bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatial Distribution of Various forms of Malnutrition Among Reproductive Age Women in Nepal: A Bayesian Geoadditive Quantile Regression Approach
Authors: Vatsa Richa , Ghimire Umesh 
Published: July 2020

Abstract
Background: Confronting the poor nutritional status of women is a major challenge for a developing country like Nepal. This paper presented a critical analysis of factors associated with malnutrition using a Bayesian geoadditive quantile regression approach and assessed spatial variations of malnutrition among Nepalese women. Methods: Data drawn from the 2016 Nepal Demographic and Health Survey was used to assess the spatial distributions of four forms of malnutrition at the provincial level. Spatial and nonlinear components were estimated using Markov random ﬁelds and Bayesian P-splines, respectively. Results: Analysis of 6,159 reproductive age-group women suggests the existence of severe thinness and underweight in rural and among women residing in provinces 2, 5, and Sudurpashchim. Similarly, the likelihood of being obese was prominently high in urban residents and women in Bagmati, and Gandaki. Richest quintile women, followed by women in richer households, were more likely to be obese and overweight. Consistent findings were reported for underweight (e.g., women from poorer households, and women from households without improved toilet facility). Accessibility of mass media (e.g. newspaper, radio, TV) had inconsistent association with the forms of malnutrition. As women aged, likelihood of being overweight and obese became higher. Conclusion: Inconsistent distribution of various forms of malnutrition existed across provinces in Nepal, revealing dissimilar inﬂuence of other socio-economic variables. Health policy precisely addressing province- and location-specific under- and over-nutrition is, therefore, recommended. Elements of hygiene using mass media could be helpful to reach younger and the most impoverished sect of population.
Midwives&rsquo; Integration of Post-Abortion Manual Vacuum Aspiration in the Democratic Republic of Congo: A Mixed Methods Case Study &amp; Positive Deviance Assessment
Authors: Bourret Kirsty Marie , Larocque Sylvie , Hien Amélie , Hogue Carol , Muray Kalum , Lukusa Aurélie Thethe , Ngabo Abel Minani 
Published: July 2020

Abstract
Scientific AbstractBackground: This collaborative research with the Professional Association of Congolese midwives (SCOSAF) in the province of Kinshasa, Democratic Republic of Congo sought to understand how midwives have integrated manual vacuum aspiration (MVA) for post abortion care.Methods: A positive deviant approach to Creswell’s mixed method comparative case study design was used to identify midwives who have integrated MVA post training and to explore enabling factors. Case group comparisons of positive and non-positive deviant midwives provided further interpretations.Results: All 102 midwives invited to be surveyed were recruited. They included 34% who reported practicing MVA post training. No statistical significance was found between the two groups’ demographics and facility type. Overall, groups had positive attitudes regarding midwifery, MVA, and legalization of abortion. Positive deviant midwives demonstrated and described more confidence and competence to practice and teach MVA. They were more likely to identify as teachers and overcome interprofessional barriers by teaching MVA to physicians, medical students and other midwives and position themselves as experts during post abortion emergencies.Conclusion: Results provided important insight to midwives’ integration of post abortion care in Kinshasa. Strategies used by positive deviant midwives in emergencies allowed them to navigate challenging contexts in order to practice MVA, while simultaneously increasing the credibility of their profession and the dissemination of evidenced-based MVA practice. Programs designed to work with and promote positive deviant midwives as knowledge brokers could be tested for its overall impact on the diffusion of midwifery led MVA to improve access to safe respectful reproductive care.
The Pain Prevalence, Characteristics and Related Factors of Non-Small Cell Lung Cancer (NSCLC) Referral to Palliative Care Service
Authors: Gu Xiaoli , Gao Huifeng , Chen Menglei , Liu Minghui , Zhang Zhe , Cheng Wenwu 
Published: July 2020

Abstract
Background：This study is to analyze the occurrence and clinical characteristics of cancer pain in advanced non-small cell lung cancer (NSCLC) patients who referral to palliative care treatment, as well as correlation between pain performance and clinical characteristics, laboratory indicators, and previous treatment.Methods ：Advanced NSCLC patients referred to the Palliative Care Unit (PCU) from January of 2016 to December of 2018 were included in our study. The Brief Pain Inventory (BPI) was used to evaluate cancer pain (CP). Results: Of 54 (56.7%) patients reported with pain, there were 23 patients (42.6%) who suffered from severe pain (score >=7) at the admission. There was a significant difference in the frequency of pain between patients with and without bone metastasis (p= 0.006), between patients with more than two sites and non-more than two sites metastasis (p=0.032). Patients received epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI) had lower pain prevalence (p=0.033). Patients with bone metastases (p=0.005), with more than two metastases (p=0.022) and those with higer C-reactive protein (CRP) index (p= 0.012) had higher mean scores of pain, with significant differences. Conclusions:Our study showed the general characteristics, pain performance and related factors of advanced NSCLC patients who referral to palliative care service. This study confirmed that these patents’ clinical manifestations of pain were correlated with bone metastasis, metastasis with more than two sites, elevated CRP, and the EGFR-TKI usage. Whether there is a certain potential connection between these factors deserves further study.
Probing afterslip and viscoelastic relaxation following the 2015 Mw 7.8 Gorkha earthquake based on the 3-D Finite Element Model
Authors: Su Lina , Shi Fuqiang , Gan Weijun , Su Xiaoning , Yan Junyi 
Published: July 2020

Abstract
We analyzed GPS coordinate time series from 34 continuous GPS stations in Nepal and 5 continuous GPS stations in South Tibet of China, and extracted the first 4.8 years postseismic displacements after the 2015 Mw7.8 Gorkha earthquake. With the longer duration GPS observations, we found that postseismic displacements mainly exhibit the southward and uplift movement at the epcientral area. To study the postseismic afterslip and viscoelastic relaxation, we then built 3-D spherical finite element model (FEM) with heterogeneous material properties and surface topography across the Himalayan range, accounting for the strong variations of material properties and surface elevation along central Himalayan arc. The sophisticated FEM is more realistic and perform better than the flat layered earth model. On the basis of it, we reveal that the predicted viscoelastic relaxation of cm level is opposite to the observed postseismic deformation; the postseismic deformation with viscoelastic relaxation deducted is well explained by afterslip downdip of coseismic rupture, which indicates the afterslip is still dominant during 4.8 years postseismic deformation after the 2015 Mw7.8 Gorkha earthquake; The lack of slip on a shallow portion and western segment of the MHT during and after the 2015 Gorkha earthquake implies continued seismic hazard in the future.
Multiple dural arteriovenous fistulas in the superior sagittal sinus region with reversible parkinsonism and urinary incontinence as rare presentations: a case report
Authors: Yu Weiwei , Jin Haiqiang , You Qian , Zhang Haoran , Huang Yining 
Published: July 2020

Abstract
Background: Dural arteriovenous fistula (DAVF), characterized by abnormally direct connections between meningeal arteries and meningeal veins or dural venous sinuses, is a rare subtype among the intracranial arteriovenous malformations. Although the clinical manifestations of DAVF are very variable depending on the locations and size of venous drainage, parkinsonism and urinary incontinence are rarely reported. Here, we present a rare case with parkinsonism and urinary incontinence secondary to DAVF. Case presentation: A 50-year-old man was admitted for a progressively worsening weakness of his left lower limb over a year with urinary incontinence for four months. Neurological examination revealed rigidity and bradykinesia of the left upper limb without an obvious tremor. Magnetic resonance imaging exhibited diffuse white matter hyperintensities in bilateral centrum semiovale. Cranial magnetic resonance venography revealed extensive tortuous venous malformations. Digital subtraction angiography exhibited multiple bilaterally distributed DAVF in the superior sagittal sinus, supplied by bilateral occipital arteries and superficial temporal arteries. In the one year follow-up, the patient with multiple DAVF bilaterally distributed was completely cured after endovascular treatment according to the symptoms and the follow-up imaging results. Conclusion: this report enriches the clinical presentations of DAVF with parkinsonism and urinary incontinence, which is a crucial diagnostic clue to be aware of the possibility. Moreover, these rare symptoms can be relieved by timely endovascular treatment.
Fabrication of Al2O3-coated BiFeO3 particles and fine-grained ceramics with improved electric properties
Authors: Bai Peijia , Li Yutong , Wang Gang , Han Jiao , Wei Yongxing , Li Mingwei , Mao Duan , Zeng Yiming 
Published: July 2020

Abstract
(1-x)BiFeO3@xAl2O3 ceramics with x = 0, 2.5, 5, and 7.5 mol% were prepared via the Stöber coating method. The effects of Al2O3 coating on microstructure, dielectric, and ferroelectric properties had been investigated. At x = 5 and 7.5, the samples had a great Al2O3 coating effect. XRD results indicated that excessive Al2O3 coating increased the formation of secondary phases (Bi2Fe4O9 and Bi24A12O39). After the coating of Al2O3, the samples had higher relative density and decreased loss tangent. Compared with the pure BiFeO3 sample, the Al2O3-coated samples had improved Bi-O strength, less oxygen vacancy, and the reduction of Fe3+ was decreased. The leakage current density decreased gradually. At x = 5, the sample had the highest Pr value (1.53 μC/cm2). These electric properties changes were ascribed to the generation of secondary phases, the fine grains, and the fewer vacancies.
THE VALUE OF CYTOREDUCTIVE SURGERY FOR ISOLATED LYMPH NODE RECURRENCE OF OVARIAN CANCER
Authors: Mamajonov H. I. , Nikoghosyan S. O. , Shevchuk A. S. 
Published: July 2020

The purpose of the study was to undertake a systematic literature review regarding the role of cytoreductive surgery in treatment of recurrent ovarian cancer, as well as to summarize available data on various current studies and estimate indications for secondary cytoreduction in recurrent ovarian cancer with isolated lymph node involvement.Material and Methods. The search for relevant sources was carried out in PubMed, Gynecol Oncol, Medline, NCCN, Elibrary systems; publications were included from January 2006 up to March 2019. Of the 87 studies found, 26 were used to write a systematic review.Results. Ovarian cancer (OC) remains the leading cause of death from gynecological cancer. The initial treatment for IC-IV stages of OC includes surgical cytoreduction followed by platinum-containing chemotherapy. The best outcomes are observed in patients, in whom complete cytoreduction has been achieved. Despite this fact, most patients develop relapses and the 5-year survival rate is about 30 %. The frequency of lymph node involvement in patients with recurrent OC is not reliably known; isolated lymph node recurrence is reported to occur in 5–32 % of patients. To date, the problem regarding the extent of lymph node dissection in treatment of OC recurrence is still unsolved. In our paper we review the available data concerning the role of secondary cytoreductive surgery for isolated lymph node recurrence of ovarian cancer.Conclusion. Isolated lymph node recurrence of ovarian cancer may indicate a more favorable prognosis and has a less aggressive pattern of OC relapse. The role of secondary cytoreduction in this context is not fully understood, but this category of patients may be one of the most suitable for surgical treatment of ovarian cancer recurrence.
GENETIC POLYMORPHISM OF RETROPERITONEAL MYXOID LIPOSARCOMA
Authors: Volkov A. Yu. , Safronova V. M. , Nered S. N. , Lyubchenko L. N. , Stilidi I. S. 
Published: July 2020

Objective: to detect new molecular genetic markers and therapeutic targets in retroperitoneal myxoid liposarcoma.Material and Methods. DNA samples isolated from tumor tissue and obtained from formalinfixed paraffin-embedded (FFPE) slides were used. DNA was extracted using the GeneRead DNA FFPE Kit (50) (Qiagen). High-throughput next generation sequencing (NGS) using the GeneReader Actionable Insights Tumor Panel (GRTP – 101X) on the QCI Analyzer version 1.1 platform (Qiagen) was used for molecular genetic analysis of 12 genes involved in carcinogenesis: KRAS, NRAS, KIT, BRAF, PDGFRA, ALK, EGFR, ERBB2, PIK3CA, ERBB3, ESR1, RAF1.Results. Targeted sequencing of retroperitoneal extra-organ myxoid liposarcoma demonstrated genetic heterogeneity. Our study was the first to describe mutations and polymorphic variants in genes, such as EGFR, PIK3CA, ALK, BRAF, ERBB2 / 3, ESR1, KIT, PDGFRA in myxoid liposarcoma.Conclusion. This study demonstrated a wide range of molecular genetic rearrangements in retroperitoneal extra-organ myxoid liposarcoma. Synonymous mutations in the EGFR (Q787Q) and PDGFRA (P567P) genes were detected in all cases (100 %). Missense mutations in the ERBB2 gene (P1170A) and synonymous mutations in the ALK (G845G) and BRAF genes were identified in 75 % of cases. Missense mutation in the PIK3CA gene (I391M) was detected in 25 % of cases. The gene polymorphisms presented in this paper are most likely involved in the carcinogenesis of retroperitoneal myxoid liposarcoma. Further studies with larger patient groups and multivariate analysis of long-term treatment results are required.
The 1990s on the RTS Screens: Analysis of the Domestic Television Series and the Audience Attitudes
Authors: Simeunović-Bajić Nataša , Vujović Marija , Pavlović Dragana 
Published: July 2020

In the cultural memory of peoples or individual groups, there is always a certain temporal point around which complex socio-political discourses develop. In Serbia, it was the 1990s. Many studies analyzed this period from different and opposite perspectives, but research on TV programs from that era has been rather neglected. This paper focuses on TV series and audience attitudes in order to determine their role in this period. The methodology is based on secondary data from previously conducted research since it is difficult to determine the audience's attitudes towards a serial program that was broadcasted in the 1990s from this temporal distance. The reports from the RTS (Radio Television of Serbia) Research Center were used, and a brief analysis of individual achievements from that period was made to define a more general picture of the television series offered. The methods used were: historical analysis, content analysis and comparative analysis, therefore, the qualitative approach dominates.
Ideology has long been identified as an increasingly common component of popular content, so particular attention was paid in this paper to detailed analysis and „reading between the lines.“ Although at first glance it was expected that clear ideological representational matrices would be recognized in TV series broadcasted in the 1990s, our research shows that this is not the case. Detailed analysis provided answers to the newly discovered meanings of a complex and never-completed process of cultural formation within the peculiarities of everyday life in a territory that was largely isolated and at a time pressed by various phenomenological and axiological categories. That everyday life was human, lively and inevitable, and its representation in the series does not cover the semantic paradigm of the most difficult of all times in contemporary Serbian history. In a deeper reading of the attitudes and thinking of the audience, it is noticed that the perception of the socio-political crisis of the time was projected on the wishes of the audience, as it pleaded for more fun, optimism and humanity, which became part of the basic viewing preferences. More than that, viewers have expressed a need for much more love content in future recorded series, which shows a certain measure of saturation, on the one hand, and a culmination of optimism and relaxation regarding the expectations of the serial content, on the other. The audience's desires were turned toward distraction from reality, wars, sanctions and dark topics.
Historic hydraulic works: paradigms of traditional good water governance, integrity and sustainability
Authors: Megdiche-Kharrat Feirouz , Zheng Xiao Yun , Moussa Mohamed , Famin Zhang , Angelakis Andreas N. 
Published: July 2020

Abstract
The first Water Integrity Forum in Delft, The Netherlands (June 2013), defined the core of water integrity as ‘the integrity of people and institutions governing water resources, decision making that is fair and inclusive, honest and transparent, accountable and free of corruption’. Historic hydraulic structures are man-made ancestral water systems that helped sedentism and the emergence of cities where the resource is rare or partly available. The scope of the study is to present seven examples of historic hydraulic structures from different geographic contexts, as diverse as South America, Europe, the Middle East and the Far East, as paradigms of indigenous knowledge in water governance. They are traditional gravity-flow water supplying systems whose functioning is based on eco-friendly and sustainable techniques such as the exploitation of surface and runoff water with ensuring minimal water losses, community-based management by already set rules upon common agreements, the preservation of ecological landscapes and the practice of traditional agriculture. This paper highlights those systems and connects their specifications to economic, social, political and environmental dimensions for good water governance and to water integrity key principles, Transparency, Accountability, Participation and Anti-corruption, in a way to explore their potential to do so.
Prevalence and Factors Associated with Lower Limb Amputation in Patients Hospitalized for Diabetic Foot: a Cross-sectional Study
Authors: Ndong Abdourahmane , Tendeng Jacques Noel , Diao Mohamed Lamine , Dia Diatou Gueye , Dia Amadou Diop , Ba Arona , Diallo Adja Coumba , Dia Diago Anta , Ngouamba Blaise Magloire , Ma Nyemb Philippe Manyacka , Konaté Ibrahima 
Published: July 2020

Background:
Diabetes is the leading cause of non-traumatic amputation of the lower limb. Several factors
associated with amputation are described in the literature, but they remain not well studied in our context.

Objectives:
Our aim is to determine the prevalence and factors associated with amputation in patients hospitalized for
diabetic foot.

Methods:
This is a prospective cross-sectional study performed over the period from December 1, 2017 to June 30, 2018.
The patients included were those hospitalized for trophic disorders of the foot in patients with type 2 diabetes. The studied
parameters were: epidemiological, diagnostic, therapeutic and evolutionary data. An univariate analysis and then a binary
logistic regression identified the factors associated with lower limb amputation.

Results:
We included 53 patients. A lower limb amputation was performed in 8 patients (prevalence of 15.1%). Univariate
analysis found as factors associated with major amputation: advanced age (p = 0.031); male gender (p = 0.003); use of
traditional treatment (p = 0.036); non-compliance with the diabetic diet (p = 0.016); stage D of the University of Texas
(UT) Classification (p = 0.029); grade ≥ 2 of the UT Classification (p = 0.002). Logistic regression finds only the
following two variables as independent factor associated with amputation: male gender (p = 0.004, OR = 36.1 and CI =
3.2-402.9); stage D of the UT classification (p = 0.014, OR = 21.3 and CI = 1.8-244.2).

Conclusion:
Controlling these factors would allow better management of diabetes to avoid complications.
Seaweed Extract Improves Carbohydrate Metabolism in Overweight and Obese Adults
Authors: Elidottir Anita S. , Sveinsdottir Kolbrun , Ingadottir Bergros , Geirsdottir Olof G. , Jonsson Palmi V. , Rothenberg Elisabeth , Hardardottir Ingibjorg , Freysdottir Jona , Ramel Alfons 
Published: July 2020

Background:
Background: Obesity is characterized by chronic low-grade inflammation and associated
with type 2 diabetes. Seaweed is one of the largest producers of biomass in the marine environment
and is a rich arsenal of functional ingredients that may possess the potential to prevent type 2 diabetes.

Objective:
The aim was to investigate the effects of seaweed extract on glucose metabolism and
markers of inflammation in overweight and obese individuals.

Methods:
Participants (N=76, ≥40 years, body mass index ≥25 kg/m2) who volunteered for this 10-
week randomized, controlled, doubly blinded intervention study, were randomized into an intervention
group (seaweed extract, 3 capsules=1200 mg/day) or a control group (placebo, 3 capsules/day).
The extract derived from the brown seaweed bladder wrack (Fucus vesiculosus). At baseline and
endpoint of the study, fasting samples were analysed for blood glucose, insulin, inflammation markers,
liver enzymes and creatinine (renal function).

Results:
Drop out was 11.8% and not significantly different between groups. Fasting blood glucose
and insulin were improved at the endpoint in the intervention group, but no changes were observed in
the control group (corrected endpoint differences between groups: glucose=0.61 mmol/L, P=0.038;
insulin=0.72 μU/L, P=0.038). Measures of inflammation, liver enzymes and renal function did not
change significantly during the study.

Conclusion:
Ingestion of seaweed extract over 10 weeks improves glucose metabolism without affecting
measures of inflammation, liver function or renal function.