bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does youth matter? Long-term effects of youth characteristics on the diversity of partnership trajectories
Authors: Jung Jana 
Published: October 2020

Previous research has mainly concentrated on the study of certain transitions and the influence of economic and socio-structural factors on partnership status. From a life course perspective, it remains unclear how factors anchored in youth are related to the diversity of partnership biographies. Arguing that individuals act and behave based on prior experiences and resources, I analyse how personal and social resources as well as socio-demographic characteristics influence the turbulence of longitudinal partnership trajectories.Using a longitudinal dataset from the German LifE Study, I examine partnership histories from the ages 16 to 45. The results suggest that in addition to the influence of an individual’s socio-demographic placement (for example, religious commitment and regional living conditions), personal and social resources anchored in youth also have a long-term effect on the diversity of partnership trajectories. This article shows that women are influenced by their attitudes towards marriage and family, while men are influenced by their attitudes towards their careers.
How COVID-19 May Change the World of Services to People With Intellectual and Developmental Disabilities
Authors: Bradley Valerie J. 
Published: October 2020

Abstract
The COVID-19 epidemic caused disruption and dislocation in the lives of people with disabilities, their families, and providers. What we have learned during this period regarding the strengths and weaknesses of the service system for people with disabilities should provide a roadmap for building a more robust and agile system going forward. Based on a canvas of leaders in our field, I propose a way of outlining a reimagined system.
The Sibling-in-Law: Understanding an Unknown Member of the Disability Community
Authors: Zemke Kirsten E. , Burke Meghan M. , Urbano Richard C. , Hodapp Robert M. 
Published: October 2020

Abstract
Little attention has focused on siblings-in-law, the spouses of siblings of people with disabilities. Using an online survey, 102 siblings-in-law provided information concerning themselves, their spouses, in-law family, and experiences. Overall experiences were rated as positive (51.0%), mixed (34.3%), or negative (14.7%). Compared to respondents with negative outcomes, respondents with positive and mixed outcomes felt being a sibling-in-law more positively impacted their marriage, relationship with in-laws, parenting, desire to advocate, and career. Before marriage, these two groups better understood sibling-in-law responsibilities and reported less worry about marrying into a family with a member with disabilities or having children with disabilities. In open-ended reflections, 1/3 of respondents discussed family dynamics; improving disability knowledge; future planning; and marriage considerations. Practice and research implications are discussed.
Comparative analysis of stimulated Brillouin scattering at 2  µm in various infrared glass-based optical fibers
Authors: Deroh M. , Beugnot J.-C. , Hammani K. , Finot C. , Fatome J. , Smektala F. , Maillotte H. , Sylvestre T. , Kibler B. 
Published: October 2020

We provide experimental characterization of stimulated Brillouin scattering at 2-µm wavelength in step-index optical fibers made of various types of infrared materials. Our results show that the main characteristics of the Brillouin process such as the frequency shift, spectral linewidth, and gain can be widely tuned through the index-controlled guiding of both acoustic and optical waves as well as the intrinsic material properties of the fiber under test. More precisely, we found that depending on the used material the Brillouin frequency shift can be decreased by 30% in a common step-index fiber design, while its linewidth and gain efficiency can be increased by a factor 5 and 180, respectively, when compared with the standard silica fiber. Four families of fiber materials were analyzed near 2 µm as well as at 1.55 µm for comparison—namely, germanosilicate, zirconium fluoride, tellurium oxide, and sulfur-based chalcogenide. Our findings open the way for further fundamental investigations of stimulated Brillouin scattering and the development of practical applications in the 2-µm spectral range.
Data Storytelling als kritischer Erfolgsfaktor von Data Science
Authors: Neifer Thomas , Lawo Dennis , Bossauer Paul , Esau Margarita , Jerofejev Anna-Maria 
Published: October 2020

ZusammenfassungBedingt durch die fortlaufende Digitalisierung und den Big Data-Trend stehen immer mehr Daten zur Verfügung. Daraus resultieren viele Potenziale – gerade für Unternehmen. Die Fähigkeit zur Bewältigung und Auswertung dieser Daten schlägt sich in der Rolle des Data Scientist nieder, welcher aktuell einer der gefragtesten Berufe ist. Allerdings ist die Integration von Daten in Unternehmensstrategie und -kultur eine große Herausforderung. So müssen komplexe Daten und Analyseergebnisse auch nicht datenaffinen Stakeholdern kommuniziert werden. Hier kommt dem Data Storytelling eine entscheidende Rolle zu, denn um mit Daten eine Veränderung hervorrufen zu können, müssen vorerst Verständnis und Motivation für den Sachverhalt zielgruppenspezifisch geschaffen werden. Allerdings handelt es sich bei Data Storytelling noch um ein Nischenthema. Diese Arbeit leitet mithilfe einer systematischen Literaturanalyse die Erfolgsfaktoren von Data Storytelling für eine effektive und effiziente Kommunikation von Daten her, um Data Scientists in Forschung und Praxis bei der Kommunikation der Daten und Ergebnisse zu unterstützen.
The City Beneath: A Century of Los Angeles Graffiti, Susan A. Phillips (2019)
Authors: Lennon John F. 
Published: October 2020

Review of: The City Beneath: A Century of Los Angeles Graffiti, Susan A. Phillips (2019)
New Haven: Yale University Press, 320 pp.,
ISBN 978-0-30024-603-2, h/bk, $50
An Herbal Formulation of Jiawei Xiaoyao for the Treatment of Functional Dyspepsia: A Multicenter, Randomized, Placebo-Controlled, Clinical Trial
Authors: Chen Guang , Feng Peimin , Wang Shaofeng , Ding Xiangping , Xiong Jiaying , Wu Jianhua , Wang Lihua , Chen Wei , Chen Guixia , Han Mei , Zou Ting , Li Lei , Du Hongbo 
Published: October 2020

INTRODUCTION:
To investigate the efficacy and safety of an herbal formulation of Jiawei Xiaoyao (JX) on gastrointestinal symptoms in patients with functional dyspepsia (FD) who had previously rejected standard therapies of proton pump inhibitors, H2 blockers, or Helicobacter pylori eradication.

METHODS:
A total of 144 adult men and women with FD according to the Rome III criteria were recruited at 9 sites in China from August 2017 to April 2019. Participants were randomized to receive either a JX pill or placebo (12 g/d, 6 g twice a day) for 4 weeks. The primary end point was the change in the total Gastrointestinal Symptom Score (GIS) from baseline to week 4. The secondary end points included the scores on the Hamilton Depression Scale and the Hamilton Anxiety Scale. The safety outcomes included the results of the complete blood count, the liver function test, the renal function test, urinalysis, the fecal occult blood test, and an electrocardiogram.

RESULTS:
Data from 141 patients (JX pill, n = 70; placebo, n = 71) were statistically analyzed. The mean ± SD of the GIS for the JX pill group at baseline and 4 weeks was 9.3 ± 3.1 and 3.8 ± 3.0, respectively; the mean ± SD of the GIS for the placebo group at baseline and 4 weeks was 9.5 ± 3.4 and 5.3 ± 4.4, respectively (change from baseline to 4 weeks in the JX pill group vs change from baseline in the control group, −1.3 points; P = 0.013). The JX pill group showed greater improvement in both the Hamilton Depression Scale and Hamilton Anxiety Scale scores from baseline to 4 weeks than the placebo group, but the difference was not significant. The total number of adverse events was 30 in the JX pill group vs 20 in the placebo group (P = 0.240).

DISCUSSION:
The JX pill was superior to the placebo in terms of improving the GIS in patients with FD but did not significantly improve depression or anxiety symptoms. These findings suggest that the JX pill may have a positive effect on the resolution of gastrointestinal symptoms in patients with FD who are seeking alternative therapies.
Disparities in the Diagnosis and Treatment of Gastric Cancer in Relation to Disabilities
Authors: Kim Hyoung Woo , Shin Dong Wook , Yeob Kyoung Eun , Cho In Young , Kim So Young , Park Seon Mee , Park Jong Heon , Park Jong Hyock , Kawachi Ichiro 
Published: October 2020

INTRODUCTION:
We investigated potential disparities in the diagnosis, treatment, and survival of gastric cancer (GC) patients with and without disabilities.

METHODS:
We linked Korean National Disability Registry data with the Korean National Health Insurance database and Korean Central Cancer Registry data. This study included a total of 16,849 people with disabilities and 58,872 age- and sex-matched control subjects in whom GC had been diagnosed.

RESULTS:
When compared to GC patients without disabilities, patients with disabilities tended to be diagnosed at a later stage (localized stage 53.7% vs 59.0% or stage unknown 10.7% vs 6.9%), especially those with severe disabilities (P < 0.001). This was more evident in patients with mental impairment (localized stage 41.7% and stage unknown 15.2%). In addition, not receiving treatment was more common in patients with disabilities than those without disabilities (29.3% vs 27.2%, P < 0.001), and this disparity was more evident in those with severe disabilities (35.4%) and in those with communication (36.9%) and mental (32.3%) impairment. Patients with disabilities were at slightly higher risk of overall mortality as well as GC-specific mortality compared to people without disabilities (adjusted hazard ratio [aHR] = 1.18, 95% confidence interval: 1.14–1.21 and aHR = 1.12, 95% confidence interval: 1.09–1.16, respectively), and these disparities were more pronounced in those with severe disabilities (aHR = 1.62 and 1.51, respectively).

DISCUSSION:
Patients with disabilities, especially severe disabilities, were diagnosed with GC at a later stage, received less staging evaluation and treatment, and their overall survival rate was slightly worse compared to those without disabilities.
Independent Validation of a Tissue Systems Pathology Assay to Predict Future Progression in Nondysplastic Barrett's Esophagus: A Spatial-Temporal Analysis
Authors: Frei Nicola F. , Konte Kadère , Bossart Emily A. , Stebbins Katelyn , Zhang Yi , Pouw Roos E. , Critchley-Thorne Rebecca J. , Bergman Jacques J.G.H.M. 
Published: October 2020

INTRODUCTION:
An automated risk prediction assay has previously been shown to objectively identify patients with nondysplastic Barrett's esophagus (NDBE) who are at increased risk of malignant progression. To evaluate the predictive performance of the assay in 76 patients with NDBE of which 38 progressed to high-grade dysplasia/esophageal adenocarcinoma (progressors) and 38 did not (nonprogressors) and to determine whether assessment of additional (spatial) levels per endoscopy and/or multiple (temporal) time points improves assay performance.

METHODS:
In a blinded, nested case-control cohort, progressors and nonprogressors were matched (age, sex, and Barrett's esophagus length). All random biopsy levels from the baseline endoscopy (spatial samples) and all available previous endoscopies back to 10 years before progression (temporal samples) were assayed. Because the 1:1 ratio of progressors to nonprogressors does not reflect the real-world Barrett's population, negative and positive predictive values were adjusted for prevalence.

RESULTS:
Seventy-six patients (58 men), mean age of 63 ± 9 years, were studied. A high-risk score was associated with a prevalence-adjusted annual progression rate of 6.9%. The assay identified 31% of progressors when assessing a single biopsy level from the baseline endoscopy. Sensitivity increased to 50% and 69% in spatial and temporal analyses, respectively, while specificity remained at 95%.

DISCUSSION:
The assay identified a significant subset of NDBE patients who progress at a rate comparable with published estimates for expert-confirmed low-grade dysplasia. Assessing additional spatial and temporal biopsies increased the predictive accuracy, allowing for identification of most future progressors. Additional studies will evaluate the predictive performance of the assay in low-prevalence settings.
Clinical characteristics, surgical approach, BRAFV600E mutation and sodium iodine symporter expression in pediatric patients with thyroid carcinoma
Authors: Castro Paula , Patiño Esteban , Fierro Fernando , Rojas Carolina , Buitrago Giancarlo , Olaya Natalia 
Published: October 2020

Abstract

Objectives
Thyroid cancer is the most common endocrine neoplasm in childhood. There are few studies characterizing pediatric population in Colombia. We intend to detail the clinical, histological characteristics, BRAFV600E mutational status and NIS (sodium-iodine symporter) expression of children with papillary thyroid carcinoma (PTC) managed at Hospital de La Misericordia.

Methods
Medical records of the Department of Pediatric Surgery and Pathology from 2009 to 2018 were scrutinized in search of cases of differentiated thyroid carcinoma. A descriptive analysis was made. Paraffin embedded tumoral tissue was recovered to assess BRAF V600E mutational status by PCR and NIS expression by immunohistochemistry.

Results
Sixteen patients were selected, 81.2% were girls. Average age of presentation was 11.8 years. Only one patient had previous radiation exposure. Most frequent symptom was cervical adenopathy with a mean time of 29.2 weeks before diagnosis. 93.7% underwent total thyroidectomy and lymphadenectomy. 62.5% were PTC combining both classic and follicular pattern. 6.25% cases had BRAFV600E mutation and 25% showed NIS focal reactivity.

Conclusions
We found greater female predominance, lower percentage of risk factors described and a high percentage of patients requiring aggressive surgical treatment. We consider important to contemplate thyroid cancer as a differential diagnosis of cervical lymph node enlargement in children. Diagnosis can be challenging in benign and indeterminate categories of the FNA cytology and biomolecular profiles such as BRAF and NIS could be determinant in guiding treatment. More studies with larger sample size, complete genetic analysis, evaluation to iodine response and long term follow up are required.
Photoinduced electron transfer processes of single-wall carbon nanotube (SWCNT)–based hybrids
Authors: Du Lili , Xiong Wenjuan , Chan Wai Kin , Phillips David Lee 
Published: October 2020

Abstract
In this review, noncovalent functionalization of single-wall carbon nanotubes (SWCNTs) is briefly reviewed. The functional materials summarized here include metalloporphyrin derivatives, biomolecules and conjugated polymers. Notably, time-resolved spectroscopic techniques such as time-resolved fluorescence and transient absorption were employed to directly investigate the electron transfer and recombination processes between the functionalities and the SWCNTs. In addition, Raman spectroscopy is also useful to identify the interaction and the electron transfer direction between both the functionalities and the SWCNTs. An improved understanding of the mechanisms of these SWCNT-based nanohybrids in terms of their structural and photophysical properties can provide more insights into the design of new electronic materials.
Coda: Ten Questions on Globality
Authors: Editors The , Chakrabarty Dipesh 
Published: October 2020

Abstract
Dipesh Chakrabarty is Lawrence A. Kimpton Distinguished Service Professor in History and South Asian Languages and Civilizations at the University of Chicago. He is the author of several books, including The Crises of Civilization (2018) and Provincializing Europe (2000); and was one of the principal founders of the editorial collective of Subaltern Studies. In this discussion he ruminates upon the state of globality; its relationship to the planet Earth; the scope and possible duration of the Anthropocene; and some of globalization's consequences for humanity and human understanding. The interview was conducted by managing editor, Kenneth Weisbrode.
Squeal Noise Analysis Using A Combination of Nonlinear Friction Contact Model
Authors: Rusli M. , Fesa M.H. , Dahlan H. , Bur M. 
Published: October 2020

Squeal noise is generated by an unstable friction-induced vibration in a mechanical structure with friction load. Nonlinear mechanisms like sprag-slip, stick-slip, and negative frictions damping are believed in contributing to generate this kind of noise. However, the prediction of its occurrence still counts on the analysis of complex-linear eigenvalue, which may underpredict the number of unstable vibration modes. The structure also is found to seem to generate squeal noise randomly. In this paper, nonlinear analysis of a squeal noise is investigated. The study is conducted numerically by a simple two-degree of freedom model and an experimental observation using a circular and slider plate with a friction contact interface. The friction force is modeled as a function cubic nonlinear contact stiffness and nonlinear negative velocity function of friction coefficient. It is found that mode coupling instability will occur if the normal contact stiffness and friction coefficient exceed the bifurcation point to generate a couple-complex conjugate eigenvalue and eigenvector. However, when the system is stated linearly stable, instability still can appear because of increasing the nonlinear contact stiffness and coefficient of friction. The instability is affected significantly by relative velocity and pressing force. Both parameters dynamically change depending on the vibration response of the structure. Furthermore, it is also found the stick-slip phenomenon interacted with mode coupling instability to generate squeal noise. It contributes to supply energy to increase the response caused by instability of mode coupling.
Tuft Flow Visualisation on UTM-LST VFE-2 Delta Wing Model Configuration at High Angle of Attacks
Authors: Said M. , Imai M. , Mat S. , Dahalan M. N. , Mansor S. , Mohd Nasir M. N. , Nik Mohd N. A. R. 
Published: October 2020

This paper reports on flow visualisation and surface pressure measurements over the upper surface of a blunt-edged delta wing model at high angles of attack. The flow structure above the upper surface of the blunt-edged delta wing was found to be different compared to delta wing with sharp leading edge. The flow becomes more complicated especially in the leading edge region of the wing. Currently, there is no data available to verify if the primary vortex could reach the apex of the wing when the angle of attack is further increased. Most prior experiments were performed at the angles of attack, α, below 23° with only a few experiments that had gone to α = 27°. These prior experiments and some CFD works stipulated that the attached flow continue to exist in the apex region of the delta wing even at very high angles of attack above 23°. In order to verify this hypothesis, several experiments at high angles of attack were conducted in Universiti Teknologi Malaysia Low Speed wind Tunnel (UTM–LST), using a specially constructed VFE2 wing model equipped with blunt leading edges. This series of experiments employed two measurement techniques; the first was the long tuft flow visualisation method, followed by surface pressure measurements. The experiments were performed at Reynolds numbers of 1.0×106 and 1.5×106. During these experiments, several interesting flow characteristics were observed at high angles of attack, mainly that the flow became more sensitive to changes in Reynolds number and the angles of attack of the wing. When the Reynolds number increased from 1×106 to 1.5×106, the upstream progression of the initial point of the main vortex was relatively delayed compared to the sharp-edged delta wing. The experiments also showed that the flow continued to be attached in the apex region up to α = 27º.
Androgens by immunoassay and mass spectrometry in children with 46,XY disorder of sex development
Authors: Oliveira Letícia Ribeiro , Longui Carlos Alberto , Guaragna-Filho Guilherme , Costa José Luiz , Lanaro Rafael , Silva David Antônio , Chiamolera Maria Izabel , de Mello Maricilda Palandi , Morcillo André Moreno , Maciel-Guerra Andrea Trevas , Guerra-Junior Gil 
Published: October 2020

Objective
Steroid measurement is a challenge in pediatric endocrinology. Currently, liquid chromatography with tandem mass spectrometry (LC-MS/MS) is considered a gold standard for this purpose. The aim of this study was to compare both LC-MS/MS and immunoassay (IA) for androgens before and after human recombinant chorionic gonadotropin (rhCG) stimulus in children with 46,XY disorders of sex development (DSD).

Methods
Nineteen patients with 46,XY DSD were evaluated; all of them were prepubertal and non-gonadectomized. Testosterone, dihydrotestosterone (DHT), DHEA and androstenedione were measured by IA and LC-MS/MS before and 7 days after rhCG injection. The correlation between IA and LC-MS/MS was analyzed by the intraclass correlation coefficient (ICC) and Spearman’s rank correlation coefficient (SCC). For concordance analysis the Passing and Bablok (PB) regression and the Bland and Altman (BA) method were used.

Results
Testosterone showed excellent correlation (ICC = 0.960 and SCC = 0.964); DHT showed insignificant and moderate correlations as indicated by ICC (0.222) and SCC (0.631), respectively; DHEA showed moderate correlation (ICC = 0.585 and SCC = 0.716); and androstenedione had poor and moderate correlations in ICC (0.363) and SCC (0.735), respectively. Using the PB method, all hormones showed a linear correlation, but proportional and systematic concordance errors were detected for androstenedione, systematic errors for testosterone and no errors for DHEA and DHT. By the BA method, there was a trend of IA to overestimate testosterone and androstenedione and underestimate DHEA and DHT when compared to LC-MS/MS.

Conclusion
Traditional IA should be replaced by LC-MS/MS for the androgens measurement in prepubertal children whenever is possible.
AdaptingDrosophila melanogasterCell Lines to Serum-Free Culture Conditions
Authors: Luhur Arthur , Mariyappa Daniel , Klueg Kristin M , Buddika Kasun , Tennessen Jason M , Zelhof Andrew C 
Published: October 2020

AbstractSuccessful Drosophila cell culture relies on media containing xenogenic components such as fetal bovine serum to support continuous cell proliferation. Here, we report a serum-free culture condition that supports the growth and proliferation of Drosophila S2R+ and Kc167 cell lines. Importantly, the gradual adaptation of S2R+ and Kc167 cells to a media lacking serum was supported by supplementing the media with adult Drosophila soluble extract, commonly known as fly extract. The utility of these adapted cells lines is largely unchanged. The adapted cells exhibited robust proliferative capacity and a transfection efficiency that was comparable to control cells cultured in serum-containing media. Transcriptomic data indicated that the S2R+ cells cultured with fly extract retain their hemocyte-specific transcriptome profile, and there were no global changes in the transcriptional output of cell signaling pathways. Our metabolome studies indicate that there were very limited metabolic changes. In fact, the cells were likely experiencing less oxidative stress when cultured in the serum-free media supplemented with fly extract. Overall, the Drosophila cell culture conditions reported here consequently provide researchers with an alternative and physiologically relevant resource to address cell biological research questions.