bluuebunny/crossref_metadata_2025_split huggingface dataset:
The political imaginaries of blockchain projects: discerning the expressions of an emerging ecosystem
Authors: Husain Syed Omer , Franklin Alex , Roep Dirk 
Published: February 2020

AbstractThere is a wealth of information, hype around, and research into blockchain’s ‘disruptive’ and ‘transformative’ potential concerning every industry. However, there is an absence of scholarly attention given to identifying and analyzing the political premises and consequences of blockchain projects. Through digital ethnography and participatory action research, this article shows how blockchain experiments personify ‘prefigurative politics’ by design: they embody the politics and power structures which they want to enable in society. By showing how these prefigurative embodiments are informed and determined by the underlying political imaginaries, the article proposes a basic typology of blockchain projects. Furthermore, it outlines a frame to question, cluster, and analyze the expressions of political imaginaries intrinsic to the design and operationalization of blockchain projects on three analytic levels: users, intermediaries, and institutions.
Evaluation of Ultrasound Pretreatment for Enhanced Anaerobic Digestion of Sida hermaphrodita
Authors: Marta Kisielewska , Paulina Rusanowska , Magda Dudek , Anna Nowicka , Aleksandra Krzywik , Marcin Dębowski , Kazimierowicz Joanna , Marcin Zieliński 
Published: February 2020

AbstractThe influence of ultrasonic pretreatment with specific energy input ranging from 25 to 550 kJ/kg volatile solids on the mixture of Sida hermaphrodita (L.) Rusby mixed with cattle manure disintegration and subsequent anaerobic digestion was assessed. The pretreatment process led to significant increase in the biomass solubility by 21.9% as chemical oxygen demand and enhanced biogas yield by 157% (567.1 L biogas/kg volatile solids) when the specific energy input was from 200 to 550 kJ/kg. However, only pretreatments where ultrasound was applied at 25–50 kJ/kg led to positive net energy gain, indicating that the biomass processing with this method does not always compensate the energy consumption for irradiation.
Probabilistic assessment of API casing strength in serviceability limit state
Authors: Gouveia L. P. , Lima Junior E. T. , Santos J. P. L. , Lira W. W. M. , Anjos J. L. R. , Oliveira F. L. 
Published: February 2020

AbstractThis paper addresses the probabilistic analysis of casing tubulars, regarding the failure modes defined in API 5C3 code, which refers to the violation of elastic regime due to internal and external pressures, and axial force. The casing system performs important structural and isolation functions, ensuring the well integrity through its life cycle. The reliability-based casing design handles rigorously the uncertainties associated with the tube manufacturing, as variations in geometrical and mechanical properties, allowing to evaluate the probability of failure. It is presented a parametric analysis over different steel grades and tube slenderness, besides the application to a design scenario, by using Monte Carlo simulation and first-order reliability method. The results indicate that: collapse is the dominant failure mode; wall thickness and the yield limit govern the probabilistic response; the triaxial envelopes, revisited in a probabilistic framework, consist in a powerful tool, supporting the decision-making process in casing design.
Evaluation of the clinical impact of repeat application of hydrogel-forming microneedle array patches
Authors: Al-Kasasbeh Rehan , Brady Aaron J. , Courtenay Aaron J. , Larrañeta Eneko , McCrudden Maelíosa T.C. , O’Kane Donal , Liggett Stephen , Donnelly Ryan F. 
Published: February 2020

AbstractHydrogel-forming microneedle array patches (MAPs) have been proposed as viable clinical tools for patient monitoring purposes, providing an alternative to traditional methods of sample acquisition, such as venepuncture and intradermal sampling. They are also undergoing investigation in the management of non-melanoma skin cancers. In contrast to drug or vaccine delivery, when only a small number of MAP applications would be required, hydrogel MAPs utilised for sampling purposes or for tumour eradication would necessitate regular, repeat applications. Therefore, the current study was designed to address one of the key translational aspects of MAP development, namely patient safety. We demonstrate, for the first time in human volunteers, that repeat MAP application and wear does not lead to prolonged skin reactions or prolonged disruption of skin barrier function. Importantly, concentrations of specific systemic biomarkers of inflammation (C-reactive protein (CRP); tumour necrosis factor-α (TNF-α)); infection (interleukin-1β (IL-1β); allergy (immunoglobulin E (IgE)) and immunity (immunoglobulin G (IgG)) were all recorded over the course of this fixed study period. No biomarker concentrations above the normal, documented adult ranges were recorded over the course of the study, indicating that no systemic reactions had been initiated in volunteers. Building upon the results of this study, which serve to highlight the safety of our hydrogel MAP, we are actively working towards CE marking of our MAP technology as a medical device.
On the Simulation of 3D Printing Process by a Novel Meshless Analysis Procedure
Authors: Mao Ying , Chen Wen-Hwa , Lee Ming-Hisao 
Published: February 2020

ABSTRACTTo evaluate the thermal deformation induced by 3D Printing (Three Dimensional Printing) process, a novel meshless analysis procedure is established. To account for the heat transfer and solidification effects of each printing layer from liquid to solid phase transition, the layer temperature is measured by the implanted thermocouples. Based on the temperature variation measured, the printing layer temperature can be averaged and considered as uniform for thermal analysis. In addition, as observed by the deformation of the printed target through experiment, only linear thermal elastic analysis is performed.A rigorous algorithm for simulating the 3D Printing process is presented herein. Since the interpolation functions are no longer polynomials, a simple integration scheme using uniform integration points is applied to calculate the global stiffness matrix. Thus, the density and location of the integration points can be easily adjusted to fulfill the required accuracy. Further, for practical implementation, the simulation is also carried out by the concept of equivalent layer.Demonstrative cases of printing a rectangular PLA (Polylactic Acid) brick are tackled to prove the accuracy and efficiency of the proposed meshless analysis procedure. The effects of layer thickness, equivalent layer and slenderness ratio on the thermal deformation of the printed brick are also investigated.
Breakfast skipping is related to inadequacy of vitamin and mineral intakes among Japanese female junior high school students: a cross-sectional study
Authors: Matsumoto Mai , Hatamoto Yoichi , Sakamoto Azusa , Masumoto Ayumi , Ikemoto Shinji 
Published: February 2020

Abstract
Breakfast skipping is a public health issue which affects nutrient intake among adolescents worldwide. However, there have been few reports comparing intake and reference values to assess the deficiency of nutrient intake between breakfast consumers and skippers. Therefore, the present study aimed to examine the relationship between breakfast skipping and adequacy of total habitual nutrient intake among junior high school female students. The participants were 516 Japanese female junior high school students. Dietary habits during the preceding month were assessed using a brief self-administered diet history questionnaire. Inadequacy of each nutrient intake was assessed by the cut-point method, based on the estimated average requirement for fourteen nutrients and on dietary goal values for five nutrients. The overall nutritional inadequacy in participants was assessed by the number of consumed nutrients which did not meet the requirements as per the dietary reference intakes for Japanese, 2015 version. The participants were classified into two groups according to the frequency of breakfast eating: breakfast consumers (seven times/week) and breakfast skippers (0–6 times/week). Adequacy of vitamin A, vitamin B1, vitamin B2, vitamin C, Ca, Fe, Zn and K was higher among breakfast consumers than among skippers. Breakfast consumers had more intakes of fruits, vegetables and dairy products. Our findings suggest that breakfast skipping was related to deficiencies in vitamin and mineral intakes, and to an unfavourable dietary pattern, among Japanese female junior high school students.
Childhood dietary patterns and body composition at age 6 years: the Children of Screening for Pregnancy Endpoints (SCOPE) study
Authors: Flynn Angela C. , Thompson John M. D. , Dalrymple Kathryn V. , Wall Clare , Begum Shahina , Pallippadan Johny Jaijus , Cutfield Wayne S. , North Robyn , McCowan Lesley M. E. , Godfrey Keith M. , Mitchell Edwin A. , Poston Lucilla 
Published: February 2020

AbstractDietary patterns describe the combination of foods and beverages in a diet and the frequency of habitual consumption. Better understanding of childhood dietary patterns and antenatal influences could inform intervention strategies to prevent childhood obesity. We derived empirical dietary patterns in 1142 children (average age 6·0 (sd 0·2) years) in New Zealand, whose mothers had participated in the Screening for Pregnancy Endpoints (SCOPE) cohort study and explored associations with measures of body composition. Participants (Children of SCOPE) had their diet assessed by FFQ, and dietary patterns were extracted using factor analysis. Three distinct dietary patterns were identified: ‘Healthy’, ‘Traditional’ and ‘Junk’. Associations between dietary patterns and measures of childhood body composition (waist, hip, arm circumferences, BMI, bioelectrical impedance analysis-derived body fat % and sum of skinfold thicknesses (SST)) were assessed by linear regression, with adjustment for maternal influences. Children who had higher ‘Junk’ dietary pattern scores had 0·24 (sd 0·08; 95 % CI 0·04, 0·13) cm greater arm and 0·44 (sd 0·05; 95 % CI 0·01, 0·10) cm greater hip circumferences and 1·13 (sd 0·07; 95 % CI 0·03, 0·12) cm greater SST and were more likely to be obese (OR 1·74; 95 % CI 1·07, 2·82); those with higher ‘Healthy’ pattern scores were less likely to be obese (OR 0·62; 95 % CI 0·39, 1·00). In a large mother–child cohort, a dietary pattern characterised by high-sugar and -fat foods was associated with greater adiposity and obesity risk in children aged 6 years, while a ‘Healthy’ dietary pattern offered some protection against obesity. Targeting unhealthy dietary patterns could inform public health strategies to reduce the prevalence of childhood obesity.
Short-term determination and long-term evaluation of the dietary methionine requirement in adult dogs
Authors: Harrison Matthew , Thomas Gaelle , Gilham Matthew , Gray Kerry , Colyer Alison , Allaway David 
Published: February 2020

AbstractMethionine, an essential sulphur-containing amino acid (SAA), plays an integral role in many metabolic processes. Evidence for the methionine requirements of adult dogs is limited, and we employed the indicator amino acid oxidation (IAAO) method to estimate dietary methionine requirements in Labrador retrievers (n21). Using semi-purified diets, the mean requirement was 0·55 (95 % CI 0·41, 0·71) g/4184 kJ. In a subsequent parallel design study, three groups of adult Labrador retrievers (n52) were fed semi-purified diets with 0·55 g/4184 kJ (test diet 1), 0·71 g/4184 kJ (test diet 2) or 1·37 g/4184 kJ (control diet) of methionine for 32 weeks to assess the long-term consequences of feeding. The total SAA content (2·68 g/4184 kJ) was maintained through dietary supplementation of cystine. Plasma methionine did not decrease in test group and increased significantly on test diet 1 in weeks 8 and 16 compared with control. Reducing dietary methionine did not have a significant effect on whole blood, plasma or urinary taurine or plasma N-terminalproB-type natriuretic peptide. Significant effects in both test diets were observed for cholesterol, betaine and dimethylglycine. In conclusion, feeding methionine at the IAAO-estimated mean was sufficient to maintain plasma methionine over 32 weeks when total SAA was maintained. However, choline oxidation may have increased to support plasma methionine and have additional consequences for lipid metabolism. While the IAAO can be employed to assess essential amino acid requirements, such as methionine in the dog using semi-purified diets, further work is required to establish safe levels for commercial diet formats.
Effects of a high-DHA multi-nutrient supplement and exercise on mobility and cognition in older women (MOBILE): a randomised semi-blinded placebo-controlled study
Authors: Fairbairn Paul , Tsofliou Fotini , Johnson Andrew , Dyall Simon C. 
Published: February 2020

AbstractThere is a complex interplay between mobility and cognition in older adults. We have previously shown that a high-DHA multi-nutrient supplement improves habitual walking speed, verbal memory and psychomotor response latency in older women. Exercise also improves mobility and cognition in older adults, andn-3 fatty acids and exercise share a range of overlapping biological effects. This study examined for the first time the effects of the high-DHA multi-nutrient supplement and aerobic exercise on mobility and cognition in older women. Women (mean age 67 (sd8) years) were assigned to the following groups: multi-nutrient (1 g DHA, 160 mg EPA, 240 mgGinkgo biloba, 60 mg phosphatidylserine, 20 mgd-αtocopherol, 1 mg folic acid and 20 µg vitamin B12per d,n13), multi-nutrient and exercise (spin class twice per week,n14), exercise and placebo (n12) or placebo (n12). The multi-nutrient was given for 24 weeks and exercise for 12 weeks. No treatment effects were observed for the primary outcome, habitual walking speed. Improvements in verbal memory and executive function were seen for all treatments groupsv. placebo (all,P< 0·05). Significant improvements in self-reported emotional well-being were seen with multi-nutrient and exercise groupsv. placebo (P= 0·03). The results suggest that the high-DHA multi-nutrient supplement produces similar improvements in cognitive function to aerobic exercise, offering the intriguing prospect that supplementation may be able to mitigate some of the effects of low physical activity on cognitive function in the elderly.
Effects of mycoprotein on glycaemic control and energy intake in humans: a systematic review
Authors: Cherta-Murillo Anna , Lett Aaron M. , Frampton James , Chambers Edward S. , Finnigan Tim J. A. , Frost Gary S. 
Published: February 2020

AbstractMycoprotein is a food high in both dietary fibre and non-animal-derived protein. Global mycoprotein consumption is increasing, although its effect on human health has not yet been systematically reviewed. This study aims to systematically review the effects of mycoprotein on glycaemic control and energy intake in humans. A literature search of randomised controlled trials was performed in PubMed, Embase, Web of Science, Google Scholar and hand search. A total of twenty-one studies were identified of which only five studies, totalling 122 participants, met the inclusion criteria. All five studies were acute studies of which one reported outcomes on glycaemia and insulinaemia, two reported on energy intake and two reported on all of these outcomes. Data were extracted, and risk-of-bias assessment was then conducted. The results did not show a clear effect of acute mycoprotein on blood glucose levels, but it showed a decrease in insulin levels. Acute mycoprotein intake also showed to decrease energy intake at anad libitummeal and post-24 h in healthy lean, overweight and obese humans. In conclusion, the acute ingestion of mycoprotein reduces energy intake and insulinaemia, whereas its impact on glycaemia is currently unclear. However, evidence comes from a very limited number of heterogeneous studies. Further well-controlled studies are needed to elucidate the short- and long-term effects of mycoprotein intake on glycaemic control and energy intake, as well as the mechanisms underpinning these effects.
Recent increase of ulcerative lesions caused by Anisakis spp. in cetaceans from the north-east Atlantic
Authors: Pons-Bordas C. , Hazenberg A. , Hernandez-Gonzalez A. , Pool R.V. , Covelo P. , Sánchez-Hermosin P. , López A. , Saavedra C. , Fraija-Fernández N. , Fernández M. , Aznar F.J. 
Published: February 2020

Abstract
Species of Anisakis typically infect the stomach of cetaceans worldwide, often causing ulcerative lesions that may compromise the host's health. These nematodes also cause anisakiasis or allergic reactions in humans. To assess the risks of this emerging zoonosis, data on long-term changes in Anisakis infections in cetaceans are necessary. Here, we compare the prevalence and severity of ulcerative lesions caused by Anisakis spp. in five cetacean species stranded along the north-west Spanish coast in 2017–2018 with published data from 1991–1996. Open ulcers were found in 32/43 short-beaked common dolphins, Delphinus delphis; 3/5 striped dolphins, Stenella coeruleoalba; 1/7 bottlenose dolphins, Tursiops truncatus; and 1/3 harbour porpoises, Phocoena phocoena meridionalis; a single individual of long-finned pilot whale, Globicephala melas, was found uninfected. In common dolphins, the mean abundance of open ulcers per host was 1.1 (95% confidence interval: 0.8–1.3), with a maximum diameter (mean ± standard deviation) of 25.4 ± 16.9 mm. Stomachs with scars or extensive fibrosis putatively associated with Anisakis were detected in 14 and five animals, respectively. A molecular analysis based on the mitochondrial cytochrome c oxidase II gene using 18 worms from three cetacean species revealed single or mixed infections of Anisakis simplex sensu stricto and Anisakis pegreffii. Compared with the period 1991–1996, we found a strong increase of prevalence, abundance and extension of ulcerative lesions in most cetacean species. Anisakis populations could have increased in the study area over the last decades, although we cannot rule out that a higher environmental stress has also boosted the pathological effects of these parasites.
Ascaris lumbricoidesandAscaris suumvary in their larval burden in a mouse model
Authors: Deslyper G. , Sowemimo O.A. , Beresford J. , Holland C.V. 
Published: February 2020

AbstractAscariasis is a neglected tropical disease, caused byAscaris lumbricoides, affecting 800 million people worldwide. Studies focused on the early stage of parasite infection, occurring in the gut, liver and lungs, require the use of a mouse model. In these models, the porcine ascarid,Ascaris suum, is often used. The results obtained from these studies are then used to draw conclusions aboutA. lumbricoidesinfections in humans. In the present study, we sought to compare larval migration ofA. suumandA. lumbricoidesin mouse models. We used a previously developed mouse model of ascariasis, which consists of two mouse strains, where one mouse strain – C57BL/6J – is a model for relative susceptibility and the other – CBA/Ca – for relative resistance. Mice of both strains were infected with eitherA. suumorA. lumbricoides. The larval burden was assessed in two key organs, the liver and lungs, starting at 6 h post infection (p.i.) and ending on day 8 p.i. Additionally, we measured the larval size of each species (μm) at days 6, 7 and 8 p.i. in the lungs. We found that larval burden in the liver is significantly higher forA. lumbricoidesthan forA. suum. However, the inverse is true in the lungs. Additionally, our results showed a reduced larval size forA. lumbricoidescompared toA. suum.
Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America
Authors: Haider Najmul , Yavlinsky Alexei , Simons David , Osman Abdinasir Yusuf , Ntoumi Francine , Zumla Alimuddin , Kock Richard 
Published: February 2020

Abstract
Novel Coronavirus (2019-nCoV [SARS-COV-2]) was detected in humans during the last week of December 2019 at Wuhan city in China, and caused 24 554 cases in 27 countries and territories as of 5 February 2020. The objective of this study was to estimate the risk of transmission of 2019-nCoV through human passenger air flight from four major cities of China (Wuhan, Beijing, Shanghai and Guangzhou) to the passengers' destination countries. We extracted the weekly simulated passengers' end destination data for the period of 1–31 January 2020 from FLIRT, an online air travel dataset that uses information from 800 airlines to show the direct flight and passengers' end destination. We estimated a risk index of 2019-nCoV transmission based on the number of travellers to destination countries, weighted by the number of confirmed cases of the departed city reported by the World Health Organization (WHO). We ranked each country based on the risk index in four quantiles (4th quantile being the highest risk and 1st quantile being the lowest risk). During the period, 388 287 passengers were destined for 1297 airports in 168 countries or territories across the world. The risk index of 2019-nCoV among the countries had a very high correlation with the WHO-reported confirmed cases (0.97). According to our risk score classification, of the countries that reported at least one Coronavirus-infected pneumonia (COVID-19) case as of 5 February 2020, 24 countries were in the 4th quantile of the risk index, two in the 3rd quantile, one in the 2nd quantile and none in the 1st quantile. Outside China, countries with a higher risk of 2019-nCoV transmission are Thailand, Cambodia, Malaysia, Canada and the USA, all of which reported at least one case. In pan-Europe, UK, France, Russia, Germany and Italy; in North America, USA and Canada; in Oceania, Australia had high risk, all of them reported at least one case. In Africa and South America, the risk of transmission is very low with Ethiopia, South Africa, Egypt, Mauritius and Brazil showing a similar risk of transmission compared to the risk of any of the countries where at least one case is detected. The risk of transmission on 31 January 2020 was very high in neighbouring Asian countries, followed by Europe (UK, France, Russia and Germany), Oceania (Australia) and North America (USA and Canada). Increased public health response including early case recognition, isolation of identified case, contract tracing and targeted airport screening, public awareness and vigilance of health workers will help mitigate the force of further spread to naïve countries.
THE RACIAL HISTORY OF CRIMINAL JUSTICE IN AMERICA
Authors: Thompson Heather Ann 
Published: February 2020

AbstractThe United States today has the highest incarceration rate, as well as the largest number of people living under correctional control more broadly (including probation and parole), than any other country on the globe. The size of the American criminal justice system is not only internationally unparalleled, but it is also historically unprecedented. This apparatus is also deeply racialized. African Americans, Latinos, and indigenous populations (Hawaiian, Puerto Rican, Native American), are all represented in U. S. jails and prisons in numbers dramatically disproportionate to their representation in the population as a whole, and every non-White population is incarcerated at a rate far surpassing that of Whites. Notably, however, while the scale of today’s criminal justice system is unsurpassed and unprecedented, its severe racial disproportionality has always been a defining feature. Only by taking a close look at the long and deeply racialized history of the American criminal justice system, and more specifically at the regularly discriminatory application of the law as well as the consistent lack of equal justice under the law over time, can we fully understand not only why the American criminal justice system remains so unjust, but also why prison populations rose so dramatically when they did.