bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of Meloidogyne javanica on tomato using agro-industrial wastes
Authors: Brito Olivia D.C. , Ferreira Júlio C.A. , Hernandes Isabela , da Silva Elizeu J. , Dias-Arieira Claudia R. 
Published: May 2020

Summary
Nematodes of the genus Meloidogyne are one of the major limiting factors in tomato production and a challenging problem in organic systems. This study aimed to investigate the effect of agro-industrial wastes, their forms of application and doses on tomato plants inoculated with Meloidogyne javanica. First, nematodes were multiplied on tomato under glasshouse conditions to simulate a naturally infested environment. At 60 days after inoculation, plant shoots were removed, new seedlings were transplanted into the pots, and the soil was amended with agro-industrial wastes. Treatments were as follows: rice husk, common bean hull, soybean hull, orange bagasse, poultry litter and waste mixture (wastes mixed in equal proportions) applied in three different forms (raw, powdered and biodigester effluent). A non-treated control and a composted waste mixture were also assessed. At 60 days after transplanting, plants were evaluated for nematode parameters. Powdered bean hulls, soybean hulls, orange bagasse and waste mixture provided the best results and were selected for dose-response investigations. A second experiment was conducted in two periods using, in addition to the selected wastes, a mixture of powdered bean hulls, soybean hulls and orange bagasse. Wastes were applied at doses of 0 (control), 2, 4, 6 and 8 t ha−1. Powdered bean hulls, soybean hulls, orange bagasse and waste mixtures at 5 t ha−1 gave the best nematode control, with reductions of 55-100%. The optimal doses for vegetative growth were 4 t ha−1 in the first period and 5 t ha−1 in the second period.
In dubio pro CPR? The Controversial Status of ‘Do Not Resuscitate’ Imprints on the Human Body – a Swiss Innovation
Authors: Levy Melanie 
Published: May 2020

Abstract
‘Do not resuscitate’ (DNR) imprints on the human body have recently appeared in medical practice. These non-standard DNR orders (e.g., tattoos, stamps, patches) convey the patient’s refusal of resuscitation efforts should he be incapable of doing so. The article focuses on such innovative tools to express one’s end-of-life wishes. Switzerland provides a unique example, as ‘No Cardio-Pulmonary Resuscitation’ stamps and patches have been commercialised. The article discusses the challenging legal questions as to the validity of non-standard DNR orders imprinted on the human body. It analyses the obligation of healthcare providers to honour such orders, either as an advance directive or an expression of an individual’s presumed wishes, and withhold treatment. Finally, the article addresses the balancing of interests between the presumed wishes of an unconscious patient and his best interests of being resuscitated and potentially staying alive, a dilemma facing healthcare providers in a medical emergency.
Analysis of the incidence and baseline predictors of the left ventricular ejection fraction returning to normal after dilated cardiomyopathy in postmenopausal women: a retrospective, observational study
Authors: Yuan Xiaopin , Mao Shuai , Tang Qizhu 
Published: May 2020

Objective To analyse the incidence and baseline predictors of the left ventricular ejection fraction (LVEF) returning to normal after dilated cardiomyopathy (DCM) following intervention with standard anti-heart failure (HF) medication in postmenopausal women. Methods Data from consecutive postmenopausal women who were first diagnosed with DCM and received anti-HF treatment during 2011 to 2018 were prospectively retrieved. The study population was divided into the LVEF recovery (LVR) group and the LVEF unrecovered (LVU) group according to whether LVEF was > 50%. The primary endpoint was baseline predictors of LVEF returning to normal. Results LVEF returned to normal in 49.3% (210/426) of patients with DCM. LVEF was significantly higher in the LVR group than in the LVU group (57.4% ± 6.9% vs 44.2% ± 5.3%; hazard ratio 1.312, 95% confidence interval 1.015–1.726) at the final follow-up. High systolic pressure, a short history of HF, a short QRS interval, a small left ventricular end-diastolic diameter (LVEDd), and high LVEF at admission were independent predictors of LVEF returning to normal. Conclusions LVEF returning to normal in postmenopausal women with DCM who receive standard anti-HF treatment is associated with systolic pressure, a history of HF, QRS interval, LVEDd, LVEF at admission, and favourable outcome.
Influences of Cardiovascular Fitness and Body Fatness on the Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis
Authors: Lee Junga 
Published: May 2020

Objective: The purpose of this meta-analysis was to investigate the associations between combined cardiovascular fitness, obesity, and the risk of metabolic syndrome. Data Sources: The MEDLINE and EMBASE databases were used to select relevant studies that included the relative risk (RRs) of metabolic syndrome based on the combined effects of cardiovascular fitness and obesity from January 1990 to July 2019. Study Inclusion and Exclusion Criteria: The inclusion criteria were providing the RRs for the associations between combined cardiovascular fitness and obesity and the risk of metabolic syndrome. The exclusion criteria were review studies, duplicated studies, and no RRs reported for those associations. Data Extraction: All selected studies categorized levels of cardiovascular fitness (high cardiovascular fitness vs low cardiovascular fitness) and obesity (normal vs obesity) and directly extracted the RRs for the risk of metabolic syndrome from these data. All selected studies were cross-sectional studies. Data Synthesis: All RRs and 95% CIs from the selected studies were computed to find the associations between combined cardiovascular fitness and obesity and the risk of metabolic syndrome. Results: A total of 8 studies were selected for this meta-analysis. Low cardiovascular fitness was associated with 3. Fifty-nine times increased metabolic syndrome risk regardless of obesity (3.59, 95% CI: 3.07-4.20; P = .00). And obesity was associated with 1.62 times increased metabolic syndrome risk regardless of cardiovascular fitness level (1.62, 95% CI: 1.32-1.98; P = .00). Lastly, the risk of metabolic syndrome decreased by 77% with high cardiovascular fitness regardless of obesity (0.23, 95% CI: 0.12-0.43; P = .00). Conclusions: The combined effects of cardiovascular fitness and obesity are important factors when determining metabolic syndrome risk. The minimum level of cardiovascular fitness is 8.39 metabolic equivalent (METs) for adults to lower the risk of metabolic syndrome. Enhanced cardiovascular fitness and maintaining normal weight should be recommended for individuals to reduce the risk of metabolic syndrome.
A Study of the Mechanism of Government Intervention on Excess Capacity Through the Enterprise Overinvestment in China
Authors: Hu Biliang , Liu Zhiyi , Fan Sha 
Published: May 2020

This article summarizes government publications focusing on excess capacity from the 1990s to 2016 and argues that the market-oriented principle needs to be established to deal with the long-standing excess capacity issues in China. Based on the specificity of the long-term excess capacity in China, this article puts forward the hypothesis: The excess capacity in China is derived from the enterprise’s overinvestment, and the government intervention is one of the main drivers of the problem. The intervention is actuated by the GDP-based government performance assessment through such means as offering privileges on land use, environmental ignorance, natural resource provision and financial support. This article (a) calculates capacity utilization of 30 manufacturing industries, (b) builds a ‘mediation effect model of overinvestment’, and (c) makes use of the industrial data, economic development data and capacity utilization from 1998 to 2017 to test the hypothesis. The result shows that government intervention indeed has a significant influence on excess capacity. The support for land use and the tolerance for environmental pollution are two of the most persuasive reasons. Therefore, the Chinese government needs to make greater efforts to deepen the market reforms, standardize and improve the factor market so as to accelerate innovation, and push for industrial upgrading.
Long-term Autograft Harvest Site Pain After Ankle and Hindfoot Arthrodesis
Authors: Baumhauer Judith F. , Glazebrook Mark , Younger Alastair , Quiton Jovelyn D. , Fitch David A. , Daniels Timothy R. , DiGiovanni Christopher W. 
Published: May 2020

Background: Pain following autograft harvest has been studied; however, published literature has typically focused on the iliac crest with follow-up limited to only a few years. It remains unknown if pain continues or improves over time. The purpose of this study was to evaluate long-term pain associated with autograft harvest to supplement hindfoot or ankle arthrodesis. Methods: Subjects in the control arm of a previously conducted trial comparing autograft with a synthetic bone graft for hindfoot or ankle arthrodesis were invited back for a single visit at a minimum of 5 years following their initial surgery. Harvest site, fusion site, and weight-bearing pain were evaluated using a 100-point visual analog scale (VAS). Of the 130 invited subjects, 60 (46.1%) returned for assessment, 58 of whom completed pain assessments. Results: At a mean follow-up of 9.0 years (range, 7.8-10.5), more than a third (36.6%) of subjects had some level of harvest site pain. Using VAS greater than 20 mm as a threshold of clinical significance, pain remained clinically significant in 5.2% of subjects. There was a significant correlation between harvest site pain and both weight-bearing and fusion site pain. There was not a significant correlation between harvest site pain and volume of graft harvested. Conclusion: Autograft harvest can result in chronic, clinically significant pain that can last up to 10 years. In the era of shared decision making, this information will help surgeons and patients quantify the risks of chronic pain after arthrodesis procedures that include a secondary operative incision for graft harvest. Level of Evidence: Level II, prospective comparative study.
Comorbidity as a mediator of depression in adults with congenital heart disease: A population-based cohort study
Authors: Yang Hsiao-Ling , Chang Nien-Tzu , Wang Jou-Kou , Lu Chun-Wei , Huang Yong-Chen , Moons Philip 
Published: May 2020

Background
The population of adults with congenital heart disease (CHD) has increased dramatically with a high prevalence of acquired cardiac and non-cardiac comorbidities. However, the relationship among congenital heart disease, physical comorbidities, and psychological health in this population is not well studied.

Aims
The purpose of this study was to investigate (a) the association between adult congenital heart disease and the occurrence of depression and (b) whether physical comorbidities mediated the association between congenital heart disease and the occurrence of depression.

Methods
This retrospective cohort study was followed from 1 January 2010–31 December 2013, based on the data from the National Health Insurance Research Database 2010 in Taiwan. We used mediation analysis in survival data to assess the mediated effect. The hazard ratios were adjusted by age, sex, area of residence, and estimated propensity scores.

Results
We recruited 2122 adult congenital heart disease patients and 8488 matched controls. Nearly half of patients diagnosed with simple congenital heart disease, 39.0% had complex congenital heart disease, and 11.2% had unclassified congenital heart disease. Adult congenital heart disease patients had a significantly higher risk of depression than matched controls (adjusted hazard ratio = 1.43 and 1.48, for all and complex congenital heart disease, respectively, p&lt;0.05). Coronary artery disease and chronic obstructive pulmonary disease were the significant comorbidities mediating the relationship between adult congenital heart disease and depression, the proportions mediated by coronary artery disease or chronic obstructive pulmonary disease were 35.5% and 12.9%, respectively.

Conclusions
Helping patients to prevent psychological and physical acquired disease is imperative. Coronary artery disease is a potent mediator between congenital heart disease and depression, especially for patients with complex congenital heart disease.
Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib
Authors: Ono Atsushi , Aikata Hiroshi , Yamauchi Masami , Kodama Kenichiro , Ohishi Waka , Kishi Takeshi , Ohya Kazuki , Teraoka Yuji , Osawa Mitsutaka , Fujino Hatsue , Nakahara Takashi , Murakami Eisuke , Miki Daiki , Kawaoka Tomokazu , Abe-Chayama Hiromi , Zhang Peiyi , Liu Songyao , Makokha Grace Naswa , Tsuge Masataka , Imamura Michio , Hayes C. Nelson , Chayama Kazuaki 
Published: May 2020

Background: Although lenvatinib was recently approved for treatment of advanced unresectable hepatocellular carcinoma (HCC) based on the phase III REFLECT trial, no biomarkers for management of lenvatinib treatment have been established. The aim of this study is to identify predictive biomarkers for the management of lenvatinib treatment in advanced HCC patients. Methods: A total of 41 patients with advanced HCC were enrolled in this retrospective study. Serum levels of 22 circulating cytokines and angiogenic factors (CAFs) were measured by multiplex Luminex assay. Profiles of CAFs, clinical chemistry/hematology parameters, and clinical background were evaluated to explore biomarkers associated with clinical outcomes. Results: Relative dose intensity (RDI) decreased significantly between weeks 1–2 and 3–4 ( p < 0.001), and RDI during weeks 3–4 was a prominent indicator of progression-free survival (PFS). A signature based on baseline serum levels of nine CAFs associated with low RDI was identified. In a multivariate Cox regression analysis, patients with a favorable 9-CAFs signature [hazard ratio (HR) 0.42, 95% confidence interval (CI) 0.18–0.96, p = 0.040] had lower risk, and Child-Pugh grade B (HR 1.6, 95% CI 1.1–8.3, p = 0.026) and presence of macrovascular invasion (MVI; HR 2.9, 95% CI 1.0–8.3, p = 0.045) had higher risk of shorter PFS. Conclusion: This study demonstrates that RDI is an important predictive factor for longer PFS during lenvatinib treatment. In this hypothesis-generating exploratory analysis, we report that a CAF-signature associated with adverse events and RDI could predict PFS, which might contribute to improved management of lenvatinib treatment in HCC patients.
Outcomes of Partial Meniscectomy in Obese Patients: A Systematic Review and Meta-Analysis
Authors: Zhang Tina , Jauregui Julio J. , Foster Michael , Packer Jonathan D. , Meredith Sean J. , Leong Natalie L. , Henn R. Frank 
Published: May 2020

Objective Arthroscopic partial meniscectomy (APM) is one of the most commonly performed surgical procedures. However, the indications for APM are controversial and obese patients may have worse outcomes. This study’s primary purpose was to investigate differences in outcome after APM associated with elevated body mass index (BMI). Secondary objectives included differences in pathophysiology, surgical complications/failures, or osteoarthritis development. Design MEDLINE, EMBASE, and OVID databases were systematically searched for eligible studies reporting on APM outcomes at a minimum of 1 year postoperatively. Studies that did not include BMI categorization were excluded. Meta-analysis was conducted with random-effects modeling where data from at least 2 studies was available. Results A total of 16 articles were included. Overweight/obese BMI was associated with worse preoperative Lysholm (mean difference, −6.06 [95% CI, −11.70 to −0.42]) and visual analogue scale pain scores (0.43 [0.07 to 0.79]). Worse postoperative normalized knee-specific patient-reported outcome scores were also associated with obese BMI (−4.57 [−5.33 to −3.81]). There were no significant differences in clinical improvement or osteoarthritis progression among BMI groups. Two studies found higher complication/failure rates, 3 articles associated medial meniscus posterior root tears, and 1 article found differences in gene transcript expression with increased BMI. Conclusions Obesity is associated with worse knee function after APM, and patients with elevated BMI have worse preoperative knee pain and function. However, there is no difference in amount of improvement between elevated and normal BMI patients. Further prospective research is necessary to determine the comparative effectiveness of APM in patients with elevated BMI.
Consumer satisfaction–based social commerce service quality management
Authors: Shin Nina , Park Sangwook , Kim Hyunjung 
Published: May 2020

Social commerce (s-commerce) is a social media service enabling consumers’ participation in the online marketing and sale of products and services. This study aims to (a) identify key functional and hedonic quality factors that affect consumer satisfaction based on consumers’ perspective and (b) analyze the degree of efficiency of the quality–satisfaction relationship to propose distinct and actionable improvement strategies from the firms’ perspective. The results identified the following key quality determinants: functional aspects of durability and safety, and hedonic aspects of enjoyment, awareness, novelty, and image. The result implies that most s-commerce service firms fail to efficiently convert the enhancement of safety, awareness, and novelty into consumer satisfaction. This study contributes to the stream of literature on both s-commerce and service operations management by determining key service quality elements based on consumers’ perceptions and providing a decision-making aid to firms for quality-satisfaction efficiency improvement. JEL CLASSIFICATION: M10; L20; L81
Progress in Bio-inspired Anti-solid Particle Erosion Materials: Learning from Nature but Going beyond Nature
Authors: Zhang Shuaijun , Zhang Junqiu , Zhu Bin , Niu Shichao , Han Zhiwu , Ren Luquan 
Published: May 2020

AbstractSolid particle erosion is a common phenomenon in engineering fields, such as manufacturing, energy, military and aviation. However, with the rising industrial requirements, the development of anti-solid particle erosion materials remains a great challenge. After billions of years of evolution, several natural materials exhibit unique and exceptional solid particle erosion resistance. These materials achieved the same excellent solid particle erosion resistance performance through diversified strategies. This resistance arises from their micro/nanoscale surface structure and interface material properties, which provide inspiration for novel multiple solutions to solid particle erosion. Here, this review first summarizes the recent significant process in the research of natural anti-solid particle erosion materials and their general design principles. According to these principles, several erosion-resistant structures are available. Combined with advanced micro/nanomanufacturing technologies, several artificial anti-solid particle erosion materials have been obtained. Then, the potential applications of anti-solid particle erosion materials are prospected. Finally, the remaining challenges and promising breakthroughs regarding anti-solid particle erosion materials are briefly discussed.
Airway management in children with hemifacial microsomia: a restropective study of 311 cases
Authors: Xu Jin , Deng Xiaoming , Yan Fuxia 
Published: May 2020

Abstract
Background
Hemifacial microsomia (HFM) is a congenital craniofacial malformation which is associated with difficult airway. Anesthesiologists may experience difficult intubation in children with HFM. Mandibular distraction could increase the length of the mandible. Theoretically, it should be advantageous to laryngeal view during tracheal intubation. This study reviewed airway management in children with HFM, assessed the efficiency of direct laryngoscopy versus airway-visualizing equipment during the tracheal intubation and determined whether mandibular distraction could improve the laryngoscopic view in children with HFM.

Methods
A retrospective review of cases involving children with HFM aged 5 to 17 years old underwent anesthesia from December 2016 to April 2019 at a single center was performed. The demographic data, preoperative airway assessments, procedure type, anesthetic technique, method of airway management, anesthetists’ comments on mask ventilation, laryngoscopy and intubation parameters were collected.

Results
At last, 136 HFM children entered this study, a total of 311 anesthesia procedures were completed during the study period. Face mask ventilation was possible for most of children except 1 child (bilateral involvement) required two practitioners. The success rates of intubation for the primary video laryngoscopy and fibroscopy were both 100%, but 79.5% for direct laryngoscopy (P < 0.001). 95 (38.9%) children who had difficult laryngoscopic view (DLV) were significantly correlated with failed direct laryngoscopy (P < 0.001). Airway-visualizing equipment (video laryngoscope and Fiberscope) was the primary airway technique in 3 (75%) bilaterally involved children. 60 children underwent both mandibular distraction osteogenesis and the removal of distractor. The laryngoscopic views improved in 26 (43%) children after treatment with mandibular distraction (P < 0.001).

Conclusions
Airway-visualizing equipment can be effectively utilized for intubation in HFM children with DLV. Mandibular distraction could improve the laryngeal view effectively.
Which factors influence the ED length-of-stay after anterior shoulder dislocations: a retrospective chart review in 716 cases
Authors: Schuur Daan , Baden David , Roetman Martijn , Boeije Tom , Burg Michael , Mullaart-Jansen Nieke 
Published: May 2020

AbstractBackgroundAnterior shoulder dislocations (ASD) are commonly seen in Emergency Departments (ED). ED overcrowding is increasingly burdening many healthcare systems. Little is known about factors influencing ED length-of-stay (LOS) for ASD. This study defines the factors influencing ED LOS for ASD patients.MethodsRetrospective chart reviews were performed on all patients ≥12 years admitted with an anterior shoulder dislocation at two regional hospitals in the Netherlands between 2010 and 2016. The electronic patient records were reviewed for baseline patient characteristics, trauma mechanism, reduction methods, medication used, complications and the LOS at the ED. The main objective was determining factors influencing the LOS in patients with an anterior shoulder dislocation at the ED.ResultsDuring the study period, 716 ASD occurred in 574 patients, 374 (65.2%) in males. There were 389 (54.3%) primary ASD; the remainder (327, 45.7%) were recurrent. Median LOS was 92 min (IQR 66 min), with a significantly shorter LOS in those with recurrent dislocations (p < 0.001), younger age group (p < 0.03) and in patients who received no medications in the ED (p < 0.001). Traction-countertraction and leverage techniques were associated with a significant more use of ED medication compared to other techniques. Although the use of more medication might suggest the LOS would be longer for these techniques, we did not find a significant difference between different reduction techniques and LOS.ConclusionTo our knowledge this study is the largest of its kind, demonstrating ED LOS in ASD patients is influenced by age, the need for medication and dislocation history, primary versus recurrent. Notably, we found that biomechanical reduction techniques, which are not primarily traction-countertraction or leverage techniques, e.g. scapular manipulation and Cunningham, were associated with less ED medication use. Further research is needed to define how reduction methods influence ED medication use, patient satisfaction and ED throughput times.