bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antithrombotic Therapy in Carotid Artery Disease
Authors: Papanikolaou Paraskevi , Antonopoulos Alexios S. , Mastorakou Irene , Angelopoulos Andreas , Kostoula Efthalia , Mystakidi Xara-Vasiliki , Simantiris Spyros , Galiatsatos Nikolaos , Oikonomou Evangelos , Tousoulis Dimitris 
Published: May 2020

:
The management of asymptomatic atherosclerotic carotid artery disease and the role of antithrombotic
therapy is of increasing importance for stroke prevention. Non-invasive imaging of carotid plaques can identify
high-risk plaque features that are associated with the risk of plaque rupture. Carotid plaque necrosis, hemorrhage,
fibrous cap thinning, and the presence of foam cells have all been correlated with the risk of rupture and onset of
neurological symptoms in patients with carotid stenosis. Antiplatelets are currently recommended for patients
with a history of ischemic stroke and/or significant carotid artery stenosis, with aspirin and clopidogrel being the
most widely used and studied agents. The role of dual antiplatelet therapy remains controversial. Moreover, there
is scarce evidence on the role of newer anticoagulant agents in stable patients with carotid artery stenosis. In this
review article, we discuss the pathophysiology of carotid atherosclerosis, the use of non-invasive imaging for
detecting the vulnerable carotid plaque and summarize the existing clinical evidence on the use of antiplatelet and
antithrombotic agents in carotid artery disease.
Anti-Candida Activity of Curcumin: A Systematic Review
Authors: Cheraghipour Kourosh , Ezatpour Behrouz , Masoori Leila , Marzban Abdolrazagh , Sepahvand Asghar , Rouzbahani Arian Karimi , Moridnia Abbas , Khanizadeh Sayyad , Mahmoudvand Hossein 
Published: May 2020

:
Curcumin is one of the important natural compounds that is extracted from turmeric.
This compound and its derivatives have numerous biological properties, including antioxidant,
anticancer, anti-inflammatory, antimicrobial, and healing effects. Extensive research in various
fields has been conducted on turmeric as it is widely used as a food additive. The significant antifungal
activity is one of the major effects of curcumin. In this paper, recent studies on the effects
of different forms of curcumin drug on the candidiasis were systematically examined and discussed.
The data in this study were extracted from the articles and reports published in the Web
of Science, Google Scholar, PubMed, and Scopus databases. After the preliminary investigation,
relevant reports were selected and classified based on the incorporated formulation and purpose
of the study. After a systematic discussion of the data, it was found that the use of medicinal
forms based on nanoparticles can increase the absorption and target the controlled release of curcumin
with a more effective role compared to other formulations. Consequently, it can be concluded
that new methods of modern medicine can be employed to increase the efficacy of natural
pharmaceutical compounds used in the past. In this regard, the present study analyzed the effect
of curcumin against various Candida infections, using the recent data. It was found that applying
a combination of drug formulation or the formulation of curcumin and its derivatives can be an
effective strategy to overcome the medicine resistance in fungal infections, especially candidiasis.
Several Components of the Lebanese Mediterranean Diet and Particular Sociodemographic, Medical and Lifestyle Factors may be Associated with Gastroesophageal Reflux Disease in Adults: A Cross-sectional Study in a Middle Eastern Setting
Authors: Youssef Mary-Joe , Aoun Antoine , Issa Aline , El-Osta Lana , El-Osta Nada , Daham Dany , Doumit Jacqueline 
Published: May 2020

Background:
The prevalence of gastroesophageal reflux disease (GERD) is increasing
worldwide and the related chronic symptoms can be associated with morbidity and poor quality of
life.

Objective:
The objective of this study was to identify foods and beverages consumed by the Lebanese
population, dietary habits, socio-demographic and lifestyle factors, health parameters and perceived
stress, implicated in increasing GERD symptoms.

Methods:
This observational cross-sectional study was carried among Lebanese adults in 2016. A
convenient sample of 264 participants was equally divided into a GERD group and a control group.
Data on socio-demographic characteristics, lifestyle, health status and dietary habits including Lebanese
traditional dishes were collected. The perceived stress scale (PSS) was also used to assess the
participants’ perception of stress. Logistic regression analyses were conducted with GERD symptoms
(presence or absence) being the dependent variable.

Results:
The GERD symptoms were significantly associated with age (-p-value=0.017), family history
of GERD symptoms (-p-value<0.001), smoking (-p-value=0.003) and chronic medical conditions
(-p-value<.001). Regarding the dietary factors, participants who ate three meals or less/day, between
meals and outside homes were 2.5, 2.9 and 2.4 times at a higher risk of experiencing GERD
symptoms than others, respectively. Moreover, the logistic regression model showed that the GERD
symptoms were significantly associated with the consumption of coffee (-p-value=0.037), Lebanese
sweets (-p-value=0.027), fried foods (-p-value=0.031), ‘Labneh’ with garlic (-p-value<0.001), pomegranate
molasses (-p-value=0.011), and tomatoes (-p-value=0.007).

Conclusion:
Some specific lifestyle factors and components of the Lebanese Mediterranean diet
could be associated with GERD symptoms.
Bioactive Compounds for Effective Management of Drug-Resistant Tuberculosis
Authors: Targhotra Monika , Aggarwal Rohan , Chauhan Meenakshi K. 
Published: May 2020

Background:
Tuberculosis is a granulomatous irresistible bacterial sickness brought about by
mycobacterium tuberculosis. The present anti-TB antibiotics are less useful in the treatment of multidrug-resistant (MDR) strains.

Methods:
We underline on distinguishing phytobioactive compounds dependent on customary uses and
testing their concentrates against MDR strains. This will help in future to abbreviate the present
remedial regimens for TB and furthermore for treating HIV-TB co-disease.

Result:
In this article is an endeavor to examine the antimycobacterial and immunomodulatory activity
of the phytobioactive compounds as another option and feature them for additional examination for the
management of drug-resistant tuberculosis.

Conclusion:
This review outlined the procedure for focusing on the tubercle bacilli utilizing bioactive
compounds as the therapeutic vehicle against MDR strains also the synergistic action with currently
available TB medications.
Experimental Investigation of Microstructural Effects in Sn-Pb Solder Accumulated During Ten Years of Service Life
Authors: Werner Marek , Weinberg Kerstin 
Published: May 2020

Aim:
Solder joints of microelectronic devices are subjected to a wide range of loadings.
They affect the microstructural evolution of the alloy. Long term investigations are commonly performed
under thermally accelerated conditions, but are not available for real-life environmental conditions
in literature yet. Therefore, the solder bumps of ten-year-old graphic cards are inspected here.

Objectives:
The primary objective of this study was the investigation of long-term accumulated effects
in solder bumps. We classified the solder concerning its prior electrical functionality and analyzed
theproperties of the microstructure.

Methods:
The image reconstruction is based on component identification, scratch elimination, and image
stitching. Additionally, environmental scanning electron micrographs are employed to investigate
the microstructure of the lead-rich phases.

Results:
Power supplying solder has the widest circularity distribution as a result of anisotropic diffusion
and phase decomposition. On average, a bump with a cross-section of 0.12 mm2 contains 800 Pbrich
phase islands. In the central region of the solder, broad Pb-rich platelets are present. Such platelets
are typically perpendicular to the electric current flow and affected by the mechanical deformation
of the bump. Additional electron-microscopy shows several micro-porous Pb-rich phase islands,
which are induced by an uncalibrated diffusion of tin.

Conclusion:
We found the phase islands’ circularity to be the best indicator for the bulk dynamics.
We conclude that device operation at normal working conditions leads to no hints for functional limitations
at the end of the designed life span.
Online National Health Agency Mask Guidance for the Public in Light of COVID-19: Content Analysis
Authors: Laestadius Linnea , Wang Yang , Ben Taleb Ziyad , Kalan Mohammad Ebrahimi , Cho Young , Manganello Jennifer 
Published: May 2020

Background
The rapid global spread of the coronavirus disease (COVID-19) has compelled national governments to issue guidance on the use of face masks for members of the general public. To date, no work has assessed how this guidance differs across governments.

Objective
This study seeks to contribute to a rational and consistent global response to infectious disease by determining how guidelines differ across nations and regions.

Methods
A content analysis of health agency mask guidelines on agency websites was performed in late March 2020 among 25 countries and regions with large numbers of COVID-19 cases. Countries and regions were assigned across the coding team by language proficiency, with Google Translate used as needed. When available, both the original and English language version of guidance were reviewed.

Results
All examined countries and regions had some form of guidance online, although detail and clarity differed. Although 9 countries and regions recommended surgical, medical, or unspecified masks in public and poorly ventilated places, 16 recommended against people wearing masks in public. There were 2 countries that explicitly recommended against fabric masks. In addition, 12 failed to outline the minimum basic World Health Organization guidance for masks.

Conclusions
Online guidelines for face mask use to prevent COVID-19 in the general public are currently inconsistent across nations and regions, and have been changing often. Efforts to create greater standardization and clarity should be explored in light of the status of COVID-19 as a global pandemic.
PENGARUH TAKARAN MIKORIZA TERHADAP PERTUMBUHAN BIBIT TEH (Camellia sinensis L.) KLON GAMBUNG 7 DI AFDELING PAGILARAN, ANDONGSILI DAN KAYULANDAK
Authors: Wibowo Mohammad 
Published: May 2020

Permasalahan utama yang sering terjadi pada saat pembibitan teh dengan setek adalah lambatnya pembentukan akar yang dapat menyebabkan kematian bibit. Salah satu cara dalam membantu merangsang pembentukan akar dan kalus serta proses penyerapan hara bagi tanaman adalah dengan pemberian agensia hayati Jamur Mikoriza Arbuskular (JMA). Penelitian ini bertujuan untuk mengetahui takaran mikoriza yang paling sesuai untuk pembibitan teh klon Gambung 7 pada ketinggian tempat yang berbeda serta mengetahui pengaruh mikoriza terhadap pertumbuhan bibit teh Gambung 7. Penelitian ini menggunakan rancangan Split-Plot dengan ketinggian sebagai plot utama terdiri dari 3 aras yaitu afdeling Pagilaran (P) dengan ketinggian 980 m dpl, afdeling Andongsili (A) dengan ketinggian 1100 m dpl, dan afdeling Kayulandak (K) dengan Ketinggian 1200 m dpl. Kemudian takaran mikoriza menempati anak petak terdiri dari 4 faktor yaitu dosis 0, 3, 6, 9 gram/polibag. Hasil penelitian menunjukkan terdapat interaksi antara takaran mikoriza dengan ketinggian pada variabel berat kering akar. Nilai berat kering akar tertinggi terdapat pada Afdeling Pagilaran perlakuan kontrol sebesar 1,16 gram, sedangkan hasil paling rendah terdapat pada Afdeling Andongsili perlakuan 9 gram/polibag sebesar 1,02 gram. Tinggi tempat berpengaruh terhadap pertumbuhan bibit Gambung 7 dengan persentase setek hidup tertinggi pada afdeling Kayulandak sebesar 95 %, selanjutnya pada afdeling Pagilaran sebesar 79,75 %, dan afdeling Andongsili sebesar 70,50 %.
A LINGUAGEM COMO INSTRUMENTO DE INCLUSÃO SOCIAL: UMA EXPERIÊNCIA DE ENSINO DO HIP HOP PARA JOVENS E ADULTOS COM DEFICIÊNCIA INTELECTUAL E AUTISMO
Authors: Carvalho Ingrid Rosa , Klein Joyce , Pessoa Daiane Matheus , Chicon José Francisco , Silva de Sá Maria das Graças Carvalho 
Published: May 2020

Objetiva compreender e analisar as diversas manifestações de linguagem produzidas ao longo de uma experiência de ensino do hip hop e seus desdobramentos para o reconhecimento juvenil de jovens e adultos com deficiência intelectual e autismo. Também problematiza as possíveis contribuições dessa experiência para os processos de inclusão social dos envolvidos. Adota a pesquisa qualitativa fundamentada na pesquisa-ação existencial. Foram considerados a partir da análise categorial de conteúdos. A pesquisa evidenciou que o processo de mediação da cultura hip hop fomentou a compreensão sobre as diversas formas e possibilidades de linguagem produzidas com o grupo de modo crítico e criativo, sem desconsiderar as potencialidades, o protagonismo e o reconhecimento da condição juvenil ou adulta dos participantes. Favorece, assim, os processos de inclusão social, ao proporcionar momentos de reconhecimento social e de produção de linguagem, contribuindo com a redução do hiato na interlocução com os demais sujeitos sociais.
Karst environments and disturbance: evaluation of the effects of human activity on grassland and forest naturalness in dolines
Authors: Aguilon Dianne Joy , Vojtkó András , Tölgyesi Csaba , Erdős László , Kiss Péter János , Lőrinczi Gábor , Juhász Orsolya , Frei Kata , Bátori Zoltán 
Published: May 2020

AbstractKarst depressions (dolines) have the potential to act as safe havens for a high diversity of valuable species. We showed that local anthropogenic disturbances play a significant role in determining the naturalness of dolines. We compared the number of specialist species, competitor species, generalist species and species of disturbed habitats between natural and disturbed dolines in two Hungarian karst areas, where different types of anthropogenic disturbances have been shaping the vegetation for centuries. We found that these disturbances have the potential to negatively influence the naturalness of dolines, reducing the number of valuable species, thus affecting the conservation value of dolines. To maintain the naturalness of vegetation in these doline habitats, the populations of ruderal competitors should be eliminated, and sustainable forest management should be adapted. However, there are still open questions about the effects of different disturbances on the naturalness in dolines that need to be answered to determine which conservation strategies will be particularly suitable for valuable species in a warming climate.
PENGEMBANGAN MODEL PEMBELAJARAN OSCAR UNTUK MELATIH PENALARAN SISWA SEKOLAH DASAR DALAM MENYELESAIKAN MASALAH MATEMATIKA
Authors: Holisin Iis , Ainy Chusnal , Wikanta Wiwi 
Published: May 2020

Tujuan penelitian ini adalah untuk mengembangkan model pembelajaran OSCAR yang valid, praktis, dan efektif untuk melatih penalaran siswa dalam menyelesaikan masalah matematika. Metode yang digunakan adalah penelitian pengembangan dengan menggunakan model dari Plomp yang terdiri dari 5 fase, yaitu (1) investigasi awal, (2) desain, (3)realisasi,(4) tes, evaluasi, dan revisi, serta (5) implementasi. Subyek penelitiannya adalah guru matematika dan siswa-siswi kelas V SD tahun ajaran 2017/2018. Penelitian dilaksanakan pada bulan September 2017 sampai April 2018 di SD Muhammadiyah 5, SD Islam Maryam, SD Islam Saroja, dan SD Negeri Sidotopo Wetan I. Semua sekolah berlokasi di Kota Surabaya. Instrumen yang digunakan adalah angket, lembar observasi dan masalah matematika. Selain mengembangkan model pembelajaran, perangkat pembelajaran yang dikembangkan adalah RPP, LKS, dan bahan ajar. Hasil penelitian menunjukkan bahwa model pembelajaran OSCAR yang dikembangkan telah memenuhi kriteria valid, praktis, dan efektif. Hal ini ditunjukkan oleh perolehan nilai rata-rata validitas sebesar 3,32 yang menunjukkan kriteria valid. Aspek kepraktisan ditunjukkan oleh pernyataan para validator bahwa model pembelajaran OSCAR dapat dilaksanakan di lapangan. Aspek efektif ditunjukkan oleh nilai rata-rata keterlaksanaan proses pembelajaran sebesar 3,56 termasuk kategori sangat baik; respon siswa terhadap penerapan model pembelajaran OSCAR 68% menyatakan senang, 78% menganggap baru, seluruh siswa senang terhadap cara guru mengajar; rata-rata kemampuan penalaran siswa mengalami peningkatan, hal ini ditunjukkan oleh besarnya rata-rata nilai N-gain antara 0,35-0,43 dan termasuk kategori sedang.
PENGEMBANGAN MODEL PAIR CHECK UNTUK MENGHINDARI MIND IN CHAOS SISWA KELAS X TERHADAP PEMBELAJARAN MATEMATIKA
Authors: Suciyati Sartika Nenden , Rahmah Yulita S Susti 
Published: May 2020

Tujuan penelitian ini adalah untuk mengembangkan model pembelajaran Pair Check yaitu pembelajaran kooperatif yang merupakan salah satu alternatif yang dapat digunakan dalam pembelajaran matematika, selain untuk meningkatkan motivasi dan hasil belajar, mengoptimalkan pembagian kerja dalam kelompoknya, model ini dikembangkan untuk menghindari terjadinya mind in chaos, suatu kesan negatif yang dibiarkan terjadi sejak mereka masih kecil, yang pada akhirnya hingga dewasa kesan negatif tersebut, yang menyatakan bahwa matematika itu sulit dan menakutkan tetap menetap pada siswa. Metode yang digunakan dalam penelitian ini adalah R & D (Research and Development). Hasil penelitian adalah model Pair Check untuk menghindari Mind In Chaos pada pembelajaran matematika sehingga memberikan pengalaman dan kesan positif siswa terhadap matematika. Desain dan implementasi dari penelitian ini diharapkan menjadi salah satu referensi perkuliahan pada program studi Pendidikan Matematika di Fakultas Keguruan dan Ilmu Pengetahuan, Universitas Mathla’ul Anwar Banten.
PERENCANAAN KEMBALI TEBAL PERKERASAN JALAN BETON BERTULANG MENERUS DENGAN METODE AASHTO 1993 DAN EVALUASI CRACK (STUDI KASUS RUAS JALAN TOL BALARAJA KM. 34+500 – 36+300)
Authors: Pradana Muhammad Fakhruriza , Bethary Rindu Twidi , Rohmah Siti Hadiyati 
Published: May 2020

Cukup banyak proyek pembangunan di Kalimantan Selatan menggunakan bahan geotekstil untuk meningkatkan daya dukung tanah terutama pada tanah lunak (gambut). Interaksi butiran pada permukaan tanah-geotekstil sangat berpengaruh terhadap nilai gaya gesek tanah, interaksi tanah dengan geotekstil bisa saja berbeda tergantung jenis tanahnya. Tujuan penelitian ini yaitu mengetahui nilai kohesi, sudut gesek, dan rasio gesek antar muka tanah gambut dengan geotekstil dalam kondisi tidak terendam air dan kondisi terendam air . Metode yang digunakan adalah metode eksperimen skala laboratorium dengan kondisi benda uji tidak terendam dan terendam air. Geotekstil yang digunakan yaitu woven (HRX250) dan dan non woven (TS600). Hasil pengujian diketahui tanah gambut asli yang berada di Kabupaten Banjar memiliki kohesi (c) 0,017 dan sudut gesek 14,820 untuk kondisi tidak terendam air, sedangkan kondisi terendam air memiliki kohsi (c) 0,029 dan sudut gesek 10,780. Gesek antar muka tanah gambut-geotekstil woven (HRX250) kondisi tidak terendam air 11,590 dengan rasio (d/f) 0,78 dan kondisi terendam air 9,320 dengan rasio (d/f) 0,86. Gesek antar muka tanah gambut-geotekstil non woven (TS600) kondisi tidak terendam air 12,970 dengan rasio (d/f) 0,86 dan kondisi terendam air 9,100 dengan rasio (d/f) 0,84.
Faktor – Faktor yang Berhubungan dengan Kejadian Myalgia pada Nelayan di Desa Batukaras Pangandaran Jawa Barat
Authors: Atthariq Atthariq , Putri Maria Eka 
Published: May 2020

Indonesia merupakan negara kepulauan terbesar ke-4 di dunia dan sekitar 17.000 pulau terdapat 8090 desa pesisir yang tersebar di 300 Kabupaten/Kota pesisir. Sebanyak 67.87 juta bekerja di sektor informal sebagai nelayan atau sekitar 30% penduduk Indonesia. Data hasil penelitian Kementerian Kesehatan pada 2006 mengenai penyakit dan kecelakaan yang terjadi pada nelayan menyebutkan bahwa sejumlah nelayan di Pulau Bungin, Nusa Tenggara Barat menderita nyeri persendian sebesar 57.5%. Tujuan dari penelitian ini adalah diketahuinya hasil analisis faktor-faktor yang berhubungan dengan kejadian myalgia pada nelayan. Penelitian ini merupakan jenis penelitian kuantitatif dengan desain studi cross sectional. Populasi penelitian ini adalah nelayan dengan jumlah sampel 140 responden. Analisis data dilakukan dengan uji Chi Square α 0.05. Hasil penelitian ini diperoleh bahwa variabel yang secara statistik memiliki hubungan yang bermakna dengan kejadian myalgia adalah umur (pvalue=0.019), penghasilan (pvalue=0.004), lama kerja (pvalue=0.024) dan masa kerja (pvalue=0.001). Diperlukan penelitian selanjutnya dengan menambahkan variabel-variabel penelitian yang belum diteliti dengan analisa yang lebih mendalam. Kata Kunci: myalgia; nelayan; otot
Faktor yang Berhubungan dengan Hipertensi pada Ibu Hamil di Kota Makassar
Authors: Basri Hasan , Akbar Rismayanti , Dwinata Indra 
Published: May 2020

Hipertensi mer upakan salah satu masalah kesehatan yang sering muncul selama kehamilan dan dapat menimbulkan komplikasi pada 2-3% kehamilan. Penelitian ini bertujuan mengetahui faktor yang berhubungan dengan kejadian hipertensi pada ibu hamil di wilayah kerja Puskesmas Kassi-kassi Kota Makassar. Penelitian ini merupakan penelitian observasional analitik dengan desain cross sectional. Populasi dalam penelitian ini adalah seluruh ibu hamil di wilayah kerja Puskesmas Kassi-kassi Kota Makassar yang tercatat pada buku register dengan jumlah sampelvsebanyak 138 orang. Metode penarikan sampel yaitu systemtic random sampling serta data di analisis dengan uji chi-square. Pada penelitian ini didapatkan jumlah ibu hamil yang mengalami hipertensi sebanyak 21 orang (15,2%) Selain itu didapatkan ibu hamil yang berada di usia reproduksi tidak aman sebanyak 18 orang (13%), jenjang pendidkan rendah sebanyak 92 orang (66,7%), dukungan keluarga kategori kurang 27 orang (19,6%), kategori stres sebanyak 22 orang (15,9%), penembahan berat badan tidak normal sebanyak 30 orang (21,7%), konsumsi makanan cepat saji sebanyak 28 orang (20,3%). Penelitian ini menunjukkan bahwa ada hubungan antara umur ibu hamil, dukunga keluarga, kondisi stres ibu hamil, penambahan berat badan, serta konsumsi makanan pada ibu hamil (p=0,000) dan tidak ada hubungan antara ibu hamil dengan tingkat pendidikan (p=0,615).
Tingkat Efektivitas Penyembuhan Luka Bakar Derajat IIA dengan Pemberian Madu dan Pemberian Salep Nebacetin pada Tikus Putih (Rattus Norvegicus)
Authors: Hendy Hendy , Lister I Nyoman Erlich 
Published: May 2020

Madu diduga berperan sebagai anti bakteri dan saat ini sudah dimanfaatkan sebagai penanganan korban luka bakar. Penelitian ini bertujuan membandingkan tingkat kesembuhan luka bakar dengan pemberian madu dan nebacetin topikal. Pada penelitian menggunakan 25 ekor tikus jantan Rattus Norvegicus dijadikan subyek penelitian dengan menggunakan eksperimental laboratorik dengan metode pos test only control group design. Tikus dibagi menjadi 5 kelompok secara random yaitu: K1 (Kontrol), K2 (Madu 1x1), K3 (Madu 3x1), K4 (Nebacetin Topikal Gel 5gr 1x1), K5 (Nebacetin Topikal 5gr 3x1) dan dilakukan 15 hari pengamatan. Sebelum perlakuan tikus dibius dengan menggunakan ketamin 1ml yang dicampur dengan NaCl 10ml secara injeksi. Hasil penelitian luka bakar pada kulit tikus menunjukan kesembuhan kulit pada K1, K2, K3, K4, dan K5 adalah K1 sembuh pada hari ke-13, K2 sembuh (keropeng terlepas) pada hari ke-7, K3 sembuh (keropeng terlepas) pada hari ke-10, K4 sembuh (keropeng terlepas) pada hari ke-9, K5 sembuh (keropeng terlepas) pada hari ke-11. Simpulan, madu dapat dijadikan sebagai obat alternatif pada luka bakar sebagai pengganti antibiotik nebacetin topikal, terutama di daerah terpencil. Kata kunci: Luka Bakar, Madu, dan Nebacetin topical 5g