bluuebunny/crossref_metadata_2025_split huggingface dataset:
A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation
Authors: Cayla Mathieu , Matthews Keith R. , Ivens Alasdair C. 
Published: September 2020

Background: Low-complexity regions (LCRs) on proteins have attracted increasing attention recently due to their role in the assembly of membraneless organelles or granules by liquid-liquid phase separation. Several examples of such granules have been shown to sequester RNA and proteins in an inactive state, providing an important mechanism for dynamic post-transcriptional gene regulation. In trypanosome parasites, post-transcriptional control overwhelmingly dominates gene regulation due to the organisation of their genome into polycistronic transcription units. The purpose of the current study was to generate a substantially more comprehensive genome-wide survey of LCRs on trypanosome proteins than currently available. Methods: Using the Shannon’s entropy method, provided in the R package ‘entropy’, we identified LCRs in the proteome of Trypanosoma brucei. Our analysis predicts LCRs and their positional enrichment in distinct protein cohorts and superimposes on this a range of post-translational modifications derived from available experimental datasets. Results: Our results highlight the enrichment of LCRs in the C-terminal region of predicted nucleic acid binding proteins, these acting as favoured sites for potential phosphorylation. Conclusions: The post-translational modifications of LCRs, and in particular the phosphorylation events, could contribute to post-transcriptional gene expression control and the dynamics of protein targeting to membraneless organelles in kinetoplastid parasites.
A Experiência Drag Queen como Transição na Vida Adulta
Authors: Ferreira Ligia Ribeiro , Aléssio Renata Lira dos Santos 
Published: September 2020

A partir de reflexões teóricas impulsionadas pela Rede de Significações (RedSig) e Teorias de Gênero, o presente trabalho teve como objetivo investigar sentidos e significados tecidos sobre a experiência como drag queen na vida adulta. A metodologia utilizada teve base em entrevistas biográficas, realizadas com cinco participantes, entre 20 e 39 anos, que têm ou já tiveram experiência como drag queens. Para a análise, foi realizada uma abordagem microgenética, correlacionando elementos da RedSig com as narrativas. Os resultados indicaram que a vida adulta não aparece como percurso linear, sendo permeada por rupturas, conflitos e negociações de sentidos e posições. A vida adulta se torna o palco no qual é possível ocupar determinados espaços de poder para colocar em prática desejos e curiosidades que, por vezes, remontam à infância. A drag queen emerge como um elemento relacionado a esse processo, atrelada a diversos sentidos e significados positivos (arte, realização, liberdade) e negativos (vergonha, preconceito, degradante).
Design and analysis of full-scale scanning system for curved glass based on motion and 3D features
Authors: Wang Peng , Fan Yulin , Chen Guodong , Chi Wenzheng , Wang Zhenhua , Sun Lining 
Published: September 2020

In recent years, mobile phones with glass curved screens have become more and more widely used. The irregular shape of the curved screen and the light transmittance characteristic of the glass have brought great challenges to its automatic defect detection. Aiming at the defect detection of the glass cover of the curved screen, this paper designs a full-scale scanning system by combining motion and three-dimensional (3D) features. First, a scanning system is constructed, and a geometric error modeling method is proposed to improve the accuracy of the scanning system; second, based on the point cloud of the 3D glass cover obtained by the scanning system, a point cloud registration method is presented by integrating the motion and 3D features; finally, the laser tracker is further used to calibrate the scanning system to analyze the mechanical error. Experimental results show that the introduction of straightness error and perpendicularity error can effectively solve the mismatch and fault problems of point cloud registration, and improve the accuracy of the scanning system. In addition, the registration method proposed in this paper can effectively reconstruct the complete point cloud of 3D glass cover for detection. The reconstruction accuracy of the plane part can reach 0.031 mm, and that of the curved part can reach 0.091 mm.
Ultracompact silicon polarization splitter-rotator using a dual-etched
and tapered coupler
Authors: Xie Changjian , Zou Xihua , Li Peixuan , Yan Lianshan , Pan Wei 
Published: September 2020

The polarization splitter-rotator (PSR) plays a significant role in
telecom, Datacom, and quantum circuits to meet significant
requirements for polarization processing and multiplexing. We design
an ultracompact PSR based on a silicon asymmetrical directional
coupler (ADC). One waveguide of the ADC is gradually etched in two
levels along the coupling region and the S-bend. A trapezoidal taper
on the top of the dual-etched waveguide is first formed to satisfy the
phase-matching condition for the TM-TE mode conversion, such that the
TM mode is cross-coupled from the input waveguide without etching.
Then, the etching width gradually increases in the S-bend and the
following to achieve a single-mode waveguide for further removal of
the residual TM mode. In this way, a high extinction ratio can be
achieved for the polarization mode splitting in an ultracompact
silicon ADC. For the designed PSR with a total length of about 24 µm,
the simulation results reveal that the minimum extinction ratio is
greater than 30, 20, or 15 dB within the bandwidth of 33, 100, or
150 nm, respectively, while the maximum polarization conversion loss
is less than 0.4, 0.9, or 1 dB.
High azimuthal angle tolerant dual-channel wavelength filter from visible to NIR using conically mounted guided mode resonance structures
Authors: Sahoo Pankaj K. , Sharma Jaiyam , Yukino Ryoji , Sandhu Adarsh , Joseph Joby 
Published: September 2020

We present a concept to design narrow linewidth dual-channel wavelength filters using the principle of wavelength tuning under conical mounting of guided mode resonance structure. The general procedure for the design of such filters from visible to NIR wavelength range is presented and validated experimentally. We show that already fabricated guided mode resonance structures that do not show dual wavelength filtering at these wavelengths in classical mounting can exhibit dual wavelength filtering in conical mounting. Using this principle, we design high azimuthal angle tolerant guided mode resonance dual wavelength filters at C-band communication wavelengths (1310 and 1550 nm) that are insensitive to azimuthal angle over a range of up to 20 deg, achieved in expense of a tolerance in the angle of incidence that is less than 3 deg.
A Preclinical Animal Study of Combined Intragastric Balloon and Duodenal-Jejunal Bypass Liner for Obesity and Metabolic Disease
Authors: Ghoz Hassan , Jaruvongvanich Veeravich , Matar Reem , Beran Azizullah , Maselli Daniel B. , Storm Andrew C. , Abu Dayyeh Barham K. 
Published: September 2020

INTRODUCTION:
Endoscopic bariatric and metabolic therapies can potentially reproduce similar gastric and small intestinal anatomic and physiologic manipulations as Roux-en-Y gastric bypass. This proof of concept animal study was aimed to assess the feasibility, safety, efficacy, and impact on gastrointestinal physiology of combined intragastric balloons (IGB) and duodenal-jejunal bypass liner (DJBL) for the treatment of obesity.

METHODS:
Five Ossabaw pigs were fed a high-calorie diet to develop obesity and were randomly assigned to receive IGB or DJBL in sequence. The weight gain rate was calculated. Fasting and postprandial blood samples were drawn before any intervention (serving as the baseline group) and 1 month after second device insertion (serving as the combination group) to measure gut neurohormonal changes and metabolic parameters.

RESULTS:
Four pigs successfully received a sequential device insertion. One pig developed duodenal sleeve prolapse that was spontaneously resolved. One pig was early terminated because of developing a central line infection. The rate of weight gain in the combination group (0.63 ± 1.3 kg/wk) was significantly lower than the baseline group (1.96 ± 2.17 kg/wk) and numerically lower than after insertion of the IGB (1.00 ± 1.40 kg/wk) or the DJBL (0.75 ± 2.27 kg/wk) alone. A trend of higher postprandial glucagon-like peptide-1 was observed in the combination group compared with the baseline group.

DISCUSSION:
A combination of IGB and DJBL is feasible and well tolerated. A strategy of sequential use of these devices might offer a synergistic approach that can enhance weight loss and metabolic outcomes.
Randomised trial of block and replace vs dose titration thionamide in young people with thyrotoxicosis
Authors: Wood Claire L , Cole Michael , Donaldson Malcolm , Dunger David B , Wood Ruth , Morrison Niamh , Matthews John N S , Pearce Simon H S , Cheetham Timothy D , _ _ 
Published: September 2020

Objective
First-line treatment of thyrotoxicosis in young people is thionamide anti-thyroid drug (ATD) in a blocking dose with levothyroxine replacement (block and replace, BR) or in a smaller dose tailored to render the patient euthyroid (dose titration, DT). Our objective was to determine which regimen provides more stable biochemical control.

Design
A multi-centre phase III, open-label randomised trial comparing BR with DT in patients aged 2–17 years with newly diagnosed thyrotoxicosis at 15 UK centres.

Methods
Patients were randomised shortly after diagnosis and treated for 3 years. The primary outcome was the percentage of serum thyroid-stimulating hormone (TSH) levels in the reference range between 6 months and 3 years. Secondary outcomes included the proportion of Free thyroxine (FT4) levels in the reference range, adverse event frequency and 4 years outcome (remission/relapse).

Results
Eighty-two patients were randomised, with details on clinical course in 81 (62 Female); 40 were allocated to BR (41 DT). Three withdrew with one ineligible. The mean percentage of serum TSH within reference range was 60.2% in BR and 63.8% in DT patients; adjusted difference 4.3%, 95% CI (−7.8 to 16.4); P = 0.48. Proportions for FT4 were 79.2% in BR and 85.7% in DT patients; adjusted difference 6.8%, (−0.2 to 15.6); P = 0.13. Three patients developed neutropenia – all on BR. 6 BR and 10 DT patients were in remission at 4y.

Conclusion
This randomised trial has shown no evidence to suggest that BR, when managing the young patient with thyrotoxicosis, is associated with improved biochemical stability when compared to DT.
Interpretasi Semiotika Ferdinand De Saussure dalam Hadis Liwa dan Rayah
Authors: Habibi M Dani 
Published: September 2020

This article is a study evaluating the Hadith interpretation in flag Rayah and Liwa or the flag of monotheism. In Indonesia, an organization that uses the banner of Tawheed is the symbol of the organization Hizbut Tahriri Indonesia. There are two warana flag that is black and white. Each of these color marked Laa illaaha illaa Allah Muhammad Messenger of God and both have a different meaning. In the context of the history of Liwa and Rayah flag used by the Prophet Muhammad and the cultural context and Rayah Liwa flag is used to establish the Khilafah state. With the legitimacy that the flag is the monotheistic flag of the Ministry of Defense so that the Indonesian Hizb ut-Tahrir organization uses the flag as a manifestation of the Khilafah Islamiyah as an ideology in the government system. Hizbut Tahrir insists that the flag Liwa and Rayah not the flag but the flag of Islam. Semiotic analysis of Ferdinand de Saussure, With semiotikanya theory consisting of four concepts, but in this study the researchers only used two concepts is the first between signifiant and signifie and both concept langue and parole. As the shape of the object flag Hizbut Tahrir and hadith texts about liwa and Rayah become the object of focus in this study.
Quantitative Disorder Analysis and Particle Removal Efficiency of Polypropylene-Based Masks
Authors: Makin R. A. , York K. R. , Messecar A. S. , Durbin S. M. 
Published: September 2020

AbstractWe demonstrate a methodology for predicting particle removal efficiency of polypropylene-based filters used in personal protective equipment, based on quantification of disorder in the context of methyl group orientation as structural motifs in conjunction with an Ising model. The corresponding Bragg-Williams order parameter is extracted through either Raman spectro-scopy or scanning electron microscopy. Temperature-dependent analysis verifies the presence of an order-disorder transition, and the methodology is applied to published data for multiple samples. The result is a method for predicting the particle removal efficiency of filters used in masks based on a material-level property.
Hubungan Antar Agama pada Masa Kerajaan Usmani
Authors: Hakim Lukman 
Published: September 2020

This paper focuses on the concept of religious tolerance in the Ottoman Empire after the conquest of Constantinople by Sultan Muhammad al-Fatih II. This idea had been known as the millet system. The implementation of the millet system under the Ottoman rule was proof that the Ottoman empire had been able to implement religious and cultural harmony. They lived in harmony to make a peace among religions. This paper also attempts to describe a millet system model that had been running for hundreds of years since this concept was created. Co-existence in religious and cultural diversity has been demonstrated by the Ottoman empire in its multicultural and multireligious society. This paper also shows how the millet system can provide benefits if the authorities provide space for recognition to minority groups or people in the territory. Keyword: Non-Muslim, Millet system, Ottoman, communities.
Pelestarian Bahasa-Sastra Sunda oleh Paguyuban Sastrawati Sunda Patrem (1982-2018)
Authors: Ristiana Ika , Syahir Muharam Amung Ahmad 
Published: September 2020

Paguyuban Sastrawati The Sunda Patrem Sastrawati is the organization of Sundanese female authors in West Java that was founded on November 4, 1982. Patrem is a Sundanese woman's hairpin used in ancient times. Patrem was then chosen as the name and symbol for the Sundanese literary organization, as well as linking it to the Patrem used by Princess Dyah Pitaloka in the Bubat War which became a symbol of the beauty and strength of Sundanese women. The special characteristic of the Sunda Patrem Sastrawati Circle of Friends is to use Sundanese as the identity of the organization, and to maintain the customs and beliefs of the Sundanese people as Sundanese identity, so the writer is interested in studying the role played by the Sunda Patrem Circle. The purpose of this study is to reveal the role of Sundanese women as writers who contribute in realizing the development of the Indonesian Nation. This research was conducted using the Historical Research Methods (Heuristics, Criticism, Interpretation, and Historiography) with a social and cultural science approach. The Sastrawati Sunda Patrem Circle through its work program has helped the success of the Indonesian government and community program in National Development in the Regional Culture, especially the Sunda Region.
Rufaidah Al-Aslamiyah: Perawat Pertama di Dunia Islam (Abad 6-7 M.)
Authors: Saputra Abdul Hamid , Kusdiana Ading , Rahmatillah Tolib 
Published: September 2020

The practice of Islamic health emerged in the sixth century AD influenced by three health traditions, namely ancient civilization, Bedouin Arabic, and Thibbun Nabawi. There is no much data related to health practice around the sixth century to the seventh century BC, except for nursing conducted by Rufaidah Al-Aslamiyah. She became an important figure in developing Islamic health practice and the involvement of women in the Islamic war. The purpose of this research is to determine the description of medicine/health in the Islamic world in the classical period and the role of Rufaidah Al-Aslamiyah in her involvement nursing field of the Islamic world. The method of this research is the historical research. The research method was carried out through four-stage, they are heuristics, criticism, interpretation, and historiography. Based on the research conducted, it could be stated that the practice of world health has emerged since 7,000 BC. In the sixth to seventh centuries Rufaidah Al-Aslamiyah had an important role in the development of world health practice. She started nursing for the first time in the Islamic world. Some of her important roles include: establishing a nursing school, participating in the war, establishing a field hospital, creating a nurse code of ethics, developing Islamic spiritual services, and being active in social activities in the city of Medina. It has also been proven that the first nursing knowledge was not conceived by Florence Nightingale in the 19th century, however, it has existed since the sixth century by Rufaidah Al-Aslamiyah. Keywords: Health practice, Islamic health practice, nursing.
Undang-Undang Sumatera Barat (Minangkabau) Tahun 1837-1862
Authors: Yulianti Yulianti , Syahir Muharam Amung Ahmad , Lestari Fathia 
Published: September 2020

This article discusses the constitution (undang-undang) of West Sumatra. The Minangkabau people constitute the Matrilineal community. Their customs and culture place the women as the inheritors of inheritance and kinship. Nevertheless, the role of men who actively play roles in religious and political spheres is still significant. Seen from their economy, the Minangkabau indigenous people have a wealth of fertile land so that the majority of the community's work is farming various plants such as coffee, spices, rice etc. The progress of the community is not only in the economic field but also the development of Islam. The spread of Islam continues to grow and the Islam has been a popular religion among the Minangkabau people. The community also has a legal order written in an Act, which was written in Minangkabau in 1837 precisely after the Padri war and the Dutch rule in the Minangkabau land. Dutch Residents (Heinmers) ordered community leaders to write a customary law into the West Sumatra Act, the enactment of this West Sumatra Law until 1862 because when the Dutch set new regulations on the Minangkabau community, namely stelsel culture so that people followed all the new rules. The West Sumatra Law is divided into three parts: the Adat Law in Nagari, the Murder Case Law, and the Syara Companding Adat Law. Keywords: Minangkabau Society, customary law, local act.
Sejarah PLTA Lamajan Pangalengan Sebagai Situs Peninggalan Belanda di Kabupaten Bandung Tahun 1925
Authors: Kholis Sofiah Asri Nur , Hakim Ajid 
Published: September 2020

This study aims to determine how the history of the Lamajan Hydroelectric Power in 1925, both in terms of the geographical, demographic conditions of Pangalengan and also the components that still exist in Lamajan. Lamajan is a Dutch hydroelectric power plant (PLTA) which was built in 1924 in Pangalengan, Bandung and has been operating since 1925. Lamajan has three generator units, the engine used by Lamajan supplied from the Dutch factories Heemaf and Smit Slikkerveer, initiated by V.H Willem Smith & Co. and R.W.H. Hofstede Crull. The method used in this study is a qualitative method, namely by collecting data through literature and documentation. This method is carried out through four stages namely, heuristics, criticism, interpretation, and historiography. The results of this study show this hydroelectric power plant was built during the Dutch colonial era in 1920-1924 and operated in 1925. This power plant was initially built by a Dutch engineer named Willem Beyerinc K. for the electricity needs of sugar factories but over time was used to illuminate the area of Bandung and its surroundings, this power plant utilizes the flow of water from the Cisarua and Cisangkuy rivers.
Genre Baru Kasidah Sufistik di Indonesia 2001-2010
Authors: Fauziyyah Ai Shidqi Farchah , Mardani Mardani 
Published: September 2020

The process of Islamization has caused acculturation among the Nusantara and foreign culture. One of them is in the field of music, namely “Kasidah”. Initially the kasidah only used a tambourine instrument (rebana), later in its development it was mixed with Western musical instruments (guitar, bass, keyboard and drums), its name became the modern kasidah. Along with the development of the times, the Kasidah also went through a process of deculturation. Where the kasidah is no longer unique to the rebana, musicians in Indonesia have left the tambourine and only use modern musical instruments. a new genre emerged in kasidah, namely pop kasidah. This study uses historical research methods, namely research models that study past events based on the traces they have left. This research method is carried out in four stages, namely heuristics, criticism, interpretation and historiography. In 2001, a Sufi Muslim music group was born with personnel from various countries, namely Dust. They use many musical instruments from various countries as well, this is what causes the music color of Dust to be different from the others.
Design and Analysis of 7-DOF Human-Link Manipulator Based on Hybrid Intelligent Controller
Authors: Al Mashhadany Yousif 
Published: September 2020

A manipulator is an alternative to progress profitability in mechanical computerization. The robotic controller executes forms’ assembly operations in hazardous conditions. Since computerized controllers are highly vulnerable nonlinear powerful frameworks, it is hard to provide precise unique conditions at controlling laws’ configuration. Virtual Reality (VR) is a fundamental advance at use in modern biomedical, medical procedures and different fields where a 3D object helps to comprehend complex behavior. This work proposes the interaction with 3D models in VR environment achieved by accurate sensing from feedback, and then reconstructs the instruction according to practical limitation of a real human arm movement.
In this work ANFIS played a key role in finding results with optimal values because the combination of Neural Networks (NN) benefits and obscure logic systems research examined the individual defects in both of them. Use of Artificial Neural Networks (ANN) in dynamic systems has quite extensive and accurate results, when adding a training signal system to the mixed learning base implemented at combining the slope proportions technique, a Least Square Error (LSE) preparing the ANFIS organization for any framework to take care of the issue any way. This work presents a keen controller actualization with 7-DOF controller for a model designed with a VR situation that reproduces the system design by associating Matlab/Simulink to connect the VR model with some instruction to execute orders delivered by the hybrid intelligent controller based on ANFIS technique. Palatable outcomes are implemented in reproductions that improve the procedure as an essential utilization of this controller design.