bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of carrying capacity for bivalve mariculture in subtropical and tropical regions: the need for tailored management tools and guidelines
Authors: Anaïs Aubert , Adélaïde Aschenbroich , Jean‐Claude Gaertner , Oihana Latchere , Philippe Archambault , Nabila Gaertner‐Mazouni 
Published: January 2020

AbstractIn a context of increasing global food demand, the aquaculture sector, and more particularly bivalve mariculture, has expanded significantly. While the impact of bivalve mariculture was initially overlooked, it is now widely recognized that this industry can significantly impact the ecosystem and its services. Carrying capacity assessment tools have been developed accordingly and have proved to be a useful and efficient aid for mariculture management. However, carrying capacity assessment tools have been mostly designed and implemented in developed temperate countries, while bivalve mariculture is mainly expanding today in tropical and subtropical zones. To what extent the existing carrying capacity assessment tools are suited for use in tropical and subtropical regions has received little attention, and thus constitutes a major issue. The present review aims to fill this gap and highlights the key points to consider for the carrying capacity assessment of bivalve mariculture in tropical and subtropical regions. In line with the requirements for the sustainable development of human activities, and increasing recognition of the need for better integration of social aspects in the management processes, carrying capacity assessment should be undertaken in a more holistic way. Thus, the social, economic and environmental aspects are taken into account in our analysis. A step‐process plan for the sustainable management of bivalve mariculture in tropical and subtropical countries, through the assessment of carrying capacity, is proposed and discussed to offer guidance for managers.
Fluorescent fibre‐optic confocal characterization of in vivo epidermal changes in atopic eczema
Authors: Suihko Christian , Serup Jørgen 
Published: January 2020

AbstractBackground/aimsFibre‐optic confocal imaging (FOCI) allows non‐invasive visualization of live skin in vivo. A contrast agent, a fluorophore, is injected into the dermis. FOCI images are horizontal optical sections with cellular resolution. The aim was to study in vivo epidermal changes and the cellular structure of keratinocytes in moderate to severe atopic eczema (AE).MethodsEight patients with AE with active lesions on the forearms were studied and compared to a control group of six healthy individuals, and two cases of AE without activity. Fluorescein sodium was used as fluorophore. A hand‐held fibre‐optic laser scanner (Stratum®) was used. The study included morphometric analyses.ResultsThe confocal in vivo images identified characteristic features of epidermis and keratinocytes in active AE vs healthy skin controls. FOCI could non‐invasively image acanthosis, spongiosis, and parakeratosis in AE. Epidermal oedema and micro‐vesicles were visualized. Morphometry based on FOCI demonstrated 14% increased width of keratinocytes of atopic skin vs healthy controls. The epidermal structures and organization in distinctive cell layers were deviant as a result of the disease.ConclusionsFibre‐optic confocal imaging can visualize essential epidermal structures of atopic eczema directly in vivo, in real‐time, and with cellular resolution thus without disturbing the natural state of the skin. FOCI is primarily a research tool, but with a potential to become used in the clinic for non‐invasive microscopic diagnosis of AE and monitoring of effect of therapies.
Metamodeling Time-Temperature Creep Parameters
Authors: Haque Mohammad Shafinul , Stewart Calvin M. 
Published: January 2020

Abstract
There exist many time-temperature parameter (TTP) models for creep rupture prediction of components including the Larson–Miller (LM), Manson–Haferd (MH), Manson–Brown (MB), Orr–Sherby–Dorn (OSD), Manson–Succop (MS), Graham–Walles (GW), Chitty–Duval (CD), Goldhoff–Sherby (GS) models. It remains a challenge to determine which model is “best”, capable of accurate interpolation and physically realistic extrapolation of creep rupture data for a given material. In this study, metamodeling is applied to create a unified TTP metamodel that combines and regresses into twelve TTP models (eight existing and four newly derived). An analysis of the mathematical problems that exist in TTP models is provided. A matlab code is written that can: (1) calibrate the material constants of any of the twelve TTP models (using the metamodel); (2) determine the most suitable stress-parameter function; (3) and report the normalized mean square error (NMSE) of rupture predictions for a given material database. Using the metamodel, and code, a design engineer can make an intelligent selection of the “best” TTP model for creep resistant design. This process is demonstrated using four isotherms of alloy P91 creep rupture data. To assess the influence of material, further validation is performed on alloys Hastelloy X, 304SS, and 316SS. It is determined that the “best” model is dependent on material type and the quality and quantity of available data.
Editor's Welcome
Authors: Vivacqua Adriana S. , Erickson Ingrid , Christensen Lars Rune , Barkhuus Louise , Robert Lionel P. 
Published: January 2020

It is our pleasure to welcome you to this PACMHCI GROUP issue. For over 25 years, the GROUP research community has supported the development of robust scholarship at the intersection of Computer Supported Cooperative Work, Human Computer Interaction, Computer Supported Collaborative Learning and Socio-Technical Studies. This volume is the latest product of our efforts to validate and integrate the strong work happening within this broadly-conceived community.
We hope that the range of papers presented here reflects our intent to be international, interdisciplinary, and inclusive, both in our organization of the review process as well as within the set of accepted papers. This PACMHCI journal volume in the GROUP series features studies of collaboration in multiple settings, including social media, online communities and game development. It also showcases architectures and frameworks for collaboration, and sociotechnical studies in domains ranging from sports to fake news.
As Editors, we are particularly pleased to continue the legacy of presenting and disseminating the new and exciting work being developed in our community. We come together every two years to creatively display and build off of ideas from a wide range of disciplinary and topical areas including computer science, design, engineering, information science, management science, sociology, work and labor studies, and values-in-design, among others.
Fast Synthesis of Co3O4 by Microwave-Assisted Hydrothermal Treatment
Authors: Medina Midilane S. , Zenatti Alessandra , Escote Marcia T. 
Published: January 2020

This work describes a fast and simple procedure that combines the virtues of the microwave-assisted hydrothermal method with an oxidizing agent to produce Co3O4 nanocubes and nanoplates. We observed that particle morphology and size depend on the synthesis time and oxidizing agent (urea and hydrogen peroxide). The X-ray diffraction results showed that the samples are single phase, with crystallite sizes of approximately 30 nm. A similar crystalline domain is observed in the transmission electronic images. Magnetic measurements revealed the influence of the size and morphology of the particles on the magnetic curves. These measurements on the nanoplate samples revealed a paramagnetic behaviour at higher temperatures, and the presence of a cusp at that temperature was defined as TP. The TP decreases from 36 K to 21 K when the size of the plate particles decreases from ~70 nm to 10 nm. These samples also present weak ferromagnetism below TP, which is attributed to a superparamagnetic blockade state. The nanocube samples have a lower magnetic susceptibility magnitude and weak ferromagnetism behaviour at room temperature. Our results show that this synthesis produces Co3O4 nanoplates and nanocubes with interesting magnetic properties related to their shape and size.
EKONOMİK BÜYÜME VE ENERJİ TÜKETİMİNİN CO2 EMİSYONU ÜZERİNDEKİ ETKİLERİ: SEÇİLMİŞ MENA ÜLKELERİ İÇİN PANEL VERİ ANALİZİ
Authors: YÜCESAN Mesut , YAĞIŞ Onur , TORUN Mustafa 
Published: January 2020

Bu çalışmada, orta gelir düzeyine
sahip seçilmiş 8 MENA ülkesi; Cezayir, Mısır, İran, Irak, Ürdün, Lübnan, Tunus
ve Türkiye için ekonomik büyüme ve enerji tüketiminin co2 emisyonları
üzerindeki etkisi belirlenmeye çalışılmaktadır. 1988-2014 dönemi yıllık verileri
kullanılarak yatay kesit bağımlılığını göz önünde bulunduran panel veri analizi
yöntemiyle analiz edilmiştir. Serilerin durağanlığı; yatay kesit bağımlılığını
ve ortak faktörleri göz önünde bulunduran ikinci kuşak birim kök testlerinden
Hadri-Kurozumi (2012) testiyle incelenmiştir, eşbütünleşme ilişkisinin varlığı
Westerlung-Edgerton (2007) LM bootstrap testiyle, Eşbütünleşme analizinden
sonra uzun dönem katsayılarını tahmin etmek için AMG (Arttırılmış Ortalama Grup
tahmincisi, Augmented Mean Group estimator) yöntemi kullanılmıştır. Ayrıca nedensellik ilişkisi Dumitrescu-Hurlin (2012)
testiyle incelenmiştir. Çalışma sonucunda; ekonomik büyüme, enerji tüketimi
ile co2 emisyonları arasında
uzun dönemli bir
ilişki mevcuttur. Ülkelerin enerji tüketimlerindeki 1 birimlik yüzde artış co2
emisyonlarını 0.56 birim arttırmaktadır. Enerji tüketiminin etkilerinden sonra
ekonomik büyümenin etkilerine bakıldığında ekonomik büyümedeki 1 birimlik
artış co2 emisyonunu -0.90 birim
azaltmaktadır. Böylece enerji tüketiminin co2 emisyonunu artırdığına, ekonomik
büyümenin ise co2 emisyonlarını azalttıkları sonucuna ulaşılmıştır. İlaveten enerji tüketiminden
ekonomik büyümeye doğru ve ekonomik büyümeden enerji tüketimine doğru çift
yönlü nedensellik mevcuttur. Co2 emisyonundan ekonomik büyümeye doğru ve
ekonomik büyümeden co2 emisyonuna doğru çift yönlü bir nedensellik bulunmuştur.
İlaveten enerji tüketiminden co2 emisyonuna doğru tek yönlü bir nedensellik
ilişkisinin mevcut olduğu görülmektedir.
Clinician and patient barriers to the recognition of insomnia in family practice: a narrative summary of reported literature analysed using the theoretical domains framework
Authors: Ogeil Rowan P. , Chakraborty Samantha P. , Young Alan C. , Lubman Dan I. 
Published: January 2020

Abstract
Background
Insomnia is a common sleep complaint, with 10% of adults in the general population experiencing insomnia disorder, defined as lasting longer than three months in DSM-5. Up to 50% of patients attending family practice experience insomnia, however despite this, symptoms of insomnia are not often screened for, or discussed within this setting. We aimed to examine barriers to the assessment and diagnosis of insomnia in family practice from both the clinician and patient perspective.

Methods
The present article identified research that has examined barriers to assessing insomnia from the clinician’s and the client’s perspectives following MEDLINE and Google Scholar searches, and then classified these barriers using the theoretical domains framework.

Results
The most common barriers from the clinician’s perspective were related to Knowledge, Skills, and the Environmental Context. From the patient perspective, barriers identified included their Beliefs about the consequences of Insomnia, Social Influences, and Behavioural Regulation of Symptoms.

Conclusions
Utilising this theoretical framework, we discuss options for bridging the gap between the identification and subsequent management of insomnia within the family practice setting. To assist clinicians and those in community health care to overcome the Knowledge and Skills barriers identified, this article provides existing relevant clinical criteria that can be utilised to make a valid diagnosis of insomnia.
Resolving the formidable barrier of oxygen transferring rate (OTR) in ultrahigh-titer bioconversion/biocatalysis by a sealed-oxygen supply biotechnology (SOS)
Authors: Hua Xia , Zhou Xin , Du GenLai , Xu Yong 
Published: January 2020

Abstract
Background
The critical issue in the competitiveness between bioengineering and chemical engineering is the products titer and the volume productivity. The most direct and effective approach usually employs high-density biocatalyst, while the weakened mass transfer and evoked foam problem accompany ultrahigh-density biocatalyst loading and substrate/product titer. In high-density obligate aerobic bioconversion, oxygen as electron acceptor is a speed-limiting step in bioprocesses, but sufficient oxygen supply will lead to the foaming which results in a significant reduction in oxygen utilization and the use of additional defoamers. In this study, we designed a novel sealed-oxygen supply (SOS) biotechnology to resolve the formidable barrier of oxygen transferring rate (OTR), for bio-based fuels and chemical production process.

Results
Based on systemic analysis of whole-cell catalysis in Gluconobacter oxydans, a novel sealed-oxygen supply technology was smartly designed and experimentally performed for biocatalytic oxidation of alcohols, sugars and so on. By a simple operation skill of automatic online supply of oxygen in a sealed stirring tank bioreactor of SOS, OTR barrier and foaming problem was resolved with great ease. We finally obtained ultrahigh-titer products of xylonic acid (XA), 3-hydroxypropionic acid (3-HPA), and erythrulose at 588.4 g/L, 69.4 g/L, and 364.7 g/L, respectively. Moreover, the volume productivity of three chemical products was improved by 150–250% compared with normal biotechnology. This SOS technology provides a promising approach to promote bioengineering competitiveness and advantages over chemical engineering.

Conclusion
SOS technology was demonstrated as an economic and universally applicable approach to bio-based fuels and chemicals production by whole-cell catalysis. The novel technology greatly promotes the competitiveness of bioengineering for chemical engineering, and provides a promising platform for the green and environmental use of biofuels.
In vitro antifungal resistance profile of Candida strains isolated from Saudi women suffering from vulvovaginitis
Authors: Yassin Mohamed T. , Mostafa Ashraf A. , Al-Askar Abdulaziz A. , Bdeer Rashad 
Published: January 2020

Abstract
Background
Vulvovaginal candidiasis (VVC) represents a universal health hazard that contributes to significant morbidity in women. Resistance of Candida to antifungal therapy has been reported as a public health problem. So, the objective of our current study is to detect resistance profile of different candidal strains.

Methods
In this study, isolated Candida strains were identified by conventional methods, confirmed by internal transcribed spacer (ITS) sequencing, and phylogenetically analyzed with reference strains in GenBank. Also, sensitivity of different Candida strains to common antifungal agents was evaluated by disc diffusion method.

Results
Candida albicans was identified as the most frequent strain (63%) followed by non-albicans strains, such as C. glabrata (20%), C. tropicalis (13%), and C. krusei (4%). Sensitivity of Candida strains (C. albicans, C. tropicalis and C. glabrata) to commonly used antifungal agents was evaluated through the disc diffusion method. C. glabrata was the most resistant strain and considered to be a multidrug-resistant pathogen, while both, C. albicans and C. tropicalis showed high susceptibility to terbinafine. In contrast, C. albicans showed resistance to fluconazole, clotrimazole, and nystatin, while C. tropicalis, considered as the most sensitive strain, was susceptible to all the antifungal agents tested except nystatin. Terbinafine was the most effective antifungal agent against both C. tropicalis and C. albicans, and hence its minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) for C. albicans and C. tropicalis were evaluated. MICs of terbinafine against C. albicans and C. tropicalis were 5 μg/ml and 2.5 μg/ml, while their MFCs were 10 μg/ml and 5 μg/ml, respectively.

Conclusion
The emergence of resistant Candida strains necessitates conduction of the antifungal susceptibility test prior to deciding the medication regime.
Objective Response and Prolonged Disease Control of Advanced Adrenocortical Carcinoma with Cabozantinib
Authors: Kroiss Matthias , Megerle Felix , Kurlbaum Max , Zimmermann Sebastian , Wendler Julia , Jimenez Camilo , Lapa Constantin , Quinkler Marcus , Scherf-Clavel Oliver , Habra Mouhammed Amir , Fassnacht Martin 
Published: January 2020

Abstract

Background
Objective response of advanced adrenocortical carcinoma (ACC) to mitotane and cytotoxic chemotherapy regimen is only ~20% and early tumor progression is frequent. Previous clinical trials with oral multikinase inhibitors were negative, which has been attributed in part to inadvertent drug interaction with mitotane. Cabozantinib (CABO) is an inhibitor of c-MET, vascular endothelial growth factor receptor 2, AXL, and RET and approved for advanced kidney cancer, liver carcinoma after previous sorafenib, and medullary thyroid carcinoma.

Objective
To investigate the clinical efficacy and safety of CABO monotherapy in ACC patients.

Design
Retrospective cohort study.

Setting
Three referral centers for ACC (Germany, United States).

Results
Sixteen patients (13 female) with progressive ACC received CABO after previous mitotane in 15/16 and 3 (median, range 0-8) further systemic treatments. Prior CABO therapy, mitotane was discontinued in all patients. Mitotane plasma concentration was &lt;2 mg/L in 7/16 patients and discontinued &gt;12 months in 6 additional patients before CABO use. In 4/5 cases with available plasma samples, CABO concentration was in the expected steady-state range. Adverse events of grade 1/2 and 3 were observed in 13 and 3 patients, respectively, and consistent with the known safety profile of CABO. Best response was partial response in 3, stable disease in 5, and progressive disease in 8 patients. Median progression-free and overall survival was 16 and 58 weeks, respectively.

Conclusion
CABO monotherapy appears to be safe and effective as a monotherapy in advanced ACC after failing prior treatments. Therefore, prospective investigation of CABO in ACC patients is warranted.
Seasonality of Hypoosmolar Hyponatremia in Medical Inpatients – Data from a Nationwide Cohort Study
Authors: Kutz Alexander , Ebrahimi Fahim , Sailer Clara O , Wagner Ulrich , Schuetz Philipp , Mueller Beat , Christ-Crain Mirjam 
Published: January 2020

Abstract

Context
Hyponatremia is the most prevalent electrolyte disturbance in hospitalized patients. Previous studies have shown a seasonal variation of profound hyponatremia with higher prevalence during warmer months.

Objective
This study aimed at analyzing the seasonal prevalence and sex- and age-specific differences of hyponatremia in medical inpatients.

Design
Nationwide cohort study from January 2009 and December 2015 using prospective administrative data.

Setting
Medical inpatients.

Patients
Diagnosis of hypoosmolar hyponatremia.

Main outcome measures
The primary outcome was the monthly alteration in hyponatremia prevalence. Secondary outcomes were the association of outdoor temperature with hyponatremia prevalence and differences among sex and age groups.

Results
Of 2 426 722 medical inpatients, 84 210 were diagnosed with hypoosmolar hyponatremia, of whom 61% (n = 51 262) were female. The highest overall prevalence of hyponatremia was observed in July (4.5%, n = 8976); the lowest in December (2.7%, n = 6530). The overall prevalence of hyponatremia in women compared with men was higher by 58% (odds ratio [OR], 1.58; 95% confidence interval [CI], 1.56-1.60). The sex-specific difference was most pronounced in the warmest month of July (mean temperature 20.1°C (OR, 1.76; 95% CI, 1.68-1.84). We observed the strongest association between seasonality and hyponatremia in elderly (&gt;80 years) female inpatients admitted during the month of July (OR, 2.40; 95% CI, 2.20-2.62]).

Conclusion
The prevalence of diagnosed hypoosmolar hyponatremia in medical inpatients increases during summer months with higher outdoor temperature. Elderly female inpatients were most susceptible to the seasonal rise in hyponatremia prevalence.
Architectural Adventurism in Nineteenth-Century Colonial India: Begum Samru and Her Sardhana Church
Authors: Pandey Sharma Jyoti 
Published: January 2020

Abstract
This article explores the politically fluid and culturally hybrid environment of the Indian subcontinent during the late eighteenth and nineteenth centuries. Interaction between European mercenaries and their Indian patrons led to acculturation of both sides. This cultural affinity also extended into the realm of architecture and building patronage, resulting in a stylistic hybridity that drew upon both Indian and European traditions. This article examines the building projects of Begum Samru, bibi (consort) of a German mercenary and ruler of Sardhana near Delhi. The Begum, born a Muslim, converted to Christianity, but nonetheless still valued her roots, creating a syncretic identity that was reflected in her architectural patronage. The scope of her patronage went beyond domestic architecture to serve the cause of her adopted religion as well. While she donated generously to Catholic institutions, it was in the building of churches that the Begum resorted to what one may call architectural adventurism to mark her identity as a devout Catholic. Transcending the prevalent notions of space and aesthetics, the Begum's architectural trajectory was unconventional due to her gender, social status, faith, and patronage of churches. Commissioned in 1821, Sardhana's Catholic Church became a symbol of her architectural adventurism: it epitomized Begum Samru's feisty spirit and her quest to champion Catholicism in the subcontinent.
Atsaru al-‘Alāqah baīna Hifdzi al-Qur’ān wa Hifdzi al-Mufradāti Thullāb Madrasah al-Qur’ān al-Tsānawiyyah
Authors: Mazidatulfaizah Mazidatulfaizah 
Published: January 2020

ملخص
أن أهداف هذالبحث لمعرفة أثر العلاقة بين حفظ القرآن و حفظ المفردات. تستخدم الباحثة المدخل الكمي، و منهجه منهج السببية النقابي. و تختار الباحثة طلاب المدرسة الثانوية مدرسة القرآن تبوئيرنج جومبانج كمصادير البيانات لأن هذه المدرسة قد اشتهرت بانجاز طلابهم في حفظ القران. و أما اسلوب جمع البيانات المستخدم هو الإستبانة باختبار الصدق و الثبات. و تكون نتيجة هذا البحث كما يلي:١) ان تحليل البيانات الذي يُنال من نتيجة البحث يدل على ان مستوى تحفيظ القرآن فيها متوسط. ٢) ان تحليل البيانات الذي يُنال من نتيجة البحث يدل على ان قدرة حفظ المفردات فيها متوسط.٣) هناك أثر تحفيظ القرآن في تنمية قدرة حفظ المفردات. هذا الاثر متوسط بتوزيع %٢١ والباقي يأثر من متغير الآخر.
الكلمات الاساسية: حفظ القران, المفردات, اللغة العربية

Abstrak
Tujuan dari penelitian ini adalah untuk menyingkap kehebatan Al-Quran dengan mengetahui ada atau tidaknya pengaruh hafalan Al-Quran dalam meningkatkan kemampuan menghafal kosa kata Bahasa Arab. Peneliti menggunakan pendekatan kuantitatif, dan metodologinya adalah pendekatan kausalitas eksperimen. Peneliti memilih siswa sekolah Madrasah Aliyah Madrasatul Quran Tebuireng Jombang sebagai sumber data karena sekolah ini telah terkenal dengan prestasi siswa mereka dalam menghafal Alquran. Metode pengumpulan data yang digunakan adalah tes angket kejujuran dan reliabilitas. Hasil penelitian ini adalah sebagai berikut: 1) Analisis data yang didapat dari hasil penelitian menunjukkan bahwa tingkat hafalan Alquran dalam level menengah. 2) Analisis data yang diperoleh dari hasil penelitian menunjukkan bahwa kemampuan menghafal kosakata adalah dalam level menengah. 3) Terdapat pengaruh tahfizh Al-Quran terhadap kemampuan menghafal kosa kata bahasa Arab, terbukti dengan distribusi 21% dan sisanya dipengaruhi oleh variabel lain.
Kata kunci: Tahfizh al-quran, Kosa kata, Bahasa Arab