bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Variable Conductance on Heat and Mass Transport Mechanism Using Generalized Theory
Authors: Qureshi Imran Haider , Elmoasry Ahmed , Alebraheem Jawdat , Nawaz M. 
Published: June 2020

Abstract
Fourier law of heat conduction, its analog Fick's first law, and Newton's law of viscosity are classical laws that are not capable of exhibiting memory effects. Conservation laws based on these classical laws do not give predictions about memory effects on the transport phenomena. Recently, proposed novel laws are called Cattaneo–Christov heat flux. Models are based on the generalization of classical laws of heat conduction, mass diffusion, and Newton's law of viscosity. This investigation considers this generalized theory to model the impact of relaxation phenomenon on the transport of momentum, heat, and mass in Maxwell fluid (viscoelastic fluid) of temperature-dependent viscosity and thermal conductivity in the presence of temperature-dependent mass diffusion coefficients. It is observed from the simulations that memory effects play a key role in controlling momentum, thermal and concentration boundary layer thicknesses. It is also noted that the rate of diffusion of heat and mass has shown an increasing trend when thermal conductivity and mass diffusion coefficients are increased via rise in temperature of the fluid. The generative chemical reaction on the transport of specie relative to the impact on the transport of specie when it is compared with the impact of destructive chemical reaction on the transport of specie.
Genetic and functional insights into CDA-I prevalence and pathogenesis
Authors: Olijnik Aude-Anais , Roy Noémi B A , Scott Caroline , Marsh Joseph A , Brown Jill , Lauschke Karin , Ask Katrine , Roberts Nigel , Downes Damien J , Brolih Sanja , Johnson Errin , Xella Barbara , Proven Melanie , Hipkiss Ria , Ryan Kate , Frisk Per , Mäkk Johan , Stattin Eva-Lena Maria , Sadasivam Nandini , McIlwaine Louisa , Hill Quentin A , Renella Raffaele , Hughes Jim R , Gibbons Richard J , Groth Anja , McHugh Peter J , Higgs Douglas R , Buckle Veronica J , Babbs Christian 
Published: June 2020

BackgroundCongenital dyserythropoietic anaemia type I (CDA-I) is a hereditary anaemia caused by biallelic mutations in the widely expressed genes CDAN1 and C15orf41. Little is understood about either protein and it is unclear in which cellular pathways they participate.MethodsGenetic analysis of a cohort of patients with CDA-I identifies novel pathogenic variants in both known causative genes. We analyse the mutation distribution and the predicted structural positioning of amino acids affected in Codanin-1, the protein encoded by CDAN1. Using western blotting, immunoprecipitation and immunofluorescence, we determine the effect of particular mutations on both proteins and interrogate protein interaction, stability and subcellular localisation.ResultsWe identify six novel CDAN1 mutations and one novel mutation in C15orf41 and uncover evidence of further genetic heterogeneity in CDA-I. Additionally, population genetics suggests that CDA-I is more common than currently predicted. Mutations are enriched in six clusters in Codanin-1 and tend to affect buried residues. Many missense and in-frame mutations do not destabilise the entire protein. Rather C15orf41 relies on Codanin-1 for stability and both proteins, which are enriched in the nucleolus, interact to form an obligate complex in cells.ConclusionStability and interaction data suggest that C15orf41 may be the key determinant of CDA-I and offer insight into the mechanism underlying this disease. Both proteins share a common pathway likely to be present in a wide variety of cell types; however, nucleolar enrichment may provide a clue as to the erythroid specific nature of CDA-I. The surprisingly high predicted incidence of CDA-I suggests that better ascertainment would lead to improved patient care.
Holographic information theoretic quantities for Lifshitz black hole
Authors: Karar Sourav , Gangopadhyay Sunandan 
Published: June 2020

AbstractIn this paper, we have investigated the holographic entanglement entropy for a linear subsystem in a$$3+1$$3+1-dimensional Lifshitz black hole. The entanglement entropy has been analysed in both the infra-red and ultra-violet limits, and has also been computed in the near horizon approximation. The notion of a generalized temperature in terms of the renormalized entanglement entropy has been introduced. This also leads to a generalized thermodynamics like law$$E=\frac{1}{2}T_g S_{REE}$$E=12TgSREE. The generalized temperature has been defined in such a way that it reduces to the Hawking temperature in the infra-red limit. We find that the inverse of the generalized temperature ($$\beta _g=1/T_g$$βg=1/Tg) attains a non-zero value when the subsystem length becomes zero although it is zero in case of the Schwarzschild-AdS black hole. We have then computed the holographic subregion complexity. We find that the subregion complexity has logarithmic divergence which was absent in case of the$$3+1$$3+1-dimensional Schwarzschild-AdS black hole. Then the Fisher information metric and the fidelity susceptibility for the same linear subsystem have also been computed using the bulk dual prescriptions. It has been observed that the two metrics are not related to each other.
Chapter 11 Coal mining subsidence in the UK
Authors: Donnelly Laurance 
Published: June 2020

Abstract
One of the geohazards associated with coal mining is subsidence. Coal was originally extracted where it outcropped, then mining became progressively deeper via shallow workings including bell pits, which later developed into room-and-pillar workings. By the middle of the 1900s, coal was mined in larger open pits and underground by longwall mining methods. The mining of coal can often result in the subsidence of the ground surface. Generally, there are two main types of subsidence associated with coal mining. The first is the generation of crown holes caused by the collapse of mine entries and mine roadway intersections and the consolidation of shallow voids. The second is where longwall mining encourages the roof to fail to relieve the strains on the working face and this generates a subsidence trough. The ground movement migrates upwards and outwards from the seam being mined and ultimately causes the subsidence and deformation of the ground surface. Methods are available to predict mining subsidence so that existing or proposed structures and land developments may be safeguarded. Ground investigative methods and geotechnical engineering options are also available for sites that have been or may be adversely affected by coal mining subsidence.
Coronavirus Disease 2019 Catheterization Laboratory Survey
Authors: Banerjee Subhash , Tarantini Giuseppe , Abu‐Fadel Mazen , Banerjee Avantika , Little Bertis B. , Sorajja Paul , Shishehbor Mehdi H. , Brilakis Emmanouil S. 
Published: June 2020

Background
The coronavirus disease 2019 pandemic is expected to affect operations and lifestyles of interventional cardiologists around the world in unprecedented ways. Timely gathering of information on this topic can provide valuable insight and improve the handling of the ongoing and future pandemic outbreaks.

Methods and Results
A survey instrument developed by the authors was disseminated via e‐mail, text messaging, WhatsApp, and social media to interventional cardiologists between April 6, 2020, and April 11, 2020. A total of 509 responses were collected from 18 countries, mainly from the United States (51%) and Italy (36%). Operators reported significant decline in coronary, structural heart, and endovascular procedure volumes. Personal protective equipment was available to 95% of respondents; however FIT‐tested N95 or equivalent masks were available to only 70%, and 74% indicated absence of coronavirus disease 2019 pretesting. Most (83%) operators expressed concern when asked to perform cardiac catheterization on a suspected or confirmed coronavirus disease 2019 patient, primarily because of fear of viral transmission (88%). Although the survey demonstrated significant compliance with social distancing, high use of telemedicine (69%), and online education platforms (80%), there was concern over impending financial loss.

Conclusions
Our survey indicates significant reduction in invasive procedure volumes and concern for viral transmission. There is near universal adoption of personal protective equipment; however, coronavirus disease 2019 pretesting and access to FIT‐tested N95 masks is suboptimal. Although there is concern over impending financial loss, substantial engagement in telemedicine and online education is reported.
Guidance on Short‐Term Management of Atrial Fibrillation in Coronavirus Disease 2019
Authors: Rattanawong Pattara , Shen Win , El Masry Hicham , Sorajja Dan , Srivathsan Komandoor , Valverde Arturo , Scott Luis R. 
Published: June 2020

Abstract
Atrial fibrillation is a common clinical manifestation in hospitalized patients with coronavirus disease 2019 (COVID‐19). Medications used to treat atrial fibrillation, such as antiarrhythmic drugs and anticoagulants, may have significant drug interactions with emerging COVID‐19 treatments. Common unintended nontherapeutic target effects of COVID‐19 treatment include potassium channel blockade, cytochrome P 450 isoenzyme inhibition or activation, and P‐glycoprotein inhibition. Drug‐drug interactions with antiarrhythmic drugs and anticoagulants in these patients may lead to significant bradycardia, ventricular arrhythmias, or severe bleeding. It is important for clinicians to be aware of these interactions, drug metabolism changes, and clinical consequences when choosing antiarrhythmic drugs and anticoagulants for COVID‐19 patients with atrial fibrillation. The objective of this review is to provide a practical guide for clinicians who are managing COVID‐19 patients with concomitant atrial fibrillation.
Limitations of the Ordinary-Crimes Approach to the International Crime of Rape: the Case of Uganda
Authors: Lubaale Emma Charlene 
Published: June 2020

Abstract
Not many states have effective national laws on prosecution of international crimes. Presently, of the 124 states parties to the Rome Statute of the International Criminal Court (Rome Statute), less than half have specific national legislation incorporating international crimes. Some faith has been placed in the ordinary-crimes approach; the assumption being that states without effective laws on international crimes can prosecute on the basis of ordinary crimes. This article assesses the practicality of this approach with regard to the crime of rape in Uganda. Based on this assessment, the author draws a number of conclusions. First, that there are glaring gaps in the Ugandan definition of rape, making it impossible for it to be relied on. Secondly, although national courts have the option to interpret national laws with a view to aligning them with international law, the gaps salient in the definition of ordinary rape are too glaring; they cannot be remedied by way of interpretation without undermining the principle of legality. Thirdly, prosecuting the international crime of rape as an ordinary crime suggests that approaches applicable to the prosecution of ordinary rape will be invoked. Because these approaches were never intended to capture the reality of the international crime of rape, the ordinary-crimes approach remains illusory.
The Status in Nigeria of Treaties Predating the 1979 Constitution: Reflections on JFS v. Brawal Line Ltd
Authors: Enabulele Amos Osaigbovo , Osadolor Faith Osama 
Published: June 2020

Abstract
It is an essential ingredient of sovereignty that every State has an absolute jurisdiction to determine the laws that apply within its territory and to determine, by its laws, the organ of the State that has the competence to make laws and the procedures to be followed. The competent organ that makes municipal law (the legislature) is usually different from the organ that makes international law (the executive). As a result, and following the dictates of separation of powers, while the executive is competent to enter into treaties, its competence is eroded by the competence of the legislature when a treaty is intended to be applied to municipal subjects; such a treaty intrudes into the competence of the legislature. When this occurs, the municipal applicability of the treaty would turn on the requirements specified by municipal law. This is the function of section 12(1) of the 1999 Constitution (as amended). This section bars the executive from transforming its treaty-making power into legislative powers by requiring legislative approval for the application of a treaty in Nigeria. Expectedly, the section has been variously interpreted and applied by Nigerian courts. This paper examines the views expressed by the Supreme Court in JFS v. Brawal Line Ltd and argues that the Supreme Court failed to give proper expression to the dualist nature of that section.
The Right to Privacy v National Security in Africa: Towards a Legislative Framework Which Guarantees Proportionality in Communications Surveillance
Authors: Mavedzenge Justice Alfred 
Published: June 2020

Abstract
Governments often resort to communications surveillance in order to combat threats against national security. Communication surveillance infringes upon the right to privacy. In order to protect privacy, international law requires communication surveillance to be proportionate. However, very little has been written to justify why this right deserves such protection in Africa, given counter-arguments suggesting that where national security is threatened, the state must be permitted to do everything possible to avert the threat, and the protection of privacy is an inconvenience. This article addresses these counter-arguments by demonstrating that the right to privacy deserves protection because it is as important as defending national security. It analyses approaches taken by selected African countries to regulate authorisation of communication surveillance. This article questions the assumption that prior judicial authorisation is the ideal approach to regulating communication surveillance in order to guarantee proportionality, and it suggests a need to consider other alternatives.
Acute kidney injury, stroke and death after cardiopulmonary bypass surgery: the role of perfusion flow and pressure
Authors: Turner Laura , Hardikar Ashutosh , Jose Matthew D , Bhattarai Keshav , Fenton Carmel , Sharma Rajiv , Kirkland Geoff , Jeffs Lisa , Breslin Monique , Silva Ragaini Bruna , Newland Richard F 
Published: June 2020

Introduction: Acute kidney injury after cardiopulmonary bypass surgery is associated with morbidity and mortality. This study aims to evaluate the role of low perfusion flow and pressure in the development of cardiopulmonary bypass–associated acute kidney injury, stroke and death, using multicentre registry data. Methods: We identified patients from the Australian and New Zealand Collaborative Perfusion Registry who underwent coronary artery bypass grafting and/or valvular surgery between 2008 and 2018. Primary predictor variables were the length of time the perfusion flow was <1.6 L/min/m2 and the length of time perfusion pressure was < 50mmHg. The primary outcome was new postoperative acute kidney injury defined by the risk-injury-failure-loss-end stage criteria. Secondary outcomes were stroke and in-hospital death. The influence of perfusion flow and pressure during cardiopulmonary bypass on the primary and secondary outcomes was estimated using separate multivariate models. Results: A total of 16,356 patients were included. The mean age was 66 years and 75% were male. Acute kidney injury was observed in 1,844 patients (11%), stroke in 204 (1.3%) and in-hospital death in 286 (1.8%). Neither the duration of the time spent for perfusion flow (<1.6 L/minute/m2) nor the duration of the time spent for perfusion pressure (<50 mmHg) was associated with postoperative acute kidney injury, stroke or death in adjusted models. Conclusions: Neither low perfusion pressure nor low perfusion flow during cardiopulmonary bypass were predictive of postoperative acute kidney injury, stroke or death.
Influence of Glenoid Labral Bumper Height and Capsular Volume on Clinical Outcomes After Arthroscopic Bankart Repair as Assessed With Serial CT Arthrogram: Can Anterior-Inferior Volume Fraction Be a Prognostic Factor?
Authors: Lee Seung-Jun , Kim Jung-Han , Gwak Heui-Chul , Kim Chang-Wan , Lee Chang-Rack , Jung Soo-Hwan , Kwon Chung-Il 
Published: June 2020

Background: Arthroscopic labral repair combined with capsular plication decreases joint volume and restores glenoid labral bumper height; thus, the procedure helps decrease capsular redundancy. However, the decreased volume and restored glenoid labral bumper height could change over time, which could influence the outcome of the operation. Purpose: To (1) measure glenoid labral bumper height and capsular volume quantitatively in serial computed tomography arthrography (CTA) and evaluate the relationship between bumper height and joint volume and (2) compare the difference in bumper height and joint volume between groups with and without apprehension after arthroscopic Bankart repair. Study Design: Case-control study; Level of evidence, 3. Methods: Patients who had undergone arthroscopic Bankart repair between January 2012 and June 2016, and were assessed by CTA 3 to 6 months and 12 to 18 months after the operation were included. An image reconstruction program (3-dimensional slicer) was used to calculate inferior, anterior-inferior, and posterior-inferior joint volumes; the ratio of the anterior-inferior volume to the inferior volume was defined as the anterior-inferior volume fraction (VFAI). We also measured glenoid labral bumper height at the 5-, 4-, and 3-o’clock positions. Results: A total of 50 patients were enrolled as study participants (mean age, 25.2 ± 9.29 years). Of these, 10 patients had either redislocation or apprehension, and 40 patients had neither. A significant correlation was observed between 5-o’clock glenoid labral bumper height and VFAI on early CTA (3-6 months) and late CTA (12-18 months) (early CTA: Pearson coefficient, –0.335, P = .040; late CTA: Pearson coefficient, –0.468, P = .003). VFAI at the early CTA was 42.20 ± 10.15 in the group with apprehension and 33.49 ± 9.66 in the group without apprehension; a significant difference was observed. VFAI at the late CTA was 45.84 ± 11.97 in the group with apprehension and 37.65 ± 9.70 in the group without apprehension and thus showed a significant difference between the 2 groups. However, the 3-, 4-, and 5-o’clock glenoid labral bumper heights on early and late CTAs did not show a statistically significant difference between the 2 groups. Conclusion: Early postoperative VFAI is related to postoperative apprehension and redislocation and might be reduced by increasing the 5-o’clock glenoid labral bumper height.
Carotid Stent Restenosis and Thrombosis in Rabbits: The Effect of Antiplatelet Agents
Authors: Kadoglou Nikolaos P. E. , Stasinopoulou Marianna , Giannakopoulos Triantafyllos , Papapetrou Anastasios , Dimitriou Constantinos , Travlou Anthi , Merkouri Efrosyni , Kostomitsopoulos Nikolaos , Liapis Christos D. 
Published: June 2020

Background: The purpose of the study was the comparative assessment of ticagrelor and clopidogrel effects on carotid post-balloon injury (PBI) and on post carotid artery stenting (CAS) rate of in-stent restenosis (ISR) and in-stent thrombosis in atherosclerotic rabbits. Methods: Forty-eight New Zealand white rabbits on high-fat diet were randomized into 4 groups: A1: PBI and clopidogrel (30 mg/kg/d), A2: PBI and ticagrelor (21 mg/kg twice daily), B1: PBI, CAS, and clopidogrel (30 mg/kg/d), B2: PBI, CAS, and ticagrelor (21 mg/kg twice daily). All rabbits received orally aspirin (10 mg/kg/d) and interventions were performed in their right carotid arteries (RCAs). Optical coherence tomography (OCT) and carotid angiography were performed at end point, while platelet aggregation and lipid profile were measured. After euthanasia both carotids were obtained for histological examination. Results: In B1 group, 3 rabbits presented thrombotic total occlusion of the stents, while none such episode was observed in B2 group. The neointimal areas in RCAs, calculated by OCT, did not differ between A1 and A2 groups, and between B1 and B2 groups ( P > .05). From the histological findings, the intima/(media + intima) percentage (%) in RCAs of balloon-injured rabbits did not present any difference between groups ( P = .812). Similarly, the immunohistochemically determined accumulation of endothelial cells and macrophages on vascular walls was equivalent between groups ( P > .05). Conclusion: Following carotid balloon injury and stenting, clopidogrel and ticagrelor did not show any differential effects on the extent of neointimal formation and ISR in atherosclerotic rabbits receiving aspirin. Three thrombotic stent occlusions were noted in the clopidogrel treatment group, but this finding was not statistically significant.
Effectiveness of the transcutaneous tibial nerve stimulation and pelvic floor muscle training with biofeedback in women with multiple sclerosis for the management of overactive bladder
Authors: Polat Dunya Cansu , Tulek Zeliha , Kürtüncü Murat , Panicker Jalesh N , Eraksoy Mefkure 
Published: June 2020

Background: Overactive bladder (OAB) is common in patients with multiple sclerosis (MS) with a limited number of treatment options. Objective: To investigate the effect of transcutaneous tibial nerve stimulation (TTNS) and pelvic floor muscle training (PFMT) with biofeedback on OAB symptoms in female MS patients. Methods: This study was conducted at the outpatient MS clinic in Istanbul. At baseline bladder diary, post-voiding residue (PVR), OAB, and Qualiveen Scales (QoL: Quality of Life; Siup: Specific Impact of Urinary Problems on QoL) were assessed. Patients were allocated to receive TTNS or PFMT daily for 6 weeks and reevaluated using the same tests. Results: Fifty-five patients (TTNS = 28, PFMT = 27) were included. Compared with baseline, both TTNS and PFMT groups improved in terms of OAB ( p = 0.0001, p = 0.0001), Qualiveen-siup ( p = 0.0001, p = 0.0001), Qualiveen-QoL ( p = 0.002, p = 0.006), PVR ( p = 0.0001, p = 0.21), frequency ( p = 0.0001, p = 0.69), nocturia ( p = 0.0001, p = 0.19), urgency ( p = 0.0001, p = 0.0001), and urge incontinence ( p = 0.0001, p = 0.0001). Between-group comparisons showed significant differences in 24-hour frequency ( p = 0.002) in favor of TTNS. Conclusion: Our study demonstrates the efficacy of both TTNS and PFMT for managing OAB symptoms in MS, associated with a significant impact on QoL, but did not show superiority of the methods. Further studies are needed to explore differences between these two non-invasive treatments.