bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Trapezium and Simpson’s rules extended to three dimensions, with an application
Authors: Belcher Paul 
Published: February 2025

When limnologists (scientists who study lakes) wish to find the volume of a lake they find depth contours, where the depth of the lake is the same at any two points on the given contour. Let A (x) be the area contained in the contour at depth x. The function A (x) is assumed to be strictly decreasing with A (D) = 0 where D is the maximum depth of the lake. The standard formula for the volume that they use is
$$V \approx \sum\limits_{k = 1}^n {\frac{{{A_{k - 1}} + {A_k} + \sqrt {{A_k}_{ - 1}{A_k}} }}{2}\Delta x,{\text{ where }}{A_k}{\text{ = }}} A\left( {\frac{{kD}}{n}} \right)$$
over n + 1 equally-spaced depth contours with
$\Delta x{\text{ = }}\frac{D}{n}{\text{.}}$
This approach is very well analysed in [1].
Reduced protein solubility – cause or consequence in amyloid disease?
Authors: Lindberg Max , Hu Jing , Sparr Emma , Linse Sara 
Published: February 2025

Abstract
In this perspective, we ask the question whether the apparently lower solubility of specific proteins in amyloid disease is a cause or consequence of the protein deposition seen in such diseases. We focus on Alzheimer’s disease and start by reviewing the experimental evidence of disease-associated reduction in the measured concentration of amyloid β peptide, Aβ42, in cerebrospinal fluid. We propose a series of possible physicochemical explanations for these observations. These include a reduced solubility, a reduced apparent solubility, as well as a long-lived metastable state manifested in healthy individuals as a free concentration of Aβ42 in the solution phase above the solubility limit. For each scenario, we discuss whether it is most likely a cause or a consequence of the observed protein deposition in the disease.
‘The first step towards racial equality’: The Kuroda-Araya engagement and the dream of a transnational non-white alliance
Authors: Costantino Federica 
Published: February 2025

Abstract
In 1934, the much-publicized engagement of Japanese noblewoman Kuroda Masako to Ethiopian nobleman Araya Abebe made headlines worldwide, epitomizing the transnational dream of a racially anti-hierarchical world. Starting from this unrealized wedding, this article showcases the voice of Kuroda Masako, a racially equal imperial feminist who tried to foster her vision of women participating in the empire-building process even in new settings like Ethiopia. By featuring her practices, we are able to understand why they resonated not only in the women’s press but also in a much larger intellectual scene that comprised Pan-Asian and Pan-African activists. Because of such significant resonance across various non-governmental actors worldwide, the Kuroda-Araya engagement became dangerous to state-endorsed agendas in many countries, which were unwilling to countenance an unprecedented alliance between Ethiopia, Japan, and the African American community at the expense of Western and white civilization discourse. As a result, the engagement created a rupture between popular sympathy and the state, eventually resulting in Japan’s official disengagement from Ethiopia well before the Second Italo-Ethiopian War.
The rise and fall of science diplomacy in the Arctic: The “INTERACT” experience
Authors: Johansson Margareta , Callaghan Terry V. 
Published: February 2025

Abstract
At a time of increasing environmental changes and geopolitical tensions, the need for collaboration in the Arctic is greater than ever. Top-down initiatives such as the Arctic Council have contributed to important increased collaboration and science diplomacy. Similarly, bottom-up initiatives have also played a major role in establishing diplomacy among researchers with spin-offs at government levels. We track the rise of science diplomacy achieved by INTERACT. In 2021, this was a network of 90 research stations in 18 countries (including all Arctic nations). It aims to improve the wellness of Indigenous Peoples, other Arctic residents and the global community by facilitating environmental monitoring and research. It supports scientists from around the world and facilitates environmental monitoring for more than 150 international/global networks. INTERACT contributed to science diplomacy until spring 2022 when the invasion of Ukraine by Russia completely changed its pan-Arctic networking over a couple of months. This decrease in INTERACT science diplomacy was due entirely to external constraints related to the current geopolitical circumstances and poses a new reality for INTERACT and its important contributions to environmental monitoring and research in a region where changes have global implications.
Exposure profiles of social-environmental neighborhood factors and persistent distressing psychotic-like experiences across four years among young adolescents in the US
Authors: Ku Benson S. , Yuan Qingyue E. , Christensen Grace , Dimitrov Lina V. , Risk Benjamin , Huels Anke 
Published: February 2025

Abstract

Background
Recent research has demonstrated that domains of social determinants of health (SDOH) (e.g. air pollution and social context) are associated with psychosis. However, SDOHs have often been studied in isolation. This study investigated distinct exposure profiles, estimated their associations with persistent distressing psychotic-like experiences (PLE), and evaluated whether involvement in physical activity partially explains this association.

Methods
Analyses included 8,145 young adolescents from the Adolescent Brain and Cognitive Development Study. Data from the baseline and three follow-ups were included. Area-level geocoded variables spanning various domains of SDOH, including socioeconomic status, education, crime, built environment, social context, and crime, were clustered using a self-organizing map method to identify exposure profiles. Generalized linear mixed modeling tested the association between exposure profiles and persistent distressing PLE and physical activities (i.e. team and individual sports), adjusting for individual-level covariates including age, sex, race/ethnicity, highest level of parent education, family-relatedness, and study sites.

Results
Five exposure profiles were identified. Compared to the reference Profile 1 (suburban affluent areas), Profile 3 (rural areas with low walkability and high ozone), and Profile 4 (urban areas with high SES deprivation, high crime, and high pollution) were associated with greater persistent distressing PLE. Team sports mediated 6.14% of the association for Profile 3.

Conclusions
This study found that neighborhoods characterized by rural areas with low walkability and urban areas with high socioeconomic deprivation, pollution concentrations, and crime were associated with persistent distressing PLE. Findings suggest that various social-environmental factors may differentially impact the development of psychosis.
Sounds of pleasure and challenge behind the Iron Curtain: on the rise of Bulgarian rock music
Authors: Levy Claire 
Published: February 2025

Abstract
This article focuses on the innovative developments of some emblematic rock bands in Bulgaria, observed during the late 1970s and 1980s in terms of their social, ideological and artistic maturity, as well as of their significant impact on local youth life-styles through the liberating experience of specific musical styles ranging from classic rock (Shturtsite) and progressive rock (FSB) to, say, new wave (Tangra) or punk (Rock Trio Milena). Why the 1980s? What were the dominant verbal and musical messages at that time? Did they stimulate and accommodate the democratic political changes in 1989? In trying to answer such questions, the article develops a thesis according to which the acculturation of transnational musical models as the ones in the field of rock music is not a form of any flat mimicry of modern trends; this process inevitably passes through the filter of specific local contexts and subjective experiences.
In search of the bourgeoisie: Bob Morris and the urban history of class
Authors: Gunn Simon 
Published: February 2025

Abstract
Bob (or R.J.) Morris was probably best known in academic circles for his histories of class and specifically the British middle class. This essay traces his thinking about class in nineteenth- and early twentieth-century Britain from an early study of class consciousness to his later attempts to rework ideas about social structure and culture in a post-Weberian direction. A feature of this intellectual trajectory was the increasing importance of the city and urban place in the account of class formation, most evident in his work on Leeds. In the process, Bob carved out a distinctive type of urban social history which has proved highly influential in historical studies of social structure not only in Britain but in Europe and beyond.
Noise, yelling and dialects: sonic territories in two Copenhagen marketplaces 1790–1940
Authors: Quist Pia , Thelle Mikkel 
Published: February 2025

Abstract
In this article, we present an exploration of the social meaning and functions of marketplace sounds – including language, yelling and hailing – in two adjacent, yet very different sites in Copenhagen, Gammel Strand and Højbro Plads. We argue that the marketplace soundscapes played central functions as means of constructing customer-oriented semiotic spaces while negotiating territories and branding and selling products. Language by way of dialectal speech, yelling, street cries, cursing and swearing was an integral part of such processes. The two sites, by virtue of their physical placement in close proximity to each other, reinforced the contrasts between them, hence, co-constructing contrasting sonic territories – a concept which we employ and develop as part of the analysis. Central to our argument is that a sensory approach, including the sound of language, to a semiotic description of the urban marketplace requires a historical contextualization of the marketplace and its functions in the urban space, as well as of the life and culture of the marketplace vendors themselves; that is, the case in point, the female vendors from Amager and Skovshoved.
Battery-free head orientation measurement using passive RFID tags
Authors: Jo Jeyeon , Park Heeju T. 
Published: February 2025

Abstract
Real-time measurement of head rotation, a primary human body movement, offers potential advantages in rehabilitating head or neck motor disorders, promoting seamless human–robot interaction, and tracking the lateral glance of children with autism spectrum disorder for effective intervention. However, existing options such as cameras capturing the entire face or skin-attached sensors have limitations concerning privacy, safety, and/or usability. This research introduces a novel method that employs a battery-free RFID tag-based wearable sensor for monitoring head orientation, as a substitute for the existing options like camera. By attaching a pair of passive RFID tags to the front of the head at a specific distance from each other, the signal strength of each tag within the pair differs based on the discrepancy in distance from the RFID reader caused by head rotation. Important parameters including distance between the tags, distance from the reader, and tag types, are investigated to suggest optimal sensor design. In tests involving random head rotations by 10 healthy adults, there was a significant correlation between the orientation of the head and gaze in the yaw direction and the differences in signal strength from the sensor pairs. The correlation coefficients (

$ {r}^2 $

) were satisfactory, at 0.88 for head and 0.83 for left eye pupil orientations. However, the sensor failed to estimate pitch rotations for head and gaze, due to the insufficient vertical spacing between the tags. No demographic factors appeared to influence the results.
Quantifying Impacts of Vegetation Greenness Change on Drought Over Global Vegetation Zones
Authors: Sun Shanlei , Bi Zaoying , Mu Mengyuan , Liu Yi , Zhang Yifang , Li Jinjian , Liu Yibo , Zhou Yang , Zhou Botao , Chen Haishan 
Published: February 2025

AbstractChanges in vegetation greenness have altered the regional terrestrial water cycle, yet their influence on drought remains unclear. To quantify the impact of vegetation greenness change on drought across global vegetation zones, this study conducted two simulations with and without linear trends in the Leaf Area Index (LAI), based on the Standardized Precipitation‐Evapotranspiration Index (SPEI) combined with the calibrated Shuttleworth‐Wallace potential evapotranspiration (PET) equation. Results revealed vegetation greening affected 71% of areas, and over 55% of areas experienced increases in PET, decreases in SPEI (indicating drying), and intensified drought conditions. The linear trends in LAI increased potential transpiration but decreased potential soil evaporation in most regions. The changes in drought are determined by the combined effects of these changes in potential transpiration and soil evaporation. This study highlights the critical role of vegetation greenness change in influencing drought.
Orography‐Induced Atmospheric Small‐Scale Waves During Bora Using Lidar Observations and Numerical Simulations
Authors: Wang Longlong , Mačak Marija Bervida , Stanič Samo , Patruno Luca , Dong Wenjun , Chen Daru 
Published: February 2025

AbstractAtmospheric flow of cold air over mountain barriers in the Alpine region often gives a rise to strong and gusty downslope wind, Bora. Such flows are often accompanied by atmospheric waves, generated by the flow passing an elevated barrier. Such phenomenon can only rarely be observed visually and can generally not be reliably reproduced by simplified numerical models. Orography‐induced atmospheric small‐scale waves were experimentally observed on 25 January 2019 during a Bora outbreak in the Vipava valley, Slovenia. A vertical scanning lidar, positioned at the lee side of the Trnovski gozd mountain and a fixed direction lidar, 5 km apart in the Vipava valley, were used to characterize the density field. The flow exhibited a stationary jump after the mountain ridge and, superimposed, an oscillatory flow pattern. High‐resolution numerical simulations complemented the observations and supported experimental results on the flow periodicity but also on the wave structures and propagation characteristics.
SpiDa-MRI: behavioral and (f)MRI data of adults with fear of spiders
Authors: Zhang Mengfan , Karner Alexander , Kostorz Kathrin , Shea Sophia , Steyrl David , Melinscak Filip , Sladky Ronald , Lor Cindy Sumaly , Scharnowski Frank 
Published: February 2025

Abstract
Neuroimaging has greatly improved our understanding of phobic mechanisms. To expand on these advancements, we present data on the heterogeneity of neural patterns in spider phobia combined with various psychological dimensions of spider phobia, using spider-relevant stimuli of various intensities. Specifically, we have created a database in which 49 spider-fearful individuals viewed 225 spider-relevant images in the fMRI scanner and performed behavioral avoidance tasks before and after the fMRI scan. For each participant, the database consists of the neuroimaging part, which includes an anatomical scan, five passive-viewing, and two resting-state functional runs in both raw and pre-processed form along with associated quality control reports. Additionally, the behavioral section includes self-report questionnaires and avoidance tasks collected in pre- and post-sessions. The dataset is well suited for investigating neural mechanisms of phobias, brain-behavior correlations, and also contributes to the existing phobic neuroimaging datasets with spider-fearful samples.
α-spinasterol isolated from Achyranthes aspera L. ameliorates inflammation via NF-κB and Nrf2/HO-1 pathways
Authors: Zeng Qiongli , Xiao Weiting , Zhang Heng , Liu Wei , Wang Xionglong , Li Zhen , Han Yue , Wang Zhi , Li Shunxiang , Yang Jinwei , Ouyang Wen 
Published: February 2025

Abstract
On the basis of previous studies, the low-polar part of Achyranthes aspera L. (A. aspera) had strong anti-inflammatory activity. Three compounds were isolated from the low polarity fraction of A. aspera, and their structures were identified as α-spinasterol (1), 7,8-dihydrospinasterol (2), 22,23-dihydrospinasterol (3). Among them, the content of α-spinasterol (1) in A. aspera was higher in the spring and winter seasons through HPLC methods, ranging from 0.0085 to 0.0157%. Futhermore, in the LPS-induced RAW264.7 cells inflammation model, α-spinasterol significantly reduced the levels of cytokines such as IL-6, PGE2 and TNF-α, inhibited the expression of COX-2, 5-LOX, p-IKKβ, p-NFκB and p-IkBα proteins, and promoted the expression of Nrf2, HO-1 and NQO1 proteins. Therefore, this study showed that α-spinasterol can inhibit LPS-induced RAW264.7 cells inflammation, and its mechanism may be related to the inhibition of NF-κB pathway, activation of Nrf2 pathway, and reduction of excessive release of inflammatory factors.
Seagrass-rafted large benthic foraminifera transported into the deep Red Sea
Authors: Stuhr Marleen , Westphal Hildegard , Marchese Fabio , Mateu-Vicens Guillem , Giovenzana Francesca , Lüdmann Thomas , Vahrenkamp Volker , Taviani Marco 
Published: February 2025

Abstract
Large shallow-marine foraminifera tests occur in deep-sea carbonate sediments of the northern Red Sea as a minor but recurring component among the remains of otherwise pelagic and deep-marine benthic biogenic assemblages. In this study of sediments recovered along the northern shore of Saudi Arabia, the symbiont-bearing taxa Sorites variabilis, S. orbiculus, Amphisorus hemprichii, Amphistegina lobifera, A. lessonii and A. radiata were identified in samples from between 430 to 1,000 m depth. These foraminifera are dwelling in shallow-water environments, associated with coral reefs and seagrass habitats. The seemingly erratic occurrence of photosymbiotic benthic organisms in deep-sea sediments was explained by the finding of such foraminifera tests along with seagrass (e.g., Halophila leaves) and macroalgae remains in pristine preservational states in the sediment of the Umluj brine pool below ~ 638 m depth. This indicates a passive transport process by rafting attached to floating macrophytes to these off-platform settings. The abundant seagrass and oceanographic conditions along the Arabian Peninsula may facilitate the transport of epiphytes and associated taxa offshore. Such long-distance transport mechanisms could further contribute to the rapid (co-)dispersal of some of these organisms into new habitats. Passive rafting should thus be considered in interpretation of sedimentary records and biogeographic patterns.
Enhanced flux potential analysis links changes in enzyme expression to metabolic flux
Authors: Li Xuhang , Walhout Albertha J M , Yilmaz L Safak 
Published: February 2025

Abstract
Algorithms that constrain metabolic network models with enzyme levels to predict metabolic activity assume that changes in enzyme levels are indicative of flux variations. However, metabolic flux can also be regulated by other mechanisms such as allostery and mass action. To systematically explore the relationship between fluctuations in enzyme expression and flux, we combine available yeast proteomic and fluxomic data to reveal that flux changes can be best predicted from changes in enzyme levels of pathways, rather than the whole network or only cognate reactions. We implement this principle in an ‘enhanced flux potential analysis’ (eFPA) algorithm that integrates enzyme expression data with metabolic network architecture to predict relative flux levels of reactions including those regulated by other mechanisms. Applied to human data, eFPA consistently predicts tissue metabolic function using either proteomic or transcriptomic data. Additionally, eFPA efficiently handles data sparsity and noisiness, generating robust flux predictions with single-cell gene expression data. Our approach outperforms alternatives by striking an optimal balance, evaluating enzyme expression at pathway level, rather than either single-reaction or whole-network levels.
Repression of apelin Furin cleavage sites provides antimetastatic strategy in colorectal cancer
Authors: Demoures Béatrice , Soulet Fabienne , Descarpentrie Jean , Galeano-Otero Isabel , Sanchez Collado José , Casado Maria , Smani Tarik , González Alvaro , Alves Isabel , Lalloué Fabrice , Masri Bernard , Rascol Estelle , Dupuy Jean-William , Dourthe Cyril , Saltel Frédéric , Raymond Anne-Aurélie , Badiola Iker , Evrard Serge , Villoutreix Bruno , Pernot Simon , Siegfried Géraldine , Khatib Abdel-Majid 
Published: February 2025

Abstract
The adipokine apelin has been directly implicated in various physiological processes during embryogenesis and human cancers. Nevertheless, the importance of the conversion of its precursor proapelin to mature apelin in tumorigenesis remains unknown. In this study, we identify Furin as the cellular proprotein convertase responsible for proapelin cleavage. We explore the therapeutic potential of targeting proapelin cleavage sites in metastatic colorectal cancer by introducing apelin-dm, a modified variant resulting from alteration in proapelin cleavage sites. Apelin-dm demonstrates efficacy in inhibiting tumor growth, promoting cell death, suppressing angiogenesis, and early colorectal liver metastasis events. Proteomic analysis reveals reciprocal regulation between apelin and apelin-dm on proteins associated with clinical outcomes in colon cancer patients. Apelin-dm emerges as a modulator of apelin receptor dynamics, influencing affinity, internalization, and repression of apelin signaling linked to various protein kinases. Pharmacokinetic and toxicity assessments confirm the specificity, safety, and stability of apelin-dm, as well as its facile hepatic metabolism. These findings position targeting proapelin cleavage as a promising therapeutic strategy against metastatic colorectal cancer, paving the way for further clinical exploration.
Unlocking high capacitive energy-density in Sm-doped Pb(Mg1/3Nb2/3)O3–PbTiO3 thin films via strain and domain engineering
Authors: Hanani Zouhair , Belhadi Jamal , Daneu Nina , Trstenjak Urška , Shepelin Nick A. , Bobnar Vid , Lippert Thomas , Spreitzer Matjaž 
Published: February 2025

Sm-doped Pb(Mg1/3Nb2/3)O3–30PbTiO3 relaxor ferroelectric thin films with slush-like structure demonstrate ultra-high energy density, excellent thermal stability and fatigue-free energy storage properties.
CSS‐UNet: Convolution‐State Space Enhanced UNet for Cardiac MRI Segmentation
Authors: Tong Yaliang , Liu Kun , He Yuquan , Yang Ping 
Published: February 2025

AbstractCardiac magnetic resonance imaging (CMR) is widely adopted in clinic for the assessment of cardiac anatomical structures and functions, and accurately segmenting left ventricular, myocardium and right ventricle from CMR plays an important role in clinical practice. Convolutional neural networks (CNNs), for example, U‐Net, have been widely used in CMR segmentation. However, current CNN‐based models focus on extracting local features via convolution modules, which cannot well understand the long‐range dependencies within images, leading to the sub‐optimal solution for CMR segmentation task. Inspired by Mamba that efficiently captures global context information using state space model, we propose a novel CMR segmentation model, called CSS‐UNet, that can capture both local features and global contexts simultaneously by fusing features from convolution block and visual state space block. Our new model follows the design of U‐Net architecture that contains encoder and decoder with skip connections, where a proposed feature fusion module, called spatial‐state space, is seamlessly integrated into our model. By using the spatial‐state space module, the low‐level and high‐level features can be extracted and fused for capturing both global and local information, enhancing the capability of feature extraction of CSS‐UNet. We evaluate our proposed model on two public CMR datasets, and the experimental results reveal that our proposed model outperforms the most widely‐used UNet, demonstrating the effectiveness of our model.