bluuebunny/crossref_metadata_2025_split huggingface dataset:
Centenario de la Constitución de Weimar
Authors: Hirschmann Pablo 
Published: December 2020

El 11 de agosto de 2019 se cumplieron cien años de la aprobación de la Constitución de Weimar, primera constitución democrática de Alemania. Su conmemoración generalmente evoca al régimen que precedió al Tercer Reich, responsabilizándolo de su génesis, o, en menor medida, recuerda uno de los primeros hitos de la consagración positiva del Constitucionalismo Social. En este trabajo -recorriendo brevemente los antecedentes de esta constitución alemana, su proceso constituyente, sus contenidos más innovadores, algunas de las causas de su fracaso y sus proyecciones sobre otras constituciones aprobadas posteriormente- se pretende rememorar un intento optimista, claramente modernizador de la sociedad y de la política, impulsado por fuerzas y vías democráticas respetuosas del pluralismo y de la dignidad de la persona; en un contexto desolador y tenebroso que la incomprensión incrementó -día tras día- arrastrando al abismo a algunos culpables y a muchos inocentes. El 11 de agosto de 2019 se cumplieron cien años de la aprobación de la Constitución de Weimar, primera constitución democrática de Alemania. Su conmemoración generalmente evoca al régimen que precedió al Tercer Reich, responsabilizándolo de su génesis, o, en menor medida, recuerda uno de los primeros hitos de la consagración positiva del Constitucionalismo Social. En este trabajo -recorriendo brevemente los antecedentes de esta constitución alemana, su proceso constituyente, sus contenidos más innovadores, algunas de las causas de su fracaso y sus proyecciones sobre otras constituciones aprobadas posteriormente- se pretende rememorar un intento optimista, claramente modernizador de la sociedad y de la política, impulsado por fuerzas y vías democráticas respetuosas del pluralismo y de la dignidad de la persona; en un contexto desolador y tenebroso que la incomprensión incrementó -día tras día- arrastrando al abismo a algunos culpables y a muchos inocentes.El 11 de agosto de 2019 se cumplieron cien años de la aprobación de la Constitución de Weimar, primera constitución democrática de Alemania. Su conmemoración generalmente evoca al régimen que precedió al Tercer Reich, responsabilizándolo de su génesis, o, en menor medida, recuerda uno de los primeros hitos de la consagración positiva del Constitucionalismo Social. En este trabajo -recorriendo brevemente los antecedentes de esta constitución alemana, su proceso constituyente, sus contenidos más innovadores, algunas de las causas de su fracaso y sus proyecciones sobre otras constituciones aprobadas posteriormente- se pretende rememorar un intento optimista, claramente modernizador de la sociedad y de la política, impulsado por fuerzas y vías democráticas respetuosas del pluralismo y de la dignidad de la persona; en un contexto desolador y tenebroso que la incomprensión incrementó -día tras día- arrastrando al abismo a algunos culpables y a muchos inocentes.
LEFT SUBCLAVIAN ARTERY RUPTURE DUE TO BLUNT THORACIC TRAUMA: A CASE REPORT
Authors: Habibie Yopie Afriandi , Wuryantoro Ign 
Published: December 2020

Abstract. Blunt thoracic trauma highest incidence is in adult, 20% to 50 % of the trauma cause death. Injuries to the vascular structures of the thoracic outlet, especially left subclavian artery, are rare and typically accompanied by massive hemorrhage. Close observation of vital sign and serial chest x-ray are very important. We describe an unusual presentation of a patient who suffered traumatic rupture ofleft subclavian artery. No clinical presentation of supraclavicular hematoma, unilateral absence of radial artery pulse and mediastinal widening in chest x-ray was found, but there is a massive hemothorax. Left posterolateral thoracotomy was performed, the source of bleeding was found in the apex of the lung, suspected a rupture of the left subclavian artery. The procedure continued with median sternotomy extended to left supraclavicular incision, a rupture was found in the left subclavian artery, 1,5 cm proximal to aortic arch. Primary repair was done with a good result. Key Words : Blunt thoracic trauma, massive hemothorax, left subclavian artery rupture
TUBERKULOSIS INTRAOKULAR
Authors: Astari Prilly 
Published: December 2020

Abstrak. Tuberkulosis (TB) adalah suatu penyakit menular yang disebabkan oleh kuman dari kelompok Mycobacterium yaitu Mycobacterium tuberculosis. TB paling banyak menyerang organ paru-paru, namun sekitar 20% dapat melibatkan organ tubuh lainnya, termasuk mata. Infeksi oleh Mycobacterium tuberculosis pada struktur di dalam mata dinamakan TB intraokular. Terdapat beberapa kontroversi terkait terminologi, diagnosis, dan terapi yang mengakibatkan prevalensi TB intraokular sangat beragam, pemilihan tes diagnostik yang berbeda – beda, serta durasi terapi Obat Anti Tuberkulosis (OAT) yang berbeda – beda. Kata kunci: imunologi, infeksi, koroiditis, tuberkulosis, uveitis Abstract. Tuberculosis (TB) is an infectious disease caused by the bacteria, Mycobacterium tuberculosis. TB typically affects the lungs, but it can also affect other organs, including the eyes. Infection by Mycobacterium tuberculosis inside the eye is called intraocular TB. There are several controversies related to the terminology, diagnosis, and therapy that result in varying prevalence of intraocular TB, different selection of diagnostic tests, and different duration of Anti-TB therapies. Keywords: choroiditis, immunology, infection, tuberculosis, uveitis
THE ROLE OF OCULAR BLOOD FLOW IN THE PATHOGENESIS OF GLAUCOMA
Authors: Primitasari Yulia , Komaratih Evelyn 
Published: December 2020

Abstract. Glaucoma is currently the second leading cause of blindness worldwide and the prevalence is expected to increase. Despite lowering of IOP, vascular risk factors, genetics, and other systemic conditions could progress the glaucoma damage. Ocular blood flow has emerged as an increasingly prevalent glaucoma risk factor in large population-based trials. Abnormal perfusion and the subsequent ischemia of the ONH play a major role in the glaucomatous damage. Ocular Blood flow is unstable if IOP fluctuates on a high enough or blood pressure on a low enough level to exceed temporarily the autoregulation capacity. IOP fluctuation is also related to both an increase in scotomas and an increase in diffuse visual fields damage. OBF is unstable if autoregulation itself is disturbed. In glaucoma the response of retinal and optic nerve head blood flow to flicker stimulation is reduced. Primary vascular dysregulation appears to be associated with abnormal retinal neurovascular coupling, because vasospastic subjects show a reduced response to flicker stimulation.Keywords: ocular blood flow, glaucoma
HUBUNGAN KEPADATAN DERMATOPHAGOIDES SPP. DENGAN FREKUENSI SERANGAN ASMA PADA PENDERITA ASMA DI RS PARU JEMBER
Authors: Rahmadatu Denaneer , Sulistyaningsih Erma , Agustina Dini 
Published: December 2020

Abstrak. Asma merupakan gangguan inflamasi kronik saluran napas yang bersifat hiperesponsif yang ditandai adanya gejala episodik berulang berupa mengi, sesak napas, dada terasa berat, dan batuk, terutama pada malam hari atau dini hari. Sekitar 50-80% asma disebabkan oleh tungau debu rumah (TDR), khususnya Dermatophagoides pteronyssinus dan Dermatophagoides farinae. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara kepadatan Dermatophagoides spp. pada debu rumah dengan frekuensi serangan asma pada penderita asma di RS Paru Jember. Penelitian ini merupakan penelitian analitik observasional dengan desain penelitian cross-sectional. Sampel penelitian ini yaitu 30 penderita asma di RS Paru Jember yang diambil menggunakan teknik simple random sampling sesuai dengan kriteria inklusi dan eksklusi. Peneliti melakukan interview mengenai frekuensi serangan asma dalam tiga bulan terakhir, mengambil debu dari ruang tamu dan ruang tidur pada rumah penderita asma, dan mengidentifikasi tungau debu rumah (TDR) yang ditemukan pada debu. Hasil uji Pearson mendapatkan nilai p=0,011 dan nilai r=0,475 sehingga dapat disimpulkan bahwa terdapat hubungan bermakna antara kepadatan Dermatophagoides spp. dengan frekuensi serangan asma dengan kekuatan korelasi sedang pada penderita asma di RS Paru Jember. Kata Kunci: Dermatophagoides spp., Tungau Debu Rumah (TDR), Asma Abstract. Asthma is a chronic inflammatory disorder of the respiratory system characterized by recurrent episodes of wheezing, shortness of breath, chest tightness, and cough, particularly at night or early morning. About 50-80% of asthma is caused by house dust mite (HDM), especially Dermatophagoides pteronyssinus and Dermatophagoides farinae. This study aimed to investigate the correlation between the density of Dermatophagoides spp. and the frequency of asthma attacks in asthmatic patients at Jember Pulmonary Hospital. This study was an observational analytic study with a cross-sectional design. Respondents were 30 asthmatic patients at Jember Pulmonary Hospital matched with inclusion and exclusion criteria and chose by simple random sampling. Respondents were interviewed about the frequency of asthma attacks in the last three month,s and the hose dust from the living and sleeping rooms were collected for identification of house dust mites (HDM). The pearson test showed a value of p=0.011 and r=0.475. It can be concluded that there is a significant correlation with the moderate strenght between the density of Dermatophagoides spp. and the frequency of asthma attacks in the asthmatic patient at Jember Pulmonary Hospital. Keywords: Dermatophagoides spp., House Dust Mites (HDM), Asthma
Gambaran obesitas pada pasien stroke akut di Rumah Sakit Umum DaerahArifin Achmad Provinsi Riau periode Januari-Desember 2019
Authors: Fuadi Muhammad Ikhwan , Nugraha Dimas Pramita , Bebasari Eka 
Published: December 2020

Abstrak. Stroke adalah penyakit akibat gangguan peredaran darah otak yang dipengaruhi oleh banyak faktor risiko. Stroke merupakan penyebab utama disabilitas. Stroke secara umum diklasifikasikan menjadi stroke iskemik atau stroke non hemoragik dan stroke hemoragik. Salah satu faktor risiko terjadinya stroke adalah obesitas. Tujuan penelitian ini adalah untuk mengetahui gambaran obesitas pada pasien stroke akut di RSUD Arifin Achmad Provinsi Riau Periode Januari–Desember 2019. Desain penelitian yang digunakan adalah penelitian deskriptif dengan rancangan cross sectional menggunakan data sekunder rekam medis pasien stroke akut di RSUD Arifin Achmad Provinsi Riau Periode Januari-Desember 2019 dengan jumlah sampel sebanyak 115 kasus. Hasil penelitian menunjukkan stroke banyak terjadi pada usia terbanyak terjadi pada rentang usia 51-65 sebanyak 60 kasus (52,2%). Jenis kelamin terbanyak yaitu laki-laki sebanyak 67 kasus (58,3%). Jenis stroke terbanyak adalah stroke hemoragik yaitu 62 kasus (53,9%). Terdapat 65 kasus (56,5%) pasien obesitas, sebanyak 34 kasus (52,3%) adalah stroke hemoragik. Kesimpulan dari penelitian ini adalah obesitas lebih banyak terjadi pada stroke hemoragik dibanding stroke iskemik.Kata kunci: obesitas, strokeAbstract. Stroke is a disease caused by the interrupted of blood supply to the brain which can be influenced by several risk factors. Stroke is a major cause of disability. Stroke is generally classified as ischemic or non-hemorrhagic and hemorrhagic stroke. One of those risk factors of stroke is obesity. The aim of this study was to describe obesity in acute stroke patients at Arifin Achmad Regional Hospital of Riau Province in January- December 2019. This was a descriptive study design with cross sectional study method while using medical records of the acute stroke patient’s at Arifin Achmad Regional Hospital of Riau Province in January to December 2019. There were 115 cases fulfilled the criteria. The results show that the majority happened within 51-65 years age group with 60 cases (52,2%) and frequently in male as much as 67 cases (58,3%). Most patients had hemorrhagic stroke with 62 cases (53,9%). In 65 cases (56,5%) of obese patients cases, 34 cases (52,3%) were hemorrhagic strokes. The conclusion of this study is that obesity more commonly occurs in hemorrhagic stroke types compared to the ischemic.Keywords: acute stroke, obesity
SKENARIO PENGELOLAAN KEPESISIRAN BERKELANJUTAN KABUPATEN BUTON SELATAN, PROVINSI SULAWESI TENGGARA
Authors: Alisyukur La Ode , Sunarto Sunarto , Aris Marfai Muh 
Published: December 2020

The coastal zone of South Buton Regency consists of unique ecosystems and abundant natural resources, but facing problems, mainly in terms of conflict between economic needs and ecological aspects. This study aims to set up scenarios for sustainable coastal zone management (SCZM) in South Buton Regency that are synergistic and benefit all stakeholders, without disregarding the principals of ecological conservation. Data were collected by interviews and field observations and were analyzed using prospective analysis method. Comprehensive analyisis were performed encompassing the effects and interactions of key components of the successfulness of the SCZM in South Buton based on the stakeholders desires. Three environmental management scenarios were assessed, namely: the conservative-pessimistic scenario, in which refinements for the key components are at minimum levels, the moderate-optimistic scenario, in which refinements for the key components are about 50%, and the progressive-optimistic scenario, in which all the key components are addressed for refinements. Results of the prospective analysis show that the moderate-optimistic scenario was the most appropriate scheme to be implemented for the sustainable coastal zone management in South Buton Regency, follows by progressive-optimistic and conservative-pessimistic scenarios, respectively.
Keywords: Coastal zone; Key components; Prospective analysis; Environmental management
STATUS MUTU AIR SUNGAI AYUNG BERDASARKAN DATA PEMANTAUAN KUALITAS AIR TAHUN 2014-2018
Authors: Sara Wijana I Made , Ernawati Ni Made , As-syakur Abd Rahman 
Published: December 2020

It is very important to know the status of river water quality, in order to determine the direction of resource management which is decreasing in quality according to its allocation. Analysis of the status of the water quality of the Ayung River in Bali Province using secondary data in the form of data on illness results from 2014 to 2018. The number of parameters applied to the fire is 16 parameters with class II water quality standards referring to attachment XII of Bali Governor Regulation No. 16 of 2016 concerning Environmental Quality Standards and Environmental Damage Standard Criteria. The analysis used the Storetic Method (Decree of the Minister of Environment Number 115 of 2003). The results of the analysis show that the status of Ayung River water is at very good, good and moderate levels. The status of the Ayung River's air quality tends to decline from year to year and from upstream to downstream. Status determining parameters are: BOD5, phosphate, phenol, detergent and sulfide.
Key words: water quality status; ayung river; storet.
Keseimbangan mekanisme fotosintesis dan carnivory pada tumbuhan kantung semar: suatu kajian pustaka
Authors: Ubaidillah Syafiq , Mukarrahman Luluk , Perwitasari Dian A. G. , Rohimah Siti , Wardani Fefi E , Su'udi Mukhamad 
Published: December 2020

Kantung semar (Nepenthes sp.) merupakan tanaman karnivora yang mampu membentuk struktur kantung ketika nutrisi dalam lingkungan tidak mencukupi untuk mendukung pertumbuhan dan perkembangannya. Tujuan penyusunan artikel ini adalah untuk mengkaji karakterisitik morfologi dan fisiologi Nepenthes khususnya karakter fotosintesis yang dimiliki, serta mekanisme carnivory dengan beberapa enzim pencernaan yang dihasilkan. Berdasarkan kajian yang telah dilakukan diketahui bahwa Nepenthes mampu melakukan mekanisme carnivory dan fotosintesis secara bersamaan. Tanaman ini mendapatkan N organik dan N inorganik melalui kedua mekanisme tersebut. Berdasarkan struktur anatomi daun, tanaman ini diduga sebagai tanaman C3 tetapi memiliki laju rata-rata fotosintesis lebih rendah dari tanaman C3 non-karnivora. Mekanisme carnivory pada Nepenthes dibantu oleh beberapa enzim diantaranya glukanase, kitinase, protease, nuklease, phospatase, lipase dan peroxidase.
Kata kunci: C3, Nepenthes, Carnivory
Checklist of gastropoda from Lombok Island and its satellite islands
Authors: Mujiono Nova 
Published: December 2020

Lombok, an island that lies in the Lesser Sunda Islands, is popular for the tourist destination. One attempt to promote tourism is through the biodiversity of its fauna. This study aims are to summarized the diversity of gastropoda and made a checklist to make it easier studied. Museum collections and fifteen works of literature were used as the data source. A total of 74 families and 292 species of gastropoda were documented from 29 locations. Twenty-one species are new records for Lombok Island. About 29% of them have their representation in the museum collections. The list dominated by marine (65%), following by terrestrial (15%), mangrove (6%), and freshwater species (5%). The most diverse family, Neritidae, which occupies wider habitat is represented by nine percent. Littoraria scabra is the most widely distributed species which occurs in 12 locations. The five most diverse locations were marine habitats which popular for tourism destinations. This study contributes to the development of marine ecotourism.
AKTIVITAS ANTIHIPERPIGMENTASI LIKOPEN SECARA IN SILICO
Authors: Widyastuti M. D. , Noviyanti N. K. M. , Sanjaya I K. N. S. , Susanti N. M. P. 
Published: December 2020

Hiperpigmentasi disebabkan oleh terakumulasinya melanin yang berlebihan pada kulit sehingga terjadi penggelapan kulit. Hiperpigmentasi ini salah satu penyebab orang kurang percaya diri, sehingga produk kosmetik dipasaran menawarkan solusi antihiperpigmentasi. Senyawa yang umum digunakan pada produk antihiperpigmentasi adalah hidrokuinon Permasalahan penggunaan hidrokuinon terletak pada efek samping yang ditimbulkan yaitu okronosis, genotoksisitas, dan karsinogenik. Tujuan penelitian ini untuk mengetahui potensi likopen sebagai antihiperpigmentasi secara in silico dengan mekanisme penghambatan tirosinase dibandingkan dengan hidrokuinon. Metode yang digunakan adalah molecular docing. Analisis data dilakukan dengan membandingkan energi ikatan yang diperoleh dari likopen dan hidroquinone yang di-docking-kan dengan tirosinase. Energi ikatan dari kedua senyawa tersebut dengan tirosinase secara berturut-turut adalah -5,18 dan -4,22. Nilai energi ikatan tirosinase lebih rendah dibandingkan dengan hidrokuinon. Perbandingan energi ikatan dari likopen dan hidroquinone menunjukkan bahwa likopen merupakan senyawa yang memiliki potensi sebagai inhibitor tirosinase secara in silico dengan aktivitas yang lebih tinggi dibandingkan dengan hidrokuinon.

Kata kunci: Hiperpigmentasi, Hidrokuinon, Likopen, In Silico
PENGARUH KONSENTRASI GELLING AGENT TERHADAP DIFUSI SEDIAAN GEL VITAMIN C DENGAN METODE SEL DIFUSI FRANZ
Authors: Meiantari N. K. A. , Deviyanti I. A. S. , Ari N. K. N. A. , Abimanyu M. D. , Dewi N. P. D. K. , Sriani N. K. , Arwanawati N. N. S. M. 
Published: December 2020

Difusi didefinisikan sebagai suatu proses perpindahan molekul karena adanya perbedaan kosentrasi molekul melalui suatu membran semipermeable. Uji difusi sediaan gel vitamin C bertujuan untuk mengetahui pengaruh dari jumlah gelling agent terhadap difusi vitamin C. Uji difusi sediaan vitamin gel dilakukan dengan menggunakan sel difusi Franz serta kadar dianalisis dengan metode titrasi iodometri. Bedasarkan hasil diperoleh bahwa dalam waktu 5,10, 20 dan 30 menit, jumlah terdifusi sediaan gel vitamin C 1% berturut-turut yaitu 378,5 mg; 108,71 mg; 223,33 mg; 3442,13 mg sementara untuk sampel 2% yaitu 269 mg; 431,64 mg; 475,07 mg; 574,11 mg dan untuk sampel 3% yaitu 543 mg; 594,08 mg; 646,27 mg; dan 700,77 mg. Bedasarkan hal tersebut pelepasan dari sediaan gel vitamin C sebanding dengan waktu yang diberikan, semakin lama waktu yang diberikan maka pelepasan sedian gel vitamin C semakin meningkat. Dapat disimpulkan, pengaruh dari jumlah gelling agent terhadap difusi sediaan gel vitamin C adalah semakin tinggi konsentrasi gelling agent maka semakin meningkat kadar pada kompartemen reseptor yang diperoleh.
Kata kunci : difusi, kosentrasi, gelling agent, gel vitamin C
Strategi Pengembangan Desa Pasrujambe Pasca Ditetapkan Sebagai Desa Wisata di Kabupaten Lumajang
Authors: Cahyono Albhet Raphow Rudolf , Narottama Nararya 
Published: December 2020

Reffering to the regulation of the Lumajang Regent number 79 of 2014 about the spread of tourist destinasion, each sub-distric must has a tourism village. So with this regulation Lumajang has 21 tourism village and one of them is Pasrujambe Village. Pasrujambe Village was designated as a tourism village based on the delibration of all village in Pasrujambe Sub-distric, because the village has potentials of tourism like waterfalls, agriculturan land, grebeg nusantara event etc. But now the tourism potentials has not been maximized for tourism activities, so until now Pasrujambe village has not many tourist. The tourism potentials in the village has the oppotunity to be developed to become a tourist activity like something to do, something to see and something to buy. So to achive this develompent requires a strategies based on the avilable potentials and this reasearch does it. The development srategies fromulated iis expected to have an impact such as increased tourist visits, increased local community pasticipation and optimalization tourism potential in the village. The data used in this research are primary and secondary. In this reseacrh observation, interview and literature studies are used to collect data in the reseach location. Descriptive qualiataif and SWOT analysis were used to analyze the data in this research.This research found that potentials of Pasrujambe Village is devided into three categories namely natural-based, culture-based, and artifical human-based. The strategies were devided into four categories are SO strategy with five strategies formulated, WO strategy with four strategies formulated, ST strategy with four strategies formulated, and WT strategy with three strategies formulate.

Keywords: Pasrujambe Tourism Village, Tourism Village, Develompmet Strategy
Siliconosis: an unknown entity in aesthetic breast surgery
Authors: Roszpopa Jaroszlav , Ahmad Zeeshan 
Published: December 2020

Background:
Siliconosis was first described in the late 1980s and it is still remaining as a rare condition and mainly as a diagnosis of exclusion after breast cancer investigation. There are only limited cases reported and published with even smaller amount related to the breast implants (31 studies and 8 related to breast implants found in PubMed search in December 2019).

Case presentation:
Authors present the case of siliconosis secondary to bilateral cosmetic breast augmentation performed back in 1989. The patient was troubled with a myriad of complications and underwent an exchange of implants with Trilucent™ implants in 1997 and their subsequent removal in 1998. Later, they underwent bilateral mastopexy and is currently free of implants. Ever-since the first operation patient complained of pain, localized tenderness, swelling, axillary fullness, paraesthesia and partial paralysis in her upper limbs amongst other symptoms. Objective investigations including plain radiographs, USS, CT, MRI, nerve conduction studies, rheumatological screen yielded essentially negative results. Thoroughly investigation for breast cancer was conducted, including several operations and biopsies of axillary swellings with confirming reactive lymphadenopathy. A working diagnosis of siliconosis has been made and the patient was treated expectantly.

Conclusion:
This case should remind our colleagues of the ethical and professional responsibilities we have toward our patients in explaining all the potential risks involved in breast augmentation and also to keep an open mind when meeting patients complaining of systemic symptoms post breast augmentation.