bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asthma Phenotyping Via Multiplex Detection of Cytokines on an Electrochemical Sensor
Authors: Churcher Nathan , Prasad Shalini 
Published: December 2024

Asthma, a complex and diverse lung condition, is typically associated with chronic airway inflammation. Asthma classification has traditionally relied on clinical symptoms and treatment response. As our understanding of asthma’s heterogeneity grows, phenotyping has become a focus. Cytokines, essential chemical messengers in the immune system, play a pivotal role in the mediation of chronic diseases. They facilitate communication between immune cells and directly impact inflammation. Various cytokines have been implicated in asthma pathogenesis. Leveraging cytokines for asthma phenotyping is valuable, as identifying and quantifying these inflammatory mediators can lead to more precise, targeted treatments. To achieve this, we have developed a customizable electrochemical platform for multiplexed detection of select cytokines for non-invasive cytokine detection in saliva. This platform rapidly detects cytokines within physiological ranges and will aid physicians in asthma phenotyping and treatment planning especially for severe asthmatics.
The detection platform leverages subtle changes in impedance at the electrode-electrolyte interface as a function of the chemical interaction between specific antibody-antigen interactions to establish a calibration dose response curve. The platform’s capability to detect and quantify the cytokines in human saliva is demonstrated through spike and recovery experiments.
Electrochemical Simultaneous Determination of Biohazardous Polyphenols Using a Novel Mesoporous Nickel-Modified Carbon Sensor
Authors: Xue Yilei , Noroozifar Meissam , Kerman Kagan 
Published: December 2024

The widespread occurrence of endocrine disruptor compounds in wastewater has garnered significant attention owing to their toxicity, even at low concentrations, and their persistence in the water body. Among various analytical techniques, electrochemical sensors have become the preferred tools for the environmental monitoring of water pollutants due to their low cost, rapid detection, high sensitivity, and selectivity [1,2]. In this study, the mesoporous Ni (MNi) material was synthesized with an innovative method using Pluronic™ F-127 as a soft template and applied as a modifier for the simultaneous electrochemical sensing of hydroquinone (HQ), catechol (CC), bisphenol A (BPA), and bisphenol S (BPS) [3]. MNi with high porosity efficiently enhanced the redox-active surface area and conductivity of the glassy carbon electrode contributing to a significantly improved sensitivity in the detection of target chemicals. The pore size and surface area of MNi were estimated based on atomic force microscopy. The limit of detection for HQ, CC, BPA, and BPS was determined to be 5.3, 5.7, 5.6, and 61.5 nM, respectively. The electrochemical sensor presented in this study holds promise as a platform for developing portable and miniaturized tools offering the rapid and sensitive detection of these biohazardous polyphenolic compounds in environmental water samples.
References

G. Hanharan et al., J. Environ. Monit. 2004, 6, 657-664.

S. Sultana et al., J. Electroanal. Chem. 2021, 899, 115644.

Y. Xue et al., Chemosphere 2023, 342, 140003.
(Digital Presentation) Electrochemical Detection of Analgesic Acetaminophen Using Sensor Comprised of Low-Cu2+-Doped CoFe2O4 Nanoparticles from Glycerol-Assisted Synthesis
Authors: Alfonso González Jose Guillermo , Granja Claudia Patricia , Morales Jimmy , Dector Andrés 
Published: December 2024

This work devised a simple glycerol-assisted synthesis of a low-Cu2+-doped CoFe2O4 and the elec-trochemical detection of acetaminophen (AC). During the synthesis, several polyalcohols were tested, indicating the efficiency of glycerin as a cosolvent, aiding in the creation of electrode-modifier nanomaterials. A duration of standing time (eight hours) before calcination produces a decrease in the secondary phase of hematite. The synthesized material was used as an electrode material in the detection of AC. In acidic conditions (pH 2.5), the limit of detection (LOD) was 99.4 nM, while the limit of quantification (LOQ) was found to be (331 nM). The relative standard deviation (RSD), 3.31%, was computed. The enhanced electrocatalytic activity of a low-Cu2+-doped CoFe2O4-modified electrode Cu0.13Co0.87Fe2O4/GCE corresponds extremely well with its resistance Rct, which was determined using the electrochemical impedance spectroscopy (EIS) technique and defined its electron transfer capacity. The possibility of a low-Cu2+-doped CoFe2O4 for the electrochemical sensing of AC in human urine samples was studied. The recovery rates ranging from 96.5 to 101.0% were obtained. These findings suggested that the Cu0.13Co0.87Fe2O4/GCE sensor has outstanding practicability and could be utilized to detect AC content in real complex biological samples.
References
Alfonso-González, J.G.; Granja-Banguera, C.P.; Morales-Morales, J.A.; Dector, A. A Facile Glycerol-Assisted Synthesis of Low-Cu2+-Doped CoFe2O4 for Electrochemical Sensing of Acetaminophen. Biosensors 2023, 13, 997
(Keynote) High Power Batteries Enabled by Disordered Rocksalt Anodes
Authors: Liu Ping 
Published: December 2024

Batteries with exceptional charge and discharge rates and cycle life can bridge the gap between high-energy-density batteries and supercapacitors. In traditional lithium-ion batteries, the limiting electrode is usually the carbon anode. Fast charging, for example, leads to deposition of lithium metal which triggers life and safety issues. Oxide anodes with higher operating potentials have been considered, e.g., lithium titanium oxide, titanium niobium oxide, to name a few.
In recent years, we have been developing lithium vanadium oxide as an anode. Li3V2O5 (LVO) has a disordered rocksalt (DRS) structure. When 2 moles of lithium are inserted into this structure, the volume change is about 5.5%. The cubic structure, however, indicates that the linear change is only 1.8%. The material has an operating potential of 0.6 V vs Li/Li+, thus virtually eliminating the possibility of lithium plating. Lithium-ion cells pairing LVO with 4V oxide cathodes have demonstrated thousands of stable cycles and can be charged at a rate as high as 20C (Nature, 2020, 63). To further lower the potential (which translates to higher energy density for a cell), we have investigated the possibility of doping with Mg. Both theoretical and experimental evidence suggest that the DRS structure is preserved. More interestingly, we have found that the electrode potential can indeed be lowered while the fast charging and long life qualities are preserved.
We have further extended this DRS design principle to sodium ion systems. Insertion of sodium into V2O5 results in the formation of a DRS structure, analogous to the case of lithium. Na3V2O5 (NVO) is found to accept two mole of Na reversibly within the DRS structure. Pairing NVO with a sodium vanadium phosphate cathode forms a sodium ion all vanadium battery. This battery has shown exceptional rate capabilities during both charging and discharging, with great potential for applications in power conditioning systems and grid storage.
Role of Lattice Flexibility on Electrochemical Ion Insertion: Structural Dynamics in WO3 vs WO2.9
Authors: Musico Vincenzo , Holzapfel Noah , Tsai Wan-Yu , Balke Nina , Augustyn Veronica 
Published: December 2024

The demand for high energy and high power energy storage devices drives the search for electrode materials that can exhibit high capacities and fast kinetics. One strategy to achieve these properties is through the use of ion insertion-type electrodes that can undergo at least 1 e- transfer (for high specific capacity) with little structural change (for fast kinetics). To investigate this strategy, we examined the ion insertion behavior of WO3 with the related oxygen deficient Magnéli phase, WO2.9. WO2.9 contains crystallographic shear planes, which are planes of edge-sharing WO6 octahedra within a corner-sharing framework. The presence of crystallographic shear planes is proposed to increase ion insertion kinetics because they decrease the lattice flexibility of the material.
To test this hypothesis, we performed cyclic voltammetry in aqueous and non-aqueous electrolytes as well as galvanostatic intermittent titration technique (GITT) and galvanostatic charge discharge (GCD) to study the kinetics H+ and Li+ insertion into WO3 and WO2.9. In acidic electrolytes, WO3 inserts more H+, achieving a capacity of 41 mAh/g, compared to WO2.9 which has a capacity of 17.5 mAh/g. In non-aqueous electrolytes, WO2.9 can insert more Li+ than WO3, achieving a capacity of 127 mAh/g at a rate of C/10 compared to WO3, which has a capacity of 100 mAh/g. During Li+ insertion, WO2.9 exhibits a diffusion coefficient of 10-8 cm2/s compared to WO3, which has a diffusion coefficient of 10-10 cm2/s. To measure the lattice flexibility during H+ insertion, we performed operando AFM experiments. We measured the local change in thickness of tungsten oxide electrodes in aqueous acidic electrolyte during electrochemical cycling. We observe that WO2.9 undergoes less deformation during proton insertion and de-insertion than WO3. However, it undergoes higher deformation per e-/formula unit. To investigate the lattice flexibility and structural changes during Li+ insertion and de-insertion, we performed in situ XRD and observed that WO2.9 undergoes a small volumetric contraction of < 0.6% during the insertion of 1.14 Li+ per formula unit. This study reports the benefits and tradeoffs of utilizing non-stoichiometric oxides like WO2.9 as electrodes for insertion-type high power energy storage.
New Applications of Knudsen Effusion Mass Spectrometry (KEMS) for Gas Evolution Analysis in Lithium-Ion Batteries
Authors: Buch Jonas , Tahir Uzair , Markus Torsten , Henriques David 
Published: December 2024

Kems4Bats, a new research group initiated under the BMBF's NanoMatFutur framework at Hochschule Mannheim, employs both established and innovative experimental methods to analyze thermal and gaseous emissions in lithium-ion batteries. Operating from a state-of-the-art laboratory equipped with advanced instrumentation, the group examines how variations in electrode materials and particle dimensions influence diffusion and gas generation. Key research focuses include studying diffusion processes, the formation of solid electrolyte interfaces, and the impacts of fast charging on battery aging. Significant achievements of Kems4Bats include the development of a new instrument based on the KEMS (Knudsen effusion mass spectrometry) method, which enables precise, real-time in-situ measurements of gas evolution in lithium-ion batteries. Moreover, this device allows for highly accurate measurements of vapor pressures, particularly for organic substances with high vapor pressures, such as electrolyte solvents. Additionally, the group has established a battery production line, enhancing the safety and effectiveness of these energy storage systems.
The improvement and detailed study of lithium-ion batteries are essential for advancing energy storage technologies. Understanding how gases evolve within these batteries during their formation, operational cycles, and aging is crucial for enhancing their performance and safety. Historically, Knudsen Effusion Mass Spectrometry (KEMS) has been an effective method for measuring the temperature-dependent vapor pressures of various materials, both organic and inorganic. This technique aids in calculating important thermodynamic properties. This study expands the application of KEMS to investigate gas evolution in lithium-ion batteries, marking a significant development in battery diagnostics.
A unique prototype was developed to modify the KEMS approach, allowing for accurate monitoring of gas species evolution in lithium-ion batteries. This innovation not only provides detailed insights into the types and quantities of gases produced at different stages of the battery lifecycle but also broadens the traditional boundaries of KEMS measurements. Our modified system allows for the analysis of substances with high vapor pressures, such as electrolyte components, which were previously challenging to study due to methodological limitations.
The results of this research shows the complex patterns of gas formation in lithium-ion batteries, providing essential insights for improving battery design and establishing higher safety standards. This research not only advances the field of battery technology but also highlights the adaptability of KEMS as a powerful tool in materials science.
MnO2-Conductive Nanodiamond Composite Electrode for High Energy Density Aqueous Capacitor
Authors: Imai Kazuto , Kondo Takeshi 
Published: December 2024

Electric double-layer capacitors (EDLC) have the advantage of faster charge-discharge rates and superior cycle life compared to rechargeable batteries, but have the disadvantage of low energy density. In order to increase energy density of EDLCs, it is necessary to increase cell voltage and specific surface area. Another possible strategy to enhance the energy density is combination with redox-active compounds to form pseudocapacitor. We have developed boron-doped nanodiamond (BDND) as a novel electrode material for EDLC, which has a wide potential window in aqueous electrolytes, high voltage application capability, and large specific surface area. The aim of this study is to fabricate a pseudocapacitor by compositing BDND with MnO2 in order to further improve the energy density.
BDND was prepared by depositing a boron-doped diamond (BDD) layer on the surface of nanodiamond particles by microwave plasma CVD followed by heat treatment in air to minimize the sp2 carbon impurities. BDND ink was prepared by mixing BDND and ethanol. The BDND ink was then applied on a glassy carbon current collector, and MnO2-BDND electrodes were prepared by electrodeposition of MnO2 on the BDND using constant potential electrolysis in 0.6 M MnSO4/0.8 M H2SO4 at +1.25 V vs. Ag/AgCl. Cyclic voltammetry (CV) in 1 M Na2SO4 was used to evaluate the electrochemical properties of the MnO2-BDND electrode.
MnO2-BDND electrodes were prepared with various MnO2 deposition times of 1, 3, 5, and 15 min. It was found from the CV current density that the MnO2-BDND prepared at a deposition time of 3 min exhibited the largest capacitance of 43.5 F/g, while the capacitance of unmodified BDND electrode was 14.5 F/g. Therefore, MnO2 deposition time of 3 min was determined to be the optimum condition; the reason for the decrease in the CV current of MnO2-BDND with a deposition time of 5 and 15 min is considered to be due to excess amount of MnO2 with poor conductivity on the electrode surface. Energy density of the MnO2-BDND/1 M Na2SO4 system was calculated with a cell voltage of 1.5 V to be 21.2 Wh/kg, which was greater than that of the BDND/1 M Na2SO4 system (9.1 Wh/kg). Therefore, BDND-based high energy density aqueous capacitor is expected to be fabricated by the combination with MnO2.
Effect of Cell Diameter on Charge-Discharge Performance in All-Solid-State Batteries
Authors: Kamei Ayaka , Zhong Chengchao , Shimoda Keiji , Okazaki Ken-ichi , Orikasa Yuki 
Published: December 2024

All-solid-state batteries are expected to offer high safety and energy density. The discovery of solid electrolytes with high ionic conductivity has accelerated development toward practical applications. However, high performance has only been demonstrated in small cells at the laboratory level and has not yet been introduced in larger all-solid-state batteries that can be used in electric vehicles and energy storage systems. To the best of our knowledge, no studies have been reported on all-solid-state batteries when large cells are used. To elucidate the factors required for large-scale all-solid-state batteries, we fabricated all-solid-state battery cells with various diameters and compared their charge-discharge performance.
Composite electrode was prepared by mixing the cathode active material Nb-coated LiNi1/3Mn1/3Co1/3O2, the solid electrolyte Li6PS5Cl, and the conductivity aid acetylene black in a weight ratio of 1:1:0.1 in an argon atmosphere. In-Li alloy was used for the counter electrode. Electrodes and electrolytes were placed in ceramic tubes with inner diameters of 10 and 30 mm with a fabrication pressure of 188 MPa and a stack pressure of 40 MPa. Galvanostatic charge-discharge measurements were performed between 2.0 and 4.0 V. AC impedance measurements were also carried out.
The initial discharge capacities of the cells with the diameters of 10 and 30 mm were both 140 mA h g-1 at a 0.1C rate. From the test of the rate capability, no clear difference was observed between the two cells. Nyquist plot from the AC impedance measurements exhibited one semicircle assigned to charge transfer resistance. The area specific resistance also did not show the difference in the cell diameter. These results imply that the size of the cell diameter does not affect the charge-discharge performance in cells capable of holding high pressures.
Controlling SnOx Stoichiometry via ALD Deposition on Cu Current Collectors: Investigating Stability and Reversibility Enhancement in Lithium Metal Batteries
Authors: Lee Dawon , Chung Roy Byungkyu 
Published: December 2024

Recent advancements in battery technology have led to the emergence of various types of secondary batteries with higher capacities to meet increasing demands. Among these, research on Lithium metal batteries (LMBs) with high capacity potential is actively pursued. However, LMBs face stability issues due to dendrite formation and low reversibility in Li plating-stripping processes. To address these challenges, we have modified the surface of Cu current collectors with lithiatable material, SnOx, to inhibit dendrite formation, enhance the stability and reversibility of LMBs. Furthermore, SnOx films reduce the overpotential of Li and enable stable Solid Electrolyte Interphase (SEI) formation. Therefore, they enhance the reversibility of Li plating/stripping processes. SnOx films were deposited via Thermal Atomic Layer Deposition (ALD) at 200°C with a thickness of 20nm. We have already reported the effectiveness of SnOx in enhancing the efficiency and stability of LMBs.[1] Therefore, in this study, we conducted research on the variation in characteristics of LMBs resulting from the control of stoichiometry in this lithiatable SnOx. Stoichiometry was adjusted through two methods. One method involved post-deposition heat treatment, where treatments were conducted at 400°C for one hour under H2 (H2 4%, Ar 96% gas) and N2 atmospheres. Additionally, we adjusted the injection time of H2O, the reactant in ALD, varying it from 1 to 3sec to create an oxygen deficient environment, and analyzed each characteristic accordingly. We will present our findings on the effect of SnOx stoichiometry on the performance and stability of LMBs.
[1] Kim, Junghwan, et al. "Homogeneous Li Deposition guided by Ultra-thin Lithiophilic Layer for Highly Stable Anode-free Batteries." Energy Storage Materials (2023): 102899.

Figure 1
(General Student Poster Award Winner, 2nd Place) Understanding the Unique Phase Evolution of Prussian White Cathodes Mediated by the Intrainteraction in Hexacyanometallate Complexes
Authors: Lee Ju-Hyeon , Bae Jin-Gye , Kim Min Sung , Heo Jeong Yeon , Lee Hyeon Jeong , Lee Ji Hoon 
Published: December 2024

Transition metal–based Prussian whites (TM-PWs), consisting of a cyanide anion ((–C≡N–)−) and TM cations in an alternative manner, have a general chemical formula of AxTMm+TMn+(CN)6. PWs are characterized by the TM electronic states that exclusively adopt low spin (LS) toward the C atom and high spin (HS) toward the N atom through the hybridized covalent bonding in the TM–C≡N–TM unit. This property would significantly affect the phase transition behavior upon the release and storage of carrier ions; however, there have been only few studies on their associated features.
In this talk, TM-PWs with different HS TM ions (Fe, Co, and Ni) were synthesized via co-precipitation and the phase transition behavior controlled by the π electron interaction between the cyanide anions and TM ions during battery operations was investigated. In situ X-ray diffraction and X-ray absorption fine structure analyses reveal that the combined effect of π bonding between metal and ligand effectively controls the bond length of the TM–C≡N–TM unit, thus influencing the lattice volume of TM-PW cathodes during the charge/discharge process. This study presents a comprehensive understanding of the structure–property relationship of the TM-PW cathodes involving π electron interactions during battery operations.
Compatibility of LiPON with Different Current Collector Materials for Anode-Free Configuration
Authors: Lopez Pazos Elena , Nobili Luca , Magagnin Luca 
Published: December 2024

The current development of microelectronics requires mature micro energy storage devices. Such devices include, among others, micro batteries. The working principle of such micro batteries does not differ from traditional batteries. However, there are some particular aspects that distinguish them. The first one is that organic liquid electrolytes should be avoided due to their flammability and risk of leakage. Additionally, a great attention must be paid to the energy density of the included materials, since the final aim is the miniaturization [1]. In this sense, the use of thin film deposition techniques becomes crucial for micro batteries fabrication [2,3]. Among these techniques, sputtering constitutes an interesting choice, due to the possibility it offers to transfer the composition of a source target material to a substrate. As a result, thin compact layers with a well-controlled thickness can be obtained.
Regarding the solid-state electrolyte, LiPON is an interesting candidate due to the stability it reportedly offers for lithium plating-stripping [4]. A stable lithium cycle is fundamental for its use as metallic lithium anode or, taking a step further, for an anode-free configuration. Indeed, such king of configuration allows a great degree of device compactness, which is convenient when the miniaturization prosecuted [5].
This works aims at shed some light into the compatibility of LiPON thin films with different current collector materials. Sputtered LiPON thin films have been deposited in contact with different metals, and the produced samples have been characterised with electrochemical techniques such as Charge-Discharge, combined with materials characterization ones such as SEM. The obtained results have allowed to individuate how the plating-stripping of lithium is sustained by LiPON coupled with the different materials.

1]

L. Y. e. al, "On-Chip Batteries for Dust-Sized Computers," Advanced Energy Materials, vol. 12, p. 2103641, 2022.

[2]

B. J. Neudecker, N. J. Dudney and J. B. Bates, ""Lithium‐Free" Thin‐Film Battery with In Situ Plated Li Anode," J. Electrochem.
Soc., vol. 147, no. 517, 200.

[3]

T. Yamamoto, H. Iwasaki, Y. Suzuki, M. Sakakura, Y. Fujii, M. Motoyama and Y. Iriyama, "A Li-free inverted-stack all-solid-state thin film battery using crystalline cathode material," Electrochemistry Communications, vol. 105, 2019.

[4]

P. Albertus, S. Babinec, S. Litzelman, A. Newman, “Status and challenges in enabling the lithium metal electrode for high-energy and low-cost rechargeable batteries,” Nature Energy, pp 16-21, 2018

[5]

A.G.A.M.S. Nanda, “Anode-Free Full Cells: A pathway to High-Energy Density Lithium-Metal Batteries,” Advanced Energy Materials, vol. 11, 2021.