bluuebunny/crossref_metadata_2025_split huggingface dataset:
Securing therapeutic justice through mediation: the challenge of medical treatment disputes
Authors: Lindsey Jaime , Doyle Margaret , Wazynska-Finck Katarzyna 
Published: December 2024

Abstract
This paper explores the use of mediation in medical treatment disputes through the lens of therapeutic justice (TJ), a concept developed in the 1990s to consider the therapeutic and anti-therapeutic effects of justice systems. The paper argues that mediation may be a mechanism for achieving therapeutic effects for people involved in medical treatment disputes. In doing so, the paper highlights the conflict that can often arise between healthcare professionals, family members and patients in medical treatment disputes and the related difficulties with using litigation to resolve this type of conflict. It has been suggested by judges, academics and policy-makers that mediation might be a better way of resolving conflict in these cases. While mediation and TJ have much in common, the paper explores the many tensions between them, considering ways in which mediation might need to be done differently to achieve therapeutic aims. Finally, the paper identifies six TJ features against which mediation can be tested to consider whether it can live up to the claims that it can be used to resolve medical treatment disputes more therapeutically.
Plastic waste management strategies toward zero waste: Status, perspectives and recommendations for Ethiopia
Authors: Aragaw Tadele Assefa 
Published: December 2024

Abstract
Since 1979, plastic companies have significantly expanded their markets. Evidence suggests that excessive plastic use in Ethiopia has exacerbated environmental pollution, contributing to a “quadruple crisis” involving climate change, biodiversity loss, pollution and public health and economic impacts. To address this, the Ethiopian government needs to establish effective plastic waste management strategies. Key future direction and recommendation include (1) Developing and enforcing national strategies, including a ban on many single-use plastics, for sustainable plastic waste management; (2) adopting international best practices and policies to move toward a zero-waste approach; (3) investing in a circular economy and plastic waste management systems; (4) strengthening policies through comprehensive legislation and extended producer responsibility frameworks; (5) establishing a council to integrate scientific research into policymaking; (6) promoting green technologies and innovations, such as plastic waste-to-energy and smart waste management; (7) engaging in global efforts to monitor hazardous chemicals in plastics and support transparency in a toxic-free circular economy to ensure the public’s right to information.
Branding the white nation: Platform capitalism and the semiotics of far-right organizing
Authors: Tebaldi Catherine , Del Percio Alfonso 
Published: December 2024

Abstract
This article focuses on the branding of Patriotic Alternative (PA), a British fascist organization and business, in three analytic steps: (i) branding as circulating ideologies as commodities; (ii) branding as creating—and selling—community, and (iii) branding as regimenting meaning. Building on work on the communicability of evil and language, nationalism, and political economy, we explore how PA uses the affordances of platform capitalism in a project that goes beyond ideological normalization: not just rebranding a message as acceptable but selling a product which builds a community aligned with this ideology. Looking at both brand and political websites, YouTube, as well as Telegram channels, we show how PA's branding functions to invest a wide range of mundane practices with racist meaning; they are imagined to forestall the great replacement. Rebranding racism as white community, every cup of tea sold brings back the world of your grandma, each bar of soap protects white skin. (Far-right semiosis, branding, platform capitalism)*
Evaluation of the Maximum Evaporation and the Priestley‐Taylor Models for Inland Waterbodies
Authors: Xiao Wei , Wang Jun , Zhao Ruonan , Jia Lei , Chu Haoran , Bao Hengxin , Cao Chang , Ge Pei , Yang Jian , Zhang Mi , Zhang Zhen , Lee Xuhui 
Published: December 2024

AbstractThe Priestley‐Taylor (PT) model is a classic model of potential evaporation of terrestrial and marine surfaces. It is now recognized that the Bowen ratio (β) implicit in the PT model is too sensitive to temperature. The model also requires the surface net radiation (Rn) as input even though Rn is not an independent external forcing. The maximum evaporation model (MEM) proposed by Yang and Roderick (2019, https://doi.org/10.1002/qj.3481) is a potential candidate for replacing the PT model. Past studies have evaluated the MEM for land ecosystems and for the global ocean. This study represents the first evaluation of the MEM for inland waterbodies. Results are based on eddy‐covariance observation at a large lake and at a small fishpond. Although there were complex error structures and error compensation patterns among its intermediate variables, the MEM was able to reproduce the observed monthly (R2 > 0.95) and interannual variability (R2 > 0.78) in the lake latent heat flux. A key assumption of the MEM, that the incoming and outgoing longwave radiation is coupled, was a reasonable approximation at both the monthly and the annual time scale for the large lake and at the monthly time scale for the small fishpond. This assumption allows the MEM to treat Rn as an intermediate variable instead of a prescribed forcing. These results support the MEM as an alternative to the PT model at locations where Rn measurements are not available. In situations where Rn data is available, a revised PT model with reduced β temperature sensitivity is recommended.
Western Pacific Warm Pool Warming and Salinity Front Expansion Since 1821 Reconstructed From Paired Coral δ18O, Sr/Ca, and Reconstructed δ18Osw
Authors: Todorović Sara , Wu Henry C. , Linsley Braddock K. , Kuhnert Henning , Menkes Christophe , Isbjakowa Albina , Dissard Delphine 
Published: December 2024

AbstractThe Southwest Pacific region is of great importance to global climate variability, but instrumental climate observations before the 1980s lack in numbers and quality. Despite efforts in complementing instrumental records with proxy sea surface temperature (SST) and sea surface salinity (SSS) reconstructions based on coral Sr/Ca and δ18Osw records, few of them are longer than a century. This study introduces a northwestern extension to the existing records of South Pacific coral study sites with monthly‐resolved Sr/Ca, δ18O, and δ18Osw reconstructions from Rotuma dating back to 1821. Additionally, we present new monthly‐resolved Sr/Ca and reconstructed δ18Osw from a coral from Tonga dating back to 1848. Results reveal 1.5°C warming in the Western Pacific Warm Pool, while the adjacent coral from Tonga shows 1°C warming over the twentieth century. The Rotuma Sr/Ca record reveals thermal stress events impacting the Sr/Ca‐SST relationship in the following months. Coral δ18Osw results reveal significant freshening of 0.45 Sp (practical salinity unit) in Tonga since the early twentieth century, suggesting the southeastward expansion of the South Pacific Convergence Zone salinity front. The δ18Osw inferred SSS provides a valuable extension into the past considering the short and inconsistent instrumental records available. This study demonstrates the utility of coral‐based reconstructions in capturing long‐term and regional climate variations in the Southwest Pacific and the necessity of expanding replicated studies to other underrepresented areas to enhance our understanding of regional climate dynamics.
Turbulence and Bedload Transport in Submerged Vegetation Canopies
Authors: Zhao Tian , Nepf Heidi 
Published: December 2024

AbstractUsing a constant channel velocity, , flume experiments investigated how canopy density (, with canopy frontal area per unit volume , and canopy height ) and submergence ratio (, with the flow depth) impacted near‐bed velocity, turbulence, and bedload transport within a submerged canopy of rigid model vegetation. For < 2, the near‐bed turbulent kinetic energy (TKE) was predominantly stem‐generated. As increased, both the near‐bed TKE and bedload transport rate () increased. For > 2, the near‐bed TKE was insensitive to and , because of a trade‐off between decreasing stem‐generated turbulence and increasing canopy‐shear‐generated turbulence, as and increased. However, the near‐bed velocity declined with increasing and , such that, even with a constant TKE, also declined. These trends highlight that both TKE and velocity were important in controlling bedload transport. Models to predict velocity, TKE, and bedload transport were developed and validated with measurements. The models were then used to explore conditions more relevant to the field, specifically with constant energy slope () and flexible vegetation. For a constant energy slope, increased as decreased and as increased, which in turn influenced the in‐canopy velocity and TKE. The highest occurred with the greatest and smallest , corresponding to the highest and greatest contribution of canopy‐shear‐generated turbulence, reflecting the importance of canopy‐shear‐generated turbulence in submerged canopies. The lowest occurred with smallest and highest , corresponding to the smallest and least contribution of canopy‐shear‐generated turbulence.
Epigenetic reprogramming in mouse and human primordial germ cells
Authors: Lee Sun-Min , Surani M. Azim 
Published: December 2024

AbstractPrimordial germ cells (PGCs) are the precursors of sperm and eggs. They undergo genome-wide epigenetic reprogramming to erase epigenetic memory and reset the genomic potential for totipotency. Global DNA methylation erasure is a crucial part of epigenetic resetting when DNA methylation levels decrease across the genome to <5%. However, certain localized regions exhibit slower demethylation or resistance to reprogramming. Since DNA methylation plays a crucial role in transcriptional regulation, this depletion in PGCs requires mechanisms independent of DNA methylation to regulate transcriptional control during PGC reprogramming. Histone modifications are predicted to compensate for the loss of DNA methylation in gene regulation. Different histone modifications exhibit distinct patterns in PGCs undergoing epigenetic programming at the genomic level during PGC development in conjunction with changes in DNA methylation. Together, they contribute to PGC-specific genomic regulation. Recent findings related to these processes provide a comprehensive overview of germline epigenetic reprogramming and its importance in mouse and human PGC development. Additionally, we evaluated the extent to which in vitro culture techniques have replicated the development processes of human PGCs.
Achieving the optimal emergence profile: the role of soft tissue grafting and pontic site development
Authors: Brennand Roper ﻿Matthew , Fields Yasmin 
Published: December 2024

AbstractHard and soft tissue remodelling after tooth extraction may result in a concave profile at the subsequent edentulous ridge. This defect may result in a sub-optimal aesthetic transition zone between the soft tissue and the pontic, which may appear to sit on the ridge, rather than emanating from within the ridge, as would a natural tooth. To optimise aesthetics, pontic site augmentation (PSA) (increasing the volume at the pontic site) and pontic site development (PSD) (remodelling the tissue at the pontic site) may provide a solution.This article discusses the role of soft tissue grafting for PSA, alongside the techniques employed for PSD. Biomaterial substitutes may be used for soft tissue grafting; although autogenous tissue remains the gold standard. Patients may benefit from biomaterial substitutes (as no donor site is required) but evidence for long-term volumetric stability within this specific scenario is limited.Studies suggest PSD may be initiated three months post-augmentation, with minimal changes in site volume following this time point; although again, clinical data are limited. PSD can be achieved via several techniques, depending on operator and patient preference, with the ultimate goal of tissue conditioning to accept a convex fit surface that facilitates hygiene practices. PSA and PSD play key roles in the creation of a natural emergence profile at edentulous sites, leading to optimal aesthetics and cleansability.
Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases
Authors: Cheetham Max J. , Huo Yunlong , Stroyakovski Maria , Cheng Li , Wan Daniel , Dell Anne , Santini Joanne M. 
Published: December 2024

Abstract
Klebsiella pneumoniae is an opportunistic pathogen with significant clinical relevance. K. pneumoniae-targeting bacteriophages encode specific polysaccharide depolymerases with the ability to selectively degrade the highly varied protective capsules, allowing for access to the bacterial cell wall. Bacteriophage depolymerases have been proposed as novel antimicrobials to combat the rise of multidrug-resistant K. pneumoniae strains. These enzymes display extraordinary diversity, and are key determinants of phage host range, however with limited data available our current knowledge of their mechanisms and ability to predict their efficacy is limited. Insight into the resolved structures of Klebsiella-specific capsule depolymerases reveals varied catalytic mechanisms, with the intra-chain cleavage mechanism providing opportunities for recombinant protein engineering. A detailed comparison of the 58 characterised depolymerases hints at structural and mechanistic patterns, such as the conservation of key domains for substrate recognition and phage tethering, as well as diversity within groups of depolymerases that target the same substrate. Another way to understand depolymerase specificity is by analyzing the targeted capsule structures, as these may share similarities recognizable by bacteriophage depolymerases, leading to broader substrate specificities. Although we have only begun to explore the complexity of Klebsiella capsule depolymerases, further research is essential to thoroughly characterise these enzymes. This will be crucial for understanding their mechanisms, predicting their efficacy, and engineering optimized enzymes for therapeutic applications.
Relationships Between Hearing-Related and Health-Related Variables in Academic Progress of Children With Unilateral Hearing Loss
Authors: Picou Erin M. , Davis Hilary , Tang Leigh Anne , Bastarache Lisa , Tharpe Anne Marie 
Published: December 2024

Purpose:
School-age children with unilateral hearing loss are at an increased risk of exhibiting academic difficulties. Yet, approximately half of children with unilateral hearing loss will not require additional support. There is a dearth of information to assist in determining which of these children will express academic deficits and which will not. The purpose of this study was to identify hearing- and health-related factors that contribute to adverse educational progress in children with permanent unilateral hearing loss. Specific indicators of academic concern identified during school age included the need for specialized academic services, receipt of speech-language therapy, or parent/teacher concerns for academics or speech-language development.

Method:
This study provides an in-depth analysis of a previously described patient cohort developed from de-identified electronic health records. Factors of interest included potentially relevant hearing-related risk factors (e.g., degree, type, and laterality of hearing loss), in addition to health-related factors that could be extracted from the electronic health records (e.g., sex, premature birth, history of significant otitis media).

Results:
Being born preterm, having a history of pressure equalization tubes or having conductive or mixed hearing loss more than doubled the risk of demonstrating adverse educational progress. Laterality and degree of loss were generally not significantly related to academic progress.

Conclusions:
Approximately half of school-age children with permanent unilateral hearing loss in this cohort experienced some academic challenges. Birth history and middle ear pathology were important predictors of adverse educational progress.
Le monoxyde d’azote : un nouvel éclairage sur la nécessité du rétablissement d’une ventilation nasale
Authors: Amat Philippe , Charavet Carole 
Published: December 2024

Le monoxyde d’azote (NO) est libéré par les cellules endothéliales, les cellules du foie, les neurones et les macrophages. Dans l’organisme, le monoxyde d’azote remplit plusieurs fonctions clés. Par exemple, il prévient et traite l’hypertension, maintient la souplesse des artères et réduit le risque de formation de caillots dans le sang. Ainsi, il limite significativement les risques de maladies cardio-vasculaires et d’accidents vasculaires cérébraux. De plus, il aide à combattre les agents pathogènes, il favorise la cicatrisation de la peau et il intervient dans les mécanismes de la mémorisation.
En outre, le monoxyde d’azote nasal tient une place importante dans la physiologie respiratoire. Présent dans l’air expiré chez l’homme, il provient principalement des voies respiratoires supérieures chez les individus sains et au repos, avec une contribution mineure des voies respiratoires inférieures et des poumons. Il est synthétisé au niveau des sinus paranasaux lors de l’inhalation par le nez, mais il n’est pas produit lors de l’inhalation par la bouche.
La ventilation nasale et la mobilisation associée du NO des sinus par auto-inhalation induisent des effets significatifs à la fois localement et à distance, notamment en participant à la défense immunitaire de l’hôte et à la régulation de la fonction pulmonaire.
Cette découverte apporte un nouvel éclairage sur la nécessité de rétablir une ventilation nasale optimale, démarche qui est soutenue, entre autres, par les traitements d’orthopédie dento-faciale associés à une rééducation myofonctionnelle oro-faciale (RMOF) et l’utilisation d’une gouttière de rééducation préfabriquée (GRP).
Physiotherapiewissenschaft umfassend verstehen: Ein angewandter Überblick über verschiedene Forschungsparadigmen (Teil 1)
Authors: Bopp Katharina , Haase Laura A. , Maric Filip 
Published: December 2024

Die internationale Gesundheits- und Physiotherapieforschung hat sich in den letzten Jahrzehnten durch den Gebrauch und die Weiterentwicklung verschiedenster wissenschaftstheoretischer Grundlagen vielfältig entwickelt. Dadurch wird aktuellen Fragen und Problemstellungen auf unterschiedliche Weise begegnet und aktiv zur Veränderung beigetragen. Im deutschsprachigen Raum ist diese Vielfalt der wissenschaftstheoretischen Arbeit noch nicht im selben Grade zu verzeichnen. Die übliche Unterscheidung in quantitative und qualitative Forschung trägt zu Missverständnissen bei, wodurch die in diesen Begriffen implizierte Vielfalt sowohl für die Theorieentwicklung als auch für die angewandte Forschung verloren geht.In einem zweiteiligen Artikel wird ein Überblick über die in der internationalen Gesundheits- und Physiotherapieforschung gängigsten Forschungsparadigmen gegeben, um deren grundlegendes Verständnis und zukünftige Anwendung in der deutschsprachigen Physiotherapiewissenschaft zu fördern.Im ersten Teil werden wichtige begriffliche Grundlagen geklärt, anschließend folgt eine Auseinandersetzung mit dem Positivismus und Interpretativismus sowie eine Zusammenfassung. Im zweiten Teil werden das kritische Paradigma und der Poststrukturalismus erläutert, anschließend werden die Bedeutung der verschiedenen Forschungsparadigmen für den wissenschaftlichen Diskurs in der Physiotherapie diskutiert.Bei der näheren Behandlung jedes Paradigmas werden die ihnen zugrundeliegenden ontologischen, epistemologischen und methodologischen Grundannahmen besprochen sowie die sich aus diesen ergebenden praktischen Möglichkeiten. Diese Möglichkeiten werden dann anhand plakativer Forschungsfragen zum Thema der Akademisierung veranschaulicht. Damit wird auch die Notwendigkeit paradigmatischer Vielfalt in der Physiotherapieforschung verdeutlicht, die benötigt wird, um den komplexen Problemen der aktuellen Zeit gerecht zu werden.Die vorliegende Darstellung klärt ebenfalls, dass expliziter und stringenter Theoriebezug in der Physiotherapiewissenschaft unabdingbar ist. Für diesen Theoriebezug bedarf es in der Zukunft weitere Auseinandersetzung mit den hier vorgestellten Paradigmen, deren Details, Nuancen, Unter- und Mischvarianten, die über den ersten Überblick hinausgehen. Wenn wir auf diese Weise Wissenschaft umfassender verstehen, kann diese in noch größerem Ausmaß als bisher sowohl zur Weiterentwicklung der Physiotherapie als auch zur Gesundheit beitragen.
Intra–Abdominal Desmoplastic Small Round Cell Tumor: A Rare Case Report and Review of Literature
Authors: Mudgal Ankur , Sharma Devender , Singhal Vikram , Vaid Ashok 
Published: December 2024

AbstractDesmoplastic small round cell tumor (DSRCT) is a rare and aggressive type of sarcomatous tumor with a high proclivity ofmetastasis.While it predominantly affects the abdominal cavity, it is most often observed in younger males and histopathologically identified by vascular and collagenous stroma containing groups of small tumor cells. However, standardized treatment approaches are currently unavailable. Here, we present the case of a 47-year-old man diagnosed with intra-abdominal metastatic DSRCT managed with multiple lines of chemotherapy followed by surgical debulking. Overall survival of 32 months is achieved with good quality of life.
Modified Keystone a Versatile Flap Reconstruction for Mastectomy Defects: Our Clinical Experience
Authors: Harsono Anastasia Dessy , Tjokrovonco Dominic Melino , Bas Birgita Maria Ratu Rosari , Putra Pratama Mandala 
Published: December 2024

Abstract
Introduction The closure of extensive defects in reconstructive surgery is a common challenge. The keystone flap technique has gained popularity due to its adaptability and reliance on fascia, providing a reliable blood supply and offering a better match for skin color compared with skin grafts. However, keystone flap necrosis can occur due to tension and inadequate tissue perfusion. To address this, a modified keystone flap technique called the “doubled-handle saucepan” was developed, resulting in improved flap vitality and reduced tissue necrosis, particularly in mastectomy defects.
Materials and Method We assessed 16 female patients who underwent “doubled-handle saucepan” keystone flaps after modified radical mastectomy (MRM). The average dimensions of wounds in this study were 23.1 ± 3.8 cm × 16.9 ± 2.9 cm, with the largest defect measuring 28.0 cm × 21.5 cm. The average size of the modified keystone flap was 36.3 ± 3.8 cm × 21.2 ± 2.2 cm.
Results Modified keystone flap demonstrated effective performance in managing extensive defects without any complication. The average operation time in our study was 124.3 ± 11.2 minutes.
Conclusion The “double-handled saucepan” keystone flap technique is a unique and dependable method derived from the original keystone flap, which effectively covers defects and maintains flap vitality without tension by ensuring vascularization at the skin bridge. This modified keystone flap technique proves highly effective for reconstruction after MRM, offering time efficiency and no need for a secondary donor site, making it an appealing alternative to free flaps or other local flap techniques in many cases.