bluuebunny/crossref_metadata_2025_split huggingface dataset:
The association between oscillatory burst features and deviations during human working memory
Authors: Kavanaugh Brian C. , Vigne Megan M. , Thorpe Ryan , Legere Christopher , Acuff W. Luke , Vaughan Noah , Tirrell Eric , Haegens Saskia , Carpenter Linda L. , Jones Stephanie R. 
Published: December 2024

ABSTRACTOscillatory power across multiple frequency bands has been associated with distinct working memory (WM) processes. Recent research has shown that previous observations based on averaged power are driven by the presence of transient, oscillatory burst-like events, particularly within the alpha, beta, and gamma bands. However, the interplay between different burst events in human WM is not well understood. The current EEG study aimed to investigate the dynamics between alpha (8-12 Hz)/beta (15-29 Hz) and high frequency activity (HFA; 55-80 Hz) bursts in human WM, particularly burst features and error-related deviations during the encoding and maintenance of WM in healthy adults. Oscillatory burst features within the alpha, beta and HFA bands were examined at frontal and parietal electrodes in healthy young adults during a Sternberg working memory task. Averaged power dynamics were driven by oscillatory burst features, most consistently the burst rate and burst power. Alpha/beta and HFA bursts displayed complementary roles in WM processes, in that alpha and beta bursting decreased during encoding and increased during delay, while HFA bursting had the opposite pattern, i.e., increased during encoding and decreased during the delay. The parietal electrode exhibited faster and stronger variation in burst features across WM stages than the frontal electrode. Critically, weaker variation in burst dynamics across stages was associated with incorrect responses and impaired overall task performance. Together, these results indicate that successful human WM is dependent on the rise and fall interplay between alpha/beta and HFA bursts, with such burst dynamics reflecting a novel target for the development of treatment in clinical populations with WM deficits.
Metagenomic mining reveals novel viral histones in dsDNA viruses
Authors: Liu Yang , Hou Zhuru , Hao Wanshan , Cui Shaoqing , Wang Haibo , Liu Yue 
Published: December 2024

ABSTRACTThe compaction of genomic DNA into nucleosomes with the help of histones had long been considered as a fundamental feature exclusive to eukaryotic cells. However, it was recently shown that archaea and bacteria also encode histones. A complex picture has emerged with more recent discoveries of eukaryotic-like histones within one phylum of double-stranded DNA (dsDNA) viruses. Nevertheless, the extent to which other dsDNA viruses encode histones remains largely unexplored. Here we conducted a metagenomic survey of viral histones that were further clustered based on sequence and predicted structural similarities. We identified over 1,500 viral histones and histone-fold proteins, including previously undescribed proteins found in the viral classCaudoviricetes. Structural predictions andin vitroassays demonstrated that histone triplets (where three histone folds are fused) and singlets co-occurring in the same viral genome are capable of forming nucleosome-like particles. Beyond nucleosomal histone functions, our analysis revealed six types of structurally and functionally diverse viral histone-fold proteins, some of which do not have known structural or functional homologs. Altogether, our findings reveal a previously unrecognized diversity of viral histones in dsDNA viruses, expanding the known repertoire, structural diversity, and functional versatility of viral histones beyond nucleocytoplasmic large DNA viruses.HighlightsHistone triplets and singlets co-occurring in the same dsDNA viral genomes assemble into nucleosome-like particlesSix novel types of structurally and functionally distinct viral histone-fold proteins are identifiedThe presence of viral histones is significantly positively associated with proteins containing SNF2 chromatin remodeling domain found in viral genomes
Heparanase, a host gene that potently restricts retrovirus transcription
Authors: Waxman Brandon , Salka Kyle , Timilsina Uddhav , Umthong Supawadee , Shukla Deepak , Stavrou Spyridon 
Published: December 2024

AbstractHeparanase (HPSE) is a heterodimeric β-D-glucoronidase that is critical in mammalian cells for the enzymatic cleavage of membrane associated heparan sulfate moieties. Apart from its enzymatic function, HPSE has important non-enzymatic functions, which include transcriptional regulation, chromatin modification and modulation of various signaling pathways. Interestingly, whileHPSEis an interferon stimulated gene, past reports have shown that it has proviral properties for many different viruses, including Herpes Simplex Virus 1, as it assists virus release from infected cells. Yet any antiviral functions associated with HPSE have not been described. Here we show that HPSE utilizes a hitherto unknown mechanism to restrict retroviruses, by targeting the step of proviral transcription. Moreover, we demonstrate that HPSE blocks transcription initiation by targeting the SP1 transcription factor. Finally, we illustrate that the antiretroviral effect of HPSE is independent of its enzymatic activity. This report describes a novel antiviral mechanism utilized by HPSE to inhibit retrovirus infection.ImportanceHeparanase (HPSE) has emerged as an important factor that has proviral functions for a number of viruses including herpes simplex virus and hepatitis C virus, by assisting in virus egress. However, HPSE is an interferon stimulated gene and thus is a part of the host antiviral defense. Nothing is known about the antiviral functions of HPSE. Here, we examine in depth the role of HPSE during retrovirus infection using two retroviruses, human immunodeficiency virus type 1 (HIV-1) and murine leukemia virus (MLV). In this report, we show that mouse, but not human, HPSE blocks retrovirus infection by targeting provirus transcription. HPSE sequesters the SP-1 transcription factor away from the proviral promoter thereby inhibiting transcription inhibition. In conclusion, our findings identify a novel antiviral function of HPSE and its potential role as an inhibitor of zoonotic transmission of retroviruses.
A genomic resource for exploring bacterial-viral dynamics in seagrass ecosystems
Authors: Ettinger Cassandra L. , Stajich Jason E. 
Published: December 2024

AbstractBackgroundSeagrasses are globally distributed marine flowering plants that play foundational roles in coastal environments as ecosystem engineers. While research efforts have explored various aspects of seagrass-associated microbial communities, including describing the diversity of bacteria, fungi and microbial eukaryotes, little is known about viral diversity in these communities.ResultsTo begin to address this, we leveraged metagenomic sequencing data to generate a catalog of bacterial metagenome-assembled genomes (MAGs) and phage genomes from the leaves of the seagrass,Zostera marina. We expanded the robustness of this viral catalog by incorporating publicly available metagenomic data from seagrass ecosystems. The final MAG set represents 85 high-quality draft and 62 medium-quality draft bacterial genomes. While the viral catalog represents 354 medium-quality, high-quality, and complete viral genomes. Predicted auxiliary metabolic genes in the final viral catalog had putative annotations largely related to carbon utilization, suggesting a possible role for phage in carbon cycling in seagrass ecosystems.ConclusionsThese genomic resources provide initial insight into bacterial-viral interactions in seagrass meadows and are a foundation on which to further explore these critical interkingdom interactions. These catalogs highlight a possible role for viruses in carbon cycling in seagrass beds which may have important implications for blue carbon management and climate change mitigation.
Unveiling the power of employer branding: enhancing talent retention through organizational advocacy
Authors: Choudhary Shiwani , Joshi Richa 
Published: December 2024

PurposeThis study aims to explore the relationship between employer branding and talent retention, also examining the mediating role of organizational advocacy. Additionally, it investigates the moderating effect of supervisor support and coworker support in the connection between organizational advocacy and talent retention.Design/methodology/approachTo achieve the objectives, a cross-sectional survey with convenience sampling was used to collect data from employees in the IT sector. PLS-SEM modeling was then employed to conduct the analysis.FindingsThe study revealed that dimensions of employer branding positively influenced organizational advocacy, supporting talent retention. Moreover, the study observed a significant moderating effect of supervisor support and coworker support concerning organizational advocacy and talent retention.Practical implicationsThis study offers valuable insights for a wide range of IT professionals. The results emphasize the significance of employer branding in shaping organizational advocacy and talent retention. Additionally, the supportive attitude of supervisors and coworkers plays a crucial role in retaining talented employees within an organization. The study validates the connections between employer branding dimensions and key variables, aiding in the refinement of existing theories and the creation of new conceptual frameworks in organizational behavior and human resource management. These findings can help managers and practitioners improve employer branding to engage their workforce effectively.Originality/valueThe authors have advanced social exchange theory by studying the link between employer branding and talent retention. The paper highlights the uniqueness of their investigation, which explores how employer branding influences talent retention with a focus on organizational advocacy, influenced by the level of support from supervisors and coworkers. This study will be a valuable resource for future academia, revealing the significant impact of employer branding on organizational advocacy and talent retention.
How can a global icon become a local icon? A qualitative case study of the Taipei Performing Arts Centre
Authors: Goudsmit Inge 
Published: December 2024

PurposeThis study aims to redirect attention from the symbolic significance of global iconic architecture towards exploring its impact and significance within their situated urban context; seeking to unpack whether and how a “situated multiplicity” of residents collectively shape these structures into local icons through their embodied performance and active engagement, creating an “urban meaning” rather than symbolic meaning.Design/methodology/approachWe conducted an inductive empirical analysis of the Taipei Performing Arts Centre (TPAC), using a mixed-method iterative approach including 160 surveys, observational mapping, and 53 interviews with citizens and experts in the TPAC neighbourhood.FindingsThe spectacular image of a global icon can sometimes alienate citizens because of its design, and thus affect their embodied performance. However, we found divergent interpretations of iconicity, including residents who see economic, cultural and social benefits, and contributions to the internationalisation of local urban landscapes. Future aspirations for engagement with the TPAC are centred on the public plaza, highlighting the importance of prioritising public spaces in the design and operation of iconic buildings to foster community engagement and social interactions.Practical implicationsThe study’s findings have implications for policy makers, planners and architects seeking to embed global iconic buildings into neighbourhood planning initiatives.Originality/valueMinimal scholarly attention has been paid to citizens’ perspectives of iconic buildings. By addressing this gap, we contribute to a holistic perspective of how active and embodied practices shape the urban context and give it meaning. Furthermore, this study suggests practical ways in which such buildings can serve various populations.
Insights into food security: affordability perspectives from Bayesian belief network models
Authors: Qazi Abroon 
Published: December 2024

PurposeThis study investigates the dependencies between the Global Food Security Index (GFSI) and its affordability-related indicators using Bayesian belief network (BBN) models. The research also aims to prioritise these indicators within a probabilistic network setting.Design/methodology/approachThe research utilises BBN models to analyse data from 113 countries in 2022. Nine indicators related to food affordability, including income inequality, safety net programmes and trade freedom, are examined to understand their impact on food security. The methodology involves statistical modelling and analysis to identify critical factors influencing food security and to provide a comprehensive understanding of the global food affordability landscape.FindingsThe study reveals that income inequality, the presence and efficacy of safety net programmes and the degree of trade freedom are significant determinants of food affordability and overall food security outcomes. The analysis reveals marked disparities in performance across different countries, highlighting the need for context-specific interventions. The findings suggest that improving safety net programmes, implementing trade policy reforms and addressing income inequality are crucial for enhancing food affordability and security.Originality/valueThis research contributes to the literature by using BBN models to comprehensively analyse the relationship between the GFSI and affordability-related indicators. The study provides novel insights into how different socioeconomic factors influence food security across a diverse range of countries. The study offers actionable recommendations for policymakers to address food security challenges effectively, thereby supporting the development of more equitable and resilient food systems globally.
Analysis of the impact of human resources employees’ perceptions on the process of digital transformation
Authors: Stef Anda , Crișan Emil Lucian 
Published: December 2024

PurposeEmployees’ perceptions of digital transformation (DT) affect digital technology adoption and utilization. These attitudes, such as digital preparation or acceptance of digitization, are linked to personal and organisational resources. The goal is to assess employees’ impressions of (1) DT in general and (2) the organization’s DT efforts, focusing on how these efforts affect their field of activity and (3) their DT expectations.Design/methodology/approachUsing the Unified Theory of Acceptance and Use Technology (UTAUT), a model was built and examined from three perspectives: demographic characteristics, employee views of DT and organisational activities in DT. We used semi-structured interviews with ten international HR employees to validate the model.FindingsBecause the IT company we studied has several digital technologies, global HR departments, and varied organisational contexts, we started with “purposive sampling”. The principal findings offer the model an extensive understanding of how demographic characteristics, employees’ views of digital transformation (DT), and organisational DT activities affect digital technology uptake and use expectations.Originality/valueThis research may help companies plan for HR department digital technology installation and use. The approach can enable further research on digital technology uptake in businesses and practical ways to meet employee expectations.
Experimental investigation of the post-fire response of single-shear bolted lap joints
Authors: Chakar Sara , El Ghor Ahmad , Hantouche Elie 
Published: December 2024

PurposeThis study aims at investigating experimentally the behavior of single-shear bolted lap joints with N-bolts and X-bolts (XB) after exposure to fire temperatures.Design/methodology/approachSixteen single-bolted lap joints with M20 Grade 8.8 bolt are heated to various targeted temperatures ranging from 400 °C to 900 °C and subsequently cooled back to ambient temperature. Following the heating and cooling stages, the specimens are subjected to direct tension tests to determine the reduction in shear capacity and slip resistance of the lap joints. Post-fire reduction factors are estimated from the axial load–displacement curves to determine the residual strength of N-bolted and X-bolted lap joints after exposure to fire temperatures. These reduction factors are incorporated into Equation J3-1 of ANSI/AISC 360 (2022) for the design of simple bolted connections acting in shear after fire exposure.FindingsThe results show that X-bolted lap joints exhibit a larger reduction in bolt shear capacities compared to those with N-bolts. The shear strength of lap joints with N-bolts begins to degrade after exposure to 500 °C, reaching a maximum reduction in shear strength of 40% at 900 °C. Conversely, the strength of lap joints with XB starts to degrade after exposure to temperatures beyond 400 °C, reaching a maximum reduction in shear strength of 42% at 750 °C. The post-fire reduction factors computed in this study showed that XB reduction factors are more conservative than the N-bolts and those available in the literature.Practical implicationsThis study provides preliminary data for the development of design guidelines of bolted connections with N-bolts and XB after fire exposure.Originality/valueThis study provides preliminary data for the development of design guidelines of bolted connections with N-bolts and XB after fire exposure.
Wavy mathematical modeling of dynamically reactive shear thinning materials under the influence of gravity and wavy structures amplitude
Authors: Rahman Atta Ur , Ahmad Latif 
Published: December 2024

PurposeResultant leading equations are formed with non-linear partial differential equations by adopting a low Reynolds theory approximation. For a better and easier understanding of the role of physical features of the main problem, the equations are reduced to non-dimensional ordinary differential equations by incorporating the locally similar and non-similar dimensionless variables. In light of practical importance, all the significant findings are approximated by solving the equations with the assistance of a modified bvp4c built-in package. The effective speed, temperature and volume fraction of the same materials are displayed to address the behaviors of different controlling influences.Design/methodology/approachThis work is inaugurated to investigate thermal cycling, thermal striping and thermal stratification, which cause thermally induced damage during the wavy confined flow domains. Such physical constraints are imposed on the wavy surface while considering the wavy dynamics of shear thinning materials. The impact of gravity is assumed on the vertical wavy surface, which is observed as the main source for the wavy flow occurrence. The surface’s amplitude plays a critical role in generating a high temperature difference. The same phenomenon is further extended with the applications of thermal radiation, mixed convection and dynamical homogeneous/heterogeneous reactions.FindingsFor instance, the higher stratification factor causes a reduction in the liquid wavy speed and temperature, and the rising chemically reactive rate factor declines the volume fraction during the typical wavy motion of the materials. Moreover, the larger amplitude and mixed convective factor reduced and uplifted the speed of the materials, respectively. The surface resistive forces are monitored with the graphical visualization of local similar skin friction and are determined larger by varying the Weissenberg and mixed convective factors. The affective liquid speed, temperature and volume fraction are plotted to address the behaviors of different controlling factors. These impacts are listed, i.e. with higher stratification factors, a reduction is noticed in the liquid velocity and temperature. On the other hand, an opposite depict is noticed for higher heat generation factors. The reduction in volume fraction is reported with variation in the reaction factor and Schmidt number.Originality/valueAfter carefully assessing the previously referenced work, it is evident that the literature has yet to incorporate thermally stratified Williamson fluid. Meanwhile, the motion of the materials is noticed due to the gravitationally affected wavy surface. Such physical phenomenon is further approximated by testing a dynamical reaction during its motion. An effective presentation of all the outcomes is portrayed via graphs and approximated numerical results.
Bridging the gap: a framework for monetizing BIM by integrating industry insights for informed decision-making
Authors: Gharaibeh Lina , Lantz Björn , Eriksson Kristina Maria 
Published: December 2024

PurposeThis study addresses the critical imperative of quantifying building information modeling (bimalliance) benefits by augmenting existing methodologies, with a focus on monetization. Engaging industry practitioners, the research develops a comprehensive framework through an exhaustive literature review and a survey in the Swedish construction industry, incorporating insights from 128 respondents.Design/methodology/approachThe framework, validated by industry experts, systematically assesses tangible BIM benefits against associated costs. It introduces a novel method in construction, addressing the lack of a unified approach. The resulting framework facilitates nuanced feasibility determinations by systematically evaluating BIM benefits against costs.FindingsDespite its acknowledged limitations, the framework effectively captures a comprehensive range of costs and benefits, providing a more accurate and detailed estimation of BIM’s impact on project outcomes.Practical implicationsWith practical implications, the framework enhances BIM understanding and application, contributing to effective project management throughout the construction supply chain lifecycle. Moreover, it aims to improve efficacy within the architecture, engineering, construction and operations industry.Originality/valueThe study empowers organizations and decision-makers with a bespoke tool for evaluating BIM feasibility, contributing to decision-making through a clarified numerical representation.
Debate: Where to next for universal school‐based mental health interventions? Addressing the mental health crisis among young people in low‐ and middle‐income countries
Authors: Coetzee Bronwyne , Loades Maria 
Published: December 2024

In their paper, Birrell et al. (Child and Adolescent Mental Health, 2025) are rightly concerned about the future of universal school‐based mental health interventions. They highlight the successes and failings of these interventions and demonstrate that there is still much to learn about their potential in preventing or mitigating the onset of common mental health conditions like anxiety, depression, trauma and substance use. But encouragingly, and thanks in part to the potential these interventions hold for addressing the mental health gap in low and middle‐income countries (LMIC), the authors advise that we as researchers need to take a step back in order to take a better step forward. They suggest that instead of abandoning ship altogether, we should critically examine the shortcomings of these interventions in their current format and work more closely with young people themselves to design and deliver interventions, which have long‐term benefits for their communities. In this paper, we want to emphasise the urgency with which these interventions, developed in this way, are needed in LMIC. We emphasise the need to co‐develop, adapt, test and evaluate school‐based interventions, and the potential they hold for reducing the burden of mental health care in resource‐constrained settings.