bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mental Health of Adolescent Relatives of Intensive Care Patients: Benefits of an Open Visitation Policy
Authors: Fergé Jean-Louis , Banydeen Rishika , Le Terrier Christophe , Fize Hélène , Miguel Mathurina , Kentish-Barnes Nancy , Jehel Louis , Moroy Anne , Valentino Ruddy , Mehdaoui Hossein 
Published: January 2021

Background
Symptoms of anxiety and depression are common in adolescents with a loved one in an intensive care unit (ICU) and are known precursors of posttraumatic stress disorder (PTSD).

Objectives
To assess the prevalence of PTSD and associated factors in adolescent (age 12–17 years) relatives of patients in an ICU with an open visitation policy.

Methods
One year after the patient was discharged from the ICU, eligible adolescent relatives completed a satisfaction survey, anxiety history questionnaire, and psychometric evaluations (Hospital Anxiety and Depression Scale and 8-item Children’s Revised Impact of Event Scale).

Results
Thirty-two patients intubated for &gt;2 days and with a Simplified Acute Physiology Score II &gt;30 were included. Forty-six adolescents with first- to third-degree relationships to the patient, and in regular contact (≥monthly) with the patient before hospitalization, were enrolled. The prevalence of PTSD among the adolescents was 33%. Adolescents who visited the ICU were less likely to report feelings of regret than those who did not visit the ICU (2% vs 9%, P = .01). A past sense of threat (odds ratio [95% CI], 19.4 [1.9-201.2]; P = .01) and anxiety and depression symptoms (odds ratio [95% CI], 9.6 [1.4-63.7]; P = .02) were independent factors associated with probable PTSD.

Conclusions
A cautiously prepared open visiting policy should be maintained for adolescents with a relative in the ICU, because it could prevent feelings of regret and subsequent PTSD. Adolescents with risk factors should be screened and followed up.
Providing a Model of Agritourism In Rural Development Case study: Masal county, Guilan Province, Iran
Authors: Chenari H. Mahmoudi , Sheikhani Nejad M. A. Rahimipour , Jan Agha F. Nasiri , Jensi Z. , Kahaki F. 
Published: January 2021

Purpose : The main purpose of this study is to present a model of agritourism for rural development. Based on the quantitative approach and principles of sustainable tourism theory, it tries to present the optimal model of agritourism for rural areas of Masal county. An attempt is also made to identify the elements of agritourism and discovere their internal relations in order to evaluate its development. Research Method : This is a descriptive-analytical study with a mixed research method, i.e. a combination of quantitative and qualitative methods. The research tools in this study include several types of questionnaires and interview cards. For the purpose of data analysis, a variety of statistical tests are used in quantitative and qualitative sections. Findings : The results show that the optimal model of agritourism for rural development in Masal county will be possible in each of the three elevated areas in the presence of five factors, namely tourists, farmers, rural environments, facilitators and common agricultural activities in the region. However, in this study the role of the two factors, including facilitators and rural environments in Masal area is far more than the other three factors. It is also found that, depending on the prevailing conditions in the studied rural areas, the foothills, plain and mountain areas are suitable for agritourism activities, respectively. Originality/ Value : For the first time in Iran, this research has addressed the issue of agritourism model. Also, all the elements of agritourism have been studied together for the first time.
Arboreal Tiger Beetles Recorded from Lowland Crop Cultivations in Sri Lanka
Authors: Abeywardhana D. L. , Dangalle C. D. , Mallawarachchi Y. W. 
Published: January 2021

Purpose : Thirty-one species of arboreal tiger beetles are known from Sri Lanka of which 25 species are endemic. However, their habitat types are poorly documented and the available records are far outdated. Therefore, a survey of tiger beetles was carried out to determine their present occurrence with emphasis on agricultural habitat types. Research Method : Forty-six locations of the country, covering eighteen districts, all provinces, representing a majority of bioclimatic zones except those in Montane Sri Lanka were surveyed for arboreal tiger beetles. Sampling was conducted using the visual encounter method. Collected beetles were identified using taxonomic keys and descriptions. Findings : Eight species of arboreal tiger beetles were collected from the survey. Majority of the species (06) were collected from crop cultivations of coconut and also from tea, fruit farms, betel leaf, cinnamon and pepper. Four species of Derocrania and two species of Tricondyla were recorded from the cultivations and all had fused elytra and hence unable to fly. Derocrania scitiscabra was the dominant arboreal tiger beetle species in the crop cultivations. Originality/ Value : The study documents hitherto unrecorded habitat types for a poorly documented important beetle group of Sri Lanka. It further provides information for future research on the possibility of using arboreal tiger beetles as bio-control agents of insect pests of agricultural crops.
DONOR KIR3DL1/RECEPTOR HLA-BW4-80I COMBINATION REDUCES ACUTE LEUKEMIA RELAPSE AFTER UMBILICAL CORD BLOOD TRANSPLANTATION WITHOUT IN VITRO T-CELL DEPLETION
Authors: Fang Xinchen , Zhu Xiaoyu , Tang Baolin , Song Kaidi , Song Kaidi , Yao Wen , Wan Xiang , Liu Huilan , Sun Zimin , Peng Jun 
Published: January 2021

Background: Donor natural killer (NK) cell alloreactivity in umbilical cord bone marrow transplantation (UCBT) can lead to leukemic relapse. However, NK cell function is calibrated by interaction with human leukocyte antigens (HLAs). This study aimed to investigate graft-resistant leukemia after transplantation and compared specific genotypes of killer immunoglobulin-like receptors (KIRs) in donors and human leukocyte antigen ligands in patients.
Methods: We retrospectively analyzed 232 patients with acute leukemia from a single center. Patients had undergone UCBT with myeloablative conditioning and without anti-thymocyte globulin. We identified the KIR genotypes of cord blood donors using polymerase chain reaction with sequence-specific primers. All of the donors contained KIR3DL1.
Results: The patients were divided into three groups according to the HLA-B locus. The donor KIR3DL1 and recipient HLA-Bw4-80I combination was predictive of being highly educated, and was associated with a lower relapse (P = 0.006) and better overall survival (probability of relapse = 0.13, P < 0.001) than the uneducated group. We found no significant increase in the incidence of acute or chronic graft-versus-host disease.
Conclusions: Our data suggest that the donor KIR3DL1/receptor and HLA-Bw4-80I combination in UCBT results in stronger graft-versus-leukemia effects and improved outcomes in patients with acute leukemia.
INFLUENCE OF NUTRITION ON DISEASE SEVERITY AND HEALTH-RELATED QUALITY OF LIFE IN ADULTS WITH SICKLE CELL DISEASE
Authors: Kamal Sanaa , Naghib Moheyeldeen Mohamed , Al Zahrani Jamaan , Hassan Huda , Moawado Karim  Abdel Aziz , Arrahman Omar 
Published: January 2021

Background & Aims: Sickle cell disease (SCD has a worldwide distribution and causes significant morbidity and mortality in children and adults. Few studies addressed the determinants of SCD severity in adults; therefore, we investigated the impact of nutrition on the outcome of SCD and health-related quality of life (HRQoL) in adult patients,
Methods: In this longitudinal study, we recruited and prospectively followed 62 adults with SCD (aged ?18 years) for a median of 93 months. At entry and follow-up, patients provided medical and dietary history, had a physical examination and anthropometric measurements, assessment of protein-energy intake, measurement of micronutrient levels, estimation of SCD severity score, and determination of the HRQoL (SF-26v2). The study outcome was a composite of hospitalization due to SCD crises or death.
Results: At baseline, 42 (67.74%) patients had macro and, or micro-undernutrition (Group A), and 20 (32.26%) were well nourished. (Group B). The BMI and most anthropometric measurements were significantly lower in SCD patients compared to control subjects. In several SCD patients, undernutrition resulted from reduced food intake and reduced absorption due to concomitant gastrointestinal disorders. Seventy percent of SCD patients had vitamin D, vitamin B12, and zinc deficiencies. Under-nourished patients had significantly higher SCD severity scores, frequent SCD related hospitalizations, higher mortality rates, and reduced HRQoL compared to well-nourished patients. Protein-energy and micronutrient deficiencies were independent predictors of severe SCD and mortality. Correction of undernutrition and hydroxyurea therapy improved SCD severity scores and HRQoL.
Conclusion: Patients with sickle cell disease have various degrees of macro and micro deficiencies, which increase SCD severity and hospitalizations and reduce the health-related quality of life. Early diagnosis and prompt correction of macro and micronutrient deficiencies need to be incorporated in the standard of care of SCD patients to improve the disease outcomes.
Clinical and laboratory features of Hemoglobin La Desirade variant in association with sickle cell and alpha thalassemia genes
Authors: Alkindi Salam , Al Zadjali Shoaib , Al Rawahi Mohamed , Al Haddabi Hamoud , Daar Shahina , Elsadek Refaat Abdullah , Sherkawy Bahaa Eldeen Diab , Pathare Anil 
Published: January 2021

Abstract
Hemoglobin La Desirade (Hb La Desirade) is an unstable hemoglobin variant characterized by amino acid Alanine (Ala) replacing Valine (Val) at position 129 (H7) in the beta chain. Hb La Desirade exhibits a decreased oxygen affinity and normal heme-heme interaction. Interestingly, on analysis by standard electrophoresis, it migrates in the same region as normal HbA, and HbA actually represents a combination of HbA and Hb La Desirade together. This variant was reported as compound heterozygous with other Hemoglobin variants such as HbS, HbC or beta thalassemia, and more recently with Southeast Asian ovalocytosis and Hb Louisville with varying clinical manifestations. Herein, we describe the clinical and laboratory findings in a number of Omani Arab families who presented to our service for various reasons, presenting with Hemoglobin La Desirade with sickle gene and alpha thalassemia. Our patients with Hb La Desirade trait, were clinically asymptomatic with no evidence of anemia. However when it is associated with other abnormal hemoglobin variants such as HbS, leading to sickle/La Desirade compound heterozygosity, there was mild anemia with significant degree of hypochromia and microcytosis. The most striking feature was that the levels of HbS and HbA were almost equal on HPLC, and these cases could be misdiagnosed as sickle cell trait (SCT). However, the levels of Hb S in these compound heterozygotes (40.4-45.9) were higher than normally seen for the diagnosis of SCT in this population.
Brain and Acute Leukemia, Cytoplasmic Gene Overexpression as a Prognostic Factor in Egyptian De novo Adult Acute Myeloid Leukemia Patients
Authors: Alnagar Ahmed A , Hagrassy Hesham M Al , Abdullah Rania M , Shabrawy Reham M El , Salah Hossam 
Published: December 2020

Abstract
Background: Brain and acute leukemia, cytoplasmic (BAALC) gene is identified on chromosome 8q22.3 and implicated in normal hematopoiesis. BAALC gene overexpression is associated with poor outcome. Methods: We aimed to evaluate BAALC expression in de novo Egyptian acute myeloid leukemia (AML) cases and determine its prognostic value. We recruited 70 patients with de novo AML diagnosed and treated at clinical pathology and medical oncology departments, fulfilling inclusion criteria in our prospective study and evaluated BAALC expression level. Patients received induction therapy. The Institutional Review Board approved our study. Results: The mean age was 39.2 years ± 11.87, (18–60) with a male/female ratio of 3/2. The cutoff value of BAALC as a prognostic factor was 2.11 with sensitivity (86.1%), specificity (80%), positive predictive value (88.6%), and negative predictive value (76.2%.) (P < 0.001), 43 (61.4%) patients had high BAALC expression. Seventy-two percent of patients in the low BAALC group achieved complete remission (CR) compared to 42.1% in high BAALC expression group (P = 0.03). Patients with low BAALC (123.1 ± 4.9) had longer mean survival time than high BAALC group (45.85 ± 5.1) (P = 0.000). Conclusion: High-BAALC expression is an adverse prognostic factor, with a higher risk of relapse, lower CR rates, and lower survival in Egyptian de novo AML patients.
Caracterização florística e fitossociologia de um fragmento de Cerradão em Cáceres, Mato Grosso
Authors: Verly Otávio Miranda , Oliveira Iuri Maicon Moreira de , Santos Cristman Taísse Félix dos , Fialho Junior Leonardo Leite , Rosa Poliane Rodrigues , Chaves Arthur Guilherme Schirmbeck , Franco Fernanda Miguel 
Published: December 2020

A fragmentação de habitats causa diversos impactos ecossistêmicos. A resposta da vegetação às mudanças ambientais a tornam um bom indicador do estado de conservação da biodiversidade. O objetivo deste trabalho foi avaliar a conservação de um fragmento de Cerradão no município de Cáceres, MT, pela análise da estrutura horizontal e da diversidade de espécies do estrato arbóreo-arbustivo. O levantamento foi baseado em dois conglomerados aleatorizados, totalizando 8 parcelas em 0,8 ha. O critério de inclusão foi o diâmetro a 1,30 m do solo ≥ 10 cm. Foram amostrados 411 indivíduos, 44 espécies e 21 famílias botânicas. As famílias Fabaceae e Bignoniaceae apresentaram as maiores riquezas. Os valores dos índices de diversidade de Shannon-Weaver e de equabilidade de Pielou foram considerados elevados (3,18 e 0,84, respectivamente). A similaridade florística entre os conglomerados foi alta (índice de Sørensen = 74,63%), indicando homogeneidade no fragmento. A distribuição diamétrica apresentou o padrão J-invertido. A comunidade apresentou tendência ao agregamento, com índice de agregação de Payandeh médio (1,40). A riqueza e estrutura da vegetação indicaram bom estado de conservação do estrato arbóreo-arbustivo, pois não foram observadas alterações florístico-estruturais no fragmento oriundas das pressões antrópicas do entorno da área.
AFGHAN STUDENTS’ PURPOSES OF USING FACEBOOK AT MIRWAIS KHAN NIKA ZABUL INSTITUTE OF HIGHER EDUCATION, ZABUL, AFGHANISTAN
Authors: Himat Abdul Nafi , Nazari Habib Rahman 
Published: January 2021

The aim of this study is to investigate the students’ purposes of using Facebook at Mirwais Khan Nika Zabul Institute of Higher Education, Qalat, Zabul province, Afghanistan. In this research, the quantitative research method was employed, and the data was collected from 115 students through a designed questionnaire. In addition, the respondents were selected through random sample. Additionally, the data was analyzed by implementing IBM 24 version of Statistical Package for the Social Sciences (SPSS), and found out the frequency and percentage of the items as well reported in a table. Moreover, the findings of this research reveal that learners use Facebook for several goals such as for socializing in order to be socialized in a society, getting social information, read news and for educational purposes, but they did not practice Facebook for the aims to pass their time, and share photos with their friends on the Facebook.
JEL Classification Codes: A19, B10, B25, C10, C53
MODELO DE GESTIÓN SOSTENIBLE PARA EL PLANETARIO DE LA ARMADA DEL ECUADOR
Authors: Aguila Gabriela , Carpio Freire Carlos Raul 
Published: January 2021

El presente estudio de investigación de tipo exploratorio y descriptivo, tuvo como objetivo elaborar un modelo de gestión que permita la sostenibilidad del Planetario de la Armada del Ecuador. Para su desarrollo fue preciso realizar una evaluación de la infraestructura actual y los servicios que ofrece a la ciudadanía con el fin de encontrar indicadores idóneos que sirvan de guía para la estructuración de un plan que este orientado hacia la mejora continua y que sirva de apoyo al momento de diseñar e implementar una estrategia de intervención sostenible. Además, se realizó un análisis comparativo del Planetario de la Armada del Ecuador con el Observatorio de Astronómico ubicado en la ciudad Quito, Ecuador; el Planetario Galileo Galilei, ubicado en la ciudad de Buenos Aires, Argentina; y, el Hayden Planetarium, situado en la ciudad de New York, Estados Unidos. El análisis comparativo fue basado en el Modelo de Benchmarking adaptado por Robert de Camp (Del Giogio Solfa , 2012). Con los resultados de este estudio, se pretende mejorar la percepción y opinión ciudadana respecto al Planetario de la Armada del Ecuador, que debido a la serie de debilidades que presenta, ha impedido que se mantenga más posicionado en la mente de la comunidad, y se muestre como un punto de interés turístico para locales y extranjeros que visitan la ciudad de Guayaquil en forma constante.
EL ARTE DE LOS ANDES
Authors: Rojas Kelly 
Published: January 2021

El caso muestra la historia del Ugo de Censi y la obra que realizó a partir de su llegada a Chacas, poblado localizado en el centro de los Andes, región Ancash (Perú). Esta zona, aparte de estar alejada de la capital del Perú, ha sido un lugar con bajos recursos durante muchos años, antes de la llegada de este poblador. Asimismo, a través del caso se conocerá a Perú, uno de los países en América Latina con economía emergente, basada principalmente en sus factores productivos tradicionales. Durante la estancia de Ugo en Chacas, que iba a ser su retiro como sacerdote y párroco, acaecieron varios sucesos. Él reconoció que este lugar tenía grandes carencias, de todo tipo, por lo que decidió hacer algo, olvidarse de tener una vida más placentera y ayudar a estos pobladores a través de la Operación Mato Grosso (OMG), a través de voluntarios. Dicha operación permitió que varios voluntarios apoyaran obras que él iba realizando en este lugar (y otras, en un futuro). Gracias a la toma de sus decisiones, sus gestiones y la ayuda de otras personas (voluntarios de la OMG), superó las condiciones de vida de los pobladores, que el Estado no podía cubrir, en cuanto a: salud, educación y formación en valores, acceso a servicios de agua y luz, la posibilidad de tener un oficio que genere valor agregado.
La labor de los voluntarios, que no necesariamente tenían que ser creyentes sino solo tener deseos de ayudar, consistía en realizar diferentes labores, por ejemplo: tirar la lampa, ayudar a embalsar un río, vacunar a niños, levantar casas, diseñar muebles, vitrales, estatuas, mosaicos, tejidos, dar de comer, cocinar (para cerca de 700 personas diariamente y que tenían que distribuir gratuitamente), enseñar y formar a técnicos, artesanos, maestros, agricultores, entre otros. Todo esto lo realizaban los voluntarios de forma gratuita, sin recibir pago alguno, por un periodo de tres a seis meses; quienes obtenían una experiencia muy enriquecedora y agradable. Lo que Ugo realizó en este lugar consistió en una transformación completa. Una economía con nulas capacidades de desarrollo, como Chacas, se convirtió en un centro de operaciones con apertura y calidad de exportación mundial. Donde no había educación de calidad, él la colocó. Donde no había un nivel de producción de alto nivel, sino solo el desarrollo de fuente de producción agrícola, él lo transformó en fuente de desarrollo social, comercial y cultural. Es decir, cambió la economía tradicional por una economía emergente, que aún sigue viva.
Determinan Pemilihan Implan Pada Pasangan Usia Subur Di Kecamatan Medan Petisah
Authors: Rahmi Ayu Amalia , Hadi Ella Nurlaella 
Published: January 2021

ABSTRAKLatar belakang. Penduduk Indonesia mengalami peningkatan dari 265.015.300 orang pada tahun 2018 menjadi 268.074.600 orang pada tahun 2019. Pemerintah membuat program untuk mengintervensi masalah pertumbuhan penduduk yang tidak terkendali yaitu program keluarga berencana (KB). Metode Kontrasepsi Jangka Panjang (MKJP) dengan implan menjadi salah satu alat kontrasepsi unggulan dari BKKBN.Tujuan. Penelitian ini bertujuan untuk melihat gambaran perilaku pemilihan implan dan determinannya.Metode. Penelitian ini menggunakan metode kuantitatif dengan survei analitik cross sectional. Sampel 85 akseptor dari 560 dipilih dengan menggunakan simple random sampling. Pengumpulan data dilakukan melalui wawancara dengan menggunakan kuesioner. Data dianalisis secara univariat dan bivariat menggunakan uji chi-square.Hasil. Sebanyak 11.8% responden menggunakan metode implan. 71.8% responden memiliki pengetahuan kurang, 65.9% responden bersikap negatif, 83.5% responden menilai peran petugas kesehatan masih kurang dan 67.1% responden yang tidak mendapatkan dukungan suami. Hasil analisis bivariat menunjukkan bahwa terdapat hubungan antara pengetahuan, peran petugas kesehatan, dan dukungan suami dengan pemilihan kontrasepsi implan, sedangkan sikap menunjukkan tidak ada hubungan dengan pemilihan konstrasepsi implan.Kesimpulan. Ada hubungan antara variabel pengetahuan, peran tenaga kesehatan, dan dukungan suami dengan pemilihan Implan pada responden. ABSTRACTBackground. Indonesia's population has increased from 265,015.3 million in 2018 to 268,074.6 million in 2019. The government has created a program to intervene in the problem of uncontrolled population growth, namely the family planning (KB) program which is promoted and effective is the Long-Term Contraception Method (MKJP) with implants is one of the superior contraceptives of the BKKBN. Objective. This study aimed to to see the selection of implants and their determinations. Method. This study used a quantitative study with cross sectional analytic survey method. Sample of 85 acceptors from 560 were selected using simple random sampling. Data collection was carried out through interviews using a questionnaire. Data were analyzed by univariate and bivariate using chi-square test. Results. Study found 11.8% of respondents used the implant method. 71.8% respondents have less knowledge, 65.9% of respondents have a negative attitude, 83.5% of respondents think that the role of health workers is still lacking, and 67.1% of respondents did not get support from their husbands. The results of the bivariate analysis showed that there was a relationship between knowledge, the role of health workers, and husband's support with the choice of implant contraception, while attitudes showed no relationship with the choice of implant contraception.Conclusion. Knowledge variables, the role of health workers, and husband's support was related with the choice of implants in respondents.
CRIAÇÃO DE UM CENTRO TECNOLÓGICO DE HABITAÇÃO, URBANISMO E MEIO AMBIENTE E O FORTALECIMENTO DO PODER NACIONAL
Authors: Cavalheiro Ronaldo Goytacaz 
Published: December 2020

Ao construir sua primeira casa, o Homem deu início uma extraordinária aventura que, no Brasil, evoluiu do conceito da Casa-grande ao dos Prédios Inteligentes, os quais convivem com a triste realidade das habitações de favelas e do próprio déficit habitacional dos dias atuais.
A expansão das cidades exige o Planejamento Urbano, hoje respaldado na Constituição de 1988, e tendo ferramentais de alta tecnologia a seu dispor como, por exemplo, as imagens de satélites e os computadores.
A preocupação com o meio ambiente obriga a que repensemos tanto as nossas megalópoles como a ocupação da Amazônia, a fim de que possamos nos desenvolver e preservar.
Sendo o desenvolvimento científico tecnológico e a busca de melhor qualidade de vida duas das principais metas do Homem no final do Século XX, por que não colocar a tecnologia a serviço da qualidade de vida?
A melhor forma que a humanidade tem utilizado para solucionar seus grandes problemas com auxílio de alta tecnologia é a criação de centros tecnológicos.
Um Centro Tecnológico da Habitação, Urbanismo e Meio Ambiente poderá gerar soluções satisfatórias para os problemas de ocupação dos espaços brasileiros.