bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential anti-proliferative effects of chemical constituents and hemisynthetic derivatives from Scadoxus pseudocaulus (Amarillydaceae)
Authors: Laure Ngankeu Pagning Annie , Tamokou Jean-de-Dieu , Taj Muhammad Bushra , Ngnokam David , AzefackTapondjou Leon , Shaiq Ali Mohammad , Waqar Hameed Muhammad 
Published: October 2020

Background: Biological significance of Amaryllidaceae is well advocated from the literature. In Cameroon, plants from this fam- ily are routinely used for the cure of liver, cancer and cardiovascular diseases. To date, no scientific investigation corresponding to the anti-cancer activity of extracts and isolated compounds of Scadoxus pseudocaulus is available.
Objective: Current study is focused to elaborate the anti-proliferative effects of natural isolates (compounds 1-6, 9) and hemi-synthetic analogs (compounds 7-8) extracted from S. pseudocaulu.
Methods: Column chromatography of the ethyl acetate extract followed by purification of different fractions led to the isolation of seven compounds (1 – 6, 9). Esterification reaction of compound 6 was carried out using butyroyl chlorides and triethylamin to produce two derivatives (7 – 8). The cytotoxic activity was performed after staining of treated cells with florescent dye propid- ium iodide. Dead cells were detected using cytometer FL2 or FL3 channels/filters.
Results: Trans-derivative of narciclasine (a natural isolate from S. pseudocaulus), was found to be most potent among all tested compounds. Its effects were more significant on low malignant follicular lymphoma (DoHH2 cells) as compared to highly ma- lignant (EBV infected) Burkitts lymphoma (Raji cells).
Conclusion: From our results, narciclasine appears to hold the potential of a lead molecule that can be used to bridge the ther- apeutic gaps in cancer research.
Keywords: Scadoxus pseudocaulus; Amaryllidaceae; 7-deoxy-trans-dihydronarciclasin; farrerol; derivatization; cytotoxic activity.
Parent-reported feeding and swallowing difficulties of children with Autism Spectrum Disorders (aged 3 to 5 years) compared to typically developing peers: a South African study
Authors: Viviers Mari , Jongh Marguerite , Dickonson Lindsay , Malan Roxanne , Pike Tamaryn 
Published: October 2020

Background: Research on aspects of neurodevelopment such as feeding and swallowing difficulties in children with Autism Spectrum Disorders (ASD) is limited in low and middle income countries such as South Africa.
Method: A descriptive comparative group design was used to investigate feeding and swallowing difficulties of young children with ASD in comparison to typically developing peers. The Brief Autism Mealtime Behavioural Inventory (BAMBI) was used.
Results: Findings indicated a significant difference in the severity of feeding and swallowing difficulties between the two groups. Difficulties such as food selectivity, sensory processing difficulties, oral-motor difficulties and symptoms of dysphagia were iden- tified. The findings added to the existing global literature on feeding and swallowing difficulties in young children with ASD but provide a unique first perspective on these difficulties in South African children with ASD.
Conclusion: Findings also highlighted the use of the BAMBI as an adjunct clinical tool to encourage comprehensive parental report during feeding assessment in this population. Cultural adaptation of the BAMBI for future use in African countries should be considered. A better local understanding of the parental perspective on the multidimensional nature of the feeding and swallowing difficulties displayed by young children with ASD was obtained.
Keywords: Parent-reported feeding; swallowing difficulties; Autism Spectrum Disorders; South Africa.
Prevalence of Candida spp. and age-related disparities amongst women presenting with vaginitis at the Obstetrics and Gynaecology (O&G) Clinic in a Tertiary hospital in Port Harcourt, Nigeria
Authors: Mbakwem-Aniebo Chiaka , Uche Osadebe Anwuli , Athanasonny Eunice , Omezurike Okonko Iheanyi 
Published: October 2020

Background: Vaginitis, an infection of the lower genital tract in women, is known to be triggered by the overgrowth of the vagina’s naturally occurring microorganisms.
Objective: This study looked at the prevalence of Candida spp. and age-related disparities amongst women presenting with vag- initis at the Obstetrics and Gynaecology (O&G) clinic in a tertiary hospital in Port Harcourt, Nigeria.
Methods: One hundred high vaginal swabs were collected from pregnant and non-pregnant women and examined microscop- ically and microbiologically.
Results: Age-group 20–29 years had the highest incidence of candidal vaginitis. There was a higher occurrence of yeast cells in pregnant than in non-pregnant participants while the non-pregnant women had a greater level of bacterial cells. Forty (40) of the samples contained yeasts of Candida species representing a 40% prevalence. Three species of Candida were identified with C. albicans dominating. Of the 40 samples positive for Candida spp., 30 (75.0%) were confirmed to be C. albicans. The remaining isolates were C. tropicalis (15.0%) and C. parapsilosis (10.0%).
Conclusion: The findings in this study would play a role in the future management of Candida-induced vaginitis.
Keywords: Candida; epidemiology; prevalence; vaginitis; vulvovaginal candidiasis.
ATENCION PLENA Y LIDERAZGO: PUNTOS DE CONVERGENCIA EN LA EXHIBICIÓN DE NIVELES DE LIDERAZGO
Authors: Pimentel Bernal Paul 
Published: October 2020

Este artículo académico es una revisión de la literatura de sobre las relaciones existentes entre atención plena o mindfulness y su relación con los niveles de liderazgo con el objetivo de obtener una aproximación clara si la relación entre ambos ha sido relevante para la comunidad científica. La presente investigación se ocupa de definir y clarificar lo que se entiende por Conciencia Plena o Atención Plena, sus componentes o elementos, la naturaleza de su origen, las herramientas de cómo se mide y si existen puntos de convergencia entre el liderazgo y su medición. De la investigación se concluye que este es un cuerpo de investigación que está en construcción rápidamente por lo que se debe seguir avanzando en la evaluación sobre una relación directa o causal entre los niveles de liderazgo y los niveles de Conciencia plena o Atención Plena.
Effect of Home Base Glucose Monitoring & Self Dose Adjustment of Insulin on Glycosylated Hemoglobin
Authors: Maulik Shah  , Triya Malde  , Falgun Gondalia  , Sonal Shah  
Published: October 2020

Background: Type1 Diabetes Mellitus (T1DM) is the most common endocrine metabolic disorder of childhood casing significant mortality and morbidity in childhood. Home Monitoring of Blood Glucose (HMBG) and Supplements of insulin as required depending on the blood glucose level at that time is a very important aspect of management in T1DM. The Goal of this study was to determine whether frequent checking of home base blood glucose (HMBG) levels accompanied with insulin self dose adjustment, will lead to improved metabolic control as assessed by reduction in the Glycosylated hemoglobin values (HbA1c).Subject and Method:This study was conducted in G.G.Hospital,,M.P.Shah Medical college,Jamanagar between October 2012 to September 2013 for a period of 1 year including OPD and ward patients. Retrospective analysis of clinical profile of 37patients with T1DM attending our OPD between the age group of 2 to 16 years.A detailed clinical and family history, educational level of parents and insulin regime and insulin dose was recorded. Result:Age distribution in our study showed that 62% cases in the age of more than 10 years, 32% cases in the age group 5-10years and 2 % cases falling in the age group 0-2 years, with male to female ratio of a 1:1.7. The most frequently seen symptoms were polyuria (53%), breathlessness (48%),polydipsia (46%), vomiting (29%) of cases and 82%of the patients were ketotic at the time of presentation. In family members most common associated co-morbidity is type 2 DM(21% ) , hypertension(21%) & thyroid dysfunction (19%). split regimen was observed in (70%)and basal bolus regime in (30%). split mix regime 11(42%) had good(<7GHb) wheaeas Basal bolus regime 6(54%) of them had good control p=0.0308(<0.05). Conclusion:Regular Home monitoring of Blood glucose(HMBG) along with education on diabetes self management and regular contact with a member of a medical team for insulin dose adjustments with advice on meal planning and physical activity improve the metabolic control (as assessed by HbA1c levels) in children with T1DM.
MEMAHAMI KISAH PENCIPTAAN MANUSIA DAN ALAM SEMESTA: Sebuah Pendekatan Literer Terhadap Kejadian 1-2
Authors: Heri Lim  
Published: October 2020

Abstrak: Teks Alkitab dibuka dengan sebuah narasi tentang penciptaan, sebuah teks yang menggambarkan keagungan Allah, sekaligus juga menjadi sebuah topik diskusi di dalam dan di luar kekristenan. Dalam pandangan kekristenan, berbagai penafsiran berbeda disodorkan untuk menjelaskan narasi penciptaan manusia dan kosmos. Artikel ini mencoba untuk menawarkan sebuah sudut pandang yang diharapkan dapat berdialog dengan penafsiran yang lain, tetapi tetap tidak meninggalkan kesetiaan Injili. Artikel ini bukan merupakan eksegesis ayat per ayat kitab Kejadian 1-2, tetapi lebih merupakan sebuah cara untuk memahami narasi penciptaan dalam Kejadian 1-2 secara utuh. Dalam hal ini penulis mencoba untuk mengajukan sebuah pendekatan literer dalam membaca dan memahami narasi penciptaan dalam Kejadian 1-2.

Abstract: The biblical text is opened with a narrative about creation. a text that illustrates the majesty of God, as well as becomes topic of discussion within and outside Christianity. In the Christian poin of view, many interpretations are offered to explain the narrative of the human and the cosmos creation. This article tries to offer a perspective that is expected to make a dialogue with other interpretations, but still does not leave evangelical commitment. This article is not a verse by verse exegesis of Genesis 1-2, but rather a way to understand the creation narrative in Genesis 1-2 as a whole. In this case the writer tries to propose a literary approach in reading and understanding the narrative of creation narrative in Genesis 1-2.
KEKRISTENAN DAN NASIONALISME DI INDONESIA
Authors: Aritonang Arthur 
Published: October 2020

“Kekristenan dan Nasionalisme di Indonesia” membahas mengenai sejarah kekristenan di Indonesia yang diasumsikan sebagai agama yang pro terhadap penjajah dari Barat namun asumsi itu tidak benar sebagai bukti ada banyak tokoh Kristen yang ikut memperjuangkan kemerdekaan Indonesia dengan didasarkan semangat nasionalisme. Kemudian pasca-kolonial Belanda kekristenan ingin menampilkan wajah baru yang sungguh-sungguh keindonesiaan dengan lahirnya organisasi DGI/PGI. Namun seiring waktu ketika berakhirnya era orde baru dan memasuki era reformasi, kekristenan dan masyarakat lainnya di Indonesia menghadapi arus gelombang yang mengatas-namakan agama yang pergerakannya cukup masif dibandingkan di era orde lama diantaranya: kelompok Islam fundamentalis yang ingin menjadikan NKRI bersyariat Islam, adanya gerakan politik transnasional HTI yang ingin menghidupkan kembali kejayaan Islam pada abad ke-6 dan faham Wahabisme yang sarat dengan kekerasan. Persoalan lainnya ialah adanya kemiskinan yang terstruktur akibat dari krisis moneter yang melanda di Indonesia tahun 1997. Melalui masalah ini, setiap agama-agama di Indonesia harus melakukan konvergensi atas dasar keprihatinan yang sama.
Abstract: Christianity and Nationalism in Indonesia” discuss the history of Christianity in Indonesia, which is assumed to be a religion that is pro to Western colonialism. Still, this assumption is incorrect as evidence that many Christian figures fought for Indonesian independence based on the spirit of nationalism. Then post-colonial of Dutch, Christianity wanted to be presented a truly Indonesian face with the birth of the DGI / PGI organization. But over time when the end of the new order and entering the era of reform, Christianity and the other societies in Indonesia faced challenges in the name of religion whose movements were quite massive compared to the old order including fundamentalist Islamic groups who wanted to make the Republic of Syariat Muslim Indonesia, a transnational HTI political movement that wanted to revive the glory of Islam in the 6th century and the ideology of Wahhabism which is loaded with violence. Another problem is the existence of structured poverty due to the monetary crisis that hit Indonesia in 1997. Through this problem, every religion in Indonesia must converge on the basis of the same concerns.
MODEL ORTODOKSI-ORTOPRAKSI-ORTOPATI: Usulan Model Berteologi sebagai Cara Hidup Kaum Injili di Dunia Pascakebenaran
Authors: Yohanes Hendra 
Published: October 2020

Era pascakebenaran (post-truth) ditandai dengan pudarnya relevansi kebenaran dan verifikasi fakta digantikan dengan preferensi pribadi dan tarikan emosional. Dalam konteks pemilihan umum Indonesia pada tahun 2014 dan 2019, berbagai hoaks bernuansa SARA yang bermunculan mengancam kohesi sosial di bangsa ini. Dengan demikian, pascakebenaran tidak lagi sekadar menjadi isu di kalangan akademisi, tetapi juga dipertunjukkan secara masif di ruang publik. Bagaimana kaum injili menanggapi problematika pascakebenaran yang kompleks ini? Artikel ini mengusulkan sebuah model teologi yang integratif dalam menghadapi tantangan-tantangan di dunia pascakebenaran, yakni model Ortodoksi-Ortopraksi-Ortopati sebagai cara hidup kaum injili. Di akhir artikel ini, model berteologi ini diimplementasikan untuk menanggapi problematika post-truth yang berkembang dewasa ini di Indonesia.
Abstract: The post-truth era is indicated by the eclipsing of the relevance of truth and fact verification replaced by personal preference and emotional appeal. In the context of Indonesia's national elections in 2014 and 2019, multitude of hoaxes emerged with respect to tribal affiliations, religion, race and societal groups and threatened social cohesion in this nation. Correspondingly, post-truth not merely an issue in the academia but also is massively demonstrated in the public sphere. How do the evangelicals respond to the complex problem of post-truth? This article proposes an integrative theological model in facing challenges in a post-truth world, namely the Orthodoxy-Orthopraxis-Ortopathy Model as the evangelicals' way of life. At the end of this article, this theological model implemented to respond post-truth problems that recently emerged in Indonesia.
PENGARUH DOMINAN CASH RATIO DAN DEBT TO ASSET RATIO TERHADAP RETURN ON EQUITY DAN RETURN ON ASSETS PADA PERUSAHAAN ASTRA OTOPARTS DI BURSA EFEK INDONESIA
Authors: Nasyaroeka Jhon 
Published: October 2020

This research is to find out which influence is the most dominant between cash ratio and debt to assets ratio to return on equity and return on assets on astra otoparts companies listed on the Indonesia Stock Exchange. This research also provides information on the dominant influence of cash ratio on return on equity and Return on Assets and the dominant influence of debt to assets ratio to return on equity and return on assets. The results obtained from this study are the dominant influence of cash ratio and debt to assets ratio to return on assets. This shows the amount of contribution of company assets.
Keywords:
Dominant influence, Cash ratio, Debt to asset ratio, Return on equity, Return on assets.

A B S T R A K:
Penelitian ini adalah untuk mengetahui pengaruh mana yang paling dominan antara rasio kas dan rasio hutang terhadap aset terhadap return on equity dan return on asset pada perusahaan astra otoparts yang terdaftar di Bursa Efek Indonesia. Penelitian ini juga memberikan informasi tentang pengaruh dominan rasio kas terhadap pengembalian ekuitas dan Imbal Hasil Aset dan pengaruh dominan rasio utang terhadap aset terhadap pengembalian ekuitas dan laba atas aset. Hasil yang diperoleh dari penelitian ini adalah pengaruh dominan rasio kas dan rasio hutang terhadap aktiva terhadap pengembalian aktiva. Ini menunjukkan besarnya kontribusi aset perusahaan.
Kata kunci:
Pengaruh dominan, Rasio kas, Rasio utang terhadap aset, Laba atas ekuitas, Laba atas aset
Estimating a New Keynesian Wage Phillips Curve for South Africa
Authors: Dadam Vincent , Viegi Nicola 
Published: October 2020

Abstract
This article estimates a New Keynesian Wage Phillips Curve for South Africa to investigate the responsiveness of nominal wages to labor market conditions. The estimation is based on a model with staggered nominal wages setting, where all variations in hired labor input are taking place at the extensive margin. First, we estimate the model using aggregate data from 1971 to 2013. Aggregate estimation results show that private sector nominal wages are not very responsive to employment conditions, while they also reveal a certain sensitivity to inflation and quite a good correlation with inflation expectations. On the other hand, the relationship between nominal wage inflation and price inflation is quite strong and robust for the whole sample. However, it becomes quantitatively weak for the inflation targeting period. In that period, trade unions’ inflation expectations are, instead, strongly correlated with nominal wage inflation. In the second part of the article, we assess the response of nominal wages to employment, labor productivity, and output prices, given the reservation wage using a panel of nine industrial sectors over the period 1970–2013. The findings confirm that nominal wage inflation has consistently outpaced the growth in productivity, even after correcting for price inflation, and that employment conditions had little effect on wage dynamics. We also test for the possibility that the dynamic of wages is anchored by an underlined reservation wage to investigate the presence of an error correction term in the wage equation for South Africa. The overall picture that emerges from the analysis is that of a wage formation mechanism that is very insensitive to overall macroeconomic conditions.
Growth and Inequality: The South African Case in International Context—The Central Role of the Labor Market
Authors: Fedderke Johannes W. 
Published: October 2020

Abstract
The relationship between economic growth and inequality has not been settled. Using South African time series data, the core finding of this article is that growth and inequality codetermine one another: growth lowers inequality, and falling inequality in turn serves to stimulate growth. There are additional statistically and substantively significant drivers of inequality in South Africa. Labor absorption (job creation) is the most important of these. The opening of the South African economy post 1990, the lowering of credit rationing in the economy in the 1990s, and the fiscus all prove to exert important influence on the net inequality outcome also. The findings imply that the strongest policy levers suitable for raising average welfare and lowering inequality are policies designed to stimulate growth, increase labor absorption, extend credit to entrepreneurs, ensure household credit is broad-based, and ameliorate the disruptive impacts of globalization on labor markets.
The Promotion of Equality and Prevention of Unfair Discrimination Act 4 of 2000: Proposals for Legislative Reform to Promote Equality through Schools and the Education System
Authors: Kok Anton , Xaso Lwando , Steenekamp Annalize , Oelofse Michelle 
Published: October 2020

The Promotion of Equality and Prevention of Unfair Discrimination Act 4 of 2000: Proposals for legislative reform to promote equality through schools and the education system
In this article, we focus on how the education system can be used to promote equality in the context of changing people’s hearts and minds – values, morals and mindsets. The duties contained in the Promotion of Equality and Prevention of Unfair Discrimination Act 4 of 2000 (‘Equality Act’) bind private and public schools, educators, learners, governing bodies and the state. The Equality Act calls on the state and all persons to promote substantive equality, but the relevant sections in the Equality Act have not been given effect yet, and are therefore currently not enforceable. We set out how the duty to promote equality should be concretised in the Equality Act to inter alia use the education system to promote equality in schools; in other words, how should an enforceable duty to promote equality in schools be fashioned in terms of the Equality Act. Should the relevant sections relating to the promotion of equality come into effect in their current form, enforcement of the promotion of equality will take the form of obliging schools to draft action plans and submit these to the South African Human Rights Commission. We deem this approach inadequate and therefore propose certain amendments to the Equality Act to allow for a more sensible monitoring of schools’ duty to promote equality. We explain how the duty to promote equality should then play out practically in the classroom to facilitate a change in learners’ hearts and minds.
FAMÍLIAS DE CLASSES POPULARES, DESIGUALDADE SOCIAL E LITÍGIOS QUE ENVOLVEM CRIANÇAS: GARANTIA OU VIOLAÇÃO DE DIREITOS?
Authors: Pinheiro Jordana de Carvalho , Sousa Sonia Margarida Gomes 
Published: October 2020

Este artigo se propõe a apresentar os significados atribuídos pelos entrevistados, profissionais do Direito atuantes no Direito das Famílias e da Criança, acerca do papel desempenhado pela família nos litígios que envolvem crianças. Os profissionais entrevistados frequentemente apontaram o “fracasso” da família como motivador da intervenção judicial na vida das crianças, do excesso de exposição, da tensão provocada e da potencial formação de trauma nas crianças atendidas pelo Judiciário. Nessas entrevistas, busca-se identificar as contradições que cercam esse papel, que ora se mostra como garantia de direitos e ora como violador. Tais contradições expressam a severa distância que ainda separa a criança da concretização efetiva de políticas públicas que garantam plenamente seus direitos, sobretudo no que tange as crianças oriundas das classes populares atingidas pela desigualdade social. A análise e o alicerce teórico deste texto se norteiam pela Psicologia Sócio-Histórica de Vigotski, uma perspectiva crítica que admite a contradição e aspira a uma transformação das relações sociais.
Palavras-chave: psicologia sócio-histórica; direitos da criança; dialética exclusão/inclusão social; sistema de garantias de direitos; famílias de classes populares.