bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attention‐dependent switching between intrinsic‐muscle and extrinsic‐visual coordinates during bimanual movements
Authors: Sakurada Takeshi , Kansaku Kenji 
Published: December 2020

AbstractInter‐limb coordination is achieved through multiple levels of motor control based on intrinsic‐muscle and extrinsic‐visual coordinates. Online visual feedback affects which of these coordinates is dominant, and visual perception is involved in the switching of motor coordination across the two hands; however, it remains unclear whether there is any role for attention in inter‐limb coordination. Therefore, we evaluated the effects of attention on the dominance of intrinsic‐muscle and extrinsic‐visual coordinates by investigating inter‐limb interference in the right or left hand during bimanual reaching movements, as induced by visual perturbations. We first showed an effect of differences in online visual feedback on bimanual coordination (Experiment 1). We then revealed that attention to visual cursors that directly affected the hand movement led to the dominance of the intrinsic‐muscle coordinates, which synchronized homologous muscle activities. In contrast, attention to an integrated visual object controlled by bilateral hand movements was associated with a preference for extrinsic‐visual coordinates to synchronize bilateral movement directions (Experiment 2). Thus, attention‐dependent switching between intrinsic‐muscle and extrinsic‐visual coordinates was observed during bimanual movements; extrinsic‐visual coordinates may enable goal‐directed bimanual movements at least for particular task requirements.
Resource selection in nasute termite: The role of social information
Authors: Silva Aline Nascimento Filgueira , Silva Cátila Regina , Santos Renan Edson Campelo , Arce Carla Cristina Marques , Araújo Ana Paula Albano , Cristaldo Paulo Fellipe 
Published: December 2020

AbstractDuring foraging, organisms need to assess the costs and benefits related to resources wanted. An energy‐efficient way of locating and deciding among new food sources is to use cues left by other organisms in the environment (i.e., social information). In the present study, manipulative bioassays were conducted to evaluate the role of intra‐ and interspecific chemical cues in the selection of food resource by Nasutitermes corniger (Termitidae: Nasutitermitinae). For this, we tested the hypothesis that individuals of N. corniger are able to perceive and use chemical cues by either colonies of the same species or from different species. Linear trail bioassays were conducted to verify whether N. corniger workers perceive and accept intra‐ and interspecific chemical cues. Then, resource bioassays were performed with a binary and multiple choices to evaluate whether the termite group's decision of food resources was based on intra‐ and/or interspecific chemical cues. In general, groups of N. corniger preferred baits with chemical cues of other intraspecific colonies or with undetectable cues (hexane solvent or interspecific cues) than those with their own chemical signals. These results suggest that intraspecific chemical cues seem to modulate the food resource selection in N. corniger, which may help researchers to better understand the use of habitat by termites.
Modelling seedling emergence in Paspalum species using environmental data from field experiments
Authors: Glison Nicolás , Batlla Diego , González Barrios Pablo , Viega Luis , Saldanha Sylvia , Musacchio Eduardo Mario , Rush Pablo , Speranza Pablo Rafael 
Published: December 2020

AbstractIn warm‐temperate regions, the adoption of warm‐season forage grasses has been hindered by low and unpredictable seedling emergence because of seed dormancy. Developing models driven by temperature (T) and soil water potential (Ψ) may provide tools for choosing adequate sowing conditions. Models are usually developed with controlled chamber germination data, but they can be built using field emergence and weather station data. Seedling emergence data of four Paspalum populations (two dallisgrass subspecies, bahiagrass and vaseygrass) were gathered from five experiments in three Campos locations (Buenos Aires, Montevideo and Salto) during two years, with fall and spring sowing dates and irrigated and non‐irrigated plots. Thermal and hydrothermal time models were used for emergence timing. The predictions were better for irrigated plots and fall sowings. For maximum emergence proportion (MEP), a mixed linear model was adjusted. Within a non‐irrigated treatment, the higher MEP was for early‐spring sowings, but the lowest for late‐spring ones. Additionally, a thermal time index (TTI) was modified to model MEP. A coefficient which weighs degree‐days accumulation according to the hydrothermal range (HTR) of each day was set. The HTRs were defined by T and Ψ thresholds. Thresholds and coefficient values were optimized by genotype until linear regressions between MEP and modified TTI achieved higher fit. Days with high temperature (>18°C or 20°C according to genotype) accumulated half or none of degree‐days when high‐ or mid‐soil water content was available, respectively. Differences among Paspalum genotypes, sowing date recommendations and modified TTI usefulness were discussed.
The intersection of COVID‐19, school, and headaches: Problems and solutions
Authors: Karvounides Dina , Marzouk Maya , Ross Alexandra C. , VanderPluym Juliana H. , Pettet Christina , Ladak Ali , Ziplow Jason , Patterson Gentile Carlyn , Turner Scott , Anto Marissa , Barmherzig Rebecca , Chadehumbe Madeline , Kalkbrenner Jocelyn , Malavolta Carrie P. , Clementi Michelle A. , Gerson Trevor , Szperka Christina L. 
Published: December 2020

AbstractObjectiveTo equip clinicians with recommendations specific to concerns related to the novel coronavirus disease 2019 (COVID‐19), which impact the physical, emotional, and social health of youth with headache disorders.BackgroundCOVID‐19 has affected societies on a global scale including children and youth with chronic headache disorders. Many concerns are predicted to arise in the 2020–2021 school year, whether classes are conducted in‐person or virtually.MethodsClinical impressions were combined with a review of the literature, although limited due to the recent nature of this issue.ResultsWe describe recommendations to support caregivers and youth as they face changes expected with the return to school in the fall of 2020.ConclusionAlthough there are significant concerns for caregivers and youth with migraine given the context of changes related to the pandemic, there are many recommendations that can help minimize exacerbations of the physical, emotional, and social health of youth with chronic migraine.
Recent developments in gastroesophageal mesenchymal tumours
Authors: Papke David J. , Hornick Jason L. 
Published: December 2020

The pathologist’s approach to gastroesophageal mesenchymal tumours has changed dramatically during the last 25 years. In particular, gastrointestinal stromal tumour (GIST) has evolved from a wastebasket mesenchymal tumour category to a precisely defined entity with an increasingly detailed genetic subclassification. This subclassification has brought gastrointestinal mesenchymal neoplasia into the realm of precision medicine, with specific treatments optimised for particular genetic subtypes. Molecular genetic data have also greatly improved our understanding of oesophageal mesenchymal tumours, including the discovery that so‐called ‘giant fibrovascular polyps’ in fact represent a clinically distinctive presentation of well‐differentiated liposarcoma. Here, we will focus on gastroesophageal mesenchymal tumours for which there have been recent developments in classification, molecular genetics or tumour biology: granular cell tumour, ‘giant fibrovascular polyp’/well‐differentiated liposarcoma, plexiform fibromyxoma, gastroblastoma and, of course, GIST.
Hybrid metaheuristics to solve a multiproduct two‐stage capacitated facility location problem
Authors: Mauri Geraldo Regis , Biajoli Fabrício Lacerda , Rabello Rômulo Louzada , Chaves Antônio Augusto , Ribeiro Glaydston Mattos , Lorena Luiz Antonio Nogueira 
Published: December 2020

AbstractThis paper presents two hybrid metaheuristics to solve a multiproduct two‐stage capacitated facility location problem (MP‐TSCFLP). In this problem, a set of different products must be transported from a set of plants to a set of intermediate depots (first stage) and from these depots to a set of customers (second stage). The objective is to minimize the cost related to open plants and depots plus the cost for transporting the products from the plants to the customers satisfying demand and capacity constraints. Recently, the methods clustering search (CS) and biased random‐key genetic algorithm (BRKGA) were successfully applied to solve a single‐product problem (SP‐TSCFLP). Therefore, in this paper we propose adaptations and implementations of these methods for handling with a multiproduct approach. To the best of our knowledge, CS and BRKGA presented the best results for the SP‐TSCFLP and both have not yet been applied to solve the problem with multiple products. Four sets of large‐sized instances with different characteristics are proposed and computational experiments compare the obtained results to those from a commercial solver.
Preferred‐oriented polycrystalline Y3Fe5O12 films grown on quartz with low microwave loss
Authors: Bhoi Biswanath , Diware Mangesh S. 
Published: December 2020

AbstractYttrium iron garnet (YIG) is an ideal magnetic insulator for room temperature microwave and spintronic applications. The growth of high‐quality YIG films on substrates other than isostructural Gadolinium gallium garnet (GGG) is a primary requirement to integrate with current semiconductor electronics. Here, we are presenting the growth of highly oriented YIG films on amorphous quartz substrates using pulsed laser deposition. Structural characterization suggests the growth of pure polycrystalline garnet phase with preferred (100) orientation. The 430‐nm thick YIG film shows a saturation magnetization (4πMS) of 1620 (92% of the bulk value of YIG) with a very small coercive field of 6 Oe and a minimum value for ferromagnetic resonance linewidth of 78 Oe for the magnetic field applied perpendicular to the film plane. Estimated damping constant shows reasonably low value, beneficial for realizing the applications integrated with semiconductor technology. Importantly, the formation of YIG with preferred orientation could unveil enormous opportunities in the preparation of textured or single crystal materials on amorphous substrates.
Efficacy of catheter ablation for patients with atrial fibrillation and atrial septal defect
Authors: Ogiso Masataka , Ejima Koichiro , Shoda Morio , Sugiyama Hisashi , Kato Ken , Tanaka Hiroyuki , Ohki Hirotaka , Miura Masaru , Hagiwara Nobuhisa 
Published: December 2020

AbstractIntroductionGiven that few studies investigated the efficacy of catheter ablation (CA) in patients with paroxysmal atrial fibrillation (AF) and atrial septal defect (ASD), this study evaluated its effectiveness in patients with paroxysmal AF and ASD.Methods and ResultsOf the 216 patients who underwent ASD device closure at two hospitals, 36 patients had paroxysmal AF. After April 2012, CA for AF was performed before ASD device closure (ASD‐CA group; n = 20). The ASD‐CA group had a significantly higher AF‐free survival rate after ASD device closure compared to patients without CA for AF before ASD device closure (ASD‐non‐CA group; n = 16) (ASD‐CA group: 2 patients vs. ASD‐non‐CA group: 9 patients; follow‐up period: 4.2 ± 2.5 years; log‐rank p = .01). In addition, the AF‐free survival rates were similar between the ASD‐CA group and 80 paroxysmal AF patients who underwent CA without any detectable structural heart disease (non‐SHD‐CA group). The two groups were matched by propensity scores for age, sex, and left atrium dimension (ASD‐CA group: 2 patients vs. non‐SHD‐CA group: 5 patients; follow‐up period: 3.3 ± 1.8 years; log‐rank p = .28).ConclusionCA for AF before ASD device closure might be an effective treatment option for patients with paroxysmal AF and ASD.
Predictors of the maximal oxygen consumption in adult patients with type 1 diabetes treated with personal insulin pumps
Authors: Matejko Bartłomiej , Tota Łukasz , Mrozińska Sandra , Morawska Małgorzata , Pałka Tomasz , Kieć‐Wilk Beata , Klupa Tomasz , Malecki Maciej T 
Published: December 2020

AbstractAims/IntroductionRegular physical activity for adults with type 1 diabetes mellitus improves cardiorespiratory fitness (CF) and quality of life. The aim of our study was to evaluate clinical and biochemical features that might be associated with CF in a homogenous group of adults with type 1 diabetes mellitus who are all treated with a personal insulin pump (continuous subcutaneous insulin infusion).Materials and MethodsWe assessed CF in 62 patients (74.2% of whom were men) who fulfilled the eligibility criteria. To determine maximal oxygen consumption, the march‐running test on the treadmill was carried out. Two hours before the test, the patients consumed a defined meal covered by a dose of rapid acting insulin analog that was reduced by 25% from their regular dose. Basal insulin infusion was reduced by 50% for an hour. Additionally, the Perceived Stress Scale‐10 questionnaire was used to measure the perception of stress.ResultsThere was no episode of severe hypoglycemia during or after the test. In the final model, independent predictors of maximal oxygen consumption were sex, body fat percentage, lactate at 20 min after CF test and Perceived Stress Scale‐10 score. Of interest, neither short‐term (continuous glucose monitoring) nor long‐term (glycosylated hemoglobin) metabolic control parameters were predictors of CF.ConclusionsIn our selected homogenous group of patients with type 1 diabetes mellitus treated with personal insulin pumps, higher CF was associated with a lower percentage of body fat, male sex, higher lactate level after the CF test and the Perceived Stress Scale‐10 score. The proposed protocol in our cohort proved to be safe with regard to glycemic control.
Intergroup contact and social change: An integrated Contact‐Collective Action Model
Authors: Hässler Tabea , Uluğ Özden Melis , Kappmeier Mariska , Travaglino Giovanni A. 
Published: December 2020

AbstractPrevious research has shown that positive intergroup contact among disadvantaged group members may predict a so‐called sedative effect according to which positive contact is associated with reduced support for social change. Conversely, positive contact is associated with increased support for social change toward equality among advantaged group members. This raises the important question of under which circumstances intergroup contact can encourage support for social change among both disadvantaged and advantaged groups. In this theoretical article, we tackle this question by introducing a new Integrated Contact‐Collective Action Model (ICCAM). We first provide an up‐to‐date review of how intergroup contact may promote or hinder social change for both disadvantaged and advantaged groups. We, then, use ICCAM to examine when the many forms of intergroup contact promote or hinder support for social change, proposing the existence of two different paths for disadvantaged and advantaged group members. Finally, we discuss the implications of the model for social intervention and make policy recommendations stemming from a review of available evidence.
Decline in Inpatient Volume at Rural Hospitals
Authors: Malone Tyler L. , Pink George H. , Holmes George M. 
Published: December 2020

AbstractPurposeTo investigate (1) all‐payer inpatient volume changes at rural hospitals and (2) whether trends in inpatient volume differ by organizational and geographic characteristics of the hospital and characteristics of the patient population.MethodsWe used a retrospective, longitudinal study design. Our study sample consisted of rural hospitals between 2011 and 2017. Inpatient volume was measured as inpatient average daily census (ADC). Additional measured hospital characteristics included census region, Medicare payment type, ownership type, number of beds, local competition, total margin, and whether the hospital was located in a Medicaid expansion state. Measured characteristics of the local patient population included total population size, percent of population aged 65 years or older, and percent of population in poverty. To identify predictors of inpatient volume trends, we fit a linear multiple regression model using generalized estimating equations.FindingsRural hospitals experienced an average change in ADC of −13% between 2011 and 2017. We found that hospital characteristics (eg, census region, Medicare payment type, ownership type, total margin, whether the hospital was located in a Medicaid expansion state) and patient population characteristics (eg, percent of population in poverty) were significant predictors of inpatient volume trends.ConclusionsTrends in inpatient volume differ by organizational and geographic characteristics of the hospital and characteristics of the patient population. Researchers and policy makers should continue to explore the causal mechanisms of inpatient volume decline and its role in the financial viability of rural hospitals.
Development of a novel AlphaLISA ImmunoAssay for Big angiotensin‐25
Authors: Nagata Sayaka , Fukuda Akihiro , Kikuchi Masao , Sato Yuji , Nagatomo Masanao , Aburaya Junko , Fujimoto Shouichi , Kitamura Kazuo 
Published: December 2020

AbstractWe previously described the discovery of Big angiotensin‐25 (Bang‐25), an angiotensin‐related peptide isolated from human urine. Bang‐25 consists of the first 25 amino acids of the N‐terminus of angiotensinogen (Aogen), with N‐linked glycosylation on the 14th amino acid and a cysteine conjugated to the 18th amino acid. Bang‐25 is rapidly converted into angiotensin II (Ang II) by chymase. Because Bang‐25 is widely distributed in human tissues, including islet cells in the pancreas and podocytes in the kidney, we hypothesized that it may participate in the Ang II production system in these tissues. To test this hypothesis, we developed a specific assay for Bang‐25 and used it to examine the urinary concentrations of Bang‐25 in patients with diabetes mellitus (DM). The assay used the Amplified Luminescent Proximity Homogeneous Assay (Alpha)‐based ELISA method (AlphaLISA) of PerkinElmer Japan and included antibodies specific to the N‐terminus of Ang II and the C‐terminus of Bang‐25. The AlphaLISA ImmunoAssay specifically recognized Bang‐25 and had no cross‐reactivity with Aogen or Ang I. Bang‐25 was detected in healthy volunteers' urine samples but not in their plasma samples. In patients with DM, the urinary Bang‐25 concentration was significantly higher than in healthy volunteers. Moreover, the results indicated that the Bang‐25 concentration in the urine may offer a different perspective on disease status from that provided by urinary albumin. This assay could provide a useful tool for determining urinary Bang‐25, which may prove an important biomarker for diabetic kidney disease.
Quantitative and dynamic cell polarity tracking in plant cells
Authors: Gong Yan , Varnau Rachel , Wallner Eva‐Sophie , Acharya Raghav , Bergmann Dominique C. , Cheung Lily S. 
Published: December 2020

Summary

Quantitative information on the spatiotemporal distribution of polarised proteins is central for understanding cell‐fate determination, yet collecting sufficient data for statistical analysis is difficult to accomplish with manual measurements.

Here we present Polarity Measurement (Pome), a semi‐automated pipeline for the quantification of cell polarity and demonstrate its application to a variety of developmental contexts.

Pome analysis reveals that, during asymmetric cell divisions in the Arabidopsis thaliana stomatal lineage, polarity proteins BASL and BRXL2 are more asynchronous and less mutually dependent than previously thought. A similar analysis of the linearly arrayed stomatal lineage of Brachypodium distachyon revealed that the MAPKKK BdYDA1 is segregated and polarised following asymmetrical divisions.

Our results demonstrate that Pome is a versatile tool, which by itself or combined with tissue‐level studies and advanced microscopy techniques can help to uncover new mechanisms of cell polarity.
Short‐period temporal repolarization dispersion in subjects with atrial fibrillation and decompensated heart failure
Authors: Piccirillo Gianfranco , Moscucci Federica , Bertani Gaetano , Lospinuso Ilaria , Sabatino Teresa , Zaccagnini Giulia , Crapanzano Davide , Diego Ilaria Di , Corrao Andrea , Rossi Pietro , Magrì Damiano 
Published: December 2020

AbstractBackground/objectivesThe association between chronic heart failure (CHF) and permanent atrial fibrillation is very frequent. The repolarization duration was already found predictive for atrial fibrillation. Aim of this study was to evaluate the influence of atrial fibrillation on short period repolarization variables in decompensated CHF patients.MethodWe used 5 min ECG recordings to assess the mean, standard deviation (SD), and normalized variance (NV) of the following variables: QT end (QTe), QT peak (QTp), and T peak to T end (Te) in 121 decompensated CHF, of whom 40 had permanent atrial fibrillation, too. We reported also the 30‐day mortality.ResultsQTpSD (p < .01), TeSD (p < .01), QTpVN (p < .01), and TeVN (p < .01) were higher in the atrial fibrillation than among sinus rhythm CHF subjects. Multivariable logistic analysis selected only TeSD (odd ratio, o.r.: 1.32, 95% confidence interval, c.i.: 1.06–1.65, p: .015) associated with atrial fibrillation. A total of 27 patients died during the 30‐days follow‐up (overall mortality rate 22%), 7 (18%), and 20 (25%) respectively in the atrial fibrillation and sinus rhythm patients. Furthermore, the following variables were associated to the morality risk: NT‐pro Brain Natriuretic Peptide (o.r.: 1.00, 95% c.i.: 1.00–1.00, p: .041), left ventricular end diastolic diameter (o.r.: 0.81, 95% c.i.: 0.67–0.96, p: .010), and Te mean (o.r.: 1.04, 95% c.i.: 1.02–1.09, p: .012).ConclusionIn decompensated CHF subjects, Te mean seems be associated to mortality and TeSD to the permanent atrial fibrillation. We could hypothesize that, during severe CHF, the multi‐level ionic CHF channel derangement could be critical in influencing these non‐invasive markers. (ClinicalTrials.gov number, NCT04127162).
A global survey of the gene network and key genes for oil accumulation in cultivated tetraploid cottons
Authors: Zhu De , Le Yu , Zhang Ruiting , Li Xiaojing , Lin Zhongxu 
Published: December 2020

SummaryTo enrich our knowledge about gene network of fatty acid biosynthesis in cottonseed, we conducted comparative transcriptome to reveal the differences in gene expression between Gossypium hirsutum and Gossypium barbadense during cottonseed development. The prolonged expression period and increased expression abundance of oil‐related genes are the main reasons for producing high seed oil content (SOC) in G. barbadense, which manifested as the bias of homeologous gene expression in Dt‐subgenome after 25 day postanthesis (DPA). The dynamic expression profile showed that SAD6 and FATA are more important for oil biosynthesis in G. barbadense than that in G. hirsutum. Three key transcription factors, WRI1, NF‐YB6 and DPBF2, showed their elite roles in regulating seed oil in cotton. We observed that sequence variations in the promoter region of BCCP2 genes might contribute to its divergence in expression level between the two species. Based on the quantitative trait loci (QTL) information of the seed oil content and utilizing additional G. barbadense introgression lines (ILs), we propose 21 candidate genes on the basis of their differential expression level, of which the GbSWEET and the GbACBP6 showed the potential functional to improve the oil content. Taken together, studying the different expression of oil‐related genes and their genetic regulation mechanisms between G. hirsutum and G. barbadense provide new insights to understanding the mechanism of fatty acid biosynthesis network and fatty acid genetic improving breeding in cotton.