bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis production of laying hens by applying supply chain management on the laying hens industry in Banda Aceh
Authors: Akmal Abdiel Khaleil , Sastra Hasan Yudie , Yaman M. Aman 
Published: May 2020

Abstract
This research is related to the awareness of the people who realize that it will be increasingly important to consume eggs so that it becomes an opportunity for livestock companies to fulfill the people’s demand for chicken eggs. The UPTD of the Non-Ruminant Animal Husbandry as a laying hens industry is very influential on the quality of quality for businesses in producing commercial eggs to be consumed by the people. The UPTD of the Non-Ruminant Animal Husbandry Office continues to improve efficiency in the chain of business activities. The research conducted at the UPTD of the Non-Ruminant Animal Husbandry aims to analyze the supply chain management mechanism in the laying hens’ industry, to analyze supply chain productivity of laying hens commodities, and to examine the benefits and obstacles in applying supply chain management in the laying hens’ industry. The method used to measure productivity is Supply Chain Management. The productivity measurement is based on input identification data, the process of transforming inputs into chicken egg products and the process of sending and distributing chicken eggs. The research produced a supply chain activity flow that occurred in the UPTD of the Non-Ruminant Animal Husbandry went well, consisting of 14 main processes divided into 3 parts, which is identifying source consisting of 4 parts, identifying the make of 5 parts, identifying deliver of 5 parts. The supply chain productivity levels at the UPTD of Non-Ruminant Animal Husbandry are quite good, which are on 73,33 percent and broken eggs 0,44 percent.
Study of harvesting losses for sustainable agricultural production in Southeast Sulawesi (a case study in Konawe district)
Authors: Rusdin  , Witjaksono Julian , Indrasti Rita , Rawung Jefny B. Markus 
Published: May 2020

Abstract
Post-harvest technologies have been produced rapidly, but not at all have been adopted by farmers. Rice harvesting techniques with a group of farmers equipped with rice threshing machines can reduce crop losses and threshing to 5.9%. Moreover, the use of a striper type of rice harvester can reduce crop losses to between 2-3%. In this era of mechanization, there is increasing use of combine harvester at the farm level. This study aims to know the performance of harvest management with combine harvester and post-harvest rice at the farm level and to find out the amount of crop loss with combine harvester and post-harvest rice. The study was conducted in the second crop season in 2017 in Konawe District which is the center of wetland rice in Southeast Sulawesi Province. The results of the study indicated that in general the farmer groups managing the Combine Harvester were not equipped with an organizational structure (73%). The average combine harvester manager is 5-6 people consisting of operators, grain harvesters, grain collectors, and tailor sacks. Unit of agricultural equipment and machinery management (UPJA) works with launchers and harvesting equipment carriers. The ability to harvest in a day is 2 ha, with a harvest time of 3 hours per ha, with fuel consumption of 34.6 liters/ha. While the ability of harvested area in annuals is 35 ha on average. The average weight of yield loss by various planting methods is not too different which is about 0.129 - 0.136 kg. However, the highest percentage of yield loss is in the method of planting tabela (direct scattering) which is equal to 2.084%, this is influenced by the amount of yield obtained from the planting method. While the yield loss due to transportation between distances of less than 500 meters and above 500 meters does not differ much, namely an average of 0.18 kg and 0.21 kg, with an average of 0.2 percent of the average weight before transporting.
Purchasing Decisions Behaviour of Beef Consumer in Kendari, Southeast Sulawesi (Case Study in Mandonga Traditional Market)
Authors: Sani La Ode Arsad , Nafiu La Ode , Kurniawan Widhi , Yunus Febriyani A. 
Published: May 2020

Abstract
Beef sales in the Kendari area are spread across several markets, both modern and traditional markets, one of which is the Traditional Market of Mall Mandonga. Mall Mandonga is one of beef supplies markets in Kendari City, which serve several types of livestock commodity, not only beef but also other types of meat. There are a variety of consumers that need to be mapped to develop a meat sales business in that location. This research is expected to be used as consideration for sellers to develop beef production and marketing in Kendari City, especially in Mall Mandonga Traditional Market. This study was aimed to determine consumer behavior in beef purchasing decisions in Kendari City. The research was conducted at the Mall Mandonga Traditional Market, Kendari City, Southeast Sulawesi, in June-July 2017. The sample population of this study was consumers who bought beef taken accidentally nonprobability as many as 90 people. The measured variable is related to consumer research that buys beef includes the physical characteristics of beef, perceptions of prices, the share of beef, number of purchases, ease of access, seller services, frequency of purchase, number of family members, education level and income level. Data were collected and analyzed descriptively qualitative and quantitative. The results showed that consumer behavior in the decision to buy beef at Mall Mandonga Traditional Market considers: (1) color (53.3%), (2) perception of normal price (80%), (3) purchase frequency 2-3 times in a week (43.3%), (4) total purchases> 2-5 kg (51.1%), (5) combined beef (38.9%), (6) easy access to available beef every day (41.1%) and (7) friendly service (40%).
Social Support and Antibody Responses to Vaccination: A Meta-Analysis
Authors: Uchino Bert N , Landvatter Joshua , Zee Katherine , Bolger Niall 
Published: May 2020

Abstract

Background
Social support and social integration have been linked to lower rates of morbidity and mortality. However, the biological mechanisms responsible for such links need greater attention. Vaccine paradigms provide an integrative window into immune system involvement in the protective influence of social support/integration.

Purpose
The main aim of this article was to conduct a meta-analytic review of the association between social support/social integration and antibody responses to vaccines. Exploratory analyses also examined effect sizes and confidence intervals as a function of several factors to inform future research.

Method
A literature search was conducted using the ancestry approach and with PsycInfo, Medline, and the Psychology and Behavioral Science Collection by crossing the exact keywords of social support or social integration with vaccine or antibodies. The review identified nine studies with a total of 672 participants.

Results
The omnibus meta-analysis showed that social support/social integration was related to higher antibody levels following vaccination, but the average effect size was small and the lower bound of the confidence interval included zero (Zr = 0.06 [−.04, .15]). These results did not appear to differ much as a function of the operationalization of social relationships, participant age, or follow-up period, although effect sizes appeared larger for studies using a primary antigen.

Conclusions
These data provide some evidence that social support may be linked to antibody responses to vaccines. However, effect sizes are mostly small and zero overall effect cannot be ruled out. Future studies would benefit from larger sample sizes and greater consideration of methodological issues associated with secondary immune responses to antigen.
Sleep quality during an overnight on-call program
Authors: Cannon Laura , Ali Dina , Parli Sara E , Martin Craig , Cook Aaron M 
Published: May 2020

Abstract

Purpose
Many institutions deploy pharmacy residents to expand clinical pharmacy services, often in the form of overnight, in-house on-call programs. There is little published evidence regarding pharmacy resident sleep and sleepiness after a night of overnight, in-house on-call activity. A prospective observational cohort study was conducted to determine the relationship between overnight, in-house on-call programs and pharmacy resident sleep and sleep quality.

Methods
The cohort study included both postgraduate year 1 and postgraduate year 2 pharmacy residents. Each resident participated in 10 to 15 overnight on-call shifts. Sleep and sleep quality were assessed using devices worn on residents’ wrists on the nights prior to, during, and after on-call shifts. Resident sleepiness was assessed via the Epworth Sleepiness Scale (ESS) during specified baseline and postcall periods. Univariate and multivariate analysis were used to assess the relationship between measurements of sleep, sleep quality, and sleepiness.

Results
We enrolled a total of 23 residents in the study and recorded data on 269 on-call shifts. Frequently (42.6% of shifts) residents had no time to sleep during overnight on-call shifts. Among those who did have sleep time, the mean sleep time during an overnight, in-house on-call shift was 1.22 (SD, 1.56) hours. Additionally, ESS scores indicated a 2.4-fold increase in sleepiness on the morning after vs the morning before on-call shifts.

Conclusion
Residents often did not sleep while on call. Sleep periods overnight were short and of poor quality. Predictably, residents reported increased sleepiness after an overnight on-call shift. Residents received an average of approximately 10 clinical consultation calls per overnight shift.
Scientific Collaboration During the COVID-19 Pandemic: N95DECON.org
Authors: Rempel David 
Published: May 2020

Abstract
Many academics and researchers have responded to the COVID-19 pandemic by forming on-line national and international collaborative groups to rapidly investigate issues of prevention and treatment. This commentary describes the spontaneous formation of an international team of 115 researchers who summarized the literature on safe methods for decontaminating N95 filtering facepiece respirators in response to the supply crisis. The summary reports and fact sheets on the (www.n95decon.org) website have had more than 200 000 unique visits and the organization’s webinars have reached health care professionals from more than 50 countries. The team is extending its mission to cover other personal protective equipment. The success of these collaborations may alter how scientific questions are tackled in the future.
Do We Have Normative Powers?
Authors: Chang Ruth 
Published: May 2020

Abstract
‘Normative powers’ are capacities to create normative reasons by our willing or say-so. They are significant, because if we have them and exercise them, then sometimes the reasons we have are ‘up to us’. But such powers seem mysterious. How can we, by willing, create reasons? In this paper, I examine whether normative powers can be adequately explained normatively, by appeal to norms of a practice, normative principles, human interests, or values. Can normative explanations of normative powers explain how an exercise of the will can afford us special freedom in determining our reasons? I argue that normative approaches to answering this question prove to be inadequate. To vindicate the thought that normative powers can make our reasons ‘up to us’, we need an altogether different approach to understanding them, one that is located not in the normative but in the metaphysical. I end the paper by sketching a metaphysical explanation of normative powers. This metaphysical defence of normative powers provides a window into a different, more agent-centered way of thinking about rational agency.
ThETA: transcriptome-driven efficacy estimates for gene-based TArget discovery
Authors: Failli Mario , Paananen Jussi , Fortino Vittorio 
Published: May 2020

Abstract

Summary
Estimating efficacy of gene–target-disease associations is a fundamental step in drug discovery. An important data source for this laborious task is RNA expression, which can provide gene–disease associations on the basis of expression fold change and statistical significance. However, the simply use of the log-fold change can lead to numerous false-positive associations. On the other hand, more sophisticated methods that utilize gene co-expression networks do not consider tissue specificity. Here, we introduce Transcriptome-driven Efficacy estimates for gene-based TArget discovery (ThETA), an R package that enables non-expert users to use novel efficacy scoring methods for drug–target discovery. In particular, ThETA allows users to search for gene perturbation (therapeutics) that reverse disease-gene expression and genes that are closely related to disease-genes in tissue-specific networks. ThETA also provides functions to integrate efficacy evaluations obtained with different approaches and to build an overall efficacy score, which can be used to identify and prioritize gene(target)–disease associations. Finally, ThETA implements visualizations to show tissue-specific interconnections between target and disease-genes, and to indicate biological annotations associated with the top selected genes.

Availability and implementation
ThETA is freely available for academic use at https://github.com/vittoriofortino84/ThETA.

Contact
vittorio.fortino@uef.fi

Supplementary information
Supplementary data are available at Bioinformatics online.
Integrating multi-OMICS data through sparse canonical correlation analysis for the prediction of complex traits: a comparison study
Authors: Rodosthenous Theodoulos , Shahrezaei Vahid , Evangelou Marina 
Published: May 2020

AbstractMotivationRecent developments in technology have enabled researchers to collect multiple OMICS datasets for the same individuals. The conventional approach for understanding the relationships between the collected datasets and the complex trait of interest would be through the analysis of each OMIC dataset separately from the rest, or to test for associations between the OMICS datasets. In this work we show that integrating multiple OMICS datasets together, instead of analysing them separately, improves our understanding of their in-between relationships as well as the predictive accuracy for the tested trait. Several approaches have been proposed for the integration of heterogeneous and high-dimensional (p≫n) data, such as OMICS. The sparse variant of canonical correlation analysis (CCA) approach is a promising one that seeks to penalize the canonical variables for producing sparse latent variables while achieving maximal correlation between the datasets. Over the last years, a number of approaches for implementing sparse CCA (sCCA) have been proposed, where they differ on their objective functions, iterative algorithm for obtaining the sparse latent variables and make different assumptions about the original datasets.ResultsThrough a comparative study we have explored the performance of the conventional CCA proposed by Parkhomenko et al., penalized matrix decomposition CCA proposed by Witten and Tibshirani and its extension proposed by Suo et al. The aforementioned methods were modified to allow for different penalty functions. Although sCCA is an unsupervised learning approach for understanding of the in-between relationships, we have twisted the problem as a supervised learning one and investigated how the computed latent variables can be used for predicting complex traits. The approaches were extended to allow for multiple (more than two) datasets where the trait was included as one of the input datasets. Both ways have shown improvement over conventional predictive models that include one or multiple datasets.Availability and implementationhttps://github.com/theorod93/sCCA.Supplementary informationSupplementary data are available at Bioinformatics online.
Specific responses of cuckoo hosts to different alarm signals according to breeding stage: a test of the offspring value hypothesis
Authors: Wang Jiaojiao , Yang Canchao 
Published: May 2020

Abstract
The selective pressure exerted by avian brood parasites forces their hosts to evolve specific defense strategies. When subject to brood parasite attack, avian hosts will often emit alarm calls. To date, few studies have examined whether and how host responses to different alarm calls indicative of different enemies vary with the host’s breeding stage. We carried out alarm call playback experiments during both the egg and nestling stages of the oriental reed warbler Acrocephalus orientalis, a host of the common cuckoo Cuculus canorus. The playback exemplars were selected from recorded alarm calls of the warbler to the presence of common cuckoos, sparrowhawks Accipiter nisus, and oriental turtle doves Streptopelia orientalis, which represented brood parasite, predator, and harmless control, respectively. The results showed that the oriental reed warblers did not discriminate alarm calls issued to different intruder types, but the intensity of the response was significantly higher in the nestling stage than in the egg stage. Attack behavior related to sparrowhawk alarm calls was absent in the egg stage, but aggressive behavior increased dramatically and exceeded the attack frequency in response to the cuckoo alarm call in the nestling stage, implying a shift in the tradeoff between the parents’ own survival and the loss of offspring. Alarm calls attracted a larger number of conspecifics than members of other species. In general, the oriental reed warbler had consistently stronger responses to different alarm calls in the nestling stage than in the egg stage, supporting the offspring value hypothesis.
Impact of ineffective esophageal motility on chemical clearance in patients with gastroesophageal reflux symptoms
Authors: Dao Hang Viet , Matsumura Tomoaki , Kaneko Tatsuya , Takahashi Satsuki , Tokunaga Mamoru , Oura Hirotaka , Ishikawa Kentaro , Akizue Naoki , Kikuchi Atsuko , Fujie Mai , Saito Keiko , Okimoto Kenichiro , Maruoka Daisuke , Nakagawa Tomoo , Arai Makoto , Kato Jun , Kato Naoya 
Published: May 2020

Summary
Ineffective esophageal motility (IEM) is the most common manometric abnormality in gastroesophageal reflux disease (GERD). However, the impact of IEM on esophageal chemical clearance has not been fully investigated. This study aimed to determine the impact of IEM on esophageal chemical clearance in patients with GERD. A total of 369 patients with GERD symptoms who underwent upper endoscopy and high-resolution manometry (HRM) test were retrospectively analyzed. The relationship between IEM and erosive esophagitis was examined. In addition, the impact of IEM on chemical clearance was examined in patients who underwent an additional combined multichannel intraluminal impedance–pH (MII–pH) test. Esophageal chemical clearance capability was evaluated via postreflux swallow-induced peristaltic wave (PSPW) index and acid clearance time (ACT). Of 369 patients, 181 (49.1%) had esophageal motility disorders, of which 78 (21.1%) had IEM. The proportion of IEM patients in those with erosive esophagitis and those without were 16.2% and 21.7%, respectively, and no significant difference was observed (P = 0.53). After excluding patients other than those with IEM and normal esophageal motility, 64 subsequently underwent MII–pH test. The median values of the PSPW index in the IEM and normal esophageal motility group were 11.1% (4.2%–20.0%) and 17.1% (9.8%–30.6%), respectively. The PSPW index was significantly lower in the IEM group than in the normal esophageal motility group (P &lt; 0.05). The median ACT values in the IEM group and normal esophageal motility group were 125.5 (54.0–183.5) seconds and 60.0 (27.2–105.7) seconds, respectively. The ACT was significantly longer in the IEM group than in the normal esophageal motility group (P &lt; 0.05). In conclusion, IEM was found to be associated with chemical clearance dysfunction as measured against the PSPW index and ACT. As this condition could be a risk factor for GERD, future treatments should be developed with a focus on chemical clearance.
Subxiphoid uniportal bilateral lung wedge resection
Authors: Negi Takahiro , Suda Takashi , Tochii Sachiko , Hoshikawa Yasushi 
Published: May 2020

Abstract
Subxiphoid uniportal bilateral lung wedge resection, in which all manipulations are performed via a 3-cm wound positioned below the xiphoid process, can be performed in the supine position without the patient having to change positions. It also enables one-stage bilateral lung resection. We report the surgical procedure and initial results of subxiphoid uniportal bilateral lung wedge resection. A 3-cm transverse incision was made 1 cm caudally below the xiphoid process. A port for uniportal surgery was inserted. After CO2 insufflation at 8 mmHg, the lung was grasped and lifted with bent grasping forceps, and by bending the tip of a stapler, the surgeon resected the affected portion of the bilateral lungs. In this approach, there is one incision, no intercostal nerve damage and bilateral surgery can be performed in the same procedure; therefore, the technique may have the benefit of lesser invasiveness for the patient. Furthermore, a detailed comparison of subxiphoid uniportal bilateral lung wedge resection with the one-stage lateral intercostal approach with a larger subject sample is needed.
Omentum support for cardiac regeneration in ischaemic cardiomyopathy models: a systematic scoping review
Authors: Wang Hogan , Roche Christopher D , Gentile Carmine 
Published: May 2020

Abstract

OBJECTIVES

Preclinical in vivo studies using omental tissue as a biomaterial for myocardial regeneration are promising and have not previously been collated. We aimed to evaluate the effects of the omentum as a support for bioengineered tissue therapy for cardiac regeneration in vivo.

METHODS
A systematic scoping review was performed. Only English-language studies that used bioengineered cardio-regenerative tissue, omentum and ischaemic cardiomyopathy in vivo models were included.

RESULTS
We initially screened 1926 studies of which 17 were included in the final qualitative analysis. Among these, 11 were methodologically comparable and 6 were non-comparable. The use of the omentum improved the engraftment of bioengineered tissue by improving cell retention and reducing infarct size. Vascularization was also improved by the induction of angiogenesis in the transplanted tissue. Omentum-supported bioengineered grafts were associated with enhanced host reverse remodelling and improved haemodynamic measurements.

CONCLUSIONS
The omentum is a promising support for myocardial regenerative bioengineering in vivo. Future studies would benefit from more homogenous methodologies and reporting of outcomes to allow for direct comparison.