bluuebunny/crossref_metadata_2025_split huggingface dataset:
Registered nurses' perspectives on medically safe practices and sound ethical standards in aesthetic nursing: An interview study
Authors: Holmberg Christopher , Carlström Eric , Collier Helena 
Published: December 2019

AbstractAims and objectivesTo explore the views of registered nurses experienced in aesthetic nursing regarding medically safe practices and sound ethical standards.BackgroundAesthetic nursing is an emerging field of modern‐day healthcare encompassed within aesthetic medicine. There is a distinct lack of research regarding how registered nurses who specialise in this area of care view medically safe practices and sound ethical standards. This is important to explore, because, in the absence of mandatory regulations within the sector, and it is the aesthetic nurse's own obligation to uphold professional, medical and ethical standards.DesignQualitative study.MethodsIndividual semi‐structured interviews were conducted with 13 registered nurses who had worked in aesthetic nursing for at least two years. The interview transcripts were categorised using qualitative content analysis. The COREQ checklist was used to report the study.ResultsA main theme was generated during the analysis: Considering my professional, the clinic's and the patient's needs. The participants described that they considered medical and ethical aspects pertinent to their professional roles as registered nurses but also undertook practices in addition to what they already did as registered nurses, such as creating professional networks using social media. They also described the importance of establishing local medical and ethical guidelines for their clinics, and that they considered patients’ individual needs such as using individual information relating to their patients’ previous experiences.ConclusionsThe study points to the positive tendencies of registered nurses in aesthetics to develop their own professional networks and create local medical and ethical guidelines until more robust mandatory regulations are in place.Relevance to clinical practiceConsidering that aesthetic nursing is a young industry, registered nurses are in an excellent position to utilise their professional networks and work with professional bodies to develop standards of professional nursing practice and education for this field.
Contribution to a public good under subjective uncertainty
Authors: Banerjee Anwesha , Gravel Nicolas 
Published: December 2019

AbstractThis paper examines how voluntary contributions to a public good are affected by the contributors' heterogeneity in beliefs about the uncertain impact of their contributions. It assumes that contributors have Savagian preferences that are represented by a two‐state‐dependent expected utility function and different beliefs about the benefit that will result from the sum of their contributions. We establish general comparative statics results regarding the effect of specific changes in the distribution of beliefs on the (unique) Nash equilibrium provision of the public good, under certain conditions imposed on the preferences. We specifically show that the equilibrium public good provision is increasing with respect to both first‐ and second‐order stochastic dominance changes in the distribution of beliefs. Hence, increasing the contributors' optimism about the uncertain benefit of their contributions increases aggregate public good provision, as does any homogenization of these beliefs around their mean.
An Integrated Approach for Modeling Sustainability Risks in Freight Transportation Systems
Authors: Choudhary Divya , Shankar Ravi , Choudhary Alok 
Published: December 2019

AbstractIntegrating sustainability into freight transportation systems (FTSs) is a complex and challenging task due to the sheer number of inherent sustainability risks. Sustainability risks disrupt the economic, social and environmental objectives of freight operations and act as impediments in the development of sustainable freight transportation systems. The area of sustainability risk management is still unexplored and immature in the operational research domain. This study addresses these research gaps and contributes in a threefold manner. First, a total of 36 potential sustainability risks related to FTSs are identified and uniquely classified into seven categories using a rigourous approach. Second, the research proposes two prominent perspectives, namely, ontological and epistemological perspectives to understand risks and develops a novel framework for managing sustainability risks in FTSs. Third, a novel approach by integrating fuzzy evidential reasoning algorithm (FERA) with expected utility theory is developed to quantitatively model and profile sustainability risk for different risk preferences, namely, risk‐averse, risk‐neutral, and risk‐taking scenarios. The proposed FERA is a flexible and robust approach, which transforms the experts’ inputs into belief structures and aggregates them using the evidence combination rule proposed in Dempster–Shafer theory to overcome the problem of imprecise results caused by average scoring in existing models. A sensitivity analysis is conducted to demonstrate the robustness of the proposed model. Unlike conventional perception, our study suggests that most of the high priority sustainability risks are behaviorally and socially induced rather than financially driven. The results provide significant managerial implications including a focus on skills development, and on social and behavioral dimensions while managing risks in FTSs.
Mechanisms underlying the stimulatory effect of inhaled sulfur dioxide on vagal bronchopulmonary C‐fibres
Authors: Lin An‐Hsuan , Hsu Chun‐Chun , Lin You Shuei , Lin Ruei‐Lung , Lee Lu‐Yuan 
Published: December 2019

Key points
Brief inhalation of SO2 of concentration >500 p.p.m. triggered a pronounced stimulatory effect on vagal bronchopulmonary C‐fibres in anaesthetized rats.
This stimulatory effect was drastically diminished by a pretreatment with NaHCO3 that raised the baseline arterial pH, suggesting a possible involvement of acidification of airway fluid and/or tissue generated by inhaled SO2.
The stimulation was completely abolished by pretreatment with antagonists of both acid‐sensing ion channels and transient receptor potential vanilloid type‐1 receptors, indicating that this effect was caused by acid activation of these cation channels expressed in airway sensory nerves.
This conclusion was further supported by the results obtained from studies in isolated rat vagal bronchopulmonary sensory neurones and also in the cough response to SO2 inhalation challenge in awake mice.
These results provide new insight into the underlying mechanism of harmful irritant effects in the respiratory tract caused by accidental exposure to a high concentration of SO2.
AbstractInhalation of sulfur dioxide (SO2) triggers coughs and reflex bronchoconstriction, and stimulation of vagal bronchopulmonary C‐fibres is primarily responsible. However, the mechanism underlying this stimulatory effect is not yet fully understood. In this study, we tested the hypothesis that the C‐fibre stimulation was caused by SO2‐induced local tissue acidosis in the lung and airways. Single‐unit activities of bronchopulmonary C‐fibres in response to inhalation challenges of SO2 (500–1500 p.p.m., 10 breaths) were measured in anaesthetized rats. Inhalation of SO2 reproducibly induced a pronounced and sustained stimulation (lasting for 15–60 s) of pulmonary C‐fibres in a concentration‐dependent manner. This stimulatory effect was significantly attenuated by an increase in arterial pH generated by infusion of sodium bicarbonate (NaHCO3), and completely abrogated by a combined pretreatment with amiloride (an antagonist of acid‐sensing ion channels, ASICs) and AMG8910 (a selective antagonist of the transient receptor potential vanilloid type‐1 receptor, TRPV1). Furthermore, in isolated rat vagal pulmonary sensory neurones, perfusion of an aqueous solution of SO2 evoked a transient increase in the intracellular Ca2+ concentration; this response was also markedly diminished by a pretreatment with amiloride and AMG8910. In addition, inhalation of SO2 consistently evoked coughs in awake mice; responses were significantly smaller in TRPV1−/− mice than in wild‐type mice, and almost completely abolished after a pretreatment with amiloride in TRPV1−/− mice. These results suggested that the stimulatory effect of inhaled SO2 on bronchopulmonary C‐fibres was generated by acidification of fluid and/or tissue in the lung and airways, which activated both ASICs and TRPV1 expressed in these sensory nerves.
Investigation of Numerical Evaluation Improvement for Three-Dimensional Infinite Cylindrical Heat Conduction Problems
Authors: Pi Te , Cole Kevin , Zhao Qingjun , Zhao Wei 
Published: December 2019

Abstract
To estimate the thermal properties from transient data, a model is needed to produce numerical values with sufficient precision. Iterative regression or other estimation procedures must be applied to evaluate the model again and again. From this perspective, infinite or semi-infinite heat conduction problems are a challenge. Since the analytical solution usually contains improper integrals that need to be computed numerically, computer-evaluation speed is a serious issue. To improve the computation speed with precision maintained, an analytical method has been applied to three-dimensional (3D) cylindrical geometries. In this method, the numerical evaluation time is improved by replacing the integral-containing solution by a suitable finite body series solution. The precision of the series solution may be controlled to a high level and the required computer time may be minimized by a suitable choice of the extent of the finite body. The practical applications for 3D geometries include the line-source method for obtaining thermal properties, the estimation of thermal properties by the laser-flash method, and the estimation of aquifer properties or petroleum-field properties from well-test measurements. This paper is an extension of earlier works on one-dimensional (1D) and two-dimensional (2D) cylindrical geometries. In this paper, the computer-evaluation time for the finite geometry 3D solutions is shown to be hundreds of times faster than the infinite or semi-infinite solution with the precision maintained.
Partial Differential Equation-Based Trajectory Planning for Multiple Unmanned Air Vehicles in Dynamic and Uncertain Environments
Authors: Radmanesh Mohammadreza , Kumar Manish , French Donald 
Published: December 2019

Abstract
This paper proposes a physics-inspired method for unmanned aerial vehicle (UAV) trajectory planning in three dimensions using partial differential equations (PDEs) for application in dynamic hostile environments. The proposed method exploits the dynamical property of fluid flowing through a porous medium. This method evaluates risk to generate porosity values throughout the computational domain. The trajectory that encounters the highest porosity values determines the trajectory from the point of origin to the goal position. The best trajectory is found using the reaction of the fluid in porous media by the way of streamlines obtained by numerically solving the PDEs representing the fluid flow. Constraints due to UAV dynamics, obstacles, and predefined way points are applied to the problem after solving for the best trajectory to find the optimal and feasible trajectory. This method shows near-optimality and much reduced computational effort when compared to the other typical numerical optimization methods.
Biomechanical Comparison of Real World Concussive Impacts in Children, Adolescents, and Adults
Authors: Dawson Lauren , Koncan David , Post Andrew , Zemek Roger , Gilchrist Michael D. , Marshall Shawn , Hoshizaki T. Blaine 
Published: December 2019

Abstract
Accidental falls occur to people of all ages, with some resulting in concussive injury. At present, it is unknown whether children and adolescents are at a comparable risk of sustaining a concussion compared to adults. This study reconstructed the impact kinematics of concussive falls for children, adolescents, and adults and simulated the associated brain tissue deformations. Patients included in this study were diagnosed with a concussion as defined by the Zurich Consensus guidelines. Eleven child, 10 adolescent, and 11 adult falls were simulated using mathematical dynamic models(MADYMO), with three ellipsoid pedestrian models sized to each age group. Laboratory impact reconstruction was conducted using Hybrid III head forms, with finite element model simulations of the brain tissue response using recorded impact kinematics from the reconstructions. The results of the child group showed lower responses than the adolescent group for impact variables of impact velocity, peak linear acceleration, and peak rotational acceleration but no statistical differences existed for any other groups. Finite element model simulations showed the child group to have lower strain values than both the adolescent and adult groups. There were no statistical differences between the adolescent and adult groups for any variables examined in this study. With the cases included in this study, young children sustained concussive injuries at lower modeled brain strains than adolescents and adults, supporting the theory that children may be more susceptible to concussive impacts than adolescents or adults.
Anisotropic Diffusivity Tensor in Articular Cartilage: Effective Medium Approach
Authors: Hashlamoun Kotaybah , Federico Salvatore 
Published: December 2019

Abstract
Due to the avascular nature of articular cartilage, molecular transport occurs via interstitial fluid flow as well as via diffusion. Diffusion in cartilage has been studied experimentally, but no mathematical models have been developed to interpret the experimental results and the observed isotropy or anisotropy in the different cartilage zones. Here, we propose a model for the determination of the diffusivity tensor of uncharged macromolecules in articular cartilage, accounting for the inhomogeneity and anisotropy arising from fiber arrangement, volumetric fraction, and radius. We study a representative element of volume (REV) comprising a fiber surrounded by fluid-saturated proteoglycan matrix. The REV permeability tensor is evaluated using a previously developed model, while the REV diffusivity tensor is obtained by incorporating the hydrodynamic effect and the steric effect of the fiber-reinforced matrix. Both effects are represented by anisotropic second-order tensors. The overall diffusivity tensor is obtained as the averaging integral of the REV diffusivity, weighted by the probability distribution of fiber orientation. The model's predictions of the trend of the magnitude of the diffusivity of spheroidal macromolecules as a function of molecular radius agree with published experimental results. For large linear macromolecules, the model underestimates the diffusivity magnitude (i.e., the equivalent isotropic diffusivity). The model correctly predicts the anisotropic behavior for linear macromolecules, although it underestimates the numerical value of the diffusivity anisotropy ratio of large linear macromolecules in the superficial zone, and overestimates it in the deep zone. In summary, this model constitutes a first step toward understanding the relation between diffusivity and permeability in articular cartilage.
Ankle Control in Walking and Running: Speed- and Gait-Related Changes in Dynamic Mean Ankle Moment Arm
Authors: Adamczyk Peter Gabriel 
Published: December 2019

Abstract
The human foot–ankle complex uses heel-to-toe ground contact progression in walking, but primarily forefoot contact in high-speed running. This qualitative change in ankle control is clear to the runner, but current measures of ankle behavior cannot isolate the effect, and it is unknown how it changes across moderate speeds. We investigated this dynamic ankle control across a range of walking and running speeds using a new measure, the dynamic mean ankle moment arm (DMAMA): the ratio of sagittal ankle moment impulse to ground reaction force impulse on a single limb. We hypothesized that DMAMA would increase with speed in both walking and running, indicating more forefoot-dominated gait with ground reaction forces more anterior to the ankle. Human subjects walked (1.0–2.0 m/s) and ran (2.25–5.25 m/s) on an instrumented treadmill with motion capture and pressure insoles to estimate DMAMA. DMAMA decreased with increasing walking speed, then increased upon the transition to running, and increased further with increasing running speed. These results provide quantitative evidence that walking becomes more hindfoot-dominated as speed increases—similar to behavior during acceleration—and that running is more forefoot-dominated than walking. The instantaneous center of pressure (COP) at initial ground contact did not follow the same trends. The discrepancy highlights the value of DMAMA in summarizing ankle control across the whole stance phase. DMAMA may provide a useful outcome metric for evaluating biomimetic prostheses and for quantifying foot contact styles in running.
Design of a Novel Locking Ratcheting Mechanism for a Body-Powered Underactuated Hand
Authors: Lee Hun Chan , Cipra Raymond 
Published: December 2019

AbstractAs affordable and efficient three-dimensional (3D) printers became widely available, researchers are focusing on developing prosthetic hands that are reasonably priced and effective at the same time. By allowing anyone with a 3D printer to build a body-powered prosthetic hand, many people could build their own prosthetic hand. However, one of the major problems with the current designs is the users must bend and hold their wrist in an awkward position to grasp an object. The primary goal of this work is to present the design process and analysis of a body-powered underactuated prosthetic hand with a novel ratcheting mechanism that locks the finger automatically at a desired position. To estimate how a compliant finger behaves on the actual system with the ratcheting mechanism, the preshaping analysis and the preshaping experiment were conducted. From the experiment, the presence of elastic hysteresis was observed. Additionally, the contact force analysis was performed to see the effects of joint angles and applied tension force. To test how well the hand can grasp, a cup with various weights was lifted and various objects with different shapes were grasped to prove how well the compliant finger can adapt to the shape of the objects. Based on the experiment, the hand had a higher success rate of grasping objects that are lightweight (less than 500 g) and cylindrical or circular shaped.
Sustainable Development: A Below-Knee Prostheses Liner for Resource Limited Environments
Authors: Sasaki Kazuhiko , Guerra Gary , Rattanakoch Jutima , Miyata Yusuke , Suntharalingam Sharmila 
Published: December 2019

AbstractThis research sought to develop a fabricable prosthetic liner that could be fabricable, intuitive, and a cost-effective means of providing advanced prosthetics in developing settings. An affordable ethyl-vinyl-acetate roll-on (AERO) liner for permitting a total surface bearing suction socket design was created and provided to a single participant for in vivo outcome measurements. The liner was fabricated from locally produced low-density ethyl-vinyl-acetate (EVA) foam. A liner fabrication process was developed and described, and one participant was provided 3 mm and 6 mm AERO liner variants for outcome evaluations. Six-minute walk test, residual limb temperature, and socket comfort score (SCS) while in AERO liner were collected. Thirty-day step counts of AERO liner with prosthesis and thermoplastic elastomer (TPE) liner with prosthesis were collected. The results of in vivo evaluations indicate increased speed, slightly higher residuum temperature, and increased comfort of the 6 mm AERO liner. Pedometer tallied step counts for the AERO liner and TPE liner prostheses were similar. The 6 mm AERO liner provided the best comfort and function of the two thicknesses in liners, and step count data indicated that the volume of patient activity was similar to when wearing the TPE liner prosthesis. Roll-on fabricable low-cost liners offer an affordable means of providing total surface bearing suction prostheses for resource limited environments (RLE). A prosthetist or technician can use the existing skills and lab to create liners.
Functional Requirements and Quality Assurance Necessary for Successful Incorporation of Electroporation-Based Therapies Into Clinical Practice
Authors: Pirc Eva , Reberšek Matej , Miklavčič Damijan 
Published: December 2019

Abstract
Electroporation-based therapies have a huge potential for implementation into clinical practice in socioeconomically disadvantaged populations. Currently, the price of electroporators and electrodes is relatively high, but custom low budget devices can be developed. In the paper, we describe three most established applications in medicine, with the focus on the basic mechanisms, which should be taken into account during the development process of a clinical electroporator. Also, typical pulse parameters used in each of the described applications are defined. In the second part of the paper, we describe technical functional requirements for a clinical electroporator and safety guidelines, with the focus on medical device standard. At the end of the paper, the focus moves to a more general problematic, such as quality assurance and the importance of measurement during the pulse delivery, which we firmly believe is necessary for successful electroporation.
Experimental Analysis of Gas–Liquid Flows in a Centrifugal Rotor
Authors: Stel Henrique , Ofuchi Edgar M. , Alves Rafael F. , Chiva Sergio , Morales Rigoberto E. M. 
Published: December 2019

Abstract
This work presents an experimental analysis of gas–liquid flows in a centrifugal rotor prototype. Pressure rise curves are evaluated considering a wide range of liquid and gas flowrates and different rotating speeds. An innovative apparatus including a dynamic sealing system, back illumination, and filming in a rotating frame of reference is employed to visualize gas–liquid flow patterns at different operating conditions. Volume fraction measurement and bubble-size evaluation are also taken into account. The experimental apparatus allowed analyzing details of the gas-phase dynamics inside the rotor channels. That includes preferential bubble paths and zones of agglomeration, gas pocket formation, coalescence and breakup, and the effect of flow pattern transition on different degrees of performance degradation that centrifugal rotors are subject to when working with gas–liquid flows. Also, important information about the effect of the gas flowrate and the rotating speed on the performance of the assumed rotor prototype could be gathered. Discussions in this work should contribute to comprehend the behavior of gas–liquid flow in centrifugal pumps, a topic that is still far from being well understood. Qualitative and quantitative data here presented could also be valuable to guide the development of numerical models to solve this problem.