bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of changes in sodium and chloride ion transport in the skin
Authors: Hołyńska-Iwan Iga , Szewczyk-Golec Karolina 
Published: October 2020

AbstractThe measurement of electric potential and resistance reflect the transport of sodium and chloride ions which take place in keratinocytes and is associated with skin response to stimuli arising from external and internal environment. The aim of the study was to assess changes in electrical resistance and the transport of chloride and sodium ions, under iso-osmotic conditions and following the use of inhibitors affecting these ions’ transport, namely amiloride (A) and bumetanide (B). The experiment was performed on 104 fragments of rabbit skin, divided into three groups: control (n = 35), A—inhibited sodium transport (n = 33) and B—inhibited chloride transport (n = 36). Measurement of electrical resistance (R) and electrical potential (PD) confirmed tissue viability during the experiment, no statistically significant differences in relation to control conditions were noted. The minimal and maximal PD measured during stimulation confirmed the repeatability of the recorded reactions to the mechanical and mechanical–chemical stimulus for all examined groups. Measurement of PD during stimulation showed differences in the transport of sodium and chloride ions in each of the analyzed groups relative to the control. The statistical analysis of the PD measured in stationary conditions and during mechanical and/or mechanical–chemical stimulation proved that changes in sodium and chloride ion transport constitute the physiological response of keratinocytes to changes in environmental conditions for all applied experimental conditions. Assessment of transdermal ion transport changes may be a useful tool for assessing the skin condition with tendency to pain hyperactivity and hypersensitivity to xenobiotics.
Making sense of human interaction benefits from communicative cues
Authors: Kourtis Dimitrios , Jacob Pierre , Sebanz Natalie , Sperber Dan , Knoblich Günther 
Published: October 2020

AbstractWe investigated whether communicative cues help observers to make sense of human interaction. We recorded EEG from an observer monitoring two individuals who were occasionally communicating with each other via either mutual eye contact and/or pointing gestures, and then jointly attending to the same object or attending to different objects that were placed on a table in front of them. The analyses were focussed on the processing of the interaction outcome (i.e. presence or absence of joint attention) and showed that its interpretation is a two-stage process, as reflected in the N300 and the N400 potentials. The N300 amplitude was reduced when the two individuals shared their focus of attention, which indicates the operation of a cognitive process that involves the relatively fast identification and evaluation of actor–object relationships. On the other hand, the N400 was insensitive to the sharing or distribution of the two individuals’ attentional focus. Interestingly, the N400 was reduced when the interaction outcome was preceded either by mutual eye contact or by a perceived pointing gesture. This shows that observation of communication “opens up” the mind to a wider range of action possibilities and thereby helps to interpret unusual outcomes of social interactions.
Sea ice and atmospheric circulation shape the high-latitude lapse rate feedback
Authors: Feldl Nicole , Po-Chedley Stephen , Singh Hansi K. A. , Hay Stephanie , Kushner Paul J. 
Published: October 2020

AbstractArctic amplification of anthropogenic climate change is widely attributed to the sea-ice albedo feedback, with its attendant increase in absorbed solar radiation, and to the effect of the vertical structure of atmospheric warming on Earth’s outgoing longwave radiation. The latter lapse rate feedback is subject, at high latitudes, to a myriad of local and remote influences whose relative contributions remain unquantified. The distinct controls on the high-latitude lapse rate feedback are here partitioned into “upper” and “lower” contributions originating above and below a characteristic climatological isentropic surface that separates the high-latitude lower troposphere from the rest of the atmosphere. This decomposition clarifies how the positive high-latitude lapse rate feedback over polar oceans arises primarily as an atmospheric response to local sea ice loss and is reduced in subpolar latitudes by an increase in poleward atmospheric energy transport. The separation of the locally driven component of the high-latitude lapse rate feedback further reveals how it and the sea-ice albedo feedback together dominate Arctic amplification as a coupled mechanism operating across the seasonal cycle.
Active magnetocaloric heat pipes provide enhanced specific power of caloric refrigeration
Authors: Maier Lena Maria , Corhan Patrick , Barcza Alexander , Vieyra Hugo A. , Vogel Christian , Koenig Jan D. , Schäfer-Welsen Olaf , Wöllenstein Jürgen , Bartholomé Kilian 
Published: October 2020

AbstractToday almost all refrigeration systems are based on compressors, which often require harmful refrigerants and typically reach 50% of the Carnot efficiency. Caloric cooling systems do not need any detrimental fluids and are expected to reach 60–70% of the Carnot limit. Current caloric systems utilise the active magnetocaloric regeneration principle and are quite cost-intensive, as it is challenging to achieve large cycle frequencies and thus high specific cooling powers with this principle. In this work, we present an alternative solution where the heat transfer from the heat exchangers to the caloric material is predicated on condensation and evaporation of a heat transfer fluid. Using thermal diodes, a directed heat flow is generated. Thereby we were able to build a cooling unit achieving a specific cooling power of 12.5 W g−1 at a cycle frequency of 20 Hz, which is one order of magnitude larger than the state-of-the-art.
Constraint-free wavelength conversion supported by giant optical refraction in a 3D perovskite supercrystal
Authors: Falsi Ludovica , Tartara Luca , Di Mei Fabrizio , Flammini Mariano , Parravicini Jacopo , Pierangeli Davide , Parravicini Gianbattista , Xin Feifei , DiPorto Paolo , Agranat Aharon J. , DelRe Eugenio 
Published: October 2020

AbstractNonlinear response in a material increases with its index of refraction as n4. Commonly, n ~ 1 so that diffraction, dispersion, and chromatic walk-off limit nonlinear scattering. Ferroelectric crystals with a periodic 3D polarization structure overcome some of these constraints through versatile Cherenkov and quasi-phase-matching mechanisms. Three-dimensional self-structuring can also lead to a giant optical refraction. Here, we perform second-harmonic-generation experiments in KTN:Li in conditions of giant broadband refraction. Enhanced response causes wavelength conversion to occur in the form of bulk Cherenkov radiation without diffraction and chromatic walk-off, even in the presence of strong wave-vector mismatch and highly focused beams. The process occurs with a wide spectral acceptance of more than 100 nm in the near infrared spectrum, an ultra-wide angular acceptance of up to ±40∘, with no polarization selectivity, and can be tuned to allow bulk supercontinuum generation. Results pave the way to highly efficient and adaptable nonlinear optical devices with the promise of single-photon-to-single-photon nonlinear optics.
Hand Gestures Facilitate the Acquisition of Novel Phonemic Contrasts When They Appropriately Mimic Target Phonetic Features
Authors: Xi Xiaotong , Li Peng , Baills Florence , Prieto Pilar 
Published: October 2020

PurposeResearch has shown that observing hand gestures mimicking pitch movements or rhythmic patterns can improve the learning of second language (L2) suprasegmental features. However, less is known about the effects of hand gestures on the learning of novel phonemic contrasts. This study examines (a) whether hand gestures mimicking phonetic features can boost L2 segment learning by naive learners and (b) whether a mismatch between the hand gesture form and the target phonetic feature influences the learning effect.MethodFifty Catalan native speakers undertook a short multimodal training session on two types of Mandarin Chinese consonants (plosives and affricates) in either of two conditions: Gesture and No Gesture. In the Gesture condition, a fist-to-open-hand gesture was used to mimic air burst, while the No Gesture condition included no such use of gestures. Crucially, while the hand gesture appropriately mimicked the air burst produced in plosives, this was not the case for affricates. Before and after training, participants were tested on two tasks, namely, the identification task and the imitation task. Participants' speech output was rated by five Chinese native speakers.ResultsThe perception results showed that training with or without gestures yielded similar degrees of improvement for the identification of aspiration contrasts. By contrast, the production results showed that, while training without gestures did not help improve L2 pronunciation, training with gestures improved pronunciation, but only when the given gestures appropriately mimicked the phonetic properties they represented.ConclusionsResults revealed that the efficacy of observing hand gestures on the learning of nonnative phonemes depends on the appropriateness of the form of those gestures relative to the target phonetic features. That is, hand gestures seem to be more useful when they appropriately mimic phonetic features.Supplemental Materialhttps://doi.org/10.23641/asha.13105442
Highly accurate 3D reconstruction based on a precise and robust binocular camera calibration method
Authors: Hu Guoliang , Zhou Zuofeng , Cao Jianzhong , Huang Huimin 
Published: October 2020

The precision of the camera calibration is one of the key factors that affect attitude measurement accuracy in many computer vision tasks. This study proposes a new calibration approach for binocular cameras. Firstly, based on singular value decomposition, the best transformation matrix to the essential matrix is approximated as the initial guess, which is solved in using the Frobenius norm. Secondly, the initial guess is refined through maximum likelihood estimation. A new calculating expression is derived for computing the relative position matrix of the binocular cameras. The Levenberg–Marquardt algorithm is then implemented to refine the initial guess. Large sets of synthesised and real point correspondences were tested to demonstrate the validity of the proposed method. Extensive experiments demonstrated that the proposed method outperforms the state‐of‐the‐art methods. The error rate of the proposed method was 0.5% for the length test and about 1% for the angle test at a range of 1 m. This method can advance three‐dimensional (3D) computer vision one additional step from laboratory environments to real‐world use.
Imaging spectropolarimetry for magnetic field diagnostics in solar prominences
Authors: Di Campli R. , Ramelli R. , Bianda M. , Furno I. , Kumar Dhara S. , Belluzzi L. 
Published: October 2020

Context. Narrowband imaging spectropolarimetry is one of the most powerful tools available to infer information about the intensity and topology of the magnetic fields present in extended plasma structures in the solar atmosphere.
Aims. We describe the instrumental set-up and the observing procedure that we have developed and optimized at the Istituto Ricerche Solari Locarno in order to perform imaging spectropolarimetry. A measurement that highlights the potential of the ensuing observations for magnetic field diagnostics in solar prominences is presented.
Methods. Monochromatic images of solar prominences were obtained by combining a tunable narrowband filter, based on two Fabry-Perot etalons, with a Czerny-Turner spectrograph. Linear and circular polarization were measured at every pixel of the monochromatic image with the Zurich Imaging Polarimeter, ZIMPOL. A wavelength scan was performed across the profile of the considered spectral line. The HAZEL inversion code was applied to the observed Stokes profiles to infer a series of physical properties of the observed structure.
Results. We carried out a spectropolarimetric observation of a prominence, consisting of a set of quasi-monochromatic images across the He I D3 line at 5876 Å in the four Stokes parameters. The map of observed Stokes profiles was inverted with HAZEL, finding magnetic fields with intensities between 15 and 30 G and directed along the spine of the prominence, which is in agreement with the results of previous works.
Estimating the size of X-ray lamppost coronae in active galactic nuclei
Authors: Ursini F. , Dovčiak M. , Zhang W. , Matt G. , Petrucci P.-O. , Done C. 
Published: October 2020

Aims. We report estimates of the X-ray coronal size of active galactic nuclei in the lamppost geometry. In this commonly adopted scenario, the corona is assumed for simplicity to be a point-like X-ray source located on the axis of the accretion disc. However, the corona must intercept a number of optical/UV seed photons from the disc consistent with the observed X-ray flux, which constrains its size.
Methods. We employ a relativistic ray-tracing code, originally developed by Dovčiak and Done, that calculates the size of a Comptonizing lamppost corona illuminated by a standard thin disc. We assume that the disc extends down to the innermost stable circular orbit of a non-spinning or a maximally spinning black hole. We apply this method to a sample of 20 Seyfert 1 galaxies using simultaneous optical/UV and X-ray archival data from XMM-Newton.
Results. At least for the sources accreting below the Eddington limit, we find that a Comptonizing lamppost corona can generally exist, but with constraints on its size and height above the event horizon of the black hole depending on the spin. For a maximally spinning black hole, a solution can almost always be found at any height, while for a non-spinning black hole the height must generally be higher than 5 gravitational radii. This is because, for a given luminosity, a higher spin implies more seed photons illuminating the corona, which is due to a larger and hotter inner disc area. The maximal spin solution is favoured, as it predicts an X-ray photon index in better agreement with the observations.
Bio-additives for CI engines from one-pot alcoholysis reaction of lignocellulosic biomass: an experimental activity
Authors: Raspolli Galletti Anna Maria , Caposciutti Gianluca , Pasini Gianluca , Antonelli Marco , Frigo Stefano 
Published: October 2020

In the recent years the progressive decrease in fossil petroleum resources and gradual deprivation of the environment have attracted increasing interest towards the use of biomass as renewable carbon source for the production of chemicals and transportation fuels. In particular, lignocellulosic biomass represents an abundant and inexpensive renewable resource with high carbon sequestration ability and non-polluting.
In this paper, the valorisation of mixtures made of n-butanol (n-BuOH), butyl levulinate (BL) and dibutyl ether (DBE), in different percentages, as additive fuel for compression ignition (CI) internal combustion engine (ICE) was studied. These mixtures can be directly obtained from the catalytic alcoholysis reaction of the cellulosic fraction of raw and pre-treated lignocellulosic biomasses. Moreover, the possibility to recycle and reutilize the excess alcohol (n-Butanol), during the catalytic alcoholysis reaction, has been considered since it represents an opportunity to reduce the overall costs of the process. Therefore, a blend constituted only by BL and DBE has been also tested. The model mixtures were prepared by using commercial reactants, characterized by compositions analogous to those of the reaction mixtures. These model mixtures were tested as blend with Diesel fuel in a CI-ICE with the measurement of pollutant emission and performance. Results have been compared with those obtained fuelling the engine with a commercial Diesel fuel. As a whole, tests results have evidenced the potentiality of these novel blending mixtures to reduce the emissions of particulate without any significant increase in the other pollutants and negligible changes in engine power and efficiency.
Accuracy of convolutional neural network-based artificial intelligence in diagnosis of gastrointestinal lesions based on endoscopic images: A systematic review and meta-analysis
Authors: Mohan Babu P. , Khan Shahab R. , Kassab Lena L. , Ponnada Suresh , Dulai Parambir S. , Kochhar Gursimran S. 
Published: October 2020

Abstract
Background and study aims Recently, a growing body of evidence has been amassed on evaluation of artificial intelligence (AI) known as deep learning in computer-aided diagnosis of gastrointestinal lesions by means of convolutional neural networks (CNN). We conducted this meta-analysis to study pooled rates of performance for CNN-based AI in diagnosis of gastrointestinal neoplasia from endoscopic images.
Methods Multiple databases were searched (from inception to November 2019) and studies that reported on the performance of AI by means of CNN in the diagnosis of gastrointestinal tumors were selected. A random effects model was used and pooled accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated. Pooled rates were categorized based on the gastrointestinal location of lesion (esophagus, stomach and colorectum).
Results Nineteen studies were included in our final analysis. The pooled accuracy of CNN in esophageal neoplasia was 87.2 % (76–93.6) and NPV was 92.1 % (85.9–95.7); the accuracy in lesions of stomach was 85.8 % (79.8–90.3) and NPV was 92.1 % (85.9–95.7); and in colorectal neoplasia the accuracy was 89.9 % (82–94.7) and NPV was 94.3 % (86.4–97.7).
Conclusions Based on our meta-analysis, CNN-based AI achieved high accuracy in diagnosis of lesions in esophagus, stomach, and colorectum.
Novel approach for Recanalization and Limb Saving Following Acute
Thrombosis of Upper Limb Arteries in Two Neonates After Congenital Heart
Surgery
Authors: Al- Ata Jameel , Abdelmohsen Gaser , Bahaidarah Saud , Alkhushi Naif , Zaher Zaher 
Published: October 2020

IntroductionNeonates with congenital heart disease are at a high risk of vascular thrombosis.
Thrombosis may occur due to vascular injury, increased blood viscosity secondary
to polycythemia associated with congenital cyanotic heart diseases, or stasis of
blood flow associated with low cardiac output (Schmidt B & Andrew M.,
Pediatrics 1995; 96: 939–943. Veldman A et al.,Vasc Health Risk Manag
2008; 4: 1337–1348).
Stenting to prevent esophageal stricture after circumferential endoscopic submucosal dissection: an experimental study
Authors: Martinek Jan , Dolezel Radek , Walterova Bara , Kollar Marek , Juhas Stefan , Juhasova Jana , Vackova Zuzana , Hustak Rastislav , Erben Jakub 
Published: October 2020

Abstract
Background and study aims Circular ESD (CESD) is a treatment option for patients with extensive early esophageal cancer. Its major drawback is the development of a stricture. Stenting may represent an attractive prevention strategy. We designed an experimental study to assess the effect of stents covered with acellular biomatrix (AB) and a drug-eluting stent.
Materials and methods Thirty-five 35 pigs underwent CESD and were randomized into six groups: G1 (control), G2 (SEMS), G3 (SEMS + AB), G4 (SEMS + AB + steroid-eluting layer), G5 (biodegradable stent [BD]), G6 (BD + AB). SEMS were placed alongside the post-CESD defect, fixed and removed after 21 days. The main outcomes were stricture development, severity, and histopathology.
Results Pigs with BD stents (G5, 6) experienced severe inflammation and hypergranulation without biodegradation, therefore, these groups were closed prematurely. Significant strictures developed in 29 of 30 pigs (96.7 %). The most severe stricture developed in G2 and G4 (narrowest diameter (mm) 8.5 ± 3, 3 (G2) and 8.6 ± 2.1 (G4) vs. 17 ± 7.3 (G1) and 13.5 ± 8.3 (G3); P < 0.01. Signs of re-epithelization were present in 67 % and 71 % in G1 and G2 and in 100 % in G3 and G4. The most robust re-epithelization layer was present in G4. The inflammation was the most severe in G1 (mean score 2.3) and least severe in G4 (0.4).
Conclusions Stenting did not effectively prevent development of post-CESD esophageal stricture. SEMS with AB resulted in improved re-epithelization and decreased stricture severity. Steroid-eluting SEMS suppressed inflammation. BD stents seem inappropriate for this indication.
Diagnostik und Behandlung alkoholbezogener Störungen – Versorgerbefragung zur Erarbeitung von Strategien der Leitlinienimplementierung
Authors: Frischknecht Ulrich , Hoffmann Sabine , Steinhauser Alisa , Lindemann Christina , Buchholz Angela , Manthey Jakob , Schulte Bernd , Rehm Jürgen , Kraus Ludwig , Verthein Uwe , Reimer Jens , Kiefer Falk 
Published: October 2020

Zusammenfassung
Ziel der Studie Die Art und Häufigkeit durchgeführter Diagnostik, Kurzintervention und Behandlung bei PatientInnen mit bekanntem problematischen Alkoholkonsum und Alkoholkonsumstörungen durch Berufsgruppen der Gesundheitsversorgung soll erfasst werden. Diese Informationen dienen der Bedarfsabschätzung zur Entwicklung von Strategien zur weiteren Implementierung der S3-Leitlinie „Screening, Diagnose und Behandlung alkoholbezogener Störungen“.
Methodik Schriftliche Befragung von FachärztInnen (hausärztlich allgemeinmedizinisch/internistische, gynäkologische, psychiatrische, pädiatrische, Kinder- und jugendpsychiatrische), PsychotherapeutInnen, SozialarbeiterInnen und Hebammen/Entbindungspflegern in einer Querschnittsstudie in der Modellregion Bremen.
Ergebnisse 34% der PatientInnen mit bekanntem problematischen Alkoholkonsum erhielten eine leitlinienkonforme Diagnostik, 39% eine spezifische Kurzintervention. Von den PatientInnen mit diagnostizierter alkoholbezogener Störung wurde bei 34% eine spezifische Behandlung in eigener Praxis durchgeführt und bei 37% eine Weiterbehandlung anderswo empfohlen. Validierte Instrumente zur Diagnostik alkoholbezogener Störungen fanden selten Anwendung. Kurzinterventionen beinhalteten meist informelle motivierende Gespräche. Als Postakutbehandlungen wurden überwiegend Suchtberatungen und Selbsthilfe und nur selten pharmakologische Rückfallprophylaxe durchgeführt.
Schlussfolgerungen Die Umsetzung strukturierter Diagnostik und Kurzinterventionen, sowie die zielgerichtete Empfehlung pharmakologischer Rückfallprophylaxe und ambulanter Angebote ist für eine leitliniengerechte Versorgung unzureichend. Sie sollten daher Gegenstand von Strategien zur weiteren Leitlinienimplementierung sein.