bluuebunny/crossref_metadata_2025_split huggingface dataset:
From an invariant sensory code to a perceptual categorical code in secondary somatosensory cortex
Authors: Pool Román Rossi , Zainos Antonio , Alvarez Manuel , Leon Gabriel Diaz-de , Romo Ranulfo 
Published: July 2020

Abstract
A crucial role of cortical networks is the conversion of sensory inputs into perception. In the cortical somatosensory network, neurons of the primary somatosensory cortex (S1) show invariant sensory responses, while frontal lobe neuronal activity correlates with the animal’s perceptual behavior. Here, we report that in the secondary somatosensory cortex (S2), neurons with invariant sensory responses coexist with neurons whose responses correlate with perceptual behavior. Importantly, the vast majority of the neurons fall along a continuum of combined sensory and categorical dynamics. These distinct neural responses exhibit analogous timescales of intrinsic fluctuations, suggesting that they belong to the same hierarchical processing stage. Furthermore, during a non-demanding control task, the sensory responses remained unaltered while perceptual responses vanished. Sensory information increased and categorical information diminished during this control task, suggesting that processing depended on the task context. Conclusively, S2 neurons exhibit intriguing dynamics that are intermediate between S1 and frontal lobe.
Psychosocial Factor Identification in Cancer Patient Community
Authors: Moamen Ibrahim , Oussalah Mourad , Ackers Dan , Gilman Ekaterina , Miettunen Jouko 
Published: August 2020

Abstract
BackgroundThe open Suomi24 discussion forum, Finland’s largest topic-centric social media, provides excellent opportunities to study users’ interactions with various contemporary discussion topics. Its easy access and anonymity enable patient and users to seek valuable advices or share their experiences. This paper focuses primarily on cancer health users’ discussion forum and attempts to lie down foundations for content-analysis based approach for identifying psychosocial factors of patient cancer community in Suomi24.MethodThe methodology utilizes to a large extent innovative natural language processing based approach that calls for ontology based construction for identifying the relevant discussion threads in Suomi24 corpus. Next, a co-occurrence analysis with various distance level was employed to quantify the strength of the co-occurring words. Inspired by psychosocial factors analysis in related medical studies, a categorization for psychosocial factors has been put forward and investigated.ResultsThe results overlap to a large extent with some previous findings in clinical studies where the dominance of the social factors is highly reported. An open platform has been put forward to help both researchers and clinicians to study the Suomi24 collected dataset, with the potential correlation analysis with patient records through dedicated electronic medical record databases.ConclusionThis work paves the way for further investigation of medical textual data in order to correlate the finding with patient records as registered in electronic medical records. Besides, the analysis also highlights the challenge of accommodating standard NLP tools to Finnish language where more work is needed in order to match the performance of the available tools in English textual analysis.
A Preliminary Multicenter Evaluation of Endoscopic Sublay Repair for Ventral Hernia From China
Authors: Tang Rui , Jiang Huiyong , WU Weidong , Wang Tao , Meng Mengxiang , Liu Guozhong , Cai Xiaoyan , Liu Jianwen , Cui Xijun , Si Xianke , Liu Nan , Wei Nina 
Published: July 2020

Abstract
Background
For ventral hernia, endoscopic sublay repair (ESR) may overcome the disadvantages of open sublay and laparoscopic intraperitoneal onlay mesh repair. This retrospective study presents the preliminary multicenter results of ESR from China. The feasibility, safety, and effectiveness of ESR were evaluated; its surgical points and indications were summarized.
Methods
The study reviewed 156 ventral hernia patients planned to perform with ESR in ten hospitals between March 2016 and July 2019. Patient demographics, hernia characteristics, operative variables, and surgical results were recorded and analyzed.
Results
ESR was performed successfully in 153 patients, 135 with totally extraperitoneal sublay (TES) and 18 with transabdominal sublay (TAS). In 19 patients, TES was performed with the total visceral sac separation (TVS) technique, in which the space separation is carried out along the peritoneum, avoiding damage to the aponeurotic structure. Endoscopic transversus abdominis release (eTAR) was required in 17.0% of patients, and only 18.3% of patients required permanent mesh fixation. The median operative time was 135 min. Most patients had mild pain and resume eating soon after operation. No severe intraoperative complications occurred. Bleeding in the extraperitoneal space occurred in two patients and was stopped by nonsurgical treatment. Seroma and chronic pain were observed in 5.23% and 3.07% of patients. One recurrence occurred after TAS repair for an umbilical hernia.
Conclusion
ESR is feasible, safe, and effective for treating ventral hernias when surgeons get the relevant surgical skills, such as the technique of “partition breaking,” TVS, and eTAR. Small-to-medium ventral hernias are the major indications.
Maternal Vaccinations Coverage And Reasons For Non-Compliance - A Cross-Sectional Observational Study
Authors: Drezner David , Youngster Michal , Klainer Hodaya , Youngster Ilan 
Published: July 2020

Abstract
Background: Maternal influenza and pertussis vaccination has been proven a safe and effective strategy to reduce maternal and infant morbidity and mortality. Though recommended, not all pregnant women receive these important vaccinations. We aimed to evaluate the vaccine coverage of maternal immunization in pregnancy for seasonal influenza and acellular pertussis and elucidate the reasons for non-vaccination among pregnant women. The secondary objective was to describe factors that affect vaccine uptake.Methods: A cross sectional observational study using anonymous questionnaires distributed to women in the maternity ward or pregnant women (>37 weeks) hospitalized in the high-risk ward, thru Nov 2017-June 2018.Results: Of 321 women approached, 313 were eligible and 290 questionnaires were retrieved (92.6%). We found a 75.9% (95% CI 0.71, 0.81) and 34.5% (95% CI 0.29, 0.40) vaccination rate for pertussis and influenza vaccines respectively. The most prominent reason for not receiving the pertussis vaccination was being under-informed (24%). Influenza vaccine was not received mainly due to concerns about vaccine efficacy (28%). Other factors influencing vaccination uptake included education, prior childbirth and vaccine recommendations made by the provider.Conclusion: Although maternal vaccination of pertussis and influenza is officially recommended, vaccine uptake is suboptimal. Our study suggests a central role for medical providers in diminishing the concerns about safety and efficacy, and presents novel factors influencing compliance rates, like seasonality and number of prior births.
Primary Total hip Arthroplasty Using A Short Bone-Conserving Stem in Young Adult Osteoporotic Patients with Dorr type C Femoral Bone
Authors: Zhen Ping , Chang Yanfeng , Yue Heng , Chen Hui , Zhou Shenghu , Liu Jun , He Xiaole 
Published: July 2020

Abstract
Background: Dorr Type C femoral bone exhibits a wide, stovepipe-shaped femoral canal and thin cortices in the proximal femur. Dorr C bone combined with severe osteoporosis is an important challenge in primary hip arthroplasty. In this study, we assessed the effects of short metaphyseal fitting cementless stems on preformatted primary total hip arthroplasties in young adult osteoporotic patients with this femoral presentation.Methods: A total of 42 hip arthroplasties were performed in 35 young patients (range, 20 to 36 years) using a short Tri-lock bone preservation metaphyseal-fitting cementless femoral component between 2012 and 2017. The mean age at surgery of the 27 male (33 hips) and 8 female (9 hips) patients was 27.5 ± 3.7 years (range 20.3 to 35.8 years). The mean body mass index (BMI) was 20.2 kg/m2 (range, 16.8–23.2 kg/m2). According to Dorr’s criteria, all 42 femora were classified as type C bone and all femurs suffered from severe osteoporosis (Singh index≤3). Results: The mean follow-up period was 5.5 ± 1.1 years (range, 3.0–8.0 years). The clinical and functional results improved for the Harris hip score, WOMAC, and UCLA activity scores. The Harris Hip score improved from 48.0 ± 8.0 (range 38.0 to 61.0) preoperatively to 87.0 ± 9.0 (range 77.0 to 92.0) at 12 months after surgery and 91.0 ± 8.0 (range 85.0 to 98.0) at final follow-up. The preoperative UCLA activity score was 3.0±0.5 points (range, 1.0–4.0 points), which significantly improved to 7.5±0.7 points (range, 6.0–8.0 points) at the final follow-up. No patient exhibited thigh pain at the final follow-up. The mean stem-to-canal fill percentages were 97% ± 2.1% (anteroposterior view at midstem). For stem alignment, 40 hips (95.2%) of the femoral stem were positioned neutral to 3° of varus with reference to the femoral shaft axis. The remaining two were positioned at 4° varus to 4° valgus. Radiographic evaluation showed good osteointegration of the implants in follow-up.Conclusions: Based on the tapered-wedge design and proximal porous coating, the shortened tapered conventional stem can achieve reliable stability through neck filling and metaphyseal fixation, which does not depend on the isthmus hoop stress. This stem was suitable in severe osteoporotic patients with Type C bones in young adults who presented with a correspondingly straightened femoral canal with a wide isthmus and thin cortex.
Are Clinical Practice Guidelines of Low Back Pain interventions of high quality and updated? A systematic review using the AGREE II instrument
Authors: Castellini Greta , Iannicelli Valerio , Briguglio Matteo , Corbetta Davide , Sconfienza Luca Maria , Banfi Giuseppe , Gianola Silvia 
Published: July 2020

Abstract
BACKGROUND: Clinical practice guidelines (CPGs) provide specific recommendations for practice but, due to the increasing number of CPGs developed by multiple organisations over the last years, there are concerns about their quality. The aim is to systematically appraise the CPGs quality for low back pain (LBP) interventions and explore the inter-rater reliability (IRR) among quality appraisers. Time span intended as time from systematic reviews searches to CPGs publication was also assessed.METHODS: We undertook comprehensive searches in Pubmed, Embase, PEDro, TRIP, guideline organisation databases, websites and grey literature from January 2016 to March 2019 to identify all GPCs focus on rehabilitative, pharmacological or surgical interventions for LBP management. Four reviewers independently apprised the selected GPCs by using the Appraisal of Guidelines for Research and Evaluation II-AGREE II tool. Year of CPGs publication and year of search strategies were collected. RESULTS: 21 CPGs met the inclusion criteria and were appraised. Seven (33%) had a broad scope involving surgery, rehabilitative or pharmacological interventions. The guidelines achieved the following scores for each AGREE II item: Editorial Independence (median 67%, interquartile range [IQR] 31 – 84%), Scope and Purpose (median 64%, IQR 22 – 83%), Rigour of Development (median 50%, IQR 21 – 72%), Clarity and Presentation (median 50%, IQR 28 – 79%), Stakeholder Involvement (median 36%, IQR 10 – 74%) and Applicability (median 11%, IQR 0 – 46%). The IRR among assessors was nearly perfect (ICC 0.90; 95% CI 0.88 – 0.91). We observed a median time span of 2 years (range 1-4) however, 38% of CPGs did not report the coverage dates for systematic searches.CONCLUSIONS: We found methodological limitations affecting the CPGs quality. We call for a universal database where all guidelines can be registered and recommendations can be dynamically developed through a living systematic reviews approach ensuring the most updated evidence. LEVEL OF EVIDENCE: 1REGISTRATION PROSPERO DETAILS: CRD42019127619.
A formative quality improvement implementation study to improve care transitions through information capture upon admission to an acute mental health ward
Authors: Tyler Natasha , Wright Nicola , Gregoriou Kyriakos , Waring Justin 
Published: July 2020

Abstract
Background:

Many interventions have been developed that aim to improve the transition from ward to community at the time of discharge, with varying success. Guidelines suggest that discharge planning should begin at admission, but in reality this is ideal rather than standard practice. This quality improvement aims to develop a novel intervention that improves mental health care transitions by providing a framework for capturing relevant information at admission that facilitates and accelerates discharge.
Methods:

A formative implementation study to co-design, implement and evaluate a novel tool that improves information capture upon admission to acute mental health wards within a single English National Health Service (NHS) trust. Two cycles of PDSA were completed which included two workshops based on the principles of co-design. During implementation the tool was piloted on three wards. Ethnographic observations (145 hours) and interviews (45) were used to evaluate the implementation of the tool across the three wards. The consolidated framework for implementation research was used to analyse and categorise the qualitative data generated.
Results:

The tool developed considerably as the process evolved. The finished product is a list of 10 information categories that should be captured from external agencies upon admission to facilitate discharge planning. The most reported advantages of the tool were: 1) facilitating confidence in junior staff to legitimately question the suitability of a patient for an acute ward 2) collecting and storing essential information in a single accessible place that can be used throughout the care pathway and 3) collecting information from the services/agencies that patients will eventually be discharged to. The consolidated framework analysis highlighted multiple barriers to implementation from both an outer and inner setting perspective.
Conclusions:

The results suggest that improving the quality of information captured upon admission has the potential to facilitate and accelerate discharge. The novel tool provides a framework for capturing this information that can be incorporated into existing information systems.
Cross-Cultural Adaptation, Translation, and Moroccan Validation of CareGiver Oncology Quality of Life (CarGoQoL) questionnaire
Authors: AITOUMA AHLAM , Hind Mrabti , Bouchra Haddou Rahou , Rachid Razine , Hassan Errihani 
Published: August 2020

Abstract
Objective

The aim of this study is to validate the Moroccan version of The Caregivers Oncology Quality of Life (CarGoQol) questionnaire to measure the caregiver’s quality of life of palliative cancer patients in Morocco.
Results

The psychometric properties of CarGoQoL were generally good. A Cronbachα coefficient of 0.82 was obtained indicating a good internal consistency except for the private life dimension (α = 0.14). A good reliability of the test re-test was also observed, with an item internal consistency of 0.9. Missing data and ceiling effect were low; some ceiling effects were observed for Relationship with healthcare (38.9%); correlations were confirmed between the different dimensions that corresponding to the same domain; significant association was identified for caregiver and patient characteristics.
The Prevalence of ACME-arcA and PVL Genes Among Staphylococcus Aureus Isolates in a Student Population from North-West of Iran
Authors: Dehnad Alireza , Rad Rana Khosravi , Rahbarnia Leila , Naghili Behrooz , Golipor Aysan 
Published: July 2020

Abstract
Objectives: Staphylococcus aureus (S. aureus) is the most prevalent cause of skin infections, especially in colonized individuals. Panton–Valentine leukocidin (PVL) and Arginine catabolic mobile element (ACME) are known as the most common virulence factors of S. aureus. This cross-sectional study was conducted to examine the prevalence of ACME-arcA and PVL genes among S.aureus isolates in the student population. Nasal swab samples were randomly collected from 400 healthy students from Tabriz, Iran. The antibiotic resistance pattern of S.aureus isolates was examined by the disk diffusion method. The presence of ACME-arcA, PVL, and mecA genes was detected by PCR reaction.Results: overall, 15% (60/400) students were nasal carriage of S. aureus and 2.75 % (11/400) were MRSA carriage. The frequency of mecA, ACME-arcA, and PVL genes was 54.54% (36/60), 46.66% (28/60), and 16.66% (10/60) respectively. The prevalence of ACME-arcA and PVL genes was independent of gender (P =0.142, P=0.337, respectively). A notable association was observed between the existence of ACME-arcA gene and the frequency of mecA gene (P <0.05), while the incidence of PVL was independent on mecA. These findings highlight the necessity of monitoring nasal carriers in a healthy community to prevent subsequent infections.
Effect of COVID-19 Pandemic on Anxiety Depression And Intention To Go To Hospital in Chronic Patients
Authors: Kaya Yasemin , Bostan Sedat , Kaya Ahmet , Karaman Ömer , Karataş Ahmet , Dereli Seçkin 
Published: July 2020

Abstract
Objective: The aim of this study was to investigate the effects of COVID-19 pandemic on anxiety depression and intention to go to hospital in chronic patients.Methods: The Bostan Intention to Go to Hospital Scale developed by one researcher (SB) as the data collection tool and the Beck Anxiety-Depression Inventories were used.Results: 56.8% of the patients stated that they would go to the hospital in case of emergency and 28.3% expressed that they did not want to go to the hospital even in this case. 50% of the patients said that they did not want to go to the hospital under any circumstances during the pandemic process. As a result of the correlation analysis, there were inverse correlation between the anxiety-depression levels and encountering COVID patient and having a relative with COVID (p=0.001). Inverse correlation was found between intention to go to hospital and encountering COVID patient (p=0.001).Conclusion: It was revealed that chronic patients did not have any intentions to go to hospital during the COVID-19 pandemia and only half of people were willing to go to hospital in case of emergency. Anxiety and depression levels were found to increase when COVID patient was encountered or a relative had COVID.
The Effect of Closed Area on Woody Species Regeneration: A Case study in Loma Bosa Woreda, Dawuro zone, Southern Ethiopia
Authors: Ambushe Assefa Ataro , Gebre Girma Gezimu 
Published: July 2020

Abstract
This study examines the effect of closed area on woody species regeneration by comparing the woody species regeneration among closure, open woodland, and degraded land areas in Loma Bosa district, Dawuro zone in southern Ethiopia. Results show that Simpson's Diversity Index was 7.24 for woody species in closed area, 6.01 in open woodland and 3.40 in open degraded land area. Shannon-Weiner Diversity Index(H') was 2.26 for woody species in closed area, 2.38 in open woodland area and 1.56 in open degraded land area. The results of Sorenson's similarity coefficients indicates woody species composition in closed area are highly correlated with open woodland areas. Wood species density were 2,225 ha-1, 1,642 ha-1, and 297 ha-1 for closed area, open woodland area, and open degraded land area, respectively. The results indicate that closed area development enhanced species composition, richness, diversity, woody vegetation regeneration, inverted J shape Diameter at Breast Height (DBH) and height class and higher woody species density and crown cover class percentage compared to open degraded area. Overall results from this study indicated that area closure is important for improvement of woody species regeneration in the study area.
Working condition and health status of 6,317 front line public health workers during the COVID-19 epidemic across 5 provinces in China: a cross-sectional study
Authors: Li Jinghua , Xu Jingdong , Zhou Huan , You Hua , Wang Xiaohui , Li Yan , Liang Yuan , Li Shan , Ma Lina , Zeng Jing , Cai Huanle , Xie Jinzhao , Pan Chenghao , Hao Chun , Gilmour Stuart , Lau Joseph Tak-fai , Hao Yuantao , Xu Dong Roman , Gu Jing 
Published: July 2020

Abstract
Background: Public health workers at China CDCs and primary health care institutes (PHI) constitute one of the main workforces for implementing prevention and control measures to contain the COVID-19 epidemic, but their efforts and health status have not been well documented. We aimed to investigate the working conditions and health status of frontline public health workers in China during the epidemic. Methods: Between February 18 to March 1, 2020, we conducted a cross-sectional survey among 2,313 CDC workers and 4,004 PHI workers in five provinces across China experiencing different scales of COVID-19 epidemic. We interviewed all participants about their work conditions, roles, burdens, perceptions, mental health, and self-rated health by self-constructed questionnaire and standardized measurements. To examine the independent associations between working conditions and health outcomes, we used multivariate regression models controlling for potential confounders. Results: The prevalence of depression, anxiety, and poor self-rated health was 21.3%, 19.0%, and 9.8%, respectively, among public health workers (27.1%, 20.6% and 15.0% among CDC workers; and 17.5%, 17.9% and 6.8% among PHI workers). The majority (71.6%) participated in both field and non-field work and gave immense efforts. Nearly 20.0% have worked all night for more than 3 days and 45.3% had worked during the whole period of Chinese New Year. Three risk factors and two protective factors were found independently associated with all three health outcomes in our final multivariate models, including working all night for >3 days (ORm=1.67~1.75, p<0.001), concerns about being infected at work (ORm=1.46~1.89, p<0.001), perceived troubles at work (ORm=1.10~1.28, p<0.001), starting COVID-19 prevention work after January 23 (ORm=0.78~0.82, p=0.002~0.008), and capability to persist for more than 1 month at the current work intensity (ORm=0.44~0.55, p<0.001). Conclusion: Chinese public health workers gave immense efforts and personal sacrifices to curb the COVID-19 epidemic and were exposed to risk of mental health problems. Efforts should be taken to improve the working condition and health status of public health workers to maintain the morale and effectiveness of public health workers in the fight against the epidemic.