bluuebunny/crossref_metadata_2025_split huggingface dataset:
Алельний поліморфізм гена eNOS у дітей, які страждають від бронхіальної астми, за еозинофільного та пауцигранулоцитарного субтипу запалення бронхів
Authors: Bezrukov L.O. , Koloskova O.K. , Bilous T.M. , Bohutska N.K. 
Published: December 2020

Метою роботи було вивчити вплив алельного поліморфізму гена eNOS, що кодує активність ендотеліальної NO-синтази та синтез монооксиду нітрогену в дихальних шляхах, на окремі клінічно-параклінічні показники бронхіальної астми в дітей шкільного віку за еозинофільного і пауцигранулоцитарного запального фенотипу. Обстежені 22 хворі на бронхіальну астму з еозинофільним характером запалення дихальних шляхів та 15 пацієнтів — із пауцигранулоцитарним. Проведено імунологічні, спірометричні дослідження, генотипування ендотеліальної NOS.Тяжкість бронхіальної астми у хворих із різним типом запалення бронхів суттєво не залежить від алельного поліморфізму гена eNOS. Відсутність мутацій гена eNOS у вигляді генотипу GG виявилася характернішою для хворих із пауцигранулоцитарним характером запалення бронхів, алельний поліморфізм GT/TT — для дітей з еозинофільним запаленням. За наявності алельного поліморфізму гена eNOS за генотипу GT/TT дітям із пауцигранулоцитарним характером запалення бронхів були притаманні частіші клінічні прояви атопічного дерматиту й алергічного риніту, більший індекс лабільності бронхів та нижча концентрація метаболітів NO в конденсаті повітря, що видихається.
Епідеміологія первинних імунодефіцитів в Україні за даними реєстру пацієнтів
Authors: Chernyshova L.I. , Bondarenko A.V. , Kostyuchenko L.V. , Savvo O.M. , Volokha A.P. , Rabosh O.V. 
Published: December 2020

Первинні імунодефіцити (ПІД) являють собою групу рідкісних вроджених захворювань системи імунітету. Виявлення ПІД, підрахунок їх кількості й ідентифікація нозологічних форм є надзвичайно актуальною проблемою педіатрії, оскільки це важливо для розробки заходів щодо діагностики та лікування. Метою роботи було вивчення частоти ПІД в Україні та їх нозологічних форм шляхом створення реєстру пацієнтів. У 27 адміністративних центрах України була зібрана інформація про всіх пацієнтів із ПІД, діагностованих протягом 1995–2014 рр. На початок 2015 р. у реєстр включено 814 пацієнтів, із них 684 — живі, серед яких 561 дітина та 123 пацієнти віком понад 18 років. Мінімальна частота ПІД становить 1,23 живого пацієнта на 100 тис. населення, мінімальна частота народження дитини із ПІД — 9,94 на 100 тис. народжених живими. Структура ПІД за ланкою ураження імунної системи в Україні близька до структури у світі, основні групи ПІД представлені 39 нозологічними формами. Отримані дані свідчать про недостатнє виявлення ПІД в Україні, тому залишається актуальним питання підвищення настороженості лікарів різних спеціальностей стосовно ПІД і своєчасного направлення пацієнтів на консультацію до дитячого імунолога.
The Drill Method with Realistic Approach to Improve Learning Outcomes of Descriptive Statistics in Higher Education
Authors: Dewi Novi Ayu Kristiana , Trisnawati Trisnawati , Kristina Marilin 
Published: December 2020

ABSTRAK Matakuliah statistik deskriptif memiliki peran penting dalam pembejaran di perguruan tinggi. Namun seringkali mahasiswa mengalami kesulitan untuk memahami konten materi statistik deskriptif. Penelitian ini bertujuan untuk mendeskripsikan peningkatan hasil belajar mahasiswa pada matakuliah statistik deskriptif dengan menggunakan metode drill. Jenis penelitian yang digunakan penelitian tindakan kelas yang dilakukan selama dua siklus. Jumlah sampel penelitian terdiri dari 35 mahasiswa semester dua yang berpartisipasi dalam pembelajaran statistik deskriptif. Pengumpulan data penelitian menggunakan instrumen yang berupa lembar observasi dan tes. Teknik analisis data yang digunakan adalah statistik deskriptif. Hasil penelitian menunjukkan bahwa penggunaan metode drill memiliki dampak terhadap peningkatan hasil belajar antara siklus I dan siklus II. Peningkatan hasil belajar mahasiswa pada siklus I diperoleh rata-rata 78,23, dan pada siklus II diperoleh rata-rata 87,14 sehingga terjadi peningkatan rata-rata hasil belajar sebesar 8,91. Berdasarkan hasil penelitian dapat disimpulkan bahwa penerapan metode drill dalam perkuliahan statistik deskriptif dapat meningkatkan hasil belajar mahasiswa pada matakuliah statistik deskriptif. Kata kunci: metode drill, hasil belajar statistik deskriptif, pendidikan tinggi AbstractDescriptive statistics courses have an important role in teaching and learning process in higher education level. However, students often have difficulty in understanding the content of descriptive statistics material. This research aimed to describe the improvement of student learning outcomes in the descriptive statistics subject by applying the drill method. The research employed classroom action research carried out in two cycles. The research consisted of 35 second semester students as samples who participated in descriptive statistics learning. The data collection method was conducted by using instruments in the form of observation sheets and tests while the research employed descriptive statistics as data analysis technique. The results showed that the use of the drill method had an impact on increasing learning outcomes between cycle I and cycle II. The increase in student learning outcomes in the first cycle obtained an average of 78.23, and in the second cycle it was obtained an average of 87.14. The result was giving evidence that there was an increase in the average learning outcomes of 8.91. Based on the research results, it can be concluded that the application of the drill method in descriptive statistics lectures can improve student learning outcomes in the descriptive statistics course. Keywords: drill method, descriptive statistics learning outcomes, higher education
KAJIAN METODA PELAKSANAAN PEKERJAAN PONDASI BORED PILE PADA TAHAP PERENCANAAN PELAKSANAAN
Authors: I Wayan Jawat  , Putu Panji Tresna Gita  , I Made Satria Dharmayoga  
Published: December 2020

Pondasi bored pile adalah pondasi tiang yang pemasangannya dilakukan dengan mengebor tanah lebih dahulu. Jenis pondasi bored pile banyak digunakan pada proyek konstruksi. Pelaksanaan pondasi bored pile yang dipilih disesuaikan dengan jenis tanah, kondisi medan serta metode konstruksi yang terpilih. Metode konstruksi merupakan penjabaran tata cara dan teknik-teknik pelaksanaan pekerjaan yang merupakan inti dari seluruh kegiatan dalam sistem manajemen konstruksi. Untuk itu menarik dilakukan kajian bagaimanakah metode pelaksanaan pondasi bored pile pada tahap perencanaan pelaksanaan pada proyek Pembangunan GOR di Abiansemal,Badung. Tahap perencanaan pelaksanaan merupakan kegiatan yang penting guna memberikan gambaran lebih rinci tentang strategi dan teknik pengerjaan secara efisien dan efektip baik dari segi waktu,mutu dan biaya. Adapun tujuan yang ingin dicapai dalam penelitian ini adalah melakukan kajian mengenai metode pelaksanaan pondasi pada tahap perencanaan pelaksanaan. Sehingga dapat memberikan sumbangan dalam pengembangan ilmu pengetahuan tentang penerapan teori metode pelaksanaan pondasi bored pile dan merupakan informasi bagi mereka yang tertarik dengan penelitian selanjutnya. Berdasarkan hasil kajian bahwa pada pekerjaan persiapan diawali dengan penentuan titik pusat pile dan penempatan alat bored pile. Pada pekerjaan pengeboran menggunakan metode wet drilling volume 1105 m dengan durasi 8 hari. Untuk pekerjaan pembesian volume 9309.61 kg dan durasi 13 hari didahului dengan proses fabrikasi dan dilanjutkan dengan pemasangan tulangan ke dalam lubang bor. Pengecoran dilakukan menggunakan pipa tremi, volume 74.394 m³ dengan durasi 11 hari. Selanjutnya dilakukan penentuan as pile cap dan pekerjaan galian,dilanjutkan dengan pekerjaan lantai pile cap dengan pasir urugan beton, volume 136.708 m³ selama 6 hari. Sebagai bekisting menggunakan batako dengan volume 237.474 m² dikerjakan selama 14 hari, dilanjutkan dengan pembentukan tulangan dan perakitan tulangan volume 5454.21 kg dengan durasi 9 hari serta metode pengecoran dilakukan dengan cara manual dengan volume 117.632 m³ dan durasi 14 hari.
ESTRATÉGIAS DE ENSINO PRATICADAS NAS INSTITUIÇÕES DE ENSINO SUPERIOR PRIVADA DE UM GRUPO EDUCACIONAL DO BRASIL FRENTE A PANDEMIA DO COVID-19
Authors: Ribeiro Henrique César Melo , Corrêa Rosany 
Published: December 2020

O objetivo do estudo foi investigar as estratégias de ensino praticadas nas Instituições de Ensino Superior Privadas de um Grupo Educacional do Brasil em decorrência da pandemia do COVID-19. A pesquisa adotou abordagem quantitativa e utilizou questionário fechado enviado para 60 gestores das Instituições de Ensino Superior Privadas (IESsP) de um Grupo Educacional do Brasil (GEB) como instrumento de coleta dos dados. O estudo relata que as IES do GEB já tinham adotado 20% em ensino a distância e ao implantar aulas remotas, as dificuldades observadas foram mínimas para os docentes, tendo sido mais sentidas pelos discentes. A pesquisa revela ainda que ao decidir para aulas síncronas, manteve uma proximidade entre professores e alunos, o que se mostrou muito proficuidade no momento de incerteza, quando se saiu do presencial para o ensino remoto de forma integral. Conclui-se que as IES do GEB foram estratégicas e saíram na frente no processo de aulas remotas, evitando a perda de alunos do semestre letivo, dando continuidade das aulas e no processo ensino aprendizagem, mostrando uma capacidade de reinventarem-se num momento que as empresas buscam formas melhores de atuar no mercado, sem perder a qualidade dos serviços prestados.
HUBUNGAN ANTARA KEMANDIRIAN DAN KONFORMITAS TERHADAP PENGAMBILAN KEPUTUSAN KARIR MAHASISWA SEMESTER 5 FAKULTAS ILMU PENDIDIKAN UNIVERSITAS NEGERI SEMARANG TAHUN 2019
Authors: Setiawan Irvan , Nusantoro Eko 
Published: December 2020

Abstract: The number of students entering tertiary institutions every year always increases. The importance of career decision making that must be done by students while in college must be right. This study aims to determine the relationship between independence and conformity on career decision making for 5th semester students FIP UNNES students in 2019. The design of this study is descriptive correlational. Data were collected using a psychological scale. The sampling technique uses proportioned randem sampling with a significant level of 5%, the total sample used 225 students from a total population of 997 students. Data analysis techniques used multiple linear regression by showing the results of a significant positive relationship between independence and conformity to career decision making with an ignorance result of 0.000 <0.05 and the value for F arithmetic was 61.216> F table 3.04.
Cloroquina
Authors: Guilherme Alves da Silva Wagner 
Published: December 2020

O presente texto tem por objetivo pensar o lugar das substâncias e de remédios nos processos de elaboração de Estado, tendo por ponto de partida o debate contemporâneo acerca da proposição da Cloroquina enquanto possibilidade de enfrentamento da pandemia de Sars-Cov-2. Pergunto-me, aqui, sobre o lugar do cotidiano e da vida ordinária em processos e acontecimentos extraordinários, bem como nos modos pelos quais o cotidiano se tornou uma arena de disputa. Assim, proponho que pensemos o efeito-cloroquina não apenas em seus termos biomédicos, mas nos regimes de verdade em que se insere e disputa, as dimensões morais, econômicas e jurídicas que põe em movimento. Assim, termino defendendo que Cloroquina faz Estado.
PERUBAHAN RASIONALISASI MORAL TINDAKAN AGRESI PADA MANTAN NARAPIDANA TERORIS DI INDONESIA (STUDI KASUS)
Authors: Limbu Diana , Prasetya Berta 
Published: December 2020

Penelitian ini bertujuan untuk menggambarkan bagaimana perubahan rasionalisasi moral tindakan agresi pada mantan narapidana teroris serta apa saja hal hal pendorong perubahan tersebut. Penelitian ini menggunakan pendekatan kualitatif yaitu studi kasus. Informasi utama dalam penelitian ini adalah seorang mantan teroris yang pernah terlibat aktif dalam pelatihan militer dan perang di Filipina Selatan serta terlibat kasus penyimpanan bom Semarang (Sri Redjeki). Data dianalisis dengan menggunakan teknik analisis model Milles dan Hebermen (1992), yakni mereduksi data, penyajian data hingga penarikan kesimpulan yang diambil dari hasil wawancara mendalam. Penelitian ini dianalisis dengan memperhatikan teori Tsang (2002) mengenai rasionalisasi moral serta teori Bandura (1991); Bandura, Barbaranelli, Ceprara, dan Pastorelli (1996), mengenai moral disengagement (pelepasan moral) pada subjek ditunjukkan adanya perubahan justifikasi moral, penggunaan penghalusan istilah, perbandingan menguntungkan, mengabaikan konsekuensi, dan menyalahkan orang serta yang menjadi hal-hal pendorong perubahan rasionalisasi moral yaitu pengalaman, peran keluarga, adanya kesibukan/konsentrasi usaha, peran agama, keinginan hidup bermakna, dan peran personal.
Strategic Marketing Planning Practice in SMEs and A Case Study in Turkey
Authors: Durmaz Yakup , Açıkgöz Ali 
Published: December 2020

This study aims to find whether strategic marketing planning is adequate in Small and Medium-sized Enterprises. Without efficient marketing, it is almost impossible for businesses to compete with others or to continue their businesses. This research studies the strategic marketing planning practices in SMEs in the Diyarbakır province of Turkey. The study was conducted on businesses in an organized industry site of Diyarbakır. For data collection, semi-structured interviews were made. The population of the research consists of people in charge of the SMEs. The results show that the SMEs on which the study was conducted were not on an adequate level when it comes to strategic marketing planning. According to the findings, the businesses in the study used dynamic pricing. The reason for this practice can be competition, exchange rates and the fluctuations in interest rates.
MARTÍNEZ MARTÍN, Laura. Voces de la ausencia. Las cartas privadas de los emigrantes asturianos a América (1856-1936). Gijón: Trea, 2019.
Authors: Monteagudo José Ignacio 
Published: December 2020

Resenha de MARTÍNEZ MARTÍN, Laura. Voces de la ausencia. Las cartas privadas de los emigrantes asturianos a América (1856-1936). Gijón: Trea, 2019.
KONDISI EKOSISTEM DAN VALUASI EKONOMI LAMUN DI PANTAI SAMUH, NUSA DUA, BALI
Authors: Lazaren Cornelia Coraima , Antara Made , Astarini Ida Ayu 
Published: December 2020

Seagrass ecosystems in addition to providing economic benefits also have ecological functions, so it is highly recommended to conserve these ecosystems in order to preserve spawning areas, nurseries and habitats for fish and other marine biota. This study aims to identify the condition of seagrass ecosystems in Samuh Beach, Nusa Dua, estimating the economic value of the seagrass ecosystems in Samuh Beach, Nusa Dua and formulating for sustainable management of seagrass ecosystems in Samuh Beach, Nusa Dua. The study was conducted in January-March 2020 at Samuh Beach, Nusa Dua, Bali. Data collected includes secondary data and primary data. Secondary data were collected from related institutions, while primary data were collected through purposive sampling and questionnaires. The analysis used was description analysis, calculation of the economic value of marine resources through a Total Economic Value (TEV) and DPSIR analysis. This study found that the actual condition of the seagrass ecosystem resources in Samuh Beach is currently in the category of less rich/less healthy due to natural factors (substrate conditions) and human activity (anthropogenic). The economic value of seagrass ecosystems at Samuh Beach Nusa Dua, Bali showed the total economic value reached IDR. 327,843,325 per year and seagrass ecosystem management strategies that can be applied in the coastal area of ??Samuh Beach are the development of marine ecotourism, stock enrichment, and rehabilitation of seagrass beds.
Keywords: Seagrass condition; TEV; economic valuation; Samuh beach.
ESTERIFIKASI DAN DEASIDIFIKASI MINYAK JELANTAH PADA PEMBUATAN BIODIESEL MENGGUNAKAN KATALIS ABU TONGKOL JAGUNG
Authors: Adu R. E. Y. 
Published: December 2020

Esterification and deacidification of waste cooking oil using alkali neutralization for biodiesel production using corncob ash as an alternative base catalyst was carried out. This study aimed to attainone of the desired transesterification conditionsby reducing free fatty acids content of waste cooking oil. Esterification was carried out by reacting waste cooking oil and methanol with certain volume ratio and acid catalyst (H2SO4) at 50oC for 4 hours. Deacidification was carried out by adding 0.5 N NaOH solution (15% excess alkali) at 60oC for 30 minutes. Esterification of waste cooking oil using acid catalyst before transesterification with corn cobs ash catalyst significantly increased the efficiency of free fatty acid conversion (92.69%) under volume ratio of 25% methanol /oil and 0.5% acid catalyst for 4 hours reaction. Deacidification of esterified oil with FFA content of 2.29 mg KOH /g oil through alkali neutralization at 55oC using alkaline content of 0.8 N reduces free fatty acid content to 0.47 mg KOH /g oil. Transesterification results showed that biodiesel component of waste cooking oil was dominated by polyunsaturated fatty acids (linoleic acid / C18-2), monounsaturated fatty acids (palmitic acid / C16-1 and oleic acid / C18-1) and saturated acids (palmitic / C16-0 and stearic acid / C18-0). Most of the biodiesel products were similar to those of the diesel physical characters. Biodiesel made of waste cooking oil meets the biodiesel quality standard (SNI 7182: 2015) for such parameters of density, viscosity, acid number, saponification value, iodine number and cetane. Esterification and neutralization process are effective in reducing free fatty acids content of waste cooking oil before being used in transesterification with corn cobs ash catalyst.
Keywords: esterification, neutralization, alkali, waste cooking oil, biodiesel, corn cobs ash
ANALISIS FATTY ACID ETHYL ESTER PADA RAMBUT MENGGUNAKAN GAS CHROMATOGRAPHY- MASS SPECTROMETRY UNTUK MENDIAGNOSIS PENYALAHGUNAAN ETANOL
Authors: Suaniti N. M. , Wiratama I W. , Suprihatin I. E. 
Published: December 2020

Fatty acid ethyl ester (FAEE) merupakan salah satu biomarker konsumsi etanol. Penelitian ini bertujuan untuk menganalisis senyawa FAEE dalam sampel rambut secara kualitatif dengan GC-MS. Pada penelitian ini dibuat campuran standar FAEE (Etil Pamlitat dan Etil Oleat) 100 ppm dengan perbandingan 1:1 kemudian dibuat variasi konsentrasi. Metode validasi standar FAEE diukur menggunakan GC-MS. Sampel rambut dipreparasi dengan cara didekontaminasi kemudian diekstraksi dan diinjeksikan ke sistem GC-MS. Hasil validasi diperoleh persamaan regresi linier yaitu, y = 240713,507x-147471,2353 untuk etil palmitat dan y = 58361,45x+242,5 untuk etil oleat dengan nilai koefisien korelasi (r2) berturut-turut sebesar 0,9996 dan 0,9999. Batas deteksi diperoleh sebesar 2,5522 ppm dan 0,0189 ppm, dengan batas kuantitasi sebesar 8,5073 ppm dan 0,0630 ppm. Nilai koefisien variansi diperoleh sebesar 3,59% dan 8,65 x 10-4%, dengan persen perolehan kembali sebesar 100,05% dan 100,08%. Hasil analisis menunjukkan, sampel rambut semua sukarelawan mengandung etil palmitat dan etil oleat pada waktu retensi 22,03 menit dan 23,83 menit.
Kata kunci: Fatty acid ethyl esters, Etil Palmitat, Etil Oleat, Alkohol, Etanol, Biomarker, GC-MS
Pengaruh City Branding dan City Image Terhadap Keputusan Berkunjung Wisatawan ke Kota Denpasar
Authors: Prabainastu Harsacitta 
Published: December 2020

One of the city that developing in increasing tourist visits is Denpasar. In increasing number of visits, one of the ways that government had to do is city branding. In this research city branding is influenced by city image, city branding influences visit decision, and city image influences visit decision. This research method uses qualitative approach with data collection techniques in qualitative and literature review. Findings of this research indicate that city branding has significant effect on city image, city branding has significant effect on visit decision and city image has significant effect on visit decision. Even though, there is relative answer, but the government of Denpasar city must realize this condition to develop Denpasar city with sustainable heritage tourism.
Key words : city branding, city image
Prostitusi dan Narkoba: Studi Etnografi Pariwisata Kelab Malam di Seminyak
Authors: Winawan I Komang Ayis , Mahagangga I Gusti Agung Oka , Ariwangsa I Made Bayu 
Published: December 2020

This research aims to provide a description of prostitution and drugs in nightclubs in Seminyak. Honesty, thus research not to find out who is right or wrong, precisely to emphasize understanding the tourism phenomenon from a different side. The research paradigm is qualitative with ethnographic methods, field research and qualitative techniques. The results showed that sex workers and drug users in Seminyak were not simple problems. Related to the development of the tourism sector, on the one hand, the pursuit of economic growth and the welfare of the community. But on the other hand, it triggers a lot of intrigue and strategies of actors or agent to remain, survive or get stronger in tourism practices in nightclubs. The field research finding controlled abandonment concept have strength evidence that prostitution and drugs exist but are needed according to the agent's interests.
Keywords: drugs, etnography, nigthclubs, prostitution, tourism
Pengelolaan Gua Cerme Sebagai Daya Tarik Wisata Berkelanjutan
Authors: Amelia Viona , Prasetyo Danang 
Published: December 2020

Cerme Cave is one of the objects of special interest tourist attraction which is used as one of the non-coastal tourism development projects by the dinas pariwisata kabupaten Bantul. This is done so that the distribution of tourists who visit, can be distributed evenly across all attractions in the Bantul regency. The decline in the level of tourist visits, limited attractions, and double levies has become an obstacle to the development of the Cerme Cave attraction, so a number of recommendations are needed to overcome and make these attractions sustainable. The research model used is qualitative through exploratory studies. The results showed that the problems that arose in these attractions include, dualism of management, the number of tourists being a priority, community participation is still low, lack of knowledge about tourism management in accordance with sustainable tourism management guidelines, do not have the intended target market, and marketing and limited promotions. Special interest tourism management strategies, including the targeted tourism segments must be clear, adequate human resource readiness in quality and quantity, facility development and accessibility in accordance with the landscape and tourist needs, promotions in accordance with the theme of tourist attraction attractions, so that the development strategy of Cerme Cave can be implemented optimally.

Keywords: sustainable tourism, cerme cave, management.