bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tubulin recycling limits cold tolerance
Authors: Li Gabriella , Moore Jeffrey K. 
Published: October 2019

AbstractAlthough cold temperatures have long been used to depolymerize microtubules, how temperature specifically affects the polymerization and depolymerization activities of tubulin proteins and how these lead to changes in microtubule networks in cells has not been established. We investigated these questions in budding yeast, an organism found in diverse environments and therefore predicted to exhibit dynamic microtubules across a broad range of temperatures. We measured the dynamics of GFP-labeled microtubules in living cells and found that lowering the temperature from 37°C to 10°C decreased the rates of both polymerization and depolymerization, decreased the amount of polymer assembled before catastrophes and decreased the frequency of microtubule emergence from nucleation sites. Lowering to 4°C caused rapid loss of almost all microtubule polymer. We provide evidence that these effects on microtubule dynamics may be explained in part by changes in the co-factor-dependent conformational dynamics of tubulin proteins. Ablation of tubulin-binding co-factors further sensitizes cells and their microtubules to low temperatures, and we highlight a specific role for TBCB/Alf1 in microtubule maintenance at low temperatures. Finally, we show that inhibiting the maturation cycle of tubulin by using a point mutant in β-tubulin confers hyper-stable microtubules at low temperatures, rescues the requirement for TBCB/Alf1, and improves the cold tolerance of the yeast. Together, these results reveal an unappreciated step in the tubulin cycle in cells and suggest that this step may be a key limiting factor in the thermal tolerance of organisms.
Loan officer rotation and credit access: evidence from Madagascar
Authors: Sarfo Yaw , Musshoff Oliver , Weber Ron 
Published: October 2019

Purpose
With exclusive data from a commercial microfinance institution (MFI) in Madagascar, the purpose of this paper is to investigate if loan officer rotation (change of loan officer) has an effect on credit access (loan approval) in rural and in urban areas. The authors further analyze how the frequency of loan officer rotation affects credit access in rural and in urban areas.

Design/methodology/approach
The authors apply propensity score matching to compare credit access between loan applicants who experienced loan officer rotation and loan applicants who experienced no loan officer rotation in rural and in urban areas.

Findings
Results show that loan officer rotation has a positive and statistically significant effect on credit access. The authors observe further that loan officer rotation has a different effect on credit access in rural and in urban areas. Whilst rural loan applicants who experienced loan officer rotation are more likely to have credit access, urban loan applicants show no statistically significant effect of loan officer rotation on credit access. For the frequency effect on credit access, the authors observe that one loan officer rotation has a positive and statistically significant effect on credit access whereas results are mixed for two loan officer rotations.

Research limitations/implications
Even though the authors can show that loan officer rotation can improve credit access to loan applicants, especially in rural areas, the conditions in Madagascar are unique. Therefore, results need to be verified in other countries and institutional contexts.

Practical implications
From the perspective of MFI, the authors recommend that the management of MFI needs to provide better tools to loan officers to improve on the evaluation of agricultural loan products or standardize the assessment of agricultural loan products to improve on lending decisions. Further, if applicable, the authors recommend that MFI should consider using credit worthiness assessment procedures which rely less on loan officer’s judgment for loan evaluation, such as automated systems. From the perspective of loan applicants, the authors recommend that loan applicants should request for a change of loan officer if they experience successive loan applications rejection.

Originality/value
To the authors’ knowledge, this paper is the first to provide empirical evidence on the effect and frequency of loan officer rotation on credit access in Sub-Sahara Africa, and Madagascar, in particular.
Factors and their relationships in measuring the progress of open government
Authors: Park Eun G. , Oh Wankeun 
Published: October 2019

Purpose
The purpose of this paper is to examine the main factors influencing government openness, develop a global government openness index (GGOI) for assessing the progress of government openness and investigate how the factors contribute to the advancement of open government by individual countries and country groups by income.

Design/methodology/approach
This study identifies the four factors and adopts them into four variables for making GGOI: accountability (ACC), citizen participation and freedom (CPF), transparency (TRA) and information and communication technology (ICT). To calculate GGOI, panel data for 134 countries from 2006 to 2015 were used.

Findings
GGOI scores constantly improved with an annual growth rate of 2.09 percent. Countries with high ACC values tend to have high TRA scores, resulting in high GGOI scores. While the differences in ACC and TRA were steady over the period, ICT increased the most in all groups. To boost ICT performance as a channel to support other variables, middle-income countries should make further effort for citizens to use ICT capabilities toward enhancing the levels of CPF and TRA.

Research limitations/implications
This study presents a global picture of the advancement of open government and provides insights into specific areas that can be diagonalized.

Practical implications
The GGOI could be used as a useful assessment tool to measure the progress of government openness in countries and implement policies and action plans for improving government openness.

Originality/value
The GGOI covers the areas related to legal, administrative, participatory and technological factors and provides the factors’ inter-relationships for the composition of GGOI.
Cross-border cooperation and urban change in the Trinational Agglomeration Basel
Authors: Fernández Marín Silvia 
Published: October 2019

PurposeThe geographic space of the old Trinational Agglomeration Basel is a complex area where municipalities (and urban systems) belonging to three different countries meet, and part of a paradigmatic scenario where former and recent cross-border cooperation structures and practices are opening opportunities for joint development. The purpose of this paper is to analyse how organisation and spatial relations are being transformed in this context and if there exist barriers, focusing on Weil am Rhein (Germany), Basel (Switzerland) and Saint-Louis and Huningue (France), which converge in the heart of the Agglomeration.Design/methodology/approachThe paper is structured in two parts. The first one is a theoretical exploration of the evolution and extent of cross-border cooperation structures and practices affecting the area. The second one focuses on urban transformation and intertwining resulting from this environment, exploring it through analytical work and cartographies for the 1985–2010 period. In this study, three categories are considered: transport networks, morphology and land use.FindingsResults suggest that cooperation structures are bringing opportunities for the interweaving of neighbouring border urban spaces. However, significant limitations due to regulatory and spatial inheritances and economic constraints, among others, persist. The analysed space continued evidencing barriers and over-simplified areas at the end of the period studied.Originality/valueThe research offers a not-so-frequent, but necessary, perspective of border urban systems as complex scenarios: not only nodes of interaction but also inhabited spaces. It provides insights into border urban development and original cross-border cartography, giving clues on planning in singular environments.
Barriers vs potentials
Authors: Hegazy Iman El-Sayed Hossam , Hegazy Ossama El-Sayed Hossam 
Published: October 2019

Purpose
In 2017, 50 percent of Syrian refugee applications in Egypt were submitted by females. However, a suitable integration strategy for this target group remains obscure since the available approaches focus mainly on male integration. That is due to the assumption that women refugees are mere followers to men who socially and economically dominate the families in the Middle East. Accordingly, the integration of the Syrian women refugees in society, as well as in the market, proceeds spontaneously without clear visions and therefore with delays. The paper aims to discuss this issue.

Design/methodology/approach
To methodologically understand the circumstances of the aforementioned group expert, focused and narrative “episode interviews” have been conducted. Alexandria, Egypt’s second capital, is the research case study as well as the researchers’ hometown. Thus, it allows following a “descriptive comparative analysis” process between the three Alexandrian districts, with different urban fabric: “Al-Nkhil Agamy” gated community, “El-Asafra/Sidi Becher” informal settlement and “New Borg El-Arab” new city.

Findings
Yet, it is unknown what criteria the Syrian women refugees set for choosing their accommodation. Similarly, the obstacles they encounter, especially the ones preventing their integration, are ambiguous. Even their daily life, which might give insights into the barriers they face, due to their status, is unclear. These are the gaps this paper tackles, in addition to the refugees’ immaterial cultural impact in the host society.

Originality/value
Finally, but also importantly, the topic has been seldom researched in Alexandria, in comparison with Cairo. Therefore, this paper aims at qualitatively hearing of the Syrian refugees’ voices in order to enhance their societal interaction and coexistence in Alexandria.
Risk and benefit perceptions related to wine consumption and how it influences consumers’ attitude and behavioural intentions in India
Authors: Gupta Vikas , Sajnani Manohar 
Published: October 2019

Purpose
The purpose of this paper is to discover the numerous risk and benefit perceptions involved in the patrons’ purchase and consumption decisions related to wine in India. It will also recognise and find out the motives behind the consumers’ drinking patterns and attitude towards wine, which affect their overall behavioural intentions (word of mouth and repurchase intentions).

Design/methodology/approach
Data were collected using a structured survey questionnaire from the 375 wine patrons in Delhi. Exploratory factor analysis was used in which the risk (five) and benefit (two) factors related to wine consumption were verified on a factor model using 25 constructs. It was a two-phase process in which the measurement model, with six constructs and 18 measurement items, were measured, trailed by the structural model. A conceptual framework was used to illustrate the relationships amongst the variables and was empirically verified.

Findings
The findings revealed that the risk and benefit perceptions of the wine patrons are not only interlinked but are also accountable for their fluctuations in attitudes. In the factorial analysis, it was discovered that perceived benefit factors, i.e. value for money and convenience, are accountable for positively affecting the attitudes of patrons towards the wines. The results also specify that an increase in benefit perception or decrease in risk perception will positively transform the patrons’ attitude towards wine.

Originality/value
Although a few studies have been done to find out the risk/benefit perceptions of wine consumers in the developed countries (i.e. USA, France, UK, etc.) but this will be the first attempt to find out how the consumption patterns and purchase decisions of wine consumers are affected in developing countries like India. Moreover, it will help the stakeholders to align their wine products as per the needs and demands of the patrons.
Semantic tracking and recommendation using fourfold similarity measure from large scale data using hadoop distributed framework in cloud
Authors: R. Priyadarshini , Tamilselvan Latha , N. Rajendran 
Published: October 2019

Purpose
The purpose of this paper is to propose a fourfold semantic similarity that results in more accuracy compared to the existing literature. The change detection in the URL and the recommendation of the source documents is facilitated by means of a framework in which the fourfold semantic similarity is implied. The latest trends in technology emerge with the continuous growth of resources on the collaborative web. This interactive and collaborative web pretense big challenges in recent technologies like cloud and big data.

Design/methodology/approach
The enormous growth of resources should be accessed in a more efficient manner, and this requires clustering and classification techniques. The resources on the web are described in a more meaningful manner.

Findings
It can be descripted in the form of metadata that is constituted by resource description framework (RDF). Fourfold similarity is proposed compared to three-fold similarity proposed in the existing literature. The fourfold similarity includes the semantic annotation based on the named entity recognition in the user interface, domain-based concept matching and improvised score-based classification of domain-based concept matching based on ontology, sequence-based word sensing algorithm and RDF-based updating of triples. The aggregation of all these similarity measures including the components such as semantic user interface, semantic clustering, and sequence-based classification and semantic recommendation system with RDF updating in change detection.

Research limitations/implications
The existing work suggests that linking resources semantically increases the retrieving and searching ability. Previous literature shows that keywords can be used to retrieve linked information from the article to determine the similarity between the documents using semantic analysis.

Practical implications
These traditional systems also lack in scalability and efficiency issues. The proposed study is to design a model that pulls and prioritizes knowledge-based content from the Hadoop distributed framework. This study also proposes the Hadoop-based pruning system and recommendation system.

Social implications
The pruning system gives an alert about the dynamic changes in the article (virtual document). The changes in the document are automatically updated in the RDF document. This helps in semantic matching and retrieval of the most relevant source with the virtual document.

Originality/value
The recommendation and detection of changes in the blogs are performed semantically using n-triples and automated data structures. User-focussed and choice-based crawling that is proposed in this system also assists the collaborative filtering. Consecutively collaborative filtering recommends the user focussed source documents. The entire clustering and retrieval system is deployed in multi-node Hadoop in the Amazon AWS environment and graphs are plotted and analyzed.
Implications of TQM in firm’s innovation capability
Authors: Jiménez-Jiménez Daniel , Martínez-Costa Micaela , Para-Gonzalez Lorena 
Published: October 2019

Purpose
Over the last few decades, some researchers have analysed the role of total quality management (TQM) as a precursor of innovation. However, the relationship between TQM and organisational innovation remains unclear and contradictory. The purpose of this paper is to provide a framework intended to clarify the complex effect that the implementation of a TQM system has on organisational innovation, where market orientation (MO) and knowledge management (KM) play a mediator role.

Design/methodology/approach
Data in this study come from a survey of 706 Spanish CEOs. The results were analysed employing structural equation modelling to determine how TQM, MO and KM influence innovation.

Findings
The results of the empirical study show that there is a curvilinear effect between TQM and organisational innovation. Both MO and KM perspectives play a mediator role between TQM and innovation.

Practical implications
Managers should be aware that management based on TQM help organisations not only to get higher quality but also to be market oriented and better manage their knowledge; what will help them to develop innovations.

Originality/value
This research sheds light on the question of the relationship between TQM and organisational innovation that has received mixed conclusions in the literature. There is evidence in this research that the relationship between TQM and innovation responds to a curvilinear relationship, where high levels of TQM favour a more than proportionate effect on the development of innovation. It also clarifies the mechanisms by which this effect is produced, with MO and KM as mediator variables.
A new holistic conceptual framework for sustainability oriented hospitality innovation with triple bottom line perspective
Authors: Ozturkoglu Yücel , Sari Ferika Ozer , Saygili Ebru 
Published: October 2019

Purpose
The purpose of this study is to determine the dimensions for “sustainability-oriented hospitality service innovation (SOHSI)” in the context of food and beverage (F&B) industry. For this to be done, the relationship between service innovation dimensions and the triple bottom line (TBL) dimensions (including social, environmental and economic aspects of sustainability) is investigated.

Design/methodology/approach
In this study, primarily a detailed literature review was carried out to specify the dimensions of service innovation in hospitality industry and sustainability as well. Then, fuzzy decision-making trial and evaluation laboratory (DEMATEL), one of the multi-criteria decision-making (MCDM) methods, was used to reveal the causal relationship within these dimensions.

Findings
A framework is presented to help F&B organizations make their innovative services more sustainable. F&B servicing companies should focus especially on “environmental entrepreneurship,” “interior design” and “brand management” dimensions to get benefit underway to gain competitive advantage.

Originality/value
In hospitality industry where competition is increasing every day, it is necessary to create brand-new services or offer renowned services via diversified ways, to step forward from competitors. In this regard, it is important for companies to ensure that every innovative service should be sustainable. Until now, researchers have mostly studied environmental dimension of sustainable service innovation. However, there are no studies evaluating sustainability concept with the TBL approach. Therefore, this study contributes to the field of sustainability in hospitality service innovation.
A learning perspective of supply chain quality management: empirical evidence from US supply chains
Authors: Parast Mahour Mellat 
Published: October 2019

PurposeThis paper aims to examine the relationship between supply chain quality management practices and their impact on supply chain performance. The authors define and operationalize supply chain quality management practices that enhance knowledge creation and learning in a supply chain.Design/methodology/approachData are collected from logistics and supply chain managers in the USA to examine the validity and reliability of the model for supply chain quality.FindingsThe empirical result provides support for the reliability and validity of the proposed model, the constructs used in the model, and the interrelationships among key constructs of supply chain quality. The authors show that trust is the main predictor of supply chain quality practices and supply chain quality performance outcomes. In addition, the findings show that the impact of trust on process improvement is mediated by information sharing, inter-firm trust and information sharing are significant predictors of supply chain satisfaction, and inter-firm trust and process improvement are significant predictors of supply chain performance. Implications of the research for the theory and practice of supply chain management and quality management are presented.Practical implicationsThis study provides important insights into effective implementation of quality management across the supply chain. Supply chain managers should realize that achieving improvement in many supply chain activities such as information sharing or process improvement requires organizations to be engaged in trust-based activities. In that regard, it is important for supply chain managers to be engaged in developing relationships with their supply chain partners that enhance inter-organizational trust.Originality/valueThis is the first study that examines a supply chain quality management model from the learning perspective. The authors validate the supply chain quality framework proposed by Parast (2103) through operationalization of the constructs, development of the relationship among key supply chain quality practices and empirical assessment of the structural model for supply chain quality.
Consistent responses with guselkumab treatment in Asian and non‐Asian patients with psoriasis: An analysis from VOYAGE 1 and VOYAGE 2
Authors: Reich Kristian , Song Michael , Li Shu , Jiang Jingzhi , Youn Sang Woong , Tsai Tsen‐Fang , Choe Yong Beom , Huang Yu‐Huei , Gordon Kenneth B. 
Published: October 2019

AbstractGuselkumab, an interleukin‐23 blocker, was superior to placebo and adalimumab and well‐tolerated in phase 3 psoriasis studies (VOYAGE 1 and VOYAGE 2). This analysis evaluated the consistency of response in the Asian subpopulation in VOYAGE 1 and VOYAGE 2. Study designs were identical through week 24; patients were randomized to guselkumab, placebo, or adalimumab. Investigator's Global Assessment (IGA), Psoriasis Area and Severity Index (PASI), safety, and pharmacokinetic and immunogenicity data from VOYAGE 1 and VOYAGE 2 were pooled and compared by race (Asian, n = 199; non‐Asian, n = 1630). At week 16, treatment differences between guselkumab and placebo were 78.2 (95% confidence interval [CI], 66.9–89.6) and 76.4 (95% CI, 72.7–80.2) percentage points for IGA 0/1 (score of 0 or 1) and 70.1 (95% CI, 60.0–80.1) and 68.5 (95% CI, 64.9–72.2) percentage points for PASI 90 (≥90% improvement) in the Asian and non‐Asian populations, respectively. Treatment differences between guselkumab and adalimumab were 31.1 (95% CI, 17.7–44.6) and 16.1 (95% CI, 11.2–21.0) percentage points for IGA 0/1 and 24.9 (95% CI, 9.4–40.5) and 23.2 (95% CI, 17.7–28.6) percentage points for PASI 90 in the Asian and non‐Asian populations, respectively. Similar results were observed at week 24. Safety was generally similar between populations and among treatment groups. Median serum guselkumab concentrations over time were comparable between the populations. Comparable responses between the Asian and non‐Asian populations in this analysis suggest that the overall efficacy, safety, and the resulting benefit/risk analyses from VOYAGE 1 and VOYAGE 2 are applicable to Asian populations.