauses which were easily to be understood. The word meaning found in this poem was more denotative and lexiconic.
Pelatihan Manajemen Usaha Untuk Meningkatkan Daya Saing Kepada Para Pelaku Usaha Industri Kecil Dan Menengah (UIKM) Keripik Talas Beneng Di Kampung Cinyurup Kecamatan Karangtanjung Kabupaten Pandeglang
Authors: Suhandi Suhandi , Jefri Ulfi 
Published: October 2020

ABSTRACT The majority of the residents of Cinyurup village are beneng taro farmers and entrepreneurs of beneng taro chips, but the management is still simple and is not managed systematically and well-planned, so that it cannot provide maximum results. The aim of this training is to increase competitiveness for the small and medium entrepreneurs of taro chips into independent small industries. The method of implementation is through : seminars of material delivery, discussion, practice, mentoring, monitoring and evaluation. The results of this training show that not all small and medium industrial entrepreneurs are taro beneng chips those in Cinyurup village who have not implemented business management, have not processed distribution permits, halal certificates, produced product innovations and online marketing, due to limited funds and human resources.
Key words: training, business management, competitiveness, UIKM

ABSTRAK
Mayoritas penduduk warga kampung Cinyurup adalah petani talas beneng dan pelaku usaha keripik talas beneng, akan tetapi pengelolaannya masih sederhana dan tidak di kelola dengan sistematis dan terencana dengan baik, sehingga belum bisa memberikan hasil yang maksimal. Tujuan dari pelatihan ini untuk meningkatkan daya saing kepada para pelaku usaha industri kecil dan menengah keripik talas beneng menuju industri kecil yang mandiri. Metode pelaksanaan melalui : seminar penyampaian materi, diskusi, praktek, pendampingan, monitoring dan evaluasi. Hasil dari pelatihan ini menunjukan belum semua para pelaku usaha industri kecil dan menengah keripik talas beneng yang ada di kampung Cinyurup yang belum menerapkan manajemen usaha, belum mengurus surat ijin edar, sertifikat halal, memproduksi inovasi produk dan pemasaran online, karena keterbatasan dana dan sumber daya manusia.
Kata kunci: pelatihan, manajemen usaha, daya saing, UIKM
Paradojas de ciudadanía y conflictos de género en la política pública argentina. La Política de Salud Sexual y Procreación Responsable
Authors: Levín Silvia 
Published: October 2020

El artículo analiza el alcance del vínculo jurídico político establecido entre Estado y ciudadanas desde las garantías reconocidas en los derechos humanos sexuales y reproductivos. Utilizando un enfoque complejo, que combina diferentes dimensiones de análisis, interesa mostrar cómo y porqué las decisiones sobre la naturaleza jurídica de estos derechos y sobre su regulación política producen efectos disímiles en ese campo: desarrollo, interferencia o limitaciones de ciudadanía. Nuestra argumentación principal refere al conficto político que desatan esas decisiones y a los fundamentos antagónicos de las posiciones que los registran como derechos sociales de salud o como derechos individuales de libertad. En esas opciones se involucran con distinta intensidad los componentes constitutivos de la ciudadanía: la autonomía, la libertad y la igualdad. La intención es señalar que tanto el derecho como la política y la teología al fijar las “reglas de juego” en la sociedad buscan disciplinar los intereses existentes regulando el conflicto.
En el comienzo de todo… Los orígenes constitutivos de la identidad kirchnerista durante el gobierno de Néstor Kirchner (2003-2007)
Authors: Funes Andrés N. 
Published: October 2020

El artículo se propone analizar la constitución de la identidad política kirchnerista durante el gobierno de Néstor Kirchner (2003-2007). La hipótesis que guía esta investigación señala que en el período 2003-2007 el kirchnerismo constituyó su identidad en –al menos– tres aspectos: I) elaboró una cesura respecto a un pasado oprobioso ligado a la última dictadura cívico-militar y a la década de los noventa, identificando, además, como sus antagonistas principales a las “corporaciones”; II) erigió la imagen del “pueblo” a partir de la interpelación a la ciudadanía y a los “perdedores” de la reformas neoliberales de los años noventa; III) apeló a festividades y celebraciones típicas del acervo de la tradición peronista, en consonancia con las vicisitudes de la coyuntura política. También buscó incorporardentro de su estructura política en formación al Partido Justicialista (PJ), a la Confederación General del Trabajo (CGT) y a la Central de Trabajadores de la Argentina (CTA), a los finesde dotarse de poder político. El análisis estará basado en discursos pertinentemente seleccionados de Kirchner durante su presidencia, notas periodísticas útiles para iluminar la coyuntura y, por último, bibliografía teórica.
La escenografía profesoral como vínculo: el ethos magistral en el discurso de Cristina Fernández de Kirchner (2007-2011)
Authors: Gindin Irene 
Published: October 2020

La presente publicación, resultado de nuestra tesis doctoral, pretende mostrar los resultados del análisis de los discursos pronunciados por la ex mandataria argentina, Cristina Fernández de Kirchner, durante su primera presidencia. Dicho análisis está centrado en la identificación de un tipo de ethos que atraviesa las alocuciones de CFK y que aquí denominamos como ethos magistral. En la caracterización de este ethos nos abocamos a identificar y describir las formas de polémica que el discurso presidencial despliega y los objetos discursivos asociados a ellas. De este modo, trabajamos acerca de cómo se nombra, interpela y descalifica al contradestinatario por excelencia del período: los discursos neoliberales. Este tipo de contradestinatario se caracteriza por funcionar de forma abarcativa, incluyendo tanto a los sectores cívicos y militares participantes del último golpe de Estado, como a los actores involucrados en la etapa menemista,las grandes corporaciones mediáticas y los sectores económicamente más poderosos del agro. De todos ellos nos ocuparemos aquí.