bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impulsive decision-making predicts the course of substance-related and addictive disorders
Authors: Kräplin Anja , Höfler Michael , Pooseh Shakoor , Wolff Max , Krönke Klaus-Martin , Goschke Thomas , Bühringer Gerhard , Smolka Michael N. 
Published: June 2020

Abstract
Background
This study investigated whether patterns of impulsive decision-making (i) differ between individuals with DSM-5 substance use disorders (SUD) or non-substance-related addictive disorders (ND) and healthy controls, and (ii) predict the increase of SUD and ND severity after one year.

Methods
In a prospective-longitudinal community study, 338 individuals (19–27 years, 59% female) were included in one of three groups: SUD (n = 100), ND (n = 118), or healthy controls (n = 120). Group differences in four impulsive decision-making facets were analyzed with the Bayesian priors: delay discounting (mean = 0.37, variance = 0.02), probability discounting for gains and for losses (each − 0.16, 0.02), and loss aversion (− 0.44, 0.02). SUD and ND severity were assessed at baseline and after 1 year (n = 312, 92%). Predictive associations between decision-making and SUD/ND severity changes were analyzed with the Bayesian prior: mean = 0.25, variance = 0.016.

Results
Compared with controls, the SUD group displayed steeper delay discounting and lower probability discounting for losses; the ND group displayed lower probability discounting for losses (posterior probabilities > 98%). SUD symptom increase after 1 year was predicted by steeper delay discounting and lower loss aversion; ND symptom increase by lower probability discounting for losses and lower loss aversion (posterior probabilities > 98%). There was low evidence for predictive relations between decision-making and the quantity-frequency of addictive behaviours.

Discussion
Impulsive decision-making characterizes SUD and ND and predicts the course of SUD and ND symptoms but not the engagement in addictive behaviours. Strength of evidence differed between different facets of impulsive decision-making and was mostly weaker than a priori expected.
Mycotoxin Biodegradation Ability of the Cupriavidus Genus
Authors: AL-Nussairawi Mohammed , Risa Anita , Garai Edina , Varga Emese , Szabó István , Csenki-Bakos Zsolt , Kriszt Balázs , Cserháti Mátyás 
Published: June 2020

AbstractThe biodegradation and biodetoxification ability of five prominent mycotoxins, namely aflatoxin B1 (AFB1), ochratoxin-A (OTA), zearalenone (ZON), T-2 toxin (T-2) and deoxynivalenol (DON) of Cupriavidus genus were investigated. Biological methods are the most appropriate approach to detoxify mycotoxins. The Cupriavidus genus has resistance to heavy metals and can be found in several niches such as root nodules and aquatic environments. The genus has 17 type strains, 16 of which have been investigated in the present study. According to the results, seven type strains can degrade OTA, four strains can degrade AFB1, four strains can degrade ZON and three strains can degrade T-2. None of the strains can degrade DON. The biodetoxification was measured using different biotests. SOS-chromotest was used for detecting the genotoxicity of AFB1, the BLYES test was used to evaluate the oestrogenicity of ZON, and the zebrafish embryo microinjection test was conducted to observe the teratogenicity of OTA, T-2 and their by-products. Two type strains, namely C. laharis CCUG 53908T and C. oxalaticus JCM 11285T reduced the genotoxicity of AFB1, whilst C. basilensis DSM 11853T decreased the oestrogenic of ZON. There were strains which were able to biodegrade more than two mycotoxins. Two strains degraded two mycotoxins, namely C. metalliduriens CCUG 13724T (AFB1, T-2) and C. oxalaticus (AFB1, ZON) whilst two strains C. pinatubonensis DSM 19553T and C. basilensis degraded three toxins (ZON, OTA, T-2) and C. numazuensis DSM 15562T degraded four mycotoxins (AFB1, ZON, OTA, T-2), which is unique a phenomenon amongst bacteria.
Demonstration of variable angle super-heterodyne dynamic light scattering for measuring colloidal dynamics
Authors: Crowley Daniel , Dekker Riande I. , Botin Denis , Schartl Nicole , Groß Annalena , Agarwal Aakanksha , Heidt Sabrina , Wenzl Jennifer , Zaghi Negar , Vorobev Evgenii , Palberg Thomas 
Published: June 2020

AbstractWe demonstrate a prototype light scattering instrument combining a frequency domain approach to the intermediate scattering function from Super-Heterodyning Doppler Velocimetry with the versatility of a standard homodyne dynamic light scattering goniometer setup for investigations over a large range of scattering vectors. Comparing to reference experiments in correlation-time space, we show that the novel approach can determine diffusion constants and hence hydrodynamic radii with high precision and accuracy. Possible future applications are discussed shortly.
Analytical approximations for the inverse Langevin function via linearization, error approximation, and iteration
Authors: Howard Roy M. 
Published: June 2020

AbstractThis paper details an analytical framework, based on an intermediate function, which facilitates analytical approximations for the inverse Langevin function—a function without an explicit analytical form. The approximations have relative error bounds that are typically much lower than those reported in the literature and which can be made arbitrarily small. Results include convergent series expansions in terms of polynomials and sinusoids which have modest relative error bounds and convergence properties but are convergent over the domain of the inverse Langevin function. An important advance is to use error approximations, and then iterative relationships, which allow simple initial approximations for the inverse Langevin function, with modest relative errors, to generate approximations with arbitrarily low relative errors. One example is that of an initial approximating function, with a relative error bound of 0.00969, which yields relative error bounds of 2.77 × 10−6 and 2.66 × 10−16 after the use of first-order error approximation and then first-order iteration. Functions with much lower error bounds are possible and are detailed. First- and second-order Taylor series can be used to simplify the error- and iteration-based approximations.
Randomised-controlled feasibility trial on abdominal wall closure techniques in patients undergoing relaparotomy (ReLap study; DRKS00013001)
Authors: Probst Pascal , Tran Dinh Thien-An , Hüttner Felix J. , Harnoss Julian C. , Heger Patrick , Ritter Alina S. , Doerr-Harim Colette , Mihaljevic André L. , Knebel Phillip , Schneider Martin , Büchler Markus W. , Diener Markus K. 
Published: June 2020

Abstract
Background
Patients undergoing relaparotomy are generally underrepresented in clinical trials, despite how common the procedure is in clinical practice. Specifically, techniques for re-do abdominal wall closure have never been evaluated in a randomised-controlled trial. The aim of this trial was to identify the optimal abdominal wall closure technique in patients undergoing relaparotomy.

Methods
In this monocentric, randomised feasibility trial, patients scheduled for elective relaparotomy were randomised to abdominal wall closure with either the small stitches technique, using Monomax® 2-0, or the large stitches technique, using PDS II® 1 loop. Patients’ postoperative courses were followed for 1 year after the index operation. Effectiveness and safety outcomes were compared at a level of significance of 5% between the two techniques.

Results
A total of 100 out of 131 patients (76.3%) were evenly randomised to the small stitches and large stitches groups. The time for abdominal wall closure did not differ between the two techniques (small stitches 27.5 ± 9.5 min versus large stitches 25.3 ± 12.4 min; p = 0.334). The overall comprehensive complication index was 14.4 ± 15.5 in the small stitches group and 19.9 ± 23.4 in the large stitches group (p = 0.168). Specifically, rates of surgical site infection (small stitches 30.0% versus large stitches 36.0%; p = 0.524) and burst abdomen (small stitches 4.0% versus large stitches 0.0%; p = 0.495) did not differ. After 1 year, incisional hernia rate was 7.5% in the small stitches group and 10.0% in the large stitches group (p > 0.999).

Discussion
Both abdominal wall closure techniques investigated in this trial were feasible in relaparotomy patients. This exploratory trial revealed no noticeable difference in the effectiveness or safety of the small stitches technique with Monomax® 2-0 versus the large stitches technique with PDS II® 1 loop. Therefore, surgeons should stay with their preferred suture technique in relaparotomy patients.

Trial registration
Deutsches Register Klinischer Studien (www.germanctr.de): DRKS00013001
Canadian taTME expert collaboration (CaTaCO) position statement
Authors: Caycedo-Marulanda Antonio , Brown Carl J. , Chadi Sami A. , Ashamalla Shady , Lee Lawrence , Stotland Peter , Hameed Usmaan , Melich George , Ma Grace , Letarte Francois , Karimuddin Ahmer , Quereshy Fayez , Phang Terry , Raval Manoj , Vikis Elena , Liberman A. Sender , Bouchard Alexandre , Bouchard Phillipe , Drolet Sebastien 
Published: June 2020

Abstract
Introduction
Transanal total mesorectal excision (taTME) is a novel approach to surgery for rectal cancer. The technique has gained significant popularity in the surgical community due to the promising ability to overcome technical difficulties related to the access of the distal pelvis. Recently, Norwegian surgeons issued a local moratorium related to potential issues with the safety of the procedure. Early adopters of taTME in Canada have recognized the need to create guidelines for its adoption and supervision. The objective of the statement is to provide expert opinion based on the best available evidence and authors’ experience.

Methods
The procedure has been performed in Canada since 2014 at different institutions. In 2016, the first Canadian taTME congress was held in the city of Toronto, organized by two of the authors. In early 2019, a multicentric collaborative was established [The Canadian taTME expert Collaboration] which aimed at ensuring safe performance and adoption of taTME in Canada. Recently surgeons from 8 major Canadian rectal cancer centers met in the city of Toronto on December 7 of 2019, to discuss and develop a position statement. There in person, meeting was followed by 4 rounds of Delphi methodology.

Results
The generated document focused on the need to ensure a unified approach among rectal cancer surgeons across the country considering its technical complexity and potential morbidity. The position statement addressed four domains: surgical setting, surgeons’ requirements, patient selection, and quality assurance.

Conclusions
Authors agree transanal total mesorectal excision is technically demanding and has a significant risk for morbidity. As of now, there is uncertainty for some of the outcomes. We consider it is possible to safely adopt this operation and obtain adequate results, however for this purpose it is necessary to meet specific requirements in different domains.
Unpacking the Role of Boundaries in Computer-Supported Collaborative Teaching
Authors: Willermark Sara , Pareto Lena 
Published: June 2020

AbstractIn this study, we explore the role of boundaries for collaborative learning and transformation of work practices to occur. We report from a three-year action research project including well over 1800 h of participation by the authors. The empirical data are based on project participation work including observations and field notes, project reports, interviews and a questionnaire, within a school development project in Nordic elementary school. In the project, teachers and researchers from three Nordic countries, Norway, Sweden and Denmark, collaborated to develop novel, on-line teaching models for a Nordic Virtual Classroom. The virtual classroom refers to an educational setting where teaching and learning activities are conducted collaboratively in cross-national teams “in the cloud” by means of information technology. During the project, teachers were challenged in their current teaching practices and the project resulted in collaborative learning and transformation of work practice. In this paper, we explore underlying reasons for such transformation to occur by unpacking how and why boundaries can play a role in computer-supported collaborative teaching and stimulate a transformation towards digitalized teaching practices. The paper contributes with an explanation of how the composition of boundaries of a technological, organizational, and cultural nature operates and constitutes a resource for learning and principles for how boundaries can be used for such purpose.
Homogenization of Perforated Elastic Structures
Authors: Griso Georges , Khilkova Larysa , Orlik Julia , Sivak Olena 
Published: June 2020

AbstractThe paper is dedicated to the asymptotic behavior of $\varepsilon$
ε
-periodically perforated elastic (3-dimensional, plate-like or beam-like) structures as $\varepsilon \to 0$
ε
→
0
. In case of plate-like or beam-like structures the asymptotic reduction of dimension from $3D$
3
D
to $2D$
2
D
or $1D$
1
D
respectively takes place. An example of the structure under consideration can be obtained by a periodic repetition of an elementary “flattened” ball or cylinder for plate-like or beam-like structures in such a way that the contact surface between two neighboring balls/cylinders has a non-zero measure. Since the domain occupied by the structure might have a non-Lipschitz boundary, the classical homogenization approach based on the extension cannot be used. Therefore, for obtaining Korn’s inequalities, which are used for the derivation of a priori estimates, we use the approach based on interpolation. In case of plate-like and beam-like structures the proof of Korn’s inequalities is based on the displacement decomposition for a plate or a beam, respectively. In order to pass to the limit as $\varepsilon \to 0$
ε
→
0
we use the periodic unfolding method.
Global assessment of environment, health and economic impact of the novel coronavirus (COVID-19)
Authors: Sarkodie Samuel Asumadu , Owusu Phebe Asantewaa 
Published: June 2020

AbstractThe institution of social distancing and punitive measures to contain the spread of COVID-19 through human-to-human transmission has environmental, health and economic impact. While the global pandemic has led to the enhancement of the health system and decline of emissions, economic development appears deteriorating. Here, we present the global environmental, health and economic dimension of the effect of COVID-19 using qualitative and empirical assessments. We report the health system policies, environmental sustainability issues, and fiscal, monetary and exchange rate measures introduced during lockdown across countries. While air pollution is reported to have declined, municipal and medical waste is increasing. The COVID-19 global pandemic uncertainty ranks the UK as the country with the highest uncertainty level among 143 countries. The USA has introduced 100% of pre-COVID-19 crisis level GDP, the highest policy cut-rate among 162 countries. Science, innovation, research and development underpin COVID-19 containment measures implemented across countries. Our study demonstrates the need for future research to focus on environment-health-economic nexus—a trilemma that has a potential trade-off.
Local error estimation and step size control in adaptive linear multistep methods
Authors: Arévalo Carmen , Söderlind Gustaf , Hadjimichael Yiannis , Fekete Imre 
Published: June 2020

AbstractIn a k-step adaptive linear multistep methods the coefficients depend on the k − 1 most recent step size ratios. In a similar way, both the actual and the estimated local error will depend on these step ratios. The classical error model has been the asymptotic model, chp+ 1y(p+ 1)(t), based on the constant step size analysis, where all past step sizes simultaneously go to zero. This does not reflect actual computations with multistep methods, where the step size control selects the next step, based on error information from previously accepted steps and the recent step size history. In variable step size implementations the error model must therefore be dynamic and include past step ratios, even in the asymptotic regime. In this paper we derive dynamic asymptotic models of the local error and its estimator, and show how to use dynamically compensated step size controllers that keep the asymptotic local error near a prescribed tolerance tol. The new error models enable the use of controllers with enhanced stability, producing more regular step size sequences. Numerical examples illustrate the impact of dynamically compensated control, and that the proper choice of error estimator affects efficiency.
Logical ignorance and logical learning
Authors: Pettigrew Richard 
Published: June 2020

AbstractAccording to certain normative theories in epistemology, rationality requires us to be logically omniscient. Yet this prescription clashes with our ordinary judgments of rationality. How should we resolve this tension? In this paper, I focus particularly on the logical omniscience requirement in Bayesian epistemology. Building on a key insight by Hacking (Philos Sci 34(4):311–325, 1967), I develop a version of Bayesianism that permits logical ignorance. This includes: (i) an account of the synchronic norms that govern a logically ignorant individual at any given time; (ii) an account of how we reduce our logical ignorance by learning logical facts and how we should update our credences in response to such evidence; and (iii) an account of when logical ignorance is irrational and when it isn’t. At the end, I explain why the requirement of logical omniscience remains true of ideal agents with no computational, processing, or storage limitations.
Algebraic, Rational and Puiseux Series Solutions of Systems of Autonomous Algebraic ODEs of Dimension One
Authors: Cano José , Falkensteiner Sebastian , Sendra J. Rafael 
Published: June 2020

AbstractIn this paper, we study the algebraic, rational and formal Puiseux series solutions of certain type of systems of autonomous ordinary differential equations. More precisely, we deal with systems which associated algebraic set is of dimension one. We establish a relationship between the solutions of the system and the solutions of an associated first order autonomous ordinary differential equation, that we call the reduced differential equation. Using results on such equations, we prove the convergence of the formal Puiseux series solutions of the system, expanded around a finite point or at infinity, and we present an algorithm to describe them. In addition, we bound the degree of the possible algebraic and rational solutions, and we provide an algorithm to decide their existence and to compute such solutions if they exist. Moreover, if the reduced differential equation is non trivial, for every given point $$(x_0,y_0) \in \mathbb {C}^2$$

(

x
0

,

y
0

)

∈

C

2

, we prove the existence of a convergent Puiseux series solution y(x) of the original system such that $$y(x_0)=y_0$$

y

(

x
0

)

=

y
0

.
Translational Intracerebral Hemorrhage Research: Has Current Neuroprotection Research ARRIVEd at a Standard for Experimental Design and Reporting?
Authors: Liddle Lane J. , Ralhan Shivani , Ward Daniel L. , Colbourne Frederick 
Published: June 2020

AbstractOne major aim of preclinical intracerebral hemorrhage (ICH) research is to develop and test potential neuroprotectants. Published guidelines for experimental design and reporting stress the importance of clearly and completely reporting results and methodological details to ensure reproducibility and maximize information availability. The current review has two objectives: first, to characterize current ICH neuroprotection research and, second, to analyze aspects of translational design in preclinical ICH studies. Translational design is the adoption and reporting of experimental design characteristics that are thought to be clinically relevant and critical to reproducibility in animal studies (e.g., conducting and reporting experiments according to the STAIR and ARRIVE guidelines, respectively). Given that ICH has no current neuroprotective treatments and an ongoing reproducibility crisis in preclinical research, translational design should be considered by investigators. We conducted a systematic review of ICH research from 2015 to 2019 using the PubMed database. Our search returned 281 published manuscripts studying putative neuroprotectants in animal models. Contemporary ICH research predominantly uses young, healthy male rodents. The collagenase model is the most commonly used. Reporting of group sizes, blinding, and randomization are almost unanimous, but group size calculations, mortality and exclusion criteria, and animal model characteristics are infrequently reported. Overall, current ICH neuroprotection research somewhat aligns with experimental design and reporting guidelines. However, there are areas for improvement. Because failure to consider translational design is associated with inflation of effect sizes (and possibly hindered reproducibility), we suggest that researchers, editors, and publishers collaboratively consider enhanced adherence to published guidelines.
Removal of Al, Ba and Mg from industrial wastewater using EAFDS and lime
Authors: Forsido Tedlaye T. , McCrindle Rob I. , Maree Jannie , Monyatsi Lizzy 
Published: June 2020

AbstractWastewater treatment and removal of hazardous metals is imperative for the well-being of living things and the environment. Different methods for the removal of hazardous metals have been proposed and practiced with varying success. In this study, dust slag generated by electric arc furnace is utilized for the removal of aluminium, barium and magnesium from industrial effluent. Slag which is a waste generated during the process of steel production is alkaline by nature. It was able to raise the pH of the acidic effluent to 8.7 removing most of the metals and reducing the amount of commercial alkali required to raise the pH to the target pH of 12.5. EAFDS in conjunction with lime removed 98% of Al, 95.8% of Ba and 99.7% of Mg. The method was simple, efficient and cost-effective since it utilizes a material considered hazardous waste for the treatment.
Case report. Bacteriofagentherapie bij een cystoprostatitis
Authors: van Ginkel Charlotte J. , Davits Rob J. A. M. 
Published: June 2020

SamenvattingBacteriofagentherapie biedt mogelijk een oplossing voor de problemen van antibioticaresistentie. Ze werd toegepast in deze casus van een 71-jarige man met cystoprostatitis op basis van een multiresistente Klebsiella pneumoniae. De patiënt had sterk invaliderende klachten van nycturie en dysurie. Antibiotische behandeling hielp slechts tijdelijk. Behandeling met bacteriofagen, oraal en intravesicaal, resulteerde echter in afname van klachten, met tot nu toe blijvend succes. Het veilig gebruik met positieve resultaten van bacteriofagentherapie werd reeds beschreven in de (urologische) literatuur. De behandeling lijkt veelbelovend. Het opzetten van gerandomiseerde studies is nodig om te onderzoeken of deze therapie een oplossing kan zijn bij de problemen van de huidige toenemende antibioticaresistentie.
Artificial Triterpenoid Fatty Acid Ester Isolated From the Leaves of Phytolacca icosandra L
Authors: Galarraga Elier , Mavares Andersson , Urdaneta Neudo , Rodríguez-Lugo Rafael E. , Amaro-Luis Juan Manuel 
Published: June 2020

Abstract
The methanol extract form the leaves of Phytolacca icosandra L., afforded the unprecedented artificial triterpenoid fatty acid ester 1 derived from the new natural triterpenoid phytolaccagenic acid 3-O-myristate (1a), along with the three known triterpenoids serjanic, acinosolic and phytolaccagenic acid (2 – 4). Their structures were stablished by HR-EI-MS, 1D and 2D NMR techniques. The possible mechanistic formation of 1 is proposed, and the in vitro toxicity of all compounds was assessed using the brine shrimp lethality assay (BSLA).

Graphic Abstract