bluuebunny/crossref_metadata_2025_split huggingface dataset:
A combination of CSP-based method with soft margin SVM classifier and generalized RBF kernel for imagery-based brain computer interface applications
Authors: Hekmatmanesh Amin , Wu Huapeng , Jamaloo Fatemeh , Li Ming , Handroos Heikki 
Published: February 2020

AbstractSeveral methods utilizing common spatial pattern (CSP) algorithm have been presented for improving the identification of imagery movement patterns for brain computer interface applications. The present study focuses on improving a CSP-based algorithm for detecting the motor imagery movement patterns. A discriminative filter bank of CSP method using a discriminative sensitive learning vector quantization (DFBCSP-DSLVQ) system is implemented. Four algorithms are then combined to form three methods for improving the efficiency of the DFBCSP-DSLVQ method, namely the kernel linear discriminant analysis (KLDA), the kernel principal component analysis (KPCA), the soft margin support vector machine (SSVM) classifier and the generalized radial bases functions (GRBF) kernel. The GRBF is used as a kernel for the KLDA, the KPCA feature selection algorithms and the SSVM classifier. In addition, three types of classifiers, namely K-nearest neighbor (K-NN), neural network (NN) and traditional support vector machine (SVM), are employed to evaluate the efficiency of the classifiers. Results show that the best algorithm is the combination of the DFBCSP-DSLVQ method using the SSVM classifier with GRBF kernel (SSVM-GRBF), in which the best average accuracy, attained are 92.70% and 83.21%, respectively. Results of the Repeated Measures ANOVA shows the statistically significant dominance of this method atp< 0.05. The presented algorithms are then compared with the base algorithm of this study i.e. the DFBCSP-DSLVQ with the SVM-RBF classifier. It is concluded that the algorithms, which are based on the SSVM-GRBF classifier and the KLDA with the SSVM-GRBF classifiers give sufficient accuracy and reliable results.
Assessing the construct validity and responsiveness of Preference-Based Measures (PBMs) in cataract surgery patients
Authors: Breheny Katie , Hollingworth William , Kandiyali Rebecca , Dixon Padraig , Loose Abi , Craggs Pippa , Grzeda Mariusz , Sparrow John 
Published: February 2020

Abstract
Purpose
The validity and responsiveness of the EQ-5D-3L in visual conditions has been questioned, inspiring development of a vision ‘bolt-on’ domain (EQ-5D-3L + VIS). Developments in preference-based measures (PBM) also includes the EQ-5D-5L and the ICECAP-O capability wellbeing measure. This study aimed to examine the construct validity and responsiveness of the EQ-5D-3L, EQ-5D-5L, EQ-5D-3L + VIS and ICECAP-O in cataract surgery patients for the first time, to inform choice of PBM for economic evaluation in this population.

Methods
The analyses used data from the UK Predict-CAT cataract surgery cohort study. PBMs and the Cat-PROM5 [a validated measure of cataract quality of life (QOL)] were completed before surgery and 4–8 weeks after. Construct validity was assessed using correlations and known-group differences evaluated using regression. Responsiveness was evaluated using effect sizes and analysis of variance to compare change scores between groups, defined by patient-reported and clinical outcomes.

Results
The sample comprised 1315 patients at baseline. No PBMs were associated with visual acuity and only the ICECAP-O (Spearman’s rs =  − 0.35), EQ-5D-3L + VIS (rs =  − 0.42) and EQ-5D-5L (Value Set for England rs =  − 0.31) correlated at least moderately with the Cat-PROM5. Effect sizes of change were consistently largest for the EQ-5D-3L + VIS (range 0.34–0.41), followed by the ICECAP-O (range 0.20–0.34). Results indicated no improvement in responsiveness using the EQ-5D-5L (range 0.13–0.16) compared to the EQ-5D-3L (range 0.17–0.20).

Conclusions
Whilst no PBMs comprehensively demonstrated evidence of construct validity and responsiveness in cataract surgery patients, the ICECAP-O was the most responsive generic PBM to improvements in QOL. Surprisingly the EQ-5D-5L was not more responsive than the EQ-5D-3L in this setting.
A Numerical Investigation on the Electrochemical Behavior of CaO and Al2O3 in the ESR Slags
Authors: Karimi-Sibaki E. , Kharicha A. , Wu M. , Ludwig A. , Bohacek J. 
Published: February 2020

Abstract
Field structures including electromagnetic, concentration of ions, and flow fields in an ESR-like process composed of a graphite crucible containing a molten slag, air, and an iron electrode are computed. Both CaF2—(mass pct 2) CaO and CaF2—(mass pct 2) Al2O3 slags are examined. Tertiary current distribution is calculated. Therefore, polarization overpotential and Faradic reactions at metal–slag interface are considered using Tafel law, whereas transport of ions in the bulk of slag is determined through Nernst–Planck equations. The main goal is to shed light on the invisible phenomena such as magnetohydrodynamics caused by transport of ions, electrical conductivity of CaF2-based slag using additives (e.g., CaO or Al2O3), and the role of complexation of ions (e.g.,

$$ {\text{AlO}}_{3}^{3 - } $$

AlO

3

3
-

) in the molten slag applied to the ESR. An explanation is given for the observation of higher oxygen content in the metal using Al2O3 than that using equivalent amount of CaO in the CaF2-based slag of a DC-operated ESR.
Systematic review of the effectiveness of self-initiated interventions to decrease pain and sensory disturbances associated with peripheral neuropathy
Authors: Ogle Theodora , Alexander Kimberly , Miaskowski Christine , Yates Patsy 
Published: February 2020

Abstract
Purpose
A small number of studies report that patients with peripheral neuropathy (PN) who engage in activities that promote a sense of personal well-being and provide physical, emotional, or spiritual comfort have a better quality of life and higher levels of adjustment to the changes generated by their illness and accompanying symptoms. This systematic review sought to evaluate the effectiveness of self-management activities that patients with PN initiate themselves to relieve PN symptoms and improve quality of life.

Methods
Search terms were limited to include self-management activities initiated by patients (i.e., activities with no or minimal involvement from clinicians) that aim to provide relief of PN symptoms. Outcomes included in searches were pain, numbness, and tingling, associated with PN and quality of life.

Results
The database searches identified 2979 records, of which 1620 were duplicates. A total of 1322 papers were excluded on the basis of screening the abstract. An additional 21 full text articles were excluded because they did not meet the eligibility criteria. A total of 16 papers were included in the review.

Conclusion
This review identified that a number of self-management strategies that were initiated by patients, including heat, exercise, meditation, and transcutaneous electrical nerve stimulation (TENS) therapy, may reduce self-reported PN symptoms. As the available studies were of low quality, these strategies warrant further investigation with more homogeneous samples, using more rigorously designed trials and larger samples.

Implications for Cancer Survivors
Patients experiencing PN may find a range of self-initiated strategies beneficial in reducing PN symptoms and improving quality of life. However, because of the low quality of the available studies, clinicians need to monitor patients’ responses to determine the effectiveness of these interventions as adjuncts to clinician-initiated interventions.
Comment on ‘Is ‘re-mobilisation’ nature restoration or nature destruction? A commentary’ by I. Delgado-Fernandez, R.G.D. Davidson-Arnott & P.A. Hesp
Authors: Arens Sebastiaan M , de Vries Sierd , Geelen Luc HWT , Ruessink Gerben , van der Hagen Harrie GJM , Groenendijk Dick 
Published: February 2020

AbstractIn their recently published paper, Delgado-Fernandez et al. (2019) critically review the limitations and dangers of the relatively recent shift towards dune rejuvenation management in North-western Europe. We would like to comment on the paper from the Dutch perspective.
Criminal justice, artificial intelligence systems, and human rights
Authors: Završnik Aleš 
Published: February 2020

AbstractThe automation brought about by big data analytics, machine learning and artificial intelligence systems challenges us to reconsider fundamental questions of criminal justice. The article outlines the automation which has taken place in the criminal justice domain and answers the question of what is being automated and who is being replaced thereby. It then analyses encounters between artificial intelligence systems and the law, by considering case law and by analysing some of the human rights affected. The article concludes by offering some thoughts on proposed solutions for remedying the risks posed by artificial intelligence systems in the criminal justice domain.
Psychological, social and biological correlates of body perception disturbance in complex regional pain syndrome
Authors: Schulte-Goecking H. , Azqueta-Gavaldon M. , Storz C. , Woiczinski M. , Fraenkel P. , Leukert J. , Azad S. C. , Kraft E. 
Published: February 2020

AbstractBody Perception Disturbance (BPD) in Complex Regional Pain Syndrome (CRPS) still represents a poorly understood phenomenon. Research has shown that knowledge about changes in body perception can yield relevant information for understanding and treating the disease. This study addressed possible connections between BPD and psychological and social factors, pain intensity, and disease duration. Sixty patients with chronic CRPS Type I of the hand were recruited. Body Perception Disturbance was assessed using the Galer and Jensen Neurobehavioral Questionnaire (GJ) and the BATH CRPS Body Perception Disturbance Scale (BATH). Depression, anxiety, stress, childhood trauma and other life events were assessed using standardized and validated questionnaires. This study found that BPD in CRPS was significantly correlated with measures of depression, anxiety, current stress, quality of life, and pain intensity, but not with stress experienced in the twelve months preceding onset of illness, childhood trauma, or duration of illness. Future research needs to identify which patients are most likely to develop these psychological conditions of CRPS, so that early, preventive intervention is possible. This study establishes a relationship between depression, anxiety, current stress, quality of life, pain intensity, and BPD severity. It also supports literature suggesting that preexisting stress, childhood trauma, and disease duration have no influence on BPD. The findings suggest that there is a bidirectional influence between brain alterations, psychological symptoms, and illness severity.
The role of pathology in sarcoma
Authors: Liegl-Atzwanger Bernadette 
Published: February 2020

SummarySoft tissue sarcomas are exceedingly rare cancers with more than 100 different histiologic subtypes and tremendous morphologic heterogeneity. Next generation sequencing (NGS) techniques have drastically improved our knowledge about these tumours. The possibility to use these techniques routinely changed the diagnostic standards in soft tissue pathology. Within the last few years pathologists were confronted with a growing number of exceedingly rare, partly molecularly defined, tumour entities. The proposed pathologic diagnosis dictates prognosis and treatment. Therefore, specialized soft tissue pathology units with the possibility to include molecular diagnostics into a histopathological report for diagnostic, predictive and prognostic aspects are needed. A second opinion by a soft tissue pathologist, before final treatment decision, should be mandatory to ensure optimal treatment for all patients by a multidisciplinary team in a specialized centre.
Influence of Reaction Time in the Emotional Response of a Companion Robot to a Child’s Aggressive Interaction
Authors: Alhaddad Ahmad Yaser , Cabibihan John-John , Bonarini Andrea 
Published: February 2020

AbstractThe quality of a companion robot’s reaction is important to make it acceptable to the users and to sustain interactions. Furthermore, the robot’s reaction can be used to train socially acceptable behaviors and to develop certain skills in both normally developing children and children with cognitive disabilities. In this study, we investigate the influence of reaction time in the emotional response of a robot when children display aggressive interactions toward it. Different interactions were considered, namely, pickup, shake, drop and throw. The robot produced responses as audible sounds, which were activated at three different reaction times, namely, 0.5 s, 1.0 s, and 1.5 s. The results for one of the tasks that involved shaking the robotic toys produced a significant difference between the timings tested. This could imply that producing a late response to an action (i.e. greater than 1.0 s) could negatively affect the children’s comprehension of the intended message. Furthermore, the response should be comprehensible to provide a clear message to the user. The results imply that the designers of companion robotic toys need to consider an appropriate timing and clear modality for their robots’ responses.
Recent research on factors influencing the quality of frozen seafood
Authors: Nakazawa Naho , Okazaki Emiko 
Published: February 2020

AbstractIn this review, recent findings related to various factors influencing quality properties of fish meat and its products during frozen storage are introduced. Many studies have indicated that protein denaturation is the factor determining the quality of frozen fish meat. Ice crystal size does not necessarily determine the quality of frozen fish meat because the tissue of meat reabsorbs water during the thawing process, unless it has been previously damaged by protein denaturation. However, the effects of ice crystals on the quality of thawed fish meat differ based on the fish species, post-mortem stages, protein denaturation, and processing conditions of the fish meat. In the case of frozen-thawed lightly salted fish meat, salting conditions greatly affect the water holding capacity of muscle and the ice crystal size. Also, in the case of frozen kamaboko, which is denatured protein gel, as the thawed water is not absorbed enough by the protein gel, ice crystal size could be a determining factor of quality. The appropriate freezing and storage conditions required for maintaining quality must be based upon the characteristics of each seafood product.
Accelerating sulfonyl fluoride synthesis through electrochemical oxidative coupling of thiols and potassium fluoride in flow
Authors: Cao Yiran , Adriaenssens Benjamin , de A. Bartolomeu Aloisio , Laudadio Gabriele , de Oliveira Kleber T. , Noël Timothy 
Published: February 2020

AbstractSulfonyl fluorides are valuable synthetic motifs which are currently of high interest due to the popularity of the sulfur (VI) fluoride exchange (SuFEx) click chemistry concept. Herein, we describe a flow chemistry approach to enable their synthesis through an electrochemical oxidative coupling of thiols and potassium fluoride. The reaction can be carried out at room temperature and atmospheric pressure and the yield of the targeted sulfonyl fluoride, by virtue of the short inter-electrode distance between a graphite anode and a stainless-steel cathode, reached up to 92% in only 5 min residence time compared to 6 to 36 h in batch. A diverse set of thiols (7 examples) was subsequently converted in flow. Finally, a fully telescoped process was developed which combines the electrochemical sulfonyl fluoride synthesis with a follow-up SuFEx reaction.
Being an other‐sex crush during early adolescence in India: Investigating socio‐behavioral and psychological concomitants
Authors: Bowker Julie C. , Stotsky Miriam T. , White Hope I. , Kamble Shanmukh V. 
Published: February 2020

ABSTRACTIntroductionAfter years of neglect, there is now strong empirical interest in adolescents' romantic experiences. Most studies, however, focus on adolescents’ romantic relationships in Western societies and fail to consider other‐types of romantic experiences and adolescents who reside in non‐Western societies.MethodsThe present study begins to address these research gaps by examining the social‐behavioral and psychological concomitants of being viewed by many other‐sex peers as a crush, or having high crush status, in a large (N = 445; 56% male; Mage = 13.77 years, SD = 0.43) longitudinal sample of young adolescents in urban India.ResultsUtilizing self‐ and peer‐report data, results provide the first evidence that being viewed by many peers as an other‐sex crush in India is related to some of the same (i.e., physical attractiveness), but also different (i.e., shyness) social‐behavioral characteristics relative to what has been found in studies of young adolescents from the United States. Further analysis revealed new evidence regarding the unique social‐behavioral (i.e., decreased physical aggression) and psychological (i.e., decreased social anxiety) outcomes associated with high crush status in urban India.ConclusionsTaken as a whole, results underscore the importance of considering the larger cultural context in studies of young adolescents’ crush experiences.
C*-algebras of a Cantor system with finitely many minimal subsets: structures, K-theories, and the index map
Authors: BEZUGLYI SERGEY , NIU ZHUANG , SUN WEI 
Published: February 2020

We study homeomorphisms of a Cantor set with $k$ ($k<+\infty$) minimal invariant closed (but not open) subsets; we also study crossed product C*-algebras associated to these Cantor systems and certain of their orbit-cut sub-C*-algebras. In the case where $k\geq 2$, the crossed product C*-algebra is stably finite, has stable rank 2, and has real rank 0 if in addition $(X,\unicode[STIX]{x1D70E})$ is aperiodic. The image of the index map is connected to certain directed graphs arising from the Bratteli–Vershik–Kakutani model of the Cantor system. Using this, it is shown that the ideal of the Bratteli diagram (of the Bratteli–Vershik–Kakutani model) must have at least $k$ vertices at each level, and the image of the index map must consist of infinitesimals.
Tricarboxylic acid cycle dehydrogenases inhibition by naringenin: experimental and molecular modelling evidence
Authors: August Pauline Maciel , Grings Mateus , Grunwald Marcelo Sartori , Zanatta Geancarlo , Stone Vinícius , de Lemos Rodrigues Patricia Idalina , Stocher Daniela Pereira , Moreira José Cláudio Fonseca , Leipnitz Guilhian , Matté Cristiane 
Published: February 2020

AbstractThe study of polyphenols’ effects on health has been gaining attention lately. In addition to reacting with important enzymes, altering the cell metabolism, these substances can present either positive or negative metabolic alterations depending on their consumption levels. Naringenin, a citrus flavonoid, already presents diverse metabolic effects. The objective of this work was to evaluate the effect of maternal naringenin supplementation during pregnancy on the tricarboxylic acid cycle activity in offspring’s cerebellum. Adult female Wistar rats were divided into two groups: (1) vehicle (1 ml/kg by oral administration (p.o.)) or (2) naringenin (50 mg/kg p.o.). The offspring were euthanised at 7th day of life, and the cerebellum was dissected to analyse citrate synthase, isocitrate dehydrogenase (IDH), α-ketoglutarate dehydrogenase (α-KGDH) and malate dehydrogenase (MDH) activities. Molecular docking used SwissDock web server and FORECASTER Suite, and the proposed binding pose image was created on UCSF Chimera. Data were analysed by Student’s t test. Naringenin supplementation during pregnancy significantly inhibited IDH, α-KGDH and MDH activities in offspring’s cerebellum. A similar reduction was observed in vitro, using purified α-KGDH and MDH, subjected to pre-incubation with naringenin. Docking simulations demonstrated that naringenin possibly interacts with dehydrogenases in the substrate and cofactor binding sites, inhibiting their function. Naringenin administration during pregnancy may affect cerebellar development and must be evaluated with caution by pregnant women and their physicians.
Yogurt consumption and colorectal polyps
Authors: Rifkin Samara B. , Giardiello Francis M. , Zhu Xiangzhu , Hylind Linda M. , Ness Reid M. , Drewes Julia L. , Murff Harvey J. , Spence Emma H. , Smalley Walter E. , Gills Joell J. , Mullin Gerard E. , Kafonek David , La Luna Louis , Zheng Wei , Sears Cynthia L. , Shrubsole Martha J. ,   the Biofilm Study Consortium
Published: February 2020

AbstractDiet modifies the risk of colorectal cancer (CRC), and inconclusive evidence suggests that yogurt may protect against CRC. We analysed the data collected from two separate colonoscopy-based case–control studies. The Tennessee Colorectal Polyp Study (TCPS) and Johns Hopkins Biofilm Study included 5446 and 1061 participants, respectively, diagnosed with hyperplastic polyp (HP), sessile serrated polyp, adenomatous polyp (AP) or without any polyps. Multinomial logistic regression models were used to derive OR and 95 % CI to evaluate comparisons between cases and polyp-free controls and case–case comparisons between different polyp types. We evaluated the association between frequency of yogurt intake and probiotic use with the diagnosis of colorectal polyps. In the TCPS, daily yogurt intake v. no/rare intake was associated with decreased odds of HP (OR 0·54; 95 % CI 0·31, 0·95) and weekly yogurt intake was associated with decreased odds of AP among women (OR 0·73; 95 % CI 0·55, 0·98). In the Biofilm Study, both weekly yogurt intake and probiotic use were associated with a non-significant reduction in odds of overall AP (OR 0·75; 95 % CI 0·54, 1·04) and (OR 0·72; 95 % CI 0·49, 1·06) in comparison with no use, respectively. In summary, yogurt intake may be associated with decreased odds of HP and AP and probiotic use may be associated with decreased odds of AP. Further prospective studies are needed to verify these associations.
Effects of standard v. very long Roux limb Roux-en-Y gastric bypass on nutrient status: a 1-year follow-up report from the Dutch Common Channel Trial (DUCATI) Study
Authors: Leeman M. , Gadiot R. P. M. , Wijnand J. M. A. , Birnie E. , Apers J. A. , Biter L. U. , Dunkelgrun M. 
Published: February 2020

AbstractLaparoscopic Roux-en-Y gastric bypass (RYGB) is considered the ‘gold standard’ for surgical treatment of morbid obesity. It is hypothesised that reducing the length of the common limb positively affects the magnitude and preservation of weight loss but may also impose a risk of malnutrition. The aim of this study was to compare patients’ nutrient and vitamin deficiencies in standard RYGB with a very long Roux limb RYGB (VLRL-RYGB). This study was part of the multicentre randomised controlled trial (Dutch Common Channel Trial), including 444 patients undergoing an RYGB or a VLRL-RYGB. Laboratory results, use of multivitamin supplements and reoperations were collected at baseline and 1 year postoperative. Primary outcome measure was nutrient deficiency after 1 year postoperative. Secondary outcome measure was the reoperation rate due to malabsorption. In total, 227 patients underwent RYGB and 196 patients underwent VLRL-RYGB. Most common deficiencies at 1 year postoperative were ferritin (17·2–18·2 %), Fe (23·4–35·6 %), K (7·4–15·2 %), vitamin B12 (9·0–9·9 %) and vitamin D (22·7–34·5 %). Patients undergoing VLRL-RYGB had slightly but significantly lower levels of Ca, Fe and vitamin D compared with those undergoing RYGB at 1 year postoperative, but significantly higher levels of folic acid and Na. Reoperation rates due to malabsorption were not significantly different between RYGB (2/227, 0·9 %) and VLRL-RYGB (7/196, 3·6 %) (P = 0·088). We concluded that patients undergoing VLRL-RYGB had significantly lower levels of Ca, Fe and vitamin D compared with those undergoing RYGB at 1 year postoperative, but higher levels of folic acid and Na. Reoperation rates did not differ. Close monitoring on nutrient deficiencies should be performed in patients undergoing VLRL-RYGB.