bluuebunny/crossref_metadata_2025_split huggingface dataset:
SARS-CoV-2 as a Factor to Disbalance the Renin–Angiotensin System: A Suspect in the Case of Exacerbated IL-6 Production
Authors: Franco Rafael , Rivas-Santisteban Rafael , Serrano-Marín Joan , Rodríguez-Pérez Ana I. , Labandeira-García José L. , Navarro Gemma 
Published: July 2020

AbstractFever in infections correlates with inflammation, macrophage infiltration into the affected organ, macrophage activation, and release of cytokines involved in immune response, hematopoiesis, and homeostatic processes. Angiotensin-converting enzyme 2 (ACE2) is the canonical cell surface receptor for SARS-CoV-2. ACE2 together with angiotensin receptor types 1 and 2 and ACE2 are components of the renin–angiotensin system (RAS). Exacerbated production of cytokines, mainly IL-6, points to macrophages as key to understand differential COVID-19 severity. SARS-CoV-2 may modulate macrophage-mediated inflammation events by altering the balance between angiotensin II, which activates angiotensin receptor types 1 and 2, and angiotensin 1–7 and alamandine, which activate MAS proto-oncogene and MAS-related D receptors, respectively. In addition to macrophages, lung cells express RAS components; also, some lung cells are able to produce IL-6. Addressing how SARS-CoV-2 unbalances RAS functionality via ACE2 will help design therapies to attenuate a COVID-19–related cytokine storm.
Augustine’s Theological Method And Contribution To The Christian Theology
Authors: Objantoro Enggar 
Published: July 2020

Today, the world is influenced by many views, such as secularism and atheism, which affect many people, so they are far from God. Because of them, moral and ethical standards are not based on the belief of God, but just on the humanity standard. For Christianity, the views cause many of God's believers to leave the Scripture's truths. To solve the problem, Christians must learn from the Christian theologian who has a significant contribution to Christian theology. One of the Christian theologians is Augustine. Augustine was one of Christian’s famous theologians, in which his theology/thoughts are influenced Christian theology today. This research uses a library research method to explore Augustine's ideas. The books that expose about Augustine's views are used to find Augustine's theology. The result of the research is that Augustine's theology is necessary and relevant to Christian's theology today to confront the world's views so that the people of God do not live far from God.
SISTEM PENDUKUNG KEPUTUSAN PENGUKUR KINERJA KARYAWAN PADA RUMAH MAKAN WONG SOLO KEDIRI MENGGUNAKAN METODE TOPSIS
Authors: Saharlan Ellita , Suryawan Muhaji Bayu 
Published: July 2020

Saat ini rumah makan Wong Solo masih menggunakan cara manual untuk mengetahui kelompok karyawan yang berprestasi dan kurang kompeten, maka dari itu dibuatlah sebuah penelitian yang berjudul “Sistem Pendukung Keputusan Pengukur Kenierja Karyawan pada Rumah Makan Wong Solo Kediri Menggunakan Metode TOPSIS (Technique For Other Reference by Similarity Ideal Solution), Tujuan penelitian ini adalah mampu mengimplementasikan metode TOPSIS dalam sistem pendukung keputusan untuk mengukur kinerja karyawan dan mampu membangun sistem pendukung keputusan yang membantu mengukur kinerja Karyawan Wong Solo.Metode penelitian ini menggunakan beberapa tahapan yaitu: menyusun perencanaan, melaksanakan tindakan, melaksanakan pengamatan, melakukan refleksi. Adapun sumber data diperoleh dari observasi, wawancara, dan study Literature. Kemudian Landasan teori yang akan digunakan dalam sistem pendukung keputusan penilai kinerja karyawan rumah makan Wong Solo dengan Metode TOPSIS.Berdasarkan analisa data yang dilakukan, diperoleh kesimpulan bahwa Metode TOPSIS dapat diterapkan ke dalam sistem pendukung keputusan pengukur kinerja karyawan yang digunakan sebagai rekomendasi HRD rumah makan Wong Solo Kediri untuk menentukan karyawan terbaik dan terburuk. Perhitungan menggunakan Metode ini sesuai dengan perhitugan manual. Diharapkan dengan adanya sistem ini, pihak Rumah Makan Wong Solo khususnya HRD dapat mengukur kinerja karyawan dengan lebih efisien dan cepat dari pada dengan cara manual.
SISTEM INFORMASI EKSPEDISI PENGIRIMAN PAKET DAN DOKUMEN BERBASIS WEB MENGGUNAKAN PHP DAN MYSQL PADA PT. KERTA GAYA PUSAKA
Authors: Wijayanti Nike , Abijono Heri 
Published: July 2020

Tugas akhir ini merancang sistem tracking ekspedisi pada Kerta Gaya Pusaka yang bermanfaat untuk pengguna, agar dapat menawarkan dan menyebarkan informasi yang baik dengan mudah dan cepat serta dapat memberikan inspirasi kepada pembaca untuk mengetahui informasi ekspedisi termudah. Pembuatan sistem tracking dilakukan dengan menggunakan pemrograman website sehingga memudahkan pengguna dalam mendapatkan informasi. Metode penelitian yang digunakan berdasarkan informasi secara langsung dan akurat, sehingga dapat memperoleh sasaran yang tepat bagi pengguna. Perancangan sistem menggunakan bahasa pemrograman PHP dan database MySQL yang dipublikasikan dari hosting online sebagai editor dan domain berbayar sebagai alamat website. Hasil yang diharapkan dapat diperoleh secara tepat sasaran bagi pengguna. Sehingga website ekspedisi menjadi salah satu praktik terbaik dalam pengembangan ilmu
Sistem Pendukung Keputusan Seleksi Atlet Panahan menggunakan Logic Fuzzy metode AHP-TOPSIS
Authors: Praningki Tutus , Bayu Muhaji , Pramono Agus 
Published: July 2020

Panahan adalah cabang olahraga di induk organisasi PERPANI. Pelatihan yang dibentuk guna mencitakan atlet panaha terbaik dalam perkembangannya selalu berudaha mengikuti kejuaraan dengan langkah pelatihan atlet panahan secara teratur. Proses seleksi atlet pada PERPANI dinilai masih manual dan belum terperinci. Dalam penilaian yang bersifat subjektif (berdasarkan kepentingan pribadi), dapat menimbulkan kecemburuan pada proses penyeleksian seorang atlet. Diperlukan sebuah sistem guna membantu solusi tersebut, sistem dengan Logic Fuzzy metode AHP-TOPSIS dipilih untuk menyeleksi atlet panahan. Penulis menggunakan 6 kriteria dan 24 subkriteria dalam sistem. Proses penentuan bobot kriteria menggunakan Logic Fuzzy pada perhitungannya. Penelitian ini menggunakan Bahasa perograman PHP dan menggunakan MySQL sebagai basisdatanya. Penelitian ini berhasil memberikan hasil sistem pendukung keputusan menggunakan Logic Fuzzy metode AHP-TOPSIS mampu mengatasi permasalah dalam melakukan seleksi atlet panahan. Kata Kunci: MySQL, Seleksi Atlet Panahan, PHP, Logic Fuzzy, AHP-TOPSIS
Hydrological evaluation of open-access precipitation data using SWAT at multiple temporal and spatial scales
Authors: Pang Jianzhuang , Zhang Huilan , Xu Quanxi , Wang Yujie , Wang Yunqi , Zhang Ouyang , Hao Jiaxin 
Published: July 2020

Abstract. Temporal and spatial precipitation information is key to
conducting effective hydrological-process simulation and forecasting.
Herein, we implemented a comprehensive evaluation of three selected
precipitation products in the Jialing River watershed (JRW) located in
southwestern China. A number of indices were used to statistically analyze the
differences between two open-access precipitation products (OPPs), i.e.,
Climate Hazards Group InfraRed Precipitation with Station (CHIRPS) and
Climate Prediction Center Gauge-Based Analysis of Global Daily Precipitation (CPC), and the rain gauge (Gauge). The three products were then
categorized into subbasins to drive SWAT simulations. The results show the following. (1) The three products are highly consistent in temporal variation on a monthly
scale yet distinct on a daily scale. CHIRPS is characterized by
an overestimation of light rain, underestimation of heavy rain, and high
probability of false alarm. CPC generally underestimates rainfall of all
magnitudes. (2) Both OPPs satisfactorily reproduce the stream discharges at
the JRW outlet with slightly worse performance than the Gauge model. Model
with CHIRPS as inputs performed slightly better in both model simulation and
fairly better in uncertainty analysis than that of CPC. On a temporal scale,
the OPPs are inferior with respect to capturing flood peak yet superior at
describing other hydrograph features, e.g., rising and falling processes and
baseflow. On a spatial scale, CHIRPS offers the advantage of deriving
smooth, distributed precipitation and runoff due to its high resolution. (3) The water balance components derived from SWAT models with equal simulated
streamflow discharges are remarkably different between the three
precipitation inputs. The precipitation spatial pattern results in an
increasing surface flow trend from upstream to downstream. The results of
this study demonstrate that with similar performance in simulating
watershed runoff, the three precipitation datasets tend to conceal the
identified dissimilarities through hydrological-model parameter calibration,
which leads to different directions of hydrologic processes. As such,
multiple-objective calibration is recommended for large and spatially resolved
watersheds in future work. The main findings of this research suggest that
the features of OPPs facilitate the widespread use of CHIRPS in extreme
flood events and CPC in extreme drought analyses in future climate.
Identificación de recursos turísticos potenciales importantes por criterios de singularidad identitaria y universal. El municipio de Ugíjar en la Comarca de las Alpujarras
Authors: Fernández Quero Juan Luis , Navarro Valverde Francisco Antonio 
Published: July 2020

La promoción de las áreas rurales es una cuestión primordial para luchar contra su despoblamiento. Actualmente existen deficiencias en la percepción del valor de los recursos propios existentes en muchos de estos territorios. Situación debida a factores como la falta de cultura territorial, profundización local y difusión investigadora de aquellos que pudieran poseer ciertas singularidades o aspectos de interés a diferentes escalas. La salvaguardia de la identidad territorial posibilita una evasión ante los procesos banalizadores conservando a su vez la riqueza patrimonial.
The promotion of rural areas is a key issue to fight against their depopulation. Currently there are deficiencies in the perception of the value of own resources in many of these territories. Situation due to factors such as lack of territorial culture, local deepening and research dissemination of those which may have certain singularities or aspects of interest at different scales. The safeguarding of territorial identity makes possible an evasion before the banalizing processes while conserving the patrimonial wealth.
Assessment of Anxiety in Healthcare Providers Working in ICU during COVID-19 Pandemics
Authors: Dal Hakan , Keklik Esra Sultan Karabulut , Kaki Baris 
Published: July 2020

Objective: After onset of coronavirus disease (COVID-19), the risk for exposure or having the disease is increased among healthcare providers involved in the treatment of the disease. There are reports of healthcare providers died due to COVID-19 disease who became ill during work. This resulted in psychological distress in healthcare providers. In this study, we aimed to investigate anxiety in healthcare providers working at intensive care units, considered as an area at highest risk, and to confirm social psychological factors among healthcare providers working in hospitals.
Materials and Methods: The study included 106 healthcare providers working in intensive care unit who accepted participation to the survey. The healthcare providers responded to survey were stratified into 2 groups as those working in pandemic intensive care unit (pandemic group; n=55) and those working in remaining intensive care units (others; n=51). The relationship between sociodemographic characteristics and levels of anxiety and depression was evaluated using State-Trait Anxiety Inventory.
Results: In our study, it was found that STAI anxiety scores were higher in healthcare providers working in pandemic intensive care unit during COVID-19 outbreak (p<0.05). In the pandemic group, anxiety scores were significantly higher in male healthcare providers when compared to female healthcare providers (p>0.05). However, it was seen that healthcare providers with work experience of 1-10 years had higher mean anxiety level in STAI-II scale. It was also seen that anxiety score was significantly higher in those with work experience of 1-10 years when compared to those work experience of 11-20 years or ≥21 years (p<0.05). Work setting, male gender, experience of intensive care and concerns about outbreak were identified as factors associated to anxiety.
Conclusion: Our study showed that STAI anxiety scores were higher in healthcare providers working in pandemic ICU during COVID-19 outbreak. The COVID-19 period has led psychological problems in healthcare providers working in ICU. It is important to provide psychological support and information, and to monitor psychological status in healthcare providers.
Boswellia serrata Derived Phytochemicals against Dysentery
Authors: Rout Krutanjali , Naik Chinmayee , Prusty Sujata , Panigrahi G. K. , Swain Sitaram , Bhattacharyay Dipankar 
Published: July 2020

Dysentery is an intestinal inflammation, primarily of the colon. Nature is a major source of medicines for different diseases like Dysentery. Phytochemicals from Boswellia serrata plant extract can cure Dysentery. This objective of the study is to identify the phytochemical of Boswellia serrata capable of curing Dysentery. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectively deactivate the enzyme, thereby interrupting the life cycle of the organism.
Trigonella foenum-graecum Derived Phytochemicals against Cellulitis
Authors: Tripathy Bidyashree , Jal Soumya , Bhattacharyay Dipankar 
Published: July 2020

Cellulitis is a common and sometimes painful bacterial skin infection. Trigonella foenum-graecum extract is traditionally used to cure diseases like cellulitis. Phytochemicals from Trigonella foenum-graecum plant extract can cure Cellulitis. The objective of the study is to identify the phytochemical of Trigonella foenum-graecum capable of curing Cellulitis. Molecular docking method applied using “Biovia Discovery Studio”. “The experiment shows that the phytochemical sarginine, carpaine, choline, gentianine and diosgenin failed to deactivate the UDP-glucose 6-dehydrogenase enzyme of Streptococcus pyogenes for treating Cellulitis.
Trigonella foenum-graecum Derived Phytochemicals against Cough
Authors: Tripathy Bidyashree , Sahoo Elina , Jha Sunil , Bhattacharyay Dipankar 
Published: July 2020

Phytochemicals from Trigonella foenum-graecum plant extract are traditionally used to cure Cough. There are many reasons for cough. It has been reported that cough can be caused as a result of Bordetella sp. infection. The objective of the study is to identify the phytochemical of Trigonella foenum-graecum capable of curing Cough. Molecular docking method applied using “Biovia Discovery Studio”. The research clearly indicates that choline, arginine, and gentianine cannot effectively deactivate the enzyme histidinekinase of the microbe. On the other hand, carpaine and diosgenin failed to deactivate the enzyme. Thus, none of these phytochemicals can effectively deactivate the histidinekinase enzyme of Bordetella sp. and thus cannot be used to treat cough caused by this particular microbe.
Michelia champaca L. Derived Phytochemicals against Peptidase Do of Bordetella pertussis Causing Cough
Authors: Dash Sanjeeb Kumar , Ray Sidhartha , Behera Smruti Ranjan , Jal Soumya , Bhattacharyay Dipankar 
Published: July 2020

Phytochemicals from Michelia champaca L. plant extract are traditionally used to cure cough. Cough can be caused by many reasons. Caugh can be caused by the infection of Bordetella pertussis. The objective of the study is to identify the phytochemical of Michelia champaca capable of curing cough. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that magnoflorine can effectively deactivate the peptidase Do enzyme which will interrupt the life cycle of the microorganism and inhibit the multiplication.
Quantum Point Defects for Solid‐State Laser Refrigeration
Authors: Xia Xiaojing , Pant Anupum , Ganas Abbie S. , Jelezko Fedor , Pauzauskie Peter J. 
Published: July 2020

AbstractHerein, the role that point defects have played over the last two decades in realizing solid‐state laser refrigeration is discussed. A brief introduction to the field of solid‐state laser refrigeration is given with an emphasis on the fundamental physical phenomena and quantized electronic transitions that have made solid‐state laser‐cooling possible. Lanthanide‐based point defects, such as trivalent ytterbium ions (Yb3+), have played a central role in the first demonstrations and subsequent development of advanced materials for solid‐state laser refrigeration. Significant discussion is devoted to the quantum mechanical description of optical transitions in lanthanide ions, and their influence on laser cooling. Transition‐metal point defects have been shown to generate substantial background absorption in ceramic materials, decreasing the overall efficiency of a particular laser refrigeration material. Other potential color centers based on fluoride vacancies with multiple potential charge states are also considered. In conclusion, novel materials for solid‐state laser refrigeration, including color centers in diamond that have recently been proposed to realize the solid‐state laser refrigeration of semiconducting materials, are discussed.
Luminescent Nd3+‐Based Microresonators Working as Optical Vacuum Sensors
Authors: Soler‐Carracedo Kevin , Martin Inocencio R. , Runowski Marcin , Martín Leopoldo L. , Lahoz Fernando , Lozano‐Gorrín Antonio D. , Paz‐Buclatin Franzette 
Published: July 2020

AbstractGlass microspheres embedded with Nd3+‐doped nanoperovskites based on yttrium orthoaluminate are synthesized and used as optical vacuum sensor. Under 532 nm excitation, the microspheres show two emission bands centered at 820 and 890 nm, corresponding to the 2H9/2,4F5/2 → 4I9/2 and 4F3/2 → 4I9/2 transitions. When the microspheres are heated by laser excitation in air (ambient conditions), the positions of the Stark level transitions shift toward red or blue spectral regions. Additionally, the full width at half maximum of these peaks increases. Furthermore, due to the specific geometry of the microspheres, it is possible to trap the emitted light inside the microsphere resonator, in the form of whispering‐gallery‐modes (WGM). When the microspheres are heated, these resonant modes present higher shifts toward lower energies than those for the Stark levels. As pressure decreases, the thermal exchange (convection process) between the microsphere and the surrounding air molecules decreases, which leads to an increase on the temperature of the microsphere. Based on this effect, the response of the WGM spectral positions as a function of pressure level is used to calibrate the luminescent microspheres as optical vacuum sensors. Relative sensitivity and limit of detection are obtained and compared with other optical vacuum sensors.
Soil health management practices and crop productivity
Authors: Miner Grace L. , Delgado Jorge A. , Ippolito James A. , Stewart Catherine E. 
Published: July 2020

AbstractGlobally, food systems face multiple challenges, including minimizing environmental impacts, adapting to a changing climate, increasing yields, and maintaining and/or increasing crop nutritional quality. Management techniques that focus on soil health (SH) are promising solutions to mitigate some environmental impacts and may increase economic returns. However, claims that SH increases will concurrently increase crop quality and productivity merit careful examination. Factors beyond SH metrics determine crop nutritional quality. Yield outcomes of SH management are of significance, as there are concerns that yield increases are insufficient to meet future food demands. While SH frameworks are comparatively recent initiatives, there are thousands of published conservation agriculture studies that examine yield outcomes with cover crops, no‐till, and rotation. This literature indicates that SH practices can also have neutral or negative yield impacts—only in select systems have consistent yield increases been realized, highlighting the need for language clarification and improvements in mechanistic understanding of regional‐scale yield impacts.
Role of Singlet and Triplet Excitons on the Electrical Stability of Polymer Light‐Emitting Diodes
Authors: vander Zee Bas , Paulus Sarina , Png Rui‐Qi , Ho Peter K. H. , Chua Lay‐Lay , Wetzelaer Gert‐Jan A. H. , Blom Paul W. M. 
Published: July 2020

AbstractStability under electrical stress is an important aspect for the function of organic light‐emitting diodes (OLEDs). Degradation is currently one of the key topics in this field, concerning all types of OLEDs, including fluorescent‐, phosphorescent‐, and thermally activated delayed fluorescence‐based OLEDs. For single‐layer polymer light‐emitting diodes (PLEDs) it has recently been found that degradation is the result of hole trap formation due to exciton–polaron interactions. However, whether singlet or triplet excitons are responsible for degradation is an open question. Here, their contributions are disentangled by systematically manipulating the singlet and triplet exciton populations and their effect on PLED degradation is studied. To control singlet excitons the emission of a blue‐emitting PLED is modified to green by adding a small amount of a perylene‐monoimide based green‐emitting dye. The triplet population is manipulated by blending the light‐emitting polymer with a dye that has either a longer or shorter triplet lifetime as compared to the polymer host. The results reveal that the degradation in fluorescent PLEDs is governed by the interaction between polarons and triplet excitons.
PEDOT:PSS Microchannel‐Based Highly Sensitive Stretchable Strain Sensor
Authors: Bhattacharjee Mitradip , Soni Mahesh , Escobedo Pablo , Dahiya Ravinder 
Published: July 2020

AbstractThis paper presents poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate polymer microchannel (diameter ≈175 µm) based stretchable strain sensor developed inside polydimethylsiloxane substrate. The microchannel diameter changes when subjected to various strains, leading to change in the resistance of strain sensor. The sensor exhibits about three order (ΔR/R0 ≈ 1200) increase in the resistance (R) for 10% applied strain (ΔL/L, L = length of the sensor). This leads to a gauge factor (GF Δ (ΔR/R0)/(ΔL/L) of ≈12 000, which is about ≈400 times higher than most of the reported polymer‐based strain sensors. The sensor is evaluated up to a maximum strain of 30%, which is the standard strain limit associated with human body parts such as fingers and wrists. The sensor exhibits a considerably good average degree of hysteresis (<9%). Further, the sensor is also studied for bending and twisting experiments. A response of (ΔR/R0 ≈ 250) and (ΔR/R0 ≈ 300) is recorded for 90° bending and 150° twisting, respectively. The sensor shows an electrical resolution of ≈150% per degree of free bending and ≈12k% per percentage of stretching. Finally, the potential application of presented sensor in robotics and wearable systems is demonstrated by using sensor feedback from human hand to remotely control the robotic hand movements.