bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adapting Public Spaces to the Wellness Needs of the Local Community
Authors: Švagždienė Biruta , Vaseris Vilius 
Published: June 2020

Research problem and relevance. With continuously expanding cities, less space is left for public, open areas. The urban planning is performed with regard to urbanistic elements, however, public spaces do not receive enough attention and creative potential (Piekienė, 2015). Individual’s and state’s political concept of public space changes by virtue of the premise of physical rationality and equality, moral values and the role of nature in modern cities. It is now defined as an urban structure, rather than a physical form of space, which meets not just the physiological needs of the individual, but also the general values of the community. The focus is on the moral, social, cultural details and their combination with physiological needs of an individual. Lately, people have become increasingly concerned about their living or recreational environment, necessity and importance of taking care of their health is no longer in doubt. Therefore, M. Burinskienė (2003) notes the aim to create right conditions that meet the interests of different people in various cities. Thus, in order to create sustainable balance between social, economic and environmental aspects, apart from the development of the physical infrastructure of the city, other aspects should be in focus (Čiegis, Žalevičienė, 2012). Analysis of application of public spaces has revealed that there are many scientific articles about the public spaces and related issues, however, opinions, criticism or discussions on this topic go in the same direction – public spaces are considered as isolated objects, rather than one, closely related system.The aim of the research was to assess the circumstances of adapting public spaces to the wellness needs of the local community on the case of Kaunas. The object of the research was the adaptation of public spaces to the needs of the local community. Research methodology. The qualitative research was conducted and a semi-structured interview was selected to collect the data using a convenience sampling method: several interviewees were selected from the researchers’ academic environment (university) upon recommendations. The method based on geographical definition was followed when selecting the interviewees. All interviewees study, work and live in Kaunas.Results. The study revealed that the adaptation and accessibility of public spaces for the wellness needs of the local community was still insufficient. Public spaces were not yet directed to even distribution and adaptability and their formation process did not fully satisfy sustainability criteria.Keywords: public space, leisure, community, wellness, adaption.
Non-drug treatment of non-alcoholic fatty liver disease: evaluation of effectiveness with ultrasound steatometry
Authors: Venidiktova D. Yu. , Borsukov A. V. 
Published: June 2020

Objective. Evaluation of the effectiveness of non-drug treatment in patients with non-alcoholic fatty liver disease using the method of quantitative ultrasound steatometry.Material and methods. We examined 118 patients aged 18–75 years, including 52 (44 %) men and 66 (56 %) women using a single diagnostic algorithm of four stages: questioning and collecting complaints, assessing the quality of life, clinical examination, non-invasive bioimpedansometry, followed by assessment of fat mass index, ultrasound examination of the liver in the B-mode, quantitative ultrasound steatometry by evaluating the attenuation coefficient of the ultrasonic wave. Individual non-drug therapy is prescribed to patients in the form of an individual program of therapeutic nutrition and physical activity. A dynamic assessment of the decrease in the proportion of adipose tissue and the severity of fatty liver infiltration was carried out at points of 6, 12, 18, 24 months. A liver biopsy followed by histological analysis on an SAF scale was performed in 32 patients.Results. To assess the effectiveness of non-drug treatment in patients, a tendency of reducing the proportion of fat content and the severity of fatty infiltration in the liver was observed. All patients were divided into two groups according to their level of compliance with the prescribed treatment. Decrease in the proportion of adipose tissue in patients with a high level of compliance – up to 76.2 %, in patients with a low level of compliance – up to 89.1 % of the initial values. Decrease in fatty liver infiltration in patients with a high level of compliance – up to 80.2 %, in patients with a low level of compliance – up to 92.1 % of the initial one.Conclusion. Ultrasound steatometry is an informative method for non-alcoholic fatty liver disease screening. The correlation of quantitative ultrasound diagnostics data for steatosis with a biopsy at stage S0 corresponds to r = 0.85; at stage S1 r = 0.72, at S2 r = 0.73, at stage S3 corresponds to r = 0.84, which indicates the high informativity of this method.
Reproductive health of women with fat metabolism disorders
Authors: Vedzizheva E. R. , Kuznetsova I. V. 
Published: June 2020

Objective: to assess the reproductive health features of women with fat metabolism disorders and the safety of using combined oral contraception in them.Materials and methods. 150 women of childbearing age (mean age 29.8 ± 4.7 years) were examined, which were divided into three groups depending on the type of impaired fat metabolism: the first group included patients with obesity and dyslipidemia (n = 50); the second group – women with obesity without dyslipidemia (n = 46); the third group – patients with a normal body mass index and dyslipidemia (n = 54). All patients underwent clinical and laboratory examination with the assessment of biochemical, metabolic and hormonal blood parameters. At the second stage of the study, the safety assessment of the use of combined oral contraceptive with chlormadinone acetate (COC–CMA) in women in need of pregnancy protection was performed.Results. Women with fat metabolism disorders have a high prevalence of menstrual irregularities. The most commonly detected were polycystic ovary syndrome (PCOS), phenotypes A, C, D. In the absence of PCOS in obese women or patients with dyslipidemia at normal weight, the formation of endocrine pathology was observed, associated with hyperandrogenemia or a tendency to hypogonadotropic hypogonadism. Patients with obesity and dyslipidemia had the worst fertility profile and high prevalence of infertility and miscarriage. Taking COC–CMA did not have a significant effect on fat metabolism.Conclusion. Dyslipidemia and obesity are independent factors in reproductive health problems. Clinical portraits of gynecological endocrine pathology in patients with obesity, dyslipidemia and their combination are different. The assessment of carbohydrate and fat metabolism should be considered one of the important components of the examination of patients with menstrual dysfunction or impaired fertility. COC–CMA can be considered the drug of choice for contraception in women with impaired fat metabolism.
Effectiveness of combined drug containing calcium and vitamin D in treatment of primary dysmenorrhea in adolescent girls
Authors: Gevorgyan A. P. , Adamyan L. V. , Arslanyan K. N. , Ivanova G. I. 
Published: June 2020

Objective.To increase the effectiveness of early diagnosis and to develop a differentiated approach to the treatment of adolescent girls with primary dysmenorrhea (PD).Material and methods.The study was conducted on 100 adolescent girls aged 15 to 17 years, diagnosed with primary dysmenorrhea, who were initially divided into study and control groups depending on the presence or absence of dysplasia of connective tissue (DCT). Then, to compare the two proposed treatment regimens, each group was divided by randomization into two subgroups. Basic therapy included drug NSAIDs and vitamin-mineral complex with a content of calcium 1 000 mg and vitamin D3800 IU per day. The second scheme: the basic treatment was added to the drug L-carnitine 800 mg, affecting collagen formation. Self-assessment of menstrual pain was performed using McGill’s pain questionnaire. The levels of free hydroxyproline, MMP-2 and -9, tumor necrosis factor α, serum magnesium, autoantibodies IgG to cardiolipin, antinuclear antibodies were determined.Results.In adolescent girls with DCT, the level of free blood hydroxyproline was almost two times higher than in patients with PD without DCT (276.78 ± 117.10 and 142.64 ± 90.40 ng/ml respectively to the groups; p < 0.05). In both groups, no cases of magnesium deficiency in the blood were detected. In the analysis of biochemical parameters in serum after treatment, in all groups all blood parameters significantly improved-free hydroxyproline decreased on average in 2.5 times, MMP in 3.0 times, TNF-α in 2.0 times, MMP-9 increased in 4.0 times and autoantibodies IgG to cardiolipin decreased on average in 4.0 times (p < 0.05).Conclusions.The proposed PD therapy with NSAIDs and vitamin-mineral complex, including calcium and vitamin D, the effectiveness of which is confirmed not only by clinical data, but also by biochemical studies, it is advisable to appoint patients with PD, including those with signs of DST. The results of our own research and literature data allow us to recommend prophylactic intake of vitamin and mineral complex containing calcium and vitamin D to adolescent girls suffering from PD, to improve the quality of life, reduce the drug load and prevent reproductive disorders in the future.
Intensity of lamella growth as morphofunctional feature of human platelets
Authors: Makarov M. S. 
Published: June 2020

Aim.To study morphofunctional properties of platelet lamella′s forming in donors and patients with thrombotic disorders.Materials and methods.We studied platelets of blood donors, patients with deep venous thrombosis, burned patients with thrombotic disorders. Morphofunctional analysis was performed, using original method, based on cell vital staining.Results. In patients with deep venous thrombosis morphofunctional platelet value was enhanced, in burned patients with thrombotic disorders platelet integrity was low. After 10–15 minutes of adhesion on glass spreading platelets maintained 3 subpopulations: cells without lamella, able to fluent granule efflux (1th type); cell with lamellipodias (2th type); cells with wide lamella, covering cell perimeter (3th type). In donors′ blood most of spreading platelets formed lamella at 1–2 hours, in patients with deep venous thrombosis this process was noticeably accelerated, estimating 30–35 minutes, what is more, spreading platelets viewed both intensive lamella′s growth and rapid degranulation of cells without lamella, followed by aggregation on the glass. Burned patients had significant decay of platelet adhesion, lamella formation was low-identified – less than 20 % of spread platelets formed lamellipodias. Among blood donors one could notice heterogeneous level of platelets, capable to rapid granules′ release during contact with adhesive substrate.Conclusion.The lack of lamella forming may occur both at low and high morphofunctional platelet rate. During deep venous thrombosis lamella′s growth velocity was noticeably increased. Among spreading platelets with granules one could find subpopulation of cells, capable to rapid granules′ release in norm and pathology.
Specificity of dermatological adverse events of BCR-ABL tyrosine kinase inhibitors and their effect on quality of life of patients with chronic myeloid leukemia
Authors: Shatokhina E. A. , Turkina A. G. , Chelysheva E. Yu. , Shukhov O. A. , Petrova A. N. , Kovrigina A. M. , Kruglova L. S. , Ranenko E. V. , Nosikova P. G. 
Published: June 2020

Introduction. BCR-ABL tyrosine kinase inhibitors are currently used to successfully treat chronic myeloid leukemia (CML). Drug therapy is carried out in a continuous daily mode throughout the patient’s life. Treatment with this group of drugs is associated with specific dermatological adverse events (dAE), which can lead to a change in the regimen of effective, vital therapy for CML patients.Purpose. To study the characteristics of dermatological adverse events, the severity and influence on the quality of life of BCR-ABL tyrosine kinase inhibitors.Patients and methods. The observational study included 93 patients. The clinical manifestations of dAE, their severity were evaluated, their photographs and pathomorphological studies of skin biopsy samples were performed, cases of dose reduction or drug withdrawal due to dAE were recorded. The quality of life of patients with dAE was determined based on the assessment of the dermatological index of quality of life.Results. Imatinib therapy was accompanied by a maculopapular rash in 43.3 % of patients, nilotinib caused follicular keratosis in 12.9 % of patients. In 3.2 % of patients, dasatinib caused hyperpigmentation, in 2.2 % of patients lichenoid rashes of the II degree occurred during treatment with bosutinib. Ponatinib treatment was followed by dAE in 9.7 % of patients. All dAE have an impact on the quality of life of patients, but the maculopapular rash and dyskeratotic changes are most pronounced. In a pathomorphological study, these dAE have specific features corresponding to immuno-mediated dermatitis.Conclusions. The most frequent and pronounced dAE that significantly affect the quality of life of patients with CML are a maculopapular rash and dyskeratotic skin changes: psoriasiform and lichenoid dermatitis. Clinical and pathomorphological characteristics of skin reactions make it possible in the future to determine effective methods of supportive therapy for dAE.
Analysis of pharmacotherapy of patients with acute coronary syndrome at pre-hospital stage
Authors: Eryomina E. Yu. , Sveshnikov K. A. , Lityushkina M. I. 
Published: June 2020

A patient with acute coronary syndrome requires not only urgent hospitalization, continuous medical observation, but also medical and diagnostic measures that meet standard standards.Purpose of the study.Аnalysis of the management of patients with acute coronary syndrome with ST segments elevation in the prehospital phase.Materials and methods.Analysis of emergency medical care patients with acute coronary syndrome with ST-segment elevation in 2017. In the study group, men (126 people) and women (119 people).Results.The average time of arrival of the team is 14 minutes, the total time of patient care is 28.9 minutes (excluding time for delivery to the hospital). The time from the call to the moment of delivery to the emergency department is 53 minutes. Analysis of drug therapy revealed that the frequency of nitrates was 88.8 %, antiplatelet therapy – 88.2 %, narcotic analgesics – 82.3 %, anticoagulants – 67.3 %, β-blockers – 18.7 %, oxygen therapy – 36.3 %, antiarrhythmic drugs – 6.4 %, fibrinolytic therapy was performed in 54.3 % of patients.Conclusions.А patient with acute coronary syndrome with ST elevation segments in the prehospital hospital provided sufficient medical care in accordance with clinical guidelines. A low percentage of thrombolytic therapy is associated with the presence of absolute contraindications for the patient.
Heterotopias e trajetividades: lugares para as diferenças nas subjetividades nômades
Authors: Carvalho Alexandre Filordi de 
Published: June 2020

A partir de duas experiências cinematográficas, Omar e The giver (O doador de memória) como agenciamentos de signos da arte, busca-se, ao longo do texto, explorar a ideia de que heterotopias e trajetividades são noções importantes para se pensarem as diferenças no sentido de experiências de subjetividades nômades. Para tanto, é preciso combater a máquina de produção de subjetividades sedentárias. Dessa maneira, em um primeiro momento, desde uma hipótese proustiana, intenta-se entender o que são experiências com as heterotopias e as trajetividades, sobretudo a partir do filme Omar. Em segundo lugar, a partir de uma questão extraída do filme The giver, explora-se como o campo problematizador das diferenças pode ser afirmado entre a confrontação da máquina de produção de subjetividade sedentária e a máquina de produção de subjetividade nômade.
Boca de lixo: o outro, o nome e o encontro
Authors: Ribetto Anelice , Filé Valter 
Published: June 2020

Este ensaio é um esforço para pensar o documentário Boca de lixo, de Eduardo Coutinho, como uma expressão estética que nos permite abordar os sentidos e os efeitos provocados por algumas das suas passagens e ampliar um dos conceitos com os quais trabalhamos há um tempo: o encontro. O encontro como espaço de conversação e como contorno metodológico possível para as pesquisas que interpelam a diferença e as relações de alteridade como questões para o campo da Educação. Para isso, ensaiamos algumas cenas de sentido. O Outro: o que há nele? e A pergunta e seus efeitos em nós: cenas que se ampliam a partir da abertura de um campo problemático e do conceito de encontro e suas condições de possibilidade para que a diferença seja mantida na sua radicalidade.
Review Named Entity Recognition dengan Menggunakan Machine Learning
Authors: Rachmad Dwi Swasono 
Published: June 2020

NER atau Named Entity Recognition yang sering dikenal sebagai salah satu komponen utama dari sistem pertanyaan jawaban. NER memiliki cara tradisional yang selanjutkan dikembangkan sebagai salah satu komponen untuk mendapatkan informasi dengan mengekstraksi kata dan terdapat teknik yang dapat difokuskan pada tahap terakhir. Pada artikel ini dapat diketahui dengan melakukan beberapa pendekatan telah digunakan oleh beberapa peneliti dalam meneliti fungsi NER sebagai ekstraksi informasi kata. Name Entity Recognition atau NER pada berbagai penerapan yang telah dilakukan penelitiannya. NER memiliki fungsi sebagai ekstrasi dari kata yang dapat memberikan informasi terkait kalimat atau kata-kata. Berdasarkan pada penelitian dapat diketahui terdapat beberapa masalah pada sistem penjawab pertanyaan yang masih merupakan bidang yang menarik untuk dilakukan pada bahasa Indonesia, Bahasa India khususnya Telugu, bahasa Arab, dan NER pada kelas nama, lokasi, organisasi, dan lainnya menghasilkan hasil yang baik dan akurasi tinggi. Namun NER yang tidak dilakukan pada kelas lokasi seperti tanggal, waktu, dan tempat serta tidak menggunakan data yang besar untuk ekstrasi dalam NER. Dalam hal ini, NER akan dimanfaatkan untuk machine learning yang lebih baik untuk mengenal berbagai kata atau elemen eksraksi dari suatu kata.
Fetal Doppler Simulator Based on Arduino
Authors: Alfina Nadhirotussolikah  , Andjar Pudji  , Muhammad Ridha Mak'ruf  
Published: June 2020

Heart rate of the fetal is the main indicator of the fetal life in the womb. Monitoring fetal heart rate can’t be done, so a tool is needed to monitoring fetal heart rate. Fetal heart rate can be monitored with fetal doppler. To test the accuracy of Fetal Doppler, a calibration is needed with the Fetal Doppler Simulator. This tool will simulate the fetal heart rate with a BPM value that can be adjusted according to the settings on the device. This module using Arduino as the brain system. On the module there is a selection of BPM from 60 to 240 BPM with an increase of 30 BPM displayed on 2x16 character LCDs. Based on BPM measurement 6 times using Fetal Doppler, the measurement error in a BPM of 60 to BPM 210 is 0%, while at BPM 240 an error is 0.2%. This module has been compared with the standard devices (Fetal Simulator Brand Fluke Biomedical Ps320), the results of the comparison modules with the comparison tool has the same error value in 240 BPM is 0.2% and in BPM 210 there is a difference in the result of module Fetal Doppler reading of 210 BPM while in the comparison tool is 209 BPM. Of the measurement data and analysis, it can be concluded that the tool can work and the tool has the same accuracy as the standard device.
ÇİFT KÖPRÜLÜ ASKI TİP KREN SİSTEMLERİNİN SONLU ELEMANLAR METODU İLE MODAL ANALİZİ
Authors: YILDIRIM Şahin , ESİM Emir 
Published: June 2020

Doğal frekanslar cisimlerin kütle ve esnekliğine
bağlı olarak belirlenen bir parametredir.
Kren sistem elemanların hepsi birbiri ile temasta olmasından dolayı bir
bütün olarak tasarlanıp frekansların belirlenmesi gerekmektedir. Bu nedenle
kren sisteminin çalışma şartlarına göre üzerinde araba bulunması ve sistemde
yapının yük ile hareket etmesi sebebi ile kren sistemi bir bütün olarak
modellenmiştir. Ayrıca kren sistemlerinde köprü grubunun hareket ettiği
taşıyıcı çerçevelerde dikkate alınarak modal analizler Sonlu Elamanlar Metodu
(SEM) ile yapılmıştır. Köprü grubu, kaldırma grubu ve yük ile tasarlanan kren
sisteminde; araba grubunun ve yükün köprü başında ve ortasında olması
durumlarına göre de analizler yapılmıştır. Belirtilen şartlara göre doğal
frekans ve mod şekilleri elde edilerek, karşılaştırmalar yapılmış ve tasarım özelliklerinin sonuçlar üzerindeki etkileri üzerinde durulmuştur.
Extending UML Use Case Diagrams to Represent Non-Interactive Functional Requirements
Authors: Iqbal Saqib , Al-Azzoni Issam , Allen Gary , Ullah Khan Hikmat 
Published: June 2020

Background: The comprehensive representation of functional requirements is a crucial activity in the analysis phase of the software development life cycle. Representation of a complete set of functional requirements helps in tracing business goals effectively throughout the development life cycle. Use case modelling is one of the most widely-used methods to represent and document functional requirements of the system. Practitioners exploit use case modelling to represent interactive functional requirements of the system while overlooking some of the non-interactive functional requirements. The non-interactive functional requirements are the ones which are performed by the system without an initiation by the user, for instance, notifying something to the user or creating an internal backup.
Aim: This paper addresses the representation of non-interactive requirements along with interactive ones (use cases) in one model. This paper calls such requirements `operation cases’ and proposes a new set of graphical and textual notations to represent them.
Method: The proposed notations have been applied on a case study and have also been empirically evaluated to demonstrate the effectiveness of the new notations in capturing non-interactive functional requirements.
Results and Conclusion: The results of the evaluation indicate that the representation of operation cases helps in documenting a complete set of functional requirements, which ultimately results in a comprehensive translation of requirements into design.