bluuebunny/crossref_metadata_2025_split huggingface dataset:
School-Based Interventions Targeting Double Burden of Malnutrition and Educational Outcomes of Adolescents in Low- and Middle-Income Countries: Protocol for a Systematic Review
Authors: Shinde Sachin , Wang Dongqing , Fawzi Wafaie W 
Published: October 2020

Abstract
BackgroundAdolescence is a period of rapid physical growth and transition between childhood to adulthood. However, in many developing countries, nutritional and epidemiological transitions are contributing to surging overnutrition, which, together with prevalent undernutrition, is resulting in the double burden of malnutrition (DBM) among adolescents. Schools as social systems have tremendous but mostly underutilized capacity to facilitate change and address a range of nutritional and associated educational concerns of adolescents and young people. The main objective of this systematic review will be to synthesize the evidence on school-based nutrition interventions that aimed to address the DBM, and the associated educational outcomes among adolescents from low- and middle-income countries (LMICs).MethodsComprehensive literature searches will be conducted in multiple electronic databases, including the Medline (through PubMed), Embase, CENTRAL (through Cochrane Library), CINAHL, and Google Scholar. We will include randomized controlled trials (RCTs), controlled before-after studies, and non-randomized controlled trials examining the effects of nutrition interventions on DBM and educational outcomes among adolescents (10−19−years−old) in LMICs. Two reviewers will independently screen all citations and full-text articles and abstract data. The quality of the included studies will be assessed with the Cochrane Collaboration’s tool for assessing the risk of bias for RCTs and the Risk Of Bias In Non-randomized Studies of Interventions tool for controlled before-after studies and non-randomized controlled trials. DiscussionTo maximize the power of schools as a platform to reinforce the mutually beneficial relationship between adolescent nutrition and education, it is imperative to develop and implement integrated interventions connecting schools, adolescents, parents, communities, and the health care system. The results of this systematic review will provide a comprehensive state of current knowledge on the effectiveness of school-based interventions to enable future research that maximizes the impact and efficiency of integrated approaches to tackle multiple forms of malnutrition among school-going and out-of-school adolescents.Systematic review registrationPROSPERO ID: 211109 (under review)
Challenge of treating cancer amid the COVID-19 pandemic: case of skeletal muscle metastasis from primary carcinoma of the lung mistaken as sarcoma
Authors: Casas Maria Gloria Elisha , Rosario Mamer , Battad Geoffrey , Mercado Adrienne Camille , Hermogenes Trisha Ann , Hernandez Alvin , Dy-Ledesma Janelyn , Alomesen Avelino , Valera Juancho Lorenzo , Dy Arnel Christian 
Published: October 2020

Abstract
Background. The authors report on an extremely rare case of skeletal muscle metastasis from primary lung cancer that involved the radial nerve and humerus, which was “overtreated” with wide tumor resection and frozen autograft reconstruction upon misdiagnosis of sarcoma by intraoperative frozen section, amid pressure of expediting hospital care during the COVID-19 pandemic. Case presentation. A 61-year-old male living outside Metro Manila presented with painful mass in his left distal arm during the enhanced community quarantine, and requested admission upon testing negative for COVID-19. Imaging studies suggested a diagnosis of soft tissue sarcoma involving the radial nerve and humerus, and intending to prevent nosocomial SARS-CoV-2 infection of patient, treatment was expedited by foregoing biopsy and opting for intraoperative frozen section prior to resection. Frozen section findings suggested malignancy intraoperatively, and we proceeded with wide tumor resection and frozen autograft reconstruction of the humerus using plates and screws. However, permanent sections revealed metastatic carcinoma from primary non-small cell lung cancer, with PET scan confirming lung mass in the right apical lobe. Conclusion. The report concludes that establishment of a definite tumor diagnosis by final histopathological analysis is indispensable, even when planning for emergent surgery in the time of COVID-19 pandemic.
Evaluation of SARS-CoV-2 clearance period in patients with COVID-19: a systematic review and meta-analysis
Authors: Okita Yasutaka , Morita Takayoshi , Kumanogoh Atsushi 
Published: October 2020

Abstract
Background: There is insufficient consensus on the viral shedding period in each background of patients with coronavirus disease 2019 (COVID-19).Methods: We conducted a comprehensive systematic review and meta-analysis according to the PRISMA guidelines. PubMed and Web of Science were searched for original studies reporting the viral shedding period in patients with COVID-19. A random effects model was used to calculate the mean number of days from the onset. Subanalysis was performed focusing on age, sex, severity, locality, and treatment.Results Of 55 studies identified, 12 met the selection criteria. The viral shedding period tended to be longer in sputum (19.03 days) than in nasopharynx (14.58 days). The viral shedding period in nasopharynx tended to be longer in severe patients (23.65 days) than in nonsevere patients (12.67 days). It also tended to be longer in patients treated with steroid (21.24 days) than in patients treated without steroid (12.20 days). This period tended to be longer in Asia (16.07 days) than in Europe (12.57 days). Age, sex, and anti-viral drugs did not affect the viral shedding period.Conclusions Severity, steroid usage, and locality may affect the viral shedding period.
Nanopore sequencing and de novo assembly of a misidentified Camelpox vaccine reveals putative epigenetic modifications and alternate protein signal peptides
Authors: Saud Zack , Hitchings Matthew D. , Butt Tariq M. 
Published: October 2020

Abstract
DNA viruses can exploit host cellular epigenetic processes to their advantage; however, the epigenome status of most DNA viruses remains undetermined. Third generation sequencing technologies allow for the identification of modified nucleotides from sequencing experiments without specialized sample preparation, permitting the detection of non-canonical epigenetic modifications that may distinguish viral nucleic acid from that of their host, thus identifying attractive targets for advanced therapeutics and diagnostics. We present a novel nanopore de novo assembly pipeline used to assemble a misidentified Camelpox vaccine. Two confirmed deletions of this vaccine strain in comparison to the closely related Vaccinia virus strain modified vaccinia Ankara make it one of the smallest non-vector derived orthopoxvirus genomes to be reported. Annotation of the assembly revealed a previously unreported signal peptide at the start of protein A38 and several signal peptides that were found to differ from those previously described. Putative epigenetic modifications around various motifs have been identified and the assembly confirmed previous work showing the vaccine genome to most closely resemble that of Vaccinia virus strain Modified Vaccinia Ankara. The pipeline may be used for other DNA viruses, increasing the understanding of DNA virus evolution, virulence, host preference, and epigenomics.
MEDIATISASI LAYANAN PESAN ANTAR MAKANAN DI INDONESIA MELALUI APLIKASI GO-FOOD
Authors: Putra Kadek Aryana Dwi , Hidayatullah Fauzan , Farida Nurul 
Published: October 2020

<p><em>In the era of digital technology the role of the media is very important in changing people's habits and becoming an important part in the lives of social communities. The existence of the media now greatly influences the culture of the community in obtaining information, but the negative side is that the media can control the community and make it subject to the rules made by the media itself. Go-food is present as a medium that makes it easy for people to meet the needs of high urban mobility. The business or trade sector is a sector that has an important role in the process of producing goods and services.</em><em> </em><em>The research method uses a cultural studies approach (cultural studies) in examining the Go-food phenomenon which is reflected in the socio-cultural context of the urban consumer society. Data collection techniques using the study of literature. The results showed that Go-food succeeded in mediating and changing the order of habits of users in meeting food needs through the media. There is a process by which the community begins to depend on the application and the existence of power which results in the community being subject to the rules that are made.</em></p><p> </p>
Coincidence probability of streamflow in water resources area, water receiving area and impacted area: implications for water supply risk and potential impact of water transfer
Authors: Wei Xingchen , Zhang Hongbo , Singh Vijay P. , Dang Chiheng , Shao Shuting , Wu Yanrui 
Published: October 2020

Abstract
Under changing environment, the feasibility and potential impact of an inter-basin water transfer project can be evaluated by employing the coincidence probability of runoff in water sources area (WSA), water receiving area (WRA), and the downstream impacted area (DIA). Using the Han River to Wei River Water Transfer Project (HWWTP) in China as an example, this paper computed the coincidence probability and conditional probability of runoff in WSA, WRA and DIA with the copula-based multivariate joint distribution and quantified their acceptable and unfavorable encounter probabilities for evaluating the water supply risk of the water transfer project and exploring its potential impact on DIA. Results demonstrated that the most adverse encounter probability (dry–dry–dry) was 26.09%, illustrating that this adverse situation could appear about every 4 years. The acceptable and unfavorable probabilities in all encounters were 44.83 and 55.17%, respectively, that is the unfavorable situation would be dominant, implying flood and drought risk management should be paid greater attention in project operation. The conditional coincidence probability (dry WRA & dry DIA if dry WSA) was close to 70%, indicating a requirement for an emergency plan and management to deal with potential drought risk.
Mitigate water shortage by improving hydropower generation strategy of the cascade reservoir system in the Be River Basin, Vietnam
Authors: Thi Thuy Linh Nguyen , Chou Frederick N.-F. 
Published: October 2020

Abstract
To meet increasing water consumption with limited water resources, management approaches that transfer water between purposes must be improved for sustainable development. This entails an urgent requirement for appropriate water resources management within water–energy interaction if severe water shortage occurs occasionally. This study evaluates hydropower generation policies of a cascade reservoir system in the Be River Basin in terms of security of water supply and energy production. The Generalized Water Allocation Simulation Model (GWASIM) was applied to simulate the water use of a complex system of hydropower generation and water supply. Two water allocation scenarios and six alternatives defined by varying monthly generating hours were modeled and compared. The results demonstrate that a compromise between hydropower generation and water supply can be negotiated to reduce the severity of water shortages. Different monthly hours of hydropower generation among alternatives show an effect on improving power production and reliable water supply. This study provides overall insight into the performance of a multi-purpose cascade reservoir system. It will provide a foundation for improving future study of reservoir operations in meeting the increasing demands of water and energy in Vietnam.
Design of up-flow aerated filters for the removal of iron from groundwater
Authors: Thinojah T. , Ketheesan B. , Herath G. B. B. 
Published: October 2020

Abstract
Groundwater contains iron (Fe) that can be difficult to remove by singular physical–chemical methods. The aim of this presented study was to investigate the suitability of up-flow aerated filters as an upgrading step for the removal of total Fe from groundwater. Granular activated carbon (GAC) was applied as a pollutant carrier and compared with Bio-Pac media (BPM) by conducting a column test to treat synthetic groundwater (SGW). Initially two adsorption kinetic studies were done for GAC. The effect of influent Fe concentration, hydraulic retention time (HRT) and air supply to the system were investigated using a column experiment. The sorption result follows pseudo-second-order kinetics with an adsorption amount of 1.36 mg/g. The column experiment results show that around 99% and 70% Fe removal efficiency can be achieved for the best condition of 3 mg/L influent Fe concentration with seven hours HRT for GAC and BPM respectively. The air supply into the column did not show any improvement in Fe removal efficiency. The performance of GAC is found to be much better than that of BPM. All over, the new combined treatment method of aeration followed by filtration was demonstrated to be an effective technique for Fe removal from groundwater and also satisfied the World Health Organization (WHO) drinking water standard for Fe concentration.
Review of characteristics of anammox bacteria and strategies for anammox start-up for sustainable wastewater resource management
Authors: Wu Guangxue , Zhang Tianqi , Gu Mengqi , Chen Zhuo , Yin Qidong 
Published: October 2020

Abstract
Wastewater management has experienced different stages, including pollutant removal, resource recovery, and water nexus. Within these stages, anaerobic ammonia oxidation-based biotechnology can be incorporated for nitrogen removal, which can help achieve sustainable wastewater management, such as reclamation and ecologization of wastewater. Here, the physiology, metabolism, reaction kinetics and microbial interactions of anammox bacteria are discussed, and strategies to start-up the anammox system are presented. Anammox bacteria are slow growers with a high doubling time and a low reaction rate. Although most anammox bacteria grow autotrophically, some types can grow mixotrophically. The reaction stoichiometric coefficients can be affected by loading rates and other biological reactions. Microbial interactions also contribute to enhanced biological nitrogen removal and promote activities of anammox bacteria. The start-up of the anammox process is the key aspect for its practical application, which can be realized through seed selection, system stimulation, and biomass concentration enhancement.
Study on the mechanism of degradation of tetracycline hydrochloride by microwave-activated sodium persulfate
Authors: Gao Yu , Cong Shibo , He Yulun , Zou Donglei , Liu Yuzhi , Yao Bing , Sun Wentian 
Published: October 2020

Abstract
Among the different antibiotics, tetracycline hydrochloride (TCH) is one of the most commonly used. In this study, the activated sodium persulfate (SPS) process induced by microwave (MW) energy was used to treat TCH. The effect of different operational parameters of MW/SPS-treated TCH, such as SPS concentration, TCH concentration, initial pH, and MW power, was investigated. The concentration changes of TCH were determined using a spectrophotometer. The results of radical scavenger experiments indicated that the sulfate radical () was stronger than the hydroxyl radical (·OH). On the basis of high performance liquid chromatography–mass spectrometry (HPLC–MS) analysis, a possible degradation pathway of TCH was proposed. This research indicates that the MW/SPS system is a promising prospect for the treatment of TCH.
Carnauba straw powder treated with bentonite for copper adsorption in aqueous solution: isothermal, kinetic and thermodynamic study
Authors: Pereira Jéssyca E. S. , Silva Alfredo J. F. , Nascimento Paula F. P. , Ferreira Ruan L. S. , Barros Neto Eduardo L. 
Published: October 2020

Abstract
In this work, the natural and modified carnauba powder from the addition of bentonite was evaluated for the adsorption of Cu(II) ions in synthetic solution. The results showed that the carnauba powder treated with bentonite (CPTB) showed a better percentage of removal of Cu(II) ions when compared to natural carnauba powder (NCP). The best results for both adsorbents were obtained with pH 5. The adsorption kinetics was governed by the pseudo-second-order model for both bioadsorbents studied. While the isothermal behavior was governed by the Langmuir model and showed that the adsorption capacity of the CPTB for Cu(II) was 21.98 mg·g−1. The interaction of the metal and CPTB was also investigated by means of thermodynamic parameters showing that the adsorption process is not spontaneous, although the values of ΔG° decrease with the increase in temperature from 20 to 40 °C and endothermic causing an increase in the degree of disorder at the solid/liquid interface. The results showed that the CPTB is a material with potential adsorbent for the removal of copper ions.
Conservative Management of Gestational Hypercalcemia Due to Primary Hyperparathyroidism with Lack of Complications
Authors: Di Bari Flavia , Vita Roberto , Marini Herbert , Borrielli Irene , Lo Re Carmela , Panebianco Vincenzo , Benvenga Salvatore 
Published: October 2020

Introduction:
Primary hyperparathyroidism (PHPT) is rare in pregnancy. PHPT and hypercalcemia
are associated with negative maternofetal outcomes. Therefore, an early diagnosis and
adequate treatment are essential.

Case Presentation:
We described the case of a pregnant woman complaining of nausea, vomiting
and weight loss. Diagnosis of gestational PHPT (GPHPT) was made based on elevated serum calcium
and parathyroid hormone levels (3.4 mmol/L and 41.6 pmol/L). Neck ultrasound documented a
nodule suggestive of enlarged parathyroid, whereas the abdomen ultrasound revealed renal microlithiasis.
Conservative treatment was started with oral hydration and a low-calcium diet. Clinical
and biochemical monitoring was weekly and multidisciplinary. Despite our suggestion, the patient
refused parathyroidectomy in the second trimester. Additional intravenous fluid rehydration
from the 15th to the 25th week of gestation ameliorated the symptoms rapidly, and reduced calcium
levels progressively from the 23rd week. At week 40, the woman gave birth to a healthy girl. At
month 8 postpartum, calcemia and PTH were still elevated, and accompanied by osteoporosis and
nephrocalcinosis. Surgery was accepted, and a parathyroid adenoma was removed.

Conclusion:
In the absence of guidelines for GPHPT management, its treatment should be individualized.
In our case, despite high calcium levels, conservative treatment with strict monitoring led
to a positive outcome of pregnancy.
Development of an Item Bank to Measure Medication Adherence: Systematic Review
Authors: Kwan Yu Heng , Oo Livia Jia Yi , Loh Dionne Hui Fang , Phang Jie Kie , Weng Si Dun , Blalock Dan V , Chew Eng Hui , Yap Kai Zhen , Tan Corrinne Yong Koon , Yoon Sungwon , Fong Warren , Østbye Truls , Low Lian Leng , Bosworth Hayden Barry , Thumboo Julian 
Published: October 2020

Background
Medication adherence is important in managing the progression of chronic diseases. A promising approach to reduce cognitive burden when measuring medication adherence lies in the use of computer‐adaptive tests (CATs) or in the development of shorter patient-reported outcome measures (PROMs). However, the lack of an item bank currently hampers this progress.

Objective
We aim to develop an item bank to measure general medication adherence.

Methods
Using the preferred reporting items for systematic review and meta-analysis (PRISMA), articles published before October 2019 were retrieved from PubMed, Embase, CINAHL, the Cochrane Library, and Web of Science. Items from existing PROMs were classified and selected (“binned” and “winnowed”) according to standards published by the Patient-Reported Outcomes Measurement Information System (PROMIS) Cooperative Group.

Results
A total of 126 unique PROMs were identified from 213 studies in 48 countries. Items from the literature review (47 PROMs with 579 items for which permission has been obtained) underwent binning and winnowing. This resulted in 421 candidate items (77 extent of adherence and 344 reasons for adherence).

Conclusions
We developed an item bank for measuring general medication adherence using items from validated PROMs. This will allow researchers to create new PROMs from selected items and provide the foundation to develop CATs.
Associations Between COVID-19 Misinformation Exposure and Belief With COVID-19 Knowledge and Preventive Behaviors: Cross-Sectional Online Study
Authors: Lee Jung Jae , Kang Kyung-Ah , Wang Man Ping , Zhao Sheng Zhi , Wong Janet Yuen Ha , O'Connor Siobhan , Yang Sook Ching , Shin Sunhwa 
Published: October 2020

Background
Online misinformation proliferation during the COVID-19 pandemic has become a major public health concern.

Objective
We aimed to assess the prevalence of COVID-19 misinformation exposure and beliefs, associated factors including psychological distress with misinformation exposure, and the associations between COVID-19 knowledge and number of preventive behaviors.

Methods
A cross-sectional online survey was conducted with 1049 South Korean adults in April 2020. Respondents were asked about receiving COVID-19 misinformation using 12 items identified by the World Health Organization. Logistic regression was used to compute adjusted odds ratios (aORs) for the association of receiving misinformation with sociodemographic characteristics, source of information, COVID-19 misinformation belief, and psychological distress, as well as the associations of COVID-19 misinformation belief with COVID-19 knowledge and the number of COVID-19 preventive behaviors among those who received the misinformation. All data were weighted according to the Korea census data in 2018.

Results
Overall, 67.78% (n=711) of respondents reported exposure to at least one COVID-19 misinformation item. Misinformation exposure was associated with younger age, higher education levels, and lower income. Sources of information associated with misinformation exposure were social networking services (aOR 1.67, 95% CI 1.20-2.32) and instant messaging (aOR 1.79, 1.27-2.51). Misinformation exposure was also associated with psychological distress including anxiety (aOR 1.80, 1.24-2.61), depressive (aOR 1.47, 1.09-2.00), and posttraumatic stress disorder symptoms (aOR 1.97, 1.42-2.73), as well as misinformation belief (aOR 7.33, 5.17-10.38). Misinformation belief was associated with poorer COVID-19 knowledge (high: aOR 0.62, 0.45-0.84) and fewer preventive behaviors (≥7 behaviors: aOR 0.54, 0.39-0.74).

Conclusions
COVID-19 misinformation exposure was associated with misinformation belief, while misinformation belief was associated with fewer preventive behaviors. Given the potential of misinformation to undermine global efforts in COVID-19 disease control, up-to-date public health strategies are required to counter the proliferation of misinformation.