bluuebunny/crossref_metadata_2025_split huggingface dataset:
Video cognitive‐behavioral therapy for insomnia in cancer patients: A cost‐effective alternative
Authors: Savard Josée , Ivers Hans , Morin Charles M. , Lacroix Guy 
Published: August 2020

AbstractObjectiveDespite its high prevalence, cancer‐related insomnia typically remains untreated because of a lack of access to cognitive‐behavioral therapy for insomnia (CBT‐I), the treatment of choice for this condition. While face‐to‐face CBT‐I appears to be optimal in terms of efficacy, self‐administered formats may be more cost‐effective. The goal of this secondary analysis of a randomized clinical trial was to compare the cost‐effectiveness of a professionally‐based CBT‐I (PCBT‐I) to that of a video‐based CBT‐I (VCBT‐I).MethodsA total of 161 women with breast cancer received six weekly, individual CBT‐I sessions (PCBT‐I; n = 81) or a 60‐minutes animated video +6 short booklets (VCBT‐I; n = 80). Participants completed the Insomnia Severity Index (ISI) and provided information to calculate treatment costs.ResultsTotal per patient treatment costs were 5.5 times greater for PCBT‐I ($1298.90) than VCBT‐I ($234.36; P < .0001). Both at posttreatment and 3‐month follow‐up, the ISI reduction was greater in PCBT‐I than VCBT‐I, but these differences were not significant (P = .09 and P = .24, respectively). In contrast, the cost‐effectiveness ratio was significantly more advantageous for VCBT‐I than PCBT‐I. Compared to VCBT‐I, each reduction of 1 unit on the ISI produced by PCBT‐I was associated with a treatment cost that was significantly greater at posttreatment ($186.95 CAD vs $44.87 CAD; P = .001) and follow‐up ($154.76 vs $24.97, P = .005).ConclusionsAlthough CBT‐I is slightly less efficacious when self‐administered, it constitutes a much more cost‐effective alternative than face‐to‐face CBT‐I and represents an extremely valuable option in settings where monetary and human resources required to administer CBT‐I are not available or sufficient.
Spiritual peace and life meaning may buffer the effect of anxiety on physical well‐being in newly diagnosed cancer survivors
Authors: Sleight Alix G. , Boyd Patrick , Klein William M. P. , Jensen Roxanne E. 
Published: August 2020

AbstractObjectiveTo assess the extent to which spiritual well‐being moderates the relationship between anxiety and physical well‐being in a diverse, community‐based cohort of newly diagnosed cancer survivors.MethodsData originated from the Measuring Your Health (MY‐Health) study cohort (n = 5506), comprising people assessed within 6‐13 months of cancer diagnosis. Life meaning/peace was assessed using the 8‐item subscale of the Spiritual Well‐Being Scale (FACIT‐Sp‐12). Anxiety was measured with an 11‐item PROMIS Anxiety short form, and physical well‐being was assessed using the 7‐item FACT‐G subscale. Multiple linear regression models were used to assess relationships among variables.ResultsLife meaning and peace was negatively associated with anxiety, b = −0.56 (P < .001) and positively associated with physical well‐being, b = 0.43 (P = <.001) after adjusting for race, education, income, and age. A significant interaction between life meaning/peace and anxiety emerged (P < .001) indicating that spiritual well‐being moderates the relationship between anxiety and physical well‐being. Specifically, for cancer survivors high in anxiety, physical well‐being was dependent on levels of life meaning/peace, b = 0.19, P < .001. For those low in anxiety, physical well‐being was not associated with levels of life meaning/peace, b = 0.01, P = .541. Differences in cancer clinical factors (cancer stage at diagnosis, cancer type) did not significantly impact results.ConclusionsFurther research is needed to assess how spiritual well‐being may buffer the negative effect of anxiety on physical well‐being. A clinical focus on spiritual well‐being topics such as peace and life meaning may help cancer survivors of all types as they transition into follow‐up care.
Botanic garden solutions to the plant extinction crisis
Authors: Westwood Murphy , Cavender Nicole , Meyer Abby , Smith Paul 
Published: August 2020

Social Impact StatementBotanic gardens and arboreta have evolved significantly from their origins as oases reserved for the elite, to the conservation powerhouses they are today, visited by over half a billion people annually. Now, with their sophisticated facilities and botanical expertise, gardens are uniquely positioned to address many of the challenges associated with preserving plant diversity for the benefit of people and the planet. Globally, however, resources for and awareness of these efforts are limited. Funders, governments, corporations, and global citizens need to greatly increase their support of gardens, recognizing the critical role they play in a scientifically informed, coordinated, global effort to save plants from extinction – because all life depends on plants.SummaryOver centuries, botanic gardens and arboreta have evolved considerably in purpose and audience, from a historic focus on teaching and reference collections to championing plant conservation today; gardens fill a major global conservation need at the intersection of horticulture, living collections, plant science, and public education. With a sixth global mass extinction event underway, we are losing plant species before they can even be described, and over 20% of plant species are threatened with extinction. In response to this crisis, gardens are increasingly placing the conservation of plant diversity at the center of their missions, programming, and collections. However, there are significant challenges to preserving the world's vast plant diversity, and plant conservation efforts remain chronically underfunded. We envision a future where gardens have the resources, coordination, and capacity needed to reverse the plant extinction crisis. With sufficient resources, the garden community could: (a) operate an active network of globally coordinated gardens with capacity to carry out integrated plant conservation focused in biodiverse regions; (b) complete threat assessments for all plant species, to inform and prioritize conservation efforts; (c) conserve all “exceptional species” in genetically diverse living collections; and (d) ensure more informed, resilient, and productive landscape restoration efforts are successfully sequestering carbon and supporting biodiversity globally. The garden community is poised to lead these global efforts to preserve and protect plant diversity. Gardens have the expertise, tools, facilities, and networks in place to be the strongest force for plant conservation – they just need the resources to match the global need.
Density functional theoretical tailoring of electronic effect through various substituents on calix[4]arene‐crown‐6 for efficient Cs+ ion encapsulation and extraction
Authors: Boda Anil , Ali Sk. Musharaf 
Published: August 2020

AbstractThe structure, energetic, and quantum chemical descriptors of Cs+ complexes of calix[4]arene‐crown‐6 (C4C6) and substituted C4C6, that is, 1,3 alternate‐diethoxy C4C6, are reported here based on the analysis of results obtained using density functional theory (DFT). Substitution of benzo group in both C4C6 and 1,3 alternate‐diethoxy C4C6 resulted in a reduction of binding energy (BE). Further substitution of the benzo group with methyl, methoxy, and amino groups leads to an increase in BE, and nitro substitution leads to decrease in BE for C4C6, whereas in the case of 1,3 alternate‐diethoxy calix[4]arenebenzocrown‐6, methoxy substitution leads to the highest BE compared to other complexes. The calculated Gibbs free energy, ΔGgas also followed the same order as BE in the case of 1,3 alternate‐diethoxy C4C6 and their substituted ligands. Furthermore, the ΔG of complexation was computed using a thermodynamic cycle with conductor‐like screening model in different solvents: toluene, chloroform, octanol, and nitrobenzene. The values of ΔGext are found to be increased with an increase in the dielectric constant of the solvent and were found to be highest in the nitrobenzene. The atoms in molecule analysis reveals partial ionic character in the CsO bond. Among all the studied complexes, 1,3 alternate‐diethoxy calix[4]arene 3′‐methoxy benzo crown‐6 displays highest ΔGext in nitrobenzene. The calculated value of ∆∆Gext (∆∆G = ∆GCs+ − ∆GNa+) is found to be −41.82 kcal/mol with 1,3 alternate‐diethoxy calix[4]arene 3′‐methoxy benzocrown‐6, which is higher than that obtained with calix [4] bis‐crown‐6 (−5.24 kcal/mol). The newly designed ligand might be suitable for the selective extraction of Cs+ over Na+ in the reprocessing of nuclear waste and thus invites experimentalists to test this DFT finding in the laboratory.
Bronchosubcutaneous fistula manifesting as massive subcutaneous emphysema treated successfully by endobronchial Watanabe spigots
Authors: Yanagiya Masahiro , Hiyama Noriko , Takeshima Hideyuki , Usui Kazuhiro , Matsumoto Jun 
Published: August 2020

AbstractA bronchosubcutaneous fistula (BF) is an abnormal communication between the bronchus, pleural cavity, and subcutaneous tissue. Treatment of BF has been documented rarely. We describe a successful endoscopic bronchial occlusion using endobronchial Watanabe spigots (EWSs) for BF manifesting as massive subcutaneous emphysema (SE). A 78‐year‐old woman developed delayed localized SE following a surgical pleural biopsy for the diagnosis of primary lung cancer. Computed tomography (CT) of the chest revealed BFs resulting from pleural biopsy. The affected bronchi were identified using chest CT. We inserted EWSs into the affected bronchi with the aid of virtual bronchoscopic navigation. This bronchoscopic procedure achieved complete resolution of the SE by sealing the BFs without the need for surgical interventions.
Two‐Coordinate Cu(I) and Au(I) Complexes Supported by BICAAC and CAAC Ligands
Authors: Manar Krishna K. , Chakrabortty Soumyadeep , Porwal Vishal Kumar , Prakash Darsana , Thakur Sandeep Kumar , Choudhury Angshuman Roy , Singh Sanjay 
Published: August 2020

AbstractTwo‐coordinate Cu(I) and Au(I) complexes supported by bicyclic (alkyl)(amino)carbene, [BICAAC‐CuCl] (1), [BICAAC‐CuI] (2), [(BICAAC)2Cu]+[PF6]– (3) and [(BICAAC)2Au]+[AuCl2]– (6) have been synthesized. The reaction of cyclic (alkyl)(amino)carbene, CAACcy with CuCl afforded [CAACcy‐CuCl] (4) and its further reaction with KPF6 gave [(CAACcy)2Cu]+[PF6]– (5). Complexes 1–6 have been characterized by multinuclear NMR, IR and UV‐Vis., spectroscopic method and high‐resolution mass spectrometry (HRMS). Single crystal X‐ray structure of heteroleptic complexes 1 and 4 and homoleptic complexes [(BICAAC)2Cu]+[CuI2]– (2’), 3 and 6 have also been determined. The crystal structure of these complexes confirmed linear two‐coordinate geometry around the metal centers. In the solid‐ state, complexes 1, 2’, 4 and 6 displayed C−H⋯M (M=Cu, Au) and weak non‐covalent C−H⋯X (X=Cl, I) and C−H⋯H−C interactions. Computational calculations correlate well to the experimentally observed geometry and help elucidate the absorption characteristics type of transitions and the frontier orbitals involved in them.
Structure and Magnetic Properties of Two Discrete 3d‐4f Heterometallic Complexes
Authors: Yang Panpan , Yu Shui , Quan Lixia , Hu Huancheng , Liu Dongcheng , Liang Yuning , Li Bo , Liang Fupei , Chen Zilu 
Published: August 2020

AbstractTwo discrete 3d–4f heterometallic complexes [CoIIIDyIII(CH3CN)0.5(L1)3(NO3)3] (1) and [Ni2IIDyIII(EtOH)(L2)4(NO3)2Cl] ⋅ CH3CN (2) were obtained from the reactions of 8‐hydroxyquinoline (HL1) or 2‐methyl‐8‐hydroxyquinoline (HL2) with their corresponding metal salts. Complex 1 presents a dinuclear structure with the Dy(III) and Co(II) ions linked by three phenolic oxygen atoms from three (L1)− ligands. Complex 2 presents a triangular trinuclear structure with the two Ni(II) ions and one Dy(III) ion consolidated by one chloride ligand and four phenolic oxygen atoms from four (L2)− ligands. Their χMT versus T plots show different profiles with obvious ferromagnetic interactions between the metal ions in 2. Both complexes exhibit slow magnetic relaxation behaviours, but with obvious different features. It revealed a cooperatively regulating effect of ligand and transition metal ions on the structures and magnetic properties.
Nickel‐Catalyzed Carbon‐Sulfur Bond Formation through Couplings of Aryl Iodides and Aryl Ethanethioates
Authors: Mao Pu , Sui Hong‐Da , Yuan Jin‐Wei , Xiao Yong‐Mei , Yang Liang‐Ru , Mai Wen‐Peng 
Published: August 2020

AbstractA nickel‐catalyzed reductive coupling between aryl iodides and aryl ethanethioates has been developed to afford diaryl sulfides. This method provides a novel and practical route to aryl thioetherification and can be effectively applied to electronically diverse aryl iodides without expensive metals such as palladium and ruthenium.
INSWF DNAsignal analysis tool: Intelligent noise suppression window filter
Authors: Ahmad Muneer , Ahmad Iftikhar , Bilal Muhammad , Jolfaei Alireza , Mehmood Raja Majid 
Published: August 2020

SummaryDNA signals mainly differ from standard digital signals due to their biological data contents. Owing to unique properties of DNA signals the conventional signal processing techniques, such as digital filters, suffers with spectral leakage and results in insignificant noise suppression in DNA sequence analysis. This article presents an intelligent noise suppression window filter (INSWF) for DNA signal analysis. The filter demises the signal by separating high‐level frequency contents and by identifying nucleotides with high fuzzy membership contribution at particular locations. The nucleotide contents of signals are later filtered by application of median filtering employing a combination of s‐shaped and z‐shaped filters. The fundamental characteristic of codons usage that causes uneven nucleotides segmentation has been tackled by finding the best fit of the curve in biological contents of filter. One of the fuzzy correlations existing between codons and median that nucleotides incorporated to reduce the signal noise to a larger magnitude. TheINSWFfilter outperformed the existing fixed‐length digital filters tested over 250 benchmarked and random datasets of various species. A notable enhancement of 45% to 130% was achieved by significantly suppressing signal noise as compared with conventional digital filters in DNA sequence analysis.
Corporate social responsibility and age of productivity: A study on emerging economies
Authors: Yasser Qaiser Rafique , Mamun Abdullah Al , Zaman Sawlat , Ali Muhammad Jahangir , Bhavani Ganga 
Published: August 2020

AbstractIn this article, we examine whether, and how, positive and negative corporate social responsibility events relate to specific demographic characteristics such as directors' age in Asian emerging economies. Using the upper echelon hypothetical perspective of Hambrick and Mason (1984) and based on evidence gathered on 21,647 directors from Malaysia, Indonesia, Thailand, India, and the Philippines, we find that the demographic characteristics of top management team (TMT), particularly directors' age, has a significant relationship with corporate social responsibilities. Demographic characteristics of directors are an important way to measure individual cognitive bases; cognitive bases in turn combine to create certain team abilities and tendencies, resulting in patterns in board decision outcomes.
Propolis nanoparticles modulate the inflammatory and apoptotic pathways in carbon tetrachloride‐induced liver fibrosis and nephropathy in rats
Authors: Izzularab Batoul Mohamed , Megeed Mervat , Yehia Mona 
Published: August 2020

AbstractThis study assessed the use of emulsion‐produced propolis nanoparticles for treating carbon tetrachloride (CCl4)‐induced liver fibrosis and nephropathy on albino rat model. The evaluation of hepatotoxicity, nephrotoxicity, and the treatment outcomes involved biochemical investigations of blood samples as well as molecular analysis, and histopathological assessment for liver and kidney tissue samples. CCl4 treatment caused elevated biochemical indicators of hepatotoxic and nephrotoxic effects as detected by liver and kidney functions tests, which improved gradually with propolis nanoparticles treatment. The molecular studies showed an increase in transforming growth factor β (TGF‐β), Nephrin, and Caspase‐9, while Bcl‐2 levels dropped in both liver and kidney tissue samples; such changes were normalized after treatment. The histological findings confirm both biochemical and molecular studies. Our results indicated that propolis nanoparticles had an anti‐inflammatory effect as proved by decreased expression of TGF‐β in liver tissue and Nephrin in kidney tissue. The propolis nanoparticles showed an anti‐apoptotic effect on liver and kidney tissue increasing the expression of Bcl‐2 and decreasing the expression of Caspase‐9.
Superradiance and stability of the regularized 4D charged Einstein-Gauss-Bonnet black hole
Authors: Zhang Cheng-Yong , Zhang Shao-Jun , Li Peng-Cheng , Guo Minyong 
Published: August 2020

AbstractWe investigated the superradiance and stability of the regularized 4D charged Einstein-Gauss-Bonnet black hole which is recently inspired by Glavan and Lin [Phys. Rev. Lett. 124, 081301 (2020)]. We found that the positive Gauss-Bonnet coupling constantαenhances the superradiance, while the negativeαsuppresses it. The condition for superradiant instability is proved. We also worked out the quasinormal modes (QNMs) of the charged Einstein-Gauss-Bonnet black hole and found that the real part of all the QNMs does not satisfy the superradiance condition and the imaginary parts are all negative. Therefore this black hole is stable. Whenαmakes the black hole extremal, there are normal modes.
From structural modalities in perinatal medicine to the frequency of preterm birth
Authors: Deindl Philipp , Diemert Anke 
Published: August 2020

AbstractPreterm birth is a global health problem that affects 11% of all live births: it remains a significant cause of death and an important cause of long-term loss of human potential among survivors all around the world. In the last decade, many developed countries have seen an increase in the rate of infants born preterm. Various theoretical and practical concepts have been discussed that aim to optimize the perinatal care of preterm infants and their mothers. These include the definition of hospitals with different levels of care, the regionalization of care, the creation of large care units with high case numbers, and a high level of expertise. This review article focuses on the connection between health care structures and different aspects of preterm birth. Furthermore, this review article highlights the fact that preterm birth is a heterogeneous syndrome with many underlying pathologies and that the causality for a large number of cases remains unexplained. There is still a significant knowledge gap concerning the actual drivers of spontaneous preterm birth, and future research particularly in parturition immunology as well as genetics of prematurity will be essential to identify new targets for therapy.
The role of the l-IPS in the comprehension of reversible and irreversible sentences: an rTMS study
Authors: Vercesi Lorenzo , Sabnis Prerana , Finocchiaro Chiara , Cattaneo Luigi , Tonolli Elena , Miceli Gabriele 
Published: August 2020

AbstractThematic roles can be seen as semantic labels assigned to who/what is taking part in the event denoted by a verb. Encoding thematic relations is crucial for sentence interpretation since it relies on both syntactic and semantic aspects. In previous studies, repetitive transcranial magnetic stimulation (rTMS) over the left inferior intraparietal sulcus (l-IPS) selectively influenced performance accuracy on reversible passive (but not active) sentences. The effect was attributed to the fact that in these sentences the assignment of the agent and theme roles requires re-analysis of the first-pass sentence parsing.
To evaluate the role of reversibility and non-canonical word order (passive voice) on the effect, rTMS was applied over l-IPS during a sentence comprehension task that included reversible and irreversible, active and passive sentences. Participants were asked to identify who/what was performing the action or who/what the action was being performed on.
Stimulation of the l-IPS increased response time on reversible passive sentences but not on reversible active sentences. Importantly, no effect was found on irreversible sentences, irrespective of sentence diathesis.Results suggest that neither reversibility nor sentence diathesis alone are responsible for the effect and that the effect is likely to be triggered/constrained by a combination of semantic reversibility and non-canonical word order. Combined with the results of previous studies, and irrespective of the specific role of each feature, these findings support the view that the l-IPS is critically involved in the assignment of thematic roles in reversible sentences.
Sekundäre Linsenimplantation: chirurgische Techniken und Ergebnisse
Authors: Abela-Formanek Claudette , Reumüller Adrian 
Published: August 2020

ZusammenfassungEs stehen verschiedene alternative chirurgische Optionen zur Verfügung, um eine sekundäre Intraokularlinse (IOL) in Augen mit unzureichender Kapselunterstützung zu implantieren. Erfolgreiche Techniken umfassen die Implantation einer irisfixierten IOL (IFIOL), einer kammerwinkelgestützten Vorderkammerlinse (ACIOL) oder verschiedene Variationen zur Sklerafixierung (SFIOL). Jede dieser Methoden hat sich als sicher und effektiv erwiesen, weist jedoch verfahrensspezifische Einschränkungen auf. Jüngste Studien zeigen, dass die Entwicklung neuer chirurgischer Techniken diesen Patienten weiterhin sichere und reproduzierbare Behandlungsmöglichkeiten bietet. Obwohl die Implantation von sekundären IOLs ohne Kapselunterstützung von vielen Faktoren, einschließlich der Präferenz des Chirurgen, abhängt, sind nahtlose sklerafixierende Techniken für die chirurgische Gemeinschaft von wachsendem Interesse. Das Bestreben nach kürzeren und weniger traumatischen Operationen sowie nach reproduzierbaren und funktionell guten Ergebnissen, fördert dabei die Entwicklung von neuen Operationstechniken, Intraokularlinsen und Instrumenten. Diese Übersichtsarbeit gibt einen Einblick in alte und neue Behandlungsmethoden zur Korrektur von Aphakie mit sekundären Intraokularlinsen
Upstream development ofEscherichia colifermentation process withPhoApromoter using design of experiments (DoE)
Authors: Agbogbo Frank K , Ramsey Phil , George Renija , Joy Jobin , Srivastava Shikha , Huang Mian , McCool Jesse 
Published: August 2020

AbstractIn this work, a fed-batch fermentation development was performed with recombinant E. coli carrying the PhoA promoter system. The phosphate concentrations tested for this PhoA strain, 2.79 mM to 86.4 mM, were beyond the concentrations previously evaluated for cell growth and product titer. The results from the scouting work was used for design of experiments (DoE) where a range of phosphate levels from 27.1 mM to 86.4 mM was simultaneously evaluated with temperature, pH and DO set points. Definitive screening was used to evaluate these parameters simultaneously and the results indicate that fermentation temperature and phosphate content are the major contributors of product titer. The other factors tested such as pH had a minimal effect and DO had no impact on product titer.