bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing Internet-Based Information used to aid patient decision-making for pelvic exenteration for locally advanced and recurrent rectal cancer
Authors: Williams Anwen , Cunningham Andrew , Hutchings Hayley , Harris Dean A , Harji Deena , Evans Martyn D 
Published: August 2020

Abstract
Background: To establish what online decision aids are currently available for patients contemplating pelvic exenteration (PE) for locally advanced and recurrent rectal cancer (LARC and LRRC). Methodology: A grey literature review was carried out using the Google SearchTM engine undertaken using a predefined search strategy (PROSPERO database CRD42019122933). Written health information was assessed using the DISCERN criteria and International Patient Decision Aids Standards (IPDAS) with readability content assessed using the Flesch-Kincaid score.Results: Google search yielded 27,782,200 results for the predefined search criteria. 131 sources were screened resulting in the analysis of 6 sources. No sources were identified as a decision aid according to the IPDAS criteria. All sources were deemed acceptable quality of written health information, scoring a global score of 3. for the DISCERN written assessment. The median Flesch-Kincaid ease was 50.85 (32.5-80.8) equating to a reading age of 15-18 years. Conclusions: This study has found that there is a paucity of online information for patients contemplating PE. Sources that are available are aimed at a high health literate patient. Given the considerable morbidity associated with this surgery there is a desperate need for high quality relevant information in this area. We would suggest the development of a PDA to improve decision making and ultimately improve patient experience.
Physical Distancing and Hand Washing During the COVID-19 Pandemic: The role of fear, perceived seriousness, and health knowledge
Authors: Krägeloh Christian U. , Alyami Mohsen , Alyami Hussain , Alwaily Mohammed , Alhuwaydi Ahmed M. , Henning Marcus A. 
Published: August 2020

Abstract
Background: To reduce the spread of COVID-19, physical distancing and hand washing has been widely promoted. However, more work is needed to understand the predictors of compliance with such health behaviors, such as fear of COVID-19. Methods: The Fear of COVID-19 Scale was administered to a sample of 1,029 Saudi participants recruited for an online survey. Analyses explored associations between fear of COVID-19 with demographic variables, frequency of physical distancing and hand washing, as well as perceived seriousness of COVID-19, and knowledge of recommended health behaviors and government restrictions. Results: Frequency of physical distancing and hand washing was overall very high. Fear of COVID-19 did not predict health behaviors. Knowledge of government restrictions predicted both physical distancing and hand washing, while perceived seriousness of COVID-19 also had a weak association with hand washing.Conclusion: Pandemic-related health behaviors such as physical distancing and hand washing do not appear to be motivated by fear in the present sample from Saudi Arabia. Interventions aimed at increasing compliance with recommended health behaviors thus benefit more from provision of relevant information.
Akibat Hukum Pencairan Kredit Yang Didasarkan Pada Covernote Notaris
Authors: Yusmi Silvia Anggraini 
Published: August 2020

Tujuan penelitian ini ialah untuk mengkaji dan menganalisis akibat hukum pencairan kredit yang didasarkan pada covernote notaris. Tipe penelitian yang digunakan dalam penelitian ini ialah penelitian yuridis normatif dengan menggunakan pendekatan undang-undang, pendekatan konseptual, dan pendekatan kasus. Hasil dari penelitian Covernote yang dibuat atas dasar kesepakatan Notaris dan Bank dalam pencairan kredit adalah sah, namun hanya berkedudukan sebagai surat keterangan dari notaris dan tidak memiliki kekuatan hukum karena tidak ada kewenangan Notaris dalam pembuatan suatu Covernote. Akibat hukum pencairan kredit yang didasarkan pada covernote Notaris adalah apabila tidak dapat diselesaikan pengurusan hak tanggungan sesuai dengan covernote yang dibuat oleh Notaris, maka berakibat objek jaminan dalam perjanjian hak tanggungan tidak dapat dieksekusi langsung atau perjanjian hak tanggungan batal demi hukum sedangkan perjanjian kreditnya belum berakhir. Covernote Notaris tidak memiliki kekuatan hukum untuk memberikan perlindungan hukum bagi bank selaku kreditur dalam perjanjian kredit apabila terjadi wanprestasi pada saat proses pembebanan hak jaminan. Notaris dapat dimintakan pertanggungjawaban atas kesalahannya jika dalam penerbitan covernote tersebut terdapat unsur yang memuat keterangan yang tidak benar terhadap isi covernote tersebut.
Kata Kunci: Covernote, Notaris, Perbankan
Status Badan Hukum Usaha Ekonomi Desa/Kelurahan Simpan Pinjam (UED/K-SP) di Kecamatan Bengkalis
Authors: Yalid Yalid 
Published: August 2020

ABSTRAK

Rumusan masalah dalam penelitian ini ada 3 (tiga). Pertama, Bagaimanakah pendirian badan hukum UED/K-SP di Kecamatan Bengkalis? Kedua, bagaimanakah hambatan pendirian badan hukum UED/K-SP di Kecamatan Bengkalis? Ketiga, bagaimanakah upaya mengatasi hambatan pendirian badan hukum UED/K-SP di Kecamatan Bengkalis? Sejalan dengan rumusan masalah tersebut maka tujuan penelitian ini pun ada 3 (tiga). Pertama, untuk menjelaskan pendirian badan hukum UED/K-SP di Kecamatan Bengkalis. Kedua,untuk menjelaskan hambatan pendirian badan hukum UED/K-SP di Kecamatan Bengkalis. Ketiga, untuk menjelaskan upaya mengatasi hambatan pendirian badan hukum UED/K-SP di Kecamatan Bengkalis. Jenis penelitianadalah penelitian hukum empiris untukmeninjau efektivitas berlakunya hukum. Lokasi penelitian di Kecamatan Bengkalis Kampar Kiri Hulu. Pertimbangan penulis memilih lokasi ini karena dari legalitas pembentukan UED/K-SP yang merupakan unit usaha BUMDesa di Kecamatan Bengkalis ditinjau dari perspektif hukum bertolak belakang dengan Undang-Undang Nomor 1 Tahun 2013 tentang Lembaga Keuangan Mikro (LKM).Hasil penelitian ini dapat dijelaskan pendirian badan hukum UED/K-SP di Kecamatan Bengkalis haruslah berbentuk badan hukum sesuai amanat Pasal 4 huruf a Undang-Undang Nomor 1 Tahun 2013 jo Pasal 8 Permendes PDTT Nomor 4 Tahun 2015. Hasil penelitian ini dapat diketahui tidak ada satupun UED-SP di Kecamatan Bengkalis yang sudah memenuhi persyaratan LKM dan berbadan hukum. Hambatan pendirian badan hukum UED/K-SP di Kecamatan Bengkalis dari hasil penelitian ini jawaban yang relevan hanyalah terkait peralihan aset, sedangkan jawaban selebihnya dari sampel penelitian tidak ada relevansinya dengan hambatan pendirian badan hukum UED/K-SP. Upaya mengatasi hambatan pendirian badan hukum UED/K-SP di Kecamatan Bengkalis tidak ada rencana dan tindakan konkrit untuk mengatasi hambatan dimaksud. Hal ini disebabkan karena seluruh sampel penelitian ini seluruhnya tidak memahami pendirian badan hukum UED/K-SP.

Kata Kunci: Status Badan Hukum, UED/K-SP, Kecamatan Bengkalis
Opposing Associations of NT-proBNP With Risks of Diabetes and Diabetes-Related Complications
Authors: Birukov Anna , Eichelmann Fabian , Kuxhaus Olga , Polemiti Elli , Fritsche Andreas , Wirth Janine , Boeing Heiner , Weikert Cornelia , Schulze Matthias B. 
Published: August 2020

OBJECTIVE
Circulating N-terminal pro B-type natriuretic peptide (NT-proBNP) is a classic diagnostic and prognostic marker for heart failure. However, it is inversely associated with diabetes risk. We aimed to investigate relationships of NT-proBNP with risk of diabetes-related complications in initially healthy individuals.

RESEARCH DESIGN AND METHODS
We performed a case-cohort study within the European Prospective Investigation Into Cancer and Nutrition (EPIC)-Potsdam cohort including a random subcohort (n = 1,294) and incident cases of type 2 diabetes (n = 649) and cardiovascular diseases (n = 478). Incident cases of type 2 diabetes (n = 545) were followed up for microvascular (n = 133) and macrovascular (n = 50) complications. Plasma NT-proBNP was measured at baseline in initially healthy participants.

RESULTS
In multivariable models, NT-proBNP was linearly inversely associated with incident type 2 diabetes with a hazard ratio (HR) (95% CI) per doubling in NT-proBNP of 0.91 (0.86, 0.98). The association was only observable in women (0.80 [0.72, 0.90]) compared with men (0.98 [0.91, 1.07]). Among people with incident diabetes, NT-proBNP was positively associated with diabetes complications: overall, 1.31 (1.13, 1.53); microvascular complications, 1.20 (1.01, 1.43); and macrovascular complications, 1.37 (1.03, 1.83).

CONCLUSIONS
Although higher NT-proBNP levels are associated with lower diabetes risk, NT-proBNP is a biomarker for vascular complications in people who develop diabetes independent of potential confounders. Thus, NT-proBNP might be informative to monitor risk for diabetes-related microvascular and macrovascular complications, which should be further explored in future prospective studies.
The Influence of Market Orientation and Product Innovation on the Competitive Advantage and Its Implication toward Small and Medium Enterprises (Ukm) Performance
Authors: Herman Hendri , Hady Hamdy , Arafah Willy 
Published: August 2020

This study aims to: (1) determine the effect of market orientation on competitive advantage; (2) to know the effect of innovation on competitive advantage; (3) to know the influence of market orientation and product innovation together to competitive advantage; (4) the effect of market orientation on the performance of SMEs, (5) to know the effect of product innovation on the performance of SMEs, (6) to know the effect of competitive advantage on SMEs performance, and (7) to know the effect of market orientation, product innovation, and competitive advantage together SMEs.
This research uses an explorative design that aims to conduct a search and reveal the factors that can be estimated as the cause of the occurrence of a condition that is not yet known the cause and the mechanism.The population in this study is the SMEs in Batam city with the type of production business with a population of 153 SMEs. The number of samples was determined using a saturated sample technique in which the entire population in the study was sampled. So the number of samples in this study was as many as 153 SMEs.
From the results of the study found that market orientation has a positive and significant impact on competitive advantage. Product innovation has a positive and significant impact on competitive advantage. Market orientation and product innovation together have a positive and significant impact on competitive advantage with R2 value of 83%. The dominant variable influencing competitive advantage is product innovation with regression coefficient value 0,62. Market orientation has a positive and significant effect on SME's performance. Product innovation has a positive and significant effect on SME's performance. Competitive advantage positively and significantly influence to SMEs performance, market orientation, product innovation and competitive advantage together have positive and significant influence to SMEs performance with R2 value equal to 90%. The dominant variable affecting the performance of SMEs is the advantage of competing with the value of regression coefficient 0.47.
This research offers implementation to SMEs to improve market orientation and product innovation so that it will increase competitive advantage which impact on SMEs performance.
Mathematical Modeling of Polyphosphazenes
Authors: Abid Amin , Hussain Shafiq , Qureshi Ahmad Kaleem , Jamil Muhammad , Rehman Hajira , Rauf Abdur 
Published: August 2020

Abstract
Polyphosphazenes was synthesized and their self assembly behavior was observed as reported in our previous work [1–5]. A number of experiments were carried out to study the polymerization behavior at various conditions of the polymerization time and temperature. The experimental data were analyzed by graphical and statistical methods and it was found that the polymerization phenomena was controlled by the synthesis time, i.e. Mw
= Mo ek
s
ts, where Mw
is molecular weight of the polymer at time ts, M
0(=203.24) is pre-exponential factor in the model and ks
is (=10686) is synthesis rate constant for the polymer.
Klippel-Trenaunay Syndrome Involving Upper Limb and Chest Wall: A Case Report and Review of the Literature
Authors: Mironova N. , Dourmishev L. , Botev I. , Miteva L. 
Published: August 2020

Abstract
The group of congenital limb overgrowth syndromes associated with vascular malformations include various disorders, often with variable clinical expression. Klippel-Trenaunay syndrome is the most common syndrome in this group, compared to other similar disorders such as Proteus, Parkes-Weber, Sturge-Weber, Cobb, Maffucii and CLOVES syndromes. We present a case of a 55-year-old male who presented with swelling, pain, heaviness, numbness and increased local temperature, involving the right upper extremity and the right side of the chest wall and associated with a livid erythema. The patient had several comorbidities including arterial hypertension and ischemic heart disease. He also had a family history of diabetes mellitus. A multidisciplinary team-based treatment approach, including physicians with expertise in various medical and surgical specialties was applied with the patient being “the unifying focus” of all these experts and their efforts. A personal approach tailored to the patient’s preferences was the key to a successful treatment.
Chylothorax After Cardiac Surgery
Authors: Vazhev Z. , Dimitrov K. , Stoev H. 
Published: August 2020

Abstract
In the following article we present a case of postoperative chylothorax as rare and severe complication after cardiac surgery. We present a case of 56-year-old man after double-valve replacement procedure and aorto-coronary artery bypass grafting, including pedicled left internal mammary artery towards left anterior descending artery. By the tenth postoperative day the total amount of drained milky white fluid from the left pleural cavity reached the colossal volume of 13 040 ml, despite the conservative therapy with intravenous Sandostatin (Octreotide) and parenteral feeding with a solution rich in medium chain triglycerides and amino acids – OliClínomel. The results of the biochemical analysis confirmed the diagnosis chylothorax. On the tenth postoperative day, a revision of the left pleural cavity through left thoracotomy was performed and lesion of the thoracic duct was identified. The lesion was sutured and secured with fibrin tissue glue – Tissucol for definitive treatment of the lymphorrhagia. The combined therapeutic and surgical approach concerning this serious complication turned out to be effective, and the patient was discharged on the thirty-second postoperative day with significant clinical improvement without ultra-sound and x-ray data for left pleural effusion.
Neurofibromatosis Type I (Von Recklinghausen Disease): A Case Report and Review of the Literature
Authors: Pozharashka J. , Dourmishev L. , Bardarov E. , Balabanova M. , Miteva L. 
Published: August 2020

Abstract
Neurofibromatosis type I is an autosomal dominant genetic disorder with an incidence of about 1 in 3000 births. Apart from the typical skin involvement NF1 may affect multiple organs with ocular, neurological, skeletal and cardiovascular manifestations. We present a case of a 38-year-old man with multiple café-au-lait macules and hundreds of neurofibromas disseminated on the trunk and extremities dating from childhood. To establish the diagnosis and to exclude any complications we performed multiple examinations, including skin biopsy, laboratory investigations, ophthalmologic assessment, consultations with a neurologist, internist and orthopedist, etc. The treatment of cutaneous NF1 is mainly symptomatic. Surgical excision aims to achieve cosmetic results. Recently novel and perspective conservative therapies have been investigated. In order to ensure better outcome for the patients with NF1 long-term multi-disciplinary approach is advised.
Bulk milk quality as affected by cattle breed composition of the herd in mountain area
Authors: Zanon Thomas , Costa Angela , De Marchi Massimo , Penasa Mauro , König Sven , Gauly Matthias 
Published: August 2020

Abstract
The aim of this study was to investigate the variation of gross composition, somatic cell count, urea content, and fatty acids (FA) composition of bulk milk from single-breed and multi-breed farms in alpine area, keeping either Brown Swiss (BS), Holstein Friesian (HF), Simmental (SI), or their combinations. Gross milk composition, urea content, and FA composition were predicted using mid-infrared spectroscopy. Observations were grouped in 7 combinations consisting of 3 singlebreed and 4 multi-breed types of herd. A mixed linear model was used for data analysis, accounting for the fixed effects of herd composition (7 combinations), month of sampling, year of sampling, and the interactions between herd composition and month of sampling, and between herd composition and year of sampling. Farm was included as random effect. Results highlighted that about two thirds of South Tyrolean farms were single-breed and herds with more than 20 lactating cows changed herd structure over time, switching from multi- to single-breed. Single-breed BS farms produced milk with greater fat, protein, casein, lactose, and FA content than single-breed HF and SI farms. Further, multi-breed herds including BS cows produced milk with greater fat, protein, casein, and polyunsaturated FA content than multi-breed HF+SI herds. Overall, single-breed SI farms produced milk with lower somatic cell count than other herd combinations. Despite the number of BS cows in South Tyrol has decreased in favor of SI in the last years, this breed is still the most interesting for alpine dairy farming to achieve optimal milk quality in both single- and multi-breed scenarios. The tendency to move to SI is mainly related to good milk performance of SI cows coupled with their robustness, high carcass value, high market value of calves, and adaptability to mountain farming system.
Chemical Composition of Algerian Thymus algeriensis Boiss. & Reut. and Marrubium vulgare L. (Lamiaceae) Essential Oils from the Aures Region
Authors: Kebbi Sara , Fadel Hamza , Chalchat Jean-claude , Figueredo Gilles , Chalard Pierre , Hazmoune Hichem , Benayache Fadila , Benayache Samir , Seghiri Ramdane 
Published: August 2020

Abstract
This study was aimed to determine the chemical composition of essential oils obtained from aerial parts of Thymus algeriensis Boiss. & Reut. and Marrubium vulgare L. collected in the Aures region of Algeria. Essential oils were extracted by steam distillation method and analyzed using GC-MS and GC-FID techniques. Thirty-five (35) and twenty-nine (29) components were identified respectively in T. algeriensis and M. vulgare essential oils to represent respectively 94.8% and 75.7% of the total oil composition. The main compounds of T. algeriensis oil were germacrene D (29.6%), β-caryophyllene (11.0%), E-β-farnesene (7.8%), bicyclogermacrene (4.4%) and δ-cadinene (4.0%), while, β-bisaboene (36.3%), β-caryophyllene (7.8%), phytol (6.2%), nonacosane (4.0%) and heptacosane (3.3%) were the main components of M. vulgare oil. The richness of these two oils in germacrene D and β-bisaboene respectively could suggest a new bioactivity.
Effect of seasonal variations on the content of some osmolytes of Aleppo pine and holm oak
Authors: Rached-Kanouni M. , Bousba R. , Khammar H. , Redjaimia L. , Kadi Z. , Ababsa L. 
Published: August 2020

AbstractThe forest of Chettaba is of great ecological importance for the Constantine region. It is characterized by a very heterogeneous forest cover, the dominance of forest species (Pinus halepensis and Quercus ilex) and an advanced stage of degradation. Vegetation in this region reflects the climate. The summer is dry and hot while the winter is rainy and cold. Indeed, the combination of rain and temperature directly influences the physiology of the vegetation in this forest. The main objective of this work is to characterize the different responses of Aleppo pine and holm oak seedlings and to specify the biochemical variations under the seasonal effect. Biochemical assays of proline, soluble sugars, total proteins and chlorophyll were quantified in the different organs of two species for each of the years 2018–2019. The results obtained show very significant accumulation of total soluble sugars and proline in holm oak and Aleppo pine leaves compared to stems and roots during the winter season (520 ± 20 and 370 ± 17.98 µmol/mg DM respectively). Contrary to the previous results, the highest total protein levels were recorded during the summer with levels of 0.666 ± 0.116 and 1,626 ± 0.107 mg/g FM. Parallel to the accumulation of these three solutes, a gradual decrease in the chlorophyll pigment content was recorded in winter and summer.
Impacts of anthropogenic pressure on the degradation of the forest of Doui Thabet (Saida, Western Algeria) in the context of the restoration
Authors: Ahmed Aouadj Sid , Yahia Nasrallah , Okkacha Hasnaoui , Hadj Khatir 
Published: August 2020

Abstract
The forest of Doui Thabet is one of the forests of the Mounts of Saida (Western Algeria) which is experiencing a dynamic regressive. Located in the semi-arid bioclimatic stage, it is located at the edge of two phytogeographic sub-sectors: atlas Tellien Oranais (O3) and high plateau subsector (H1). Among the factors that threaten to curb this fragile and weakened ecosystem, in addition to drought and climate aridity and which has become a structural ecological phenomenon; the overgrazing is also a major limiting factor. This current study provides a qualitative and quantitative assessment of anthropogenic pressure exerted in this area zone. The methodology adopted in this study is that of Le Houerou (1969) and Montoya (1983), which it is based on the calculation of the annual needs of the herd in forage units, the estimate of the feed potential of production, the coefficient of overgrazing and in addition to the anthropogenic pressure index. The result of the forage balance in the forest rangelands of the studied area has a forage deficit (overload) of (96.64%) (a sylvopastoral imbalance), in addition to that, the coefficient of overgrazing is (92.3%) and the anthropogenic pressure index is very high (28). The conservation and the restoration of this area is a major concern in the face of global changes, taking into account their mode of reproduction and their dynamics, for the development of restoration strategies and more effective ways of protection.
New ideas about the Balkan peninsula East Part morphotectonics
Authors: Tzankov Tzanko , Stankova Svetla 
Published: August 2020

Abstract
The article introduces the results of the author’s new investigations about the origin, Quaternary morphotectonic evolution and the modern morphostructure of the Bulgarian Continental Microplate in the eastern part of Balkan Peninsula. The research was realized on a base of the contemporary Plate tectonic study principia by means of the morphostructural analysis apply. It was provided the principal relief building role of the regional mosaic pattern and the listric faulting in the Balkan Peninsula East Part.