bluuebunny/crossref_metadata_2025_split huggingface dataset:
Theoretically predicting the feasibility of highly-fluorinated ethers as promising diluents for non-flammable concentrated electrolytes
Authors: Bouibes Amine , Saha Soumen , Nagaoka Masataka 
Published: December 2020

AbstractThe practical application of nonflammable highly salt-concentrated (HC) electrolyte is strongly desired for safe Li-ion batteries. Not only experimentalists but also theoreticians are extensively focusing on the dilution approach to address the limitations of HC electrolyte such as low ionic conductivity and high viscosity. This study suggests promising highly-fluorinated ethers to dilute the HC electrolyte based on non-flammable trimethyl phosphate (TMP) solvent. According to the quantum mechanical and molecular dynamics calculations, the fluorinated ether diluents showed a miscibility behavior in HC TMP-based electrolyte. While such miscibility behavior of the diluent with TMP solvent has been significantly enhanced by increasing its degree of fluorination, i.e., the “fluorous effect”, it is remarkable that the self-diffusion constant of Li+ and the ionic conductivity should be significantly improved by dilution with bis(1,1,2,2-tetrafluoro ethyl) ether (B2E) and bis(pentafluoro ethyl) ether (BPE) compared to other common hydrofluoroether diluents. In addition, the fluorinated-ether diluents have high ability to form a localized-concentrated electrolyte in HC TMP-based solution, leading to high expectation for the formation of a stable and a compact inorganic SEI film.
Antibiofilm and antivirulence efficacy of myrtenol enhances the antibiotic susceptibility of Acinetobacter baumannii
Authors: Selvaraj Anthonymuthu , Valliammai Alaguvel , Sivasankar Chandran , Suba Manokaran , Sakthivel Ganeshkumar , Pandian Shunmugiah Karutha 
Published: December 2020

AbstractAcinetobacter baumannii (AB) is rising as a human pathogen of critical priority worldwide as it is the leading cause of chronic opportunistic infections in healthcare settings and the condition is ineradicable with antibiotic therapy. AB possesses the ability to form biofilm on abiotic as well as biotic surfaces which plays a major role in its pathogenesis and resistance in clinical settings. Hence, the demand for an alternative therapy to combat the biofilm-associated infections is increasing. The present study explored the antibiofilm potential of myrtenol, a bicyclic monoterpene present in various plants against reference and clinical strains of AB. Myrtenol (200 μg/mL) exhibited a strong antibiofilm activity without exerting any harmful effect on growth and metabolic viability of AB strains. Microscopic analyses confirmed the reduction in the biofilm thickness and surface coverage upon myrtenol treatment. Especially, myrtenol was found to be effective in disrupting the mature biofilms of tested AB strains. Furthermore, myrtenol inhibited the biofilm-associated virulence factors of AB strains such as extracellular polysaccharide, cell surface hydrophobicity, oxidant resistance, swarming and twitching motility. Transcriptional analysis unveiled the suppression of the biofilm-associated genes such as bfmR, csuA/B, bap, ompA, pgaA, pgaC, and katE by myrtenol. Notably, myrtenol improved the susceptibility of AB strains towards conventional antibiotics such as amikacin, ciprofloxacin, gentamicin and trimethoprim. Thus, the present study demonstrates the therapeutic potential of myrtenol against biofilm-associated infections of AB.
The excellent peroxidase-like activity of uniform CuCo2O4 microspheres with oxygen vacancy for fast sensing of hydrogen peroxide and ascorbic acid
Authors: Han Shuai , Chen Xiaohan , Fan Yifei , Zhang Yuexing , Yang Zhongdong , Kong Xia , Liu Zhenxue , Liu Qingyun , Zhang Xianxi 
Published: December 2020

The uniform CuCo2O4 microspheres with oxygen vacancy were firstly found to possess excellent peroxidase-like activity which is essential for constructing a rapid and facile colorimetric sensor to determine H2O2 and interrelated biomolecules.
The influence of various regions of the FOXP2 sequence on its structure and DNA-binding function
Authors: Thulo Monare , Rabie Megan A. , Pahad Naadira , Donald Heather L. , Blane Ashleigh A. , Perumal Cardon M. , Penedo J. Carlos , Fanucchi Sylvia 
Published: December 2020

Abstract
FOX proteins are a superfamily of transcription factors which share a DNA-binding domain referred to as the forkhead domain. Our focus is on the FOXP subfamily members, which are involved in language and cognition amongst other things. The FOXP proteins contain a conserved zinc finger and a leucine zipper motif in addition to the forkhead domain. The remainder of the sequence is predicted to be unstructured and includes an acidic C-terminal tail. In the present study, we aim to investigate how both the structured and unstructured regions of the sequence cooperate so as to enable FOXP proteins to perform their function. We do this by studying the effect of these regions on both oligomerisation and DNA binding. Structurally, the FOXP proteins appear to be comparatively globular with a high proportion of helical structure. The proteins multimerise via the leucine zipper, and the stability of the multimers is controlled by the unstructured interlinking sequence including the acid rich tail. FOXP2 is more compact than FOXP1, has a greater propensity to form higher order oligomers, and binds DNA with stronger affinity. We conclude that while the forkhead domain is necessary for DNA binding, the affinity of the binding event is attributable to the leucine zipper, and the unstructured regions play a significant role in the specificity of binding. The acid rich tail forms specific contacts with the forkhead domain which may influence oligomerisation and DNA binding, and therefore the acid rich tail may play an important regulatory role in FOXP transcription.
Quantifying Post-Swallow Residue in Healthy Aging
Authors: Jardine Marie , Miles Anna , Allen Jacqui , Leonard Rebecca 
Published: December 2020

Purpose
Reports are mixed on whether post-swallow residue increases with age. This question was investigated using a quantitative measure of residue in a large cohort of healthy adults. It was hypothesized that post-swallow residue would differ between younger and older healthy adults, and significantly increase in individuals ≥ 80 years.

Method

In this observational study, 275 healthy volunteers aged 18–99 years underwent videofluoroscopic swallow studies. Post-swallow residue was quantified using the Bolus Clearance Ratio (BCR) for a 20-ml thin liquid barium bolus and 3-cm
3
barium paste bolus. Number of swallows required per bolus and aspiration were also determined as additional markers of swallow efficiency and safety.

Results
Most BCR values were low, < 0.05 (< 5% of the bolus) for 78% of 20 ml and 66% of paste swallows. BCR values were significantly larger in healthy older adults, although, clinically, the differences are arguably minimal (differences in mean BCR values between age groups: 20 ml: 0.01 [1%]; paste: 0.03 [3%]). For 20 ml, 56% of adults ≥ 80 years performed multiple swallows (oral residue and dose metering) versus 9% of adults 18–39 years. One aspiration event was observed.

Conclusions
Post-swallow residue was slightly increased in older adults; many individuals ≥ 80 years performed more than one swallow per bolus to achieve this similar level of clearance. This suggests a reduction in swallow efficiency with age without compromising swallow safety. Post-swallow residue that poses a risk of airway invasion should be considered a sign of swallowing dysfunction, not healthy aging.
Time slot‐split NOMA with resource allocation in full‐duplex cooperative communications
Authors: Wang Xuan , Liu Yi , Ma Ying , Zhang Hailin 
Published: December 2020

AbstractThis paper presents a time slot‐split non‐orthogonal multiple access (TSS‐NOMA) scheme for full‐duplex (FD) cooperative communication systems to improve resource utilisation. Aiming at the problem of low bandwidth efficiency when pairing users, TSS‐NOMA divides a complete time slot into several parts to improve the pairing process. Users can occupy all bandwidths in different slots to reduce the waste of bandwidth resources. Unlike the scheme of forwarding a single signal, TSS‐NOMA decodes the information symbols of relay, and re‐encodes the messages through the new power allocation factors of successfully paired users. The hybrid symbols are sent to increase the proportion of central users' own signals received by themselves, thus improving the ergodic capacity of the system. To maximise the minimum achievable rate of the system, TSS‐NOMA optimises the power allocation at the base station, and the relay. The performance of TSS‐NOMA is verified by simulation, where numerical results show that this scheme can achieve higher spectral, and energy efficiency.
Robust data‐driven fixed‐order controller synthesis: Model matching approach
Authors: Daş Ersin , Başlamışlı Selahattin Ç. 
Published: December 2020

AbstractIn this paper, a new data‐driven fixed‐order controller design method based on convex optimisation is proposed for linear single input single output systems. The proposed non‐parametric frequency domain data based approach renders the need for a mathematical model of the controlled plant unnecessary. First, a semi‐definite convex optimisation algorithm is proposed to simultaneously compute a minimal uncertainty model and an optimal nominal model from the experimental data. Then the robust performance condition, control input constraints and the closed‐loop model matching objective are described by convex functions with respect to the parameters of the controller. The usefulness and efficiency of the proposed approach are verified experimentally with application to the control of a thrust vector control system.
Fully relative state constraint impulsive consensus of nonlinear multi‐agent systems via state‐dependent impulsive protocols
Authors: Zhang Qiangqiang , Li Chuandong , He Zhilong , Han Yiyan 
Published: December 2020

AbstractIn this paper, the state‐dependent impulsive consensus problem of nonlinear multi‐agent systems in directed topology with fully relative state constraint impulses is investigated. State‐dependent impulsive protocols are designed for achieving leader‐following exponential consensus. By constructing comparison systems, consensus problem of multi‐agent systems with state‐dependent impulses can be simplified to the ones with fixed‐time impulses. In addition, state constraint impulses are considered to limit the jump values of impulses beyond the threshold. Based on algebraic graph theory, convex analysis, comparison principle and stability theory, some novel criteria of impulsive consensus have been proposed. Authors' main results indicate that fully relative state constraint impulsive consensus of nonlinear multi‐agent systems via state‐dependent impulsive protocols can be achieved if the nonlinear systems satisfy suitable conditions. Numerical simulations are presented to validate the effectiveness of theoretical results.
Providing clear pruning threshold: A novel CNN pruning method via L0 regularisation
Authors: Li Guo , Xu Gang 
Published: December 2020

AbstractNetwork pruning is a significant way to improve the practicability of convolution neural networks (CNNs) by removing the redundant structure of the network model. However, in most of the existing network pruning methods l1 or l2 regularisation is applied to parameter matrices and the manual selection of pruning threshold is difficult and labor‐intensive. A novel CNNs network pruning method via l0 regularisation is proposed, which adopts l0 regularisation to expand the saliency gap between neurons. A half‐quadratic splitting (HQS) based iterative algorithm is put forward to calculate the approximation solution of l0 regularisation, which makes the joint optimisation problem of regularisation term and training loss function can be solved by various gradient‐based algorithms. Meanwhile, a hyperparameters selection method is designed to make most of the hyperparameters in the algorithm can be determined by examining the pre‐trained model. The results of experiments on MNIST, Fashion‐MNIST and CIFAR100 show that the proposed method can provide a much clearer pruning threshold by widening the saliency gap, and achieve a similar or even better compression performance, compared with the state‐of‐the‐art studies.
The search for radio emission from the exoplanetary systems 55 Cancri,υAndromedae, andτBoötis using LOFAR beam-formed observations
Authors: Turner Jake D. , Zarka Philippe , Grießmeier Jean-Mathias , Lazio Joseph , Cecconi Baptiste , Emilio Enriquez J. , Girard Julien N. , Jayawardhana Ray , Lamy Laurent , Nichols Jonathan D. , de Pater Imke 
Published: December 2020

Context.The detection of radio emissions from exoplanets will open up a vibrant new research field. Observing planetary auroral radio emission is the most promising method to detect exoplanetary magnetic fields, the knowledge of which will provide valuable insights into the planet’s interior structure, atmospheric escape, and habitability.Aims.We present LOFAR (LOw-Frequency ARray) Low Band Antenna (LBA: 10–90 MHz) circularly polarized beamformed observations of the exoplanetary systems 55 Cancri,υAndromedae, andτBoötis. All three systems are predicted to be good candidates to search for exoplanetary radio emission.Methods.We applied theBOREALISpipeline that we have developed to mitigate radio frequency interference and searched for both slowly varying and bursty radio emission. Our pipeline has previously been quantitatively benchmarked on attenuated Jupiter radio emission.Results.We tentatively detect circularly polarized bursty emission from theτBoötis system in the range 14–21 MHz with a flux density of ~890 mJy and with a statistical significance of ~3σ. For this detection, we do not see any signal in the OFF-beams, and we do not find any potential causes which might cause false positives. We also tentatively detect slowly variable circularly polarized emission fromτBoötis in the range 21–30 MHz with a flux density of ~400 mJy and with a statistical significance of >8σ. The slow emission is structured in the time-frequency plane and shows an excess in the ON-beam with respect to the two simultaneous OFF-beams. While the bursty emission seems rather robust, close examination casts some doubts on the reality of the slowly varying signal. We discuss in detail all the arguments for and against an actual detection, and derive methodological tests that will also apply to future searches. Furthermore, a ~2σmarginal signal is found from theυAndromedae system in one observation of bursty emission in the range 14–38 MHz and no signal is detected from the 55 Cancri system, on which we placed a 3σupper limit of 73 mJy for the flux density at the time of the observation.Conclusions.Assuming the detected signals are real, we discuss their potential origin. Their source probably is theτBoötis planetary system, and a possible explanation is radio emission from the exoplanetτBoötis b via the cyclotron maser mechanism. Assuming a planetary origin, we derived limits for the planetary polar surface magnetic field strength, finding values compatible with theoretical predictions. Further observations with LOFAR-LBA and other low-frequency telescopes, such as NenuFAR or UTR-2, are required to confirm this possible first detection of an exoplanetary radio signal.
Populations of super-soft X-ray sources in galaxies of different morphological types
Authors: Galiullin I. , Gilfanov M. 
Published: December 2020

Aims. We study populations of soft and super-soft X-ray sources (SSSs) in nearby galaxies of various morphological types with particular emphasis on characterizing populations of stable nuclear burning, accreting white dwarfs (WDs).
Methods. Analyzing the content of the Chandra archive, we assembled a sample of nearby galaxies suitable for studying populations of SSSs. Our sample includes four spiral galaxies, two lenticular galaxies, and three ellipticals with stellar mass exceeding 1010 M⊙ and X-ray sensitivity of the order of a few × 1036 erg s−1. We used a combination of hardness ratio and median energy to pre-select X-ray sources with soft spectra, and used the temperature–X-ray luminosity diagram to identify SSSs, likely nuclear-burning, accreting WDs.
Results. For spiral galaxies, there is a distinct and rare population of super-soft sources that are largely detached from the rest of the sources on the kTbb − LX plane. The boundary between these sources and the much more numerous population of harder (but still soft) sources is consistent with the boundary of stable hydrogen burning on the surface of WDs. The combined spectrum of soft sources located outside this boundary shows clear emission lines of Mg and S, the equivalent width of which is similar to that in the combined spectrum of a large number of confirmed supernova remnants in M 83. This supports earlier suggestions that the vast majority of the so-called quasi-soft sources are supernova remnants. In early-type galaxies, populations of super-soft sources are about a factor of eight less abundant, in broad agreement with the population synthesis calculations. Specific frequencies of super-soft sources are (2.08 ± 0.46) × 10−10 M⊙−1 in spiral galaxies and (2.47 ± 1.34) × 10−11 M⊙−1 in lenticular and elliptical galaxies, with the ratio of the latter to the former being 0.12 ± 0.05.
Comprehensive rotational study and astronomical search for cyclopropanecarboxaldehyde
Authors: Cabezas C. , Neeman E. M. , Tercero B. , Bermúdez C. , Cernicharo J. 
Published: December 2020

Context. At least a dozen molecules with a formyl group (HCO) have been observed to date in the interstellar medium (ISM), suggesting that other such species exist and remain to be discovered. However, there is still a lack of high-resolution spectroscopic data for simple molecular species of this type that could provide a basis for their detection.
Aims. Cyclopropanecarboxaldehyde, c-C3H5CHO, is a small molecule containing a formyl group and is therefore an interesting candidate for astrophysical detection. The rotational spectrum of cyclopropanecarboxaldehyde has been observed before, but its experimental rotational parameters are not precise enough to allow its detection in the millimetre-wave domain.
Methods. We measured the rotational spectrum of cyclopropanecarboxaldehyde in the frequency ranges 31.5–50 GHz and 72–116.5 GHz using the GACELA (GAS CEll for Laboratory Astrophysics) broadband high-resolution rotational spectrometer constructed at the Yebes Observatory. The spectroscopic study was supported by high-level theoretical calculations which were used in the identification of the vibrational excited states of cyclopropanecarboxaldehyde.
Results. Our analysis of the rotational spectrum of cyclopropanecarboxaldehyde allowed us to obtain accurate rotational parameters for the ground state of both cis and trans isomers, which were used to derive sufficiently reliable predictions up to 300 GHz. In addition to the ground states, we identified 12 and 6 vibrationally excited states for the trans and cis isomers, respectively, including fundamental modes, multiple excitation quanta, and combination states. We find that the gas phase concentration of the trans isomer is almost 1.2 times larger than that of the cis one. These new experimental rotational parameters were employed to search for cyclopropanecarboxaldehyde in the warm molecular clouds Orion KL and Sgr B2(N) using the spectral surveys captured by ALMA (Orion) and IRAM 30 m (Sgr) at 1 and 3 mm, respectively.
Gicht: aktuelle Epidemiologie, Komorbiditäten, Komplikationen
und sozioökonomische Konsequenzen
Authors: Kiltz Uta , Buschhorn-Milberger Verena , Vaupel Kristina , Braun Jürgen 
Published: December 2020

ZusammenfassungDie Gicht gehört neben der rheumatoiden Arthritis zu den
häufigsten Ursachen von Gelenkentzündungen. Als metabolisch
bedingte Erkrankung geht sie meist mit Hyperurikämie und der
Ablagerung von Uratkristallen in Gelenken, Sehnen und Weichteilgeweben
einher, wodurch Entzündungszustände ausgelöst werden
können. Die Gichtarthritis tritt weltweit insbesondere in den
Industrieländern mit steigender Prävalenz auf (weltweit
0,6%), wobei die größte Häufigkeit bei den
Maoris in Ozeanien (bis zu 10%) gemessen wurde. In Deutschland tritt
die Gicht altersabhängig mit einer Prävalenz von
1,63% auf, wobei Männer ungefähr dreimal so
häufig wie Frauen betroffen sind. Kardiovaskuläre und vor
allem renale Komorbiditäten können zu vermehrten
Komplikationen und einer erhöhten Sterblichkeit von Patienten mit
Gicht führen. Grundsätzlich haben Gichtpatienten eine
erhöhte Mortalität im Vergleich zur
Gesamtbevölkerung. Die zunehmende Inzidenz führt zu
steigenden Gesundheitskosten, besonders durch vermehrte Hospitalisierungen.
Darüber hinaus wurden bei Gichtpatienten mehr
Arbeitsunfähigkeitstage sowie reduzierte Erwerbsfähigkeit
mit entsprechenden volkswirtschaftlichen Konsequenzen nachgewiesen.
Curative Evidence of Individualised Homoeopathic Treatment in a Case of Alopecia Areata
Authors: Sahoo Amulya Ratna , Khanra Joydeep , Choubey Gurudev , Banerjee Abhiram 
Published: December 2020

Abstract
Introduction Alopecia areata is an auto-immune disorder, suffered by almost 2% of world's population, characterised by non-scarring patches over the scalp. Clinical heterogeneity along with an unpredictable course and history make this disease difficult to treat.
Patient Information A 19-year-old unmarried female reported with complain of loss of hair from a patch on the top of her head; she experienced gradual increase in falling of hair for past 4 years that resulted in complete patchy baldness over the vertex. She tried all sorts of treatment but failed and was advised for hair transplantation, which she could not afford.
Result She has been treated successfully by homoeopathic single medicine Graphites. Over the period of 5 months of homoeopathic treatment, complete resolution was observed. Documentation was done in the form of photographs from the same angle under similar light exposure in every follow-up. Patient's perspective was assessed in each follow-up visit using ORIDL—Outcome in Relation to Impact on Daily Living—scale, and causal attribution of the case has been determined using the modified Naranjo criteria.
Discussion and Conclusion Individualised homoeopathic intervention may be a potential alternative in treatment of alopecia, though further research with better methodology is suggested.
A Rare Case of Joint Infection due to Raoultella planticola
Authors: Ismair Kevin , Abdeen Yazan 
Published: December 2020

Abstract
Raoultella planticola, a gram-negative bacterium, first emerged in late 1900s as Klebsiella planticola. It was later classified as Raoultella genus in 2001. This nonmotile rod is usually found in soil and aquatic environment. There are two known species of Raoultella: R. planticola and R. ornithinolytica. They are responsible for numerous yet rare infections including cystitis, pneumonia, and bacteremia. To date, only one case of joint or bone infection due to R. planticola has been reported. The infection is eradicated after arthroscopic lavage and antibiotic therapy with fluoroquinolones. We present the first case of septic arthritis due to R. planticola involving a native knee joint following synovectomy during arthroscopy.