bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variation in ACL and MCL Strain Before Initial Contact Is Dependent on Injury Risk Level During Simulated Landings
Authors: Bates Nathaniel A. , Schilaty Nathan D. , Krych Aaron J. , Hewett Timothy E. 
Published: November 2019

Background: The existent literature has well explored knee ligament kinetics and strain at and after initial contact (IC) during landing tasks. However, little is known about knee ligament biomechanics in flight before IC. Purpose: To quantify and compare change in anterior cruciate ligament (ACL) and medial collateral ligament (MCL) strain before IC relative to after IC. Study Design: Descriptive laboratory study. Methods: A total of 40 cadaveric specimens were analyzed after being subjected to simulated landings in a mechanical impact simulator. External joint loads of varying magnitudes were applied to mimic relative injury risk load levels from an in vivo cohort and were coupled with an impulse force to represent initial ground contact. Implanted strain gauges continually recorded ligament strain. Kruskal-Wallis tests evaluated the significance of risk level and pre- and post-IC factors, while Wilcoxon each-pair tests evaluated differences within both factors. Results: Strain responses during simulated landing tasks for the ACL ( P ≥ .545) and MCL ( P ≥ .489) were consistent after IC regardless of the level of relative injury risk simulated in each trial. Before IC, the level of injury risk kinetics applied to a specimen differentiated strain response in the ACL ( P < .001) and MCL ( P < .001), as higher risk profiles produced greater changes in ligament strain. Mean baseline strain was 4.0% in the ACL and 1.0% in the MCL. Mean change in strain from the ACL ranged from 0.1% to 3.9% pre-IC and from 2.9% to 5.7% post-IC, while the MCL ranged from 0.0% to 3.0% pre-IC and from 0.9% to 1.3% post-IC. Conclusion: Within each ligament, post-IC strain response lacked statistical differences among simulated risk profiles, while pre-IC response was dependent on the risk profile simulated. Individually, neither pre- nor poststrain changes were enough to induce ACL failure, but when combined over the course of a full landing task, they could lead to rupture. Clinical Relevance: Prevention and rehabilitation techniques should aim to limit the presence of increased risk biomechanics in flight before landing, as impulse delivery at IC is inevitable.
Tendon of Achilles (TA) Repair: “This is How I Do It”
Authors: Eufemio Edgar Michael T. 
Published: November 2019

A torn TA is a devastating injury and majority of the cases are sports-related. Several procedures have been developed over the years and these have continued to evolve. The keys to a successful outcome are still the same: A Thorough Physical Examination A Sound Surgical Technique Strong Suture Material A Good Physical Therapy Program I would like to present a method I have been using for the past twenty years. Only the post-op rehabilitation course has changed. In 2008, I drastically changed my system after surgery. The highlights are the following: Full Weight Bearing Started Immediately with a Cast Boot Active Range of Motion Allowed as Tolerated Stretching Exercises Started After 4 Weeks Strengthening Program Started After 6 Weeks Running, Trampoline Exercises and Sports-Specific Drills After 3 Months Back to Sports After 4 Months
Arthroscopic Lateral Ligament Repair
Authors: Lee Jin Woo 
Published: November 2019

Ankle sprain is one of the most common sports-related injuries and involves the three ligaments of the lateral ligament complex of the ankle. Approximately 80% of patients tear the anterior talo-fibular ligament (ATFL), while the other 20% of patients tear the ATFL and calcaneo-fibular ligament (CFL). Rarely, the posterior talo-fibular ligament (PTFL) is involved. Non-surgical management of ankle sprains leads to excellent results in most cases for the initial phase. An incidence of 10 – 30% of patients would fail conservative treatment and result in chronic lateral ankle instability (CLAI) that may require surgical intervention. And the CLAI is commonly associated with other lesions, such as osteochondral lesion, soft tissue impingement syndrome, loose body, and peroneal tendon disorder so that diagnostic arthroscopy is mandatory with stabilizing lateral ankle. Although more than 50 surgical procedures have been described for stabilizing the lateral ankle ligaments complex. The original technique of Broström, modified by Gould, has become the gold standard procedure with infrequent exception in the literatures. However, the open technique requires at least a 4-cm-long incision with significant dissection and soft tissue debridement. Recently, there has been a recent advent of published descriptions on arthroscopic procedures for CLAI with advanced anatomic and bio-mechanic researches of lateral ankle ligaments complex. As in other minimal invasive surgical techniques in the foot and ankle, arthroscopic lateral ligament repair has advantages of less pain, addressing intra-articular pathologies, less injury to surrounding tissue, faster recovery, shorter hospital stay, and better cosmetic result. However, there are concerns about this new emerging technique with a technically demanding and lack of long-term clinical results. The purpose of this presentation is to review what has been established for the CLAI and discuss the arthroscopic lateral ligament repair technique.
Remnant Preserving or Augmentation SB PCL Reconstruction: Tips and Tricks
Authors: Nelwan Bobby Natanel 
Published: November 2019

Injury to the Posterior Cruciate Ligament (PCL) is thought to account for 3% to 20% of all knee ligament injuries. Accurate diagnosis of the PCL injury is the first step in determining appropriate management. Approximately 60% of PCL injuries are associated with tearing of the Posterolateral Corner (PLC) structures. When the surgery, arthroscopy PCL reconstruction, is decided then we have to think how and what the best technique will be used to reconstruct. Various techniques of PCL Reconstruction Arthroscopy are known that based on research. According the position of PCL, the procedure of reconstruction is more difficult than ACL one. If combined with PLC rupture, all the structures will be reconstructed in one step. Will be proposed the tips and tricks how to do arthroscopy remnant preserving or augmentation single bundle PCL reconstruction, such as: how to preserve the remnant, how to find the position of tibial attachment and what the landmark, how to deliver the graft into the tunnels so preventing “killer turn” on the posterior part of joint, and how to do the proper rehabilitation. By using the Posterior Medial Portal, working with Remnant Preserved of PCL Reconstruction will be made easier. Joint line of medial tibial plateau as a landmark to find the tibial tunnel. About 1.5 cm below the joint line, the point of tibial tunnel is made or directly finding the edge of the ‘shelf’ where the tunnel is made on there. The remnant will be split and the graft will be laid in between. A strong suture material is used to pull the graft with all in side technique. The tibial part of the graft goes in first through the anterolateral portal following the suture material, go into between the remnant and go into the tibial tunnel from posterior to anterior (inside out). The femoral part of the graft will go into the joint together with the wire that carrying the distal end of the graft go into the femoral tunnel. After that we make the finalization of procedure. Finally, a special rehab program is needed to get the good result of PCL reconstruction as a whole.
Which Stretching Method is Superior in Plantar Fasciosis?
Authors: Butarbutar John 
Published: November 2019

Plantar fasciosis is prevalent in orthopedic clinic particularly foot and ankle sections. First-line treatment includes rest, non-steroidal anti-inflammatory drugs, orthotics, and stretching. However, approximately 10-40% of patients will have persistent symptoms after 2 years. Several stretching methods have been proposed, targeting plantar fascia and calf muscle. Plantar fascia specific stretching alone showed superior result in short-term follow up only, compare to calf muscle stretching, but combine stretching effectiveness is still inconclusive. The practical conclusion is difficult to draw because foot arch type and leg flexibility are not included in those stretching studies. We believe that the possible benefit of combined stretching benefits should not be overlooked, especially in patients with a high arch or tight calf muscles. In our opinion, future studies of plantar fasciosis and stretching should include foot type and lower extremity flexibility.
Clinical Outcomes of Revision Meniscal Repair
Authors: Sakti Muhammad 
Published: November 2019

Background: The failure rate after arthroscopic primary meniscal repair ranges from 5% to 43.5% (mean 15%). Patients requiring revision surgery may benefit from revision meniscal repair, however, the results of this procedure remain underreported. Objective: This was a retrospective study aim to evaluate the outcome of revision meniscal repair in patients with re-tears in Makassar’s hospitals from 2010 – 2017. Methods: A medical record review was performed to identify all patients undergoing revision meniscal repair between 2010 and 2017 in Makassar’s hospitals. Only patients with re-tears of the primary repaired meniscus were included. Surgical technique of primary and revision meniscus repair was detailed. The records of all patients were reviewed to collect patient demographics, affected side of the re-teared meniscus, reasons for failed primary repair, combined disorder, location of the tear, and duration between the primary and revision surgery. Follow-up evaluation included clinical outcome scores (Lysholm Score). Results: A total 9 of 15 patients (5 male and 4 female) with a mean age of 25.3 years (range, 19 to 44) and a mean BMI of 24.48 kg/m2 (range, 19.6 to 32.9) were included. Three lateral menisci and six medial meniscal repairs were revised at mean 23.3 months (range, 19 to 32) after primary repair. Reasons for failed primary repairs were traumatic re-tears in 4 patients (44%) and non-traumatic re-tears in 5 patients (56%). Patients undergoing isolated meniscal repair were found in 6 patients, 2 patients with ACL concomitant disorder, and 1 patient with osteoarthritis. Two tears occurred in the red-red zone and 7 in the red-white zone. At final follow-up, the mean Lysholm score significantly improved from 79.8 points (range, 75-84 points) at pre-revision to 88.1 (range, 80 to 97). Conclusion: Meniscal repair should always be considered when the anatomic conditions are favorable (location, type of tear, ACL status).
Comparison Effect of Corticosteroid Injection with Low Level Laser Therapy in Plantar Fasciitis Patients in Dr. Bratanata Hospital, Jambi
Authors: Simanjuntak Charles A , Gading Patrick W 
Published: November 2019

Objectives: Plantar fasciitis is a common pain disorder that affects the heel and soles of the feet. These are abnormalities at the location of tendon insertions in the bone and are characterized by scarring, inflammation, or damage to the plantar fascia. Treatment options for patients with plantar fasciitis vary with little consensus on the clinical approach. Physical therapy procedures including LLLT (Low-Level Laser Therapy) are most often applied in conservative treatment of plantar fasciitis. While steroid injection is a treatment that has been proven effective in the management of short-term symptoms. The aim of this study was to compare the effects of LLLT and steroid injection on pain and functional conditions in patients with plantar fasciitis. Methods: This is a prospective study conducted in 30 patients. 15 patients were treated with local injection steroids (single Group A) and 15 patients were treated with LLLT (Group B), 8 J / cm2 per day, 3 days per week for 2 weeks. VAS scores and FFI (Foot Function Index) are measured. Results: Pain intensity was reduced in both groups after 2 weeks. VAS scores decreased to 3.47 in Group A and 3.82 in Group B in 2 weeks (p <0.05). In Group A, FFI decreased to 22.03 ± 4.45 while in Group B it decreased to 26.40 ± 2.52 in the same interval. But generally, patients who suffer from plantar fasciitis prefer LLLT compared to more invasive steroid injection therapy. Conclusion: LLLT therapy and steroid injection are effective methods for reducing pain and improving foot function in plantar fasciitis. It appears that steroid injection is superior to LLLT therapy. But fear of invasive action, patients have LLLT.
Extensive Lateral Release and Medial Patello-femoral Ligament Reconstruction in 25 years of Chronic Fixed Lateral Patellar Dislocation: A 5 year follow up Case Report
Authors: Lubis Andri , Aprianto Petrus , Siregar Yudistira P. 
Published: November 2019

Objectives: Chronically fixed lateral patellar dislocation is uncommon and mostly associated with disruption of the medial patellofemoral ligament (MPFL) which is a major risk factor for this condition, as it functions as the main patella medial stabilizer. This paper focuses on the reconstruction of the MPFL after an extensive lateral release in a fixed lateral patellar dislocation. We aim to explain the technique that was used to reduce and maintain the position of the patella and prevent it from re-dislocation. Extensive lateral release and modified MPFL reconstruction for a chronically fixed patellar lateral dislocation provide a satisfactory result. We aim to explain a modified technique to treat a chronically fixed patellar lateral dislocation Case presentation: We present a case report of a 49-year-old Caucasian male with a history of falling on his right knee 25 years before. He complained of pain on his knee for 8 months before. Physical examination showed chronically fixed lateral patellar dislocation with a normal range of motion. The diagnosis of patellar dislocation was confirmed with a conventional radiograph. The patient underwent extensive lateral release of the knee followed by a modified technique for MPFL reconstruction. Semitendinosus tendon was used as the graft because of the chronic nature of this condition. The graft was inserted into the patellar tunnel and fixed using endobutton®. The graft was inserted into the femoral tunnel that was made at Schottle point from the medial through the lateral side. After that, the cortical screw with the washer was inserted on the lateral femoral side just above the femoral tunnel as an anchor to make sure the tendon is secured. We follow-up the patient for 5 years. Results and Conclusion: On a 5 year follow-up, there was no complaint of recurrent patellar dislocation. The result of this extensive lateral release followed by modified MPFL reconstruction for a chronically fixed lateral patellar dislocation is satisfactory. The extensive release was needed to reduce the fixed dislocated patella and this modified technique of MPFL reconstruction by using screw and washer as an anchor on lateral sides of the femur could be an alternative to prevent re-dislocation.
Acute Symptoms on Rotator Cuff Calcific Tendinitis is Effectively Relieved by Ultrasound Guided Percutaneous Needle Lavage Procedure: a Case Report
Authors: Mandagi Tommy , Sindunata Nyoman Aditya , Suvarly Prettysia , Butarbutar John 
Published: November 2019

Introduction: Rotator cuff calcific tendinitis (RCCT) frequently manifests as acute shoulder pain during the acute resorptive phase. Pain typically worse at night and limited range of motion (ROM) with muscle spasm. Several treatment options have been proposed. In this case, a single needle ultrasound-guided percutaneous lavage (UGPL) combined with corticosteroid subdeltoid bursa injection (SDBI) with a good outcome. Case Presentation: A Female, 59 years old, presents with left RCCT acute pain (VAS 7/10) for 2 days and limited painful shoulder ROM. Inflammation and local tenderness found on the left shoulder, ultrasonography shows calcification in the left infraspinatus tendon with sub-deltoid bursa fluid. Patient in sitting position, ultrasound probe placed at long axis of infraspinatus tendon. Using a 23G needle 5 ml syringe, 1% lidocaine infiltrated until the needle penetrates the calcification site. Then a small amount of normal saline (NaCl) with lidocaine injected in a pulsating manner, observed until chalky matter backflows, mixed with NaCl in the syringe. Repeat this procedure until chalky backflow is minimal. Finally, 10 ml of Triamcinolone Acetonide 40 mg mixed with 2 ml lidocaine 2% SDBI using the same needle. Dramatic shoulder pain relieve (VAS 2/10) is immediately achieved after the procedure. One week follow up, the patient is pain-free and regains full ROM of her left shoulder. Discussion: Several methods are proposed for the treatment of acute RCCT, including corticosteroid injection and arthroscopy debridement. UPGL is an attractive option because it is minimally invasive, can be performed in-office setting, and pain relief is obtained immediately by decompressing and removing inflamed calcified sites. Conclusion: The treatment in acute pain RCCT using UGPL combined with corticosteroid SDBI provides a good outcome.
Oral Investigation in Childhood Psoriasis: Correlation With Geographic Tongue and Disease Severity
Authors: Lavinas Sayed Bruna Picciani , Teixeira-Souza Thays , Almenara Áquila Curty , Azulay-Abulafia Luna , Hertz Amanda , Mósca-Cerqueira Ana Maria , Chigres Fabio Kuschnir , Milagres Adrianna , Pedra-Dias Eliane 
Published: November 2019

Background: Childhood psoriasis affects 2% of the world pediatric population. An association between psoriasis and geographic tongue (GT) in adults has been suggested, but there are no studies in children. Objective: This study aimed to compare the prevalence of oral lesions in pediatric patients with psoriasis (PP) and healthy controls and investigate the correlation between GT, severity, and age of psoriasis onset. Methods: The participants were 17 PP aged <18 years and 91 HC. The severity of vulgaris psoriasis was determined according to Psoriasis Area and Severity Index (PASI) and all patients underwent an oral examination. Results: Oral findings were present in 43% of the participants and the most common lesions were candidiasis and GT. There was a mean earlier onset in psoriasis with GT (3 years old) compared to psoriasis without GT (10 years old). The mean PASI scores in psoriasis with GT and psoriasis without GT were 9 and 3, respectively. Conclusion: Geographic tongue and candidiasis were frequently found in PP. Patients with psoriasis with GT are younger and have earlier onset of the disease, a positive family history of psoriasis, and a severe form of the disease. The present study is the first of its type to demonstrate clinical differences in pediatric PP with and without GT.
Genome-wide Profiling of Histone Lysine Butyrylation Reveals its Role in the Positive Regulation of Gene Transcription in Rice
Authors: Liu Shuai , Liu Guanqing , Cheng Peifeng , Xue Chao , Zhou Yong , Chen Xu , Ye Lu , Qiao Zhongying , Zhang Tao , Gong Zhiyun 
Published: November 2019

AbstractBackgroundHistone modifications play important roles in growth and development of rice (Oryza sativaL.). Lysine butyrylation (Kbu) with a four-carbon chain is a newly-discovered histone acylation modification in rice.Main BodyIn this study, we performed chromatin immunoprecipitation sequencing (ChIP-seq) analyses, the result showed that major enrichment of histone Kbu located in genebody regions of rice genome, especially in exons. The enrichment level of Kbu histone modification is positively correlated with gene expression. Furthermore, we compared Kbu with DNase-seq and other histone modifications in rice. We found that 60.06% Kub enriched region co-located with DHSs in intergenic regions. The similar profiles were detected among Kbu and several acetylation modifications such as H3K4ac, H3K9ac, and H3K23ac, indicating that Kbu modification is an active signal of transcription. Genes with both histone Kbu and one other acetylation also had significantly increased expression compared with genes with only one acetylation. Gene Ontology (GO) enrichment analysis revealed that these genes with histone Kbu can regulate multiple metabolic process in different rice varieties.ConclusionOur study showed that the lysine butyrylation modificaiton may promote gene expression as histone acetylation and will provide resources for futher studies on histone Kbu and other epigenetic modifications in plants.
Local origin or external input: modern horse origin in East Asia
Authors: Ning Tiao , Ling Yinghui , Hu Shaoji , Ardalan Arman , Li Jing , Mitra Bikash , Chaudhuri Tapas Kumar , Guan Weijun , Zhao Qianjun , Ma Yuehui , Savolainen Peter , Zhang Yaping 
Published: November 2019

Abstract
Background
Despite decades of research, the horse domestication scenario in East Asia remains poorly understood.

Results
The study identified 16 haplogroups with fine-scale phylogenetic resolution using mitochondrial genomes of 317 horse samples. The time to the most recent common ancestor of the 16 haplogroups ranges from [0.8–3.1] thousand years ago (KYA) to [7.9–27.1] KYA. With combined analyses of the mitochondrial control region for 35 extant Przewalski’s horses, 3544 modern and 203 ancient horses across the world, researchers provide evidence for that East Asian prevalent haplogroups Q and R were indigenously domesticated or they were involved in numerous distinct genetic components from wild horses in the southern part of East Asia. These events of haplotypes Q and R occurred during 4.7 to 16.3 KYA and 2.1 to 11.5 KYA, respectively. The diffusion of preponderant European haplogroups L from west to East Asia is consistent with the external gene input. Furthermore, genetic differences were detected between northern East Asia and southern East Asia cohorts by Principal Component Analysis, Analysis of Molecular Variance test, the χ2 test and phylogeographic analyses.

Conclusions
All results suggest a complex picture of horse domestication, as well as geographic pattern in East Asia. Both local origin and external input occurred in East Asia horse populations. And besides, there are at least two different domestication or hybridization centers in East Asia.