bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH NAA DAN BAP TERHADAP PERTUMBUHAN CIPLUKAN (Physalis angulate L.) SECARA IN-VITRO
Authors: Amri Assidiqi  , Hasan Basri Jumin  , Ernita  
Published: August 2020

ABSTRACT
The purpose of this study was to determine the interactions and main effects of NAA and BAP hormones on the growth of Ciplukan (Physalis angulata L.). The design used in this study is a complete random design (CRD) which consists of two factors. The first factor is N (NAA) which consists of 4 levels, namely: without treatment, 0.1, 1, and 10 mg / l while the second factor is B (BAP) consisting of 4 levels, namely: without treatment, 0.1, 1 and 10 mg / l. The parameters observed were the percentage of hypocotyl explants forming callus, the age of callus appearing, the number of shoots, and the percentage of hypocotyl explants forming roots. The observational data is then statistically analyzed, if the F count is greater than the F table then proceed with the BNJ test at the 5% level. The results showed that the interaction of NAA and BAP gave a significant effect on the age of callus with the best treatment was the administration of 0.1 mg / l NAA and mg / l BAP 1 (N1B2). The main effect of NAA was significantly on the age of callus with the best treatment of 1 mg / l NAA (N2). The main effect of BAP was significantly on the age of callus with the best treatment 1 mg / l BAP (B2) and the percentage of hypocotyl explants forming roots with the best treatment without BAP administration (B0).
Keywords: Ciplukan, NAA, BAP
Mapping the Space of Chemical Reactions using Attention-Based Neural Networks
Authors: Schwaller Philippe , Probst Daniel , Vaucher Alain C. , Nair Vishnu H , Kreutter David , Laino Teodoro , Reymond Jean-Louis 
Published: August 2020

Organic reactions are usually assigned to classes grouping reactions with similar reagents and mechanisms. Reaction classes facilitate communication of complex concepts and efficient navigation through chemical reaction space. However, the classification process is a tedious task, requiring the identification of the corresponding reaction class template via annotation of the number of molecules in the reactions, the reaction center and the distinction between reactants and reagents. In this work, we show that transformer-based models can infer reaction classes from non-annotated, simple text-based representations of chemical reactions. Our best model reaches a classification accuracy of 98.2%. We also show that the learned representations can be used as reaction fingerprints which capture fine-grained differences between reaction classes better than traditional reaction fingerprints. The unprecedented insights into chemical reaction space enabled by our learned fingerprints is illustrated by an interactive reaction atlas providing visual clustering and similarity searching. Code: https://github.com/rxn4chemistry/rxnfpTutorials: https://rxn4chemistry.github.io/rxnfp/Interactive reaction atlas: https://rxn4chemistry.github.io/rxnfp//tmaps/tmap_ft_10k.html
Faktor Risiko Kejadian Gastritis di Wilayah Kerja Puskesmas Bantilang Tahun 2019
Authors: Nirmalarumsari Chrecencya , Tandipasang Febriani 
Published: August 2020

Gastritis merupakan penyakit urutan pertama terbanyak di wilayah kerja Puskesmas Bantilang di tahun 2017-2018. Faktor yang memicu terjadinya gastritis diantaranya : pola makan, sosial ekonomi, riwayat gastritis keluarga, konsumsi alkohol, stress, dan obat-obatan. Tujuan penelitian mengetahui faktor risiko antara pola makan, sosial ekonomi, stress, dan kebiasaan mengkonsumsi minuman beralkohol terhadap kejadian gastritis. Desain penelitian observasional analitik dengan pendekatan cross sectional. Populasi dalam penelitian ini sebanyak 893 orang, menggunakan rumus slovin dan teknik porposive sampling sehingga diperoleh sampel sebanyak 163 orang. Hasil Penelitian dengan analisa chi-square (Î±=0,05) didapatkan pola makan (P=1,000; OR=1,006), konsumsi alkohol (P=1,000; OR=0,991), Stress (P=0,448; OR=0,986), sosial ekonomi (P=0,390; OR=1,000). Hal ini menunjukkan tidak terdapat hubungan antara 4 variabel independen dengan kejadian gastritis (P>0,005). Terdapat risiko untuk menderita penyakit gastritis meskipun kurang bermakna. Perlunya Pengoptimalan pelaksanaan program di Dinas terkait untuk membangun sikap masyarakat berprilaku hidup sehat melalui penyuluhan penyakit gastritis dan sosialisasi pencegahan terjadinya penyakit gastritis.Â Â Gastritis is the number one disease in the working area of Bantilang Public Health Center in 2017-2018. Factors that trigger gastritis include : diet, socio economic, family gastritis history, alcohol consumption, stress, and drugs. The purpose of the research was to find out the risk factors between diet, socio economic, stress, and habits of consuming alcoholic beverages against gastritis. The research used analytic observational research design with cross sectional approach. The population was 893 people, taken by using the Slovin formula. Purposive sampling technique were used to obtain the sample of 163 people. Research results with chi-square analysis (Î±=0,05) found a diet (P=1,000; OR=1,006), alcohol consumption (P=1,000; OR=0,991), stress (P=0,448; OR=0,986), social economy (P=0,390; OR=1,000) meant there was no correlation between 4 independent variables with the incidence of gastritis (P>0,005). There was a risk of suffering from gastritis even though less significant. It is needed to optimize the implementation of the programs in the health center to build community attitudes towards healthy living through counseling for gastritis and promoting the prevention of gastritis.Â
Edukasi Berpengaruh terhadap Pemberian Stimulasi Perkembangan Anak Usia 12-24 Bulan oleh Ibu di Posyandu Desa Tambakrejo Kabupaten Puworejo
Authors: Khofiyah Nidatul 
Published: August 2020

Pemberian stimulasi merupakan hal penting yang dibutuhan anak dalam masa pertumbuhan dan perkembangannya. Pemantauan pertumbuhan dan perkembangan anak yang dilaksanakan secara tepat dan terarah menjamin tumbuh kembang anak lebih optimal yang menjadikan anak berkualitas, cerdas, bertanggung jawab dan berdaya guna bagi nusa dan bangsa. Tujuan penelitian ini adalah melihat pengaruh edukasi terhadap pemberian stimulasi pada anak usia 12-24 bulan oleh ibu. Penelitian ini menggunakan quasi eksperimen dengan non-equivalent control group design. Sampel penelitian adalah ibu yang memiliki balita usia 12-24 bulan di Posyandu Desa Tambakrejo dengan jumlah sampel 20 responden untuk masing-masing kelompok intervensi dan kelompok kontrol. Instrumen dalam penelitian ini menggunakan SAP dan booklet untuk panduan pemberian edukasi stimulasi dan kuesioner terstruktur untuk data pemberian stimulasi oleh ibu. Analisis menggunakan uji Independen T-Test. Hasil penelitian ini menyatakan bahwa terdapat perbedaan yang signifikan pada perilaku pemberian stimulasi sebelum dan setelah diberikan intervensi edukasi stimulasi pada ibu. Peran kader berpengaruh terhadap pemberian stimulasi oleh ibu kepada anak, sehingga perlu pembinaan untuk kader tentang pemberian stimulasi perkembangan anak yang baik dan terarah melalui pelatihan-pelatihan.Â Provision of stimulation is an important thing that is needed by children in their growth and development. Monitoring the growth and development of children carried out correctly and directed to ensure the development of children is more optimal that makes children of quality, intelligent, responsible and efficient for the homeland and the nation. The purpose of this study is to look at the effect of education on the provision of stimulation in children aged 12-24 months by mothers. This research method uses quasi-experimental with non-equivalent control group design. The study sample was mothers who have children aged 12-24 months in Posyandu Tambakrejo Village with a sample of 20 respondents for each intervention and control groups. The instruments in this study used SAP, booklet and structured questionnaires. The analysis uses the Independent T-Test. The results of this study stated that there were significant differences in the behavior of stimulation before and after the stimulation education intervention was given to the mother. The role of cadres influences the provision of stimulation by the mother to the child, so there is a need for coaching for cadres about providing stimulation of good and directed through training.
Analisis Faktor Determinan yang berhubungan dengan Kepatuhan Rekomendasi Modifikasi Gaya Hidup Pasien Hipertensi
Authors: Qodir Abdul 
Published: August 2020

Penatalaksanaan farmakologis dan non farmakologis dipercaya dapat mengontrol tekanan darah dan mencegah komplikasi, tetapi banyak pasien hipertensi tekanan darahnya tidak terkontrol. Hal tersebut dikarenakan kepatuhan yang buruk dalam melaksanakan rekomendasi gaya hidup. Penelitian ini bertujuan untuk menganalisis determinan faktor yang berhungan dengan kepatuhan melaksanakan rekomendasi modifikasi gaya hidup. Penelitian ini menggunakan metode cross-sectional di pukesmas dinoyo Kota Malang tahun 2019. Teknik pengambilan sampel menggunakan Consecutive Sampling. Kuesioner yang digunakan meliputi : karakteristik demografi, pengetahuan dan rekomendasi mofifikasi gaya hidup pasien hipertensi. Hubungan antara rekomendasi modifikasi gaya hidup dengan variabel independen dianalisis menggunakan uji chi square dan analisis regresi logistik. 140 pasien hipertensi berpartisipasi dalam penelitian ini (60 laki-laki, 80 wanita). Prevalensi kepatuhan adalah 28,6 %. Tingkat pengetahuan berhubungan signifikanÂ dengan kepatuhan melaksanakan rekomendasi gaya hidup (p=0,00). Jenis kelamin, usia, dan tingkat pendidikan tidak mempunyai hubungan signifikan dengan kepatuhan rekomendasi modifikasi gaya hidup (p= 0,06; p=0,21; p=0,87). Pengetahuan mempunyai hubungan yang signifikan dengan kepatuhan rekomendasi modifikasi gaya hidup.Â Management of pharmacological and non-pharmacological is believed to control blood pressure and prevent complications, Â but many hypertensive patients have uncontrolled blood pressure. This is due to poor adherence to recommended lifestyle modifications. This study was aimed to determine the factors associated with adherence to recommended lifestyle modifications of hypertensive patients. A cross-sectional study was conducted in Pukesmas Dinoyo Malang in 2019. Consecutive Sampling was used to select study subjects. The questionnaire included information about demographic characteristics, knowledge, practice of lifestyle-modification measures. Associations between adherence to lifestyle modification and independent variables were analyzed using chi square and multivariate logistic regression analysis. 140 hypertensive patients participated in the study (60 men, 80 women). The prevalence of adherence was 28.6%. The level of knowledge was significant associated with adherence to recommended lifestyle modifications (p = 0.00). Genders , age, and educational level were no significant associated with to recommended lifestyle modifications (p= 0.06; p=0.21; p=0.87). Knowledge was significant associated with adherence to recommended lifestyle modifications of hypertensive patients.
Hubungan Upaya Ibu dalam Mempersiapkan Masa Pubertas dengan Perilaku Seksual Remaja
Authors: Septina Yona 
Published: August 2020

Rendahnya kontrol orang tua terhadap prilaku seksual remaja dapat menyebabkan remaja melakukan prilaku seksual yang beresiko. Penelitian ini bertujuan untuk mengetahui hubungan upaya ibu dalam mempersiapkan masa pubertas dengan perilaku seksual remaja di Desa Sukamantri Kecamatan Sukamantri Kabupaten Ciamis tahun 2016. Penelitian ini merupakan penelitian deskriptif analitik. Populasi dalam penelitian ini adalah seluruh remaja awal usia 12 sampai 15 di Desa Sukamantri Kecamatan Sukamantri Kabupaten Ciamis tahun 2016 sebanyak 1.113 orang. Ukuran sampel yang digunakan adalah sebanyak 92 orang dengan cara random sampling dan menggunakan rumus slovin. Instrumen penelitian menggunakan angket dengan skala Guttman. Uji hipotesis menggunakan uji Chi-Square. Hasil penelitian menunjukan bahwa upaya ibu dalam mempersiapkan masa pubertas di di Desa Sukamantri Kabupaten Ciamis termasuk kategori baik 53,3% dan kurang 46,7%. Perilaku seksual remaja di Desa Sukamantri Kabupaten CiamisÂ termasuk kategori baik 56,5% dan buruk 43,5%. Hubungan upaya ibu mempersiapkan masa pubertas dengan perilaku seksual remaja di Desa Sukamantri Kabupaten Ciamis dengan nilai ï£2 = 80,644 dengan derajat kebebasan (df) 1 dan p-value atau Sig 0,000, dapat disimpulkan bahwa ada hubungan signifikan antara upaya ibu dalam mempersiapkan pubertas dengan dengan prilaku seksual remaja sehingga peran ibu dalam mempersiapkan masa remaja sangat penting untuk dilakukan.Â Low parental control over adolescent sexual behavior can cause teens to engage in risky sexual behavior. This study aimed to determine the correlation of maternal efforts in preparing for puberty and teenage sexual behavior in Sukamantri Village, Sukamantri District, Ciamis Regency in 2016. This study was a descriptive analytic study. The population in this study was all early teens aged 12 to 15 in Sukamantri Village, Sukamantri District, Ciamis Regency in 2016 as many as 1,113 people. The sample was 92 people taken by random sampling and using the Slovin formula. The instrument used a Guttman scale questionnaire. The hypothesis testing used the Chi-Square test. The results showed that maternal efforts in preparing for puberty in Sukamantri Village, Ciamis Regency were 53.3% in the good category and 46.7% less in the lack category. Teenage sexual behavior in Sukamantri Village, Ciamis Regency was 56.5% in the good category and 43.5% in bad category. The correlation ofmaternal efforts to prepare for puberty and adolescent sexual behavior in Sukamantri Village, Ciamis Regency with a value of ï£2 = 80,644 with degrees of freedom (df) 1 and p-value or Sig 0,000. It could be concluded that there was a significant correlation between maternal efforts in preparing puberty with teenage sexual behavior. The role of mothers in preparing for adolescence is very important things to do.
Sensus communis: para entender o espaço acústico em seu ambiente sensorial ressonante
Authors: Machado Irene de Araújo 
Published: August 2020

Como, e com que propósitos, o conceito de espaço acústico emergiu no pensamento de Marshall McLuhan? Quando tentamos encontrar resposta a esta questão, nos deparamos, não com uma
exposição direta, mas com um método especulativo de investigação, denominado de explorações. O objetivo deste ensaio é alcançar as articulações metodológicas e epistemológicas do entendimento construído por McLuhan. Com elas espera-se
compreender os estados de cultura desenvolvidos como sensus communis da era eletrônica.
Palavras-chave
Espaço acústico; ressonância; ambiente; sensório; exploração.
La industria de la música popular en España: los sellos independientes en la era digital
Authors: Albornoz Luis Alfonso , Gallego Juan Ignacio 
Published: August 2020

O artigo apresenta os resultados de uma pesquisa realizada sobre as empresas integrantes do setor independente da música popular na Espanha. Com a finalidade de obter uma fotografia da situação desse setor e analisar suas tendências foi realizada uma enquete on-line entre essas empresas durante o primeiro semestre de 2011. A pesquisa foi dirigida por pesquisadores do Departamento de Jornalismo e Comunicação Audiovisual da Universidade Carlos III de Madri, e teve o apoio da associação espanhola União Fonográfica Independente. O artigo enfoca, principalmente, as diversas atividades e estratégias que as gravadoras e distribuidoras independentes desenvolvem, que incluem uma ativa presença nas novas redes e serviços digitais. Os resultados da pesquisa são apresentados na seguinte ordem: a) perfil das empresas, b) presença internacional, c) estratégias de publicidade e promoção, e d) presença na Internet e nos serviços e redes sociais digitais.

Palavras-chave
Indústria musical. Gravadoras independentes. Internet. Música popular. Espanha.
Language hemispheric dominance analyzed with magnetic resonance DTI: correlation with the Wada test
Authors: Delgado-Fernández Juan , García-Pallero Maria Ángeles , Manzanares-Soler Rafael , Martín-Plasencia Pilar , Blasco Guillermo , Frade-Porto Natalia , Navas-García Marta , Pulido Paloma , Sola Rafael G. , Torres Cristina V. 
Published: August 2020

OBJECTIVE
Language lateralization is a major concern in some patients with pharmacoresistant epilepsy who will face surgery; in these patients, hemispheric dominance testing is essential to avoid further complications. The Wada test is considered the gold standard examination for language localization, but is invasive and requires many human and material resources. Functional MRI and tractography with diffusion tensor imaging (DTI) have demonstrated that they could be useful for locating language in epilepsy surgery, but there is no evidence of the correlation between the Wada test and DTI MRI in language dominance.

METHODS
The authors performed a retrospective review of patients who underwent a Wada test before epilepsy surgery at their institution from 2012 to 2017. The authors retrospectively analyzed fractional anisotropy (FA), number and length of fibers, and volume of the arcuate fasciculus and uncinate fasciculus, comparing dominant and nondominant hemispheres.

RESULTS
Ten patients with temporal lobe epilepsy were reviewed. Statistical analysis showed that the mean FA of the arcuate fasciculus in the dominant hemisphere was higher than in the nondominant hemisphere (0.369 vs 0.329, p = 0.049). Also, the number of fibers in the arcuate fasciculus was greater in the dominant hemisphere (881.5 vs 305.4, p = 0.003). However, no differences were found in the FA of the uncinate fasciculus or number of fibers between hemispheres. The length of fibers of the uncinate fasciculus was longer in the dominant side (74.4 vs 50.1 mm, p = 0.05). Volume in both bundles was more prominent in the dominant hemisphere (12.12 vs 6.48 cm3, p = 0.004, in the arcuate fasciculus, and 8.41 vs 4.16 cm3, p = 0.018, in the uncinate fasciculus). Finally, these parameters were compared in patients in whom the seizure focus was situated in the dominant hemisphere: FA (0.37 vs 0.30, p = 0.05), number of fibers (114.4 vs 315.6, p = 0.014), and volume (12.58 vs 5.88 cm3, p = 0.035) in the arcuate fasciculus were found to be statistically significantly higher in the dominant hemispheres. Linear discriminant analysis of FA, number of fibers, and volume of the arcuate fasciculus showed a correct discrimination in 80% of patients (p = 0.024).

CONCLUSIONS
The analysis of the arcuate fasciculus and other tract bundles by DTI could be a useful tool for language location testing in the preoperative study of patients with refractory epilepsy.
Cost-effectiveness analysis of MR-guided focused ultrasound thalamotomy for tremor-dominant Parkinson’s disease
Authors: Meng Ying , Pople Christopher B. , Kalia Suneil K. , Kalia Lorraine V. , Davidson Benjamin , Bigioni Luca , Li Daniel Zhengze , Suppiah Suganth , Mithani Karim , Scantlebury Nadia , Schwartz Michael L. , Hamani Clement , Lipsman Nir 
Published: August 2020

OBJECTIVE
The development of transcranial MR-guided focused ultrasound (MRgFUS) has revitalized the practice of lesioning procedures in functional neurosurgery. Previous health economic analysis found MRgFUS thalamotomy to be a cost-effective treatment for patients with essential tremor, supporting its reimbursement. With the publication of level I evidence in support of MRgFUS thalamotomy for patients with tremor-dominant Parkinson’s disease (TDPD), the authors performed a health economic comparison between MRgFUS, deep brain stimulation (DBS), and medical therapy.

METHODS
The authors used a decision tree model with rollback analysis and one-factor sensitivity analysis. Literature searches of MRgFUS thalamotomy and unilateral DBS of the ventrointermediate nucleus of the thalamus for TDPD were performed to determine the utility and probabilities for the model. Costs in Canadian dollars (CAD) were derived from the Schedule of Benefits and Fees in Ontario, Canada, and expert opinion on usage.

RESULTS
MRgFUS was associated with an expected cost of $14,831 CAD. Adding MRgFUS to continued medical therapy resulted in an incremental cost-effectiveness ratio of $30,078 per quality-adjusted life year (QALY), which remained cost-effective under various scenarios in the sensitivity analysis. Comparing DBS to MRgFUS, while DBS did not achieve the willingness-to-pay threshold ($56,503 per QALY) in the base case scenario, it did so under several scenarios in the sensitivity analysis.

CONCLUSIONS
MRgFUS thalamotomy is a cost-effective treatment for patients with TDPD, particularly over continued medical therapy. While MRgFUS remains competitive with DBS, the cost-effectiveness advantage is less substantial. These results will help inform the integration of this technology in the healthcare system.
Microendoscopic decompression for lumbosacral foraminal stenosis: a novel surgical strategy based on anatomical considerations using 3D image fusion with MRI/CT
Authors: Murata Shizumasa , Minamide Akihito , Iwasaki Hiroshi , Nakagawa Yukihiro , Hashizume Hiroshi , Yukawa Yasutsugu , Tsutsui Shunji , Takami Masanari , Okada Motohiro , Nagata Keiji , Yoshida Munehito , Schoenfeld Andrew J. , Simpson Andrew K. , Yamada Hiroshi 
Published: August 2020

OBJECTIVEPersistent lumbar foraminal stenosis (LFS) is one of the most common reasons for poor postoperative outcomes and is a major contributor to “failed back surgery syndrome.” The authors describe a new surgical strategy for LFS based on anatomical considerations using 3D image fusion with MRI/CT analysis.METHODSA retrospective review was conducted on 78 consecutive patients surgically treated for LFS at the lumbosacral junction (2013–2017). The location and extent of stenosis, including the narrowest site and associated pathology (bone or soft tissue), were measured using 3D image fusion with MRI/CT. Stenosis was defined as medial intervertebral foraminal (MF; inner edge to pedicle center), lateral intervertebral foraminal (LF; pedicle center to outer edge), or extraforaminal (EF; outside the pedicle). Lumbar (low-back pain, leg pain) and patient satisfaction visual analog scale (VAS) scores and Japanese Orthopaedic Association (JOA) scores were evaluated. Surgical outcome was evaluated 2 years postoperatively.RESULTSMost instances of stenosis existed outside the pedicle’s center (94%), including LF (58%), EF (36%), and MF (6%). In all MF cases, stenosis resulted from soft-tissue structures. The narrowest stenosis sites were localized around the pedicle’s outer border. The areas for sufficient nerve decompression were extended in MF+LF (10%), MF+LF+EF (14%), LF+EF (39%), LF (11%), and EF (26%). No iatrogenic pars interarticularis damage occurred. The JOA score was 14.9 ± 2.6 points preoperatively and 22.4 ± 3.5 points at 2 years postoperatively. The JOA recovery rate was 56.0% ± 18.6%. The VAS score (low-back and leg pain) was significantly improved 2 years postoperatively (p < 0.01). According to patients’ self-assessment of the minimally invasive surgery, 62 (79.5%) chose “surgery met my expectations” at follow-up. Nine patients (11.5%) selected “I did not improve as much as I had hoped but I would undergo the same surgery for the same outcome.”CONCLUSIONSMost LFS existed outside the pedicle’s center and was rarely noted in the pars region. The main regions of stenosis were localized to the pedicle’s outer edge. Considering this anatomical distribution of LFS, the authors recommend that lateral fenestration should be the first priority for foraminal decompression. Other surgical options including foraminotomy, total facetectomy, and hemilaminectomy likely require more bone resections than LFS treatment. The microendoscopic surgery results were very good, indicating that this minimally invasive surgery was suitable for treating this disease.