bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immunopathogenetic significance of activation and apoptosis of immunocompetent cells in children with HIV infection
Authors: Denisenko V. B. , Simovanyan E. M. 
Published: October 2020

The purposeis to clarify the immunopathogenetic significance of immunocompetent cells activation and apoptosis in children with HIV-infection.Materials and methods. A clinical and immunological examination of 92 children aged 1 to 5 years old with HIVinfection in latent stage 3 (25), in the stage of secondary diseases 4A (21), 4B (22) and 4V (24) was conducted.Results.During the clinical examination, the consistent appearance of HIV-associated symptoms, opportunistic infections, and tumors was noted. Changes in the immune status included abnormalities in the T-cell component – a decrease in the number of CD4-, CD3-, increase of CD8-lymphocytes, inversion of the CD4/CD8 ratio, in the B-cell component – hyperimmunoglobulinemia, increase in the content of circulating immune complexes, in the part of innate immunity factors – a decrease in the intensity of the oxygen-dependent neutrophil metabolism and its reserve capabilities. Identified impaired positive activation of lymphocytes – a decrease in the number of CD25- and an increase in HLADR-cells. An increase in the expression of CD95-receptors on the lymphocyte membrane, an increase in the number of lymphocytes in the early (AnV) and late stages of apoptosis (AnV/Pr) was found. With the progression of HIV infection, there was a deepening of these shifts in immunological parameters, especially during the transition to the stage of secondary diseases 4V (AIDS).Conclusion.An immunological examination and correlation analysis showed that an important immunopathogenetic mechanism for reducing the number of CD4 lymphocytes in children with HIV infection is the activation of apoptosis involving the receptor and mitochondrial mechanisms. One of the reasons for the formation of depressed cellular immunity was the hyperactivation of immunocompetent cells. The findings provide a rationale for the timely prescription of antiretroviral therapy for children with HIV-infection, which will prevent hyperactivation and apoptosis of immune system cells.
Pathogenetic variants of ventriculitis in children
Authors: Pozhivil A. S. , Shcherbuk A. Yu. , Lyapin A. P. , Shcherbuk Yu. A. 
Published: October 2020

The aim of the study: to analyze the pathogenetic structure of ventriculitis, their relationship with age, risk factors, study the etiological characteristics, clinical and diagnostic features, evaluate outcomes of ventriculitis and features of mortality.Materials and methods: a retrospective analysis of inpatient medical charts of 72 children with ventriculitis received treatment in the neurosurgery department of Filatov Children hospital №5, St-Petersburg, from January 2008 to December 2017 was carried out.Results: Most cases of ventriculitis occurred in infants (up to 1 year) and young children (1-3 years old). The largest group among pathogenetic variants of ventriculitis was shunt infection – 50 (69.44%) cases. Other groups were: ventriculostomy-associated ventriculitis – 12 (16,67%) cases; ventriculitis following a neurosurgical procedure without external ventricular drainage – 6 (8,33%) cases; ventriculitis complicated meningitis in patients without prior neurosurgery – 4 (5,56%) cases. The presence of such risk factors for ventriculitis as cerebrospinal fluid leakage (18,06%), intraventricular blood prior to the development of ventriculitis (22,22%), and other systemic infections (59,72%) were noted. The crucial role in the diagnosis of ventriculitis is played by the inflammatory changes in the ventricular cerebrospinal fluid on the background of specific clinical findings and indicative anamnesis. The commonest organism causing ventriculitis in the study was Staphylococcus epidermidis – 24 (33,33%) patients. Ventriculitis mortality rate was 8,33% (6 cases). Analysis of adverse outcomes revealed that aggressive health-care-associated multidrug resistant organisms are more dangerous for life, especially in patients with severe central nervous system pathology prior to ventriculitis.
Cytomegalovirus uveitis in HIV-infected patients: course and outcomes
Authors: Sizova T. D. , Khokkanen V. M. , Gusev D. A. , Boyko E. V. 
Published: October 2020

Cytomegalovirus uveitis is one of the AIDS marker diseases, develops with severe immunodeficiency and is the main cause of blindness in HIV-infected patients.The aim of our work is to study the course and outcomes of CMV uveitis in patients with HIV infection over the past 10 years.Materials and methods. The study was conducted at the St. Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases and at the Department of Ophthalmology of North-Western State Medical University named after I.I. Mechnikov. The analysis of statistical data of HIV Newsletters in St. Petersburg for 2009-2019 was carried out, as well as the Journal of Ophthalmologist Examination of the AIDS Center to assess the long-term dynamics of detection of CMV uveitis, CMV associated retinal detachment, and cases of vision loss.Results. On average, CMV eye damage occurred in 1.65% of patients. In most cases, the involvement of the retina was predominantly peripheral (50-89%). Neuritis, panuveitis, cystic macular edema and retinal detachment were also registered. A positive strong linear relationship was found between the number of new cases of HIV infection already detected in the AIDS stage and new cases of cytomegalovirus damage to the organ of vision. There is a very strong inverse linear relationship between the frequency of detection of CMV uveitis and the amount of antiretroviral therapy provided.Conclusion. Conducting antiretroviral therapy and providing it to an increasing number of patients helps to reduce the incidence of HIV infection in St. Petersburg and probably secondary CMV infection with damage to the organ of vision.
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE TEAM GAMES TOURNAMENT TERHADAP PEMAHAMAN KONSEP PESERTA DIDIK PADA PEMBELAJARAN FISIKA
Authors: Agustina Agustina Agustina , Misdalina Misdalina , Lefudin Lefudin 
Published: October 2020

The formulation of the problem in this study is the effect of the Cooperative Learning model of the types of Team Games Tournament on the ability of students to understand the concept of physics learning in class X in SMK PGRI 2 Palembang. This study aims to determine whether or not there is an influence of the cooperative learning model of type of Team Games Tournament (TGT) on the ability of students to understand the concepts of physics in class X learning at SMK PGRI 2 Palembang. The research method used is the Experimental Design method, the category of Posstest-Only Control Design. in this design often used in research experiments with data collection technigues obtained using tests, and documentation.The average value of student learning outcomes in the experimental class can be categorized as good at 78.47 by using the cooperative games tournament type (TGT) Model, while the average value of the learning outcomes of the control class by not using the model cooperative Team Type Tournament games can be categorized enough with the average student learning outcomes is 63.05. Based on calculations t arithmetic > t table = 7.105 > 1.667 ie t arithmetic = 7.105 and t table = 1.667 then accept the hypothesis (ha) which means ” There is an influence of the cooperative learning model Team Games Tournament type (TGT) on the ability of students to understand the concept of learning physics in class X in SMK PGRI 2 Palembang.
Rancangan Penempatan Modul Surya dan Simulasi PLTS Fotovoltaik Atap Gedung RSPTN Rumah Sakit Universitas Udayana
Authors: Merta Kadek Hari , Kumara I. N. S. , Ariastina W. G. 
Published: October 2020

Indonesia membutuhkan energi listrik yang tinggi tetapi bahan bakar fosil sudah semakin sedikit. Pemerintah mengatasi kondisi ini tersebut dengan kebijakan energi nasional yang bertujuan mengurangi penggunaan energi fosil dan meningkatkan peran Energi Baru dan Terbarukan. Salah satu sumber energi terbarukan adalah energi surya. Universitas Udayana memiliki potensi untuk mengembangkan PLTS di Rumah Sakit Perguruan Tinggi Negeri Universitas Udayana. Dalam paper ini, dilakukan pengkajian pengembangan PLTS pada RSPTN Universitas Udayana. Didapatkan bahwa RSPTN Universitas Udayana berpotensi menghasilkan daya listrik sebesar 835,560 Wp. PLTS pada atap Gedung #1 menghasilkan 142,560 Wp yang mampu mensuplai 31.32 % dari total daya jika Gedung #1 sudah beroperasi penuh. PLTS juga menghasilkan energi sebesar 166,407 kWh per tahun yang mampu mensuplai 22.6 % dari konsumsi energi listrik Gedung #1. PLTS pada atap Gedung #1 dan atap parkir menghasilkan 226,710 Wp yang mampu mensulpai 46.98 % dari total daya jika Gedung #1 sudah beroperasi penuh. PLTS juga menghasilkan energi sebesar 249,610 kWh per tahun yang mampu mensuplai 32.8 % dari konsumsi energi listrik Gedung.
Kata Kunci— energi terbarukan, listrik matahari, PLTS, rooftop PV, fotovoltaik, atap gedung, produki energi, PVWatts
Rancang Bangun Sistem Keamanan Sepeda Motor Dengan GPS Tracker Berbasis Mikrokontroler dan Aplikasi Android
Authors: Mahaputra I Gusti Agung Made Yoga , Agung I G A  Putu Raka , Jasa Lie 
Published: October 2020

Intisari—Sepeda motor adalah salah satu jenis transportasi yang paling banyak digunakan di indonesia. Kekurangan sepeda motor saat ini terletak pada keamanannya. Sistem keamanan sepeda motor dengan GPS Tracker berbasis Mikrokontroler dan Aplikasi Android berfungsi untuk memonitoring dan mengontrol sepeda motor melalui aplikasi Android. Pengujian sistem keamanan dilakukan dengan tiga tes utama. Pengujian alat pengaman sepeda motor dilakukan dengan menguji setiap modul alat. Pengujian aplikasi Android dilakukan dengan menjalankan fungsi monitoring dan kontrol. Pengujian komunikasi dilakukan dengan mengirim perintah dari smartphone ke alat. Berdasarkan hasil pengujian yang telah dilakukan, sistem dapat menjalankan semua perintah. Alat keselamatan sepeda motor dapat berkomunikasi dengan aplikasi android dan dapat mendeteksi koordinat. Operator Simcard memengaruhi waktu pairing pada modul GSM di mana Telkomsel memiliki kecepatan pemasangan 6 detik, M3 memiliki kecepatan 31 detik dan XL memiliki kecepatan 310 detik. Terdapat selisih nilai pembacaan antara Jarak perpindahan sepeda motor sebenarnya dengan jarak perpindahaan sepeda motor pada alat mencapai 4 meter sehingga toleransi keakuratan dari alat adalah kurang lebih 4 meter.
Kata Kunci— GPS NEOM8N, Sepeda Motor, SIM900A, Sistem Keamanan.
Effect of Mulching Techniques and Irrigation Levels on Onion (Allium cepa L.) Growth Parameters Under Drip Irrigation System During Dry Season of Western Ethiopia
Authors: Tolossa Tasisa Temesgen 
Published: October 2020

The increasing scarcity and competition for irrigation water entails adoption of innovative
practices that increase efficient water use. The objective of this research was to compare different mulching techniques and investigated the combined effect of irrigation levels under drip irrigation system based on the parametric evaluation system in western part of Ethiopia during the 2018 dry season. A factorial combination of five levels of water (namely 100%, 80% and 70%, 60% and 50%ETc) combined with three mulch treatments (namely, Normal Mulch (NM), Straw Mulch (SM) and Plastic Mulch (PM)) with three replications. The analysis of variance showed that, days to 50% maturity, leaf number per plant, mean leaf length, plant height and leaf area were significantly affected by the main effects of deficit irrigation levels and mulching materials. The interaction effects of deficit irrigation levels and mulching materials significantly influenced plant height, number of leaf per plant, plant height, Leaf length and Leaf area of the onion. The present study suggests that, in water scarce area, farmers are advised to adopt deficit irrigation level with 80% ETc under plastic mulch. It is important even to undertake similar studies at different seasons with different varieties in consideration of their cost benefit analysis. However, if water is not a limiting factor, farmers are advised to apply full irrigation water application under plastic mulch.
LEVANTAMENTO DA AVIFAUNA PRESENTE EM PROPRIEDADE PARTICULAR NO MUNICÍPIO DE SAUDADE DO IGUAÇU, PARANÁ
Authors: Bratti Bruna Caroline , Treco Fernando Rodrigo 
Published: October 2020

RESUMO:O Brasil possui uma das mais ricas avifaunas do mundo. Vários estudos com esse grupo vêm sendo realizados na Região Sudoeste do Paraná e também no Brasil. No município de Saudade do Iguaçu não há estudos científicos sobre a comunidade de aves o que evidencia a importância do presente estudo. Objetivou-se realizar um levantamento da avifauna presente em uma propriedade rural do município de Saudade do Iguaçu, Sudoeste do Paraná. O estudo foi realizado de novembro de 2016 a agosto de 2018. A área de estudo localiza-se em uma propriedade particular na Linha Biguá, que corresponde a 11 hectares; na área predominando a pecuária e a agricultura como atividade econômica e encontram-se fragmentos de mata secundária. Foram realizadas técnicas de observações visuais para identificação das espécies, bem como o registro fotográfico das mesmas. Ao total foram registradas 31 espécies distribuídas em 20 famílias e 10 ordens, as aves com maior frequência foram Vanellus chilensis (quero-quero) com 43,75%, e as espécies Furnarius rufus (joão-de-barro) com 46,87%, Turdus rufiventris (sabiá-laranjeira) com 46,87%, Sicalis flaveola (canário-da-terra-verdadeiro) com 31,25% e Cacicus haemorrhous (guaxe) com 34%. Esses dados contribuem com os demais estudos realizados no estado do Paraná.PALAVRAS-CHAVE: Avifauna. Saudade do Iguaçu. Aves. Paraná.
Analisis Peningkatan Kepuasan Pelanggan Pada Restoran Bale Rasa Ponorogo
Authors: Santoso Adi 
Published: October 2020

Penelitian ini adalah mengenai analisis peningkatan kepuasan pelanggan Restoran Bale Rasa di Ponorogo. Tujuan dari pelaksanaan penelitian ini adalah yang pertama untuk mengetahui bagaimana pengaruh kualitas pelayanan terhadap kepuasan pelanggan, kedua untuk mengetahui pengaruh interior display terhadap kepuasan pelanggan dan yang ketiga untuk mengetahui pengaruh store layout terhadap kepuasan pelanggan. Obyek dari penelitian ini adalah pelanggan restoran Bale Rasa di Ponorogo. Penelitian ini merupakan penelitian kuantitatif dan survei. Populasi penelitian ini adalah pelanggan Resto Bale Rasa dan sampel yang digunakan dalam penelitian ini berjumlah 100 pelanggan yang dipilih menggunakan metode random sampling. Metode pengambilan data dilakukan dengan menggunakan kuisioner dan dokumentasi. Hasil penelitian ini secara parsial menemukan bahwa variabel kualitas pelayanan dan store layout berpengaruh positif dan signifikan terhadap tingkat kepuasan pelanggan Resto Bale Rasa sedangkan variabel interior display ditemukan tidak berpengaruh signifikan terhadap peningkatan kepuasan pelanggan Resto Bale Rasa.
Representações sociais de relação museu-educação: desafios à formação e à gestão em Campina Grande
Authors: De Oliveira Gonçalves Renata Carlos , Lira André Augusto Diniz 
Published: October 2020

O presente artigo analisa a representação social da relação museu-escola construída por professores do Ensino Fundamental da rede municipal de ensino de Campina Grande – PB. Consideramos os 8 principais museus em atividade dessa cidade e a localização de 8 escolas em seus raios de influência. Coletamos dados junto a 48 participantes dessas escolas, através da Associação Livre de Palavras (ALP) com a palavra-estímulo “Museu”, do questionários e de entrevistas em profundidade realizadas com 5 docentes. A análise da ALP foi realizada exclusivamente pelo Iramuteq, considerando-se a análise repetição de palavras mais frequentes e suas co-ocorrências. Utilizamos a Estatística Descritiva para analisar as questões objetivas. As questões abertas foram analisadas tanto pela análise de conteúdo quanto pelo sofware Iramuteq. Os resultados apontam para o museu como um espaço fundamentalmente associado à história, sendo importante mas, ao mesmo tempo, distante da escola e das suas práticas e desvalorizado por propor prática mecânicas. Essa representação suscita várias questões quanto a formação docente e a gestão da escola, do sistema escolar e dos próprios museus. Palavras-chave: Museus. Escola. Representações Sociais.
Building Facade Arrangement as City Image Optimization
Authors: Andarini Risma 
Published: October 2020

Facade is one of building mass elements which supports street users’s perception [1]. Elements that affect the building facade, namely : harmonization, contrast, materials, textures and colors also support the visual aesthetics perception district into an unforgettable part to recognize a place [3]. The intensity of the building mass such as the Building Coverage Ratio (BCR), Open Space Ratio (OSR), Floor Area Ratio (FAR), Building Height, Scale and Skyline are some physical factors of the street corridor to optimize the image of the city [4]. Kartini Street is one of the main streets in Gresik city center which connects the East with the West region of Gresik. Complexity of existing land use and lack of decisiveness system in Building and Land Use Regulation affected the image of the city in variety of facade. Therefore, optimization of the facade and built environment is very important to support the image of the city [2]. Observations are made to provide data in existing facade, facade tendency and the historical background of the region. From the data analysis, it is found that there are building elements which can be a visual aesthetic element to unify and optimize harmonization of Kartini Gresik street corridor to support the image of Gresik.
Recuperación de suelos sódicos
Authors: Panzardi Claudia A. , Quiroz Norma C. , Erkia Sonia 
Published: October 2020

<p>Este trabajo surgió como una inquietud de un productor del interior del Chaco en el campo del cual se presentaban manchones donde las plantas se veían con un menor crecimiento y desarrollo en comparación al resto del cultivo y había una disminución en el número de plantas. El suelo mostraba un planchado superficial y características de erosión hídrica. Se realizó el muestreo correspondiente a suelos salinos y del resultado de los análisis se pudo diagnosticar que se estaba ante un suelo sódico. La consecuencia de ello se traduce en una dispersión de suelo con consecuente encostramiento que disminuye la entrada del agua al perfil, así como se ve disminuida la aireación y fallas en la emergencia de plántulas luego de la siembra. En adición, valores de pH elevados afectan la disponibilidad de nutrientes para el cultivo. Como solución a esta problemática se aplicó sulfato de calcio (yeso agrícola) en forma granulada, de manera localizada al manchón seguido de una leve incorporación. A los seis meses, se realizó un nuevo muestreo en el lugar comprobándose que el pH había disminuido a valores que no resultaban perjudiciales para el cultivo así como la conductividad eléctrica y el contenido de sodio. El cultivo de girasol presentaba una distribución de plantas uniforme así como en su apariencia.</p>
The development of physical comics handout problem based learning to improve students' creative thinking skills in straight motion students
Authors: Zarvianti Enny , Sahida Desrianti 
Published: October 2020

The development of learning materials from handout by Problem Based Learning (PBL) assisted comics to straight motion of creative thinking skills with valid, practical, and effective has been done. The research and development method is implemented in this work. The 4-D development model was used consist of define, design, development, and disseminate. In the define phase, it was done curriculum, student, and material analysis. In the design phase, it was done by designing learning materials the from handout assisted comics by PBL comprise learning instructional such as lesson plan (RPP), handout, and assessment. In the development phase, test of validity, practicality, and the effectivity of handout were done. Then in the disseminate phase, test of practicalities and effectiveness were done. The result of the study in the define phase about students was obtained that level of creative thinking skills of students of class X IPA 2 are in the low category. The analysis of material was obtained straight motion. In the design phase, it was obtained initial draft of handout by PBL assisted comics that consist of RPP, handout, and assessment. In the development phase, it was obtained handout by PBL assisted comics which has valid criteria (0,86), practically criteria (94%), and effective for cognitive creative thinking skills aspect (76%), effective in improving creative thinking skills (79%) are in the category of very creative, the category character becomes a habit (86%), and skill was (87%). In the disseminate phase, it was obtained effective for cognitive creative thinking skills aspect (76,9%), effective in improving creative thinking skills (78,4%) are in the category of very creative, the category character becomes a habit (84%), and skill was (81,9%).
Вдосконалення методики відбору зразків деревини сосни звичайної (Pinus sylvestris L.) з метою визначення питомої активності 137 Cs
Authors: Krasnov  V. P. , Zhukovskyi  O. V. , Orlov  O. O. 
Published: October 2020

Досліджено розподіл 137Cs у деревині стовбура 80-річної сосни звичайної (Pinus sylvestris L.) у свіжих борах. Встановлено зменшення величини питомої активності 137Cs в деревині, яка сформувалася в ті самі роки, але на різній висоті. Так, величина цього показника в деревині 1997–1993 рр. утворення біля окоренка становила 4 730 ± 348 Бк·кг-1, на висоті 6 м – 3 510 ± 257 Бк·кг-1 (в 1,3 разу менше), на висоті 12 м – 3 330 ± 294 Бк·кг-1 (в 1,4 разу менше) і на висоті 22 м – 2870 ± 148 Бк·кг-1 (в 1,7 разу менше). Подібні закономірності відзначено і в деревині, яка утворилася в інші періоди спостереження: значення питомої активності 137Cs у них зменшуються з висотою. На всіх висотах стовбура в деревині, утвореній протягом 1997–1993 рр., визначено найбільші значення питомої активності радіонукліда; із заглибленням до ядра стовбура цей показник знижується. Біля окоренка величина показника в зовнішньому шарі (1997–1993 рр. утворення) становила 4 730 ± 348 Бк·кг-1, а в центрі стовбура (1923–1927 рр. утворення) – 1 000 ± 117 Бк·кг-1, що є в 4,7 разу меншим. Під час проведення радіоекологічних досліджень для визначення середньої питомої активності 137Cs в деревині стовбура рекомендовано відбирати зразки деревини через 1–2 м вздовж стовбура й визначити середнє з використанням усіх отриманих даних щодо цього показника на всіх висотах стовбура.
Пожежостійкість і постпірогенний відпад соснових лісів лівобережної частини Харківської області за різних рівнів пожежної небезпеки за умовами погоди
Authors: Sydorenko S. H. 
Published: October 2020

Пожежі є одними з найнебезпечніших чинників дестабілізації лісів. Визначення особливостей постпірогенного розвитку сосняків дає змогу пом’якшити негативні наслідки, спричинені лісовими пожежами, та допомогти в прийнятті рішень стосовно ведення господарства в таких лісах. Виявлено, що санітарний стан насаджень залежав від значення комплексного показника пожежної небезпеки (КППН) на момент пожежі та погіршувався у міру його збільшення (r = 0,71; p = 0,05). За вищих значень КППН підвищуються інтенсивність тепловиділення під час пожежі та ступінь вигорання лісової підстилки. Встановлено, що за КППН від 1 500 до 3 000 балів індекс санітарного стану насаджень варіює від II,0 до III,9; частка відпаду сягає 20 %. За подальшого збільшення значень КППН понад 5 000 балів індекс стану насадження через рік після пожежі становить III,5–V,0. З’ясовано, що висота полум’я та висота нагару на стовбурах достовірно не залежать від рівня пожежної небезпеки за умовами погоди. Вдосконалено підходи до прогнозування постпірогенного відпаду на рівні насадження з урахуванням характеристик пожежонебезпечного сезону, ступеня пошкодження дерев у насадженні та його таксаційних характеристик.