bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating The Implementation of The SWITCH® School Wellness Intervention Through Mixed Methods
Authors: McLoughlin Gabriella M. , Candal Priscila , Vazou Spyridoula , Lee Joey A. , Dzewaltowski David A. , Rosenkranz Richard R. , Lanningham-Foster Lorraine , Gentile Douglas A. , Liechty Laura , Chen Senlin , Welk Gregory J. 
Published: July 2020

Abstract
Background: School wellness programming is important for promoting academic achievement and healthy lifestyles in youth; however, research is needed on methods that can help schools implement and sustain programs on their own. The purpose of this study was to investigate factors within and outside the school environment that impacted school capacity for implementation and potential sustainability of wellness programming. Methods: As part of the School Wellness Integration Targeting Child Health (SWITCH®) intervention, elementary school wellness teams (N=30) were guided through a capacity-building process focused on promoting the adoption of healthy lifestyle behaviors in students. Data on implementation were collected through three standardized surveys and interviews (pre-mid-post) and a post-implementation interview. Indicators of organizational capacity were assessed using the School Wellness Readiness Assessment (SWRA). Paired t-tests were run to assess changes in implementation (classroom, physical education, lunchroom settings), capacity, and stakeholder engagement over time. One-way analysis of variance (ANOVA) tests were run to examine how implementation of best practices (low, moderate, high) explained differences in capacity gains. Qualitative data were analyzed through inductive and deductive analysis, following the Consolidated Framework for Implementation Research (CFIR). Results: Paired t-tests showed non-significant increases in school and setting-specific capacity and implementation of SWITCH best practices over time, in addition to a consistent level of engagement from key stakeholders. ANOVA analyses revealed positive, non-significant variances between implementation group and gains in school capacity (F[2,24]=1.63; p=.21), class capacity (F[2,24]=0.20 p=.82), lunchroom capacity (F[2,24]=0.29; p=.78), and physical education (F[2,24]=1.45; p=.25). Qualitative data demonstrated factors within the outer setting (i.e., engaging community partners) that facilitated programming. Inner-setting factors (i.e., relationships with administration and staff) significantly affected implementation. Implementation process construct themes (e.g., planning, adaptation of resources to meet school capacity/needs, and engaging students as leaders) were cited as key facilitators. Schools discussed factors impacting sustainability, such school culture and knowledge of school wellness policy. Conclusions: Findings suggest a modest but important impact of implementation on capacity change which is the primary goal of SWITCH. The results document the importance of allowing schools to adapt programming to meet their local needs.
Conception and evaluation methodology of water resources carrying capacity based on three-level analysis
Authors: Lin Pengfei , You Jinjun , Wang Lin , Jia Ling , Gan Hong , Fu Yicheng 
Published: July 2020

AbstractIn supply-oriented water development, water is a rigid constraint on sustainable development in many parts of the world, especially in arid and semi-arid areas. The water resources carrying capacity (WRCC) concept represents the maximum socio-economic scale that can be supported by water exploitation without causing an irreversible impact on the ecosystem. In this paper, three-level framework is put forward to illustrate and quantitatively evaluate the WRCC. The first level is the principal body, which focuses on the study of water resources systems. The second level is the carried object, including the socio-economic system, water ecological system, and environment system. The third level is the coupling of the principal body and carried object to calculate the WRCC. This three-level WRCC model was applied to the load conditions of the Shiyang River Basin (SRB). The results show that the SRB is overloaded, and only 1.99 million people can be carried at the modern carrying level. The WRCC could be increased by optimizing industrial structures and improving water efficiency. This method provides a tool to help policymakers develop sustainable approaches to environmental management and planning.
Study on degradation of diesel pollutants in seawater by composite photocatalyst MnO2/ZrO2
Authors: Tian Siyao , Yu Xiaocai , Yin Danni , Wang Liping , Liao Jiaqi , Zhu Wanting 
Published: July 2020

Abstract
In this paper, the effectiveness of the composite photocatalyst was studied by using manganese dioxide (MnO2)/zirconium dioxide (ZrO2) to degrade diesel pollutants in seawater under visible light.The MnO2/ZrO2 photocatalyst was prepared by co-precipitation and characterized by scanning electron microscopy, X-ray powder diffraction, energy-dispersive spectroscopy and UV-Vis diffuse reflectance spectroscopy analysis. This is the first report on a comprehensive analytical study on the effect of various physio-chemical parameters on diesel degradation using the synthesized MnO2/ZrO2 photocatalysts. The effects of doping ratio of MnO2/ZrO2, dosage, initial diesel concentration, calcination temperature, concentration of H2O2 solutions and illumination time on the diesel degradation were investigated. The degradation of diesel pollution in seawater was optimized by orthogonal experiment. According to the results, the prepared samples were monoclinic form and the MnO2 was successfully doped into the bulk ZrO2. The absorption edge of the MnO2/ZrO2 photocatalysts exhibited red shift, and this red shifts imply enhanced photon absorption under visible light compared with the pure ZrO2. The results showed that under optimum reaction conditions, the degradation rate can reach 92.92%. The result of this study will enable ZrO2 to make more effective use of sunlight and improve the actual value of photocatalytic technology in the field of contaminant treatment.
AVALIAÇÃO DO DESEMPENHO DOS CENTROS DE ESPECIALIDADES ODONTOLÓGICAS DO SERIDÓ POTIGUAR NO PERÍODO DE 2012 A 2017
Authors: Garcia Silva Correia Thereza Raquel , Mendes da Veiga Pessoa Daniela 
Published: July 2020

A política nacional de saúde bucal foi elaborada tendo como um dos objetivos a ampliação e qualificação da atenção especializada com a criação dos Centros de Especialidades Odontológicas (CEO). Para isso ações de monitoramento de produção se fazem necessárias na busca de uma maior efetividade das ações produzidas. O trabalho teve como objetivo avaliar o desempenho dos dois CEO instalados nos municípios pólos de atenção à saúde na região Seridó Potiguar, a partir do cumprimento das metas de procedimentos clínicos propostas pela Portaria GM Nº 1.464/2011. O estudo é do tipo quantitativo, descritivo e exploratório. Para a análise de desempenho dos serviços odontológicos especializados, foi calculado o índice Cumprimento Global de Metas (CGM) para os procedimentos em endodontia, periodontia e cirurgia oral menor, extraídos do Sistema de Informação Ambulatorial do SUS (SIA-SUS). Ambos os municípios pesquisados apresentaram desempenho insatisfatório no período avaliado, variando de ruim à regular, onde possivelmente, fatores como cobertura populacional de equipes de saúde bucal na atenção básica e falhas na referência e contra-referência para a atenção secundária apontam uma desorganização dos serviços nos diferentes níveis de atenção, causando a falta da integralidade do cuidado.

Palavras-chave: Saúde Bucal. Assistência Odontológica Integral. Avaliação de Serviços de Saúde.
Electroanalytical Analysis of Guaifenesin on Poly(Acridine Orange) Modified Glassy Carbon Electrode and its Determination in Pharmaceuticals and Serum Samples
Authors: Işık Hasan , Öztürk Gökçe , Ağın Fatma , Kul Dilek 
Published: July 2020

Background:
Electroanalytical methods are very functional to detect drugs in
pharmaceuticals (tablets, syrups, suppositories, creams, and ointments) and biological samples.

Objective:
This study is aimed to make selective, sensitive, simple, fast, and low cost
electrochemical analysis of expectorant drug guaifenesin in pharmaceuticals and serum samples.

Methods:
Differential pulse adsorptive stripping voltammetric method for determination of
guaifenesin on a poly(acridine orange) modified glassy carbon electrode has been developed.
Glassy carbon electrode was modified with electropolymerization of the acridine orange monomer
for the sensitive determination of guaifenesin. Guaifenesin provided highly reproducible and welldefined
irreversible oxidation peaks at +1.125 V and +1.128 V (vs. Ag/AgCl) in the selected
supporting electrolyte and human serum samples, respectively.

Results:
Under optimized conditions, linear response of peak current on the concentration of
guaifenesin has been obtained in the ranges of 2.00×10-7 to 1.00×10-4 M in Britton Robinson buffer
solution at pH 7.0 and 4.00×10-7 to 1.00×10-4 M in serum samples. The precision of the method
was detected by intraday and inter-day repeatability studies in the supporting electrolyte and serum
samples media.

Conclusion:
The analytical applicability of the proposed method exhibited satisfying
determination results for guaifenesin from pharmaceutical dosage forms (syrup) and human serum
samples without any pre-separation procedures.
HPTLC Method for the Determination of Metformin Hydrochloride, Saxagliptin Hydrochloride, and Dapagliflozin in Pharmaceuticals
Authors: Abdelrahman Afnan E. , Maher Hadir M. , Alzoman Nourah Z. 
Published: July 2020

Background:
Type 2 diabetes mellitus is an expanding health problem. Binary antidiabetic
combinations of Metformin Hydrochloride (MET) with either Saxagliptin Hydrochloride (SAX),
or Dapagliflozin (DAP) are widely used. Review of the literature revealed that no single HPTLC
method has been reported for the simultaneous determination of MET, SAX, and DAP allowing the
determination of binary mixtures of any two of the three cited drugs in their tablets using the same
experimental conditions, an important advantage for quality control. The advantages of HPTLC
method relies on the simultaneous analysis of a large number of samples in a shorter analysis time,
less solvent consumption, and less expenses, compared with HPLC.

Objective:
The objective of the proposed method is to develop and validate a single and simple
HPTLC densitometric method for the simultaneous determination of MET, SAX, and DAP.

Methods:
Separation was performed using aluminum HPTLC sheets coated with silica gel 60 F254
with a mobile phase consisting of a mixture of acetonitrile: 1% w/v ammonium acetate in methanol
(9: 1, v/v). Scanning was performed at 210 nm.

Results and Discussion:
Linearity of the method was assessed in the concentration range of 0.25-10
μg/band for SAX and DAP and 0.25-25 μg/band for MET. The method was fully validated as per the
ICH guidelines. The proposed method provided error and deviation values of less than 2% assessing
good accuracy and precision.

Conclusion:
The method was successfully applied to the analysis of pharmaceutical tablets of
MET/SAX, MET/DAP, and SAX/DAP with high specificity.
Recent Developments in CE-MS Based Metabolomics
Authors: Çelebier Mustafa , Nenni Merve 
Published: July 2020

Background:
Metabolomics has gained importance in clinical applications over the last
decade. Metabolomics studies are significant because the systemic metabolome is directly affected
by disease conditions. Metabolome-based biomarkers are actively being developed for early diagnosis
and to indicate the stage of specific diseases. Additionally, understanding the effect of an intervention
on a living organism at the molecular level is a crucial strategy for understanding novel or
unexpected biological processes.

Results:
The simultaneous improvements in advanced analytical techniques, sample preparation
techniques, computer technology, and databank contents have enabled more valuable scientific information
to be gained from metabolomics than ever before. With over 15,000 known endogenous
metabolites, there is no single analytical technique capable of analyzing the whole metabolome.
However, capillary electrophoresis-mass spectrometry (CE-MS) is a unique technique used to analyze
an important portion of metabolites not accessible by liquid chromatography or gas chromatography
techniques. The analytical capability of CE, combined with recent sample preparation techniques
focused on extracting polar-ionic compounds, makes CE-MS a perfect technique for metabolomic
studies.

Conclusion:
Here, previous reviews of CE-MS based metabolomics are evaluated to highlight recent
improvements in this technique. Specifically, we review papers from the last two years (2018 and
2019) on CE-MS based metabolomics. The current situation and the challenges faced by metabolomic
studies are discussed to reveal the high potential of CE-MS.
Specifics of Translating Osteopathic Terminology from English into Latvian
Authors: Kaļiņina Irina 
Published: July 2020

The present article explores the complex issue of translation in the field of biodynamic osteopathic terminology. Due to the status of this discipline in Latvia, terms in the source language (English) still need to be transposed into Latvian, implementing the process of secondary term creation. The research examines community-generated translation practices and provides an overview of the resulting situation. The principles of terminological work are based on the communicative and frame-based theories of terminology, with the grounding principles of the General Theory of Terminology (GTT). The methodology includes qualitative and quantitative analysis of term translations obtained from 7 respondents, based on a corpus of 229 terms extracted from course books and didactic CDs in the field of biodynamics in osteopathy. The resulting data on user-generated translation practices can serve as a basis for further exploration of the given terminology in a more prescriptive key.
Internationalizing Secondary Education in Poland Through English as a Medium of Instruction
Authors: Król Anna Maria , Romanowski Piotr 
Published: July 2020

Since English as a lingua franca is extending into virtually all domains of public life, non-Anglophone countries move away from the approach of English being taught as a foreign language (EFL) to the practice of English being a medium of instruction for content subjects. The methodology is increasingly implemented at all educational levels from primary to tertiary education. Yet few empirical studies have been undertaken into how the programmes are run. Thus, the article presents the findings of a research project, which attempted to provide a broad picture of this phenomenon in the Polish context. The article explores the two most recognized bilingual programmes in the European Union, Content and Language Integrated Learning (CLIL) and English Medium Instruction (EMI), both being thoroughly investigated in the paper. The article attempts to shed light on the teaching approaches applied in EMI classes. In addition, it discusses the extent to which the English language is used in such classes (partial or exclusive). Further, it focuses on the implications L1 interference has for the L2 learning process taking place in the classroom. Last but not least, the study gives a brief account of students’ and teachers’ perspectives on and attitudes towards EMI. Regarding the methodology, the triangulation of methods was adopted including questionnaires, interviews and observations.
Meningkatkan Kemampuan Menulis Cerita Fantasi dengan Penggunaan Video Anak “Malin Kundang”
Authors: Indriani Made Sri 
Published: July 2020

Penelitian Tindakan Kelas (PTK) ini bertujuan (1) mengetahui langkah-langkah meningkatkan kemampuan menulis cerita fantasi dengan menggunakan video anak “Malin Kundang” pada siswa kelas VII 3 SMP Laboratorium Undiksha, (2) mengetahui peningkatan kemampuan siswa menulis cerita fantasi melalui video anak “Malin Kundang” pada siswa kelas VII 3 SMP Laboratorium Undiksha, dan (3) mengetahui respons siswa terhadap penggunaan video anak “Malin Kundang” dalam meningkatkan keterampilan menulis cerita fantasi di kelas VII 3 SMP Laboratorium Undiksha. Subjek dalam penelitian ini adalah siswa kelas VII 3 SMP Laboratorium Undiksha. Objek penelitian ini adalah langkah-langkah meningkatkan kemampuan menulis cerita fantasi dengan menggunakan video anak “Malin Kundang” pada siswa kelas VII 3 SMP Laboratorium Undiksha, peningkatan kemampuan siswa menulis cerita fantasi melalui video anak “Malin Kundang” pada siswa kelas VII 3 SMP Laboratorium Undiksha, dan respons siswa terhadap penggunaan video anak “Malin Kundang” dalam meningkatkan keterampilan menulis cerita fantasi di kelas VII 3 SMP Laboratorium Undiksha. Metode pengumpulan data yang digunakan dalam penelitian ini adalah observasi, tes, kuesioner dan wawancara. Data yang didapatkan dianalisis dengan teknik deskriptif-kualitatif dan deskriptif-kuantitatif. Hasil penelitian ini menunjukkan bahwa, (1) berdasarkan hasil observasi yang dilakukan, dapat dikatakan bahwa langkah-langkah pelaksanaan pembelajaran yang dilakukan guru sudah tergolong baik/bagus. Hal ini dapat dilihat dari penilaian yang diberikan peneliti atau observer saat mengamati guru mengajar. (2) penggunaan video anak "Malin Kundang: dapat meningkatkan kemampuan menulis cerita fantasi siswa. Hal ini dapat dilihat dalam perbandingan skor rata-rata klasikal, yakni pada pratindakan skor rata-rata klasikal 68.14 (cukup), siklus I memperoleh skor rata-rata klasikal 76,66 (baik), sedangkan pada siklus II nilai rata-rata klasikal siswa menjadi 82,95 (baik); (3) siswa memberikan respons sangat positif dan positif terhadap penggunaan video anak "Malin Kundang" dalam pembelajaran menulis cerita fantasi. Dari hasil yang telah dicapai, bahwa penggunaan video anak "Malin Kundang" perlu dipertimbangkan sebagai upaya untuk mengoptimalkan proses dan hasil belajar bahasa dan sastra Indonesia.
Penerapan Prinsip Hukum Perjanjian dalam Kontrak Kerjasama Pengelolaan Barang Milik Daerah
Authors: Utami Pangestika Rizki 
Published: July 2020

The purpose of this study is to analyze the legal construction of the Regional Property Management Agreement. Regional property in the form of land and/or buildings and other than land and/or buildings that have been handed over by the user to the manager can be utilized optimally in order not to burden the Regional Budget and Revenues particularly maintenance costs. This article are reviewing several types of agreements by analyzing the application of the legal agreement principles in the cooperation contract in the management of property in Regional Government of Banyumas Regency. The principles of treaty law which is a concept of civil law applied in the concept of state administration law are interesting because the agreement is in the regulation of private law and public law. Government Contract is a routine legal act of government, to ensure legal certainty for the parties involved required legislation that specifically regulates commercial contracts by the government regarding procedures and authority limits.
Multiparameter flow cytometry for assessment of minimal residual disease in patients with myelodysplastic syndromes treated with allogeneic stem cell transplantation
Authors: Wiśniewska-Piąty Katarzyna , Dziaczkowska-Suszek Joanna , Wieczorkiewicz-Kabut Agata , Chromik Karolina , Koclęga Anna , Woźniczka Krzysztof , Grygoruk-Wiśniowska Iwona , Kata Dariusz , Zielińska Patrycja , Helbig Grzegorz 
Published: July 2020

AbstractBackgroundMyelodysplastic syndromes (MDSs) are a heterogeneous group of clonal myeloid neoplasms. Allogeneic stem cell transplantation (allo-SCT) remains the curative method for MDS treatment. Little is known about the monitoring of minimal residual disease (MRD) in patients with MDS after allo-SCT.AimWe aimed to evaluate the significance of leukemia-associated immunophenotypes (LAIPs) identified in acute myeloid leukemia (AML) for MRD monitoring in patients with MDS after allo-SCT.Material and methodsSeven males and 4 females with a median age of 55 years were included. The diagnosis of MDS was established according to 2016 World Health Organization (WHO) criteria. The significance of eight LAIPs in bone marrow samples using multiparameter flow cytometry (MFC) was evaluated for MRD.ResultsEight patients were positive for several LAIPs before allo-SCT. The identified LAIPs included the presence of aberrant lymphoid antigens on myeloblasts and lack of CD33 expression on myeloblasts. All studied MDS patients were negative for LAIPs at Day +30 after the procedure. This was followed by full-donor chimerism in all cases. The Ogata score after allo-SCT decreased in all patients in whom it was indicative for MDS before allo-SCT.ConclusionsMFC could be useful in monitoring MRD in MDS patients after allo-SCT. Further studies in this field are needed.
In vitro and in vivo effect of 3-Para-fluorobenzoyl-propionic acid on rat liver mitochondrial permeability transition pore opening and lipid peroxidation
Authors: Olowofolahan Adeola O. , Bolarin Omosola L. , Olorunsogo Olufunso O. 
Published: July 2020

Abstract
The opening of mitochondrial permeability transition (mPT) pore is a well recognized important event in the execution of mitochondrial-mediated apoptosis. Some bioactive compounds induce apoptosis in tumour cells via the induction of mPT pore opening. This study therefore investigated the effect of 3-Para-fluorobenzoyl-propionic acid (3PFBPA), a metabolite of haloperidol on mPT pore, mitochondrial ATPase activity (mATPase), mitochondrial lipid peroxidation (mLPO) and cytochrome c release (CCR). Thirty-two male Wistar rats, were acclimatized for 14 days in clean cages. After 30 days of treatment, they were sacrificed and the liver mitochondria isolated using differential centrifugation. The mPT pore, mATPase, mLPO and CCR were determined by standard methods using a spectrophotometer. The mPT pore opening was induced by 3PFBPA by 1.4, 3.6, 5.6, 6.6 and 7.4 folds, when compared with the control. Also, there was release of cytochrome c and enhancement of mATPase activity by 3PFBPA. The results also show that 3PFBPA reduced lipid peroxidation. However, oral administration of 3PFBPA at 50, 100 and 200 mg/kg did not have any effect on mPT pore opening and mATPase activity when compared with the control but there was inhibition of mLPO. These findings suggested the pharmacological potential of 3PFBPA against the pathological processes related to insufficient apoptosis (based on the in vitro data) and oxidative stress due to its anti-lipidperoxidative effect.