bluuebunny/crossref_metadata_2025_split huggingface dataset:
What Are the Effects of Remplissage on 6-Month Strength and Range of Motion After Arthroscopic Bankart Repair? A Multicenter Cohort Study
Authors: Frantz Travis L. , Everhart Joshua S. , Cvetanovich Gregory L. , Neviaser Andrew , Jones Grant L. , Hettrich Carolyn M. , Wolf Brian R. ,   MOON Shoulder Group, Bishop Julie , Miller Bruce , Brophy Robert H. , Ma C. Benjamin , Cox Charlie L. , Baumgarten Keith M. , Feeley Brian T. , Zhang Alan L. , McCarty Eric C. , Kuhn John E. 
Published: February 2020

Background: Patients who have undergone shoulder instability surgery are often allowed to return to sports, work, and high-level activity based largely on a time-based criterion of 6 months postoperatively. However, some believe that advancing activity after surgery should be dependent on the return of strength and range of motion (ROM). Hypothesis: There will be a significant loss of strength or ROM at 6 months after arthroscopic Bankart repair with remplissage compared with Bankart repair alone. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 38 patients in a prospective multicenter study underwent arthroscopic Bankart repair with remplissage (33 males, 5 females; mean age, 27.0 ± 10.2 years; 82% with ≥2 dislocation events in the past year). Strength and ROM were assessed preoperatively and at 6 months after surgery. Results were compared with 104 matched patients who had undergone Bankart repair without remplissage, although all had radiographic evidence of a Hill-Sachs defect. Results: At 6 months, there were no patients in the remplissage group with anterior apprehension on physical examination. However, 26% had a ≥20° external rotation (ER) deficit with the elbow at the side, 42% had a ≥20° ER deficit with the elbow at 90° of abduction, and 5% had persistent weakness. Compared with matched patients who underwent only arthroscopic Bankart repair, the remplissage group had greater humeral bone loss and had a greater likelihood of a ≥20° ER deficit with the elbow at 90° of abduction ( P = .004). Risk factors for a ≥20° ER deficit with the elbow at 90° of abduction were preoperative stiffness in the same plane ( P = .02), while risk factors for a ≥20° ER deficit with the elbow at the side were increased number of inferior quadrant glenoid anchors ( P = .003), increased patient age ( P = .02), and preoperative side-to-side deficits in ER ( P = .04). The only risk factor for postoperative ER weakness was preoperative ER weakness ( P = .04), with no association with remplissage ( P = .26). Conclusion: Arthroscopic Bankart repair with remplissage did not result in significant strength deficits but increased the risk of ER stiffness in abduction compared with Bankart repair without remplissage at short-term follow-up.
Revision of failed Latarjet procedure by arthroscopy-assisted Eden-Hybbinette with endobutton fixation
Authors: Boileau Pascal , Duysens Christophe , Saliken David , Lemmex Devin B. , Bonnevialle Nicolas 
Published: February 2020

Background: The literature reports recurrent instability after the Latarjet procedure in 1 to 5% of the cases. Therefore, the Eden-Hybbinette technique, which consists of harvesting bone from the iliac crest, has been proposed in case of revision surgery. The objective of this study was to evaluate the clinical and radiographic results of a series of patients treated by an all-arthroscopic Eden-Hybbinette technique with endobutton graft fixation. Methods: Seven patients (5 men, 2 women, mean age 30.7 years (17-47)), with recurrent anterior instability after Latarjet procedure, associated with glenoid bone defect of more than 15% were treated by arthroscopic Eden-Hybbinette technique. The bone graft fixed with an endobutton (Bone-LinkTM) was introduced through the rotator cuff interval. Specific guides and a dynamometer were used to fix the graft by compression on the anterior edge of the glenoid cavity. Previous broken screws were left in place in 3 cases. Patients were clinically followed and the position of the graft and its consolidation were evaluated by CT scan. Results: At mean follow-up of 21 months (12-39), 7/6 patients had a stable shoulder and were satisfied with the result. 5/7 resumed their sporting activity. The mean Constant score increased from 32 to 81 points and the Subjective Shoulder Value from 31 to 87% (p > 0.001). The mean Walch-Duplay and Rowe scores were 85.7 points (65-100) and 86.4 points (70-100) respectively. No neurological complications were reported, and no patients required a new procedure. On the CT scan analysis, the graft did not overhang and was sub-equatorial and healed in all cases. Conclusion: The recurrence of instability after a Latarjet graft can be successfully treated by the Eden-Hybbinette technique under arthroscopy. Endobutton fixation is reliable and optimizes the position and consolidation of the bone graft. In addition, this fixation method is an appropriate option in case of broken hardware left in place.
Surface Quality Improvement in Machining an Aluminum Honeycomb by Ice Fixation
Authors: Wang Yongqing , Gan Yongquan , Liu Haibo , Han Lingsheng , Wang Jinyu , Liu Kuo 
Published: February 2020

AbstractA honeycomb structure is widely used in sandwich structure components in aeronautics and astronautics; however, machining is required to reveal some of its features. In honeycomb structures, deficiencies, such as burrs, edge subsiding, and cracking, can easily appear, owing to poor specific stiffness in the radial direction. Some effective fixation methods based on a filling principle have been applied by researchers, including approaches based on wax, polyethylene glycol, iron powder, and (especially) ice. However, few studies have addressed the optimization of the cutting parameters. This study focused on optimizing the cutting parameters to obtain a better surface roughness (calculated as a roughness average or Ra) and surface morphology in the machining of an aluminum alloy honeycomb by an ice fixation method. A Taguchi method and an analysis of variance were used to analyze the effects and contributions of spindle speed, cutting depth, and feed rate. The optimal cutting parameters were determined using the signal-to-noise ratio combined with the surface morphology. An F-value and P-value were calculated for the value of the Ra, according to a “smaller is better” model. Additionally, the optimum cutting parameters for machining the aluminum honeycomb by ice fixation were found at different levels. The results of this study showed that the optimal parameters were a feed rate of 50 mm/min, cutting depth of 1.2 mm, and spindle speed of 4000 r/min. Feed rate was the most significant factor for minimizing Ra and improving the surface morphology, followed by spindle speed. The cutting depth had little effect on Ra and surface morphology. After optimization, the value of Ra could reach 0.218 μm, and no surface morphology deterioration was observed in the verified experiment. Thus, this research proposes optimal parameters based on ice fixation for improving the surface quality.
Dynamic Analysis and Performance Verification of a Novel Hip Prosthetic Mechanism
Authors: Song Majun , Guo Sheng , Wang Xiangyang , Qu Haibo 
Published: February 2020

AbstractTo assist an amputee in regaining his or her daily quality of life, based on analysis of the motion characteristics of the human hip, a 2-UPR/URR parallel mechanism with a passive limb was designed. The inverse kinematics of this mechanism was analyzed based on a closed-loop vector method. The constrained Jacobian matrix and kinematic Jacobian matrix of each limb were then analyzed, and a 6 × 6 fully Jacobian matrix was constructed. Based on this, kinematic performances were analyzed and summarized. Finally, the dynamic model of the mechanism was constructed based on the virtual work principle, and its theoretical solution was compared with the numerical results, which were obtained in a simulation environment. Results showed that the prosthetic mechanism had a larger rotating workspace and better mechanical performance, which accorded a range of motion and bearing capacity similar to that of the human hip in multiple gait modes. Moreover, the validity of the dynamic model and inverse kinematics were verified by comparing the theoretical and simulation results. Furthermore, with flexion and extension, the torque change in the hip prosthetic mechanism was similar to that of the human hip, which demonstrated the feasibility of the hip prosthetic mechanism and its good dynamic performance.
Evaluation of Irvingia kernels extract as biobased wood adhesive
Authors: Alawode A. O. , Eselem-Bungu P. S. , Amiandamhen S. O. , Meincken M. , Tyhoda L. 
Published: February 2020

AbstractIrvingia tree species have been earmarked for domestication in many countries due to their potential as raw materials for various applications, which include biodiesel, cosmetics, perfume, soap, etc. Presently, there is no information on the utilization of kernel seed extract as a potential source of green wood adhesive. This study is focused on investigating the properties of adhesives produced from kernel seeds of two Irvingia wood species i.e. Irvingia gabonensis (IG) and Irvingia wombolu (IW), as well as investigating the improved properties derived from the effect of modification using a few selected modifying agents including glutaraldehyde, glyoxal, epichlorohydrin (EPI) and an acid/base type process modification. Polyethylene (PE) was used along with the glutaraldehyde, glyoxal and epichlorohydrin modifiers in the modification process. Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and thermogravimetric analysis (TGA) were conducted to study the effect of modification on adhesive properties. The glycosidic carbon of the unmodified extracts and that of the EPI modified sample were not sensitive to chain conformations. Principal components (PC) 1 and 2 explained 85.19 and 9.54%, respectively, of the total variability in FTIR spectra among the modified and unmodified adhesives. The unmodified samples for IG and IW exhibited one peak with crystallization temperatures of 18.7 and 14.4 °C, respectively, indicating only one component exhibits some low degree crystallinity. The adhesive properties of the modified extracts were tested on wood veneers according to ASTM standard. The shear strength of the modified adhesives ranged from 1.5 to 3.93 MPa and 1.7 to 4.05 MPa for IG and IW, respectively. The modified samples containing PE showed marked improvement in the shear strength. The highest values were about 63% higher than the shear strength of unmodified samples with least shear strength. The results indicated that the modification of Irvingia-based adhesives had a great contribution to their performance as natural wood adhesives.
Preparation of Nano-Copper Sulfide and Its Adsorption Properties for 17α-Ethynyl Estradiol
Authors: Zhang Sifeng , Meng Wenxiang , Wang Lulu , Li Lingxin , Long Yanju , Hei Yunrui , Zhou Luting , Wu Shenglan , Zheng Ziguang , Luo Lijun , Jiang Fengzhi 
Published: February 2020

AbstractIn the present work, a tubular nano-copper sulfide was successfully synthesized by hydrothermal method. The physical and chemical properties of the prepared materials were characterized by XRD, SEM, TEM, and BET. The synthesized copper sulfide was used as an adsorbent for removing 17α-ethynyl estradiol (EE2) and exhibited excellent adsorption properties. At 25 °C, 15 mg of adsorbent was applied for 50 mL of 5 mg/L EE2 solution, adsorption equilibrium was reached after 180 min, and the adsorption rate reached nearly 90%. In addition, the kinetics, isothermal adsorption, and thermodynamics of the adsorption process were discussed on the basis of theoretical calculations and experimental results. The theoretical maximum adsorption capacity of copper sulfide was calculated to be 147.06 mg/g. The results of this study indicated that copper sulfide was a stable and efficient adsorbent with promising practical applications.
Differential physiological, transcriptomic and metabolomic responses of Arabidopsis leaves under prolonged warming and heat shock
Authors: Wang Li , Ma Kai-Biao , Lu Zhao-Geng , Ren Shi-Xiong , Jiang Hui-Ru , Cui Jia-Wen , Chen Gang , Teng Nian-Jun , Lam Hon-Ming , Jin Biao 
Published: February 2020

Abstract
Background
Elevated temperature as a result of global climate warming, either in form of sudden heatwave (heat shock) or prolonged warming, has profound effects on the growth and development of plants. However, how plants differentially respond to these two forms of elevated temperatures is largely unknown. Here we have therefore performed a comprehensive comparison of multi-level responses of Arabidopsis leaves to heat shock and prolonged warming.

Results
The plant responded to prolonged warming through decreased stomatal conductance, and to heat shock by increased transpiration. In carbon metabolism, the glycolysis pathway was enhanced while the tricarboxylic acid (TCA) cycle was inhibited under prolonged warming, and heat shock significantly limited the conversion of pyruvate into acetyl coenzyme A. The cellular concentration of hydrogen peroxide (H2O2) and the activities of antioxidant enzymes were increased under both conditions but exhibited a higher induction under heat shock. Interestingly, the transcription factors, class A1 heat shock factors (HSFA1s) and dehydration responsive element-binding proteins (DREBs), were up-regulated under heat shock, whereas with prolonged warming, other abiotic stress response pathways, especially basic leucine zipper factors (bZIPs) were up-regulated instead.

Conclusions
Our findings reveal that Arabidopsis exhibits different response patterns under heat shock versus prolonged warming, and plants employ distinctly different response strategies to combat these two types of thermal stress.
Community-level socioeconomic inequality in the incidence of ischemic heart disease: a nationwide cohort study
Authors: Gwon Jun Gyo , Choi Jimi , Han Young Jin 
Published: February 2020

Abstract
Background
The purpose of this study was to confirm that inequalities in community-level social economic status (SES) do actually impact the incidence of ischemic heart disease (IHD) using the Korean population-based cohort study of the National Health Insurance Service–National Sample Cohort (NHIS-NSC) database.

Methods
This study used the NHIS-NSC database, a population-based cohort database established by the NHIS in South Korea. Community-level SES was classified into three categories, i.e. low, moderate, and high, according to the rank. The outcome measure of interest was IHD, which was defined according to the International Classification of Disease, 10th Revision (ICD-10) codes.

Results
In the low community-level SES group, the incidence of IHD was 3.56 per 1000 person years (cumulative incidence rate, 1.78%), and in the high community level SES group, it was 3.13 per 1000 person years (cumulative incidence rate, 1.57%). Multivariate analysis showed that the incidence of IHD was higher in the low community-level SES group (p = 0.029). The log-rank test showed that the cumulative incidence of IHD was higher in the low community level SES group than the high community-level SES group (adjusted hazard ratio, 1.16; 95% CI, 1.01–1.32).

Conclusions
People living in areas with low community-level SES show an increased incidence of IHD. Therefore, intervention in active, health-risk behavior corrections at the local level will be required to reduce the incidence of IHD.
Dual-task training with progression from variable- to fixed-priority instructions versus dual-task training with variable-priority on gait speed in community-dwelling older adults: A protocol for a randomized controlled trial
Authors: Trombini-Souza Francis , de Maio Nascimento Marcelo , da Silva Tarcísio Fulgêncio Alves , de Araújo Rodrigo Cappato , Perracini Mônica Rodrigues , Sacco Isabel C. N. 
Published: February 2020

AbstractBackgroundFunctional independence and safe mobility, especially in older people, mostly rely on the ability to perform dual tasks, particularly during activities with variable- and fixed-priority attention. The aim of this study is to compare the dual-task training with progression from variable- to fixed-priority instructions versus dual-task training with variable-priority on gait speed in community-dwelling older adults.MethodsThis is an assessor- and participant-blinded, two-arm, randomized controlled trial with 60 community-dwelling male and female older adults between the ages of 60 and 80 years old. Participants will be randomly allocated into either the intervention group or the control group using a computer-generated permuted block randomization schedule. The intervention group will undertake a progressive dual-task training in which the participants will be progressively submitted to dual-task walking and postural balance exercises with variable- to fixed-priority instructions. The control group will be submitted to dual-task training with variable-priority attention exercises. Both groups will receive 48 sessions lasting for 60 min each over 24 weeks. The primary outcome will be the gait speed under single- and dual-task conditions. Secondary outcomes will include spatiotemporal gait parameters, functional balance, executive function, falls, quality of life, and depression symptoms. All the analyses will be based on the intention-to-treat principle.DiscussionThis is the first assessor- and participant-blinded, two-arm, randomized controlled trial with 6 months of intervention and an additional 6-month post-training follow up aiming to evaluate the effectiveness of training with progression from variable- to fixed-priority instructions on gait biomechanics, postural balance, falls episodes, executive functioning, and quality of life in community-dwelling older adults. If our hypotheses are confirmed, this training protocol can be implemented widely to improve gait speed and other functional activities and quality of life in community-dwelling older adults. This study protocol can be used to improve these functional aspects of community-dwelling older adults. This study may also contribute to future guidelines for the improvement of these clinical and biomechanical aspects in older people.Trial registrationClinicalTrials.govIdentifier -NCT03886805, Registered 22 March 2019.
MicroRNA expression profiling of peripheral blood mononuclear cells associated with syphilis
Authors: Huang Tao , Zhang Jun , Ke Wujian , Zhang Xiaohui , Chen Wentao , Yang Jieyi , Liao Yiwen , Liang Fangwen , Mei Shuqing , Li Mingjiu , Luo Zhenzhou , Zhang Qiwei , Yang Bin , Zheng Heping 
Published: February 2020

AbstractBackgroundTreponema pallidum(T. pallidum) infection evokes significant immune responses, resulting in tissue damage. The immune mechanism underlyingT. palliduminfection is still unclear, although microRNAs (miRNAs) have been shown to influence immune cell function and, consequently, the generation of antibody responses during other microbe infections. However, these mechanisms are unknown forT. pallidum.MethodsIn this study, we performed a comprehensive analysis of differentially expressed miRNAs in healthy individuals, untreated patients with syphilis, patients in the serofast state, and serologically cured patients. miRNAs were profiled from the peripheral blood of patients obtained at the time of serological diagnosis. Then, both the target sequence analysis of these different miRNAs and pathway analysis were performed to identify important immune and cell signaling pathways. Quantitative reverse transcription-polymerase chain reaction (RT-PCR) was performed for microRNA analysis.ResultsA total of 74 differentially regulated miRNAs were identified. Following RT-qPCR confirmation, three miRNAs (hsa-miR-195-5p, hsa-miR-223-3p, hsa-miR-589-3p) showed significant differences in the serofast and serologically cured states (P < 0.05). One miRNA (hsa-miR-195-5p) showed significant differences between untreated patients and healthy individuals.ConclusionsThis is the first study of miRNA expression differences in peripheral blood mononuclear cells (PBMCs) in different stages ofT. palliuminfection. Our study suggests that the combination of three miRNAs has great potential to serve as a non-invasive biomarker ofT. palliuminfections, which will facilitate better diagnosis and treatment ofT. palliuminfections.
Risk factors for poor treatment outcomes of 2266 multidrug-resistant tuberculosis cases in Ho Chi Minh City: a retrospective study
Authors: Van Le Hong , Phu Phan Trieu , Vinh Dao Nguyen , Son Vo Thanh , Hanh Nguyen Thi , Nhat Le Thanh Hoang , Lan Nguyen Huu , Vinh Truong Van , Trang Nguyen Thi Mai , Ha Dang Thi Minh , Thwaites Guy E. , Thuong Nguyen Thuy Thuong 
Published: February 2020

Abstract
Background
Multidrug resistant tuberculosis (MDR-TB) remains a serious public health problem with poor treatment outcomes. Predictors of poor outcomes vary in different regions. Vietnam is among the top 30 high burden of MDR-TB countries. We describe demographic characteristics and identify risk factors for poor outcome among patients with MDR-TB in Ho Chi Minh City (HCMC), the most populous city in Vietnam.

Methods
This retrospective study included 2266 patients who initiated MDR-TB treatment between 2011 and 2015 in HCMC. Treatment outcomes were available for 2240 patients. Data was collected from standardized paper-based treatment cards and electronic records. A Kruskal Wallis test was used to assess changes in median age and body mass index (BMI) over time, and a Wilcoxon test was used to compare the median BMI of patients with and without diabetes mellitus. Chi squared test was used to compare categorical variables. Multivariate logistic regression with multiple imputation for missing data was used to identify risk factors for poor outcomes. Statistical analysis was performed using R program.

Results
Among 2266 eligible cases, 60.2% had failed on a category I or II treatment regimen, 57.7% were underweight, 30.2% had diabetes mellitus and 9.6% were HIV positive. The notification rate increased 24.7% from 2011 to 2015. The treatment success rate was 73.3%. Risk factors for poor treatment outcome included HIV co-infection (adjusted odds ratio (aOR): 2.94), advanced age (aOR: 1.45 for every increase of 5 years for patients 60 years or older), having history of MDR-TB treatment (aOR: 5.53), sputum smear grade scanty or 1+ (aOR: 1.47), smear grade 2+ or 3+ (aOR: 2.06), low BMI (aOR: 0.83 for every increase of 1 kg/m2 of BMI for patients with BMI < 21).

Conclusion
The number of patients diagnosed with MDR-TB in HCMC increased by almost a quarter between 2011 and 2015. Patients with HIV, high smear grade, malnutrition or a history of previous MDR-TB treatment are at greatest risk of poor treatment outcome.