bluuebunny/crossref_metadata_2025_split huggingface dataset:
МЕТОДИКА ФОРМИРОВАНИЯ МЕХАНИЗМА УСТОЙЧИВОГО РАЗВИТИЯ ПРОМЫШЛЕННОГО ПРЕДПРИЯТИЯ НА ПРИНЦИПАХ И ИНСТРУМЕНТАХ КОНТРОЛЛИНГА
Authors: Пермовский Анатолий Алексеевич 
Published: December 2024

Целью исследования является структурирование, описание механизма устойчивого развития и актуализация соблюдения принципов концепции устойчивого развития как важного элемента формирования стратегического планирования промышленных предприятий.
Методология исследования. К используемым методам относятся причинно-следственный анализ, моделирование и обобщение.
Результаты исследования заключаются в наращении научного знания в области устойчивого развития промышленных предприятий и, как следствие, реализации технологических, организационных и структурных проектов, ориентированных на аспекты устойчивого развития. Автором популяризируется концепция устойчивого развития как перманентное развитие компании, поддерживающая оптимальный баланс с факторами внешней и внутренней среды. Применение ESG-принципов позволяет предприятиям получать преимущества перед конкурентами, улучшать репутацию, привлекать инвестиции. Наличие и выполнение стратегии устойчивого развития должно стать одной из основных целей современного промышленного предприятия, так как оно служит фундаментом эффективного управления.
Перспективы исследования. Повестка устойчивого развития в России актуальна даже в условиях сложившихся непростых геополитических факторов и санкционных ограничений. Экспортоориентированная страна не может игнорировать общие мировые стандарты и принципы. Соблюдение ESG-факторов на принципах и инструментах контроллинга представляет собой неотъемлемую составляющую эффективной деятельности как отдельного предприятия, так и промышленных отраслей России в целом.
A systematic review on recent advancements in 3D surface imaging and artificial intelligence for enhanced dental research and clinical practice
Authors: Manjunatha Vinayaka Ambujakshi , Parisarla Hima , Parasher Shlagha 
Published: December 2024

Advancements in three-dimensional (3D) surface imaging and artificial intelligence (AI) are transforming dental research and clinical practice by providing high-precision, non-invasive tools for diagnosis, treatment planning, and outcome prediction. Traditional imaging methods, while effective, often lack dimensional detail and involve radiation exposure, whereas 3D imaging and AI offer improved safety and accuracy. This systematic review aims to evaluate the efficacy, safety, and practical applications of 3D surface imaging and AI technologies in dentistry, with a focus on orthodontics, maxillofacial surgery, and diagnostic practices.Following PRISMA guidelines, a comprehensive literature search was conducted across databases including PubMed, Cochrane Library, and Google Scholar. Studies were selected based on criteria such as population, intervention type, and outcome relevance. Data extraction and quality assessment were performed using standardized tools, and bias was evaluated with the Cochrane Risk of Bias Tool for randomized controlled trials and ROBINS-I for non-randomized studies.The review included 50 studies encompassing various imaging technologies (e.g., structured light scanning, laser scanning) and AI applications (e.g., convolutional neural networks). Findings indicate significant improvements in diagnostic accuracy, patient-specific modeling, and clinical workflow efficiency. Benefits include reduced radiation exposure, enhanced diagnostic precision, and increased affordability, although challenges remain in terms of operational complexity, cost, and potential AI biases.3D surface imaging and AI represent substantial advancements in dental practice, enabling precise diagnostics, tailored treatment, and improved patient outcomes. Future research should focus on refining AI algorithms, standardizing protocols, and developing accessible, portable 3D imaging devices to expand these technologies’ reach in clinical settings.
Bacteriological profile of breast abscess and its antimicrobial susceptibility at tertiary care hospital
Authors: Fefar Disha Rameshbhai , Desai Riya Nimeshbhai , Shingala Hitesh Kantilal , Mehta Krunal Dineshbhai 
Published: December 2024

: A breast abscess often arises as a complication of bacterial mastitis, particularly when treatment is either insufficient or delayed. These abscesses are usually caused by pyogenic bacteria. The primary treatment involves draining the abscess, and antibiotics are prescribed based on the results of a culture report.: The present study was conducted to address microbiological profile of breast abscess and elucidates antimicrobial susceptibility of isolates. This retrospective study was conducted at tertiary care hospital, Jamnagar from July 2023 to June 2024. Total 100 suspected breast abscess cases were assessed. Pus aspirates from abscesses received at microbiology laboratory were cultured and examined for bacterial growth by various microbiological methods. After the identification of the bacterial pathogen, antimicrobial susceptibility testing was done by Kirby-Bauer disc diffusion method on Muller Hinton agar according to CLSI guidelines. Majority of cases belonged to lactational group. The most common bacterial isolate was (83.5%), and out of them 41% were methicillin-resistant (MRSA). Others included Enterococcus species and gram-negative organisms like , , , and . isolates (both MSSA and MRSA) showed good sensitivity towards drugs like tetracycline , cotrimoxazole and linezolid. The maximum occurrence (71% cases)of breast abscess was seen in lactating women. was the predominant organism found. For our institute recommended drugs for an initial empirical therapy are amoxycillin-clavulanic acid, erythromycin and clindamycin. Pregnant and lactating mothers should be trained and counselled on breastfeeding and breast hygiene. Following strict infection control practices in maternity wards can help reduce the risk of acquiring infections during the hospital stay.
A retrospective study on antimicrobial resistance pattern of uropathogenic E. coli in rural paediatric population attending tertiary care centre in Tamil Nadu
Authors: Sheriff Riyaz , Shanmugam Priyadarshini , R Alice Peace Selvabai , Jayakaran Jaison , Thayikkannu Ambujavalli Balakrishnan 
Published: December 2024

Urinary tract infections are one of the commonest infections occurring in pediatric population. The diagnosis of UTI is difficult due to lack of proper history and absence of typical clinical symptoms as in the adult population. The most common reasons for development of UTI are the anatomical proximity in female and surface area of the prepuce in male uncircumcised children. The most common bacteria associated with infections are , , , , & . Among the gram-positive organisms, , , , & have been documented to cause infections. : Urine samples processed for culture and sensitivity, from January 2021 to December 2023 from patients ranging from zero days to 18 years were included in the study. Repeat urine samples were excluded from the study. Sample showing no growth or insignificant growth or more than two types of bacterial colonies were excluded from the study. All samples of patients above the age of 18 years were also excluded. Those samples which fit the inclusion criteria were tabulated according to age, gender, bacterial species and antimicrobial resistance. The above data was collected using the ERP software Sage 300. The samples were divided based on the age group of the patients into four groups comprising of Group I: 0 days to 2 years, Group II: 2 to 5years, Group III – 6 to11 years & Group IV: 12 to 18 years. The study revealed a significant prevalence of urinary tract infections (UTIs) in the pediatric population, with being the primary causative agent. The highest incidence was observed in the 0-2 age group, with a notable decline in infections in male children as they aged. Female children, however, exhibited a more persistent infection rate across different age groups. Alarmingly, increasing antibiotic resistance was observed, particularly against ampicillin, cephalosporins, and fluoroquinolones. In contrast, aminoglycosides, carbapenems, nitrofurantoin, and fosfomycin demonstrated higher sensitivity rates, highlighting their potential as effective treatment options. There needs to be a separate antibiotic policy for paediatric patients according to the age group and gender so that age & gender-based antibiotics can be selected for empirical therapy. This will in turn lead to a better antibiotic usage which will be cost effective as well as handle the emerging drug resistant organisms of the Enterobacteriaceae family.
Enterococcal infection rates from various clinical samples and phenotypic characterization of Vancomycin-resistant enterococcus (VRE) at tertiary care hospital
Authors: Baldaniya Neha , Sood Nidhi , Parmar Rosy , Mandalia Asha , Maheta Hemanshi 
Published: December 2024

Enterococci are increasingly prevalent in both community and hospital-acquired infections, posing a significant challenge due to their resistance to common antibiotics, including vancomycin. Given the lack of specific prevalence data at our hospital, we conducted a study to isolate and characterize from various clinical samples and assess their resistance profiles, particularly to vancomycin, to guide more effective treatment strategies and improve patient outcomes.All clinical samples such as blood, urine, pus, sputum, CSF and other fluids from the hospital were processed using standard bacteriological procedures, including Gram staining and culture on selective media. The enterococcal isolates were identified using conventional biochemical tests, including catalase test, bile esculin hydrolysis, and carbohydrate utilization tests. Antimicrobial susceptibility testing was performed according to CLSI guidelines.From a total of 12,013 clinical specimens, 50 enterococcal isolates were recovered. Among these, 34% were from blood, followed by 30% from urine, 16% from pus, 14% from fluids, 4% from sputum, as well as 2% from CSF. A total of 52% of the isolates were from indoor patients, and 62% were from women. faecalis was the second most common species, after . The antibiotic susceptibility pattern demonstrated 100% susceptibility to linezolid. Resistance to vancomycin and teicoplanin was observed in 20% and 28% of isolates, correspondingly, with 70% of isolates exhibiting resistance to both vancomycin and teicoplanin. The present investigation reveals a high rate of VRE (Vancomycin-resistance ) isolates in our hospital, with a majority of isolates showing resistance to both teicoplanin and vancomycin. The situation worsens due to the Van A phenotype and the multidrug resistance these medicines demonstrate, which leaves fewer therapeutic options for the treatment. This highlights how important it is to carry out routine surveillance to quickly identify and manage infections caused by in both hospitals and the community.
Salivary dynamics: Assessing pH, glucose levels, and oral microflora in diabetic and non-diabetic individual
Authors: Mohanty Neeta , Saha Sohini , Mohanty Susant , Sharma Namya , Rath Shakti 
Published: December 2024

: Diabetes significantly impacts oral health, including alterations in the oral microflora. Increased glucose levels in the oral cavity create an environment conducive to the growth of certain pathogenic bacteria, leading to various oral and systemic diseases. These organisms can then move to the bloodstream, causing systemic inflammation and leading to health problems like cardiovascular disease and systemic infections. : This study aimed to compare the salivary pH, glucose concentration, and oral microflora in diabetics and non-diabetics and to correlate that elevated salivary glucose can lead to oral and systemic infections. This single-centre, cross-sectional study involved 25 diabetics and 25 non-diabetics aged 18 years and above. The study duration was 60 days. Saliva samples collected from patients of both groups were subjected to biochemical and microbial analysis. In biochemical analysis, the pH and glucose concentrations were monitored. In microbial analysis, routine and PCR-based assays were used to identify the significant organisms from the saliva samples from both groups. : The average pH (7.028) of the non-diabetic individuals was higher, towards the neutral range; however, in diabetic individuals, the range (6.016) was towards acidic. The salivary glucose estimation results showed that the average glucose concentration in the non-diabetic group was less than in the diabetic group. The oral microbiological profile of diabetic patients differed from those of non-diabetics, where the number of bacterial colonies was significantly higher in diabetic individuals. Notably, the number of dental caries-causing bacteria was 25 in diabetic and 23 in nondiabetic patients. This can be attributed to the reduced pH of the saliva and the elevated glucose level. : The oral microbiological profile of diabetic patients differed from that of non-diabetics, with diabetics having considerably more bacterial colonies. Results suggested that diabetic individuals are at a higher risk of oral and systemic infections. Hence, maintaining balanced glucose levels can help protect oral health by limiting the nutrients available for pathogenic bacteria, reducing inflammation, and supporting immune function.
A retrospective study of thyroid functional status in patients treated with radiation therapy over head and neck region for squamous cell carcinoma of head and neck
Authors: Barman Rina , Sau Sourav , Maiti Pradip Kumar 
Published: December 2024

Head and neck cancer is the sixth most common carcinoma in the world.Management of head neck cancer is either surgery or radiotherapy (RT) for early stage tumour and surgery combined with radiotherapy, radical radiotherapy or concurrent chemoradiotherapy (CCRT) for advanced stages. One of the most common clinical late effects of thyroid gland irradiation in patients exposed to therapeutic doses to the neck is hypothyroidism.To estimate the prevalence of hypothyroidism in post radiation head neck cancer patients where radiation portal included total or most of the thyroid gland and o calculate the Odds ratio for the development of subclinical or clinical hypothyroidism.From February 2018 to May 2019, 102 patients with histopathologically proven advanced (stage III, IV) squamous cell carcinoma of head and neck region (excluding patients with thyroid malignancy and prior neck surgery) who were treated with radical external beam radiotherapy (68-70 Gy) delivered by Cobalt 60 Teletherapy machine with conventional fractionation over head and neck region at least 6 months back were studied.Thyroid function tests (T3, T4, TSH, f-T4) were done at 6 months,9 months and 12 months after completion of radiotherapy.Out of the 102 patients with mean age of 50.9 (±9.4) years, 64 (62.7%) were males and 38 (37.3%) were females. Most common Primary tumour site was larynx (36.1%). CCRT was given to 65.7% of patients and 75.5% of patients had stage-III disease. Two patients were lost to follow-up. Overall, 35% developed hypothyroidism of which 18% were clinical (high TSH, low f-T4) and 17% were sub-clinical hypothyroidism (high TSH, normal f-T4) at one year of follow-up.No significant associations were found with age, gender, stage and addition of chemotherapy. In comparison with control group (patients attending other OPDs, N=200) odds ratio for the development of hypothyroidism was found to be 3.5 (subclinical-4.9, Clinical- 1.9).Hypothyroidism is an under‑recognized morbidity of external beam radiation to the neck. Recognizing hypothyroidism early and treating it prevents associated complications. Hence, thyroid function tests should be done during routine follow up.
Analysis of clinical and histopathological differences between right and left sided colon cancers
Authors: Raina Bawana , Kailu Avantika , Mahajan Chakshu 
Published: December 2024

: Right-sided colon cancer (RCC) and left-sided colon cancer (LCC) exhibit distinct clinicopathological characteristics, which may influence their diagnosis, treatment, and prognosis. Understanding these differences is crucial for optimizing patient care and outcomes.This study aimed to analyse and compare the clinical and histopathological features of RCC and LCC in a cohort of 80 patients, focusing on demographic characteristics, clinical presentation and tumor pathology.:A retrospective analysis was conducted on 80 patients diagnosed with colon cancer, divided equally between RCC (n=40) and LCC (n=40). Data on demographic characteristics, clinical presentation, histologic type, tumor size, histologic grade, tumor stage, lymphovascular invasion, and perineural invasion were collected. Statistical analysis was performed using appropriate tests, with a significance level set at p &#60; 0.05.: The mean age of RCC patients was significantly higher than that of LCC patients (68 ± 8 years vs. 64 ± 7 years, p = 0.02). RCC patients more commonly presented with anemia (50% vs. 20%, p = 0.006) and weight loss (40% vs. 15%, p = 0.01), while LCC patients were more likely to report changes in bowel habits (50% vs. 15%, p = 0.001) and rectal bleeding (40% vs. 10%, p = 0.002). Histologic type distribution was similar between RCC and LCC, with adenocarcinoma being the most common subtype in both groups.RCC tumors were larger on average (6.2 ± 1.4 cm vs. 4.5 ± 1.1 cm, p = 0.001) and more likely to be high-grade (40% vs. 20%, p = 0.04). This study highlights significant differences between RCC and LCC in terms of age, clinical presentation, tumor size, and histologic grade. RCC is associated with older age, larger and higher-grade tumors, and a higher incidence of anemia and weight loss, while LCC more frequently presents with changes in bowel habits and rectal bleeding.
Malignant granular cell tumor presenting at unusual site with rare histomorphology
Authors: Mahawar Shruti , Aparajita Anoja , Das Kanhu Charan 
Published: December 2024

The granular cell tumor (GCT) is are benign soft tissue tumor of neuroectodermal differentiation. Its likelihood of malignant transformation is bare minimal, and it seldom involves the anal canal. Herein, we report a case of anal canal with unusual histomorphology too. This report highlights the anomalous nature and site of the tumor, along with its peculiar histology. It also focuses on enhancing diagnostic awareness regarding the entity.
Alveolar soft part sarcoma with neural differentiation and aberrant TLE1 expression: A case report
Authors: Gupta Maydhaavi , Neeravari Ashalatha , Chandran Nirmala , Biligi Dayananda S 
Published: December 2024

Alveolar soft part sarcoma (ASPS) is a rare soft tissue tumor of uncertain histogenesis. It occurs most commonly in deep soft tissues of the lower extremities. Relevant histomorphology and diffuse and strong immunoreactivity of TFE3 has been included in essential diagnostic criteria by WHO Soft tissue and Bone tumors, 5th edition.A 35 years female presented with recurrent painless posterior right thigh mass which progressed to a size of 15x15cm in 6 months. MRI of the swelling showed T1 isointense and T2 hetrointense lesion with multiple flow voids and few non enhancing areas suggestive of necrosis. Fine needle aspiration cytology showed tight clusters of round to oval tumor cells with moderate cytoplasm. Sections from the cell block revealed tumor cells arranged in an organoid pattern. Individual cells showed a round to oval nucleus with powdery chromatin and abundant eosinophilic to clear cytoplasm. Diagnosis of undifferentiated sarcoma was made. Histopathological examination of the excised lesion showed round to oval shaped cells arranged in nests and alveolar pattern. Individual cells showed mild degree of atypia with a vesicular nucleus, moderate eosinophilic cytoplasm and distinct cell borders. Increased mitoses, prominent vascularity, extensive areas of necrosis and hemorrhage were seen. Immunohistochemistry (IHC) for TFE3, TLE1, synaptophysin and BCL2 was positive and it was negative for pan cytokeratin and S100. Periodic acid‐Schiff stain for intracytoplasmic crystalline structures was negative. Based on the histomorphology and IHC, diagnosis of ASPS was made showing neural differentiation and abberent TLE1 expression. Further studies were suggested for confirmation of the diagnosis.Accurate diagnosis of ASPS requires trained pathologists and molecular testing to lead the treatment accordingly. This case is presented owing to its overlapping histomorphological and immunohistochemical findings.
Case report of cytological findings of secretory carcinoma of breast in a 12-year-old girl
Authors: Dhiman Itisha , Jain Chetna 
Published: December 2024

Secretory carcinoma of breast (SCB) is a rare form of breast cancer. It is the most commonly seen in children as primary breast cancer. It is seen more commonly in women as compared to men. These tumours were initially seen in children. Many studies have shown that these cancers can occur in adults as well. In this case report, a young (12) year old female patient presented with left sided breast lump. Patient was referred for ultrasound which revealed a benign well circumscribed lesion.Patient was referred from surgical OPD to department of pathology where she underwent fine needle aspiration cytology (FNAC). Based on cytological findings a provisional diagnosis of secretory carcinoma was made which was confirmed on histopathology. Despite having lower incidence rates these malignant neoplasms should be kept as an important differential in young patients.
Agriculture Drone-A Boon Technology for Foliar Nutrition to Enhance Productivity of Blackgram (Vigna mungo)
Authors: Hemalatha M. , Joseph M. , Vinitha N. , Sowmiya S. , Babu R. Santhosh 
Published: December 2024

Background: The current study aimed to evaluate the effect of foliar nutrition of TNAU pulse wonder and polyfeed using an agricultural drone in comparsion with hand spray on black gram growth and yield efficiency. Methods: The field experiment conducted during the summer of 2023 at the VOC Agricultural College and Research Institute, Tamil Nadu Agricultural University, Killikulam. A randomized block design of eight treatments and three replications was used to set up the experiment. The treatments included drone spray with two different concentration of TNAU pulse wonder and Poly feed individually at the rate of 1.0% and 2.0%). Similarly manual spraying of the same product at 1.0% and 2.0% were performed. Result: The results revealed that drone spray of 2% TNAU pulse wonder with spray fluid of 75 L ha-1 using atomizer nozzle recorded higher plant dry matter production (3952 kg ha-1), more LAI (3.54), higher grain (725 kg ha -1) and haulm yield (2935 kg ha -1), with the net return of 25335 Rs.ha-1 and B:C ratio of Rs.2.20 per rupee invested. it was followed by application of Poly feed 2.0% through drone. Manual spray of both TNAU pulse wonder and Poly feed were underperformed in blackgram. Hence, it is concluded that application of 2% TNAU pulse wonder at 30 and 45 DAS through drone could be a viable technology to improve the growth and yield of black gram.