bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of two-point models in “Model choice in time-series studies of air pollution and mortality”
Authors: Szyszkowicz Mieczysław 
Published: January 2020

AbstractIn this work, a new technique is proposed to study short-term exposure and adverse health effects. The presented approach uses hierarchical clusters with the following structure: each pair of two sequential days in 1 year is embedded in the year. We have 183 clusters per year with the embedded structure <year:2 days>. Time-series analysis is conducted using a conditional Poisson regression with the constructed clusters as a stratum. Unmeasured confounders such as seasonal and long-term trends are not modelled but are controlled by the structure of the clusters. The proposed technique is illustrated using four freely accessible databases, which contain complex simulated data. These data are available as the compressed R workspace files. Results based on the simulated data were very close to the truth based on the presented methodology. In addition, the case-crossover method with 1-month and 2-week window, and a conditional Poisson regression on 3-day clusters as a stratum, was also applied to the simulated data. Difficulties (high type I error rate) were observed for the case-crossover method in the presence of high concurvity in the simulated data. The proposed methods using various forms of a stratum were further applied to the Chicago mortality data. The considered methods have often different qualitative and quantitative estimations.
The Intergenerational Effects of Intermarriage
Authors: Tegunimataka Anna 
Published: January 2020

AbstractThis study closely examines long-term outcomes of intermarriage in Denmark in terms of children’s educational performance, studying grades from final examinations. The study uses rich register data, where families are linked across generations, and contributes to the migration literature by providing new insights into the human capital formation in inter-ethnic families. The outcomes of children of intermarriage are very much in line with the outcomes of children with two native-born Danish parents. Compared to second-generation immigrants, children of intermarriage perform substantially better, and these differences remain even when school and family-level confounders are taken into account. Moreover, this paper explores the heterogeneous character of the 2.5 generation in Denmark and studies the importance of parental country of origin. Parental country of origin is of significance for the educational performance of children from intermarriage in Denmark, as the performance of children with a non-native parent originating from countries of Africa, Asia, and Latin America is closer to that of second-generation immigrants, rather than natives. This association remains (for certain groups) when controlling for unobserved heterogeneity at the school and family level.
Standard friction prediction model of long-distance hot oil pipelines
Authors: Yu Tao , Li Chuan-xian , Yao Bo , Zhang Zhi-jun , Guo Yi , Liu Li-jun 
Published: January 2020

AbstractWe developed a predictive model for the pipeline friction in the 520–730 m3/h transmission range using the multi-layer-perceptron–back-propagation (MLP–BP) method and analyzing the unit friction data after the pigging of a hot oil pipeline. In view of the shortcomings of the MLP–BP model, two optimization methods, the genetic algorithm (GA) and mind evolutionary algorithm (MEA), were used to optimize the MLP–BP model. The research results were applied to the standard friction prediction of three sections of a hot oil pipeline. After the GA and MEA optimizations, the average errors of the three sections were 0.0041 MPa for the GA and 0.0012 MPa for the MEA, and the mean-square errors were 0.083 and 0.067, respectively. The MEA-BP model prediction results were characterized by high precision and small dispersion. The MEA-BP prediction model was applied to the analysis of the wax formation 60 and 90 days after pigging. The analysis results showed that the model can effectively guide pipe pigging and optimization. There was little sample data for the individual transmission and oil temperature steps because the model was based on actual production data modeling and analysis, which may have affected the accuracy and adaptability of the model.
The Japanese Breast Cancer Society clinical practice guidelines for surgical treatment of breast cancer, 2018 edition
Authors: Inokuchi Masafumi , Kutomi Goro , Kijima Yuko , Sakai Takehiko , Sawaki Masataka , Shien Tadahiko , Hanamura Noriko , Yano Kenji , Wada Noriaki , Saji Shigehira , Iwata Hiroji 
Published: January 2020

AbstractWe have prepared the Japanese Breast Cancer Society clinical practice guidelines (CPGs) for surgical treatment of breast cancer, 2018 update after a systematic review (SR) of the literature based upon the Medical Information Network Distribution Service (Minds) procedure. The CPG committee for surgical treatment of breast cancer, composed of breast surgeons and plastic surgeons treating breast cancer, has developed the CPGs. Eight clinical questions (CQs) were selected and divided roughly into the following five categories: (1) breast surgery in initial therapy (CQs 1–3); (2) axillary surgery in initial therapy (CQs 4–5); (3) breast reconstruction in initial therapy (CQ 6); (4) surgical treatment for recurrent and metastatic breast cancer (CQs 7–8); and (5) others. Recommendations for these CQs were decided by the GRADE grid method. In addition, 4 outlines, 14 background questions (BQs), and 12 future research questions (FQs) were also selected. Statements for these BQs and FQs are provided. We developed the updated CPGs for surgical treatment of breast cancer, 2018, which include 8 CQs and recommendations. As a decision-making tool for the understanding and treatment of breast cancer, these guidelines will help surgical oncologists dealing with breast cancer, medical staff, and patients, along with their family members.
miR-362-5p promotes cell proliferation and cell cycle progression by targeting GAS7 in acute myeloid leukemia
Authors: Wu Fuqun , Yin Changxin , Qi Junhua , Duan Deyu , Jiang Xi , Yu Jianhua , Luo Zhaofan 
Published: January 2020

AbstractRecently, miR-362-5p has attracted special interest as a novel prognostic predictor in acute myeloid leukemia (AML). However, its biological function and underlying molecular mechanism in AML remain to be further defined. Herein, we found that a significant increase in miR-362-5p expression was observed in AML patients and cell lines using quantitative real-time PCR. The expression of miR-362-5p was altered in THP-1 and HL-60 cells by transfecting with miR-362-5p mimic or inhibitor. A series of experiments showed that inhibition of miR-362-5p expression significantly suppressed cell proliferation, induced G0/G1 phase arrest and attenuated tumor growth in vivo. On the contrary, ectopic expression of miR-362-5p resulted in enhanced cell proliferation, cell cycle progression and tumor growth. Moreover, growth arrest-specific 7 (GAS7) was confirmed as a direct target gene of miR-362-5p and was negatively modulated by miR-362-5p. GAS7 overexpression imitated the tumor suppressive effect of silenced miR-362-5p on THP-1 cells. Furthermore, miR-362-5p knockdown or GAS7 overexpression obviously down-regulated the expression levels of PCNA, CDK4 and cyclin D1, but up-regulated p21 expression. Collectively, our findings demonstrate that miR-362-5p exerts oncogenic effects in AML by directly targeting GAS7, which might provide a promising therapeutic target for AML.
A physically consistent particle method for incompressible fluid flow calculation
Authors: Kondo Masahiro 
Published: January 2020

AbstractIn general, mechanical energy monotonically decreases in a physically consistent system, constructed with conservative force and dissipative force. This feature is important in designing a particle method, which is a discrete system approximating continuum fluid with particles. When the discretized system can be fit into a framework of analytical mechanics, it will be a physically consistent system which prevents instability like particle scattering along with unphysical mechanical energy increase. This is the case also in incompressible particle methods. However, most incompressible particle methods do not satisfy the physical consistency, and they need empirical relaxations to suppress the system instability due to the unphysical energy behavior. In this study, a new incompressible particle method with the physical consistency, moving particle full-implicit (MPFI) method, is developed, where the discretized interaction forces are related to an analytical mechanical framework for the systems with dissipation. Moreover, a new pressure evaluation technique based on the virial theorem is proposed for the system. Using the MPFI method, static pressure, droplet extension, standing wave and dam break calculations were conducted. The capability to predict pressure and motion of incompressible free surface flow was presented, and energy dissipation property depending on the particle size and time step width was studied through the calculations.
Assessing the Function of Palaeolithic Hearths: Experiments on Intensity of Luminosity and Radiative Heat Outputs from Different Fuel Sources
Authors: Hoare Sally 
Published: January 2020

AbstractAssessing the function of Palaeolithic hearths is a key research issue that can benefit from the application of experimental archaeology when examining whether the behaviourally related purposes of fire, e.g. heat, light and cooking, could be correlated with combustion features in the archaeological record. Not all species of wood and types of fuel burn the same way. Variability exists in the amount of ash and smoke produced, along with differences in speed of burning and outgoing light and heat. This paper examined the light and heat properties of nine different types of fuels (eight individual species of wood and fresh bone) by assessing intensity of luminosity and radiative heat outputs using a lux metre and thermal imaging camera. Results show that there is considerable variation between bone and wood in terms of light and heat output and between the individual species of wood. In order to assess whether heat efficiency may vary seasonally, experiments were performed overnight and repeated at ambient air temperature ranges of 11 to 13 and 0 to 3 °C. Results show that in the current data set fuels that emit lower to intermediate heat outputs could be more efficient at colder temperatures in terms of warmth. This represents a preliminary step forward towards attributing behaviourally relevant functions such as light and heat to Palaeolithic combustion features with regard to fuel selectivity.
Understanding Race: The Case for Political Constructionism in Public Discourse
Authors: Ludwig David 
Published: January 2020

AbstractThe aim of this article is to develop an understanding-based argument for an explicitly political specification of the concept of race. It is argued that a specification of race in terms of hierarchical social positions is best equipped to guide causal reasoning about racial inequality in the public sphere. Furthermore, the article provides evidence that biological and cultural specifications of race mislead public reasoning by encouraging confusions between correlates and causes of racial inequality. The article concludes with a more general case for incorporating empirical evidence about public reasoning into philosophical debates about competing specifications of the concept of race.
Characteristics of Young-Onset and Late-Onset Dementia Patients at a Remote Memory Clinic
Authors: Wong Jennifer F. W. , Kirk Andrew , Perlett Landon , Karunanayake Chandima , Morgan Debra , O’Connell Megan E. 
Published: January 2020

ABSTRACT:Background:Young-onset dementia (YOD) is defined as the onset of dementia symptoms before the age of 65 years and accounts for 2–8% of dementia. YOD patients and their caregivers face unique challenges in diagnosis and management. We aimed to compare the characteristics of rural YOD and late-onset dementia (LOD) patients at a rural and remote memory clinic in Western Canada.Methods:A total of 333 consecutive patients (YOD = 61, LOD = 272) at a rural and remote memory clinic between March 2004 and July 2016 were included in this study. Each patient had neuropsychological assessment. Health, mood, function, behaviour and social factors were also measured. Both groups were compared using χ2 tests and independent sample tests.Results:YOD patients were more likely to be married, employed, current smokers and highly educated. They reported fewer cognitive symptoms, but had more depressive symptoms. YOD patients were less likely to live alone and use homecare services. YOD caregivers were also more likely to be a spouse and had higher levels of distress than LOD caregivers. Both YOD and LOD patient groups were equally likely to have a driver’s licence.Conclusions:Our findings indicate YOD and LOD patients have distinct characteristics and services must be modified to better meet YOD patient needs. In particular, the use of homecare services and caregiver support may alleviate the higher levels of distress found in YOD patients and their caregivers. Additional research should be directed to addressing YOD patient depression, caregiver distress and barriers to services.
Sobolev regularity of solutions of the cohomological equation
Authors: FORNI GIOVANNI 
Published: January 2020

In this survey we prove the sharpest results on the loss of Sobolev regularity for solutions of the cohomological equation for translation flows on translation surfaces, available to the methods developed by the author in Forni [Solutions of the cohomological equation for area-preserving flows on compact surfaces of higher genus. Ann. of Math. (2)146(2) (1997), 295–344] and Forni [Deviation of ergodic averages for area-preserving flows on surfaces of higher genus. Ann. of Math. (2)155(1) (2002), 1–103]. The paper was mostly written between 2005 and 2006 while the author was at the University of Toronto, Canada, and was posted on arXiv in July 2007 [Forni. Sobolev regularity of solutions of the cohomological equation. Preprint, 2007, arXiv:0707.0940v2]. In an updated introduction we describe our results, taking into account later work on the problem and relevant recent progress in the field of Teichmüller dynamics, interval exchange transformations and translation flows.
Sanctuary, Armory, and Prison: Switzerland and the Role of Swiss Anarchists as Intermediaries in the European Terrorist Network in the 1970s
Authors: Pešta Mikuláš 
Published: January 2020

AbstractThis article focuses on how Switzerland played a dual role in providing a sanctuary for retired left-wing radicals while serving as an armament source for the distribution of weapons and explosives throughout Europe in the 1970s. A significant part of the article delves into the case of the AKO (Anarchistische Kampforganisation), a Swiss anarchist group that supplied several European terrorist groups with weapons. The position of this group will be analyzed in the context of the transnational terrorist network as a way of assessing to what extent their cooperation with other groups was rooted in mutual ideological affiliations, and how closely the anarchist tradition, of which they were a part, related to the European framework of the New Left. The case of Petra Krause, one of the group's key figures, is latterly discussed, particularly her imprisonment in Switzerland and the campaign for her release, which mobilized a large number of supporters across Europe and contributed to the portrayal of Switzerland as a prison.
Rising CO2 in the field does not offset warming or drought constraints on leaf growth of a C3 forage
Authors: de Camargo-Bortolin L. H. G. , Habermann E. , Vicente P. , Barboza A. , Groppo M. , Prado C. H. B. A. , Martinez C. A. 
Published: January 2020

AbstractThe regrowth of a C3 forage Stylosanthes capitata in a rain-fed field provided the weekly data collection in the southeast of Brazil during a heat event in autumn. A system named Trop-T-FACE simulated the free-air carbon dioxide enrichment and the enhanced temperature in four climatic regimes: current atmospheric conditions (Control), CO2 enrichment (600 ppm, eC), warming (2 °C above ambient canopy temperature, eT), and a combination of eC + eT. The area and biomass of foliage per shoot decreased, and the number of flowers per shoot and flowered ramification increased under single eC treatment besides the increment in palisade parenchyma of leaves. Increased investment in flowering in eC occurred notably when the soil water content was higher than 0.30 m3 m–3. Single eT treatment also impaired the area or biomass of foliage production per shoot, raised the shoot mortality, and promoted the increment of the spongy leaf parenchyma. There was some mitigation of the adverse effects of foliage production of eT or eC in eC + eT, but under this combined treatment, the shoot mortality also increased. Changes in leaf tissues under eC or eT or some mitigation of adverse effects in eC + eT did not offset the constraints on leaf growth per shoot. The harmful impact on foliage production by eC, eT, or eC + eT under rain-fed conditions indicated no advantages for feeding the livestock with the C3 forage S. capitata in expected climate change under field conditions.
Incision of Hasner's valve under endoscopic intranasal surgery for the treatment of nasolacrimal duct obstruction in children
Authors: Keilani C , Keller P , Piaton J-M 
Published: January 2020

AbstractObjectiveTo evaluate the effectiveness and safety of a Hasner's valve incision performed under endoscopic intranasal surgery for the management of congenital nasolacrimal duct obstruction.MethodsThis retrospective study comprised 484 patients with congenital nasolacrimal duct obstruction who underwent incision of Hasner's valve under endoscopic intranasal surgery between April 2000 and October 2016. The primary endpoint was the procedure's functional success rate. The secondary endpoints were Hasner's valve and inferior turbinate anatomical findings, demographic data, complication rate and surgical duration.ResultsIn patients with no medical history of nasolacrimal duct probing, 91 per cent had a successful result, 5 per cent had a partially successful result, 3.9 per cent showed no change and 0.1 per cent had a worse result following the procedure. Concerning the secondary endpoints, outcomes were more frequently successful in children younger than three years. Only one patient had a post-operative infection. All patients underwent general anaesthesia; no complications related to general anaesthesia were observed. Mean surgical duration was 13.1 ± 5.7 minutes.ConclusionIncising Hasner's valve after medially displacing the inferior turbinate under nasal endoscopy seems to be an adequate primary surgical treatment for congenital nasolacrimal duct obstruction.
INCIDENTAL VOCABULARY LEARNING THROUGH VIEWING VIDEO
Authors: Montero Perez Maribel 
Published: January 2020

AbstractThere is growing evidence that L2 learners pick up new words while viewing video but little is known about the role of individual differences. This study explores incidental learning after viewing a French documentary containing 15 pseudowords and investigates whether learning is moderated by participants’ prior vocabulary knowledge and working memory. Sixty-three higher-intermediate learners of French participated in this study. Prior vocabulary knowledge was measured by means of a French meaning recognition test. Participants also took a forward digit-span (phonological short-term memory), a backward digit-span, and an operation-span task (complex working memory). After viewing the video, four surprise vocabulary tests on form and meaning were administered. Results revealed that learning gains occurred at the level of form and meaning recognition. Vocabulary knowledge was positively related to picking up new words from video. Complex working memory correlated with the recognition tests showing more incidental learning gains for learners with higher complex working memory.
Transplantation-free survival after Norwood surgery for hypoplastic left heart syndrome with aortic atresia: A Swedish national cohort study
Authors: Öhman Annika , El-Segaier Milad , Bergman Gunnar , Hanseus Katarina , Malm Torsten , Nilsson Boris , Pivodic Aldina , Rydberg Annika , Sonesson Sven-Erik , Mellander Mats 
Published: January 2020

AbstractBackground:Norwood surgery has been available in Sweden since 1993. In this national cohort study, we analysed transplantation-free survival after Norwood surgery for hypoplastic left heart syndrome with aortic atresia.Methods:Patients were identified from the complete national cohort of live-born with hypoplastic left heart syndrome/aortic atresia 1993–2010. Analysis of survival after surgery was performed using Cox proportional hazards models for the total cohort and for birth period and gender separately. Thirty-day mortality and inter-stage mortality were analysed. Patients were followed until September 2016.Results:The 1993–2010 cohort consisted of 208 live-born infants. Norwood surgery was performed in 121/208 (58%). The overall transplantation-free survival was 61/121 (50%). The survival was higher in the late period (10-year survival 63%) than in the early period (10-year survival 40%) (p = 0.010) and lower for female (10-year survival 34%) than for male patients (10-year survival 59%) (p = 0.002). Inter-stage mortality between stages I and II decreased from 23 to 8% (p = 0.008). For male patients, low birthweight in relation to gestational age was a factor associated with poor outcome.Conclusion:The survival after Norwood surgery for hypoplastic left heart syndrome/aortic atresia improved by era of surgery, mainly explained by improved survival between stages I and II. Female gender was a significant risk factor for death or transplantation. For male patients, there was an increased risk of death when birthweight was lower than expected in relation to gestational age.
Images of a large fistulous communication between the right ventricle and left anterior descending coronary artery
Authors: Alp Hayrullah , Elmacı Ahmet M. , Taşar Mehmet 
Published: January 2020

AbstractCoronary artery fistulas are relatively rare congenital or iatrogenic heart defects that can present with or without symptoms. Symptomatic patients manifest as myocardial ischaemia, arrhythmia, or heart failure. We present a asymptomatic child with a large left anterior descending coronary artery to right ventricular fistula.
Intake of trans-fats among US youth declined from 1999–2000 to 2009–2010
Authors: Restrepo Brandon J 
Published: January 2020

AbstractObjective:To analyse how much the intake of trans-fatty acids (TFA), an important dietary risk factor for CVD, changed among US children and adolescents over a period of time when food regulations that reduced the presence of TFA in the food supply were enacted.Design:Regression models were used to estimate changes in levels of TFA in plasma and other CVD risk factors among US children and adolescents from 1999–2000 to 2009–2010.Setting:USA.Participants:Nationally representative sample of children (aged 6–11 years) and adolescents (aged 12–19 years) who participated in the 1999–2000 and 2009–2010 cycles of the National Health and Nutrition Examination Survey.Results:Levels of plasma TFA declined significantly by an average of 61·9 % from 1999–2000 to 2009–2010. The average decline in a TFA commonly found in partially hydrogenated oils (elaidic acid, 67·2 %) was larger than the average decline in a TFA naturally occurring in ruminant animals (vaccenic acid, 60·5 %). Significant improvements in a variety of other CVD risk factors (LDL- and HDL-cholesterol, TAG, systolic and diastolic blood pressure, C-reactive protein) were also observed.Conclusions:Between the two time points, 1999–2000 and 2009–2010, there were substantial decreases in plasma TFA levels and improvements in several other important CVD risk factors in the population of US children and adolescents.