bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co-administration of vitamin E and atorvastatin improves insulin sensitivity via peroxisome proliferator-activated receptor γ in hyperlipidemic type 2 diabetic patients: a randomized double-blinded clinical trial
Authors: Tabaei Banafsheh Sadat , Rahimian Aliasghar , Rostamkhani Hadi , Mousavi Neda , Mellati Ali Awsat , Jameshorani Maryam 
Published: April 2020

Abstract
Background: Contrary to the reports about the useful effects of atorvastatin on blood lipids and insulin sensitivity by up-regulation of peroxisome proliferative-activated receptor gamma (PPAR-γ) expression, to our knowledge, there is inconclusive results about vitamin E. Also, there is no study to assess co-administration of vitamin E and atorvastatin on PPAR-γ mRNA expression, insulin sensitivity and lipid profile in diabetic patients. We compared this effect in hyperlipidemic subjects with type 2 diabetes mellitus (T2DM). Methods: At the present randomized clinical trial (RCT), 30 T2DM women with hyperlipidemia were categorized into the treated group with 20 mg atorvastatin plus 400 IU vitamin E supplement (n = 15) or atorvastatin plus placebo (n = 15) per day for 12 weeks. Anthropometric and biochemical measures were done at the baseline and after the 12-week intervention. PPAR-γ mRNA expression was measured in the peripheral blood mononuclear cells (PBMCs) of all patients. Results: After adjusting for the baseline measures, vitamin E resulted in significant improvements in insulin sensitivity in terms of HOMA-IR (-1.01±0.52 vs. -2.56 ± 0.54, P = 0.04) and serum insulin (-0.55±0.35 vs. -6.5 ± 1.3, P < 0.001), compared with the atorvastatin plus placebo. Adjusted for the baseline variables, compared with the atorvastatin plus placebo, vitamin E supplementation could up-regulate PPAR-γ mRNA expression (OR=5.4, 95% CI=0.8-36.9, P=0.04) in PBMC of T2DM women. Conclusions: Vitamin E supplementation along with atorvastatin may improve insulin sensitivity through up-regulation of PPAR-γ gene. More RCTs are needed to reach conclusive results. Trial registration: The present study is registered under ClinicalTrials.gov Identifier no. IRCT20170918036256N1.
The Oxidative Stress Pathway May be an Important Pathway Leading to The Recurrence of Ewing Sarcoma —— Based On Weighted Gene Co-Expression Network Analysis
Authors: Li Jianfeng , Hu Shaoyu , Hao Song , Huang Shengjia , Qin Yi , Wang Jianjun 
Published: April 2020

Abstract
Background The role of gene and pathway in recurrence of Ewing sarcoma (ES) was not clear. Thus, we investigated the biological role and underlying mechanism of gene and pathway in recurrence of ES. Methods Data sets of patients with ES were collected from the GEO database. We used dataset GSE63155 and GSE63156 to construct co-expression networks by weighted gene co-expression network analysis (WGCNA). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed by Database for Annotation, Visualization and Integrated Discovery (DAVID). Results We can find that genes with significant interactions in the genes of the recurrence group include SRSF11, TRIM39, SOCS3,NUPL2,COPS5. They work primarily through the oxidative stress pathway. Conclusion Through our research, for the first time found that ES by SRSF11 TRIM39, SOCS3, NUPL2, COPS5 interaction, activation of phosphorylation of bone and oxidative stress is affecting tumor recurrence.
The rice annexin gene OsAnn5 is a positive regulator of cold stress tolerance at the seedling stage
Authors: shen chunxiu , Que Zhiqun , Lu Qineng , Liu Tao , Li Shengqiang , Zou Jie , Chen Gang 
Published: April 2020

Abstract
Annexins exist widely in plants as multigene families and play critical roles in stress responses and a range of cellular processes. In this study, we report on the cloning and functional characterization of the rice annexin gene OsAnn5. We found that the expression of OsAnn5 was induced by cold stress treatment at the seedling stage of rice. GUS staining assay indicated that the expression of OsAnn5 was non tissue-specific and was detected in almost all rice tissues. Subcellular localization indicated that OsAnn5-GFP (green fluorescent protein) signals were found in the endoplasmic reticulum apparatus. Compared with wild type rice, overexpression of OsAnn5 significantly increased survival rates at the seedling stage under cold stress, while knocking out OsAnn5 using the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR associated proteins) mediated genome editing resulted in sensitivity to cold treatments. These results indicate that OsAnn5 is a positive regulator of cold stress tolerance at the seedling stage.
Clinical course and characteristics of Corona Virus Disease 2019 in Xiaoshan, Hangzhou: A Retrospective study
Authors: Lai Fenhua , Zheng Yongtao , Jia Hexiang , Wang Fuliang , Sun Xiangjue , Yang Dongbo , Xu Miaojian , Xu Diwei , Lu Chao , Ge Bo , Chen Shenglan , Li Biao , Chen Ting , Li Zhibo , Feng Yuanmei 
Published: April 2020

Abstract

Background: The World Health Organization declared the outbreak a public health emergency of international concern (Corona Virus Disease 2019) on January 30th, this study aimed to investigate the epidemiological and clinical characteristics of Corona Virus Disease 2019 in Xiaoshan, Hangzhou, and evaluate scientific basis for disease control and prevention. Methods: A total of 30 patients had been admitted to hospital from Jan 22 to Feb 22, 2020, all of them were laboratory confirmed SARS-Cov-2. Demographic, epidemiological, clinical, laboratory data were collected from Hospital information system and Epidemiological investigation reports. All data was performed by descriptive analysis, Chi-square test or non-parametric Mann-Whitney U test, as appropriate. Two sided p value less than 0.05 was considered statistically significant.Results: 30 patients were enrolled, the median age was 44.5 years (IQR 33.8-52.3) and 17 (56.7%) patients were female, 14 (46.7%) patients were native and had no exposure to Hubei Province. At the time of study submission, only one patient had not been discharged and no patients died during the study. The median hospital stay was 16.0 days (IQR 12.5-20.5) and the median course of disease was 20.5 days (IQR 17.0-23.3). The most common symptoms were fever (66.7%), dry cough (26.7%), and pharyngalgia (23.3%) on first admission. Most patients were generally illness or more mild, but 10 (33.3%) patients received oxygen therapy and 14 (46.7%) patients received hormone therapy during their hospitalization. Almost half of patients showed mild lymphocytopenia and 40% patients had elevated concentrations of CRP in the early stages of COVID-19.﻿Conclusions: Among the 30 patients were confirmed with SARA-Cov-2 infection in Xiaoshan, Hangzhou, most of them had clinical presentation of respiratory tract infection, but the median course of disease was more than 2 weeks. Further systematic prospective studies about COVID-19 should be urgently needed.
Novel Biomass Derived from Grape Pomace Waste as an Efficient Nanocatalyst for the Synthesis of Dibenzoxanthene, Tetraketone, bis(indolyl)alkane and Chromene Derivatives and their Antimicrobial Evaluation
Authors: Ghorbani Fatemeh , Pourmousavi Seied Ali , Kiyani Hamzeh 
Published: April 2020

Background:
Sulfonated carbon-based solid acids (CBSAs) have been reported as an efficient solid
acid catalyst for many acid-catalyzed reactions. Furthermore, the use of carbon obtained from biomass waste
has been explored and these materials showed a higher catalytic performance and higher stability compared to
other solid acids.

Objective:
Novel biomass carbon-based solid acids nanoparticles with high catalytic activity in organic
transformation, such as Grape pomace waste-SO3H Nanoparticles (GPW-SO3H NPs), were successfully
synthesized.

Materials and Methods:
Grape pomace waste-SO3H Nanoparticles (GPW-SO3H NPs) were successfully
synthesized. The grape pomace waste was dried in an oven at a temperature of 70°C and crushed to powder
using an electric spice grinder. A mixture of powdered grape pomace waste (1 g) and concentrated sulfuric acid
(>98%, 10 mL) was stirred at room temperature. Then, the resultant mixture was transferred into a 100 mL
sealed Teflon-lined autoclave and kept at 180°C for 12 h. After cooling to room temperature, the resulting
black solid was dried at 100°C in an oven under vacuum and the sulfonic acid-functionalized magnetic
nanoparticles (Fe3O4@C-SO3H) were obtained.

Results and Discussion:
The catalytic activity of GPW-SO3H was assessed through an easy and rapid
protocol developed for the one-pot synthesis of 14-aryl-14-H-dibenzo [a,j]xanthene, arylmethylene [bis(3-
hydroxy-2-cyclohexene-1-one)], bis(indolyl)alkane and 2-amino-4-aryl-7-hydroxy-4H-chromene-3-carbonitrile
derivatives in excellent yields. The advantages of this method include use of waste material for catalyst
synthesis, high yields, mild reaction conditions, uncomplicated work-up procedures, neutral conditions, and
recoverable catalyst.

Conclusion:
We have shown that biomass-derived solid acids, prepared from grape pomace waste, serve as a
non-toxic, inexpensive and a promising eco-friendly and novel carbon-based solid acid nanocatalyst for
organic transformations.
Effective Dye Degradation Using Sol-Gel Synthesized Titania Nanostructures
Authors: Parakkandy Priyanka Karathan , Balakrishna Kagalagodu Manjunthiah , Varghese Thomas 
Published: April 2020

Background:
The organic effluents from industry remain one of the reasons for water
contamination. By the natural degradation process, it is difficult to remove this; hence finding an effective
solution for this is inevitable. TiO2-based materials have received enormous attention in the
area of semiconductor photocatalysis, particularly for the degradation of organic dyes. This work
emphasizes on the degradation of two industrial dyes methylene blue and rhodamine blue by visible
light irradiation of TiO2 based nanoparticles.

Methods:
In the present study, pristine and La3+ and Ce3+ doped nanotitania were synthesized by the
sol-gel method. The samples under investigation were characterized using X-ray diffraction, Transmission
electron microscopy to study the variation of crystallite size and UV-Visible absorption
spectroscopy.

Results:
The increase in crystallite size for the pristine samples calcined at various temperatures confirms
the effect of calcination temperature. Also, the doping reduced the size of the synthesized nanotitania.
Visible light extended absorption spectra have been observed for the calcined samples and
Ce3+ doped nanotitania. The La3+ doped sample showed a blue shift in the absorption confirming
quantum confinement. The photocatalytic activity in the context of degradation of certain industrial
dyes such as methylene blue and rhodamine blue has been investigated for the samples.

Conclusion:
The studies found that nanotitania consisting of mixed anatase-rutile phase exhibits higher
degradation efficiency than that of pure anatase or rutile samples. Besides, photocatalytic dye degradation
has been significantly improved for Ce3+ doped nanotitania compared to the pristine sample.
Menentukan Jumlah Pasokan Komoditas Pangan di Provinsi Riau Berdasarkan Fuzzy Inference System dengan Metode Fuzzy Tsukamoto
Authors: Rahmawati Rahmawati Ama 
Published: April 2020

Food is the primary need of the population in Indonesia. Increased food demand along with the increasing of population growth. Food availability is an aspect to be met by the Indonesia government as an effort to prosper the community. In facts, food availability in a country or a region not always can be met well. Therefore, the government needs to stabilize the level of food availability, one of the efforts is by importing or supplying food from abroad. Food supply planning needs to be done carefully so as not to shut down domestic food production and it was expected to stabilize food security. Planning of the quantity of food commodity supply will be done by taking into account the number of population needs and the number of food production itself. Because the number of food needs and production is very relative and always changing at a certain time, then to determined the amount of food supply will be done with fuzzy inference system. Tsukamoto’s fuzzy method is one of the methods in the fuzzy inference system. So, the result of this research is to find of food commodity supply in Riau Province based on number of food need and number of food production with fuzzy inference system using Tsukamoto's fuzzy method.
Tecendo vidas
Authors: Biehl Paulo Felipe Soares , Costa Cassiane Da 
Published: April 2020

O objetivo desse artigo foi pesquisar saberes e aspectos identitários relativos ao artesanato em lã no pampa brasileiro. Para alcançar esse objetivo, foram realizadas oito entrevistas com artesãos e artesãs do município Santana do Livramento com auxílio de um roteiro de questões. Os artesãos e as artesãs resgatam a trajetória de suas vidas junto a essa paixão de tecer individualmente ou em grupo, de diferentes formas, preservando a rusticidade. Acompanhando as mudanças do mercado, somando os saberes repassados no interior da família e nos cursos, o artesanato em lã e as pessoas que o fazem garantem a vitalidade da identidade territorial do pampa a cada nova peça que produzem, carregada de significados.
Palavras-chave: Artesanato. Cadeia da lã. Saberes. Identidade territorial. Pampa brasileiro.
O Perfil da saúde das mulheres e os motivos que as levam a evitar a gestação
Authors: Berteloni Glauciane Marques de Assis , Cestari Maria Elisa Wotsazek , Sodré Thelma Malagutti 
Published: April 2020

Objetivo: Identificar o perfil da saúde das mulheres usuárias da internet e os motivos que as levaram a evitar a gestação. Métodos: Trata-se de uma pesquisa quantitativa, transversal e descritiva, com coleta de dados por formulário divulgado em rede social on-line. Resultados: Participaram 1071 mulheres, entre 14 e 29 anos, mais de 40% possuíam ensino superior completo, 87,6% eram nuligestas e 40,8% tinham histórico gestacional (MCHO). Os motivos que as levaram a evitar a gestação foram: possuir a quantidade de filhos desejada (34,1%); condições financeiras desfavoráveis (16,2%); desejo de engravidar posteriormente (39,1%); planos de concluir os estudos (25,3%) e não-maternidade (20,6%). Os métodos anticoncepcionais mais utilizados foram o hormonal oral (43,6%) e de barreira (34,5%). Conclusão: O perfil das mulheres da internet colabora para maiores possibilidades de empoderamento e autonomia devido ao acesso à informação. As mulheres continuam em adaptação aos novos modelos de vida, apresentam motivos relevantes para evitar a gestação e utilizam métodos reversíveis para postergar a maternidade. As mulheres devem ter condições de escolha informada em relação ao seu planejamento reprodutivo, para isso, os serviços de saúde devem garantir acesso aos métodos e informações adequadas sobre a contracepção, para prevenção de agravos à saúde da mulher.
Epitome und Erzählung. Die Rekapitulationen am Ende der Odyssee
Authors: Grethlein Jonas 
Published: April 2020

Abstract
The article interprets the two summaries at the end of the Odyssey, namely Odysseus’ narration of his adventures in book 23 and Amphimedon’s account of the events on Ithaca in book 24, as embedded epitomes. The interpretation highlights the complexity of the Odyssey’s ending and explores the hermeneutic and temporal dimensions of epitomizing, which, it is suggested, are closely linked to cognitive processes.
Effect of rearing density on reproduction and embryogenesis of zebrafish Danio rerio (Hamilton, 1922)
Authors: Rabbane Md Golam , Rahman Md Mizanur , Kabir Md Alamgir , Faruque Md Hasan 
Published: April 2020

Effect of rearing density (5, 15, 25, 35 and 45 fish/l2) on reproductive performances such as spawning success, fertilization rate, hatching rate and embryogenesis in terms of per cent survival rate of embryos at cleavage, gastrula, segmentation, pharyngula and hatching were evaluated. Survival, hatching, fertilization rate and per cent survivability of embryos did not differ significantly between the treatments 1, 2 and 3, but showed significant difference (p < 0.05) between 4 and 5. Treatment three (25 fish/l2) had five-folds higher number of successful progeny than treatment one. Results suggest that 25 fish/l2 can be used as optimum rearing density.
Dhaka Univ. J. Biol. Sci. 26(1): 77-82, 2017 (January)
Effects of long term exposure to aluminium stress on the accumulation and distribution of K+, Na+, Ca2+, Mg2+, Fe2+ and Clin rice and chickpea plants
Authors: Samad Rifat , Rashid Parveen , Karmoker JL 
Published: April 2020

Sand culture experiments were undertaken to examine the effect of increasing aluminium levels (50-150 μM) on the mineral nutrients uptake (K+, Na+, Ca2+, Mg2+, Fe2+ and Cl-). Increasing concentrations of Al inhibited the uptake of K+, Ca2+, Mg2+ and Fe2+ but enhanced that of Na+ and Cl- in the root and shoot of rice, and the root, stem and leaves of chickpea. 150 μM Al caused a maximum inhibition of K+ accumulation in the root and shoot of rice ranging from 25.5 to 49.0% and 33 to 55.5%, respectively, from 7 to 28 day of treatment. In the root, stem and leaves of chickpea, 150 μM Al inhibited K+ content by 23.9 to 84.0%, 13.2 to 54.4% and 25.3 to 61.2%, respectively, from 7 to 28 day of application. On the contrary, a dramatic 2.7 to 3.1-folds and 70.8% to 2.3-folds stimulation of Na+ accumulation was recorded in the root of rice and chickpea, respectively, following 100 μM Al treatment from 7 to 28 day of treatment. Different concentrations of aluminium led to a stimulation of Cl- accumulation in different parts of rice and chickpea plants. In rice and chickpea plants, the inhibitory effect of aluminium stress on the accumulation of Ca2+, Mg2+ and Fe2+ was enhanced with the increase in Al concentration from 50 to 150 μM.
Dhaka Univ. J. Biol. Sci. 27(1): 37-48, 2018 (January)
Pathogenic gut microbiota associated with striped catfish, Pangasianodon hypophthalmus cultured in Bangladesh and their antibiotic sensitivity pattern
Authors: Begum Mst Aziza , Punom Nusrat Jahan , Eshik Md Mostavi Enan , Begum Mst Khadiza , Khan Tahsin , Saha Mihir Lal , Rahman Mohammad Shamsur 
Published: April 2020

To identify the gut bacteria of Pangasianodon hypophthalmus (striped catfish; Pangas) using classical and molecular approach was carried out. Total bacterial count (TBC) in the gut of pangas from farm and market samples were found 5.07 ± 1.70 × 106 and 1.40 ± 0.47 × 106 cfu/g, respectively. The gut microbiota of pangas was dominated by members of the Gram-negative genera. Only three isolates (MyF1/1, MyF1/4 and GaW1/2) were found to be Gram-positive among the 16 representative isolates. Using 16S rRNA gene sequencing; Bacillus, Macrococcus, Citrobacter, Aeromonas, Proteus, Klebsiella, Enterobacter, Escherichia and Edwardsiella were found to be associated with the gut of this fish. Among them, Aeromonas was the most dominant genus (5 out of 16). Antibiotic sensitivity pattern reflected that all the isolates were sensitive to gentamycin. Multiple antibiotics resistant isolates were also identified of which MyF3/13 (identified as Citrobacter amalonaticus) was found resistant against seven tested antibiotics. The presence of pathogenic bacteria in fish gut revealed the improper handling practices in fish market and unhygienic condition in the culture sites which might be a reason of fish-borne disease outbreaks. On the other hand, widespread use of various antibiotics in aquaculture without proper awareness may lead to resistance to multiple antibiotics.
Dhaka Univ. J. Biol. Sci. 29(1): 61-73, 2020 (January)
Jungermannia exertifolia Steph. - A new bryophyte record from Bangladesh
Authors: Tabassum Nadra , Begum Momtaz , Rahman M Oliur 
Published: April 2020

A leafy liverwort, Jungermannia exertifolia Steph. (Hepaticae, Jungermanniales,) has been reported from the Adampur Forest of Moulvibazar district as a new species record for Bangladesh. Jungermannia exertifolia is characterized by its flattened leaves and rhizoids arising ventrally all along the stem with alternate leaves, which are obliquely inserted and succubous in arrangement. It grows in the shady habitats of Adampur forest on the surface of the hilly rocks. Detailed taxonomy of the newly reported species along with its photographs is provided.
Dhaka Univ. J. Biol. Sci. 29(1): 133-136, 2020 (January)
Multi-Hazard Vulnerability Assessment of an Urban Area: A Case Study on Ward 34 of Dhaka South City Corporation
Authors: Rahman M Maksudur , Aktar Shamima , Md Ashikuzzaman - 
Published: April 2020

Multi-hazard assessment provides the scope to understand the vulnerability situation of any area based on different hazard context. This study was conducted in one ward of Dhaka city corporation area to examine its multi-hazard vulnerability. Three key potential hazards: fire, earthquake and water-logging were considered to implement the multihazard analysis framework. To perform the analysis entire study area was surveyed and examined applying Geographic Information System in terms of practicing planning rules and regulation of Government of Bangladesh. All the structures of the study area were assessed and categorized into four classes ranging from severe to none according to some vulnerability criteria defined by safety standards. Individual vulnerability analysis was performed to realize the hazard specific vulnerability context. Finally, single processed hazard maps were combined to examine the multi hazard vulnerability of this study area. These findings denote that there are a certain number of structures in very risk position which should receive immediate hazard mitigation measures.
Asiat. Soc. Bangladesh, Sci. 43(2): 181-195, December 2017
Fish Bio-Diversity and Livelihood of Fishers of Dekar Haor in Sunamganj of Bangladesh
Authors: Suravi IN , Islam MS , Begum N , Kashem MA , Munny FJ , Iris F 
Published: April 2020

The study was carried out to assess the present status of fish biodiversity in Dekar haor and livelihood of fishermen living around the haor under Sunamganj district during 12 months from September 2015 to August 2016. Monthly fish samples were collected from the catches of fishermen and identified based on meristic and morphometric characteristics. A total of 51 fish species belonging to 34 genera along with two prawn species under 19 families was found. Among them catfishes were most abundant. The values of Shannon-Weiner diversity (H′), Margalef’s richness (d), Pielou’s evenness indices (J′) and Simpson dominance indices (c) ranged from 3.36-3.78, 6.12-8.40, 0.98- 0.99 and 0.97-0.98, respectively. Livelihood data were collected through direct interview from randomly selected 73 fishermen. Main occupation of fishermen is fishing. There were three age groups such as young (18-35 years), middle (36-45 years) and old group (above 46 years) where young group was mostly involved in fishing. Most of the fishermen (72.61%) were Muslims and 63% were able to sign only followed by others. Annual income of fishermen varied from Tk. 10,000-100,000. Majority of them had low savings with poor housing and sanitation facilities. Maximum fishers are interested to live in unit family owing to low income. Results of this study imply that fish diversity status was not satisfactory. Also livelihood condition of fishers was not so good. Therefore, appropriate measures should be taken to improve the livelihood of fishermen and to protect the bio-diversity of the haor.
Asiat. Soc. Bangladesh, Sci. 43(2): 233-244, December 2017