bluuebunny/crossref_metadata_2025_split huggingface dataset:
Religiöses Coping bei einer lebensbedrohlichen Krankheit im Vergleich zu anderen Bewältigungsformen
Authors: Seidl Otmar , Frick Eckhard 
Published: October 2020

Zusammenfassung
Spiritualität und religiöses Coping bei lebensbedrohlichen Krankheiten finden zunehmendes wissenschaftliches und praktisches Interesse im Sinne des Spiritual Care. Widersprüchlich sind allerdings die Aussagen über die Effekte dieser Bewältigungsform. Am Modell der HIV-Infektion als einer lebensbedrohlichen Krankheit in der Zeit vor Einführung der antiretroviralen Kombinationstherapie wurden die Häufigkeit und der Erfolg des religiösen Copings untersucht.
105 HIV-infizierte Männer und Frauen (55 Homosexuelle, 30 Hämophile und 20 Drogenkonsumenten) wurden in einem sozialpsychologisch-tiefenpsychologischen Interview über ihre Krankheitsbewältigung befragt. Die Auswertung hinsichtlich des religiösen Copings neben anderen Bewältigungsmechanismen erfolgte im Fremdrating mittels der Berner Bewältigungsformen nach Heim et al. (1990). Das Bewältigungsergebnis wurde mittels des Beeinträchtigungs-Schwere-Scores nach Schepank (1995) bestimmt.
25 % der Probanden, darunter fast nur Homosexuelle, hatten ein intensives und der Rest überwiegend kein religiöses Coping. Religiöses Coping führte zu keinem besseren Ergebnis als andere Mechanismen und wurde nicht vom Krankheitsstadium beeinflusst. Religiöses Coping war eng verknüpft mit einem internalen locus of control. Kein Zusammenhang fand sich mit Alter, Religionszugehörigkeit, Sozialschicht und Schuldphantasien.
Religiöses Coping scheint eine relativ unabhängige stabile Verhaltensdisposition zu sein, die mit dem Gefühl der Eigenverantwortlichkeit verknüpft ist. Religiöse bzw. spirituelle Bedürfnisse sollten, falls vorhanden, bei der psychosozialen Betreuung der Patienten unterstützend berücksichtigt werden.
Plural marking on noun-associated forms
Authors: Di Garbo Francesca 
Published: October 2020

AbstractNumber systems can be morphosemantic or morphosyntactic, based on whether number marking is restricted to nouns or also extends to noun-associated forms, such as adnominal modifiers, predicates, and pronouns. While it is well-known that asymmetries in the distribution of plural marking on nouns can be due to lexico-semantic properties such as animacy and/or inherent number, the question of whether these properties also affect patterns of plural agreement has been less broadly investigated. This paper examines the distribution of plural agreement in 24 Cushitic (Afro-Asiatic) languages. The number systems of the languages of the sample are classified into three types, ranging from radically morphosemantic (Type 1) to radically morphosyntactic (Type 2). A subset of languages displays a combination of morphosemantic and morphosyntactic strategies, and thus qualifies as a mixed type (Type 3). In these languages, the distribution of plural agreement is largely lexically-specified: nouns denoting groups, masses, and collections are more likely to trigger plural agreement than other types of nouns. These results thus show that, similarly to the nominal domain, the lexical semantics of nouns may also affect plural marking on noun-associated forms. Furthermore, in Cushitic, radically morphosemantic and radically morphosyntactic number systems appear to be diachronically connected to each other, with the latter seemingly evolving from the former, as testified by ongoing variation and change in some of the sampled languages. The relevance of these findings for understanding the typology and evolution of number systems is discussed.
An Etiological Foxp2 Mutation Impairs Neuronal Gain in Layer VI Cortico-Thalamic Cells through Increased GABAB/GIRK Signaling
Authors: Druart Mélanie , Groszer Matthias , Le Magueresse Corentin 
Published: October 2020

A rare mutation affecting the Forkhead-box protein P2 (FOXP2) transcription factor causes a severe monogenic speech and language disorder. Mice carrying an identical point mutation to that observed in affected patients (Foxp2+/R552Hmice) display motor deficits and impaired synaptic plasticity in the striatum. However, the consequences of the mutation on neuronal function, in particular in the cerebral cortex, remain little studied. Foxp2 is expressed in a subset of Layer VI cortical neurons. Here, we used Ntsr1-EGFP mice to identify Foxp2+ neurons in the mouse auditory cortexex vivo.We studied the functional impact of the R552H mutation on the morphologic and functional properties of Layer VI cortical neurons from Ntsr1-EGFP; Foxp2+/R552Hmale and female mice. The complexity of apical, but not basal dendrites was significantly lower in Foxp2+/R552Hcortico-thalamic neurons than in control Foxp2+/+neurons. Excitatory synaptic inputs, but not inhibitory synaptic inputs, were decreased in Foxp2+/R552Hmice. In response, homeostatic mechanisms would be expected to increase neuronal gain, i.e., the conversion of a synaptic input into a firing output. However, the intrinsic excitability of Foxp2+ cortical neurons was lower in Foxp2+/R552Hneurons. A-type and delayed-rectifier (DR) potassium currents, two putative transcriptional targets of Foxp2, were not affected by the mutation. In contrast, GABAB/GIRK signaling, another presumed target of Foxp2, was increased in mutant neurons. Blocking GIRK channels strongly attenuated the difference in intrinsic excitability between wild-type (WT) and Foxp2+/R552Hneurons. Our results reveal a novel role for Foxp2 in the control of neuronal input/output homeostasis.SIGNIFICANCE STATEMENTMutations of the Forkhead-box protein 2 (FOXP2) gene in humans are the first known monogenic cause of a speech and language disorder. The Foxp2 mutation may directly affect neuronal development and function in neocortex, where Foxp2 is expressed. Brain imaging studies in patients with a heterozygous mutation in FOXP2 showed abnormalities in cortical language-related regions relative to the unaffected members of the same family. However, the role of Foxp2 in neocortical neurons is poorly understood. Using mice with a Foxp2 mutation equivalent to that found in patients, we studied functional modifications in auditory cortex neuronsex vivo. We found that mutant neurons exhibit alterations of synaptic input and GABAB/GIRK signaling, reflecting a loss of neuronal homeostasis.
Comparative Brain Imaging Reveals Analogous and Divergent Patterns of Species and Face Sensitivity in Humans and Dogs
Authors: Bunford Nóra , Hernández-Pérez Raúl , Farkas Eszter Borbála , Cuaya Laura V. , Szabó Dóra , Szabó Ádám György , Gácsi Márta , Miklósi Ádám , Andics Attila 
Published: October 2020

Conspecific-preference in social perception is evident for multiple sensory modalities and in many species. There is also a dedicated neural network for face processing in primates. However, the evolutionary origin and the relative role of neural species sensitivity and face sensitivity in visuo-social processing are largely unknown. In this comparative study, species sensitivity and face sensitivity to identical visual stimuli (videos of human and dog faces and occiputs) were examined using functional magnetic resonance imaging in dogs (n= 20; 45% female) and humans (n= 30; 50% female). In dogs, the bilateral mid suprasylvian gyrus showed conspecific-preference, no regions exhibited face-preference, and the majority of the visually-responsive cortex showed greater conspecific-preference than face-preference. In humans, conspecific-preferring regions (the right amygdala/hippocampus and the posterior superior temporal sulcus) also showed face-preference, and much of the visually-responsive cortex showed greater face-preference than conspecific-preference. Multivariate pattern analyses (MVPAs) identified species-sensitive regions in both species, but face-sensitive regions only in humans. Across-species representational similarity analyses (RSAs) revealed stronger correspondence between dog and human response patterns for distinguishing conspecific from heterospecific faces than other contrasts. Results unveil functional analogies in dog and human visuo-social processing of conspecificity but suggest that cortical specialization for face perception may not be ubiquitous across mammals.SIGNIFICANCE STATEMENTTo explore the evolutionary origins of human face-preference and its relationship to conspecific-preference, we conducted the first comparative and noninvasive visual neuroimaging study of a non-primate and a primate species, dogs and humans. Conspecific-preferring brain regions were observed in both species, but face-preferring brain regions were observed only in humans. In dogs, an overwhelming majority of visually-responsive cortex exhibited greater conspecific-preference than face-preference, whereas in humans, much of the visually-responsive cortex showed greater face-preference than conspecific-preference. Together, these findings unveil functional analogies and differences in the organizing principles of visuo-social processing across two phylogenetically distant mammal species.
REVIEW ON POTENTIAL TARGETED THERAPY FOR TRIPLE NEGATIVE BREAST CANCER
Authors: Aminuddin Nurul Issttifa , Edros Raihana , Kutty Rajaletchumy Veloo 
Published: October 2020

Triple negative breast cancer (TNBC) is a very aggressive type of cancer. TNBC is not just a single type of disease to be cured, but it consists of 6 subtypes which are basal-like 1 and 2, immunomodulatory, mesenchymal, mesenchymal stem- like and luminar androgen receptor. These subtypes has diverse characteristics, which hold potential opportunity for targeted treatment. Lack of molecular targets for triple negative tumor lead to limited targeted therapies for TNBC. Therefore, effective targeted therapies are urgently needed for TNBC. This paper will highlight on the potential targets in TNBC and treatment options that are currently under clinical application.
El órgano de la Basílica de Chiquinquirá: 125 años. Pesquisas que reconstruyen su historia
Authors: Peña Aponte Julio César 
Published: October 2020

Este artículo presenta información recopilada de diferentes fuentes acerca del órgano tubular de la Basílica de Chiquinquirá. Señala datos que hasta hoy son desconocidos por la feligresía mariana, la comunidad de frailes dominicos y la ciudadanía en general de la Capital Religiosa de Colombia. A partir de fuentes bibliográficas, documentales y testimoniales, recoge una serie de datos acerca de la casa fabricante y del papel que jugaron algunas personas en la intermediación, adquisición, instalación e interpretación del instrumento durante sus primeras décadas (finales del siglo XIX y principios del siglo XX). El artículo se basa en información proveniente principalmente de trabajos investigativos en España y Colombia acerca de la organería española de la época y específicamente de los órganos de la casa Amezua enviados a Colombia, sobre los cuales aporta nuevos hallazgos.
El artículo contribuye a reconstruir la historia de uno de los primeros y más grandes órganos tubulares llegados al país a finales del siglo XIX. La indagación que sustenta el artículo permitió encontrar también datos que corroboran y complementan lo que se conoce sobre la llegada del órgano de la Catedral de Bogotá y el órgano de la Candelaria, construidos por la misma casa de organería Amezua. Presenta además algunos registros fotográficos únicos sobre algunas personas directamente relacionadas con la historia estos órganos. Una de estas fotografías podría constituirse en el registro visual más antiguo conocido del órgano Amezua de la Catedral de Bogotá (1891).
On the Loss of Final -m: Phonological or Morphosyntactic Change?*
Authors: Adamik Béla 
Published: October 2020

SummaryThis paper intends to show that when grouping the various kinds of omissions of final -m in Väänänen‘s study on the Vulgar Latin of Pompeian inscriptions, the subcategories in his category b) (‘m omis sans raison apparente’ i.e. where -m is omitted due to a phonetic process) as “Accusatifs en -a(m)” like Succesus amat ancilla(m) and ad porta(m) Romana(m) or “Accusatifs en -e(m)” such as qu(a)e amas Felicione(m) and ante aede(m) must be rearranged in the following two subcategories: 1) cases after prepositions like ad porta(m) Romana(m) and ante aede(m) etc. where besides the phonetic interpretation a parallel morphosyntactic explanation of case confusion cannot be ruled out; and 2) cases with the objective use connected to verbs like Succesus amat ancilla(m) and qu(a)e amas Felicione(m) where, due to the preference of the phonetic interpretation, the morphosyntactic explanation seems to be less probable or even unlikely.
Variation and Change in Latin Close Appositions
Authors: Gianollo Chiara , Magni Elisabetta 
Published: October 2020

Summary:Close appositions are binominal constructions in which the two nouns are combined and denote a single entity. Throughout the history of Latin, syntactic and morphological variation in appositions point to a gradient from juxtapositional structures, where the two members are semantically and syntacti- cally on a par, to hierarchical structures, where the two members build various semantic and syntactic relations, yielding multiple and context-dependent interpretations. As it will be shown, the gradient-based model proposed in this paper captures variation and change in close appositions more adequately than approaches attributing an invariant internal structure to these constructions.
How Do New Languages Arise? A Comparison of Romanization and Gallicization
Authors: Gulyás Adrienn 
Published: October 2020

SummaryThis paper compares the romanization of Gaul in the 1st century BC and the gallicization of the island of Martinique during 17th-century French colonial expansion, using criteria set out by Muf- wene's Founder Principle. The Founder Principle determines key ecological factors in the formation of creole vernaculars, such as the founding populations and their proportion to the whole, language varieties spoken, and the nature and evolution of the interactions of the founding populations (also referred to as “colonization styles”). Based on the comparison, it will be claimed that new languages arise when a language undergoes vehicularization and subsequently shifts from one speech community to another. In other words, linguistic genesis would be a complicated case of language contact, where not only one, but sev- eral dialects of both superstrate and substrate varieties are involved, in a historical context where the identity function of language, or the norm, is overriden by the need to communicate. Research also indicates that language varieties spoken at the time of the shift did not pertain to normative usage, but to popular varieties, dialects, or both, since the emerging vernaculars - in Gaul, as well as in Martinique - preserved some of their phonological and lexical particularities.
The Grammarian Consentius on Errors Concerning the Accent in Spoken Latin
Authors: Mari Tommaso 
Published: October 2020

Summary:The 5th-century Gaulish grammarian Consentius wrote an extensive treatise on errors in spoken Latin. In the Roman grammatical tradition, errors in single words are deemed to arise by means of the improper addition, removal, substitution, and misplacement of one of the constitutive elements of the word (letter, syllable, quantity, accent, and aspiration). Late grammarians assumed that the four catego- ries of change applied to accents too, but only Consentius provided an example for each of these cases. However, his discussion poses some problems. The examples of removal, substitution and misplacement of an accent all concern the word orator and present oddities such as a circumflex accent on the antepe- nultimate syllable; they were clearly made up for the sake of completeness and have no bearing on our understanding of Vulgar Latin. On the other hand, the example of addition of an accent is tríginta, with retraction of the accent on the antepenultimate syllable; this must be genuine and fits in well with current reconstructions of most Romance continuations of Latin triginta (Italian trenta, French trente, etc.) and other vigesimals (uiginti, quadraginta, etc.).
La química como auxilio ambiental de los ecosistemas y de las poblaciones en el Perú
Authors: DANIEL LOVERA  , LIA CONCEPCIÓN  , MIRIAM MEJIA  , NELLY AUCASSI  , VLADIMIR ARIAS  , EDWIN MANRIQUE  , ANSELMO SÁNCHEZ  , BLANCA PERALTA  
Published: October 2020

La minería informal aurífera a nivel nacional e internacional tiene una producción anual importante que muchas veces supera la producción formal, la tecnología de recuperación del oro que utilizan es la clásica Amalgamación con Mercurio:
MAu + Hg → Au-Hg + M
Au – Hg → Au + Hg ↑
Dado la Convención de MINAMATA en el cual se precisa los peligros del Mercurio para los ecosistemas y la salud de las poblaciones, es bueno optar por otras tecnologías diferentes a la convencional de Amalgamación - Cianuración ampliamente usadas en la minería informal y formal para procesar sus minerales y relaves. Elsner en 1846 identificó correctamente la reacción química que forma la base de todos los procesos de lixiviación de cianuro en el oro: 4 Au + 8 NaCN + O2 + 2 H2O → 4 Na[Au(CN)2] + 4 NaOH. En el marco de las tecnologías limpias, es preciso recurrir a procesos metalúrgicos alternativos para la recuperación aurífera como la concentración gravimétrica y la lixiviación por agitación utilizando Tiourea, Sandioss y Goldmax entre otros reactivos. Mostramos las reacciones del proceso de recuperación de Oro por Tiourea:
2 (CS (NH2)2)2+ ↔ NH2 (NH) CSSC (NH) NH2 + 2 H+ + 2 e-
2 Au+ + NH2 (NH) CSSC (NH) NH2 + 2 H+ + e- ↔ 2 Au (CS (NH2)2)2+
2 Au (CS (NH2)2)2+ + e- ↔ 2 Au0 + 2 (CS (NH2)2)2+
Mostramos resultados de modelamientos y simulaciones de datos experimentales en la obtención de Oro y Plata, considerando la necesidad de emplear procesos que no afecten el medio ambiente y la vida, donde procesar minerales con alto contenido de arsénico, antimonio y cobre que son cianicidas, así como su posterior remediación, resultan antieconómicos. Se realizaron pruebas a nivel laboratorio para obtener parámetros de trabajo con el objetivo de lograr porcentajes de recuperación óptima y el consumo moderado de reactivos. Las pruebas se realizaron por agitación usando carbón activado, los resultados se muestran en los gráficos al final del trabajo.
Microplásticos en contenido estomacal de la “lisa” Mugil cephalus, Lima -Perú
Authors: SANTOS JENNY GAVILÁN , CORREA YELITZA ORTIZ , BACA KENER ARANDA , FLORES-GÓMEZ STIVE 
Published: October 2020

Resumen
Los plásticos presentes en los ríos, lagos lagunas, mares y diferentes ecosistemas terrestres, constituyen un serio problema de contaminación y atentan contra la salud de las diferentes especies que habitan los ecosistemas mencionados. Como consecuencia de esta contaminación, en los mares, los peces confunden el plástico con su alimento y los consumen quedando contaminados, según lo indican varios estudios realizados en diferentes partes del mundo. La especie Mugil cephalus conocido en Perú como “lisa”, es ampliamente consumido en toda la costa del Perú y común en los mercados de Lima, dada a su importancia, se realizó este estudio que tuvo el objetivo de determinar la presencia de plástico en el contenido estomacal del recurso. Se analizó el contenido estomacal de tres peces adquiridos en el mercado de Villa María del Triunfo (Lima). Se realizó la identificación y cuantificación de los organismos biológicos consumidos por los peces, pero también se evaluó la presencia de plástico. Según los análisis realizados, efectivamente encontraron varios taxones de fitoplancton y zooplancton, común dieta de esta especie, pero también evidenciamos, luego de haber aplicado la prueba de flotabilidad con cloruro de calcio, la presencia de microplásticos en el estómago de peces. Es necesario que el estado tome acciones para dar solución a este problema de interés para la salud del mar y de los consumidores en el Perú.
Six Patients with MethylmalonicAcidemia and Their Outcome: A Literature Review and Case Series
Authors: Mirhosseini Naser  Ali , Taghiyar Sana , Saatchi Mahdieh 
Published: October 2020

Background: Methylmalonic acidemia (MMA) is a congenital disorder due to the defects in the propionate pathway. It results from a deficiency in methylmalonyl coenzyme A mutase or one of the steps of the synthesis of the cobalamin (B12) cofactors for the enzyme. There is deficiency of methylmalonylcoAmutase (MCM) in the classic MMA. It presents with severe metabolic acidosis in the first month of life, progressive failure to thrive, feeding problems, recurrent vomiting, dehydration, hepatomegaly, lethargy, seizures, and developmental delay. Quantitative analysis of urinary organic acid patterns by GC-MS is used in MMA diagnosis. Treatment with large doses of hydroxocobalamin is helpful in some cases of MMA.
Case presentation:We Reported 6 patients with MMA with a variety of clinical manifestations and outcomes.
Conclusion: The overall prognosis of classic MMA remains doubtful, whereas vitamin B12 responsive MMA has a reasonable outcome.
Gestion des Dechets Menagers dans les Communes dâ€™adjame et de Bingerville dans le District Autonome dâ€™Abidjan, Cote dâ€™Ivoire
Authors: Alexis Nâ€™tamon Ekissi 
Published: October 2020

Dans le district dâ€™Abidjan, la quantitÃ© de dÃ©chets mÃ©nagers a connu au cours des derniÃ¨res dÃ©cennies un accroissement rapide en raison de lâ€™urbanisation accÃ©lÃ©rÃ©e qui le caractÃ©rise. Dans ses diffÃ©rentes communes notamment celles dâ€™AdjamÃ© et de Bingerville, on constate la prÃ©sence dâ€™ordures mÃ©nagers dans les caniveaux, aux abords des routes et sur les voies publiques. Ce phÃ©nomÃ¨ne dÃ» Ã la mauvaise gestion des dÃ©chets mÃ©nagers, provoque des odeurs nausÃ©abondes et la prolifÃ©ration des risques sanitaires. La prÃ©sente Ã©tude a pour objectif dâ€™identifier les facteurs explicatifs de la persistance des pratiques Ã risques des mÃ©nages. Dans une perspective beaucoup plus qualitative, lâ€™Ã©tude documentaire, lâ€™observation directe et un questionnaire semi-ouvert ont Ã©tÃ© mobilisÃ©s pour obtenir les donnÃ©es. Lâ€™interprÃ©tation de nos rÃ©sultats a Ã©tÃ© basÃ©e sur la thÃ©orie structuralismeconstructiviste de Pierre Bourdieu et la thÃ©orie sociologique du risque dâ€™Ulrich Beck. De lâ€™analyse des rÃ©sultats obtenus, il ressort que les mÃ©nages utilisent les dÃ©chets comme matÃ©riel utile Ã leur environnement. Par ailleurs, ils estiment que les risques sanitaires liÃ©s Ã la gestion des dÃ©chets mÃ©nagers, sont non mortels et ont une perception socio-culturelle des maladies causÃ©es par cette derniÃ¨re.
In the district of Abidjan, the quantity of household waste has experienced a rapid increase in recent decades due to the accelerated urbanization that characterizes it. In its various municipalities, especially those of AdjamÃ© and Bingerville, there is the presence of household garbage in the gutters, along roads and on public roads. This phenomenon, due to the poor management of household waste, causes foul odors and the proliferation of health risks. The objective of this study is to identify the explanatory factors for the persistence of risky household practices. From a much more qualitative perspective, the documentary study, direct observation and a semi-open questionnaire were used to obtain the data. The interpretation of our results was based on the structuralism-constructivist theory of Pierre Bourdieu and the sociological theory of risk of Ulrich Beck. From the analysis of the results obtained, it emerges that households use waste as material useful for their environment. In addition, they believe that the health risks associated with the management of household waste are non-fatal and have a socio-cultural perception of the diseases caused by the latter.