bluuebunny/crossref_metadata_2025_split huggingface dataset:
O SABER REFLEXIVO-COLABORATIVO NO ENSINO E APRENDIZAGEM DE PORTUGUÊS LÍNGUA ESTRANGEIRA: significados construídos na interação do par mais experiente com o professor em formação
Authors: Gómez Marina Ayumi Izaki , Viana Nelson 
Published: April 2020

Um dos grandes desafios na formação de professores é lidar com o distanciamento entre teoria e prática (LEFFA, 2006). Esse tema tem sido foco de discussão promovida por diversos autores da área de ensino de línguas, o que corrobora a sua relevância investigativa. No que se refere à área de Português Língua Estrangeira (PLE), mesmo com a crescente demanda pela aprendizagem do idioma por estrangeiros, “chama a atenção o fato de haver ainda tão pouca pesquisa na área de formação do professor de PLE” (DUTRA, 2010, p.13). Levando em consideração a escassez de estudos sobre a formação desse profissional, objetivamos neste artigo apresentar e discutir significados construídos na interação do par mais experiente com professores em formação que compuseram parte dos resultados obtidos em pesquisa de doutorado. Os aportes reflexivo e sociocultural fundamentaram o estudo. Criar oportunidades para que o professor em formação possa discutir sua prática e a de seus colegas é imprescindível para desenvolver o processo reflexivo sobre o dizer e o fazer pedagógicos e o par mais experiente como mediador dessa ação pode potencialmente colaborar para construção de percepção crítica. Sob o paradigma qualitativo de base etnográfica e interpretativista foram analisadas interações, envolvendo professores em formação e um par mais experiente, priorizando-se o processo de construção de significados acerca da reflexão sobre a prática. Os professores em formação (graduandos em Letras) ministraram cursos de PLE, vinculados a Projeto de Extensão do Departamento de Letras de uma universidade pública do interior paulista. O par mais experiente é professora e pesquisadora da referida área. Com base nos resultados alcançados, concluímos que a ação de pelo menos um par mais experiente tem potencial para auxiliar os professores de PLE na construção de reflexão de modo colaborativo por meio da interação. Como desdobramentos dessa pesquisa de doutorado, foi proposto um organograma base (incluído neste artigo), de trabalho colaborativo em PLE e do Saber Reflexivo-Colaborativo, na formação de professores.
The re‐occurrence of cardiomyopathy in propionic acidemia after liver transplantation
Authors: Berry Gerard T. , Blume Elizabeth D. , Wessel Ann , Singh Tajinder , Hecht Leah , Marsden Deborah , Sahai Inderneel , Elisofon Scott , Ferguson Michael , Kim Heung Bae , Harris David J. , Demirbas Didem , Almuqbil Mohammed , Nyhan William L. 
Published: April 2020

AbstractCardiomyopathy is a frequent complication of propionic acidemia (PA). It is often fatal, and its occurrence is largely independent of classic metabolic treatment modalities. Liver transplantation (LT) is a treatment option for severe PA as the liver plays a vital role in metabolism of the precursors that accumulate in patients with PA. LT in PA is now considered to be a long‐lasting and valid treatment to prevent cardiac disease. The subject of this report had severe cardiomyopathy that largely disappeared prior to undergoing a LT. Three years following the transplant, there was recurrence of cardiomyopathy following a surgery that was complicated with a postoperative aspiration pneumonia. On his last hospital admission, he was presented with pulmonary edema and heart failure. He continued with episodes of intractable hypotension, despite maximum inotropic and diuretic support. He died following redirection of care. We conclude that lethal cardiomyopathy may develop several years after successful LT in patients with PA.
Dry season circulation‐type classification applied to precipitation and temperature in the Peruvian Andes
Authors: Bonshoms Martí , Álvarez‐Garcia Francisco J. , Ubeda Jose , Cabos William , Quispe Kelita , Liguori Giovanni 
Published: April 2020

AbstractWe present the first systematic classification of circulation regimes that characterize the Tropical Andes during the dry season (May–August). We apply the hierarchical k‐means clustering method to ERA‐Interim reanalysis data of daily mean geopotential height at 500‐ and 200‐hPa levels for the period 1981–2015. Specifically, by combining the variability in intensity and location of geopotential anomalies we identify 12 circulation types (CTs). We then establish the relationship between the CTs and surface conditions in the Peruvian Andes (PA) analysing high‐resolution gridded datasets of daily mean temperature and rainfall. Our results indicate that intense precipitations and low minimum temperatures are often associated with an Upper Tropospheric Trough (UTT) centred at subtropical latitudes (~30°S) and between 80° and 70°W of longitude. Moreover, drier and warmer conditions across the entire PA region are largely associated with three anticyclonic CTs. Strong negative anomalies in daily maximum (minimum) temperatures can be related to the effect of day (night) cloudiness in the radiative balance, but also to subtropical cold air advections favoured by the UTT. While CTs featuring warmer (colder) conditions have become more (less) frequent in the last decades of the record, there is no systematic link between positive or negative trends in occurrence and the wetter and drier character of the CTs. The annual frequencies of 10 CTs are significantly correlated with El Niño‐Southern Oscillation, with warmer and drier (cooler and wetter) CTs generally preceded by an El Niño (La Niña) in the previous wet season.
Frequency‐swept high‐repetition rate optical source
Authors: Finot Christophe 
Published: April 2020

AbstractWe propose and numerically validate an all‐optical scheme to generate optical pulse trains with varying temporal pulse‐to‐pulse delay and pulse duration. Our simulations confirm that applying a temporal sinusoidal phase modulation followed by a shaping of the spectral phase is efficient to maintain high‐quality Gaussian temporal profiles.
A density functional theory study of the stereoselectivity of Cu(OTf)2‐catalyzed [3+2] cycloaddition of trifluoromethylated N‐acylhydrazones and isoprene: A concerted asynchronous mechanism
Authors: Tang Jing , Xu Dong‐Hui , Wang Xin , Li Laicai , Liu Xiang‐Yang , Su Xin‐Tong , Guo Jianmin , Zhai Bin 
Published: April 2020

AbstractHere we employ density functional theory calculations to systematically investigate the underlying mechanism of Cu(OTf)2‐catalyzed [3+2] cycloaddition reactions in the synthesis of CF3‐substituted pyrazolidines. About eight possible initial configurations of the [3+2] reaction is considered, and all relevant reactants, transition states, and products are optimized. Based on these structures, internal reaction coordinate paths, and wavefunction analysis results, we conclude that the Cu(OTf)2‐catalyzed [3+2] cycloaddition follows a concerted asynchronous mechanism. The CN bond forms immediately after the formation of the CC bond. Among the eight reaction paths, the energy barrier for the [3+2] reaction that leads to the CF3‐substituted syn‐pyrazolidine is the lowest, ∼5.4 kcal/mol, which might result in the diastereoselectivity that is observed in the experiment. This work not only gives the detailed mechanism of the Cu(OTf)2‐catalyzed [3+2] cycloaddition but can also be helpful for the future designation of Cu(OTf)2‐based cycloaddition processes.
Early life exposures and risk of adult respiratory disease during 50 years of follow-up
Authors: Johansson Carl J. , Nilsson Peter M. , Ignell Claes 
Published: April 2020

AbstractAdult health is influenced by factors during fetal life affecting organ development and birth weight. We aimed to study such factors in relation to adult respiratory disease (ARD) risk. The Helsingborg Birth Cohort, Sweden, contributed baseline data collected by medical staff through clinical examination and questionnaires on maternal and birth characteristics 1964–1967. Register linkages were performed with completions of data on ARD by ICD 8–10 classifications (1969–2016), and/or ARD-related drug usage (2005–2016) enabling a 50-year follow-up time. Cox proportional hazard regression analyses were made to adjust for potential confounders, adjusted hazard ratio (aHR). A total of 3675 mothers and their offspring were included. Female offspring showed higher frequency of ARD than males, aHR 1.5 (95% CI 1.3–1.8). Maternal use of sedatives during second trimester, aHR 2.2 (95% CI 1.4–3.4), and maternal smoking during most of pregnancy, aHR 1.2 (95% CI 1.0–1.4), were associated with offspring ARD. Stratified by sex, large-for-gestational-age, aHR 1.4 (95% CI 1.0–1.9), was significantly associated with ARD in female offspring along with maternal sedative use during second trimester and maternal smoking during most of pregnancy. Maternal sedative use during second trimester or all trimesters were the only significant risk factors for male offspring. In conclusion, maternal sedative use in second trimester was independently associated with subsequent respiratory disease in adult offspring irrespective of sex.
Assessment by Comparative Judgement: An Application to Secondary Statistics and English in New Zealand
Authors: Marshall Neil , Shaw Kirsten , Hunter Jodie , Jones Ian 
Published: April 2020

AbstractThere is growing interest in using comparative judgement to assess student work as an alternative to traditional marking. Comparative judgement requires no rubrics and is instead grounded in experts making pairwise judgements about the relative ‘quality’ of students’ work according to a high level criterion. The resulting decision data are fitted to a statistical model to produce a score for each student. Cited benefits of comparative judgement over traditional methods include increased reliability, validity and efficiency of assessment processes. We investigated whether such claims apply to summative statistics and English assessments in New Zealand. Experts comparatively judged students’ responses to two national assessment tasks, and the reliability and validity of the outcomes were explored using standard techniques. We present evidence that the comparative judgement process efficiently produced reliable and valid assessment outcomes. We consider the limitations of the study, and make suggestions for further research and potential applications.
Distribution and Properties of Magnetic Flux Ropes in Titan's Ionosphere
Authors: Martin C. J. , Arridge C. S. , Badman S. V. , Russell C. T. , Wei H. 
Published: April 2020

AbstractTitan's magnetic environment is a dynamic and unique place. We detect 85 flux ropes during all the Cassini flybys of Titan from 2005–2017. Analysis describing the location of flux ropes in Titan's ionosphere as well as where Titan is in Saturn's magnetosphere shows that the flux ropes are more often found when Titan is in the noon sector of Saturn's magnetosphere. A secondary peak of occurrence is found in the postmidnight area, where it is expected that Saturn's magnetosphere is highly dynamic. We also find that the flux rope occurrence is correlated with the average electron density profile of Titan's ionosphere. A force‐free model is utilized to estimate the radii and core magnetic field strength of the flux ropes. We find a large range of radii from 150–500 km with a small number of very large flux ropes (500–1,000 km) and a range of core field strengths of 1–15 nT, again with some much larger values(20–40 nT). The model also shows that more flux ropes are right‐handed than left‐handed in twist; however, we are unable to determine if there is a physical reason or if this is due to an observer bias. Additionally, we evaluate the goodness of fit for the model in each instance and conclude that, on average, the flux ropes may be better represented by a non‐force‐free model.
Ultrafast optical integration and pattern classification for neuromorphic photonics based on spiking VCSEL neurons
Authors: Robertson Joshua , Hejda Matěj , Bueno Julián , Hurtado Antonio 
Published: April 2020

AbstractIn today’s data-driven world, the ability to process large data volumes is crucial. Key tasks, such as pattern recognition and image classification, are well suited for artificial neural networks (ANNs) inspired by the brain. Neuromorphic computing approaches aimed towards physical realizations of ANNs have been traditionally supported by micro-electronic platforms, but recently, photonic techniques for neuronal emulation have emerged given their unique properties (e.g. ultrafast operation, large bandwidths, low cross-talk). Yet, hardware-friendly systems of photonic spiking neurons able to perform processing tasks at high speeds and with continuous operation remain elusive. This work provides a first experimental report of Vertical-Cavity Surface-Emitting Laser-based spiking neurons demonstrating different functional processing tasks, including coincidence detection and pattern recognition, at ultrafast rates. Furthermore, our approach relies on simple hardware implementations using off-the-shelf components. These results therefore hold exciting prospects for novel, compact and high-speed neuromorphic photonic platforms for future computing and Artificial Intelligence systems.
Video-Assisted Thoracic Surgery in Early Stage of Pediatric Pleural Empyema Improves Outcome
Authors: Pogorelić Zenon , Bjelanović Dora , Gudelj Ružica , Jukić Miro , Petrić Jasna , Furlan Dubravko 
Published: April 2020

Abstract
Objectives The aim of this study was to observe outcomes of early decortication in a treatment of pleural empyema using video-assisted thoracoscopic surgery (VATS).
Methods The case records of 21 pediatric patients who underwent VATS for empyema between 2009 and 2019 were retrospectively reviewed. Patients were observed based on demographic, laboratory, and clinical data, as well as treatment outcomes.
Results Out of a total of 59 patients treated for pleural empyema, 21 (10 male and 11 female) children with a median age of 5 years (interquartile range [IQR] 2.8; 6.0) received VATS. The empyema was classified as stage I in 2 patients (9.5%), stage II in 4 patients (19%), and stage III in 15 patients (71.5%). Median surgical time was 60 minutes (IQR 50; 90). There were 2 (9.5%) postoperative complications and 1 recurrence (4.8%). Children treated in stages I and II showed significantly better postoperative results compared with the children treated in stage III. Length of hospital stay (8 vs. 10 days; p = 0.01), length of intensive care unit stay (1 vs. 5 days; p < 0.001), duration of chest tube drainage (4 vs. 6 days; p = 0.043), duration of postoperative fever (1.5 vs. 4 days; p = 0.001), and surgical time (40 vs. 70 minutes; p < 0.001) were significantly shorter in children operated in stages I and II than in stage III.
Conclusion Early decortication using a VATS is a successful, effective, and easily performed surgical method in the treatment of pediatric pleural empyema, as well as a method that significantly improves recovery time and shortens the hospital stay.
Exercise restriction is protective for genotype-positive family members of arrhythmogenic right ventricular cardiomyopathy patients
Authors: Wang Weijia , Tichnell Crystal , Murray Brittney A , Agafonova Julia , Cadrin-Tourigny Julia , Chelko Stephen , Tandri Harikrishna , Calkins Hugh , James Cynthia A 
Published: April 2020

Abstract

Aims
In arrhythmogenic right ventricular cardiomyopathy (ARVC) patients, exercise worsens disease course, so exercise restriction is recommended. However, recommendations for genotype-positive ARVC family members is incompletely resolved. We aimed to provide evidence for exercise recommendations for genotype-positive ARVC family members.

Methods and results
Arrhythmogenic right ventricular cardiomyopathy family members inheriting a pathogenic desmosomal variant were interviewed about exercise history from age 10. Exercise was characterized by duration, intensity, and dose (duration*intensity). Associations between exercise and (i) diagnosis by 2010 Task Force Criteria and (ii) development of sustained ventricular arrhythmias were examined. The study included 101 family members (age: 40.5 ± 19.3 years, male: 41%, Plakophilin-2 variant: 81%). Forty-four individuals (44%) met diagnostic criteria and 16 (16%) experienced sustained ventricular arrhythmia. Individuals who met diagnostic criteria had significantly higher average exercise duration and dose, but not peak intensity than those who did not. Only one individual who exercised below the American Heart Association recommended minimum (650 metabolic equivalent of task-hours/year) met diagnostic criteria or experienced sustained ventricular arrhythmia as opposed to 50% of individuals who exceeded it (adjusted odds ratio = 0.03, 95% confidence interval 0.003–0.26). The difference in exercise exposure between affected and unaffected individuals was more striking in females than in males. Females who had done high-dose exercise in adolescence had the worst survival free from diagnosis (P &lt; 0.01).

Conclusions
In phenotype-negative ARVC family members with a pathogenic desmosomal variant, athletic activities should be limited, particularly exercise dose. Exercise may play a greater role in promoting disease in female family members.
Optimized Model Parameterization using Compact Full Waveform Inversion
Authors: Xu Linan , Manukyan Edgar , Maurer Hansruedi 
Published: April 2020

Summary
Seismic Full Waveform Inversion (FWI) has the potential to produce high-resolution subsurface images, but the computational resources required for realistically sized problems can be prohibitively large. In terms of computational costs, Gauss-Newton algorithms are more attractive than the commonly employed conjugate gradient methods, because the former have favorable convergence properties. However, efficient implementations of Gauss-Newton algorithms require an excessive amount of computer memory for larger problems. To address this issue, we introduce Compact Full Waveform Inversion (CFWI). Here, a suitable inverse model parameterization is sought that allows representing all subsurface features, potentially resolvable by a particular source-receiver deployment, but using only a minimum number of model parameters. In principle, an inverse model parameterization, based on the Eigenvalue decomposition, would be optimal, but this is computationally not feasible for realistic problems. Instead, we present two alternative parameter transformations, namely the Haar and the Hartley transformations, with which similarly good results can be obtained. By means of a suite of numerical experiments, we demonstrate that these transformations allow the number of model parameters to be reduced to only a few percent of the original parameterization without any significant loss of spatial resolution. This facilitates efficient solutions of large-scale FWI problems with explicit Gauss-Newton algorithms.
The single-sided pulsator CO Camelopardalis
Authors: Kurtz D W , Handler G , Rappaport S A , Saio H , Fuller J , Jacobs T , Schmitt A , Jones D , Vanderburg A , LaCourse D , Nelson L , Kahraman Aliçavuş F , Giarrusso M 
Published: April 2020

ABSTRACT
CO Cam (TIC 160268882) is the second ‘single-sided pulsator’ to be discovered. These are stars where one hemisphere pulsates with a significantly higher amplitude than the other side of the star. CO Cam is a binary star comprised of an Am δ Sct primary star with Teff = 7070 ± 150 K, and a spectroscopically undetected G main-sequence secondary star. The dominant pulsating side of the primary star is centred on the L1 point. We have modelled the spectral energy distribution combined with radial velocities, and independently the TESS light curve combined with radial velocities. Both of these give excellent agreement and robust system parameters for both stars. The δ Sct star is an oblique pulsator with at least four low radial overtone (probably) f modes with the pulsation axis coinciding with the tidal axis of the star, the line of apsides. Preliminary theoretical modelling indicates that the modes must produce much larger flux perturbations near the L1 point, although this is difficult to understand because the pulsating star does not come near to filling its Roche lobe. More detailed models of distorted pulsating stars should be developed. These newly discovered single-sided pulsators offer new opportunities for astrophysical inference from stars that are oblique pulsators in close binary stars.
Infrared luminosity functions and dust mass functions in the EAGLE simulation
Authors: Baes Maarten , Trčka Ana , Camps Peter , Trayford James , Katsianis Antonios , Marchetti Lucia , Theuns Tom , Vaccari Mattia , Vandenbroucke Bert 
Published: April 2020

ABSTRACT
We present infrared luminosity functions and dust mass functions for the EAGLE cosmological simulation, based on synthetic multiwavelength observations generated with the SKIRT radiative transfer code. In the local Universe, we reproduce the observed infrared luminosity and dust mass functions very well. Some minor discrepancies are encountered, mainly in the high luminosity regime, where the EAGLE-SKIRT luminosity functions mildly but systematically underestimate the observed ones. The agreement between the EAGLE-SKIRT infrared luminosity functions and the observed ones gradually worsens with increasing lookback time. Fitting modified Schechter functions to the EAGLE-SKIRT luminosity and dust mass functions at different redshifts up to z = 1, we find that the evolution is compatible with pure luminosity/mass evolution. The evolution is relatively mild: within this redshift range, we find an evolution of L⋆,250 ∝ (1 + z)1.68, L⋆,TIR ∝ (1 + z)2.51 and M⋆,dust ∝ (1 + z)0.83 for the characteristic luminosity/mass. For the luminosity/mass density we find ε250 ∝ (1 + z)1.62, εTIR ∝ (1 + z)2.35, and ρdust ∝ (1 + z)0.80, respectively. The mild evolution of the dust mass density is in relatively good agreement with observations, but the slow evolution of the infrared luminosity underestimates the observed luminosity evolution significantly. We argue that these differences can be attributed to increasing limitations in the radiative transfer treatment due to increasingly poorer resolution, combined with a slower than observed evolution of the SFR density in the EAGLE simulation and the lack of AGN emission in our EAGLE-SKIRT post-processing recipe.
Zebra2: advanced and easy-to-use web-server for bioinformatic analysis of subfamily-specific and conserved positions in diverse protein superfamilies
Authors: Suplatov Dmitry , Sharapova Yana , Geraseva Elizaveta , Švedas Vytas 
Published: April 2020

Abstract
Zebra2 is a highly automated web-tool to search for subfamily-specific and conserved positions (i.e. the determinants of functional diversity as well as the key catalytic and structural residues) in protein superfamilies. The bioinformatic analysis is facilitated by Mustguseal—a companion web-server to automatically collect and superimpose a large representative set of functionally diverse homologs with high structure similarity but low sequence identity to the selected query protein. The results are automatically prioritized and provided at four information levels to facilitate the knowledge-driven expert selection of the most promising positions on-line: as a sequence similarity network; interfaces to sequence-based and 3D-structure-based analysis of conservation and variability; and accompanied by the detailed annotation of proteins accumulated from the integrated databases with links to the external resources. The integration of Zebra2 and Mustguseal web-tools provides the first of its kind out-of-the-box open-access solution to conduct a systematic analysis of evolutionarily related proteins implementing different functions within a shared 3D-structure of the superfamily, determine common and specific patterns of function-associated local structural elements, assist to select hot-spots for rational design and to prepare focused libraries for directed evolution. The web-servers are free and open to all users at https://biokinet.belozersky.msu.ru/zebra2, no login required.