bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transcriptome Analysis Reveals the Long Intergenic Noncoding RNAs Contributed to Skeletal Muscle Differences between Yorkshire and Tibetan Pig
Authors: Huang Ziying , Li Qianqian , Li Mengxun , Li Changchun 
Published: February 2020

Abstract
Background The difference between the skeletal muscle growth rates of Western and domestic breeds is remarkable, but the potential regulatory mechanism involved is still unclear. Numerous studies have pointed out that long intergenic noncoding RNA (lincRNA) plays a key role in skeletal muscle development. This study used published Yorkshire (LW) and Tibetan pig (TP) transcriptome data to explore the possible role of lincRNA in the difference in skeletal muscle development between the two breeds. Results Through differential expression analysis, 138 differentially expressed lincRNAs (DELs) were obtained between the two breeds, and their potential target genes (PTGs) were predicted. The results of Gene Ontology and pathway analysis revealed that PTGs are involved in multiple biological processes and pathways related to muscle development. The quantitative trait loci (QTLs) of DELs were predicted, and the results showed that most QTLs are related to muscle development. Finally, we constructed a co-expression network between muscle development related PTGs (MDRPTGs) and their corresponding DELs on the basis of their expression levels. The expression of DELs was significantly correlated with the corresponding MDRPTGs. Also, multiple MDRPTGs are involved in the key regulatory pathway of muscle fiber hypertrophy, which is the IGF-1-AKT-mTOR pathway. Conclusions In summary, multiple lincRNAs that may cause differences in skeletal muscle development between the two breeds were identified, and their possible regulatory roles were explored. The findings of this study may provide a valuable reference for further research on the role of lincRNA in skeletal muscle development.
Copeptin and Nesfatin-1 are interesting interrelated biomarkers playing a role in the pathogenesis of insulin resistance in Chinese obese children
Authors: xiao yanfeng y , Yin Chunyan , Liu Weihua , Xu Erdi , Weicheng LV , Lu Qi 
Published: February 2020

Abstract
Background Recently, copeptin and nesfatin-1 have been identified as interesting novel peptides playing a role in the pathogenesis of obesity-related insulin resistance in adults, respectively. However, the relationship between them has not been elucidated; and their circulating levels in obese children have not been adequately studied. Therefore, the current study aimed to investigate whether their levels are altered in Chinese obese children and to study the correlation of these two peptides with each other and with insulin resistance and other biochemical parameters. Methods A total of 120 children were enrolled in this study, including 80 obese children and 40 lean controls. Anthropometric parameters and clinical data of all subjects were collected and circulating TNF-α, adiponectin, leptin, copeptin and nesfatin-1 levels were detected using enzyme-linked immunosorbent assays. Results Serum copeptin and nesfatin-1 levels were significantly elevated in obese children and children with insulin resistance compared to control subjects. In addition, nesfatin-1 and copeptin levels were found to be significantly positively correlated with one another in pearson’s correlation and partial correlation. More importantly, multiple regression analysis used nesfatin-1or copeptin as the dependent parameters and significant correlation between nesfatin-1 and copeptin with each other and the associations between each of them with HOMA-IR were detected. Conclusion These findings are novel and shed light on the possible interplay role of these two molecules in obesity-related insulin resistance.
Faculty Development Program effectiveness in educational events
Authors: Falavigna Asdrubal , GUIROY ALFREDO , Emmerich Juan , Miranda Diogo Julien 
Published: February 2020

Abstract
Background Developing clinical and biomedical science faculty to become effective teachers is critical to meet the challenges of medical education. Education research is at a stage in which we have strong theories of student learning, but we do not have well-developed ideas about teacher learning, nor about how to help teachers incorporate new ideas into their ongoing systems of practice. We aim to study the AOSpine Faculty Development program, which consists in a series of training programs at progressive levels. Methods Retrospective study from a prospective database. The information for Faculty performance (national, regional and international) in all AOSpine educational events from 2008 to 2016 was retrospectively reviewed. Additionally we developed a supplementary survey with the participants in 2016. It covered demographic topics and 4 specific questions regarding (1) quality expectations for CME programs, (2) AOSpine events highlights, (3) what could be improved in AOSpine events, and (4) activities of interest. Results We’ve accessed scores from 646 professionals (n=646) in 7,962 evaluations from 2008 to 2016 using a five-point Likert scale. 798 participants replied the 2016 survey from 20 countries of the region. The evaluation for a national Faculty was 4.42 points, the regional 4.56, and for the international faculty 4.53. The mean punctuation for the master course was 4.25, for advanced 4.44, and the value of 4.48 for principles. The Chair Training promoted an increase of the evaluation from 4.44 to 4.52 (p = 0.022) Conclusion The appliance of a Faculty Development Program based on educational strategies directly affects the outcomes of educational events. The 8-years systematic review showed continued improvement of the trained faculty evaluations in all levels.
Numerical study of magnetic particles mixing in waste water under an external magnetic field
Authors: Liosis Christos , Karvelas Evangelos G. , Karakasidis Theodoros , Sarris Ioannis E. 
Published: February 2020

Abstract
The combination of nanotechnology and microfluidics may offer an effective water and wastewater treatment. A novel approach combines the use of magnetic particles which can capture heavy metal impurities in microfluidic ducts. The purpose of this study is to investigate the mixing mechanism of two water streams, one with magnetic particles and the other with wastewater. The optimum mixing is obtained when particles are uniformly distributed along the volume of water in the duct for the combined action of a permanent, spatially and temporally aligned magnetic field. Results showed that mixing is enhanced as the frequency of the magnetic field decreases or its amplitude increases, while magnetic gradient is found to play an insignificant role in the present configuration. Moreover, for simulations with low frequency, the mean concentration of particles is found to be twice as high as compared to the cases with higher frequency. Optimum distribution of particles inside the micromixer is observed for the combination of 0.6 T, 8 T/m and 5 Hz for the magnetic magnitude, gradient and frequency, respectively, where concentration reaches the optimal value of 0.77 mg/mL along the volume of the duct.
Evaluation of a new X-band weather radar for operational use in south Sweden
Authors: Hosseini Seyyed Hasan , Hashemi Hossein , Berndtsson Ronny , South Nicholas , Aspegren Henrik , Larsson Rolf , Olsson Jonas , Persson Andreas , Olsson Lisa 
Published: February 2020

Abstract
The performance of a new type of X-band weather radar (WR) for Sweden during a pilot run is studied. Compared to the conventional C-band WRs, the X-band WR covers a smaller area but with a higher spatiotemporal resolution, making it suitable for urban hydrological applications. Rainfall estimations from different elevation angles of the radar (levels) are compared at one-minute and single-event timescales with the observations of several rain gauges at different ranges using hyetographs. In general, the estimations aligned well with observations and the best match appeared for ranges as long as 5–10 km. Seemingly, radar estimations suffered from overshooting of lower lying showers by higher level scans in longer ranges (19–30 km) and from the reflectivity contamination due to moving objects in short ranges (&lt;1 km). Also, the effective range of the radar dropped sharply for the moments when a cloudburst was located over the radar. Although various sources of error could affect the X-band WR rainfall estimates, higher resolution spatiotemporal rainfall monitoring for wider areas will benefit from an integration of data from a network of X-band WRs.
Use of Diffusion-Weighted Magnetic Resonance Imaging and Apparent Diffusion Coefficient in Gastric Cancer Staging
Authors: Soydan Levent , Demir Ali Aslan , Torun Mehmet , Cikrikcioglu Makbule Arar 
Published: February 2020

Background:
The apparent diffusion coefficient (ADC), the quantitative parameter of
diffusion-weighted magnetic resonance imaging (DW-MRI), is a measure for this restricted diffusion,
and its role in gastric cancer (GC) including distinguishing malignant segments from healthy
gastric wall, metastatic perigastric lymph nodes from benign nodes and evaluating response of GC
to neoadjuvant chemotherapy has been investigated in previous studies. Evidence suggests that
ADC may also be of help in assessment of aggressiveness and preoperative staging of gastric cancer,
which needs to be explored in further studies.

Objective:
To investigate the role of DW-MRI and its quantitative parameter, ADC in staging of
gastric cancer.

Methods:
Forty-six patients (28 male, 18 female, mean age 62 years) with non-metastatic biopsy-
proven GC who underwent abdominal DW-MRI before surgery were included in this retrospective
study. Tumor invasion depth (T-stage) and nodal involvement (N-stage) were evaluated using
signal increase on DW-MRI, and tumor ADC was measured. Diagnostic performance of these results
was assessed by comparing them with postsurgical histopathology based on 8th TNM classification.

Results:
Sensitivity, specificity, and accuracy of DW-MRI in T-staging were 92.1%, 75%, 89.1%
for ≤T2 vs. ≥T3; and 75%, 88.5%, 82.6% for ≤T3 vs. T4. However, sensitivity, specificity, and accuracy
of DW-MRI in N-staging were 89.3%, 88.9%, 89.1% for ≤N1 vs. ≥N2; and 73.7%, 96.3%,
86.9% for ≤N2 vs. N3, respectively. Relative preoperative ADC values correlated with pT staging
(r=-0.397, p=0.006). There was also a statistically significant difference of relative ADC values between
≤T3 and T4 stages, and a cut-off of 0.64 s/mm2 could differentiate these stages with an odds
ratio of 7.714 (95% confidence interval, 1.479-40.243). The area under the receiver operating characteristic
curve for differentiating ≤T3 and T4 stages was 0.725.

Conclusion:
DW-MRI may contribute to the clinical staging of non-metastatic GC. In particular,
relative ADC of DW-MRI can distinguish T4 gastric cancer from less advanced T-stages.
Squeezing Out and Characterization of Silicon from Sand by Mg- Thermite Reduction Process
Authors: Islam Mohammad Shoriful , Sattar Mohammad A. , Halim Mohammad A. , Hoque Mohammad Asadul , Quader Abdul , Gafur Mohammad A. , Hakim Mohammad A. 
Published: February 2020

Background:
Sand is one of the efficient sources of silicon. We get quite easily the
plethora of sand from the river side, Bangladesh. Utilization of the superfluous sand can be assisted to
enhance our economy.

Methods:
In this work, silicon is extracted from sand by metal–thermite reduction process and the sample of sand is collected from padma river Rajshahi, Bangladesh. The process is environmentally benign and low cost. The reduction of the sand was performed with Mg powder, and purification was done by leaching out with HCl and HF. We have studied the structural properties, chemical nature and physical morphology.

Results and Conclusion:
X-ray Diffraction (XRD) confirmed that the presence of elemental Si in the samples produced by Mg-thermite reduction process and the particle size was found 25.72±1.3 nm in an average. Surface morphology has been studied using Scanning Electron Microscopy (SEM) and the particle size seemed around 30 to 40 nm which was comparable to the obtained particle size from XRD. Fourier transform infrared spectroscopy (FTIR) showed the presence of Si-Si bonding in the investigating materials. The chemical nature of the sand has been studied by X-ray Fluorescence (XRF) analysis. Silicon content of sand was found about maximum 80%.
MANUAL MATERIAL HANDLING IN THE ‘KARUNG’ LIFTING PROCESS USING BIOMECHANIC AND PHYSIOLOGI APPROACH
Authors: Adiyanto Okka , Prasetyo Fajar Aji , Ramadhani Muhammad Faris Kautsar 
Published: February 2020

This study was aimed at minimizing musculoskeletal disorder (MSDs) in heavers on traditional markets by completing facilities and improving lifting techniques that are in accordance with ergonomic aspects. This research was conducted in traditional markets with heaver objects which are often carried out in the process of moving goods. This study used biomechanics and physiology methods to be able to analyze body posture so that it can prevent spinal damage. The data were then analyzed using Maximum Permissible Limit (MPL), which previously carried out data collection on the size of the body posture. The analysis of the results was done to determine the value of the compression force (FC). FC values are the basis for comparison with Action Limit (AL). The results show that FC values = 10,018,078N, FC> MPL. Importantly, the position of the heavers’ posture is at a dangerous level. Proposed improvements using a tool and after being developed again will result in changes in FC values to 3370.94, FC <AL means the position of the body in a safe condition. The results of this study are expected to provide an assessment that helps prevent spinal damage.MANUAL MATERIAL HANDLING PADA PROSES PENGANGKATAN KARUNG MENGGUNAKAN PENDEKATAN BIOMEKANIKA DAN FISIOLOGI Penelitian ini bertujuan untuk meminimumkan keluhan Musculoskeletal disorder (MSDs) pada pekerja kuli panggul di pasar tradisional dengan merancang fasilitas dan memperbaiki teknik memindahkan barang yang sesuai dengan aspek ergonomis. Penelitian ini dilakukan di pasar tradisional dengan objek kuli panggul yang sering melakukan proses pemindahan barang. Penelitian ini menggunakan metode pendekatan biomekanika dan fisiologi untuk dapat menganalisis postur tubuh sehingga dapat mencegah cedera tulang belakang. Data kemudian dianalisa menggunakan Maximum Permissible Limit (MPL) yang sebelumnya dilakukan pengambilan data ukuran postur tubuh pekerja tersebut. Analisis hasil dari perhitungan dilakukan untuk mengetahui nilai dari force compresion (FC). Nilai FC menjadi dasar untuk dibandingkan dengan Action Limit (AL). Hasil dari analisa didapat nilai FC = 10.018,078N, FC>MPL. Artinya, posisi postur tubuh pekerja dalam level berbahaya. Usulan perbaikan dengan menggunakan alat bantu dan setelah dianalisis kembali maka akan menghasilkan perubahan nilai FC menjadi 3370,94; FC< AL artinya posisi tubuh dalam keadaan aman. Hasil penelitian ini diharapkan dapat memberikan rekomendasi alat bantu sehingga dapat mencegah cedera tulang belakang.
THE EFFECT OF ADDITIVE COMBINATION AND Azotobacter sp. TOWARDS Glycine max. L. GROWTH
Authors: Alfani Yunia Vella , Suryatmana Pudjawati , Setiawan Ade 
Published: February 2020

This study was aimed at determining the increasing of growth and production of soybean crops by giving Azotobacter sp. and additive materials such as coconut water, molasses, and bran. This research was conducted on Januari 2018 to April 2018 at Ciparanje Experimental Field Faculty of Agriculture. Universitas Padjadjaran, Jatinangor, Sumedang, West Java Province, on ± 774 meters above sea level (asl) using single factor randomized block design with 10 treatments; Azotobacter sp. and additive materials combination such as coconut water, molasses, and bran in three repetitions. The observations on the parameters observed in the final vegetative phase were on plant height, chlorophyll content, and population of Azotobacter sp. using Total Plate Count (TPC) method.The results show that the application of combination additives materials and Azotobacter sp. effect on populations Azotobacter sp., chlorophyll content, plant height and number of soybean pods (Glycine max L.). Application of coconut water independently, water added with Azotobacter sp., and combination of additive with Azotobacter sp. can give the best effect to the content of chlorophyll, plant height, and soybean crops components (Glycine max. L.).PENGARUH KOMBINASI BAHAN ADITIF DAN Azotobacter sp. TERHADAP PERTUMBUHAN Glycine max. L.Penelitian ini bertujuan untuk mengetahui pertumbuhan dan produksi tanaman kedelai dengan memberikan Azotobacter sp. dan aditif air kelapa, molase, serta dedak. Penelitian ini dilaksanakan pada Januari 2018-April 2018 di Kebun Percobaan Ciparanje Fakultas Pertanian Universitas Padjadjaran, Jawa Barat pada ± 774 meter di atas permukaan laut (dpl). Penelitian ini menggunakan rancangan acak kelompok dengan 10 perlakuan pemberian Azotobacter sp. dan aditif air kelapa, molase, serta dedak dengan tiga ulangan. Pengamatan terhadap parameter yang diamati pada fase vegetatif akhir yaitu tinggi tanaman, kandungan klorofil, dan populasi Azotobacter sp. dengan metode Total Plate Count (TPC). Hasil penelitian menunjukkan aplikasi kombinasi bahan aditif dan penambahan pupuk hayati Azotobacter sp. berpengaruh terhadap populasi Azotobacter sp., kadar klorofil, tinggi tanaman dan jumlah polong tanaman kedelai (Glycine max L.). Aplikasi air kelapa secara mandiri, air kelapa yang ditambahkan dengan Azotobacter sp., dan kombinasi bahan aditif dengan Azotobacter sp. dapat memberikan pengaruh terbaik terhadap kandungan klorofil, tinggi tanaman, dan komponen hasil tanaman kedelai (Glycine max. L.).
THE EFFECT OF MICRO PARTICLE STEEL SLAG ON P-RETENTION AND PH ON ANDISOL
Authors: Rostini Ai Ening , Devnita Rina , Mulyani Oviyanti , Joy Benny 
Published: February 2020

This study was aimed at determining the effect of microparticles steel slag towards P retention, soil acidity in Andisol from Ciater, West Java. The research was conducted in November 2017 until January 2018. The andisol was taken from the PTPN XIII-Ciater Tea Plantation, Subang, while steel slag was obtained from PT. Krakatau Steel Indonesia. The study used a Completely Randomized Design consisting of 11 treatments and 3 replications so that the total of all treatments was 33 experimental polybags. The treatments given were 500 mesh steel slag and 1.7 µm steel slag. The incubation media were stored in the Soil Physics Laboratory of the Faculty of Agriculture at UNPAD for 2 months. The observed parameters were P retention analyzed by the Blakemore method and soil pH which was analyzed by the electrometry method. The results show that the steel slag microparticles significantly affected the reduction in P retention and increased pH in Andisols. The best dose for increasing the pH is 7%. Steel slag with a size of 1.7 µm is able to increase the pH from 4.53 to 7.99 after a two-month incubation.PENGARUH PARTIKEL MIKRO TERAK BAJA TERHADAP RETENSI P DAN PH PADA ANDISOLPenelitian ini bertujuan untuk mengetahui pengaruh pemberian partikel mikro terak baja terhadap retensi P, kemasaman tanah pada Andisol asal Ciater, Jawa Barat. Penelitian telah dilaksanakan pada bulan November 2017 sampai dengan Januari 2018. Andisol berasal dari Perkebunan Teh PTPN XIII-Ciater, Kabupaten Subang, sedangkan terak baja diperoleh dari PT. Krakatau Steel Indonesia. Rancangan penelitian yang digunakan adalah Rancangan Acak Lengkap yang terdiri dari 11 perlakuan dan 3 ulangan, sehingga total seluruh perlakuan adalah 33 polibeg percobaan. Perlakuan yang diberikan yaitu kontrol, terak baja ukuran 500 mesh dan terak baja ukuran 1,7 µm. Media inkubasi disimpan di Laboratorium Fisika Tanah Fakultas Pertanian UNPAD dan diinkubasikan selama 2 bulan.Parameter yang diamati adalah Retensi P dianalisis dengan metode Blakemore, dan pH tanah dianalisis dengan metode elektrometri.Hasil penelitian menunjukkan bahwa pemberian partikel mikro terak baja berpengaruh nyata terhadap penurunan retensi P dan peningkatan pH pada Andisol asal Ciater, Jawa Barat. Sedangkan dosis terbaik dalam meningkatkan pH yakni 7% terak baja dengan ukuran 1,7 µm mampu meningkatkan pH dari 4,53 menjadi 7,99 setelah dua bulan inkubasi.
INTELLECTUAL CAPITAL AND FINANCIAL PERFORMANCE OF THE COMPANY
Authors: Maharani Nila Bilqis , Faisal Faisal 
Published: February 2020

This study tests the relationship between intellectual capital and corporate financial performance of Indonesian companies. 63 companies of six industrial sectors listed on Bloomberg Database in 2015-2017 were selected as a sample. The descriptive statistics, Spearman’s correlation and non-parametric Kruskall-Wallisand Mann-Whitneytests were used to analyze the relationship between dependent (financial performance) and independent (intellectual capital) variables. Our findings show that intellectual capital provides a positive contribution effect on corporate financial performance. Consistent with resource- based theory, this finding suggests that intellectual capital is a strategic resource that can generate a value for company to gain a superior performance and competitive advantage.
CAREER SELECTION OF PROFESSIONAL PUBLIC ACCOUNTANTS WITH EXPECTANCY THEORY
Authors: Januarti Indira , Chariri Anis 
Published: February 2020

Abstract This study aims to provide empirical evidence of the influence of intrinsic motivation (social values) and extrinsic (financial, professional training, work environment) selection of a career as a public accountant and non-CPAs. Similar research has been done but the respondent students majoring in accounting, so that the election is still a career intentions. This study uses respondents who had actually obtained the register of accountants so that their career choice becomes real not just intentions. The study sample as many as 251 graduates PPA Undip. Data obtained by sending a questionnaire via e-mail or via courier. The analytical tool used to test the hypothesis is logistic regression.The results of the study provide evidence that the only variable professional training has positive effects on the possibility of selecting a career as a public accountant and non-CPAs. Variable values of social, financial and environmental work is not a positive influence on elections for a career as a public accountant and non-CPAs. Financial variables and the working environment has a negative value, ie non public accounting profession provide financial expectations and working environment a better than the public accounting profession
Islamic Banking Strategies In Rural Area: Developing Halal Tourism and Enhancing The Local Welfare
Authors: Ameraldo Fedi , Saiful Saiful , Husaini Husaini 
Published: February 2020

ABSTRACTThe purpose of this study is to analyze the potential contribution of Islamic banking to development of Halal tourism and the enhancement of local community welfare in rural area.The present study employs a critical analytic approach based on extensive review and discussing the possible contribution of Islamic banking to development of Halal tourism and the local communities in rural area.As discussed in the paper there are some strategies for Islamic banking in the rural area. First, Islamic banking can establish special purpose vehicle to run the microfinance scheme in the rural area in order to minimize the potential risks. Second, some financing mechanisms also can be run by the Islamic banks both sources from internal and external resources, such as participatory model – musyarakah and mudharabah and third parties fund – zakah, infaq, sadaqah and waqf.Last, the branchless banking strategy is also proposed but with a certain intermediations should be firstly done by the Islamic banks, such as social and financial intermediation. Keywords Indonesia, Islamic Banking, Halal tourism, Local Welfare