bluuebunny/crossref_metadata_2025_split huggingface dataset:
Avaliação da produtividade dos criadouros do Aedes aegypti (L.) e Aedes albopictus (Skuse) através dos dados da vigilância em Parati – RJ.
Authors: Wermelinger Eduardo Dias , Almeida Adilson Benedito , Benigno Ciro Villanova , Ferreira Aldo Pacheco 
Published: June 2020

Esse estudo avaliou a produtividade dos criadouros de Aedes aegypti (Linnaeus) e Aedes albopictus (Skuse) no município de Parati através dos dados da vigilância entomológica obtidos pelos métodos preconizados pelo Programa Nacional de Controle da Dengue (PNCD). O maior número de pupas de A. aegypti foi coletado nos ralos (31%), garrafas e latas (23%); e com A. albopictus o maior número foi nas garrafas, latas (24%) e vasos de planta (21%). Do total de pupas obtidas, 84,3% e 79,3% das pupas de A. aegypti e A. albopictus respectivamente foram coletadas em pequenos reservatórios: garrafas, vasos de plantas, pneus, bromélias, oco de árvores e ralos. Essas produtividades contradizem a literatura e podem ser explicadas pelas limitações de acesso aos grandes reservatórios e falha na capacitação dos agentes. Esse estudo chama atenção para a importância que os pequenos reservatórios podem ter na densidade do vetor no meio urbano nacional e conclui que a metodologia de vigilância entomológica usada tem sido ineficaz para identificar os grandes e mais produtivos criadouros. Essa conclusão sugere que essa ineficácia pode ser um fator importante pelos insucessos no combate a dengue no Brasil.
Evaluation of Breeding Productivity from Surveillance Data for Aedes aegypti (Linnaeus) and Aedes albopictus (Skuse) in Parati, RJ, Brazil
Abstract. This study evaluated the pupa-productivity of the entomologic surveillance according methodology used by the official Program for Dengue Control in Brazil (PDCB) for Aedes aegypti (Linnaeus) and Aedes albopictus (Skuse) in Parati, RJ, Brazil. The highest number of A. aegypti pupae were found in drains (31%), bottles and cans (23%); and the highest number of A. albopictus pupae were found in bottles and cans (24%), and plant vases (21%). Of the total pupae identified 84.3% and 79.3% of A. aegypti and A. albopictus respectively were collected in small receptacles: bottles, plants vase, tires, bromeliads and tree holes. These productivities are not supported by literature and can be explained by the restrictions of access for the bigger receptacles and lack of training of the agents. The study points out the importance which the small receptacles can have on vector densities in urban environment despite of their productivity and conclude that the entomology surveillance methodology for dengue used in PDCB has no efficacy to identify the bigger and more productive receptacles. This conclusion suggests that this inefficacy can be an important factor for the failures on dengue vector control in Brazil.
The Last Mile Matters: Impact of Dockless Bike Sharing on Subway Housing Price Premium
Authors: Chu Junhong , Duan Yige , Yang Xianling , Wang Li 
Published: June 2020

Dockless bike sharing provides a convenient and affordable means of transport for urban residents. It solves the “last-mile problem” in public transport by reducing the travel cost between home and subway stations and thus increasing the attractiveness of distant apartments. This may affect the relationship between housing price and distance to subway and reduce the price premium enjoyed by proximate apartments. Using resale apartment data in 10 major cities in China, a difference-in-differences approach at the apartment level, and a two-step estimator at the city-month level, we find that the entry of bike sharing reduces the housing price premium by 29% per km away from a subway station. The effect is equivalent to a reduction of 1,893–2,127 CNY (282–317 USD) in commuting costs per household per annum over 30 years. The effect is driven by a relative increase in the listing price of, and in the demand for, apartments distant from vis-à-vis proximate to subway stations. This paper was accepted by Juanjuan Zhang, marketing.
Anti-fibrotic effects of the antihistamine ketotifen in a rabbit model of arthrofibrosis
Authors: Tibbo Meagan E , Limberg Afton K , Salib Christopher G , Turner Travis W , McLaury Alex R , Jay Anthony G , Bettencourt Jacob W , Carter Jodi M , Bolon Brad , Berry Daniel J , Morrey Mark E , Sanchez-Sotelo Joaquin , van Wijnen Andre J , Abdel Matthew P 
Published: June 2020

Aims Arthrofibrosis is a relatively common complication after joint injuries and surgery, particularly in the knee. The present study used a previously described and validated rabbit model to assess the biomechanical, histopathological, and molecular effects of the mast cell stabilizer ketotifen on surgically induced knee joint contractures in female rabbits. Methods A group of 12 skeletally mature rabbits were randomly divided into two groups. One group received subcutaneous (SQ) saline, and a second group received SQ ketotifen injections. Biomechanical data were collected at eight, ten, 16, and 24 weeks. At the time of necropsy, posterior capsule tissue was collected for histopathological and gene expression analyses (messenger RNA (mRNA) and protein). Results At the 24-week timepoint, there was a statistically significant increase in passive extension among rabbits treated with ketotifen compared to those treated with saline (p = 0.03). However, no difference in capsular stiffness was detected. Histopathological data failed to demonstrate a decrease in the density of fibrous tissue or a decrease in α-smooth muscle actin (α-SMA) staining with ketotifen treatment. In contrast, tryptase and α-SMA protein expression in the ketotifen group were decreased when compared to saline controls (p = 0.007 and p = 0.01, respectively). Furthermore, there was a significant decrease in α-SMA (ACTA2) gene expression in the ketotifen group compared to the control group (p < 0.001). Conclusion Collectively, these data suggest that ketotifen mitigates the severity of contracture formation in a rabbit model of arthrofibrosis. Cite this article: Bone Joint Res 2020;9(6):302–310.
Decellularized porcine xenograft for anterior cruciate ligament reconstruction
Authors: Hexter Adam T. , Hing Karin A. , Haddad Fares S. , Blunn Gordon 
Published: June 2020

Aims To evaluate graft healing of decellularized porcine superflexor tendon (pSFT) xenograft in an ovine anterior cruciate ligament (ACL) reconstruction model using two femoral fixation devices. Also, to determine if pSFT allows functional recovery of gait as compared with the preoperative measurements. Methods A total of 12 sheep underwent unilateral single-bundle ACL reconstruction using pSFT. Two femoral fixation devices were investigated: Group 1 (n = 6) used cortical suspensory fixation (Endobutton CL) and Group 2 (n = 6) used cross-pin fixation (Stratis ST). A soft screw was used for tibial fixation. Functional recovery was quantified using force plate analysis at weeks 5, 8, and 11. The sheep were euthanized after 12 weeks and comprehensive histological analysis characterized graft healing at the graft-bone interface and the intra-articular graft (ligamentization). Results The pSFT remodelled into a ligament-like structure and no adverse inflammatory reaction was seen. The ground reaction force in the operated leg of the Endobutton group was higher at 11 weeks (p < 0.05). An indirect insertion was seen at the graft-bone interface characterized by Sharpey-like fibres. Qualitative differences in tendon remodelling were seen between the two groups, with greater crimp-like organization and more aligned collagen fibres seen with Endobutton fixation. One graft rupture occurred in the cross-pin group, which histologically showed low collagen organization. Conclusion Decellularized pSFT xenograft remodels into a ligament-like structure after 12 weeks and regenerates an indirect-type insertion with Sharpey-like fibres. No adverse inflammatory reaction was observed. Cortical suspensory femoral fixation was associated with more enhanced graft remodelling and earlier functional recovery when compared with the stiffer cross-pin fixation.
Study on Anisotropic Mechanical Properties and Failure Modes of Layered Rock Using Uniaxial Compression Test
Authors: Zuo Shuangying , Zhao Donglei , Zhang Jing , Chen Shiwan 
Published: June 2020

Abstract
To reveal the failure mechanisms and strength anisotropy of layered rock, uniaxial compression tests were conducted on dolomite samples with seven different bedding dip angles, and the compressive strength and the Young’s modulus with dip angle β were analyzed. Meanwhile, five failure modes (rock tensile cracking, rock shearing failure, bedding cracking, bedding sliding failure, and rock bending) were observed from laboratory phenomena, and the corresponding anisotropy constitutive model was further developed based on the transversely isotropic model and the plastic mechanics flow rules. Finally, the self-defined anisotropic constitutive model was coded in FLAC3D to carry out a numerical simulation of uniaxial compression. Results showed that the numerical simulation agreed well with experimental tests results, which proved that the assumption of a transversely isotropic model was reasonable. Furthermore, the proposed model could be applied to evaluate the stability of rock slopes with different bedding dip angles, and the bedding dip angle played an important role on failure modes and the stability of slope.
Constructing the Local Wisdom Values of the Yel Lim Culture as a Historical Learning Source
Authors: Ufie Agustinus , Ritiauw Samuel P , Kubangun Nur Aida 
Published: June 2020

This study describes the living tradition of the indigenous people who live in a cluster of small islands in the southeast and south of the Maluku Islands, Indonesia, namely the Kei People. They have a robust local culture that influences in guiding and directing them to build social relations amid the onslaught of globalization with various attributes modernity that continues to go back and forth. The Yel Lim Culture, as the symbol and the identity of the Kei Community, radiates messages of humanity, tolerance, solidarity, and friendship, based on the life principle of siblings regardless of differences in ethnicity, religion, and race, it must continue to be preserved. To discover and then to elaborate on the main essence of the Yel Lim culture in the life of the Kei Community, a descriptive-analytical approach, as part of qualitative research, was taken. The results of this research showed that the Yel Lim Culture up to now was still being carried out because these cultural values were the guide, a guideline in realizing social order as a society that lived and developed in the Kei Islands. Observing the current social reality, then constructing Yel Lim's cultural values as a source in history class is very important in preparing future generations who have integrity and youthful identity, which is not easily trapped in various negative things because it continues to lean on local cultural values as their identity. Thus, the future generation that we build is the generation that is civilized and has virtuous and noble character as well. Kajian ini mendeskripsikan tradisi masyarakat adat yang tinggal di kepulauan Kei Maluku Tenggara, dan memiliki budaya lokal dalam menuntun, mengarahkan mereka membangun relasi sosial walaupun ditengah-tengah gempuran arus modernisasi. Budaya Yel Lim sebagai simbol, identitas masyarakat Kei memancarkan pesan kemanusiaan, persaudaraan, toleransi, solidaritas dan silahturhami. Untuk menemukan, mempertahankan dan mengelaborasi budaya Yel Lim dalam kehidupan masyarakat Kei, sebagai salah satu sumber pembelajaran maka pendekatan deskriptif analitis sebagai bagian dari penelitian kualitatif ditempuh. Hasil penelitian ini memperlihatkan bahwa nilai-nilai budaya Yel Lim harus terus dimanifestasikan guna mewujudkan keteraturan sosial komunitas masyarakat adat Kei dari generasi ke generasi. Untuk itu, mengkonstruksi nilai-nilai budaya Yel Lim sebagai sumber pengembangan pembelajaran sejarah di Sekolah (SMP/SMA) sangatlah penting guna mempersiapkan generasi masa depan yang memiliki integritas, jati diri sehingga tidak muda terjerumus dalam berbagai hal negatif. Sehingga generasi masa depan yang kita bangun nantinya adalah generasi yang memiliki peradaban, budi pekerti luhur dan ahklak mulia.
La infancia en el retrato español. Una mirada a la empatía en la formación del profesorado de Educación Primaria
Authors: Muñoz García Gemma , Jiménez Pablo Esther 
Published: June 2020

Este trabajo pone de relieve el discurso de sectores olvidados por la historiografía y la Historia del Arte, en el marco de la formación del profesorado de Educación Primaria. Se ha seleccionado la infancia como realidad silenciada, y se ha analizado su representación en un género pictórico de gran potencial didáctico, el retrato. El estudio se ciñe especialmente a ejemplos representativos de la Edad Moderna, y más concretamente pertenecientes al ámbito español. Junto al potencial artístico del retrato, a la formación estética y metodológica, se pone en valor la empatía para trabajar y reflexionar sobre el pasado histórico.
IMPLEMENTASI PROGRAM ADIWIYATA MANDIRI DALAM MENANAMKAN KARAKTER PEDULI LINGKUNGAN SISWA
Authors: Nuzulia Sri , Sukamto Sukamto , Purnomo Agus 
Published: June 2020

AbstractAdiwiyata is an effort from the government to create a generation of people who are aware and have a sense of love and responsibility towards the environment. The adiwiyata program has become the flagship program implemented in SMP Negeri 15 Malang, as a basic curriculum in the learning and learning process based on environmental education that contains environmental care characters which are shown by respect for nature. The purpose of this study was to analyze the implementation of environmental care characters in SMP Negeri 15 Malang students. This study uses a qualitative approach to the type of descriptive research. Data collection techniques in research are interviews, observation, and documentation. The results showed that the adiwiyata program at SMP Negeri 15 Malang was implemented through extra-curricular activities and mandatory adiwiyata days, where students could care for the school environment to foster environmental attitudes and insights, while at the same time caring for the environment.Keywords : Adiwiyata, Implementation, Character Caring For The Environment Abstrak Adiwiyata merupakan upaya dari pemerintah untuk menciptakan generasi bangsa yang sadar dan memiliki rasa cinta dan tanggung-jawab terhadap lingkungan. Program adiwiyata menjadi program unggulan yang diterapkan di SMP Negeri 15 Malang, yakni sebagai kurikulum dasar dalam proses belajar dan pembelajaran berlandaskan pendidikan lingkungan hidup yang memuat karakter peduli lingkungan yang ditunjukkan dengan adanya penghargaan terhadap alam. Tujuan penelitian ini adalah untuk menganalisis implemetasi karakter peduli lingkungan pada siswa SMP Negeri 15 Malang. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian deskriptif. Teknik pengumpulan data dalam penelitian adalah wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan bahwa program adiwiyata di SMP Negeri 15 Malang diimplementasikan melalui kegiatan ekstra kurikuler dan hari wajib adiwiyata, di mana para siswa dapat merawat lingkungan sekolah guna menumbuhkan sikap dan wawasan lingkungan, sekaligus memiliki kepedulian terhadap lingkungan.Kata Kunci: Adiwiyata, Implementasi, dan Karakter Peduli Lingkungan.
Epithelial Vasopressin Type-2 Receptors Regulate Myofibroblasts by a YAP-CCN2–Dependent Mechanism in Polycystic Kidney Disease
Authors: Dwivedi Nidhi , Tao Shixin , Jamadar Abeda , Sinha Sonali , Howard Christianna , Wallace Darren P. , Fields Timothy A. , Leask Andrew , Calvet James P. , Rao Reena 
Published: June 2020

Significance Statement
In autosomal dominant polycystic kidney disease (ADPKD), progressive fibrosis contributes to renal failure, leading to ESKD. The vasopressin type-2 receptor (V2R) helps to regulate renal water homeostasis and stimulates cyst expansion in ADPKD. We discovered a novel pathogenic pathway behind V2R regulation of fibrosis in ADPKD kidneys. Epithelial V2R stimulation activates interstitial myofibroblasts, in a paracrine manner, in Pkd1 gene knockout (KO) mice. Pharmacologic inhibition and gene knockout studies indicated that V2R regulates myofibroblast activation by a yes-associated protein (YAP)– and connective tissue growth factor (CCN2)–dependent mechanism. The V2R-YAP-CCN2 molecular axis may present novel pharmacologic targets for control of fibrosis in ADPKD.

Background
Fibrosis is a major cause of loss of renal function in autosomal dominant polycystic kidney disease (ADPKD). In this study, we examined whether vasopressin type-2 receptor (V2R) activity in cystic epithelial cells can stimulate interstitial myofibroblasts and fibrosis in ADPKD kidneys.

Methods
We treated Pkd1 gene knockout (Pkd1KO) mice with dDAVP, a V2R agonist, for 3 days and evaluated the effect on myofibroblast deposition of extracellular matrix (ECM). We also analyzed the effects of conditioned media from primary cultures of human ADPKD cystic epithelial cells on myofibroblast activation. Because secretion of the profibrotic connective tissue growth factor (CCN2) increased significantly in dDAVP-treated Pkd1KO mouse kidneys, we examined its role in V2R-dependent fibrosis in ADPKD as well as that of yes-associated protein (YAP).

Results
V2R stimulation using dDAVP increased the renal interstitial myofibroblast population and ECM deposition. Similarly, conditioned media from human ADPKD cystic epithelial cells increased myofibroblast activation in vitro, suggesting a paracrine mechanism. Renal collecting duct–specific gene deletion of CCN2 significantly reduced cyst growth and myofibroblasts in Pkd1KO mouse kidneys. We found that YAP regulates CCN2, and YAP inhibition or gene deletion reduces renal fibrosis in Pkd1KO mouse kidneys. Importantly, YAP inactivation blocks the dDAVP-induced increase in myofibroblasts in Pkd1KO kidneys. Further in vitro studies showed that V2R regulates YAP by an ERK1/2-dependent mechanism in human ADPKD cystic epithelial cells.

Conclusions
Our results demonstrate a novel mechanism by which cystic epithelial cells stimulate myofibroblasts in the pericystic microenvironment, leading to fibrosis in ADPKD. The V2R-YAP-CCN2 cell signaling pathway may present a potential therapeutic target for fibrosis in ADPKD.
The Historical Account Of ʿabd Al-Jabbār Al-Hamadani’s Physicalist Conception Of Human Soul
Authors: Zafar Abdulbasit 
Published: June 2020

This study aims to go through Muʿtazilite understandings of a man briefly and expounds on Qadi ʿAbd al-Jabbār al-Hamadani’s (d. 1025) strong rejection of any non-physicalist view of man and his soul. Amongst the Mu'tazilite school prevailed three distinct views on man, hence of the soul; the non-physicalist tradition represented by Ibrāhīm b. Sayyār an-Naẓẓām (d. 836) who claimed that man is the dwelling soul in the human corpse. The dualist view as advocated by Muʿammar b. ʿAbbād (d. 830) who understood man as a combination of the material body and immaterial soul. The third view is the so-called materialist stance on the human being. Qadi ʿAbd al-Jabbār as one of the advocates of this view argues that man does not possess any immaterial or immortal soul. This paper proposes that such a peculiar view of man was the natural outcome of ʿAbd al-Jabbār’s cosmological setting and his sensitivity towards legal matters (talkif). ʿAbd al-Jabbār’s image of man does not need other; a soul, to make him will or capable of certain actions, for man is this corporeal body which could be seen in its actuality, and experienced in its totality. Therefore, he defines man (šaẖs) as a living being (ḥayy), having volition (murid), capable of acting voluntarily (qādir) and consequently entitles him with the responsibility for moral and religious obligations (al-mukallaf). It could be widely observed that Qadi, though admits the presence of soul in the body for its being alive, does not consider it to be living in itself or eternal. The soul, however, is the contingent breath, by which lightweight bodies (air) are inhaled and exhaled. It is an integral part of a living human being such as his flesh, blood or body structures.
Burial Process of a Seismic Station by Moving Dunes in Tarim Basin
Authors: Liang Xiaofeng , Zuo Sicheng , Li Shilin , Feng Yongge 
Published: June 2020

AbstractA temporary seismometer vault was buried by a moving sand dune in the Taklimakan Desert at northwestern China in October 2019. The dune gradually covered the solar panel and the power supply to the seismic station was subsequently cut off. Here, we show that the burial process can be diagnosed according to the temperature record from the thermometer in the data-logger, an ultra-low-frequency seismic signal, and the change of high-frequency noise level from the continuous seismograms recorded by the broadband seismometer. The ultra-low-frequency seismic signal reflects the thermoelastic effect of the suspension spring in the seismometer corresponding to the temperature gradient in the sensor vault. At the same time, the variation of high-frequency noise level correlates well with the temperature profile and the ultra-low-frequency seismic signal, indicating the ground wind intensity. The peak frequency shifts and their different responses on three-component waveforms for the high-frequency noise might reflect the distance from the moving dunes to the station and their moving directions. This observation shows a potential usage of continuous seismograms to study rapid environment change around a temporary seismic station.
Bezpieczeństwo społeczne i ekonomiczne jako elementy polityki gospodarczej państwa i ryzyka
Authors: Łuczyszyn Tomasz , Łuczyszyn Andrzej 
Published: June 2020

Kategorie bezpieczeństwa społecznego i ekonomicznego zaliczane są we współczesnych realiach (społeczno-gospodarczo-politycznych) do jednych z najistotniejszych czynników rozwoju. Oczywiste jest, że każdy rozwój niesie za sobą podniesienie jakości życia mieszkańców. Przez podniesienie jakości życia rozumie się przede wszystkim istotną poprawę stanu poczucia bezpieczeństwa wśród obywateli, życie w czystym, zdrowym i sprzyjającym środowisku przyrodniczym, uczestnictwo w kulturze, przy-należność do zintegrowanej wspólnoty lokalnej umożliwiającej lepszą harmonizację życia codziennego i zawodowego czy możliwość realizacji poglądów w społeczeństwie obywatelskim. Oznacza to, że polityka państwa zmierzająca do szybkiego i stabilnego rozwoju musi uwzględniać bezpieczeństwo w systemie działania gospodarki narodowej.
Motywacja zawodowa funkcjonariuszy rozpoczynających pracę w więziennictwie
Authors: Poklek Robert 
Published: June 2020

Służba Więzienna jest grupą dyspozycyjną, a sam zawód funkcjonariusza więziennego obarczony wieloma trudnościami wynikającymi ze specyfiki środowiska instytucji totalnej, zagrożeń ze strony więźniów oraz niezbyt wysokim prestiżem i szacunkiem społeczeństwa. Nasuwa się pytanie, jakimi motywami kierują się osoby podejmujące decyzję o wstąpieniu do służby i zawodowe związanie się z więziennictwem. W opracowaniu zaprezentowano badania własne z zakresu struktury motywacji zawodowej przeprowadzone wśród nowo przyjętych funkcjonariuszy w latach 2012 oraz 2017. Oprócz analizy natężenia kierunków motywacji dokonano porównań pomiędzy grupami funkcjonariuszy przyjętych w roku 2012 i 2017, biorąc pod uwagę przemiany społeczno-ekonomiczne zaistniałe w cią-gu pięciu lat, a zwłaszcza zmiany ustawy emerytalnej funkcjonariuszy służb mundurowych.