bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abstract PO-004: Association between county-level socioeconomic characteristics and health indicators with COVID-19 deaths in Florida
Authors: Kiros Gebre-Egziabher , Gaddis Kira 
Published: December 2020

Abstract
COVID-19 has exposed the long standing racial health disparities and social inequities in the United States. It has also brought into focus the need of the vulnerable communities including racial and ethnic minority groups. health care reforms. The purpose of this analysis is to investigate county-level COVID-19 death rates with key socioeconomic and health indicators using correlation analysis. Death rates are calculated using deaths that occurred in Florida (n = 7,022 deaths) between March 1, 2020 and July 31, 2020. We hypothesize that counties with higher uninsured and older people have higher COVID-19 death rates. Data on COVID-19 county statistics is obtained from Florida Department of Health. County-level health indicators are obtained from Florida Health Community Health Assessment Resource Tool Set (CHARTS) and the County Health Rankings and Roadmap program of the Robert Wood Johnson Foundation. Spearman rank correlation, a non-parametric method, is applied to measure associations. We find that higher share of uninsured adults in a county is significantly associated with higher death rates from COVID-19. In addition, percent older than 65 is correlated death rates. However, contrary to other previous studies, we do not find a correlation between share of African Americans and death rates in Florida counties. Further, we do not find that death rates are correlated with measures of diabetes, smoking, and obesity. The policy implication of this investigation points to the vulnerability of communities without health insurance to the COVID-19 pandemic and the urgent need for health care reform. This research was supported by the National Institute on Minority Health and Health Disparities of the National Institutes of Health under the Award Number U54 MD007582. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. This research was also made possible by Grant Numbers U54CA233396, U54CA233444, & U54CA233465 from the National Institutes of Health (NIH), National Cancer Institute (NCI). Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NCI.
Citation Format: Gebre-Egziabher Kiros, Kira Gaddis. Association between county-level socioeconomic characteristics and health indicators with COVID-19 deaths in Florida [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-004.
Abstract PO-053: A culturally-sensitive and linguistically competent community-based hepatitis B and C intervention for underserved Asian American communities
Authors: Traub Kerry , Zhu Lin , Lu Wenyue , Ibrahim Safa , Yi Elizabeth , Wong Ada , Gonzalez Evelyn , Fraser Marilyn , Tan Yin , Ma Grace , Ogunwobi Olorunseun , Yeh Ming-Chin 
Published: December 2020

Abstract
Background The overall cancer rate is going down across the U.S., however liver cancer incidence is increasing, especially in Philadelphia. Approximately 70% of liver cancer cases are caused by hepatitis B and C virus (HBV and HCV). Notably, Asian Americans (AAs) are disproportionally affected by liver cancer with mortality rate 60% higher than that of non-Hispanic White. Methods We partnered with community-based organizations (CBOs) using community-based participatory research approach. CBOs were involved in all steps of the project, and co- developed/co-delivered community education to increase awareness of liver cancer prevention and screening in Philadelphia. 152 Asian American community members recruited from collaborating CBOs and participated in the educational workshops.
Demographic information and knowledge on HBV, HCV, and liver cancer were collected before and after the education. Statistical analysis of Chi-square and t-test were conducted to measure the education’s effect. Results Less than half of the participants rated their health condition as “good and above” (48.95%). With regard to liver cancer prevention awareness, less than one third of the participants had heard about HBV (31.58%) and HCV (21.05%) from their primary care providers, and even fewer of them ever got HBV (21.71%) and HCV (2.63%) testing. Participants’ knowledge increased significantly from the pre-test to the post-intervention evaluation (7.39 vs. 9.24, p&lt;0.001). Conclusions Our findings add to the growing body of evidence on the effectiveness of culturally sensitive and linguistically competent education intervention in raising awareness and increasing knowledge of cancer prevention in underserved communities. We will discuss the success and lessons learned regarding engaging community, participant recruitment, retention, and implementation strategies.
Citation Format: Kerry Traub, Lin Zhu, Wenyue Lu, Safa Ibrahim, Elizabeth Yi, Ada Wong, Evelyn Gonzalez, Marilyn Fraser, Yin Tan, Grace Ma, Olorunseun Ogunwobi, Ming-Chin Yeh. A culturally-sensitive and linguistically competent community-based hepatitis B and C intervention for underserved Asian American communities [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-053.
Abstract PO-054: Hepatitis B and C screening and knowledge of liver cancer in underserved Chinese American adults in New York City: A community-based assessment
Authors: Lu Wenyue , Traub Kerry , Ibrahim Safa , Yi Elizabeth , Wong Ada , Gonzalez Evelyn , Zhu Lin , Fraser Marilyn A. , Tan Yin , Ogunwobi Olorunseun , Ma Grace X. , Yeh Ming-Chin 
Published: December 2020

Abstract
Background Of all liver cancer cases detected in the United States, approximately 70% are caused by hepatitis B and C virus (HBV and HCV). Asian Americans (AAs) are disproportionally affected by liver cancer, with a mortality rate 60% higher than that of non-Hispanic White. In recent years the incidence rate of liver cancer in New York City has been 35% higher than the national average. Methods In New York City, we collaboratively developed and conducted a liver cancer prevention education with community-based organizations to increase awareness of liver cancer prevention and screening. Assessment data was collected from Asian American community members who participated in our educational workshops. Preliminary findings from 53 participants' knowledge on HBV, HCV, and liver cancer prior to the intervention, will be reported in this presentation. Chi-square and t-test were used to conduct data analysis. Results Almost half of the participants reported hearing about HBV (48.1%) and HCV (60.4%) from their medical team, and even fewer of them ever received HBV (37.7%) and HCV (9.4%) testing. Participants were knowledgeable on HBV/HCV transmission (scored 7.9 out of 10), they lack the knowledge on liver cancer risk factors (scored 1.9 out of 5). Those who were covered with health insurance were more knowledgeable on identifying risk factors of liver cancer than those uncovered (1.94 vs. 1.00, p&lt;0.001). Conclusions Our findings show that there is a pressing need for educational intervention, especially in New York City, to promote liver cancer interventions among at-risk Asian Americans.
Citation Format: Wenyue Lu, Kerry Traub, Safa Ibrahim, Elizabeth Yi, Ada Wong, Evelyn Gonzalez, Lin Zhu, Marilyn A. Fraser, Yin Tan, Olorunseun Ogunwobi, Grace X. Ma, Ming-Chin Yeh. Hepatitis B and C screening and knowledge of liver cancer in underserved Chinese American adults in New York City: A community-based assessment [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-054.
Abstract PO-065: Gauging U54 PACHE effectiveness through an analysis of publications
Authors: Behar-Horenstein Linda S. , Horenstein Max D. , Richey Joyce M. 
Published: December 2020

Abstract
What is known about the impact of PACHE can be assessed through varied evaluative methods. Describing the scope of center publications offers one type of insight.
Using document review, 963 publicly accessible NIH RePORT publications across the 16 funded U54 Partnerships to Advance Cancer Health Equity (PACHE) center programs were identified. The authors read each study and determined if it they met inclusion criteria: an evidence-based study that presented quantitative or qualitative results, a statement of purpose, overview of methods, presentation of results, and a discussion or conclusion section. Position papers and duplications were excluded from this review. Using the remaining 868 publications, the authors determined the frequency of publications across programs by longevity; reported the frequency of studies focused on cancer health disparities; determined the proportion of institutions serving underserved health disparity populations, underrepresented students (ISUPS) co- and lead-authored works; and categorized the scope of studies by commonalities in their reported purposes. Findings showed that: (1) center longevity was not necessarily related to the number of publications, (2) less than 20% of studies focused on cancer health disparities (CHD), (3) ISUPU co-authors appeared in 72% of publications while lead authors were 48%, (4) 6.07% publications focused on cancer diagnosis, screening, treatment, and risk factors; 57.50% studies were mechanistic; 21.53% focused on the impact of interventions on health promotion, prevention, and quality of life; 5.62% studies were related to educational outcomes; and 9.28% studies were classified as epidemiological/survey outcomes.
One of the primary purposes of PACHE centers is CHD research. Thus, we advocate increasing the frequency of CHD-focused publications. We also suggest increasing the number of ISUPU lead-authored papers. To align with the PACHE mission, we also recommend increasing the number of studies focused on cancer diagnosis, screening, treatment, and risk factors, and the impact of interventions on health promotion, prevention, and quality of life. To demonstrate the effectiveness and impact of training, increasing the number educational outcome studies is also proposed.
Citation Format: Linda S. Behar-Horenstein, Max D. Horenstein, Joyce M. Richey. Gauging U54 PACHE effectiveness through an analysis of publications [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-065.
Abstract PO-087: Anal cancer and its association with HPV16 lineage B in African Americans
Authors: Ashktorab Hassan , Laiyemo Adeyinka , Mirabello Lisa , Brim Hassan 
Published: December 2020

Abstract
Background: Human papillomavirus type 16 (HPV16) is one of the most common and carcinogenic HPV types associated with high risk of anal, vagina, vulva, penis and cervical neoplastic transformations. However, many genetic variants exist within this virus and not all seem to have the same carcinogenic potential. Aim: To determine HPV16 lineages and their association with risk of high-grade anal lesions in African Americans in an inner-city hospital. Methods: We reviewed medical records of 370 African Americans with anal lesions from Jan. 2007 to Dec. 2015. This study was approved by Howard University Institutional Review Board. Demographic, clinical and pathological data including HPV, HIV, HCV (hepatitis C virus), diabetes mellitus, hypertension and body mass index (BMI) were collected. DNA was extracted from a subset of HPV16-positive patients with FFPE tissue samples (72 patients, 111 samples) and used for HPV16 whole-genome sequencing. We assessed HPV16 variant lineages and associations with disease stage. Statistical analyses were performed using Chi-square tests, Student’s t-tests, and logistic regression. Odds ratios (OR) and p-values were calculated for comparisons of normal/condyloma/high-grade dysplasia (HGD) vs. squamous cell carcinoma (SCC) and for normal/condyloma vs. HGD. The most common HPV16 A1 sublineage was used as a reference in these comparisons. Results: Males represented 75% of the patients (n=276), with a median age of 44 years and BMI of 25.8 kg/m2. The frequency of condyloma, high-grade dysplasia, SCC and adenocarcinoma was 191 (52%), 26 (7%), 31 (8%) and 8 (2%), respectively. The frequency of HPV, HIV, and HCV was 231 (68%), 147 (43%) and 42 (12%), respectively. HPV and HIV were risk factors for condyloma and dysplasia (P&lt;0.05). All four main lineages of HPV16 (A,B,C,D) were detected in our specimens, with sublineage A1 most common. Lineage B, also named the African-1 HPV16 lineage because it is most common in Africa, had the strongest association with SCC (OR=10.5) whether alone or in combination with lineages A4 and D (OR=10.5), although with a lower statistical significance (0.054 vs. 0.009). As for HGD, lineage B along with A4, C and D only gave an OR of 1.4. Conclusion: We show that the majority of patients with anal lesions are young males with HPV and HIV co-infections. HPV16 lineage B was associated with a high risk of SCC development.
Citation Format: Hassan Ashktorab, Adeyinka Laiyemo, Lisa Mirabello, Hassan Brim. Anal cancer and its association with HPV16 lineage B in African Americans [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-087.
Abstract PO-123: Disparities in optimal treatment of oral and pharyngeal cancers by ethnicity and smoking status
Authors: Fechtel Hannah J. , Guo Yi 
Published: December 2020

Abstract
Oral and Pharyngeal Cancer (OPC) is a deadly cancer with complex treatment plans and outcomes. In practice, surgery followed by radiation or chemotherapy is considered the “optimal treatment” associated with better OPC survival. However, not all OPC patients receive the optimal treatment. Prior research has documented that survival varies by smoking status and ethno-racial groups, but little is known about the relationship between a patient’s smoking status, ethnicity, and the choices they make about cancer treatment post diagnosis. To shed light on this under- studied issue, data from the Florida Cancer Data System were analyzed. A logit model was built with the response variable treatment pattern arranged into three levels: surgery only (reference), surgery followed by radiation or chemotherapy, and other treatment types. The predictors included smoking status, race-ethnicity, smoking by race-ethnicity interaction, health insurance, age at diagnosis, gender, and marital status. Overall, the odds of receiving optimal treatment for Non-Hispanic Whites and Non-Hispanic Blacks are 29%-34% (p&lt;0.001) greater than the odds of optimal treatment for Hispanics. One significant smoking by race-ethnicity interaction was found between Non-Hispanic Blacks and current smoking status, making Non-Hispanic Blacks who currently smoke less likely to receive optimal treatment than those who do not smoke.
Citation Format: Hannah J. Fechtel, Yi Guo. Disparities in optimal treatment of oral and pharyngeal cancers by ethnicity and smoking status [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-123.
Abstract PO-141: Dietary and cultural practices of minorities in New York City as an indicator of colorectal cancer screening behavior and screening intent
Authors: Johnson Cicely K. , Ogunwobi Olorunseun , Ma Grace 
Published: December 2020

Abstract
There are significant racial and gender disparities in health behaviors and health outcomes in the United States, and these differences are vast and not well understood. As colorectal cancer is the third most common cancer diagnosed in both men and women in the United States, and African-Americans have the highest colorectal cancer incidence and mortality rates of all the racial groups in the U.S., it is essential to understand the interplay between individual health behaviors that may be unique racial patterns and health outcomes. This research study is a pilot study that is part of a larger study with existing preliminary data. This pilot study examined dietary habits and practices of individuals of individuals identifying as Black as a predictor for colorectal cancer screening. The linkages between race and health behaviors have been the subject of research, however much work remains to improve understanding of factors associated with preventive cancer screening and the differences by race and within race. This study addresses the relationship between dietary habits and screening behavior and intent. Comparisons will be explored through the lenses of ethnicity and gender. To address the significant gap in literature, survey data was collected on dietary habits and screening behavior (most recent exam and intent to screen within a year) from 500 individuals in the boroughs of New York City. Participants are those who identify as Black and are from multiple ethnicities. This study evaluates the correlation between individuals with a higher intake of healthy options, and their intent to screen for colorectal cancer within a year. This study utilizes a survey tool that includes a modification of the Eating Habits Questionnaire of the Dana Farber Cancer Institute, blended with a modification of the Motivators of and Barriers to Health-Smart Behaviors inventory (MB-HSBI).
Future work of this study is concerned with gathering qualitative data around the interrelationship between culture and diet as it pertains to screening behavior and intent, and the multiple variations of that relationship by ethnicity. Results of these studies can provide health educators, providers, and policy makers information that is critically in an effort to create culturally relevant health promotion materials within the Black community.
Citation Format: Cicely K. Johnson, Olorunseun Ogunwobi, Grace Ma. Dietary and cultural practices of minorities in New York City as an indicator of colorectal cancer screening behavior and screening intent [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-141.
Abstract PO-154: Establishing the prevalence of high-risk HPV infection and identifying associated risk factors in Santo Domingo, Ecuador
Authors: Foster Hanna , Alexandrova Maria , Ghiaseddin Roya , Gaus David , Taylor Katherine , Larco Danny , Stack Sharon 
Published: December 2020

Abstract
Human papillomavirus is a common sexually transmitted infection that affects men and women. For women, persistent infection with high-risk HPV genotypes is a significant risk factor for cervical cancer, and HPV infection is more prevalent in developing countries than in developed countries. Furthermore, women in developing countries experience a greater number of cervical cancer cases attributable to HPV infection than women in developed countries. In Ecuador, recent studies have shown an increased prevalence of high-risk HPV genotypes in certain regions, specifically Quito and in Southern Ecuador. No study has analyzed the prevalence of high-risk HPV in Santo Domingo, Ecuador. In this quantitative study, the prevalence of high-risk HPV in Santo Domingo was determined by analyzing cervical cytology samples taken from pregnant women visiting three local health clinics. Women younger than 18 years of age were excluded. The study also analyzed associated risk factors for infection. Overall, 24.1% of participants tested positive for high-risk HPV infection. Genotypes falling into the “other high risk” category (i.e. HPV- HPV-31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68) were the most prevalent. This result differed slightly from findings in comparable studies completed in Ecuador where HPV-16 was found to be most prevalent among the study population. Age and Pap smear history were independently determined to be significant predictors of HPV status. These findings indicate the significance of routine female wellness and gynecological screenings at Saludesa Hospital, and Augusto Egas and Santa Martha clinics. Furthermore, results also emphasize the importance of vaccine use as primary prevention measures against HPV infection in adolescents in Santo Domingo. Currently, Saludesa Hospital, Augusto Egas and Santa Martha clinics do not offer vaccinations for protection against HPV infection. However, girls between ages of 11 and 12 seeking care at these facilities would likely benefit from preventive reproductive health care, including access to vaccinations, to protect against high- risk HPV infection. Education regarding the epidemiology of high-risk HPV infection could enhance the public’s acceptance of screening and intervention programs.
Citation Format: Hanna Foster, Maria Alexandrova, Roya Ghiaseddin, David Gaus, Katherine Taylor, Danny Larco, Sharon Stack. Establishing the prevalence of high-risk HPV infection and identifying associated risk factors in Santo Domingo, Ecuador [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-154.