bluuebunny/crossref_metadata_2025_split huggingface dataset:
Xerogenic Medications as a Predictor for Dental Health Intervention in People with Dementia
Authors: Tan Edwin C.K. , Lexomboon Duangjai , Häbel Henrike , Fastbom Johan , Eriksdotter Maria , Johnell Kristina , Sandborgh-Englund Gunilla 
Published: May 2020

Background: Older adults with dementia often have poor oral health. Chronic use of xerogenic medications may contribute to adverse dental outcomes. Objective: To investigate the impact of xerogenic medication classes on the predicted risk for dental interventions in people with dementia. Methods: This was a population-based cohort study involving 30,955 individuals registered in the Swedish Dementia Registry (SveDem) from 2008 to 2015. Data were linked with other national registers. The exposure was xerogenic medication classes used in the three years prior to dementia diagnosis (baseline). The primary outcome was the composite of number of tooth extractions and dental restorations over the three-year follow-up period. Secondary outcomes included the number of tooth extractions and number of dental restorations. Poisson regression models were used to estimate the association between the exposure and outcomes. Analyses were adjusted for age, gender, Mini-Mental State Examination, living arrangement, dementia disorder, average number of medications, Charlson’s comorbidity index, number of dental visits, and number of teeth. Results: After adjusting for potential covariates, the use of urological drugs (incidence rate ratio [IRR] 1.16, 95% CI 1.04–1.28), proton pump inhibitors (IRR 1.13, 95% CI 1.04–1.23), and opioids (IRR 1.19, 95% CI 1.06–1.34) were significantly associated with the primary composite outcome. Conclusion: The use of specific classes of xerogenic medications was associated with an increased risk for tooth extractions and restorations in people with dementia. The risks and benefits of xerogenic medications, in the context of oral health, should be carefully assessed in this vulnerable population.
Classification of Alzheimer’s Disease with Respect to Physiological Aging with Innovative EEG Biomarkers in a Machine Learning Implementation
Authors: Vecchio Fabrizio , Miraglia Francesca , Alù Francesca , Menna Matteo , Judica Elda , Cotelli Maria , Rossini Paolo Maria 
Published: May 2020

Background: Several studies investigated clinical and instrumental differences to make diagnosis of dementia in general and in Alzheimer’s disease (AD) in particular with the aim to classify, at the individual level, AD patients and healthy controls cooperating with neuropsychological tests for an early diagnosis. Advanced network analysis of electroencephalographic (EEG) rhythms provides information on dynamic brain connectivity and could be used in classification processes. If successfully reached, this goal would add a low-cost, easily accessible, and non-invasive technique with neuropsychological tests. Objective: To investigate the possibility to automatically classify physiological versus pathological aging from cortical sources’ connectivity based on a support vector machine (SVM) applied to EEG small-world parameter. Methods: A total of 295 subjects were recruited: 120 healthy volunteers and 175 AD. Graph theory functions were applied to undirected and weighted networks obtained by lagged linear coherence evaluated by eLORETA. A machine-learning classifier (SVM) was applied. EEG frequency bands were: delta (2–4 Hz), theta (4–8 Hz), alpha1 (8–10.5 Hz), alpha2 (10.5–13 Hz), beta1 (13–20 Hz), beta2 (20–30 Hz), and gamma (30–40 Hz). Results: The receiver operating characteristic curve showed AUC of 0.97±0.03 (indicating very high classification accuracy). The classifier showed 95% ±5% sensitivity, 96% ±3% specificity, and 95% ±3% accuracy for the classification. Conclusion: EEG connectivity analysis via a combination of source/connectivity biomarkers, highly correlating with neuropsychological AD diagnosis, could represent a promising tool in identification of AD patients. This approach represents a low-cost and non-invasive method, one that utilizes widely available techniques which, when combined, reach high sensitivity/specificity and optimal classification accuracy on an individual basis (0.97 of AUC).
Hippocampal Subfield Volumes in Middle-Aged Adults at Risk of Dementia
Authors: McKeever Anna , Paris Alvar F. , Cullen James , Hayes Lawrence , Ritchie Craig W. , Ritchie Karen , Waldman Adam D. , Wells Katie , Busza Albert , Carriere Isabelle , O’Brien John T. , Su Li 
Published: May 2020

Background: Alzheimer’s disease (AD) begins decades before the onset of dementia. There is a need to investigate biomarkers of early AD for use in clinical trials and to facilitate early intervention. Objective: We aimed to determine whether changes in hippocampal subfield volumes in healthy middle-aged adults were associated with risk of future dementia. Methods: We included 150 participants from the PREVENT-Dementia cohort, which recruited subjects aged 40–59 with or without a family history of dementia (FHD; included here were 81 with FHD and 69 without). Hippocampal subfield volumes were segmented from high resolution T2-weighted 3T MRI images taken at baseline and 2-year follow-up. Results: FHD and greater 20 year-risk of dementia due to cardiovascular risk factors were both associated with lower CA1 volume. FHD was also associated with a relative increase in combined CA3, CA4, and dentate gyrus volume between baseline and follow-up. Conclusion: CA1 atrophy may commence as early as middle-age in those with a high risk of future dementia, while increases in CA3, CA4, and dentate gyrus volume may be a response to early AD in the form of inflammation or neurogenesis.
Three-dimensional evaluation of skeletal and dental changes in patients with skeletal class III malocclusion and facial asymmetry after surgical-orthodontic treatment
Authors: Ming Ye , Hu Yun , Wang Tao , Zhang Jiangtao , Li Yuyue , Xu Wenjie , Tan Hao , Ye Huayu , Zheng Leilei 
Published: May 2020

OBJECTIVE: To evaluate skeletal and dental changes in patients with skeletal Class III malocclusion and facial asymmetry after surgical-orthodontic treatment using cone-beam computerized tomography (CBCT). METHODS: This study included forty adult patients diagnosed with skeletal Class III malocclusion and asymmetry who underwent either isolated mandibular surgery or bimaxillary surgery. CBCT scans were taken before treatment (T0), at the completion of presurgical orthodontic treatment (T1) and after treatment (T2). Mimics 17.0 and 3-Matics 7.0 were used to measure skeletal and dental parameters. Skeletal and dental changes within each group from pretreatment to posttreatment were assessed, and Pearson correlation analysis was used to analyze the correlations among skeletal changes. RESULTS: The three-dimensional changes in condylar position were insignificant after surgical-orthodontic treatment in either group ( P > 0.05). However, in the one-jaw surgery group, there were significant backward rotations of the condyle and ramus on the nondeviated side ( P < 0.05), and the condyle on the deviated side rotated inward and forward significantly in the two-jaw surgery group ( P < 0.05) at T2. There were no significant differences in the changes in the total alveolar bone thickness of bilateral first molars during dental decompensation ( P > 0.05). The ratio between the buccal and the total bone thickness around the maxillary first molar on the deviated side decreased significantly at T1, as did those around the mandibular first molar on the nondeviated side ( P < 0.05). CONCLUSIONS: Condylar angulations were less stable after treatment (7 to 9 months after surgery) in both the one-jaw and the two-jaw surgery groups, while condylar displacements were insignificant. In addition, orthodontists should keep a watchful eye to the relative position of the root in the alveolar bone during tooth decompensation.
Analisis Kendala Penyaluran Pembiayaan Mudharabah Pada Bank Syariah di Indonesia
Authors: Yudistira Era 
Published: May 2020

Penyaluran pembiayaan bagi hasil hingga saat ini masih rendah dibandingkan pembiayaan lainnya, terutama jika dibandingkan dengan pembiayaan jual beli seperti murabahah. Namun, dari pembiayaan bagi hasil yang menggunakan akad mudharabah dan musyarakah, akad mudharabah masih sangat jauh perkembangannya dibandingkan dengan musyarakah. Kendala yang terjadi dalam penyalurannya ini, dapat timbul dari keterbatasan SDM yang memahami tentang karakteristik pembiayaan mudharabah, kepedulian bank terhadap keterbatasan nasabah yang diwujudkan dalam bentuk penyusunan strategi bank dalam pengelolaan risiko, dan penerapan standar yang ada tentang pembiayaan mudharabah, ketidakpahaman nasabah terhadap prinsip syariah khususnya mudharabah dan moral hazard yang dilakukan oleh nasabah.
PROJETOS SOLIDÁRIOS: UM CASO DE EXTENSÃO UNIVERSITÁRIA PARA GRUPOS DA TERCEIRA IDADE
Authors: Falcão de Oliveira Carlyle Tadeu , Chavão Norma Suely Da Silva , Correa Priscila Burini 
Published: May 2020

A importância da extensão universitária na articulação do movimento de Economia Solidária para explorar novas alternativas favoráveis ao desenvolvimento social e produtivo, também pode ser pensada para grupos da Terceira Idade. Este artigo, teve como objetivo explorar e descrever um projeto de extensão universitária , no Centro de Convivência da Universidade Aberta da Terceira Idade da Universidade Estadual do Rio de Janeiro (UnATI-UERJ). A relevância do estudo está na reflexão sobre o conceito de Tecnologia Social, no campo da Administração, hoje muito pouco estudado e como ela pode aproximar os saberes da universidade e da sociedade, sob a perspectiva de um futuro mais inclusivo. Para tanto, o estudo procedeu a uma observação-participante durante o curso de extensão universitária denominado Projetos Solidários ministrado na UnATI-UERJ. Os resultados deste projeto de extensão, destacam que a transferência de Tecnologia Social, , pode contribuir para a articulação entre os saberes desenvolvidos no ambiente acadêmico e os saberes locais, visando à formação e capacitação de alunos da terceira idade em economia solidária e projetos comunitários, proporcionando a esses indivíduos um fortalecimento da sua cidadania e perspectivas de melhorias de qualidade de vida
POLÍTICAS GLOBAIS E INFLUÊNCIAS NA AGENDA PARA A FORMAÇÃO SUPERIOR EM SAÚDE NO BRASIL
Authors: Arraes de Alencar Andréa Echeverria 
Published: May 2020

As crescentesalterações políticas, sociais e econômicas das sociedades contemporâneas têm trazido aos sistemas educativos novos desafios, nomeadamente quanto aos modelos, e qualidade, deformação profissional. Focado na problemática da formação superior o presente artigo tem como objetivo compreender influências de políticas globais em currículos locais para formação de profissionais que atuam no campo da saúde no Brasil.Convocam-se contributos de autores que discutem o campo global das políticas educacionais (Rawolle & Lingard, 2013), da abordagem do ciclo de políticas (policy cycle approach) (Ball & Bowe, 2001) e de contribuições de Roger Dale (2004) Education policy e Thomas Popkewitz (2016) conhecimento como prática política.Do ponto de vista metodológico analisam-se relatórios provindos do BM, UNESCO e OCDE publicados entre os anos de 2000 e 2018 e orientações, neles enunciadas, relativas à formação de profissionais de saúde.A análise permitiu constatar que os relatórios contemplam orientações para a formação alinhadas com políticas neoliberais e sintonizadas com o mercado de trabalho. Preconiza-se um perfil de formação voltado para a atenção integral das pessoas, famílias, grupos sociais e comunidades, com aproximação entre serviços de saúde, o contexto local e as instâncias formadoras de profissionais de nível superior. Os resultados apontam ainda para a existência de influências internacionais na agenda da política de Educação Superior no Brasil e nas políticas de Educação em Saúde, em particular.
PENENTUAN INTERVAL PERAWATAN MESIN AIR SEPARATION PLANT SECARA PREVENTIVE DOWNTIME MAINTENANCE DENGAN MENGGUNAKAN METODE AGE REPLACEMENT PADA PT. XYZ
Authors: Fikri Nidaru Ainul , Widjajati Endang Pudji 
Published: May 2020

One way to increase productivity is by reducing downtime on production machine in general, downtime is divided by planned downtime and unplanned downtime. Downtime can be minimized by conducting preventive maintenance. PT. XYZ is a company engaged liquid oksigen, nitrogen and argon manufacturing. In their maintenance system PT. XYZ is still using corrective maintenance method where repair will be conducted if any damage has been occured.
There fore this research is conducted to determine maintenance time interval using age replacement method. This research subject is air sparation plant consists of filter unit, recycle nitrogen compressor unit, and argon purification unit.
Based on the analysis of the results obtained, it is known that with the age replacement method the optimal component replacement time interval for the Argon Purification Unit component is 32,400 minutes, and the Recycle Nitrogen Compressor Unit is 31,500 minutes. with total annual maintenance costs of Rp. 449,921,405. Compared to the cost of maintenance in companies that have a value of Rp 3,115,210,778, the treatment system using the age replacement method is more efficient at 69,23%.
DESAIN EKSPERIMEN PENGARUH VARIASI MEDIA PENDINGIN TERHADAP KEKERASAN DAN KEKUATAN TARIK BAHAN ST 41 PADA PROSES HEAT TREATMENT
Authors: Ayu V Fransisca Diah , Sumiati Sumiati 
Published: May 2020

Baja ST 41 merupakan baja yang tergolong sebagai baja karbon rendah dengan kom-posisi paduan 0,37-0,43%C, 0,5-0,35%Si, 0,60-0,90%Mn. Baja tersebut terkadang memiliki karakter yang tidak sesuai dengan kebutuhan yang diperlukan, sehingga perlu adanya perla-kuan lain untuk merubah sifat dan struktur dari baja ST 41 itu sendiri. Karakteristik baja dapat diubah dengan metode perlakuan panas atau heat treatment, salah satu cara adalah dengan menggunakan metode quenching. Quenching dengan media pendingin tertentu dapat mempengaruhi sifat kekerasan baja ST 41 tersebut. Proses Pemanasan (Normalizing) pada penelitian ini menggunakan suhu 723oC dengan penahanan suhu selama satu jam. Kemudian didinginkan (Quenching) secara cepat dengan berbagai media pendingin. Media pendingin yang digunakan dalam penelitian ini adalah air, air garam, minyak kelapa, dan oli, dengan menggunakan holding time pada masing-masing media pendingin yaitu 5 menit sampai 20 menit. Setelah dilakukan proses quenching, baja ST 41 dilakukan uji kekerasan dan Uji Kekuatan Tarik menggunakan metode uji Rockwell dan di analisis Hasil penelitian ini juga merekomendasikan sebuah persamaan umum untuk memprediksi kekerasan bahan ST 41 apabila menggunakan dua komposisi tersebut, yaitu: Y= 97,2118+0,0983*x-0,4223*y 0,0114*x*x+0,0026*x*y+0,0023 *y*y. Dan Hasil penelitian ini juga merekomendasikan sebuah persamaan umum untuk mempred-iksi kekuatan Tarik bahan ST 41 apabila menggunakan dua komposisi tersebut, yaitu Y = 46,7828+0,3293*x+0,2271*y-0,0132*x*x-1,1689E-14*x*y-0,0009*y*y. Dengan x1 dan x2 mas-ing-masing adalah waktu penahanan dan suhu.

Kata Kunci: Baja ST 41, Holding time, kekerasan dan kekuatan tarik bahan. media Pendingin, suhu.Weights.
Ahlaki Değerlerin “Devlet Sınırları” ve “Göçmen İşçilerin Üyelik Statüsü” Anlamları Üzerine Etkisi
Authors: Sönmez Efe Süreyya 
Published: May 2020

Bu makale, ahlaki değerlerin bölgesel sınırlar ve göçmen işçilerin üyelik statüsü kavramlarının anlamı üzerindeki etkisini ahlaki yapılandırmacı yaklaşım merceğinden incelemektedir. Paylaşılan değerlerin, devletlerin göç politikaları ve kanun yapma süreçlerinin merkezinde yer aldığını önermektedir. Devletler, sadece kolektif bir varlık haline gelen rastgele bir topluluk değil, ortak değerleri olan bireylerden oluşan değer topluluklarıdır. Göçmen işçilerin statüsü, 'değer topluluğuna' üyelikleriyle belirlenir; tartışılabilir bir şekilde, yasal terminolojiyi devlet düzeyinde biçimlendirmek için "geçirgen değerler" ve / veya "geçirimsiz değerler" kullanan kişilerden oluşuyor. Bu makalede, sosyal olarak yapılandırılmış değerlerin devlet politikalarını etkilediği, devlet sınırlarını ve göçmen işçilerin üyelik statülerini tanımladığı sonucuna varılan göç politikasının analizi için Türkiye vaka incelemesine odaklanılmaktadır. Analiz için, Türkiye'de toplanmış görüşmelerden ve katılımcı gözlemlerinden elde edilen birincil veriler ve yasal resmi belgelerdeki ikincil veriler kullanılmıştır.
ABSTRACT IN ENGLISH
The Impact of Moral Values on the Meaning of the Borders and the Membership Status of Migrant Workers
This paper analyses the impact of moral values on the meaning of the concept of territorial borders and the membership status of migrant workers through the lens of the moral constructivist approach. It suggests that shared values sit at the core of the states’ migration policies and law-making processes. States are not merely random collections of people that become a collective being but are communities of value that are consist of individuals who have shared values. Migrant workers’ status is determined by their membership to ‘community of value’ which arguably comprise of persons who use ‘porous values’ and/or ‘impermeable values’ to shape the legal terminology at the state level. The paper focuses on the case study of Turkey for the analysis of migration policy which concludes that socially constructed values influence the state policies and define borders and membership status of migrant workers. For the analysis, it uses primary data from interviews and participant observation; and secondary data from official legal documents collected in Turkey.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS MULTIMEDIA INTERAKTIF MENGGUNAKAN MACROMEDIA DIRECTOR PADA MATERI USAHA DAN ENERGI KELAS X
Authors: Melianti Erina , Risdianto Eko , Swistoro Eko 
Published: May 2020

ABSTRAK Penelitian ini bertujuan untuk (1) menghasilkan media pembelajaran berbasis multimedia interaktif menggunakan Macromedia Director pada materi usaha dan energi kelas X, (2) mendeskripsikan kelayakan pengembangan media pembelajaran berbasis multimedia interaktif menggunakan Macromedia Director pada materi usaha dan energi kelas X. Jenis penelitian ini adalah Research and Development (R&D) level 1 yang dilaksanakan dalam lima tahap yaitu potensi dan masalah, studi literatur dan pengumpulan informasi, desain produk, validasi desain, dan desain teruji. Validasi desain menggunakan angket dan dilakukan oleh ahli. Hasil penelitian menunjukkan bahwa telah dihasilkan media pembelajaran berbasis multimedia interaktif yang berada dalam katergori sangat valid yaitu didapatkan penilaian pada aspek materi dengan presentase 89,58% dinyatakan pada tingkat yang valid, kemudian pada aspek media dengan presentase 84,37% dinyatakan pada tingkat yang valid, dan aspek bahasa dengan presentase 93,33% dinyatakan pada tingkat yang valid. Sehingga didapat bahwa media pembelajaran berbasis multimedia interaktif menggunakan Macromedia Director pada materi usaha dan energi kelas X dikategorikan valid dengan nilai rata-rata 89%.Kata Kunci: Macromedia Director, Multimedia Interaktif, Penelitian Pengembangan ABSTRACT This research was aimed to (1) produce learning media based on interactive multimedia that using macromedia Director on business and energy material at the grade X, (2) describe properness of developing interactive based multimedia learning that using macromedia director in effort and energy material of tenth grade. The type of this research was level 1 of research and development (R&D) was done in five stages namely, potential and problems, literature study and information gathering, product design, design validation, and proven design. Design validation used questionnaires for expert. The result of this research showed that learning media based on interactive multimedia was categoried in valid category for material aspect assessment in percentage 89,58% and then on the media aspect in 84,37% was categoried in valid level, dan language aspect in percentage 93,33% was categoried in valid level. So that it was found that interactive multimedia based learning media using Macromedia Director on business material and energy class X was categorized as valid with an average value of 89%.Keywords: Macromedia Director, Interactive Mutimedia, Research and Development
PENGEMBANGAN DESAIN BAHAN AJAR FISIKA BERBASIS E-MODUL PADA MATERI MOMENTUM
Authors: Shobrina Nadah Qolbi , Sakti Indra , Purwanto Andik 
Published: May 2020

ABSTRAK Penelitian ini bertujuan untuk mengembangkan bahan ajar fisika berbasis E-Modul. Penelitian ini merupakan penelitian pengembangan yang dilaksanakan dalam lima tahapyaitu potensi dan masalah, studi literatur dan pengumpulan informasi, desain produk, validasi desain, dan desain teruji. Sampel atau sumber data penelitian ini yaitu guru fisika dan siswa SMAN 2 Kota Bengkulu kelas X MIPA D. Instrumen yang digunakan dalam penelitian ini yaitu lembar observasi, lembar angket guru dan siswa, lembar angket uji validasi tim ahli. Hasil penelitian menunjukkan bahwa bahan ajar fisika berbasis e-Modul yang dikembangkan termasuk dalam kategori valid dan merupakan desain teruji karena mendapatkan respon positif dengan persentase total uji validitas yaitu 80,6% dan serta memiliki reliabilitas tinggi pada validitas aspek isi dan penyajian dengan nilai koefisien sebesar 0,9 dan 0,88, aspek bahasa nilai koefisien 0,79 dengan kategori sangat tinggi, dan reliabilitas aspek media 0,91 dengan kategori sangat tinggi.Berdasarkanpenelitian pengembangan dan pembahasanyang dilakukan,didapatlahdesainbahanajarfisikaberbasise-modul padamateri momentumdi SMAN 2 KotaBengkuluyangvalid dan reliable. Kata Kunci: Bahan Ajar Fisika, E-Modul, Momentum, Penelitian pengembangan.ABSTRACT This research aimed to develop physics teaching materials based on E-module. This research was is a development research conducted in five stages, namely potention and problem, literature study and information gathering, product design, design validation, and tested design .The sample or data source of this research were the Physic Teacher and Student of SMAN 2 Bengkulu, class of X MIPA D. The instruments used in this research are observation sheet, teacher and student questionnaire, test questionnaire of expert team validation test. The results showed that the e-module based physics teaching materials developed included in the category good validity and as a tested design for getting a positive response with the percentage of total validity test is 80.6% and also had reliability on the content aspect and served with coefficient value equal 0.9 and 0.88, the coefficient value language aspect 0.79 with category very high reliability and reliability media aspect 0,88 with category very high. Based onresearchdevelopmentanddiscussionconducted,resulting ofe-modulematerial design on momentum material at SMAN 2 Bengkuluwas valid and reliable.Keywords: Physics Teaching Material, E-module,Momentum, Research development