bluuebunny/crossref_metadata_2025_split huggingface dataset:
Depression, anxiety and quality of life in subjects with atopic eczema in a population‐based cross‐sectional study in Germany
Authors: Treudler R. , Zeynalova S. , Riedel‐Heller S.G. , Zuelke A.E. , Roehr S. , Hinz A. , Glaesmer H. , Kage P. , Loeffler M. , Simon J.C. 
Published: December 2019

AbstractBackgroundAtopic eczema (AE) may be associated with several mental health problems. In Germany, existing data from selected patient cohorts may lead to misestimation of the problem.ObjectivesWe aimed to cross‐sectionally determine associations of AE with depression, anxiety, quality of life (QoL) and social interactions in subjects from the population‐based LIFE‐Adult‐Study.MethodsSubjects underwent standardized interviews (medical history) and answered standardized questionnaires [Centre of Epidemiologic studies‐Depression scale (CES‐D), Generalized Anxiety Disorder (GAD‐7), Lubben Social Network Scale (LSNS), Short Form Health Survey (SF‐8)]. We compared data from subjects with AE with those from subjects with selected other chronic/disabling diseases (cardiovascular, diabetes, cancer) and adjusted for selected sociodemographic parameters. Multivariate binary logistic regression was used for categorical variables, linear regression for continuous variables.ResultsOut of 9104 adults included (57% female, median age 54 years), 372 (4.1%) had a history of AE. Compared with controls, subjects with AE showed higher scores for depressive symptoms (9.3% vs. 6.3%; P < 0.001) and anxiety (8.4% vs. 5.6%, P < 0.001). Odds ratio (OR) was 1.5 [CI 1.0; 2.3] (P = 0.031) for depression, which was comparable to OR in patients with a history of cancer (OR 1.6 [1–2.3], P = 0.001. OR for anxiety in AE was 1.5 [1.0; 2.2], P < 0.049, which was slightly higher than in diabetes mellitus (OR 1.2) and stroke (OR 1.4). Other than in diabetes and/or stroke, we did not find a significant association between AE and social isolation. QoL scores were lower in AE than in controls (mean 46.9 vs. 48.0, P < 0.001 for physical and 50.6 vs. 52.5, P < 0.001 for mental components).ConclusionsSubjects with AE showed higher values for depression and anxiety as well as lower QoL scores compared to controls. With regard to depression, odds in AE and cancer were hardly different. Medical care of AE patients should therefore include mental health evaluation and treatment if indicated.
Reproductive physiological characteristics of tropical Celebes eels Anguilla celebesensis in relation to downstream migration and ovarian development
Authors: Hagihara Seishi , Aoyama Jun , Sudo Ryusuke , Limbong Daniel , Ijiri Shigeho , Adachi Shinji , Tsukamoto Katsumi 
Published: December 2019

AbstractDownstream‐migrating (n = 64) and non‐migrating (n = 21) female Celebes eels Anguilla celebesensis were captured from the Poso Lake–River system on Sulawesi Island, Indonesia, and their reproductive physiological characteristics were examined. A histological observation of the ovaries revealed that most non‐migrating eels were at the perinucleolus (43%) or oil‐droplet (48%) stage, whereas most migrating eels were at the early vitellogenic (36%) or midvitellogenic (61%) stage. Transcript levels of gonadotropin genes (fshb, lhb) in the pituitary gland and concentrations of sex steroids [11‐ketotestosterone (11‐KT), testosterone, 17β‐oestradiol (E2)] in blood plasma of migrating eels were significantly higher than those of non‐migrating eels. The fshb messenger (m)RNA levels were lower in perinucleolus and oil‐droplet stages and then significantly increased in the early vitellogenic stage. The lhb mRNA levels in vitellogenic‐stage eels were significantly higher than those in perinucleolus‐ and oil‐droplet‐stage eels. The 11‐KT levels of eels at the oil‐droplet and vitellogenic stages were significantly higher than those of eels at the perinucleolus stage. The E2 levels at the vitellogenic stage were significantly higher than those at the perinucleolus and oil‐droplet stages. These dynamics of the reproductive hormones represented the physiological background of oogenesis in A. celebesensis that has remarkably well‐developed oocytes just before downstream migration.
Antimicrobial and antioxidant properties of burgers with quinoa peptide‐loaded nanoliposomes
Authors: Yekta Mina Mahdavi , Rezaei Mohammad , Nouri Leila , Azizi Mohammad H. , Jabbari Maryam , Eş Ismail , Khaneghah Amin Mousavi 
Published: December 2019

AbstractThis study was aimed to examine the antioxidant (thiobarbituric acid reactive substances [TBARS], peroxide value [PV], and as well as antimicrobial (total bacterial count, Staphylococcus aureus [S. aureus], mold and yeast counts) activities and spoilage indices (total volatile base nitrogen [TVB‐N]) of quinoa peptide‐loaded liposomes incorporated into burger during 12 days of refrigerated storage. Among four prepared batches, the lowest TBARS, PV, and TVB‐N values (0.281 ± 0.05 mg MDA/kg, 3.25 ± 0.34 mEq/kg and 18.65 ± 0.88%, respectively) were correlated with T3 treatment (5 mg/ml peptide). A significant different in the antimicrobial activity among each treatment after 12 days of storage was noted. At the end of refrigerated storage, the highest mean of total bacterial count, S. aureus, mold and yeast (8.36 ± 0.22, 4.19 ± 0.2, and 3.28 ± 0.05 log CFU/g, respectively) were observed in control group, while the lowest corresponded values (3.95 ± 0.2, 2.52 ± 0.25, and 1.52 ± 0.02 log CFU/g, respectively) were noted in T3 treatment. The results showed that the antimicrobial and antioxidant properties of the examined burgers were improved by incorporation of liposomes quinoa peptides encapsulated.
Contextualizing reversal: Local dynamics of the Northern Cities Shift in a Chicago community
Authors: D'Onofrio Annette , Benheim Jaime 
Published: December 2019

AbstractThis paper examines the apparent time evolution of the Northern Cities Vowel Shift among 42 White speakers in one Chicago community. We analyse quantitative patterns of community‐wide vocalic change alongside individual speakers’ lived experiences and attitudes. We find that some features of the Shift are dramatically reversing at the community level, and that changing demographics and social concerns across the community’s history condition which speakers are likely to advance or reverse the Shift. Although some have argued that regionalized sound change reversals reflect speakers’ increasing extra‐local orientations, in this community, we suggest that reversal reflects shifting definitions of racialized localness, including younger speakers’ orientation away from particular emblematic local personae that have become linked with the Shift. We argue that sound changes must be understood in their evolving local contexts, as they can be driven by shifts in the social meanings attached to place‐linked features and in definitions of localness.
Nonspecific expression of fertilization genes in the crown‐of‐thorns Acanthaster cf. solaris: Unexpected evidence of hermaphroditism in a coral reef predator
Authors: Guerra Vanessa , Haynes Gwilym , Byrne Maria , Yasuda Nina , Adachi Souta , Nakamura Masako , Nakachi Shu , Hart Michael W. 
Published: December 2019

AbstractThe characterization of gene expression in gametes has advanced our understanding of the molecular basis for ecological variation in reproductive success and the evolution of reproductive isolation. These advances are especially significant for ecologically important keystone predators such as the coral‐eating crown‐of‐thorns sea stars (COTS, Acanthaster) which are the most influential predator species in Indo‐Pacific coral reef ecosystems and the focus of intensive management efforts. We used RNA‐seq and transcriptome assemblies to characterize the expression of genes in mature COTS gonads. We described the sequence and domain organization of eight genes with sex‐specific expression and well known functions in fertilization in other echinoderms. We found unexpected expression of genes in one ovary transcriptome that are characteristic of males and sperm, including genes that encode the sperm‐specific guanylate cyclase receptor for an egg pheromone, and the sperm acrosomal protein bindin. In a reassembly of previously published RNA‐seq data from COTS testes, we found a complementary pattern: strong expression of four genes that are otherwise well known to encode egg‐specific fertilization proteins, including the egg receptor for bindin (EBR1) and the acrosome reaction‐inducing substance in the egg coat (ARIS1, ARIS2, ARIS3). We also found histological evidence of both eggs and sperm developing in the same gonad in several COTS individuals from a parallel study. These results suggest the occurrence of hermaphrodites, and the potential for reproductive assurance via self‐fertilization. Our findings have implications for management of COTS populations, especially in consideration of the large size and massive fecundity of these sea stars.
Insights into endoplasmic reticulum‐associated degradation in plants
Authors: Chen Qian , Yu Feifei , Xie Qi 
Published: December 2019

SummarySecretory and transmembrane protein synthesis and initial modification are essential processes in protein maturation, and these processes are important for maintaining protein homeostasis in the endoplasmic reticulum (ER). ER homeostasis can be disrupted by the accumulation of misfolded proteins, resulting in ER stress, due to specific intra‐ or extracellular stresses. Processes including the unfolded protein response (UPR), ER‐associated degradation (ERAD) and autophagy are thought to play important roles in restoring ER homeostasis. Here, we focus on summarizing and analysing recent advances in our understanding of the role of ERAD in plant physiological processes, especially in plant adaption to biotic and abiotic stresses, and also identify several issues that still need to be resolved in this field.
Effect of herbal mouthrinses on dental plaque formation and gingival inflammation: A systematic review
Authors: Santi Samantha Simoni , Casarin Maísa , Grellmann Alessandra Pascotini , Chambrone Leandro , Zanatta Fabricio Batistin 
Published: December 2019

AbstractTo evaluate the effect of herbal mouthrinses as an adjuvant to oral hygiene on dental plaque and gingival inflammation in subjects with gingivitis. Searches were conducted in the PubMed/MEDLINE, Cochrane—CENTRAL, EMBASE, Web of Science, LILACS/BIREME, Clinical Trials Registry and grey literature for Randomised Clinical Trials (RCTs) published up to April 2018 without language restrictions. From 4,013 paper found, 20 studies met the eligibility criteria and were included. The herbal mouthrinses achieved significant reductions in dental plaque and gingival inflammation compared to placebo rinses. Five herbal products (Camelia sinensis, Azadirachta indica, Anacardium occidentale Linn, Schinus terebinthifolius and Curcuma longa) showed better results than chlorhexidine in dental plaque and gingival inflammation reductions. However, the unclear risk of bias of most included RCTs precludes definitive conclusions. Therefore, it is necessary to improve the design of future RCT in other reduced potential bias that may affect the degree of precision of treatment outcomes in order to evaluate the effect size and clinical relevance of herbal mouthrinses.
Retracted: Co‐designing technology with people with dementia and their carers: Exploring user perspectives when co‐creating a mobile health application
Authors: O'Connor Siobhan 
Published: December 2019

AbstractAimsTo explore the perspectives of those involved in co‐designing a mobile application with people with dementia and their carers.BackgroundPeople with dementia suffer physical and psychological problems as their illness progresses and require a range of health and social care services to meet their needs. Mobile applications are being developed to support individuals to manage long‐term conditions, but patients and carers are not always involved in designing this technology, which can lead to poor quality health apps. A digital initiative was launched to involve people with dementia and their carers in creating a mobile app that would support communication and enable them to share memories together.DesignAn exploratory, descriptive approach was used.MethodsIn‐depth interviews with people with dementia, their carers, and others involved in co‐creating a mobile health application were conducted. Data analysis was undertaken using the framework approach.ResultsThe views of people with dementia, their carers, and project staff were similar regarding the complexity of the co‐design process, and the value the mobile app had for people with dementia and their families. Being involved in co‐production seemed to have numerous benefits for people with dementia and their carers as they gained new knowledge and skills, friendships, and a sense of achievement in creating a unique app that would benefit many people. The app also appeared useful in stimulating memory and cognitive function, aiding communication, and providing a sense of normalcy for people living with dementia and their carers.ConclusionMobile health applications can facilitate interaction between people with dementia and their carer network that could improve their quality of life. Further research on which co‐design process is best suited to people with dementia and whether technology created via this participatory method is more effective or not in improving health outcomes is required.Implications for practiceNurses should have knowledge of and education about technology and how it can promote health and wellbeing of persons with dementia. Nurses who care for people with dementia and their families should support them in taking part in or leading the design of technologies that meet their needs. Participatory design methods should be taught in nursing education so the profession can provide guidance to patients and their families on co‐creating health products and services
Craniofacial surgery and specific airway problems
Authors: Garcia‐Marcinkiewicz Annery G. , Stricker Paul A. 
Published: December 2019

AbstractInfants and children undergoing craniofacial surgery may present with a wide range of diseases and conditions posing an array of challenges to the anesthesiologist. Optimal perioperative care requires an understanding of these diseases and their impact on airway and anesthetic management. For those children with anomalies affecting airway anatomy, soft tissues of the head and neck, or skeletal mobility, advanced airway management techniques (ie, modalities other than direct laryngoscopy) may be required to secure the airway. Additionally, some craniofacial surgical procedures have direct implications on airway management, such as with Le Fort III midface advancement involving halo distractor application, where the distractor device precludes facemask ventilation. For all of these patients, the anesthetic and airway management plans must be tailored to the surgery being performed, the patient's specific conditions, and take into consideration all phases of perioperative care. In this review, we present some of the more commonly encountered craniofacial abnormalities affecting airway management.
Acute responses of comprehensive gonadosteroids and corticosteroids to resistance exercise before and after 10 weeks of supervised strength training
Authors: Walker Simon , Häkkinen Keijo , Newton Robert U. , Markworth James F. , Pundir Shikha , Haff Guy G. , Cameron‐Smith David , Blazevich Anthony J. 
Published: December 2019

New Findings
What is the central question of this study?
Although acute responses of the principal gonadosteroid and corticosteroid hormones to resistance exercise are well documented, there is no information regarding how the key lower‐concentration intermediary hormones respond and potentially influence these hormonal pathways.
What is the main finding and its importance?
This study provides evidence for cascading conversions of some gonadosteroids, and the data suggest that the testosterone concentration increases independently of these hormones. These findings challenge future studies to determine the exact physiological roles of the lower‐concentration gonadosteroids and corticosteroids during and immediately after resistance exercise.
AbstractResistance training is a potent stimulus for muscle growth, and steroid hormones are known to play a role in this adaptation. However, very little is known about the acute exercise‐induced gonadosteroid and corticosteroid hormone responses, including those of key lower‐concentration intermediate hormones. The present study determined the acute responses of these steroid hormone families using quantitative ultra‐high performance liquid chromatography tandem mass spectrometry after resistance exercise in strength‐trained men. Venous and fingertip blood samples were obtained pre‐, mid‐, 5 min post‐ and 15 min post‐resistance exercise, both before and after 10 weeks of supervised resistance training. The experimental resistance exercise sessions consisted of three sets of 10 repetitions of bilateral leg‐press exercise and three sets of 10 repetitions of unilateral knee‐extension exercise, with 2 and 1 min recovery between sets, respectively. Statistically significant (P < 0.05) increases in the concentration of hormones in the gonadosteroid [including dehydroepiandrosterone (DHEA), androstenedione, testosterone and estrone] and the corticosteroid (including cortisol, corticosterone and cortisone) families were demonstrated after both experimental resistance exercise sessions, irrespective of training status. Correlation analyses revealed relationships between the following hormones: (i) DHEA and androstenedione; (ii) DHEA and cortisol; (iii) androstenedione and estrone; and (iv) 11‐deoxycortisol and cortisol. Testosterone appears to increase acutely and independently of other intermediary hormones after resistance exercise. In conclusion, lower‐concentration intermediary gonadosteroids (e.g. estrone) and corticosteroids (e.g. corticosterone) respond robustly to resistance exercise in strength‐trained men, although it seems that testosterone concentrations are regulated by factors other than the availability of precursor hormones and changes in plasma volume.
Dynamic Trajectory Planning for a Three Degrees-of-Freedom Cable-Driven Parallel Robot Using Quintic B-Splines
Authors: Qian Sen , Bao Kunlong , Zi Bin , Zhu W. D. 
Published: December 2019

Abstract
This paper presents a new trajectory planning method based on the improved quintic B-splines curves for a three degrees-of-freedom (3-DOF) cable-driven parallel robot (CDPR). First, the conditions of positive cables’ tension are expressed in terms of the position and acceleration constraints of the end-effector. Then, an improved B-spline curve is introduced, which is employed for generating a pick-and-place path by interpolating a set of given via-points. Meanwhile, by expressing the position and acceleration of the end-effector in terms of the first and second derivatives of the improved B-spline, the cable tension constraints are described in the form of B-spline parameters. According to the properties of the defined pick-and-place path, the proposed motion profile is dominated by two factors: the time taken for the end-effector to pass through all the via-points and the ratio between the nodes of B-spline. The two factors are determined through multi-objective optimization based on the efficiency coefficient method. Finally, experimental results on a 3-DOF CDPR show that the improved B-spline exhibits overall superior behavior in terms of velocity, acceleration, and cables force compared with the traditional B-spline. The validity of the proposed trajectory planning method is proved through the experiments.
UropathogenicEscherichia coli-Associated Exotoxins
Authors: Welch Rodney A. 
Published: December 2019

ABSTRACTEscherichia coliare a common cause of infectious disease outside of the gastrointestinal tract. Several independently evolvedE. coliclades are common causes of urinary tract and bloodstream infections. There is ample epidemiological andin vitroevidence that several different protein toxins common to many, but not all, of these strains are likely to aid the colonization and immune-evasion ability of these bacteria. This review discusses our current knowledge and areas of ignorance concerning the contribution of the hemolysin; cytotoxic-necrotizing factor-1; and the autotransporters, Sat, Pic, and Vat, to extraintestinal human disease.
Effect of annealing on the morphology and the optical characterization of the AZO:Co thin film prepared by Sol–Gel process
Authors: Mirmohammad-Hosseini-Oushani Seyedeh-Niousha , Zare-Dehnavi Nasser 
Published: December 2019

In this work, the ZnO thin film, the Al-doped ZnO (AZO) thin film (0.98M ZnO, 0.02M Al) and the (Al,Co) co-doped ZnO thin film (AZO:Co) (0.95M ZnO, 0.02M Al, 0.03M Co) were deposited on the glass substrate by the Sol–Gel method. We fabricated a sample of the ZnO thin film, a sample of the AZO thin film and three samples of AZO:Co thin films. The spin-coating was used to deposit thin film on the glass substrate. The ZnO and the AZO thin films were annealed at 450[Formula: see text]C while three samples of the AZO:Co thin films were annealed at 300[Formula: see text]C, 450[Formula: see text]C and 600[Formula: see text]C in air for 60 min, respectively. In order to prepare three samples of the AZO:Co thin films, we deposited the (Al,Co) co-doped ZnO on the glass substrate for 20 s then all samples were per-heated at 80[Formula: see text]C for 10 min. we repeated this deposition process five times for each sample. Finally, three samples were annealed at 300[Formula: see text]C, 450[Formula: see text]C and 600[Formula: see text]C in air for 60 min, respectively. The procedure to prepare of the ZnO and AZO thin films was like the AZO:Co thin films except that the annealing temperature was 450[Formula: see text]C. The structural and optical properties of the thin films were investigated by X-ray diffraction technique, UV-Vis spectrophotometer and Field Emission Scanning Electron Microscopy (FESEM). Results indicated that (Al,Co) co-doping in the ZnO thin film improve the optical transmission while changes in the lattice structure is small with respect to the AZO thin film. Also, the AZO:Co thin film which was annealed at 450[Formula: see text]C exhibited simultaneously the high thickness and high optical transmission.
Ab-initio calculations on the structural and electronic transport properties of five-atom GaN clusters
Authors: Liang Xiao-Chong , Long Xiao-Jiang , Zhang Lin , Zhu Jun 
Published: December 2019

The structural and electronic transport properties of [Formula: see text] clusters are studied based on density functional theory (DFT). Their most stable structures are proved to be planar by the particle swarm optimization (PSO) algorithm, and have decreasing binding energies with the increasing number of Ga atom in clusters. The electronic transport properties of these clusters connected with two Al(1 0 0) electrodes are calculated by combining nonequilibrium Green’s-function (NEGF) with DFT. Most of them have an equilibrium conductance of above [Formula: see text], except for [Formula: see text]. Negative differential resistance (NDR) phenomenon of different level is observed in their I–V curves in bias ranges of from [Formula: see text] to [Formula: see text] V and from 0.7 to 1.1 V.