bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic markers derived from 18F-FDG PET/CT in suspected recurrent ovarian carcinoma: predictive value for disease burden and prognosis
Authors: Jain Bela , Khandelwal Yogita , Ora Manish , Mishra Prabhakar , Lal Punita , Gambhir Sanjay 
Published: December 2024

Objective
This study aims to assess the role of 18F-fluorodeoxyglucose (FDG) PET/computed tomography (CT) in suspected recurrent ovarian carcinoma. Several clinical and PET parameters were assessed to evaluate disease burden and prognosis.

Methods
We did a single-center, retrospective study in patients with suspected recurrent ovarian carcinoma who underwent 18F-FDG PET/CT. The disease burden on the scan was evaluated. We calculated several semiquantitative markers, including standard uptake values (SUV), metabolic tumor volume (MTV), and total lesion glycolysis (TLG). Survival analysis was done with clinical parameters, CA-125 levels, disease distribution, and metabolic markers.

Results
Fifty-two patients were included in the study. Half of the patients had suspected recurrence within 12 months of primary diagnosis. PET/CT scan suggested disease in 35 (67.3%) patients. Multiple metastatic sites were noted in 21 (40.4%) patients. Extra-abdominal metastases were seen in 15 (28.8%) patients. Eight patients had 18F-FDG avid disease despite a low CA-125 level (<35 IU). Young patients (<50 years), extra-abdominal disease, multiple metastases, and higher restaging were associated with poor outcomes. Meanwhile, treatment history, CA-125 level, and post-PET/CT treatment had no significant effect on survival. MTV@40% SUV (>17.21) and TLG@40% SUV (>68.7) had the sensitivity of 87.5% and 75% for predicting disease outcome.

Conclusion
Recurrent ovarian carcinoma commonly presents with multiple metastasis and extra-abdominal metastases. 18F-FDG PET/CT-guided patterns of disease distribution were significant markers for poor prognosis. Disease burden on PET/CT-derived semiquantitative parameters was associated with poor outcomes.
Development of organ transplantation in China and organ donation
Authors: Wang Shaofa , Chen Xiaoping 
Published: December 2024

Abstract
This article provides a concise overview of the development of organ transplantation in China. Inspired by international advancements in organ transplantation, China embarked on its own organ transplantation research journey in 1958. The clinical evaluation phase is marked by the first cadaveric kidney transplant in 1960 and the first living-donor kidney transplant in 1972. By 1989, the annual number of successful kidney transplants had surpassed 1000. However, 57 liver transplants were performed between 1977 and 1983; limitations in technology and the scarcity of cyclosporine A resulted in unfavorable outcomes for most recipients, with the majority succumbing within 3 months of surgery. These factors led to a near-complete halt in liver, heart, and lung transplants for the following decade. With all 4 conditions met—(1) mature surgical techniques, (2) powerful immunosuppressive agents available for clinical use, (3) new organ preservation solutions that ensure the quality and transportation of donor organs, and (4) reasonable and legal sources of organs—China's organ transplantation field has experienced rapid development. In 2014, there were 9652 organ transplants, and this number grew to 20,225 by 2022. Despite the progress, China's organ donation rate per million remains relatively low, 3.86 ranking 48th globally in 2022, underscoring the need for increased public awareness and support for organ donation.
Transformation of lung adenocarcinoma into small cell lung cancer after treatment with epidermal growth factor receptor tyrosine kinase inhibitors
Authors: Kuang Linwu , Li Yangkai 
Published: December 2024

Abstract
Epidermal growth factor receptor tyrosine kinase inhibitors effectively improve the prognosis of patients with epidermal growth factor receptor–mutant lung adenocarcinoma. However, acquired resistance inevitably develops with small cell lung cancer transformation emerging as a rare but increasingly frequent mechanism of tyrosine kinase inhibitor resistance. This transformation poses significant challenges to the health of patients with lung cancer and complicates their clinical management. This article comprehensively reviews the diagnostic, predictive, mechanistic, and therapeutic aspects of small cell lung cancer transformation to enhance our understanding and clinical awareness of this phenomenon.
Are Mucinous Carcinomas of the Breast Hard on Elastography?
Authors: Singla Veenu , Gulati Malvika , Singh Tulika , Bal Amanjit , Khare Siddhant 
Published: December 2024

Abstract
Mucinous carcinomas are a rare type of invasive breast carcinoma characterized by large quantities of extracellular mucin on histopathological examination. These tumors can be easily missed or misdiagnosed. Due to large quantities of mucin, these tumors are presumed to be “soft” masses. This pilot study aims to evaluate the strain and shear wave elastography features of these tumors. Out of 485 referred patients with breast cancer between November 2022 and January 2023, 8 cases were diagnosed as mucinous carcinoma breast on histopathology. These were evaluated with strain and shear wave ultrasound elastography in addition to mammography and B-mode ultrasound. Tsukuba elasticity score, fat-to-lesion ratio (FLR), and distance ratios were calculated on strain elastography. Mean elasticity values as well as elasticity ratio were evaluated on shear wave elastography. On mammography, 3/8 masses were equal density, 2/8 were low density, 2/8 were high density, and 1/8 showed extensive calcifications. Microlobulated margins were seen in 6/8 masses, and the rest (2/8) showed circumscribed margins. On ultrasound, 4 masses appeared isoechoic, and the remaining 4 were hypoechoic. On strain elastography, 7/8 (87.5%) masses had Tsukuba elasticity scores of 4 and above; 6/8 had FLR >4.8 and 6/8 had distance ratios >1. The mean elasticity value on shear wave was 149.12 kPa, and the shear wave elasticity ratio was 8.9. Interestingly, despite the presence of large quantities of extracellular mucin in these tumors, mucinous tumors have elastography findings similar to solid malignant breast masses. Hence, elastography is a useful tool in detecting these often-benign-looking masses.
VULVOVAGINAL CANDIDIASIS: KNOWLEDGE, PRACTICES AND OCCURRENCE AMONG PREGNANT WOMEN RECEIVING ANTENATAL CARE IN A TEACHING HOSPITAL, GHANA
Authors: Edziah Florence Shine , Acheampong Princess Ruhama , Tawiah Philip Apraku , Amengor Cedric Dzidzor , Kpene Godsway Edem , Amponsah Grace Otobea , Baffoe Priscilla Appiah , Korankye Georgina 
Published: December 2024

AbstractBackgroundVulvovaginal Candidiasis is a condition commonly caused byCandida albicans. It is the second most common infection of the female genitalia affecting many women worldwide. Studies have identified unhealthy genital care practices associated with the infection among women including expectant mothers. Knowledge of the various signs and symptoms is crucial for early detection, reporting, and treatment. Good knowledge may influence healthy practices limiting the infection and its complications. This study assessed the relationship between knowledge, practices and occurrence of Vulvovaginal candidiasis among pregnant women accessing antenatal care at a teaching hospital in Ghana.MethodsA cross-sectional study was conducted among 336 pregnant women receiving antenatal care at the Ho Teaching Hospital. A structured questionnaire was employed in assessing their knowledge on the infection and some practices regarding vaginal hygiene. Hospital records of these participants were further checked to verify the occurrence of the infection among them. Analysis to identify associations between outcome variables and risk factors as well as significance level was carried out.ResultsOut of the 336 gestational mothers involved in the study, 27% were found to have been diagnosed with candidiasis at the time of the study. Pregnant women who usually use antibiotics had 2.25 increased odds of developing Vulvovaginal Candidiasis (VVC) compared to those who do not [OR:2.25 95CI:1.33-3.79; p-value = 0.003]. Again, a greater percentage of the study participants, 85% had good knowledge whiles 5% had poor knowledge.ConclusionThe occurrence of VVC was elevated in the study jurisdiction. Frequent antibiotic use was found as a significant factor associated with the occurrence of the infection.
Can the co-creation of local food products be a key factor in rural development?
Authors: Fandos-Herrera Carmina , Mercadé-Melé Pere , Rubio Pastor María Ángeles 
Published: December 2024

PurposeThis study aims to comprehensively explore the behaviour of potential consumers in terms of their perception of how local agri-food co-creation activities in rural areas influence the perceived quality of agri-food products and the perceived value of the sustainable development goals (SDGs) in rural areas. To do so, it is important to start by answering the research question: Are consumers interested in the co-creation of agri-food products in rural areas?Design/methodology/approachThe methodology consists of two phases, one qualitative and one quantitative. The first phase includes four interviews with experts on gastronomy, rural tourism and services in rural areas and two focus groups with consumers involved in the research topic. In the quantitative phase, a representative sample of almost 700 people in Spain was obtained.FindingsThe first result shows a high level of interest in participating in co-creation activities with agri-food products in rural areas. Other research results suggest that the social integration of consumers with the local community through co-creation activities could improve the appreciation and market position of local foods, as well as their perceived beneficial effect on sustainable development goals. The results also demonstrate how the perceived value of co-creation activities has a positive impact on the intention to undertake and recommend such activities.Originality/valueThis study highlights the importance of co-creation in rural areas, in line with the SDGs and consumer preferences for locally produced sustainable food. Involving consumers in the production process allows small producers to stand out, fostering innovation and rural development. The results show consumers' interest in co-creation, motivated by altruism and the desire to preserve local heritage. The study highlights the indirect impact of co-creation on rural development, emphasising the perceived value and engagement of consumers. Ultimately, it suggests promoting sustainable rural economies through collaborative efforts between producers, consumers and local stakeholders.
Assessment of barriers to the adoption of innovative building materials (IBM) for sustainable construction in the Nigerian construction industry
Authors: Mogaji Iseoluwa Joanna , Mewomo Modupe Cecilia , Bondinuba Francis Kwesi 
Published: December 2024

PurposeWhile innovative building materials (IBM) have emerged as a promising solution for addressing the global construction industry’s environmental, economic and social challenges, their adoption is plagued with increasing challenges in the Nigerian construction industry (NCI). To provide practical strategies to overcome the present IBM challenges in the NCI, the barriers that hinder its successful adoption need detailed investigation. Consequently, this study examines the barriers that affect the adoption of IBM for sustainable construction (SC) in the NCI.Design/methodology/approachA quantitative research approach was used to obtain primary data from 282 construction professionals, viz. architects, builders, engineers and quantity surveyors, via a closed-ended questionnaire survey. Data were analysed using a mean item score (descriptive analysis) and exploratory factor analysis (inferential analysis).FindingsThe study revealed the top five most significant barriers to IBM adoption in the NCI. These barriers include lack of awareness and knowledge, learning/training period, cost and economic viability, lack of qualified staff and lack of end-user involvement. Factor analysis revealed five components of barriers: resource and policy-related barriers, perception and cultural-related barriers, organisational-related barriers, awareness and market-related barriers and resistance and stakeholder engagement-related barriers.Practical implicationsThe findings of this study have several practical implications for construction professionals, policymakers and other stakeholders in Nigeria. The study highlights the need for increased awareness and technical expertise to promote the adoption of IBM in the NCI. The study also recommends several practical strategies for overcoming the barriers to IBM adoption and promoting SC practices in Nigeria, such as fostering a positive perception of sustainable concepts, fostering stakeholder support and involvement and promoting a more conducive environment for adopting sustainable practices. The implication of this study transcends the local context, offering a model for other countries to consider, thereby contributing to a global shift towards sustainable construction practices.Social implicationsThe findings highlight the critical role of societal attitudes and awareness in adopting IBM, suggesting the need for educational and awareness programmes to shift public and organisational perception. This shows the importance of cultural change and societal readiness to embrace sustainable construction practices.Originality/valueThis study contributes significantly to knowledge of the barriers to adopting IBM for SC in NCI. Findings from the study will inform policymakers, industry professionals and other stakeholders about the key barriers that require attention and intervention, facilitating the initiatives to overcome these barriers effectively.
Posting “what” on social media? The (mis-)use of Facebook by young people in refugee camps
Authors: Baú Valentina 
Published: December 2024

Purpose
This paper aims to shed light on the threats that young people living in refugee camps face in their use of Facebook. While social media enable a participatory process of communication (Russo et al., 2008), which is based on the agency of the communicator and defined by their own cultural and moral goals (Lee et al., 2023), these platforms can at times be inappropriately pursued if the communicator lacks relevant skills. The outcome of such a pursuit can also inadvertently damage social cohesion in the camp and lead to conflict.

Design/methodology/approach
A total of 17 semi-structured interviews were carried out in 2023 with young people between the ages of 20 and 29 living in Kakuma refugee camp. The young refugees were asked questions related to their own behaviour and practices on Facebook and to those of their peers. The focus was specifically on the context of the interactions with other youth in Kakuma and on the camp’s Facebook groups or pages.

Findings
Findings reveal that limited knowledge, understanding and awareness of the functioning and affordances of social media platforms such as Facebook are leading young refugees towards multiple risks involved in public online interactions. This has significant negative impacts not only on the lives of the youth who are active on social media in the camp but also on the relationships with their peers and overall community harmony.

Originality/value
A number of studies have identified some of the dangers arising for refugees operating in online spaces, and particularly on social media platforms (see, for example, Tech Transparency Project, 2022; Dekker et al., 2018). Yet, there is a lack of research on the outcomes that young refugees face in their immediate virtual and physical environment as a result of their online behaviour. To the best of the author’s knowledge, this study is the first to bring to light the nature of the interactions and the dynamics that young, encamped refugees engage in on Facebook and to offer useful reflections that can inform digital literacy efforts carried out by development agencies.
Exploring the significance of knowledge transfer for facilitating cross-border acquisitions: an extensive examination of current themes, gaps, and potential future research directions
Authors: Rani Neelam , Yaqub Muhammad Zafar , Singh Nidhi , Magliocca Pierpaolo 
Published: December 2024

Purpose
The purpose of this paper is to review how knowledge transfer, including knowledge integration, absorptive capacity and reverse knowledge transfer (RKT) in cross-border acquisitions, is examined in existing research work. The authors also propose directions to advance research in cross-border acquisitions.

Design/methodology/approach
A systematic literature review is conducted, and related propositions are advanced based on scientometric and bibliometric analysis of 146 papers published over 10 years about tacit knowledge transfer, innovation activities, industrial policy effect on merger decisions, top management experience and value creation in cross-border acquisition. First, the authors searched major themes with the help of Scopus, and later, the authors analysed all received literature with the help of VOS Viewer.

Findings
This review facilitates us to identify six clusters and main author keywords. These six clusters are the underlying six research streams, including RKT, cultural distances, value creation, absorptive capacity, innovation and reference to India and China.

Originality/value
Despite knowledge transfer constituting important antecedents and critical factors for the success of cross-border acquisitions, knowledge management in the acquired company through proper knowledge transfer and knowledge integration is not given enough attention. Current literature still fails to provide a holistic picture of how firms strategically manage knowledge post-acquisition. To the best of the authors’ knowledge, this study is the first to analyse the dynamics of knowledge transfer in cross-border acquisitions. The study is a novel attempt to relate current research themes to emerging areas of cross-border acquisitions.
Physiological and symbiotic flexibility of reef‐building corals to new habitats: Insights from clonal colony transplants
Authors: Gantt Shelby E. , Keister Elise F. , Jerry Samantha E. , Ferguson Tindal Rose , Manfroy Alicia A. , Merck Dakotah E. , Muller Erinn M. , Kemp Dustin W. 
Published: December 2024

Abstract

Global decline of coral reefs shows varied responses to environmental stress, highlighting the need to understand these differences. The physiological plasticity of coral hosts and their microalgal symbionts can allow the coral holobiont to thrive in diverse marine environments, suggesting new strategies for effective restoration.

To investigate local environmental influence on the physiology of two Caribbean coral species (Acropora palmata and Orbicella faveolata), clonal colonies from a land‐based nursery were transferred to nearshore and offshore reefs for one year.

After transfer to coral reef habitats, both coral species shifted in photopigmentation and host energy reserves. Acropora palmata also shifted dominant symbionts and altered growth.

Stable isotopes identified higher autotrophic proportions of metabolic carbon and higher photosynthesis rates in transplanted colonies compared to those in the land‐based nursery.

Synthesis and applications. These findings improve our understanding of coral acclimatization and physiological plasticity, highlighting potential side effects of domestication. As coral restoration accelerates globally, this knowledge is crucial for guiding efforts and conserving endangered ecosystems by supplying considerations for improving coral‐rearing systems and providing information on genera‐specific acclimatization to transplant sites.
Is gratitude science inclusive? A scoping review on gratitude in individuals with diverse needs and exceptionalities
Authors: Datu Jesus Alfonso D. 
Published: December 2024

AbstractPast meta‐analytic, systematic and narrative reviews have painted a highly optimistic backdrop on the psychological, physical and social rewards associated with gratitude. However, as most of these reviews focused on how gratitude facilitates optimal psychological functioning in typically developing samples, question remains on the extent to which these findings are generalizable to individuals with diverse special needs or disabilities. This scoping review aims to map scholarly evidence on the psychological benefits of gratitude in individuals with various special needs and exceptionalities. Most studies relied on the dispositional gratitude model (~59%) and cross‐sectional designs (~75%) in investigating gratitude in people with diverse needs. Majority of empirical investigations also focused on studying gratitude in Western cultural contexts such as the United States. Further, prior studies showed that gratitude increased positively valenced well‐being outcomes. Future theoretical implications and scholarly directions are charted.
Outcomes of open versus minimally invasive oesophagectomy in an Australian quaternary referral centre: a historical case‐matched study
Authors: Kilpatrick Fiona , Kanhere Harsh , Stranz Conrad , Prasad Shalvin , Sundararajan Krishnaswamy , Edwards Suzanne , Trochsler Markus , Reddi Benjamin 
Published: December 2024

AbstractBackgroundOesophagectomy for surgical management of oesophageal carcinoma has previously been performed via an open approach (OE), with a change in recent years to a minimally invasive technique (MIO). We performed a retrospective study to compare the rates of post‐operative complications between OE and MIO patients at our institution. Secondary outcomes included nodal yield and ICU LOS.MethodsThis is a retrospective, observational, case‐matched single centre study of 2‐stage oesophagectomies for carcinoma from January 2011 to December 2021. Fourty‐four MIO patients were matched by age to 44 OE patients. Post‐operative pulmonary, cardiac and surgical complications were defined using the Esophagectomy Complications Consensus Group (ECCG) guidelines.ResultsBaseline characteristics were similar for the two groups, with a higher ASA grade for patients undergoing MIO. There was no significant difference in post‐operative pulmonary complication rates between the OE versus MIO groups (41% versus 55%, P = 0.29). There were more cardiac arrhythmias in the MIO group however this was not statistically significant (9.1% versus 22.7%, P = 0.08). Rate of re‐operation was equal between the groups with no difference between rates of other surgical complications, ICU LOS or hospital LOS. Significantly higher nodal yield was achieved in the MIO group. Overall rate of Clavien‐Dindo graded complications were similar (55% versus 66%, P = 0.28).ConclusionsMIO was associated with higher lymph node yield, and comparable complication rates when compared to OE and does not significantly alter time spent in hospital.
Failure of formalization: State protection of employer interests and consequences for domestic workers' organizing in India
Authors: Parpiani Maansi 
Published: December 2024

AbstractThis paper examines the demand for, creation and ultimate failure of a legislation aimed at formalizing domestic workers in Mumbai, India. The paper is based on an analysis of parliamentary discussions on the legislation process and ethnographic fieldwork with diverse groups of domestic workers undertaken between 2014 and 2021. I critique the claim that formalization policies are merely ill‐suited to the norms or complexities of domestic work. Instead, I argue that formalization fails because the state drafts laws that actively protect the interest of domestic workers' employers, rather than domestic workers. In drafting a piece of legislation that creates no obligations on employers and offers few immediate benefits to workers, I locate its failure in the context of widespread labor deregulation and a shrinking formal sector in India. Crafting such a law, the state plays a partisan role and stems the momentum of further domestic worker organizing in Mumbai.