bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental study and numerical analysis on seismic performance of steel beam‐column damping joint in Chinese traditional style buildings
Authors: Sui Yan , He Zhenhua , Xue Jianyang , Wu Zhanjing 
Published: January 2020

SummaryThis paper aims to research the seismic performance of steel beam‐column damping joint of Chinese traditional style building. Three specimens of steel beam‐column damping joints with the1:2.6 scale were designed and researched, which included two specimens with viscous damper and one contrast specimen without viscous damper. The experimental study was carried out by cyclic dynamic loading test. The effects of viscous dampers for the steel structure beam‐column joint in Chinese traditional style buildings are analyzed by investigating the hysteretic curves, skeleton curves, strength and stiffness degradation, ductility, overstrength factor, and energy dissipation capacity. The results show that the steel beam‐column joints of Chinese tradition style buildings with viscous damper have better energy dissipation capacity and higher bearing capacity. Based on the experiment, the nonlinear finite element analysis was conducted using the ABAQUS software. The influence of damping coefficient on the behavior of the new damping joint of Chinese tradition style buildings was obtained, and the design suggestions were presented.
Unravelling the identity and nomenclatural history of Zingiber montanum, and establishing Z. purpureum as the correct name for Cassumunar ginger
Authors: Bai Lin , Maslin Bruce Roger , Triboun Pramote , Xia Nianhe , Leong‐Škorničková Jana 
Published: January 2020

AbstractCassumunar is a well‐known and widely cultivated medicinal ginger. Historically, many names have been applied to this species. Over the past two decades, Zingiber montanum (≡ Amomum montanum) has been mostly accepted as the correct scientific name for Cassumunar ginger in spite of numerous discrepancies between the protologue and the plants to which the name was applied. We re‐investigated the identity, taxonomy and nomenclatural history of Z. montanum, Z. purpureum and Z. cassumunar and their synonyms. We show that the correct name for Cassumunar ginger is Z. purpureum and that Z. montanum is a different species. A specimen at C previously regarded as the holotype of A. montanum is not original material, and represents Z. purpureum, which partly explains the confusion between these two names. Zingiber montanum is characterized by scarlet inflorescence bracts and flowers with labellum and lateral staminodes being dark purplish‐red, and mottled cream‐white. Unlike Z. purpureum, Z. montanum is not known in cultivation and has no known medicinal properties. Zingiber newmanii, Z. nudicarpum and Z. peninsulare are placed in synonymy with Z. montanum, expanding the distribution significantly in Southeast Asia and into China. Zingiber purpureum is readily distinguished from Z. montanum by dark red to maroon, purplish or almost brown bracts often with greenish margins, and flowers with cream‐white labellum and lateral staminodes. Zingiber cassumunar, Z. cassumunar var. subglabrum, Z. cliffordiae, Z. paucipunctatum and Z. pubisquamum are treated as synonyms of Z. purpureum. Neotypes are designated for A. montanum and Z. purpureum, and lectotypes are designated for Z. cassumunar, Z. cassumunar var. subglabrum, Z. cliffordiae, Z. peninsulare and Z. pubisquamum.
Nacelle anemometer measurement‐based extremum‐seeking wind turbine region‐2 control for improved convergence in fluctuating wind
Authors: Wu Zhongyou , Li Yaoyu , Xiao Yan 
Published: January 2020

AbstractFor region‐2 operation of wind turbines in practice, the optimal torque gain can deviate from the nominal value because of the variations in turbine and wind conditions. The extremum‐seeking control (ESC) has shown its potential as a model‐free region‐2 control solution in some recent work; however, the ESC with rotor power feedback suffers from undesirable convergence under fluctuating wind. In this paper, we propose to use an estimated power coefficient as the objective function for the torque‐gain ESC, where the hub‐height free‐stream wind speed (FSWS) is estimated with the nacelle anemometer measurement on the basis of the so‐called nacelle transfer function (NTF) between the nacelle anemometer and met‐tower measurement. A sensitivity analysis is performed to quantify the impact of the wind speed estimation error on the estimation of power coefficient. An ESC integrated interregion switching scheme is proposed to avoid the load increase. Simulation results show that, compared with the power feedback‐based ESC, the proposed method can greatly improve the convergence rate of ESC under fluctuating wind, even under relatively large wind speed estimation error. Evaluation for the fatigue loads of wind turbine shows that the proposed control strategy induces mild increase of the wind turbine load.
Noncoding RNAs: New regulatory code in chondrocyte apoptosis and autophagy
Authors: Jiang Siyu , Liu Yi , Xu Bilian , Zhang Yan , Yang Min 
Published: January 2020

AbstractOsteoarthritis (OA) is a bone and joint disease characterized by progressive cartilage degradation. In the face of global trends of population aging, OA is expected to become the fourth most common disabling disease by 2020. Nevertheless, the detailed pathogenesis of OA has not yet been elucidated. Noncoding RNAs (ncRNAs), including long noncoding RNAs, microRNAs, and circular RNAs, do not encode proteins but have recently emerged as important regulators of apoptosis and autophagy of chondrocytes, thereby highlighting a potential role in chondrocyte injury leading to OA onset and progression. We here review recent findings on these regulatory roles of ncRNAs to provide new directions for research on the pathogenesis of OA and offer new therapeutic targets for prevention and treatment.This article is categorized under:RNA in Disease and Development > RNA in DiseaseRNA in Disease and Development > RNA in Development
A landscape for the cosmological constant and the Higgs mass
Authors: Ghorbani Parsa , Strumia Alessandro , Teresi Daniele 
Published: January 2020

Abstract
The cosmological constant and the Higgs mass seem unnaturally small and anthropically selected. We show that both can be efficiently scanned in Quantum Field Theories with a large enough number of vacua controllable thanks to approximated Z2 symmetries (even for Coleman-Weinberg potentials). We find that vacuum decay in a landscape implies weaker bounds than previously estimated. Special vacua where one light scalar is accidentally light avoid catastrophic vacuum decay if its self-cubic is absent. This is what happens for the Higgs doublet, thanks to gauge invariance. Yukawa couplings can be efficiently scanned, as suggested by anthropic boundaries on light quark masses. Finally, we suggest that the lack of predictivity of landscapes can be mitigated if their probability distributions are non-Gaussian (possibly even fractal).
Identification of molecular markers for the Pc39 gene conferring resistance to crown rust in oat
Authors: Sowa Sylwia , Paczos-Grzęda Edyta 
Published: January 2020

AbstractKey messageSix new PCR-based markers for thePc39crown rust resistance gene inAvena sativaL. were developed.Pc39was mapped to Mrg11 of the oat consensus map using BLASTn analysis.AbstractThe aim of this study was the identification of molecular markers for thePc39gene in cultivated oat (Avena sativaL.).Pc39is a major race-specific crown rust resistance gene originally found in an Israeli accession of the wild hexaploidAvena sterilis. The effectiveness of this gene in Europe has decreased in recent years, but is still relatively high and breeding programs would benefit from the availability of molecular markers to aid in its mapping and deployment. The complexity of the oat genome poses a significant obstacle to genetic research. No oat rust resistance genes have yet been cloned, and even the number of relevant molecular markers is very limited. Here, genotyping of a segregating population derived from a cross ‘Celer’ (Pc39)/STH9210 (susceptible) was conducted using RAPD- and SRAP-PCR-based methods, as well as microarray-based DArT™ and next-generation sequencing DArTseq™ techniques. Markers associated withPc39were placed on the hexaploid oat consensus linkage group Mrg11 at 3.7–6.7 cM. Six new PCR-based markers were developed to allow identification of the resistantPc39allele. These tightly linked markers will be useful in marker-assisted selection, with the closest, SCAR_3456624, being within 0.37 cM ofPc39. The newly developed markers could find applications in the fine mapping or positional cloning of this gene. Moreover, easy-to-use PCR-based markers linked toPc39could facilitate the utilization of this gene in oat breeding programs, especially as a component of crown rust resistance gene pyramids.
Algorithms and values in justice and security
Authors: Hayes Paul , van de Poel Ibo , Steen Marc 
Published: January 2020

AbstractThis article presents a conceptual investigation into the value impacts and relations of algorithms in the domain of justice and security. As a conceptual investigation, it represents one step in a value sensitive design based methodology (not incorporated here are empirical and technical investigations). Here, we explicate and analyse the expression of values of accuracy, privacy, fairness and equality, property and ownership, and accountability and transparency in this context. We find that values are sensitive to disvalue if algorithms are designed, implemented or deployed inappropriately or without sufficient consideration for their value impacts, potentially resulting in problems including discrimination and constrained autonomy. Furthermore, we outline a framework of conceptual relations of values indicated by our analysis, and potential value tensions in their implementation and deployment with a view towards supporting future research, and supporting the value sensitive design of algorithms in justice and security.
Lone wolves in competitive equilibria
Authors: Jagadeesan Ravi , Kominers Scott Duke , Rheingans-Yoo Ross 
Published: January 2020

AbstractThis paper develops a class of equilibrium-independent predictions of competitive equilibrium with indivisibilities. Specifically, we prove an analogue of the “Lone Wolf Theorem” of classical matching theory for the Baldwin and Klemperer (Econometrica 87(3):867–932, 2019) model of exchange economies with transferable utility, showing that any agent who does not participate in trade in some competitive equilibrium must receive her autarky payoff in every competitive equilibrium. Our results extend to approximate equilibria and to settings in which utility is only approximately transferable.
Interdisciplinary approach allows minimally invasive, nerve-sparing removal of retroperitoneal peripheral nerve sheath tumors
Authors: Hajiabadi Mohammed Mehdi , Campos Benito , Sedlaczek Oliver , Khajeh Elias , Nikdad Mohammadsadegh , von Deimling Andreas , Mehrabi Arianeb , Unterberg Andreas , Ahmadi Rezvan 
Published: January 2020

Abstract
Purpose
En bloc resection of retroperitoneal peripheral nerve sheath tumors (PNST) is advocated by a variety of surgical disciplines. Yet, microsurgical, nerve-sparing tumor resection might be better suited to improve symptoms and maintain neurological function, especially in cases where patients present with preoperative neurological deficits. However, neurosurgeons, versed in nerve-sparing techniques to remove PNST, are generally unfamiliar with the visceral approaches to retroperitoneal PNST.

Methods
We retrospectively evaluate a series of 16 patients suffering from retroperitoneal PNST. Patients were treated by a unique interdisciplinary approach, combining the visceral surgeon’s skills to navigate the complex anatomy of the retroperitoneal space and the neurosurgeon’s familiarity with microsurgical, nerve-sparing tumor removal. Specifically, we assess whether our interdisciplinary approach is suited to improve preoperative symptoms and maintain neurological function and study whether oncological outcome, surgical morbidity, and operative times are comparable to those reported for “classical” retroperitoneal PNST resection. In addition, we study two cases of suspected PNST that were diagnosed as malignant peripheral nerve sheath tumors (MPNST) after surgery.

Results
Total macroscopic tumor resection was achieved in 14/16 PNST patients. Mean intraoperative blood loss was 680.6 ml (95% CI, 194.3–1167.0 ml) and mean operative time was 162.5 min (95% CI, 121.6–203.4 min). We did not record any major postoperative surgical or neurological complications. A total of 8/11 patients with preoperative pain symptoms reported long-lasting improvement of their symptoms. In terms of oncological outcome, all patients that had been subjected to total tumor removal and for whom follow-up was available, were tumor-free after a mean follow-up of 761.9 days (95% CI, 97.6–1426.0 days). One of the two MPNST patients, who presented with tumor progress 15 months after initial surgery, was subjected to radical re-resection.

Conclusions
Interdisciplinary, nerve-sparing removal of retroperitoneal PNST is well suited to improve preoperative symptoms and maintain neurological function, while achieving an oncological outcome and a surgical morbidity similar to previously reported results for radical retroperitoneal PNST resection. Radical re-resection was feasible in a patient with post hoc MPNST diagnosis.
Exploring pervasive displays for cemeteries and memorial sites
Authors: Häkkilä Jonna , Colley Ashley , Kalving Matilda , Forsman Meri-Tuulia 
Published: January 2020

AbstractThis paper addresses graveyards as a context for designing interactive technology, especially pervasive displays and the presentation of information related to graves and the dead. We present our research containing three user studies: a focus group–based study on perceptions of different display technologies in the cemetery context, evaluation of a gravestone display prototype, and a user study with a graveyard navigator prototype. Whereas, HCI research surrounding death has so far largely focused on an individual’s digital remains, our focus is on the physical graveyard setting. We contribute to understanding the potential impacts and opportunities of interactive technology in this design context. Our salient findings highlight the cultural sensitivity and importance of dignity related to the context, unobtrusiveness of the technology, and concerns for privacy and social acceptability. Concepts taking into account these design aspects were of interest for those researching family histories, and visitors seeking improved navigation for the graveyard.
Terahertz-Based Porosity Measurement of Pharmaceutical Tablets: a Tutorial
Authors: Bawuah Prince , Markl Daniel , Farrell Daniel , Evans Mike , Portieri Alessia , Anderson Andrew , Goodwin Daniel , Lucas Ralph , Zeitler J. Axel 
Published: January 2020

AbstractPorosity, one of the important quality attributes of pharmaceutical tablets, directly affects the mechanical properties, the mass transport and hence tablet disintegration, dissolution and ultimately the bioavailability of an orally administered drug. The ability to accurately and quickly monitor the porosity of tablets during manufacture or during the manufacturing process will enable a greater assurance of product quality. This tutorial systematically outlines the steps involved in the terahertz-based measurement method that can be used to quantify the porosity of a tablet within seconds in a non-destructive and non-invasive manner. The terahertz-based porosity measurement can be performed using one of the three main methods, which are (i) the zero-porosity approximation (ZPA); (ii) the traditional Bruggeman effective medium approximation (TB-EMA); and (iii) the anisotropic Bruggeman effective medium approximation (AB-EMA). By using a set of batches of flat-faced and biconvex tablets as a case study, the three main methods are compared and contrasted. Overall, frequency-domain signal processing coupled with the AB-EMA method was found to be most suitable approach in terms of accuracy and robustness when predicting the porosity of tablets over a range of complexities and geometries. This tutorial aims to concisely outline all the necessary steps, precautions and unique advantages associated with the terahertz-based porosity measurement method.
Vitreous albumin redox state in open-angle glaucoma patients and controls: a pilot study
Authors: Schwab Christoph , Paar Margret , Fengler Vera Heike , Lindner Ewald , Haas Anton , Ivastinovic Domagoj , Seidel Gerald , Weger Martin , Wedrich Andreas , Oettl Karl 
Published: January 2020

Abstract
Purpose
Numerous studies suggest that reactive oxygen species play a crucial role in the development of glaucoma. Since glaucoma patients exhibit posterior vitreous detachment earlier than controls, it has been suggested that reactive oxygen species—increased in glaucoma—also affect the vitreous. In the present study we evaluated the influence of open-angle glaucoma oxidative stress on the redox state of vitreous albumin.

Methods
Albumin redox states of the vitreous and plasma were evaluated in 22 subjects—11 open-angle glaucoma patients and 11 controls—matched for age, gender, and vitreous state. According to the redox state of cysteine-34, albumin can be separated into: human mercaptalbumin (the thiol form), human nonmercaptalbumin1 (a reversible modification due to mild oxidation), and human nonmercaptalbumin2 (an irreversible modification due to severe oxidation).

Results
Albumin of both, the open-angle glaucoma group and the control group, was more oxidized in the vitreous compared to plasma. Furthermore, significantly higher human nonmercaptalbumin1 fractions were found in the vitreous of open-angle glaucoma patients compared to controls. No significant differences were found in the plasma albumin fractions between the groups.

Conclusion
Our results support the hypothesis that oxidative stress plays a crucial role in open-angle glaucoma and that reactive oxygen species in glaucomatous eyes may also affect the vitreous.
Regional land-use and local management create scale-dependent ‘landscapes of fear’ for a common woodland bird
Authors: Whytock Robin C. , Fuentes-Montemayor Elisa , Watts Kevin , Macgregor Nicholas A. , Call Eilidh , Mann Jennifer A. , Park Kirsty J. 
Published: January 2020

Abstract
Context
Land-use change and habitat fragmentation are well known drivers of biodiversity declines. In forest birds, it has been proposed that landscape change can cause increased predation pressure that leads to population declines or community change. Predation can also have non-lethal effects on prey, such as creating ‘landscapes of fear’. However, few studies have simultaneously investigated the relative contribution of regional land-use and local management to creating ‘landscapes of fear’.

Objectives
To quantify the relative contribution of regional land-use and local management to the ‘landscape of fear’ in agricultural landscapes.

Methods
Bioacoustic recorders were used to quantify Eurasian Wren Troglodytes troglodytes alarm call rates in 32 naturally replicated broadleaf woodlands located in heterogeneous agricultural landscapes.

Results
Alarm call rates (the probability of an alarm per 10 min of audio) were positively correlated with the amount of agricultural land (arable or pasture) within 500 m of a woodland (effect size of 1) and were higher when livestock were present inside a woodland (effect size of 0.78). The amount of woodland and urban land cover in the landscape also had positive but weak effects on alarm call rates. Woodlands with gamebird management had fewer alarm calls (effect size of − 0.79).

Conclusions
We found that measures of both regional land-use and local management contributed to the ‘landscape of fear’ in agricultural landscapes. To reduce the impact of anthropogenic activities on ‘fear’ levels (an otherwise natural ecological process), land-managers should consider limiting livestock presence in woodlands and creating traditional ‘buffer strips’ (small areas of non-farmed land) at the interface between woodland edges and agricultural fields.
Enactive becoming
Authors: Di Paolo Ezequiel A. 
Published: January 2020

AbstractThe enactive approach provides a perspective on human bodies in their organic, sensorimotor, social, and linguistic dimensions, but many fundamental issues still remain unaddressed. A crucial desideratum for a theory of human bodies is that it be able to account for concrete human becoming. In this article I show that enactive theory possesses resources to achieve this goal. Being an existential structure, human becoming is best approached by a series of progressive formal indications. I discuss three standpoints on human becoming as open, indeterminate, and therefore historical using the voices of Pico della Mirandola, Gordon W. Allport, and Paulo Freire. Drawing on Gilbert Simondon’s philosophy of individuation we move from an existential to an ontological register in looking at modes of embodied becoming. His scheme of interpretation of the relation between modes of individuation allows us to understand human becoming in terms of a tendency to neotenization. I compare this ontology with an enactive theoretical account of the dimensions of embodiment, finding several compatibilities and complementarities. Various forms of bodily unfinishedness in enaction fit the Simondonian ontology and the existential analysis, where transindividuality corresponds to participatory sense-making and Freire’s joint becoming of individuals and communities correlates with the open tensions in linguistic bodies between incorporation and incarnation of linguistic acts. I test some of this ideas by considering the plausibility of artificial bodies and personal becoming from an enactive perspective, using the case of replicants in the filmBlade Runner. The conclusion is that any kind of personhood, replicants included, requires living through an actual history of concrete becoming.
Rapamycin-Preactivated Autophagy Enhances Survival and Differentiation of Mesenchymal Stem Cells After Transplantation into Infarcted Myocardium
Authors: Li Zhi-hua , Wang Yong-li , Wang Hai-jie , Wu Jin-hong , Tan Yu-zhen 
Published: January 2020

AbstractStem cell transplantation has been limited by poor survival of the engrafted cells in hostile microenvironment of the infarcted myocardium. This study investigated cytoprotective effect of rapamycin-preactivated autophagy on survival of the transplanted mesemchymal stem cells (MSCs). MSCs isolated from rat bone marrow were treated with 50 nmol/L rapamycin for 2 h, and then the cytoprotective effect of rapamycin was examined. After intramyocardial transplantation in rat ischemia/reperfusion models, the survival and differentiation of the rapamycin-pretreated calls were accessed. After treatment with rapamycin, autophagic activities and lysososme production of the cells were increased significantly. In the condition of short-term or long-term hypoxia and serum deprivation, the apoptotic cells in rapamycin-pretreated cells were less, and secretion of HGF, IGF-1, SCF, SDF-1 and VEGF was increased. After transplantation of rapamycin-pretreated cells, repair of the infarcted myocardium and restoration of cardial function were enhanced dramatically. Expression of HGF, IGF-1, SCF, SDF-1, VEGF, HIF-1α and IL-10 in the myocardium was upregulated, while expression of IL-1β and TNF-α was downregulated. Tracing of GFP and Sry gene showed that the survival of rapamycin-pretreated cells was increased. Cardiomyogenesis and angiogenesis in the infarcted myocardium were strengthened. Some rapamycin-pretreated cells differentiated into cardiomyocytes or endothelial cells. These results demonstrate that moderate preactivation of autophagy with rapamycin enhances the survival and differentiation of the transplanted MSCs. Rapamycin-primed MSCs can promote repair of the infarcted myocardium and improvement of cardiac function effectively.