bluuebunny/crossref_metadata_2025_split huggingface dataset:
The substance use profiles of adults who sought mental health and addiction services through a centralized intake process in Nova Scotia (2020–2021)
Authors: Soboka Matiwos , Tibbo Philip G. , Stewart Sherry H. , Simon Patryk , Wang JianLi 
Published: December 2024

BackgroundDespite the increasing substance use in Canada, our understanding of how substance use varies based on the intersections of gender, ethnicity/race, and income sources among preclinical populations remains limited. Thus, this study aimed to investigate, among clients of mental health and addiction (MHA) intake in Nova Scotia: 1) the prevalence of substance use by gender, ethnicity, and income source; 2) the routes of substance administration; 3) factors associated with substance use. Understanding how gender, ethnicity, and income sources intersect to influence substance use patterns is essential for designing prevention and treatment strategies tailored to an individual’s unique needs. Additionally, exploring the various routes of substance administration can provide insight into potential health risks, helping to inform harm reduction strategies.MethodsThis cross-sectional study included 22,500 adults who contacted MHA central intake in Nova Scotia in 2020 and 2021. Clients were assessed for substance use, substance use frequency, route of substance administration, and mental and physical health problems. The prevalence of substance use was examined as a function of gender, ethnicity, and income source. Multinomial logistic regression was used to investigate factors associated with substance use.ResultsAmong the included MHA Intake clients, 36.1% reported daily substance use. The highest prevalence of daily substance use was identified among homeless (69.7%) and non-White men on social assistance/disability (60.9%). Also, non-White individuals on social assistance/disability were more likely to engage in frequent (aOR = 2.66, 95% =1.64, 4.30) and daily (aOR = 2.82, 95% CI: 2.08, 3.82) substance use compared to White individuals. Being young (aged 19-29), lack of access to private insurance, current/past mental illness, moderate/high suicide risk, and presence of two or more psychosocial stressors, were associated with occasional, frequent, and daily substance use alike.ConclusionsThe high prevalence of daily substance use among MHA Intake service users in Nova Scotia highlights the need for prevention and treatment strategies to address individual and structural level factors contributing to daily substance use.
Unemployment and mental health: a global study of unemployment’s influence on diverse mental disorders
Authors: Yang Yang , Niu Lisi , Amin Saqib , Yasin Iftikhar 
Published: December 2024

IntroductionGlobally, one in five individuals faces unemployment, which substantially increases their risk of developing mental disorders. Understanding the relationship between unemployment and specific mental health outcomes is crucial for formulating effective policy interventions.MethodsThis study examines the relationship between unemployment and mental disorders across 201 countries from 1970 to 2020. Using a fixed-effects model, we analyze the impact of unemployment on various mental health outcomes, including anxiety, depression, bipolar disorder, drug use, and eating disorders, with a focus on demographic variations.ResultsThe analysis reveals a significant positive association between unemployment and mental disorders, particularly anxiety, depression, and bipolar disorder. Moreover, distinct patterns emerge, linking unemployment to higher rates of drug use and eating disorders in specific demographics.DiscussionThese findings underscore the critical interplay between socio-economic factors and mental health, highlighting the need for proactive strategies to address the dual burden of unemployment and mental health disorders. Targeted interventions, such as employment support programs and accessible mental health services, are essential to improve global mental health outcomes. These initiatives can also alleviate the economic burden of unemployment by boosting workforce participation and productivity. Long-term economic gains may offset the increased healthcare expenditures associated with mental health support.
The effect of activities of daily living on anxiety in older adult people: the mediating role of social participation
Authors: Zheng Juan , Xu Jianqiang , Liu Daqi 
Published: December 2024

ObjectiveAnxiety is a serious psychiatric illness in older adult people. Activities of daily living and social participation are important factors influencing anxiety in older adult people. Using social participation as a mediating variable, this study explored the influence of activities of daily living on anxiety in older adult people to provide scientific evidence for improving the psychological health of older adult people.MethodsA multistage stratified random sampling method was used in this study to recruit older adult people. T tests and variance analysis were used for single factor analysis, and a multiple linear regression model was used for multifactor analysis. Pearson correlation analysis was used to study the correlation between activities of daily living and social participation and anxiety. The Process program was used to perform the bootstrap test.ResultsThe mean anxiety score of the interviewed older adult individuals was 3.028 ± 4.606 points, and 28.66% of the older adult individuals had anxiety. There was a statistically significant difference in the anxiety scores of older adult people across sex, age, marital status, education level, and health insurance status (p &lt; 0.05). After controlling for other variables, each one-point increase in the activities of daily living score significantly increased the anxiety score by 0.122 points (𝛽=0.122, p &lt; 0.001), and each one-point increase in the social participation score significantly decreased the anxiety score by 0.058 points (𝛽= − 0.058, p &lt; 0.001). According to the results of the mediating effect analysis, there was a significant positive relationship between activities of daily living and anxiety, and the total effect was established (𝛽=0.1719, p &lt; 0.001). After controlling for social participation, there was a significant direct effect of activities of daily living on anxiety in older adult people (𝛽=0.1255, p &lt; 0.001). A partial mediating effect of social participation on the relationship between activities of daily living and anxiety in older adult people was found. The indirect effect of social participation was 26.99%.ConclusionActivities of daily living and social participation are important factors affecting anxiety in older adult people. Health education should be increased to enhance the physical activity of older adult people to improve their activities of daily living, create a good atmosphere for their social participation, improve their motivation for and continuity of social participation.
Disparities in PrEP use and unmet need across PEPFAR-supported programs: doubling down on prevention to put people first and end AIDS as a public health threat by 2030
Authors: Mukherjee Trena I. , Yep Mitchell , Koluch Megan , Abayneh Sisay Alemayehu , Eyassu Gizachew , Manfredini Elizabeth , Herbst Sara 
Published: December 2024

BackgroundIn 2023, an estimated 1.3 million people newly acquired HIV. In the same year, 3.5 million individuals received pre-exposure prophylaxis (PrEP), falling short of the UNAIDS target of 21.2 million by 2025. With over 90% of global PrEP programming supported by PEPFAR, a better understanding of disparities in PrEP provision is needed to inform PEPFAR's approach to reach and deliver prevention services and achieve UNAIDS 95-95-95 goals in all populations by 2025. The objective of this paper is to assess unmet PrEP need in PEPFAR-supported countries.MethodsWe analyzed FY2023 Monitoring, Evaluation, and Reporting (MER) results from 48 PEPFAR-supported countries to calculate PrEP-to-need ratios (PnR) by geography and population. PnR offers an ecological measure to identify disparities and missed opportunities for PrEP programming. PnR was calculated as the ratio of PrEP users to the number of positive HIV tests. PrEP users are defined through new initiations (PrEP_NEW) and re-initiations or continuation (PrEP_CT). HTS_TST_POS measures the number of positive HIV tests and was used as a proxy for new diagnoses. PnR was also calculated using Naomi-estimated 2023 HIV incidence, where available. A higher PnR indicates more PrEP users relative to PrEP need in a population.ResultsIn FY23, 1,760,888 people initiated PrEP, and 1,736,144 people tested positive for HIV. PnR ranged from 0.12 (India) to 6.46 (Brazil), and 19 (40%) countries had fewer PrEP users than positive HIV tests (PnR &lt;1.0). By population, people 15–24 years old, people who inject drugs, and transgender populations had the highest median PnR. When examining estimated HIV incidence, Mozambique and South Africa reported lower than average PnR and higher than average HIV incidence.ConclusionPrEP use relative to population need varied greatly by country and subpopulation across PEPFAR programs, suggesting a need for greater advocacy, inclusivity, accessibility, and integrated prevention programming. PnR may be a useful indicator of population PrEP coverage and unmet need, and can inform effective, data-driven, and person-centered PEPFAR prevention programming and policies. Tailoring PrEP scale-up strategies by age, sex, key population, and geography is crucial to achieving UNAIDS targets and ending the AIDS epidemic as a public health threat for all by 2030.
Numerical Study and Optimization-Based Sensitivity Analysis of a Vertical-Axis Wind Turbine
Authors: El Maani Rabii , Radi Bouchaib , El Hami Abdelkhalak 
Published: December 2024

This study aims to introduce a new optimization method for designing a vertical-axis wind turbine (VAWT) that dynamically morphs its blades as a function of the tip-speed ratio (TSR) and azimuthal angle. For this purpose, the Darrieus turbine is the subject of a dynamic study under transient aerodynamic loads. By resolving the two-dimensional unsteady incompressible Navier–Stokes equation, the aerodynamic torque is obtained with the k-ϵ realizable turbulence model. A comparison between rotor operation at optimal and lower Cp values is possible according to the investigation of flow-field characteristics for a variety of tip-speed ratio values, with experimental results so that a better understanding of the vertical-axis wind turbine’s basic physics is obtained. Then, a multi-objective optimization technique is coupled with ANSYS Workbench to increase the energy generation of VAWT blades by reducing the drag coefficient and maximizing the power coefficient. The input variables were evaluated through a sensitivity analysis, and the most important one was chosen. The analysis results of the best compromise showed that the design methodology’s output is feasible for manufacturing.
O impacto da pandemia de COVID-19 no risco de fragilidade em idosos atendidos no ambulatório de geriatria do Hospital Universitário João de Barros Barreto (HUJBB)
Authors: Nascimento Natália da Silva , Monteverde Beatriz Tavares 
Published: December 2024

A síndrome de fragilidade é uma condição geriátrica associada à sarcopenia, desregulação neuroendócrina e imunológica. Durante a pandemia de COVID-19, medidas de isolamento foram necessárias para proteger pessoas com mais de 60 anos, grupo de maior risco de complicações graves. Este estudo transversal quantitativo avaliou 100 idosos atendidos no ambulatório de geriatria do Hospital Universitário João de Barros Barreto (HUJBB) em 2022. Os participantes, com 60 anos ou mais, assinaram o Termo de Consentimento Livre Esclarecido (TCLE) e foram avaliados pelo Índice de Vulnerabilidade Clínico-Funcional do Idoso (IVCF-20). Observou-se que 57% tinham entre 60-74 anos, sendo 75% do sexo feminino. Quanto ao risco de fragilidade, 26% apresentaram baixo risco, 36% moderado e 38% alto risco, com associação significativa entre fragilidade e faixa etária (p=0.0286), perda de apetite (p=0.072) e sensação de fraqueza (p=0.0262) durante a pandemia. As comorbidades mais comuns foram hipertensão arterial (69%), diabetes mellitus (38%) e doenças osteoarticulares (34%), embora sem associação significativa com a fragilidade (p>0.05). Os resultados evidenciam os impactos negativos da pandemia, que aumentaram a vulnerabilidade dos idosos, destacando a necessidade de classificação de risco para melhores cuidados e intervenções no envelhecimento.
Análise de cariótipo e PCR X-frágil de indivíduos provenientes de Maringá, Paraná e região
Authors: Gomes Lucas Pozza , Molinari Isabella Fantini , Moraes Cesar Augusto Machado de , Vidotti Rodrigo Ignatowicz , Lima Vitória Santos , Naime Vitória Maria do Prado , Araujo Mariane Castardo , Silva Maria Fernanda Piffer Tomasi Baldez da 
Published: December 2024

Trata-se de um estudo transversal, de caráter clínico e experimental, cujo objetivo consistiu em analisar amostras de sangue periférico e/ou swab oral de pacientes com suspeita de síndrome genética não diagnosticados ou subdiagnosticados provenientes de Maringá (Paraná) e região, por meio do exame de Cariótipo por Bandeamento G e Reação em Cadeia da Polimerase (PCR) para cromossomo X-Frágil. As amostras de sangue periférico foram processadas realizando o cultivo de linfócitos, seguido da confecção de lâminas para cariótipo que passaram por visualização e avaliação em microscopia óptica. Foram analisadas cerca de 20 metáfases por paciente. As amostras de swab oral, por sua vez, foram pesquisadas para diagnóstico molecular da Síndrome do Cromossomo X-Frágil (SXF) através de PCR do gene FMR1. Foram realizados 35 exames de cariótipo e 6 exames de PCR, a partir dos quais foram obtidos 26 cariótipos nos padrões da normalidade e 9 contendo alterações, incluindo trissomia do cromossomo 21 e mosaicismo dos cromossomos 21 e 22. Dos 6 exames de PCR, foram obtidos 5 resultados nos padrões da normalidade e 1 positivo para cromossomo X-Frágil.
ANALISIS LAPORAN ARUS KAS DALAM MENILAI KINERJA PERUSAHAAN AIR MINUM KEMASAN TAHUN 2018-2022
Authors: Nurlaila Nurlaila , Nurmalina Radna , Sur Widiya Astuti Alam 
Published: December 2024

Penyusunan laporan arus kas perusahaan adalah salah satu indikator yang dapat digunakan untuk menilai kinerja perusahaan. Saat terjadi pandemi Covid–19, banyak perusahaan yang terdampak termasuk pada perusahaan air minum PT Sariguna Primatirta. Kinerja perusahaan menjadi naik dan turun untuk terus bisa survive selama dan dan setelah pandemi. Penelitian ini bertujuan untuk menganalisis dampak pandemi Covid–19 terhadap kinerja perusahaan PT Sariguna Primatirta. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif dengan tujuan menggambarkan kinerja laporan keuangan PT Sariguna Primatirta. Data dikumpulkan melalui melalui pengumpulan data sekunder yang berupa informasi laporan keuangan perusahaan selama lima periode mulai dari tahun 2018 hingga tahun 2022. Teknik pengumpulan data menggunakan teknik dokumentasi pada laporan neraca serta laporan laba rugi perusahaan. Metode analisis menggunakan data deskriptif kualitatif dengan menggunakan rasio keuangan kemudian disampaikan kembali dengan lebih informatif dan mudah dipahami. Berdasarkan hasil analisis yang telah dilakukan, laporan keuangan perusahaan menunjukkan kinerja keuangan PT Sariguna Primatirta mengalami kinerja yang kurang stabil. Melalui hasil arus kas operasi terhadap hutang lancar yang tidak menunjukkan kenaikan signifikan dari tahun 2018 sampai tahun 2022. Rasio cakupan arus kas terhadap bunga mengalami kinerja yang baik dilihat dari jumlah rasionya yang lebih dari 1. Rasio pengeluaran modal dan rasio total hutang yang mengalami kinerja kurang baik karena jumlah rasionya kurang dari 1. Rasio cakupan kas terhadap hutang lancar mengalami kenaikan yang signifikan berdasarkan nilai rasio cakupan kas yang meningkat dari tahun 2018 sampai tahun 2022.
DETERMINAN KUALITAS LAPORAN KEUANGAN KOPERASI WANITA DI KABUPATEN SUMENEP
Authors: Nurjannah Evira Afif , Nawirah Nawirah 
Published: December 2024

This research aims to test the influence of understanding SAK ETAP cooperative accounting, the quality of human resources, education level, the use of information technology and integrity on the quality of financial reports of womenâ€™s cooperatives in Sumenep district. With this research, it is expected to be additional information and input for womenâ€™s cooperatives to further improve the quality of their financial statements. This study builds on previous research by adding integrity variables and object used by the Sumenep Regency womenâ€™s cooperative because. The population of this study is a womenâ€™s cooperative registered in the KEMENKOPUKM with a sample of 74 respondents and analysis data using SPSS 26.0 software. The results of this study are variables of understanding accounting for SAK ETAP cooperatives and the quality of human resources have positive and significant effect on the quality of financial statements, while the level of education, the use of information technology and integrity do not affect the quality of financial statements in womenâ€™s cooperatives.
Composição do leite de vacas crioulas de origem patagônica. Resultados preliminares
Authors: Fránciga Gonzalo Gastón , Benavídez Carlos , Borches Axel , López Gustavo , Martínez Ruben Darío 
Published: December 2024

Las primeras vacas lecheras argentinas fueron de raza criolla. Se distribuyeron en todas las provincias, aportando leche para consumo directo y materia prima para manteca, dulce de leche y quesos regionales. Con la importación de razas lecheras especializadas a fines del siglo XIX, perdieron protagonismo como lecheras. La Facultad de Ciencias Agrarias de la UNLZ, posee un plantel de bovinos criollos de origen patagónico, procedentes del Parque Nacional Los Glaciares, que ha evolucionado en condiciones de asilvestramiento y se adaptó a un clima frío y húmedo. No encontramos ningún trabajo que describa la composicion láctea de las vacas de nuestra raza pionera. Se ordeñaron seis vacas criollas de origen patagónico de cinco años de edad promedio y dos vacas Holando Argentino como testigos. Durante el ordeñe se mantuvieron sobre un pastizal natural serrano en la escuela agropecuaria Nro 1 de Tornquist. Al cuarto día postparto los terneros se destetaron. Las vacas se ordeñaron diariamente en tambo mecánico en horas del mediodía, suministrándoles a cada vaca durante el ordeñe 2,35 kg de suplemento alimentario. El control lechero regional, tomó muestras de leche de las ocho vacas, siendo analizadas en el laboratorio Lacle, utilizando los procedimientos habituales. Los resultados promedios expresados en gr/100ml para las vacas Criollas y para la Holando Argentino fueron respectivamente: Grasa: 0,94 y 2,76. Proteína: 7,38 y 5,43. Lactosa: 1,19 y 3,93. Sólidos Totales: 8,56 y 12,65. Sólidos No Grasos: 8,12 y 9,89. En promedio las Criollas patagónicas mostraron mayor porcentaje de proteína y menor grasa y lactosa.
Socket Shield Technique in Immediate Implantation of the Maxillary Lateral Incisor. Clinical Case
Authors: Huseynli R.A. , Panahov N.A. 
Published: December 2024

Alveolar bone resorption is a natural process that occurs over time after tooth extraction, and is a challenge for implant treatment, complicating the process of prosthetic rehabilitation. That is why methods of immediate implant placement, while maintaining the anatomical parameters of the socket, are very popular these days. With this method of treatment, a reduction in dimensional changes associated with extraction is achieved. One of these methods is the Socket Shield Technique (SST). This is an effective way to preserve the anatomical contour of the alveolar ridge, improving aesthetic results. Another very important advantage of this technique is the fact that even with a thickness of less than 1 mm. buccal bone, the anatomical parameters of the socket can be preserved for many years. This case report presents a 22-year-old female patient with a fractured upper lateral incisor. The socket shield technique was chosen based on the clinical findings from the cone beam computed tomography (CBCT) scan. The temporary restoration was provided immediately to preserve soft tissue integration. A 3 years clinical observations, suggests that the socket shield technique is a useful method for preserving hard and soft tissue structures, thereby improving aesthetic outcomes.
Резорбция альвеолярной кости – естественный процесс, который происходит с течением времени после удаления зуба и является проблемой для имплантологического лечения, усложняя процесс протезной реабилитации. Вот почему методы немедленной установки имплантатов с сохранением анатомических параметров лунки очень популярны в наши дни. При таком методе лечения достигается уменьшение размерных изменений, связанных с удалением. Одним из таких методов является техника Socket Shield. Это эффективный способ сохранения анатомического контура альвеолярного гребня, улучшающий эстетические результаты. Еще одним очень важным преимуществом этой техники является тот факт, что даже при толщине менее 1 мм щечной кости анатомические параметры лунки могут сохраняться в течение многих лет. В статье представлен клинический случай наблюдения 22-летней пациентки с переломом верхнего бокового резца. Методика Socket Shield была выбрана на основе клинических результатов сканирования с помощью конусно-лучевой компьютерной томографии. Временная реставрация была выполнена немедленно для сохранения интеграции мягких тканей. Клинические наблюдения в течение 3 лет показывают, что метод Socket Shield является полезным для сохранения твердых и мягких тканей, тем самым улучшая эстетические результаты.
Appréciation du caractère proportionné (ou non) de la destruction d’un ouvrage contesté
Authors: Milleville Sébastien 
Published: December 2024

CA Grenoble, 1re chambre, 20 février 2024 Selon l’expert judiciaire, le mur litigieux est exempt de toute malfaçon de nature à en fragiliser la construction et à représenter un danger pour les personnes ou pour les biens. La cause du trouble anormal de voisinage occasionné par son existence réside dans son aspect esthétique, il y a lieu d’infirmer le jugement déféré en ce qu’il a ordonné la démolition de cet ouvrage, ce mode de réparation s’avérant être disproportionné. CA Grenoble, 1re chambre, 28 mai 2024La construction nouvelle du chalet de 80 m2 édifiée sans permis de construire au regard de son refus du 19 avril 2021 est illicite et la commune de [Localité 5] est fondée à en demander la démolition. Pour s’opposer à cette démolition, les époux [N] font valoir l’atteinte disproportionnée au droit au domicile et au droit à la vie familiale visés dans l’article 8 de la convention de sauvegarde des droits de l’homme et des libertés. Toutefois, alors qu’il est établi que les époux [N] sont domiciliés sur la commune de [Localité 6], il n’est justifié d’aucune atteinte disproportionnée à un domicile et une vie familiale qui n’existent pas sur la commune de [Localité 5] alors qu’est en jeu la protection de la vie humaine au regard des risques d’inondation.
Compétence du président de chambre pour prononcer l’irrecevabilité de l’appel : c’est oui ou bien c’est non ?
Authors: Vigouroux Naomi 
Published: December 2024

En vertu de l’article 905‑2 ancien du Code de procédure civile, l’irrecevabilité de l’appel tirée de sa tardiveté ne peut être prononcée par le président de chambre dans une procédure à bref délai. Cette interprétation du texte a pris fin le 1er septembre 2024 du fait de l’entrée en vigueur du décret de simplification du 29 décembre 2023. Toutefois, l’arrêt rendu le 16 janvier 2024 conserve un intérêt en ce qu’il estime que l’extension de la compétence du président nuit à la célérité et l’efficacité de la procédure à bref délai. Or, le nouvel article 906‑3 étend les pouvoirs du président.