bluuebunny/crossref_metadata_2025_split huggingface dataset:
TonB‐dependent uptake of β‐lactam antibiotics in the opportunistic human pathogen Stenotrophomonas maltophilia
Authors: Calvopiña Karina , Dulyayangkul Punyawee , Heesom Kate J. , Avison Matthew B. 
Published: November 2019

AbstractThe β‐lactam antibiotic ceftazidime is one of the handful of drugs with proven clinical efficacy against the important opportunistic human pathogen Stenotrophomonas maltophilia. Here, we show that mutations in the energy transducer TonB, encoded by smlt0009 in S. maltophilia, confer ceftazidime resistance and smlt0009 mutants have reduced uptake of ceftazidime. This breaks the dogma that β‐lactams enter Gram‐negative bacteria only by passive diffusion through outer membrane porins. We also show that ceftazidime‐resistant TonB mutants are cross‐resistant to fluoroquinolone antimicrobials and a siderophore‐conjugated lactivicin antibiotic designed to target TonB‐dependent uptake. This implies that attempts to improve the penetration of antimicrobials into S. maltophilia by conjugating them with TonB substrates will suffer from the fact that β‐lactams and fluoroquinolones coselect resistance to these novel and otherwise promising antimicrobials. Finally, we show that smlt0009 mutants already exist among S. maltophilia clinical isolates and have reduced susceptibility to siderophore‐conjugated lactivicin, despite the in vitro growth impairment seen in smlt0009 mutants selected in the laboratory.
Views on migraine pathophysiology: Where does it start?
Authors: Edvinsson Lars , Haanes Kristian Agmund 
Published: November 2019

AbstractMigraine is a highly prevalent disorder (15.1% worldwide), afflicting up to 3 times more females in the middle ages than men. In most subjects, migraine attacks are sporadic; however, some individuals experience a gradual increase in frequency over time, and up to 1‐2% develop chronic migraine. Although migraine has been known for centuries, the mechanisms still largely remain unknown; two principal sites of origin are still in play: (i) intracranial vasculature and (ii) the origin in central regions such as hypothalamus, with both being suggested to activate the trigeminal vascular system. We share here our views on the pathophysiology of migraine and suggest that it starts in the CNS and involves the brainstem and finally the trigeminovascular system to complete the attacks. The recently developed monoclonal antibodies toward the neuropeptide calcitonin gene‐related peptide (CGRP) and its receptor provide key support for this line of events and are supported by preclinical experiments. The purpose of this review is to discuss our neuroscience perspective on migraine pathophysiology and putatively to serve as stimulus for future in‐depth studies.
Natural Value of Böhler's Angle in Normal Chinese Population
Authors: Ma Zhi‐jian , Bai Li‐ping , Zhang Guang‐ming , Zhang Lian‐bi , Chen Zhong 
Published: November 2019

ObjectiveTo determine the value of Böhler's angle (BA) in a group of Chinese people, analyze possible factors that influence it, and compare BA with that in previous literature.MethodsA total of 143 cases, aged from 4 to 79 years, were enrolled in the study, including 64 males and 79 females (79 left feet and 64 right feet). Radiographs were independently measured by six observers. Age, sex, body side, subtalar joint congruity (STJC), and X‐beam obliquity (TT) were recorded. The database was assessed based on intraobserver agreement, data distribution, the randomness of case selection, and the ratio equality of binomial variables. Then, the normal value of BA was established, as well as the correlation between BA and other parameters.ResultsIn the present study, the interobserver reliability of BA, STJC, and TT was excellent. The BA data revealed a normal distribution, and the randomness of case selection was verified for age, sex, and body side. The ratio of sex and body side was equal. Homogeneity of variance was observed when comparing the value of BA between different groups. The value of BA was 31.6° ± 5.19° (range, 20.08°–47.19°), which was not related to age, sex, body side, and minor X‐ray beam obliquity. BA application was not suitable for individuals younger than 10 years. The mean value of BA in this study was not identical with those in previous reports. This demonstrated that BA varies for different races.ConclusionFor Chinese people, 30° to 33° is recommended as the target value of BA for calcaneal fracture reduction, except in children under 10 years of age.
A case of neonatal pemphigus vulgaris with co‐existing BP180 autoantibodies
Authors: Fenner Justine , Min Michelle S. , Liu Stephanie , Silverberg Nanette 
Published: November 2019

AbstractA male neonate was born with blisters on the trunk to a 37‐year‐old primigravid woman with a past medical history of recurrent, painful, topical steroid‐responsive oral blisters. The diagnosis of neonatal pemphigus was made after the neonate and mother were found to have elevated desmoglein 3 (Dsg3) antibodies in conjunction with histopathologic features of pemphigus vulgaris. Interestingly, both neonate and mother also had elevated levels of BP180 antibodies, classically seen in bullous pemphigoid. This case is unique in that it portrays neonatal pemphigus, an already rare condition, complicated by the presence of BP180 antibodies.
Hot‐water baths, biologicals and re‐curing effects on rhizopus soft rot during sweetpotato packing
Authors: Sweany R. R. , Picha D. H. , Clark C. A. 
Published: November 2019

Rhizopus soft rot (RSR) caused by Rhizopus stolonifer is one of the most devastating postharvest diseases of sweetpotato. It causes greatest losses when sweetpotatoes are removed from storage, washed and packed for marketing. The disease has been managed effectively by prophylactic application of synthetic fungicides on the packing line. However, there is increasing demand for alternative management strategies that do not rely on prophylactic use of synthetic fungicides. While curing immediately after harvest is a standard industry practice, re‐curing after storage is not widely practised for postharvest disease management. In this study, the use of hot‐water baths, biocontrol agents and re‐curing after storage were investigated as potential replacements for synthetic fungicides that are widely used during sweetpotato packing. Hot‐water baths at 52 °C for 10–15 min immediately after inoculation reduced RSR incidence by as much as 75%, but increased susceptibility to post‐treatment Rhizopus infection. The biological control product Bio‐Save® (a.i. Pseudomonas syringae strain ESC‐10), used in conjunction with a 4 min water bath at 52 °C, gave similar protection (1.2% RSR, t = −1.7, P = 0.514) as the industry standard treatment with dicloran. Re‐curing for as little as 4 h after washing roots significantly reduced RSR and deserves further evaluation to optimize conditions and determine its influence on other postharvest diseases.
Self‐report of emotional experience and peer nominations of expressivity: Predictability of change in teacher‐rated social behavior
Authors: Kwon Kyongboon , Teer JaNae E. , Maurice Samuel A. , Matejka Cassandra M. 
Published: November 2019

AbstractWe investigated individual differences in self‐reported emotional experience and peer‐perceived expressivity among children in mid‐ to late‐elementary school years. Specifically, we examined the constructs’ correspondence and temporal stability and also compared the degree to which each predicts change in classroom social behavior over 2 years. Participants were 199 children (Mage = 10 years, Time 1) and their classroom teachers who have participated in two times of assessment. We used self‐report of emotional experience and peer nominations of expressivity regarding happiness, anger, and sadness. Teachers rated children's social skills, externalizing problems, and internalizing problems. The correspondence was generally small in magnitude between self‐reported experience and peer nominations of expressivity. The stability of peer nominations of emotional expressivity was medium and comparable to that of self‐reported experience with the exception of happiness. The predictability of change in social behavior was more robust for peer nominations of expressivity than for self‐reported experience. We discussed the relevance of different dimensions of emotionality as well as informants in understanding the predictability of social behavior from emotionality. We also discussed the role of sociodemographic variables in emotional experience and expressivity and offered practical implications of peer nominations in the assessment of children's emotionality.
Vlogging and the discursive co‐construction of ethnicity and beauty
Authors: Bhatia Aditi 
Published: November 2019

AbstractTaking as its data set beauty tutorials on YouTube, considered to be audio‐visual discursive products that combine speech, body performance, and text (posted comments) to relay specific meanings (Bhatia, 2018), this paper investigates both production of text on part of the sender (vlogger) and interpretation of the text on part of the recipient (viewers) in the joint creation of identity. I analyze the data by employing van Dijk's (2015) socio‐cognitive approach to critical discourse analysis, which emphasizes that the relationship between discourse and society is ‘cognitively mediated’ (p. 64), and aspects of Gee and Green's (1998) MASS System in treatment of discourse as social practice. More specifically, this paper focuses on how British‐Indian vlogger Kaushal discursively constructs the role of expert YouTuber and Indian diaspora in her tutorials to attract a niche viewership within the mass audience of beauty consumers to boost both her unique and conforming identities.
Reviewer Acknowledgements
Authors: Johnson Patricia 
Published: November 2019

Studies in Media and Communication (SMC) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether SMC publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 7, Number 2 Andreas Veglis, Aristotle University of Thessaloniki, GreeceAntonio García Gómez, University of Alcalá de Henares, SpainAslı Sezgin, Osmaniye Korkut Ata University, TurkeyBegoña Montero-Fleta, Universitat Poltècnica de València, SpainBernard Naledzani Rasila, University of Venda, South AfricaCarmen Pérez-Sabater, Universitat Politècnica de València, SpainDiego Santos Vieira de Jesus, International Relations, BrazilImed Ben Labidi, Doha Institute for Graduate Studies, USAJavier Serrano Puche, University of Navarra, SpainJenny-Ann Danell, Umea University, SwedenJoerg Tropp, Pforzheim University, GermanyKunle Olufemi Aramide, The Polytechnic Ibadan, NigeriaMillaray Salas, Pontificia Universidad Católica De Valparaíso, ChileNuran E. Isik, Izmir University of Economics, TurkeyPhilemon Bantimaroudis, University of Cyprus, CyprusRefat Aljumily, Newcastle University, UKShiza Nisar, Lahore School of Economics, PakistanSimone Tosoni, Catholic University of Milan, ItalyWilliam Thomas Howe, University of Oklahoma, USAYoung Joon Lim, University of Texas Rio Grande Valley, USAYuan Gao, Curtin University, Australia Patricia JohnsonEditorial AssistantOn behalf of,The Editorial Board of Studies in Media and CommunicationRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://smc.redfame.com
Oil Pipeline Geohazard Risk Mitigation via On-Line Optical Fiber Strain Monitoring
Authors: Méndez Alexis , Salazar Ferro Andrés 
Published: November 2019

Abstract
Pipelines are naturally vulnerable to operational, environmental and man-made effects such as internal erosion and corrosion; mechanical deformation due to geophysical risks and ground movements. This paper describes the on-line monitoring ofmultiple critical sections ofburied oil pipelines, part of Ecopetrol’s transportation network across the country, which were experiencing mechanical deformations due to local soil and geohazard effects using fiber optic strain sensors. Over 1,000 individual fiber optic Bragg grating (FBG) strain sensors were installed across 72 different sectors dispersed across the Colombian pipeline network. The system has been in service since 2013 and has helped provide early warning on several severe pipeline accumulated strain deformations and imminent ruptures, as well as to understand the mechanical behavior on buried pipelines under diverse soil geohazard conditions.
Risk Control Through Evaluation of Catastrophic Scenarios
Authors: Amórtegui Gil José Vicente 
Published: November 2019

Abstract
In sectors where pipelines cross areas exposed to severe hazards or where the consequences are serious, traditional analyses based on the Risk Analysis Matrix (RAM) do not reflect the effect of the works and actions taken for risk control. That condition induces the idea of ineffectiveness or uselessness of the works and actions taken for protection and reinforcement. In this paper, for those situations it is proposed the analysis of hypothetical scenarios to determine which of them can become catastrophic, in order to assess which situations can trigger a catastrophe, and in consequence to take actions regarding them and thus to avoid the catastrophic situation.
The suggested method consists in proposing scenarios of damages, corresponding an event of loss of product containment of a hydrocarbon transport system. In those scenarios, the following consequences of the oil spill are determined: the behaviour of the product, its route, the site of rupture, the possible threats that affect it, and the triggers of the threatening processes.
Critical or catastrophic scenarios are selected and the chain of events regarding them is determined as detailed as possible. When analysing that chain, it is possible to find actions that may modify it, such as the control of the route so that it does not reach the sensitive elements, the strengthening of the pipeline to bear the hazards, the reinforcement of the ground to prevent the action of the hazards and to avoid that the hazard takes place.
It must be determined how to protect the exposed elements and how to handle the spilled product to avoid the affectation of the elements mentioned above. For this point, it is important to know the infrastructure of the Contingency Plan and therefore to evaluate the possibility of strengthening it.
An Analytical Approach for Pipeline Geohazard Management
Authors: Huisman Otto , Rizkalla Moness , Tindall Matt , Reyes Alejandro , Santana Erika 
Published: November 2019

Abstract
Contamination of waterbodies as a result of hydrocarbon releases is one of the most undesirable events in our industry. Unfortunately, over the past few years, several major events have occurred around the globe, and geohazards have played a major role in many of these. Indeed, Pipeline Geohazard Management is a complex, multi-disciplinary process, heavily dependent on data integration and expert judgment. The current work presents a methodology that allows the identification of critical zones by assessing potential hydrocarbon release mechanisms that could affect waterbodies and adjacent areas, including: channel section pipeline failures, approach slope pipeline failures and spill path effects. The geological model is constructed based on datasets such as a digital elevation model (DEM), surficial geology and route geometry form. Additional datasets can also be derived to represent features such as drainage basins and slopes. The entire framework is being implemented on a data and integrity management platform that not only supports the integration of spatial, geological and general integrity management data (including multiple ILI data sets) but can also execute processes, such as stability analysis, and provide visualizations of results within a GIS (Geographic Information System) environment. Execution of semi-quantitative and quantitative risk assessments is also facilitated, as well as the elaboration of rehabilitation plans. To illustrate the methodology application and the platform capabilities, an anonymized, but real, case study is presented.
A New Approach for the Geotechnical Zoning of the Rights of Way
Authors: Chaves Agudelo Julian , Aristizabal Ceballos Jaime , Motta Tierradentro Carlos , Alvarado Franco Juan 
Published: November 2019

Abstract
Usually, the definition of geotechnically homogeneous zones is established through the analysis of information on a regional (and even national) scale of those characteristics that define the topographic, geological, climatic, and land use conditions by categorizing them and applying algorithms of interaction between these variables. However, in technical literature and in technical reports of state entities that manage natural hazards, new advances are being made in the determination of other aspects or variables that detail the condition of geotechnical susceptibility; at the same time, nowadays there are technological tools for the massive analysis of information and its spatialization. This article presents a new approach to the definition of geotechnically homogeneous zones using these technological tools. A comparison is made against the conventional definition.
Analysis of the Acceleration Transfer in the Unguided Vibratory Finishing Process
Authors: Lachenmaier Maximilian , Ohlert Marius , Trauth Daniel , Bergs Thomas 
Published: November 2019

Abstract
The work bowl acceleration of a vibratory finishing machine is mainly determined by the process input variables, e. g. the mass distribution between the upper and the lower imbalance weights, the offset angle between these imbalance weights and the rotational speed of the imbalance motor. The acceleration of the work bowl has a strong effect on the acceleration of the abrasive media and workpiece within the work bowl and thus on their movement. This movement indirectly determines the contact conditions, contact forces and relative velocities, between the abrasive media and the workpiece. The contact conditions have a strong effect on the material removal rate and the surface roughness of the machined workpieces in a vibratory finishing process. Due to the fact that the contact conditions can hardly be measured during the vibratory finishing process a comprehensive understanding of the transfer behavior of the work bowl acceleration on the acceleration of the abrasive media and the workpiece and thus on the prevailing contact conditions is necessary. Therefore, this publication presents an innovative approach to identify these cause-effect relationships, in order to determine the machining intensity based on the work bowl acceleration as a function of the process input variables. Hence, new measurement systems are presented which enable the determination of the acceleration of the abrasive media and the workpiece as a function of the acceleration of the work bowl of a vibratory finishing machine for the first time. Based on these investigations it is possible to identify significant areas for the work bowl acceleration, as well as for the acceleration of the abrasive media and the workpiece and thus for the contact conditions, contact forces and relative velocities, which can be used for a targeted control of the machining intensity of vibratory finishing processes.
Experimental Investigation of Vibration Assisted Helical Milling of 7075 Aluminum Alloy
Authors: Ali Mariam N. , El-Hofy Hassan 
Published: November 2019

Abstract
Vibration-assisted helical milling (VAHM) is a novel machining process in which an axial ultrasonic vibration is superimposed to the milling cutter. The current work aims to experimentally investigate the influence of applying ultrasonic vibration on the machining performance during helical milling of 7075 aluminum alloy. A full factorial design of experiment is first implemented. Analysis of Variance (ANOVA) is then performed to study the effect of rotational speed (n), tangential feed (Ft), helical pitch (P) and ultrasonic vibration on the process performance. The output response variables considered in this investigation are cutting forces (axial, tangential and radial), torque and hole quality in terms of out-of-roundness, hole size error and surface roughness. The results show that the best cutting conditions to minimize the cutting forces and the diameter deviation are the rotational speed of 5000 rpm, tangential feed of 100 mm/min and helical pitch of 0.1 mm/rev with the assistance of the ultrasonic vibration. The ultrasonic vibration improves the performance of helical milling by decreasing the axial cutting forces.
Real-Time Prognostic and Dynamic Maintenance Window Scheme for Reconfigurable Manufacturing Systems
Authors: Dong Yifan , Xia Tangbin , Xiao Lei , Pan Ershun , Xi Lifeng 
Published: November 2019

Abstract
Real-time condition acquisition and accurate time-to-failure (TTF) prognostic of machines are both crucial in the condition based maintenance (CBM) scheme for a manufacturing system. Most of previous researches considered the degradation process as a population-specific reliability characteristics and ignored the hidden differences among the degradation process of individual machines. Moreover, existing maintenance scheme are mostly focus on the manufacturing system with fixed structure. These proposed maintenance scheme could not be applied for the reconfigurable manufacturing system, which is quite adjustable to the various product order and customer demands in the current market. In this paper, we develop a systematic predictive maintenance (PM) framework including real-time prognostic and dynamic maintenance window (DMW) scheme for reconfigurable manufacturing systems to fill these gaps. We propose a real-time Bayesian updating prognostic model using sensor-based condition information for computing each individual machine’s TTFs, and a dynamic maintenance window scheme for the maintenance work scheduling of a reconfigurable manufacturing system. This enables the real-time prognosis updating, the rapid decision making for reconfigurable manufacturing systems, and the notable maintenance cost reduction.
Conceptualization and Design of a Low-Cost MTConnect-Enabled Refractometer for Coolant Health Monitoring
Authors: Feldhausen Thomas , Hirani Asimm , King Walter , Lynn Roby , Kurfess Thomas 
Published: November 2019

Abstract
Monitoring of the health of water-based coolant used for machining requires measurement of various parameters of the coolant, including refractive index, temperature, pH, and turbidity. One of the primary parameters that is used to determine the concentration of the coolant is the refractive index, which is typically measured manually by an operator at regular intervals during machine operation. This paper describes the conceptualization and preliminary design of a coolant health monitoring system that will automatically measure the refractive index of the coolant and will digitize the resulting measurement for communication to a factory supervisory control and data acquisition (SCADA) system. To enable rapid integration into a factory’s network architecture, the coolant concentration measurement will be transmitted by the monitoring system using the MTConnect format. Having an MTConnect-enabled sensor will allow the data to be remotely aggregated and compared to other machine data to help give a better understanding of overall machine health. The economical approach to its design allows the coolant health monitor to be realizable for both small manufacturing enterprises (SMEs) and large manufacturers alike. This widespread implementation will further benefit industry’s movement toward Internet-of-Things (IoT)-equipped manufacturing facilities.