bluuebunny/crossref_metadata_2025_split huggingface dataset:
Keeping It Cool: Much Orbit Migration, yet Little Heating, in the Galactic Disk
Authors: Frankel Neige , Sanders Jason , Ting (丁源森) Yuan-Sen , Rix Hans-Walter 
Published: June 2020

Abstract
A star in the Milky Way’s disk can now be at a Galactocentric radius quite distant from its birth radius for two reasons: either its orbit has become eccentric through radial heating, which increases its radial action J

R
(“blurring”), or merely its angular momentum L

z
has changed and thereby its guiding radius (“churning”). We know that radial orbit migration is strong in the Galactic low-α disk and set out to quantify the relative importance of these two effects, by devising and applying a parameterized model (

) for the distribution

in the stellar disk. This model describes the orbit evolution for stars of age τ and metallicity

, presuming that coeval stars were initially born on (near-)circular orbits, and with a unique

at a given birth angular momentum and age. We fit this model to APOGEE red clump stars, accounting for the complex selection function of the survey. The best-fit model implies changes of angular momentum of

and changes of radial action as

at 8 kpc. This suggests that the secular orbit evolution of the disk is dominated by diffusion in angular momentum, with radial heating being an order of magnitude lower.
Intestinal parasitic infections in children under five in the Central Hospital of Nampula, Northern Mozambique
Authors: Ferreira Filipa Santana , Pereira Filomena da Luz Martins , Martins Maria do Rosário Oliveira 
Published: June 2020

Introduction: Intestinal parasites are known to cause infection in humans worldwide, with higher prevalence in low- and middle- incoming countries. Children are greatly affected leading to malnutrition and subsequently to physical and cognitive development impairment. Despite the scale and importance of this issue, there are few studies conducted in Mozambique concerning parasitic intestinal infections in hospitalized children. To our knowledge this is the first published report with data on this subject from Northern Mozambique.
Methodology: A cross-sectional study was conducted in 2012 and 2013 in 831 children, attending the Central Hospital of Nampula in Northern Mozambique. One single stool sample was obtained from each child. Socio-demographic and clinical data were also obtained. Parasitological analysis of feces was performed through direct examination and Ritchie concentration technique and Giardia duodenalis antigen detection by rapid immunochromatographic test. Modified Ziehl-Neelsen staining was used for coccidia detection.
Results: The global prevalence of pathogenic intestinal parasites was 31.6%. G. duodenalis (23.9%) was by far the most prevalent parasite followed by Strongyloides stercoralis (4.1%) and Cryptosporidium sp. (3.4%). Intestinal parasites were more frequent in older children (p = 0.005; aOR = 1.025).
Conclusions: This work is one of the few published studies reporting intestinal parasites infection in hospitalized children. The percentage of children affected with G. duodenalis is higher than found in other studies in the African region. This highlights the need of particular attention being given to this intestinal protozoan and its resistance to water treatment, as well as to environmental health and personal hygiene.
The accuracy of tuberculous meningitis diagnostic tests using Bayesian latent class analysis
Authors: Le Huy Ngoc , Sriplung Hutcha , Chongsuvivatwong Virasakdi , Nguyen Nhung Viet , Nguyen Tri Huu 
Published: June 2020

Introduction: Tuberculous meningitis (TBM) is the most dangerous form of tuberculosis with high mortality and disability rates. However, the delayed diagnostic process is often due to the absence of the gold standard tests leading to a lack of information about the sensitivity and specificity of diagnostic tests. This study aims to estimate the prevalence of TBM and determine the performance of four diagnostic procedures: the mycobacteria growth culture test, Gene Xpert assay, and analysis of protein levels and leukocyte count taken from cerebrospinal fluid.
Methodology: We used a Bayesian latent class analysis to estimate the prevalence of TBM with 95% credible interval (CI), and the specificity and sensitivity of the four diagnostic procedures. The area under the receiver operating characteristic curve (AUC) of the cerebrospinal protein levels and leukocyte count were also compared and estimated using different thresholds.
Results: A total of 1,213 patients suspected of having TBM were included. The estimated TBM prevalence was 34.8 % (95% CI: 28.8 – 41.3). The sensitivity of culture test and Gene Xpert assay was 62.7% (95% CI: 52.5 – 74.0), and 57.5% (95% CI: 51.0 – 64.0), and the specificity of Gene-Xpert was 95. 9% (95% CI: 92.0 – 99.8). The AUC for leukocyte count was 76.0%, and for protein level was 73.4%.
Conclusions: This study provided better information about the performance of four routine diagnostic tests and the prevalence of TBM which can enhance disease control and improve treatment outcomes.
Proteomics analysis of important molecules in serum from meningitic piglets caused by Streptococcus suis serotype 2
Authors: Jiang Hexiang , Liu Jianan , Wu Tong , Liu Mengmeng , Sun Qiang , Wang Junjie , Zhu Rining , Qu Guanggang , Li Shuguang , Liu Hongtao , Lei Liancheng 
Published: June 2020

Introduction: Streptococcus suis serotype 2 (SS2) is an important zoonotic pathogen that causes meningitis in China. This study’s aim was comparative analysis of serum proteomics from meningitis and non-meningitis piglets.
Methodology: SS2 meningitis and non-meningitis piglet models were established. The serum samples were collected and analyzed by label-free LC-MS/MS proteomics technology. Differentially expressed proteins (DEPs) from serum were screened out by comparing the meningitis group and non-meningitis group to the healthy group (M/C; N/C), respectively. And then, globally and comparative analysis of DEPs in “M/C” and “N/C” in serum were performed using bioinformatics method. Finally, we comparatively analyzed the serum and cerebrospinal fluid proteomics in piglets that lived with meningitis.
Results: We obtained 316 and 191 DEPs from “M/C” and “N/C” which classification visualizations were established. 157 DEPs were common in both groups and 159 DEPs were unique to the “M/C”. These DEPs and the signaling pathways which they participated in were visualized. Moreover, some DEPs which participated in multiple pathways were discovered and the interaction between 159 DEPs was also mapped. 39 common DEPs were also screened out in serum and cerebrospinal fluid during meningitis, and signaling pathways associated with these DEPs were further visualized.
Conclusions: DEPs in “M/C” and “N/C” were comparatively analyzed and the similarities and differences of these DEPS which were involved in signal pathways were summarized. Moreover, several important molecules were screened out.
Epidemiological and clinical characteristics of COVID-19 patients in Nantong, China
Authors: Lu Renfei , Qin Jianru , Wu Yan , Wang Jian , Huang Shengyong , Tian Lijun , Zhang Tao , Wu Xiuming , Huang Songping , Jin Xia , Zhang Chiyu 
Published: June 2020

Introduction: COVID-19 is a newly emerging life-threatening respiratory disease caused by a newly identified coronavirus SARS-CoV-2.
Methodology: We included 28 COVID-19 patients admitted to Nantong Third Hospital from January 23 to February 26, 2020. SARS-CoV-2 infection was confirmed using real-time RT-PCR. The demographic, epidemiological, clinical, laboratory parameters were obtained from each patient.
Results: The vast majority (71.4%) of confirmed COVID-19 patients were brought in from outside of the city, and all others had contact history with these confirmed cases. The median age of patients was 50 years old and half had underlying diseases. The most common symptoms at the onset of illness were fever (96.4%), cough (67.9%), and chilly (28.6%), and 75.0% patients had two or more symptoms. Increased erythrocyte sedimentation rate, serum ferritin and C-reactive protein levels, and reduced absolute counts of total lymphocytes and T lymphocyte subsets were observed among the patients. The vast majority (85.7%) of patients showed bilateral or unilateral pneumonia, and three symptomatic patients and one asymptomatic case did not show abnormalities in their CT image. Among the 28 admitted patients, 24 were discharged as of February 26, 2020, with an average hospital stay of 14.96 (±4.27) days, which was not significantly associated with the interval between the onset of symptoms and admission.
Conclusions: In the absence of specific antiviral drugs or a vaccine, quarantine or isolation is the most effective intervention strategy for preventing the spread of the virus. Adequate supportive medical care is crucial for good prognosis of COVID-19 patients.
Débats de 1932 sur la sexualité féminine et enjeux pour la cure
Authors: Rossi Patricia 
Published: June 2020

Dans une lettre à Freud de mai 1932, Ferenczi évoque un cycle de conférences avec de « vifs débats sur le complexe féminin de castration et l’ envie de pénis ». Non sans provocation, il interpelle Freud. Nous en repérons les résonances de transferts de travail dans son Journal clinique . Trois psychanalystes, Lilian Rotter, Alice Balint et Fanny Hann-Kende sont intervenues. En allant à leur rencontre, nous découvrons l’originalité de leur recherche fondée sur les théories non phallocentrées et la créativité de l’école hongroise affranchie du dogme.
Stratégies de l’inconscient dans l’œuvre d’art
Authors: Landa Eva 
Published: June 2020

Les bijoux contemporains, forme d’art qui renverse les codes traditionnels de la haute joaillerie, intéressent d’autant plus la psychanalyse qu’ils laissent entrevoir de façon particulière le travail de l’artiste en tant que « stratège de l’inconscient ». L’analyse du vœu inconscient qui s’exprime dans les œuvres de quatre créatrices permet d’en dégager différentes déclinaisons du féminin.
Le véritable premier amour de l’adolescent Sigmund Freud
Authors: Kamieniak Jean-Pierre 
Published: June 2020

Si Freud a délibérément effacé toute trace de l’identité de son véritable premier amour, attribuant après coup dans une lettre à Martha ce statut à l’ingénue Gisela et contribuant ainsi à la légende du héros, une étude attentive des lettres retrouvées de l’adolescent puis du fiancé Freud, associées aux événements de son histoire, fait de cet « aveu » fallacieux un voile pudique jeté sur ce profond émoi qui l’avait préalablement saisi pour une autre jeune fille au pseudonyme d’Ichtyosaura, lui permettant aussi d’offrir en retour à Martha cette âme innocente qu’il exigeait d’elle.
Le rôle des entrepreneurs politiques dans les processus de transfert
Authors: Larrouqué Damien 
Published: June 2020

Si les notions d’« entrepreneur politique » et de « transfert » sont stabilisées sur le plan conceptuel, il est rare de les appréhender de concert. La littérature présume que l’entrepreneur politique participe à la diffusion des innovations en matière de politiques publiques, sans pour autant que les modalités de son investissement dans un tel processus n’aient été systématiquement analysées. Sur la base d’une typologie construite autour de quatre idéal-types, cet article se propose d’étudier en perspective comparée le rôle joué par les entrepreneurs politiques dans le transfert du projet socio-éducatif One Laptop Per Child en Amérique latine durant la seconde moitié des années 2000.
La marginalisation du référendum communal en France depuis 2003
Authors: Prémat Christophe 
Published: June 2020

Les discussions portant sur le projet de l’aéroport Notre-Dame-des-Landes en 2016, sur le référendum d’initiative citoyenne pendant la mobilisation des Gilets jaunes en 2018-2019 et sur le lancement du référendum d’initiative partagée en juin 2019 contre la privatisation des aéroports parisiens ont relancé le débat sur la combinaison du système représentatif avec des procédures de démocratie directe au niveau local. Pourtant, il existe depuis le début des années 2000 des dispositifs censés favoriser la participation des habitants à la vie politique locale. Cette note de recherche examine ainsi la pratique du référendum communal depuis la réforme de 2003 introduisant le référendum décisionnel afin de comprendre si celui-ci fonctionne comme un élément de résolution de conflits locaux ou s’il est davantage un indicateur des problématiques spécifiques de certains territoires. L’analyse de données récoltées sur ces dispositifs entre 2003 et 2019 permet d’en dégager les facteurs explicatifs.
« À quoi t’as rêvé ? »
Authors: Robichon Caroline 
Published: June 2020

À partir d’exemples de situations rencontrées dans l’exercice des fonctions de formatrice, cet article évoque une posture professionnelle qui s’appuie sur la considération de l’autre comme un autre soi-même. Le postulat se fonde sur l’idée que c’est grâce à l’instauration d’une relation à parité d’estime que le passage, la transmission entre le formateur et la personne en formation se réalise, lui permettant de construire son sujet professionnel. Via un accompagnement maïeuticien, ce sujet professionnel en devenir est invité à se souvenir de son rêve initial, « ce qu’il fout là », pour se forger une éthique et se penser.
Le rapt de la formation continue
Authors: Rouzel Joseph 
Published: June 2020

À travers l’exemple d’un centre de formation continue, l’auteur fait apparaître le démantèlement de la transmission des métiers du travail social, mais aussi du droit à se former pour les professionnels. Comment faire pour résister et continuer à donner sens à la clinique au-delà des normes gestionnaires ?
Faux et usage de faux : la difficile émancipation de Saint-Sernin (xie-xiie siècles)
Authors: Pradalié Gérard 
Published: June 2020

La grande affaire de la Réforme grégorienne à Toulouse (XIe-XIIe siècles) est la lutte de l’église Saint-Sernin pour obtenir son émancipation et celle du bourg vis-à-vis de l’évêque et de la cité. Dans cette lutte qui dure trois quarts de siècle, tous les coups – tous les faux – semblent permis.
Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome
Authors: Matikainen Sampsa , Nyman Tuula A. , Cypryk Wojciech 
Published: June 2020

Abstract
Inflammasomes are multiprotein complexes of the innate immune system that orchestrate development of inflammation by activating the secretion of proinflammatory cytokines, IL-1β and IL-18. The LPS of Gram-negative bacteria have been shown to activate a novel, noncanonical inflammasome by directly binding in the cytosol to human caspase-4 and mouse caspase-11. Activation of noncanonical inflammasome exerts two major effects: it activates the NLRP3–caspase-1–mediated processing and secretion of IL-1β and IL-18 and induces the inflammatory cell death, pyroptosis, via gasdermin D. This previously unexpected cytosolic LPS sensing of the innate immune system provides critical hints for host response to Gram-negative bacterial infections and development of different inflammatory diseases. However, many of its molecular regulatory mechanisms are yet to be discovered. In this review, we provide comprehensive analysis of current understanding of intracellular LPS detection and pyroptosis via noncanonical inflammasome and discuss the recently proposed mechanisms of its function and regulation.
Outcomes of patients with Severe Acute Respiratory Infections (SARI) admitted to the intensive care unit: Results from the Egyptian Surveillance Study 2010-2014
Authors: Abu Elhassan Usama E. , Mohamed Sherif A.A. , Rizk Magda S. , Sherif Mai , El-Harras Mohamed 
Published: June 2020

Background: Few data exist for respiratory viral infections in Egyptian patients. We describe the outcomes of hospitalized Egyptian patients with severe acute respiratory infections (SARI) admitted to the ICU. Methods: A prospective study in which all hospitalized patients meeting the WHO case definition for SARI and admitted to the ICU, during the period 2010–2014, were enrolled. Samples were tested using RT-PCR for influenza A, B, respiratory syncytial virus (RSV), human metapneumovirus (hMPV), parainfluenza virus, adenovirus, bocavirus, enterovirus, and rhinovirus. Data were analyzed to study the clinical features of SARI-ICU patients and which pathogens are related to severe outcomes. Associated comorbidities were evaluated using Charlson Age-Comorbidity Index (CACI). Results: Of 1075 patients with SARI, 219 (20.3%) were admitted to the ICU. The highest rates were reported for RSV (37%). SARI-ICU patients had higher rates of hospital stay, pneumonia, respiratory failure, ARDS, and mortality. Multivariate logistic regression analysis identified associated respiratory disorders (p=0.001), radiological abnormalities (p=0.023), and longer hospital stay (p=0.005) as risk factors for severe outcomes. Conclusions: This surveillance study showed that 20% of hospitalized Egyptian patients with viral SARI needed ICU admission. SARI-ICU patients had higher rates of hospital stay, pneumonia, respiratory failure, ARDS, and mortality. Higher comorbidity index scores, radiological abnormalities, and longer hospital stay are risk factors for severe outcomes in SARI-ICU patients in our locality.
Health-related quality of life in patients with breast cancer surgery and undergoing chemotherapy in Ahmednagar district
Authors: Kshirsagar Aishwarya Sunil , Wani Surendra Kiran 
Published: June 2020

Background:
Breast cancer in India it varies from as low as 5 per 100,000 female populations per year in rural areas to 30 per 100,000 female populations per year in urban areas. Medical treatments of surgery, chemotherapy etc. for cancer usually precipitates with serious adverse effects affecting overall quality of life in physical, psychological and social aspects.

Objective of the Study:
To evaluate health related quality of life in patients who had been followed up after the breast cancer surgery for chemotherapy at our hospital.

Methods:
Quality of life was documented using European Organization of Research and Treatment for Cancer Quality of life Questionnaire-Cancer 30 (EORTC QOL-C30) and European Organization of Research and Treatment for Cancer Quality of life Questionnaire-Breast 23 (EORTC QOL-BR23).

Results:
After analysis of EORTC QOL-C30 questionnaire, participants had maximum affection of cognitive, social and physical functions and reported high levels of pain, fatigue and insomnia. Domains of EORTC QOL-BR23, the such as worry about self body image, sexual dysfunction, upset by hair loss, systemic therapy side effects, breast and arm symptom were reported by maximum participants. Various domains of quality of life were maximally affected in patients of breast cancer surgery undergoing chemotherapy. Health care professionals in the field of Oncology should address the above mentioned domains of quality of life in Indian patients with breast cancer surgery undergoing chemotherapy.

Conclusion:
Comprehensive cancer management plan should include psychological counseling, emotional support, physiotherapy care for pain and other musculoskeletal problems etc. along with medical treatment of patients with breast cancer.
La construcción de textos argumentativos en los escolares primarios.
Authors: Ana Margarita Díaz Solano  , Noraida Fonseca Pita  , Yusleidys Rodríguez Aguilar.  
Published: June 2020

Todas las actividades de construcción textual están encaminadas a favorecer el desarrollo del pensamiento y el lenguaje. Las dirigidas al texto argumentativo, además, tienen como finalidad adiestrar a los escolares en la búsqueda de razones o argumentos que sustenten la veracidad o conformidad de la idea o tesis. El maestro es el encargado de dirigir tan difícil tarea. Para lograr este propósito, es necesario que esté preparado para conducir con éxito la construcción de este tipo de texto. En el presente artículo se proponen actividades dirigidas a la construcción de textos argumentativos en los escolares primarios.
Prinsip-Prinsip Filsafat Pendidikan Kristen
Authors: Tety Tety , Wiraatmadja Soeparwata 
Published: June 2020

Tety and Soeparwata Wiraatmadja, The Philosophy Principles of Christian Educating. This paper discusses the principles of the philosophy of Christian education. The writer describes in the paper some important issues related to the principles of the philosophy of Christian education including the review of the Christian education of theological and philosophical aspects, then epistemology and axiology, the philosophy and purpose of Christian education. The final part of this paper the author describes some of the principles of the philosophy of Christian education. Tety dan Soeparwata Wiraatmadja, Prinsip-Prinsip Filsafat Pendidikan Kristen. Makalah ini membahas tentang prinsip-prinsip filsafat pendidikan Kristen. Penulis menguraikan dalam makalah beberapa hal penting terkait prinsip-prinsip filsafat pendidikan Kristen diantaranya adalah tinjauan terhadap pendidikan Kristen dari aspek teologis dan filsafatnya, lalu epistemologi dan aksiologi, filsafat dan tujuan pendidikan Kristen. Bagian akhir dari makalah ini penulis menguraikan beberapa prinsip filsafat pendidikan Kristen.
Signifikansi Pendidikan Anak Dalam Perspektif Alkitab
Authors: Wenas Maria Lidya , Darmawan I Putu Ayub 
Published: June 2020

Maria Lidya Wenas & I Putu Ayub Darmawan, Significance Children Education in Biblical Perspective. Education of children is important in human life. Formulation of the problem in this research is how the Bible perpsektif about children's education? The purpose of this study is to outline perpsektif Bible about children's education. Types of research in this paper is the qualitative research literature. The object of this study is a biblical perspective on the education of children. In this study, researchers conducted a literature study to be able to explore and understand the biblical view of children's education. In this study, the authors sought feedback from a grasp of Hebrew and Greek. This is to avoid the use of verses in Hebrew and Greek avoid deviations. From this study showed that (1) Education of children as the planting of faith; (2) Education of children as a process of knowledge transfer; (3) the child's education as a process of value investment. Maria Lidya Wenas &I Putu Ayub Darmawan, Signifikansi Pendidikan Anak Dalam Perspektif Alkitab. Pendidikan anak merupakan hal yang penting dalam kehidupan manusia. Rumusan masalah dalam penelitian ini adalah bagaimana perpsektif Alkitab tentang pendidikan anak? Tujuan dari penelitian ini adalah memaparkan perpsektif Alkitab tentang pendidikan anak. Jenis penelitan dalam karya tulis ini adalah penelitian kualitatif studi pustaka. Objek penelitian ini adalah perspektif Alkitab tentang pendidikan anak. Dalam penelitian ini, peneliti melakukan studi literatur untuk dapat menggali dan memahami pandangan Alkitab tentang pendidikan anak. Dalam penelitian ini penulis meminta masukan dari seorang yang memahami tentang Bahasa Ibrani dan Bahasa Yunani. Hal tersebut dilakukan agar penggunaan ayat-ayat dalam Bahasa Ibrani dan Bahasa Yunani tidak terjadi penyimpangan. Dari penelitian ini diperoleh hasil yaitu (1) Pendidikan anak sebagai proses penanaman iman; (2) Pendidikan anak sebagai proses transfer pengetahuan; (3) pendidikan anak sebagai proses penanaman nilai.