bluuebunny/crossref_metadata_2025_split huggingface dataset:
Massive earthquake countermeasures by establish muster point and migration path using network analysis in Matraman District, Jakarta, Indonesia
Authors: Randi Cattleya , Andromeda Zidny Ilma , Nazhifah Khairunnisa , Syahputra Reza , Mahmuddin Iskandarsyah , Septyandy Muhammad Rizqy 
Published: November 2019

Abstract
The issue of earthquake with magnitude 8 SR that threatens Jakarta has recently become a major concern due to the chance of catastrophic. This is closely related to the existence of a seismic gap located in Southern Java, Sunda Strait Megathrust. The seismic gap is a segment of an active fault known to produce a significant earthquake that shows no earthquake activities for an unusually long time. This situation implies that the moving crust is reserving potential energy which going to be release and resulting massive earthquake. The potential earthquake source located around 200 km from Jakarta which has densely populated and frequent annual disasters such as floods and fires. Matraman district is one of the densely populated areas in Jakarta with a population density of 319,291 per km2. Through GIS, this research uses network analysis methods to create an evacuation route in the event of a disaster. This method works with a cluster system to obtain the most effective paths in pre-determined zones. The evacuation route resulted from this analysis used 21 zones located in Matraman sub-district. Each zone has various evacuation time. The fastest time range between 1 to 3 minutes and the longest about 4 to 12 minutes. This evacuation route is also usable for SAR team and firefighter to reach the area of disaster.
The landslide analysis by using remote sensing & scoring calculation methods of tenang waras and its surrounding area, Muara Enim district, South Sumatera
Authors: Ardiansyah M , Hastuti E W D 
Published: November 2019

Abstract
Indonesian country geographically formed in the ring of fire zone. This situation trigger the occurrence of various natural disasters in Indonesia such as the earthquake, volcanic eruption and even tsunami waves, besides there is also one of the natural disaster which crucial enough and occur quite often, which is the landslide. The landslide disaster happens mostly in the highland area with the steep slope. This also applies in research area which located in Tenang Waras, South Sumatera. The research area located in high altitude having range of altitude from 402 masl to 912 masl, it also has steep enough slope and high ratio of rainfall. The methods of this research are study literature, geological and landslide zones mapping which analysed and combined with the laboratory analysis by using remote sensing software and also the scoring method which able to create high accuracy calculation from both of its analysis. The results of literature study shows that the research area often happens severe landslide disasters, result from geological mapping and landslide zones which combined with laboratory analysis known that there are several landslide zone which obtained from the landslide zone mapping, each of them are located in the north eastern, north western and south western part of research area, this is similar with the result of scoring method & remote sensing analysis by using the aspect of highest importance value of slope parameter with value of 5 and the lowest value is height parameter with the value of 2.
A study of coal upgrading in briquette making based on briquette characteristics using heated mechanical metods
Authors: Handayani H E , Ningsih Y B , Arifin M A 
Published: November 2019

Abstract
Indonesia has low quality coal reserves which are quite abundant. The low quality of coal is due to the inherent water content that is still quite high. Therefore, an upgrading process is needed. The upgrading process is intended to increase the calorific value of coal. The upgrading process can be applied to the process of coal briquettemaking. Generally, the manufacturing of low quality coal briquettes uses mechanical and heating methods in two different processes. In this study, the manufacturing of the briquettes uses the tools in a series of processes. The working principle of this tool is based on the strength of pressure and heating temperature. The maximum pressure is 900 psi, and the maximum heating temperature is 150°C. One of the important factors that determines the success of the upgrading process is the magnitude of heating temperature. The variations of heating temperature used are 50°C, 75°C, 100°C, 125°C, 150°C. The heating temperature affects the characteristics of coal briquettes produced. The heating temperature that produces the best quality coal briquettes is 150°C. The results of analysis of the coal briquette’s composition are as follows: the inherent water content is 11.00%, the volatile substance level is 46.48%, the ash content is 6.13%, the fixed carbon value is 36.39, and the calorific value is 5.235cal / gr.
Evaluation of groundnut shell as a reductant for microwave reduction of low grade banded iron ore
Authors: Rayapudi V , Dhawan N 
Published: November 2019

Abstract
This study investigates the utilization of low-grade banded iron ore for its utilization as a blast furnace feedstock. The complex association of the quartz-hematite phase and a fine liberation size prohibits the direct use of these ores in the steel production cycle. Conventional reduction experiments using different reductants yielded limited iron enrichment. Microwave carbothermal reduction using economical and abundantly available groundnut shell was investigated using a Taguchi L9 statistical design. The design optimal condition of 900W power, 20 min time and 3% equivalent carbon yielded an enriched iron concentrate with Fe 58% at 85.6% recovery. Characterization studies reveal the formation of sequential hematite, magnetite and wustite formation with groundnut shell dosage. The concentrate obtained can be used as feedstock for blast furnace burden. Microwave reduction was found better in terms of product control than conventional reduction, as fayalite formation was not observed.
Evaluation of geometric properties of regular and irregular particles of chalcedonite enrichment products from pulsating laboratory jig by means of dynamic image analysis method (DIA)
Authors: Krawczykowski D , Krawczykowska A , Gawenda T , Nad A 
Published: November 2019

Abstract
The aim of the paper was to evaluate the geometrical properties of regular and irregular chalcedonite particles contained in enrichment products obtained in a laboratory ring jig. Investigative programme included carrying out the tests of aggregate enrichment together with the vision analysis of regular and irregular particles of feed and enrichment products obtained from different layers of the jig bed. Various types of shape coefficients were calculated and the most effective among them for the assessment the particle shape, were selected. The particle size distribution of the feed and their enrichment products according to the minimum Feret’s diameter, were also determined. The results obtained by the vision system were discussed in the context of its potential utilization in evaluation of the enrichment process of mineral aggregates in a water jig.
Factor analysis in determining the quality of coal
Authors: Niedoba T , Pieta P , Surowiak A 
Published: November 2019

Abstract
The separation of coal material of three types of coals originating from three various Polish hard coal mines (types 31, 34.2 and 35, according to Polish nomenclature, which were steam coal, semi-coking coal and coking coal) into particle size fractions and then into particle density fractions was done and then the following parameters were measured for each particle size-density fraction: combustion heat, ash contents, sulfur contents, volatile parts contents, analytic moisture. In this way a 7-dimensional vector of data was created. Using methods of factor analysis the important features of coal were selected, which decide about their membership to individual types. To evaluate the appropriateness of the applied method the Bartlett’s sphericity test as well coefficient of Kaiser-Mayer-Olkin (KMO) were used. To select important factors the Kaiser criterion and Cattell’s scree test were used. The obtained results were compared with the results obtained in previous works by means of observation tunnels method. The results showed which particular features are crucial to define the type of coal what is also important to select appropriate method of its enrichment.
Physical separation methods, Part 1: A Review
Authors: Poloko N 
Published: November 2019

Abstract
Herein, the importance of physical separation methods of ores in mineral processing is widely acknowledged. Of interest is the magnetic separation, gravity concentration and sensor-based separation methods. The process of separating elements of value from gangue in ores depends on its chemical nature and mineralogical attributes hence the need for a profound characterization prior to physical separation. Some ores especially copper sulphides are readily available in nature in low grades usually less < 1% while some may appear relatively in small isolated deposits (Baba et al, 2012). Therefore, it is costly to extract a small portion of a purified metal from such ores. To circumvent high energy and costs when conducting relevant extraction operations, ores directly from mines can be processed physically before smelting, leaching, purifying or other recovery processes. Most physical separation plants and processes are adjunct to the mines to avoid transportation of a heavy ore with only a small portion of valuables. The aim of this review is to present an understanding on physical separation methods with emphasis on how they take advantage of ore physical properties to achieve separation. In addition, developments of these methods with growing technology is also presented.
RETRACTED: Experimental investigation of dry turning of AISI 1040 steel with TiN coated insert
Authors: Nair Sreejith S , Ramkumar T , Selva kumar M , Netto Fabian 
Published: November 2019

Abstract
Quality and productivity plays a pivotal part in the current manufacturing scenario. The current investigations are expected to evaluate the superlative handle environment which may fulfill the prerequisites of both quality as well as productivity. This work is centered on numerical modeling along with optimization model based on Box Behnken design strategy to optimize the machining parameters such as spindle speed, feed , depth of cut and nose radius on the reaction characteristics specifically, surface roughness (Ra) and material removal rate (MRR) during the dry turning of AISI 1040 steel utilizing TiN coated Carbide inserts. The results uncover that the spindle speed and the depth of cut are the foremost impacting factors that realize maximization of material removal rate and the minimization of surface roughness in dry turning of AISI 1040 steel. The optimization results illustrate that the desired combination of machining parameters for least surface roughness(Ra) of 1.15 μm and high MRR of 22 568.2 mm3 min−1 is obtained at the cutting speed of 1200 rpm, feed of 0.21 mm rev−1, depth of cut of 1.5 mm and nose radius of 1.2 mm.
Ethanol Withdrawal Alters the Oxidative State of the Heart Through AT1-Dependent Mechanisms
Authors: Assis Victor O , Gonzaga Natália A , Silva Carla B P , Pereira Lucas C , Padovan Cláudia M , Tirapelli Carlos R 
Published: November 2019

AbstractAimsWe investigated the cardiac effects of ethanol withdrawal and the possible role of AT1 receptors in such response.MethodsMale Wistar rats were treated with increasing doses of ethanol (3 to 9%, vol./vol.) for 21 days. The cardiac effects of ethanol withdrawal were investigated 48 h after abrupt discontinuation of ethanol. Some animals were orally treated with losartan (10 mg/kg/day), a selective AT1 receptor antagonist.ResultsEthanol withdrawal did not affect serum levels of creatine kinase (CK)-MB. Losartan prevented ethanol withdrawal-induced increase in superoxide anion (O2•−) production in the left ventricle (LV). However, ethanol withdrawal did no alter the levels of thiobarbituric acid reactive substances (TBARS) or the expression of Nox1, Nox2 or Nox4 were found in the LV. Ethanol withdrawal reduced the concentration of hydrogen peroxide (H2O2) in the LV and this response was prevented by losartan. Ethanol withdrawal increased catalase activity in the LV and losartan attenuated this response. No changes on superoxide dismutase (SOD) activity or expression were detected in the LV during ethanol withdrawal. The expression of AT1, AT2 or angiotensin converting enzyme (ACE) was not affected by ethanol withdrawal. Similarly, no changes on the expression of ERK1/2, SAPK/JNK, COX-1 or COX-2 were found in the LV during ethanol withdrawal.ConclusionsEthanol withdrawal altered the cardiac oxidative state through AT1-dependent mechanisms. Our findings showed a role for angiotensin II/AT1 receptors in the initial steps of the cardiac effects induced by ethanol withdrawal.
Chemotactic responses of the root-knot nematode Meloidogyne incognita to Streptomyces plicatus
Authors: Wang Pinyi , Sun Yan , Yang Liangliang , Hu Yan , Li Jiefang , Wang Jinxing , Zhang Fei , Liu Yajun 
Published: November 2019

ABSTRACT
Rhizosphere microorganisms play an important role in the interactions of many species in the rhizosphere, including soil nematodes. One hundred strains of rhizosphere actinomycetes were screened in vitro for their effects on the chemotactic behavior of the root-knot nematode, Meloidogyne incognita. Volatile compounds produced by the strain Streptomyces plicatus G demonstrated both strong attractant and repellent activities towards M. incognita. The compound dibenzofuran attracted M. incognita nematodes strongly, while compound benzothiazole repelled them. The chemotaxis of M. incognita was also tested under controlled conditions in pot experiments. Cultures of S. plicatus G and volatile dibenzofuran attracted M. incognita while volatile benzothiazole repelled them. The results showed that volatile compounds produced by rhizosphere actinomycetes could influence the chemotaxis of nematodes to a host. This study provides new information about the interrelationship between rhizosphere actinomycetes and nematodes that may be useful in preventing nematode parasitism of agricultural crops.
Ondansetron use in the first trimester of pregnancy and the risk of neonatal ventricular septal defect
Authors: Lemon Lara S , Bodnar Lisa M , Garrard William , Venkataramanan Raman , Platt Robert W , Marroquin Oscar C , Caritis Steve N 
Published: November 2019

AbstractBackgroundLiterature is divided regarding the risk of neonatal ventricular septal defect (VSD) associated with first trimester ondansetron use in pregnancy.MethodsWe evaluated the risk of VSD associated with first trimester exposure to intravenous or oral ondansetron in 33 677 deliveries at Magee–Womens Hospital in Pittsburgh, PA (2006–2014). Using log-binomial regression, we evaluated the risk: (1) in the full cohort, (2) using propensity score designs with both matching and inverse probability weighting and (3) utilizing clustered trajectory analysis evaluating the role of dose. Sensitivity analyses assessed the association between ondansetron and all recorded birth defects in aggregate.ResultsA total of 3733 (11%) pregnancies were exposed to ondansetron in the first trimester (dose range: 2.4–1008 mg). Ondansetron was associated with increased risk of VSD with risk ratios ranging from 1.7 [95% confidence interval (CI) 1.0–2.9] to 2.1 (95% CI 1.1–4.0) across methods. Risks correspond to one additional VSD for approximately every 330 pregnancies exposed in the first trimester. The association was dose-dependent with increased risk in women receiving highest cumulative doses compared with lowest doses [adjusted risk ratio: 3.2 (95% CI 1.0–9.9)]. The association between ondansetron and congenital malformations was diluted as the outcome included additional birth defects.ConclusionsFirst trimester ondansetron use is associated with an increased risk of neonatal VSD potentially driven by higher doses. This risk should be viewed in the context of risks attributable to severe untreated nausea and vomiting of pregnancy.
Anal Squamous Intraepithelial Lesions (SILs) in Human Immunodeficiency Virus–Positive Men Who Have Sex With Men: Incidence and Risk Factors of SIL and of Progression and Clearance of Low-Grade SILs
Authors: Jongen V W , Richel O , Marra E , Siegenbeek van Heukelom M L , van Eeden A , de Vries H J C , Cairo I , Prins J M , Schim van der Loeff M F 
Published: November 2019

AbstractBackgroundHuman immunodeficiency virus (HIV)–positive men who have sex with men (MSM) are at risk of anal squamous cell carcinoma. Data are limited on the natural history of the precursor to this carcinoma, anal squamous intraepithelial lesions (SILs).MethodsHIV-positive MSM were screened for histopathological SILs by means of high-resolution anoscopy (HRA). For participants without SILs at baseline, we estimated the cumulative incidence and risk factors for SILs. For those with low-grade SILs (LSILs) at baseline, the risk of progression to high-grade SILs (HSILs) and the clearance rate were estimated at the lesion level.ResultsOf 807 men without SILs at baseline, 107 underwent follow-up HRA between 1 to 4.5 years later. At the second visit 18 men (16.8%) showed LSIL, and 25 (23.4%) HSIL. Age was associated with incident LSILs (adjusted odds ratio [aOR], 2.10 per 10-year increase in age; P = .01). Of 393 men with LSILs at baseline, 114 underwent follow-up HRA 0.5 to 2.5 years later. Of the 177 LSILs found at baseline, 87 (49.2%) had cleared at the second visit, and 29 (16.4%) had progressed to HSILs.ConclusionIncident LSILs and HSILs were common during follow-up among HIV-positive MSM without dysplasia at baseline. Among men with LSILs at baseline, nearly half of these lesions cleared, and a small portion progressed.
Jejuno-jejunal intussusception secondary to diffuse intestinal lipomatosis
Authors: Tabone Renee Angela , DeGreve Tom , Webb Peita , Yuide Peter 
Published: November 2019

Abstract
A 25-year-old man presented to the emergency department with severe abdominal pain and vomiting. He had previously presented 10 days prior with similar symptoms. Computed tomography imaging showed a large jejuno-jejunal intussusception. Multiple intestinal masses were identified intraoperatively with the rare diagnosis of intestinal lipomatosis later confirmed via histopathology. Diagnosis and management of rare surgical pathologies is always challenging. Intussusception should always be considered as a differential diagnosis for abdominal pain in adults, as adult intussusception is typically due to a structural abnormality with majority of cases requiring surgical intervention. Exploratory laparotomy with segmental resection and primary anastomosis proved to be a successful approach in our case, with the patient having an uneventful recovery. Follow-up has consisted of gastrointestinal endoscopy and colonoscopy, which have not demonstrated any further lipomas.
Sin1-mediated mTOR signaling in cell growth, metabolism and immune response
Authors: Ruan Chun , Ouyang Xinxing , Liu Hongzhi , Li Song , Jin Jingsi , Tang Weiyi , Xia Yu , Su Bing 
Published: November 2019

AbstractThe mammalian target of rapamycin (mTOR) is an evolutionarily conserved Ser/Thr protein kinase with essential cellular function via processing various extracellular and intracellular inputs. Two distinct multi-protein mTOR complexes (mTORC), mTORC1 and mTORC2, have been identified and well characterized in eukaryotic cells from yeast to human. Sin1, which stands for Sty1/Spc1-interacting protein1, also known as mitogen-activated protein kinase (MAPK) associated protein (MAPKAP)1, is an evolutionarily conserved adaptor protein. Mammalian Sin1 interacts with many cellular proteins, but it has been widely studied as an essential component of mTORC2, and it is crucial not only for the assembly of mTORC2 but also for the regulation of its substrate specificity. In this review, we summarize our current knowledge of the structure and functions of Sin1, focusing specifically on its protein interaction network and its roles in the mTOR pathway that could account for various cellular functions of mTOR in growth, metabolism, immunity and cancer.
Evaluation of Inpatient Antimicrobial Regimens for Readmitted Outpatient Parenteral Antimicrobial Therapy (OPAT) Patients Receiving Daptomycin or Ertapenem for Ease of Administration
Authors: Britt Rachel S , LaSalvia Mary T , Padival Simi , Patel Parth , McCoy Christopher , Mahoney Monica V 
Published: November 2019

Abstract

Background
Outpatient parenteral antimicrobial therapy (OPAT) allows for long-course intravenous treatment of infections without lengthy hospital stays. Upon discharge, antimicrobial therapy may be broadened for “ease” of once-daily administration (EOA). Patients requiring subsequent readmission can be tailored to pre-OPAT regimens to minimize adverse effects. This study assessed continuation of EOA regimens upon hospital readmission during or immediately following OPAT.

Methods
This was a retrospective review of adults enrolled in OPAT and discharged on ertapenem or daptomycin for EOA, defined by the terms “convenience” or “EOA” in OPAT notes or by switching to ertapenem or daptomycin upon OPAT enrollment despite adequate therapy with narrower-spectrum agents. The primary outcome was the percentage of patients readmitted during or following their OPAT course and maintained on an EOA regimen. Secondary outcomes included inpatient therapy cost, rates of Clostridioides difficile infection, and adverse events.

Results
Of 188 patients receiving an OPAT EOA regimen, 71 were readmitted, representing 113 unique readmissions. Patients were mostly males (81%) aged 57 years. EOA regimens were continued in 27% of hospital readmissions. The Infectious Diseases (ID) team was consulted in 48% of readmissions, and the Antimicrobial Stewardship Program (ASP) intervened in 26%. Combined, this resulted in de-escalation in 28% of cases. C. difficile infections and adverse events occurred in 7% and 12% of readmissions respectively. The median acquisition cost of inpatient EOA regimens was $150 per readmission.

Conclusion
OPAT EOA regimens were continued in 27% of hospital readmissions indicating a role for improved indication documentation and collaboration between ID services, ASPs, and OPAT teams.
The paediatrician as a leader: A resident educational intervention for high-value care
Authors: Foulds Jessica L , Forbes Karen L 
Published: November 2019

Abstract
The American College of Physicians defines high-value care (HVC) as health care that balances clinical benefit with costs and harms with the goal of improving patient outcomes. We present a novel 2-hour workshop developed for general paediatric residents designed to promote reflective practice on resource stewardship and raise awareness of costs of medical care in hospitalized children. The workshop impact was assessed quantitatively and qualitatively. Preworkshop, 2-week postworkshop, and 6-month postworkshop electronic surveys were completed by 18 of 43 workshop participants (42% survey participation rate, 100% follow-up in postworkshop surveys) revealing increased knowledge and retention. Thematic analysis performed on ‘lessons learned’ and ‘action plans’ provided by participants at the end of the workshop yielded rich data with key findings from learners that included critical thinking about their management and reflecting on nonmonetary costs. Future directions include faculty development and assessment of impact on patient care.