bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on RFID indoor location algorithm based on WPA-BP
Authors: REN JIE , JIANG LINGXIAO , ZHAO Ruinan 
Published: December 2024

Abstract

The conventional RSSI-based RFID positioning algorithm is extensively employed for indoor positioning. To enhance the accuracy of position coordinates and minimize errors, this paper proposes an innovative RSSI-based RFID indoor positioning algorithm that integrates the Wolf pack algorithm (WPA) and BP neural network. A WPA-BP hybrid neural network algorithm is the integration of WPA to optimize the weight and threshold of the BP neural network. Training samples for the BP neural network are derived from RSSI signal strength and tag coordinates measured by the RFID reader, while the WPA algorithm optimizes the threshold and weight values of the neural network, resulting in a WPA-BP neural network model algorithm. Compared with experimental results of indoor localization based on BP algorithm and WPA-BP algorithm, the results using WPA-BP hybrid algorithm reduces errors in RFID indoor positioning, mitigates the impact of environmental factors, and enhances overall performance based on RSSI.
Kenwords : indoor positioning ; neural network ; wolf pack algorithm; Radio Frequency Identification
Characterization of Qu-aroma of Medium-High Temperature Daqu from Different Production Areas Using Sensory Evaluation, E-nose, and GC-MS/O Analysis
Authors: Jie Deng , Zheng Jia , Li Xing , Huang Zhiguo , Huang Dan , Ye Guangbin , Luo Huibo 
Published: December 2024

Abstract

Qu-aroma is a critical quality indicator for medium-high temperature Daqu (MT-Daqu). Due to the differences in regional and environmental conditions, these differences are likely to cause variations in the Qu-aroma of MT-Daqu. Despite this, comprehensive research on the variations in Qu-aroma across different regions has been lacking. This study aims to address this gap to analyze the differences in Qu-aroma characteristics of MT-Daqu from seven distinct production areas. Sensory analysis identified seven broad aroma categories and 25 specific aromas characterizing the Qu-aroma of MT-Daqu samples. Chen aroma and roasted aroma were notably more prevalent in MT-Daqu samples from Sichuan compared to those from other regions (P < 0.05). In total, 123 volatile compounds were detected in MT-Daqu, with 46 classified as aroma-active compounds. Among these, 21 aroma-active compounds were identified as markers distinguishing Sichuan MT-Daqu from those produced in non-Sichuan regions, showing significant differences in their concentrations (P < 0.05). Additionally, six major aroma-active compounds were found to significantly contribute to the aroma differences between Sichuan and non-Sichuan MT-Daqu. This study delineates the distinct Qu-aroma characteristics of MT-Daqu from various SAB production areas. The insights gained from this research offer valuable guidance for optimizing flavor profiles in MT-Daqu production.
Mixed infection with Colletotrichum species and Alternaria alternata causes fruit rot on processing tomato fruits
Authors: Hariya Atsuki , Maeda Kazuya , Osaka Masaaki , Iwao Eishin , Imano Sayaka , Asano Satoshi , Kubo Yasuyuki , Iida Yuichiro 
Published: December 2024

Abstract

Severe fruit rot was observed on ripe processing tomatoes in an open field in Japan. Round, sunken lesions formed on the fruits, with numerous black conidia in the center; the rot eventually expanded, sometimes over the entire fruit. Fungal isolates from lesions on the fruits were identified as Colletotrichum cliviicola, C. fioriniae and Alternaria alternata based on phylogenetic analysis. Isolates of C. cliviicola and C. fioriniae caused sunken lesions with ochre to blackish colonies on ripe but not unripe tomatoes. The A. alternata isolates also caused sunken lesions with white to blackish colonies only on ripe fruits. Thus, C. cliviicola, C. fioriniae, and A. alternata caused the fruit rot on processing tomatoes. Sequential inoculation of processing tomato fruits with C. cliviicola and A. alternata also caused symptoms similar to those in the field, suggesting that a mixed infections can lead to this severe fruit rot.
Inclusion complexes of serotonin and dopamine with a dioxa-pentaaza-cyclophane
Authors: Moreno-Pérez Teresita , Valencia Ángel U. Orozco , Soberanes Yedith , Sotelo-Mundo Rogerio R. , Inoue Motomichi , Santacruz Hisila , Navarro Rosa E. 
Published: December 2024

Abstract

In attempt to find new type of artificial receptors towards neurotransmitters, NMR studies were carried out on the supramolecular complexation of serotonin and dopamine with a dioxa-pentaaza-cyclophane derived from diethylenetriaminepentaacetic acid (known as DTPA); at the pH 7.2, the macrocycle composed of three phenylene groups is negatively charged with three anionic -CH2CO2− arms, whereas the aromatic neurotransmitters carry a cationic -NH3+ group. Aromatic protons in the cyclophane exhibit up-field shifts due to the ring current effect of the neurotransmitters in NMR titration; the through-space interaction is confirmed by NOESY (Nuclear Overhauser Enhancement and Exchange Spectroscopy). Geometry optimization shows that the macrocycle can encapsulate either neurotransmitter molecule to form a 1:1-inclusion complex in which electrostatic and hydrogen-bonding interaction operate between the functional groups of the component molecules. The through-space interaction is stronger for serotonin because of its better fitness to the macrocyclic cavity. The thermodynamic stabilities of the complexes are about 20 M− 1 in D2O, and are very slightly decreased in the coexistence of electrolytes. The complexation is promoted by the electrostatic and hydrogen bonds. The resulting ion-pair is stabilized by the successive encapsulation, which protects the weak bonds against the electrostatic field of the electrolyte. The combination of multiple types of interacting sites may be crucial in the design of receptors that can function under isotonic conditions.
Nano-Emulsification of PTX and BEZ235 inhibit colon cancer growth
Authors: Zhu Xingyao , Zhang Ruiqi , Liu Yuhua , Yang Caiyun , Ding Qi , Gu Wenyi , Zou Hong 
Published: December 2024

Abstract

As the most common malignant tumor, colorectal cancer is a serious threat to people's health, especially the problem of drug resistance, is a huge challenge. In previous studies, we have found synergistic anti-colon cancer effects with the combination of paclitaxel and BEZ235, especially for drug-resistant colorectal cancer with excellent anti-tumor effects. Therefore, this study aims to investigate the preparation of Nano-Emulsification of paclitaxel and BEZ235 (NEs-PTX-BEZ235), and to explore the potential key parameters of its clinical transformation. To provide a new therapeutic strategy for colorectal cancer, especially for drug-resistant colorectal cancer. The nanomaterials were prepared by low energy self-emulsification method, and analyzed by Malvern laser particle size analyzer. Cell drug uptake was observed under fluorescence microscope. CCK8, Western blot and flow cytometry were used to compare the anti-cancer effects and mechanisms of different experimental groups on ordinary and drug-resistant colon cancer cells. Human colon cancer primary cells were extracted to verify the anti-tumor effect of drugs. Finally, we found that NEs-PTX-BEZ235 significantly killed colon cancer cells, especially drug-resistant cells, and better than Nab-PTX. It may play a synergistic role in reducing drug resistance, inhibiting tumor stemness and inducing apoptosis of colon cancer cells by inhibiting drug resistance proteins.
Scaling up medications for opioid use disorder in Kentucky: Qualitative perspectives of treatment organizations
Authors: Knudsen Hannah K. , Andrews-Higgins Shaquita , Back-Haddix Sandra , Lofwall Michelle R. , Fanucchi Laura , Walsh Sharon L. 
Published: December 2024

Abstract

Background
Underutilization of medications for opioid use disorder (MOUD), which reflects the limited number of patients initiating treatment and being retained in treatment, remains a persistent barrier to addressing the opioid epidemic. Using an adapted PRISM (Practical, Robust Implementation and Sustainability Model) framework, this study describes multi-level barriers and facilitators to expanding MOUD as part of the HEALing (Helping to End Addiction Long-term®) Communities Study in Kentucky (HCS-KY).
Methods
Cross-sectional small group and individual semi-structured interviews were conducted with 60 employees representing 30 MOUD agencies in eight Kentucky counties from December 2022 to June 2023. A deductive-dominant approach to interviewing, with all interviews recorded and transcribed. Using a codebook informed by the adapted PRISM framework, a directed consensus-based approach to coding and thematic analysis was used.
Results
Although some agencies had a fairly static number of patients, most described recent experiences with modest growth in MOUD census and the ability to provide same day/next day MOUD. Multi-level factors, including organizational, patient-level, and community characteristics and perspectives, were perceived to impact MOUD census. Organizational characteristics impacting growth included the physical space of the clinic and staffing. Organizational policies in some agencies constrained treatment retention, while other agencies implemented innovations to better meet patients’ needs. Patients often encountered numerous challenges to treatment initiation and retention, including limited access to transportation, technology, safe and stable housing, and childcare. These patient-level barriers often reflected community characteristics, while community stigma also impeded MOUD growth.
Conclusions
These qualitative data revealed that some degree of growth in MOUD has occurred, but multi-level barriers are impeding further increases in treatment initiation and retention. Some barriers likely require policy changes related to financing and regulation, while other barriers require community-level efforts to decrease stigma and greater community investment in infrastructure, such as transportation and housing.
Trial registration
ClinicalTrials.gov, NCT04111939. Registered 30 September 2019,
Exploring the Relationship of Glucose and Keloid: a Comprehensive Mendelian Randomization Study
Authors: Cao Jiaojiao , Hu Chenglu 
Published: December 2024

Abstract

Keloid, a prevalent disorder of dermal fibroproliferation, manifests as benign tumors with massive proliferation of fibroblasts and overabundance of extracellular matrix. The limited efficacy of existing keloid treatments underscores the critical need for novel therapeutic approaches and strategies. Alterations in glucose metabolism of keloid fibroblasts correlate with keloid progression. Mendelian randomization (MR) analysis is a potent and robust epidemiological statistical method that employs genetic variants as instrumental variables to assess causality. Nonetheless, the exact nature of the causal relationship between glucose and keloid is yet to be determined. In this study, we first used GEO data for differential expression analysis in keloid and normal tissues, GO and KEGG pathways enrichment analyses, and gene screening and PPI network construction. Subsequently, We performed MR analysis of glucose and keloid, and sensitivity analysis with MR analysis of key differential genes. Finally, single-cell analysis was used for cell type annotation, intercellular communication analysis, pseudotime analysis, and GSEA analysis. The results showed that different glucose levels displayed protective effects in keloid. In addition, there was a causal relationship between ENSG00000136111 (gene TBC1D4) and keloid and it manifested as a protective factor for keloid. Higher TBC1D4 expression favored the differentiation of normal endothelial cells and NK cells. Therefore, our MR analysis emphasized a robust causal relationship between glucose and keloid, and indicated glucose as a dominant protective factor for keloid, theoretically providing evidence for keloid prevention and treatment.
Dense-Stream YOLOv8n: A Lightweight Model Method for Real-Time Crowd Monitoring in Smart Libraries
Authors: Chen Zini , Xie Xuming , Qiu Taorong , Yao Yuelei 
Published: December 2024

Abstract

Crowd monitoring in the context of smart libraries is of great significance for resource optimization and service improvement. Addressing the challenges of insufficient accuracy and real-time performance in crowd detection under high-density and side-view scenarios in dynamic library environments, this paper proposes a crowd detection method based on an improved YOLOv8n model. First, side-view crowd videos from different time periods in the library were collected, segmented into images, and manually annotated to generate a high-quality training dataset. Then, a lightweight convolutional data augmentation module called DensityNet was designed to enhance the model's feature extraction capabilities in crowded occlusion scenes. Subsequently, model pruning and knowledge distillation techniques were combined to reduce model complexity and improve detection real-time performance, adapting it to the computational requirements of edge devices. Finally, a region detection algorithm was designed to better accommodate the needs of crowd monitoring in high-density and constrained-view dynamic environments by extending the detection trigger time, thereby providing an accurate and contactless solution for people flow monitoring in smart libraries. Experimental results show that the improved YOLOv8n model achieves an average precision (mAP@0.5) of 0.99 in high-density scenarios, close to the original model's 0.991, while achieving 0.861 in mAP@0.5:0.95, an increase of 0.014 over the model before pruning; in terms of real-time performance, the frame rate (FPS) significantly increased to 254, with computational costs reduced to 4.0 GFLOP and the number of parameters decreased to 2.04M, meeting the real-time detection needs of peak crowd environments in smart libraries. This study addresses the unique people flow monitoring requirements of smart libraries by proposing an efficient and accurate solution, which not only optimizes resource and service management but also provides new technical support for the intelligent management of other domains.
A new C-eigenvalue localization interval for piezoelectric-type tensors
Authors: Xu Yangyang , He Guinan , Shao Licai , Chen Zimo 
Published: December 2024

Abstract

Given a piezoelectric-type tensor, its C-eigenvalues which play an important role in piezoelectric effect and converse piezoelectric effect of physics are always real and existed. In this paper, a new C-eigenvalue localization interval for piezoelectric-type tensors is presented. The newly proposed C-eigenvalue localization interval for piezoelectric-type tensors improves the previous one in [C-eigenvalue inclusion theorems for piezoelectric-type tensors, Appl. Math. Lett., 89(2019) 41-49]. To further examine the effectiveness and validity of the main result, some numerical experiments are considered by comparing with some previously known results.
AMS subject classifications: 15A69, 15A18, 15A42.
Power Control Scheme of Reconfigurable Intelligent Surface-Assisted Wireless Communication System Based on Millimeter-Wave Radar
Authors: Wenyu Luo , Annan Xuan , Tianze Yan , Xia Shao 
Published: December 2024

Abstract

To address the problem of excessive communication system overhead caused by high path loss, low scattering, and frequent switching of high-band communication in complex dynamic wireless environments, a reconfigurable intelligent surface (RIS)-assisted wireless communication system power control scheme based on frequency-modulated continuous-wave millimeter-wave radar (FMCW) is proposed. This paper proposes a power optimization scheme that senses dynamic users and characterizes dynamic environments.The FMCW radar is used to perceive the user and obtains dynamic position information about the user. To maximize the expectation of the signal-to-noise ratio (SNR) of the communication, the upper bound of the system interruption probability is obtained by analysing the effect of the user's location on the system reliability. Moreover, considering the influence of the multipath effect on the system gain, a geometric channel model is established to better reflect the dynamic environment under the multipath effect. Subsequently, while conforming to the constraints of the communication system, the power optimization method based on the binary search algorithm was adopted. Finally, the influence of the FMCW radar perception error on the power control results was analysed, and the error value of the power required for transmission by the base station was 0.4-0.5 dB within the error range. The simulation and analysis results show that the power required for base station transmission obtained using the proposed scheme is approximately 4 dB, which can effectively reduce the power required for system base station transmission.
The Impact of Health-Caregivers Emotional Nurturance on Cognitive Development in Preschoolers: A Nationwide Public Health Cross-Sectional Study
Authors: Sharma Prakash , Adamopoulos Ioannis , Syrou Niki , Budhathoki Chitra Bahadur , Thapa Pramila 
Published: December 2024

Abstract

Background: Early childhood cognitive development is influenced by a range of socio-economic, emotional, and environmental factors. This study investigates the association between emotional nurturance and cognitive development in preschool-aged children in Western Tarai of Nepal.
Methods: A cross-sectional study was conducted with 391 preschoolers from diverse socio-economic backgrounds. Cognitive outcomes were assessed, and socio-economic data, including Health-caregiver education, occupation, caste/ethnicity, and family structure, were analyzed alongside emotional nurturance scores. Multivariate linear regression models were used to assess the associations, adjusting for relevant covariates.
Results: Age and certain socio-economic factors were significantly associated with cognitive outcomes. Children aged 36–48 months showed notably higher cognitive scores compared to older age groups, and children from joint families scored higher than those from nuclear families. Additionally, children from disadvantaged caste backgrounds (Dalit and Janajati) demonstrated lower cognitive outcomes compared to those from advantaged castes, highlighting ongoing disparities. Emotional nurturance was positively but not significantly associated with cognitive development after adjustments.
Conclusion: Socio-economic disparities, particularly caste and family structure, play a critical role in shaping cognitive outcomes among young children in Nepal. The findings underscore the need for policies targeting socio-economic inequities to promote equitable cognitive development, and Population preventive Public Health especially in pre-school children. Supportive interventions focusing on joint family systems and educational opportunities for mothers may further enhance cognitive outcomes in rural settings.
Highly efficient cerium metal organic frameworks (Ce-UiO-66) and its inorganic hybrids nanocomposite as novel heterogenous catalyst for Knoevenagel condensation reaction
Authors: BOYNITO DINGETEGNA GODANA , TADDESSE ABI M. , G. Neelaiah Babu 
Published: December 2024

Abstract

Heterogeneous catalysis is a prominent application of metal-organic frameworks (MOFs), which have garnered significant interest from researchers over the past two decades due to their unique hybrid organic/inorganic nature. This study aimed to synthesize Ce-UiO-66 and its inorganic hybrids (CdS/Ce-UiO-66/Ag3PO4) and to assess their effectiveness as heterogeneous catalysts in the Knoevenagel condensation reaction. All materials were synthesized through hydrothermal methods and characterized using X-ray powder diffraction (XRD) and scanning electron microscopy (SEM). The organic components were analyzed with 1H-NMR and 13C-NMR spectroscopy. The catalytic performance of Ce-UiO-66 and its inorganic hybrids was evaluated under optimized conditions for various aldehyde substrates and malononitrile in aqueous media, focusing on reaction time, catalytic activity, and yield. The results showed that the yield of the target product followed this trend: T1 > CdS/Ce-UiO-66 > Ce-UiO-66. The catalytic system was also tested with various aromatic aldehydes, achieving over 90% conversion at room temperature. Additionally, the catalyst maintained its catalytic efficiency after being reused more than three times. Overall, this research highlights the synthesis of Ce-MOF and its inorganic hybrids and their catalytic performance in the Knoevenagel condensation reaction.
ИНТЕЛЛЕКТУАЛЬНОЕ ОСВОЕНИЕ КАВКАЗА В КОНТЕКСТЕ ОРИЕНТАЛИСТСКОГО НАРРАТИВА ПЕРИОДИЧЕСКОЙ ПЕЧАТИ 1820–1840 ГГ.
Authors: Ткаченко Д.С. 
Published: December 2024

В статье анализируется ориенталистский дискурс нарратива, определявший логику и смыслы составления военно-политических и этнокультурных описаний событий на Кавказе и жителей региона. Источниками анализа стали публикации современников в центральных и региональных периодических изданиях первой половины XIX в. Периодические издания представляли читателям знания о своем регионе и транслировали четкие политические и культурные установки, легитимировали и усиливали сложившиеся отношения как внутри региональных сообществ, так и их с центральной имперской администрацией. Авторов статей различного содержания и политических взглядов, в описаниях народов региона объединяло использование ряда постулатов, терминов и методологических подходов, сложившихся в европейской колониальной практике XVIII–XIX вв. при описаниях Восточных культур.
The paper focuses on the study of Orientalist discourse in narrative, which determined the logic and meaning of compiling military-political and ethno-cultural descriptions of the Caucasus and its inhabitants. The sources of the analysis were the publications in central and regional periodicals of the first half of the 19th c. They provided readers with not only knowledge about their region, but also conveyed clear political and cultural guidelines, legitimized and strengthened the existing relationships both within regional communities and with the central imperial administration. The authors were united by the use of a number of postulates, terms and methodological approaches developed in European colonial practice of the 18th–19thc. in descriptions of Oriental cultures.