bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Large Morganucodontan Mammaliaform from the Late Jurassic of Germany
Authors: Martin Thomas , Averianov Alexander O. , Jäger Kai R. K. , Schwermann Achim H. , Wings Oliver 
Published: January 2020

Abstract
An upper “triconodont” molar from the Late Jurassic (late Kimmeridgian) of the Langenberg Quarry in northern Germany is attributed to Storchodon cingulatus gen. et sp. nov. of Morganucodonta. The molar is characterized by continuous lingual and buccal cingula, and a relatively large, buccally-shifted cusp D which is not integrated in the buccal cingulum. With a length of 3.07 mm, the tooth is less than 10 % smaller than the lower holotype molar of Paceyodon davidi, the largest known morganucodontan. The Langenberg morganucodontan possibly represents an example of insular gigantism on an adjacent paleoisland.
Budget Impact of Intravenous Iron Therapy with Ferric Carboxymaltose in Patients with Chronic Heart Failure and Iron Deficiency in Romania
Authors: Lorenzovici László , Székely Andrea , Farkas-Ráduly Szabolcs , Jitaru Ciprian , Csanádi Marcell 
Published: January 2020

Abstract

Background: Ferric carboxymaltose (FCM) treatment in case of iron deficient (ID) patients with chronic heart failure (CHF) has shown great promise according to the findings of recent studies in improvement of symptoms and quality of life, New York Heart Association (NYHA) classification, and exercise capacity.

Aim of the study: The purpose of the current study is to assess the budget impact of treating CHF patients with FCM in a sample of Romanian hospitals.

Material and methods: Calculations have been based on the budget impact model developed by Theidel et al. The assumptions and clinical outcomes of the current study were based on a multivariate statistical approach used in the same German study. The predicted outcomes were based on data pooled from four double-blind randomized controlled trials. The time horizon of the model was 1 year. Budget impact calculations were performed from the public payer perspective. Two scenarios have been handled: one without applying the Clawback tax and one with applying the tax to the cost of medication.

Results: The yearly budget impact of FCM vs. no iron-replacement treatment without applying the tax ranged between €678,383 and €641,588 for 1,000 patients, resulting in €37 of additional costs per patient per year. The yearly budget impact of FCM vs. no iron-replacement treatment with applying the tax ranged between €616,934 and €641,588 for 1,000 patients, resulting in €9 of cost reduction per patient per year. Key cost drivers included the cost of outpatient visits and the cost of hospitalization due to HF worsening. Sensitivity analysis for both scenarios proved the robustness of the results.

Conclusions: The FCM treatment of CHF patients has a moderate budget impact. Moreover, this budget impact/saving translates into a reduction of the rate and length of hospitalization stay and a better symptomatic profile of the patients.
Predictors for In-hospital Mortality in Pediatric Patients with Acute Myocarditis – a Retrospective Study
Authors: Toma Daniela , Gozar Liliana , Șuteu Carmen Corina , Făgărășan Amalia , Togănel Rodica 
Published: January 2020

Abstract

Background: Acute myocarditis, a primary inflammatory cardiac disease commonly caused by viral infection, is an important cause of morbidity and mortality in children. Data obtained from forensic studies found an incidence of 15–33% for acute myocarditis in sudden deaths in the pediatric age group. Currently, there is a lack of data regarding the incidence and factors associated with short-term outcomes in pediatric patients admitted for acute myocarditis.
The aim of the study was to identify predictors for in-hospital mortality in a pediatric population admitted with acute myocarditis.

Material and methods: We conducted a retrospective observational cohort study that included 21 patients admitted for acute myocarditis. Clinical, laboratory, ECG, and imaging data acquired via 2D transthoracic echocardiography and cardiac magnetic resonance imaging were collected from the medical charts of each included patient. The primary end-point of the study was all-cause mortality occurring during hospitalization (period ranging from 10 to 14 days). The study population was divided into 2 groups according to the occurrence of the primary end-point.

Results: The mean age of the study population was 99.62 ± 77.25 months, and 61.90% (n = 13) of the patients were males. The in-hospital mortality rate was 23.9% (n = 5). Patients in the deceased group were significantly younger than the survivors (55.60 ± 56.18 months vs. 113.4 ± 78.50 months, p = 0.039). Patients that had deceased presented a significantly higher level of LDH (365 ± 21.38 U/L vs. 234.4 ± 63.30 U/L, p = 0.0002) and a significantly higher rate of ventricular extrasystolic dysrhythmias (60% vs. 6.25%, p = 0.02, OR: 22.5, 95% CI: 1.5–335) compared to survivors. The 2D echocardiography showed that patients that had deceased presented more frequently an impaired left ventricular ejection fraction (<30%) (p = 0.001) and a significantly higher rate of severe mitral regurgitation (p = 0.001) compared to survivors.

Conclusions: The most powerful predictors for in-hospital mortality in pediatric patients admitted for acute myocarditis were the presence of ventricular extrasystolic dysrhythmias on the 24h Holter ECG monitoring, impaired left ventricular systolic function (LVEF <30%), the presence of severe mitral regurgitation, and confirmed infection with Mycoplasma pneumoniae.
Radiocarbon dating of groundwater from a PZ-2 piezometer located in the foreground of Wieliczka Salt Mine, Poland
Authors: Duliński Marek , Gorczyca Zbigniew , Marzec Michał , Czub Robert , Brudnik Krzysztof 
Published: January 2020

Abstract
A comparison of two methods of radiocarbon age determination of groundwater is presented. The simplest Pearson model and the “user-defined” option of the NETPATH program were considered. Both methods were used to determine the age of water from a PZ-2 piezometer that is situated in the foreground of chamber Z-32 in Wieliczka Salt Mine. Results of these calculations clearly demonstrate that 14C ages obtained by the Pearson model can be significantly overestimated in comparison with those determined by the NETPATH code. Without additional data, such as the stable isotope composition of the water, conclusions on the age of the groundwater based solely on the Pearson model may be highly inadequate.
Dynamics of the status of groundwater in the Polish Lowland: the River Gwda catchment example
Authors: Jamorska Izabela , Kubiak-Wójcicka Katarzyna , Krawiec Arkadiusz 
Published: January 2020

Abstract
The aim of the present study is to monitor changes in the location of the groundwater table in the catchment area of the River Gwda within the Quaternary and Neogene water-bearing level over a 35-year period, between 1981 and 2015. In addition, on account of very diverse total annual precipitation levels in particular parts of the catchment, attempts were made to determine the influence of precipitation on the location of the groundwater table. By correlating groundwater level and meteorological parameters (precipitation), it was discovered that precipitation in the previous year made the largest impact on the groundwater table. Moreover, low precipitation totals in the southern part of the catchment are not discernible in groundwater table fluctuations, which is linked to the location of the observation well within the drainage zone as well as to water ascension from deeper aquifers.
The δ18O and δD isoscapes of recent groundwater in Poland
Authors: Leśniak Paweł M. , Wilamowski Andrzej 
Published: January 2020

Abstract
Considering the country’s development and quality of life, recognition of the water cycle mechanism is of great importance. A significant contribution to this comes from the isotopic composition of particular elements of the water cycle. However, a weak point is that in Poland only one element of the water cycle, precipitation, is sampled and measured over more than 312 thousands km2 at a single station. It is therefore necessary to seek extension of or alternatives for these rare data. Such an alternative is the sampling of groundwater containing tritium in the national monitoring network of groundwater bodies that is maintained by the Polish Geological Institute. Based on such data we have constructed δ18O and δD isoscapes (i.e., maps of δ18O and δD values) of recent groundwater. These data provide spatial distribution of δ18O and δD values which can be used as input to hydrogeological models.
Laboratory investigations of diclofenac migration in saturated porous media – a case study
Authors: Okońska Monika , Marciniak Marek , Zembrzuska Joanna , Kaczmarek Mariusz 
Published: January 2020

Abstract
At present, concentrations of pharmaceuticals in surface and ground waters are low; however, even low concentrations of certain substances may prove very harmful. One of such pharmaceutical drugs is diclofenac, a popular non-steroidal anti-inflammatory drug (NSAID). For this reason, it is important to determine its mobility in groundwater and to estimate parameters of migration. Authors conducted column tests for two porous media: an artificial one, consisting of glass granules, and a natural one, i.e., sandur sand obtained from a site north of the city of Poznań (Poland). During the test, impulse breakthrough curves of chloride ions and diclofenac were recorded. The results were used to identify a specific sorption model and to determine values of migration parameters. Solutions of the inverse problem using optimisation methods and of equations of mathematical migration models were carried out in a MATLAB environment. Based on test results, the mobility of diclofenac is shown to be very high and comparable to that of chloride ions. The tests also revealed a slight and irreversible sorption of diclofenac on grains of both porous media.
Identification of transport parameters of chlorides in different soils on the basis of column studies
Authors: Pietrzak Damian , Kania Jarosław , Kmiecik Ewa , Wątor Katarzyna 
Published: January 2020

Abstract
Knowledge of transport patterns of chemicals in groundwater is essential for environmental assessment of their potential impact. In the present study, the mobility of a chloride tracer injected into three different soils was investigated, using column experiments. The column tests were performed under steady-state conditions to determine parameters of chloride migration through soils. Based on breakthrough curves, pore-water velocity, dispersion coefficient and dispersivity constant were calculated for each soil sample using CXTFIT/STANMOD software. Pore-water velocity was in the range of 0.31 cm/min for fine sand, to 0.35 cm/min for silty sand and to 0.40 cm/min for vari-grained sand. The highest values of dispersion coefficient and dispersivity constant were observed for silty sand (0.55 cm2/min and 1.55 cm, respectively), while the lowest value was found for fine sand (0.059 cm2/min and 0.19 cm, respectively). Column experiments for chlorides (conservative tracer) are a preliminary stage for further research which will be undertaken to investigate migration parameters of selected neonicotinoids (reactive tracers) through different soils.
Presence of pharmaceutical compounds in groundwater with respect to land use in the vicinity of sampling sites
Authors: Kuczyńska Anna 
Published: January 2020

Abstract
The present paper discusses the results of an analysis of the impact of land use on the distribution of pharmaceuticals in groundwater samples collected during a pilot study of the contents of pharmaceuticals and hormones in ground-water taken from the national groundwater monitoring network of the Polish Geological Institute - National Research Institute. Samples were collected during monitoring campaigns from 160 groundwater monitoring sites in various land use types in 2016 and 2017. Samples were analysed for a total of 34 active substances, including natural and synthetic oestrogen hormones, cardiovascular and respiratory medications, analgesics and anti-inflammatories, antidepressants, antimicrobial drugs and anti-epileptics. Our study confirmed the presence of pharmaceuticals in 53 per cent of ground-water samples taken. Data show variations in the distribution of pharmaceuticals depending on land use type, which can thus be employed in pressure analysis and identification of sources of pollution.
A probabilistic approach to assessment of the quality of drinking water
Authors: Wątor Katarzyna , Kmiecik Ewa , Postawa Adam , Rusiniak Piotr 
Published: January 2020

Abstract
Knowledge of uncertainty in analytical results is of prime importance in assessments of compliance with requirements set out for the quality of water intended for human consumption. Assessments of drinking water quality can be performed using either a deterministic or a probabilistic method. In the former approach, every single result is referred directly to the parametric value, while in the probabilistic method uncertainty related to analytical results is taken into account during the decision-making process. In the present research, laboratory uncertainty and uncertainty determined on the basis of results of analyses of duplicate samples collected in two Polish cities were compared and used in the probabilistic approach of water quality assessment. Using the probabilistic method, more results were considered to be “above the parametric value”. Most excesses were observed when the maximum allowable uncertainty as set out in the Regulation of the Minister of Health of 7 December 2017 was used, which is due to the highest values of these uncertainties. The lowest values above parametric values in the probabilistic approach were observed when measurement uncertainty was considered.
The FEM model of groundwater circulation in the vicinity of the Świniarsko intake, near Nowy Sącz (Poland)
Authors: Zdechlik Robert , Kałuża Agnieszka 
Published: January 2020

Abstract
Modern hydrogeological research uses numerical modelling, which is most often based on the finite difference method (FDM) or finite element method (FEM). The present paper discusses an example of application of the less frequently used FEM for simulating groundwater circulation in the vicinity of the intake at Świniarsko near Nowy Sącz. The research area is bordered by rivers and watersheds, and within it, two well-connected aquifers occur (Quaternary gravelly-sandy sediments and Paleogene cracked flysch rocks). The area was discretized using a Triangle generator, taking into account assumptions about the nature and density of the mesh. Rivers, wells, an irrigation ditch and infiltration of precipitation were projected onto boundary conditions. Conditions of groundwater circulation in the aquifer have been assessed based on a calibrated model, using water balance and a groundwater level contour map with flow path lines. Application of the program based on FEM, using smooth local densification of the discretization mesh, has allowed for precise mapping of the location of objects that significantly shape water circulation.
The fate of socialist agricultural premises: To agricultural ‘brownfields’ and back again?
Authors: Navrátil Josef , Martinát Stanislav , Krejčí Tomáš , Pícha Kamil , Klusáček Petr , Škrabal Jaroslav , Osman Robert 
Published: January 2020

Abstract
The variety of post-socialist agricultural transitions in four different rural regions located in South Bohemia (Czech Republic), with respect to the utilisation of the older premises, is subject to analysis in this article. A complete database was constructed, containing the identification of agricultural premises in 1989 and their use in 2004 and 2017. From 1989 to 2004, a number of agricultural brownfields emerged, and many sites had been utilised for non-agricultural purposes. After 2004, the acreage of agricultural brownfields was reduced and new land-use utilisation for housing and, especially other non-agricultural activities, significantly increased. The transition in the utilisation of pre-1989 agricultural premises is strongly influenced by the social and economic contexts in which particular sites are located. Proximity to an upper-level regional centre is of crucial importance for decisions with respect to how (and if) the site will be reused. The peripheral location of the site also affects the level and the selection of options for the ways in which particular pre-1989 agricultural premises are used. In the case studies reported here, the marginality of particular regions is increased by their location in the border regions of outer peripheries, where the probability of the presence of agricultural brownfields and the probability of long-term abandonment of agricultural premises is higher. For the traditional developed countryside, we found a typical low level of the share of long-term agricultural brownfields. After 2004, the re-use of pre-1989 agricultural brownfields for agriculture was ascertained, which is complemented by their use for housing.
Freeze-thaw Damage Dependence on Wind-driven Rain of Outdoor Exposed Concrete – A Case Study
Authors: Pakkala Toni A. , Lahdensivu Jukka , Huuhka Petteri 
Published: January 2020

Abstract
It has been shown in previous studies that the existing precast concrete element building stock in Finland has quality issues, especially with freeze-thaw durability and reinforcement corrosion. In addition, it has been presented that deterioration rate is the fastest in coastal area and decreases towards north which has been supposed to be a reason of lower amount of wind-driven rain (WDR). The aim of this study was to examine the connection between the amount of WDR on structures and the freeze-thaw damage more comprehensively. Condition investigation reports of 472 precast concrete element buildings were reanalysed to study the relation and the results were compared to climate data of the same time period to study the correlation between condition investigation observations and the amount of WDR. In addition, the observations made in a condition investigations and their relation to climate load at the same building were studied as a case study. The results show that there is a significant connection between the WDR related climate load and the freeze-thaw damage occurrence. The results can be used to plan protective methods and be a base for service life estimations.
Effect of AEA-SP Dosage Sequence on Air Entrainment in FA Concrete
Authors: Shpak Andrei , Jacobsen Stefan 
Published: January 2020

Abstract
Laboratory measurements show that varying the dosage sequence of air-entraining agent and co-polymer in the mix (SP added before, after or together with AEA) greatly affects air entrainment in fresh and hardened fly ash concrete. Image analysis shows a somewhat lower specific surface when SP is added together with AEA. Foam Index measurements on the same binder materials, admixtures, and dosage sequences were therefore found less useful for studying the effect of admixture combinations. Obtaining a certain air content using the experience with AEA-SP dosage was found to be an untrivial task if there is a lack of parameter control. Finally, examples of successful mixing procedure for air entrainment in a series of high-volume fly ash concrete are shown.
Width and Edge Beam Effects on the Ultimate Behaviour of RC Bridge Overhangs
Authors: Veganzones José Javier , Pacoste Costin , Karoumi Raid 
Published: January 2020

Abstract
The bearing capacity of RC overhangs under concentrated loads can be dependent on the width of the slab. The goal of this paper is to investigate the effect of different widths using tests from the literature and non-linear FE-simulations as a reference. Shear force redistributions along the loading process and the shear concrete capacity are analysed. The shear effective width and the influence of an edge beam are also addressed. The results show that the bearing capacity of RC overhangs increase with the width until a transition area is reached and the increase flattens. An increased shear distribution sideways and posterior redistributions under the loading process are enabled. The shear capacity of concrete increases with the width and for loads close to the root an arch effect is observed. The edge beam contributes to a further increase of the ultimate capacity for wide enough overhangs. The effect of the width and the edge beam is not only quantitative but also qualitative since the failure mode and the critical section are influenced. Existing formulation for shear effective widths should be revisited. Experimental tests used for this purpose should consider wide enough specimens to capture the real behaviour of a bridge overhang slab.
The Choice of Materials for the E39 Fjord Crossing Project
Authors: Holtberget Simen Hellgren , Xiang Xu , Dørum Cato , Veie Johannes , Minoretti Arianna 
Published: January 2020

Abstract
In the studies for crossing the long and deep Norwegian fjords along the E39 road, on the west coast of Norway, some challenging structures have been evaluated. Some of them are known structures, like floating bridges, and some others are structures never built before, like suspension bridges on tension leg platforms and submerged floating tube bridges. In the development of the feasibility studies for these crossings, the choice of materials has played an important role. The materials influence not only the design and the cost, but also the behaviour of the structure towards the environmental loads and some particular loads as the ship collision. The article illustrates the different solutions proposed for the fjord crossings and discusses the influence in the choice of the material, with special regards to the type of concrete. The pros and cons of the application of the light weight concrete are discussed.
Topological and Size Optimization of RC Beam Bridges: An Automated Design Approach for Cost Effective and Environmental Friendly Solutions
Authors: Chalouhi Elisa Khouri , Pacoste Costin , Karoumi Raid 
Published: January 2020

Abstract
This work presents a procedure for the automated design and optimization of reinforced concrete beam bridges. The aim is to find solutions that minimize the investment cost and the environmental impact of the bridge. The complete structure is optimized including: number of spans, pier locations, pier-deck connections and deck dimensions. A detailed design of the deck reinforcement is included as well. Furthermore, constructability is considered and quantified within the investment cost to avoid a merely theoretical optimization. Genetic Algorithm (GA) and Pattern Search (PS) optimization algorithms are used. To reduce the computational time and make the procedure more user-friendly, a memory system is integrated and a modified version of GA is developed. In this paper, the proposed procedure is applied to re-design an existing bridge originally designed according to Eurocodes by an experienced engineer in 2013. Savings of 10-15% for both investment cost and environmental impact have been obtained. Finally, the proposed procedure has been applied to several alternatives with different total bridge lengths to suggest the optimal number of spans for a given total bridge length.
Bonded Concrete Overlays: A Brief Discussion on Restrained Shrinkage Deformations and Their Prediction Models
Authors: Cyron Wojciech , Nilsson Martin , Emborg Mats , Ohlsson Ulf 
Published: January 2020

Abstract
Bonded concrete overlays (BCO) on bridge decks are beneficial solutions due to their superior properties as compared to the typical asphalt pavement. A significant number of overlays suffer however, from occurrence of cracks and delamination due to poor bond, and restrained shrinkage and thermal dilation. Over the past years different appraisals for estimation of the restrained deformations have been developed, from micro-scale models, based on poromechanics, to empirical equations as given in B3 or B4 models suggested by Bažant. This paper provides a short overview of calculation models along with a brief theoretical explanation of shrinkage mechanism.