bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chronic gastroduodenal pathology in children with atopic dermatitis complicated by mycotic infection
Authors: Alekseeva I. G. , Malanicheva T. G. , Denisova S. N. , Nее A. , Kachalova O. V. 
Published: November 2020

Objective: To identify the features of chronic gastroduodenal pathology in children with atopic dermatitis (AD) complicated by secondary mycotic infection.Methods: The examination of mucous membrane micro-biocenosis of stomach and duodenum was performed in 64 children aged 3–16 years with diseases of gastrointestinal tract and AD complicated by fungal infection. 45 out of 64 patients, having been under medical supervision, had a combined damage of skin and gastrointestinal tract with Candida fungi. In-depth clinical and mycological study was performed represented by esophagogastroduodenoscopy with biopsy of intestine mucous membrane. The detection of circulating candida antigens in blood serum was conducted with method of amperometric enzyme biosensor. Helicobacter pylori were detected using urease test.Results: Children with AD combined with secondary mycotic infection had a damage of the upper parts of gastrointestinal tract and skin with Candida fungi in 70.3% of cases. Gastroduodenitis accounted for 66.7%; peptic ulcer disease was 33.3% in the structure of gastrodudenal pathology. Candida albicans fungi were plated in 80 % of cases; all children had a candida antigen in the blood serum.Conclusions: Children with AD, complicated by mycotic infection, and chronic gastrodudenal pathology should be examined for candidiasis of upper parts of gastrointestinal tract. If there is a candidiasis they should be prescribed with systemic antimycotics and dietary adjustment.
Prevalence of thromboembolic complications depending upon compliance and preventive care after endoprosthetics of large joints
Authors: Palshin G. A. , Pavlov S. S. , Markovchina M. Yu. , Komissarov A. N. , Markov P. V. , Vinokurov M. M. , Kostiv E. P. , Ustinova A. I. , Palshin V. G. 
Published: November 2020

Objective. The study objective is to assess the efficacy of preventive care for thromboembolic complications after endoprosthetics of large joints depending on patients’ compliance.Methods: Prospective clinical examination of 686 patients aged 50–70 years, who underwent the endoprosthetics of knee and hip joints. Preventive care for thrombosis and embolism was performed according to three regimens: 1) monotherapy with parenteral low molecular weight heparins, 2) therapy with low molecular weight heparins converted to indirect anticoagulants, 3) administration of oral anticoagulants.Results: 376 patients (54.8%) fully complied with the medical recommendations. The rest 310 patients (45.2%), non-compliant patients, ignored medical prescriptions: refusal to take anticoagulants, spontaneous replacement of anticoagulants with antiplatelet agents, not taking medications as prescribed. Among compliant patients, deep vein thrombosis of lower extremities was registered in 9 cases (2.4%); among non-compliant patients, it was registered in 13 cases (4.2%).Conclusions: Deep vein thrombosis of lower extremities was registered significantly more often in non-compliant patients. To increase the efficacy of the prevention care for thromboembolic complications after endoprosthetics of large joints, more attention should be paid to explanatory work, explaining to patients the nature and negative consequences of compliance violations.
Colorectal endoscopic submucosal dissection: The results of the first 200 procedures
Authors: Khalin K. D. , Agapov M. Yu. , Zvereva L. V. , Ogurchyenok N. E. , Ryzhkov E. F. , Barsukov A. S. , Stegniy A. S. 
Published: November 2020

Objective: The objective is to analyze the results of endoscopic submucosal dissections (ESDs) of large intestine tumors performed in one clinic.Methods: Data on 207 ESDs in large intestine for 2007–2019 were analyzed. The duration and speed of surgical operation, the number of en block resections and curable resections, and the level of complications and change of results within gain in experience were assessed. Results: According to locations, tumors are divided as follows: right-sided – 48, left-sided – 71, rectal – 88. The average speed of submucosal dissection was 13.5 mm2/min.; the average time taken for dissection of one square centimeter of a tumor was 12.5 min. The conversion to loop assistance was required in 35 cases, conversion to a laparoscopic resection – in two cases. According to criteria of endoscopic radical operations, 170 (82.1%) cases were considered curable. As experience of operations was gaining, despite the increase in number of tumors of right-sided location, the speed of ESDs was significantly increased, and the number of perforations and conversions to loop assistance was not changed.Conclusions: ESD is an effective method of large intestine tumor removal; however, during the training period, a professional should gain an experience in at least 100 operations.
Morphometric and topograpical analysis of retinal abnormalities in central serous chorioretinopathy
Authors: Maltsev D. S. , Malakhova E. Yu. , Kulikov A. N. , Kazak A. A. 
Published: November 2020

Objective: Quantitative morphometric and topographic analysis of specific changes of the retina in patients with the acute central serous chorioretinopathy (CSC) based on annotated tomograms.Methods: 39 patients with the acute CSC (44 eyes – 45 scans) were examined. A complex ophthalmological examination was carried out including 3D optical coherence tomography of maculae. The data was uploaded into CVAT. Three classes of pathological changes were differentiated: 1) retinal neuroepi‑ thelium detachment; 2) retinal pigment epithelium alteration; 3) percolation zones. The analysis of topographical localization of changes and their morphological relations were assessed with a programming language Python.Results: A moderate trend towards vertical asymmetry of the neuroepithelial detachment zone with an excess of cumulative distribution in the lower part of the macula was revealed. Retinal pigment epithelium alteration sites and percolation zones demonstrated a relative peak of representation in the upper nasal part of the macula. In 69.9% and 80% of cases, respectively, abnormalities of retinal pigment epithelium and percolation zones were localized within the limits of neuroepithelial detachment. Direct correlation between the area of neuroepithelial detachment and the area of percolation zones; the area of percolation zones and the area of retinal pigment epithelium alteration; the area of neuroepithelial detachment and the area of retinal pigment epithelium alteration.Conclusions: Percolation zones and abnormalities of retinal pigment epithelium demonstrate similar trends in topo‑ graphical localization and quantitative characteristics and are related to the area of neuroepithelial detachment in CSC. Thus, the number of retinal pigment epithelium abnormalities can serve as an indicator of disease severity.
Complications of various methods for implanting intraocular lenses in the surgical treatment of congenital cataract
Authors: Fediashev G. A. , Kasatkina I. S. , Makarevich E. S. 
Published: November 2020

Objective: Comparison of complications development rate in various methods for implanting intraocular lenses (IOLs) in the surgical treatment of congenital cataract.Methods: The results of surgical treatment of 16 children under 5 years old with bilat‑ eral congenital cataract were assessed. In each case, IOL was implanted according to the technique “optic capture” into one eye (the 1st group of study); the lens was implanted after capsulorrhexis and extraction of anterior segments of vitreous body into the second eye (the 2nd group of study).Results: Fibrinoplastic complications in the postoperative period were more often recorded in the 2nd group than in the 1st one (5 and 1 eyes, respectively). Epithelial proliferation in the 2nd group developed in 10, in the 1st group – in 5 eyes.Conclusions: In the surgical treatment of congenital cataract, implantation of IOLs according to the technique “optic capture” is an effective way of epithelial proliferation and opacity prevention reducing visual acuity in postoperative period. This method is safe regarding inflammatory fibrinoplastic reactions and allows maintaining normal anatomical position of the vitreoretinal structures of the growing eye.
Neurodegeneration of retina in patiens with type 2 diadetes mellitus
Authors: Ruchkin M. P. , Kuvshinova E. R. , Fedyashev G. A. , Markelova E. V. 
Published: November 2020

Objective: To detect early morphological and functional signs of neurodegeneration of the retina in patients with type 2 diabetes mellitus (DM) without signs of diabetic retinopathy (DR), to determine the presence and nature of the relationship between the studied parameters.Methods: The study included 30 patients with type 2 DM without DR (main group) and 30 healthy individuals (control group). Optical coherence tomography and microperimetry were performed.Results: In the main group, a significant decrease in the average photosensitivity of the retina and a decrease in its photosensitivity in the fovea and in the upper, lower, and temporal quadrants of parafovea were revealed. A significant difference between the groups was also recorded in the thickness of the inner layers of the retina in the temporal quadrant of parafovea. There was also a significant difference in the volume of focal loss of retinal ganglion cells.Conclusions: Neurodegenerative and related functional changes in the retina were revealed in patients with type 2 DM without signs of DR. Retinal neurodegeneration is one of the reasons for the deterioration of visual function in patients with DM and can aggravate the prognosis of the disease. Optical coherence tomography and microperimetry can be used for early diagnosis and monitoring of this process.
Dispersed biocomposite based on wollastonite/hydroxyapatite: Osteoplastic potential in terms of radiology
Authors: Apanasevich V. I. , Papynov E. K. , Afonin I. S. , Evdokimov I. O. , Shichalin O. O. , Stepanyugina A. K. , Pankratov N. R. , Korshunova O. V. , Agafonova I. G. , Zinoviev S. V. , Geltser B. I. 
Published: November 2020

Objective: assessment of the bone tissue regeneration of alveolar ridge during implantation of biocomposite based on wollastonite/hydroxyapatite (HA) in the experiment.Methods: Four female rabbits were performed the extraction of lower left incisors under the general and local anesthesia followed by the augmentation with biocomposite. The results were assessed with cone beam computed tomography.Results: On the first day, the average density of bone structure of the alveolar socket was 37 HU; on the 60th day, it reached 1090 HU. The contour of the alveolar socket was not already visible on the 35th day. There were no signs of the osteolysis.Conclusions: The experiment result confirms the the participation of a CaSiO3/HA biocomposite in bone tissue regeneration, as evidenced by the dynamics of the increase in bone volume in the alveoli of the removed teeth of the lower jaw of experimental animals.
The effectiveness of targeted therapy with bevacizumab combined with chemotherapy for metastatic colorectal cancer
Authors: Ovodova A. V. , Petukhova Yu. Yu. , Eliseeva E. V. , Perelomova O. V. 
Published: November 2020

Objective: To estimate the effectiveness of the target therapy with bevacizumab combined with chemotherapy for metastatic colorectal cancer.Methods: Life expectancy of 208 patients having 3rd and 4th stages was retrospectively analyzed. They received different kinds of treatment: FOLFOX, canecitabin with FOLFOX combined with bevacizumab.Results: Average life expectancy of the patients having 3rd stage of colorectal cancer is 11.4 months of those who applied FOLFOX scheme, and 14.4 months taking “FOLFOX+bevacizumab” scheme. Of those patients having the 4th stage of cancer this combination of chemotherapy and target medicine resulted in an increase in life expectancy for 3.7 months.Conclusions: Inclusion of bevacizumab in treatment plan of the patients having 3rd and 4th stages of colorectal cancer improves life expectancy indexes of the patients.
Practical application of the cell block technique for the diagnostics of the tumors of the pancreas and of other localizations
Authors: Kotsyrbiy E. A. , Tychonov Y. N. , Nazarova I. V. , Reznichek I. O. , Tumanina A. N. , Gorelik M. Z. 
Published: November 2020

Liquid-based material and traditional pap smears got during fine-needle biopsies of different tumors were analyzed. Cell-cycle blocks and monolayer pills were made from liquid-based material depending on the amount of cell structures. Original method using donor thrombocyte mass was implemented to create cell-cycle blocks, especially to condense and consolidate the sediment after centrifugation. After taking pancreas punctures different medical institutions in Vladivostok managed to form cell-cycle blocks in 71 cases from 2017 to 2019. In 9 cases (12.7%) the material was found to be diagnostically noninformative, in 15 cases (21.2%) – sufficient for morphological research, but inappropriate for immunohistochemistry. In 47 cases (66.1%) 206 immunohistochemical tests were made using 34 types of biomarkers.
The features of the primary dynamics disability in Primorskiy Region adult population level from 2017 to 2019
Authors: Derbenev D. A. , Drozdov C. V. , Derbeneva I. V. 
Published: November 2020

Objective: Comparative analysis of the dynamics and causes of the primary disablement of the population of Primorskiy region.Methods: Statistical indicators of the primary disablement were compared using statistical and analytical methods.Results: Statistically important differences of the levels of primary disablement not only in general, but also according to nosological forms were identified. They pointed out the high level of the invalidization of the population of Primorskiy region among the patients having tuberculosis, disease caused by HIV, diseases of the oste-muscular system and of the connective tissue, the effects of injuries, poisoning and other impacts of external causes. The increase in the level of primary disablement was defined including consequently to the disease caused by HIV, malignant tumors, diseases of the ear and the mastoid and genitourinary diseases and the decrease was defined due to tuberculosis and occupational pathology.Conclusions: The causes of the differences in the levels of primary disablement among the adult population in Primorskiy region and in Russian Federation in general and in certain classifications and units of diseases require futher studying based on interdepartmental interaction of the specialists.
Adoption of Knowledge Management System: A Study on How IGracias Should be Adopted for Telkom Campus
Authors: Rahmawati Dewi , Istyanto Noerma Pudji , Nasrul Muhammad 
Published: November 2020

ABSTRAK
IGraciass merupakan sistem informasi manajemen akademik dan nonakademik terintegrasi dari Yayasan Pendidikan Telkom (YPT). Berdasarkan visi dan misi, strategi dan tagline dari Yayasan Pendidikan Telkom adalah “The Leader of ICT Education Provider” serta semangat transformasi digital untuk Indonesia, maka I-Graciass wajib di adopsi dan diimplementasikan di seluruh lembaga pendidikan tinggi (lemdikti) yang ada di bawah nauangan YPT tersebut. Namun, fakta di lapangan proses adopsi dan implementasi I-Graciass di masing-masing lembaga pendidikan tinggi tersebut bukan perihal yang mudah. Fitur yang banyak, kemudahan menggunakan teknologi serta Sistem Interface yang diperlukan untuk mengakses sistem merupakan faktor penting dalam keberhasilan sistem. Untuk itu, penelitian ini dilakukan dengan tujuan agar memudahkan proses adopsi IGraciass di seluruh lembaga pendidikan tinggi Yayasan Pendidikan Telkom (YPT) sesuai dengan kebutuhan masing-masing dari lembaga pendidikan dibawah naungan YPT. Penelitian ini dilaksanakan dengan menggunakan metode mixing method baik secara kualitatif dan kuantitatif, kemudian peneliti juga menyusun instrumen penelitian kualitatif untuk melakukan survey terhadap pihak pengguna untuk mengetahui saluran (channel) yang efektif dalam melakukan proses transfer knowledge. Hasil penelitian menunjukkan bahwa untuk meminimalkan risiko kegagalan dalam mengadopsi sistem knowledge management system, perusahaan perlu memilih sistem berdasarkan persyaratan fungsional, non-fungsional dan transisi untuk sistem, serta kekuatan dan kapasitas organisasi.
Instrumen Kemampuan Berpikir Kreatif Matematika untuk Siswa Kelas IV Sekolah Dasar
Authors: Astuti Astuti , Waluya Stevanus Budi , Asikin Mohammad Budi 
Published: November 2020

Matematika perlu diajarkan karena membentuk dan mengembangkan kemampuan berpikir kreatif, kritis, logis, dan sistematis. Berpikir kreatif diperlukan siswa dalam menyelesaikan masalah yang dihadapi dan yang akan dihadapi suatu saat nanti. Berpikir kreatif memiliki empat indikator, meliputi fluency, flexibility, originality, dan elaboration. Penelitian ini bertujuan untuk mengetahui hasil uji coba soal kemampuan berpikir kreatif siswa sebuah SD di kota Ungaran. Pendekatan penelitian yang digunakan adalah kuantitatif dengan metode deskriptif analisis. Instrumen yang dipakai yakni tes kemampuan berpikir kreatif. Terdiri dari soal yang memuat indikator kemampuan berpikir kreatif. Pengambilan data dilakukan pada siswa kelas IV dengan sample berjumlah 35 siswa. Berdasarkan hasil uji coba soal bahwa soal tes kemampuan berpikir kreatif semua valid; reliable dengan tingkat kesukaran sulit, sedang, dan mudah; serta daya pembeda sangat baik, baik, buruk, dan sangat buruk. Dengan demikian, soal tes kemampuan berpikir kreatif yang telah disusun dapat digunakan untuk penelitian.
PENERAPAN DATA MINING UNTUK PREDIKSI PENJUALAN PRODUK TRIPLEK PADA PT PUNCAK MENARA HIJAU MAS
Authors: Rustam Rustam , Rahmatullah Sidik , Supriyato Supriyato , Wahyuni Sri 
Published: November 2020

Permasalahan yang terjadi pada handphone memerlukan suatu perangkat lunak yang berupa aplikasi program yang sesuai dengan permasalahan yang terjadi didunia usaha. Metode yang digunakan dalam penelitian ini adalah forward chaining dan certainty factor. Dari penelitian ini akan menghasilkan sebuah sistem pakar yang dibangun menggunakan bahasa pemrograman PHP dan database MySQL. Setelah dilakukan implementasi dan pengujian sistem pakar yang dibuat bertujuan untuk menggantikan seorang pakar dalam mendiagnosa kerusakan handphone.
Pengembangan Model Pembelajaran Problem Based Learning pada Mata Kuliah Kewirausahaan
Authors: Puspa Rani , Panudju Andreas Tri 
Published: November 2020

Mahasiswa adalah ujung tombak keberhasilan pembangunan suatu negara, oleh karenanya output dan outcome suatu institusi perguruan tinggi mendapat perhatian yang cukup serius. Lulusan saat ini dituntut untuk mampu dalam hal menciptakan kreativitas dan inovatif dalam menyelesaikan suatu permasalahan di dunia nyata sekaligus paham terkait perkembangan teknologi. Paradigma tersebut membuat terjadinya pergeseran paradigma proses pembelajaran yaitu dari metode konvensional menjadi metode Problem Based Learning. Salah satu mata kuliah yang berkaitan dengan kreativitas dan inovasi adalah mata kuliah Kewirausahaan dan kegiatan pengabdian masyarakat ini mencoba menerapkan metode pembelajaran Problem Based Learning pada mata kuliah ini. Metode yang digunakan adalah metode kegiatan pengabdian masyarakat research & development (R&D) dan diperoleh hasil bahwa metode Problem Based Learning secara signifikan memberikan hasil yang positif baik ditinjau dari pelaksanaan proses pembelajaran maupun hasil evaluasi mahasiswa yaitu peningkatan nilai yang cukup signifikan antara pretest dan posttest.
Revitalisasi Bangunan Masjid Al Firdaus Bojong Pondok Terong, Cipayung, Depok
Authors: Masri Zainal Arifin , Alam Bambang Perkasa 
Published: November 2020

Kegiatan pengabdian kepada masyarakat (abdimas) ini dilakukan di Kelurahan Bojong Pondok Terong, Kecamatan Cipayung, Kota Depok. Abdimas ini merupakan program kemitraan dengan mitra kerja sama Dewan Kemakmuran Masjid (DKM) Al Firdaus. Masjid Al Firdaus didirikan sekitar tahun 1970-an saat ini merupakan bangunan tua yang dikhawatirkan dapat membahayakan keselamatan jamaah/masyarakat yang sedang melaksanakan ibadah. Di samping itu kapasitas masjid tidak lagi mencukupi untuk menampung jamaah salat Jumat. Oleh karena itu DKM Al Firdaus bermaksud merenovasi bangunan masjid secara total/menyeluruh dengan prinsip dari jamaah, oleh jamaah dan untuk jamaah. DKM Al Firdaus menghadapi kendala di mana tidak ada jamaah masjid yang merupakan tenaga ahli dibidang teknik sipil dan arsitek. Tim dosen abdimas Universitas Indraprasta (Unindra) PGRI menawarkan kepada DKM Al Firdaus kerja sama kemitraan yang saling menguntungkan untuk melaksanakan renovasi masjid Al Firdaus. DKM Al Firdaus menyelesaikan persoalan-persoalan perijinan, kemungkinan adanya gugatan dari ahli waris yang telah mewakafkan tanahnya, adanya keberatan warga/jamaah terhadap renovasi masjid dan lain sebagainya. Sedangkan tim dosen abdimas Unindra PGRI menyiapkan tenaga ahli yang akan mengerjakan tugas-tugas antara lain praperencanaan meliputi meninjau lokasi masjid, luas tanah, bentuk tanah dan struktur tanah, perencanaan berupa desain arsitektur masjid dan rencana anggaran belanja (RAB) dan ikut mengawasi pelaksaan pembangunan dari segi teknis bangunan.
RISK FACTORS OF ECONOMIC SECURITY IN THE FOREIGN TRADE SPHERE OF SAMARA REGION IN THE CONDITIONS OF THE PANDEMIC
Authors: Хмелева Галина Анатольевна 
Published: November 2020

В статье проведен анализ объемно-структурных параметров экспортно-импортных товаропотоков Самарской области, определены риск внешнеэкономической безопасности в условиях пандемии.
The article analyzes the volumetric-structural parameters of the export-import flows of the Samara region, identifies the risk of external economic security in a pandemic.
THE RELATIONSHIP BETWEEN MENTAL AND PHYSICAL ACTIVITY ON PERSONAL DEVELOPMENT
Authors: Немцева Елена Владимировна , Кононенко Оксана Александровна , Клепиков Игорь Георгиевич 
Published: November 2020

В статье проведён анализ связи между физической активностью и умственной деятельностью человека. Связь заключается в том, что физическая активность осуществляет благоприятные условия для мозговой деятельности. Был изучен процесс утомления организма в ходе физических нагрузок. А также рассмотрены варианты его восстановления.
The article analyzes the relationship between physical activity and mental activity of a person. The connection is that physical activity provides favorable conditions for brain activity. The process of body fatigue during physical exertion was studied. And also considered options for its recovery.
SUTURE SIZE OPTIMIZATION IN THE MODEL OF FOCAL ISCHEMIA IN RATS
Authors: Кудабаева Марина Станиславовна , Акулов Андрей Евгеньевич , Пищелко Анна Олеговна , Светлик Михаил Васильевич , Ходанович Марина Юрьевна 
Published: November 2020

На модели окклюзии срединой церебральной артерии (MCAO) у крыс исследовано влияние параметров монофиламента, используемого для проведения операции, на объем ишемического поражения мозга. Установлена оптимальная длина наконечника филамента, обеспечивающая такой объем ишемического поражения, который позволяет обеспечить хорошую выживаемость животных в сочетании с другими инвазивными процедурами в хроническом эксперименте.
In middle cerebral artery occlusion model (MCAO) in rats surgical suture characteristics were analyzed as parameters that can effect on ischemic lesion size. Optimal suture lenght was assigned for inducing ischemic lesion size that facilitates animal survival in long-term experiment, if MCAO and other invasive procedures are combined.