bluuebunny/crossref_metadata_2025_split huggingface dataset:
The potential for adaptive water governance on the US–Mexico border: application of the OECD's water governance indicators to the Rio Grande/Bravo basin
Authors: VanNijnatten Debora L. 
Published: October 2020

AbstractDespite decades of political commitments, laws and agreements and significant policy effort, the governance system in the Rio Grande/Bravo basin is not able to meet the water demands generated by a growing region. Long stretches of the river are completely dry for much of the year, and water managers cannot meet full allocations to water users, let alone ensure water quality and quantity for environmental services and sustainability. Both academic scholarship and policy analysis attribute failures such as this to the inability of current water governance regimes to respond to rapidly changing circumstances – to ‘adapt’. The adaptive governance literature calls for resource management regimes that are distributed yet coordinated through polycentric arrangements, as well as flexible; that promote broader engagement and that generate and disseminate knowledge as well as stimulate learning in the face of complexity and uncertainty. This paper reports on the results of qualitative empirical research which applies the OECD's water governance indicators as a diagnostic tool in order to identify the most significant adaptive governance gaps in the transboundary Rio Grande/Bravo basin.
GC-MS/O for the characterization of odours from cheese-production wastewater: A case study
Authors: Hanková M. , Maturová K. , Čížková H. 
Published: October 2020

Abstract
The foul odour of cheese-production wastewater is a common problem in areas surrounding dairy wastewater treatment plants. For successful odour management, a better understanding of the key odorants and how to handle them during wastewater treatment is needed. This paper documents the results of using gas chromatography-mass spectrometry coupled with olfactometry (GC-MS/O) to analyze odours emanating from a possibly overloaded treatment plant in Czechia. Using a DB5 capillary column, 20 compounds were detected and identified, nonanal (FDgeomean 152) and octen-3-ol (FDgeomean 2048) having the most pungent odours.
Protective Effect of Ursolic Acid in Prunella vulgaris L. on LPS-Induced Asthenozoospermia via Bcl-2/Bax Apoptosis Signaling Pathway
Authors: Sun Xiaoyong , Chen Xiaobo , Wang Shengjun , Zhang Jinfeng , Wu Bin , Qin Guozheng 
Published: October 2020

Background:
Asthenozoospermia, also known as lack of sperm motility, accounts for about
27.8% of male infertility as a separate factor, and is often associated with abnormal quantity and morphology
of spermatozoa. Therefore, oligozoospermia has become one of the most important factors affecting
male infertility.

Methods:
Ursolic Acid (UA), also known as wusu acid, is the main active component isolated from
Prunella vulgaris L. and has a variety of pharmacological effects. However, the protective effect of
UA on asthenozoospermia disease has not been reported. In the current study, the purpose of this study
was to investigate the regulatory effect of UA in rats with LPS-induced asthenozoospermia disease. SD
rats were treated with 5 mg/kg LPS, respectively.

Results:
After different concentrations of UA were infused into the stomach of SD rats, microscopy,
flow cytometry, Enzyme-Linked Immunosorbent Assay (ELISA), qRT-PCR and western blot were
used to detect sperm motility, apoptosis, the levels of TNF-α, IL-1β and IL-6, and Bcl-2/Bax apoptosis
pathway related proteins in rat serum and epididymis tissues.

Discussion:
Compared with the normal group, the sperm motility and Bcl-2 level in LPS group decreased
significantly, while the expression of inflammatory factors and Bax proteins increased significantly
(P<0.05). Compared with LPS group, UA intervention group has the opposite result and dose
dependence.

Conclusion:
This study shows that UA can protect LPS-induced asthenozoospermia of rats by increasing
sperm density and motility, regulating Bcl-2/Bax apoptosis pathway and reducing inflammatory
apoptosis response. This experiment provides ideas for improving the clinical treatment of infertile patients
with oligoasthenospermia.
Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells
Authors: Yazici Ayşenur , Marinelli Lisa , Cacciatore Ivana , Emsen Bugrahan , Eusepi Piera , Di Biase Giuseppe , Di Stefano Antonio , Mardinoğlu Adil , Türkez Hasan 
Published: October 2020

Background:
Essential oils are considered as promising sources of novel anticancer
compounds. Carvacrol (CVC), the major constituent of many aromatic plants including oregano
and thymus, is endowed with curative properties on different cancers, including liver, colon, and
lung. Little information is available regarding the potential of CVC for the treatment of brain cancers,
notably Glioblastoma Multiforme (GBM).

Objective:
In this work, we investigated the in vitro effect of CVC codrugs (CVC1-8), synthesized
by direct-coupled co-drug strategies, on human glioblastoma cell line (U87-MG) for the first time.

Methods:
Cell viability was detected by MTT and LDH assays while expression levels of important
genes (such as EGFR, NFKB1A, AKT1, AKT2, and others) associated with GBM and inflammatory
pathways were detected by PCR array.

Results:
Results showed that CVC1-8 codrugs induced cytotoxicity and positive alterations in
molecular responses on U87MG cells. Particularly, important pathways (such as PI3K/PTEN/AKT)
involved in the onset and progression of GBM resulted in modulation by CVC3 and CVC8.

Conclusion:
Our results suggest that CVC3 and CVC8 could be suitable candidates for further investigation
to develop new strategies for the prevention and/or treatment of GBM.
Effectiveness of Mobile Apps to Promote Health and Manage Disease: Systematic Review and Meta-analysis of Randomized Controlled Trials
Authors: Iribarren Sarah J , Akande Tokunbo O , Kamp Kendra J , Barry Dwight , Kader Yazan G , Suelzer Elizabeth 
Published: October 2020

Background
Interventions aimed at modifying behavior for promoting health and disease management are traditionally resource intensive and difficult to scale. Mobile health apps are being used for these purposes; however, their effects on health outcomes have been mixed.

Objective
This study aims to summarize the evidence of rigorously evaluated health-related apps on health outcomes and explore the effects of features present in studies that reported a statistically significant difference in health outcomes.

Methods
A literature search was conducted in 7 databases (MEDLINE, Scopus, PsycINFO, CINAHL, Global Index Medicus, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews). A total of 5 reviewers independently screened and extracted the study characteristics. We used a random-effects model to calculate the pooled effect size estimates for meta-analysis. Sensitivity analysis was conducted based on follow-up time, stand-alone app interventions, level of personalization, and pilot studies. Logistic regression was used to examine the structure of app features.

Results
From the database searches, 8230 records were initially identified. Of these, 172 met the inclusion criteria. Studies were predominantly conducted in high-income countries (164/172, 94.3%). The majority had follow-up periods of 6 months or less (143/172, 83.1%). Over half of the interventions were delivered by a stand-alone app (106/172, 61.6%). Static/one-size-fits-all (97/172, 56.4%) was the most common level of personalization. Intervention frequency was daily or more frequent for the majority of the studies (123/172, 71.5%). A total of 156 studies involving 21,422 participants reported continuous health outcome data. The use of an app to modify behavior (either as a stand-alone or as part of a larger intervention) confers a slight/weak advantage over standard care in health interventions (standardized mean difference=0.38 [95% CI 0.31-0.45]; I2=80%), although heterogeneity was high.

Conclusions
The evidence in the literature demonstrates a steady increase in the rigorous evaluation of apps aimed at modifying behavior to promote health and manage disease. Although the literature is growing, the evidence that apps can improve health outcomes is weak. This finding may reflect the need for improved methodological and evaluative approaches to the development and assessment of health care improvement apps.

Trial Registration
PROSPERO International Prospective Register of Systematic Reviews CRD42018106868; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=106868
The Relationship Between Images Posted by New Mothers on WeChat Moments and Postpartum Depression: Cohort Study
Authors: Zhang Weina , Liu Lu , Cheng Qijin , Chen Yan , Xu Dong , Gong Wenjie 
Published: October 2020

Background
As social media posts reflect users’ emotions, WeChat Moments, the most popular social media platform in China, may offer a glimpse into postpartum depression in the population.

Objective
This study aimed to investigate the features of the images that mothers posted on WeChat Moments after childbirth and to explore the correlation between these features and the mothers' risk of postpartum depression.

Methods
We collected the data of 419 mothers after delivery, including their demographics, factors associated with postpartum depression, and images posted on WeChat Moments. Postpartum depression was measured using the Edinburgh Postnatal Depression Scale. Descriptive analyses were performed to assess the following: content of the images, presence of people, the people’s facial expressions, and whether or not memes were posted on WeChat Moments. Logistic regression analyses were used to identify the image features associated with postpartum depression.

Results
Compared with pictures of other people, we found that pictures of their children comprised the majority (3909/6887, 56.8%) of the pictures posted by the mothers on WeChat Moments. Among the posts showing facial expressions or memes, more positive than negative emotions were expressed. Women who posted selfies during the postpartum period were more likely to have postpartum depression (P=.003; odds ratio 2.27, 95% CI 1.33-3.87).

Conclusions
The vast majority of mothers posted images conveying positive emotions during the postpartum period, but these images may have masked their depression. New mothers who have posted selfies may be at a higher risk of postpartum depression.

Trial Registration
International Clinical Trials Registry Platform ChiCTR-ROC-16009255; http://www.chictr.org.cn/showproj.aspx?proj=15699
Efektivitas Training Fungsi Eksekutif Terkomputerisasi dalam Meningkatkan Kapasitas Fungsi Eksekutif dan Performa Akademik Matematika
Authors: Yusron Isman Rahmani , Kusrohmaniah Sri 
Published: October 2020

Performa bermatematika anak-anak Indonesia, dilaporkan jauh di bawah dari harapan. Terdapat indikasi bahwa fungsi eksekutif berperan dalam performa dan prestasi matematika. Penelitian ini bertujuan menguji efektivitas penggunaan training terkomputerisasi yang mengadopsi paradigma pengukuran fungsi eksekutif, untuk mendongkrak performa bermatematika. Paradigma tugas seperti n-back task, flanker task, go no/go task, numerical-estimation task, dan stroop task, dirangkai menjadi suatu latihan melalui aplikasi OpenSesame®. Kelompok eksperimen (n=32), diberikan 45 menit training selama tujuh hari, dan diberikan tes matematika pada pre dan posttest. Kemudian, dibandingkan dengan kelompok kontrol (n=34) yang juga diberikan pretest dan posttest tanpa diberi perlakuan apapun. Hasil pengujian menunjukkan perbedaan rerata yang signifikan (t=-5,04; p<0,05) pada kelompok eksperimen antara hasil pretest dan posttest. Sedangkan pada kelompok kontrol, tidak ada perbedaan signifikan (t=-1,21; p>0,05). Hasil uji ANAVA terhadap skor kapasitas fungsi eksekutif setiap sesi menunjukkan perbedaan signifikan (F=13,47; p<0,05), dengan plot rerata skor meningkat. Hasil ini menunjukkan bahwa training fungsi eksekutif terkomputerisasi efektif dalam meningkatkan kapasitas fungsi eksekutif dan performa akademik matematika.
Análisis del proyecto constitucional de 2018 en medios cubanos no estatales
Authors: Gallego Ramos José Raúl 
Published: October 2020

El presente artículo describe el debate realizado en 15 medios cubanos no estatales sobre el proyecto constitucional de 2018. Se realizó un análisis de contenido a los 311 textos enfocados en el proyecto constitucional que fueron publicados entre el 13 de agosto y el 15 de noviembre de 2018. Los textos abordaron 121 temáticas específicas, agrupadas en 7 temáticas generales, con destaque para cuestiones relacionadas con derechos ciudadanos y la estructura del Gobierno y el Estado cubanos y el Partido Comunista. Primaron las valoraciones negativas de cuestiones medulares del modelo político cubano, aunque de manera balanceada se reconocieron los aciertos del proyecto constitucional. También destacó el carácter propositivo de muchos textos que sugirieron valiosas incorporaciones al proyecto de Constitución.
Case-Based Clinical Reasoning And Decision Making
Authors: TAŞÇI Ali İhsan , AKDENİZ Esra 
Published: October 2020

Aim: We can define clinical reasoning as the ability to think and decide in clinical processes, which is non-reductive, multidimensional and free from prejudices. Clinical reasoning is a basic competence that a physician should have. In this article, theories about clinical reasoning, stages of clinical reasoning, training and evaluation methods, and the relationship between clinical reasoning and medical malpractice are discussed and related evidence is presented.Methods: The article was prepared by the traditional review methodResults: Non-analytical (system 1), analytical (system 2) thinking and dual process theories are accepted among the theories of how clinical reasoning is realized. Non-analytical thinking is an intuitive thinking that takes place fast and does not require much mental effort. Analytical thinking (system 2 thinking) is established by establishing a cause-effect relationship. In clinical reasoning, the stages of gathering information, forming hypothesis and testing hypothesis constitute a general framework. For clinical reasoning education, frameworks / models for this competence should be determined in educational activities, assessment and evaluation from the first years, and their use should be encouraged. Medical errors and inadequate clinical reasoning processes are related. For this reason, it is important to consider the clinical reasoning insufficiency areas in educational approaches. Clinical reasoning assessments should cover all stages of reasoning. Numerous methods and question / inquiry frameworks have been identified in the evaluation of clinical reasoning. In these, the basic principles are to ask questions that require reasoning with guides structured in accordance with the clinical reasoning stages.Conclusions: Clinical reasoning ability is the basic competence that a physician should have in order to ensure patient safety by reducing medical errors, to reduce unnecessary work and procedures in health, to prevent patient physician disputes and therefore violent events. Learning and assessment activities should be planned using models suitable for clinical reasoning terms and stages.
EMERGING ECONOMETRICS OF BOMB, WAR AND FREE DIRECT INVESTMENTS TO STABILIZE THE SOCIO-ECONOMIC CONDITIONS OF OWN COUNTRY IN GLOBALIZED WORLD
Authors: Kumar Chiranjib 
Published: October 2020

The global economy has been facing a lot of challenges and crisis due to Interlinkage for exchanging goods and services. A race is going on among different nations to become a super powerful country. As a result of which global warming and climate change has been seen throughout the world. A new econometrics has taken over the charge of international politics and that could be seen in the recent developments took place in Korean Peninsula and some part of the world where powerful politicians of the world have been threatening to each other for deep consequences.
The Key Questions are,
Q.1. What happened in the Middle East?
Q.2. What is happening in Syria and others countries?
Ans. The impact would be more transparent and visible in the coming days.
Q.3. What is OBOR (One Belt One Road) of China?
Ans. Imposing their excess burdens on other countries on the name of globalization and peace building and making realize the participating countries that you are under my kindness with liabilities(indirect loan).
The present paper has tried to find out answers of some questions and also suggests solutions at last. Qualitative thinking is always better than quantitative thinking
SHARE AND USE
Authors: Naik Govinda , Manikanta  , Reddy Naram Pooja , Krishna  , Manjunath  
Published: October 2020

Android is one of the most user friendly mobile platforms that have grasped the attention of smart phone users around the globe. According to stats available there are 1.4 billion people who have used Android mobile platform. And this has led to the development of android application exponentially; there are around 2.8 million android applications available in play store. Many of the available application do not fit into low specification smart phones due to some reasons.
Share and Use is an android application that lets you use another smart phones application by your phone without actually installing it on your phone. Share and Use lets user to use application installed on other phones and access applications on their smart phones. Share and Use helps phones with lower specification android phones to use applications that are not be able to install in them.
Dolicomegacolon
Authors: Loaiza Merino Ivan Patricio , Yepez Yerovi Fabián Eduardo , Torres Juan , Salguero Lozada Johana Monserrath 
Published: October 2020

Introducción: El dolicomegacolon de Altura ha sido una entidad poco estudiada a pesar de ser relativamente común en nuestro medio, por lo que también es denominada enfermedad colónica andina, su evolución crónica y su probabilidad de desarrollar complicaciones obstructivas e isquémicas la vuelven una patología de consideración. El vólvulo de sigma es una consecuencia del dolicomegacolon que ocurre en más del 40% de los pacientes que no han sido tratados a tiempo y requieren manejos especiales.
Objetivo: Describir un caso de dolicomegacolon al que se le realiza sigmoidectomia laparoscópica.
Material y métodos: Estudio descriptivo retrospectivo, presentación de caso clínico.
Resultados: Se describe un caso de dolicomegacolon al que se le realiza sigmoidectomia laparoscópica. Se trata de un paciente de 70 años que presentó un caso crónico de estreñimiento y distensión abdominal de más de 20 años de evolución el cual se presentaba con dolor abdominal intenso a repetición por lo que recibió tratamientos farmacológicos, con magaldrato, simeticona, laxantes, entre otras, y modificaciones de dieta, se añadieron alimentos ricos en fibra y fructosa, disminución de carbohidratos, etc. Con el objetico de aliviar el cuadro obstructivo, nunca fue intervenido quirúrgicamente a pesar de que fue hospitalizado en 2 ocasiones, ya que se manejó solamente con enemas evacuantes sin mayor mejoría del cuadro. Debido a que se permitió una progresión tan avanzada de la enfermedad esta se complicó con un vólvulo de sigma que no tenía compromiso vascular, pero necesitaba una resolución quirúrgica, luego del análisis del caso, luego de estudios complementarios diagnósticos y en controles con Medicina Interna se decide programar una cirugía para darle solución definitiva a la patología.
Conclusiones: La principal complicación del dolicomegacolon andino es el vólvulo. El vólvulo por dolicomegacolon andino representa el 54% de las obstrucciones intestinales y el 78% de las enfermedades del colon en la región de los andes. En su mayoría esta complicación requiere una resolución quirúrgica para aliviar los síntomas de los pacientes y evitar el desarrollo de comorbilidades asociadas al tiempo de evolución
HIV-SIDA condición inusual en población pediátrica
Authors: Espín López Valeria Isabel , Barriga Olmedo Johanna Alexandra , Vargas Domínguez Verónica Lissette , Aldas Serrano María Belén , Mora Velasco Christian Alejandro 
Published: October 2020

Introducción: La infección VIH en Pediatría ha experimentado cambios favorables, debido, a que gracias a los protocolos de prevención de la transmisión maternoinfantil, hoy en día, apenas nacen niños infectados. Además, gracias al tratamiento los niños con VIH, se encuentra totalmente integrados en la vida diaria, con una vida plena y sin diferencias con respecto a un niño no VIH.
Objetivo: Describir un caso clínico de VIH-SIDA en edad pediátrica.
Material y métodos: Estudio descriptivo retrospectivo, presentación de caso clínico de VIH-SIDA en edad pediátrica.
Resultados: Pre–escolar, femenino, de 2 años, antecedentes patológicos personales: hospitalización a los 9 meses por Encefalitis viral y Neumonía, HIV no reactivo; al año de edad hospitalizada por Influenza H1N1, Neumonía complicada con derrame pericárdico con HIV no reactivo. Acude a consulta por presentar vesículas en base eritematosa en región frontal, acompañado de prurito, secreción amarrillo purulenta, dolor y edema ocular izquierdo. Se palpa adenopatía de 2 x 1cm en región preauricular izquierda. HIV de cuarta generación tamizaje: reactivo, HIV de cuarta generación confirmatoria por electroquimioluminiscencia de 474.800. Como tratamiento recibió antibioticoterapia intravenosa, antiviral intravenoso y tópico, analgesia intravenosa, antihistamínico vía oral, cursó con remisión a lesiones costrosas a las 24 horas postratamiento y fue referida a Hospital de tercer nivel para iniciar tratamiento antirretroviral.
Conclusiones: En el niño con VIH, se deben realizar los controles de salud inculcándose hábitos saludables en alimentación y ejercicio, así mismo debe recibir el calendario de vacunación completo, estando indicado la vacunación frente a: neumococo, meningococo, papilomavirus, varicela, hepatitis A y gripe estacional. Sin antiretrovirales (ART), la infección VIH produce un deterioro del sistema inmune, de modo que el niño presenta: infecciones bacterianas de repetición, fallo de medro, afectación neurológica y disminución de su esperanza de vida.
Potencial medicinal de Camellia sinensis
Authors: Cáceres Correa Silvia Alexandra , Barba Guzmán Carmen Variña , Carrero Castillo Yenddy Nayghit 
Published: October 2020

Introducción: Desde tiempos inmemoriales se han empleado las plantas como alternativas terapéuticas para el tratamiento de diversas patologías. Camellia sinensis es una planta originaria el sur de China y sudeste de Asia, aunque en la actualidad se cultiva en todo el mundo en las regiones tropicales y suptropicales. Se han descrito diversos efectos del té en la salud, asociados a su principal componente la tannina dentro de los que se mencionan tratamiento contra las enfermedades cardiovasculares, inflamatorias intestinales, neurodegenerativas, cáncer, asma, diabetes, hepatitis entre otras.
Objetivos: La presente revisión tiene como objetivo documentar los efectos sobre la coagulación, fibrinólisis y hemostasia de Camellia sinensis así como su potencial antimicrobiano, a fin de establecer su uso en el tratamiento de diferentes afecciones.
Material y Métodos: Se realizo una revisión sistemática a través de la búsqueda de diversos estudios realizados durante los últimos años en buscadores científicos a través de los operadores booleanos.
Resultados: Se obtuvo un metaanálisis que evidencia el potencial medicinal de la Camellia sinensis.
Conclusiones: Es de suma importancia incentivar el estudio etnobotánico de plantas medicinales con potencial terapéutico y su efecto en diversas patologías humanas como posibles agentes y/o adyuvantes en los tratamientos existentes