bluuebunny/crossref_metadata_2025_split huggingface dataset:
Truncated T parasite staircase fractal U‐slot antenna for multiple advance internet of things applications
Authors: Goswami Pankaj K. , Goswami Garima 
Published: October 2019

AbstractThe internet of things (IoT) connects billions of smart heterogeneous modules in long‐term evolution (LTE) and LTE‐advance. The rapid growth of IoT has attracted typical wireless sensors designs for machine‐to‐machine communication. More action is required to improve quality, bandwidth, interfacing compatibility and efficiencies of such smart systems. This article presents an antenna design evolution to enhance compatibility, impedance matching and high bandwidth fidelity to smart wireless IoT sensors. A compact 12 × 18 × 1.6 mm3 staircase‐fractal slot antenna with truncated “T” parasites, gives promising characteristics for IoT applications in UWB and GSM/GPS range. Antenna is modeled and simulated on high frequency structure simulator. The prototype is fabricated and experimented to validate practical feasibility of antenna for wireless sensor based applications. The antenna resonates on 2.4, 5, and 9.55 GHz, exhibits complete UWB (3.1‐10.5 GHz). Additionally, offers GPS/GSM compatibility for real time applications. Therefore, the proposed antenna has novel utility of compatibility enhancement among multiple wireless sensors interface embedded in advance IoT based application.
A noise correction of the γ‐index method for Monte Carlo dose distribution comparison
Authors: Cohilis Marie , Sterpin Edmond , Lee John A. , Souris Kevin 
Published: October 2019

PurposeDue to the increasing complexity of IMRT/IMPT treatments, quality assurance (QA) is essential to verify the quality of the dose distribution actually delivered. In this context, Monte Carlo (MC) simulations are more and more often used to verify the accuracy of the treatment planning system (TPS). The most common method of dose comparison is the γ‐test, which combines dose difference and distance‐to‐agreement (DTA) criteria. However, this method is known to be dependent on the noise level in dose distributions. We propose here a method to correct the bias of the γ passing rate (GPR) induced by MC noise.MethodsThe GPR amplitude was studied as a function of the MC noise level. A model of this noise effect was mathematically derived. This model was then used to predict the time‐consuming low‐noise GPR by fitting multiple fast MC dose calculations. MC dose maps with a noise level between 2% and 20% were computed, and the GPR was predicted at a noise level of 0.3%. Due to the asymmetry of the γ‐test, two different cases were considered: the MC dose was first set as reference dose, then as evaluated dose in the γ‐test. Our method was applied on six proton therapy plans including analytical doses from the TPS or patient‐specific QA measurements.ResultsAn average absolute error of 4.31% was observed on the GPR computed for MC doses with 2% statistical noise. Our method was able to improve the accuracy of the gamma passing rate by up to 13%. The method was found especially efficient to correct the noise bias when the DTA criterion is low.ConclusionsWe propose a method to enhance the γ‐evaluation of a treatment plan when there is noise in one of the compared distributions. The method allows, in a tractable time, to detect the cases for which a correction is necessary and can improve the accuracy of the resulting passing rates.
NMR spectral analysis of strongly second‐order 6‐, 8‐, 9‐ and 10‐ spin‐systems (1H─19F, 19F─19F, and 13C─19F) in perfluorotoluyl‐ and tetrafluoro‐pyridyl‐aromatics using the lineshape method ANATOLIA
Authors: Edgar Mark , Hayward Dee , Zeinali Fatemeh , Riaz Shahzad , Weaver George W. 
Published: October 2019

AbstractA simple to use nuclear magnetic resonance analysis method has been tested on complex 1H, 19F, and 13C multiplets. This open‐source line‐shape analysis method analysis of total lineshape (ANATOLIA)1 provides some significant advantages over traditional assign‐iterate methods of NMR spectral analysis by avoiding false minima and progressing optimisation to the global minimum. The target molecules are 1‐perfluorotol‐4‐yl‐2‐perfluorotol‐4‐yl‐oxymethyl‐1H‐benzimidazole (molecule‐I) and 1‐tetrafluoropyrid‐4‐yl‐2‐tetrafluoropyrid‐4‐yl‐thio‐1H‐benzimidazole (molecule‐II) which were produced as part of a family of fluorinated drug scaffolds prepared for anticancer and antiparasitic screening. Spectra display significant second‐order effects with 1H Δδ = 3.68 and 4.67 Hz for the aromatic hydrogen “triplets”, with 19F 4JAA', 4JBB', 4JXX', and 4JYY' coupling constants range from +4.8 to −14.0 Hz and for 13C‐isotopomers 19F Δδ of up to 111.56 Hz. A spin‐system of six coupling nuclei (HaHbHcHd FYFY') was analysed in 12 s, a spin‐system of nine coupling fluorine nuclei (AA'BB'CCC‐YY') was analysed within 2 min, and 10 coupling nuclei (XX'YY'ZZZ‐BB'‐Hd) was optimised in 6 min using a laptop computer. ANATOLIA was also robust enough to be able to yield accurate spectral values from inaccurate input values. In both compounds, a fluorine–fluorine coupling constant was identified between the two fluoro‐aromatic rings (FBB' and FYY') of +4.05 and +4.67 Hz and attributed to a through‐space interaction. Ab initio structure optimisations and coupling constant calculations provided useful input data for spectral analysis. A modern 19F nuclear magnetic resonance spectrum of perfluorotoluene (octafluorotoluene) and analysis from 1975 was used as a test data set to assess ANATOLIA.
Prediction model of postnatal renal function in fetuses with lower urinary tract obstruction (LUTO)—Development and internal validation
Authors: Duin Leonie K. , Fontanella Federica , Groen Henk , Adama van Scheltema Phebe N. , Cohen‐Overbeek Titia E. , Pajkrt Eva , Bekker Mireille , Willekes Christine , Bax Caroline J. , Oepkes Dick , Bilardo Caterina M. 
Published: October 2019

AbstractObjectiveTo develop a prediction model of postnatal renal function in fetuses with lower urinary tract obstruction (LUTO) based on fetal ultrasound parameters and amniotic fluid volume.MethodsRetrospective nationwide cohort study of fetuses with postnatally confirmed LUTO and known eGFR. Fetuses treated with fetal interventions such as vesico‐amniotic shunting or cystoscopy were excluded. Logistic regression analysis was used to identify prognostic ultrasound variables with respect to renal outcome following multiple imputation of missing data. On the basis of these fetal renal parameters and amniotic fluid volume, a model was developed to predict postnatal renal function in fetuses with LUTO. The main study outcome was an eGFR less than 60 mL/min * 1.73 m2 based on the creatinine nadir during the first year following diagnosis. Model performance was evaluated by receiver operator characteristic (ROC) curve analysis, calibration plots, and bootstrapping.ResultsHundred one fetuses with a confirmed diagnosis of LUTO were included, eGFR less than 60 was observed in 40 (39.6%) of them. Variables predicting an eGFR less than 60 mL/min * 1.73m2 included the following sonographic parameters: hyperechogenicity of the renal cortex and abnormal amniotic fluid volume. The model showed fair discrimination, with an area under the ROC curve of 0.70 (95% confidence interval, 0.59‐0.81, 0.66 after bootstrapping) and was overall well‐calibrated.ConclusionThis study shows that a prediction model incorporating ultrasound parameters such as cortical appearance and abnormal amniotic fluid volume can fairly discriminate an eGFR above or below 60 mL/min * 1.73m2. This clinical information can be used in identifying fetuses eligible for prenatal interventions and improve counseling of parents.
Impact of early diagnosis and noninvasive prenatal testing (NIPT): Knowledge, attitudes, and experiences of parents of children with sex chromosome aneuploidies (SCAs)
Authors: Samango‐Sprouse Carole A. , Porter Grace F. , Lasutschinkow Patricia C. , Tran Selena L. , Sadeghin Teresa , Gropman Andrea L. 
Published: October 2019

AbstractObjectiveTo investigate the attitudes of parents of children with a sex chromosome aneuploidy (SCA) regarding the impact of an early diagnosis and noninvasive prenatal testing (NIPT).MethodA survey consisting of multiple choice and long response formatted questions was completed by parents of children with SCA(s).ResultsFifty‐five participants responded to the survey. A total of 88.1% of participants who received an early diagnosis expressed that it had a positive impact on their child's life. Of the 23 participants who utilized NIPT, 95.7% believed it was a decisive factor in their life because they could research the disorders prior to the birth of their child (35.3%), pinpoint valuable resources and interventions (38.2%), and determine possible risk factors of neurodevelopmental delays to be considered after delivery (20.6%).ConclusionThis study documented parental perspectives on the impact of an early SCA diagnosis and attitudes towards NIPT use for identifying those at risk for SCAs. These informative and insightful results provide personal experiences that health care providers may want to consider when providing prenatal counseling on NIPT for expectant mothers. As this analysis is the first of its kind, ascertainment is limited, and future research should aim to expand these findings by investigating the different factors influencing attitudes towards NIPT.
Natal origin of the invasive biosecurity pest, brown marmorated stink bug (Halyomorpha halys: Penatomidae), determined by dual‐element stable isotope‐ratio mass spectrometry
Authors: Holder Peter W , Van Hale Robert J , Frew Russell , George Sherly , Armstrong Karen F 
Published: October 2019

AbstractBACKGROUNDPost‐border detection of a single brown marmorated stink bug (BMSB) in New Zealand warranted a biosecurity response, the nature of which would be influenced by its status as part of an established population or as a new arrival. Stable isotope analysis has the potential to determine natal origins, but is difficult to achieve for samples as small as a single insect. Here an analytical modification to measure small samples was successfully trialled as a means to supply evidence as to the local or exotic natal origin of the intercepted BMSB specimen.RESULTSSufficient analytical sensitivity was achieved using a modified isotope ratio mass spectrometry method, involving thermolysis and carbon monoxide cryofocusing, to enable the simultaneous analysis of δ2H and δ18O from wings of the post‐border BMSB sample. The values were much lower than those of the New Zealand green vegetable bug, used as a local reference. However, they fell within the range of those for BMSB of Northern Hemisphere origin intercepted at the New Zealand border over the same time period, specifically overlapping with the USA and Italy, but not China.CONCLUSIONThe isotope signature of the post‐border detected BMSB suggested a significantly cooler climate than the North Island of New Zealand, indicating that it was a new arrival and did not represent an established population. © 2019 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Disturbance‐prediction–based control of input time delay systems for rejection of unknown frequency disturbances
Authors: Wen Xinyu , Yan Peng 
Published: October 2019

SummaryIn this paper, a novel disturbance rejection approach is presented for a class of input time‐delay systems subject to sinusoidal disturbances with unknown frequency. In particular, an auxiliary observer is proposed to represent the periodic disturbance in a parametric uncertainty form, where the unknown factor related to disturbance frequency can be estimated. Furthermore, the correlation between the future disturbance and the auxiliary observer output is analyzed, such that the future disturbances can be predicted and rejected through the input channel. Based on the aforementioned observer and predictor structure, the overall control architecture can be established as a framework of disturbance‐prediction–based control for systems with input time delays, where the conditions on the asymptotic stability of the closed‐loop systems are also derived. Finally, numerical examples are provided to illustrate the effectiveness of the proposed control approach.
Programmable DNA Nanoindicator‐Based Platform for Large‐Scale Square Root Logic Biocomputing
Authors: Zhou Chunyang , Geng Hongmei , Wang Pengfei , Guo Chunlei 
Published: October 2019

AbstractThe prospect of programming molecular computing systems to realize complex autonomous tasks has advanced the design of synthetic biochemical logic circuits. One way to implement digital and analog integrated circuits is to use noncovalent hybridization and strand displacement reactions in cell‐free and enzyme‐free nucleic acid systems. To date, DNA‐based circuits involving tens of logic gates capable of implementing basic and complex logic functions have been demonstrated experimentally. However, most of these circuits are still incapable of realizing complex mathematical operations, such as square root logic operations, which can only be carried out with 4 bit binary numbers. A high‐capacity DNA biocomputing system is demonstrated through the development of a 10 bit square root logic circuit. It can calculate the square root of a 10 bit binary number (within the decimal integer 900) by designing DNA sequences and programming DNA strand displacement reactions. The input signals are optimized through the output feedback to improve performance in more complex logical operations. This study provides a more universal approach for applications in biotechnology and bioengineering.
Acute exposure to nocturnal train noise induces endothelial dysfunction and pro-thromboinflammatory changes of the plasma proteome in healthy subjects
Authors: Herzog Johannes , Schmidt Frank P. , Hahad Omar , Mahmoudpour Seyed Hamidreza , Mangold Alina K. , Garcia Andreo Pascal , Prochaska Jürgen , Koeck Thomas , Wild Philipp S. , Sørensen Mette , Daiber Andreas , Münzel Thomas 
Published: October 2019

Abstract
Nocturnal train noise exposure has been associated with hypertension and myocardial infarction. It remains unclear whether acute nighttime train exposure may induce subclinical atherosclerosis, such as endothelial dysfunction and other functional and/or biochemical changes. Thus, we aimed to expose healthy subjects to nocturnal train noise and to assess endothelial function, changes in plasma protein levels and clinical parameters. In a randomized crossover study, we exposed 70 healthy volunteers to either background or two different simulated train noise scenarios in their homes during three nights. After each night, participants visited the study center for measurement of vascular function and assessment of other biomedical and biochemical parameters. The three nighttime noise scenarios were exposure to either background noise (control), 30 or 60 train noise events (Noise30 or Noise60), with average sound pressure levels of 33, 52 and 54 dB(A), respectively. Flow-mediated dilation (FMD) of the brachial artery was 11.23 ± 4.68% for control, compared to 8.71 ± 3.83% for Noise30 and 8.47 ± 3.73% for Noise60 (p < 0.001 vs. control). Sleep quality was impaired after both Noise30 and Noise60 nights (p < 0.001 vs. control). Targeted proteomic analysis showed substantial changes of plasma proteins after the Noise60 night, mainly centered on redox, pro-thrombotic and proinflammatory pathways. Exposure to simulated nocturnal train noise impaired endothelial function. The proteomic changes point toward a proinflammatory and pro-thrombotic phenotype in response to nocturnal train noise and provide a molecular basis to explain the increased cardiovascular risk observed in epidemiological noise studies.
Tunable viscosity modification with diluted particles: when particles decrease the viscosity of complex fluids
Authors: Gvaramia Manuchar , Mangiapia Gaetano , Pipich Vitaliy , Appavou Marie-Sousai , Jaksch Sebastian , Holderer Olaf , Rukhadze Marina D. , Frielinghaus Henrich 
Published: October 2019

Abstract
While spherical particles are the most studied viscosity modifiers, they are well known only to increase viscosities, in particular at low concentrations of approx. 1%. Extended studies and theories on non-spherical particles in simple fluids find a more complicated behavior, but still a steady increase with increasing concentration. Involving platelets in combination with complex fluids—in our case, a bicontinuous microemulsion—displays an even more complex scenario that we analyze experimentally and theoretically as a function of platelet diameter using small angle neutron scattering, rheology, and the theory of the lubrication effect, to find the underlying concepts. The clay particles effectively form membranes in the medium that itself may have lamellar aligned domains and surfactant films in the case of the microemulsion. The two-stage structure of clay and surfactant membranes explains the findings using the theory of the lubrication effect. This confirms that layered domain structures serve for lowest viscosities. Starting from these findings and transferring the condition for low viscosities to other complex fluids, namely crude oils, even lowered viscosities with respect to the pure crude oil were observed. This strengthens our belief that also here layered domains are formed as well. This apparent contradiction of a viscosity reduction by solid particles could lead to a wider range of applications where low viscosities are desired. The same concepts of two-stage layered structures also explain the observed conditions for extremely enhanced viscosities at particle concentrations of 1% that may be interesting for the food industry.
Childhood Behavioural Problems and Adverse Outcomes in Early Adulthood: a Comparison of Brazilian and British Birth Cohorts
Authors: Hammerton Gemma , Murray Joseph , Maughan Barbara , Barros Fernando C. , Gonçalves Helen , Menezes Ana Maria B. , Wehrmeister Fernando C. , Hickman Matthew , Heron Jon 
Published: October 2019

AbstractPurposeExamine associations between childhood behavioural problems with criminal behaviour, emotional disorders, substance use and unemployment in early adulthood in two birth cohorts from a middle- and high-income country.MethodsData were utilised from large, prospective birth cohorts in Brazil (1993 Pelotas Birth Cohort;N = 3939) and the UK (Avon Longitudinal Study of Parents and Children; ALSPAC;N = 5079). Behavioural problems were reported on by parents at age 11 years (including disobeys, temper, lies, fights, steals). Outcomes (assessed with youth between ages 22 and 24 years) included criminal behaviour, emotional disorders, substance use and NEET (not in education, employment or training).ResultsIn both cohorts, children with ‘conduct problems’ (those with increased probability of all five behaviours at age 11), were at higher risk of criminal behaviour, emotional disorders and NEET in adulthood compared to those with ‘low problems’. Associations for ‘conduct problems’ were stronger in Pelotas compared to ALSPAC for hazardous alcohol use [Pelotas: risk ratio = 1.39, 95% CI = 1.14–1.70; ALSPAC: risk ratio = 0.76, 95% CI = 0.57–1.02] and illegal drug use [Pelotas: risk ratio = 1.32, 95% CI = 1.16–1.50; ALSPAC: risk ratio = 1.05, 95% CI = 0.91–1.20], whereas associations for criminal behaviour [Pelotas: risk ratio = 1.92, 95% CI = 1.29–2.86; ALSPAC: risk ratio = 2.75, 95% CI = 2.04–3.73] and NEET [Pelotas: risk ratio = 1.38, 95% CI = 1.13–1.70; ALSPAC: risk ratio = 3.04, 95% CI = 1.99–4.65] were stronger in ALSPAC.ConclusionsChildhood conduct problems were associated with criminal behaviour, emotional disorders and unemployment in adulthood in both Brazil and the UK. Additional associations were found for substance use in Brazil.
Evaluating the effect of gentamicin-clindamycin lavage on post-operational pain and infection through laparoscopic colectomy surgery
Authors: Negahi Alireza , Arminfar Amirhossein , Vaseghi Hamed , Moradi Mohammad , Alemrajabi Mahdi 
Published: October 2019

Abstract
Introduction Peritoneal antibiotic or normal saline lavage is seen to be beneficial in order to reduce the pain or infection risk through laparoscopic surgeries. It can also be applied for laparoscopic colectomy surgeries. In this study, we have compared the effects of antibiotic solution lavage (gentamycin-clindamycin) with normal saline lavage in patients undergoing laparoscopic colectomy surgery.
Method In this double-blind Randomized Controlled Trial (RCT), 40 patients undergoing laparoscopic colectomy surgery were divided into antibiotic and normal saline lavage groups (20 patients in each group). Post-operational pain, need for painkiller, white blood cells count, C-reactive protein level, duration of hospitalization and wound infection were compared in 30 days between the groups.
Results Antibiotic lavage group had significantly less pain than the normal saline group (p
< 0.05) through 3, 6, 12 and 24
h after surgery. C-reactive protein level, white blood cells count, painkiller use, and hospitalization duration were significantly lower in antibiotic group. However, there was no difference regarding wound or intra-abdominal infection between the both groups.
Conclusion Using gentamicin-clindamycin peritonea lavage helps patients undergoing laparoscopic colectomy surgery in pain reduction, need for painkillers and hospitalization duration.
Sources for Altitude Illness Information for Trekkers in the Himalayas
Authors: Strickland Brian M. , Kanaan Nicholas C. 
Published: October 2019

Introduction Educational materials are important tools in the prevention of altitude illness among individuals traveling to high altitude destinations. Travelers obtain information about altitude illness from many different educational resources. Our objective was to determine which educational resources for altitude illness prevention were used by trekkers on the Everest Base Camp trek and Annapurna Circuit. We also sought to compare which resources were used by individuals from different geographic areas. Methods A survey was administered to trekkers attending an altitude illness information lecture at the Himalayan Rescue Association clinic. Trekkers provided their basic demographic information and educational resources they used while preparing for the trek. Comparisons were made between trekkers based on the resources they used, as well as their age and country of origin. Results Of 1075 surveys administered, 906 were completed. Internet sources were most commonly used by trekkers (49%), followed by friends or family (22%), and healthcare providers (18%). The age of participants using Internet sources was 36 ± 12 y (mean ± SD), lower than those who did not use Internet sources (39 ± 14 y, P < 0.01). Participants came from 8 geographic areas; Europe (55%), North America (24%), and Oceania (11%) made up the vast majority. Compared to the overall cohort, participants from Oceania demonstrated more Internet reliance at 65% (χ2(1, n = 102)=9.7, P < 0.01). Conclusions In this group of trekkers in the Himalayas, the Internet was the most common source of information on altitude illness prevention and management. Trekkers using Internet sources were slightly younger than non-Internet users.