bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge, attitudes and practices towards viral haemorrhagic fevers amongst healthcare workers in urban and rural public healthcare facilities in the N’zérékoré Prefecture, Guinea: a cross-sectional study
Authors: Raab Manuel , Pfadenhauer Lisa M. , Millimouno Tamba Jacques , Hoelscher Michael , Froeschl Guenter 
Published: December 2019

Abstract
Introduction: The 2013-2016 Ebola epidemic in West Africa began in Guinea’s Forest region, a region now considered to be at high risk for future epidemics of viral haemorrhagic fevers. Good knowledge, attitudes and practices towards viral haemorrhagic fevers amongst healthcare workers in such regions are a central pillar of infection prevention and control. To inform future training in infection prevention and control, this study assesses the knowledge, attitudes and practices (KAP) towards viral haemorrhagic fevers amongst healthcare workers in public healthcare facilities in the most populated prefecture in Forest Guinea, and compares results from urban and rural areas. Methods: In June and July 2019, we interviewed 102 healthcare workers in the main urban and rural public healthcare facilities in the N’zérékoré prefecture in Forest Guinea. We used an interviewer-administered questionnaire adapted from validated KAP surveys. Results: The great majority of respondents demonstrated good knowledge and favourable attitudes towards viral haemorrhagic fevers. However, respondents reported considerable gaps in preventive practices, a shortage of protective medical equipment used in everyday clinical work in both urban and rural healthcare facilities and a lack of training in infection control and prevention, especially in rural healthcare facilities. Conclusions: Three years after the end of the Ebola epidemic, our findings suggest that public healthcare facilities in the N’zérékoré prefecture in Forest Guinea still lack essential protective equipment and adequate training in viral haemorrhagic fever infection prevention and control. Especially rural areas seem to be affected of this lack. To minimize the risk of future viral haemorrhagic fever epidemics and other outbreaks of infectious diseases in the region, current efforts to strengthen the public healthcare system in Guinea should supply enough protective medical equipment and ensure that regular IPC trainings have a positive impact and that preventive practices are followed in everyday clinical work.
The epidemiology of heart failure in the general Australian community - Study of Heart failure in the Australian Primary carE setting (SHAPE): methods
Authors: Parsons Richard Whaddon , Liew Danny , Neville A Munro , Audehm Ralph G , Haikerwal Deepak , Piazza Peter , Lim Kevin , Sindone Andrew P 
Published: December 2019

Abstract
Background: There is a paucity of information on the epidemiology of heart failure (HF) in Australia. The Study of Heart failure in the Australian Primary carE setting (SHAPE) study aims to estimate the prevalence and annual incidence of HF in the general Australian community and to describe the demographic and key clinical profile of Australians with HF. Methods: We undertook a retrospective cohort study based on analysis of non-identifiable medical records of adult patients cared for at 43 general practices between 1 July 2013 and 30 June 2018. Data were extracted from coded (diagnosis, pathology and prescription fields) and uncoded fields (clinical notes) in the medical records. The latter searches of free text looked for common synonyms relevant to HF. The population was stratified into three groups based on a hierarchy of selection criteria: (1) definite HF, (2) probable HF and (3) possible HF. The prevalence and annual incidence of HF were calculated, along with 95% confidence intervals. Results: The practices provided care to 2.3 million individual patients over the five-year study period, of whom 1.93 million were aged 18 years and above. Of these patients 16,930 were classified as having ‘definite HF’, 4873 as having ‘probable HF’ and 36,517 as having ‘possible HF’. A further 40,992 were identified as having an aetiological condition associated with HF. These estimates accord with findings in similar populations from other countries. Among ‘active patients’ (regular attenders of a practice), the crude prevalence of HF was 1.813% (95%CI:1.79–1.84%), and the age-standardised prevalence was 2.199% (95%CI:2.168-2.23%). The annual incidence was 0.291% (95%CI:0.286–0.296%), and the age-standardised annual incidence was 0.348% (95%CI:0.342–0.354%). The estimates of prevalence and incidence suggest that almost 420,000 people were living with HF in Australia in 2017, and over 66,000 new cases of HF occurred that year. Conclusions: This novel approach to undertaking retrospective research of primary care data successfully analysed a combination of coded and uncoded data from the electronic medical records of patients routinely managed in the GP setting. SHAPE is the first real-world study of the epidemiology of HF in the general Australian community setting.
Work related low back pain and associated factors among hairdressers in Mekelle, Tigray, Ethiopia; cross-sectional study.
Authors: Tsegay Gebrerufael Solomon , Gebremeskel Berihu Fisseha , Gezahegn Selam Desalegn , Teklemichael Desalegn Massa 
Published: December 2019

Abstract
Background Low back pain is one of the most prevalent musculoskeletal conditions and the most common cause of disability. Hairdressers are one of the high-risk professionals for work-related musculoskeletal disorders like low back pain. However, studies on the prevalence and associated factors of low back pain among hairdressers are scarce. The objective of the current study is to assess the magnitude and associated factors of work related low back pain among hairdressers working in female beauty salons.Method An institutional-based cross-sectional study was employed from January 05 up to February 28, 2018. The sample (n=344) hairdressers were selected randomly from all-female beauty salons of Mekelle city. A structured questionnaire adapted from a standardized Nordic questionnaire and other similar studies was used. Binary logistic regression analysis was performed to identify factors associated with low back pain. The Adjusted Odds Ratio (AOR) with a 95% Confidence Interval (CI) was estimated to show the strength of association. A p-value of < 0.05 was used to declare statistical significance.Result A total of 314 hairdressers participated, with a 91.3% response rate. The study found that the self-reported 12 months prevalence of work related low back pain was (47.5%) with 95%CI (41.8- 53.1). Awkward way working posture [AOR: 2.6, 95%CI (1.41- 4.62)], working greater than 4 days in a week [AOR: 7.98, 95%CI (2.54-25.09], hair washing job category [AOR: 4.35, 95%CI (1.87-10.12)], having adjustable washing basin [AOR: 0.30, 95%CI (0.151-0.587)] and job stress [AOR: 2.75, 95%CI (1.61-4.72)] were factors that shows a statically significant association with low back pain.Conclusion This study found that work-related low back pain is a major health problem among hairdressers.Working in awkward postures, more working days per week, hair washing job category and job stress show strong association with work related low back pain, whereas using adjustable height washing basin has a protective effect for low back pain. Responsible bodies need to give attention to prevent low back pain among hairdressers by giving on job training related to comfortable working posture and utilization of ergonomically designed tools.
Factors contributing to health care utilization and health care costs in the long term after stroke. Secondary results from the Life After Stroke (LAST) study, a pragmatic randomized controlled trial
Authors: Døhl Øystein , Halsteinli Vidar , Askim Torun , Gunnes Mari , Hansen Hege Ihle , Indredavik Bent , Langhammer Birgitta , Phan Ailan , Magnussen Jon 
Published: December 2019

Abstract
Background The result from the Life After Stroke (LAST) study showed that an 18-month follow up program as part of the primary health care, did not improve maintenance of motor function for stroke survivors. In this study we evaluated whether the follow-up program could lead to a reduction in the use of health care compared to standard care. Furthermore, we analyse to what extent differences in health care costs for stroke patients could be explained by individual need factors (such as physical disability, cognitive impairment, age, gender and marital status), and we tested whether a generic health related quality of life (HRQoL) is able to predict the utilisation of health care services for patients post-stroke as well as more disease specific indexes. Methods The Last study was a multicentre, pragmatic, single-blinded, randomized controlled trial. Adults (age ≥18 years) with first-ever or recurrent stroke, community dwelling, with modified Rankin Scale <5. The study included 380 persons recruited 10 to 16 weeks post-stroke, randomly assigned to individualized coaching for 18 months (n=186) or standard care (n=194). Individual need was measured by the Motor assessment scale (MAS), Barthel Index, Hospital Anxiety and Depression Scale (HADS), modified Rankin Scale (mRS) and Gait speed. HRQoL was measured by EQ-5D-5L. Health care costs were estimated for each person based on individual information of health care use. Multivariate regression analysis was used to analyse cost differences between the groups and the relationship between individual costs and determinants of health care utilisation. Results There were higher total costs in the intervention group. MAS, Gait speed, HADS and mRS were significant identifiers of costs post-stroke, as was EQ-5D-5L. Conclusion Long term, regular individualized coaching did not reduce health care costs compared to standard care. We found that MAS, Gait speed, HADS and mRS were significant predictors for future health care use. The generic EQ-5D-5L performed equally well as the more detailed battery of outcome measures, suggesting that HRQoL measures may be a simple and efficient way of identifying patients in need of health care after stroke and targeting groups for interventions. Clinical Trial Registration: https://www.clinicaltrials.gov NCT01467206.
Microbial community dynamics in the recirculating nutrient solution of tomato plug seedlings cultivated under ebb-and-flow system
Authors: Dong Chun-Juan , Li Qian , Wang Ling-Ling , Shang Qing-Mao 
Published: December 2019

Abstract
Background: The ebb-and-flow system has ability to recirculate water and nutrients, and offers a good method to control nutrient leaching from greenhouses into the environment. However, the potential for the rapid spread of bacterial and fungal pathogens is the main hindrance for its adoption in vegetable seedlings production. Natural microflora has often shown a certain ability to suppress diseases.Results: Here, through 16S rRNA- and ITS1-targeted Illumina sequencing, the dynamic changes in bacterial and fungal communities in the recirculating nutrient solution were characterized for tomato plug seedlings cultivated in an ebb-and-flow system in summer and winter. Both bacterial number and microbial diversity in the nutrient solution increased with recirculating irrigation, and these changes differed between summer and winter. Pseudomonas was among the most predominant bacterial genera in the nutrient solution; its relative abundance gradually increased with recycling in summer but decreased dramatically in winter. In summer, the predominant bacteria also included Comamonas and Sediminibacterium , whose relative abundances in the nutrient solution decreased and increased, respectively. In winter, the nutrient solution was also colonized by Sphingomonas , predominantly at the late stage of irrigation. Among fungi, Amanita and Trichoderma were predominant in both summer and winter. Amanita gradually increased in summer but decreased rapidly after the first irrigation cycle in winter, whereas Trichoderma accumulated rapidly at the late stage of irrigation in both summer and winter. Alternaria and Fusarium were predominant in the nutrient solution only in summer, with the former decreased and the latter increased with recirculating irrigation. Moreover, Pseudomonas mediterranea , a potentially pathogenic bacterium, and Fusarium oxysporum , a fungal pathogen were present predominantly in winter and summer, respectively. Some potentially beneficial microbes functioning in plant-growth promotion and water self-purification, such as Sphingobium xenophagum , Trichoderma harzianum , and T. virens , were identified to be increased in the recirculating nutrient solution.Conclusions: The present data elucidate the bacterial and fungal dynamics in an ebb-and-flow system and provide useful information for pathogen control during tomato seedling production.
Adaptive Information Assimilation using Convolutional Neural Network for Forecast of Breast Cancer from Electronic Health Records
Authors: J Senthil Kumar Kumar , K Kamala Devi , J Raja Sekar 
Published: December 2019

Abstract
Purpose Data acquired from cancer based Electronic Health Records (EHRs) shows key statistics on cancer affected persons. To estimate the impact of the cancer on those persons, we need to extract vital information from those pathology health records. It is an exhaustive procedure to carry out because of large volume of records and data acquired for a continuous period of time.Methods This research portrays, the investigation of convolutional neural network (CNN) and Support Vector Machine (SVM) techniques for extracting topographic codes from the pathology reports of breast cancer. Investigations are carried out using conventional frequency vector space method and the deep learning techniques such as CNN. The learning experience of those algorithms were absorbed on a set of 730 pathology reports.Results We perceived that the CNN technique reliably outperformed the conventional frequency vector methods. It is also observed that it causes the micro and macro average performance to increase up to 0.119, and 0.101, while considering the populated class labels for the CNN model. Unambiguously, the top performing CNN approach attained a micro-F score of 0.821 over the considered topography codes.Conclusion These promising outcomes reveals the prospective of deep learning approaches, particularly CNN for estimating the impact of the cancer from the pathology reports compared to conventional SVM approach. More advanced and accurate approaches to effectively improve the accuracy in information extraction are needed.
Utility and safety of cobalt chromium needles for endobronchial ultrasound-guided transbronchial needle aspiration: a retrospective single-center study
Authors: Uchimura Keigo , Yamasaki Kei , Hara Sachika , Tachiwada Takashi , Kawanami Toshinori , Kisohara Akira , Yatera Kazuhiro 
Published: December 2019

Abstract
Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a standard method for obtaining specimens of mediastinal and hilar lesions, and several types of needle of various sizes and materials are available. This study aimed to compare the utility and safety of two needles, cobalt chromium (CC) and stainless steel (SS), for EBUS-TBNA.
Methods: This retrospective study included data of patients who underwent EBUS-TBNA with a 22-gauge needle made from either SS (38 patients, 121 punctures) or CC (39 patients, 145 punctures), and procedure time, histological data, complication rates were compared.
Results: There were no significant differences between the groups in the baseline characteristics of the patients or lesions or in the complication rates. Although diagnostic yields in each patient who underwent EBUS-TBNA with the two needle types were similar, significantly shorter procedure time (22 min vs. 26 min, p = 0.007), diagnostic histologic sampling yield in each sample (71.0% vs. 58.7%, p = 0.039), fewer samples with cartilage alone (1.4% vs. 6.6%, p = 0.047) and fewer samples containing cartilage (7.6% vs. 16.5%, p = 0.034) were seen in the CC group compared with that in SS needle group.
Conclusion: Compared with SS needles, CC needle for EBUS-TBNA showed significant shorter procedure time and higher ratio of getting diagnostic histological specimens in each sample. This might be because of better ability of CC needle to puncture through the trachea and bronchial cartilage to get appropriate lymph node sampling.
Computed tomography-guided cutting needle biopsy for lung nodules: when the biopsy-based benign results are real benign
Authors: Hui Hui , Yin Hai-Tao , Zhou Yun , Xie Xiao-Mei , Wang-Yang Yu-Fan , Li Xing , Wang Tao 
Published: December 2019

Abstract
Background: Computed tomography (CT)-guided cutting needle biopsy (CNB) has been widely used for the diagnosis of lung nodules (LNs). The false-negative rate of CT-guided lung biopsy is reported to be up to 16%. The aim of this study was to determine the predictors of true-negative results in LNs with CNB-based benign results.
Methods: From January 2011 to December 2015, 96 patients with CNB-based non-specific benign results were included in this study as the training group to detect predictors of true-negative results. From January 2016 to December 2018, an additional 57 patients were included as a validation group to test the reliability of the predictors.
Results: In the training group, a total of 96 patients underwent CT-guided CNB for 96 LNs. The CNB-based results were true-negatives for 82 LNs and false-negatives for 14 LNs. The negative predictive value of the CNB-based benign results was 85.4% (82/96). Univariate and multivariate logistic regression analyses revealed that CNB-based chronic inflammation with fibroplasias (P = 0.013, hazard ratio = 0.110, 95% confidential interval = 0.019–0.625) was the independent predictor of true-negative results. The area under the receiver operator characteristic (ROC) curve was 0.697 (P = 0.019). In the validation group, biopsy results for 47 patients were true-negative and 10 were false-negative. When the predictor was used on the validation group, the area under the ROC curve was 0.759 (P = 0.011).
Conclusions: Most of the CNB-based benign results were true-negatives, and CNB-based chronic inflammation with fibroplasias could be considered a predictor of true-negative results.
Impact of GTF2H1 and RAD54L2 gene polymorphisms on the non-small cell lung cancer with Platinum chemotherapy in high altitude areas
Authors: Li Miao , Chen Rong , Ji Baoyan , Fan Chunmei , Wang Guanying , Yue Chenli , Jin Guoquan 
Published: December 2019

Abstract
Background Repair pathway genes are closely related to the sensitivity of tumor patients to drugs. It is particularly important to study the correlation between non-small cell lung cancer (NSCLC) and DNA repair gene (GTF2H1 and RAD54L2) in high altitude areas.Materials and methods Four SNPs on RAD54L2 and five SNPs on GTF2H1 were genotyped via the Agena MassARRAY in 506 age-and gender-matched patients with NSCLC and 510 healthy controls. The influence of GTF2H1 and RAD54L2 on lung cancer was assessed by logistic regression analysis. The effects of polymorphisms of these two genes on the efficacy and side effects of NSCLC patients with platinum-based chemotherapy were further evaluated.Results RAD54L2 rs9864693 GC heterozygote genotype was increased the risk of NSCLC (OR = 1.33, 95%CI: 1.01 – 1.77, p = 0.045). Stratified analysis found that GTF2H1 rs4150667 promoted the risk of lung cancer in individuals younger than 59 years group (OR = 1.32, 95%CI: 1.00 – 1.75, p = 0.048). However, the individuals with GTF2H1 rs3802967 CT-TT reduced the risk of the lung squamous cell carcinoma by 32% (OR = 0.68, 95%CI: 0.46 – 0.99, p = 0.045). The patients with GTF2H1 rs3802967 TT genotypes showed a significantly higher curative effect (OR = 2.65, 95%CI: 1.14 - 6.15, p = 0.023); patients with GTF2H1 rs3802967 TT genotypes showed a significantly lower risk of side effects (OR = 0.32, 95%CI: 0.10 - 0.98, p = 0.047).Conclusion Our study indicated that RAD54L2 and GTF2H1 gene was associated with NSCLC susceptibility.
Representatividade do Mercado de hospedagem de Campo Grande (MS) nos canais de distribuição acessados pelas tecnologias de informação e comunicação (TICS)
Authors: Belino Bonfim Izac Oliveira , Velasquez Guilherme Garcia , Leal Ana Beatriz de Almeida Carneiro 
Published: December 2019

Os meios de hospedagem utilizam diversas estratégias de distribuição do seu produto. Entre as opções encontram-se disponíveis os canais de distribuição diretos e indiretos. A captação e a fidelização de consumidores são mensuradas através das inovações tecnológicas que mensuram a competividade da organização. Entre os canais de distribuição destacam-se as tecnologias de informação e comunicação [TICs], consideradas importantes ferramentas de uso estratégico para se aumentar as vendas do produto hoteleiro. Diante deste contexto, o presente estudo teve como objetivo mensurar os dados quantitativos de distribuição e inovação nos Meios de Hospedagem [MH] da Cidade de Campo Grande, Estado de Mato Grosso do Sul. Para se chegar aos resultados finais utilizou-se de uma metodologia quali-quantitativa de análise de dados do CADASTUR objetivando identificar o número total de empreendimentos que estão legalizados de acordo com a Lei Geral do Turismo 11.771/2008. Buscou-se posteriormente identificar por meio das On Line Travel Agencies [OTAs]: Booking, Hotel Urbano, Hotels, Decolar e a plataforma de reservas AIRBNB, quais são as mais contratadas pelo mercado hoteleiro. Por meio dos sites dos Hotéis, analisaram-se quais empreendimentos possuem Motor de Reservas como uma ferramenta de reservas on line. Destaca-se como principais resultados a existência de um número significativo de empreendimentos na cidade que não são oficialmente cadastrados no Cadastur (Mtur). Ainda, apontou-se a existência de vendas de hospedagem por meio de plataformas como AIRBNB, capazes de colocar a hotelaria local em posição de vulnerabilidade e/ou como uma estratégia de canal de vendas para os hotéis que não conseguem investir em tecnologia, demonstrando, ao menos tempo a urgência por definição de estratégias competitivas e inovação para o mercado hoteleiro de Campo Grande/MS.
Palavras-chave: Mercado Hoteleiro. Mato Grosso do Sul. Representatividade. Tecnologias de informação.
A Avaliação da Aprendizagem na Organização de Eventos: um estudo de caso
Authors: Sales Aguiar Eveline Porto , Carvalho de Melo Stella Maria , Rodrigues Gadelha Conceição Nubenia 
Published: December 2019

A realização de eventos, seja qual for a sua tipologia demanda tempo, preparo e sobretudo conhecimento teórico, que podem ser adquiridos em um ambiente de educação. Assim, esta pesquisa buscou unir verificar como os alunos do Curso de Extensão “Festas & Recepções: a arte de servir à mesa” do IFCE Aracati-CE avaliaram o aprendizado com a teoria e prática de organização de eventos. O curso atendeu a 21 alunos, todos da comunidade externa e sua avaliação final teve como atividade a organização de um evento prático, organizado pelos próprios discentes. Trata-se uma pesquisa bibliográfica e de levantamento de campo, focada em um estudo de caso, com abordagem quantitativa. Para a coleta de dados, utilizou-se um questionário com os alunos que organizaram o evento prático. As perguntas investigaram o tempo destinado para as aulas teóricas e práticas; metodologia de ensino; tempo para planejamento do evento; entre outros. Constatou-se que os alunos ficaram muito satisfeitos com o curso, mostrando que suas habilidades na organização de eventos foram aprimoradas com essa capacitação. Assim, esta pesquisa representou um estudo relevante para a área de Turismo e Eventos, e foi satisfatória para compreender a importância de um Curso voltado à prática de eventos.
Palavras-chave: Avaliação. Aprendizado. Eventos. Prática.