bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploratory versus experimental design: overcoming the prejudice of ‘data dredging’.
Authors: Pascoe Polly , Jones Sarah Jane 
Published: November 2019

As part of its most recent Efficiency Research Programme, which sought to advance understanding of workforce retention in health and social care, the Health Foundation have provided funding to a team within the Centre for Social Care, Health and Related Research at Birmingham City University. This project proposes to utilise exploratory data analysis techniques to investigate the underpinning contributory factors to nurse retention and ultimately patient safety across 10 acute and 10 mental healthcare providers. Exploratory data analysis techniques do not conform to the accepted hypothesis setting and testing associated with the traditional experimental research design within medicine and consequently, can be subject to criticism. However, these techniques afford bountiful opportunity to generate insight from real-world data; insight that could not be gleamed from experimental designs, therefore they warrant further investigation before being written off as ‘data dredging’.
Exploratory data analysis techniques applied to large datasets that are routinely collected as part of standard care have the potential to revolutionise healthcare. Machine learning and artificial intelligence are becoming common place in everyday life but have been relatively slow to be adopted as a mechanism for improving healthcare. An aspect of the medical community’s reluctance to accept these techniques is a perceived lack of robustness in determining relationships, as hypotheses aren’t typically generated in advance and therefore the process exposes itself to unscrupulous actions where analyses are undertaken until a relationship is found. An element of this programme of work is to develop a set of standards for the application of these techniques to healthcare-generated data including, but not limited to and housing data in open access formats to improve transparency and reporting on findings.
This session seeks to explore these issues with colleagues across disciplines, generating debate regarding novel approaches to complex issues.
PENGARUH MODEL PEMBELAJARAN NUMBERED HEAD TOGETHER TERHADAP HASIL BELAJAR SISWA PADA MATA PELAJARAN MEKANIKA TEKNIK KELAS X TEKNIK KONSTRUKSI DAN PROPERTI SMKN 1 SUMATERA BARAT
Authors: Dwi Putri Rahma , G. Rani, M.Pd Drs. Iskandar 
Published: November 2019

Abstrak - Penelitian ini dilatarbelakangi oleh kesulitan siswa dalam memahami materi Mekanika Teknik. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan model pembelajaran Numbered Head Together (NHT) terhadap hasil belajar siswa pada mata pelajaran Mekanika Teknik di Kelas X Teknik Konstruksi dan Properti (TKP) SMKN 1 Sumatera Barat. Jenis penelitian ini adalah The Non Equivalent Control Group. Subjek penelitian ini adalah siswa kelas X TKP SMKN 1 Sumatera Barat. Pada penelitian ini terdapat 2 kelas yaitu, Kelas X DPIB A sebagai kelas eksperimen dan Kelas X DPIB B sebagai kelas kontrol. Data yang dikumpulkan berupa hasil pretest siswa yang diberikan sebelum perlakuan dan hasil posttest siswa yang diberikan setelah perlakuan. Data yang diperoleh dianalisis menggunakan uji-t untuk melihat perbedaan hasil belajar siswa pada kedua kelas. Berdasarkan perhitungan hipotesis dengan uji-t, diperoleh thitung sebesar 2.226, nilai tersebut lebih besar dari ttabel sebesar 2.042. thitung > ttabel menunjukkan bahwa Ho ditolak dan Ha diterima. Dengan demikian dapat disimpulkan bahwa terdapat perbedaan pada hasil belajar siswa yang menggunakan model NHT dengan model konvensional pada mata pelajaran Mekanika Teknik Kelas X TKP di SMKN 1 Sumatera Barat.Kata kunci: Model Pembelajaran Kooperatif Tipe NHT, Hasil Belajar, Mekanika Teknik
FAKTOR-FAKTOR YANG MEMPENGARUHI MINAT SISWA SMP DAN MTs DALAM MEMILIH JURUSAN TEKNIK KONSTRUKSI DAN PROPERTI DI SMK
Authors: Darma Yulianti Rosita , Syah, M.Pd Dr. Nurhasan 
Published: November 2019

Abstrak – Permasalahan yang ada pada penelitian ini berawal dari rendahnya jumlah siswa SMP dan MTs melanjutkan pendidikan ke Jurusan Teknik Konstruksi dan Properti SMKN 1 Kecamatan Guguak dari tahun 2014 sampai 2018. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang mempengaruhi minat siswa SMP dan MTs dalam memilih Jurusan Teknik Konstruksi dan Properti SMKN 1 Kecamatan Guguak. Penelitian ini adalah penelitian deskriptif dengan jumlah populasi 203 siswa dan sampel 135 siswa. Instrumen pengumpulan data menggunakan angket dengan skala likert yang terdiri dari 4 pilihan jawaban yang terdiri dari 48 butir pernyataan. Uji coba penelitian dilakukan kepada 80 siswa SMPN 1 Kecamatan Guguak dan penelitian dilakukan kepada siswa SMPN 2 Kecamatan Guguak dan MTsN 3 Kabupaten 50 Kota berjumlah 135 siswa. Hasil penelitian mengungkapkan faktor yang dominan mempengaruhi minat siswa SMP dan MTs adalah faktor motivasi dengan persentase 76%. Kata kunci: Faktor Instrinsik, Faktor Ekstrinsik, Minat Siswa, Jurusan Teknik Konstruksi dan Properti
TINJAUAN KETERSEDIAAN SARANA DAN PRASARANA KURIKULUM 2013 DI SMK N 1 SUMBAR PADA WORKSHOP KAYU
Authors: Andesmi Yulia , ST, MT Oktaviani, 
Published: November 2019

Abstrak–Sarana dan prasarana workshop kayu untuk penerapan K-13 di SMK N 1 Sumbar sudah ada tetapi jumlahnya masih terbatas. Oleh sebab itu perlu diketahui ketersediaan serta kondisi sarana dan prasarana bengkel kayu di SMK N 1 Sumbar. Penelitian ini menggunakan metode survey dengan analisis kuantitatif deskriptif. Teknik analisi data data menggunakan perhitungan persentase. Persentase yang dihitung adalah persentase ketercapaian ruang di workshop kayu dengan standar yang ada, persentase ketercapaian kriteria alat di workshop kayu dengan standar yang ada, persentase ketercapaian perabot di workshop kayu dengan standar yang ada. Hasil persentase kemudian dicocokkan dengan skala interval 5 menurut Riduwan untuk mengetahui tingkat ketersediaan sarana dan prasarana. Hasil penelitian ini adalah sarana dan prasarana workshop kayu di SMK N 1 Sumbar belum memenuhi kebutuhan standar sarana dan prasarana sesuai dengan Permendiknas No. 40 tahun 2008 dalam K-13. Hasil penelitian: (1) Sarana dan prasarana pada workshop kayu di SMK N 1 Sumbar sudah tersedia tetapi tidak memenuhi kebutuhan minimal standar sarana dan prasarana K-13. Ketersediaan sarana dan prasarana hanya 41,44% tidak memenuhi standar. (2) Kondisi sarana dan prasarana pada workshop kayu di SMK N 1 Sumbar rata-rata dalam kondisi baik, hanya beberapa alat mesin dalam kondisi rusak ringan.Kata kunci: Ketersediaan Sarana dan Prasarana, Workshop Kayu, Kurikulum 2013
The eligible population of the PARADIGM-HF trial in a real-world outpatient clinic and its cardiovascular risk between 2005 and 2016
Authors: Chen Xiaojing , Schaufelberger Maria , Fu Michael 
Published: November 2019

Background
The PARADIGM-HF trial showed that sacubitril–valsartan – an angiotensin receptor-neprilysin inhibitor (ARNI) – is more effective than enalapril for some patients with heart failure. However, the eligibility of the PARADIGM-HF study to a real-world heart failure population was not well established.

Methods
We made secondary analysis of patients (n = 4872) with heart failure prospectively enrolled in the Swedish Heart Failure Registry from Sahlgrenska University Hospital/Östra Hospital, Sweden during 2005–2016. The eligibility of the PARADIGM-HF trial in the real world was studied based on patients whether they were either fully or partially compatible with the PARADIGM-HF population. Patients were judged to be fully eligible for the PARADIGM-HF trial if they completely met the inclusion and exclusion criteria, and partially eligible if they did not stay on target dose of angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB), despite their having been treated with ACEI/ARB for at least 6 months.

Results
Among patients who had heart failure with reduced left ventricular ejection fraction (≤40%) (HFrEF) (n = 2165), 653 (30%) and 958 (44%) patients were fully and partially compatible with PARADIGM-HF criteria, respectively. In both fully and partially eligible groups, patients were more male. Despite those fully eligible patients being younger (77.6 ± 12.7 vs. 84.0 ± 13.7 years) than noneligible patients, they were much older than in the PARADIGM-HF trial. Moreover, those fully eligible patients had lower all-cause mortality compared with both partially and noneligible patients. However, both fully and partially eligible patients had higher all-cause mortality than that in the PARADIGM-HF trial.

Conclusion
In a real-world outpatient clinical setting, around 1/3–1/2 of HFrEF were eligible for treatment of Sac/Val except that they are older, sicker, and carry higher risk for all-cause mortality than the PARADIGM-HF trial population.
Clinical predictors of pocket hematoma after cardiac device implantation and replacement
Authors: Ferretto Sonia , Mattesi Giulia , Migliore Federico , Susana Angela , De Lazzari Manuel , Iliceto Sabino , Leoni Loira , Bertaglia Emanuele 
Published: November 2019

Aims
Pocket hematoma is a common complication of cardiac implantable electronic device (CIED) procedures. the aim of the study was to research the clinical factors associated with pocket hematoma formation after CIED implantation or replacement and to identify the best perioperative antithrombotic management.

Methods
We retrospectively analyzed 500 consecutive patients who underwent to CIED implantation or replacement at our center from November 2014.

Results
Among our population, 206 patients (41.2%) were on anticoagulant therapy at the time of the intervention: 68 (13.6%) on ongoing Warfarin; 111 (22.2%) on low-molecular-weight heparin (LMWH); and 27 (5.4%) on ongoing direct oral anticoagulants. Antiplatelet therapy was present in 262 (52.4%) patients: in particular, 50 (10%) were on dual antiplatelet therapy, 64 (12.8%) were on single antiplatelet therapy and anticoagulant therapy, whereas 12 (2.4%) were on anticoagulant with dual antiplatelet therapy.
Incidence of pocket hematoma after CIEDs implantation was of 4.6%. Considering the different perioperative anticoagulant strategies, patients on LMWH presented the higher hematoma rate [11/100 patients (11.0%), P < 0.001]. At the multivariate analysis, anticoagulant with dual antiplatelet therapy (P = 0.021, OR 6.3, IC 1.3–30.8), left ventricular ejection fraction (LVEF) less than 30% (P < 0.001, OR 7.4, IC 2.7–20.4), and use of LMWH (P = 0.008, OR 3.8, IC 1.4–10.6) resulted the strongest predictors of pocket hematoma (Hosmer test = 0.899).
Considering replacement procedures, incidence of pocket hematoma was of 4.4%. The incidence was higher after ICD/CRT-D replacement. The majority of pocket hematoma occurred in patients with mechanical valve prosthesis (3/4 cases, 75%, P < 0.001).

Conclusion
The use of LMWH and a low LVEF expose patients to a higher risk of pocket hematoma after CIED procedures. Anticoagulant with dual antiplatelet therapy and LMWH should be avoided.
A High-Altitude Balloon Platform for Space Life Sciences Education
Authors: McKaig Jordan , Caro Tristan , Hyer Alex , Talburt Elizabeth Delgadillo , Verma Sonali , Cui Kaixin , Boguraev Anna-Sophia , Heit Molly , Johnson Aimee , Johnson Emily , Jong Andrew , Shepard Brooke , Stankiewiz Jamie , Tran Nhung , Rask Jon 
Published: November 2019

Abstract
High-altitude balloons (HABs) present a valuable and cost-effective tool for educators and students to access the conditions that are analogous to space and extraterrestrial environments in the Earth’s upper atmosphere. Historically, HABs have been used for meteorological measurements, observation, sampling of aerosols, and exposure of samples to upper atmosphere environments. The Earth’s stratosphere allows researchers access to a unique combination of wideband solar radiation, extreme cold, rarefied air, low humidity, and acute ionizing radiation—conditions that are relevant to space biology research. Here, we describe a reproducible payload for a HAB mission that can be constructed, launched, and retrieved for about $3,000. This general standard operating procedure can be used by educators, community scientists, and research teams working with limited resources.
SIRS Triggered by Acute Right Ventricular Function, Mimicked Septic Shock
Authors: He Yingke , Ong John , Tan Thuan Tong , Goh Brian K. P. , Ong Sharon G. K. 
Published: November 2019

Abstract

Background
The systemic inflammatory response syndrome (SIRS) is a complex immune response which can be precipitated by non-infectious aetiologies such as trauma, burns or pancreatitis. Addressing the underlying cause is crucial because it can be associated with increased mortality. Although the current literature associates chronic heart failure with SIRS, acute right ventricular dysfunction has not previously been reported to trigger SIRS. This case report describes the presentation of acute right ventricular dysfunction that triggered SIRS and mimicked septic shock.

Case presentation
A 70-year-old male presented to the Intensive Care Unit (ICU) with elevated inflammatory markers and refractory hypotension after a robotic-assisted laparoscopic radical choledochectomy with pancreaticoduodenectomy. Septic shock was misdiagnosed, and he was later found to have a pulmonary embolus. Thrombectomy and antimicrobials had no significant efect on lowering the elevated inflammatory markers or improving the persistent hypotension. Through Point of Care Ultrasound (POCUS), right ventricular dysfunction was diagnosed. Treatment with intravenous milrinone improved blood pressure, normalised inflammatory markers and led to a prompt discharge from the ICU.

Conclusion
Acute right ventricular dysfunction can trigger SIRS, which may mimic septic shock and delay appropriate treatment.
Accidental Modopar© Poisoning in a Two-Year-Old Child: A Case Report
Authors: Lahlou Adnane , Benlamkaddem Saïd , Berdai Mohamed Adnane , Harandou Mustapha 
Published: November 2019

Abstract
Levodopa is a dopamine precursor and a mainstay treatment in the management of Parkinson’s disease. Its side effects induce dyskinesia, nausea, vomiting, and orthostatic hypotension. Acute levodopa acute poisoning is uncommon, with only a few reported cases in the medical literature. Treatment of poisoning by levodopa is mainly supportive. The case of a child admitted to a hospital for acute levodopa poisoning is presented in this report.
Trojanische Pferde unserer Zeit - Kritische Essays zur Digitalisierung
Authors: Kaeser Eduard 
Published: November 2019

Wir leben in einer Symbiose mit der Technik. Dabei stösst unser Selbstverständnis an vielen Stellen auf fundamentale Herausforderungen, die eine Neubestimmung des Humanen in seiner technischen Umwelt erfordern. Die Problematik ist oftmals nicht sogleich sichtbar und manifestiert sich erst im Nachhinein als zumeist unbeabsichtigte Konsequenz des Technikgebrauchs. Gerade die Digitalisierung, welche die gegenwärtige Etappe dieser Symbiose kennzeichnet, verkörpert die latente Gefahr, dass der Mensch zum Untertan der Geräte mutiert. Die drängende Frage lautet, ob und inwieweit der Mensch einen Platz zu behaupten vermag, der ihm mehr zusichert als eine Existenz als blosser Geräte-Fortsatz. Gelingt es uns nicht, diesen Platz zu verteidigen, werden wir unseres Menschseins beraubt sein.
Gründe des Bösen - Ein Essay im Anschluss an Kant, de Sade und Arendt
Authors: Noller Jörg 
Published: November 2019

Gibt es Gründe für das Böse, oder geschieht es grundlos? Ist das Böse das gänzlich Unvernünftige? Oder besitzt es gar eine rationale Struktur, die sich weiter verständlich machen lässt? Diesen Fragen geht Jörg Noller anschliessend an Kant, de Sade und Arendt nach – die drei Denker dienen der Untersuchung als historisch-­systematische Koordinaten. Er argumentiert dafür, dass böse Handlungen Willensakten entspringen, die sich rational weiter beschreiben lassen und in unserer individuellen Freiheit gründen.
Aufschlussreich dafür ist Kants Begriff des «Vernünftelns». In dieser weit verbreiteten Aktivität konstruiert sich das Subjekt durch Missbrauch der Vernunft eine Gedankenordnung, in der individuelle Zwecksetzungen als gerechtfertigt erscheinen. Bei de Sade begegnen wir dann einer Vernunft, die im Gegensatz zur Kant’schen nicht das Gute will, sondern das Böse kategorisch befiehlt. Inwiefern aber lässt sich ein solch böses System der Vernunft konsequent denken und leben? Hannah Arendt schliesslich prägte den provokativen Begriff einer «Banalität des Bösen». Inwiefern kann aber das Böse banal sein, wo es uns doch irritiert und verletzt? Anschliessend an diese Gedanken entwickelt Noller eine Theorie des Bösen und analysiert die Gründe, die uns trotz aller Aufklärung immer noch böse handeln lassen.
„Noller legt mit diesem Essay einen eindrucksvollen Überblick der verschiedenen Dimensionen der allgemeinen Scheinhaftigkeit des Bösen vor. […] Die Fülle des von ihm zusammengetragenen Materials sowie die eingängige Aufbereitung desselben leisten einen wichtigen Beitrag auf dem Weg der theoretischen wie persönlichen Aufklärung der Formen des Scheins des Bösen."

S. Böhm, Theologie und Philosophie 3/2020
Übermensch - Plädoyer für einen Nietzscheanischen Transhumanismus
Authors: Sorgner Stefan Lorenz 
Published: November 2019

«In Stefan L. Sorgners Werk wird die tiefgründige Originalität von einem umfassenden Wissen der philosophischen Tradition begleitet. Seine Erforschung der möglichen Bedeutungen des Post-Humanismus ist bereits ein Bezugspunkt, den die zeitgenössische Kultur nicht unbeachtet lassen kann.» Gianni Vattimo, Universität Turin
«Nel lavoro di Stefan L. Sorgner la profonda originalità si accompagna con una vasta conoscenza della tradizione filosofica. La sua esplorazione dei possibili significati del post-umanesimo è ormai un punto di riferimento da cui la cultura contemporanea non può prescindere.» Gianni Vattimo, Università di Torino
Aplikasi Kompos Dengan Aktivator Effective Microorganisms 4 (EM 4) Dan Pupuk Organik Cair NASA Pada Pertumbuhan Bibit Batang Bawah Tanaman Karet (Hevea brasiliensis)
Authors: Fahrin Wandi , Mahdalena Mahdalena , Hamidah Hamidah 
Published: November 2019

Application of Compost With Effective Microorganisms Activator 4 (EM 4) And NASA Fluid Organic Fertilizer At Growth Of Rubber Trunk Bottom Plant (Hevea brasiliensis). This study aims to determine the effect of application of compost fertilizer with activator Effective Microorganisms 4 (EM 4) and the effect of Nasa liquid organic fertilizer application on the growth of rootstock seedling of rubber plant. The study was conducted for 3 months starting from May 5 to August 5, 2015 Loa Janan Ulu Village Kutai Kertanegara Regency. The study used Randomized Block Design (RAK) with 4 x 4 factorial experiment with 3 replications. The first factor is the application of compost treatment consisting of 4 levels, namely: k0 Tanah (topsoil), k1 = Soil: Compost = 1: 1, k2 = Soil: Compost = 1: 2, k3 = Soil: Compost = 1: 3. While the second factor is the application of liquid organic fertilizer NASA consisting of 4 levels, namely: p0 = Control, p1 = 2 ml / L water, p2 = 4 ml / L water, p3 = 6 ml / L water. The result of variance indicated that application of compost fertilizer had a very significant effect on the height of 3 month crop, the increase of stem diameter month 2, month 3, the increase of monthly leaf number 2, month 3. Furthermore significant effect on the increase of plant height month 1, month 2, Stem diameter month 1, and month leaf number increase 1. Application of NASA (P) liquid organic fertilizer had a very significant effect on the parameters of plant height increase in month 2, month, 3, month stem diameter 2, month 3, Month 3. Then the real effect on parameters of plant height month month 1, and the increase of number of leaves month 1. For interaction application of Compost Fertilizer and organic fertilizer Nasa (KxP) no significant effect on parameters of plant height increase month 1, month 2, month 3, the increase of number of leaves month 1, month 2, month 3, the increase of stem diameter month 1, month 2 and month 3. Keywords: Effective Microorganisms 4, Liquid Fertilizer Nasa and Rubber Plants
Pengaruh Pemberian dosis Pupuk P dan K Terhadap Pertumbuhan dan Produksi Bawang Merah (Allium ascalonicum L.) Varietas Bima
Authors: Sinaga Irwansyah Ardianto , Mahdalena Mahdaena , Hamidah Hamidah 
Published: November 2019

The Effect of Dosage of P and K Fertilizer on Growth and Production of Red Onion (Allium ascalonicum L.) Bima Varieties. The purpose of this research is to know the influence of P and K fertilizer application and the interaction of the two treatments on the growth and production of shallot plant. The study was conducted for 3 months, ie from July to October 2016. The research site on land owned by UPTB Samarinda Agriculture Training Center East Kalimantan Province. This study used Randomized Block Design (RBD) with a 3 x 4 factorial experiment consisting of 4 replications. The first factor is fertilizer fertilizer P which consists of 3 levels: namely p0 (without fertilization), p1 (fertilization 1 gr / plant), p2 (Fertilization 1.5 g / plant). The second factor is the dosage of K fertilizer consisting of 4 levels ie k0 (without fertilization) k1 (0.5 g / plant) k2 (1 g / plant) and k3 (1.5 g / plant). The result of this research showed that the treatment of P (P) fertilizer had significant effect on plant height 2 and 3 MST, wet bulb weight and dry bulb weight and no significant effect on plant height of 4 MST, number of leaves, and number of tillers. While the application of K (K) fertilizer had significant effect on plant height and leaf number at age 2 MST and no significant effect on height and number of leaf aged 3 and 4 MST, number of tiller, wet bulb weight and dry bulb weight. There was no interaction between P and K fertilizer application.
PERBEDAAN EFEK MISOPROSTOL DAN OKSITOSIN SEBAGAI PEMATANGAN SERVIKS
Authors: Lasmini Putri Sri 
Published: November 2019

Berbagai penelitian dilakukan untuk menilai efektifitas misoprostol dan oksitosin tersebut, bahkan be- berapa penelitian membandingkan pemakaian misoprostol dan oksitosin sebagai induksi persalinan, Berdasarkan bebagai penelitian tersebut terlihat bahwa tampak pengaruh yang berbeda dari misoprostol dan oksitosin pada fase perturisi mulai pematangan serviks, kontraksi uterus hingga keberhasilan persa- linan. Bila dibandingkan dengan oksitosin, maka misoprostol sebagai obat yang mudah didapatkan, mu- rah dan efektif, sebagai agen pematangan serviks dibanding dengan oksitosin. Penelitian ini merupakan penelitian eksperimental pre-post kontrol group desain untuk menilai proporsi perbedaan efek pemberi- an misoprostol dan oksitosin pada pematangan serviks, Penelitian dilakukan di RS Dr.M.Djamil Padang dan RS jejaring. Waktu penelitian mulai januari 2014 sampai bulan oktober 2014, Variabel bebas adalah pematangan serviks dengan menggunakan misoprostol 25 μg dan drip oksitosin. Variabel tergantung adalah terjadi atau tidaknya pematangan serviks dan penilaian kenaikan Bishop skor. Rata-rata pematan- gan serviks dengan misoprostol lebih tinggi atau lebih besar dibanding dengan oksitosin yaitu 7,0968 ± 2,11904 berbanding dengan 2,5806±3,36427. Secara statistik perbedaan ini signifikan dengan p < 0,05. Misoprostol adalah agen pematangan serviks yang lebih baik daripada oksitosin, Oksitosin sebaiknya diberikan pada serviks yang matang.Kata Kunci : Preeklampsia berat, asam folat, hamil normal.