bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nine Major Earthquakes in the United States of the Ionian Islands, 1815–1864
Authors: Albini Paola 
Published: September 2020

Abstract
Nine major earthquakes that affected the islands of Corfu, Paxoi, Lefkada, Kephalonia, Ithaca, and Zakynthos in the Ionian Sea offshore western Greece at the time of British Protectorate of the United States of the Ionian Islands (1815–1864) have been reappraised by means of a systematic investigation of contemporary, locally produced documents of diverse typologies. With an in-depth study of the earthquakes attested by multiple observations, this article complements and concludes the research focused on 50 yr of seismic records that was introduced by my recent companion article on the solitary records of earthquake effects throughout the Ionian Islands. Although some earthquakes discussed in this article had already been studied and interpreted in modern times, the exclusive use of carefully contextualized and independent records of earthquake effects allowed the author to overcome the imprecisions of preceding interpretations. Because of the exhaustive documentation, this study proposes a different vision of the characteristics of these nine major earthquakes from their dates of occurrence to newly assigned sets of intensity data.
The 1871 Lāna‘i Earthquake in the Hawaiian Islands
Authors: Butler Rhett 
Published: September 2020

Abstract
The historic Lāna‘i earthquake of 1871 is reappraised based on new science. This 1871 event occurred between O‘ahu and Maui, where currently 80% of the State of Hawai‘i population resides. I focus on expanding the considered modified Mercalli intensities (MMIs) applied in prior seismic hazard analyses and the application of an earthquake MMI–magnitude, duration–magnitude, and fault-scaling relations. Compared with the MMI–distance trend of the 2019 Mw 7.1 Ridgecrest, California, earthquake, the Lāna‘i event appears larger. The 1871 earthquake and other M≥4.9 earthquakes (measured instrumentally) trend along the Moloka‘i fracture zone (MFZ), suggesting a tectonic relationship. The MFZ near Hawai‘i is the boundary between ∼85 and ∼100  Ma age lithosphere. Consistent with the preponderance of available evidence and new science, I propose a hypothetical, revised Mw∼7.5 earthquake model of the 1871 Lāna‘i earthquake associated with the MFZ. This seismic event may credibly be considered as the third largest earthquake statewide in Hawai‘i’s history and the largest historic earthquake northwest of the Big Island of Hawai‘i.
Diferentes perspectivas da ação de membros inferiores nos quatro nados competitivos: uma revisão integrativa
Authors: Pinto Marcelo de Oliveira , Chirolli Milena Julia , Roesler Helio , Pereira Suzana Matheus 
Published: September 2020

Atualmente se sabe que a velocidade da natação é uma função da propulsão gerada a partir dos membros inferiores e não apenas dos membros superiores. No entanto, por anos, a ação das pernas, durante o nado, teve sua importância mitigada. Dessa forma, o objetivo deste trabalho foi levantar, por meio de uma revisão integrativa da literatura, o estado da arte acerca da importância dos membros inferiores na natação. Esta pesquisa foi delimitada na ação das pernas de superfície e pernas subaquáticas, excluindo-se as análises das saídas e viradas. Foram analisados estudos indexados nas seguintes bases de dados: Web of Science, PubMed, Scopus, Lilacs e SciELO. A sistematização de busca incluiu leitura de títulos, resumos e artigos na íntegra, encontrados por meio de blocos de descritores que combinaram termos principais e secundários. Um total de 154 artigos foi encontrado, dos quais 55 foram incluídos para análise qualitativa. Os resultados mostraram que os estudos sobre a utilização dos membros inferiores na natação possuem baixo valor amostral e descrição heterogênea dos níveis dos participantes. O nado peito e as ondulações subaquáticas são as variáveis mais estudadas. Preconiza-se examinar a eficácia de outras variáveis ​​antropométricas, cinemáticas e de coordenação para entender melhor a produção da velocidade máxima e considerar a importância de técnicas individuais na ação das pernas na natação. Ainda, no campo da utilização dos membros inferiores na natação, existem algumas lacunas, as quais os próprios artigos apontam. Essas demandas ficam por conta da força gerada por esses segmentos, além da discussão da importância em se considerarem fatores individuais na ação das pernas para os nadadores.
Relación familia-escuela y síndrome de Down: perspectivas de padres y profesores
Authors: Pereira-Silva Nara Liana , De Souza Rabelo Vanessa Célia , Fuentes Mejía Cristina 
Published: September 2020

Se investigó la relación entre familias con hijo con Síndrome de Down (SD) y la escuela (F-E) desde la perspectiva de familias y docentes de escuelas públicas en una ciudad del estado de Minas Gerais en Brasil. Fueron utilizados dos instrumentos para obtener información: entrevistas semiestructuradas y checklist para la caracterización de la rutina compartida y relación entre F-E. Para los progenitores la relación F-E se da en la estructura padresestudiante mientras que para las profesoras la relación F-E se produce mediante la estructura padres-profesores. Sin embargo, en los datos obtenidos en las entrevistas los progenitores señalan la relación F-E como fundamental para favorecer el desarrollo de habilidades de sus hijos con SD. Las profesoras consideran importante la relación F-E porque favorece el proceso de escolarización de niños con SD o Discapacidad Intelectual y añaden otros desafíos de constituir una escuela con enfoque inclusivo.
Relação entre inteligência e competências socioemocionais em crianças e adolescentes
Authors: De Cassia Nakano Tatiana , Della Torre de Moraes Isabella , De Oliveira Allan Waki 
Published: September 2020

A combinação entre as habilidades cognitivas e socioemocionais tem sido foco de interesse da literatura científica, dado o impacto de ambas sobre resultadoseducacionais, mercado de trabalho e comportamento social. Diante desse quadro, a presente pesquisa teve como objetivo, investigar a relação entre os construtos. Participaram do estudo 362 estudantes brasileiros do 3o ano (n=168) e 5o ano (n=194) do Ensino Fundamental, com idades entre 8 e 15 anos (M=10.3 anos; DP=1.33), sendo 180 do gênero feminino. Os participantes responderam a cinco subtestes de raciocínio para avaliação da inteligência (verbal, abstrato, numérico, espacial e lógico) e uma escala para avaliação das habilidades socioemocionais (composta pelos fatores de abertura a novas experiências, consciencia, extroversão, amabilidade, lócus de controle e estabilidade emocional). Os resultados mostraram correlações significativas entre os seis fatores que compõem as competências socioemocionais e a pontuação total na medida de inteligência, de modo a confirmar a importância de que ambas sejam estimuladas nos diferentes contextos.
Modelo de Personalidad Positiva: su asociación al funcionamiento óptimo en trabajadores activos
Authors: De la Iglesia Guadalupe , Lupano Perugini María Laura , Castro Solano Alejandro 
Published: September 2020

El objetivo de este trabajo fue identificar si el funcionamiento óptimo de trabajadores activos —entendido como una combinación de alto bienestar y performance— podía explicarse por la presencia de rasgos positivos de la personalidad. Se trabajó con una muestra de 400 trabajadores activos argentinos de entre 18 y 66 años (Medad=36.50, DE=11.81, 49.5% varones, 50.5% mujeres). Los resultados de regresiones lineales múltiples indicaron que los rasgos positivos incrementan la varianza explicada de las variables laborales estudiadas —performance, satisfacción y bienestar— al comparárselo con un modelo de predicción que solo incluía rasgos normales. Además, en un análisis discriminante, se concluyó que de todos los rasgos —positivos y normales— el que mejor discriminaba los grupos de alto/bajo funcionamiento óptimo era el rasgo positivo sprightliness.
Retardo Mental Sociocultural o Diferencias Cognitivas en niños de nivel socioeconómico bajo
Authors: Bravo Valdivieso Luis 
Published: September 2020

El autor analiza el término "relardo mental sociocultural" aplicado a minorías en EEUU que tienen un C.l. bajo o fronterizo y que presenlan problemas en el aprendizaje escolar, discute algunos estudios realizados en latinoamérica y presenta una comparación de los puntajes obtenidos por niños chilenos y norteamericanos en el WISC-R. Se concluye que el término «retardo mental socio cultural» es solamente un término explicativo inadecuado de las diferencias cognitivas y verbales entre sujeto de NSE medio y bajo.
Procesadores de Información : Una Tecnología blanda para el docente
Authors: Orantes Alfonso 
Published: September 2020

En este trabajo se presenta una aplicación de algunos recursos para procesar la información que se ha desarrollado dentro de la Psicología de la Instrucciónde fácil acceso al docente para facilitar su trabajo y el aprendizaje del estudiante. Estos recursos están dirigidos a estimular la participación activa delaprendiz. Representan una tecnología blanda, al alcance, medida y comprensión del docente con ventajas sobre las tecnologías convencionales apoyadas enaparatos que no se ajustan a nuestra ideosincrasia ni recursos. Se describe como contexto los factores que influyen en el aprendizaje de un texto (Aprendiz,Materiales, Actividades y la Dificultad de la Tarea).Asimismo se consideran factores como demandas de tarea, las estrategias de enseñanza y de aprendizaje y se describen sucintamente algunos trabajos venezolanos que han explorado variables moderadoras que afectan la eficiencia de este tipo de ayudas.
Variantes psicosociales y el uso e interpretación de pruebas psicológicas
Authors: Thorne Cecilia 
Published: September 2020

Se resalta la importancia de la adaptación, las normas y el análisis e interpretación cualitativa de los resultados. La autora ejemplifica cada uno de estos puntos a la luz de resultados de investigaciones llevadas a cabo en el medio con el WISC-R, Bender, Prueba de Discriminación Auditiva, las Láminas de Evaluación del Vocabulario y las Pruebas de Decodificación y Comprensión de Lectura Inicial. Se concluye que las pruebas pueden ser herramientas positivas de intervención y no simplemente ser utilizadas corno una constatación de diferencias entre grupos de distinto nivel sociocultural.
¿Porqué se refiere a los niños para evaluación y trabajo Psicoeducacional? Una revisión de la literatura sobre aspectos que influyen en la decisión de derivación
Authors: Pinzás García Juana , Tello Rosario 
Published: September 2020

El artículo resume literatura norteamericana sobre factores vinculados a cuan adecuada es la derivación de casos. Se presenta tres grupos de facopres: características de las profesoras, de los alumnos y de la tarea de derivación misma. Se describe cada grupo y se dan algunas recomendaciones generales con respecto a actividades previas a la decision de referir.
O processo de internacionalização e construção de um currículo cosmopolita
Authors: Backes José Licínio 
Published: September 2020

A presente entrevista com o professor José Augusto Pacheco, renomado pesquisador do campo do currículo e atualmente Presidente do Instituto de Educação da Universidade do Minho (Portugal), objetiva trazer algumas reflexões sobre o processo de internacionalização e cosmopolitismo do currículo, a centralidade do conhecimento para o campo do currículo e o impacto que as avaliações externas têm tido nos currículos de diferentes países que tendem a seguir cada vez mais as políticas globais e transnacionais.
Profil Pasien Kanker Paru Primer yang Dirawat Inap dan Rawat Jalan di Rumah Sakit Umum Daerah Dr Soetomo Surabaya
Authors: Chairudin Muhammad Rudy , Marhana Isnin Anang , Erawati Dyah 
Published: September 2020

Background: Lung cancer is still one of the biggest contributors to cancer deaths. GLOBOCAN in 2012 reported that lung cancer causes 30% of cancer deaths in men and 11.1% in women. Objective: The purpose of this study was to determine the profile of lung cancer in the General Academic Hospital Dr. Soetomo.Method: This research uses a descriptive observasional type by taking one time through medical record data from 186 primary lung cancer patients in Dr. Soetomo Hospital during January to December 2017. Results: Men (70.4%) more than women (29.6%). The most age group is 51-60 years (35.5%). Men and women suffer the most from adenocarcinoma (78.6% and 87.3%). Most jobs are private employees (38.2%). Most education is high school (70.4%). The most of patients live in East Java (97.3%) and the most specific are in Surabaya (39.2%). Most Histopathology is non-small cell lung cancer (95.9%) with adenocarcinoma is the most common type (81%). Lung cancer with small cell and non small cell type are mostly found in stage IV (82.3%) and extensive stage (3.8%). Local metastases are mostly found in the contralateral lung (58.1%), and most distant metastases in the brain organ (66.7%). The most common complication is pleural effusion (42.5%). Shortness of breath is the most common symptom (59.1%). The most widely used chemotherapy drug is pemetrexed-cisplatin (17.1%). Conclusion: Primary lung cancer patients at Dr. Soetomo Regional Academic Hospital majority of men aged 51-60 years. Most local metastases are in the contralateral lung and distant metastases in the brain. Most complications are pleural effusion.
Nepotes y limpieza de sangre en la Catedral de Toledo
Authors: Rodriguez de Gracia Hilario 
Published: September 2020

El presente artículo cuenta cómo se produjo la exclusión de tres criados del arzobispo Bernardo de Sandoval cuando obtuvieron unos beneficios eclesiásticos en la catedral de Toledo. Su pureza de sangre quedó en entredicho al confeccionar los expedientes de limpieza de sangre de Oviedo, Aldana y Rodríguez Benavente. El arzobispo Sandoval presionó a la corporación capitular para que fuesen admitidos y esa acción hizo que surgieran dos bandos. Unos canónigos se inclinaban por admitir a los nepotes del cardenal; el otro grupo tomó partido en defensa del Estatuto de limpieza. Defendían la imposibilidad de disfrutar de sus prebendas. Suman voluntades y ganan los defensores de la limpieza de sangre. Los tres candidatos apelan tal decisión en un largo litigio. Termina en la Rota donde surge una fuerte polémica, con presiones que influyen en la sentencia final. Pierden los tres criados del cardenal y el Estatuto del arzobispo Silíceo renace como piedra angular para ser canónigo o racionero.
ADHERANCE TO BREAST AND CERVICAL CANCER SCREENING ENSURING COMPLIANCE WITH ETHICAL PRINCIPLES IN THE REPUBLIC OF KAZAKHSTAN
Authors: Shamsutdinova A. G. , Turdaliyeva B. S. , Ramazanova B. A. , Beltenova A. G. 
Published: September 2020

The aim of the study was to assess adherence to breast and cervical cancer screening ensuring compliance with ethical principles.Material and methods. A total of 1,015 women of target age groups, living in Almaty, the Republic of Kazakhstan, participated in breast and cervical cancer screenings. A structured questionnaire was used to collect data from each participant (1,239 questionnaires: 674 for breast cancer screening and 565 for cervical cancer screening). Two hundred and twenty-four women participated in two screenings. The survey was conducted immediately after the respondents had had a mammography and / or Pap test. The questionnaire included the socio-demographic characteristics of women, questions on awareness of screening, level of knowledge before and after screening, sources of information, feelings before screening, after screening and and also after the receipt of test results. Binary logistic regression was used for data analysis.Results. Sixty-one percent (95 % CI 57.7; 63.1) of women participated in screening for the first time, 39 % (95 % CI 36.4; 41.8) of respondents visited outpatient clinic for the second and the third time. Multivariable analysis revealed that the participation in screening was associated with the purpose of visit, awareness and confidentiality. Thus, women, who arrived at the outpatient clinic with purposes other than screening were 2.3 times less (OR=2 95 % CI 1.6; 3.1) likely to participate in next screening compared to those, who came to the clinic with the purpose of screening as well as those, who were referred by employers (OR=2 95 % CI 1.2; 3.2) or friend/family (OR=2 95 % CI 1.0; 4.3). Women, who had little information about screening as a whole and about screening test before it was taken, were 3 and 2 times less likely to come to screening again (OR=3 95 % CI 1.6; 5.9 and OR=2 95 % CI 0.8; 3.7, respectively). The confidentiality violation led to a decrease in chance (OR=3.5 95 % CI 2.2; 4.9) of being screened again for those women, who experienced nervousness and shame during the screening, and also indicated the presence of nonmedical people during the test.Conclusion. Measures aimed to ensure compliance to ethics in screening for breast and cervical cancer will improve the quality of screening programs in accordance with international standards, as well as increase the personal responsibility for active participation in screening.
High-throughput profiling of antibiotic resistance genes in wastewater: comparison between a pond system in Namibia and an activated sludge treatment in Germany
Authors: Agrawal Shelesh , Orschler Laura , Sinn Jochen , Lackner Susanne 
Published: September 2020

Abstract
There are increasing concerns about wastewater treatment plants (WWTPs) acting as hotspots for antibiotic resistance genes (ARG). However, their role largely depends upon the treatment methods and antibiotics in the wastewater. To better understand these influences, we compared the occurrence and fate of ARG between a pond system in a developing country (Namibia) and an advanced WWTP (activated sludge system) in a developed country (Germany). A targeted metagenomic approach was used to investigate the wide-spectrum profiles of ARGs and their co-occurrence patterns at both locations. In total, 93 ARG subtypes were found in the German influent wastewater, 277 in the Namibian influent wastewater. The abundant ARG types found in Namibia and Germany differed, especially for multidrug resistance genes. The differences in occurrence and reduction can help to understand the performance of simple WWTP such as pond systems common in Namibia, where direct contact with wastewater is a potential risk for contamination.
Unraveling the Action Mechanism of Buyang Huanwu Tang (BYHWT) for Cerebral Ischemia by Systematic Pharmacological Methodology
Authors: Ma Shi-tang , Zhang Ning , Hong Ge , Feng Cheng-Tao , Hong Sheng-Wei , Dai Guo-Liang 
Published: September 2020

Background:
Buyang Huanwu Tang (BYHWT) and relevant Traditional Chinese
medicine (TCM) has its unique advantages in the treatment of cerebral ischemia. However, its pharmacological
mechanism has not been fully explained.

Objective:
Base on the multi-component, also the entire disease network targets, the present study
sets out to identify major bioactive ingredients, key disease targets, and pathways of BYHWT
against cerebral ischemia disease by systematic pharmacological methodology.

Methods:
Both the bioactive compounds from the BYHWT and the positive drugs against cerebral
ischemia were fully investigated. The binding targets of the positive drugs were then obtained. A
virtual screening protocol was then used to highlight the compound-target interaction and network
was constructed to visualize the compound-target binding effect after docking analysis. Moreover,
the targets enrichment analysis for biological processes and pathways were performed to further explore
the function of bio-targets protein gene and its role in the signal pathway.

Results:
A total of 382 active ingredients of the BYHWT and 23 candidate disease targets were
identified. Virtual screening results indicated that multiple bioactive compounds targeted multiple
proteins. Each compound acts on one or more targets. The mechanisms were linked to 20 signaling
pathways, and the key mechanism was related to serotonergic synapse, calcium signaling pathway
and camp signaling pathways.

Conclusion:
The present study explored the bioactive ingredients and mechanisms of BYHWT
against cerebral ischemia by systematic pharmacological methodology. The novel methodology
would provide a reference for the lead discovery of precursors, disease mechanism and material
base for TCM.
Antidepressant Drug Design on TCAs and Phenoxyphenylpropylamines
Utilizing QSAR and Pharmacophore Modeling
Authors: Kumar Amit , Nandi Sisir , Saxena Anil Kumar 
Published: September 2020

Background:
Depression is a mental illness caused by the imbalance of important neurotransmitters such as serotonin (5-HT) and norepinephrine (NE). It is a serious neurological disorder that could be treated by antidepressant drugs.

Objective:
There are two major classes such as TCAs and phenoxyphenylpropylamines which have been proven to be
broad-spectrum antidepressant compounds. Several attempts were made to design, synthesize and discover potent antidepressant compounds having the least toxicity and most selectivity towards serotonin and norepinephrine transporters. But
there is hardly any drug design based on quantitative structure-activity relationship (QSAR) and pharmacophore modeling
attempted yet.

Method:
In the present study, many TCAs (dibenzoazepine) and phenoxyphenylpropylamine derivatives are taken into consideration for pharmacophore feature generation followed by pharmacophoric distant related descriptors based QSAR modeling. Further, several five new congeners have been designed which are subjected to the prediction of biological activities
in terms of serotonin receptor affinity utilizing validated QSAR models developed by us.

Results:
An important pharmacophoric feature point C followed by the generation of a topography of the TCAs and phenoxyphenylpropylamine has been predicted. The developed pharmacophoric feature-based QSAR can explain 64.2% of the
variances of 5-HT receptor antagonism. The best training model has been statistically validated by the prediction of test set
compounds. This training model has been used for the prediction of some newly designed congeneric compounds which are
comparable with the existed drugs.

Conclusion:
The newly designed compounds may be proposed for further synthesis and biological screening as antidepressant agents.