bluuebunny/crossref_metadata_2025_split huggingface dataset:
Refractodensimetric method for determining the volume fraction of ethyl alcohol in wines and winy beverages
Authors: Timofeev R. G. 
Published: November 2020

The tabular functional dependence of the ethyl alcohol content in liquid products of winemaking on the density and readings of refractometer sugar scale based on the processing of the measurement data of the refractive index and density of the model solutions and samples of wine products, as well as the paralleling determination of the volume fraction of ethyl alcohol by the method certified in winemaking according to GOST 32095-2013 was obtained. The established dependence was the basis for development of a non-destructive express method of determining the volume fraction of ethyl alcohol for wines and wine beverages prepared using products of winemaking, based on the changes in the density and index of refraction of liquid media. The use of bilinear interpolation methods made it possible to create a clear algorithm of actions for processing the measurement data, ensuring the sufficient relevance and unambiguity in determining the volume fraction of ethyl alcohol based on refractometry and densimetry data. Metrological certification of the method has been carried out. The method can be the basis for development of a regulatory document prescribing its use in the wine industry, as well as a technical task for realization of a portable device for determining the volume fraction of ethyl alcohol in liquid products of winemaking, based on the joint measurement of the indexes of refraction and density of the liquid.
Intensification of kvas biotechnology using non-traditional raw materials
Authors: Korotkikh E. A. , Novikova I. V. , Agafonov G. V. , Korotkikh N. V. , Krivanosov I. N. 
Published: November 2020

In the production of beverages of incomplete alcoholic and lactic acid fermentation, it is important to use non-traditional raw materials that have advantages over well-known analogues. Of particular interest in the production of fermented beverages is the use of malt extract prepared from triticalic malt. Serum and products derived from it are biologically complete, have dietary and medicinal properties. To achieve this goal accomplished objectives: to assess the quality and applicability of triticale malt extract for kvass production; explore the possibility of using whey as a processing aid in the production of kvass on the basis of triticale malt extract; to choose a combination of microorganisms to obtain a mixed leaven with the best biotechnological properties; conduct a comparative analysis of the duration of fermentation samples of kvas wort. The most intensive decrease in the dry matter content was observed in the experimental sample of leavened wort prepared on the basis of malt triticalic extract with the use of whey and combined sourdough from dry baking yeast of the brand "SAF-Moment" of the species Saccharomyces cerevisiae and lactic acid bacteria L. lactis, L. cremoris, L. diacetylactis, Str. Thermophilus. The duration of fermentation of leavened wort in the test sample was 10 hours, which is 6–8 hours less than the traditional technology. As a result of this work, the possibility of using triticalic malt extract for the production of kvass was proved. According to the main physical and chemical parameters, triticale malt extract is not inferior to traditional raw materials. The possibility of using whey as a technological additive for fermentation of leavened wort based on triticalic malt extract is investigated. The composition of leavened wort and a combination of microorganisms were selected to produce a combined starter culture with the best biotechnological properties. A comparative analysis of the duration of fermentation of samples of leavened wort is carried out.
Development of a functional product for the prevention of iodine deficiency
Authors: Antipova L. V. , Daryin A. O. 
Published: November 2020

Iodine belongs to the most important elements that are responsible for the full working condition of the body. Iodine deficiency is a very acute problem, its elimination is an important task of the world communities, reflected in the Doctrine of Food security of the Russian Federation, regional target programs of Russia. In the modern world, the proposed measure for the prevention of iodine deficiency is the consumption of iodized salt and some foods containing an inorganic form of iodine, or the use of a variety of biologically active additives. However, according to the observed statistics of diseases that are associated with a lack of iodine, the presented measures are not very effective. The article presents studies of the process of bioconversion of inorganic iodine into organic – bioavailable, capable of reaching the target organ, for example, during the germination of lentil grains in the appropriate nutrient medium. The possibility of obtaining an organic form of iodine from sprouted lentils in an iodized medium with subsequent production of food products, such as vegetable milk, is proved. The organoleptic, physico-chemical parameters of the milk obtained, as well as vitamin and amino acid compositions that increase the nutritional and biological value of the product were studied, the safety indicators were analyzed and meet the requirements for use in food systems. In the course of the work carried out, we obtained a product with a balanced composition of nutrients for the human body. These developments open up prospects for the creation of functional products for functional purposes with a bioavailable form of iodine.
Analysis of the chemical composition and properties of the main and side products during the implementation of new technologies for producing ethanol
Authors: Zueva N. V. , Agafonov G. V. , Lukinova I. Y. , Dolgov A. N. 
Published: November 2020

The article studied yeast composition isolated from the separation of the mash, bran separated in the grinding step, as well as a protein supplement obtained by mixing these two products. Crude fat content ranges from 4,7 to 6,2%, crude protein content is 38%, which is 20% lower than in the fodder yeast, but 14% higher than that of the bran. It is also found that the resulting protein product enriched in micro- and macro-elements, as well as readily hydrolyzable and water soluble carbohydrates. crude fiber content is 5,5%, which is almost 2,5 times lower than in the bran. The composition of the feed protein supplement obtained with the introduction at the stage of aqueous suspension of wheat powdery cellulolytic enzyme preparation Viskolaza 150 L and without it. The enzyme preparation was added in the step of preparing aqueous suspensions and wheat powdery dosage of 0,01% by weight of the feedstock. protein feed additives obtained with and without addition of cellulolytic enzyme preparation of high quality crude protein content and protein. Thus, the content of crude protein in the protein with the introduction of an additive in an aqueous suspension of powdery Viskolazy 150 L was 37% whereas 34% without the enzyme preparation. The amount of soluble polysaccharides and the mass fraction of ash were practically at the same level of from 2,4 to 5% and from 5,5 to 7,0%, respectively. fiber content of the protein supplement using Viskolazy 150 L was 4,2-6,1%, which is 2,5 times lower than in the protein supplement obtained without enzyme preparation.
The study of the main impurities mature mash depending on the duration of fermentation, yeast alcohol race and used enzyme preparations
Authors: Zueva N. V. , Agafonov G. V. , Novokshenova E. A. , Dolgov A. N. , Chusova A. E. 
Published: November 2020

The paper studied the process of intensification of concentrated fermentation mash with account of the complex amylolytic enzymes, hemicellulase and proteolytic activities. We determined the dependence of ethanol yield, the content of volatile impurities, the content of reducing substances, depending on the different strains of yeast at a seed rate 15 million cells per 1 cm3 wort. To identify the parameters of the fermentation process the wort with an increased solids content, investigated the dynamics of accumulation of volatile impurities by varying the rate and duration of seeding yeast fermentation using 987-O5 race yeast. It revealed that the qualitative composition of impurities in the mash, the resulting wort of high-concentration depends both on the duration of fermentation, and from normal seeding yeast. Thus, depending on the duration of the fermentation process, the acetaldehyde content increases (from 613,17 mg/dm? to 54 h to 1724,6 mg/dm? to 72 hours), the amount of ethyl acetate is reduced (from 409,2 mg/dm? to 54 hours prior to 207 mg/dm? to 72 hours), the methanol content to 54 h at a rate of 15 million yeast seeding cells per 1 cm? of the wort amounted to 0,0043 mg/cm?, whereas by 72 h of fermentation at the same seed rate yeast – 0,0070 mg/dm?, the amount of 1-propanol and 1-butanol was reduced from 903,14 mg/cm? and 6,38 mg/cm? -54 h to 880 mg/cm? and 5,57 mg/cm? - to 72 hours, respectively. The minimum content of isobutanol independent of the duration of fermentation was 900-1100 mg/cm? at a seed rate 15 million yeast cells per 1 cm? wort izoamilola number increases from 1219,08 mg/dm? (54 hr) to 2673,84 mg/dm? (72 h). It revealed that the smallest total amount of impurities obtained by seed rate yeast 15 million cells per 1 cm? wort at the duration of fermentation 54 hours was found that maximum ethanol content in the mash with minimal accumulation therein volatiles corresponds embodiment:. Duration of fermentation - 54 hours at normally the problem of yeast cells – 15,0 million / cm? wort.
Influence of Vitamin D3 Deficiency on the Development of Malocclusions
Authors: Leszczyszyn Anna , Dominiak Marzena , Hnitecka Sylwia 
Published: December 2020

Abstract
Background: Insufficient or excessive growth of the craniofacial bone leads to skeletal and dental defects, which in turn result in the presence of malocclusions. To date, all causes of malocclusion have not been fully explained. In the development of skeletal abnormalities, attention is often paid to general deficiencies - including vitamin D3 deficiency, which causes rickets in growing people. It is suspected that its chronic deficiency may also affect the development of skeletal malocclusion. The aim of the study was to prospectively assess the impact of vitamin D deficiency on the development of malocclusions.Methods: The examination consisted of three parts - (1) medical interview, (2) orthodontic examination along with an alginate impression and radiological imaging, (3) taking a venous blood sample for vitamin D3 level testing.Results: In about 42,1% patients the presence of a skeletal defect was found. In 46,5% of patients presence of dentoalveolar malocclusion occurred. The most common skeletal defect was jaw narrowing in turn, among malocclusions most often retrogenia was diagnosed.Conclusions: A relatively small number of patients in the study group was diagnosed with skeletal malocclusion. Due to effects of vitamin D on the development and metabolism of bones, including jawbones, and the relationship with, for example, rickets, we believe that it would be worthwhile to conduct a study fully focused on the group of patients with skeletal defects.
Mobility-Aware Personalized Service Recommendation in Mobile Edge Computing
Authors: Zhang Hongxia , Dong Yanhui , Yang Yongjin 
Published: December 2020

Abstract
With the proliferation of smartphones and an increasing number of services provisioned by clouds, mobile edge computing (MEC) is emerging as a complementary technology of cloud computing. It could provide cloud resources and services by local mobile edge servers, which are normally nearby users. However, a significant challenge is aroused in MEC because of the mobility of users. User trajectory prediction technologies could be used to cope with this issue, which has already played important roles in service recommendation systems with MEC. Unfortunately, little attention and work have been given in service recommendation systems considering users\' mobility. Thus, in this paper, we propose a mobility-aware personalized service recommendation approach based on user trajectory and QoS predictions. In the proposed method, users' trajectory is firstly discovered by hybrid long-short memory networks. Then, given users\' trajectories, service QoSs are predicted, considering the similarity of different users and different edge servers. Finally, services are recommended by a center trajectory strategy based on the aforementioned information. Experimental results based on the real base station dataset show that our proposed approach can outperform the traditional recommendation approaches in terms of the accuracy in mobile edge computing.
Meta-analysis of the impact of plant invasions on soil microorganism communities
Authors: Torres Nardi , Herrera Ileana , Fajardo Laurie , Bustamante Ramiro 
Published: December 2020

Abstract
One of the ecological impacts generated by invasive plants is the alteration of the microbial community in the soil, which leads to changes in the availability of nutrients and in the assembly of native plant communities. In order to identify which attributes of the soil microbial community was affected by plant invasions, we performed a meta-analysis based on 48 scientific articles that compare these attributes in invaded and non-invaded areas. We analyzed for bacteria, and fungi biomass, richness and diversity; but in some cases lack of studies prevented us for conducting some of the analyses. We use a random effects model to determine the increase or decrease in the values of the response variables, in the presence of invasive plants. The results indicated that the variable responses that change with the invasion of plants is the diversity of bacteria. On the other hand, the diversity of bacteria in the soil increases with the presence of invasive plants, specifically, herbs producing allelopathic substances growing in forest ecosystems of temperate zones. Changes in this variable have consequences on the nutrient cycle, enzymatic activity, mineralization rates and the carbon and nitrogen content of the soil.
Plasma radio–metabolite analysis of PET tracers for dynamic PET imaging: TLC and autoradiography
Authors: Li Fiona , Hicks Justin W , Yu Lihai , Desjardin Lise , Morrison Laura , Hadway Jennifer , Lee Ting-Yim 
Published: November 2020

Abstract
Background In molecular imaging with dynamic PET, the binding and dissociation of a targeted tracer is characterized by kinetics modeling which requires the arterial concentration of the tracer to be measured accurately. Once in the body the radiolabeled parent tracer may be subjected to hydrolysis, demethylation/dealkylation and other biochemical processes, resulting in the production and accumulation of different metabolites in blood which can be labeled with the same PET radionuclide as the parent. Since these radio-metabolites cannot be distinguished by PET scanning from the parent tracer, their contribution to the arterial concentration curve has to be removed for the accurate estimation of kinetic parameters from kinetic analysis of dynamic PET. High performance liquid chromatography has been used to separate and measure radio-metabolites in blood plasma, however, the method is labor intensive and remains a challenge to implement for each individual patient. The purpose of this study is to develop an alternate technique based on thin layer chromatography (TLC) and a sensitive commercial autoradiography system (Beaver, Ai4R, Nantes, France) to measure radio-metabolites in blood plasma of two targeted tracers - [18F]FAZA and [18F]FEPPA , for imaging hypoxia and inflammation respectively. Results Radioactivity as low as 17Bq in 2µL of pig’s plasma can be detected on the TLC plate using autoradiography. Peaks corresponding to the parent tracer and radio-metabolites could be distinguished in the line profile through each sample (n=8) in the autoradiographic image. Significant inter-subject and intra-subject variability in radio-metabolites production could be observed with both tracers. For [18F]FEPPA, 50% of plasma activity was from radio-metabolites as early as 5 min post injection while for [18F]FAZA, significant metabolites did not appear until 50 min post. Simulation study investigating the effect of radio-metabolite in the estimation of kinetic parameters indicated that 32-400% parameter error can result without radio-metabolites correction.Conclusion TLC coupled with autoradiography is a good alternative to high performance liquid chromatography for radio-metabolite correction. The advantages of requiring only small blood samples (~ 100 mL) and of analyzing multiple samples simultaneously, make the method suitable for individual dynamic PET studies.
Self-poisoning with pesticides in Jiangsu Province, China: a cross-sectional study on 24,602 subjects
Authors: Wang Boshen , Han Lei , Wen Jinbo , Zhang Juan , Zhu Baoli 
Published: November 2020

Abstract
Background: With an estimated >800,000 suicide-related deaths and potentially several attempts for each death in the world. The purpose of this study was to determine the epidemiological characteristics of self-poisoning with pesticides within the Jiangsu province in China. Methods: Suicide rate was calculated the Routine Surveillance System by Jiangsu Provincial Center for Disease Control and Prevention, stratified by gender, age and region, combined with socioeconomic and agriculture-related factors to investigate trends in suicide over the study period. A logistic regression model was used to investigate the associations between pesticide types and pesticide-related deaths.Results: In recent years, Jiangsu Province has witnessed a decrease in pesticide self-poisoning cases and consequent deaths. Among all suicides by deliberate ingestion of pesticides, the proportion of cases were mainly in the age 40, accounting for 3.43% of all cases with pesticide suicide. The proportion of suicide due to pesticide poisoning in females was markedly higher than that in males (p<0.001). Suicide using organophosphate and carbamate insecticides was most common, with 10,303 reported cases accounting for 42.02% of all suicides. Conclusions: For national responses to be effective, the characteristics of pesticide suicides should be comprehensively investigated for the formulation of corresponding prevention strategies. At present, more pesticide suicide prevention policies for the elderly people and women should be implemented, and stronger pesticide management policies should be implemented for rural areas.
Association of serum Cyr61 levels with peripheral arterial disease in patients with type 2 diabetes
Authors: Bin Feng , Xu Guidong , Sun Kangyun , Zhang Nannan , Shi Bimin 
Published: November 2020

Abstract
Background: The prevalence of peripheral artery disease (PAD) is obviously increased in diabetic patients. Existing evidences show that cysteine-rich angiogenic inducer 61 (Cyr61), a 40 kD secreted protein, plays important roles in regulating cellular physiological processes. Recent studies have demonstrated a significant correlation between serum Cyr61 levels and atherosclerosis. However, the relationship between Cyr61 levels and PAD in type 2 diabetic patients remains obscure.Methods:. A total of 306 subjects with type 2 diabetes were recruited. The extent of PAD was determined by using the Fontaine classification, which defines four stages. We analyzed Cyr61 serum levels by ELISA in patients with and without PAD at Fontaine’s stage II, III, or IV. Logistic regression models were used to examine the independent association of Cyr61 with PAD.Results: Out of the 306 patients enrolled in this study, 150 patients were free from PAD, while 156 had clinically significant PAD. In PAD patients, the prevalences of Fontaine classification stage II, III and IV were 48.7%, 32.1%, and 19.2%, respectively. Patients with more advanced PAD had significantly higher Cyr61 (P for trend <0.001). The prevalence of PAD on the basis of severity increased with ascending Cyr61 quartiles (all P for trend <0.001), and the severity of PAD was positively correlated with Cyr61 quartiles (r=0.227, P=0.006). The association of Cyr61 levels with PAD remained after adjusting for major risk factors in a logistic regression analysis.Conclusions: Our results demonstrated that Cyr61 was significantly increased in type 2 diabetic patients with PAD and that Cyr61 levels were positively associated with disease severity. It could be a promising biomarker and further studies are needed to assess its clinical utility.
Antimicrobial Resistance in Hospitalized Surgical Patients: a Silently Emerging Public Health Concern in Benin.
Authors: YEHOUENOU Carine Laurence , KPANGON Arsène A. , AFFOLABI Dissou , RODRIGUEZ-VILLALOBOS Hector , Bambeke Françoise Van , DALLEUR Olivia , SIMON Anne 
Published: November 2020

Abstract
Background: Surgical site infections are related to high morbidity, mortality and healthcare costs. As the emergence of multidrug-resistant bacterial pathogens in hospitals is becoming a worldwide challenge for surgeons who treat healthcare-associated infections, we wished to identify the causative agents involved in surgical site infections and their susceptibility pattern in six public hospitals in Benin. Methods: Using standard microbiological procedures, we processed pus specimens collected from obstetrics and gastrointestinal surgery wards. Mass spectrometry (MALDI-TOF) was used for confirmation. The antibiotic susceptibility test firstly used the Kirby-Bauer disc diffusion method. The secondary test by microdilution used the Beckton Dickinson Phoenix automated system (Becton Dickinson Diagnostic, USA). Results: We included 304 patients (mean age 32 ± 11 years), whose median length of stay was 9 days. A total of 259 wound swabs (85.2%) had positive aerobic bacterial growth. In obstetrics S. aureus (28.5%, n=42) was the most common isolate. In contrast, Gram-negative bacteria (GNB) were predominant in gastrointestinal surgery. The most dominant being E.coli (38.4%, n=31). Overall, 90.8% (n=208) of aerobic bacteria were multidrug resistant. Two-third of S. aureus (65.3%, n= 32) were methicillin-resistant Staphylococcus aureus (MRSA), three of which carried both MRSA and induced clindamycin resistance (ICR). GNB showed high resistance to ceftazidime, ceftriaxone and cefepime. Extended-spectrum beta-lactamases were presented by 69.4% of E.coli (n=43/62) and 83.3% of K. pneumoniae (n=25/30). Overall, twelve Gram negative bacteria (5.24%) isolates showed resistance to at least one carbapenem. No isolates showed a wild-type susceptible phenotype.Conclusion: This study shows the alarming prevalence of multidrug resistant organisms from surgical site infections in Benin hospitals. To reduce the spread of these multidrug-resistant bacteria, periodic surveillance of surgical site infections and strict adherence to good hand-hygiene practice are essential.