bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing periodontal health and the british society of periodontology implementation of the new classification of periodontal diseases 2017
Authors: Milward Mike R , Roberts Anthony 
Published: November 2019

Periodontal disease is a highly prevalent, chronic, inflammatory condition which is a major contributor to tooth loss and poor oral health-related quality of life. For the vast majority of patients, the disease is entirely preventable/manageable often aided by input from dental health professionals. As dental health professionals, understanding the periodontal disease process, the risk factors associated with it, standardized ways of detecting, diagnosing and monitoring the disease, along with the special tests needed to aid this process are essential skills for successful disease management. This article summarizes the need for assessing periodontal disease including key aspects of detection, a brief history of periodontal disease classification and the new classification. The paper goes on to discuss the British Society of Periodontology implementation plan of new classification and how this can be utilized for use in general dental practice. CPD/Clinical Relevance: This paper introduces the practitioner to the 2017 Classification of Periodontal Disease along with how this is implemented in general dental practice. The paper provides useful cases for practice as well as flowcharts to aid diagnosis.
Assessment and management of endo-periodontal lesions
Authors: Hoyle Philippa , Tank Manoj , Modarres-Simmons Somayeh , Storey Claire Annabel 
Published: November 2019

Endo-periodontal lesions present a number of challenges for clinicians. These include understanding their underlying aetiology, forming an accurate diagnosis and suitable prognosis and subsequently formulating an effective treatment strategy. This article aims to provide a summary of the literature available in the areas highlighted above, with particular reference to the recent joint American Academy of Periodontology and European Federation of Periodontology (AAP/EFP) world workshop for classification of periodontal and peri-implant diseases. CPD/Clinical Relevance: This paper outlines important aspects a clinician must consider, including anatomy, a systematic methodology for assessment and introduction of the new classification of periodontal diseases in diagnosis. Prognosis and formulation of appropriate management strategies are explored.
Prevalence of pressure ulcers in long-term care: a global review
Authors: Anthony Denis , Alosoumi Dalyal , Safari Reza 
Published: November 2019

Objective:To identify and update the prevalence and incidence of pressure ulcers (PUs) in several countries, in people with long-term conditions resident in care homes or nursing homes.Methods:We followed the PRISMA guideline for systematic reviews. However, due to funding constraints we do not claim this review to be systematic but it is a narrative review informed by PRISMA. Medline, Embase and CINHAL were searched for observational studies reporting incidence or prevalence data. Data reported relevant head-to-toe examination of PUs in residence in care or nursing homes. Internal and external validity of the included studies were assessed using the checklist devised by Hoy et al.1Results:Inclusion criteria was met by 17 studies and included in the study. Some studies gave a full breakdown by category, some only gave overall figures, and others excluded category I PUs. However, within those constraints certain patterns are clear. Prevalence rates varied from 3.4–32.4%. Large differences in prevalence in different countries were not explained by methodological differences. While some countries, such as Germany, the Netherlands and the US had robust data, other countries, such as the UK, had none.Conclusion:PUs are a common problem in long-term care. However, there are substantial differences between countries and many countries have no published data.
Use of a monofilament debridement pad in the treatment of acne vulgaris
Authors: Eberlein Thomas , Wiegand Cornelia , Andriessen Anneke , Roes Claas , Abel Martin 
Published: November 2019

Objective: Acne vulgaris (acne) presents with increased oil-sebum secretion and subsequent formation of comedones, papules, pustules and nodules. Skin cleansing is part of the daily routine to improve skin condition. A monofilament debridement pad has shown to be effective when used for wound debridement and skin cleansing in dermatological conditions. The pad may offer benefits when used for acne affected skin. Methods: The in vitro cleansing capacity of the monofilament fibre pad was analysed and compared with commercially available cosmetic pads. For this purpose, a sebum model consisting of glass plates coated with an oil-red-stained layer of artificial sebum was used. To gain clinical experience a case series evaluated cleansing efficacy of the monofilament debridement pad in combination with polyhexanide and sodium-hypochlorite based solutions. Over a period of four months, seven individuals suffering from retentive moderate facial acne who visited the dermatology clinic for their acne used the pad as necessary, ranging from twice weekly to daily, dependent on the sensitivity of the patient's skin condition. Results: The in vitro study exhibited a significantly better cleansing efficacy of the monofilament debridement pad compared with the cosmetic pads. After single use of the pad subject scores on sebum reduction revealed excellent/very good in 42.9% and acceptable in 57.1% of cases. After repeated use of the monofilament pads scores on sebum reduction of excellent/very good were given in 85.7% and acceptable in 14.3% of cases. Subject scored handling of the pad and comfort during use also received favourable ratings. Conclusion: These initial results show the potential of the monofilament debridement pad for cleansing of acne-prone and acne affected skin. More robust studies are needed to confirm these results.
Spray Application Efficiency from a Multi-Rotor Unmanned Aerial Vehicle Configured for Aerial Pesticide Application
Authors: Richardson Brian , Rolando Carol A. , Kimberley Mark  O. , Strand Tara  M. 
Published: November 2019

HighlightsThe swath pattern was measured from an Agras MG-1 UAV spraying fine and extra-coarse droplet spectra.The recommended lane separation of 3.6 m did not differ for the two droplet size classes tested in this study.The applied spray deposited within the swath was higher with extra-coarse (&gt;90%) than with fine (73%) droplets.There was potential for substantial downwind drift with fine droplets, even when flying close to the ground at low speed.Abstract. While there is increasing interest in the use of small, multi-rotor UAVs for application of agrichemicals, there is also uncertainty about their performance. Consequently, the purpose of this study was to quantify the performance of an Agras MG-1 with modified nozzle positions that, at the time of writing, was being used for commercial spraying in New Zealand. The approach was to release spray from the UAV along a single 50 m line. Spray deposits were measured using horizontal collectors placed on the ground in three 15 m transects centered on, and perpendicular to, the flight line. Airborne deposits were measured with a 10 m mast that supported spherical samplers at 1 m vertical intervals. Analysis of deposition data was undertaken to quantify factors influencing overall swath pattern variability, lane separation associated with a coefficient of variation (CV) of deposition of 30%, and spray application efficiency, which is the proportion of applied spray deposited within the swath. For two droplet size classes (extra-coarse and fine), the lane separation associated with a CV of 30% was about 3.6 m, with no significant effect of droplet size. This is a surprising result and may reflect the relatively small range of environmental conditions experienced during the field tests, including wind speed, which was relatively low for all tests. We speculate that this result may also be a consequence of the strong downwash. The swath width was positively correlated with wind speed. Spray efficiency was shown to be high (&gt;90%) for the extra-coarse droplets but dropped significantly (73%) with the fine droplet spectrum. Combining in-swath deposition with the amount of airborne spray sampled in a 10 m vertical profile close to the edge of the swath accounted for 98.0% of the spray released with the extra-coarse spectrum but only 88.6% of the spray with the fine droplet spectrum. These results highlight that even with UAVs flying relatively close to the ground at a low forward speed, there is potential for substantial drift downwind of the swath when using smaller droplet size classes. Overall, the swath pattern was reasonably consistent across the two droplet size classes and for the narrow range of operational and meteorological conditions tested. Keywords: Aerial spraying, Pesticides, Spray application efficiency, Spray deposition, Swath pattern, UAV, Unmanned aerial vehicle.
Exeter Book Riddle 95: ‘The Sun’, a New Solution
Authors: Bitterli Dieter 
Published: November 2019

Abstract
Elusive and fraught with textual difficulties, Riddle 95, the ‘last’ of the Old English verse riddles preserved in the tenth-century Exeter Book, has long baffled modern readers as one of a handful of thorny items in the collection that have so far defied solution. ‘Book’ is the answer that has found most acceptance with critics in the past, yet the speaking subject of Riddle 95 is unlike anything described in those items of the collection that actually deal with writing and the tools of the monastic scriptorium. Rather, the linguistic and thematic parallels between Riddle 95 on the one hand, and the cosmological riddles and poems in the Exeter Book on the other, strongly suggest that the subject of Riddle 95 is the sun, a frequent topic of early medieval enigmatography. The poem obliquely relates how the rising sun installs itself in the sky to shed its welcome light upon the earth before it sets and vanishes from sight, completing its daily orbit along unknown paths. The main clues helping to secure the solution ‘sun’ are based upon what was known in Anglo-Saxon England about the solar course and the planetary motions, especially from the astronomical writings of Isidore of Seville and Bede. Further evidence is provided by several analogues in the Anglo-Latin riddle tradition, including the Enigmata of Aldhelm and his followers.
Solutions for Fractional Schrödinger Equation Involving Critical Exponent via Local Pohozaev Identities
Authors: Guo Yuxia , Liu Ting , Nie Jianjun 
Published: November 2019

Abstract
We consider the following fractional Schrödinger equation involving critical exponent:

{

(

-
Δ

)

s

⁢
u

+

V
⁢

(
y
)

⁢
u

=

u

2
s
*

-
1

in
⁢

ℝ
N

,

u
>
0

,

y
∈

ℝ
N

,

\left\{\begin{aligned} &\displaystyle(-\Delta)^{s}u+V(y)u=u^{2^{*}_{s}-1}&&% \displaystyle\text{in }\mathbb{R}^{N},\\ &\displaystyle u>0,&&\displaystyle y\in\mathbb{R}^{N},\end{aligned}\right.

where

N
≥
3

{N\geq 3}

and

2
s
*

=

2
⁢
N

N
-

2
⁢
s

{2^{*}_{s}=\frac{2N}{N-2s}}

is the critical Sobolev exponent. Under some suitable assumptions of the potential function

V
⁢

(
y
)

{V(y)}

, by using a finite-dimensional reduction method, combined with various local Pohazaev identities, we prove the existence of infinitely many solutions. Due to the nonlocality of the fractional Laplacian operator, we need to study the corresponding harmonic extension problem.
Crystal structure of chlorido-(η
5-pentamethylcyclopentadienyl)-((bis-pyrazol-1-yl)methane-κ2
N,N′) rhodium(III) hexafluorophosphate. (C17H23ClN4RhF6P)
Authors: Gichumbi Joel M. , Zamisa Sizwe J. , Friedrich Holger B. 
Published: November 2019

Abstract
C17H23ClN4RhF6P, monoclinic, P21/c (no. 14), a = 10.6954(2) Å, b = 15.3868(3) Å, c = 12.6130(2) Å, β = 90.5590(10)°, V = 2075.60(7) Å3, Z = 4, R
gt(F) = 0.0296, wR
ref(F
2) = 0.0727, T = 100(2) K.
The Irrigation Canal Stele of the Urartian King Argišti I Recently Discovered in Erciş/Salmanağa, North of Lake Van
Authors: Işık Kenan 
Published: November 2019

Abstract
This article presents a recently-found inscribed stele belonging to the Urartian king Argišti I (ca. 785/80–756 BC). The stele was erected to commemorate the inauguration of an irrigation channel running off the Dainalitini Stream (modern Deliçay), north of Lake Van in Eastern Turkey. The inscription on this stele is important, both for localizing the Dainalitini Stream mentioned in Urartian texts, as well as understanding sacrificial rituals in agricultural contexts.
High Velocity and Temperature Effects on the Bending Behavior of Nickel Nanowire: A Large-Scale Molecular Dynamics Simulation Study
Authors: Gupta Pradeep , Katakam Krishna Chaitanya , Yedla Natraj 
Published: November 2019

Abstract
We performed classical molecular dynamics (MD) simulation of bending of large-size nickel nanowire (NW) of size 28a (x-axis) by 284a (y-axis) by 28a (z-axis) comprising of 925,965 atoms (where a = 3.52 Å). Embedded atom method potential is used for modeling the interactions between nickel atoms. Bending studies have been carried out at temperatures in the range of 300 K–1,500 K. A rigid diamond tip is used to apply force on the NW at a velocity of 100 m/s along z-direction [0 0 −1]. The load time results show that as the temperature increases the yield load decreases as expected and is more significant at temperatures higher than 900 K. The structural studies are carried out by centro-symmetry parameter (CSP) and radial distribution function (RDF) analysis. The CSP analysis reveals the formation of stacking faults in the NW regions below the indenter tip, indicating localized plastic deformation. The RDF analysis reveals that with an increase in temperature the regions in the NW below the indenter tip become disordered. Dislocation extraction algorithm analysis carried out for understanding the plastic deformation mechanism reveals that the deformation mechanism is by slip by Shockley partial dislocations. We also observed twins in a few regions of the NW. The fracture features of the NW suggest ductile nature.
Comparative Analysis of Whole-Genome and Methylome Profiles of a Smooth and a Rough Mycobacterium abscessus Clinical Strain
Authors: Chhotaray Chiranjibi , Wang Shuai , Tan Yaoju , Ali Amjad , Shehroz Muhammad , Fang Cuiting , Liu Yang , Lu Zhili , Cai Xingshan , Hameed H M Adnan , Islam Md Mahmudul , Surineni Goverdhan , Tan Shouyong , Liu Jianxiong , Zhang Tianyu 
Published: November 2019

Abstract
Mycobacterium abscessus is a fast growing Mycobacterium species mainly causing skin and respiratory infections in human. M. abscessus is resistant to numerous drugs, which is a major challenge for the treatment. In this study, we have sequenced the genomes of two clinical M. abscessus strains having rough and smooth morphology, using the single molecule real-time and Illumina HiSeq sequencing technology. In addition, we reported the first comparative methylome profiles of a rough and a smooth M. abscessus clinical strains. The number of N4-methylcytosine (4mC) and N6-methyladenine (6mA) modified bases obtained from smooth phenotype were two-fold and 1.6 fold respectively higher than that of rough phenotype. We have also identified 4 distinct novel motifs in two clinical strains and genes encoding antibiotic-modifying/targeting enzymes and genes associated with intracellular survivability having different methylation patterns. To our knowledge, this is the first report about genome-wide methylation profiles of M. abscessus strains and identification of a natural linear plasmid (15 kb) in this critical pathogen harboring methylated bases. The pan-genome analysis of 25 M. abscessus strains including two clinical strains revealed an open pan genome comprises of 7596 gene clusters. Likewise, structural variation analysis revealed that the genome of rough phenotype strain contains more insertions and deletions than the smooth phenotype and that of the reference strain. A total of 391 single nucleotide variations responsible for the non-synonymous mutations were detected in clinical strains compared to the reference genome. The comparative genomic analysis elucidates the genome plasticity in this emerging pathogen. Furthermore, the detection of genome-wide methylation profiles of M. abscessus clinical strains may provide insight into the significant role of DNA methylation in pathogenicity and drug resistance in this opportunistic pathogen.
Kingella kingae and Osteoarticular Infections
Authors: Samara Eleftheria , Spyropoulou Vasiliki , Tabard-Fougère Anne , Merlini Laura , Valaikaite Raimonda , Dhouib Amira , Manzano Sergio , Juchler Céline , Dayer Romain , Ceroni Dimitri 
Published: November 2019

OBJECTIVES:
In this study, we aimed to contrast the bacteriologic epidemiology of osteoarticular infections (OAIs) between 2 patient groups in successive 10-year periods, before and after the extensive use of nucleic acid amplification assays in the diagnostic process.

METHODS:
Epidemiologic data and bacteriologic etiologies of all children presenting with OAIs on admission to our institution over 20 years (1997–2016) were assessed retrospectively. The population was divided into 2 cohorts, using the standardized use of polymerase chain reaction as the cutoff point (2007). The conventional cohort included children with OAIs mainly investigated by using classic cultures, whereas the molecular cohort referred to patients also investigated by using molecular assays.

RESULTS:
Kingella kingae was the most frequently isolated pathogen, responsible for 51% of OAIs, whereas other classic pathogens were responsible for 39.7% of cases in the molecular cohort. A statistically significant increase in the mean incidence of OAIs was observed, as was a decrease in the mean age at diagnosis after 2007. After 2007, the pathogen remained unidentified in 21.6% of OAIs in our pediatric population.

CONCLUSIONS:
Extensive use of nucleic acid amplification assays improved the detection of fastidious pathogens and has increased the observed incidence of OAI, especially in children aged between 6 and 48 months. We propose the incorporation of polymerase chain reaction assays into modern diagnostic algorithms for OAIs to better identify the bacteriologic etiology of OAIs.
Analysis of Differentially Expressed MicroRNAs and Circulating Tumor Cells as Predictive Biomarkers of Platinum Chemoresistance in Primary Ovarian Carcinomas: A Prospective Study
Authors: Lou Emil , Vogel Rachel I. , Hoostal Spencer , Wong Phillip , Grad Aaron , Monu Minnu , Łukaszewski Tomasz , Deshpande Jaai , Dickson Elizabeth L. , Klein Molly , Linden Michael A. , Subramanian Subbaya , Teoh Deanna , Geller Melissa A. 
Published: November 2019

Abstract

Lesson Learned
Circulating tumor cells, microRNA markers, or other biomarkers merit examination as part of correlative scientific analyses in prospective clinical trials.

Background
Platinum chemotherapy resistance occurs in approximately 25% of patients with ovarian carcinoma; however, no biomarkers of ovarian carcinoma chemoresistance have been validated. We performed a prospective trial designed to identify tumor-based predictive biomarkers of platinum resistance.

Methods
Tumor specimens were collected from 29 women with newly diagnosed histopathologically proven primary ovarian carcinoma. Of these, 23 women had specimens accessible for assessment and outcome data available regarding chemosensitive versus chemoresistance status via review of the medical record. Tumor slices were stained with antibodies against two microRNAs (miRNAs 29b and 199a) differentially expressed in chemoresistant ovarian cancer cell lines. Additionally, blood samples obtained at the time of diagnosis were analyzed for the presence of circulating tumor cells (CTCs).

Results
The average age of the patients was 64 years, and 82.6% had high-grade epithelial carcinomas. The baseline median CA-125 was 464 (range 32–2,782). No statistically significant differences were observed in miR29b or 199a expression in platinum-resistant/refractory versus platinum-sensitive tumors. Furthermore, the presence of CTCs was not found to be statistically significantly predictive of eventual platinum resistance.

Conclusion
Our analysis showed no differences in miR29b and 199a expression, and differences in baseline CTCs in women with newly diagnosed ovarian tumors were not statistically significant.
Quality of life of patients with rectal cancer after surgical treatment
Authors: Medvednikov A. A. , Shelekhov A. V. , Dvornichenko V. V. , Plenkin S. M. , Radostev S. I. 
Published: November 2019

Objective: to analyze functional surgical outcomes in patients with distal rectal cancer and their quality of life at different time-points postoperatively.Materials and methods. This retrospective study included all patients with rectal cancer that underwent either abdominoanal resection of the rectum (with their sigmoid colon brought down into the anal canal) or low intraabdominal resection of the rectum with the formation of a mechanical coloanal anastomosis in Irkutsk Regional Oncology Dispensary between 1999 and 2012. Study participants were divided into two groups: the experimental group included patients who had low intraabdominal resection of the rectum, whereas the control group consisted of patients who had abdominoanal resection of the rectum. We evaluated 5-year survival and patients' quality of life (using the Wexner and FIQL scales).Results. One year postoperatively, 17 patients (25 %) from the control group had unsatisfactory sphincter function (Wexner score 11–20). Sixty-three patients from the control group (95 %) reported fecal incontinence of varying severity. In the experimental group, 40 patients out of 88 (45 %) that survived during the first year had normal sphincter function. The remaining patients had solid stool incontinence or inability to retain feces for a long time (Wexner score <10).Conclusions. Low resections of the rectum ensured better functional outcomes and patients' quality of life than abdominoanal resections of the rectum did.
PENGEMBANGAN MEDIA PELATIHAN SIGNAL-SIGNAL WASIT BOLAVOLI MENGGUNAKAN M-LEARNING
Authors: Puspitasari Nutri , Nurrochmah Siti , Yudasmara Dona Sandy 
Published: November 2019

Abstrak:Tujuan penelitian dan pengembangan ini untuk mengembangkan media pelatihan signal-signal wasit bolavoli yang dikemas dalam bentuk buku digital mobile learning. Selain itu, media buku digital mobile learning diharapkan dapat mempermudah peserta kegiatan latihan untuk belajar dan mempraktekkan materi signal-signal wasit bolavoli secara mandiri. Model penelitian ini menggunakan model konseptual. Uji coba kelompok keseluruhan melibatkan 45 anggota kegiatan latihan. Produk yang dihasilkan dari penelitian ini adalah media pelatihan signal-signal wasit bolavoli menggunakan M-Learning. Dengan hasil analisis data uji coba kelompok kecil diperoleh persentase 89,33% dan hasil analisis data uji kelompok besar diperoleh persentase 92,81%. Kesimpulan pengembangan media pelatihan signal-signal wasit bolavoli menggunakan M-Learning dapat digunakan sebagai media yang tepat dan layak untuk anggota kegiatan Unit Aktivitas Bolavoli di Universitas Negeri Malang. Kata Kunci: Perwasitan bolavoli, Mobile Learning