bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of alloxan on induction of diabetes in albino rats
Authors: . Soni , Mishra A. N. 
Published: November 2019

Background: Alloxan-induced diabetes model is used as a “study tool” to elucidate the pathophysiology of the disease and much more as a “search engine” for antidiabetic compounds with better therapeutic characteristics. It was the first agent used in the category of chemically induced diabetes to create a model of insulin dependent diabetes mellitus. Other chemicals being streptozocin, dexamethasone, insulin antibodies-induced diabetes.Methods: Albino rats were divided into four groups with ten rats in each group. Alloxan monohydrate 2%, solution which was dissolved in 0.9% of sodium chloride (normal saline) as a diluent and given intraperitoneally to rats and blood glucose estimation made by using glucometer. Total 40 albino rats were taken and divided into 4 groups. 10 rats receiving normal saline were grouped as Group A, 10 rats received alloxan at a dose of 150 mg/kg as Group B, 10 rats received alloxan at a dose of 160 mg/kg as Group C and 10 rats received alloxan at a dose of 170 mg/kg as Group D.Results: Highest rate of mortality and alopecia were noted in group D receiving alloxan at a dose of 170 mg/kg whereas highest percentage of fluctuation in fasting blood glucose range was seen in group C receiving alloxan at a dose of 160 mg/kg.Conclusions: Such unpredictable response shows that alloxan is not ideal drug for induction of diabetes in experimental animal. Mortality, fasting blood glucose returning to non-diabetic range and alopecia are the chief drawbacks.
Lefamulin: novel pleuromutilin drug for community acquired bacterial pneumonia
Authors: Dubey A. P. , Maggo Sachin , Karan Awanish , Singh N. K. , Bhaskaran Sreya 
Published: November 2019

The advent and spread of antimicrobial resistance has led to a global public health emergency necessitating development of new antimicrobial drugs. Community acquired bacterial pneumonia (CABP) contributes a major portion of societal burden with increasing morbidity due to evolution of drug resistant strains. Lefamulin is a novel pleuromutilin antibiotic with unique mechanism of action through inhibition of protein synthesis by binding to the peptidyl transferase center of the 50s bacterial ribosome. The drug displays activity against Gram positive and atypical organisms associated with CABP (i.e., Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumonia, Legionella pneumophila, and Chlamydophila pneumoniae), with an expanded Gram-positive spectrum including Staphylococcus aureus (i.e., methicillin-resistant, vancomycin-intermediate, and heterogeneous strains). Lefamulin is available in both intravenous (IV) and per oral (PO) formulation, exhibits high nonlinear plasma protein binding with low unbound concentrations, higher concentrations in lung epithelial lining fluid (ELF) than in plasma, and a half-life of approximately 10 hour. The recommended IV dose is 150 mg twice daily over 1 hour or a PO dose of 600 mg twice daily. Most common adverse drug reactions injection site reactions, hepatic enzyme elevation, nausea, diarrhoea, hypokalemia, insomnia, and headache. Clinical trials for lefamulin have been positive and Phase 3 data suggest similar efficacy when compared to moxifloxacin with or without linezolid in CABP. Also, the documented resistance and cross-resistance with other Gram-positive antibacterials remains low. With Nabrivia Pharmaceuticals having already received US FDA approval in August 2019, lefamulin may soon be a new addition to the mounting armoury of drugs against CABP.
Preeclampsia y riesgo cardiovascular: estudio de seguimiento en la Población de GenPE en Colombia
Authors: Serrano-Díaz Norma Cecilia , Páez-Leal María Carolina , Beltrán-Avendaño Mónica Andrea , Colmenares-Mejìa Claudia Carolina , Guio-Mahecha Elizabeth , Bautista-Niño Paula , Lista completa al final del documento Colaboradores 
Published: November 2019

Introducción: las mujeres con antecedente de preeclampsia (PE) tienen mayor riesgo de desarrollar enfermedad cardiovascular. El estudio GenPE ha captado gestantes con y sin PE en Colombia durante diez años, haciendo posible hoy evaluar desenlaces cardiovasculares en este grupo.Objetivo: determinar la presencia de enfermedad cardiovascular en mujeres jóvenes expuestas o no a preeclampsia, captadas por el estudio GenPE en Bucaramanga, Colombia.Materiales y métodos: estudio de cohorte que incluyó 106 pacientes –a partir de la cohorte original, 666 pacientes (2005-2010)–, menores de 26 años, primigestantes, sin antecedentes de enfermedades crónicas. Se realizó examen físico y venopunción para glucemia, perfil lipídico, ácido úrico y apolipoproteínas A-I y B. Se evaluó la presencia de hipertensión arterial (HA), obesidad, diabetes mellitus tipo 2 y síndrome metabólico. Se establecieron diferencias entre las mujeres expuestas y no expuestas a preeclampsia y el cambio entre el ingreso a GenPE y el primer seguimiento mediante test Wilcoxon o chi cuadrado y riesgo relativo con IC 95%.Resultados: se encontró asociación entre la exposición a PE con cifras mayores de presión arterial diastólica (p = 0,003) e hipercolesterolemia (p = 0,040). En toda la población existen niveles subóptimos de colesterol HDL y Apo A-I. Al primer seguimiento no se evidencia asociación con desenlaces fuertes, tales como: hipertensión arterial, obesidad, diabetes mellitus tipo 2, síndrome metabólico.Conclusión: en una muestra de mujeres colombianas jóvenes expuestas y no expuestas a PE, en un primer seguimiento, en los primeros dos años posteriores al parto, se evidencian cambios en la presión arterial diastólica (PAD), y biomarcadores asociados a riesgo cardiovascular.
Pencarian Pola Asosiasi Keluhan Pasien Menggunakan Teknik Association Rule Mining
Authors: Rosyidah Ulya Anisatur , Oktavianto Hardian 
Published: November 2019

Perkembangan dan pertumbuhan data di bidang kesehatan semakin meningkat dan bertambah, baik dari kualitas maupun kuantitas, dilihat dari sisi kualitas, perkembangan data ini mengalami perubahan dari bentuk dokumen tulis menjadi dokumen digital atau yang biasanya kita sebut dengan file. Isu yang muncul adalah apakah informasi yang bisa diambil atau didapatkan dari sekian banyak data medis yang tersedia hanya berupa informasi – informasi pada umumnya, sedangkan dari suatu basis data yang tersedia seringkali memuat beberapa variabel sekaligus, bahkan apabila diteliti lebih jauh lagi, basis data yang berbeda bisa jadi memuat beberapa variabel yang sama, dari isu tersebut maka diperlukan suatu metode untuk bisa menggali lebih dalam informasi – informasi yang belum diketahui. Berkaitan dengan data medis serta data mining, maka penelitian kali ini akan membahas tentang implementasi atau kegunaan dari data mining pada data kunjungan pasien dengan cara menerapkan association rule mining untuk mendapatkan pola – pola asosiasi dari basis data kunjungan pasien yang tersedia menggunakan algoritma apriori dan algoritma FP-Growth. Baik algoritma apriori dan algoritma FP-Growth menghasilkan output yang sama. Perbedaan hasil uji coba terletak pada jumlah rule asosiasi yang ditemukan, dengan menggunakan algoritma apriori ditemukan 3 buah rule asosiasi, sedangkan ketika digunakan algoritma FP-Growth ditemukan 2 buah rule asosiasi, hal ini terjadi pada saat uji coba yang dilakukan menggunakan confidence sebesar 80%.
Rekomendasi Pemilihan Produk Simpanan Tabungan Bank Menggunakan Metode Weighted Product (WP)
Authors: Purnomo Agus Sidiq , Ariyanti Jevi 
Published: November 2019

Many banks in Indonesia, both public and private banks, offer different advantages to the customers. As a result, it is often difficult for the public to decide where to save their money. For this reason, the writer propose a decision support system to help recommend a bank as a smart solution for saving.
This study employed the Weighted Product (WP) with seven criteria, namely initial deposit, subsequent deposits, administrative costs, depositional balances, interest rates, age range, and facilities. This system can help the prospective customers determine the ideal savings place for the future needs. This study shows that the highest final value after calculation is 0.0320 for Batara of BTN bank, and the lowest value is 0.0132 for Tapres of BCA bank.
The Optimization of Tuna Fish and Banana Blossoms into Abon Modified Products in Puger District, Jember Regency
Authors: Rohmawati Ninna , Moelyaningrum Anita Dewi , Witcahyo Eri 
Published: November 2019

Puger is the largest fish producing sub-district in Jember district, which also has a prevalence of high nutritional problems. During this time there are “mitra” who are a group of fish processors and marketers (POKLAHSAR) namely "Ekonomi Puger Bahari (EPB)" and "Duta Tongkol" who try to explore the potential of fish in Puger District. Tuna fish abon produced by “mitra” has a soft texture (srundeng like) so that it is less preferred by consumers therefore this paper argues that there's a need to add banana blossoms as a compound, does not have P-IRT (product permit), and the marketing of the product is not optimal. The author believes that if there is a need for development in terms of products implemented in several respects, among others: 1) Training on modified abon production; 2) Management of P-IRT; 3) Training in business financing and marketing management; 4) Production and marketing assistance. This activity can help partner problems. Expected targets and outcomes, namely: 1) Abon modified tuna and banana heart products that have P-IRT, high protein content is expected to be a solution to KEP nutritional problems; 2) The method of business financing management and appropriate marketing management has been achieved. In addition to directly, partners have marketed their products through social networks and resellers. Partners experience additional turnover and number of buyers; 3) Mastery of skills in the form of skills makes modification abon. This activity has an impact on up-dating science and technology in partners.
Keywords: abon modified; tuna fish; banana blossom; optimization.
Promotion of Can Macanan Kaduk Traditional Arts Through Audio Visual Technology
Authors: Raharsono A Lilik Slamet , Rahardjo Christanto Pudji 
Published: November 2019

Jember Regency is one of the regencies in East Java Province. Here, the growth and development of the culture are extremely rapid and cultural diversity has spread through the southern and northern regions with its respective uniqueness. The southern region is famous for its Javanese culture and the northern region with its Madurese culture. This has led to a combination of the two cultures, resulting in a performing art that is the combination of Javanese and Madurese culture, known as Can Macanan Kaduk. This traditional performing art is an art in Jember that is still maintained by some people. It is needed to support the creation of this performing art and promote it through audio-visual marketing technology so that it will ultimately become widespread and will be better known by the other people outside of Jember. To realize the program objectives, coaching and mentoring has been carried out, regarding the performing arts management with the artists of Can Macanan Kaduk. We create audio-visual work for them to help promote Can Macanan Kaduk. The promotion materials are based on audio-visual technology, consisting of the documentary film, profile videos, and audio-visual advertisement. Through audio-visual promotion and online marketing in websites and offline marketing in DVDs, it is hoped that this traditional performing art, Can Macanan Kaduk, will be widely recognized and gain stronger attention from foreigners, becoming a traditional performing art that characterizes the cultural identity of the Jember Regency.
Key Words: Audio Visual Technology, Can Macan Kaduk, Promotion.
Penerapan Entrepreneural Marketing Pada Kelompok Usaha Ekonomi Kreatif (Creativepreneur) di Desa Pakis Dalam Upaya Penguatan Desa Pakis Sebagai Desa Sejahtera Mandiri (DSM)
Authors: Kartika Intan , Molasy Honest Dody , Magfiroh Illia Seldon 
Published: November 2019

Universitas Jember memiliki kontribusi yang cukup besar dalam mengupayakan pengentasan kemiskinan di Desa Pakis. Bekerjasama dengan Kementerian Sosial Republik Indonesia, Universitas Jember telah menetapkan Desa Pakis sebagai Desa binaan yang mendapatkan program Desa Sejahtera Mandiri (DSM). Salah satu upaya yang bisa dilakukan untuk mengentaskan kemiskinan dan menciptakan kemandirian desa adalah dengan mendirikan Kelompok Usaha Ekonomi Kreatif (Creativepreneur). Tujuan pengabdian ini adalah Melakukan pendampingan dan edukasi kepada mitra Kelompok Ekonmi Kreatif Desa Pakis mengenai (a) pemasaran produk dengan menerapkan Entrepreneural Marketing, (b) pengolahan produk berbasis potensi pertanian lokal dan pembuatan kerajinan tangan berbasis limbah produk, (c) strategi pengembangan bisnis dan analisis usaha, (d) manajemen organisasi usaha dan masyarakat. Kegiatan pengabdian PPK mulai dilaksanakan pada bulan Oktober tahun 2018 sampai dengan awal Desember 2018. Metode pelaksanaan dilakukan melalui tahapan (1) identifikasi permasalahan mitra, (2) sosialisasi kegiatan, (3) edukasi Entrepreneural Marketing, (4) pelatihan pembuatan kerajinan tangan, (5) pelatihan produk olahan berbasis potensi local, (6) edukasi analisis usaha, strategi pengembangan usaha serta manajemen organisasi dan masyarakat. Hasil pengabdian menunjukkan bahwa kegiatan pengabdian PPK memberikan dampak positif bagi mitra. Indikatornya terlihat pada adanya perubahan pemikiran dan sikap terkait dengan manajemen dan pengembangan usaha, antara lain Meningkatnya pengetahuan dan ketrampilan untuk dapat lebih kreatif dalam memasarkan produk sehingga dapat meningkatkan pendapatan mitra yang nantinya akan menjadi mitra yang mandiri, Meningkatnya pengetahuan dan pemahaman tentang Entrepreneural Marketing, Meningkatnya ketrampilan dan kreatifitas usaha dibidang kerajinan tangan dan pengolahan produk makanan berbasis potensi pertanian lokal, Meningkatnya kemampuan menyusun analisis usaha dan menetapkan strategi pengembangan usaha, dan Meningkatnya kesadaran pentingnya manajemen organisasi dan masyarakat.
Kata Kunci: Entrepreneural Marketing, Creativepreneur, Desa Pakis, Desa Sejahtera Mandiri
Ketersediaan dan Serapan Mg Kacang Tanah Alfisol dengan Abu Vulkanik Kelud dan Pupuk Organik Amandemen
Authors: Suntoro Suntoro , Widjianto Hery , Handayani Tutik 
Published: November 2019

<p>As a result of volcanic eruptions led to the fall of the ash, but there is no much research conducted against nutrient content and the nutrient availability in soil. Disposals of volcanic ash and organic matter are expected fill Mg need in the land. Magnesium In Alfisol is still sufficientless for peanuts. The purpose of this research is study of the impact of volcanic ash and organic fertilizer for the availability and uptake of peanuts Mg in the Alfisol. The experiments did in a greenhouse used completely randomized design with one factor. Data were analyzed with F test rate from 95%, and if the treatments showed significant influenced were continued with rate duncan's multiple range test fence from 95%. The observed variables include the levels of chlorophyll, available Mg and uptake Mg. Research results show that the interaction from treatment chlorophyll content, available Mg and uptake Mg. Based on the findings of the observations of volcanic ash disposals operating significantly impact the availability of magnesium.</p>
Penggunaan Limbah Baglog Tiram dan Jenis Nutrisi Terhadap Pakcoy Pada Hidroponik Substrat
Authors: Arni Putri Retno Bandriyati , Sulistyo Trijono Djoko , Anwar Chairul 
Published: November 2019

<p>The increase of oyster mushroom farmers in wonogiri will be impact immediately on increasing waste baglog. One of the utilization is to be medium on hydroponic substrate for growing mustard greens and it will combined with charcoal and various types of nutrients. The research was conducted from October to December 2015 at the Greenhouse C and Laboratory EMPT UNS.the research employed completely random design (CRD) with two factor that is ratio of medium and various types of nutrients. The result of research showed that interaction between ratio of medium and various types affected significantly the parameters of leaf area, leaf fresh weight and leaf biomass. Root fresh weight, root volume, root length and root biomass is only influenced by the type of nutrition with the ab mix is the most good in improving and supplying nutrients</p>
Dosis Pupuk NPK Terhadap Pertumbuhan dan Hasil Jagung Hibrida
Authors: Pusparini Pricillia Galuh , Yunus Ahmad , Harjoko Dwi 
Published: November 2019

<p>Corn is an important crop. Potency of corn productivity in Indonesia are still low. Main obstacles of increasing corn productivity is convertion of fertile land into non agriculture interest. the increase of corn productivity can be done by administrating NPK fertilizer and hybrid variety. This research is aiming at deciding and analyzing the effect of NPK fertilizer administration and hybrid corn variety towards growth and result. This research was held in June to October 2017, at Srimartani Village, Piyungan Districts, Bantul Regency, Daerah Istimewa Yogyakarta with regosol soil type and land altitude around 80 meter above sea surface. This experiment arranged in split plot design by factorial. Experimented factor are two corn hybrid variety ABCD and EFGH (main plot) with three doses of NPK fertilizer 200, 300 and 400 kg ha<sup>-1</sup> (sub plot). The result of research show that there are responds in two variety towards NPK fertilizer dosage almost same (unreal interraction). ABCD and EFGH variety reach highest result of height and component at 300 kg ha<sup>-1</sup>doses. Variable of cob weight with husk, cob weight without husk, cob length, total row, dry pipilan weight per plot, 100 seeds weight, fresh stover wieght, dry stover weight, harvest index and yield per hectare the highest average is variety of EFGH. NPK fertilizer dosage 300 kg ha<sup>-1</sup> is the best amount to optimally increase the growth and yield of hybird corn (8,92 ton ha<sup>-1</sup>). EFGH variety with 300 kg ha<sup>-1</sup> NPK fertilizer dosage can increase the potency of hybird corn yield. EFGH variety is showing better results (9,26 ton ha<sup>-1</sup>). </p>
Well-Leg Rhabdomyolysis After Prolonged Knee Arthroscopy
Authors: Reynolds Christopher , Johnson David B. , Triplet Jacob J. , Comisar B. Rodney 
Published: November 2019

Case:
We present the case of an obese patient who underwent combined arthroscopic and open multiligamentous knee reconstruction who, 3 months later, required revision arthroscopic anterior cruciate ligament and posterior cruciate ligament reconstruction with open lateral collateral ligament and posterolateral corner reconstruction lasting 6 hours 30 minutes. The patient developed rhabdomyolysis of the nonoperative leg after the revision procedure. Both procedures were performed in a hemilithotomy position with a commonly used leg positioner.

Conclusions:
Complications secondary to patient positioning are a source of unnecessary patient morbidity. Surgeons should be mindful of the nonoperative extremity, particularly during prolonged cases in obese patients. Prompt diagnosis and multidisciplinary treatment can lead to the resolution of symptoms without long-term sequelae.
Periprosthetic Humeral Fractures in Shoulder Arthroplasty
Authors: Fram Brianna , Elder Alexandra , Namdari Surena 
Published: November 2019

» The reported combined rates of intraoperative and postoperative periprosthetic humeral fractures range widely, from 1.2% to 19.4%.» The risk factors for an intraoperative humeral fracture and literature-reported strength of association include a press-fit humeral component (relative risk [RR], 2.9), revision arthroplasty (RR, 2.8), history of instability (odds ratio [OR], 2.65), female sex (OR, 4.19), and posttraumatic arthritis (RR, 1.9). The risk factors for a postoperative humeral fracture include osteonecrosis and increased medical comorbidity index (OR, 1.27).» Intraoperative fractures, in order of decreasing frequency, most often occur during implant removal in cases of revision arthroplasty (up to 81%), during reaming or broaching of the humerus (up to 31%), during trial or implant insertion (up to 18% to 19%), or because of excessive humeral torque or forceful retractor placement during exposure or reduction (up to 13% to 15%). Postoperative fractures typically occur from a fall onto the outstretched extremity or through an area of osteolysis.» The treatment of intraoperative or postoperative fractures is based on fracture location, prosthesis type and stability, rotator cuff status, and available bone stock.» Nonoperative treatment for periprosthetic humeral fractures appears to have high failure rates. When treating a periprosthetic humeral fracture operatively, surgical techniques for tuberosity fractures include suture repair, cerclage wiring, or revision to reverse components. For humeral shaft fractures, techniques include revision to a long-stem component, cerclage wiring, plate-and-screw fixation, and use of a strut allograft. For extensive humeral bone loss, techniques include component-allograft composites or humeral endoprostheses. All techniques have the goals of permitting early range of motion and preserving function.
SUSTAINABILITY OF SCHOOL-BASED FOOD AID IN BAHI DISTRICT OF TANZANIA’S DODOMA REGION AFTER THE END OF WORLD FOOD PROGRAMME SUPPORT
Authors: Nemes Joyce Exusper 
Published: November 2019

This study investigated the sustainability of school-based food drive after the phasing out of the World Food Programme (WFP) aid initiative in Bahi district of Dodoma region, Tanzania. The study found that none of the 72 public primary schools in Bahi district had managed to provide school lunch during the post-WFP by October 2017. Only 10 schools managed to provide porridge rather than full lunch to the pupils during the review period. The public primary schools under review were unable to sustain the School Food Programme due to the poor level of parental contributions, drought and widespread poverty. The study also found that parents complained about the school food programme lacking support within the national policy framework. The study recommends the application of the Resource Dependency Theory to sustain the SFP and government’s intervention to boost agricultural production and empower the people to support their wards and the SFP at their wards’ school.