bluuebunny/crossref_metadata_2025_split huggingface dataset:
El espacio en cuanto forma de los fenómenos y la tesis de la receptividad: mutua implicación
Authors: Contreras Gallegos Diana Gloria 
Published: October 2019

Mi objetivo es hacer notar que existe un nexo de mutua implicación entre dos tesis kantianas: la tesis de la receptividad (nuestro conocimiento depende de que seamos afectados por los objetos) y la tesis del espacio en cuanto forma de los fenómenos. Un tratamiento completo de la tesis de la receptividad implica el idealismo trascendental de Kant en torno al espacio. Desde mi lectura, ello en absoluto afecta al realismo empírico kantiano. Para mostrar lo anterior, exploro aquí la segunda consecuencia ("b) a la que Kant arriba tras haber presentado sus argumentos en favor de la naturaleza a priori e intuitiva del espacio en la Estética Trascendental.
Palabras clave: espacio, forma de la intuición, receptividad, idealismo trascendental, realismo empírico

Abstract:
My purpose in this paper is to point out that there is a mutual implication between two Kantian thesis: the Receptivity Thesis (our knowledge depends on being affected by objects) and the thesis of the space at a form of the phenomena; so that, a full treatment of the receptivity thesis implies Kant's transcendental idealism of space. On my reading this doesn't compromise Kant's empirical realism. In order to show this I explore here the second consequence ("b") that Kant arrives after he shows his arguments in favour of the space in the Transcendental Aesthetics.

Keywords: space, form of intuition, receptivity, transcendental idealism, empirical realism
La deducción metafísica de las ideas a partir de las formas del silogismo
Authors: Caimi Mario Pedro Miguel 
Published: October 2019

Kant sostiene, en la Crítica de la razón pura y en otros textos, que las ideas de la razón se originan en las formas del silogismo. Llamamos deducción metafísica de las ideas a esta investigación del origen de ellas en las formas del prosilogismo. Pero si bien Kant sostiene que esa actividad lógica es el origen de las ideas, no muestra en detalle cómo se efectúa esa deducción metafísica de las ideas. En el presente trabajo se procura efectuar esa deducción
Estructura argumentativa, unidad temática y coherencia doctrinal en los Progresos de la metafísica de Immanuel Kant
Authors: Thisted Marcos Adrián 
Published: October 2019

A pesar de la importancia que la Kantforschung concede a los Progresos de la metafísica, los principales estudios dedicados a esta obra inconclusa y póstuma del filósofo crítico coinciden en considerarla como carente de una nítida unidad temática, afectada por severas anomalías en su estructura argumentativa y con diversas incoherencias desde el punto de vista doctrinal. A partir de una revisión crítica de la edición de los textos efectuada por Friedrich T. Rink, nuestra contribución se propone indicar cuál sería la unidad temática de esta obra, identificar sus pilares argumentativos y, por último, establecer su coherencia doctrinal.
Paula Órdenes y Anna Pickhan (eds.): Teleologische Reflexion in Kants Philosophie, Weisbaden, Springer, 2019
Authors: Reyna Fortes Rafael 
Published: October 2019

Reseña del libro:
Órdenes, P. y Pickhan, A., “Teleologische Reflexion in Kants Philosophie”. Springer, Wiesbaden, pp. 310. ISBN 978-3-658-23693-9
STUDI FENOMENOLOGI: MEKANISME KOPING PEREMPUAN YANG BELUM MEMPUNYAI KETURUNAN DITINJAU DARI ASPEK BUDAYA MINANGKABAU
Authors: Rahmaniza Rahmaniza , Riasmini Ni Made , Netrida Netrida 
Published: October 2019

Phenomenology Study: Coping Mechanism of Women No Heredity Viewed by Minangkabau Culture. The Minangkabau tribe adheres to the matrilineal kinship system. Based on this system, when a woman suffers infertility, so it means the family has not the next generation, and the line of descent will cut off. This condition makes the women need to have a coping mechanism to avoid psychology problems, including depression, anxiety, stress, neglected, discrimination, under pressure to divorce, and perceive abused. The study aimed to explore the coping mechanism of infertility women in the context of Minangkabau culture. This phenomenology study applied an in-depth interview, which involved ten women who were selected through a snowball sampling technique. Collaizi’s analysis method resulted in six themes. Those themes are through psychological and social change, obtain a response from others, the views of Minangkabau culture, adaptive coping used by women no heredity, the families were main source support, community social support. The findings strengthen the justification to involve psycho-social aspects in the infertility treatment.Keywords: Coping mechanism, infertile women, Minangkabau culture Abstrak Suku Minangkabau menganut sistem kekerabatan matrilineal. Berdasarkan sistem ini, ketika seorang wanita menderita kemandulan, itu berarti keluarga tidak memiliki generasi berikutnya, dan garis keturunan akan terputus. Kondisi ini membuat perempuan perlu memiliki mekanisme koping untuk menghindari masalah psikologi, termasuk depresi, kecemasan, stres, diabaikan, diskriminasi, di bawah tekanan untuk bercerai, dan juga merasa dilecehkan. Penelitian ini bertujuan untuk mengeksplorasi mekanisme koping wanita infertilitas dalam konteks budaya Minangkabau. Studi fenomenologi ini menerapkan wawancara mendalam yang melibatkan sepuluh wanita yang dipilih melalui teknik pengambilan sampel bola salju. Melalui metode analisis dari Collaizi, menghasilkan enam tema. Tema-tema tersebut termasuk Mengalami perubahan psikologis dan perubahan sosial, mendapat respon dari orang sekitarnya, pandangan budaya Minangkabau, koping adaptif yang digunakan oleh perempuan belum mempunyai keturunan, keluarga menjadi sumber dukungan utama, dukungan sosial dari masyarakat. Temuan ini memperkuat pembenaran untuk melibatkan aspek psiko-sosial dalam pengobatan infertilitas. Kata kunci: Budaya Mingkabau, mekanisme koping, perempuan infertile
Problem gamblers spend less money when loot boxes are removed from a game: a before and after study of Heroes of the Storm
Authors: Zendle David 
Published: October 2019

Loot boxes are items in video games that may be paid for with real-world money, but which contain randomised contents. There is a reliable correlation between loot box spending and problem gambling severity: the more money gamers spend on loot boxes, the more severe their problem gambling tends to be. However, it is unclear whether this link represents a case in which loot box spending causes problem gambling; a case in which the gambling-like nature of loot boxes cause problem gamblers to spend more money; or whether it simply represents a case in which there is a general dysregulation in in-game spending amongst problem gamblers, nonspecific to loot boxes. The multiplayer video game Heroes of the Storm recently removed loot boxes. In order to better understand links between loot boxes and problem gambling, we conducted an analysis of players of Heroes of the Storm (n = 112) both before and after the removal of loot boxes. There were a complex pattern of results. In general, when loot boxes were removed from Heroes of the Storm, problem gamblers appeared to spend significantly less money in-game in contrast to other groups. These results suggest that the presence of loot boxes in a game may lead to problem gamblers spending more money in-game. It therefore seems possible that links between loot box spending and problem gambling are not due to a general dysregulation in in-game spending amongst problem gamblers, but rather are to do with specific features of loot boxes themselves.
CLUBE DE CIÊNCIAS: REVISÃO SISTEMÁTICA DE LITERATURA DAS PRODUÇÕES STRICTO SENSU DOS ÚLTIMOS QUINZE ANOS / SCIENCE CLUB: A SYSTEMATIC REVIEW OF STRICTO SENSU LITERATURE OVER THE LAST FIFTEEN YEARS
Authors: Gonçalves Tatiane Alves , Denardin Luciano 
Published: October 2019

Neste trabalho discute-se os resultados de uma revisão sistemática de literatura sobre clube de ciências, conduzida de acordo com as etapas preconizadas por Khan, Kunz e Kleijnen (2003). A fonte de busca foi a Biblioteca Digital Brasileira de Teses e Dissertações, resultando em um corpus de pesquisa constituído por 17 produções. Como resultados que emergiram da análise das produções inventariadas destacam-se que a maioria dos participantes das pesquisas são estudantes dos anos finais do ensino fundamental. A maioria das produções objetivavam avaliar se as ações realizadas nos clubes de ciências contribuíam para a alfabetização científica. Outros trabalhos visavam analisar atividades investigativas ou avaliar produtos educacionais aplicados nesses espaços. Concluiu-se que os clubes de ciências contribuem para o desenvolvimento de uma cultura científica escolar e suprem a falta de estrutura e de tempo curricular dos professores no que diz respeito ao desenvolvimento de atividades experimentais em aulas regulares.
O CÁLCULO E OS TRÊS MUNDOS DA MATEMÁTICA: UM ESTADO DO CONHECIMENTO / THE CALCULUS AND THE THREE WORLDS OF MATHEMATICS: A STATE OF KNOWLEDGE
Authors: Bueno Rafael Winicius da Silva , Viali Lori 
Published: October 2019

O presente artigo apresenta uma pesquisa realizada com o objetivo de sistematizar e analisar a produção científica brasileira, em nível de pós-graduação stricto sensu, envolvendo o ensino e aprendizagem de conceitos relativos ao Cálculo, no contexto da teoria dos Três Mundos da Matemática. Para tanto, primeiramente foi selecionado o corpus de análise do estudo, sendo, então, realizada a leitura flutuante dos textos para a constituição das bibliografias anotada, sistematizada e categorizada. Analisando as informações encontradas, percebeu-se que ainda são poucas as pesquisas realizadas na perspectiva investigada e que as existentes se concentram no conceito de derivada e no ensino e aprendizagem voltado para cursos de Engenharia. Nesse sentido, a ausência de trabalhos abordando o conceito de Integral, no contexto de Cursos de Licenciatura em Matemática, sob a ótica da teoria dos Três Mundos da Matemática, aponta uma direção e um sentido que ainda podem explorados em futuras investigações.
Palladium‐Catalyzed Synthesis of Benzothiophenes via Cross‐Dehydrogenative Coupling of 4‐Arylthiocoumarins and Pyrones
Authors: Zhang Jin , Zhuang Yuyu , Ma Yangmin , Yang Xiufang , Szostak Michal 
Published: October 2019

AbstractBenzothiophenes represent a pivotal class of sulfur heterocycles and their synthesis has attracted significant attention to generate bioactive scaffolds. Herein, we report a convergent, atom‐ and step‐economic method for the synthesis benzothiophenes by cross‐dehydrogenative coupling (CDC) of 4‐arylthiocoumarins in good to excellent yields. We further demonstrate cross‐dehydrogenative coupling of 4‐arylthio‐2‐pyrones to afford alternative substitution of benzothiophenes. The presence of a labile ester carbonyl moiety provides functional handle for further functionalization by coumarin deconstruction. Most crucially, the manuscript demonstrates that the use of readily accessible templated synthesis has a significant potential for the rapid assembly of sulfur heterocycles by dehydrogenative coupling mechanism.magnified image
Flexible parametric model for survival data subject to dependent censoring
Authors: Deresa Negera Wakgari , Van Keilegom Ingrid 
Published: October 2019

AbstractWhen modeling survival data, it is common to assume that the (log‐transformed) survival time (T) is conditionally independent of the (log‐transformed) censoring time (C) given a set of covariates. There are numerous situations in which this assumption is not realistic, and a number of correction procedures have been developed for different models. However, in most cases, either some prior knowledge about the association betweenTandCis required, or some auxiliary information or data is/are supposed to be available. When this is not the case, the application of many existing methods turns out to be limited. The goal of this paper is to overcome this problem by developing a flexible parametric model, that is a type of transformed linear model. We show that the association betweenTandCis identifiable in this model. The performance of the proposed method is investigated both in an asymptotic way and through finite sample simulations. We also develop a formal goodness‐of‐fit test approach to assess the quality of the fitted model. Finally, the approach is applied to data coming from a study on liver transplants.
Comprehensive quantification of purine and pyrimidine metabolism in Alzheimer's disease postmortem cerebrospinal fluid by LC–MS/MS with metal‐free column
Authors: Muguruma Yoshio , Tsutsui Haruhito , Akatsu Hiroyasu , Inoue Koichi 
Published: October 2019

AbstractThe metabolome presence of nucleobases, nucleosides, nucleotides and related phosphorylated metabolites has been examined for Alzheimer's disease (AD). Although reversed‐phase liquid chromatography tandem mass spectrometry (LC–MS/MS) has been used for the determination of these analytes, they were limited in chromatographic signal intensity and reproducibility owing to significant peak tailing caused by complexing with metallic cations and phosphate groups. In this work, we applied LC–MS/MS analysis with a metal‐free column for comprehensive quantification of 40 analytes regarding to purine and pyrimidine metabolism in postmortem cerebrospinal fluid (pCSF) from AD patients. For the analytical column, an InertSustain AQ‐C18 metal‐free PEEK column was used. MS detection was by electrospray positive ionization. The metal‐free column allowed for sharp peak detection of highly polar metabolites within a running time of 17 min. In validation, the limits of detection (LOD), the limit of quantitation (LOQ) and recovery value using a pooled pCSF sample are 1–500  nM, 0.5–250 nM and a range of 53.1–144.0% (RSD ranged from 0.4 to 19.6%). The developed LC–MS/MS method utilizing a metal‐free column provides an accurate quantification of some metabolites regarding purine and pyrimidine metabolism in pCSF samples obtained from AD patients.
Differentiating Diffusivity in Different Channels of ZSM‐5 Zeolite by Pulsed Field Gradient (PFG) NMR
Authors: Zeng Shu , Xu Shutao , Gao Shushu , Gao Mingbin , Zhang Wenna , Wei Yingxu , Liu Zhongmin 
Published: October 2019

AbstractDifferentiating the diffusivity in straight channel and sinusoidal channel of ZSM‐5 zeolite is a prerequisite for catalyst optimization for the required product distribution with specific orientation. Herein, the intracrystalline diffusivities of n‐butane and iso‐butane in power ZSM‐5 zeolite were investigated by pulse field gradient (PFG) NMR, respectively. Different diffusion behaviors of the selected isomers were revealed. The effective self‐diffusion coefficient of n‐butane is about three orders of magnitude higher than that of iso‐butane. For the selected isomers, the opposite loading‐dependence were presented in self‐diffusion coefficients. Moreover, an equation containing diffusion tensors in different directions in orthogonal coordinate was successfully applied to fit the diffusion coefficients of n‐butane in straight and sinusoidal channel of ZSM‐5, respectively. The diffusivity of n‐butane in straight channel is nearly one order of magnitude faster than that in sinusoidal channel, predicting its dominant diffusion path.
Mixed‐phenotype acute leukemia: A cohort and consensus research strategy from the Children’s Oncology Group Acute Leukemia of Ambiguous Lineage Task Force
Authors: Orgel Etan , Alexander Thomas B. , Wood Brent L. , Kahwash Samir B. , Devidas Meenakshi , Dai Yunfeng , Alonzo Todd A. , Mullighan Charles G. , Inaba Hiroto , Hunger Stephen P. , Raetz Elizabeth A. , Gamis Alan S. , Rabin Karen R. , Carroll Andrew J. , Heerema Nyla A. , Berman Jason N. , Woods William G. , Loh Mignon L. , Zweidler‐McKay Patrick A. , Horan John T. ,   for the Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task Force
Published: October 2019

BackgroundOptimal chemotherapy for treating mixed‐phenotype acute leukemia (MPAL) and the role of hematopoietic stem cell transplantation (HSCT) remain uncertain. Major limitations in interpreting available data are MPAL's rarity and the use of definitions other than the currently widely accepted criteria: the World Health Organization 2016 (WHO2016) classification.MethodsTo assess the relative efficacy of chemotherapy types for treating pediatric MPAL, the Children's Oncology Group (COG) Acute Leukemia of Ambiguous Lineage Task Force assembled a retrospective cohort of centrally reviewed WHO2016 MPAL cases selected from banking studies for acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Patients were not treated in COG trials; treatment and outcome data were captured separately. The findings were then integrated with the available, mixed literature to develop a prospective trial in pediatric MPAL.ResultsThe central review confirmed that 54 of 70 cases fulfilled WHO2016 criteria for MPAL. ALL induction regimens achieved remission in 72% of the cases (28 of 39), whereas AML regimens achieved remission in 69% (9 of 13). The 5‐year event‐free survival (EFS) and overall survival (OS) rates for the entire cohort were 72% ± 8% and 77% ± 7%, respectively. EFS and OS were 75% ± 13% and 84% ± 11%, respectively, for those receiving ALL chemotherapy alone without HSCT (n = 21).ConclusionsThe results of the COG MPAL cohort and a literature review suggest that ALL chemotherapy without HSCT may be the preferred initial therapy. A prospective trial within the COG is proposed to investigate this approach; AML chemotherapy and/or HSCT will be reserved for those with treatment failure as assessed by minimal residual disease. Embedded biology studies will provide further insight into MPAL genomics.
Approaches for the evaluation of favorable shale gas areas and applications: Implications for China's exploration strategy
Authors: Li Zhen , Zhang Jinchuan , Tang Xuan , Gao Yu , Huo Zhipeng , Li Pei , Liu Junlan , Gong Dajian 
Published: October 2019

AbstractTo explore practical approaches for the evaluation of favorable shale gas areas, a structural decomposition analysis with respect to the index system, evaluation criteria, weight determination, and evaluation methods was carried out. Five types of indexes were determined from 25 subindexes that formed the index system, and improved whitenization weight functions are proposed to establish evaluation criteria. The index weights calculated using entropy weight and Euclidean distance methods are consistent, whereas the weights determined by gray relational analysis are significantly affected by the relative number of indexes and evaluation objects, selected mother factor, and resolution coefficient. The significant linear positive correlation between the relative approach degree values calculated using TOPSIS and the scores obtained using fuzzy comprehensive evaluation (FCE) is indicative of a consistent evaluation result, but it should be noted that extreme indicator values can have strong effects on the evaluation using the fuzzy similarity method. Finally, an exploration strategy for China's shale gas is suggested: Areas with weak reformation and relatively low maturity are expected to be favorable for marine shale production in South China, and continental and transitional shale‐bearing basins are promising for the prospecting multiple‐origin shale gas and coal measure gas, respectively.
Impacts of Holocene and modern sea‐level changes on estuarine mangroves from northeastern Brazil
Authors: Cohen Marcelo C.L. , Figueiredo Beatriz L. , Oliveira Nedra N. , Fontes Neuza A. , França Marlon Carlos , Pessenda Luiz C.R. , de Souza Adriana V. , Macario Kita , Giannini Paulo C.F. , Bendassolli José A. , Lima Paula 
Published: October 2019

AbstractProjections of the impacts of modern Relative Sea Level (RSL) rise on estuarine mangroves should be supported by coastal topographic data and records of mangrove dynamics under past RSL change. This work identified inland and seaward mangrove migrations along the Jucuruçu River (Bahia, Northeastern Brazil), during the Holocene based on sedimentary features, palynological and geochemical (δ13C, δ15N, C/N) data integrated with digital elevation models. During the Middle Holocene, in response to RSL rise, the estuary saw mangrove forest establish up to ~37 km inland. RSL stood between ‐1.4 (+0.36/‐2.2 m) and +1 (2.19/0.2 m) around 7400 cal yr BP, and rose to a highest position of +3.25 (4.22/2.45 m) reached around 5350 cal yr BP. That marine incursion caused the inland replacement of freshwater vegetation by mangroves on tidal flats. Since then, the estuary experienced RSL fall, reducing inland tidal water salinity towards the Late Holocene, making that the mangroves were replaced by freshwater floodplain vegetation. Today, in the seaward part of the estuary near its mouth, mangroves occupy an area of ~10 km2 along tidal channels. Considering a RSL rise of 98 cm up to the end of the 21st century, at a rate significantly higher than that of Middle Holocene RSL rise (1.5 mm/yr) and fall (0.6 mm/yr), the current mangrove substrates are expected to drown and/or eroded near the coast, while new mangroves may establish inland, at topographically higher tidal flats in nowadays freshwater‐tidal zones. Mangrove area could expand over 13 km2 of coastal and flood plain. Following the same interaction between RSL/climate changes and Holocene mangrove dynamics, such upstream mangrove migration may be attenuated or intensified by changes in fluvial discharge. © 2019 John Wiley & Sons, Ltd.
Deglaciation history at the Alpine‐Mediterranean transition (Argentera‐Mercantour, SW Alps) from 10Be dating of moraines and glacially polished bedrock
Authors: Rolland Yann , Darnault Romain , Braucher Régis , Bourlès Didier , Petit Carole , Bouissou Stéphane ,   ASTER Team
Published: October 2019

AbstractEstimating the extent and age of the last glacial maxima as well as the chronology of glacial recessions in various environmental contexts is key to source‐to‐sink studies and paleoclimate reconstructions. The Argentera‐Mercantour massif is located at the transition between the Alps and the Mediterranean Sea, therefore, its deglaciation chronology can be compared to the sediment budget of the Var River basin. Based on 13 new cosmic‐ray exposure (CRE) beryllium‐10 (10Be) datings performed on moraines and polished crystalline bedrocks and 22 reassessed 10Be CRE ages from similar altitude nearby steep basement surfaces, and from a lake sediment core, we can constrain the deglaciation chronology of the Argentera‐Mercantour massif. These data allow for the first time to fully reconstruct the deglaciation history at the scale of the entire massif in agreement with a major glacier recession at c. 15 ka, at the onset of Bølling transition between the Oldest and Older Dryas. Main deglaciation of the upper slopes [2700–2800 m above sea level (a.s.l.)] occurred after the Last Glacial Maximum (LGM) at 20.8–18.6 ka, followed by the main deglaciation of the lower slopes (2300 m a.s.l.) at 15.3–14.2 ka. Finally, the flat polished surfaces above 2600 m a.s.l. and the zones confined within narrow lateral valleys were likely affected by progressive ice melting of remaining debris covered glaciers and moraine erosion following the Younger Dryas re‐advance stage between 12 and 8–9 ka. At lower elevations, the Vens Lake located at 2300 m a.s.l., allows evidence of the onset of lake sedimentation at c. 14 ka and a transition towards a vegetated environment that mainly occurred before 8 ka. Moraine final stabilization at 5 ka might reflect denudation acceleration during the Holocene humid phase. This contribution reveals a glacier–climate relationship more sensitive to warming phases in the southern Alps highlighted by a major decrease of glaciers after c. 15 ka. This major deglaciation is correlated with a 2.5‐fold decrease of sediment discharge of rivers into the Mediterranean Sea. © 2019 John Wiley & Sons, Ltd.