bluuebunny/crossref_metadata_2025_split huggingface dataset:
Delayed recurrence of acute subdural hematoma in a patient with plasminogen activator inhibitor mutation
Authors: Aljuboori Zaid , Nuru Mohammed , Schaber Alexandria , Nauta Haring , Sieg Emily 
Published: September 2020

Background:
Plasminogen activator inhibitor type I (PAI-1) is important for balancing the fibrinolytic effect of plasmin, and deficiency can result in increased risk of bleeding. We report a case of a patient with PAI-1 deficiency who presented with delayed spontaneous recurrence of an acute subdural hematoma (aSDH) after evacuation.

Case Description:
A 29-year-old male presented with altered mental status (AMS) after a fall at a construction site with Glasgow Coma Scale (GCS 4T). His coagulation profile was normal, and brain computed tomography (CT) showed a left-sided aSDH. He underwent emergent evacuation of the hematoma. On postoperative day 2, he was started on heparin for venous thromboembolism (VTE) prophylaxis. His neurological examination improved and was discharged with no focal deficits. Three days later, he presented with sudden AMS (GCS 7T); CT head showed a large hematoma at the site of original surgery. The hematoma was evacuated emergently. On readmission, the family informed providers that the patient had a history of PAI-1 deficiency. Postoperatively, only mechanical VTE prophylaxis was used and the patient was started on oral TXA per hematology recommendation. The patient improved and was discharged with no focal deficit. On follow-up, he remained neurologically stable.

Conclusion:
PAI-1 deficiency should be suspected in patients with delayed posttraumatic/surgical bleeding and a normal coagulation profile. If PAI-1 deficiency is evident or suspected, then a trial of antifibrinolytic agent should be used to treat and prevent recurrence of bleeding. Furthermore, chemical VTE prophylaxis should be avoided as it increases the risk for bleeding.
Foramen magnum osteochondroma causing myelopathy in a patient with hereditary multiple exostoses
Authors: Sinha Siddharth , Iyer Venkat , George K. Joshi 
Published: September 2020

Background:
Osteochondromas are commonly occurring benign bone tumors which may be either a solitary lesion or occur due to association with hereditary multiple exostoses (HMEs). There have been several reported cases of spinal osteochondromas, but intracranial lesions are rare.

Case Description:
A 51-year-old male with a history of multiple osteochondromas presented with myelopathy. He had an exostosis arising from the foramen magnum causing compression of the cervical spinal cord that was successfully removed. Genetic testing revealed that he had HMEs.

Conclusion:
Osteochondromas of the skull are extremely rare. However, parts of the foramen magnum ossify in cartilage and can give rise to an osteochondroma. Here, we present a patient with HMEs who developed cervical myelopathy due to an osteochondroma arising from the foramen magnum. Due to the cartilaginous ossification of the foramen magnum, clinicians should be aware that osteochondromas can occur in this location and potentially give rise to cervical myelopathy.
Evaluation of traction-chain properties of powerful tractors and combines complete with varieties of various performance
Authors: Kravchenko Vladimir Alekseevich , Kravchenko Lyudmila Vladimirovna , Melikov Izzet Melukovich 
Published: September 2020

The purpose of this study is to determine the traction and coupling properties of the undercarriage systems of wheeled mobile energy vehicles equipped with tires with different internal structures of the tire cover. It has been proved that the breaker ply rating for class 5 tractor should be equal to four, the carcass ply rating should be equal to six, the cord threads of the breaker and the carcass should have the slope of 70 and 0? respectively; the values of the corresponding tire parameters should be: 7, 6, 62, 15? for the propulsor of a combine. It has been established that when the undercarriage systems are equipped with experimental tires, the traction and coupling properties of mobile energy vehicles are improved.
PENGARUH EFEKTIVITAS KOMITE AUDIT, KUALITAS AUDIT DAN EFEKTIVITAS DEWAN DIREKSI TERHADAP MANAJEMEN LABA
Authors: Karina Ria , Sufiana Sufiana 
Published: September 2020

Penelitian ini bertujuan untuk menganalisis pengaruh efektivitas komite audit, kualitas audit, dan efektivitas dewan direksi terhadap praktik manajemen laba. Manajemen laba diukur dengan menggunakan nilai discretionary accrual. Variabel independen dalam penelitian ini adalah Komite Audit, Ukuran Komite Audit, Independensi Komite Audit, Keahlihan Komite Audit, Rapat Komite Audit, Skor Efektivitas Komite Audit, Reputasi Audit, Spesialisasi Audit, Masa Jabatan Audit, Ukuran Dewan Direksi, Independensi Dewan Direksi, Independensi Ketua Direksi, Rapat Dewan Direksi, Masa Jabatan CEO, Ukuran Perusahaan, Leverage, Oportunitas Pertumbuhan, Return on Asset, Konsentrasi Kepemilikan, dan Arus Kas Operasional.
Penelitian dilakukan pada perusahaan yang terdaftar di Bursa Efek Indonesia tahun 2013-2017. Metode pengambilan sampel menggunakan metode purposive sampling. Data penelitian diolah menggunakan aplikasi IBM SPSS.
Hasil penelitian menunjukkan bawah reputasi audit, masa jabatan audit, arus kas operasional memiliki pengaruh signifikan negatif terhadap manajemen laba. Sedangkan ukuran perusahaan, oportunitas pertumbuhan, dan ROA memiliki pengaruh signifikan positif terhadap manajemen laba sesuai dengan hipotesis penelitian. Variabel terkait komite audit dan karakteristik dewan direksi tidak mendukung hipotesis sehingga kedua jenis variabel tersebut dinilai tidak mampu berperan dalam mengurangi manajemen laba di Indonesia.
PENGARUH KOMPLEKSITAS OPERASI PERUSAHAAN DAN KOMITE AUDIT TERHADAP AUDIT DELAY DENGAN FINANCIAL DISTRESS SEBAGAI VARIABEL MODERASI PADA PERUSAHAAN PERTAMBANGAN YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2016 – 2018
Authors: Aulia Yoosita 
Published: September 2020

This study aims to analyze and prove financial distress is able to moderate the influence of the audit committee and audit committe on audit delay. The population in this study are mining companies listed on the Indonesia Stock Exchange for the period of 2016-2018. The sampling technique uses a purposive sampling technique with a total of 66 samples. The analysis technique used in this study is logistic regression. The results of this study indicate that . Financial distress does not moderate the effect of the complexity of the company's operations on audit delay on mining companies listed on the Indonesia Stock Exchange during the period 2016-2018. Financial distress does not moderate the effect of the audit committee on audit delay on mining companies listed on the Indonesia Stock Exchange during the period 2016-2018.
PENGARUH ECONOMIC VALUE ADDED DAN MARKET VALUE ADDED TERHADAP NILAI PERUSAHAAN PADA (PERUSAHAAN MANUFAKTUR SUB SEKTOR MAKANAN DAN MINUMAN YANG TERDAFTAR DI BEI TAHUN 2014-2018)
Authors: Mikrad Mikrad , Syukur Abdul 
Published: September 2020

The purpose of this study is to assess the extent to which the capital structure and profit of a company affect the value of a company and increase the prosperity of shareholders with a non-behavioral observation method of secondary data types entitled the influence of Economic Value Added and Market Value Added to the value of the company in the food and beverage sub sector registered on the Indonesia Stock Exchange in 2014-2018. For hypothesis testing using the F test, t test and coefficient of determination. T test is used to test hypotheses simultaneously, F test is used to test hypotheses partially, while the coefficient of determination is used to test how much the role of independent variables (EVA) and (MVA) together explain the changes that occur in the dependent variable (Company Value ). The analysis used is using multiple linear regression conducted through the program Eviews 9.0. Keywords: Economic Value Added, Market Value Added, and company value
INTEGRASI INTELLECTUAL CAPITAL DAN KNOWLEDGE MANAGEMENT SERTA DAMPAKNYA TERHADAP PENINGKATAN KINERJA PENJUALAN UKM KOTA TANGERANG
Authors: Humairoh Humairoh , Budi Agung 
Published: September 2020

Tujuan penelitian ini menguji pengaruh intellectual capital dan knowledge management terhadap peningkatan kinerja penjualan UKM di Kota Tangerang, Propinsi Banten. Sampel berjumlah 98 pelaku usaha UKM Kota Tangerang sebagai responden. Pengambilan sampel dengan menggunakan teknik purposive sampling dengan menggunakan instrumen kuesioner dengan skala likert 1-5. Penelitian ini menggunakan teknik path analysis dengan program Smart PLS. Hasil penelitian ini menunjukkan bahwa intellectual capital dan knowledge management berpengaruh positif dan signifikan terhadap peningkatan kinerja penjualan UKM. Peningkatan kinerja penjualan dapat dijelaskan oleh intellectual capital dan knowledge management sebesar 89,6%. Kata Kunci : Kinerja Penjualan, Inovasi Produk, Intellectual Capital, Knowledge Management
Meningkatkan Literasi Perbankan Syariah dengan mengembangkan aplikasi edukasi berbasis android
Authors: Anam Moh Khoirul , Abbas Dirvi Surya , Anggraini Lia 
Published: September 2020

Total pangsa pasar perbankan syariah masih di bawah 5% dari total market share perbankan nasional. Salah satu penyebabnya adalah konsumen atau masyarakat masih kurangnya pengetahuan, pemahaman dan loyalitas konsumen yang masih rendah terhadap bank syariah. Penelitian ini mengembangkan aplikasi edukasi berbasis android dan menguji efektifitas aplikasi tersebut pada peningkatan pengetahuan karyawan Yayasan Baitul Yataama Fadlan tentang perbankan syariah. Responden menggunakan aplikasi edukasi dan mempelajari konten perbankan syariah selama 2 hari. Sebelum dan sesudah responden menggunakan aplikasi tersebut dilaksanakan survey dengan memberikan berbagai pertanyaan. Survey bertujuan untuk melihat pengetahuan responden sebelum dan sesudah penggunaan aplikasi, apakah terdapat kenaikan yang signifikan. Hasil survey pertama menggunakan kuesioner menunjukkan hasil sebesar 47%. Survey kedua menunjukkan hasil sebesar 67%. Terdapat kenaikan prosentase responden yang menjawab mengetahui perbankan syariah sebesar 20%. Hal ini dapat disimpulkan bahwa Aplikasi edukasi perbankan syariah berpengaruh signifikan dalam meningkatkan pengetahuan responden
Penerapan Metode Brainstorming Berbantu Alat Peraga terhadap Kemampuan Komunikasi Matematis Peserta Didik
Authors: Jusra Hella , Rahmadiana Syifa , Wahidin Wahidin 
Published: September 2020

ABSTRAK
Penelitian bertujuan untuk menelaah dan menghasilkan kajian tentangimplementasi metode Brainstorming berbantu alat peraga matematika terhadap kemampuan komunikasi matematis peserta didik. Metode penelitian yang digunakan adalah quasi experimental dengansampel yang diteliti sebanyak 72 peserta didik tingkat SMP secara random. Penelitian ini terdiri dari dua kelas, yaitu kelas eksperimen dan kelas kontrol. Dalam penelitian ini teknik pengumpulan data menggunakan instrumen kemampuan komunikasi matematis berbentuk uraian. Teknik analisis data dengan menggunakan uji-t setelah dilakukan uji prasyarat. Berdasarkan hasil penelitian didapatkan rata-rata kemampuan komunikasi matematis peserta didik yang diajar menggunakan metode Brainstormingerbantu alat peraga lebih tinggi dibandingkan dengan yang tidak diajar menggunakan metode Brainstorming berbantu alat peraga. Hal ini dapat disimpulkan bahwa metode pembelajaran Brainstormingberbantu alat peraga dapat meningkatkan kemampuan komunikasi matematis peserta didik dengan kriteria sedang.
Kata kunci:metode Brainstorming, alat peraga, kemampuan komunikasi matematis.

ABSTRACT
Thestudy aims to determine whether or not there is an implementation of theBrainstorming method assisted aid teaching to the students’mathematical communication ability. Thesample of this research are 72 students. The research used data collection method by using instrument test of mathematical communication ability in the form ofdescription. Data analysis techniques using t-test after the prerequisite test. Based on the results of the study it was found that the average of mathematical communication ability of students taught using the Brainstorming methodassisted props were higher than those not taught using the Brainstorming methodassisted props. It can be concluded that theBrainstorming method assisted props can improve mathematical communication ability of students with medium criteria.
Keywords: Brainstorming method, aid teaching, mathematics communication ability.
Quantifying the utility of a multidisciplinary neuro-oncology tumor board
Authors: Khalafallah Adham M. , Jimenez Adrian E. , Romo Carlos G. , Kamson David Olayinka , Kleinberg Lawrence , Weingart Jon , Brem Henry , Grossman Stuart A. , Mukherjee Debraj 
Published: September 2020

OBJECTIVE
There has been limited research on the efficacy of multidisciplinary tumor boards (MDTBs) in improving the treatment of patients with tumors affecting the nervous system. The objective of the present study was to quantify the utility of MDTBs in providing alternative diagnostic interpretations and treatment plans for this patient population.

METHODS
The authors performed a prospective study of patients in 4 hospitals whose cases were discussed at MDTBs between July and November 2019. Patient demographic data, diagnoses, treatment plans, and eligibility for clinical trials were recorded, among other variables.

RESULTS
A total of 176 cases met eligibility criteria for study inclusion. The majority (53%) of patients were male, and the mean patient age was 52 years. The most frequent diagnosis was glioblastoma (32.4%). Among the evaluable cases, MDTBs led to 38 (21.6%) changes in image interpretation and 103 (58.2%) changes in patient management. Additionally, patients whose cases were discussed at MDTBs had significantly shorter referral times than patients whose cases were not discussed (p = 0.024).

CONCLUSIONS
MDTB discussions led to significant numbers of diagnostic and treatment plan changes as well as shortened referral times, highlighting the potential clinical impact of multidisciplinary care for patients with nervous system tumors.
Development and validation of a clinical prediction score for poor postoperative pain control following elective spine surgery
Authors: Yang Michael M. H. , Riva-Cambrin Jay , Cunningham Jonathan , Jetté Nathalie , Sajobi Tolulope T. , Soroceanu Alex , Lewkonia Peter , Jacobs W. Bradley , Casha Steven 
Published: September 2020

OBJECTIVEThirty percent to sixty-four percent of patients experience poorly controlled pain following spine surgery, leading to patient dissatisfaction and poor outcomes. Identification of at-risk patients before surgery could facilitate patient education and personalized clinical care pathways to improve postoperative pain management. Accordingly, the aim of this study was to develop and internally validate a prediction score for poorly controlled postoperative pain in patients undergoing elective spine surgery.METHODSA retrospective cohort study was performed in adult patients (≥ 18 years old) consecutively enrolled in the Canadian Spine Outcomes and Research Network registry. All patients underwent elective cervical or thoracolumbar spine surgery and were admitted to the hospital. Poorly controlled postoperative pain was defined as a mean numeric rating scale score for pain at rest of > 4 during the first 24 hours after surgery. Univariable analysis followed by multivariable logistic regression on 25 candidate variables, selected through a systematic review and expert consensus, was used to develop a prediction model using a random 70% sample of the data. The model was transformed into an eight-tier risk-based score that was further simplified into the three-tier Calgary Postoperative Pain After Spine Surgery (CAPPS) score to maximize clinical utility. The CAPPS score was validated using the remaining 30% of the data.RESULTSOverall, 57% of 1300 spine surgery patients experienced poorly controlled pain during the first 24 hours after surgery. Seven significant variables associated with poor pain control were incorporated into a prediction model: younger age, female sex, preoperative daily use of opioid medication, higher preoperative neck or back pain intensity, higher Patient Health Questionnaire–9 depression score, surgery involving ≥ 3 motion segments, and fusion surgery. Notably, minimally invasive surgery, body mass index, and revision surgery were not associated with poorly controlled pain. The model was discriminative (C-statistic 0.74, 95% CI 0.71–0.77) and calibrated (Hosmer-Lemeshow goodness-of-fit, p = 0.99) at predicting the outcome. Low-, high-, and extreme-risk groups stratified using the CAPPS score had 32%, 63%, and 85% predicted probability of experiencing poorly controlled pain, respectively, which was mirrored closely by the observed incidence of 37%, 62%, and 81% in the validation cohort.CONCLUSIONSInadequate pain control is common after spine surgery. The internally validated CAPPS score based on 7 easily acquired variables accurately predicted the probability of experiencing poorly controlled pain after spine surgery.
Human motor endplate remodeling after traumatic nerve injury
Authors: Gupta Ranjan , Chan Justin P. , Uong Jennifer , Palispis Winnie A. , Wright David J. , Shah Sameer B. , Ward Samuel R. , Lee Thay Q. , Steward Oswald 
Published: September 2020

OBJECTIVE
Current management of traumatic peripheral nerve injuries is variable with operative decisions based on assumptions that irreversible degeneration of the human motor endplate (MEP) follows prolonged denervation and precludes reinnervation. However, the mechanism and time course of MEP changes after human peripheral nerve injury have not been investigated. Consequently, there are no objective measures by which to determine the probability of spontaneous recovery and the optimal timing of surgical intervention. To improve guidance for such decisions, the aim of this study was to characterize morphological changes at the human MEP following traumatic nerve injury.

METHODS
A prospective cohort (here analyzed retrospectively) of 18 patients with traumatic brachial plexus and axillary nerve injuries underwent biopsy of denervated muscles from the upper extremity from 3 days to 6 years after injury. Muscle specimens were processed for H & E staining and immunohistochemistry, with visualization via confocal and two-photon excitation microscopy.

RESULTS
Immunohistochemical analysis demonstrated varying degrees of fragmentation and acetylcholine receptor dispersion in denervated muscles. Comparison of denervated muscles at different times postinjury revealed progressively increasing degeneration. Linear regression analysis of 3D reconstructions revealed significant linear decreases in MEP volume (R = −0.92, R2 = 0.85, p = 0.001) and surface area (R = −0.75, R2 = 0.56, p = 0.032) as deltoid muscle denervation time increased. Surprisingly, innervated and structurally intact MEPs persisted in denervated muscle specimens from multiple patients 6 or more months after nerve injury, including 2 patients who had presented > 3 years after nerve injury.

CONCLUSIONS
This study details novel and critically important data about the morphology and temporal sequence of events involved in human MEP degradation after traumatic nerve injuries. Surprisingly, human MEPs not only persisted, but also retained their structures beyond the assumed 6-month window for therapeutic surgical intervention based on previous clinical studies. Preoperative muscle biopsy in patients being considered for nerve transfer may be a useful prognostic tool to determine MEP viability in denervated muscle, with surviving MEPs also being targets for adjuvant therapy.
АЛЬТЕРНАТИВНИЙ ПІДХІД ДО ПРОВЕДЕННЯ ПРАКТИЧНОЇ СКЛАДОВОЇ НАВЧАЛЬНОЇ ДИСЦИПЛІНИ «АВТОМОБІЛЬНА ТЕХНІКА В ТОМУ ЧИСЛІ АВТОМОБІЛЬНА ПІДГОТОВКА»
Authors: КУЗЬМЕНКО Руслан , ДУФАНЕЦЬ Ігор , ЗЕЛЕНЮХ Олександр , КОВБА Микола 
Published: September 2020

Розглянуто можливості запровадження змін в організації вивчення практичної складової навчальної дисципліни «Автомобільна техніка в тому числі автомобільна підготовка» з врахуванням рівня підготовки слухачів, в факультативний спосіб.
Розкрито структуру навчального курсу, яка складається з теоретичної та практичної компоненти з визначенням компонентів які є обов’язковими для допуску до виконання практичних завдань. Вивчення теоретичної частини проходить під час проведення групових занять, подальше закріплення матеріалу під час самостійної роботи. Теоретична частина включає вивчення будови та експлуатації автомобіля, правил дорожнього руху, основ законодавства, охорони праці та навколишнього середовища, основ безпечного керування та безпеки дорожнього руху, правил надання першої допомоги при ДТП, професійної етики водія та культури водіння. Система дистанційного навчання Moodle, яка запроваджена в навчальний процес Національної академії сухопутних військ забезпечує більш ефективне вивчення теоретичного матеріалу.
Заняття з практичного водіння проводяться під керівництвом інструктора в складі 2-х осіб. Вправи водіння відпрацьовуються спочатку на майданчику, далі на дорогах з малою та великою інтенсивністю руху. Після засвоєння навчального матеріалу слухачі здають іспит, в разі успішної здачі якого отримують свідоцтво державного зразка. Серед слухачів, які навчаються, вже є особи з посвідченням водія. Що призводить до повторного вивчення ними навчального матеріалу, що є недоречним. Одним з шляхів вирішення такої ситуації є винесення частини навчального матеріалу за тіло навчальної дисципліни та проведення її у факультативний спосіб з врахуванням індивідуальних особливостей та здібностей до навчання слухачів. Проведено розрахунки існуючої схеми підготовки та моделювання альтернативної схеми вивчення навчальної дисципліни.
Запровадження такого підходу дасть можливість ефективніше організовувати вивчення навчальної дисципліни та економити матеріальні засоби.
АВТОБІОГРАФІЧНІ МАТЕРІАЛИ: РЕТРОСПЕКТИВНА ХАРАКТЕРИСТИКА
Authors: РОЗМАН Ірина 
Published: September 2020

У статті розглядаються питання дослідження педагогічних особистостей шляхом аналізу документальної біографії, біографічного дослідження художньої літератури, спогадів, мемуарів. Наголошено на тому, що у науково-дослідницькій діяльності вчені постійно стикаються з усіма суттєвими відтінками терміну «особистість», тоді як їм доводиться використовувати фактичний опис і теоретично оцінювати, тобто розміщувати життя особи та її творчість у певному історико-соціальному контексті та у сучасних реаліях.
З’ясовано, якщо біографічні дослідження та роботи є переконливими, достовірними, фактично та інформаційно всебічними, то вони однаковою мірою стосуються як наукової (професійної), так і частково художньої біографії, індивідуального контенту особистості. Закцентована увага на професію, характер, диспозицію, продуктивність, ментальний і внутрішній світ людини. Висвітлені наукові надбання відомих педагогів та педагогічних діячів. Зосереджена увага на необхідності виокремити аспекті особливості місця, яке займають автобіографічні матеріали та меморіальні спогади знаних педагогів для розкриття їх значення для розвитку історії педагогіки. Розкрито значення праці Русової «Мої спомини», Олександра Барвінського «Спомини з мого життя», М. Драгоманова «Австро-руські спомини (1867–1877)», А.Макаренка «Мої педагогічні погляди», Ступариа к Б. «З порога вічності». На тлі аналізу розкриваються чинники світоглядного формування особистості, родинного і соціокультурного середовища, суспільної думки та зміст, етапи, напрями, інші аспекти їх наукової, організаційно-педагогічної, культурно-просвітницької, державницької діяльності. Наголошено на те, що через призму особистих контактів спогади проливають світло на життєдіяльність визначних діячів, педагогів, просвітян, інтелектуалів.