bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraspecific variation in a lizard from the Central Mexican Plateau: intersexual differences in size and shape explored
Authors: Lozano Abraham , Ramírez-Bautista Aurelio , Cruz-Elizalde Raciel 
Published: April 2020

AbstractMorphological adaptations of individuals are directly (or indirectly) determined by the environment. Depending on sex, these adaptations may vary in different ways, given that different selective forces may be operating on organisms. Here, we evaluate intraspecific morphological variation (size and shape) in two populations of Sceloporus grammicus that occur in different structural habitats (trees and rocks). No difference in overall body size was found between the two populations. However, strong differences were found in body shape; the tree population was characterized by having shorter hindlimb proportions than the rock population, which agrees with the theory of biomechanical models. Furthermore, our results show that this species is dimorphic in size and shape, both in sex and population effects. A review of the literature suggests that the large overall body size and relatively longer distal segments of males could be an advantage for defending their territory, and the observation that females had relatively longer head length may be related to trophic niche divergence; however, this remains to be tested. Detailed quantification of behaviour, performance and reproductive characteristics must be performed to shed light on the evolution of sexual dimorphism in this widely distributed species in Mexico.
In Their Own Words: Student Perceptions of Restorative Practices
Authors: Skrzypek Candra , Bascug Erin W , Ball Annahita , Kim Wooksoo , Elze Diane 
Published: April 2020

Abstract
Restorative practices (RPs) are promising nonpunitive approaches to discipline in schools, yet researchers often overlook students’ perspectives. The current study used a mixed-methods approach to explore RP Circle experiences of urban, low-income, and predominantly Black middle school students with attention to the diversity of their experiences by grade level, race, and gender. Quantitative results indicated that younger students reported learning about their behavior by participating in RP Circles. In general, boys felt that Circles supported their nonviolent problem-solving skills more than girls did. Black girls were significantly less likely to endorse the effectiveness of RP Circles to help them solve problems without violence and help them learn about their behavior in comparison with girls of other racial or ethnic backgrounds. Qualitative findings highlighted the benefits of RP Circles in promoting communication, expressing thoughts and feelings, pers pective taking, and opportunity for learning. The study highlights the importance of approaching RP from an intersectional lens and integrating youths’ perspectives into programming.
Binary deviations from single object astrometry
Authors: Penoyre Zephyr , Belokurov Vasily , Wyn Evans N , Everall A , Koposov S E 
Published: April 2020

ABSTRACT
Most binaries are undetected. Astrometric reductions of a system using the assumption that the object moves like a single point mass can be biased by unresolved binary stars. The discrepancy between the centre of mass of the system (which moves like a point mass) and the centre of light (which is what we observe) introduces additional motion. We explore the extent to which binary systems affect single object model fit to astrometric data. This tells us how observations are diluted by binaries and which systems cause the largest discrepancies – but it also allows us to make inferences about the binarity of populations based on observed astrometric error. By examining a sample of mock observations, we show that binaries with periods close to 1 yr can mimic parallax and thus bias distance measurements, while long-period binaries can introduce significant apparent proper motion. While these changes can soak up some of the error introduced by the binary, the total deviation from the best-fitting model can be translated into a lower limit on the on-sky separation of the pair. Throughout, we link these predictions to data from the Gaia satellite, while leaving the conclusions generalizable to other surveys.
The impact of quenching on galaxy profiles in the simba simulation
Authors: Appleby Sarah , Davé Romeel , Kraljic Katarina , Anglés-Alcázar Daniel , Narayanan Desika 
Published: April 2020

ABSTRACT
We study specific star formation rate (sSFR) and gas profiles of star-forming (SF) and green valley (GV) galaxies in the simba cosmological hydrodynamic simulation. SF galaxy half-light radii (Rhalf) at z = 0 and their evolution (∝(1 + z)−0.78) agree with observations. Passive galaxy Rhalf agree with observations at high redshift, but by z = 0 are too large, owing to numerical heating. We compare simbaz = 0 sSFR radial profiles for SF and GV galaxies to observations. simba shows strong central depressions in star formation rate (SFR), sSFR, and gas fraction in GV galaxies and massive SF systems, qualitatively as observed, owing to black hole X-ray feedback, which pushes central gas outwards. Turning off X-ray feedback leads to centrally peaked sSFR profiles as in other simulations. In conflict with observations, simba yields GV galaxies with strongly dropping sSFR profiles beyond ≳Rhalf, regardless of active galactic nucleus feedback. The central depression owes to lowering molecular gas content; the drop in the outskirts owes to reduced star formation efficiency. simba’s satellites have higher central sSFR and lower outskirts sSFR than centrals, in qualitative agreement with observations. At z = 2, simba does not show central depressions in massive SF galaxies, suggesting simba’s X-ray feedback should be more active at high-z. High-resolution tests indicate central sSFR suppression is not sensitive to numerical resolution. Reproducing the central sSFR depression in z = 0 GV galaxies represents a unique success of simba. The remaining discrepancies highlight the importance of SFR and gas profiles in constraining quenching mechanisms.
Dynamical friction with radiative feedback – II. High-resolution study of the subsonic regime
Authors: Velasco Romero David A , Masset Frédéric S 
Published: April 2020

ABSTRACT
Recent work has suggested that the net gravitational force acting on a massive and luminous perturber travelling through a gaseous and opaque medium can have same direction as the perturber’s motion (an effect sometimes called negative dynamical friction). Analytic results were obtained using a linear analysis and were later confirmed by means of non-linear numerical simulations which did not resolve the flow within the Bondi sphere of the perturber, hence effectively restricted to weakly perturbed regions of the flow. Here we present high-resolution simulations, using either 3D Cartesian or 2D cylindrical meshes that resolve the flow within the Bondi sphere. We perform a systematic study of the force as a function of the perturber’s mass and luminosity, in the subsonic regime. We find that perturbers with mass M smaller than a few Mc ∼ χcs/G are subjected to a thermal force with a magnitude in good agreement with linear theory (χ being the thermal diffusivity of the medium, cs the adiabatic sound speed, and G the gravitational constant), while for larger masses, the thermal forces are only a fraction of the linear estimate that decays as M−1. Our analysis confirms the possibility of negative friction (hence a propulsion) on sufficiently luminous, low-mass embryos embedded in protoplanetary discs. Finally, we give an approximate expression of the total force at low Mach number, valid both for subcritical (M &lt; Mc) and supercritical (M &gt; Mc) perturbers.
X-ray observations of luminous dusty quasars at z &gt; 2
Authors: Lansbury G B , Banerji M , Fabian A C , Temple M J 
Published: April 2020

ABSTRACT
We present new X-ray observations of luminous heavily dust-reddened quasars (HRQs) selected from infrared (IR) sky surveys. HRQs appear to be a dominant population at high redshifts and the highest luminosities, and may be associated with a transitional ‘blowout’ phase of black hole and galaxy co-evolution models. Despite this, their high-energy properties have been poorly known. We use the overall sample of 10 objects with XMM–Newton coverage to study the high-energy properties of HRQs at $\langle$Lbol$\rangle$ =1047.5 erg s−1 and $\langle$z$\rangle$ =2.5. For seven sources with strong X-ray detections, we perform spectral analyses. These find a median X-ray luminosity of $\left\langle L_{\rm 2\!-\!10\, keV} \right\rangle = 10^{45.1}$ erg s−1, comparable to the most powerful X-ray quasars known. The gas column densities are NH = (1–8) × 1022 cm−2, in agreement with the amount of dust extinction observed. The dust-to-gas ratios are sub-Galactic, but are higher than found in local AGN. The intrinsic X-ray luminosities of HRQs are weak compared to the mid-IR ($L_{\rm 6\, \mu m}$) and bolometric luminosities (Lbol), in agreement with findings for other luminous quasar samples. For instance, the X-ray to bolometric corrections range from κbol ≈ 50 to 3000. The moderate absorption levels and accretion rates close to the Eddington limit ($\langle$λEdd$\rangle$ =1.06) are in agreement with a quasar blowout phase. Indeed, we find that the HRQs lie in the forbidden region of the NH–λEdd plane, and therefore that radiation pressure feedback on the dusty interstellar medium may be driving a phase of blowout that has been ongoing for a few 105 yr. The wider properties, including [O iii] narrow-line region kinematics, broadly agree with this interpretation.
C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation
Authors: Wang Guyi , Wu Chenfang , Zhang Quan , Wu Fang , Yu Bo , Lv Jianlei , Li Yiming , Li Tiao , Zhang Siye , Wu Chao , Wu Guobao , Zhong Yanjun 
Published: April 2020

Abstract

Background
Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients diagnosed as mild early may progress to severe cases. However, it is difficult to distinguish these patients in the early stage. The present study aimed to describe the clinical characteristics of these patients, analyze related factors, and explore predictive markers of the disease aggravation.

Methods
Clinical and laboratory data of nonsevere adult COVID-19 patients in Changsha, China, were collected and analyzed on admission. A logistic regression model was adopted to analyze the association between the disease aggravation and related factors. The receiver operating characteristic curve (ROC) was utilized to analyze the prognostic ability of C-reactive protein (CRP).

Results
About 7.7% (16/209) of nonsevere adult COVID-19 patients progressed to severe cases after admission. Compared with nonsevere patients, the aggravated patients had much higher levels of CRP (median [range], 43.8 [12.3–101.9] mg/L vs 12.1 [0.1–91.4] mg/L; P = .000). A regression analysis showed that CRP was significantly associated with aggravation of nonsevere COVID-19 patients, with an area under the curve of 0.844 (95% confidence interval, 0.761–0.926) and an optimal threshold value of 26.9 mg/L.

Conclusions
CRP could be a valuable marker to anticipate the possibility of aggravation of nonsevere adult COVID-19 patients, with an optimal threshold value of 26.9 mg/L.
Medical Students Are Not Essential Workers: Examining Institutional Responsibility During the COVID-19 Pandemic
Authors: Menon Anitha , Klein Edwin J. , Kollars Kate , Kleinhenz Alissa L.W. 
Published: April 2020

In light of the evolving COVID-19 pandemic, the Association of American Medical Colleges (AAMC) and Liaison Committee on Medical Education (LCME) released a joint statement in March 2020 recommending an immediate suspension of medical student participation in direct patient contact. As graduating medical students who will soon begin residency, the authors fully support this recommendation. Though paid health care workers, like residents, nurses, and environmental services staff, are essential to the management of COVID-19 patients, medical students are not. Students’ continued involvement in direct patient care will contribute to SARS-CoV-2 exposures and transmissions and will waste already limited personal protective equipment. By decreasing nonessential personnel in health care settings, including medical students, medical schools will contribute to national and global efforts to “flatten the curve.”
The authors also assert that medical schools are responsible for ensuring medical student safety. Without the protections provided to paid health care workers, students are uniquely disadvantaged within the medical hierarchy; these inequalities must be addressed before medical students are safely reintegrated into clinical roles. Although graduating medical students and institutional leadership may worry that suspending clinical rotations might prevent students from completing graduation requirements, the authors argue the ethical obligation to “flatten the curve” supersedes usual teaching responsibilities. Therefore, the authors request further guidance from the LCME and AAMC regarding curricular exemptions/alternatives and adjusted graduation timelines. The pool of graduating medical students affected by this pause in direct patient contact represents a powerful reserve, which may soon need to be used as the COVID-19 pandemic continues to challenge the U.S. health care infrastructure.
SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FEATURES OF VITREORETINAL LYMPHOMA IN 55 EYES
Authors: Yang Xiaolu , Dalvin Lauren A. , Mazloumi Mehdi , Ferenczy Sandor , Lim Li-Anne S. , Ancona-Lezama David , Shields Jerry A. , Mashayekhi Arman , Shields Carol L. 
Published: April 2020

Purpose:
To evaluate spectral domain optical coherence tomography (SD-OCT) features of vitreoretinal lymphoma (VRL).

Methods:
Review of records and SD-OCT images of vitreoretinal lymphoma evaluated at Ocular Oncology Service, Wills Eye Hospital between July 1, 2000, and April 1, 2019.

Results:
There were 55 eyes of 32 patients included. At presentation, SD-OCT features included vitreous opacities (n = 36, 65%), preretinal deposits (n = 7, 13%), intraretinal deposits (n = 8, 15%), subretinal deposits (n = 20, 36%), retinal pigment epithelium abnormalities (n = 35, 64%), and subretinal pigment epithelium deposits (n = 35, 64%). Of 36 eyes with observed tumor progression, comparison (initial visit vs. time of progression) revealed more intraretinal deposits (17% vs. 50%, P = 0.005) at progression. Of 15 eyes with tumor recurrence, comparison (initial visit vs. time of recurrence) revealed more intraretinal deposits (7% vs. 47%, P = 0.04) at recurrence. At last visit, 39 eyes demonstrated tumor regression. By comparison (initial presentation vs. regression), there were less frequent vitreous opacities (67% vs. 0%, P < 0.001), intraretinal deposits (15% vs. 0%, P = 0.03), subretinal deposits (36% vs. 0%, P < 0.001), and subretinal pigment epithelium deposits (69% vs. 21%, P < 0.001) at regression.

Conclusion:
Using SD-OCT in patients with vitreoretinal lymphoma, local tumor regression correlated with a reduction in vitreous opacities, intraretinal deposits, subretinal deposits, and subretinal pigment epithelium deposits. SD-OCT is useful in judging vitreoretinal lymphoma response to therapy.
Genomic analysis and comparative multiple sequences of SARS-CoV2
Authors: Chang Tai-Jay , Yang De-Ming , Wang Mong-Lien , Liang Kung-How , Tsai Ping-Hsing , Chiou Shih-Hwa , Lin Ta-Hsien , Wang Chin-Tien 
Published: April 2020

Background:
China announced an outbreak of new coronavirus in the city of Wuhan on December 31, 2019; lash to now, the virus transmission has become pandemic worldwide. Severe cases from the Huanan Seafood Wholesale market in Wuhan were confirmed pneumonia with a novel coronavirus (2019-nCoV). Understanding the molecular mechanisms of genome selection and packaging is critical for developing antiviral strategies. Thus, we defined the correlation in 10 severe acute respiratory syndrome coronavirus (SARS-CoV2) sequences from different countries to analyze the genomic patterns of disease origin and evolution aiming for developing new control pandemic processes.

Methods:
We apply genomic analysis to observe SARS-CoV2 sequences from GenBank (http://www.ncbi.nim.nih.gov/genebank/): MN 908947 (China, C1), MN985325 (USA: WA, UW), MN996527 (China, C2), MT007544 (Australia: Victoria, A1), MT027064 (USA: CA, UC), MT039890 (South Korea, K1), MT066175 (Taiwan, T1), MT066176 (Taiwan, T2), LC528232 (Japan, J1), and LC528233 (Japan, J2) for genomic sequence alignment analysis. Multiple Sequence Alignment by Clustalw (https://www.genome.jp/tools-bin/clustalw) web service is applied as our alignment tool.

Results:
We analyzed 10 sequences from the National Center for Biotechnology Information (NCBI) database by genome alignment and found no difference in amino acid sequences within M and N proteins. There are two amino acid variances in the spike (S) protein region. One mutation found from the South Korea sequence is verified. Two possible “L” and “S” SNPs found in ORF1ab and ORF8 regions are detected.

Conclusion:
We performed genomic analysis and comparative multiple sequences of SARS-CoV2. Studies about the biological symptoms of SARS-CoV2 in clinic animals and humans will manipulate an understanding on the origin of pandemic crisis.
The Association Between Fear of Movement, Pain Catastrophizing, Pain Anxiety, and Protective Motor Behavior in Persons With Peripheral Joint Conditions of a Musculoskeletal Origin
Authors: De Baets Liesbet , Matheve Thomas , Timmermans Annick 
Published: April 2020

Objective
The aim of the study was to investigate alterations in motor behavior related to pain-related beliefs in persons with peripheral joint conditions.

Design
This is a systematic review.

Results
Our database search (PubMed, Web of Science, Embase, PsycINFO) identified 7390 articles (until September 2019), and nine articles (344 participants) were selected based on the eligibility criteria for selecting studies, i.e., studies in adults with primary peripheral joint conditions, assessing the influence of fear of movement, catastrophizing or anxiety on motor behavior in terms of kinematics, kinetics, and muscle activity during active movements.
In the acute stage after knee or radius surgery, more catastrophizing and fear were associated with less active joint motion in the operated and adjacent joints. In knee patients in the chronic stage after surgery, increased hip adduction and knee valgus were linked to increased fear of movement during the performance of challenging tasks. Similar results were found in persons with nonsurgical chronic knee pain. During gait, no relation between lower limb kinematics and fear of movement was observed.

Conclusions
Kinematic alterations appear in tandem with pain-related perceptions in acute stages after surgery. Altered kinematics influenced by pain-related beliefs are also seen in persons with chronic nonsurgical and surgical knee pain, when challenging tasks are performed.
The Impact of Social Media on Plastic Surgery Residency Applicants
Authors: Irwin Timothy J. , Riesel Johanna N. , Amador Ricardo O. , Helliwell Lydia A. , Lin Samuel J. , Eberlin Kyle R. 
Published: April 2020

Background
Plastic surgeons have been early adopters of social media, and the efficacy and ethics of this practice have been studied. In addition, plastic and reconstructive surgery (PRS) training programs have begun using social media to connect with the public, including prospective PRS applicants. The ability of social media to attract prospective residency applicants is unknown. This study aims to examine the influence of social media on prospective residency applicants and their perception of a plastic surgery program.

Methods
In the academic years 2018 and 2019, we conducted an anonymous, voluntary survey among applicants applying to both the integrated and independent Harvard PRS residency programs. The survey collected data regarding demographics, social media usage, online information gathering, and PRS programs' social media influence on applicants' perception/rank position of programs.

Results
One hundred nine surveys were completed (23%). Ninety-seven percent of respondents reported searching online for information about residency programs. Twenty percent of respondents noted that a residency program's social media platform “influenced their perception of a program or intended rank position of a program” and 72% of those respondents indicated a positive effect on their perception of a program and its rank list position. At least 15% of respondents were concerned that engaging with a program's social media account would attract attention to their own social media accounts.

Conclusions
Applicants routinely rely on online resources to gather information regarding prospective residency programs. Fear of attracting attention to their own personal social media pages may limit applicants' engagement with PRS programs on social media. However, residency programs can still utilize social media to deliver important messages, especially as social media usage continues to grow.
The role of cryoprecipitate in massively transfused patients: Results from the Trauma Quality Improvement Program database may change your mind
Authors: Ditillo Michael , Hanna Kamil , Castanon Lourdes , Zeeshan Muhammad , Kulvatunyou Narong , Tang Andrew , Sakran Joseph , Gries Lynn , Joseph Bellal 
Published: April 2020

BACKGROUND
Cryoprecipitate was developed for the treatment of inherited and acquired coagulopathies. The role of cryoprecipitate in hemorrhaging trauma patients is still speculative. The aim of our study was to assess the role of cryoprecipitate as an adjunct to transfusion in trauma patients.

METHODS
We performed a 2-year (2015–2016) analysis of the American College of Surgeons-Trauma Quality Improvement Program data set and included all adult trauma patients who received 4 or greater packed red blood cells (pRBCs)/4 hours. Patients were stratified based on receipt of cryoprecipitate within the first 24 hours (cryoprecipitate vs. no-cryoprecipitate). Outcomes were blood products transfused, in-hospital complications, and mortality. Regression analyses were performed.

RESULTS
A total of 19,643 (cryoprecipitate, 4,945; no-cryoprecipitate, 14,698) were included. Mean age was 40 ± 22 years, median Injury Severity Score was 27 [18–40], and Glasgow Coma Scale score was 9 [3–14]. The overall complication rate was 45%, mortality was 47%, and 29% of the patients died in the first 24 hours. Patients in the cryoprecipitate group received a lower volume of plasma (p < 0.01), and pRBCs (p < 0.01). Additionally, patients who received cryoprecipitate had lower rates of 24-hour mortality (p < 0.01) and in-hospital mortality (p < 0.01). However, there was no difference between the two groups regarding complications (p = 0.36) or volume of platelet transfused (p = 0.22). On multivariate logistic regression, the use of cryoprecipitate was associated with decreased (odds ratio [OR], 0.78 [0.63–0.84]; p = 0.02), in-hospital mortality (OR, 0.79 [0.77–0.87]; p = 0.01), but had no association with in-hospital complications (OR, 1.48 [0.71–1.99]; p = 0.31). On linear regression analysis, the use of cryoprecipitate was not associated with 24-hour pRBCs (β = −0.12 [−0.28 to 0.27], p = 0.47), 24-hour plasma (β = −0.06 [−0.21 to 0.43], p = 0.29), and 24-hour platelets (β = −0.24 [−0.09 to 0.33], p = 0.17) transfusion requirements.

CONCLUSION
The adjunctive use of cryoprecipitate in hemorrhaging trauma patients may reduce mortality without affecting in-hospital complications and transfusion requirements. Further studies are needed to better understand its potentially beneficial effects.

LEVEL OF EVIDENCE
Therapeutic, level IV.