bluuebunny/crossref_metadata_2025_split huggingface dataset:
Energy, environment and economic analyses of a parabolic trough concentrating photovoltaic/thermal system
Authors: Alayi Reza , Kumar Ravinder , Seydnouri Syed Reza , Ahmadi Mohammad Hossein , Issakhov Alibek 
Published: October 2020

AbstractThe present study deals with the techno-economic and environmental analysis of a parabolic trough concentrating photovoltaic/thermal system. Energy, economic and environmental issues of the purposed system have been evaluated and analyzed. The MATLAB software has been used for modeling. The outputs of this software include the amount of energy and electrical productions as well as environmental parameters for different studied areas. Finally, economic analysis and energy savings have been performed to persuade the use of this type of technology to supply the various loads of a building. One of the most important results of this study is the production of 222 060 kW of thermal and electrical energy in Bushehr, which is the largest amount of production among cities and saves energy and revenue from the sale of this amount of energy—231 983 kW and 38 533.24$, respectively. A comparative environmental analysis represents that the largest prevention of CO2 emissions is found in Bushehr with 515 tons per year and the lowest prevention of CO2 is related to Rasht with 34 tons.
Antidepressive Effect of Antipsychotics in the Treatment of Schizophrenia: Meta-Regression Analysis of Randomized Placebo-Controlled Trials
Authors: Miura Itaru , Nosaka Tadashi , Yabe Hirooki , Hagi Katsuhiko 
Published: October 2020

Abstract

Background
Antipsychotics improve the positive symptoms of schizophrenia. However, little is known about the extent of antidepressive effects of antipsychotics and their correlation with effects on other symptom domains in schizophrenia. The aim was to investigate whether antidepressive effects of antipsychotics have a significant correlation with the effects on specific symptom domains of schizophrenia.

Methods
Electronic databases were searched to identify eligible studies that reported antidepressive effects of antipsychotics for the treatment of adult patients with schizophrenia in double-blind, randomized placebo-controlled trials (RCTs). Mean change from baseline in depressive symptoms was meta-analyzed, and the correlation with the effects on other symptom domains was examined through meta-regression analysis.

Results
Thirty-five RCTs (13 890 patients) were included in this meta-analysis. Overall, antipsychotics showed greater efficacy than placebo in reducing depressive symptoms, with small to medium effect sizes (standardized mean difference = −0.27, 95% confidence interval −0.32 to −0.22, P &lt; .001). All the antipsychotics, except for chlorpromazine, haloperidol, and ziprasidone, were associated with significantly greater decreases in depressive symptoms compared with placebo (standardized mean difference = −0.19 to −0.40). A higher antidepressive effect was significantly correlated with a higher improvement in Positive and Negative Syndrome Scale/Brief Psychiatric Rating Scale total, positive, and negative, and Positive and Negative Syndrome Scale-general psychopathology symptoms (β = .618, P &lt; .001; β = .476, P &lt; .001; β = .689, P &lt; .001; β = .603, P &lt; .001, respectively).

Conclusions
Second-generation antipsychotics (except for ziprasidone) were associated with small to medium effects sizes on improvement in depressive symptoms among adult patients with schizophrenia. The antidepressive effect of antipsychotics was significantly correlated with improvement in other symptom domains, with the highest correlation observed for improvement in negative symptoms.

PROSPERO registration number
CRD42019133015
Long-term efficacy of dolutegravir plus lamivudine for maintenance of HIV viral suppression in adults with and without historical resistance to lamivudine: Week 96 results of ART-PRO pilot study
Authors: Rial-Crestelo David , de Miguel Rosa , Montejano Rocío , Dominguez-Dominguez Lourdes , Aranguren-Rivas Paula , Esteban-Cantos Andrés , Bisbal Otilia , Santacreu-Guerrero Mireia , Garcia-Alvarez Mónica , Alejos Belén , Hernando Asunción , Bermejo-Plaza Laura , Cadiñanos Julen , Mayoral Mario , Castro Juan Miguel , Moreno Victoria , Martin-Carbonero Luz , Delgado Rafael , Rubio Rafael , Pulido Federico , Arribas José Ramón ,   ART-PRO, Arribas J R , Buckley R De Miguel , Montejano R , Esteban-Cantos A , Stella-Ascariz N , Cadiñanos J , Mayoral M , Castro J M , Moreno V , Martin-Carbonero L , Valencia E , Bernardino I , Busca C , Micán R , Pérez-Valero I , González J , Montes ML , Centeno J Rodríguez ,   PI16/00837-PI16/00678 study group, Pulido F , Rial-Crestelo D , Dominguez-Dominguez L , Aranguren-Rivas P , Bisbal O , Plaza L Bermejo , Garcia-Alvarez M , Santacreu-Guerrero M , de Lagarde M , Matarranz M , Luzckoviak J , Sotillo A , Delgado R , Rubio R 
Published: October 2020

Abstract

Background
In the ART-PRO pilot trial there were no virological failures through 48 weeks of treatment with dolutegravir plus lamivudine in suppressed individuals with and without archived lamivudine resistance-associated mutations (RAMs) detected through next-generation sequencing (NGS) but without evidence of lamivudine RAMs in baseline proviral DNA population sequencing.

Objectives
To present 96 week results from ART-PRO.

Methods
Open-label, single-arm pilot trial. At baseline, all participants switched to dolutegravir plus lamivudine. Participants were excluded if proviral DNA population genotyping detected lamivudine RAMs. To detect resistance minority variants, proviral DNA NGS was retrospectively performed from baseline samples. For this analysis the efficacy endpoint was the proportion of participants with &lt;50 HIV-1 RNA copies/mL at week 96. Safety and tolerability outcomes were incidence of adverse events and treatment discontinuations.

Results
Forty-one participants were included, 21 with lamivudine RAMs in historical plasma RNA genotypes. Baseline proviral DNA NGS detected lamivudine RAMs (M184V/I and/or K65R/E/N) above a 5% threshold in 71.4% (15/21) and 15% (3/20) of participants with and without history of lamivudine resistance, respectively. At 96 weeks, 90.2% of participants achieved the efficacy endpoint. Between week 48 and 96 there was one discontinuation due to consent withdrawal and no discontinuations related to adverse events. Two participants had a transient viral rebound, both re-suppressed on dolutegravir plus lamivudine. Through week 96, there were no virological failures.

Conclusions
In this pilot trial, dolutegravir plus lamivudine maintained virological suppression at 96 weeks despite historical lamivudine resistance and persisting archived minority lamivudine RAMs.
Evaluation of Two-Leaf Sampling Units to Estimate Sugarcane Aphid (Hemiptera: Aphididae) Economic Thresholds in Commercial Grain Sorghum
Authors: Lindenmayer Jessica C , Payton Mark , Giles Kris L , Elliott Norman C , Knutson Allen E , Bowling Robert , Seiter Nicholas J , McCornack Brian , Brown Sebe A , Royer Tom A 
Published: October 2020

Abstract
Sugarcane aphid Melanaphis sacchari Zehntner is a significant economic pest of grain sorghum in the United States. Effective monitoring and early detection are cornerstones for managing invasive pests. The recently developed binomial sequential sampling plan estimates sugarcane aphid economic thresholds (ETs) based on classification whether a 2-leaf sample unit has ≤ or ≥ 50 M. sacchari. In this study, we evaluated eight 2-leaf sampling units for potential use in the sequential sampling plan. From 2016 through 2017, whole plant counts of M. sacchari were recorded non-destructively in situ on sorghum plants from 140 fields located in five states. Plant canopies were stratified into three categories. Two leaves from each stratum were used to compare linear relationships between M. sacchari numbers per two-leaf sample unit and total M. sacchari density per plant. Analysis revealed that two randomly selected leaves from the middle stratum accounted more variation for estimating M. sacchari density when compared to two leaves from the other strata. Comparison of eight two-leaf sampling units within plant growth stages were variable in quantifying variation of M. sacchari densities. When growth stages were combined, the standard uppermost + lowermost leaf sample unit and a unit consisting of two randomly selected leaves from the middle stratum revealed little difference in their enumeration of variation in M. sacchari density. Because other sample units were either less predictive and/or more variable in estimating M. sacchari density, we suggest that the (L1+U1) sample unit remain the preferred method for appraising M. sacchari ETs.
Effects of Human Settlements and Spatial Distribution of Wing Vein Length, Wing Fray Categories and Hunger Stages in Glossina morsitans morsitans (Diptera: Glossinidae) and Glossina pallidipes (Diptera: Glossinidae) in Areas Devoid of Cattle in North-Eastern Zambia
Authors: Chilongo Kalinga , Manyangadze Tawanda , Mukaratirwa Samson 
Published: October 2020

Abstract
The effect of human-associated habitat degradation on tsetse populations is well established. However, more insights are needed into how gradual human encroachment into tsetse fly belts affect tsetse populations. This study investigated how wing vein length, wing fray categories, and hunger stages, taken as indicators of body size, age, and levels of access to hosts, respectively, in Glossina morsitans morsitans Westwood (Diptera: Glossinidae) and Glossina pallidipes Austen (Diptera: Glossinidae), varied along a transect from the edge into inner parts of the tsetse belt, in sites that had human settlement either concentrated at the edge of belt or evenly distributed along transect line, in north-eastern Zambia. Black-screen fly round and Epsilon traps were used in a cross-sectional survey on tsetse flies at three sites, following a transect line marked by a road running from the edge into the inner parts of the tsetse belt, per site. Two sites had human settlement concentrated at or close to the edge of the tsetse belt, whereas the third had human settlement evenly distributed along the transect line. Where settlements were concentrated at the edge of tsetse belt, increase in distance from the settlements was associated with increase in wing vein length and a reduction in the proportion of older, and hungry, tsetse flies. Increase in distance from human settlements was associated with improved tsetse well-being, likely due to increase in habitat quality due to decrease in effects of human activities.
Antimullerian Hormone as a Serum Biomarker for Risk of Chemotherapy-Induced Amenorrhea
Authors: Ruddy Kathryn J , Schaid Daniel J , Batzler Anthony , Cecchini Reena S , Partridge Ann H , Norman Aaron , Fehrenbacher Louis , Stewart Elizabeth A , Trabuco Emanuel , Ginsburg Elizabeth , Couch Fergus J , Fasching Peter A , Vachon Celine , Ganz Patricia A 
Published: October 2020

Abstract
Antimullerian hormone (AMH) is a promising biomarker for ovarian reserve. In this study, we assessed AMH before and 1 year after initiation of adjuvant chemotherapy on National Surgical Adjuvant Breast and Bowel Project (NSABP)/NRG Oncology B-47 in female participants aged 42 years and younger (median age = 39 years). At baseline, median AMH was 1.2 ng/mL; 13 (4.7%) values were less than 0.1 ng/mL (the threshold for detectable levels, in the perimenopause and menopause range), and 57 values (20.6%) were less than 0.5 ng/mL. At 1 year, 215 (77.6%) were less than 0.1 ng/mL, and 264 (95.3%) were less than 0.5 ng/mL. Postchemotherapy menses were reported by 46.2% of participants. Multivariable logistic regression found that the odds of having postchemotherapy menses increased with younger age, higher body mass index, and higher prechemotherapy AMH, but not by trastuzumab administration or by the choice of chemotherapy (doxorubicin-cyclophosphamide followed by paclitaxel vs docetaxel-cyclophosphamide). We conclude that higher prechemotherapy AMH predicts a lower risk of chemotherapy-induced amenorrhea and that AMH 1 year after chemotherapy initiation is not informative in this setting because it is likely to be very low.
Minimally invasive esophagectomy with intrathoracic anastomosis in a situs inversus totalis patient
Authors: Meng Yunchong , Xiao Han , Zhang Zheng , Li Kuo , Huang Quanfu , Qiu Wenlin , Liao Yongde 
Published: October 2020

Abstract
Situs inversus totalis (SIT) is a rare congenital condition, which is characterized by abnormal placement of the thoracic and abdominal organs. The incidence of this condition is estimated to be from 1/8000 to 1/25,000. There have been minimal reports on SIT patients with esophageal cancer. In this report, we discuss a patient with SIT complicated by middle and lower esophageal cancer who underwent laparoscopic and thoracoscopic esophagectomy with intrathoracic anastomosis, and provide useful information with regards to treatment of this rare condition.
Two new cases of pediatric tumoral calcinosis
Authors: Rajaonarison Ny Ony Narindra Lova Hasina , Nirinaharimanitra Vatosoa Sarobidy , Hunald Francis Allen , Ahmad Ahmad 
Published: October 2020

Abstract
Tumoral calcinosis (TC) is a rare benign pathology, particularly in pediatrics. It is difficult to diagnose with its pathophysiology poorly understood. We report two pediatric cases of TC having benefited from radiological assessments and surgical excision. Final diagnosis was made by pathological examination. For the two cases, no sign of recurrence was noted ~30 months of follow-up.
CRISPR-Based Approaches for Efficient and Accurate Detection of SARS-CoV-2
Authors: Zhang Wancun , Liu Kangbo , Zhang Pin , Cheng Weyland , Li Linfei , Zhang Fan , Yu Zhidan , Li Lifeng , Zhang Xianwei 
Published: October 2020

AbstractAn outbreak of COVID-19, caused by infection with SARS-CoV-2 in Wuhan, China in December 2019, spread throughout the country and around the world, quickly. The primary detection technique for SARS-CoV-2, the reverse-transcription polymerase chain reaction (RT-PCR)–based approach, requires expensive reagents and equipment and skilled personnel. In addition, for SARS-CoV-2 detection, specimens are usually shipped to a designated laboratory for testing, which may extend the diagnosis and treatment time of patients with COVID-19. The latest research shows that clustered regularly interspaced short palindromic repeats (CRISPR)–based approaches can quickly provide visual, rapid, ultrasensitive, and specific detection of SARS-CoV-2 at isothermal conditions. Therefore, CRISPR-based approaches are expected to be developed as attractive alternatives to conventional RT-PCR methods for the efficient and accurate detection of SARS-CoV-2. Recent advances in the field of CRISPR-based biosensing technologies for SARS-CoV-2 detection and insights into their potential use in many applications are reviewed in this article.
Turbulent dissipation, CH+ abundance, H2 line luminosities, and polarization in the cold neutral medium
Authors: Moseley Eric R , Draine B T , Tomida Kengo , Stone James M 
Published: October 2020

ABSTRACT
In the cold neutral medium, high out-of-equilibrium temperatures are created by intermittent dissipation processes, including shocks, viscous heating, and ambipolar diffusion. The high-temperature excursions are thought to explain the enhanced abundance of CH+ observed along diffuse molecular sightlines. Intermittent high temperatures should also have an impact on H2 line luminosities. We carry out simulations of magnetohydrodynamic (MHD) turbulence in molecular clouds including heating and cooling, and post-process them to study H2 line emission and hot-gas chemistry, particularly the formation of CH+. We explore multiple magnetic field strengths and equations of state. We use a new H2 cooling function for $n_{\text{H}}\le 10^5\, {\text{cm}}^{-3}$, $T\le 5000\, {\text{K}}$, and variable H2 fraction. We make two important simplifying assumptions: (i) the H2/H fraction is fixed everywhere and (ii) we exclude from our analysis regions where the ion–neutral drift velocity is calculated to be greater than 5 km s−1. Our models produce H2 emission lines in accord with many observations, although extra excitation mechanisms are required in some clouds. For realistic root-mean-square (rms) magnetic field strengths (≈10 μG) and velocity dispersions, we reproduce observed CH+ abundances. These findings contrast with those of Valdivia et al. (2017) Comparison of predicted dust polarization with observations by Planck suggests that the mean field is ≳5 µG, so that the turbulence is sub-Alfvénic. We recommend future work treating ions and neutrals as separate fluids to more accurately capture the effects of ambipolar diffusion on CH+ abundance.
Binary population synthesis with probabilistic remnant mass and kick prescriptions
Authors: Mandel Ilya , Müller Bernhard , Riley Jeff , de Mink Selma E , Vigna-Gómez Alejandro , Chattopadhyay Debatri 
Published: October 2020

ABSTRACT
We report on the impact of a probabilistic prescription for compact remnant masses and kicks on massive binary population synthesis. We find that this prescription populates the putative mass gap between neutron stars and black holes with low-mass black holes. However, evolutionary effects reduce the number of X-ray binary candidates with low-mass black holes, consistent with the dearth of such systems in the observed sample. We further find that this prescription is consistent with the formation of heavier binary neutron stars such as GW190425, but overpredicts the masses of Galactic double neutron stars. The revised natal kicks, particularly increased ultra-stripped supernova kicks, do not directly explain the observed Galactic double neutron star orbital period–eccentricity distribution. Finally, this prescription allows for the formation of systems similar to the recently discovered extreme mass ratio binary GW190814, but only if we allow for the survival of binaries in which the common envelope is initiated by a donor crossing the Hertzsprung gap, contrary to our standard model.
The orbital evolution of UFDs and GCs in an evolving Galactic potential
Authors: Armstrong Benjamin M , Bekki Kenji , Ludlow Aaron D 
Published: October 2020

ABSTRACT
We use the second Gaia data release to investigate the kinematics of 17 ultra-faint dwarf galaxies (UFDs) and 154 globular clusters (GCs) in the Milky Way, focusing on the differences between static and evolving models of the Galactic potential. An evolving potential modifies a satellite’s orbit relative to its static equivalent, though the difference is small compared to existing uncertainties on orbital parameters. We find that the UFD Boötes II is likely on its first passage around the Milky Way. Depending on the assumed mass of the Milky Way, the UFDs Triangulum II, Hydrus I, Coma Berenices, Draco II, and Ursa Major II, as well as the GC Pyxis, may also be on first infall so may be useful for constraining the mass of the Galaxy. We identify a clear kinematic distinction between metal-rich ([Fe/H] &gt; −1.1) and metal-poor GCs ([Fe/H] ≤ −1.1). Although most metal-rich clusters occupy predominately prograde orbits, with low eccentricities (e ≈ 0.35) and similar specific angular momenta and orbital planes as the Galactic disc, seven show potentially retrograde orbits, the origin of which is unclear. Metal-poor clusters have more diverse orbits, higher eccentricities (e ≈ 0.65), and half of them have orbital planes offset from the disc by 60° to 120°—twice as many as the metal-poor GCs. The UFDs have similar θ and ϕ to the metal-poor GCs, suggesting a similar origin. We provide a catalogue of orbital parameters for UFDs and GCs for two different Galaxy masses and their observational uncertainties.
Non-Piecemeal Pluralism
Authors: Miller Elizabeth 
Published: October 2020

Abstract
I argue that Schaffer fails to provide a non-question-begging argument for priority monism. Despite his suggestion to the contrary, Humean pluralists need not, and plausibly do not, endorse his tiling constraint on metaphysically basic objects. Moreover, the distinction between supervenience—of the sort at issue in Humean doctrine—and metaphysical necessitation—of the sort at issue in Schaffer’s tiling constraint—points toward an alternative treatment of the phenomena initially inspiring Schafferian monism. There is an important possibility, one that Humeans can or should embrace, that Schaffer overlooks when drawing his monistic conclusion.
Lepus europaeus(Lagomorpha: Leporidae)
Authors: Bock Anni 
Published: October 2020

AbstractLepus europaeus Pallas, 1778, commonly called the European hare, is one of 32 species of Lepus. It is widely distributed in Europe and Asia where it was not native but introduced by humans for sport. L. europaeus does not burrow, nor hibernate, and gives birth to precocial young (leverets). It prefers open grassland, fields, agricultural farmland, and pastures with hedgerows and bushes. Declining populations in several countries since the 1960s led to increased research to investigate the reasons; L. europaeus is considered threatened in several countries, but of “Least Concern” by the International Union for Conservation of Nature and Natural Resources.
OrthoDB in 2020: evolutionary and functional annotations of orthologs
Authors: Zdobnov Evgeny M , Kuznetsov Dmitry , Tegenfeldt Fredrik , Manni Mosè , Berkeley Matthew , Kriventseva Evgenia V 
Published: October 2020

AbstractOrthoDB provides evolutionary and functional annotations of orthologs, inferred for a vast number of available organisms. OrthoDB is leading in the coverage and genomic diversity sampling of Eukaryotes, Prokaryotes and Viruses, and the sampling of Bacteria is further set to increase three-fold. The user interface has been enhanced in response to the massive growth in data. OrthoDB provides three views on the data: (i) a list of orthologous groups related to a user query, which are now arranged to visualize their hierarchical relations, (ii) a detailed view of an orthologous group, now featuring a Sankey diagram to facilitate navigation between the levels of orthology, from more finely-resolved to more general groups of orthologs, as well as an arrangement of orthologs into an interactive organism taxonomy structure, and (iii) we added a gene-centric view, showing the gene functional annotations and the pair-wise orthologs in example species. The OrthoDB standalone software for delineation of orthologs, Orthologer, is freely available. Online BUSCO assessments and mapping to OrthoDB of user-uploaded data enable interactive exploration of related annotations and generation of comparative charts. OrthoDB strives to predict orthologs from the broadest coverage of species, as well as to extensively collate available functional annotations, and to compute evolutionary annotations such as evolutionary rate and phyletic profile. OrthoDB data can be assessed via SPARQL RDF, REST API, downloaded or browsed online from https://orthodb.org.