bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accuracy of three-dimensional photogrammetry and cone beam computed tomography based on linear measurements in patients with facial deformities
Authors: Zhao Zhenqi , Xie Lizhe , Cao Dan , Izadikhah Iman , Gao Pengcheng , Zhao Yang , Yan Bin 
Published: August 2020

Objectives: This study was aimed to investigate the accuracy of soft-tissue measurements obtained by two imaging modalities, three-dimensional (3D) photogrammetry and cone beam CT (CBCT) when confounded by influence factors (facial deformities and partitions). Methods: 60 wax facial models from facially deformed patients were captured by 3D photogrammetry and CBCT. 19 linear distances on each image were measured and juxtaposed to reference values attained via a coordinate-measuring machine (CMM) as the gold-standard. Paired t-tests were used to compare linear accuracy of the test and reference systems. The influence of deformities and partitions (created by dividing the face with three vertical and five horizontal lines) on the measurement errors were analyzed by independent sample t-test and one-way ANOVA. Results: Statistically significant differences were found between linear accuracy of the test and reference systems. The test values obtained by 3D photogrammetry were closer to the reference values than CBCT’s. 3D photogrammetry’s measurement errors were significantly higher in deformed areas, unlike CBCT’s. Both systems reported significantly lower errors within partitions 8 and 13 compared to other partitions; for CBCT, aside from partitions 8 and 13, the differences in the errors for partitions 6 and 10 were significant compared to partitions 8, 12, 13, 14. Conclusion: 3D photogrammetry showed a higher linear accuracy than CBCT in patients with facial deformities due to protuberances. Facial reconstruction by both test modalities was significantly influenced in different facial partitions, but facial deformities extensively affected the results from 3D photogrammetry.
HbA1c – A predictor of dyslipidemia in type 2 Diabetes Mellitus
Authors: Kidwai Saera Suhail , Nageen Ayesha , Bashir Farhat , Ara Jamal 
Published: August 2020

Objective: This study was aimed to determine the predictive value of HbA1c in detecting dyslipidemia in patients with Type-2 Diabetes Mellitus.
Methods: A total of 142 consecutive patients of Type-2 diabetes mellitus were recruited in this study after informed consent. The study was conducted for 6 months from January 2019 – June 2019 in Creek General Hospital, Korangi, Creek, Karachi. Demographic data and detailed history was taken. A complete systemic examination was done for any complications or co-morbids present and related investigations were performed including Fasting lipid profile (CHO, TG’s, HDL, LDL, CHO/HDL), serum HbA1c, Creatinine and ECG. Data is analyzed on SPSS 16 for mean, frequencies and correlations. Pearsons Chi square test is used for analyses of Correlation
Results: In a total of 142 Type-2 diabetic patients 39(27.5%) were Males and 103(72.5%) were females with a male to female ratio of 1: 2.6. Mean age was 54.9yrs ± 10.7SD. Mean duration of diabetes was 7.37yrs ±5.64 SD years. Mean BMI is 26.8 ± 3.67kg/m2. 27(19.01%) patients had HbA1c ≤ 7% whereas 115(80.9%) had >7%. 81(57.04%) patients had dyslipidemia. HbA1c exhibited direct correlations with BMI, cholesterol, TG’s and LDL and inverse correlation with HDL with significant P value of <.05. TG’s were found significantly higher in females when compared with male patients. In addition, Metabolic syndrome also showed a strong correlation with increasing HbA1c levels especially in female gender (P0.001).
Conclusion: The results of our study indicates that HbA1c can be used not only as a useful biomarker of long-term glycaemic control but also a good predictor of lipid profile.
doi: https://doi.org/10.12669/pjms.36.6.2000
How to cite this:Kidwai SS, Nageen A, Bashir F, Ara J. HbA1c – A predictor of dyslipidemia in type 2 Diabetes Mellitus. Pak J Med Sci. 2020;36(6):1339-1343. doi: https://doi.org/10.12669/pjms.36.6.2000
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Effects of stretching exercises on human gait: a systematic review and meta-analysis
Authors: Vialleron Thomas , Delafontaine Arnaud , Ditcharles Sebastien , Fourcade Paul , Yiou Eric 
Published: August 2020

Background: Stretching is commonly used in physical therapy as a rehabilitation tool to improve range of motion and motor function. However, is stretching an efficient method to improve gait, and if so, for which patient category? Methods: A systematic review of randomized and non-randomized controlled trials with meta-analysis was conducted using relevant databases. Every patient category and every type of stretching programs were included without multicomponent programs. Data were meta-analysed where possible. Estimates of effect sizes (reported as standard mean difference (SMD)) with their respective 95% confidence interval (95% CI) were reported for each outcome. The PEDro scale was used for the quality assessment. Results: Twelve studies were included in the analysis. Stretching improved gait performance as assessed by walking speed and stride length only in a study with a frail elderly population, with small effect sizes (both SMD= 0.49; 95% CI: 0.03, 0.96; PEDro score: 3/10). The total distance and the continuous walking distance of the six-minute walking test were also improved only in a study in an elderly population who had symptomatic peripheral artery disease, with large effect sizes (SMD= 1.56; 95% CI: 0.66, 2.45 and SMD= 3.05; 95% CI: 1.86, 4.23, respectively; PEDro score: 5/10). The results were conflicting in healthy older adults or no benefit was found for most of the performance, spatiotemporal, kinetic and angular related variables. Only one study (PEDro score: 6/10) showed improvements in stance phase duration (SMD=-1.92; 95% CI: -3.04, -0.81), swing phase duration (SMD=1.92; 95 CI: 0.81, 3.04), double support phase duration (SMD= -1.69; 95% CI: -2.76, -0.62) and step length (SMD=1.37; 95% CI: 0.36, 2.38) with large effect sizes. Conclusions: There is no strong evidence supporting the beneficial effect of using stretching to improve gait. Further randomized controlled trials are needed to understand the impact of stretching on human gait.
New technologies to improve healthcare in low- and middle-income countries: Global Grand Challenges satellite event, Oxford University Clinical Research Unit, Ho Chi Minh City, 17th-18th September 2019
Authors: Ngoc Dinh Minh , Nygate Joseph , Hoang Minh Tu Van , Thwaites C. Louise ,   Global Grand Challenges Event Vietnam Group
Published: August 2020

We report the outputs of a satellite event in Ho Chi Minh City, Vietnam, organized as part of the “2nd Global Grand Challenges of Engineering Summit”. The event considered challenges and potential solutions for improving low- and middle-income country (LMIC) healthcare systems, with particular reference to critical care. Participants from key regional and local stakeholders in healthcare and engineering discussed how new advances in technology, especially in the field of Artificial Intelligence, could be of potential benefit. This article summarizes the perspectives and conclusions of a group of key stakeholders from LMICs across South and South East Asia.
Una Aproximación desde la Escuela Austriaca a la RSE (responsabilidad social empresarial)
Authors: Chavarro M. Fernando 
Published: August 2020

Por cambios ocurridos en el entorno de las organizaciones, como la globalización de los mercados, el aumento de la repercusión social, la contribución al desarrollo de las comunidades, en las que participan las empresas por medio de prácticas y acciones que permiten el enriquecimiento económico, el bienestar social, la protección y promoción del medioambiente, estas se han visto en la necesidad de incorporar nuevas prácticas de RSE; y desde luego para lograrlo, se deben Identificar las diferencias conceptuales sobre la RSE entre las teorías convencionales y el pensamiento de la escuela de pensamiento Austriaca; por lo que en este documento se considera tener presente algunas acepciones teóricas de la praxeología, la responsabilidad empresarial RSE y la acción humana, para llegar a determinar una aproximación a la interpretación de la RSE desde la praxeología.
Pessary offer documentation in women undergoing surgery for pelvic organ prolapse at a tertiary care hospital
Authors: Masood Zubaida , Imtiaz Rahila , Husain Samia , Husain Sonia , Izhar Rubina 
Published: August 2020

Background: Women report similar functional outcomes after pessary treatment or surgery for pelvic organ prolapse (POP). Aims: To assess the documentation of pessary counselling in women who underwent surgery for POP. Methods: This was a retrospective cohort study conducted on women who underwent hysterectomy for prolapse. The primary outcome measure was documentation regarding offer of pessary. ‘Pessary offer’ was defined as documentation that clearly stated that the care provider offered pessary to the patient. Findings: Over the study period, 81 hysterectomies took place for POP; pessary offer was documented for only 19 (23.5%) case records. Characteristics significantly associated with pessary offer were history of chronic cough (P=0.031), previous pelvic surgery (P<0.001), no secondary indication for surgery (P=0.012), concomitant surgery performed other than hysterectomy (P=0.046), age range (P<0.001) and BMI range (P<0.001). Conclusion: Pessary offer was documented in less than quarter of cases. This denotes a need to strengthen documentation of offer, counselling for pessary, or both of these.
Three-parameter measurement optical fiber sensor based on a hybrid structure
Authors: Nan Tong , Liu Bo , Wu Yongfeng , Mao Yaya , Wang Junfeng , Zhao Lilong , Sun Tingting , Wang Jin , Han Yang 
Published: August 2020

We have proposed a hybrid-structured optical fiber sensor that can measure curvature, temperature, and transverse load. The hybrid structure is made by fusing a section of hollow-core fiber (HCF) between an air bubble and an up-taper. The air bubble acts as a Fabry–Perot interferometer (FPI) and at the same time serves as excitation for a Mach–Zehnder interferometer (MZI). HCF is used as an anti-resonant reflected optical waveguide (ARROW), which periodically decreases in the resonant wavelength of the optical transmission spectrum. The transverse load can be measured by demodulating the reflection spectrum of the FPI. By demodulating the wavelength shift of the MZI for temperature sensing and the intensity change of ARROW inclination for curvature sensing, the curvature and temperature can be measured simultaneously. The experimental results show that the transverse load sensitivity of the FPI is 1.53 nm/N. The curvature and temperature sensitivities are

33.23

d
B

/

m

−
1

and 20.3 pm/°C, respectively, and the cross-sensitivity is

0.0003

m

−
1

/

∘

C

. Due to its ease of manufacture, low crosstalk, and high sensitivity, the hybrid-structured optical fiber sensor is suitable for multi-parameter measurement applications.
Study of the remediation effects of passivation materials on Pb-contaminated soil
Authors: Liang Shu-Xuan , Xi Xiao-Can , Li Yu-Ru 
Published: August 2020

AbstractThe passivation effects of blast furnace slag, fly ash, corncob biochar, and phosphate fertilizer in Pb-contaminated soil was evaluated against the soil pH, available Pb content, Pb fractions, and bioactivity coefficient. Blast furnace slag and fly ash could increase soil pH, while corncob biochar and phosphate fertilizers lowered soil pH. The available Pb content in the blast furnace slag and phosphate fertilizer treatment groups was significantly lower than in other treatments. Also, blast furnace slag and phosphate fertilizer could significantly convert nonresidual Pb into residual Pb. Combined with the environmental impact after application and cost of the material, it is recommended that blast furnace slag can be used as a passivation agent for low-concentration Pb-contaminated soil.
Stability-indicating HPLC-DAD assay for simultaneous quantification of hydrocortisone 21 acetate, dexamethasone, and fluocinolone acetonide in cosmetics
Authors: Arif Saira , Ata Sadia 
Published: August 2020

AbstractA rapid and specific method was developed for simultaneous quantification of hydrocortisone 21 acetate (HCA), dexamethasone (DEX), and fluocinolone acetonide (FCA) in whitening cream formulations using reversed-phase high-performance liquid chromatography. The effect of the composition of the mobile phase, analysis temperature, and detection wavelength was investigated to optimize the separation of studied components. The analytes were finally well separated using ACE Excel 2, C18 AR column having 150 mm length, 3 mm internal diameter, and 2 µm particle size at 35°C using methanol with 1% formic acid and double-distilled deionized water in the ratio of 60:40 (v/v), respectively, as the mobile phase in isocratic mode. Ten microliters of sample were injected with a flow rate of 0.5 mL/min. The specificity, linearity, accuracy, precision, recovery, limit of detection (LOD), limit of quantification (LOQ), and robustness were determined to validate the method as per International Conference on Harmonization guidelines. All the analytes were simultaneously separated within 8 min, and observed retention times of HCA, DEX, and FCA were 4.5, 5.5, and 6.9 min, respectively. The proposed method showed good linearity with the correlation coefficient, R2 = 0.999 over the range of 1–150 µg/mL for all standards. The linear regression equations were y = 12.7x + 118.7 (r = 0.999) for HCA, y = 12.9x + 106.8 (r = 0.999) for DEX, and y = 12.9x + 96.8 (r = 0.999) for FCA. The LOD was 0.25, 0.20, and 0.08 µg/mL for HCA, FCA, and DEX and LOQ was 2.06, 1.83, and 1.55 µg/mL for HCA, FCA, and DEX, respectively. The recovery values of HCA, DEX, and FCA ranged from 100.7–101.3, 102.0–102.6, and 100.2–102.0%, respectively, and the relative standard deviation for precision (intra- and interday) was less than 2, which indicated repeatability and reproducibility. The novelty of the method was described by forced degradation experimentation of all analytes in the combined form under acidic, basic, oxidative, and thermal stress. The proposed method was found to be simple, rapid, and reliable for the simultaneous determination of HCA, DEX, and FCA in cosmetics.
Design, synthesis and pharmacological profile of (−)-verbenone hydrazones
Authors: Nesterkina Mariia , Barbalat Dmytro , Kravchenko Iryna 
Published: August 2020

AbstractA series of novel (−)-verbenone hydrazones was designed and synthesized via condensation of terpenoid with hydrazides derived from phenoxyacetic acid. The structure of target compounds was confirmed by 1H-NMR and 13C-NMR analysis, Raman and FT-IR spectroscopy, electrospray ionization method and fast atom bombardment (FAB) mass spectrometry. Thermal properties of (−)-verbenone hydrazones 3a–3e were estimated by differential scanning calorimetry and their purity by HPLC coupled to mass spectrometry. Verbenone hydrazones were revealed to exist as Z/E geometrical isomers about C═N bond and cis/trans amide conformers. Verbenone derivatives were estimated as potential anticonvulsant agents after their oral administration against pentylenetetrazole and maximal electroshock-induced seizures in mice. Analgesic effect of hydrazones was studied by topical application on models of allyl isothiocyanate and capsaicin-induced pain. The present findings indicate that verbenone hydrazones contribute to seizure protection both at short (6 h) and long (24 h) time periods by blocking chemical- and electroshock-induced convulsions. Binding of compounds 3a–3e to TRPA1/TRPV1 ion channels was suggested as a feasible mechanism explaining their significant analgesic activity.
PCSK9 concentrations in different stages of subclinical atherosclerosis and their relationship with inflammation
Authors: Tóth Štefan , Olexa Peter , Hertelyová Zdenka , Štefanič Peter , Kopolovets Ivan , Berek Peter , Filip Vladimir , Chakravarty Ryan , Široká Monika , Pella Daniel 
Published: August 2020

AbstractThe aim of this study was to detect the concentrations of PCSK9 in various subclinical stages of atherosclerosis and to highlight its relationship with inflammation. One hundred and fifty-nine healthy patients were divided into three groups, based on the extent of atherosclerotic changes in the carotid artery: a group without identifiable atherosclerosis, cIMT>75‰and an asymptomatic plaque group. The PCSK9 was measured by ELISA and hsCRP by the immunoturbidimetric method. Vascular changes were identified by a carotid ultrasound. PCSK9 was elevated, when comparing the healthy group with the cIMT>75‰group; however, no significant increase was detected between cIMT>75‰and the asymptomatic plaque group. A positive linear correlation of the PCSK9 concentration and atherosclerotic changes was found; however, after the re-analysis in each group, this correlation persisted only in the group with still normal values. Additionally, a significant linear correlation was found between the PCSK9 concentrations and lipid parameters. However, no significant association was found with hsCRP. PCSK9 was found to be elevated only in cIMT>75‰, but not in the later plaque stage. A linear correlation of PCSK9 values was detected only in the group with still reference values. Based on this fact, we assumed the direct linear role of PCSK9 in initiating atherosclerosis; however, in the later phases, the relationship, which highlights other risk factors such as inflammation, is not linear.
New derivatives of a natural nordentatin
Authors: Thant Tin Myo , Aminah Nanik Siti , Kristanti Alfinda Novi , Ramadhan Rico , Aung Hnin Thanda , Takaya Yoshiaki 
Published: August 2020

AbstractNew derivatives were obtained from natural nordentatin (1) previously isolated from the methanol fraction of Clausena excavata by an acylation method. Herein, we report ten new pyranocoumarin derivatives 1a–1j. Their structures were elucidated based on UV-vis, FT-IR, NMR, and DART-MS data. The α-glucosidase inhibition and anticancer activities of nordentatin (1) and its derivatives were also evaluated. The α-glucosidase inhibition assay exhibited that the derivatives 1b, 1d, 1e, 1f, 1h, 1i, and 1j possess higher inhibitory activity for α-glucosidase with IC50 values of 1.54, 9.05, 4.87, 20.25, 12.34, 5.67, and 2.43 mM, whereas acarbose was used as the positive control, IC50 = 7.57 mM. All derivatives exhibited a weak cytotoxicity against a cervical cancer (HeLa) cell line with the IC50 between 0.25 and 1.25 mM. They also showed moderate to low growth inhibition of a breast cancer (T47D) cell line with IC50 values between 0.043 and 1.5 mM, but their activity was lower than that of the parent compound, nordentatin (1) (IC50 = 0.041 mM).
Can Foot Anthropometry Predict Vertical Jump Performance?
Authors: Hawley Victoria S. , Gurchiek Reed D. , van Werkhoven Herman 
Published: August 2020

Abstract
Hawley, VS, Gurchiek, RD, and van Werkhoven, H. Can foot anthropometry predict vertical jump performance? J Strength Cond Res 36(7): 1860–1865, 2022—Vertical jumping is an important element of many sporting activities, and whether anthropometric adaptations can predict jumping performance is of interest. Few studies have specifically considered anthropometric measures of the foot and its link to performance. Furthermore, previous studies have mainly focused on a male subject pool, and whether relationships are consistent across sexes is unclear. The purpose of this study was to investigate relationships between common anthropometric measures, as well as specific foot measures, and jump performance in men and women. Anthropometric measures of 21 men (age: 22.0 ± 1.5 years; stature: 181.4 ± 6.3 cm; body mass: 85.6 ± 9.4 kg) and 21 women (age: 21.2 ± 1.8 years; stature: 166.1 ± 7.5 cm; body mass: 61.4 ± 11.4 kg) were taken before performing 3 maximal countermovement jumps (CMJs). Correlational analysis was used to determine relationships between anthropometric measures and CMJ height (a priori significance set at p≤ 0.05, effect size: small >0.1; medium >0.3; large >0.5). There was no significant correlation between anthropometric variables and CMJ height for men, whereas for women, mass (r = −0.585, p = 0.005, large effect), foot length (r = −0.533, p = 0.013, large effect), and toe length (r = −0.604, p = 0.004, large effect) showed significant negative correlations with CMJ height. The unexpected result that smaller feet and toes predicted higher jumps for women warrants further investigation. Furthermore, these results highlight the need to incorporate diverse subject pools, and a need for caution when generalizing across sexes.
Tritium measurement using a photo-stimulable phosphor BaFBr(I):Eu2+ plate
Authors: Ohuchi H. , Hatano Y. 
Published: August 2020

Abstract
Tritium measurement is indispensable for the fuel- processing systems of deuterium-tritium (DT)-fusion facilities. A new approach to detect tritium in regions deeper than the escape depth of beta-rays from tritium is being developed using an imaging plate (IP). The measurement principle of this approach is to observe bremsstrahlung X-rays induced by the tritium beta-rays. An IP made of europium-doped BaFBr(I), a photostimulated luminescence (PSL) material, is a two-dimensional radiation sensor. In the present study, the characteristics of this IP for measuring tritium by detecting bremsstrahlung X-rays, in particular a fading effect and the energy dependence of PSL sensitivities, are examined.
Lanthanide and actinide extractions with cobalt bis(dicarbollide) ion derivatives covalently bonded to diglycolyl diamide platform
Authors: Lučaníková M. , Selucký P. , Rais J. , Grüner B. , Kvíčalová M. 
Published: August 2020

Abstract
The separation of minor actinides from high-level waste (HLW) remains a difficult problem. A wide series of compounds based on two cobalt bis(dicarbollide) ions [(1,2-C2B9H10)(1′,2′-C2B9H11)-3,3′-Co(III)]− (1) covalently bonded to a diglycolyl amide platform via diethyleneglycol connectors was prepared by reaction of the diglycolic acid dichloride with various ammonium derivatives of the ion 1 with the aim to develop new class of extractants for trivalent radionuclides from acidic waste solutions. The extractants of general formulation [{(N,N-(8-CH2-CH2O)2-1,2-C2B9H10)(1′,2′-C2B9H11)-3,3′-Co)(N,N′-R)NCOCH2}2-O]Na2 differed in substitution on the amidic nitrogen (by e.g. butyl-, hexyl-, octyl-, t-octyl-, dodecyl-, benzyl-groups). Compounds were characterized by combination of 11B, 1H and 13C NMR spectroscopy, ESI-MS, HPLC, and TLC RF. The purity of all species was better than 98%. Most of the compounds proved to be very efficient extraction agents and enabled effective extraction of europium(III) and americium(III) from nitric acid solutions. The recovery of the trivalent radionuclides from the loaded organic phase was possible by using ammonium citrate or even better by using solution of ammonium citrate and ammonium DTPA (diethylenetriamine pentaacetate).
Separation of Am(III), Cm(III), and Cf(III) using capillary electrophoresis
Authors: Kikunaga H. , Yoshimura T. , Kuribayashi T. , Kitamoto Y. , Takahashi N. , Haba H. , Ezaki Y. , Enomoto S. , Mitsugashira T. , Shinohara A. 
Published: August 2020

Abstract
Trivalent actinides Am(III), Cm(III), and Cf(III) were successfully separated for the first time using capillary electrophoresis in 2-hydroxyisobutyric acid/acetic acid. It was found that the ionic radius was primarily important for separation of trivalent actinides as well as lanthanides in this condition. The stability constants of the Am(III) complexes with 2-hydroxyisobutyrate were estimated using the correlations between the molar fraction ratio of lanthanides and their ionic radii.