bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating effectiveness of screening house eaves as an intervention for integrated vector management for malaria control in Nyabondo, Western Kenya.
Authors: Ng'ang'a Peter Njoroge , Okoyo Collins , Mbogo Charles , Mutero Clifford Maina 
Published: December 2019

Abstract
BackgroundMosquito-proofing of houses with appropriate screens fixed at potential mosquito entry points is gaining greater recognition as a practical intervention for reducing malaria transmission indoors. The study aimed at evaluating the effectiveness of house eaves screening in preventing mosquito entry and malaria prevalence in Nyabondo, western Kenya. Methods160 houses were selected for the study, with half of them randomly chosen for screening at the eaves with fibre-glass coated wire mesh (experimental group) and the other half left without screening (control group). Randomization was carried out by use of computer-generated list, in permuted blocks of ten houses and 16 village blocks in the study site, with treatments in the ratio of 1:1. Cross-sectional baseline entomological and malaria parasitological data were collected before house eave screening. After the baseline period, series of sampling of indoor adult mosquitoes were conducted once a month in each village using CDC light traps. Three cross-sectional malaria parasitological surveys were also conducted at three month intervals after installation of the screens. The primary outcome measures were indoor Anopheles mosquito density and malaria parasite prevalence. ResultsA total of 15,286 mosquitoes were collected over the two years period using CDC light trap in 160 houses distributed over 16 study villages (mean = 4.35, SD = 11.48). Of all mosquitoes collected, 2,872 were anophelines (2,869 An. gambiae s.l., 1 An. funestus and 2 other anopheles). Overall, among An. gambiae collected, 92.6% were non-blood fed, 3.57% were blood fed and the remaining 0.47% were composed of gravid and half gravid females. Overall more mosquitoes were collected in the control than experimental arms of the study. Results from four cross-sectional prevalence surveys showed that screened houses recorded relatively low malaria prevalence rates compared to the control houses. Overall, malaria prevalence was 5.6% (95%CI: 4.2-7.5) N=1,918, with baseline survey recording 6.1% prevalence (95%CI: 3.9-9.4), n=481 and third follow-up survey recording 3.6% prevalence (95%CI: 2.0-6.8) n=494. At all the three follow-up survey points, house screening significantly reduced the malaria prevalence by 100% (p<0.001), 63.6% (p=0.026), and 100% (p<0.001) for first, second and third follow-ups surveys respectively. The house screening significantly reduced malaria prevalence by 54% (OR = 0.46, 95%CI: 0.24-0.87, p = 0.017). Conclusions﻿The study demonstrated that house eave screening has potential to reduce indoor vector densities and malaria transmission in high transmission areas in Kenya.
Effect of cooling vests on physiological and perceptual responses: A systematic review protocol
Authors: Habibi Peymaneh , Heydari Ahad , Moradi Gholamreza , Dehghan Habibollah , Golbabaei Farideh 
Published: December 2019

Abstract
Background: Human in hot environments are exposed to several risks and discomforts which seriously affect their physiological and mental workload. However, they are required to take frequent rest breaks to prevent heat strain when working in hot environments. The main objective of this study is to systematically summarize the literature about the effect of cooling vests on physiological and perceptual responses that might help research and practice in the future.Inclusion criteria: Studies in scientific journals and other databases, focusing on the effect of cooling vests on physiological and perceptual responses will be included.Methods: Three main databases such as PubMed, Scopus, and Web of Science will be searched to find relevant literature on type of cooling vest and effects using subject headings and appropriate MeSH terms. Inclusion and exclusion criteria will be used for screening. Two authors will participate in all of the search stages including preliminary search, screening, quality assessment, data extraction, and data synthesis. We will limit our search to articles published in a peer review journal between 2000 and 2019. The protocol has been written according to PRISMA-P checklist. Three main databases such as PubMed, Scopus, and Web of Science will be searched to find relevant literature on type of cooling vest and effects using subject headings and appropriate MeSH terms. Inclusion and exclusion criteria will be used for screening. Two authors will participate in all of the search stages including preliminary search, screening, quality assessment, data extraction, and data synthesis. We will limit our search to articles published in a peer review journal between 2000 and 2019. The protocol has been written according to PRISMA-P checklist.Objective: The aim of this systematic review is to investigate and compare the effect of different types of cooling vests on physiological and perceptual responses in order to choose the best one according to affecting factors.PROSPERO Registration Number: CRD42019140820
Psychosocial contributors to Internet and social media addiction among adult women
Authors: Rachubińska Kamila , Cybulska Anna , Owczarek Aleksander , Stanisławska Marzanna , Grochans Elżbieta 
Published: December 2019

Abstract
1) Purpose: When speaking of behavioral addictions (especially to the Internet and social media), it is emphasized that is not the environment that is the main contributor to addiction, but rather certain behaviors and personality traits. The aim of this study was to assess the level of Internet and social media addiction on the example of Facebook with regard to psychological and social factors. 2) Methods: This survey-based study involved a group of women representative of the female population in the West Pomeranian Voivodeship, Poland (N = 556). Research instruments were a self-developed questionnaire concerning sociodemographic data, the De Jong Gierveld Loneliness Scale, the Beck Depression Inventory, the Internet Addiction Test, and the Bergen Facebook Addiction Scale. 3) Results: Age, depressive symptoms, loneliness were the variable contributing to Internet and Facebook addiction among the studied. Available studies confirm the results of own research. 4) Conclusions: Depressive symptoms, and dependence on the Internet and Facebook were more common among single women. In the employed women we only observed higher levels of Internet and Facebook addiction. The level of dependence on the Internet and Facebook was higher among younger women. Loneliness correlated with Internet and Facebook addiction, and more severe depressive symptoms entailed higher levels of Internet and Facebook addiction.
Study On the Effectiveness and Safety of Foldable Capsular Vitreous Body Implantation
Authors: Zhang Xiangyang , Tian Xuemin , Zhang Baike , Guo Lisa , Li Xiaodan , Jia Yong 
Published: December 2019

Abstract
Background: Foldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment. The aim of this study was to evaluate the efficacy and safety of the implantation of foldable capsular vitreous body in 1-year follow-up. Methods: A retrospective analysis was conducted for 20 patients with severe ocular trauma or silicone oil (SO) dependent eyes underwent vitrectomy and FCVB implantation in a 1-year follow-up. All treated eyes were peformed clinical examinations involved the visual acuity (VA) examination, Goldmann applanation tonometer, noncontact specular microscopy, fundus photography, B-Scan examination and optical coherence tomography (OCT). The groups were compared with t-test and the McNemar - Bowker test. Results: In 1-year follow-up, 20 eyes were evaluated in the study. FCVB well supported the vitreous retina in all treated eyes, and 6 treated eyes achieved retinal reattachment 12 months after FCVB implantation. There were no significant differences in VA before and after FCVB implantation (P = 1.000). In addition, the postoperative IOP markedly elevated from the preoperative IOP of 12.90 ± 7.06 mmHg to 15.15 ± 3.36 mmHg (P = 0.000017). The intraocular pressure (IOP) of 10 eyes maintained at a normal level after surgeries. The other 10 eyes showed slightly lower IOP within the acceptable level. Though two patients developed keratopathy and ocular inflammation respectively, other treated eyes were symmetric with fellow eyes showing satisfactory appearance. Moreover, there was no SO emulsification or leakage happened in the observation.Conclusions: FCVB implantation was an effective and safe treatment in the eyes with severe retinal detachment. Keywords: Foldable Capsular Vitreous Body; Efficacy; Safety; Retinal detachment
The effect of gestational diabetes mellitus on sufentanil consumption after cesarean section: A prospective cohort study
Authors: yang chen , Geng WeiLian , Hu Jianying , Huang Shaoqiang 
Published: December 2019

Abstract
Background: Previous studies have shown that patients with long-term diabetes require more opioids after surgery than patients without diabetes. Gestational diabetes mellitus (GDM) normally only lasts for a brief period; nevertheless, its effect on sufentanil consumption after cesarean section is unknown. Methods: This prospective cohort study included two groups: a GDM group (n=32) and a matched non-GDM (NGDM) group (n=32). All patients underwent routine combined spinal-epidural anesthesia for cesarean delivery. Sufentanil consumption through an intravenous patient-controlled analgesia (PCA) pump, the frequency of PCA requests, and visual analog scale (VAS) scores 6 and 24 hours after surgery were compared between groups. Results: Sufentanil consumption (µg) 6 hours after surgery was higher in the GDM group than in the NGDM group (24.0±6.6 vs 20.1±5.7, P=0.023). PCA was used more frequently 6 and 24 hours after surgery by the GDM group than by the NGDM group (1[0-2] vs 0[0-1], P=0.001; 6[4-8] vs 3[1-5], P=0.001, respectively). The VAS score during activity 24 hours after surgery was higher in the GDM group than in the NGDM group (5[5-6] vs 5[4-5], respectively, P=0.03). Conclusion: Pregnant women with GDM require more opioids during the immediate postoperative period after cesarean section than those without GDM.
Water, sanitation, and hygiene risk factors of acute diarrhea among children under five years in the Gaza Strip
Authors: Abuzerr Samer , Nasseri Simin , Yunesian Masud , Hadi Mahdi , Zinszer Kate , Mahvi Amir Hossein , Nabizadeh Ramin , Abu Mustafa Ayman , Mohammed Shimels Hussien 
Published: December 2019

Abstract
This cross-sectional community household-based study aims to evaluate the water, sanitation, and hygiene facilities in the Gaza Strip and to investigate their associations with the occurrence of acute diarrhea among children under five years. A survey using a structured questionnaire was conducted on 1,857 households with an child under five years from August 2017 to June 2018. About 69.7% of heads of households reported a diarrheal episode among their children during the two months preceding the survey. Multivariable logistic regression showed that sewage water observed around the households was associated with an increased risk of acute diarrhea (AOR = 2.45; P &lt; 0.001; 95% CI: 1.83–3.27). Nevertheless, the allocation of a special water tank for desalinated drinking water at home (AOR = 0.3; P = 0.02; 95% CI: 0.1–0.8), the connection of households to a closed sewerage system (AOR = 0.56; P &lt; 0.001; 95% CI: 0.43–0.73), and handwashing practices before and after eating (AOR = 0.42; P = 0.003; 95% CI: 0.24–0.74 and AOR = 0.50; P = 0.03; 95% CI: 0.26–0.94, respectively), as well as using desalinated water sources for drinking purposes, were inversely associated with the incidence of acute diarrhea among children under five. Further improvements in the existing sewerage system and the intensification of sanitation and hygiene promotion programs at the household levels may reduce the risk of acute diarrhea among children under five years in the Gaza Strip.
Hypodopaminergia and “Precision Behavioral Management” (PBM): It is a Generational Family Affair
Authors: Fried Lyle , Modestino Edward J. , Siwicki David , Lott Lisa , Thanos Panayotis K. , Baron David , Badgaiyan Rajendra D. , Ponce Jessica V. , Giordano James , Downs William B. , Gondré-Lewis Marjorie C. , Bruce Steinberg , Braverman Eric R. , Boyett Brent , Blum Kenneth 
Published: December 2019

Background/Aims:This case series presents the novel Genetic Addiction Risk Score (GARS®) coupled with a customized pro-dopamine regulator matched to polymorphic reward genes having a hypodopaminergic risk.Methods:The proband is a female with a history of drug abuse and alcoholism. She experienced a car accident under the influence and voluntarily entered treatment. Following an assessment, she was genotyped using the GARS, and started a neuronutrient with a KB220 base indicated by the identified polymorphisms. She began taking it in April 2018 and continues.Results:She had success in recovery from Substance Use Disorder (SUD) and improvement in socialization, family, economic status, well-being, and attenuation of Major Depression. She tested negative over the first two months in treatment and a recent screening. After approximately two months, her parents also decided to take the GARS and started taking the recommended variants. The proband’s father (a binge drinker) and mother (no SUD) both showed improvement in various behavioral issues. Finally, the proband’s biological children were also GARS tested, showing a high risk for SUD.Conclusions:This three-generation case series represents an example of the impact of genetic information coupled with an appropriate DNA guided “Pro-Dopamine Regulator” in recovery and enhancement of life.
The Relevance of Single-nucleotide Polymorphism +62 G>A to the Expression of Resistin Gene Affecting Serum Resistin Levels in Metabolic Syndrome in the Egyptian Population
Authors: Ibrahim Sherine M. , Bastawy Afaf A. 
Published: December 2019

Background:
Metabolic Syndrome (MS) is a clinical condition consisting of risk factors associated
with type two diabetes and developing cardiovascular disease. It has been suggested that resistin
is a linkage between obesity, inflammation and type two diabetes. This study aims to investigate
whether Resistin Gene (RETN) polymorphism (+62G>A) is linked to MS and resistin levels among
the Egyptian population.

Methods:
This study was performed with 310 Egyptian volunteers: 160 MS subjects and 150 controls.
Anthropometric parameters and biochemical variables were determined. The RETN +62G>A polymorphism
was genotyped by PCR-RFLP technique.

Results:
The resistin levels of the MS group were significantly higher than those of the control group.
Resistin levels were positively correlated with anthropometric parameters and liver biomarkers in the
MS group. According to RETN +62G>A polymorphism, carriers with the A allele (GA/AA) had significantly
increased resistin levels than subjects with the GG genotype, consequently, the RETN +62G
>A polymorphism was found to be related to MS, biochemical parameters and anthropometric variables.

Conclusions:
These findings propose that the RETN +62G>A polymorphism has a great impact on the
circulating resistin concentrations, and that resistin levels are strongly related to MS. Therefore, this
RETN polymorphism is related to the risk of the prevalence of MS in the Egyptians.
Facile Synthesis of Naphtha-quinoxaline Derivatives from β-lapachone Using Graphene Oxide as Catalyst
Authors: Vyas Pooja , Wadhwani Barkha Darra , Rao Ravindra Singh , Khandelwal Poonam 
Published: December 2019

Objective:
To develop efficient method for the synthesis of naphtha-quinoxaline derivatives via the
reaction of β-lapachone with various 1,2-diamines.

Methods:
A mixture of β-lapachone (1mmol), 1,2-diamine (1mmol) and graphene oxide (20mg) in methanol
(3mL) was heated at 60°C, under constant stirring for appropriate time. After completion of the reaction, the
catalyst was filtered off, washed with ethyl acetate (3x3mL) and the combined filtrate was washed with H2O,
dried (anhy. Na2SO4) and concentrated under vacuum. The residue was chromatographed over a column of
silica gel eluting with a mixture of hexane and ethyl acetate in different ratios, to afford the desired product. All
synthesized compounds were assigned with the help of analytical and 1H, 13C NMR, IR, and mass spectral
studies.

Results:
To establish the catalytic role of GO in the synthesis of naphtha-quinoxaline derivatives, the reaction
of β-lapachone with 3,4-diaminotoluene was selected as a model reaction. The catalytic activity of graphene
oxide in comparison with other catalysts like acidic resin amberlyst-15 and solid acid catalyst like
montmorillonite K-10 were studied. The reaction was also observed in various solvents such as water,
acetonitrile, toluene, dichloromethane, ethanol and 1,4-dioxane using GO as a catalyst. Excellent yields were
obtained at 60°C in methanol. The efficacy of the present protocol was investigated by the reaction of β-
lapachone with other 1,2-diamines.

Conclusion:
An attractive green metal free carbocatalyst Graphene Oxide (GO) has been successfully utilized
for the expedient synthesis of naphtha-quinoxaline derivatives. GO showed high catalytic activity which is
attested by the desired products being produced in shorter time. The main advantage of this method is the
reusability of the catalyst which makes the procedure sustainable.
Antiviral Action of Curcumin Encapsulated in Nanoemulsion against Four Serotypes of Dengue Virus
Authors: Nabila Najwa , Suada Nadia Khansa , Denis Dionisius , Yohan Benediktus , Adi Annis Catur , Veterini Anna Surgean , Anindya Atsarina Larasati , Sasmono R. Tedjo , Rachmawati Heni 
Published: December 2019

Background:
Curcumin has been used as a traditional medicine showing antiinflammatory,
antimicrobial, and antiviral properties. Despite the promising potentials,
curcumin-based drug development is hindered due to its poor solubility and cell uptake.

Objective:
This study aims to produce curcumin nanoemulsion (nanocurcumin) and evaluate
its physical characteristics and in vitro cell cytotoxicity and antiviral activity against
dengue virus (DENV).

Method:
Nanocurcumin was generated by self-nanoemulsion technique. Cytotoxicity was
determined using MTT assay in A549 cell line. Anti-DENV properties were determined by
calculation of inhibitory concentration 50 (IC50) and plaque assay.

Results:
The resulting nanoemulsion showed uniform droplet size distribution with the average
droplet size of 40.85 ± 0.919 nm. Nanocurcumin exhibited higher cell cytotoxicity
compared to curcumin solution and may be explained by better cell uptake. Nanocurcumin
treatment suppressed DENV growth, although no significant difference observed compared
to the curcumin solution counterpart. Greater virus reduction was observed for DENV-1
and DENV-2.

Conclusion:
The synthesis of nanocurcumin improved curcumin physicochemical properties
with potential as antiviral against DENV.
An Energy Efficient Routing Approach to Enhance Coverage for Application-Specific Wireless Sensor Networks Using Genetic Algorithm
Authors: Sohal Amandeep K. , Sharma Ajay K. , Sood Neetu 
Published: December 2019

Background:
An information gathering is a typical and important task in agriculture
monitoring and military surveillance. In these applications, minimization of energy consumption
and maximization of network lifetime have prime importance for green computing. As wireless sensor
networks comprise of a large number of sensors with limited battery power and deployed at remote
geographical locations for monitoring physical events, therefore it is imperative to have minimum
consumption of energy during network coverage. The WSNs help in accurate monitoring of
remote environment by collecting data intelligently from the individual sensors.

Objective:
The paper is motivated from green computing aspect of wireless sensor network and an
Energy-efficient Weight-based Coverage Enhancing protocol using Genetic Algorithm (WCEGA) is
presented. The WCEGA is designed to achieve continuously monitoring of remote areas for a longer
time with least power consumption.

Methods:
The cluster-based algorithm consists two phases: cluster formation and data transmission.
In cluster formation, selection of cluster heads and cluster members areas based on energy and coverage
efficient parameters. The governing parameters are residual energy, overlapping degree, node
density and neighbor’s degree. The data transmission between CHs and sink is based on well-known
evolution search algorithm i.e. Genetic Algorithm.

Results:
The results of WCEGA are compared with other established protocols and shows significant
improvement of full coverage and lifetime approximately 40% and 45% respectively.

Conclusion:
This paper proposes an evolutionary method to improve an energy-efficient clustering
protocol for longer full coverage.
Implementasi Sistem â€œKeremanâ€ dan Pertanian Terpadu pada Penggemukan Sapi Potong di Dua Kelompok Ternak di Kabupaten Sokaraja
Authors: Anggraeni Ayu Septi , Istiqomah Lusty , Damayanti Ema 
Published: December 2019

Sistem Kereman dan pertanian terpadu diaplikasikan di dua kelompok ternak yaitu peternakan Berkah dan Peternakan Pondok Pesantren Roudlotul Huda untuk meningkatkan manajemen penggemukan dan meningkatkan produktivitas ternak. Implementasi Sistem Pertanian Terpadu dimulai dengan konstruksi perbaikan kandang, implementasi alih teknologi dalam manajemen penggemukan dan teknologi pakan meliputi: proses produksi silase dan amoniasi jerami padi sebagai alternatif hijauan pakan bagi ternak dengan menggunakan limbah pertanian; suplementasi dedak padi terfermentasi sebagai aditif pakan untuk meningkatkan citarasa pakan serta pengolahan limbah kotoran menjadi pupuk organik, dan sistem irigasi tetes pada pertanian. Transfer teknologi dilakukan dengan memberikan bimbingan teknis bagi Petani. Konsep keberlanjutan adalah elemen penting dalam pengembangan sistem pertanian terpadu karena dengan produk (output) dari satu sistem menjadi input untuk sistem lain. Manajemen yang berbeda di kedua UKM terutama dalam manajemen pemberian pakan menghasilkan perbedaan bobot badan pada sapi potong. Dampak dari kegiatan ini di dua UKM adalah efisiensi produksi yang lebih tinggi yang direfleksikan pada nilai pertambahan bobot badan harian (PBBH) yang dicapai dalam periode lebih cepat dari sebelumnya. Manajemen pakan, pengalaman dalam penggemukan sapi potong akan berpengaruh pada produktivitas ternak. Hal ini ditunjukkan pada kenaikan PBBH yang lebih tinggi di UKM yang menerapkan manajemen pakan yang lebih baik.Â Â