bluuebunny/crossref_metadata_2025_split huggingface dataset:
miR-142-3p suppresses apoptosis in spinal cord-injured rats
Authors: Zheng Jun , Kuang Jing , Zhang Xianyu , Luo Daya , Liao Weijing 
Published: May 2020

Abstract

Introduction
Spinal cord injury (SCI) leads to abnormal expression of miRs, leading to secondary responses such as oxidative stress, inflammation and apoptosis. In the present work, we screened the miRs involved and the associated pathway.

Methods
In a rat model of SCI, the microarray analysis for expression of miRs at various time points post-SCI was done. The locomotor analysis was done by Basso, Beattie and Bresnahan score, and Cresyl violet staining was done for lesion volume and TUNEL assay was done for apoptosis in neuronal cells. The expression of apoptotic proteins was done by the western blot study.

Results
It was evidenced that the expression of the number of miRs was altered on the 14th day post-SCI, and miR-142-3p was found to be the most significantly suppressed miR. The results suggested that overexpression of miR-142-3p by its agomir-attenuated functional recovery decreased lesion size and apoptosis of neuronal cells in rats subjected to SCI. The luciferase assay indicated that miR-142-3p blocked the levels of Bax, which is a significant activator of the mitochondrial apoptotic pathway (MAP) via targeting the 3′UTR region of BV-2 cells, and in addition, pc-DNA-Bax restored Bax and inhibited the correcting role of miR-142-3p in hydrogen peroxide-treated BV-2 cells. The findings suggested that miR-142-3p may inhibit the MAP by inhibiting the expression of cleaved-caspase-3/-9 and Bax in SCI rats.

Conclusion
This study concludes that miR-142-3p may attenuate the functional recovery and decrease apoptosis in neuronal cells via inhibiting the MAP in the spinal cord-injured rats, confirming miR-142-3p as a potential therapeutic target in treating SCI.
On the Justifications of Contemporary Global Justice Theories
Authors: Zhehan Li 
Published: May 2020

Abstract
Contemporary global justice theories could be introduced and reduced to three kinds: the deontological approach, the theory of obligation, and the theory of self-interest. Our analysis finds that only the theory of obligation and the theory of self-interest provide strong enough justifications for developed states and their people to assist underdeveloped states and their people. However, the theory of obligation requires some special preconditions, and the theory of self-interest cannot proceed in the name of justice, so we conclude that contemporary global justice theories are not tenable.
Political Reconciliation in Light of Global Injustices
Authors: Hahn Henning 
Published: May 2020

Abstract
This article applies the idea of political reconciliation (and with it the rationale of restorative justice) to current debates on global injustices. My underlying thesis is that the idea of reconciliation fits better to the nonideal circumstances of global exploitation and domination. Originally, political reconciliation defines a transitional process from a state of severe injustice to a state of renewed social peace and cooperation under conditions of serious disagreement and in the absence of a well-ordered social structure. What the theory of political reconciliation has to add to nonideal theorizing is that political stability and unity (both domestically and globally) are to be based on a societal healing process that depends on institutional measures of trust-building, truth telling and forgiveness.
The Openness of Life-world and the Intercultural Polylogue
Authors: Jun Wang 
Published: May 2020

Abstract
The phenomenological conception of “life-world” lays the theoretical foundation for the openness of the world. The founding relationship between the individual and the world, the interactive relationship among different cultural worlds on the intersubjective level, the free nature of truth and its presence in the open world, the “ek-sistent” characteristics of the human-being, the structural constitution of the life-world – all these topics demonstrate the open nature of the world in a phenomenological way. Based on these ideas, “reflective judgment” as “phronesis” and “fear” as ethic sentiment based on family experience become the practical stance, which is consistent with the “life-world” conception of phenomenology; the characteristics of publicness and intersubjectivity of the open world are thus maintained. In the face of the multicultural world, this attitude presents as a brand-new practice of intercultural philosophy, which is different from the centralism found under the framework of monism and the comparative philosophy under the framework of dualism. Such a practice of intercultural philosophy is “polylog”, i.e. based on the principles of difference and equality and searching for the “overlapping consensus” in full multi-participatory discussion. Through polylog, a harmonious life of human community is constructed. This paper attempts to derive a set of practical principles for maintaining the openness of the world and intercultural polylog in the era of globalization from the theoretical view of the phenomenological life-world.
Compulsive Growth and the Dynamics of “Perverted Progress”
Authors: Markow Jekaterina 
Published: May 2020

AbstractThis text offers a critique of a certain development in political discourses on progress, namely the “decoupling” of notions of moral from notions of technological progress. This decoupling yields fatal social, economic and ecologic consequences in practice that ultimately amount to a virtual perversion of progress. The second part of the paper reflects upon the psychosocial drivers of this dynamic. I venture that the only motive that may explain why we reproduce this dynamic even as we increasingly suffer from its consequences is a compulsive avoidance of limitation, i.e. non-satisfaction of needs. Finally, I offer some tentative suggestions as to what a mature approach towards limitation would entail.
Subjekt und Person: Zwei Selbst-Bilder des modernen Menschen in kulturübergreifender Perspektive
Authors: Tze-wan Kwan 
Published: May 2020

Abstract
Die beiden Begriffe „Subjekt“ und „Person“ repräsentieren zwei verschiedene Weisen, wie der abendländische Mensch zum Verständnis seines eigenen „Selbst“ gelangt. Während „Subjekt“ auf eine Selbstzentrierung hindrängt, bedeutet „Person“ von Anfang an eine „selbst-lose“ Einfühlung in den Anderen. Nach der Explikation dieser beiden Schlüsselbegriffe sollen einige weiterführende Reflexionen auf das Problem des „Selbst“ aus der Sicht der chinesischen Philosophie sichtbar machen, wie das Problem von einer post-europäischen Perspektive aus betrachtet werden kann.
Bahnhof und Dom in Köln
Authors: Auffarth Christoph 
Published: May 2020

ZusammenfassungDurch Aufklärung und Französische Revolution angestoßen, suchte der Umbruch in die Moderne des 19. Jahrhunderts nach einem neuen Verständnis von Sakralität und überlieferten Religionen. Kunstreligion und Nationalreligion sind Formen. Sie können als Widerspruch zu Religion dienen, aber häufiger werden sie integriert. Am Fall der Vollendung des Kölner Doms als Akteur einermaterial religionin der Nachbarschaft mit anderen nicht-sakralen Gebäuden (hier der Bahnhof und die Brücke) nimmt der Aufsatz Konzepte desspatial turnauf. Für eine vollständige Analyse der Konfiguration ist aber die Wahrnehmung (Aisthesis/Synästhetik, hier in der Bewegung der Eisenbahnfahrt und des Übergangs am Bahnhof) und Deutungshoheit der Akteure in einer kolonialen Konfiguration unabdingbar: die Religionsästhetik als verknüpfende Methode (A. Grieser).
Sequenzanalytische Bildhermeneutik und religionswissenschaftliche Atmosphärenforschung
Authors: Radermacher Martin 
Published: May 2020

ZusammenfassungSowohl in religiöser als auch in analytischer Sprache wird der Begriff „Atmosphäre“ regelmäßig verwendet, ohne bisher jedoch systematische Aufmerksamkeit seitens der Forschung zu erfahren. Dennoch ist die Religionswissenschaft inzwischen vorbereitet auf eine Diskussion und Entwicklung dieses Konzeptes, hat sie doch in verschiedenen Perspektivenwechseln der letzten Jahrzehnte wesentliche Aspekte dessen erforscht, was Atmosphären ausmacht. Dieser Beitrag schlägt einen methodischen Baustein vor, der eine Dimension von Atmosphären – nämlich das sozialräumliche Arrangement selbst – zu untersuchen vermag. Dieser sequenzanalytisch orientierte Baustein wird beispielhaft auf einen konkreten, fotografisch protokollierten Fall angewendet, ohne damit die Notwendigkeit weiterer methodischer Verfahren in Frage zu stellen.
The politicization of research methods, illustrated in the case of plant closures
Authors: Weller Sally A. 
Published: May 2020

AbstractThis paper contributes to building better methods in economic geography by examining the coevolution of theory, methodology, and should read methodology, and the practice of research methods with the policy context. The paper suggests that debates about how economic geography defines its theoretical and methodological boundaries have not been sufficiently cognizant of the effects of policy engagement. It posits that the politicized contemporary context is aligning research practices to policy constituencies, reshaping research questions, altering the criteria of research validity, increasing the division between qualitative and quantitative approaches, and solidifying divisions between different sub-branches of the discipline. This process is illustrated by way of a genealogy of studies of plant closures. The conclusion links these changes to questions about the future of the discipline.
Heuristische Textpraktiken in den Wissenschaften
Authors: Bender Michael , Müller Marcus 
Published: May 2020

Abstract
This article contains a comparative study of heuristic textual practices in various scientific disciplines. By this we mean formulation practices with which new knowledge is generated in institutionally influenced routines and connected to existing knowledge, e. g. ‚highlighting the relevance of a research topic‘, ‚defining a concept‘ or ‚supporting a statement argumentatively‘.
The aim is to find out to what extent such textual practices occur in different scientific disciplines, how they are distributed and combined. Furthermore, we study the effects domain-specific contexts have on heuristic textual practices. The data basis of our study is a corpus of 65 dissertations from the 13 different faculties of the TU Darmstadt. In the pilot study we report here, we examined the introductory chapters of the dissertations. Methodologically, it is an annotation study: Based on the current state of research on the subject, we have derived a basic annotation scheme, which we have developed and refined in a collaborative process of guideline creation. Our study affiliates on socio-pragmatic research on text production and formulation routines in the sciences. It is theoretically informed by the philosophy of science research on heuristics, methodically we make a contribution to the scientific debate on collaborative annotation procedures.
Synthesis and crystal structures of two layered Cu(I) and Ag(I) iodidometalates
Authors: Dehnhardt Natalie , Berthold Chantsalmaa , Dollberg Kevin , Tambornino Frank , Heine Johanna 
Published: May 2020

Abstract
Cu(I) and Ag(I) iodidometalates have been investigated for both their rich structural chemistry, as well as for useful properties like luminescence. Here, we present the synthesis and crystal structure of (BzA)[MI2] · 0.5 H2O (BzA = benzylammonium; M=Cu (1), Ag (2)). The two compounds are isostructural and show a previously unknown layered anion motif that can be described as a 44 net constructed via corner-sharing of M2I6 subunits, built from two edge-sharing MI4 tetrahedra.
Alkaline earth metal ordering in CaCu9Mg2 and SrCu9Mg2
Authors: Reimann Maximilian K. , Pöttgen Rainer 
Published: May 2020

Abstract
The copper-rich intermetallic compounds CaCu9Mg2 and SrCu9Mg2 were synthesized by induction melting of the elements and subsequent annealing in a muffle furnace. CaCu9Mg2 and SrCu9Mg2 crystallize with the TbCu9Mg2 type structure, space group P 63/mmc, which is a ternary ordered variant of CeNi3. The polycrystalline samples were characterized through their X-ray powder patterns. The CaCu9Mg2 structure was refined from single-crystal X-ray diffraction data. a = 504.13(9), c = 1622.5(3) pm, wR2 = 0.0635, 302 F2 values and 19 variables. The two striking coordination polyhedra in the CaCu9Mg2 structure are Ca@Cu18Mg2 and Mg@Cu12Mg3Ca. These polyhedra condense to layers which are stacked in ABA′B′ sequence. The X-ray data give no hint for Ca/Mg mixing.
Selected applications of typicality to real-time dynamics of quantum many-body systems
Authors: Heitmann Tjark , Richter Jonas , Schubert Dennis , Steinigeweg Robin 
Published: May 2020

Abstract
Loosely speaking, the concept of quantum typicality refers to the fact that a single pure state can imitate the full statistical ensemble. This fact has given rise to a rather simple but remarkably useful numerical approach to simulate the dynamics of quantum many-body systems, called dynamical quantum typicality (DQT). In this paper, we give a brief overview of selected applications of DQT, where particular emphasis is given to questions on transport and thermalization in low-dimensional lattice systems like chains or ladders of interacting spins or fermions. For these systems, we discuss that DQT provides an efficient means to obtain time-dependent equilibrium correlation functions for comparatively large Hilbert-space dimensions and long time scales, allowing the quantitative extraction of transport coefficients within the framework of, e. g., linear response theory (LRT). Furthermore, it is discussed that DQT can also be used to study the far-from-equilibrium dynamics resulting from sudden quench scenarios, where the initial state is a thermal Gibbs state of the pre-quench Hamiltonian. Eventually, we summarize a few combinations of DQT with other approaches such as numerical linked cluster expansions or projection operator techniques. In this way, we demonstrate the versatility of DQT.
Diterpenoid and phenolic contents of Sideritis hololeuca Boiss & Heldr. Apud Bentham with antioxidant and anticholinesterase activity
Authors: Carikci Sema , Goren Ahmet C. , Kilic Turgut 
Published: May 2020

Abstract
The objective of this study is to determine essential oil, diterpenoid and phenolic contents of Sideritis hololeuca along with their biological activities. Phytol was found to be the main component of the essential oil. Seven known kaurane diterpenoids, siderol (140 mg, 0.16%, w/w), 7-acetoxy sideroxol (15 mg, 0.02%, w/w), eubol (6 mg, 0.01%, w/w), eubotriol (5 mg, 0.03%, w/w), 7-epicandicandiol (3 mg, 0.02%, w/w), ent-7α-acetoxy-18-hydroxykaur-16-ene (5 mg, 0.01%, w/w) and linearol [by liquid chromatography-tandem mass spectrometry (LC-MS/MS)] were determined from the species. Moreover, vanillin (21 mg, 0.10%, w/w), which was not isolated from any Sideritis species earlier, was isolated from an acetone extract of S. hololeuca. Quantitative amounts of some phenolic compounds in n-hexane, dichloromethane, acetone, methanol extracts and infusion and decoction of the plants were also investigated by LC-MS/MS. Antioxidant capacity and acetylcholinesterase, butyrylcholinesterase inhibition effects of the species were evaluated. The extracts of methanol and infusion and decoction of species showed moderate butyrylcholinesterase inhibition activity. The highest inhibition was observed from the decoction of species. The Cu2+ reducing power of infusion was determined as 1.435 mmol TR g−1.
Catalytic Behavior of Molybdenum Sulfide for the Hydrogen Evolution Reaction as a Function of Crystallinity and Particle Size Using Carbon Multiwall Nanotubes as Substrates
Authors: Stellmach Diana , Xi Fanxing , Bloeck Ulrike , Bogdanoff Peter , Fiechter Sebastian 
Published: May 2020

Abstract
Molybdenum sulfide is of interest as a noble metal-free catalyst for the hydrogen evolution reaction (HER). In crystallized form, it shows a typical stacking of planar S–Mo–S layers whereas the catalytically active centers are situated on the edges of these entities characterized by non-saturated bonds of the molybdenum atoms. In this study, 2H-MoS2 is investigated as HER catalyst as a function of particle size using powder electrodes of different grain sizes and morphology. HER was also determined as a function of growth defects (bending of layers) and as a function of active sites employing MoS2 nanoparticles (NP). To study the influence of the substrate on the perfection of the transition metal disulfide, MoS2 nanosheets were deposited on multi-walled carbon nanotubes (MWCNTs) of different diameters. Highest activity was found for MoS2 nanosheets deposited on MWCNTs with a diameter smaller than 8 nm. At diameters larger than 10 nm, a wrapping of the nanotubes by partially bended stacks of S–Mo–S layers occurs, while at diameters smaller than 10 nm, individual MoS2 nanosheets of 3–5 S–Mo–S stacks of 3–4 nm in height and 10–20 nm in lateral extension surround the carbon nanotubes in form of hexagonal cylinders. The ratio of catalytically active non-van-der-Waals and hexagonal basal planes was determined electrochemically by electro-oxidation and correlated with HER activity.
Time-Resolved Measurements and Master Equation Modelling of the Unimolecular Decomposition of CH3OCH2
Authors: Eskola Arrke J. , Blitz Mark A. , Pilling Michael J. , Seakins Paul W. , Shannon Robin J. 
Published: May 2020

Abstract
The rate coefficient for the unimolecular decomposition of CH3OCH2, k
1, has been measured in time-resolved experiments by monitoring the HCHO product. CH3OCH2 was rapidly and cleanly generated by 248 nm excimer photolysis of oxalyl chloride, (ClCO)2, in an excess of CH3OCH3, and an excimer pumped dye laser tuned to 353.16 nm was used to probe HCHO via laser induced fluorescence. k
1(T,p) was measured over the ranges: 573–673 K and 0.1–4.3 × 1018 molecule cm−3 with a helium bath gas. In addition, some experiments were carried out with nitrogen as the bath gas. Ab initio calculations on CH3OCH2 decomposition were carried out and a transition-state for decomposition to CH3 and H2CO was identified. This information was used in a master equation rate calculation, using the MESMER code, where the zero-point-energy corrected barrier to reaction, ΔE
0,1, and the energy transfer parameters, ⟨ΔEdown⟩ × T
n, were the adjusted parameters to best fit the experimental data, with helium as the buffer gas. The data were combined with earlier measurements by Loucks and Laidler (Can J. Chem.
1967, 45, 2767), with dimethyl ether as the third body, reinterpreted using current literature for the rate coefficient for recombination of CH3OCH2. This analysis returned ΔE
0,1 = (112.3 ± 0.6) kJ mol−1, and leads to

k
1
∞

(
T
)

=

2.9
×

10
12

$k_{1}^{\infty}(T)=2.9\times{10^{12}}$

(T/300)2.5 exp(−106.8 kJ mol−1/RT). Using this model, limited experiments with nitrogen as the bath gas allowed N2 energy transfer parameters to be identified and then further MESMER simulations were carried out, where N2 was the buffer gas, to generate k
1(T,p) over a wide range of conditions: 300–1000 K and N2 = 1012–1025 molecule cm−3. The resulting k
1(T,p) has been parameterized using a Troe-expression, so that they can be readily be incorporated into combustion models. In addition, k
1(T,p) has been parametrized using PLOG for the buffer gases, He, CH3OCH3 and N2.
Modelle der konfessionellen Kooperation an Schulen und Hochschulen in Deutschland. Eine Bestandsaufnahme im Horizont einer gesamttheologisch verantworteten Religionslehrerinnen- und Religionslehrerbildung
Authors: Simojoki Henrik , Lindner Konstantin 
Published: May 2020

Zusammenfassung
Konfessionelle Kooperation im Religionsunterricht wird in Deutschland immer relevanter. In verschiedenen Bundesländern finden sich gegenwärtig unterschiedliche Umsetzungen dieser Kooperation, die von einer intensiven Zusammenarbeit evangelischer und katholischer Religionslehrkräfte bis zu einem Religionsunterricht in gemischt-konfessionellen Lerngruppen, den eine Lehrkraft allein verantwortet, reichen. Ein fachlich und didaktisch verantworteter konfessionell-kooperativer Religionsunterricht, der den unterschiedlichen Umsetzungsvarianten gerecht wird, bedarf entsprechend professionalisierter Religionslehrerinnen und Religionslehrer. Beide Aspekte – die unterschiedlichen Manifestationen konfessioneller Kooperation und die damit einhergehenden Erfordernisse an die Religionslehrerinnen- und Religionslehrerbildung – werden in vorliegendem Beitrag konturiert. Ein Überblick über existierende Formate einer kooperativ angelegten universitären Religionslehrkräftebildung und ein abschließendes Plädoyer für deren ökumenische Profilierung runden die Ausführungen ab.
Konfessionelle Kooperation in der Religionslehrerinnen- und -lehrerbildung – Plausibilität, Chancen und Grenzen in ökumenischer Perspektive
Authors: Hailer Martin 
Published: May 2020

Zusammenfassung
Konfessionell-kooperativer Religionsunterricht ist für die Systematische Theologie in ökumenischer Verantwortung genau dann verheißungsvoll, wenn er nicht als Sparmodell begriffen wird, sondern es zu echter Kooperation kommt, die in Vorgänge der wechselseitigen Anerkennung mündet. Der Beitrag umreißt die dafür nötigen Mindestbedingungen und weist auf religionspädagogische Konsequenzen hin.
Konfessionelle Kooperation in der Religionslehrerinnen- und -lehrerbildung – Möglichkeiten, Chancen und Grenzen an Studienstandorten ohne Kooperationspartner vor Ort
Authors: Schröder Bernd , Woppowa Jan 
Published: May 2020

Zusammenfassung
Der Beitrag sichtet und systematisiert institutionelle Voraussetzungen und mögliche Konstellationen einer konfessionell-kooperativen Ausrichtung der Religionslehrerinnen- und Religionslehrerbildung im Studium. Besonderes Augenmerk legt er auf Studienstandorte ohne lokalen Kooperationspartner. Für solche Studienstandorte werden verschiedene Möglichkeiten skizziert, trotz dieser widrigen Voraussetzungen konfessionell-kooperative Lehr-Lern-Settings zu implementieren. Ein Format zum konfessionell-kooperativen Lehren und Lernen im universitären Kontext, das die Autoren erprobt haben, wird exemplarisch vorgestellt.
Verteilung der Aufsichtskompetenzen in der Bankenunion
Authors: Tröger Tobias , Tönningsen Gerrit 
Published: May 2020

Zusammenfassung
Mit der Errichtung des Single Supervisory Mechanism (SSM) hat der europäische Gesetzbgeber die Aufsichtslandschaft der Eurozone umgewälzt und prudentielle Verantwortlichkeiten bei der Europäischen Zentralbank (EZB) konzentriert. Die fundamentale kompetenzielle Neuordnung wirft ebenso grundsätzliche wie praxisrelevante Fragen zur effizienten Verteilung aufsichtlicher Zuständigkeiten im europäischen Mehrebenensystem auf. Diesen geht der vorliegende Beitrag aus Anlass des L-Bank Verfahrens vor den Unionsgerichten nach. Ziel ist dabei nicht nur, das Urteil kritisch zu würdigen, sondern auch einen über den konkreten Einzelfall hinausweisenden, normativen Leitstern für die Kompetenzabgrenzung zwischen EZB und nationalen Aufsichtsbehörden zu entwickeln.