bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alfabetização midiática e informacional na educação
Authors: Souza Ana Paula De 
Published: July 2020

RESUMOO artigo tem como objetivo despertar a discussão da importância da Alfabetização Midiática e Informacional na educação, tendo como base a educação brasileira como ponto de partida para estas análises. Atualmente, a sociedade vem sofrendo mudanças na sua estrutura devido a novas tecnologias digitais, principalmente na Educação, e, desta forma, traz novos desafios para o processo de ensino e aprendizagem. Faz-se necessário apresentar aos alunos as novas tecnologias e formá-los para delas usufruírem para os seus estudos, vida pessoal e trabalho. Este estudo foca nos benefícios para a área educacional quando esta conta com alunos portadores de habilidades para trabalharem com a informática e aparelhos tecnológicos diversos.
Progress in Alzheimer's Disease Research Based on SIRT1
Authors: Zhao Wenhui , Jin Qiu , Lin Bo , Zhu Xinshu 
Published: July 2020

<p>SIRT1 belongs to the family of Sirtuins deacetylase in mammals, which is mainly responsible for regulating the anti-infection, anti-apoptosis and anti-oxidative stress ability of cells. When organisms show degenerative changes in the nervous system, the expression level of SIRT1 will be up-regulated in order to play a protective role in the nervous system. In order to clarify the interaction between SIRT1 and Alzheimer's disease, this paper aims to provide scientific theoretical basis for the treatment of Alzheimer's disease by analyzing the regulation mechanism of SIRT1.</p>
Talking about the Problems of Hierarchical Teaching in Higher Vocational English and Its Solutions
Authors: Shen Yajie 
Published: July 2020

<p>With the continuous deepening of education reform, the education department has put forward higher requirements for higher vocational education. Higher vocational colleges and universities can not only cultivate professional technical talents, but also cultivate applicable talents in many aspects. At present, the students come from different places with different education background in the colleges and universities. In the process of English teaching, teachers should implement stratified teaching to further improve the quality of English teaching. This paper discusses the problems and countermeasures of stratified teaching in higher vocational English, analyzes the problems existing , and proposes effective solutions.</p>
DIMENSI METRIK KETETANGGAAN LOKAL GRAF HASIL OPERASI k-COMB
Authors: Pratama Fryda Arum , Susilowati Liliek , Utoyo Moh. Imam 
Published: July 2020

Research on the local adjacency metric dimension has not been found in all operations of the graph, one of them is comb product graph. The purpose of this research was to determine the local adjacency metric dimension of k-comb product graph and level comb product graph between any connected graph G and H. In this research graph G and graph H such as cycle graph, complete graph, path graph, and star graph. K-comb product graph between any graph G and H denoted by GokH. While level k comb product graph between any graph G and H denoted by GokH.In this research, local adjacency metric dimension of GokSm graph only dependent to multiplication of the cardinality of V(G) and many of k value, while GokKm graph and GokCm graph is dependent to dominating number of G and multiplication of the cardinality of V(G), many of k value, and local adjacency metric dimension of Km graph or Cm graph. And then, local adjacency metric dimension of GokSm graph only dependent to the cardinality of V(Gok-1Sm), while GokKm graph and GokCm graph is dependent to dominating number of G and multiplication of the local adjacency metric dimension of Km graph or Cm graph with cardinality of V(Gok-1Km) or V(Gok-1Cm).
Analisis Kestabilan dan Kontrol Optimal Model Matematika Dinamika Pelanggan Berdasarkan Kebijakan Pemasaran
Authors: Farchan Muhammad Iqbal Abdi , Fatmawati Fatmawati , Alfiniyah Cicik 
Published: July 2020

Customer dynamics include the exchange of information and ongoing transactions between customers and the organization. This process has an important role in the company to run its business, so that the number of customers increase. To achieve this, many things are done by the company. One of the strategies is product advertising by word of mouth. The purpose of this thesis is to analyze the stability of equilibrium point and to apply the optimal control word of mouth advertising on mathematics model of the customer dynamics based on marketing policy. Mathematics model of the customer dynamics based on marketing policy without control has two equilibrium points, namely non – endemic equilibrium (E0) and endemic equilibrium (E1). Local stability of equilibrium and the existence of endemic equilibrium depends on basic reproduction number (R0). The non – endemic equilibrium tend to asymptotically stable if R0 < 1. The problem of optimal control is solved by Pontryagin’s Maximum Principle. The simulation results show that the total number of referral and regular customer populations that are given control in the form of word of mouth advertising efforts at the end of the observation are 312 and 18470 with the control effort costs occurred in 1798364.63. While the total number of referral and regular customer populations that are not given control in the form of word of mouth advertising efforts at the end observation are 241 and 17260. Based on these results show that word of mouth advertising efforts have an effect to increase the number of referral and regular customer in accordance with the aim of providing optimal control.
Samba novo e samba de morro: política e sonoridade em Opinião de Nara
Authors: Gerolamo Ismael De Oliveira 
Published: July 2020

Partindo de apreciações e escutas da produção de Nara Leão durante a década de 1960 e mais detidamente de seu segundo disco, o presente trabalho busca lançar luz à efetivação de uma “primeira guinada” em sua trajetória, na pretensão de contribuir para delinear um esboço da personalidade musical da cantora. De formação bossa-novista, a intérprete tornou-se uma das figuras de referência da vertente engajada da canção brasileira em meados da referida década. Sua produção evidencia um duplo movimento efetuado por alguns cancionistas no período: um retorno a certas tradições da canção popular entendida enquanto fonte primordial a informar um projeto poético (e político) e a manutenção de procedimentos musicais entendidos como novos ou modernos (embora uma espécie de ruptura com a bossa nova, então sinônimo de modernidade, tenha sido até certo ponto efetuado).
Economic Law Creation Beautiful Global Indonesia
Authors: Susanti Liana Endah 
Published: July 2020

<p><em>Indonesia is the world 's largest archipelago with 1,904,569 km2 of surface area. A very diverse landscape with a variety of abundance of flora and fauna is a special attraction for foreign tourists. Not only that, the natural wealth in Indonesia 's intestines is also very abundant, as are various minerals and richness from other mining materials. However, a abundance of skilled human capital, both in terms of science and technology mastered, do not complement the plentiful natural resources. This is one of the reasons superpowers should be providing cooperation. PT. PT. Freeport is an clear example of Indonesia 's collaboration in the mining sector with foreign parties. The first contract for Freeport-Indonesia was established in 1967. After the Foreign Investment Law was passed in 1967, Freeport became the first foreign mining firm to operate in Indonesia. But the existence of this partnership was regretted by many because it was perceived to be detrimental to the region. The reason is that so far nobody knows for sure how much gold and silver has been produced from the mining to date. The magnitude of the distribution of mining goods is also not quite good given that Indonesia owns land which is turned into gold fields. There are, in fact, many reports uncovering miserable stories of discrimination by indigenous people around the mining region. Justice is once again present as something that is not only wishful thinking, but also noble values that have to be realized for the collective good of the state goals set out in the Pancasila points and the preamble to the Constitution of 1945.</em></p><p><em> </em></p><p><strong>Keywords</strong>: <em>Mining, PT. Freeport, Discrimination, justice</em><em></em></p>
Iatrogenic Distal Radial Physeal Fracture During Insertion of Intramedullary Fixation for a Both Bone Forearm Fracture
Authors: Bryan Cory A. , Hyer Lauren C. , Westberry David E. 
Published: July 2020

Case:
A 12-year-old boy with an isolated both bone forearm fracture was treated with closed reduction and flexible intramedullary nailing 11 days postinjury and after the loss of initial fracture alignment. On nail insertion, an intraoperative distal radial physeal fracture was encountered, thereby warranting modification in treatment.

Conclusion:
Physeal injury is a rare intraoperative complication of intramedullary fixation of forearm fractures. This report provides insight regarding the management and prevention of this rare complication.
Upper Mantle Anisotropy beneath the Western Segment, NW Indian Himalaya, Using Shear Wave Splitting
Authors: Biswal Shubhasmita , Kumar Sushil , Roy Sunil K. , Kumar M. Ravi , Mohanty W. K. , Parija Mahesh Prasad , Paul Ajay 
Published: July 2020

Abstract
This study investigates the upper mantle deformation pattern beneath the Indo-Eurasia collision zone utilizing the core-refracted (S(K)KS) phases from 167 earthquakes recorded by 20 broadband seismic stations deployed in the Western Himalaya. The 76 new shear wave splitting measurements reveal that the fast polarization azimuths (FPAs) are mainly oriented in the ENE-WSW direction, with the delay times varying between 0.2 and 1.7 s. The FPAs at most of the stations tend to be orthogonal to the major geological boundaries in the Western Himalaya. The average trend of the FPAs at each station indicates that the seismic anisotropy is primarily caused due to strain-induced deformation in the top ~200 km of the upper mantle as a result of the ongoing Indo-Eurasian collision. A contribution from the mantle flow in the direction of the Indian plate motion is possible. The mantle strain revealed in the present study may be due to a combination of basal shear resulting from plate motion and ductile flow along the collision front due to compression.
Autism Spectrum Disorders in Mali: Parental concerns about child developmental milestones and late diagnostic age
Authors: Sangare Modibo , Diarra Ya , Konate Djeneba , Haidara Mohamed S , Karembe Adama , Keita Boureima , Dolo Housseini , Kouyate Modibo , Doumbia Fatoumata , Sidibe Oumar , Diakite Seidina , Kayentao Kassoum , Traore Drissa , Toure Amadou , Doumbia Seydou , Diakite Mahamadou , Kim Hyung-Goo , Awandare Gordon A 
Published: July 2020

Abstract
Background: In Mali, the national health facility-based prevalence of autism spectrum disorders (ASD) was 4.5% (105/2,343) and the age of first medical visit for autistic children was around 7 years old in 2018. Parental recognition of developmental abnormalities initiates the early autism detection and diagnosis. Our aim was to investigate if parental concerns were associated with early first medical visits and subsequent ASD diagnostic in Mali. Methods: We conducted a pilot study from November 2017 to July 2019. We surveyed parents of 57 out of 60 available autistic children aged 3-14 years old. Results: Parents were concerned over verbal communication in 54.1% and reciprocal social interaction in 43.8%. Children with ASD had their first medical visit after 18 months old in 66.7%, ≥ two medical visits in 87.7%, and were identified after 36 months old in 76.8%. Conclusion: Parental concerns were not significantly associated with early first medical visit and ASD identification. Our results will guide future full scale studies on parental concerns in ASD in Mali.
Does the Fixation Span Impact on Results of Surgical Correction of Pediatric Congenital Spine Deformities? Analysis of a Monocentric Cohort
Authors: Ryabykh Sergey O , Filatov Egor Yu , Mejabi Joseph Olorunsogo , Savin Dmitry M , Gubin Alexander B 
Published: July 2020

Abstract
Background: We aimed at reviewing results of surgical correction of congenital spinal deformity with regard to length of instrumentation and type of osteotomy.Methods. Study comprised 117 patients with congenital spinal deformity treated between 2010 and 2018. Patients’ aged 1 to 18 years. Mean follow-up was 3 years (1 to 8). Posterior approach was used in all cases. Patients were subdivided into 4 groups.Result: Monosegmental unilateral fixation (Group I) for 15 children with mean age of 48.3 months. Cobb angle for scoliosis and kyphosis were 31.1° and 29.3° corrected to 74.9% and 84.0% respectively. Blood loss was 213.6 mL. Operating time was 165 minutes.Monosegmental bilateral fixation (Group II) for 24 patients with mean age of 53.1 months. Cobb angle for scoliosis and kyphosis were 32.5° and 30.9° corrected to 83.7% and 100.6% respectively. Blood loss was 215.4 mL. Operating time was 160.5 minutes.Three segmental bilateral fixation (Group III) for 29 patients with mean age of 78.2 months. Cobb angle for scoliosis and kyphosis were 36.6° and 37.6° corrected to 83.1% and 86.7% respectively. Blood loss was 342.7 mL. Operating time was 197.0 minutes. Polysegmental bilateral fixation (Group IV) for 49 children with mean age of 112.7 months. Cobb angle for scoliosis and kyphosis were 40° and 58.2° corrected to 72.5% and 81.6% respectively. Blood loss was 549.3 mL. Operating time was 288.8 minutes.Conclusion: Choice of spinal fixation technique was determined on the basis of patient’s age, magnitude of the deformity and concomitant vertebral abnormalities.
Automated Needle Targeting (ANT) Device-Assisted Renal Access during Percutaneous Nephrolithotripsy (PCNL) Puncture: A Pilot Study to Assess the Safety and Efficacy of a Novel Technique
Authors: Chai Chu Ann , Yeoh W.S , Fadzli A.N , Ong T.A , Kuppusamy S , Aung K.P , Lim J. , Razack A.H Azad 
Published: July 2020

Abstract
Background: To explore the use of an automated needle targeting (ANT) device as an assistive intraoperative navigation modality during PCNL for the treatment of large renal stones, with the aim of reducing surgical durations and radiation exposure.Methods: This open-label, single-surgeon clinical trial included patients with a diagnosis of renal stones for whom PCNL using the ANT device via the percutaneous access technique was indicated. Ethical approval was obtained from the UMMC ethics review board (Ref. 20118105-6740). The ANT was assembled after an initial motor calibration, and the image calibration was performed using the patient’s fluoroscopic images. Subsequently, the ANT software calculated a bullseye alignment before percutaneous puncture. Accurate renal access was confirmed by the efflux of urine in the Chiba biopsy needle, as well as by imaging with the C-arm intensifier at different angles. The primary endpoints were the time to successful renal access (from ANT set-up to urine efflux) and adverse events.Results: In all cases, successful renal access was achieved with a single attempt. The mean time to renal access was 6 minutes, 8 seconds. The mean fluoroscopy duration was 101 seconds, with a mean radiation dose of 23.46 mGy. No adverse events were documented.Conclusion: The ANT device enabled successful, safe and efficient renal access for PCNL in this study. Further research is needed to justify the effectiveness of this device in terms of enabling accurate renal access while reducing the surgical duration and radiation exposure to both surgeons and patients.
Reference Genes for Quantitative qPCR Analyses in Monocytes of Septic Patients
Authors: Gritte Raquel Bragante , Souza-Siqueira Talita , Masi Laureane Nunes , Germano Juliana de Freitas , Murata Gilson Masahiro , Machado Marcel Cerqueira Cesar , Pithon-Curi Tania Cristina , Curi Rui , Soriano Francisco Garcia 
Published: July 2020

Abstract
Background: Monocytes and macrophages are essential components of the innate and adaptive immune responses and play a critical role in sepsis. Sepsis is a life-threatening organ dysfunction associated with an unregulated host response to infection. About 20 million people develop sepsis annually, and up to 50% die. There is a lack of studies regarding human monocytes and sepsis. This study aimed to determine the most stable internal gene (s) to investigate gene expression in monocytes/macrophages of septic patients.Methods: The expression stability of fifteen commonly used reference genes was analyzed by determining the comparative threshold cycle (Ct) values, using the BestKeeper, GeNorm, and NormFinder algorithms.Results: BestKeeper analysis revealed that the syntaxin 5 (STX5A) and hypoxanthine phosphoribosyltransferase 1 (HPRT1) genes were highly stable. GeNorm pointed out STX5A and phosphoglycerate kinase 1 (PGK1) as the most suitable combination whereas through NormFinder glyceraldehyde 3- phosphate dehydrogenase (GAPDH) and 14-3-3 zeta/delta protein (YWHAZ) was the most stable combination. All programs analysis discarded the use of heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB). GeNorm and NormFinder indicated actin-beta (ACTB) as the least stable gene.Conclusions: The combined data indicated that STX5A, PGK1, GAPDH, and HPRT1 are highly suitable reference genes for qPCR analysis of septic patients monocytes. In the case of choosing one single reference gene, the results point out to STX5A (first place by GeNorm and BestKeeper and third place by NormFinder). This study is the first report on reference genes in monocytes/macrophages from septic patients.
Enlarged Craniotomy with Membranectomy for Treatment of Completely Organized Chronic Subdural Hematoma: A Case Report and Literature Review
Authors: Shi Xiao-Yong , Zhang Jin-Xia , Tang Zhu-Xiao , Sun Hu , Shen Zheng 
Published: July 2020

Abstract
Background Chronic subdural hematoma(CSDH) is a common condition in the elderly which can be treated by burr hole trephination and drainage. But completely organized chronic subdural hematoma(OCSH) is rare which cannot be cured by this technique, only treated by enlarged craniotomy and membranectomy.Case Presentation A 74-year old man admitted to hospital for loss of consciousness for one hour following a car accident. Cranial computed tomography (CT) showed a large mixed density hematoma on the left, acute subdural hematoma, cerebral contusion and subarachnoid hemorrhage. A left standard large craniotomy was performed. A large and completely OCSH with no liquid component was found during surgery, at the same time, we found no obvious adhesions between the inner membrane and the brain tissue, which was easy to separate and finally removed completely. Conclusion Craniotomy with membranectomy is a feasible method for treating completely OCSH.
How COVID-19 pandemic has changed haematological care
Authors: Fouquet G. , Franchi Patricia , Mittaine-Marzac Benedicte , Laporte N. , Ihaddadene Hanya , Decroocq Justine , Breal Claire , Bouscary Didier , Ammar Fatiha , Zogo Arsene , Burgun Sylvie , Zerbit Jeremie , Willems Lise , Deau-Fischer Benedicte , Vignon Marguerite 
Published: July 2020

Abstract
Background : Datas from China suggest that patients with cancer have more severe outcome in case of covid-19 infection. Patients with haematological disease have often immunosuppression, due to the underlying disease and to their treatment. Methods: We recorded the consecutive patients usually treated in our haematology department diagnosed with COVID-19 infection between March 10th to April 30th. To evaluate the impact of the pandemic, we compare the activity of our department during two twenty working-days periods: March 20th to April 17th (“Covid month”) and February 18th to March 16th 2020 (“Covid-free month”). Results: Fifty patients treated in our haematology department had a COVID-19 infection, diagnosed with PCR or CT-scanner. Half of them were still on chemotherapy treatment, 30% were on survey after treatment and 20% were on a “watch and wait” strategy. Sixteen patients ( 30%) evolved to an acute respiratory syndrome with a fatal outcome in ten cases. (20%). The severity of the disease prompted us to change the organization of our department to protect our patients. We followed international recommendation and delayed non urgent procedure. this allowed a reduction of 10% of our activity. Moreover, we managed to treat 25% of our patients coming usually in outpatient clinic with tele-health. Thanks to hospital-at-home, these patients could receive their treatment and stay safe at home. Conclusion: This retrospective study give an insight of how covid-19 outbreak will change cancer care.
Perceptions Regarding Hepatitis B and C diseases, and their Risk Factors among Ward Boys Working in Tertiary Care Hospitals of Islamabad
Authors: Ranani Salman Muhammad Soomar , Abdullah Muhammad , Ahmed Ejaz , Javed Amar 
Published: July 2020

Abstract
Background: Hepatitis is a serious global public health issue. There are about 36 million healthcare professionals globally, out of which approximately 3 million per year get an injury from some sharps, thus resulting in 2 million subjects being infected with HBV and 1 million with HCV (WHO). Methods: A qualitative study, with Phenomenological approach, was conducted among ward boys of Islamabad. A total of 25 in-depth interviews were conducted by the principal researcher from ward boys, 12 and 13 from the public and private sector hospital till the saturation was achieved.Results: It was found that ward boys lacked comprehensive knowledge about the disease process. They did not adopt precautionary measures and they lack training and knowledge about the spread of infection which was close to none. Ward boys that are subjects of this study were not compelled and penalize to follow infection control standards which led to the downfall of the system and provided a way for infection to proliferate and prosper.Conclusion: From this study, it is concluded that ward boys in private and public tertiary care hospitals are at high risk of acquiring Hepatitis B and C infection. They lacked knowledge about the infective disease and its preventions. Certifications should be made mandatory for ward boys to allow for work in this environment.