bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Remotely Delivered Light-Intensity Physical Activity Intervention for Older Cancer Survivors: Protocol for a Feasibility Randomized Controlled Trial
Authors: Blair Cindy K , Brown-Glaberman Ursa , Walters Scott T , Pestak Claire , Boyce Tawny , Barriga Laura , Burgess Ellen , Tawfik Bernard , Killough Cynthia , Kinney Anita Y , Demark-Wahnefried Wendy , Meisner Angela L , Wiggins Charles L , Pankratz V Shane , Davis Sally 
Published: December 2024

Background
Older cancer survivors face age- and treatment-related comorbidities, including physical functional impairment, which are exacerbated by physical inactivity and sedentary behavior. Regular physical activity can reduce this risk, yet less than 30% of older cancer survivors meet the recommended guidelines for physical activity.

Objective
This study aims to describe the design, methods, and rationale for a remotely delivered intervention that uses a whole-of-day approach to physical activity in older cancer survivors. This approach focuses on the accumulation of intermittent bouts of light-intensity activity throughout the entire day by disrupting and reducing sedentary activity. The intervention was guided by social cognitive and self-determination theories and incorporated motivational interviewing.

Methods
The 12-week Move for Your Health trial randomly assigned 64 older cancer survivors to a theory-based physical activity intervention or a waitlist control. A Fitbit (Google) activity tracker and smartphone app were used to promote awareness of activity levels and enable self-monitoring of both activity and inactivity in tandem with health coaching phone calls. Motivational interviewing was used to engage participants and tailor strategies to achieve goals during the 12-week intervention. Data were collected at baseline, immediately after the intervention, and at longer-term follow-up (3 months thereafter). Feasibility outcomes included recruitment, retention, adherence, adverse events, and acceptability. Other outcomes included obtaining the parameter estimates for changes in physical function, physical performance, physical activity, sedentary behavior, and quality of life.

Results
Recruitment for the Move for Your Health randomized controlled trial was completed in June 2023. Data collection was completed in March 2024. Data analyses are ongoing.

Conclusions
The results of this trial will provide information on the feasibility of implementing this intervention in the target patient population, as well as data that will provide information about the potential impact of the intervention on the outcomes. Both of these outcomes will inform the design of a larger randomized controlled trial to more fully test a physical activity intervention in an older cancer survivor population.

Trial Registration
ClinicalTrials.gov NCT05582889; https://clinicaltrials.gov/study/NCT05582889

International Registered Report Identifier (IRRID)
DERR1-10.2196/59504
PREDICTIVE VALUE OF TUMOR SIZE ON THE INCIDENCE OF PERITUMORAL EDEMA ON PRE-SURGERY HEAD MRI OF MENINGIOMA PATIENTS
Authors: Pangestu Rahmawati Dianing , Faisal Arif , Utomo Bambang Purwanto 
Published: December 2024

Background : Peritumoral brain edema (PTBE) of meningioma causes morbidity, poor clinical outcomes and complicates surgery. Tumor size correlates with the incidence of PTBE. However, the threshold value for tumor size that cause PTBE in meningioma has not been widely studied. Objective: To determine the threshold value for meningioma size that can predict the incidence of peritumoral edema in general and based on specific intracranial locations on pre-operative head MRI.Methods: This is a cross sectional study on patients with intracranial meningioma who had undergone head MRI imaging at Dr.Sardjito Hospital in the period of 2018-2022 retrospectively. An analysis was carried out to find the threshold value for meningioma size and the prevalence ratio to predict the incidence of PTBE. Results: The cut-off volume for intracranial meningioma was >44 cm3 with RP of 3.61 (p=0.01) in general. Simultaneously, large tumor volume (≥44 cm3) has the strongest correlation to the incidence of peritumoral edema (p=0.01). The cut-off volume for meningioma in supratentorial non-skull base was >22 cm3 with RP of 2.54, while in supratentorial skull base was >54 cm3 with RP of 23.33 (p=0.01). The cut off volume for meningioma in infratentorial region was >19.75 cm3 with RP 3.0 (p=0.52). Conclusion: The cut-off value for intracranial meningioma volume to predict the incidence of peritumoral edema is 44 cm3. There are differences in the cut-off values of meningioma volume and prevalence ratios based on specific intracranial locations to predict the incidence of PTBE in meningioma.
Relationship between Microvascular Complications and Elevated Neutrophil-to-Lymphocyte Ratio in Patients with Diabetes Mellitus
Authors: Rico-Chávez Pedro , Pérez-Pérez Mireya , Reyes-Jiménez Olivia 
Published: December 2024

Objective: To evaluate the relationship between microvascular complications and elevated neutrophil-to-lymphocyte ratio (NLR) values in patients with type 2 diabetes mellitus (T2DM) from a family medicine unit. Methods: A cross-sectional analytical study was conducted at Family Medicine Unit 92 of the Mexican Institute of Social Security. A total of 232 medical records of T2DM patients were analyzed through probabilistic sampling. A data collection form, designed by the researchers, was used to collect sociodemographic, biochemical, and clinical variables, which were analyzed with GraphPad Prism 10 using χ2 and Student’s t-tests. Results with a p-value <0.05 were considered statistically significant. Results: NLR was calculated for each medical record, and it was found that 51 patients (22%) had elevated NLR values. Elevated nlr was associated with sex, hypertension, and poor glycemic control (p<0.05) but not with body mass index (BMI), age, and duration of T2DM. A statistically significant relationship was observed between elevated nlr and the presence of microvascular complications such as nephropathy, neuropathy, cardiopathy, and retinopathy (p<0.05). Logistic regression analysis showed a significant association between elevated NLR and diabetic cardiopathy (OR: 7.93, 95% CI, 3.29-20.33, p<0.05). Conclusion: Elevated NLR values were associated with the presence of microvascular complications in t2dm patients, suggesting that nlr may be useful as a biomarker for managing diabetic patients in family medicine consultations.
Construindo a soberania sanitária no Mercosul: a experiência do curso de desenvolvimento e produção de vacinas
Authors: Tobar Sebastián , Carlos Santos da Costa Jorge , Nakamura  Gouvea Mirian , Alberto Medeiros Marco , Fernandes Delgado Isabella 
Published: December 2024

Introduction: This paper reports on the experience of the Vaccine Development and Production Course, an initiative promoted by Fiocruz within the framework of the MERCOSUR Health Ministers’ Meetings. The experience was developed in the second half of 2023, with the participation of students from Argentina, Brazil, Paraguay, and Uruguay as member states of the bloc and Chile as an associate state. Objective: To support the hypothesis that we will only be able to advance health sovereignty in the field of vaccines if we simultaneously implement sovereignty in terms of strategy and the process of training human resources, articulating the region’s capabilities in a network. Method: This is a report that presents reflections onhealth sovereignty in the production of biological products, based on a training experience that involved the mobilisation of existing capacities at Fiocruz, Instituto Butantan and Nortec, based on synchronous remote classes and personal technical visits. Results: Details of this experience were presented and based on this, we sought to outline appropriate strategies for continuing professional development in the region, with the aim of achieving health sovereignty in terms of regional vaccine production with a view to self-sufficiency. Conclusions: It is noted that despite the language barriers and institutional differences between the bloc and the associated countries, the evaluation carried out at the end of the course confirms the relevance and the need to expand experiences such as the one developed. The need to create capacities in the region to effectively achieve health sovereignty is evident, as well as the importance of incorporating some strategic themes identified by the students to continue the qualification of professionals in the region, in a continuous and permanent training process.
Типология местообитаний цианопрокариот арктических экосистем на примере анализа флоры архипелага Шпицберген
Authors: Давыдов Д.А. 
Published: December 2024

В работе предложена основа классификации местообитаний цианопрокариот арктических территорий, построенная на Европейской информационной системе природы (EUNIS). Выделены две больших группы местообитаний: пресноводные и наземные. Последняя, в свою очередь, разделена на амфибиальную и типично наземную подгруппы. Вариабельность полярных местообитаний можно представить в виде градиента увлажнения, который проходит от пресноводных через субаэрофитные до сухих типично наземных. Различия периодичности, амплитуды и регулярности увлажнения местообитаний приводят к дифференцировке видового состава цианопрокариот. Наиболее благоприятными для них в условиях архипелага Шпицберген являются: 1) скальные сообщества с достаточным увлажнением, 2) оголенные грунты, на которых формируются биологические почвенные корочки, 3) медленные хорошо прогреваемые ручьи, 4) специфические переувлажненные местообитания – просачивания.
This study proposes a framework for classifying the habitats of cyanoprokaryotes in Arctic regions, based on the European Nature Information System (EUNIS). Two major habitat groups are identified: freshwater and terrestrial. The latter is further subdivided into subaerophytic (those at the boundary between aquatic and aerophytic environments) and aerophytic (found on rocky substrates and soil surfaces). The variability of polar habitats can be represented along a moisture gradient, ranging from freshwater, through subaerophytic zones, to dry terrestrial environments. Differences in the frequency, amplitude, and regularity of habitat moisture levels lead to the differentiation of cyanoprokaryotes species composition. In the Svalbard Archipelago, four particular habitats support greater diversity and abundance of cyanoprokaryotes: 1) wet walls and rocks, 2) bare soils and biocrust communities, 3) warm, slow-flowing streams, and 4) specific over-moistened habitats – seepages.
Особенности видового состава флоры в фитоценозах с участием Acer negundo в Кузбассе
Authors: Цандекова О.Л. 
Published: December 2024

В статье представлены результаты изучения видового состава сосудистых расте- ний в фитоценозах с участием Acer negundo, расположенных в горно-таежной и лесостепной зонах Кемеровской области. Выявлено присутствие 41 вида сосудистых растений из 36 родов и 17 семейств. Под пологом A. negundo преобладали рудеральные виды – Cirsium setosum, Elytrigia repens, Urtica dioica, тогда как во внешних зонах возрастало количество луговых видов – Achillea millefolium, Dactylis glomerata, Festuca pratensis. Видовое разнообразие в сообществах с участием клена ясенелистного было в среднем на 55% ниже, чем в растительных сообществах без данного вида. В горно-таежной и лесостепной зонах видовое разнообразие уменьшилось в 1.7 и 2.8 раза соответственно.
The article presents the study results of the species composition of vascular plants in phyto- cenoses with Acer negundo located in the mountain-taiga and forest-steppe zones of Kemerovo Oblast. We have identified 41 species of vascular plants from 36 genera and 17 families. Under the canopy of A. negundo, ruderal species (Cirsium setosum, Elytrigia repens, Urtica dioica) prevailed, however, beyond this zone the number of meadow species (Achillea millefolium, Dactylis glomerata, Festuca pratensis) increased. Species diversity in the plant communities with box elder involvement was on av- erage 55% lower than in those where this species was absent. In the mountain-taiga and forest-steppe zones, species diversity of plants declined by 1.7 and 2.8 times, respectively.
Сроки осенней миграции дендрофильных птиц в лесостепном Зауралье
Authors: Тарасов В.В. , Ляхов А.Г. 
Published: December 2024

Представлены результаты исследования динамики осеннего пролета мелких птиц, полученные в ходе их отловов паутинными сетями в Курганской области в 2013, 2014 и 2016 гг. Изучены 55 видов. Показаны изменения их относительного обилия с конца июля до середины октября. Для большинства видов установлены сроки начала, окончания и пика миграционной активности. Определена очередность их отлета из региона, произведена классификация по характеру динамики и количеству основных волн пролета, выявлены доминирующие в отловах виды как за весь период миграции, так и на разных ее этапах. Обсуждаются долговременные изменения сроков осенней миграции птиц в лесостепном Зауралье, ее направление, длительность остановок, сроки пролета особей из разных половозрастных групп.
The article presents the results of a study of the dynamics of autumn migration of small birds obtained during their captures with mist nets in the Kurgan Oblast in 2013, 2014 and 2016. Overall, we studied 55 species and report changes in their relative abundance from late July to mid-October as well as the starting, ending and peak dates of the migration for most species. Also, we determined the sequence of their departures from the region, classified the species by the dynamics and the number of main migration waves, defined the dominant species in the captures both for the entire migration period and for its different stages. Moreover, in the article we discuss long-term changes in the timing of autumn bird migration in the forest-steppe Trans-Urals, its direction, duration of stops, timing of migration of individuals from different age and sex groups.
Diet type, fasting duration, and computed tomography hepatic attenuation influence postprandial plasma lipids, β-hydroxybutyric acid, glucose, and uric acid in bearded dragons (Pogona vitticeps)
Authors: Sosa-Higareda Mariana , Beaufrère Hugues 
Published: December 2024

Abstract

OBJECTIVE
To evaluate the effect of fasting duration and diet types (plant-based and crickets) on plasma glucose, uric acid, cholesterol, triglycerides, nonesterified fatty acid, β-hydroxybutyric acid (BHBA), and bile acids in bearded dragons after a single feeding.

METHODS
Hepatic fat content was estimated by a CT scan. Animals were randomly divided into 2 groups, each receiving either a plant-based or cricket diet. Following a 72-hour fasting period, animals were gavage fed their respective diets. Blood samples were collected at 0, 6, 12, 24, 48, and 72 hours postfeeding for biochemistry analysis. Data were analyzed using linear mixed models.

RESULTS
22 bearded dragons were used. Plasma glucose, uric acid, bile acid, nonesterified fatty acid, and BHBA concentrations varied significantly over time between the 2 diets. Cholesterol and triglycerides remained stable throughout the fasting period. Glucose peaked for 48 hours in the plant-based group. Uric acid increased in the cricket group but declined in the plant-based group. Bile acids increased in both groups, with a more pronounced and sustained increase in the cricket group. Nonesterified fatty acid and BHBA decreased within the first 12 hours in both groups, with a subsequent rebound, except for BHBA in the plant-based group. Hepatic CT attenuation significantly influenced multiple analytes.

CONCLUSIONS
A fasting period of 48 to 72 hours depending on analytes is recommended in bearded dragons before biochemistry analysis.

CLINICAL RELEVANCE
Fasting periods shorter than 48 to 72 hours may lead to erroneous interpretation of plasma biochemistry in bearded dragons. The findings of this study also suggest a feeding frequency of 2 to 3 days for adult bearded dragons.
Distal teat amputation for distal papillary canal injuries in lactating dairy cows
Authors: Klostermann Cassandra A. , Babkine Marie , Desrochers André , Lardé Hélène , Nichols Sylvain 
Published: December 2024

Abstract

OBJECTIVE
The objectives were to describe a distal teat amputation and determine the long-term outcomes in dairy cows.

METHODS
This retrospective study examined medical records of 22 lactating dairy cows admitted to the Farm Animal Hospital from 2015 to 2021 for distal teat and papillary canal injuries that received a distal teat amputation as the sole surgical treatment. Long-term follow-up was obtained from the Canadian Dairy Network (CDN) and milk producers to determine whether the cows remained in the herd and identify whether any factors affected this outcome.

RESULTS
The hindquarters were affected in 18 of the 22 distally amputated teats (82%; 95% CI, 66% to 98%). Mastitis was the most common postoperative complication. Of the 22 cows, CDN and follow-up information was available for 18 cows (82%). Of these 18 cows, 13 (72%; 95% CI, 51% to 93%) remained in the herd for at least the start of a subsequent lactation following surgery.

CONCLUSIONS
Lactating dairy cows had a favorable chance of remaining in the herd following a distal teat amputation.

CLINICAL RELEVANCE
Decreased milking efficiency caused by distal teat injuries can be a source of economic loss for the milk producer. Distal teat amputation to reestablish milk flow was a practical procedure that required attentive postoperative care.
Evaluation of Chlorella vulgaris S45 Application on Swiss Chard (Beta vulgaris L. subsp. cicla) Seed Germination, Pigment Content, Total Phenolic Content and Antioxidant Activity
Authors: Jafari Timea Hajnal , Žunić Vladimira , Stamenov Dragana , Đurić Simonida , Pavlović Ružica Ždero , Popović Boris 
Published: December 2024

Summary
Contemporary agriculture faces the challenge of sustainably feeding constantly growing human population. Application of green algae in plant production is a new, relatively low-cost green technology with potential benefits for plant health. This study examines the application of Chlorella vulgaris S45 and its effect on seed germination, pigment content, total phenolic content and antioxidant capacity of Swiss chard. Treatments included 5% and 10% algal suspensions applied by spraying on plants and in substrate, respectively. C. vulgaris S45 positively affected all the investigated parameters. Seed germination percentage (GP) increased in comparison to the control treatment. The highest GP (46%) and germination index (GI) values were observed in the 10% suspension treatment. Photosyntetic pigment content also increased significantly under 10% suspension application, while both total phenol content and antioxidant capacity improved following plant spraying with 10% suspension. Correlation analysis indicated statistically significant interdependence among the tested parameters (pigment content, total phenolic content and antioxidant activity). Foliar application of Chlorella vulgaris S45 could be an alternative fertilization method in sustainable Swiss chard production.
Occurrence of Aflatoxin B1 in Corn in Vojvodina, Republic of Serbia, Over the Last Fourteen Years (2010-2023)
Authors: Horvatović Miroslava Polovinski , Krstović Saša , Jajić Igor , Guljaš Darko , Damjanović Marko 
Published: December 2024

Summary
Mycotoxins, including aflatoxins, are pervasive contaminants in crops worldwide, with aflatoxin B1 being particularly significant due to its effects on agricultural production and food safety. Serbia has a well-developed crop production sector. The increasing risk of aflatoxin contamination in certain parts of Europe, particularly the Balkan Peninsula, became evident during the 2013 outbreak. This study presents the results of 14-year monitoring (2010–2023) of corn for the occurrence of aflatoxin B1 in the Republic of Serbia. A total of 1167 samples were analyzed, of which 422 samples (36%) exceeded the limit of quantification. Among these, 183 samples were above the EU regulatory limits (EC, 2002), while 150 samples were above the regulatory limits of the Republic of Serbia. The year 2012 was particularly prominent for the high occurrence and concentration of aflatoxin B1 (AFB1) in corn, when 128 out of 132 samples tested positive for AFB1. The average concentration in all positive samples was 55±57 µg kg-1, with a maximum value of 367 µg kg-1, which exceeded the Serbian legal limit by over ten times and the EU limit by more than fifteen times. High incidence of AFB1 in analyzed samples was also in 2022, with 61% of samples exceeding the AFB1 limit of quantification. The average concentration in 2022 was 47±81 µg kg-1, with a maximum recorded value of 560 µg kg-1. The results indicate that aflatoxin B1 will remain a persistent challenge in crop production, with certain years exhibiting exceptionally high levels of contamination.
Determinants of Profitability of Grain Production Enterprises from Ap Vojvodina
Authors: Novaković Dragana , Milić Dragan , Zekić Vladislav , Vukelić Nataša , Novaković Tihomir , Jocić Bogdan , Erak Dejan 
Published: December 2024

Summary
This study calculates profitability and identifies the determinants influencing the profitability of enterprises engaged in growing cereals (except rice), leguminous crops and oilseeds in AP Vojvodina in 2022. The analysis is based on data from 320 small and medium-sized agricultural enterprises using multiple linear regression, with Return on Assets (ROA) as the dependent variable. Descriptive statistics showed a median ROA of 2.62%, indicating relatively low profitability. The regression model revealed that liquidity, indebtedness, asset structure, total asset turnover ratio and company size significantly impact profitability. Liquidity and indebtedness negatively affect profitability, suggesting unproductive resource use and high debt levels. Asset structure also negatively impacts profitability, indicating inefficient use of fixed assets. Conversely, the total asset turnover ratio and company size positively influence profitability, reflecting efficient asset use and better investment opportunities. The study recommends better liquidity management, debt reduction, optimizing asset structure, increasing asset turnover efficiency, and leveraging company size to improve profitability. These strategies can enhance financial performance and competitiveness, contributing to the sustainable growth of agricultural enterprises in Vojvodina.