bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nasopharyngeal mucoepidermoid carcinoma: a rare tumor in nasopharynx
Authors: Seong Kin Foong , Jeing Yong Doh , Azman Mawaddah Binti 
Published: October 2019

<p class="abstract">Mucoepidermoid carcinoma (MEC) is a malignant epithelial salivary gland neoplasm which consists of a mixture of mucin-producing columnar cells, epidermoid (squamous) cells and polygonal intermediate cells. Salivary gland-type carcinomas are extremely rare to be found in the nasopharynx. A 46-year-old lady presented with bilateral progressive nasal blockage and occasional epistaxis for 3 years. However, there was no neck swelling. Nasoendoscopy revealed a huge nasopharyngeal mass. Tissue biopsy in clinic setting reported of inverted papilloma. Computed tomography shows large irregular heterogenously enhancing mass in nasopharynx. Posterior septectomy was done for the access and endoscopic excision of nasopharyngeal tumor was performed. Histopathological examination confirmed the tumor is mucoepidermoid carcinoma. Postoperative adjuvant concurrent chemoradiotherapy with total of 66 Gy was commenced in view of concern of possible residual microscopic disease. Nasopharynx is an uncommon site for MEC. MEC patients seldom has enlarged neck node at presentation.Nasopharyngeal salivary gland-type carcinomas does not commonly cause cranial nerve palsy compared to nasopharyngeal carcinoma (NPC). In cases with huge nasopharyngeal mass without neck nodes and cranial nerves involvement, MEC can be a differential diagnosis. Surgical removal of gross disease and concurrent chemoradiotherapy as an adjuvant treatment for likely residual microscopic disease is the standard treatment for nasopharyngeal mucoepidermoid carcinoma.</p>
Poética de la imagen - imagen poética
Authors: Jaramillo Hoyos Alejandro 
Published: October 2019

El artículo expone y reflexiona sobre la experiencia en un curso de maestría sobre usos sociales y políticos de la imagen en 2012. El trabajo con un grupo de estudiantes, capacitados en diferentes disciplinas, comenzó con la identificación de la historia personal de esas huellas digitales o hitos que se han quedado con imágenes que permanecen como una parte importante en el desarrollo personal.
Desde este marco, la imagen se extendió a la indagación sobre el lugar que las imágenes tienen en otros círculos o esferas de la vida como las relaciones cercanas y sociales. Como resultado, cada participante creó un montaje de imágenes que constituye una nueva pista y se da cuenta de la realidad transformada por la autoobservación y la reflexión compartida.
Adding Compost to Oil Palm Planting Holes can Increase the Diversity of Soil Fungi without Significantly Affecting the Gas Emissions on Wetlands
Authors: Nur Hasrul Satria , Hadi Abdul , Yuliani Rindang 
Published: October 2019

<p>The use of chemical fertilizers have been negative impact on environment, especially in increased the gas emissions and reduced the diversity of microbes, such as bacteria, actinomycetes, and soil fungi. As the one of the alternatively is used the combined compost. For instance, grass compost with the added of inorganic fertilizer (chemical), oil palm empty fruit bunches compost with the added of inorganic fertilizer, and the inorganic fertilizer without compost. The measuring of gas emissions was carried out on CH<sub>4</sub>, CO<sub>2</sub> and N<sub>2</sub>O at several of the oil palm planting holes. Every sample gases were collected by the chambers installed with syringe. .Thus, the gas emissions were analyzed by chromatography gas type GHG 450 Shimadzu. Besides that, the diversity of soil fungi were also determined by the characterization and identification. The result of this research showed of reducting on CH<sub>4 </sub> that was appplied by the combined of oil palm empty fruit bunch compost with inorganic fertilizers i.e., 0.019 until-0.316 g CH<sub>4</sub>.m<sup>-2</sup>.h<sup>-1</sup>. The same patterns were also demonstrated by CO<sub>2</sub> from the treament of oil palm empty fruit bunch with inorganic fertilizers, viz 755.246 untill-2.331 g CO<sub>2</sub>.m<sup>-2</sup>.h<sup>-1</sup>. Relating to N<sub>2</sub>O, it has undergone reduced by grass compost with inorganic fertilizers, viz-27.726 until-25.622 mg N<sub>2</sub>O.m<sup>-2</sup>.h<sup>-1</sup> . Meanwhile, the genera of soil fungi that were found on the sites after applying combining compost, viz <em>Aspergillus, Bipolaris, Gonatobotrys, Gonatorrhodiella, Oidiodendron, Penicillium, Rhynchosporium, Rhizopus, Trichoderma,</em> and <em>Trichocladium</em>. Therefore, the use of compost with combining chemical fertilizers are potentially to apply into the oil palm field on wetlands.</p><p> </p>
LACUSTRINE SYSTEMS IN THE EARLY MIOCENE OF NORTHERN SOUTH AMERICA—EVIDENCE FROM THE UPPER MAGDALENA VALLEY, COLOMBIA
Authors: DE LA PARRA FELIPE , PINZON DIEGO , RODRIGUEZ GUILLERMO , BEDOYA OMAR , BENSON ROGER 
Published: October 2019

ABSTRACTExtensive areas covered by semi-permanent water bodies were common during the Miocene in the Neotropics. These floods are noteworthy because of their possible role in promoting the high biological diversity observed today in the Amazonia. In particular, a relatively good understanding of the floods has been achieved for the Llanos basin of Colombia and western Amazonia. In these two basins the evidence suggests episodes of marine incursions and development of lacustrine systems at different times during the Miocene. Other intra-montane basins in Colombia, like the Middle and Upper Magdalena basins, also show clear evidence that water bodies covered them during that time. However, the chronostratigraphy and paleoecology of these deposits are still unclear. In this study, we use the palynological record of the Middle and Upper Magdalena valleys to establish the age of the deposits of the Barzalosa Formation, a unit that preserves a detailed record of a lacustrine system deposited during the late early Miocene in the Upper Magdalena Valley. The results indicate that the Barzalosa Formation is correlative with the lacustrine deposits of the La Cira fossiliferous horizon in the Middle Magdalena Valley. This indicates that extensive lacustrine systems covered the intramontane basins of the northern Andes during the early Miocene. Paleoecologically, the Barzalosa Formation is the result of the evolution of a lacustrine system in three phases, which show marked differences in the proportion of algae, palynological composition and sedimentary depositional sequence. Climate and tectonic processes were the most probable mechanisms controlling the evolution of the Barzalosa system.
Waterflood Performance Analyses for the Bhagyam Viscous Oil Reservoir
Authors: Shankar Vivek , Beliveau Dennis , Jain Shakti , Jha Bhawesh Chandra , Tiwari Arjun , Singh Chandan Kumar , Rautela Chandra Mohan S. , Stanley Matthew , Chapman Thomas 
Published: October 2019

Summary
The Bhagyam field contains medium-gravity viscous crude oil. Notably, its waterflood performance has been substantially worse than projected in its initial field development plan (FDP) and poorer than in nearby analog fields and other viscous oil waterfloods from around the world.
Early simulation models could not replicate Bhagyam waterflood performance without numerous major modifications. Poor performance was initially attributed to unforeseen severe heterogeneity. As data accumulated, conceptual simulations showed that an extreme level of heterogeneity was required to match observed performance, suggesting permeability heterogeneity alone could not explain results. Log data from later infill wells also showed that injected water was not confined to high-permeability streaks but was areally and vertically widespread.
Two major changes drove significant improvements in waterflood simulation history matches. First, a new porosity/permeability model calibrated to pressure falloff (PFO) tests in the aquifer resulted in a higher degree of heterogeneity, which accelerated water production in updated simulation models. Second, a new oil/water relative permeability model that accounted for the hypothesized presence of a small, solid wax saturation reduced initial oil relative permeability and predicted oil rates, and further accelerated water production. Resulting simulation models showed excellent history matches and have continued to match performance during the past 2 years with only minor additional modifications.
Genome wide quantification of A-to-I RNA editing activity
Authors: Roth Shalom Hillel , Levanon Erez Y. , Eisenberg Eli 
Published: October 2019

Abstract
Adenosine to inosine (A-to-I) RNA editing by the ADAR enzymes is a common RNA modification, preventing false activation of the innate immune system by endogenous dsRNAs. Methods for quantification of ADAR activity are sought after, due to an increasing interest in the role of ADARs in cancer and auto-immune disorders, as well as attempts to harness the ADAR enzymes for RNA engineering. Here we present the Alu Editing Index (AEI), a robust and simple-to-use computational tool devised for this purpose that produces a single number representing the global editing level from BAM files. The AEI tool is available at https://github.com/a2iEditing/RNAEditingIndexer
Knowledge and Associated Factors About Cataract Among Adults in Northeast Ethiopia
Authors: Mohammed Seid , Alemu Haile Woretaw , Admassu Fisseha 
Published: October 2019

Abstract
Background: Cataract is the leading cause of blindness globally and accounts for half of the total blindness in Ethiopia. Despite it is treatable, the lack of knowledge about cataract and its treatment is still a major barrier in the developing countries. Knowledge about the disease and its treatment play a key role for the people with cataract to get timely eye care. Objective: To assess knowledge and associated factors about cataract among adults in Kombolcha, Northeast Ethiopia Methods: Community-based cross-sectional study was implemented. Stratified multistage sampling technique was used to select a total of 847 study participants aged 18 years or older. A face to face interview was applied using a pretested structured questionnaire in Amharic language. The collected data was entered into Epidemiological information version 7 and exported to statistical package for social sciences version 20 for analysis. Descriptive statistics and binary logistic regression with odds ratio were used. Variables with a p-value of less than 0.05 in multivariable logistic regression were considered as statistically significant predictors for knowledge about cataract. Results: A total of 771 participants completed the study with a response rate of 91%. Of the total, 86.0% were from urban kebeles and 50.8% were female. The median age of the participants was 30 years. About 75.6% (583) individuals were familiar with the term cataract. Overall 537 )69.6%) [95% CI: 66.3-72.9] had good knowledge of cataract. Higher educational status [AOR: 6.041; 95% CI: 3.106-11.746], being married [AOR: 1.787; 95% CI: 1.174-2.721], having history of a previous eye examination [AOR: 1.619; 95% CI: 1.053-2.488] and positive history of cataract [AOR: 10.443; 95% CI: 2.078-52.493] were significantly associated with good knowledge about cataract. Conclusions: Overall about two-third of participants had good knowledge about cataract. Higher educational status, being married, having a previous eye examination and a positive history of cataract had a significantly positive association with good knowledge about cataract. As cataract is a leading blinding disease, maximizing the existing knowledge by giving special attention to those not having formal education is essential.
Comparison of Decompression Alone and Decompression Combined with Fusion for Treating Lumbar Degenerative Spondylolisthesis
Authors: xin wenqiang , Xin Qi-qiang , yang xinyu 
Published: October 2019

Abstract
Background To assess the necessity or not of the addition of fusion to decompression for lumber degenerative spondylolisthesis patients.Method Potential publications were selected from PubMed, Web of Science and Cochrane Library. Gray relevant studies were manually searched. We set the searching time spanning from the creating date of electronic engines to August 2019. STATA version 11.0 was exerted to process the pooled data.Results Six RCTs were selected in our analysis. A total of 650 participants were divided into 275 in the decompression group and 375 in the fusion group. Our meta-analysis showed negative results generally. No statistic differences were found in VAS score for low back pain (WMD, -0.045; 95%CI, -1.259 to 1.169; P=0.942) and leg pain (WMD, 0.075; 95% CI, -1.201 to 1.35; P=0.908), ODI score (WMD, 1.489; 95% CI, -7.232 to 10.211; P=0.738), EQ-5D score (WMD, 0.03; 95% CI, -0.05 to 0.12; P=0.43), Odom’s classification (OR, 0.353; 95%CI 0.113, 1.099; P=0.072), postoperative complications (OR, 0.437; 95% CI, 0.065 to 2.949; P=0.395), secondary operation (OR, 2.541; 95% CI 0.897, 7.198; P=0.079) and postoperative degenerative spondylolisthesis (OR=8.59,P=0.27). Subgroup analysis in VAS score on low back pain (OR=0.77, 95% CI, 0.36 to 1.65; P=0.50) was demonstrated as no meaning as well.Conclusion The overall efficacy of the combination of decompression and fusion is not found to be superior to decompression alone. At the same time, more evidence-based performance is needed to supplement this opinion.
Work-related musculoskeletal disorders among nurses in the intensive care units and respiratory care centres: A pilot cross-sectional descriptive study
Authors: Kuo Fang-Yu , Chen Kuan-Lin , Chen Po-Hung 
Published: October 2019

Abstract
Background To evaluate the prevalence and associated risk factors of work-related musculoskeletal disorders (WMSDs) in nurses working in hospital intensive care units (ICUs) and respiratory care centres (RCCs) and to provide additional information and recommendations.Methods This pilot cross-sectional descriptive study was conducted in a tertiary medical centre, involving hospital staff working in the ICUs between June 2015 and March 2016. We assessed their Neck Disability Index (NDI) and Oswestry Disability Index (ODI) score grouping by age, care unit types and job tenure.Results In all, 139 staff members completed the questionnaire. The mean age was 30.2 ± 6.0 years, and the mean body mass index was 22.5 ± 3.9 kg/m 2 . The mean job tenure in the ICU was 6.5 ± 5.2 years, and the mean total job tenure was 8.1 ± 6.3 years. The mean working day per week was 5.1 ± 0.5. The mean working hours using computer per day was 4.8 ± 2.8. The mean NDI score was 7.6 ± 4.8, and the mean ODI score was 3.4 ± 5.1.Conclusion Neck and low-back disabilities are prevalent among staff members in the ICUs and RCCs. Staff members may benefit by undergoing rehabilitation programmes, such as therapeutic exercises and postural training. More attention should be paid to the neck and back disability status of staff members in the ICUs and RCCs to improve the working environment and ergonomics. Further research is warranted to evaluate whether WMSDs improve among ICU and RCC staff after performing exercise and receiving physical therapy.
Meaningful Information in the Age of Big Data: A Scoping Review on Social Determinants of Health Data Collection for Electronic Health Records
Authors: Berg Kelsey , Doktorchik Chelsea , Quan Hude , Saini Vineet 
Published: October 2019

Abstract
Background: Electronic Health Records (EHRs) are key tools for integrating patient data into health information systems (IS). Advances in automated data collection methodology, particularly the collection of social determinants of health (SDOH), provide opportunities to advance health promotion and illness prevention through advanced analytics (i.e. “Big Data” techniques). We ask how current data collection processes in EHRs permit SDOH data to flow throughout health systems. Methods: Using a scoping review framework, we searched through medical literature to identify current practices in SDOH data collection within EHR systems. We extracted relevant information on data collection methodology, specifically focusing on uses of automated technology. We discuss our findings in the context of research methodology and potential for health equity. Results: Practitioners collect a variety of SDOH data at point of care through EHR, predominantly via embedded screening tools and clinical notes, and primarily capturing data on financial security, housing status, and social support. Health systems are increasingly using digital technology in data collection, including natural language processing algorithms. However overall use of automated technology is limited to date. End uses of data pertain to improving system efficiency, patient care-coordination, and addressing health disparities. Discussion & Conclusion: EHRs can realistically promote collection and meaningful use of SDOH data, although EHRs have not extensively been used to collect and manage this type of information. Future applied research on systems-level application of SDOH data is necessary, and should incorporate a range of stakeholders and interdisciplinary teams of researchers and practitioners in fields of health, computing, and social sciences.
SKY59, A Novel Recycling Antibody for Complement-mediated Diseases
Authors: Fukuzawa Taku , Nezu Junichi 
Published: October 2019

Background:The complement system usually helps protect against microbial infection, but it could also be involved in the onset of various diseases. Inhibition of complement component 5 (C5) with eculizumab has resulted in a significant reduction of hemolysis, reduction of thromboembolic events, and increased survival in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH). However, eculizumab requires frequent intravenous infusions due to the abundance of C5 in plasma and some patients may still experience breakthrough hemolysis. This review introduces the recent body of knowledge on recycling technology and discusses the likely therapeutic benefits of SKY59, a novel recycling antibody, for PNH and complement-mediated disorders.Methods:By using recycling technology, we created a novel anti-C5 antibody, SKY59, capable of binding to C5 pH-dependently.Results:In cynomolgus monkeys, SKY59 robustly inhibited C5 and complement activity for significantly longer than a conventional antibody. SKY59 also showed an inhibitory effect on C5 variant p.Arg885His, whereas eculizumab does not suppress complement activity in patients with this type of mutation.Conclusion:SKY59 is a promising anti-C5 biologic agent that has significant advantages over current therapies such as long duration of action and efficacy against C5 variants.
Utility of CD4 Cell Count and Viral Load Assay in Hospitalized Patients with Known HIV Infection: High Value Care Exercise
Authors: Lal Amos , Abraham George M. 
Published: October 2019

Purpose:
Healthcare spending as a percentage of Gross domestic product (GDP) is at
all-time high and continues to rise in the United States. The Centers for Medicare and Medicaid
Services estimate that 33% of resources spent on healthcare goes to waste. As part of a ‘high value
care’ exercise, we studied if estimating CD4 cell counts and HIV viral load in hospitalized patients
with a known diagnosis of HIV led to any meaningful change in HAART regimen and discharge
diagnosis.

Methods:
Retrospective chart review for all patients admitted with a known diagnosis of HIV
from January 1, through December 31, 2017.

Results:
A total of 83 patient encounters were reviewed during the period. The mean age was 54.1
± 16.4 years, 64.1 % of patients were males. 75 patients (90.3%) were already on highly active
antiretroviral therapy (HAART). The median hospital length of stay (LOS) was 3 days (IQR 2.0 -
5.0). The mean turnaround time for CD4 counts and HIV viral load assay was 2.9 days (95% CI
2.1 – 3.7) and 3.9 days (95% CI, 3.2 – 4.6), respectively. A CD4 count estimation led to no
change in HAART regimen. HIV viral load assay testing had no impact on a change in treatment
or a change in diagnosis.

Conclusions:
In our study, testing CD4 counts and HIV viral load for inpatients did not confer
any benefit in altering the diagnosis or HAART regimen. We believe that our study identifies a
systems level opportunity to add to the concept of ‘Choosing Wisely.’
Weighted K-nearest Neighbor Fast Localization Algorithm Based on RSSI for Wireless Sensor Systems
Authors: Bai Lu , Du Chenglie , Chen Jinchao 
Published: October 2019

Background:
Wireless positioning is one of the most important technologies for realtime
applications in wireless sensor systems. This paper mainly studies the indoor wireless positioning
algorithm of robots.

Methods:
The application of the K-nearest neighbor algorithm in Wi-Fi positioning is studied by
analyzing the Wi-Fi fingerprint location algorithm based on Received Signal Strength Indication
(RSSI) and K-Nearest Neighbor (KNN) algorithm in Wi-Fi positioning. The KNN algorithm is
computationally intensive and time-consuming.

Results:
In order to improve the positioning efficiency, improve the positioning accuracy and reduce
the computation time, a fast weighted K-neighbor correlation algorithm based on RSSI is proposed
based on the K-Means algorithm. Thereby achieving the purpose of reducing the calculation
time, quickly estimating the position distance, and improving the positioning accuracy.

Conclusion:
Simulation analysis shows that the algorithm can effectively shorten the positioning
time and improve the positioning efficiency in robot Wi-Fi positioning.
Percepción de la relación comercial entre el productor de palma de aceite y su cliente principal: departamento del Meta – Javier Vargas – Paula Arias – José Santos – Laura Parra – Ingrit Fandiño – Darline Gallo – Charles Arosa
Authors: Vargas Urrego Javier Orlando , Arias Melo Paula Andrea , Santos Barbosa José Daniel , Parra Riaño Laura Constanza , Fandiño Jimenez Ingrit Natalia , Gallo Ramirez Darline Eleane , Arosa Carrera Charles Robin 
Published: October 2019

La presente ponencia tiene como objetivo caracterizar las relaciones comerciales entre los productores de palma de aceite y su cliente principal, donde se describe la equidad percibida que tienen los agricultores con respecto a las condiciones que median la transacción. El análisis se realiza por zonas de producción (Centro, Pie de Monte y Altillanura) en el departamento del Meta, teniendo en cuenta las variables como tamaño, tiempo de cultivo y formalización de la empresa, que pueden incidir en la forma en que se relaciona éste primer eslabón de la cadena de palma de aceite con su cliente, el cual en su mayoría son extractoras. Cada Zona presenta singularidades, las cuales son importante comprender, mucha de ellas dependen por lo general de la clase de productor que se establezca en la zona, pues en algunos territorios hay gran informalidad en el productor, el cual posee pequeños y medianos cultivos, por otro lado están las empresas formales que cuentan con grandes extensiones de siembra, con intereses diferentes a nivel comercial y una mayor integración hacia adelante.