bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuroimmun-moduláció az emésztőcsatorna nyálkahártyájában
Authors: Fehér Erzsébet , Altdorfer Károly 
Published: September 2020

Absztrakt:
Az enteralis idegrendszerben termelt neuropeptidek szerepet játszanak az
immunsejtek működésében, részt vesznek a gyulladás fokozásában és annak
csökkentésében. Összefoglaló munkánkban azt elemeztük, hogy a gyulladás milyen
hatást fejt ki az idegelemek és immunsejtek neuropeptid-tartalmára. Gyulladásos
mintákat (human gastritis, állatkísérletes indukált colitis, sztreptozotocinnal
indukált diabetes mellitus) és kontrollpreparátumokat hasonlítottunk össze. A
neuropeptid-tartalmú idegrostok és immunsejtek mennyiségét vizsgáltuk
(immunhisztokémia, konfokális lézermikroszkópia, elektronmikroszkópia),
esetleges közeli kapcsolatokat kerestünk. Gyulladásos folyamatokban (gastritis,
kísérletes colitis, diabetes mellitus) a substance P, neuropeptid Y és vasoactiv
intestinalis peptid pozitív idegrostok mennyisége szignifikánsan megemelkedett,
s ezzel párhuzamosan a nyálkahártyában lévő immunkompetens sejtek (lymphocyták,
plazmasejtek, hízósejtek) száma szintén jelentős mértékben megnőtt (p<0,001).
Gyulladás hatására az immunsejtek aktiválódtak és pozitívan jelölődtek substance
P, neuropeptid Y és vasoactiv intestinalis peptid elleni antitestekkel.
Kontrollanyagban sohasem sikerült nagyon közeli idegrost-immunsejt közötti
morfológiai kapcsolatot kimutatni, viszont gyulladás hatására számos immunsejt
mellett található idegrostköteg, ahol az idegrostok egy része immunpozitivitást
mutat substance P-re, neuropeptid Y-ra és vasoactiv intestinalis peptidre.
Konfokális lézermikroszkóppal kettős jelöléssel bizonyítottuk, hogy
tumornekrózisfaktor-alfa- és nukleárisfaktor-kappa-B-pozitív immunsejtek egy
részében a substance P kolokalizációban fordul elő. A tumornekrózisfaktor-alfa
és nukleárisfaktor-kappa-B-pozitív immunsejtek mennyiségének emelkedése
korrelált (párhuzamosan emelkedett) a substance P-immunreaktív idegrostok
mennyiségének növekedésével human gastritisben. Eredményeink alátámasztják, hogy
substance P-antagonisták vagy neuropeptid Y és vasoactiv intestinalis peptid
alkalmazása az utóbbi évtizedben új terápiás lehetőség lehet a krónikus
gyulladások kezelésére. Orv Hetil. 2020; 161(35): 1436–1440.
How Old is the Hebrew Bible? A Linguistic, Textual, and Historical Study, por Ronald Hendel y Jan Joosten. New Haven, CT: Yale University Press, 2018. Pp. xvi + 221.
Authors: Richter Eric E. 
Published: September 2020

Ronald Hender y Jan Joosten han publicado esta obra que defiende vigorosamente la posibilidad de fechar la composición de los libros del AT a partir de las diferencias lingüísticas diacrónicas del idioma hebreo.
Adaptación de la Escala de Valoración de la Conducta Violenta y Riesgo de Reincidencia (EVCV-RR) en una muestra penitenciaria peruana
Authors: Conde Mendoza Jari Yasser 
Published: September 2020

Los sistemas judiciales exigen a los psicólogos evaluar a sujetos que cumplen condenas en establecimientos penitenciarios con el fin de valorar la posibilidad que estos puedan reinsertarse anticipadamente a la sociedad. Para ello, los psicólogos penitenciarios han desarrollado técnicas y procedimientos de evaluación del riesgo de la conducta violenta basadas en la identificación de factores de riesgo. El objetivo de este estudio fue adaptar el primer instrumento de evaluación del riesgo de violencia al contexto penitenciario peruano. Se estableció la validez de contenido por juicio de expertos, con una muestra de 303 internos. La validez de constructo fue establecida a través del análisis factorial exploratorio y confirmatorio. Por último, se estableció la precisión diagnóstica, por medio de la curva ROC. Los resultados indican que la adaptación de la EVCV-RR es un instrumento adecuado para valorar el riesgo de criminógeno.
Estudio de las Características Psicométricas de la forma corta del Test de Beery con el modelo Rasach
Authors: Escurra Mayaute Luis Miguel , Delgado Vásquez Ana Esther , Aparcana Carrasco Andrés 
Published: September 2020

Se realizó el estudio de las principales características de la forma corta del Test de Desarrollo Visomotor de Beery, desarrollada por Salazar y Delgado en 1985, bajo los supuestos del modelo de Rasch.Se aplicó la prueba a 1210 sujetos de Lima Metropolitana, (49.9% mujeres y 50.1% hombres) pertenecientes a centros educativos estatales y noestatales, de 1°, 2° y 3° grado de primaria y que residen en zonas urbanas y urbanas-marginales.Los resultados confirman que la prueba conformada por 12 ítems, al ser analizados bajo el modelo probabilístico de Rasch obtienen valores que no se adecuan al modelo, en tanto que al eliminar 6 ítems se conforma una escala que cumple con todos los supuestos del modelo. Se computaron los valores de los ítems-parámetros y los persona-parámetros, así como los análisis estadísticos básicos para evaluar la bondad de ajuste al modelo.
La participación indígena en la actividad turística en territorio Brörán-Térraba, Costa Rica, 2018
Authors: Murillo Masís Rodrigo , Ruiz Umaña Yuliana 
Published: September 2020

En el territorio indígena Térraba, ubicado en la provincia de Puntarenas en Costa Rica, su pueblo participa en el desarrollo del turismo a través de prácticas que no tengan un mayor impacto en la naturaleza y que no implique una pérdida de su cultura. Diversos estudios indican que la población indígena costarricense sufre altos niveles de desigualdad, y además, cuentan con menores tasas de participación en la economía. El trabajo analiza mediante un método cualitativo y de carácter etnográfico, por medio de las técnicas de entrevistas a profundidad y observación participante cómo las iniciativas de turismo, pueden ser ejemplo en la organización de actividades económicas y el empoderamiento para el desarrollo de comunidades indígenas. La principal conclusión de este trabajo indica que para la gestión del turismo sostenible ha sido fundamental una participación crítica por parte de los indígenas de la asociación Mano de Tigre, el Descanso y el Rincón Ecológico dentro de la comunidad Bröran. Se recomienda optimizar los servicios y ofertar el destino ya que cuenta con un alto potencial turismo nacional e internacional.
Palabras clave: empoderamiento; turismo y sociedad; desigualdad.
Evaluation of protein sparing effect in Nile tilapia Oreochromis niloticus fed with organic selenium supplemented diet
Authors: Pattipeilohy Christian Ernsz , Suprayudi Muhammad Agus , Setiawati Mia , Ekasari Julie 
Published: September 2020

ABSTRACT

The objective of this research was to determine the optimum level of organic selenium supplementation in improving the growth performance of Nile tilapia Oreochromis niloticus fed with diet containing low protein level. Basal diet was formulated to contain 28% protein with three different levels of organic selenium supplementation, namely 0 (control), 3, and 6 mg Se/kg feed. Furthermore, to evaluate selenium function on protein utilization and sparring effect, a diet with 30% of protein content was also used as a comparison. In this regard, this study was conducted using a completely randomized experimental design with four treatments and three replications. Nile tilapia with an average body weight of 8.05 ± 0.25 g were reared in the 100×50×50 cm3 aquarium at a density of 15 fish/aquarium. The experimental fish were reared for 60 days and fed three times daily to apparent satiation levels. Dietary supplementation of organic Se resulted in higher fish biomass, lower feed conversion ratio, higher protein retention and daily growth rate compared to the control diets with 28% and 30% protein levels. In conclusion, dietary supplementation of organic Se at 3 mg organic Se/kg feed could significantly increase protein utilization and improve the growth performance of Nile tilapia.

Keywords: tilapia, protein sparing effect, organic selenium, feed

ABSTRAK

Tujuan dari penelitian ini adalah menentukan tingkat suplementasi selenium organic pada pakan untuk meningkatkan kinerja pertumbuhan ikan nila Oreochromis niloticus. Pakan basal diformulasikan mengandung 28% protein dengan tiga tingkat selenium organik yaitu 0 (kontrol), 3, dan 6 mg Se/kg pakan. Selanjutnya untuk mengevaluasi penggunaan selenium pada pemanfaatan protein dan efek sparring, pakan dengan 30% protein juga ditambahkan sebagai perlakuan pembanding. Penelitian ini menggunakan rancangan acak lengkap dengan empat perlakuan dan tiga ulangan. Ikan nila dengan bobot rata-rata adalah 8.05 ± 0.25 g dipelihara dalam akuarium 100 × 50 × 50 cm3 dengan kepadatan 15 ikan/akuarium. Ikan dipelihara selama 60 hari dan diberi pakan tiga kali sehari secara at satiation. Pemberian pakan dengan suplementasi Se organic menghasilkan biomassa ikan yang lebih tinggi, rasio konversi pakan yang lebih rendah, retensi protein dan laju pertumbuhan harian yang lebih tinggi daripada perlakuan control dengan kadar protein 28% dan 30%. Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa suplemtasi pakan ikan nila dengan 3 mg Se organik/kg pakan dapat meningkatkan pemanfaatan protein pakan dan kinerja pertumbuhan ikan Nila.

Kata kunci: ikan nila, protein sparing effect, selenium organik, pakan.
The future of internationalization of higher education in challenging global contexts
Authors: De Wit Hans 
Published: September 2020

Internationalization has been over the past three decades one of the key focus points of (inter)national and institutional policies for higher education, with two related components: internationalization abroad, and internationalization at home. The 'abroad' component: mobility of students, faculty and programs, has been more predominant than the 'at home' component: internationalization of the curriculum and learning outcomes, perceived as a neoliberal and western paradigm. What will be the future of internationalization? Do we see a return from competition to cooperation? What will be the impact of the changing global economic, ecological and political context? These questions will be addressed in a critical analytical way in this paper, taking into account the impact of Covid-19 on the internationalization of higher education.
Management of Herbicide and Fertility Levels on Weeds and Kentucky Bluegrass Turf1
Authors: Johnson B. J. , Bowyer T. H. 
Published: September 2020

AbstractTo maintain a good quality weed‐free turf, it is usually necessary to apply herbicides for weed control and fertilizer for turfgrass growth. It may be possible to substitute a specific amount of fertilizer for herbicides in maintaining a good quality turf. A field experiment was conducted in Kentucky bluegrass (Poa pratensis L. ‘Common’) turf on Congaree loam (Fluventic Dystrochrepts) at Blairsville, Ga. to determine minimum herbicide and fertilizer combination treatments needed for effective weed control and turfgrass quality.Nitrogen (N) and preemergence herbicides applied to the same plots for 4 consecutive years controlled a higher percentage of large crabgrass [Digitaria sanguinalis (L.) Scop.] than when either was applied alone. However, MSMA (monosodium methanearsonate) controlled large crabgrass effectively whether the chemical was applied to plots treated with N or to plots receiving no fertilizer. Dandelions (Taraxacum officinale Weber) were effectively controlled with MSMA. When MSMA was not used, dandelion control was generally greater in plots treated with 6 kg N/are than when treated with 3 kg N/are. In 1 of 4 years, Kentucky bluegrass was severely injured by combination treatments of MSMA with either isobutylidene diurea (IBDU), ureaformaldehyde (UF), or sulfur‐coated urea (SCU). The injury was not as severe when MSMA was applied alone or with ammonium nitrate (AN). There was less red thread disease [Corticuim fuciforme (Berk.) Wakef.] in plots treated with MSMA than in those treated with preemergence herbicides. After 4 years, there was generally less disease in AN treated plots than in the slow release N treated plots. However, the turf had less red thread disease in plots where 6 kg/are of slow release N was applied than in plots where only 3 kg N/are was applied.
Reuse of municipal wastewater for different purposes based on a modular treatment concept
Authors: Nahrstedt Andreas , Gaba Anil , Zimmermann Barbara , Jentzsch Timo , Kroemer Kerstin , Tiemann Yannick , Harsanyi Lajos , Buchta Patrick , Doelchow Uli , Lipnizki Jens , Mende Katharina , Koch Thomas , Rohn Anja 
Published: September 2020

Abstract
Due to water scarcity and water pollution, the importance of water reuse is increasing more and more. As part of a German research programme on water reuse, the effluent of a wastewater treatment plant in the coastal region of northern Germany was used to investigate within the project MULTI-ReUse the direct treatment of tertiary effluent for usage in different applications in industry or agriculture. A modular constructed pilot system has been operated to optimize different treatment chains producing different water qualities simultaneously. The technological focus was put on membrane technologies, namely ultrafiltration (UF) and reverse osmosis (RO), and also biofiltration, adsorption and disinfection were part of the piloting. Beside the development of monitoring strategies for ensuring biological and chemical safe water qualities, the operational stability and the safe transport of water to the consumers were examined. The direct treatment of wastewater is a demanding task due to the lack of dilution and hydraulic retention time in the receiving water (environmental buffer). However, the multiple barrier approach guaranteed constant secure water. Fine adjustments of individual processes were particularly important. A stable operation of the UF could be realized in particular by using more or less intermittent inline coagulation as coating. The RO performance could be improved significantly by using monochloramine as disinfectant to minimize biofouling.
Novel Protein Sequence Comparison Method Based on Transition Probability Graph and Information Entropy
Authors: Qi Zhaohui , Wen Xinlong 
Published: September 2020

Aim and Objective:Sequence analysis is one of the foundations in bioinformatics. It is widely used to find out the feature metric hidden in the sequence. Otherwise, the graphical representation of biologic sequence is an important tool for sequencing analysis. This study is undertaken to find out a new graphical representation of biosequences.Materials and Methods:The transition probability is used to describe amino acid combinations of protein sequences. The combinations are composed of amino acids directly adjacent to each other or separated by multiple amino acids. The transition probability graph is built up by the transition probabilities of amino acid combinations. Next, a map is defined as a representation from transition probability graph to transition probability vector by k-order transition probability graph. Transition entropy vectors are developed by the transition probability vector and information entropy. Finally, the proposed method is applied to two separate applications, 499 HA genes of H1N1, and 95 coronaviruses.Results:By constructing a phylogenetic tree, we find that the results of each application are consistent with other studies.Conclusion:The graphical representation proposed in this article is a practical and correct method.
Assessment of White Matter Lesions in Parkinson's Disease: Voxel-based Analysis and Tract-based Spatial Statistics Analysis of Parkinson's Disease with Mild Cognitive Impairment
Authors: Pu Wei , Shen Xudong , Huang Mingming , Li Zhiqian , Zeng Xianchun , Wang Rongpin , Shen Guiquan , Yu Hui 
Published: September 2020

Objective:
Application of diffusion tensor imaging (DTI) to explore the changes of FA
value in patients with Parkinson's disease (PD) with mild cognitive impairment.

Methods:
27 patients with PD were divided into PD with mild cognitive impairment (PD-MCI)
group (n = 7) and PD group (n = 20). The original images were processed using voxel-based analysis
(VBA) and tract-based spatial statistics (TBSS).

Results:
The average age of pd-mci group was longer than that of PD group, and the course of disease
was longer than that of PD group. Compared with PD group, the voxel based analysis-fractional
anisotropy (VBA-FA) values of PD-MCI group decreased in the following areas: bilateral frontal
lobe, bilateral temporal lobe, bilateral parietal lobe, bilateral subthalamic nucleus, corpus callosum,
and gyrus cingula. Tract-based spatial statistics-fractional anisotropy (TBSS-FA) values in
PD-MCI group decreased in bilateral corticospinal tract, anterior cingulum, posterior cingulum,
fornix tract, bilateral superior thalamic radiation, corpus callosum(genu, body and splenium), bilateral
uncinate fasciculus, bilateral inferior longitudinal fasciculus, bilateral superior longitudinal fasciculus,
bilateral superior fronto-occipital fasciculus, bilateral inferior fronto-occipital fasciculus,
and bilateral parietal-occipital tracts. The mean age of onset in the PD-MCI group was greater than
that in the PD group, and the disease course was longer than that in the PD group.

Conclusion:
DTI-based VBA and TBSS post-processing methods can detect abnormalities in multiple
brain areas and white matter fiber tracts in PD-MCI patients. Impairment of multiple cerebral
cortex and white matter fiber pathways may be an important causes of cognitive dysfunction in
PD-MCI.
A Review on Hepatoprotective Effects of Some Medicinal Plant Oils
Authors: Daoudi Nour Elhouda , Bouhrim Mohamed , Bnouham Mohamed 
Published: September 2020

Background:
The liver is the second largest organ inside the human body. It can be damaged
by several toxic molecules and medicinal agents taken in overdoses. Indeed, there are some
oils obtained from different herbs that can be used to protect the liver injury.

Objective:
This review aims to give details on some oils that have been tested for their hepatoprotective
effect.

Methods:
We reviewed 79 articles published between 1980 and 2019 in English language using
three databases Sciencedirect, Web of Science and PubMed. So, we have used the keywords related
to hepatoprotective activity: Hepatoprotective, liver disease, plant and oil and we have classified the
plants in alphabetical order as a list containing their scientific and family names, as well as the experimental
assay and the results obtained from these studies.

Results:
As a result, we have described 18 species belonging to 18 families: Altingiaceae, Apiaceae,
Arecaceae, Asteraceae, Cactaceae, Caryocaraceae, Cucurbitaceae, Lauraceae, Leguminoseae, Malvaceae,
Moringaceae, Myrtaceae, Oleaceae, Pinaceae, Ranunculaceae, Rosaceae, Theaceae and Vitaceae.
Among the most common fatty acids present in hepatoprotective oils are palmitic acid, linoleic
acid, oleic acid and stearic acid.

Conclusion:
These oils have shown beneficial properties regarding the hepatoprotective activity.
Construction and Analysis of mRNA and lncRNA Regulatory Networks Reveal the Key Genes Associated with Prostate Cancer Related Fatigue During Localized Radiation Therapy
Authors: Wu Yechen , Gui Yaping , Wu Denglong , Wu Qiang 
Published: September 2020

Background:
Localized radiation therapy is the first-line option for the treatment of nonmetastatic
prostate cancer (PCa). Previous studies revealed that long non-coding RNAs (lncRNAs) had
crucial roles in disease progression. However, the mechanisms of lncRNAs underlying prostate cancerrelated
fatigue remained largely unclear.

Objective:
The present study aimed to uncover the key genes related to PCa related fatigue during localized
radiation therapy by constructing mRNA and lncRNA regulatory networks.

Methods:
We analyzed GSE30174, which included 10 control samples and 40 PCa related fatigue
samples, to identify differently expressed lncRNAs and mRNAs in PCa related fatigue. A proteinprotein
interaction network was constructed to reveal the interactions among mRNAs. Co-expression
network analysis was applied to identify the key lncRNAs and reveal the functions of these lncRNAs in
PCa related fatigue.

Results and Discussion:
This research found 1271 dysregulated mRNAs and 205 dysregulated
lncRNAs in PCa related fatigue using GSE30174. Bioinformatics analysis showed that PCa related fatigue
with mRNAs and lncRNAs were associated with inflammatory response and immune response
related biological processes. Furthermore, we constructed a PPI network and lncRNA co-expression
network related to fatigue in PCa. Of note, we observed that the dysregulated lncRNAs and mRNAs,
such as SEC61A2, ADCY6, LPAR5, COL7A1, ALB, COL1A1, SNHG1, LINC01215, LINC00926,
GNG4, LMO7, and COL4A6, in PCa related fatigue could predict the outcome of PCa patients.

Conclusions:
This research could provide novel mechanisms underlying fatigue and identify new biomarkers
for the prognosis of PCa.
Investigating the Attitudes of Adolescents and Young Adults Towards JUUL: Computational Study Using Twitter Data
Authors: Benson Ryzen , Hu Mengke , Chen Annie T , Nag Subhadeep , Zhu Shu-Hong , Conway Mike 
Published: September 2020

Background
Increases in electronic nicotine delivery system (ENDS) use among high school students from 2017 to 2019 appear to be associated with the increasing popularity of the ENDS device JUUL.

Objective
We employed a content analysis approach in conjunction with natural language processing methods using Twitter data to understand salient themes regarding JUUL use on Twitter, sentiment towards JUUL, and underage JUUL use.

Methods
Between July 2018 and August 2019, 11,556 unique tweets containing a JUUL-related keyword were collected. We manually annotated 4000 tweets for JUUL-related themes of use and sentiment. We used 3 machine learning algorithms to classify positive and negative JUUL sentiments as well as underage JUUL mentions.

Results
Of the annotated tweets, 78.80% (3152/4000) contained a specific mention of JUUL. Only 1.43% (45/3152) of tweets mentioned using JUUL as a method of smoking cessation, and only 6.85% (216/3152) of tweets mentioned the potential health effects of JUUL use. Of the machine learning methods used, the random forest classifier was the best performing algorithm among all 3 classification tasks (ie, positive sentiment, negative sentiment, and underage JUUL mentions).

Conclusions
Our findings suggest that a vast majority of Twitter users are not using JUUL to aid in smoking cessation nor do they mention the potential health benefits or detriments of JUUL use. Using machine learning algorithms to identify tweets containing underage JUUL mentions can support the timely surveillance of JUUL habits and opinions, further assisting youth-targeted public health intervention strategies.
Who is Saying What on Twitter: An Analysis of Messages with References to HIV and HIV Risk Behavior
Authors: Lohmann Sophie 
Published: September 2020

This research aimed to determine the nature of social media discussions about HIV. With the goal of conducting a descriptive analysis, we collected almost 1,000 tweets posted February to September 2015. The sample of tweets included keywords related to HIV or behavioral risk factors (e.g., sex, drug use) and was coded for content (e.g., HIV), behavior change strategies, and message source. Seven percent of tweets concerned HIV/AIDS, which were often referred to as jokes or insults. The majority of tweets coded as behavior change attempts involved attitude change strategies. The majority of the tweets (80%) came from private users (vs. organizations). Different types of sources employed different types of behavior change strategies: For instance, private users, compared to experts or organizations, included more strategies to decrease detrimental attitudes (29% versus 6%, p < .001), and also more strategies to counter myths and misinformation (6% versus 1%, p = .008). In summary, tweets related to HIV/AIDS and associated risk factors frequently use the terms in jokes and insults, come largely from private users, and entail attitudinal and informational strategies. Online health campaigns with clear calls to action and corrections of misinformation may make important contributions to social media conversations about HIV/AIDS.