bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancement Effect of Zn-Arsenazo III Complex for G-quadruplex DNA Stability of Proto-oncogene Promoter Telomeres
Authors: Zou Liyuan , Li Hongbo , Liu Mingbin , Zhao Weihua , Wang Suqin 
Published: November 2019

Background:
Controlling the structure of proto-oncogene telomeres is very important in
antitumor therapy. There are relationships between G-quadruplex DNA and the growth of tumor cell.

Methods:
In this study, spectroscopic, cyclic voltammetry and viscosity methods were employed to
investigate the interaction between Zn-Arsenazo Ⅲ complex and G-quadruplex DNA by using 4S
Green Plus Nucleic Acid Stain as a spectral probe in PBS buffer. The binding ratios were n Arsenazo Ⅲ
: n Zn(Ⅱ) = 5:1 for Zn-Arsenazo Ⅲ complex and n Zn- Arsenazo Ⅲ : n G-quadruplex DNA = 8:1 for Zn-Arsenazo
Ⅲ-G-quadruplex DNA. The bonding constants (Kθ
298.15K=4.44x105 L·mol-1, Kθ
308.15K= 1.00x105
L·mol-1, Kθ
318.15K= 1.04x106 L·mol-1) were obtained by double reciprocal method at different temperatures, Which was found that the interaction between Zn-Arsenazo Ⅲ complex and Gquadruplex
DNA was driven by enthalpy. Furthermore, the research further confirmed that the interaction
mode between Zn-Arsenazo Ⅲ complex and G-quadruplex DNA was a mixed binding
which involved intercalation and non-intercalation interaction.

Results and Conclusion:
Together these findings also have corroborated the application of stabilizing
ligands and intervening with their function for target G-quadruplexes in a cellular context.
Improving Calcium Knowledge and Intake in Young Adults Via Social Media and Text Messages: Randomized Controlled Trial
Authors: Rouf Anika , Nour Monica , Allman-Farinelli Margaret 
Published: November 2019

Background
Calcium is an important nutrient for the attainment of peak bone mass during adolescence and young adulthood. However, these life phases are characterized as hard to reach for health promotion. Social media platforms offer a promising channel as they are relatively low cost but used ubiquitously by youth.

Objective
The aim of the CAlcium Nutrition-Dietary Opportunities (CAN-DO) study was to conduct a randomized controlled trial to test the effectiveness of Facebook alone or with text messaging as channels to deliver a theory-based program to encourage optimal calcium intake.

Methods
The intervention was a 3-arm parallel trial. Young adults aged 18 to 25 years were recruited through university and social media for a 6-week trial. Participants were randomized to 1 of the 3 arms (ie, Facebook posts, Facebook posts plus text messages, and control group that received an electronic leaflet containing information on calcium intake). The primary outcome was change in intake of milk and other calcium-rich foods, and secondary outcomes were knowledge, self-efficacy, motivation, and habit formation concerning calcium-rich foods. Changes were assessed before and after the intervention, and the differences in change between groups were compared using multivariate regression models with multiple imputations for missing data.

Results
A total of 211 participants (64/211, 30.3% males) participated (mean age 21.4 years, SD 2.1) in this study. At the end of the program, no increase in milk intake (odds ratio [OR] 1.51, 95% CI 0.61-3.75 Facebook; OR 1.77, 95% CI 0.74-4.24 Facebook plus text messages; P=.41) nor calcium-rich food was detected (P=.57). There was a significant improvement in knowledge in the Facebook plus text messages group (P<.001), but habit formation improved less than that in the other 2 groups (P=.01). Our results showed a moderate level of engagement with intervention content and positive qualitative feedback from participants.

Conclusions
The CAN-DO study delivered via Facebook (with the additional support of text messages) was found to improve knowledge and was acceptable among young adults. However, further research is needed to better understand social media engagement and how to optimize the program for participants to be sufficiently motivated to increase their intake of calcium-rich foods.

Trial Registration
Australian New Zealand Clinical Trials Registry ACTRN12620000097943; http://www.anzctr.org.au/ACTRN12620000097943.aspx
Librarian role in research library services in Indonesian Institute of Sciences
Authors: Riyanto Slamet , Marlina Ekawati , Triasih Hermin 
Published: November 2019

Introduction.In a research library, researchers are the main players, while . librarians should be the partners in conducting research even though this combination rarely happens. In general, librarians are only involved in a part of research activities as their research assistants to carry out some administrative stuffs, such as distributing questionnaires and sending invitation letters, instead of designing a research plan and/or somequestionnaires or doing data analyses.Data Collection Method. We interviewed librarians in the Center for Political Studies, Research Center for Economic, Center for Science and Technology Development, and Center for Scientific Documentation and Information of Indonesian Institute of Sciences, Jakarta.Data Analyses. Data were analyzed using qualitative analysis methods, through the direct interview, where data categorized by using open coding.Results and Discussions.The results stated that 86.7% of respondents had ever been involved in research activities carried out by the research center in the same or different units. From that result, 53.3% respondents ever engaged research activities up to 5 times in a year. In the other hands, librarians who answer conduct independent research and are often involved in the research are 13% respondents. Some recommendations figured out from this research are (1) a librarian could be a plagiarism examiner for a research proposal, (2) a librarian must be literated in information technologies, (3) a librarian should be involved in examining a literature review of the proposal and writing the manuscripts.Conclusions.The role of a librarian is not just as a research assistant or a data collector but as a research buddy who could help addressing some documentative problems.
IMPROVING STUDENT WRITING ABILITY IN NARRATIVE TEXT THROUGH THINK TALK WRITE METHOD AT TENTH GRADE OF SMK PGRI 3 CIMAHI
Authors: Lisnawati Dina , Elvirasari Diana , Santoso Iman 
Published: November 2019

The purpose of this research was to find out the improvement of students’ writing abilityin writing narrativetext through think talk write method.The design of this research is point out in the experimental class design. This research will compare the think talk write method and ordinary teaching model. The students’ would learn how to write narrative text. The population of this research was the tenth grade of SMKPGRI 3 cimahi. Therefore, the advantages of this research to invented the new teaching model to the students’, it was good for students’ development in teaching and learning English with a new model of teaching. This study uses quasi experimental design, Data from this study collected through pre-test and post-test, in order to find out some of the results that have increased or decreased, The results show an experimental class with the TTW (Think Talk Write) method. The pre-test results were supported by highest score and the lowest with the highest, pre-test score of 85 while the lowest score was 52, and the post-test score was 52 and the post-test score with the highest score of 93, and the lowest 70. With the pre-test and post-test researchers could compare the assessment
Students' Speaking Anxiety in EFL Classroom
Authors: Asysyfa Asysyfa , Handyani Ayu Maulidia , Rizkiani Siska 
Published: November 2019

This study investigated the students’ speaking anxiety in the first grade of vocational high school. It emphasized on the level, the causal factors and the strategy to reduce the anxiety. It applied descriptive qualitative to answer the research questions. The data were obtained through questionnaire and interview. The Foreign Language Classroom Anxiety Scale (FLCAS) questionnaires and interview were administered to 30 students. It was revealed that [a1] the factors that make students feel anxious in speaking in English were lack of preparation, afraid of left behind in understanding the material or what the teacher talks about, afraid of making mistakes, afraid of being laughed by his/her friends, unconfident to spell, pronounce and select the words in English. It was also found that there were eight students in level Relaxed, twelve students in level Mildly Anxious, and ten students in level Anxious. Last, the strategies that students should do to reduce their anxiety are do more preparation before speaking, try to be more confident in saying English words, and pronunciation practice. Keywords: Speaking, Speaking anxiety, EFL Classroom. [a1]It was revealed that
AN ANALYSIS DEIXIS IN RIDWAN KAMIL’S SPEECH AT THE ASIA AFRICA CONFERENCE (KAA)
Authors: Asmarita Aas , Haryudin Acep 
Published: November 2019

The central topics of pragmatics, this study is limited on applying deixis on speech Ridwan Kamil at the Asia Africa Conference (KAA). This research deals with the English deixis. The objectives of this study are to analyze type of deixis and to find out the most dominant type of deixis in “Ridwan Kamil’s speech at Asia Africa Conference (KAA)” on April 24th 2015. This study was conducted by using qualitative approach. From the five type of deixis, in Ridwan Kamil’s speech found that there are three types of deixis, namely person deixis (7 data) time deixis (3 data), and the last is social deixis (1 data). From the analysis of deixis, it was also revealed that person deixis as the most dominant type which was found on speech Ridwan Kamil at the Asia Africa Conference. Keywords: Deixis, Asia Africa Conference (KAA), Speech
Oxidative Stress Induced DNA Damage and Reproductive Toxicity in Male Albino Mice Orally Exposed to Sorbitol
Authors: Alabi Okunola A. , Oladimeji Lanre R. , Sorungbe Adewale A. , Adeoluwa Yetunde M. 
Published: November 2019

Abstract
In this study, the potential DNA damage and reproductive toxicity of sorbitol was investigated using bone marrow micronucleus (MN), sperm morphology, and sperm count in mice. Five doses of 90, 45, 20, 10 and 1 mg/kg/day, defined by allometry, and approximately corresponding to 1.5g, 750mg, 330mg, 165mg and 16mg of sorbitol daily consumption by a 70kg human, respectively, were used. MN analysis showed a dose-dependent induction of micronucleated polychromatic erythrocytes and other nuclear abnormalities across the treatment groups. Assessment of sperm shape showed a significant (p < 0.05) increase in sperm abnormalities with significant (p < 0.05) decrease in mean sperm count in treated groups. The result of the oxidative stress biomarkers showed induction of significant (p < 0.05) increase in liver catalase, MDA and serum ALT and AST activities with concomitant decrease in SOD activities in exposed mice. A significant increase in weight of exposed mice were recorded when compared with the negative control. The results of this study showed the genotoxicity and reproductive effects of sorbitol.
Total Solid Content and Compound Properties from Different Collection Time of Hevea brasiliensis Latex
Authors: Junaidi  , Wijaya Andi , Rachmawan Arief , Andriyanto Mochlisin 
Published: November 2019

Abstract
This study compared the total solid content and compound properties of Hevea rubber latex produced from material collected during different periods. Samples were collected from five trees, with the collection replicated three times with tapping task as replication. Observed parameters included total solid content, vulcanization characteristics, technical and physical properties. The results exhibited that the longer latex flowed, the more total solid content tended to decrease. Results indicate that compound of latex collected 20 minutes (C20), 60 minutes (C60), and 300 minutes (C300) after tapping qualified for SIR 20. Other parameters did not show a significant difference among the three tested compounds. Considering the products requiring high dry rubber content, it is suggested not to blend the late collection with main collected latex.
The Effect of Tractor Driving System Type on its Slip and Rolling Resistance and its Modelling Using Anfis
Authors: Moinar Abdolmajid , Shahgholi Gholamhossein 
Published: November 2019

Abstract
Pulling force required for operations such as tillage is a result of the interaction between the tractor’s wheel drive and soil surface limited by various factors, such as the rolling resistance and slip of the wheel drive. In this research, the traction performance of tractors with different driving systems (four-wheel drive, rear wheel drive, and front wheel drive) was investigated. Test parameters included different tractor forward speeds (1.26, 3.96, and 6.78 km·h−1), tire inflation pressures (170, 200, and 230 kPa), ballast weights (0, 150, and 300 kg), and aforementioned driving systems, as well as required drafts (2, 6, and 10 kN). For each experiment, two indices of slip and rolling resistance were measured. The results of this study showed that the four-wheel-driving system indicated a low slip at similar pulling forces. In order to achieve a low slip, the four-wheel driving system did not necessarily need to add the ballast weight or to reduce the inflation pressure. The four-wheel driving system showed lower rolling resistance than the other two systems. Slip and rolling resistance of wheels were predicted using an adaptive neuro-fuzzy inference system (ANFIS). It was found that ANFIS had a high potential for predicting the slip (R
2 = 0.997) and rolling resistance (R
2 = 0.9893).
Mathematical Modelling of Solar Thermal Collectors and Storages
Authors: Tóth János , Farkas István 
Published: November 2019

Abstract
Block-oriented modelling is a powerful tool in system design. The models developed this way can be used to study various systems, such as solar thermal systems. In the work presented, main goal is to compare different mathematical models of solar thermal devices. The difference in accuracy of such models in respect to the possibilities of a hardware-in-the-loop simulation will be discussed. Two models of solar thermal collectors will be compared and used in a system containing two different heat storages in order to study the behaviour of these models. The tests were carried out in a Simulink based block-oriented environment called SimSolar.
Investigations of the Dynamics of a Four-Element Machine-and-Tractor Aggregate
Authors: Bulgakov Volodymyr , Ivanovs Semjons , Adamchuk Valerii , Antoshchenkov Roman 
Published: November 2019

Abstract
The paper presents a dynamic model of four-element machine-and-tractor designed on the basis of a combined soil-cultivating-sowing aggregate and a tractor with an articulated frame. The pseudo velocity of the first tractor half-frame was considered a generalised coordinate. The control impact upon the tractor was obtained by means of the bending angle of the tractor half-frames. The trajectories and movement speeds of the aggregate elements were calculated as a function of time for the driving mode along a straight-line path and the tractor movement according to the harmonic control law. By means of the measuring system, trajectories of the aggregate elements were obtained. It was established that the movement trajectories of the aggregate elements represent a complex assessment parameter of the mathematical model adequacy of the aggregate plane-parallel movement. There was found a regularity of the aggregate turning radius and the bending angle of the tractor half-frames.
Cultivation of dandelion (Taraxacum erythropodium) on coastal saline land based on the control of salinity and fertilizer
Authors: Wu Zhe , Xue Zhizhong , Li Haishan , Zhang Xiaodong , Wang Xiuping , Lu Xuelin 
Published: November 2019

Abstract
Dandelion (Taraxacum spp.) is a widely distributed weed; in China, however, dandelion has been considered to be a kind of medicinal and edible vegetable in recent years. This transition from weed to vegetable requires corresponding cultivation and management. Thus, the production of dandelion on saline land was conducted based on the evaluation of dandelion salt tolerance. Low soil salt content (< 0.3%) did not significantly affect dandelion growth, and the salt tolerance threshold of dandelion ranged from 0.4% to 0.43% according to the correlation between salt content and morphological and physiological parameters, which was for guiding the preparation of saline land for dandelion field cultivation. Different fertilizer treatments significantly affected the leaf yield of dandelion, and the maximum fresh leaf yield of ~10.5 t ha−1 was obtained when urea was applied in batches at a ratio of 2:2:1 in the sowing, seedling and flowering stages, respectively. This research provided the theoretical and technical support for the cultivation on saline land, laying the foundation for further study of quality control for the cultivation of dandelion on saline land.
Cognitive Pretesting and pretest of the STRAIN questionnaire to elaborate work-related stress of health care staff in Switzerland / Verständlichkeitsprüfung und Pretest des STRAIN-Fragebogens zur Erhebung der Arbeitsbelastung bei Gesundheitsfachpersonen in der Schweiz
Authors: Golz Christoph , Peter Karin Anne , Hahn Sabine 
Published: November 2019

Abstract
The workforce shortage in health care is a major challenge worldwide. In Switzerland, this shortage is not only demographically caused but also due to workload. Adequate measures require a good data basis. The aim of this study is to test instrument specially developed for the health professions to measure work-related stress in practice. Cognitive pretesting was used for the evaluation. Overall, 18 semi-structured single-interviews with nurses and nursing assistants were conducted. In two rounds, the question-answer-process was analysed for 11 questions. The STRAIN questionnaire was then pretested by 17 health professionals. In the first round, 42 problems were identified based on the phases of the “Cognitive Aspects of Survey Methodology”. Of these, 57 % were comprehension problems. This was shown by the polysemantic usage or unknowingness of terms. Further 38 % were problems with the answer categories, such as a missing category or an inappropriate formulation. Further questions were modified through a final pretest. The uniform comprehensibility has been achieved. Due to the questionnaire length, an online tool with a save function should be used. The results of this study are similar to those of comparable studies, which also show the most common problems with understanding. This is due to changes of concepts’ meanings over time and culture. A cognitive pretest is therefore recommended, especially for a heterogeneous target group such as health professions.
Challenges and facilitators for health practitioners and academics engaging in collaborative research and publication: A systematic review / Herausforderungen und Förderfaktoren für gemeinsame Forschung und wissenschaftliche Publikation von Angehörigen verschiedener Gesundheitsberufe aus Praxis und Forschung: ein systematischer Review
Authors: King Lindy , Zlatanovic Tatjana , Gillham David 
Published: November 2019

Abstract

Introduction
While academics are frequently engaged in research activities and subsequent dissemination of results through publication, all too often they occur without health practitioner involvement. While there are contemporary expectations that health practitioners will be active contributors to their discipline’s body of knowledge, many find it difficult to prioritise research involvement given the demands of direct patient care. With this awareness as a central focus, we undertook a literature review to identify the challenges and facilitators that impact on health practitioners and academics working collaboratively on research and publishing their findings in peer-reviewed journals.

Methods
A configurative systematic review was performed with six electronic databases (Proquest, CINAHL, Medline, ScienceDirect, ERIC, SocINDEX) searched for studies from the disciplines of nursing, social work, allied health professions, health management, psychology and sociology. Manual searches were also undertaken to minimise the risk of missed studies. A rigorous search and retrieval process identified 20 relevant studies for inclusion in the review. The studies were first critically appraised then summarised. These steps were followed by thematic synthesis of the findings of the reviewed studies.

Results
Challenges and facilitators to health practitioners and academics working collaboratively on research activities were found to be related to the interplay between practitioners, academics, educational and health institutions and professional demands. The interplay of these factors emerged as complex.

Conclusion
Strategies have been recommended that may encourage active partnerships between institutions, health practitioners and academics enabling greater research collaborations and subsequent increased publication of their combined achievements.
Views of practice owners on intraprofessional cooperation in teams of professionally trained and academic therapists / Sichtweisen von Praxisinhabern/-innen auf die intraprofessionelle Zusammenarbeit in Teams von berufsfachschulisch ausgebildeten und akademisierten Therapeuten/-innen
Authors: Schönfeld Andreas , Luderer Christiane 
Published: November 2019

Abstract

Background
The academisation of the therapy professions occupational therapy, speech therapy and physiotherapy in Germany has created new challenging constellations. Tensions can be seen in the intraprofessional cooperation of professionally qualified employers and academic employees due to identical work contents and equal pay.

Question
How do professionally trained leaders experience the intraprofessional cooperation of professionally trained and academic employees?

Aim
The study describes from the point of view of professionally trained therapists their experiences in their daily work with academic employees in order to derive opportunities, challenges and success factors in intraprofessional cooperation.

Method
A qualitative content analysis with computer support in MAXQDA of n=9 semi-structured focussed interviews from a two-arm cross-sectional study with extern method triangulation is presented. The data are supplemented by n=85 free text entries of two online surveys.

Results
The interviewed leaders welcome academisation because of the promotion of professional stability, social recognition and the advancement of research. In the intradisciplinary cooperation with their academic colleagues there is a predominantly friendly and equal working atmosphere. However, interviewees report a limited creativity of academic employees in practical work, as well as fluctuations with unsatisfying practical commitment due to a low occupational perspective and poor remuneration.

Discussion
While academic employees are eager to expand their practical work, this can only be achieved by providing time and financial resources from practice management. Structural incentives must be provided by more responsibility, extended fields of activity or qualification and performance-related remuneration models in order to retain academic employees in practice.While academic employees are eager to expand their practical work, this can only be achieved by providing time and financial resources from practice management. Structural incentives must be provided by more responsibility, extended fields of activity or qualification and performance-related remuneration models in order to retain academic employees in practice.