bluuebunny/crossref_metadata_2025_split huggingface dataset:
PROYECTOS DE DESARROLLO TURÍSTICO Y CONSULTA PREVIA: EL CASO DEL PUEBLO RAIZAL EN COLOMBIA
Authors: Morón Castañeda Silvia 
Published: March 2020

Los proyectos de desarrollo turístico se han convertido en uno de los principales motores del progreso económico de países como Colombia, lo cual llama la atención de inversionistas interesados en invertir en determinadas zonas por su riqueza natural y cultural. A raíz de esto, se han generado múltiples conflictos socio ambientales debido a los permisos, autorizaciones y licencias ambientales que las autoridades nacionales han otorgado para el desarrollo de dichos emprendimientos. Sumado a lo anterior, no ha sido valorado adecuadamente el derecho a consultar previamente a los miembros de grupos étnicos protegidos por el Estado y a la participación de estos en la toma de decisiones. La Corte Constitucional de Colombia mediante Sentencia T-800 de 2014, decidió un caso emblemático del pueblo raizal asentado en el municipio insular de Providencia y Santa Catalina del Departamento Archipiélago de San Andrés, Providencia y Santa Catalina, el cual solicitó el amparo de su derecho fundamental a la consulta previa por la realización del proyecto turístico "Spa Providencia".
Mortalidade por suicídio no Espírito Santo, Brasil: uma análise do período de 2012 a 2016
Authors: Tavares Fabio Lucio , Borgo Vinicius Marti Pedroni , Leite Franciele Marabotti Costa , Cupertino Edleusa Gomes Ferreira , Pereira Jacira Dos Anjos , Alves Rodrigo Nascimento Ribeiro , Rosa Mauro 
Published: March 2020

Objetivo: descrever a mortalidade dos óbitos por lesões autoprovocadas intencionalmente no Espírito Santo, Brasil.Materiais e métodos: estudo epidemiológico, baseado em dados secundários sobre a tendência dos suicídios ocorridos no Espírito Santo no período de 2012 a 2016.Resultados: a análise de tendência indicou crescimento da taxa de mortalidade por suicídio ao longo do período de 2012 a 2016 (R2 = 0,9307; p < 0,001). A maioria das vítimas foram homens (73,5 %), pardos (47,9 %), adultos (81,4 %)que morreram por enforcamento, seguido de envenenamento e arma de fogo. O enforcamento foi mais prevalente entre os homens (P = 63; p < 0,001); entre as mulheres, o envenenamento (P = 20,8 %; p < 0,001) e a precipitação de lugar elevado (P = 14 %; p < 0,001).Conclusão: o aumento na mortalidade por suicídio entre a população estudada vem acompanhando a tendência de crescimento no Brasil e no mundo. Acredita-se que este estudo se constitui como mais um recurso de acesso à informação sobre o suicídio de modo a facilitar a tomada de decisão por parte dos órgãos competentes no enfrentamento dessa problemática bem como estimular e ampliar a discussão sobre o tema.
Intern Designed Modules for Conducting Potential Microgravity Solidification Experiments aboard the International Space Station
Authors: McElderry Justin 
Published: March 2020

MMaJIC (Microgravity Materials Joining Investigation Chamber) is a modular experiment chamber for performing materials science investigations. MMaJIC provides a controlled and sealed test environment for a wide variety of soldering and brazing experiment to examine porosity in microgravity. MMaJIC’s modular cartridge design includes a tray for housing the solder experiments and demonstrates simplicity to astronauts. SoLIDD (Solid Liquid Interface Directional Device) is a device for conducting directional solidification experiments which enables control of the microstructural development. SoLIDD has capability for varying temperature gradient and growth velocity. These quantities utilize heaters, coolers, and a directional drive unit. ICED-T (Interface Control Experiment with Directional Translation) is an apparatus that conducts directional solidification experiments of transparent materials which allows direct observation of the solid/liquid interface. Currently, it is in a breadboard phase that consists of the components mounted to a surface that allows the sample to be placed in an upright position. Orientation of the experiment (solid on the bottom, liquid on top) is important during testing ground samples to maintain stability. Ultimately, the goal of ICED-T is to conduct successful ground tests and then be configured to fit into an enclosure similar to MMaJIC and SoLIDD that could be utilized aboard the ISS.
Design of a Robot for the 2019 NASA Robotic Mining Competition
Authors: Braccio Matthew 
Published: March 2020

The viability of extracting water on both the Moon and Mars is a focus of NASA as they explore the idea of In-Situ Resource Utilization (ISRU). Marquette Aerospace and Robotic Systems (MARS) is participating in the 2019 NASA Robotic Mining Competition (RMC), a competition driven by using the systems engineering process to design, build, and test a robot capable of autonomously mining icy-regolith simulant in an off-world terrain to simulate an ISRU mining mission. The team used systems engineering to guide technical management, design, and operations of the robot. With feedback from the team’s faculty advisor and industry sponsors, the team utilized multiple systems engineering approaches. No single systems engineering process was selected, rather the team drew from multiple reference texts. The proposed design satisfies the requirements outlined in the 2019 NASA RMC Rules and Rubrics and placed 6th out of 50 in the competition.
Calibration and Beam-Mapping Techniques for the Tianlai Pathfinder Dish Array
Authors: Oxholm Trevor 
Published: March 2020

Hydrogen intensity mapping is a promising technique to measuring large-scale structure. By detecting the integrated emission of the 21cm HI signal from many galaxies simultaneously, astronomers can survey larger volumes of the universe than ever before. However, systematics related to foreground subtraction, variable antenna beam patterns, and calibration must be overcome before maps can be made of the 21cm signal. The Tianlai Pathfinder array, a first-generation hydrogen intensity mapping experiment, is being constructed in order to practice and demonstrate our ability to overcome these challenges. We demonstrate two methods, delay-delay rate filtering and point source calibration, in order to understand the systematics of the Tianlai instrument. The methods used here will be used to help demonstrate the feasibility of full-scale hydrogen intensity mapping experiments, while contributing to the experimental toolset used for such experiments.
CORPORATE FINANCIAL POLICY AND ITS IMPACT ON SUSTAINABLE CAPITAL STRUCTURE: EMPIRICAL EVIDENCE FROM TEXTILE FIRMS OF PAKISTAN
Authors: Sultan Khurram , Rzgar Ahmed Ramyar , Jafar Rahim , Muzammal Murtaza Muhammad , Gardi Bayar 
Published: March 2020

Purpose of the study: In this article, the objective is to discover the influence of business financial policy on the firm’s Capital structure of the textile zone of Pakistan. The present outcomes of productivity, total assets, future growth, and asset structure have started a discussion over the total debt ratio.
Methodology: The methodology used to conduct this work in order to examine the effect of total assets, future growth, profitability, and asset structure and its impact on total debt ratio, Panel data analysis has been accomplished and together the firm and industry explicit dynamics have been measured, yearly data has been taken off 96 textile firms of Pakistan concluded the period of 2012 - 2017 for OLS, regression model & LSDVM.
Main Findings: The results reveal that the OLS regression model is not a good fit and the model shows that there is no significant impact of all the independent variables on the dependent variables. Whereas the results of LSDVM indicated that this model is a good fit, the model revealed that the entire individuals have combined effect on the dependent variable. Similarly, the alternate hypothesis indicates the significant influence of independent variables on the dependent variable whereas the Null hypothesis indicated no or insignificant influence of independent variables on the dependent variable.
Application of this study: This study contributes toward the financial sector for policymakers in order to construct the best capital configuration of the firm. This study also suggests that which element is having more importance while making capital configuration of the firm.
The originality of this study: Capital structure is a crucial issue for entrepreneurs and CEOs of any firm. The number of studies is available related to other industries but fewer studies are available related to the textile firms of Pakistan so this research work provides the technique while making the best capital configuration for textile firms of Pakistan.
Measuring Medication Adherence Among Type 2 Diabetes: An Integrative Review
Authors: Conway Cheryl , Kelechi Teresa , Gregoski Mathew 
Published: March 2020

Background and PurposeThe literature indicates there is a lack of evidence of a standard for diabetes medication adherence (MA) measures. The purpose of this integrative review (IR) was to identify instruments appropriate to measure MA among adults with T2DM.MethodsThe IR was conducted according to Whittemore and Knafl (2005) methodology. The databases CINAHL, OVID, PubMed, and Scopus were searched for manuscripts published between 2006 and 2016 using the keywords “adherence,” “diabetes,” “instrument,” and “measure.” Ten manuscripts reflecting the psychometric properties of twelve published instruments were reviewed.ResultsThe most commonly used instrument was the Morisky Medication Adherence 8 item. Reliability and validity varied among studies.ConclusionThe findings suggest the need for continued psychometric testing of diabetes MA instruments.
Contrarreforma psiquiátrica e o trabalho profissional dos/as assistentes sociais nos Centros de Atenção Psicossocial-CAPS´s em Belém-Pará
Authors: Silva Rosiane Silva da , Gomes Vera Lúcia Batista 
Published: March 2020

Este artigo objetiva analisar as repercussões da contrarreforma psiquiátrica em curso, no Brasil, para o trabalho profissional das/os assistentes sociais que atuam nos CAPS´S em Belém-Pará. Tem por base teve por base, os dados obtidos com a realização de uma pesquisa em nível regional, com recorte para os mencionados CAPS’s, cujos sujeitos forma 09 (nove) assistentes sociais de um universo de 34 (trinta e quatro) que atuam nesses espaços sócio ocupacionais. A luz da teoria marxista, o artigo evidencia que o/a assistente social é chamado de forma mais significativa para compor as equipes multidisciplinares nos serviços substitutivos de saúde mental, para intervir sobre os determinantes sociais do processo saúde-doença mental. Mas, as condições de trabalho nos mencionados CAPS’s, têm dificultado o trabalho desse/a profissional no que concerne ao acesso dos usuários ao atendimento, devido as medidas de retrocesso ao acesso aos direitos sociais, provocados pelo momento político e econômico vivenciado, no País, pois até a infraestrutura física dos CAPS´s limita e, muitas vezes, impede que os atendimentos sejam efetuados com qualidade e preservem a privacidade das/os usuários/as. Desta forma, o Estado neoliberal não investe na qualidade dos serviços públicos prestados precarizando suas estruturas; nos serviços como o CAPS´s esta situação se agrava devido possuir uma demanda com uma carga de sofrimento muito densa – ao se deparar com os entraves no acesso aos serviços prestados na RAPS, em geral.
Modulation of Pharmaceutical and Pharmacokinetic Attributes of Curcumin Encapsulated in Chitosan Using Spray Drying Technique
Authors: Roopa G  , Venkatesh, Jayanthi C  , Hanumanthachar Joshi  
Published: March 2020

The present study is designed to formulate and characterize Curcumin (CUR) loaded Chitosan nanoparticles by ionic cross linking using TPP by employing spray drying technique to enhance the aqueous solubility, hence oral bio availability of Curcumin. Curcumin is very sparingly aqueous soluble, unstable in alkaline conditions and gets eliminated faster, resulting in poor bio availability. Curcumin in alcohol was used as drug loading solution. Tween 80 served as nano emulsifier and stabilizer. EE of optimized formulation F6 was found to be 98.5 ± 0.16 %. This formulation has an average particle size of 25 ± 0.1 nm. The Zeta potential of the formulation is -200 mV. FTIR results revealed the absence of characteristic CUR peak in Curcumin Chitosan nanoparticles implying the successful incorporation of CUR into the Chitosan matrix. DSC thermograms witnessed that the crystalline form of CUR is transformed into amorphous form, having better dissolution and stability profile. SEM imaging of the nanosuspension formulation showed the topological features of the prepared nanoparticles. The nanoparticles were more spherical, discrete and homogeneous. % cumulative drug release studies exhibited very less drug release in Simulated Gastric Fluid (SGF- 3.97 %) and Simulated Intestinal Fluid (SIF - 4.2 %) exhibiting sustained release. Pure Curcumin showed burst release of approximately 95 % in 2 h in SGF with a decline in the concentration after 2 h in SIF due to significantly increased degradation in the alkaline conditions. The oral bioavailability (AUC) of Curcumin in female wistar rats increased 11-times following ingestion of Curcumin nanosuspension in comparison with conventional Curcumin suspension. The maximum concentration Cmax of 1034 ± 96 ng / ml for nanosuspension and 94 ± 9.4 ng / ml for Curcumin suspension and was observed at tmax of 2 h for both nanosuspension and suspension.
GWAS and co-expression network combination uncovers multigenes with close linkage effects on oleic acid content accumulation in Brassica napus
Authors: Qian Lunwen , Yao Min , Guan Mei , Zhang Zhenqian , Cui Yixin , Chen Hao , Jan Habib U. , Voss-Fels Kai P. , Werner Christian R. , He Xin , Guan Chunyun , Snowdon Rod J. , Hua Wei 
Published: March 2020

Abstract

Background: Strong artificial and natural selection causes the formation of highly conserved haplotypes that harbor agronomically important genes. GWAS combination with haplotype analysis has evolved as an effective method to dissect the genetic architecture of complex traits in crop species. Results: We use the 60K Brassica Infinium SNP array to perform a genome-wide analysis of haplotype blocks associated with oleic acid (C18:1) in rapeseed. Six haplotype regions were identified as significantly associated with oleic acid (C18:1) that mapped to chromosomes A02, A07, A08, C01, C02, and C03. Additionally, whole-genome sequencing of 50 rapeseed accessions revealed three genes ( BnmtACP2-A02 , BnABCI13-A02 and BnECI1-A02 ) in the A02 chromosome haplotype region and two genes ( BnFAD8-C02 and BnSDP1-C02 ) in the C02 chromosome haplotype region that were closely linked to oleic acid content phenotypic variation. Moreover, the co-expression network analysis uncovered candidate genes from these two different haplotype regions with potential regulatory interrelationships with oleic acid content accumulation. Conclusions: Our results suggest that several candidate genes are closely linked, which provides us with an opportunity to develop functional haplotype markers for the improvement of the oleic acid content in rapeseed.
The initiation of a neuraxial analgesia service on the rate of cesarean delivery in Hubei, China. a 1-year restrospective studyThe initiation of a neuraxial analgesia service on the rate of cesarean delivery in Hubei, China. a 1-year restrospective study
Authors: ZHAO Yun , GAO YING , SUN Guoqiang , YU Lin , LIN Ying 
Published: March 2020

Abstract
Background No Pain Labor ＆Delivery (NPLD) is a nongovernmental project to increase access to safe neuraxial analgesia through specialized training. This study explores the change is overall cesarean delivery (CD) and maternal request CD(MRCD) rate in our hospital after the initiation of neuraxial analgesia service. Methods The neuraxial labor analgesia（NA） was initiated in May 1st 2015 by the help of NPLD. Since then, the application of NA became a routine operation in our hospital, and every parturient can choose to use NA or not according to her own requirement. The monthly rates of NA, CD, MRCD, multiparous women, intrapartum CD, episiotomy, postpartum hemorrhage (PPH), operative vaginal delivery and neonatal asphyxia of vaginal delivery were analyzed from May 1st 2015 to April 30th 2016. Results The rate of NA in our hospital was getting increasingly higher from 26.1% in May 2015 to 44.6% in April 2016 (p<0.001); the rate of CD was decreased from 50.4% in May 2015 to 36.3% in April 2016 ( p<0.001); the rate of MRCD was decreased from 10.8% in May 2015 to 5.7% in April 2016 (p<0.001), but the rate of multiparous women had no change (p＞0.05). There was a negative correlation between the rate of NA and that of overall CD, r=-0.803 (95%CI[-0.951, -0.642], p=0.002), and also a negative correlation between the utilization rate of NA and that of MRCD, r=-0.790 (95%CI[-0.971, -0.497], p=0.004). The rates of episiotomy, PPH, operative vaginal delivery and neonatal asphyxia in women underwent vaginal delivery as well as the rates of intrapartum CD, neonatal asphyxia, and PPH in women underwent CD remained unchanged from May 1st 2015 to April 30th 2016. Conclusions: Our study shows that the rates of CD and MRCD in our department significantly were decreased over a year period (2015. 05.01~2016. 04.30), which may be due to the increasing use of NA during vaginal delivery by the help of NPLD. Key Words: Neuraxial Labor Analgesia; Cesarean Delivery; Maternal Request Cesarean Delivery
Matrine protects retinal ganglion cells from apoptosis in experimental optic neuritis
Authors: Kang Jian , Liu Shu-Qing , Song Yi-Fan , Wang Meng-Ru , Chu Yao-Juan , Shi Ya-Min , Zhang Feng-Yan , Zhu Lin 
Published: March 2020

Abstract
Background: Inflammatory demyelination and axonal injury of the optic nerve are hallmarks of optic neuritis (ON), which often occurs in multiple sclerosis and is a major cause of visual disturbance in young adults. Although a high dose of corticosteroids can promote visual recovery, it cannot prevent permanent neuronal damage. Novel and effective therapies are thus required. Given the recently defined capacity of matrine (MAT), a quinolizidine alkaloid derived from the herb Radix Sophorae flavescens, in immunomodulation and neuroprotection, we tested in this study the effect of matrine on rats with experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.
Results: MAT administration, started at disease onset, significantly suppressed optic nerve infiltration and demyelination, with reduced numbers of Iba1 + macrophages/microglia and CD4 + T cells, compared to those from vehicle-treated rats. Increased expression of neurofilaments, an axon marker, reduced numbers of apoptosis in retinal ganglion cells (RGCs), and reduced numbers of Iba1 + macrophages/microglia and CD4 + T cells were also observed in the retina after MAT treatment.
Conclusions: Taken as a whole, our results demonstrate that MAT attenuated inflammation, demyelination and axonal loss in the optic nerve, and protected RGCs from inflammation-induced cell death. MAT may therefore have potential as a novel treatment for this disease that may result in blindness.
Continuous intrapartum support to reduce primary cesarean in Mexico
Authors: Cardona-Torres Luz Maria , Leyva-Jimenez Rafael 
Published: March 2020

Abstract
Background

Cesarean deliveries are effective in saving maternal and infant lives, but only when they are necessary for medical reasons. In Mexico, the average cesarean delivery rate in 2015 was reported at 45%, the high incidence of cesarean deliveries is considered a problem of public health in the country, our purpose was to reduce the cesarean delivery rate for primary cesarean, in nulliparous women, term, singleton, vertex presentation and under 40 years through continuous intrapartum support provided by a professional nurse.

Methods

This was a historical control study, in a health institution in Mexico, in the period de July-December 2018. The control group received the usual obstetric care, without continuous intrapartum support. The study group received the usual obstetric care plus continuous intrapartum support, it was obtained the cesarean delivery rate, estimating the risk ratio, the absolute risk reduction and odds ratio, in addition, a binomial logistic regression model was carried out and was adjusted with possible covariates.

Results

In the study group the cesarean delivery rate was 1.7% (1 of 60) significantly lower than in the control group (29.1% (16 of 55) [X 2 = 17.13, df = 1, N = 115, p < .001], with a risk ratio of 0.06 (95% CI: 0.01 to 0.42), the absolute risk reduction was 27.4%, (95% CI: 15% - 40%), also the hours of labor were significantly lower (p < 0.001) in the study group (median = 6.7 hours, 95% CI: 6.0-8.1), than in the control group (median = 13.4 hours, 95% CI: 10.7 - 16.1) and no significant covariates were found.

Keywords: Cesarean delivery rate, Continuous intrapartum support, labor
Patient-reported quality indicators to evaluate physiotherapy care for hip and/or knee osteoarthritis- development and evaluation of the QUIPA tool.
Authors: Teo Pek Ling , Hinman Rana S , Egerton Thorlene , Dziedzic Krysia S , Kasza Jess , Bennell Kim L 
Published: March 2020

Abstract
Background: There is no physiotherapy-specific quality indicator tool available to evaluate physiotherapy care for people with hip and/or knee osteoarthritis (OA). This study aimed to develop a patient-reported quality indicator tool (QUIPA) for physiotherapy management of hip and knee OA and to assess its reliability and validity.
Methods: To develop the QUIPA tool, quality indicators were initially developed based on clinical guideline recommendations most relevant to physiotherapy practice and those of an existing generic OA quality indicator tool. Draft items were then further refined using patient focus groups. Test-retest reliability, construct validity (hypothesis testing) and criterion validity were then evaluated. Sixty-five people with hip and/or knee OA attended a single physiotherapy consultation and completed the QUIPA tool one, twelve- and thirteen-weeks after. Physiotherapists (n=9) completed the tool post-consultation. Patient test-retest reliability was assessed between weeks twelve and thirteen. Construct validity was assessed with three predefined hypotheses and criterion validity was based on agreement between physiotherapists and participants at week one.
Results: A draft list of 23 clinical guideline recommendations most relevant to physiotherapy was developed. Following feedback from three patient focus groups, the final QUIPA tool contained 18 items (three subscales) expressed in lay language. The test-retest reliability estimates (Cohen’s Kappa) for single items ranged from 0.30-0.83 with observed agreement of 64-94%. The intraclass correlation coefficient (ICC) and 95% confidence interval (CI) for the Assessment and Management Planning subscale was 0.70 (0.54, 0.81), Core Recommended Treatments subscale was 0.84 (0.75, 0.90), Adjunctive Treatments subscale was 0.70 (0.39, 0.87) and for the total QUIPA score was 0.80 (0.69, 0.88). All predefined hypotheses regarding construct validity were confirmed. However, agreement between physiotherapists and participants for single items showed large measurement error (Cohen’s Kappa estimates ranged from -0.04-0.59) with the ICC (95% CI) for the total score being 0.11 (-0.14, 0.34).
Conclusions: The QUIPA tool showed acceptable test-retest reliability for subscales and total score but inadequate reliability for individual items. Construct validity was confirmed but criterion validity for individual items, subscales and the total score was inadequate. Further research is needed to refine the QUIPA tool to improve its clinimetric properties before implementation.