bluuebunny/crossref_metadata_2025_split huggingface dataset:
Measuring the effectiveness of digital nursing technologies: development of a comprehensive digital nursing technology outcome framework based on a scoping review
Authors: Krick Tobias , Huter Kai , Seibert Kathrin , Domhoff Dominik , Wolf-Ostermann Karin 
Published: March 2020

Abstract
Background
Digital nursing technologies (DNT) comprise an expanding, highly diverse field of research, explored using a wide variety of methods and tools. Study results are therefore difficult to compare, which raises the question how effectiveness of DNT can be adequately measured. Methods currently used might not be sufficient for certain specific nursing contexts. A comprehensive outcome framework that shows the multitude of possible outcome areas could be useful to generate more comparable results. The aim of the present study is to develop an outcome framework for DNT and to indicate which outcome areas have been most frequently evaluated in previous studies and how this has been done.

Methods
We combined an inductive and deductive approach to develop the framework. The numerical analysis is based on a scoping review focussing on the effectiveness of DNT for persons in need of care, formal or informal caregivers or care institutions. Nine databases were included in the screening: Medline, Scopus, CINAHL, Cochrane Library, ACM Digital Library, IEEE Xplore, the Collection of Computer Science Bibliographies, GeroLit and CareLit. Additional literature searches and expert interviews were included.

Results
The developed framework comprises four outcome target groups and 47 outcome areas. There are considerable differences in the researched outcome areas for the individual outcome target groups. Persons in need of care were by far the most frequently surveyed, particularly with respect to their psychological health. There are much fewer studies on formal and informal caregivers, and it is particularly noticeable that the quality of life of both groups has rarely been investigated. Care process quality was most frequently researched for organisations.

Conclusion
We were able to provide a comprehensive DNT outcome framework, thereby identifying the outcome tools used and the less researched outcome areas. We recommend a detailed investigation of all areas and tools in future research projects with a view to initiating a discussion on the differing importance of existing outcome areas and on a standardisation of outcome tools. We also recommend the development of outcome areas for the macro level of effectiveness assessment.
Evaluating the quality and coverage of post-abortion care in Zimbabwe: a cross-sectional study with a census of health facilities
Authors: Riley Taylor , Madziyire Mugove G. , Owolabi Onikepe , Sully Elizabeth A. , Chipato Tsungai 
Published: March 2020

Abstract
Background
An estimated 65,000 abortions occurred in Zimbabwe in 2016, and 40 % resulted in complications that required treatment. Quality post-abortion care (PAC) services are essential to treat abortion complications and prevent future unintended pregnancies, and there have been recent national efforts to improve PAC provision. This study evaluates two components of quality of care: structural quality, using PAC signal functions, a monitoring framework of key life-saving interventions that treat abortion complications; and process quality, which examines the standards of care provided to PAC patients.

Methods
We utilized a 2016 national census of health facilities in Zimbabwe with PAC capacity (n = 227) and a prospective, facility-based 28-day survey of women seeking PAC in a nationally representative sample of those facilities (n = 1002 PAC patients at 127 facilities). PAC signal functions, which are the critical services in the management of abortion complications, were used to classify facilities as having the capability to provide basic or comprehensive care. All facilities were expected to provide basic care, and referral-level facilities were designed to provide comprehensive care. We also assessed population coverage of PAC services based on the WHO recommendation for obstetric services of 5 facilities per 500,000 residents.

Results
We found critical gaps in the availability of PAC services; only 21% of facilities had basic PAC capability and 10% of referral facilities had comprehensive capability. For process quality, only one-fourth (25%) of PAC patients were treated with the appropriate medical procedure. The health system had only 41% of the basic PAC facilities recommended for the needs of Zimbabwe’s population, and 55% of the recommended comprehensive PAC facilities.

Conclusion
This is the first national assessment of the Zimbabwean health system’s coverage and quality of PAC services. These findings highlight the large gaps in the availability and distribution of facilities with basic and comprehensive PAC capability. These structural gaps are a contributing barrier to the provision of evidence-based care. This study shows the need for increased focus and investment in expanding the provision of and improving the quality of these essential, life-saving PAC services.
Omarigliptin decreases inflammation and insulin resistance in a pleiotropic manner in patients with type 2 diabetes
Authors: Hattori Sachiko 
Published: March 2020

Abstract
Background
Omarigliptin is a potent, selective, oral dipeptidyl peptidase 4 (DPP4) inhibitor with a half-life that allows weekly dosing. Inflammation or insulin resistance might be pathological mediators of cardiovascular events in patients with type 2 diabetes.

Methods
Whether omarigliptin has anti-inflammatory effects that result in decreased levels of high-sensitivity C-reactive protein (hsCRP) and anti-insulin resistance effects that decrease levels of homeostatic model assessment of insulin resistance (HOMA-IR) were investigated. Patients were allocated to continue with daily DPP4 inhibitors (control, n = 28) or to switch from daily DPP4 inhibitors to weekly omarigliptin (omarigliptin, n = 56). Fasting blood and urine samples were collected before, and every 3 months after intervention for 1 year.

Results
Omarigliptin tended to elicit reductions in fasting blood glucose (FBG), LDL-cholesterol, triglyceride, aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (γ-GTP), the urinary albumin-to-creatinine ratio (ACR) with logarithmic transformation (log ACR), and systolic and diastolic blood pressure, but the differences did not reach statistical significance compared with control. Values for HDL-cholesterol tended to increase, but also did not reach statistical significance compared with control. Omarigliptin significantly decreased HOMA-IR, remnant-like particle cholesterol (RLP-C), and hsCRP with logarithmic transformation (log hsCRP) compared with control. However, omarigliptin did not affect hemoglobin A1c (HbA1c), body mass index (BMI), and estimated glomerular filtration rates (eGFR).

Conclusion
Omarigliptin decreased inflammation and insulin resistance without affecting HbA1c or BMI. Although how DPP4 inhibitors affect cardiovascular (CV) outcomes remains uncertain, omarigliptin might confer CV benefits at least in part, via pleiotropic anti-inflammatory or anti-insulin resistance effects.
Trial registration UMIN Clinical Registry (UMIN000029288). Registered 22 September, 2017, https://upload.umin.ac.jp/UMIN000029288
Effect of episomally encoded DNA polymerases on chemically induced mutagenesis at the hisG46 target in Ames test
Authors: Grúz Petr , Shimizu Masatomi , Sugiyama Kei-ichi , Yamada Masami , Honma Masamitsu 
Published: March 2020

Abstract
Background
The standard Ames test strains owe their high sensitivity to chemical and physical mutagens to the episomal Y-family DNA polymerase RI encoded by the mucAB operon. The S. typhimurium test strains carry also another related samAB operon on a 60-kDa cryptic plasmid. In contrast to the chromosomally encoded Y-family DNA polymerases V and IV, these plasmid born polymerase genes have no direct counterpart in mammalian cells. By replicating damaged templates, DNA polymerases play a central role in mutagenesis and genome stability. It is therefore imperative to investigate their specificity to understand differences in mutagenesis between the prokaryotic versus eukaryotic (mammalian) systems. To this end we have isolated and separately expressed the DNA polymerase subunits encoded by the mucAB and samAB operons. After demonstrating how these enzymes control chemical and UV mutagenesis at the standard hisD3052 and hisG428 Ames test targets, we are now adding the third Ames test target hisG46 to the trilogy.

Results
Four new Ames tester strains based on the hisG46 target have been constructed expressing the activated DNA polymerase MucA’ and SamA’ accessory subunits combined with the MucB and SamB catalytical subunits under the control of lac promoter. These polymerase assemblies were substituted for the endogenous PolRI, PolV and SamAB polymerases present in the standard TA100 strain and tested for their abilities to promote chemically induced mutagenesis. SamA’ + SamB has been able to promote mutagenesis induced by AF-2 and 1,8-DNP to higher extent than SamA’ + MucB. The MucA’ + MucB (PolRI*) more efficiently promoted MMS as well as spontaneous mutagenesis than its wild type counterpart but was less efficient for other mutagens including AFB1. Strikingly azide mutagenesis was inhibited by PolRI and also SamA’B.

Conclusion
A new system for SOS-independent overexpression of the activated DNA polymerases RI and SamA’B and their chimeras in the hisG46 Ames test background has been established and validated with several representative mutagens. Overall, the TA100 strain showed the highest sensitivity towards most tested mutagens. The observed inhibition of azide mutagenesis by PolRI* suggests that this type of Y-family DNA polymerases can perform also “corrective” error free replication on a damaged DNA.
Strategi Pengembangan Industri Kerajinan Eceng Gondok di Kabupaten Semarang
Authors: Fatmawati Fatmawati , Suseno Deky Aji 
Published: March 2020

Industri kerajinan eceng gondok di Kabupaten Semarang sangat potensial untuk dikembangkan, namun perkembangannya mengalami penurunan yang semula di tahun 2013 terdapat 18 unit usaha menurun menjadi 10 unit usaha di tahun 2015. Volume produksi di tahun 2015 juga mengalami penurunan jika dibandingkan dengan tahun 2014. Hal tersebut berbanding terbalik dengan ketersediaan bahan baku eceng gondok di Rawapening yang terus mengalami peningkatan. Sampel dalam penelitian ini terdiri dari 10 perajin dan 8 keyperson. Adapun metode penelitian yang digunakan adalah analisis deskriptif untuk mengetahui permasalahan industri dan Analisis Hierarki Proses (AHP) untuk menentukan strategi pengembangan industri kerajinan eceng gondok di Kabupaten Semarang. Hasil penelitian menunjukkan bahwa permasalahan mendasar yang dihadapi adalah masih terbatasnya SDM yang terampil. Prioritas utama dalam pengembangan industri kerajinan eceng gondok di Kabupaten Semarang adalah kriteria SDM (nilai bobot 0,463), disusul kriteria pemasaran (nilai bobot 0,347), kriteria manajemen produksi (nilai bobot 0,119), dan kriteria teknologi (nilai bobot 0,017). Adapun saran dari penelitian ini antara lain diharapkan pemerintah dan pihak yang berkepentingan lebih memfokuskan pengembangan industri kerajinan eceng gondok melalui peningkatan pengetahuan dan keterampilan teknis SDM melalui pendidikan dan pelatihan.
Water hyacinth crafts industries in Semarang Regency potential for development, but its development has decreased which was originally in the year 2013, there are 18 business units decreased to 10 business units in 2015. The production volume in 2015 also decreased compared to 2014. The inversely proportional to the availability of raw materials in the water hyacinth Rawapening which is constantly increasing. The sample in this study consisted of 10 craftsmen and 8 keyperson. The research method used is descriptive analysis to find out the problems of industries and Analysis Hierarchy Process (AHP) to determine the development strategy of water hyacinth crafts industries in Semarang Regency. The results showed that the fundamental problems faced is the limited skilled human resources. The main priority in the development of water hyacinth crafts industries in Semarang district is HR criteria (weight value 0.463), followed by marketing criteria (weight value 0.347), production management criteria (weight value 0.119), and technology criteria (weight value 0.017). The suggestion from this study are expected in the government and interested parties more focused development of water hyacinth crafts industries by enhancing the knowledge and technical skills of human resources through education and training
Rantai Nilai Cabai di Lahan Pasir Pantai Kabupaten Kulon Progo
Authors: Nugroho Agus Dwi , Prasada I Made Yoga , Putri Saraswati Kirana , Anggrasari Herdiana , Sari Pinjung Nawang 
Published: March 2020

Tujuan penelitian ini adalah mengetahui rantai nilai cabai di lahan pasir pantai Kabupaten Kulon Progo. Penelitian ini dilakukan antara bulan Mei sampai Agustus 2017 di Kecamatan Panjatan, Kabupaten Kulon Progo, Provinsi Daerah Istimewa Yogyakarta. Responden penelitian yakni 30 petani dan pedagang cabai. Hasil penelitian menunjukkan rantai nilai cabai di lahan pasir pantai telah berlangsung dengan baik. Indikator aliran produk, uang dan informasi termasuk dalam kategori lancar dan sangat lancar. Keberhasilan usahatani dan pemasaran cabai di lahan pasir pantai karena keberadaan pasar lelang yang mampu menjamin terjualnya produk dengan harga menguntungkan bagi petani dan pedagang. Salah satu hal yang perlu dikembangkan pasar lelang adalah perlunya kepastian informasi ketersediaan stok cabai dari petani sehingga dapat digunakan sebagai salah satu solusi untuk mengurangi fluktuasi harga cabai. Pasar lelang perlu memperluas jaringan binaan kelompok tani agar ada kontinuitas stok cabai sepanjang tahun.
The value chain needs to be known by farmers or industries to increase value-added and profits of commodities, including chilli in the sandy coastal area. The purpose of this research is to know the value chain of chilli in the sandy coastal area Kulon Progo Regency. This research was conducted between May until August 2017, in Panjatan District, Kulon Progo Regency, Yogyakarta Province. The respondents were 30 farmers and traders. The results showed that the value chain of chilli in the sandy coastal area has been going well. The product, financial and information flow indicators in the smooth and very smooth categories. The success of farming and marketing of chilli in the sandy coastal area because of the existence of the auction market. It’s able to guarantee the sale of chilli with the best price for farmers and traders. To develop the auction market, its need for a certainty the availability of chilli stock from farmers so it can be used as a solution to reduce the fluctuation of chilli’s price. The auction market needs to expand the network of farmer groups to ensure continuity of chilli stock every year.
Valuasi Ekonomi dan Strategi Pengembangan Wisata Alam Pendakian dan Mawar Camp Area
Authors: Furqony Muhammad Izzuddin 
Published: March 2020

Basecamp Mawar Gunung Ungaran adalah salah satu potensi destinasti wisata di Kabupaten Semarang. Tujuan penelitian ini adalah untuk mengidentifikasi variabel apa saja yang mempengaruhi permintaan kunjungan, menghitung valuasi ekonomi melalui pendekatan travel cost dan menentukan strategi yang dapat diterapkan untuk pengembangan Basecamp Mawar. Penelitian ini menggunakan analisis regresi linear berganda, analisis valuasi ekonomi melalui individual travel cost dan analisis SWOT. Hasil menunjukkan variabel akses, motivasi perjalanan dan biaya perjalanan berpengaruh signifikan, sedangkan variabel pendapatan tidak berpengaruh signifikan terhadap permintaan kunjungan Basecamp Mawar. Hasil analisis valuasi ekonomi berdasarkan travel cost pengunjung menunjukkan bahwa valuasi ekonomi total sebesar Rp 8.212.546.988,73 per tahun. Analisis strategi menggunakan SWOT menunjukkan bahwa strategi yang dapat diterapkan adalah meningkatkan fasilitas dan pelayanan, menjaga dan melestarikan alam, promosi dan kerjasama dengan pihak swasta dan pemerintah.
Basecamp Mawar Gunung Ungaran is one of the potential tourist destinations in Semarang regency. The purpose of this study is to identify what variables affect the demand of visits, calculate the economic valuations through the travel cost approach and determine the strategies that can be applied to the development of Rose Basecamp. This study uses multiple linear regression analysis, economic valuation analysis through individual travel cost and SWOT analysis. The result shows that access variables, travel motivation and travel cost have significant effect, while income variable has no significant effect to the request of Basecamp Mawar visit. The result of economic valuation analysis based on travel cost of visitors shows that the total economic valuation is Rp 8,212,546,988,73 per year. Strategy analysis using SWOT shows that the strategies that can be applied are improving facilities and services, preserving and preserving nature, promotion and cooperation with private and government parties.
Fiscal Decentralization and Regional Economic Growth
Authors: Sasana Hadi 
Published: March 2020

Fiscal decentralization in Indonesia initiated in 2001 has proven to be effective and efficient; although, its implementation still need to be evaluated. The aim of the study was to analyze the implementation of fiscal decentralization on economic growth in Central Java. Tools multiple regression analysis using the method Fixed Effect Model (FEM).The period of the research was 9 years (2009-2017), and the subject of the was 35 districts/cities in Central Java Province. The dependent variable was economic growth, the independent variable was fiscal decentralization, and the control variables were investment and labor. The results showed that fiscal decentralization has a positive effect on economic growth in the district/city in Central Java. Other findings, private investment and the amount of labor encourage economic growth in Central Java. Based on findings, to reduce the fiscal gap, local governments should be able to increase their fiscal capacity through the development of commodity-based economic activity in their regions
Keywords: Fiscal decentralization, Economic growth, Investment, Labor
The Influence of Marketing and Production Factor on Troso Weaving Cloth
Authors: Setiaji Khasan , Umi Rifalatul 
Published: March 2020

The business performance is influenced by various factors such as marketing strategy and production factor. Both have important roles to improve business performance. However, the number of Troso weaving cloth decreased gradually from 2013 up to 2016. This study aims at knowing the impact of marketing strategy and production factor to the performance of small and medium enterprises on Troso weaving cloth simultaneously and partially. The population was 180 owners of Troso weaving cloth with the sample of 64. The sample was determined by using proportionate random sampling. Then, the variables for this study consist of independent variables that are marketing strategy (X1) and production (X2) factor; and dependent variable that is business performance (Y). Based on the percentage descriptive analysis. The marketing strategy variable has influence as many as 73% with good category, while the production factor influences business performance, 61% with the moderate category. This study has found that marketing strategy and production factor have positive and significant impact partially and simultaneously to the business performance of small and medium enterprises on Troso weaving cloth.
Analysis of Willingness to Pay (WTP) at Vocational High School
Authors: Susanti Anik , Nihayah Dyah Maya 
Published: March 2020

The purpose of this study is to estimate and analyze the willingness to pay (willingness to pay) and fax tor the factors that affect the willingness to pay at Vocational High School in the of Semarang. The method used is Contingent Valuation Method (CVM) and multiple linear regression analysis. The number of samples in this study were 100 respondents, the sampling technique was done by purposive sampling and proportional sampling. The results of this study indicate that the average willingness to pay (WTP) of households in Vocational High Schools in Semarang is Rp. 167.950,00. Factors that have a significant influence on WTP values ​​are income variables, number of household dependents, age and length of access. Whereas the factors that have no effect on willingness to pay (WTP) are parents' education variables. Based on the results of the study, the suggestions that can be put forward are the management or the government to improve the quality of the Vocational School as well as the development of a transparency policy on the collection and allocation of user fees and other resources
Projections of Regional Macroeconomic Conditions using the Univariate Forecasting Method
Authors: Dwiputri Inayati Nuraini , Kusufi Muhammad Syam , Allo Albertus Girik 
Published: March 2020

The prediction of future macroeconomic conditions is needed by the government to carry out the planning and budgeting. This study predicts macro indicators in Hulu Sungai Utara Regency in the period 2017-2022. The method used is univariateforecasting, which includes the ARIMA model, exponential smoothing, and exponential smoothing with trend adjustment. The macroeconomic indicators used in this study are real Gross Domestic Regional Product (GDRP), economic growth, unemployment rate, and income distribution. The results of the analysis show that Brown's forecasting model is predicted that the real GDRP value tends to increase, forecasting results using a simple model on economic growth and the ARIMA (0.0,0) model on the unemployment rate, had predicted tends to be constant. And, the prediction of income distribution with the Holt model tends to increase.
Keywords: macroeconomic, univariate, forecasting, ARIMA, exponential smoothing
JEL Classification: E0, O1, C0