bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bases conceptuales para el estudio interdisciplinario del sistema jurídico y las futuras generaciones: Perspectiva teórica y empírica desde el Derecho Ambiental
Authors: Foy Valencia Pierre 
Published: November 2020

El presente artículo tiene como objetivo principal sentar en nuestro medio las bases iniciáticas o preliminares para el estudio interdisciplinario del Sistema Jurídico en relación con las futuras generaciones, aplicando conceptual y empíricamente al Derecho ambiental con una perspectiva intergeneracional.El autor se adentra en la doctrina actual relevante y esboza las principales líneas de investigación del tópico, proponiendo al estudioso las diversas áreas que integran el actual debate respecto a las herramientas jurídicas que coadyuvarían a la conservación de la Tierra.
Jornada laboral: importancia y aspectos críticos de su regulación
Authors: Ávalos Rodríguez Brian 
Published: November 2020

En el presente artículo se analizan los beneficios de la limitación de la jornada laboral y las razones por las cuales dicha medida beneficia a los trabajadores, al Estado y a la sociedad en su conjunto. El autor hace referencia a la regulación de la jornada laboral en el ordenamiento jurídico peruano y presenta propuestas que permiten mayor flexibilidad para el trabajador, de forma que este pueda desarrollarse plenamente.
Igualdad salarial entre hombres y mujeres: defensas y excepciones
Authors: Blume Moore Iván 
Published: November 2020

Desde la expedición de una serie de normas que prohíben la discriminación remunerativa entre hombres y mujeres, se ha concretizado la efectividad de dicha prohibición en el Perú. Sin embargo, la prohibición a la discriminación remunerativa no opera de manera absoluta, en la cual pueden darse excepciones y justificaciones al desbalance remunerativo entre hombres y mujeres.
El presente artículo explora las normas relevantes y hace énfasis en las excepciones y justificaciones a la prohibición a la discriminación remunerativa, examinando los casos donde estos podrían desenvolverse.
¿Empresas tercerizadoras y trabajadores no registrados?: a propósito de la Casación Laboral 11312-2016-Junín
Authors: Guzmán Estrada Lucía Alejandra 
Published: November 2020

El presente artículo tiene como objetivo analizar los problemas jurídicos identificados respecto a los criterios jurisprudenciales empleados para declarar la desnaturalización, en particular ante la figura de la tercerización, a partir de la Casación Laboral 11312-2016 Junín, sentencia emitida por la Segunda Sala Constitucional y Social de la Corte Suprema del Perú.
La autora inicia el análisis desarrollando un breve marco jurídico sobre la tercerización de servicios en el Perú para, posteriormente, esbozar los antecedentes de la Casación Laboral 11312-2016-Junín. A continuación, analiza sus fundamentos e identifica, critica y problematiza dos problemas jurídicos. Finalmente, a modo de conclusión, expone un juicio crítico sobre la resolución del caso.
Mediación laboral y su impacto en las relaciones colectivas de trabajo en Perú
Authors: Cadillo Ángeles Carlos 
Published: November 2020

En el presente artículo se analiza el impacto de la mediación laboral en las relaciones de trabajo en el Perú y cómo ese mecanismo alternativo de solución supone una manera idónea de resolver conflictos. Para ese fin se analiza la importancia de la mediación laboral en los conflictos que surgen entre los empleadores y las organizaciones sindicales.
El autor busca explicar por qué resulta necesario revalorar la mediación laboral y devolverle el significado, ya que supone un ambiente en el cual las partes podrán resolver los conflictos de manera pacífica.
Apuntes a la responsabilidad civil derivada de despido incausado o fraudulento en el sistema peruano: la retórica de los punitive damages y la desnaturalización del lucro cesante
Authors: Campos García Héctor 
Published: November 2020

La Corte Suprema peruana ha considerado en el V Pleno Jurisdiccional Laboral que las remuneraciones dejadas de percibir en los casos de despido incausado o fraudulento tienen naturaleza indemnizatoria, lo cual ha ocasionado que se recurra de forma retórica a la noción del “daño punitivo” y que se fijen reglas diferenciadas sin justificación alguna con relación al despido nulo.En el artículo se exponen las razones por las cuales la Corte Suprema asumió tal posición y se formula una crítica a la misma. Finalmente, se expone una propuesta de solución para que los magistrados no apliquen el V Pleno Laboral en casos concretos.
El derecho del trabajo en la era del Turbocapitalismo
Authors: Arias Domínguez Ángel 
Published: November 2020

Con el nacimiento de la economía capitalista, el Derecho del Trabajo surgió para dar respuesta a las necesidades de los trabajadores. Pero, tras el paso a una economía turbocapitalista, en que la velocidad y el consumo redefinen la dinámica laboral, se reclama la adaptación del Derecho del Trabajo a este nuevo contexto.El autor propone la necesidad de una revisión histórica al contenido del Derecho del Trabajo. Parte de situar el contexto económico que originó su surgimiento, para, posteriormente, identificar cuáles son sus elementos esenciales y su fi nalidad. Finalmente, detalla los cambios introducidos por el turbocapitalismo en la dinámica de las relaciones laborales y propone una relectura de los elementos esenciales del Derecho del Trabajo en clave de las exigencias de esta nueva etapa de la economía.
La asignación de servicios en los contratos de consorcios sin contabilidad independiente y su inafectación según la legislación del Impuesto General a las Ventas
Authors: Escalante Alpaca Gonzalo Alonso 
Published: November 2020

La inafectación se configura como una institución legal mediante la cual se exime de cualquier imputación de carga fiscal a los hechos económicos que no se encuentran subsumidos dentro de la hipótesis de incidencia tributaria.
Este artículo analiza la configuración del supuesto de inafectación prevista en el inciso n) del artículo 2 de la Ley del Impuesto General a las Ventas en lo relacionado a la asignación de servicios dentro de un contrato de consorcio sin contabilidad independiente en el cual uno de los consorciados ejerce la función de operador.
A Study on Finding the Factors, Hindering the use of digital wallets among youth in Developing Countries
Authors: Nimansa A.T. , Kuruwitaarachchi N. 
Published: November 2020

<div><p class="normal">A digital wallet or eWallet is a mobile based software application that securely persists consumer’s payment information and passwords for numerous payment methods. By using an eWallet, users can complete their transactions easily and quickly with technologies such as Quick Response (QR) and near-field communications (NFC). In the modern world, people use digital wallets to engage in financial and non-financial activities using the internet. It stores physical financial instruments digitally and provides high availability to convenience to the user. Typically, to facilitate high security to those financial assets, in the digital wallet of the user, and to maintain reliability and availability, mobile application developing organizations follow different authorization mechanisms. The problem prevailing in a developing country similar to Sri Lanka is the less use of digital wallets in day to day transactions. The final outcome of the research will be to find the factors which affect the use of digital wallets in Sri Lankan students who study in western province universities. The advantage of finding the mentioned factors is to help eWallet developers to enhance their products to attract and onboard more customers. The eWallet developers can think about these measures when developing a solution and use it to promote the application. Further, when developers create an optimal solution, the consumer of eWallets will be highly benefited with an efficient financial application.</p></div>
COMPARATIVE TAPHONOMY OF DEEP-SEA AND SHALLOW-MARINE ECHINOIDS OF THE GENUS ECHINOCYAMUS
Authors: GRUN TOBIAS B. , MIHALJEVIĆ MORANA , WEBB GREGORY E. 
Published: November 2020

ABSTRACT
The infaunal living clypeasteroid echinoid genus Echinocyamus is considered a model organism for various ecological and paleontological studies since its distribution ranges from the polar regions to the tropics, and from shallow-marine settings to the deep-sea. Deep-sea analyses of this genus are rare, but imperative for the understanding and function of these important ecosystems. During the 2012 Southern Surveyor expedition, 35 seamounts off the east coast of Australia were dredged in depths greater than 800 m. Of these, six dredges contained a total of 18 deep-sea Echinocyamus tests. The tests have been analyzed for taphonomic alterations including abrasion patterns, macro-borings, micro-borings, depressions on the test, test staining, test filling, encrustation, and fragmentation. Findings are interpreted in the context of the deep-sea setting and are compared to Echinocyamus samples from shallow-water environments. Results show that abrasion in deep-sea environments is generally high, especially in ambulacral and genital pores indicating that tests can persist for a long time on the seafloor. This contrasts with shallow-water Echinocyamus that show lower abrasion due to early test destruction. Macro-borings are present as single or paired holes with straight vertical profiles resembling Lithophaga borings. Micro-borings are abundant and most likely the result of sponge or fungal activity. Depressions on the tests, such as scars or pits, are likely the result of trauma or malformation during ontogeny. Test staining is common, but variable, and is associated with FE/Mn oxidation and authigenic clays based on elemental analyses. Test filling occurs as loose or lithified sediment. Encrustation is present in the form of rudimentary crusts and biofilms. No macro-organisms were found on the tests. Biofilm composition differs from shallow-water environments in that organisms captured in the biofilm reflect aphotic conditions or sedimentation of particles from higher in the water column (e.g., coccoliths). Fragmentation is restricted to the apical system and pore regions. Results of this first comparative study on deep-sea Echinocyamus from Australian seamounts show that the minute tests can survive for a long time in these settings and undergo environmental specific taphonomic processes reflected in various taphonomic alterations.
Enhancing Heavy-Oil-Recovery Efficiency by Combining Low-Salinity-Water and Polymer Flooding
Authors: Zhao Yang , Yin Shize , Seright Randall S. , Ning Samson , Zhang Yin , Bai Baojun 
Published: November 2020

SummaryCombining low-salinity-water (LSW) and polymer flooding was proposed to unlock the tremendous heavy-oil resources on the Alaska North Slope (ANS). The synergy of LSW and polymer flooding was demonstrated through coreflooding experiments at various conditions. The results indicate that the high-salinity polymer (HSP) (salinity = 27,500 ppm) requires nearly two-thirds more polymer than the low-salinity polymer (LSP) (salinity = 2,500 ppm) to achieve the target viscosity at the condition of this study. Additional oil was recovered from LSW flooding after extensive high-salinity-water (HSW) flooding [3 to 9% of original oil in place (OOIP)]. LSW flooding performed in secondary mode achieved higher recovery than that in tertiary mode. Also, the occurrence of water breakthrough can be delayed in the LSW flooding compared with the HSW flooding. Strikingly, after extensive LSW flooding and HSP flooding, incremental oil recovery (approximately 8% of OOIP) was still achieved by LSP flooding with the same viscosity as the HSP. The pH increase of the effluent during LSW/LSP flooding was significantly greater than that during HSW/HSP flooding, indicating the presence of the low-salinity effect (LSE). The residual-oil-saturation (Sor) reduction induced by the LSE in the area unswept during the LSW flooding (mainly smaller pores) would contribute to the increased oil recovery. LSP flooding performed directly after waterflooding recovered more incremental oil (approximately 10% of OOIP) compared with HSP flooding performed in the same scheme. Apart from the improved sweep efficiency by polymer, the low-salinity-induced Sor reduction also would contribute to the increased oil recovery by the LSP. A nearly 2-year pilot test in the Milne Point Field on the ANS has shown impressive success of the proposed hybrid enhanced-oil-recovery (EOR) process: water-cut reduction (70 to less than 15%), increasing oil rate, and no polymer breakthrough so far. This work has demonstrated the remarkable economical and technical benefits of combining LSW and polymer flooding in enhancing heavy-oil recovery.
A global analysis of CNVs in Chinese indigenous fine-wool sheep populations using whole-genome resequencing
Authors: Yuan Chao , Lu Zengkui , Guo Tingting , Yue Yaojing , Wang Xijun , Wang Tianxiang , Zhang Yajun , Hou Fujun , Niu Chune , Sun Xiaopin , Zhao Hongchang , Zhu Shaohua , Liu Jianbin , Yang Bohui 
Published: November 2020

Abstract
Background: Copy number variation (CNV) is an important source of genetic variation that has a significant influence on phenotypic diversity, important economic traits and the evolution of livestock species. In this study, the genome-wide CNV distribution characteristics of 32 fine-wool sheep from three breeds were analyzed using resequencing. Results: A total of 1747604 CNVs were detected in this study, and 7228 CNV regions (CNVR) were obtained after merging overlapping CNVs; these regions accounted for 2.17% of the sheep reference genome. The average length of the CNVRs was 4307.17 bp. “Deletion” events took place more frequently than “duplication” or “both” events. The CNVRs obtained overlapped with previously reported sheep CNVRs to variable extents (4.39%–55.46%). Functional enrichment analysis showed that the CNVR-harboring genes were mainly involved in sensory perception systems, nutrient metabolism processes, and growth and development processes. Furthermore, 1855 of the CNVRs were associated with 166 quantitative trait loci (QTL), including milk QTLs, carcass QTLs, and health-related QTLs, among others. In addition, the 32 fine-wool sheep were divided into horned and polled groups to analyze for the selective elimination of CNVRs, and it was found that the relaxin family peptide receptor 2 ( RXFP2 ) gene was strongly influenced by selection. Conclusions: In summary, we constructed a genomic CNV map for Chinese indigenous fine-wool sheep using resequencing, thereby providing a valuable genetic variation resource for sheep genome research, which will contribute to the study of complex traits in sheep.
Interaction of Arsenophonus with Wolbachia in Nilaparvata lugens
Authors: Guo Huifang , Wang Na , Niu Hongtao , Zhao Dongxiao , Zhang Zhichun 
Published: November 2020

Abstract
Background Co-infection of endosymbionts in the same host is ubiquitous, and the interactions of the most common symbiont Wolbachia with other symbionts, including Spiroplasma et al., in invertebrate organisms have received increasing attention. However, the interactions between Wolbachia and Arsenophonus, another widely distributed symbiont in nature, are poorly understood. We tested the co-infection of Wolbachia and Arsenophonus in different populations of Nilaparvata lugens and investigated whether co-infection affected the population size of the symbionts in their host.Results A significant difference was observed in the co-infection incidence of Wolbachia and Arsenophonus among 5 populations of N. lugens from China, with nearly half of the individuals in the Zhenjiang population harbouring the two symbionts simultaneously, and the rate of occurrence was significantly higher than that of the other 4 populations. The Arsenophonus density in the superinfection line was significantly higher only in the Maanshan population compared with that of the single-infection line. Differences in the density of Wolbachia and Arsenophonus were found in all the tested double-infection lines, and the dominant symbiont species varied with the population only in the Nanjing population, with Arsenophonus the overall dominant symbiont. Conclusions Wolbachia and Arsenophonus could coexist in N. lugens, and the co-infection incidence varied with the geographic populations. Antagonistic interactions were not observed between Arsenophonus and Wolbachia, and the latter was the dominant symbiont in most populations.
Age and education as factors associated with medication literacy: a community pharmacy perspective.
Authors: Plaza-Zamora Javier , Legaz Isabel , Osuna Eduardo , Pérez-Cárceles M. D. 
Published: November 2020

Abstract
Background: Aging implies a higher prevalence of chronic pathologies and a corresponding increase in medication. The correct adherence and use of the medication are prerequisites for reducing risks of disease progression, comorbidity, and mortality. Medication literacy (ML) is the specific ability to safely access and understand the information available concerning medication, and to act accordingly. Currently, there are few specific instruments that ascertain the extent of ML in the general population. The aim of this work was to analyse ML in a large cohort of pharmacy customers. Methods: A total of 400 community pharmacy clients were analyzed to assess the level of ML (documental and numeracy) through the validated MedLitRxSE tool.Results: The results showed that out of a total of 400 community pharmacy clients only 136 (34%) had an adequate degree of ML, while the rest of the clients (n=264; 66%) were adjudged not to have this ability. Statistically significant differences were found between the different age groups in terms of ML (P<0.001; OR=0.312; 95% CI: 0.195-0.499), the 51-65 and ˃65-year age groups having a lower frequency of adequate ML (23.5% and 7.1%, respectively) than the rest of the age groups. A statistically significant increase in adequate ML was observed as the academic level of the clients increased (P <0.001; OR=15.403; 95% CI: 8.109-29.257). Multivariate logistic regression confirmed the influence of both variables on ML. Conclusions: An inadequate ML level was found in community pharmacy clients over the age of 51, and also in those with primary or non-formal studies. Our data add to our knowledge about ML, and should pharmacists and other health professionals to adopt new strategies to prevent, or at least reduce, errors in taking medicines, thus avoiding the undesirable effects of any misuse.
Validation and psychometric evaluation of the Dutch Person-centred care of Older People with cognitive impairment in Acute Care (POPAC)
Authors: Keuning-Plantinga Annette , Finnema Evelyn , Krijnen Wim , Edvardsson David , Roodbol Petrie 
Published: November 2020

Abstract
Background: Person-centered care is the preferred model for caring for people with dementia. Knowledge of the level of person-centered care is essential for improving the quality of care for patients with dementia. The Person-centred care of Older People with cognitive impairment in Acute Care scale (POPAC) is a tool to determine the level of person-centered care. This study aimed to translate and validate the Dutch POPAC and evaluate its psychometric properties to enable international comparison of data and outcomes.Methods: After double-blinded forward and backward translations, a total of 159 nurses recruited from six hospitals (114) and via social media (45) completed the POPAC. By performing confirmatory factor analysis, the construct validity was tested. Cronbach’s alpha scale was utilized to establish the internal consistency.Results: The confirmatory factor analysis showed that the Confirmatory Fit Index (0.89) was slightly smaller than the cut-off value of 0.9. The Root Mean Square Error of Approximation (0.075, p=0.012, CI 0.057-0.092) and the Standardized Root Mean Square Residual (0.063) were acceptable with values less than 0.08. Findings confirm a three-dimensional structure. The loadings of the items (0.69-0.77) indicate that these are strong associated with each of the factors. This study confirms that deleting Item 5 improves the Cronbach’s alpha of the instrument as well as of the subscale. Instead of deleting this item, we suggest considering rephrasing it into a positive item.Conclusions: Our findings suggest that the Dutch POPAC is sufficiently valid and reliable and can be utilized for assessing person-centered care in acute care hospitals. The study enables nurses to interpret and compare person-centered care levels in wards and hospital levels between regions and countries. The results form an important basis for improving the quality of care and nurse-sensitive outcomes, such as preventing complications and hospital stay length.
EGFL6 promotes colorectal cancer cell growth and mobility and the anti-cancer property of anti-EGFL6 antibody
Authors: Sung Ting-Yi , Huang Han-Li , Cheng Chun-Chun , Chang Fu-Ling , Wei Po-Li , Cheng Ya-Wen , Huang Cheng-Chiao , Lee Yu-Ching , HuangFu Wei-Chun , Pan Shiow-Lin 
Published: November 2020

Abstract
BackgroundA reliable cancer biomarker will be critical for advanced colorectal cancer (CRC) therapeutic approaches since current treatments are limited to certain patient characteristics, such as age, sex, comorbidities and patients received self-expandable metal stents implantations. The association of epidermal growth factor-like domain 6 (EGFL6) with cancer development has been reported. Here, we focused on the role of EGFL6 in CRC progression and its clinical relevance. An anti-EGFL6 antibody was generated by phage display technology to investigate the potential therapeutic efficacy in CRC. Student t test, Kruskal-Wallis test and multiple comparisons were used to statistical analysis results.ResultsSignificant EGFL6 expression was found in colon tissues from patients and spontaneous tumorigenesis mouse but not in normal tissue. Under hypoxia condition, EGFL6 expression were enhanced in protein and transcript-level. Furthermore, we found EGFL6 could enhance cancer cell migration, invasion and proliferation in CRC via up-regulating ERK/ AKT pathway, as well as reducing ADAMTS1 and Snail expression. We also found EGFL6 regulates cell abilities through EGFR/αvβ3 integrin receptors. By conducting animal experiments, our anti-EGFL6 antibody, EGFL6-E5-IgG, showed tumor inhibition and anti-metastasis ability. Furthermore, no impact on angiogenesis and wound healing by using EGFL6-E5-IgG were observed.ConclusionsWe demonstrated that EGFL6 plays a role in CRC tumorigenesis and tumor progression, indicating that EGFL6 is a potential cancer biomarker and therapeutic target worth further investigation.