bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS POTENSI WILAYAH BERBASIS PENGEMBANGAN SEKTOR PERIKANAN DI KABUPATEN KOTABARU
Authors: Fauzan Ginanjar Ilham , Kumalawati Rosalina , Adyatma Sidharta 
Published: May 2020

Potensi perikanan merupakan seluruh unsur pada sektor perikanan yang dapat dijadikan sebagai kekuatan dalam menyediakan kebutuhan manusia. Sektor perikanan basis dapat dijadikan sebagai acuan dalam pembangunan daerah perikanan di Kabupaten Kotabaru. Metode penelitian ini adalah metode deskriptif kuantitatif. Populasi dan sampel dalam penelitian ini adalah seluruh kecamatan di Kabupaten Kotabaru yang berjumah 21. Data sekunder adalah data yang diperoleh dari dokumen dan data yang telah tersedia pada buku mengenai perikanan di Kabupaten Kotabaru. Penelitian ini dilakukan bertujuan utuk mengkaji sektor basis dan non basis pada sektor perikanan di Kabupaten Kotabaru dan memetakan daerah perikanan basis dan non basis di Kabupaten Kotabaru. Hasil yang diperoleh dalam penelitian ini potensi perikanan tangkap laut basis di Kabupaten Kotabaru berjumlah 6 daerah kecamatan, dan 15 daerah kecamatan non basis. Pemetaan daerah basis ditandai dengan arsir warna hijau (Basis), kuning (Seimbang), dan biru (Non Basis). Potensi perikanan darat basis Kabupaten Kotabaru berjumlah 8 daerah kecamatan dan daerah non basis berjumlah 13 daerah kecamatan. Pemetaan daerah basis ditandai dengan arsir warna hijau (Basis), kuning (Seimbang), dan biru (Non Basis).
ANALISIS TINGKAT KETAHANAN PANGAN DI KABUPATEN BANJAR PROVINSI KALIMANTAN SELATAN
Authors: Fitriyani Fitriyani , Adyatma Sidharta , Kumalawati Rosalina 
Published: May 2020

Ketahanan pangan merupakan kondisi terpenuhinya pangan yang mencakup aspek ketersediaan pangan, akses pangan, dan pemanfaatan pangan untuk mewujudkan mayarakat yang berkualitas. Peta ketahanan dan kerentanan pangan atau Food Security and Vulnerability Atlas (FSVA) 2015 yang dihasilkan oleh Sekretariat Dewan Ketahanan Pangan menyatakan bahwa Kabupaten Banjar berstatus sedang (agak rawan pangan) prioritas 4. Kondisi agak rawan pangan menunujukkan bahwa Kabuapten Banjar menghadapi ancaman rawan pangan berdasarkan aspek ketahanan pangan. Metode penelitian yang digunakan yaitu dengan menggunakan metode analisis data sekunder. Metode analisis data sekunder terdiri atas metode pengumpulan data, metode pengolahan data, dan metode analisis data yang meliputi analisis deskriptif kuantitatif. Analisis deskriptif digunakan untuk mengetahui tingkat ketahanan pangan di 19 Kecamatan yang ada di Kabupaten Banjar. Hasil penelitian menunjukkan bahwa tingkat ketahanan pangan di Kabupaten Banjar Provinsi Kalimantan Selatan bervariasi terhadap sembilan indikator ketahanan pangan yang digunakan. Variasi tingkat ketahanan pangan di Kabupaten Banjar terbagi menjadi empat tingkatan, yaitu prioritas 2, prioritas 4, prioritas 5, dan prioritas 6. Prioritas 2 terdapat satu Kecamatan, prioritas 4 terdapat 4 Kecamatan, prioritas 5 terdapat 13 Kecamatan, dan Prioritas 6 terdapat satu Kecamatan.
Penerapan Model Gallery Walk Dalam Pembelajaran Geografi Di SMA Negeri 6 Banjarmasin
Authors: Nurhamidah Siti 
Published: May 2020

Guru sesuai dengan tugas pokoknya, mampu merencanakan, melaksanakan, dan melakukan penilaian terhadap proses pembelajaran di kelas. Guru diharapkan melakukan proses pembelajaran yang sesuai dengan kurikulum yang berlaku. Kurikulum 2013 yang dikembangkan menghendaki pengembangan kompetensi pengetahuan, sikap, dan keterampilan peserta didik. Strategi guru untuk meningkatkan pembelajaran geografi dengan menggunakan model Gallery Walk. Model Gallery Walk mampu mengeksplor dan melatih kecakapan abad 21 peserta didik. Penelitian tindakan kelas yang dilaksanakan untuk meningkatkan kemampuan peserta didik membuat peta penggunaan lahan. Pesertadidik yang menjadi subjek penelitian kelas XII IPS di SMAN 6 Banjarmasin. Jenis data yang dikumpulkan berupa kuantitatif dan kualitatif tentang keterampilan peserta didik membuat peta penggunaan lahan. Hasil yang dicapai, model Gallery Walk efektif meningkatkan keaktifan peserta didik kelas XII IPS mata pelajaran geografi. Peserta didik lebih aktif dalam mengajukan pertanyaan, mengkomunikasikan hasil karya peserta didik dan menyampaikan pengetahuan dari satu peserta didik ke peserta didik yang lain. Berdasarkan hasil observasi langsung kegiatan pameran dan instrumen angket. Selain itu, mampu meningkatkan hasil belajar peserta didik dalam ranah kognitif. Hasil ulangan harian menunjukkan nilai rata-rata kelas meningkat dari 67,94 pada menjadi 81,71.
Cinquante années d’amélioration génétique du porc en France : bilan et perspectives
Authors: BIDANEL Jean-Pierre , SILALAHI Parsaoran , TRIBOUT Thierry , CANARIO Laurianne , DUCOS Alain , GARREAU Hervé , GILBERT Hélène , LARZUL Catherine , MILAN Denis , RIQUET Juliette , SCHWOB Sandrine , MERCAT Marie-José , HASSENFRATZ Claire , BOUQUET Alain , BAZIN Christophe , BIDANEL Joel 
Published: May 2020

Cette synthèse fait le point sur les principales évolutions de l’amélioration génétique du porc en France depuis la loi sur l’élevage de 1966. Elle évoque rapidement les 20 premières années, qui ont fait l’objet d’une synthèse en 1986, puis décrit plus en détail les évolutions ultérieures. Les objectifs de sélection, initialement limités aux caractères de production, se sont complexifiés avec la prise en compte de la qualité de la viande, puis de la prolificité et enfin des aptitudes maternelles des truies. La mise en place d’une évaluation génétique utilisant la méthodologie du « BLUP - modèle animal » au milieu des années 1990 et le développement de l’insémination artificielle ont profondément changé le travail des sélectionneurs. Une nouvelle évolution majeure, la sélection génomique, a récemment été mise en place. La sélection a conduit à des améliorations importantes des performances pour les principaux caractères de l’objectif de sélection depuis 1970 : plus de 200 g de gain moyen quotidien, plus de 0,5 point d’indice de consommation, plus de 12 points de taux de viande maigre dans la carcasse, jusqu’à près de six porcelets nés vifs par portée supplémentaires. Ces évolutions favorables ont réduit l’empreinte environnementale de la production, mais ont également eu des effets défavorables : une augmentation la mortalité des porcelets avant sevrage et une plus grande hétérogénéité des performances. Les enjeux pour l’avenir en termes d’objectifs d’amélioration génétique (prise en compte de caractères liés au bien-être, à la robustesse et à l’adaptation…), de méthodes et d’outils sont ensuite discutés.
Le phosphore dans les systèmes d'élevage
Authors: DOURMAD Jean-Yves , BOUDON Anne , NARCY Agnès 
Published: May 2020

Le phosphore en agriculture constitue à la fois une ressource limitée et une source potentielle de pollution lorsqu'il est utilisé en excès comme fertilisant. Les systèmes d'élevages jouent un rôle particulièrement important dans les flux de phosphore, les déjections animales contribuant à l'échelle nationale à près de la moitié des apports sur les sols, avec une forte variabilité selon les régions. Les produits animaux contribuent aussi largement à la couverture des besoins pour l'alimentation humaine en apportant près de 60 % du phosphore total de la ration moyenne des Français. L'efficacité de rétention du phosphore par les animaux est très variable selon les espèces. La plus élevée est obtenue chez le poulet standard, suivi du porc, du poulet label rouge et de la vache laitière, les poules pondeuses et les vaches allaitantes présentant des efficacités plus faibles. Toutefois, à l'échelle du système de production, les pressions en phosphore organique sont plus faibles pour les élevages de ruminants qui disposent de plus de surface d'épandage. Ces dernières années l'amélioration des connaissances des besoins et de l'utilisation digestive du phosphore ont permis de réduire fortement les apports en phosphore et les rejets, avec pour les animaux monogastriques l'effet additionnel de l'utilisation de phytases. Les pertes de phosphore vers l'environnement étant limitées, comparativement aux pertes d'azote, il est théoriquement possible d'atteindre des valeurs très élevées d'efficacité d'utilisation du phosphore dans les systèmes agricoles, mais ceci nécessite un parfait recyclage du phosphore des déjections animales et de celui des coproduits animaux.
Radiosurgery and fractionated stereotactic body radiotherapy for patients with lung oligometastases
Authors: Kalinauskaite Goda , Tinhofer Ingeborg , Kufeld Marcus , Kluge Anne Kathrin , Grün Arne , Budach Volker , Senger Carolin , Stromberger Carmen 
Published: May 2020

Abstract
Background: Patients with oligometastatic disease can potentially be cured by using an ablative therapy for all active lesions. Stereotactic body radiotherapy (SBRT) is a non-invasive treatment option that lately proved to be as effective and safe as surgery in treating lung metastases (LM). However, it is not clear which patients benefit most and what are the most suitable fractionation regimens. The aim of this study was to analyze treatment outcomes after single fraction radiosurgery (SFRS) and fractionated SBRT (fSBRT) in patients with lung oligometastases and identify prognostic clinical features for better survival outcomes. Methods: Fifty-two patients with 94 LM treated with SFRS or fSBRT between 2010 and 2016 were analyzed. The characteristics of primary tumor, LM, treatment, toxicity profiles and outcomes were assessed. Kaplan-Meier and Cox regression analyses were used for estimation of local control (LC), overall survival (OS) and progression-free survival.Results: Ninety-four LM in 52 patients were treated using SFRS/fSBRT with a median of 2 lesions per patient (range: 1–5). The median planning target volume (PTV)-encompassing dose for SFRS was 24 Gy (range: 17-26) compared to 45 Gy (range: 20-60) in 2-12 fractions in fSBRT. The median follow-up time was 21 months (range: 3-68). LC rates at 1 and 2 years for SFSR vs. fSBRT were 89% and 83% vs. 75% and 59%, respectively (p=0.026). LM treated with SFSR were significantly smaller (p=0.001). The 1 and 2-year OS rates for all patients were 84% and 71%, respectively. In univariate analysis treatment with SFRS, an interval of ≥ 12 months between diagnosis of LM and treatment, non-colorectal cancer histology and BED <100 Gy were significantly associated with better LC. However, none of these parameters remained significant in the multivariate Cox regression model. OS was significantly better in patients with negative lymph nodes (N0), Karnofsky performance status (KPS) >70% and time to first metastasis ≥12 months. There was no grade 3 acute or late toxicity. Conclusions: Longer time to first metastasis, good KPS and N0 predicted better OS. Good LC and low toxicity rates were achieved after short SBRT schedules.
Transcriptome analysis provides insights into the non-methylated lignin synthesis in Paphiopedilum armeniacum seed
Authors: Fang Lin , Xu Xin , Li Ji , Zheng Feng , Li Mingzhi , Yan Jingwei , Li Yuan , Zhang Xinhua , Li Lin , Ma Guohua , Zhang Aying , Lv Fubin , Wu Kunlin , Zeng Songjun 
Published: May 2020

Abstract
Backgrounds: Paphiopedilum is an important genus of orchid family (Orchidaceae) with high horticultural value. The wild populations are under the threat of extinction because of over collection and habitat destruction. Mature seeds of most Paphiopedilum species are difficult to germinate, which severely restricts the germplasm resources protection and commercial production. The germination inhibition factors are largely unknown.Results: In this study, we found large amounts of non-methylated lignin were accumulated during seed maturation of Paphiopedilum armeniacum (P. armeniacum), which negatively correlates with the germination rate. We then further compared the transcriptome profiles of P. armeniacum seed at different development stages to explore molecular clues for the non-methylated lignin synthesis. KEGG enrichment analysis showed that a large number of genes associated with phenylpropanoid biosynthesis and phenylalanine metabolism as the seed maturation were differentially expressed. Several key genes in the lignin biosynthetic pathways displayed different expression patterns during the lignification process. PAL, 4CL, HCT and CSE were up-regulated to accelerate the C and H lignin accumulation. The expression of CCoAOMT, F5H and COMT were maintained at a low level or down-regulated to inhibit the conversion to the typical G and S lignin. Quantitative real-time RT-PCR analysis confirmed the altered expression levels of these genes among seeds and vegetative tissues. Conclusions: This work demonstrated the plasticity of natural lignin polymer assembly in seed, and provided a better understanding of the molecular mechanism of seed-specific lignification process.
Novel mutations of the SRF gene in Chinese sporadic conotruncal heart defect patients
Authors: Mengmeng Xu , Yuejuan Xu , Sun Chen , Yanan Lu , Fen Li , Kun Sun 
Published: May 2020

Abstract
Background: Conotruncal heart defects (CTDs) are a group of congenital heart malformations that cause anomalies of cardiac outflow tracts. In the past few decades, many genes related to CTDs have been reported. Serum response factor (SRF) is a ubiquitous nuclear protein that acts as transcription factor, and SRF was found to be a critical factor in heart development and to be strongly expressed in the myocardium of the developing mouse and chicken hearts. The targeted inactivation of SRF during heart development leads to embryonic lethality and myocardial defects in mice. Methods: To illustrate the relationship between SRF and human heart defects, we screened SRF mutations in 527 CTD patients, a cross sectional study. DNA was extracted from peripheral blood target sequencing. The mutations of SRF were detected and validated by Sanger sequencing. The affection of the mutations on wild-type protein was analyzed by in silico softwares. Western blot and real time PCR were used to analyze the changes of the expression of the mutant mRNA and protein. In addition, we carried out dual luciferase reporter assay to explore the transcriptional activity of the mutant SRF. Results: Among the target sequencing results of 527 patients, two novel mutations (Mut1: c.821A>G p.G274D , the adenine(A) was mutated to guanine(G) at position 821 of the SRF gene coding sequences (CDS), lead to the Glycine(G) mutated to Asparticacid(D) at position 274 of the SRF protein amino acid sequences; Mut2: c.880G>T p.G294C , the guanine(G) was mutated to thymine (T) at position 880 of the SRF CDS, lead to the Glycine(G) mutated to Cysteine (C) at position 294 of the SRF protein amino acid sequences.) of SRF (NM_003131.2) were identified. Western blotting and RT-PCR showed that there were no obvious differences between the protein expression and mRNA transcription of mutants and wild-type SRF. Dual luciferase reporter assay showed that both SRF mutants (G274D and G294C) impaired SRF transcriptional activity at the SRF promoter and atrial natriuretic factor ( ANF ) promoter ( p <0.05), additionally, the mutants displayed reduced synergism with GATA4. Conclusion: These results suggest that SRF-p.G274D and SRF-p.G294C may have potential pathogenic effects.
Effect of Two Major Health Reforms on Health Care Cost and Utilization in Fars Province of Iran: Family Physician Program and Health Transformation Plan
Authors: Bayati Mohsen , Keshavarz Khosro , Lotfi Farhad , KebriaeeZadeh Abbas , Barati Omid , Zareian Shahram , Amiri Akbar , Delavari Sajad 
Published: May 2020

Abstract
Background: Family physician program (FPP) and health transformation plan (HTP) are two major reforms that have been implemented in Iran's health system in recent. The present study was aimed at evaluating the impact of these two reforms on the level of service utilization and cost of health care services. Methods: This longitudinal study was conducted on people insured by social security organization in Fars province during 2009-2016. The data on the utilization of services and costs of general practitioner visits, specialist visits, medications, imaging, laboratory tests, and hospitalization were collected. Interrupted time series analysis was used to analyze the effect of the two mentioned reforms. Results: FPP resulted in a significant reduction in the number of specialist visits, imaging, and laboratory tests in the short term, and in the number of radiology services, laboratory tests, and hospitalization in the long term. In contrast, HTP significantly increased the utilization of radiology services and laboratory tests both in the short term and long term. Concerning the costs, FPP resulted in a reduction in costs in short and long term except general practitioners' and specialist visit, and medication in long term. However, HTP resulted in an increase in health care costs in both of the studied time periods. Conclusions: FPP has been successful in rationalizing the utilization of services. On the other hand, HTP has improved people’s access to services by increasing the utilization; but it has increased health care costs. Therefore, policymakers must adopt an agenda to revise and re-design the plan.
Radial peripapillary capillary density in superior segmental optic hypoplasia measured with OCT angiography.
Authors: Abe Maiko , Omodaka Kazuko , Kikawa Tsutomu , Nakazawa Toru 
Published: May 2020

Abstract
Background: To investigate the diagnostic power of radial peripapillary capillary (RPC) density, measured with optical coherence tomography angiography (OCT-A), in patients with superior segmental optic hypoplasia (SSOH). Methods: Forty subjects with SSOH and 40 age- and axial length-matched control subjects were retrospectively registered for this study. SSOH was defined as intraocular pressure less than 21 mmHg with the presence of two of the following: superior rim thinning, superior entrance of the central retinal artery, scleral halo, and pale optic disc; as well as non-progressive visual field loss. RPC density was measured with swept-source OCT-A (Triton, Topcon) overall, in the quadrants, and in the 12 clock-wise sectors. Changes in RPC density were also compared in SSOH patients and age-matched patients with mild- or moderate-stage of glaucoma. RPC density was compared in pairs of groups with Welch’s t-test. Diagnostic power was assessed with the area under the receiver operating characteristics curve (AUC). Results: Overall cpRNFLT was significantly different in the normal (106.7 ± 9.5 μm) and SSOH (77.2 ± 13.7 μm, p < 0.001) subjects. RPC density overall and in the superior, nasal, and inferior quadrants was significantly lower in the SSOH group (all, p < 0.001), but not in the temporal (p = 0.756) quadrant. The diagnostic power of RPC density was highest in the superior quadrant (AUC = 0.928) and the 1 o’clock sector (0.896). Comparing the SSOH and glaucoma patients showed that there were no significant differences in RPC density either overall (p=0.391) or in the superior quadrant (p = 0.268), while RPC density was significantly higher in the inferior (p = 0.005) and temporal quadrants (p < 0.001) and lower in the nasal quadrant (p = 0.029). Conclusions: Low RPC density was found in the three non-temporal quadrants of the optic nerve head in SSOH patients, in comparison to normal subjects. Regionally, RPC density in SSOH was lower in the nasal quadrant and higher in the inferior and temporal quadrants in comparison to glaucoma patients. Measuring RPC density with OCT-A may help the diagnosis of SSOH and may improve the management of glaucoma.
Assessing the determinants of Ebola Virus Disease Transmission in Baka Community of the Tropical Rainforest of Cameroon
Authors: Wirsiy Frankline Sevidzem , Bock Alphonse Um , Akoachere Jane-Francis Kihla Tatah 
Published: May 2020

AbstractBackground: Ebola virus disease (EVD) is a severe, often fatal illness in humans and nonhuman primates caused by the Ebola virus. Treatment and vaccine are under development, hence prevention is paramount. Design of effective prevention interventions requires an understanding of the factors that expose communities at risk. It was based on this that we investigated the Baka community of Abong-Mbang Health District in tropical rain forest of Cameroon. Methods : A cross-sectional study was conducted with participants randomly selected from 13 villages in Abong-Mbang by multi-stage cluster sampling. A questionnaire was administered to them to collect demographic information, data on knowledge of EVD, their feeding and health-seeking behaviour. Data was analyzed using the chi-square test. Knowledge of EVD was assessed using an 8 item Morisky Scale. An adapted Threat Capability Basic Risk Assessment Guide was used to determine their risk of exposure to infection. Results: A total of 510 participants, most of whom were hunters (31.4%), farmers (29.8%), and had primary education (62.7%), were included in this study. Although 83.3% participants had heard of EVD, most (71%) did not know its cause. Their source of information was mainly informal discussions in the community (49%). Misconceptions were identified with regards to knowledge on the cause and mode of transmission. Only 43.1% accepted EVD could be transmitted from human-to-human. Generally, participants’ knowledge of EVD was poor. Demographic factors such as level of education, occupation and ethnic group significantly affected knowledge of EVD. The majority of participants were at a very high risk of exposure to infection as they consumed various forms of bush meat and were involved in other risky practices such as scarification and touching of corpses. Although over half of participants seek medical care, most of them preferred traditional medicine. Socio-cultural and service-related factors were deterrent factors to medical care. Conclusion: Participants generally had poor knowledge of EVD and were at high risk of to infection. We recommend rigorous sensitization campaigns in study area to educate the population on EVD and clarify the misconceptions identified. EVD surveillance is recommended particularly as outbreaks have often been reported in the Congo Basin.