bluuebunny/crossref_metadata_2025_split huggingface dataset:
Head Computed tomography during emergency department treat-and-release visit for headache is associated with increased risk of subsequent cerebrovascular disease hospitalization
Authors: Liberman Ava L. , Wang Cuiling , Friedman Benjamin W. , Prabhakaran Shyam , Esenwa Charles C. , Rostanski Sara K. , Cheng Natalie T. , Erdfarb Amichai , Labovitz Daniel L. , Lipton Richard B. 
Published: October 2020

Abstract

Objectives
The occurrence of head computed tomography (HCT) at emergency department (ED) visit for non-specific neurological symptoms has been associated with increased subsequent stroke risk and may be a marker of diagnostic error. We evaluate whether HCT occurrence among ED headache patients is associated with increased subsequent cerebrovascular disease risk.

Methods
We conducted a retrospective cohort study of consecutive adult patients with headache who were discharged home from the ED (ED treat-and-release visit) at one multicenter institution. Patients with headache were defined as those with primary ICD-9/10-CM discharge diagnoses codes for benign headache from 9/1/2013-9/1/2018. The primary outcome of cerebrovascular disease hospitalization was identified using ICD-9/10-CM codes and confirmed via chart review. We matched headache patients who had a HCT (exposed) to those who did not have a HCT (unexposed) in the ED in a one-to-one fashion using propensity score methods.

Results
Among the 28,121 adult patients with ED treat-and-release headache visit, 45.6% (n=12,811) underwent HCT. A total of 0.4% (n=111) had a cerebrovascular hospitalization within 365 days of index visit. Using propensity score matching, 80.4% (n=10,296) of exposed patients were matched to unexposed. Exposed patients had increased risk of cerebrovascular hospitalization at 365 days (RR: 1.65: 95% CI: 1.18–2.31) and 180 days (RR: 1.62; 95% CI: 1.06–2.49); risk of cerebrovascular hospitalization was not increased at 90 or 30 days.

Conclusions
Having a HCT performed at ED treat-and-release headache visit is associated with increased risk of subsequent cerebrovascular disease. Future work to improve cerebrovascular disease prevention strategies in this subset of headache patients is warranted.
Enhancing Students’ Ability in Learning Process of Programming Language using Adaptive Learning Systems: A Literature Review
Authors: Anindyaputri Natasha Alyaa , Yuana Rosihan Ari , Hatta Puspanda 
Published: October 2020

Abstract
There have been some hindrances in the process of programming learning. An adaptive learning system, such as ELaC, Java Guide, and Java Grader provides an adaptable learning content that can accommodate the learning styles as well as preferences of each learning individual. Moreover, an adaptive learning system can help students of different capabilities in learning programming. This study examined the outcomes of the implementation of an adaptive learning system in programming learning, as well as some finding results that were conducted according to the Systematic Literature Review framework. The research questions of this research were: problems faced during learning of programming as a background of system development, advantages and disadvantages of the system characteristics, technology, features, and effectiveness of the developed adaptive learning system. This research produced concepts that are summed up upon the related resources. The results of this study summarized whether the use of adaptive learning systems in learning programming could overcome the problems encountered during the learning process.
Hydroxyapatite/polyetheretherketone nanocomposites for selective laser sintering: Thermal and mechanical performances
Authors: Lai Wenwen , Wang Yan , Fu Hua , He Junkun 
Published: October 2020

Abstract
In this article, the thermal and mechanical properties of hydroxyapatite (HA)/polyetheretherketone (PEEK) nanocomposites were investigated. The surface of the HA particles was modified by stearic acid. Subsequently, the modified HA and PEEK were ultrasonically dispersed in ethanol and then subjected to drying and ball milling treatments. By controlling the concentration of modified HA, HA/PEEK nanocomposite powders containing various amounts of modified HA were successfully prepared. The tensile strength, impact strength, and flexural strength of the nanocomposite reached maximum values at 2.5 wt% HA and were 18.5%, 38.2%, and 5.7% higher than those of the pure PEEK, respectively. Moreover, the flexural modulus of the HA/PEEK nanocomposites increased at 2.5 wt% HA and was approximately 30% higher than that of the pure PEEK. The thermal property measurements (differential scanning calorimetry and thermogravimetric analysis) showed that the nanocomposites with 2.5 wt%-modified HA exhibited enhanced thermal stability as compared to the pure PEEK, showing potential for selective laser sintering.
Seismic characteristics of polygonal fault systems in the Great South Basin, New Zealand
Authors: Jitmahantakul Sukonmeth , Chenrai Piyaphong , Kanjanapayont Pitsanupong , Kanitpanyacharoen Waruntorn 
Published: October 2020

Abstract
A well-developed multi-tier polygonal fault system is located in the Great South Basin offshore New Zealand’s South Island. The system has been characterised using a high-quality three-dimensional seismic survey tied to available exploration boreholes using regional two-dimensional seismic data. In this study area, two polygonal fault intervals are identified and analysed, Tier 1 and Tier 2. Tier 1 coincides with the Tucker Cove Formation (Late Eocene) with small polygonal faults. Tier 2 is restricted to the Paleocene-to-Late Eocene interval with a great number of large faults. In map view, polygonal fault cells are outlined by a series of conjugate pairs of normal faults. The polygonal faults are demonstrated to be controlled by depositional facies, specifically offshore bathyal deposits characterised by fine-grained clays, marls and muds. Fault throw analysis is used to understand the propagation history of the polygonal faults in this area. Tier 1 and Tier 2 initiate at about Late Eocene and Early Eocene, respectively, based on their maximum fault throws. A set of three-dimensional fault throw images within Tier 2 shows that maximum fault throws of the inner polygonal fault cell occurs at the same age, while the outer polygonal fault cell exhibits maximum fault throws at shallower levels of different ages. The polygonal fault systems are believed to be related to the dewatering of sedimentary formation during the diagenesis process. Interpretation of the polygonal fault in this area is useful in assessing the migration pathway and seal ability of the Eocene mudstone sequence in the Great South Basin.
Detecting myocardial scar using electrocardiogram data and deep neural networks
Authors: Gumpfer Nils , Grün Dimitri , Hannig Jennifer , Keller Till , Guckert Michael 
Published: October 2020

Abstract
Ischaemic heart disease is among the most frequent causes of death. Early detection of myocardial pathologies can increase the benefit of therapy and reduce the number of lethal cases. Presence of myocardial scar is an indicator for developing ischaemic heart disease and can be detected with high diagnostic precision by magnetic resonance imaging. However, magnetic resonance imaging scanners are expensive and of limited availability. It is known that presence of myocardial scar has an impact on the well-established, reasonably low cost, and almost ubiquitously available electrocardiogram. However, this impact is non-specific and often hard to detect by a physician. We present an artificial intelligence based approach — namely a deep learning model — for the prediction of myocardial scar based on an electrocardiogram and additional clinical parameters. The model was trained and evaluated by applying 6-fold cross-validation to a dataset of 12-lead electrocardiogram time series together with clinical parameters. The proposed model for predicting the presence of scar tissue achieved an area under the curve score, sensitivity, specificity, and accuracy of 0.89, 70.0, 84.3, and 78.0%, respectively. This promisingly high diagnostic precision of our electrocardiogram-based deep learning models for myocardial scar detection may support a novel, comprehensible screening method.
Evaluation of antidiabetic effect of Cistus salviifolius L. (Cistaceae) in streptozotocin-nicotinamide induced diabetic mice
Authors: Sayah Karima , Mrabti Hanae Naceiri , Belarj Badia , Kichou Faouzi , Cherrah Yahia , El Abbes Faouzi My 
Published: October 2020

Abstract

Objectives

Cistus salviifoluis L. is a shrub from Cistaceae family used in many traditional medicines for the treatment of various diseases including diabetes mellitus. The aim of this study was to evaluate the in vivo antidiabetic potential of the aerial parts aqueous extract of Cistus salviifolius L. (CSA).

Methods
Experimental diabetes was induced in adult male mice by intra-peritoneal injection of Streptozotocin-nicotinamide (STZ-NC). CSA at a dose of 500 mg/kg was administered daily to the diabetic mice for four weeks. The effect of the extract on hyperglycemia, body weight, serum total cholesterol, triglycerides, hepatic and renal functional markers were determined. Histopathological examination of the mice pancreas was also performed. The diabetic animals treated with CSA were compared with animals treated by the standard drug metformin.

Results
Treatment with CSA showed a significant reduction in blood glucose, total triglycerides and creatinine levels and prevented the reduction of body weight caused by diabetes. Furthermore, histopathological analysis of the mice pancreas showed that the group treated with CSA reduced damage induced by STZ-NC on islets of Langerhans cells when compared to the diabetic control.

Conclusions
The results suggest that the aqueous extract of Moroccan C. salviifolius L. possesses beneficial effect on treatment of diabetes.
Morbidity profile of patients seeking Naturopathy and Yoga treatment in South India: A descriptive study
Authors: Panneerselvam Naresh Kumar , Ravindran Dhilip , Kathiresan Arunthathi 
Published: October 2020

Abstract

Background
Yoga and Naturopathy (Y&N) is one of the approved Complementary and Traditional systems of Medicine practiced in India. Unlike other systems, it is a drugless system aimed to optimize and facilitate the inherent ability of the human body to heal itself. There is lack of literature on the type of patients seeking Yoga and Naturopathy treatments in India. This study was designed with an objective to assess the morbidity profile of the in-patients treated in a Naturopathy and Yoga hospital.

Methods
Descriptive study design based on clinical case records. Six hundred and four cases treated as in-patients between April 2017 and July 2018 was analyzed.

Results
The average age of the patients was 47.4 (SD ± 16.1) years, with 56% were females and 44% males. About 50 different types of morbidity ranging from general rejuvenation to chronic diseases had been reported. Highest reported diseases were chronic in nature, with higher reporting for multiple system morbidity, followed by Obesity, Diabetes Mellitus, Hypertension, Arthritis, and Back pain. Variations were observed in the morbidities based on age and gender of the patients. The median duration of treatment was 8 days.

Conclusions
Patients seek Yoga & Naturopathy care mainly for chronic conditions, further observations on treatment outcomes, quality of life, and treatment seeking behavior can be explored for the efficacy and feasibility of Yoga & Naturopathy care in managing chronic diseases.
Error analysis of higher order Trace Finite Element Methods for the surface Stokes equation
Authors: Jankuhn Thomas , Olshanskii Maxim A. , Reusken Arnold , Zhiliakov Alexander 
Published: October 2020

Abstract
The paper studies a higher order unfitted finite element method for the Stokes system posed on a surface in ℝ3. The method employs parametric P

k
-P

k−1 finite element pairs on tetrahedral bulk mesh to discretize the Stokes system on embedded surface. Stability and optimal order convergence results are proved. The proofs include a complete quantification of geometric errors stemming from approximate parametric representation of the surface. Numerical experiments include formal convergence studies and an example of the Kelvin–Helmholtz instability problem on the unit sphere.
People also avoid repetition in sentence comprehension: Evidence from multiple postposition constructions in Korean
Authors: Shin Gyu-Ho 
Published: October 2020

Abstract
Repetition avoidance, one characteristic of human cognition, affects human behaviour to a great extent. The present study aims to extend the understanding of repetition avoidance to sentence comprehension in Korean, a language typologically different from the major languages that have been investigated for this issue. I measured the degree of acceptability and reaction times for two types of multiple postposition constructions in Korean, each of which has two grammatical patterns involving postposition alternations (dative-accusative and accusative-accusative for the dative construction; topic-nominative and nominative-nominative for the double subject construction). Results showed that the patterns involving repetition of postpositions were dispreferred over those without the repetition, and that by-pattern reaction times within each construction type were modulated by the postposition types repeated in the patterns. The findings of this study support the role of repetition avoidance for sentence comprehension in Korean (and perhaps beyond), and suggest an interplay between a domain-general factor (repetition avoidance) and language-specific knowledge (postpositions).
Circular RNA circ_SETD2 represses breast cancer progression via modulating the miR-155-5p/SCUBE2 axis
Authors: Shen Yuanyuan , Zhang Mengmeng , Da Liangshan , Huang Wei , Zhang Congjun 
Published: October 2020

Abstract
Breast cancer (BC) is the leading cause of cancer deaths in women worldwide. Circular RNA circ_SETD2 (circ_SETD2), also termed as hsa_circ_0065173, is reported to be abnormally expressed in BC. Nevertheless, the role and mechanism of circ_SETD2 in BC are unclear. Expression of circ_SETD2, miR-155-5p, and SCUBE2 mRNA was evaluated by quantitative real-time polymerase chain reaction. Cell cycle progression, proliferation, apoptosis, migration, and invasion were determined by flow cytometry, MTT, and transwell assays. The relationship between circ_SETD2 or SCUBE2 and miR-155-5p was verified through a dual-luciferase reporter assay. The role of circ_SETD2 in BC in vivo was confirmed by a xenograft assay. circ_SETD2 and SCUBE2 were downregulated, while miR-155-5p was upregulated in BC tissues and cells. Both circ_SETD2 and SCUBE2 elevation arrested cell cycle progression, inhibited cell proliferation, migration, and invasion, and accelerated cell apoptosis in BC cells. Moreover, circ_SETD2 upregulation repressed BC growth in vivo. Importantly, circ_SETD2 modulated SCUBE2 expression through competitively binding to miR-155-5p in BC cells. Also, the inhibitory impacts of circ_SETD2 enhancement on the malignant behavior of BC cells were restored by miR-155-5p overexpression. Besides, SCUBE2 silencing abolished miR-155-5p downregulation mediated effects on the malignant behavior of BC cells. Therefore, circ_SETD2 curbed BC progression via upregulating SCUBE2 via binding to miR-155-5p.
Reflectionless excitation of arbitrary photonic structures: a general theory
Authors: Stone A. Douglas , Sweeney William R. , Hsu Chia Wei , Wisal Kabish , Wang Zeyu 
Published: October 2020

AbstractWe outline and interpret a recently developed theory of impedance matching or reflectionless excitation of arbitrary finite photonic structures in any dimension. The theory includes both the case of guided wave and free-space excitation. It describes the necessary and sufficient conditions for perfectly reflectionless excitation to be possible and specifies how many physical parameters must be tuned to achieve this. In the absence of geometric symmetries, such as parity and time-reversal, the product of parity and time-reversal, or rotational symmetry, the tuning of at least one structural parameter will be necessary to achieve reflectionless excitation. The theory employs a recently identified set of complex frequency solutions of the Maxwell equations as a starting point, which are defined by having zero reflection into a chosen set of input channels, and which are referred to as R-zeros. Tuning is generically necessary in order to move an R-zero to the real frequency axis, where it becomes a physical steady-state impedance-matched solution, which we refer to as a reflectionless scattering mode (RSM). In addition, except in single-channel systems, the RSM corresponds to a particular input wavefront, and any other wavefront will generally not be reflectionless. It is useful to consider the theory as representing a generalization of the concept of critical coupling of a resonator, but it holds in arbitrary dimension, for arbitrary number of channels, and even when resonances are not spectrally isolated. In a structure with parity and time-reversal symmetry (a real dielectric function) or with parity–time symmetry, generically a subset of the R-zeros has real frequencies, and reflectionless states exist at discrete frequencies without tuning. However, they do not exist within every spectral range, as they do in the special case of the Fabry–Pérot or two-mirror resonator, due to a spontaneous symmetry-breaking phenomenon when two RSMs meet. Such symmetry-breaking transitions correspond to a new kind of exceptional point, only recently identified, at which the shape of the reflection and transmission resonance lineshape is flattened. Numerical examples of RSMs are given for one-dimensional multimirror cavities, a two-dimensional multiwaveguide junction, and a multimode waveguide functioning as a perfect mode converter. Two solution methods to find R-zeros and RSMs are discussed. The first one is a straightforward generalization of the complex scaling or perfectly matched layer method and is applicable in a number of important cases; the second one involves a mode-specific boundary matching method that has only recently been demonstrated and can be applied to all geometries for which the theory is valid, including free space and multimode waveguide problems of the type solved here.
Crystal structure of 2-hydroxy-4-methoxy benzaldehyde, C8H8O3
Authors: Ndima Lubabalo , Hosten Eric C. , Betz Richard 
Published: October 2020

Abstract
C8H8O3, monoclinic, P21/c (no. 14), a = 6.3037(3) Å, b = 33.102(2) Å, c = 7.0471(4) Å, β = 102.105(3)°, V = 1437.79(14) Å3, Z = 8, R

gt
(F) = 0.0433, wR

ref
(F
2) = 0.1087, T = 200 K.
Crystal structure of N-benzyl-N-nicotinoyl-nicotine amide C19H15N3O2
Authors: Hosten Eric C. , Betz Richard 
Published: October 2020

Abstract
C19H15N3O2, monoclinic, P21/c (no. 14), a = 18.4336(13) Å, b = 6.0321(4) Å, c = 15.0585(10) Å, β = 112.171(3)°, V = 1550.60(18) Å3, Z = 4, Rgt
(F) = 0.0535, wRref
(F
2) = 0.1298, T = 200 K.
The crystal structure of 2,6-difluorophenol, C6H4F2O
Authors: Manana Pholani , Cuthbertson Jarryd , Hosten Eric C. , Betz Richard 
Published: October 2020

Abstract

C
6

H
4

F
2

O

${\text{C}}_{6}{\text{H}}_{4}{\text{F}}_{2}\text{O}$

, orthorhombic,

P

2
1

2
1

2
1

$P{2}_{1}{2}_{1}{2}_{1}$

(no. 19), a = 4.9287(5) Å, b = 10.1752(8) Å, c = 10.9156(10) Å, V = 547.42(9) Å3, Z = 4,

R

g
t

${R}_{gt}$

(F) = 0.0248,

w

R

ref

$w{R}_{\text{ref}}$

(

F
2

${F}^{2}$

) = 0.0705, T = 200 K.CCDC no.: 2025946
A note on the acoustic environment in a usually quiet residential area after the ‘state of emergency’ declaration due to COVID-19 pandemic in Japan was lifted: supplementary survey results in post-emergency situations
Authors: Sakagami Kimihiro 
Published: October 2020

Abstract
In a preceding report (UCL Open: Environment, 2020;1;6), an example of results on changes in the acoustic environment from a local-scale survey in a quiet residential area during and after the ‘state of emergency’ due to COVID-19 pandemic in Japan is presented: the noise level was 1–2 dBA lower during the state of emergency, which is smaller than reported from large cities. This note presents the results of a follow-up survey in the same area to provide some more examples to gain an insight into the acoustic environment in this area. In this note, the measurement results of noise levels in June 2020, a few weeks after the cancellation of the state of emergency, are mainly reported. As the results are almost the same as those from during the state of emergency, we can infer that either the noise level was reduced in June to a level that was almost the same as that during the state of emergency, or the noise level after its cancellation in May was possibly higher than usual. In either case, the change in noise level was small, and it was difficult to conclude which case was true.
Nominal predication withestar
Authors: Bazaco Carmelo , González-Rivera Melvin 
Published: October 2020

AbstractSpanish is a dual copula system —serandestar. According to traditional interpretations of their distribution,estardoes not take nominal complements. Instead, this type of complements appears with the copula ser. There are, however, some counterexamples to this rule. On the one hand, we have examples such asPepe estuvo torero ayer‘Pepe was like a bullfighter yesterday.’ In this example, the noun torero does not have its usual interpretation, but rather it refers to the prototypical qualities associated with bullfighters — bravery, unfazed by danger. In this manner, the restriction that Spanish imposes on the copula estar regarding NP complementation does not seem apply in cases where the NP does not provide an identificational interpretation, but rather one associated with the prototypical qualities associated with the noun. A second case in whichestarcan take nominal complements can be seen in examples such asEsta película está una masa‘This movie is pretty cool.’ This type ofestarpredication has a different interpretation than the ones presented in the previous example. While the former provides a predication denoting the properties associated with the noun, the nouns in the latter are expressing a measure of quality regarding their subject. The subjectspelícula‘movie’ is not being identified with the prototypical qualities of a mass but rather are expressions of high quality. In this respect, theestarpredication in this example can be ascribed to the evidential uses ofestar. Not every dialect of Spanish can produce examples such as the ones found in theestáuna masa example, while data similar toestá torerois common in all the dialectal continuum. The focus of this investigation is to examine these two types of nominal complements withestarand provide an analysis of the differences between them, as well as provide an explanation regarding their acceptability inestarpredications.