bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cognition and mental wellbeing after electrical accidents: a survey and a clinical study among Swedish male electricians
Authors: Thomée Sara , Österberg Kai , Rådman Lisa , Jakobsson Kristina 
Published: February 2020

Abstract
Purpose
The purpose was to examine long-term consequences of exposure to electrical current passing through the body. We investigated (1) whether electricians after having experienced an electrical accident report more cognitive problems and lower mental wellbeing and (2) have objectively verifiable reduced cognitive function; and (3) which circumstances at the time of the accident affect long-term subjective cognitive function and mental wellbeing?

Methods
A survey of male electricians who had experienced electrical accidents (n = 510) and a clinical study in a subsample (n = 23) who reported residual health problems was carried out. Both groups were examined regarding subjective cognitive function (Euroquest-9) and mental wellbeing (Symptom Checklist-90 subscales). The clinical study included neuropsychological tests of memory, attention, spatial function, and premorbid intellectual capacity. A matched control group was retrieved from reference data.

Results
The survey participants reported more cognitive problems and lower mental wellbeing than referents. Of the examined circumstances, having experienced mortal fear at the time of the accident and health complaints, especially mental symptoms, for > 1 week after the accident were the most significant risk factors for later subjective cognitive problems and lower mental wellbeing. The only statistically significant difference in neuropsychological tests was better performance in part of the memory tests by the clinical study group compared to the control group.

Conclusions
The participants reported more cognitive problems and lower mental wellbeing than referents, but no long-term objective cognitive dysfunction was detected. Emotional response at the time of the accident and health complaints in the aftermath of the accident may constitute important indications for medical and psychological follow-ups.
Distribution and development of the external sense organ pattern on the appendages of postembryonic and adult stages of the spider Parasteatoda tepidariorum
Authors: Schacht Magdalena Ines , Francesconi Martina , Stollewerk Angelika 
Published: February 2020

AbstractSpiders are equipped with a large number of innervated cuticular specializations, which respond to various sensory stimuli. The physiological function of mechanosensory organs has been analysed in great detail in some model spider species (e.g.Cupiennius salei); however, much less is known about the distribution and function of chemosensory organs. Furthermore, our knowledge on how the sense organ pattern develops on the spider appendages is limited. Here we analyse the development of the pattern and distribution of six different external mechano- and chemosensory organs in all postembryonic stages and in adult male and female spiders of the speciesParasteatoda tepidariorum. We show that except for small mechanosensory setae, external sense organs appear in fixed positions on the pedipalps and first walking legs, arranged in longitudinal rows along the proximal-distal axis or in invariable positions relative to morphological landmarks (joints, distal tarsal tip). A comparison to other Entelegynae spiders shows that these features are conserved. We hope that this study lays the foundation for future molecular analysis to address the question how this conserved pattern is generated.
Comparative multi-assay evaluation of Determine™ HIV-1/2 Ag/Ab Combo rapid diagnostic tests in acute and chronic HIV infection
Authors: Wratil Paul R. , Rabenau Holger F. , Eberle Josef , Stern Marcel , Münchhoff Maximilian , Friedrichs Imke , Stürmer Martin , Berger Annemarie , Kuttner-May Susanne , Münstermann Dieter , Lucht Andreas , Meixenberger Karolin , Bannert Norbert , Keppler Oliver T. 
Published: February 2020

AbstractIn resource-limited or point-of-care settings, rapid diagnostic tests (RDTs), that aim to simultaneously detect HIV antibodies and p24 capsid (p24CA) antigen with high sensitivity, can pose important alternatives to screen for early infections. We evaluated the performance of the antibody and antigen components of the old and novel version of the Determine™ HIV-1/2 Ag/Ab Combo RDTs in parallel to quantifications in a fourth-generation antigen/antibody immunoassay (4G-EIA), p24CA antigen immunoassay (p24CA-EIA), immunoblots, and nucleic acid quantification. We included plasma samples of acute, treatment-naïve HIV-1 infections (Fiebig stages I–VI, subtypes A1, B, C, F, CRF02_AG, CRF02_AE, URF) or chronic HIV-1 and HIV-2 infections. The tests’ antigen component was evaluated also for a panel of subtype B HIV-1 transmitted/founder (T/F) viruses, HIV-2 strains and HIV-2 primary isolates. Furthermore, we assessed the analytical sensitivity of the RDTs to detect p24CA using a highly purified HIV-1NL4-3 p24CA standard. We found that 77% of plasma samples from acutely infected, immunoblot-negative HIV-1 patients in Fiebig stages II–III were identified by the new RDT, while only 25% scored positive in the old RDT. Both RDTs reacted to all samples from chronically HIV-1-infected and acutely HIV-1-infected patients with positive immunoblots. All specimens from chronically infected HIV-2 patients scored positive in the new RDT. Of note, the sensitivity of the RDTs to detect recombinant p24CA from a subtype B virus ranged between 50 and 200 pg/mL, mirrored also by the detection of HIV-1 T/F viruses only at antigen concentrations tenfold higher than suggested by the manufacturer. The RTD failed to recognize any of the HIV-2 viruses tested. Our results indicate that the new version of the Determine™ HIV-1/2 Ag/Ab Combo displays an increased sensitivity to detect HIV-1 p24CA-positive, immunoblot-negative plasma samples compared to the precursor version. The sensitivity of 4G-EIA and p24CA-EIA to detect the major structural HIV antigen, and thus to diagnose acute infections prior to seroconversion, is still superior.
Guidelines for uveal melanoma: a critical appraisal of systematically identified guidelines using the AGREE II and AGREE-REX instrument
Authors: Steeb Theresa , Hayani Kinan M. , Förster Paul , Liegl Raffael , Toussaint Frédéric , Schlaak Max , Berking Carola , Heppt Markus V. 
Published: February 2020

Abstract
Purpose
Clinical practice guidelines provide recommendations for the management of diseases. In orphan conditions such as uveal melanoma (UM), guideline developers are challenged to provide practical and useful guidance even in the absence of high-quality evidence. Here, we assessed the methodological quality and identified deficiencies of international guidelines on UM as a base for future guideline development.

Methods
A systematic search was carried out in guideline databases, Medline and Embase until 27th May 2019 for guidelines on UM published between 2004 and 2019. Five independent reviewers assessed the methodological quality of the identified guidelines using the instruments “Appraisal of Guidelines for Research and Evaluation II” (AGREE II) and AGREE-REX (Recommendation EXcellence). Descriptive analysis was performed and subgroup differences were explored with the Kruskal–Wallis (H) test. The relationship between the individual domains and items of the instruments were examined using Spearman’s correlation.

Results
Five guidelines published from 2014 to 2018 by consortia of the United States of America, Canada and the United Kingdom (UK) were included. The highest scores were obtained by the UK guideline fulfilling 48–86% of criteria in AGREE II and 30–60% for AGREE-REX. All guidelines showed deficiencies in the domains “editorial independence”, “applicability”, and “recommendation”. Subgroup differences were identified only for the domain “editorial independence”.

Conclusion
The UK guideline achieved the highest scores with both instruments and may serve as a basis for future guideline development in UM. The domains “editorial independence”, “recommendation”, and “applicability” were identified as methodological weaknesses and require particular attention and improvement in future guidelines.
Design methodology for 360° immersive video applications: the case study of a cultural heritage virtual tour
Authors: Argyriou Lemonia , Economou Daphne , Bouki Vassiliki 
Published: February 2020

AbstractThree hundred sixty–degree (360°) immersive video applications for Head Mounted Display (HMD) devices offer great potential in providing engaging forms of experiential media solutions especially in Cultural Heritage education. Design challenges emerge though by this new kind of immersive media due to the 2D form of resources used for their construction, the lack of depth, the limited interaction and the need to address the sense of presence. In addition, the use of Virtual Reality (VR) headsets often causes nausea, or motion sickness effects imposing further implications in moderate motion design tasks. This paper introduces a methodological categorisation of tasks and techniques for the design of 360° immersive video applications. Following the design approach presented, a testbed application has been created as an immersive interactive virtual tour at the historical centre of the city of Rethymno in Crete, Greece, which has undergone user trials. Based on the analysis of the results of this study, a set of design guidelines for the implementation of 360° immersive video virtual tours is proposed.
Fast multi-language LSTM-based online handwriting recognition
Authors: Carbune Victor , Gonnet Pedro , Deselaers Thomas , Rowley Henry A. , Daryin Alexander , Calvo Marcos , Wang Li-Lun , Keysers Daniel , Feuz Sandro , Gervais Philippe 
Published: February 2020

AbstractWe describe an online handwriting system that is able to support 102 languages using a deep neural network architecture. This new system has completely replaced our previous segment-and-decode-based system and reduced the error rate by 20–40% relative for most languages. Further, we report new state-of-the-art results on IAM-OnDB for both the open and closed dataset setting. The system combines methods from sequence recognition with a new input encoding using Bézier curves. This leads to up to$$10\times $$10×faster recognition times compared to our previous system. Through a series of experiments, we determine the optimal configuration of our models and report the results of our setup on a number of additional public datasets.
Expressions of collective grievance as a feedback in multi-actor adaptation to water risks in Mexico City
Authors: Eakin Hallie , Shelton Rebecca , Baeza Andrés , Bojórquez-Tapia Luis A. , Flores Shalae , Parajuli Jagadish , Grave Ileana , Estrada Barón Alejandra , Hernández Bertha 
Published: February 2020

AbstractEffective adaptation assumes a feedback between the experience or anticipation of harm, and the actions of those individuals whose decisions and actions are necessary to reduce that harm. In urban areas, citizens often expect support from the public sector to facilitate their adaptation efforts and to protect them from exposure. This expectation—grounded in notions of the social contract between citizens and the state—presumes efficient feedback between public sector actors and residents concerning vulnerable states and adaptation needs. Through a case study of Mexico City, we analyze the role of social mobilization, specifically, neighborhood protests associated with water scarcity, as an informal means for a vulnerable population to communicate its needs to those actors with the mandate and capacity to alter risk exposure. On the basis of the findings from the case study, we propose a simple framework to begin a more systematic process of analyzing the expression of grievances as a feedback among actors involved in urban adaptation. We argue that by making visible these expressions as an informal mechanism of feedback between risk exposure, impact, decision-making, and the biophysical environment, we can reveal a potentially important lever on system change: one that highlights existing asymmetries in power, equity, and rights in urban adaptation.
Teacher burnout profiles and proactive strategies
Authors: Pyhältö Kirsi , Pietarinen Janne , Haverinen Kaisa , Tikkanen Lotta , Soini Tiina 
Published: February 2020

AbstractTeacher burnout has been identified as a significant occupational hazard. However, our understanding about individual variations in burnout risk among in-service teachers is still less than sufficient. This study explored socio-contextual burnout risk profiles and their association with the reported use of proactive strategies among in-service teachers by using a person-oriented approach. The survey data were collected from 2310 Finnish in-service primary and lower secondary school teachers using a probability sampling method. In the latent profile analysis, five socio-contextual burnout profiles were identified. The profiles differed from each other in terms of burnout symptoms and proactive strategy use. Results suggested that there is individual variation in teachers’ risk of burnout. In addition, the results imply that well-developed proactive strategies, both in terms of self- and co-regulative strategies, are related to lower risk of experiencing socio-contextual burnout. The utilization of strong co-regulative strategies was related to lower risk of experiencing exhaustion and inadequacy during teacher-pupil interactions. However, strong self-regulation combined with low levels of co-regulation was related to an increased risk of experiencing cynicism. This implies that learning proactive strategies may be useful in preventing teacher burnout.
Alien species and the EU Water Framework Directive: a comparative assessment of European approaches
Authors: Boon Philip J. , Clarke Stacey A. , Copp Gordon H. 
Published: February 2020

AbstractAlthough the European Water Framework Directive (WFD) does not refer explicitly to alien species (AS), it is clear that invasive AS (IAS) are considered a pressure on WFD water bodies. This article discusses the results of a questionnaire sent to all EU Member States, demonstrating considerable variability in the way that AS data are used in implementing the WFD. Responses were received from 18 countries.
Most countries define AS in a similar way, but there are discrepancies, for example, in the use of historical dates to determine whether or not a species is considered non-native biogeographically. All countries have developed lists of AS, but those specific for WFD assessments are only used at present in the UK and the Republic of Ireland.
Few countries monitor AS specifically for the WFD, or assess the risk that IAS are likely to cause water bodies to fail to achieve Good Ecological Status. This article discusses the results of a questionnaire sent to all EU Member States, demonstrating considerable variability in the way that AS data are used in implementing the WFD. Perhaps the most important difference among countries is in the use of AS data in WFD classification; many countries assume that classification methods take account of the impacts of AS, whereas separate ‘downgrading’ procedures that modify classification based on the presence and impact of IAS are used more rarely. New approaches merit further consideration, such as the application of ‘biopollution indices’ to highlight the impact of AS without affecting WFD classification. Alien species feature to some extent in river basin management plans, but more emphasis on action is needed. In addition, closer links with the Marine Strategy Framework Directive and with the 2014 EU Regulation on alien species are required to improve the control of aquatic AS.
Cellulose from the green macroalgae Ulva lactuca: isolation, characterization, optotracing, and production of cellulose nanofibrils
Authors: Wahlström Niklas , Edlund Ulrica , Pavia Henrik , Toth Gunilla , Jaworski Aleksander , Pell Andrew J. , Choong Ferdinand X. , Shirani Hamid , Nilsson K. Peter R. , Richter-Dahlfors Agneta 
Published: February 2020

Abstract
We report (1) successful extraction and characterization of cellulose from northern hemisphere green macroalgae Ulva lactuca (Ulva fenestrata) collected along the Swedish west coast and cultivated indoors under controlled conditions, followed by (2) its utilization in the production of lignin-free cellulose nanofibrils (CNF). Cellulose was extracted by sequential treatment with ethanol, hydrogen peroxide, sodium hydroxide, and hydrochloric acid, yielding a cellulose-rich insoluble fraction. The extracted cellulose was disintegrated into CNF using a mechanical homogenization process without any further enzymatic pre-treatments. In addition, regenerated cellulose was prepared. XRD characterization of the CNF showed characteristic peaks for the cellulose I allomorph and confirmed that the nanofibrils were semicrystalline with a crystallinity index of 48%. Regenerated cellulose was mostly amorphous with an XRD pattern indicating the presence of the cellulose II allomorph. The cellulose fractions were essentially free from inorganic substances and thermally stable up to around 260 °C. Structural mapping with CP-MAS 13C-NMR sustains the cellulose content of CNF and regenerated cellulose, respectively, yet ion chromatography identified the presence of 10–15% xylose in the fractions. Optotracing was used as a novel and non-disruptive tool to selectively assess the polysaccharide composition of the cellulose fractions and produced CNF aiming to shed light on this hitherto non-resolved origin of xylose in Ulva cell wall matter. Fluorescence excitation and emission spectra of a panel of 4 oligothiophenes identified and verified the presence of cellulose and sustain the conclusion that the isolated fractions consist of cellulose intertwined with a small amount of a xylose-containing glucan copolymer.

Graphic abstract
Growth of PbBr2 microrods with unique structure and surface morphology
Authors: Ahmad Zubair , Mishra Arti 
Published: February 2020

AbstractWe describe an innovative method to fabricate the one-dimensional (1D) microrods of lead bromide (PbBr2). The microrods possess unique structural and morphological properties. XRD, FESEM and HRTEM analysis exhibited a well-ordered growth and a crack-free arrangement of the microcrystals in rod shapes. XPS, Raman and FTIR studies were performed to investigate the composition and chemical structure of the rods. TGA and DSC investigations were made to investigate the thermal stability of microrods. The growth of these unique 1D microrods represents an innovative concept in material design and synthesis, which can foster a revolutionary research in the field of perovskite crystals.
Bilingualism Is Associated with a Delayed Onset of Dementia but Not with a Lower Risk of Developing it: a Systematic Review with Meta-Analyses
Authors: Brini Stefano , Sohrabi Hamid R. , Hebert Jeffrey J. , Forrest Mitchell R. L. , Laine Matti , Hämäläinen Heikki , Karrasch Mira , Peiffer Jeremiah J. , Martins Ralph N. , Fairchild Timothy J. 
Published: February 2020

AbstractSome studies have linked bilingualism with a later onset of dementia, Alzheimer’s disease (AD), and mild cognitive impairment (MCI). Not all studies have observed such relationships, however. Differences in study outcomes may be due to methodological limitations and the presence of confounding factors within studies such as immigration status and level of education. We conducted the first systematic review with meta-analysis combining cross-sectional studies to explore if bilingualism might delay symptom onset and diagnosis of dementia, AD, and MCI. Primary outcomes included the age of symptom onset, the age at diagnosis of MCI or dementia, and the risk of developing MCI or dementia. A secondary outcome included the degree of disease severity at dementia diagnosis. There was no difference in the age of MCI diagnosis between monolinguals and bilinguals [mean difference: 3.2; 95% confidence intervals (CI): −3.4, 9.7]. Bilinguals vs. monolinguals reported experiencing AD symptoms 4.7 years (95% CI: 3.3, 6.1) later. Bilinguals vs. monolinguals were diagnosed with dementia 3.3 years (95% CI: 1.7, 4.9) later. Here, 95% prediction intervals showed a large dispersion of effect sizes (−1.9 to 8.5). We investigated this dispersion with a subgroup meta-analysis comparing studies that had recruited participants with dementia to studies that had recruited participants with AD on the age of dementia and AD diagnosis between mono- and bilinguals. Results showed that bilinguals vs. monolinguals were 1.9 years (95% CI: −0.9, 4.7) and 4.2 (95% CI: 2.0, 6.4) older than monolinguals at the time of dementia and AD diagnosis, respectively. The mean difference between the two subgroups was not significant. There was no significant risk reduction (odds ratio: 0.89; 95% CI: 0.68–1.16) in developing dementia among bilinguals vs. monolinguals. Also, there was no significant difference (Hedges’g = 0.05; 95% CI: −0.13, 0.24) in disease severity at dementia diagnosis between bilinguals and monolinguals, despite bilinguals being significantly older. The majority of studies had adjusted for level of education suggesting that education might not have played a role in the observed delay in dementia among bilinguals vs. monolinguals. Although findings indicated that bilingualism was on average related to a delayed onset of dementia, the magnitude of this relationship varied across different settings. This variation may be due to unexplained heterogeneity and different sources of bias in the included studies. Registration: PROSPERO CRD42015019100.
GangstaLife: Fusing Urban Ethnography with Netnography in Gang Studies
Authors: Urbanik Marta-Marika , Roks Robert A. 
Published: February 2020

AbstractRecent research on street-involved populations has documented their online presence and has highlighted the effects of their online presentations on their lives in the real world. Given the increasing conflation between the online and offline world, contemporary urban ethnographers should pay increased attention to their participants’ online presence and interactions. However, methodological training of this sort is still in its infancy stages and has not yet evolved to guide the growing number of researchers undertaking this form of research. This article draws from our experiences using social media in our urban ethnographies with criminally involved groups, to examine the benefits, risks, and challenges of drawing on social media in urban ethnography. It is intended to serve as a foundational piece that will hopefully ignite scholarly dialogue, debate, and methodological training relating to deploying social media in urban—and specifically—gang ethnography.