bluuebunny/crossref_metadata_2025_split huggingface dataset:
Environmental and spatial effects on coastal stream fishes in the Atlantic rain forest
Authors: Gonçalves Cristina da Silva , Holt Robert Dan , Christman Mary C. , Casatti Lilian 
Published: December 2019

AbstractContemporary and historical factors influence assemblage structure. The environmental and spatial influences acting on fish organization of rain forest coastal streams in the Atlantic rain forest of Brazil were examined. Fish (and functional traits such as morphology, diet, velocity preference, body size), environmental variables (pH, water conductivity, dissolved oxygen, temperature, stream width, flow, depth, substrate), and altitude were measured from 59 stream reaches. Asymmetric eigenvector maps were used to model the spatial structure considering direction of fish movements. Elevation played an important role—fish abundance, biomass, and richness all decrease with increasing elevation. Fish communities are influenced by both environmental and spatial factors, but downstream movements were shown to be more important in explaining the observed spatial variation than were bidirectional and upstream movements. Spatial factors, as well as environmental variables influenced by the spatial structure, explained most of the variation in fish assemblages. The strong spatial structuring is probably attributable to asymmetric dispersal limitation along the altitudinal profile: Dispersal is likely to be more limiting moving upstream than downstream. These fish assemblages reflect scale‐dependent processes: At the stream‐reach scale, fish respond to local environmental filters (habitat structure, water chemistry, and food supply), which are in turn influenced by a larger scale, namely the altitudinal gradient expected in steep coastal mountains. Thus, environmental drivers are not independent of spatial factors, and the effects of local factors can be confounded across the altitudinal gradient. These results may have implications for conservation, because downstream reaches are often neglected in management and conservation plans.Abstract in Portuguese is available with online material.
A case of molecularly confirmed BAP1 inactivated melanocytic tumor with retention of immunohistochemical expression: A confounding factor
Authors: Linos Konstantinos , Atkinson Aaron E. , Yan Shaofeng , Tsongalis Gregory J. , Lefferts Joel A. 
Published: December 2019

AbstractBRCA1‐associated Protein 1 (BAP1)‐inactivated melanocytic nevi/tumors (BIMT) have distinct morphologic features. A typical case exhibits a biphasic population of cytologically bland conventional melanocytes and a second proliferation of larger epithelioid melanocytes with abundant eosinophilic cytoplasm. The vast majority of cases harbor BRAF V600E in both components with bi‐allelic inactivation of BAP1 in the epithelioid component by various molecular mechanisms resulting in loss of nuclear protein expression, which can be demonstrated by immunohistochemistry. We present a case of BIMT with histopathologic features highly suggestive of this entity but unexpected retention of nuclear expression of the BAP1 protein. Subsequent molecular tests showed heterozygous loss of the BAP1 locus on the short arm of chromosome 3 (3p21.1) by chromosomal microarray analysis (CMA) and a suspected c.505C>T p.H169Y pathogenic variant identified by DNA sequencing that was subsequently confirmed by primer‐specific SNaPshot mini‐sequencing. In light of the heterozygous deletion of BAP1, this variant in the remaining allele encodes a catalytically inactive BAP1 mutant protein as shown in functional studies. The presence of a nonfunctional allele within the nucleus combined with a heterozygous deletion of BAP1 explains the clear and characteristic BIMT morphology observed by histopathology. This case underlines the potential importance of molecular diagnostics when protein expression studies do not correlate with morphology.
Attachment of a migrated MitraClip to the left ventricular apex: A novel case report
Authors: Nagai Mirei , Kurokawa Satoshi , Ozaki Makoto , Nomura Minoru 
Published: December 2019

AbstractHerein, we report a novel case of emergency surgical mitral valve replacement for severe mitral valve regurgitation (MR) following MitraClip implantation (Abbott Laboratories, Chicago, IL, USA). Recurrent MR was caused because of the migration of the clip due to the destruction of the mitral valve leaflets with Staphylococcus aureus infective endocarditis. Intra‐operative transesophageal echocardiography revealed that the clip was stuck to the left ventricular apex. Although the device could not be removed surgically, surgical repair of the valve enabled the patient to recover without any further complications.
Social anxiety in young people with first‐episode psychosis: Pilot study of the EMBRACE moderated online social intervention
Authors: McEnery Carla , Lim Michelle H. , Knowles Ann , Rice Simon , Gleeson John , Howell Simmone , Russon Penni , Miles Chris , D'Alfonso Simon , Alvarez‐Jimenez Mario 
Published: December 2019

AbstractAimWe conducted a single‐group pilot study to evaluate the feasibility, acceptability and safety of a novel online intervention (entitled EMBRACE) that includes expert and peer moderation, therapeutic comics and social networking features. The cognitive‐behavioural‐based intervention was specifically designed to treat social anxiety as a primary treatment target in youth with first‐episode psychosis (FEP).MethodsThe 10 participants (17‐26 years; Mage = 23 years) had a diagnosis of FEP and experienced significant levels of social anxiety as defined by exceeding a sub‐threshold clinical score (>30) on the Social Interaction Anxiety Scale (SIAS). They had access to the EMBRACE intervention for 2 months.ResultsIn total, seven out of ten participants completed eight modules or more (total of 12 modules). All participants rated the intervention as positive and safe, and endorsed recommending it to others who experience social anxiety. Improvement in pre‐post social anxiety symptoms, as measured via the SIAS (d = −1.70, P = .0005) and the Liebowitz Social Anxiety Scale (d = −1.35, P = .002) were found. No statistically significant pre‐post improvements were found for depressive or loneliness symptoms.ConclusionEMBRACE was shown to be a feasible, acceptable, and safe online intervention to specifically target social anxiety as a primary treatment concern in young people with FEP.
Innovations in financing: The impact of anchor investors in Indian IPOs
Authors: Bhattacharya Arnab , Chakrabarti Binay Bhushan , Ghosh Chinmoy , Petrova Milena 
Published: December 2019

AbstractIn 2009, the Securities Exchange Board of India allowed qualified institutional investors to anchor initial public offerings (IPOs) by participating in the issue at a price and allocation publicly disclosed preceding the issue. We study anchor investors (AIs) in Indian IPOs during 2009–2017. We find the share allotment and the number of AIs separately have significant impacts on valuation and underpricing; however, the net effect is nonsignificant. Further, AIs significantly influence other institutional investors' participation in the IPO and induce lower aftermarket volatility. Overall, our evidence suggests that AIs boost demand for and mitigate ex ante information uncertainty of IPOs.
Neither core nor periphery: The search for competitive advantage in the automotive semi‐periphery
Authors: Mordue Greig , Sweeney Brendan 
Published: December 2019

AbstractThis article examines a heretofore underexplored category of automotive‐producing nation known as the semi‐periphery. These nations are neither “core” automotive nations whose power derives from hosting headquarters of major automakers, nor are they low‐cost members of the automotive “integrated periphery” like Mexico or countries in Central and Eastern Europe or North Africa. Through a case study of one semi‐periphery country, Canada, the paper assesses automotive semi‐periphery countries' capacity to transition to knowledge‐based activities more typically associated with “core” automotive nations. In so doing, it raises implications for other “semi‐periphery” automotive‐producing nations as well as those currently categorized as “core” or “integrated periphery.”
Case Report: New‐Onset Retinal Migraine After Transseptal Catheterization
Authors: Richmond Lynn , Schneider Ralph P. , Steffel Jan , Sandor Peter S. , Tarnutzer Alexander A. 
Published: December 2019

BackgroundWhile new‐onset migraine headaches and binocular visual aura have been reported after transseptal catheterization (TSC), this case suggests that retinal aura may emerge also after this procedure.Case DescriptionThis 38‐year‐old male with paroxysmal atrial fibrillation had received TSC and cryoablation, and subsequently developed isolated monocular aura phenomena. The first episode happened a few hours after the intervention and was not accompanied by headache or other aura phenomena. The patient’s history was negative for migraine. Brain magnetic resonance imaging demonstrated 2 lacunar diffusion restrictions in the left medial cerebral artery territory that were most likely catheterization related. Over the next 14 days, 3 additional, stereotyped episodes (duration = 20‐30 minutes) with zigzag lines and flickering small bright dots in the central visual field of one eye (moving laterally) occurred. A central scotoma was noted during one episode.ConclusionsThis is the first case with retinal aura phenomena meeting International Classification of Headache Disorders diagnostic criteria for retinal migraine, suggesting that this rare migraine variant can be triggered by TSC.
Synthesis of the ternary metal carbide solid‐solution ceramics by polymer‐derived‐ceramic route
Authors: Liu Honghua , Du Bin , Chu Yanhui 
Published: December 2019

AbstractThe polymer‐derived‐ceramic (PDC) route has been widely used to fabricate the transition‐metal carbides (TMCs). Previously reported works focused mainly on the synthesis of the single or binary TMCs, while the synthesis of the ternary or more component TMCs was rarely reported. Herein, a class of the ternary TMCs, namely (Nb1/3Zr1/3Ta1/3)C solid‐solution ceramics, was successfully synthesized via PDC route for the first time. The as‐synthesized ceramics exhibited the particle‐like morphology with an average particle size of ~250 nm and showed a single rock‐salt crystal structure of metal carbides. At the same time, they had high compositional uniformity from nanoscale to microscale. In addition, they possessed low‐oxygen impurity content of 0.79 wt% and moderate‐carbon impurity content of 8.98 wt%. Such work provides a novel route to fabricate the ternary or more component TMCs.
Integrating univariate niche dynamics in species distribution models: A step forward for marine research on biological invasions
Authors: D’Amen Manuela , Azzurro Ernesto 
Published: December 2019

AbstractAimThe development of approaches to predict the distribution and potential expansion of invasive species is still an open challenge. Here our goal is to improve the modelling procedure for marine invaders by coupling Species Distribution Models (SDMs) with an analysis of their univariate niche dynamics. In particular, we tested for the first time whether choosing model predictors among the stable niche dimensions was effective in improving predictions of invasive species expansion.LocationMediterranean Sea.TaxonDusky spinefoot, Siganus luridus.MethodsWe analysed the univariate niche dynamics for S. luridus across its native and invaded ranges, by applying a standardized framework that allowed the identification of cases of niche stability or shift. We compared inter‐range transferability of SDMs fitted with different combinations of labile or stable predictors. Finally, we evaluated interactions in SDM settings (calibration area, model technique and predictors set) on models’ predictive ability, using independent data from the most recent phase of invasion.ResultsWe detected a pattern of niche stability for several variables, especially salinity and bathymetry, which positively influenced model inter‐ranges transferability: when the models calibrated in the native range include only stable niche axes, predictive ability is improved. We also identified a shift towards lower surface temperatures in the introduced range, which were almost never experienced by the species before invasion. The model calibrated within the combined ranges was the most ecologically congruent. Also, models calibrated in the invaded range allowed a correct prediction of range expansion, with the predicted suitable areas only slightly underestimated.Main conclusionsWe provide the first evidence that using conserved predictors in SDMs improves inter‐range projections of expanding invasive species. Variable selection, calibration area and modelling technique all matter when modelling invasive species, with important interaction effects. We provide guidelines on how to improve SDMs applications in biological invasion research.
Spatial dynamics of alpine tree lines under global warming: What explains the mismatch between tree densification and elevational upward shifts at the tree line ecotone?
Authors: Feuillet Thierry , Birre Déborah , Milian Johan , Godard Vincent , Clauzel Céline , Serrano‐Notivoli Roberto 
Published: December 2019

AbstractAimMost studies focusing on the alpine tree line responses to climate warming have used either the tree densification within the ecotone or its elevational upshift as indicators. However, it is acknowledged that the relationship between densification and upshift is spatially heterogeneous, making inferences and comparability among studies tricky. The lack of consistent empirical evidence on this potential mismatch and its drivers leads us to focus on this issue in this study. The aim was twofold: (a) to quantify the mismatch between the two processes at a regional scale, and (b) to identify its site‐specific determinants.TaxonPinus uncinata (Ramond ex DC.)LocationFrench eastern Pyrenees.MethodsAn object‐oriented supervised classification procedure was performed on historical (1953) and current (2015) aerial photographs. Based on the resulting rasters, densification of the tree line ecotone and upward shift of the tree line were estimated at the two dates in 191 sites, then standardized, before finally being compared. Three site clusters were derived (no mismatch, densification prevalence and upshift prevalence). After having characterized their spatial patterns through join count statistics, a multinomial logistic regression model was computed to identify the correlates of these clusters among a list of site variables.ResultsNo spatial pattern among the categories of responses emerges at a local scale, but buffers with no mismatch tend to aggregate at a larger scale. Changes in minimum air temperatures, site elevation, mean slope, slope morphometry and lithology appear as significant drivers of the observed mismatch, implying that the relationship between densification and elevational upshift is context specific.Main conclusionsOur findings suggest that both densification and upshift should be considered in quantitative analyses of tree line spatial dynamics, since these two ecological processes are not controlled by the same drivers.
2019 Chinese Hypertension League guidelines on home blood pressure monitoring
Authors: Wang Ji‐Guang , Bu Pei‐Li , Chen Lu‐Yuan , Chen Xin , Chen Yuan‐Yuan , Cheng Wen‐Li , Chu Shao‐Li , Cui Zhao‐Qiang , Dai Qiu‐Yan , Feng Ying‐Qing , Jiang Xiong‐Jing , Jiang Yi‐Nong , Li Wei‐Hua , Li Yan , Li Yong , Lin Jin‐Xiu , Liu Jing , Mu Jian‐Jun , Peng Ying‐Xin , Song Lei , Sun Ning‐Ling , Wang Yan , Xi Yang , Xie Liang‐Di , Xue Hao , Yu Jing , Yu Wei , Zhang Yu‐Qing , Zhu Zhi‐Ming 
Published: December 2019

AbstractIn China, automated blood pressure monitors have been readily available for home use. Home blood pressure monitoring has been indispensable in the management of hypertension. There is therefore a need to establish guidelines for home blood pressure monitoring on the basis of the 2012 consensus document. In this guidelines document, the committee put forward recommendations on the selection and calibration of blood pressure measuring devices, the frequency (times) and duration (days) of blood pressure measurement, and the diagnostic threshold of home blood pressure.
Spousal metabolic risk factors and incident hypertension: A longitudinal cohort study in Iran
Authors: Ramezankhani Azra , Guity Kamran , Azizi Fereidoun , Hadaegh Farzad 
Published: December 2019

AbstractWe investigated the association between metabolic risk factors in one spouse with incident hypertension in the other. Study sample included 1528 men and 1649 women aged ≥20 years from the Tehran lipid and glucose study with information on body mass index (BMI), waist circumference (WC), hypertension, type 2 diabetes mellitus (DM), and dyslipidemia. The hazard ratio (HR) and 95% confidence interval (95% CI) were estimated for the association of spousal metabolic factors and incident hypertension among men and women separately. A total of 604 and 566 cases of incident hypertension were observed in men and women, respectively. Among men, spousal DM was associated with a 40% (CI: 1.07‐1.83) excess risk of hypertension after adjusting for the men's own and their spouse's risk factors including BMI, DM, smoking, and physical activity level. Among women, spousal DM was associated with more than two times (2.11, 1.69‐2.63) higher risk of hypertension. After further adjustment for the women's own and their spouse's risk factors, the association was attenuated and remained marginally significant (1.25, 0.99‐1.58; P value = .053). Having a spouse with DM increases an individual's risk of hypertension, which raises the possibility of using preexisting information of one partner to guide the screening of the other partner.
Changes in brain peptides associated with reproduction and energy homeostasis: Putative roles of gonadotrophin‐releasing hormone‐II and tyrosine hydroxylase in determining reproductive performance in response to daily food availability times in diurnal zebra finches
Authors: Mishra Ila , Agarwal Neha , Prabhat Abhilash , Batra Twinkle , Bhardwaj Sanjay Kumar , Kumar Vinod 
Published: December 2019

AbstractPrevious studies have demonstrated ‘quality‐quantity’ trade‐offs with daily food availability times in zebra finches. Compared with food access ad lib., zebra finch pairs with restricted food access for 4 hours in the morning produced poor quality offspring, whereas those with the same food access in the evening produced fewer but better quality offspring. The present study investigated whether food‐time‐dependent differential effects on reproductive performance involved brain peptides associated with reproduction and energy homeostasis in zebra finches. We measured peptide/protein expression of gonadotrophin‐releasing hormone (GnRH)‐I, GnRH‐II, gonadotrophin‐inhibitory hormone (GnIH), tyrosine hydroxylase (TH), neuropeptide Y (NPY), cocaine‐ and amphetamine regulated transcript (CART) and ZENK (a neuronal activation marker) by immunohistochemistry and mRNA expression of genes coding for the type 2 (DIO2) and type 3 (DIO3) deiodinase by a quantitative polymerase chain reaction in male and female zebra finches that were paired and kept under a 12:12 hour light/dark photocycle at 24 ± 2°C temperature for > 12 months with access to food ad lib., or for only 4 hours in the morning or evening. In both sexes, GnRH‐I, DIO2 and DIO3 expression did not differ significantly between the three feeding conditions, although levels showed an overall food effect. However, in males, GnIH expression was significantly higher in evening‐fed birds compared to ad lib. fed birds. Interestingly, GnRH‐II and TH levels were significantly lower in restricted feeding compared to the ad lib. group and, importantly, GnRH‐II and TH‐immunoreactivity levels were negatively and positively correlated with egg laying latency and reproductive success (offspring/brood/pair), respectively. At the same time, we found no effect on the hypothalamic expression of orexigenic (NPY) and anorexigenic (CART) peptides, or ZENK protein (ie, the neuronal activity marker). These results suggest the involvement of reproductive neuropeptides, with putative roles for GnRH‐II and TH, in the food‐time‐dependent effect on reproductive performance, albeit with subtle sex differences, in diurnal zebra finches, which possess the ability to reproduce year‐round, in a manner similar to other continuously breeding vertebrates.
Complications of botulinum toxin and fillers: A narrative review
Authors: Kassir Martin , Gupta Mrinal , Galadari Hassan , Kroumpouzos George , Katsambas Andreas , Lotti Torello , Vojvodic Aleksandra , Grabbe Stephan , Juchems Eva , Goldust Mohamad 
Published: December 2019

AbstractBackgroundCosmetic surgery and esthetic procedures have become a billion dollar industry owing to the ever‐growing demand of the population to stay young. The injectable treatments including fillers and botulinum toxin have become highly popular because of their quick, predictable and lasting results in the management of facial wrinkles and rejuvenation. Although these treatment modalities are relatively safe, they are associated with certain side effects.AimsIn this review, we will focus on the complications of fillers and botulinum toxin.Patients/MethodsThe literature research considered published journal articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) and reference lists of respective articles. Only articles available in English were considered for this review.ResultsBrow ptosis and asymmetry are common adverse effects of botulinum toxin while the most common adverse effects associated with fillers are the local injection related effects manifesting as erythema, edema, pain, and ecchymosis.ConclusionIt is important that the treating physician is well verse with the various fillers and botulinum toxin complications and their management as some of the complications can be severely debilitating.
Nonsurgical jawline rejuvenation using injectable fillers
Authors: Vazirnia Aria , Braz André , Fabi Sabrina G. 
Published: December 2019

AbstractBackgroundA well‐defined jawline is a critical component in the perception of facial attractiveness in both men and women. Dermal fillers offer a nonsurgical, temporary method of correcting mild‐to‐moderate mandibular bone resorption.AimsThe authors discuss pertinent aspects of anatomy, pathophysiology of aging, patient evaluation, gender considerations, injection technique, and complications in jawline augmentation using injectable fillers.MethodsA brief review of the literature surrounding jawline augmentation using injectable fillers in both men and women, as well as the authors’ experience in this area, is provided.ResultsNonsurgical jawline augmentation using injectable fillers can be performed effectively and safely with adequate background knowledge of the regional anatomy and appropriate patient selection. The authors discuss both injection techniques in the published literature and their own approach. Potential complications are also reviewed.ConclusionJawline rejuvenation is a key component to global facial aesthetic rejuvenation. Therefore, it is important for physicians to understand how to safely and effectively perform nonsurgical jawline rejuvenation using injectable fillers.