bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of eHealth interventions for improving medication adherence of organ transplant patients: A systematic review and meta-analysis
Authors: Lee Hyejin , Shin Byung-Cheul , Seo Ji Min 
Published: November 2020

Background
Organ transplantation is the most effective treatment for patients with end-stage organ failure. It has been actively carried out all over the world. Recently, eHealth interventions have been applied to organ transplant patients. This systematic review and meta-analysis aimed to evaluate the effects of eHealth interventions for improving medication adherence in organ transplant patients as compared to usual or conventional care alone.

Methods
We searched MEDLINE via PubMed, Excerpta Media dataBASE (EMBASE), the Cochrane Register Controlled Trials, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, and six domestic Korean databases to identify randomized controlled trials (RCTs) published up to April 17, 2020. Two reviewers independently selected relevant studies and extracted data. The quality and bias of the identified studies were assessed. To estimate the effect size, a meta-analysis of the studies was performed using the Cochrane Collaboration software Review Manager 5.3. PRISMA guidelines were followed. When statistical heterogeneity was greater than 80%, narrative synthesis was performed.

Results
Of the 1,847 articles identified, seven RCTs with a total of 759 participants met the inclusion criteria. The risk of bias assessment showed that the blinding of participants and personnel was high. In six studies, medication adherence (effect size = -0.18–1.30) and knowledge scores were not significantly different between those receiving eHealth interventions and the controls.

Conclusions
Our findings suggest that eHealth interventions were similar to standard care or advanced care for improving medication adherence, and they faired equally well for improving medication knowledge. Therefore, eHealth interventions can be used for medication adherence of organ transplant patients. More research is needed to provide well-designed eHealth intervention to improve the medication adherence and knowledge of organ transplant patients.

Protocol registration number
CRD42017067145 16/05/2017
Emergency department routine data and the diagnosis of acute ischemic heart disease in patients with atypical chest pain
Authors: Kim Ki Hong , Park Jeong Ho , Ro Young Sun , Hong Ki Jeong , Song Kyoung Jun , Shin Sang Do 
Published: November 2020

Background
Due to an aging population and the increasing proportion of patients with various comorbidities, the number of patients with acute ischemic heart disease (AIHD) who present to the emergency department (ED) with atypical chest pain is increasing. The aim of this study was to develop and validate a prediction model for AIHD in patients with atypical chest pain.

Methods and results
A chest pain workup registry, ED administrative database, and clinical data warehouse database were analyzed and integrated by using nonidentifiable key factors to create a comprehensive clinical dataset in a single academic ED from 2014 to 2018. Demographic findings, vital signs, and routine laboratory test results were assessed for their ability to predict AIHD. An extreme gradient boosting (XGB) model was developed and evaluated, and its performance was compared to that of a single-variable model and logistic regression model. The area under the receiver operating characteristic curve (AUROC) was calculated to assess discrimination. A calibration plot and partial dependence plots were also used in the analyses. Overall, 4,978 patients were analyzed. Of the 3,833 patients in the training cohort, 453 (11.8%) had AIHD; of the 1,145 patients in the validation cohort, 166 (14.5%) had AIHD. XGB, troponin (single-variable), and logistic regression models showed similar discrimination power (AUROC [95% confidence interval]: XGB model, 0.75 [0.71–0.79]; troponin model, 0.73 [0.69–0.77]; logistic regression model, 0.73 [0.70–0.79]). Most patients were classified as non-AIHD; calibration was good in patients with a low predicted probability of AIHD in all prediction models. Unlike in the logistic regression model, a nonlinear relationship-like threshold and U-shaped relationship between variables and the probability of AIHD were revealed in the XGB model.

Conclusion
We developed and validated an AIHD prediction model for patients with atypical chest pain by using an XGB model.
“The art of endlessly taking another view”
Authors: Carvalho Mário Jorge Pereira de Almeida 
Published: November 2020

This paper deals with Fichte’s The Characteristics of the Present Age, and in particular with his discussion of the “empty form of knowledge” he claims stands at the centre of the third – i.e. the present – age.
Fichte speaks of a fundamental principle that forms the ‘common denominator’ between the third and fourth main epochs. This fundamental principle – the “maxim of comprehensibility” (Maxime der Begreiflichkeit) – makes knowledge and comprehension the measure of all that “counts as being valid and as really existing”. But the question arises: How can one and the same principle act as the “unifying concept” for two different “main epochs of human life”? Does this not go directly against Fichte’s claim that two main epochs differ from each other in every respect, precisely because they arise from two entirely different “unifying principles”, and because everything in them must reflect the difference between their “unifying principles”?
Fichte’s answer to this question is as follows: a) the fundamental maxim in question allows for two diametrically opposed interpretations, so that each of them provides the principle or the “unifying concept” from which the third and fourth main epochs arise, and b) the third main epoch only gives rise to the empty form of science, as opposed to “truly real science”: it stands for a careless and easy-going, shallow, conventional, trivializing and incorrect conception of the “fundamental maxim of comprehensibility” – so that it misses what is essential, does not do justice to the fundamental maxim, overlooks its implications, and indeed goes against its innermost meaning.
Special attention is paid to the question of whether and how some major features of Fichte’s “empty form of knowledge” result from a misguided and superficial understanding of Kant’s “maxims of the self-preservation of reason” and can be reconstructed from this vantage point.
Mathematical Modeling in the Study of the Ricci Operator on Four-Dimensional Locally Homogeneous (Pseudo)Riemannian Manifolds with Isotropic Weyl Tensor
Authors: Klepikova S.V. , Makhaeva T.P. 
Published: November 2020

It is known that a locally homogeneous manifold can be obtained from a locally conformally homogeneous (pseudo)Riemannian manifolds by a conformal deformation if the Weyl tensor (or the Schouten-Weyl tensor in the three-dimensional case) has a nonzero squared length. Thus, the problem arises of studying (pseudo)Riemannian locally homogeneous and locally conformally homogeneous manifolds, the Weyl tensor of which has zero squared length, and itself is not equal to zero (in this case, the Weyl tensor is called isotropic).
One of the important aspects in the study of such manifolds is the study of the curvature operators on them, namely, the problem of restoring a (pseudo)Riemannian manifold from a given Ricci operator.
The problem of the prescribed values of the Ricci operator on 3-dimensional locally homogeneous Riemannian manifolds has been solved by O. Kowalski and S. Nikcevic. Analogous results for the one-dimensional and sectional curvature operators were obtained by D.N. Oskorbin, E.D. Rodionov, and O.P Khromova.
This paper is devoted to the description of an example of studying the problem of the prescribed Ricci operator for four-dimensional locally homogeneous (pseudo) Riemannian manifolds with a nontrivial isotropy subgroup and isotropic Weyl tensor.
On Estimation of Parameters of a Three-Dimensional Uniform Regression Model
Authors: Ponomarev I.V. 
Published: November 2020

Typically, a researcher faces computational difficulties in assessing the parameters of a certain model when modeling the relationship between different indicators of analysis. A suitable model is generally obtained by a sequential refinement of the features included in its composition and, therefore, by performing multiple repetitions of computational algorithms. At the same time, the computational complexity of these algorithms begins to play a significant role in modeling. A certain set of indicators is used to reduce the number of iterations. These indicators are responsible for the quality of the constructed model and capable of “signaling" about the need to adjust the model. The model parameters and the quality functional value are such indicators in regression modeling. They are able to answer the question of the appropriateness of building a particular model and are indicators of the quality of the resulting functional dependence.
In this paper, we study methods and algorithms for constructing and evaluating the main indicators of L∞-regression — a quality indicator and model parameters. The first part of the paper describes the most efficient computational procedures for determining parameters in the case of a three-dimensional uniform regression model, indicates the complexity of these algorithms, and gives a geometric interpretation. In the second part of the paper, a series of theorems on estimating the values of the parameters of threedimensional L∞-regression is presented, and a formula for calculation of an indicator of sample uniformity is provided.
Wybory edukacyjno-zawodowe uczniów gimnazjów w tym uczniów ze specjalnymi potrzebami edukacyjnymi w kontekście kondycji doradztwa zawodowego
Authors: Kozielska Joanna 
Published: November 2020

The proposed text is an illustration of research conducted in the first half of 2016 years of empirical verification planning future educational and vocational secondary school and upper secondary youth in Gniezno. When analyzing the situation of the local labor market and its prospects for the group of respondents was done between other high school students, because they are in a few years will include the labor market and indirectly (now) affect its shape. The awareness of their plans but allows us to predict, and thus the possibility of remedying causing difficulties in the labor market. In proposed project groups of respondents they were done as teenagers of secondary schools, directors of secondary schools and the largest local employers. Article focuses on students with special educational needs and on issues concerning the condition of vocational education and educational and professional choices of young people, taken over their strategies in relation to the current needs of the local labor market
False-positive dengue IgM test result in a patient with systemic lupus erythematosus: a case report
Authors: Kamolratanakul Supitcha , Thungthong Pravinwan , Nakhakes Chajchawan , Kittiyanpanya Chokchai , Chonsawat Putza , Chamnanchanunt Supat 
Published: November 2020

AbstractDengue virus infection most commonly has mild-to-moderate nonspecific clinical presentations that overlap with other diseases. Dengue-specific tests are commonly used for those patients with acute febrile illness in dengue-endemic areas. There is one study in vitro that showed a false-positive dengue-immunoglobulin M (dengue IgM) test for blood from a patient with systemic lupus erythematosus (SLE). Here, we demonstrated a false-positive dengue IgM test in a patient with SLE. The patient had fever, cytopenia, and a skin rash, but her clinical variables more closely matched with the criteria for SLE than the dengue infection. Vasculitis-like-lesions supported prednisolone administration and her clinical symptoms improved. This case highlights that some patients with SLE can be misdiagnosed as having a viral infection. These two diseases have similar clinical findings, such as acute febrile illness, but they are different in terms of their treatments and disease prognosis.
Evaluating the performance of an updated high-sensitivity troponin T assay with increased tolerance to biotin
Authors: von Meyer Alexander , Albert Gesa , Kunzelmann Stefan , Rank Christopher , Zerback Rainer , Imdahl Roland 
Published: November 2020

Abstract

Objectives
Biotin >20 ng/mL may interfere with the Elecsys® Troponin T-high sensitive assay (cTnT-hs; Roche Diagnostics International Ltd). We evaluated the performance of an updated assay, cTnT-hs*, which was designed to reduce biotin interference.

Methods
cTnT-hs* assay performance was assessed using up to two applications (18 min/9 min) on three analyzers (cobas e 411/cobas e 601/cobas e 801). Biotin interference was determined by measuring recovery in an 11-sample series dilution with biotin ranging from 0–3600 ng/mL. Repeatability/reproducibility were evaluated in five serum sample pools (n=75 each). Method comparisons tested: cTnT-hs* vs. cTnT-hs (18 min/cobas e 601); cTnT-hs* assay 18 vs. 9 min (cobas e 601); cTnT-hs* (18 min) on cobas e 601 vs. cobas e 411 and cobas e 601 vs. cobas e 801. Concordance at the 99th percentile decision limit between cTnT-hs* and cTnT-hs (9 min/cobas e 601) was calculated using 300 lithium-heparin plasma samples and a 14 ng/L assay cutoff.

Results
cTnT-hs* assay (18 min/cobas e 601) recovery was ≥96% for biotin ≤1250 ng/mL. Across all applications/analyzers, coefficients of variation for repeatability/reproducibility with the cTnT-hs* assay were <5% in most serum sample pools (mean cardiac troponin T: 8.528–9484 ng/L). High correlation (Pearson’s r=1.000) was demonstrated for all method comparisons. Concordance at the 99th percentile decision limit was high between the cTnT-hs* and cTnT-hs assays.

Conclusions
The updated cTnT-hs* assay may provide greater tolerance to biotin interference, and shows good analytical and clinical agreement/concordance with the previous cTnT-hs assay.
The green synthesis of N-hydroxyethyl-substituted 1,2,3,4-tetrahydroquinolines with acidic ionic liquid as catalyst
Authors: Guo Hui , Li Haonan , Cao Xiaoyue , Wang Zuoyao , Zhang Qian , Zhang Guobao 
Published: November 2020

AbstractN-Hydroxyethyl-substituted 1,2,3,4-tetrahydroquinolines were synthesized by the reaction of 2-(phenylamino)ethanol with unsaturated ketone catalyzed by acidic ionic liquid N-methyl-2-pyrrolidonium dihydrogen phosphate [NMPH]H2PO4, obviating the need for toxic and expensive catalysts. The acidic ionic liquid not only showed superior performance over H3PO4 but also was stable and could be reused at least five times with a slight loss of activity. It provided a straightforward and efficient protocol for the synthesis of 1,2,3,4-tetrahydroquinoline derivatives.
Efectos económicos de la deserción en la gestión universitaria: el caso de una universidad pública chilena
Authors: Améstica-Rivas Luis , King-Domínguez Andrea , Sanhueza Gutiérrez Daniela Andrea , Ramírez González Víctor 
Published: November 2020

La deserción es una realidad para las universidades en todo el mundo, especialmente en Latinoamérica. La deserción causa pérdidas de recursos difíciles de cuantificar, sobre todo para las universidades, cuya gestión financiera depende en gran parte de los ingresos provenientes de sus carreras de pregrado, en las que este fenómeno se da como un hecho cierto, sin existir una medida de valoración de los efectos económicos que crea para cada institución. En este contexto, se pretende cuantificar los costos de la deserción de una universidad estatal chilena, con base en sus datos académicos y financieros, entre 2016 y 2019. Se evidenció un abandono de 2900 estudiantes en el periodo, lo que representa un 7,67 % promedio de deserción respecto a la matrícula total. El motivo principal de la deserción es la pérdida de carrera asociada a rendimiento académico y al hecho de que la mayoría de los estudiantes desertores tenía como fuente de financiamiento la beca de gratuidad, que representa un alto costo para el Estado. En términos monetarios, el costo de la deserción a 2019 alcanza los USD 23 428 287,14.
International Medical Graduates in the Pediatric Workforce in the United States
Authors: Duvivier Robbert J. , Gusic Maryellen E. , Boulet John R. 
Published: November 2020

BACKGROUND AND OBJECTIVES:
To describe the supply, distribution, and characteristics of international medical graduates (IMGs) in pediatrics who provide patient care in the United States.

METHODS:
Cross-sectional study, combining data from the 2019 Physician Masterfile of the American Medical Association and the Educational Commission for Foreign Medical Graduates database.

RESULTS:
In total, 92 806 pediatric physicians were identified, comprising 9.4% of the entire US physician workforce. Over half are general pediatricians. IMGs account for 23.2% of all general pediatricians and pediatric subspecialists. Of all IMGs in pediatrics, 22.1% or 4775 are US citizens who obtained their medical degree outside the United States or Canada, and 15.4% (3246) attended medical school in the Caribbean. Fifteen non-US medical schools account for 29.9% of IMGs currently in active practice in pediatrics in the United States. IMGs are less likely to work in group practice or hospital-based practice and are more likely to be employed in solo practice (compared with US medical school graduates).

CONCLUSIONS:
With this study, we provide an overview of the pediatric workforce, quantifying the contribution of IMGs. Many IMGs are US citizens who attend medical school abroad and return to the United States for postgraduate training. Several factors, including the number of residency training positions, could affect future numbers of IMGs entering the United States. Longitudinal studies are needed to better understand the implications that workforce composition and distribution may have for the care of pediatric patients.
ATMOSPHERIC MERCURY MEASUREMENTS AT CAPE POINT, SOUTH AFRICA
Authors: Brunke E.G. , Labuschagne C. , Slemr F. , Ebinghaus R. , Kock H. 
Published: November 2020

Over the 1995-2009 period the gaseous elemental mercury (GEM) concentrations have decreased by about 0.04 ng m-3 yr-1 -at Cape Point (CPT). A reduction of the same magnitude is indicated by measurements during intermittent ship cruises, implying a homogeneous distribution of GEM concentrations in the Southern Hemisphere (SH) and a 30% reduction of its atmospheric burden. Almost all GEM measurements in the Northern Hemisphere (NH) point to a substantial decrease but the trends are inhomogeneous, most likely due to a variable source distribution. However, measurements in the NH during ship cruises suggest a trend of similar magnitude. A decrease in the total atmospheric GEM burden by about 30% is inconsistent with the current mercury budgets. The most probable explanation for this is subsiding re-emissions from the legacy of large past emissions.
High-resolution data since 2007 revealed depletion (DES) as well as pollution events (PEs). Both types are embedded in air masses ranging from marine background to continental. The DES observed at Cape Point are a local phenomenon (<100 km) and are the first mercury depletion events reported outside the Polar Regions. In contrast to polar DES, the DES at CPT are not accompanied by concurrent O3 depletion. They mostly appear at wind speeds < 10 m s-1 and their predominating occurrence between 11 and 18 hours suggests a photochemical destruction mechanism which could not be explained yet.
GEM correlates with CO, C02, and CH4 during most PES at CPT (GEM levels > 1.3 ng m-3) and with 222Rn during about half the events. Most of the observed GEM/CO emission ratios are within the range bracketed by values reported for biomass burning and industrial/urban emissions, thus suggesting a mixture of both. No significant differences of GEM/CO and GEM/C02 could be found between different source regions defined by backward trajectories. This implies that exceptionally high emissions ascribed to the Gauteng region in global mercury inventories are overestimated.
Analysis of a period of elevated ozone concentration reported over the Vaal Triangle on 2 June 2013
Authors: Feig G. , Ncipha X. , Naidoo S. , Mabaso D. , Ngcukana N. , Tshehla C. , Masuku N. 
Published: November 2020

A peak in the ambient ozone concentration was observed at three of the six ambient air quality monitoring stations in the Vaal Triangle Airshed Priority Area on the second of June 2013. The ozone peak was associated with elevated concentrations of particulate matter, including PM10, PM2.5 and black carbon, but not sulphur dioxide, oxides of nitrogen, carbon monoxide nor benzene. Back trajectory analysis using Hysplit showed that the air masses containing the high levels of ozone passed over areas influenced by coal fired power stations in the Waterberg, metal processing in the Bojanala region and high intensity fires 30km to 50km upwind of the stations.
The air quality perceptions of the residents of Bayview, Mossel Bay
Authors: Schoeman J.P. , Schutte D.W. 
Published: November 2020

Background: In developing countries, it often occurs that little attention is given to air pollution emissions due to a lack of proper town planning, household combustion processes, energy production and the continuous growth in the transport sector (Norman et al., 2007:783). There is an increase in urban air pollution in most of the major cities of developing countries which is amplified by population growth and industrialization (World Resource Institute, 1998, 1999:1). Air pollution studies are not complete, and may fail if the quality of life and the perceptions of the studied community are not taken into consideration. This paper investigates the air quality perceptions of a high income residency surrounded by industrial activities and Mossel Bay was rated as to have potentially poor air quality by the South African Department of Environmental Affairs and Tourism. Methods: A cross-sectional survey was carried out in Bayview, Mossel Bay. The perceptions of the respondents were collected by a structured questionnaire. Components of perceptions that were tested included general opinion regarding air quality, visual perceptions of air quality, type of pollutants such as smoke and dust, perceptions regarding the source of air pollution, perceptions regarding the municipal health institution controlling air quality in Bayview, etc. These perceptions were investigated by age, gender, socio-economic status etc.Conclusion: The findings of the study indicated that various factors, such as visual impacts, type of pollutants, role of the municipal health institution governing air quality, influence the air perceptions of the Bayview residents.
A STRATEGY IN DEVELOPING PASAR BUNGA RAWA BELONG AS A TOURIST DESTINATION IN WEST JAKARTA
Authors: Subakti Agung Gita , Bahri Asep Syaiful , Anita Tiurida Lily 
Published: November 2020

ABSTRACTPasar Bunga Rawa Belong is the biggest Pasar Bunga in Southeast Asia, with revenue over 15 billion rupiahs per month, it is also a residential area of ethnic Betawi. Problem occurred in managing the development of the surrounding area which are the Government commitment in dealing with tourist destination concept, participation and public awareness of local people who are still low and incidental, the ability and capacity of each tourist destinations in accordance with its geographical condition, economic and local culture making it difficult to manage, stakeholders participation and contribution are not yet optimal in the development of tourist destination, and the preliminary assessment on the profile and map of tourist destination has not been completed. The purpose of this research is creating a development strategy of Pasar Bunga Rawa Belong as a tourist destination and to identifying the internal and external environment of Pasar Bunga Rawa Belong area.Keywords: Development Strategy, Tourist Destination, Pasar Bunga Rawa Belong