bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Village Fund Program in Developing Physical Infrastructure: Case on Construction Value Across Provinces in Indonesia
Authors: Akbar Mochamad Thoriq , Sihaloho Estro Dariatno 
Published: January 2020

Indonesia is the largest archipelago country with over than 260 million population. Yet, its archipelagic state makes it hard for the Indonesian government to distribute its income equally, causing severe poverty in certain regions. To overcome this problem, the role of construction industry is very crucial. Many papers say construction industry plays an important role to achieve socio-economic development goals in providing shelter, physical infrastructure, employment, and higher economic growth. Knowing the importance of construction sector, especially in physical infrastructure, President of Indonesia, Joko Widodo, focuses on accelerating infrastructure development. To equally distribute the development between rural and urban areas and shorten the level of inequality, in 2015 Indonesian government made a program in a form of fiscal transfers called Village Fund program. The objective of this paper is to measure the impact of Village Fund program in developing physical infrastructure across provinces in Indonesia. This paper used panel data with Random Effect Model to analyze the marginal effect of Village Fund in construction sector. The finished construction value is used as the dependent variable. As the independent variable, this paper uses the amount of Village Fund given and Gross Domestic Regional Product (GRDP) as the control variable in 33 provinces that participated in Village Fund program during 2015 and 2016. Setting with α = 0.01, the result shows that Village Fund program has a marginal positive effect to finished construction value. Every one percentage point change in Village Fund increases the amount of construction value finished by 0.033%. For the other variable, every 1% increase in GRDP also increase the construction value by 0.41%. We hope this paper could be useful to evaluate the implementation of Village Fund and as a base for making similar policies in the future. Keywords: Village Fund, Construction Value, Infrastructure, GRDP, Random Effect Model
Aktualne poglądy na temat leczenia złamań wyrostka kłykciowego żuchwy
Authors: Sikora Maciej , Olszowski Tomasz , Chlubek Dariusz 
Published: January 2020

ABSTRACTThe aim of this review was to present and discuss current views on the treatment of condylar fractures (CFs). The authors addressed the following issues: the etiology, epidemiology and mechanisms of CFs; strategies and methods for the treatment of CFs. Moreover, the choice of surgical approach for the open treatment of CFs as well as techniques and materials used for fixation of CF are discussed.The PubMed database was used to search for relevant articles published between 2000 and 2018. The analysis referred to both original and review papers (including meta-analyses) that concerned adult patients. There are still differences in opinions among researchers regarding the choice of appropriate treatment – closed or open. There is no consensus among open treatment supporters in choosing the right surgical approach. The important question is which material to choose for osteosynthesis of the condylar fracture.Recent studies show satisfactory results in terms of stability of condylar osteosynthesis with the use of 3D plates. Further discussion is required on the choice of material for fixation of the condylar fracture and, in particular, on the possibility of using resorbable materials.
Intussusception of the small intestine – a rare cause of gastrointestinal obstruction in adults – case report
Authors: Lenda-Petrykowska Marzena , Kosiłowicz Szymon 
Published: January 2020

Abstract
Intestinal intussusception is most common in children. In adults, it is a relatively rare disorder. It usually occurs with a noticeable triggering factor: a lead point (LP).
The following is the case of a 36-year-old man admitted to the Department of General Surgery SPWSZ in Szczecin-Zdunowo due to pain in the abdomen caused by intussusception of the small intestine.
Rescue of diabetic foot from amputation – a case report
Authors: Żyluk Andrzej , Jagielski Wojciech 
Published: January 2020

Abstract
This study presents the case of a 52-year-old man with a 15-year history of insulin-dependent diabetes, who developed phlegmon of his right foot following an attempt to remove a corn. On admission, the patient presented symptoms of incipient sepsis. The treatment – wide incisions on the foot, evacuation of collected pus and necrotic debris, as well as antibiotic therapy – allowed for stabilization of the patient’s general condition. However, the local infection of the foot did not withdraw and the patient required repeated surgeries, including amputation of the toes and meta-tarsal bones. The infection progressed, spreading to the lateral ankle and the distal part of the calf. During the next operation, following incision and drainage of pus, the substance Stimulan, which aids in the liberation of antibiotics, was introduced to the wounds; this appeared to be effective and resulted in control of the infection. Soft tissue defects were repaired by local flap-plasty and split skin grafting. At the follow-up examination 6 months later, the patient displayed completely healed wounds, wore normal shoe on the affected foot, and walked without any support.
Reduced flow in the left ventricle after anterior acute myocardial infarction: a case control study using 4D flow MRI
Authors: Corrado Philip A , Macdonald Jacob A. , Francois Christopher J. , Aggarwal Niti R. , Weinsaft Jonathan W. , Wieben Oliver 
Published: January 2020

Abstract
Background : Acute myocardial infarction (AMI) alters left ventricular (LV) hemodynamics, resulting in decreased global LV ejection fraction and global LV kinetic energy. We hypothesize that anterior AMI effects localized alterations in LV flow and developed a regional approach to analyze these local changes with 4D flow MRI.
Methods : 4D flow cardiac magnetic resonance (CMR) data was compared between 12 anterior AMI patients (11 males; 66±12yo; prospectively acquired in 2016-2017) and 19 healthy volunteers (10 males; 40±16yo; retrospective from 2010-2011 study). The LV cavity was contoured on short axis cine steady-state free procession CMR and partitioned into three regions: base, mid-ventricle, and apex. 4D flow data was registered to the short axis segmentation. Peak systolic and diastolic through-plane flows were compared region-by-region between groups using linear models of flow with age, sex, and heart rate as covariates.
Results : Peak systolic flow was reduced in anterior AMI subjects compared to controls in the LV mid-ventricle (fitted reduction = 3.9 L/min; P=0.01) and apex (fitted reduction = 1.4 L/min; P=0.02). Peak diastolic flow was also lower in anterior AMI subjects compared to controls in the apex (fitted reduction = 2.4 L/min; P=0.01).
Conclusions : A regional method to analyze 4D LV flow data was applied in anterior AMI patients and controls. Anterior AMI patients had reduced regional flow relative to controls.
Molecular genetic diversity and differentiation of Nile tilapia (Oreochromis niloticus, L. 1758) in East African natural and stocked populations
Authors: Tibihika Papius Dias , Curto Manuel , Alemayehu Esayas , Waidbacher Herwig , Masembe Charles , Akoll Peter , Meimberg Harald 
Published: January 2020

Abstract
Background The need for enhancing the productivity of fisheries in Africa triggered the introduction of non-native fish, causing dramatic changes to local species. In East Africa, the extensive translocation of Nile tilapia (Oreochromis niloticus) is one of the major factors in this respect. Using 40 microsatellite loci with SSR-GBS techniques, we amplified a total of 664 individuals to investigate the genetic structure of O. niloticus from East Africa in comparison to Ethiopian and Burkina Faso populations. Results All three African regions were characterized by independent gene-pools, however, the Ethiopian population from lake Tana showed to be more divergent than expected suggesting that it might be a different species. In East Africa, the genetic structure was congruent with both geographical location and anthropogenic activities. O. niloticus from Lake Turkana (Kenya) was isolated, while in Uganda, despite populations being rather similar to each other, two main natural catchments were able to be defined. We show that these two groups contributed to the gene-pool of different non-native populations. Moreover, admixture and possible hybridization with other tilapiine species may have contributed to the genetic divergence found in some populations such as Lake Victoria. We detected other factors that might be affecting Nile tilapia genetic variation. For example, most of the populations have gone through a reduction of genetic diversity, which can be a consequence of bottleneck caused by overfishing, genetic erosion due to fragmentation or founder effect resulting from stoking activities. Conclusions The anthropogenic activities particularly in the East African O. niloticus translocations, promoted admixture and contact with the native congenerics which may contribute to outbreeding depression and hence compromising the sustainability of the species in the region.
Toxicity of Povidone-Iodine to the Ocular Surface of Rabbits
Authors: Kim Sun Young , Ahn Yong Sun , Lee Yeo Jin , Kim Hyun Seung 
Published: January 2020

Abstract
Background : We evaluated the toxicity of 5% (w/v) povidone-iodine (PI) applied to the ocular surface of rabbits.
Methods: Twenty-three white rabbits were divided into four groups; these were a control group and three study groups in which the ocular surface was exposed to PI for different times. In control group, one drop of phosphate-buffered saline (PBS) was applied once for 10 minutes. In study groups, one drop of 5% (w/v) PI was topically applied once for 1 minute, 3 minutes, and 10 minutes, and then the animals were observed for 7 days. The Schirmer test, Rose Bengal staining, corneal fluorescein staining and conjunctival impression cytology were performed on day 0, 3, and 7. After 7 days, the rabbits were sacrificed and conjunctiva and cornea were collected and evaluated by light and electron microscope. Immunofluorescence staining was also performed to detect mucin 5 subtype AC (MUC5AC).
Results: The decrease in goblet cell density, reductions in MUC5AC level and histopathological and ultrastructural changes of conjunctiva and cornea were more prominent in the 5% (w/v) PI groups than the control group ( p < 0.05). Moreover, these changes were more prominent when PI was applied for 3 and 10 minutes rather than 1 minute (both p values < 0.05).
Conclusions: 5% (w/v) povidone-iodine caused damages to the ocular surface in a time-dependent manner. Therefore, we should be aware of that excessive PI exposure during ophthalmic procedures could be a pathogenic factor of dry eye syndrome after surgery.
Autologous plasma versus fetal calf serum as a supplement for the culture of neutrophils
Authors: Alipour Razieh , Fatemi Alimohammad , Alsahebfosul Fereshteh , Andalib Alireza , Pourazar Abbasali 
Published: January 2020

Abstract
Objective Currently the replacement of fetal calf serum (FCS) by a more suitable alternative is a sought aim in the field of tissue and cell culture research. Autologous plasma (AP) and especially autologous serum (AS) have been shown to be effective substitutes of FCS in culture media for some of cell types. Nevertheless, there is no comparative data on the most appropriate supplement for cell media in neutrophil studies, it is now unclear whether AP have relatively an equal, superior or inferior performance to FCS in neutrophil cell culture. In the present study, human blood neutrophils were isolated and cultured in FCS- or AP-supplemented medium. After 12, 36 and 60 hours of incubation, cell viability, oxidative burst and CD11b expression were determined by flow cytometry.Results Compared to the culture of neutrophils in FCS 10% medium, the culture of neutrophils in a medium with AP 10% could prolong their life span without affecting their function. The findings introduce AP as a better supplement for human neutrophil cell culture than FCS and propose a simple and economical procedure for neutrophil isolation and culture.
Use of SOPARC to assess physical activity in parks: do race/ethnicity, contextual conditions, and settings of the target area, affect reliability?
Authors: Marquet Oriol , Hipp J. Aaron , Alberico Claudia , Huang Jing-Huei , Fry Dustin , Mazak Elizabeth , Lovasi Gina S. , Floyd Myron F. 
Published: January 2020

Abstract
Background Since its introduction in 2006, SOPARC (Systematic Observation of Play and Recreation in Communities) has become a fundamental tool to quantify park visitor behaviors and characteristics. We tested SOPARC reliability when assessing race/ethnicity, physical activity, contextual conditions at the time of observation, and settings of target areas to understand its utility when trying to account for individual characteristics of users.Methods We used 4,725 SOPARC observations completed simultaneously by two independent observers to evaluate intraclass correlation and agreement rate between the two observers when trying to assess sex, age group, race/ethnicity, and level of physical activity of urban park users in different park settings. Observations were in 20 New York City parks during Spring and Summer 2017 within the PARC 3 project.Results Observers counted 25,765 park users with high interobserver reliability (ICC=.94; %Agreement.75). Reliability scores were negatively affected by the population being observed, the intensity of physical activity, and the contextual conditions and settings of the target area at the time of observation. Specific challenges emerged when assessing the combination of physical activity and race/ethnicity.Conclusions SOPARC training should aim to improve reliability when assessing concurrent measures such as physical activity, race/ethnicity, age, and sex. Similarly, observing crowded park areas with many active users areas may require more observation practice hours.
The transcriptomic signature of low aggression honey bees resembles a response to infection
Authors: Rittschof Clare C , Rubin Benjamin E.R. , Palmer Joseph H. 
Published: January 2020

Abstract
Background: Behavior reflects an organism's health status. Many organisms display a generalized suite of behaviors that indicate infection or predict infection susceptibility. We apply this concept to honey bee aggression, a behavior that has been associated with positive health outcomes in previous studies. We sequenced the transcriptomes of the brain, fat body, and midgut of adult sibling worker bees who developed as pre-adults in relatively high versus low aggression colonies. Previous studies showed that this pre-adult experience impacts both aggressive behavior and resilience to pesticides. We performed enrichment analyses on differentially expressed genes to determine whether variation in aggression resembles the molecular response to infection. We further assessed whether the transcriptomic signature of aggression in the brain is similar to the neuromolecular response to acute predator threat, exposure to a high-aggression environment as an adult, or adult behavioral maturation.
Results: Across all three tissues assessed, genes that are differentially expressed as a function of aggression significantly overlap with genes whose expression is modulated by a variety of pathogens and parasitic feeding. In the fat body, and to some degree the midgut, our data specifically support the hypothesis that low aggression resembles a diseased or parasitized state. However, we find little evidence of active infection in individuals from the low aggression group. We also find little evidence that the brain molecular signature of aggression is enriched for genes modulated by social cues that induce aggression in adults. However, we do find evidence that genes associated with adult behavioral maturation are enriched in our brain samples.
Conclusions: Results support the hypothesis that low aggression resembles a molecular state of infection. This pattern is most robust in the peripheral fat body, an immune responsive tissue in the honey bee. We find no evidence of acute infection in bees from the low aggression group, suggesting the physiological state characterizing low aggression may instead predispose bees to negative health outcomes when they are exposed to additional stressors. The similarity of molecular signatures associated with the seemingly disparate traits of aggression and disease suggests that these characteristics may, in fact, be intimately tied.
Single nucleotide polymorphisms associated with postoperative inadequate analgesia after single-port VATS in Chinese population
Authors: Xing Xiufang , Bai Yongyu , Sun Kai , Yan Min 
Published: January 2020

Abstract
Background Postoperative inadequate analgesia following video-assisted thoracoscopic surgery (VATS) is a common and significant clinical problem. While genetic polymorphisms may play role in the variability of postoperative analgesia effect, few studies have evaluated the associations between genetic mutations and inadequate analgesia after single-port VATS.Methods Twenty-eight single nucleotide polymorphisms (SNPs) among 18 selected genes involved in pain perception and modulation were genotyped in 198 Chinese patients undergoing single-port VATS. The primary outcome was the occurrence of inadequate analgesia in the first night and morning after surgery which was defined by a comprehensive postoperative evaluation. Multivariable logistic regression analyses were used to identify the association between genetic variations and postoperative inadequate analgesia.Results The prevalence of postoperative inadequate analgesia was 45.5% in the present study. After controlling for age and education level, association with inadequate analgesia was observed in four SNPs among three genes encoding voltage-gated sodium channels. Patients with the minor allele of rs33985936 ( SCN11A ), rs6795970 ( SCN10A ), and 3312G>T ( SCN9A ) have an increased risk of suffering from inadequate analgesia. While the patients carrying the minor allele of rs11709492 ( SCN11A ) have lower risk experiencing inadequate analgesia.Conclusions We identified that SNPs in SCN9A , SCN10A , and SCN11A play a role in the postoperative inadequate analgesia after single-port VATS. Although future larger and long-term follow up studies are warranted to confirm our findings, the results of the current study may be utilized as predictors for forecasting postoperative analgesic effect for patients receiving this type of surgery.
Single-Stage Repair of Contaminated Hernias Using a Novel Antibiotic-Impregnated Biologic Porcine Submucosa Tissue Matrix
Authors: minor samuel fulton , Brown Carl J , Rooney Paul S , hodde jason p , julien lisa , Scott Tracy M , Karimuddin Ahmer A , Raval Manoj J , Phang Terry P 
Published: January 2020

Abstract
Background
Single-stage repair of incisional hernias in contaminated fields has a high rate of surgical site infection (30-42%) when biologic grafts are used for repair. In an attempt to decrease this risk, a novel graft incorporating gentamicin into a biologic extracellular matrix derived from porcine small intestine submucosa was developed.

Methods
This prospective, multicenter, single-arm study was designed to determine the incidence of surgical site infection following implantation of the device into surgical fields characterized as CDC Class II, III, or IV.

Results
Twenty-four patients were enrolled, with 42% contaminated and 25% dirty surgical fields. After 12 months, 5 patients experienced 6 surgical site infections (21%) with infection involving the graft in 2 patients (8%). No grafts were explanted.

Conclusions
The incorporation of gentamicin into a porcine-derived biologic graft is feasible and safe with a low rate of device infection for patients undergoing single-stage repair of ventral hernia in contaminated settings.

Trial Registration
The study was registered March 27, 2015 at www.clinicaltrials.gov as NCT02401334.

Keywords

Hernia repair; graft; abdominal wall reconstruction; contamination
Breast self-examination and associated factors among women in Wolaita sodo city, Ethiopia: Community based cross sectional study
Authors: Lera Temesgen Abiso , Beyene Aman , Bekele Befekadu , Abreha Solomon 
Published: January 2020

Abstract
Background: Early detection of breast cancer plays an important role in decreasing morbidity and mortality associated with breast cancer. Breast self-examination (BSE) is one of the screening methods for early detection of breast cancer. BSE involves the woman herself looking at and feeling each breast for possible lumps, distortions or swelling. BSE is a simple exercise which can potentially save the life of a woman but it is not well focused yet. So, this study was aimed to assess breast Self-Examination and associated factors among women in Wolaita Sodo city, Ethiopia. Methods: Community based cross-sectional study design was employed. Systematic random sampling technique was used to select 626 women aged 20-65 years old. The data were collected using pre-tested and structured questionnaire. The data was entered using Epi data version 3.5.1 and exported to SPSS version 21 software for statistical analysis. Bivariable and multiple logistic regression analysis were done.Variables with P-value less than 0.05 were considered as statically significant. Results: A total of 629 women were included in the study. More than half (60.9%) of the participants were in the age range of 20-29 years. Women who had mentioned BSE as method for early detection of breast problem were 6.36 times (AOR: 6.36, 95% CI :( 3.72, 10.71) more likely to perform BSE than those who say that they don’t know any method. Women breast feed 13-24 months were 2.43 times AOR: 2.43, 95% CI :( 1.28, 4.59) more likely to examine their breast than those who breast feed different duration. Employed women were 3.13 times more likely AOR: 3.13 95% CI :( 1.14, 8.58) to practice BSE than women not employed. Likewise being student was 3.73 times AOR: 3.73, 95% CI (1.19, 11.73) more likely to perform BSE than others. Conclusion: The finding of this study showed that women’s practice of breast self-examination is relatively low. Knowledge of BSE, breast feeding 13-24 months, being employed and being student were factors affecting performing breast self-examination. Therefore, educating girls and increasing awareness on electronics media is important.
Genetic segregation for male body coloration and female mate preference in the guppy
Authors: Sato Aya , Kawata Masakado 
Published: January 2020

Abstract
Objective The purpose of this study was to segregate the genetic lines responsible for the orange area of coloration in males and the response to orange coloration exhibited by females in the guppy ( Poecilia reticulata ) through artificial selection. This study is part of a project that uses QTL-seq to search for candidate genes involved in male orange coloration and female response to male coloration. We created two lines: high-selected lines of males having large areas of orange spots and of females with high response to male orange coloration; and low-selected lines of males having small areas of orange spots and of females with low response to male orange coloration.Results The male orange area and the female response became significantly different between high- and low-selected lines after three generations of artificial selection. This indicates that the differences in the frequencies of alleles at loci affecting the orange area and the female response between the lines increased over the generations through selection.