bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep-water depositional architecture and sedimentary evolution in the Rakhine Basin, northeast Bay of Bengal
Authors: Ma Hong-Xia , Fan Guo-Zhang , Shao Da-Li , Ding Liang-Bo , Sun Hui , Zhang Ying , Zhang Yong-Gang , Cronin Bryan T. 
Published: April 2020

AbstractSince the consecutive discovery of several gas fields from 2004 to present, the Rakhine Basin has been an active area for petroleum exploration in the Bay of Bengal. High-resolution 3D seismic data and well data from blocks AD1, AD6 and AD8 offshore northwest Myanmar are used to study the Miocene–Pleistocene depositional architecture and sedimentary evolution in the Rakhine Basin. Analysis of seismic facies and seismic attributes indicates that deep-water architectural elements include submarine canyons, confined slope channel complex systems, aggradational channel–levee complexes, isolated channels, frontal splays and mass-transport complexes, which have variable characters (shape, dimension, sedimentary architecture) within predominantly background deep-water slope-basin floor facies. Most of the sediments are interpreted to be sourced from the Ganges–Brahmaputra fluvio-deltaic system to the north with only minor lateral input from the Indo-Myanmar Ranges to the east. Investigation of the depositional evolution and architectural elements transformation during the filling history of the Rakhine Basin suggests the Rakhine Basin experienced rapid progradation during the Oligocene–Middle/Upper Miocene, gradual retrogradation during the Middle/Upper Miocene–Early Pliocene and gradual progradation during the Early Pliocene–Pleistocene. Published exploration results indicate that the main reservoirs of the discoveries in blocks A1 and A3 are Pliocene frontal splays and channel–levee fills, dominated by fine and very fine-grained sandstones, in structural and structural–stratigraphic traps. Analytic results from seismic characters and several exploration wells indicate that channel complexes and associated overbanks and frontal splays with fine-grained sandstones and siltstones trapped by the four-way closures are primary reservoir targets.
Particle velocity measurement of binary mixtures in the riser of a circulating fluidized bed by the combined use of electrostatic sensing and high-speed imaging
Authors: Zhang Wen-Biao , Wang Tian-Yu , Liu Yao-Yao , Zhan Wen-Bo , Wang Chi-Hwa 
Published: April 2020

AbstractThe flow dynamics of binary particle mixtures in the fluidized bed needs to be monitored in order to optimize the related industrial processes. In this paper, electrostatic sensing and high-speed imaging are applied to measure the velocities of polyethylene and sand particles in the binary particle mixtures in fluidization. Experimental studies were conducted on a lab-scale cold circulating fluidized bed. Correlation function between electrostatic signals from upstream and downstream electrodes placed along the riser shows two peaks that represent transit times for the two types of particles. To verify the above results, high-speed imaging was adopted to capture the flow images of particle mixtures. Particle Image Velocimetry and Particle Tracking Velocimetry algorithms were utilized to process the resulted images in order to measure the velocities of polyethylene and sand particles. The reasons for two-peak correlation functions are illustrated based on the frequency spectrums of the mono-solid-phase electrostatic signals and the velocity difference between polyethylene and sand particles. Finally, comparisons on the velocities obtained from electrostatic sensing and high-speed imaging demonstrate the electrostatic sensor can roughly estimate the particle velocity of binary particle mixtures in the near wall region of the circulating fluidized bed.
Prognostic Nutritional Index as a Predictor of Postoperative Outcome in Patients Aged 85 Years or Older After Colorectal Cancer Surgery
Authors: Tsuruta Atsushi , Watanabe Yusaku , Mineta Shumei , Tanioka Hiroaki , Nagasaka Takeshi , Fujiwara Yoshinori , Ueno Tomio 
Published: April 2020

AbstractThe preoperative prognostic nutritional index (PNI) calculated based on the serum albumin concentration and peripheral blood lymphocyte count has been reported to correlate with the prognosis in patients undergoing cancer surgery. However, in case of very old patients over 85 years old, the value of preoperative PNI in colorectal cancer has not been studied in any detail. The aim of this study was to assess the PNI as a predictor of postoperative outcome in elderly patients over 85 years old with colorectal cancer. We performed a retrospective review in forty-five patients over 85 years old who underwent colorectal tumor resection at our hospital from April 2013 to March 2018. The correlations between preoperative PNI and postoperative complications were examined. The incidence rate of postoperative complications was 31.1% (14/45). All of cases with postoperative complications were improved conservatively. The median preoperative PNI was 43.20 (range 24.05–57.05) in the validation study. According to the receiver operating characteristic (ROC) curve, cutoff value of PNI was set at 45.0 in the validation study. An univariate analysis demonstrated that PNI (p = 0.0006), operation style (elective/emergency) (p = 0.03), operation approach (open/laparoscopy) (p = 0.03), and T factor (p = 0.04). A multivariate analysis showed that PNI was independent predictive factor of postoperative complications. Moreover 3-year overall survival rates of patients in the PNI ≧ 45 and PNI < 45 were 100% and 63.8%, respectively (p = 0.009). This study suggested that PNI is a pivotal independent predictor of the postoperative outcome among elderly patients over 85 years old after colorectal cancer surgery.
Biosorption of Cr(III) and Cr(VI) species on NaOH-modified peel of Artocarpus nobilis fruit. 1. Investigation of kinetics
Authors: Samaraweera A. P. G. M. V. , Priyantha N. , Gunathilake W. S. S. , Kotabewatta P. A. , Kulasooriya T. P. K. 
Published: April 2020

AbstractPerformance characteristics of peel of Artocarpus nobilis fruit can be enhanced by the treatment of the biosorbent with aqueous NaOH solutions under stirred conditions, followed by thorough washing of the treated biosorbent with water. A series of experiments performed within a wide range of solution pH demonstrates that the optimum pH for Cr(III) removal is pH 5.0, while it is 2.0 for Cr(VI) by peel of Artocarpus nobilis fruit after treatment with aqueous NaOH solutions of concentrations varied from 0.0050 to 0.15 M. Adsorption of Cr(III) and Cr(VI) from individual aqueous solutions on the above biosorbent treated with 0.010 M NaOH solution, which provides the highest extent of removal of 4.89 × 103 mg kg−1 (pH = 5) and 4.94 × 103 mg kg−1 (pH = 2), respectively, follows pseudo-first-order kinetics at the ambient temperature of 27.5 °C when the concentration of adsorbate concentration is kept relatively constant. The order of the reaction is unchanged when the solution temperature is increased up to 40.0 °C for Cr(III) although the reaction becomes pseudo-second order for Cr(VI). Further, the energy of activation for adsorption of Cr(III) is determined to be 66.82 kJ mol−1, suggesting a strong attraction between the adsorbate and the biosorbent. Application of the intraparticle diffusion model to kinetics data within the early stages of the adsorption process of Cr(III) suggests that boundary layer-retarded diffusion be valid at both solution temperatures, while no retardation be possible for Cr(VI) at the warmer temperature.
Real-World Outcomes Among Patients with Cystic Fibrosis Treated with Ivacaftor: 2012–2016 Experience
Authors: Higgins Mark , Volkova Nataliya , Moy Kristin , Marshall Bruce C. , Bilton Diana 
Published: April 2020

Abstract
Introduction
In this long-term, postapproval, observational study, data from the US Cystic Fibrosis Foundation Patient Registry and the UK Cystic Fibrosis Registry were used to evaluate the impact of ivacaftor treatment on cystic fibrosis (CF) by comparing outcomes in ivacaftor-treated patients with those in matched untreated comparator patients. Registry data from up to 5 years of ivacaftor availability in the US and up to 4 years of availability in the UK were evaluated.

Methods
Starting in the first year of ivacaftor availability, ivacaftor-treated patients in each registry were matched 1:5 to comparator patients who never received ivacaftor. Clinical endpoints were evaluated in annual cross-sectional safety analyses. The key endpoints were death, organ transplants, pulmonary exacerbation, and hospitalization. Relative risks and 95% CIs were calculated to compare the ivacaftor and comparator cohorts in each registry.

Results
Here, we report the complete and final results of the annual cross-sectional safety analyses across the duration of the study, with up to 5 years of follow-up. Data show a pattern of lower risk of death, transplant, pulmonary exacerbation, and hospitalization among ivacaftor-treated patients in both registries.

Conclusions
Ivacaftor-treated patients had consistently favorable clinical outcomes relative to untreated comparators, and no new safety concerns were identified. While general limitations of observational research apply, these findings support disease modification by CF transmembrane conductance regulator (CFTR) modulator therapy with ivacaftor. Future research of novel CFTR modulators will need to explore alternative methods for comparator selection for evaluation of clinical data given the evolving landscape of CF treatment.
A hybrid power system based on fuel cell, photovoltaic source and supercapacitor
Authors: Ferahtia Seydali , Djerioui Ali , Zeghlache Samir , Houari Azeddine 
Published: April 2020

AbstractIn this study, we present an ameliorated power management method for dc microgrid. The importance of exploiting renewable energy has long been a controversial topic, and due to the advantages of DC over the AC type, a typical DC islanded micro-grid has been proposed in this paper. This typical microgrid is composed of two sources: fuel cell (FC), solar cell (PV) and one storage element [supercapacitor (SC)]. Here, we aimed to provide a management strategy that guarantees optimized bus voltage with arranged power-sharing between the sources. This proposed management aims to provide high-quality energy to the load under different loading conditions with variable solar irradiance, taking into account the FC state. Due to the slow dynamics of the FC, the SC was equipped to supply the transient period. A management algorithm is implemented to hold the DC bus voltage stable against the load variations. The management controller is based on differential flatness approach to generate the references. The DC bus is regulated by the SC energy; to reduce the fluctuations in the DC bus voltage, The PI controller is implemented. This proposed strategy reduces the voltage ripple in the DC bus. Moreover, it provides permanent supplying to the load with smooth behaviour over the sudden changes in the demand as depicted in the simulation results. Our study revealed that this proposed manager can be used for this kind of grids easily.
Real time in‐vivo miniature endoscopic surveillance system for imaging of nasopharynx
Authors: Lim Chwee Ming , Rao Gangodu Nagaraja , Ren Hongliang 
Published: April 2020

ObjectiveTo test the feasibility of a real time miniature endoscope system for imaging the nasopharynx.Study designPreclinical assessment on skull model and cadaver.MethodsA 3.5 mm miniature endoscope was fabricated and the image capture of the nasopharynx was investigated by positioning the miniature camera system at the posterior free edge of the vomer bone. Wireless real time transmission of the images and quality was tested in a skull model. Next, three nasopharyngeal surveillance miniature camera system were developed for possible clinical translation. Two prototypes were anchored on the nasal septum and the last prototype was designed using a patient self‐administered surveillance process. These prototypes were tested for feasibility on both the phantom skull and cadaveric model. Risk assessments were also performed to assess risk, safety and validate the reliability of the material utilized for clinical translation.ResultsInsertion and anchorage of the miniature surveillance endoscope prototypes at the vomer bone were feasible on all 3 prototypes. The quality of captured images was reasonable and miniaturized camera was responsive to pan at different angles so that the entire nasopharynx may be surveyed. Risk assessments on the material such as pull out test, breaking force analysis, finite element test and tensile strength test were reliable for possible clinical translation.ConclusionsReal time miniature endoscope system for surveillance of nasopharyngeal cancer is feasible. Clinical translation of this technology was possible but requires further refinement in enhancing image quality and wireless transmission of the captured images.
The Dark Side of Cultural Intelligence: Exploring Its Impact on Opportunism, Ethical Relativism, and Customer Relationship Performance
Authors: Lorenz Melanie P. , Ramsey Jase R. , Andzulis James “Mick” , Franke George R. 
Published: April 2020

ABSTRACTEmployees who possess cross-cultural capabilities are increasingly sought after due to unparalleled numbers of cross-cultural interactions. Previous research has primarily focused on the bright side of these capabilities, including important individual and work outcomes. In contrast, the purpose of this study is to demonstrate that the cross-cultural capability of cultural intelligence (CQ) can lead to both positive and negative outcomes. Applying the general theory of confluence, we propose that expatriates high in CQ excel in customer relationship performance, while simultaneously behaving opportunistically. We also suggest that ethical relativism moderates these relationships. Using mixed methods, four separate studies generally support our predictions while also deepening our understanding of various forms of opportunism and the mechanism behind two seemingly opposing effects. Conceptual and managerial implications of CQ for opportunism, customer relationship performance, and ethics are discussed.
Paleomagnetic observations from lake sediments on Samosir Island, Toba caldera, Indonesia, and its late Pleistocene resurgence
Authors: Solada Katharine E. , Reilly Brendan T. , Stoner Joseph S. , de Silva Shanaka L. , Mucek Adonara E. , Hatfield Robert G. , Pratomo Indyo , Jamil Rendi , Setianto Baskoro 
Published: April 2020

AbstractApproximately 74 ka, Toba caldera in Sumatra, Indonesia, erupted in one of the most catastrophic supereruptions in Earth's history. Resurgent uplift of the caldera floor raised Samosir Island 700 m above Lake Toba, exposing valuable lake sediments. To constrain sediment chronology, we collected 173 discrete paleomagnetic 8 cm3 cubes and 15 radiocarbon samples from six sections across the island. Bulk organic 14C ages provide an initial chronostratigraphic framework ranging from ~12 to 46 ka. Natural and laboratory magnetizations were studied using alternating field demagnetization. A generally well-defined primary magnetization is isolated using principal component analysis. Comparison of inclination, and to a lesser degree declination, across independently dated sections suggests paleomagnetic secular variation (PSV) is recorded. Average inclination of −6° is more negative than a geocentric axial dipole would predict, but consistent with an eastward extension of the negative inclination anomaly observed in the western equatorial Pacific. The 14C- and PSV-derived age model constrains resurgent uplift, confirming faster uplift rates to the east and slower rates to the west, while suggesting that fault blocks moved differentially from each other within a generally trapdoor-type configuration.
From six to zero per cent Mycobacterium avium subsp. paratuberculosis milk ELISA positivity in three years – probably induced by Mycobacterium vaccae
Authors: Elad Daniel , Lysnyansky Inna , Falk Rama , Blum Shlomo E. , Weisbelith Limor , Mikula Inna , Shwimmer Adin 
Published: April 2020

AbstractThis research communication reports the results of a study aimed at investigating the effects of introducing Mycobacterium vaccae on paratuberculosis carriage in a dairy herd. M. vaccae is a non-pathogenic member of the Mycobacteriaceae, with immunomodulatory and immunotherapeutic capabilities, acting by stimulating the cellular immune system, important in protection against paratuberculosis. Starting in 2014 we administered, by gavage, 1010 live M. vaccae bacteria to all new-born heifers on a dairy farm, first within 24 h of birth and again 2 weeks later. Paratuberculosis carriage was monitored yearly by milk ELISA. Faecal samples of 50% of cows, aged 3 years, born 1, 2 or 3 years before the experiment's onset, were tested by qPCR for MAP shedding and compared to 100% treated cows of the same age. Within 3 years, milk ELISA positivity was reduced from 6 to 0% and remained unchanged for the subsequent 2 years. One qPCR positive control cow was found each year for a total of 3 animals (2.46%). One positive cow (1%) was found among the treated cows. Two of the 3 positive control animals, still present on the farm at the end of 2019, tested negative whereas the positive test cow continued shedding MAP. M. vaccae shedding heifers mixing with adult cows were the probable means of the microorganism's propagation. The results of this investigation indicate that the introduction of live M. vaccae may be an inexpensive and fast alternative to current paratuberculosis control practices, justifying further exploration of the topic.
It is a family affair: individual experiences and sibling exposure to emotional, physical and sexual abuse and the impact on adult depressive symptoms
Authors: Kullberg Marie-Louise , van Schie Charlotte , van Sprang Eleonore , Maciejewski Dominique , Hartman Catharina A. , van Hemert Bert , Penninx Brenda W. J. H. , Elzinga Bernet M. 
Published: April 2020

AbstractBackgroundChildhood abuse and neglect often occurs within families and can have a large influence on mental well-being across the lifespan. However, the sibling concordance of emotional abuse and neglect (i.e. together referred to as emotional maltreatment; EM), physical abuse (PA) and sexual abuse (SA) and the long-term impact on the context of siblings' maltreatment experiences are unclear. To examine the influence of EM, PA and SA on adult depressive symptoms within the family framework we differentiate between (a) the family-wide (mean level of all siblings) effects and (b) the individual deviation from the mean family level of maltreatment.MethodsThe sample (N = 636) consists of 256 families, including at least one lifetime depressed or anxious individual and their siblings. Multilevel modeling was used to examine the family-wide and relative individual effects of childhood maltreatment (CM).Results(a) Siblings showed most similarity in their reports of EM followed by PA. SA was mostly reported by one person within a family. In line with these observations, the mean family levels of EM and PA, but not SA, were associated with more depressive symptoms. In addition, (b) depression levels were more elevated in individuals reporting more EM than the family mean.ConclusionsParticularly in the case of more visible forms of CM, siblings' experiences of EM and PA are associated with the elevated levels of adult depressive symptoms. Findings implicate that in addition to individual maltreatment experiences, the context of siblings' experiences is another crucial risk factor for an individuals' adult depressive symptomatology.
Platelet 3H-imipramine binding in major depressive episodes
Authors: Faludi G , Tekes K 
Published: April 2020

SummaryDensity (Bmax) and affinity constant (Kd) values of tritiated imipramine binding sites were determined on platelets from patients suffering from major depression and from healthy, age-and sex-matched controls. Significantly lower Bmax values were found in the depressed patients, while the Kd values did not differ from those of controls. The results suggest that, in accordance with data from the literature, decrease in 3H-imipramine binding sites may be used as a state-dependent biological marker of depression in clinical practice.
Circadian variations in response to protirelin test in major depressive episode
Authors: Duval F , Mokrani MC , Crocq MA , Rosenberg S , Castro J Oliveira , Valdivieso S , Macher JP 
Published: April 2020

SummaryWe studied circadian thyrotropin (TSH) and prolactin (PRL) response to synthetic thyrotropin-releasing-hormone (protirelin) infusion (200μg IV) at 8 am and 11 pm in 35 drug-free inpatients with DSM III-R Major Depressive Episode and in 22 hospitalized controls. In each group, maximum TSH and PRL responses were lower at 8 am than at 11 pm. The difference between 11 pm-ΔTSH and 8 am-ΔJTSH (ΔΔTSH) was significantly lower in depressed patients compared to controls. No such blunting was observed in PRL responses to protirelin in depressed patients. In the overall population, TSH response to protirelin (ie8 am-ΔTSH, 11 pm-ΔTSH,ΔΔTSH) correlated significantly with TSH circadian parameters (iemesor and amplitude). These correlations were also observed with PRL (except forΔΔPRL). TSH mesor and amplitude were lower in depressives than in controls. In contrast, PRL mesor and amplitude were not significantly different between diagnostic groups.ΔΔTSH is thus a chronobiological refinement to the measure of thyroid axis dysfunction in major depression. The blunted TSH response to protirelin suggests that the TRH receptors of the pituitary thyrotrophs are hyposensitive in major depression.
Antagonism by modafinil of the psychomotor and cognitive impairment induced by sleep-deprivation in 12 healthy volunteers
Authors: Bensimon G , Benoit D , Lacomblez L , Weiller E , Warot D , Weil JS , Puech AJ 
Published: April 2020

SummaryModafinil is a new psychotropic compound with central α1, adrenergic-stimulant activity in animals. In the present study, its pharmacological activity in man was evaluated in the sleep-deprivation induced psychomotor and cognitive impairment paradigm. This was a double-blind placebo-controlled study involving 12 healthy volunteers. Standard psychomotor and memory tasks were used, including critical flicker fusion frequency determination (CFF), choice reaction time and short- and long-term memory evaluation. Results revealed a clear antagonism by modafinil of the psychomotor and cognitive impairment induced by sleep-deprivation in most tasks 6 h after drug administration, and marginal effects 18 h after. These results therefore support a psychostimulant activity of modafinil in man.
Atypical depression: diagnosis and therapeutic issues
Authors: de la Fuente JR 
Published: April 2020

SummaryA number of Meso-American artifacts which appear to depict subjects presenting severe depressive episodes have been identified, showing that concern with depressive disorders is not a recent phenomenon. Atypical presentations of depression in modern Mexico are characterized by a high degree of somatization, perhaps to avoid the stigma of “mental disorders”. Other characteristics are mood reactivity, substantial anxiety, phobias and the reversed vegetative manifestations. There is a high comorbidity with panic disorder and with bipolar depression. Nosological terminology is not fully standardized, and commonly encountered diagnoses include “neurasthenia”, “neurotic depression”, “mixed depression”, “resistant depression”, etc. Treatment involves a variety of modalities, including TCAs, MAOIs, and anxiolytics, together with a number of drug combinations; open trials are underway with newer agents such as SAMe, SSRIs and the RIMAs.