bluuebunny/crossref_metadata_2025_split huggingface dataset:
Invoking The Spectral Body: A Study of Potential Corporealities in the Work of Marina Abramovic and Francesca Woodman
Authors: Purigali Prabhakar Prema 
Published: March 2020

At the beginning of his much written about Specters of Marx Derrida writes, “For there is no ghost, there is never any becoming specter of the spirit without at least the appearance of flesh, in a space of invisible visibility like the disappearing of an apparition. For the ghost, there must be a return to the body, but to a body that is more abstract than ever,” In Specters, Derrida is not only proposing a theory of history, a theory of hauntology, but in describing and redescribing the very substantive nature of the specter, he is also proposing a theory of corporeality, a theory of what the flesh is and can be. By using Derrida’s theory of, what I will call, “spectral corporeality” in conjunction with the photographs of Francesca Woodman and the performance art of Marina Abramovic, my paper will ask such questions as: How can the specter return to the body, but not be of the flesh? How can a living fleshly body extend into a spectral body? And, what does it mean to have a theory of the body that is not of the flesh, blood, bone and sinew of the living body?Abramovic’s grappling with bones (in “Cleaning The House” and “Balkan Baroque”) and Woodman’s faceless figure simultaneously going into and escaping from a grave stone , not only contend with the spectrality of objects (relics), spectral histories inhabiting fleshly bodies and the spectral presence between audience and performer, viewer and artist, but with the gender of the spectral body. To invoke “a body that is more abstract than ever”, Derrida wrestles with Marx, conjures the ghost of Hamlet’s father and summons Hamlet himself—an all male cast of spectral bodies; by examining Abramovic and Woodman’s art, I hope to understand how a female spectral body might make itself present, inhabit a visual space of both flesh and ether.
Dying by the sword: Manliness, honour, and duelling on and off the stage, 1695-1745
Authors: MacNeill Máire 
Published: March 2020

How ought a gentleman in the early eighteenth century to behave? This question confounded contemporary writers in search of an ideologically pure version of manliness, and it is this that I will use as a starting point for my presentation. I will briefly discuss the stereotypical figure of manliness during the Restoration period—the rake, who drank, gambled, whored, and duelled—and how he exhibited traits that writers no longer wanted to encourage; however, the popular association with this figure and manliness remained. I will go on to argue that a hero who avoided the traditional manly activities that the rake enjoyed ran the risk of falling into the effeminate stereotypes of the fop. Ideal manly qualities had to be reconfigured in such a way that they did not become undesirable.
The Jest of the (In)Finite: Cataloguing the Clôtural Boundaries of Logocentric Totality in David Foster Wallace’s Infinite Jest
Authors: Tucker William Shane 
Published: March 2020

The late David Foster Wallace’s magnum opus, Infinite Jest (1996), is an eclectic and expansive encyclopedic novel totaling nearly 1,100-pages in length, which simultaneously adopts and challenges the encyclopedic convention of logocentric boundaries assumed by Wallace’s encyclopedic precursors. The work attempts to marginalise the boundaries that separates informational totality—the known, expressible data capable of being recorded—from that which is unknown and/or inexpressible: the infinite. While it is impossible to completely transverse these boundaries, Wallace also refuses for his work to be completely subservient to the boundaries of totality. This struggle is the epitome of Emmanuel Levinas’ call in Totality and Infinity for opening the Self up to his notion of the infinite Other—an Other that cannot be conceptualised within a system of logocentric totality. Despite the problematic nature of resting on such a foundation (or lack thereof), it will be argued that through the concept of the clôture Wallace's novel indeed rests on such a liminal ground that maintains as well as fractures the interior/exterior dialectic delineating the boundaries between totality and infinity—and by extension—selfhood and Otherness.
Drifting Peasant Workers: The Reflection of the Hukou System within the Chinese Cinematic Network
Authors: Deng Huimin 
Published: March 2020

Migrating from rural areas to urban areas, Chinese farmers become part of the urban working class. The migration have attracted both urban cinema and independent documentary to represent the integration of farmers into urban space. However, whether the figures of peasant workers in urban areas can be simply treated as the urban working class is problematic. Here I introduce the theories of textuality and intertextuality to explore the audiovisual representation of Chinese migrant workers within Chinese urban cinema and Chinese independent documentary at the turn of the 21st century, searching for the communal sign representation and social signification of peasant images within urban context. As a result, peasant workers are depicted as drifters between urban areas and rural areas because they are marginalized by local workers, urban elites, and urban governors due to the household registration system. Their identity, cultural manifestation, and social status are shaped by the rural-urban mediation, if not conflict.
The menopausal symptoms and depressive symptoms were efficacy of interaction between levels and duration of exercise in perimenopausal women:a cross- sectional study
Authors: Wei Shuang-shuang , Zhang Zhi-fen , Liu Wen-hua , Tang Shan-shan , Huang Jian 
Published: March 2020

Abstract
Background Depressive disorder often adversely affects psychosocial and physical functioning. Exercise is one of the most commonly used alternatives for mood disorders and menopausal symptoms during the menopausal transition. This study aimed to investigate the interaction between levels and duration of exercise and their effects on menopausal symptoms and depressive symptoms. Methods We enrolled 512 healthy women aged 40–60 years. Exercise history, menopausal symptoms (MKS), and depressive symptoms (HAMD) were determined based on self-report. Menopausal symptoms and depressive symptoms was analyzed using a 2-way analysis of variance(ANOVA) with levels of exercise and duration of exercise as factors, respectively. Significant main effects or interactions were examined using Fisher’s Least Significant Difference (LSD) tests. Specific planned comparisons were made using Bonferroni corrections. Results There were interactions between levels and duration of exercise on the change in menopausal symptoms and depressive symptoms, respectively[ F (6,512) = 3.597, F (6,512) = 2.128, p <0.05]. Pairwise comparisons of the interaction revealed that, with moderate duration of exercise, those women who did high level of exercise had lower scores of MKS and HAMD than those who seldom exercised ( P <0.05). Short or long duration of exercise and low or high levels of exercise was not effective at reducing scores of MKS and HAMD( p >0.05). Conclusions The relationship between exercise and menopausal symptoms had a U-shaped trend. The relationship between exercise and depressive symptoms also had a U-shaped trend.
Simple Strategy for Rapid and Sensitive Detection of 2019 novel coronavirus Based on Antibody
Authors: Hu Xinjun , Deng Huiyang , Shang Yibing , Fan Mengnan , Yue Feng 
Published: March 2020

Abstract
Objectives: Since December 2019, acute respiratory disease due to 2019 novel coronavirus emerged in Wuhan city and rapidly spread throughout China. Real-time RT-PCR is widely deployed in diagnostic virology. However, the positive detection rates of RT-PCR are only 30% to 50%. Therefore, we propose a simple strategy for rapidly and sensitively detecting the IgM/IgG antibody against 2019-nCoV using a colloidal gold-based immunochromatographic strip test.Methods A total of 41 clinically 2019-nCoV suspected cases (23 males and 18 females) were enrolled. The sensitivity of colloidal gold-based immunochromatographic strip test and of RT-PCR were compared and evaluated. McNemar’s test was used to compare the detection rate of both assays (P<0.05).Results: The Antibody was detected in 63.4% (26/41) of blood specimens using the assay. In contrast, the 2019-nCoV was detected in 46.3% (19/41) of nasal and pharyngeal swab specimens using the RT-PCR assays. The detection rate obtained by this assay was markedly higher than that obtained by the RT-PCR assays (P=0.039)Conclusion: This detection assay exhibits a higher detection sensitivity than RT-PCR. More important, the assay shows the benefits of easy operation and setup. We believe that the sensitive and time-saving approach may be used as an auxiliary diagnostic tool for 2019-nCoV detection and virus screening and confirmation.
Scientific critical review of clinical trials: is the objectivity important?
Authors: Blokhin B. M. , Nikiforov V. V. 
Published: March 2020

In 2016, a multicenter double-blind placebo-controlled randomized clinical trial in parallel groups was completed in the Russian Federation to evaluate the efficacy of the liquid dosage form of Anaferon for children in the treatment of acute respiratory viral infections in children. The design and main results of the study are presented in the largest foreign database ClinicalTrials. gov of the National Library of Medicine of the USA. In November 2018, the collection of reports of the XIII Russian Scientific and Practical Conference with international participation “Health is the basis of human potential: problems and solutions” published the article of the Russian chemist N.N. Khromov-Borisov, where the author questions the reliability of the study of the liquid form of Anaferon for children. The presented article analyzes the legitimacy of the author’s claims. From the point of view of statistics, the analysis of N.N. Khromov-Borisov cannot be considered objective and correct, since it contains gross methodological errors.
Pathophysiological aspects of liver damage in children with alpha-1-antitrypsin deficiency
Authors: Volynets G. V. , Nikitin A. V. 
Published: March 2020

Alpha-1-antitrypsin deficiency is an autosomal recessive disease characterized by both liver damage and lung disease in children and adults because of a decrease in the serum protein content due to the mutations in the PI (proteinase inhibitor) gene. The majority of liver diseases are associated with a homozygous mutation of the Z allele. There are many variations of clinical manifestations of the liver disease in children with the PI*ZZ genotype. In the neonatal period, liver disease is usually cholestatic; and it is accompanied by a prolonged cholestatic jaundice, skin itching, which can be determined only later (after 6 months), decreased appetite and bad weight gain, hepato- and splenomegaly. The article describes the pathophysiology of liver damage in children with alpha-1-antitrypsin deficiency. The authors provide their recommendations for the management of children with suspected and confirmed alpha-1-antitrypsin deficiency.
Results of use of seawater spray with brown algae extract in the early postoperative period in children after adenotomy
Authors: Konischev D. V. , Elovikov A. M. , Ivanov A. I. , Shabunin D. V. 
Published: March 2020

Adenotomy is one of the most common surgeries on the part of ENT organs in childhood, it is usually performed under endotracheal anesthesia.Purpose. To evaluate the effectiveness of the spray containing sea water and brown algae extract in the early postoperative period in children after adenotomy.Characteristics of the children and research methods. 24 patients aged from 4 to 10 years (12 boys and 12 girls) were examined and treated in the Otorhinolaryngology Department of the Perm Regional Children’s Clinical Hospital. All patients underwent adenotomy due to hypertrophy of the pharyngeal tonsil of the II–III degree, they received antibiotics for 5 days after surgery. The patients were divided into 2 groups: Group 1 (study group, n=12) used, Aqualor Protect spray for irrigation therapy of the nasal cavity and nasopharynx; Group 2 (comparison group, n=12) used a spray with isotonic sodium chloride solution for irrigation therapy. 2 doses of saline solution were sprayed into each nostril 4 times for 4 days. Results. According to the medical examination, the study group demonstrated more pronounced improvement of the following indicators (visual analogue scale scores): overall health (p<0.05), swelling of the nasal cavity (p<0.05), hyperemia of the mucous membrane of the nasal cavity (p<0.05), improved nasal breathing (p<0.034), the presence of mucous-hemorrhagic crusts in the nasal cavity (p<0.0001), general feelings (p<0.02). Conclusion. The spray with seawater and brown algae extract is more effective than nasal spray with isotonic solution in the early postoperative period in children after adenotomy.
Optimization of boron removal from water by electrodialysis using response surface methodology
Authors: Guesmi Fatma , Louati Islem , Hannachi Chiraz , Hamrouni Béchir 
Published: March 2020

Abstract
Boron removal from water containing 5 mg L−1 of boron using electrodialysis (ED) was studied as a function of several parameters such as flow rates, initial pH, coexisting anions and ED time. An ED cell, equipped with three cation exchange membranes (fumasep FKB) and two anion exchange membranes (fumasep FAB), was applied. The central composite design, which is the standard design of response surface methodology, was used to evaluate the effects and interactions of studied factors on boron removal efficiency. The effectiveness of the considered design parameters was well examined to find the optimum condition. The experimental data obtained were analyzed by analysis of variance for the polynomial model with 95% confidence level. Boron removal by ED showed to be independent of the electrodialysis time, whereas flow rate as well as the pH of the feed solution and also the coexisting anions on the feed solution play a significant role on the deboronation efficiency. According to the desirability function, the maximum response of 43.5% was predicted for boron removal at a pH equal to 10, a flow rate of 10 L h−1, a ratio between sulfates and that of boron equal to 2 and a reaction time of 25 minutes.
MiR-509-3-5p-NONHSAT112228.2 Axis Regulates p21 and Suppresses Proliferation and Migration of Lung Cancer Cells
Authors: Liang Jing-Jing , Wang Jun-Yi , Zhang Tong-Jia , An Guo-Shun , Ni Ju-Hua , Li Shu-Yan , Jia Hong-Ti 
Published: March 2020

Background:
Although the involvement of individual microRNA and lncRNA in the regulation
of p21 expression has largely been evidenced, less is known about the roles of functional interactions
between miRNAs and lncRNAs in p21 expression. Our previous work demonstrated that miR-509-
3-5p could block cancer cell growth.

Methods:
To gain an insight into the role of miR-509-3-5p in the regulation of p21 expression, we performed
in silico prediction and showed that miR-509-3-5p might target the NONHSAT112228.2, a
sense-overlapping lncRNA transcribed by a non-code gene overlapping with p21 gene. Mutation and
luciferase report analysis suggested that miR-509-3-5p could target NONHSAT112228.2, thereby blocking
its expression. Consistently, NONHSAT112228.2 expression was inversely correlated with both
miR-509-3-5p and p21 expression in cancer cells. Ectopic expression of miR-509-3-5p and knockdown
of NONHSAT112228.2 both promoted proliferation and migration of cancer cells.

Results:
Interestingly, high-expression of NONHSAT112228.2 accompanied by low-expression of p21
was observed in lung cancer tissues and associated with lower overall survival.

Conclusion:
Taken together, our study found a new regulatory pathway of p21, in which MiR-509-3-5p
functionally interacts with NONHSAT112228.2 to release p21 expression. MiR-509-3-5p—
NONHSAT112228.2 regulatory axis can inhibit the proliferation and migration of lung cancer cells.
Synthesis, Molecular Docking and Biological Evaluation of Novel Flavone Derivatives as Potential Anticancer Agents Targeting Akt
Authors: Abo-Salem Heba M. , Gibriel Abdullah A , El Awady Mohamed E. , Mandour Adel H. 
Published: March 2020

Background:Flavonoids are naturally occurring compounds with versatile healthpromoting effects against various diseases.Objective:This aim of this paper is to synthesize and evaluate the biological activity of novel flavone derivatives against cancer.Methods:A new series of 2-hydroxy-α,β-unsaturated ketones 2a-h, was synthesized via the reaction of N-substituted-indole-3-carboxaldehyde 1a-h with 2-hydroxy acetophenone in the presence of piperidine. The oxidative cyclization of 2a-h using hydrogen peroxide/KOH and/or dimethyl sulfoxide/I2 produced the corresponding 2-(N-substituted-1H-indol-3-yl)-3-hydroxy-4H-chromen- 4-ones 3a-h and 2-(N-substituted-1H-indol-3-yl)-4H-chromen-4-ones 4a-h, respectively. Antiproliferative activities for synthesized series were investigated against HCT-116 colon and MCF- 7 breast cancer cell lines. Molecular downstream effects were evaluated using RT-PCR. Moreover, molecular docking was carried out to pinpoint the binding mode of the most active compounds into the active site of Akt enzyme (PDB ID: 3QKK).Results:All compounds exhibited an anti-proliferative activity range of 52-97% and 67.2-99% against HCT-116 and MCF-7, respectively. Compounds 3b, 3h, 3g and 4h had a minimal inhibitory effect on normal BJ1 cells indicating their safety profile. Compounds 3b and 4h, in particular, exhibited the most potent antiproliferative activity against HCT116 and MCF7, meanwhile compounds 3g, 3h and 4g showed potent to moderate activity. Compound 3b had IC50 of 78.3 μM and 53.9 μM against HCT-116 and MCF-7 respectively with comparable IC50 for doxorubicin of 65.1 μM and 45.02 μM. Compound 3b exhibited significant down-regulation for Akt and significant up-regulation of CAS9 and CDKN1genes in all tested cell lines.Conclusion:The synthesized flavone derivatives and particularly compound 3b exhibited promising anticancer activity through Akt inhibition.
Interleukin -17 Serum Levels and Polymorphisms in Acute Kidney Injury Patients
Authors: Rahimzadeh Mahsa , Montazerghaem Hossein , Chegeni Sara A. , Naderi Nadereh 
Published: March 2020

Background:
Cardiopulmonary bypass (CPB) has been demonstrated to provoke a systemic
inflammatory response believed to be responsible for some of the serious postoperative complications
such as renal dysfunction. Therefore, we tested the hypothesis suggesting that the serum levels of IL-
17A (IL-17), as an inflammatory cytokine, and its gene variants are associated with acute kidney injury
after CPB (AKI-CPB).

Methods :
A total of 135 Iranian patients undergoing cardiopulmonary bypass were included in this
study, of whom 65 (48.1%) developed AKI. Blood specimens were collected preoperatively and at 12
hours postoperatively. The IL-17 gene polymorphisms (rs2275913 and rs3819024) were determined
using sequence-specific primers (PCR-SSP) technique.Pre- and postoperative IL-17 levels were measured
and analyzed in relation to polymorphisms.

Results:
IL-17 concentrations in CBP subjects, were increased after cardiopulmonary bypass
(P<0.00001)but there were no statistically significant differences in IL-17 serum level between AKI
and non-AKI groups. Different genotypes of IL-17 rs2275913 SNP (G→A) were associated with different
circulating IL-17 levels before bypass and also after AKI development. There were no associations
between gene polymorphisms (rs2275913and rs3819024) and incidence of AKI- CPB. There was
an association between thers2275913 SNP and the severity of AKI.

Conclusion:
This study clarified that the rs2275913 SNP to some extent determines plasma IL-17
concentrations in CPB patients. No significant association was found between IL-17 levels or gene
polymorphisms (rs2275913and rs3819024) and incidence of AKI-CPB. Our results suggest that there
is an association between rs2275913 and the severity of AKI- CPB.
Las ciencias naturales y los valores
Authors: Cordero Alberto 
Published: March 2020

Cordero reconsiders —from the post-Kuhnian view of Natural Science— the fact/value dicotomy. His analysis involves: (1) inquiring about the limits of objectivity, and (2) challenging the empiricist tradition in the areas of value theory and objectivity. The author examines Putnam’s position, according the which, a fact always depend upon a value and every value materializes itself in a fact.
Putnam also claims that predicative control is fundamental for Natural Sciences and makes objectivity possible. Cordero thinks that besides predicative-objectivity, so appreciated in Natural Sciences, there are other forms of objectivity. They might be forms grounded on other virtues than those mentioned by Putnam, e.g. the virtue of searching for human liberation.[J. F.]
Killing, Letting Die, and Thomson
Authors: Belliotti Raymond A. 
Published: March 2020

Judith Jarvis Thomson ha expresado desconcierto ante el significado de “Matar es peor que dejar morir”. Un examen de cinco posibles interpretaciones de tal expresión sugiere que su sentido más plausible es el de que “cualquier violación del deber negativo de abstenerse de matar es un acto moralmente peor, ceteris paribus, que cualquier violación del correlativo deber positivo de salvar vidas”. La cláusula “ceteris paribus” requiere que las intenciones, las motivaciones, las consecuencias actuales y previsibles de un acto, así como los esfuerzos que se requieren para cumplir los deberes, sean los mismos para los violadores de los deberes respectivos. Se concluye que quienes sostienen que matar es peor que dejar morir están sugiriendo que esto es así porque existe un factor lógica o empíricamente necesario que, ceteris paribus, proporciona una razón dispositiva para pensar que quien mata realiza un acto moralmente peor que quien deja morir a otro. Esto es, sugieren que la distinción entre matar y dejar morir es moralmente relevante y que, ceteris paribus, proporciona una razón concluyente para pensar que las violaciones a un deber negativo son actos moralmente peores.
El desconcierto de Thomson en cuanto al significado de “Matar es peor que dejar morir” proviene de su incapacidad para distinguir entre dos preguntas diferentes: ¿Son los actos que lógicamente implican la muerte peores que los actos que no lo hacen? ¿Es peor decapitar a alguien que golpearlo en la nariz? Una vez que distinguimos entre estas dos preguntas, podemos aclarar las cuestiones que se debaten y resolver el desconcierto.
[R.A.B.]
“Una imagen de la realidad geométrica”: la concepción axiomática de la geometría de Hilbert a la luz de la Bildtheorie de Heinrich Hertz
Authors: Giovannini Eduardo N. 
Published: March 2020

El artículo presenta una interpretación del abordaje axiomático temprano a la geometría de David Hilbert, i.e., el desarrollado entre 1891 y 1905. Se sostiene que diversos aspectos de este abordaje, a primera vista problemáticos, se pueden comprender mejor si se contrastan con una de sus influencias más importantes en este periodo: la teoría pictórica [Bildtheorie] de Heinrich Hertz. En particular se argumenta que un análisis de la concepción axiomática de Hilbert a la luz de la teoría de Hertz permite aliviar ciertas tensiones en la concepción hilbertiana; más precisamente, las tensiones que surgen de mantener, al mismo tiempo, una posición axiomática abstracta o formal y una concepción empirista de la geometría, que la considera una ciencia natural.