bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential expression and localization of thermosensitive Transient Receptor Potential Vanilloid (TRPV) channels in the mature sperm of white pekin duck (Anas platyrhynchos)
Authors: Majhi Rakesh Kumar , Kumar Ashutosh , Giri Sunil C. , Goswami Chandan 
Published: February 2020

AbstractSperm cells have the ability of precise chemotactic and thermotactic movement which is crucial for fertilization, yet the key molecules involved in the detection of different chemical and physical stimuli and guide the sperm cells for proper navigation are not known. This aspect is more complex as each species have their own reproductive identity. Never-the-less, Ca2+-signaling and thus a series of Ca2+-channels seem to coordinate in order to regulate different functions mediated by sperm cells. However, such aspects are controlled by different Ca2+channels and have species-specific differences. In this work we explored if TRPV channels are endogenously expressed in the mature spermatozoa obtained from avian species. We have used the sperm cells of white pekin duck (Anas platyrhynchos) as a representative avian species to explore the endogenous expression and localization of different TRPV channels. Western blot analysis (WB), flow cytometry, confocal imaging and super resolution imaging was performed for the characterization. Our results strongly suggest the expression and distinct localization of different TRPV channels in the sperm cells. All these TRPV channels are mainly absent in the head region. Only TRPV3 and TRPV4 are sparsely present in the neck region enriched with mitochondria. All these channels (TRPV1-6) are present in the tail region. The differential localization of TRPVs in duck sperm indicate their respective functions relevant in fertilization process of avian sperm. These findings may also have commercial importance in poultry production, cryopreservation of sperm as well as conservation of endangered species through artificial insemination.
Digital publishing readiness in Nigeria’s print book market
Authors: Ifeduba Emmanuel Chukwunonye 
Published: February 2020

Purpose
The purpose of this study is to examine the extent of production of digital book titles and deployment of e-promotion and how they correlate with school, library, bookshop, consumer and author readiness, with a view to enhancing publishers’ understanding of and participation in e-publishing, which is now crucial for growth and sustainability

Design/methodology/approach
A questionnaire was completed by 109 publishing firms, 79 publishing websites were observed in search of digital titles and e-promotion, and data were analysed using the SPSS to compute frequencies, percentages and correlates of digital publishing innovation adoption

Findings
It is found that 2014 digital titles (mainly textbooks and scholarly content) were issued in four formats by 33 out of 109 firms. Authors and consumers were perceived to be more digital-ready than libraries, schools and bookshops. There was a significant relationship between the issuance of digital titles and author readiness (r = 0. 372), consumer readiness (r = 0.338) and library readiness (r = 0.255). There was also a significant relationship between the adoption of e-promotion and consumer readiness (r = 0.381) and author readiness (r = 0.265).

Originality/value
Book publishing innovation research, especially in Africa, focuses mainly on the adoption of mobile devices, infrastructural challenges and reading habits, paying inadequate attention to the correlates of digital publishing adoption. The results of this study, therefore, shed light on the correlates of digital publishing adoption and should help interested publishers and scholars to understand that author, consumer and library readiness are important determinants of digital publishing adoption, especially in developing economies.
Foreigner service orientation: does the perception of other consumers matter?
Authors: Maher Amro A. , Elsharnouby Tamer H. 
Published: February 2020

Purpose
This study aims to develop and examine a model that links the foreigner service orientation, defined as indigenous consumers’ preference for service environments popular among foreign versus local consumers, to both foreigner and local comfort in intercultural service encounters.

Design/methodology/approach
The authors collected cross-sectional survey data from 516 indigenous consumers in Qatar.

Findings
According to the findings, although foreigner comfort is positively related to their service orientation, local comfort is negatively related to foreigner service orientation. The results further indicate that the relationships are intensified when cosmopolitanism or collective narcissism is high and when consumers are alone in the service setting.

Practical implications
Service firms can use the findings of this research to create a meaningful service environment based on consumers’ orientation to the in-group and out-group.

Originality value
The examination of the foreigner service orientation addresses the possibility that consumers might prefer foreign consumers to local ones in service environments. This research also addresses the dearth of research on customer-to-customer intercultural service encounter.
Collaborative and sustainable supply chain practices: a case study
Authors: Medina-Serrano Rubén , Gonzalez Reyes , Gasco Jose , Llopis Juan 
Published: February 2020

Purpose
The purpose of this paper is to explore sustainability and collaboration in supply chain (SC) management designs and to develop a sustainable supply chain design (SCD) model.

Design/methodology/approach
First, a literature review of the principal theories and SC management approaches is discussed. Second, the development of a sustainable SCD model is described and explained. Third, the results and the operationalization of the model, which incorporates sustainable procurement elements based on the results of interviews from a case study, are outlined.

Findings
A framework is proposed to provide managers, practitioners and academics with a practical solution to make sustainable SC decisions in a more structured and consistent manner.

Originality/value
The paper presents a currently discussed problem about the design of differentiated supply chains to avoid or offset the effects of allocation issues in the electronic marketplace. Although past literature reviews provide valuable results, they were based upon the assessment of supply chain decisions failing to consider the sustainable corporate social responsibility and the interaction criteria. The findings from this study highlight the importance of addressing supply chain decisions in a structured manner and prioritize the development of dynamic capabilities to improve the firm’s ability to reconfigure internal and external competences to address rapidly changing environments and reinforce a collaborative SC management system with third parties.
Global financial crisis, foreign portfolio investment and volatility
Authors: Derbali Abdelkader , Lamouchi Ali 
Published: February 2020

Purpose
The purpose of this paper is to understand and compare the extent and nature of the impact of foreign portfolio investment (FPI) on the stock market volatility, particularly in the Southeast Asian emerging markets, and compare that against the corresponding experience of Indian economy, in the context of a global financial crisis of the recent past.

Design/methodology/approach
The Asian emerging markets are now being perceived as becoming financially more and more vulnerable to international events because of their growing exposure to unstable foreign investment flows. The daily net FPI inflow and the daily leading stock market composite index of four countries, namely, Thailand, the Philippines, Indonesia and India, have been analyzed using autoregressive conditional heteroscedasticity (ARCH)-generalized ARCH group of models dividing the study period from 2000 to 2014 among pre-crisis, crisis and post-crisis period separately.

Findings
The study reveals that the net inflow of FPI has been a significant determinant of stock market returns in all countries. The impact of volatility spillover from the FPI market to the stock market in the sample countries has been found to be different under different market conditions. The past information and volatility clustering have been significantly influencing the stock market return volatilities of all these Southeast Asian countries on average.

Originality/value
However, there are significant country-wise differences in the relative importance and direction of the relationship of each of these effects with the volatility of the FPI and the stock markets. These effects have been different in these four different markets and they have significantly altered in strength and significance during the global financial crisis and in the post-financial crisis period.
The purpose of the modern corporation: a holistic view
Authors: Martin John A. , Butler Frank C. 
Published: February 2020

Purpose
This paper aims to examine the shareholder versus stakeholder debate. This paper outlines how businesses are starting to move toward a stakeholder model, and also discusses what must be done to sustain the momentum toward the stakeholder model.

Design/methodology/approach
This paper uses examples from organizations to highlight the momentum toward the stakeholder model.

Findings
This paper suggests that countervailing forces - from financial analysts, institutional investors, and institutionalized practices in many corporations - will need to be overcome if businesses are to succeed in adopting the stakeholder model.

Practical implications
Thus paper discusses the role of educators in the process of changing the mindset of students, executives, and others from a shareholder to stakeholder mindset.

Originality/value
This paper discusses not only the trend toward the stakeholder model of businesses, but also how to sustain the momentum toward this model.
Effect of flux functional group for solder paste formulation towards soldering quality of SAC305/CNT/Cu
Authors: Ismail Norliza , Jalar Azman , Abu Bakar Maria , Ismail Roslina , Saedi Ibrahim Najib 
Published: February 2020

Purpose
The purpose of this paper is to investigate the wettability and intermetallic (IMC) layer formation of Sn-3.0Ag-0.5Cu (SAC305)/CNT/Cu solder joint according to the formulation of solder paste because of different types of fluxes.

Design/methodology/approach
Solder pastes were prepared by mixing SAC305 solder powder with different flux and different wt.% of carbon nanotube (CNT). Fourier transform infrared spectroscopy was used to identify functional groups from different fluxes of as-formulated solder paste. The solder pastes were then subjected to stencil printing and reflow process. Solderability was investigated via contact angle analysis and the thickness of cross-sectionally intermetallic layer.

Findings
It was found that different functional groups from different fluxes showed different physical behaviour, indicated by contact angle value and IMC layer thickness. “Aromatic contain” functional group lowering the contact angle while non-aromatic contain functional group lowering the thickness of IMC layer. The higher the CNT wt.%, the lower the contact angle and IMC layer thickness, regardless of different fluxes. Relationship between contact angle and IMC layer thickness is found to have distinguished region because of different fluxes. Thus it may be used as guidance in flux selection for solder paste formulation.

Research limitations/implications
However, detail composition of the fluxes was not further explored for the scope of this paper.

Originality/value
The quality of solder joint of SAC305/CNT/Cu system, as indicated by contact angle and the thickness of IMC layer formation, depends on existence of functional group of the fluxes.
The development and validation of the Short Language Measure (SLaM): A brief measure of general language ability for children in their first year at school
Authors: Matov Jessica , Mensah Fiona , Cook Fallon , Reilly Sheena , Dowell Richard 
Published: February 2020

AbstractBackgroundThere is no sufficiently accurate short‐language measure that could be used by speech–language pathologists, teachers or paraprofessionals to screen young school‐aged children to identify those requiring in‐depth language evaluations. This may be due to poor development of the available measures, which have omitted crucial test development steps. Applying more stringent development procedures could result in a measure with sufficient accuracy.AimsTo create and validate a short‐language measure that has acceptable accuracy, validity and reliability, and which can be used to identify children who require further assessment and/or referral to speech–language services.Methods & ProceduresThe study consisted of two phases. In Phase 1 (measure creation), 56 children were assessed with 160 direction‐following and sentence‐recall test items and a reference measure, the Clinical Evaluation of Language Fundamentals—Fourth Edition (CELF‐4). Items were then examined for their individual characteristics (validity, reliability, difficulty and discrimination) via item analysis and the highest quality items were selected to form the Short Language Measure (SLaM). In Phase 2 (measure validation), 126 children were assessed with the SLaM and the reference measure (CELF‐4) to determine SLaM's accuracy, validity and reliability.Outcomes & ResultsA total of 40 test items were selected to form SLaM in Phase 1. Findings from Phase 2 indicated that SLaM had an accuracy of 94% (sensitivity = 94%, specificity = 93%), validity of 0.89 and reliability of 0.93. These values remained relatively consistent across both phases.Conclusions & ImplicationsThe results indicated that SLaM has excellent psychometric properties. It can be used to identify children who need further evaluation by a speech–language pathologist.What this paper addsWhat is already known on this subject

Prior research suggests that combining a direction‐following and a sentence‐recall task has sufficient discrimination accuracy and agreement with an omnibus language measure. Trialling a large set of direction‐following and sentence‐recall test items to select those with the highest individual characteristics could result in an effective short‐language measure.What this paper adds to existing knowledge

A short‐language measure (SLaM) was created and validated on two independent samples of children. Items with the highest validities, reliabilities and discrimination capacities were selected to form SLaM. This procedure resulted in a measure with high validity and reliability that exceeded the criterion for adequate discrimination accuracy.What are the potential or actual clinical implications of this work?

SLaM is an effective measure that can accurately identify children who require detailed evaluations by speech–language pathologists.
Practice Based Evidence Based Practice, part II: Navigating complexity and validity from within
Authors: van Hennik Robert 
Published: February 2020

This article describes ‘Feedback‐informed Therapy within Systems (FITS) as Practice Based Evidence Based Practice (PBEBP)’. In FITS as PBEBP practice and research effectively intertwine. The therapist is both practitioner and researcher and involves clients as co‐researchers. The output of research is input for therapy in the ‘collaborative learning community’ constituted together. Participants co‐research patterns of communication within layers of context and examine the effects of their collaboration. I will illustrate this process of systemic practice‐based research in a seven‐step research design, referring to three (anonymised) systemic therapy cases. Therapist and clients produce ‘validity from within’ when they develop explanations of experiences in stories which are accepted as coherent and generative within a community of concern.Practitioner points

Family therapists are encouraged to research their practice and involve family members as co‐researchers in order to explore their ongoing collaboration in learning how to learn

In FITS as Practice Based Evidence Based Practice research and practice are intertwined

Small spontaneous differences can make a difference that matters, and be the tipping point in the process of transformation

Practice Based Evidence Based Practice could be used as an alternative to the introduction of evidence‐based protocols
Adolescent binge‐ethanol accelerates cognitive impairment and β‐amyloid production and dysregulates endocannabinoid signaling in the hippocampus of APP/PSE mice
Authors: Ledesma Juan Carlos , Rodríguez‐Arias Marta , Gavito Ana L. , Sánchez‐Pérez Ana M. , Viña José , Medina Vera Dina , Rodríguez de Fonseca Fernando , Miñarro José 
Published: February 2020

AbstractPrevious research in rodents suggests that the long‐term neurobehavioral disturbances induced by chronic ethanol (EtOH) exposure could be due to endocannabinoid system (ECS) alterations. Moreover, ECS failure has been proposed to mediate the cognitive impairment and β‐amyloid production in Alzheimer disease (AD). Thus, in the present study, we evaluated the effects of adolescent EtOH binge drinking on the cognitive disturbances, hippocampal β‐amyloid levels, and in the ECS expression on a transgenic mouse model (APP/PSEN, AZ) of AD. We exposed AZ and wild‐type mice to a binge‐drinking treatment during adolescence. At 6 and 12 months of age, we evaluated hippocampal‐dependent learning and memory: β‐amyloid concentrations and RNA and protein levels of cannabinoid type‐2 receptors (CB2), diacylglycerol lipase‐α (DAGLα), and monoacylglycerol lipase (MAGL) in the hippocampus. The results showed that binge‐EtOH treatment worsens cognitive function and increases β‐amyloid levels in AZ. At 6 months, EtOH heightens CB2 (RNA and protein) and DAGLα (RNA) expression in wild type but not in AZ. On the contrary, EtOH enhances MAGL RNA expression only in AZ. At 12 months, AZ displays increased levels of CB2 (RNA and protein) and DAGLα (protein) compared with control. Similar to what happens at 6 months, EtOH induces an increase in CB2 gene expression in wild type but not in AZ; however, it augments CB2 and DAGLα protein levels in both genotypes. Therefore, we propose that adolescent binge drinking accelerates cognitive deficits associated with aging and AD. It also accelerates hippocampal β‐amyloid accumulation in AZ and affects differently the ECS response in wild type and AZ.
Decreased retinal thickness in preschool offspring of maternal gestational hypertension: the Nanjing Eye Study
Authors: Zhao Xiaoyan , Li Rui , Huang Dan , Tong Haohai , Zhu Hui , Wang Yue , Zhang Xiaohan , Hao Qingfeng , Sun Qigang , Liu Hu 
Published: February 2020

AbstractPurposeTo evaluate the influence of maternal gestational hypertension (GH) on retinal thickness of 5–6‐year‐old children, including macular thickness, ganglion cell‐inner plexiform layer (GC‐IPL) thickness and peripapillary retinal nerve fibre layer (RNFL) thickness.MethodsAs part of Nanjing Eye Study, comprehensive ocular examinations were conducted in children aged 61–72 months, including noncycloplegic refraction, ocular biometric parameters and retinal parameters. Retinal thickness was measured by Spectral Domain‐Optical Coherence Tomography. Data on pregnancy and birth history were obtained from a detailed questionnaire completed by parents.ResultsAmong 1062 children [mean age (standard deviation): 66.9 (3.4) months] with complete from eye examination and questionnaire, 30 (2.8%) children were born with maternal GH. In generalized linear models (adjusted for sex, age, spherical equivalent, axial length, body mass index, birth weight and premature history), children born with maternal GH had thinner average RNFL thickness (100.5 versus 104.4 μm, p = 0.035), superior RNFL thickness (123.7 versus 132.0 μm, p = 0.007), superior GC‐IPL thickness (83.7 versus 86.4 μm, p = 0.005), superior‐nasal GC‐IPL thickness (86.3 versus 88.4 μm, p = 0.029) and superior outer macular thickness (278.0 versus 283.0 μm, p = 0.034) than children born with normal pregnancy.ConclusionChildren exposed to maternal GH tended to have thinner macular, RNFL and GC‐IPL thickness. These findings suggest that maternal GH may affect the development of retina in children thus hinders the development of the offspring's nervous system.
Tear and aqueous humour cytokine profile in primary open‐angle glaucoma
Authors: Burgos‐Blasco Barbara , Vidal‐Villegas Beatriz , Saenz‐Frances Federico , Morales‐Fernandez Laura , Perucho‐Gonzalez Lucia , Garcia‐Feijoo Julian , Martinez‐de‐la‐Casa Jose M 
Published: February 2020

AbstractPurposeTo evaluate the concentrations of pro‐inflammatory cytokines in tear and aqueous humour of patients with primary open‐angle glaucoma (POAG), relative to healthy controls.MethodTear and aqueous humour samples were collected from 29 healthy controls and 27 POAG patients. Twenty‐seven inflammatory cytokines were analysed: interleukin (IL)‐1β, IL‐1ra, IL‐2, IL‐4, IL‐5, IL‐6, IL‐7, IL‐8, IL9, IL‐10, IL‐12, IL‐13, IL‐15, IL‐17, eotaxin, fibroblast growth factor (FGF) basic, granulocyte colony‐stimulating factor, granulocyte‐monocyte colony‐stimulating factor, interferon (IFN)‐γ, interferon gamma‐induced protein, monocyte chemo‐attractant protein‐1, macrophage inflammatory protein (MIP)‐1α, MIP‐1β, platelet‐derived growth factor, regulated on activation normal T cell expressed and secreted, tumour necrosis factor (TNF)‐α and vascular endothelial growth factor (VEGF).ResultsIn tear samples of glaucoma patients, an increase in IL‐4, IL‐12, IL‐15, FGF‐basic and VEGF was observed, as well as a decrease in MIP‐1a relative to the control group (p < 0.05). IL‐5, IL‐12, IL‐15, IFN‐γ and MIP‐1a were significantly higher in aqueous humour of glaucoma eyes (p < 0.05). A poor correlation between cytokine levels in tear and aqueous humour was observed.ConclusionThe different profiles of inflammatory marker expression of patients with POAG and healthy controls confirm the inflammatory activity of the pathology, indicating that some of them could be used as potential biomarkers of this disease.
Late onset oxygen requirement following neonatal therapeutic hypothermia
Authors: El‐Dib Mohamed , Munster Chelsea , Szakmar Eniko , Inder Terrie , Gunn Alistair J. 
Published: February 2020

AbstractAimTo investigate the characteristics of infants with neonatal encephalopathy (NE) receiving therapeutic hypothermia (TH) who developed late onset oxygen requirement during or after rewarming.MethodsInfants were stratified by receiving (a) new onset isolated oxygen requirements during or after rewarming; (b) no respiratory support during hospital stay; and (c) invasive and/or non‐invasive respiratory support before or during cooling.ResultsOf 136 infants treated with TH, 49 (36%) did not require any respiratory support, and 78 (57.4%) received invasive or non‐invasive support before or during cooling. Nine infants (6.6%) developed late onset oxygen requirement. The late onset oxygen requirement started at median age of 3.8 days (IQR 3.6‐5.2) and ended at median 7.5 days (IQR 5.8‐12.7). Total hours of O2 exposure were median 62.0 (IQR 24.4‐112.6). Maximum support was low‐flow nasal cannula from 100% oxygen source with a flow rate of 40‐250 mL/min. Infants in this group had higher Apgar scores, milder metabolic acidosis and no seizures. Three infants had diagnostic investigations without significant findings.ConclusionA small percentage of neonates with NE developed late onset oxygen requirement during or after rewarming. Late oxygen requirement was associated with evidence of less severe perinatal hypoxia‐ischaemia.