bluuebunny/crossref_metadata_2025_split huggingface dataset:
Química mineral e condições de cristalização (P-T-ƒO2) do Plúton Maravilha, Domínio PEAL (Província Borborema)
Authors: Dáttoli Luan Cavalcante , Silva Filho Adejardo Francisco da , Guimarães Ignez De Pinho , Lima Jefferson Valdemiro de , Garcia Pedro Maciel de Paula , Arouca Júnior Ramon Matos , Bonfim Pedro Henrique Silveira Lélis , Santiago Renato Carlos Vieira 
Published: October 2019

O Plúton Maravilha, localizado no Domínio Pernambuco-Alagoas, tem dimensão de aproximadamente 200 km2, alongado em direção WSW-ENE. Apresenta composição modal tonalítica, textura fanerítica inequigranular, por vezes porfirítica, com quantidades variáveis de plagioclásio, biotita, anfibólio e quartzo, por vezes microclínio, presença de epídoto magmático, tendo como principais fases acessórias titanita, apatita, zircão e allanita. Neste trabalho foram analisadas as principais fases minerais presentes no plúton, visando a compreender sua evolução petrogenética e condições de cristalização. Em porções mais deformadas, o plúton apresenta-se fortemente foliado, marcado pela presença de biotitas primárias, em vasta maioria, cloritizadas nas bordas, podendo ser produto de hidrotermalismo ou de estágios iniciais de reações metamórficas, sendo classificadas entre a solução sólida eastonita-siderofilita. Os anfibólios são predominantemente magmáticos, classificados em grande maioria como pargasita e ferro-pargasita. Cálculos geobarométricos mostram valores de 6 a 7,18 kbar, enquanto a geotermometria foi estimada entre 706 e 785ºC, utilizando o conteúdo de AlIV em plagioclásios e anfibólios em equilíbrio. A presença da assembleia magnetita+titanita+quartzo em equilíbrio, os valores de Fe# na biotita e anfibólios, assim como cristais de magnetita euédricos a subédricos associados à titanita euédrica losangular como fases precoces, indicam que o magma progenitor era relativamente oxidado.
Análise tectonossedimentar das fases início de rifte e clímax de rifte da Bacia do Araripe, Nordeste do Brasil
Authors: Fambrini Gelson Luís , Silva-Filho Wellington Ferreira da , Lemos Diógenes Ribeiro de , Silvestre Diego Da Cunha , Araújo Jadson Trajano de , Menezes-Filho José Acioli Bezerra de , Tesser Junior Sidney , Neumann Virginio Henrique De Miranda Lopes 
Published: October 2019

Este trabalho objetivou a caracterização tectonossedimentar das fases início de rifte e clímax de rifte da Bacia do Araripe. As principais estruturas identificadas foram falhas normais, transcorrentes e inversas em ordem de importância. Esse grupo de falhas coloca lateralmente diferentes unidades litoestratigráficas como rochas de unidades início de rifte e clímax de rifte. Exemplo é o contato lateral das formações Missão Velho e Brejo Santo ao longo de falhas normais NNE. É de grande importância a integração entre análise geométrica e cinemática dessas falhas com a evolução estratigráfica para uma evolução global da evolução geológica da Bacia do Araripe. Principais afloramentos de campo utilizados neste trabalho consistem em exposições formadas durante as obras de construção da ferrovia Transnordestina e da transposição do Rio São Francisco. A análise tectônica realizada para este trabalho identificou dois conjuntos principais de falhas: falhas orientadas segundo a direção NE-SW (mais antigas) e falhas orientadas na direção NW-SE e WNW-ESE (mais jovens). Além disso, foram também analisadas falhas transcorrentes e inversas. A tectônica rifte que afetou a Bacia do Araripe (extensional) reativou falhas antigas do embasamento Pré-Cambriano e, por sua vez, forneceu falhas normais de direção NE-SW e também gerou falhas de orientação E-W e NW-SE.
Comparisons of Rivaroxaban Following Different Dosage Criteria (ROCKET AF or J‐ROCKET AF Trials) in Asian Patients With Atrial Fibrillation
Authors: Chan Yi‐Hsin , Lee Hsin‐Fu , Wang Chun‐Li , Chang Shang‐Hung , Yeh Chih‐Hsin , Chao Tze‐Fan , Yeh Yung‐Hsin , Chen Shih‐Ann , Kuo Chi‐Tai 
Published: October 2019

Background

The
ROCKET AF
(Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) evaluated rivaroxaban (20/15 mg/d) versus warfarin in patients with atrial fibrillation. A separate trial, J‐
ROCKET
AF (Japanese ROCKET AF), compared rivaroxaban (15/10 mg/d) and warfarin in Japanese patients with atrial fibrillation. Data about rivaroxaban following J‐
ROCKET AF
criteria compared with warfarin and
ROCKET AF
dosage were limited.

Methods and Results

This retrospective study used medical data from a multicenter healthcare provider in Taiwan that included 3162 patients taking rivaroxaban. Among 2320 patients with an estimated glomerular filtration rate (
eGFR
) ≥50 mL/min per 1.73 m
2
, 384 and 1936 patients followed the
ROCKET AF
(20 mg/d) and J‐
ROCKET AF
(15 mg/d) recommendation, respectively. Among 842 patients with an
eGFR
<50 mL/min per 1.73 m
2
, 422 and 420 patients followed the
ROCKET AF
(15 mg/d) and J‐
ROCKET AF
(10 mg/d) recommendation, respectively. A total of 2053 patients with atrial fibrillation receiving warfarin were identified. Rivaroxaban following either
ROCKET AF
or J‐
ROCKET AF
dosage criteria was associated with a comparable risk of thromboembolism but a lower risk of bleeding than warfarin. For patients with an
eGFR
≥50 mL/min per 1.73 m
2
, risks of clinical events did not differ significantly between the 2 dosage criteria of rivaroxaban. For patients with an
eGFR
<50 mL/min per 1.73 m
2
, the
ROCKET AF
dosage was associated with a higher risk of major bleeding compared with the J‐
ROCKET AF
dosage (hazard ratio, 2.70;
P
=0.0445) without significant differences regarding the risk of ischemic events.

Conclusions

In Asian patients with atrial fibrillation, the J‐
ROCKET AF
dosage was as effective as the
ROCKET AF
dosage irrespective of renal function. The risk of major bleeding was lower with the J‐
ROCKET AF
dosage in patients with an
eGFR
<50 mL/min per 1.73 m
2
. Compared with warfarin, rivaroxaban following either dosage criteria was effective and even safer.
CTRP9 Ameliorates Atrial Inflammation, Fibrosis, and Vulnerability to Atrial Fibrillation in Post‐Myocardial Infarction Rats
Authors: Liu Mingxin , Li Wei , Wang Huibo , Yin Lin , Ye Bingjie , Tang Yanhong , Huang Congxin 
Published: October 2019

Background

Inflammation and fibrosis play an important role in the pathogenesis of atrial fibrillation (
AF
) after myocardial infarction (
MI
). CTRP9 (C1q/tumor necrosis factor‐related protein‐9) as a secreted glycoprotein can reverse left ventricle remodeling post‐
MI
, but its effects on
MI
‐induced atrial inflammation, fibrosis, and associated
AF
are unknown.

Methods and Results

MI
model rats received adenoviral supplementation of
CTRP
9 (Ad‐
CTRP
9) by jugular‐vein injection. Cardiac function, inflammatory, and fibrotic indexes and related signaling pathways, electrophysiological properties, and
AF
inducibility of atria in vivo and ex vivo were detected in 3 or 7 days after
MI
. shCTRP9 (short hairpin CTRP9) and sh
RNA
were injected into rat and performed similar detection at day 5 or 10. Adverse atrial inflammation and fibrosis, cardiac dysfunction were induced in both
MI
and Ad‐GFP (adenovirus‐encoding green fluorescent protein)+
MI
rats. Systemic
CTRP
9 treatment improved cardiac dysfunction post‐
MI
.
CTRP
9 markedly ameliorated macrophage infiltration and attenuated the inflammatory responses by downregulating interleukin‐1β and interleukin‐6, and upregulating interleukin‐10, in 3 days post‐
MI
; depressed left atrial fibrosis by decreasing the expressions of collagen types I and
III
, α‐
SMA
, and transforming growth factor β1 in 7 days post‐
MI
possibly through depressing the Toll‐like receptor 4/nuclear factor‐κB and Smad2/3 signaling pathways. Electrophysiologic recordings showed that increased
AF
inducibility and duration, and prolongation of interatrial conduction time induced by
MI
were attenuated by
CTRP
9; moreover,
CTRP
9 was negatively correlated with interleukin‐1β and
AF
duration. Downregulation of
CTRP
9 aggravated atrial inflammation, fibrosis, susceptibility of
AF
and prolonged interatrial conduction time, without affecting cardiac function.

Conclusions

CTRP
9 is effective at attenuating atrial inflammation and fibrosis, possibly via its inhibitory effects on the Toll‐like receptor 4/nuclear factor‐κB and Smad2/3 signaling pathways, and may be an original upstream therapy for
AF
in early phase of
MI
.
Mitochondrial lineages or discrete species? Assessing diversity within Timon tangitanus (Lacertidae) using mitochondrial and nuclear DNA sequences
Authors: Abreu João M. , Salvi Daniele , Perera Ana , Harris D. James 
Published: October 2019

Abstract
Identification of extremely high levels of mitochondrial DNA (mtDNA) sequence divergence within reptiles from North Africa is commonplace. This high divergence often compares with interspecific levels among widely accepted species, leading to the hypothesis of the occurrence of species complexes. Indeed, in many examples, data from nuclear markers support such taxonomic recognition. Such is the case of two recently recognized ocellated lizard species of the genus Timon, T. nevadensis, from Spain, and T. kurdistanicus, from the Middle East, which both showed notable genetic differentiation from their sister taxa. In North Africa, highly divergent mtDNA lineages of Timon tangitanus were previously identified but not corroborated with nuclear markers. Here we expand geographic sampling across the range of Timon tangitanus and complement mtDNA sequences with data from nuclear markers (MC1R and ACM4). We identify four divergent mtDNA lineages, at a level similar to some reptile species. However, the nuclear markers show limited differentiation and lack of lineage sorting. This and some other recent assessments within reptiles discourage the use of mtDNA data alone as a proxy for taxonomic units, demonstrating once more the need for integrative taxonomic approaches.
Prophecy in Roman Judaea: Did Josephus Report the Failure of an ‘Exact Succession of the Prophets’ (Against Apion 1.41)?
Authors: Mason Steve 
Published: October 2019

AbstractIn Ag. Ap. 1.41, after stressing that the Jewish holy books are rightly trusted because only prophets wrote them, Josephus remarks that Judaeans do not trust later writings in the same way. The reason he gives is usually translated as “the failure of the exact succession of the prophets.” Whereas older scholarship played down this reason to insist on the absence of prophecy in post-biblical Judaism, the prevailing view today holds that Josephus meant only to qualify later prophecy, not to exclude it. This essay broaches the more basic question of what an ἀκριβὴς διαδοχή means. Arguing that an exact diachronic succession of prophets makes little sense, it offers two proposals that better suit Josephus’ argument. It further contends that Josephus is talking about the ancient Judaean past, the subject of this work, not about the work of later historians including himself. He distinguishes sharply between prophecy and historical inquiry.
Global Trends of Sea Surface Gravity Wave, Wind, and Coastal Wave Setup
Authors: Lin Yuchun , Oey Leo 
Published: October 2019

AbstractAssessing trends of sea surface wave, wind, and coastal wave setup is of considerable scientific and practical importance in view of recent and projected long-term sea level rise due to global warming. Here we analyze global significant wave height (SWH) and wind data from 1993 to 2015 and a wave model to (i) calculate wave age and explain the causal, or the lack thereof, relationship between wave and wind trends; and (ii) estimate trends of coastal wave setup and its contributions to secular trends of relative sea level at coastal locations around the world. We show in-phase, increasing SWH and wind trends in regions dominated by younger waves, and decreasing SWH trends where older waves dominate and are unrelated to the local wind trends. In the central North Pacific where wave age is transitional, in-phase decreasing wave and wind trends are found over the west-northwestern region, but wave and wind trends are insignificantly correlated in the south-southeastern region; here, a reversed, upward momentum flux from wave to wind is postulated. We show that coastal wave setup depends primarily on open-ocean SWH but only weakly on wind, varying approximately like SWH/(wind speed)1/5. The wave-setup trends are shown to be increasing along many coastlines where the local relative sea level trends are also increasing: the North and Irish Seas, Mediterranean Sea, East and South Asian seas, and eastern United States, exacerbating the potential for increased floods along these populated coastlines.
Subseasonal Forecast Skill over the Northern Polar Region in Boreal Winter
Authors: Lin Hai 
Published: October 2019

AbstractPentad (5-day averaged) forecast skill over the Arctic region in boreal winter is evaluated for the subseasonal to seasonal prediction (S2S) systems from three operational centers: the European Centre for Medium-Range Weather Forecasts (ECMWF), the U.S. National Centers for Environmental Prediction (NCEP), and Environment and Climate Change Canada (ECCC). The results indicate that for a lead time longer than about 10 days the forecast skill of 2-m air temperature and 500-hPa geopotential height in the Arctic area is low compared to the tropical and midlatitude regions. The three S2S systems have comparable forecast skill in the northern polar region. Relatively high skill is observed in the Arctic sector north of the Bering Strait in pentads 4–6. Possible sources of S2S predictability in the polar region are explored. The polar forecast skill is found to be dependent on the phase of the Arctic Oscillation (AO) in the initial condition; that is, forecasts initialized with the negative AO are more skillful than those starting from the positive AO. This is likely due to the influence of the stratospheric polar vortex. The tropical MJO is found to also influence the prediction skill in the polar region. Forecasts starting from MJO phases 6–7, which correspond to suppressed convection in the equatorial eastern Indian Ocean and enhanced convection in the tropical western Pacific, tend to be more skillful than those initialized from other MJO phases. To improve the polar prediction on the subseasonal time scale, it is important to have a well-represented stratosphere and tropical MJO and their associated teleconnections in the model.
Vitamin D Levels in Children With Recurrent Aphthous Stomatitis
Authors: Nalbantoğlu Burçin , Nalbantoğlu Ayşin 
Published: October 2019

Background: Recurrent aphthous stomatitis is one of the most prevalent oral mucosa diseases and the etiology is unclear. As a potent anti-inflammatory and immunomodulating agent, vitamin D can significantly affect oral cavity homeostasis. However, to the best of our knowledge, no study has been conducted in pediatric population on the potential role of vitamin D in recurrent aphthous stomatitis to date. The aim of the present study is to determine the vitamin D status in recurrent aphthous stomatitis in children. Methods: This study is conducted retrospectively. Seventy-two patients with minor recurrent aphthous stomatitis and 70 age-matched healthy controls included in the study. 25-Hydroxyvitamin D levels were measured in all patients using enzyme immunoassay. Results: Serum vitamin D levels were 16.4 (8.6) ng/mL in patient group and 23.1 (11.5) ng/mL in healthy controls. There was a statistically significant difference between the groups in terms of serum vitamin D levels ( P = .002). There was no significant correlation between serum vitamin D levels and the severity of the recurrent aphthous stomatitis ( r = 0.54, P = .76). Conclusions: Our study showed a significant difference in vitamin D levels between patients with recurrent aphthous stomatitis and the healthy control group. We also found no correlation between vitamin D status and the severity of the disease.
‘INSIGHT-PRECISION’: a new, mini-invasive technique for the surgical treatment of carpal tunnel syndrome
Authors: Carmo José Dinis 
Published: October 2019

Objective To describe a new mini-invasive surgical technique for carpal tunnel release and to present clinical findings associated with using this technique. Methods Patients with idiopathic carpal tunnel syndrome without prior surgical treatment, who underwent a new minimally-invasive surgical technique using a specific surgical tool-kit developed by the author, were included. Prospective data were collected, including preoperative electrodiagnostic testing. The subjective condition of all patients was evaluated pre- and postoperatively with a five-level Likert-type scale (LS) and muscular strength was tested using a JAMAR dynamometer and pinch gauge. Results A total of 116 patients (157 hands/cases) underwent surgery performed by the author, and were followed for a mean of 40 months (range, 6 months–7 years). Of these, preoperative electrodiagnostic testing was performed in 112 patients (96.6%). No significant complications were reported. By three months, patients reported that they were satisfied or very satisfied in 147/149 cases (98.7%; LS grade I and II). Strength recovery at three months, based on the average of four measures, was 99.17% (range, 97.43–100.97%). Conclusions The described technique is minimally invasive, safe and simple to perform, and provides good results.
Observation of the clinical efficacy of dexmedetomidine in flexible bronchoscopy under general anesthesia: clinical case experience exchange
Authors: Li Hongtu , Zhang Na , Zhang Ke , Wei Yanhua 
Published: October 2019

Object To investigate the clinical efficacy and safety of dexmedetomidine in flexible bronchoscopy under general anesthesia. Methods A total of 114 patients were randomly divided into intervention group A and control group B. Group A received dexmedetomidine, fentanyl, and propofol as anesthesia, while Group B received fentanyl and propofol only. Changes in heart rate, mean arterial pressure, pulse oxygen saturation, stress indices (blood cortisol, adrenaline, and norepinephrine levels), incidence of adverse events, anesthesia dose, duration of procedure, and recovery time were compared between the groups at specific time points T0, T1, and T2 during bronchoscopy. Results There was no statistical difference between the groups at T0. At T1 and T2, pulse oxygen saturation, mean arterial pressure, heart rate, and stress indices in group A were significantly more favorable than those in group B. The incidence of adverse events (5.26%) in group A was significantly lower than that in group B (17.54%), and patients in group A required less propofol and had a faster recovery time than patients in group B. Conclusion Dexmedetomidine use in flexible bronchoscopy under general anesthesia is safe and effective and decreases the stress response in synergy with propofol to provide hemodynamic stability.
Anesthesia in a patient with Charcot-Marie-Tooth disease with pneumothorax: a case report
Authors: Kim Jae Won , Kim Goo , Kim Tae Woo , Han Woong , Maeng Jin Hyun , Jeong Chang Young , Choi Jin Ho , Park Dong Ho 
Published: October 2019

A 21-year-old man underwent wedge resection for treatment of pneumothorax. This patient had been diagnosed with Charcot-Marie-Tooth disease (CMTD) and had a history of surgical treatment of scoliosis, pneumothorax, foot deformity, and arm dislocation. Additionally, the patient showed signs of muscle weakness and atrophy in the upper and lower extremities. CMTD is genetically associated with motor and sensory neuropathy and reportedly has an association with malignant hyperthermia or a delayed muscle relaxation mechanism. In the present case, total intravenous anesthesia was performed with a combination of propofol and remifentanil, and rocuronium was administered as a neuromuscular blocking agent. Surgery was performed without delayed muscle relaxation or any other specific intraoperative adverse events.
Outcomes After Arthroscopic Hip Labral Reconstruction: A Systematic Review and Meta-analysis
Authors: Rahl Michael D. , LaPorte Collin , Steinl Gabrielle K. , O’Connor Michaela , Lynch T. Sean , Menge Travis J. 
Published: October 2019

Background: The acetabular labrum is critical to maintenance of hip stability and has been found to play a key role in preservation of the hip fluid seal. For irreparable labral damage, arthroscopic labral reconstruction is an evolving technique that has been shown to decrease hip pain and restore function. Purpose: To provide a comprehensive review of current literature for arthroscopic hip labral reconstruction, with a focus on determining if outcomes differ between autograft or allograft tissue. Study Design: Systematic review and meta-analysis. Methods: PubMed and Scopus online databases were searched with the key terms “hip,”“labrum,”“reconstruction,” and “graft” in varying combinations. Procedures performed, complications, failures, and functional outcome measures were included in this analysis. The inverse variance method was used to calculate pooled estimates and 95% CIs. Results: Eight studies with 537 hips were included. Mean age was 37.4 years (95% CI, 34.5-40.4 years), and mean follow-up time was 29 months (95% CI, 26-33 months). Survivorship after autograft reconstruction ranged from 75.7% to 100%, as compared with 86.3% to 90.0% in the allograft cohort. In the autograft cohort, failures included 0% to 13.2% conversion to total hip arthroplasty and 0% to 11.0% revision hip arthroscopy. Failures in the allograft cohort included 0% to 12.9% total hip arthroplasty conversion, 0% to 10.0% revision arthroscopy, and 0% to 0.8% open revision surgery. Based on 6 studies, the modified Harris Hip Score improved by a mean 29.0 points after labral reconstruction ( P < .0001). Conclusion: Arthroscopic hip labral reconstruction results in clinically significant improvements in patient-reported outcomes. Our analysis indicates that there are no significant differences in outcomes based on graft type alone. A number of factors may determine graft choice, including patient preference, surgeon experience, operative time, morbidity, and cost. Proper patient selection based on age and severity of degenerative joint disease will also optimize outcomes after labral reconstruction.