bluuebunny/crossref_metadata_2025_split huggingface dataset:
Guardians of the Sacred: The Nuns of Soissons and the Slipper of the Virgin Mary
Authors: Clark Anne L. 
Published: February 2020

What could it mean to a medieval monastic community to own a valuable object? Certainly, property in general was crucial to the survival of a stable community, ideals of poverty and the thirteenth-century Franciscan experiment in radical poverty notwithstanding. More specifically, what did it mean to own not simply a field or mill that generated revenue, but an object that was believed to have power beyond its material qualities? Such objects—saints’ relics and wonder-working images—did of course also generate revenue, but their meaning and role for the monastic community and the wider society could be much richer than that. And what if the monastic community was a convent of nuns, of professed religious women whose lives were shaped not just by the rule they shared with their male counterparts, but also by the codes, both implicit and increasingly explicit, that constrained the range of women's religious activities?Although the first two of these questions—about monastic property and the religious value of sacred objects—have been extensively discussed in scholarship on the Middle Ages, a specific focus on gender in relation to monastic ownership of sacred objects has not been widely examined. My focus on gender here is generated by two salient aspects of religious life in the twelfth century, the period of this study. First, there was an increasing articulation of the priesthood as the sole means of mediating divine presence, and of that priesthood as exclusively male.
Mission Delayed: The Russian Orthodox Church after the Conquest of Kazan'
Authors: Romaniello Matthew P. 
Published: February 2020

Muscovy's active period of eastward expansion began with the conquest of the Khanate of Kazan’ in 1552. By the seventeenth century, one observer claimed that the conquest of Kazan’ was the event that made Ivan IV a tsar and Muscovy an empire. With this victory, the tsar claimed new lands, adding to his subjects the diverse animistic and Muslim population of Turkic Tatars and Chuvashes, and Finno-Ugric Maris, Mordvins, and Udmurts. The conquest of Kazan’ provided both the Metropolitan of Moscow and Ivan IV (the Terrible) an opportunity to transform the image of Muscovy into that of a victorious Orthodox power and to justify the title of its Grand Prince as a new caesar (tsar). Since the conquest was the first Orthodox victory against Islam since the fall of Constantinople, commemorations of it were immediate, including the construction of the Church of the Intercession by the Moat (St. Basil's) on Red Square.The incorporation of the lands and peoples of Kazan’ has served traditionally to date the establishment of the Russian Empire. Accounts of the conquest have emphasized the victory of Orthodoxy against Islam, with the Russian Orthodox Church and its Metropolitan as the motive force behind this expansion. The conversion of the Muslims and animists of the region is portrayed frequently as automatic, facing little resistance. More recently, scholars have criticized this simplistic account of the conquest by discussing the conversion mission as a rhetorical construct and have placed increasing emphasis on the local non-Russian and non-Orthodox resistance to the interests of the Church and state.
“The Flame of Life Was Kindled in All Animal and Sensitive Creatures”: One Quaker Colonist's View of Animal Life
Authors: Plank Geoffrey 
Published: February 2020

In the winter of 1771, the colonial assembly of Pennsylvania received a petition from voters in Lancaster County asking for the construction of a turnpike from the Susquehanna River to Philadelphia. Supporters of the project believed that the new road would spur economic development, and in support of this claim they cited developments in England. England's turnpikes, they argued, had made long-distance travel efficient and safe, had contributed to an expansion of commerce and manufacturing, and had increased the value of agricultural land. Shortly after these claims were published in thePennsylvania Gazette,John Woolman, a Quaker reformer in Mount Holly, New Jersey, began hearing troubling stories about the English roads. Woolman was best known as an opponent of slavery, but in his writings and travels he had voiced concerns on an array of other economic issues, including exploitative labor relations generally, and the overwork and abuse of animals. In 1772, Woolman was planning to travel in England, and thus he had reason to pay attention to reports about the English roads.One of the innovations of England's turnpike era was the “flying coach.” This was a carriage pulled by a team of six horses, and it achieved efficiency not so much by running fast as by starting early in the morning and going for long hours continuously. Woolman heard that flying coaches could cover one hundred miles in twenty-four hours, and that they “often run over foot people in the dark.”
Rumen function in goats, an example of adaptive capacity
Authors: Giger-Reverdin Sylvie , Domange Céline , Broudiscou Laurent P. , Sauvant Daniel , Berthelot Valérie 
Published: February 2020

AbstractThe aim of this Research Reflection is to describe the basic rumen function of goats and its modification in response to environmental factors, as well as to discuss similarities and differences when compared to other ruminants. In so doing we shall reveal the adaptive capacity of goats to harsh environments. The basic rumen function in goats is similar to other species of ruminants, as stressed by the opportunity to apply the updates of feeding systems for ruminants to goats. The rumen epithelium acts as a protective barrier between the rumen and the host, but it can be damaged by toxic compounds or acidosis. The rumen also plays an important role in water balance, both for dehydration and rehydration. Recent studies show that the microbiota exhibits a high fractional stability due to functional redundancy and resilience, but this needs more investigation. The microbial community structure differs between goats and cows, which explains the difference in sensitivity to milk fat depression following intake of high lipid diets. Goats also differ from other ruminants by their enhanced ability to feed-sort, but as with cows they can suffer from acidosis. Nevertheless, goats can be considered to be very resistant to environmental factors such as water stress, salt stress or heat stress, and this is especially so in some endogenous breeds. They also are able to detoxify tannins, polyphenols and other secondary metabolites. Some new trials involving feeding behaviour, microbiota and omics or approaches by meta-analyses or modelling will improve our knowledge of rumen function in goats.
Apathy predicts rate of cognitive decline over 24 months in premanifest Huntington's disease
Authors: Andrews S. C. , Langbehn D. R. , Craufurd D. , Durr A. , Leavitt B. R. , Roos R. A. , Tabrizi S. J. , Stout J. C. ,   the TRACK-HD Investigators
Published: February 2020

AbstractBackgroundCognitive impairment is a core feature of Huntington's disease (HD), however, the onset and rate of cognitive decline is highly variable. Apathy is the most common neuropsychiatric symptom of HD, and is associated with cognitive impairment. The aim of this study was to investigate apathy as a predictor of subsequent cognitive decline over 2 years in premanifest and early HD, using a prospective, longitudinal design.MethodsA total of 118 premanifest HD gene carriers, 111 early HD and 118 healthy control participants from the multi-centre TRACK-HD study were included. Apathy symptoms were assessed at baseline using the apathy severity rating from the Short Problem Behaviours Assessment. A composite of 12 outcome measures from nine cognitive tasks was used to assess cognitive function at baseline and after 24 months.ResultsIn the premanifest group, after controlling for age, depression and motor signs, more apathy symptoms predicted faster cognitive decline over 2 years. In contrast, in the early HD group, more motor signs, but not apathy, predicted faster subsequent cognitive decline. In the control group, only older age predicted cognitive decline.ConclusionsOur findings indicate that in premanifest HD, apathy is a harbinger for cognitive decline. In contrast, after motor onset, in early diagnosed HD, motor symptom severity more strongly predicts the rate of cognitive decline.
Should we be concerned about stigma and discrimination in people at risk for psychosis? A systematic review
Authors: Colizzi Marco , Ruggeri Mirella , Lasalvia Antonio 
Published: February 2020

AbstractBackgroundPrevious studies have provided initial evidence that people at risk for psychosis (PR) suffer from stigma and discrimination related to their condition. However, no study has systematically reviewed stigma and discrimination associated with being at PR and the potential underlying mechanisms.MethodsThis work aimed to systematically review all studies addressing stigma and discrimination in PR people in order to assess: (1) the occurrence of this phenomenon and its different components (public, internalized, perceived, and labeling-related), (2) whether stigma affects outcomes of the PR state, and (3) whether other factors modulate stigma among PR individuals.ResultsThe reviewed studies (n = 38) widely differ in their design, methodological quality, and populations under investigation, thus limiting direct comparison of findings. However, converging evidence suggests that the general public endorses stigmatizing attitudes towards PR individuals, and that this is more frequent in people with a low educational level or with no direct experience of the PR state. PR individuals experience more internalized stigma and perceive more discrimination than healthy subjects or patients with non-psychotic disorders. Further, PR labeling is equally associated with both positive (e.g. validation and relief) and negative effects (e.g. status loss and discrimination). Moreover, stigma increases the likelihood of poor outcome, transition to full-psychosis, disengagement from services, and family stigma among PR individuals. Finally, very limited evidence awaiting replication supports the efficacy of cognitive therapies in mitigating the negative effects of stigma.ConclusionsEvidence confirms previous concerns about stigma and its negative consequences for PR individuals, thus having important public health implications.
The formation of collective, political and cultural memory in the Middle Bronze Age: foundation and termination rituals at Toprakhisar Höyük
Authors: Akar Murat , Kara Demet 
Published: February 2020

AbstractConstructing and deconstructing public spaces in second-millennium BC Anatolia, the Near East and the Levant was not only a collaborative physical act but also involved deeply embodied ritual symbolism. This symbolism is materialised in the practice of conducting public foundation and termination rituals that unified individual memories in space and time, transforming the physical act into a collective memory: a process that contributed to the formation of political and cultural memory. The recent rescue excavations conducted by the Hatay Archaeological Museum at the hinterland site of Toprakhisar Höyük in Altinözü (in the foothills above the Amuq valley) add to the understanding of the practice of foundation and termination rituals during the Middle Bronze Age and how these moments may have contributed to the political and cultural memory of a rural community living away from the centre. The practice of foundation/termination rituals is archaeologically documented by caches of artefacts from votive contexts stratigraphically linked to the construction and termination of a Middle Bronze Age administrative structure.
Paediatric cardiomyopathies: echocardiographic diagnosis, clinical profile, and demographic characteristics: the experience of a tertiary referral centre for Latin American paediatric cardiology
Authors: Huertas-Quiñones Víctor M. , Mestra Camilo F. , Peña-Trujillo Valeria , Gallo-Bernal Sebastián , Villaveces Mariana , Alarcón-Forero Laura C. 
Published: February 2020

AbstractBackground:Although multiple studies have been conducted in the adult population, there is a vast knowledge gap regarding the epidemiologic characteristics of cardiomyopathies in the paediatric population. This issue is even more crucial when the precarious situation of medical research in Latin America is considered. Given the potential impact that these disorders could have on Latin American health systems, a comprehensive epidemiologic study regarding the clinical profile and sociodemographic characteristics of these patients will influence the way we approach paediatric cardiomyopathies.Methods:An observational retrospective study was conducted at a tertiary referral centre for Colombian and Latin American paediatric cardiology. We analysed all cases of primary cardiomyopathies in children younger than 18 years of age who presented at our institution between 2010 and 2016. Cases of cardiomyopathies were classified according to World Health Organization guidelines.Results:From a total of 29,533 children who attended our institution during the study period, 89 new cases of primary cardiomyopathies were identified. The median age at diagnosis was 11 years (interquartile range 4–9). Dilated cardiomyopathy accounted for 57.3% (n = 51) of cases; hypertrophic cardiomyopathy, 12.3% (n = 11); restrictive cardiomyopathy, 8.9% (n = 8); non-compacted cardiomyopathy, 7.8% (n = 7); arrhythmogenic ventricular cardiomyopathy, 6.7% (n = 6); and unspecified cardiomyopathy, 6.7% (n = 6). Heart failure was observed in 53.93% of the patients. The overall mortality was 12.36% (n = 11), which included two of eight patients who underwent cardiac transplantation.
The Uniform Dataset 3.0 Neuropsychological Battery: Factor Structure, Invariance Testing, and Demographically Adjusted Factor Score Calculation
Authors: Kiselica Andrew M. , Webber Troy A. , Benge Jared F. 
Published: February 2020

AbstractObjective:The goals of this study were to (1) specify the factor structure of the Uniform Dataset 3.0 neuropsychological battery (UDS3NB) in cognitively unimpaired older adults, (2) establish measurement invariance for this model, and (3) create a normative calculator for factor scores.Methods:Data from 2520 cognitively intact older adults were submitted to confirmatory factor analyses and invariance testing across sex, age, and education. Additionally, a subsample of this dataset was used to examine invariance over time using 1-year follow-up data (n= 1061). With the establishment of metric invariance of the UDS3NB measures, factor scores could be extracted uniformly for the entire normative sample. Finally, a calculator was created for deriving demographically adjusted factor scores.Results:A higher order model of cognition yielded the best fit to the data χ2(47) = 385.18,p< .001, comparative fit index = .962, Tucker-Lewis Index = .947, root mean square error of approximation = .054, and standardized root mean residual = .036. This model included a higher order general cognitive abilities factor, as well as lower order processing speed/executive, visual, attention, language, and memory factors. Age, sex, and education were significantly associated with factor score performance, evidencing a need for demographic correction when interpreting factor scores. A user-friendly Excel calculator was created to accomplish this goal and is available in the online supplementary materials.Conclusions:The UDS3NB is best characterized by a higher order factor structure. Factor scores demonstrate at least metric invariance across time and demographic groups. Methods for calculating these factors scores are provided.
A qualitative study exploring men’s experience of sexual dysfunction as a result of radiotherapy and androgen deprivation therapy to treat prostate cancer
Authors: Kinnaird W. , Stewart-Lord A. 
Published: February 2020

AbstractAim:Sexual dysfunction is a common side effect of external beam radiotherapy (EBRT) and androgen deprivation therapy (ADT) to treat prostate cancer. Men are likely to experience erectile dysfunction, low libido, ejaculatory problems and penile shortening. This qualitative study explored men’s perceptions of sexual dysfunction, including factors such as self-perception, relationships and information and support needs.Methods:Semi-structured interviews were carried out with n = 8 men living 18–30 months after EBRT ± ADT. The interviews were transcribed and thematic analysis was carried out.Results:All men experienced sexual dysfunction following treatment. The main themes arising were: (i) priorities—sexual issues were not a priority when making treatment decisions, (ii) information and support—men described a lack of information and support about sexual dysfunction and (iii) impact—sexual dysfunction impacted on their self-perception and relationships.Findings:Men undergoing EBRT/ADT for prostate cancer may be affected by post-treatment changes in sexual function in a range of ways. This study suggests that they would benefit from early and wide-ranging information and support on sexual dysfunction, even if they do not consider it as a priority. Candid discussions about self-perception and relationships, as well as physical changes, may equip them to cope with post-treatment changes.
Building, Dwelling, Dying: Architecture and History in Pakistan
Authors: Moffat Chris 
Published: February 2020

AbstractThere is a long history of scholars finding in architecture tools for thinking, whether this is the relationship between nature and culture in Simmel's ruins, industrial capitalism in Benjamin's Parisian arcades, or the rhythms of the primordial in Heidegger's Black Forest farmhouse. But what does it mean to take seriously the concepts and dispositions articulated by architects themselves? How might processes of designing and making constitute particular forms of thinking? This article considers the words and buildings of Lahore-based architect Kamil Khan Mumtaz (b. 1939) as an entry point into such questions. It outlines how professional architecture in Pakistan has grappled with the unsettled status of the past in a country forged out of two partitions (1947 and 1971). Mumtaz's work and thought—engaging questions of tradition, authority, craft and the sacred—demonstrates how these predicaments have been productive for conceptualizing time, labor and the nature of dwelling in a postcolonial world.
Understanding how maternal social and biological factors are related to fetal growth in an urban South African cohort
Authors: Prioreschi Alessandra , Wrottesley Stephanie V. , Said-Mohamed Rihlat , Nyati Lukhanyo , Newell Marie-Louise , Norris Shane A. 
Published: February 2020

AbstractThe aim of this study was to identify social and biological drivers of fetal growth by examining associations with household, preconception, and pregnancy factors in a cohort from Soweto, South Africa. Complete data and ultrasound scans were collected on 519 women between 2013 and 2016 at 6 time points during pregnancy (<14, 14–18, 19–23, 24–28, 29–33 weeks, and 34–38 weeks). Household-level factors, preconception health, baseline body mass index (BMI), and demographic data were collected at the first visit. During pregnancy, gestational weight gain (GWG; kg/week) was calculated. At 24–28 weeks of gestation, oral glucose tolerance test was used to determine gestational diabetes mellitus (GDM) status, and hypertension status was characterised. Longitudinal growth in head circumference, abdominal circumference, biparietal diameter, and femur length were modelled using the Superimposition by Translation and Rotation, a shape-invariant model which produces growth curves against gestational age. A priori identified exposure variables were then included in a series of sex-stratified hierarchical regression models for each fetal growth outcome. No household-level factors were associated with fetal growth. Maternal BMI at baseline was positively associated with all outcome parameters in males and females. Both GWG (in males and females) and GDM (in males) were significant positive predictors of abdominal growth. Males showed more responsiveness to abdominal growth, while females were more responsive to linear growth. Thus, fetal growth was largely predicted by maternal biological factors, and sexual dimorphism in the responsiveness of fetal biometry to biological exposures was evident.
Telecoupling through tomato trade: what consumers do not know about the tomato on their plate
Authors: Ibarrola-Rivas Maria-Jose , Castro Antonio J. , Kastner Thomas , Nonhebel Sanderine , Turkelboom Francis 
Published: February 2020

Non-technical abstract
A large share of our food comes from international supply food chains that are difficult to trace. Therefore, consumers are not aware of their environmental and social effects. We analysed the tomato supply system for Germany. Tomatoes consumed in Germany are produced either in The Netherlands by Polish workers and using large amounts of energy, or in Spain by West African workers and depleting the aquifer. The analysis shows the long-distance effects of food consumption that should be considered when designing strategies for a sustainable global food system. Comparable results can be expected for other food products traded around the world.
Appraisal of Data Assimilation Techniques for Dynamical Downscaling of the Structure and Intensity of Tropical Cyclones
Authors: Malakar Pampi , Kesarkar Amit P. , Bhate Jyoti , Deshamukhya Atri 
Published: February 2020

AbstractThe dynamical downscaling technique is used for the understanding of physical mechanisms associated with the atmospheric phenomena. We have developed high‐resolution analysis (6 km) for three tropical cyclones (TCs), namely, Phailin (2013), Nilofar (2014), and Chapala (2015) originated over the North Indian Ocean using the dynamical downscaling approach. The study aimed at the identification of appropriate methodology for generating analysis so that it becomes useful for identifying the role of environmental and internal dynamics on intensification processes and structural changes of TCs. The simulations using Weather Research and Forecasting model and four‐dimensional variational (4DVAR), hybrid three‐dimensional ensemble‐variational (3DEnVAR), and a hybrid four‐dimensional ensemble‐variational (4DEnVAR) data assimilation (DA) techniques are compared. The impact of DA is quantified by comparing errors in position, minimum sea level pressure, and maximum wind speed with the best track data set of India Meteorological Department. The intensities of TCs simulated by three downscaling methods are validated in terms of changes in minimum sea level pressure, maximum surface winds, and boundary layer and middle tropospheric relative humidity. The skills scores, namely, equitable threat score, false alarm ratio, the probability of detection, and biases (BIAS), are calculated to identify the best suitable DA technique. It is found that the hybrid DA techniques improve the overall quality of analysis compared to those developed using only variational DA techniques. The simulation using the hybrid 4DEnVAR DA technique is found to be better for simulation of the track, intensity changes, and structural characteristics of TCs.