bluuebunny/crossref_metadata_2025_split huggingface dataset:
Students' awareness of breast cancer risk factors (results of a sociological study)
Authors: Kryvoviaz O. V. , Shcherba I. K. , Tomashevska Yu. O. , Kudria V. V. 
Published: January 2020

The organization of services and measures aiming to improve prevention, diagnosis and treatment of women who suffer from cancer of reproductive organs remains a pressing issue which has to be addressed at the state level. The rates of breast cancer incidence and mortality in Ukraine are respectively 45% and 56% higher in comparison to the European countries. Each fourth woman is diagnosed with breast cancer at stage 3 or 4, when the effectiveness of treatment is greatly reduced. Early detection of the disease increases the chances for successful treatment in 98.1% of cases.
The aim of the work was to determine the extent of awareness of the breast cancer (BC) prevention methods among the female students as well as to reveal any risk groups for this disease.
The survey material consisted of 240 completed questionnaires. They included thirteen questions about the existence of risk groups and developmental factors, the presence of breast cancer among the relatives of respondents, the methodology of breast self-examination and breast cancer prevention measures. The study used sociological and medical-statistical methods.
The results of the survey reveal the majority of the respondents are aware of the risk for developing breast cancer, only 10.4% marked all the responses about the risk factors for breast cancer, 56.7% believe that they are not at risk of developing breast cancer. Most of the respondents are familiar with the method of breast self-examination. However, only every third respondent does it regularly. About half of the interviewed students visit their gynecologist regularly. Moreover, it will facilitate the process of filling in information gaps regarding breast cancer and methods for its detection, make girls change their attitude to this matter and encourage them to take more responsibility for their own health.
The results of the study show the insufficient awareness level regarding the risk factors causing breast cancer development as well as the low level of caution regarding the possibility of development of this type of cancer.
Furthermore, the present study emphasized the necessity to introduce into the education process the so called «educational» questionnaires, which would not only help find out the extent of students’ awareness of a certain topic but also expand their knowledge of this topic.
Thermogravimetric investigation of a new intranasal gel with noopept
Authors: Burlaka B. S. , Belenichev I. F. , Gladyshev V. V. 
Published: January 2020

Recently, in the world, there is a negative dynamics of increasing diseases of the central nervous system. Creation of neuropeptide-based dosage forms with high pharmacological activity, neuroavailability and improved biopharmaceutical properties is an urgent problem today. The development of a novel intranasal dosage form with noopept that has high neuroavailability and therapeutic efficacy deserves attention. The purpose of the work is to conduct thermogravimetric studies to substantiate the possibility of combining active and auxiliary substances in a new intranasal gel with noopept and to characterize its temperature mode of manufacture.
The following were used as objects of thermogravimetric studies: separate nasal gel ingredients: noopept (CAS No. 157115-85-0, obtained from Shijiazhuang Prosperity Import and Export Co., Ltd., China. Purity: ≥ 98%), Bischofite Poltava (standardized solution at ZDMU medicine technology department), polysorbate-80 (obtained from Sinbias LLC in Kyiv), sodium CMC (obtained from Sinbias LLC in Kyiv), glycerol (obtained from Sinbias LLC in Kyiv), benzalkonium chloride (obtained from LLC East-plus in Zaporizhzhya), as well as a ready-made intranasal gel without noopept, and a gel with noopept. Thermographic analysis was performed on a Shimadzu DTG-60 (Japan) derivative with a platinum-platinum thermocouple while heating specimens in aluminum crucibles (15 to 250 °C). As the reference substance used α-Al2O3. The heating rate was 10 ºC per minute. The weight of the samples was from 19.22 mg to 57.21 mg.
As a result of thermogravimetric studies of the active and auxiliary substances of intranasal gel with noopept it is found that the technological process of making a gel with noopept is advisable to take into account thermolabile compounds, namely, a preservative, it is advisable to enter the formulation at a temperature not higher than 40 ºC. It has been found that the developed formulation of noopept gel is a mixture of active and auxiliary substances, the ingredients of which do not interact and can be combined in one dosage form.
Polymorphism E23K KCNJ11 Gen as a Risk Factor of Diabetes Mellitus in Serawai Tribe Of Bengkulu
Authors: Sunita Raden , Sahidan Sahidan , Hidayat Rachmat , Meinisasti Resva 
Published: January 2020

ABSTRACT

Background: Type 2 diabetes mellitus (T2DM) is a multifactorial disease involving genetic and environmental factors. The E23K KCNJ11 gene polymorphism causes KATP canal overactivity, decreases cell membrane depolarization potential, and decreases insulin secretion. E23K polymorphism of the KCNJ11 gene as a risk factor for T2DM.
Research Objective: This study aimed to analyze the E23K polymorphism of the KCNJ11 gene as a risk factor for T2DM in the Bengkulu Serawai.
Method: This study is a case-control study. The subjects of the study were 100 people with T2DM patients as a case group (50 people) and Non-DM subjects with families who did not have a history of T2DM as a control group (50 people). Fasting blood glucose (GDP) was analyzed by spectrophotometry and E23K KCNJ11 gene by polymerase chain reaction fragment length polymorphism (PCR-RFLP). Data were analyzed by statistics.
Results: The frequency of AA genotypes in cases was higher than the controls (12% and 8%) (p = 0.001). The frequency of A allele in the case was higher than the control (32% and 18%) (p = 0.017). The risk of T2DM on AA / GA genotypes was 4.75 times higher in cases than controls (p = 0,000, OR 4.75 95% CI 2.01-11.24). The risk of T2DM in A allele was 2.14 times higher in cases than in controls (p = 0.017, OR 2.14, 95% CI 1.11-4.15).
Conclusion: E23K polymorphism of the KCNJ11 gene as a risk factor for T2DM in Bengkulu Serawai Tribe.

Keywords: E23K gene KCNJ11, DMT2, Non-DMT2.
Papaya (Carica Papaya L.) Seed Extract as Male Contraception via Decreasing The Quality of Rat's (Rattus Norvegicus) Sperm
Authors: Nita Sri , Setiawan Arum , Inggarsih Rara , Tantri Uci , Hardiana Meryska 
Published: January 2020

Background. Population growth needs to be controlled so as not to cause new and serious problems. Pregnancy and birth control is a solution to control this sizable population growth. Contraception is a way to prevent pregnancy, by inhibiting the process of ovulation, fertilization and implantation. Nevertheless, most of contraceptive regiments were aimed to woman. Male contraception nowadays is very rare. Papaya seed is one of the male contraceptive candidates which has the potential to be developed as male contraception. Previous studies have shown the potential of papaya seed extract could reduce the weight of reproductive organs of male white rats, where it was believed that there was a decrease in spermatogenesis activity.
Methods. This research was an in-vivo experimental research post-test only with control group. The study used 32 male and healthy rats (Rattus norvegicus) Wistar strain with 8-10 weeks of age. Rats were grouped into 1 control group and 4 treatment groups that were randomly selected. The four treatment groups were group 1: control administered 1% 2ml CMC orally one time per day every morning, group 2: were given N-hexane papaya seed fraction, group 3: were given ethyl acetate papaya seed fraction and group 4: were given ethanol-water papaya seed fraction. The three fractions were given to rats orally at a dose of 100 mg / KgBB / day for 24 days. After that, rat's testes and epidydimis were evacuated to observe reproductive organs and sperm quality.
Results. Anatomically, Group 2 and 3 were statistically significant in reducing testicular's and epidydimis' weight compared to the control group, but the n-hexane group was more effective in reducing testicular weight than other treatment groups. Furthermore, groups 2, 3 and 4 were statistically significant in reducing sperm quality (motility, viability, amount of sperm cells and normal sperm cell morphology) compared to the control group, but the n-hexane group was more effective in reducing sperm quality than other treatment groups.
Conclusion. Papaya seed n-hexane fraction has potential as a male contraceptive by reducing spermatogenesis activity and decreasing sperm quality in white rats.
Keyword : papaya seed, male contraception, rat's sperm
KLASIFIKASI KONTEN POST PADA MEDIA SOSIAL INSTAGRAM PERGURUAN TINGGI XYZ MENGGUNAKAN ALGORITMA NAIVE BAYES
Authors: Agustina Nova , Cahyanto Andrian , Herwanto Joko , Ratnasari Ratih , Dewi Sintia 
Published: January 2020

Media sosial memiliki peran penting sebagai alat komunikasi untuk berbagi informasi dan saling terhubung. media sosial digunakan sebagai ruang untuk berinteraksi dengan orang berbagai kalangan. Salah satu media sosial yang paling banyak digunakan di dunia, termasuk di Indonesia adalah Instagram. Penelitian ini bertujuan untuk mencari tahu konten post yang bagaimana yang paling optimal dalam Online Engagement. Penelitian ini menggunakan data post yang diunggah oleh akun Instagram Perguruan Tinggi XYZ pada 22 September 2015 hingga 4 Juni 2019. Post yang dianalisis dalam penelitian ini berjumlah 426 konten post. Uji banding dilakukan untuk melihat perbedaan online engagement antara konten post. Hasil dari penelitian ini menunjukkan bahwa tipe post dan waktu posting (bulan dan hari) memiliki pengaruh signifikan terhadap online engagement (like dan komentar). Sedangkan bulan yang memiliki pengaruh paling signifikan terhadap like dan komentar adalah bulan Maret, Juni, dan Juli. Hari Kamis, Jumat, dan Sabtu merupakan hari yang memiliki pengaruh signifikan terhadap like dan komentar.
Analysis of the chemical safety state in the Luhansk region in the conditions of the warning conflict
Authors: Тарасов В.Ю. , Захарова O.І. , Заіка Р.Г. , Захарова А.І. 
Published: January 2020

The statistics of emergency situations in Ukraine for 2018 are analyzed. The total cost of damage caused by emergencies amounted to more than UAH 516 million. About 15% of the territory of Ukraine with a population of more than 10 million people is in a critical ecological state, in fact not favorable for living. It is shown that the most environmentally hazardous production (coke and metallurgical plants, power plants and chemical industry enterprises) are concentrated in the Donetsk and Luhansk oblasts. The production complex consists of 3995 enterprises, 7 of which are environmentally hazardous objects. Damage to technological installations can result in dangerous consequences for the population and the environment near the enterprises. Due to emergency emissions and discharges there is pollution of atmospheric air, surface and underground waters and soils. Storage tanks and sludges, storage sites for industrial waste, such as slag dumps, waste heaps, stocks of raw materials, etc. located on the territories of tailings storage facilities also cause environmental hazards. There is also the risk of contamination of the area outside the conflict zone and the Sea of Azov in the event of pollution of the Siversky Donets, Kalmius, Mius and Mokryy Yelanchyk rivers, which occur near the clash line and in areas beyond the control of the Government of Ukraine.
As a result of the analysis of the state of chemical safety in Ukraine, the example of PrJSC «Severodonetsk Azot Association» shows the need to increase safety requirements and prepare new qualified personnel for radiation, chemical and biological protection.
The necessity of attracting additional funds for ensuring the effectiveness of the actions of the territorial subsystems of the EGS GZ in the region in the conditions of emergencies, enhancing the readiness of the specialized fire fighting service of the city's civil protection to the actions for appointment, ensuring the timeliness and quality of carrying out work to save people, extinguishing fires, eliminating the consequences of emergencies , creation of the possibility of conducting search, rescue, restoration and friend services around the clock their urgent work.
Diagnóstico de actividades didácticas en el aprendizaje del idioma en los niños de educación básica.
Authors: Sandra Paulina Porras Pumalema , Miguel Patricio Bravo Yépez , Lara Velarde Adriana Carolina 
Published: January 2020

El objetivo de la presente investigación, fue realizar un diagnóstico de actividades didácticas en el aprendizaje del idioma de los niños de educación básica sexto y séptimo grado de la Escuela García Moreno del barrio del Batán de la ciudad de Riobamba. Para ello, se aplicó un conjunto de actividades didácticas orientadas a la evaluación de las destrezas de listening, reading speaking y writing del idioma inglés, tales como: organizadores, mentefactos, formulación de oraciones, actividades de sugestión, diálogos, etc. La investigación fue enfocada sobre la aplicación de un proceso pedagógico en el aprendizaje de inglés, siendo de tipo descriptiva, bibliográfica de campo y explicativa aplicada en una población y muestra de 5 docentes y 44 estudiantes con similar nivel de conocimientos del idioma inglés. Para la recolección de datos se utilizaron las técnicas de las encuestas y el test. La información recolectada fue tabulada y representada mediante tablas y gráficos estadísticos para luego analizarla e interpretarla. Los resultados permitieron establecer que la diversificación de las actividades permitió motivar a los estudiantes en las competencias comunicacionales. Así también sirve como una línea base del proceso pedagógico del desarrollado del aprendizaje del idioma inglés para la aplicación de propuestas, mediante estrategias orientadas a definir incidencias o mejoras.
Diseño de un proceso de producción de ácido cítrico por simulación computacional.
Authors: Guadalupe Alcoser María Augusta , Parada Rivera Mabel Mariela , Flores Fiallos Linda Mariuxi , Manobanda Pinto Paúl Marcelo 
Published: January 2020

El diseño de un proceso de producción de ácido cítrico a partir de la fermentación con Aspergillus Niger por simulación computacional, se realizó con el uso del software SuperPro Designer, los parámetros de diseño se establecieron en base a estudios previos, mismos que se ingresaron a la plataforma de cálculo, posteriormente los resultados obtenidos en el diseño se analizaron técnica y económicamente, lo que permitió determinar una cantidad de producción de ácido cítrico de 6 914. 69 ton/año, al usar precios FOB (Free on board) se tiene una inversión total de $ 31 460 000 junto a un VAN (Valor actual neto) de $165 000 y un TIR (Tasa interna de retorno) del 8.05%, lo que indica que el proyecto se puede llevar a cabo y resulta rentable en un tiempo de retribución de 8 años. El proceso consta de dos etapas: fermentación y aislamiento, que deben realizarse bajo las condiciones de operación (T= 25ºC y P= 1 atmósfera en la mayoría de las operaciones) y las condiciones óptimas de fermentación para el Aspergillus niger (T= 35ºC, pH= 5.8 y P= 1 atmósfera) que son adecuadas para obtener un producto de calidad que pueda ofertarse en el mercado nacional como internacional. Finalmente, se comprueba que el uso de software permite desarrollar estudios técnicos sin la necesidad de recurrir a largos períodos de tiempo con análisis experimentales en laboratorio, es decir, nos ahorra: tiempo, costos de pre-diseño y errores.
Response of Soil Applied Herbicides at Different Application Timings on The Weed Control Efficacy and Phytotoxicity to Rice In Dry-seeded Condition
Authors: Ahmed Sharif , Hossain Akbar , Miajy Abu Abdullah , Awan Tahir H 
Published: January 2020

Dry-seeded rice (DSR) is a labor and water saving emerging production system. The use of pre-emergence herbicides was found to be the most effective weeds control measure under the DSR system. Although several herbicides are now available in market, the selection of right herbicides with a time of application is crucial for effective control of weeds as well as to reduce the phyto toxicity of crops. A field study in a split-plot design with three replications was conducted to evaluate the effect of application time of soil applied herbicides (viz., 3 times - before crop sowing, after crop sowing but before the first irrigation, and after sowing and first irrigation) and four weeding regimes (viz., weed free, partial-weedy, herbicide oxadiargyl 80 g ai ha-1, and pendimethalin 1000 g ai ha-1) on weed control efficacy, crop performance as well as phytotoxicity of applied herbicides under DSR system. Rice plant stand establishment was highly influenced by application time of herbicides and weeding regimes. Application of pendimethalin at 1000 g ai ha-1 significantly reduced the density of rice plant, more so as sowing was advanced. Compared with the non-treated (partial-weedy) treatment (190 to 195 rice plants m-2), pendimethalin application before sowing, after sowing but before irrigation, and after sowing and irrigation reduced rice plant density by 48, 25 and 12%, respectively. While no significant difference was observed on plant density due to the application of oxadiargyl 80 g ai ha-1, regardless of application time. In case of weed control efficacy for individual herbicides, pendimethalin effectively controlled weeds even spraying before sowing and irrigation; but comparatively less effective than spraying after irrigation. In controlling weeds, oxadiargyl was only effective when spraying after sowing and irrigation, but not before irrigation. Grain yield was significantly increased as the time of herbicide was delayed from before sowing (2.2-2.4 t ha-1), after sowing but before irrigation (2.5-2.6 t ha-1), and after sowing and irrigation (4.0-4.1 tha-1). The results suggest that pre-emergence herbicides should be applied after sowing and irrigation for controlling weeds effectively and also reduce crop toxicity under the DSR system.
Bangladesh Agron. J. 2019, 22(1): 15-25
Influence of Green Manuring Crops on Dry Matter Production and Soil Health Improvement
Authors: Irin IJ , Biswas PK , Ullah MJ , Roy TS , Khan MA 
Published: January 2020

The field experiment was conducted at the Agronomy farm of Sher-e-Bangla Agricultural University to evaluate the impact of different kind of green manures on soil nutrient balance through adding biomass and N,P and K accumulation. Green manuring crops were incorporated after in situ cultivation and results showed that, the biomass incorporation increased the N production in soil. The biomass from Sesbania rostrata, Sesbania aculeata and Crotalaria juncea gave the higher dry matter and nutrient status. Incorporation of Sesbania rostrata and Sesbania aculeata added more organic matter and nitrogen to the soil after green manure incorporation than the prior soil. However, the improved soil quality was recorded with S. rostrata and S. aculeata followed by C. juncea and V. unguiculata incorporation as compared to control (no green manure) and other green manuring crops. The nutrient balance of soil after incorporation of different green manuring crops specially S. rostrata, S. aculeata and C. juncea showed positive balance of nutrients than other green manures.
Bangladesh Agron. J. 2019, 22(1): 39-45
Fertilizer Recommendation for Four Crop Based Cropping Pattern: Potato- Boro- T. Aus-T. Aman Under AEZ – 11
Authors: Barman A , Shome S , Alam MJ , Akhtar S , Hossain MA 
Published: January 2020

A field experiment on Potato-Boro-T. Aus-T. Aman cropping pattern was conducted in the High Ganges Floodplain Soil of Jashore (AEZ - 11) during 2014-2015 and 2015-2016 to find out optimum fertilizer management for intensive cropping attern, in relation to soil health.There were eight different treatments viz. T1=100% NPKSZnB (STB= Soil Test Based), T2=T1 + 25% N, T3=T1 + 25% NP, T4=T1 + 25% NK, T5=T1 + 25% PK, T6=T1 + 25% NPK, T7=75% of T1, and T8=Native fertility (control) as individual crop management. The experiment was laid out in randomized complete block design with three replications. Results revealed that the tuber yield of potato, grain yields of boro, T. Aus and T. Aman were significantly influenced by the fertilizer treatments. The maximum tuber yield (25.70 and 24.80 t ha-1), grain yields of boro (6.50 and 6.31 t ha-1), T. Aus (3.13 and 3.10 t ha-1) and T. Aman (3.95 and 3.98 t ha-1) was obtained from the T6 treatment where 25% additional NPK was added with 100% STB in both the year. These yields weretatistically similar with that produced by all other fertilizer treatments except the native fertility treatment. Highest rice equivalent yield (REY) of 12.63 t ha-1 was obtained from T6 treatment whereas lowest REY of 5.93 t ha-1 was obtained from control.
Bangladesh Agron. J. 2019, 22(1): 71-78
Effect of Nutrient Management on Growth and Yield of Cauliflower Hybrids in haor area
Authors: Salwa M , Kashem MA 
Published: January 2020

The experiment was conducted in the Dekarhaor of Noagaon village under South Sunamganj Upazila of Sunamganj district during November 2017 to February 2018 to observe the effect of nutrients management on growth and yield of cauliflower hybrids. Two Hybrids namely ShiraGiku (V1) and Rupali (V2), and four combinations of nutrients, viz. (i) recommended rate of N-P-K-S-Zn-B @ 180-80-180-28-4.5-2.1 kg ha-1(F1), (ii) F1 + 25% N-P-K- S-Zn-B of F1 (F2), (iii) F1 – 25% N-P-K-S-Zn-B of F1 (F3), and (iv) cow dung @ 10 t ha-1 (F4) was conducted in a factorial randomized complete block design (RCBD) and replicated thrice. Plant height (cm), numbers of leaves plant-1, leaf length (cm) and leaf breadth (cm), and spreading diameter (cm) were collected at 15 days intervals, while the yield data were recorded at harvest. The parameters were significantly varied due to hybrids and fertilizers packages. Higher gross yield (42.52tha-1) was found in Shira Giku and lower (42.12 t ha-1) from Rupali. Higher curd yield of 25.17 t ha-1 was obtained in Shira Giku than Rupali (9.61 t ha-1). The highest gross yield of 44.45 t ha-1 was obtained when the crop was treated with cowdung @ 10 t ha-1 followed by recommended fertilizer rate (F1). The curd yield of 18.19 t ha-1 was obtained with 25% less than recommended fertilizer rate of application (F3). The highest gross yield of 52.93 t ha-1 was obtained in V1F1 combination and the lowest of 30.10t ha-1in V2 F1. Results revealed that the Hybrid ShiraGiku with recommended dose of fertilizer (180-80-180-28-4.5-2.1 kg ha-1N-P-K-S-Zn-B) performed the best in comparison to other treatment combinations.
Bangladesh Agron. J. 2019, 22(1): 95-104