bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation Of Dentoalveolar, Skeletal and Soft-Tissue Changes With FFA Including The Multibracket System: A Meta-analysis
Authors: Premsagar Shruti , Kumar Mukesh , Sharma Hemant , Goyal Manish , Kushwah Ashish , Sharma Sonika 
Published: July 2020

Objective: To assess skeletal, dentoalveolar, and soft-tissue effects of fixed functional appliances (FFAs), alone or in combination with multibracket appliances (comprehensive treatment), on Class II malocclusion in postpubertal patients. Data Sources: Literature survey was conducted using the Medline, SCOPUS, Latin American and Caribbean Health Sciences, and Scientific Electronic Library Online databases and the Cochrane Library, and through a manual search. No restrictions were set regarding the type of fixed appliance, treatment length, or to the cephalometric analysis used. Data extraction was mostly predefined at the protocol stage by 2 authors. Study Selection: Only double-blind randomized controlled trials (RCTs) of Class II skeletal cases treated by any FFA that had assessed specific skeletal, dental, or soft-tissue parameters were included. Data Synthesis: A total of 8 articles qualified for the final analysis. The studies were composed of late-adolescent or adult patients who were at the end of their postpubertal growth period. This meta-analysis included data from 271 subjects (142 Class II patients and 129 untreated individuals) and 8 RCTs, which assessed linear as well as angular cephalometric changes induced by Class II treatment with FFAs. Conclusions: Based on the data available on postpubertal patients, it was concluded that the fixed functional treatment is effective in Class II malocclusion and shows changes in skeletal, dental, as well as soft tissue.
Impact of COVID-19 Lockdown on Patients Undergoing Orthodontic Treatment: A Questionnaire Study
Authors: Shenoi Susmita Bala , Deshpande Sumedh , Jatti Roopa 
Published: July 2020

With COVID-19 declared as a worldwide pandemic, a nationwide lockdown was implemented overnight in India on March 24, 2020. With no prior warning or anticipation, patient appointments were temporarily ceased as institutions and clinics were indefinitely closed. To our knowledge, no study addresses the orthodontic patient perspective in such testing times, where they are entirely restricted to the confines of their homes. Aim: To assess the impact of the COVID-19-related lockdown on the treatment and psychology of patients undergoing orthodontic treatment. Material and methods: A self-designed online exploratory questionnaire of 15 questions was distributed to 500 potential responders selected from obtained lists through messages and emails. It was mandatory to answer all questions and the survey was anonymized and did not contain any identifying information. Online consent was taken before participation in the study. The obtained data were evaluated using descriptive and inferential statistics. Results: The response rate was 81.6%. The study revealed that the majority of patients were affected by the lack of access to orthodontic visits. The reasons for the same were attributed to fear of increased treatment duration, inconveniences caused by poking wires, broken brackets, etc., and lack of communication between the orthodontists and patients, among the various other reasons. The importance of orthodontic appointments was also understood by patients. Conclusion: The study threw light on the essential need for understanding the psychology of patients undergoing orthodontic treatment. In any situation where patients do not have access to seek help, all the factors discussed in the study should be considered and it is of utmost importance that orthodontic professionals see to it that their patients are being looked after mentally, if not physically, in whatever way possible.
Is the Relationship Between Government Spending and Private Consumption in Egypt Symmetric?
Authors: Almosabbeh Imadeddin Ahmed 
Published: July 2020

The aim of this study, using Egyptian data from 1970 to 2016, is to explore the relationship between government spending and private consumption spending and to understand whether the relationship between the two is symmetric. The study uses the autoregressive distributed lag (ARDL) approach to explore a cointegration relationship between the two variables, and the nonlinear autoregressive distributed lag (NARDL) approach to test the hypothesis of a symmetric relationship between the two variables. By applying the ARDL approach, the study concludes that the effect of government spending on consumption spending is not significant in the long term. By applying the NARDL approach, the study concludes that: the hypothesis of the presence of a symmetric relationship is not accepted, there is a crowding-out relationship from the positive shocks of government spending and the substitutability coefficient between the two types of spending is 0.8699. JEL Classification: E12, E21, F62, H50
Physical Health in Adults Born With Cleft Lip and/or Palate: A Whole of Life Survey in the United Kingdom
Authors: Ardouin Kenny , Davis Sinéad , Stock Nicola Marie 
Published: July 2020

Objectives: Previous research in the field of cleft lip and/or palate (CL/P) has indicated a high prevalence of common health concerns, functional difficulties, and additional conditions known to affect long-term physical health, cognitive development, and psychological well-being. The aim of the present study was to examine the self-reported physical health of a national sample of adults born with CL/P. Design: Drawing upon previous literature, an online, mixed-methods survey was designed by the Cleft Lip and Palate Association in collaboration with the Centre for Appearance Research at the University of the West of England. A total of 207 eligible responses were received between July and October 2018. Qualitative data were analyzed using inductive content analysis, while quantitative data were analyzed using descriptive statistics. Results: A considerable proportion of participants reported one or more comorbid conditions, including common health concerns, difficulties related to language and/or learning, unresolved speech and/or hearing issues, problems with vision, breathing difficulties, and concerns related to eating and drinking. Many participants were unaware of their entitlement to specialist treatment, and some had experienced difficulties accessing specialist services through their general practitioner (GP). Conclusions: Individuals with CL/P may be at risk of physical health issues persisting into adulthood. The monitoring of physical symptoms from an early age is recommended, as is a routine physical assessment for adults returning to the CL/P service later in life. Education for both GPs and adults is warranted. Future studies could investigate the wider prevalence of comorbid conditions in CL/P, in order to better understand the longer-term health burden.
The effectiveness of ocriplasmin versus surgery for the treatment of macular holes: A systematic review and meta-analysis
Authors: Yu Brian Edward , Sheidow Tom , Sambhi Raman-Deep Singh , Hooper Phil , Malvankar-Mehta Monali S. 
Published: July 2020

Objective: To conduct a systematic review looking at the effects of ocriplasmin compared to pars plana vitrectomy on macular holes to assess the effectiveness of the treatment options. Methods: Literature was searched through MEDLINE, EMBASE, CINAHL, Clinical Trials.gov, and ProQuest Dissertations and Theses until June 12, 2018. Conferences held through Association for Research in Vision and Ophthalmology, Canadian Society of Ophthalmology, and American Academy of Ophthalmology were searched until June 18, 2018. A total of 208 records were screened leaving 26. One author independently reviewed them for quality and extracted data. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines were followed. The adverse events, MH closure rate, change in MH size, and the extent to which the patients’ visual acuity is restored by each treatment option; ocriplasmin and vitrectomy. Results: Twenty-six articles were included for qualitative and quantitative analysis. Meta-analysis results showed a 34% closure of macular holes after ocriplasmin treatment compared to 92% after vitrectomy. A significant improvement in visual acuity was seen after vitrectomy (SMD = −1.42; CI: [−1.98, −0.86]) as well as the ocriplasmin treatment (SMD = −0.73; CI: [−0.98, −0.48]). Conclusions: Results suggested 92% macular hole closure after vitrectomy compared to 34% after ocriplasmin. A significant improvement in visual acuity of patients was seen after both treatments. More good quality randomized controlled trials are required to make strong conclusions.
Bilinguals’ and monolinguals’ performance on a non-verbal cognitive control task: How bilingual language experience contributes to cognitive performance by reducing mixing and switching costs
Authors: Khodos Iryna , Moskovsky Christo , Paolini Stefania 
Published: July 2020

Aims and objectives/purpose/research questions: The study investigated whether language experience predicts cognitive performance in bilingual and monolingual adults. As indicators of language experience, we focused on language context, typological proximity/distance between two languages and onset age of active bilingualism. As indicators of cognitive performance, we measured mixing costs and switching costs to gauge proactive and reactive control processes during a computerized non-verbal cognitive control task. Design/methodology/approach: Demographic and language data were collected with the Language and Social Background Questionnaire. Mixing and switching costs were subsequently obtained using a cued non-verbal switching task. Data and analysis: The background and switching-task data obtained from 60 bilinguals from non-English-speaking backgrounds and 24 English monolinguals residing in Australia were analysed using linear fixed-effects regression analyses. Findings/conclusions: The results showed that the use of two languages in a dual-language context was associated with reduced switching costs relative to monolingual and bilingual separated-language contexts and with reduced mixing costs only relative to a bilingual separated-language context. Among the bilinguals, lower mixing costs were also associated with an earlier onset age of active bilingualism and smaller typological distance between two languages. Originality: This study’s design included bilinguals as a target group and monolinguals as a control group, thus enabling the identification of possible mixing and/or switching cost advantages in bilinguals. By targeting young/middle-aged adults and considering a set of potentially relevant language experiences, this work was, therefore, well placed to provide clarity on findings for an age group that previously returned mixed and inconclusive results regarding a bilingual advantage. Significance/implications: Our findings reinforce the idea that particular dimensions of bilingual experience rather than bilingualism per se are linked to enhanced cognitive performance.
Resuscitation during the pandemic: Optional obligation? or supererogation?
Authors: Perkins Jonathan , Hamilton Mark , Canniff Charlotte , Gannon Craig , Illsley Marianne , Murray Paul , Scribbins Kate , Stockwell Martin , Wilson Justin , Gallagher Ann 
Published: July 2020

This paper is a response to a recent BMJ Blog: ‘The duty to treat: where do the limits lie?’ Members of the Surrey Heartlands Integrated Care Service Clinical Ethics Group (CEG) reflected on arguments in the Blog in relation to resuscitation during the COVID-19 pandemic. Clinicians have had to contend with ever-changing and conflicting guidance from the Resuscitation Council UK and Public Health England regarding personal protective equipment (PPE) requirements in resuscitation situations. St John Ambulance had different guidance for first responders. The situation regarding resuscitation led the CEG to consider ethical aspects of health care professionals’ responses to the need for resuscitation during COVID-19. Members agreed that professionals should, ideally, have the level of PPE required for an aerosol generating procedure. However, there was no consensus regarding professionals’ duty to care when this is not available. On the one hand, it was agreed that the casualty/patient’s interests regarding resuscitation should be prioritised due to professionals’ contract with the public and professional privilege. On the other hand, risk thresholds were considered relevant to individual decision-making and professionals’ duty to care. All agreed that decision-making should not be influenced by rewards or reprimands. It was agreed also that decisions to resuscitate should not be considered as moral heroism or supererogatory - regardless of PPE availability - but rather as ‘minimally decent’. We agreed that it may be acceptable for professionals, with good reasons, to opt out of resuscitation attempts and these should be reflected on and discussed before the event.
Heterogeneity in the Continuity and Change of Early and Adult Risk Factor Profiles of Incarcerated Individuals: A Latent Transition Analysis
Authors: Fox Bryanna , Kortright Kelly , Gill Lexi , Mora Daniela Oramas , Moule Richard K. , Verona Edelyn 
Published: July 2020

Considerable research has examined risk factors for offending, but far less is known on the constellations of co-occurring risk factors, such as adverse childhood experiences and low self-control, and the overall continuity in risk between childhood/adolescence and adulthood. Using data on 735 adults incarcerated in a county jail in Florida, this study examines the latent heterogeneity in risk profiles using risk factors prominent in early years and adulthood, and whether risk profile severity changes across the early and adult risk models. Latent Class Analyses revealed three risk profiles (low, medium, high) in both the early and adulthood risk factor models. Transition probabilities indicate continuity in high and low risk in the early and adult models, while escalation was found for those in the low and medium early risk profiles. These findings demonstrate the importance of identifying and addressing risk factors at an early age to disrupt continuity and escalation in risk over the life-course.
Comparison of the effect of clarithromycin triple therapy with or without N-acetylcysteine in the eradication of Helicobacter pylori: a randomized controlled trial
Authors: Chen Chieh-Chang , Luo Jiing-Chyuan , Fang Yu-Jen , Lee Ji-Yuh , Kuo Chia-Chi , Yang Tsung-Hua , Chiu Min-Chin , Yu Jian-Jyun , Bair Ming-Jong , Chen Po-Yueh , Chou Chu-Kuang , Chen Chi-Yi , Chang Chi-Yang , Hsu Yao-Chun , Tseng Cheng-Hao , Hsu Wen-Feng , Hu Wen-Hao , Tsai Min-Horn , Hsieh Cheng-Lin , Chen Mei-Jyh , Shun Chia-Tung , Liu Tzeng-Ying , Lee§ Yi-Chia , Liou§ Jyh-Ming , Wu§ Ming-Shiang ,   and for the Taiwan Gastrointestinal Disease and Helicobacter Consortium
Published: July 2020

Background: Whether adjunctive N-acetylcysteine (NAC) may improve the efficacy of triple therapy in the first-line treatment of Helicobacter pylori infection remains unknown. Our aim was to compare the efficacy of 14-day triple therapy with or without NAC for the first-line treatment of H. pylori. Material and methods: Between 1 January 2014 and 30 June 2018, 680 patients with H. pylori infection naïve to treatment were enrolled in this multicenter, open-label, randomized trial. Patients were randomly assigned to receive triple therapy with NAC [NAC-T14, dexlansoprazole 60 mg four times daily (q.d.); amoxicillin 1 g twice daily (b.i.d.), clarithromycin 500 mg b.i.d., NAC 600 mg b.i.d.] for 14 days, or triple therapy alone (T14, dexlansoprazole 60 mg q.d.; amoxicillin 1 g b.i.d., clarithromycin 500 mg b.i.d.) for 14 days. Our primary outcome was the eradication rates by intention to treat (ITT). Antibiotic resistance and CYP2C19 gene polymorphism were determined. Results: The ITT analysis demonstrated H. pylori eradication rates in NAC-T14 and T14 were 81.7% [276/338, 95% confidence interval (CI): 77.5–85.8%] and 84.3% (285/338, 95% CI 80.4–88.2%), respectively. In 646 participants who adhered to their assigned therapy, the eradication rates were 85.7% and 88.0% with NAC-T14 and T14 therapies, respectively. There were no differences in compliance or adverse effects. The eradication rates in subjects with clarithromycin-resistant, amoxicillin-resistant, or either clarithromycin/amoxicillin resistant strains were 45.2%, 57.9%, and 52.2%, respectively, for NAC-T14, and were 66.7%, 76.9%, and 70.0%, respectively, for T14. The efficacy of NAC-T14 and T14 was not affected by CYP2C19 polymorphism. Conclusion: Add-on NAC to triple therapy was not superior to triple therapy alone for first-line H. pylori eradication [ClinicalTrials.gov identifier: NCT02249546].
Visitor’s Experiences of an Evidence-Based Designed Healthcare Environment in an Intensive Care Unit
Authors: Sundberg Fredrika , Fridh Isabell , Lindahl Berit , Kåreholt Ingemar 
Published: July 2020

Objectives: The objective of the research was to study the visitors’ experiences of different healthcare environment designs of intensive care unit (ICU) patient rooms. Background: The healthcare environment may seem frightening and overwhelming in times when life-threatening conditions affect a family member or close friend and individuals visit the patient in an ICU. A two-bed patient room was refurbished to enhance the well-being of patients and their families according to the principles of evidence-based design (EBD). No prior research has used the Person-centred Climate Questionnaire—Family version (PCQ-F) or the semantic environment description (SMB) in the ICU setting. Methods: A sample of 99 visitors to critically ill patients admitted to a multidisciplinary ICU completed a questionnaire; 69 visited one of the two control rooms, while 30 visited the intervention room. Results: For the dimension of everydayness in the PCQ-F, a significantly better experience was expressed for the intervention room ( p < .030); the dimension regarding the ward climate general was also perceived as higher in the intervention room ( p < .004). The factors of pleasantness ( p < .019), and complexity ( p < 0.049), showed significant differences favoring the intervention room in the SMB, with borderline significance on the modern factor ( p < .061). Conclusion: Designing and implementing an enriched healthcare environment in the ICU setting increases person-centered care in relation to the patients’ visitors. This could lead to better outcomes for the visitors, for example, decreasing post-traumatic stress disorder symptoms, but this needs further investigations.
Diarrhea and associated factors among under-5 children in Ethiopia: A secondary data analysis
Authors: Fetensa Getahun , Fekadu Ginenus , Tekle Firew , Markos Jote , Etafa Werku , Hasen Tahir 
Published: July 2020

Objectives: Diarrhea is a major contributing factor for preventable childhood morbidity and death. Despite the occurrence of diarrhea is decreasing, its effect is increasing at an alarming rate among under-5 children particularly in developing countries. The survey was aimed to assess diarrhea and associated factors among children less than 5 years (0–59 months) in Ethiopia with nationally representative data. Methods: The data were extracted from the Ethiopian National Survey of 2016. A logistic regression model was undertaken to identify the contributing factors for childhood diarrhea. Variables with p < 0.05 were considered as independent predictors of childhood diarrhea. Results: From a total of 10,641 under-5 children, 5483(51.5%) were males and most of the children (62.3%) were above 24 months. About 10.2% had diarrhea 14 days before data collection, and the majority (93.1%) were born to married mothers. Receiving no treatment or advice for fever/cough (adjusted odd ratio (AOR) = 0.170, 95% confidence interval (CI): 0.139–0.208, p = 0.001), being permanent residence (AOR = 0.583, 95% CI: 0.347–0.982, p = 0.043), initiating breastfeeding after 24 h of birth (AOR = 1.553, 95% CI: 1.197–2.015, p = 0.001), and lack of prenatal care (AOR = 2.142, 95% CI: 0.624–0.875, p = 0.001) were independent predictors of diarrhea among under-5 children’s in Ethiopia. Conclusion: The result of this survey indicated that diarrhea is a significant health challenge among under-5 children. To tackle this illness, sufficient education on child and maternal health has to be provided for mothers focusing on predictive factors.
Evaluation of radiologist’s knowledge about the Artificial Intelligence in diagnostic radiology: a survey-based study
Authors: Tajaldeen Abdulrahman , Alghamdi Salem 
Published: July 2020

Background Advanced developments in diagnostic radiology have provided a rapid increase in the number of radiological investigations worldwide. Recently, Artificial Intelligence (AI) has been applied in diagnostic radiology. The purpose of developing such applications is to clinically validate and make them feasible for the current practice of diagnostic radiology, in which there is less time for diagnosis. Purpose To assess radiologists’ knowledge about AI’s role and establish a baseline to help in providing educational activities on AI in diagnostic radiology in Saudi Arabia. Material and Methods An online questionnaire was designed using QuestionPro software. The study was conducted in large hospitals located in different regions in Saudi Arabia. A total of 93 participants completed the questionnaire, of which 32 (34%) were trainee radiologists from year 1 to year 4 (R1–R4) of the residency programme, 33 (36%) were radiologists and fellows, and 28 (30%) were consultants. Results The responses to the question related to the use of AI on a daily basis illustrated that 76 (82%) of the participants were not using any AI software at all during daily interpretation of diagnostic images. Only 17 (18%) reported that they used AI software for diagnostic radiology. Conclusion There is a significant lack of knowledge about AI in our residency programme and radiology departments at hospitals. Due to the rapid development of AI and its application in diagnostic radiology, there is an urgent need to enhance awareness about its role in different diagnostic fields.