bluuebunny/crossref_metadata_2025_split huggingface dataset:
Translingual Affairs of World Literature
Authors: De Donno Fabrizio 
Published: November 2020

Abstract
This essay explores a number of texts of the exophonic, or non-native literary production, respectively in Italian and German, of translingual authors Jhumpa Lahiri and Yoko Tawada. While the paper looks at how their dominant languages, respectively English and Japanese, continue to play a role in these writers’ non-native production, it focuses on the different approaches the two authors adopt to translingualism and the “linguistic family romance” metaphor, which they equally employ in highly imaginative ways in order to address both their condition of rootlessness and their attitudes to the notion of “mother tongue.” The essay argues that while Lahiri seems to remain a writer that does not contaminate languages (she is a writer in English, a writer in Italian, and a translator of Italian literature into English), Tawada brings German and Japanese together and dwells on the space of contamination between them in her production in German (and Japanese).
Reckoning with Race and Performing the Good News
Authors: Bacote Vincent E. 
Published: November 2020

Abstract
The “good news” is central to evangelical theology and the movement known as evangelicalism, but the news has not always been good for minorities who inhabit evangelical communities and institutions in the United States. Vincent Bacote argues a reckoning with questions of race is necessary for evangelical theology to help cultivate an evangelical movement more hospitable to minorities, particularly African-Americans. Evangelicalism is here regarded not only as a set of beliefs about the Bible, Christ’s work on the cross, conversion and witness but also as a set of dispositions and postures that create openness to the concerns of minorities. With a perpetually uneasy conscience, Christians within the evangelical movement can cultivate a disposition ready to learn from the questions and contributions of minorities in evangelical spaces, such as William Bentley and Carl Ellis. A better evangelical theology is proposed as doctrines that yield actions that are truly good news for all.
Developing the Juramento into an Evidence-Based Brief Intervention: A Brief Report
Authors: Garcia Victor , Lambert Emily , Heckert Alex , Pinchi Nahomy Hidalgo 
Published: November 2020

Introduction: This brief report recommends how the effectiveness of the juramento, a practice found in Mexican Catholicism, can be enhanced by combining it with Screening, Brief Intervention, and Referral to Treatment. The juramento is a grassroots intervention around a sacred pledge made to Our Lady of Guadalupe to abstain from alcohol from 6 months to 1 year. Method: The recommendations are made possible from an ongoing qualitative study on the use of the juramento among Mexican immigrant farmworkers in southeastern Pennsylvania. The subsample for this report is 15 Mexican immigrant farmworkers who made a juramento and two priests who administer the intervention. Results: Adding the Alcohol Use Disorders Identification Test and a referral to treatment in the counseling session of the juramento keeps its religious and cultural appeal. The core of the intervention—the ritualized pledge to Our Lady of Guadalupe—remains intact. Conclusion: Approaching the juramento with an evidence-based brief intervention lens will expand the availability of culturally based interventions to include a grassroots intervention in the Mexican immigrant community. The juramento is organic, rooted in culture and religion, making it more likely that it will help in reducing alcohol use disorders, especially those with strong religiosity.
Neglected extra-articular manifestations in rheumatoid arthritis patients with normal body mass index: reduced skeletal muscle overlapping overfat
Authors: Lin Jian-Zi , Chen Chu-Tao , Ma Jian-Da , Mo Ying-Qian , Li Qian-Hua , Chen Le-Feng , Yang Ze-Hong , Cheng Wan-Mei , He Xiao-Ling , Zheng Dong-Hui , Dai Lie 
Published: November 2020

Background: Chronic inflammation in rheumatoid arthritis (RA) can induce reduced muscle mass (myopenia) and ectopic fat deposition probably showing normal body mass index (BMI). We aimed to investigate their body composition (BC) characteristics and clinical significance. Methods: BMI and BC were collected in consecutive RA patients and control subjects. Myopenia was defined by appendicular skeletal muscle mass index (ASMI) ⩽7.0 kg/m2 in men and ⩽5.7 kg/m2 in women. Overfat was defined by body fat percentage (BF%) as ⩾25% for men and ⩾35% for women. Results: There were 620 RA patients (57.6% with normal BMI) and 2537 control subjects (62.5% with normal BMI) recruited. After 1:1 age and sex matching with control subjects, RA patients with normal BMI ( n = 240) showed significantly higher prevalence of myopenia (43.3% versus 22.1%) and overfat (19.2% versus 7.1%) as well as myopenia overlapping overfat (17.1% versus 3.3%). In all RA patients with normal BMI ( n = 357), there were 18.2% patients with myopenia overlapping overfat who had the worst radiographic scores and highest rates of previous glucocorticoid treatment and hypertension. Compared with those without, normal BMI RA patients with previous glucocorticoid treatment (24.4% versus 10.3%) or hypertension (27.8% versus 13.6%) had a higher rate of myopenia overlapping overfat. Previous glucocorticoid treatment [odds ratio (OR) = 2.844, 95% confidence interval (CI) 1.441–5.614] and hypertension (OR = 2.452, 95% CI 1.283–4.685) were potential associated factors of myopenia overlapping overfat in RA patients with normal BMI. Conclusion: Myopenia overlapping overfat is an important extra-articular manifestation which should not be ignored in RA patients with normal BMI, especially with glucocorticoid treatment and hypertension.
Use of hospital resources in the care of patients with intermediate risk pulmonary embolism
Authors: Sullivan Alexander E , Holder Tara , Truong Tracy , Green Cynthia L , Sofela Olamiji , Dahhan Talal , Granger Christopher B , Jones W Schuyler , Patel Manesh R 
Published: November 2020

Abstract

Background
Risk stratification and management of hemodynamically stable pulmonary embolism remains challenging. Professional societies have published stratification schemes, but little is known about the management of patients with intermediate risk pulmonary embolism. We describe the care of these patients at an academic health system.

Methods
Patient encounters from 1 January 2016 to 30 June 2017 were retrospectively identified utilizing a multihospital, electronic health record-based data warehouse. Using the 2019 European Society of Cardiology criteria, differences in hospital resource utilization, defined as intensive care unit admission, use of invasive therapies, and length of stay, were examined in patients with intermediate risk characteristics.

Results
A cohort of 322 intermediate risk patients, including 165 intermediate–low and 157 intermediate–high risk patients, was identified. Intermediate–high risk patients more often underwent catheter-directed therapy (14.0% vs. 1.8%; P &lt; 0.001) compared to intermediate–low risk patients and had a 50% higher rate of intensive care unit admission (relative risk 1.50; 95% confidence interval 1.06, 2.12; P = 0.023). There was no difference in median intensive care unit length of stay (2.7 vs. 2.0 days; P = 0.761) or hospital length of stay (5.0 vs. 5.0 days; P = 0.775) between intermediate–high risk and intermediate–low risk patients. Patients that underwent invasive therapies had a 3.8-day shorter hospital length of stay (beta –3.75; 95% confidence interval –6.17, –1.32; P = 0.002).

Conclusion
This study presents insights into the hospital resource utilization of patients with intermediate risk pulmonary embolism. The 2019 European Society of Cardiology risk stratification criteria are a clinically relevant scheme that identifies patients more often treated with intensive care unit admission and advanced therapies.
Estimation of daily sodium and potassium excretion from overnight urine of Japanese children and adolescents
Authors: Okuda Masayuki , Asakura Keiko , Sasaki Satoshi 
Published: November 2020

Abstract
Background
Estimates of daily sodium (Na) and potassium (K) excretion were explicitly biased when using equations for adults. We aimed to develop equations to estimate them using overnight urine from Japanese children and adolescents.

Methods
The subjects comprised 70 students aged 10.49–15.76 years: validation group, n = 34; and verification group, n = 36. Each subject performed two operations of overnight spot urine (Um) and 24-h urine (U24) sampling. Concentrations of Na, K, and creatinine (Cr) were measured, and anthropometrics were recorded. In the validation group, Na/Cr, and K/Cr (mEq L−1/mg dL−1) in 24-h urine were predicted from their correspondents in overnight urine. Daily Cr excretion (EstCr24; mg d−1) was estimated according to Mage’s method.

Results
In validation, we formulated Na excretion (mg d−1) = 23 × exp (0.2085) × [(Na/CrUm + 1)1.0148 − 1] × 1.078 × EstCr24/10; and K excretion (mg d−1) = 39 × exp (0.0315) × [(K/CrUm + 1)1.3165 − 1] × 1.078 × EstCr24/10. For verification, we compared estimates with the measured 24-h Na excretion 3596 ± 1058 mg d−1, and K excretion 1743 ± 569 mg d−1. The mean biases and intraclass correlations (3, 1) were −131 mg d−1 and 0.60, respectively for Na excretion; and −152 mg d−1 and 0.55 for K excretion.

Conclusion
We obtained validated equations to estimate daily Na and K excretion with accessible variables such as Na, K, and Cr concentrations of overnight urine, body height and weight, and age for children and adolescents. When using the obtained equations, caution should be paid to small but definite biases and measurement errors.
Effects of the built environment on physical activity: a systematic review of longitudinal studies taking sex/gender into account
Authors: Tcymbal Antonina , Demetriou Yolanda , Kelso Anne , Wolbring Laura , Wunsch Kathrin , Wäsche Hagen , Woll Alexander , Reimers Anne K. 
Published: November 2020

Abstract
Background
Individual health behavior is related to environmental and social structures. To promote physical activity (PA) effectively, it is necessary to consider structural influences. Previous research has shown the relevance of the built environment. However, sex/gender differences have yet not been considered. The aim of this systematic review was to identify built environmental determinants of PA by taking sex/gender into account.

Methods
A systematic literature search was carried out using six electronic databases (PubMed, CINAHL, SportDiscus, PsycInfo, Scopus, Web of Knowledge) to identify studies analyzing the effect of changes in the built environment on PA, taking sex/gender into account. To be included, studies had to be based on quantitative data and a longitudinal study design. Changes in the built environment had to be objectively assessed. The methodological quality of the studies was examined using the QualSyst tool for examining risk of bias.

Results
In total, 36 studies published since 2000 were included in this review. The data synthesis revealed that the majority of reviewed studies found the built environment to be a determinant of PA behavior for both, males and females, in a similar way. Creating a new infrastructure for walking, cycling, and public transportation showed a positive effect on PA behavior. Findings were most consistent for the availability of public transport, which was positively associated with overall PA and walking. The improvement of walking and cycling infrastructure had no effect on the overall level of PA, but it attracted more users and had a positive effect on active transportation. In women, the availability of public transport, safe cycling lanes, housing density, and the distance to daily destinations proved to be more relevant with regard to their PA behavior. In men, street network characteristics and road environment, such as intersection connectivity, local road density, and the presence of dead-end roads, were more important determinants of PA.

Conclusion
This review sheds light on the relevance of the built environment on PA. By focusing on sex/gender differences, a new aspect was addressed that should be further analyzed in future research and considered by urban planners and other practitioners.
Employing waterborne autonomous vehicles for museum visits: a case study in Amsterdam
Authors: Rong Helena Hang , Tu Wei , Duarte Fábio , Ratti Carlo 
Published: November 2020

AbstractAmsterdam is a culturally rich city attracting millions of tourists. Popular activities in Amsterdam consist of museum visits and boat tours. By strategically combining them, this paper presents an innovative approach using waterborne autonomous vehicles (WAVs) to improve the museum visitation in Amsterdam. Multi-source urban data including I Amsterdam card data and Instagram hashtags are used to reveal museum characteristics such as offline and online popularity of museums and visitation patterns. A multi-objective model is proposed to optimize WAV routes by considering museum characteristics and travel experiences. An experiment in the Amsterdam Central area was conducted to evaluate the viability of employing WAVs. By comparing WAVs with land transportation, the results demonstrate that WAVs can enhance travel experience to cultural destinations. The presented innovative WAVs can be extended to a larger variety of points of interest in cities. These findings provide useful insights on embracing artificial intelligence in urban tourism.
Advances and perspectives in selecting resistance traits against the parasitic mite Varroa destructor in honey bees
Authors: Guichard Matthieu , Dietemann Vincent , Neuditschko Markus , Dainat Benjamin 
Published: November 2020

Abstract
Background
In spite of the implementation of control strategies in honey bee (Apis mellifera) keeping, the invasive parasitic mite Varroa destructor remains one of the main causes of colony losses in numerous countries. Therefore, this parasite represents a serious threat to beekeeping and agro-ecosystems that benefit from the pollination services provided by honey bees. To maintain their stocks, beekeepers have to treat their colonies with acaricides every year. Selecting lineages that are resistant to infestations is deemed to be a more sustainable approach.

Review
Over the last three decades, numerous selection programs have been initiated to improve the host–parasite relationship and to support honey bee survival in the presence of the parasite without the need for acaricide treatments. Although resistance traits have been included in the selection strategy of honey bees, it has not been possible to globally solve the V. destructor problem. In this study, we review the literature on the reasons that have potentially limited the success of such selection programs. We compile the available information to assess the relevance of selected traits and the potential environmental effects that distort trait expression and colony survival. Limitations to the implementation of these traits in the field are also discussed.

Conclusions
Improving our knowledge of the mechanisms underlying resistance to V. destructor to increase trait relevance, optimizing selection programs to reduce environmental effects, and communicating selection outcomes are all crucial to efforts aiming at establishing a balanced relationship between the invasive parasite and its new host.
Identification of QTLs conferring resistance to scald (Rhynchosporium commune) in the barley nested association mapping population HEB-25
Authors: Büttner Bianca , Draba Vera , Pillen Klaus , Schweizer Günther , Maurer Andreas 
Published: November 2020

Abstract
Background
Barley scald, caused by the fungus Rhynchosporium commune, is distributed worldwide to all barley growing areas especially in cool and humid climates. Scald is an economically important leaf disease resulting in yield losses of up to 40%. To breed resistant cultivars the identification of quantitative trait loci (QTLs) conferring resistance to scald is necessary. Introgressing promising resistance alleles of wild barley is a way to broaden the genetic basis of scald resistance in cultivated barley. Here, we apply nested association mapping (NAM) to map resistance QTLs in the barley NAM population HEB-25, comprising 1420 lines in BC1S3 generation, derived from crosses of 25 wild barley accessions with cv. Barke.

Results
In scald infection trials in the greenhouse variability of resistance across and within HEB-25 families was found. NAM based on 33,005 informative SNPs resulted in the identification of eight reliable QTLs for resistance against scald with most wild alleles increasing resistance as compared to cv. Barke. Three of them are located in the region of known resistance genes and two in the regions of QTLs, respectively. The most promising wild allele was found at Rrs17 in one specific wild donor. Also, novel QTLs with beneficial wild allele effects on scald resistance were detected.

Conclusions
To sum up, wild barley represents a rich resource for scald resistance. As the QTLs were linked to the physical map the identified candidate genes will facilitate cloning of the scald resistance genes. The closely linked flanking molecular markers can be used for marker-assisted selection of the respective resistance genes to integrate them in elite cultivars.
Identification and population genetic analyses of copy number variations in six domestic goat breeds and Bezoar ibexes using next-generation sequencing
Authors: Guo Jiazhong , Zhong Jie , Liu George E. , Yang Liu , Li Li , Chen Guangling , Song Tianzeng , Zhang Hongping 
Published: November 2020

AbstractBackgroundCopy number variations (CNVs) are a major form of genetic variations and are involved in animal domestication and genetic adaptation to local environments. We investigated CNVs in the domestic goat (Capra hircus) using Illumina short-read sequencing data, by comparing our lab data for 38 goats from three Chinese breeds (Chengdu Brown, Jintang Black, and Tibetan Cashmere) to public data for 26 individuals from three other breeds (two Moroccan and one Chinese) and 21samples from Bezoar ibexes.ResultsWe obtained a total of 2394 CNV regions (CNVRs) by merging 208,649 high-confidence CNVs, which spanned ~ 267 Mb of total length and accounted for 10.80% of the goat autosomal genome. Functional analyses showed that 2322 genes overlapping with the CNVRs were significantly enriched in 57 functional GO terms and KEGG pathways, most related to the nervous system, metabolic process, and reproduction system. Clustering patterns of all 85 samples generated separately from duplications and deletions were generally consistent with the results from SNPs, agreeing with the geographical origins of these goats. Based on genome-wideFSTat each CNV locus, some genes overlapping with the highly divergent CNVs between domestic and wild goats were mainly enriched for several immunity-related pathways, whereas the genes overlapping with the highly differentiated CNVs between highland and lowland goats were mainly related to vitamin and lipid metabolism. Remarkably, a 507-bp deletion at ~ 14 kb downstream ofFGF5on chromosome 6 showed highly divergent (FST = 0.973) between the highland and lowland goats. Together with an enhancer activity of this sequence shown previously, the function of this duplication in regulating fiber growth deserved to be further investigated in detail.ConclusionWe generated a comprehensive map of CNVs in goats. Many genetically differentiated CNVs among various goat populations might be associated with the population characteristics of domestic goat breeds.
Molecular convergent and parallel evolution among four high-elevation anuran species from the Tibetan region
Authors: Lu Bin , Jin Hong , Fu Jinzhong 
Published: November 2020

AbstractBackgroundTo date, evidence for the relative prevalence or rarity of molecular convergent and parallel evolution is conflicting, and understanding of how these processes contribute to adaptation is limited. We compared four high-elevation anuran species (Bufo tibetanus,Nanorana parkeri,Rana kukunorisandScutiger boulengeri) from the Tibetan region, and examined convergent and parallel amino acid substitutions between them and how they may have contributed to high-elevation adaptation.ResultsGenomic data of the four high-elevation species and eight of their low-elevation close relatives were gathered. A total of 1098 orthologs shared by all species were identified. We first conducted pairwise comparisons using Zhang and Kumar’s test. Then, theRconvindex was calculated and convergence/divergence correlation plotting was conducted. Furthermore, genes under positive selection and with elevated evolutionary rate were examined. We detected a large number of amino acid sites with convergent or parallel substitutions. Several pairs of high-elevation species, in particular,R. kukunorisvsN. parkeriandB. tibetanusvsS. boulengeri, had excessive amounts of convergent substitutions compared to neutral expectation. Nevertheless, these sites were mostly concentrated in a small number of genes (3–32), and no genome-wide convergence was detected. Furthermore, the majority of these convergent genes were neither under detectable positive selection nor had elevated evolutionary rates, although functional prediction analysis suggested some of the convergent genes could potentially contribute to high-elevation adaptation.ConclusionsThere is a substantial amount of convergent evolution at the amino-acid level among high-elevation amphibians, although these sites are concentrated in a few genes, not widespread across the genomes. This may attribute to the fact that all the target species are from the same environment. The relative prevalence of convergent substitutions among high-elevation amphibians provides an excellent opportunity for further study of molecular convergent evolution.
Feasibility and validity of Ecological Momentary Assessment in patients with acute coronary syndrome
Authors: Jean François A. M. , Sibon Igor , Husky Mathilde , Couffinhal Thierry , Swendsen Joel 
Published: November 2020

Abstract
Background
In recent years, Ecological Momentary Assessment (EMA) has expanded rapidly in healthcare research but its application specifically to the field of cardiology has been limited. This study presents essential information concerning the feasibility and validity of EMA in patients with acute coronary syndrome.

Methods
Four months after a first-ever acute coronary syndrome, 47 patients completed EMA five times a day for seven consecutive days concerning their current activities, mood and perceived negativity or positivity of daily events.

Results
Compliance with the repeated electronic assessments was high, and no evidence was found for time-dependent biases such as fatigue or practice effects. The resulting EMA data were found to have high internal validity, high reliability when considering average scores, and low reliability when considering within-person variance.

Conclusions
We found evidence for the feasibility and intrinsic validity of EMA in patients with acute coronary syndrome. Research examining daily life experiences, symptoms and therapeutic adherence in this population can be reinforced through the use of mobile technologies.