bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMPARISON OF VIDEO CALL INSTRUCTIONS AND VOICE CALLS IN INDONESIAN LANGUAGE ON CHEST COMPRESSION ONLY HAND POSITION
Authors: Maulidah  , Virdiyanti Ruri , Wahid Abdurahman , Rahmawati Emelia 
Published: December 2024

Background: Out of Hospital Cardiac Arrest (OHCA) or cardiac arrest events that occur outside the hospital are the focus of world health problems which is often threaten a person's life. First aid that must be given quickly and precisely is Cardio Pulmonary Resuscitation (CPR). The rapid initiation of CPR with correct hand positioning by laypersons in cases of OHCA is critical for improving survival rates.
Objectives: The purpose of this study was to compare the accuracy of the hand position of the lay rescuer when performing chest compressions only which was instructed through video calls and voice calls in Indonesian Language.
Methods: This research was an experimental study. Sampling using probability sampling. The sample consists of 40 people who were divided into 2 groups, namely the instruction group via video call and voice call.
Results: The results show that in the video call group there were as many as 9 people (45%) who performed hand placement during CPR correctly, while in the voice call group there were 13 people (65%). The statistical results using Mann Whitney test showed that there was no significant difference between video call and voice calls instructions in Language (p = 0.209).
Conclusion: It needs the training for Emergency Medical Services (EMS) operator officers prior to conducting the study and the near real situations as the original incident in order to get more effective on performing chest compressions.
In silico analysis of lncRNA-miRNA-mRNA signatures related to Sorafenib effectiveness in liver cancer cells
Authors: de la Cruz-Ojeda Patricia , Parras-Martínez Ester , Rey-Pérez Raquel , Muntané Jordi 
Published: December 2024

BACKGROUND
Hepatocellular carcinoma (HCC) is the most common subtype of primary liver cancer with varied incidence and epidemiology worldwide. Sorafenib is still a recommended treatment for a large proportion of patients with advanced HCC. Different patterns of treatment responsiveness have been identified in differentiated hepatoblastoma HepG2 cells and metastatic HCC SNU449 cells.
AIM
To define the long non-codingRNA-microRNA-mRNA (lncRNA-miRNA-mRNA) predicted signatures related to selected hallmarks of cancer (apoptosis, autophagy, cell stress, cell dedifferentiation and invasiveness) in RNAseq studies using Sorafenib-treated HepG2 and SNU449 cells. Various available software analyses allowed us to establish the lncRNA-miRNA-mRNA regulatory axes following treatment in HepG2 and SNU449 cells.
METHODS
HepG2 and SNU449 cells were treated with Sorafenib (10 μmol/L) for 24 hours. Total RNA, including small and long RNA, was extracted with a commercial miRNeasy kit. RNAseq was carried out for the identification of changes in lncRNA-miRNA-mRNA regulatory axes.
RESULTS
MALAT, THAP9-AS1 and SNGH17 appeared to coordinately regulate miR-374b-3p and miR-769-5p that led to upregulation of SMAD7 , TIRARP , TFAP4 and FAXDC2 in HepG2 cells. SNHG12, EPB41 L4A-AS1, LINC01578, SNHG12 and GAS5 interacted with let-7b-3p, miR-195-5p and VEGFA in SNU449 cells. The axes MALAT1/hsa-mir-374b-3p/SMAD7 and MALAT1/hsa-mir-769-5p/TFAP4 were of high relevance for Sorafenib response in HepG2 cells, whereas PVT1 /hsa-miR-195-5p/VEGFA was responsible for the differential response of SNU449 cells to Sorafenib treatment.
CONCLUSION
Critical lncRNAs acting as sponges of miRNA were identified that regulated mRNA expression, whose proteins mainly increased the antitumor effectiveness of the treatment (SMAD7 , TIRARP , TFAP4 , FAXDC2 and ADRB2 ). However, the broad regulatory axis leading to increased VEGFA expression may be related to the side effect of Sorafenib in SNU449 cells.
PENGARUH MODEL PEMBELAJARAN CONTEXUAL TEACHING LEARANING TERHADAP HASIL BELAJAR SISWA PADA MATA PELAJARAN PKN KELAS IV SEKOLAH DASAR
Authors: Lay Abir Yohindro , Naitili Cornelia Amanda , Nahak Roswita Lioba 
Published: December 2024

PKn learning is expected to be a vehicle for students to learn about themselves and the surrounding environment as well as prospects for further development in applying it in daily life. However, there are still many students who lack mastery of the material and obtain scores that have not reached the KKTP. This happens because the learning model used is usually a conventional learning model. In addition, it also identifies problems, namely First, the learning outcomes of PKN students have not reached KKTP, second, teachers tend to use conventional learning models where teachers teach more oriented to lecture methods so that learning is more teacher-centered. Third, the teacher's lack of attention to the student's ability to receive the material because it is chasing time so that the material is completed quickly. The purpose of this study is to determine the influence of the continuous teaching learning model on the learning outcomes of PKn in grade IV students of Oepura 4 Multi-level SDI, Kupang City. This type of research is a quantitative research classified as Quasi Experimental research, using a pretest posttest control group design. The sampling technique uses a saturated sampling technique with a sample of 30 respondents. The instruments used in this study are tests and documentation. The data was analyzed using data normality tests, homogination tests, linearity tests, and hypothesis tests. The results showed that the average posttest score of the experimental class and the control class posttest using the t-test was 78.33 > 1.50 with a difference of 15.82. Furthermore, through hypothesis testing (Independent Samples Tests) it was shown that the value of sig. (2-tailed) t-test for Equality of Means of 0.000<0.05 means that H0 is rejected and Ha is accepted. The conclusion of this study is the application of the significant influence of the contexual teaching learning model on the learning outcomes of PKn students in grade IV of SD Inpres Berstrata Oepura 4, Kupang City.
The Subparsec-scale Structure and Evolution of Centaurus A. III. A Multi-epoch Spectral and Polarimetric VLBA Study
Authors: Prabu S. , Tingay S. J. , Bahramian A. , Miller-Jones J. C. A. , Wood C. M. , O’Sullivan S. P. 
Published: December 2024

Abstract
The Centaurus A radio galaxy, due to its proximity, presents itself as one of the few systems that allow the study of relativistic jet outflows at subparsec distances from the central supermassive black holes, with high signal to noise. We present the results from the first multi-epoch spectropolarimetric observations of Centaurus A at milliarcsecond resolution, with a continuous frequency coverage of 4.59−7.78 GHz. Using a Bayesian framework, we perform a comprehensive study of the jet kinematics, and discuss aspects of the jet geometry, including the jet inclination angle, jet opening angle, and the jet expansion profile. We calculate an upper limit on the jet’s inclination to the line of sight to be <25°, implying the lower limit on the intrinsic jet speed to be 0.2c. On the observed very long baseline array scales, we detect new jet components launched by the central engine since our previous study. Using the observed frequency-dependent core shift in Centaurus A, we find the jet to have reached constant bulk speed and conical outflow at the regions probed by the base of the jet at 7.78−4.59 GHz, and we also estimate the location of the central black hole further upstream. Through polarimetric analysis (by applying rotation measure synthesis for the first time on very long baseline interferometry data), we find evidence to suggest the possible onset of acceleration toward the leading edge of Centaurus A’s subparsec-scale jet studied here.
A Spectroscopic and Interferometric Study of W Serpentis Stars. I. Circumbinary Outflow in the Interacting Binary W Serpentis
Authors: Shepard Katherine , Gies Douglas R. , Schaefer Gail H. , Anugu Narsireddy , Baron Fabien R. , Lanthermann Cyprien , Monnier John D. , Kraus Stefan , ten Brummelaar Theo 
Published: December 2024

Abstract
W Serpentis is an eclipsing binary system and the prototype of the Serpentid class of variable stars. These are interacting binaries experiencing intense mass transfer and mass loss. However, the identities and properties of both stars in W Ser remain a mystery. Here, we present an observational analysis of high-quality, visible-band spectroscopy made with the Apache Point Observatory 3.5 m telescope and Astrophysical Research Consortium Echelle Spectrograph spectrograph plus the first near-IR, long-baseline interferometric observations obtained with the Center for High Angular Resolution Astronomy Array. We present examples of the appearance and radial velocities of the main spectral components: prominent emission lines, strong shell absorption lines, and weak absorption lines. We show that some of the weak absorption features are associated with the cool mass donor, and we present the first radial velocity curve for the donor star. The donor’s absorption lines are rotationally broadened, and we derive a ratio of donor to gainer mass of 0.36 ± 0.09 based on the assumptions that the donor fills its Roche lobe and that it rotates synchronously with the orbit. We use a fit of the All-Sky Automated Survey light curve to determine the orbital inclination and mass estimates of 2.0M
⊙ and 5.7M
⊙ for the donor and gainer, respectively. The partially resolved interferometric measurements of orbital motion are consistent with our derived orbital properties and the distance from Gaia EDR3. Spectroscopic evidence indicates that the gainer is enshrouded in an opaque disk that channels the mass transfer stream into an outflow through the L3 region and into a circumbinary disk.
La montée des embauches en CDD court en France depuis 2000
Authors: Baguelin Olivier 
Published: December 2024

La plupart des explications de la montée des contrats à durée déterminée (CDD) courts (moins d’un mois) mettent en cause certains dispositifs, comme le CDD d’usage, les règles d’accès à l’assurance chômage, l’activité réduite ou les droits rechargeables. L’évolution de l’emploi et sa recomposition sectorielle peuvent pourtant à elles seules jouer un rôle considérable dans la multiplication des CDD courts. La présente étude en propose une quantification systématique, entre 2000 et 2019, à partir de statistiques sectorielles Acoss-Urssaf. Trois périodes aux contextes conjoncturels et réglementaires distincts sont considérées : 2000-2009 ; 2009-2014 ; 2014-2019. L’analyse permet de repérer pour certains secteurs, notamment entre 2009 et 2014, une utilisation défensive des CDD courts associée à un emploi en repli. Mais la montée de ce type de contrats est surtout forte dans les secteurs dont l’emploi est en expansion. Quatre tendances sectorielles peuvent être associées à cela : le développement d’activités motivées par un produit occasionnel (spectacle, événementiel, etc.), qui justifie une flexibilité d’usage ; la réponse aux enjeux du vieillissement de la population à partir d’un emploi de mauvaise qualité (médico-social, aide à domicile, etc.), qui démultiplie les absences au travail ; la montée de la sous-traitance (sécurité, propreté, etc.), qui s’accompagne d’une précarisation de l’emploi ; le développement de la sphère présentielle (commerce, restauration, etc.), qui sollicite particulièrement l’emploi ponctuel. Rapporté à ces tendances alimentant la montée des CDD courts, le rôle de stratégies de gestion de l’emploi ajustées à un environnement réglementaire évolutif apparaît limité : c’est particulièrement clair pour le CDD d’usage ou l’activité réduite. De façon générale, les changements de pratiques sont liés aux conjonctures sectorielles.
Précarité, sur-emploi ou discontinuité ?
Authors: Vivès Claire , Remillon Delphine 
Published: December 2024

Cet article étudie la situation spécifique des salarié·es de 50 ans et plus en contrats courts pour comprendre leurs trajectoires, leurs vécus, les spécificités des obstacles rencontrés et des ressources mobilisées. Outre un éclairage quantitatif apporté sur notre matériau qualitatif via la mobilisation de l’enquête Emploi, la spécificité de notre démarche réside dans l’analyse croisée des éléments relevant de l’emploi et du chômage, des situations objectives et des vécus. Nous décrivons d’abord les principales caractéristiques socioprofessionnelles des seniors en contrats courts. Nous distinguons ensuite trois types de trajectoires. Deux premières configurations peu connues apparaissent, où contrats courts ne riment pas avec précarité pour les seniors : le cumul d’un emploi stable avec des contrats courts ; des carrières en contrats courts dans des secteurs où ceux-ci sont la norme. Le troisième type de parcours concerne les seniors dont les trajectoires sont marquées par la précarité et qui aspirent à travailler davantage, en contrat à durée indéterminée et avec des conditions de travail moins pénibles. Enfin, nous analysons les ressources et les obstacles spécifiques aux seniors en contrats courts par rapport à des salarié·es plus jeunes dans la même situation.
Le café comme équipement cinématographique. Commerce et localisation du spectacle cinématographique en province à la Belle Époque
Authors: Leveratto Jean-Marc , Montebello Fabrice , Stotzky Pierre 
Published: December 2024

Loin d’être limitée à l’industrie du café-concert, à des lieux spécialisés dans l’organisation de concerts et de représentations, une fonction ludique et esthétique a été assurée en France par les cafés de quartiers et de province. Bien avant l’invention de la radio et du juke-box, ceux-ci furent des vecteurs de diffusion de ses produits pour l’industrie musicale moderne, tant par le biais des machines – le piano mécanique, le gramophone – que par celui des musiciens et des chanteurs chargés de fournir un plaisir musical à la clientèle, assise ou dansante. Les cafés de la Belle É poque ont joué le même rôle pour l’industrie cinématographique : déterminant mais peu étudié, sauf à Paris. La filiation entre la sortie cinématographique et la sortie au café-concert, accessible à la grande partie de la population française exclue de la sortie théâtrale, gêne la reconnaissance du rôle des cafés ordinaires dans la formation du public cinématographique en France. Par ailleurs, la valorisation quasi exclusive de la fête foraine comme moyen de popularisation de la technique cinématographique en province explique que, bien que « lieu de mémoire » et étudié comme tel, le café n’ait pas été scruté par les historiens en tant que lieu de mémoire cinématographique.
Enhancing higher education performance: Transformational, transactional and agile leadership
Authors: Samodien Mahir , Du Plessis Marieta , Van Vuuren Carel J. 
Published: December 2024

Orientation: Leadership styles have a significant influence on institutional performance. Transactional, transformational and agile leadership styles demonstrate positive organisational outcomes.Research purpose: This study examines how transactional, transformational, and agile leadership styles influence and predict institutional performance within South African higher education. By identifying the most effective leadership approach, the research offers recommendations to enhance leadership strategies in the sector.Motivation for the study: These leadership styles were selected because of their relevance in navigating the structural, innovative and adaptive needs of higher education institutions. Understanding their impact will help shape more effective leadership interventions.Research approach/design and method: A quantitative, correlational design was used. The Multifactor Leadership Questionnaire (MLQ), Agile Leadership Questionnaire and Institutional Performance Questionnaire were administered to a convenience sample of 224 staff across five public institutions in South Africa.Main findings: All three leadership styles positively and significantly influenced institutional performance. Transformational and agile leadership showed the strongest ability to explain the variance in performance, with transformational leadership explaining the most variance.Practical/managerial implications: Effective leadership is critical for performance in South African higher education. Leadership training should develop transformational and agile leadership behaviours.Contribution/value-add: The findings highlight the importance of leadership style for institutional performance and the need for tailored leadership developmental programmes in academia.
Fixed erythematous plaque: An interesting case report
Authors: Supekar Bhgyashree B. , Rokade Pallavi R. , Wankahde Vaishali H. , Mukhi Jayesh I. , Nama Piyush 
Published: December 2024

Abstract
Docetaxel is a chemotherapeutic agent used to treat multiple cancers, including metastatic or locally advanced breast cancer and advanced ovarian cancer. It has been attributable to various cutaneous adverse drug reactions including acral erythema, supravenous hyperpigmentation, and erythema multiforme. We report a case of fixed erythrodysesthesia plaque secondary to docetaxel infusion after the third cycle in a 60-year-old female.
Cardioprotective effect of S-adenosyl L-methionine due to antioxidant and anti-inflammatory properties on isoproterenol-induced chronic heart failure in Wistar rats
Authors: Jalgaonkar Sharmila Vinayak , Tripathi Raakhi , Kurhade Komal Gorakshanath , Chaudhari Pradeep , Mohanty Bhabani Shankar , Vaideeswar Pradeep 
Published: December 2024

Abstract

OBJECTIVES:
The development and progression of chronic heart failure (CHF), hypertrophy, and remodeling strongly correlate with myocardial inflammation and oxidative stress. S-adenosylmethionine (SAMe), available as a dietary supplement, exerts anti-inflammatory and antioxidant effects. Previous reports show that by regulating angiogenesis and fibrosis, S-adenosyl-L-methionine improves ventricular remodeling. The study objectives were to investigate the cardioprotective effect of SAMe in isoproterenol (ISO)-induced CHF and explore the anti-inflammatory and antioxidant properties of SAMe in this model.

METHODOLOGY:
After animal ethics permission, CHF was induced using ISO of 10 mg/kg for 14 consecutive days in 24 Wistar rats. There were four groups of six rats in each group: Sham Control, Disease Control (DC), ISO + SAMe 100 mg, and ISO + SAMe 200 mg. The variables assessed were heart to body weight ratio (HW/BW mg/g), bio-distribution of Flourine 18-Fluorodeoxyglucose (18F-FDG) in heart tissue, tumor necrosis factor-α (TNF-α) and glutathione (GSH) levels in heart tissue, histopathology, and positron emission tomography imaging.

RESULTS:
SAMe in ISO-induced CHF animals showed a significant decrease in the HW/BW compared to DC group (P < 0.001). 18F-FDG uptake was significantly reduced by SAMe in CHF-induced rats compared to DC rats for both doses (P < 0.001). SAMe showed significantly better values of both TNF-α and GSH than the DC group in both doses (P < 0.001). SAMe in both doses showed multifocal necrosis with scarring and minimal inflammatory cells.

CONCLUSION:
SAMe exerts a cardioprotective effect on ISO-induced CHF in rats because of its antioxidant and anti-inflammatory properties.
Late Onset Bradycardia
Authors: Dashore Shuken , Pande Sushil , Borkar Milind , Pande Abhishek 
Published: December 2024

Introduction:
High-dose corticosteroids are used for various autoimmune and inflammatory diseases. When supra-pharmacologic doses of corticosteroids are used intravenously for the treatment of immunobullous diseases such as pemphigus, it is likely to be associated with side effects such as electrolyte disturbances, hypertension, and psychosis.

Case Reports:
In these case series, we report five patients receiving high-dose of dexamethasone with or without cyclophosphamide pulse, developing an unusual form of late onset bradycardia. Details of these patients developing bradycardia after dexamethasone pulse therapy are presented here. In all of these cases, bradycardia can be attributed to high-dose intravenous dexamethasone therapy. Bradyarrhythmias and sinus bradycardia may occur as an adverse effect of pulse therapy.

Conclusion:
Late onset of bradycardia is usually delayed in comparison to steroid infusion and frequently not apparent even after the 3rd day. Bradycardia may be associated with dizziness and may lead to fall and unnecessary trauma. Dermatologists should be aware of this complication, and timely referral to physician is essential.
L’algorithme : pourquoi et comment le définir pour l'enseigner
Authors: Beffara Emmanuel 
Published: December 2024

The question of the definition of what is an algorithm is recurrent. It is found in teaching, at different levels and particularly in secondary education because of the recent evolutions in high school, with immediate consequences in higher education. It is found in mediation, with the different meanings that the word “algorithm” is charged with in the media space. It is also found in research, with issues in different branches of computer science, from foundations in computability and complexity to applications in big data. Beyond the issue of definition, it is the raison d’être of the notion of algorithm that should be questioned: what do we want to do with it and what is at stake? It is by trying to specify this that we can identify didactic elements that are likely to help teach the algorithm, in interaction with mathematics or not, and to different audiences.La question de la définition de ce qu’est un algorithme est récurrente. Elle se trouve dans l’enseignement, à différents niveaux et singulièrement le secondaire du fait des évolutions récentes au collège et au lycée, avec des conséquences immédiates dans le supérieur. Elle se trouve dans la médiation, avec les différents sens dont le mot « algorithme » est chargé dans l’espace médiatique. Elle se trouve aussi dans la recherche, avec des enjeux dans différentes branches de l’informatique, depuis les fondements en calculabilité et complexité jusqu’aux applications dans le traitement des données massives. Au delà du problème de la définition, c’est la raison d’être de la notion d’algorithme qu’il convient de questionner : que veut-on en faire et de quels enjeux est-elle le nom ? C’est en cherchant à préciser cela que l’on peut identifier les éléments didactiques susceptibles d’enseigner l’algorithme, en interaction avec les mathématiques ou pas et à différents publics.