bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Wave Motion Intensities on Performance in a Simulated Search and Rescue Task and the Concurrent Demands of Maintaining Balance
Authors: Duncan Carolyn A. , Bishop Nicole , Komisar Vicki , MacKinnon Scott N. , Byrne Jeannette M. 
Published: September 2020

Objective The purpose of this study was to examine how intensity of wave motions affects the performance of a simulated maritime search and rescue (SAR) task. Background Maritime SAR is a critical maritime occupation; however, the effect of wave motion intensity on worker performance is unknown. Methods Twenty-four participants (12 male, 12 female) performed a simulated search and rescue task on a six-degree-of-freedom motion platform in two conditions that differed in motion intensity (low and high). Task performance, electromyography (EMG), and number of compensatory steps taken by the individual were examined. Results As magnitude of simulated motion increased, performance in the SAR task decreased, and was accompanied by increases in lower limb muscle activation and number of steps taken. Conclusions Performance of an SAR task and balance control may be impeded by high-magnitude vessel motions. Application This research has the potential to be used by maritime engineers, occupational health and safety professionals, and ergonomists to improve worker safety and performance for SAR operators.
Career Assistance From Psychology Programs and Career Services: Who Is Preparing Psychology Students?
Authors: Conroy Jessica C. , Stamm Karen E. , Pfund Rory A. , Christidis Peggy , Hailstorks Robin , Norcross John C. 
Published: September 2020

Background: Despite the popularity of the undergraduate psychology major, little is known about career support and preparation available to psychology students. Objective: This study examined the prevalence, types, and methods of career assistance available to undergraduate psychology students both through their psychology programs and through their institutional career services. Method: A total of 240 programs from a stratified random sample of institutions offering undergraduate psychology programs responded to an online survey, yielding a response rate of 42.5%. Results: Undergraduate psychology programs most often provided assistance in applying to graduate school, while career services provided a wider range of resources. Baccalaureate institutions offer career assistance, via the psychology program or the institutional career center, more frequently than associate institutions. Most common forms of assistance consisted of instruction on how to apply for a job, how to find information about career possibilities in psychology subfields, resumé or curriculum vitae preparation, and individual advising. Conclusion: Although career assistance was widely available, there are several ways in which the type and scope of assistance can be improved upon to better support students and increase access. Teaching implications: Undergraduate psychology students could benefit from more career assistance content throughout psychology curricula.
Communicative Participation and Quality of Life in Pretreatment Oral and Oropharyngeal Head and Neck Cancer
Authors: Sauder Cara , Kapsner‐Smith Mara , Baylor Carolyn , Yorkston Kathryn , Futran Neal , Eadie Tanya 
Published: September 2020

ObjectiveTo determine how communicative participation is affected in patients with oral and oropharyngeal head and neck cancers (HNCs) pretreatment and whether communication function predicts HNC‐specific quality of life (QOL) before treatment, beyond known demographic, medical, psychosocial, and swallowing predictors.Study DesignCross‐sectional study.SettingTertiary care academic medical center.MethodsEighty‐seven patients with primary oral (40.2%) or oropharyngeal (59.8%) HNC were recruited prior to treatment. T stage, tumor site, and p16 status were extracted from medical records. Demographic and patient‐reported measures were obtained. Communicative participation was measured using the Communicative Participation Item Bank (CPIB) General short form. A hierarchical regression analysis included demographic, medical, psychosocial, and functional measures of swallowing and communication as predictors; the University of Washington Quality of Life (UW‐QOL v4) composite score was the predicted variable.ResultsMedian (SD) baseline CPIB scores were 71.0 (11.83); patients with oral cancers reported worse scores. A final sequential hierarchical regression model that included all variables explained 71% of variance in QOL scores. Tumor site, T stage, and p16 status accounted for 28% of variance (P <. 001). Perceived depression predicted an additional 28% of the variance (P <. 001). Swallowing and communicative participation together predicted an additional 12% of variance (P =. 005). Tumor site, perceived depression, swallowing, and communication measures were unique predictors in the final model. Finally, communicative participation uniquely predicted QOL, above and beyond other predictors.ConclusionPretreatment communication predicted QOL and was negatively affected in some oral and oropharyngeal patients with HNC.
The Gender Gap: Looking at the Entire Distribution
Authors: Farja Yanay , Tillman Avi , Zax Ori 
Published: September 2020

We propose a new method of estimating wage differences among individuals from different populations, which is based on looking at the distribution of fixed effects from a wage regression. We use this method to compare males’ and females’ wage distribution at different levels of education and at different ages. In most cases, unobserved, time-constant factors increase the wage of males, compared to that of females, by a constant share. But this is not true when looking at the tails of the distribution. We also discuss the advantages of our method. JEL: J71, J31
A therapeutic concept to resolve a possible coronary desaturation under Ecpella support and maximize the potential for myocardial recovery: combination of veno-arteriovenous extracorporeal membrane oxygenation and Impella (VAVEcpella)
Authors: Ushijima Tomoki , Sonoda Hiromichi , Tanoue Yoshihisa , Shiose Akira 
Published: September 2020

Introduction: Ecpella, a combination of veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) and Impella, may result in the differential hypoxia in patients with cardiogenic shock and severe lung dysfunction. Here, we report a solution of this Ecpella-induced unfavorable phenomenon. Case report: A 70-year-old man developed cardiogenic shock from fulminant myocarditis. As we established Ecpella but immediately significant differential hypoxia became apparent, the ECMO configuration was switched from V-A to veno-arteriovenous (V-AV): a combination of V-AV ECMO and Impella, newly termed VAVEcpella, was instituted. The differential hypoxia resolved, and he was successfully weaned from mechanical circulatory support. Discussion and conclusion: VAVEcpella is an effective configuration to resolve Ecpella-induced differential hypoxia and may contribute to restoration of normal cardiac function.
A randomized clinical trial of the effects of saphenous and perforating veins radiofrequency ablation on venous ulcer healing (VUERT trial)
Authors: Puggina Juliana , Sincos Igor Rafael , Campos Walter , Porta Rina Maria P , dos Santos Jorgete Barreto , De Luccia Nelson , Puech-Leão Pedro , Collares Felipe Birchal , da Silva Erasmo Simão 
Published: September 2020

Objectives To investigate whether radiofrequency endovenous ablation (RFA) of saphenous and perforating veins increases venous leg ulcer (VLU) healing rates and prevents ulcer recurrence. Method This prospective, open-label, randomized, controlled, single-center trial recruited 56 patients with VLU divided into: compression alone (CR, N = 29) and RFA plus compression (RF, N = 27). Primary endpoints were ulcer recurrence rate at 12 months; and ulcer healing rates at 6, 12, and 24 weeks. Secondary endpoints were ulcer healing velocity; and Venous Clinical Severity Score (VCSS). Results Recurrence was lower in the RF group (p < .001), as well as mean VCSS after treatment (p = .001). There were no significant between-group differences in healing rates. Healing velocity was faster in the RF group (p = 0.049). In the RF group, 2 participants had type 1 endovenous heat-induced thrombosis (EHIT). Conclusions RFA plus compression is an excellent treatment for VLU because of its safety, effectiveness, and impact on ulcer recurrence reduction and clinical outcome. Registration: Clinicaltrials.gov, NCT03293836, clinicaltrials.gov.
Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey
Authors: Datta Rupak , Topal Jeffrey , McManus Dayna , Sanft Tara , Dembry Louise Marie , Morrison Laura J , Quagliarello Vincent , Juthani-Mehta Manisha 
Published: September 2020

Background: Antimicrobial use during end-of-life care of older adults with advanced cancer is prevalent. Factors influencing the decision to prescribe antimicrobials during end-of-life care are not well defined. Aim: To evaluate factors influencing medicine subspecialists to prescribe intravenous and oral antimicrobials during end-of-life care of older adults with advanced cancer to guide an educational intervention. Design: 18-item single-center cross-sectional survey. Setting/participants: Inpatient medicine subspecialists in 2018. Results: Of 186 subspecialists surveyed, 67 (36%) responded. Most considered withholding antimicrobials at the time of clinical deterioration during hospitalization ( n = 54/67, 81%), viewed the initiation of additional intravenous antimicrobials as escalation of care ( n = 44/67, 66%), and believed decision-making should involve patients or surrogates and providers ( n = 64/67, 96%). Fifty-one percent ( n = 30/59) of respondents who conducted advance care planning did not discuss antimicrobials. Barriers to discussing end-of-life antimicrobials included the potential to overwhelm patients or families, challenges of withdrawing antimicrobials, and insufficient training. Conclusions: Although the initiation of additional intravenous antimicrobials was viewed as escalation of care, antimicrobials were not routinely discussed during advance care planning. Educational interventions that promote recognition of antimicrobial-associated adverse events, incorporate antimicrobial use into advance care plans, and offer communication simulation training around the role of antimicrobials during end-of-life care are warranted.
Fast Starters and Slow Starters After Hip Arthroscopy for Femoroacetabular Impingement: Correlation of Early Postoperative Pain and 2-Year Outcomes
Authors: Nguyen Thu Quynh , Friedman James M. , Flores Sergio E. , Zhang Alan L. 
Published: September 2020

Background: Patients experience varying degrees of pain and symptoms during the early recovery period after hip arthroscopy for femoroacetabular impingement (FAI). Some “fast starters” report minimal discomfort and are eager to advance activities, while “slow starters” describe severe pain and limitations. The relationship between these early postoperative symptoms and 2-year outcomes after hip arthroscopy is unknown. Purpose: To analyze the relationship between early postoperative pain and 2-year patient-reported outcomes (PROs) after hip arthroscopy for FAI. Study Design: Cohort study; Level of evidence, 2. Methods: Patients without arthritis or dysplasia who were undergoing primary hip arthroscopy for FAI were prospectively enrolled and completed validated PROs. Scores for visual analog scale (VAS) for pain were collected preoperatively and at 1 week, 6 weeks, and 2 years postoperatively. Scores for the modified Harris Hip Score (mHHS), Hip disability and Osteoarthritis Outcome Score (HOOS), and 12-Item Short Form Health Survey (SF-12) were collected preoperatively and 2 years postoperatively. Paired t tests were used to evaluate PRO score changes, and correlation analyses were used to assess relationships between early postoperative pain and 2-year postoperative outcomes. Results: A total of 166 patients were included (55% female; mean ± SD age, 35.29 ± 9.6 years; mean body mass index, 25.07 ± 3.98 kg/m2). Patients demonstrated significant improvements in PRO scores (VAS, SF-12 Physical Component Score, mHHS, and all HOOS subscales) at 2 years after hip arthroscopy for FAI ( P < .001). There was a significant correlation between lower 1-week VAS pain level (fast starters) and lower 2-year VAS pain level ( R = 0.31; P < .001) as well as higher 2-year PRO scores (SF-12 Physical Component Score, mHHS, and all HOOS subscales: R = −0.21 to −0.3; P < .001). There was no correlation between 1-week VAS pain and 2-year SF-12 Mental Component Score ( P = .17). Preoperative VAS pain levels showed positive correlations with 1-week postoperative pain scores ( R = 0.39; P < .001) and negative correlations with 2-year patient outcomes ( R = −0.15 to −0.33, P < .01). There was no correlation between 6-week postoperative pain scores and 2-year PRO scores. Conclusion: Fast starters after hip arthroscopy for FAI experience sustained improvements in outcomes at 2 years after surgery. Patient pain levels before surgery may delineate potential fast starters and slow starters.
Psychiatric Disability in Ontario
Authors: Goering Paula , Lin Elizabeth , Campbell Dugal , Boyle Michael H , Offord David R 
Published: September 2020

Objective To describe the disability associated with psychiatric disorder in a community sample in order to refine estimates of service need and identify subgroups with greater priority for intervention. Method Disability is conceptualized broadly as performance difficulties, troubled relationships, and dissatisfaction in various life domains. Data from the Mental Health Supplement are used to compare disability between those with and without disorder and among various subtypes of disorder. Results Although the majority of those with disorder do not report disability, their difficulties with functioning are far greater than for the rest of the population. Those with comorbid or affective disorders typically have more disability than those with anxiety or substance abuse disorders. Conclusions Society needs to recognize the high human and economic costs associated with the prevalence of psychiatric disorder. Assessments of service need and decisions about priorities should take both disorder and disability into consideration.
Boricua Founder Variant in FRRS1L Causes Epileptic Encephalopathy With Hyperkinetic Movements
Authors: Abdelmoumen Imane , Jimenez Sandra , Valencia Ignacio , Melvin Joseph , Legido Agustin , Diaz-Diaz Mayela M. , Griffith Christopher , Massingham Lauren J. , Yelton Melissa , Rodríguez-Hernández Janice , Schnur Rhonda E. , Walsh Laurence E. , Cristancho Ana G. , Bergqvist Christina A. , McWalter Kirsty , Mathieson Iain , Belbin Gillian M. , Kenny Eimear E. , Ortiz-Gonzalez Xilma R. , Schneider Michael C. 
Published: September 2020

Objective: To describe a founder mutation effect and the clinical phenotype of homozygous FRRS1L c.737_739delGAG (p.Gly246del) variant in 15 children of Puerto Rican (Boricua) ancestry presenting with early infantile epileptic encephalopathy (EIEE-37) with prominent movement disorder. Background: EIEE-37 is caused by biallelic loss of function variants in the FRRS1L gene, which is critical for AMPA-receptor function, resulting in intractable epilepsy and dyskinesia. Methods: A retrospective, multicenter chart review of patients sharing the same homozygous FRRS1L (p.Gly246del) pathogenic variant identified by clinical genetic testing. Clinical information was collected regarding neurodevelopmental outcomes, neuroimaging, electrographic features and clinical response to antiseizure medications. Results: Fifteen patients from 12 different families of Puerto Rican ancestry were homozygous for the FRRS1L (p.Gly246del) pathogenic variant, with ages ranging from 1 to 25 years. The onset of seizures was from 6 to 24 months. All had hypotonia, severe global developmental delay, and most had hyperkinetic involuntary movements. Developmental regression during the first year of life was common (86%). Electroencephalogram showed hypsarrhythmia in 66% (10/15), with many older children evolving into Lennox-Gastaut syndrome. Six patients demonstrated progressive volume loss and/or cerebellar atrophy on brain magnetic resonance imaging (MRI). Conclusions: We describe the largest cohort to date of patients with epileptic encephalopathy. We estimate that 0.76% of unaffected individuals of Puerto Rican ancestry carry this pathogenic variant due to a founder effect. Children homozygous for the FRRS1L (p.Gly246del) Boricua variant exhibit a very homogenous phenotype of early developmental regression and epilepsy, starting with infantile spasms and evolving into Lennox-Gastaut syndrome with hyperkinetic movement disorder.
Mental Health of Adolescents With Epilepsy in Enugu, Nigeria: A Cross-Sectional Study
Authors: Nnajekwu Chukwubike Onyebuchi , Nnajekwu Uchenna Chiagoziem , Ikefuna Nnaemeka Anthony , Ojinnaka Chinyelu Ngozi 
Published: September 2020

Adolescence is an important period, marked by significant changes in biological and psychosocial domains. Epilepsy is a chronic neurologic disorder associated with social stigma and prejudice. The etiology of depression in epilepsy appears to be a complex interplay between psychosocial and neurobiologic factors. This period may be too taxing for the adolescent with epilepsy to steer, as epilepsy can affect the development of independence by its social, educational, and mental health effects. The study aimed to compare the burden of depression in adolescents with epilepsy with the general population. One hundred forty-five adolescents with epilepsy and their classmates matched for age and gender were studied over a 9-month period. Zung Self-rating Depression Scale was used to determine the burden of depression in the study population. Among the subjects, 70 (48.3%) had scores in the depressive range to varying degrees compared to 38 (26.2%) controls. The difference in scores was significant (OR=2.628, P < .001). Among the population with positive scores, mild depression category was the commonest for both groups (40% and 22.8%, respectively). There was a statistically significant relationship between gender, seizure type, and depression, whereas there was no significant relationship between age, social class, number of antiepileptic drugs, seizure frequency in the last 12 months, and depression. Adolescents with epilepsy had higher rates of depression than the general population. Hence, there might be need for routine screening of adolescents with epilepsy for early detection and management of depression to improve their overall well-being and quality of life.
Ethical issues related to eHealth: An integrative review
Authors: Jokinen Anu , Stolt Minna , Suhonen Riitta 
Published: September 2020

Background: Identifying and safeguarding ethics in eHealth services from the service users’ perspective in social care and healthcare is important. The use of eHealth services should not prejudice the quality of services or the social interaction required in care. There is a lack of studies about the ethics of eHealth services from the service users’ perspective. Aim: The aim of this study is to identify and analyse ethical issues related to eHealth in social care and healthcare from the service users’ perspective. Research design: An integrative literature review. Ethical considerations: The review followed good scientific conduct. Research context and data sources: A systematic literature search was performed using CINAHL, Scopus, PubMed/MEDLINE, Web of Science, Cochrane Library and Academic Search Premier to find relevant empirical studies published in English from their earliest up to 30 November 2018. In addition, reference lists from the identified research papers were searched. A quality appraisal of each paper included in the review was conducted before thematic analysis. Results: In total, 26 studies were included in the review, and from these four ethical themes were identified: (1) privacy in eHealth, (2) beneficence and nonmaleficence in eHealth, (3) justice in eHealth and (4) trust in eHealth. The ethical issues within these themes were related to information sharing; ownership; access to information and data protection; informed consent; defence of rights; and equity, equality and proportionality of response. Conclusion: eHealth inequality occurs in social care and healthcare. eHealth service designers and social care and healthcare professionals need to act to maintain and improve user access and data accuracy and provide different levels of security in eHealth services, relative to the information stored. There is a need for further research about ethical issues of eHealth from the user’s perspective, including the customer-oriented availability and usability of eHealth services which avoid discrimination.
An fNIRS examination of executive function in bilingual young children
Authors: Xie Sha , Wu Dandan , Yang Jinfeng , Luo Jiutong , Chang Chunqi , Li Hui 
Published: September 2020

Aims: The present study aims to examine: (1) the relationship between young children’s bilingualism and their performance in the Dimensional Card Change Sort (DCCS) task; and (2) whether prefrontal activation was associated with children’s bilingualism and executive function. Methodology: Children performed three sessions of the DCCS and their brain activity during the task was measured using functional nearinfrared spectroscopy (fNIRS). Data and analysis: A sample of bilingual children ( N = 49) was recruited from a preschool with an English immersion program. We examined whether children’s performance in the DCCS was related to their bilingualism and whether the changes in oxygenated hemoglobin in the prefrontal regions were related to their bilingualism and performance in the DCCS. Findings/conclusions: Results showed that children’s English ability was significantly correlated with their behavioral performance in DCCS, and predicted children’s group membership (pass or perseverate). Furthermore, children in the pass group significantly activated the prefrontal cortex than those in the perseverate group, and activation in the prefrontal region was significantly correlated with children’s English ability. Originality: The current study first examined the effect of children’s bilingualism on their executive function and prefrontal activation.
Trends in older adults’ alcohol use in Norway 1985–2019
Authors: Bye Elin K , Moan Inger Synnøve 
Published: September 2020

Aims: To examine the prevalence of and trends in older adults’ (60–79 years) alcohol use in Norway between 1985 and 2019. Methods: Data stem from two repeated cross-sectional surveys in the Norwegian population: Statistics Norway’s Health and Living Conditions Surveys from 1985 ( N = 7799), 1995 ( N = 3518) and 2005 ( N = 6487), and the Norwegian Institute of Public Health’s (NIPH) annual surveys on alcohol, tobacco and drug use from 2012/2013 ( N = 4047), 2014/2015 ( N = 4378), 2016/2017 ( N = 4264) and 2018/2019 ( N = 4330). The following measures were used to examine trends in alcohol use among women and men aged 60 and older: drinking status, drinking frequency, number of drinks per occasion, and frequency of heavy episodic drinking (HED). Results: Between 1985 and 2019, there has been a substantial increase in the proportions of older adults in Norway who drink alcohol and who drink relatively often. The increase was particularly marked between 1985 and 2012/2013, and for elderly women. However, the majority of older adults drink small amounts of alcohol on typical drinking occasions, illustrating that the increased frequency of drinking is not accompanied by a corresponding increase in risky drinking. Conclusions: There has been a marked increase in alcohol use among older adults the past 30 years, particularly among older women, suggesting that the age and gender gap traditionally found in alcohol use in Norway is diminishing. Due to the lower alcohol tolerance among elderly, monitoring the changing trends in alcohol use in this group, as well as the possible consequences of these changes, is important.