bluuebunny/crossref_metadata_2025_split huggingface dataset:
Institutional variation in recovery after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: An opportunity for enhanced recovery pathways
Authors: Eng Oliver S. , Blakely Andrew M. , Lafaro Kelly J. , Fournier Keith F. , Fackche Nadege T. , Johnston Fabian M. , Dineen Sean , Powers Benjamin , Hendrix Ryan , Lambert Laura A. , Ronnekleiv‐Kelly Sean , Walle Kara Vande , Grotz Travis E. , Leiting Jennifer L. , Patel Sameer H. , Dhar Vikrom K. , Baumgartner Joel M. , Lowy Andrew M. , Clarke Callisia N. , Mogal Harveshp , Zaidi Mohammad Y. , Staley Charles A. , Kimbrough Charles , Cloyd Jordan M. , Lee Byrne , Raoof Mustafa 
Published: July 2020

AbstractBackgroundVariations in care have been demonstrated both within and among institutions in many clinical settings. By standardizing perioperative practices, Enhanced Recovery After Surgery (ERAS) pathways reduce variation in perioperative care. We sought to characterize the variation in cytoreductive surgery (CRS)/heated intraperitoneal chemotherapy (HIPEC) perioperative practices among experienced US medical centers.MethodsData from the US HIPEC Collaborative represents a retrospective multi‐institutional cohort study of CRS and CRS/HIPEC procedures performed from 12 major academic institutions. Patient characteristics and perioperative practices were reported and compared. Institutional variation was analyzed using hierarchical mixed‐effects linear (continuous outcomes) or logistic (binary outcomes) regression models.ResultsA total of 2372 operations were included. CRS/HIPEC was performed most commonly for appendiceal histologies (64.2%). The rate of complications (overall 56.3%, range: 31.8‐70.9) and readmissions (overall 20.6%, range: 8.9‐33.3) varied by institution (P < .001). Institution‐level variation in perioperative practice patterns existed among measured ERAS pathway process/outcomes (P < .001). The percentages of variation with each process/outcome measure attributable solely to institutional practices ranged from 0.6% to 66.6%.ConclusionsSignificant variation exists in the perioperative care of patients undergoing CRS/HIPEC at major US academic institutions. These findings provide a strong rationale for the investigation of best practices in CRS/HIPEC patients.
Kinetics of hydrogen peroxide decomposition catalyzed by Cu‐buserite over a well‐sealed and thermostated kinetics assembly
Authors: Feng Lili , Lu Shupei , Qi Lin , Fang Mingwei , Song Yiran 
Published: July 2020

AbstractHerein a well‐sealed and thermostated kinetics assembly is designed and built, which can run stirred at different reaction temperatures. With the reaction assembly above and the volumetric method together, the hydrogen peroxide (H2O2) decomposition reaction kinetics is systematically investigated under a variety of reaction conditions over a copper‐doped buserite‐type layer manganese oxide (referred to as Cu‐buserite) as a heterogeneous catalyst. The overall second‐order rate law is fitted out by the linear regression analysis, with the reaction orders with respect to both H2O2 and Cu‐buserite determined to each be equal to 1, and then explicitly explained by the proposed Michaelis‐Menten like mechanism. The apparent activation energy Ea is estimated as 33.5 ± 2.5 kJ mol−1.
Emotional and Personality Traits are Determinants of Activity Avoidance in Chronic Rhinosinusitis Patients
Authors: Epperson Madison V. , Phillips Katie M. , Speth Marlene M. , Caradonna David S. , Gray Stacey T. , Sedaghat Ahmad R. 
Published: July 2020

ObjectivesChronic rhinosinusitis (CRS), like other sinonasal diseases, may be associated with avoidance of daily activities. Our goal was to identify characteristics associated with avoidance of activities due to CRS.Materials and MethodsA total of 194 CRS patients were recruited. CRS symptom burden was assessed with the 22‐item Sinonasal Outcome Test (SNOT‐22). SNOT‐22 nasal, sleep, ear/facial discomfort and emotional/psychological subdomain scores were calculated. Depressed mood was assessed using the two‐item Patient Health Questionnaire (PHQ‐2). Personality traits including conscientiousness, neuroticism, agreeableness, openness, and extraversion were assessed using the Big Five Inventory‐10 (BFI‐10) questionnaire. As the primary outcome, participants rated how often in the prior week that they had avoided any activities in day‐to‐day life due to their nasal or sinus symptoms on a scale of “never,” “rarely,” “sometimes,” “often,” or “extremely often.” Ordinal regression models, with bootstrap validation, were used to identify associations between activity avoidance and participants' characteristics.ResultsOn multivariable analysis, SNOT‐22 score (odds ratio [OR] = 1.03, 95% CI, 1.01–1.04, P = .026), and conscientiousness personality trait (OR = 1.38, 95% CI, 1.05–1.81, P = .019) were positively associated with activity avoidance while age (OR = 0.98, 95% CI, 0.96–0.99, P = .049) was negatively associated with activity avoidance. Of CRS symptom burden/SNOT‐22 subdomains, only the emotional/psychological subdomain score (OR = 1.28, 95% CI, 1.12–1.46, P < .001) was associated with activity avoidance.ConclusionYounger age and the conscientiousness personality trait were associated with activity avoidance in CRS patients. Of CRS‐associated symptomatology, sadness and embarrassment were associated with activity avoidance. Emotional traits and personality most strongly predict avoidance of activities in CRS patients.Level of Evidence2c. Laryngoscope, 131:707–712, 2021
Bilayer Cylindrical Conduit Consisting of Electrospun Polycaprolactone Nanofibers and DSC Cross‐Linked Sodium Alginate Hydrogel to Bridge Peripheral Nerve Gaps
Authors: Askarzadeh Neshat , Nazarpak Masoumeh Haghbin , Mansoori Korosh , Farokhi Mehdi , Gholami Mahdi , Mohammadi Javad , Mottaghitalab Fatemeh 
Published: July 2020

AbstractHerein, a bilayer cylindrical conduit (P‐CA) is presented consisting of electrospun polycaprolactone (PCL) nanofibers and sodium alginate hydrogel covalently cross‐linked with N,N′‐disuccinimidyl carbonate (DSC). The bilayer P‐CA conduit is developed by combining the electrospinning and outer–inner layer methods. Using DSC, as a covalent crosslinker, increases the degradation time of the sodium alginate hydrogel up to 2 months. The swelling ratio of the hydrogel is also 503% during the first 8 h. The DSC cross‐linked sodium alginate in the inner layer of the conduit promotes the adhesion and proliferation of nerve cells, while the electrospun PCL nanofibers in the outer layer provide maximum tensile strength of the conduit during surgery. P‐CA conduit promotes the migration of Schwann cells along the axon in a rat model based on functional and histological evidences. In conclusion, P‐CA conduit will be a promising construct for repairing sciatic nerves in a rat model.
Uncertainty reduction in quantitative precipitation prediction by tuning of Kain–Fritch scheme input parameters in the WRF model using the simulated annealing optimization method
Authors: Afshar Mohaddeseh A. , Azadi Majid , Rezazadeh Maryam 
Published: July 2020

AbstractIn the study, using the simulated annealing (SA) optimization method, tried to reduce the uncertainty of the prediction of the Weather Research and Forecasting (WRF) numerical model in convective rainfall forecasts. To this end, three parameters Pd, Pe and Ph in Kain–Fritch convective scheme that's related to downdraft mass flux, entrainment mass flux and starting height of downdraft above updraft source layer, respectively, are optimized using SA algorithm to achieve better values. Two nested domain were used in the study with 30 and 10 km resolution which inner domain cover southern coasts of the Caspian Sea for the study area. Runtime of the model was 36 hr with the first 12 hr spin‐up time. Study period selected October 12, 2012 for training algorithm and October 8, 2015 for test run. After 100 iteration of the algorithm, 1, 1 and 50 was obtained for Pd, Pe and Ph respectively, while default values of these parameters was 0, 0, and 150. Results show that in both cases, model with default values underestimates rainfall amount and after optimization, model performance improves. Also, spatial distribution of the model precipitation forecast was less than observations and after optimization, spatial distribution improves. Statistical analysis of results indicated Mean Bias (MB) and root mean square error (RMSE) in training case were −4.6 and 17.1 in model with default values and became −3.7 and 14.3 in optimized one, respectively. Also, MB and RMSE for test case increased to −8.4 and 23.8, respectively, in model result with optimized parameters from −10.6 to 29.4 in model with default parameters.
Finite time collapse in chemotaxis systems with logistic‐type superlinear source
Authors: Marras Monica , Vernier‐Piro Stella 
Published: July 2020

We consider the following quasilinear Keller–Segel system

on a ball
, n ≥ 3, R>0, under homogeneous Neumann boundary conditions and nonnegative initial data. The source term g(u) is superlinear and of logistic type, that is, g(u)=λu−μuk,k>1,μ>0, λ>0, and Tmax is the blow‐up time. The solution (u,v) may or may not blow‐up in finite time. Under suitable conditions on data, we prove that the function u, which blows up in L∞(Ω)‐norm, blows up also in Lp(Ω)‐norm for some p>1. Moreover, a lower bound of the lifespan (or blow‐up time when it is finite) Tmax is derived.In addition, if
a lower bound of Tmax is explicitly computable.
A database of 40 patient‐based computational models for benchmarking organ dose estimates in CT
Authors: Samei Ehsan , Ria Francesco , Tian Xiaoyu , Segars Paul W. 
Published: July 2020

PurposePatient radiation burden in computed tomography (CT) can best be characterized through risk estimates derived from organ doses. Organ doses can be estimated by Monte Carlo simulations of the CT procedures on computational phantoms assumed to emulate the patients. However, the results are subject to uncertainties related to how accurately the patient and CT procedure are modeled. Different methods can lead to different results. This paper, based on decades of organ dosimetry research, offers a database of CT scans, scan specifics, and organ doses computed using a validated Monte Carlo simulation of each patient and acquisition. It is aimed that the database can serve as means to benchmark different organ dose estimation methods against a benchmark dataset.Acquisition and validation methodsOrgan doses were estimated for 40 adult patients (22 male, 18 female) who underwent chest and abdominopelvic CT examinations. Patient‐based computational models were created for each patient including 26 organs for female and 25 organs for male cases. A Monte Carlo code, previously validated experimentally, was applied to calculate organ doses under constant and two modulated tube current conditions.Data format and usage notesThe generated database reports organ dose values for chest and abdominopelvic examinations per patient and imaging condition. Patient information and images and scan specifications (energy spectrum, bowtie filter specification, and tube current profiles) are provided. The database is available at publicly accessible digital repositories.Potential applicationsConsistency in patient risk estimation, and associated justification and optimization requires accuracy and consistency in organ dose estimation. The database provided in this paper is a helpful tool to benchmark different organ dose estimation methodologies to facilitate comparisons, assess uncertainties, and improve risk assessment of CT scans based on organ dose.
Characterization of stereoisomeric 5‐(2‐nitro‐1‐phenylethyl)furan‐2(5H)‐ones by computation of 1H and 13C NMR chemical shifts and electronic circular dichroism spectra
Authors: Lopes Dayane T. , Hoye Thomas R. , Alvarenga Elson S. 
Published: July 2020

AbstractIn the present work, we describe the preparation of two diastereomers from the enantioselective Michael addition of furan‐2(5H)‐one to (E)‐(2‐nitrovinyl)benzene catalyzed by a dinuclear Zn‐complex. The relative configurations of the diastereomeric products were assigned by comparing nuclear magnetic resonance (NMR) experimental chemical shift data with those computed by density functional theory (DFT) methods. Corrected mean absolute error (CMAE) and CP3 analyses were used to compare the data sets. The absolute configuration of each diastereomer was initially assigned by analysis of electronic circular dichroism (ECD) data, which was consistent with that of the known X‐ray crystallographic structure of the product of a related reaction, namely, (R)‐5‐((R)‐1‐(4‐chlorophenyl)‐2‐nitroethyl)furan‐2(5H)‐one.
Fast whole brain MR imaging of dynamic susceptibility contrast changes in the cerebrospinal fluid (cDSC MRI)
Authors: Cao Di , Kang Ningdong , Pillai Jay J. , Miao Xinyuan , Paez Adrian , Xu Xiang , Xu Jiadi , Li Xu , Qin Qin , Van Zijl Peter C. M. , Barker Peter , Hua Jun 
Published: July 2020

PurposeThe circulation of cerebrospinal fluid (CSF) is closely associated with many aspects of brain physiology. When gadolinium(Gd)‐based contrast is administered intravenously, pre‐ and post‐contrast MR signal changes can often be observed in the CSF at certain locations within the intra‐cranial space, mainly due to the lack of a blood‐brain barrier in the dural blood vessels. This study aims to develop and systemically optimize MRI sequences that can detect dynamic signal changes in the CSF after Gd administration with a sub‐millimeter spatial resolution, a temporal resolution of <10 s, and whole brain coverage.MethodsBloch simulations were performed to determine optimal imaging parameters for maximum CSF contrast before and after Gd injection. Simulations were validated with phantom scans. An optimized turbo‐spin‐echo (TSE) sequence was performed on healthy volunteers on 3T and 7T.ResultsSimulation results agreed well with phantom scans. In human scans, dynamic signal changes after Gd injection in the CSF were detected at several locations where cerebral lymphatic vessels were identified in previous studies. The concentration of Gd in CSF in these regions was estimated to be approximately 0.2 mmol/L.ConclusionDynamic signal changes induced by the distribution of Gd in the CSF can be detected in healthy human subjects with an optimized TSE sequence. The proposed methodology does not rely on any particular theory on CSF circulation. We expect it to be useful for studies on CSF circulation and cerebral lymphatic vessels in the brain.
Anthropometric indicators as predictors of pelvic floor muscle distress in young women
Authors: Scarabelot Karoline S. , da Silva Pereira Franciele , Pelegrini Andreia , Tuon Talita , Virtuoso Janeisa F. 
Published: July 2020

AbstractAimTo identify anthropometric indicators that could predict pelvic floor muscle distress (PFMD) in young women.MethodA cross‐sectional study was conducted, whose sample consisted of 54 women aged between 18 and 35 years. The Pelvic Floor Distress Inventory was used to assess the PFMD. The anthropometric indicators evaluated were body mass index (BMI) being measured the weight and height, body fat percentage (skinfolds), waist circumference (WC), waist‐to‐hip ratio (WHR), and relative fat mass (RFM), which is calculated from height and WC. Descriptive and inferential statistics (Spearman correlation, simple linear regression, and receiver operating characteristic curve) were used, with a significance level of 5%.ResultsThe PFMD and the anthropometric indicators BMI (r = .43), body fat percentage (r = .42), WC (r = .46), WHR (r = .49), and RFM (r = .48) showed a positive and moderate correlation (P < .01). In all, 24%, 23%, 20%, and 18% of the PFMD can be credited to RFM, WC, WHR, and body fat percentage, respectively. The cut‐off point for RFM was 38.44 for the symptom of pressure in the lower abdomen and 36.24 for symptom of stress urinary incontinence and incomplete emptying of the bladder.ConclusionAnthropometric indicators of body fat percentage, WC, WHR, and RFM can be predictors of PFMD in young women minimally symptomatic.
A scaled boundary finite element based explicit topology optimization approach for three‐dimensional structures
Authors: Zhang Weisheng , Xiao Zhe , Liu Chang , Mei Yue , Youn Sung‐kie , Guo Xu 
Published: July 2020

SummaryThis article proposes an efficient approach for solving three‐dimensional (3D) topology optimization problem. In this approach, the number of design variables in optimization as well as the number of degrees of freedom in structural response analysis can be reduced significantly. This is accomplished through the use of scaled boundary finite element method (SBFEM) for structural analysis under the moving morphable component (MMC)‐based topology optimization framework. In the proposed method, accurate response analysis in the boundary region dictates the accuracy of the entire analysis. In this regard, an adaptive refinement scheme is developed where the refined mesh is only used in the boundary region while relating coarse mesh is used away from the boundary. Numerical examples demonstrate that the computational efficiency of 3D topology optimization can be improved effectively by the proposed approach.
Quality of care and job satisfaction in a Hospital Trust before and after The Coordination Reform in Norway
Authors: Andersen Irene Aasen , Kleiven Ole T. , Kyte Lars , Pettersen Marny Alice Solhaug 
Published: July 2020

AbstractAimsTo study the impact of organizational changes on the quality of health services and on health professionals' job satisfaction in specialist health services.DesignA repeated cross‐sectional study, including 5 years before (2007) and 5 years after (2017) the introduction of The Coordination Reform in Norway.MethodsNurses and auxiliary nurses working in medical wards at three hospitals evaluated the quality of health services and various aspects of their working conditions, using questionnaires: Quality of Patient Care and the Job Satisfaction Scale.ResultsIn 2017, nurses and auxiliary nurses had longer work experience compared with 2007. Nurses and auxiliary nurses also worked full hours. There was no significant change over time in total Quality of Patient Care score or in any of the sub‐scores. There was no significant change in total Job Satisfaction Scale score over time, but there was a significant decline in the sub‐score for physical working conditions.
Usefulness of heart rate variability indices in assessing the risk of an unsuccessful return to work after sick leave in depressed patients
Authors: Shinba Toshikazu , Murotsu Keizo , Usui Yosuke , Andow Yoshinori , Terada Hiroshi , Takahashi Mami , Takii Rie , Urita Michiko , Sakuragawa Satoshi , Mochizuki Miwa , Kariya Nobutoshi , Matsuda Saori , Obara Yusuke , Matsuda Hanae , Tatebayashi Yoshitaka , Matsuda Yoshiki , Mugishima Go , Nedachi Takaki , Sun Guanghao , Inoue Tomoko , Matsui Takemi 
Published: July 2020

AbstractAimThe present study aimed to examine whether heart rate variability (HRV) indices in depressed patients measured at return to work after sick leave are related to the outcome of reinstatement.MethodsThis study included 30 workers who took a leave of absence due to major depressive disorder. HRV was measured twice, once when participants left work and another when they returned to work. One month after returning to work, 19 participants continued their original work (successful return group), while 11 failed to perform their original work (unsuccessful return group). HRV indices including high‐ and low‐frequency components (HF and LF) were calculated in three conditions within a session lasting for about 5 minutes, initial rest (Rest), mental task (Task), and rest after task (After), and were compared between the two participant groups. Psychological states were evaluated using Self‐rating Depression Scale and State‐Trait Anxiety Inventory.ResultsNo significant differences were observed in the HRV indices on leaving work between groups. On returning to work, the “unsuccessful return group” exhibited lower HF Rest score, higher HF Task/Rest ratio, and higher LF/HF Rest score than the “successful return group.” Psychological scores improved in both groups.ConclusionThese results indicate that autonomic dysregulations revealed by HRV measurement at return to work after a leave of absence in MDD patients were related to the outcome of reinstatement and can serve as useful information for the assessment of the risk of unsuccessful return.
Middle school students' preferences for praise
Authors: Schneider Maryia M. , Hulac David M. , Mickelson Lisa R. , Phillips Emily K. 
Published: July 2020

AbstractPraise, defined as public or private expression of approval for behavior, is recognized as a critical component in many classroom behavior interventions. Historically, praise has been viewed from the perspective of educators in terms of both increasing educator‐preferred behaviors and in terms of educators' perspectives. Little is known about students' perceptions of praise, particularly middle school students in the United States. The current study explored ways middle school students preferred to be praised and the behaviors students believed warranted praise. This included whether middle school students preferred praise to be delivered for effort or ability, and quietly or loudly. Using the Preference for Teacher Praise scale (PTP), 511 students were surveyed from an ethnically diverse middle school in the western half of the United States. Additional analysis investigated preferences based on age/grade, gender, and ethnicity. Results indicated that most students preferred to receive praise sometimes or almost always for both academic success and socially expected behaviors. However, most students preferred praise to be delivered quietly and to be focused on effort rather than ability. While girls were significantly more likely than boys to prefer effort praise to ability praise, all students preferred effort praise regardless of gender.
Stereotype threat is linked to language achievement and domain identification in young males: Working memory and intellectual helplessness as mediators
Authors: Bedyńska Sylwia , Krejtz Izabela , Rycielski Piotr , Sedek Grzegorz 
Published: July 2020

AbstractIn the present paper, we investigated the link between stereotype threat, school achievement, and domain identification in language arts. We hypothesized that stereotype threat may lead to higher intellectual helplessness, lower working memory capacity, lower achievement, and domain identification but only in young men highly identified with their gender group. To test these assumptions we used self‐descriptive measures of stereotype threat, intellectual helplessness, gender identification, and domain identification. We also evaluated working memory capacity by working memory test and school achievement using grade point average. Our predictions were tested in structural equation modeling on a nationwide sample of 319 young men from coeducational schools, aged 14–16 years. The results revealed that working memory was a mediator of achievement (γ = 0.45, 95% confidence interval [CI] = [0.34, 0.55]), while intellectual helplessness was related to both domain identification (γ = −0.13, 95% CI = [−0.22, −0.04]) and achievement (γ = −0.13, 95% CI = [−0.21, −0.06]). The proposed model extends our previous work on the role of intellectual helplessness in mathematics by testing the same intervening variable in a different domain, that is, in language arts. We discuss these results in light of previous research on stereotype threat and present practical implications.