bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systematic review of the prevalence, symptomatology and management options of sexual dysfunction in women with multiple sclerosis
Authors: Polat Dunya Cansu , Tulek Zeliha , Uchiyama Tomoyuki , Haslam Collette , Panicker Jalesh N. 
Published: November 2019

AbstractAimsSexual dysfunction (SD) is highly prevalent in women with multiple sclerosis (MS), however little is known about treatment options. The aim of this paper is to review the prevalence, symptomatology, and management options of sexual dysfunction in women with MS.MethodsThe Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, CINAHL, AMED, PsycINFO, PEDro, Database of International Rehabilitation Research, Occupational Therapy Systematic Evaluation of Evidence, ClinicalTrials.gov, and Current Controlled Trials databases were searched. No limitations were placed on the date. A critical appraisal of the literature on SD in women with MS was performed according to the PRISMA statement. Two reviewers screened and extracted data. Study quality was evaluated using a standardized tool.ResultsA search of 12 databases identified 61 relevant studies (33 observational, 14 case‐control, 4 follow up, 10 interventional). Significant variability in the prevalence of SD and questionnaires used to evaluate SD were observed. The most commonly reported sexual difficulties were problems with desire, arousal, and orgasm. Different demographics and MS‐related characteristics were found to contribute to SD. Few studies have evaluated interventions for treating SD, and bias was high because of the weak quality of trial designs.ConclusionsSD in women with MS is multidimensional, comparable in prevalence with other neurological disorders and increases with advancing disease. Studies evaluating practical strategies and pharmacological interventions are few, and properly designed trials using MS‐specific validated outcome measures of SD are required to inform evidence‐based treatment options for this high impact MS‐related dysfunction.
Valuing happiness predicts higher well‐being: The moderating role of acceptance
Authors: Zhao Yitong , Wang Qing , Wang Jingyi 
Published: November 2019

AbstractRecent research has found that individual tendencies to pursue positive hedonic states, defined as Valuing Happiness (VH), might bring about negative well‐being outcomes. However, there lacked consistent evidence to support VH's paradoxical effects beyond European American contexts. The current study aimed to investigate how VH influences individual well‐being within a highly interdependent culture, and additionally, the moderating role of acceptance in their relationship. We surveyed 266 participants online to assess their levels of VH, acceptance (a facet of dispositional mindfulness), well‐being (indicated by life satisfaction, hedonic balance, and psychological well‐being), and depression symptoms. Results showed that VH positively predicted life satisfaction and positive affect in a Chinese sample, even controlling for age. Moreover, the interaction between VH and acceptance was significant for psychological well‐being. VH had a stronger effect on well‐being for people who were low in acceptance than for those who were high in acceptance. These findings suggest that being motivated by happiness values might enhance well‐being in an interdependent context, particularly for those who were less likely to accept their internal experiences. Implications were discussed in light of the motivational processes involved in individual happiness pursuits.
Insights into plasma‐assisted polymerization at atmospheric pressure by spectroscopic diagnostics
Authors: Barletta Federica , Leys Christophe , Colombo Vittorio , Gherardi Matteo , Britun Nikolay , Snyders Rony , Nikiforov Anton 
Published: November 2019

AbstractIn the present work, a polydiagnostic study of an atmospheric pressure plasma jet specifically designed for the deposition of coatings by using an Ar/tetraethyl orthosilicate (TEOS) mixture is undertaken. Both passive and active diagnostic methods are utilized to shed light on the complexity of gas‐phase mechanisms of precursor fragmentation. A detailed characterization is performed by (fast imaging) optical emission spectroscopy (OES) to clarify the spatial–temporal behavior of excited species. The influence of the TEOS admixture on gas temperature is studied by OES and Rayleigh scattering techniques. The evolution of streamers and their influence on radical formation in the treatment zone is also discussed.
Diaphragmatic electromyography in preterm infants: The influence of electrode positioning
Authors: van Leuteren Ruud W. , Bekhuis Robin E. , de Waal Cornelia G. , de Jongh Frans H. , van Kaam Anton H. , Hutten Gerard J. 
Published: November 2019

AbstractObjectiveTo determine the effect of changing electrode positions on vital signs and respiratory effort parameters measured with transcutaneous electromyography of the diaphragm (dEMG) in preterm infants.MethodsIn this observational study, simultaneous dEMG measurements were performed at the standard position and at one alternative electrode position (randomly assigned to lateral, superior, medial, inferior to the standard placement, or dorsal). The activity of the diaphragm was measured for 1 hour at both positions. Main outcome measures were the agreement in heart rate (HR), respiratory rate (RR), and percentage difference in dEMG parameters of respiratory effort (peak and tonic activity, amplitude, area under the curve, and frequency content) between the standard and alternative electrode positions.ResultsThirty clinically stable preterm infants (gestational age 30.1 ± 3.0 weeks) with either no or noninvasive respiratory support were included. Agreement in HR was excellent at all positions (ICC > 0.95) while RR agreement showed more diversity (ICC range 0.40‐0.86). Mixed modeling of dEMG parameters revealed that medial and inferior placement measured the weakest signals (median 75.5% and 64.5% lower dEMG amplitude). Lateral electrode placement showed the highest similarity to standard positioning (median 23.5% lower amplitude).ConclusionMeasuring HR showed high similarity at all positions. However, registration of RR and respiratory effort is clearly influenced by the electrode position. Electrodes in the same transversal plane as the diaphragm, and at sufficient distance from each other, provide the best agreement with the standard positioning.
The effects of high‐frequency chest compression on end‐tidal CO2
Authors: Weiner Gabriel A. , Forno Erick , Weiner Daniel J. 
Published: November 2019

AbstractIntroductionHigh‐frequency chest compression (HFCC) is used for airway clearance, but may have other effects. We sought to determine if HFCC provides augmented ventilation.MethodsDuring treatment, capnometry was measured with the HFCC vest set to 6‐20 Hz. End‐tidal CO2 (etCO2) was compared using generalized estimating equations.ResultsTwenty‐four measurements were obtained from 15 subjects with mean age 15.2 ± 2.5 years and forced expiratory volume in one second (FEV1) % predicted 70 ± 23. EtCO2 decreased with HFCC at 6 Hz when compared with baseline (P < .001), with small changes with increasing oscillation frequency. Change in etCO2 was not predicted by FEV1, body mass index, age, or sex.ConclusionsWhile HFCC has been shown to be a suitable method of airway clearance, investigators have failed to demonstrate differences between techniques. Assessment of these methodologies will become important as new airway clearance devices are proposed. Other outcome measures (besides FEV1) may be needed to assess effects of airway clearance, and we propose that physiologic measures might be one such measure which deserves further exploration.
Evaluation of pharmacokinetics and safety of cetuximab with cisplatin/carboplatin in patients with advanced solid tumor: Result from phase II studies
Authors: Perez Raymond P. , Chen Eric , Thaddeus Beck J. , Shirai Keisuke , Neil Hayes David , Shen Tong , Baldwin John R. , Bryant Katherine B. , He Shuang , Chin Steve 
Published: November 2019

AbstractThe pharmacokinetics and potential drug–drug interactions between cetuximab and cisplatin or carboplatin from two studies (JXBA and JXBB) were evaluated. These studies were multicenter, open‐label phase II trials designed to evaluate the drug–drug interactions between cetuximab (400 mg m−2 initial dose) and cisplatin (JXBA; 100 mg m−2) or carboplatin (JXBB; area under the curve [AUC] = 5 mg × min mL−1) with or without 5‐fluorouracil (5FU) in patients with advanced solid tumors. Concentrations of cetuximab, cisplatin and carboplatin were determined using analytical methods. The safety and tolerability of cetuximab in combination with cisplatin or carboplatin was also determined in all treated patients. The JXBA study showed that cetuximab serum concentrations were similar when cetuximab was administered alone or in combination with cisplatin. The Cmax, tmax and overall AUC for the cetuximab group (194 µg mL−1, 2.0 hour, 14 900 µg × h mL−1) and the cetuximab and cisplatin combination group (192 µg mL−1, 1.99 hour, 16 300 µg × h mL−1) were similar. The JXBB study showed that mean cetuximab serum concentrations were similar when cetuximab was administered alone or in combination with carboplatin. The Cmax, tmax and overall AUC for the cetuximab group (199 µg mL−1, 1.15 hour, 17 200 µg × h mL−1) and the cetuximab and carboplatin combination group (199 µg mL−1, 3.17 h, 16 800 µg × h mL−1) were similar. Both studies showed that the safety profile was consistent with known side effects of cetuximab, platinum–based therapies and 5‐FU. There was no clinically relevant change in cetuximab pharmacokinetics when it was administered in combination with cisplatin or carboplatin.
Emitting/Sensitizing Ions Spatially Separated Lanthanide Nanocrystals for Visualizing Tumors Simultaneously through Up‐ and Down‐Conversion Near‐Infrared II Luminescence In Vivo
Authors: Li Yingying , Zhang Peisen , Ning Haoran , Zeng Jianfeng , Hou Yi , Jing Lihong , Liu Chunyan , Gao Mingyuan 
Published: November 2019

AbstractNear‐infrared lights have received increasing attention regarding imaging applications owing to their large tissue penetration depth, high spatial resolution, and outstanding signal‐to‐noise ratio, particularly those falling in the second near‐infrared window (NIR II) of biological tissues. Rare earth nanoparticles containing Er3+ ions are promising candidates to show up‐conversion luminescence in the first near‐infrared window (NIR I) and down‐conversion luminescence in NIR II as well. However, synthesizing particles with small size and high NIR II luminescence quantum yield (QY) remains challenging. Er3+ ions are herein innovatively combined with Yb3+ ions in a NaErF4@NaYbF4 core/shell manner instead of being codoped into NaLnF4 matrices, to maximize the concentration of Er3+ in the emitting core. After further surface coating, NaErF4@NaYbF4@NaYF4 core/shell/shell particles are obtained. Spectroscopy studies are carried out to show the synergistic impacts of the intermediate NaYbF4 layer and the outer NaYF4 shell. Finally, NaErF4@NaYbF4@NaYF4 nanoparticles of 30 nm with NIR II luminescence QY up to 18.7% at room temperature are obtained. After covalently attaching folic acid on the particle surface, tumor‐specific nanoprobes are obtained for simultaneously visualizing both subcutaneous and intraperitoneal tumor xenografts in vivo. The ultrahigh QY of down‐conversion emission also allows for visualization of the biodistribution of folate receptors.
Placental gas exchange during amniotic carbon dioxide insufflation in sheep
Authors: Amberg B. J. , DeKoninck P. L. J. , Kashyap A. J. , Skinner S. M. , Rodgers K. A. , McGillick E. V. , Deprest J. A. , Hooper S. B. , Crossley K. J. , Hodges R. J. 
Published: November 2019

ABSTRACTObjectiveInsufflation of the amniotic cavity with carbon dioxide (CO2) is used clinically to improve visibility during complex fetoscopic surgery. Insufflation with heated, humidified CO2 has recently been shown to reduce fetal hypercapnia and acidosis in sheep, compared with use of cold and dry CO2, but the underlying mechanisms are unclear. The aim of this study was to investigate whether differences in placental CO2 and oxygen (O2) exchange during insufflation with heated and humidified vs cold and dry CO2 could explain these findings.MethodsThirteen fetal lambs at 105 days of gestation (term, 146 days) were exteriorized partially, via a midline laparotomy and hysterotomy, and instrumented with an umbilical artery catheter, an umbilical vein catheter and a common umbilical vein flow probe. Arterial and venous catheters and flow probes were also inserted into the maternal uterine circulation. Six ewes were insufflated with cold, dry CO2 (22°C; 0–5% humidity) and seven with heated, humidified CO2 (40°C; 95–100% humidity) at 15 mmHg for 180 min. Blood‐flow recordings and paired arterial and venous blood gases were sampled from uterine and umbilical vessels. Rates of placental CO2 and O2 exchange were calculated.ResultsAfter 180 min of insufflation, fetal survival was 33% (2/6) using cold, dry CO2 and 71% (5/7) using heated, humidified CO2. By 120 min, fetuses insufflated with heated, humidified CO2 had lower arterial CO2 levels and higher arterial pH compared to those insufflated with cold, dry gas. Insufflation decreased significantly placental gas exchange in both groups, as measured by rates of both (i) fetal CO2 clearance and O2 uptake and (ii) maternal O2 delivery and CO2 uptake from the fetal compartment.ConclusionsLower arterial CO2 and higher pH levels in fetuses insufflated with heated and humidified, compared to cold and dry, CO2 could not be explained by differences in placental gas exchange. Instead, heated and humidified insufflation appeared to reduce fetal CO2 absorption from the uterus, supporting its use in preference to cold, dry CO2. © 2019 International Society of Ultrasound in Obstetrics and Gynecology
Energy decay estimates for a two‐dimensional coupled wave‐plate system with localized frictional damping
Authors: Guo Ya‐Ping , Wang Jun‐Min , Zhao Dong‐Xia 
Published: November 2019

AbstractThis paper is devoted to the energy decay estimates for the two‐dimensional coupled wave‐plate system with local frictional damping in a bounded domain. The frictional damping is only distributed in the part of the plate's or wave's domain, and the other is stabilized by the transmission through the interface of the plate's and wave's domains. Using the frequency domain approach and the multiplier technique, we show respectively that the energy of the system decays polynomially under some geometric condition when the frictional damping only acts on the part of the plate, and the energy of the system is exponentially stable when the frictional damping acts only on the other part of the wave.
Handling Languaging During Empirical Research: Ethnography as Action in and Across Time and Physical-Virtual Sites
Authors: Bagga-Gupta Sangeeta , Messina Dahlberg Giulia , Gynne Annaliina 
Published: November 2019

AbstractThis chapter builds upon data from different multi-sited ethnographic projects that have been conducted and are ongoing in different geopolitical and digital spaces. This chapter is framed within sociocultural, dialogical and decolonial perspectives which highlight that learning is a situated and distributed process where communication is collaboratively achieved. In these traditions, while the rich potentials and dimensions of human communication in concert with intellectual and material tools are recognized, attention in analysis has tended to be dominated over the decades by an “oral language bias”. The findings presented in this chapter raise epistemological and pragmatic challenges related to the very doing of ethnographic fieldwork and illustrate some closely related theoretical and methodological issues, specifically in settings where linguistic heterogeneity is the norm.
The Story Event “The Beauty and the Beast” in Second Life: Literature Studies and the (Non-)Adoption of Virtual Worlds
Authors: Lindberg Ylva 
Published: November 2019

AbstractThe aim of this study is to gain insight into how digital three-dimensional worlds generate new ways of (1) studying literary genres, (2) “prosuming” literary story-events, and (3) supporting the learning of literary competencies. In a virtual world, the frontiers between the factual and the fictional are replaced and blurred in similar ways as in fictional literature, though the sensation of reality is enhanced, since the medium allows for intense interaction, where the technology and the human body are involved. Contents and interactions in the virtual world Second Life are explored through the lenses of literature, in order to observe how literary components play out in the environment. The methodology is inspired by ethnography, and comprises methods of immersed engagement and observations, as well as visual and textual snapshot documentations in-world. The results offer perspectives on affordances and hinders for integrating virtual worlds in learning and literature studies.
“Oh It Was a Woman! Had I Known I Would Have Reacted Otherwise!”: Developing Digital Methods to Switch Identity-Related Properties in Order to Reveal Linguistic Stereotyping
Authors: Lindvall-Östling Mattias , Deutschmann Mats , Steinvall Anders 
Published: November 2019

AbstractThis chapter describes the methodological processes involved in the project Raising Awareness using Virtual Experiencing (RAVE), funded by the Swedish Research council. The aim of the project is to develop experiential pedagogic approaches aimed at raising sociolinguistic language awareness about stereotyping and language. A key feature of the method consists of updated matched-guise techniques, whereby the same recording is digitally manipulated to alter the voice quality of a speaker to sound “male” or “female”, for example. These versions of the recording are then used as input stimuli for a response phase aimed at illustrating how we as listeners react differently to a person, and what is being said, depending on the perceived identity of the speaker. This chapter then illustrates how results are used as a starting point for discussions with respondents (student groups) on issues related to stereotyping and language, with the aim to raise awareness and self-reflection.
Fantasy of Conviviality: Banalities of Multicultural Settings and What We Do (Not) Notice When We Look at Them
Authors: Nowicka Magdalena 
Published: November 2019

AbstractThis contribution looks back at the last years of the conviviality debate which attempts to grasp the chimerical nature of mundane human encounters. It uses the term ‘fantasy’ to point to how conviviality emerges in the literature as an imaginary of the relationship between me/us and them/others. It argues that this imaginary is embedded in the Western modern normative order that perceives of an individual as a collaborating social being. It argues that shifting of the debate’s attention away from collaboration of individuals towards sociality would be productive and allow us to address issues otherwise omitted, such as relations of family, friendship, care, intimacy, private sphere, power and identity and gender relations. In turn, Thinking of conviviality beyond the Western modern imaginary could thus help us it developing the full potential of the term conviviality.
Cosmopolitanism as Utopia
Authors: Lettevall Rebecka 
Published: November 2019

AbstractBecause of its rhetorical nature, the notion of cosmopolitanism is sometimes understood as having a fixed definition. As this is not the case, parts of this overstrained concept have been replaced by the concept of conviviality. In some discussions, Immanuel Kant’s understanding of hospitality as a cosmopolitan right has been criticised and, in some cases, this has resulted in a rejection of the idea of cosmopolitanism. This has not least been the case in recent debates about refugee arrivals in Europe. This chapter, however, argues that it is worth paying attention to the historicity of conceptual frameworks, and that cosmopolitanism should not be abandoned, but instead be read as a utopian idea—as a reflexive method for imagining better or alternative futures in time and space.
A Convivial Journey: From Diversity in Istanbul to Solidarity with Refugees in Denmark
Authors: Duru Deniz Neriman 
Published: November 2019

AbstractThis chapter presents my analytical journey from conviviality, a concept used for analysing diversity in Istanbul to overcome the pitfalls of multiculturalism and coexistence theories, to the development of the concept of convivial solidarity for the analysis of transnational civil society organisations that support refugees and migrants in Denmark. Convivial solidarity is my construct and I use it tentatively to argue that it takes its grounds from the daily life and social interactions between people without putting boundaries in between groups, by stressing what unites people, what they share as humans, and their fight for convivial living. Nonetheless, it is not limited to social interactions but has also political and legal grounding.
Bringing Conviviality into Methods in Media and Migration Studies
Authors: Cory Erin 
Published: November 2019

Abstract‘Conviviality’ conveys a deep concern with how we understand modes of human connection and possesses a renewed charge in the context of current migration. Within the extant literature, however, there exists little thinking on the methodological possibilities of conviviality: What can conviviality do, or rather, what can researchers do with it in efforts to understand the connections between media, mediation, and migration? How can researchers across disciplines do conviviality as part of an interventionist research praxis? In this chapter, I draw on a research project in which conviviality becomes a prism to understand media practices related to migration and refugees, and I discuss how the concept is best appropriated as a methodological tool in research designs informing current and future activist-based studies.
Soziale Netzwerke und die Gesundheit von Alleinerziehenden
Authors: Keim-Klärner Sylvia 
Published: November 2019

ZusammenfassungAlleinerziehende verfügen im Durchschnitt über eine schlechtere psychische und physische Gesundheit als verheiratete Eltern. Dieses Kapitel geht daher der Frage nach, welche Relevanz soziale Netzwerke und ihre Charakteristika in diesem Zusammenhang haben. Spezifisch netzwerkanalytische Studien zur Gesundheit Alleinerziehender sind selten, der (positive) Effekt von sozialer Unterstützung hingegen ist recht gut belegt. Der Vorteil einer netzwerkanalytische Perspektive liegt darin, dass sie über das Konzept sozialer Unterstützung hinaus geht und auch andere Wirkmechanismen einbezieht. Zudem öffnet sie den Blick auch für konflikthafte Beziehungen oder ambivalente Beziehungsinhalte. Damit kann eine soziale Netzwerkanalyse der Komplexität sozialer Beziehungsgeflechte in besonderem Maße gerecht werden. Des Weiteren können sich Netzwerkstudien auch damit auseinandersetzen, auf welche Weise soziale Beziehungsgeflechte die Gesundheitswirksamkeit sozialer Ungleichheiten verstärken oder abmildern. Noch wissen wir wenig darüber, unter welchen Umständen und inwieweit welche Arten von sozialen Netzwerken in der Lage sind, soziale Ungleichheiten zu kompensieren, sodass diese nicht gesundheitsrelevant werden.