bluuebunny/crossref_metadata_2025_split huggingface dataset:
Winning Hearts and Minds with Economic Sanctions? Evidence from a Survey Experiment in Venezuela
Authors: Sejersen Mikkel 
Published: April 2020

Abstract
Previous research contends that economic sanctions must benefit opposition groups relative to the incumbent regime in order to generate policy change. However, studies have found that sanctions often backfire and increase regime support. While this rally-around-the-flag effect is well known, it is currently unclear how senders can prevent it. In this article, I use individual-level data from a targeted state to examine whether a sender's framing of the sanctions may play a role in preventing the rally-around-the-flag effect. A survey experiment conducted among respondents in Venezuela demonstrates that the public attitude toward sanctions is shaped by the framing of the sanctions. Specifically, people adopt more favorable views when interpreting sanctions as targeted measures against regime members with the explicit goal of protecting fundamental human rights. The effects are evident among moderates, which is significant as they are otherwise the group most likely to rally behind the regime.
Fluid pressure diffusion effects on the excess compliance matrix of porous rocks containing aligned fractures
Authors: Castromán Gabriel A , Barbosa Nicolás D , Rubino J Germán , Zyserman Fabio I , Holliger Klaus 
Published: April 2020

SUMMARYThe presence of sets of open fractures is common in most reservoirs, and they exert important controls on the reservoir permeability as fractures act as preferential pathways for fluid flow. Therefore, the correct characterization of fracture sets in fluid-saturated rocks is of great practical importance. In this context, the inversion of fracture characteristics from seismic data is promising since their signatures are sensitive to a wide range of pertinent fracture parameters, such as density, orientation and fluid infill. The most commonly used inversion schemes are based on the classical linear slip theory (LST), in which the effects of the fractures are represented by a real-valued diagonal excess compliance matrix. To account for the effects of wave-induced fluid pressure diffusion (FPD) between fractures and their embedding background, several authors have shown that this matrix should be complex-valued and frequency-dependent. However, these approaches neglect the effects of FPD on the coupling between orthogonal deformations of the rock. With this motivation, we considered a fracture model based on a sequence of alternating poroelastic layers of finite thickness representing the background and the fractures, and derived analytical expressions for the corresponding excess compliance matrix. We evaluated this matrix for a wide range of background parameters to quantify the magnitude of its coefficients not accounted for by the classical LST and to determine how they are affected by FPD. We estimated the relative errors in the computation of anisotropic seismic velocity and attenuation associated with the LST approach. Our analysis showed that, in some cases, considering the simplified excess compliance matrix may lead to an incorrect representation of the anisotropic response of the probed fractured rock.
Data-driven and machine learning identification of seismic reference stations in Europe
Authors: Pilz Marco , Cotton Fabrice , Kotha Sreeram Reddy 
Published: April 2020

SUMMARYThe growing seismic networks and the increasing number of permanent seismic stations can help in improving the physical basis of seismic hazard assessment. For this purpose, the definition of reference site conditions is of great significance. If a reliable estimate of the reference ground motion is known, its modification at any given site can be modelled with respect to that reference site. Since the choice of a well-characterized reference site is not straightforward, mainly due to the high variability in the shallow layers, such choices prove to be affected by large uncertainties. While proxy parameters like the average S-wave velocity over the uppermost 30 m (vS30) might help in characterizing reference site conditions, such parameters are neither available at all sites nor do they allow concluding that the site is not affected by amplification and attenuation effects. In this study, we identify prospective reference sites across Europe in a harmonized and fully data-driven way. All analysis is based on freely available geological and geophysical data and no on-site measurements or site-specific proxies are required. The study accounts for both the influence of amplification and attenuation in a large frequency range. To address the key conceptual issues, we verify our classification based on machine learning techniques in which the influence of the individual site characterization parameters is investigated. Our study indicates that around 250 sites in Europe over more than 2000 investigated are not affected by local site effects and can de facto be considered as reference sites based on the criteria applied.
Relationship between birth weight and chronic kidney disease: evidence from systematics review and two-sample Mendelian randomization analysis
Authors: Yu Xinghao , Yuan Zhongshang , Lu Haojie , Gao Yixin , Chen Haimiao , Shao Zhonghe , Yang Jiaji , Guan Fengjun , Huang Shuiping , Zeng Ping 
Published: April 2020

Abstract
Observational studies showed an inverse association between birth weight and chronic kidney disease (CKD) in adulthood existed. However, whether such an association is causal remains fully elusive. Moreover, none of prior studies distinguished the direct fetal effect from the indirect maternal effect. Herein, we aimed to investigate the causal relationship between birth weight and CKD and to understand the relative fetal and maternal contributions. Meta-analysis (n = ~22 million) showed that low birth weight led to ~83% (95% confidence interval [CI] 37–146%) higher risk of CKD in late life. With summary statistics from large scale GWASs (n = ~300 000 for birth weight and ~481 000 for CKD), linkage disequilibrium score regression demonstrated birth weight had a negative maternal, but not fetal, genetic correlation with CKD and several other kidney-function related phenotypes. Furthermore, with multiple instruments of birth weight, Mendelian randomization showed there existed a negative fetal casual association (OR = 1.10, 95% CI 1.01–1.16) between birth weight and CKD; a negative but non-significant maternal casual association (OR = 1.09, 95% CI 0.98–1.21) was also identified. Those associations were robust against various sensitivity analyses. However, no maternal/fetal casual effects of birth weight were significant for other kidney-function related phenotypes. Overall, our study confirmed the inverse association between birth weight and CKD observed in prior studies, and further revealed the shared maternal genetic foundation between low birth weight and CKD, and the direct fetal and indirect maternal causal effects of birth weight may commonly drive this negative relationship.
Adaption potential of Crassostrea gigas to ocean acidification and disease caused by Vibrio harveyi
Authors: Nordio Davide , Khtikian Natalie , Andrews Sean , Bertotto Daniela , Leask Karen , Green Timothy 
Published: April 2020

Abstract
The survival and development of bivalve larvae is adversely impacted by ocean acidification and Vibrio infection, indicating that bivalves need to simultaneously adapt to both stressors associated with anthropogenic climate change. In this study, we use a half-dial breeding design to estimate heritability (h2) for survival to Vibrio harveyi infection and larval shell length to aragonite undersaturated and normal conditions in laboratory-reared Crassostrea gigas. Phenotypic differences were observed between families for these traits with heritability estimated to be moderate for survival to V. harveyi challenge (h2 = 0.25) and low for shell length in corrosive (Ωaragonite = 0.9, h2 = 0.15) and normal conditions (Ωaragonite = 1.6, h2 = 0.15). Predicted breeding values for larval shell length are correlated between aragonite-undersaturated and normal conditions (Spearman r = 0.63, p &lt; 0.05), indicating that larger larvae tend to do better in corrosive seawater. Aquaculture hatcheries routinely cull slow-growing larvae to reduce and synchronize time taken for larvae to metamorphose to spat, thus inadvertently applying size-related selection for larger larvae. This indirect selection in the hatchery populations provides a plausible explanation why domesticated oyster populations are less sensitive to ocean acidification.
When past is not a prologue: Adapting informatics practice during a pandemic
Authors: Kannampallil Thomas G , Foraker Randi E , Lai Albert M , Woeltje Keith F , Payne Philip R O 
Published: April 2020

Abstract
Data and information technology are key to every aspect of our response to the current coronavirus disease 2019 (COVID-19) pandemic—including the diagnosis of patients and delivery of care, the development of predictive models of disease spread, and the management of personnel and equipment. The increasing engagement of informaticians at the forefront of these efforts has been a fundamental shift, from an academic to an operational role. However, the past history of informatics as a scientific domain and an area of applied practice provides little guidance or prologue for the incredible challenges that we are now tasked with performing. Building on our recent experiences, we present 4 critical lessons learned that have helped shape our scalable, data-driven response to COVID-19. We describe each of these lessons within the context of specific solutions and strategies we applied in addressing the challenges that we faced.
Excessively activated plasminogen in human plasma cleaves VWF multimers and reduces collagen-binding activity
Authors: Togashi Kenshi , Suzuki Satoshi , Morita Sae , Ogasawara Yuki , Imamura Yasutada , Shin Yongchol 
Published: April 2020

AbstractPlasmin (Pm) is a serine protease that can dissolve fibrin clots. Several possible functions of Pm in blood other than fibrinolysis have been proposed. To explore the effects of Pm on primary haemostasis, we evaluated the cleavage of von Willebrand factor multimers (VWFMs) in human plasma by streptokinase (SK)-activated plasminogen (Pg) and the binding ability of the digested VWFMs to collagen. SK-activated Pg and ADAMTS13 (a VWF-cleaving enzyme) in human plasma cleaved VWFMs in conformation-dependent manners through dialysis to the urea-containing buffer. However, VWFMs in human plasma under vortex-based shear stress were cleaved by SK-activated Pg but not by ADAMTS13. These results suggested that the VWFM-cleavage sites in human plasma are exposed to some extent by vortex-based shear stress for Pm but not for ADAMTS13. Additionally, we revealed that cleavage by SK-activated Pg reduced VWFMs’ binding ability to collagen, and VWFMs in human plasma were cleaved by Pm at several sites. These results suggest that SK-activated Pg degrades VWFMs, reduces their binding abilities to collagen and affects primary haemostasis. Because excessive Pg activation can degrade fibrinogen/fibrin, we propose that SK-activated Pg in blood may cause impaired primary and secondary haemostasis.
Genetic Diversity and Connectivity of Southern Right Whales (Eubalaena australis) Found in the Brazil and Chile–Peru Wintering Grounds and the South Georgia (Islas Georgias del Sur) Feeding Ground
Authors: Carroll Emma L , Ott Paulo H , McMillan Louise F , Galletti Vernazzani Bárbara , Neveceralova Petra , Vermeulen Els , Gaggiotti Oscar E , Andriolo Artur , Baker C Scott , Bamford Connor , Best Peter , Cabrera Elsa , Calderan Susannah , Chirife Andrea , Fewster Rachel M , Flores Paulo A C , Frasier Timothy , Freitas Thales R O , Groch Karina , Hulva Pavel , Kennedy Amy , Leaper Russell , Leslie Matthew S , Moore Michael , Oliveira Larissa , Seger Jon , Stepien Emilie N , Valenzuela Luciano O , Zerbini Alexandre , Jackson Jennifer A 
Published: April 2020

AbstractAs species recover from exploitation, continued assessments of connectivity and population structure are warranted to provide information for conservation and management. This is particularly true in species with high dispersal capacity, such as migratory whales, where patterns of connectivity could change rapidly. Here we build on a previous long-term, large-scale collaboration on southern right whales (Eubalaena australis) to combine new (nnew) and published (npub) mitochondrial (mtDNA) and microsatellite genetic data from all major wintering grounds and, uniquely, the South Georgia (Islas Georgias del Sur: SG) feeding grounds. Specifically, we include data from Argentina (npub mtDNA/microsatellite = 208/46), Brazil (nnew mtDNA/microsatellite = 50/50), South Africa (nnew mtDNA/microsatellite = 66/77, npub mtDNA/microsatellite = 350/47), Chile–Peru (nnew mtDNA/microsatellite = 1/1), the Indo-Pacific (npub mtDNA/microsatellite = 769/126), and SG (npub mtDNA/microsatellite = 8/0, nnew mtDNA/microsatellite = 3/11) to investigate the position of previously unstudied habitats in the migratory network: Brazil, SG, and Chile–Peru. These new genetic data show connectivity between Brazil and Argentina, exemplified by weak genetic differentiation and the movement of 1 genetically identified individual between the South American grounds. The single sample from Chile–Peru had an mtDNA haplotype previously only observed in the Indo-Pacific and had a nuclear genotype that appeared admixed between the Indo-Pacific and South Atlantic, based on genetic clustering and assignment algorithms. The SG samples were clearly South Atlantic and were more similar to the South American than the South African wintering grounds. This study highlights how international collaborations are critical to provide context for emerging or recovering regions, like the SG feeding ground, as well as those that remain critically endangered, such as Chile–Peru.
A new method to estimate hair density of small mammal pelage
Authors: Cui Liang Yu , Liu Wei , Xu Yan Chun , Yang Shu Hui , Dahmer Thomas D 
Published: April 2020

AbstractHair density is the most important structural parameter contributing to insulation performance of mammalian pelage, and often is measured in ecophysiological, thermal biological, and evolutionary studies. To date, hair density has been measured using invasive methods on research objects; however, such methods remain challenging despite efforts to increase their ease of use. In this paper, we develop a new method to estimate hair density without skin sampling. We expressed hair density as the inverse of the number of hairs per unit area, that is, the surface area occupied by a single hair (Ah). This area could be further estimated by measuring distances between nearest neighboring hairs (Ln) and calculating the areas of triangles (A) defined by three randomly selected nearest neighboring hairs and representing half of Ah. Empirical tests using 11 skin samples from specimens of six small mammal species showed this to be a simple, lightly invasive, but accurate and widely applicable method.
Determining sex of adult Pacific walruses from mandible measurements
Authors: Taylor Nathan , Clark Casey T , Misarti Nicole , Horstmann Lara 
Published: April 2020

AbstractPacific walruses (Odobenus rosmarus divergens) play a vital role in Arctic marine ecosystems and the subsistence lifestyle of Alaska Native communities. Museum collections contain numerous archaeological and historic walrus specimens that have proven useful in a variety of studies; however, for many cases, the sex of these specimens is unknown. Sexes of adult (&gt; 5 years determined by tooth aging) Atlantic walruses (Odobenus rosmarus rosmarus) have been accurately determined in previous studies using mandible measurements. We tested the validity of this approach for Pacific walruses, and used full fusion of the mandibular symphysis to define adults. Using high precision digital calipers (± 0.01 mm), four measurements were taken either on the left or right side of 91 walrus mandibles: 80 modern mandibles (70 known-sex specimens; 10 unknown-sex specimens) and 11 archaeological mandibles of unknown sex. We used linear discriminant function analysis (LDFA) to determine what measurements best distinguished Pacific walrus males from females. Minimum mandible thickness had the most predictive power, whereas mandible length, height, and depth, were less predictive. Posterior probabilities indicated that LDFA classified the known-sex Pacific walruses with 100% accuracy, and unknown sex with ≥ 90% probability. The ability to define the sex of unknown individuals accurately could greatly increase the sample size of future projects dealing with skeletal remains, and will improve future research efforts.
Dominance hierarchy on palm resource partitioning among Neotropical frugivorous mammals
Authors: Akkawi Paula , Villar Nacho , Mendes Calebe P , Galetti Mauro 
Published: April 2020

AbstractIn tropical forests, the diets of many frugivorous mammals overlap, yet how hyper-diverse assemblages of consumers exploit resources and coexist remains poorly understood. We evaluated competitive interactions among three species of terrestrial frugivorous mammals, the ungulate Tayassu pecari (white-lipped peccary), its close relative Pecari tajacu (collared peccary), and a large rodent (Dasyprocta azarae, agouti), in their exploitation strategies of palm resources of different quality. We conducted the study in a large isolated fragment at the tropical Atlantic Forest of Brazil, where these mammal species show high spatial and temporal overlap. We evaluated if body mass and foraging group size define a hierarchy in exploitation of preferentially richer palm resources. We used camera traps and two-species occupancy models to examine patterns of co-occurrence and variable interaction strength between these consumers and three species of palms. Our analyses supported the hypothesis of partial resource overlap but no competition among frugivores, and a body mass dominance hierarchical exploitation of resources. The larger frugivore (white-lipped peccary) dominated patches of the lipid-rich palm Euterpe edulis, where the smallest frugivore (agouti) was absent. Instead, the smallest frugivore concentrated its foraging in areas with the poorest palm resource, Syagrus oleracea. Collared peccaries preferred areas of high abundance of Syagrus romanzoffiana when the other two mammal species were rarely detected or absent, strongly avoided patches of E. edulis, and showed higher average detection probabilities when agoutis were present. Our study highlights the important role of behavioral plasticity in promoting coexistence and indicates that through context-dependent interactions and hierarchical partitioning of resources, consumers can avoid strong competition, even under conditions of high spatial and temporal overlap and high levels of habitat fragmentation and isolation.
Understanding the Meaning of Concepts Across Domains Through Collocation Analysis: An Application to the Study of Red Tape
Authors: Kaufmann Wesley , Haans Richard F J 
Published: April 2020

AbstractPublic administration scholarship is facing a crisis of legitimacy, as academic research is viewed as both increasingly irrelevant for practice and methodologically underdeveloped. In this study, we put forward a so-called collocation analysis approach, which is a useful tool for studying the meaning of key concepts in public administration and (re)focusing academic research agendas to salient societal problems by identifying how concepts are talked about in different domains. To illustrate our approach, we assess the meaning of red tape in academia, policy-making, and the media. Our dataset consists of 255 academic articles, 2,179 US Congressional Records, and 37,207 US newspaper articles mentioning red tape. We find that red tape has specific connotations in each domain, which limits the extent to which these domains are being bridged. Using the insights from our analysis, we develop a red tape research agenda that aims for more relevant and rigorous knowledge generation and conclude by setting out implications and ways forward for public administration research at large.
Linking signaling pathways to histone acetylation dynamics in plants
Authors: Jiang Jianjun , Ding Adeline B , Liu Fengquan , Zhong Xuehua 
Published: April 2020

AbstractAs sessile organisms, plants face versatile environmental challenges and require proper responses at multiple levels for survival. Epigenetic modification of DNA and histones is a conserved gene-regulatory mechanism and plays critical roles in diverse aspects of biological processes, ranging from genome defense and imprinting to development and physiology. In recent years, emerging studies have revealed the interplay between signaling transduction pathways, epigenetic modifications, and chromatin cascades. Specifically, histone acetylation and deacetylation dictate plant responses to environmental cues by modulating chromatin dynamics to regulate downstream gene expression as signaling outputs. In this review, we summarize current understandings of the link between plant signaling pathways and epigenetic modifications with a focus on histone acetylation and deacetylation.
Suberized transport barriers in plant roots: the effect of silicon
Authors: Kreszies Tino , Kreszies Victoria , Ly Falko , Thangamani Priya Dharshini , Shellakkutti Nandhini , Schreiber Lukas 
Published: April 2020

Abstract
Plant roots are the major organs that take up water and dissolved nutrients. It has been widely shown that apoplastic barriers such as Casparian bands and suberin lamellae in the endo- and exodermis of roots have an important effect on regulating radial water and nutrient transport. Furthermore, it has been described that silicon can promote plant growth and survival under different conditions. However, the potential effects of silicon on the formation and structure of apoplastic barriers are controversial. A delayed as well as an enhanced suberization of root apoplastic barriers with silicon has been described in the literature. Here we review the effects of silicon on the formation of suberized apoplastic barriers in roots, and present results of the effect of silicon treatment on the formation of endodermal suberized barriers on barley seminal roots under control conditions and when exposed to osmotic stress. Chemical analysis confirmed that osmotic stress enhanced barley root suberization. While a supplementation with silicon in both, control conditions and osmotic stress, did not enhanced barley root suberization. These results suggest that enhanced stress tolerance of plants after silicon treatment is due to other responses.
Study of recent outburst in the Be/X-ray binary RX J0209.6−7427 with AstroSat: a new ultraluminous X-ray pulsar in the Magellanic Bridge?
Authors: Chandra Amar Deo , Roy Jayashree , Agrawal P C , Choudhury Manojendu 
Published: April 2020

ABSTRACT
We present the timing and spectral studies of RX J0209.6–7427 during its rare 2019 outburst using observations with the Soft X-ray Telescope (SXT) and Large Area X-ray Proportional Counter (LAXPC) instruments on the AstroSat satellite. Pulsations having a periodicity of 9.29 s were detected for the first time by the NICER mission in the 0.2–10 keV energy band and, as reported here, by AstroSat over a broad energy band covering 0.3–80 keV. The pulsar exhibits a rapid spin-up during the outburst. Energy resolved folded pulse profiles are generated in several energy bands in 3–80 keV. To the best of our knowledge this is the first report of the timing and spectral characteristics of this Be binary pulsar in hard X-rays. There is suggestion of evolution of the pulse profile with energy. The energy spectrum of the pulsar is determined and from the best-fitting spectral values, the X-ray luminosity of RX J0209.6−7427 is inferred to be 1.6 × 1039 erg s−1. Our timing and spectral studies suggest that this source has features of an ultraluminous X-ray pulsar in the Magellanic Bridge. Details of the results are presented and discussed in terms of the current ideas.