bluuebunny/crossref_metadata_2025_split huggingface dataset:
Salmonella-Infected Aortic Aneurysm: Investigating Pathogenesis Using Salmonella Serotypes
Authors: CHU CHISHIH , WONG MIN YI , CHIU CHENG-HSUN , TSENG YUAN-HSI , CHEN CHYI-LIANG , HUANG YAO-KUANG 
Published: December 2019

Abstract

Salmonella infection is most common in patients with infected aortic aneurysm, especially in Asia. When the aortic wall is heavily atherosclerotic, the intima is vulnerable to invasion by Salmonella, leading to the development of infected aortic aneurysm. By using THP-1 macrophage-derived foam cells to mimic atherosclerosis, we investigated the role of three Salmonella enterica serotypes – Typhimurium, Enteritidis, and Choleraesuis – in foam cell autophagy and inflammasome formation. Herein, we provide possible pathogenesis of Salmonella-associated infected aortic aneurysms. Three S. enterica serotypes with or without virulence plasmid were studied. Through Western blotting, we investigated cell autophagy induction and inflammasome formation in Salmonella-infected THP-1 macrophage-derived foam cells, detected CD36 expression after Salmonella infection through flow cytometry, and measured interleukin (IL)-1β, IL-12, and interferon (IFN)-α levels through enzyme-linked immunosorbent assay. At 0.5 h after infection, plasmid-bearing S. Enteritidis OU7130 induced the highest foam cell autophagy – significantly higher than that induced by plasmid-less OU7067. However, plasmid-bearing S. Choleraesuis induced less foam cell autophagy than did its plasmid-less strain. In foam cells, plasmid-less Salmonella infection (particularly S. Choleraesuis OU7266 infection) led to higher CD36 expression than did plasmid-bearing strains infection. OU7130 and OU7266 infection induced the highest IL-1β secretion. OU7067-infected foam cells secreted the highest IL-12p35 level. Plasmid-bearing S. Typhimurium OU5045 induced a higher IFN-α level than did other Salmonella serotypes. Salmonella serotypes are correlated with foam cell autophagy and IL-1β secretion. Salmonella may affect the course of foam cells formation, or even aortic aneurysm, through autophagy.
Product marketing strategy of Kapal Api Group uses SWOT Analysis
Authors: Septiani Fauziah , Astria Kenny 
Published: December 2019

Fastrata buana corporation was founded in 1992 in Jakarta. The fastrata buana handles the sale and product distribution of the kapal api group to ensure delivery to customer. Fastrata buana is the largest distribution company in Indonesia With branch and distribution point in Sumatra, Java, Bali, kalimantan, sulawesi and even Papua.The research aims to see what is a marketing strategy of the company's products. By doing SWOT analysis, counting the IFAS and EFAS get recapitulation S-W = a score of 1.5 and O-T = a score of 1,25.It shows that the company's strategy lies within the quadrant 1. Based on analysis of the internal strategy factors that can be seen in the diagram of the SWOT analysis, where the kopi kapal api position is in quadrant 1 that indicates the SO strategy in the SWOT matrix, which is aggressive strategy.An aggressive strategy is one that uses all the power to seize the opportunity.the strategy is one which gives benefit because having opportunity and power to be used improving Fastrata buana corporation.
Ameliorative potential of Anacyclus pyrethrum extract in generalized seizures in rat: Possible cholinergic mediated mechanism
Authors: Bezza Kenza , Gabbas Zineb El , Laadraoui Jawad , Laaradia Mehdi Ait , Oufquir Sara , Chait Abderrahman 
Published: December 2019

The present study evaluates the anticonvulsant activity of the roots of Anacyclus pyrethrum using pilocarpine-induced experimental model of epilepsy in rat, and to determine its possible anticonvulsant mechanism. Ethanol extract (200 and 400 mg/kg) or alkylamides (25 and 50 mg/kg) was administered orally 45 min before the injection of pilocarpine-induced (400 mg/kg) seizures. The possible anticonvulsant mechanism was investigated by testing the effect of atropine (2 mL/kg) and scopolamine (1 mg/kg). The scoring of seizure severity, seizures time latency, duration of total seizures and percentage of mortality protection were recorded. Ethanol extract and alkylamides prolonged the time of onset seizure and decreased the duration of seizures compared to control group (p<0.001). The seizure protection was 100%. The co-administered of ethanol extract of A. pyrethrum and alkylamides with atropine completely abolished the pilocarpine-induced seizures.
Video Clip of Methodology:
Anticonvulsant effect: 6 min 7 sec: Full Screen Alternate
Antidepressant activity of Citrus limetta leaves in mice using battery of behavior models modulating via serotonergic systems
Authors: Kaur Jaspreet , Bhatia Manisha , Nain Parminder 
Published: December 2019

The methanolic extract of Citrus limetta leaves was estimated in the present study for antidepressant activity. This activity was evaluated by using the rat behavioral model i.e. forced swimming and tail suspension model for 14 days, with estimation of neurotransmitters in animals brain. The sedative effect was evaluated by actophotometer. The extract (200 mg/kg) administered orally showed significant (p<0.05) decrease in immobility time against the standard drug fluoxetine (20 mg/kg, i.p), and imipramine (15 mg/kg, i.p.) respectively but no significant reduction was found in the locomotor activity against diazepam (2 mg/kg, i.p.). In depression, the brain reflected low monoamines level like release of norepinephrine, dopamine and serotonin but 14 days after successive administration of the extract, their levels were significantly increased. In conclusion, C. limetta showed significant antidepressant activity.
Video Clip of Methodology:
Forced swimming test: 6 min 17 sec: Full Screen Alternate
FORMULATION OF OINTMENT OF ANTIBACTERY ETHANOL EXTRACT OF TORCH GINGER (Etlingera elatior) AGAINST BACTERIA STAPHYLOCOCCUS AUREUS
Authors: Pulungan Ainil Fithri , Sitepu Debi Dinha Octora , Sinaga Devi Mariana 
Published: December 2019

One of the causes of infection was bacteria, such as Staphylococcus aureus. Torch ginger has been widely used to treat dwaseases caused by bacteria. Torch ginger has been studied to have antibacterial activity against Staphylococcus aureus bacteria. The purpose of thwas study was to formulate an ointment preparation of ethanol extract of torch ginger and to see if the ointment preparations had antibacterial activity against Staphylococcus aureus bacteria. The research method used in thwas research was experimental True, covering the stages: making of ethanol extract of kecombrang flower with maceration method using 96% ethanol solvent, ointment formulation made with ointment base: vaseline, adeps lanae, and propylene glycol. Made in three concentrations of extracts namely: F I with 100 mg, F II with 200 mg, and F III with 300 mg. Furthermore, the evaluation of the preparation of evaluation of physical stability and homogeneity, and test of antibacterial activity against Staphylococcus aureus bacteria with diffusion method to use Kirby odor dwasc paper. The results showed that the ointment had good physical stability and homogeneity for 30 days of storage at room temperature. The antibacterial activity test of the ointment shows that the inhibitory diameter F I has an average of 16.45 mm, F II has an average of 18.60 mm and F III has an average of 21.12 mm. Based on the results obtained it can be concluded that the preparation of the ethanol extract of torch ginger has an inhibitory power to Staphylococcus aureus bacteria. In the next research was expected to pay attention to the growing area of ​​torch ginger and to compare the antibacterial activity between petal flowers and flower seeds using Staphylococcus aureus bacteria.
PENGARUH PENYULUHAN KESEHATAN MODEL PEER GROUP TERHADAP PENGETAHUAN DAN SIKAP REMAJA TENTANG TUBERKULOSIS PARU
Authors: Purba Rentawati , Ferabetty Yusni 
Published: December 2019

Peer groups are teenagers who are equal to the same age and maturity level as well as a place to socialize. One of the problem in adolescence is the lack of knowledge and attitude towards pulmonary TB disease. Purpose of this research to know influence of health counseling peer group model to knowledge and attitude of adolescent about pulmonary TB, type of quasi experimental research, using a comparison group given intervention with non- intervention. This research process has been carried out in april- june 2017 at YP Senior High School Singosari Deli Tua Regency Deli Serdang by method simple random sampling. The number of samples is 76 (38 respondents of intervention group and 38 respondents of non-intervention group). The result showed there was a significant difference (p<0,05) the average value of knowledge and attitudes of adolescents in the intervention and non-intervention groups. This conclusion shows that there is influence of health counseling peer group model to knowledge and attitude of adolescent about pulmonary TB at YP Senior High School Singosari Deli Tua Regency DeliSerdang.
Kemampuan Numerik Siswa Pesisir SMP Negeri Di Kabupaten Wakatobi
Authors: Halyadin Halyadin , Bey Anwar , Kadir Kadir , Samparadja Hafiludin 
Published: December 2019

Penelitian ini bertujuan untuk mendeskripsikan: (1) kemampuan numerik siswa pesisir SMP Negeri di Kabupaten Wakatobi & (2) perbandingan kemampuan numerik siswa pesisir SMP Negeri pada tiap pulau yang ada di Kabupaten Wakatobi. Populasi penelitian ini adalah siswa kelas VIII SMP Negeri di Kabupaten Wakatobi. Teknik pengambilan sampel dalam penelitian ini menggunakan sampel total. Teknik pengumpulan data dilakukan dengan pemberian tes kemampuan numerik (TKN) berbentuk pilihan ganda. Hasil penelitian ini menunjukkan bahwa kemampuan numerik siswa pesisir SMP Negeri di Kabupaten Wakatobi sangat rendah dengan rata-rata 29,85. Rata-rata Kemampuan numerik siswa pesisir SMP Negeri di Kabupaten Wakatobi berurutan adalah pulau Wangi-wangi 29,34, pulau Kaledupa 24,94 , pulau Tomia 35,24, & pulau Binongko 29,27.
Analisis Number Sense Ditinjau dari Gaya Kognitif Reflektif-Impulsif
Authors: Fitri Laylatul , Rachmadwati Lely Putri Riska , Ayati Julia Putri Riska , Muliawati Novita Eka 
Published: December 2019

Penelitian ini bertujuan untuk mendeskripsikan 1) Number sense siswa ditinjau dari gaya kognitif reflektif; dan 2) Number sense siswa ditinjau dari gaya kognitif impulsif. Jenis penelitian yang digunakan pada penelitian ini adalah penelitian kualitatif dengan instrumen penelitian berupa tes MFFT, soal tes number sense dan wawancara. Pemberian tes MFFT bertujuan untuk mengetahui siswa mana yang memiliki gaya kognitif reflektif dan mana siswa yang memiliki gaya kognitif impulsif. Tes MFFT diberikan pada siswa kelas X TKR 2 SMK Negeri 2 Tulungagung dengan siswa sejumlah 36 siswa. Tes number sense diberikan kepada 2 sampel yang telah terpilih berdasarkan gaya kognitif. Hasil penelitian ini menunjukkan bahwa siswa yang memiliki gaya kognitif reflektif menjawab lebih lama dibandingkan siswa dengan gaya kognitif impulsif, memiliki jawaban yang lebih tepat dibandingkan siswa bergaya kognitif impulsif , dan memiliki alasan sendiri terhadap jawaban dibandingkan siswa dengan gaya kognitif impulsif. Kemampuan number sense siswa dengan gaya kognitif reflektif lebih bagus dibandingkan siswa dengan gaya kognitif impulsif.
Pengaruh Model PBL Dengan Pendekatan Saintifik Terhadap Kemampuan CPS Ditinjau Dari Disposisi Matematis Siswa
Authors: Mariana Irma , Fahinu Fahinu , Ruslan Ruslan 
Published: December 2019

Penelitian ini bertujuan untuk mengetahui apakah terdapat peningkatan kemampuan creative problem solving siswa dengan menerapkan model PBL dengan pendekatan Saintifik, dan untuk mengetahui apakah terdapat pengaruh penerapan model PBL dengan pendekatan Saintifik terhadap kemampuan creative problem solving siswa ditinjau dari disposisi matematis siswa. desain penelitian ini yaitu pretest-posttest control group design. Sampel dalam penelitian ini berjumlah 60 siswa dan menggunakan teknik pengambilan sampel purposive sampling. instrumen penelitian yang digunakan, yaitu tes kemampuan creative problem solving dan angket disposisi matematis siswa. hasil analisis data baik statistik deskriptif maupun inferensial menunjukkan bahwa peningkatan kemampuan CPS siswa yang diajar dengan model PBL menggunakan Pendekatan Saintifik lebih tinggi dibanding siswa yang diajar dengan model pembelajaran langsung. Berdasarkan analisis inferensial, menunjukkan bahwa adanya pengaruh PBL dengan Pendekatan Saintifik terhadap kemampuan CPS siswa ditinjau dari disposisi matematis
Pengaruh Pendekatan Open ended Dan Pendekatan Problem posing Terhadap Peningkatan Kemampuan Berpikir Kreatif Matematika Siswa SMP Ditinjau Dari Gaya Kognitif
Authors: Purnadewi Novi , Anggo Mustamin , Baharuddin Baharuddin 
Published: December 2019

Penelitian ini merupakan penelitian eksperimen dengan tujuan untuk mengkaji dan menganalisis : (1) Perbedaan pengaruh pendekatan open ended dan pendekatan problem posing terhadap peningkatan kemampuan berpikir kreatif matematik siswa dengan gaya kognitif reflektif; dan (2) Perbedaan pengaruh pendekatan open ended pendekatan problem posing terhadap peningkatan kemampuan berpikir kreatif matematik siswa dengan gaya kognitif impulsif. Poopulasi dalam penelitian ini adalah seluruh siswa kelas VII SMPN 1 Konawe Selatan sebanyak 10 kelas. Pengambilan sampel kelas dilakukan dengan menggunakan dua teknik, yaitu purposive sampling. Sampel penelitian sebanyak 47 siswa. Pengambilan data dilakukan dengan cara memberi tes kemampuan berpikir kreatif matematika siswa sebelum dan setelah diberikan perlakuan, serta diberi gaya kognitif. Hasil penelitian ini adalah: (1) Tidak terdapat perbedaan pengaruh yang signifikan pendekatan open ended dan pendekatan problem posing terhadap peningkatan kemampuan berpikir kreatif matematik siswa dengan gaya kognitif reflektif; dan (2)Tidak terdapat perbedaan pengaruh yang signifikan pendekatan open ended pendekatan problem posing terhadap peningkatan kemampuan berpikir kreatif matematik siswa dengan gaya kognitif impulsif
Analisis Kemampuan Pemahaman Konsep Matematis Siswa Kelas VIII SMP Negeri 17 Kendari
Authors: Fajar Ayu Putri , Kodirun Kodirun , Suhar Suhar , Arapu La 
Published: December 2019

Tujuan penelitian ini adalah untuk menganalisis kemampuan pemahaman konsep matematis siswa. Penelitian ini adalah penelitian deskriptif eksploratif. Strategi yang digunakan adalah deskriptif kualitatif. Penelitian ini dilaksanakan di SMP Negeri 17 Kendari Tahun Ajaran 2017/2018 pada kelas VIII.7. Sumber data penelitian ini adalah hasil tes dan hasil wawancara. Hasil penelitian ini menunjukkan bahwa pemahaman konsep matematis siswa dengan kategori tingi sebanyak 3%, kategori sedang sebanyak 10%, dan kategori rendah sebanyak 87%. Hasil penelitian ini juga menunjukkan bahwa kinerja siswa dari masing-masing kategori adalah sebagai berikut: (a) siswa pada kategori tinggi dapat mengerjakan 6 butir soal atau menguasai 6 indikator kemampuan pemahaman konsep matematis; (b) siswa pada kategori sedang dapat mengerjakan 6 butir soal atau menguasai 6 indikator kemampuan pemahaman konsep matematis; dan (c) siswa pada kategori rendah dapat mengerjakan 4 butir soal atau menguasai 4 indikator kemampuan pemahaman konsep matematis
Studi Implementasi Kurikulum 2013 Dalam Program Pembelajaran Di TK Dharma Wanita Propinsi Bengkulu
Authors: Nasirun H. M. , Yulidesni Yulidesni , Indrawati Indrawati 
Published: December 2019

Tujuan penelitian adalah memperoleh gambaran kemampuan guru-guru TK Dharma Wanita Propinsi Bengkulu dalam penyusunan program pembelajaran berupa: Rencana Pelaksanaan Pembelajaran (RPPH) Kurikulum 2013. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian deskriptif kuantitatif. Populasi dalam penelitian ini adalah guru-guru TK Dharma Wanita Propinsi Bengkulu. Sampel penelitian adalah sampel total atau sampel populasi yaitu semua guru (12 orang) guru TK Dharma Wanita Propinsi Bengkulu, karena jumlah populasi kurang dari seratus. Hasil penelitian yaitu penyusunan program pembelajaran berupa: Rencana Pelaksanaan Pembelajaran Harian (RPPH) yang disusun oleh guru TK Dharma Wanita Propinsi Bengkulu dalam kategori cukup baik, namun ada beberapa modifikasi disesuaikan lingkungan belajar anak. Rekomnedasi penelitian ini yaitu dalam penyusunan program pembelajaran lebih disesuaikan dengan pedoman kurikulum 2013 dan pelaksanaan pendekatan pembelajaran sentra sesuai dengan pijakan-pijakan (empat pijakan) dalam pembelajaran sentra.Kata kunci: Guru, Pembelajaran Perangkat, Kurikulum 2013
Deskripsi Pola Asuh Orangtua Yang Bekerja Pada Anak Usia Dini Di TK Tunas Makartikota Kendari
Authors: Pahenra Pahenra , Salwiah Salwiah , Taslim Nining R 
Published: December 2019

Tujuan dari penelitian ini yaitu untuk mendeskripsikan pola asuh yang digunakan orang tua yang bekerja pada anak di TK Tunas Makarti Kota Kendari. Subjek dalam penelitian ini meliputi 18 responden yakni orangtua anak didik di TK Tunas Makarti Kota Kendari. Penelitian ini menggunakan metode kualitatif yaitu suatu pendekatan penelitian yang dihasilkan data deskriptif. Berdasarkan hasil temuan yang diperoleh dalam penelitian ini menunjukkan bahwa pola asuh yang diterapkan orang tua yang bekerja pada anak di TK Tunas Makarti Kota Kendari ternyata opsi jawaban yang diberikan seluruh responden adalah relatif sama masing-masing menggambarkan pola asuh otoriter 30%, pola asuh demokratis 55% dan pola asuh permisif 15%.Kata Kunci: Anak Usia Dini, Orang Tua, Pola Asuh.
Hacia una historia de los críticos practicantes argentinos: el caso de Eduardo Mallea
Authors: Sánchez López Pablo 
Published: December 2019

En este artículo se estudian los dos ensayos fundamentales en los que Eduardo Mallea expone su poética (Notas de un novelista y Poderío de la novela) y se analizan las prioridades literarias del novelista argentino, con sus consecuencias ideológicas. En esos textos, Mallea repasa algunas de las opcionesy categorías literarias más comunes a su época y perfila su posición en el campo literario argentino, a partir de sus tesis idealistas, metafísicas y políticamente conservadoras. Destacan especialmente sus respuestas a cuestiones como la fama del existencialismo, la necesidad del compromiso político o el dilema entre nacionalismo y universalismo en la literatura.
María Albergamo, editora. La transparencia engaña
Authors: Lagarda López Czarina 
Published: December 2019

En el año 2013, entre el 22 y el 24 de julio, se llevó a cabo un ciclo de conferencias titulado ¿Transparencia?, dirigido por Jorge Lozano, como parte de los Cursos de Verano de la Complutense, en San Lorenzo de El Escorial. De dichas conferencias, en 2014 se publicó La transparencia engaña. Este ciclo de conferencias emerge después de una serie de investigaciones semióticas realizadas por el Grupo de Estudios de Semiótica de la Cultura (GESC) a raíz del surgimiento y operatividad de WikiLeaks y su impacto en la cultura y en la manera en la que se utiliza la información y la confidencialidad, entre otros. Las conferencias fueron dictadas por algunos miembros de la agrupación, así como por otros invitados, especialistas en distintas áreas, tales como el periodismo, el derecho, la sociología o la semiótica.
Methodical approach to the assessment of the educational migration environment of the population of the Carpathian region
Authors: Semiv Lyubov 
Published: December 2019

The role and importance of the educational migration environment in activating migration movements of the population is described. The main components of the educational migration environment of the population are identified, and their features are outlined. Indicators have been proposed and the conditions for the formation of the educational migration environment of the population have been determined. It is proved that «freedom of knowledge movement» motivates students, teachers and researchers to combine educational and research activities with future employment abroad. The processes of educational migration in the form of cross-border education and academic mobility are presented. The concept of educational migration environment is defined and five main components of its formation are described: quantitative measurement of educational migration potential; quality of the academic environment; motivational conditions; opportunities for universities and industry collaboration in research; institutional conditions in the educational sphere. The list of indicators offered by the Ukrainian statistics is provided for quantitative representation of each component of the educational migration. Based on the method of multidimensional (cluster) analysis, the regional index of formation of educational migration environment is calculated. Using this method allows to move from the assessment of educational migration environment on 28 indicators to the construction of one synthetic indicator. Application of methodical approach allows to see the place of the region by the important parameters of development of the environment of educational migration of the population, to evaluate the attractiveness, opportunities and threats of formation of this environment in the regional dimension. It is proved that the «most favorable» environment in the Carpathian region has the Lviv region (4th place in Ukraine). Other regions of the Ukrainian Carpathians occupy in the ranking the lower places: respectively Ivano-Frankivsk (15th place), Chernivtsi (21st place), Transcarpathian region (24th place).
Studying the Effect of Implement of Two Plowing Depths and Manure Mixing with Soil on the Soil Moisture Content
Authors: Adday Shaker H. , Hemeed Kawther A. , Al-faris Murtadha A. 
Published: December 2019

A field experiment was carried out in silty clay soil at Agricultural Research Station of Garmat Ali in order to study the effect of the plowing depths and manure application on soil moisture content at different soil depths (0-10 (d1), 10-20 (d2), 20-30 (d3), 30-40 (d4), 40-50 (d5) and 50-60 cm (d6)) and two periods (after plowing and after harvesting the sunflower crop). The experiment was conducted using an implement of plowing and manure mixing with soil, which consists of two main parts (two moldboard plows and two subsoilers).The implement was designed and manufactured in the Agriculture machines and Equipment Department in 2015. The treatments used in the study were included two levels of manure application (0 and 45.5 ton ha-1) and two plowing depths of moldboard plow (M) with three plowing depths of subsoiler (S). They were 20 cm of moldboard plow with 20, 30 and 40 cm of subsoiler (M20S20, M20S30 and M20S40), and 30 cm of moldboard plow with 10, 20 and 30 cm of subsoiler (M30S10, M30S20 and M30S30). The results showed that the soil moisture content (MC) was significantly decreased with increasing the plowing depths by the moldboard plows and subsoilers especially after soil plowing. While, the MC significantly increased with increasing the soil depth after the plowing and after harvesting the crop. In contrast, mixing the manure with soil at level 45.5 ton ha-1 by the manufactured implement increased the soil moisture content by 10.73% after the plowing and by 2.33% after the harvesting the sunflower crop compared with untreated soil with manure.