bluuebunny/crossref_metadata_2025_split huggingface dataset:
Algorithm for assessing the completeness of seed treatment of wheat and barley
Authors: Chervyakova L. , Panchenko T. , Tsurkan O. , Adamenko N. 
Published: August 2020

Goal. To develop a method for the determination of imidacloprid, clothianidin, prothioconazole and tebuconazole in the treatment seeds of wheat and barley.
Methods. Active substances were determined by thin layer chromatography (TLC). Mathematical-statistical method for evaluate the linear range of the dependence of the area of the chromatographic zone on the amount of active substance was used.
Results. The determination of pesticides includes a number of basic stage: characteristic the matrix by the ratio of the content of coextracting substances, that interfere with the determination, and the content of pesticides; classification of pesticides by polarity in according to the dipole moment (µ, D); extraction from the analyzed sample by organic solvent with corresponding of the dielectric constant, ε; purification; qualitative and quantitative determination. In the case of the analysis of treatment seeds, in which the amount of pesticides is much greater than coextracting compounds, the stages of classification and purification are excluded from the analysis. The extraction is carried out with ethanol. Qualitative determination of pesticides is carried out on plates with a thin layer of adsorbent (silicagel) in the mobile phase (mixture of hexane and ethanol, ε = 7.49) with using corresponding reagents. Silver ammonia (AgNO3) solution and followed by UV irradiation of the chromatogram is used for identification halogen-containing pesticides (zones of localization of compounds are formed dark spots of reduced silver). Pesticides containing donor atoms of sulfur, nitrogen, oxygen, identify by bromphenol blue (BPB) and subsequent bleaching of the background with an solution of citric acid (zones of localization of compounds are formed blue spots form on a light background). The active substances are identified with the corresponding Rf of the zones localization. Quantitatively of active substances is determined by the calibration dependence of the area of compound’ chromatographic zone on its quantity. For all four compounds, this dependence is linear in the concentration range of 0.20 — 0.80 µg and is described by the regression equation for: imidacloprid y = 6.25x + 5.45; for clothianidine y = 11.65x + 6.70; for prothioconazole y = 28.7x + 2.05; for tebuconazole y = 13.00x + 7.00. In all cases, the correlation between the indicators is estimated as strong (r = 0.99).
Conclusions The algorithm for assessing the completeness of the treatment of wheat and barley seeds is an express control method and using the thin layer chromatography method allows to determine four active substances in one sample during one analysis with high accuracy (relative error of less than 5% at n = 5, P = 0.95) excluding laborious experiment.
Evaluation of efficacy of modern fungicides against fusarium head blight on winter wheat
Authors: Dzham M. 
Published: August 2020

Goal. To study the influence of modern biological and chemical preparations on the development of fungi of the genus Fusariumunder conditions of artificial inoculation.
Methods. The efficacy of fungicides was studied in 2018—2019 in the Zhytomyr region, Pulinsky district under the conditions of artificial inoculation on winter wheat of the Bogdan variety. Mixture of conidia of the fusarium fungi (F. graminearum, F. culmorum, F. poae, F. avenaceum) was used for ear inoculation. The plot area was 2 m2 in four replications, the plot placement was randomized. The inoculation of winter wheat ears was carried out at the phase of mass flowering. At the phase of milky-wax maturity, records were taken to determine the spread and development of the disease. The following fungicides were used to protect wheat crops: Folicur BT EC, 1.2 l/ha, Magnello 350 EC, 1.0 l/ ha, Haupsin, 0.2 l/ha, Fitodoktor, 0.05 kg/ha, Alliot 250 EC, 0.5 l/ ha, Bumper Super EC, 1.2 l/ha and mixtures of Magnello 350 EC, 0.75 l/ha + Haupsin 0.2 l/ha, Magnello350 EC, 0.75 l/ha + Fitodoktor, 0.05 kg/ha.
Results. The results obtained during the years of investigationsindicate that the used preparations are efficient for the protection of crops from fusarium head blight on winter wheat. However,not all fungicides tested had high enough efficacy. The most effective against the pathogens F.graminearum, F. culmorum, F. poae, F. avenaceumunder conditions of Zhytomyr region were fungicides Folicur BT EC, 1.2 l/ha, Magnello 350 EC, 1.0 l/ha and mixtures of fungicide and biological preparation (Magnello 350 EC, 0.75 l/ ha + Haupsin, 0.2 l/ha). Efficacy of fungicides used against these pathogens ranged from 69.2% to 75.2%. After fungicide application the weight of 1000 grains increased by 7.3—13.6 g. Significant difference between experimental variants and untreated check on 1000 grain weight was noted. With the use of fungicides, the yield increased by 22.3—24.8%.
Conclusions. The analysis of the protection against fusarium head blight convinces the need to apply chemical protection measures when weather conditions are favorable for the development of the disease. In the growing seasons of 2018—2019, under conditions of the Zhytomyr region, the most promising and effective against the pathogens F.graminearum, F. culmorum, F. poae, F. avenaceum were fungicides Folicur BT EC, 1.2 l/ha, Magnello 350 EC, 1.0 l/ ha and mixtures of fungicide and biological preparation Magnello 350 EC, 0.75 l/ ha + Haupsin, 0.2 l/ha.
Polymorphism of Ukrainian common winter wheat cultivars with respect to the molecular marker for the gene conferring moderate resistance against Fusarium head blight
Authors: Kozub N. , Sozinova O. , Karelov A. , Sozinov I. , Kucheriavyi I. , Tishchenko V. , Batashova M. , Gusenkova O. , Blume Ya. 
Published: August 2020

Goal. The goal of the work was to evaluate the genetic potential of resistance to Fusarium head blight of collections of winter common wheat cultivars based on the allelic state of the TDF_076_2D gene conferring moderate resistance against Fusarium graminearum Schwabe and F. culmorum (W.G.Sm.) Sacc. fungi.
Materials and methods. We studied 68 winter common wheat cultivars developed in different scientific-breeding institutions of Ukraine (the Myronivka Remeslo Institute of Wheat of NAAS, the Plant Breeding and Genetics Institute (PBGI), the Рlant Production Institute nd. a. V. Ya. Yuryev of NAAS, Poltava State Agrarian Academy (PSAA)). A silica-based commercial kit was used for DNA extraction. To detect the allelic state of the resistance gene, the INDEL1 marker cosegregating with the TDF_076_2D gene was used. Amplified fragments obtained as a result of PCR were separated in 3% agarose gel and visualized with use of ethidium bromide.
Results. The frequency of the resistance allele according to the INDEL1 marker for the gene conferring moderate resistance to the Fusarium fungi ranged from 0.682 in the sample of PBGI cultivars to 0.882 in the PSAA group; the frequency of the resistance allele in the total sample made up 0.782. It was found that the cultivar ‘Poliovyk’ showed a non-typical pattern of amplified bands, which possibly indicates the allele for susceptibility to Fusarium head blight.
Conclusions. The majority of the common wheat cultivars from the studied sample carry the resistance allele of the marker for the gene of interest. The data obtained are consistent with the results of the previous research of the wider sample of the winter and spring common wheat cultivars. The cultivars with the resistance allele might show a lower infection level in the field and serve as a source of the gene in marker assisted selection. The cultivar ‘Poliovyk’ is worth more detailed studying with use of other molecular markers for the TDF_076_2D gene and (or) sequencing to find out a precise allelic state of the gene.
Odontometrí­a y variantes morfológicas dentales en piezas dentarias del maya prehispánico del Museo Nacional de Arqueologí­a y Etnologí­a de Guatemala (MUNAE)
Authors: Fernández Rodas Francisco René , Rosales Escribá Guillermo , Zuleta Mejí­a Sergio José 
Published: August 2020

uatemala es conocida mundialmente por sus volcanes, lagos, flora y fauna, por sus colores, su cultura, sus tradiciones y por su gente amable y trabajadora; además de todo eso Guatemala tiene la dicha de ser llamada ”La Cuna de la Civilización Maya”. Por todo lo descrito anteriormente, nace la inquietud de realizar un estudio que reúna por primera vez datos sobre variantes morfológicas y odontométricas de los dientes de la población maya del perí­odo prehispánico. En la presente investigación fueron estudiadas, analizadas y medidas todas las piezas dentales permanentes evaluables (apico-coronalmente), así­ como las variantes morfológicas tales como: diente en pala, enanismo radicular, tubérculo de carabelli, tubérculo sextum, etc., que se encontraron en la población maya estudiada. Para la elaboración de esta investigación se contó con el apoyo profesional del Dr. Guillermo Rosales Escribá, quien con su experiencia en el campo de la Morfologí­a y Anatomí­a Dental aportó su conocimiento para poder completar este estudio, así­ como la colaboración de las autoridades y personal del ”Museo Nacional de Arqueologí­a y Etnologí­a de Guatemala (MUNAE)”, quienes prestaron las piezas dentales que se utilizaron para esta investigación. El MUNAE es una institución pública guatemalteca encargada de la conservación, investigación y difusión de los bienes arqueológicos y etnológicos, pertenecientes al Patrimonio
Cultural de la Nación de Guatemala
The Risk of Cardiovascular Events Associated With Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis
Authors: Ozen Gulsen , Pedro Sofia , Michaud Kaleb 
Published: August 2020

ObjectiveTo examine the comparative effects of biologic disease-modifying antirheumatic drugs (bDMARD) and tofacitinib against conventional synthetic DMARD (csDMARD) on incident cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA).MethodsRA patients with ≥ 1 year of participation in the FORWARD study, from 1998 through 2017, were assessed for incident composite CVD events (myocardial infarction, stroke, heart failure, and CVD-related death validated from hospital/death records). DMARD were categorized into 7 mutually exclusive groups: (1) csDMARD-referent; (2) tumor necrosis factor-α inhibitor (TNFi); (3) abatacept (ABA); (4) rituximab; (5) tocilizumab; (6) anakinra; and (7) tofacitinib. Glucocorticoids (GC) were assessed using a weighted cumulative exposure model, which combines information about duration, intensity, and timing of exposure into a summary measure by using the weighted sum of past oral doses (prednisolone equivalent). Cox proportional hazard models were used to adjust for confounders.ResultsDuring median (IQR) 4.0 (1.7–8.0) years of follow-up, 1801 CVD events were identified in 18,754 RA patients. The adjusted model showed CVD risk reduction with TNFi (HR 0.81, 95% CI 0.71–0.93) and ABA (HR 0.50, 95% CI 0.30–0.83) compared to csDMARD. While higher GC exposure as weighted cumulative exposure was associated with increased CVD risk (HR 1.15, 95% CI 1.11–1.19), methotrexate (MTX) use was associated with CVD risk reduction [use vs nonuse HR 0.82, 95% CI 0.74–0.90, and high dose (> 15 mg/week) vs low dose (≤ 15 mg/week) HR 0.83, 95% CI 0.70–0.99].ConclusionABA and TNFi were associated with decreased risk of CVD compared to csDMARD. Minimizing GC use and optimizing MTX dose may improve cardiovascular outcomes in patients with RA.
Evaluation of Bone Erosions in Rheumatoid Arthritis: The Ultrasound Score for Erosions Versus the Modified Sharp/van der Heijde Score for Erosions
Authors: Grosse Julien , Allado Edem , Albuisson Éliane , Pierreisnard Audrey , Couderc Marion , Chary-Valckenaere Isabelle , Loeuille Damien 
Published: August 2020

Objective.To evaluate the relationship between the UltraSound Score for Erosions (USSe) and the modified Sharp/van der Heijde score for erosions (SHSe).Methods.One hundred eight patients with rheumatoid arthritis (RA) were included. On radiography, SHSe was evaluated by 2 or 3 blinded readers (in case of discordance). On ultrasonography, erosions were scored on 6 bilateral joints (metacarpophalangeal joints 2,3,5; metatarsophalangeal joints 2,3,5) with a 4-point scale to calculate the USSe.Results.The Pearson correlation was good (r = 0.68, P < 0.001) and the agreement illustrated by a Bland-Altman plot was excellent (91%) between the 2 scores, which were complementary in detecting erosions.Conclusion.The USSe seems to be a valuable tool for assessing erosive damage in RA.
IgA Vasculitis With Underlying Liver Cirrhosis: A French Nationwide Case Series of 20 Patients
Authors: Elhani Ines , Pillebout Evangéline , Terrier Benjamin , Hankard Antoine , Vrtovsnik François , Jourde-Chiche Noémie , Greillier Sophie , Groh Matthieu , Belfeki Nabil , Bigot Adrien , de Boysson Hubert , Pageaux Georges-Philippe , Raffray Loïc , Urbanski Geoffrey , Ollivier Isabelle , Maillot Francois , Aouba Achille , Audemard-Verger Alexandra ,   Alexandra Audemard-Verger on behalf of the French Vasculitis Study Group (FVSG) and the HSPrognosis Group
Published: August 2020

ObjectiveImmunoglobulin A vasculitis (IgAV) and nephropathy (IgAN) share common immunological mechanisms. Liver cirrhosis is well known to be associated with IgAN. Here, we aimed to describe the presentation and outcome of IgAV patients with underlying cirrhosis.MethodsWe conducted a French nationwide retrospective study of adult patients presenting with both IgAV and cirrhosis. Baseline characteristics were compared to those of the 260 patients included in the French nationwide IgAV registry (IGAVAS).ResultsTwenty patients were included, and 7 (35%) were female. The mean ± SD age was 62.7 ± 11 years. At baseline, compared with IGAVAS patients, patients with underlying cirrhosis were older (62.7 ± 11 vs 50.1 ± 18, P < 0.01) and displayed more constitutional symptoms (weight loss 25% vs 8%, P = 0.03). Patients with underlying cirrhosis were also more likely to exhibit elevated serum IgA levels (5.6 g/L vs 3.6 g/L, P = 0.02). Cirrhosis and IgAV were diagnosed simultaneously in 12 patients (60%). Cirrhosis was mainly related to alcohol intake (n = 15, 75%), followed by nonalcoholic steato-hepatitis (n = 2), chronic viral hepatitis (n = 1), hemochromatosis (n = 1), and autoimmune hepatitis (n = 1). During follow-up with a median of 17 months (IQR 12–84), 10/13 (77%) exhibited IgAV remission at Month 3. One patient presented a minor relapse. Six patients died, but no deaths were related to IgAV.ConclusionWe report the first case series of IgAV patients with underlining cirrhosis, to our knowledge, which was mainly alcohol related. The liver disease did not seem to affect baseline vasculitis characteristics. Physicians should investigate the existence of liver cirrhosis at IgAV diagnosis, especially in the context of alcohol abuse.
Epidermal Neurite Density in Skin Biopsies From Patients With Juvenile Fibromyalgia
Authors: Boneparth Alexis , Chen Shan , Horton Daniel B. , Moorthy L. Nandini , Farquhar Ian , Downs Heather M. , Lee Hang , Oaklander Anne Louise 
Published: August 2020

ObjectiveFibromyalgia (FM) is defined by idiopathic, chronic, widespread musculoskeletal pain. In adults with FM, a metaanalysis of lower-leg skin biopsy demonstrated 45% pooled prevalence of abnormally low epidermal neurite density (END). END < 5th centile of the normal distribution is the consensus diagnostic threshold for small-fiber neuropathy. However, the clinical significance of END findings in FM is unknown. Here, we examine the prevalence of small-fiber pathology in juvenile FM, which has not been studied previously.MethodsWe screened 21 patients aged 13–20 years with FM diagnosed by pediatric rheumatologists. Fifteen meeting the American College of Rheumatology criteria (modified for juvenile FM) underwent lower-leg measurements of END and completed validated questionnaires assessing pain, functional disability, and dysautonomia symptoms. The primary outcome was proportion of FM patients with END < 5th centile of age/sex/race-based laboratory norms. Cases were systematically matched by ethnicity, race, sex, and age to a group of previously biopsied healthy adolescents with selection blinded to biopsy results. All 23 controls matching demographic criteria were included.ResultsAmong biopsied juvenile FM patients, 53% (8/15) had END < 5th centile vs 4% (1/23) of healthy controls (P < 0.001). Mean patient END was 273/mm2 skin surface (95% CI 198–389) vs 413/mm2 (95% CI 359–467, P < 0.001). As expected, patients with FM reported more functional disability, dysautonomia, and pain than healthy controls.ConclusionAbnormal END reduction is common in adolescents with FM, with similar prevalence in adults with FM. More studies are needed to fully characterize the significance of low END in FM and to elucidate the clinical implications of these findings.
Quel(s) format(s) pédagogique(s) pour la lecture analytique en classe de Seconde ?
Authors: Berneron Christelle 
Published: August 2020

Les démarches pour aborder l’étude des textes littéraires au lycée ont connu des mutations ces vingt dernières années impliquant une reconfiguration du format pédagogique du cours. En effet, le cours magistral dialogué, longtemps employé pour mener une explication de texte ne convient plus aux prescriptions induites par la lecture analytique. A-t-il disparu pour autant ? Des éléments de réponse émergent de l’analyse des autocaptations vidéo de séances de lectures analytiques en classe de Seconde réalisées en 2015-2016 par une enseignante engagée dans la recherche sur les Pratiques effectives de la lecture analytique dans le secondaire (PELAS). Cette analyse, qui prend appui sur les définitions des formats pédagogiques, sur les conclusions des recherches menées sur le cours magistral et ses dialogismes et sur l’histoire de l’étude des textes littéraires, démontre la persistance du format pédagogique du cours magistral dialogué dans les pratiques effectives de la lecture analytique observées.
Lectures analytiques et étude d’une œuvre intégrale : articulations et enjeux
Authors: Eugène Maïté , Gennaï Aldo 
Published: August 2020

L’article examine, dans une perspective descriptive et compréhensive, la manière dont les lectures analytiques menées dans le cadre de l’étude d’une œuvre intégrale s’articulent avec les autres modalités d’étude de l’œuvre, articulation, dont le nouveau programme de français de première des voies générales et technologiques, signale la nécessité : « l’interprétation d’une œuvre suppose en effet un travail d’analyse interne alternant l’explication de certains passages et des vues plus synthétiques et transversales ». Comment, dans deux classes de lycée (Seconde et Première scientifique), la lecture analytique des extraits s’agence-t-elle avec l’étude de l’œuvre intégrale et de son « économie » générale ? La lecture analytique y constitue-t-elle un outil puissant pour dire quelque chose du tout à partir d’extraits ? Il apparait que, tout en permettant la construction de savoirs sur l’œuvre intégrale, les lectures analytiques dispensent des connaissances qui transcendent l’extrait et l’œuvre.
« Hélas ! » d’Antiochus : l’émergence d’une relation esthétique
Authors: Augé Claire 
Published: August 2020

Dans le cadre de la formation d’un lecteur autonome et expert, de jeunes lecteurs sont amenés à émettre un avis personnel esthétique sur le « Hélas » d’Antiochus qui clôt la tragédie racinienne de Bérénice , objet d’une dispute littéraire séculaire. La recherche, s’appuyant sur les travaux de C. Gabathuler et de V. Larrivé, part d’une double hypothèse : les interactions entre pairs, associées à un lâcher prise de l’enseignant, permettent de faire naitre une relation esthétique personnelle au texte littéraire ; la lecture empathique aide à faire émerger une lecture experte au sein de ces interactions. Elle rend ainsi compte d’une expérimentation menée dans une classe de première. Dans un premier temps, une lecture empathique et parcellaire est proposée : chaque élève est associé à l’un des trois personnages principaux et ne lit que les scènes où son personnage apparait. Dans un deuxième temps, réunis en « cercles de personnage », les élèves écrivent collaborativement un « journal de personnage ». La lecture de l’œuvre devient coopérative au cours d’échanges menés avec tous les élèves de la classe permettant de faire naitre une relation esthétique.
En passant par l’approche analytique de la peinture…
Authors: Claude Marie-Sylvie 
Published: August 2020

Les programmes de français du secondaire, en France, prescrivent l’étude d’œuvres picturales en lien avec les œuvres littéraires. Cette étude, nommée lecture de l’image , est présentée comme un contenu disciplinaire complémentaire de celle des textes littéraires, voire comme une propédeutique. L’article cherche à interroger l’approche analytique des textes en faisant un détour par cette autre approche analytique que, d’après nos recherches, les élèves réussissent mieux. La comparaison avec la peinture est prise comme un révélateur pour comprendre certaines difficultés didactiques posées par l’analyse des textes, et pour faire apparaitre des pistes pour y remédier. L’étude s’appuie sur une enquête consacrée aux attendus des enseignants et aux pratiques des élèves sur les deux arts. Les références théoriques croisent la didactique de la littérature, les sciences des arts et, en sociologie des apprentissages, la compréhension de ces apprentissages scolaires comme configurant trois registres : cognitif, culturel et identitaire symbolique.
Le confinement à Mayotte : récit d’expérience dans un espace français singulier
Authors: Cottereau Victoire 
Published: August 2020

Cet article est un récit d’expérience personnelle du confinement au sein du département français de Mayotte. Je montre comment les mesures sanitaires ont amené mon quotidien et mon « espace vécu » à se métamorphoser dans ce territoire singulier.
Un kilomètre du jardin à la canopée. Espace vécu et expérience spatiale
Authors: Joublot Ferré Sylvie 
Published: August 2020

Cet article présente la manière dont l’espace vécu s’est trouvé affecté par des événements circonstanciels et exceptionnels tels que le confinement et les conditions restreintes de sorties, imposés en France entre le 17 mars et 11 mai 2020. Une expérience spatiale ordinaire est mise à l’étude : une marche à pied récurrente dans l’espace proche en moyenne montagne. Il s’agit plus précisément de mettre l’accent sur l’expérience spatiale comme un concept opératoire et réflexif dans le cadre de la spatialité individuelle. C’est l’occasion de questionner d’un point de vue épistémologique, heuristique et conceptuel les questions de l’espace vécu et de l’habiter.
Paysage sensible art-science d’un confinement sur le littoral breton : mise en relief d’un calligramme géopoétique
Authors: Lamontagne Nancy , Collin Antoine 
Published: August 2020

La pandémie de la covid-19 provoqua, en France, des mesures gouvernementales exceptionnelles, à savoir un état d’urgence sanitaire sous la forme d’un confinement strict le mardi 17 mars 2020. Bien qu’uniformément appliquée au territoire, la règle de sortie du domicile à moins d’un kilomère en moins d’une heure se déclina en fonction de la géographie. Sur le littoral breton de la Côte d’Emeraude, le confinement constitua un laboratoire pour la mise en place d’un système art-science, producteur d’une œuvre transdisciplinaire : une mise en relief d’un paysage littéraire. Le trajet bi-circadien d’entretien physique a ainsi délimité et défini une géomorphologie sensible d’une île-paysage, à travers la co-création d’isoplètes d’imagination, dénommées « isoeides ».
Un confinement handicapé : espace social et espace corporel face au Covid-19
Authors: Laurent Michael J.P. 
Published: August 2020

Le confinement mondial lié au Covid-19 amène a nous intérroger sur les notions de vulnérabilité et d'interdépendance, et donc sur la place des handicapés dans l'espace social. Quel enseignement tirer de cette experience mondiale de mobilité réduite ?