bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterising the Bushe-Poladpur Contact across the Western Deccan Traps and Implications for Mapping the K-Pg Boundary?
Authors: Patil Shiva Kumar , Gadpallu Purva , Monteiro Aristle , Sepahi Mohammad Noor , Duraiswami Raymond A. 
Published: March 2020

Abstract
The Bushe-Poladpur contact is one of the most important stratigraphic boundary separating the middle Lonavala Sub-group from upper Wai Sub-group in the Western Deccan Traps. In this paper, physical volcanology textural and petrochemical finger printing, crystal size distribution and shape preferred orientation studies (SPO) is integrated with paleomagnetic and AMS studies to correlate lavas across five localities transcending the Bushe-Poladpur boundary, south of Pune city. The flows belonging to the Bushe Formation are highly inflated, compound pahoehoe lavas, with plagioclase-olivine-phyric, coarse grained diktytaxitic textures. The flows belonging to the Poladpur Formation are transitional between pahoehoe and aa (rubbly pahoehoe lavas), with or without multi-tiered entablature showing fine-grained, olivine-phyric glassy textures. CSD studies indicate that the Bushe lavas have lower plagioclase crystals per unit area (1.11x10-4/μm2), low average effective nucleation rates (2.60x 10-12/μm3s) and high average effective growth rates (1.22x10-5μm2/s) for intact crust time than the Poladpur lavas that have higher plagioclase crystals per unit area (8.31x10-4/μm2), high average effective nucleation rates (3.46x10-11/μm3s) and lower average effective growth rates (2.24x10-6μm2/s) akin to their emplacement dynamics and cooling histories. There is a stark contrast in the magnetic susceptibilities (Bushe- 24759.8 x 10-6 SI; Poladpur-29178.02 x10-6 SI) across the Bushe-Poladpur contact. There is a general similarity between the SPO of the primary silicates (plagioclase) to the AMS derived directions. The divergence in AMS directions across the Bushe-Poladpur contact in the study area can be attributed to complex interplay of local paleotopography and slope, lava flow field dynamics, inflation and inversion of topography, style and emplacement mechanism of flow units. Generalisations and over simplifications of delineating lavas and deciphering their flow direction on a single criteria (tool) or single ghat (road section), outcrop or sample will have disastrous consequences while mapping large and complex lava flow fields. Thus, a multi-disciplinary approach needs to be the norm for characterising, correlating and mapping lavas across formations that transcend the K-Pg boundary in highly dissected ancient continental flood basalt province like the Deccan Traps.
Petrography and Clay Mineralogical Study of the Siwalik Group of Rocks Exposed along Pasighat-Mariyang Road Section, East Siang District, Arunachal Pradesh, Northeast India
Authors: Chutia Ananya , Taye Chaitra Dhar , Daimari Jagriti , Chutia Debasish 
Published: March 2020

Abstract
The Neogene (Mio-Pliocene) molassic sediments occur as a linear belt along the foot hills of Arunachal Pradesh, are designated as the Siwalik Group. Petrography, heavy mineral and clay mineralogical characteristics of these rocks exposed along Pasighat-Mariyang road section, East Siang district, Arunachal Pradesh, India is presented here. These massive and well bedded rocks are detached from alluvium by HFT and remarkably from Yinkiong Group of rocks by MBT. The present study reveals the presence of lower as well as middle-upper Siwalik in the study area. Petrographic study of the sandstones has shown that these rocks are mainly sub-arkose and sub-lith-arenite with lithic and feldspathic greywacke in subordinate amount, which are medium to coarse grained and composed mainly of quartz, feldspar, mica and rock fragments as their detrital constituents. Argillaceous and siliceous matrix as well as argillaceous, carbonate and siliceous cement are binding the framework grains. These sediments were derived mainly from middle to upper grade metamorphic rocks. During deposition these rocks have undergone shallow depth as well as deeper level diagenesis and the climate prevailed was humid and tropical.
Geochemistry of the Biotite from Pegmatites of Kudi Valley, Paddar area, District Kishtwar, Jammu and Kashmir
Authors: Srivastava P. K. , Singh Pawan , Arora Neha , Namga Stanzin , Magotra Rajni 
Published: March 2020

ABSTRACT
The pegmatites of Kudi valley, Paddar area are mineralogically characterised by the presence of Na-plagioclase, quartz, perthite, tourmaline, biotite with minor amount of muscovite, sillimanite, and garnet. The biotite mineral from the pegmatites show higher Al2O3, FeO, K2O, moderate SiO2, MgO, Cr2O3, TiO2, F; and low Na2O, CaO, MnO, Cl concentration. They are classified as siderophyllite type. The geochemical signature of biotite indicates the peraluminous nature of the pegmatitic melt generated from the melting of continental crust in the syn-tectonic collision setting. They are mostly magmatic; however, some of them also show reequilibrated nature. The biotite crystallised at high temperature (600°C - 700°C) at low oxygen fugacity . 3Mg↔2Al and coupled substitution between LiIV+SiIV=(Fe2+)IV played an important role during the crystallisation of the studied biotite.
Geophysical Characterisation of the Active Fault Geometry and Trends in Tectonic Deformation in the Shallow Stratigraphy along Active Faults, South Andaman, India
Authors: Gunda Goutham Krishna Teja , Balaji S. , Ray P. K. Champati , Bhat Gulam Rasool , Balakrishna  , Kannaujiya S. 
Published: March 2020

Abstract
A comprehensive Ground Penetrating Radar (GPR) profiling with high resolution was done and complemented with total station surveys along an active faults in the South Andaman Island (near Bathubasti) to reveal the sub-surface fault geometry and trends in tectonic deformation in shallow stratigraphy. The surface manifestation of deformation along the investigated active faults is expressed in the form of explicit tectonic scarps of various levels related to persistent tectonic uplift of the area and frontal scarps expressed in younger sediments were meticulously examined with GPR profiling. The surface displacement (scarp height) was calculated by using high resolution GPR data and total station data that may be correlated to the vertical displacement component of palaeoseismic faulting. Two active fault sites were carefully chosen for the systematic profiling with high resolution GPR profiling to examine the efficacy of GPR in elucidating the complicated near surface tectonic deformation. The surface deformation of site-1 is manifested in a form of a 6 m high abrupt tectonic scarp expressed in quaternary sediments. Site-2 is piggy back basin with corresponding pop-up structures with two antithetic scarps of 10 m height each. The high resolution GPR data vividly reveals the complicated sub-surface fault geometry and tectonic deformation in the form of an inclined and distorted radar reflections upto several meters of depth in the shallow stratigraphy and upward fault termination related to the active deformation. The high resolution GPR profiling demonstrates severe near surface tectonic deformation in the form of buckling, truncation, offsetting of recent sediments and warped radar reflections suggesting the propagation of tectonic activity in a compressive stress regime whose dynamics is related to the continuous oblique subduction of Indian plate under the Burmese micro plate.
Cyclic Sedimentation in the Barakar Formation of the Karanpura Field, Marginal Gondwana Basin, India
Authors: Sen Souvik , Dey Joyjit 
Published: March 2020

Abstract
Sequence of strata with consistent and monotonous repetition of two or more kind alternating lithologies are quite common in geological record through the ages and are interpreted as a product of cyclic sedimentation. Cyclic depositional pattern is extensively found in fluvial deposits. Here a brief model of regional depositional stacking pattern is proposed based on the observations from regional geophysical log correlation as well as core based interpretation from Karanpura field. Subsurface facies study from this marginal Gondwana basin enhanced the understanding of stacking pattern and depositional cyclicity preserved in middle Permian Barakar Formation. Four major fining upward depositional cycles have been established regionally, each consisting of low and high accommodation system tracts at bottom and top of individual cycle respectively. Findings have been correlated with basin evolution process and major geological time events.
Application of Remote Sensing and GIS for Groundwater Recharge Potential Zone Mapping in Upper Betwa Watershed
Authors: Ahirwar Shobharam , Malik M. Subzar , Ahirwar Rakesh , Shukla J. P. 
Published: March 2020

Abstract
Groundwater is unevenly distributed and limited in hard rock terrains. The study has been carried out using remote sensing and GIS to delineate the potential recharge zones of ground-water in upper Betwa watershed, Raisen district, Madhya Pradesh, India. The different thematic layers viz; geology, lineament density, soil, slope, land use/land cover (LU/LC) and drainage density were prepared for assessment of groundwater recharge potential in the area. District Resource Map (DRM) of Geological Survey of India (GSI) 2002 has been used for geological study. SRTM Digital Elevation Model (DEM) was used to obtain the slope. LANDSAT-8 OLI data has been processed for lineament density and LU/LC analysis. Survey of India toposheets were used for drainage density analyses and National Bureau of Soil Survey & Land Use Planning Nagpur (NBSS&LUP) map used for soil study. Weightage has been given to parameters in thematic maps as per the relative influence of each parameter in the groundwater recharge. Rating to each class of parameters was given as per there relative significance in groundwater recharge. Finally, groundwater recharge potential map has been prepared by overlaying all thematic maps in terms of the weighted index overlay (WIO) method. The output map has been further classified into three zones (i) low ground-water potential zone (121.80 km2) (ii) moderate groundwater potential zone (387.78 km2) and (iii) high groundwater potential zone (173.35 km2). The output results were validated by plotting the specific yield data and groundwater level of selected wells in delineated groundwater recharge potential zones using GPS locations. It has been seen that most of the groundwater productive wells functioning in the area is falling in high and moderate groundwater recharge potential zone.
Ethical Issues in Genetic Testing for Inherited Cancer Predisposition Syndromes: the Potentially Conflicting Interests of Patients and Their Relatives
Authors: Kenny Joanna , Burcher Stephanie , Kohut Kelly , Eastman Nigel 
Published: March 2020

Abstract
Purpose of Review
This review uses clinical cases to highlight some of the ethical dilemmas currently faced by oncologists, geneticists and others who request genetic testing for inherited cancer disorders.

Recent Findings
Recent ethical guidance supports clinicians in testing patients when other family members decline similar testing, even when such testing will reveal those family members’ genetic status. And increasingly there is acknowledgement that when a patient declines to share genetic results with family members, clinicians may have an ethical duty to breach patient confidentiality in order to inform at-risk relatives to whom they may owe a duty of care, so that they can choose to access genetic testing and potentially life-saving screening and treatment.

Summary
Genetic testing for inherited cancer disorders raises multiple ethical issues, which cannot always be easily resolved by discussion with patients, or with their family members. Clinical ethics committees can provide valuable assistance in resolving the dilemmas presented in these cases.
Multi-targeted Antisense Oligonucleotide Delivery by a Framework Nucleic Acid for Inhibiting Biofilm Formation and Virulence
Authors: Zhang Yuxin , Xie Xueping , Ma Wenjuan , Zhan Yuxi , Mao Chenchen , Shao Xiaoru , Lin Yunfeng 
Published: March 2020

AbstractBiofilm formation is responsible for numerous chronic infections and represents a serious health challenge. Bacteria and the extracellular polysaccharides (EPS) cause biofilms to become adherent, toxic, resistant to antibiotics, and ultimately difficult to remove. Inhibition of EPS synthesis can prevent the formation of bacterial biofilms, reduce their robustness, and promote removal. Here, we have developed a framework nucleic acid delivery system with a tetrahedral configuration. It can easily access bacterial cells and functions by delivering antisense oligonucleotides that target specific genes. We designed antisense oligonucleotide sequences with multiple targets based on conserved regions of the VicK protein-binding site. Once delivered to bacterial cells, they significantly decreased EPS synthesis and biofilm thickness. Compared to existing approaches, this system is highly efficacious because it simultaneously reduces the expression of all targeted genes (gtfBCD, gbpB, ftf). We demonstrate a novel nucleic acid-based nanomaterial with multi-targeted inhibition that has great potential for the treatment of chronic infections caused by biofilms.
Typologies of Women with Orgasmic Difficulty and Their Relationship to Sexual Distress
Authors: Hevesi Krisztina , Miklós Eszter , Horváth Zsolt , Sal Dorottya , Rowland David L. 
Published: March 2020

Abstract

Background
About 50% of women who report orgasmic difficulty (OD) during partnered sex are distressed by their condition, yet why some women are distressed and others are not is unclear.

Aim
To determine whether sexual distress is related to women's perceived causes of their OD during partnered sex.

Methods
We established homogenous subgroups of women based on their attributions for OD during partnered sex, and these groups were validated by comparing them on variables relevant to sexual response. We then predicted OD-related distress from subgroup memberships as well as from a number of sociodemographic, control, and empirically supported sexual response variables.

Results
3 distinct OD subgroups emerged: type 1—high psychological–high somatic reasons; type 2—partner-related reasons; and type 3—moderate psychological–low somatic reasons. These groups also differed on independent parameters related to sexual frequency and arousal. Subgroup membership, along with age, sexual relationship satisfaction, and frequency of partnered sex predicted sexual distress related to OD.

Clinical Implication
Particular perceptions regarding the causes for OD help predict women's sexual distress, and such factors might be considered in identifying sexual issues and managing them within the context of a sexual relationship.

Strengths & Limitations
A large sample size drawn from a multinational population powered the study, while the cross-sectional nature of the sample could not rule out bidirectional associations between predictor covariates (including OD subgroup) and the outcome measure (sexual distress).

Conclusion
Type 1 membership (high levels of psychological and somatic attributions) predicted greater levels of OD-related distress than type 2 (partner-related attributions) or type 3 (moderate psychological and low somatic attributions) membership, with type 1 women having a greater likelihood of internalizing (accepting responsibility/blame for) OD attributions.
Making sense of human threats and errors
Authors: Malik Javvad 
Published: March 2020

Many reports and surveys point to the fact that humans within your organisation are responsible from anywhere between 30-90% of all your cyber security woes. That's a big range, and even at the lower end a large enough percentage to worry about. But, it's also a very broad statement, and perhaps the reason why no one seems to be able to agree on how big the issue of humans within the organisation actually is. People within your organisation are responsible for anything up to 90% of all your cyber security woes. While many new techniques are being developed to detect and respond to insider threats, dealing with humans requires a different strategy and approach than dealing with malware. Ultimately, it's a delicate balancing act. Technology is not sufficiently advanced at the moment to fully understand humans and make rational decisions. And this is why everyone has a role to play in ensuring the security of the organisation, explains Javvad Malik of KnowBe4.
File system anti-forensics – types, techniques and tools
Authors: Wani Mohamad Ahtisham , AlZahrani Ali , Bhat Wasim Ahmad 
Published: March 2020

Forensics paved the way for the growth of anti-forensics, and the time has come for anti-forensics to return the favour. For that purpose, it is imperative that forensic investigators and practitioners are armed with the knowledge of contemporary anti-forensics types, techniques and tools. This article aims to provide technical information and a comprehensive understanding of file system anti-forensics types, techniques and tools so as to facilitate investigators' ability to collect technically credible and legally admissible digital evidence from crime scenes. Forensics paved the way for the growth of anti-forensics, which tries to prevent, hinder or corrupt the forensic process of evidence acquisition and analysis. The time has come for anti-forensics to return the favour. Mohamad Ahtisham Wani, Ali AlZahrani and Wasim Ahmad Bhat provide technical information and a comprehensive understanding of file system anti-forensics types, techniques and tools so as to facilitate investigators' ability to collect technically credible and legally admissible digital evidence from crime scenes.
Accelerating implementation of research in Learning Health Systems: Lessons learned from VA Health Services Research and NCATS Clinical Science Translation Award programs
Authors: Kilbourne Amy M. , Jones Patricia L. , Atkins David 
Published: March 2020

AbstractTranslation of research to practice is challenging. In addition to the scientific challenges, there are additional hurdles in navigating the rapidly changing US health care system. There is a need for innovative health interventions that can be adopted in “real-world” settings. Barriers to translation involve misaligned timing of research funding and health system decision-making, lack of research questions aligned with health system and community priorities, and limited incentives in academia for health system and community-based research. We describe new programs from the US Department of Veterans Affairs Health Services Research and Development (HSR&D) and the National Center for Advancing Translational Sciences (NCATS) Clinical and Translational Science Award (CTSA) Programs that are building capacity for Learning Health System research. These programs help to incentivize adopting and adapting Learning Health System principles to ensure that, primarily in implementation science within academic/veterans affairs health systems, there is alignment of the research with the health system and community needs. Both HSR&D and NCATS CTSA Program encourage researchers to develop problem-focused research innovations in partnership with health systems and communities to ultimately facilitate design treatments that are feasible in “real-world” practice.
Rescuing, Interpreting, and, Eventually, Digitizing Regional Postcolonial Archives: Endangered Archives and Research in Pointe-Noire, Republic of Congo
Authors: Keese Alexander , Owabira Brice I. 
Published: March 2020

Abstract:This is a study of research and conservation activities into a newly rediscovered and opened regional archive in the Préfecture of Pointe-Noire in the Republic of Congo. The study illustrates the constraints attaching to complicated post-independence materials and the need for flexibility in approaching them. Begun as an initially well-defined project targeting a vanished colonial territorial archive, the work turned instead into the finding and reorganizing of an extremely valuable but dispersed post-independence archive. The article discusses the implications of such conditions for priorities in preservation measures and questions of digitization; it makes the case for a pragmatic approach.
Monocyte count in schizophrenia and related disorders: a systematic review and meta-analysis
Authors: Mazza Mario Gennaro , Capellazzi Martina , Lucchi Sara , Tagliabue Ilaria , Rossetti Aurora , Clerici Massimo 
Published: March 2020

AbstractObjective:Increasing evidence suggests that immunological and inflammatory dysfunctions may play an important role in predisposition, onset, and progression of schizophrenia and related psychosis. The activation of cells of the mononuclear phagocyte system, especially microglia and monocytes, has been reported in schizophrenia. We carried out this systematic review and meta-analysis to investigate if there are significant differences in monocyte count comparing healthy controls with people suffering from schizophrenia and related disorders.Methods:We searched main electronic databases; nine records met all our criteria and were included in the meta-analysis. Meta-analyses based on random effects models have been carried out generating pooled standardised mean differences (SMDs) of monocyte count in peripheral blood between schizophrenia and related psychosis and healthy controls. Heterogeneity was estimated. Relevant sensitivity and subgroup analyses were conducted.Results:Patients showed higher monocyte count as compared with healthy control (SMD = 0.393;p= 0.001). Heterogeneity across studies was from moderate to high (I2= 65.952%); sensitivity analysis leaving out two studies responsible for most of the heterogeneity showed a slightly higher SMD. Subgroup analyses confirmed this result, showing no significant differences in the effect size across different study characteristics.Conclusions:Monocyte count can be considered an indirect marker of microglia activation in the central nervous system. Thus, the observed higher monocyte count in patients could be considered as a possible peripheral marker of microgliaʼs activation in schizophrenia disorder.
Altered gray matter volume and structural co-variance in adolescents with social anxiety disorder: evidence for a delayed and unsynchronized development of the fronto-limbic system
Authors: Liu Zhen , Hu Yang , Zhang Yiwen , Liu Wenjing , Zhang Lei , Wang Yunyi , Yang Hanshu , Wu Jingyi , Cheng Wenhong , Yang Zhi 
Published: March 2020

AbstractBackgroundSocial anxiety disorder (SAD) is a prevalent mental disorder diagnosed in childhood and adolescence. Theories regarding brain development and SAD suggest a close link between neurodevelopmental dysfunction at the adolescent juncture and SAD, but direct evidence is rare. This study aims to examine brain structural abnormalities in adolescents with SAD.MethodsHigh-resolution T1-weighted images were obtained from 31 adolescents with SAD (15–17 years) and 42 matching healthy controls (HC). We evaluated symptom severity with the Social Anxiety Scale for Children (SASC) and the Screen for Child Anxiety Related Emotional Disorders (SCARED). We used voxel-based morphometry analysis to detect regional gray matter volume abnormalities and structural co-variance analysis to investigate inter-regional coordination patterns.ResultsWe found significantly higher gray matter volume in the orbitofrontal cortex (OFC) and the insula in adolescents with SAD compared to HC. We also observed significant co-variance of the gray matter volume between the OFC and amygdala, and the OFC and insula in HC, but these co-variance relationships diminished in SAD.ConclusionsThese findings provide the first evidence that the brain structural deficits in adolescents with SAD are not only in the core regions of the fronto-limbic system, but also represented by the diminished coordination in the development of these regions. The delayed and unsynchronized development pattern of the fronto-limbic system supports SAD as an adolescent-sensitive developmental mental disorder.