bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resúmenes de literatura nacional
Authors: De Obstetricia y Ginecología Federación Colombiana 
Published: June 2020

Sacrocolpopexia modificada Henry Ortiz, Guillermo Castro y Uriel AceroUtilidad de pirazanone en procesos inflamatorios gineco-obstetricos Carlos Villamizar Toxoplasmosis prenatal Jaime Romero, Roberto Vergara, Alvaro Quiroga, Enrique Gutiérrez, Dora Ramírez, Juan Guillermo Uribe, Nohora Rodríguez y Max Grohl Resúmenes de literatura mundial colaboración del programa informe -OFA, Bogotá- Biopsia de cono - un tratamiento sin hospitalización Berkus M., Daly J. W. Tratamiento de neoplasia intraepitelial cervical mediante biopsia de cono Jones H. W. Buller R. Decesos en el pabellón de ginecología del hospital Groote Schuur, Cape Town, 1957 – 1977 Van Geverden Embarazo y parto después de la conización de la cerviz Onroos M. Lesiones precancerosas de la cerviz Lansac J.
Aborto inducido
Authors: Villamizar Flórez Hernando 
Published: June 2020

El autor hace resumen de la legislación mundial sobre aborto particularizando sobre la que actualmente rige en Colombia. Argumenta el pro y el contra y después de consideraciones filosóficas varias, pregunta si LA LEGALIZACION DEL ABORTO SERIA (en Colombia) UN PROGRESO O UN RETROCESO. Plantea el tema del ABORTO TERAPEUTICO como solución final y única para conservar la vida o la salud física o mental de la madre, mencionando el aborto por indicación eugenésica en caso de graves taras hereditarias. Por último descarta el aborto como parte del programa de Planificación Familiar en Colombia.
Sección Informativa
Authors: De Obstetricia y Ginecología Federacion Colombiana 
Published: June 2020

Congreso internacional de Endoscopia Ginecología y Microcirugia.Congreso interncional de Senología.X. Congreso mundial de Ginecología y Obstetricia.Curso de Pos-grado de Citopatología.Sociedad Colombiana de Sexologia.
PEMBEBANAN JAMINAN ATAS BENDA BENDA TIDAK BERGERAK DALAM KONTRAK PEMBIAYAAN MUDHARABAHPERSPEKTIF UNDANG-UNDANG NOMOR 4 TAHUN 1996 TENTANG HAK TANGGUNGAN
Authors: Harahap Muhammad Yadi 
Published: June 2020

<p>The imposition of collateral for immovable objects, especially land in mudharabah financing contracts, is preceded by making a guarantee contract to the capital owners. The purpose is to fulfil the implementation of obligation payment, even though there must not be collateral in mudharabah financing contract. Therefore, the guarantee of liability means that the collateral at any time can be confiscated and sold by the capital owner to repay the obligation. This study aims to find a comprehensive solution about how and what is the purpose of imposing collateral for immovable objects which are originally not part of mudharabah financing contracts principles. Empirical juridical research method is employed where law is not only considered as law in books but also in action with legal regulation approach, namely the 1996 Law Number 4 concerning Mortgage Rights. The results indicate that the collateral imposition for immovable objects in mudharabah financing contract refers to the aforementioned law concerning mortgage rights which aims at applying the precautionary and risk principles based on the 2008 Law Number 21 concerning Sharia Banking.</p><p>Pembebanan jaminan atas benda-benda tidak bergerak khususnya tanah dalam kontrak pembiayaan mudharabahlebih dahulu dilakukan kontrak pemberian jaminan kepada pemilik modal dengan tujuan untuk pemenuhanpelaksanaan pembayaran kewajiban, sekalipun pada prinsipnya dalam kontrak pembiayaan mudharabah tidak dibenarkan ada jaminan.Untuk itu pembebanan jaminan hak tanggungan dengan sendirinya telah meletakkan kebendaannya di mana setiap saat dapat disita dan dijual oleh pemilik modal untuk mengembalikan pelunasan kewajiban dalam kontrak pembiayaan mudharabah.Penelitian ini bertujuan untuk mencari solusi secara komprehensif tentang bagaimana dan apa tujuan dilakukan pembebanan jaminan atas benda tidak bergerak dalam kontrak pembiayaan mudharabahyang pada prinsipnya tidak dibenarkan. Untuk menjawab pertanyaan penelitian tersebut metode yang digunakan adalah metode penelitian yuridis empiris di mana hukum tidak hanya dilihat sebagai law in books tetapi juga law in action dengan pendekatan peraturan perundang-undangan yaitu UU No. 4 Tahun 1996 Tentang Hak Tanggungan. Hasil penelitian menunjukkan bahwa pembebanan jaminan atas benda-benda tidak bergerak dalam kontrak pembiayaan mudharabah mengacu kepada UU No. 4 Tahun 1996 tentang hak tanggungan, dengan tujuan untuk menerapkan prinsip kehati-hatian dan prinsip risiko sesuai dengan amanat Undang-undang No. 21 Tahun 2008 Tentang Perbankan Syariah.</p>
KEABSAHAN AKTA RISALAH LELANG SEBAGAI AKTA OTENTIK DALAM PELAKSANAAN LELANG ELEKTRONIK OLEH KANTOR PELAYANAN KEKAYAAN NEGARA DAN LELANG
Authors: KARINA AHNIA SEPTYA , Sukarmi Sukarmi , Kawuryan Endang Sri 
Published: June 2020

<p>Currently, auction can be done through internet media a.k.a. e-auction. E-auction sells the goods by offering written prices without the presence of participants conducted through an internet-based auction application. This internet-based auction is similar with conventional one. The difference is in case of face-to-face which will affect the originality of Auction Treatise. Treatise is the official report of auction issued by Auction Officer. This paper aims at analyzing the validity of treatise as an authentic document in e-auction. This is a normative juridical writing by analyzing the validity of e-auction treatise reviewed with legislation related to internet-based auction. The results indicate that the treatise in e-auction is authentic since it follows the principles written in Article 1868 of the Civil Code. However, in PMK Number 90/PMK.06/2016 and Vendu Reglement concerning the recitation of the chief of Auction Treatise can be done using Lex Specialis Derogat Legi Generalis principles. The e-auction treatise also has valid proof as long as there is no lawsuit filing.</p><p>Saat ini, lelang dapat dilakukan melalui media internet atau e-auction. E-auction adalah penjualan barang dengan penawaran harga secara tertulis tanpa kehadiran peserta lelang yang dilakukan melalui aplikasi lelang berbasis internet. Lelang berbasis internet ini sama seperti pelaksanaan lelang konvensional. Perbedaanya terletak dalam hal tatap muka yang nantinya akan berpengaruh terhadap keotentikan Risalah Lelang. Risalah Lelang adalah berita acara<br />pelaksanaan lelang yang dibuat oleh Pejabat Lelang. Makalah ini mеngаnаlіsis kеаbsаhаn аktа Rіsаlаh Lеlаng sеbаgаі аktа оtеntіk dаlаm pеlаksаnааn lеlаng еlеktrоnіk. Penulisan ini adalah yuridis normatif dengan menganalisis keabsahan Risalah Lelnag elektronik yang dikaji dengan peraturan perundang-undangan yang berkaitan dengan lelang melalui internet. Hasil menunjukkan bahwa Risalah Lelang dalam lelang internet merupakan akta otentik karena telah memenuhi unsur-unsur dalam Pasal 1868 KUH Perdata. Namun dalam PMK Nomor 90/PMK.06/2016 dan Vendu Reglement tentang pembacaan Kepala Risalah Lelang tersebut dapat terselesaikan dengan asas Lex Specialis Derogat Legi Generalis. Risalah Lelang dalam lelang melalui media internet juga memiliki kekuatan pembuktian sempurna sepanjang tidak ada yang melakukan gugatan.</p>
Refeeding Postmolting Method to Improve Weekly Production Performance of Rejected Laying Hens with Low Mortality
Authors: Airin Claude Mona , Hana Amelia , Astuti Pudji , Sarmin Sarmin , Susmiati Trini , Herawati Okti 
Published: June 2020

This research aimed to investigate the influence of gradually feeding rejected laying hens after molting on the performance of production. This research used 6,000 rejected laying hens of 80 weeks old in Subur Farm. Molting method was a modification method by reducing the feed gradually. At the beginning of this research, the feed was given 120 g/laying hens/day and it would be reduced by 10 g/laying hens/day until it reach 50 g/laying hens/day. In the next phase, all chickens fasted for seven days then the chicken was given 10 g/laying hens on the first day. The feed was increased 10 g/laying hens every two days up to 120 g/laying hens/day. Data Collection of Feed conversion ratio (FCR), mortality rate, amount of feed, and egg production were taken at the start of re-feeding. The results showed that during the period of molting until refeeding, mortality was 3.6%, an increase in egg production was seen since week 1, peak of production was 78% at week 9 with FCR 2.3. The results of statistical analysis showed significant differences (P<0.05) on the percentage of egg production between time periods after the treatment of feed reduction. As the conclusion, molting followed by refeeding in rejected laying hen influences weekly production performance by extending peak production period, optimal FCR and daily egg production.
Aids in physics: Design and development
Authors: Hasim Norfaridatul Akmar Bt , Karim Mohd Mustamam Bin Abd , Rahman Nurulhuda Binti Abd 
Published: June 2020

Electricity is found to be a difficult topic to learn due to its abstract concepts. Research showed that games based learning using dioramas can help students to interest and enhance students’ understanding in learning abstract Physics topics. As a result, PhyKER Games was developed in order to assist students in the learning of the Electricity circuit topic. ADDIE model (analysis, design, development, implementation and evaluation) as instructional design and develope of PhyKER Games. Dioramas were added in PhyKER Games to depict real scenes. The information delivery and the flow of content follow the ADDIE phases theory. It is hoped that the PhyKER Games would be able to assist students in the learning of Electricity circuit terms of concept understanding and motivation level.
Mortality Analysis of the Pulmonary Department of the Emergency Hospital
Authors: Dubrovskaya I. I. , Puzyreva L. V. , Yanina O. A. , Didenko N. E. , Druzenko A. V. , Lobastov A. Yu. 
Published: June 2020

The assessment of mortality in medical institutions is a reflection of the health status of the majority of the population and the assessment of preventive measures aimed at reducing the incidence of certain nosologies.Purpose of the study: to assess mortality in the pulmonology department of the emergency hospital on-duty.Materials and methods. The reporting data of the pulmonology department for the period from 2017 to 2019 were used. using statistical research methods.Results. Pneumonia led to death in 35,2% of patients, which was associated with hospitalization of elderly and senile patients with a severe comorbid background, as well as the admission of patients leading an asocial lifestyle, late seeking medical help. Mortality from HIV infection caused death in 11,5% of patients, all in the late stages of infection 4B with the development of secondary diseases (bacterial pneumonia, pulmonary tuberculosis, pneumocystis pneumonia). Mortality from malignant neoplasms remains high during the study period, which indicates a late diagnosis. During the study period, oncology caused death in 13,2% of patients.Conclusion. High mortality in the pulmonology department is due to late verification of pneumonia, HIV infection and malignant neoplasms.
Percutaneous-perventricular device closure of ventricular septal defect: mid-term follow-up.
Authors: Wang Long , Xie Lin , Ruan Weiqiang , Li Tao , Gan Changping , Lin Ke 
Published: June 2020

Abstract
Background: This report presents updated data and mid-term follow-up information to a former study introducing the novel technique of percutaneous-perventricular device closure of doubly committed subarterial ventricular septal defect. Methods: Thirty-eight patients were added to the former series. There were 54 patients in total who had isolated doubly committed subarterial ventricular septal defects and underwent percutaneous-perventricular device closure. Closure outcomes and possible complications were measured in the hospital and during the 2.5-year follow-up. Results: Surgery was successful in 53 patients (98.1%). There was no death, residual shunt, new valve regurgitation or arrhythmia either perioperatively or during the entire follow-up period. Only one patient developed pericardial effusion and tamponade in the former series. The mean hospital stay was 3.2±0.6 days (range, 3.0 to 6.0 days), and only one unsuccessful case needed blood transfusion (1.9%). Conclusions: The percutaneous-perventricular device closure of isolated doubly committed subarterial ventricular septal defects appeared to be safe. Close monitoring for bleeding is essential postoperatively, especially in younger patients. This technique is generally safe with acceptable mid-term follow-up.
The DLC-1 tumor suppressor is involved in regulating immunomodulation of human mesenchymal stem cells through interacting with the Notch1 protein
Authors: Na Tao , Zhang Kehua , Yuan Bao-Zhu 
Published: June 2020

Abstract
Background Immunomodulatory activities of human mesenchymal stem cells (hMSCs) has been widely recognized as the most critical function of hMSCs for exerting its therapeutic effects. However, the detailed mechanisms responsible for regulating the immunomodulation of hMSCs still remain largely unknown. Previous studies revealed that the Notch1 protein exerted a pro-immunomodulatory function probably through interacting with the protein(s) subjective to proteasome-mediated protein degradation. The DLC-1 protein represents a well characterized tumor suppressor subjective to proteasome-mediated degradation. However, the detailed signaling pathway of Notch1 and the involvement of DLC-1 in regulating the immunomodulation of hMSCs have not been studied before. Methods The transfection with cDNA or siRNA into hMSCs assisted by co-culture of hMSCs with peripheral blood mononuclear cells and small molecule inhibitors of signaling proteins, followed by immunoprecipitation, Western blotting, RT-PCR, and flowcytometry, were employed to characterize the Notch1 signaling, to identify DLC-1 as a candidate proteasome-targeted protein, and to characterize DLC-1 signaling pathway and its interaction with the Notch1 signaling, in the regulation of immunomodulation of hMSCs, specifically, the inhibition of pro-inflammatory CD4+-Th1 lymphocytes, and the release of immunomodulatory molecule IDO1. Statistical analysis One-way ANOVA was utilized as a statistical tool to analyze the data presented as means ± SEM of at least three separate experiments. Results The present study revealed that the Notch1-Hey1 axis, but not the Notch1-Hes1 axis, was likely responsible for mediating the pro-immunomodulatory function of the Notch1 signaling. The DLC-1 protein was found subjective to proteasome-mediated protein degradation mediated by the DDB1 and FBXW5 E3 ligases and served as an inhibitor of the immunomodulation of hMSCs through inhibiting Rock1, but not Rock2, downstream the DLC-1 signaling. The Notch1 signaling in the Notch1-Hey1 pathway and the DLC-1 signaling in the DLC-1-Rock1-FBXW5 pathway exhibited a mutual exclusion interaction in the regulation of immunomodulation of hMSCs. Conclusions The present study uncovers a novel function of DLC-1 tumor suppressor in regulating the immunomodulation of hMSCs. It also proposes a novel mutual exclusion mechanism between the DLC-1 signaling and the Notch1 signaling that is possibly responsible for fine-tuning the immunomodulation of hMSCs with different clinical implications in hMSCs therapy.
Communication of advance care planning decisions: a retrospective cohort study of documents in general practice
Authors: Panozzo Laura , Harvey Pam , Adams Meagan-Jane , O'Connor Dennis , Ward Bernadette 
Published: June 2020

Abstract
Background Doctors, particularly general practitioners, play a significant role in assisting patients to create advance care plans. When medically indicated, these documents are important tools to promote congruence between end-of-life care and patient’s personal preferences. Despite this, little is known regarding the availability of these documents in hospitals. The aim of this study was to identify the proportion of people who died in hospital without an advance care plan and how many of these had advance care planning (ACP) documents in their general practice records.Methods A retrospective cohort study was conducted of patient hospital records with manual linkage to general practice records. The large regional hospital in Victoria, Australia has a catchment population in excess of 300,000 people. The study sample was patients aged 75 years and over who died in the hospital between 1 January 2016 and 31 December 2017. The hospital records of these patients were examined to identify those which did not have a system alert for ACP documents on the file. Alerted ACP documents were limited to those legislated in the state of Victoria: advance care plan, Enduring Power of Attorney (Medical Treatment) or Enduring Power of Guardianship. Where no ACP document system alert was found in the hospital record, the patient’s nominated general practice was consented to participate and the corresponding general practice record was examined. Data were analysed using descriptive statistics.Results Of the 406 patients who died in hospital, 76.1% (309) did not have a system alert for any ACP document. Of the 309 hospital records without a system alert, 144 (46.7%) corresponding general practice records were examined. Of these, 14.6% included at least one ACP document, including four advance care plans, that were not available in hospital.Conclusions Unless ACP documents are consistently communicated from general practice, patient’s preferences may be unknown during end-of-life care. It is important that both doctors and patients are supported to use connected electronic health records to ensure that documents are readily available to healthcare staff when they are required.
Higher activity of monodehydroascorbate reductase and lower activities of leaf and spike vacuolar invertase and glutathione S-transferase reveals higher number of grains per spike in spring wheat genotypes grown under well-watered and drought conditions
Authors: Shokat sajid , Großkinsky Dominik K. , Roitsch Thomas , Liu Fulai 
Published: June 2020

Abstract
Background: To improve our understanding about the physiological mechanism of grain yield reduction at anthesis, three spring wheat genotypes (L1, L2 and L3) having contrasting yield potential under drought in field were investigated under controlled greenhouse conditions., drought stress was imposed at anthesis stage by withholding irrigation until all plant available water was depleted, while well-watered control plants were kept at 95% pot water holding capacity. Results: Compared to genotype L1 and L2, pronounced decrease in grain number (NGS), grain yield (GY) and harvest index (HI) were found in genotype L3, mainly due to its greater kernel abortion (KA) under drought. A significant positive correlation of leaf monodehydroascorbate reductase (MDHAR) with both NGS and HI was observed. In contrast, significant negative correlations of glutathione S-transferase (GST) and vacuolar invertase (vacInv) both within source and sink with NGS and HI were found. Likewise, a significant negative correlation of leaf abscisic acid (ABA) with NGS was noticed. Moreover, leaf aldolase and cell wall peroxidase (cwPOX) activities were significantly and positively associated with TKW. Conclusion: Collectively, distinct physiological markers were correlating with yield traits and higher activity of leaf aldolase and cwPOX may be chosen as predictive bio-markers for higher TKW. Also, higher activity of MDHAR within the leaf can be selected as a predictive bio-marker for higher NGS in wheat under drought. Whereas, lower activity of vacInv and GST both within leaf and spike can be selected as bio-markers for higher NGS and HI. The results highlighted the role of antioxidant and carbohydrate-metabolic enzymes in the modulation of source-sink balance in wheat crops, which could be used as bio-signatures for breeding and selection of drought-resilient wheat genotypes for a future drier climate.
Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance via PTEN-mediated crosstalk between the PI3K/Akt and Erk/MAPKs signaling pathways in the skeletal muscles of db/db mice
Authors: Chen Guang , Fan Xiao-yan , Zheng Xiao-peng , Jin Yue-lei , Liu Ying , Liu Shuang-chun 
Published: June 2020

Abstract
Background: Globally, 1 in 11 adults have diabetes mellitus and 90% of the cases are type 2 diabetes mellitus. Asia is the epicenter of this global type 2 diabetes mellitus epidemic. Type 2 diabetes mellitus and its complications have contributed significantly to the burden of mortality and disability worldwide. Insulin resistance is a central defect in type 2 diabetes mellitus, and although multiple drugs have been developed to ameliorate insulin resistance, the limitations and accompanying side effects cannot be ignored. Thus more effective methods are required to improve insulin resistance. Methods: In the current study, db/m and db/db mice were injected with human umbilical cord-derived mesenchymal stem cells (HUC-MSCs) via tail vein injection, intraperitoneal injection and skeletal muscle injection. Body weight, fasting blood glucose and the survival rates were monitored. Furthermore, the anti-insulin resistance effects and potential mechanisms of transplanted HUC-MSCs were investigated in db/db mice in vivo . Results: The results showed that HUC-MSC transplantation by skeletal muscle injection was safer compared with tail vein injection and intraperitoneal injection, and the survival rate reached 100% in the skeletal muscle injection transplanted mice. HUC-MSCs can stabilize localization and differentiation in skeletal muscle tissue and significantly ameliorate insulin resistance. Potential regulatory mechanisms are associated with downregulation of inflammation; regulating the balance between PI3K/Akt and ERK/MAPK signaling pathway via PTEN, but was not associated with the IGF-1/IGF-1R signaling pathway. Conclusions: These results suggest HUC-MSC transplantation may be a novel therapeutic direction to prevent insulin resistance and increase insulin sensitivity, and skeletal muscle injection was the safest and most effective way.