bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined BRAF G469A mutation and echinoderm microtubule associated protein like-4-anaplastic lymphoma kinase rearrangement with resistance: A case report and review of literature
Authors: Guo Xuan , Liu Yan , Wang Yu-Ting , Liu Kan , Ding Hui 
Published: December 2024

BACKGROUND
Through deeper understanding of targetable driver mutations in non-small-cell lung cancer (NSCLC) over the past years, some patients with driver mutations have benefited from the targeted molecular therapies. Although the anaplastic lymphoma kinase and BRAF mutations are not frequent subtypes in NSCLC, the availability of several targeted-drugs has been confirmed through a series of clinical trials. But little is clear about the proper strategy in rare BRAF G469A mutation, not to mention co-exhibition of anaplastic lymphoma kinase and BRAF G469A mutations, which is extremely rare in NSCLC.
CASE SUMMARY
We present a patient to stage IVA lung adenocarcinoma with coexisting echinoderm microtubule associated protein like-4 rearrangement and BRAF G469A mutation. She received several targeted drugs with unintended resistance and suffered from unbearable adverse events.
CONCLUSION
Due to the rarity of co-mutations, the case not only enriches the limited literature on NSCLC harbouring BRAF G469A and echinoderm microtubule associated protein like-4 mutations, but also suggests the efficacy and safety of specific multiple-drug therapy in such patients.
Discovery of primary lung cancer following resection of rectal cancer lung metastasis: A case report
Authors: Zhou Fei-Yan , Song Fang-Hua , Cheng Zhen-Hao , Wu Sen 
Published: December 2024

BACKGROUND
Colorectal cancer (CRC) ranks high among the most common types of malignant tumors. The primary cause of cancer-related mortality is metastasis, with lung metastases accounting for 32.9% of all cases of metastatic CRC (MCRC). However, cases of MCRC in the lungs, which present concurrently with primary peripheral lung adenocarcinoma, are exceptionally rare.
CASE SUMMARY
This report describes the case of a 52-year-old female patient who, following a colonoscopy, was diagnosed with moderately differentiated adenocarcinoma based on rectal mucosal biopsy findings. A preoperative chest computed tomography scan revealed a ground-glass nodule in the right lung and a small nodule (approximately 0.6 cm in diameter) in the extramural basal segment of the left lower lobe, which suggested multiple lung metastases from rectal cancer. Subsequent treatment and follow-up led to a diagnosis of rectal cancer with left lung metastasis and peripheral adenocarcinoma of the lower lobe of the right lung.
CONCLUSION
This case report describes the therapeutic journey of a patient with lung metastasis from rectal cancer in addition to primary peripheral adenocarcinoma, thus underscoring the critical roles of multidisciplinary collaboration, personalized treatment strategies, and comprehensive patient rehabilitation guidance.
The Effect of Training, Education, and Knowledge on Improving Tax Consultant Performance Karya Artha Bhakti Group
Authors: Linggi Erik Amba , Mangetan Larissa , Bangkaran Natasya , Roreng Petrus Peleng , Beloan Bertha 
Published: December 2024

The Effect of Training, Education, and Knowledge on Improving the Performance of Karya Artha Bhakti Group Tax Consultants. This study aims to determine the effect of training, education, and knowledge on employee performance at Karya Artha Bhakti Group. The independent variables are training (X1), education (X2), and knowledge (X3), and the dependent variable is employee performance (Y). The population is made up of all 31 employees of Karya Artha Bhakti Group. The sampling technique is saturated sampling; data collection is done using questionnaires, and validity and reliability tests are carried out. The data analysis techniques employed in this study include descriptive analysis, data normality tests, f tests, and t tests. This study found that training has a positive and significant effect on employee performance. Education as a positive and significant effect on employee performance, and knowledge has a positive and significant effect on employee performance, so all hypotheses are accepted. Companies should continue to increase their investment in employee training and education.
Musicality without Humanity
Authors: Gamba Marco , Torti Valeria 
Published: December 2024

Dopo anni in cui lo studio delle abilità musicali in specie diverse dall’uomo è stato sporadico, l'indagine su questi elementi costitutivi (ad esempio, ritmo, variazione di frequenza) ha ricevuto un nuovo impulso. Utilizzando l’approccio comparativo, gli studi degli ultimi anni hanno dimostrato come l’indagine sul ritmo nelle manifestazioni vocali delle specie di primati possa dare risultati sorprendenti che ci aiutano a far luce sui fattori che possono aver agito come pressioni selettive nel corso dell'evoluzione dell'albero dei primati. Questo contributo si propone di passare in rassegna gli studi condotti nell'ultimo decennio sui primati e di capire come questi possano essere utili per ricostruire una filogenesi di alcune delle abilità che permettono all'uomo di fare musica.
Socio-economic Factors Influencing Grade 12 Accounting Learners’ Performance in the Eswatini General Certificate Secondary Examination
Authors: Mkhize Msizi Vitalis , Mtshali Muntuwenkosi , Sithebe Khumbuzile , Aliamutu Kansilembo Freddy , Adelaide Msomi Xolisile 
Published: December 2024

This study examined the influence of socio-economic factors on Grade 12 Accounting learners’ performance in the Eswatini Accounting General Certificate Secondary Examination (GCSE). An explanatory sequential, mixed-methods design was used. For the quantitative component of the study stratified random sampling was used to obtain a sample of 400 Accounting learners and 80 Accounting teachers. Questionnaires were used to collected quantitative data, which was analysed using Statistical Package for Social Sciences (SPSS) version 27. Purposive sampling was used to select 12 Accounting learners and 8 Accounting teachers for the qualitative component. Interviews were used to generate quantitative data which was analysed thematically. The study found that socio-economic factors that negatively influenced learners’ performance in Grade 12 Accounting GCSE in Eswatini included parents’ lack of interest and involvement in their children’s learning, as well as the family’s socio-economic status (income and background), with poverty and overcrowded living conditions playing a role. The study raises awareness of the socio-economic factors that are likely to influence learners’ academic performance in Grade 12 Accounting in emerging economies. To mitigate these factors, the researchers recommend that parents or guardians allocate a regular time and dedicated space at home for their child to do their homework and discuss their child’s progress regularly with their child’s teacher as strategies to support their child’s learning.
Heterotopic Ossification After Shoulder Arthroplasty: A Systematic Review
Authors: Nadeem Fahad A. , Hayes Caleb V. , Jones James R. , Hargreaves Mathew D. , Brabston Eugene W. , Casp Aaron J. , Momaya Amit M. , Evely Thomas B. 
Published: December 2024

Introduction:
Shoulder arthroplasty is increasing in incidence over time. One potential complication that is not well studied following shoulder arthroplasty is heterotopic ossification (HO), the abnormal growth of extraskeletal bone in soft tissue. HO has been described as a complication in total hip arthroplasty literature but less described in the setting of shoulder arthroplasty. The aim of this systematic review is to present available evidence regarding the incidence, risk factors, and potential management of HO after shoulder arthroplasty.

Methods:
A systematic search was conducted in June 2023 using Pubmed, Embase, and Ovid Medline databases to retrieve all relevant studies evaluating the occurrence of HO after shoulder arthroplasty. The search was done in duplicate, and a quality assessment of all studies was included.

Results:
A total of 170 studies were retrieved, of which 6 were included, involving 1,028 patients undergoing shoulder arthroplasty with 1,038 operated shoulders. HO developed postoperatively in 28% of the included shoulders and was symptomatic in 12% with most cases occurring in shoulders that developed osteoarthritis and cuff tear arthropathy. Men appear to have an increased risk of developing HO post shoulder arthroplasty. Fewer than 2% of HO shoulders went on to have revision surgery, and no notable differences were observed in the postoperative mean elevation and external rotation angles of non-HO and HO shoulders. In addition, no reported benefit of the use of nonsteroidal anti-inflammatory drugs was found against the formation of HO after shoulder arthroplasty.

Conclusion:
HO occurs in 28% of shoulder arthroplasties in our review. Most of these were asymptomatic in the reviewed articles. Male patients and revision surgery with osteoarthritis and cuff tear arthroplasty seem to be at higher risk of developing HO post shoulder arthroplasty. Nonsteroidal anti-inflammatory drugs seem to not prevent the development of HO after shoulder arthroplasty; yet, future studies are needed to verify this claim.

Level of Evidence:
Level III; Systematic Review.
Kemampuan Koneksi Matematis Mahasiswa pada Materi Aplikasi Barisan dan Deret dalam Ekonomi dan Bisnis
Authors: Sulisti Hidayu 
Published: December 2024

This study aims to identify the level of mathematical connection skills of students on the application material of rows and series in economics and business, and analyze the factors that influence it. This research is a descriptive research with a survey form. The research subjects were 1st semester students of IAIN Pontianak's Sharia Economics Study Program who had taken the course on the application of arithmetic ranks and series in economics and business. The procedure in this research consists of 3 stages, namely: 1) Preparation stage, 2) Implementation stage, 3) The final stage. The results of this study indicate that the mathematical connection skills of sharia economics students of IAIN Pontianak on the application material of rows and series in economics and business still need to be improved. Some students were able to answer all the questions correctly, but most were only able to answer some of the questions or none of them were correct. This shows that students' understanding of this material is very diverse. Some factors that may contribute to this result include: learning approach, lack of practice, perception of mathematics, and limited resources. To overcome this problem, various efforts are needed from both lecturers and students. Thus, it is hoped that students can be better prepared to face challenges in the world of work that require critical and analytical thinking skills.
Mammogram Reject Rate Analysis and Cause in Regional Hospitals in Saudi Arabia
Authors: Ashkar Laila 
Published: December 2024

Background: Technical repeats of mammograms cause increased radiation exposure to patients. Therefore, regular quality assurance needs to be established to ensure the standard of performance in any breast center. Reject/repeat (RA) analysis is a subjective evaluation of image quality where images judged to be of poor quality are categorized according to their cause. The aim of this study was to evaluate the total number of rejected mammograms, the most commonly repeated views, and the reasons in a regional hospital in Saudi Arabia.
Method: Retrospective data collection was obtained from the Hologic Selenia Dimensions Digital Mammography System from 1. Sept 2021 to 31. August 2024. A ‘Reject Analysis’ report, including reject rates, rejection causes, rejected projections, and the total number of mammographic exposures, was retrieved from the machine itself. Anonymized, rejected images were then exported and analyzed by the researcher.
Results: A total of 20792 exposures in the 3-year period were included in this study. There were 2475 repeat rejections, translating into an average reject rate of 11.9%. The most common reasons for repeat rejections were patient positioning, x-ray equipment failure, patient motion, and artifacts.
Conclusion: The reported RR rate of 11.9% is well above the <3% acceptable level recommended by most international guidelines, and more research is required to reveal the underlying cause. We believe that regular mammography RA is an effective means for exposure reduction among mammography patients and to continuously improve training programs and maintain the quality and performances of many breast centers.
Seleção de rota de aproveitamento e destino de resíduos de painéis solares fotovoltaicos no Ceará
Authors: Queiroz Washington Luiz Rodrigues de , Silva Fernando José Araújo da , Maia Marcus Vinicius 
Published: December 2024

A energia solar fotovoltaica deve se tornar a fonte de energia de crescimento mais rápido do mundo nas próximas décadas. Os sistemas de energia solar são sempre recomendados quando o assunto é sustentabilidade e são tidos como a energia do futuro, provocando uma grande mudança nos requisitos de recursos no setor de energia e produzindo grandes quantidades de instalações solares, que logo se transformarão em lixo eletrônico fazendo com que a demanda por componentes reciclados de painéis solares dispare nos próximos anos. O aumento na produção de energia solar e sua expansão em larga escala levanta questões sobre as necessidades de avanço na tecnologia do estudo da matéria-prima e a capacidade de reciclagem da indústria. No Ceará, graças a alta insolação que resulta em grande potencial energético, a capacidade instalada de sistemas de geração de energia solar aumenta exponencialmente a cada ano. Devido a esse crescimento, vêm sendo discutida a obsolescência desse sistema e quais as implicações de seu fim de vida. A Política Nacional de Resíduos Sólidos de 2010 e o Acordo Setorial de Eletroeletrônicos assinado em outubro de 2019, demonstram certa preocupação com a gestão de resíduos e orientam para uma destinação final ambientalmente adequada. O objetivo desse artigo é aplicar e avaliar um modelo de tomada de decisões(AHP) sobre possíveis alternativas tecnológicas de reciclagem de painéis fotovoltáicos utilizadas no Estado do Ceará.
Influence Shift Work on Work Fatigue in Oil and Gas Industry Workers: Literature Review
Authors: Rezki Dwinda  , Baiduri Widanarko  
Published: December 2024

Background: Petroleum and gas industry carries out business in exploration and exploitation activities as well as in the processing of crude oil, an industry that is faced with working conditions and a high level of risk of danger. The work system for workers in the oil and gas sector applies the system shift like shift 4 time rotation, or two week days shift tends to make workers experience higher levels of fatigue and fatigue-related work accidents. For know the influence shift work on work fatigue in oil and gas industry workers.
Method: This research uses the method literature review with the PRISMA approach (preferred reporting items for systematic reviews and meta-analyses). In the journal search carried out on database google scholar dan ScienceDirect with the keyword "Shift work”, “Work Fatigue”, “Oil and Gas Industry”. A total of 962 journals were identified, but 5 journals met the inclusion and exclusion criteria.
Results: Based on 962 journals identified, 5 journals were selected according to inclusion criteria and exclusion criteria. Work shifts, whether 12-hour rotational work shifts or 2-week rotational shifts for offshore workers, can influence work fatigue in oil and gas workers. Lack of hours of sleep and poor sleep quality and circadian rhythm are often found to be factors causing work fatigue in oil and gas workers. Work fatigue experienced by oil and gas workers has an impact on reducing work performance and work productivity.
Conclusion: Shift work has an effect on work fatigue in petroleum and gas industry workers.
The Relationship between Personal Hygiene, Maternal Health Status, and History of Diarrhea to Stunting Cases in Indonesia: Systematic Review
Authors: Serly Santiyah Serly Santiyah , Razak Rahmatillah , Budiastuti Anggun , Sunarsih Elvi , Ekasari Ranti 
Published: December 2024

Background: The government established a goal of a prevalence rate of 14% by the end of 2024 because the number of stunting cases in Indonesia is still high, at 21.6%. This review aims to provide the factors such as personal hygiene, maternal health status, and diarrhea that cause stunting and recommendations for more effective health policies to prevent stunting in Indonesia. The purpose of this study is to examine the connection between personal hygiene, maternal health status, and a history of diarrhea with the occurrence of stunting in Indonesia..
Method: This study uses a systematic review method on observational studies with a case control and cross-sectional research design conducted in Indonesia published between 2019 and 2024. Databases such as PubMed, ScienceDirect, and Google Scholar are used to search for eligible articles. The quality of the publication was then assessed using The JBI (Joanna Briggs Institute) Critical Appraisal Tools.
Result: A total of 210 articles were taken from the database, and 17 research articles were included in this study. In the article studied, the factors that are most often associated with stunting are personal hygiene practices (behavior of washing hands with soap), maternal weight, maternal height, and infectious diseases such as diarrhea related to stunting.
Conclusion: A study of 17 articles showed that personal hygiene, maternal health status during pregnancy, and history of diarrhea contributed significantly to the incidence of stunting in Indonesia. Poor personal hygiene and diarrheal infections can worsen children's nutritional status, increase the risk of infection, and inhibit optimal growth and development. These factors are an important component in efforts to prevent stunting through improving hygiene, maternal health, and infection management.
Evaluation of urban air pollution by metal contents of woody vegetation leaves in the urban ecosystem
Authors: Ali Zunara , Sultan Khawar , Zaman Qamar uz 
Published: December 2024

Urban air pollution is a major environmental concern, and it should be addressed on a priority basis for human health and the urban ecosystem. The study was performed to investigate and understand the spatial distribution and contamination levels in the leaves of selected plants (Eugenia jambolana, Morus alba, Dalbergia sissoo, Populus deltoides, Ficus religiosa, Ficus variegata, Cassia fistula, Eucalyptus camaldulensis, Melia azedarach, Psidium guajava, Pongamia pinnata, Callistemon citrinus, and Polyalthia longifolia) exposed to the polluted areas of Canal Road, Lahore. Metal concentrations (Pb, As, Cr, and Cd) in the leaves of the plants were analyzed using atomic absorption spectrometry (AAS). The contamination level of As (Average ~1.03 mg/kg) was found to be moderately low in all trees tested except in Eucalyptus camaldulensis (As~2.11 mg/kg). Lead (Pb) accumulation levels in the leaves were observed to be visibly higher in almost all samples (Average ~ 5.34 mg/kg) than the WHO recommended limit (2 mg/kg). Among all samples, Ficus religiosa was found to have the highest levels of Pb. The contamination trends of Cr were observed to be high (Average~1.06 mg/kg) in non-native species, specifically in Eucalyptus camaldulensis (3.21 mg/kg). The Cd concentrations were also found to be higher in all plant samples (Average ~1.90 mg/kg) than the WHO permissible limit (0.02 mg/kg) in plants. Principal Component Analysis (PCA), GIS, and Minitab-19 were also applied to the data. This work is important to set a baseline for future researchers to appraise pollution load in different areas in light of the findings of this study.
Vad kan en senneolitisk urnegrav på Lurö i Vänern berätta om kontakter och levnadssätt under senneolitikum?
Authors: Olsson Hans 
Published: December 2024

In the late neolitic (2300-1700 BC) there are several signs of drastic change compared to earlier parts of the neolitic. Now DNA and strontium analysis from parts of southern Sweden strongly suggests high mobility, not just from individuals, but for whole family groups. A recent excavation on the island of Lurö in lake Vänern contained the cremated bones from a human buried in the later part of the late neolitic. The bones from this person was put in a urn in the outskirts of the livingsite from the same period
Kauno XVII a. grigališkojo choralo giesmynas – dar viena paslaptis
Authors: Vilimas Jonas 
Published: December 2024

Senųjų grigališkojo choralo rankraščių, ypač XV–XVII a. I pusės, Lietuvoje nėra nedaug, todėl kiekvieno iki tol nežinoto ar mažai žinoto rankraščio atsiradimas yra svarbus įvykis. Vienas iš tokių iki šiol netyrinėtų rankraštinių giesmynų saugomas Kauno miesto muziejaus M. ir K. Petrauskų namuose. Straipsnio tikslas yra pristatyti šį rankraštį aptariant jo išorinius bruožus, vidinę struktūrą bei kai kurias jame surašytas giesmes, taip pat iškelti galimas jo kilmės prielaidas.
Dar vienas žvilgsnis į Vilniaus Antakalnio basųjų trinitorių ordino kapelos veiklą
Authors: Dacevič Alicja 
Published: December 2024

Straipsnyje pateikiama naujų žinių apie kelis 1760–1864 m. Vilniaus basųjų trinitorių ordino kapelos veiklos aspektus: galimą kapelos steigėją ir donatorių, narių skaičių, jų asmenvardžius bei instrumentų sąrašus. Publikacijoje pratęsiami muzikologų Vytauto Povilo Jurkšto ir Laimos Budzinauskienės basųjų trinitorių vienuolijos kapelos prie Išganytojo bažnyčios Antakalnyje veiklos tyrimai.
الاندفاعية وعلاقتها بالاستجابة الخاطئة في الاختبارات الموضوعية (الصح والخطأ- اختيار من متعدد) لدى عينة من طلاب جامعة نجران
Authors: حسن محمد خضر عبد المختار , الصمادي مروان صالح 
Published: December 2024

هدفت الدراسة إلى التعرف على الاندفاعية وعلاقتها بالاستجابة الخاطئة في الاختبارات الموضوعية (الصح والخطأ-اختيار من متعدد) لدى عينة من طلاب جامعة نجران. تكونت العينة من (133) طالباً من جامعة نجران، طبقت عليهم استبانة الاندفاعية واختبار موضوعي، باستخدام التحليل العاملي بطريقة الفاريمكس، واختبار(ت)، ومعاملات الارتباط أظهرت النتائج: أن بعض المتغيرات تسهم في (تقدير المادة)، ومتغير (بطيء الاستجابة |سريع الاستجابة) على الاندفاعية في الاستجابة لدى الطلاب بجامعة نجران بإسهام بسيط، توجد علاقة (سالبة) بين مجموع استجابات الطلاب على التأني في الإجابة عن الاختبارات الموضوعية، ومجموع استجابات الطلاب على الاندفاعية في الاستجابة على الاختبارات الموضوعية، بالإضافة إلى أنه لا توجد فروق دالة إحصائياً عند 0.05 بين متباطئي الاستجابة، وسريعي الاستجابة على الاختبار الموضوعي في ضوء استجابة الطلاب على استبانة الاندفاعية، وعدم وجود فروق ذات دلالة إحصائية عند مستوي 0.05 بين تقدير ممتاز (قلة الأخطاء)، وتقدير مقبول (كثرة الأخطاء) في الاختبار الموضوعي على استبانة الاندفاعية.
The Role of Elements in Visual Merchandising on Impulsive Buying in Retail Stores (Study on SW Market Stores in Bantul)
Authors: Liliyan Aditya 
Published: December 2024

This study aims to examine the influence of elements in visual merchandising on impulsive buying behavior at a minimarket called SW Market. Visual merchandising, which includes store layout, product display, and employee interaction, is considered important in influencing impulsive buying. We collected data from 190 respondents who had recent shopping experiences at a minimarket using a survey approach and a Likert-scale questionnaire. The results show that a well-structured store layout facilitates consumer navigation, while attractive product displays increase visual appeal and the desire to buy impulsively. In addition, positive interactions with employees create a pleasant shopping atmosphere and encourage spontaneous purchasing decisions. This study also found that the combination of the three elements has a significant synergistic impact on impulsive buying behavior. These findings provide practical implications for retailers to optimize visual merchandising strategies to improve shopping and sales experiences. This study contributes to the literature on consumer behavior with a focus on the unique dynamics of minimarkets in Indonesia.