bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cannabis use and co-use in tobacco smokers and nonsmokers: prevalence and associations with mental health in a cross-sectional, nationally representative sample ofadults in Great Britain, 2020
Authors: Hindocha Chandni , Brose Leonie , Walsh Hannah , Cheeseman Hazel 
Published: December 2020

This study has published https://onlinelibrary.wiley.com/doi/abs/10.1111/add.15381

BACKGROUND AND AIMS: In Great Britain, cannabis and tobacco are commonly used substances, both independently and together. Use of either substance is associated with mental health problems, but prevalence of co-use within these populations is unknown. We aimed to 1) estimate prevalence of cannabis use, frequency of use and routes of administration (ROA) among tobacco smokers and non-smokers and 2) investigate mental health problems amongst non-users, tobacco-only, cannabis-only and co-users of both substances.

DESIGN: Cross-sectional national online survey (Action on Smoking and Health) fielded in February–March 2020.

SETTING: Great Britain

PARTICIPANTS: Adults in Great Britain aged ≥ 18 year (n = 12,809)

MEASUREMENTS: Tobacco use status (smoker [daily or non-daily] or non-smoker [never or ex-smoker]), cannabis use frequency (never to daily), detailed ROAs of cannabis, self-reported treatment for mental health disorders (depression, anxiety, and any). Statistically weighted prevalence estimates were computed to ensure representativeness. Correlates were assessed using chi-squared tests and logistic regression.

FINDINGS: In Great Britain in 2020, 7.1% of the sample had used cannabis in the past year. Tobacco smokers had greater odds of using cannabis in the past year (21.9%) and using cannabis daily (8.7%) than non-smokers (past-year: 4.7%; aOR=10.07, [95% CI: 8.4 -12.0]; daily: 0.7%; aOR=24.6, [95% CI: 17.96-35.55]). Co-administration with tobacco was common (46.2% of non-smokers, 80.8% of tobacco smokers). Co-users reported the highest prevalence of any treatment for mental health problems (54.2%) in comparison to cannabis-only (45.8%), tobacco-only (33.2%) and non-users (22.7%; all p≤0.05).

CONCLUSION:

Approximately one in 13 adults in Great Britain reports having used cannabis in the past year, approximately four times as many among cigarette smokers as non-smokers. Co-administration of cannabis and tobacco, via smoking, appears to be common, including among self-identified non-smokers. Mental health problems appear to be particularly common among dual users.
Net Irrigation Requirements for Florida Turfgrass Lawns: Part 3 - Theoretical Irrigation Requirements
Authors: Romero Consuelo C. , Dukes Michael D. 
Published: December 2020

Urban water users need specific recommendations to irrigate efficiently and for planning and regulatory programs. This 21-page fact sheet estimates net irrigation, effective rainfall, and drainage by using a water balance equation for ten locations in Florida and one in Alabama from data during the 30-year period of 1980-2009. Written by Consuelo C. Romero and Michael D. Dukes and published by the UF Department of Agricultural and Biological Engineering, August 2011. (UF/IFAS Photo: Josh Wickham)
http://edis.ifas.ufl.edu/ae482
A Hister Beetle Carcinops pumilio (Erichson) (Insecta: Coleoptera: Histeridae: Dendrophilinae: Paromalini)
Authors: Moore Matthew R. , Kaufman Phillip E. 
Published: December 2020

Includes: Introduction - Taxonomy and Synonymy - Distribution - Description - Life Cycle - Ecology - Economic Importance - Medical and Veterinary Importance - Selected References
Also available on the Featured Creatures website at http://entnemdept.ufl.edu/creatures/beneficial/beetles/Carcinops_pumilio.htm
Dune Restoration and Enhancement for the Florida Panhandle
Authors: Miller Debbie L. , Thetford Mack , Verlinde Chris M. , Campbell Gabriel , Smith Ashlynn 
Published: December 2020

Published by the UF/IFAS Florida Sea Grant College Program, this manual provides an overview of the coastal ecosystems along the Florida Panhandle and shows how dunes can be restored and enhanced in this region of the Northern Gulf of Mexico.
In addition to direct experience acquired over many years of field work and experimentation, authors Chris Verlinde, Mack Thetford, and Debbie Miller consulted peer-reviewed academic journals, government documents, and various online resources to create the manual. Undergraduate and graduate students from the University of Florida and local professionals worked together with the UF/IFAS researchers to develop and test practical restoration techniques for Florida’s dunes. http://edis.ifas.ufl.edu/sg156
Weibull Probabilistic Model of Moisture Concentration Build Up in a Fiber Graphite/Epoxy Polymer Composite under Varying Hydrothermal Conditions
Authors: Belhadj Boucham , Abdelkader Lousdad , Chateauneuf Alaa 
Published: December 2020

Advanced mechanical and structural applications require accurate assessment and better knowledge of the damage state during elaboration and service. The development of life prediction methodologies for Glass Fiber Reinforced Polymers (GFRPs) has increased with the use of composites in different industries. It is important to develop through thickness degradation analyses due to ageing in order to predict its effect on the lifetime of composite structures. This study aims to model the moisture absorption, the concentration of the absorbed fluid and the reduction of mechanical properties in the through the thickness direction of a GFRPs structure. The water absorption behavior of woven glass fiber reinforced cyanate ester composites used in the plenum of the air conditioning pack of aircraft environmental control system has been modeled. The combined models describe the diffusion procedure primarily at material level and continuously at structure level. The amount of the absorbed moisture can be crucial for the mechanical behavior of the structure. Therefore, there is a need for a better understanding of the evolution of mechanical properties during ageing. The procedure utilizes the results of the diffusion model to calculate the moduli degradation during the water uptake process. Predictive models have been proposed by considering different sections throughout the thickness and provide a solid background for modeling the long term behavior of a structure exposed at different temperature and different time period. This work performed the numerical studies on the effect of moisture, temperature and presents some useful instructions for the evaluation of such composite structures.
In vitro Cytotoxic, Antioxidant and Antimicrobial Activities of Alcoholic and Chloroform Extracts of Dhofari Frankincense
Authors: Soliman Alaa M , Majeed Raniah R , Himyari Hala F Ali , UM Dhanalekshmi , Khan Shah A 
Published: December 2020

Omani (Dhofari) frankincense is world famous for its high quality and fragrance. The oleo-gum resin obtained from the tree of Omani species i.e., Boswellia sacra (local name: luban) is widely used by the natives. The aim of the study was to determine the presence of phytochemicals in chloroform and ethanol extracts of B. sacra resin and to evaluate the in vitro cytotoxic, antimicrobial- and antioxidant-activities. The ethanol and chloroform extracts of Hojari luban were obtained in good yield. The extracts were subjected to phytochemical screenings, quantification of total phenolics (TP) and evaluation of in vitro biological activities viz. antioxidant, antibacterial and cytotoxic potential. The bioactivities of four boswellic acids, the major constituents of the oleo-gum resin, were also predicted with the help of PASS and CLC-pred software. Both the extracts showed similar level of TP (14.67 mg/g and 14.79 mg/g in terms of gallic acid equivalent) but polar fraction was noted to be more active against E. coli. A moderate antioxidant activity was shown by the resin extracts however their cytotoxic activity was observed to be quite remarkable at 1000 μg/l which could be attributed to their high boswellic acid content. Results of in silico PASS studies showed boswellic acids to possess an array of useful biological activities including chemopreventive activity. Further, CLC-pred software revealed that only keto boswellic acid is expected to exert antineoplastic activity against pancreatic carcinoma cell lines, however all the four major boswellic acids are likely to be active against non-tumor embryonic lung fibroblast (MRC5). The study confirmed that frankincense is rich in bioactive metabolites which are of significant economic and therapeutic importance.
Dhaka Univ. J. Pharm. Sci. 19(2): 105-110, 2020 (December)
Evaluation of the Skeleton Avatar Technique for Assessment of Mobility and Balance Among Older Adults
Authors: Backåberg Sofia , Hellström Amanda , Fagerström Cecilia , Halling Anders , Lincke Alisa , Löwe Welf , Ekstedt Mirjam 
Published: December 2020

Background: Mobility and balance is essential for older adults' well-being and independence and the ability to maintain physically active. Early identification of functional impairment may enable early risk-of-fall assessments and preventive measures. There is a need to find new solutions to assess functional ability in easy, efficient, and accurate ways, which can be clinically used frequently and repetitively. Therefore, we need to understand how functional tests and expert assessments (EAs) correlate with new techniques.Objective: To explore whether the skeleton avatar technique (SAT) can predict the results of functional tests (FTs) of mobility and balance: Timed Up and Go (TUG), the 30-s chair stand test (30sCST), the 4-stage balance test (4SBT), and EA scoring of movement quality.Methods: Fifty-four older adults (+65 years) were recruited through pensioners' associations. The test procedure contained three standardized FTs: TUG, 30sCST, and 4SBT. The test performances were recorded using a three-dimensional SAT camera. EA scoring was performed based on the video recordings of the 30sCST. Functional ability scores were aggregated from balance and mobility scores. Probability theory-based statistical analyses were used on the data to aggregate sets of individual variables into scores, with correlation analysis used to assess the dependency between variables and between scores. Machine learning techniques were used to assess the appropriateness of easily observable variables/scores as predictors of the other variables included.Results: The results indicate that SAT data of the fourth 4SBT stage could be used to predict the aggregated results of all stages of 4SBT (with 7.82% mean absolute error), the results of the 30sCST (11.0%), the TUG test (8.03%), and the EA of the sit-to-stand movement (8.79%). There is a moderate (significant) correlation between the 30sCST and the 4SBT (0.31, p = 0.03), but not between the EA and the 30sCST.Conclusion: SAT can predict the results of the 4SBT, the 30sCST (moderate accuracy), and the TUG test and might add important qualitative information to the assessment of movement performance in active older adults. SAT might in the future provide the means for a simple, easy, and accessible assessment of functional ability among older adults.
Trends and prospects for the development of regional clusters’ capacity in a society's digitalization
Authors: Voynarenko Mykhaylo 
Published: December 2020

The tendencies of development of the world economy and its influence on structural and qualitative changes of regional cluster systems are analyzed. Globalization is characterized as one of the most powerful factors that determines the further development of socio-economic systems, promotes the interdependence of national economies and the creation of highly effective mechanisms for their integration into a single world economic space. The emphasis is on its inevitability and consequences for business entities. The role of clusters in international economic expansion and in combining the potential of science, business and the state to ensure socio-economic development of regions is shown. Transformation processes in cluster systems are systematized, periodicity of cluster structures development is considered, and their influence on regional development is established. International cluster is defined as an international integrated structure based on the interaction of legally independent enterprises of various industries focused on the global world market of resources and consumers that are combined by the introduction of modern technologies into all areas. The peculiarities of the digital economy manifestation, which is developing at an exponential rate and radically changing the essence of business, are highlighted. The preconditions, advantages and problem aspects of digitization of economic processes are outlined, its influence on the conditions of functioning and structural changes of cluster systems as the basis for the development of a new type of world economy is revealed. The paper reveals that regional economy clustering and digitalization should be targeted at overcoming the resistance to changes, being supported by independent scientific and technological research and having the cultural digital imperative to be successful in the model of digital transformation in global economic space.
FUZZY COGNITIVE MODELS IN MANAGEMENT OF SEMI-STRUCTURED SOCIO-ECONOMIC SYSTEMS
Authors: Захарова А.А. , Подвесовский А.Г. , Исаев Р.А. 
Published: December 2020

В статье рассматривается проблематика моделирования слабоструктурированных социально-экономических систем на основе применения когнитивного подхода. Предлагается авторская информационная технология поддержки когнитивного моделирования таких систем, основанная на использовании нечетких когнитивных карт. Описывается опыт применения предложенной технологии и реализующей ее программной системы при решении ряда практических задач исследования стратегий управления социально- экономическими системами.
The article deals with the problems of modeling semi-structured socio- economic systems based on the use of the cognitive approach. The original information technology for supporting the cognitive modeling of such systems based on the use of fuzzy cognitive maps is proposed. The experience of using the proposed technology and the software system that implements it in solving a number of practical problems of researching strategies for managing socio-economic systems is described.
INFORMATION COORDINATION OF THE NATIONAL ECONOMIC AND INDUSTRY MODELS ON THE EXAMPLE OF THE RUSSIAN FEDERATION FORESTRY
Authors: Стойлова А.С. , Машкина Л.В. , Блам Ю.Ш. 
Published: December 2020

Подход к моделированию, описанный в статье, позволяет на основе Оптимизационной Межрегиональной Межотраслевой Модели (ОМММ) сформировать отраслевую модель лесного комплекса производственно-транспортного типа. С помощью этой модели можно учесть заготовку и переработку лесного сырья, производство промежуточной и конечной продукции, действующие и новые мощности, нагрузку на лесной комплекс со стороны народного хозяйства, а также импорт, экспорт и транспортные связи между регионами. Переход от решения задачи на поиск максимума конечного потребления к задаче на нахождение минимума затрат на производство и перевод стоимостных показателей в натуральные позволяет привести модель к виду, наиболее подходящему для анализа отраслевых особенностей и прогнозирования развития лесного комплекса.
The modeling approach described in this article allows, on the basis of OIIM, to build the forestry industry model of the production-transport type. Using this model, it is possible to take into account the harvesting and processing of timber, the production of intermediate and final products, existing and new capacities, the load on the forest complex from the national economy, as well as import, export and transport links between regions. The transition from solving the problem of finding the maximum final consumption to the problem of finding the minimum cost of production and converting cost indicators into natural values allows to transform the model to the form most suitable for analyzing industry characteristics and predicting the development of the complex.
Plasma BCAA concentrations during exercise of varied intensities in young healthy men—the impact of endurance training
Authors: Gawedzka Anna , Grandys Marcin , Duda Krzysztof , Zapart-Bukowska Justyna , Zoladz Jerzy A. , Majerczak Joanna 
Published: December 2020

Background
Branched-chain amino acids (BCAA) i.e., leucine (Leu), isoleucine (Ile) and valine (Val) are important amino acids, which metabolism play a role in maintaining system energy homeostasis at rest and during exercise. As recently shown lowering of circulating BCAA level improves insulin sensitivity and cardiac metabolic health. However, little is known concerning the impact of a single bout of incremental exercise and physical training on the changes in blood BCAA. The present study aimed to determine the impact of a gradually increasing exercise intensity—up to maximal oxygen uptake (VO2max) on the changes of the plasma BCAA [∑BCAA]pl, before and after 5-weeks of moderate-intensity endurance training (ET).

Methods
Ten healthy young, untrained men performed an incremental cycling exercise test up to exhaustion to reach VO2max, before and after ET.

Results
We have found that exercise of low-to-moderate intensity (up to ∼50% of VO2max lasting about 12 min) had no significant effect on the [∑BCAA]pl, however the exercise of higher intensity (above 70% of VO2max lasting about 10 min) resulted in a pronounced decrease (p < 0.05) in [∑BCAA]pl. The lowering of plasma BCAA when performing exercise of higher intensity was preceded by a significant increase in plasma lactate concentration, showing that a significant attenuation of BCAA during incremental exercise coincides with exercise-induced acceleration of glycogen utilization. In addition, endurance training, which significantly increased power generating capabilities at VO2max (p = 0.004) had no significant impact on the changes of [∑BCAA]pl during this incremental exercise.

Conclusion
We have concluded that an exercise of moderate intensity of relatively short duration generally has no effect on the [∑BCAA]pl in young, healthy men, whereas significant decrease in [∑BCAA]pl occurs when performing exercise in heavy-intensity domain. The impact of exercise intensity on the plasma BCAA concentration seems to be especially important for patients with cardiometabolic risk undertaken cardiac rehabilitation or recreational activity.
Reduction of Malaria by Insecticide-Treated Mosquito Nets in Potiskum, Yobe State, Nigeria
Authors: Ali Audu , Bala Aminu Y. , Okwuonu Elijah S. , Orakwelu Chinemerem H. , Aguzie Ifeanyi O. 
Published: December 2020

Aims: The study was conducted to assess prevalence of malaria pre- and post-distribution of insecticide treated nets (ITNs) in Potiskum Local Government Area, Yobe State, Nigeria.
Study Design: Retrospective and cross-sectional.
Place of Study: Potiskum Local Government Area, Yobe State, Nigeria.
Materials and Methods: Prevalence of malaria infection in ten political wards pre-distribution of ITNs was investigated using secondary data sources from Roll Back Malaria and Integrated Disease Surveillance and Response offices. Thin and thick blood smears used to evaluate malaria prevalence post-distribution of ITNs were prepared from blood samples of 520 patients seeking medical attention from the General Hospital, Potiskum. Questionnaires were also handed out to the same set of patients.
Results: Prevalence of malaria infection pre- and post-distribution of ITNs in the study area was 57.9% and 22.9% respectively. Respondents to the questionnaire (n = 216) had mosquito nets, of whom 85% owned long-lasting ITNs and the remaining, conventional nets, but 35% used ITNs in their homes and 63% of those owning ITNs received them free-of-charge from local health centers.
Conclusion: If the impact of ITNs as an effective malaria vector control measure must be sustained, there should be a corresponding awareness program, which should be aimed at encouraging proper and constant use of ITNs.
Baseline Tryptase Levels Correlate with Baseline Basophil Levels in Chronic Myeloid Leukemia-Chronic Phase
Authors: Mathew Anisha , Naithani Manisha , Saha Sarama , Chetia Rituparna , Nath Uttam Kumar 
Published: December 2020

Aims: To study whether there is any correlation between baseline blood basophil count and serum tryptase levels in newly diagnosed chronic phase chronic myeloid leukemia (CML-CP) patients.
Settings and Design: 40 newly diagnosed CML-CP patients were enrolled from Medical Oncology Hematology OPD based on their baseline BCR-ABL status (done in department of Biochemistry).
Methods and Materials: Serum tryptase level was measured using Sandwich ELISA and peripheral blood basophil count was estimated using automated cell counter & peripheral blood film examination. BCR-ABL quantification was done using real time PCR after conversion of RNA (extracted from whole blood) to cDNA.
Statistical Analysis Used: SPSS Version 23.
Results: Baseline peripheral blood basophil levels showed a significant correlation with baseline serum tryptase levels (p<0.01) and tryptase level also correlated with EUTOS score, which has basophil count as one of the parameters. This may signify that serum tryptase levels can be a surrogate marker of the basophil compartment in CML-CP.
Conclusions: Based on findings of the present study and other studies available in literature, serum tryptase can be utilised as a surrogate marker of the basophil compartment in CML-CP.
Systemic Lupus Erythematosus Symptom Clusters and Their Association With Patient‐Reported Outcomes and Treatment: Analysis of Real‐World Data
Authors: Touma Zahi , Hoskin Ben , Atkinson Christian , Bell David , Massey Olivia , Lofland Jennifer H. , Berry Pamela , Karyekar Chetan S. , Costenbader Karen H. 
Published: December 2020

ObjectiveTo identify discrete clusters of systemic lupus erythematosus (SLE) patients based on symptoms and investigate differences across clusters.MethodsData were collected in the US and 5 European countries via the Adelphi Real World Lupus Disease Specific Programme, a cross‐sectional survey. Rheumatologists provided data for 5 consecutively consulting adult patients with SLE, who were invited to participate. Identified SLE symptoms were reduced to factors based on commonly concurrent symptoms, using principal‐component factor analysis. Factors were used as covariates in a latent‐class cluster analysis to identify discrete patient clusters. Patient‐reported outcomes and physician‐reported data were compared across clusters.ResultsAmong 1,376 patients, 87% were female and 74% were White. We identified 4 patient clusters (very mild, mild, moderate, and severe) based on 39 signs/symptoms. Physician‐reported symptom burden, organ involvement, disease activity, and the number of flares increased with increasing cluster severity (P < 0.0001). Patient‐reported impact (health status, fatigue, work productivity impairment, anxiety/depression, and emotional impact) increased with increasing cluster severity (P < 0.0001). Glucocorticoid and immunosuppressant use increased, and antimalarial use decreased, with increasing cluster severity. In all clusters, <20% of patients received biologics; >15% of patients not receiving biologics were considered eligible for treatment by their physician. The proportion of physicians and patients satisfied with treatment decreased with increasing cluster severity (P < 0.0001).ConclusionOur large, international, real‐world survey of SLE patients and physicians demonstrated strong associations between increased impairment, organ involvement, and humanistic burden in SLE, highlighting an unmet need for effective treatment options in patients with high disease activity.