bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between social capital and mental health among older people living with HIV: The Sichuan Older HIV-Infected Cohort Study (SOHICS)
Authors: Han Jiayu , Jia Peng , Huang Yuling , Gao Bo , Yu Bin , Yang Shifan , Yu Jun , Xiong Jun , Liu Chang , Xie Tian , Dong Peijie , Yang Chao , Wang Zixin , Yang Shujuan 
Published: April 2020

Abstract
Background: Mental health problems are common among older people living with HIV and associated with poorer health outcomes. Social capital is an important determinant of mental health problems but under-studied in this population. This study investigated the association between social capital and mental health problems among older people living with HIV in China.
Methods: The study was based on the baseline data of a cohort study investigating mental health among older people living with HIV in Sichuan, China during November 2018 to February 2019. Participants were people living with HIV aged ≥50 years living in Sichuan province. Stratified multi-stage cluster sampling was used to recruit participants from 30 communities/towns; 529 out of 556 participants being approached completed the face-to-face interview. Social capital was measured by two validated health-related social capital scales: the Individual and Family scale and the Community and Society scale. Presence of probable depression (CES-D-10 score ≥10) and probable anxiety (GAD-7 score ≥5) were used as dependent variables. Two-level logistic regression models were applied to examine the association between social capital and probable depression/anxiety.
Results: The prevalence of probable depression and probable anxiety was 25.9% (137/529) and 36.3% (192/529) , respectively. After adjusting for significant covariates, the individual/family level of social capital was inversely associated with both probable depression (odds ratios (OR): 0.89, 95%CI: 0.84-0.93, p <0.001) and probable anxiety (OR: 0.90, 95%CI: 0.86-0.95, p <0.001). The community/society level social capital was associated with probable depression (OR: 0.91, 95%CI: 0.84-0.99, p <0.001) but not probable anxiety ( p >0.05).
Conclusions: Interventions building up social capital should be considered to improve mental health of older people living with HIV. Some useful strategies include cognitive processing therapy, improving community networking and engagement, and promoting social bonding with neighborhood.
Impact of guideline awareness in public pharmacies on counseling of patients with acute or chronic constipation in a survey of pharmacy personnel
Authors: Eberlin Marion , Landes Sabine , Biber-Feiter Doerthe , Michel Martin C. 
Published: April 2020

Abstract
Background: Constipation is often self-managed by patients and guidelines are available to aid healthcare professionals in the counseling of patients for self-management. Therefore, we have explored the knowledge and attitude of pharmacy personnel towards guidelines for the management of acute and functional chronic constipation and how they affects their recommendations.Methods: An online survey was conducted among 201 pharmacists and pharmacy technicians from an existing panel. They were presented with two typical cases, a 62-year old woman with functional chronic constipation and a 42-year old woman with travel plans. For each case, they were asked about their treatment recommendations and the underlying rationale. Thereafter, they were provided with contents from an applicable national guideline and asked again about their recommendations and the underlying rationale. In line with the exploratory nature, data were analyzed in a descriptive manner only. Results: Before exposure to guideline content, the most frequent recommendations for chronic constipation were macrogol, fiber and lactulose and for acute constipation sodium picosulfate, bisacodyl and enemas. Following guideline exposure, the most frequent recommendations for chronic constipation were macrogol, bisacodyl and sodium picosulfate and for acute constipation bisacodyl, sodium picosulfate and macrogol (all three equally recommended by the guideline for the management of acute and chronic constipation). Correspondingly, the rationale behind the recommendations shifted with guideline conformity becoming a leading reason.Conclusions: Awareness of the content of an applicable guideline on the management of constipation was poor among pharmacy personnel. Accordingly, recommendations in many cases were not in line with the guideline. Greater awareness of guideline content is desirable to enable more evidence-based recommendations in the management of constipation.
Maternal health services for pregnant adolescent girls in Uganda: Barriers and Opportunities
Authors: Namuli Vivian , Chinkonono Gorgeous Sarah , Atuhaire Catherine , Christensen Betty Nyawira , Pemunta Vitalis , Cumber Samuel Nambile 
Published: April 2020

Abstract
Background: Globally, adolescent pregnancy is one of the major areas of concern. Over 16 million girls aged between 15-19 years give birth, while over 1 million become pregnant before 15 years, most of who are in Sub-Saharan Africa. Yet, very few adolescents access maternal health services. This study explored the available maternal health services, barriers in accessing them and possible strategies for improving accessibility to these services among pregnant adolescents, specifically in Uganda.Methods: The study was carried out at Naguru teenage information and health Centre (NTIHC), Nakawa division, Kampala district using a qualitative research approach. Data was obtained using in-depth face to face interviews from 31 independent pregnant adolescents and four health care providers. These participants were selected using convenient sampling technique. Data was manually analyzed and themes were extracted and used in the interpretation of results.Results: The study found out that adolescents use only antenatal health care services while the uptake of postpartum health services was side-lined much as they were found available in the health facilities. The dominant antenatal care services among adolescents include; testing and managing of STIs, measuring pressure, tetanus vaccine, measuring weight, counselling and guidance, peer education, and providing drugs. Adolescents also encountered challenges such as long distances, financial constraints, stigmatization, negative attitude of health workers and community expressed bias when accessing these services. It further revealed that through government intervention, community and health workers, accessibility to maternal health services would be improved. Specifically, increasing remuneration for health workers; sensitizing communities about adolescent pregnancy and rights; construction of labour suites; and health workers’ competence were highly emphasized.Conclusion: Advertising and promotion of maternal health services; sensitization of community members; and government involvement will be the key parameters for enhancing maternal health care among adolescent mothers.
a Priori and Short-, Medium-, and Long-Term Social Acceptability of Innovative Robot-Assisted Gait Training by Users
Authors: bonan Isabelle veronique , Coignard Pauline , Guiet Jean luc Le , Bigot Ophelie , Denis Katell , Bidet Florient , Gautier Arnaud , Egault Jerome , Peuziat Marie Lise , Departe Jean paul , Cau Julien , Mottu Pauline , Morisset Nolwen , Pichot Nathalie 
Published: April 2020

Abstract
Background An innovative mobile and modular robot for gait rehabilitation was tested according to a psychosocial intervention framework, involving users, neuroscientists, engineers, and a social psychology laboratory. The study included a pre-design phase allowing the definition of the robot specifications. Our main objective was to study the social acceptability of the robot prototype among users and determine the relevance of the technological options chosen and the possible obstacles to the dissemination of the robot in light of the users' perceptions and experience with the robot. Methods The a priori acceptability of the robot by patients with a neurological impairment that altered their gait capacity and physical therapist (PT), both naïve to the robot, was evaluated just before its implementation in 2 rehabilitation departments and then that after 7 days (D7), and 28 days (D28), and 5 months (M5, only for the PT). The evaluation was conducted using questionnaires with Likert scale (maximum 7), according to the UTAUT (unified theory of acceptance and usage of technology) model, developed by the social psychology laboratory. Each patient participated in three 45-minute rehabilitation sessions with the robot per week for four weeks, for a total of 12 sessions, conducted by the 4 PT included. The change in the responses to the questionnaires as a function of time and the influence of the degree of gait recovery of the patients were analyzed, as well as the evolution of balance and gait parameters. Results 36 patients, mean age 58 years (SD10) and 4 PT were included. The robot was well accepted. It appeared to be useful, usable, and socially acceptable by both patients and PT and the intention to use was rated repeatedly ≥ 5. The rehabilitation activities met the functional expectations defined during the pre-design phase. In addition, a significant improvement in balance and gait was observed. Conclusion The acceptability of the robot was good for both patients and PT. Inclusion of a pre-design phase probably reduced the resistance to change often observed in healthcare organizations. The results concerning balance and gait are encouraging. They must be confirmed by a randomized controlled trial.
Provider Bias in Prescribing Opioid Analgesics: An Analysis of Emergency Department Electronic Medical Records
Authors: Aronson Brian , Keister Lisa A , Moody James 
Published: April 2020

Abstract
Background: Physicians do not prescribe opioid analgesics for pain treatment equally across groups, and such disparities may pose significant public health concerns. While research suggests that institutional constraints and cultural stereotypes influence doctors’ treatment of pain, prior quantitative evidence is mixed. The objective of this secondary analysis is therefore to clarify which institutional constraints and patient demographics truly bias provider prescribing of opioid analgesics.Methods: We used electronic medical record data from an emergency department of a large U.S hospital during years 2008-2014. We ran multi-level logistic regression models to estimate factors associated with providing an opioid prescription during a given visit while controlling for ICD-9 diagnosis and between-patient heterogeneity.Results: A total of 180,829 patient visits among 65,513 unique patients were recorded during the period of analysis. Overall, providers were significantly less likely to prescribe opioids to the same individual patient when the visit occurred during higher rates of emergency department crowding, earlier times of day, earlier times of the week, later years, and when the patient had received fewer previous opioid prescriptions. Across all patients, providers were significantly more likely to prescribe opioids to patients who were middle-aged, white, and married. We found no bias towards women and no interaction effects between race and crowding or between race and gender.Conclusions: Providers tend to undertreat pain during constrained diagnostic situations and undertreat pain for patients from high-risk and marginalized demographic groups. Harm from previous treatment mistakes are likely to accumulate through informing future treatment decisions.
Using a Hybrid Agent-Based and Equation Based Model to Test School Closure Policies
Authors: Hunter Elizabeth , Kelleher John 
Published: April 2020

Abstract
BackgroundIn order to be prepared for an infectious disease outbreak it is important to know what interventions will or will not have an impact on reducing the outbreak. While some interventions might have a greater effect in mitigating an outbreak, others might only have a minor effect but all interventions will have a cost in implementation. Estimating the effectiveness of an intervention can be done using computational modelling. In particular, comparing the results of model runs with an intervention in place to control runs where no interventions were used can help to determine what interventions will have the greatest effect on an outbreak. MethodsTo test the effects of a school closure policy on the spread of an infectious disease (in this case measles) we run simulations closing schools based on either the proximity of the town to the initial outbreak or the centrality of the town within the network of towns in the simulation. To do this we use a hybrid model that combines an agent-based model with an equation-based model. ResultsOur results show that closing down the schools in the town where an outbreak begins and the town with the highest in degree centrality provides the largest reduction in percent of runs leading to an outbreak as well as a reduction in the overall size of the outbreak compared to only closing down the town where the outbreak begins. Although closing down schools in the town with the closest proximity to the town where the outbreak begins also provides a reduction in the chance of an outbreak, we do not find the reduction to be as large as when the schools in the high in degree centrality town are closed. ConclusionsThus we believe that focusing on high in degree centrality towns during an outbreak is important in reducing the overall size of an outbreak.
A simple-to-use nomogram for the individualized prediction of multidrug-resistant tuberculosis among individuals with previous tuberculosis history
Authors: Cheng Qinglin , Zhao Gang , Wang Le , Lu Min , Li Qingchun , Wu Yifei , Huang Yinyan , Jia Qingjun , Xie Li 
Published: April 2020

Abstract
Background: So far, there are few studies that have investigated the risk of incident multidrug-resistant tuberculosis (MDR-TB) among individuals with previous tuberculosis history (PTBH), let alone developed a nomogram so as to comprehensively estimate an individualized risk of incident MDR-TB in this population. The present study was to construct a comprehensive nomogram for providing simple and precise personalized prediction of incident MDR-TB risk among individuals with PTBH.Methods: A matched case−control study (1: 2 ratios) was performed between 2005 and 2018 in Hangzhou City, China. A multivariable Cox proportional hazard regression was used to evaluate independent predictors of incident MDR-TB in individuals with PTBH. A comprehensive nomogram was developed based on the multivariable Cox model.Results: Overall, 1, 836 participants were included in this study. We developed a simple-to-use nomogram for predicting the individualized risk of incident MDR-TB by using the parameters of age < 60 years, a history of direct contact, passive mode of TB case finding, human immunodeficiency virus infection, re-treated TB history, unsuccessful treatment, 3HRZES/6HRE, duration of pulmonary cavities, and duration of positive sputum culture in individuals with PTBH. The concordance index of this nomogram was 0.833 [95% confidence interval (CI): 0.807-0.859] and 0.871 (95% CI 0.773-0.969) for the training and validation sets, respectively, which indicated adequate discriminatory power. The calibration curves for the risk of incident MDR-TB showed an optimal agreement between nomogram prediction and actual observation in the training and validation sets, respectively. The high sensitivity and specificity of nomogram was indicated by using a receiver operating characteristic curve analysis.Conclusions: We developed and validated a novel nomogram for predicting and preventing the risk of incident MDR-TB in individuals with PTBH. Through this clinic tool, TB control executives could more precisely monitor, estimate and intervene the risk of incident MDR-TB among individual PTB patients.
Knowledge, Attitude and Practice Associated with COVID-19 among University Students: a Cross-Sectional Survey in China
Authors: Peng Yaling , Pei Chenchen , Zheng Yan , Wang Juan , Zhang Kui , Zheng Zhaohui , Zhu Ping 
Published: April 2020

Abstract
BackgroundThe current COVID-19 pandemic is effectively constrained by intensified public health measures in China, among which ubiquitous education plays a vital part.ObjectiveThis survey aims to understand the status quo acquisition of the ongoing public health education campaign among university students. MethodsWe designed this cross-sectional survey to investigated the knowledge, attitude and practice (KAP) associated with COVID-19 among university students during their household isolation at the peak of this pandemic. 872 university undergraduates were recruited from 10 universities in Shaanxi Province, China, in a stratified cluster sampling method. A self-administered and close-ended questionnaire was answered by subjects online voluntarily and anonymously to collect their answers regarding their KAP associated with COVID-19.ResultsResults showed that appropriate knowledge was acquired by 82.34% subjects, but the level was significantly higher in students from public universities and medical programs than in their counterparts (P＜0.05). 73.81% subjects reported positive attitude, with level significantly higher in females (P＜0.01). Proactive practice was found in 87.94% subjects. Taken together, the score of KAP was 4.12±0.749, 8.54±1.201, and 8.91±1.431 respectively, suggesting a positive correlation between attitude and practice (r=0.319, P＜0.01). Total KAP score was 21.57±2.291, apparently correlated with gender (r=0.096, P=0.005) and major (r=-0.081, P=0.017).Conclusions﻿Most university students acquired necessary knowledge, positive attitude and proactive practice towards COVID-19, but their KAP score significantly varied by gender, major and school type.
Why do you wear a face mask? Taiwanese public epidemic awareness of COVID-19 from social media behavior
Authors: Chin Chih-Yu , Liu Chang-Pan , Wang Cheng-Lung 
Published: April 2020

Abstract
BackgroundFacing the COVID-19 epidemic, Taiwan has demonstrated resilience at the initial stage of epidemic prevention and effectively slowed down its spread. This study aims to capture public epidemic awareness toward the COVID-19 through collecting social media- and Internet-based data and elaborate on how the public epidemic awareness rose and played a role in the epidemic prevention in Taiwan during the initial course of COVID-19 spread.MethodsUsing the Google search query volume of COVID-19 and face mask as indicators of public epidemic awareness, we collected the volume of news reports and the mentions on social media about COVID-19 and face masks between December 31, 2019, and February 29, 2020, through big data analysis and sorted the daily total confirmed cases of COVID-19 worldwide and in Taiwan as well as critical mask-related measures implemented by the Taiwanese government to plot the trends in this information and conduct correlation analysis. Additionally, the content analysis was adopted to analyze the transmission of different types of fear information of COVID-19 between December 31, 2019, and March 29, 2020, and their effects on the public.ResultsThe Google search query volume of COVID-19 and face mask was significantly correlated with the number of confirmed cases in Taiwan, the number of news reports on COVID-19 (correlation coefficient: .74–.90). Since the first confirmed cases of COVID-19, public epidemic awareness has increased rapidly, prompting the government to formulate relevant emergency measures. Additionally, the findings from content analysis suggested that the fear of the loss of control best explains why panic behavior occurs in public.ConclusionsConfronting the highly infectious COVID-19, public epidemic awareness is vital. While fear is an inevitable product when an emerging infectious disease occurs, the government can convert resistance into assistance by understanding why fear arises and which fear factors cause excessive panic in public. Moreover, online social media promptly reflect public epidemic awareness, which can be used as a reference for epidemic prevention; this urges the government to deal with the crisis in the form of public opinion.
Influences of dietary Eucommia ulmoides extract on growth, flesh quality, antioxidant capacity and collagen-related genes expression in grass carp (Ctenopharyngodon idellus)
Authors: Yang Hang , Tan Sumei , Li Xiaoqin , Xu Zhen , Cheng Zhuo , Leng Xiang-jun 
Published: April 2020

Abstract
Background: The study investigated the effects of dietary Eucommia ulmoides extracts on growth, flesh quality and collagen-related genes expression of grass carp (Ctenopharyngodon idella). Eucommia ulmoides bark extract (EBE) and Eucommia ulmoides leaf extract (ELE) were individually supplemented into basal diet (control) at an inclusion of 4 g/kg, and then the three diets were fed to grass carp (59.7 ± 0.3g) for 60 days. Results: The results indicated that dietary ELE significantly increased weight gain (+4.22%), and decreased feed conversion ratio (-0.07) (P<0.05), while EBE did not significantly affect the growth performance of grass carp. Compared to the control, dietary ELE increased apparent digestibility coefficient of dry matter, crude protein and intestinal digestive enzyme activity (P<0.05), and the contents of calcium, total collagen, heat-insoluble collagen and free amino acids level (including delicious amino acids) in flesh were also increased (P<0.05). In both extracts groups, the flesh centrifugal loss, steaming loss, drip loss24h, protein carbonyl and malondialdehyde were significantly lower, and superoxide dismutase and glutathione peroxidase activities were higher than the control (P<0.05). No significant differences in the amount of saturated, monounsaturated and polyunsaturated fatty acids in flesh were found among the three groups, but DPA, DHA, n-3 polyunsaturated fatty acids and n-3/n-6 ratio in flesh were increased by dietary EBE and ELE (P<0.05). In collagen-related genes expression, the ELE supplementation significantly promoted the expression of collagen type Ⅰ (COL1A1, COL1A2), proline hydroxylase, lysine oxidasein in muscle, while the expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 was decreased (P<0.05). Conclusion: In conclusion, dietary ELE improved the growth, muscle antioxidant capacity and flesh quality of grass carp.