bluuebunny/crossref_metadata_2025_split huggingface dataset:
Organizational culture now and going forward
Authors: Baek Pyounggu , Chang Jihyun , Kim Taesung 
Published: October 2019

PurposeThe purpose of this paper is to examine the fundamental premises (i.e. perspectives on organizations and intrinsic research contributions) embodied in the literature on organizational culture and offer insights into where organizational culture research should be headed now and going forward.Design/methodology/approachThis research provides an integrative review of organizational culture research and investigates commonalities and differences in terms of the fundamental premises between North America and Europe.FindingsThe findings include that the modern perspective was most pervasive (87 percent) in both regions, with Europe slightly more open to varied perspectives such as symbolic and postmodern ones; approximately 70 percent of the studies were geared toward organization-level contributions, less than 10 percent toward individual-level contributions, and less than 20 percent toward mega-level contributions as the underlying research intent; and (c) in terms of the perspective-contribution combination, the pair of modern perspective and organization-level contribution was most dominant in both regions, while the individual-level contribution was paired with no other perspectives than the modern one.Research limitations/implicationsThis research suggests that the research community shape a whole new discourse on organizational culture and recommends several promising research avenues.Originality/valueBy engaging in fundamental discussions on how an organization has been perceived and what purpose it has meant to deliver, this research offers an overarching view of where we stand currently and possibly where we should be heading in terms of organizational change management.
Accounting for certified emission reductions (CERs) in India
Authors: Kumar Praveen , Firoz Mohammad 
Published: October 2019

Purpose
The purpose of this paper is to analyse the certified emission reduction (CERs) disclosure and reporting practices followed by Indian firms.

Design/methodology/approach
The study is based on all 131 Indian firms who received the CERs under the CDM of UNFCCC. The content analysis is being used to examine the recognition, measurement, presentation and disclosure of CERs within the financial statements.

Findings
The study found that there is generally no uniformity of accounting for CERs. The firms adopted a diversity of accounting practices. More specifically, majority of companies (40.46 per cent) recognised CERs as the other income; a very high non-disclosure rate (91.60 per cent) for valuation of CERs inventories was found as only four companies (3.05 per cent) provided accounting treatment for CERs inventories at lower of cost or net realisable value followed by three companies (2.29 per cent) accounted for these inventories at Net realisable value at the end of the reporting period; similarly, a very high non-disclosure rate (92.36 per cent) for how companies account for expenses incurred in earning these credits was found.

Research limitations/implications
The study will be useful for a wide array of audiences ranging from accounting standard setter to the auditors. The present analysis is based on secondary data, as we examined only annual reports of the sample companies to know how they recognise their earned CERs within the financial statements. So, we did not cover the opinions of various key persons of companies like an accountant, auditors etc. which could be a limitation of this study in validating CERs disclosure practices followed by the Indian firms.

Originality/value
To the best of the author's knowledge, the present study is a first of its kind to analyse the carbon credit disclosure practices in the context of a developing country.
Why are most physicochemical parameters not useful in predicting the quality of sheep milk?
Authors: Tribst Alline Artigiani Lima , Falcade Luiza Toledo Piza , Leite Júnior Bruno Ricardo de Castro , de Oliveira Miguel Meirelles 
Published: October 2019

The impact of microbial growth on the physicochemical parameters of sheep milk was evaluated. The total bacterial counts (TBC) showed a lag phase of 4 h and µ‐max of 0.4 log/h. After 8.4 h, the TBC reached the limit established by European Community, pH had a reduction of 0.04, acidity had an increase in 0.04%, and no changes were observed in the ethanol stability. The milk became thermally unstable after 17 h (109 cfu/mL), when the pH was 5.71, acidity was 0.36%, and ethanol stability was 21.3%. These results highlighted the extreme stability of sheep milk protein and that acidity may be the best physicochemical parameters to predict the quality of sheep milk.
The effect of the endosymbiont Wolbachia on the behavior of insect hosts
Authors: Bi Jie , Wang Yu‐Feng 
Published: October 2019

AbstractAs one of the most successful intracellular symbiotic bacteria, Wolbachia can infect many arthropods and nematodes. Wolbachia infection usually affects the reproduction of their hosts to promote their own proliferation and transmission. Currently, most of the studies focus on the mechanisms of Wolbachia interactions with host reproduction. However, in addition to distribution in the reproductive tissues, Wolbachia also infect various somatic tissues of their hosts, including the brain. This raises the potential that Wolbachia may influence some somatic processes, such as behaviors in their hosts. So far, information about the effects of Wolbachia infection on host behavior is still very limited. The present review presents the current literature on different aspects of the influence of Wolbachia on various behaviors, including sleep, learning and memory, mating, feeding and aggression in their insect hosts. We then highlight ongoing scientific efforts in the field that need addressing to advance this field, which can have significant implications for further developing Wolbachia as environmentally friendly biocontrol agents to control insect‐borne diseases and agricultural pests.
Healthy Eating Index‐2015 as a predictor of ulcerative colitis risk in a case–control cohort
Authors: Rahmani Jamal , Varkaneh Hamed Kord , Ryan Paul M. , Zarezadeh Meysam , Rashvand Samaneh , Clark Cain , Day Andrew S , Hekmatdoost Azita 
Published: October 2019

ObjectiveThere is compelling clinical evidence implicating certain dietary components in the development and clinical course of progression in ulcerative colitis (UC). This study aimed to assess whether any association exists between ulcerative colitis and scores on a healthy eating index.MethodsIn this case‐control study patients with UC were recruited and assessed together with healthy controls. The participants completed a validated 168‐item food frequency questionnaire, the results of which were subsequently used to generate individual healthy eating index (HEI‐2015) scores.ResultsAltogether 58 patients with UC and 123 healthy controls were recruited. After controlling for confounding factors, participants who were in the highest quartile of the HEI‐2015 had a 66% lower odds ratio (OR) of UC than the lowest quartile (OR = 0.34, 95% confidence interval 0.12‐0.96).ConclusionHEI‐2015 was associated with UC in this cohort. Further elucidation of the role of key dietary elements is now warranted.
Nevirapine inhibits migration and invasion in dedifferentiated thyroid cancer cells
Authors: Shang Hongxia , Zhao Junyu , Yao Jinming , Wang Huanjun , Wang Shengnan , Dong Jianjun , Liao Lin 
Published: October 2019

BackgroundMetastatic or recurrent thyroid cancer often behaves aggressively, and approximately two‐thirds of patients present with radioiodine resistance. Effective therapies to suppress thyroid cancer metastasis are urgently needed. Nevirapine has been proved to suppress tumor growth and induce differentiation in several tumor cells, but has not previously been evaluated in metastasis of thyroid cancer. The present study aimed to investigate the effect of nevirapine on migration and invasion in dedifferentiated thyroid cancer cells.MethodsHuman dedifferentiated thyroid cancer cell line (WRO 82‐1) was subject to real‐time quantitative PCR, western blot and transwell migration/invasion assays. The liver metastasis in tumor xenografts of nude mice was subject to hematoxylin‐eosin (HE) staining.ResultsNevirapine significantly repressed cell migration and invasion in WRO 82‐1 cells, and surprisingly significantly decreased liver metastatic tumor in the nude mouse model of dedifferentiated thyroid cancer compared with that of the control. Moreover, nevirapine significantly decreased the expression of IL‐6 mRNA and phosphorylation of JAK2 (Y1007+Y1008) and STAT3 (Tyr 705) in WRO 82‐1 cells compared with those in control cells.ConclusionOur findings suggest that nevirapine significantly repressed migration and invasion/metastasis in WRO 82‐1 cells and tumor xenografts, which may be related to inhibition of IL‐6/STAT3 signaling pathway. It promises great potential as a novel therapy for thyroid cancer, especially for those patients with metastasis.
A comparison of trends in wastewater‐based data and traditional epidemiological indicators of stimulant consumption in three locations
Authors: Goulding Neil , Hickman Matthew , Reid Malcolm , Amundsen Ellen J. , Baz‐Lomba Jose Antonio , O'Brien Jake W. , Tscharke Ben J. , de Voogt Pim , Emke Erik , Kuijpers Wil , Hall Wayne , Jones Hayley E. 
Published: October 2019

AbstractAimsTo compare long‐term trends in wastewater data with other indicators of stimulant use in three locations and to test the reliability of estimates based on 1 week of sampling.DesignComparison of trends in quantities (‘loads’) of stimulants or their metabolites in wastewater with trends in other indicators of stimulant use (e.g. treatment, police, population survey data).Setting and ParticipantsPopulations in Oslo (Norway), South‐East Queensland (Australia) and Eindhoven (the Netherlands).MeasurementsWastewater data were modelled for MDMA (3,4‐methyl​enedioxy​methamphetamine), benzoylecgonine (a metabolite of cocaine), amphetamine and methamphetamine in Oslo; benzoylecgonine in Eindhoven; and methamphetamine in South‐East Queensland. Choice of stimulants modelled in each region was primarily determined by availability of useable data.FindingsIn Oslo, wastewater data, driving under the influence of drugs statistics and seizure data all suggested increasing MDMA use between 2009 and 2017. In South‐East Queensland, there was an estimated 31.1% [95% confidence interval (CI) = 29.4–32.9%] annual increase in daily loads of methamphetamine in wastewater between 2009 and 2016, compared with a 14.1% (95% CI = 10.9–17.3%) annual increase in seizures. Some of the increase in wastewater can be explained by increased purity. In Eindhoven, there was no evidence of a change in cocaine consumption from wastewater, but a reduction was observed in numbers in treatment for cocaine use from 2012 to 2017. In approximately half the cases examined in Oslo, credible intervals around estimates of annual average loads from a regression model versus estimates based on a single week of sampling did not overlap.ConclusionsLong‐term trends in loads of stimulants in wastewater appear to be broadly consistent with trends in other indicators of stimulant use in three locations. Wastewater data should be interpreted alongside epidemiological indicators and purity data. One week of wastewater sampling may not be sufficient for valid inference about drug consumption.
The effect of cricoid and paralaryngeal force on upper oesophageal occlusion during induction of anaesthesia: a randomised, crossover study
Authors: Kim H. , Chang J.‐E. , Won D. , Lee J.‐M. , Jung J.‐Y. , Choi S. , Min S.‐W. , Hwang J.‐Y. 
Published: October 2019

SummaryThe aim of this study was to evaluate the effectiveness of cricoid and paralaryngeal force for oesophageal entrance occlusion during induction of anaesthesia. Seventy‐four patients were included in this randomised, crossover study. The relative position of the glottis and outer anteroposterior diameter of the upper oesophageal entrance were assessed at baseline, after the application of 30 N cricoid and paralaryngeal force, and after induction of anaesthesia. The occlusion rate of the oesophageal entrance with cricoid and paralaryngeal force was assessed during direct laryngoscopy. The relative position of the upper oesophageal entrance to the glottis changed in 45 out of 74 patients after induction of anaesthesia and during direct laryngoscopy compared with the awake state. The application of cricoid and paralaryngeal force decreased the mean (SD) diameter of the upper oesophageal entrance to a similar degree in awake (8.5 (2.1) mm to 6.4 (1.7) mm and 6.5 (1.6) mm, respectively; p < 0.001) and anaesthetised (8.7 (2.2) mm to 6.5 (1.7) mm and (6.7 (1.9) mm, respectively; p < 0.001) states. During direct laryngoscopy, the occlusion rate of the oesophageal entrance was greater with cricoid compared with paralaryngeal force (46/74 vs. 26/74, respectively; p = 0.002). The relative position of the upper oesophageal entrance to the glottis may change after induction of anaesthesia and during direct laryngoscopy. Cricoid and paralaryngeal force both decrease the diameter of the upper oesophageal entrance in awake and anaesthetised states. Occlusion of the oesophageal entrance is achieved more frequently with cricoid force compared with paralaryngeal force during direct laryngoscopy.
Multi‐site evaluation of partnered pharmacist medication charting and in‐hospital length of stay
Authors: Tong Erica Y. , Mitra Biswadev , Yip Gary , Galbraith Kirstie , Dooley Michael J. ,   PPMC Research Group
Published: October 2019

AimsTo undertake a multicentre evaluation of translation of a partnered pharmacist medication charting (PPMC) model in patients admitted to general medical units in public hospitals in the state of Victoria, Australia.MethodsUnblinded, prospective cohort study comparing patients before and after the intervention. Conducted in seven public hospitals in Victoria, Australia from 20 June 2016 to 30 June 2017. Patients admitted to general medical units were included in the study. Medication charting by pharmacists using a partnered pharmacist model was compared to traditional medication charting. The primary outcome variable was the length of inpatient hospital stay. Secondary outcome measures were medication errors detected within 24 h of the patients' admission, identified by an independent pharmacist assessor.ResultsA total of 8648 patients were included in the study. Patients who had PPMC had reduced median length of inpatient hospital stay from 4.7 (interquartile range 2.8–8.2) days to 4.2 (interquartile range 2.3–7.5) days (P < 0.001). PPMC was associated with a reduction in the proportion of patients with at least 1 medication error from 66% to 3.6% with a number needed to treat to prevent 1 error of 1.6 (95% confidence interval: 1.57–1.64).ConclusionExpansion of the partnered pharmacist charting model across multiple organisations was effective and feasible and is recommended for adoption by health services.
Insomnia symptoms and asthma control—Interrelations and importance of comorbidities
Authors: Sundbom Fredrik , Malinovschi Andrei , Lindberg Eva , Almqvist Catarina , Janson Christer 
Published: October 2019

AbstractBackgroundInsomnia symptoms are common with asthma. The aim of the study was to analyse the associations between insomnia symptoms and asthma control, asthma severity, and asthma‐related comorbidity in a community‐based population.MethodsAdults (n = 23 875, ages 18‐45) from the community‐based LifeGene study answered a questionnaire on insomnia symptoms, airway symptoms, asthma diagnosis, asthma medication, and asthma‐related comorbidities (chronic rhinosinusitis, gastro‐oesophageal reflux, anxiety, depression, or obesity).ResultsOf the participants, 1272 (5.3%) had asthma. The prevalence of any insomnia symptom was higher in participants with uncontrolled asthma (n = 201) than with controlled or partially controlled asthma (32.2% vs 19.9% and 20.1%, respectively, P < .01). There was no significant difference in the prevalence of insomnia symptoms between subjects with controlled asthma and subjects without asthma. Subjects with asthma and any asthma‐related comorbidity reported more insomnia symptoms (29.0% vs 22.4%, P < .01) compared to asthmatics without comorbidity. Moreover, the prevalence was highest among subjects reporting both uncontrolled asthma and any asthma‐related comorbidity (45.1%, P < .01). Uncontrolled asthma remained significantly associated with insomnia symptoms (OR 1.72 (1.15‐2.56)) after adjusting for age, sex, BMI, smoking history, comorbidities, physical activity, and educational level, while medication level was not. Among asthma‐related comorbidities, chronic rhinosinusitis (OR 1.62 (1.20‐2.19)), obesity (1.87 (1.07‐3.25)), and depression (OR 1.85 (1.34‐2.55)) were independently associated with insomnia symptoms.ConclusionUncontrolled asthma was significantly associated with insomnia symptoms, while controlled or partially controlled asthma was not. Asthma‐related comorbidity is of great importance, and asthma control seems to be more important than asthma severity for insomnia symptoms.
Nicotine modulates molecules of the innate immune response in epithelial cells and macrophages during infection withM. tuberculosis
Authors: Valdez-Miramontes C E , Trejo Martínez L A , Torres-Juárez F , Rodríguez Carlos A , Marin-Luévano S P , de Haro-Acosta J P , Enciso-Moreno J A , Rivas-Santiago B 
Published: October 2019

SummarySmoking increases susceptibility to becoming infected with and developing tuberculosis. Among the components of cigarette smoke, nicotine has been identified as the main immunomodulatory molecule; however, its effect on the innate immune system is unknown. In the present study, the effect of nicotine on molecules of the innate immune system was evaluated. Lung epithelial cells and macrophages were infected with Mycobacterium tuberculosis (Mtb) and/or treated with nicotine. The results show that nicotine alone decreases the expression of the Toll-like receptors (TLR)-2, TLR-4 and NOD-2 in all three cell types, as well as the production of the SP-D surfactant protein in type II pneumocytes. Moreover, it was observed that nicotine decreases the production of interleukin (IL)-6 and C-C chemokine ligand (CCL)5 during Mtb infection in epithelial cells (EpCs), whereas in macrophages derived from human monocytes (MDMs) there is a decrease in IL-8, IL-6, tumor necrosis factor (TNF)-α, IL-10, CCL2, C-X-C chemokine ligand (CXCL)9 and CXCL10 only during infection with Mtb. Although modulation of the expression of cytokines and chemokines appears to be partially mediated by the nicotinic acetylcholine receptor α7, blocking this receptor found no effect on the expression of receptors and SP-D. In summary, it was found that nicotine modulates the expression of innate immunity molecules necessary for the defense against tuberculosis.
Predictive multi‐scale occupancy models at range‐wide extents: Effects of habitat and human disturbance on distributions of wetland birds
Authors: Stevens Bryan S. , Conway Courtney J. 
Published: October 2019

AbstractAimPredicting distributions is fundamental to ecology, yet hindered by spatially restricted sampling, scale‐dependent relationships and detection error associated with field surveys. Predictive species distribution models (SDMs) are nonetheless vital for conservation of many species. We developed a framework for building predictive SDMs with multi‐scale data and used it to develop range‐wide breeding‐season SDMs for 14 marsh bird species of concern.LocationUSA.MethodsWe built SDMs using data from range‐wide surveys conducted over 14 years, and habitat and disturbance covariates measured at multiple spatial scales. We built hierarchical occupancy models that included heterogeneity in detectability during sampling, and used Bayesian model selection to regulate model complexity (covariates and scales) based explicitly on spatial predictive abilities. We thus integrated model selection for optimizing out‐of‐sample prediction, range‐wide sampling over broad conditions, multi‐scale analyses and scale optimization, and species‐specific detectability for a suite of wide‐ranging species.ResultsDistributions of marsh birds were affected by local wetland conditions, but also by agricultural, urban and hydrologic disturbances operating from local scales (100–500 m) to the watershed level. Variables measuring human disturbances improved prediction for most species, and every species was affected by attributes at >1 scale. Five species showed evidence for continental‐scale range contraction during the study.Main conclusionsWe demonstrate how hierarchical occupancy models can be optimized for prediction across a species' range at the extent of a continent while also accounting for imperfect detection, and thus describe a generalizable approach that can be used for any species. We provide the first data‐driven, empirical SDMs built at the range‐wide extent for most of our 14 study species and demonstrate that previous studies focused on local distributions and the effects of fine‐scale wetland vegetation missed important broadscale drivers of occupancy for marsh birds.
Echocardiographic reference ranges for myocardial work in healthy subjects: A preliminary study
Authors: Galli Elena , John‐Matthwes Beatrice , Rousseau Chloé , Schnell Frederic , Leclercq Christophe , Donal Erwan 
Published: October 2019

AbstractBackgroundMyocardial work (MW) estimation by pressure‐strain loops (PSL) allows the non‐invasive assessment of myocardial performance. Aim of this study is to provide the reference values for global myocardial work index (WI), constructive work (CW), wasted work (WW), and work efficiency (WE) in a group of healthy volunteers accounting for age and gender.Methods and results2D standard and speckle‐tracking echocardiography were performed in 115 healthy volunteers (median age 36.3 [18–69] years, males: 67%). PSLs were used to assess MW. Mean ± standard deviation or median and inter‐quartile range, 5° and 95° percentile values for global myocardial WI, CW, WW, and WE in the whole population were 1926 ± 247 mm Hg, (1534–2356); 2224 ± 229 mm Hg, (1894–2647); 90 (61–123) mm Hg%, (38–195); and 96 (94–97)%, (91–98), respectively. Global WI (2031 ± 247 vs 1874 ± 232 mm Hg%, P = .001) and global CW (2289 ± 261 vs 2194 ± 207 mm Hg%, P = .04) were higher in women than in men. Age did not affect MW parameters. The segmental analysis showed that myocardial WI, CW, and WE were lower in the left ventricular basal segments than in the apex. The apex‐to‐base gradient was inverted for WW (all P < .0001).ConclusionsThe assessment of MW is feasible in normal subjects. The presented referral ranges of global myocardial WI, CW, WW, and WE were not affected by age. An apex‐to‐base gradient was observed for all MW parameters. Nevertheless, the wide variability of MW parameters prevents for the moment the application of this technique in the routine clinical setting.