bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physicochemical quality maintenance and bioactive compounds enhancement of Thai guava fruit cv. ‘Kim Ju’ by using combinative hot water and methyl jasmonate immersion
Authors: Yuranan Kernprie Suriyan Supapvanich, , Boonyaritthongchai Panida , Techavuthiporn Chairat , Tepsorn Racha , Youryon Pannipa 
Published: January 2020

Postharvest life of Thai guava fruits is limited due to skin damage and physicochemical changes during cold storage. Both methyl jasmonate (MeJA) and heat treatments are potential approaches maintaining postharvest quality of fruits. Thus, the aim of this work was to investigate the effects of hot water and MeJA immersion on physicochemical quality of ‘Kim Ju’ guava fruit during storage at 12 ± 1 °C for 18 d. The fruit were immersed in hot water at 40 °C for 30 min (H), 0.1 mM MeJA for 10 min (0.1 mM MeJA) or H followed by 0.1 mM MeJA (H + 0.1 mM MeJA) and untreated fruit were used as control. The determined parameters were visual appearance, colour, texture, pectin substances, antioxidant activities, bioactive compounds and antioxidant enzymes activities. The results showed that H + 0.1 mM MeJA treatment maintained visual appearance and colour as compared to 0.1 mM MeJA, H or control treatment, consequently. The treatment of H + 0.1 mM MeJA retarded softening according to the inhibition of soluble pectin increase and insoluble pectin decrease. The treatment enhanced the both antioxidant and free radical scavenging activities as compared to control. These were accompanied with the increments of bioactive compounds such as ascorbic acid, total phenols, flavonoids and peroxidase activity and the retardation of catalase activity decrease. In conclusion, the H + 0.1 mM MeJA treatment could maintain postharvest qualities involving visual appearance and texture and enhanced nutritional value of guava fruit during cold storage.
Highly Efficient and Tunable Filtering of Electrons' Spin by Supramolecular Chirality of Nanofiber‐Based Materials
Authors: Kulkarni Chidambar , Mondal Amit Kumar , Das Tapan Kumar , Grinbom Gal , Tassinari Francesco , Mabesoone Mathijs F. J. , Meijer E. W. , Naaman Ron 
Published: January 2020

AbstractOrganic semiconductors and organic–inorganic hybrids are promising materials for spintronic‐based memory devices. Recently, an alternative route to organic spintronic based on chiral‐induced spin selectivity (CISS) is suggested. In the CISS effect, the chirality of the molecular system itself acts as a spin filter, thus avoiding the use of magnets for spin injection. Here, spin filtering in excess of 85% in helical π‐conjugated materials based on supramolecular nanofibers at room temperature is reported. The high spin‐filtering efficiency can even be observed in nanofibers assembled from mixtures of chiral and achiral molecules through chiral amplification effect. Furthermore and most excitingly, it is shown that both “up” and “down” orientations of filtered spins can be obtained in a single enantiopure system via the temperature‐dependent helicity (P and M) inversion of supramolecular nanofibers. The findings showcase that materials based on helical noncovalently assembled systems are modular platforms with an emerging structure–property relationship for spintronic applications.
Viewpoint: Homeostasis as Inspiration—Toward Interactive Materials
Authors: Lerch Michael M. , Grinthal Alison , Aizenberg Joanna 
Published: January 2020

AbstractHomeostatic systems combine an ability to maintain integrity over time with an incredible capacity for interactive behavior. Fundamental to such systems are building blocks of “mini‐homeostasis”: feedback loops in which one component responds to a stimulus and another opposes the response, pushing the module to restore its original configuration. Particularly when they cross time and length scales, perturbation of these loops by external changes can generate diverse and complex phenomena. Here, it is proposed that by recognizing and implementing mini‐homeostatic modules—often composed of very different physical and chemical processes—into synthetic materials, numerous interactive behaviors can be obtained, opening avenues for designing multifunctional materials. How a variety of controlled, nontrivial material responses can be evoked from even simple versions of such synthetic feedback modules is illustrated. Moreover, random events causing seemingly random responses give insights into how one can further explore, understand and control the full interaction space. Ultimately, material fabrication and exploration of interactivity become inseparable in the rational design of such materials. Homeostasis provides a lens through which one can learn how to combine and perturb coupled processes across time and length scales to conjure up exciting behaviors for new materials that are both robust and interactive.
Chemodivergent Preparation of Various Heterocycles via Phase‐Transfer Catalysis: Enantioselective Synthesis of Functionalized Piperidines
Authors: Bertuzzi Giulio , Silvestrini Filippo , Moimare Pierluigi , Pecorari Daniel , Mazzanti Andrea , Bernardi Luca , Fochi Mariafrancesca 
Published: January 2020

AbstractIn this work, a new chemodivergent domino approach for the preparation of various saturated heterocycles, based on phase‐transfer catalysis (PTC), is presented. The versatile nature of doubly electrophilic substrates, showing both a Michael acceptor and a ketone, tethered by a heteroatom, enables three different domino reaction pathways. The nucleophile dictates the chemoselectivity of the reaction. Sulfa‐Michael/aldol, cyanide addition/oxa‐Michael and Michael/H‐shift/aldol processes, along with the variation of the tethering heteroatom, results in the formation of six different classes of saturated heterocycles. DFT calculations account for the observed chemo‐ and diastereoselectivity of the two most productive processes. Moreover, an extensive investigation on the sulfa‐Michael/aldol pathway was carried out, ultimately leading to the development of a new enantioselective domino approach to multi‐substituted piperidines based on PTC.magnified image
Smart Flexible Electronics‐Integrated Wound Dressing for Real‐Time Monitoring and On‐Demand Treatment of Infected Wounds
Authors: Pang Qian , Lou Dong , Li Shijian , Wang Guangming , Qiao Bianbian , Dong Shurong , Ma Lie , Gao Changyou , Wu Zhaohui 
Published: January 2020

AbstractAs the most frequent wound complication, infection has become a major clinical challenge in wound management. To overcome the “Black Box” status of the wound‐healing process, next‐generation wound dressings with the abilities of real‐time monitoring, diagnosis during early stages, and on‐demand therapy has attracted considerable attention. Here, by combining the emerging development of bioelectronics, a smart flexible electronics‐integrated wound dressing with a double‐layer structure, the upper layer of which is polydimethylsiloxane‐encapsulated flexible electronics integrated with a temperature sensor and ultraviolet (UV) light‐emitting diodes, and the lower layer of which is a UV‐responsive antibacterial hydrogel, is designed. This dressing is expected to provide early infection diagnosis via real‐time wound‐temperature monitoring by the integrated sensor and on‐demand infection treatment by the release of antibiotics from the hydrogel by in situ UV irradiation. The integrated system possesses good flexibility, excellent compatibility, and high monitoring sensitivity and durability. Animal experiment results demonstrate that the integrated system is capable of monitoring wound status in real time, detecting bacterial infection and providing effective treatment on the basis of need. This proof‐of‐concept research holds great promise in developing new strategies to significantly improve wound management and other pathological diagnoses and treatments.
Pancreatic senescence and its clinical manifestations
Authors: Wang Lu , Zheng Songbai 
Published: January 2020

AbstractThe pancreas is a vital organ which has both endocrine and exocrine functions and plays an essential role in food digestion and glucose metabolism. Pancreatic structure and function undergo a series of changes with aging and senescence. Pancreatic exocrine and endocrine function gradually change, which may lead to conditions such as dyspepsia and diabetes mellitus. Hence, clinicians need to be familiar with the characteristics of pancreatic senescence. This article reviews the manifestations of pancreatic senescence and its significance for clinical practice.
Fermi Arcs and DC Transport in Nanowires of Dirac and Weyl Semimetals
Authors: Sukhachov Pavlo O. , Rakov Mykhailo V. , Teslyk Olena M. , Gorbar Eduard V. 
Published: January 2020

AbstractThe transport properties and electron states in cylinder nanowires of Dirac and Weyl semimetals are studied paying special attention to the structure and properties of the surface Fermi arcs. The latter make the electric charge and current density distributions in nanowires strongly nonuniform as the majority of the charge density is accumulated at the surface. It is found that a Weyl semimetal wire also supports a magnetization current localized mainly at the surface because of the Fermi arcs contribution. By using the Kubo linear response approach, the direct current (DC) conductivity is calculated and it is found that its spatial profile is nontrivial. By explicitly separating the contributions of the surface and bulk states, it is shown that when the electric chemical potential and/or the radius of the wire is small, the electron transport is determined primarily by the Fermi arcs and the electrical conductivity is much higher at the surface than in the bulk. Due to the rise of the surface‐bulk transition rate, the relative contribution of the surface states to the total conductivity gradually diminishes as the chemical potential increases. In addition, the DC conductivity at the surface demonstrates noticeable peaks when the Fermi level crosses energies of the surface states.
Understanding the Origin of Highly Selective CO2 Electroreduction to CO on Ni,N‐doped Carbon Catalysts
Authors: Koshy David M. , Chen Shucheng , Lee Dong Un , Stevens Michaela Burke , Abdellah Ahmed M. , Dull Samuel M. , Chen Gan , Nordlund Dennis , Gallo Alessandro , Hahn Christopher , Higgins Drew C. , Bao Zhenan , Jaramillo Thomas F. 
Published: January 2020

AbstractNi,N‐doped carbon catalysts have shown promising catalytic performance for CO2 electroreduction (CO2R) to CO; this activity has often been attributed to the presence of nitrogen‐coordinated, single Ni atom active sites. However, experimentally confirming Ni−N bonding and correlating CO2 reduction (CO2R) activity to these species has remained a fundamental challenge. We synthesized polyacrylonitrile‐derived Ni,N‐doped carbon electrocatalysts (Ni‐PACN) with a range of pyrolysis temperatures and Ni loadings and correlated their electrochemical activity with extensive physiochemical characterization to rigorously address the origin of activity in these materials. We found that the CO2R to CO partial current density increased with increased Ni content before plateauing at 2 wt % which suggests a dispersed Ni active site. These dispersed active sites were investigated by hard and soft X‐ray spectroscopy, which revealed that pyrrolic nitrogen ligands selectively bind Ni atoms in a distorted square‐planar geometry that strongly resembles the active sites of molecular metal–porphyrin catalysts.
Iron‐Catalyzed Direct Oxidative Alkylation and Hydroxylation of Indolin‐2‐ones with Alkyl‐Substituted N‐Heteroarenes
Authors: Hu Ren‐Ming , Han Dong‐Yang , Li Ning , Huang Jie , Feng Yu , Xu Da‐Zhen 
Published: January 2020

AbstractPresented herein is the first direct alkylation and hydroxylation reaction between two different C(sp3)−H bonds, indolin‐2‐ones and alkyl‐substituted N‐heteroarenes, through an oxidative cross‐coupling reaction. The reaction is catalyzed by a simple iron salt under mild ligand‐free and base‐free conditions. The reaction is environmentally benign, employs air (molecular oxygen) as the terminal oxidant and oxygen source for the synthesis of O‐containing compounds, and produces only water as the byproduct.
The Dynamic Nature of CO Adlayers on Pt(111) Electrodes
Authors: Wei Jie , Amirbeigiarab Reihaneh , Chen Yan‐Xia , Sakong Sung , Gross Axel , Magnussen Olaf M. 
Published: January 2020

AbstractCO adlayers on Pt(111) electrode surfaces are an important electrochemical system and of great relevance to electrocatalysis. The potential‐dependent structure and dynamics of these adlayers are complex and still controversial, especially in the CO pre‐oxidation regime. We here employ in situ high‐speed scanning tunneling microscopy for studying the surface phase behavior in CO‐saturated 0.1 m H2SO4 on the millisecond time scale. At potentials near the onset of CO pre‐oxidation local fluctuations in the (2×2)‐CO adlayer are observed, which increase towards more positive potentials. Above 0.20 V (vs. Ag/AgCl), this leads to an adlayer where COad apparently reside on every top site, but still exhibit a (2×2) superstructure modulation. We interpret this observation as a dynamic effect, caused by a small number of highly mobile point defects in the (2×2)‐CO adlayer. As shown by density functional theory calculations, the CO lattice near such defects relaxes into a local (1×1) arrangement, which can rapidly propagate across the surface. This scenario, where a static (2×2) COad sublattice coexists with a highly dynamic sublattice of partially occupied top sites, explains the pronounced COad surface mobility during electrooxidation.
Aldolase Cascade Facilitated by Self‐Assembled Nanotubes from Short Peptide Amphiphiles
Authors: Reja Antara , Afrose Syed Pavel , Das Dibyendu 
Published: January 2020

AbstractEarly evolution benefited from a complex network of reactions involving multiple C−C bond forming and breaking events that were critical for primitive metabolism. Nature gradually chose highly evolved and complex enzymes such as lyases to efficiently facilitate C−C bond formation and cleavage with remarkable substrate selectivity. Reported here is a lipidated short peptide which accesses a homogenous nanotubular morphology to efficiently catalyze C−C bond cleavage and formation. This system shows morphology‐dependent catalytic rates, suggesting the formation of a binding pocket and registered enhancements in the presence of the hydrogen‐bond donor tyrosine, which is exploited by extant aldolases. These assemblies showed excellent substrate selectivity and templated the formation of a specific adduct from a pool of possible adducts. The ability to catalyze metabolically relevant cascade transformations suggests the importance of such systems in early evolution.
Photocontrolled Synthesis of n‐Type Conjugated Polymers
Authors: Woods Eliot F. , Berl Alexandra J. , Kalow Julia A. 
Published: January 2020

AbstractCurrent approaches to synthesize π‐conjugated polymers (CPs) are dominated by thermally driven, transition‐metal‐mediated reactions. Herein we show that electron‐deficient Grignard monomers readily polymerize under visible‐light irradiation at room temperature in the absence of a catalyst. The product distribution can be tuned by the wavelength of irradiation based on the absorption of the polymer. Conversion studies are consistent with an uncontrolled chain‐growth process; correspondingly, chain extension produces all‐conjugated n‐type block copolymers. Preliminary results demonstrate that the polymerization can be expanded to donor–acceptor alternating copolymers. We anticipate that this method can serve as a platform to access new architectures of n‐type CPs without the need for transition‐metal catalysis.
Solid‐phase extraction materials based on molecularly imprinted polymers for recognition of pyrethroids
Authors: Guo Ting , Zhou Hongyuan , Yu Yong , Dai Hongjie , Zhang Yuhao , Ma Liang 
Published: January 2020

ABSTRACTA novel recognition material for detection of kinds of pyrethroids was successfully synthesized by molecular imprinting technology. 3‐Phenoxybenzoic acid (PBA) usually could be the antigen to prepare the polyclonal antibody. In this work, the recognition material was prepared utilizing PBA as the template, methacrylicacid as the functional monomer and ethylene glycol dimethacrylate as the crosslinker. The recognition material was characterized by atomic force microscope, adsorption equilibrium and selectivity experiments. The results showed that the recognition material has been successfully prepared and recognized four pyrethroids (fenpropathrin, deltamethrin, fenvalerate, and cyhalothrin). The recognition material was utilized as sorbents in solid‐phase extraction for separation and detection of pyrethroids in practically samples. Under the optimal conditions, the recoveries were ranging from 74.3 to 111.0%. Therefore, novel materials for pyrethroids are very promising for future applications. © 2020 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48919.
Brain‐derived neurotrophic factor and Glial cell line‐derived neurotrophic factor expressions in the trigeminal root entry zone and trigeminal ganglion neurons of a trigeminal neuralgia rat model
Authors: Luo Daoshu , Luo Lili , Lin Ren , Lin Ling , Lin Qing 
Published: January 2020

AbstractMicrovascular compression on the trigeminal root entry zone (TREZ) is the main etiology of trigeminal neuralgia (TN) patients. To investigate brain‐derived neurotrophic factor (BDNF) and glial cell line‐derived neurotrophic factor (GDNF) in the trigeminal ganglion (TG) and TREZ, immunofluorescence staining and Western blot were used in a rat TN model. Both BDNF and GDNF were observed in the TG neurons and TREZ. The expression of the BDNF dimer in the TG was increased in the TN group, while GDNF expression was decreased after compression injury. The BDNF dimer/pro‐BDNF ratio in the TREZ of the TN group was higher than that in the sham group, but the GDNF expression in the TREZ was significantly lower than that in the sham group. These results suggested that compression injury in the TREZ of rats induced dynamic changes in BDNF and GDNF in both the TG and TREZ, and these changes are involved in the nociceptive transmission of the TN animal model.
Triclosan treatment to pregnant albino rats affects offspring numbers and the liver of both the pregnant rats and their offspring, and these effects are ameliorated by co‐treatment with bee honey
Authors: Hanafy Safaa M. , Abo‐Ouf Amany M. , Mohamed Amany F. , Arafa Mona A. A. , Shawky Lamiaa M. 
Published: January 2020

AbstractWe have assessed the effects of the broad‐spectrum bactericide triclosan on the liver of pregnant albino rats and their offspring, and evaluated the protective potential of bee honey, which has radical‐scavenging properties. The study involved treatment of 72 pregnant rats followed by examination of the pregnant rats and their offspring. The pregnant rats were divided equally into six groups (I–VI), each of which was subdivided equally into two Subgroups (A and B). Rats in the A subgroups were gavaged with a daily dose of 1.26 ml distilled water (IA), 1 ml corn oil (IIA), 1.68 ml aqueous solution of Clover Blossom honey (IIIA), 0.3 mg triclosan (IVA), 13 mg triclosan (VA), or 1.68 ml aqueous solution of honey with 13 mg triclosan (VIA), throughout pregnancy. Rats in the B subgroups received the same treatments throughout pregnancy and for 14 days after delivery. At the end of the experiments, the offspring's numbers were recorded and blood samples were taken from the pregnant rats for analysis. The livers of the studied groups were subjected for; histological study, morphometric analysis, and biochemical estimation of markers of oxidative stress. The results showed that the acceptable daily intake of triclosan did not induce significant pathological changes in the liver while high dose of triclosan induced pathological changes in the livers and reduced the numbers of offspring. Co‐administration of honey with triclosan ameliorated most pathological change. Therefore, decrease the exposure of the pregnant women to triclosan is encouraged or co‐supplementation with bee honey if exposure could not be avoided.
Emission Control by Molecular Manipulation of Double‐Paddled Binuclear PtII Complexes at the Air‐Water Interface
Authors: Adachi Junya , Mori Taizo , Inoue Ryo , Naito Masaya , Le Ngoc Ha‐Thu , Kawamorita Soichiro , Hill Jonathan P. , Naota Takeshi , Ariga Katsuhiko 
Published: January 2020

AbstractMolecular functions depend on conformations and motions of the corresponding molecular species. An air–water interface is a suitable asymmetric field for the control of molecular conformations and motions under a small applied force. In this work, double‐paddled binuclear PtII complexes containing pyrazole rings linked by alkyl spacers were synthesized and their orientations and emission properties dynamically manipulated at the air–water interface. The complexes emerge from water with concurrent variation of interface orientation of the planes of the PtII complexes from perpendicular to parallel during mechanical compression suggesting a unique ‘submarine emission‘. Phosphorescence of the complexes is quenched at the air–water interface prior to monolayer formation with intensities subsequently rapidly increasing during monolayer compression. These results indicate that asymmetric reactions and motions might be controlled by applying mechanical force at the air–water interface.
Using a Heme‐Based Nanozyme as Bifunctional Redox Mediator for Li−O2 Batteries
Authors: Mu Xiaowei , Liu Yufeng , Zhang Xueping , Wei Hui , He Ping , Zhou Haoshen 
Published: January 2020

AbstractThe realization of practical aprotic Li−O2 batteries is hindered by superoxide‐related parasitic reactions and high overpotentials. Herein, a heme‐based nanozyme containing iron‐porphyrin derivative ligands is used as a novel electrolyte additive to scavenge superoxide radicals in the Li−O2 system. Specially, this type of nanozyme can act as a bifunctional catalyst for both discharge and charge by coordinating with superoxide intermediates, functioning as a molecular shuttle of superoxide species and electrons between cathodes and products. As a consequence, the Li−O2 batteries exhibit boosted discharge capacity, reduced charge polarization and superior cycling stability in the presence of the nanozyme additive. This first attempt to using nanozyme in Li−O2 batteries should pave a new way for the sustainable cross‐link between biomimetic enzymes and advanced energy storage.