bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Coordination Number and Geometry in Controlling the Magnetic Anisotropy in FeII, CoII, and NiII Single‐Ion Magnets
Authors: Sarkar Arup , Dey Sourav , Rajaraman Gopalan 
Published: July 2020

AbstractSince the last decade, the focus in the area of single‐molecule magnets (SMMs) has been shifting constructively towards the development of single‐ion magnets (SIMs) based on transition metals and lanthanides. Although ground‐breaking results have been witnessed for DyIII‐based SIMs, significant results have also been obtained for some mononuclear transition metal SIMs. Among others, studies based on CoII ion are very prominent as they often exhibit high magnetic anisotropy or zero‐field splitting parameters and offer a large barrier height for magnetisation reversal. Although CoII possibly holds the record for having the largest number of zero‐field SIMs known for any transition metal ion, controlling the magnetic anisotropy in these systems are is still a challenge. In addition to the modern spectroscopic techniques, theoretical studies, especially ab initio CASSCF/NEVPT2 approaches, have been used to uncover the electronic structure of various CoII SIMs. In this article, with some selected examples, the aim is to showcase how varying the coordination number from two to eight, and the geometry around the CoII centre alters the magnetic anisotropy. This offers some design principles for the experimentalists to target new generation SIMs based on the CoII ion. Additionally, some important FeII/FeIII and NiII complexes exhibiting large magnetic anisotropy and SIM properties are also discussed.
COVID‐19 outcomes of patients with gynecologic cancer in New York City
Authors: Lara Olivia D. , O’Cearbhaill Roisin E. , Smith Maria J. , Sutter Megan E. , Knisely Anne , McEachron Jennifer , Gabor Lisa R. , Jee Justin , Fehniger Julia E. , Lee Yi‐Chun , Isani Sara S. , Wright Jason D. , Pothuri Bhavana 
Published: July 2020

BackgroundNew York City (NYC) is the epicenter of severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID‐19]) in the United States. Clinical characteristics and outcomes of vulnerable populations, such as those with gynecologic cancer who develop COVID‐19 infections, is limited.MethodsPatients from 6 NYC‐area hospital systems with known gynecologic cancer and a COVID‐19 diagnosis were identified. Demographic and clinical outcome data were abstracted through a review of electronic medical records.ResultsRecords for 121 patients with gynecologic cancer and COVID‐19 were abstracted; the median age at the COVID‐19 diagnosis was 64.0 years (interquartile range, 51.0‐73.0 years). Sixty‐six of the 121 patients (54.5%) required hospitalization; among the hospitalized patients, 45 (68.2%) required respiratory intervention, 20 (30.3%) were admitted to the intensive care unit, and 9 (13.6%) underwent invasive mechanical ventilation. Seventeen patients (14.0%) died of COVID‐19 complications. No patient requiring mechanical ventilation survived. On multivariable analysis, hospitalization was associated with an age ≥64 years (risk ratio [RR], 1.73; 95% confidence interval [CI], 1.18‐2.51), African American race (RR, 1.56; 95% CI, 1.13‐2.15), and 3 or more comorbidities (RR, 1.43; 95% CI, 1.03‐1.98). Only recent immunotherapy use (RR, 3.49; 95% CI, 1.08‐11.27) was associated with death due to COVID‐19 on multivariable analysis; chemotherapy treatment and recent major surgery were not predictive of COVID‐19 severity or mortality.ConclusionsThe case fatality rate among gynecologic oncology patients with a COVID‐19 infection is 14.0%. Recent immunotherapy use is associated with an increased risk of mortality related to COVID‐19 infection.Lay Summary

The case fatality rate among gynecologic oncology patients with a coronavirus disease 2019 (COVID‐19) infection is 14.0%; there is no association between cytotoxic chemotherapy and cancer‐directed surgery and COVID‐19 severity or death.

As such, patients can be counseled regarding the safety of continued anticancer treatments during the pandemic. This is important because the ability to continue cancer therapies for cancer control and cure is critical.
Aortic root thrombus after left ventricular assist device implantation and aortic valve replacement
Authors: Veenis Jesse F. , Brugts Jasper J. , Yalcin Yunus C. , Roest Stefan , Bekkers Jos A. , Manintveld Olivier C. , Constantinescu Alina A. , Bogers Ad J.J.C. , Zijlstra Felix , Caliskan Kadir 
Published: July 2020

AbstractData on the risk of aortic root thrombosis in patients with aortic valve replacement (AVR) and left ventricular assist device (LVAD) surgery are scarce. Two out of nine patients receiving AVR concomitant with LVAD surgery and two out of two patients receiving AVR on LVAD support, at our centre, developed an aortic root thrombus, all diagnosed with computed tomography (CT) angiography. These results demonstrate that patients with concomitant AVR and LVAD surgery, or AVR on LVAD support, have an increased risk of aortic root thrombosis. Therefore, early anti‐thrombotic therapy and vigilant diagnostic follow‐up, using CT scans, are warranted to prevent thromboembolic events.
Unveiling outcomes in coexisting severe aortic stenosis and transthyretin cardiac amyloidosis
Authors: Rosenblum Hannah , Masri Ahmad , Narotsky David L. , Goldsmith Jeff , Hamid Nadira , Hahn Rebecca T. , Kodali Susheel , Vahl Torsten , Nazif Tamim , Khalique Omar K. , Bokhari Sabahat , Soman Prem , Cavalcante João L. , Maurer Mathew S. , Castaño Adam 
Published: July 2020

AbstractAimsAdvances in diagnostic imaging have increased the recognition of coexisting transthyretin cardiac amyloidosis (ATTR‐CA) and severe aortic stenosis (AS), with a reported prevalence between 8–16%. In this prospective study, we aimed to evaluate the implications of ATTR‐CA on outcomes after transcatheter aortic valve replacement (TAVR).Methods and resultsAt two academic centres, we screened patients with severe AS undergoing TAVR for ATTR‐CA. Using Kaplan–Meier analysis, we compared survival free from death and a combined endpoint of death and first heart failure hospitalization between patients with and without ATTR‐CA. Cox proportional‐hazards models were used to determine the association of ATTR‐CA with these endpoints. The rate of heart failure hospitalization was compared amongst those with and without ATTR‐CA. Overall, 204 patients (83 years, 65% male, Society of Thoracic Surgeons score 6.6%, 72% New York Heart Association class III/IV) were included, 27 (13%) with ATTR‐CA. Over a median follow‐up of 2.04 years, there was no difference in mortality (log rank, P = 0.99) or the combined endpoint (log rank, P = 0.79) between patients with and without ATTR‐CA. In Cox proportional‐hazards models, the presence of ATTR‐CA was not associated with death. However, patients with ATTR‐CA had increased rates of heart failure hospitalization at 1 year (0.372 vs. 0.114 events/person‐year, P < 0.004) and 3 years (0.199 vs. 0.111 events/person‐year, P = 0.087) following TAVR.ConclusionIn moderate‐risk patients with severe AS undergoing TAVR, there was a 13% prevalence of ATTR‐CA, which did not affect mortality. The observed increase in heart failure hospitalization following TAVR in those with ATTR‐CA suggests the consequences of the underlying infiltrative myopathy.
Spatiotemporal graph convolutional recurrent networks for traffic matrix prediction
Authors: Zhao Jianlong , Qu Hua , Zhao Jihong , Dai Huijun , Jiang Dingchao 
Published: July 2020

SummaryThrough accurate network‐wide traffic prediction, network operators can agilely manage resources and improve robustness by proactively adapting to new traffic patterns, especially for traffic engineering, capacity planning and quality of service provisioning. However, due to the proliferation of backbone network traffic as well as the complexity and dynamics of network communication behavior, accurate and effective network‐wide traffic prediction is challenging. To address the challenges, this paper focuses on short‐term traffic matrix (TM) prediction in large‐scale IP backbone networks. In order to improve the prediction performance, a novel spatiotemporal graph convolutional recurrent network (SGCRN)—a deep learning framework that incorporates both spatial and temporal dependencies of traffic flows, is proposed to implement TM prediction with high accuracy and efficiency. By learning network‐wide traffic as graph‐structured TM time series, SGCRN jointly utilizes graph convolutional networks (GCN) and gated recurrent units (GRU) networks to extract comprehensive spatiotemporal correlations among traffic flows. Specifically, SGCRN employs GCNs to identify structural spatial features of traffic flows by considering topological properties, and utilizes GRUs to implement temporal features learning by considering short and long‐term dynamics of traffic flows. Extensive experimental results on the inter‐Points of Presence network traffic data from four real IP backbone networks show that SGCRN can effectively predict short‐term network‐wide TM with superior accuracy compared with other four widely used traffic prediction methods.
Soft furnishing fires: They're still a problem
Authors: Ahrens Marty 
Published: July 2020

SummaryHome fires in which soft furnishings were first ignited or contributed to fire spread cause a disproportionate share of US home fire deaths. Although the death toll from these fires is much lower than in the 1980s, the rate of death per 1000 reported fires has doubled. Data from the National Fire Incident Reporting System and the National Fire Protection Association's annual Fire Experience Survey were used to create national estimates of these fires and casualties. Including both fires in which upholstered furniture was the item first ignited and contributed most to fire spread, in 2013‐2017, upholstered furniture was involved in an estimated average of 7120 (2%) home fires per year, resulting in an average of 570 (22%) deaths per year. Mattresses or bedding were involved in estimated average of 10 530 (3%) home fires per year, resulting in an average of 370 (14%) deaths annually. In most of these fires and deaths, the item was first ignited. Smoking materials were the leading cause of these fires (20%‐26%) and associated deaths (52%‐54%). Various types of operating equipment and small open flames also play a role. Understanding the causes of these fires is essential to develop new strategies to prevent them.
The effect of pH on the chemical and structural interactions between apple polyphenol and starch derived from rice and maize
Authors: Chou Shurui , Li Bin , Tan Hui , Zhang Weijia , Zang Zhihuan , Cui Huijun , Wang Hanchen , Zhang Shuyi , Meng Xianjun 
Published: July 2020

AbstractTo date, how pH affects starch–polyphenol mixtures has not been thoroughly investigated. This study explored the impact of combining apple polyphenol (AP) with both normal rice starch (NRS) and normal maize starch (NMS) across a range of pH conditions. NRS–AP mixture particle sizes across a pH range of 3–8 varied from 169.9 ± 5.4 to 187.5 ± 6.9 μm, while for NMS–AP particles, these sizes ranged from 161.8 ± 8.0 to 176.0 ± 4.9 μm, indicating that the aggregation of starch–AP was inhibited under low pH condition. The melting enthalpy (△H) values of the NRS–AP mixture across a pH range of 3–8 were 8.50 ± 0.06–9.56 ± 0.12 J/g, while the corresponding value for the NMS–AP mixture was 5.77 ± 0.05–6.21 ± 0.08 J/g. FTIR analyses revealed that the degree of order of these starch–AP mixtures significantly decreased under low pH conditions. XRD analysis further revealed that both NRS–AP and NMS–AP mixtures exhibited V‐type structures, and relative crystallinity levels decreased significantly under low pH conditions. Together, these results indicate that low pH values inhibit the recrystallization of NRS–AP and NMS–AP mixtures. Overall, these findings provide additional evidence regarding the interactions between AP and specific starches under a range of pH conditions.
Effect of Structural Defects and Impurities on the Excited State Dynamics of 2D BA2PbI4 Perovskite
Authors: Gélvez‐Rueda María C. , Peeters Sicco , Wang Peng‐Cheng , Felter Kevin M. , Grozema Ferdinand C. 
Published: July 2020

AbstractIn this work, we show that the quality of the precursor and the thin film preparation strongly affect the optoelectronic properties of the 2D perovskite BA2PbI4. 2D perovskites with alkylammonium organic cations such as butylammonium (BA) are relatively soft structures that exhibit large dynamic disorder and phase variations. Here we show, by a variety of spectroscopy techniques (steady state absorption, photoluminescence and ultrafast transient absorption), that at temperatures below the phase transition (253 K) the material exhibits excitonic features from the room temperature phase (due to incomplete structural transition) and a broadband emission at 560–600 nm (due to self‐trapped excitons) with varied relative intensities depending on the precursors and processing conditions. This suggests that the processing conditions have a large influence on the crystallization and introduction of extrinsic defect impurities directly affecting the optoelectronic properties. Making absolute statements about the properties of BA2PbI4 requires improved control over the materials thin film deposition and a better understanding of the role of the lattice vibrational dynamics and extrinsic defects on the exciton dynamics.
Exact solutions of micropolar SWCNTs nanofluid with heat transfer
Authors: Irfan Haider Muhammad , Imran Asjad Muhammad , Aleem Maryam , Hussanan Abid 
Published: July 2020

AbstractThe present study is aimed to analyze the unsteady micropolar nanofluid flow passing over an oscillating infinite vertical plate. The flow is affected by thermal radiation and Newtonian heating. Single‐walled carbon nanotubes (SWCNTs) are added to enrich the thermal properties of the micropolar fluid. Kerosene is taken as the base liquid to enhance heat transfer. By using dimensional analysis, the governing equations for temperature, velocity, and microrotation are reduced to dimensionless form and after that, these equations have been solved by applying Laplace transform method to get the exact solutions. Finally, we have presented the effects of material and flow parameters and illustrated graphically by the Mathcad software. We found that microrotation, temperature, and velocity are decreasing functions of Prandtl number but have shown increasing behavior for Grashof number. Furthermore, we found that SWCNTs‐water‐based nanofluid has a comparatively higher heat transfer rate than SWCNTs‐kerosene and SWCNTs‐engine oil‐based nanofluids.
Do the macroeconomic factors influence the firm's investment decisions? A generalized method of moments (GMM) approach
Authors: Farooq Umar , Ahmed Jaleel , Khan Shamshair 
Published: July 2020

AbstractThe study checks association between the macroeconomic factors and corporate investment decision by using 10 years of data (2007–2016) of 12 Asian countries. There exist the series of studies, which discuss the firm‐level determinants of investment but very few studies have found the relationship between macroeconomic factors and corporate investment. So, with specific data set, this study is an attempt to fill this instant gap by exploring the relationship between macroeconomic factors and firm capital investment. GMM approach uses for estimation purposes. The results imply that increases in inflation rate decrease the investment due to increment in future cost of investment. Similarly, high interest rate decreases the corporate capital investment due to opportunistic options of early returns by investing in high interest income securities. The firms from high GDP growth countries carry higher investment level owing to business acceleration. However, the firms from high FDI inflow countries bear the low investment opportunities attributed to suppressed fierce competition. The countries having developed financial sector encourage their firms to invest more in banking securities instead of investing in physical long‐term investment, that is, investment in fixed assets due to professional management of funds by financial institutions and low substantial risks. Briefly, the findings of the study recommend that the corporate managers should focus on economic sensitivity while making decisions about any potential investment.
Suppuration as diagnostic criterium of peri‐implantitis
Authors: Monje Alberto , Vera Maria , Muñoz‐Sanz Agustín , Wang Hom‐Lay , Nart José 
Published: July 2020

AbstractBackgroundSuppuration (SUP) as a diagnostic parameter for monitoring dental implants is not yet well understood. The retrospective clinical and radiographic study was therefore performed to investigate the patient, implant, and site characteristics among individuals exhibiting SUP.MethodsDemographic characteristics and clinical parameters were recorded. Radiographic features were analyzed using cone‐beam computed tomography. Peri‐implantitis was defined based on the consensus report of Workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions: probing depth (PD) ≥6 mm, presence of bleeding and/or SUP on gentle probing, and radiographic marginal bone loss (MBL) ≥3 mm. SUP was graded according to profuseness (dot versus line/drop) and time after probing (≥15 seconds versus <15 seconds after probing versus spontaneous). Simple binary logistic regression models were estimated using generalized estimation equations to explain the probability of SUP based on demographic, clinical, and radiographic variables.ResultsA total of 111 eligible patients (nimplants = 501) were assessed. Of them, 57 (nimplants = 334) were diagnosed with peri‐implantitis according to the established case definition, and of these individuals, 31 (nimplants = 96) presented SUP. Therefore, the prevalence of SUP was 27.92% in the total sample size and 54.38% in peri‐implantitis patients. Overall, 28.74% implants displayed SUP within patients with peri‐implantitis. SUP was more frequently found at buccal sites (51%) and proved less prevalent at mesio‐lingual sites (16.7%). Defect morphology (OR = 6.59; P = 0.004), PD (OR = 1.63; P = 0.024), and MBL (OR = 1.35; P = 0.010) were significantly associated with the presence of SUP. Likewise, defect morphology (P = 0.02), PD (P = 0.003), and MBL (P = 0.01) were significantly correlated with the grade of SUP.ConclusionThe presence and grade of SUP are associated with peri‐implant bone loss, probing depth, and defect morphology in patients with peri‐implantitis.
Iron overload as a risk factor for poor graft function following allogeneic hematopoietic stem cell transplantation
Authors: Wu Xue‐Qiong , Lin Kang‐Ni , Chen Min‐Min , Jiang Pei‐Fang , Zhang Yu‐Xin , Chen Yong‐Quan , Chen Qiu‐Ru , Xiao Min , Zhu Hao‐Jie , Issa Hajji Ally , Chen Shao‐Zhen , Luo Xiao‐Feng , Ren Jin‐Hua , Li Qian , Zeng Yan‐Ling , Xu Jing‐Jing , Lin Yi‐Feng , Zheng Rong , Zheng Zhi‐Hong , Chen Zhi‐Zhe , Hu Jian‐Da , Yang Ting 
Published: July 2020

AbstractHematological malignancies are increasingly treated with allogeneic hematopoietic stem cell transplantation (allo‐HSCT). Unfortunately, iron overload is a frequent adverse effect of allo‐HSCT and is associated with poor prognosis. In the present study, we investigated hematopoiesis in iron‐overloaded mice and elucidated the effects of iron overload on the bone marrow (BM) microenvironment. Iron‐overloaded BALB/C mice were generated by injecting 20 mg/mL saccharated iron oxide intraperitoneally. Hematoxylin‐eosin staining was performed to evaluate the effects of an iron overload in mice. BM cells obtained from C57BL/6 mice were transplanted into irradiated BALB/C mice (whole‐body irradiation of 4 Gy, twice with a 4‐hours interval) by tail vein injection. Two weeks after allo‐HSCT, the hematopoietic reconstitution capacity was evaluated in recipients by colony‐forming assays. Histopathological examinations showed brown‐stained granular deposits, irregularly arranged lymphocytes in the liver tissues, and blue‐stained blocks in the BM collected from mice received injections of high‐dose saccharated iron oxide (20 mg/mL). Iron‐overloaded mice showed more platelets, higher‐hemoglobin (HGB) concentration, fewer granulocyte‐macrophage colony‐forming units (CFU‐GM), erythrocyte colony‐forming units (CFU‐E), and mixed granulocyte/erythrocyte/monocyte/megakaryocyte colony‐forming units (CFU‐mix) than healthy mice. Iron‐overloaded recipients presented with reduced erythrocytes and HGB concentration in peripheral blood, along with decreased marrow stroma cells, CFU‐GM, CFU‐E, and CFU‐mix relative to healthy recipients. Taken together, our findings demonstrate that iron overload might alter the number of red blood cells after transplantation in mice by destroying the BM microenvironment, thereby affecting the recovery of BM hematopoietic function.
Sequence‐Controlled Synthesis of Advanced Clickable Synthetic Oligonucleotides
Authors: Han Xun , Fairbanks Benjamin D. , Sinha Jasmine , Bowman Christopher N. 
Published: July 2020

AbstractThrough thiol‐ene photopolymerization of presynthesized oligomers, advanced clickable nucleic acids (CNA‐2G) are synthesized with sequence‐controlled repeating units. As examples, poly(thymine‐adenine) (polyTA) CNA‐2G and poly(thymine‐thymine‐cytosine) CNA‐2G are synthesized by polymerizing thiol‐ene heterofunctional dimers with pendant thymine‐adenine nucleobases and trimer with pendant thymine‐thymine‐cytosine nucleobases. Based on size exclusion chromatography (SEC) analysis, polyTA and polyTTC have number average molecular weights of 2000 and 1800, respectively, which contain 7–8 pendant nucleobases. Based on the different behavior of the CNA‐2G monomers and CNA‐2G oligomers with two or more pendant nucleobases in photopolymerization, an unusual thiol‐ene chain‐growth propagation mechanism is observed for the former and a common thiol‐ene step‐growth propagation mechanism for the latter. The uncommon thiol‐ene chain‐growth propagation is hypothesized to rely on a six‐membered ring mediated intramolecular hydrogen atom transfer process.
Intravenous ferric carboxymaltose for iron deficiency anemia or iron deficiency without anemia after poor response to oral iron treatment: Benefits and risks in a cohort of 144 children and adolescents
Authors: Ozsahin Hulya , Schaeppi Michela , Bernimoulin Michael , Allard Magali , Guidard Clémence , van den Ouweland Frank 
Published: July 2020

AbstractObjectiveThe objective of this single‐center observational study was to determine the clinical and hematologic responses to intravenous ferric carboxymaltose (FCM) in a cohort of pediatric patients with poor response to oral iron therapy. The occurrence of adverse events was systematically recorded for up to 96 hours after infusion.Study designA retrospective cohort of 144 consecutive patients aged 18 months to < 18 years with iron deficiency anemia (IDA) or iron deficiency (ID) without anemia was investigated. All patients had failed oral iron therapy. The assessments before and after FCM treatment followed a predefined protocol.ResultsOne hundred of 117 (85 %) of patients with complete data achieved the target ferritin level ≥ 30 µg/L after a single FCM dose. Of 77 patients with IDA and complete data, 38 (49%) showed a complete hematological response within 6‐12 weeks; a complete or partial response was achieved by 83%. Clinical symptoms improved in 85% of all patients. In 92% of patients (n = 133 /144), FCM infusion was uneventful. During the 96‐hour follow‐up, five patients reported potentially related symptoms. No serious adverse events occurred.ConclusionThe study confirms the safety and efficacy of FCM in children (aged 18 months and older) and adolescents unresponsive to oral therapy, in real‐world experience. Single‐dose FCM treatment was followed by clinical improvement with advantages of safety, compliance, and lower cost compared with previous generation parenteral iron preparations that had to be administered in fractionated sessions.