bluuebunny/crossref_metadata_2025_split huggingface dataset:
El regionalismo post-liberal en Sudamérica: ¿en fase de despolitización? Los casos de ALBA, UNASUR y MERCOSUR
Authors: Alvarez María Victoria 
Published: February 2020

Luego de cinco décadas de olas de auge y decadencia, el regionalismo en Sudamérica, en los primeros años del siglo XXI, fue repensado en un diseño post-liberal. En particular, una iniciativa de complementación y de cooperación materializada en el ALBA, y un esquema de diálogo intersectorial y cooperación política, la UNASUR. Por su parte, el MERCOSUR, un esquema resiliente de la anterior ola de regionalismo sudamericano, también se renovó en clave post-liberal.
Una década después del surgimiento del regionalismo post-liberal, se asiste a una fase de pérdida de dinamismo. En este trabajo describimos los últimos desarrollos en torno a ALBA y UNASUR, así como el MERCOSUR, siguiendo la perspectiva de Dabène de ciclos de politización. El interrogante es si estos esquemas se encuentran en una fase de despolitización. Si esto es así, nos preguntamos si serán lo suficientemente resilientes como para superar dicha fase y transitar hacia una de repolitización.
Frau Ava’s, the first named German female writer’s, poem Jüngstes Gericht ‘The Last Judgement’ and its Lithuanian translation
Authors: Burov Aleksej , Vrubliauskaitė Ignė 
Published: February 2020

The present article offers an overview of several poems written by Frau Ava (1060–1127), a German poetess whose literary works are virtually unknown in Lithuania. Ava, an anchoress in Melk Abbey, is the first named German female writer, who broke ‘the deep silence of German literature’ lasting over a century (Stein 1976, 5). All poems attributed to Frau Ava are of religious character: Johannes ‘John the Baptist’ (446 lines), Leben Jesu ‘Life of Jesus’ (2418 lines), Antichrist (118 lines) and Jüngstes Gericht ‘The Last Judgement’ (406 lines), which make up an impressive biblical epic of 3388 lines. Leben Jesu, Antichrist and Jüngstes Gericht are found in the Vorau Manuscript dating the first half of the 12th century (Codex 276, 115va-125ra), whereas the Görlitz Manuscript (Codex A III. 1. 10), compiled in the 14th century but lost during World War II, contains the poem Johannes as well as the other poems mentioned above, excluding the epilogue of Jüngstes Gericht (lines 393-406).The article presents an overview of Frau Ava’s life and works as well as a Lithuanian translation of her poem Jüngstes Gericht, written in Early Middle High German (Ger. Frümittelhochdeutsch). The translation is based on Maike Glaußnitzer and Kassnadra Sperl’s text, published in 2014.
Aesthetic of carnivalesque: Johannisnacht by Uwe Timm and Lietuvis Vilniuje by Herkus Kunčius
Authors: Katinienė Violeta 
Published: February 2020

Carnivalisation in literary prose has been gaining prominence both in Lithuanian and German literature. The present paper compares two novels, namely, Johannisnacht by Uwe Timm (1996) and Lietuvis Vilniuje by Herkus Kunčius (2011), related not merely through their themes of current affairs and reflections of the past, but also through poetics which continues the tradition of Carnivalesque. Although the two authors represent distinctly different cultural and literary backgrounds of two countries (West Germany and Lithuania), the novels transcend to a common intercultural space by their similar narrative strategies and carnivalised worldview.
Out of the Closet, into the World: The Power of Puppets in Jessie Burton’s The Miniaturist
Authors: Šlapkauskaitė Rūta 
Published: February 2020

The present paper examines the tropological significance of miniature figures in Jessie Burton’s novel The Miniaturist. By highlighting the ways in which the narrative’s figural system negotiates the structural and conceptual dichotomies of human/doll, object/thing, interiority/exteriority, authenticity/artificiality, and mobility/stasis, this reading of Burton’s novel attempts to show how the literary text rethinks the social life of things and the ambiguity of subject-object relations in the seventeenth-century Netherlands. Aligned with the commercial circuits of material culture, which underscore the moral ambivalence of the novel’s Dutch society, material objects are shown to exceed their decorative function and reveal their destructive purchase on human life.
Bounds of Adj-TVaR Prediction for Aggregate Risk
Authors: Syuhada Khreshna 
Published: February 2020

In ﬁnancial and insurance industries, risks may come from several sources. It is therefore important to predict future risk by using the concept of aggregate risk. Risk measure prediction plays important role in allocating capital as well as in controlling (and avoiding) worse risk. In this paper, we consider several risk measures such as Value-at-Risk (VaR), Tail VaR (TVaR) and its extension namely Adjusted TVaR (Adj-TVaR). Speciﬁcally, we perform an upper bound for such risk measure applied for aggregate risk models. The concept and property of comonotonicity and convex order are utilized to obtain such upper bound.Keywords: Coherent property, comonotonic rv, convex order, tail property, Value-at-Risk (VaR).
Mathematical Model for MERS-COV Disease Transmission with Medical Mask Usage and Vaccination
Authors: Manaqib Muhammad , Fauziah Irma , Mujiyanti Mujiyanti 
Published: February 2020

AbstractThis study developed a model of the spread of MERS-CoV disease using the SEIR model which was added by a health mask and vaccination factor as a preventive measure. The population is divided into six subpopulations namely susceptible subpopulations not using health masks and using health masks, exposed subpopulations, infected subpopulations not using health masks and using health masks, and recovering subpopulations. The results are obtained two equilibrium points, namely disease-free equilibrium points and endemic equilibrium points. Analysis of the stability of the disease-free equilibrium point using linearization around the equilibrium point. As a result, the asymptotic stable disease-free local equilibrium point if the base reproduction number is less than one. Numerical simulation models for MERS-CoV disease are carried out in line with the analysis of model behavior.Keywords: MERS-CoV, SEIR Model, Stability Equilibrium Point, Basic Reproduction Number. AbstrakPenelitian ini mengembangkan model penyebaran penyakit MERS-CoV menggunakan model SEIR yang ditambahkan faktor masker kesehatan dan vaksinasi sebagai upaya pencegahan. Populasi dibagi menjadi enam subpopulasi yaitu subpopulasi rentan tidak menggunakan masker kesehatan dan menggunakan masker kesehatan, subpopulasi laten, subpopulasi terinfeksi tidak menggunakan masker kesehatan dan menggunakan masker kesehatan, serta subpopulasi sembuh. Hasilnya diperoleh dua titik ekuilibrium yaitu titik ekulibrium bebas penyakit dan endemik. Analisis kestabilan titik ekuilibrium bebas penyakit menggunakan linearisasi disekitar titik ekuilibrium. Hasilnya, titik ekuilibrium bebas penyakit stabil asimtotik lokal jika bilangan reproduksi dasar kurang dari satu. Simulasi numerik model untuk penyakit MERS-CoV yang dilakukan sejalan dengan analisis perilaku model.Kata kunci: MERS-CoV, Model SEIR, Kestabilan Titik Ekuilibrium, Bilangan Reproduksi Dasar.
Blind Spot Detection for Safe Sim-to-Real Transfer
Authors: Ramakrishnan Ramya , Kamar Ece , Dey Debadeepta , Horvitz Eric , Shah Julie 
Published: February 2020

Agents trained in simulation may make errors when performing actions in the real world due to mismatches between training and execution environments. These mistakes can be dangerous and difficult for the agent to discover because the agent is unable to predict them a priori. In this work, we propose the use of oracle feedback to learn a predictive model of these blind spots in order to reduce costly errors in real-world applications. We focus on blind spots in reinforcement learning (RL) that occur due to incomplete state representation: when the agent lacks necessary features to represent the true state of the world, and thus cannot distinguish between numerous states. We formalize the problem of discovering blind spots in RL as a noisy supervised learning problem with class imbalance. Our system learns models for predicting blind spots within unseen regions of the state space by combining techniques for label aggregation, calibration, and supervised learning. These models take into consideration noise emerging from different forms of oracle feedback, including demonstrations and corrections.
We evaluate our approach across two domains and demonstrate that it achieves higher predictive performance than baseline methods, and also that the learned model can be used to selectively query an oracle at execution time to prevent errors. We also empirically analyze the biases of various feedback types and how these biases influence the discovery of blind spots. Further, we include analyses of our approach that incorporate relaxed initial optimality assumptions. (Interestingly, relaxing the assumptions of an optimal oracle and an optimal simulator policy helped our models to perform better.) We also propose extensions to our method that are intended to improve performance when using corrections and demonstrations data.
ANALISIS KOMPOSISI NUKLIDA BAHAN BAKAR BEKAS REAKTOR DAYA EKSPERIMENTAL (RDE) MENGGUNAKAN MCNPX 2.6.0
Authors: Kristina Kristina , Subekti Muhammad 
Published: February 2020

ANALISIS KOMPOSISI NUKLIDA BAHAN BAKAR BEKAS REAKTOR DAYA EKSPERIMENTAL (RDE) MENGGUNAKAN MCNPX 2.6.0. Reaktor Daya Eksperimental (RDE) adalah reaktor nuklir yang dapat digunakan untuk pembangkit listrik, pembangkit panas dan untuk memproduksi hidrogen. Jenis bahan bakar RDE yang dibahas pada penelitian ini adalah sebuah pebble bergeometri bola yang di dalamnya terdapat 8335 TRISO berkisi simple cubic (SC). Satu buah TRISO dalam pebble mengandung 5 lapisan, dimana bahan fissile terdapat pada kernel yang merupakan lapisan paling dalam dengan kandungan UO2. Proses burnup pada MCNPX 2.6.0 dilakukan selama 90 hari pembakaran dan 10 tahun pendinginan dengan hasil energi burnup dan keff 1,05343 untuk autofilled TRISO in pebble (ATIP) dan 1,04651 untuk organized TRISO in pebble (OTIP). Jumlah nuklida yang terkandung sebanyak 170 nuklida (14 aktinida dan 156 nonaktinida). Aktinida dengan massa terbesar ialah 238U (2,323 gram untuk ATIP dan 2,316 untuk OTIP) dan aktivitas terbesar ialah 241Pu (7,791 Ci untuk ATIP dan 7,639 Ci untuk OTIP), sedangkan nonaktinida dengan massa terbesar ialah 16O (0,6734 gram untuk ATIP dan OTIP) dan aktivitas terbesar ialah 137Cs (4,716 Ci for ATIP untuk 4,757 Ci untuk OTIP). Kesalahan relatif keff ATIP terhadap OTIP yang diperoleh sebesar 0,661%. Kesalahan relatif yang kecil ini serta geometri kompleks OTIP yang membutuhkan waktu lama untuk didesain menyebabkan ATIP lebih direkomendasi daripada OTIP.Kata kunci : Komposisi Nuklida, Pebble, Bahan Bakar Bekas, RDE, MCNPX 2.6.0.
Kronik Karın Ağrısı Olan Çocuklardan Alınan Gaita Örneklerinde Helicobacter Pylori Gaita Antijeni Aranması Ve Endoskobik Biyopsi Örnekleriyle Karşılaştırılması
Authors: YILMAZ Mustafa , ATMACA Suzan , ÖZERCAN İbrahim Hanifi , DOĞAN Yaşar 
Published: February 2020

Amaç:
Bu çalışmada; karın ağrısı veya endoskobi endikasyonu olan çocuk hastaların
mide antrumundan alınan biyopsi örneklerinin patolojik inceleme , gaita
örneklerinde ise H.pylori antijen
varlığı araştırılarak, H.pylori kaset
testinin tanıdaki etkinliğinin araştırılması amaçlanmıştır.

Gereç ve
Yöntem: Çocuk Gastroenteroloji polikliniğine karın
ağrısı şikayeti ile başvuran, altı-on sekiz (6-18) yaşları arasında elli (50)
hastadan alınan gaita ve endoskobik biopsi örnekleri çalışma grubunda
değerlendirilmeye alındı. Kontrol grubuna ise esas yakınması karın ağrısı olmayan altı-on sekiz (6-18)
yaşları arasında elli (50) hastadan alınan gaita ve endoskobik biopsi örnekleri
dahil edildi. Gaita örneklerinde karteks yöntemi ile H.pylori antijeni ,
Endoskobik biopsi örneklerinde ise Giemsa boyama yöntemi ile H.pylori basili araştırıldı.

Bulgular: Çalışma grubundaki 50 hastanın 47 (%94)’sinin endoskobik
biopsi örneğinde H.pylori( Giemsa boyama ile) pozitif saptanmıştır. Aynı
hastaların 37 (%74)’sinde ise H.pylori gaita antijeni pozitif bulunmuştur. Kontrol
grubundaki 50 hastanın 14 (%28)’ünün endoskobik biopsi örneğinde H.pylori
pozitif bulunurken, aynı hastaların 3 (%6)’ünde H.pylori gaita antijeni saptanmıştır.
Çalışma ve kontrol grubu arsındaki
fark istatistiksel olarak (p&lt;0.05) anlamlı bulunmuştur (p=0.000).

Sonuç:
Çalışmada kullandığımız H.pylori gaita antijeni taramasının invaziv olmaması,
ucuz , kolay uygulanabilir ve patolojik
incelemeye yakın duyarlılıkta pozitif sonuç vermesi açısından H.pylori tespitinde
kullanılmasının uygun olacağı kanaatine varılmıştır.
How can Europeans enter the Kingdom of Heaven? A decolonial challenge to Western European political and public theologies in an age of migration
Authors: Field David 
Published: February 2020

In his 2019 Steve de Gruchy Memorial Lecture John de Gruchy provocatively posed the question: “Is it possible for a white South African male to enter the kingdom of heaven? The core of his concern was how is it possible for a person who was and is still a beneficiary of Apartheid and colonialism in South Africa participate in the creation of a just and transformed society. This question has a particular poignancy in contemporary South Africa where the beneficiaries of exploitation and injustice continue to live in close proximity to the victims in a society that still reflects the patterns of inequality created by Apartheid. However, the challenge of the question is not limited to one particular situation of exploitation and injustice but reverberates in numerous other contexts. South African Apartheid was an intensified microcosm of European colonialism and hence my question; “How can Europeans enter the Kingdom of Heaven?” Or to phrase it differently, how can Western European political and public theologies contribute to the creation of a just and sustainable world order, in the light of Western European colonial entanglements and Western Europe’s continued benefiting from unjust and exploitative international relationships. I pose this question as a white South African male who has lived in Europe for eighteen years and has recently acquired Swiss citizenship. Hence, the question is self-referring – it challenges the particularity of my own existence that is characterised by complicity, hybridity, and complexity of one who is a beneficiary of Apartheid, whose cultural heritage is influenced by Europe, who has deep roots in (South) Africa; who seeks to do theology while listening to the diverse voices of Africa; yet who now resides in Europe and through taking on the citizenship of a European country has grafted himself into the history and politics of Western Europe and all that this entails. So, the question is this personal – “How do I do political theology in Europe as a white South African, but also as a student of John de Gruchy?”
A New Uniform Moment Tensor Catalog for Yunnan, China, from January 2000 through December 2014
Authors: Xu Yan , Koper Keith D. , Burlacu Relu , Herrmann Robert B. , Li Dan-Ning 
Published: February 2020

AbstractBecause of the collision of the Indian and Eurasian tectonic plates, the Yunnan Province of southwestern China has some of the highest levels of seismic hazard in the world. In such a region, a catalog of moment tensors is important for estimating seismic hazard and helping understand the regional seismotectonics. Here, we present a new uniform catalog of moment tensor solutions for the Yunnan region. Using a grid-search technique to invert seismic waveforms recorded by the permanent regional network in Yunnan and the 2 yr ChinArray deployment, we present 1833 moment tensor solutions for small-to-moderate earthquakes that occurred between January 2000 and December 2014. Moment magnitudes in the new catalog vary from Mw 2.2 to 6.1, and the catalog is complete above Mw∼3.5–3.6. The moment tensors are constrained to be purely double-couple and show a variety of faulting mechanisms. Normal faulting events are mainly concentrated in northwest Yunnan, while farther south along the Sagaing fault the earthquakes are mostly thrust and strike slip. The remaining area includes all three styles of faulting but mostly strike slip. We invert the moment tensors for the regional stress field and find a strong correlation between spatially varying maximum horizontal stress and Global Positioning System observations of horizontal ground velocity. The stress field reveals clockwise rotation around the eastern Himalayan syntaxis, with northwest–southeast compression to the east of the Red River fault changing to northeast–southwest compression west of the fault. Almost 88% of the centroid depths are shallower than 16 km, consistent with a weak and ductile lower crust.
Different Immune Reconstitution between Cord Blood and unrelated Bone Marrow Transplantation with Relation to Chronic Graft-versus-Host Disease
Authors: Yoshida Hitoshi , Koike Midori , Koike Midori , Nakata Keiichi , Hino Akihisa , Fuji Shigeo , Masaie Hiroaki , Oka Chihiro , Higeno Akemi , Idota Atsushi , Yamasaki Tomoyuki , Ishikawa Jun 
Published: February 2020

Background: Advances of allogeneic hematopoietic cell transplantation (allo-HCT) have brought long-term survival to the patients with hematologic malignancies. Chronic graft-versus-host disease (GVHD) is one of major problems for the long- term survivors after allo-HCT. Dysregulation of immune reconstitution has been reported to be involved in the pathogenesis of chronic GVHD. Differences of immune reconstitution between cord blood transplantation (CBT) and unrelated bone marrow transplantation (uBMT) remain unclear in long-term survivors. We investigated immune reconstitution in patients surviving for more than 2 years after CBT (n=21) or uBMT (n=20) without relapse of underlying disease.
Materials and Methods: Using flow cytometric analysis of peripheral blood, we investigated immune reconstitution of T cells, B cells, and NK cells between CBT and uBMT patients. We collected clinical data regarding allo-HCT and examined the relation of immune reconstitution to the development of chronic GVHD.
Results: Between CBT and uBMT patients, we found significant differences in absolute cell number of CD8+ as well as CD19+ cell and CD4/CD8 ratio even more than 2 years after allo-HCT. Among uBMT patients, absolute cell number of naive CD4+ cell was significantly lower in patients with chronic GVHD. In addition, we found significant differences in absolute cell number of CD19+ cell, especially naive B cell between patients with and without chronic GVHD in both CBT and uBMT patients.
Conclusion: These results suggest that differences of immune recovery between CBT and uBMT patients may exist even in patients surviving for more than 2 years and might be related to the development of chronic GVHD.
A Single Center Study of Prescribing and Treatment Outcomes of Patients with Chronic Myeloid Leukemia
Authors: Nekoohesh Ladan , H. Ghahremani1 Mohammad , Rostami Shahrbano , Nikbakht Mohsen , Nekoohesh Leila , Naemi Roozbeh , Mohammadi Saeed , Ghadyaninejad Laya , Mousavi Seyed Asadollah , Vaezi Mohammad , Alimoghaddam Kamran , Chahardouli Bahram 
Published: February 2020

Background: The present study investigated the patients with Chronic Myeloid Leukemia in chronic phase (CP-CML) who had been on the first- line Imatinib Mesylate (IM) therapy for a period of 84 months.
Materials and Methods: This retrospective study was conducted in 295 newly-diagnosed CP-CML patients(age >18 years) who were admitted to the Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran during 1 January, 2009 to 30 December, 2016. Response to treatment was evaluated by molecular response assessment. Rates of IM dose adjustment, switching to another drug therapy, progression to Accelerate Phase (AP) and Blastic Crisis (BC) and long-term outcomes included Overall Survival (OS) and Progression Free Survival (PFS) were assesed.
Results: Patients’ average age was 41.7 years, and 52.9% were male. 44.4% of patients at the month 18 achieved Major Molecular Response (MMR). Progression to AP/BC occurred in 26 patients during 84 months, and the estimated rate of OS and PFS were 71.83 and 74.48, respectively. Among the patients who did not achieve MMR at month 18 , 61 patients were treated with IM ( 400 mg /day), and then after month 18, 24(39.3%) of whom achieved MMR. Dose adjustments occurred in 60 patients (20.33%). IM dose increase was observed in 53 patients who did not achive optimal response to imatinib or loss of optimal response. IM dose decrease was observed in 7 patients. 25 (8.47%) patients were switched to a different Tyrosine Kinase Inhibitor (TKI). Most of TKI changes(n=21) happened in patients who did not achieve optimal response to IM and TKI changes owing to adverse events of IM were observed in 4 patients.. Among the patients undergoing change in treatment, 24(43.75%) patients achieved MMR.
Conclusion: Our data showed the high effectiveness of the change in the treatment of IM-resistant condition. Moreover, our finding suggests that imatinib be effective in Iranian patients after a long period of time compared to the referenced studies.
The Effect of 5-Aza-2′-Deoxycytidine in Combination to and in Comparison with Vorinostat on DNA Methyltransferases, Histone Deacetylase 1, Glutathione S-Transferase 1 and Suppressor of Cytokine Signaling 1 Genes Expression, Cell Growth Inhibition and Apop
Authors: Sanaei Masumeh , Kavoosi Fraidoon , Esmi Zahra 
Published: February 2020

Background: Aberrant methylation and histone deacetylation of tumor suppressor genes (TSGs) are the most epigenetic alterations involving in tumorigenesis. Overexpression of DNA methyltransferases (DNMTs) and histone deacetylase 1 (HDAC1) have been reported in several cancers. The reversion of hypermethylation and deacetylation by epi-drugs such as 5-aza-2′-deoxycytidine (5-AZA-CdR) and vorinostat (SAHA) can restore normal expression of TSGs. Previously, we reported that 5-AZA-CdR and valproic acid (VPA) can inhibit DNMT1 in hepatocellular carcinoma (HCC). The aim of this study was to investigate the effect of 5-AZA-CdR in combination to and in comparison with SAHA on DNMT1, DNMT3a, DNMT3b, histone deacetylase 1 (HDAC1), glutathione S-transferase 1 (GSTP1) and suppressor of cytokine signaling 1 (SOCS1) genes expression, cell growth inhibition and apoptotic induction in hepatocellular LCL-PI 11 cell line.
Materials and Methods: The cells were treated with 5-AZA-CdR and SAHA and then MTT assay, cell apoptosis assay and Real-time quantitative RT-PCR (qRT-PCR) were done.
Results: Both agents indicated significant inhibitory and apoptotic effect (P< 0.001). The apoptotic effect of SAHA was more than that of 5-Aza-CdR. The result of qRT-PCR indicated that 5-Aza-CdR decreased DNMT1, DNMT3a, DNMT3b and increased GSTP1and SOCS1 genes expression and SAHA decreased HDAC1 and increased GSTP1 and SOCS1 genes expression significantly. Maximal apoptosis and genes expression were seen with combined treatment.
Conclusion: 5-AZA-CdR and SAHA down-regulated DNMT1, DNMT3a, DNMT3b, and HDAC1 and up-regulated GSTP1 and SOCS1 gene expression by which inhibited cell viability and induced apoptosis, suggesting that they could be used in the treatment of HCC.