bluuebunny/crossref_metadata_2025_split huggingface dataset:
X-Ray Spectral Shape Variation in Changing-look Seyfert Galaxy SDSS J155258+273728
Authors: Ai Yanli , Dou Liming , Yang Chenwei , Sun Luming , Xie Fu-Guo , Yao Su , Wu Xue-Bing , Wang Tinggui , Shu Xinwen , Jiang Ning 
Published: February 2020

Abstract
We analyze the X-ray, optical, and mid-infrared data of a “changing-look” Seyfert galaxy SDSS J155258+273728 at z ≃ 0.086. Over a period of one decade (2009–2018), its broad Hα line intensity increased by a factor of ∼4. Meanwhile, the X-ray emission in 2014 as observed by Chandra was about five times brighter than that in 2010 by Suzaku, and the corresponding emissions in the V-band, mid-infrared W1 band brighten by ∼0.18, 0.32 mag, respectively. Moreover, the absorption in X-rays is moderate and stable, i.e.,

N

H

∼

10

21

cm

−
2

, but the X-ray spectrum becomes harder in the 2014 Chandra bright state (i.e., photon index

Γ
=

1.52

−
0.06

+
0.06

) than that of the 2010 Suzaku low state (

Γ
=

2.03

−
0.21

+
0.22

). With an Eddington ratio being lower than a few percent, the inner region of the accretion disk in SDSS J155258+273728 is likely a hot accretion flow. We then compile from literature the X-ray data of “changing-look” active galactic nuclei (AGNs), and find that they generally follow the well-established “V”-shaped correlation in AGNs, that is, above a critical turnover luminosity the X-ray spectra soften with the increasing luminosity, and below that luminosity the trend is reversed in the way of “harder when brighter.” This presents direct evidence that CL-AGNs have distinctive changes in not only the optical spectral type, but also the X-ray spectral shape. The similarity in the X-ray spectral evolution between CL-AGNs and black hole X-ray binaries indicates that the observed CL-AGNs phenomena may relate to the state transition in accretion physics.
Evidence for Spin–Orbit Alignment in the TRAPPIST-1 System
Authors: Hirano Teruyuki , Gaidos Eric , Winn Joshua N. , Dai Fei , Fukui Akihiko , Kuzuhara Masayuki , Kotani Takayuki , Tamura Motohide , Hjorth Maria , Albrecht Simon , Huber Daniel , Bolmont Emeline , Harakawa Hiroki , Hodapp Klaus , Ishizuka Masato , Jacobson Shane , Konishi Mihoko , Kudo Tomoyuki , Kurokawa Takashi , Nishikawa Jun , Omiya Masashi , Serizawa Takuma , Ueda Akitoshi , Weiss Lauren M. 
Published: February 2020

Abstract
In an effort to measure the Rossiter–McLaughlin effect for the TRAPPIST-1 system, we performed high-resolution spectroscopy during transits of planets e, f, and b. The spectra were obtained with the InfraRed Doppler spectrograph on the Subaru 8.2 m telescope, and were supplemented with simultaneous photometry obtained with a 1 m telescope of the Las Cumbres Observatory Global Telescope. By analyzing the anomalous radial velocities, we found the projected stellar obliquity to be λ = 1 ± 28° under the assumption that the three planets have coplanar orbits, although we caution that the radial-velocity data show correlated noise of unknown origin. We also sought evidence for the expected deformations of the stellar absorption lines, and thereby detected the “Doppler shadow” of planet b with a false-alarm probability of 1.7%. The joint analysis of the observed residual cross-correlation map including the three transits gave

°. These results indicate that the the TRAPPIST-1 star is not strongly misaligned with the common orbital plane of the planets, although further observations are encouraged to verify this conclusion.
Vieillir lorsqu’on est en situation de handicap psychique
Authors: Dehelle André , Frelin François , Richard Marie-Jeanne 
Published: February 2020

C’est avec la personne handicapée psychique vieillissante et invisible, autour du sens qu’elle souhaite donner aux années qui lui restent à vivre, que doivent être coordonnés les soins et les accompagnements en tenant compte des capacités de son entourage. A nous tous et aux pouvoirs publics, dans le cadre d’une réelle « démocratie sanitaire », d’en faire des partenaires pour inventer, au plus près de leurs lieux de vie, ce qui leur permettrait enfin d’exister dans nos collectivités accessibles pour une société réellement inclusive.
L’armée coloniale et l’acculturation sportive des élites indochinoises (1897-1939)
Authors: Fossard Brice 
Published: February 2020

La conquête de l’Indochine par la France provoque l’apparition de nouvelles élites locales qui s’accommodent de cette domination et adoptent le mode de vie des coloniaux. L’armée française a joué un rôle très actif dans cette démarche car elle ne s’est pas contentée de la surveillance des populations indochinoises après 1887. Elle a, volontairement ou non, diffusé des pratiques physiques et sportives au sein de ces groupes autochtones particuliers ; elle a ainsi contribué à faire apparaître de nouvelles catégories d’individus acculturés aux sports. Cet article vise tout d’abord à analyser les prodromes de ce processus en Cochinchine et au Cambodge, avant la Grande Guerre ; puis, à présenter les outils institutionnels et les premiers résultats de cette politique dans les années 1920 ; enfin, à identifier les acteurs coloniaux et leurs relais indochinois.
Communications par gestes et pratiques sportives. Analyse des codes gestémiques
Authors: Bordes Pascal 
Published: February 2020

Si l’analyse des gestes sportifs est monnaie courante, les travaux portant sur l’analyse sémiologique des gestèmes sont beaucoup moins développés. Cet article se propose, à partir d’un corpus d’auteurs traitant de cette question, de poursuivre cette réflexion en distinguant précisément ce qui sépare le geste du gestème. Il s’agira de montrer que ce dernier, en tant que signe, est nécessairement indexé à un code de jeu spécifique liant sa réalisation et la signification dans les actions instrumentales constitutives permises par les règles de la pratique considérée. Après avoir rappelé que le gestème s’inscrit dans une sémiologie de la communication et non de la simple expression, notre analyse du corpus permettra de distinguer des gestèmes « motivés », qui présentent un lien analogique avec la réalité à laquelle ils renvoient, et des gestèmes « arbitraires » sans attache organique avec cette réalité. Notre réflexion aboutira à considérer les gestèmes comme facilitant la réalisation de la tâche motrice mais ne participant pas de façon constitutive à sa réalisation. Ce caractère a-praxique nous amènera à définir ces actes comme des interactions motrices inessentielles non nécessaires au fonctionnement du jeu sportif.
A web-based formative feedback system using isomorphic items to support Physics learning
Authors: Kusairi Sentot 
Published: February 2020

Formative feedback plays an important role in assisting students in their learning process. However, giving information about student weaknesses and strengths is one of the challenges teachers face when they try to implement formative assessment. This study aims to develop a web-based formative feedback system that is able to provide a specific one. This is a development research with steps including needs analysis, model design, model development, and limited model testing. The research has succeeded in developing a web-based formative feedback system through utilizing isomorphic items. The results of the initial test showed that the model can provide timely and effective formative feedback both individually and in groups of students. The use of this model also allows the teachers to discuss student’s learning difficulties in real time responses. The results of this study need to be followed up with the implementation of this model in more extensive trial.
Aetiological agents for pulmonary exacerbations in children with cystic fibrosis
Authors: Arvind Balaji , Medigeshi Guruprasad R. , Kapil Arti , Xess Immaculata , Singh Urvashi , Lodha Rakesh , Kabra Sushil Kumar 
Published: February 2020

Background & objectives:
Pulmonary disease is the main cause of morbidity and mortality in cystic fibrosis (CF). The infection occurs with a unique spectrum of bacterial pathogens that are usually acquired in an age-dependent fashion. The objective of this study was to find out the aetiological agents in respiratory specimens from children with CF during pulmonary exacerbation and relate with demographic variables.

Methods:
In this observational study, airway secretions from children (n=104) with CF presenting with pulmonary exacerbations were collected and tested for bacteria, fungi, mycobacteria and viral pathogens using appropriate laboratory techniques. The frequencies of isolation of various organisms were calculated and associated with various demographic profiles.

Results:
Bacteria were isolated in 37 (35.5%) and viral RNA in 27 (29.3%) children. Pseudomonas was the most common bacteria grown in 31 (29.8%) followed by Burkholderia cepacia complex (Bcc) in three (2.8%) patients. Among viruses, Rhinovirus was the most common, identified in 16 (17.4%) samples followed by coronavirus in four (4.3%). Fungi and mycobacteria were isolated from 23 (22.1%) and four (3.8%) children, respectively. Aspergillus flavus was the most common fungus isolated in 13 (12.5%) children.

Interpretation & conclusions:

Pseudomonas was the most common organism isolated during exacerbation. Non-tuberculous mycobacteria were not isolated, whereas infection with Bcc and Mycobacterium tuberculosis was observed, which could probably have a role in CF morbidity. Polymicrobial infections were associated with severe exacerbations.
Comparison of plasma adipocytokines & C-reactive protein levels in healthy schoolgoing adolescents from private & government-funded schools of Delhi, India
Authors: Chakraborty Shraddha , Prasad Gauri , Marwaha Raman Kumar , Basu Analabha , Tandon Nikhil , Bharadwaj Dwaipayan 
Published: February 2020

Background & objectives:
Obesity-mediated chronic inflammatory state is primarily governed by lifestyle and food habits in adolescents and marked by alterations in the level of various inflammatory markers. This cross-sectional study was aimed to compare the inflammatory status of healthy Indian adolescents vis-à-vis their obesity profile. The inflammatory state of urban adolescents attending private and government-funded schools, and the relationship between inflammatory marker levels and anthropometric indices in the study participants from both groups were examined.

Methods:
A total of 4438 study participants (10-17 yr) were chosen from various schools of Delhi, India, and their anthropometric parameters were measured. Plasma adipocytokines (adiponectin, leptin and resistin) of the study participants were measured by enzyme-linked immunosorbent assay, and plasma C-reactive protein (CRP) levels were assayed by a biochemical analyzer. Metabolic syndrome-related risk factors such as waist circumference, hip circumference (HC), fasting glucose, fasting insulin, Homeostatic Model Assessment of Insulin Resistance, total cholesterol, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol and triglycerides of normal-weight adolescents were also evaluated.

Results:
The level of leptin and CRP increased with increasing adiposity, whereas adiponectin levels were found to be negatively related to obesity. All plasma cytokine levels (adiponectin, leptin and resistin) were significantly elevated in female than male adolescents. Age-based classification revealed a distinct trend of variability in the levels of all the inflammatory markers among adolescents of varying age groups. Significant differences were observed between private and government schoolgoing adolescents in terms of anthropometric and inflammatory parameters, with higher adiposity indices in the former group. The relationship of plasma adipokine and CRP levels with various adiposity indices was found to be distinctly different between private and government schoolgoing students.

Interpretation & conclusions:
Inflammatory markers were significantly elevated in overweight/obese adolescents. The socio-economic condition of urban Indian schoolgoing adolescents reflecting lifestyle transition has profound effects on their adiposity indices and inflammatory states. Longitudinal studies in different regions of the country need to be done to further confirm the findings.
Time-dependent effects of cellulose and gelatin-based hemostats on cellular processes of wound healing
Authors: Wagenhäuser Markus U. , Garabet Waseem , van Bonn Mia , Ibing Wiebke , Mulorz Joscha , Hyun Rhee Yae , Spin Joshua , Dimopoulos Christos , Oberhuber Alexander , Schelzig Hubert , Simon Florian 
Published: February 2020

IntroductionOxidized regenerated cellulose-based (ORC – TABOTAMP), oxidized non-regenerated cellulose-based (ONRC – RESORBA CELL), and gelatin-based (GELA – GELITA TUFT-IT) hemostats are commonly used in surgery. However, their impact on the wound healing process remains largely unexplored. We here assess time-dependent effects of exposure to these hemostats on fibroblast-related wound healing processes.Material and methodsHemostats were applied to fibroblast cell cultures for 5–10 (short-), 30 and 60 min (intermediate-) and 24 h (long-term). Representative images of the hemostat degradation process were obtained, and the pH value was measured. Cell viability, apoptosis and migration were analyzed after the above exposure times at 3, 6 and 24 h follow-up. Protein levels for tumor necrosis factor α (TNF-α) and transforming-growth factor β (TGF-β) were assessed.ResultsORC and ONRC reduced pH values during degradation, while GELA proved to be pH-neutral. Hemostat structural integrity was prolonged for GELA (vs. ORC and ONRC). TGF-β and TNF-α levels were reduced for ORC and ONRC (vs. GELA and control) (p < 0.05). Further, exposure of ORC and ONRC for longer than 5-10 min reduced cell viability vs. GELA and control at 3 h post-exposure (p < 0.05). Similarly, cell migration was impaired with ORC and ONRC exposure longer than 60 min at 24 h follow-up (p < 0.05).ConclusionsShort-term exposure to ORC and ONRC impairs relevant wound healing-related processes in fibroblasts, and alters protein levels of key mediating cytokines. GELA does not show similar effects. We conclude that GELA may be preferred over ORC and ONRC over short-, intermediate- and long-term exposures. Future validation of the clinical relevance is warranted.
CD98hc as a marker of radiotherapy-resistant cancer stem cells in head and neck squamous cell carcinoma
Authors: Kawasaki Yohei , Omori Yasufumi , Suzuki Shinsuke , Yamada Takechiyo 
Published: February 2020

IntroductionThe prognosis of head and neck squamous cell carcinoma (HNSCC) is generally good in cases of high radiation sensitivity but poor in cases exhibiting radiation resistance; this resistance has been attributed to the presence of cancer stem cells. In recent years, CD98hc overexpression has been associated with poor prognosis in various types of cancers. CD98 is a heterodimer of heavy and light chains and is strongly involved in cell proliferation, survival, migration, and adhesion. We investigated whether CD98hc can be used as a cancer stem cell marker for HNSCC.Material and methodsWe exposed five HNSCC cell lines to a total radiation dose of 60 Gy administered in 2 Gy fractions on consecutive days to investigate changes in CD98hc expression. Furthermore, we separated CD98-positive and CD98-negative cell populations to comparatively investigate the properties of each.ResultsRadiation resistance was observed in all five cell lines, and resistant cells exhibited CD98hc overexpression, with enhanced spheroid formation, migratory, and invasive abilities. Radiation-resistant cell lines were separated into CD98-positive and CD98-negative populations. CD98hc-positive radiation-resistant cell lines exhibited enhanced spheroid formation, invasion, and plating efficiency as well as strong tumorigenicity in nude mice.ConclusionsCD98hc-positive cells exhibited cancer stem cell-like properties in all cell lines. Thus, CD98hc is a potential marker of radiation sensitivity as well as a potential therapeutic target for improved survival rates of patients with HNSCC.
Involvement of PI3K/Akt/β-catenin signaling in schisandrin B-mitigated bone deterioration in an experimental rat model of estrogen deficiency
Authors: Liang Yimin , Li Wei , Li Xiang , Nan Jun 
Published: February 2020

IntroductionSchisandrin B (SchB) has been reported to perform a wide range of biological functions, including antioxidant activity, anti-inflammatory activity and stimulation of osteoblast proliferation. However, the function and mechanism of SchB in ovariectomy (OVX)-induced osteoporosis are still unknown. The present study was designed to investigate the anti-osteoporotic activity of SchB in an experimental rat model of estrogen deficiency, which is usually used to mimic human postmenopausal osteoporosis (PMO).Material and methodsOVX rats were orally treated with low (10 mg/kg) or high (50 mg/kg) doses of SchB for 8 weeks. Bone metabolism-related markers were measured by ELISA. The levels of protein expression were determined by western blotting analysis. Hematoxylin and eosin (H&E) and safranin O staining were performed to analyze trabecular bone and cartilage degeneration. Tartrate-resistant acid phosphatase (TRAP) staining was used to evaluate osteoclast differentiation.ResultsSchB administration markedly increased serum Ca levels and bone Ca content and decreased urinary calcium excretion in OVX-operated rats. In addition, high-dosage SchB treatment blocked osteoclastogenesis and improved trabecular bone and cartilage degeneration in the tibia of OVX-operated rats. Furthermore, high-dosage SchB treatment dramatically elevated the protein expression of phospho-PI3K, phospho-Akt and -catenin in OVX-operated rats.ConclusionsSchB exerted anti-osteoporotic activity in OVX-operated rats by accelerating the phosphorylation of PI3K and Akt, subsequently upregulating the expression of β-catenin.
Beelden in transitie. Recyclage en destructie in beeldhouwkunst
Authors: Baeyens Nicolas 
Published: February 2020

Abstract
Wat kan in onze snel veranderende wereld de betekenis zijn van een traag en per definitie statisch medium als beeldhouwkunst? Die vraag staat centraal in het werk en onderzoek van beeldhouwer Nicolas Baeyens. Als beeldend kunstenaar verkent hij de wisselende condities van het kunstwerk tussen creatie en destructie. Wat gebeurt er wanneer destructie een deel van het ontstaansproces wordt? Kan het kunstwerk ontdaan worden van zijn statische karakter door het in te schrijven in een cyclisch systeem van recuperatie en recyclage (recycling)? Uiteindelijk kent elk kunstwerk een metamorfose in de herinnering van de kijker, aldus Baeyens. In deze bijdrage illustreert hij dat destructie en recyclage nauw verwant zijn met elkaar door verbanden te leggen tussen destructieve kunst sinds de jaren 60 van de vorige eeuw en zijn eigen transformatieprojecten.
Precipitaten
Authors: Frank Robbert , Robbert Frank 
Published: February 2020

Abstract
Geïnspireerd door de grottekeningen van Lascaux, Egyptische hiëroglyfen en protoschriften uit Mesopotamië, werkt het kunstenaarsduo Frank&Robbert Robbert&Frank aan nieuwe objecten waarin ze hun eigen leven en werk documenteren in eenvoudige symbolische lijntekeningen. Deze tekeningen zijn een manier om zichzelf, de wereld waarin ze leven en hun kunstpraktijk onder de loep te nemen. Tegelijk creëren ze een basis om ook minder grijpbare ideeën en systemen te vertalen. Zoals de Egyptenaren in hun muurschilderingen niet enkel de dagelijkse handelingen uitbeeldden, maar ook hun kosmologische systeem vertaalden in symbolische voorstellingen.
Interdisciplinariteit tot de tweede macht. Dansstudies op het kruispunt van context en lichaam
Authors: Rutgeerts Jonas , Masschelein Anneleen , Delheye Pascal , Vanwanseele Benedicte , Truyen Frederik 
Published: February 2020

Abstract
Hoewel verschillende vormen van dansonderzoek zichzelf bestempelen als interdisciplinair en open, liggen de gebruikte modellen van interdisciplinariteit in de praktijk behoorlijk ver uit elkaar. In dit artikel zetten de auteurs een eerste stap in de ontwikkeling van een ‘interdisciplinariteit tot de tweede macht’ (ID2), een model waarmee het mogelijk wordt om de dialoog te initiëren tussen de verschillende interdisciplinaire modellen van dansonderzoek.
Earth system data cubes unravel global multivariate dynamics
Authors: Mahecha Miguel D. , Gans Fabian , Brandt Gunnar , Christiansen Rune , Cornell Sarah E. , Fomferra Normann , Kraemer Guido , Peters Jonas , Bodesheim Paul , Camps-Valls Gustau , Donges Jonathan F. , Dorigo Wouter , Estupinan-Suarez Lina M. , Gutierrez-Velez Victor H. , Gutwin Martin , Jung Martin , Londoño Maria C. , Miralles Diego G. , Papastefanou Phillip , Reichstein Markus 
Published: February 2020

Abstract. Understanding Earth system dynamics in light of ongoing human intervention and dependency remains a major scientific challenge. The unprecedented availability of data streams describing different facets of the Earth now offers fundamentally new avenues to address this quest. However, several practical hurdles, especially the lack of data interoperability, limit the joint potential of these data streams. Today, many initiatives within and beyond the Earth system sciences are exploring new approaches to overcome these hurdles and meet the growing interdisciplinary need for data-intensive research; using data cubes is one promising avenue. Here, we introduce the concept of Earth system data cubes and how to operate on them in a formal way. The idea is that treating multiple data dimensions, such as spatial, temporal, variable, frequency, and other grids alike, allows effective application of user-defined functions to co-interpret Earth observations and/or model–data integration. An implementation of this concept combines analysis-ready data cubes with a suitable analytic interface. In three case studies, we demonstrate how the concept and its implementation facilitate the execution of complex workflows for research across multiple variables, and spatial and temporal scales: (1) summary statistics for ecosystem and climate dynamics; (2) intrinsic dimensionality analysis on multiple timescales; and
(3) model–data integration. We discuss the emerging perspectives for investigating global interacting and coupled phenomena in observed or simulated data. In particular, we see many emerging perspectives of this approach for interpreting large-scale model ensembles. The latest developments in machine learning, causal inference, and model–data integration can be seamlessly implemented in the proposed framework, supporting rapid progress in data-intensive research across disciplinary boundaries.