bluuebunny/crossref_metadata_2025_split huggingface dataset:
CXCL8high inflammatory B cells in the peripheral blood of patients with biliary atresia are involved in disease progression
Authors: Zhang Yu , Zhou Lin , Gu Guangxiang , Feng Mingxuan , Ding Xuping , Xia Qiang , Lu Liming 
Published: June 2020

AbstractBiliary atresia (BA), the most common cause of pediatric end‐stage liver disease, results from fibroinflammatory obstruction of the intrahepatic and extrahepatic bile ducts. The etiology of BA has been extensively studied, and inflammation and imbalanced immune system have been identified as the main pathogenesis of BA. B cells play roles in innate and adaptive immunity, but few studies have investigated the role of B cells in BA. This study aimed to elucidate the role of B cells in the development of BA. The percentage and numbers of total B cells (23.81 ± 11.14%，P < 0.0001, 1.22 ± 0.67 × 109 L–1, P = 0.0014) and immature B cells (25.33 ± 14.32%, P = 0.0013, 0.19 ± 0.20 × 109 L–1, P < 0.0001) were significantly increased in the peripheral blood of patients with BA and the number of total B cells was positively correlated with gamma‐glutamyl‐transpeptidase in the serum of BA. High C–X–C motif chemokine ligand 8 (CXCL8) levels were detected in the serum of patients with BA. As an important source of CXCL8, B cells from patients with BA secreted more CXCL8 into peripheral blood than those from control patients. Moreover, immature B cells can secrete more CXCL8 than mature B cells, and B cells secreted CXCL8 upon activation of the nuclear factor‐κB pathway. Taken together, the results revealed that B cells have a strong ability to secrete CXCL8, which is associated with the pathogenesis of BA, and exert a proinflammatory effect on the development of BA.
Temperature stability of a pure metakaolin based K‐geopolymer: Part 2. Variations in the mesoporous network and its rehydration stability
Authors: Gomes Sandrine , Petit Elodie , Frezet Lawrence , Nedelec Jean‐Marie , Gharzouni Ameni , Rossignol Sylvie , Renaudin Guillaume 
Published: June 2020

AbstractThe thermal behavior of a model MK‐based K‐geopolymer was investigated between room temperature and 1400°C in order to evaluate its potentiality for high‐temperature applications. The purpose of our study was to monitor the behavior of a geopolymer during a temperature rise in order to better understand its variations with respect to temperature. The works from the present paper focus only changes in the porous network; it follows a first part devoted to variations in the mineral matrix. The results obtained here show that the geopolymer material preserves its porous integrity up to 800°C, while maintaining the reversibility of water exchanges corresponding to about 25 weight percent. Together with the results of part 1, the findings of this study allow us to affirm that geopolymer materials are only very little affected by temperatures up to 800°C, or even 900°C (keeping its mesoporous amorphous structure).
Hot Isostatically Pressed (HIPed) fluorite glass‐ceramic wasteforms for fluoride molten salt wastes
Authors: Gregg Daniel J. , Vance Eric R. , Dayal Pranesh , Farzana Rifat , Aly Zaynab , Holmes Rohan , Triani Gerry 
Published: June 2020

AbstractMolten pyroprocessing salts can be used to dissolve used nuclear fuel from a reactor allowing recovery of the actinides. Previously, ANSTO have demonstrated hot isostatically pressed (HIPed) sodalite glass‐ceramic wasteforms for eutectic (Li,K)Cl salts containing fission products, but this system cannot be used for the analogous molten alkali fluoride salts (eg, FLiNaK), which have utility in the application of the next generation of nuclear reactors. In this work, a novel glass‐ceramic composite wasteform has been prepared by HIPing, as a candidate for the immobilization of fission product‐bearing FLiNaK salts. The wasteform has been tailored to immobilize the high fluoride content of the waste within fluorite, whereas the waste alkali elements are incorporated in a durable sodium aluminoborosilicate glass, with total waste loadings of ~17‐21 wt% achieved. It was also demonstrated that the speciation of Mo‐ and Sb‐simulated fission products was altered by adding Ti metal due to a controlled redox environment. The resulting candidate wasteform has been studied by X‐ray diffraction and scanning electron microscopy, including the HIP canister‐wasteform interaction zone, and its performance assessed via leaching studies using the PCT and ASTM C1220 leaching protocols. Dr Vance very much enjoyed the challenge of wasteform design for problematic nuclear wastes, for which fission product‐bearing FLiNaK salts are a clear example. His ability to hone in on a wasteform solution with viable waste loadings that meet performance requirements was testament to his nearly 40 years experience in nuclear waste immobilization. The samples discussed in this work represent the last wasteform materials that he prepared.
Superheating nature coupled with Mg‐doping effect of high thermal stable NdBa2Cu3O7‐δ film
Authors: Yin Yiqian , Wan Yan , Huang Simin , Zhu Yanhan , Chen Ran , Tao Bowan , Rao Qunli , Zhou Difan , Yao Xin 
Published: June 2020

AbstractNdBa2Cu3O7‐δ thin film deposited on a MgO substrate has been verified to remain solid above its peritectic melting temperature (Tp). Such a superheating nature is attributed to its low energy surface and epitaxial interface with substrate. Here, combining superheating nature with doping effect, we report a novel structure, Mg‐doped NdBa2Cu3O7‐δ film with YBa2Cu3O7‐δ buffer layer for the first time. Remarkably, this film presents a higher thermal stability level than heretofore possible when acting as a seed for preparing SmBa2Cu3O7‐δ bulks by melt growth, enduring a temperature of 1128°C, 43 K above its Tp for 1 hour. The utilization of such a high Tmax in melt growth is beneficial to the fabrication of large‐sized and high‐performance bulk in terms of effectively broadening the growth window and suppressing the heterogeneous nucleation. More importantly, some high thermal stability required technological applications, such as batch growth and failed bulk recycling, are likely to be realized by this novel Mg‐doped NdBa2Cu3O7‐δ film seed. Finally, we show how the observed metastable phase is linked to the distinctive film architecture.
The sound absorption performance of the highly porous silica ceramics prepared using freeze casting method
Authors: Du Zhongpei , Yao Dongxu , Xia Yongfeng , Zuo Kaihui , Yin Jinwei , Liang Hanqin , Zeng Yu‐Ping 
Published: June 2020

AbstractHighly porous silica ceramics with unidirectional pores were prepared using the freeze casting method. By adjusting the solid content and freezing temperature, the porosity of the ceramics was tailored in the range of 78.20%‐84.59% and pore size in the range of 8.4‐71.4 μm, respectively. Sound absorption properties of porous silica ceramics was studied and the effect of structural factors was systematically investigated. The results showed that higher porosity and smaller pores of the porous ceramics favored the sound absorption in the entire sound wave frequency. By backing the sample with small pore size porous ceramics, the sound absorption property was enhanced, particularly in the low and medium frequency range, thus the sound absorption peak shifted towards lower frequency. The presence of air gap in the back would also favor sound absorption in low and medium frequency range. The as‐fabricated porous silica ceramics owed excellent sound absorption properties due to their unidirectional pores and low flow resistances.
Dielectric properties of polymer‐derived ceramic reinforced with boron nitride nanotubes
Authors: Jia Yujun , Ajayi Tosin D. , Xu Chengying 
Published: June 2020

AbstractThe electrical and dielectric properties of boron nitride nanotubes (BNNTs) reinforced ceramic composites using the polymer‐derived ceramic (PDC) processing route were investigated in this work. The electrical resistivity of the pristine PDC increases from 106 to 108 Ω m after the addition of BNNTs. When the BNNT loading was increased to 5 wt%, the average real relative permittivity of the PDC decreased from 2.94 to 2.80, while the quality factor (Q) of the PDC increased from 134.40 to 176.77. The BNNTs can increase the Q factor of the PDC due to the reduction in the porosity cause by the introduction of the BNNTs. Further increasing the BNNT content decreases the real relative permittivity of the nanocomposites and increases the Q factor at high frequency. The average real relative permittivity decreases to 2.29, while the average Q factor increases to 208.60 when the BNNT content is increased to 30 wt%. The dielectric loss after the addition of high fraction of BNNTs can be explained by the Lorentz resonance relaxation process. Results of this work showed that PDC‐BNNT nanocomposites are satisfactory electromagnetic transparent materials when the BNNT fraction is less than 10 wt%.
Direct ink writing of hierarchical porous alumina‐stabilized emulsions: Rheology and printability
Authors: Chan Shareen S. L. , Sesso Mitchell L. , Franks George V. 
Published: June 2020

AbstractBio‐inspired multi‐scaled (hierarchical) porous structures have remarkable strength and stiffness‐to‐density properties. Direct ink writing (DIW) or robocasting, an additive manufacturing (or also commonly known as 3D printing) material extrusion technique is able to create near‐net‐shaped complex geometries. A new approach of combining DIW, colloidal particle‐stabilized emulsion paste inks and partial densification to create tailored architectures of hierarchical porosity on three scales has been demonstrated. The printed and sintered ceramic lattice structures possess relatively high overall porosity of 78.7% (on average), comprising mainly (64.7%) open porosity. The effects of formulation (surfactant and oil concentrations, solids particle size, and mixing speed) on rheology and pore size and morphology have been investigated. The rheological properties (storage modulus, yield stress, and recovery of storage modulus) of the emulsions have been found to delineate the samples with good shape retention from those that slump. Additionally, the internal features of the sintered structures have been analyzed via X‐ray tomography and scanning electron microscope. The role of emulsion stability on printability and the internal structure of the prints has been investigated.
The mediating role of locus of control between social resource stability and psychological well‐being
Authors: Strong Shelby L. , Gore Jonathan S. 
Published: June 2020

AbstractPast research has shown that social resources and locus of control are strongly linked to well‐being, but most research has focused on the amount rather than the stability of those resources. The goal of this study was to investigate the mediating role that locus of control had on the relationship between social resource stability and psychological well‐being. All three studies measured social resources and well‐being through online surveys (Studies 1 and 2 through SONA, and Study 3 through Mechanical Turk). Study 1 (n = 298 college students) demonstrated that social resource stability predicted lower psychological distress, while controlling for social resource amount. Study 2 (n = 300 college students) revealed that social resource stability predicted higher subjective well‐being, while controlling for social resource amount, and that locus of control mediated the association. Study 3 (n = 346 working adults) replicated the findings of Studies 1 and 2 using a nonacademic sample and alternative measures of well‐being.
Opioid training development: Cultivating nurse competence through education
Authors: Seney Valerie , Insana Jacqueline , Alberto Allison , Hay Jessica 
Published: June 2020

AbstractTopicMental illness and substance use have become areas of concern throughout society. One of the greatest concerns affecting the United States is the increased prevalence of opioid use and accidental overdose. The opioid epidemic not only impacts adults, it also affects the nation's most vulnerable youth. Children and adolescents are at high risk for substance abuse due to multiple risk factors including negative life events, family dysfunction, and parental substance abuse.PurposePediatric nurses must be prepared to care for children and families who experience opioid addiction and overdose. The aim of the quality improvement project was to improve the skill set of nurses working with children and adolescents with substance use disorders (SUDs) in a pediatric psychiatric hospital.Sources UsedNurses attended a 2‐hr workshop focused on nursing interventions related to SUD utilizing Orlando's Nursing Theory and Brief Intervention Therapy. Following the workshop, nurses reported their perceived competence in caring for individuals at risk for or identified with SUD increased.ConclusionThe workshop appeared to be effective in increasing nurses' competence and confidence if working with youth and their families dealing with substance use issues.
Conduction gap mapping of linear ablation lesions with high‐density mapping
Authors: Nakai Kentaro , Kashiwa Asami , Kunitomi Akira , Matsuoka Shunzo 
Published: June 2020

AbstractIntroductionWhen performing linear ablation, creating contiguous and transmural lesions are technically challenging due to the difficulty in finding electrical conduction gaps. We hypothesized that high‐density mapping could identify the gaps.Methods and ResultsThis study included consecutive patients who underwent conduction gap mapping of de novo lesions (41 patients, 55 lines) and previous lesions (25 patients, 34 lines). We analyzed the utility of bipolar and unipolar conduction gap mapping and retrospectively assessed the voltage and morphology of the bipolar electrograms at the gap sites. Bipolar and unipolar propagation maps were classified into three types: the propagation wavefront traveled through the linear ablation lesions (direct leak), the wavefront jumped to an opposite site across the line and returned to the line (jump and return leak), and others (indefinite leak). In the jump and return leak maps, the site where it returned suggested a conduction gap site. Bipolar propagation maps identified 30 (54.5%) conduction gaps and unipolar maps identified 40 (72.7%) gaps at de novo linear ablation lesions (P = .01), and 32 (94.1%) gaps and 33 (97.1%) gaps, respectively, at previous lesions (P = .56). Bipolar voltage mapping did not add any further efficacy in detecting conduction gaps, and the morphology of the electrograms recorded at the gap sites was not related to the types of propagation maps.ConclusionConduction gaps of linear ablation lesions can be visualized by high‐density mapping with a high probability. Unipolar propagation, when used with bipolar mapping, may help detect conduction gap sites.
Validity of anthropometric indices in predicting high blood pressure risk factors in Iranian children and adolescents: CASPIAN‐V study
Authors: Yazdi Mayram , Assadi Farahnak , Qorbani Mostafa , Daniali Seyede Shahbanoo , Heshmat Ramin , Esmaeil Motlagh Mohammad , Kelishadi Roya 
Published: June 2020

AbstractAnthropometric indices have been used as indicators for predicting hypertension (HTN) in children and adolescents but it is not clear which anthropometric measures are a better index for identifying elevated blood pressure (EBP) risk factors in pediatric population. Body mass index (BMI), waist circumference (WC), weight‐height ratio (WHR), a body shape index (ABSI) and blood pressure were measured in 14 008 children and adolescents aged 7‐18 years in a national school‐aged survey CASPIN V. Hypertension (HTN) was defined according to the 2017 American Academy of Pediatrics guidelines, using the 95th percentile. The predictive power of anthropometric indices for HTN risk factors was examined using receiver operating characteristic (ROC) analyses. Multivariate logistic regression analysis was used to compare areas under ROC curves (AUCs) among the four anthropometric indices. BMI, WC, WHR, and ABSI were significantly higher in adolescents than in children. EBP was more prevalent in boys (7.2%) than girls (5.5%), whereas the prevalence of HTN was higher in girls (11.3%) than boys 10.4%. Prevalence odds ratio was around 2 for BMI, WC, and WHR with AUCs scores of nearly 0.6 to predict EBP in both children and adolescents of both sexes. Thus, the ability of BMI z‐score, WC, WHR or ASBI to identify Iranian children and adolescents at higher risk of EBP was week. WC, WHR or ASBI in combination with BMI did not improve predictive power to identify subjects at higher risk of EBP.
Food intake and dietary patterns that affect urinary sodium excretion in young women
Authors: Yasutake Kenichiro , Imai Katsumi , Abe Shimako , Iwamoto Masako , Kawate Hisaya , Moriguchi Ririko , Ono Misaki , Ueno Hiromi , Miya Mana , Tsuda Hiroko , Nakano Shuji 
Published: June 2020

AbstractWe aimed to clarify food intake and dietary patterns that affect urinary sodium excretion (urinary salt excretion) among young women. We used 2012 to 2018 data from the health and nutrition testing on admission, which is a part of ongoing epidemiological studies, for students enrolling in the Faculty of Nutrition Science, Nakamura Gakuen University. Fasting urine samples were collected from the participants, and their estimated daily salt excretion was calculated using the Tanaka equation. The dietary assessment used was the semi‐quantitative food frequency questionnaire, and we confirmed its validity. The participants included 2218 women aged 18 to 20 years who were classified into four groups according to urinary salt excretion (g/d) from their spot urine: Q1, <5.56; Q2, 5.56≤, <6.79; Q3, 6.79≤, <8.12; and Q4, 8.12<. The high urinary salt group had a significantly higher consumption of oil and fat, fish, meat, eggs, soybean, green and yellow vegetables, white vegetables, seaweeds, and pickled vegetables compared with the low urinary salt groups. When we compared the differences of the quartiles for urinary sodium excretion and the factor loadings for three dietary patterns by factor analysis with varimax rotation, the high urinary salt group showed a higher tendency for Japanese dietary patterns of factor 1 compared with the low urinary salt group. In conclusion, the various foods, including foods containing proteins and vegetables and Japanese dietary pattern centering on fish, vegetables, soybeans, and seaweed, affected the urinary sodium excretion in young women.
Low‐density lipoprotein cholesterol : high‐density lipoprotein cholesterol ratio is associated with incident diabetes in Chinese adults: A retrospective cohort study
Authors: Wei Limin , Wei Meng , Chen Lei , Liang Shanshan , Gao Fanfan , Cheng Xin , Jiang Hongli 
Published: June 2020

AbstractAims/IntroductionDyslipidemia plays a critical role in the pathogenesis of metabolic syndrome and diabetes. Evidence has increasingly shown that the ratio of low‐ to high‐density lipoprotein cholesterol (LDL‐C/HDL‐C) is a novel marker for increased risk of insulin resistance and cardiovascular diseases. However, the correlation between the LDL‐C/HDL‐C ratio and diabetes risk is rarely reported. This is the first study to investigate the association between the LDL‐C/HDL‐C ratio and new‐onset diabetes in a large community‐based cohort.Materials and MethodsIn this retrospective cohort study, a total of 116,661 adults without baseline diabetes were enrolled. Participants were stratified into four groups based on LDL‐C/HDL‐C ratio quartiles. The outcome of interest was new‐onset diabetes.ResultsDuring a median follow‐up period of 2.98 years, 2,681 (2.3%) new diabetes cases were recorded. The total cumulative incidence of diabetes progressively increased alongside LDL‐C/HDL‐C ratio quartiles (0.31, 0.43, 0.68 and 0.88%, respectively, P‐value for trend <0.001). After adjusting for potential confounders, using the lowest quartile of the LDL‐C/HDL‐C ratio as the reference, the risk of diabetes increased with LDL‐C/HDL‐C ratio quartiles (P‐value for trend <0.001); in particular, from the second to fourth quartile, hazard ratios were 1.18 (95% confidence interval 0.87–1.59), 1.42 (95% confidence interval 1.07–1.90) and 1.92 (95% confidence interval 1.43–2.59), respectively. The results were also robust to challenges in multiple sensitivity analyses.ConclusionsAmong the Chinese population, elevated LDL‐C/HDL‐C ratio might be an independent risk factor for new‐onset diabetes.
Risk factors for new‐onset diabetes mellitus after kidney transplantation: A systematic review and meta‐analysis
Authors: Xia Mancheng , Yang Haosen , Tong Xunan , Xie Hongjie , Cui Fan , Shuang Weibing 
Published: June 2020

AbstractAims/IntroductionTo systematically review the risk factors for new‐onset diabetes mellitus after kidney transplantation, and to provide a theoretical basis for the prevention and management of new‐onset diabetes mellitus after kidney transplantation.Materials and MethodsWe searched PubMed, Web of Science, Embase, the Cochrane Library databases and other databases for case–control studies related to risk factors for new‐onset diabetes mellitus after kidney transplantation published between January 2005 and July 2019. A meta‐analysis of data on risk factors for new‐onset diabetes mellitus after kidney transplantation from the included studies was carried out. A narrative review of risk factors for new‐onset diabetes mellitus after kidney transplantation was also carried out.ResultsA total of 24 case–control studies were included in the meta‐analysis, with a total of 7,140 patients. There were 1,598 patients with new‐onset diabetes mellitus after kidney transplantation, and 5,542 patients without new‐onset diabetes mellitus after kidney transplantation. The meta‐analysis results showed that age, polycystic kidney disease, family history of diabetes, body mass index, acute rejection, tacrolimus use, hepatitis B virus infection, hepatitis C virus infection and hypertension were associated with new‐onset diabetes mellitus after kidney transplantation, whereas sex, sirolimus use, cyclosporin A use, steroid use and cytomegalovirus infection were not associated with new‐onset diabetes mellitus after kidney transplantation.ConclusionsOlder age, body mass index, family history of diabetes, tacrolimus use, history of hypertension, polycystic kidney disease, acute rejection, hepatitis B virus infection and hepatitis C virus infection are risk factors for new‐onset diabetes mellitus after kidney transplantation. Therefore, the clinical implications of these factors warrant attention.