bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bacteriological profile and antibiogram of cancer patients admitted in intensive care unit of a tertiary care cancer hospital in central Kerala
Authors: Ramakrishnan Sanjana , Radhakrishnan Sourabh , Cyriac Sonu Lazar 
Published: November 2020

Background: Opportunistic bacterial infections remain a serious morbidity among cancer patients. This study was aimed to determine the bacteriological and antibiotic profile of cancer patients admitted to the ICU of a tertiary care centre.Methods: Cross sectional study was done among cancer patients admitted in the Oncology neutropenic ICU during the period from August 2017 to July 2019. All patients admitted with a proven diagnosis of cancer for whom at least one bacterial culture was sent from any site were included in the study. Laboratory on culture reports were obtained from patient files and analysed.Results: A total of 278 samples from 256 patients (60±11.6 years) were analysed. Among the 111/278 positive cultures, 29 were blood samples and 1 was a pleural fluid sample. Gram negative organisms were 62.1% with Escherichia coli (25, 36.2%) as prevalent. Among the 37.8% gram positives, Staphylococcus aureus (18. 42.8%) was prevalent. Most of the E. coli strains showed highest resistance to ceftazidime (96%) and highest sensitivity to amikacin. The commonest gram-positive organism, Staphylococcus species were 100 % sensitive to vancomycin and linezolid and 100 % resistance to penicillin. Conclusions: E. coli (gram negative) showed highest resistance to ceftazidime and sensitivity to amikacin. S. aureus (gram positive) was sensitive to vancomycin and linezolid and resistance to penicillin. An antibiogram for cancer patients helps the clinician to initiate an appropriate empirical antibiotic therapy to reduce mortality and morbidity.
Comparison of local versus spinal anaesthesia in inguinal hernia repair
Authors: Bhardwaj Suraj , Sharma Shuchi , Bhardwaj Vatika , Lal Roshan 
Published: November 2020

Background: Inguinal hernioplasty remain one of the most commonly performed operations worldwide. Local anaesthesia can be a preferred method in day-case hernia surgeries. Present study was thus conducted to determine whether local anaesthetic technique is an acceptable alternative to spinal anaesthesia for hernia repair, especially with regards to operative conditions, postoperative pain relief and complications.Methods: This was a prospective randomized single blinded clinical study consisting of sixty patients conducted after the ethical committee clearance. The patients posted for tension free lichtenstein elective hernioplasty were allocated to either of two groups, group A (n=30) were given local anaesthesia and patients in group B (n=30) were given spinal anaesthesia. The operative and postoperative pain sore using visual analogue scale, duration of surgery and any other complications were recorded.Results: There was no demographic difference between the two groups. Time taken in local anesthesia was higher than spinal anesthesia. Intraoperative pain was higher in local anesthesia than spinal anesthesia. There was no difference in post-operative pain scores (p>0.05). Post-operative complications were more in spinal anesthesia group e.g. urinary retention, headache, etc.Conclusions: Local anesthesia can be another good choice for inguinal hernia repair owing to its advantages and less complications, but it can’t be confirmed that local anaesthesia is better than spinal anaesthesia. It can be reliably concluded that local anaesthesia can be a preferred method in day-case hernia surgeries owing to its advantages of ease of administration and less complications.
THE ROLE OF MANAGERIAL ABILITY IN INDONESIA: INVESTMENT OPPORTUNITY SETS, ENVIRONMENTAL UNCERTAINTY, TAX AVOIDANCE
Authors: Dwi Laksono David Gilang , Firmansyah Amrie 
Published: November 2020

Purpose of the study: This study aims to obtain empirical evidence of the effect of investment factors that consist of investment opportunity sets and environmental uncertainty on tax avoidance and the role of managerial ability in moderating these effects.
Methodology: The analysis was conducted on 49 manufacturing companies listed on the Indonesia Stock Exchange from 2012 to 2018. It was chosen through a purposive sampling method, so 343 observations were obtained. This study engages two-panel data regression models, a model with and without moderation managerial ability. Also, this study employs factor analysis to produce investment opportunity sets that can represent this variable.
Main Findings: This study reveals that investment opportunity sets and environmental uncertainty positively affect tax avoidance. Meanwhile, managerial ability failed to moderate the effect of investment opportunity sets and environmental uncertainty on tax avoidance.
Implications: The results of the profiling can be used as an early warning, especially for account representatives and tax auditors at the Indonesia Tax Authority, so that potential tax exploration and examination can be more in-depth for firms that fulfill these characteristics. Also, this study provides advice to the Government of Indonesia to provide tax holidays for firms with high IOS who invest in the real sector and tax incentives for firms that are facing an environment with high uncertainty.
Novelty: This study deploys managerial ability as a moderating variable between the relationship of investment opportunity sets and environmental uncertainty to tax avoidance. The managerial ability has an important role in firms' IOS and environmental uncertainty faced by the firms because the level of managers will produce differences in the economic outcomes and the effectiveness of the discretion.
MOTIVATION FOR PURCHASING HALAL PRODUCTS: THE INFLUENCE OF RELIGIOSITY, TRUST, AND SATISFACTION
Authors: Nurrachmi Intan , Setiawan  , Saripudin Udin 
Published: November 2020

Purpose of the study: This study examines the influence of religiosity on the intention to purchase halal products through satisfaction and trust.
Methodology: The study was conducted through a survey method by distributing questionnaires to respondents using random sampling techniques. Respondents obtained totaled 295 from various backgrounds, gender, age, education, employment, and income. Data analysis was carried out through the SEM-PLS approach, and the tool used was WarpPLS.
Main Findings: The study results show that religiosity, trust, and satisfaction significantly influence the decision to purchase halal products.
Applications of this study: This paper will be useful for the manager of the halal product who prefers the factor that influences the usage dimension of human behaviour. The manager of halal product providers in the area of the halal industry will be able to improve the effectiveness of their implementation strategies on the halal industry. This finding can be made by increasing religious attributes that emphasize the importance of halal products as part of religious obligations. Besides, managers of the halal product must ensure that the products they sell meet the halal standards of official organizations. Products that meet halal standards must be guaranteed that they are labeled halal so that consumers are confident in the halal status of the products purchased even in the majority of Muslim countries.
Novelty/Originality of this study: This research links religiosity, trust, satisfaction, and interest in buying halal products. The study was limited to conducting in Indonesia, the country with the largest number of Muslims worldwide.
Dynamic Change of Pain Sensitisation at Acupoints in Patients with Knee Osteoarthritis and Disease Severity: A Multilevel Analysis of a Longitudinal Study
Authors: Geng Guoyan , Yu Yong , Sun Mingsheng , Yin Zihan , Chen Jiao , Zheng Hui , Cai Dingju , Luo Liaojun , Yang Chunxia , Zhao Ling , Liang Fanrong 
Published: December 2020

Abstract
Background and aim: Acupuncture alleviates pain and improves physical function in knee osteoarthritis (KOA). The therapeutic effect of acupuncture may depend on acupoint selection. This longitudinal study aimed to observe dynamic change of acupoint sensitization in knee osteoarthritis (KOA) patients, and to investigate the relationship between acupoint PPTs and disease severity. Methods: Two-hundred-and-forty-six KOA patients were enrolled in this longitudinal study from 5 clinical centers.; data from 216 samples were analyzed. All participants underwent PPT assessment of 19 acupoints once weekly for 4 weeks. Multilevel analysis of repeated measurement data was performed. Results: The PPTs at each acupoint decreased across the four timepoints, as the 19 acupoints became more pain-sensitive over time. Single-factor multilevel analysis showed a greater decrease in acupoint PPT at clinical stage ≥III than clinical stage I (p<0.05); PPTs at Xuehai (SP-10), Heding (EX-LE2), Ququan (LR-8), Yingu (KI-10), Xiguan (LR-7) and Qiuxu (GB-40) decreased more in imaging classification II than imaging classification I (p<0.05); PPT at Yaoyangguan (DU-3) decreased more in imaging classification ≥III than imaging classification I (p<0.05). Multi-factor multilevel analysis showed that the PPTs of Heding (EX-LE2), Liangqiu (ST-34), Ququan (LR-8), Dubi (ST-35), Weiyang (BL-39), Yinglingquan (SP-9), Xiguan (LR-7), Zusanli (ST-36), Yanglingquan (GB-34), Qiuxu (GB-40), and Weizhong (BL-40) decreased more with the progression of clinical stages (p<0.05); PPTs at Xuehai (SP-10), Heding (EX-LE2), Ququan (LR-8), Yingu (KI-10), Xiguan (LR-7), and Qiuxu (GB-40) decreased more in imaging classification II than imaging classification I (p<0.05); PPT at Qiuxu (GB-40) decreased more in imaging classification ≥III than imaging classification I (p<0.05).Conclusion: The correlated acupoints became more pain-sensitive over time, and the acupoint PPTs were in accordance with disease severity. Liangqiu (ST-34), Dubi (ST-35), Weiyang (BL-39), Yinglingquan (SP-9), Xiguan (LR-7), Zusanli (ST-36), Yanglingquan (GB-34), and Qiuxu (GB-40) were most related to disease severity, they should be recommended clinically.Trial registration: ChiCTR, ChiCTR1800014616. Registered 24 January 2018 - Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj=24037
Effect of Cisplatin Arterial Infusion (CAI) on Primary Nonmetastatic Pelvic Osteosarcoma: A Preliminary Study
Authors: Hu Xuantao , Chen Xia , Li Tao , Liu Zicheng , Guo Xiaoning , Ouyang Zhengxiao 
Published: December 2020

Abstract
Background: The critical role of arterial infusion chemotherapy in the multimodal treatment of extremity bone cancer has been investigated extensively, but few studies have focused on pelvic osteosarcoma. Therefore, we attempted to evaluate the clinical significance of arterial infusion chemotherapy in the treatment of pelvic osteosarcoma.Methods: We combined a cisplatin arterial infusion regimen with multidrug systematic chemotherapy as a neoadjuvant protocol for the treatment of pelvic osteosarcoma. The course number and dosage of cisplatin arterial infusion were adjusted to achieve a maximal tumor response evaluated by contrast-enhanced MRI per RECIST 1.1. Good responders received the same systematic combination for postoperative chemotherapy, and poor responders received second-line therapy. Twelve patients with nonmetastatic high-grade pelvic osteosarcoma were included. Survival, chemotherapy response and adverse events data were analyzed. Results: The mean follow-up period was 56.1 months. Four patients died of refractory tumor progression, and 1 patient with local recurrence had no evidence of disease for 27 months after receiving secondary amputation and resection. Kaplan-Meier survival analysis demonstrated a 57.8% overall survival and 52.5% event-free survival rate at 5 years. Eight of 12 patients had a >90% tumor necrosis rate according to histopathologic examinations. The rates of local adverse events were lower than those reported for extremity osteosarcoma. Conclusions: Our study initially indicated that the cisplatin arterial infusion regimen was a potential therapy with good tolerance in the treatment of pelvic osteosarcoma.
UJI RESISTENSI GENOTIPE TERPILIH DARI PLASMA NUTFAH IRRDB TERHADAP PENYAKIT GUGUR DAUN CORYNESPORA DENGAN METODE CAKRAM DAUN
Authors: Daslin Aidi , Fairuzah Zaida , Dalimunthe Cici Indriani 
Published: December 2020

Corynespora cassiicola (Berk & Curt) Wei adalah jamur penyebab penyakit gugur daun yang menginfeksi daun muda dan daun tua, dan dapat mengakibatkan daun karet gugur sepanjang tahun, sehingga menyebabkan tertundanya matang sadap, produksi lateks menurun pada tanaman menghasilkan, dan bahkan pada klon yang sangat rentan dapat mematikan tanaman. Seleksi terhadap berbagai genotipe karet sejak awal sangat penting untuk mengetahui tingkat ketahanannya terhadap penyakit. Pada penelitian ini dilakukan uji resistensi 29 genotipe terpilih dari plasma nutfah IRRDB terhadap penyakit gugur daun C. cassiicola, menggunakan Rancangan Acak Lengkap (RAL) faktorial dengan 60 perlakuan kombinasi dan 2 ulangan. Pengujian dilakukan terhadap isolat dari Sumatera Utara dan Aceh dengan klon PB 260 sebagai pembanding (kontrol). Semua genotipe diinokulasikan pada setiap isolat C. cassiicola dengan menggunakan metode cakram daun dan penilaian intensitas serangan penyakit diklasifikasikan dalam kategori resisten (0–20%), agak resisten (21–40%), moderat (41–60%), agak rentan (61–80%), dan rentan (81–100%). Hasil penelitian menunjukkan bahwa terdapat perbedaan resistensi genotipe plasma nutfah IRRDB terhadap isolat dan kontrol. PB 260 yang merupakan klon yang tergolong resisten terhadap kedua isolat. Genotipe PN 386, PN 398, PN 807, PN 5666, PN 5730, dan PN 5808 tergolong moderat terhadap isolat Sumatera Utara tetapi agak resisten terhadap isolat Aceh. Genotipe PN 803 tergolong agak rentan terhadap isolat Sumatera Utara dan moderat terhadap isolat Aceh sedangkan genotipe lainnya tergolong agak resisten terhadap kedua isolat. Isolat yang berasal dari Sumatera Utara mempunyai tingkat virulensi yang lebih tinggi dibandingkan dengan isolat yang berasal dari Aceh. How to Cite : Daslin, A., Fairuzah, Z., & Dalimunthe, C. I. (2011). Uji resistensi genotipe terpilih dari plasma nutfah IRRDB terhadap penyakit gugur daun Corynespora dengan metode cakram daun. Jurnal Penelitian Karet, 29(1), 16-24. Retrieved from http://ejournal.puslitkaret.co.id/index.php/jpk/article/view/106
Maurizio BETTINI, Homo sum. Essere “umani” nel mondo antico, Torino, Einaudi, 2019, 132 páginas, ISBN 978-88-0624088-2
Authors: Hernández Mayor María Dolores 
Published: November 2020

Reseña de
Maurizio Bettini, Homo sum. Essere “umani” nel mondo antico, Torino, Einaudi, 2019, 132 páginas, ISBN 978-88-0624088-2
Enrique Montero Cartelle, Speculum medicinae. Estudios de medicina latina antigua y medieval, Valladolid, Ediciones Universidad de Valladolid, 2018, 337 páginas, ISBN 978-84-8448-986-3
Authors: Paniagua Aguilar David 
Published: November 2020

Reseña de
Enrique Montero Cartelle, Speculum medicinae. Estudios de medicina latina antigua y medieval, Valladolid, Ediciones Universidad de Valladolid, 2018, 337 páginas, ISBN 978-84-8448-986-3
Pedagogical Compatibility as a Contemporary Problem
Authors: TOPUZYAN Aida 
Published: December 2020

One of the main problems of contemporary pedagogy is the necessity to consider pedagogical compatibility from an ideological point of view.
It dictates to study the problem of interaction between the teacher and the learner, affect one another's physical and psychological health, and maintaining one another's health in the pedagogical process. The article is based on the results of our questionnaire surveys, conversations among teachers, students, and their parents.
The surveys revealed that in some schools still persists the teacher’s authoritarianism and intolerance towards pupils. While organizing the pedagogical process, only a small part of teachers emphasized the health requirements of the lesson, most of them did not pay attention to the problem of pedagogical compatibility, in particular, the process of interaction between the student and teacher was not considered from the point of view of the health of both. However, the majority of teachers realize that the quality of their pupils' education, the effectiveness of their work, the motivation of children towards education, ensuring their creativity and safety at school largely depend on it.
Thus, the question was raised that in the processes of professional education and advanced training of teachers to seriously discuss this problem and provide relevant pieces of knowledge and competencies to the beneficiaries. All of this has prompted the need to enrich the theory of the term “Pedagogical compatibility” and develop a methodological system for its practical implementation. The article defines the essence of the new term “Pedagogical compatibility for health protection”. The principles, methods, the pedagogical conditions necessary for its implementation, the model of competencies the teacher needs in this field are presented.
A study of echo cardiographic abnormalities
Authors: Sravan kumar P  , Vinaya B  , Dinesh Babu J  , Akhila CR  
Published: November 2020

Prospective observational study conducted in Department of Respiratory Medicine, Chennai. 65 stable COPD (In patients and out patients) were recruited in this study which was appropriate by Institutional Human Ethical Committee. The selected patients were subjected to Spirometry, ECG, Echocardiography.Data was analysed by using appropriate statistical methods. Our study, included a total of 55 stable COPD patients between the age group of 40 to 70 years with the mean age of 55.01. There was a Male predominance of 63.6% with M: F ratio of 1.7:1. Based on the GOLD severity grading, 18.2%, 30.9%, 50.9% belongs to Mild, Moderate & Severe COPD respectively. 58.1% were smoker among which 14.5% had pack years of < 20 pack year and 43.6% had > 20 pack years of smoking. Majority of smokers with pack years of less than 20 had mild COPD. However majority of Smokers with >20 pack year majority belonged to severe (32.7%) group followed by 10.9% in moderate group. Among Non smoker (9.09%), 7.27% and 1.81% were in mild and moderate group respectively. The prevalence of Cardiac abnormality in the study group was analysed with ECG and Echocardiography. ECG abnormalities observed were as follows: P Pulmonale (43.6%), Right Axis Deviation (41.8%), Right Ventricular Hypertrophy (40%), Low voltage QRS complex (36.3%), Poor R wave progression (30.9%), T wave inversion (27.3 %) and Right Bundle Branch Block(20%).Echocardiographic changes observed were as follows: RA & RV dilatation (50.9%), Tricuspid regurgitation (47.3%), RWMA (10.9%) and LV dysfunction (7.3%). The normal pulmonary artery systolic pressure was observed in 21.8% patients. 16.3 %, 43.6% and 18.2 % were observed in Mild, Moderate and severe PAP respectively.
REGULACIÓN DE INSTALACIONES DE INFRAESTRUCTURA QUE GENEREN ELECTROMAGNETISMO EN AFECTACIÓN A LA LEGISLACIÓN PERUANA
Authors: Calderon Atoche Elias Israel 
Published: November 2020

Esta investigación tiene como objetivo dar a conocer como se afecta a la salud por consecuencias de la radiación electromagnética, la cual vulnera contamina y afecta el bienestar de la población peruana.Haciendo conocer que las radiaciones electromagnéticas son creadas a través un proceso enérgico de ondas que son generadas por electrones la cuales se propagan a través de toda la troposfera terrestre diferenciándoles en sus sus valores enérgicos creando estos espectros electromagnéticos de frecuencias muy fuertes y dañinos para la salud estos están son creados y se desarrollan a través del mal uso de instalaciones de infraestructuras de los medios tecnológicos de comunicaciones.Mediante diferentes estudios tecnológicos se ha Establecido que son dañinos y no existe un estudio adecuado de sus espacio en los cuales se ubicaran y se van a instalar, no teniendo ningún límite en las zonas y ni estudios organizados para hacer conocimiento exclusivamente de estas infraestructuras gigantescas.
Algunos estudios se han realizado en los organismos internacionales como el Consejo de Europa o la organización de la mundial de la salud establece la hipersensibilidad electrónica y que hay personas que son afectadas por estos campos electromagnéticos siendo estás invisibles al ojo humano y que llevan un peligro con efectos biológicos , desencadenando efectos en la salud y produciendo el gran cambio fisiológico detectable en el sistema biológico sobrepasando o presentando alguna dificultad en adaptación de su salud .
WATER AND WASTEWATER OPTIMIZATION IN MULTIPLE CONTAMINANTS NETWORK USING WATER PINCH TECHNOLOGY
Authors: Sasikala R. 
Published: November 2020

Data mining is the process of analyzing data from different perspectives and summarizing it into useful information. Data mining is applied to find patterns to help in the important tasks of medical diagnosis and treatment. In this paper, we present a sensor to measure water level in rivers, lakes, lagoons and streams. For such purpose and to prove our concept, we designed a pilot project through a micro-model that is constructed with a water level measurement sensor based on a simple open circuit that closes when in contact with water and experimentally tested into a water container under a controlled environment. The indicator for acidity, alkalinity, or basic is known as the PH value. A PH value of 7 means a substance is neutral. The lower value indicates acidity, and a higher value is a sign of alkalinity. Side effects that may occur after drugs are added to Bacteriostatic. Water includes fever, abscess formation, venous thrombosis or phlebitis, tissue death, and infections. We are going to implement weka tool to compare the time execution, frequency and an execution process by using a genetic algorithm. Here we used the Ultrasonic Sensor technique to measure the water level. Ultrasonic sensors are based on the measurement of the properties of acoustic waves with frequencies above the human audible range, often at roughly 40 kHz. They typically operate by generating a high-frequency pulse of sound, and then receiving and evaluating the properties of the echo pulse. In this study, the principle of water pinch technology, the optimization of water, steam allocation network have been studied and minimization of freshwater utility and wastewater generation in one of the petroleum refineries of Iran is taken into consideration. In order to research in this field and simplify the relevant calculations, an algorithm was developed and applied for reforming the network. Finally, the micro-model is tested by experimental tests under a controlled environment and satisfactory results are obtained. The experimental evaluation results showed a 99.2% of accuracy and which proves this mechanism effective and reliable in water optimization.