bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kinetic Study of Degradation of Basic Turquise Blue X-GB and Basic Blue X-GRRL using Advanced Oxidation Process
Authors: Khan Naeem-Ul-Haq , Bhatti Haq Nawaz , Iqbal Munawar , Nazir Arif , Ain Hiratul 
Published: October 2019

Abstract
This study focuses on application of advanced oxidation (Photo-Fenton) processes to decolorize Basic Turquise Blue (BTB) X-GB 250% and Basic Blue (BB) X-GRRL 250% dyes. The percent decolorization was studied in terms of effect of variation in intensity of UV light at optimum conditions of all the parameters (pH = 3.0, H2O2 = 4.8 mM, FeSO4 = 1.6 mM, temperature = 50 °C, time = 80 min for BTB X-GB, and pH = 5.0, H2O2 = 5.6 mM, FeSO4 = 2.0 mM, temperature = 40 °C, time = 60 min for BB X-GRRL). Maximum decolorization was obtained at maximum intensity (15660 counts/min) of UV light as 96.17% for BTB X-GB and 88.48% for BB X-GRRL. First order, 2nd order and BMG kinetic models were used to analyze the data obtained for intensity of UV light. BMG model gives us the higher values of correlation coefficients for all data of both the dyes. The results have shown that Photo-Fenton oxidation process is the beneficial and effective for oxidation treatment of waste water effluents containing dyes as main pollutants.
Preparation of Ginger Oil in Water Nanoemulsion Using Phase Inversion Composition Technique: Effects of Stirring and Water Addition Rates on their Physico-Chemical Properties and Stability
Authors: Farshbaf-Sadigh Ashraf , Jafarizadeh-Malmiri Hoda , Anarjan Navideh , Najian Yahya 
Published: October 2019

Abstract
Ginger oil in water (O/W) nanoemulsions, were produced using phase inversion composition method and Tween 80, as emulsifier. Effects of processing parameters namely, stirring rate (100 to1000 rpm) and water addition rate (1–10 mL/min) were evaluated on the physico-chemical, morphological, antioxidant and antimicrobial properties of the prepared O/W nanoemulsions using response surface methodology (RSM). Results indicated that well dispersed and spherical ginger nanodroplets were formed in the nanoemulsions with minimum particle size (8.80 nm) and polydispersity index (PDI, 0.285) and maximum zeta potential value (−9.15 mV), using stirring rate and water addition rate of 736 rpm and 8.18 mL/min, respectively. Insignificant differences between predicted and experimental values of the response variables, indicated suitability of fitted models using RSM. Mean particle size of the prepared nanoemulsion using optimum conditions were changed from 8.81 ± 1 to 9.80 ± 1 nm, during 4 weeks of storage, which revealed high stability of the resulted ginger O/W nanoemulsion. High antioxidant activity (55.4%), bactericidal (against Streptococcus mutans) and fungicidal (against Aspergillus niger) activities of the prepared nanoemulsion could be related to the presence of gingerols and shogaols, a group of phenolic alkanones, in the ginger oil, which those were detected by gas chromatography method.
Prevalence of endocrine disorders in obese patients: systematic review and meta-analysis
Authors: van Hulsteijn L T , Pasquali R , Casanueva F , Haluzik M , Ledoux S , Monteiro M P , Salvador J , Santini F , Toplak H , Dekkers O M 
Published: October 2019

Objective
The increasing prevalence of obesity is expected to promote the demand for endocrine testing. To facilitate evidence guided testing, we aimed to assess the prevalence of endocrine disorders in patients with obesity. The review was carried out as part of the Endocrine Work-up for the Obesity Guideline of the European Society of Endocrinology.

Design
Systematic review and meta-analysis of the literature.

Methods
A search was performed in MEDLINE, EMBASE, Web of Science and COCHRANE Library for original articles assessing the prevalence of hypothyroidism, hypercortisolism, hypogonadism (males) or hyperandrogenism (females) in patients with obesity. Data were pooled in a random-effects logistic regression model and reported with 95% confidence intervals (95% CI).

Results
Sixty-eight studies were included, concerning a total of 19.996 patients with obesity. The pooled prevalence of overt (newly diagnosed or already treated) and subclinical hypothyroidism was 14.0% (95% CI: 9.7–18.9) and 14.6% (95% CI: 9.2–20.9), respectively. Pooled prevalence of hypercortisolism was 0.9% (95% CI: 0.3–1.6). Pooled prevalence of hypogonadism when measuring total testosterone or free testosterone was 42.8% (95% CI: 37.6–48.0) and 32.7% (95% CI: 23.1–43.0), respectively. Heterogeneity was high for all analyses.

Conclusions
The prevalence of endocrine disorders in patients with obesity is considerable, although the underlying mechanisms are complex. Given the cross-sectional design of the studies included, no formal distinction between endocrine causes and consequences of obesity could be made.
Effect of Compensation Degree on the Detecting Properties of In-doped Cd0.9Zn0.1Te crystals
Authors: Sklyarchuk V.M. , Zakharuk Z.I. , Kolisnyk M.H. , Rarenko А.I. , Sklyarchuk O.F. , Fochuk P.M. 
Published: October 2019

The electrical characteristics of In-doped Cd0.9Zn0.1Te (CZT:In) crystals with concentration of Со = 3,5×1017 cm-3, which are used in X- and gamma-radiation detectors, were investigated. CZT:In crystals possess a weakly pronounced n-type conductivity and had a resistivity of (1 ¸ 2)*109 Ohm´cm at 293 K. In/CZT:In/In structures with ohmic contacts and Cr/CZT:In/In structures with Schottky barriers were created on their base. The temperature dependences of the resistivity in investigated material were analyzed and explained. The energy position of the deep level responsible for the material’ dark conductivity was found. Due to the study of the temperature dependencies of currents limited by space-charge and of currents of the ohmic section of the volt-ampere characteristics (I-VC), the compensation degree of CZT:In crystals is determined. It was found that Cr/CZT:In/In structures with a Schottky diode, fabricated on crystals with a lower compensation degree, possessed the best detection properties than similar structures fabricated on crystals with a greater compensation degree.
Identification of Genes Required for Apical Protein Trafficking inDrosophilaPhotoreceptor Cells
Authors: Laffafian Azadeh , Tepass Ulrich 
Published: October 2019

AbstractDrosophila melanogaster photoreceptor cells are highly polarized epithelial cells. Their apical membrane is further subdivided into the stalk membrane and the light-sensing rhabdomere. The photo-pigment Rhodopsin1 (Rh1) localizes to the rhabdomere, whereas the apical determinant Crumbs (Crb) is enriched at the stalk membrane. The proteoglycan Eyes shut (Eys) is secreted through the apical membrane into an inter-rhabdomeral space. Rh1, Crb, and Eys are essential for the development of photoreceptor cells, normal vision, and photoreceptor cell survival. Human orthologs of all three proteins have been linked to retinal degenerative diseases. Here, we describe an RNAi-based screen examining the importance of 237 trafficking-related genes in apical trafficking of Eys, Rh1, and Crb. We found 28 genes that have an effect on the localization and/or levels of these apical proteins and analyzed several factors in more detail. We show that the Arf GEF protein Sec71 is required for biosynthetic traffic of both apical and basolateral proteins, that the exocyst complex and the microtubule-based motor proteins dynein and kinesin promote the secretion of Eys and Rh1, and that Syntaxin 7/Avalanche controls the endocytosis of Rh1, Eys, and Crb.
Integrin-Linked Kinase Deficiency in Collecting Duct Principal Cell Promotes Necroptosis of Principal Cell and Contributes to Kidney Inflammation and Fibrosis
Authors: Huang Ming , Zhu Shuai , Huang Huihui , He Jinzhao , Tsuji Kenji , Jin William W. , Xie Dongping , Ham Onju , Capen Diane E. , Lu Weining , Păunescu Teodor G. , Yang Baoxue , Lu Hua A. Jenny 
Published: October 2019

Significance Statement
Necroptosis has emerged as an important cell death pathway that contributes to inflammation and injury of many organs, including the kidney. The mechanisms underlying necroptosis are not well understood. The authors have identified a previously unrecognized important role of integrin-linked kinase (ILK) in mediating necroptosis in collecting duct epithelial cell using genetically engineered mice to lack Ilk in the collecting duct principal cells of the kidney. These Ilk-knockout mice develop acute tubular injury, interstitial fibrosis and inflammation in the kidneys. Treating both the ILK inhibited cultured cells and ILK-deficient mice with a necroptosis inhibitor, necrostatin-1, reduced the harmful effects associated with the loss of ILK. The study shows that ILK plays an important role in regulating necroptosis in kidney tubular cells.

Background
Necroptosis is a newly discovered cell death pathway that plays a critical role in AKI. The involvement of integrin-linked kinase (ILK) in necroptosis has not been studied.

Methods
We performed experiments in mice with an Ilk deletion in collecting duct (CD) principal cells (PCs), and cultured tubular epithelial cells treated with an ILK inhibitor or ILK siRNA knockdown.

Results

Ilk deletion in CD PCs resulted in acute tubular injury and early mortality in mice. Progressive interstitial fibrosis and inflammation associated with the activation of the canonical TGF-β signaling cascade were detected in the kidneys of the mice lacking ILK in the CD PCs. In contrast to the minimal apoptosis detected in the animals’ injured CDs, widespread necroptosis was present in ILK-deficient PCs, characterized by cell swelling, deformed mitochondria, and rupture of plasma membrane. In addition, ILK deficiency resulted in increased expression and activation of necroptotic proteins MLKL and RIPK3, and membrane translocation of MLKL in CD PCs. ILK inhibition and siRNA knockdown reduced cell survival in cultured tubular cells, concomitant with increased membrane accumulation of MLKL and/or phospho-MLKL. Administration of a necroptosis inhibitor, necrostatin-1, blocked cell death in vitro and significantly attenuated inflammation, interstitial fibrosis, and renal failure in ILK-deficient mice.

Conclusions
The study demonstrates the critical involvement of ILK in necroptosis through modulation of the RIPK3 and MLKL pathway and highlights the contribution of CD PC injury to the development of inflammation and interstitial fibrosis of the kidney.
K-boyutlu ağaç ve uyarlanabilir yarıçap (KD-AR Stream) tabanlı gerçek zamanlı akan veri kümeleme
Authors: ŞENOL Ali , KARACAN Hacer 
Published: October 2019

Akan veri kümeleme, teknolojik
gelişmelere paralel olarak veri miktarının inanılmaz boyutlara ulaştığı
gümünüzün popüler konularından biridir. Akan veri kümeleme yaklaşımlarında
karşılaşılan en önemli problemler çoğu yaklaşımın çevrimiçi ve çevrimdışı
evreden oluşması, küme sayısını tanımlama veya bu sayıya bir sınır koyma
zorunluluğu, en doğru yarıçap değerini belirlemede yaşanan problemler ve
önerilen modellerin kendisini gelen yeni verilere adapte etmesinde (concept
evolution) yaşanan problemlerdir. Bu
problemlerin yanında, neredeyse bu alandaki bütün çalışmaların sayısal miktar
tabanlı bir özetleme yapması da bazı uygulamalar için ihtiyacı
karşılamamaktadır. Oysa son 1 saniyede veya son 1 saatte gelen veriler şeklinde
çalışan zaman tabanlı bir özetleme yaklaşımına da ihtiyaç vardır. Bu çalışmada,
K-boyutlu ağaç, uyarlanabilir yarıçap tabanlı (KD-AR Stream) ve kümeleme
adaptasyonu özelliğine sahip gerçek zamanlı akan verileri kümeleyen bir
yaklaşım önerilmektedir. Önerdiğimiz yöntem SE-Stream, DPStream ve CEDAS
algoritmaları ile hem kümeleme başarısı hem de işlem performansı açısından
karşılaştırılmıştır. Elde edilen sonuçlar KD-AR Stream algoritmasının diğer
algoritmalara göre yüksek bir kümeleme başarısını makul bir sürede
gerçekleştirdiğini göstermektedir.
Trabzon - Giresun arasında bulunan fındık bahçelerinde bazı ağır metallerin (Cr, Ni, Pb) tespiti ve değerlendirilmesi
Authors: PEHLİVAN Engin , ASLANTAŞ Rafet 
Published: October 2019

Bu
çalışma, fındık tarımının yoğun olarak yapıldığı Trabzon ve Giresun il
merkezleri arasında belirlenen fındık bahçelerinden alınan bitki örnekleri üzerinde
gerçekleştirilmiştir. Bu bahçeler, on
farklı lokasyon ve her lokasyonda üç farklı rakım aralıklarından oluşmaktadır. Bitki
örnekleri; aynı bahçedeki bitkilerden alınan yaprak, züruf, sert kabuk ve iç
meyveden (fındık) oluşmuştur. Bu örneklerdeki ağır metaller (Cr, Ni, Pb)
incelenmiştir. Örneklerdeki ağır metal içerikleri Yaş yakma tekniği uygulanarak
ISP-OES cihazında belirlenmiştir. Bitki örneklerinde Cr 0.21 – 2.09 ppm, Ni
3.58 – 7.33 ppm, Pb 0.29 – 1.70 ppm arasında tespit edilmiştir. Ağır metal
içeriği bakımından incelenen bitki örneklerinde, hem lokasyonlar arasında hem
de kollar arasında önemli farklar olduğu belirlenmiş, bu durum günümüzde ve
gelecekte önemli riskler taşıdığını göstermiştir.
Breaching the walls of academe: the case of five Afro-Caribbean immigrant women within United States institutions of higher education
Authors: Esnard Talia Randa 
Published: October 2019

While a growing tendency among researchers has been for the examination of diverse forms of discrimination against Afro-Caribbean immigrants within the United States (US), the types of ambiguities that these create for framing the personal and professional identities of Afro-Caribbean women academics who operate within that space remain relatively absent. The literature is also devoid of substantive explorations that delve into the ways and extent to which the cultural scripts of Afro-Caribbean women both constrain and enable their professional success in academe. The call therefore is for critical examinations that deepen, while extending existing examinations of the lived realities for Afro-Caribbean immigrants within the US, and, the specific trepidations that they both confront and overcome in the quest for academic success while in their host societies. Using intersectionality as the overarching framework for this work, we demonstrate, through the use of narrative inquiry, the extent to which cultural constructions of difference nuance the social axes of power, the politics of space and identity, and professional outcomes of Afro-Caribbean immigrant women who operate within a given context. These are captured within our interrogation of the structures of power that they confront and their use of culture to fight against and to break through institutional politics.
Musicogramas para la interculturalidad: ¿Estamos preparados en Educación Primaria? / Musicograms for interculturality: are we prepared in primary education?
Authors: Azorín-Delegido José Manuel , Bernabé Villodre Mª del Mar 
Published: October 2019

La especial idiosincrasia autonómica de España facilita la inclusión de músicas de otras culturas, que puede contribuir a favorecer la inclusión del alumnado hijo de inmigrantes. Se pretende mostrar cómo el profesorado de Primaria puede tener dificultades para educar interculturalmente, porque sus materiales no facilitan la comprensión de la alteridad cultural. Se ha realizado un estudio cuantitativo y cualitativo centrado en revistas de temática musical. Un escaso número de revistas musicales han dedicado espacio a los musicogramas, que no se adecúan a la realidad pluricultural española. Los datos obtenidos demostraron que los materiales de uso didáctico no se adaptan a las necesidades interculturales del alumnado.
A comparative study of RIPASA score and modified Alvarado score in diagnosis of acute appendicitis
Authors: El Sherpiny Waleed Yusif 
Published: October 2019

Background: Various diagnostic criteria have been described for diagnosing acute appendicitis. Of these, Alvarado score has been the most commonly used. The RIPASA score is a new diagnostic scoring system developed for the diagnosis of acute appendicitis and showed higher sensitivity, specificity and diagnostic accuracy as compared to Alvarado score. we want to compare prospectively Alvarado and RIPASA score by applying them to patients attending emergency department complaining of right iliac fossa pain that could probably be acute appendicitis.Methods: Patients with clinically suspected acute appendicitis were classified according to both Alvarado and RIPASA scoring systems before undergoing surgery. Histopathological examination of the removed appendix was taken as the gold standard for diagnosis of acute appendicitis.Results: Among (90%) patients had histologically confirmed appendicitis. With the cut-off value greater than 7.5 for RIPASA score; sensitivity, specificity, positive predictive value, negative predictive value, diagnostic accuracy were 88.2%, 14.5%, 73.1%, 32%,and 68% respectively. With the cut-off value greater than 7 for Alvarado score, sensitivity, specificity, positive predictive value, negative predictive value, diagnostic accuracy and negative appendectomy rates were 51.2%, 80 %, 91 %, 29%, and 57%, respectively. 87.5% of patients were correctly stratified by RIPASA under higher probability group while only 45% were classified by Alvarado as high probability.Conclusions: RIPASA scoring system showed high sensitivity and diagnostic accuracy in comparison to Alvarado scoring system. So, it can be applied for the diagnosis of acute appendicitis.
Knowledge, attitude and practices regarding work related hazards among salt workers in Marakkanam, Tamil Nadu
Authors: Cherian Johnson , Singh Zile , Bazroy Joy , Purty Anil J. , Natesan Murugan 
Published: October 2019

Background: The salt pan workers are exposed to severe health hazards like extreme heat, intense manual labour, direct contact with salt, sunlight glare from salt crystals. This paper describes their knowledge, attitude and practices (KAP) regarding their work related hazards as well as availability and use of personal protective equipments (PPEs).Methods: A community based cross sectional study was conducted in 4 randomly selected villages among the 10 salt worker villages in Marakkanam, Tamil Nadu. A house to house survey of the selected villages enrolled 331 salt workers. The data was collected using a pre designed and pre tested questionnaire.Results: Majority of salt worker (78.5%) reported of being aware of one or more hazards like physical stress (70.7%), direct sunlight (38.7%) and glare from salt crystals (16%) in salt work that resulted in musculoskeletal problems, ophthalmic problems, headache and giddiness. 87% of the salt workers were aware of one or the other personal protective equipments. However, only less than 10% were using the conventional PPEs. The reasons for not using PPE were mainly inconvenience in using and PPE not provided by the employer.Conclusions: Most of the study population is aware of the hazards as well as one or the other methods of protective equipment but actual use of PPE is very low because of non-availability and perception of inconvenience in using them. There is a large gap between awareness and practice regarding PPE usage among these salt workers.
TREATMENT MANAGEMENT OF PATIENTS WITH MANDIBULAR MICROGNATHIA AND RETROGNATHISM IN INCOMPLETED FACIAL SKELETON GROWTH PERIOD
Authors: Меграбян Ольга , Megrabyan Olga , Ишмурзин Павел , Ishmurzin Pavel 
Published: October 2019

Importance. The choice of management and orthodontic appliance construction is fundamental in planning and treatment of patients with mandibular micrognathia and/ or retrognathism.
The aim ― is evaluation of treatment effectiveness of patients with mandibular micrognathia and/ or retrognathism in incompleted facial skeleton growth period.
Methodoloty. Base of the research was Children dentistry and orthodontics department of E.A. Vagner Perm State Medical University. The object of the research is 98 patients aged from 5,5 to 16 (42 girls and 56 boys) with distal occlusion and mandibular micrognathia and/ or retrognathism. Data for study were lateral cephalograms, profile images, clinical study results before and after orthodontic treatment.
Results. It was determined that the largest increase in mandible size and its position normalization is observed in the treatment of patients with CS2, CS3 cervical vertebral maturation stages. In patients with CS5 cervical vertebral maturation stage and overjet more than 6 mm we use a symptomatic treatment principle for distal occlusion correction.
Results application area ― orthodontists practice.
Conclusions. This data may be used in prognosis of orthodontic treatment outcome and retentional period in patients with distal occlusion.
PARTICIPATION OF CIVIL SOCIETY IN PUBLIC ADMINISTRATION: PROSPECTS FOR INTERNATIONAL EXPERIENCE IMPLEMENTATION IN UKRAINE
Authors: Bila-Tiunova Liubov , Bilous-Osin Tetiana , Kozachuk Diana , Vasylkivska Victoriia 
Published: October 2019

Purpose: Determination of possible ways to increase the effectiveness of interaction between civil society institutions and public administration subjects in Ukraine through the use of international experience; determination of a unified concept of management humanization and democratization and proposal of specific recommendations for reforming the existing public administration system in Ukraine.
Methodology: General and specific methods of scientific knowledge were applied during the research: a system analysis method, a dialectical method, a formal-logical method, a structural-functional method, and empirical methods.
Result: The authors concluded that there is poor interaction between the public administration subjects and the civil society institutions in Ukraine. In order to increase the positive effect of introducing new forms of civil participation in public administration, it is important to popularize citizens’ e-participation in public administration. Free access to the electronic reflection of activities of any public administration subject allows simplifying public participation in making specific decisions.
Applications: The results of the research are believed to be interesting and useful for domestic legislators and public administration subjects at actualization of tendencies to administration democratization and humanization.
Novelty/Originality: The results are obtained independently and original (no analogues or incorrect borrowings). The research subject is considered in Ukraine for the first time and seems to be prospective for further development.