bluuebunny/crossref_metadata_2025_split huggingface dataset:
El cambio climático y los impactos socioeconómicos sobre la zona costera e insular colombiana
Authors: Hernández Narváez Desireé María , Vega Cabrera Alejandra María , Zamora Bornachera Anny Paola , Sierra Correa Paula Cristina 
Published: November 2019

Climate change has a global-level impact, with effects on natural and human systems, and in particular coastal zones have been recognized as area sensitive to threats of sea level rise (SLR) and coastal erosion. This exercise was carried out in order to identify the impacts of climate change at a socioeconomic level in Colombia’s coastal zone, which is composed of 12 departments with 60 municipalitiesframed within ten Coastal Environmental Units (UAC). Methodologically, 23 indicators were defined using the risk approach, that combines the exposure (14 indicators), sensitivity (6 indicators) and adaptive capacity (3 indicators), framed within food security, human habitat, andinfrastructure dimensions. To do this, official information databases were built regarding the socioeconomic elements exposed, combined with the use of the SLR and coastal erosion-affected areas report, elaborated by Invemar within the Third National Communication on Climate Change framework. With this report data, indicator matrices were built and the levels of affectation in each indicator were calculated using distribution by quintiles. The results show that towards the year 2100, about 5% of the population and 4.3% of houses will be affected by SLR, especially in the Guapi and Mosquera (Cauca) and La Tola (Nariño) municipalities in the Pacific region and Remolino, Sitio Nuevo and Pueblo Viejo (Magdalena) municipalities in the Caribbean. In addition, tourist areas could lose 13% due to coastal erosion, and 5.9% of the port infrastructure and 12% of the roads could be flooded by SLR. These results constitute an input to support territorial planning, as well asthe formulation of municipal and sectoral plans for climate change management on Colombia’s coasts.
Caracterización de las asociaciones de cocolitóforos en las cuencas offshore del Pacífico colombiano
Authors: Osorio-Gòmez Esteban , Vallejo Hincapie Diego , Rincón-Martínez Daniel , Restrepo-Acevedo Sandra , Pardó-Trujillo Andres , Trejos-Tamayo Raúl 
Published: November 2019

This study was conducted on coccolithophores recovered from 39 piston-core samples taken offshore Chocó and Tumaco basins, on the Colombian Pacific. Qualitative and quantitative analyses of the coccoliths showed changes in the relative abundances and the state of preservation in the two basins. The examined sediments were characterized by the coccoliths Gephyrocapsa oceanica, Gephyrocapsamuellerae, Gephyrocapsa <3 μm, Emiliania huxleyi, Calcidiscus leptoporus and Helicosphaera carteri, which presented abundances higher than 2 %. We also identified a minority assemblage (<2%) constituted by Ceratolithus spp., Coccolithus pelagicus, Florisphaera profunda,Helicosphaera princei, Helicosphaera sellii, Helicosphaera wallichii and Pontosphaera spp. together with reworked specimens of Reticulofenestra spp, Sphenolithus spp. and Discoaster spp. The recovery of E. huxleyi as part of the assemblage indicates that the studied sediments are younger than the biozone NN21, covering an age range of Middle Pleistocene (Ionian). The number of coccoliths per gram (cc/g) was calculated, demonstrating an average of 5.7x106 cc/g and 1.2x107 cc/g for Chocó and Tumaco basins, respectively. In order to interpret the causes of this variance, we performed a multivariate redundancy analysis (RDA), showing that the distance to the coastline is the controlling factor of the fluctuations of the relative abundances and distribution of the coccoliths in both basins.
The effects of IGF-I on prostate cancer progression and the influence of hyperglycaemia
Authors: Rehanna Mansor  , Jeff Holly  , Claire Perks  
Published: November 2019

Epithelial to mesenchymal transition (EMT) is a necessary process in the conversion of benign tumor to aggressive and highly invasive cancer. Dysregulation of the IGF system and impaired metabolic regulation have been implicated in the progression of prostate cancer. However, the mechanisms underlying these effects require further investigation. We used normal prostate epithelial cells PNT2 and DU145 prostate cancer cells. Western immunoblotting was used to determine changes in protein abundance. Trypan blue dye exclusion assay was employed to assess cell proliferation and transwell migration assays to assess cells migration. Under normal glucose conditions, IGF-I inhibited EMT in PNT2 cells demonstrated by an upregulation in the epithelial marker E-cadherin together with loss of mesenchymal markers; vimentin and fibronectin. In contrast to PNT2 cells, IGF-I induced EMT in DU145 cells, as shown by the reduction of E-cadherin level and upregulation of vimentin and fibronectin. We observed that exposure to hyperglycaemia (25mM glucose concentration) alone induced EMT in both PNT2 and DU145 cells. The changes in EMT markers induced by hyperglycaemia (loss of epithelial marker and increase of mesenchymal markers) associated with increased cell proliferation and migration. In high glucose conditions, IGF-I was still able to inhibit EMT in PNT2 cells, whereas in DU145 cancer cells, the addition of IGF-I could not enhance EMT any further. In conclusion, IGF-I and hyperglycaemia play important roles in promoting prostate cancer cell progression through the regulation of EMT programme.
Mental Health /Depression at Workplaces
Authors: Asrenee AB. Razak  
Published: November 2019

There is an increasing trend of mental health issues in Malaysia. 1 in 3 Malaysian aged over 16 years old is at risk of having a mental health problem, and the trend is on the rise. The burden of mental health disorders on health and productivity, however, has long been underestimated. It is partly due to the cultural stigma attached to mental disorders. The recent 2018 Malaysia's Healthiest Workplace survey reported that more than half of employees in the survey have been affected by job-related stress such as burnout, anxiety, depression, and could lead to suicide. The serious consequences of these mental health issues not only affecting the individual but also lead to negative impacts on the productivity and performance of the company. On the other hand, workplaces that promote good mental health, and support people with mental disorders are more likely to reduce absenteeism, increase productivity as well as could benefit from associated economic gains. It is crucial for the workplace to integrate mental health intervention in their health and wellbeing strategy. Among the useful intervention is mindfulness training. Mindfulness is not only proven to reduce the work stress but also teaches the employees to appreciate life and positively cope with their job demands. This presentation outlines the benefits of mindfulness and how it can be applied in daily life.
Being Fit is Trending: The good and ugly side of Fitness Trend 2019
Authors: Nur Ikhwan Mohamad  
Published: November 2019

Benefits of improved physical fitness performance for daily life functions and sports performance are well documented. In general, modern and technological-based lifestyle brought together less requirements for physical movement in performing daily tasks. This resulted in an increasing percentage of obese or sedentary populations, especially in developing and developed countries. Health and fitness industry can be said booming in this condition. Exercises may be performed due to its proven benefits, but the motivation to continue performing it may also due to it being promoted as the trend of the time. Being fit is trending. This is when the commercialization of training methods begins. Fitness training methods works based on the concept of stimuli-responses-recovery-adaptation concepts. Training variables manipulation produces various types of fitness protocols and modalities. Wrongly manipulated variables practiced under the supervision of non-qualified fitness and medical professionals may resulted in a higher risk of injury and reducing the potential of achieving the desire outcome. This presentation will discuss the top 20 past and current fitness trends and how its positive effect may actually turned to be bad for an individual's physiologically and biomechanically due to several reasons, as indicated by research.
Vaccines regulation in Malaysia
Authors: Jenny Thong Chen Ni  
Published: November 2019

The National Pharmaceutical Regulatory Agency (NPRA) is the regulatory body under the Ministry of Health (MOH) that regulates medicines (including vaccines) and cosmetics in Malaysia. NPRA is the organization body that safeguards the public health by ensuring medicines that are authorized to be in the Malaysian market are of quality, efficacious, and safe. The presentation will be focusing on the key areas in regards to vaccine regulations, including the registration pathway of vaccine, the requirements of registration of a vaccine in terms of quality, efficacy, and safety, and post-licensure activity for the vaccine (vaccine lot release). In addition, the presentation would also provide some relevant information, including the brief process of vaccine manufacturing, the contents of a vaccine, and also a case study encounter during the vaccine lot release commencement.
Copolymerization of starch-acrylamide by gamma irradiation for hydrogel
Authors: Gatot Trimulyadi Rekso  , Adjat Sudradjat  
Published: November 2019

The present study aimed to synthesize and evaluate copolymerization of starch-acrylamide by gamma irradiation for hydrogel Copolymerization of gelatinized starch and acrylamide (AAm) in aqueous medium using γ-irradiation was carried out. The preparation conditions, such as irradiation dose and AAm concentration, were investigated. The copolymers were characterized by FTIR spectroscopy, thermo-gravimetric analysis (TGA), and scanning electron microscopy (SEM). The results show that by increasing of irradiation dose, the gel fraction increases till the dose of 15 kGy. Above the stating dose, the gel fraction decreases. The Equilibrium Degree of Swelling (EDS) value slightly increases with increasing irradiation dose, and after a dose of 15 kGy is decreasing. The swelling of starch- AAm hydrogels reduced as the gel content increases. The results indicated that the optimum condition for obtaining hydrogels with desirable properties is irradiated at a dose of 15 kGy. The results indicated that SEM revealed that the higher the dose, the lower the copolymer pore size. The starch-AAm copolymers have thermal stability higher than that for starch individually.
Biological synthesis of iron oxide nanoparticles and evaluation of its antibacterial and antioxidant property
Authors: Nurul Ain Shafina Mohd Hasni  , Shahnaz Majeed  
Published: November 2019

Iron oxide nanoparticles (IONPs) have become a great interest among the researcher as it has a broad range of advantageous application in the pharmaceutical industries as well as healthcare settings. The present study was focused on the synthesis of IONPs from the aqueous extract of Piper betle leaves belongs to the genus Piper of the family Piperaceae and to evaluate the antibacterial activity against various pathogens. IONPs were synthesized from Piper betle leaf extract using 3mM of iron (III) chloride (FeCl3). The characterization of IONPs was done through UV-Vis spectroscopy, TEM, FTIR, and Zeta potential analysis. Then, the synthesized IONPs were tested for antibacterial activity against five different pathogens, which are Staphylococcus aureus, Staphylococcus epidermidis, Salmonella typhi, Escherichia coli, and Vibrio Cholera. The synergistic effect of IONPs were evaluated with ceftriaxone, gentamicin and amoxicillin. Furthermore antioxidant activity was determined using DPPH assay. The maximum absorption peak of IONPs was found at 320 nm through UV-Vis spectroscopy. The synthesized IONPs were spherical in shape with size ranges from 10 - 15 nm through TEM analysis. From FTIR spectroscopy, significant peaks were observed and showed the presence of a hydroxyl group, amine, alkane, amide, and nitrile groups, respectively. Zeta potential analysis showed IONPs were stable. The synthesized IONPs showed significant antibacterial activity against all the selected pathogens. The maximum zone of inhibition was observed on Vibrio cholera increased as the concentration of the IONPS increased. The IONPs exhibited a good synergistic effect with ceftriaxone as compared to gentamicin and amoxicillin. The IONPs showed good antioxidant properties through DPPH assay at 40 µg/ml. The IONPs were successfully synthesized from Piper betle leaf extract, which demonstrated significant antibacterial activity against various bacterial pathogens and also exhibited good antioxidant activity.
Modelos probabilísticos para eventos de precipitações extremas na Cidade de Palmares-PE (Probabilistic modeling for extreme rainfall events in the city of Palmares - PE)
Authors: De Alcântara Lucas Ravellys Pyrrho , Coutinho Artur Paiva , Dos Santos Neto Severino Martins , Melo Tássia dos Anjos Tenório de , Costa Larissa Fernandes , Ribas Larissa Virgínia da Silva , Antonino Antonio Celso Dantas , Alves Edevaldo Miguel 
Published: November 2019

A estimava da probabilidade de excedência de eventos de precipitações pluviométricas máximas pode ser realizada a partir da associação entre as séries hidrológicas e modelos probabilísticos. O presente trabalho tem por objetivo avaliar a aderência da distribuição empírica de Precipitações Diárias Máximas Anuais (PDMA), as distribuições teóricas de probabilidade de Gumbel, Log-Normal de dois parâmetros, Generalizada de Valores Extremos, Fréchet, Weibull para 2 e 3 parâmetros, Gama, Pearson e Log-Pearson para 3 parâmetros. Foi utilizada uma série histórica de precipitação máxima diária anual oriunda da cidade de Palmares-PE, a partir de dados obtidos da Agência Nacional de Águas (ANA). Para avaliar a qualidade de aderência das distribuições, foram utilizados os testes de aderência de Anderson Darling (AD), Kolmogorov-Smirnov (KS) e o teste Qui-Quadrado de Pearson (χ2). Para quantificação da qualidade dos ajustes estatísticos utilizou-se do coeficiente de determinação (R2). As distribuições de Fréchet e Weibull II não apresentaram aderência a distribuição empírica de frequência. A distribuição de Gumbel foi a que apresentou maior aderência à distribuição empírica de acordo com o teste Qui-Quadrado de Pearson (χ2), enquanto que a GVE e a Pearson III aos testes AD e KS, respectivamente. A B S T R A C TTo analyze and estimate the likelihood of new extreme precipitation events, hydrological data records and probabilistic mathematical modeling can be used associated with different recurrence frequencies. The objective of this study was to adjust the PDMA of the city of Palmares-PE, based on data obtained from the National Water Agency (ANA), the Gumbel probability distributions, Log-Normal of two Parameters, Generalized Extreme Values, Fréchet, Weibull for 2 and 3 parameters, Range, Pearson and Log-Pearson for 3 parameters. In order to evaluate the statistical distributions, the Anderson Darling (AD), Kolmogorov-Smirnov (KS) and Pearson Chi-Square (χ2) tests were used, and the quantification of the quality of the statistical adjustments was done using coefficient of determination (R2). Among the probabilistic distributions analyzed, the only ones that do not fit are the distributions of FRÉCHET and Weibull II. The Gumbel distribution was the best fit for Pearson Chi-square test (χ2), and GVE and Pearson III, respectively, for the AD and KS tests.Keywords: hydrology statistics, return time, intense rain, extreme events, random variables.
A vegetação de cerrado e a sua relação com a quiropterofauna no entorno da cavidade natural subterrânea “Toca do Inferno”, no leste do estado do Maranhão, Brasil (Cerrado vegetation and its relation to the chiropterofauna in the surroundings of the underground natural cavity "Toca do Inferno", in the east of Maranhão state, Brazil)
Authors: Pinheiro Claudio Urbano Bittencourt , Fernandes Bianca dos Santos 
Published: November 2019

A caverna “Toca do Inferno”, localizada no município de Barão de Grajaú, na região leste do estado do Maranhão, representa a maior cavidade natural subterrânea identificada no estado, sendo um importante abrigo para morcegos e demais animais nesta área de cerrado da região. Este estudo objetivou caracterizar e avaliar a vegetação de entorno e sua importância para a sustentabilidade do ecossistema regional. No levantamento fitossociológico foram amostrados 802 indivíduos pertencentes a 66 espécies vegetais formadas basicamente por cerrado arbóreo. Em relação a quiropterofauna, foram identificadas 16 espécies que contribuem consideravelmente com o aporte de nutrientes para a caverna, favorecendo a polinização e disseminação de sementes, que ajuda na manutenção e na regeneração da vegetação. A consulta aos moradores revelou a percepção local em relação à caverna e ao ambiente em geral. A maioria não concebe a caverna como um elemento importante para a região. Ficou evidente a necessidade de atividades relacionadas à educação ambiental para demonstrar a relevância e interação destes elementos. A B S T R A C TThe cave “Toca do Inferno”, located in the municipality of Barão de Grajaú, east region of state of Maranhão, represents the major natural underground cavity in the state, important shelter for bats and others animals in this region of cerrado vegetation. This study aimed to characterize and to evaluate the surroundin vegetation and its importance to the ecosystem sustainability. A socioenvironmental analysis was developed in communities surrounding the cave. In the phytosociological inventory, 802 individuals, belonging to 66 plant species of arboreous cerrado were sampled. About the bat fauna, 16 species were identified. Besides to aid in pollination and seed dispersion, the bats help in the maintenance and restoration of the cerrado vegetation. The interviews with local dwellers were essential to analyze the perception about the environment and the cave. A greater number of local people does not perceive the cave as an important element to the region. It is clear the necessity of activities related to environmental education to demonstrate the relevance and interaction between these elements.Keywords: Vegetation, Cerrado, Caves, Conservation.
IDENTIFICAÇÃO DE EXTREMOS DE CHUVA NA MESORREGIÃO METROPOLITANA DE BELÉM: O USO DO MODELO BOX PLOT PARA A GESTÃO SOCIOAMBIENTAL (Identification of rain extremes in the metropolitan mesorregion of Belém: the use of the model box plot for the socio-environmental management)
Authors: Da Silva Santos Marcos Ronielly , Vitorino Maria Isabel , Sodré Giordani Rafael Conceição , Oliveira Verônica Gabriella 
Published: November 2019

Este artigo apresenta a acurácia do modelo estatístico “Box plot” para a identificação de eventos extremos positivos e negativos de chuva, com vista, ao gerenciamento da gestão socioambiental municipal. Para tanto, utilizou-se dados mensais de precipitação, proveniente da técnica de sensoriamento remoto para a mesorregião metropolitana de Belém, durante o período de janeiro de 2000 a dezembro de 2010. Observando a carência de metodologias específicas para a climatologia de eventos extremos e áreas correlatas a gestão ambiental, propõem-se a utilização de métodos oportunos, que visem contribuir para a análise e compressão da variabilidade de extremos climáticos e seus efeitos para a gestão socioambiental. A utilização de anos excepcionais é importante por contribuir com o entendimento das possíveis variabilidades que ocorrem na circulação atmosférica e que refletem nos meses dos anos secos e chuvosos. Portanto, o conhecimento prévio dos eventos de extremos de chuva deve auxiliar a gestão ambiental dos municípios, visando o melhor ordenamento territorial e diminuindo a vulnerabilidade da sociedade frente às intempéries do tempo. A B S T R A C TThis article presents the accuracy of the Box plot statistical model for the identification of extreme positive and negative rainfall events with a view to the management of municipal social and environmental management. For that, monthly precipitation data from the remote sensing technique for the metropolitan mesoregion of Belém were used during the period from January 2000 to December 2010. Observing the lack of methodologies specific to the climatology of extreme events and areas related to environmental management, it is proposed to use timely methods that contribute to the analysis and compression of the variability of climatic extremes and their effects for environmental management. The use of exceptional years is important because it contributes to the understanding of the possible variabilities that occur in the atmospheric circulation and that reflect in the months of the dry and rainy years. Therefore, previous knowledge of extreme events should help the environmental management of municipalities, aiming at better territorial planning and reducing the vulnerability of society against the weather.Keywords: rain, socio-environmental, statistics.
CONDICIONANTES PARA ELABORAÇÃO DE UM MODELO CONCEITUAL HIDROGEOLÓGICO DA SUB-BACIA DO RIBEIRÃO RODEADOR, BACIA DO RIO DESCOBERTO/DF, COMO FERRAMENTA PARA A GESTÃO INTEGRADA DE RECURSOS HÍDRICOS (Conditioning factors for the elaboration of a hydrogeological conceptual model of the Ribeirão Rodeador subwatershed, Descoberto watershed river, Distrito Federal, as a tool for the integrated water resources management)
Authors: Silva Elisa Marie Sette , Cangiano Marina Rique , Da Cunha Luciano Soares , Guiguer Nilson 
Published: November 2019

O Distrito Federal tem importante papel para a hidrografia brasileira por possuir nascentes de três grandes bacias: Tocantins, Paraná e São Francisco. No entanto, na região há pouca disponibilidade hídrica frente à crescente demanda populacional. Reflexo disso, foi a crise hídrica decretada em 2017 na capital federal. A Bacia do Rio Descoberto, por ser o maior manancial do Distrito Federal (DF), possui relevante papel nesse contexto, assim como sua sub-bacia do Ribeirão Rodeador, um de seus principais afluentes. Portanto, no sentido de compreender o funcionamento hidrogeológico da sub-bacia de maneira integrada (sistemas hídricos superficiais e subterrâneos) e, assim, contribuir com o aprimoramento da gestão hídrica na bacia. Este estudo apresenta proposta de modelo conceitual hidrogeológico, elaborado a partir de classificação de imagem de satélite, análise de séries históricas de dados pluviométricos e fluviométricos e do cruzamento de dados hidrológicos com outros dados físicos integrados em um sistema de Sistema de Informações Geográficas (SIG) da bacia. Palavras-chave: Hidrologia, SIG, modelagem conceitual hidrogeológico, gestão hídrica, outorga de uso da água, Mike She. A B S T R A C TDistrito Federal has an important role for the Brazilian hydrography because it has springs of three large basins: Tocantins, Paraná and São Francisco. However, there is little water availability in the region facing the growing population demand. Consequently, in 2017 a water crisis was declared in the federal capital. The Descoberto River Basin, for being the largest source in the Federal District, has a relevant role in this context, as well as its sub-basin of Ribeirão Rodeador, one of its main tributaries. Therefore, in order to understand the hydrogeological functioning of the sub-basin in an integrated manner (surface and underground water systems) and thus to contribute to the improvement of water management in the basin, this study presents a hydrogeological conceptual model, elaborated from classification of satellite image, analysis of historical series of pluviometric and fluviometric data, and crossing of hydrological data with basin GIS.Keywords: Hydrology, SIG. hydrogeological conceptual modeling, water management, water use license, Mike She.