bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cancerous pericarditis presenting as cardiac tamponade in a 68-year-old man with pancreatic adenocarcinoma: a case report
Authors: Kiryu Sachie , Ito Zensho , Ishikawa Masashi , Akasu Takafumi , Matsumoto Yoshihiro , Hirooka Shinichi , Saruta Masayuki , Koido Shigeo 
Published: November 2020

Abstract

Introduction
Pericardial effusion is a rare complication of pancreatic cancer. We report a case of cardiac tamponade secondary to pancreatic cancer.

Case presentation
A 68-year-old Japanese man was diagnosed as having pancreatic cancer during surgery and received chemotherapy for 28 months after the diagnosis. He was admitted to the emergency room with severe dyspnea. Echocardiography revealed pericardial effusion with severe hypofunction. Emergency pericardial drainage was performed to maintain hemodynamics, which resulted in the elimination of 450 mL of blood and the maintenance of circulatory dynamics. Cytological examination of the pericardial fluid revealed atypical cells and tumor cells suggesting adenocarcinoma.

Conclusions
To our knowledge, pancreatic cancer complicated with cancerous pericarditis has not been previously documented. This case highlights the extreme severity of pericardial effusion, a sign of progressive disease, secondary to pancreatic cancer. In the case of neoplastic pericardial effusion, an extremely poor prognosis must be considered.
Molecular and biological functions of resveratrol in psychiatric disorders: a review of recent evidence
Authors: Shayganfard Mehran 
Published: November 2020

Abstract
Mental disorders including depression, anxiety, schizophrenia, autism spectrum disorders, bipolar and etc. have a considerable proportion of global disorder burden. Many nutritional psychiatry investigations have been conducted to evaluate the relationship between several individual nutrients such as herbal compounds with mental health. Resveratrol, a famous polyphenol compound, is known as an antioxidant, anti-inflammatory, anti-apoptotic, and neuroprotective agent regulating the function of brain and improves the behavioral factors associated with learning, anxiety, depression, and memory. In addition, this natural compound can cross the blood–brain barrier representing neurological influences. The pharmacological interest of utilizing resveratrol in mental disorders is due to its anti-inflammatory and antioxidant features. The aim of this paper was to review the studies evaluated the potential effects of resveratrol on mental disorders.
Orbital stability of solitary waves for the generalized long-short wave resonance equations with a cubic-quintic strong nonlinear term
Authors: Zheng Xiaoxiao , Di Huafei , Peng Xiaoming 
Published: November 2020

Abstract
In this paper, we investigate the orbital stability of solitary waves for the following generalized long-short wave resonance equations of Hamiltonian form: $$ \textstyle\begin{cases} iu_{t}+u_{{xx}}=\alpha uv+\gamma \vert u \vert ^{2}u+\delta \vert u \vert ^{4}u, \\ v_{t}+\beta \vert u \vert ^{2}_{x}=0. \end{cases} $$

{

i

u
t

+

u

x
x

=
α
u
v
+
γ
|
u

|
2

u
+
δ
|
u

|
4

u
,

v
t

+
β
|
u

|
x
2

=
0
.

We first obtain explicit exact solitary waves for Eqs. (0.1). Second, by applying the extended version of the classical orbital stability theory presented by Grillakis et al., the approach proposed by Bona et al., and spectral analysis, we obtain general results to judge orbital stability of solitary waves. We finally discuss the explicit expression of $\det (d^{\prime \prime })$
det
(

d

″

)
in three cases and provide specific orbital stability results for solitary waves. Especially, we can get the results obtained by Guo and Chen with parameters $\alpha =1$
α
=
1
, $\beta =-1$
β
=
−
1
, and $\delta =0$
δ
=
0
. Moreover, we can obtain the orbital stability of solitary waves for the classical long-short wave equation with $\gamma =\delta =0$
γ
=
δ
=
0
and the orbital instability results for the nonlinear Schrödinger equation with $\beta =0$
β
=
0
.
Nonexistence of global solutions of fractional diffusion equation with time-space nonlocal source
Authors: Nabti Abderrazak , Alsaedi Ahmed , Kirane Mokhtar , Ahmad Bashir 
Published: November 2020

Abstract
We prove the nonexistence of solutions of the fractional diffusion equation with time-space nonlocal source
$$\begin{aligned} u_{t} + (-\Delta )^{\frac{\beta }{2}} u =\bigl(1+ \vert x \vert \bigr)^{ \gamma } \int _{0}^{t} (t-s)^{\alpha -1} \vert u \vert ^{p} \bigl\Vert \nu ^{ \frac{1}{q}}(x) u \bigr\Vert _{q}^{r} \,ds \end{aligned}$$

u
t

+

(
−
Δ
)

β
2

u
=

(
1
+
|
x
|
)

γ

∫
0
t

(
t
−
s
)

α
−
1

|
u

|
p

∥

ν

1
q

(
x
)
u
∥

q
r

d
s
for $(x,t) \in \mathbb{R}^{N}\times (0,\infty )$
(
x
,
t
)
∈

R
N

×
(
0
,
∞
)
with initial data $u(x,0)=u_{0}(x) \in L^{1}_{\mathrm{loc}}(\mathbb{R}^{N})$
u
(
x
,
0
)
=

u
0

(
x
)
∈

L
loc
1

(

R
N

)
, where $p,q,r>1$
p
,
q
,
r
>
1
, $q(p+r)>q+r$
q
(
p
+
r
)
>
q
+
r
, $0<\gamma \leq 2 $
0
<
γ
≤
2
, $0<\alpha <1$
0
<
α
<
1
, $0<\beta \leq 2$
0
<
β
≤
2
, $(-\Delta )^{\frac{\beta }{2}}$

(
−
Δ
)

β
2

stands for the fractional Laplacian operator of order β, the weight function $\nu (x)$
ν
(
x
)
is positive and singular at the origin, and $\Vert \cdot \Vert _{q}$

∥
⋅
∥

q

is the norm of $L^{q}$

L
q

space.
Vieta–Lucas polynomials for solving a fractional-order mathematical physics model
Authors: Agarwal P. , El-Sayed A. A. 
Published: November 2020

AbstractIn this article, a fractional-order mathematical physics model, advection–dispersion equation (FADE), will be solved numerically through a new approximative technique. Shifted Vieta–Lucas orthogonal polynomials will be considered as the main base for the desired numerical solution. These polynomials are used for transforming the FADE into an ordinary differential equations system (ODES). The nonstandard finite difference method coincidence with the spectral collocation method will be used for converting the ODES into an equivalence system of algebraic equations that can be solved numerically. The Caputo fractional derivative will be used. Moreover, the error analysis and the upper bound of the derived formula error will be investigated. Lastly, the accuracy and efficiency of the proposed method will be demonstrated through some numerical applications.
Different dimensional fractional-order discrete chaotic systems based on the Caputo h-difference discrete operator: dynamics, control, and synchronization
Authors: Talbi Ibtissem , Ouannas Adel , Khennaoui Amina-Aicha , Berkane Abdelhak , Batiha Iqbal M. , Grassi Giuseppe , Pham Viet-Thanh 
Published: November 2020

AbstractThe paper investigates control and synchronization of fractional-order maps described by the Caputoh-difference operator. At first, two new fractional maps are introduced, i.e., the Two-Dimensional Fractional-order Lorenz Discrete System (2D-FoLDS) and Three-Dimensional Fractional-order Wang Discrete System (3D-FoWDS). Then, some novel theorems based on the Lyapunov approach are proved, with the aim of controlling and synchronizing the map dynamics. In particular, a new hybrid scheme is proposed, which enables synchronization to be achieved between a master system based on a 2D-FoLDS and a slave system based on a 3D-FoWDS. Simulation results are reported to highlight the effectiveness of the conceived approach.
Novel hyperbolic and exponential ansatz methods to the fractional fifth-order Korteweg–de Vries equations
Authors: Park Choonkil , Nuruddeen R. I. , Ali Khalid K. , Muhammad Lawal , Osman M. S. , Baleanu Dumitru 
Published: November 2020

AbstractThis paper aims to investigate the class of fifth-order Korteweg–de Vries equations by devising suitable novel hyperbolic and exponential ansatze. The class under consideration is endowed with a time-fractional order derivative defined in the conformable fractional derivative sense. We realize various solitons and solutions of these equations. The fractional behavior of the solutions is studied comprehensively by using 2D and 3D graphs. The results demonstrate that the methods mentioned here are more effective in solving problems in mathematical physics and other branches of science.
Ameliorative effects of ark clams (Scapharca subcrenata and Tegillarca granosa) on endothelial dysfunction induced by a high-fat diet
Authors: Chanmuang Saoraya , Meemalai Orawan , Promyo Kitipong , Park Kyung-Hee , Pongworn Suthipong , Gong Dal-Seong , Oak Min-Ho , Cho Jeong-Yong , Kang Seong-Gook , Ham Kyung-Sik 
Published: November 2020

AbstractEndothelial dysfunction is directly involved in consequence of various metabolic syndromes such as diabetes and hypertension. In this study, we investigated the preventive effects of two ark clams [ark shell (AS,Scapharca subcrenata) and granular ark (GA,Tegillarca granosa)] on endothelial dysfunction induced by a high-fat diet. Wistar rats were divided into four groups as follows: control (normal diet), HF (high-fat diet), AS (high-fat diet + 5% AS powder), and GA (high-fat diet + 5% GA powder) for 12 weeks. AS and GA diets enhanced vascular reactivity of the rat thoracic aorta and significantly increased expression levels of vascular relaxation-related proteins (p-Akt-ser473 and p-eNOS-ser1177). Ark clam supplement reduced endothelin-1 expression level, as compared to the HF group. Additionally, AS and GA showed a trend of improving insulin sensitivity compared to HF. Our results suggest that AS and GA enhance vascular reactivity and ameliorated endothelial dysfunction induced by a high-fat diet.
Investigating the roles of age, sex, depression, and anxiety for valence and arousal ratings of words: a population-based study
Authors: Teismann Henning , Kissler Johanna , Berger Klaus 
Published: November 2020

AbstractBackgroundThe perception of the affective quality of stimuli with regard to valence and arousal has mostly been studied in laboratory experiments. Population-based research may complement such studies by accessing larger, older, better balanced, and more heterogeneous samples. Several characteristics, among them age, sex, depression, or anxiety, were found to be associated with affective quality perception. Here, we intended to transfer valence and arousal rating methods from experimental to population-based research. Our aim was to assess the feasibility of obtaining and determining the structure of valence and arousal ratings in the setting of the large observational BiDirect Study. Moreover, we explored the roles of age, sex, depression, and anxiety for valence and arousal ratings of words.Methods704 participants provided valence and arousal ratings for 12 written nouns pre-categorized as unpleasant, neutral, or pleasant. Predictors of valence and arousal ratings (i.e. age, sex, depression, and anxiety) were analyzed for six outcomes that emerge by combining two affective dimensions with three words categories. Data were modeled with multiple linear regression. Relative predictor importance was quantified by model-explained variance decomposition.ResultsOverall, average population-based ratings replicated those found in laboratory settings. The model did not reach statistical significance in the valence dimension. In the arousal dimension, the model explained 5.4% (unpleasant), 4.6% (neutral), and 3.5% (pleasant) of the variance. (Trend) effects of sex on arousal ratings were found in all word categories (unpleasant: increased arousal in women; neutral, pleasant: decreased arousal in women). Effects of age and anxiety (increased arousal) were restricted to the neutral words.ConclusionsWe report results of valence and arousal ratings of words in the setting of a large, observational, population-based study. Method transfer yielded acceptable data quality. The analyses demonstrated small effects of the selected predictors in the arousal dimension.
The Dark Triad of personality and attitudes toward cognitive enhancement
Authors: Mayor Eric , Daehne Maxime , Bianchi Renzo 
Published: November 2020

Abstract

Background
Cognitive enhancement (CE) refers to the voluntary improvement of human cognitive capabilities. Few studies have examined the general attitude of the public towards CE. Such studies have suggested that the use of CE is considered largely unacceptable by the public. In parallel, past research indicates that individuals scoring high on the Dark Triad of personality (Machiavellianism, narcissism, and psychopathy) and competitiveness have atypical views of ethical questions. In this study, we examined (a) whether attitudes towards CE are associated with individual differences in the Dark Triad of personality as well as in trait and contextual competitiveness and (b) whether the Dark Triad moderates the effect of trait and contextual competitiveness on attitudes towards CE.

Method
US employees (N = 326) were recruited using Mechanical Turk. Participants completed a web survey. Data were analyzed by means of (robust) hierarchical regression and (robust) ANCOVAs.

Results
The Dark Triad of personality and one of its subscales, Machiavellianism, predicted positive attitudes towards CE. Neither trait competitiveness nor contextual competitiveness were linked to general attitudes towards CE, but the DT was a positive moderator of the association between contextual competitiveness and positive attitudes.

Conclusion
Our findings extend the incipient knowledge about the factors relating to favourable views of CE by highlighting the role of dark personality traits in shaping such views. Our study further shows contextual factors can play a differentiated role with respect to such attitudes depending upon dark personality traits. Implications for policy-making are discussed.
Reduction of pin tract infections during external fixation using cadexomer iodine
Authors: Jansen Mylène P. , van Egmond Nienke , Kester Esmee C. , Mastbergen Simon C. , Lafeber Floris P. J. G. , Custers Roel J. H. 
Published: November 2020

Abstract

Purpose
Knee joint distraction (KJD) is a joint-preserving treatment for younger osteoarthritis patients. KJD has shown positive results in regular care, but the external fixation frame often caused pin tract skin infections. Therefore, the use of cadexomer iodine was included in the wound care protocol. The goal of this cross-sectional study was to evaluate whether use of this ointment reduced the number of patients with infections during KJD treatment.

Methods
Patients treated with KJD in regular care were included if they gave consent for use of their data and completed treatment with the newest distraction device before 2020. All patients followed a wound care protocol, which since March 2019 included using cadexomer iodine ointment. The number of patients experiencing pin tract infections was compared between patients who did (March 2019–December 2019) and did not (November 2017–March 2019) use the ointment.

Results
Sixty-seven patients were included; 34 patients used cadexomer iodine and 33 patients did not. Patient who did not use cadexomer iodine experienced twice as many infections (64% vs 32%;p = 0.010). There was a significant difference in the number of patients with serious infections, requiring more antibiotics than the standard 7-day oral antibiotics (30% without vs 6% with cadexomer iodine; p = 0.009).

Conclusions
The use of cadexomer iodine ointment during KJD results in a significant reduction of the number of patients experiencing pin tract infections during treatment. Use of this ointment should be considered standard protocol during KJD treatment and could be of value in general external fixator usage as well.
Pilot randomised clinical trial of an eHealth, self-management support intervention (iVERVE) for stroke: feasibility assessment in survivors 12–24 months post-event
Authors:   on behalf of the ReCAPS investigators, Cadilhac Dominique A. , Andrew Nadine E. , Busingye Doreen , Cameron Jan , Thrift Amanda G. , Purvis Tara , Li Jonathan C. , Kneebone Ian , Thijs Vincent , Hackett Maree L. , Lannin Natasha A. , Kilkenny Monique F. 
Published: November 2020

Abstract

Background
Electronic communication is used in various populations to achieve health goals, but evidence in stroke is lacking. We pilot tested the feasibility and potential effectiveness of a novel personalised electronic self-management intervention to support person-centred goal attainment and secondary prevention after stroke.

Methods
A phase I, prospective, randomised controlled pilot trial (1:1 allocation) with assessor blinding, intention-to-treat analysis, and a process evaluation. Community-based survivors of stroke were recruited from participants in the Australian Stroke Clinical Registry (AuSCR) who had indicated their willingness to be contacted for research studies. Inclusion criteria include 1–2 years following hospital admission for stroke and living within 50 km of Monash University (Melbourne). Person-centred goals were set with facilitation by a clinician using a standardised template. The intervention group received electronic support messages aligned to their goals over 4 weeks. The control group received only 2–3 electronic administrative messages. Primary outcomes were study retention, goal attainment (assessed using Goal Attainment Scaling method) and satisfaction. Secondary outcomes were self-management (Health Education Impact Questionnaire: 8 domains), quality of life, mood and acceptability.

Results
Of 340 invitations sent from AuSCR, 73 responded, 68 were eligible and 57 (84%) completed the baseline assessment. At the goal-setting stage, 54/68 (79%) were randomised (median 16 months after stroke): 25 to intervention (median age 69 years; 40% female) and 29 to control (median age 68 years; 38% female). Forty-five (83%) participants completed the outcome follow-up assessment. At follow-up, goal attainment (mean GAS-T score ≥ 50) in the intervention group was achieved for goals related to function, participation and environment (control: environment only). Most intervention participants provided positive feedback and reported that the iVERVE messages were easy to understand (92%) and assisted them in achieving their goals (77%). We found preliminary evidence of non-significant improvements between the groups for most self-management domains (e.g. social integration and support: β coefficient 0.34; 95% CI − 0.14 to 0.83) and several quality-of-life domains in favour of the intervention group.

Conclusion
These findings support the need for further randomised effectiveness trials of the iVERVE program to be tested in people with new stroke.

Trial registration
ANZCTR, ACTRN12618001519246. Registered on 11 September 2018—retrospectively registered.
Rapid response of Nelson’s syndrome to pasireotide in radiotherapy-naive patient
Authors: He Xin , Spencer-Segal Joanna L. 
Published: November 2020

Abstract

Background
Nelson’s syndrome is a well-described complication following bilateral adrenalectomy for management of Cushing’s disease. There is no consensus on optimal management of Nelson’s syndrome, characterized by the triad of pituitary corticotroph adenoma growth, elevated serum adrenocorticotropic hormone, and skin hyperpigmentation. Medical therapy with a variety of drug classes have been studied. One potentially promising drug already approved for Cushing’s disease is pasireotide, a somatostatin analog with affinity for multiple somatostatin receptors, including subtype 5, the most highly expressed receptor on corticotroph tumors.

Case presentation
A 24-year-old female was diagnosed with Cushing’s disease with initial ACTH levels around 700–800 pg/mL. She underwent transsphenoidal surgery without remission, followed by bilateral adrenalectomy. Over the subsequent 3 years, the patient developed skin hyperpigmentation, recurrent elevations of ACTH, and tumor recurrence requiring two additional transsphenoidal surgeries. After her third transsphenoidal resection, ACTH normalized, no residual tumor was seen on radiology, and the patient’s skin hyperpigmentation improved. She then had an uncomplicated full-term pregnancy, during which ACTH levels remained within normal limits. One month after delivery, ACTH levels began rising to a peak at 5,935 pg/mL. Imaging revealed two new bilateral pituitary adenomas, measuring 14 mm on the left, and 7 mm on the right. She was then started on pasireotide. After two months of therapy, ACTH decreased to 609 pg/mL, and repeat pituitary MRI showed interval decrease in size of both pituitary adenomas to 13 mm on the left and 6 mm on the right.

Conclusion
We report the protracted course of a young female with several recurrences of Nelson’s syndrome following bilateral adrenalectomy and multiple transsphenoidal surgeries, who ultimately responded to pasireotide. Unique features of her case not described previously are the response to pasireotide in a radiotherapy-naive patient, as well as the rapid radiologic response to therapy. Her history illustrates the unresolved challenges of Nelson’s syndrome and the continued need for additional studies to identify optimal management.
The relationship of personal budgets with independence, participation and quality of life; a secondary analysis of survey data using propensity score matching
Authors: Marangos Anna Maria , Iedema Jurjen , de Klerk Mirjam , Woittiez Isolde , Groenewegen Peter P. 
Published: November 2020

AbstractObjectivesPersonal budgets for social and health care have been introduced in many European countries over recent decades. The assumption is that people with a personal budget are able to purchase care that matches their needs more closely and therefore experience greater independence and improved well-being. The question is whether this assumption is true. Little research has been carried out on this and the research that has been carried out is inconclusive and hampered by methodological limitations.MethodsWe performed a secondary analysis of data collected in a survey among persons who had submitted an application for social support. Propensity score matching was used to investigate whether people with a personal budget experience better independence, participation in society and quality of life than comparable people using conventionally organised help.ResultsAfter matching, no significant effects of the personal budget were initially found. A sensitivity analysis that excluded the variable sense of mastery from the calculation of the propensity scores, showed a significantly greater independence for those using a personal budget.ConclusionThere may be several reasons for this lack of effect. First, perhaps there are no effects. It is also possible that effects can only be found in specific situations and/or specific groups.