bluuebunny/crossref_metadata_2025_split huggingface dataset:
90 Growth and carcass characteristics of ram, wether, and short-scrotum lambs: year 2
Authors: Schoenian Susan , Semler Jeff , Bennett Mary Beth , Anderson Chris , Grev Amanda , Perdue Maegan 
Published: November 2020

Abstract
This was the second year of a study comparing the growth and carcass characteristics of (intact) ram, wether, and short-scrotum lambs from a commercial sheep dairy in Maryland. East Friesian x Lacaune lambs were left intact (RAM, n = 21), castrated (WETHER, n = 25), or made short-scrotum (SS, n = 18). All banding of WETHER and SS lambs was done by d 10. When the lambs averaged 65±17 d and 44.5±10.6 lbs., they were transported to the Western Maryland Research & Education Center, where they grazed cool season pastures and were supplemented with grain (3 lb/d) for 107 d, before being harvested to collect carcass data. Data were analyzed using the MIXED procedure of SAS, with statistical significance set at P ≤ 0.05. Fixed effects included sex and birth type; starting weight was included as a covariate. There was an effect of birth type on final BW, ADG, HCW, CCW, and body wall thickness (BWT), favoring twin-born lambs. RAM and SS lambs had heavier final BW (P &lt; 0.0001) and ADG (P &lt; 0.0001) than WETHER lambs. RAM lambs had heavier hot (P &lt; 0.01) and cold carcass (P &lt; 0.005) weights than WETHER lambs; SS lambs were intermediate. Dressing percentage was higher (P &lt; 0.004) for WETHER lambs and similar for RAM and SS lambs. RAM and SS lambs had larger REA than WETHER lambs (P &lt; 0.03), but not when adjusted to a common weight (P &lt; 0.71). WETHER lambs produced the fattest carcasses, as evidenced by greater BF (3.8±0.2 mm) than RAM and SS lambs (2.2±0.2 mm and 2.7±0.2 mm, respectively). Sex did not influence BWT, KPH, or leg conformation score. RAM lambs yielded a higher percentage of BCTRC (49.9±0.2%) than WETHER lambs (49.1±0.2%); SS lambs were intermediate (49.6±0.3%). For the second year in a row, RAM and SS lambs demonstrated superior growth and carcass composition compared to WETHER lambs.
170 The effects of supplementing a chelated mineral containing Ascophyllum nodosum on intake and performance of creep-fed hair lambs
Authors: Romo Victoria , Boyd Jamie A 
Published: November 2020

Abstract
The objective of this study was to determine the effect of two commercial mineral supplements on ewes/lamb pairs DMI and ADG. All ewes prior to lambing were maintained a sheep pellet formulated for no mineral, vitamin, or probiotic content at a rate of 2% body weight, ad libitum Bermuda hay, and ad libitum access to the control mineral supplement. Ewe/lamb pairs were randomly assigned based on twining and parity to study groups four days post-lambing. The treatment (TRT) group had 12 ewes/18 lambs, and a control (CNTRL) group had 11 ewes/17 lambs, and was conducted over 6wks. Lambs in both groups were offered ad libitum alfalfa via a creep feeding gate. The TRT group received a commercial chelated mineral mix that included Ascophyllum nodosum seaweed extract in the blend and the CNTRL received a commercial non-chelated mineral without seaweed extract. Chelated minerals were Cu, Mn, and Zn. Daily feed and ort samples were collected 2x week and dried at 55℃ for analysis. Feed was adjusted daily to maintain a 3–5% refusal rate. Samples were compiled by week and analyzed for DM, Ash, aNDF, aADF, EE, and CP. Blood samples were collected from a subset of 7 ewes per group, 3x during the study (wk1, wk3, wk6) for later trace mineral analysis (Co, Cu, Fe, Mn, Mo, Se). Results indicate a significant difference in mineral DMI between groups (P = 0.03), but no significant impact on DMI of Bermuda or alfalfa. ADG for lambs was numerically increased 0.25±0.01 TRT versus 0.23±0.01 kg CNTRL but was not statistically significant (P = 0.18). No significant differences in trace mineral levels between groups or over time was seen. All mineral levels were in the normal range for both groups. It appears the addition of the chelated mineral with Ascophyllum nodosum seaweed extract did not improve ADG or DMI, but the results of this study were potentially affected by severe weather conditions. Further study is needed under more favorable conditions to confirm product impacts in ewe/lamb pairs.
165 The effects of feeding lasalocid in combination with zeranol implants on performance and carcass traits in hair sheep
Authors: Lippy Brittany A , Wilson Blake K , Fitch Jerry , Mafi Gretchen G , Crosswhite Justin 
Published: November 2020

Abstract
The objective of this experiment was to determine the effects of dietary inclusion of lasalocid in combination with zeranol implants on the performance and carcass characteristics of hair sheep. Thirty wether hair lambs (BW = 25.8 + 4.6 kg) were stratified by BW and BCS and randomly assigned to 1 of 2 experimental treatments in a randomized complete block design. The treatments included no implant or ionophore (CON); and the experimental treatment, receiving the ionophore lasalocid (Bovatec® 91; Zoetis, Kalamazoo, MI) and anabolic zeranol implants (Ralgro®; MSD Animal Health, Spartan, RSA; LZ). Lambs on the LZ treatment received 12 mg of zeranol on d 0, 56, and 112, unless lambs were harvested prior to day 112, and consumed an average of 35 mg per day of lasalocid. Lambs had ad libitum access to feed and water throughout the experiment and were housed in individual, slatted floor pens. Performance data were collected on d 0, 14, 28, 56, 84, and at harvest. After d 84, harvest dates were selected and lambs were harvested by block based on proximity to ideal harvest weight and fat thickness. Lasalocid in the diet combined with zeranol implants increased final BW by 14.2% in comparison to CON (P &lt; 0.01). Overall ADG was increased by 36.2% (P &lt; 0.01), and overall G:F was improved by 24.4% for LZ when compared to CON (P = 0.01). There was no difference in overall DMI between treatments (P = 0.13). Hot carcass weight (HCW; P &lt; 0.01), and loin eye area (LEA; P &lt; 0.01) were also greater for the LZ treatment. Dietary inclusion of lasalocid in combination with zeranol implants improved overall BW, ADG, and feed efficiency as well as HCW and LEA in hair sheep.
171 The effects of supplementing a chelated mineral containing Ascophyllum nodosum on intake and performance of creep-fed hair lambs
Authors: Romo Victoria , Boyd Jamie A 
Published: November 2020

Abstract
The objective of this study was to determine the effect of two commercial mineral supplements on ewes/lamb pairs DMI and ADG. All ewes prior to lambing were maintained a sheep pellet formulated for no mineral, vitamin, or probiotic content at a rate of 2% body weight, ad libitum Bermuda hay, and ad libitum access to the control mineral supplement. Ewe/lamb pairs were randomly assigned based on twining and parity to study groups four days post-lambing. The treatment (TRT) group had 12 ewes/18 lambs, and a control (CNTRL) group had 11 ewes/17 lambs, and was conducted over 6wks. Lambs in both groups were offered ad libitum alfalfa via a creep feeding gate. The TRT group received a commercial chelated mineral mix that included Ascophyllum nodosum seaweed extract in the blend and the CNTRL received a commercial non-chelated mineral without seaweed extract. Chelated minerals were Cu, Mn, and Zn. Daily feed and ort samples were collected 2x week and dried at 55℃ for analysis. Feed was adjusted daily to maintain a 3–5% refusal rate. Samples were compiled by week and analyzed for DM, Ash, aNDF, aADF, EE, and CP. Blood samples were collected from a subset of 7 ewes per group, 3x during the study (wk1, wk3, wk6) for later trace mineral analysis (Co, Cu, Fe, Mn, Mo, Se). Results indicate a significant difference in mineral DMI between groups (P = 0.03), but no significant impact on DMI of Bermuda or alfalfa. ADG for lambs was numerically increased 0.25±0.01 TRT versus 0.23±0.01 kg CNTRL but was not statistically significant (P = 0.18). No significant differences in trace mineral levels between groups or over time were seen. All mineral levels were in the normal range for both groups. It appears the addition of the chelated mineral with Ascophyllum nodosum seaweed extract did not improve ADG or DMI, but the results of this study were potentially affected by severe weather conditions. Further study is needed under more favorable conditions to confirm product impacts in ewe/lamb pairs.
74 Epigenetic marks within the swine placenta are differentially expressed due to season
Authors: Cheek Robin , Rempel Lea A , Miles Jeremy 
Published: November 2020

Abstract
The objective of the current project was to validate expression of known chromatin modification genes and assess downstream targets in d45 swine placenta derived from seasonal semen collections and breedings and semen storage. Six treatment groups were developed based upon; season of semen collection (cool or warm), storage of semen (cooled-extended or cryopreserved), and season of breeding (summer or winter) with 8 litters per group as follows: 1) cool/cooled-extended/winter, 2) cool/cryopreserved/winter, 3) warm/cryopreserved/winter, 4) warm/cooled-extended/summer, 5) warm/cooled-extended/summer, and 6) cool/cryopreserved/summer. RNA was extracted from the placenta of a small, medium, and large fetus from each litter, pooled by litter, reverse transcribed, and used for qPCR. Three genes; ATF2, ASH2L, and SMYD3, were validated. Downstream gene targets, ILIB and NANOG, were also tested. Interactions and main effects were tested using the mixed procedure of SAS with boar as a random effect. Placental ASH2L had a tendency for increased expression from summer breedings (P &gt; 0.05), similar to previous findings using a different expression platform. Placental expression of ATF2 was greatest (P &lt; 0.05) from placenta derived by summer breedings. A downstream target of ATF2, ILIB, had greater (P &lt; 0.05) placental expression from summer breedings and semen that was cooled-extended as compared to cryopreserved (P &lt; 0.05). Validation of placental expression of SMYD3 was greater from cooled-extended semen in contrast to cryopreserved semen (P &lt; 0.05). These data were unexpected, as previously we determined a difference by breeding season only. However, NANOG, downstream of SMYD3, had greater placental expression from summer breedings (P &lt; 0.05). The current study validated previous results indicating chromatin modification genes were primarily influenced predominantly by breeding season and to a lesser extent, semen storage techniques. Downstream targets were also influenced by breeding season likely influencing prenatal development. These data support epigenetic modifications persist, even though modern swine systems regulate and control temperature and lighting.
48 Effect of Zelnate administered at initial processing in high-risk, newly received beef calves on performance and morbidity
Authors: Martin Brady E , Cauble Reagan N , Kegley Elizabeth , Powell Jermey G 
Published: November 2020

Abstract
The objective of this study was to investigate the effects of Zelnate, a DNA immunostimulant, administered to calves (n = 261; BW 253 ± 4.0 kg) upon arrival, on morbidity and mortality, growth performance, and producer costs. Crossbred male beef calves (steers and bulls) were acquired from multiple auction markets and transported to the University of Arkansas stocker unit for a 42-d backgrounding period. Calves were randomly allocated to chute side into treatment groups: 1) Control (CON) in which no immunostimulant was administered or 2) Zelnate (ZEL), DNA immunostimulant administered. Animals were checked daily for signs of morbidity and treated with preplanned antibiotics. Records for morbidity and mortality were kept in addition to body temperature, clinical score, and body weight at the time of treatment. Data were analyzed using the GLIMMIX procedures of SAS. Significance was declared at P &lt; 0.05 and tendencies were observed between 0.05 ≤ P &lt; 0.10. No animals died during the duration of this study, however, Zelnate treated calves tended (P = 0.09) to have a lower relapse rate compared to control calves. Average daily gain was similar (P = 0.60) between the two treatment groups. This study also indicated that the treatment cost (Zelnate plus antibiotics) for the Zelnate group was more expensive than the cost to treat the control group (P &lt; 0.01). Overall, our findings indicate that Zelnate administered upon arrival to high risk calves did not improve morbidity rates and respiratory treatment or affect performance, however it did increase costs by $9.24 per calf. Based upon these results, Zelnate does not appear to be an effective therapy for BRD when given upon arrival.
104 Impacts of Phosphorus Intake on Beef Heifer Growth Performance and Reproductive Tract Scores
Authors: Hilfiker Hailey , Kegley Elizabeth , Rorie Rick , Hornsby Pete A , Reynolds Jana , Shoulders Ben P , Cauble Reagan N , Powell Jermey G 
Published: November 2020

Abstract
This study aims to examine the effects of phosphorus intake on beef heifer growth performance and conception rates. In Northwest Arkansas, there has been an increase in phosphorus concentrations in soil where livestock manures have been repeatedly applied. Consequently, forages grown on soils high in phosphorus tend to contain high amounts of the mineral itself. This has led many to question whether it is necessary to supplement phosphorus in areas where concentrations may be higher. In this study, crossbred Angus heifers (n = 72), approximately 30 d after weaning, were stratified by body weight (average initial weight 251 ± 3.9 kg) and allocated randomly into 8 groups. Groups were assigned randomly to 1 of 2 treatments. Treatments were delivered through either 1) a free-choice-mineral mix that contained no supplemental phosphorus (CON), or 2) a free-choice-mineral mix with 4% supplemental phosphorus and identical concentrations of other supplemental minerals (4PMIN). Heifers grazed 2.42 ha mixed grass pastures with a history of livestock manure application and were supplemented with soy hulls (0.5% of body weight) daily. Data were analyzed using the mixed procedures of SAS with group as the experimental unit. Total mineral intake through d 112 did not differ (P = 0.55) between treatments. On d 112, any heifers &gt; 273 kg body weight (n = 58) had an ultrasound evaluation of their reproductive tract. Reproductive tract score (1, infantile, to 5, corpus luteum present) did not differ (P = 0.65) due to treatment. Body weights were not different (P = 0.78) on d 112, 301 ± 5.0 kg and 299 ± 5.0 kg for CON and 4PMIN, respectively. When grazing pastures with a history of livestock manure application, levels of supplemental phosphorus in the free choice mineral did not affect heifer growth performance and reproductive tract scores.
153 The Effect of Nerve Growth Factor Beta on Embryonic Cleavage Rates
Authors: Jones Kayla 
Published: November 2020

Abstract
Nerve growth factor (NGF) beta is a seminal plasma protein that has been associated with sire conception rates in cattle. Previous research showed that the administration of NGFβ, via culture media, to cows resulted in improved conceptus development. Though this finding was thought to be an indirect effect of improved corpus luteum (CL) function, questions raised if NGFβ could act directly on the embryo to promote development. This work seeks to determine the effect of NGFβ supplementation during in-vitro fertilization (IVF) on cleavage and blastocyst rates. How does the administration of NGFβ in culture media affect cleavage and blastocyst rates during in-vitro fertilization? Abattoir-derived bovine ovaries were used for recovery of cumulus-oocyte complexes (COC). Selected COC were placed in the maturation medium. Expanded COC were inseminated with frozen-thawed spermatozoa, and IVF media was supplemented with either 0 ng/mL or 100 ng/mL NGF. Presumptive zygotes were transferred to development medium in a tri-gas chamber with 5% CO2, 5% O2, and 90% N2 in a humidified atmosphere at 39°C, mimicking the bovine uterine climate, until 8 days. Treatment with NGFβ increased the percentage of cleaved embryos at 48 hours and the percentage of hatched embryos at 8 days per oocyte. Treatment of NGFβ did not alter the percentage of blastocysts per cleaved embryo or the percentage of hatched blastocysts. These results show that the NGFβ can act directly on the embryo during fertilization to alter embryonic development, specifically embryonic cleavage rates. Future in vivo studies should assess the downstream effects of NGF treatment on conception rates in cattle.
The effect of hormones on an uncommon breast disorder pseudoangiomatous stromal hyperplasia: a case report and literature review
Authors: Hattingh Genevieve , Ibrahim Mariam , Robinson Thomas , Shah Ajay 
Published: November 2020

Abstract
Pseudoangiomatous stromal hyperplasia (PASH) is a benign proliferation of the breast, with few cases reported to date. While the etiology of the disease is uncertain, a prevailing theory is that PASH is hormonally responsive, especially in the presence of progesterone. Literature review shows a correlation between PASH development and oral contraceptive pill (OCP) use. We report a case of a 28-year-old autistic female who underwent excision of palpable bilateral breast masses where the histology of the left breast mass identified as PASH. Our patient had a history of multiple medications including OCPs and cytochrome p450 inhibitors that could lead to an increase in progesterone levels. Thus, supporting a theory that medications, in addition to OCPs, may lead to an increased occurrence of PASH in pre-menopausal women.
Dermointegration in the exposed titanium cranioplasty: a possible protective phenomenon
Authors: Zhang Steven Liben , Lee Hanjing , Cai Elijah Zhengyang , Yap Yan Lin , Yeo Tseng Tsai , Lim Thiam Chye , Tan Char Loo , Lim Jane 
Published: November 2020

Abstract
Implant exposure is a known complication of titanium mesh cranioplasty and is usually managed by implant removal and/or exchange. We describe a case of exposed titanium mesh cranioplasty which was managed with implant exchange and bipedicled flap coverage, and showcase an interesting phenomenon of full-thickness skin present beneath the exposed mesh. This was confirmed on histopathology, which showed the presence of dermal appendages including pilosebaceous units and eccrine glands. We postulate that the mechanism behind this phenomenon involves islands of viable skin ‘dropping’ between holes in the mesh and coalescing beneath the exposed implant, as suggested by histopathology findings of nodular protrusions and varying degrees of epidermal hyperplasia. This protects the underlying dura from external infection. We propose for this phenomenon to be called dermointegration. Our findings suggest that similar cases, particularly patients who are not fit for general anaesthesia, may potentially be managed with a more conservative approach.
God Bothering Beckett
Authors: Conti Christopher 
Published: November 2020

Abstract
In this article I consider the bearing of theology on Samuel Beckett’s work in terms of what he called ‘the shape’ of the idea. At the heart of Beckett’s negative aesthetic program is the relation of art to truth. The Beckettian subject and object are the remnants of a denarration that foregrounds the pains his narrators endure on their quest for aseity or inexistence. The narrative struggle to tell a story that cannot be told without falsifying it entails a relation to the absolute centring on the experience of incomprehensibility and pain. In Beckett, God can no more come to expression than the self, making the connection between the two impossibilities all but inescapable.
Enhanced Lidov–Kozai migration and the formation of the transiting giant planet WD 1856+534 b
Authors: O’Connor Christopher E , Liu Bin , Lai Dong 
Published: November 2020

ABSTRACT
We investigate the possible origin of the transiting giant planet WD 1856+534 b, the first strong exoplanet candidate orbiting a white dwarf, through high-eccentricity migration (HEM) driven by the Lidov–Kozai (LK) effect. The host system’s overall architecture is a hierarchical quadruple in the ‘2 + 2’ configuration, owing to the presence of a tertiary companion system of two M-dwarfs. We show that a secular inclination resonance in 2 + 2 systems can significantly broaden the LK window for extreme eccentricity excitation (e ≳ 0.999), allowing the giant planet to migrate for a wide range of initial orbital inclinations. Octupole effects can also contribute to the broadening of this ‘extreme’ LK window. By requiring that perturbations from the companion stars be able to overcome short-range forces and excite the planet’s eccentricity to e ≃ 1, we obtain an absolute limit of $a_{1} \gtrsim 8 \, \mathrm{au}\, (a_{3} / 1500 \, \mathrm{au})^{6/7}$ for the planet’s semimajor axis just before migration (where a3 is the semimajor axis of the ‘outer’ orbit). We suggest that, to achieve a wide LK window through the 2 + 2 resonance, WD 1856 b likely migrated from $30 \, \mathrm{au}\lesssim a_{1} \lesssim 60 \, \mathrm{au}$, corresponding to ∼10–$20 \, \mathrm{au}$ during the host’s main-sequence phase. We discuss possible difficulties of all flavours of HEM affecting the occurrence rate of short-period giant planets around white dwarfs.
Premature ovarian ageing following heterozygous loss of Senataxin
Authors: Subramanian G N , Lavin M , Homer H A 
Published: November 2020

Abstract
Premature loss of ovarian activity before 40 years of age is known as primary ovarian insufficiency (POI) and occurs in ∼1% of women. A more subtle decline in ovarian activity, known as premature ovarian ageing (POA), occurs in ∼10% of women. Despite the high prevalence of POA, very little is known regarding its genetic causation. Senataxin (SETX) is an RNA/DNA helicase involved in repair of oxidative stress-induced DNA damage. Homozygous mutation of SETX leads to the neurodegenerative disorder, ataxia oculomotor apraxia type 2 (AOA2). There have been reports of POI in AOA2 females suggesting a link between SETX and ovarian ageing. Here, we studied female mice lacking either one (Setx+/−) or both (Setx−/−) copies of SETX over a 12- to 14-month period. We find that DNA damage is increased in oocytes from 8-month-old Setx+/− and Setx−/− females compared with Setx+/+ oocytes leading to a marked reduction in all classes of ovarian follicles at least 4 months earlier than typically occurs in female mice. Furthermore, during a 12-month long mating trial, Setx+/− and Setx−/− females produced significantly fewer pups than Setx+/+ females from 7 months of age onwards. These data show that SETX is critical for preventing POA in mice, likely by preserving DNA integrity in oocytes. Intriguingly, heterozygous Setx loss causes an equally severe impact on ovarian ageing as homozygous Setx loss. Because heterozygous SETX disruption is less likely to produce systemic effects, SETX compromise could underpin some cases of insidious POA.