bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Kemampuan Pemecahan Masalah Pada Materi Barisan dan Deret Kelas XI SMA
Authors: Safitri Alviani Milenia , Hadi Muhamad Sofian 
Published: December 2024

Mathematics is a very important lesson that is used in various aspects of life. NCTM math learning improves communication, problem-solving, relationships, and positive attitudes toward mathematics. Polya says problem solving consists of four stages: understanding problems, planning solutions, implementing plans, and producing results. The study investigated the ability of eleventh-grade students to solve problems with row and row material using Polya indicators. The study involved twenty students from UT Karya Dharma High School and used qualitative methods. The results of the analysis show that the problem-solving process is influenced by inexperience in understanding the problem. Students who understand the problem well tend to make mistakes in the application and evaluation formula, while students who lack understanding the problem solve through the stages correctly. Ineffective solutions arise from a less thorough understanding of the problem. It shows how important it is to understand the problem accurately before proceeding to the solution stage.
Cashless Commerce: A Study on the Interplay between Digital Payments and Luxury Consumption among Private Enterprises’ Employees
Authors: Salivio Micaela Pauline , Rillo Ana Catalina , Rosete Marie Antoinette 
Published: December 2024

Purpose: To explore how digital payment (independent variable) systems influenced purchasing behaviors (dependent variable) among employees in private enterprises, finding that factors such as convenience, speed, and flexibility drive luxury spending by simplifying high-value transactions. Although security risks and impulsive spending threaten the cashless situation, the urgency of such risks requires improved safeguards and better financial literacy.
Methodology: Stratified random sampling was applied by dividing the number of employees into distinct strata based on industry. A sample size was proportionally allocated to each stratum, ensuring equal representation from each category. This research was conducted in Iba, Zambales, Philippines. Iba is one of the 13 towns that make up the Zambales province. A total of 509 responses were gathered, based on the sampling size of at least 385, which was determined using Raosoft’s sample size calculator. Google Forms served as the principal instrumentation and data-gathering procedure, but paper questionnaires were also provided for those without Internet access.
Findings: This study found that digital payments significantly enhanced the convenience and ease of luxury consumption, particularly among employees in private enterprises. They appreciated the speed and simplicity of cashless transactions, eliminating the need to carry cash. Furthermore, these payment processes offered flexibility through options such as installment plans. For many, the seamless approach to making significant purchases hassle-free made digital payments appealing in today's fast-paced and technology-driven world.
Contribution to Theory, Policy, and Practice: It was important to strengthen security, enhance consumer education, and promote access to a safer, more responsible, cashless economy. The study recommended reinforcing security measures, enhancing consumer education, and ensuring broader access to foster a safer, more accountable, cashless economy.
A causalidade para a construção da ideia de Deus em Anaxágoras de Clazômenas e Sócrates
Authors: VERÇOSA GABRIEL RAMIRES 
Published: December 2024

Partindo do ponto de vista que o ser humano sempre esteve em contato com o sobrenatural, notamos que sua atitude, dentro das religiões antigas, busca estabelecer um vínculo com o princípio divino que deu origem ao universo. Porém, tais atitudes estãopermeadas de sentimentalismo e fantasias. A tentativa de investigar racionalmente a existência de Deus e construir uma noção simples de sua ideia, deve partir de algo seguro e natural ao ser humano – este é o modo que a filosofia irá trabalhar para elaborar uma teologia natural. Aplicando o princípio de causalidade, mesmo que de forma implícita, em Anaxágoras e Sócrates essa busca parece apontar para um princípio divino que gera e ordena todas as coisas.
A comprehensive analysis of immune characteristics and clinical prognosis in Asian COVID-19 patients infected with SARS-CoV-2 Omicron strain XBB sub-variants: a retrospective study of 450 cases
Authors: Li Fenge , Wang Yupeng , Jin Mengli , Li Hongli , Yan Jin , Hu Jiandong , Zhang Xianfeng , Wu Chunwa , Wei Luqing 
Published: December 2024

IntroductionThe pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has posed a severe threat to human health since December 2019. Immune characteristics and clinical symptoms manifested by COVID-19 patients of the most recent new strains have not been reported.Material and methodsWe retrospectively investigated 450 patients with laboratory-confirmed COVID-19 infection from December 2022 to January 2023. Clinical information and peripheral blood of the patients were obtained and analyzed for serum IL-6 levels and T cell sub-types. Post hoc analysis was performed to uncover immunological and involved COVID-19-associated pneumonia differences between patients with different underlying diseases and ages.ResultsThe median age of the patients was 75.5 years old. 60% of the patients were male and 40% were female. The most common symptoms were cough (344/450,76.4%), fever (317/450, 70.4%), expectoration (199/450, 44.2%) and wheeze (143/450, 31.8%). The mean hospital stay was 11.85 days (range: 1–57). 92% of the patients recovered in a month. The level of serum IL-6 was significantly higher in patients without underlying diseases compared with patients with hypertension, chronic obstructive pulmonary disease (COPD), cancer and diabetes (p < 0.001). Serum IL-6 level was significantly higher in patients who were 66–79 years old than that in patients aged 65 years and younger (p < 0.001). Peripheral CD8+T cell percentage was significantly higher in patients aged 65 years and younger than that in patients aged 80 years and older (p = 0.05). The mean involved ground-glass opacity area of the lung of all studied patients found by chest computed tomography (CT) at the time of initial onset of symptoms was 35.7%. Fifty-seven out of 132 (43.2%) patients who had assessable CT scans at 4–12 weeks after infection completely recovered with no chest CT abnormality. Involved ground-glass area of the lung of patients with diabetes or without underlying disease was significantly more severe than that in patients with COPD (p = 0.041 and p = 0.017, respectively). Involved ground-glass area of the lung of patients aged 80 years and older was significantly more severe than that in patients aged 65 years and younger (p = 0.031).Conclusions92% of COVID-19 patients infected with Omicron XBB sub-variants of SARS-CoV-2 can recover well in a month. Patients aged 80 years and older who have a lower lymphocyte percentage experienced more severe pneumonia than patients aged 65 years and younger having a higher lymphocyte percentage. Serum IL-6 level can be a recovery indicator for patients with COVID-19 infection.
The effect of cheese intake on osteoarthritis: a Mendelian randomization study
Authors: Wen Song , Huang Zehan , Zhang Bin , Huang Yuqing 
Published: December 2024

IntroductionOsteoarthritis (OA) is a debilitating chronic disease with a high prevalence, characterized by progressive degeneration of articular cartilage that leads to joint dysfunction, pain, and disability. Observational studies investigating the link between cheese intake and OA have yielded inconclusive results and may be susceptible to confounding.Material and methodsWe performed a two-sample Mendelian randomization (MR) investigation to evaluate the causal association between cheese intake and OA based on genome-wide association studies (GWAS). The primary analysis employed the inverse variance weighted (IVW) method, while complementary analyses were conducted using the weighted median, MR-Egger, and weighted mode methods. Moreover, we weighted each single nucleotide polymorphism’s (SNP) effect on OA by its effect on cheese intake and subsequently meta-analyzed these estimates utilizing a fixed-effects model to provide a summary effect estimate. To assess the robustness of the outcomes, we performed a sensitivity analysis.ResultsOur two-sample MR analysis revealed an inverse causal relationship between cheese intake and several types of OA, including self-reported OA (odds ratio (OR) = 0.96, 95% confidence interval (CI) = 0.94–0.97, p = 6.70 × 10–7), OA of the hip or knee (OR = 0.59, 95% CI = 0.48–0.72, p = 1.38 × 10–7), knee OA (OR = 0.52, 95% CI = 0.42–0.66, p = 4.11 × 10–8), and hip OA (OR = 0.72, 95% CI = 0.53–0.96, p = 0.0268). Additionally, the fixed-effects model also demonstrated a causal inverse association between cheese intake and OA, with a pooled meta-analysis OR of 0.95 (95% CI = 0.94–0.97, p < 0.0001).ConclusionsOur findings provided compelling genetic evidence of causal inverse associations between cheese intake and various types of OA, including self-reported OA, OA of the hip or knee, knee OA, and hip OA, which may enhance the efficacy of OA prevention by deepening our comprehension of the involved risk factors.
Causal associations of circulating inflammatory proteins with sepsis: a two-sample Mendelian randomization study
Authors: Ji Dandan , Ma Jiawei , Ma Jing , Wu Jia 
Published: December 2024

IntroductionSepsis arises from dysregulated inflammation in response to infection, precipitating organ dysfunction. Circulating inflammatory mediators likely contribute to sepsis pathogenesis, but their precise roles remain unclear. We aimed to evaluate potential causal impacts of inflammatory proteins on sepsis risk.Material and methodsWe performed a two-sample Mendelian randomization study evaluating causal associations for 91 inflammatory proteins with sepsis risk. Genetic instruments were derived from a published genome-wide association study of plasma proteins. Sepsis outcome data were obtained from the UK Biobank and FinnGen cohort. Inverse-variance weighted analysis was conducted along with several sensitivity analyses.ResultsThe analyses identified significant causal associations for several inflammatory proteins with sepsis risk. TRAIL exhibited a causal effect on increased overall sepsis risk (OR = 1.10, 95% CI: 1.03–1.17). CCL28 showed a causal link to higher 28-day sepsis mortality in critical care (OR = 3.32, 95% CI: 1.18–9.29). CCL4 demonstrated a causal association with increased 28-day sepsis mortality (OR = 1.81, 95% CI: 1.06–1.31). Meanwhile, beta-NGF was found to be causally protective for sepsis (OR = 0.77, 95% CI: 0.60–0.99), and TNFB also showed a causally protective effect (OR = 0.95, 95% CI: 0.91–1.00).ConclusionsOur study elucidates roles of inflammatory mediators in sepsis pathogenesis. The identified proteins may serve as biomarkers or therapeutic targets. TRAIL signaling inhibition may hold promise for future clinical translation given its causal links to increased sepsis risk and mortality. CCL28 and CCL4 also represent potential immunological drivers of sepsis mortality worthy of further investigation. Meanwhile, the neurotrophins beta-NGF and TNFB emerged as having protective effects in sepsis that could be therapeutically augmented. Further experimental validation is warranted to confirm the observed causal relationships. Our findings provide targets for future mechanistic and clinical examination to impact patient prognosis.
Identifying core genes in sepsis by LASSO regression and SVM-RFE algorithm
Authors: Luo Linlin , Yu Jie 
Published: December 2024

IntroductionSepsis is a major disease in intensive care units (ICU), with high morbidity and mortality. However, the core genes associated with the sepsis diagnosis remain unclear.Material and methodsBy merging five datasets, gene expression profiles were obtained: GSE28750, GSE57065, GSE64457, GSE65682 and GSE95233. Differentially expressed genes (DEGs) were identified using the Limma package in R. To examine the enriched functions, both Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) were employed. Subsequently, the protein-protein interaction network (PPI) was constructed, and module analysis was carried out using STRING and Cytoscape. Furthermore, core genes were identified using support vector machine recursive feature elimination (SVM-RFE) analysis and the least absolute shrinkage and selection operator (LASSO) model. To verify the diagnostic significance of these essential genes, we conducted an analysis of the receiver operating characteristic curve (ROC).ResultsWe analyzed 230 DEGs, consisting of 183 upregulated DEGs and 47 downregulated DEGs. The GO and KEGG analyses revealed that the DEGs were enriched in immune-related pathways and functions. The DEGs formed a PPI network consisting of 180 protein nodes and 351 interaction edges. Ultimately, we identified the five critical core genes (C3AR1, CHPT1, RAB32, SLC22A4, and SRPK1) common between both algorithms. The analysis of the ROC curve demonstrated that the AUC values for the five fundamental genes were as follows: 0.881, 0.876, 0.946, 0.927, and 0.931, respectively.ConclusionsThe five core genes screened in this study will help us to interpret the underlying molecular mechanism of sepsis and hopefully become potential diagnostic targets.
L’expression artistique par la voix et les gestes
Authors: Schweitzer Claudia 
Published: December 2024

L'article propose un regard sur la théorisation et sur les instructions pour la mise en pratique de ce que les auteurs français de l'âge classique appellent actio : la modulation de la voix et des gestes à des fins expressives. Partant des descriptions des définitions établies par les philosophes de l'époque (école cartésienne et Lumières sur les effets d'un sentiment éprouvé et transmis, l'étude proposée concerne la dans différents domaines artistiques (acteurs et démarche chanteurs, en passant par la référence aux peintres) pour donner des règles pratiques afin de transformer ces analyses en une expression artistique qui plaît, qui convainc, qui touche et notamment qui émeut.
The Impact of Community Health Volunteers’ Service Delivery on Nutrition Outcomes of Households with Children 6-59 Months in Alego Usonga, Siaya County, Kenya
Authors: Odiwuor Amos , Sigot Asenath , Mutuli Lucy 
Published: December 2024

Community Health Volunteers (CHVs) are used in nutrition service delivery and realizing Universal Health Coverage. Nevertheless, poor nutrition outcomes still exist in households under the care of CHVs, resulting in high rates of malnutrition and deaths. Guided by the Health Belief Model (HBM) the researcher established the relationship between the service delivery of CHVs and the nutrition outcomes of households with children aged 6-59 months in Alego Usonga Sub-County, Siaya County, Kenya. A cross-sectional study design was used. The sample size was determined using Krejcie and Morgan's formula to arrive at 353 participants. The researcher then used purposive, multi-stage, and systematic sampling strategies to reach the participants. Data was collected using structured questionnaires. The target population was households with children 6-59 months in Alego Usonga, Siaya County. SPSS software was used to analyze data, after that, the relationships were tested using Fisher’s Exact Test. Results: significant association between frequency of household visitation by CHVs and MDD, growth monitoring and promotion clinic attendance, deworming in the past six months, and availability of kitchen gardens in the households (p-values<0.05, FET); significant association between referral for immunization and FIC at 11 months (p-value 0.022, FET), referral for growth monitoring and promotion, and the number of children attending growth monitoring and promotion clinics (p-value 0.002, FET); significant association between counseling on complementary feeding and other foods consumed by children 6-23 months other than breast milk (p-value 0.047, FET), counseling on complementary feeding and MDD and MMF (p-values 0.014 & 0.003, respectively, FET), counseling on growth monitoring and promotion and attendance of growth monitoring and promotion clinics (p-value 0.001, FET), and counseling on the importance of kitchen garden and availability of kitchen gardens in the households (p-value 0.000, FET). Therefore, a significant relationship exists between household visitations, referrals, follow-ups, and counseling services conducted by CHVs, and the nutrition outcomes of households with children aged 6-59 months. Following these findings, the researcher recommends that the government continue supporting the CHVs by providing timely motivation and adequate resources. However, other experimental study designs with stronger statistical significance should be deployed to directly evaluate the CHVs’ service delivery and nutrition outcomes at the household level.
CHATGPT COMO FERRAMENTA EDUCACIONAL: UMA ANÁLISE UTILIZANDO LÓGICA FUZZY
Authors: Sishan Fernanda Caroline Santos , Gonçalves Benevaldo Pereira 
Published: December 2024

Este artigo tem como objetivo analisar a relação entre o uso do ChatGPT e o processo formativo de graduandos de Engenharia de Software do Instituto Federal de Educação, Ciência e Tecnologia do Amazonas - Campus Manaus Zona Leste. Identificando quais são os benefícios e os malefícios do uso da plataforma no contexto educacional. Para isso, foi utilizado como método um estudo de caso, com a aplicação de um questionário composto por questões fechadas. A pesquisa foi realizada com os estudantes finalistas, ou seja, do oitavo período de Engenharia de Software, visto que esses graduandos possuem mais tempo de experiencia no curso do que as demais turmas. Para análise das respostas dos participantes foi utilizada a lógica fuzzy, por ela ser mais maleável do que a tradicional lógica booleana e assemelhasse mais as perspectivas humanas. Os resultados deste estudo indicam que embora os discentes de engenharia de software utilizem frequentemente a plataforma ChatGPT para pesquisas rápidas, ainda possuem certo receio e preocupações, principalmente com o risco a dependência excessiva e risco de plágio ao utilizar para realizar atividades acadêmicas.
Increasing Student Activeness Using The Cooperative Model TGT IPAS Class IV SDN Tambak Wedi 508
Authors: Widiastya Dita Widiastya , Dita Rahmania Widiastya  , Devina Oviana Dwi Agustin  , Silvyulla Puspita Ambarsari  , Agung Setyawan  , Tehseen Mazhar  
Published: December 2024

This research is motivated by observational data that shows students' learning activity in IPAS material is very low. To respond to that, the researcher conducted a classroom action research aimed at improving students' learning activity. The objectives to be achieved in this research include: (1) To determine the improvement of students' engagement in learning through the use of lecture method, (2) To determine the improvement of students' engagement in the learning process through the use of cooperative learning model, specifically Teams Games Tournament (TGT). This research is a classroom action research. This research was conducted in class IVB with a total of 32 students, consisting of 17 male students and 15 female students. The research was conducted in 2 cycles, and the results showed an improvement in effectiveness in the second cycle. The change occurred because in the second cycle, students were more engaged in working together with their group, so there was less opportunity to discuss with other groups. This research measures several student learning skills, namely: questioning skills, answering skills, discussing skills, and group learning skills. The research findings show improvement in each domain in each cycle.The selection of this learning model is highly suitable and can enhance students' engagement in learning because in this learning model, students are not just passive listeners during the lesson, but they actively participate, think, learn, and compete among groups. This makes students challenged to win the competition and become active in learning.
Micropulse laser cyclophotocoagulation in the treatment of secondary glaucoma in patients with post-burn and terminal dystrophic corneal leukoma as a stage of preparation for keratoprosthesis surgery
Authors: Sokolovskaya T. V. , Golovin A. V. , Starostina A. V. , Sholokhova V. R. , Shishkova L. A. 
Published: December 2024

PURPOSE. To evaluate the effectiveness of micropulse laser cyclophotocoagulation (mCPC) in patients with secondary glaucoma associated with post-burn and terminal dystrophic corneal leukomas.METHODS. Twelve patients (12 eyes) with corneal leukomas and secondary glaucoma underwent mCPC. The mean age of the patients was 44±6.5 years, including 8 men and 4 women. All patients exhibited elevated intraocular pressure (IOP), ranging from Tpalp "+" to Tpalp "++," despite being on maximum combination hypotensive therapy. Visual acuity for all patients was 1/∞ light perception with correct projection (proectia lucis certa).RESULTS. On the first postoperative day, IOP was reduced to Tpalp "+" in 4 patients and to Tpalp "N" in 8 patients. Hypotensive therapy was continued based on individual indications throughout the observation period. By day 7, IOP had decreased to Tpalp "N" in all patients and remained stable throughout the follow-up period. Visual acuity in all cases remained unchanged from the preoperative level. Ultrasound biomicroscopy (UBM) revealed that the mean ciliary body thickness (CBT) before surgery was 0.56±0.11 mm. On the first postoperative day, CBT increased by an average of 20.1% due to pronounced edema caused by hydration from the inflammatory response, with a gradual return to baseline by the 1-month follow-up. At 6 months, no statistically significant difference in CBT from the preoperative thickness was observed, with a mean CBT of 0.50±0.12 mm.CONCLUSIONS. Micropulse cyclophotocoagulation can be an effective treatment for secondary glaucoma in patients with post-burn and terminal dystrophic corneal leukomas. This technique reduces the risk of intraoperative and postoperative complications due to its non-invasive nature and low surgical trauma. The procedure can be repeated if IOP increases, and gentle laser parameters can help preserve visual potential.
USO DE RECURSOS EDUCATIVOS DIGITALES PARA LA ENSEÑANZA DE LA QUÍMICA
Authors: Miranda Monar Erika Elba , Cajamarca Alvarado Martha Elizabeth 
Published: December 2024

En el presente trabajo las autoras dejan un estudio referativo sobre el uso de los recursos digitales en la enseñanza de Química, buscando profundizar en un tema que si bien no es nuevo permite abordar una temática de suma importancia en la actualidad, la enseñanza de una disciplina escolar cómo la Química siempre deberá estar acompañada de todas las herramientas que desde el punto de vista de las ciencias y la Didáctica sean necesarias para un aprendizaje eficaz, precisamente el trabajo buscar dejar plasmado cuales son algunas de estas herramientas que permiten este tipo de desarrollo.