bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Tindakan Pencegahan Ibu dengan Kejadian Diare pada Balita
Authors: Hendrastuti Carita Bidari 
Published: January 2020

Latar Belakang: Setiap tahun 6 juta anak kehilangan nyawa yang disebabkan oleh kasus diare. Sebagian kematian tersebut terjadi di negara berkembang. Data dari Dinas Kesehatan Kota Surabaya menyebutkan bahwa jumlah kasus diare sebanyak 65.447 yang telah di tangani pada tahun 2015. Sedangkan tahun 2017 di Puskesmas Sidotopo yang membawahi kelurahan Ampel terjadi kasus diare sebanyak 611 kasus. Tujuan: Penelitian ini untuk mengetahui hubungan perilaku ibu dengan kejadian diare pada balita. Metode: Populasi adalah seluruh ibu balita di RT 2-3 RW XIII dan RT 1 RW XIV Kelurahan Ampel Kecamatan Semampir Kota Surabaya. Jenis penelitian adalah kuantitatif dengan design cross sectional. Pengambilan sampel penelitian dalam penelitian ini adalah menggunakan metode Slovin dengan teknik simple random sampling. Jumlah populasi sebanyak 55 ibu dengan besar sample 35 responden. Hasil: Dua variabel menunjukkan hasil yang signifikan. Ada hubungan yang signifikan antara penyimpanan air minum di tempat yang bersih dan tertutup dengan kejadian diare pada balita (p value = 0,021). Ada hubungan yang signifikan antara pemberian ASI Eksklusif dengan kejadian diare pada (p value= 0,048). Perilaku cuci tangan pakai tidak berhubungan dengan kasus diare pada balita di Kelurahan Ampel. Kesimpulan: Faktor yang berpengaruh terhadap kejadian diare di Kelurahan Ampel adalah penyimpanan air minum di tempat yang bersih dan tertutup serta pemberian ASI Eksklusif.
Angry, Hungry T-Cells: How Are T-Cell Responses Induced in Low Nutrient Conditions?
Authors: Nicoli Francesco 
Published: January 2020

Abstract
Upon activation, T-cells increase the uptake of glucose and glutamine to build the constituents of proliferating effectors. However, tumor and infected cells compete for the same nutrients. Several observations are consistently indicating that activated T-cells overcome this situation by engaging catabolic pathways. Here I discuss how these observations are reconciled with T-cells’ need of anabolic processes during activation.
IMPACT RESILIENCE: ECOLOGICAL RECOVERY OF A CARBONATE FACTORY IN THE WAKE OF THE LATE DEVONIAN IMPACT EVENT
Authors: RENDALL BENJAMIN E. , TAPANILA LEIF 
Published: January 2020

ABSTRACT
Conformable limestone deposits bracketing the Alamo breccia (Late Devonian, Nevada) provide a robust dataset for comparisons of depositional environments and marine communities before and after a significant meteor impact. Rank abundances of more than 3000 faunal identifications from 158 sampling localities cluster in three major faunal groups that are arranged in an onshore-offshore lithofacies gradient. Comparison of faunal clusters before and after the impact show little to no dissimilarity. The recovery of marine invertebrate communities following the Alamo impact event was geologically instantaneous. Broad geographic ranges of the fauna may have contributed to ecological resilience. From a geologic perspective, marine communities appear to rebound quickly and fully following meteor impacts, leaving impact-related extinctions as outliers that correspond only to the largest impacts.
The use of botulinum toxin for the treatment of patients with overactive bladder
Authors: Licow Agnieszka , Ciećwież Sylwester , Ptak Magdalena , Kotlęga Dariusz , Starczewski Andrzej , Brodowska Agnieszka 
Published: January 2020

AbstractOveractive bladder affects 12–17% of the population, and mainly women, and its incidence increases with age. Diagnosis of this condition is based mainly on the patients’ complaints. These symptoms significantly affect the quality of life of millions of patients, involving considerable social, psychological, professional, physical and sexual problems. The wide incidence of this condition makes it necessary to find new medical substances in order to effectively eliminate the symptoms. Neurotoxins are a group of medical drugs that hold great promise for the future. Botulinum toxin is currently being used to treat symptoms related to overactive bladder. It can constitute an appropriate therapeutic option, in particular with regard to patients for whom the use of standard anti-cholinergic drugs is unsatisfactory or leads to severe side effects. Numerous research studies confirm that botulinum toxin can be efficiently used in the treatment of overactive bladder. The properties of this neurotoxin allow selective deactivation of overactive muscles. The use of botulinum toxin can be a method of treatment that significantly improves patient quality of life.
Localization of paresthesia in patients with carpal tunnel syndrome
Authors: Puchalski Piotr , Abramczyk Urszula , Dziubiński Dawid , Jedut Wojciech , Żyluk Andrzej 
Published: January 2020

Abstract

Introduction: Paresthesia (numbness, tingling, “pins and needles” sensation) and pain in the hand comprise a typical set of symptoms of carpal tunnel syndrome. Most authors consider a typical occurrence of these features within the palmar surface of digits I–IV, innervated by a compressed median nerve. Observations of patients by various authors show that some patients feel pares-thesia in all digits of the affected hand and within the forearm. The objective of this study was investigation of the distribution of paresthesia in patients diagnosed with carpal tunnel syndrome, and verification of the hypothesis that this occur-rence in areas beyond the innervation by the median nerve is an atypical manifestation of the syndrome.

Materials and methods: Questionnaires and notes filled out during baseline examination of 276 patients admitted to authors’ institution for carpal tunnel release over a period of 1 year were reviewed. The group consisted of 211 women (76%) and 65 men (24%) at a mean age of 59 years.

Results: Two hundred seventy-four patients (99%) reported feeling paresthesia within the involved extremity, and 2 did not, but complained of pain and reduced sensation. Most patients – 140 (51%) – felt paresthesia on the palmar surface of all 5 digits, including the little finger. Seventy-eight persons (28%) reported a “typical” distribution of paresthesia within digits I–IV and 31 (11%) in digits I–III. As many as 152 patients (55%) felt paresthesia in the little finger, most of them being cases with numbness and tingling present in all 5 digits. The feeling of paresthesia in the midhand, close to the involved digits was reported by 158 patients (57%).

Conclusion: We found that the distribution of symptoms in carpal tunnel syndrome does not closely match the anatomy of the median nerve and this presentation should no longer be considered atypical.
The role of microRNAs in angiogenesis
Authors: Bujak Joanna , Kopytko Patrycja , Lubecka Małgorzata , Sokołowska Katarzyna , Tarnowski Maciej 
Published: January 2020

Abstract
Angiogenesis is the process that leads to the formation of new blood vessels. Under physiological conditions it occurs, inter alia, during corpus luteum formation and in some stages of the menstrual cycle. However, angiogenesis plays an essential role in many pathological conditions, particularly cancer. New blood vessel formation provides cancer cells with oxygen and essential nutrients, which stimulates tumor growth and facilitates its metastasis. Increasing evidence indicates that angiogenesis is regulated by microRNAs (miRNAs), which are small non-coding RNA molecules of 19–25 nucleotides. The main function of miRNAs is post-transcriptional regulation of gene expression, which controls many key biological processes, including cell proliferation, differentiation and migration. Endothelial miRNAs, known as angiomiRs, are presumably involved in tumor development and angiogenesis through regulation of pro- and antiangiogenic factors. To date, the miRNAs that stimulate angiogenesis are: miR-9, miR-27a, miR-30d, miR0-130b, miR-139, miR-146a, miR-150, miR-155, miR-200c, miR-296 and miR-558. Conversely, miRNAs that inhibit angiogenesis are: miR-145, miR-519c, miR-22, miR-20a, miR-92, miR-7b, miR-221, miR-222, miR-328 and miR-101.
Professional competences in family nurse practitioners in North-Western Poland
Authors: Kęcka Katarzyna 
Published: January 2020

Abstract

Introduction: Professional nursing is increasingly often understood as accompanying and assisting people during health, disease and limited fitness. It is also shaping their self-care capabilities. The complexity of these tasks puts great responsibility on nurses, since they are those health care professionals who are in direct contact with patients’ families and communities. Nurses’ functions are exceptional because they involve the management and organization of holistic care in work with patients and their families (nursing and educational activities, cooperation with other members of a therapeutic team).
The purpose of this study was to analyze their level of knowledge concerning their tasks and professional competences in family nurse practitioners employed in primary health care centers.

Materials and methods: The research were carried out from February 2014 to the end of October 2015 in entities providing nursing services in primary health care in north-western Poland. For the analysis 643 questionnaire surveys were accepted.

Results: Family nurse practitioners in north-western Poland show a satisfactory level of knowledge in the field of professional competence. Nurses have especially high levels of knowledge concerning patients’ access to nursing services, information provided by primary care physicians as part of cooperation in the care of a patient, the nursing process method, and care of elderly and chronically ill individuals. The nurses had gaps in their knowledge of selected nursing services, such as bladder irrigation, transport, and rectal procedures. Alarmingly low levels of knowledge were observed with regard to professional competence in the care of patients with mental diseases.
Kinematic and Mechanical Analysis of the Ankle Rotating-Traction-Poking Manipulation
Authors: Chunyu Gao , Baojian Wang , Liguo Zhu , Gao Jinghua , Jianguo Li , Jian Li , Minshan Feng 
Published: January 2020

Abstract
Background: In China, the ankle rotating-traction-poking manipulation (RTPM) has been used to increase range of movement and reduce pain in patients with lateral ankle sprains. But no research so far has quantitatively analyzed the kinematic and mechanical data of RTPM therapy. Therefore, the purpose of the present study was to analyze the kinematics and mechanics of RTPM technique.
Methods: A total of 60 volunteers who had ankle sprains participated in the study. A single physiotherapist specializing in RTPM worked with each of the subjects. Motion capture technology, self-developed mechanical gloves, and a data synchronization device were used to acquire kinematic and mechanical data during the RTPM.
Results: The mean maximum force of the thumb, index finger, and middle finger during the rotating was 18.89 N, 10.26 N, and 9.51 N, respectively, that of the traction force was 18.61 N, 13.25 N, and 8.33 N, respectively, and that of the poking force was 26.5 N, 8.61 N, and 10.62 N, respectively. The average time of rotating for six circles was 11.36 s. The average linear velocity of rotating was 58.28 mm/s, and that of traction-poking was 23.81 mm/s. The average linear acceleration of rotating was 0.43 mm/s2, and that of traction-poking was 0.54 mm/s2. The average displacements of traction and poking were 36.94 mm and 22.44 mm, respectively. The average angle of traction and poking were 23.27° and 22.76°, respectively.
Conclusions: The RTPM can be repeatable for clinical application, and also has features of gentleness, rhythmicity, and continuity.
Herbal medicine use and its associated factors among pregnant women attending antenatal care at Wollega University Referral Hospital, West Ethiopia.
Authors: Labata Busha Gamachu , Wakjira Getu Bayisa , Dedefo Mohammed Gebre , Mekonen Ginenus Fekadu , Golja Eba Abdisa , Jaleta Dessalegn Dereje 
Published: January 2020

Abstract
Background: Herbal medications are plant-derived materials or products with therapeutic or other human health benefits, which contain either raw or processed ingredients from one or more plants. There are many different types of herbal medicine that spring from different cultures around the world. All these have the use of medicinal plants in common. Developing world general population relies on these traditional medicines for primary care. Besides, pregnant women use herbal medicines because of pregnancy related ailments and normal aliments. Therefore, the study aimed to assess prevalence and factors associated with herbal medicine use among pregnant women attending antenatal care at Wollega University Referral Hospital. Method: A facility based cross sectional study was conducted among pregnant women attending Wollega University Referral Hospital antenatal care from May to June 2018. Written informed consent was obtained from study participants prior to data collection. Univariate and Multivariate logistic regression analysis was used to determine factors associated with herbal medicine use. Association was significant when p-value is less than 0.05. Result: A total of 238 pregnant mothers were participated in the study. The respondents’ age ranges from 17 to 46 years. The prevalence of herbal medicine use among pregnant women attending antenatal care at Wollega University Referral Hospital was 66.40%. The use of herbal medicine during pregnancy was 3.885 times more likely among rural residents (AOR =3.885, 95% CI 1.121-13.47) than urban residents. Respondents who has monthly income between 1001 to 2000 Ethiopian Birr (AOR=2.585, 95% CI 1.125–5.940) were 2.585 times more likely to use Herbal medicine as compared to those who earn >3000 Ethiopian Birr. However, mothers of planned pregnancy (AOR=0.335, 95% CI 0.114-0.986) were less likely to use Herbal medicine as compared to those who had unplanned pregnancy. Conclusion: The prevalence of herbal medicine use among pregnant women attending antenatal care at Wollega University Referral hospital was 66.40%. Commonly used herbs were Garlic (24.37%) and ginger (18.07%). Rural residence and low income had significantly associated to herbal medicine use while planned pregnancy was inversely associated to herbal medicine use.
Complete protection for mice conferred by a DNA vaccine based on Japanese encephalitis virus P3 strain that is used to prepare the inactivated vaccine in China
Authors: Wang Ran , Yu Xiaozheng , Wang Yan , Zheng Xiaoyan 
Published: January 2020

AbstractBackground The incidence of Japanese encephalitis (JE) has been dramatically reduced in China after the coverage of the vaccine. It is believed that the live-attenuated Japanese encephalitis virus (JEV) vaccine SA14-14-2 has contributed a lot. Another vaccine that seems to have faded out of the public is an inactivated vaccine based on the JEV P3 strain, which is still considered to have certain modifiability, such as being transformed into a DNA vaccine to improve its immunogenicity. Methods In this study, the protective efficacy induced by a Japanese encephalitis DNA vaccine candidate pV-JP3ME encoding pre-membrane (prM) and envelope (E) proteins of P3 strain in BALB/c mice. The prM/E genes of the JEV P3 strain were subcloned into vector pVAX1 (pV) to construct pV-JP3ME. Results The plasmid DNA was immunized BALB/c mice, high titers of IgG antibody and neutralizing antibody (nAb) against JEV were detected. The key cytokines in splenocytes upon stimulation with JEV antigens were secreted. Finally, complete protective efficacy was generated after challenge with the JEV P3 strain in mice. Conclusions The DNA vaccine pV-JP3ME based on JEV P3 strain in this study can induce specific humoral immune and cytokine responses in mice, and provide complete protection for mice against JEV.
Metallothionein alone or in combination with Prussian blue attenuates acute thallium systemic toxicity in rats.
Authors: Anaya-Ramos Laura , Díaz-Ruíz Araceli , Ríos Camilo , Montes Sergio , Aguirre-Vidal Yoshajandith , García-Jiménez Sara , Baron-Flores Veronica , Monroy-Noyola Antonio 
Published: January 2020

Abstract
Background: Acute Thallium (Tl) toxicosis is still a health problem, worldwide. Oral administration of Prussian blue (PB) is the antidotal treatment of election. On the other hand, metallothionein (MT) is a low-molecular-weight protein, with high content of cysteines (25–30%). MT is able to chelate metals as an efficient endogenous mechanism of detoxification. It is also a potent antioxidant. Methods: In this study, we tested the ability of MT at two doses (100 and 600 µg/rat), administered alone or in combination with Prussian blue (PB) (50 mg/kg) to decrease thallium (Tl) toxicity. A sublethal dose of Tl (16mg/kg) was injected i.p. to male Wistar rats. Antidotes were administered twice-daily, starting 24h after Tl injection, for 4 days. Tl concentrations were analyzed in body organs and brain regions, 5 days after Tl injection. Results: Results showed a diminution (p<0.05) of Tl concentrations in all organs by effect of PB alone or in combination with MT-100 and MT-600, whereas MT-100 only decreased Tl concentrations in testis, spleen, lung and liver. Likewise, Tl in brain regions was also diminished (p<0.05) by effect of PB and both MT-100 alone or in combination in most of the regions analyzed (p<0.05). The greatest diminution of Tl was achieved when the antidotes were combined. Plasma markers of renal damage, increased after Tl administration. Both PB and MT, either alone or in combination, prevented the raise of renal markers of Tl Toxicity. Conclusions: Our findings demonstrate that the combined treatment of PB + MT is a good antidotal option against thallotoxicosis.
Bacterial&nbsp;Resistance&nbsp;and&nbsp;Antisseptic&nbsp;Effects&nbsp;on&nbsp;the&nbsp;Eye&nbsp;Surface&nbsp;of&nbsp;Donor&nbsp;Corneas
Authors: Ito Célia , Silva Carla , Carneiro Lilian Carla , Barbosa Mônica , Neto José , Messias Aline , Feitosa Ana , Santos Adailton , Queiróz Pedro , Monteiro janaina , Santos Andressa , Avila Marcos 
Published: January 2020

Abstract
BackgroundThe antiseptic solutions most used by Eye bank or in ophthalmologic surgeries are polyvinylpyrrolidone-iodine and gluconate of chlorhexidine. Objetives: The objective of this study was to evaluate the antiseptic effect in the reduction of ocular globe microbiota from corneal donors, as well as to analyze the susceptibility of the microbiota to gentamicin. MethodsThirty pairs of corneas received antiseptics, with Povidone-iodine in the right eye and gluconate of chlorhexidine in the left eye, and for each time of action (5, 10 and 15 minutes), totalling three groups, and using 10 pairs of eyeballs to each group. Swabs were collected from the ocular surface prior to application of the solutions, after and at the time of preservation of the corneal tissue. After identification of the microbiota, an antibiogram test with gentamicin was performed. ResultsRegarding the data obtained in the second group, after the use of antiseptics, there was a reduction of 40% in the total of gram positive bacteria and a reduction of 75.9% to gram negative bacteria, the results shows that in the second group, both antiseptics were more effective to Gram negative bacteria. The third group results show the residual effect of antiseptics and there was a reduction of 99.1% of all micro-organisms. To the antibiogram test, 88% of the microorganisms isolated, were sensitive to gentamicin. ConclusionWas observed that using the tested concentration to each antissepetic, there are no action differences to descontamination between the two products, there was not differences between the action time too. Key-words: eye bank, enucleation, povidone-iodine, gluconate of chlorhexidine, transplantation.
First report of Blastocystis infection in pigs from large-scale farms in Xinjiang, China
Authors: Wang Rongjun , Zhang Ying , Jiang Yuxi , Xing Jinming , Tao Dayong , Zhang Longxian , Qi Meng 
Published: January 2020

Abstract
Background: Blastocystis is a commonly identified intestinal protozoan in humans and various animals. Few studies are available regarding the genetic characterization of Blastocystis infections in pigs in China. Methods: In this study, 801 fecal samples were collected from seven large-scale pig farms in Xinjiang and tested by polymerase chain reaction. Results: The average infection rate of Blastocystis was 21.7% (174/801); the infection rates for pre-weaning piglets, post-weaning piglets, fattening pigs, and sows were 7.1%, 10.0%, 31.8%, and 41.9%, respectively (χ 2 = 104.89; P < 0.01). Blastocystis subtypes ST1 ( n = 7), ST3 ( n = 2), and ST5 ( n = 165) were identified using sequence analysis of the small-subunit ribosomal RNA gene, with subtype ST5 being predominant in each of the pig farms. All the age groups were positive for Blastocystis . ST3 and ST5 were identified in pre-weaning piglets, and ST1, ST3, and ST5 in post-weaning piglets. In contrast, only the ST5 subtype was observed in fattening pigs and sows. Genetic polymorphisms were observed at the intra-subtype level, including two variations for ST1 (ST1A, ST1B), and seven for ST5 (ST5A to ST5G), by sequence alignment analysis and phylogenetic analysis. Conclusions: A high prevalence of Blastocystis was detected in pigs in Xinjiang, China. The infection rate increased significantly with increasing age of the pigs. ST5 was the predominant Blastocystis subtype in all age groups. Subtypes ST1, ST3, and ST5 may emerge as zoonotic pathogens in some areas of China because of the large scale of the pork industry and close contact between pigs and humans. More studies are needed to elucidate the transmission and public health significance of Blastocystis in pigs in various areas. Key words: Blastocystis , SSU rRNA, genetic polymorphism, pig, Xinjiang
Molecular detection of tick-borne haemopathogens in shelter dogs and Rhipicephalus sanguineus (sensu lato) ticks from Peninsular Malaysia
Authors: Sipin Quincie , Kamal Farina Mustaffa , Watanabe Malaika , Rani Puteri Azaziah Megat Abdul , Md Nur Mahiza , Aziz Nor Azlina Abdul 
Published: January 2020

Abstract

Background Canine tick-borne haemopathogens (TBH) constitute a significant concern worldwide. The detection of these TBH is mainly achieved by microscopic evaluation, seroprevalence, and molecular detection. The present study was designed to investigate the molecular detection of Anaplasma platys ,Babesia gibsoni, Babesia vogeli, andEhrlichia canisin shelter dogs andRhipicephalus sanguineus ( sensu lato )ticks infesting them in Malaysia.Results A total of 220 blood samples and 140 ticks were collected from 10 animal shelters in Peninsular Malaysia. The presence of haemopathogens was detected using conventional PCR, sequenced, and identified at the species level. Of the 220 blood samples, 77 (35%) were positive with at least one of the four haemopathogens, of whichE. canispredominated (20%) followed by B. gibsoni andB. vogeliboth with detection of 7%, andA. platys(12%). In tick samples, 5 (3.57%) of the collected samples were positive with at least one of the three haemopathogens. Low detection ofE. canisand A. platys were present (n = 2; 1.43%) as well asB. vogeli﻿shows only 1 sample positive (0.71%) and no detection of B. gibsoni . For co-infection in dogs, single infection is common (24%), while co-infection with two haemopathogens (10%) was also observed. The occurrence of infection with three TBH was also observed in the sampled dogs (1%).ConclusionE. canisis the most common TBH affecting shelter dogs in Peninsular Malaysia. Co-infection is quite common and the most common co-infection present wasE. canisandA. platys. The study highlighted the first extensive molecular detection of TBH in dogs and R. sanguineus ( sensu lato ) ticks in Malaysia