bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical identification of 18-hydroxycarlactonoic acid as an LjMAX1 product and conversion of 18-hydroxylcarlactonoates to canonical and non-canonical strigolactones in Lotus japonicus
Authors: Mori Narumi , Sado Aika , Xie Xiaonan , Yoneyama Kaori , Asami Kei , Seto Yoshiya , Nomura Takahito , Yamaguchi Shinjiro , Yoneyama Koichi , Akiyama Kohki 
Published: November 2019

AbstractStrigolactones (SLs) are a group of plant apocarotenoids that act as rhizosphere signaling molecules for both arbuscular mycorrhizal fungi and root parasitic plants. They also regulate plant architecture as phytohormones. The model legume Lotus japonicus produces canonical 5-deoxystrigol (5DS) and non-canonical lotuslactone (LL). The biosynthesis pathways of the two SLs remain elusive. In this study, we characterized the L. japonicus MAX1 homolog, LjMAX1, found in the Lotus japonicus genome assembly build 2.5. The L. japonicus max1 LORE1 insertion mutant was deficient in 5DS and LL production. A recombinant LjMAX1 protein expressed in yeast microsomes converted carlactone (CL) to 18-hydroxycarlactonoic acid (18-HO-CLA) via carlactonoic acid (CLA). Identity of 18-HO-CLA was confirmed by comparison of the methyl ester derivative of the MAX1 product with the chemically synthesized methyl 18-hydroycarlactonoate (18-HO-MeCLA) using LC-MS/MS. (11R)-CL was detected as an endogenous compound in the root of L. japonicus.13C-labeled CL, CLA, and 18-HO-MeCLA were converted to [13C]-5DS and LL in plant feeding experiments using L. japonicus WT. These results showed that LjMAX1 is the crucial enzyme in the biosynthesis of Lotus SLs and that 18-hydroxylated carlactonoates are precursors for SL biosynthesis in L. japonicus.
ClinCNV: novel method for allele-specific somatic copy-number alterations detection
Authors: Demidov German , Ossowski Stephan 
Published: November 2019

AbstractMotivationLarge somatic copy number alterations (CNA), short indels and single nucleotide variants (SNVs) are playing important role in cancer development and can serve as a predictor for targeted therapy selection as well as prognostic factor. Genomic microarrays, FISH, MLPA and many other technologies are widely used for detection of CNAs. Whole-genome sequencing (WGS), whole-exome sequencing (WES) and targeted panel sequencing (TPS) are well established, highly accurate tools for detection of SNVs and small indels, but detection of larger structural variants using WGS, WES and TPS data remains challenging. We developed a tool for high-resolution allele-specific detection of somatic CNAs in NGS data using statistical approach.ResultsWe have developed a new method for read-depth and B-allele frequency (BAF) based multi-sample detection of copy-number changes in paired normal-tumor NGS data and showed its performance using large cohorts of WES and TPS sequenced samples.AvailabilityClinCNV is freely available on https://github.com/imgag/ClinCNV.
Systematized literature review on financial inclusion and exclusion in developed countries
Authors: Fernández-Olit Beatriz , Martín Martín José María , Porras González Eva 
Published: November 2019

Purpose
The purpose of this paper is to provide a systematic literature review of the research published on financial inclusion (FI) and financial exclusion (FE) in developed countries using key terms and strict inclusion and exclusion criteria.

Design/methodology/approach
In total, 52 papers were deemed to be relevant to the analysis. These works were critiqued using a framework that addressed geographical contexts, topics, methodologies and theoretical frameworks.

Findings
This review highlights the uneven level of development of the academic debate between North America, the UK and continental Europe, and identifies the different theoretical frameworks that construe the body of literature in each region. In addition, the findings show the scant offer of work on the impact that the digital economy has on FE, as well as the reduced number of studies which have focused on certain vulnerable groups and the access to some financial services.

Social implications
The studies reviewed have not analyzed the specific needs of vulnerable groups while considering the different contexts and pathways to exclusion. The evaluation of solutions and strategies to achieve inclusion is one of the least addressed aspects in the literature.

Originality/value
The paper synthesizes the main contributions of the top literature on the redefinition of FI/FE in developed countries, the role of fringe services and new determinants of exclusion. The proliferation of studies regarding FI in low- and middle-income countries has generated a great amount of meta-analysis and systematized reviews of asymmetric results. However, no systematized literature review on the broad scope of FI/FE in developed countries has been published in the last decade. This work sheds light over poorly analyzed areas of research that refer to notable social problems.
The “dark side” of organisational career growth
Authors: Spagnoli Paola , Lo Presti Alessandro , Buono Carmela 
Published: November 2019

Purpose
The purpose of this paper is to investigate the role of organisational career growth (OCG) in the process linking organisational work–family support and work–family conflict.

Design/methodology/approach
Since previous contributions reported theoretical and empirical evidence of possible gender differences in this process, a moderated mediation model was examined including gender as moderating variable of both direct and indirect effects. Conditional process analysis was used to test the hypotheses on a sample of 507 Italian employees who were also parents.

Findings
Results showed a significant mediation effect of OCG in the relationship between organisational work–family support and work–family conflict. Furthermore, evidence of a moderated effect of gender was found in the way that the negative direct effect of organisational work–family support on work–family conflict was stronger among women, whereas the direct effect of OCG on work–family conflict was significant only for men.

Originality/value
This is the first study addressing the possible negative effect of OCG on a specific target of employees.
Investigating visitors’ perception of smart city dimensions for city branding in Hong Kong
Authors: Chan Chung Shing , Peters Mike , Pikkemaat Birgit 
Published: November 2019

PurposeThe purpose of this paper is to understand the perceptions of visitors in terms of multiple aspects of smart cities to allow wise decisions to be made about smart tourist destinations by municipal governments and tourism authorities.Design/methodology/approachThis study takes a sample of inbound visitors (n=205) from Hong Kong as an empirical questionnaire-based survey on visitors’ perceptions of these smart city attributes, which are collected from literature, and framed in Cohen’s Smart City Wheel.FindingsThis paper identifies the distinctive factors for branding Hong Kong as a smart city. The results from the factor analysis identify four factors for determining what a smart city is from the perspective of visitors, namely, the quality of a smart society: energy consumption in an urban environment, smart city governance and smart city livelihood. The first two factors further become the determinants of a successful smart city brand considered by visitors, which contribute to their locational decisions and thus the strategies and policies of smart destination branding.Research limitations/implicationsThe results obtained can serve as insights for tourism policy makers and destination marketers when considering significant information and communication technology, or other smart and sustainable attributes for city branding (e.g. Buhalis and Amaranggana, 2014; Marine-Roig and Anton Clavé, 2015), as well as common investment and resource allocation for shared benefits in similar metropolises.Practical implicationsThe smartness factors represent important dimensions of urban smartness as prioritized areas for further development, innovation and marketing of tourism industries and enterprises in Hong Kong, as a mature urban destination incorporating the branding of a proposed smart district as a strategy of urban development.Originality/valueSmart urban development and tourism development have increasingly become inseparable, especially when visitors utilize cities as tourist destinations but share other urban resources and spaces with local citizens. Unlike the development of smart tourist attractions, smart tourist destinations should have a wider scope of smartness. A smart tourist destination may carry similar and overlapping characteristics of smart cities, which may be interpreted by visitors and may eventually affect their perceived image of a city.
Collaborative inquiry play
Authors: Saleh Asmalina , Hmelo-Silver Cindy E. , Glazewski Krista D. , Mott Bradford , Chen Yuxin , Rowe Jonathan P. , Lester James C. 
Published: November 2019

PurposeThis paper aims to present a model of collaborative inquiry play: rule-based imaginary situations that provide challenging problems and support agentic multiplayer interactions (c.f., Vygotsky, 1967; Salen and Zimmerman, 2003). Drawing on problem-based learning (PBL, Hmelo-Silver, 2004), this paper provides a design case to articulate the relationship between the design goals and the game-based learning environment.Design/methodology/approachDrawing on conjecture mapping (Sandoval, 2014), this paper presents an iterative development of the conjecture map forcrystal island: ecojourneysand highlights the development of the story and tools incrystal island: ecojourneys, an immersive game based on PBL pedagogy. By articulating this development, the authors highlight the affordances and constraints of designing for collaborative inquiry play and address challenges in supporting learner agency.FindingsThe PBL inquiry process served as the foundation of collaborative inquiry play. Attending to the rules of inquiry fostered student agency, and in turn, playful engagement in the game-based learning environment. Agency however meant holding students accountable to actions undertaken, especially as it pertained to generating group-based explanations and reflecting on productive collaboration. Moreover, socially shared regulation of learning and systems thinking concepts (i.e. phenomenon, mechanisms, and components) must also be externalized in representations and interactions in the game such that students have the agency to decide on their learning paths.Originality/valueThis paper presents the model of collaborative inquiry play and highlights how to support player agency and design content-rich play environments which are not always completely open.
Psychological factors affecting the behavioral intention of the tourist visiting Southeastern Anatolia
Authors: Çelik Sedat , Dedeoğlu Bekir Bora 
Published: November 2019

PurposeThe purpose of this paper is to reveal the relationship between personality traits, travel motivations, perceived destination quality, overall destination satisfaction and behavioral intentions of domestic tourists.Design/methodology/approachThe quantitative research method was used in the study. A survey technique was used to collect data. Data were applied to incoming domestic tourist to Gaziantep and Sanliurfa cities in Southeast Anatolia of Turkey. The data obtained were analyzed by structural equation modeling.FindingsThe study showed that personal traits “agreeableness” and “conscientiousness” positively affect relaxation motivation. Cultural and relaxation motivations had a positive impact on satisfaction, whereas pleasure-seeking motivation has a negative impact on satisfaction. In addition, overall destination satisfaction is positively affected by destination quality perceptions and affects loyalty in a positive way.Research limitations/implicationsDuring the literature review phase, no scale was found according to different destination characteristics (cultural, nature and sea destinations). In this regard, developing new scales to measure destination quality in accordance with different destination types would allow comprehending the subject in a more clear and detailed way.Practical implicationsThe establishment of relationship between variable examined by this study ensures that product and services provided by the destination reach the correct target audience, which brings along the success to destination. For instance, destination management organizations could get information from travel agencies they work with about the characteristics, and motivations of tourists, and could develop their strategies, and plans, accordingly.Originality/valueThis study has three important contributions. First, revealing the role of personality in tourist behavior; second, their behaviors and attitude before (motivation and personality) during (destination quality and satisfaction) and after visiting (behavioral intentions) were examined; and third, personality, travel motivation, destination quality and satisfaction are discussed together as a model in this study.
Empirical assessment of mobile device users’ information security behavior towards data breach
Authors: Giwah Anthony Duke , Wang Ling , Levy Yair , Hur Inkyoung 
Published: November 2019

Purpose
The purpose of this paper is to investigate the information security behavior of mobile device users in the context of data breach. Much of the previous research done in user information security behavior have been in broad contexts, therefore creating needs of research that focuses on specific emerging technologies and trends such as mobile technology.

Design/methodology/approach
This study was an empirical study that gathered survey data from 390 mobile users. Delphi study and pilot study were conducted prior to the main survey study. Partial Least Square Structural Equation Modeling was used to analyze the survey data after conducting pre-analysis data screening.

Findings
This study shows that information security training programs must be designed by practitioners to target the mobile self-efficacy (MSE) of device users. It also reveals that practitioners must design mobile device management systems along with processes and procedures that guides users to take practical steps at protecting their devices. This study shows the high impact of MSE on users’ protection motivation (PM) to protect their mobile devices. Additionally, this study reveals that the PM of users influences their usage of mobile device security.

Originality/value
This study makes theoretical contributions to the existing information security literature. It confirms PM theory’s power to predict user behavior within the context of mobile device security usage. Additionally, this study investigates mobile users’ actual security usage. Thus, it goes beyond users’ intention.
Quick start guide: how to review teaching cases
Authors: Foster Mary Kuchta 
Published: November 2019

Theoretical basis
Metacognition, learning how to learn, peer feedback and peer review.

Research methodology
Essay based on experience as a reviewer and editor and best practices.

Case overview/synopsis
This quick start guide provides a tutorial on how to review teaching cases and the associated instructor’s manual or teaching note. The purpose of this guide is to help develop the confidence and skill of novice reviewers and refresh and refocus experienced reviewers. Case writers may also use this guide to anticipate peer reviewer feedback and assess or refine their cases before submitting them to a journal. Reviewing is essential to the Academy – without peer reviews there would be no peer reviewed journal articles, a pillar of the tenure process. Reviewing is also a valuable way to learn, to keep current in a field and to be a good citizen – contributing to one’s professional community. This guide will help scholars become even more effective reviewers, writers and contributors to the Academy.

Complexity academic level
For academics interested in developing their case reviewing skills.
Exploring the relationship between resilience and practice education placement success in occupational therapy students
Authors: Brown Ted , Yu Mong‐Lin , Hewitt Alana E. , Isbel Stephen T. , Bevitt Thomas , Etherington Jamie 
Published: November 2019

AbstractIntroductionPractice education is a fundamental component of health professional students’ education and many personal, social and professional factors impact on students’ performance. This study investigated the relationship between measures of resilience and practice education performance in occupational therapy students.MethodsA quantitative cross‐sectional study was used to collect the data. In all, 149 occupational therapy students completed a self‐report questionnaire comprised of demographic questions and two standardised scales: Resilience at University (RAU) and Resilience Scale for Adults (RSA). Students’ practice education performance was measured by the Student Practice Evaluation Form–Revised (SPEF–R). Multi‐linear regression analyses with bootstrapping were completed to identify resilience factors that were predictive of occupational therapy students’ practice performance.ResultsOverall, occupational therapy students reported high levels of resilience based on the RAU and RSA subscale scores. “Managing Stress,” “Find Your Calling” and “Living Authentically” were strong predictors of a range of key fieldwork performance SPEF–R factors, including “Professional Behaviours,” “Self‐management Skills,” “Co‐worker Communication” and “Communication Skills.”ConclusionThe resilience factors identified as being significant predictors of practice education performance outcomes in occupational therapy students represent notable findings. They suggest that students’ capabilities in managing their stress levels, finding meaning in their chosen profession, and engaging self‐care daily activities outside of the work environment that are meaningful, authentic and fit with one's personal values and beliefs can act as buffers against the challenges experienced by students who are completing practice education placements. The findings will assist academic and practice educators in identifying and targeting vulnerable students and strengthening resilience strategies through proactive pre‐practice placement initiatives. Qualitative studies are recommended to further explore the relationship between resilience and practice education performance in occupational therapy students.
Diversity of foliicolous lichens in isolated montane rainforests (Brejos) of northeastern Brazil and their biogeography in a neotropical context
Authors: Santos Viviane M. , da Silva Cáceres Marcela E. , Lücking Robert 
Published: November 2019

AbstractFoliicolous lichenized fungi (FLF) are widely distributed in tropical forests. The Brazilian Atlantic rainforest, one of the most diverse rainforest biomes, has multiple phyto‐physiognomies. Montane forest fragments or forest refuges, so‐called “Brejos,” are located within the semiarid Caatinga in Northeast Brazil. Our objective was to determine the FLF diversity within five Brejos and to analyze their biogeographic affinities within the Neotropics. The FLF biota of the Brejos was compared with that of 21 sites belonging to seven other rainforest biomes, ranging from the Atlantic rainforest in Argentina, to montane rainforests in Ecuador, to the Amazonia basin, and rainforests in Central America. One hundred and fifty‐six species were identified in the Brejos. This biota is most similar to that of the Atlantic rainforest and eastern Amazonia, while that of western Amazonia is more similar to that of the Andes and rainforests in Central America (Chocó). Multiple species identified in the Brejos have a wide distribution in tropical America, and only 11 are potentially endemic. Few other species have also a restricted distribution. The FLF biota of the Chocó and western Amazon is substantially richer than that of eastern Amazon, the Atlantic rainforest and the Brejos. This suggests that the biota of the latter areas is largely a depauperate subset of the Chocó and the western Amazon region. We argue that the major differences between the two large regions are related to the Pleistocene and Pliocene, when paleoclimatic and geological changes caused the isolation of the Brejos and the temporary fragmentation particularly of eastern Amazonia.
Food Brexit and Chlorinated Chicken: A Microcosm of Wider Food Problems
Authors: Millstone Erik , Lang Tim , Marsden Terry 
Published: November 2019

AbstractThis paper situates food safety concerns raised in the Brexit debate since the referendum and suggests that, although the issue of chlorinated chicken entered public discourse, it represents wider concerns about food safety standards. Food safety has had high resonance in the UK since the 1980s, but Brexit shows how it connects to wider concerns also raised about Brexit, such as impacts on healthcare, the effects of austerity on food poverty, the limitations of low waged employment, concerns about migration and labour markets, and regional economic disparities. Brexit’s impact on the UK food system is immense because food has been highly integrated into EU governance. While food standards can be portrayed as a single narrow issue, the paper suggests it provides a useful lens with which to examine, interrogate and comprehend these wider Brexit politics. The complex realities of food politics and wider food system dynamics undermine any simplistic political narrative of ‘taking back control’.
Examining mechanisms for gender differences in admission to intensive care units
Authors: Hill Andrea , Ramsey Clare , Dodek Peter , Kozek Jean , Fransoo Randy , Fowler Robert , Doupe Malcolm , Wong Hubert , Scales Damon , Garland Allan 
Published: November 2019

AbstractObjectiveTo evaluate whether the male predominance of older people admitted to intensive care units (ICUs) is due to gender differences in the presence of spouses, partners, or children; rates of gender‐specific disease; or triage decisions made by health system personnel.Data Sources and CollectionThree population‐based datasets, 2004‐2012, of Canadians ≥65 years: provincial health care data from Manitoba (n = 250 190) and national data of nursing home residents (n = 133 982) and community‐based homecare recipients (n = 210 090).Study DesignRetrospective observational study, using multivariable Cox proportional hazards and logistic regression.Principal FindingsMales predominated in ICU admissions: from Manitoba (hazard ratio [HR] = 1.87, 95% CI = 1.80‐1.95), nursing homes (HR = 1.47, 1.35‐1.60), and homecare (odds ratio = 1.14, 1.11‐1.17). Adjustment for spouses, partners, and children did not attenuate this effect. The HR for gender was lower by 13.5 percent, relative, after excluding ICU care for cardiac causes. Male predominance was not present during a second ICU admission among survivors of a first ICU‐containing hospitalization (HR = 1.07, 0.96‐1.20).ConclusionsIn three older cohorts, the male predominance of ICU admission was not explained by gender differences in the presence of a spouse, partner, or children, or cardiac disease rates. The third finding suggests that triage bias is unlikely to be responsible for the male predominance.