bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diversidade cultural no contexto organizacional
Authors: Da Silva Pablo Marlon Medeiros , Vasconcelos César Ricardo Maia de 
Published: October 2019

O presente estudo tem como objetivo fazer um levantamento bibliométrico acerca das publicações sobre a diversidade cultural nas organizações na área de Administração nos últimos dez anos utilizando-se da base de dados da Scopus. A metodologia utilizada foi a pesquisa exploratória, com abordagem quantitativa, adotando-se a bibliometria como instrumento de coleta para fazer o levantamento das publicações na área da Administração. Como resultados, a pesquisa alcançou um número de cento e setenta e seis artigos publicados no período de 2008 a 2017, constatou que os Estados Unidos foi o país que mais investiu em trabalhos científicos sobre diversidade cultural, e apurou que, as universidades europeias, com destaque para as austríacas e holandesas, se destacaram em número de pesquisas nos anos explorados.
USO DE LAMA RESIDUAL DE CONCRETO COMO SUBSTITUTO DA CAL HIDRATADA PARA PRODUÇÃO DE ARGAMASSAS DE REVESTIMENTO
Authors: Bonfim Walter Batista , Carvalho Igor Mazon , De Paula Heber Martins 
Published: October 2019

RESUMO: A construção civil tem sido reconhecida como uma atividade responsável por grande degradação ambiental. Assim, a maior sustentabilidade nesse setor da economia pode ser melhorada através da adoção de “tecnologias limpas”, de forma a minimizar os impactos ambientais em termos de geração de resíduos e consumo de energia e materiais tradicionais. Ainda pouco estudada, a utilização da lama residual de concreto (LRC) como material alternativo para produção de argamassas pode ser uma alternativa viável. Assim sendo, o presente artigo tem como objetivo avaliar o desempenho mecânico de argamassas produzidas com a lama residual de concreto seca (LRC-S) como substituto total e parcial da cal hidratada, avaliando o seu comportamento por meio de ensaios de consistência, resistência à tração na flexão e à compressão, absorção de água por capilaridade e densidade. No estado fresco, foi constatado que a utilização da LRC-S possui um impacto negativo na trabalhabilidade das argamassas, sobretudo para taxas de substituição superiores a 75%, em massa. Por outro lado, a substituição da cal hidratada, em até 50% em massa, se mostra viável, apresentando propriedades mecânicas equivalentes ao traço tomado como referência.
ABSTRACT: Civil construction has been recognized as an activity responsible for major environmental degradation. Therefore, greater sustainability in this sector of the economy can be improved by adopting “clean technologies” to minimize environmental impacts in terms of waste generation and energy and material consumption. Still little studied, the use of concrete sludge waste (CSW) as an alternative material for the production of mortars can be a viable alternative. The purpose of this study is to evaluate the mechanical performance of mortars produced with dry sludge as a total and partial substitute for hydrated lime, evaluating its behavior through tests of consistency, flexural strength and compression, water absorption by capillarity and density. In the fresh state, it was found that the use of CSW has a negative impact on the workability of mortars, especially for replacement rates above 75% by mass. On the other hand, the substitution of hydrated lime, up to 50% by mass, is feasible, presenting mechanical properties equivalent to the mix taken as reference.
Environmental Performance and Firm Value: Testing the Role of Firm Reputation
Authors: Khanifah Khanifah , Isgiyarta Jaka , Alfiana Fitri , Udin Udin 
Published: October 2019

This study aims to analyze the empirical evidence about the effect of environmental performance on firm value mediated by firm reputation. The sample of this study is the mining industry sectors listed on the Indonesia Stock Exchange from 2015 to 2018. The data is analyzed using partial least squares based structural equation modeling (PLS-SEM) with WarpPLS 6.0 software. The results show that environmental performance has a positive and significant effect on firm reputation. In contrast to the expectation, environmental performance has a negative and significant effect on firm value. Firm reputation further becomes a significant mediator in the relationship between environmental performance and firm value. These findings recommend for future studies to expand the objects and extend the observation period.
3D Printed Cartilage‐Like Tissue Constructs with Spatially Controlled Mechanical Properties
Authors: de Melo Bruna A. G. , Jodat Yasamin A. , Mehrotra Shreya , Calabrese Michelle A. , Kamperman Tom , Mandal Biman B. , Santana Maria H. A. , Alsberg Eben , Leijten Jeroen , Shin Su Ryon 
Published: October 2019

AbstractDeveloping biomimetic cartilaginous tissues that support locomotion while maintaining chondrogenic behavior is a major challenge in the tissue engineering field. Specifically, while locomotive forces demand tissues with strong mechanical properties, chondrogenesis requires a soft microenvironment. To address this challenge, 3D cartilage‐like tissue is fabricated using two biomaterials with different mechanical properties: a hard biomaterial to reflect the macromechanical properties of native cartilage, and a soft biomaterial to create a chondrogenic microenvironment. To this end, a bath composed of an interpenetrating polymer network (IPN) of polyethylene glycol (PEG) and alginate hydrogel (MPa order compressive modulus) is developed as an extracellular matrix (ECM) with self‐healing properties. Within this bath supplemented with thrombin, human mesenchymal stem cell (hMSC) spheroids embedded in fibrinogen are 3D bioprinted, creating a soft microenvironment composed of fibrin (kPa order compressive modulus) that simulate cartilage's pericellular matrix and allow a fast diffusion of nutrients. The bioprinted hMSC spheroids present high viability and chondrogenic‐like behavior without adversely affecting the macromechanical properties of the tissue. Therefore, the ability to locally bioprint a soft and cell stimulating biomaterial inside of a mechanically robust hydrogel is demonstrated, thereby uncoupling the micro‐ and macromechanical properties of the 3D printed tissues such as cartilage.
Synthesis and Enhancement of Electroactive Biomass/Polypyrrole Hydrogels for High Performance Flexible All‐Solid‐State Supercapacitors
Authors: Peng Zhiyuan , Wang Chuanzhi , Zhang Zhicheng , Zhong Wenbin 
Published: October 2019

AbstractRecently, electroactive biomass‐based hydrogels have attracted great attention for flexible supercapacitor electrodes due to its porous, renewable, earth‐abundant, low‐cost, and environmentally friendly characters. However, it is challenging to facilely prepare biomass‐based hydrogels with simultaneously possesses high mechanical strength and excellent electrochemical performance. In this work, the lignosulfonate/polypyrrole (Lig/PPy) hydrogel (LP54) is obtained. In order to further improve the mechanical strength and electrochemical performance of LP54, functionalized porous carbon nanospheres/lignosulfonate/polypyrrole hydrogel (FPCSLP54) is prepared by introducing a trace of FPCS (≈4.5 wt%) fabricated by hydrothermal treatment the mixture of PCS and pyrrole into the prepared LP54 system. FPCS can be uniformly anchored into Lig/PPy framework. The LP54 and FPCSLP54 exhibit compressive strength of 6.0 and 9.3 kPa with the water content of 94.9% and 94.3%, respectively. Meanwhile, as‐prepared LP54 and FPCSLP54 are separately assembled into symmetric flexible supercapacitors with cellulose/H2SO4 hydrogel electrolytes, which exhibit superior areal capacitance (463 and 522 mF cm−2), good rate capability and outstanding energy density (41.2 and 72.5 µWh cm−2). Remarkably, flexible supercapacitors present outstanding electrochemical stability even suffering 1000 bending cycles. In this work, the strategy to construct electroactive biomass‐based hydrogels is contributed and a new method to enhance the properties of hydrogels is provided.
A Layered Inorganic–Organic Open Framework Material as a 4 V Positive Electrode with High‐Rate Performance for K‐Ion Batteries
Authors: Hameed Abdulrahman Shahul , Katogi Akihiro , Kubota Kei , Komaba Shinichi 
Published: October 2019

AbstractK‐ion batteries (KIBs) are promising for large‐scale energy storage owing to various advantages like the high abundance of potassium resources in the Earth's crust, high operational potentials, and high power due to fast diffusion of K+ ions. However, to realize the practical application of KIBs, electrode materials are needed with high operational voltage, good capacity, long cycle life, and low‐cost. This work reports a layered open framework material, K2[(VOHPO4)2(C2O4)], composited with reduced graphene oxide (rGO) as a 4 V positive electrode material for KIBs. The material is prepared by a simple precipitation reaction at room temperature. The material demonstrates reversible K‐extraction/insertion with conventional carbonate ester KPF6 solutions; however, with low specific capacity and low Coulombic efficiency. A high discharge capacity of >100 mAh g−1 with good cycling stability and higher Coulombic efficiency is achieved in a highly concentrated electrolyte, 7 mol kg−1 of potassium bis(fluorosulfonyl)amide (KFSA) in dimethoxyethane (DME) at 0.1 C rate. Due to the facile migration of K+ ions in the framework, the material exhibits excellent rate capability with a discharge capacity of 80 mAh g−1 at 10 C rate, and a good capacity retention of 67% after 500 cycles at 2 C rate.
Asymmetric hybridization in Central European populations of theDryopteris carthusianagroup
Authors: Hornych Ondřej , Ekrt Libor , Riedel Felix , Koutecký Petr , Košnar Jiří 
Published: October 2019

PremiseHybridization is a key process in plant speciation. Despite its importance, there is no detailed study of hybridization rates in fern populations. A proper estimate of hybridization rates is needed to understand factors regulating hybridization.MethodsWe studied hybridization in the EuropeanDryopteris carthusianagroup, represented by one diploid and two tetraploid species and their hybrids. We sampled ~100 individuals per population in 40 mixed populations of theD. carthusianagroup across Europe. All plants were identified by measuring genome size (DAPIstaining) using flow cytometry. To determine the maternal parentage of hybrids, we sequenced the chloroplast regiontrnL–trnF of all taxa involved.ResultsWe found hybrids in 85% of populations. TriploidD. ×ambroseaeoccurred in every population that included both parent species and is most abundant when the parent species are equally abundant. By contrast, tetraploidD. ×deweveriwas rare (15 individuals total) and triploidD. ×sarvelaewas absent. The parentage of hybrid taxa is asymmetric. Despite expectations from previous studies, tetraploidD. dilatatais the predominant male parent of its triploid hybrid.ConclusionsThis is a thorough investigation of hybridization rates in natural populations of ferns. Hybridization rates differ greatly even among closely related fern taxa. In contrast to angiosperms, our data suggest that hybridization rates are highest in balanced parent populations and support the notion that some ferns possess very weak barriers to hybridization. Our results from sequencing cpDNAchallenge established notions about the correlation of ploidy level and mating tendencies.
Grange syndrome due to homozygous YY1AP1 missense rare variants
Authors: Ciuffetelli Alamo Isabella V. , Kwartler Callie S. , Regalado Ellen R. , Afifi Rana O. , Parkash Sandhya , Rideout Andrea , Guo Dong‐chuan , Milewicz Dianna M. 
Published: October 2019

AbstractGrange syndrome (OMIM 602531) is an autosomal recessive condition characterized by severe early onset vascular occlusive disease and variable penetrance of brachydactyly, syndactyly, bone fragility, and learning disabilities. Grange syndrome is caused by homozygous or compound heterozygous loss‐of‐function variants in the YYA1P1 gene. We report on the case of a 53‐year old female with novel homozygous missense variants in YYA1P1 (c.1079C>T, p.Pro360Leu), presenting with a history of brachysyndactyly, hypertension, and ischemic stroke. Imaging studies revealed stenosis of the bilateral internal carotid with extensive collateralization of cerebral vessels in a moyamoya‐like pattern, along with stenosis in the splenic, common hepatic, celiac, left renal, and superior mesenteric arteries. Functional studies conducted with the patient's dermal fibroblasts suggest that the p.Pro360Leu variant decreases the stability of the YY1AP1 protein. This is the first report of a missense variant associated with Grange syndrome characterized by later onset of vascular disease and a lack of developmental delay and bone fragility.
Coagulation/flocculation process for marble processing plant effluent: Modelling and optimization through response surface methodology
Authors: Çırak Mustafa , Atay Hüsnügül Yilmaz 
Published: October 2019

AbstractIn this study, the coagulation‐flocculation of a wastewater discharged from a marble processing plant was statistically analyzed and optimized. To make a systematic investigation on the coagulation‐flocculation of the highly turbid wastewater (>1000 NTU), the response surface methodology was used to estimate a capable quadratic model with R‐squared value of 98.84%. According to this model, the most critical parameter was the suspension pH with a p‐value < 0.0001. Furthermore, the PEO‐flocculant was proven as a substantial agglomerating reagent specifically at pH 12. On the other hand, no significant turbidity removal was observed upon the addition of the Fe‐coagulant. When the experimental parameters of the coagulation‐flocculation were optimized, it was found out that the minimum supernatant turbidity value of 3.81 NTU can be achieved by using the minimum amount of the Fe‐coagulant:50 mg/l, and the maximum amount of the PEO‐flocculant of 1.5 ppm at pH 11.5‐12.0. In conclusion, it was proved that the significance of the calcium dissolved from the marble particles was greater than the Fe‐coagulant in this process. The hydrolyzed calcium (CaOH+) species established a chemical bridge between the particle and the polymer and, as a result, enhanced the performance of the flocculation at the alkaline pH values.
High‐toughness, environment‐friendly solid epoxy resins: Preparation, mechanical performance, curing behavior, and thermal properties
Authors: Yang Jiayao , He Xingwei , Wang Hengxu , Liu Xiaohuan , Lin Peng , Yang Shengxiang , Fu Shenyuan 
Published: October 2019

ABSTRACTThe development of a facile and efficient approach to prepare high‐toughness epoxy resin is vital but has remained an enormous challenge. Herein, we have developed a high‐performance environment‐friendly solid epoxy resin modified with epoxidized hydroxyl‐terminated polybutadiene (EHTPB)viaone‐step melt blending. The characterization, mechanical performance, curing behavior, and thermal properties of EHTPB‐modified epoxy resin were investigated. EHTPB‐modified epoxy resin exhibited excellent toughness with a 100% increase in elongation at break of tensile than that of neat epoxy resin. The transfer stress and dissipated energy in the rubber phase were predominant mechanisms of toughening. The toughening effect of EHTPB on solid epoxy resin was better than that of some of the previously reported liquid epoxy resins. Meanwhile, at 10 wt % of EHTPB loading, the EHTPB‐modified epoxy resin displayed high strength and 22 and 101% improvement of flexural strength and impact strength, respectively. Moreover, at 10 wt % of EHTPB loading, the activation energy of EHTPB‐modified epoxy resin for curing reaction decreased from 73.89 to 65.12 kJ·mol−1, which is beneficial for the curing reaction. Furthermore, EHTPB‐modified epoxy resin had a good thermal stability and the initial degradation temperature increased from 249 to 313 °C at 10 wt % of EHTPB loading. This work provides a simple‐preparation and highly efficient and large‐scale approach for the production of high‐toughness environment‐friendly solid epoxy resins. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2020,137, 48596.
Clavicle in Carnivorans: A Forgotten Bone
Authors: de Souza Junior Paulo , Viotto‐Souza Wilson , Mendes Vanessa Pereira , Bernardes Fernanda Coelho Simas , dos Anjos Bruno Leite , Abidu‐Figueiredo Marcelo , Santos André Luiz Quagliatto 
Published: October 2019

ABSTRACTThe clavicle is a bone whose development is related to the versatility of the thoracic limbs in mammals. Studies with vestigial structures are scarce and controversial, especially in the order Carnivora. The objective of this study was to verify the presence and to investigate the shape and constitution of the clavicle in neotropical carnivores. In order to do this, 108 cadavers of 19 different species were collected dead on highways and were analyzed. The clavicles were submitted to dissections, longitudinal length measurements, radiographs, histological sections and, in some cases, diaphanization. Sixteen of the 19 species had clavicles in both sides, being significantly larger (P < 0.05) and distinctly more radiopaque in the felids than in the other families. There were no macro or microscopic evidence of clavicle in the specimens of Nasua nasua (n = 6), Conepatus semistriatus (n = 2), and Conepatus chinga (n = 1). The clavicle of the males of Lycalopex gymnocercus, Galictis cuja, and Leopardus geoffroyi was significantly larger (P < 0.05). The predominating contour of the clavicles was a thin stick with cranial convexity. The histological sections demonstrated compact bone consisting of trabecula and lamellae filled by bone marrow and different levels of occupation by chondroid matrix. It can be proposed the clavicles of the order Carnivora, although vestigial and rarely absent, have their presence, constitution and shape more associated with the phylogenetic proximity and evolutionary history of the species than to the variety of movements the thoracic limbs perform in free‐living conditions. Anat Rec, 2019. © 2019 American Association for Anatomy Anat Rec, 303:1831–1841, 2020. © 2019 American Association for Anatomy
Community through Culture: From Insects to Whales
Authors: Allen Jenny A. 
Published: October 2019

AbstractIt has become increasingly clear that social learning and culture occur much more broadly, and in a wider variety of animal communities, than initially believed. Recent research has expanded the list to include insects, fishes, elephants, and cetaceans. Such diversity allows scientists to expand the scope of potential research questions, which can help form a more complete understanding of animal culture than any single species can provide on its own. It is crucial to understand how culture and social learning present in different communities, as well as what influences community structure and culture may have on one another, so that the results across these different studies may most effectively inform one another. This review presents an overview of social learning in species across a spectrum of community structures, providing the necessary infrastructure to allow a comparison of studies that will help move the field of animal culture forward.
Fostering Systems Thinking in Biological Education Using the Example of Plant Hormones
Authors: Robischon Marcel 
Published: October 2019

AbstractSystems thinking is an increasingly recognized paradigm in education in both natural and social sciences, a particular focus being, naturally, in biology. This article argues that plant biology, and in particular, plant hormonal signaling, provides highly illustrative models for learning and teaching in a systems paradigm, because it offers examples of highly complex networks, ranging from the molecular‐ to ecosystem‐scale, and in addition lends itself to the use of real‐life biological objects.
Fisetin, a phytopolyphenol, targets apoptotic and necroptotic cell death in HepG2 cells
Authors: Sundarraj Kiruthika , Raghunath Azhwar , Panneerselvam Lakshmikanthan , Perumal Ekambaram 
Published: October 2019

AbstractFisetin (3,7,3′,4′‐tetrahydroxyflavone), a bioactive dietary flavonoid, intrigued scientists for its anticancer potential against various cancer types. We investigated the fisetin‐induced inhibition of growth and survival of human hepatocellular carcinoma. Fisetin decreased cell viability and proliferation of HepG2 cells as revealed from MTT and clonogenicity assays. Cell cycle arrest in the G2/M phase was observed. Annexin V/propidium iodide (PI) staining followed by flow cytometry revealed that fisetin induced both apoptosis and necroptosis in HepG2 cells. Apoptotic cells were significantly increased on fisetin treatment as observed in morphological evaluations and 4′,6‐diamidino‐2‐phenylindole and Acridine orange staining. Flow cytometry, fluorescence imaging, and 2′, 7′‐dichlorofluorescein diacetate analyses showed an increase in reactive oxygen species (ROS) generation on fisetin treatment. Pretreatment with N‐acetyl cysteine inhibited ROS production and also rescued mitochondrial membrane potential in HepG2 cells. The underlying mechanisms of apoptosis and necroptosis were determined by analysis of their respective signaling molecules using qRT‐PCR and Western blotting. Fisetin showed a marked increase in the expression of TNFα and IKκB with a decrease in NF‐κB, pNF‐κB and pIKκB expression. Fisetin reduced the expression of Bcl2, and elevated levels of Bax, caspase‐3, and PARP and thus induced apoptosis in HepG2 cells. zVAD suppressed the fisetin‐induced expression of caspase‐8, RIPK1, RIPK3, and MLKL as opposed to fisetin treatment. Nec‐1 + fisetin could not completely block necroptosis, which warrants further investigation. Taken together, our findings demonstrate that the fisetin exhibited anti‐proliferative effects on HepG2 cells through apoptosis and necroptosis via multiple signaling pathways. Fiestin has potential as a therapeutic agent against hepatocellular carcinoma.
Simulation of pH level distribution inside a coiled flow inverter for continuous low pH viral inactivation
Authors: David Laura , Waldschmidt Lisa Marie , Lobedann Martin , Schembecker Gerhard 
Published: October 2019

AbstractThe continuous production of monoclonal antibodies (mAbs) with the help of disposable equipment poses one of the future major changes in the pharmaceutical industry. Consequently, continuous viral clearance needs to be developed as well. The coiled flow inverter (CFI) was successfully implemented in the continuous downstream as a residence time module for low pH viral inactivation. As the elution profile of the upstream continuously operated protein A chromatography results in fluctuating pH values, the pH level distribution inside the CFI is highly relevant.This study presents a detailed investigation of pH level distribution inside the CFI at varying inlet conditions with the help of computational fluid dynamics simulation. The simulation model was validated first with the help of experimental data. Afterwards, the model was used for further investigations. It was determined that with a pH sine curve as input, the duration until steady state at the outlet requires two times the minimum residence time of the apparatus. Moreover, it could be observed that the CFI itself offers a progressive dampening effect on the pH level distribution. Afterwards, different forms of the sine curve representing different operation modes of the continuous protein A chromatograph were tested to evaluate this dampening capability. It became clear that the switch time has the highest influence on the resulting pH of the outlet stream and should be considered for process development. Finally, the radial pH profiles at different positions inside the CFI were determined. This once again revealed the high radial mixing capability of the CFI and its influence on the resulting product stream.