bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lipid-Based Nanosystem As Intelligent Carriers for Versatile Drug Delivery Applications
Authors: Harshita  , Barkat Md. Abul , Das Sabya S. , Pottoo Faheem H. , Beg Sarwar , Rahman Ziyaur 
Published: February 2020

:The contemporary drug discovery research shows that most of the drug candidates are highly potent, but showing poor aqueous solubility leads a variety of challenges for formulation scientists to develop a suitable formulation to improve the systemic bioavailability of such drugs. Lipid-based nanocarriers act as a major and most projecting approach overcoming the limitations which affect several physiochemical properties of drug such as the solubility, partition coefficient and bioavailability or absorption. This also fulfills a variety of product requirements and helps to overcome several limitations as decided by symptoms of the disease, various routes of administration of drug, price concern, increasing strength of product, noxious or harmful effect of drug, and dose efficacy. The lipidic nanosystem formulates aqueous drug in lipid base and is also a commercially feasible approach for the formulation of different dosage forms meant for topical or transdermal, oral, ocular, pulmonary, and parenteral delivery. This review provides a brief on lipid-based drug delivery nanocarrier and the mechanisms by which lipids and lipidic excipients improve the oral absorption of drugs with poor aqueous solubility and also provide a viewpoint on the promising applications of lipidic nanoparticulate systems.
Use of Social Media at Cardiovascular Congresses: Opportunities for Education and Dissemination
Authors: Mihailidou Anastashia S. , McCall Debbe , Hiremath Swapnil , Costello Briana , Tunuguntla Anuradha , Mihailidis Harris 
Published: February 2020

:
Social Media includes different forms of online communication from Twitter, Facebook,
Instagram, LinkedIn, podcasts, YouTube etc. and has advanced how information is exchanged. A
notable use is engaging on Twitter at medical conferences, both for those attending the conference
and the global audience who are not able to attend. It is also increasingly used as an educational
tool similar to e-learning. The objective of this paper is to: 1) highlight the impact of using Twitter
at cardiovascular congresses as an interactive platform for active learning as compared to passively
listening to a presentation; 2) present perspectives from not only clinicians, researchers but also patients
on how this information is interpreted; 3) provide recommendations for conference organizers
for best practice live tweeting to share the information and knowledge beyond those in attendance;
with potential for not only engagement but also educating our global community.
Risk Factors and Management of Kidney Diseases in Saudi Women with Diabetes
Authors: Siddiqui Khalid , Joy Salini Scaria 
Published: February 2020

Background:The prevalence of diabetic kidney diseases (DKD) in the Saudi population is increasing and its prevalence has been reported as 37.4%. Recently, a higher prevalence of albuminuria in women has been proven through population-based studies.Objectives:Recently, the Kingdom of Saudi Arabia (KSA) has witnessed many changes in women’s activities, and women are more actively participating in the social and cultural development of the country. Thus, focusing on women’s health-related issues has become crucial. The necessity of research focusing on the influence of various risk factors on DKD has emerged as a priority.Methods:The literature search was done by search engines and databases (PubMed, Google scholar and EMBASE). From a total of 21 selected articles, 18 articles are included in this study.Results:This review emphasizes on the higher influence of certain DKD risk factors on Saudi women including a high prevalence of glucose intolerance during pregnancy, obesity due to lack of physical activity, and genetic predisposition due to consanguineous marriages, etc.Conclusion:This study can raise awareness regarding the prevention and management of DKD in Saudi diabetic women.
Evaluation of Radiolucent Lesions Associated with Impacted Teeth: A Retrospective Study
Authors: Karabas Hulya Cakir , Ozcan Ilknur , Tekkesin Merva Soluk , Tasyapan Sedef Ayse , Guray Beliz , Atapek Murat Mert 
Published: February 2020

Background:
Impacted teeth are commonly asymptomatic and not associated with any
pathologic lesions for years. Any change in the size of the follicle associated with impacted teeth
may result in odontogenic cysts or tumors. CBCT plays an important role in determining the radiographic
features of a lesion and therefore, is very helpful for accurate diagnosis and treatment
planning.

Objective:
This study aims to evaluate radiolucent lesions associated with impacted teeth in terms
of age and sex distribution, localization, and comparison with the pathological diagnosis.

Methods:
In this retrospective study, out of 6758 CBCT images, 400 images revealing radiolucent
lesions were detected. The study included only 190 cases (regarding 180 patients) which had a
matching histopathological evaluation. Data related to the age and sex of the patients, localization
of the lesions, and their comparison with the pathological diagnosis were recorded and analyzed.

Results:
The most encountered lesions were dentigerous cysts (60%) and odontogenic keratocysts
(26.3%). Males were the most affected (63.3%). Most of the lesions were found in the left and
right posterior mandible and mostly (66.8 %) associated with third molars. Out of 123 radiological
diagnoses of dentigerous cyst cases, histopathological diagnoses confirmed 108 cases. Regarding
odontogenic keratocyst, histopathological diagnosis confirmed 40 cases out of 48.

Conclusion:
Radiological diagnoses of the lesions mostly match with their pathological diagnosis
unless their characteristics are changed due to infection. CBCT, as a technique enabling detailed
imaging of the involved dental structures, is a helpful instrument for differential diagnosis.
Experimental Investigation of the Bullet-proof Properties of Different Kevlar, Comparing .22 Inch with 9 mm Projectiles
Authors: Stopforth Riaan , Adali Sarp 
Published: February 2020

Background:
Results of an experimental study are given involving high-impact
ballistic tests using .22 inch diameter ammunition (commonly known only as .22 ammunition)
with the target set up as a combination of different numbers and weights of Kevlar layers.
These experimental tests are conducted as literature indicating that the .22 projectiles are
not as effective as with larger calibre ammunition. Present work is part of a research study to
assess the safety limits of Kevlar layers of different weights against various calibre projectiles.

Objective:
The objective is to obtain test data to determine the number of Kevlar layers and
weights needed for the design of safe bullet proof vests capable of stopping various size
ammunition. In the present study, results are given for .22 inch ammunition, which provide
data on the characteristics of high-speed ballistic penetration of .22 bullets into Kevlar layers
and stopping distances in gel/Kevlar combinations.

Methods:
Tests were performed with Kevlar fabrics of different weights of Gram per Square
Meter (GSM) to provide a comparison among different Kevlar fabrics as well as with different
number of Kevlar layers. The tests were conducted with the use of a chronograph in a
controlled test environment. The penetration depth in ballistic gelatine was recorded.

Results:
The results identify the number of layers of Kevlar required to stop a .22 projectile
and the relationship between the different layers and weights of Kevlar materials. The results
of the .22 projectile penetration are compared with those of different 9 mm Parabellum
projectiles to assess the effect of different size ammunition on the bullet-proof capabilities of
Kevlar. Experimental data on the penetration depths of different types of bullets into the
gel/Kevlar combinations are presented using various graphs.

Conclusion:
The .22 projectiles perform similar penetration depths compared to that of
9 mm projectiles, and therefore cannot be considered as ineffective ammunition as literature
has indicated.
Penggunaan Metode Ontology Untuk Perancangan Purwarupa Sistem Smart Home Berbasis Context Aware
Authors: Perdana Guntur , Ashari Ahmad 
Published: February 2020

Smart home system is a computer-aided system that will provide all comfort, safety, security and energy savings, which works automatically and programmed through a computer in a building or home. One of the method that can be used to design smart home is context aware method. Context aware can work with the help of several other methods such as ontology method. Ontology has a variety of definition and always changes time by time. Ontology method is one of method that can process complex data. The ontology method allows complex reasoning and representation with better results. Constraints that are often encountered when designing a system that looks complex will face many problems such as many ambiguous domains. The existence of an ontology design before carrying out the prototype design of the smart home system will facilitate the smart home design process especially if the system will be made more complex so it would allows ambiguity from multiple domains. Testing with this ontology method is effective enough to minimize ambiguity from each domain, because each domain is designed with different characteristics. The results of the test concluded that the ontology design can be realized as a prototype of the smart home system.
Topic Modeling the Hàn diăn Ancient Classics (汉典古籍)
Authors: Allen Colin , Luo Hongliang , Murdock Jaimie , Pu Jianghuai , Wang Xiaohong , Zhai Yanjie , Zhao Kun 
Published: February 2020

There is a small but growing literature on large-scale statistical modeling of Chinese language texts. Ouyang analyzed a corpus of over 40,000 ancient documents downloaded from multiple sources. This was used to plot the temporal distributions of word frequencies and geographic distributions of authors. Huang and Yu modeled the SongCi poetry corpus, first converting it to tonally marked pinyin to conserve poetically important pronunciation information. Nichols and colleagues reported initial modeling of the Chinese Text Project corpus1 in a conference paper. (Further below, we describe differences between this corpus and the Handian.) With additional collaborators, this group has now conducted two studies that are currently unpublished but under review. In the first, they apply topic models to address scholarly questions about the relationships among important texts of Ancient Chinese philosophy. In the second, they use topic modeling to investigate the concepts of mind and body in ancient Chinese philosophy. Although we share similar scholarly objectives with these researchers, our approach in this paper is unique in that for the first time anywhere we bring the benefits of computational modeling of ancient Chinese texts to a robust public platform that is mirrored on both sides of the Pacific. Besides being just a useful portal to the texts, our approach foregrounds the interpretive issues surrounding topic models, and makes more sophisticated exploration and analysis of interpretive questions possible for experts and novices alike.
El enfoque de química verde en la investigación en didáctica de las ciencias experimentales. Su abordaje en revistas iberoamericanas: 2002-2018
Authors: Franco Moreno Ricardo Andrés , Ordoñez Carlosama Leydi Yurani 
Published: February 2020

<p>En este artículo se comunican los resultados de una investigación documental orientada al análisis de la producción escrita en el área de la denominada química verde enfocada a la investigación en didáctica de las ciencias experimentales en el ámbito iberoamericano durante el periodo 2002-2018, con base en criterios cienciométricos, identificando proyectos, propuestas y tendencias generales para la vinculación de este enfoque en la educación química. Puede afirmarse que en los últimos 15 años la publicación de artículos sobre química verde en revistas especializadas en didáctica de las ciencias representa un aspecto de la innovación didáctica, producción que se incrementó durante los últimos 5 años, poniendo de presente que esta disciplina transversal de la química, hoy convoca el interés de la comunidad de especialistas en didáctica de la química.</p>
Sanitasi dan Dampaknya bagi Kesehatan: Studi dari Pesantren
Authors: Fahham Achmad Muchaddam 
Published: February 2020

According to the United Nations, sanitation is one of the basic human rights. Sanitation impacts the quality of human life, including in Islamic boarding schools - institutions that organized Islamic religious education. The Islamic boarding houses should meet the sanitation standard to create a conducive environment for the students. This study was conducted using a qualitative method to determine sanitation conditions of Islamic boarding school, the impact of sanitation on the school to students' health conditions, and government policies on sanitation problems faced by the boarding school. Data collection were conducted using in-depth interviews and literature studies, which then analyzed by reducing techniques and drawing conclusions. The study concluded that most Islamic boarding schools in various regions in Indonesia do not have sanitation that met health standards. These conditions have an impact on the health of the students. Many of them have been exposed to scabies, diarrhea, and there were students who have been affected by ARI. There are two government policies implemented to help Islamic boarding schools dealing with sanitation problems: boarding schools health program of the ministry of health and eco-pesantren program of the ministry of environment. However, not all Islamic boarding school have access to any one of these programs. Thus, the government needs to expand the coverage of the boarding school health program and eco-pesantren program. Menurut Perserikatan Bangsa-Bangsa sanitasi merupakan salah satu hak asasi manusia. Sanitasi memengaruhi kualitas hidup manusia, termasuk di pesantren yang merupakan institusi penyelenggaran pendidikan keagamaan Islam. Di pondok tempat tinggal santri seyogyanya memenuhi standar sanitasi agar santri dapat beraktivitas dengan nyaman sesuai dengan tuntunan Islam. Studi ini dilakukan dengan metode kualitatif untuk mengetahui kondisi sanitasi pesantren, dampak sanitasi pesantren terhadap kesehatan santri, dan kebijakan pemerintah terhadap masalah sanitasi yang dihadapi oleh pesantren. Pengumpulan data dilakukan dengan wawancara mendalam dan studi literatur, yang kemudian dianalisis dengan teknik reduksi dan penarikan kesimpulan. Studi ini menyimpulkan bahwa sebagian besar pesantren di berbagai wilayah di Indonesia belum memiliki sanitasi yang memenuhi syarat kesehatan. Kondisi sanitasi yang belum memenuhi syarat kesehatan tersebut memiliki dampak bagi kesehatan santri. Banyak santri yang pernah terkena skabies, diare, dan Infeksi Saluran Pernapasan Akut (ISPA). Ada dua kebijakan pemerintah yang dilaksanakan untuk membantu pesantren keluar dari masalah sanitasi yang dihadapinya, yakni Pos Kesehatan Pesantren dari Kementerian Kesehatan dan eco-pesantren Kementerian Lingkungan Hidup dan Kehutanan. Namun, belum semua pesantren dapat mengakses salah satu kebijakan tersebut. Untuk itu, Pemerintah perlu meningkatkan jangkauan program pos kesehatan pesantren dan eco-pesantren.
Ground beetles (Carabidae) of field margin habitats
Authors: Bennewicz Janina , Barczak Tadeusz 
Published: February 2020

AbstractThe aim of this study was to identify the role of field margin habitats in preserving the diversity and abundance of ground beetle assemblages, including potentially entomophagous species and those with conservation status in Poland.Research material was collected in 2006–2007 in four types of margin habitats – a forest, bushes, ditches and in two arable fields. Insects were captured into pitfalls, without preservation liquid or bait added to the traps.Traps were inspected twice a week, between May and August, and one sample was a weekly capture.In field margin habitats the most abundant species wereLimodromus assimilis,Anchomenus dorsalis,Pterostichus melanariusandCarabus auratus. A lower abundance of species was noted on fields, with dominantPoecilus cupreusandP. melanarius. The group of zoophagous carabids found in our study includes 30 species from field margin habitats, i.e. 37.5% of all captured Carabidae taxa and 58.3% of all specimens. The share of aphidophagous species was 84.9% among bushes, 86.7% near ditches, and 88.0% in the forest habitat. Several species captured during the study are under protection in Poland. These include the partly protectedCarabus convexus, which also has the status of near threatened species, the partly protectedCalosoma auropunctatum, andBroscus cephalotes. Considering all the investigated field margin habitats, ground beetles were most numerous in the oak-hornbeam habitat, defined as bushes, formed predominantly byPrunus spinosa,Crataegus leavigata,Sambucus nigraandRosa canina. Thus, this habitat was the most important reservoir/refugium for the ground beetles.
Pengaruh Struktur Aset, Profitabilitas, Kebijakan Dividen, Pertumbuhan Perusahaan dan Ukuran Perusahaan Terhadap Kebijakan Hutang pada Perusahaan Perbankan yang Listing di BEI Tahun 2015-2018
Authors: Prabowo Ricky Yulianto , Rahmatika Dien Noviany , Mubarok Abdulloh 
Published: February 2020

Penelitian ini bertujuan untuk mengetahui pengaruh struktur aset, profitabilitas, kebijakan dividen, pertumbuhan perusahaan dan ukuran perusahaan terhadap kebijakan hutang pada perusahaan perbankan yang listing di BEI tahun 2015-2018. Penelitian ini adalah penelitian deskriptif dengan pendekatan kuantitatif. Populasi yang digunakan dalam penelitian ini adalah seluruh perusahaan perbankan yang terdaftar pada BEI yang berjumlah 42 perusahaan. Sampel yang digunakan dalam penelitian ini yaitu dengan menggunakan Teknik Pengumpulan Data (Purposive Sampling) yang terdiri dari 9 perusahaan. Penelitian ini menggunakan metode analisis data yang digunakan adalah analisis regresi linier berganda dengan program SPSS Versi 22. Hasil penelitian menunjukkan bahwa struktur aset tidak berpengaruh terhadap kebijakan hutang dengan nilai signifikan 0,090, profitabilitas berpengaruh terhadap kebijakan hutang dengan nilai signifikan 0,004, kebijakan dividen berpengaruh terhadap kebijakan hutang dengan nilai signifikan 0,002, pertumbuhan perusahaan berpengaruh terhadap kebijakan hutang dengan nilai signifikan 0,000, ukuran perusahaan tidak berpengaruh terhadap kebijakan hutang dengan nilai signifikan 0,074. Hasil uji koefisien determinasi diperoleh R2 sebesar 0,792 atau 79,2%. Dapat diartikan bahwa 79,2% kebijakan hutang dalam model ini dipengaruhi oleh struktur aset, profitabilitas, kebijakan dividen, pertumbuhan perusahaan dan ukuran perusahaan. Sedangkan sisanya sebesar 20,8% dipengaruhi oleh faktor lain diluar model penelitian ini.
Analisis Performansi Protokol Routing Proaktif pada Jaringan Mobile Adhoc
Authors: Hidayah Rohmah Nur , Indrabayu Indrabayu , Areni Intan Sari 
Published: February 2020

Intelligent Transportation Systems (ITS) menawarkan paradigma pemodelan baru yang mendukung komunikasi antar kendaraan secara real time menggunakan routing protocol yang disebut Vehicular Ad Hoc Network (VANET). Pada dasarnya kinerja routing protocol dipengaruhi oleh arus dan aturan lalu lintas yang bersifat dinamis sehingga perubahan tersebut akan menyebabkan perubahan pada kinerja routing protocol juga. Untuk itu, penelitian ini mengusulkan rancangan mobilitas realistis berdasarkan data makroskopis dan mikroskopis jalan perkotaan. Rancangan mobilitas dibagi menjadi 2 skenario berdasarkan kepadatan kendaraan, yaitu 125 dan 200 node. Penelitian ini bersifat simulasi dan dibagi menjadi 2 tahap. Tahap pertama yaitu simulasi mobilitas yang menunjukkan pergerakan kendaraan serta aturan lalu lintas yang disesuaikan dengan kondisi realistis. Tahap kedua adalah simulasi jaringan yang bertujuan untuk mengevaluasi kinerja routing protocol DSDV dan OLSR terhadap rancangan model mobilitas. Untuk menguji kinerja kedua routing protocol, maka digunakan 3 metrik pengujian yaitu Packet Delivery Ratio (PDR), Overhead Ratio (OR) dan End to End Delay (E2ED). Hasil simulasi menunjukkan OLSR unggul pada metrik PDR dan OR, yaitu masing-masing 88.62% dan 57.11%. Sedangkan E2ED terbaik ditunjukkan oleh DSDV dengan nilai 0.523 detik. Kinerja terbaik kedua routing protocol ditunjukkan pada skenario 125 node. Hal ini menunjukkan kedua routing protocol belum mampu mengatasi kondisi lalu lintas perkotaan yang sangat padat.
Rancang Bangun Robot Pengangkut Sampah pada Kanal Sempit
Authors: Muhtar Muhtar , Syam Rafiuddin , Djafar Zulkifli 
Published: February 2020

Salah satu penyebab terjadinya banjir adalah faktor sampah yang banyak tersebar di kanal. Salah satu cara mengatasinya adalah dengan membuat robot pengangkut sampah pada kanal sempit. Adapun tujuan penelitian ini adalah merancang sebuah model robot pengangkut sampah pada kanal dan mampu membuat program arduino dalam mengopersikan robot tersebut. Bagian-bagian robot ini adalah rumah robot, rangka pengangkut sampah, pengangkut sampah, motor penggerak sistem, roda pengerak, arduino uno dan perangkatnya serta aki. Prinsip kerja robot ini adalah program memberi printah kerja pada sistem atau motor penggerak untuk menggerakkan rangka pengangkut sampah bergerak turun ke kanal untuk menemukan air. Di saat sensor air telah menyentuh air maka sensor akan mengirim ke program agar memberhentikan motor penggerak rangka pengangkut sampah. Bersamaan dengan itu, program memerintahkan/mengirim sinyal ke motor penggerak pengangkut sampah (jaring-jaring dan bilah pipa) agar berputar, sehingga bergerak menyaring sampah yang ada. Pada penelitian ini robot pengangkut mampu mengangkat sampah 5 kg sehingga diproleh torsi mesin 7,5 kg.cm dan Daya sebesar 117,75 Watt. Sedangkan menurut perhitungan mesin robot ini mampu mengangkat sampah sebesar 66,7 kg memiliki torsi sebesar 100 kg.cm dan daya sebesar 14401,7 watt.
Probiotics as prevention for gastro-intestinal disorders in pediatrics
Authors: Vandenplas Yvan 
Published: February 2020

This is a narrative review of largely randomized trials on the impacts of probiotics. It concludes that evidence for beneficial effects of selected probiotics in the prevention of gastrointestinal disorders is limited mainly to acute gastroenteritis, antibiotic-associated diarrhea, infantile colic and necrotizing enterocolitis. However, there is no broad consensus to recommend the use of probiotics in the prevention of these conditions, mainly because of the different designs used in different studies, resulting in limited evidence for specific strains, dosages and indications. More well-designed studies utilizing standardized methodologies are needed before recommendations can be proposed. At this stage, there is insufficient evidence to recommend the routine use of probiotics in infants and children for the prevention of gastro-intestinal disorders