bluuebunny/crossref_metadata_2025_split huggingface dataset:
Referral for early intervention services in late premature infants	with a NICU experience
Authors: Needelman Howard , Jackson Barbara J. , McMorris Carol , Roberts Holly 
Published: December 2024

Objective: This study investigated the likelihood of referral for early intervention services in premature infants of 34–35 weeks gestation. Study design: All infants 34–35 weeks gestation enrolled in a statewide follow-up program were identified. Referral for evaluation for early intervention was noted and risk factors for this outcome were examined. Results: One-quarter of the infants were referred in the first two years of life. Males and infants with certain congenital anomalies were more likely to be referred. Approximately three quarters of those referred for evaluation for services were found to qualify for services. Over 30% of the infants were lost to follow up. Conclusion: Premature infants delivered at 34–35 weeks have a significant risk for delay mandating evaluation for early intervention services.
Standardizing perinatal consults to improve trainee physician	competency and decrease maternal anxiety
Authors: Sobczak-Hoeft Susan M. , Finer Neil 
Published: December 2024

Objective: To improve trainee physician competency by scripting perinatal consults while concurrently decreasing maternal anxiety and increasing recall. Design: Physicians in neonatal fellowship consulted mothers with impending preterm deliveries between the gestational ages of 22 and 27 weeks using a scripted approach while videotaping the interaction. Mothers were assessed for anxiety before and after the consult as well as after the delivery. Maternal recall was also assessed after the consult. Videotapes were reviewed for the competency of the consulting physician. Results: 14 mothers signed consent for videotaping. Physician competency improved after performing the consult at least once. Maternal anxiety based on an anxiety rating scale test (STAI) decreased in all women after the consult. Recall concerning survival and person performing the consult was highest, and recall concerning modalities of breathing devices and skills needed by a premature infant to go home was lowest. Conclusion: A standardized approach to speaking with mothers with an impending preterm delivery increases the competency of trainees, as well as improves parent-physician communication by increasing recall and decreasing maternal anxiety prior to giving birth.
Medical errors in parenteral nutrition: A comparison of two	computerized programs used in the Neonatal Intensive Care Unit (NICU)
Authors: Hodor Leah Greenspan , Tioseco Jennifer A. , Revenis Mary E. , McCarter Robert , Rais-Bahrami Khodayar 
Published: December 2024

Introduction: Pediatric inpatient populations, including neonates, are at increased risk for clinically significant and/or potentially life-threatening medical errors. Computerized physician order entry (CPOE) holds the promise of reducing medication errors. Special attention must be paid to the match between the specialized needs of the population and the detailed capabilities provided by a CPOE system. As we transitioned from a system designed and developed by a team of pediatric/neonatal sub-specialists for the Children's National Medical Center (CNMC) NICU (TPN 2000) to a more general and adult medicine-based CPOE system (Abacus system, Baxa Corporation, CO), we compared the number and severity of medical errors between the two systems. Method: In Phase I, we reviewed two hundred randomly selected daily TPN orders using the TPN 2000 system, for the number and severity of errors. Specific variables included calcium to phosphorus ratio, osmolality, total calories and dextrose concentration in relation to types of vascular access. Parameters of expected normality were established. Errors were identified and categorized into clinically significant, serious and potentially life-threatening. After 6 months of training on the Abacus system, Phase II began with a review of an additional 200 randomly selected TPN orders from the new system. Results: The most common error was the calcium to phosphorus ratio which accounted for a 4% increase in the number of potentially life-threatening errors (11% errors in TPN 2000 vs. 18% errors in Abacus). Error rates for osmolality were 8.5% during Phase I vs. 0% in phase II. Total calories and dextrose rate errors were not statistically different. Osmolality and dextrose concentration in relation to access showed a 100% improvement in errors in both categories with Abacus vs. the TPN 2000 system. Conclusion: CPOE has the potential to reduce medical errors in the neonatal population. However, a 4% increase in potentially life-threatening errors in calcium to phosphorus ratio seen in our study may support our contention that the sub specialist physicians' input is absolutely essential to the Health Informaticians when designing a new CPOE, modifying an existing one or evaluating and certifying a commercially available or custom developed CPOE system.
Developmental outcome of very low birth weight infants treated	with hydrocortisone for refractory hypotension
Authors: Lattimore Keri A. , Vazquez Delia M. , Barks John D. , Bhatt-Mehta Varsha 
Published: December 2024

Background: Hypotension is a common problem in infants born prematurely and is associated with significant adverse events including increased risk for death, IVH, and adverse neurodevelopment. It has been postulated that relative or absolute adrenocortical insufficiency may be partly responsible for hypotension. This has lead to the widespread use of hydrocortisone as treatment for refractory hypotension. Several studies have documented the ability of hydrocortisone to increase blood pressure in the hypotensive newborn, but there is a paucity of information regarding its long term effect on neurodevelopment. Objective: In 2001, our neonatology group established a protocol for the administration of hydrocortisone for the treatment of hypotension refractory to inotropes. The primary aim of this study is to evaluate neurodevelopment at 12 months corrected age (CGA) as assessed by the Mental development Index and Psychomotor development Index (MDI/PDI) components of the Bayley Scales of Infant Development (BSID). Design/methods: Retrospective matched case-control study of VLBW infants treated with hydrocortisone according to protocol (n = 17) between 2002 and 2005 and BSID score at 12 months corrected age (CGA). Infants were matched on birth weight (BW), ± 300g and none/mild IVH (grades 0, I, II) versus severe (grades III, IV). Results: Hydrocortisone exposed infants were significantly different from the no HC group in gestational age (GA), SNAPPE-II, inotrope score, incidence of PDA , days of mechanical ventilation, and ROP surgery. GA, SNAPPE-II, PDA, and ventilation days were independently significantly correlated with the primary outcome of MDI/PDI. Inotrope score was also significantly correlated with MDI. These variables were included as confounders in the multiple linear regression models. HC use was not a significant predictor of MDI (p = 0.7604) or PDI (p = 0.5593) after adjusting for GA, Inotrope score, SNAPPE-II, ventilator days and PDA by multiple linear regression. Conclusions: HC was not a significant predictor of MDI/PDI scores at 12 months CGA when controlling for a large number of predictors of abnormal neurodevelopment.
Tidal volume delivery and peak inspiratory pressure in babies	receiving volume targeted or time cycled, pressure limited ventilation: A	randomized controlled trial
Authors: Swamy Ravi , Gupta Samir , Singh Jaideep , Donn Steven M. , Sinha Sunil K. 
Published: December 2024

Objective: To study the consistency of tidal volume delivery and the respiratory parameters in babies randomized to either volume-controlled ventilation (VCV) or time-cycled, pressure-limited ventilation (TCPLV). Methods: 90 babies between 24 to 32 weeks' gestation who formed part of the original controlled trial comparing VCV vs TCPLV were studied. As a part of the study protocol, these babies were continuously monitored for key respiratory parameters. Hourly recording of these parameters was obtained for 78 hours or until extubation if it occurred earlier. Consistency of tidal volume delivery and other parameters such as PIP, PEEP, Paw, Cdyn, Ve & FiO $_{2}$ were compared using the Student's t-test with a two-tailed significance level of ⩽0.05. Results: Complete datasets were available on 86 babies, 45 on VCV and 41 on TCPLV. The mean expired tidal volume was slightly higher, and the mean FiO $_{2}$ was lower in the VCV group compared to TCPLV. This was also associated with a higher PIP in VCV compared to TCPLV (16.9 cmH $_{2}$ O vs. 15.3 cmH $_{2}$ O, p = 0.033). However, VCV was associated with significantly higher variability of peak inspiratory pressure and significantly less variability of tidal volume delivery (0.87 mL/kg vs 1.12 mL/kg, p = 0.009). Conclusions: Despite targeting identical exhaled tidal volumes, VCV was associated with consistent tidal volume delivery compared to TCPLV. This may have significance to clinical practice and future research.
Sosialisasi Dan Pendidikan Kesehatan Dalam Optimalisasi Temuan Kasus Tuberculosis Di Kelurahan Mamajang Dalam Kota Makassar
Authors: J Abd Hady , Simunati Simunati , Hariani Hariani 
Published: December 2024

Penelitian Pengabdian kepada Masyarakat (PkM) dalam Program Pengembangan Desa Mitra (PDM) ini bertujuan meningkatkan keberdayaan mitra dalam sosialisasi dan pendidikan kesehatan dalam optimalisasi temuan kasus tuberculosis. Lokasi di Kelurahan Mamajang Dalam Kota Makassar. Mitra utama dalam kegiatan Pengabmas ini adalah Pemerintah Kelurahan, Puskesmas, Posyandu, serta kader kesehatan, dan PMO. Khalayak sasaran adalah kader kesehatan. Pelaksanaan kegiatan Pengabmas dilakukan selama tujuh bulan. Kegiatan intervensi utama adalah focus group discussion (FGD), pendidikan dan pelatihan, serta sosialisasi. Hasilnya, pelaksanaan PkM memainkan fungsi dan peran yang signifikan dalam meningkatkan kompetensi dan keberdayaan Mitra partisipan dalam sosialisasi dan pendidikan kesehatan serta peningkatan temuan kasus Tb. Pelaksanaan FGD, pendidikan dan pelatihan, serta sosialisasi semakin urgen, penting dan strategis dalam mendukung keberhasilan peningkatan kompetensi mitra sebesar 35% pasca PkM. Masih terdapat sejumlah tantangan permasalahan serta hambatan/ kendala teknis dan non-teknis baik yang sifatnya internal maupun eksternal. Oleh karena itu, Tim Pengabmas perlu memiliki kompetensi baik kompetensi teknis dan manajerial, maupun kompetensi strategis dan social dalam mengupayakan solusi atas setiap tantangan permasalahan serta hambatan/ kendala yang dihadapi di lapangan.
Kata kunci: Sosialisasi, pendidikan, tuberculosis, temuan kasus.
Pelatihan Bantuan Hidup Dasar (BHD) Pada Kelompok Masyarakat Di Kelurahan Lompoe Kecamatan Bacukiki Kota Parepare
Authors: Nuralamsyah Muhammad , Nasir Muhammad 
Published: December 2024

Cardiac arrest atau henti jantung merupakan salah satu kondisi kegawatdaruratan yang dapat mengancam jiwa serta mengakibatkan kematian jika tidak ditangani segera, kejadian henti jantung sekitar 360.000 korban banyak ditemukan di luar rumah sakit setiap tahunnya dan 15% sebagai penyebab seluruh kematian. World Health Organization (WHO) menyatakan bahwa penyakit jantung menduduki peringkat pertama dari sepuluh penyakit penyebab kematian di dunia dengan jumlah 7,4 miliar jiwa dari tahun 2000-2012. Pertolongan pertama adalah suatu perawatan yang diberikan sementara menunggu bantuan datang atau sebelum dibawa kerumah sakit atau puskesmas. Kematian akibat cardiac arrrest dapat dicegah dengan melakukan Basic Life Support (BLS) sesuai dengan langkah-langkah chain of survival (Nolan et al., 2010) yang salah satu komponennya adalah resusitasi jantung paru (RJP) yang berkualitas (Gruber et al., 2012). Tujuan kegiatan ini diharapkan peserta mampu memberikan pertolongan pertama saat kejadian pada korban yang mengalami sakit, cedera atau kecelakaan yang membutuhkan bantuan hidup dasar (BHD. Jumlah peserta dalam kegiatan ini berjumlah 27 orang. Pelaksanaan pelatihan diawali dengan sesi pembukaan dan pengenalan pemateri, tim pengabdi, mahasiswa dan juga peserta, Setelah itu dilanjutkan dengan pemberian materi Bantuan Hidup Dasar (BHD), Kegiatan dilanjutkan dengan demonstrasi pemberian kompresi atau tehnik Hands-Only CPR oleh para fasilitator dengan bantuan alat manikin dan audiovisual untuk mempermudah para peserta memahami tehnik dan menguasai ritme pemberian kompresi dalam Resusitasi Jantung Paru. Rangkaian tahapan Bantuan Hidup Dasar dapat dengan mudah dipahami oleh peserta, dan seluruh peserta dapat melakukannya dengan baik.
Kata kunci: Pelatihan, Bantuan Hidup dasar
Peningkatan Pengetahuan Dan Keterampilan Kader Dalam Rangka Peningkatan Kualitas Screening Dan Interpretasi Kejadian Stunting Sesuai PERMENKES RI NOMOR 2 Tahun 2020 Di Kota Makassar
Authors: Hartono Rudy , Andini Mira , Ipa Agustian , Hasanah Besse 
Published: December 2024

Posyandu berperan penting sebagai tempat kegiatan sosial bagi masyarakat untuk memantau pertumbuhan dan perkembangan. Pemantauan tumbuh kembang anak juga dapat dilaukan di Posyandu melalui pengukuran berat badan bayi setiap bulan yang terjadwal secara rutin dicatat pada sistem Kartu Menuju Sehat (KMS). Hambatan terhadap kemajuan anak dalam penambahan berat badan terlihat jelas dari kurva pertumbuhan yang diperoleh dari pengukuran rutin yang tercantum dan dicatat dalam KMS. Peningkatan atau penurunan jumlah anak stunting di bawah usia 5 tahun dapat segera diketahui dalam waktu singkat (beberapa bulan), dengan cepat mengetahui penyebabnya, dan segera menyusun rencana penanggulangannya. Rumusan masalah nonkomersial ini adalah untuk meningkatkan keterampilan kader Posyandu dalam mengukur data BB, PB/TB dan menghitung usia berdasarkan presisi dan akurasi guna meningkatkan kualitas skrining stunting. Metode yang digunakan dalam pengabdian masyarakat adalah team based learning (TBL) dan dukungan eksekutif dalam pelaksanaan kegiatan. Penerimaan materi yang diberikan kepada peserta dapat dikatakan sama baiknya dengan meningkatnya pengetahuan pengukuran antropometri yang akurat dan tepat di Kelurahan Lajangiru Kecamatan Ujung Pandang, Kota Makassar.
Kata kunci: pengetahuan, keterampilan, kader posyandu, screening, stunting
Evaluation of the QRS detector using the Medicom-combi complex for daily monitoring of ECG and blood pressure using the MIT-BIH ECG signal test database
Authors: Khairetdinova G. A. , Fedulaev Yu. N. , Nikolaeva A. M. , Gogichaev V. A. , Evdokimov F. A. 
Published: December 2024

Purpose. To evaluate the accuracy of the QRS complex detectorof the Medicom-combi complex for daily monitoring of ECG and blood pressure using the MIT-BIH ECG signal test database in accordance with the requirements of GOST R IEC60601–2–47–2017, 30324.2.47–2012.Materials and methods. During the tests, the operation of the detector was evaluated using the MIT-BIH Arrhythmia Database, containing 48 records of 30 minutes each. Each selected QRS complex was assigned one of the following types: N (supraventricular complex, normal QRS complex, including bundle branch block), V (ventricular complex), U (complex that experts find difficult to determine) and A (artifact). Rates of sensitivity (Sen), specificity or positive predictive rate (PPR), and overdiagnosis (FPR) were determined.Results. The sensitivity of the QRS complex detector of the Medicom-combi complex for daily monitoring of ECG and blood pressure was 99,98%, and the specificity was 99,87%. The sensitivity of determining ventricular complexes was 99,97%, the specificity of determining ventricular complexes was 99,64%. Overdiagnosis of ventricular complexes does not exceed 0,03%.Conclusion. The Medicom-combi complex for daily monitoring of ECG and blood pressure, designed for long-term ECG monitoring, has sufficient sensitivity and specificity for analyzing Holter ECG recordings, as well as identifying ventricular ectopic complexes.
Effective combination therapy for telogen hair loss
Authors: Shatokhina E. A. , Khaldina M. V. , Mayransaeva S. R. , Klyushina O. Yu. , Bezborodova A. V. 
Published: December 2024

Background. Telogen hair loss is one of the most common forms of alopecia, associated with a disruption in the phases of the hair growth cycle – specifically, the premature transition of the hair follicle into the telogen phase. The primary causes are the influence of triggering factors such as increased stress levels and previous illnesses. The main goal of therapy is to prolong the anagen phase and stimulate hair growth through the use of topical peptides and a multivitamin complex.Objective. To study the effectiveness of a hair growth restoration method in the treatment of telogen alopecia using cosmetic hair growth products and dietary supplements.Methods. The study involved 20 patients diagnosed with telogen alopecia who received treatment with the topical cosmetic products «Time to Grow» and the dietary supplement «Thick and Strong Hair» for 9 weeks. The effectiveness of the treatment was assessed at 3, 6, and 9 weeks after the start of therapy.Results. The analysis of the study showed statistically significant changes in trichoscopy indicators in patients with telogen alopecia, demonstrating the effectiveness of using hair growth cosmetics (p<0.05). At the final assessment point, a reduction in hair loss was observed in 100 % of the subjects, along with improvements in hair quality and volume. A survey evaluating the participants’ subjective experiences demonstrated satisfaction with the treatment and adherence to the therapy.Conclusion. The use of hair growth products and the dietary supplement «Time to Grow» has proven effectiveness in the treatment of telogen hair loss.
Features of sleep disorders in children with psoriasis and comorbid pathologies
Authors: Bychkov S. G. , Murashkin N. N. , Kozhevnikova O. V. , Epishev R. V. , Opryatin L. A. 
Published: December 2024

Purpose of the study. To analyze observations of sleep disorders in children with psoriasis and comorbid diseases.Materials and methods. This article describes clinical cases of sleep disorders in 14- and 15-year-old patients with psoriasis and comorbid diseases (psoriatic arthritis (PsA) and exogenous-constitutional obesity of the 2nd degree) who were treated at National Medical Research Center for Children’s Health of the Ministry of Health of the Russia.Results. Based on the results of collecting anamnesis and polysomnographic study (PSG), it was found that a 14-year-old child with a combination of severe plaque psoriasis (PASI index-21.3 points) and PsA had restless legs syndrome (RLS) of moderate severity, decreased sleep efficiency, and increased sleep fragmentation due to frequent awakenings. A 15-year-old patient with severe plaque psoriasis (PASI-66 score) and grade 2 exogenous-constitutional obesity had moderate obstructive sleep apnea syndrome (OSAS), as well as increased time to fall asleep, reduced sleep efficiency, and increased sleep fragmentation due to frequent awakenings.Conclusions. Sleep disorders are common in children with psoriasis and comorbid pathologies. At the same time, the implementation of a specific variant of dyssomnia or parasomnia depends on both the underlying disease and the concomitant ones.
Teste de antígeno para identificar pacientes assintomáticos/ ou nao, infectados com Sars-Cov-2 - (COVID-19): revisao sistematica
Authors: Lima Leonardo Danthon Carmo de , Ferreira Waltenberg Anunciação , Santana Evonilda de Jesus , Aguiar Eliziandro O. De , Flores Valdeli Rodrigues , Barros Neuza Biguinati de , Araujo Roberto Ataíde Batalha de 
Published: December 2024

O presente artigo e uma revisão sistemática sobre o tema Teste de Antígeno para Identificar Pacientes Assintomáticos/ou não, infectados com SARS-COV-2 (COVID-19). Esta revisão, versa sobre os desafios ao longo do processo de diagnóstico do SARS-COV-2, e a aplicabilidade do teste de antígeno. O objetivo deste ensaio apriori é consubstanciar, sintelizar e correlacionar como diversos autores referenciam esta temática, com o intuito salientar evidências relevantes. Ressaltar impactos importantes provocados pelo SARS-COV-2, ao longo dos anos, bem como evidenciar a eficacia do teste e do diagnóstico precoce para melhores resultados, rumo a novos avanços científicos, bem como implementação de medidas de prevenção. O método utilizado baseou- se em pesquisas bibliográfica através de ferramentas eletrônicas de pesquisa avançada e não avançada das fontes de PubMed Medline, Scielo Scientific Eletronic Library Online), Portal Brasileiro de Informação Científica (CAPES); Web of Science, Google Acadêmico. Pesquisaram-se também os artigos citados nas referências dos textos encontrados e obras clássicas da área, em inglês e português.
ANALISIS KELAYAKAN USAHA DODOL RUMPUT LAUT DI UD. HARKAT MAKMUR KECAMATAN CAKRANEGARA
Authors: NOPIARI IDA AYU 
Published: December 2024

One of the processed seaweeds is in the form of seaweed dodol. People's demand for seaweed dodol is increasing. The use of seaweed for dodol products can provide added value to the food. It is necessary to process seaweed products considering the high nutritional content in them. Therefore, dodol is a favorite food and is quite popular in several regions of Indonesia, including Lombok. Based on the above, research was conducted with the title "Feasibility Analysis of the UD Seaweed Dodol Business. Harkat Makmur” Cakranegara District. The aim of this research is: to analyze the feasibility of seaweed dodol processing business at UD. Harkat Makmur is based on Benefit Cost (B/C) Ratio, Revenue Cost (R/C) Ratio, and Break Even Point (BEP). Based on the results and discussion of research results, it can be concluded that UD Harkat Makmur's seaweed dodol business was declared feasible because it had a B/C ratio value of 3.42 > 1. The B/C ratio value of 3.42 shows that for every Rp. 10,000 spent by UD Harkat Makmur it is estimated that it will make an average profit. -an average of IDR 34,200.