bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of pre-sowing seed treatment on seedlings growth rate and their excretory activity
Authors: Bozhkov A. I. , Kovalova M. K. , Azeez Z. A. , Goltvjansky А. V. 
Published: May 2020

The importance of studying pre-sowing seed treatment lies in the possibility of regulating the rate of seed germination, the intensity of their growth and obtaining root exudates in biotechnology. The effect of three pre-sowing treatment methods was examined (control – washing with running water; the first method – washing with 0.05% sodium permanganate solution; the second method – 30 se­conds in 70% ethyl alcohol (C2H5OH) and 30 minutes in 5% sodium hypochlorite (NaOCl); the third method – 5 minutes in 70% C2H5OH and 40 minutes in 5% NaOCl) on the growth rate, germination rate, excretion rate of seeds of wheat and peas and composition (of protein, carbohydrate, amino acid content) of root exudates from the first to the third day of growth in order to obtain root exudates. It was revealed that the same pre-sowing treatment of wheat and pea seeds has a different effect on the rate and variability of seedling growth from the first to the third day, as well as on the qualitative and quantitative composition of root exudates. It was shown that pre-sowing treatment of wheat and pea seeds for 5 minutes with 70% ethanol followed by treatment with sodium hypochlorite (a “hard” treatment method) accelerates seedling growth and seed germination. This method of treatment reduces the intensity of excretion of root exudates and composition in wheat, but it increases the intensity of excretion in peas. The discovered effects can be explained by hormesis. Additionally, the third method of pre-sowing seed treatment can be used in root technologies for obtaining root exudates.
Influence of modern treatment regimens on serum biochemical parameters in piglets with gastroenteritis
Authors: Lukashchuk B. O. , Slivinska L. G. , Shcherbatyy A. R. , Zinko H. O. , Gutyj B. V. 
Published: May 2020

The article presents analyses of biochemical parameters of blood serum in weaned piglets with non-contagious gastroenteritis and after their treatment with a probiotic (live spores of Bacillus cereus var. toyoi; silicic acid; calcium carbonate) and a phytobiotic (natural extracts of Oreganum vulgare, Cinnamomun cassia and Capsicum annuum; hydrogenated rapeseed oil) as part of the basic ration in combination with antibiotic (10% solution of enrofloxacin hydrochloride) on a modern pig farm. In animals of the experimental groups with gastroenteritis we established hypoproteinemia, hypoalbuminemia, hypoglycemia, hypoureaemia, hypercreatininemia, hyperbilirubinemia and increase of enzyme activity compared to parameters of clinically healthy piglets. The study established that the use of probiotics and phytobiotics for weaned piglets had a positive influence on protein synthesis function of the liver, as indicated by the normalization of serum total protein and albumins. Also, we found a positive influence of probiotics and phytobiotics on intensity of protein metabolism, as indicated by an increase of serum urea to the level of clinically healthy piglets. Use of phytobiotics for piglets had a positive influence on the process of gluconeogenesis in their body, which is indicated by the normalization of serum glucose to the level of clinically healthy piglets. Also, the use of probiotics and phytobiotics had a positive influence on the pigment-forming function of the liver, as indicated by the reduction of serum total bilirubin to the level of clinically healthy piglets. The use of probiotics and phytobiotics reduced activity of serum alanine and aspartate aminotransferases in the piglets of the experimental groups, indicating the stabilization of hepatocytes’ cell structures (mitochondrial and cytosolic). The study established positive influence of probiotics and phytobiotics on the functioning of the liver and biliary tract, as indicated by decreased activity of serum alkaline phosphatase and gamaglutamiltranspeptidase to the level of clinically healthy piglets. So, addition of probiotics and phytobiotics to mixed fodder up to 45 days of age, normalizes functioning of the kidneys and liver in weaned piglets with gastroenteritis.
Effect of L-arginine and aminoguanidine on the cytokine profile in obstetric antiphospholipid syndrome
Authors: Yaremchuk O. Z. , Posokhova K. A. , Lykhatskyi P. H. , Letniak N. Y. , Moseychuk I. P. 
Published: May 2020

Antiphospholipid syndrome (APS) is one of the autoimmune causes of miscarriage in pregnancy. We researched the influence of L-arginine (25 mg/kg), the precursor of nitric oxide synthesis, and aminoguanidine, the inhibitor of inducible NO-synthase (10 mg/kg) on the concentration of IL-1β, IL-6, TNF-α, IL-4, IL-10 in serum of BALB/c mice on the 18th day of pregnancy in cases of APS. In the serum of the pregnant mice with APS, an increase in the concentration of proinflammatory cytokines (IL-1β, IL-6, TNF-α) and a decrease in the concentration of anti-inflammatory cytokines (IL-4 and IL-10) was evidenced, relative to those of the pregnant animals without APS. With the use of L-arginine, a decrease in the concentration of IL-1β, IL-6, TNF-α and an increase in the concentration of IL-4 and IL-10 was established, compared with the indicators of the pregnant mice with APS. The introduction of aminoguanidine, the selective inhibitor of iNOS, did not cause any changes in IL-1β, IL-6 and IL-10 compared with the group of animals with APS. However, a decrease in TNF-α concentration and an increase in IL-4 concentration were proved in this series compared with the group of pregnant animals with APS. Combined administration of L-arginine and aminoguanidine caused a decrease in the concentration of IL-1β, IL-6, TNF-α and an increase in the concentration of IL-4 and IL-10, compared with the indicators of the animals with APS. Thus, the combined administration of L-arginine and aminoguanidine to the pregnant mice with APS contributes to the rebalancing of proinflammatory and anti-inflammatory cytokines in the serum more than their individual use.
Tinjauan Hukum Islam terhadap Implikasi Fenomena Kawin Kontrak dalam Kehidupan Sosial, Ekonomi Masyarakat Desa
Authors: Arifin Muhamad Ramdan 
Published: May 2020

Fenomena kawin kontrak yang marak terjadi di kawasan Desa Tugu Selatan Cisarua Bogor, Keabsahan suatu perkawinan didasarkan pada pemenuhan rukun dan syarat perkawinan. Rukun perkawinan dibahas Kompilasi Hukum Islam,sedangkan syarat perkawinan dimuat dalam Kompilasi Hukum Islam dan Undang-Undang Nomor 1 tahun 1974 tentang Perkawinan. Dalam Hukum Islam dikenal nikah mut’ah, Keabsahan nikah mut’ah tersebut merupakan masalah khilafiyah antara Sunni dan Syiah sampai saat ini. Artikel ini untuk menganalisis pelaksanaan fenomena kawin kontrak serta faktor-faktor yang melatar belakanginya, dan juga menganalisis peranan tokoh masyarakat serta aparatur pemerintah dalam menanggulangi fenomena tersebut serta tinjauan hukum Islam terhadap implikasi fenomena kawin kontrak dalam kehidupan masyarakat baik secara sosial dan ekonomi yang dapat menimbulkan akibat hukum. Metode Pengumpulan data yang digunakan melalui pengumpulan dokumen, observasi dan wawancara Melalui pendekatan kualitatif. Akhirnya penelitian ini menemukan bahwa praktek kawin kontrak yang berlangsung tidak sesuai dengan ketentuan nikah mut’ah juga undang-undang perkawinan
Gerakan Dialog Keagamaan Jaringan Kerja Antar Umat Beragama (Jakatarub) Dan Kontribusinya Terhadap Kerukunan Hidup Umat Beragama
Authors: Wahyuni Dwi 
Published: May 2020

Merupakan penelitian mengenai gerakan dialog keagamaan Jaringan Kerja Antar Umat Beragama (JAKATARUB) dan kontribusinya terhadap kerukunan hidup umat beragama di Kota Bandung. Tujuan dari penelitian ini untuk menjelaskan strategi dan taktik yang dilakukan aktivis gerakan dialog keagamaan JAKATARUB, menganalisis faktor-faktor pendukung dan penghambat gerakan dialog keagamaan JAKATARUB dan mengetahui kontribusi gerakan dialog keagamaan JAKATARUB terhadap kerukunan hidup umat beragama di Kota Bandung. Menggunakan metode kualitatif, dengan teknik pengumpulan data secara observasi, wawancara, dokumentasi dan studi kepustakaan. Kerangka teori yang digunakan adalah teori mobilisasi sumberdaya dan teori proses framing. JAKATARUB dalam gerakan dialog keagamaannya ialah memperluas jaringan, mobilisasi sumberdaya dan merubah struktur organisasi. Selanjutnya strategi JAKATARUB, diturunkan kepada bagian-bagian kecil dari setiap langkah gerakan. Bagian-bagian tersebut ialah pelaksanaan program-program yang bekerja sama dengan mitra JAKATARUB dan menyampaikan makna dari isu-isu prioritas gerakan kepada kelompok sasaran. Pada pelaksanaan program-program dan penyampaian makna merupakan taktik dari gerakan dialog keagamaan JAKATARUB.
Significant Benefits of Osimertinib Against Adenosquamous Carcinoma Harboring Germline T790M Mutation
Authors: Huo Ran , Li Jinghua , Li Xiaofang , Shi Junping , Wang Kunjie , Jiao Jin , Shang Yanhong 
Published: May 2020

Abstract

Background
The identification of epidermal growth factor receptor (EGFR) mutations represents a milestone in the treatment of advanced non-small cell lung cancer. Patients with lung adenosquamous carcinomas (ASCs) rarely present with germline EGFR T790M mutation. The optimal treatment for cancers with germline EGFR T790M mutation (especially ASC) is not clear.

Materials and Methods
Using next-generation sequencing, we tested 450 cancer-related genes in a 27-year-old patient's lung adenosquamous carcinoma and matched blood samples. Germline mutations in samples from the patient's available relatives were identified by Sanger sequencing.

Results
We identified germline EGFR T790M mutation in the patient's lung adenosquamous carcinoma. He was treated with osimertinib and achieved complete response for more than 30 months, without significant drug-related adverse events. Genetic testing showed that germline EGFR T790M mutation might be a characteristic of inherited lung cancer.

Conclusion
Osimertinib can be a treatment option for patients with lung ASC harboring germline EGFR T790M mutation.

Key Points
A patient with adenosquamous carcinoma harboring a germline T790M mutation responded well to osimertinib with a progression-free survival of more than 30 months and without any unexpected toxicities. Osimertinib is effective for patients with lung squamous cell carcinoma with T790M and L858R mutations. The germline EGFR T790M mutation is associated with genetic susceptibility to lung cancer. The clinical use of next-generation sequencing could maximize the benefits of precision medicine in patients with cancer.
Basophil Count, Percentage of Basophil and Basophil Lymphocyte Ratio in Psychiatry Practice: Current Approaches and Future Directions
Authors: ORUM Mehmet Hamdi 
Published: May 2020

It is an easy and inexpensive method to
utilize hematologic parameters in cases where we cannot get clear information
from the patients. The basophils are definitely involved in immunopathologic
responses to parasites, and in this respect, there may be a relationship between parasitic
infections and developmental disorders. In this study, we discussed the possible uses of basophil and related parameters.
Evaluation Of Demographic Characteristics And Clinical Outcomes Of Patients Presenting To The Emergency Department With Suicide Attempt
Authors: ATİK Dilek , YALIMOL Nusin , BULUT Bensu , ERDUR Ahmet , KAYA Hilmi , UNAL Ramazan , GUVEN Ramazan , CANDER Basar 
Published: May 2020

Objectives:Suicide
is a state of aggression that is voluntarily directed towards the self. Suicide
cases with increasing mortality and morbidity rates with each passing day are
an important public health problem. In this study, it
was aimed to evaluate the demographic characteristics, methods of suicide
attempt with variable factors of clinical results of the patients who applied
with the reason of suicide attempt, and to contribute to literature with the
results. Methods:
This study was performed retrospectively by examining forensic records and
patient files of patients who came to a Training and Research Hospital
Emergency Medicine Clinic with the reason of suicide between the dates of
01.12.2018-31.12.2018. Chi-Square Independence,
Chi-Square Trend, and Fisher's Exact tests were used in statistical. p
&lt;0.05 was considered statistically significant.Results:
A total of 504 patients were included in our study.Among the participants,
70.4% were female and 29.6% were male.
The mean age of the participants was 30.14. Education levels were evaluated, 67.7%
were high school graduates, 22.4% university graduates, 8.1% middle school
graduates and 1.8% elementary school graduates.The
suicide attempt months between groups was not statistically significant in the
presence of psychiatric disorder Glaskow coma scale, final clinical results,
distribution of suicide attempt according to months and the time of suicide
attempt was found to be statistically significant .

Conclusion: The phenomenon of suicide is a situation that has not lost its
importance on the agenda both in our country and the world for centuries as one
of the causes of early death that can be prevented,unlike normal life
expectancy.We believe that individuals should be, in addition to check-ups
starting in primary school, periodically checked for mental health starting
from school age, and that possible suicide attempts can be prevented by working
together with psychological counselors starting from school age.
The Association of Potato Consumption and Psychological Disorders in Women: A Cross-Sectional Study
Authors: Darooghegi Mofrad Manije , Siassi Fereydoun , Guilani Bijan , Azadbakht Leila 
Published: May 2020

Background: Previous studies reported controversial findings regarding the association of potato consumption with the risk of chronic diseases. The purpose of this study was to determine the relationship of potato consumption with depression, anxiety, and stress in Tehrani women.
Methods: In this cross-sectional study, 488 women aged 20-50 years old who referred to health centers affiliated with Tehran University of Medical Sciences were selected by multistage cluster sampling. Their usual dietary intake in the past year was evaluated using a semi-quantitative food frequency questionnaire containing 168 items with confirmed validity and reliability. Psychological disorders were assessed using a validated Depression, Anxiety, and Stress Scales (DASS) questionnaires with 21-items. In the logistic regression analysis, the results were adjusted to the confounding factors.
Results: After adjustment of the confounding variables, consuming potatoes had no significant association with depression (P = 0.12), anxiety (P = 0.19), and stress (P = 0.63). Furthermore, consuming boiled potatoes had no significant association with depression (P = 0.59), anxiety (P = 0.19), and stress (P = 0.37). Intake of fried potatoes had no relationship with depression (P = 0.16), anxiety (P = 0.27), and stress (P = 0.97).
Conclusion: Potato consumption has no significant relationship with depression anxiety and stress in Tehrani women.
Prevalence of Congenital Anomalies in Newborns in Zabol: A Single Hospital Based Study
Authors: Jahantiq Mojtaba , Mazaheri Mahta , Rabaninia Tayebeh , Javaheri Atiyeh , Amjadi Nooshin 
Published: May 2020

Background: Congenital anomalies are conditions of prenatal origin that are present at birth, potentially impacting an infant's health, development and survival. The birth of a newborn with congenital anomalies imposes financial and emotional burdens on families. The aim of this study was to investigate the epidemiology of congenital anomalies in 2014 in Zabol, Iran.

Methods: This cross-sectional study was carried out in the Amir Al-Momenin Hospital between May of 2013 and April 2014. All the live born were included, and we have examined all newborns for the presence of congenital anomalies.

Results: During the twelve months, 9,309 newborns were included to the study. Of them, 72 (0.8%) newborns were affected with a congenital malformation. The congenital anomalies affected significantly higher proportion of male newborns (66.7%) than female newborns (33.3%). Among of them, musculoskeletal system abnormalities account for 45.9% of the total abnormalities allocating the highest frequency to itself. Subsequently, central nervous system abnormality (19.4%), gastrointestinal anomaly (15.3%), urinary tract abnormality (9.7%), chromosomal abnormality (2.8%), and multiple anomalies (1.4%) were frequent, respectively.

Conclusion: This study showed that prevalence of congenital anomalies is restively high in Zabol city. The results of this study identify the necessity of genetic counseling and early diagnosis to prevention, care and surveillance.
PRAGMATISM IN SAUDI-IRANIAN RELATIONS AND ITS IMPACT ON THE YEMENI CRISIS (2011-2019)
Authors: Alarqan Abdullah 
Published: May 2020

Purpose of the study: The study aimed at analyzing the pragmatic approaches of Saudi-Iranian relations and their impact on the Yemeni crisis (2011-2019).
Methodology: The study uses a combination of the used decision-making approach and the international system approach.
Main Findings: Saudi-Iranian relations were sometimes pragmatic because they were based on each country’s fulfillment of its national interests. This did not change the Saudi and Iranian strategy nor did it lead to loosening US domination over the Gulf region.
Applications of this study: This research can be used for academic purposes for universities, lecturers of political science, researchers, and undergraduate and postgraduate students. Also, it can be used for policy purposes for the decision-makers and politicians.
Novelty/Originality of this study: The phenomenon that existed in Saudi-Iranian relationships and referring to various previous research results, the study regarding the Saudi-Iranian relationship was conducted and presented comprehensively and completely. It is necessary to take into account this topic that can explore the Saudi-Iranian relationship and determine the extent to which topic can contribute to political science researches.
Obstacles of implementing educational techniques in special education centres from autism teachersâ€™ perspective
Authors: Sabayleh Obaid Abdelkrim , Alramamneh Abdullatif Khalaf 
Published: May 2020

This study aimed at identifying the obstacles of implementing learning technologies from the perspective of the teachers at autism centres in Amman. To achieve the objectives of the study, the researchers adopted a descriptive research method and used the survey as a tool of the study. The sample that was selected randomly consisted of 270 teachers from the autism centres in Amman. The study found that there were significant obstacles facing teachers at the autism centres in Amman in implementing learning technologies, the obstacle fields ranked as follows: learning technology, autism centre, autistic students and teachers, respectively. The study recommended: providing a special laboratory for learning technology resources room in centres, provide a special financial budget for autism centres and that the administrator of the autism centres must encourage the teachers to use learning technologies in teaching.
Keywords: Amman, autism teachers, implementation, learning technology, obstacles1.
Prediction of the time spent on Instagram by social media addiction and life satisfaction
Authors: Yesilyurt Ferahim , Solpuk Turhan Nihan 
Published: May 2020

There are many different debates regarding the time spent on Instagram by social media addiction and life satisfaction. In consequence, in this research, it is aimed to reveal the variables that predict the time spent on Instagram by university students. The research is done in accordance with the causal and correlation model by using a quantitative research method. The results of the research are predicted by the time spent on Instagram, gender, age and social media addiction. Time spent on Instagram differentiates in accordance with the level of social media addiction (Sig = 0.00, p < 0.05) but does not differentiate by life satisfaction (Sig = 0.06, p > 0.05). As social media addiction increases, life satisfaction decreases (r = âˆ’0.19). Women spent 0.42 times more time, and the women at the age of 21â€“22 years spent 0.38 times more time on Instagram.
Keywords: Instagram, life satisfaction, social media, addiction.
A comparative analysis of the 4th- and 5th-grade social studies curriculum according to revised bloom’s taxonomy
Authors: Koc E. Seda , Ontas Turgay 
Published: May 2020

This study, in which the distribution of the attainments of Turkey, Singapore, Hong Kong and Canada (Ontario) social studies curricula was aimed to be analysed according to the revised Bloomâ€™s taxonomy, was designed with qualitative research. A document analysis technique, which is one of the qualitative research data collection techniques, was used in the research. The data source of the research consisted of the social studies curricula of the mentioned countries, and the frequency and percentage calculation was used to show the taxonomic distributions of attainments. According to the findings obtained in the study, it was determined that the majority of the attainments in all of the social studies curricula examined in the study were commonly at the conceptual knowledge dimension and understand cognitive process. It was also found out that the social studies curriculum of Canada and Singapore was the curricula with the highest level of objectives for the higher levels.
Keywords: Social studies, curriculum, attainment, revised bloomâ€™s taxonomy.