bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eight-year Retrospective Analysis of Malaria Trends in Gedeo Zone, South Ethiopia (2012-2019)
Authors: Molla Eshetu , Behaksra Sinknesh Wolde , Tadesse Fitsum G , Dugassa Sisay , Gadisa Endalamaw , Mamo Hassen 
Published: August 2020

Abstract
Background: Informed decision making is underlined by all level of the tiers in the health system. Poor data record system coupled with under- (over)-reporting of malaria cases affects the country’s elimination activities. Thus, malaria data at health facilities and health offices are important particularly to monitor and evaluate malaria elimination progresses. This study was intended to assess overall reported malaria cases, spatiotemporal trends and factors associated in Gedeo zone, South Ethiopia, and compare malaria case reports by the health centers and health offices.Methods: Past eight years retrospective data stored in 17 health centers and 5 district health offices in Gedeo Zone were extracted. Malaria cases data at each health center with sociodemographic information, between 2012 and 2019, were included. Meteorological data were obtained from the national meteorology agency. The data were analyzed using Stata 13.Results: A total of 485,414 clinical suspects were examined for malaria during the previous 8 years at health centers. Of these suspects, 57,228 (11.79%) were confirmed malaria cases. We noted, an overall under reporting of malaria, 3,758 clinical suspects and 467 confirmed malaria cases were not captured at the health offices level. Based on the health centers records, Plasmodium falciparum (49.74%) was slightly higher (p = 0.795) than P. vivax (47.59%). The majority of cases were found in adults (≥15 years of age) that accounted for 11.47% of confirmed malaria cases (p < 0.0001). There was high spatiotemporal variation: highest cases record was during autumn (12.55%) (p < 0.0001) and, the highest (18,150, 13.17%)) and lowest (5,187 (10.44%)) malaria cases were reported from Dilla town and Yirgacheffe rural district, respectively (p = 0.0002). Monthly rainfall and minimum temperature exhibited strong positive associations with the number of confirmed malaria cases.Conclusion: A notable decline in malaria cases was observed over the eight-year period. Both P. falciparum and P. vivax co-exist; hence, control measures should continue targeting both species. The high malaria burden in urban (Dilla town) and suburban (Dilla zuria district) settings and autumn season need spatiotemporal consideration by the elimination program.
The Enhanced Pyrocatalysis of the Pyroelectric BiFeO3/g-C3N4 Heterostructure for Dye Decomposition Driven by Cold-hot Temperature Alternation
Authors: Chen Mingzi , Jia Yanmin , Li Huamei , Wu Zheng 
Published: August 2020

Abstract
The BiFeO3/g-C3N4 heterostructure, which is fabricated via a simple mixing-calcining method, benefits the significant enhancement of the pyrocatalytic performance. With the growth of the g-C3N4 content in the heterostructure pyrocatalysts from 0 to 25 %, the decomposition ratio of Rhodamine B (RhB) dye after 18 cold-hot temperature fluctuation (25 oC - 65 oC) cycles increases at first and then decreases, reaching a maximum value of ~ 94.2 % at 10% while that of the pure BiFeO 3 is ~ 67.7 %. The enhanced dye decomposition may be due to the fabrication of the heterostructure which strengthens the separation of the positive and negative carriers and further accelerates their migration. The intermediate products in the pyrocatalytic reaction also have been detected and confirmed, which proves the key role of the pyroelectric effect in realizing the dye decomposition using BiFeO3/g-C3N4 heterostructure catalyst. The pyroelectric BiFeO3/g-C3N4 heterostructure shows the potential application in pyrocatalytically degrading dye wastewater.
Alterations in Gut Vitamins and Amino Acids Metabolism are Associated with Symptoms and Neurodevelopment of Children with Autism Spectrum Disorders
Authors: Zhu Jiang , Hua Xueying , Yang Ting , Guo Min , Li Qiu , Xiao Lu , Li Ling , Chen Jie , Li Tingyu 
Published: August 2020

Abstract
Background Accumulated evidence have supported metabolic disturbance may be associated with the pathogenesis of autism spectrum disorders (ASD). Despite abnormalities of some shared metabolic pathways, specific differential compounds are inconsistent in studies, which made a challenge to elucidate the role of metabolism in the mechanism of ASD. Besides, few researches have assessed the correlation between gut metabolites with symptoms of ASD. Objectives The present study aimed to evaluate the gut metabolomic profiles of children with ASD and to analyze potential interaction between gut metabolites with symptoms and neurodevelopment of ASD children. Methods In this cross-sectional case-control study, 120 aged 2–6 years ASD children and 60 sex and age matched typically developing (TD) children were included. Autistic symptoms were assessed with the Autism Behavior Checklist (ABC), Childhood Autism Rating Scale (CARS), and the Social Responsiveness Scale (SRS). Neurodevelopment was assessed with the Gesell Developmental Scale (GDS). Fecal samples were analyzed by untargeted liquid chromatography-mass spectrometry (LC-MS) methods, then systematic bioinformatic analyses were performed to characterize the gut metabolomic profiles of ASD and TD children. The correlations between metabolites and clinical assessment scores were assessed using Spearman correlation. Results ASD children exhibit gut metabolism perturbation compared with TD children. A total of 96 differential metabolites between the ASD and TD groups were identified, with 35 increased and 61 decreased in ASD group. The metabolic disturbance of ASD involved in multiple vitamins and amino acids metabolism pathways, with the strongest enrichment identified for tryptophan metabolism, retinol metabolism, cysteine and methionine metabolism, and vitamin digestion and absorption. The imbalanced gut metabolites are significantly correlated to symptoms and neurodevelopment of ASD children. Limitations This cross-sectional study revealed a correlation, but do not allow to prove causation of symptoms and gut metabolites outcome. The disease specificity of the metabolomic disturbance need to be evaluated in future studies.Conclusions ASD children have altered gut metabolite profiles compared with TD children, which mainly involved in multiple vitamins and amino acids metabolism pathways. Notably, vitamins metabolism abnormalities may play roles in the disturbance of amino acids metabolism. Imbalanced gut metabolites are related to symptoms and neurodevelopment of ASD children. Our findings provided an improved understanding of perturbations of metabolome networks in ASD.
Establishment of a Rapid, Lesion-Controllable Retinal Degeneration Model in Monkey for Preclinical Stem Cell Therapy
Authors: Gao Guanjie , He Liwen , Liu Shengxu , Zheng Dandan , Song Xiaojing , Zhang Wenxin , Yu Minzhong , Luo Guangwei , Zhong Xiufeng 
Published: August 2020

Abstract
Background: Retinal degenerative disorders (RDs) are the main cause of blindness without curable treatment. Our previous studies have demonstrated that human induced pluripotent stem cells can differentiate into retinal organoids with all subtypes of retina, which provides huge promises for treating these diseases. Before it can be turned into reality, RD animal models are required to evaluate the safety and efficacy of stem cell therapy, and to develop the surgical tools and procedures for cell transplantation in patients. This study is to develop a monkey model of RD with controllable of lesion sites which can be rapidly prepared, for the studies of preclinical stem cell therapy among other applications.Methods: Sodium nitroprusside (SNP) in three doses was delivered into the monkey eye by subretinal injection (SI) and normal saline was applied as control. Structural and functional changes of the retinas were evaluated via multimodal imaging techniques and multifocal electroretinography (mfERG) before and after the treatment. Histological examination was performed to identify the target layer of the affected retina. The health status of monkeys was monitored during the experiment. Results: Well defined lesion with various degree of retinal degeneration was established at the posterior pole of retina as early as 7 days after SNP SI. The damage effect of SNP was dose-dependent. 0.05 mM SNP caused invisible structural changes in retina, similar to the control. 0.1 mM SNP led to the loss of outer retinal layer, including OPL, ONL and RPE, while 0.2 mM SNP impacted the entire layer of retina and choroid. MfERG showed reduced amplitude in the damaged region. The structural and functional damages were not recovered after 7-month follow-up. Conclusion: A simple, rapidly induced, lesion site-controllable, retinal degeneration model in monkey was established by the subretinal injection of 0.1 mM SNP. This monkey model closely mimics the histological changes of RDs, and provides a valuable platform for preclinical assessment of stem cell therapy.
Jet-A-Way Inc.: Winning Despite the Odds
Authors: Betters-Reed Bonita L. , Moore Lynda L. 
Published: August 2020

“This is the hand that God dealt me and I am going to play it” Darlene Jeter, 1991. Darlene Jeter, co-founder of Jet-A-Way Inc., a recycling and waste disposal company, became CEO in 1991 upon the death of her husband, Eddie Jeter. Despite a recent loss of almost 50% in their company’s revenue, Jeter decided to keep the cards she was dealt, playing for the longer run. Today, Jet-A-Way is a seventeen million dollar company. A certified minority-owned business near downtown Boston, Jet-A-Way became known as a family-run company that gives back to the community in jobs and in service. Now Jeter and her team face new challenges—a volatile industry, production issues and the succession of her son Jesse Jeter as CEO while Darlene shifts her role to “Madame Chair.”
Mental Health Professional Consultations and the Prevalence of Mood and Anxiety Disorders Among Immigrants: Multilevel Analysis of the Canadian Community Health Survey
Authors: Nwoke Chinenye Nmanma , Okpalauwaekwe Udoka , Bwala Hauwa 
Published: August 2020

Background
There is a significant body of evidence on the link between migration and mental health stressors. However, there has been very little research on the use of mental health services by immigrants in Canada. The prevalence of mental health professional consultations among immigrants, as well as its correlations, are not well understood and remain largely unknown.

Objective
This study aims to examine how specialist mental health visits (to a psychiatrist) differ from general mental health visits (to a family doctor or general practitioner) from immigrants, when compared to visits from those born in Canada, in a nationally representative sample of Canadian adults. This study also examines which group—immigrant or Canadian-born—suffers more from depression or anxiety, 2 of the more common mental health conditions.

Methods
We used data from the Canadian Community Health Survey (CCHS) between the years 2015 and 2016. The outcome variables included consultation with any mental health professional, consultation with a specialist (psychiatrist), and the prevalence of mood and anxiety disorders. The independent variable was immigrant status. Other variables of interest were adjusted for in the analyses. Multilevel regression models were developed, and all analyses were performed with Stata IC statistical software (version 13.0, StataCorp).

Results
The prevalence of mood and anxiety disorders was significantly lower among immigrants compared with individuals born in Canada; the prevalence of mood disorders was 5.24% (389,164/7,422,773) for immigrants vs. 9.15% (2,001,829/21,885,625) for individuals born in Canada, and the prevalence of anxiety disorders was 4.47% (330,937/7,410,437) for immigrants vs. 9.51% (2,083,155/21,898,839) for individuals born in Canada. It is expected that individuals with a lower prevalence of mood or anxiety disorders would use mental health services less frequently. However, results show that immigrants, while less likely to consult with any mental health professional (OR=0.80, 95% CI 0.72-0.88, P<.001), were more likely to consult with a psychiatrist (OR=1.24, 95% CI 1.04-1.48, P=.02) for their mental health visits when compared to individuals born in Canada.

Conclusions
The results of this study reveal an unusual discord between the likelihood of mental health professional consultations with any mental health professional and mental health visits with psychiatrists among immigrants compared to nonimmigrants in Canada. Mental health initiatives need to be cognizant of the differences in the associated characteristics of consultations for immigrants to better tailor mental health services to be responsive to the unique needs of immigrant populations in Canada.
Pembatalan Perjanjian Pengikatan Jual Beli (PPJB) Kondominium Akibat Wanprestasi
Authors: Abel Agustian  
Published: August 2020

ABSTRAK
Indonesia adalah Negara berkembang.Seiring dengan perkembangannya yang pesat, berkembang juga hal-hal di bidang property, misalnya peminat dalam jual beli kondominium atau yang lebih dikenal dengan istilah apartment.Namun seiring dengan banyaknya peminat dalam hal jual beli kondominium tersebut tak jarang juga menimbulkan berbagai problematika.Tujuan dari penelitian ini adalah untuk mengetahui hal-hal yang dapat menyebabkan batalnya akta Perjanjian Pengikatan Jual Beli (PPJB) atas Kondominium serta mengetahui akibat hukum apabila dilakukan pembatalan perjanjian.Kelalaian dapat merugikan salah satu pihak, akibatnya hal ini dapat menyebabkan dibatalkannya suatu perjanjian. Sedangkan akibat batalnya Perjanjian Pengikatan Jual Beli (PPJB) atas Kondominium yang dibuat dihadapan notaris karena wanprestasi dapat berupa denda, sanksi, pembatalanterhadap akta yang dibuat dihadapan notaris, dan pembayaran biaya perkara akibat pembatalan Perjanjian Pengikatan Jual Beli (PPJB). Dalam penelitian ini, digunakan metode penelitian yuridis normatif, dalam melakukan pengkajian terhadap Undang-Undang. Adapun hasil dari penelitian yang dapat diberikan dalam penelitian ini adalah penyebab batalnya Perjanjian Pengikatan Jual Beli (PPJB) atas Kondominium dapat dikarenakan oleh adanya pihak yang tidak memberikan prestasi yang telah disepakati, sehingga menyebabkan kerugian disalah satu pihak.

Kata Kunci : Pembatalan PPJB, Wanprestasi
Analisis Yuridis Kepemilikan Hak Atas Tanah Terdaftar Atas Nama Anak Yang Bersumber Dari Nominee Akta (Studi Putusan Nomor: 433K/PDT/2016)
Authors: Siregar Muhammad Takkas 
Published: August 2020

Nominee Arrangement drafted by a Notary has quite wide range of usage because it contains authority. Nominee is principally an agreement that is not assertively specifically regulated, but in practice, it is used as an agreement with name borrowing which existence frequently brings negative impacts and financial loss to all parties if its deed is proceeded.
The objective of this research was to analyze the legal regulations related to notarial deed drafting categorized into deed of nomination, the legal status of the land title registered with the name of a child mentioned in a nominee deed, and the Verdict of the Supreme Court Number 433K/Pdt/2016. Normative juridical research method is employed with descriptive analysis. The data are collected through library study. The research problems are about the land title ownership sourced from nominee or name borrowing. The legal regulations on notarial deeds that are categorized into deed of nomination causes many legal problems in practice; thus, the practice of nominee arrangement has to be made with a supporting agreement to build legal relationship among all parties, that the legal smuggling seems legitimate and has legal ground.
The results demonstrate that the usage of nominee concept in land ownership is aimed at protecting the confidentiality of the true owner’s name and identity from public and government. The legal status of deed of nomination is not specifically regulated, but the Law on Capital Market and Law on Limited Liability Companies stipulate regulations on nominee. The analysis result of this verdict is that the judges should be more conscientious in analyzing, deciding, and pronouncing the verdict by involving competent experts; it can be made guidance to make decision. The ruling issued by a court reflects a just legal protection for all disputed parties in Indonesia.
Jual Beli Di Bawah Tangan Terhadap Lahan Tempat Tinggal Transmigran Di Nagari Ranah Palabi Kecamatan Timpeh Kabupaten Dharmasraya Provinsi Sumatera Barat (Studi Pada Kantor Pertanahan Kabupaten Dharmasraya Provinsi Sumatera Barat)
Authors: Putra Randa Iolanda 
Published: August 2020

ABSTRACT
The registration of land rights concerning title status, right subject, and right object is intended to guarantee legal certainty, legal protection, utility. According to UUPA, PP on Land Registration, and its derivation, it is one of the activities of safeguarding the land. The change in physical data and/or juridical data include the coverage of land registration data by transaction which can be proved with PPAT certificate. In reality, in Nagari Ranah Palabi, the transaction is done underhendedly on land title of the transmigrant settlement. The research problem is how about the cause, legal standing, and registration of the transfer of underhanded land transaction on the land right of transmigrant settlement. The research theories are the theory of legal certainty, theory of legal protection, and theory of utility. The research used juridical empirical and descriptive analytic method by analyzing primary data obtained directly from the people in the field. It wa done in Nagari Ranah Palabi, Timpeh Sub-district, Dharmasraya Regency, West Sumatera Province.
The result of the reseacrh shows that underhanded transaction of the land of transmigrant settlement includes inexpensive cost, quick process, and easy to do. Legal standing of the transactiondoes not meet material requiment since it is not a certificate made before a PPAT even thougt it is allowed materially. Consequently, it cannot be registered in the Land Office and filing the claim to Court cannot do the proceeding because there is no dispute in it. Therefore, the request for the right for the land cannot be accepted by the Court.
It is recommended thet legal counseling about legal consequense of underhanded transaction of the land for residence be provided. Accurate regulation for the people on land right for residence concerning formal preprequisite should be made – certificate made before a PPAT for registering land title transfer. Concerning the absence of the seller or ‘afwezigheid’ the buyer has the right to lodge a request the land right in the transmigrant land.
Keywords : Land Transaction;Land for Residence;Transmigrant.
The Influence of Effectiveness Managerial, Task Commitment and Work Ethic for Employee Performance Regional Water Company (Pdam) Tirta Bhagasasi Bekasi
Authors: . Kusnadi 
Published: August 2020

The purpose of this study was to test the effect of managerial effectiveness to employee performance, task commitment to employee performance, work ethic on the performance of employees, managerial effectiveness to task commitment, managerial effectiveness to the work ethic and the work ethic of the commitment of the employee's duties Regional Water Company (PDAM) Tirta Bhagasasi Bekasi.
This research was conducted using the method suryey with path analysis in hypothesis testing. In this study, employees were selected as sample there are 96 employees who selected a random sample by strata or stratified random sampling from a total population of 127 respondents. Took this instrument before being used for the data to test the validity and reliability.
The results of this study are as follows: There is a direct positive influence on employee performance managerial effectiveness. There is a direct positive influence on employee performance task commitment. There is a direct positive influence on employee performance work ethic. There is a direct positive influence on the effectiveness of managerial task commitment. There is a direct positive effect managerial effectiveness to the work ethic. There is a direct positive effect on the work ethic of commitment to the task.
Effect of dietary sodium acetate on skin mucus immune parameters and expression of gene related to growth, immunity and antioxidant system in common carp (Cyprinus carpio) intestine
Authors: Safari Roghieh , Hoseinifar Seyed Hossein , Dadar Maryam , Nejadmoghaddam Shabnam , Van Doan Hien 
Published: August 2020

Abstract
The present study investigated the possible effects of including salt of short chain fatty acid, sodium acetate (SA), on skin mucus immune parameters and immune, antioxidant and growth-related genes expression in common carp. There is a little data available about the effective role of SA on immune, antioxidant and growth related genes expression as well as skin mucus immune parameters. The aim of this study was to analysis the effect of SA intake on these factors using common carp (Cyprinus carpio) as model organism. Two hundred and forty healthy common carp (mean weight = 15 ± 0.9 g) supplied and randomly stocked into 12 fiberglass tanks 200 L (20 fish per tank) assigned to four treatments and triplicates. The study was performed in a completely randomized design. The treatments were feeding carps with experimental diets containing different levels (0.0 [control], 0.5, 1 and 2%) of SA. The skin mucus total immunoglobulin and total protein levels in fish fed 2% SA showed significant increase compared to the control group (P < 0.05). Results showed a significant increase in the GH gene expression in 1 and 2% SA treatments (P < 0.05). The carps were fed with diet content 2% SA showed significantly increase in IGF-1 expression (P < 0.05). The expression of GSTa, and GPX (antioxidant genes) revealed a significant increase in the GSTa (fish fed SA at 1% and 2% levels) and GPX gene expression with fish fed 2% SA (P < 0.05). Supplementation of fish diet with SA induce slight elevation in the intestine of all immune-related genes (TNF-α, IL-1β, IL8 and Lyz) compared to the control group (P > 0.05). However, Lyz gene significantly up-regulated in 1 or 2% SA treatments. These results confirmed beneficial effects of SA as a feed additive in common carp culture.
Encouraging an appropriate representation simplifies training of neural networks
Authors: Buza Krisztian 
Published: August 2020

Abstract
A common assumption about neural networks is that they can learn an appropriate internal representation on their own, see e.g. end-to-end learning. In this work we challenge this assumption. We consider two simple tasks and show that the state-of-the-art training algorithm fails, although the model itself is able to represent an appropriate solution. We will demonstrate that encouraging an appropriate internal representation allows the same model to solve these tasks. While we do not claim that it is impossible to solve these tasks by other means (such as neural networks with more layers), our results illustrate that integration of domain knowledge in form of a desired internal representation may improve the generalization ability of neural networks.
𝒫-energy of graphs
Authors: Joshi Prajakta Bharat , Joseph Mayamma 
Published: August 2020

Abstract
Given a graph G = (V, E), with respect to a vertex partition 𝒫 we associate a matrix called 𝒫-matrix and define the 𝒫-energy, E𝒫 (G) as the sum of 𝒫-eigenvalues of 𝒫-matrix of G. Apart from studying some properties of 𝒫-matrix, its eigenvalues and obtaining bounds of 𝒫-energy, we explore the robust(shear) 𝒫-energy which is the maximum(minimum) value of 𝒫-energy for some families of graphs. Further, we derive explicit formulas for E𝒫 (G) of few classes of graphs with different vertex partitions.