bluuebunny/crossref_metadata_2025_split huggingface dataset:
The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality
Authors: Issaian Aaron , Hay Ariel , Dzieciatkowska Monika , Roberti Domenico , Perrotta Silverio , Darula Zsuzsanna , Redzic Jasmina , Busch Micheal P. , Page Grier P. , Hansen Kirk C. , Eisenmesser Elan Z , Zimring James C , D’Alessandro Angelo 
Published: December 2020

AbstractBand 3 (anion exchanger 1 - AE1) is the most abundant membrane protein in red blood cells (RBCs), the most abundant cell in the human body. A compelling model, based on indirect evidence, posits that - at high oxygen saturation - the N-term cytosolic domain of AE1 binds to and inhibits glycolytic enzymes, thus diverting metabolic fluxes to the pentose phosphate pathway to generate reducing equivalents. Dysfunction of this mechanism occurs during RBC aging or storage under blood bank conditions, suggesting a role for AE1 in the regulation of blood storage quality and efficacy of transfusion – a life-saving intervention for millions of recipients worldwide. Here we leverage two murine models carrying genetic ablations of AE1 to provide the first direct mechanistic evidence of its role in metabolic regulation and blood storage quality. Observations in mice phenocopied those in a human subject lacking expression of AE11-11(band 3Neapolis),while common polymorphisms in the region coding for AE11-56increased susceptibility to osmotic hemolysis in healthy blood donors. Through thermal proteome profiling and cross-linking proteomics, we provide the first comprehensive analysis of the RBC interactome, with a focus on AE11-56and validate recombinant AE1 interactions with glyceraldehyde 3-phosphate dehydrogenase (GAPDH). Finally, we show that incubation with a cell-penetrating AE11-56peptide can rescue the metabolic defect in glutathione recycling and boost post-transfusion recoveries of stored RBCs from healthy human donors and genetically ablated mice, paving the way for the in vivo metabolic manipulation of RBCs facing oxidant stress – a landmark of many diseases.Key pointsGenetic ablation of N-term of band 3 results in significant metabolic aberrations and poor post-transfusion recoveries in mice and humans;Structural studies on the N-term of band 3 reveal a complex interactome with several enzymes, including GAPDH;
Teaching, virtually: a critical reflection
Authors: Powell Lisa , McGuigan Nicholas 
Published: December 2020

Purpose
The purpose of this paper is to present critical educator reflections on the pivot from the traditional physical accounting classroom to the virtual learning environment amidst COVID-19 pandemic lockdowns.

Design/methodology/approach
This paper outlines the reflexive experiences of two accounting educators on their scholarly journey into virtual learning and their inhabiting of the virtual accounting classroom. We adopt a critical stance in exploring what has been lost and insights gained.

Findings
We heed caution in the ongoing reliance on digital technologies and virtual learning that strip accounting education of its richness and complexity. Although the virtual learning environment brings with it benefits of accessibility and flexibility, it fails to replace the complexity of human connection, authenticity and informal spontaneity found in face-to-face learning. We further contend that COVID-19 presents an opportunity to rethink accounting education. We encourage educators to embrace this opportunity as a force for educational transformation; to reimagine an accounting education that embraces change, ambiguity and humanistic qualities such as empathy, compassion and humility.

Originality/value
Our critical educator reflections explore the impact of COVID-19 on the humanistic qualities at the heart of education and on the future of accounting education. This paper contributes to the scholarship of teaching and learning during global pandemics and other crises.
Achieving food security through live animal imports in the Gulf Cooperation Council countries
Authors: Gani Azmat 
Published: December 2020

PurposeThis article examines the main factors that drive live animal imports in the Gulf Cooperation Council (GCC) countries in the Middle East.Design/methodology/approachThe analysis is based on a gravity model framework, and it incorporates annual data for imports of cattle, sheep and goats during the period 2004–2017 for six countries. The panel estimation technique is employed to disentangle the drivers of the GCC live animal imports.FindingsThe results reveal that imports of live animals are consistently positive and statistically significantly correlated with the economic sizes of importer countries, liner shipping connectivity (LSC) (for cattle and goats) and culture (for cattle and sheep). Other determinants include falling tariffs for live cattle imports and falling costs of doing business for live sheep imports. Distance is found to exert statistically significant friction for imports of live goats.Practical implicationsThe GCC countries offer substantial opportunities for livestock trade to fulfil the growing demand for meat as a dietary requirement. Countries aiming at the GCC live animal segment of agricultural business would have to ensure reliable access to maritime transport connectivity and better understanding and insights into the business environment, transport logistics, trade policies, economic strength and cultural connections with meat consumption. The food-related supply chain system ought to have an extensive awareness of variables as the findings of this study revealed that can impact exchanges encountered across the supply chains.Originality/valueUntil now, no study has empirically investigated the effect of live animal imports within a coherent trade theoretical framework in the GCC. The novelty of this research is that it makes the first attempt to identify the factors driving the extensive GCC live animal imports for meat consumption with a specific geographical focus. This study also complements the existing sparse empirical literature on trade-in live animals.
The impact of temporary workers on the conversion of innovation efforts into product innovations: the case of Spanish companies
Authors: Rodríguez-Ruiz Óscar , Fernández-Menéndez José , Díaz-Martínez Zuleyka , Fossas-Olalla Marta 
Published: December 2020

PurposeIn this paper, we study the influence of temporary workers in the relationship between innovation effort and product innovation in a large sample of Spanish manufacturing firms in a six-year period.Design/methodology/approachThe article uses a zero-inflated regression model to analyse how the performance of innovation efforts is affected by the impact of temporary employment.FindingsOur results show that the use of temporary employment has adverse effects for the conversion of innovation investments into innovation outputs. Firms with higher levels of fixed-term workers have less product innovations in comparison to firms that do not use this kind of workforce. However, this negative impact is less detrimental in technological-intensive sectors.Originality/valueThe value of this research for employment relations is salient as workers long-term protection seems to enhance the effectiveness of the innovation process. At the same time, the effects of temporary work vary depending on the sector.
The “stay at home” orders effect on mental health of Egyptian adults during the COVID-19 pandemic partial lockdown
Authors: Saleh Mai Sabry 
Published: December 2020

Purpose
Mental health is one of the aspects seriously affected by the COVID-19 pandemic. Governmental preventive measures worldwide disturbed people’s daily routine, social activities, access to education and even impacted their working environment. The present work aims at screening the expected negative effects on mental and psychological wellbeing.

Design/methodology/approach
An online survey was introduced through an internet-based platform to assess mental wellbeing (MW) and stress among Egyptian adults using SHORT Warwick-Edinburgh Mental Wellbeing Scale and Falsification of Type Scale, respectively. Socio-demographics were also collected. Data from 150 respondents through the period from May 25 till June 1 were tabulated and statistical analyses were performed.

Findings
More than 70% of respondents declared jobs being affected by the pandemic. Females showed deteriorated state of mental health, together with the youth (≤44 years) and those who lost their jobs or suffered reduced income. In conclusion, mental health as expressed by MW and stress showed to be affected among the Egyptian adults due to the “stay at home” orders. Prompt actions are highly recommended to save vulnerable populations at the time being and from the aggravation of their mental problems in the long term.

Originality/value
The study is the first in Egypt figuring out affected populations and vulnerable categories that need extra care in the future. It provides valuable data and expresses reasonable explanations to the obtained findings. The study also introduces recommendations and highlights hot topics for future research.
Data dissemination for green-VANETs communication: an opportunistic optimization approach
Authors: D. Chandramohan , Dumka Ankur , V. Dhilipkumar , Loganathan Jayakumar 
Published: December 2020

Purpose
This paper aims to predict the traffic and helps to find a solution. Unpredictable traffic leads more vehicles on the road. The result of which is one of the factors that aggravate traffic congestion. Traffic congestion occurs when the available transport resources are less when compared to the number of vehicles that share the resource. As the number of vehicles increases the resources become scarce and congestion is more.

Design/methodology/approach
The population of the urban areas keeps increasing as the people move toward the cities in search of jobs and a better lifestyle. This leads to an increase in the number of vehicles on the road. However, the transport network, which is accessible to the citizens is less when compared to their demand.

Findings
The demand for resources is higher than the actual capacity of the roads and the streets. There are some circumstances, which will aggravate traffic congestion. The circumstances can be the road condition (pot holes and road repair), accidents and some natural calamities.

Originality/value
There is a lot of research being done to predict the traffic and model it to find a solution, which will make the condition better. However, still, it is an open issue. The accuracy of the predictions done is less.
Market microstructure: a comparative study of Bombay stock exchange and national stock exchange
Authors: Goel Anshi , Tripathi Vanita , Agarwal Megha 
Published: December 2020

PurposeThe present study seeks to investigate the relative edge between the market microstructure of the two leading stock exchanges of the Indian capital market, that is BSE and NSE with a focus on analysing their trading mechanism, efficiency, liquidity and volatility.Design/methodology/approachWe analyse the microstructure of BSE and NSE on the basis of: (1) trading mechanism – ownership structure, listing of securities, trading system and settlement and clearing process; (2) information efficiency using unit root test, serial correlation, runs test, variance ratio and the ARIMA model; (3) liquidity using trading statistics no. of listed Companies, market capitalisation, no. of trades etc. and (4) volatility using standard deviation and GARCH(1,1) model.FindingsA comprehensive scrutiny on microstructure of BSE and NSE makes it evident that the two leading stock exchanges of India are mostly similar and leave no scope to choose between them. Both the exchanges are demutualised corporate entities with a fully automated trading system in an order-driven market, informationally inefficient as evidenced by the predictability of returns, have shown tremendously growing trading statistics and by and large a declining trend in volatility over the years.Practical implicationsUnderstanding the components of the microstructure black-box will provide the regulatory bodies with an intellectual framework to strengthen the market architecture. Both the exchanges will get aware of the dynamics of trading, can grow to be more competitive and attract more firms for listing and investors for trading of securities. Also, investors, portfolio managers and equity analysts will be able to make better investment strategies by understanding how the market works.Originality/valueResearch in the area of market microstructure has been severely neglected, especially in the context of the Indian market. India is the world's fastest growing economies and we have witnessed tremendous reforms in the capital market. The past two and a half decades have brought about several innovations via demutualisation, screen-based trading, emergence of clearing corporations, innovative financial products and intense use of IT in the Indian stock market. A spurt of reforms and the emerging environment make it crucial to deeply analyse the market structure and design of two premier stock exchanges of India – BSE and NSE.
Organizational readiness for artificial intelligence in health care: insights for decision-making and practice
Authors: Alami Hassane , Lehoux Pascale , Denis Jean-Louis , Motulsky Aude , Petitgand Cecile , Savoldelli Mathilde , Rouquet Ronan , Gagnon Marie-Pierre , Roy Denis , Fortin Jean-Paul 
Published: December 2020

PurposeArtificial intelligence (AI) raises many expectations regarding its ability to profoundly transform health care delivery. There is an abundant literature on the technical performance of AI applications in many clinical fields (e.g. radiology, ophthalmology). This article aims to bring forward the importance of studying organizational readiness to integrate AI into health care delivery.Design/methodology/approachThe reflection is based on our experience in digital health technologies, diffusion of innovations and healthcare organizations and systems. It provides insights into why and how organizational readiness should be carefully considered.FindingsAs an important step to ensure successful integration of AI and avoid unnecessary investments and costly failures, better consideration should be given to: (1) Needs and added-value assessment; (2) Workplace readiness: stakeholder acceptance and engagement; (3) Technology-organization alignment assessment and (4) Business plan: financing and investments. In summary, decision-makers and technology promoters should better address the complexity of AI and understand the systemic challenges raised by its implementation in healthcare organizations and systems.Originality/valueFew studies have focused on the organizational issues raised by the integration of AI into clinical routine. The current context is marked by a perplexing gap between the willingness of decision-makers and technology promoters to capitalize on AI applications to improve health care delivery and the reality on the ground, where it is difficult to initiate the changes needed to realize their full benefits while avoiding their negative impacts.
The relation of workplace spirituality with employees’ innovative work behaviour: the mediating role of psychological empowerment
Authors: Bantha Tapas , Nayak Umakanta 
Published: December 2020

PurposeThe purpose of the paper is to examine the relationship between workplace spirituality and employees’ innovative work behaviour and also to check the mediating role of psychological empowerment on this relationship from the lens of self-determination theory (SDT).Design/methodology/approachAn internet-based survey was conducted among knowledge workers, i.e. 340 employees (software engineers and product developers) working in different US-based multi-national companies operating in India. The relationships are tested by using partial least squares structural equation modelling (PLS-SEM) and, for mediation, Preacher and Hayes (2008) procedure has been used.FindingsThe PLS-SEM and Preacher and Hayes (2008) mediation results revealed that there is a significant positive relationship between workplace spirituality and employees’ innovative work behaviour. There is also a substantial effect of workplace spirituality on psychological empowerment and psychological empowerment on employees’ innovative work behaviour. Psychological empowerment is found to be mediating fully between workplace spirituality and employees’ innovative work behaviour.Practical implicationsIn the context of organizations, it will be really beneficial to enhance employees’ innovative work behaviour through inculcating workplace spirituality. Promoting workplace spirituality is one of the prerequisites in organizations towards creating sustainability and establishing an empowered organization in this competitive business environment.Originality/valueThere is a dearth of studies in linking the relationship between workplace spirituality and employees’ innovative work behaviour with the mediating role of psychological empowerment from the lens of SDT.
Knowledge and use of accounting software: evidence from Oman
Authors: Thottoli Mohammed Muneerali 
Published: December 2020

PurposeThe aim of this paper is to determine the influence of knowledge and use of accounting software among small and medium entrepreneurs (SMEs) in Oman.Design/methodology/approachThis study has used qualitative approach. Further, the paper elucidated the significance of knowledge of accounting software and evaluated the relationship between knowledge and its adoption or use of accounting software among SMEs in Oman. Purposive sampling method was used to choose the target interviewees required for the survey (semi-structured interview). This method has been applied by selected accountants who work in SMEs in Oman. Based on practical experience and basic knowledge in the field of accounting, a total of six members are selected as the sample size for the study.FindingsThe findings revealed that the knowledge of accounting software has a significant effect on the use of accounting software, meaning that there is significant and positive relationship among the knowledge of generalized accounting software and the use of such generalized or customized accounting software by SMEs in Oman. In addition, this research shows the empirical evidence of knowledge of accounting software effects on the adoption or use of accounting software among SMEs in OmanPractical implicationsThe study has brought about a new discussion on the importance of information communication technology (ICT) knowledge and use or adoption of accounting software by SMEs for accounting literature. Further, this study emphasizes the usage and benefits of accounting software by accountants in various SMEs. Further, it would be useful to suggest that SMEs and such other types of organizations adopt customized or generalized accounting software that will enhance the practice among accounting professionals.Originality/valueThis paper contributes both theoretical and practical knowledge of accounting in accountants using generalized or customized accounting software and its relationship with accountant in various SMEs or such other organizations; it is an approach that is not widely discussed in the previous studies. Besides, conducting such study in the field of SMEs gives novelty in the literature between SMEs and developing economies. This has discussed the weakness of accountant in implementing accounting software in the organization.
Some antecedent factors that shape SMEs adoption of social media marketing applications: a hybrid approach
Authors: Eze Sunday C. , Chinedu-Eze Vera C. , Bello Adenike O. 
Published: December 2020

Purpose
Although several researchers have made significant efforts to examine the adoption of social media marketing technology in Nigeria, many have focussed on large organizations while others have constantly extrapolated the findings obtained in the Western world as if small and medium enterprises (SMEs) have the same structure, managerial capabilities, and operate in the same way. This has hindered the development of an integrated framework aimed at unravelling the factors shaping the adoption of social media marketing applications in SMEs in Nigeria. The paper, therefore, aims to explore some antecedent factors that shape SMEs adoption of social media marketing applications in SMEs in Nigeria.

Design/methodology/approach
The study deployed a qualitative approach with the use of unstructured and semi-structured interviews with a total of 20 participants drawn purposeful from Nigeria directories and analysed by using a hybrid method of thematic analysis.

Findings
The study developed an extended technology–organization–environment framework (TOE) framework that incorporated the communication context, which aids in identifying 11 key success factors shaping SMEs adoption of social media marketing technology in Nigeria. The findings associated with the extended TOE framework show that they have an impact on social media marketing technology adoption in SMEs.

Research limitations/implications
Because the researchers adopted the qualitative method, the findings may lead to some bias in the analysis of the data which may limit the insights into the key factors shaping the adoption of social media marketing technology adoption. Future studies may adopt a mixed-method approach or a comparative approach to confirm the finding and to better understand the critical factors linked to the framework. Although it is believed the with the use of thematic data analysis, the results are well associated with the structure; however, the structure has limitations. Drawing from the data analysis, the factors are limited. Other factors which may positively influence social media marketing adoption in SMEs. Hence, further studies are needed in this area in a bid to explore these factors by using different research appraoches.

Originality/value
The study has enriched the existing TOE framework and provided insights into the dominant issue faced by SMEs in adopting social media marketing technology, provided an analytical dimension, reliable explanation of these finding and tool for evaluating some of the challenges faced by SMEs in the adoption of social media marketing technology.