bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Through others we become ourselves”: The dialectics of predictive coding and active inference
Authors: Bolis Dimitris , Schilbach Leonhard 
Published: May 2020

Abstract
Thinking through other minds creatively situates the free-energy principle within real-life cultural processes, thereby enriching both sociocultural theories and Bayesian accounts of cognition. Here, shifting the attention from thinking-through to becoming-with, we suggest complementing such an account by focusing on the empirical, computational, and conceptual investigation of the multiscale dynamics of social interaction.
TTOM in action: Refining the variational approach to cognition and culture
Authors: Veissière Samuel P. L. , Constant Axel , Ramstead Maxwell J. D. , Friston Karl J. , Kirmayer Laurence J. 
Published: May 2020

AbstractThe target article “Thinking Through Other Minds” (TTOM) offered an account of the distinctively human capacity to acquire cultural knowledge, norms, and practices. To this end, we leveraged recent ideas from theoretical neurobiology to understand the human mind in social and cultural contexts. Our aim was bothsynthetic– building an integrative model adequate to account for key features of cultural learning and adaptation; andprescriptive– showing how the tools developed to explain brain dynamics can be applied to the emergence of social and cultural ecologies of mind. In this reply to commentators, we address key issues, including: (1) refining the concept of culture to show how TTOM and the free-energy principle (FEP) can capture essential elements of human adaptation and functioning; (2) addressing cognition as an embodied, enactive, affective process involving cultural affordances; (3) clarifying the significance of the FEP formalism related to entropy minimization, Bayesian inference, Markov blankets, and enactivist views; (4) developing empirical tests and applications of the TTOM model; (5) incorporating cultural diversity and context at the level of intra-cultural variation, individual differences, and the transition to digital niches; and (6) considering some implications for psychiatry. The commentators’ critiques and suggestions point to useful refinements and applications of the model. In ongoing collaborations, we are exploring how to augment the theory with affective valence, take into account individual differences and historicity, and apply the model to specific domains including epistemic bias.
Optimal Trajectory Generation for a 6-DOF Parallel Manipulator Using Grey Wolf Optimization Algorithm
Authors: Choubey Chandan , Ohri Jyoti 
Published: May 2020

SUMMARYIn this paper we designed an optimal trajectory generation (OTG) method to generate easy and errorless continuous path motion with quick converging using Grey Wolf Optimization (GWO) method. The proposed OTG method finds the trajectory path with minimum tracking error, combined speed, joint increasing speed wrinkle, as well as joint lurching move to follow an error-free smooth continuous path.
The effects of phonological neighborhood density in childhood word production and recognition in Russian are opposite to English
Authors: ARUTIUNIAN Vardan , LOPUKHINA Anastasiya 
Published: May 2020

AbstractThis study investigates howphonological neighborhood density(PND) affects word production and recognition in 4-to-6-year-old Russian children in comparison to adults. Previous experiments with English-speaking adults showed that a dense neighborhood facilitated word production but inhibited recognition whereas a sparse neighborhood inhibited production but facilitated recognition. Importantly, these effects are not universal because a reverse PND pattern was found in Spanish-speaking adults. Probably, PND effects depend on the morphological properties of language.This study focuses on PND effects in word production and recognition in terms of facilitation and inhibition in Russian. Our results are consistent with those in Spanish: Russian-speaking adults produced words with dense neighborhoods more slowly and recognized them faster than words with sparse neighborhoods. Russian children showed the same PND effect in recognition and no effect was found in production. The findings support the hypothesis that PND effects in word production and recognition are influenced by the morphological system of language.
The role of socioeconomic and sociocultural predictors of Spanish and English proficiencies of young Latino children of immigrants
Authors: COLLINS Brian A. , TOPPELBERG Claudio O. 
Published: May 2020

AbstractYoung Latino children of immigrants typically speak primarily Spanish at home and are exposed to varying amounts of English. As a result, they often enter school with a wide range of proficiencies in each language. The current study investigated family background, language use at home and early childhood settings as predictors of Spanish and English language proficiencies among Latino dual language children (N = 228). Findings demonstrated divergent sets of predictors were associated with either Spanish or English proficiencies at kindergarten and second grade. Sociocultural variables (parent origin, gender, home language use, home literacy practices, and language use in early childhood settings) predicted children's Spanish proficiency, while socioeconomic variables (poverty, and maternal and paternal education) predicted children's English proficiency, with little to no overlap in these predictions. These results suggest that different supports are required for proficiency in Spanish and in English, highlighting the importance of sociocultural and socioeconomic factors.
Children’s psychosocial factors of healthy meal preparation as predictors for nutritional status measures
Authors: Ng Choon Ming , Satvinder Kaur , Koo Hui Chin , Yap Roseline Wai Kuan , Mukhtar Firdaus 
Published: May 2020

Abstract. Involving school-age children in the preparation of healthy meals is shown to be associated with positive eating behavior. Yet, it remains unclear whether this can extend to their nutritional status. The present study aimed to determine the association of school-age children’s psychosocial factors (knowledge, attitude, practice, self-efficacy) towards healthy meal preparation with their nutritional status (BMI-for-age, waist circumference, body fat percentage). Stratified random sampling was used to select primary schools (n = 8) in Kuala Lumpur, Malaysia. Two hundred school children aged between 9–11 years old were involved. Psychosocial factors towards healthy meal preparation were assessed using validated questionnaire. Anthropometry measures were determined using standard protocol. Almost half (46 %) of the school-age children were obese/overweight, 39 % were abdominally obese and 40 % were overfat. Approximately half had poor knowledge (49 %), poor practice (45 %), good attitude (56 %) and good self-efficacy (47 %) towards healthy meal preparation. Significant positive correlations were observed between knowledge with attitude (r = 0.23, p < 0.001); knowledge with self-efficacy (r = 0.30, p < 0.001); attitude with practice (r = 0.34, p < 0.001); attitude with self-efficacy (r = 0.59, p < 0.001) and practice with self-efficacy (r = 0.50, p < 0.001). Adjusted logistic regression revealed that school-age children with good attitude were less likely to be abdominally obese (OR = 0.87, 95 % Cl = 0.78 to 0.96) and overfat (OR = 0.84, 95 % Cl = 0.76 to 0.94). Children with good knowledge had lower risk of being abdominally obese (OR = 0.84, 95 % Cl = 0.72 to 0.97). Findings revealed that children’s psychosocial factors were interrelated, and improvements may have the potential in affecting nutritional status. Hands-on healthy meal preparation should be explored further as an innovative approach to address the obesity epidemic.
Seasonal Variation of the Deep Limb of the Pacific Meridional Overturning Circulation at Yap‐Mariana Junction
Authors: Wang Jianing , Ma Qiang , Wang Fan , Lu Youyu , Pratt Larry J. 
Published: May 2020

AbstractThis study reveals the seasonal variability of the lower and upper deep branches of the Pacific Meridional Overturning Circulation (L‐PMOC and U‐PMOC) in the Yap‐Mariana Junction (YMJ) channel, a major gateway for deep flow into the western Pacific. On the western side of the YMJ channel, mooring observations in 2017 and in 1997 show the seasonal phase of the L‐PMOC at depths of 3,800–4,400 m: strong northward flow with speed exceeding 20 cm s−1 and lasting from December to next May and weak flow during the following 6 months. On the eastern side of the channel, mooring observations during 2014–2017 show two southward deep flows with broadly seasonal phases, one being the return flow of L‐PMOC below ~4,000 m and with the same phase of L‐PMOC but reduced magnitude. The second, shallower, southward deep flow corresponds to the U‐PMOC observed within 3,000–3,800 m and with opposite phase of L‐PMOC, that is, strong (weak) southward flow appearing during June–November (December–May). Seasonal variations of the L‐PMOC and U‐PMOC are accompanied by the seasonal intrusions of the Lower and Upper Circumpolar Waters (LCPW and UCPW) in lower and upper deep layers, which change the isopycnal structure and the deep currents in a way consistent with geostrophic balance.
The Atmospheric Boundary Layer and the “Gray Zone” of Turbulence: A Critical Review
Authors: Honnert Rachel , Efstathiou Georgios A. , Beare Robert J. , Ito Junshi , Lock Adrian , Neggers Roel , Plant Robert S. , Shin Hyeyum Hailey , Tomassini Lorenzo , Zhou Bowen 
Published: May 2020

AbstractRecent increases in computing power mean that atmospheric models for numerical weather prediction are now able to operate at grid spacings of the order of a few hundred meters, comparable to the dominant turbulence length scales in the atmospheric boundary layer. As a result, models are starting to partially resolve the coherent overturning structures in the boundary layer. In this resolution regime, the so‐called boundary layer “gray zone,” neither the techniques of high‐resolution atmospheric modeling (a few tens of meters resolution) nor those of traditional meteorological models (a few kilometers resolution) are appropriate because fundamental assumptions behind the parameterizations are violated. Nonetheless, model simulations in this regime may remain highly useful. In this paper, a newly formed gray zone boundary layer community lays the basis for parameterizing gray zone turbulence, identifies the challenges in high‐resolution atmospheric modeling and presents different gray zone boundary layer models. We discuss both the successful applications and the limitations of current parameterization approaches, and consider various issues in extending promising research approaches into use for numerical weather prediction. The ultimate goal of the research is the development of unified boundary layer parameterizations valid across all scales.
Constraints on the Mineralogy and Geochemistry of Vera Rubin Ridge, Gale Crater, Mars, From Mars Science Laboratory Sample Analysis at Mars Evolved Gas Analyses
Authors: McAdam Amy C. , Sutter Brad , Archer P. Douglas , Franz Heather B. , Wong Gregory M. , Lewis James M. T. , Eigenbrode Jennifer L. , Stern Jennifer C. , Knudson Christine A. , Clark Joanna V. , Andrejkovičová Slavka , Ming Douglas W. , Morris Richard V. , Achilles Cherie N. , Rampe Elizabeth B. , Bristow Thomas F. , Navarro‐González Rafael , Mahaffy Paul R. , Thompson Lucy M. , Gellert Ralf , Williams Amy J. , House Christopher H. , Johnson Sarah S. 
Published: May 2020

AbstractVera Rubin ridge (VRR) is a topographic high within the layers of Mount Sharp, Gale crater, that exhibits a strong hematite spectral signature from orbit. The Mars Science Laboratory Curiosity rover carried out a comprehensive investigation to understand the depositional and diagenetic processes recorded in the rocks of VRR. Sample Analysis at Mars (SAM) evolved gas analyses (EGA) were performed on three samples from the ridge and one from directly beneath the ridge. SAM evolved H2O data suggested the presence of an Fe‐rich dioctahedral smectite, such as nontronite, in the sample from beneath the ridge. H2O data are also consistent with ferripyrophyllite in VRR samples. SAM SO2 data indicated that all samples contained Mg sulfates and some Fe sulfate. Several volatile detections suggested trace reduced sulfur sources, such as Fe sulfides and/or S‐bearing organic compounds, in two samples while significant O2 and NO evolved from one sample indicated the presence of oxychlorine and nitrate/nitrite salts, respectively. The O2 evolution was the second highest to date and the first observed in ~1,200 sols. HCl released from all samples likely resulted, in part, from trace chloride salts. All samples evolved CO2 and CO consistent with oxidized carbon compounds (e.g., oxalates), while some CO2 may result from carbonate. SAM‐derived constraints on the mineralogy and chemistry of VRR materials, in the context of additional mineralogy, geochemistry, and sedimentology information obtained by Curiosity, support a complex diagenetic history that involved fluids of a range of possible salinities, redox characteristics, pHs, and temperatures.
Illumination of Damage in Intact Rocks by Ultrasonic Transmission‐Reflection and Digital Image Correlation
Authors: Shirole Deepanshu , Hedayat Ahmadreza , Walton Gabriel 
Published: May 2020

AbstractLaboratory‐scale experiments on intact rocks are critical to the development of physics‐based fundamental understanding of various geophysical phenomena. In this work, the capability of ultrasonic wave transmission (T‐mode) and reflection (R‐mode) to monitor damage progression in uniaxially loaded prismatic intact rock specimens has been analyzed, as it is imperative to study the observations and document the capabilities of these techniques in a controlled environment. This study is novel in the sense that the R‐mode linear ultrasonic testing (LUT) has been rarely employed in studying intact rock damage processes in a laboratory setting, with most of the studies utilizing a direct transmission (T‐mode) approach or focusing on macroscopically fractured material. The two‐dimensional digital image correlation (2‐D DIC) full‐field strain measurement approach was also used in‐sync with the LUT monitoring to explicitly correlate the stress‐induced damage in the specimens with the changes observed in the ultrasonic (T‐mode and R‐mode) signals. The results show that both the T‐mode and R‐mode LUT approaches are sensitive to detect the evolution of tensile and shear damage in the specimens, with the R‐mode ultrasonic signals showing higher degree of sensitivity to the damage in the rocks, immediately following the initiation of damage in the rock volume.
Differential Responses of Maximum Versus Median Chlorophyll‐a to Air Temperature and Nutrient Loads in an Oligotrophic Lake Over 31 Years
Authors: Ward Nicole K. , Steele Bethel G. , Weathers Kathleen C. , Cottingham Kathryn L. , Ewing Holly A. , Hanson Paul C. , Carey Cayelan C. 
Published: May 2020

AbstractGlobally, phytoplankton abundance is increasing in lakes as a result of climate change and land‐use change. The relative importance of climate and land‐use drivers has been examined primarily for mesotrophic and eutrophic lakes. However, oligotrophic lakes show different sensitivity to climate and land‐use drivers than mesotrophic and eutrophic lakes, necessitating further exploration of the relative contribution of the two drivers of change to increased phytoplankton abundance. Here, we investigated how air temperature (a driver related to climate change) and nutrient load (a driver related to land‐use and climate change) interact to alter water quality in oligotrophic Lake Sunapee, New Hampshire, USA. We used long‐term data and the one‐dimensional hydrodynamic General Lake Model (GLM) coupled with Aquatic EcoDyanmics (AED) modules to simulate water quality. Over the 31‐year simulation, summer median chlorophyll‐a concentration was positively associated with summer air temperature, whereas annual maximum chlorophyll‐a concentration was positively associated with the previous 3 years of external phosphorus load. Scenario testing demonstrated a 2°C increase in air temperature significantly increased summer median chlorophyll‐a concentration, but not annual maximum chlorophyll‐a concentration. For both maximum and median chlorophyll‐a concentration, doubling external nutrient loads of total nitrogen and total phosphorus at the same time, or doubling phosphorus alone, resulted in a significant increase. This study highlights the importance of aligning lake measurements with the ecosystem metrics of interest, as maximum chlorophyll‐a concentration may be more uniquely sensitive to nutrient load and that typical summer chlorophyll‐a concentration may increase due to warming alone.
Endothelial-to-mesenchymal transition in anticancer therapy and normal tissue damage
Authors: Choi Kyu Jin , Nam Jae-Kyung , Kim Ji-Hee , Choi Seo-Hyun , Lee Yoon-Jin 
Published: May 2020

AbstractEndothelial-to-mesenchymal transition (EndMT) involves the phenotypic conversion of endothelial-to-mesenchymal cells, and was first discovered in association with embryonic heart development. EndMT can regulate various processes, such as tissue fibrosis and cancer. Recent findings have shown that EndMT is related to resistance to cancer therapy, such as chemotherapy, antiangiogenic therapy, and radiation therapy. Based on the known effects of EndMT on the cardiac toxicity of anticancer therapy and tissue damage of radiation therapy, we propose that EndMT can be targeted as a strategy for overcoming tumor resistance while reducing complications, such as tissue damage. In this review, we discuss EndMT and its roles in damaging cardiac and lung tissues, as well as EndMT-related effects on tumor vasculature and resistance in anticancer therapy. Modulating EndMT in radioresistant tumors and radiation-induced tissue fibrosis can especially increase the efficacy of radiation therapy. In addition, we review the role of hypoxia and reactive oxygen species as the main stimulating factors of tissue damage due to vascular damage and EndMT. We consider drugs that may be clinically useful for regulating EndMT in various diseases. Finally, we argue the importance of EndMT as a therapeutic target in anticancer therapy for reducing tissue damage.
A pre-specified model based on four kallikrein markers in blood improves predictions of adverse pathology and biochemical recurrence after radical prostatectomy
Authors: Haese Alexander , Tin Amy L. , Carlsson Sigrid V. , Sjoberg Daniel D. , Pehrke Dirk , Steuber Thomas , Huland Hartwig , Graefen Markus , Scardino Peter T. , Schlomm Thorsten , Vickers Andrew J. , Lilja Hans , Sauter Guido 
Published: May 2020

Abstract
Background
A pre-specified model based on four kallikrein markers in blood, commercially available as 4Kscore, predicts Gleason Grade (GG) 3 + 4 or higher prostate cancer on biopsy. However, sampling error and variation in pathology reporting may miss aggressive disease.

Methods
The 4Kscore was measured in cryopreserved blood from 2330 men obtained before prostatectomy at a single institution between 2002 and 2010. Adverse surgical pathology and biochemical recurrence (BCR) were pre-specified to be assessed in all men, biopsy GG 3 + 3, and 3 + 4.

Results
Adjusted for established clinical predictors, the 4Kscore was significantly associated with adverse pathology (OR 1.49; 95% CI 1.32, 1.67; p < 0.0001). Adding 4Kscore increased discrimination from (AUC) 0.672 to 0.718 and 0.644 to 0.659 within biopsy GG 3 + 3 and 3 + 4, respectively. Higher 4Kscore was associated with higher risk of BCR (HR 1.16, 95% CI 1.06, 1.26; p = 0.001). Adding 4Kscore improved the prediction of BCR (C-index 0.630–0.660) within GG 3 + 3, but not GG 3 + 4.

Conclusions
The 4Kscore can help guide the clinical decision whether additional risk assessment—such as confirmatory biopsy—is needed to decide between active surveillance versus curative therapy. Evidence that the panel could influence management in biopsy GG 3 + 4 is less strong and requires further investigation.
Molecular mechanisms of methylglyoxal-induced aortic endothelial dysfunction in human vascular endothelial cells
Authors: Lee Jae Hyuk , Parveen Amna , Do Moon Ho , Kang Min Cheol , Yumnam Silvia , Kim Sun Yeou 
Published: May 2020

AbstractMethylglyoxal (MGO)-induced cellular apoptosis, oxidative stress, inflammation, and AGE formation are specific events that induce vascular endothelial cell (EC) toxicity in endothelial dysfunction (ED). MGO accumulates quickly in various tissues and plays a prominent role in the pathogeneses of several diabetic complications. Unbalanced angiogenesis is a gateway to the development of diabetic complications. EC apoptosis and autophagy work together to regulate angiogenesis by interacting with different angiogenic factors. In addition to understanding the deep mechanism regarding MGO-dependent autophagy/apoptosis may provide new therapeutic applications to treat diabetes and diabetic complications. Therefore, the present study aimed to investigate the regulatory effects of MGO-induced autophagy and apoptosis on angiogenesis in HAoEC and to elucidate the molecular mechanisms to discover new target base therapy for diabetes and diabetic complications. In MGO-stimulated HAoEC, protein expression was identified using a western blot, autophagosomes were observed by bio-transmission electron microscopy (TEM), and cell autophagic vacuoles and flux were measured using a confocal microscope. We found that MGO significantly induced autophagy, declined the pro-angiogenic effect, decreased proliferation, migration, and formation of tube-like structures, and increased autophagic vacuoles, flux and autophagosomes in the HAoEC in a dose-dependent manner. We observed that MGO-induced autophagic cell death and inhibited the ROS-mediated Akt/mTOR signaling pathway. MGO also triggered apoptosis by elevating the cleaved caspase-3 to Bax/Bcl-2 ratio and through activation of the ROS-mediated MAPKs (p-JNK, p-p38, and p-ERK) signaling pathway. Collectively, these findings suggest that autophagy and apoptosis inhibit angiogenesis via the ROS-mediated Akt/mTOR and MAPKs signaling pathways, respectively, when HAoEC are treated with MGO.
Electrically tunable photonic band gap structure in monodomain blue-phase liquid crystals
Authors: Manda Ramesh , Pagidi Srinivas , Heo Yunjin , Lim Young Jin , Kim MinSu , Lee Seung Hee 
Published: May 2020

AbstractPhotonic band gap materials have the ability to modulate light. When they can be dynamically controlled beyond static modulation, their versatility improves and they become very useful in scientific and industrial applications. The quality of photonic band gap materials depends on the tunable wavelength range, dynamic controllability, and wavelength selectivity in response to external cues. In this paper, we demonstrate an electrically tunable photonic band gap material that covers a wide range (241 nm) in the visible spectrum and is based on a monodomain blue-phase liquid crystal stabilized by nonmesogenic and chiral mesogenic monomers. With this approach, we can accurately tune a reflection wavelength that possesses a narrow bandwidth (27 nm) even under a high electric field. The switching is fully reversible owing to a relatively small hysteresis with a fast response time, and it also shows a wider viewing angle than that of cholesteric liquid crystals. We believe that the proposed material has the potential to tune color filters and bandpass filters.