bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of growth conditions on β-glucosidase production by local isolate of Aspergillus niger using rice bran substrate
Authors: Sugiwati Sri , Hanafi Muhammad , Lioe Hanifah , Suhartono Maggy 
Published: September 2020

Abstract. Sugiwati S, Hanafi M, Lioe HN, Suhartono MT. 2020. Effect of growth conditions on β-glucosidase production by local isolate of Aspergillus niger using rice bran substrate. Biodiversitas 21: 4058-4066. β-Glucosidase is the family of glycosyl hydrolase that have potential role in various food industry, such as in tea, wine and vanilla industries to increase the aroma and production of isoflavone aglycons in soybean flour. The present work produced β-glucosidase from local isolate of Aspergillus niger InaCC F57 under solid-state fermentation (SSF) using rice bran substrate. Fermentation process was made in various conditions with respect to carbon source as substrate, initial pH of fermentation medium, incubation time, water to substrate ratio, fermentation temperature, and addition of Mandels mineral salts solution. The results showed that activity of β-glucosidase was best at, i.e., 2.45 U/mL, with the use of rice bran as substrate. Furthermore, optimum condition for the highest production of β-glucosidase occurred at pH 2.0, incubation time of 5 days, water to substrate ratio of 1.5: 1, and incubation temperature of 32°C. Additionally, in optimum fermentation conditions, production of β-glucosidase could be enhanced up to 26.22% with the presence of Mandels mineral salts solution as compared to the control.
Potentially lactic acid bacteria as an EPS producing starter from yellow sweet potato fermentation
Authors: YULIANA NETI , SUMARDI Sumardi , JATMIKO EDO , ROSALINE MENTARI , IQBAL MUHAMMAD 
Published: September 2020

Potentially lactic acid bacteria as a starter for EPS production from yellow sweet potato fermentation were determined. The fermentation profile and partial characteristics of isolated lactic acid bacteria were used as considerations. The fermentation of yellow sweet potato was performed in the back-slopping and spontaneous procedure and was paid attention to the hours of 0, 24, 48, and 72. The results showed that the 72 hours of fermentation was found to have the highest EPS metabolites, the number of a LAB, the total lactic acid, and the lowest pH. The 72 hours of fermentation also seemed to cause a significant change in the sweet potato starch granules morphology. The potential starter, therefore, can be taken from the yellow sweet potato fermentation either spontaneously or by a back-slopping method, at 72 hours. From the sixty selected LAB, the 34 strains showed an ability to produce EPS. Among these, eight strains exhibited the potential high production of EPS. They were capable of growth on 28-45C and exhibited tolerance to 3-4% NaCl. The favorable carbon sources for the growth and production of EPS were isolated dependent.
Embedded Digital Twins in future energy management systems: paving the way for automated grid control
Authors: Brosinsky Christoph , Krebs Rainer , Westermann Dirk 
Published: September 2020

Abstract
Emerging real-time applications in information technology, and operational technology enable new innovative concepts to design and operate cyber-physical systems. A promising approach, which has been discovered recently as key technology by several industries is the Digital Twin (DT) concept. A DT connects the virtual representation of a physical object, system or process by available information and sensor data streams, which allows to gather new information about the system it mirrors by applying analytic functions. Thereby the DT technology can help to fill sensor data gaps, e. g., to support anomaly detection, and to predict future operating conditions and system states. This paper discusses a dynamic power system DT as a cornerstone instance of a new generation of EMS, and a prospective new EMS architecture, to support the increasingly complex operation of electric power systems. Unlike in traditional offline power system models, the parameters are updated dynamically using measurement information from the supervisory control and data acquisition (SCADA) and a wide area monitoring system (WAMS) to tune the model. This allows to derive a highly accurate virtual representation of the mirrored physical objects. A simulation engine, the Digital Dynamic Mirror (DDM) is introduced, in order to be able to reproduce the state of a reference network in real-time. The validation of the approach is carried out by a case study. In a closed loop within EMS applications, the DDM can help to assess contingency mitigation strategies, thus it can support the decision-making process under variable system conditions. The next generation of control centre Energy Management System (EMS) can benefit from this development by augmentation of the dynamic observability, and the rise of operator situation awareness.
Minimum retesting intervals in practice: 10 years experience
Authors: Lang Tim 
Published: September 2020

Abstract

Background
Minimum retesting intervals (MRI) are a popular demand management solution for the identification and reduction of over-utilized tests. In 2011 Association of Clinical Biochemistry and Laboratory Medicines (ACB) published evidence-based recommendations for the use of MRI.

Aim
The aim of the paper was to review the use of MRI over the period since the introduction of these recommendations in 2011 to 2020 and compare it to previous published data between 2000-2010.

Methods
A multi-source literature search was performed to identify studies that reported the use of a MRI in the management or identification of inappropriate testing between the years prior to (2000–2010) and after implementation (2011–2020) of these recommendations.

Results
31 studies were identified which met the acceptance criteria (2000–2010 n=4, 2011–2020 n=27). Between 2000 and 2010 4.6% of tests (203,104/4,425,311) were identified as failing a defined MRI which rose to 11.8% of tests (2,691,591/22,777,288) in the 2011–2020 period. For those studies between 2011 and 2020 reporting predicted savings (n=20), 14.3% of tests (1,079,972/750,580) were cancelled, representing a total saving of 2.9 M Euros or 2.77 Euro/test. The most popular rejected test was Haemoglobin A1c which accounted for nearly a quarter of the total number of rejected tests. 13 out 27 studies used the ACB recommendations.

Conclusions
MRI are now an established, safe and sustainable demand management tool for the identification and management of inappropriate testing. Evidence based consensus recommendations have supported the adoption of this demand management tool into practice across multiple healthcare settings globally and harmonizing laboratory practice.
Comparison of acetylsalicylic acid and clopidogrel non-responsiveness assessed by light transmittance aggregometry and PFA-100® in patients undergoing neuroendovascular procedures
Authors: Rolling Christina C. , Tomada Julia , Frölich Andreas M. , Holst Brigitte , Holstein Katharina , Voigtländer Minna , Janjetovic Snjezana , Haddad Munif , Renné Thomas , Fiehler Jens , Bokemeyer Carsten , Rolling Thierry , Langer Florian 
Published: September 2020

Abstract

Objectives
Dual platelet inhibition is commonly used for prevention of cardiovascular events in patients undergoing neuroendovascular procedures. Non-responsiveness to platelet inhibitors may be associated with adverse outcomes. The aim of this study was to evaluate the reliability of the platelet function analyzer PFA-100® in comparison to light transmittance aggregometry (LTA) for monitoring clopidogrel and acetylsalicylic acid (ASA) non-responsiveness in a cohort of patients treated for intracranial aneurysm or cranial artery stenosis.

Methods
Non-responsiveness to clopidogrel and ASA was assessed by LTA using adenosine diphosphate (ADP) and arachidonic acid and by PFA-100® with the ADP/prostaglandin E1 (PGE1) and collagen/epinephrine cartridges, respectively.

Results
A total of 203 patients (145 females; median age, 57 years) were analyzed. Agreement between the two tests was poor for clopidogrel non-responsiveness (ƙ=0.19) and not better than chance for ASA non-responsiveness (ƙ=0.01). Clopidogrel non-responsiveness by LTA and PFA-100® was associated with higher von Willebrand factor antigen and activity levels. ADP-induced platelet disaggregation was lower in patients with clopidogrel non-responsiveness as assessed by PFA-100®. Clopidogrel non-responsiveness by LTA was associated with a higher prevalence of diabetes and a higher body mass index (BMI). Adverse outcomes (death, thromboembolism, or in-stent thrombosis) occurred in 13% (n=26) of all patients independently of ASA and clopidogrel non-responsiveness as assessed by both devices.

Conclusions
Our results show that LTA and PFA-100® are not interchangeable in the assessment of ASA and clopidogrel non-responsiveness in patients undergoing neuroendovascular interventions.
Sulfur application alleviates chromium stress in maize and wheat
Authors: Kulczycki Grzegorz , Sacała Elżbieta 
Published: September 2020

AbstractThis study aimed to examine the influence of increasing doses of chromium (Cr) (26, 39, and 52 mg kg−1soil) and elemental sulfur (S) (60 mg kg−1soil) on growth, yield, and mineral nutrition in wheat and maize. Macro- and micronutrients and Cr concentrations were determined in the aboveground parts of plants. All examined doses of Cr caused a marked decrease in the fresh and dry weight of maize. Wheat was more tolerant than maize, and lower Cr doses caused a small but statistically significant increase in the total yield. Wheat accumulated more than twofold Cr than maize, and the concentrations increased with higher Cr concentrations in the soil. The application of S significantly improved the total biomass production and lowered the Cr content in both plants. Cr changed the mineral nutrition in both cereals, but the pattern of changes observed was not the same. Applying S alleviated some adverse effects caused by the Cr. Hence, it is concluded that the application of elemental S may be an effective strategy to reduce adverse effects in plants grown on soil contaminated by heavy metals, especially Cr.
Note on Dolbeault cohomology and Hodge structures up to bimeromorphisms
Authors: Angella Daniele , Suwa Tatsuo , Tardini Nicoletta , Tomassini Adriano 
Published: September 2020

AbstractWe construct a simply-connected compact complex non-Kähler manifold satisfying the ∂ ̅∂ -Lemma, and endowed with a balanced metric. To this aim, we were initially aimed at investigating the stability of the property of satisfying the ∂ ̅∂-Lemma under modifications of compact complex manifolds and orbifolds. This question has been recently addressed and answered in [34, 39, 40, 50] with different techniques. Here, we provide a different approach using Čech cohomology theory to study the Dolbeault cohomology of the blowup ̃XZ of a compact complex manifold X along a submanifold Z admitting a holomorphically contractible neighbourhood.
Age differences in preferences for emotionally-meaningful versus knowledge-related appeals
Authors: van der Goot Margot J. , Bol Nadine , Weert Julia C. M. van 
Published: September 2020

Abstract
Socioemotional selectivity theory (SST), an influential life-span theory, suggests that older adults prefer persuasive messages that appeal to emotionally-meaningful goals over messages that appeal to knowledge-related goals, whereas younger adults do not show this preference. A mixed-factorial experiment was conducted to test whether older adults (≥65 years) differ from younger adults (25–45 years) in their preference for emotionally-meaningful appeals over knowledge-related appeals, when appeals are clearly developed in line with SST. For older adults we found the expected preference for emotionally-meaningful appeals for cancer centers but not for grocery stores and travel organizations. As expected, in most cases, younger adults did not show a preference. Implications for SST-based communication research and for practice are discussed.
Brazilian laboratory indicators benchmarking program: three-year experience on pre-analytical quality indicators
Authors: Shcolnik Wilson , Berlitz Fernando , Galoro Cesar Alex de O. , Biasoli Vinicius , Lopes Rafael , Jerônimo Diogo , Balli Luiza Bottino , Bernardes Leticia H. 
Published: September 2020

Abstract

Objectives
In the laboratory medicine segment, benchmarking is the process in which institutions seek to compare with the macro environment (performance comparison and best practices with different laboratories) and improve their results based on quality indicators. The literature has highlighted the vulnerability of the pre-analytical phase in terms of risks and failures and the use of interlaboratory comparison as an opportunity to define a strategic performance benchmark aligned with the laboratory medicine sector, which has been a promising strategy to ensure continuous improvement, identifying within the pre-analytical process the critical activities to guarantee patient safety. In this context, this paper aims to present the three-year experience (2016–2018) of the Benchmarking Program and Laboratory Indicators – in Portuguese, Programa de Benchmarking e Indicadores Laboratoriais (PBIL) – with emphasis on pre-analytical indicators and their comparison against literature references and other programs of benchmarking in the area of laboratory medicine. PBIL is organized by the Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) in conjunction with Controllab and coordinated by a Brazilian group with representatives from different countries.

Methods
The data presented in this paper involving the performance results of 180 laboratories with active participation. Results are presented in percentage (%, boxplot graphical in quartiles) and Sigma metric, recognized as the metric that best indicates the magnitude of failures in a process. The Pareto Chart was used to facilitate ordering and to identify the main errors in the pre-analytical phase. The Radar Chart was made available in this work for the purpose of comparing the results obtained in Sigma by the PBIL and IFCC Working Group Laboratory Errors and Patient Safety (WG LEPS).

Results
In the study period, just over 80% of the pre-analytical failures are related to Blood culture contamination (hospital-based and non-hospital-based laboratories), Recollect and Non-registered exams, with failure rates of 2.70, 1.05 and 0.63%, respectively. The performance of the PBIL program participants was in line with the literature references, and allowed to identify benchmarks in the laboratory medicine market, target of PBIL, with best practices were observed for some indicators.

Conclusions
The results of the program demonstrate the importance of an ongoing program comparative performance-monitoring program for setting more robust goals and consequently reducing laboratory process failures. Even with these promising premises and results, the contextualized analysis of the program indicators, point to a still significant number of failures in our market, with possibilities for improvement in order aiming to ensure more robust and effective processes.
Modeling the incidence and death rates of COVID-19 pandemic in different regions of the world
Authors: de Oliveira Ricardo Puziol , Achcar Jorge Alberto , Nunes Altacílio Aparecido 
Published: September 2020

AbstractThis paper reports a broad study using epidemic-related counting data of COVID-19 disease caused by the novel coronavirus (SARS-CoV-2). The considered dataset refers to 119 countries’ daily counts of reported cases and deaths in a fixed period. For the data analysis, it has been adopted a beta regression model assuming different regions of the world where it was possible to discover important economic, health and social factors affecting the behavior of the pandemic in different countries. The Bayesian method was applied to fit the proposed model. Some interesting conclusions were obtained in this study, which could be of great interest to epidemiologists, health authorities, and the general public in the face of the forthcoming hard times of the global pandemic.
Improved high-temperature damping performance of nitrile-butadiene rubber/phenolic resin composites by introducing different hindered amine molecules
Authors: Song Meng , Yue Xiulin , Wang Xiujuan , Huang Mengjie , Ma Mingxing , Pan Wei , Qin Qi 
Published: September 2020

Abstract
By introducing hindered amine GW-622 or GW-944 into nitrile-butadiene rubber/phenolic resin (NBR/PR, abbreviated as NBPR) matrix, we have prepared different hindered amine/NBR/PR ternary hybrid damping materials with high-temperature damping performance, respectively. Fourier transform infrared (FTIR) spectroscopy, scanning electron microscope (SEM), differential scanning calorimetry (DSC), and dynamic thermomechanical analysis (DMA) were used to research the microstructure, compatibility, and damping properties of the hindered amine/NBPR composites. FTIR results indicate that hydrogen bonds are formed between the hindered amine and the NBPR matrix. Both DSC and SEM results show that hindered amine has partial compatibility with the NBPR matrix. DMA results show that two loss peaks appear in the hindered amine/NBPR composite. Thereby, the composites show better damping performance at a higher temperature, and the temperature domain of high-temperature damping becomes wider with the increase in the addition of hindered amine. This study provides a theoretical support for the preparation of high-temperature damping materials.
A novel biofabrication of gold nanoparticles using Erythrina senegalensis leaf extract and their ameliorative effect on mycoplasmal pneumonia for treating lung infection in nursing care
Authors: Yu Hong , Mu Yingmei , Mu Lianzhi 
Published: September 2020

AbstractThis study showed the fabrication of gold nanoparticles (AuNPs) utilizing Erythrina senegalensis leaf extract as an effective, low-cost and eco-friendly approach. The bioconstituents existing in the E. senegalensis leaf extract are accountable for reducing and stabilization of NPs. The produced AuNPs were studied by using transmission electron microscopy, X-ray diffraction, UV-visible (UV-Vis) spectroscopy, Fourier transform infrared spectroscopy and energy-dispersive X-ray spectroscopy. In addition, this study also showed that the prepared AuNPs exhibited very good antipneumonial activity against mycoplasmal pneumonia in the investigational animals, indicating their potential for the development of new therapeutic drugs for the lung injury treatments in in the future.
Enhancing the mechanical and water resistance performances of bamboo particle reinforced polypropylene composite through cell separation
Authors: Ren Dan , Zhang Xuexia , Yu Zixuan , Wang Hankun , Yu Yan 
Published: September 2020

Abstract
It is frequently observed that bamboo particle composites (BPCs) do not show higher mechanical performances than the corresponding wood particles composites (WPCs), although bulk bamboo is much stronger than wood in mechanical performances. Herein this phenomenon was demonstrated from the cell compositions in the applied bamboo particles. To address that, a simple method to physically separate bamboo fibers (BFs) and bamboo parenchyma cells (BPs) from a bamboo particle mixture was developed. Polypropylene (PP) composites with pure BFs, BPs, a mixture of BFs and BPs (BFs + BPs), wood particles (WPs) as fillers were prepared. The flexural and dynamic mechanical properties, water absorption, and thermal properties were determined. The BF/PP composites showed the best mechanical performances (MOR at 35 MPa, MOE at 2.4 GPa), followed by WP/PP, (BF + BP)/PP, and BP/PP. They also exhibited the lowest water absorption and thickness swelling. Little difference was found for the thermal decomposition properties. However, a lower activation energy of BF/PP compared with BP/PP implied an uneven dispersion of BFs and weaker interfacial interaction between BF and PP. The results suggest that the mechanical performances and water resistance of bamboo particle/polymer composites can be significantly improved through cell separation. However, interface modification should be applied if higher performances of BF/PP composites are required.
Decay, insect, and termite resistance of wood modified with epoxidized vegetable oils
Authors: Kose Demirel Gaye , Temiz Ali , Palanti Sabrina , Terziev Nasko 
Published: September 2020

Abstract
Samples of Scots pine sapwood were treated with epoxidized linseed and soybean oils to improve decay, insect and termite resistance of wood. Non-epoxidized (raw) linseed and soybean oils were included as reference treatment in the study. In the epoxidation process, hydrogen peroxide was used to open double bounds, and acetic acid was added as a catalyst. Two retention levels, Ret A (80–140 kg m−3) and Ret B (170–270 kg m−3), two impregnation methods (full cell and empty cell) and emulsion technique were used. Samples treated with epoxidized oils had significantly lower mass losses than untreated samples while epoxidized oils showed higher mass losses than unepoxidized oils for Coniophora puteana and Trametes versicolor according to EN 113 for decay test. By adding boron, fungicidal properties were introduced to the treatment. All the vegetable oils showed 100% the mortality rate against larvae of Hylotrupes bajulus according to EN 47. Moreover, leached wood samples treated with oils also showed 100% larvae mortality. Additionally, termite testing based on EN 117 revealed 100% Reticulitermes lucifugus mortality for all leached oil treated samples.
Taking a joke seriously: When does humor affect responses to the slurring of people with intellectual disabilities?
Authors: Katz Jennifer , Wing-Paul Dimitri 
Published: September 2020

AbstractThe use of humor may affect how bystanders respond to slurs. Undergraduates (N = 192) completed a measure of prejudice towards people with intellectual disabilities and were randomly assigned to read a scenario in which a peer uses a slur either as part of a joke (humor condition) or a statement (control condition). Participants responded to measures of intent to assertively respond and their evaluation of the speaker. Humor inhibited intent to nonverbally disagree and to verbally confront. Bystanders’ own prejudicial attitudes moderated the effects of humor on intent to verbally confront and negative evaluation. In the humor condition, compared to those with lower prejudice, those with higher prejudice showed less intent to confront and less negative evaluations. In the control condition, intent to confront, and negative evaluation were high, regardless of prejudice. These results suggest that humor inhibits assertive responses to slurs, particularly among people without highly favorable attitudes about the targeted social group.
Determinants of waterpipe smoking among high school students in Jakarta, Indonesia
Authors: Fauzi Ridhwan , Areesantichai Chitlada 
Published: September 2020

Abstract

Objectives
The study aimed to examine factors associated with past 30 days waterpipe use among high school students in Jakarta, Indonesia.

Methods
We surveyed a multistage cluster random sample of 1,318 students of grade 10th and 11th from 14 schools in Jakarta. Multiple logistic regressions were employed to examine the association between past 30 days waterpipe use with sociodemographic characteristics, cigarettes smoking status, parental and peer use, availability and affordability.

Results
Of 1,318 participants, 3.3% of female and 8.4% of male currently smoked waterpipe. Multivariate analysis revealed that current waterpipe use was significantly associated with family use (AOR: 4.844, 95% CI: 1.225–19.151), friend use (AOR: 2.554, 95% CI: 1.424–4.582), and availability (AOR: 2.143, 95% CI: 1.127–4.076). Being current smokers were six times more likely (AOR: 6.055, 95% CI: 3.123–11.739) to use waterpipe in the past 30 days.

Conclusions
The finding suggests that smoking by a family member, friends, use of conventional cigarettes, and availability are significantly associated with increased probability of current waterpipe used among adolescents.