bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accuracy assessment of dental age estimation with the Willems, Demirjian and Nolla methods in Spanish children. Comparative cross-sectional study.
Authors: Cortés Marta Macarena Paz , Rojo Rosa , García Esther Alia , Martínez Maria Rosa Mourelle 
Published: February 2020

Abstract
Background: The objective of this study was to evaluate and compare the validity and accuracy of the Willems, Demirjian and Nolla methods in predicting chronological age in a Spanish ethnicity population. Methods: A sample of 604 orthopantomographs of Spanish children aged 4 to 14 years was evaluated by two independent evaluators. Descriptive statistics were applied to calculate the chronological age and dental age, presenting the mean and standard deviation. The difference between dental age and chronological age was calculated for each method. A positive result indicated an overestimation and a negative figure indicated an underestimation. The Wilcoxon test for paired data and Spearman's correlation coefficient were applied by age groups and gender to compare the chronological age and dental age of each method (that of Willems, Demirjian and Nolla). Statistical tests were performed at a 95% confidence level. Results: The interexaminer agreement was 0.98 (p = 0.00), and the intraexaminer agreement was 0.99 (p = 0.00). The Willems method significantly overestimated the age of boys (0.35 years (0.93)) and girls (0.17 years (0.88)). The Demirjian method significantly overestimated the age of boys (0.68 years (0.95)) and girls (0.73 years (0.94)). The Nolla method significantly underestimated age in boys (0.44 years (0.93)) and girls (0.82 years (0.98)). Conclusions: In the Spanish population, the use of the Demirjian method for legal and medical purposes is frequent. This study reveals that the Willems method is more appropriate due to its greater precision in estimating dental age.
Gut microbiota differences between psoriatic arthritis and undifferentiated arthritis patients
Authors: Hsu Chung-Yuan , Kuo Ho-Chang , Su YU-JIH 
Published: February 2020

Abstract
Introduction Psoriatic arthritis (PSA) is a form of immune-mediated inflammatory arthritis. Studying the gut microbiota of PSA patients may offer new insights into the pathophysiology of this inflammatory joint disease. We designed a prospective study to examine gut microbiome from patients with PSA, primarily with enthesitis and dactylitis, and compared the data with undifferentiated arthritis patients (NO PSA), without enthesitis or dactylitis.Methods We enrolled nine PSA patients and 10 NO PSA patients in this study. The fecal samples were investigated by using 16S rRNA amplicon sequencing, followed by bioinformatics and statistical analyses. Results None of the available objective clinical laboratory data could differentiate PSA from the NO PSA subgroup. The microbiota result shows that Family: XIII_AD3011 is significantly higher in NO PSA patients than PSA patients’ stool samples (p=0.039). Megasphaera elsdenii in the PSA was 10000 times higher than in the NO PSA group.Conclusion Our results demonstrated high intra-group homogeneous and high inter-group heterogeneous microbiota. The clinical symptoms of either enthesitis or dactylitis link to the specific microbiota in the current study. In the future, a larger cohort and thorough biochemical study is needed for confirmation.
A Strategy Framwork For Deciding Between Alliances Or Acquisition Of Johnson & Johnson Pharmaceutical Company (Case Study: Strategy Farmwork of Johnson & Johnson And Cipla Inc in The Production of Anti-Infectious Drugs)
Authors: Aniqoh Nur Aini Fitriya Ardiani 
Published: February 2020

This study analyzes a strategy framwork for deciding between alliances or acquisition of Johnson Johnson Pharmeutical Company. The general objective of this study is to determine the appropriate corporate development strategy of Johnson Johnson to strengthening the position in the area of infectious diseasese to help the mankind to get the best anti infectious drugs with the affordable price. Infectious diseases is a second leading killer worldwide, it is consist of HIV/ AIDS, TB, Hepatitis C, etc. Infectious diseases have caused an unprecedented global health crisis. The Asia division of Johnson Johnson plans to invest in open innovation through more research partnerships and collaborative efforts that connect the medical and academic communities to its RD centers especially in infectious disease. The data used in this research is data result of observation, literature study and interviews with senior executives and consultants who handle comparable decision of JohnsonJohnson. The data show that alliance is preferrable. High uncertainty within the environment is the most influencing factor to determine this choice. Due to the industry nature, many RD collaborations in developing particular drugs are established. By defining the proper governance structure the collaboration can limit the risk of losing in the learning race and core competencies spillover while obtaining the knowledge access to the counterparty. The Strategic alliance between Johnson Johnson and Cipla Inc can help them toughen the corporate development strategy. Because of their similarities in the production of anti-infectious drugs, they can cooperate to penetrate emerging markets and do several RD collaborations to create a competitive advantage.
Nickel Allergy of the Skin and Beyond
Authors: Gergovska Malena , Darlenski Razvigor , Kazandjieva Jana 
Published: February 2020

Background:Hypersensitization to nickel is one of the most common contact allergies in the modern world and it is considered to be a major cause of contact dermatitis, especially for hand eczema.Objective:The aim of this paper is to describe many faces of the nickel allergy and to find out different diagnostic, potential strategies for treatment and prevention in hypersensitized patients. A personal clinical experience with practical clinical cases of contact dermatitis to nickel has also been presented.Methods:Electronic databases on this topic was carried out using PubMed-Medline.Results:The literature review identified many articles reporting for nickel contact allergy and pointing the metal as number one allergen in the frequency of positive skin patch test reactions in a large population worldwide. Herein, a summary of the current understanding and evidence on nickel allergy with practical approach and proposed recommendations to the dermatologist, general practitioner, and the allergist were prepared.Conclusions:The prevalence of nickel allergy represents an important socio-economical and health issue. Metal is one of the most common sensitizing agents worldwide. The morbidity due to this metal represents the allergic contact dermatitis and it is constantly growing in many countries. There are also cases of systemic allergic contact dermatitis, where they could be easily misdiagnosed as adverse drug reactions, which lead to delay of the correct diagnosis and inappropriate treatment.
A (Speculative) View on Allicin and Primary Metabolism: An Additional Way to Affect Cell’s Physiology
Authors: Sarfraz Muhammad , Gruhlke Martin C.H. 
Published: February 2020

Background:Allicin from garlic is known for different medical uses for centuries. One important explanation for these effects is the chemical reactivity of allicin as a thiosulfinate towards thiol-groups and the modification of thiol-groups by thioallylation.Objective:It has been shown that thioallylation can inhibit the enzymatic function of proteins. In different organisms, the thioallylated proteins upon allicin treatment have been examined. It was found, especially in human T-cell lymphocytes (Jurkat-cells), that the glycolysis is a major target for allicin. Here, we briefly discuss that affecting the primary metabolism is a possible part of allicin’s physiological functions and might be, both from therapeutic and nutraceutical view, of particular interest for the application of allicin as an active principle of freshly damaged garlic.Conclusion:This might, in summary, explain a possible further mode of action of allicin on cells by changing the metabolism as the central life process and thus influencing the overall structure of the physiological processes in the cell, which can lead to the multitude of consequences caused by allicin.
Mitología jurídica en nuestra América: resignificar el discurso jurídico para un derecho intercultural
Authors: Fonseca Sandoval Jose Daniel 
Published: February 2020

El presente artículo tiene como propósito la crítica del discurso jurídico moderno en Nuestra América, desde la perspectiva de la mitología jurídica. La tesis principal consiste en que la ciencia jurídica, al negar o ignorar su fundamento mítico, encubre las relaciones desiguales de poder y de saber que definen y construyen el discurso del derecho. Desde una posición teórico-crítica nuestroamericana, se revisará, en primer lugar, la concepción del derecho como discurso y campo social, así como la emergencia de las zonas del no-ser. En segundo lugar, se abordará el fundamento mítico de la ciencia jurídica y dos ejemplos de configuraciones míticas del discurso del derecho. Finalmente, el artículo concluye que, para realizar un derecho intercutural, decolonial y para la emancipación, se necesita una apertura discursiva de mitos y cosmologías, acompañada de la reivindicación de saberes jurídicos y derechos alternativos.
Editorial
Authors: Bernal Olarte Angélica 
Published: February 2020

Nos complace presentar el Número 8 de la Revista Razón Crítica de la Facultad de Ciencias Sociales de la Universidad Jorge Tadeo Lozano. Este es un número especial porque implica el cierre y, al mismo tiempo, el inicio de un nuevo ciclo. La Revista empezó en 2016 y completa ya ocho números, siete de los cuales han estado a mi cargo como editora. En estos tres años hemos tenido avances muy importantes como la inclusión de nuestra publicación en directorios tales como CLASE, ERIH PLUS, Flacso Argentina, Mendeley, MIAR, PKP Index, ROAD, SHERPA/RoMEO, SSRN, Ulrich's Periodicals Directory; así como en las bases de datos DOAJ, Fuente Académica Plus (EBSCO) y Redib. Hemos publicado 53 artículos escritos en un 45% por autores y autoras extranjeras. En total hemos tenido 67 autoras/es, 60% hombres y 40% mujeres. Así mismo, se han publicado tres números monográficos: el número 4, sobre Derechos Humanos y Justicia Transicional que tuvo como editora a la profesora Martha Gutiérrez; el número 6, sobre el Acto narrativo en la era digital, editado por el profesor German Duarte; y finalmente, el especial sobre China que contó con Enrique Posada como co-editor.
Revisiting the ‘Recognition’ of the Palestinians’ Right to Self-Determination: Peoples as Territories
Authors: Sakran Shadi 
Published: February 2020

‘[B]ehind every Palestinian there is a great general fact: that he once – and not so long ago– lived in a land of his own called Palestine, which is now no longer his homeland.’ The question of whether the Palestinian people, as a people, are entitled to exercise the right to external self-determination has been highly controversial over the years. Divided scholarly research, particularly regarding the attitude of the State of Israel which, at time of writing, has not yet explicitly recognized the Palestinian peoples’ right to emerge as an independent State, serves as evidence to this claim. In 2004, the ICJ in the Wall Advisory Opinion observed that the Palestinians’ right to self-determination is no longer in issue. This observation serves as the benchmark for this paper to revisit the identification of a people under international law. This paper critically examines whether constitutive and declaratory theories of recognition in statehood can assist in understanding the concept of a people in the law of self-determination. While concluding that neither theory of recognition is satisfactory, this paper argues that application of the right to self-determonation, within and beyond the colonial context, is inevitably linked to the territory peoples inhabit. Although the relationship between peoples and territories should come as no surprise, the key element in determining a people is not based on the people but on the status of the territory they inhabit.
PELATIHAN PENGELOLAAN PAUD DI PADUKUHAN SEKITAR UNIVERSITAS NEGERI YOGYAKARTA
Authors: Hayati Nur , Pamungkas Joko , Syamsudin Amir 
Published: February 2020

Pengelolaan Pendidikan Anak Usia Dini yang sesuai dengan kurikulum dan prinsip pembelajaran bagi anak usia dini diupayakan dapat mengoptimalkan perkembangan anak. Pelaksanaan pendidikan tidak serta merta dijalankan tanpa menganut pandangan tertentu atau hanya mengandalkan kemauan dan semangat mengembangkan PAUD saja. Pendidikan akan memiliki arah, tujuan dan pelaksanaan yang baik jika dari awal telah direncanakan secara matang. Filosofi merupakan salah satu hal yang harus dijadikan pijakan ketika akan menyelenggarakan pendidikan agar arah pelaksanaannya sistematis dan sesuai dengan tuntutan lingkungan. Pelatihan pengelolaan PAUD yang dilaksanakan di padukuhan sekitar UNY dihadiri sekitar 37 peserta kader PAUD. Metode kegiatandilaksanakan dalam bentuk ceramah, diskusi, dan praktek pengemasan pembelajaran. Kegiatan pelatihan dilaksanakan selama 2 hari, yaitu hari pertama pada tanggal 8 Juni 2013 dan hari kedua pada tanggal 22 Juni 2013.Kegiatan pelatihan ini terbagi ke dalam 3 (tiga) sesi. Kata Kunci: Pelatihan, Pengelolaan PAUD, Filosofi PAUD
NADA DIATONIK PADA GELAS KACA TERKAIT TINGKAT PENCAPAIAN PERKEMBANGAN MOTORIK HALUS PADA ANAK USIA DINI
Authors: Wulandari Rina 
Published: February 2020

Penelitian ini bertujuan untuk mendeskripsikan nada-nada diatonik yang terdapat pada berbagai macam gelas kaca. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Hasil penelitian menunjukkan bahwa gelas kaca yang menghasilkan nada diatonik adalah karakter gelas yang menghasilkan nada diatonis adalah jenis gelas Pilsener Glass, Water glass, dan gelas anggur. Nada dihasilkan berdasarkan gelas yang berbahan cenderung tipis, yaitu 2 mm. Gelas kaca dapat menghasilkan nada yang nyaring dan terukur secara diatonik yaitu dengan cara memukul yaitu pada posisi 1/3 bagian atas dari gelas. Karakter gelas yang tidak menghasilkan nada diatonik adalah gelas yang ketebalan bibir gelas lebih dari 2 mm dan adanya tangkai pada tubuh gelas.Implikasi penelitian ini diantaranya adalah: 1) tingkat tebal-tipis bahan pembuat gelas kaca mempengaruhi kualitas nada diatonik yang dihasilkan gelas. Gelas kaca berkualitas nada diatonik berbahan kaca yang digunakan cenderung tipis transparan sehingga dapat menghasilkan bunyi nyaring saat dipukul dan 2) pelaksanaan pembelajaran pada anak usia dini perlu memperhatikan tingkat keamanan penggunaan gelas kaca ini (rentan pecah) yang disarankan untuk anak mulai usia 4 tahun. Kata kunci: nada, diatonik, gelas kaca, motorik halus
Mathematics Fun Day for Orphanage of Pemerhati dan Penguatan Anak Negeri Kota Langsa
Authors: Amalia Rizki - 
Published: February 2020

The aim of this Community Service is to give motivation of study and basic knowledge of counting in mathematics and its application. The target of this service is children in orphanage of Pemerhati dan Penguatan Anak Negeri Kota Langsa. This service using direct approach method, speech, and practical activities. The approach method is performed with problem observation which is faced by chidren in the orphanage related to mathematics learning. Presentations about how to do quick and right count are performed in each group of elementary school (SD), junior high school (SMP) and senior high school (SMA) as well as its games in order to find the first rank of these group. This Service got a great response from the children. The observation of this community service’s implementation can be concluded as: (a) The level of partisipation from our mitra for this community service “Mathemtics Fun Day” gives possitive affect for this community service and (b) The programm implementation of this service is able to improve knowledge and learning motivation in mathematics, especially in algebra operation. Therefore, this program is useful to increase the grade of mathematics subject in their school.
Peningkatan Hasil Belajar IPS Melalui Penerapan PBL Berbantuan Powerpoint Pada Siswa SMPN 1 Gemolong Kabupaten Sragen
Authors: * Muzaini, Muhsinatun Siasah Masruri 
Published: February 2020

Penelitian ini bertujuan untuk meningkatkan: aktivitaspembelajaran IPS melalui penerapan problem based learning (PBL) berbantuan PowerPoint, dan hasil belajar IPS siswa SMPN 1 Gemolong Kabupaten Sragen.Jenis penelitian ini adalah penelitian tindakan kelas. Subjekpenelitian adalah siswa kelas VIIIC SMPN 1 Gemolong Kabupaten Sragen.Jenis tindakan yang diterapkan adalah pembelajaran dengan pendekatan PBL berbantuan powerpoint. Teknik pengumpulan data yang digunakan adalah dokumentasi, observasi, wawancara dan tes. Data dianalisis dengan statistik deskriptif. Analisis ini untuk menjelaskan perkembangan proses pembelajaran dan hasil belajar sebelum dan setelah diterapkan pembelajaran dengan PBL.Hasil penelitian ini menunjukkan bahwa setelah dilakukan tindakan pembelajaran dengan menerapkan PBL berbantuan powerpoint: 1) terjadi peningkatan aktivitas pembelajaran sebesar 57% pada siklus I, dan 5% pada siklus II; 2) terjadi peningkatan hasil belajar sebesar 57,58% pada siklus I, dan 6,06% pada siklus II; 3) terjadi peningkatan ketuntasan belajar sebesar 36,37% pada siklus I, dan 12,12% pada siklus II; dan 4) peningkatan sikap dan keterampilan kerja sama kelompok sebesar 24,24% pada siklus II. Kata Kunci: hasil belajar, pembelajaran IPS, Problem Based Learning, media PowerPoint
Kajian Terhadap Perkawinan antar Orang Berbeda Agama di Wilayah Hukum Kota Yogyakarta
Authors: * Setiati Widihastuti, Sri Hartini, Eny Kusdarini 
Published: February 2020

Penelitian ini bertujuan untuk mengidentifikasi kemungkinan dilangsungkannya perkawinan antar orang berbeda agama di wilayah hukum Kota Yogyakarta, dan mengidentifikasi putusan Hakim Pengadilan Negeri atas permohonan perkawinan antar orang berbeda agama di Catatan Sipil Kota Yogyakarta. Metode yang digunakan adalah deskriptif kualitatif. Wawancara dan dokumentasi dipilih sebagai teknik pengumpulan data. Subyek penelitian ditentukan dengan teknik purposive, yakni dua orang Hakim dan dua pejabat dari Bidang Pencatatan Sipil Kota Yogyakarta. Analisis data dilaksanakan secara induktif, yang tahapannya terdiri dari reduksi data, unitisasi dan kategorisasi data, display data, kesimpulan serta verifikasi. Dalam simpulan kajian ini dapat dikemukakan bahwa: 1) Perlu dispensasi dari Pengadilan Negeri untuk melangsungkan perkawinan beda agama di wilayah hukum kota Yogyakarta. 2) Sikap Hakim PN Yogya atas permohonan perkawinan berbeda agama: (a) menolak memberikan dispensasi, (b) kemungkinan dapat mengabulkan permohonan dispensasi, apabila Hakim berpendapat UU Perkawinan memang tidak mengatur tentang perkawinan beda agama, sehingga terdapat kekosongan hukum. Kata kunci: perkawinan antar orang berbeda agama, Pengadilan Negeri, Pencatatan Sipil
Assessment of load and quality of logging residues from clear-felling areas in Järvselja: a case study from Southeast Estonia
Authors: Kurvits Vahur , Ots Katri , Kangur Ahto , Korjus Henn , Muiste Peeter 
Published: February 2020

Abstract
The properties of biomass-based fuel and combustion tests showed that logging residues are promising renewable energy sources. The data used in this study were collected from four clear-felling areas in Järvselja Training and Experimental Forest Centre, Southeast Estonia in 2013–2014. Logging was carried out by harvesters in Scots pine (Pinus sylvestris L.), Norway spruce (Picea abies [L.] Karst.), silver birch (Betula pendula Roth.) and black alder (Alnus glutinosa L. Gaertn.) dominated stands with a small admixture of other tree species according to the cut-to-length method and logging residues were placed in heaps. The aim of this research is to assess different characteristics of logging residues (quantity, moisture content, energetic potential, ash content and amount) in clear-felling areas. The highest load of slash was measured on the birch dominated study site, where the dry weight of the logging residues was 29 t ha−1. Only the branch fraction moisture content on the black alder dominated site (35.4%) was clearly different from respective values on other sites (21.6–25.4%). The highest calorific value of the residues was assessed with the residues from the birch dominated site, where in moist sample it was 365 GJ ha−1 and in dry matter 585 GJ ha−1. The heating value of the fresh residues is highest in coniferous trees. The highest ash content in branch segments was registered for the black alder dominated site. Järvselja data indicate higher quality in conifer dominated sites, yet a higher load of logging residues in broadleaf dominated stands.
Remote sensing and sig contribution for the identification of the fracturation influence on the drainage network architecture in the High Ziz River basin, Central High Atlas, Morocco
Authors: Diani Khadija , Kacimi Ilias , ElBelrhiti Hicham , Zemzami Mahmoud , Tabyaoui Hassan , Masmoudi Lhoussaine 
Published: February 2020

Abstract
This study aims to contribute to a better estimation of the density of fractures likely to favour the drainage of surface water in the High Ziz River (HZR) basin. The method adopted consists of the use of different airborne image processing techniques (filtering, enhancement and slope analysis) which allow a good discrimination of image discontinuities (lineaments) that can then be used for producing lineament maps. The influence of these lineaments on the underground flow is then studied. Indeed, it was possible to extract the lineament network, following the exploitation of remote sensing and an objectively completed analog analysis using the PCI Geomatica LINE module and its directional filters (Sobel directional filters by the ACP method), and to extract the hydrographic network of the HZR basin, using the ArcHydro tool. After superimposing these data, their thematic maps (of the lineament and hydrographic network) were developed. In addition, this comparison of the two hydrographic networks and lineament maps showed us very varied flow directions influenced by geological structures, particularly fracturing. The topography of the region also has a secondary impact on flows through the presence of slopes generally oriented towards the SE of the basin. The correlation of the results with the different directions of the orders of the hydrographic network allowed us to identify the potential effects of lineaments on the orientations of surface water circulation. In addition to these results, the realization of the Rose diagram indicated that the dominant trend in lineaments is N90–45N° (NE–SW).
Relief as an important factor in determining priority landscapes: a case study on Polish landscape parks
Authors: Wałdykowski Piotr , Adamczyk Joanna , Cieszewska Agata 
Published: February 2020

Abstract
The practical problems of implementing the Regulation on Landscape Audits (European Landscape Convention, ELC) in Poland are discussed through the topic of landscape relief, on an example of landscape classification of three of Poland’s landscape parks. In the existing landscape typologies, various criteria are proposed, in which relief is usually considered to be one of the leading components. The study was carried out for the purposes of the Landscape Parks Conservation Plans, based on a comparison of the method under the Principles of Landscape Audits and the authors’ method. The results indicate that the landscape types set out in the regulation insuficiently take relief into account, leading to omitting the local specific nature of the terrain. The essential attributes of the terrain in the analysed parks are the morphometry of relief and its genesis. Relief helps to determine the landscape types that are more related to the terrain.