bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS JARINGAN KOMUNIKASI UNTUK MENUNJANG KEGIATAN PEMASARAN PADA INDUSTRI KECIL
Authors: Utami Hamidah Nayati 
Published: July 2020

Small industry marketing corelated with comunication process. There are communication process between consumer and producer. The situational factors are support the communication process in group. This situations are comnunication network, comnunication behavior, group cohessivity, size of group. This research aimed to describe communication process and marketing activity on small industry group of ceramics, and to examine the correlation of communication process and marketing activity on small industry group of ceramics. This study was conducted the craftsmen of ceramics at Dau district, Malang Regency. Sample taken with simple random sampling method. Survey and interview technique were implemented among 25 craftsmen. Data was analyzed by using communication network analysis and tau Kendall. The results indicated that the craftsmen had a high level of individual connectedness, a medium level of Individual Integration, but Individual Diversity was low. The level of intensity of craftsman marketing activity was low. The results indicated that of individual connectedness, a medium level of Individual Integration, but Individual Diversity were low were correlated with craftsmen’s activity in promotion, product determining, placement, and pricing.
PENGARUH RELATIONSHIP MARKETING TERHADAP CUSTOMER RETENTION ORIENTATION NASABAH BANK SYARIAH DI KOTA MALANG
Authors: Hasan, MM, Irmayanti 
Published: July 2020

The increasing stringency emulation at banking industry, especially the islamic banking industry, brings the importance of relationship improvement between islamic banks with their costumers. By using relationship marketing as one of the key action to reach costumers’ retention orientation, this research aims to analyze the direct influences, both simultaneously and partially, of variables: belonging, communication, customization, differentiation, personalisation and security, and convinience to costumers’ retention orientation of islamic banks in Malang. The samples are taken from two islamic bank branches in Malang, those are: PT. BRI SYARIAH MALANG BRANCH and PT. BTN SYARIAH MALANG BRANCH. This research applies the quantitative approach, by means of the surveys to take samples from the population, and questionaires to collect the principal data. Number of samples is determined by Slovin’s formula with proportional sampling method to each population: 65 customers of PT. BRI SYARIAH MALANG BRANCH and 35 customers of PT. BTN SYARIAH MALANG BRANCH. Multiple regression analysis is used to predict the relationship between variables. Hypothetic test using F test indicates that the significant simultaneous influence of relationship marketing variables; those are belonging (X1), communication (X2), customization (X3), differentiation (X4), personalization (X5), and security and convenience (X6) to customers’ retention orientation (Y) is acceptable. The test partially indicates that the significant influence of belonging (X1), communication (X2), and customization (X3) to customers’ retention orientation (Y) is acceptable, while the significant influence of differentiation (X4), personalization (X5), and security and convenience (X6) is unacceptable.
STATE OWNED ENTERPRISES (BUMN) REFORM IN INDONESIA: PRIVATIZATION FAILURES
Authors: Efiyanti, MA Alfiana Yuli 
Published: July 2020

It is realized that State Owned Enterprises (BUMN) is one of the most important asset of Indonesia. Those firms are expected to contribute and generate a significant number of revenue. They are also demanded as a public needs provider. However, there are many evidents that the performance of BUMN, that historically heritage from the Dutch colonialist, is not satisfactory. In 1982 when Indonesian economy suffered because of the sharp fall in oil prices, issues regarding the inefficiency of BUMN were widespread due to the lack of their performance. As a result, the government instructed all ministries to increase the productivities and efficiency of BUMN in their departments. Some restructuring and reforming programs including privatization have taken place. However, without any clear objectives, the program was not seriously monitored. Only in mid 1997, when the Asian crises hit Indonesia economy, government needs tool in stabilizing and restructuring the economy. Privatization program then emerged and was not postponed. This report of research presents the failure of privatization program that was adopted during the Asian Crises. It is judged as a failure because the “big bang” action, did not meet both the government written objectives and the theories of privatization.
FUNGSI KONSUMSI RUMAH TANGGA DI INDONESIA (Pendekatan Model Koreksi Kesalahan)
Authors: Sangadji Maryam 
Published: July 2020

Keynesian theory about consumption states that household consumption (C) related positively with present income: the greater income the more consumption. Beside that, interest rate influence negatively toward household consumption, because if the interest rate is low then the loan cost also low, so the factor encourage household to increase it consumption. The results showed that income level related positively with household consumption level. While the interest rate related negatively with consumption level. It means that the greater income encourage the household to increase its consumption. But the increase is not as high as the income level. Then the higher interest rate will cause the household increase its saving, so decrease the consumption. The test by using error correction model (ECM) showed that balance variable of ECT is significant, where for that the household consumption adapted with the income level change and the interest rate at the same period.
PROGRAM TRAINING & DEVELOPMENT BERBASIS SPIRITUALITAS
Authors: Siswanto Siswanto 
Published: July 2020

This paper attempts to explain the role of spirituality in workplace to reach highly organization performance. The currently challenge both profit and non-profit organization is how to develop human resource. That’s so urgent because it’s a valuable asset. Three ways to develop human resource consists of training and development, organization development, and career development. The intent of this paper is to integrate spirituality in training development program. Spirituality in workplace has relationship with attitude and organization behavior dimension (Milliman et.al. 2003). Dimension of organization behavior encompass organization commitment, intention to quit, intrinsic work satisfaction, job involvement, and organization-based self-esteem. The paper concludes that training development based-spirituality will contribute to long term behavior/attitude change.
HIGH TECHNOLOGY CITY OF BANGLORE, KARNATAKA, INDIA
Authors: Efiyanti Alfiana Yuli 
Published: July 2020

Bangalore, sebuah kota yang merupakan ibu kota propinsi Karnataka, salah satu Negara bagian India, telah membuktikan diri mampu mengembangkan diri menjadi kota industri yang yang berteknologi tinggi. Kota ini dikenal sebagai pusat kota yang produktifitasnya sangat tinggi. Industri sotware berkembang pesat sehingga mengundang banyak investor asing, yang pada akhirnya mampu meningkatkan kesejahteraan Negara bagian tersebut. Keberhasilan ini diawali dengan didirikannya sebuah Universitas Teknologi unggulan di Bangalore, pada tahun 1909. Dibarengi dengan kondisi alam yang cukup ideal dan beberapa kebijakan pemerintah termasuk revolusi teknologi, perkembangan Bangalore dapat direkomendasikan sebagai bahan rujukan bagi pembuat kebijakan, terutama bagi pemekaran suatu daerah menjadi sebuah kota berteknologi tinggi.
PELA URGÊNCIA DE VOLTAR A “ANDAR ESPANTADO DE EXISTIR”
Authors: Mferro Marjorie Jorge Rama Ferro 
Published: July 2020

Inspirada pela possibilidade de começar na escola a conscientização das novas gerações, foi planeada uma intervenção para um estudo piloto que teve lugar no ano letivo 2018/19, numa escola secundária (com 3º ciclo) da cidade de Coimbra envolvendo cerca de 900 estudantes (de 1017 inscritos) a propósito da eleição para a Direção da Associação de Estudantes (DAE). Os estudantes foram divididos em dois grandes grupos para reunião de apresentação do projeto de mudança e de reflexão (primeiro o 3º ciclo, estudantes mais novos; de seguida o secundário, estudantes mais velhos e mais ligados aos processos de candidatura e esquemas de campanha).
Da estranheza e rejeição iniciais, os estudantes perceberam as implicações da tarefa de candidatura como procedimento de apresentação de um pensamento para o coletivo, e assumiram a alteração de comportamentos. No novo ano letivo, espera-se que a apresentação de Listas candidatas decorra dentro do padrão de respeito pelos princípios de cidadania e de efetiva apresentação de ideias, e de estratégias de contacto e comunicação com os colegas de escola, potenciais eleitores. A importância do diálogo, do debate de ideias, de pensamento de cidadania construído a partir dos quadros de referência dos sujeitos é a grande conclusão deste projeto.
¿Qué viene después de la pandemia? Un programa de diez puntos para la renovación fundamental
Authors: FEC Foundational Economy Collective 
Published: July 2020

Durante la pandemia mundial por la Covid-19 y ante una inminente crisis derivada de ésta, surgen diversas preocupaciones respecto de las consecuencias económicas que la situación acarreará, así como de la suficiencia de la respuesta de los distintos gobiernos a largo plazo. De esta manera, el Colectivo de Economía Fundamental propone, para el contexto europeo en particular, una serie de puntos esenciales y lecciones para las decisiones de política económica que surjan de esta crisis con el fin de sacar adelante las economías regionales y nacionales una vez que la pandemia sea superada.
Los asesinos invisibles
Authors: Campanella Edoardo 
Published: July 2020

Reseña bibliográfica de:
Frank M. Snowden (2019). Epidemics and Society: From the Black Death to the Present. New Haven: Yale University Press.
Mark Honigsbaum (2019). The Pandemic Century: One Hundred Years of Panic, Hysteria and Hubris. Londres: Hurst Publishers, 2019.
Anticorps anti-chaînes lourdes de myosine : outils d’étude de la régénération musculaire dans l’espèce dinde
Authors: CHEREL Y. , GUIGAND L. , WYERS M. 
Published: July 2020

Cet article fait partie du dossier : Caractérisation des différents types de fibres musculaires dans plusieurs espèces: production et utilisation d’anticorps monoclonaux dirigés contre les chaînes lourdes de myosine rapide IIa et IIb
Fanning the Flames of Inflammaging: Impact of Monocyte Metabolic Reprogramming
Authors: Pence Brandt D. 
Published: July 2020

Abstract
Monocytes are circulating innate immune cells that are functionally dysregulated during aging. However, while metabolic regulation of innate immune cell function is now well-established, only a handful of studies have examined this in the context of aging. In a recent article published in Aging Cell, Saare et al. observe comprehensive metabolic reprogramming of otherwise unstimulated monocytes isolated from older adults. These cells display increased glucose uptake and dysregulation of mitochondrial function, concomitant with activation of signaling pathways contributing to increased inflammation. These findings suggest a mechanism whereby metabolic reprogramming in aged monocytes contributes to chronic low-grade inflammation and open new avenues of investigation into the biological underpinning of inflammaging.
Macrophage Immunometabolism and Inflammaging: Roles of Mitochondrial Dysfunction, Cellular Senescence, CD38, and NAD
Authors: Yarbro Johnathan R. , Emmons Russell S. , Pence Brandt D. 
Published: July 2020

Abstract
Aging is a complex process that involves dysfunction on multiple levels, all of which seem to converge on inflammation. Macrophages are intimately involved in initiating and resolving inflammation, and their dysregulation with age is a primary contributor to inflammaging—a state of chronic, low-grade inflammation that develops during aging. Among the age-related changes that occur to macrophages are a heightened state of basal inflammation and diminished or hyperactive inflammatory responses, which seem to be driven by metabolic-dependent epigenetic changes. In this review article we provide a brief overview of mitochondrial functions and age-related changes that occur to macrophages, with an emphasis on how the inflammaging environment, senescence, and NAD decline can affect their metabolism, promote dysregulation, and contribute to inflammaging and age-related pathologies.
Quiescent stem cell marker genes in glioma gene networks are sufficient to distinguish between normal and glioblastoma (GBM) samples.
Authors: Mukherjee Shradha 
Published: July 2020

Abstract
Grade 4 glioma or GBM has poor prognosis and is the most aggressive grade of glioma. Accurate diagnosis and classification of tumor grade is a critical determinant for development of treatment pathway. Extensive genomic sequencing of gliomas, different cell types, brain tissue regions and advances in bioinformatics algorithms, have presented an opportunity to identify molecular markers that can complement existing histology and imaging methods used to diagnose and classify gliomas. ‘Cancer stem cell theory’ purports that a minor population of stem cells among the heterogeneous population of different cell types in the tumor, drive tumor growth and resistance to therapies. However, characterization of stem cell states in GBM and ability of stem cell state signature genes to serve as diagnostic or prognostic molecular markers are unknown. In this work, two different network construction algorithms, Weighted correlation network analysis (WGCNA) and Multiscale Clustering of Geometric Network (MEGENA), were applied on publicly available glioma, control brain and stem cell gene expression RNA-seq datasets, to identify gene network regulatory modules associated with GBM. Both gene network algorithms identified consensus or equivalent modules, HuAgeGBsplit_18 (WGCNA) and c1_HuAgeGBsplit_32/193 (MEGENA), significantly associated with GBM. Characterization of HuAgeGBsplit_18 (WGCNA) and c1_HuAgeGBsplit_32/193 (MEGENA) modules showed significant enrichment of rodent quiescent stem cell marker genes (GSE70696_QNPbyTAP). A logistic regression model built with eight of these quiescent stem cell marker genes (GSE70696_QNPbyTAP) was sufficient to distinguish between control and GBM samples. This study demonstrates that GBM associated gene regulatory modules are characterized by diagnostic quiescent stem cell marker genes, which may potentially be used clinically as diagnostic markers and therapeutic targets in GBM.
Multidisciplinary Treatment for Colorectal Liver Metastases in Elderly Patients
Authors: Hata Taigo , Mise Yoshihiro , Ono Yoshihiro , Sato Takafumi , Inoue Yosuke , Ito Hiromichi , Takahashi Yu , Yanaga Katsuhiko , Saiura Akio 
Published: July 2020

Abstract
Background: Limited data describe the therapeutic practice and outcomes of colorectal liver metastases (CRLMs) in elderly patients. We aimed to evaluate the impact of age on multidisciplinary treatment for CRLMs. Methods: We reviewed treatment and outcomes for patients in different age groups who underwent initial hepatectomy for CRLMs from 2004 through 2012.Results: We studied 462 patients who were divided into three groups by age: ≤ 64 years (n = 265), 65–74 years (n = 151), and ≥ 75 years (n = 46). The rate of major hepatectomy and incidence of postoperative complications did not differ between groups. Adjuvant chemotherapy was used less in the ≥ 75 -year group (19.6%) than that in the ≤ 64 (54.3%) or 65–74 age group (43.5%). Repeat hepatectomy for liver recurrence was performed less in the ≥ 75 -year group (35%) than in the ≤ 64 (57%) or 65–74 (66%) age group. The 5-year disease-specific survival (DSS) rate of 44.2% in the ≥ 75 -year group was lower than in the ≤ 64 (59.0%) or 65–74 (64.7%) age group. Multivariate analysis revealed age ≥ 75 years was an independent predictor of poor DSS.Conclusions: Liver resection for CRLMs can be performed safely in elderly patients. However, repeat resection for recurrence are performed less frequently in the elderly, which may lead to the poorer disease-specific prognosis.
Factors affecting bone maturation in Chinese girls aged 4-8 years with isolated premature thelarche
Authors: Su Huiping , Su Zhe , Pan Lili , Wang Li , Xu Zhongwei , Peng Gang , Li Xianglei 
Published: July 2020

Abstract
Background: In isolated premature thelarche (IPT) girls, bone age (BA) is considered consistent with chronological age. However, IPT girls confirmed by gonadotropin-releasing hormone (GnRH) stimulation test could show another trend. We analysed BA and possible potentiating factors in girls aged 4-8 years with IPT.Methods: IPT girls aged 4-8 years hospitalized from January 2015 to April 2018 at Shenzhen Children's Hospital were divided into two groups with advanced BA of 2 years as the cut-off. Body mass index (BMI) and hormone levels were the main outcome measures, and regression analysis was used to identify independent risk factors. IPT girls were divided into subgroups separately according to the levels of BMI standard deviation score (SDS), insulin-like growth factor-1 (IGF-1) SDS and dehydroepiandrosterone sulfate (DHEAS) SDS to compare BA.Results: Overall, 423 subjects were classified into the advanced BA (48.7%, n=206) and control groups (51.3%, n=217). The advanced BA group had significantly higher BMI SDS, DHEAS SDS, IGF-1 SDS, androstenedione and serum fasting insulin and significantly lower sex hormone binding globulin (all p<0.001). IGF-1 SDS (OR=1.926, p＜0.001), BMI SDS (OR=1.427, p=0.001) and DHEAS SDS (OR=1.131, p=0.005) were independent risk factors for advanced BA. In the multiple linear regression model, IGF-1 SDS, BMI SDS and DHEAS SDS were the strongest predictors of advanced BA, accounting for 19.3% of the variance. According to BMI, 423 patients were classified into three groups: normal weight (56.03%, n=237 ), overweight (19.15%, n=81) and obesity (24.82%, n=105). The proportion of advanced BA in obesity was significantly higher than that of normal weight and overweight (χ2=18.088, P＜0.001). In a subgroup with normal weight, higher IGF-1 SDS (p=0.009) and DHEAS SDS (p=0.003) affected BA advancement independent of BMI SDS. Conclusions: Girls with IPT confirmed by GnRH stimulation test aged 4-8 years might have significantly advanced BA. Obesity was highly associated with advanced BA. Age-specific serum IGF-1 SDS and DHEAS SDS were risk factors for BA advancement independent of BMI.
Comparative transcriptomic profiling of myxomatous mitral valve disease in the Cavalier King Charles Spaniel
Authors: Markby Greg , Macrae Vicky , Corcoran Brendan , Summers Kim 
Published: July 2020

Abstract
Background. Almost all elderly dogs develop myxomatous mitral valve disease by the end of their life, but the Cavalier King Charles Spaniel (CKCS) has a heightened susceptibility, frequently resulting in death at a young age and suggesting that there is a genetic component to the condition in this breed. Transcriptional profiling can reveal the impact of genetic variation through differences in gene expression levels. The aim of this study was to determine whether expression patterns were different in mitral valves showing myxomatous degeneration from CKCS dogs compared to valves from non-CKCS dogs. Results. Gene expression patterns in three groups of canine valves resulted in distinct separation of normal valves, diseased valves from CKCS and diseased valves from other breeds; the latter were more similar to the normal valves than were the valves from CKCS. Gene expression patterns in diseased valves from CKCS dogs were quite different from those in the valves from other dogs, both affected and normal. Patterns in all diseased valves (from CKCS and other breeds) were also somewhat different from normal non-diseased samples. Analysis of differentially expressed genes showed enrichment in GO terms relating to cardiac development and function and to calcium signalling canonical pathway in the genes down-regulated in the diseased valves from CKCS, compared to normal valves and to diseased valves from other breeds. F2 (prothrombin) (CKCS diseased valves compared to normal) and MEF2C pathway activation (CKCS diseased valves compared to non-CKCS diseased valves) had the strongest association with the gene changes. A large number of genes that were differentially expressed in the CKCS diseased valves compared with normal valves and diseased valves from other breeds were associated with cardiomyocytes including CASQ2, TNNI3 and RYR2. Conclusion. Transcriptomic profiling identified gene expression changes in CKCS diseased valves that were not present in age and disease severity-matched non-CKCS valves. These genes are associated with cardiomyocytes, coagulation and extra-cellular matrix remodelling. Identification of genes that vary in the CKCS will allow exploration of genetic variation to understand the aetiology of the disease in this breed, and ultimately development of breeding strategies to eliminate this disease from the breed.
The influence of Electronic Health Record use on collaboration among medical specialties
Authors: Vos Janita F.J. , Boonstra Albert , Kooistra Arjen , Seelen Marc , Offenbeek Marjolein A.G. van 
Published: July 2020

Abstract
Background: One of the main objectives of Electronic Health Records (EHRs) is to enhance collaboration among healthcare professionals. However, our knowledge of how EHRs actually affect collaborative practices is limited. This study examines how an EHR facilitates and constrains collaboration in five outpatient clinics.Methods: We conducted an embedded case study at five multidisciplinary outpatient clinics of a Dutch hospital that had implemented an organization-wide EHR. Data were collected through semi-structured interviews with representatives of medical specialties, administration, nursing, and management. Documents were then analyzed to contextualize these data. We examined the following six collaborative affordances of EHRs: (1) portability, (2) co-located access, (3) shared overviews, (4) mutual awareness, (5) messaging, and (6) orchestrating.Results: Our findings demonstrate how an EHR will simultaneously both facilitate and constrain collaboration among specialties and disciplines. Affordances that were inscribed in the system for collaboration purposes were not fully actualized in the focal hospital because:(a) The EHR helps health professionals coordinate patient care on an informed basis at any time and in any place but only allows asynchronous patient record use. (b) The comprehensive patient file affords joint clinical decision-making based on shared data, but specialty- and discipline-specific user-interfaces constrain mutual understanding of that data. Moreover, not all relevant information can be easily shared across specialties and outside the hospital. (c) The reduced necessity for face-to-face communication saves time but is experienced as hindering collective responsibility for a smooth workflow. (d) The EHR affords registration at the source and full registration of activities through orders, but the heightened administrative burden for physicians and the strict authorization rules on inputting data constrain the flexible, multidisciplinary collaboration. (e) While the EHR affords a complete overview, information overload occurs due to the parallel generation of individually owned notes and the high frequency of asynchronous communication through messages of varying clinical priority.Conclusions: For the optimal actualization of EHRs’ collaborative affordances in hospitals, coordinated use of these affordances by health professionals is a prerequisite. Such coordinated use requires organizational, technical, and behavioral adaptations. Suggestions for hospital-wide policies to enhance trust in both the EHR and in its coordinated use for effective collaboration are offered.