bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constrictive Pericarditis Associated with Coronavirus Disease 2019 (COVID-19): A Case Report
Authors: SeyedAlinaghi SeyedAhmad , Ghadimi Maryam , Gharabaghi Mehrnaz Asadi , Ghiasvand Fereshteh 
Published: December 2020

Background:
Since December 2019, there has been an increasing number of patients infected
with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) around the world.
As of March 2020, the World Health Organization declared a global pandemic.

Case Presentation:
To our best knowledge, this is the first report of a patient with SARS-CoV-2 infection
presenting with constrictive pericarditis, possibly from the COVID infection. She was presented
after a week of fever, persistent dry cough, and diarrhea. She received a single dose of hydroxychloroquine
400 mg, Oseltamivir 75 mg every 12 hours, lopinavir/ritonavir (Kaletra) 400/100
mg every 12 hours, and levofloxacin 750 mg daily. After 24 hours, she was immediately transferred
to the Intensive Care Unit (ICU) because of dyspnea and progressive respiratory failure with
a drop of the O2 saturation to 70%.

Conclusion:
After a week of progress, her respiratory condition deteriorated again. She was re-admitted
to the ICU and she expired. She died due to constrictive pericarditis, most probably caused
by SARS-CoV-2.
Liver-Brain Axis in Sporadic Alzheimer’s Disease: Role of Ten Signature Genes in a Mouse Model
Authors: Jakhmola-Mani Ruchi , Islam Anam , Katare Deepshikha Pande 
Published: December 2020

Aim:
Poor nutritional effect of junk food induces injuries to the liver and the brain but
still most of the developing nations survive on these diets to compensate for the fast-paced
lifestyle. The aim of the study is to infer the protein-connections behind the liver-brain axis and
identify the role of these proteins in causing neurodegenerative disorders.

Background:
Chronic consumption of fructose and fat-rich food works as a toxin in the body and
has the ability to cause a negative metabolic shift. Recently a study was published in Annals of Internal
Medicine (2019) citing the loss of vision and hearing in a 14-year-old boy whose diet was
strictly restricted to fries and junk-food for almost a decade. This puts the entire body on insulin resistance
and related co-morbidities and causes simultaneous damaging effects on the liver as well
as the brain. This work provides insights into the liver-brain axis and explains how the liver is involved
in brain related disorders.

Objective:
In this study, transcriptomic data related to chronic eating of junk-food was analyzed
and simultaneous damage that happens in the liver and the brain was assessed at the molecular
level.

Method:
Transcriptomic study was taken from the GEO database and analysed to find out the
genes dysregulated in both the liver and the brain during this metabolic stress. Cytoscapev3.7 was
used to decipher the signalling between the liver and the brain. This connection between both is
called as the liver-brain axis.

Results:
The results obtained from our study indicate the role of TUBB5-HYOU1-SDF2L1-DECR1-
CDH1-EGFR-SKP2-SOD1-IRAK1-FOXO1 gene signature in the decline of concurrent liver
and brain health. Dysregulated levels of these genes are linked to molecular processes like cellular
senescence, hypoxia, glutathione synthesis, amino acid modification, increased nitrogen content,
synthesis of BCAAs, cholesterol biosynthesis, steroid hormone signalling and VEGF pathway.

Conclusion:
The results obtained from our study indicate the role of TUBB5-HYOU1-SDF2L1-DECR1-
CDH1-EGFR-SKP2-SOD1-IRAK1-FOXO1 gene signature in the decline of concurrent liver
and brain health. Dysregulated levels of these genes are linked to molecular processes like cellular
senescence, hypoxia, glutathione synthesis, amino acid modification, increased nitrogen content,
synthesis of BCAAs, cholesterol biosynthesis, steroid hormone signalling and VEGF pathway.
A Chatbot for Perinatal Women’s and Partners’ Obstetric and Mental Health Care: Development and Usability Evaluation Study
Authors: Chung Kyungmi , Cho Hee Young , Park Jin Young 
Published: December 2020

Background
To motivate people to adopt medical chatbots, the establishment of a specialized medical knowledge database that fits their personal interests is of great importance in developing a chatbot for perinatal care, particularly with the help of health professionals.

Objective
The objectives of this study are to develop and evaluate a user-friendly question-and-answer (Q&A) knowledge database–based chatbot (Dr. Joy) for perinatal women’s and their partners’ obstetric and mental health care by applying a text-mining technique and implementing contextual usability testing (UT), respectively, thus determining whether this medical chatbot built on mobile instant messenger (KakaoTalk) can provide its male and female users with good user experience.

Methods
Two men aged 38 and 40 years and 13 women aged 27 to 43 years in pregnancy preparation or different pregnancy stages were enrolled. All participants completed the 7-day-long UT, during which they were given the daily tasks of asking Dr. Joy at least 3 questions at any time and place and then giving the chatbot either positive or negative feedback with emoji, using at least one feature of the chatbot, and finally, sending a facilitator all screenshots for the history of the day’s use via KakaoTalk before midnight. One day after the UT completion, all participants were asked to fill out a questionnaire on the evaluation of usability, perceived benefits and risks, intention to seek and share health information on the chatbot, and strengths and weaknesses of its use, as well as demographic characteristics.

Results
Despite the relatively higher score of ease of learning (EOL), the results of the Spearman correlation indicated that EOL was not significantly associated with usefulness (ρ=0.26; P=.36), ease of use (ρ=0.19; P=.51), satisfaction (ρ=0.21; P=.46), or total usability scores (ρ=0.32; P=.24). Unlike EOL, all 3 subfactors and the total usability had significant positive associations with each other (all ρ>0.80; P<.001). Furthermore, perceived risks exhibited no significant negative associations with perceived benefits (ρ=−0.29; P=.30) or intention to seek (SEE; ρ=−0.28; P=.32) or share (SHA; ρ=−0.24; P=.40) health information on the chatbot via KakaoTalk, whereas perceived benefits exhibited significant positive associations with both SEE and SHA. Perceived benefits were more strongly associated with SEE (ρ=0.94; P<.001) than with SHA (ρ=0.70; P=.004).

Conclusions
This study provides the potential for the uptake of this newly developed Q&A knowledge database–based KakaoTalk chatbot for obstetric and mental health care. As Dr. Joy had quality contents with both utilitarian and hedonic value, its male and female users could be encouraged to use medical chatbots in a convenient, easy-to-use, and enjoyable manner. To boost their continued usage intention for Dr. Joy, its Q&A sets need to be periodically updated to satisfy user intent by monitoring both male and female user utterances.
mHealth-Supported Delivery of an Evidence-Based Family Home-Visiting Intervention in Sierra Leone: Protocol for a Pilot Randomized Controlled Trial
Authors: Desrosiers Alethea , Schafer Carolyn , Esliker Rebecca , Jambai Musu , Betancourt Theresa S 
Published: December 2020

Background
Past trauma and exposure to violence have been related to poor emotion regulation and household violence, which can have persistent mental health effects across generations. The Family Strengthening Intervention for Early Childhood Development (FSI-ECD/called Sugira Muryango in Rwanda) is an evidence-based behavioral home-visiting intervention to promote caregiver mental health, positive parenting practices, and early childhood development among families facing adversity. In Sierra Leone and other lower- and middle-income countries, mobile health (mHealth) technology has the potential to improve health care delivery and health outcomes.

Objective
This study aims to (1) apply a user-centered design to develop and test mHealth tools to improve supervision and fidelity monitoring of community health workers (CHWs) delivering the FSI-ECD and (2) conduct a pilot randomized controlled trial of the FSI-ECD to assess feasibility, acceptability, and preliminary effects on caregiver mental health, emotion regulation, caregiving behaviors, and family violence in high-risk families with children aged 6-36 months in comparison with control families receiving standard care.

Methods
We will recruit and enroll CHWs, supervisors, and families with a child aged 6-36 months from community health clinics in Sierra Leone. CHWs and supervisors will participate in 1 problem analysis focus group and 2 user interface/user experience cycles to provide feedback on mHealth tool prototypes. Families will be randomized to mHealth-supported FSI-ECD or standard maternal and child health services. We will collect quantitative data on caregiver mental health, emotion regulation, caregiving behaviors, and family functioning at baseline, postintervention, and 3-month follow up. We will use a mixed methods approach to explore feasibility and acceptability of mHealth tools and the FSI-ECD. Mixed effects linear modeling will assess FSI-ECD effects on caregiver outcomes. Cost-effectiveness analysis will estimate costs across FSI-ECD versus standard care.

Results
Funding for this study was received from the National Institutes of Mental Health on August 17, 2020. Institutional Review Board approval was received on September 4, 2020. Data collection is projected to begin on December 15, 2020.

Conclusions
This study will provide important data on the feasibility, acceptability, and preliminary efficacy of mHealth-supported delivery of an evidence-based family home-visiting intervention in a postconflict LMIC.

Trial Registration
ClinicalTrials.gov NCT04481399; https://clinicaltrials.gov/ct2/show/NCT04481399.

International Registered Report Identifier (IRRID)
PRR1-10.2196/25443
Efektivitas Supervisi Akademik Pengawas PAI dalam Membina Guru Agama SMP dan SMA di Kecamatan Ipuh Kabupaten Mukomuko
Authors: Hendri Nasrul 
Published: December 2020

This study aims to determine the effectiveness of Islamic education supervisors in fostering junior high school and senior high school religion subject teachers, including academic supervision on (1) planning, (2) implementation, (3) follow-up, (4) blocking and inhibiting factors. This research used an evaluative research approach. Respondents in this study amounted to 9 people, consisting of 2 supervisors and 7 Islamic teachers. Participants in this study consist of 1 Islamic education supervisor for junior high school, 1 Islamic education supervisor for senior high school, 5 Islamic education teachers in junior high school, and 2 Islamic education teachers in senior high school. Data were collected using the method of observation, interviews and documentation. The results of data analysis showed that the level of effectiveness of Islamic education supervisors in fostering Islamic educators in junior and senior high school has a score of 67.46%. It means less effective because supervisors do not master academic supervision techniques, rarely receive supervisory training, and take a long trip to teach between schools.
Editorial
Authors: Cocker Alan 
Published: December 2020

It is a pleasure to be able to introduce the first issue of BackStory. The idea behind this journal is to provide a medium for those interested in ‘looking back’ at New Zealand’s art, media and design history. These are the stories that lie behind current media, art and design production and practice in this country. It is envisaged that this new journal will provide an opportunity to explore our rich heritage in these fields.
In part the motivation to launch a new journal is to meet a perceived need. The country presently does not have a journal which has the focus envisaged for BackStory. The Journal of New Zealand Art History (JoNZAH) was last published in 2012/13 and its absence has meant that those interested in reading and writing about this aspect of our cultural history lost a valued publication. The editorial team has approached the Hocken Library who provided editorial and production input for the JoNZAH and gained their support for the BackStory initiative. It is acknowledged that the new journal is not a re-launch or continuation of the JoNZAH. Instead, BackStory: Journal of New Zealand Art, Media and Design History, seeks to broaden the scope of its predecessor to include media and design history. The editorial teamhope that those who valued the JoNZAH will find value in this journal as a worthy successor.The initial editorial team for BackStory is drawn from the Auckland University of Technology (AUT) and an Editorial Advisory Board has been established. The establishing editorial team are Minna Pesonen (Designer), Rosemary Brewer, Alan Cocker and Peter Hoar from the School of Communication Studies, Peter Gilderdale from the School of Art & Design and Simon Mowatt from the Faculty of Business. It is the hope of this team that BackStory has an appeal beyond academia and will inspire contributions from those working in this country’s libraries, galleries and museums as well as others who have an interest in the history of New Zealand art, design, photography and media. We are pleased that this first issue contains contributions from curators at the Auckland Museum and Te Papa, and that there is a wide representation of different material drawn from across the target disciplines. Our hope is that the quality of the research and writing, and the common New Zealand focus will entice readers into crossdisciplinary explorations.
All submissions except commentaries will be blind peer reviewed by two reviewers to conform to university research publication standards but we are seeking contributions that will have an appealbeyond the university. In the so-called online age the decision to publish a printed form is deliberate. The editorial team are seeking the highest print production standards conscious of the artifact value of this journal.
La ciencia del psicoanálisis y el psicoanálisis de la ciencia
Authors: Cazau Pablo 
Published: December 2020

Dentro del amplio espectro de temas que podrían relacionar el psicoanálisis con el conocimiento científico, en este artículo se rescatan dos cuestiones fundamentales: 1) las condiciones bajo las cuales el psicoanálisis puede ser considerado como ciencia, y 2) las explicaciones psicoanalíticas acerca del conocimiento científico y, en particular, las ofrecidas por el mismo Sigmund Freud y más tarde, por Gastón Bachelard, que indagarán las raíces del discurso científico en la psicodinámica del inconciente.
El psicoanálisis “como ciencia” y el psicoanálisis “de la ciencia” son así dos enfoques alternativos y en cierto sentido complementarios donde ambos sistemas de creencias se escrutan mutuamente: la ciencia mirando al psicoanálisis, y el psicoanálisis mirando a la ciencia. Se concluye que en el fondo no se trata de enfoques contrapuestos sino más bien de dos planteos orientados hacia el mismo objetivo que es la construcción de una epistemología del psicoanálisis.
Alkalinity of Irrigation Return Water Influences Nutrient Removal Efficacy of Floating Treatment Wetland Systems1
Authors: Garcia Chance Lauren M. , Albano Joseph P. , Lee Cindy M. , Rovder Ashley M. , White Sarah A. 
Published: December 2020

Abstract
Water quality concerns often prevent reuse of captured irrigation return water for irrigation of specialty crops. Prior research indicated alkalinity of specialty crop operation irrigation varies from 0 to &gt;500 mg.L−1 ( &gt;0.06 oz.gal−1) CaCO3 across the United States. Floating treatment wetlands (FTWs) are an option for remediation of nutrients in irrigation return water, but effects of variable alkalinity on nutrient removal efficiency of FTWs are unknown. An experimental FTW system was developed to quantify the effect of alkalinity on the growth and nutrient uptake capacity of three plant species. ‘Rising Sun' Japanese iris (Iris ensata ‘Rising Sun’ Thunb.), upright sedge (Carex stricta Lam.);, and switchgrass (Panicum virgatum L.). were grown for 6 weeks at one of five alkalinity treatment levels, representing the alkalinity range of nursery and greenhouse irrigation runoff: 0, 100, 200, 300, and 400 mg.L−1 CaCO3 (0, 0.01, 0.02, 0.04, 0.05 oz.gal−1 CaCO3). Overall, Japanese iris demonstrated consistent remediation across each alkalinity treatment for both nutrient load reduction and plant accumulation. Species of iris warrant greater consideration and use in bioremediation systems. Both upright sedge and switchgrass could be used in systems with appropriate alkalinity levels. Future work should consider assessing novel plants at different points within their growth cycle, extended exposure durations, and decreased hydraulic retention time.
Index words: Aquatic plant, nitrogen, phosphorus, sodium bicarbonate, nitrogen speciation.
Species Used in this study: ‘Rising Sun' Japanese iris (Iris ensata ‘Rising Sun' Thunb.); upright sedge (tussock sedge) (Carex stricta Lam.); switchgrass (Panicum virgatum L.).
Adiciones a la flora briofítica del Espacio Natural Sierra de las Nieves (Málaga, España)
Authors: Guerra Juan , Casimiro-Soriguer Solanas Federico , Cabezudo Artero Baltasar 
Published: December 2020

Se citan 14 especies de briofitos nuevas para el Espacio Natural Sierra de las Nieves, elevándose a 257 el total de especies localizadas en el territorio. Destacamos la presencia de dos especies de Schistidium recientemente descritas y de Neckera cephalonica Jur. & Unger y Eurhynchiastrum pulchellum (Hedw.) Ignatov & Huttunen, taxones muy raros en el sur de la Península Ibérica.
Pojęcie bezpieczeństwa sanitarno-epidemiologicznego i jego konteksty prawne
Authors: Czechowicz Sebastian 
Published: December 2020

Niniejsze opracowanie podejmuje problematykę bezpieczeństwa sanitarno-epidemiologicznego jako terminu dogmatycznego. Pojęcie bezpieczeństwa sanitarno-epidemiologicznego nie jest powszechnie funkcjonującym sformułowaniem. W doktrynie poruszane jest przy okazji omawiania zagadnień bezpieczeństwa państwa bądź też bezpieczeństwa zdrowotnego. Wskazuje się na pewne cechy tej kategorii bezpieczeństwa w systematyce bezpieczeństwa wewnętrznego państwa.Niezwykle istotne z punktu widzenia działalności organów administracji publicznej jest wyodrębnienie tej kategorii w ramach bezpieczeństwa powszechnego. Organ wyspecjalizowany, taki jak Państwowa Inspekcja Sanitarna, działa w ściśle określonych sytuacjach zagrożenia bezpieczeństwa sanitarnego i w obszarze polityki przeciwepidemicznej. Wskazywanie na funkcjonowanie tego typu organu w ramach bezpieczeństwa powszechnego jest zbyt daleko idącym uogólnieniem, zasadne zatem będzie dokonanie próby wyodrębnienia pojęcia bezpieczeństwa sanitarno-epidemiologicznego z przyjętej systematyki bezpieczeństwa wewnętrznego państwa. Rozważania będą miały charakter dogmatyczno-prawny i popartezostaną bogatą literaturą przedmiotu i przykładami legislacyjnymi.
Role of HRCT Temporal Bone in Pre-operative Assessment of Tegmen Height in Chronic Otitis Media Patients
Authors: Husain Mushahid , Khanduri Sachin , Faiz Syed M. , Abbas Syed Zain , Yadav Poonam , Khan Ahmad Umar , Singh Anchal , Khan Mazhar 
Published: December 2020

Objectives:
High-resolution CT (HRCT) temporal bone has emerged as a useful option in pre-operative assessment of tegmen height in chronic otitis media patients.

Material and Methods:
A total of 60 patients with clinical suspicion of chronic otitis media were enrolled in the study. HRCT evaluation was done using Siemens Somatom Force 384 slice multidetector computed tomography machine. We radiologically assess tegmen height using lateral semicircular canal as a reference point on HRCT. Final result has been based on correlation of radiological and intraoperative findings. Diagnostic efficacy of HRCT temporal bone was evaluated in terms of sensitivity, specificity, PPV, NPV, and accuracy for pre-operative assessment of tegmen height.

Results:
The correlation between actual tegmen height and estimated tegmen height (by equation) was 0.457 which is highly significant (P < 0.001). In the study, the mean tegmen height of exposed dura (ED) was 5.81 ± 1.71 (95% CI 4.91–6.70) while the mean tegmen height of non-exposed dura (NED) was 8.40 ± 1.31 (95% CI 8.02– 8.78). Highly significant difference was found in mean tegmen height between ED and NED cases (P < 0.001).

Conclusion:
Pre-operative CT assessment of tegmen height is an important parameter in assessing risk of dural injury during tympanomastoid surgeries.
Pengaruh Faktor Kepribadian dalam Penerapan Teknologi Informasi pada Unit Vertikal Direktorat Jenderal Perbendaharaan Di Pontianak dengan Menggunakan Technology Acceptance Model (TAM)
Authors: B2041142010 Irfan Sudarmaji 
Published: December 2020

Penelitian ini bertujuan untuk menguji dan menganalisa pengaruh faktor kepribadian dalam penerapan teknologi informasi dengan menggunakan metode Technology Acceptance Model (TAM). Faktor kepribadian diukur dengan menggunakan variabel Big Five Personality yang terdiri dari Extraversion (X1), Agreeableness (X2), Conscientiousness (X3), Neuroticism (X4), dan Openness to Experience (X5) sedangkan metode TAM diukur dari 3 kontruk yaitu Perceived Usefulness (Y1), Perceived Ease of Use (Y2), dan Behavioral Intention to Use (Z). Objek penelitian yaitu 80 responden yang merupakan seluruh pegawai Direktorat Jenderal Perbendaharaan di Pontianak (Kanwil DJPb Kalbar dan KPPN Pontianak). Jenis penelitian yang ditetapkan dalam penelitian adalah dengan metode survei analitik bersifat penelitian penjelasan (explanatory study), dengan pendekatan kuantitatif, deskriptif korelasi dan desain cross-sectional. Alat analisis menggunakan metode SEM (structural equation modeling) Warp PLS versi 6.0. Hasil penelitian menunjukkan bahwa seluruh faktor Big Five Personality mempunyai pengaruh positif dan signifikan terhadap dua konstruk TAM yaitu Perceived Usefulness, Perceived Ease of Use. Sedangkan terhadap variabel Behavioral Intention to Use, faktor Big Five Personality: Extraversion, Neuroticism, dan Openness to Experience mempunyai pengaruh positif dan signifikan. Untuk variabel Agreeableness dan Conscientiousness menunjukkan hasil yang tidak signifikan.Kata kunci: Teknologi Informasi, Big Five Personality, Technology Acceptance Model
STUDI PEMANFAATAN TUMBUHAN OBAT SEBAGAI TONIK OLEH PENGOBAT TRADISIONAL DI DESA KARYA BAKTI KECAMATAN SUNGAI BETUNG KABUPATEN BENGKAYANG
Authors: Riconadi Riconadi , Arbiastutie Yanieta , Mariani Yeni , Sisillia Lolyta , Yusro Fathul 
Published: December 2020

There is a long history of the plant's usage as medicine to overcome various diseases and maintain people's health conditions in communities. Among its multiple benefits, medicinal plants are also used to strengthen the body organs (tonic). The use of medicinal plants as tonics is still carried out by the society of Karya Bakti Village, Sungai Betung District, Bengkayang Regency, especially by traditional healers (dukun) who are trusted by the community to help treat various diseases. This study aims to analyze plant's use by traditional healers in Karya Bakti Village, Bengkayang Regency. The data was collected by interviewing two traditional healers who were selected based on the snowball sampling technique. The interview results revealed that the village's traditional healer used 32 species of medicinal plants belonging to 25 families. The most widely used plant family is Zingiberaceae (19%), with the highest habitus is herbs (31.25%). The most commonly used part is the root (28.13%), the form of single ingredients (53%) by boiling processing (74.36%), the administration is orally (77.5%) with a frequency of use three times a day (75%). The study results proved that traditional healers in Karya Bakti Village were still using medicinal plants as tonics.Keywords: medicinal plants, tonic, traditional healers