bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Health Canada Surveillance Tool could be an effective method for assessing alignment with 2019 Canada's Food Guide
Authors: Mulligan Christine , Franco-Arellano Beatriz , L'Abbe Mary R 
Published: June 2020

AbstractThe Health Canada Surveillance Tool (HCST), a Canadian nutrient profile (NP) model, assesses products’ adherence to the 2007 Canada's Food Guide (CFG), using thresholds for total fat, saturated fat, sugars and sodium. In 2019, new dietary guidelines were published (i.e., CFG 2019); however; the HCST has not been updated to reflect changes implemented in this new guide. Given suggestions to adapt previously validated NP models rather than create new models, this research aimed to assess whether the HCST could be a useful tool to assess alignment with updated dietary guidance. Specifically, the objective of this study was to test the agreement between products’ alignment with the CFG 2007 (as per the HCST) and products’ alignment with the recently released CFG 2019 guidelines. This study analyzed data from the University of Toronto Food Label Information Program (FLIP) 2017 database. FLIP contains label and nutrition information for prepackaged food products from top Canadian grocery retailers. Products were categorized into Tiers based on HCST thresholds: Tiers 1 and 2 were considered “in line” with dietary guidance, while Tiers 3, 4 and “Other” (i.e. foods not addressed by CFG) were considered “not in line”. Two raters independently classified foods according to their alignment to CFG 2019. Proportions of products that were considered “in line” with CFG 2007 and 2019 were calculated. Overall agreement between alignment with CFG 2007 and 2019 was determined by cross-classifications of the proportion of products considered “in line” or “not in line” with both CFG versions. Cohen's Kappa (κ) statistic tested the level of agreement (Interpretation of κ: 0.01–0.20, “slight”; 0.21–0.40, “fair”; 0.41–0.60, “moderate”; 0.61–0.80, “substantial”; and 0.81–0.99, “almost perfect”). Analyses were conducted overall and by Health Canada's Table of Reference Amounts for Food category. In total, n = 16,973 products were analyzed, with 98% inter-rater reliability for CFG 2019 alignment. Overall, 30.2% and 28.2% of products were “in line” with CFG 2007 and 2019, respectively, with 80.4% overall agreement and “moderate” kappa agreement (κ [95% CI]: 0.49 [0.46, 0.49]). Overall agreement in individual food categories ranged from 100% (Dessert Toppings, Sauces, Sugars and Sweets; κ: N/A) to 54.8% (Eggs, κ: 0.21 [-0.01, 0.4]). From these results, the HCST appears to be an effective NP model for assessing alignment with CFG 2019. Further analysis could elucidate specific areas for adaptation of the HCST to optimize its functionality in this context.
Association between mental health and nutritional status in university students aged 18–24 years
Authors: Wilson Hannah , Amirabdollahian Farzad , Farhat Grace , Macdonald-Clarke Claire 
Published: June 2020

AbstractIt is estimated that 19% of 16–24 year olds suffer from a mental health condition. There has been a fivefold increase in reported mental health problems from first year university students since 2006/07(1). Limited but consistent evidence suggests that nutritional status is linked to mental health. University students may be more vulnerable to the impact of diet on mental health due to increased food insecurity and risk of stress. The aim of this project was to determine the association between nutritional status and stress, anxiety and depression in university students.After obtaining ethical approval, university students (n = 562) aged 18–24 y were recruited. A cross-sectional design was used to measure body mass index (BMI), percent body fat (%BF), capillary blood measures of glucose and lipids and nutrient intake by validated 3-day food diary. Mental health status was determined by DASS21 questionnaire (2) and participants were grouped into 5 categories: normal, mild, moderate, severe and extremely severe for anxiety, depression or stress. Difference in nutritional status between categories was determined by a Kruskal-Wallis test and Dun-Bonferroni post-hoc tests using SPSS version 25 and significance determined as p < 0.05.Results showed that depression was associated with %BF (p = 0.025), blood glucose (p < 0.001), dietary protein (p = 0.003) and dietary sugar (p = 0.041). Anxiety was associated with blood glucose (p < 0.001) and dietary protein (p = 0.007).Stress was associated with total cholesterol (p = 0.007), HDL cholesterol (p = 0.007) and blood glucose (p < 0.001).In light of these findings, further research is required to investigate the effect of student lifestyle habits and university practices on mental health and nutritional status so that strategic interventions can be designed to improve the health of young adults at university.
Physical activity: the earlier the better. Bones awareness
Authors: Altaba Iris Iglesia , Santos Pilar Ferrer , Miguel-Berges María Luisa , Barrantes Paloma Flores , Villagrasa Pilar Samper , Martínez Gerardo Rodríguez 
Published: June 2020

IntroductionThere is scarce research on bone health in early stages due to the difficulties in accessing to bone health assessment methods in absence of pathology conditions. Consequently, there is no much information on the determinants of bone health. The aim of this study is to elucidate the association of moderate-vigorous physical activity (MVPA) and bone mineral density of children from Aragon accounting for socioeconomic, role parental modelling, dietary and sedentary behavior effects.Material & MethodsThe longitudinal cohort ‘Growth and Feeding during Lactation and Early Childhood in Children of Aragon (CALINA in Spanish)’ included 1,629 born children from Aragon (Spain) in 2009. From those, after 7 years, 339 children (176 boys and 163 girls) were assessed. Bone mineral density (BMD) using Dual X-ray absorciometry (–DXA-), diet quality index (DQI) using a food frequency questionnaire(-FFQ-), sedentary behaviors by questionnaire, and physical activity (using accelerometry-actigraph 3GTX-) were evaluated, as well as if they were or not rapid weight gainers during the first year of life.ResultsFrom the 339 children, 116 boys (66.5%) and 63 girls (38.7%) met the current MVPA recommendations of at least? 1 hour/day. Boys meeting MVPA recommendations did a mean of 84.02 minutes of MVPA per day and had a BMD of 0.60 g/cm2, while those not meeting the recommendations, did a mean of 43.91 minutes of MVPA and had a BMD of 0.59 g/cm2. Girls meeting MVPA recommendation did 75.52 minutes and had a BMD of 0.59 g/cm2, and those not meeting, did 42.81 minutes of MVPA and had a BMD of 0.58. Models, include BMI z-score (age/sex adjusted based in Anthro standards from WHO), weekly sedentary time, DQI, BMI of the mother and whether or not they had been rapid weight gainers from 0–12months as confounders and were performed for BMD having MVPA as a predictor. A significant association was found only for boys between MVPA and BMD (β = 0.145, p-value = 0.02) while no association was found for girls (β = 0.06, p-value = 0.40).DiscussionThere is still an important physical activity gap between boys and girls. In boys, physical activity is positively associated with BMD, whereas in girls, no significant associations seem to exist. More research is required to elucidated the effects of lifestyle behaviors on bone health in children.
Does protein supplementation impact appetite and energy intake in older adults? A systematic review
Authors: Ben-Harchache Sana , Horner Katy 
Published: June 2020

AbstractProtein supplementation represents an attractive strategy to prevent skeletal muscle mass loss and function with aging. However, it could be counterproductive in older adults, due to adverse effects on appetite and energy intake (EI). Understanding the effects of protein supplementation on appetite and energy intake is therefore key when investigating the potential efficacy for use in improving health outcomes. This systematic review aimed to assess the literature investigating the effects of protein supplementation on energy intake, and/or appetite in healthy older adults.PubMed and The Cochrane Library, as well as MEDLINE, CINAHL, EBSCO, and Web of Science databases were searched up to 21 March 2019 for published studies and theses. The review was limited to randomized controlled trials and longitudinal studies in healthy adults over 60 years of age that reported effects of protein supplementation compared to control or pre-intervention on appetite and/or energy intake. The review was conducted according to PRISMA guidelines.Out of 5,429 articles screened, 90 full-texts were reviewed and twenty-six studies (11 acute, 15 longitudinal) included. Studies involved a total of 1439 participants (502 male, 881 females). Of the acute studies, 3 reported conditions in which appetite was suppressed, 5 studies reported no effect and one study reported a condition in which appetite ratings increased following a protein load versus control. Three studies reported conditions in which ad libitum test meal EI was suppressed following protein preload and 7 reported no difference. When examining total EI (accounting for protein supplement and test meal), 2 studies reported no difference and 8 reported conditions where total EI was increased with protein supplement compared to control. Longitudinal studies ranged from 2–26 weeks duration. Two studies reported effects on appetite, one showing hunger to be suppressed on higher (1.0g/kg/d) compared to lower protein diet, and another showing hunger in response to whey consumption increased, but fullness also increased.14 studies reported effects on EI, most commonly assessed by food diary, and all showed no effect of increased protein intake compared to control on daily EI.The systematic review indicates that while appetite may be suppressed under some conditions, the current literature supports protein supplementation in older adults, as it either has a positive effect or no effect on total EI in both short and longer-term studies. Therefore, protein supplementation may represent an effective solution to address protein deficiencies in older adults without compromising daily EI.
Comparison of Portuguese and Turkish older adults’ nutritional status assessed by MNA-FF
Authors: Oliveira Bruno M. P. M. , Öztürk Meryem Elif , Poínhos Rui , Afonso Cláudia , Yabancı Ayhan Nurcan , Vaz de Almeida Maria Daniel 
Published: June 2020

AbstractMalnutrition is associated to a progressive decline in health, reduced physical and cognitive functional status and mortality. However, the malnutrition prevalence differs across countries. Previous studies reported 19% of malnourished elderly in Turkey and 1.3% in Portugal.We aimed to compare the nutritional status between between Portuguese and Turkish older adults using the Mini-Nutritional Assessment.This is a cross-sectional study using data from the Pronutrisenior project, collected in Vila Nova de Gaia, Portugal (n = 430), and a study in Ankara, Turkey (n = 162). The sample consisted of older adults living at their homes. Socio-demographic data, clinical data from the medical records, the full form of Mini-Nutrititional Assessment, MNA-FF and anthropometry (weight, height, BMI, mid-arm circumference and calf circumference) were collected.Turkish older adults lived more frequently with children, are more likely to be widow/widower, and have a higher probability of being housewife/househusband. A larger proportion of the Portuguese have tooth loss, diabetes, hypertension, oncologic diseases, kidney diseases, osteoarticular problems, or eye problems and a larger proportion of the Turkish have anemia. The BMI average is smaller in the Turkish sample, while the calf circumference average is larger. Turkish have a larger proportion of malnourished or at risk of malnutrition (4.9% and 31.5% vs. 1.2% and 24.0%, respectively). The average MNA-FF score is higher among the Portuguese, males and on people using denture, and without: toothloss, hypertension, CVD, anemia and oncological diseases. Moreover, higher MNA-FF scores were associated with younger ages, higher BMI and higher calf circumference.The effect size was larger for CVD and sex.The prevalence of malnutrition in European and American populations ranges from 1% to 15% in ambulatory living elders, more common among females as in this work. Other studies showed that higher BMI is related with lower malnutrition prevalence and higher prevalence of obesity-related chronic diseases. Tooth loss was more frequent in the Portuguese, which may be due to a higher intake of sweets or packaged food. Portuguese elders had lower calf circumferences but higher BMI, which may be related to lower muscle mass and/or higher fat mass. The differences between the Portuguese and the Turkish may be related to the different per capita gross national product, positively correlated with BMI and the consumption of processed foods. Anemia in Turkish elders may be related with BMI and their lower consumption of meat and the higher tea intake that may reduce iron absorption, as reported by other studies.
Examining Nutrient Intakes and Academic Performance in Young Irish Twins
Authors: Bennett Grace , Bermingham Kate , Scully Helena , O'Sullivan Aifric 
Published: June 2020

AbstractIntroduction:Appropriate nutrition is vital for growth and cognitive development in childhood. Vitamin D, omega 3, zinc, iodine, and iron are important micronutrients for neurodevelopment(1). National survey data suggest that children in Ireland are not meeting recommended intakes of these key nutrients(2). The aim of this research was to determine mean daily intakes of vitamin D, omega 3, zinc, iodine, and iron among school-aged children and examine the relationship between intakes and academic performance.Materials and Methods:Anthropometric and dietary data was collected from pairs of twins. Four-day food diaries were used by parents to record all food, drinks and supplements consumed. Diaries were entered into the analytical software, Nutritics, which provided the nutrient content of foods consumed. Academic performance was assessed using an online questionnaire. Teachers were asked to rank the child's performance in reading, writing, maths and overall performance using a 5-point likert scale, which was then categorised into “Average” and “Above Average”. SPSS V24 was used for statistical analysis.Results:Data was collected from 51 pairs of twins aged 8–10 years, and 60% of participants were female. Mean nutrient intakes were as follows; vitamin D = 2.34μg (SD = 1.71), omega-3 = 0.68 g (SD = 0.43), zinc = 7.93 mg (SD = 3.56), iodine = 140.82μg (SD = 59.26) and iron = 9.76 mg (SD = 3.050). All children met recommendations for iodine compared to iron (61%), zinc (52%) omega-3 (15%), and vitamin D (11%). Supplements contributed to 68% and 25% of vitamin D and omega 3 intakes. Meat was the largest contributor to zinc and iron. Milk contributed to ~80% of iodine intakes. Intra-twin correlations indicated a strong familial effect on nutrient intakes. Children who were ranked “above average” in all categories had significantly higher zinc and iodine intakes compared to average students.Discussion:The findings of this study concurred with previous analysis of nutrient intakes of Irish and UK children. Animal source foods including meat and milk contributed a high proportion to intakes of key nutrients. Children ranked above average in school had higher nutrient intakes. Public health initiatives should emphasise the importance of key nutrients related to cognitive development and subsequent academic outcomes.
“The boob answers a lot of problems”: Exploring barriers and enablers to successful extended breastfeeding in women with high BMIs
Authors: O'Reilly Sharleen , O'Brien Eileen , Walker Hannah , O'Carroll Eimear , Courtney Joanne , McAuliffe Fionnuala 
Published: June 2020

AbstractIntroduction:Breastfeeding provides optimal nutrition for infants yet breastfeeding rates worldwide do not meet WHO targets for 50% exclusive breastfeeding at 6 months. Ireland's breastfeeding rate is one of the lowest in the world (only 58% initiation) and maternal obesity and overweight is prevalent (> 50% pregnancies). Women with obesity and overweight are particularly at risk of having lower breastfeeding rates but little is known about the factors that supported this sub-group to successfully breastfeed. Our aim was to explore barriers and enablers present in: women with high body mass index (BMI) who successfully breastfed for > 6 months, partners of women with > 6 months breastfeeding, and healthcare professionals (HPs) who support women to breastfeed.Materials and Methods:Women with high BMIs (n = 20) were recruited via an extended breastfeeding Facebook group and snowballing. Partners (n = 20) were recruited via social media and word of mouth. HPs (n = 19) were recruited via posters and direct invitation. Semi-structured interviews were conducted either in-person or on telephone and digitally recorded. Interviews were verbatim transcribed and thematically analysed. Two research students independently coded each interview and consensus decided any discrepancies.Results:Barriers to breastfeeding identified aligned with previous research but the challenges appear to be increased for either the frequency or intensity of occurrence in women with high BMIs. Common barriers are: a lack of breastfeeding culture; limited access within health services to high quality and consistent breastfeeding advice; large breast size; and issues with breastfeeding in public. Enablers for successful extended breastfeeding are: strong self-efficacy; supportive partner and family; social networks for creating breastfeeding-friendly settings; seeking support from a lactation consultant; and breastfeeding aides (clothing, pillows, lanolin, etc.).Discussion:Women with high BMIs are able to successfully breastfeed for extended periods of time when they are provided with the right support at the right time and in a way that is acceptable to them and their families. Reorientation of maternity health services to ensure greater and more consistent support for women with high BMIs to initiate breastfeeding is needed. HPs engaging with women with high BMIs should seek to support them through the use of the enablers identified and make a conscious decision to include appropriate advice for women with high BMIs in their antenatal education and any postpartum services provided.
Kinetics and mechanism of α-glucosidase inhibition by edible brown algae in the management of type 2 diabetes
Authors: Attjioui Maha , Ryan Sinead , Ristic Aleksandra Konic , Higgins Thomas , Goni Oscar , Gibney Eileen , Tierney Joanna , O'Connell Shane 
Published: June 2020

AbstractPrevalence of type 2 diabetes mellitus has significantly increased in the last three decades and currently affects about 1 in 10 globally. A common therapeutic target for type 2 diabetes is α- glucosidase, an essential enzyme located at the brush border of the small intestinal epithelium. The inhibition of α-glucosidase results in a reduced digestion of carbohydrates and a decrease of postprandial blood glucose. Although, synthetic inhibitors are available in the market, these are usually associated with significant gastrointestinal side effects. In this study, natural inhibitors derived from edible brown algae are being investigated as an alternative.Polysaccharide- and polyphenolic-enriched extracts from Ascophyllum nodosum and Fucus vesiculosus were characterized and screened for their inhibitory effects against α-glucosidase obtained from rat intestine using maltose, sucrose, and p-nitrophenyl (pNPG) as substrates. Acarbose was used as a synthetic inhibitor. Furthermore, enzyme kinetics and mechanism of inhibition of α- glucosidase were determined using linear and non-linear regression methods (GraphPad Prism ver. 6, GraphPad Software, La Jolla California USA).All tested extracts showed a dose-dependent inhibitory effect against α-glucosidase. However, the type of inhibition varied between the extracts. Most importantly, the composition analysis showed that the seaweed extracts had different polysaccharide and phenolic contents, suggesting different mode of actions against α-glucosidase. The relation between chemical composition and inhibitory activity of the compounds are discussed.In summary, the current study demonstrates the mechanisms in which different brown seaweed extracts with various composition effectively inhibit α-glucosidase. Therefore, this natural inhibitor can be considered as a potential candidate for the management of type 2 diabetes mellitus.
Yerba mate improves cardiovascular health in normocholesterolemic and hypercholesterolemic subjects
Authors: Sarria Beatriz , Martinez-Lopez Sara , Garcia-Cordero Joaquin , Gonzalez-Ramila Susana , Mateos Raquel , Bravo Laura 
Published: June 2020

AbstractYerba mate is highly consumed in South America and has become a popular beverage worldwide because of its healthy properties: antioxidant, vaso-dilating, lipid-reducing, anti-glycation, anti-inflammatory and weight-reducing effects, among others. These effects have been attributed to its high content in polyphenols, mainly chlorogenic acidS, but also quercetin, kaempferol and rutin. Other components in mate are methylxhantines, saponins, vitamins, minerals and alkaloids.The objective of this work was to evaluate the effects of regularly consuming a moderate, realistic amount of yerba mate (3 beverages/day) on cardiovascular health and anthropometric parameters, in healthy and cardiovascular risk subjects.A randomized, crossover, controlled study was performed in normocholesterolemic (NC, n = 25) and hypercholesterolemic (HC, n = 27), non-smoker, non-vegetarian, men and women, with BMI 18–25 kg/m2. After a run-in stage, the effects of consuming three servings/day of mate during 8 weeks (mate stage) were compared with an isotonic drink during the same time (control stage). Along the study, polyphenol rich foods were restricted. At the beginning and the end of each intervention, blood pressure was measured, urine and blood samples were collected. Triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very-low-density lipoprotein (VLDL) cholesterol concentrations were measured. Dietary records and physical activity questionnaires were completed in each stage. Results were statistically studied using a mix model with repeated measures and Bonferroni test (SPSS 23.0).The regular consumption of yerba mate decreased blood lipid concentrations [TC (p < 0.001), LDL (p = 0.001), TG (p = 0.027)] and blood pressure [systolic (p < 0.001), diastolic (< 0.001)] in both groups, with greater effects in HC than NC. Thus, it may be concluded that moderate consumption of yerba mate reduces cardiovascular risk, particularly in hypercholesterolemic subjects.Funded by the Spanish State Research Agency, projects AGL2010-18269 and AGL2015-69986-R