bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constraining the formation of authigenic carbonates in a seepage‐affected cold‐water coral mound by lipid biomarkers
Authors: Feenstra Eline Juliette , Birgel Daniel , Heindel Katrin , Wehrmann Laura M. , Jaramillo‐Vogel David , Grobéty Bernard , Frank Norbert , Hancock Leanne G. , Van Rooij David , Peckmann Jörn , Foubert Anneleen 
Published: February 2020

AbstractCold‐water coral (CWC) mounds are build‐ups comprised of coral‐dominated intervals alternating with a mixed carbonate‐siliciclastic matrix. At some locations, CWC mounds are influenced by methane seepage, but the impact of methane on CWC mounds is poorly understood. To constrain the potential impact of methane on CWC mound growth, lipid biomarker investigations were combined with mineralogical and petrographic analyses to investigate the anaerobic oxidation of methane (AOM) and authigenic carbonate formation in sediment from a seep‐affected CWC mound in the Gulf of Cadiz. The occurrence of AOM was confirmed by characteristic lipids found within a semi‐lithified zone (SLZ) consisting of authigenic aragonite, high‐magnesium calcite and calcium‐excess dolomite. The formation of high‐Mg calcite is attributed to AOM, acting as a lithifying agent. Aragonite is only a minor phase. Ca‐excess dolomite in the SLZ and upper parts may be formed by organoclastic sulphate reduction, favouring precipitation by increased alkalinity. The AOM biomarkers in the SLZ include isoprenoid‐based archaeal membrane lipids, such as abundant glycerol dibiphytanyl glycerol tetraethers (GDGTs) dominated by GDGT‐2. The δ13C values of GDGT‐2, measured as ether‐cleaved monocyclic biphytanes, are as low as −100‰ versus V‐PDB. Further, bacterial dialkyl glycerol diethers with two anteiso‐C15 alkyl chains and δ13C values of −81‰ are interpreted as biomarkers of sulphate‐reducing bacteria. The lipid biomarker signatures and mineralogical patterns suggest that anaerobic methane‐oxidizing archaea of the ANME‐1 group thrived in the subsurface at times of slow and diffusive methane seepage. Petrographic analyses revealed that the SLZ was exhumed at some point (e.g. signs of bioerosion of the semi‐lithified sediment), providing a hard substrate for CWC larval settlement. In addition, this work reveals that AOM‐induced semi‐lithification likely played a role in mound stabilization. Lipid biomarker analysis proves to be a powerful tool to disentangle early diagenetic processes induced by microbial metabolisms.
Balanced‐budget rules: Local indeterminacy and bifurcations
Authors: Stockman David R. 
Published: February 2020

AbstractSchmitt‐Grohé and Uribe (1997) illustrate that a balanced‐budget rule can lead to local indeterminacy and sunspot equilibria. I extend their local analysis by using local bifurcation techniques to investigate the possibility of cyclic and sunspot equilibria under a balanced‐budget rule in a neighborhood of a locally determinate steady state. For a class of models, I show the generic existence of two bifurcation steady‐state tax rates: flip and fold. The flip bifurcation implies the existence of 2‐cycles. Furthermore, I show analytically for a large region of the parameter space that this flip bifurcation is supercritical so the 2‐cycles are stable. This finding establishes the existence multiple equilibria and sunspot equilibria in a neighborhood of a locally determinate steady state. I also find there are model parameterizations where the fold bifurcation tax rate is lower than the flip bifurcation tax rate. In these instances, the steady state is a source for tax rates between these bifurcation tax rates. This indicates a qualitatively different type of aggregate instability due to a balanced‐budget rule.
Association of sensory sensitivities and toothbrushing cooperation in autism spectrum disorder
Authors: Khrautieo Tippawan , Srimaneekarn Natchalee , Rirattanapong Praphasri , Smutkeeree Apiwan 
Published: February 2020

AbstractBackgroundSensory over‐responsivity (SOR) is common in autistic spectrum disorder (ASD), and it leads to a more intense response to sensory stimuli.AimTo compare toothbrushing cooperation at home and in a dental office between SOR and sensory not over‐responsivity (SNOR) children with ASD.DesignThis cross‐sectional observational study was conducted with 51 children with ASD aged 4‐17 years. Caregivers assessed each subject's sensory response by completing a back‐translation questionnaire listing eight sensitivities. Subjects who had three or more of the sensitivities were considered SOR subjects. Toothbrushing cooperation in the dental office was recorded on videos. Statistical analysis used the Spearman correlation coefficient, chi‐square test, Fisher's exact test, and Mann‐Whitney U test.ResultsSNOR subjects (n = 10) had significantly higher scores in toothbrushing cooperation at home and in the dental office than did SOR subjects (n = 41) (P < .05). Oral sensitivity was significantly associated with toothbrushing cooperation at home, whereas oral, light, sound, and touch (face) sensitivities were significantly correlated with toothbrushing cooperation in the dental office (P < .05).ConclusionsSOR subjects showed less toothbrushing cooperation than SNOR subjects both at home and in the dental office.
Associations of occupational stress, workplace violence, and organizational support on chronic fatigue syndrome among nurses
Authors: Li Mengyao , Shu Qianyi , Huang Hao , Bo Wen , Wang Lulu , Wu Hui 
Published: February 2020

AbstractAimsChronic fatigue syndrome is an agnogenic disease worldwide. Nurses are at a high risk of chronic fatigue syndrome. However, no research has been done to examine the associations of workplace violence, organizational support, and occupational stress with chronic fatigue syndrome among Chinese nurses. This study aimed to examine effects of these factors on chronic fatigue syndrome in this occupational group.DesignCross‐sectional. All participants voluntarily completed a questionnaire survey.MethodsThe study was conducted in Liaoning province from December 2017–January 2018. Self‐administered questionnaires were distributed to 1,200 nurses, including Effort‐Reward‐Imbalance, Workplace Violence Scale, Survey of Perceived Organizational Support, together with age, gender, marital status, education levels, physical activities, job rank, monthly income, and weekly working hours. Complete responses were obtained from 1,080 (90%) participants. Chronic fatigue syndrome was diagnosed by doctors according to the Centers for Disease Control and Prevention criteria. Multivariable logistic regression was performed to examine these independent risk factors.ResultsThe prevalence of chronic fatigue syndrome was 6.76%. The results of logistic regression analysis showed that nurses who experienced serious higher levels of overcommitment, workplace violence and less organizational support were more likely to be classified as chronic fatigue syndrome.ConclusionThere was a high prevalence of chronic fatigue syndrome. Lower workplace violence, more organizational support and lower overcommitment could be effective resources for reducing chronic fatigue syndrome.ImpactWorkplace violence, organizational support, and occupational stress were related to chronic fatigue syndrome, which helped to explain why Chinese nurses suffered higher prevalence of chronic fatigue syndrome. Overcommitment explained chronic fatigue syndrome better than Effort/Reward Ratio, so intrinsic stress played a more critical role than extrinsic stress in chronic fatigue syndrome. Chinese nurses suffered serious sleep disorders and impairment of concentration and memory. These symptoms might also attribute to serious occupational stress, unsafe and unsupportive working environment. Creating a safe and supportive working environment, relieving intrinsic occupational stress should be considered as an institutional strategy to early prevent chronic fatigue syndrome.
Have pregnancy outcomes improved with the introduction of the International Association of Diabetes and Pregnancy Study Groups criteria in Japan?
Authors: Nakanishi Sayuri , Aoki Shigeru , Kasai Junko , Shindo Ryosuke , Saigusa Yusuke , Miyagi Etsuko 
Published: February 2020

AbstractAims/IntroductionThis study aimed to investigate the effects of the introduction of the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria for diagnosing gestational diabetes mellitus (GDM) on maternal and neonatal outcomes in Japan.Materials and MethodsThis was a retrospective study carried out at a tertiary center in Japan. Previously in Japan, GDM was diagnosed if two or more of the following Japan Society of Obstetrics and Gynecology (JSOG) criteria were met: fasting plasma glucose ≥100 mg/dL, 1‐h value ≥180 mg/dL or 2‐h value ≥150 mg/dL on the 75‐g oral glucose tolerance. Since 2010, GDM has been diagnosed if one or more of the following IADPSG criteria are met: fasting plasma glucose ≥92 mg/dL, 1‐h value ≥180 mg/dL or 2‐h value ≥153 mg/dL on the 75‐g oral glucose tolerance. We compared the pregnancy outcomes of all pregnant women with singleton pregnancies after 22 weeks’ gestation at our hospital before (JSOG period) and after (IADPSG period) the IADPSG criteria were adopted.ResultsThere were 3,912 women in the JSOG period and 4,772 in the IADPSG period. GDM prevalence increased from 2.9% in the JSOG period to 13% in the IADPSG period (P < 0.001). No significant differences between the groups were found in rates of macrosomia, or large for gestational age, and no significant differences were found in birthweight. The neonatal hypoglycemia rate and neonatal intensive care unit admission rate were significantly lower in the IADPSG period (adjusted odds ratio 0.51 and 0.78, respectively).ConclusionsIntroduction of the IADPSG criteria for diagnosing GDM increased GDM diagnosis frequency fourfold, but reduced neonatal intensive care unit admission and neonatal hypoglycemia rates significantly.
Clinical Predictors of Intracranial Bleeding in Older Adults Who Have Fallen: A Cohort Study
Authors: de Wit Kerstin , Parpia Sameer , Varner Catherine , Worster Andrew , McLeod Shelley , Clayton Natasha , Kearon Clive , Mercuri Mathew 
Published: February 2020

OBJECTIVESEmergency department (ED) visits among older adults are frequently instigated by a fall at home. Some of these patients develop intracranial bleeding. The aim of this study was to identify the incidence of intracranial bleeding and the associated clinical features in older adults who present to the ED after falling.DESIGNProspective cohort study.SETTINGThree Canadian EDs.PARTICIPANTSA total of 2 176 patients age 65 years or older who presented to the ED with a fall were assessed, and 1753 were included. Inclusion criteria were a fall on level ground, off a bed, chair, or toilet, or from one or two steps within 48 hours.MEASUREMENTSEmergency physicians recorded predefined clinical findings on initial assessment. The primary outcome was intracranial bleeding, diagnosed either by computed tomography at the index visit or within 42 days. Associations between baseline clinical findings and the presence of intracranial bleeding were assessed with multivariable logistic regression.RESULTSA total of 1753 patients (median age = 82 y) were enrolled, of whom 39% were male, 35% were on antiplatelet therapy, and 25% were on an anticoagulant. The incidence of intracranial bleeding was 5.0% (95% confidence interval [CI] = 4.1‐6.1). Overall, 76 patients were diagnosed at the index ED visit, and 12 were diagnosed during follow‐up. Multivariable regression identified four clinical variables that were independently associated with intracranial bleeding: new abnormalities on neurologic examination (odds ratio [OR] = 4.4; 95% CI = 2.4‐8.1), bruise or laceration on the head (OR = 4.3; 95% CI = 2.7‐7.0), chronic kidney disease (OR = 2.4; 95% CI = 1.3‐4.6), and reduced Glasgow Coma Scale from normal (OR = 1.9; 95% CI = 1.0‐3.4).CONCLUSIONThe incidence of intracranial bleeding in our study was 5.0%. We found significant associations between intracranial bleeding and four simple clinical variables. We did not find significant associations between intracranial bleeding and antiplatelet or anticoagulant use. J Am Geriatr Soc 68:970–976, 2020
Brassinosteroids regulate outer ovule integument growth in part via the control of INNER NO OUTER by BRASSINOZOLE‐RESISTANT family transcription factors
Authors: Jia Dandan , Chen Lian‐Ge , Yin Guimin , Yang Xiaorui , Gao Zhihua , Guo Yi , Sun Yu , Tang Wenqiang 
Published: February 2020

AbstractBrassinosteroids (BRs) play important roles in regulating plant reproductive processes. BR signaling or BR biosynthesis null mutants do not produce seeds under natural conditions, but the molecular mechanism underlying this infertility is poorly understood. In this study, we report that outer integument growth and embryo sac development were impaired in the ovules of the Arabidopsis thaliana BR receptor null mutant bri1‐116. Gene expression and RNA‐seq analyses showed that the expression of INNER NO OUTER (INO), an essential regulator of outer integument growth, was significantly reduced in the bri1‐116 mutant. Increased INO expression due to overexpression or increased transcriptional activity of BRASSINAZOLE‐RESISTANT 1 (BZR1) in the mutant alleviated the outer integument growth defect in bri1‐116 ovules, suggesting that BRs regulate outer integument growth partially via BZR1‐mediated transcriptional regulation of INO. Meanwhile, INO expression in bzr‐h, a null mutant for all BZR1 family genes, was barely detectable; and the outer integument of bzr‐h ovules had much more severe growth defects than those of the bri1‐116 mutant. Together, our findings establish a new role for BRs in regulating ovule development and suggest that BZR1 family transcription factors might regulate outer integument growth through both BRI1‐dependent and BRI1‐independent pathways.
A randomized double‐blind trial evaluating the efficacy and tolerability of topical body treatment with TriHex Technology® combined with abdomen cryolipolysis or radiofrequency procedures
Authors: Moradi Amir , Poehler Jeanette , Bell Michaela 
Published: February 2020

AbstractBackgroundNonsurgical fat reduction procedures using cryolipolysis and radiofrequency are among the most popular noninvasive aesthetic procedures. In a previous study, TransFORM Body Treatment (TFB) with TriHex Technology® (ALASTIN® Skincare) improved the contour and reduced skin laxity following cryolipolysis of the arms. This product is formulated using a combination of peptides and other active ingredients designed to stimulate the autophagic breakdown of lipid droplets and expedite the apoptotic process after fat reduction procedures.AimsTo assess the changes in abdominal volume after application of TFB for 12 weeks following cryolipolysis and radiofrequency procedures.MethodsFollowing abdominal cryolipolysis or radiofrequency therapy, the subjects (N = 15) received TFB product and placebo and were randomly assigned to apply to the right or left sides of the abdomen for 12 weeks. Using 3‐dimensional digital imaging analysis, subjects were evaluated at 4, 8, and 12 weeks posttreatment.ResultsTopical TFB resulted in increased volume loss, which was greater than that for placebo at weeks 4 (P = .0511), 8 (P = .0238), and 12 (P = .0078), respectively, and statistically significant at weeks 8 and 12. There were no reported adverse events.ConclusionIn this study, Topical application of TFB significantly increased adipose volume loss and improved clinical outcomes of nonsurgical fat reduction procedures.
CLARIFYING THE NATURE OF THE HECKMAN CURVE
Authors: Rea David , Burton Tony 
Published: February 2020

AbstractIn response to our paper, we understand that James Heckman communicated to the journal Editors states that the Heckman Curve does not describe how the average return on investment of programs differs by the age of recipients. This clarification is useful as many people in the policy community have understood the Heckman Curve in this manner.
Shaping the mitochondrial inner membrane in health and disease
Authors: Colina‐Tenorio L. , Horten P. , Pfanner N. , Rampelt H. 
Published: February 2020

AbstractMitochondria play central roles in cellular energetics, metabolism and signalling. Efficient respiration, mitochondrial quality control, apoptosis and inheritance of mitochondrial DNA depend on the proper architecture of the mitochondrial membranes and a dynamic remodelling of inner membrane cristae. Defects in mitochondrial architecture can result in severe human diseases affecting predominantly the nervous system and the heart. Inner membrane morphology is generated and maintained in particular by the mitochondrial contact site and cristae organizing system (MICOS), the F1Fo‐ATP synthase, the fusion protein OPA1/Mgm1 and the nonbilayer‐forming phospholipids cardiolipin and phosphatidylethanolamine. These protein complexes and phospholipids are embedded in a network of functional interactions. They communicate with each other and additional factors, enabling them to balance different aspects of cristae biogenesis and to dynamically remodel the inner mitochondrial membrane. Genetic alterations disturbing these membrane‐shaping factors can lead to human pathologies including fatal encephalopathy, dominant optic atrophy, Leigh syndrome, Parkinson's disease and Barth syndrome.
Rallying the Troops and Defending against Sanctions: A Government Body Breaking Decision‐Making Rules to Fund Entrepreneurial Ventures
Authors: Shepherd Dean A. , Johansson Jeaneth , Malmström Malin , Wincent Joakim 
Published: February 2020

AbstractCritical to top management’s organizing efforts are the formal rules for how organizational members are to make decisions. However, employees can break top management’s decision‐making rules. Although scholars have investigated rule breaking at the individual and group levels of analysis, research is needed into how members come together as a group to break an organization’s decision‐making rules, and how groups’ rule breaking persists. To address this important research gap, we draw from a real‐time qualitative investigation of both the breaking and following of decision‐making rules to develop a group model that: (1) explains how an individual can trigger his or her group to break decision‐making rules to generate perceived benefits for the group and/or others external to the organization, (2) provides insights into the mechanisms by which rule breaking persists, and (3) highlights the norms of developing and perpetuating groups’ breaking decision‐making rules.
Effect of brain training through visual mirror feedback, action observation and motor imagery on orofacial sensorimotor variables: A single‐blind randomized controlled trial
Authors: La Touche Roy , Herranz‐Gómez Aida , Destenay Laura , Gey‐Seedorf Ingrid , Cuenca‐Martínez Ferran , Paris‐Alemany Alba , Suso‐Martí Luis 
Published: February 2020

AbstractObjectivesThe main objective was to evaluate the effects of action observation (AO), visual mirror feedback (VMF) and motor imagery (MI), combined with an oro‐facial exercise programme, on sensorimotor variables in asymptomatic participants.MethodsWe designed a randomised, single‐blind, controlled trial that included 52 asymptomatic participants who were randomly assigned to 4 groups, 13 to each of the VMF, MI and AO groups and 13 to the control group (CG), which only performed the exercise programme. The primary outcomes were pain pressure sensitivity and tongue muscle strength. The secondary outcomes were maximum mouth opening, tongue length and the ability to generate mental motor images. Each group underwent a 3‐session intervention using their respective exercise. Measurements were performed before starting the intervention and after each of the 3 sessions (pre, mid1, mid2 and post).ResultsANOVA revealed significant changes in PPTs in the masseter muscle region in the MI and AO groups in the pre‐post and mid1‐post changes. ANOVA revealed significant differences in tongue muscle strength in the anterior direction only in the AO group in the pre‐mid2 and pre‐post changes.ConclusionsAO and MI, in conjunction with exercise, could induce changes in PPTs for the masseter muscle. In addition, only AO produced changes in tongue muscle strength. More research is needed to determine the role of brain representation techniques in the oro‐facial region and transferring this exercise to the rehabilitation setting.
Effect of air temperature on growth performance, apparent digestibilities, rumen fermentation and serum metabolites in Altay and Hu lambs
Authors: Zhou Jianwei , Ji Kaixi , Liu Hu , Zhang Yunsheng , Degen Abraham Allan , Jiao Dan , Wang Wenqiang , Xie Zhongkui , Wang Xinhua , Zhou Ping , Yang Guo 
Published: February 2020

AbstractFat‐tailed Altay sheep are indigenous to the Altay prefecture and well adapted to severe cold and sparse pasture of poor quality. Hu sheep were introduced to this region in the 1970s and are raised mainly in feedlots. We hypothesized that the dietary energy utilization would differ between breeds and predicted that Altay sheep would be more efficient than Hu sheep, in particular at a low air temperature. To test this prediction, we examined growth performance, apparent digestibilities, rumen fermentation and serum metabolites in Altay (32 ± 2.6 kg) and Hu sheep (31 ± 2.7 kg) at air temperatures of −5 and 20°C. Average daily gain (ADG), feed and metabolizable energy intakes were greater in Altay than in Hu sheep (p < .01), and all were greater at −5°C than 20°C (p < .01). Body mass gain‐to‐feed intake ratio was higher in Altay than in Hu sheep (p < .001), but was not affected by air temperature (p > .10). Rumen total volatile fatty acid (VFA) concentration was greater in Hu than in Altay sheep (p < .05) and was greater at 20°C than at −5°C (p < .05), while rumen microbial protein concentration was greater in Altay than in Hu sheep (p < .05). Rectal temperature was higher at −5°C than 20°C (p < .05) and was similar between breeds (p > .05). Serum glucose, non‐esterified fatty acid (NEFA) and urea‐N concentrations were higher in Hu than in Altay sheep (p < .05). It was concluded that Altay sheep are better able to cope with poor quality diets as they had higher digestibility of nutrients, ADG and body mass gain‐to‐feed intake ratio than Hu sheep.