Abstract PO-120: Differences in health-related quality of life outcomes for Latino versus non- Latino cancer survivors participating in 16-week holistic pilot intervention
Authors: Zamora Corina , Ortiz Alexis , Ramirez Amelie G. , Marin Julissa , Patel Darpan , Serra Monica , Calderon Tim , Gutierrez Bianca , Hertzog Kelseia , Darby Nydia , Lapetoda Angelika , Hughes Daniel C. 
Published: December 2020

Abstract
Introduction: A cancer survivor’s health-related quality of life (HR-QOL) can be conceptualized as the state of the physical, mental, and spiritual aspects that define a human being. Interventions to improve health related quality of life need to address all three of these components. In addition, there may be differences in how interventions can best be applied for different groups that suffer cancer related health disparities such as Latinos, the fastest growing demographic in the U.S. The purpose of this secondary analysis is to understand differences in how a holistic intervention impacts HR-QOL in Latino cancer survivors as compared to non-Latino cancer survivors. The analysis assesses HR-QOL before, during, and at the conclusion of a holistic pilot intervention for 29 adult cancer survivors in San Antonio Texas.
Methodology: Using a retrospective cohort design, we will analyze the association between Latino ethnicity and outcome among participants of a 16-week pilot holistic intervention. The parent study is a pilot feasibility study, consisting of a sample size of 29 adult cancer survivor participants, with any diagnosis of cancer at any stage of treatment. The intervention consists of group yoga-meditation, individualized exercise, diet guidance, and motivational text messages. Participants complete comprehensive assessments of HR-QOL outcomes (body, mind and spirit) using validated instruments and semi-structured interviews at the beginning, mid-way and at the end of 16 weeks. In this analysis we report only the quantitative results and not the interviews. We will report on the differences between Latinos and non- Latinos groups at baseline (week 0), mid-way (week 8) and at post (week 16) on HR- QOL in 2 × 3 analysis of variance (ANOVA). Results: This pilot study is nearly reaching completion of the 16-week active phase of the pilot. Baseline and mid analyses have been completed and currently under analyses. Data was collected on 11 Latino and 18 non-Latino adult survivors. The ‘post’ 16-week assessments are scheduled to be complete by 09/01/2020. We will analyze all the data collected at these three-time assessments reporting on the differences between both groups. Conclusions: Future research must critically review how interventions affect the individuals who participate and how to better meet their needs to improve their health outcomes in an overly strained public health system. With the presence of nearly 17 million cancer survivors in the U.S. today, and with Latino being the largest minority and 18% of the US population, it is increasingly important for survivorship research focused on maximizing HR-QOL for all cancer survivors. In this analysis we report on differences between Latinos/non-Latinos that participated in a 16-week holistic pilot. This data will inform future interventions targeting vulnerable disparate populations, such as Latino cancer survivors; ultimately eliminating unnecessary costs while reducing health disparities gap that continue in this country.
Citation Format: Corina Zamora, Alexis Ortiz, Amelie G. Ramirez, Julissa Marin, Darpan Patel, Monica Serra, Tim Calderon, Bianca Gutierrez, Kelseia Hertzog, Nydia Darby, Angelika Lapetoda, Daniel C. Hughes. Differences in health-related quality of life outcomes for Latino versus non- Latino cancer survivors participating in 16-week holistic pilot intervention [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-120.