bluuebunny/crossref_metadata_2025_split huggingface dataset:
STUDY OF THE INFLUENCE OF CRACKS ON THE BEARING CAPACITY OF REINFORCED CONCRETE PLATES USING THE PRINS CALCULATION COMPLEX
Authors: Aydemirov K. R. , Agapov V. P. 
Published: January 2020

Objectives. In order to determine a residual safety factor, a finite element method is considered for determining the bearing capacity of reinforced concrete plates having defects in the form of cracks.Method. The methodology is based on the use of structural calculation algorithms that take physical nonlinearity implemented in the PRINS programme into account. These algorithms assume the use of the same computational scheme in the process of solving the problem. However, the specificity of the task consists in considering differences between the calculation schemes of the initial structure and the structure having cracks.Result. With this in mind, the algorithms of nonlinear structural analysis according to the PRINS programme are supplemented with an option that allows the parameters of the design scheme to be changed in an end-to-end calculation process. Multilayer finite elements are used to study the load-bearing capacity of reinforced concrete plates, each having a specific material package. The modernisation of the design scheme in this case consists in replacing one package of materials with another. The input file of the PRINS programme is supplemented by a description of cracks with an indication of their location and all other relevant characteristics. Examples of problems arising when determining the bearing capacity of a plate with defects in the form of cracks under various boundary conditions are given.Conclusion. The problem of determining the bearing capacity of reinforced concrete plates with defects in the form of cracks can be effectively solved using a reconfigurable design scheme for end-to-end calculation. In the event of defects appearing in the form of cracks, this will enable operational services to monitor changes in the bearing capacity of buildings and structures containing reinforced concrete plates, as well as to determine the operability of structures and make substantiated decisions in case of repair.
MODERNISED DESIGN OF A HYDROSTATIC DENSIMETER FOR MEASURING DENSITY OF HIGHLY VISCOUS OILS
Authors: Sagdeev D. I. , Abdulagatov I. M. , Nikulin N. K. , Tyulkin V. I. 
Published: January 2020

Objectives. The aim of this work is to modernise a VT-KHTI densimeter operated by the method of hydrostatic weighing in order to study the density of highly viscous oils and oil products in the temperature range from 293 K to 473 K at atmospheric pressure.Method. Among the many methods for studying density, the following were used in the course of the study: the constant- and variable-volume piezometer method and the method of hydrostatic weighing.Results. The results of the densimetric study of highly viscous oils obtained from the Republic of Tatarstan in the temperature range from 293 K to 473 K at atmospheric pressure. The following grades are presented: Ashalchinskaya oil (super-viscous, SVO); Kuakbash oil (sulphur), Kichuy oil and Devon oil. Following an analysis and selection of methods for measuring density, a technique for error estimation and densimeter calibration is presented. A calculated expression for the hydrostatic weighing method, derived from the modernised hydrostatic densimeter design for measuring the density of highly viscous oils, is presented.Conclusion. The VT-KHTI densimeter for vacuum working fluids has been modernised and calibrated for research work on measuring the dynamic viscosity coefficient of both Newtonian and non-Newtonian liquids.
Toward Standardized Monitoring of Patients With Chronic Diseases in Primary Care Using Electronic Medical Records: Development of a Tool by Adapted Delphi Procedure
Authors: Falck Leandra , Zoller Marco , Rosemann Thomas , Martínez-González Nahara Anani , Chmiel Corinne 
Published: January 2020

Background
Long-term care for patients with chronic diseases poses a huge challenge in primary care. There are deficits in care, especially regarding monitoring and creating structured follow-ups. Appropriate electronic medical records (EMR) could support this, but so far, no generic evidence-based template exists.

Objective
The aim of this study is to develop an evidence-based standardized, generic template that improves the monitoring of patients with chronic conditions in primary care by means of an EMR.

Methods
We used an adapted Delphi procedure to evaluate a structured set of evidence-based monitoring indicators for 5 highly prevalent chronic diseases (ie, diabetes mellitus type 2, asthma, arterial hypertension, chronic heart failure, and osteoarthritis). We assessed the indicators’ utility in practice and summarized them into a user-friendly layout.

Results
This multistep procedure resulted in a monitoring tool consisting of condensed sets of indicators, which were divided into sublayers to maximize ergonomics. A cockpit serves as an overview of fixed goals and a set of procedures to facilitate disease management. An additional tab contains information on nondisease-specific indicators such as allergies and vital signs.

Conclusions
Our generic template systematically integrates the existing scientific evidence for the standardized long-term monitoring of chronic conditions. It contains a user-friendly and clinically sensible layout. This template can improve the care for patients with chronic diseases when using EMRs in primary care.
CO-CRYSTALS OF CARVEDILOL: PREPARATION, CHARACTERIZATION AND EVALUATION
Authors: THENGE RAJU , PATEL RAKESH , KAYANDE NANDU , MAHAJAN NILESH 
Published: January 2020

Carvedilol an antihypertensive drug, exhibit poor solubility and dissolution rate. Hence an attempt has been made to prepare the Co-crystals of Carvedilol to increase the solubility and dissolution rate by solvent evaporation method using coformer such as succinic acid, fumaric acid and oxalic acid. The prepared Co-crystals were evaluated for solubility, dissolution rate and micromeritic properties. The Co-crystals were characterized by scanning electronic Microscopy (SEM), FT-Infrared Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC) and X-ray Diffractometry (XRD). The CAR-SA Co-crystal, CAR-FA Co-crystals and CAR-OA Co-crystals showed increased in solubility and dissolution rate compared to pure Carvedilol. The Co-crystals formed with coformer have showed improved micromeritic properties. SEM clearly showed the formation of new solid phase with the coformer. The FT-IR spectra indicate the shifting of characteristic peak in the Co-crystals but does not showed any interaction between the coformer used. DSC data showed the change in the endotherm with the melting points of Co-crystals. XRD spectra indicate the notified difference in the 2θ and the intensity of the peaks. Hence the Co-crystal formation could be helpful to improve the solubility, dissolution and micromeritic properties of Carvedilol.
DEVELOPMENT OF ORALLY DISINTEGRATING TABLETS OF MEMANTINE HYDROCHLORIDE-A REMEDY FOR ALZHEIMER’S DISEASE
Authors: GHOGARI IMRAN S. , JAIN PRITAM S. 
Published: January 2020

Objective: The study is directed towards the development of an orally disintegrating drug delivery system of memantine hydrochloride which can be commercially exploited for the well-being of society for the treatment of Alzheimer’s disease, which is a most common form of dementia.
Methods: Orally disintegrating immediate-release tablets of memantine hydrochloride were prepared and optimized for disintegration time and in vitro drug release. The top spray granulation method was used for the preparation of granules. Subsequently, these granules were compressed to tablets. The levels of diluent, disintegrant and taste-masking agents were optimized using the design of experiments. The resulting tablets were evaluated for disintegration time and in vitro drug release. The optimized formulation was subjected to accelerated stability study for 3 mo.
Results: The optimized orally disintegrating tablet formulation exhibited a disintegration time of 2-3 min and complete drug release i.e. more than 85 % drug release within 10 min while performing in vitro drug release study. This is a prerequisite for faster action in the case of patients suffering from Alzheimer’s disease. Accelerated stability studies indicated good physical and chemical stability of the optimized formulation.
Conclusion: Developed orally disintegrating tablet formulation of memantine hydrochloride could release the drug faster compared to conventional immediate-release tablets which is useful in paediatric, geriatric and psychiatric patients.
Pendidikan Kesehatan Tentang Deteksi Dini Kanker Payudara Melalui Pemeriksaan Sadari (Periksa Payudara Sendiri) Di Pondok Pesantren Al-Hidayah dan Al- Maarif Kota Jambi
Authors: Yusnilawati Ns , Mawarti Ns. Indah , Rudini Dini 
Published: January 2020

Abstrak: Kematian akibat kanker payudara dapat mengalami penurunan dengan dilakukannya deteksi dini terutama pada usia remaja dengan melakukan pemeriksaan payudara sendiri. Tindakan ini sangat penting karena hampir 85% benjolan di payudara ditemukan oleh penderita sendiri. Pemeriksaan payudara sendiri (SADARI) dapat memperkecil angka kematian sampai 20%, namun jumlah perempuan yang melakukan SADARI masih sedikit yaitu 25-30%. Riset Penyakit Tidak Menular (PTM) tahun 2016 menyatakan perilaku masyarakat dalam deteksi dini kanker payudara masih rendah. Tercatat 53,7% masyarakat tidak pernah melakukan SADARI, sementara 46,3% pernah melakukan SADARI; dan 95,6% masyarakat tidak pernah melakukan SADANIS, sementara 4,4% pernah melakukan SADANIS. Hal ini dilatarbelakangi oleh banyak nya remaja Indonesia yang belum mengetahui dan menyadari pentingnya SADARI untuk deteksi dini kanker payudara.
Metode : Mengikuti sosialisasi mengenai pentingnya deteksi dini kanker payudara melalui pemeriksaan “SADARI”(periksa payudara sendiri).Mengumpulkan para santriwati yang menjadi peserta pendidikan kesehatan. Mempersiapkan sarana dan prasarana kegiatan pendidikan kesehatan deteksi dini kanker payudara melalui pemeriksaan “SADARI”(periksa payudara sendiri), Mempersiapkan evaluasi dan monitoring secara bersama
Hasil : jumlah peserta di pondok pesantren Mambaul ulum lebih banyak dibandingkan Pesantren Al Maarif yaitu di pondok pesantren Mambaul Ulum sebanyak 125 orang (80 %) dan responden di Pondok Pesantren Al Maarif sebanyak 25 orang (20 %).Pendidikan kesehatan tentang deteksi dini kanker payudara melalui SADARI ini disampaikan oleh pihak puskesmas talang bakung yang menjadi wilayah kerja bagi lingkungan Pondok Pesantren. Setelah diberikan penyuluhan kemudian setiap peserta diberikan leafleat selaku responden yang berisikan materi tentang SADARI.
Kesimpulan: Penyuluhan kesehatan adalah salah satu bentuk promosi kesehatan yang sederhana dan dapat mencakup sasaran yang luas. Dari hasil penyuluhan kesehatan tentang “Deteksi dini kanker payudara melalui SADARI (Periksa payudara sendiri) yang telah dilakukan, dapat diambil kesimpulan bahwa siswi – siswi Pondok pesantren Mambaul Ulum dan Al Maarif dapat mengetahui tentang pentingnya pemeriksaan SADARI untuk deteksi dini kelainan pada payudara dan mencegah terjadinya kanker payudara serta bagaimana melakukan SADARI itu sendiri.
ANALISIS LOYALITAS KONSUMEN PRODUK BERLABEL HALAL
Authors: Izzah Lubis Nurul 
Published: January 2020

This article aims to determine how much is the influence the product quality, brand image and halal label to consumer loyalty product of PT. Unilever Indonesia. The research method used is quantitative approach with multiple linear regression analysis. The research used primer and secondary data from consumer product of PT. Unilever Indonesia in Desa Hutaraja. The result of the research showed that there was the positif influence of product quality and brand image variable to the consumer loyalty product of PT. Unilever Indonesia in Desa Hutaraja. The result of the research also showed that there was not influence of halal label variable to the consumer loyalty product of PT. Unilever Indonesia in Desa Hutaraja.
Effects of participating in the annual Animal Welfare Assessment Contest on veterinary students' self-perceived knowledge of and attitudes toward animal welfare science and their career choices
Authors: Johnson Cia L. , McKinney Lindsey J. , Patterson-Kane Emily G. 
Published: January 2020

Abstract

OBJECTIVE
To evaluate the impact of participating in the annual Animal Welfare Assessment Contest (AWJAC) on veterinary students' self-perceived knowledge of and attitudes toward animal welfare science and on participants' career choices.

SAMPLE
46 veterinary students who participated in the AWJAC from 2014 through 2017.

PROCEDURES
The study consisted of 2 parts. In part 1, a survey regarding participation in the AWJAC was emailed to all 138 veterinary students who participated in the contest from 2014 through 2017. In part 2, a self-selected subset of 4 survey respondents were interviewed by telephone regarding their AWJAC experience.

RESULTS
Forty-six of 138 (33%) AWJAC participants responded to the online survey. When respondents were asked to rate the attitudes they held before and after participating in the AWJAC, significant increases were identified for engaging with animal welfare topics in their professional decision-making, making career choices based on their interest in animal welfare, and having their interest in animal welfare shape their professional career choices. Analysis of telephone interview transcripts revealed 3 major themes regarding AWJAC participation: defining animal welfare, the value of networking, and professional preparedness.

CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested that participation in the AWJAC heightened veterinary students' self-perceived awareness of animal welfare science, provided participants an opportunity to expand their professional networks, and prepared participants for entrance into the veterinary profession by enhancing communication and critical thinking skills.
Pengukuran Sumbatan Hidung pada Deviasi Septum Nasi
Authors: Budiman Bestari J , Asyari Ade 
Published: January 2020

Abstrak
Latar Belakang: Gejala sumbatan hidung meskipun bukan suatu gejala penyakit yang berat, tetapi dapat
menurunkan kualitas hidup dan aktivitas penderita. Penyebab sumbatan hidung dapat bervariasi dari berbagai
penyakit dan kelainan anatomis. Salah satu penyebab dari kelainan anatomi adalah deviasi septum nasi. Tujuan:
Untuk menilai gejala dan derajat sumbatan hidung pada deviasi septum nasi. Tinjauan Pustaka: Diagnosis dari
gejala sumbatan hidung sangat kompleks dan bervariasi, selain berdasarkan anamnesis dan pemeriksaan fisik
juga diperlukan pemeriksaan penunjang untuk pengukuran sumbatan hidung. Skor sumbatan hidung merupakan
salah satu parameter untuk menilai suatu sumbatan hidung pada deviasi septum nasi. Untuk itu diperlukan
pemeriksaan penunjang yang dapat digunakan untuk mendiagnosis dan mengevaluasi gejala sumbatan hidung,
diantaranya adalah nasal inspiratory flow meter, rhinomanometri dan rhinometri akustik. Kesimpulan: Gejala
sumbatan hidung pada deviasi septum dapat dievaluasi dengan pemeriksaan tambahan meliputi pemeriksaan
dengan spatula lidah, nasal inspiratory flow metry, nasal expiratory flow metry, rinomanometri, dan rinometri
akustik.
Kata kunci: sumbatan hidung, deviasi septum, nasal inspiratory flow metry, nasal expiratory flow metry,
rinomanometri, rinometri akuistik.
Abstract
Background: Although nasal obstruction is not a severe symptom of the disease, it can decrease the quality
of life and activity of the patient. The etiology of nasal obstruction could be varied from any diseases and
anatomical abnormalities. One of anatomical abnormality cause is septal deviation. Purpose: To evaluate the
symptom and the degree of nasal obstruction in septal deviation. Review: The diagnosis of nasal obstruction is
more complex and varied, based on anamnesis and physical examination, and beside that need additional
examination to measure the nasal patency. Nasal obstruction score is one of parameter to evaluate the obstruction
of nose. Because of that, it needs additional examination to diagnose and evaluate the nasal obstruction, include
nasal inspiratory flow meter, rhinomanometry, acoustic rhinometry. Conclusion: Nasal obstruction in septal
deviation with additional examination, such as tongue spatula, nsal expiratory flow metry, nasal inspiratory flow
meter, rhinomanometry, acoustic rhinometry.
Keywords: Nasal obstruction, septal deviation, nasal inspiratory flow meter, nasal expiratory flow metry,
rhinomanometry, acoustic rhinometry
Molecular activities in Moringa oleifera Linn - Review
Authors: Sridevi Subramonie  , Nagaraja Suryadevara  , Balavinayagamani Ganapathy  , Gokila Devi T  
Published: January 2020

The terrific increase by the word "modernization" in various fields in the world without boundaries affects the total environmental system, which leads to the emergence of various new diseases in various forms. In that case, cancer is considered as one of such a dreadful disease which is also measured as a leading cause for the death of the people. Even with the advanced treatment of modern medicine in treating cancer and reduce the rate of cancer recurrence using advanced technologies such as immunotherapy, targeted therapy, robotic radiosurgery are still very subjective to the individual, and it causes tremendous side effects to the patient. Alternative medicine plays a vital role in the treatment and management of diseases event before centuries. Many pharmaceutical companies involved in the research development of anticancer properties as a holistic approach in the treatment and management of cancer. Moringa oleifera, traditionally used as food sources, has attracted many researches to evaluate the biochemical properties of medicinal and antioxidant as an antiulcer, antimicrobial, antitumour and anticancer. Each part of the tree is nutritive and personalized selective on phytochemicals as an anticancer drug are essential in treating the cancer cells. Limited knowledge on the cytotoxic activity and therapeutic index of M. oleifera in treating specific types of cancers are still under study by many researchers. However, the molecular analysis of anticancer properties in Moringa oleifera as sustainable preventive and management of cancer therapy still lacking in Malaysia
¿Son los tapones auditivos eficaces para prevenir los efectos de la contaminación auditiva mediante la atenuación sonora?
Authors: Coello Fausto , Males Diego , Tello Denisse , López -Pulles Ramiro 
Published: January 2020

Contexto: los efectos de la exposición a la contaminación sonora incluyen síntomas auditivos como hipoacusia, elevación del umbral auditivo, trauma acústico y también no auditivos de tipo psicológico, físico y social.Material y métodos: estudio descriptivo analítico y transversal para determinar la eficacia de la atenuación sonora de los protectores auditivos personalizados en un grupo de 33 pacientes hombres sin alteraciones físicas del conducto auditivo externo, mediante la comparación de las respuestas obtenidas en el oídoreal libre y sin amplificación (Real-Ear Unaided Response) y con el oído herméticamente ocluido por medio de un tapón de silicona hecho a la medida (Real-Ear Occluded), ante la presencia de un ruido externo estable de banda ancha de 65 dB de intensidad, utilizando para ello un equipo de precisión certificado connormas ISO (Verifit de Audioscan).Resultados: se encontró que existe mayor protección a los decibeles altos con las frecuencias: 2000 Hz, 3000 Hz y 4000 Hz, bajando de 65 a 40 decibeles que traduce una reducción del 61%; no existe diferencia significativa entre ambos oídos, lo cual se explica por las particularidades en las formas anatómicas, profundidad de la inserción y la adecuada colocación de la sonda microfónica. Los valores promedio de atenuación bilateral en dB SPL que se logra en las diferentes frecuencias con tapones personalizados de protección auditiva varían dependiendo de la misma, con 250 Hz es de 9,97 en el oído derecho y 9,36 en el oído izquierdo y con 6000 Hz 15,28 en el oído derecho y 13,64 en el oído izquierdo. Una mayor atenuación se encontró con 3000 Hz (OD: 32,11 OI: 30,69), 2000 Hz (OD: 28,33 OI: 28,47) y 4000 Hz (OD: 27,28 OI: 26,67). Conclusión: el uso de protectores auditivo logra una evidente reducción de los niveles sonoros, sobre todo con frecuencias agudas (primeras) cuyos umbrales se afectan al someterse a elevados niveles de ruido por tiempos prolongados.
Peningkatan Kompetensi Guru Biologi Melalui Pendampingan Kegiatan Pembelajaran Berbasis Lesson Study di SMAN 1 Lembar
Authors: Jamaluddin Jamaluddin , Jufri A Wahab , Ramdani Agus , Azizah Afriana 
Published: January 2020

Tujuan kegiatan pengabdian pada masyarakat ini adalah untuk, 1) meningkatkan kualitas perencanaan pembelajaran biologi (penyusunan perangkat pembelajaran) dengan menerapkan pola lesson study di SMA Negeri 1 Lembar, 2) meningkatkan kualitas proses pembelajaran biologi dengan menerapkan pola lesson study di SMA Negeri 1 Lembar, dan 3) meningkatkan kualitas cara mengevaluasi pembelajaran dengan menerapkan pola lesson study di SMA Negeri 1 Lembar. Manfaat yang dapat diperoleh melalui kegiatan pengabdian pada masyarakat ini antara lain, 1) secara praksis dapat meningkatkan kualitas pembelajaran biologi melalui penerapan model-model pembelajaran inovatif denganpola lesson studi, 2) dapat mengembangkan kompetensi pedagogik guru khususnya dalam merencanakan, melaksanakan, dan mengevaluasi pembelajaran dengan pola lesson studi, 3) hasil yang akan diperoleh dapat digunakan sebagai acuan dalam merencanakan, melaksanakan, dan mengevalusai pembelajaran biologi dengan pola lesson studi. Kegiatan pengabdian pada masyarakat ini akan dilaksanakan melalui tiga tahap, yaitu 1) sosialisasi dan focus group discussion tentang materi lesson study, 2) pendampingan pembuatan perangkat pembelajaran dengan pola lesson studi, 3) pendampingan pada saat melaksanakan dan mengevaluasi pembelajaran dengan pola lesson studi. Metode yang digunakan dalam kegiatan ini antara lain adalah, 1) diskusi informasi terkait dengan konsep, prosedur, best practice tentang lesson study, 2) praktek langsung penyusunan perangkat pembelajaran, pelaksanaan proses pembelajaran, dan evaluasi pembelajaran dengan pola lesson studi. Hasil yang diharapkan dapat dicapai melalui kegiatan ini sesuai dengan tujuan yang telah direncanakan, yaitu 1) meningkatnya pemahaman pendidik biologi tentang konsep dan prosedur pembelajaran biologi dengan pola lesson studi, 2) meningkatnya keterampilan pedidik biologi dalam merancang dan melaksanakan pembelajan biologi dengan pola lesson studi, dan 3) meningkatnya keterampilan pendidik biologi dalam mengevaluasi pembelajaran yang telah dilakukan dengan pola lesson studi.Kata Kunci: Kompetensi Pendidik Biologi; Kegiatan Pembelajaran; Lesson Study.