bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estereotipos sobre la sexualidad en la adultez mayor: un análisis desde la perspectiva de género
Authors: García Villanueva Jorge , Jiménez Delgadillo Gabriela de Jesús , Hernández Ramírez Claudia Ivonne 
Published: November 2020

El objetivo de la investigación consistió en analizar los estereotipos en torno a la sexualidad en la adultez mayor de un grupo de egresados de la Licenciatura en Psicología Educativa de una universidad pública de la Ciudad de México. Se empleó una metodología cualitativa con un enfoque comprensivo-interpretativo. La técnica de recolección de información fue una entrevista semiestructurada y el instrumento una guía de entrevista; las preguntas estuvieron enfocadas en la sexualidad, los estereotipos, las percepciones sociales y las características de la adultez mayor. En el estudio participaron siete personas tres hombres y cuatro mujeres, con un rango de edad entre 22 y 35 años. Los hallazgos revelan que la sexualidad continúa siendo un tema tabú, y en la vejez se piensa que no existe manifestación alguna de índole sexual, porque es indecente y de mal gusto. Sin embargo, la propuesta está en comprender que la sexualidad no es única y homogénea, sino que es influenciada por distintos factores, los cuales condicionan las múltiples representaciones que circundan en el imaginario colectivo y conforman subjetividades particulares.
Filo yönetimi için büyük veri temelli yeni sürücü davranış modelleri
Authors: TERZİ Ramazan , SAĞIROĞLU Şeref , ÇÖÇÜ Özge , ARKAN Rabia , TOSUN Merve , TULGAR Yusuf 
Published: November 2020

Bu çalışmada, filo yönetim
sistemlerinin eksikleri hem büyük veri hem de sürücü davranışı bakış açılarıyla
incelenmiş, gerçek veriler üzerinde sürücü/sürüş davranışları analiz edilmiş
bunun sonucunda veri analizlerini gerçekleştirmek için büyük veri tabanlı yeni
modeller önerilmiştir. Büyük veri üzerinde 6 farklı senaryo ile filodaki
sürücülerin davranış farklılıkları, çeşitli lokasyonlardaki davranışları ve
spesifik noktalardaki davranışları büyük veri temelli yaklaşımlar ile tespit
edilmiş yeni modeller geliştirilmiştir. Elde edilen sonuçlardan, özellikle %50 üzerinde hız limiti aşan
sürücüler arasında belirli sürücülerin diğer sürücülere göre %30 oranında bu
ihlallerde payı olduğu, ortalama hızları aynı olsa bile hız ihlalleri bakımından
sürücüler arasında 6 kat farklılık olabileceği, benzer şekilde hız ihlal
sayıları aynı olsa bile ihlal sürelerinde 2 kata yakın fark olabileceği, mevsimlere
göre hız ihlal sayısının en fazla yaz mevsiminde fakat ihlal süresinin en fazla
sonbaharda olduğu, Ankara ili içinde hız limitlerini aşmaya olanak sağlayan
yolların ilçe bazında %23,6 oranıyla Yenimahalle, mahalle bazında %4,62 oranı
ile Saray, şehirlerarası yol bazında %6,85 oranı ile Eskişehir yolunun, şehir
içi yollarda ise %2,74 oranı ise Anadolu Bulvarı olduğu, son olarak ise radar
noktaların yaklaşık 1 kilometre öncesi ve sonrası hız ihlal sayılarına göre 3
farklı radar noktası incelemesinde %300’e yakın oranlarda farklılıkların
oluştuğu tespit edilmiştir. Sonuç olarak büyük veri analitiği kullanarak
filoların sürücü/sürüş davranış kapsamında daha etkili kullanılabileceği ve
daha kolay yönetilebileceği, gerek maliyet gerekse iş gücü kaybının önlenmesi
için bu modellerden faydalanılabileceği, Ankara ili için yapılan bu analizlerin
diğer iller için de kullanılabileceği, radar noktalarında yapılan analizler
gibi farklı değerler üretilebileceği değerlendirilmektedir.
Ankara Celal Bayar Bulvarı’nın karayolu gürültüsü açısından eski ve yeni düzenlemesinin karşılaştırılması
Authors: ÖZÇETİN Zuhal , DEMİREL Füsun 
Published: November 2020

Gürültü, insan sağlığını fizyolojik ve psikolojik olarak etkilediği gibi, iş ve eğitim yaşamında da performansı olumsuz etkilemektedir. Gürültünün insan sağlığı üzerindeki etkisinin 55–60 dB düzeyinde oluşmaya başladığı ve 65 dB düzeyinden sonra sağlık sorunları ve davranış bozuklukları meydana getirdiği bilinmektedir. Gürültü problemi tüm Dünya’da mevzuat kapsamına alınarak, önemli denetimler getirilmiştir. Bu kapsamda çalışmada; Ankara’nın en işlek caddelerinden biri olan Celal Bayar Bulvarı’nın alan ölçümleri aracılığı ile eski ve yeni düzenlemesi arasındaki fark ortaya konularak, trafik gürültüsünün analizi yapılmıştır. Seçilen örnek çalışma alanında; 2016 yılına kadar alt geçit olmadan kullanım mevcut olup, 2017 yılında trafik, alt geçit aracılığı ile düzenlenmiştir. Araştırmada; her iki zaman periyodunun belirli aralıklarında, mevzuatlara uygun olarak çevresel gürültü ölçümleri (Lgündüz, Lakşam, Lgece) yapılarak, araç sayımları gerçekleştirilmiş ve elde edilen veriler ile hesaplamaları (Lgag) yapılmıştır. Bu bağlamda, karayolunun alt geçit uygulama öncesi (Mayıs 2016) ve sonrası (Mayıs 2017) mevcut durumu, çevresel gürültü ölçümleri bağlamında değerlendirilerek, analiz edilmiştir.
Celal Bayar Bulvarı üzerindeki mevcut durum değerlendirmesi ile iki noktada (9. ve 10. noktalar) yapılan ölçüm analizleri ışığında; karayolu çevresel gürültü düzeyinin, alt geçit çalışması öncesinde elde edilen sonuçlara göre; azaldığı görülmekle birlikte, her iki zaman diliminde de (2016 ve 2017) gürültü düzeyinin sınır değerlerin üzerinde olduğu tespit edilmiş ve bu bağlamda öneriler geliştirilmiştir.
An Industrial Perspective on Robot Learning
Authors: Wahrburg Arne , Listmann Kim , Enayati Nima , Kirsten René 
Published: November 2020

Das Thema „Robot Learning“ erfährt in der akademischen Welt zurzeit große Aufmerksamkeit, insbesondere die Anwendungvon Reinforcement Learning in der Robotik. Aus industrieller Sicht versprechen die rasanten Fortschritte im Bereich Robot Learning verkürzte Inbetriebnahmezeiten, vereinfachte Programmierung, höhere Produktivität und Kostenreduktionen. In diesem Beitragwird das Potenzial der Technologie hinsichtlich industrieller Anwendungen beleuchtet. Es werden wesentliche Herausforderungen herausgestellt und mögliche Ansätze diskutiert, wie Ergebnisse aus dem Bereich Robot Learning in Richtung industrieller Anwendbarkeit getrieben werden können.
Eine Online-Plattform für Digitale Zwillinge
Authors: Scheifele Christian , Verl Alexander , Tekouo William , Belgharda Samir , Mauderer Timo 
Published: November 2020

Zunehmend suchen Komponentenhersteller nach Lösungen zur Bereitstellung von digitalen Abbildern ihrer realen Komponenten. Ziel ist es, dass Kunden damit ihre Automatisierungskonzepte virtuell validieren und Steuerungssysteme im Entwicklungsprozess anhand einer virtuellen Inbetriebnahme eingehend testen und optimieren können. Simulationswerkzeuge für die virtuelleInbetriebnahme bieten mittlerweile vielfältige Schnittstellen zur Einbindung bestehender Teilmodelle bei der Modellierung eines digitalen Zwillings einer Maschine oder Anlage. In diesem Beitrag wird die Online-Plattform „TwinStore“ für den Austausch von Simulationsmodellen zur virtuellen Inbetriebnahme vorgestellt.
ASPECTOS RELACIONADOS À INTERNAÇÃO HOSPITALAR EM ADULTOS PORTADORES DE HIV/AIDS
Authors: Silva Cícera Eugenia Pereira , Dolce de Lemos Ligia Mara , Silva Juliana Oliveira Musse , Lima Lidiane de Souza , Teles Maria Josiene Menezes , Guimarães Maria Alzira D’ávila Nery 
Published: November 2020

Resumo
Objetivo: analisar aspectos relacionados à internação hospitalar em portadores de HIV/aids. Método: trata-se de um estudo transversal, realizado no Hospital Universitário de Aracaju/SE, no setor de infectologia. Resultados: a amostra foi composta por 40 adultos HIV reagentes. Dos 40 participantes, 24 (60,0%) eram homens, 20 (50,0%) possuíam faixa etária abaixo de 40 anos e 27(67,5%) com menos de oito anos de estudo. Quanto à internação hospitalar 31 (77,5%) apresentaram diagnóstico tardio do HIV, com doenças relacionadas à aids, a exemplo de pneumonia 2 (5,0%) e tuberculose 4 (10,0%). Conclusão: os dados deste estudo permitem afirmar que homens, população jovem e com pouca escolaridade são aspectos que corroboram para a internação hospitalar. A predominância entre os pacientes que apresentaram diagnóstico tardio é preocupante, principalmente por revelar falhas nos processos do cuidado à saúde.
Palavras- chave: HIV; Aids; Hospitalização; Terapia Antirretroviral de Alta Atividade.
A Didactic Engineering in the Research Process of the Generalization of the Padovan Sequence: An Experience in a Pre-Service Teacher Training Course
Authors: Machado Vieira Renata Passos , Alves Francisco Regis Vieira , Catarino Paula Maria Machado Cruz 
Published: November 2020

Background: Obstacles are found during the epistemological construction of mathematical concepts research, aiming to contribute to the Didactics of Mathematics through a study of Padovan sequence. Objectives: describe elements of a systematic study, based on Didactic Engineering in conjunction with the Theory of Didactic Situations. I addition, referring to the generalization model of Padovan sequence and promoting a historical-evolutionary understanding and its mathematical properties. Design: it presents the most representative data of an investigation supported by the foundations of Didactic Engineering research design, in association with the Theory of Didactic Situations teaching methodology. Setting and Participants: the research was developed in 2019 and applied in a Pre-Service Mathematics Teacher Training Course in the History of Mathematics discipline, with the eight students enrolled. Data collection and analysis: data validation occurred internally due to the short period of the research. Results: it describes an investigation around the object of study, the Padovan sequence, focusing on the generalization process of this sequence and its properties. Thus, three problem situations are elaborated and analyzed based on the assumed research and teaching methodologies, seeking to examine their properties and the student's intuitive thinking, before the insertion of a historical-epistemological conception of this investigation. Conclusions: the research makes it possible to extract repercussions, suggest and promote research scripts aiming at the formation of teachers (initial) in the context of the teaching of History of Mathematics.
Efficacy and safety of cisplatin and paclitaxel (PlaTax regimen) in the neoadjuvant treatment of patients with stage II–III triple-negative breast cancer
Authors: Gordeeva O. O. , Kolyadina I. V. , Zhukova L. G. , Ganshina I. P. , Vyshinskaya G. V. , Kazantseva M. A. , Sukhova M. V. , Ryabishina O. E. , Lubennikova E. V. , Filonenko D. A. , Chichikov E. I. , Polushkina I. N. , Borisova E. I. , Lud A. N. , Meshcheryakov A. A. 
Published: November 2020

Background. Treatment results for the patients with stage II–III triple negative breast cancer (TN BC) have to be improved. Not only the new treatment regimens, but new predictive and prognostic factors should to be developed.Materials and methods. We included 98 patients with stage II–III TN BC in our study. We studied efficacy and safety of PlaTax regimen (cisplatin 75 mg / m2 day 1 + paclitaxel 80 mg / m2 days 1, 8, 15, course every 4 weeks) in this cohort of patients. We assessed pathologic response, survival and factors, which were relevant for predicting response and prognose survival.Results. PlaTax regimen is characterized by high efficacy and tolerable toxicity. Clinical efficacy was 85.8 %, pCR achievement was 60.5 %, tpCR achievement was 58.1 %. The regimen has low haematological toxicity (neutropenia III–IV grades – 4.1 %); the most frequent adverse events were polyneuropathy (18.5 %) and decreased renal function (24.5 %). 3-year progression-free survival was 68.4 %, most of the relapses (92 %) occurred during first 2 years. 3 year overall survival was 77.6 %. The most relevant predictive factor was level of Ki-67 ≥50 % (pCR 38.5 % vs. 68.7 %, p = 0.038). pCR achievement was the most important prognostic factor, resulting in improved 3-year progressionfree survival (44.3 % vs. 89.1 %, p <0.0001), and 3-year overall survival (61.5 % vs. 91.6 %, p = 0.001). Not only the residual disease, but also the size of residual tumor was important from prognostic point of view. Other important prognostic factors were size of the tumor, status of regional lymph nodes, grade. Delay in surgical treatment more than a month lead to decreased 3-year progression-free survival: 87.1 % vs. 62.5 % (p = 0.047).Conclusions. Our data suggest that studied regimen could be an option for patients with stage II–III TN BC. The assessment of the predictive and prognostic factors will help improve the treatment results for patients with stage II–III TN BC.
Parathyroid carcinoma. The experience of treatment of 15 patients and a review
Authors: Severskaya N. V. , Ilyin A. A. , Chebotareva I. V. , Zhelonkina N. V. , Polkin V. V. , Isaev P. A. , Derbugov D. N. , Podvyaznikov S. O. 
Published: November 2020

Background. Parathyroid cancer (PC) is extremely rare, usually diagnosed after surgery, there are no clinical recommendations for the treatment of metastatic PC.The study objective is to present the results of a clinical examination and treatment of patients with PC.Materials and methods. Retrospective analysis of 15 PC patients treated from 2001 to 2019. The results of laboratory tests, the surgical approach, the results of treatment, the rate of metastasis and relapse within 19 months (3 months – 11.6 years) after surgery are presented.Results. Tumor size is 35 mm (20–45 mm). Lymph node metastases – 1 (6.7 %), distant metastases – 2 (13 %). The median initial parathyroid hormone (PTH) is 735 pg/mL, calcium 3.22 mmol/L. Severe hyperparathyroidism with osteitis fibrosa cystica – in 6 (40 %). The surgical approach was parathyroidectomy in 10 (67 %), en bloc resection in 5 (33 %). Normalization of PTH and calcium after surgery – 13 (87 %). In two patients with distant metastases, the PTH and calcium remained high. A patient with Th6 vertebral metastasis was successfully operated on, with normalization of PTH and calcium, and 1.5 years was without relapse. A patient with lung and liver metastases received sorafenib after surgery, with decrease in calcium level. She died of progression 12 months after operation. Among patients with normalization of postoperative PTH, one had local relapse after 4 years. The patient was re-operated and 1 year after the second operation without relapse. The remaining patients are without relapse/progression.Conclusion. At the time of diagnosis, lymph node metastases are in 6.7 %, distant metastases – 13 %. Normalization of PTH and calcium after surgery suggests a good prognosis, but does not exclude the recurrence in the future, which requires long-term follow-up. Repeated surgery for local recurrence or solitary distant metastases can provide stable remission. Sorafenib in metastatic PC has managed to control hypercalcemia in the short term, however, antitumor efficacy requires further study.
Does morphology have real impact on local and distant recurrences in head and neck cutaneous melanoma?
Authors: Mudunov A. M. , Pak M. B. , Demidov L. V. , Baryshnikov K. A. 
Published: November 2020

Introduction. The term “local recurrence” is usually understood as regrowth of a tumor after surgical treatment. The regrowth appears within 3–5 cm from postoperative cicatrix. The causes for such prolonged tumor growth or recurrence of patients with cutaneous melanoma are nonradical surgical treatment as well as satellite or transit metastases that were not removed in-block with primary tumor. A great number of clinical researches, aimed at examination of melanoma, its patterns, anatomical criteria and features of clinical course, gave an opportunity to separate satellite or transit metastases into an independent group. Such metastases are realized inside or subdermally, up to 2 cm or more than 2 cm from the primary tumor, yet, not reaching the location of the first regional barrier.The aim of the study is to define influence of the main prognostic factors such as tumor thickness according to Breslow, the level of invasion according to Clark and the presence of ulceration on the frequency of local recurrence with cutaneous melanoma of head and neck.Materials and methods. The research involved 174 patients with cutaneous melanoma of head and neck (1995–2014). According to our index of contraction of a skin flap (median 30 %) the true borders of resection were clearly defined within all the patients. Thereby, 3 groups were identified with the following resection margin: 1.0 cm, where followed-up treatment results were analyzed.Results. Progression-free survival didn’t correlate with the size of surgical resection margins. The survival rates were the best with the lowest resection margin under 0.5 cm (77.3 %) and the worst with the highest resection margin more then 1.0 cm (38.7 %). That means that the treatment results don’t depend on the width increase of tumor resection margin.Conclusions. We consider that clear surgical margins for any thickness of cutaneous melanoma of head and neck should be as follows: 4 mm – 0.72 mm (p = 0.016). In our work, the influence of the main prognostic factors, such as tumor thickness according to Breslow, level of invasion according to Clark and ulceration on the frequency of head and neck cutaneous melanoma local recurrences had no impact.
Survival of patients with salivary gland malignancies depending on the molecular profile of the tumor
Authors: Kutukova S. I. , Imyanitov E. N. , Raskin G. A. , Ivaskova Yu. V. , Belyak N. P. , Yaremenko A. I. , Razumova A. Ya. , Baykalova P. M. 
Published: November 2020

Introduction. Standard methods of drug or radiation therapy administration for salivary gland cancer is the least successful for now. Therefore, the identification of new markers with morphological features is extremely necessary to improve the effectiveness of treatment and increase the survival rates of patients with this pathology.The study objective is to assess the prevalence of expression of HER2/neu, PD-L1, and RET mRNA in salivary gland malignancies and assess their impact on overall and disease-free survival.Materials and methods. Fifty-nine patients with a confirmed diagnosis of salivary gland cancer (stages II–IVA) were examined in the period from 2012 to 2014 at Saint Petersburg City Clinical Oncology Dispensary. All materials were subjected to immunohistochemical research to determine the expression of HER2, PD-L1 in tumor and immune cells, the CPS index was calculated, and the frequency of the mRNA gene RET expression using a real-time polymerase chain reaction was detected.Results. The overall survival of patients with mild and high HER2 expression was 41 months (95 % confidence interval (CI) 4.50–72.00), which is more than 4 time less than in patients with low or no expression (p = 0.00715). Significant differences were also received in the progression-free survival in the group of patients with negative or insignificant expression of HER2 receptors. The overall survival of patients with CPS >1 was 72 months (95 % CI 19.5–72.00) and significantly differed from the group of patients with CPS <1, where it was not yet achieved (p = 0.0124). mRNA expression of the RET gene was detected in 13 out of 48 cases, which was 27.08 %. The expression level ranged from 0 to 0.205. The progression-free survival in the group of patients with mRNA expression was 168 months (95 % CI 16.00–168.00) and tended to increase in the group of patients who did not have this expression.Conclusion. When analyzing the obtained data, it was proved that knowledge of the salivary glands malignant tumors receptor status become one of the factors in determining the prognosis of the disease, as well as a predictive factor of targeted drugs effectiveness (after сonducting prospective randomized studies).
Holocaust Denial: Social Conditionality and Comparative Analysis of Criminal Law Prohibition
Authors: Vetoshkina E. D. 
Published: November 2020

From the second half of the 20th century the revisionist movement has spread among scientists, public and political figures. Publicists and scientists are known for criticizing the testimonies of concentration camp prisoners and their executioners, as well as denying the possibility of mass extermination of prisoners in terms of the technical capabilities of gas chambers.Attempts to reinterpret historical events often border on extremism and pose a threat to national security, leading to a significant deterioration in international relations. At the international level, a number of acts have been adopted indicating that the Holocaust is a fact established by the verdict of the Nuremberg Tribunal, and calling on states to reject any denial of the Holocaust. International organizations that oppose attempts to rewrite history include the Council of Europe, the United Nations, and UNESCO.At the national level, responsibility for denying and justifying the Holocaust has been established in a number of states. The first group includes states that are responsible for denying and approving the Holocaust and other crimes committed by the Nazis (Germany, France, Austria, Israel). The second group includes states that equated Nazi crimes in their legislation with crimes of communism (Hungary, Czech Republic, Lithuania). The third group consists of states that prohibit the denial and justification of any genocide (Switzerland, Luxembourg). Some states (for example, the United States) refused to introduce such bans, citing freedom of speech and belief.In 2014, the Criminal Code of the Russian Federation introduced article 354.1 "Rehabilitation of Nazism", which sets forth responsibility for denying the facts established by the Nuremberg Tribunal verdict. At the same time, the legislator should not selectively approach the protection of historical events. It would be fair to criminalize the denial of genocide and other international crimes recognized by the international community, regardless of any criteria relating to the perpetrators.
PSHA Compatible Probabilistic Seismic Site Response Analysis for Oslo, Norway
Authors: Carlton Brian , Kaynia Amir M. 
Published: November 2020

ABSTRACTThis article describes a probabilistic site-response analysis for the city of Oslo, Norway. We first perform a probabilistic seismic hazard analysis (PSHA) for hard rock. Then, we conduct site-response analyses using Monte Carlo simulations to capture uncertainty in the site profile. We include four base-case soil profiles to incorporate epistemic uncertainty, and we vary the shear-wave velocity profile and shear-modulus reduction and damping curves to account for aleatory variability. We base the soil profiles on over 7000 in situ tests, and the shear-wave velocity profile median, standard deviation, and interlayer correlation on over 559 cone penetration tests. Next, we perform regression analyses to estimate medians and standard deviations of site-specific amplification factors (AFs). Finally, we modify the ground-motion models for rock with the AFs and recompute the PSHA for the soil surface. The analyses show that (1) shallower soil profiles have larger uniform hazard spectra (UHS) values at short periods and smaller UHS values at long periods; (2) epistemic uncertainty of the base-case soil shear-wave velocity profile leads to alternative UHS values with a difference of a factor of 2 at short periods; (3) there is only a small difference in the mean magnitudes and distances controlling the hazard for the PSHA conducted for rock compared to soil; (4) response spectra calculated from site-response analyses with no aleatory variability of the soil properties predict significantly smaller spectral acceleration values at periods shorter than the natural site period; (5) using site amplification standard deviations based on ground-motion recordings, instead of site-response analyses, results in a 10%–20% reduction in the soil surface UHS at short periods and a 5%–10% increase at long periods; and (6) the Eurocode 8 AFs are, in general, conservative for Oslo.