bluuebunny/crossref_metadata_2025_split huggingface dataset:
Markov Chain Analysis- A Discrete Assessment on Livestock Sector Trade in India and Allied Countries
Authors: Sonavale K. P. , Kadam M. M. , Shaikh M. R. , Pokharkar V. G. 
Published: August 2020

Objective/Methods: The research was to analyze the export and import of livestock products (India) to Oman, Afghanistan, Liberia, Maldives, Algeria, Bangladesh, Kuwait, Vietnam, Philippines, Jordon and Saudi Arabia and U.A.E countries through Markov-chain analysis, and to identify the important factors responsible for livestock production. The Markov chain Analysis was employed to analyse the dynamic nature of trade pattern specially the structural changes in any system whose progress through time can be measured in the term of single outcome variable. To accomplish the objective under study the period taken for all livestock products export was 2006-2007 to 2017-2018.
Findings/Applications: The study on import and export of agricultural commodities revealed a significant benchmark based on Markov chain analysis. The Markov Chain analysis revealed that, India has an edge to export milk products to Algeria, Bangladesh and U.A.E, as indicated by the highest retention probability. In case of egg, export to Oman, Afghanistan, Liberia, Maldives indicated by the highest retention capacity. In case of buffalo meat, export to Vietnam, Philippines, Jordon and Saudi Arabia as indicated by the highest retention probability. In case of sheep meat, export to Saudi Arabia, Oman and Kuwait had the highest retention probability. The multiple linear regression analysis indicated that the factors for milk production (number of buffaloes, Area under permanent Pasture and Grazing land and institutional credit), for meat production (number of animals slaughtered, population of poultry, buffalo, sheep and goat, number of veterinary institutes) and for egg production (Number of layers and number of veterinary institutes) were highly significant to increase the livestock product production.
The Impact of the Lockdown Measure on the Confirmed Cases of the Novel Coronavirus (COVID-19) in Nigeria
Authors: Aronu Charles Okechukwu , Otty Nkechi Udochukwu , Ehiwario Jacob Chinedum , Okafor Patrick Nnaemeka 
Published: August 2020

Aims: This study examined the impact of the lockdown measure on the confirmed cases of the Novel Coronavirus (COVID-19) in Nigeria. The objectives of the study include to identifying an appropriate autoregressive integrated moving average (ARIMA) model that is adequate for estimating the reported cases of COVID-19 in Nigeria and to ascertain whether the ease of lockdown has a significant impact on the reported cases of COVID-19 in Nigeria.
Place and Duration of Study: The source of the data used for this study was the secondary data obtained from the daily report of the United Nations Office for the Coordination of Humanitarian Affairs (OCHA) from 1st February 2020 to 30th June 2020.
Methodology: The statistical tools used for data analysis are the ARIMA time series model and the Chow test analysis.
Results: Nigeria ranked 1st in West Africa sub-region with a total of 25, 133 confirmed COVID-19 cases, followed by Ghana with 17, 351 confirmed cases while Gambia recorded the least number of confirmed cases with 47 cases of COVID19. The ARIMA (0, 1, 1) was identified as the best model for forecasting the confirmed COVID-19 cases in Nigeria within the observed period. It was found that there exists a significant difference in the number of confirmed cases of COVID-19 during the lockdown period and the post lockdown period.
Conclusion: The study revealed that Nigeria has the most confirmed cases of COVID-19 in West Africa region. Also, the ease of the lockdown was found to increase the number of confirmed virus cases in Nigeria.
Neuronal intranuclear inclusion disease is genetically heterogeneous
Authors: Chen Zhongbo , Yan Yau Wai , Jaunmuktane Zane , Tucci Arianna , Sivakumar Prasanth , Gagliano Taliun Sarah A. , Turner Chris , Efthymiou Stephanie , Ibáñez Kristina , Sullivan Roisin , Bibi Farah , Athanasiou‐Fragkouli Alkyoni , Bourinaris Thomas , Zhang David , Revesz Tamas , Lashley Tammaryn , DeTure Michael , Dickson Dennis W. , Josephs Keith A. , Gelpi Ellen , Kovacs Gabor G. , Halliday Glenda , Rowe Dominic B. , Blair Ian , Tienari Pentti J. , Suomalainen Anu , Fox Nick C. , Wood Nicholas W. , Lees Andrew J. , Haltia Matti J. ,   Genomics England Research Consortium, Hardy John , Ryten Mina , Vandrovcova Jana , Houlden Henry 
Published: August 2020

AbstractNeuronal intranuclear inclusion disease (NIID) is a clinically heterogeneous neurodegenerative condition characterized by pathological intranuclear eosinophilic inclusions. A CGG repeat expansion in NOTCH2NLC was recently identified to be associated with NIID in patients of Japanese descent. We screened pathologically confirmed European NIID, cases of neurodegenerative disease with intranuclear inclusions and applied in silico‐based screening using whole‐genome sequencing data from 20 536 participants in the 100 000 Genomes Project. We identified a single European case harbouring the pathogenic repeat expansion with a distinct haplotype structure. Thus, we propose new diagnostic criteria as European NIID represents a distinct disease entity from East Asian cases.
Use of Ferritin Capped Mesoporous Silica Nanoparticles for Redox and pH Triggered Drug Release In Vitro and In Vivo
Authors: Cai Yao , Deng Tian , Pan Yongxin , Zink Jeffrey I. 
Published: August 2020

AbstractMesoporous silica nanoparticles (MSNs) functionalized with redox‐sensitive or pH‐sensitive nanovalves for doxorubicin delivery and release by using recombinant human H chain ferritin (HFn) as a cap have been designed and fabricated. In both cases, transmission electron microscope observatory, dynamic light scattering change, Fourier transform infrared spectra examination, thermogravimetric analysis show that HFn can be chemically bonded to MSNs while retaining its ability to target transferrin receptor 1 (TfR1). Cargo loading and release studies demonstrate that HFn is an efficient capping agent, blocking the pores of MSN preventing cargo molecules from diffusing out, and is responsive to redox stimuli or pH changes. More importantly, HFn can not only cap the MSNs, but also enables targeted cargo delivery to malignant cells by binding to the TfR1 that has been overexpressed in various tumors, which can be reflected by the cell viability and fluorescence microscope analysis results comparing with cyclodextrin as the capping agent and TfR1 blocking assay. The in vivo study reveals the excellent efficacy of doxorubicin loaded and HFn capped MSNs on suppression of tumor growth. The new developed drug delivery system features mutually benefit and mutually support, providing strategy for achieving specific‐site therapeutics delivery systems.
Improved Quantum Yield and Excellent Luminescence Stability of Europium‐Incorporated Polymeric Hydrogen‐Bonded Heptazine Frameworks Due to an Efficient Hydrogen‐Bonding Effect
Authors: Yang Chaoqing , Folens Karel , Du Laing Gijs , Artizzu Flavia , Van Deun Rik 
Published: August 2020

AbstractTwo of the most persistent challenges for the high‐end application of luminescent lanthanide (Ln) compounds are a low quantum yield and luminescence quenching caused by a liquid medium. In this work, a type of polymeric hydrogen‐bonded heptazine framework is developed incorporating trivalent europium ions (P‐HHF‐Eu) via a low‐cost and facile low‐temperature thermal condensation reaction. Structural characterization clearly reveals that the solid‐phase pyrolyzation reaction results in the formation of P‐HHF‐Eu. Using time‐resolved and steady state photoluminescence (PL) spectroscopies, the photophysics and photochemistry of P‐HHF‐Eu at different hydration degrees are investigated and the role of hydrogen bonding in the significant enhancement of the emission properties is demonstrated. Furthermore, the P‐HHF‐Eu particles suspended in polyvinyl alcohol hydrogel exhibit excellent luminescence stability with a high PL quantum yield of up to ≈46% and wavelength responsive color‐tunable emission, which holds potential for security applications.
Bioresorbable Wireless Sensors as Temporary Implants for In Vivo Measurements of Pressure
Authors: Lu Di , Yan Ying , Deng Yujun , Yang Quansan , Zhao Jie , Seo Min‐Ho , Bai Wubin , MacEwan Matthew R. , Huang Yonggang , Ray Wilson Z. , Rogers John A. 
Published: August 2020

AbstractPressures at targeted locations inside the human body serve as critically important diagnostic parameters for monitoring various types of serious or even potentially fatal medical conditions including intracranial, intra‐abdominal, and pulmonary hypertension, as well as compartment syndromes. Implantable commercial sensors provide satisfactory accuracy and stability in measurements of pressure, yet surgical removal is required after recovery of the patient to avoid infections and other risks associated with long‐term implantation. Sensors that dissolve in biofluids (or, equivalently, bioabsorb or bioresorb) avoid the need for such surgeries, yet current designs involve either hard‐wired connections and/or fail to provide quantitative measurements over clinically relevant lifetimes. Here, a bioresorbable, wireless pressure sensor based on passive inductor‐capacitor resonance circuits in layouts and with sets of materials that overcome these drawbacks is reported. Specifically, optimized designs offer sensitivity as high as ≈200 kHz mmHg−1 and resolution as low as 1 mmHg. Encapsulation approaches that use membranes of Si3N4 and edge seals of natural wax support stable operation in vivo for up to 4 days. The bioresorbable pressure sensing technology reported here may serve as an important solution to temporary, real‐time monitoring of internal pressure for various medical conditions.
Self‐Assembly of Mechanoplasmonic Bacterial Cellulose–Metal Nanoparticle Composites
Authors: Eskilson Olof , Lindström Stefan B. , Sepulveda Borja , Shahjamali Mohammad M. , Güell‐Grau Pau , Sivlér Petter , Skog Mårten , Aronsson Christopher , Björk Emma M. , Nyberg Niklas , Khalaf Hazem , Bengtsson Torbjörn , James Jeemol , Ericson Marica B. , Martinsson Erik , Selegård Robert , Aili Daniel 
Published: August 2020

AbstractNanocomposites of metal nanoparticles (NPs) and bacterial nanocellulose (BC) enable fabrication of soft and biocompatible materials for optical, catalytic, electronic, and biomedical applications. Current BC–NP nanocomposites are typically prepared by in situ synthesis of the NPs or electrostatic adsorption of surface functionalized NPs, which limits possibilities to control and tune NP size, shape, concentration, and surface chemistry and influences the properties and performance of the materials. Here a self‐assembly strategy is described for fabrication of complex and well‐defined BC–NP composites using colloidal gold and silver NPs of different sizes, shapes, and concentrations. The self‐assembly process results in nanocomposites with distinct biophysical and optical properties. In addition to antibacterial materials and materials with excellent senor performance, materials with unique mechanoplasmonic properties are developed. The homogenous incorporation of plasmonic gold NPs in the BC enables extensive modulation of the optical properties by mechanical stimuli. Compression gives rise to near‐field coupling between adsorbed NPs, resulting in tunable spectral variations and enhanced broadband absorption that amplify both nonlinear optical and thermoplasmonic effects and enables novel biosensing strategies.
Evaporated SexTe1‐x Thin Films with Tunable Bandgaps for Short‐Wave Infrared Photodetectors
Authors: Tan Chaoliang , Amani Matin , Zhao Chunsong , Hettick Mark , Song Xiaohui , Lien Der‐Hsien , Li Hao , Yeh Matthew , Shrestha Vivek Raj , Crozier Kenneth B. , Scott Mary C. , Javey Ali 
Published: August 2020

AbstractSemiconducting absorbers in high‐performance short‐wave infrared (SWIR) photodetectors and imaging sensor arrays are dominated by single‐crystalline germanium and III–V semiconductors. However, these materials require complex growth and device fabrication procedures. Here, thermally evaporated SexTe1‐x alloy thin films with tunable bandgaps for the fabrication of high‐performance SWIR photodetectors are reported. From absorption measurements, it is shown that the bandgaps of SexTe1‐x films can be tuned continuously from 0.31 eV (Te) to 1.87 eV (Se). Owing to their tunable bandgaps, the peak responsivity position and photoresponse edge of SexTe1‐x film‐based photoconductors can be tuned in the SWIR regime. By using an optical cavity substrate consisting of Au/Al2O3 to enhance its absorption near the bandgap edge, the Se0.32Te0.68 film (an optical bandgap of ≈0.8 eV)‐based photoconductor exhibits a cut‐off wavelength at ≈1.7 μm and gives a responsivity of 1.5 AW−1 and implied detectivity of 6.5 × 1010 cm Hz1/2 W−1 at 1.55 μm at room temperature. Importantly, the nature of the thermal evaporation process enables the fabrication of Se0.32Te0.68‐based 42 × 42 focal plane arrays with good pixel uniformity, demonstrating the potential of this unique material system used for infrared imaging sensor systems.
Effect of Porous and Nonporous Nanostructures on the Permeance of Positively Charged Nanofilm Composite Membranes
Authors: Sarkar Pulak , Modak Solagna , Karan Santanu 
Published: August 2020

AbstractThe role of the nanostructured materials incorporated in the separation layer of thin‐film composite membranes is not properly understood yet, as it requires stringent salt rejection values, proper imaging of the separation layer to realize the presence of nanostructured materials, and to know the thickness of the separation layer. Here, the scalable fabrication of high flux positively charged “polyamide composite nanofiltration” membranes with an ultrathin nanofilm separation layer of ≈14 nm produced via interfacial polymerization of polyethyleneimine and trimesoyl chloride is presented. “Polyamide nanocomposite nanofiltration” membranes are fabricated with the incorporation of different porous and nonporous nanostructures (e.g., ZIF‐8, TiO2, and Fe2O3 nanoparticles, graphene oxide, multi‐walled carbon nanotube, etc.) within the nanofilm separation layer. High water permeance of 15.4 L m−2 h−1 bar−1 (an increase of 33.9% compared to the pure nanofilm) is achieved with high rejection of MgCl2 (97.6%). Such membranes with enhanced water permeance surpass the upper bound of the permeance‐rejection of the state‐of‐the‐art positively charged nanofiltration membranes applicable for ionic and molecular separation.
Lipid Droplet‐Targetable Fluorescence Guided Photodynamic Therapy of Cancer Cells with an Activatable AIE‐Active Fluorescent Probe for Hydrogen Peroxide
Authors: Jiang Guoyu , Li Chunbin , Liu Xiang , Chen Qingqing , Li Xiaokang , Gu Xinggui , Zhang Pengfei , Lai Qingfang , Wang Jianguo 
Published: August 2020

AbstractFluorescence guided photodynamic therapy (FL‐PDT) offers the great opportunity for realizing personalized medicine in the treatment of cancer. Aggregation‐induced emission luminogens (AIEgens) with efficient emission and reactive oxygen species (ROS) generation even in the aggregated state are the ideal FL‐PDT photosensitizers to overcome the quenched fluorescence and ROS that traditional photosensitizers faced in PDT. Moreover, considering the higher levels of H2O2 in cancer cells than in normal cells and the fact that lipid droplet (LD) accumulation correlates to the enhanced survival rate of cancer cells in hypoxic conditions, it will be very interesting and rewarding to develop a LD‐targeted, H2O2 activatable AIE‐active photosensitizer for FL‐PDT. Thereafter, a LD‐targeted fluorescent probe TPECNPB is fabricated for H2O2‐activatable fluorescence guided PDT of cancer cells. AIE‐active TPECNPB exhibits the unique features of large Stokes shift (175 nm), superior photostability, and excellent selectivity toward H2O2. TPECNPB is able to selectively accumulate in LD and is activated by endogenous H2O2 for light‐up bioimaging in live MCF‐7 cells. In addition, H2O2‐activatable singlet oxygen generation and PDT of cancer cells has also been successfully implemented with TPECNPB. These prominent parameters would make TPECNPB a powerful toolbox for H2O2‐activatable and LD‐targetable fluorescence guided PDT of cancer cells.
Membrane‐Based Olefin/Paraffin Separations
Authors: Ren Yanxiong , Liang Xu , Dou Haozhen , Ye Chumei , Guo Zheyuan , Wang Jianyu , Pan Yichang , Wu Hong , Guiver Michael D. , Jiang Zhongyi 
Published: August 2020

AbstractEfficient olefin/paraffin separation is a grand challenge because of their similar molecular sizes and physical properties, and is also a priority in the modern chemical industry. Membrane separation technology has been demonstrated as a promising technology owing to its low energy consumption, mild operation conditions, tunability of membrane materials, as well as the integration of physical and chemical mechanisms. In this work, inspired by the physical mechanism of mass transport in channel proteins and the chemical mechanism of mass transport in carrier proteins, recent progress in channel‐based and carrier‐based membranes toward olefin/paraffin separations is summarized. Further, channel‐based membranes are categorized into membranes with network structures and with framework structures according to the morphology of channels. The separation mechanisms, separation performance, and membrane stability in channel‐based and carrier‐based membranes are elaborated. Future perspectives toward membrane‐based olefin/paraffin separation are proposed.
Water‐Assisted Crystal Growth in Quasi‐2D Perovskites with Enhanced Charge Transport and Photovoltaic Performance
Authors: Li Xing , Wu Guangbao , Wang Mingchao , Yu Buyang , Zhou Jiyu , Wang Boxin , Zhang Xuning , Xia Haoran , Yue Shengli , Wang Kaiyuan , Zhang Chunfeng , Zhang Jianqi , Zhou Huiqiong , Zhang Yuan 
Published: August 2020

AbstractOrganic–inorganic hybrid quasi‐2D perovskites have shown excellent stability for perovskite solar cells (PSCs), while the poor charge transport in quasi‐2D perovskites significantly undermines their power conversion efficiency (PCE). Here, studies on water‐controlled crystal growth of quasi‐2D perovskites are presented to achieve high‐efficiency solar cells. It is demonstrated that the (BA)2MA4Pb5I16‐based PSCs (n = 5) processed with water‐containing precursors display an increased short‐circuit current density (Jsc) of 19.01 mA cm−2 and PCE over 15%. The enhanced performance is attributed to synergetic growths of the 3D and 2D phase components aided by the formed hydration (MAI∙H2O), leading to modulations on the crystal orientation and phase distribution of various n‐value components, which facilitate interphase charge transfer and charge sweepout throughout the device. The water‐assisted crystallization is further applied to triple cation‐based (BA)2(MA0.8FA0.15Cs0.05)4Pb5I16 quasi‐2D perovskites, which generate a remarkable PCE of 18.04%. Despite the presence of water in the precursors, the devices exhibit a satisfactory thermal stability with the PCE degradation <15% under continuous thermal aging at 60 °C for over 500 h.
Do investments in flexibility enhance sustainability? A simulative study considering the German electricity sector
Authors: Schäfer Pascal , Daun Torben M. , Mitsos Alexander 
Published: August 2020

AbstractCurrent research concerning industrial demand side management primarily focuses on monetary aspects. Herein, we extend this perspective by assessing whether economically driven measures increasing the flexibility also result in reduced contributions to the residual load. For this purpose, we conduct a simulative study using historic and projected time series for the German electricity sector. First, Fourier analysis are performed to show that the main oscillation in the electricity price time series has a period length of 12 hr, whereas the renewable generation is primarily characterized by an oscillation with a period length of 24 hr. Second, a generic process model with capabilities for load shiftings is used to evaluate how the fluctuation patterns can be exploited via scheduling optimizations. Most importantly, our results demonstrate that prevalent price fluctuations prevent adequate monetary incentives for providing storage capacities for bridging up to 24 hr, which are desired for reducing the residual load.
Survival analysis in treated plasmablastic lymphoma patients: a population‐based study
Authors: Florindez Jorge A. , Alderuccio Juan P. , Reis Isildinha M. , Lossos Izidore S. 
Published: August 2020

AbstractHerein we analyzed survival outcomes in chemotherapy‐treated patients with plasmablastic lymphoma (PBL) diagnosed between 2010 to 2016 (n = 248). Data was acquired from the Surveillance, Epidemiology, and End Results (SEER) 18 registries database (April 2019 release based on November 2018 submission). The majority of patients were male (81.9%) and younger than 60 years (71.0%). Oral and gastrointestinal (GI) sites were the most frequent primary extranodal locations (23% and 19.4%, respectively). Oral primary location was inversely associated with presence of B symptoms and advanced Ann‐Arbor stage. The 3‐year and 5‐year overall survival (OS) rates of treated PBL patients were 54% (95% CI: 46.5%‐60.8%) and 52.8% (95% CI: 45.2%‐59.8%). Three‐year conditional survival for 2‐year and 3‐year survivors were 90.3% and 97.8%, overlapping the survival of a general population matched by age, sex and calendar year. In a multivariable analysis, oral primary location was associated with not only better OS (HR 0.43; 95% CI: 0.21‐0.88, P = .021) but also better lymphoma‐specific survival (LSS) (SHR 0.36; 95% CI: 0.15‐0.86, P = .022); age ≥60 years was associated with shorter LSS (SHR 1.73; 95% CI: 1.02‐2.96, P = .043). Seven registries granted access to HIV status (n = 93) where HIV infection was detected in 52.7% of cases. The HIV status did not affect survival outcomes in unadjusted and adjusted analyses. We identified clinical characteristics associated with survival and showed that treated PBL patients may achieve long‐term survival.
Cyclic 1‐Azadienes in the Organocatalytic Inverse‐Electron‐Demand Aza‐Diels‐Alder Cycloadditions
Authors: Skrzyńska Anna , Frankowski Sebastian , Albrecht Łukasz 
Published: August 2020

AbstractThe inverse‐electron‐demand hetero‐Diels‐Alder (IEDHDA) reaction constitutes a useful and highly reliable method for the construction of various heterocycles. In the manuscript, a recent progress in the organocatalytic IEDHDA cycloaddition using cyclic 1‐azadienes as hetero‐dienes has been summarized and discussed. Since 2010 many interesting, new reactions involving these substrates have been identified and developed. They are based on various organocatalytic activation modes providing access to valuable nitrogen‐heterocycles. Excellent stereochemical reliability of asymmetric organocatalysis combined with the importance of the structural motifs obtained as a result of the cycloaddition makes these strategies highly relevant for the contemporary organic synthesis.
Evolution of Strategies in Paraconic Acids Synthesis
Authors: Fernandes Rodney A. , Chaudhari Dipali A. , Jha Amit K. 
Published: August 2020

AbstractVarious syntheses of different paraconic acids over the last seventeen years have been abstracted here. Paraconic acids have either a methylene or methyl group at the 4‐position of the γ‐butyrolactone with a common C‐3 carboxylic acid group and a long alkyl chain. Several possibilities of relative configurations give rise to distinct set of paraconic acids, which are also categorized in this review. Various strategies based on chiral catalytic methods, chiral pool, chiral auxiliary, resolution and other methods were engaged in the synthesis of different paraconic acids. A few members are yet to be synthesized and this compilation might entice future synthetic attempts on them.