bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low annealing temperature effect on Structural, and optical properties of CuO nanostructure thin films
Authors: Omran Alkhayatt Adel H. , Muhammad Shawki Khalaf , Habieb Azher A. , Ali Asala H. , Mohsen Suhad H. , Munem Ruaa Radhi 
Published: June 2020

AbstractIn present work, the modified chemical bath deposition method (CBD) called successive ionic layer adsorption and reaction effective coast method was used for deposited copper oxide CuO nanostructured thin films. Structural, surface texture and optical characteristics of the deposited films were studied as a function of low annealing temperature (150, 200 and 250) °C. X-ray diffraction studies showed that the as-deposited and annealed films exhibited low crystallinity of polycrystalline nature in the monoclinic phase. It is observed a fixed or very little increment of peaks intensity and the crystallinity of the deposited films with the increase of annealing temperature to 250 °C. The lattice constants were calculated and show good agreement with the standard values. The crystallite size was decreased, whereas the dislocation density and the number of crystallites were increased with the increment of annealing temperature. The average grain diameter was increased and the average surface roughness decreased with the increment of annealing temperature. The optical energy gap for the as-deposited film is 1.87eV and increased to (2.03, 2.06 and 2.09) eV with the increment of annealing temperatures. The Urbach tails energy width decreased from 0.91 eV to (0.73, 0.54 and 0.46) eV for as-deposited and annealed films at low temperatures (150, 200 and 250) °C respectively. The low annealing temperatures was used because the deposition process was performs at low temperatures below 100 °C, therefore_it can be concluded that the low annealing temperatures used in this work are not suitable temperatures for the growth of CuO films and it can be above 300 °C to enhance the film crystallinity and formation of CuO phase.
Growth of 3-Dimentional MoS2-PANI nanofiber for high electrochemical performance
Authors: Ganesha H , Veeresh S , Nagaraju Y S , Vandana M , Ashokkumar S P , Vijeth H , Devendrappa H 
Published: June 2020

Abstract
The preparation of few layered 3D material Molybdenum/Polyaniline (MoS2/PANI) nanofiber (NF) composite synthesis via a hydrothermal process. MoS2/PANI nanofiber composite was characterized via Fourier-transform infrared (FT-IR) spectra to study the chemical functional group and their interaction, and optical properties examine by the UV-visible spectra. Formation of nanosheet and 3D hierarchical flower morphology was examined through Field emission scanning electron microscopy (FESEM), and the elemental analysis examined through Energy- dispersive x-ray (EDX), and Transmission electron microscopy (TEM). XRD studies show the properties of crystalline nature of the nanocomposite. Binding energy and composite elemental identified states measured through x-ray photon spectroscopy(X-PS). The Electrochemical technique was used to investigate cyclic voltammetry, and electrochemical catalytic activity evaluated from EIS which obtained resistance is 137.52 Ω, 66.40 Ω, and 15.25 Ω respectively. Linear sweep voltammetry, CV oxidation peak reached maximum oxidation current is 2.72 × 10–4 Amperes, and curve appeared between −4.5 to 4.5 Volt. Finally MoS2-PANI-1 Nanofiber composite is prominent material for electrochemical performance.
rGO/persulfate metal-free catalytic system for the degradation of tetracycline: effect of reaction parameters
Authors: Tran Dinh Trinh , Nguyen Van Noi 
Published: June 2020

Abstract
Reduced graphite oxide (rGO) was synthesized from graphene oxide (GO) by reduction process with the aid of ascorbic acid. GO was synthesized from graphite precursor by modified Hummers method. The prepared materials were characterized in terms of surface morphology, structure, functional group, and elemental compositions by different methods such as SEM/EDS, XRD, FT-IR, Raman, and BET. rGO/K2S2O8 system was used to study the impact of different reaction parameters on the degradation of tetracycline in water. The results showed that GO and rGO materials were successfully synthesized, with high purity. The prepared rGO promoted the degradation of tetracycline by sulphate radicals generated from K2S2O8 with an efficiency of two-fold higher than sole K2S2O8. More than 95% of 5 mg l−1 tetracycline were removed by rGO/K2S2O8 system after 40 min of reaction. The catalytic performance of rGO/K2S2O system in the degradation of tetracycline was dependent on pH of the solution, catalyst loading, tetracycline initial concentration, and persulfate concentration. The optimal conditions for the degradation of tetracycline in water were at pH10, with 5 mg l−1 tetracycline initial concentration, 20 mg l−1 of rGO, and 0.2 mM persulfate added. The catalytic performance of the system showed relatively stable, with about 75% tetracycline in solution were removed after 3 cycles. The degradation of tetracycline by rGO/K2S2O8 system followed the pseudo-first order kinetics, with a typical coefficient of determination above 0.95 for all experimental conditions.
Application of the Environmental Relative Moldiness Index in Indoor Marijuana Grow Operations
Authors: Root Kyle S , Magzamen Sheryl , Sharp Julia L , Reynolds Stephen J , Van Dyke Michael , Schaeffer Joshua W 
Published: June 2020

Abstract

Objectives
Indoor marijuana grow operations (IMGOs) are increasing due to legalization of recreational and medicinal cannabis at the state level. However, the potential exposures of IMGO workers have not been well studied. Mold exposure has been identified as a major occupational health concern. Mold-specific quantitative polymerase chain reaction (MSQPCR) can provide quantitative exposure data for fungi at the species level. The purpose of this study was to characterize the airborne fungal burden using MSQPCR and to evaluate the applicability of an airborne Environmental Relative Moldiness Index (ERMI) in IMGOs.

Methods
Air and dust samples were collected inside and outside the IMGOs and then analyzed via MSQPCR. These data were then used to calculate IMGO-specific ERMI scores. Culturable air samples were collected on agar plates and analyzed via microscopy. Differences were evaluated between indoor and outdoor concentrations, as well as between air and dust samples. The agreement between MSQPCR and culture-based methods was also evaluated.

Results
Based on the geometric means for non-zero values of each fungal species across all IMGOs, the total airborne concentration was approximately 9100 spore equivalent (SE) m−3 with an interquartile range (IQR) of 222 SE m−3. The indoor/outdoor ratio of geometric means across all 36 species per IMGO ranged from 0.4 to 6.2. Significantly higher indoor concentrations of fungal species, including Aspergillus spp., were observed. An average airborne ERMI score of 7 (IQR = 7.6) indicated a relatively high burden of mold across a majority of operations. The ERMI scores were driven by the high concentrations of Group 1 species with a mean of 15.8 and an IQR of 13. There were 63 additional species identified in the culturable air samples not included in the ERMI.

Conclusions
High concentrations of airborne fungi were identified in IMGOs. Our evaluation of the ERMI based on MSQPCR as a rapid diagnostic and risk assessment tool for industrial hygienists in the IMGO setting is equivocal. ERMI did not identify all relevant fungal species associated with this specific occupational environment. We identified several issues with using the ERMI calculation. At this time, the catalog of fungal species needs to optimized for the occupational setting to ensure adequate coverage, especially for those species expected to be found in this burgeoning industry. Further research is necessary to elucidate the link between the ERMI score of airborne samples, worker exposure and health effects in grows to generate an acceptable index score for use in occupational exposure assessments.
AntiCP 2.0: an updated model for predicting anticancer peptides
Authors: Agrawal Piyush , Bhagat Dhruv , Mahalwal Manish , Sharma Neelam , Raghava Gajendra P S 
Published: June 2020

Abstract
Increasing use of therapeutic peptides for treating cancer has received considerable attention of the scientific community in the recent years. The present study describes the in silico model developed for predicting and designing anticancer peptides (ACPs). ACPs residue composition analysis show the preference of A, F, K, L and W. Positional preference analysis revealed that residues A, F and K are favored at N-terminus and residues L and K are preferred at C-terminus. Motif analysis revealed the presence of motifs like LAKLA, AKLAK, FAKL and LAKL in ACPs. Machine learning models were developed using various input features and implementing different machine learning classifiers on two datasets main and alternate dataset. In the case of main dataset, dipeptide composition based ETree classifier model achieved maximum Matthews correlation coefficient (MCC) of 0.51 and 0.83 area under receiver operating characteristics (AUROC) on the training dataset. In the case of alternate dataset, amino acid composition based ETree classifier performed best and achieved the highest MCC of 0.80 and AUROC of 0.97 on the training dataset. Five-fold cross-validation technique was implemented for model training and testing, and their performance was also evaluated on the validation dataset. Best models were implemented in the webserver AntiCP 2.0, which is freely available at https://webs.iiitd.edu.in/raghava/anticp2/. The webserver is compatible with multiple screens such as iPhone, iPad, laptop and android phones. The standalone version of the software is available at GitHub; docker-based container also developed.
Functional Organization for Response Inhibition in the Right Inferior Frontal Cortex of Individual Human Brains
Authors: Suda Akimitsu , Osada Takahiro , Ogawa Akitoshi , Tanaka Masaki , Kamagata Koji , Aoki Shigeki , Hattori Nobutaka , Konishi Seiki 
Published: June 2020

Abstract
The right inferior frontal cortex (IFC) is critical to response inhibition. The right IFC referred in the human studies of response inhibition is located in the posterior part of the inferior frontal gyrus and the surrounding regions and consists of multiple areas that implement distinct functions. Recent studies using resting-state functional connectivity have parcellated the cerebral cortex and revealed across-subject variability of parcel-based cerebrocortical networks. However, how the right IFC of individual brains is functionally organized and what functional properties the IFC parcels possess regarding response inhibition remain elusive. In the present functional magnetic resonance imaging study, precision functional mapping of individual human brains was adopted to the parcels in the right IFC to evaluate their functional properties related to response inhibition. The right IFC consisted of six modules or subsets of subregions, and the spatial organization of the modules varied considerably across subjects. Each module revealed unique characteristics of brain activity and its correlation to behavior related to response inhibition. These results provide updated functional features of the IFC and demonstrate the importance of individual-focused approaches in studying response inhibition in the right IFC.
Long-term overlap of social and genetic structure in free-ranging house mice reveals dynamic seasonal and group size effects
Authors: Evans Julian C , Lindholm Anna K , König Barbara 
Published: June 2020

AbstractAssociating with relatives in social groups can bring benefits such as reduced risk of aggression and increased likelihood of cooperation. Competition among relatives over limited resources, on the other hand, can induce individuals to alter their patterns of association. Population density might further affect the costs and benefits of associating with relatives by altering resource competition or by changing the structure of social groups; preventing easy association with relatives. Consequently, the overlap between genetic and social structure is expected to decrease with increasing population size, as well as during times of increased breeding activity. Here, we use multi-layer network techniques to quantify the similarity between long-term, high resolution genetic, and behavioral data from a large population of free-ranging house mice (Mus musculus domesticus), studied over 10 years. We infer how the benefit of associating with genetically similar individuals might fluctuate in relation to breeding behavior and environmental conditions. We found a clear seasonal effect, with decreased overlap between social and genetic structure during summer months, characterized by high temperatures and high breeding activity. Though the effect of overall population size was relatively weak, we found a clear decrease in the overlap between genetic similarity and social associations within larger groups. As well as longer-term within-group changes, these results reveal population-wide short-term shifts in how individuals associate with relatives. Our study suggests that resource competition modifies the trade-off between the costs and benefits of interacting with relatives.
233Conventional fluoroscopy guided vs zero-fluoroscopy catheter ablation of supraventricular tachycardias
Authors: Prolic Kalinsek T , Pernat A , Jan M , Sorli J , Vrbajnscak M , Sinkovec M , Antolic B , Klemen L 
Published: June 2020

Abstract

Funding Acknowledgements
None
Introduction
Conventionally, catheter movement and placement during catheter ablation (CA) is guided by X-ray fluoroscopy. In recent years, an ‘as low as reasonably possible’ principle was established to minimize the ionizing radiation dose received by the patient and the operator. Zero-fluoroscopy approach is at the extreme end of the spectrum of this principle. With exclusion of X-ray fluoroscopy, three-dimensional electroanatomical mapping system and intracardiac echocardiography are used for catheter guidance during ablation procedures.

Purpose
The aim of our study was to assess and compare procedural parameters and clinical outcomes of conventional X-ray fluoroscopy guided and zero-fluoroscopy CA for treatment of supraventricular tachycardias.

Methods
Retrospective analysis included CA procedure between April 2014 and May 2019. Five hundred and thirteen (513) patients were selected for analysis; they had confirmed diagnosis of atrioventricular nodal reentry tachycardia (AVNRT) or atrioventricular reentry tachycardia (AVRT). Patients were divided into two groups based on the use of fluoroscopy (conventional approach group - CG; zero-fluoroscopy group - ZF). Procedural data and clinical outcomes were analyzed. Two groups were compared using chi-squared test or Mann-Whithney U test when appropriate.

Results
There were 249 patients (44.2% males) in CG group, and 260 patients (47.5% males) in ZF group. ZF group included 113 (43.5%) pediatric patients. The groups differed in mean age (53.4 ± 16.4 years vs 30.0 ± 19.8 years (CG vs ZF), p &lt; 0.001), postprocedural use of antiarrhythmic agents or beta blockers (55.3% vs 17.0% (CG vs ZF), p &lt; 0.001) and type of arrhythmia (72.3% vs 60.6% AVNRT (CG vs ZF), p = 0.003).
In CG group, all procedures were performed using radiofrequency (RF) energy, whereas in ZF group, cryoablation was used in 18.3% of procedures at the discretion of the operator. Mean procedural duration was longer in CG group (100.1 ± 48.8 vs 90.4 ± 83.0 minutes, p &lt; 0.001). The mean fluroscopy time was 13.6 ± 9.3 minutes and mean dose area product was 554.1 ± 713.6 mGycm2 in the CG group. Acute success rate was higher in CG group (95.7 vs 90.7%, p = 0.027). However, the arrhythmia-free survival rate after 13.8 ± 11.0 months of follow-up was lower in the CG group (90.9 vs 96.5%, p = 0.009). Mean number of procedures per patient was 1.04 in the CG group and 1.14 in the ZF group (p &lt; 0.001). There were no severe complications.

Conclusions
Zero-fluoroscopy CA of supraventricular tachycardias is associated with lower procedural success rate, but higher long-term arrhythmia-free survival rate when compared to conventional fluoroscopy guided procedures. It is possible, that these differences are stemming from somewhat different patient populations in both groups.
133Bipolar ablation of refractory ventricular arrhythmias originating from the close proximity of His bundle
Authors: Futyma P R , Ciapala K , Gluszczyk R , Sander J , Futyma M , Kulakowski P 
Published: June 2020

Abstract

Introduction
Biophysics of bipolar radiofrequency catheter ablation (Bi-RFCA) suggest more condensed and selective lesion formation when compared to conventional-unipolar approach. Whether more selective Bi-RFCA can result in safe and effective ablation of arrhythmic substrates in close proximity of His bundle has not been investigated so far.

Purpose
To determine feasibility and effectiveness of Bi-RFCA in His bundle area.

Methods
Consecutive patients after failed unipolar ablation for symptomatic premature ventricular complexes (PVC) or ventricular tachycardia (VT) originating from the vincity of His bundle underwent Bi-RFCA.

Results
We ultimately enrolled 8 patients (2 females, age 60 ± 15 years) to undergo Bi-RFCA of PVC/VT. Previous pharmacological treatment consisting of at least one antiarrhythmic drug and conventional catheter ablation failed in all. Bi-RFCA using open-irrigated and non-irrigated ablation catheters (AC) was delivered from two earliest PVC/VT activation sites located in the vincity of His bundle (Figure, panels A-B). A total number of 93 bipolar applications were delivered (mean bipolar RF time 508 ± 565s, mean power 35 ± 13W, mean impedance 163 ± 18Ω). Transient conduction disturbances occurred in 2 patients and were associated with mechanical compression of conduction system. No persistent conduction disturbances occurred. Bipolar RFCA led to acute elimination of PVC/VT in 6 (75%) patients. Follow up lasted 11 ± 5 months: two patients underwent repeat procedure using dual-irrigated Bi-RFCA, there was no VT recurrence and 72% PVC burden reduction was achieved (16200 ± 11600 pre-ablation vs 4500 ± 6200 post-ablation PVC/day, p = 0,035) (Figure, panel C).

Conclusion
Bi-RFCA performed in proximity of His bundle can be safe and effective in majority of patients.
Abstract Figure. Bipolar ablation of parahisian PVC/VT
P568Catheter ablation for atrial fibrillation with heart failure with preserved ejection fraction
Authors: Rattka M , Kuehberger A , Stephan T , Weinmann K , Felbel D , Baumhardt M , Bothner C , Pott A , Dahme T 
Published: June 2020

Abstract

Background
Atrial fibrillation (AF) in patients suffering from heart failure with preserved ejection fraction (HFpEF) is associated with increased symptoms and higher morbidity and mortality. Effective treatment strategies for this patient population have not yet been established.

Aim
This study aimed to compare the impact of catheter ablation for AF against the current standard therapy on patients with HFpEF.

Methods
We retrospectively compared clinical outcomes and echocardiographic parameters of patients with AF and HFpEF, who either underwent medical therapy (rate or rhythm control) or catheter ablation for AF. The primary endpoint was a composite of death and hospitalization for any cause and the secondary endpoint a composite of cardiovascular death and cardiovascular hospitalization. Additionally, we assessed NYHA-class, relevant echocardiographic parameters, current ESC diagnosis criteria for HFpEF at baseline and at the end of follow-up, as well as time-to-AF recurrence in both groups. Resolution of HFpEF was estimated, if both left ventricular mass index(LVMI) and E/e’ ratio did not fulfil the ESC-criteria at the end of follow-up.

Results
Between January 2013 and December 2018 6.114 patients were treated for AF at our university hospital department. Of those, 752 patients suffered from heart failure symptoms and had echocardiographic diastolic dysfunction. Applying the current ESC-criteria HFpEF was diagnosed in 127 patients. While 59 patients received medical therapy only, catheter ablation for AF was performed in 68 patients. Analysis of AF recurrence in both groups revealed, that in the ablation group 82% of patients and in the medical therapy group only 25% of patients were free from any atrial arrhythmia after one year. Reevaluation of echocardiographic parameters after a mean follow-up period of 39 ± 20 months showed no difference in the medical therapy group, but revealed a significant improvement of the mitral E-wave velocity, E/E’ ratio, LVMI, interventricular septal thickness, e’ velocity and left ventricular diastolic in the catheter therapy group, suggesting reverse remodeling. Reassessment of criteria for HFpEF diagnosis showed resolution of HFpEF in 35% of invasively treated patients compared to 12% of patients who received conservative therapy only (p = 0.002). Moreover, heart failure symptoms, monitored by NYHA-class, significantly worsened in the medical therapy group, whereas there was significant improvement after catheter ablation. Furthermore, assessment of the primary and secondary endpoint displayed significant lower rates of events.

Conclusion
This is the first study comparing the effect of catheter ablation for AF with the current standard therapy in patients with concomitant HFpEF. Our results suggest that catheter ablation is able to induce reverse remodeling of HFpEF, possibly thereby reducing typical heart failure symptoms and hospitalizations.