bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heteroatom‐Doped and Oxygen‐Functionalized Nanocarbons for High‐Performance Supercapacitors
Authors: Ghosh Subrata , Barg Suelen , Jeong Sang Mun , Ostrikov Kostya (Ken) 
Published: July 2020

AbstractElectrochemical capacitors (best known as supercapacitors) are high‐performance energy storage devices featuring higher capacity than conventional capacitors and higher power densities than batteries, and are among the key enabling technologies of the clean energy future. This review focuses on performance enhancement of carbon‐based supercapacitors by doping other elements (heteroatoms) into the nanostructured carbon electrodes. The nanocarbon materials currently exist in all dimensionalities (from 0D quantum dots to 3D bulk materials) and show good stability and other properties in diverse electrode architectures. However, relatively low energy density and high manufacturing cost impede widespread commercial applications of nanocarbon‐based supercapacitors. Heteroatom doping into the carbon matrix is one of the most promising and versatile ways to enhance the device performance, yet the mechanisms of the doping effects still remain poorly understood. Here the effects of heteroatom doping by boron, nitrogen, sulfur, phosphorus, fluorine, chlorine, silicon, and functionalizing with oxygen on the elemental composition, structure, property, and performance relationships of nanocarbon electrodes are critically examined. The limitations of doping approaches are further discussed and guidelines for reporting the performance of heteroatom doped nanocarbon electrode‐based electrochemical capacitors are proposed. The current challenges and promising future directions for clean energy applications are discussed as well.
Engineering hydrophobically associated hydrogels with rapid self‐recovery and tunable mechanical properties using metal‐ligand interactions
Authors: Panda Prachishree , Dutta Agniva , Ganguly Debabrata , Chattopadhyay Santanu , Das Rajat K. 
Published: July 2020

AbstractIn this contribution, hydrophobic association and metal‐ligand coordination have been employed in a dual physical crosslinking strategy to access hydrogels based on micellar copolymerization of acrylamide and a hydrophobic acrylic monomer (containing terpyridine (terpy) for metal‐ligand interaction). The mechanical properties of these hydrogels are strongly influenced by the thermodynamic stability and kinetic lability of the metal‐terpy crosslinks present in these materials. While the hydrogel tensile strength and stability on water exposure are enhanced by choosing stronger Fe2+‐terpy crosslinks, the weaker and more kinetically labile Zn2+‐terpy coordination bonds enable significantly higher energy dissipation under tensile loading and self‐healing in the resultant hydrogels.
Guidelines for absolute quantitative real‐time PCR for microbial determination in in vitro gastrointestinal digestion
Authors: Zhang Lu , Shi Mengxuan , Tian Meiling , Wang Xuehua , Ji Junfu , Liao Xiaojun , Hu Xiaosong , Chen Fang 
Published: July 2020

AbstractCurrently, numerous pieces of evidence have demonstrated that the health gut microbiota contributed to physiological homeostasis for the host. Accumulating methods appear to detect microbial population, including denaturing gradient gel electrophoresis (DGGE), high‐throughput sequencing, and quantitative real‐time polymerase chain reaction (qPCR). With characteristics of flexibility and high‐sensitivity, qPCR technique plays a critical role in determining the dynamic alteration of bacterial abundances, which entirely exhibits the microbial activity in various external situations. In these guidelines, taking Akkermansia muciniphila for example, we provide experimental details in specific primer design and validation, standard plasmid construction, qPCR assay, and data analysis for microbial detection, which also can be used for bacterial determination in other environmental systems. In addition, we offer the solution preparation and operation procedures of in vitro gastrointestinal digestion system. Furthermore, these guidelines can contribute to verify the high‐throughput sequencing results and reveal the underlying mechanism of the microbial shift in response to the dietary intervention or the development of diseases.
Neur1 and Neur2 are required for hippocampus‐dependent spatial memory and synaptic plasticity
Authors: Lee Jaehyun , Yoon Ki‐Jun , Park Pojeong , Lee Chaery , Kim Min Jung , Han Dae Hee , Kim Ji‐il , Kim Somi , Lee Hye‐Ryeon , Lee Yeseul , Jang Eun‐Hae , Ko Hyoung‐Gon , Kong Young‐Yun , Kaang Bong‐Kiun 
Published: July 2020

AbstractNeur1 and Neur2, mouse homologs of the Drosophila neur gene, consist of two neuralized homology repeat domains and a RING domain. Both Neur1 and Neur2 are expressed in the whole adult brain and encode E3 ubiquitin ligases, which play a crucial role in the Notch signaling pathways. A previous study reported that overexpression of Neur1 enhances hippocampus‐dependent memory, whereas the role of Neur2 remains largely unknown. Here, we aimed to elucidate the respective roles of Neur1 and Neur2 in hippocampus‐dependent memory using three lines of genetically modified mice: Neur1 knock‐out, Neur2 knock‐out, and Neur1 and Neur2 double knock‐out (D‐KO). Our results showed that spatial memory was impaired when both Neur1 and Neur2 were deleted, but not in the individual knock‐out of either Neur1 or Neur2. In addition, basal synaptic properties estimated by input–output relationships and paired‐pulse facilitation did not change, but a form of long‐term potentiation that requires protein synthesis was specifically impaired in the D‐KO mice. These results collectively suggest that Neur1 and Neur2 are crucially involved in hippocampus‐dependent spatial memory and synaptic plasticity.
Prevalence of occult microscopic endometriosis in clinically negative peritoneum during laparoscopy for chronic pelvic pain
Authors: Gubbels Ashley L. , Li Rui , Kreher Donna , Mehandru Natasha , Castellanos Mario , Desai Nita A. , Hibner Michael 
Published: July 2020

AbstractObjective To determine the prevalence of occult microscopic endometriosis in patients with chronic pelvic pain and negative laparoscopy.MethodsA retrospective cross‐sectional study included women who underwent laparoscopic evaluation for chronic pelvic pain by three fellowship‐trained gynecologic surgeons at a community hospital from January 2011 to December 2016. The aim was to evaluate the prevalence of microscopic endometriosis in this population.Results In 142 patients with clinically negative peritoneum on laparoscopy, 39% had occult microscopic endometriosis. Cramping pain score during menses was found to be lower in the positive biopsy group (6.9 vs 8.0, P=0.046). No differences were appreciated in age of menarche, pain during various parts of the menstrual cycle, or duration of symptoms. The biopsy‐positive group had a younger age at time of evaluation, although not statistically significant (P=0.179). Current use of hormones affected neither biopsy results nor menstrual or pain characteristics. Detection was similar between robotic and laparoscopic cases and operative morbidity was minimal.ConclusionOccult microscopic endometriosis may be present in approximately 39% of patients with clinically negative appearing peritoneum undergoing laparoscopy for chronic pelvic pain. Given this, biopsies should be performed in patients undergoing laparoscopy who do not have visible lesions.
The association between in‐class cultural diversity with empathy and bullying in adolescence: A multilevel mediation analysis
Authors: Schultze‐Krumbholz Anja , Ittel Angela , Scheithauer Herbert 
Published: July 2020

Little is known about the associations between cultural class composition, teacher support for diversity (TSD), cognitive and affective empathy, and bullying and victimisation. Research shows that empathy is negatively associated with bullying and victimisation; and support for diversity and classroom cultural diversity are positively linked to social skills. The present study examines whether cultural diversity and perceived TSD are protective factors against bullying and victimisation, either directly or mediated by empathy. Participants were 897 students from Grades 7 to 10 (Mage = 13.45, SDage = 1.07, 51.3% girls, 46.7% boys) in 36 classes. Multilevel mediation analyses were conducted. Age and gender were controlled for. More perceived TSD and affective empathy were associated with less bullying. Moreover, the effect of perceived TSD on bullying was partly indirect through affective empathy. Victimisation was not predicted by the study variables. The class level showed no effects. Bullying and victimisation are complex phenomena, which seem to be linked more to individual than to class characteristics. The result that higher perceived TSD was linked to empathy and bullying provides a promising starting point for measures of competence enhancement and bullying prevention.
The abnormalities of coagulation and fibrinolysis in acute lung injury caused by gas explosion
Authors: Tian Lin‐Qiang , Guo Zhi‐Hao , Meng Wei‐Zheng , Li Long , Zhang Yue , Yin Xiao‐Hang , Lai Feng , Li Yan‐Yan , Feng Li‐Li , Shen Fang‐Fang , Sun Zhen‐Zhou , Yao San‐Qiao , Wu Wei‐Dong , Weng Xiao‐Gang , Ren Wen‐Jie 
Published: July 2020

AbstractAcute lung injury (ALI) caused by gas explosion is common, and warrants research on the underlying mechanisms. Specifically, the role of abnormalities of coagulation and fibrinolysis in this process has not been defined. It was hypothesized that the abnormal coagulation and fibrinolysis promoted ALI caused by gas explosion. Based on the presence of ALI, 74 cases of gas explosion injury were divided into the ALI and non‐ALI groups. The results of prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), and platelet count (PLT) were collected within 24 hours and compared between the groups. ALI models caused by gas explosion were established in Sprague Dawley rats, and injuries were evaluated using hematoxylin and eosin (HE) staining and histopathological scoring. Moreover, the bronchoalveolar lavage fluid (BALF) was collected to examine thrombin‐antithrombin complex (TAT), tissue factor (TF), tissue factor pathway inhibitor (TFPI), and plasminogen activator inhibitor‐1 (PAI‐1) levels by enzyme‐linked immunosorbent assay (ELISA). The patients in ALI group had shorter PT and longer APTT, raised concentration of FIB and decreased number of PLT, as compared to the non‐ALI group. In ALI rats, the HE staining revealed red blood cells in alveoli and interstitial thickening within 2 hours which peaked at 72 hours. The levels of TAT/TF in the BALF increased continually until the seventh day, while the PAI‐1 was raised after 24 hours and 7 days. The TFPI was elevated after 2 hours and 24 hours, and then decreased after 72 hours. Abnormalities in coagulation and fibrinolysis in lung tissues play a role in ALI caused by gas explosion.
New techniques, new challenges—The dilemma of pain management for less invasive surfactant administration?
Authors: Balakrishnan Ashanti , Sanghera Ranveer S. , Boyle Elaine M. 
Published: July 2020

AbstractRecent years have seen the increasing use of noninvasive respiratory support in preterm infants with the aim of minimizing the risk of mechanical ventilation and subsequent bronchopulmonary dysplasia. Respiratory distress syndrome is the most common respiratory diagnosis in preterm infants, and is best treated by administration of surfactant. Until recently, this has been performed via an endotracheal tube using premedication, which has often included opiate analgesia; subsequently, the infant has been ventilated. Avoidance of mechanical ventilation, however, does not negate the need for surfactant therapy. Less invasive surfactant administration (LISA) in spontaneously breathing infants is increasing in popularity, and appears to have beneficial effects. However, laryngoscopy is necessary, which carries adverse effects and is painful for the infant. Conventional methods of premedication for intubation tend to reduce respiratory drive, which increases the likelihood of ventilation being required. This has led to intense debate about the best strategy for providing appropriate treatment, taking into account both the respiratory needs of the infant and the need to alleviate procedural pain. Currently, clinical practice varies considerably and there is no consensus with respect to optimal management. This review seeks to summarize the benefits, risks, and challenges associated with this new approach.
Children’s Password-Related Books: Efficacious, Vexatious and Incongruous
Authors: Renaud Karen , Prior Suzanne 
Published: July 2020

AbstractSoftware is developed specifically for children and this often requires them to authenticate themselves, usually by entering a password. Password hygiene is important for children, because the principles they learn in early life will often endure across their life span. Children learn from their parents, siblings, teachers, and peers. They also learn from educational resources, such as children’s books. We carried out a content analysis of a range of children’s books that aims to educate children about passwords. We used directional coding, as informed by a systematic literature review of methods, such as those used in other content analysis-based studies of children’s books. We examined the principles the books taught, and whether these were correct. We also analysed how the books portrayed the genders of characters, in various roles. We found that principle coverage was variable, with books sometimes teaching outdated principles. Genders were evenly represented in the books. Finally, our analysis revealed conflation of the terms “safety” and “security” in the cyber domain. We conclude the paper by justifying the adjectives we use in the title.
Fabrication of SiCw/Ti3SiC2 composites with improved thermal conductivity and mechanical properties using spark plasma sintering
Authors: Zhou Xiaobing , Jing Lei , Kwon Yong Duk , Kim Jin-Young , Huang Zhengren , Yoon Dang-Hyok , Lee Jaehyung , Huang Qing 
Published: July 2020

AbstractHigh strength SiC whisker-reinforced Ti3SiC2 composites (SiCw/Ti3SiC2) with an improved thermal conductivity and mechanical properties were fabricated by spark plasma sintering. The bending strength of 10 wt% SiCw/Ti3SiC2 was 635 MPa, which was approximately 50% higher than that of the monolithic Ti3SiC2 (428 MPa). The Vickers hardness and thermal conductivity (k) also increased by 36% and 25%, respectively, from the monolithic Ti3SiC2 by the incorporation of 10 wt% SiCw. This remarkable improvement both in mechanical and thermal properties was attributed to the fine-grained uniform composite microstructure along with the effects of incorporated SiCw. The SiCw/Ti3SiC2 can be a feasible candidate for the in-core structural application in nuclear reactors due to the excellent mechanical and thermal properties.
Two simple modifications can potentially change the future of proximal hypospadias surgery. Our series and a review of the literature
Authors: Akkary Rezkalla , Ripepi Mirella , Akokpe orion , Louati Hamdi , Klipfel Clemence , Geiss Stephan 
Published: July 2020

Background/Objective:
To draw a hint towards two simple modifications that could potentially decrease the complication rate.

Patients and Methods:
It was a single center, single operator and retrospective study. All patients with severe hypospadias operated according to koyanagi with or without modifications were presented. The surgical technique was described. Complications like fistula, stenosis, dehiscence and urethral diverticulum were studied.

Results and Limitations:
Nineteen patients were included and presented in a chronological manner. The first four patients were operated according to the original koyanagi technique. The next 15 patients were operated according to koyanagi and the urethroplasty was covered by a tunica vaginalis flap. In 10 of them, glanduloplasty was done primarily and in the last 5 patients, glanduloplasty was done as a secondary procedure. The complication rates were 100% in the original koyanagi group, and 0% in the subset were glanduoplasty was deferred.

Conclusions:
Systematically covering the urethroplasty with a tunica vaginalis flap and deferring the glanuloplasty might ameliorate the results of the koyanagi technique.
Investigation of the Clinical Utility of the BRIEF2 in Youth With and Without Intellectual Disability
Authors: Shishido Y. , Mahone E.M. , Jacobson L.A. 
Published: July 2020

AbstractObjective:Executive function (EF) difficulties are commonly found in youth with intellectual disability (ID). Given mixed results from studies using performance-based EF measures, the EF profile has not been well characterized for this population. No published work has examined the clinical utility of the Behavior Rating Inventory of Executive Function, Second Edition (BRIEF2) in distinguishing EF in ID. We hypothesized that the BRIEF2 would show greater elevations in youth with ID compared to the Average IQ comparison group.Methods:Participants included a large sample of 504 youth (157 in ID group; aged 8–18 years) referred for (neuro)psychological evaluation (2015–2019) and identified as meeting criteria for either ID or Average IQ comparison group.Results:Significant elevations were found across BRIEF2 indices and scales. Only mild elevations were noted in selective cognitive regulation scales within the Average IQ group. Groups differed significantly across all EF dimensions, with greater differences observed in behavioral regulation (Self-Monitoring, Inhibition), Shift, and Working Memory. An elevated but less variable pattern of index scores was noted in ID, while the overall pattern of scaled scores appeared similar between groups.Conclusions:The less variable and consistently elevated profile may suggest fewer EF dimensions in individuals with ID than the model proposed in the test manual. Similar profiles between groups may reflect differences in severity, rather than differences in constructs measured by the EF factors, per se. Additional examination is needed to confirm potential structural differences in EF for youth with ID as measured by BRIEF2, with a clinical implication for greater efficiency of EF assessment in this population.
Sleep Deprived or Concussed? The Acute Impact of Self-Reported Insufficient Sleep in College Athletes
Authors: Riegler Kaitlin E. , Guty Erin T. , Thomas Garrett A. , Arnett Peter A. 
Published: July 2020

AbstractObjective:Sleep deprivation is common among both college students and athletes and has been correlated with negative health outcomes, including worse cognition. As such, the current study sought to examine the relationship between sleep difficulties and self-reported symptoms and objective neuropsychological performance at baseline and post-concussion in collegiate athletes.Method:Seven hundred seventy-two collegiate athletes completed a comprehensive neuropsychological test battery at baseline and/or post-concussion. Athletes were separated into two groups based on the amount of sleep the night prior to testing. The sleep duration cutoffs for these group were empirically determined by sample mean and standard deviation (M= 7.07,SD= 1.29).Results:Compared with athletes getting sufficient sleep, those getting insufficient sleep the night prior to baseline reported significantly more overall symptoms and more symptoms from each of the five symptom clusters of the Post-Concussion Symptom Scale. However, there were no significant differences on objective performance indices. Secondly, there were no significant differences on any of the outcome measures, except for sleep symptoms and headache, between athletes getting insufficient sleep at baseline and those getting sufficient sleep post-concussion.Conclusion:Overall, the effect of insufficient sleep at baseline can make an athlete appear similar to a concussed athlete with sufficient sleep. As such, athletes completing a baseline assessment following insufficient sleep could be underperforming cognitively and reporting elevated symptoms that would skew post-concussion comparisons. Therefore, there may need to be consideration of prior night’s sleep when determining whether a baseline can be used as a valid comparison.
Distribution and validation of genotypic and phenotypic glyphosate and PPO-inhibitor resistance in Palmer amaranth (Amaranthus palmeri) from southwestern Nebraska
Authors: Oliveira Maxwel C , Giacomini Darci A , Arsenijevic Nikola , Vieira Gustavo , Tranel Patrick J , Werle Rodrigo 
Published: July 2020

AbstractFailure to control Palmer amaranth with glyphosate and protoporphyrinogen IX oxidase (PPO)-inhibitor herbicides was reported across southwestern Nebraska in 2017. The objectives of this study were to 1) confirm and 2) validate glyphosate and PPO-inhibitor (fomesafen and lactofen) resistance in 51 Palmer amaranth accessions from southwestern Nebraska using genotypic and whole-plant phenotypic assay correlations and cluster analysis, and 3) determine which agronomic practices might be influencing glyphosate resistance in Palmer amaranth accessions in that location. Based on genotypic assay, 88% of 51 accessions contained at least one individual with amplification (>2 copies) of the 5-enolypyruvyl-shikimate-3-phosphate synthase (EPSPS) gene, which confers glyphosate resistance; and/or a mutation in the PPX2 gene, either ΔG210 or R128G, which endows PPO-inhibitor resistance in Palmer amaranth. Cluster analysis and high correlation (0.83) between genotypic and phenotypic assays demonstrated that EPSPS gene amplification is the main glyphosate resistance mechanism in Palmer amaranth accessions from southwestern Nebraska. In contrast, there was poor association between genotypic and phenotypic responses for PPO-inhibitor resistance, which was attributed to segregation for PPO-inhibitor resistance within these accessions and/or the methodology that was adopted herein. Genotypic assays can expedite the process of confirming known glyphosate and PPO-inhibitor resistance mechanisms in Palmer amaranth from southwestern Nebraska and other locations. Phenotypic assays are also a robust method for confirming glyphosate resistance but not necessarily PPO-inhibitor resistance in Palmer amaranth. Moreover, random forest analysis of glyphosate resistance in Palmer amaranth indicated that EPSPS gene amplification, county, and current and previous crops are the main factors influencing glyphosate resistance within that geographic area. Most glyphosate-susceptible Palmer amaranth accessions were found in a few counties in areas with high crop diversity. Results presented here confirm the spread of glyphosate resistance and PPO-inhibitor resistance in Palmer amaranth accessions from southwestern Nebraska and demonstrate that less diverse cropping systems are an important driver of herbicide resistance evolution in Palmer amaranth.