bluuebunny/crossref_metadata_2025_split huggingface dataset:
La prohibición de Ébano swing y Cachita en el primer franquismo (Circular 98): mucho más que la simple censura de dos temas musicales
Authors: Centenera Sanchez Seco Fernando 
Published: January 2020

RESUMEN. Este trabajo centra la atención en la Circular 98, que prohibió los temas musicales Ébano swing y Cachita durante el primer franquismo. El estudio analiza la medida desde la perspectiva del totalitarismo, considera las causas que suscitaron la fijación de la censura en los dos temas citados, y los motivos que pudieran explicar circunstancias tales como la no proliferación de prohibiciones en el mismo sentido. También se tratan numerosas deficiencias normativas, tanto de la Circular 98 como de otras regulaciones dedicadas a la censura musical, así como la eficacia de la prohibición. Finalmente se exponen varias conclusiones.

ABSTRACT. This article focuses on the 98th Circular which banned the musical numbers Ébano swing and Cachita in the early years of the Franco regime. It analyses the measure from the perspective of totalitarianism and ponders what led the censor to prohibit both numbers and why such prohibitions did not proliferate. It also studies a number of regulatory shortcomings in the 98th Circular itself and in other legislation concerning the censorship of music, as well as assessing the efficacy of prohibition. Some conclusions bring the article to an end.
Feasibility of assessing ultra-short-term pulse rate variability from video recordings
Authors: Finžgar Miha , Podržaj Primož 
Published: January 2020

Objectives
Remote photoplethysmography (rPPG) is a promising non-contact measurement technique for assessing numerous physiological parameters: pulse rate, pulse rate variability (PRV), respiratory rate, pulse wave velocity, blood saturation, blood pressure, etc. To justify its use in ultra-short-term (UST) PRV analysis, which is of great benefit for several healthcare applications, the agreement between rPPG- and PPG-derived UST-PRV metrics was studied.

Approach
Three time-domain metrics—standard deviation of normal-to-normal (NN) intervals (SDNN), root mean square of successive NN interval differences (RMSSD), and the percentage of adjacent NN intervals that differ from each other by more than 50 ms (pNN50)—were extracted from 56 video recordings in a publicly available data set. The selected metrics were calculated on the basis of three groups of 10 s recordings and their average, two groups of 30 s recordings and their average, and a group of 60 s recordings taken from the full-length recordings and then compared with metrics derived from the corresponding reference (PPG) pulse waveform signals by using correlation and effect size parameters, and Bland–Altman plots.

Main results
The results show there is stronger agreement as the recording length increases for SDNN and RMSSD, yet there is no significant change for pNN50. The agreement parameters reach r = 0.841 (p < 0.001), r = 0.529 (p < 0.001), and r = 0.657 (p < 0.001), estimated median bias −1.52, −2.28 ms and −1.95% and a small effect size for SDNN, RMSSD, and pNN50 derived from the 60 s recordings, respectively.

Significance
Remote photoplethysmography-derived UST-PRV metrics manage to capture UST-PRV metrics derived from reference (PPG) recordings well. This feature is highly desirable in numerous applications for the assessment of one’s health and well-being. In future research, the validity of rPPG-derived UST-PRV metrics compared to the gold standard electrocardiography recordings is to be assessed.
Malaria Preventive Practices among Pregnant Women in Akwa Ibom State, Southern Nigeria
Authors: Kasso T. , Oboro I. L. , Maduka O. , Awopeju A. T. O. , Paul N. I. , Yaguo-Ide L. E. , Chijioke-Nwauche I. N. , Ogoro M. , Otto G. , Nwauche C. A. 
Published: January 2020

Background: Malaria is a serious public health problem in developing countries with Africa bearing most of its burden. Pregnant women are more susceptible to malaria and it is one of the leading causes of maternal and perinatal mortality/morbidity. Use of effective malaria preventive measures during pregnancy reduces its burden and complications.
Aim: This was to determine malaria preventive practices used by pregnant women in Akwa Ibom state, Nigeria.
Materials and Methods: It was a cross sectional study of pregnant women attending public and private health facilities in Akwa Ibom state. An informed written consent was obtained from the participants. Stratified sampling method was used in selecting the health facilities and the study participants. Information was obtained with pretested questionnaires by trained personnel with the aid of Open Data Kit (ODK) on android phones. Data was managed with SPSS 22.0 and P-value of <0.05 was considered statistically significant.
Results: There were 935 participants in the study. Their mean age was 28.52 ± 5.09 years with 879 (94.0%) being married. Most had secondary and tertiary degrees: 451(48.2%) and 440(47.1%). Majority of them were traders/business women and self-employed (58.2%) while 7% were unemployed. Malaria preventive practices were use of window net, bed net and insecticides accounting for 659(71%), 447(48.2%) and 207(22.3%) respectively. There were 612 (65.5%) participants that received malaria drugs for prevention with 452(73.9%) receiving Intermittent Preventive Treatment in Pregnancy (IPTp) with Sulfadoxine-Pyrimethamine (SP). Only 296 (31.7%) of them slept under bed nets the night before the interview.
Conclusion: Common preventive practices employed by pregnant women were IPTp with SP, window nets, ITNs and modified IRS. Majority of the women utilized widow nets, though not as effective as ITNs. Efforts should be intensified concerning awareness creation about the benefits of ITN use during pregnancy.
Additive Trees
Authors: Corter James E. 
Published: January 2020

Abstract
Additive trees are models for the analysis of proximity data. In such analyses, the data dissimilarities are represented by path‐length distances in the additive tree graph. The additive tree may be characterized as a weighted acyclic graph, in which the weights correspond to the arc lengths. An additive tree may be displayed in rooted or unrooted form. The choice of a root for an additive tree can affect its interpretation in terms of clusters. A number of effective heuristic algorithms have been developed for least‐squares fitting of additive trees to proximities.
TheJITAICode: A Primer on Just‐In‐Time‐Adaptive Interventions
Authors: El‐Toukhy Sherine , Nahum‐Shani Inbal 
Published: January 2020

AbstractThis chapter is a primer on just‐in‐time adaptive interventions (JITAIs), an intervention design concerned with using ongoing information about the individual and her environment to inform the effective and timely delivery of treatment. JITAIs are motivated by the necessity of intervening on risk and/or protective factors that occur frequently and unpredictably in one's natural environment. JITAIs' goal of providing the right treatment whenever and wherever needed is made possible by recent advances in mobile and wearable technologies. The goal of this chapter is to provide a brief introduction to JITAIs. This includes discussing the motivation underlying this intervention design, highlighting its key elements, and discussing opportunities and challenges relating to the construction of empirically based JITAIs. Throughout, we refer readers to additional reading for in‐depth discussion of these topics.
Metropolis Jumping Rules
Authors: Liu Jun S. , Dai Chenguang 
Published: January 2020

Abstract
We review the cornerstone of the Markov chain Monte Carlo methods, the Metropolis jumping rules, upon which we can generate samples to approximate an arbitrary target distribution known up to a normalizing constant. After introducing the basics of the Metropolis jumping rule along with the Hastings generalization, we describe three widely used proposal functions for constructing the rule. The reversible jumping rule is then introduced to serve as a general principle to guide the chain jumping across spaces with different dimensionalities. Based on these building blocks, we discuss three more delicate jumping rules, the multiple‐try Metropolis, dynamic weighting, and the Wang–Landau algorithm.
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee
Authors: Kolasinski Sharon L. , Neogi Tuhina , Hochberg Marc C. , Oatis Carol , Guyatt Gordon , Block Joel , Callahan Leigh , Copenhaver Cindy , Dodge Carole , Felson David , Gellar Kathleen , Harvey William F. , Hawker Gillian , Herzig Edward , Kwoh C. Kent , Nelson Amanda E. , Samuels Jonathan , Scanzello Carla , White Daniel , Wise Barton , Altman Roy D. , DiRenzo Dana , Fontanarosa Joann , Giradi Gina , Ishimori Mariko , Misra Devyani , Shah Amit Aakash , Shmagel Anna K. , Thoma Louise M. , Turgunbaev Marat , Turner Amy S. , Reston James 
Published: January 2020

ObjectiveTo develop an evidence‐based guideline for the comprehensive management of osteoarthritis (OA) as a collaboration between the American College of Rheumatology (ACR) and the Arthritis Foundation, updating the 2012 ACR recommendations for the management of hand, hip, and knee OA.MethodsWe identified clinically relevant population, intervention, comparator, outcomes questions and critical outcomes in OA. A Literature Review Team performed a systematic literature review to summarize evidence supporting the benefits and harms of available educational, behavioral, psychosocial, physical, mind‐body, and pharmacologic therapies for OA. Grading of Recommendations Assessment, Development and Evaluation methodology was used to rate the quality of the evidence. A Voting Panel, including rheumatologists, an internist, physical and occupational therapists, and patients, achieved consensus on the recommendations.ResultsBased on the available evidence, either strong or conditional recommendations were made for or against the approaches evaluated. Strong recommendations were made for exercise, weight loss in patients with knee and/or hip OA who are overweight or obese, self‐efficacy and self‐management programs, tai chi, cane use, hand orthoses for first carpometacarpal (CMC) joint OA, tibiofemoral bracing for tibiofemoral knee OA, topical nonsteroidal antiinflammatory drugs (NSAIDs) for knee OA, oral NSAIDs, and intraarticular glucocorticoid injections for knee OA. Conditional recommendations were made for balance exercises, yoga, cognitive behavioral therapy, kinesiotaping for first CMC OA, orthoses for hand joints other than the first CMC joint, patellofemoral bracing for patellofemoral knee OA, acupuncture, thermal modalities, radiofrequency ablation for knee OA, topical NSAIDs, intraarticular steroid injections and chondroitin sulfate for hand OA, topical capsaicin for knee OA, acetaminophen, duloxetine, and tramadol.ConclusionThis guideline provides direction for clinicians and patients making treatment decisions for the management of OA. Clinicians and patients should engage in shared decision‐making that accounts for patients’ values, preferences, and comorbidities. These recommendations should not be used to limit or deny access to therapies.
Modified cassava starch/poly(vinyl alcohol) blend films plasticized by glycerol: Structure and properties
Authors: Boonsuk Phetdaphat , Sukolrat Apinya , Kaewtatip Kaewta , Chantarak Sirinya , Kelarakis Antonios , Chaibundit Chiraphon 
Published: January 2020

ABSTRACTWe report a systematic investigation on the structure–property relationships in glycerol‐plasticized poly(vinyl alcohol) (PVA)/cassava starch blends prepared via solution casting. In particular, PVA mixed with native, low‐oxidized, high‐oxidized, and pregelatinized cassava starches were characterized by means of SEM, XRD, FTIR, thermal analysis and mechanical testing and the immiscible systems were received. Burial tests over a period of several days suggested the preferential degradation of the starch and glycerol component (as indicated by the absence of FTIR signatures of those components) and the amorphous phase of PVA (as indicated by the enhanced crystallinity index of the degraded samples). The rheological properties of the blends seem to dictate their morphological characteristics that, in turn, have a profound impact on their mechanical properties. In that sense, the study highlights promising strategies for the development of a new family of polymeric materials that combine their biodegradable nature within superior mechanical properties. © 2020 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48848.
A New Way to Discover IRESs in Pathology or Stress Conditions? Harnessing Latest High‐Throughput Technologies
Authors: Wang Lei‐Yun , Cui Jia‐Jia , Guo Cheng‐Xian , Yin Ji‐Ye 
Published: January 2020

AbstractThe cellular internal ribosomal entry site (IRES) is one of the most important elements to mediate cap‐independent translational initiation, especially under conditions of stress and pathology. However, a high‐throughput method to discover IRESs in these conditions is still lacking. Here, a possible way IRES long‐read sequencing based on the latest high‐throughput technologies is proposed to solve this problem. Based on this design, diversity and integrity of the transcriptome from original samples can be kept. The micro‐environment that stimulates or inhibits IRES activity can also be mimicked. By using long read‐length sequencing technology, additional experiments that are essential for ruling out the cryptic promoters or splicing events in routine IRES identification processes can be circumvented. It is hoped that this proposed methodology may be adopted for IRES element discovery, hence uncovering the full extent of the role of IRESs in disease, development, and stress. Also see the video abstract here https://youtu.be/JuWBbMzWXS8
Interactions among variants in P53 apoptotic pathway genes are associated with neurologic deterioration and functional outcome after acute ischemic stroke
Authors: Yi Xingyang , Zhou Qiang , Sui Guo , Ren Gaoping , Tan Lili , Li Jie , Lin Jing , Bao Shaozhi 
Published: January 2020

AbstractObjectiveNeurologic deterioration (ND) and functional outcome after ischemic stroke (IS) are not accurately predicted by clinical pictures on admission. The aim of present study was to investigate the association of variants in P53 apoptotic pathway genes with ND and functional outcome after IS.MethodsGenotypes of nine variants in apoptosis‐relevant genes were measured in patients with acute IS. Gene–gene interactions were analyzed by generalized multifactor dimensionality reduction (GMDR). The primary outcome was ND. ND was diagnosed in patients who worsened ≥2 points (National Institutes of Health Stroke Scale [NIHSS] score) within the first 10 days of stroke onset. The secondary outcome was functional status at 90 days after IS as measured by modified Rankin Scale (mRS) score.ResultsA total of 705 enrolled patients, ND occurred in 174 (24.7%) patients, and 184 (26.1%) patients were poor functional outcome (mRS score > 2). Although the nine variants were not significantly associated with ND and functional outcome by univariate analysis, there was a gene–gene interaction among P53rs1042522, MDM‐2rs2279744, and MMP‐9 rs3918242 using GMDR analysis. The high‐risk interaction among the three variants was independently associated with higher risk of ND (HR, 2.04, 95% CI: 1.22–5.64, p = .018) and poor functional outcome (OR, 2.68, 95% CI: 1.68–7.86, p = .004) after adjusting for the covariates.ConclusionThe interactions among P53 rs1042522, MDM‐2 rs2279744, and MMP‐9 rs3918242 may increase the risk of ND and poor functional outcome and may be considered as a genetic marker of predicting ND and poor functional outcome after stroke.
Tyrosine nitration as a key event of signal transduction that regulates functional state of the cell
Authors: Sabadashka Mariya , Nagalievska Mariia , Sybirna Nataliia 
Published: January 2020

AbstractThis review is dedicated to the role of nitration of proteins by tyrosine residues in physiological and pathological conditions. First of all, we analyze the biochemical evidence of peroxynitrite formation and reactions that lead to its formation, types of posttranslational modifications (PTMs) induced by reactive nitrogen species, as well as three biological pathways of tyrosine nitration. Then, we describe two possible mechanisms of protein nitration that are involved in intracellular signal transduction, as well as its interconnection with phosphorylation/dephosphorylation of tyrosine. Next part of the review is dedicated to the role of proteins nitration in different pathological conditions. In this section, special attention is devoted to the role of nitration in changes of functional properties of actin—protein that undergoes PTMs both in normal and pathological conditions. Overall, this review is devoted to the main features of protein nitration by tyrosine residue and the role of this process in intracellular signal transduction in basal and pathological conditions.
Ligand Taxonomy for Bioinorganic Modeling of Dioxygen‐Activating Non‐Heme Iron Enzymes
Authors: Park Hyunchang , Lee Dongwhan 
Published: January 2020

AbstractNovel functions emerge from novel structures. To develop efficient catalytic systems for challenging chemical transformations, chemists often seek inspirations from enzymatic catalysis. A large number of iron complexes supported by nitrogen‐rich multidentate ligands have thus been developed to mimic oxo‐transfer reactivity of dioxygen‐activating metalloenzymes. Such efforts have significantly advanced our understanding of the reaction mechanisms by trapping key intermediates and elucidating their geometric and electronic properties. Critical to the success of this biomimetic approach is the design and synthesis of elaborate ligand systems to balance the thermodynamic stability, structural adaptability, and chemical reactivity. In this Concept article, representative design strategies for biomimetic atom‐transfer chemistry are discussed from the perspectives of “ligand builders”. Emphasis is placed on how the primary coordination sphere is constructed, and how it can be elaborated further by rational design for desired functions.
Halogen–C2H2 Binding in Ultramicroporous Metal–Organic Frameworks (MOFs) for Benchmark C2H2/CO2 Separation Selectivity
Authors: Mukherjee Soumya , He Yonghe , Franz Douglas , Wang Shi‐Qiang , Xian Wan‐Ru , Bezrukov Andrey A. , Space Brian , Xu Zhengtao , He Jun , Zaworotko Michael J. 
Published: January 2020

AbstractAcetylene (C2H2) capture is a step in a number of industrial processes, but it comes with a high‐energy footprint. Although physisorbents have the potential to reduce this energy footprint, they are handicapped by generally poor selectivity versus other relevant gases, such as CO2 and C2H4. In the case of CO2, the respective physicochemical properties are so similar that traditional physisorbents, such as zeolites, silica, and activated carbons cannot differentiate well between CO2 and C2H2. Herein, we report that a family of three isostructural, ultramicroporous (<7 Å) diamondoid metal–organic frameworks, [Cu(TMBP)X] (TMBP=3,3′,5,5′‐tetramethyl‐4,4′‐bipyrazole), TCuX (X=Cl, Br, I), offer new benchmark C2H2/CO2 separation selectivity at ambient temperature and pressure. We attribute this performance to a new type of strong binding site for C2H2. Specifically, halogen⋅⋅⋅HC interactions coupled with other noncovalent in a tight binding site is C2H2 specific versus CO2. The binding site is distinct from those found in previous benchmark sorbents, which are based on open metal sites or electrostatic interactions enabled by inorganic fluoro or oxo anions.
Circulating epigenetic biomarkers for detection of recurrent colorectal cancer
Authors: Symonds Erin L. , Pedersen Susanne K. , Murray David , Byrne Susan E. , Roy Amitesh , Karapetis Christos , Hollington Paul , Rabbitt Philippa , Jones Frederick S. , LaPointe Lawrence , Segelov Eva , Young Graeme P. 
Published: January 2020

BackgroundThe sensitive detection of recurrent colorectal cancer (CRC) by the measurement of circulating tumor DNA (ctDNA) might improve the chance of a cure. This study compared a quantitative methylated ctDNA test with carcinoembryonic antigen (CEA) in the setting of surveillance for recurrence.MethodsBlood samples collected either during surveillance or within 12 months of the confirmation of recurrence were assayed for ctDNA (methylated branched‐chain amino acid transaminase 1 [BCAT1]/Ikaros family zinc‐finger 1 protein [IKZF1]) and CEA. The optimal ctDNA threshold was determined by receiver operating characteristic analysis, and the test performance for the detection of recurrence was compared with CEA (5 ng/mL threshold).ResultsThe study cohort comprised 144 eligible patients and included 50 recurrence events. The sensitivity of the methylated ctDNA test for recurrence was 66.0% (95% confidence interval [CI], 57.1%‐69.3%), which was significantly higher than the sensitivity of CEA (31.9%; 95% CI, 22.8%‐36.6%; P < .001). The sensitivity for resectable recurrence (n = 20) was also higher (ctDNA, 60.0%; CEA, 20.0%; P = .01). The specificity did not differ between the tests (ctDNA, 97.9%; 95% CI, 93.2%‐99.6%; CEA, 96.4%; 95% CI, 91.4%‐99.0%). When adjustments were made for other predictors of the presence of recurrence, a positive ctDNA test was an independent predictor (odds ratio, 155.7; 95% CI, 17.9‐1360.6; P < .001), whereas CEA was not (odds ratio, 2.5; 95% CI, 0.3‐20.6; P = .407).ConclusionsThe quantitative ctDNA test showed superior sensitivity in comparison with CEA without a difference in the specificity for detecting recurrent CRC. Longitudinal studies are warranted to further assess the utility (specifically the survival benefit) of methylated BCAT1/IKZF1 ctDNA in the surveillance of patients with CRC.
Ownership structure, stakeholder engagement, and corporate social responsibility policies: The moderating effect of board independence
Authors: Zaid Mohammad A. A. , Abuhijleh Sara T. F. , Pucheta‐Martínez María Consuelo 
Published: January 2020

AbstractThis study primarily purposes to empirically examine the impact of stakeholder engagement mechanism in the form of professional shareholders on the corporate social responsibility (hereafter CSR) disclosure and how the previous nexus is shaped and moderated by the level of board independence within a dynamic framework. An agency theory framework is adopted to understand the extent to which professional shareholders, such as government, institutional, and foreign, influence the firm's CSR reporting. To the best of our knowledge, most of the prior studies in the CSR field have not yet provided a profound analysis of the moderating effect of board independence on the relationship between ownership structure and CSR disclosure. Hence, working on this sensitive issue merits our attention and deserves our recognition. Due to endogeneity bias, our reported results vary in their significance level across the three econometric models: pooled ordinary least square, fixed effects, and two‐step system generalized method of moments. The findings unveiled that the effect of government, institutional, and foreign investors on CSR disclosure is more positive under conditions of the high level of board independence. The study sheds new light onto the paradoxical empirical findings of the prior research that has tried to link ownership structure to CSR disclosure directly by analyzing the significant role of independent directors on the aforementioned nexus. Further, this study pays rigorous attention to provide multidimensional insights for responsible parties to support the notion of stakeholder engagement mechanism beyond the current boundaries.