bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neural and Psychological Predictors of Cognitive Enhancement and Impairment from Neurostimulation
Authors: Yang Li‐Zhuang , Zhang Wei , Wang Wenjuan , Yang Zhiyu , Wang Hongzhi , Deng Zhi‐De , Li Chuanfu , Qiu Bensheng , Zhang Da‐Ren , Kadosh Roi Cohen , Li Hai , Zhang Xiaochu 
Published: January 2020

AbstractModulating the temporoparietal junction (TPJ), especially the right counterpart, shows promises in enhancing social cognitive ability. However, it is ambiguous whether the functional lateralization of TPJ determines people's responsiveness to brain stimulation. Here, this issue is investigated with an individual difference approach. Forty‐five participants attended three sessions of transcranial direct current stimulation (tDCS) experiments and one neuroimaging session. The results support the symmetric mechanism of left and right TPJ stimulation. First, the left and right TPJ stimulation effect are comparable in the group‐level analysis. Second, the individual‐level analysis reveals that a less right‐lateralized TPJ is associated with a higher level of responsiveness. Participants could be classified into positive responders showing cognitive enhancement and negative responders showing cognitive impairment due to stimulation. The positive responders show weaker connectivity between bilateral TPJ and the medial prefrontal cortex, which mediates the prediction of offline responsiveness by the lateralization and the social‐related trait. These findings call for a better characterization and predictive models for whom tDCS should be used for, and highlight the necessity and feasibility of prestimulation screening.
Atomic Scale Origin of Metal Ion Release from Hip Implant Taper Junctions
Authors: Balachandran Shanoob , Zachariah Zita , Fischer Alfons , Mayweg David , Wimmer Markus A. , Raabe Dierk , Herbig Michael 
Published: January 2020

AbstractMillions worldwide suffer from arthritis of the hips, and total hip replacement is a clinically successful treatment for end‐stage arthritis patients. Typical hip implants incorporate a cobalt alloy (Co–Cr–Mo) femoral head fixed on a titanium alloy (Ti‐6Al‐4V) femoral stem via a Morse taper junction. However, fretting and corrosion at this junction can cause release of wear particles and metal ions from the metallic implant, leading to local and systemic toxicity in patients. This study is a multiscale structural‐chemical investigation, ranging from the micrometer down to the atomic scale, of the underlying mechanisms leading to metal ion release from such taper junctions. Correlative transmission electron microscopy and atom probe tomography reveals microstructural and compositional alterations in the subsurface of the titanium alloy subjected to in vitro gross‐slip fretting against the cobalt alloy. Even though the cobalt alloy is comparatively more wear‐resistant, changes in the titanium alloy promote tribocorrosion and subsequent degradation of the cobalt alloy. These observations regarding the concurrent occurrence of electrochemical and tribological phenomena are vital to further improve the design and performance of taper junctions in similar environments.
Progress and Perspective of Ceramic/Polymer Composite Solid Electrolytes for Lithium Batteries
Authors: Li Song , Zhang Shi‐Qi , Shen Lu , Liu Qi , Ma Jia‐Bin , Lv Wei , He Yan‐Bing , Yang Quan‐Hong 
Published: January 2020

AbstractSolid composite electrolytes (SCEs) that combine the advantages of solid polymer electrolytes (SPEs) and inorganic ceramic electrolytes (ICEs) present acceptable ionic conductivity, high mechanical strength, and favorable interfacial contact with electrodes, which greatly improve the electrochemical performance of all‐solid‐state batteries compared to single SPEs and ICEs. However, there are many challenges to overcome before the practical application of SCEs, including the low ionic conductivity less than 10−3 S cm−1 at ambient temperature, poor interfacial stability, and high interfacial resistance, which greatly restrict the room temperature performance. Herein, the advances of SCEs applied in all‐solid‐state lithium batteries are presented, including the Li ion migration mechanism of SCEs, the strategies to enhance the ionic conductivity of SCEs by various morphologies of ICEs, and construction methods of the low resistance and stable interfaces of SCEs with both cathode and anode. Finally, some typical applications of SCEs in lithium batteries are summarized and future development directions are prospected. This work presents how it is quite significant to further enhance the ionic conductivity of SCEs by developing the novel SPEs with the special morphology of ICEs for advanced all‐solid‐state lithium batteries.
Winter cover crops effects on soil properties and sweet corn yield in semi‐arid irrigated systems
Authors: Antosh Eric , Idowu John , Schutte Brian , Lehnhoff Erik 
Published: January 2020

AbstractWinter cover crops (WCCs) can bolster agroecosystem services, including improving soil and crop yields. However, information is lacking about WCCs in irrigated crops in the semiarid climates of the southwestern United States. We chose three WCC species for their ecological attributes: hairy vetch (Vicia villosa, nitrogen fixation), rye (Secale cereale, nutrient sequestration; allelopathy), and mustard (Brassica juncea, biofumigant). Crops were planted in either monoculture or 2‐ and 3‐way combinations to evaluate agroecosystem services. Sweet corn (Zea mays L.) was planted approximately 2 wk after WCC termination. Neither monocultures nor mixtures consistently produced the most biomass, as WCC biomass production differed between site and year. The highest yielding cover crop was vetch (4302 kg ha−1) followed by mustard–vetch (3528 kg ha−1) and rye–vetch (3130 kg ha−1), all within the same site year, and rye (3016 kg ha−1) in another site year. Cover crops generally increased mean weight diameter of soil aggregates (a measure of dry soil aggregation) over time, with values nearly doubling in mustard–vetch and mustard–rye–vetch plots at one site. Wet aggregate stability increased by as much as 18% in mustard and 27% in mustard–vetch plots. Fertilizer requirements decreased compared to fallow plots in the second year in all WCC plots except for rye at one site, and vetch increased sweet corn yield compared to dry fallow plots in 1 yr by an average of 43.1%. These results demonstrate that WCCs can have positive effects on dry aggregate stability and potentially cash crop yield in irrigated, semiarid agroecosystems.
Tatton‐Brown‐Rahman syndrome: Six individuals with novel features
Authors: Balci Tugce B. , Strong Alana , Kalish Jennifer M. , Zackai Elaine , Maris John M. , Reilly Anne , Surrey Lea F. , Wertheim Gerald B. , Marcadier Julien L. , Graham Gail E. , Carter Melissa T. 
Published: January 2020

AbstractTatton‐Brown Rahman syndrome (TBRS) is an overgrowth‐intellectual disability syndrome caused by heterozygous variants inDNMT3A. Seventy‐eight individuals have been reported with a consistent phenotype of somatic overgrowth, mild to moderate intellectual disability, and similar dysmorphisms. We present six individuals with TBRS, including the youngest individual thus far reported, first individual to be diagnosed with tumor testing and two individuals with variants at the Arg882 domain, bringing the total number of reported cases to 82. Patients reported herein have additional clinical features not previously reported in TBRS. One patient had congenital diaphragmatic hernia. One patient carrying the recurrent p.Arg882HisDNMT3Avariant, who was previously reported as having a phenotype due to a truncating variant in theCLTCgene, developed a ganglioneuroblastoma at 18 months and T‐cell lymphoblastic lymphoma at 6 years of age. Four patients manifested symptoms suggestive of autonomic dysfunction, including central sleep apnea, postural orthostatic hypotension, and episodic vasomotor instability in the extremities. We discuss the molecular and clinical findings in our patients with TBRS in context of existing literature.
Further delineation of the phenotypic spectrum of nevus comedonicus syndrome to include congenital pulmonary airway malformation of the lung and aneurysm
Authors: Sheppard Sarah E. , Smith Anna , Grand Katheryn , Pogoriler Jennifer , Rubin Adam I. , Schindewolf Erica , Fitzgerald Mark P. , Moldenhauer Julie , Laje Pablo , Peranteau William , Bhoj Elizabeth , McMahon Patrick , Castelo‐Soccio Leslie 
Published: January 2020

AbstractNevus comedonicus syndrome (NCS) is a rare epidermal nevus syndrome characterized by ocular, skeletal, and central nervous system anomalies. We present a 23‐month‐old boy with a history of a congenital pulmonary airway malformation (CPAM) of the lung and a congenital cataract who developed progressive linear and curvilinear plaques of dilated follicular openings with keratin plugs (comedones) on parts of his scalp, face, and body consistent with nevus comedonicus. MRI of the brain demonstrated an aneurysm of the right internal carotid artery. Genetic testing identified NEK9 c.1755_1757del (p.Thr586del) at mean allele frequency of 28% in the nevus comedonicus. This same mutation was present in the CPAM tissue. This is the first case of a CPAM in a patient with an epidermal nevus syndrome. This case expands the phenotype of nevus comedonicus syndrome to include CPAM and vascular anomalies.
Studies on the curing behavior, thermal, and mechanical properties of epoxy resin‐co‐amine‐functionalized lead phthalocyanine
Authors: Zu Li‐Wu , Li Ji‐dong , Gao Bao‐Chang , Pan Zhong‐Cheng , Wang Jun , Liu Wen‐Bin , Zegaoui Abdeldjalil , Dayo Abdul Qadeer 
Published: January 2020

AbstractA high performance copolymer was prepared by using epoxy (EP) resin as matrix and 3,10,17,24‐tetra‐aminoethoxy lead phthalocyanine (APbPc) as additive with dicyandiamide as curing agent. Fourier‐transform infrared spectroscopy, dynamic mechanical analysis (DMA), differential scanning calorimetric analysis (DSC), and thermogravimetric analysis (TGA) were used to study the curing behavior, curing kinetics, dynamic mechanical properties, impact and tensile strength, and thermal stability of EP/APbPc blends. The experimental results show that APbPc, as a synergistic curing agent, can effectively reduce the curing temperature of epoxy resin. The curing kinetics of the copolymer was investigated by non‐isothermal DSC to determine kinetic data and measurement of the activation energy. DMA, impact, and tensile strength tests proved that phthalocyanine can significantly improve the toughness and stiffness of epoxy resin. Highest values were seen on the 20 wt% loading of APbPc in the copolymers, energy storage modulus, and impact strength increased respectively 388.46 MPa and 3.6 kJ/m2, Tg decreased 19.46°C. TGA curves indicated that the cured copolymers also exhibit excellent thermal properties.
Synthesis, characterization, and swelling behavior of poly(N‐hydroxymethylacrylamide) grafted poly(vinyl alcohol)
Authors: Kurşun Fatma , Işıklan Nuran 
Published: January 2020

AbstractIn this study, the graft copolymerization of N‐hydroxymethylacrylamide (NHMAAm) with poly(vinyl alcohol) (PVA) was carried out by using potassium persulfate/N,N,N,N‐tetramethylethylenediamine (K2S2O8) to improve physicochemical properties and functionality of PVA. The structures of PVA‐g‐poly‐NHMAAm (PNHMAAm) copolymers were characterized by Fourier transform infrared, elemental analysis, nuclear magnetic resonance (1H‐NMR), 13C‐NMR, and size exclusion chromatography. Their thermal behaviors were investigated by differential scanning calorimetry and thermogravimetric analysis (TGA). The TGA results indicated that the graft copolymers show better thermal stability then PVA. The effects of reaction time, temperature, NHMAAm, and K2S2O8 concentrations on grafting parameters were examined. The maximum grafting yield (34.01%) was provided when reaction was carried out under optimum conditions (time = 2 hr, T = 40°C, [NHMAAm] = 0.25 M, [K2S2O8] = 4.56 × 10−3 M). Moreover, PVA‐g‐PNHMAAm membranes were prepared and their swelling behaviors were studied. The results demonstrated that swelling degree of graft membranes increased almost 3.5‐fold compared to PVA membrane.
Designing business models in circular economy: A systematic literature review and research agenda
Authors: Centobelli Piera , Cerchione Roberto , Chiaroni Davide , Del Vecchio Pasquale , Urbinati Andrea 
Published: January 2020

AbstractThe concept of circular economy is increasingly receiving attention in different domains, including strategic management, operations management, and technology management. It requires companies to design their business model (i.e., the value network, the relationships with the supply chain partners, and the value propositions towards customers) around a new concept of sustainable development that reduces consumption of natural resources and preserves the environment. However, extant research falls short in terms of explaining how companies design their business model according to the circular economy principles. Starting from this premise, the present paper provides a systematic review of the literature on the design of business models in the context of circular economy, aiming to offer an overview of the state of research and outline a promising research agenda.
Causes of death among cancer patients in the era of cancer survivorship in Korea: Attention to the suicide and cardiovascular mortality
Authors: Oh Chang‐Mo , Lee Dahhay , Kong Hyun‐Joo , Lee Seokmin , Won Young‐Joo , Jung Kyu‐Won , Cho Hyunsoon 
Published: January 2020

AbstractBackgroundImproved cancer survival is expected to increase noncancer deaths; however, detailed causes of death have rarely been discussed. Changing landscapes in mortality patterns and noncancer mortality risks in patients with cancer require evaluation.MethodsWe identified cancer and noncancer‐related causes of death using data from the 2000‐2016 national cancer registry in Korea (n = 2 707 520), and we characterized the leading causes of death and proportionate mortalities over time. Risks of noncancer deaths relative to the general population were estimated using standardized mortality ratios (SMRs).ResultsOf 1 105 607 identified deaths, 87% were due to the primary cancer. Proportionate mortalities of primary cancer among overall deaths remained high in patients with liver (86%) and lung (70%) cancers and in female patients with breast cancer (77%), even 5 to 10 years following diagnosis, whereas proportionate mortalities reduced to ≤50% in patients with stomach (men, 39%; women, 48%), prostate (47%), and female thyroid (27%) cancers. Despite the predominance of index cancer deaths, the proportion of noncancer deaths among all deaths increased over time. There was a 20‐fold increase in cardiovascular disease deaths among patients with cancer from 2000 to 2016, and the risk of suicide among patients with cancer was higher than that among the general population (SMR: 1.68 [95% confidence interval (CI): 1.63‐1.74] in men, SMR: 1.42 [95% CI: 1.33‐1.55] in women).ConclusionsDeaths from primary cancer remain a major concern; however, follow‐up is required for both cancer and noncancer‐related health issues in cancer survivors, especially concerning suicide and cardiovascular deaths.
Association between socioeconomic factors at diagnosis and survival in breast cancer: A population‐based study
Authors: Ji Peng , Gong Yue , Jiang Chang‐Chuan , Hu Xin , Di Gen‐Hong , Shao Zhi‐Ming 
Published: January 2020

AbstractBackgroundThe associations between socioeconomic statuses and survival outcomes of breast cancer remain unclear. No model has included both histological and socioeconomic factors to predict the survival of breast cancer. This study was designed to develop nomograms to predict breast cancer–specific survival (BCSS) and overall survival (OS) with consideration of socioeconomic factors for breast cancer patients.Materials and methodsWe included a total of 207 749 female patients, diagnosed with malignant breast cancer between 2007 and 2012 from the Surveillance, Epidemiology, and End Results database. BCSS and OS were evaluated with Gray's test and log‐rank tests, respectively. Marital statuses, insurance statuses, residence, median household income, poverty rate, unemployment rate, and education level were included as socioeconomic factors in univariate and multivariate Cox regression analyses. Clinicopathological factors and socioeconomic factors were integrated to construct nomograms. Calibration plots and concordance indexes (C‐indexes) were used to evaluate the accuracy and discrimination of the models.ResultsFour and three socioeconomic factors were involved in constructing the nomograms for 3‐, 5‐, and 7‐year BCSS and OS, respectively. The C‐indexes of the final nomograms were higher than those of the TNM staging system for predicting BCSS (0.835 vs 0.782; P < .001) and OS (0.773 vs 0.676; P < .001). The performance of the nomograms for predicting OS was significantly lower when excluding socioeconomic factors (P < .001).ConclusionThese findings may highlight the importance of developing health‐related policies and the necessity of targeted social support‐based interventions for high‐risk patients.
Prognostic factors of adjuvant chemotherapy discontinuation among stage III colon cancer patients: A survey of medical oncologists and a systematic review and meta‐analysis
Authors: Boyne Devon J. , O'Sullivan Dylan E. , Heer Emily V. , Hilsden Robert J. , Sajobi Tolulope T. , Cheung Winson Y. , Brenner Darren R. , Friedenreich Christine M. 
Published: January 2020

AbstractBackgroundFactors that are prognostic of early discontinuation of adjuvant chemotherapy among stage III colon cancer patients have yet to be described. To address this gap, a survey of medical oncologists and a systematic review and meta‐analysis were conducted.MethodsA survey was distributed in March 2019 to medical oncologists who treat colon cancer within Alberta, Canada. Clinicians were asked to rank the prognostic importance of a set of variables using a Likert scale and agreement was quantified using a weighted Cohen's kappa. In addition, we systematically searched four databases up to July 2019. Meta‐analyses were conducted using a random‐effects model.ResultsOf the 25 clinicians who were sent the survey, 14 responded. Overall, there was no agreement regarding which variables were prognostic of early discontinuation (weighted Cohen's kappa = 0.12; 95% CI = 0.05‐0.18). From an initial 3927 articles, 18 investigations were identified for inclusion in our review. Based upon evidence from both the survey and the systematic review, the following four variables were identified as being prognostic of early discontinuation: (a) comorbidity (OR2+ vs 0 = 1.53; 95% CI = 1.30‐1.79); (b) performance status (ORECOG 2+ vs 0‐1 = 1.33; 95%CI = 1.07‐1.65); (c) T stage (ORT4 vs T1‐2 = 1.57; 95% CI = 0.99‐2.50); and (d) chemotherapy regimen (estimates not pooled due to heterogeneity). In addition to these factors, there was some suggestion that age, marital status/social support, muscle mass, N stage, and tumor grade had prognostic value.ConclusionsCurrent evidence is heterogeneous and limited. Additional research is needed to confirm our findings and to explore additional prognostic factors.
A Structure‐Activity Relationship between the Veratrum Alkaloids on the Antihypertension and DNA Damage Activity in Mice
Authors: Cong Yue , Wu Yantong , Shen Shan , Liu Xiping , Guo Jinggong 
Published: January 2020

AbstractVeratrum plant contains a family of compounds called steroidal alkaloids which have been previously reported to cause DNA damage and blood pressure decrease in vivo. In this study, the antihypertensive effects and DNA damage in brain cells of 12 steroidal alkaloids separated from Veratrum plant were all evaluated to develop a relationship among chemical structure, antihypertensive activity and neurotoxicity by utilization of chemical principal component analysis (PCA) and hierarchical cluster analysis (HCA). Twelve steroidal alkaloids markedly reduced high blood pressure of hypertensive mice and also similarly induced varying degrees of DNA single‐strand breaks in mouse cerebellum and cerebral cortex after oral administration. On the basis of the PCA and HCA results, it was suggested that the 3‐carboxylic esters and benzene group play a core role in the DNA damage of brain cells, while more hydroxy groups in the A‐ring and B‐ring structure of jervine‐type alkaloid led to stronger antihypertensive activity. The primary structure, activity and neurotoxicity relationship were discussed briefly.
Environmentally Friendly Eutectogels Comprising l‐amino Acids and Deep Eutectic Solvents: Efficient Materials for Wastewater Treatment
Authors: Marullo Salvatore , Meli Alessandro , Dintcheva Nadka. Tz. , Infurna Giulia , Rizzo Carla , D'Anna Francesca 
Published: January 2020

AbstractCurrent concerns for sustainability and the environment make low‐impact materials desirable for environmental remediation and, in particular wastewater treatment. We obtained supramolecular gels of l‐amino acids in the deep eutectic solvent formed by choline chloride and phenylacetic acid. After gel characterization, and investigating gel–sol transition temperatures, gelation kinetics, rheological properties, and morphology, the gels were applied as sorbents to remove cationic dyes from aqueous solutions. The effects of the pH, dye nature, volume, and concentration of wastewater were analyzed, and the best result was obtained with a l‐phenylalanine‐based eutectogel. It can be reused for at least 9 times without losing efficiency, also with dye mixtures. Interestingly, this gel can be loaded onto columns to decolorize flowing solutions, achieving 85 % of removal efficiency in only 10 minutes and allowing its reuse for at least 4 cycles. In terms of adsorption capacity, this eutectogel is competitive with efficient gel‐based dye sorbent systems, with a value 1930 mg/g reached at a high concentration of rhodamine B 479 mg/L.
Effects of corporate environmental responsibility strength and concern on innovation performance: The moderating role of firm visibility
Authors: Wu Weiwei , Liang Zhou , Zhang Qi 
Published: January 2020

AbstractBased on stakeholder theory, this research aims to examine the effects of the two dimensions of corporate environmental responsibility (CER), which are CER strength and CER concern, on firm innovation performance, and the moderating effect of firm visibility on these relationships. Using data on Chinese firms listed on Shenzhen stock exchange from 2006 to 2015, this research finds that CER strength positively affects firm innovation performance while CER concern negatively affects innovation performance. These relationships are stronger for firms with greater visibility. This research provides insights for understanding the relationship between CER and innovation performance and has important managerial implications for firms to manage their environmental behaviors and improve innovation performance to achieve sustainable development.
Solvent Effects on Degradative Condensation Side Reactions of Fructose in Its Initial Conversion to 5‐Hydroxymethylfurfural
Authors: Fu Xing , Hu Yexin , Zhang Yanru , Zhang Yucheng , Tang Dianyong , Zhu Liangfang , Hu Changwei 
Published: January 2020

AbstractInvited for this month′s cover is the group of Liangfang Zhu and Changwei Hu at Sichuan University. The image shows a general understanding on the solvent‐controlled formation of oligomers (the possible precursors of humins) accompanying with formation of small‐molecular carboxylic acids as by‐products in the initial reaction stage of fructose dehydration. The Full Paper itself is available at 10.1002/cssc.201902309.