bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and predictors of work related musculoskeletal disorders among workers of a Gold mine in the Democratic Republic of Congo
Authors: Okello Alfred , Wafula Solomon Tsebeni , Deogratias Deogratias K , Mugambe Richard K 
Published: November 2020

Abstract
Background: Work-related musculoskeletal disorders (WRMSDs) are a major constraint to worker performance and health. However, research on their prevalence and associated factors among workers at gold mines in the Democratic Republic of Congo (DRC) is insufficient. The present study aimed to determine the prevalence and predictors of WRMSDs among workers of a Gold Mine in South Kivu, DRC. Methods: Cross sectional data on prevalence of WRMSDs and risk factors was collected using a modified Nordic questionnaire and upper limb Core QX checklist from 196 workers of a gold mine. WRMSDs were defined as pain or injury(ies) or discomfort, numbness or limitation of movement in the musculoskeletal system at any time in the past 12 months which lasted at least 24hours. These had to be either induced or aggravated by work and circumstances of its performance. A generalised linear model of the Poison family with link log and robust error variances was used to generate prevalence ratios (PRs) and 95% confidence intervals (CIs) for the factors associated with WRMSDs. The effect of individual, ergonomic and psychosocial factors on WRMSDs were investigated while controlling for known confounders. Results: Most workers were males 187 (95.4%) and their age ranged between 23 and 60 years with mean of 36.3 years. Of the 196 workers, 49 (25.0%) reported having at least one WRMSD during the previous 12 months. WRMSDs with highest occurrence rate were the lower back pain (14.8%), followed by thighs/hip pain (9.2%) and shoulder pain (8.2%). Prolonged heavy lifting/shovelling shovelling (PR = 1.69, 95% CI [1.32, 3.24] and longer work shifts (> 9hrs) (PR = 3.56, 95% CI [1.76, 16.58]) were predictive for WRMSDs while jobs with low demands were protective against WRMSDs (PR = 0.18, 95% CI [0.08, 0.44]).Conclusion: The prevalence of WRMSDs is high and associated with prolonged heavy lifting/shovelling, longer work shifts and job demands. We recommend lowering workload and job demands and improving work ergonomics to mitigate and prevent the WRMSDs among workers in goldmines.
Genome-Wide in Silico Analysis of Ethylene Responsive Factors Associated with Stress Responses in Wheat
Authors: Aamer Hareem , Gul Alvina , Amir Rabia , Hayat Muhammad Qasim , Munir Faiza , Bakhtiar Syeda Marriam , Babar Mustafeez , Khalid Zoya 
Published: November 2020

Abstract
Background: Transcription factors have largely been involved in the qualitative and quantitative regulation of gene expression. Among the diverse transcription factor families, AP2 (Apetala2) /ERF (Ethylene responsive factors superfamily is a well-known plant family of proteins for controlling various and diverse stress responses in plants. Ethylene responsive factors (ERF) are known to be vital for generating various stress responses.Results: A total of 181 TaERF proteins were identified in Triticum aestivum. Phylogenetic analysis, conserved motif analysis, chromosomal localization, gene structure analysis and multiple sequence alignment of ERF genes along with protein- protein interaction network analysis was performed. The phylogenetic analysis led to classification of these ERF members into 10 major groups and provided evolutionary relationship among the groups on the basis of similar protein motifs like which include WLG and 15 others. Further analysis revealed exon number, molecular weight, isoelectric point, and length of proteins. Gene ontology analysis concluded that TaERF were involved in responses to many Stressors, revealing their possible function. Sub cellular localization revealed that most of the proteins were confined to nucleus, cytoplasm and mitochondria. Network analysis provided insight of proteins involved in generating responses to stresses based on topological analysis and betweeness centrality of the network based on network theory.Conclusions: Genome-wide identification, gene structure, phylogeny and network analysis of TaERF proteins in Triticum aestivum supplied a solid theoretical foundation for the functional study of TaERF family. The bioinformatics analyses of 181 TaERF were implemented systematically revealing proteins characteristics and structural information.
Cross-cultural information for Japanese nurses at an international hospital: a controlled before-after intervention study
Authors: Nishikawa Mariko , Yamanaka Masaaki , Shibanuma Akira , Kiriya Junko , Jimba Masamine 
Published: November 2020

Abstract
BackgroundOverseas visitors to Japan steadily increased for a decade until the pandemic of 2020. In 2019, 31.8 million people visited the country due to an easing of restrictions and an emphasis on tourism. Nurses are the forefront of the healthcare system when they interact with those overseas visitors at a clinic or hospital. The goal of this study is to evaluate the efficacy of providing health information, through an ordinary travel guidebook or a short digital cartoon by measuring the anxiety level of Japanese nurses who deal with foreign patients.MethodOur approach involves a controlled before-after intervention study from January to March in 2016 at a major international hospital in Japan. We surveyed nurses at three wards of the hospital who understood English and cared for foreign patients as the 1st intervention group. Following which, we collected data from the same 1st intervention group, but now considered as the 2nd intervention group. Nurses in the 1st intervention group read health information in a travel guidebook for Japan. Nurses in the 2nd intervention read health information in the guidebook and watched a four-minute digital cartoon in English on health services in Japan, titled Mari Info. After each intervention, the nurses answered a self-questionnaire, wherein we assessed their level of anxiety to care for foreign patients. We evaluated the results through statistical testing and the State-Trait Anxiety Inventory Form Y (STAI-Y).ResultsOf 111 nurses, 83 (74.8%) completed both interventions and a questionnaire. Reading the guidebook as well as watching a digital cartoon, as the 2nd intervention was more effective in reducing the level of anxiety to care for foreign patients compared to reading only the guidebook.ConclusionsJapanese nurses can lower their anxieties on dealing with foreign patients by knowing the various forms of healthcare information currently accessible to overseas visitors in both guidebooks and digital content. This helps them learn the ethical concerns and cultural norms of foreign patients they might care for.
Chemical Profiling of Chlorophytum comosum (Thunb.) Jaques by GC-MS/LC-ESIMS and its Antiproliferative Effects on Human Carcinoma Cell Lines
Authors: Adhami Shehla , Farooqi Humaira , Abdin Malik Z. , Prasad Ram , Malik Asrar A. 
Published: November 2020

Background:
Chlorophytum comosum, popularly known as Spider Ivy, is used as a medicinal plant in
traditional Chinese medicine, however, its detailed chemical composition and biological activity are yet
unexplored.

Objective:
To carry out the phytochemical investigation on different parts of Chlorophytum comosum using GCMS/
LC-ESI-MS and evaluation of its antioxidant, hemolytic and antiproliferative potential on breast cancer
(MCF-7), lung cancer (A549, H1299) and normal lung (L-132) cell lines.

Methods:
Chemical constituents from aqueous roots and leaves extracts were identified using LC-ESI-MS/GCMS.
The identified compounds were annotated based on the match of mass spectra with the literature using NIST
14 and METLIN databases. Antioxidant activity was studied using DPPH, FRAP and TPC assays. The
antiproliferative effects of ethanolic roots and leaves extracts of Chlorophytum comosum were measured by MTT
assay on breast cancer (MCF-7), lung cancer (A549 & H1299) and normal lung (L-132) cell lines. The toxicity
studies of the extracts were carried out using Hemolysis assay.

Results:
GC-MS analysis identified 34 metabolites in roots and 17 from leaves, while 17 compounds from roots
and 7 from leaves were detected by LC-ESI-MS. Significant antiproliferative effects were observed on the A549
and MCF-7 cancer cell lines with IC50 values ranging from 56.86 μg/ml to 68.68 μg/ml while no marked
response was observed against normal cell line L-132.

Conclusion:
Our study represents the first report on the detailed chemical composition and antiproliferative
potential of Chlorophytum comosum against lung and breast cancer cell lines.
Phyto-synthesized Gold Nanoparticles as Antitumor Agents
Authors: Teodor Eugenia Dumitra , Radu Gabriel Lucian 
Published: November 2020

Background::
Phyto, or plant-derived metal nanoparticles, are an interesting and intensive
studied group of green synthesized nanoparticles. In the last decade, numerous medicinal plant
extracts were used for the synthesis of stable gold or silver nanoparticles with diverse biological effects,
such as antioxidant activity, antimicrobial activity, anti-inflammatory activity, hypoglycemic
effect, antitumor activity and catalytic activity.

Results::
This review has systematized and discussed information from the last 5 years about the research
regarding antitumor/anticancer potential of gold nanoparticles obtained via medicinal plant
extracts, with special attention on their selective cytotoxicity on tumor cells and on their mechanism
of action, in vitro and in vivo assessments.

Conclusion::
Much more in vivo and clinical studies are needed before considering phyto-synthesized
gold nanoparticles as significant for future medicine.
The Emergence of Novel Coronavirus Disease, Global Treatment Update and its Containment Strategies in Overpopulated Countries: A Review
Authors: Azim Fazli , Islam Md Shahidul , Saju Hedaeytullah , Fatema Kaniz , Hayat Aneela , Kamal Mostofa , Sarfraz Md , Muhammad Nawshad , Rizvi Syed A.A. 
Published: November 2020

:
The ongoing pandemic of the novel coronavirus SARS-CoV-2 (COVID-19) has created
a major challenge for the public health worldwide. The reported cases indicate that the outbreak is
more widespread than initially assumed. Around 18 million people have been infected with
689,000 reported deaths (August 2020; the number is increasing daily); with a high mutation rate,
this virus poses an even more serious threat worldwide. The actual source of COVID-19 is still unclear;
even if the initial reports link it to the Chinese seafood wet market in Wuhan, other animals
such as birds, snakes, and many small mammals including bats are also linked with this novel coronavirus.
The structure of the COVID-19 shows distinctive proteins among which spike proteins
have a pivotal role in host cell attachment and virus-cell membrane fusion in order to facilitate
virus infection. Currently, no specific antiviral treatment or vaccine is available. Various drug candidates,
including SARS-CoV and MERS-CoV protease inhibitors, neuraminidase inhibitors, RNA
synthesis inhibitors, ACE2 inhibitors and lungs supportive therapy, are under trials. Cell-based therapy
also appeared with remarkable treatment possibilities. In this article, we endeavored to
succinctly cover the current and available treatment options, including pharmaceuticals, cell-based
therapy, and traditional medicine. We also focused on the extent of damages by this novel coronavirus
in India, Pakistan, and Bangladesh; the strategies adopted and the research activities initiated
so far by these densely populated countries (neighboring China) are explained in this review.
COVID-19: A Daily Dose of Yoga to Cope with Anxiety
Authors: Gautam Surabhi , Dada Rima 
Published: November 2020

:
The coronavirus disease (COVID-19) pandemic has undoubtedly created unbearable psychological
pressure on our minds such as anxiety, fear, worry, changing sleep patterns, changing
eating patterns, worsening of existing chronic or mental health conditions, etc. There is an urgent
need for the adoption of an effective coping strategy. We propose that yoga-based intervention
may aid in improving mental and physical health with its multi-faceted dimensions.
Association of Mobile Instant Messaging Chat Group Participation With Family Functioning and Well-Being: Population-Based Cross-sectional Study
Authors: Zhao Sheng Zhi , Luk Tzu Tsun , Guo Ningyuan , Wang Man Ping , Lai Agnes Yuen Kwan , Wong Bonny Yee Man , Fong Daniel Yee Tak , Chan Sophia Siu Chee , Lam Tai Hing 
Published: November 2020

Background
Convenient and quality family communication improves family functioning and well-being. Using mobile instant messaging (IM) for family communication is increasingly popular, but its association with family functioning and family well-being has not been reported.

Objective
The aim of this study was to examine the association of the use of family IM chat groups with family functioning and well-being, and the mediating effect of family communication quality among Chinese adults in Hong Kong.

Methods
We analyzed data from the Family and Health Information Trend Survey (FHInTS), a territory-wide, probability-based telephone survey conducted in 2017. The quality of family communication, family functioning, and well-being was assessed using the Family Communication Scale; Family Adaptation, Partnership, Growth, Affection, and Resolve (APGAR) Scale; and Family Well-Being Scale (family heath, harmony, and happiness), respectively. Respondents also reported the number of family IM chat groups (0, 1, 2, ≥3), and numbers of IM messages received (<1, 1-2, 3-10, 11-20, >20) and sent (<1, 1-2, 3-10, 11-20, >20) daily. The frequency of family IM chat interaction (range 0-8) was calculated by combining the number of messages received from and sent to the family IM chat groups daily. Covariates included sociodemographic characteristics and the frequency of family face-to-face communication (often, sometimes, seldom, or never). Data were weighted by sex, age, and education of the general population. Adjusted β coefficients of family functioning and well-being in relation to having a family IM chat group, and numbers of messages received and sent were calculated. The mediation effects of family communication on these associations were assessed, controlling for the covariates.

Results
A random sample of 1638 Chinese adults (45.6% men; 78.1% aged 25 to 64 years) were interviewed (response rate: 74.4%). Female, younger age, being married or cohabiting, higher education, higher income, better family functioning, and well-being were associated with having at least one family IM chat group (all P<.01). Higher scores of family communication, family APGAR, and family well-being were associated with having more family IM chat groups and more messages received from and sent to family IM chat groups daily (all P for trend <.01). More frequent family IM chat interaction was associated with higher scores of family communication, family APGAR, and family well-being (β=.16-.83, all P for trend <.001). The associations of family IM chat interaction with family functioning and well-being were moderately (51.0%-59.6%) mediated by family communication.

Conclusions
Use of a family IM chat group was associated with higher family functioning and well-being, and the association was partially mediated by family communication.
Desarrollo de un soldador por puntos para el laboratorio de proceso de manufactura de la Universidad Francisco de Paula Santander Ocaña
Authors: Flórez-Solano Eder Norberto , Espinel-Blanco Edwin Edgardo , Barbosa-Jaimes Jhon Erickson 
Published: November 2020

La soldadura por puntos es la forma que más se aplica entre la soldadura por resistencia. Esta consiste en prensar dos piezas de metal laminado entre dos electrodos de cobre, por donde pasa una corriente eléctrica con suficiente intensidad por las piezas, para dar lugar a la unión de las piezas. La soldadura por puntos pertenece al grupo de soldadura por resistencia en los cuales se genera el calor necesario para soldar, por la resistencia de las partes al paso de una corriente eléctrica. Al utilizar la presión adicional se mejora las propiedades mecánicas de la pieza. Este tipo de soldadura es el más utilizado para la unión de láminas de acero de espesores pequeños o medianos, debido a sus buenas características, localización y rapidez. En laboratorios como en los programas de ingeniería mecánica, existe una deficiencia para obtener todos los equipos, especialmente los equipos de soldadura, por su variedad de tipos de procesos, es por esta razón que este proyecto logró la construcción de un soldador por puntos, a partir de elementos ya existentes, para profundizar los procesos de soldadura en el contenido de la asignatura de forma práctica y en la investigación de estos temas específicos.
Engineering Gology Model of Bener Dam Diversion Tunnels in Geological Risk Disaster Mitigation
Authors: Sasangka Daru Jaka , Insani Dian , Indrawan I Gde Budi 
Published: November 2020

The Bener Dam Diversion Tunnel Plan is located in Bener District, Purworejo Regency. Engineering geology mapping data, drillimg data and laboratory data used as primary data. Surface and subsurface analysis show that each rock unit has different index and mechanical properties. Generally, the rock mass quality conditions in the dam belonged to good Rock (80%) in the Rock Mass Rating (RMR) system (Bieniawski, 1989). The other rock mass quality type also found among them fair rock (5%), poor rock (5%), and very poor rock (10%). Poor rock mass quality conditions were controlled by geological structures, especially faults that partially cut through the tunnel geometry. The very poor quality of rock mass was in the volcanic lens (loose sand material) did not cut through the tunnel path. The difference stand-up time of the rock on the tunnel requires proper mitigation (Nguyen Nguyen, 2015). The stand-up time belonged to the dangerous condition was in the fault zone with poor rock mass quality, while the lens with very bad rock mass quality did not affect the stability of the excavation of the tunnel.
PENGARUH BEBAN OPERASIONAL PENDAPATAN OPERASIONAL (BOPO), NON PERFORMING FINANCING, DAN UKURAN PERUSAHAAN TERHADAP TINGKAT EFISIENSI PERBANKAN SYARIAH DI INDONESIA
Authors: Fauzi Rizka , Daud Rulfah M 
Published: November 2020

This research aims to investigate the influence of BOPO, Non Performing Financing, and Firm Size on Efficiency Level of Islamic Banking in Indonesia. The efficiency score is obtained using Data Envelopment Analysis (DEA) Method. The type of data employed is secondary data from financial statements of each banks between 2014 and 2018. The results of this research indicate that (1) Operating Expenses against Operating Income, Non Performing Financing, and Firm Size simultaneously affect the efficiency level, (2) Operating Expenses against Operating Income does not affect the efficiency level, (3) Non Performing Financing does not affect the efficiency level, and (4) Firm Size affects the efficiency level of islamic banking in Indonesia
The Arctic Five: search for a balance of power in the region
Authors: Doroshenko I. S. 
Published: November 2020

Due to climate change, the Arctic region becomes a place of geopolitical rivalry of both Arctic and non-Arctic states. Traditional formats for determining the agenda in the region are effective, but with the advent of the interest of an increasing number of international actors, these formats are transforming, which may affect the balance of power in the region. The growing activity of Asian countries in the Arctic, primarily China, is forcing regional states to make adjustments to the development strategy of the region. The rapid renewal of its potential in the northern territories of Russia caused a negative reaction from the western countries, especially after 2014.Such aspirations have emerged as the internationalization of the region by Northern Europe and China, the desire to draw clear boundaries on the part of Russia and Canada, and the buildup of US influence on its colleagues in the North Atlantic bloc. This situation may cause an uncontrolled increase in tension in the region, especially if new alliances between the Arctic and non-Arctic countries are created. The author considers the current approaches of the countries of the Arctic five, analyzes the true motives of internationalization and the role of the format of the Arctic five in maintaining a balance of power and stability in the northern latitudes.
LAND CREATIONS AND FARMING SYSTEM TO INCREASE OF RICE PRODUCTIVITY AND FARMER’S INCOME (CASE STUDY IN BATANG TAMPO IRRIGATION SYSTEM - LINTAU BUO)
Authors: Asmuti Ayendra , Tjandra Agita 
Published: November 2020

It is estimated that around 95 percent of national rice production is supplied from paddy fields, so the paddy fields is very strategic in national food securities. Therefore, the potential carrying capacity and productivity of rice fields must be maintained and developed. But on the contrary the productivity of paddy fields in Sub Das Tampo, Lintau Buo Utara, Tanah Datar District, West Sumatra, there is an indication of a decrease in paddy productivity in the last 10 years (Agita and Ayendra 2018). Decreased paddy productivity is indicated as a result of 1.) Drainage or nutrient deficit due to harvest carried out more than what is given through fertilization or addition of nutrients from irrigation water, 2). Excess or lack of certain nutrients due to unbalanced fertilization, 3). Decreased of soil organic content in the land and 4). Decrease in the quality of rice field management, especially: a). the use of inorganic fertilizers which causes low organic matter content and soil texture becomes porous quench, so it is less able to hold water, b). use of rotary plow in tillage for a long time which causes the processing layer and the depth of the root zone to become shallower ( into 10-15 cm), c). less intense of crop maintenance. This research was carried out by creating of soil tillage from 10-15 cm to 20-25 cm using a plow and increasing of organic matter by adding manure of 50 tons / ha (5% soil tillage zone ) to the rice fields in the Farmers Group of Tanjung Mutiara in Tampo Irrigation System, Nagari Lubuk Jantan , Kecamatan Lintau Buo Utara. The results of the study showed an increase in land productivity from an average of 3.2 tons / ha to 4.6 tons / ha and increase farmers' income by Rp 1.200.000 / ha.Key words : land creation, soil tillage, productivity