bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of anxiety and depression among newly diagnosed people living with HIV: A longitudinal study
Authors: Garrido‐Hernansaiz Helena , Alonso‐Tapia Jesús 
Published: January 2020

This longitudinal study examined whether past resilience and internalized stigma predicted anxiety and depression among newly diagnosed Spanish‐speaking people living with HIV (PLWH). We also analyzed whether coping strategies mediated this relationship. Data were collected at two time points from 119 PLWH. Approximately a third of participants had scores indicative of anxiety symptoms, the same result was found for depressive symptoms. Structural equations modeling revealed that 61% of the variance of anxiety and 48% of the variance of depression 8 months after diagnosis was explained by the proposed model, which yielded a good fit to data. Anxiety and depressive symptoms were significantly and negatively predicted by positive thinking, thinking avoidance, and past resilience, and positively predicted by self‐blame. Additionally, anxiety was positively predicted by internalized stigma. Past resilience negatively predicted internalized stigma, self‐blame, and thinking avoidance and it positively predicted positive thinking. Internalized stigma positively predicted self‐blame. Moreover, internalized stigma had a significant indirect effect on anxiety symptoms through self‐blame, and past resilience had significant indirect effects on anxiety symptoms and depressive symptoms through internalized stigma and coping. The results point to the need for clinicians and policy makers to conduct systematic assessments and implement interventions to reduce internalized stigma and train people living with HIV to identify and use certain coping behaviors.
Measures of Similarity
Authors: Enflo Karin 
Published: January 2020

AbstractThis article analyses the relationship between the concept of single aspect similarity and proposed measures of similarity. More precisely, it compares eleven measures of similarity in terms of how well they satisfy a list of desiderata, chosen to capture common intuitions concerning the properties of similarity and the relations between similarity and dissimilarity. Three types of measures are discussed: similarity as commonality, similarity as a function of dissimilarity, and similarity as a joint function of commonality and difference. Relative to the desiderata, it is found that a measure of the second type fares the best. However, rather than recommend this measure alone as a measure of similarity, it is suggested that there are at least three separate concepts of single aspect similarity, corresponding to the three types of measures. In light of this proposal, three of the eleven measures (and variants of these) are deemed acceptable.
Evaluation of an electronic, patient‐focused management system aimed at preventing cytomegalovirus disease following solid organ transplantation
Authors: Ekenberg Christina , da Cunha‐Bang Caspar , Lodding Isabelle P. , Sørensen Søren S. , Sengeløv Henrik , Perch Michael , Rasmussen Allan , Gustafsson Finn , Wareham Neval E. , Kirkby Nikolai , Kjær Jesper , Helleberg Marie , Reekie Joanne , Lundgren Jens D. 
Published: January 2020

AbstractBackgroundCytomegalovirus (CMV) infection is common among solid organ transplant (SOT) recipients and may cause CMV disease. To optimize the implementation of existing prevention strategies, the Management of Post‐transplant Infections in Collaborating Hospitals (MATCH) program was developed. Two key performances of MATCH (diagnosing CMV infection at low viral load (VL) and before the onset of CMV disease) were assessed prior to, during and after the implementation of MATCH.MethodsThe MATCH program included a personalized surveillance plan, prophylaxis and preemptive therapy determined by the recipient's risk of CMV infection. The plan was composed through predefined algorithms and implemented through harvesting of real‐time data from medical records. Risk of CMV disease was compared for recipients transplanted during and after vs prior to the implementation of MATCH. Lung and non‐lung transplants were analyzed separately.ResultsA total of 593, 349, 520, and 360 SOT recipients were transplanted before (2007‐2010), during (2011‐2012), early after (2013‐2015), and late after (2016‐2017) implementation of MATCH with an observed reduction of diagnostic VL (P < .001) over time. Risk of CMV disease was reduced among non‐lung transplant recipients transplanted during (adjusted hazard ratios [95% CI] 0.15 [0.04‐0.54], P = .003), early after (aHR 0.27 [0.11‐0.63], P = .003), and late after (aHR 0.17 [0.06‐0.52], P = .002) compared with prior to MATCH. No significant change was observed among lung transplants.ConclusionImplementation of CMV preventive strategies through MATCH was associated with a reduced risk of CMV disease among non‐lung transplant recipients. Furthermore, the limitations of VL as a sole indicator for CMV disease in lung transplants were emphasized.
needs+PAST PARTICIPLE in regional Englishes on Twitter
Authors: Strelluf Christopher 
Published: January 2020

AbstractThe use of needs with a past participle (as in ‘The car needs washed’) has been identified as a feature of the US Midland, and of Englishes in Scotland, Northern Ireland, and northern England. However, linguists have generally not been able to study needs+PAST in natural language data. This study reports from a large corpus of needs+PAST productions built from tweets in 20 US cities, 17 UK cities, and 13 other cities. It confirms needs+PAST as a productive feature of Scotland, Belfast, Newcastle, and the US Midland, and supports claims that the construction spread via immigration. In doing so, it validates studies based on elicitations of grammaticality judgments, while also demonstrating new techniques to study low‐frequency linguistic variables. It provides quantitative evidence of the extent to which a settler variety of English may leave an imprint of itself over several centuries, and of the durability of regional dialect boundaries.
A Visual Sensitivity Analysis for Parameter-Augmented Ensembles of Curves
Authors: Ribés Alejandro , Pouderoux Joachim , Iooss Bertrand 
Published: January 2020

AbstractEngineers and computational scientists often study the behavior of their simulations by repeated solutions with variations in their parameters, which can be, for instance, boundary values or initial conditions. Through such simulation ensembles, uncertainty in a solution is studied as a function of various input parameters. Solutions of numerical simulations are often temporal functions, spatial maps, or spatio-temporal outputs. The usual way to deal with such complex outputs is to limit the analysis to several probes in the temporal/spatial domain. This leads to smaller and more tractable ensembles of functional outputs (curves) with their associated input parameters: augmented ensembles of curves. This article describes a system for the interactive exploration and analysis of such augmented ensembles. Descriptive statistics on the functional outputs are performed by principal component analysis (PCA) projection, kernel density estimation, and the computation of high density regions. This makes possible the calculation of functional quantiles and outliers. Brushing and linking the elements of the system allows in-depth analysis of the ensemble. The system allows for functional descriptive statistics, cluster detection, and finally, for the realization of a visual sensitivity analysis via cobweb plots. We present two synthetic examples and then validate our approach in an industrial use-case concerning a marine current study using a hydraulic solver.
Effects of Transpiration on the Unsteady Separated Stagnation-Point Flow and Heat Transfer Over a Moving Porous Plate
Authors: Dholey S. 
Published: January 2020

Abstract
The combined influence of normal transpiration and tangential movement of a porous surface on the unsteady separated stagnation-point flow and heat transfer of a viscous fluid is studied. This study is based on five physical parameters, namely (i) flow strength parameter a, (ii) suction/injection parameter d, (iii) plate velocity parameter λ, (iv) unsteadiness parameter β, and (v) Prandtl number Pr. This analysis shows an interesting relation β = 2a which allows us to derive some closed-form analytic solutions depending upon the unlikely values of d. For suction d &gt; 0, two attached flow solutions (AFS) without point of inflection are found in the range (−ad2/4−3&lt;λ&lt;−3), whereas for λ &gt; −3 only one solution of the same type is found for any given value of d. Besides them, the numerical computations reveal two types of AFS—one without and the other with a point of inflection in the range (−1.24658 ≤λ≤ −1.07) when d = β = 0. The present analysis confirms the nonexistence of the second attached flow solution after a certain value of suction d depending upon the choice of the values of λ in this range. A reverse flow solution (RFS) along with the above two solutions is found for a negative value of β which continues even for large rate of suction d. The asymptotic solutions of this flow problem have also been derived for large values of d which provide with the exact results after a certain value of d depending upon the values of the other parameters.
The role of Contrast-Enhanced Ultrasound for evaluating renal perfusion dynamics in partially reversible acute cortical kidney ischemia in a patient with sepsis
Authors: Giurgiu Alina Bianca , Kacso Ina Maria , Ionescu Daniela , Badea Radu 
Published: January 2020

We report the case of a sepsis-induced acute kidney injury accompanied by disseminated intravascular coagulation and thrombotic microangiopathy, responsible for subsequent renal microvascular thrombosis. Contrast-enhanced ultrasound was used to assess the thrombotic cortical kidney ischemia and its evolution over time.
Individual Response to External Training Load in Elite Football Players
Authors: Wiig Håvard , Andersen Thor Einar , Luteberget Live S. , Spencer Matt 
Published: January 2020

Purpose: To investigate within-player effect, between-player effect, and individual response of external training load from player tracking devices on session rating of perceived exertion training load (sRPE-TL) in elite football players. Methods: The authors collected sRPE-TL from 18 outfield players in 21 training sessions. Total distance, high-speed running distance (>14.4 m/s), very high-speed running distance (>19.8 m/s), PlayerLoad™, PlayerLoad2D™, and high-intensity events (HIE > 1.5, HIE > 2.5, and HIE > 3.5 m/s) were extracted from the tracking devices. The authors modeled within-player and between-player effects of single external load variables on sRPE-TL, and multiple levels of variability, using a linear mixed model. The effect of 2 SDs of external load on sRPE-TL was evaluated with magnitude-based inferences. Results: Total distance, PlayerLoad™, PlayerLoad2D™, and HIE > 1.5 had most likely substantial within-player effects on sRPE-TL (100%–106%, very large effect sizes). Moreover, the authors observed likely substantial between-player effects (12%–19%, small to moderate effect sizes) from the majority of the external load variables and likely to very likely substantial individual responses of PlayerLoad™, high-speed running distance, very high-speed running distance, and HIE > 1.5 (19%–30% coefficient of variation, moderate to large effect sizes). Finally, sRPE-TL showed large to very large between-session variability with all external load variables. Conclusions: External load variables with low intensity-thresholds had the strongest relationship with sRPE-TL. Furthermore, the between-player effect of external load and the individual response to external load advocate for monitoring sRPE-TL in addition to external load. Finally, the large between-session variability in sRPE-TL demonstrates that substantial amounts of sRPE-TL in training sessions are not explained by single external load variables.
Mechanical Properties of Treadmill Surfaces and Their Effects on Endurance Running
Authors: Colino Enrique , Garcia-Unanue Jorge , Gallardo Leonor , Foster Carl , Lucia Alejandro , Felipe Jose Luis 
Published: January 2020

Purpose:To characterize, for the first time, the mechanical properties of treadmill surfaces along with a practical interpretation of their influence on physiological and perceived demands during endurance running compared with other widely used surfaces such as asphalt and tartan tracks.Methods:Ten experienced male endurance runners performed a 40-minute running bout at a preferred constant speed on 3 different surfaces (after a randomized, counterbalanced order with a 7-d interval between trials): asphalt, tartan, or treadmill. Shock absorption, vertical deformation, and energy restitution were measured for the 3 surfaces. Intensity (based on heart rate data) and rating of perceived exertion were monitored.Results:The values of shock absorption averaged 0.0% (asphalt), 37.4% (tartan), and 71.3% (treadmill), while those of vertical deformation and energy restitution averaged 0.3, 2.2, and 6.5 mm and 90.8%, 62.6%, and 37.0%, respectively. Running intensity (as determined by heart rate data) was higher overall on the treadmill than tartan but not asphalt running. Except for the first 10 minutes, all mean rating of perceived exertion values were significantly higher in asphalt and treadmill than in tartan. No significant differences were identified between treadmill and asphalt.Conclusions:The considerably higher shock absorption of the treadmill than the tartan surface leads to a reduction in the amount of energy returned to the athlete, which in turn increases physiological stress and rating of perceived exertion during endurance running.
Indo-Burma passive amalgamation along the Kaladan Fault: Insights from zircon provenance in the Chittagong-Tripura Fold Belt (Bangladesh)
Authors: Yang Lei , Xiao Wenjiao , Jalalur Rahman M. Julleh , Windley Brian F. , Schulmann Karel , Ao Songjian , Zhang Ji’en , Chen Zhenyu , Hossain Md. Sakawat , Dong Yunpeng 
Published: January 2020

AbstractA clear insight of the Indo-Burma amalgamation is required for an understanding of the complex processes of the Indo-Asian collision. Where and when the northeastern part of the Indian subcontinent amalgamated with the Burma plate has not yet been well defined. In order to better understand the tectonic affiliations and evolution of the Indo-Burma Ranges (IBR), we report new detrital zircon U-Pb and Hf isotope data of nine sandstone/siltstone samples (late Miocene–Pliocene) from the Chittagong-Tripura Fold Belt, Bangladesh, which is in the Neogene belt of the IBR. Our results show that the zircon ages of all nine samples have three peaks at &lt;200 Ma, ca. 500 Ma, and 800–1000 Ma. The percentage of young (&lt;200 Ma) zircons increase from the Boka Bil Formation (6.9% to 15.2%) to the Tipam Formation (20.3% to 27.6%). The εHf(t) of most young zircons from the Boka Bil Formation suggest derivation from the Gangdese arc, whereas those from the Tipam Formation show an affinity with the Burma magmatic arc. Therefore, we suggest that the increase of young zircons in the Tipam Formation came from the Burma plate. Comparing provenances of the Paleogene and Neogene belts of the IBR, we suggest that they belong to the Burma plate and Indian subcontinent, respectively, and that the Kaladan Fault, separating these two belts, is the suture between the Indian and Burma terranes. The time of amalgamation is constrained by the ca. 2.5–3.9 Ma boundary between the Boka Bil and Tipam formations, and the eastern Indian promontory likely collided with the Burma plate ca. 11–12 Ma.
Comparison of carotid atherosclerotic plaques between subjects in Northern and Southern China: a Chinese atherosclerosis risk evaluation study
Authors: Yang Dandan , Ji Yang , Wang Dan , Watase Hiroko , Hippe Daniel S , Zhao Xihai , Yuan Chun 
Published: January 2020

Background and purpose
To investigate differences in the characteristics of carotid atherosclerotic plaques of symptomatic subjects in northern and southern China using MRI.

Methods

Sixty-three subjects in northern China (mean age: 59.1±8.6 years, 45 men) and 56 subjects in southern China (mean age: 60.4±8.6 years, 38 men) were included. All subjects underwent carotid artery multicontrast vessel wall MRI. Plaque morphology, calciﬁcation, lipid-rich necrotic core, intraplaque haemorrhage, luminal surface disruption and high-risk plaque were measured and identified. All plaque characteristics were compared between subjects in northern and southern China using Mann-Whitney U test or χ
2
test.

Results

Compared with subjects in southern China, those in northern China had significantly greater areas for lumen (57.7±14.9 mm
2
vs 50.4±18.3 mm
2
, p=0.009), wall (38.4±13.1 mm
2
vs 31.9±11.7 mm
2
, p<0.001) and total vessel (96.1±20.2 mm
2
vs 82.4±22.7 mm
2
, p=0.001) and mean wall thickness (1.25±0.43 mm vs 1.13±0.40 mm, p=0.019). χ
2
analysis showed that subjects in northern China tended to have a higher prevalence of intraplaque haemorrhage (14.3% vs 5.4%, p=0.106) and high-risk plaque (20.6% vs 10.7%, p=0.140) than those in southern China, although these differences were not statistically significant (all p>0.05).

Conclusion
Subjects in northern China have significantly larger vessel size and may have a higher prevalence of vulnerable plaques than those in southern China. Our findings provide additional perspective to optimise the management of cerebrovascular disease in individuals in different regions in China.

Trial registration number

NCT02017756
Polymorphic tachycardia in an anaesthetised horse with an undiagnosed pheochromocytoma undergoing emergency coeliotomy
Authors: Ranninger Elisabeth , Bettschart‐Wolfensberger Regula 
Published: January 2020

A 17‐year‐old, 550‐kg, neutered male Oldenburger horse was referred for an exploratory coeliotomy after acute collapse, profuse sweating and abdominal pain refractory to conventional analgesics. Clinical evaluation was only possible under sedation and revealed pale mucous membranes, tachypnoea, tachycardia with irregular heart rhythm and distended small intestines with decreased motility. Preoperative blood testing revealed severe hyperlactataemia and hyperglycaemia, whereas an abdominocentesis showed evidence of haemoperitoneum. Under general anaesthesia, polymorphic tachyarrhythmias, hypotension, peripheral oedema, persistent hyperlactataemia, electrolyte imbalances and haemorrhage complicated the anaesthetic management of this case. Despite cardiovascular support, including administration of fluid therapy, inotropes, 3.5 litres of fresh whole blood and 5 litres of fresh frozen plasma, the horse did not recover from general anaesthesia. A pheochromocytoma of the left adrenal gland with parenchymal rupture and haemorrhage was diagnosed postmortem. The present report describes the anaesthetic challenges of an undiagnosed pheochromocytoma in a horse with colic.
Gluon TMDs and NRQCD matrix elements in $${J}{/}{\psi }$$ production at an EIC
Authors: Bacchetta Alessandro , Boer Daniël , Pisano Cristian , Taels Pieter 
Published: January 2020

AbstractIn this paper we analyze azimuthal asymmetries in the processes of unpolarized and polarized$$J/\psi \,(\Upsilon )$$J/ψ(Υ)production at an Electron-Ion Collider. Apart from giving access to various unknown gluon transverse momentum distributions, we suggest to use them as a new method to extract specific color-octet NRQCD long-distance matrix elements, i.e.$$\langle 0\vert \mathcal{O}_{8}^{J/\psi }(^{1}S_{0})\vert 0\rangle $$⟨0|O8J/ψ(1S0)|0⟩and$$\langle 0\vert \mathcal{O}_{8}^{J/\psi }(^{3}P_{0})\vert 0\rangle $$⟨0|O8J/ψ(3P0)|0⟩, whose values are still quite uncertain and for which lattice calculations are unavailable. The new method is based on combining measurements of analogous asymmetries in open heavy-quark pair production which can be performed at the same energy. We also study for the first time the effects of transverse-momentum smearing in the quarkonium formation process. To enhance the gluon contribution one can consider smaller values ofxand, in order to assess the impact of small-xevolution, we perform a numerical study using the MV model as a starting input and evolve it with the JIMWLK equations.
Interaction between Graphene Oxide and the Mycelia ofMorchella sextelata
Authors: Tan Renhao , Li Jiwei , Zhou Li , Zhou Lu , Lei Jia , He Xinsheng , Zhu Wenkun 
Published: January 2020

Graphene oxide (GO) is expected to be harmful to the environment due to the toxicity. Accordingly, this work aimed to assess the potential harm of GO to the environment by investigating the toxicity of GO to the M. sextelata, and the effects of M. sextelata to GO. The dry weights, IR spectra, morphology, ultra-structures of mycelia, pH, conductivities of culture media, the activity of superoxide dismutase (SOD) and malondialdehyde (MDA) contents were measured to display the potential hazards of GO to M. sextelata. Then the Raman spectroscopy, dispersibility, and X-ray photoelectron spectroscopy (XPS) of GO were measured to show the effect of M. sextelata on GO. The results indicated that the lower GO concentrations promoted the growth of M. sextelata while the high level of GO inhibited the growth process of M. sextelata. After 7 d of culture, the effect was suppressive, with the biomass significantly reduced by 10.10%, the MDA content of G200 increased by 69.06%. GO nanosheets covered the surface of mycelia which caused change of the mycelial microstructures. Correspondingly, M. sextelata induces more defects in GO, accompanied by poor dispersion of GO in ethanol. Based on the XPS analysis, in the G10, G50 and G200 treatments, their atomic percentage of nitrogen in GO increased by 3.03%, 4.28% and 2.2%, respectively, and the atomic percentage of oxygen in GO reduced by 8.61%, 9.42% and 4.09%, respectively. The effect of mycelia on GO is mainly in deoxygenated and nitrogen-doped. We expected that the above results would provide a reference for the environmental hazard of GO.
Why clear communication means aiming for the lowest common denominator---and then some
Authors: Yaffe Philip 
Published: January 2020

Each "Communication Corner" essay is self-contained; however, they build on each other. For best results, before reading this essay and doing the exercise, go to the first essay "How an Ugly Duckling Became a Swan," then read each succeeding essay.
If you say something the audience doesn't understand, you will lose some (if not all) of their attention---especially when discussing complex subjects. Limiting the assumptions you make about your readers' level of understanding is a key element to good writing.
Overcoming Adaptive Resistance to KRAS Inhibitors Through Vertical Pathway Targeting
Authors: Yaeger Rona , Solit David B. 
Published: January 2020

Abstract

KRAS G12C inhibitors have shown promise in KRAS G12C–mutant lung cancer but intrinsic and acquired resistance are common. Cotreatment with inhibitors of the protein phosphatase SHP2 can abrogate the adaptive response of cancer cells to KRAS inhibitors resulting in greater suppression of MAPK signaling and enhanced tumor growth inhibition.
See related article by Ryan et al., p. 1633