bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALYSIS OF THE POSSIBLE APPLICATION OF DEAMMONIFICATION TECHNOLOGY IN THE MUNICIPAL WASTEWATER TREATMENT PLANT IN ZABRZE
Authors: PĘCIAK-FORYŚ Grażyna , BARBUSIŃSKI Krzysztof , FILIPEK Krzysztof 
Published: February 2020

Abstract
Due to eutrophication phenomena the modern wastewater plants are obliged to apply highly effective technologies to remove nutrient, i.e. nitrogen and phosphorous, substances. The biological methods to remove nitrogen in the processes of nitrification and denitrifications are successfully used in the main technological line (mainstream). It has been observed, however, that in technical design of activated sludge bioreactor the additional ammonia nitrogen load coming from fermented sludge dewatering effluents was not sufficiently considered. This load, of ca. 20–30% of a total nitrogen inflow, could interrupt the nitrogen removal process. Therefore, the sidestream ammonia nitrogen removal technologies have been widely applied. The operating problems and the ways to solve them in the “Śródmieście” WWTP in Zabrze, resulting from additional nitrogen load, coming from dewatering and thickening effluents, are described in the presented paper. Moreover, preliminary calculations of the DEMON® reactor volume, on the basis of actual nitrogen concentrations in the leachate, in order to implementation deammonification technology in the sidestream on a technical scale were also presented.
Entomopathogenic Fungi And Their Biocenotic Importance
Authors: Zimowska Beata , Król Ewa Dorota 
Published: February 2020

Abstract
Naturally occurring entomopathogens are important regulatory factors of insect populations. Among them, entomopathogenic fungi play a meaningful role. The invasion of insects by parasitic fungi occurs through penetration of the host integument. Death of the host is a result of tissue destruction, exhaustion of nutrients, and the production of toxins. Many recent studies show that entomopathogenic fungi are not only considered as insect pathogens, but also play additional roles in nature, including endophytism, plant disease antagonism, plant growth promotion, and rhizosphere colonization. These newly understood attributes provide possibilities to use fungi in multiple roles. Such additional roles recently-discovered to be played by entomopathogenic fungi provide opportunities for multiple uses of these fungi in integrated pest management strategies. This article reviews the literature currently available on entomopathogenic fungi. It also addresses the possible mechanisms of protection conferred by endophytic fungal entomopathogens and explores the potential use of these fungi as dual microbial control agents against both insect and pathogen pests.
Introduction. 2. Historical and taxonomical notes. 3. Ecological aspects. 4. Use of entomopathogenic fungi. 5. Prospects in integrated pest management. 6. Conclusions
Ferramentas gerenciais utilizadas pelos prestadores de serviços contábeis nas empresas de pequeno e médio porte da região metropolitana de João Pessoa
Authors: Coutinho Anderson Queiroz Henriques , Cruz Vera Lucia , Santos Ramon Rodrigues , Silva Geisa Cassiana Paulino , Morais Rayssa Silva 
Published: February 2020

A Contabilidade Gerencial possui diversas ferramentas que podem dar suporte administrativo às entidades no processo de tomada de decisões. Sendo assim, o presente estudo teve como objetivo fazer um levantamento sobre a utilização dessas ferramentas por parte das empresas prestadoras de serviços contábeis responsáveis pela contabilidade das Pequenas e Médias Empresas situadas na região metropolitana de João Pessoa. O método utilizado nesta pesquisa foi o bibliográfico e descritivo. Com o intuito de obter as informações necessárias para condução do estudo, recorreu-se a um questionário semiestruturado, com perguntas fechadas e abertas, aplicado aos responsáveis das 31 empresas contábeis em um universo de 135 cadastradas e ativas no Conselho Regional de Contabilidade da Paraíba em 2013. Foi verificado o conhecimento e a aplicação das ferramentas gerenciais por parte dos escritórios - os resultados indicam que os contadores conhecem a maioria das ferramentas, porém não as aplicam na mesma proporção em seus clientes. Este quadro foi parcialmente justificado quando responderam na pesquisa que o momento da implantação é considerado o de maior dificuldade para a aplicabilidade. Dentre as ferramentas gerenciais, o Fluxo de Caixa e o Planejamento Estratégico foram as mais citadas quanto ao conhecimento e a aplicabilidade, já o certificado do PROCEM e o Downsizing foram os menos mencionados.
Advances in Nanoparticles as Anticancer Drug Delivery Vector: Need of this Century
Authors: Ali Imran , Mukhtar Sofi D. , Ali Heyam S. , Scotti Marcus T. , Scotti Luciana 
Published: February 2020

Background:
Nanotechnology has contributed a great deal to the field of medical science. Smart drugdelivery
vectors, combined with stimuli-based characteristics, are becoming increasingly important. The use of
external and internal stimulating factors can have enormous benefits and increase the targeting efficiency of
nanotechnology platforms. The pH values of tumor vascular tissues are acidic in nature, allowing the improved
targeting of anticancer drug payloads using drug-delivery vectors. Nanopolymers are smart drug-delivery vectors
that have recently been developed and recommended for use by scientists because of their potential targeting
capabilities, non-toxicity and biocompatibility, and make them ideal nanocarriers for personalized drug delivery.

Method:
The present review article provides an overview of current advances in the use of nanoparticles (NPs) as
anticancer drug-delivery vectors.

Results:
This article reviews the molecular basis for the use of NPs in medicine, including personalized medicine,
personalized therapy, emerging vistas in anticancer therapy, nanopolymer targeting, passive and active targeting
transports, pH-responsive drug carriers, biological barriers, computer-aided drug design, future challenges and
perspectives, biodegradability and safety.

Conclusions:
This article will benefit academia, researchers, clinicians, and government authorities by providing a
basis for further research advancements.
Bentonite Clays for Therapeutic Purposes and Biomaterial Design
Authors: Srasra Ezzeddine , Bekri-Abbes Imene 
Published: February 2020

Background:Bentonite is a natural clay composed mainly of montmorillonite with other associated minerals such as feldspar, calcite and quartz. Owing to its high cation exchange, large surface area and ability to form thixotropic gels with water and to absorb large quantities of gas, it presents a large medicinal application.Objective:This review focuses on the promising potential of bentonite clays for biomaterial design and for therapeutic purposes.Methods:PubMed, ACS publications and Elsevier were searched for relevant papers. We have also evaluated the references of some pertinent articles.Results:Healing properties of bentonite are derived from the crystalline structure of the smectite group, which is composed of two octahedral alumina sheets localized between two tetrahedral silica sheets. This structure is behind the ability to intercalate cationic bioactive agents and undergoes interaction with various toxic species and exchanging in return species such as Fe3+, Cu2+, Al3+ Ca2+ or Na+, presenting antibacterial activity and providing essential minerals to the body. Furthermore, due to to its layered structure, bentonite has wide application for the design of biomaterials providing, thus, the stability of bioactive agents and preventing them from aggregation.Conclusion:Numerous publications have cited bentonite extensive applications as an alternative and complementary treatment for numerous health conditions as a detoxifying agent and for the preparation of several bionanocomposites.
Utilization of Jackfruit Peel as a Low-cost Adsorbent for the Removal of Methylene Blue Dye from Synthetically Polluted Water
Authors: Ahmed Mohsina , Nasar Abu 
Published: February 2020

Background:
Due to an abrupt increase in the contamination of freshwater systems by
dye-containing wastewater, there is an urgent need to find robust and greener adsorbents for the elimination
of dyes from the contaminated water. As the dyes not only change the appearance of water
but are also a cause of many serious problems, which can be some time mutagenic and carcinogenic.

Methods:
This research paper is based on the use of adsorbent made from the peel of jackfruit (POJ). The adsorbent derived from agriculture waste was low cost and efficient for the elimination of methylene blue (MB) dye from aqueous media. Batch adsorption experiments were accompanied by varying the pH of the solution, contact time, POJ dosage, and initial MB concentration.

Results:
It was seen that adsorption of MB onto Jackfruit peel adsorbent follows pseudo-second-order (PSO) kinetics and Langmuir isotherm with maximum biosorption capacity (qm) of 232.55 mg/g. The thermodynamic study revealed that the adsorption was spontaneous, endothermic, and associated with the rise in entropy.

Conclusion:
In view of the low-cost and promising adsorption efficiency, the present investigation submits that that POJ is novel and economically feasible adsorbent for the removal of MB from aqueous solutions.
Focus. Ontwikkelingen in het Jeremiaonderzoek
Authors: Peels H.G.L. 
Published: February 2020

Hindy Najman en Konrad Schmid (red.), Jeremiah’s Scriptures: Production, Reception, Interaction, and Transformation [Supplements to the Journal for the Study of Judaism 173] (Leiden/Boston: Brill, 2017) xii + 633 p., € 186,00 (ISBN 9789004320246). Jack R. Lundbom, Craig A. Evans en Bradford A. Anderson (red.), The Book of Jeremiah: Composition, Reception, and Interpretation [Supplements to Vetus Testamentum 178] (Leiden/Boston: Brill, 2018) xix + 545 p., € 154,00 (ISBN 9789004373266).
REVITALISASI TEATER TRADISIONAL “KETOPRAK”
Authors: Murdiyastomo HY. Agus 
Published: February 2020

Di Era globalisasi yang diikuti perkembangan tekhnologi informasi seperti sekarang ini, seolah negara tanpa batas, budaya asing dapat begitu saja masuk dan mempengaruhi masyarakat luas. Hal seperti ini sangat besar pengaruhnya terhadap tumbuhkembangnya seni tradisi termasuk seni ketoprak. Seni tradisi dianggap ketinggalan jaman, dan tidak menarik, sehingga ditinggalkan penonoton. Oleh sebab itu kegiatan penelitian ini bermaksud untuk merunut masa lalu seni ketoprak, atau dengan kata lain merunut lahirnya seni ketoprak dan perkembangannya hingga mencapai puncaknya di tahun 1980-an awal. Setelah itu satu persatu kelompok-kelompok seni ketoprak profesional yang dikenal dengan ketoprak tobong tumbang. Begitu pula kelompok-kelompok ketoprak amatir yang ada di kalangan masyarakat luas, mereka tidak lagi aktif, alias mati suri. Penelitian ini bertujuan mencari tahu apakah seni ketoprak masih diminati oleh masyarakat, khususnya di DIY. dan mengembangkannya menjadi atraksi yang bukan sekedar tontonan tetapi juga tuntunan, mengingat atraksi ini dapat disisipi dengan pesan moral.
Governabilidade e descentralização
Authors: Dowbor Ladislau 
Published: February 2020

O governo, principalmente em países desenvolvidos, administra hoje metade do produto social. Por exemplo: a participação percentual dosgastos do governo do Reino Unido, há 100 anos, era de 10% do PIB ou PNB. Hoje é de 48%. A progressão da participação do Estado é grande e significativa. Apresentar essa informação é importante porque segmentos da sociedade querem um Estado "pequeno e eficiente", justificando um processo caótico de privatizações. A realidade com a qual temos que trabalhar para enfrentar os processos de mudanças é a de um Estado amplo, mas que tem que funcionar de forma diferente.
Articulação entre o Executivo e o Legislativo: o processo orçamentário
Authors: Nacional de Administração Pública Fundação Escola 
Published: February 2020

A análise do processo orçamentário da União encontra-se em fase inicial, procedendo-se atualmente ao levantamento e seleção de bibliografia, treinamento de equipe e definição detalhada do cronograma e produtos. Sua conclusão está prevista para setembro de 1994.
Papel e ação do Estado no comércio exterior
Authors: Sosa Roosevelt Baldomir 
Published: February 2020

O texto propõe a reestruturação da alfândega brasileira como instituição independente da Secretaria da Receita Federal, visando equipar o Estado com o canal institucional apropriado a uma adequada política de comércio exterior. A premissa básica é a edição de uma lei que estabeleça o modo de ação de uma aduana moderna, com a desobstrução dos canais logísticos, e que propicie um novo enfoque nas relações do Estado com os agentes econômicos.
Reforma do Estado e pesquisa nas telecomunicações no Brasil: um estudo sobre o Centro de Pesquisas e Desenvolvimento — CPqD
Authors: Menardi Fabrício Benedito , Costa Maria Conceição da 
Published: February 2020

Num cenário de mudanças tecnológicas dinâmicas e num contexto de discussão de Reforma do Estado, o setor de telecomunicações é um locus privilegiado de observação dessas transformações. Partindo dessas duas constatações, este paper analisa o papel do Centro de Pesquisas e Desenvolvimento — CPqD, que nesta última década deixou de ser um centro gerador de tecnologia para se transformar num centro prestador de serviços.
Da burocracia à ad hocracia
Authors: Goulart Flavio A. de Andrade , Cunha Rosani Evangelista da 
Published: February 2020

As organizações de saúde são sempre organizações complexas, que realizam seus objetivos por intermédio das funções de gestão, nome que se dá ao conjunto de atributos de gestão e de gerência relacionados ao âmbito dos sistemas e dos serviços de saúde, seja no plano político, técnico-finalístico ou técnico-administrativo. Funções de gestão e práticas de saúde devem estar contempladas em uma estrutura de gestão. A estrutura é algo mais complexo do que um simples organograma. O entendimento da dinâmica organizacional e de sua adaptação às organizações concretas, segundo o referencial do autor canadense, H. Mintzberg, é fundamental para se propor estruturas adequadas às novas funções dos órgãos gestores em saúde. A grande exigência para a organização de saúde contemporânea é a de maior flexibilidade, com autonomia de trabalho, descentralização e gestão democrática. O processo de trabalho deve apoiar-se em projetos, com metas, prazos e recursos bem definidos, reunindo saberes e pessoas de áreas e especialidades diferentes, sob mandatos que podem não ser permanentes, mas designados especificamente para as necessidades.
Planejamento estratégico no setor público: uma experiência no Palácio do Planalto
Authors: Marcelino Gileno Fernandes 
Published: February 2020

Este trabalho descreve e analisa uma experiência pioneira de desenvolvimento de um processo de planejamento e administração estratégica no Palácio do Planalto, centro de decisões do Poder Executivo. O processo, que se iniciou em março de 1995, primeiro ano de mandato do atual presidente, prossegue até os dias de hoje, como exemplo raro de continuidade administrativa na Administração Pública Federal. Nestes quatro anos de experiência, a Secretaria-Geral da Presidência da República (SGPR) alcançou alguns resultados concretos: 98,5% de execução orçamentária (um recorde na Esplanada dos Ministérios), 91,3% das ações, metas, projetos e programas executados, redução do pessoal e estrutura administrativa em mais de 50% e uma economia estimada em mais de R$ 100 milhões durante os quatro anos. Este estudo descreve como tudo isso foi alcançado
Contribuições do Programa Bolsa Família para a gestão das políticas sociais
Authors: Lício Elaine Cristina 
Published: February 2020

O artigo destaca as principais contribuições do Programa Bolsa Família para a gestão das políticas sociais brasileiras, sob a perspectiva da organização do aparato estatal para o enfrentamento da pobreza e da desigualdade social. Após reconstituir historicamente a trajetória das políticas de combate à pobreza, apresenta o modelo de gestão do programa, destacando seus principais aspectos inovadores. Em seguida, especifica suas contribuições mais importantes, como o maior foco na população pobre e o fortalecimento do federalismo cooperativo para implementação articulada das iniciativas voltadas às pessoas em situação de pobreza. Por fim, identifica alguns desafios que permanecem para o programa, no que se refere à ampliação do acesso da população pobre às políticas sociais universais.Palavras-chave: federalismo; intersetorialidade; políticas sociais
EFFECTIVENESS AND SAFETY ASSESSMENT OF FIXED DOSE COMBINATION OF NON-STEROIDAL ANTIINFLAMMATORY DRUGS PRESCRIBED FOR ORTHOPEDIC PATIENTS
Authors: SOLANKI NILAY , GOR ALPA , PARMAR BIRAJ 
Published: February 2020

Objective: Many Fix Dose Combinations (FDCs) being introduced in India are usually irrational. The most pressing concern with irrational FDCs is that they expose patients to unnecessary risk of adverse drug reactions, for instance, pediatric formulations of nimesulide+paracetamol. Despite their wide clinical use, their gastro-intestinal toxicity is a major limitation. The aim of the present work was to evaluate the efficacy and safety of FDCs in non-steroidal anti-inflammatory drugs in the orthopedic department at a tertiary care teaching hospital. To study the effectiveness and safety parameters of fixed-dose combinations of Non-Steroidal Anti-inflammatory Drugs.
Methods: This prospective, observational study was conducted among 150 out-patients of the orthopedic ward over a period of July 2013 to December 2013(Each combination with 50 patients). Three fixed-dose combinations utilized were paracetamol+diclofenac, paracetamol+ibuprofen and paracetamol+nimesulide. The effectiveness was analyzed by using Visual Analogue Scale (VAS) and Disease Activity Scale (DAS) and the safety criteria were analyzed by using the WHO probability scale and Naranjo scale. 150 orthopedic patients attending Out Patient Department were included. 50 participants for each of the combinations of fixed-dose combination (FDCs) of NSAIDs.
Results: Out of 150 patients 33 patients developed adverse effects, and 17(51.51%) adverse effects due to the combination of Paracetmol+Nimuselide, 11(33.34%) adverse effects due to the Paracetamol+Ibuprofen and 5 (15.15%) were due to the combination of Paracetamol+Diclofenac. The maximum effectiveness (3.55±0.208) showed in the combination of paracetamol+diclofenac compared to the other two combinations.
Conclusion: It was concluded from this study that the effectiveness and safety profile of PCM+DICLO is better than the other two FDCs.
DESIGN AND DEVELOPMENT OF RILPIVIRINE NANOPARTICLE CONTAINING CHITOSAN USING IONIC GELATION METHOD FOR HIV INFECTIONS
Authors: PATEL MONTUKUMAR , PATEL NIRAV V. , PATEL TEJAS B. 
Published: February 2020

Objective: The primary objective of the current research was to prepare rilpivirine loaded Nanoparticles containing Chitosan using the ionic gelation method for HIV infections.
Methods: The nanoparticles of rilpivirine were prepared using the ionic gelation technique. Further, nanoparticles were characterized by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and in vitro drug release.
Results: The optimized nanoparticles were found with a particle size of 130.30±5.29 nm (mean±SD) and entrapment efficiency (% EE) of 77.10±0.50%. Scanning electron microscopy technique exposed spherical particles with uniform size. It was observed that the nanoparticles created showed the absence of the crystalline nature of the drug and its switch to the amorphous state. Results showed that more than 45% of the pure drug is released in 50 min and after 90 min almost about 95% of the drug is released.
Conclusion: The research study concluded that the in vitro release profile of nanoparticles was found to be sustained up to 24 hr. Sustained release of the rilpivirine could improve patient obedience to drug regimens, growing action effectiveness.
ASSESSING COSMECEUTICALS PROPERTIES OF SOME MACROFUNGI FOR IMPROVED SKINCARE
Authors: SARASWAT AKASH , MATHUR PURVI , SANYAL DOYELI 
Published: February 2020

Objective: This study has investigated cosmeceutical properties namely, antibacterial, sun protection factor and total phenolics contents of some selected macrofungi. The studies were conducted on five reference cultures collected from Indian type culture collection center (IMTEC, Chandigarh, India) and five isolates collected from TERI-Deakin Nano Biotechnology Centre facility at TERI Gram, Gurugram, India.
Methods: The cosmeceutical properties of the crude extracts from selected macrofungi were analyzed using standard bioassay techniques. Antibacterial activity was analyzed against Staphylococcus epidermidis, Escherichia coli, Micrococcus luteus, Bacillus megaterium, Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii using Agar well diffusion method. The sun protection factor was estimated and calculated using the Mansur equation. Free radical scavenging activity using DPPH was performed to assess the antioxidant activity of the extracts.
Results: Ethyl acetate extracts of the broth from P. florida and TERI-G1 cultures showed a broad-spectrum antibacterial activity against S. epidermidis, E. coli, M. luteus and B. megaterium. Ethyl acetate extracts of the broth from TERI-G3 showed the highest SPF activity of 34.02 at 200 µg. ml-1 concentration. Ethyl acetate extract of the broth from F. velutipes, P. florida, P. ostreatus, and TERI-G1 showed comparable antioxidant activity of 66.86%, 79.51%, 82.02%, and 69.58% respectively when compared to ascorbic acid (85.83%) and quercetin (83.09%) taken as positive control in the study and their total phenolic contents were found to be 6.93, 43.68, 20.88 and 13.77 Gallic acid equivalent (GAE) per gram. The minimal inhibitory concentration of F. velutipes, P. florida, P. ostreatus, and TERI-G1 was found to be 3552.89 µg. ml-1, 1250 µg. ml-1, 2418.9 µg. ml-1 and 3219 µg. ml-1 respectively.
Conclusion: The work is in progress to identify and characterize TERI-G1and TERI G3 cultures. Further studies on the anti-inflammatory, anti-tyrosinase, elastase inhibition properties of the cultures will be assessed to identify potential cosmeceutical active ingredients with promising applications in cosmeceutical products.