bluuebunny/crossref_metadata_2025_split huggingface dataset:
Future research avenues of cost of quality: a systematic literature review
Authors: Dimitrantzou Christina , Psomas Evangelos , Vouzas Fotios 
Published: March 2020

PurposeThe purpose of this paper is to identify the future research suggestions which have been made by several authors with regard to cost of quality (CoQ) and to group them into respective themes.Design/methodology/approachThis study was based on a systematic literature review (SLR) of 97 peer-reviewed journal articles in the field of CoQ published in well-known academic databases, such as Emerald, Elsevier, SpringerLink, Taylor & Francis, Wiley and Scopus. The time horizon for reviewing the literature was 9 years, particularly in the period between 2010 and 2018. The “Affinity diagram” was applied to group the future research suggestions into logical themes and the “Pareto diagram” to further categorize and prioritize these themes.FindingsA plethora of future research suggestions identified in the literature are analytically presented. Moreover, the analysis showed that the future research suggestions in the field of CoQ can be grouped under eleven meaningful themes, which are further categorized into two broad categories, meaning the vital and the useful.Research limitations/implicationsThis SLR was based on only fully accessed English articles published in international, peer-reviewed journals of the selected publishers. The restricted number of keywords used and the subjectivity in applying the “affinity diagram” are also limitations of this study.Practical implicationsThis paper provides insights into the future research perspectives in the field of CoQ. Thus, this analysis can serve as a resource for both researchers and practitioners to further develop this area according to the future research suggestions and the respective themes revealed.Originality/valueTo the best of the authors' knowledge, this is the first SLR presenting and analyzing the future research suggestions of CoQ.
Fostering the development of Oman’s knowledge economy pillars through ICT
Authors: Al-Busaidi Kamla Ali 
Published: March 2020

Purpose
Information and communications technology (ICT) is the driving force and key enabler of a knowledge economy. The purpose of this study is to identify the critical ICT indicators that foster the development of the knowledge economy and its main pillars (education, innovation and economic and institutional regimes) in Oman.

Design/methodology/approach
The study used a qualitative approach and conducted four Delphi studies on four groups of experts (ICT experts, educators, innovation experts and economists) in Oman.

Findings
The results indicated that the most commonly top-listed ICT indicators of a boost in the country’s knowledge economy are related to the national level (total research and development expenditure on ICT, ICT patents as a percentage of national total and ICT as an overall priority for the government), firm level (the proportion of businesses using the internet, the proportion of businesses using computers and the proportion of businesses with a Web presence), and inhabitant level (mobile phone subscribers per 100 inhabitants, internet subscribers per 100 inhabitants and personal computers per 100 inhabitants).

Originality/value
ICT is the driving pillar of a knowledge economy. The literature indicated that most of the ICTs for development studies are conducted in developed countries; hence, there is a great need for investigations in the context of less developed economies such as Oman. This study can provide insights for the country on how to develop and exploit ICT to boost the development of the overall knowledge economy and its pillars and to provide guidance for exploiting ICT to gain economic value. Oman’s vision for 2020 and 2040 aims at economic diversification; the knowledge economy is a critical aspect of the country’s economic diversification. In addition, the literature indicated that the relationship between ICT and development is still not clear; hence, this study provided some insights into the context of knowledge economy development.
Reflections on the theme issue outcomes the fourth industrial revolution
Authors: Ajagunna Ibrahim , Pinnock Fritz , Johnson Evette Smith , Teare Richard 
Published: March 2020

Purpose
The purpose of this paper is to profile the WHATT theme issue: “The fourth industrial revolution: What are the realities for maritime- and tourism-dependent countries?”, with reference to the experiences of the theme editors and writing team.

Design/methodology/approach
Structured questions were used to enable the theme editors to reflect on the rationale for the theme issue question, the starting point, the selection of the writing team and material and the editorial process.

Findings
This paper identifies the ways in which both industry and education need to change and embrace emerging technologies with particular reference to tourism and maritime provision and infrastructure in the Caribbean region.

Practical implications
The theme issue outcomes provide indicators and action points for tourism and maritime industry stakeholders and for academics involved in planning and delivering learning support to these industries.

Originality/value
This paper draws on discussion and applied research with industry to identify and assess the likely impact of the fourth industrial revolution in tourism- and maritime-dependent countries. Taken together, the theme issue collection of articles provides a rich picture of the changes occurring and prospects for the future.
Early‐life learning ability predicts adult social structure, with potential implications for fitness outcomes in the wild
Authors: Langley Ellis J. G. , van Horik Jayden O. , Whiteside Mark A. , Beardsworth Christine E. , Weiss Michael N. , Madden Joah R. 
Published: March 2020

Abstract

Social environments influence important ecological processes and can determine how selection acts on traits. Cognitive abilities can shape these social environments and in turn, affect individuals' fitness.

To understand how cognitive abilities evolve, we need to understand the complex interplay between an individual's cognitive abilities, the social environment that they inhabit and the fitness consequences of these relationships.

We measured the associative learning ability of pheasant chicks, Phasianus colchicus, then released them into the wild where we quantified their social position by observing their associations at feeding stations and monitored the number of days survived.

We observed disassortative mixing by learning performance at the population level, and poor learners had more associates than good learners. Learning was beneficial for survival when focal individuals had fewer than four associates, but survival probability across learning abilities equalized for individuals with more than four associates.

While the mechanisms underlying these relationships remain to be determined, the patterns of association exhibited by pheasants at feeders can be predicted by individual variation in cognitive performances and we suspect these patterns are related to differences in information use. Critically, these resulting patterns of association have fitness consequences for individuals that cannot be explained directly by their cognitive ability, but which could mediate selection on cognition.
Justifying Social Impact as a Form of Impression Management: Legitimacy Judgements of Social Enterprises’ Impact Accounts
Authors: Molecke Greg , Pinkse Jonatan 
Published: March 2020

AbstractThis paper investigates how social enterprises construct accounts to gain legitimacy from the social impact generated by their products and operations. The paper finds that social impact accounts are framed to appeal to two distinct forms of judgement about legitimacy: cognitive and evaluative. Cognitive forms of judgement qualify how well an enterprise shares attributes with an individual's schemas of established actors or roles in society. Evaluative forms of judgement tend to operate more analytically to make comparisons of the relative appropriateness and desirability of multiple enterprises to achieve an audience's goals. The findings show that although legitimizing the social aspects of an enterprise involved justifications aimed at both forms of judgement, legitimizing an enterprise's professionalism relied almost exclusively on evaluative judgements. Moreover, the justifications created to appeal to evaluative judgements relied almost exclusively on financial and operational data, using operational scale as a proxy.
Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence
Authors: Luo Xingguang , Guo Xiaoyun , Luo Xingqun , Tan Yunlong , Zhang Ping , Yang Kebing , Xie Ting , Shi Jing , Zhang Yong , Xu Jianying , Zuo Lingjun , Li Chiang‐Shan R. 
Published: March 2020

AbstractThe gray matter volume (GMV) of the putamen has been reported to be regulated by kinectin 1 gene (KTN1). As a hub of the dopaminergic circuit, the putamen is widely implicated in the etiological processes of substance use disorders (SUD). Here, we aimed to identify robust and reliable associations between KTN1 SNPs and SUD across multiple samples. We examined the associations between SUD and KTN1 SNPs in four independent population‐based or family‐based samples (n = 10,209). The potential regulatory effects of the risk alleles on the putamen GMVs, the effects of alcohol, nicotine, marijuana and cocaine on KTN1 mRNA expression, and the relationship between KTN1 mRNA expression and SUD were explored. We found that a total of 23 SNPs were associated with SUD across at least two independent samples (1.4 × 10−4 ≤ p ≤ 0.049), including one SNP (rs12895072) across three samples (8.8 × 10−3 ≤ p ≤ 0.049). Four other SNPs were significantly or suggestively associated with SUD only in European‐Australians (4.8 × 10−4 ≤ p ≤ 0.058). All of the SUD‐risk alleles of these 27 SNPs increased (β > 0) the putamen GMVs and represented major alleles (f > 0.5) in Europeans. Twenty‐two SNPs were potentially biologically functional. Alcohol, nicotine and cocaine significantly affected the KTN1 mRNA expression, and the KTN1 mRNA was differentially expressed between nicotine or cocaine dependent and control subjects. We concluded that there was a replicable and robust relationship among the KTN1 variants, KTN1 mRNA expression, putamen GMVs, molecular effects of substances, and SUD, suggesting that some risk KTN1 alleles might increase kinectin 1 expression in the putamen, altering putamen structures and functions, and leading to SUD.
Safety guideline: neurological monitoring associated with obstetric neuraxial block 2020
Authors: Yentis S. M. , Lucas D. N. , Brigante L. , Collis R. , Cowley P. , Denning S. , Fawcett W. J. , Gibson A. 
Published: March 2020

SummarySerious neurological lesions such as vertebral canal haematoma are rare after obstetric regional analgesia/anaesthesia, but early detection may be crucial to avoid permanent damage. This may be hampered by the variable and sometimes prolonged recovery following ‘normal’ neuraxial block, such that an underlying lesion may easily be missed. These guidelines make recommendations for the monitoring of recovery from obstetric neuraxial block, and escalation should recovery be delayed or new symptoms develop, with the aim of preventing serious neurological morbidity.
Four different ileorectal anastomotic configurations following total colectomy
Authors: Jolly Samantha , Dudi‐Venkata Nagendra N. , Hanna‐Rivero Nicole , Kroon Hidde M. , Reid Fiona S. W. , Sammour Tarik 
Published: March 2020

AbstractIleorectal and ileosigmoid anastomoses are typically performed following total colectomy and subtotal colectomy, respectively. The current literature provides extensive description of more common anastomoses such as after right hemicolectomy or anterior resection. However, there is little focus in the literature on the ileorectal or ileosigmoid anastomotic technique, despite these anastomoses having a relatively high complication rate. The purpose of the current study is to describe four standardized ileorectal or ileosigmoid anastomotic configurations, with commentary on specific challenges and theoretical advantages and disadvantages of each.
Slipping on slippery slope arguments
Authors: Fumagalli Roberto 
Published: March 2020

AbstractSlippery slope arguments (SSAs) are used in a wide range of philosophical debates, but are often dismissed as empirically ill‐founded and logically fallacious. In particular, leading authors put forward a meta‐SSA which points to instances of empirically ill‐founded and logically fallacious SSAs and to the alleged existence of a slippery slope leading to such SSAs to demonstrate that people should avoid using SSAs altogether. In this paper, I examine these prominent calls against using SSAs and argue that such calls do not withstand scrutiny. I then identify several types of mechanisms leading to slippery slopes in real‐life contexts to demonstrate that both the strength of SSAs and the justifiability of using SSAs are best assessed on a case‐by‐case basis. This result does not exempt the proponents of SSAs from the task of vindicating their use of SSAs. However, if correct, it undermines the often‐made claim that people should avoid using SSAs altogether.
Impact of graft‐versus‐host disease and graft‐versus‐leukemia effect based on minimal residual disease in Philadelphia chromosome‐positive acute lymphoblastic leukemia
Authors: Akahoshi Yu , Igarashi Aiko , Fukuda Takahiro , Uchida Naoyuki , Tanaka Masatsugu , Ozawa Yukiyasu , Kanda Yoshinobu , Onizuka Makoto , Ichinohe Tatsuo , Tanaka Junji , Atsuta Yoshiko , Kako Shinichi ,   the Adult Acute Lymphoblastic Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation
Published: March 2020

SummaryThe impacts of graft‐versus‐host disease (GVHD) and graft‐versus‐leukemia (GVL) effect might differ depending on minimal residual disease (MRD). Therefore, we examined 1,022 recipients who underwent their first allogeneic hematopoietic stem cell transplantation (HSCT) for Philadelphia chromosome‐positive acute lymphoblastic leukemia (Ph‐positive ALL) in first complete remission. MRD status at HSCT was negative in 791 (77·4%) and positive in 231 (22·6%). The impact of GVHD as a time‐dependent covariate on transplant outcomes were analyzed while adjusting for other possible variables. Mild acute GVHD [hazard ratio (HR), 0·90; 95% confidence interval (CI), 0·70–1·16; P = 0·901] and chronic GVHD (HR, 0·82, 95% CI, 0·58–1·14; P = 0·238) were not significantly associated with overall mortality, whereas severe acute GVHD (HR, 2·26, 95% CI, 1·64–3·11; P < 0·001) resulted in inferior overall survival due to high non‐relapse mortality. Moreover, even in the subgroup analyses stratified according to MRD status, acute and chronic GVHD were not significantly associated with better overall survival. Therefore, less intensive GVHD prophylaxis to achieve a GVL effect is not recommended for Ph‐positive ALL.
The combination of size‐based separation and selection‐free technology provides higher circulating tumour cells detection sensitivity than either method alone in patients with metastatic prostate cancer
Authors: Dong Liang , Zhang Zhongyuan , Smith Kimberly , Kuczler Morgan D. , Reyes Diane , Amend Sarah R. , Cho Yoon‐Kyoung , Xue Wei , Pienta Kenneth J. 
Published: March 2020

ObjectiveTo investigate the circulating tumour cells (CTCs) capture abilities of two technologies that are not dependent on cell‐surface marker expression: a selection‐free platform [AccuCyte®‐CyteFinder® system (Rarecyte)] and a size‐based platform [fluid‐assisted separation technology (FAST)]. In addition, the combination of the two systems to more completely assess CTCs was investigated.Patients and methodsIn all, 28 patients with metastatic prostate cancer were included. Two 6 mL peripheral blood samples were taken from each patient at the same time‐point. The samples were then subjected to the two different technology platforms in parallel. An additional group of samples was acquired by applying the waste chamber material from the FAST‐group tests (flow‐through that goes through the FAST filter membrane) to the Rarecyte system for the detection any CTCs that were not captured by FAST.ResultsThe three groups had significantly different putative CTC‐positive tests, with positive rates of 29% for Rarecyte, 57% for FAST, and 79% for the combination. We also assessed CTC phenotype: 56.6% of the CTCs were cytokeratin (CK)+/epithelial cell adhesion molecule (EpCAM)−, 3.1% were CK−/EpCAM+, and 40.3% were CK+/EPCAM+. The captured CTCs diameter ranged from 5.2 to 16.9 µm. The mean CTC size from the FAST waste chamber was significantly smaller. The diameters for each of the phenotypic groups were significantly different.ConclusionsThese data highlight disparities in the positive rates and enumerated CTC numbers detected by the two techniques. Notably, the combination of the two technologies resulted in the highest CTC‐capture rates. Smaller CTCs were more likely to be missed by the FAST as they passed through the filter system. Sizes of CTCs varied with different cell surface marker phenotypes.
Experimenting with public sector innovation: Revisiting Gow for the digital era
Authors: Doberstein Carey , Charbonneau Étienne 
Published: March 2020

AbstractIn 1988, James Iain Gow surveyed public servants across Canada on how they access and utilize research from various sources and how that is linked to policy innovation. He documented this research in his book Learning from Others (1994). Thirty years later, we replicate selected parts of the original survey conducted by Gow, but also add an experimental dimension that tests how subjects respond to public service innovations from around the world. We randomly alter key features of those innovations to examine if public servants reveal patterns in the way they process these innovations and make judgements about their suitability or promise.
Co-occurrence of IgE and IgG autoantibodies in patients with chronic spontaneous urticaria
Authors: Asero R , Marzano A V , Ferrucci S , Lorini M , Carbonelli V , Cugno M 
Published: March 2020

Summary
Chronic spontaneous urticaria (CSU) pathogenesis shows a complex and still unclear interplay between immunoglobulin (Ig)G- and IgE-mediated autoimmunity, leading to mast cell and basophil degranulation and wheal formation. The objective of this study was to evaluate at the same time IgE- and IgG-reactivity to well recognized and recently reported autoantigens in CSU patients, and to assess the effects of such reactivity on response to the anti-IgE monoclonal antibody omalizumab. Twenty CSU patients underwent omalizumab treatment. Urticaria activity score 7 (UAS7) was recorded at baseline and at different drug administration time-points for categorizing early-, late- or non-responders. At baseline, sera from the 20 patients and from 20 controls were tested for IgE and IgG autoantibodies to high- and low-affinity IgE receptors (FcεRI and FcεRII), tissue factor (TF) and thyroglobulin (TG) by immunoenzymatic methods. Antibody levels were compared with those of controls and analysed according to response. Eighteen patients were omalizumab responders (11 early and seven late), while two were non-responders. More than 50% of patients had contemporary IgE and IgG to at least to one of the four different autoantigens. Late responders showed higher levels of both anti-TF IgE and IgG than early responders (P= 0·011 and P= 0·035, respectively). Twenty-five per cent of patients had levels of anti-FcεRI IgE, exceeding the upper normal limit, suggesting that it could be a novel auto-allergen in CSU. In CSU, there is an autoimmune milieu characterized by the co-existence of IgE and IgG autoantibodies to the same antigen/allergen, particularly in late responders to omalizumab, possibly explaining the slower response.
Subacute cutaneous lupus erythematosus with positive anti‐Ro antibodies following palbociclib and letrozole treatment: A case report and literature review
Authors: Russell‐Goldman Eleanor , Nazarian Rosalynn M. 
Published: March 2020

AbstractDrug‐induced subacute cutaneous lupus erythematosus (DI‐SCLE) is an uncommon but well‐described phenomenon, most often seen in association with antihypertensives and antifungal medications. In recent years, rare reports of DI‐SCLE have been described in patients being treated with targeted therapies. Herein, we describe a case of DI‐SCLE in association with palbociclib and letrozole treatment for metastatic breast cancer. This report is the first known case of DI‐SCLE with positive anti‐Ro antibodies in this setting. We also summarize the literature describing DI‐SCLE in association with targeted therapies to date and its possible association with dysregulation of the vascular endothelial growth factor pathway.
Clinical validity of self‐rated oral health among New Zealand nursing home residents
Authors: Lundbeck Heather J. , Smith Moira B. , Thomson William M. 
Published: March 2020

AbstractObjectivesTo investigate the clinical validity of self‐rated oral health among older New Zealanders in aged residential care.Material and methodsA national survey of oral health in aged residential care was carried out throughout New Zealand. Self‐rated oral health was measured using Locker's global item and clinical examinations carried out by calibrated examiners. Analyses used survey weights.ResultsConsistent gradients were observed across the self‐rated oral health categories in the mean number of decayed teeth (whether coronal or root surface caries), mean number of filled teeth (albeit in the opposite direction), and in the mean number of fillings needed. Consistent gradients were also seen in the same categories when comparing the current oral health status to their oral health status a year previous. No gradients in periodontal status were apparent.ConclusionsThe older population in aged residential care can validly self‐rate their oral health, although further investigation of periodontal status is warranted.