bluuebunny/crossref_metadata_2025_split huggingface dataset:
The lateral supramalleolar flap as solution for lower leg, ankle and foot defects: a surgical case series
Authors: Nsaful Kwesi Okumanin , Gentil Stephane 
Published: November 2020

Introduction. One of the most challenging regions of the body to cover is the lower part of the leg, the ankle, and the foot, especially with the exposure of bones or tendons. Many options for covering soft tissue defects in this area have been proposed. This article describes the lateral supramalleolar flap, which is used for the reconstruction of defects of the lower leg, ankle, heel, and foot. This flap is a surgical technique to salvage the lower extremity due to its large skin paddle and a wide rotation arc. In this case series, patients with lower leg and ankle defects requiring flaps had the lateral supramalleolar flaps performed. This article discusses the overview, technique, and outcomes.Methods. These flaps were performed under spinal anesthesia and tourniquet control.Â The upper limit of the flap was about 8 cm from the popliteal crease, and the lower border was 5 cm from the axis of the ankle joint. The lateral extent of the flap was up to the fibula, contrary to mid-calf. The flap was harvested in the sub-facial plane, and the donor site was grafted.Results. The Flap was generally easy to raise and secure in place at the donor site. Partial necrosis of the flap was reported in one case. The overall donor site morbidity was minimal.Conclusion. The lateral supramalleolar flap is a reliable and useful flap for coverage of the lower third of the leg, ankle, and dorsal foot defects. It is a viable option available to the reconstructive surgeon, especially with the exposure of bones or tendons.Â
Bacterial identification of acne vulgaris
Authors: Sari Lovena , Jusuf Nelva Karmila , Putra Imam Budi 
Published: November 2020

Background:Â Acne vulgaris (AV) is a chronic inflammation of the pilosebaceous unit with clinical polymorphic lesion consist of non-inflammatory (open and closed comedones) and inflammatory lesions (papules, pustules, and nodules) with varying degree of inflammation and depth. Earlier studies showed that other bacteria might also found and played a role in acne pathogenesis besides Cutibacterium acnes (C. acnes).Patients and Methods:Â This descriptive observational study used cross-sectional method. Samples were collected from 40 subjects with AV. We took the samples from non-inflammatory (closed comedones) and inflammatory lesions (pustule) in each subject, followed by Gram staining, aerobic and anaerobic bacterial culture, and bacterial identification. This research has been approved by the Ethical Committee, Faculty of Medicine, University of Sumatera Utara.Results:Â There were 12 bacterial species that were identified from 80 samples. We identified Cutibacterium acnes (21,2%) in anaerobic culture. While in aerobic culture, we identified Staphylococcus epidermidis (47,5%), Staphylococcus hominis (17,5%), Staphylococcus aureus (8,7%), Staphylococcus haemolyticus (8,7%), Leuconostoc mesentroides (6,2%), Micrococcus luteus (3,7%), Kocuria varians (2,5%), Staphylococcus vitulinus (1,2%), Staphylococcus cohnii (1,2%), Staphylococcus arlettae (1,2%) and Dermacoccus nishinomyaensis (1,2%).Conclusion:Â The two most common bacteria in acne vulgaris are Staphylococcus epidermidis and Cutibacterium acnes
Analisis korelasi kadar serum prokalsitonin dengan jumlah leukosit pada penderita dengan kecurigaan sepsis di RSUP Sanglah, Bali, Indonesia
Authors: Dharma Bagus Dwiki Arya , Mulyantari Ni Kadek , Prabawa I Putu Yuda 
Published: November 2020

Background:Â Sepsis is a systemic inflammatory response to infection, where the pathogen or toxin is released into the blood circulation, causing activation of the inflammatory process. Laboratory tests are used to detect inflammatory processes, one of which is procalcitonin. This study aims to determine the correlation between procalcitonin (PCT) serum levels by the leukocytes counts on suspected sepsis patients at Sanglah Hospital in Denpasar.Methods:Â An analytic observational study with the cross-sectional design was conducted among 21 samples by consecutive sampling technique. The population in this study were sepsis patients who were treated at Sanglah Hospital Denpasar during February-June 2016 period. Data were analyzed using SPSS version 17 for Windows.Â Results:Â Â Most of respondents were >35 years old (85.7%), Body Mass Index (BMI) > 20 kg/m2 (76.2%), leucocyte counts < 10.000/Î¼L (42.9%), and PCT levels â‰¤ 0.5 ng/mL (61.9%). There is no significant correlation between white blood cells (WBC) and PCT by Spearman Correlation test (p=0.061; r=0,641).Conclusion:Â The recent findings suggest that there was no significant correlation between PCT serum levels with the leucocytes counts among patients with sepsis.Â Latar Belakang: Sepsis merupakan suatu respon inflamasi sistemik terhadap infeksi, dimana patogen atau toksin dilepaskan ke dalam sirkulasi darah sehingga terjadi aktivasi proses inflamasi. Tes laboratorium yang digunakan untuk mengetahui adanya proses inflamasi salah satunya adalah prokalsitonin (PCT). Penelitian ini bertujuan untuk mengetahui korelasi antara kadar serum prokalsitonin dengan jumlah leukosit pada penderita dengan kecurigaan sepsis di RSUP Sanglah Denpasar.Metode: Penelitian observasional analitik dengan desain tong lintang dilakukan terhadap 21 sampel dengan teknik konsekutif. Populasi dalam penelitian ini adalah pasien sepsis yang dirawat di Rumah Sakit Sanglah Denpasar selama periode Februari-Juni 2016. Data dianalisis menggunakan SPSS versi 17 untuk Windows.Hasil: Sebagian besar responden berusia> 35 tahun (85,7%), Indeks Massa Tubuh (IMT)>20 kg / m2 (76,2%), jumlah leukosit <10.000 / Î¼L (42,9%), dan tingkat PCT â‰¤ 0,5 ng / mL (61,9%). Tidak terdapat korelasi yang bermakna antara sel darah putih (WBC) dan PCT dengan uji Korelasi Spearman (p = 0,061; r = 0,641).Kesimpulan: Hasil penelitian saat ini menunjukkan bahwa tidak terdapat korelasi yang bermakna antara kadar serum PCT dengan jumlah leukosit pada pasien dengan sepsis.
Mean platelet volume count as a risk factor for bloodstream infection in Pediatric Ward Sanglah General Hospital Denpasar, Bali-Indonesia
Authors: Wirantari Ni Putu , Gustawan I Wayan , Utama Made Gede Dwilingga , Arhana Bagus Ngurah Putu , Fatmawati Ni Nengah Dwi , Tarini Ni Made Adi 
Published: November 2020

Background: Mean platelet volume (MPV) is a potentially interesting parameter in predicting bacteremia in patients admitted with suspected community-acquiredÂ infections. The incidence of bacteremia, defined as the presence of viable bacteria in the bloodstream, in patients who were being admitted to hospital. Multiple recent studies have confirmed that low-level bacteremia is more common than previously thought, occurring in 38% to 68% of all pediatric patients with a positive blood culture. The mortality rate is 25%â€“30%, increases to 50% when associated with severe sepsis. The objective of this study is to investigate whether MPV as a risk factor for bloodstream infection.Methods: This was a hospital-based case-control study, review of the medical record from January 2016 until December 2018. We collect age, gender, MPV, platelet and blood culture. We analyze the association between MPV to bloodstream infection.Result: Between January 1st 2016 and December 31st 2018, there were 86 patients with positive blood cultures and 89 negative blood cultures. In the case group, there were 48 (53.9%) male and 41 (46.1%) female subjects, while in the control group there were 63 (73.3%) male and 23 (26.1%) female subjects. The median age for case group was 14 months while the median age for control group was 23 months. From the ROC curve, the optimal cutoff value for MPV was determined as 5.59. The odd ratio determined the relationship between MPV to blood stream infection was 2,26 with 95% CI 1.13-4.52. The adjusted odds ratio was 2.24 95% CI (1.10-4.57). The majority diagnosis was pneumonia (46.1%) in case group then early onset neonatal sepsis (28.1%) and meningitis (7.9%).Conclusion: The MPV â‰¥5.59 is a risk factor for developed bloodstream infection. This result can be used as a cutoff point to initially administered antibiotic to prevent the worse prognosis (sepsis, multiple organ failure, and death).
The association between Body Surface Area (BSA) and vitamin D level among obese adolescent patients in Denpasar, Bali, Indonesia
Authors: Yuliadewi NS Luh Gede , Sidiartha I Gusti Lanang 
Published: November 2020

Background:Â Prevalence of obesity in adolescent in Indonesia is still high. An obese adolescent is likely to stay obese into adulthood and tends to develop into cardiovascular and metabolic diseases. Obese subjects have larger body surface area and should be able to produce more vitamin D from cutaneous synthesis. This study aims to determine the prevalence of obesity in adolescent in Denpasar, determine vitamin D status among obese adolescents and obtained an association between body surface area and vitamin D levels.Methods:Â A descriptive observational study using a cross-sectional approach has been conducted among 51 obese adolescents in Denpasar during May to December 2018. Several variables assessed in this study were age, sex, weight, height, Body Mass Index (BMI), Body Surface Area (BSA), and vitamin D levels. Factors associated with vitamin D levels in obese adolescence were analyzed with appropriate statistical analysis. Data were analyzed using SPSS version 17 for Windows.Â Results:Â From 51 subjects, 32 (62.74%) male and 19 (37.26%) female subjects were enrolled in this study. The mean weight and height of respondents were 89.4Â±9.8 kg and 158.6Â±7.3 cm. In addition, the average Body Mass Index (BMI) and Body Surface Area (BSA) were 33.6Â±3.4 kg/m2 and 2.1Â±0.2 m2. The mean Vitamin D levels was 18.9Â±4.9 ng/mL with 40 subjects (78,4%) were known in a vitamin D deficiency state. There was a significant weak positive association between BSA and vitamin D levels (r=0.32; p=0,002).Conclusion:Â Most obese adolescents were in vitamin D deficiency with a significant weak positive association between BSA and vitamin D levels.Â
Pola pasien anemia yang berkunjung ke Poliklinik Hematologi RSUP Sanglah dari April 2015-April 2017
Authors: Ayu Sintya D Ni Made , Losen Adnyana I Wayan , Suka Aryana IGP 
Published: November 2020

Introduction: Anemia is a clinical condition associated with many causes. Anemia is not a disease, it is a syndrome and generally described as a decreased of red blood cell mass and hemoglobin below the normal level. Based on WHO's criteria, someone can be diagnosed with anemia if their hemoglobin level falls below 130 g/L for men and below 120 g/L for women. Based on a survey made by WHO, about one from every four people in the world suffered from anemia.Aim: The study aims to evaluate the patient arrival pattern to the Hematological Policlinic in RSUP Sanglah Denpasar.Â Method: This is analytic observational research of the anemic patient who came to the Hematological Policlinic in Sanglah General Hospital from April 2015-April 2017.Result: The highest proportion of anemic patient who came to Hematologic Policlinic in Sanglah General Hospital based on age classification are the age group of 15-59 while based on sexes the percentage of the anemic male patient is 44.2%, and the anemic female is 55.8% while 2.9% of that female is currently pregnant.Conclusion: From the causative point of view, the anemic patient in Hematologic Policlinic in Sanglah General Hospital from April 2015 to April 2017 mostly diagnosed with unspecified type while 58.7% of the anemic patient come without another health issues and the other 41.3% have had underlying or accompanying diseases.Introduction: Anemia merupakan suatu kondisi klinis yang diasosiasikan dengan banyak penyebab. Anemia bukan merupakan suatu penyakit melainkan suatu syndrome dan pada umumnya didefinisikan sebagai penurunan sel darah merah dan hemoglobin di bawah nilai normal. Berdasarkan kriteria WHO, seseorang dapat didiagnosis Anemia jika hemoglobinnya berada di bawah 130 g/L untuk laki-laki dan di bawah 120 g/L untuk perempuan. Berdasarkan survey yang dibuat oleh WHO, anemia diderita oleh satu dari empat orang di dunia.Tujuan: Penelitian ini bertujuan untuk mengetahui pola kunjungan pasien ke Poliklinik Hematologi RSUP Sangah Denpasar.Metode: Penelitian ini merupakan suatu penelitian observasional pada pasien anemia yang datang ke poliklinik hematologi RSUP Sanglah dari April 2015-April 2017.Hasil: Berdasarkan penelitian ini dapat dikonklusikan bahwa proporsi tertinggi pasien anemia yang datang ke Poliklinik Hematologi RSUP Sanglah paling banyak adalah dari kelompok umur 15-19 tahun. Sementara itu, berdasarkan kelompok jenis kelamin ditemukan bahwa presentasi pasien anemia perempuan adalah 55,8% dengan 2,9% dari pasien tersebut sedang dalam keadaan hamil sementara pasien anemia laki-laki adalah 44,2%.Simpulan: Dilihat dari penyebabnya pasien anemia yang datang ke Poliklinik Hematologi RSUP Sanglah dari April 2015-April 2017 paling banyak didiagnosis dengan tipe tidak terspesifikasi dengan 58,7% pasien anemia datang tanpa disertai penyakit lain dan 41,3% datang dengan penyakit penyerta.
Korelasi antara persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik pada mahasiswa Fakultas Kedokteran Universitas Mataram
Authors: Widiastuti Ida Ayu Eka , Priyambodo Seto , Buanayuda Gede Wira 
Published: November 2020

Background: Body composition, is one of the factors that play a role in physical fitness. Body composition can be measured by calculating body fat percentage and waist-hip circumference ratio. Excessive body fat, usually will have a negative effect on physical fitness. The purpose of this study was to determine the correlation between body fat percentage and waist-hip circumference ratio with physical fitness.Methods: This study is a descriptive analytic study with a cross sectional design. The subjects were 82 medical students of Universitas Mataram who met the research criteria. Body fat percentage was measured by body composition monitor and physical fitness obtained from maximal oxygen uptake values (VO2max) that were calculated from the results of the Queen College Step Test. Data were analyzed by using the Pearson correlation test.Results: The results showed that the mean of body fat percentage, waist-hip circumference ratio, and VO2max were 28.3 kg/m2, 0.87 cm, and 37.7 ml/kg/minute, respectively. There was a significant correlation between body fat percentage and physical fitness (p = 0.02; r = -0.256) while there was no significant correlation between the waist-hip circumference ratio and physical fitness (p â‰¥ 0.05).Conclusion: The higher the body fat percentage, the lower the level of physical fitness.Â Latar belakang: Komposisi tubuh, merupakan salah satu faktor yang berperan dalam kebugaran fisik. Komposisi tubuh dapat diukur dengan menghitung persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul. Seseorang yang memiliki kadar lemak tubuh yang berlebih, hampir selalu akan memberikan efek negatif terhadap kebugaran fisik. Tujuan penelitian ini adalah mengetahui korelasi antara persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik.Metode: Penelitian ini merupakan penelitian analitik deskriptif dengan desain cross sectional. Subjek penelitian adalah 82 mahasiswi Fakultas Kedokteran Universitas Mataram yang memenuhi kriteria penelitian. Dilakukan pengukuran persentase lemak tubuh dengan body composition monitor, pengukuran lingkar pinggang dan pinggul, dan nilai kebugaran fisik diperoleh dari nilai ambilan oksigen maksimal (VO2max) yang dihitung dari hasil Queen College Step Test. Data dianalisis dengan menggunakan uji korelasi Pearson.Hasil: Hasil penelitian menunjukkan bahwa rerata persentase lemak tubuh, rasio lingkar pinggang-lingkar pinggul, dan VO2max subjek masing-masing adalah 28,3 kg/m2, 0,87 cm, dan 37,7 ml/kg/menit. Terdapat korelasi bermakna antara persentase lemak tubuh dengan kebugaran fisik (p = 0,02; r = -0,256) sementara tidak terdapat korelasi bermakna antara rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik.Simpulan: Semakin tinggi persentase lemak tubuh maka semakin rendah tingkat kebugaran fisiknya.
Efektivitas multi drug therapy pada transmisi morbus hansen transplasental
Authors: Widasmara Dhelya , Basuki Santosa , Florensia Dea , Setyagraha Ade , Prasetyorini Nugrahanti 
Published: November 2020

Introduction:Â The evidence of transplancental transmission of Morbus Hansen (MH) in animal models is a challenge for MH treatment in pregnancy because it brings anxiety for patients and their fetuses.Â Case:Â A 31-year-old pregnant woman, first trimester, came with complaints of reddish numbness rash on her hands since 2 years ago. Dermatological examination showedÂ erythematousÂ plaque, multiple,Â well-defined, irregular borders withÂ hypoaesthesia. There were right and left ulnar nerve enlargement. Acid Fast Bacteria (AFB) fromÂ ear lobesÂ andÂ lesionÂ revealed Bacterial Index +2 and Morphological Index 10%.Â HistopathologicalÂ examination showedÂ grenÂ zone which indicate MH type BL. PatientÂ was diagnosedÂ with MH MultiÂ BasilerÂ (MB) onÂ G3P2002Ab000 and given MDT MHMB. Postpartum IgM and IgGÂ anti-PGL-1Â examination of cord blood and infant blood, alsoÂ PCRÂ examination of cord blood and amnion showed negative results. Histopathological examination found no AFB on the umbilical cord and placenta.Â Conclusion:Â MDT is effective in preventing transplacental transmission of MH from mother to fetus.
Acute fatty liver of pregnancy: a case report
Authors: Mahardika Putu Gede Agus Surya , Prabawa Aditya , Suardana Ketut 
Published: November 2020

Introduction: Acute fatty liver of pregnancy (AFLP) is rare but potentially lethal complication. AFLP characterized by microvascular fatty infiltration of hepatocytes without any inflammation or necrosis.Case Presentation: A 37-year-old multigravida with 29 weeks period of gestation came with chief complains of acute jaundice, nausea, malaise and anorexia since 7 days ago. On examination, her eyes were icteric and her motor power was decreased on both extremities. Abdominal examination showed fetus in cephalic presentation with normal fetal heart rate. There was no opening and effacing of cervix. The ECG result showed prolonged QT interval. She had elevated liver enzyme, decreased renal function, electrolyte imbalance, hypoalbuminemia and hypercholesterolemia. Abdominal ultrasound was within normal limit. Patient was then assessed with differential diagnosed of AFLP, acute hepatitis and HELLP syndrome. She was treated conservatively with ferrous sulfate, high carbohydrate diet, KSR once daily, CDR once daily and Bisoprolol 1.25mg once daily. Â Three months later patient delivered a healthy baby boy via caesarian section due to premature rupture of membrane.Conclusion: Since AFLP is a medical and obstetric emergency, early recognition and prompt treatment improves both maternal and fetal survival.
Diabetes insipidus after suprasellar tumor surgery: case report
Authors: Bakhtiar Yuriz , Arifin Muhamad Thohar , Pratama Adrian , Bunyamin Jacob 
Published: November 2020

Introduction: Diabetes insipidus (DI) is a rare water and electrolyte imbalance with hypovolemic hypernatremia characteristic (1:25.000) however can be potentially fatal if not well-anticipated and managed adequately. Brain tumors, either operated or not, may lead to DI (25%). Based on anatomical location, the suprasellar tumor may cause hypophyseal hormone dysfunction. Sellar region tumors can be classified into hypophyseal (90%) and non-hypophyseal (10%). Non-hypophyseal tumors with neurological deficits are more often causing hypophyseal hormone hyposecretion including DI. Sellar tubercle meningioma is one of the sellar region non-hypophyseal tumors which is often encountered and surgically managed. Worsening symptoms may become the surgical indication e.g. headache and visual disturbance.Â Case: We are reporting two meningioma cases in Salatiga local hospital with almost similar tumor characteristics either size and frontal lobe location. Both cases were managed by similar transcranial tumor excision craniotomy. Their differences were in the presence of neurological manifestations and the degree of hypothalamic compression. One patient developed postoperative DI without thirst thus the clinical manifestation was polyuria which was closely monitored in the intensive ward. We were convinced that the DI incidence was affected by the tumor manifestation and location which can be assessed by computed tomography (CT) scans. Conclusion: The clinicians should anticipate the possibility of post craniotomy DI thus may provide adequate monitoring and management in patients developing postoperative DI.
Electrodeposition of bactericidal and bioactive nano-hydroxyapatite onto electrospun piezoelectric polyvinylidene fluoride scaffolds
Authors: Rodrigues Pedro J. G. , Elias Conceição de M. V. , Viana Bartolomeu C. , de Hollanda Luciana M. , Stocco Thiago D. , de Vasconcellos Luana M. R. , Mello Daphne de C. R. , Santos Francisco E. P. , Marciano Fernanda R. , Lobo Anderson O. 
Published: November 2020

Abstract