bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of relief and residual low back pain after discectomy in patients with lumbar disc herniation: analysis using a detailed visual analogue scale
Authors: Takahashi Hiroshi , Aoki Yasuchika , Inoue Masahiro , Saito Junya , Nakajima Arata , Sonobe Masato , Akatsu Yorikazu , Koyama Keita , Shiga Yasuhiro , Inage Kazuhide , Eguchi Yawara , Orita Sumihisa , Maki Satoshi , Furuya Takeo , Akazawa Tsutomu , Abe Tetsuya , Funayama Toru , Noguchi Hiroshi , Miura Kousei , Mataki Kentaro , Shibao Yosuke , Eto Fumihiko , Kono Mamoru , Koda Masao , Yamazaki Masashi , Ohtori Seiji , Nakagawa Koichi 
Published: December 2020

Abstract
Background: Several authors have reported favorable results in low back pain (LBP) for patients with lumbar disc herniation (LDH) treated with discectomy. However, detailed changes over time in the characteristics and location of LBP before and after discectomy for LDH remain unclear. To clarify these points, we conducted an observational study to determine the detailed characteristics and location of LBP before and after discectomy for LDH, using a detailed visual analog scale (VAS) bilaterally.Methods: We included 65 patients with LDH treated by discectomy in this study. A detailed VAS for LBP was administered with the patient under 3 different conditions: in motion, standing, and sitting. Bilateral VAS was also administered (affected versus opposite side) for LBP, lower extremity pain (LEP), and lower extremity numbness (LEN). The Oswestry Disability Index (ODI) was used to quantify clinical status. Changes over time in these VAS and ODI were investigated. Pfirrmann grading and Modic change as seen by magnetic resonance imaging (MRI) were reviewed before and 1 year after discectomy to determine disc and endplate condition.Results: Before surgery, LBP on the affected side while the patients were in motion was significantly higher than LBP while they were sitting. This increased LBP on the affected side in motion was improved significantly after discectomy. By contrast, the residual LBP while sitting at 1 year after surgery was significantly higher than the LBP while they were in motion or standing. At 1 year following discectomy, residual LBP while sitting was significantly greater in cases showing changes in Pfirrmann grade or Modic type.Conclusions: Improvement of LBP on the affected side while the patient is in motion suggests that radicular LBP is improved following discectomy by nerve root decompression. Furthermore, that residual LBP is found while the patient is sitting is reflective of the load and pressure put on the disc and endplate.
Anastrozole and Levonorgrestrel-Releasing Intrauterine Device in the Treatment of Endometriosis: A Randomized Clinical Trial.
Authors: Acién Pedro , Velasco Irene , Acién Maribel 
Published: December 2020

Abstract
Background: To study the effectiveness of an aromatase inhibitor (Anastrozole) associated to levonorgestrel-releasing intrauterine device (LNG-IUD, Mirena®) in the treatment of endometriosis.Methods: Prospective, randomized clinical trial. Setting: University Hospital (single center). Elegibility criteria: Endometriomas >3×4 cm, CA-125>35 U/mL and endometriosis symptoms. Patients: Thirty-one women randomized to anastrozole+Mirena®+Conservative Surgery(CS) (n=8), anastrozole+Mirena®+transvaginal ultrasound-guided puncture-aspiration (TUGPA) (n=7), Mirena®+CS (n=9), or Mirena®+TUGPA (n=7). Interventions: Anastrozole 1 mg/day and/or only Mirena® for 6 months; CS (ovarian and fertility-sparing) or TUGPA of endometriomas one month after starting medical treatment. Main Outcome Measures: Visual analogic scale for symptoms, CA-125 levels, ultrasound findings of endometriomas and recurrences. Results: A significant improvement in symptoms during the treatment (difference of 43%, 95% CI 29.9-56.2) occurred, which was maintained at 1 and 2 years. It was more significant in patients treated with anastrozole (51%, 95% CI 33.3-68.7). For CA-125, the most significant decrease was observed without anastrozole (73.8%, 95% CI 64.2-83.4 vs. 53.8%, 95% CI 25.7-81.6 under Mirena®+anastrozole). After CS for endometriosis, a reduction of findings of endometriomas and long-term recurrences occurred, with or without anastrozole. At 4,2±1,7 years (95% CI 3,57-4,85), 88% of the patients who underwent CS were asymptomatic, without medication or reoperation, compared to only 21% if TUGPA was performed, with or without anastrozole (p=0.019). Conclusions: Dosing anastrozole for 6 months, starting one month before CS of endometriosis, reduces more significantly the painful symptoms and delays recurrences, but has no other significant advantages over the single insertion of LNG-IUD (Mirena®) during the same time. Anastrozole and/or only Mirena® associated with TUGPA are not effective.
The systemic review of subgroup analysis on the incidence of acute kidney injury(AKI) in patients with COVID-19
Authors: Xu Zhenjian , Tang Ying , Huang Qiuyan , Fu Sha , Li Xiaomei , Lin Baojuan , Xu Anping , Chen Junzhe 
Published: December 2020

Abstract
Background: Acute kidney injury (AKI) occurs among patients with Coronavirus disease-19 (COVID-19) and has also been proven to be associated with in-hospital mortality. Remdesivir has been authorized for the treatment of COVID-19 patients. We conducted a systematic review to evaluate the incidence of AKI in hospitalized COVID-19 patients. The incidence of AKI in different subgroups was also investigated. Method: A thorough search was carried out to find relevant studies in PubMed, Web of Science, medRxiv and EMBASE from 1 Jan 2020 until 1 June 2020. All systemic reviews of proportions were performed using the meta package for R project (4.0.1).Results: A total of 16199 COVID-19 patients were included in our systematic review. The pooled estimated incidence of AKI in all hospitalized COVID-19 patients was 10.0% (95% CI: 7.0-12.0%). The pooled estimated need for continuous renal replacement therapy (CRRT) in COVID-19 patients was 4% (95% CI: 3-6%). According to our subgroup analysis, the incidence of AKI could be associated with the age, disease severity and the ethnicity of the patients. The incidence of AKI in hospitalized COVID-19 patients being treated with remdesivir was 7% (95% CI: 3-13%) in a total of 5 studies.Conclusion: We found that AKI was not rare in hospitalized COVID-19 patients. The incidence of AKI could be associated with age, disease severity and ethnicity. Remdesivir probably not induced AKI in COVID-19 patients. Our systemic review provides evidence for future studies that AKI might be closely associated with SARS-CoV-2 infection.
Community stakeholder preferences for evidence-based practice implementation strategies in behavioral health: A best-worst scaling choice experiment
Authors: Williams Nathaniel , Candon Molly , Stewart Rebecca , Byeon Y. Vivian , Bewtra Meenakshi , Buttenheim Alison , Zentgraf Kelly , Comeau Carrie , Shoyinka Sosunmolu , Beidas Rinad S. 
Published: December 2020

Abstract
Background: Community behavioral health clinicians, supervisors, and administrators play an essential role in implementing new psychosocial evidence-based practices (EBP) for patients receiving psychiatric care; however, little is known about these stakeholders’ values and preferences for implementation strategies that support EBP use, nor how best to elicit, quantify, or segment their preferences. This study sought to quantify these stakeholders’ preferences for implementation strategies and to identify segments of stakeholders with distinct preferences using a rigorous choice experiment method called best-worst scaling. Methods: A total of 240 clinicians, 74 clinical supervisors, and 29 administrators employed within clinics delivering publicly-funded behavioral health services in a large metropolitan behavioral health system participated in a best-worst scaling choice experiment. Participants evaluated 14 implementation strategies developed through extensive elicitation and pilot work within the target system. Preference weights were generated for each strategy using hierarchical Bayesian estimation. Latent class analysis identified segments of stakeholders with unique preference profiles. Results: On average, stakeholders preferred two strategies significantly more than all others—compensation for use of EBP per session and compensation for preparation time to use the EBP (P<.05); two strategies were preferred significantly less than all others—performance feedback via email and performance feedback via leaderboard (P<.05). However, latent class analysis identified four distinct segments of stakeholders with unique preferences: Segment 1 (n = 121, 35%) strongly preferred financial incentives over all other approaches and included more administrators; Segment 2 (n = 80, 23%) preferred technology-based strategies and was younger, on average; Segment 3 (n = 52, 15%) preferred an improved waiting room to enhance client readiness, strongly disliked any type of clinical consultation, and had the lowest participation in local EBP training initiatives; Segment 4 (n = 90, 26%) strongly preferred clinical consultation strategies and included more clinicians in substance use clinics. Conclusions: The presence of four heterogeneous subpopulations within this large group of clinicians, supervisors, and administrators suggests optimal implementation may be achieved through targeted strategies derived via elicitation of stakeholder preferences. Best-worst scaling is a feasible and rigorous method for eliciting stakeholders’ implementation preferences and identifying subpopulations with unique preferences in behavioral health settings.
Knowledge, Attitude, And Perception of Oral and Maxillofacial Surgery Specialty Amongst Healthcare Professionals, and the General Public from a Gulf Cooperation Council (GCC) Country
Authors: Kamal Mohammad , Abdulwahab Mohammad , Al-Zaid Ahmed 
Published: December 2020

Abstract
Background: Oral and maxillofacial surgery specialty has grown rapidly in Kuwait in recent years. However, the general public and healthcare professionals remain unaware of its expanding scope of practice. The aim of the study is to assess public and professional (dental and medical) perception of the oral and maxillofacial surgical specialty in Kuwait.Methods: This is a cross-sectional study evaluating responses of dental professionals, medical professionals, and general public in Kuwait toward the oral and maxillofacial surgical specialty using a previously validated survey instrument with 100 participants in each group. Participants were asked to choose the most appropriate specialist to treat certain procedures across 4 disciplines: reconstruction, trauma, pathology, and cosmetic. Statistical comparison was conducted between dentists and medical doctors using Fisher’s exact test with a p-value of < 0.05. Results: Disparities were noted each group’s responses. Oral and maxillofacial surgery was preferred overall for most clinical scenarios in trauma (p < 0.001), pathology (p < 0.001), and reconstructive surgery (p < 0.001). Plastic surgery was preferred for cosmetic surgeries (p < 0.001). Conclusions: This study indicates the need to increase awareness especially towards cosmetic surgery procedures, and conduct health campaigns regarding oral and maxillofacial surgery among healthcare professionals, especially medical doctors, and the general public.
Epidemiological profile of Plasmodium ovale spp. imported from Africa to Anhui Province, China, 2012 – 2019
Authors: Zhang Tao , Wang Shuqi , Wang Duoquan , Auburn Sarah , Lu Shenning , Xu Xian , Jiang Jingjing , Lyu Xiaofeng , Yu Chen , Tian Cuicui , Li Shizhu , Li Weidong 
Published: December 2020

Abstract
BackgroundAlthough autochthonous malaria cases are no longer reported in Anhui Province, China, imported malaria has become a major health concern. The proportion of reported malaria cases caused by Plasmodium ovale spp. increased to levels higher than expected during 2012 to 2019, and showed two peaks, 19.69 % in 2015 and 19.35 % in 2018.MethodsA case-based retrospective study was performed using data collected from the China Information System for Disease Control and Prevention (CISDCP) and Information System for Parasitic Disease Control and Prevention (ISPDCP) from 2012 to 2019 to assess the trends and differences between Plasmodium ovale curtisi (P. o. curtisi) and Plasmodium ovale wallikeri (P. o. wallikeri). Epidemiological characteristics were analyzed using descriptive statistics.ResultsP. ovale curtisi and P. ovale wallikeri were found to simultaneously circulate in 14 African countries. Among 128 patients infected with P. ovale spp., the proportion of co-infection cases was 10.16%. Six cases of co-infection with P. ovale spp. and P. falciparum were noted, each presenting with two clinical attacks (the first attack was due to P. falciparum and the second was due to P. ovale spp.) at different intervals. Accurate identification of the infecting species was achieved among only 20.00% of cases of P. ovale spp. infection. At the reporting units, 32.17% and 6.96% of cases of P. ovale spp. infection were misdiagnosed as P. vivax and P. falciparum infections, respectively. ConclusionThe present results indicate that the potential of P. ovale spp. to co-infect with other Plasmodium species has been previously underestimated, as is the incidence of P. ovale spp. in countries where malaria is endemic. P. o. curtisi may have a long latency period of >3 years and potentially cause residual foci, thus posing challenges to the elimination of malaria in P. ovale spp.-endemic areas. Considering the low rate of species identification, more sensitive point-of-care detection methods need to be developed for P. ovale spp. and introduced in non-endemic areas.
Association of depression symptom severity with short-term risk of an initial hospital encounter in adults with major depressive disorder
Authors: Voelker Jennifer , Wang Kun , Tang Wenze , He Jinghua , Daly Ella , Pericone Christopher D , Sheehan John J 
Published: December 2020

Abstract
Background: Despite the availability of pharmacologic and nonpharmacologic treatment options, depression continues to be one of the leading causes of disability worldwide. This study evaluated whether depression symptom severity, as measured by PHQ-9 score, of patients diagnosed with MDD is associated with short-term risk of a hospital encounter (ER visit or inpatient stay). Methods: Adults with ≥1 PHQ-9 assessment in an outpatient setting (index date) and ≥1 MDD diagnosis within 6 months prior were included from the de-identified Optum Electronic Health Record database (April 2016-June 2019). Patients were categorized by depression symptom severity based on PHQ-9 scores obtained by natural language processing. Crude rates, adjusted absolute risks, and adjusted relative risks of all-cause and MDD-related hospital encounters within 30 days following assessment of depression severity were determined.Results: The study population consisted of 280 145 patients with MDD and ≥1 PHQ-9 assessment in an outpatient setting. Based on PHQ-9 scores, 26.9% of patients were categorized as having none/minimal depression symptom severity, 16.4% as mild, 24.7% as moderate, 19.6% as moderately severe, and 12.5% as severe. Among patients with none/minimal, mild, moderate, moderately severe, and severe depression, the adjusted absolute short-term risks of an initial all-cause hospital encounter were 4.1%, 4.4%, 4.8%, 5.6%, and 6.5%, respectively; MDD-related hospital encounter adjusted absolute risks were 0.8%, 1.0%, 1.3%, 1.6%, and 2.1%, respectively. Compared to patients with none/minimal depression symptom severity, the adjusted relative risks of an all-cause hospital encounter were 1.60 (95% CI 1.50-1.70) for those with severe, 1.36 (1.29-1.44) for those with moderately severe, 1.18 (1.12-1.25) for those with moderate, and 1.07 (1.00-1.13) for those with mild depression symptom severity. Conclusions: These study findings indicate that depression symptom severity is a key driver of short-term risk of hospital encounters, emphasizing the need for timely interventions that can ameliorate depression symptom severity.
Three-dimensional analysis of the root canal preparation with Reciproc Blue®, WaveOne Gold® and XP EndoShaper®. A new method in vivo
Authors: Caviedes-Bucheli Javier , Rios-Osorio Nestor , Usme Diana , Jimenez Cristian , Pinzon Adriana , Rincón Jorge , Azuero-Holguin María M , Zubizarreta-Macho Alvaro , Gomez-Sosa Jose F , Munoz Hugo R 
Published: December 2020

Abstract
Background: The purpose of this study was to evaluate the changes in canal volume after root canal preparation in vivo with 3 different single-file techniques (Reciproc-Blue®, WaveOne-Gold® and XP-EndoShaper®), with a new method using CBCT and 3D reconstruction. Methods: In this prospective study, thirty human lower premolars from healthy patients were used, in which extraction was indicated for orthodontic reasons. All the teeth used were caries- and restoration-free with complete root development, without signs of periodontal disease or traumatic occlusion, and with only one straight canal (up to 25º curvature). Teeth were randomly divided into three different groups: Reciproc-Blue, WaveOne-Gold and XP-EndoShaper. CBCT scans before root canal preparation were used to create a 3D reconstruction with RHINOCEROS 5.0 software to assess the initial canal volume, and then compared with 3D reconstructions after canal preparation to measure the increase in canal volume. Student’s t test for paired data were used to determine statistically significant differences between the before and after canal volumes. Anova test was used to determine statistically significant differences in the percentage of canal volume increase between the groups and Tukey's post-hoc test were used to paired comparison.Results: Reciproc-Blue showed the higher increase in canal volume, followed by WaveOne-Gold and XP-EndoShaper (p = 0.003). XP-EndoShaper did not show a statistically significant increase in canal volume after root canal preparation (p = 0.06).Conclusion: With this model, Reciproc-Blue showed higher increase in root canal volume, followed by WaveOne-Gold, while XP-EndoShaper did not significantly increase root canal volume during preparation.
FENOMENA DAKWAH EKS-HTI PASCA DIBUBARKAN
Authors: Fitriyana Siti Nur 
Published: December 2020

<p><em>This paper talking about phenomenon </em><em>of </em><em>e</em><em>x</em><em>-HTI as forbidden mass organization that </em><em>is </em><em>khilafah ideological</em><em>ly</em><em>. </em><em>I</em><em>ts existence in </em><em>I</em><em>ndonesia </em><em>is </em><em>still developed throu</em><em>g</em><em>h all media, print media and new media. </em><em>Print media (bulletin)</em><em> that shaded </em><em>by ex-</em><em>HTI </em><em>is subscribed</em><em> by the community. This </em><em>is proven by the</em><em> total production </em><em>of </em><em>print media </em><em>(bulletin) </em><em>to reach 10.000 eksemplar for distributed in </em><em>I</em><em>ndonesia and then which is no less important </em><em>is</em><em> </em><em>use </em><em>of </em><em>new media to show dakwah </em><em>of ex-</em><em>HTI related to khilafah still </em><em>working </em><em>massive</em><em>ly</em><em>. </em><em>T</em><em>his could </em><em>be </em><em>proven by many post</em><em>s</em><em> on each </em><em>social media </em><em>account, that is to reach </em><em>849 posts</em><em>. </em><em>Both</em><em> media discuss about </em><em>the</em><em> khilafah. The results </em><em>of this </em><em>research show</em><em>s</em><em> that all media shaded</em><em> by</em><em> </em><em>ex-</em><em>HTI change</em><em>s</em><em> </em><em>the </em><em>movement name become GP (Gerakan Pembebasan), BMI (Back To Muslim Identity), and Muslimah News Id. Technique data collection </em><em>uses</em><em> documentation and interview. </em><em>T</em><em>his research concludes that dakwah</em><em> activities</em><em> </em><em>of </em><em>ex-HTI about khilafah are massive and structured. </em><em>This is seen from social media </em><em>account managed </em><em>by ex-</em><em>HTI</em><em> that is </em><em> still post</em><em>ing the</em><em> content of khilafah which are expeted to be enforced. </em></p><p> </p>
Technique and Methodology for Objective Evaluation of Borrowings in Academic Texts
Authors: Avdeeva N. V. , Ivanova E. N. 
Published: December 2020

Purpose. To provide a detailed justification of the methodological principles, guided by the specialists of the “Antiplagiat.RSL” project when conducting an independent assessment of the originality of scientific texts.Materials and methods. The implementation of these principles is demonstrated with the examples from the practice of tests. The proposed material based on more than ten years of experience of plagiarism – test practice, will give authors and administrators of scientific institutions a clearer idea of the procedure and requirements for academic texts.Results. The automated verification of academic texts for plagiarism has become commonplace, which affects all levels - from writing graduate qualification papers to defending doctoral dissertations, publishing monographs and textbooks. There is a wide range of software specially designed for comparing texts and identifying both distinct overlapping text fragments and paraphrased ones. At the same time, everyone who has come across the verification process understands that it is impossible to rely solely on the quantitative indicators presented in the system report. Evaluation of plagiarism-test results is an area where one has to deal with different, sometimes not entirely correct, understanding of the originality of scientific texts.The Russian State Library (RSL) is a national repository and, what is even more important - it remains independent from the academic institutional milieu. The article describes essential principles of the plagiarism tests, carried out at the RSL, which are based on the organizational legitimacy, identification of individual motivation and compliance with the actual normative regulation. Methodology of the tests founds on the five key principles: objectivity, confidentiality, consistency, specificity and complexity.In addition, certain issues of an objective evaluation of plagiarism are considered in order to draw attention to the fact that independent (delegated) verification of scientific texts is one of the components of the process of supporting academic integrity in modern conditions of dissemination and reproduction of information.Conclusion. A detailed check of the texts for plagiarism allows you to make corrections, modify the texts, and eliminate shortcomings caused by the author’s carelessness or negligence. At the same time, deliberate plagiarism even if it may seem insignificant, is the most serious misconduct from the point of view of scientific ethics, and institutional control in this area is necessary.