bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical constituents from fruits of Macaranga denticulata (Euphorbiaceae) (Part 2)
Authors: Vu Le Tran Nguyen , Ngan Truong Bich , Phuong Le Thi , Huong Doan Thi Mai , Litaudon Marc , Van Hung Nguyen , Thach Tran Dang , Van Cuong Pham 
Published: February 2020

AbstractMacaranga denticulata is a 15‐18 m tall plant with rounded edges and long, rounded bark, 5 mm wide black covered with glands. In traditional medicine, this plant was used to treat fulminant hepatitis, dysentery, and urinary retention. In previous studies, we reported 13 isolated compounds from the fruits of Macaranga denticulata. In this study, we describe the isolation and structural characterizations of seven compounds: 5‐((E)‐3,5‐dihydroxystyryl)‐3‐((E)‐3,7‐dimethylocta‐2,6‐dien‐1‐yl)benzen‐1,2‐diol (1), poilaneic acid (2), stigmast‐4‐en‐6β‐ol‐3‐one (3), taraxerol (4), rel‐5‐(3S, 8S‐dihydroxy‐1R,5S‐dimethyl‐7‐oxa‐6‐oxobicyclo[3,2,1]‐oct‐8‐yl)3‐methyl, 2Z,4E‐pentadienoic acid (5), ellagic acid 3,3'‐dimethyl ether‐4‐O‐β‐D‐glucopyranoside (6), 3‐hydroxypropanoic acid (7). The structures of the isolated compounds were established on the basis of their spectral data, including mass and NMR spectrometry.
Synthesis and characterization of Fe3O4/GO nanocomposite for drug carrier
Authors: Hanh Nguyen Thi , Xuyen Nguyen Thi , Thuy Tran Thi Thanh 
Published: February 2020

AbstractA magnetite‐graphene oxide nanocomposite for biological applications was successfully synthesized. The nanocomposite composed of nanosized superparamagnetic iron oxide nanoparticles (SPIONs), graphene oxide (GO) and matodextrin as a biocompatible polymer matrix. Structural and physico‐chemical properties of the nanocomposite were analyzed by XRD, FT‐IR, TEM and vibrating sample magnetometer (VSM). TEM images showed that SPIONs had an average diameter size of about 10 nm and VSM results showed superparamagnetic behavior. SPIONs was well dispersed in the presence of GO and maltodextrin. Drug loading and drug release tests showed high loading efficiency of rutin onto SPIONs/GO and quite fast release of rutin in PBS solution at pH value of 7.4.
Flavonol glycosides from Phoebe poilanei Kosterm
Authors: Viet Thanh Nguyen Thi , Thu Hien Dinh Thi , Minh Tran Thi , Nhiem Nguyen Xuan , Yen Pham Hai , Van Kiem Phan 
Published: February 2020

AbstractSix flavonol glycosides, kaempferol 3‐O‐[β‐D‐xylopyranosyl‐(1 → 6)‐β‐D‐glucopyranoside] (1), kaempferol 3‐O‐β‐D‐glucopyranoside (2), kaempferol 3‐O‐[α‐L‐rhamnopyranosyl‐(1 → 2)‐β‐D‐glucopyranoside] (3), kaempferol 3‐O‐[α‐L‐rhamnopyranosyl‐(1 → 6)‐β‐D‐glucopyranoside] (4), kaempferol 3‐O‐[α‐L‐rhamnopyranosyl‐(1 → 6)‐β‐D‐galactopyranoside] (5), and rhamnocitrin 3‐O‐α‐L‐rhamnopyranosyl‐(1 → 6)‐[α‐L‐rhamnopyranosyl‐(1 → 2)]‐β‐D‐galactopyranoside (oxytroflavoside G) (6) were isolated from the leaves of Phoebe poilanei Kosterm. Their chemical structures were elucidated by analyses of their ESI‐MS, NMR spectral data, and comparison with those reported in the literature. This is the first report of 13C‐NMR data of compound 1.
An attempt to use pencil leads as cheap materials for electrochemical sensor
Authors: Dang Vu Hai , Anh Nguyen Hoang , Yen Pham Thi Hai , Giao Nguyen Quynh , Ha Vu Thi Thu 
Published: February 2020

AbstractDue to their electrochemical and economical characteristics, pencil leads can be used as electrodes for electrochemical analysis. These graphite‐based electrodes are recognized by their low‐cost and commercial availability. This paper presents the synthesis of gold nanodendrite network porous structure on pencil lead and its application in recording signals of Hg(II) in water environment. Influences of deposition time (tdep) used to fabricate Au nanodendrite structure on electrodes surface, sensor electrochemical behaviors and voltammetric signal of Hg(II) have been studied. The obtained results open a possibility to employ this simple, eco‐friendly material in developing electrochemical sensor, which can be implemented for heavy metal detection.
Insights into the adsorption of organic molecules on rutile TiO2 (1 1 0) surface: A theoretical study
Authors: Tri Nguyen Ngoc , Dai Ho Quoc , Trung Nguyen Tien 
Published: February 2020

AbstractWe investigated the adsorption of formic, acetic, benzoic acids, phenol, nitrobenzene molecules on rutile‐TiO2 (1 1 0) surface using the density functional theory (DFT) calculations. Details of the interaction between the investigated molecules and rutile‐TiO2 (1 1 0) surface were thoroughly considered by using the charge transfer and atoms in molecules analyses. The most stable configurations have been found upon adsorption of these molecules on TiO2 surface by employing the Perdew‐Burke‐Ernzerhof (PBE) functional and projector‐augmented wave method approach and utilizing the periodic slab model. The adsorption processes are determined to be strong chemisorptions, characterized by high adsorption energies in the range of ‐18.5 to ‐28.8 kcal.mol‐1. Stability of the adsorption configurations is significantly contributed by attractive Ti∙∙∙O electrostatic interaction and O‐H∙∙∙O strong hydrogen bond. The interactions between the adsorbed molecules on the rutile‐TiO2 (1 1 0) surface are stronger for the >COOH groups than for–OH or –NO2 groups. The results show that the TiO2‐rutile is regarded as a potential adsorption material and an efficient photocatalyst for removal of these organic compounds.
Influence of Darocur 1173 photoinitiator on the photocrosslinking and properties of UV‐cured coatings based on an epoxidiacrylate oligomer and hexanediol diacrylate monomer
Authors: Hien Le Xuan , Thanh Do Minh , Tai Nguyen Huu 
Published: February 2020

AbstractThe influence of Darocur 1173 (D.1173) photoinitiator content on the photocrosslinking of the coatings based on an epoxy diacrylate oligomer (EDA), hexanediol diacrylate monomer (HDDA) and properties of UV cured coatings have been studied. The fast conversion of acrylate groups and UV crosslinking of the coatings were shown by IR‐spectroscopy analysis and gel fraction determination, respectively. It was found that there was an optimal relationship between conversion of acrylate groups, as well as the hardening rate of the coatings and contents of D.1173, ranging from 0 to 2 % of total amount of EDA and HDDA, under UV exposure. The optimal content of D.1173 was determined to be 1 % and the UV curing of the coating having the weight ratio of the constituents EDA/HDDA/D.1173 = 50/50/1 occurred very fast, leading to formation of a high performance UV cured coating which can be used in different sectors of applications as decorative, protective coatings or adhesives.
Ionic liquids assisted desulfurization and denitrogenation of fuels
Authors: Zolotareva Darya , Zazybin Alexey , Rafikova Khadichakhan , Dembitsky Valery M. , Dauletbakov Anuar , Yu Valentina 
Published: February 2020

AbstractIn this article the regulations and policy about S‐ and N‐containing compounds in fuels, the general information about methods of desulfurization (DS) and denitrogenation (DN) and ionic liquids (ILs) assisted DS and DN are considered. We presented the most effective and novel methods of sulfur and nitrogen compounds removal using ILs from model and real fuels.
Inhibitory Selaginellins from Selaginella tamariscina against LPS‐induced NO production in RAW264.7 cells
Authors: Tuan Nguyen Dinh , Thuy Do Thi , Quan Pham Minh , Hung Nguyen Phi 
Published: February 2020

AbstractThree selaginellins have been isolated and structurally identified as selaginellin (1), selaginellin M (2), and selariscinin B (3) from Selaginella tamariscina, by interpretation of spectroscopic (1H, 13C NMR and MS) data and comparing with literatures. Compounds 1‐3 exhibited potential inhibition on lipopolysaccharide‐induced nitric oxide (NO) production in RAW 264.7 cells with IC50 values of 21.0 ± 1.2, 4.5 ± 0.6, and 18.1 ± 0.9 μM, respectively. Celastrol was used as positive control showing an IC50 value of 1.0 ± 0.1 μM. This obtained data reveals the potential of these selaginellin type compounds in the development of anti‐inflammatory agents from medicinal plants.
Formation of nanoemulsion from black pepper essential oil by high speed homogenization method
Authors: Hien Ly Thi Minh , Dao Dong Thi Anh 
Published: February 2020

AbstractAs many spices essential oil, black pepper (Piper nigrum) oil, which produced by steam distillation has shown the antimicrobial activity in many researches. However, essential oil was often hydrophobic and dispersed incompletely in food matrix. In our work, an oil‐in‐water nanoemulsion of black pepper oil was prepared by high speed homogenization method. In order to well disperse essential oil in water, the surfactant polyoxyethylene sorbitan monooleate (Tween 80) was utilized with the surfactant:oil ratios from 1:3 to 2:1. The other component of the nanoemulsion was soya oil, the high chain triglycerides in soya oil prevented the Oswald ripening of essential oil droplets by increasing their hydrophobicity. After changing the component concentration, the nanoemulsion was the most stable with 20 % oil phase, 6:4 pepper oil ‐ soya oil ratio and 1:1 surfactant oil ratio. At 9,000 rpm and 30 minutes stirring, the average droplet size was 61.9 nm with 0.462 PdI (polydispersity index). After 30‐day storage, the particle size increased to 87 nm at ambient temperature and 130 nm at 5°C.
Synthesis, characterization and luminescence properties of ZrBDC:Eu3+,Tb3+ nanoscaled metal organic frameworks
Authors: Giang Lam Thi Kieu , Agnieszka Opalińska , Marciniak Łukasz , Tien Dinh Manh , Linh Pham Hoai , Binh Pham Thanh , Vu Nguyen , Binh Nguyen Thanh , Minh Le Quoc 
Published: February 2020

AbstractZirconium nanoscaled metal–organic frameworks doped and co‐doped with Eu3+ and/or Tb3+ (ZrBDC:Eu3+,Tb3+) have been synthesized by hydrothermal method using 1,4‐dicarboxylic acid as linkers. The luminescence spectra obtained indicated that under 254 nm excitation, the as‐synthesized ZrBDC:Eu3+,Tb3+ and ZrO2:Eu3+,Tb3+ nanoparticles have multicolour visible emissions at 473, 591, 612 and 701 nm assigned to the 5D0 → 7F1, 5D0 → 7F2, 5D0 → 7F3 and 5D0 → 7F4 transition of Eu3+ ions and at 488, 582 and 621 nm assigned to 5D4 → 7F, 5D4 → 7F5; 5D4 → 7F4 and 5D4 → 7F3 transitions of Tb3+ ions, respectively. The X‐ray diffraction and field emission scanning electron microscopy results suggest that the ZrBDC:Eu3+,Tb3+ nanoscaled metal–organic frameworks can be used as precursors to design the tetragonal phase of ZrO2:Eu3+,Tb3+ nanoparticles with high purity and a narrow size distribution via heat treatment process. The as‐prepared ZrO2:Eu3+,Tb3+ nanoparticles have size of about 10‐15 nm with BET multipoint surface area of 162 m2/g.
Stability and semi‐conductive property of some derivatives of mono‐and di‐silole: A theoretical study
Authors: Van Trang Nguyen , Dung Tran Ngoc , Thoa Tran Thi , Thanh Dinh Thi Mai , Hue Nguyen Thi Minh 
Published: February 2020

AbstractForty – two derivatives of mono‐ and di‐ siloles have been studied by the density functional theory (DFT). The substituents consist of the electron donating groups (methyl, ethyl) and withdrawing groups (F, Cl, Br). The obtained calculations agree well with the experiment (the largest deviation of 1.59 % of the experimental value). Besides, the result also showed that the attachment of the substituents enhances the semi‐conductive properties of the derivatives. In addition, effects of the electron withdrawing groups on the stability and semi‐conductivity are better than these of the electron donating groups. Interestingly, the Br‐substituent occupies the most outstanding position.
Flavonol glycosides and dammarane saponin from Gouania leptostachya
Authors: Thuy Nguyen Thi Kim , Trang Do Thi , Trang Mai Thi Nhu , Bay Ninh Khac , Tai Bui Huu , Van Kiem Phan , Yen Pham Hai , Nhiem Nguyen Xuan 
Published: February 2020

AbstractUsing combined chromatographic methods, two flavonol glycosides and one dammarane‐type saponin were isolated from the methanol extract of the leaves of Gouania leptostachya. Their structures were elucidated to be quercetin 3‐O‐β‐D‐xylopyranosyl‐(1 → 2)‐α‐L‐rhamnopyranoside (1), quercetin 3‐O‐6‐E‐p‐coumaroyl‐β‐D‐glucopyranosyl‐(1 → 2)‐α‐L‐rhamnopyranoside (2) and joazeiroside A (3) by 1D‐, 2D‐NMR, and MS spectra and in comparison with those reported in the literature. These compounds have been reported from the Gouania genus for the first time.
Diagnostik und Therapie des Morbus Perthes
Authors: Strobl Walter Michael 
Published: February 2020

ZusammenfassungDie Behandlung des M. Perthes stellt aufgrund der ungeklärten Ätiologie sowie der unterschiedlichen Verlaufsformen und Behandlungskonzepte eine Herausforderung dar. Die Prognose ist abhängig von klinischen und radiologischen Parametern. Aktuelle Behandlungsansätze zielen in frühen Krankheitsstadien auf die Verbesserung der Durchblutung des Femurkopfes und später auf die Vergrößerung des Bewegungsumfangs sowie die Verminderung der vertikal einwirkenden Kräfte durch Teilentlastung und chirurgisch verbesserte Einstellung des Femurkopfes in der Gelenkpfanne ab. Da einerseits ein hoher Prozentsatz an Spontanremissionen ohne Deformitäten des Gelenks, andererseits ein hohes Risiko für eine schwere Koxarthrose mit der Notwendigkeit eines frühen Gelenkersatzes sowohl nach konservativen als auch nach operativen Verfahren zu beobachten sind, werden die Behandlungsmethoden kontrovers diskutiert.
Novel chloroquine loaded curcumin based anionic linear globular dendrimer G2: a metabolomics study on Plasmodium falciparum in vitro using 1H NMR spectroscopy
Authors: Elmi Taher , Shafiee Ardestani Mehdi , Hajialiani Fateme , Motevalian Manijeh , Mohamadi Maryam , Sadeghi Sedigheh , Zamani Zahra , Tabatabaie Fatemeh 
Published: February 2020

AbstractDue to side-effects and inefficiency of the drugs used in malaria treatment, finding alternative medicine with less side-effects has attracted much attention. In this regard, in the present study, nanocomposite synthesized and its effects on the metabolites of P. falciparum were investigated. Subsequent to synthesis of nanocomposites, characterization was carried out using nuclear magnetic resonance (NMR), liquid chromatography-mass spectrometry (LC-MS), scanning electron microscopy, dynamic light scattering and Fourier-transform infrared tests. Solubility and drug release were measured and its toxicity on Vero cell was assessed using the MTT assay. The antiparasitic effect of the nanocomposite on the metabolites of P. falciparum was investigated by 1H NMR spectroscopy. Among synthesized nanocomposites, the average size of 239 nm showed suitable solubility in water as well as slow drug release. The MTT assay showed no toxicity for Vero cell lines. Concentrations of 2.5 μg mL−1 of nanocomposite eliminated 82.6% of the total parasites. The most effected metabolic cycles were glyoxylate and dicarboxylate metabolism. In this study, 1H NMR spectroscopy was used with untargeted metabolomics to study the effect of the nanocomposite on P. falciparum. Playing an essential role in understanding drug-target interactions and characterization of mechanism of action or resistance exhibited by novel antiprotozoal drugs, can be achieved by targeting metabolic using LC-MS.
Salt, sediments and weathering environments in Bunger Hills
Authors: Gore Damian B. , Leishman Michelle R. 
Published: February 2020

AbstractTerrestrial environments at Bunger Hills, East Antarctica, vary from vegetation-rich, little-weathered rock surfaces retaining glacial polish and striations near the glacier and ice-sheet margins to salty, vegetation-poor, extensively weathered regions near to and downwind of marine bays and inlets. Weathering forms include tafoni and orientated pits, which record former wind directions. Although salts are found all over Bunger Hills, the strongly weathered area is coincident with the distribution of halite (NaCl) and thenardite (Na2SO4), both of which are derived from seawater and marine salt spray. Salts elsewhere in Bunger Hills are either subglacial calcium carbonates or rock weathering products including gypsum (CaSO4⋅2H2O) and a range of rarer minerals. These other salt minerals do not weather rocks and sediment. The distribution of halite and thenardite acts as a major control on the geomorphology, sediment geochemistry and biogeography of Bunger Hills.
N-terminal pro-B-type natriuretic peptide levels in children: comparison in cardiac and non-cardiac diseases
Authors: Kim Hyun Su , Choi Hee Joung 
Published: February 2020

AbstractBackground:N-terminal pro-B-type natriuretic peptide (NT-proBNP), a well-known marker of cardiac disease, may be elevated in acute infections and other non-cardiac diseases. The aim of this study was to evaluate NT-proBNP levels in cardiac and non-cardiac diseases and found out the patient’s clinical status that affects the NT-proBNP levels.Methods:NT-proBNP levels were measured in three groups of children: a cardiac disease group, an infectious disease group, and a non-cardiac, non-infectious disease group.Result:In total, 348 children were enrolled, including 134 patients (38.5%) with cardiac disease, 170 patients (48.9%) with infectious disease, and 44 patients (12.6%) with non-cardiac, non-infectious disease. The NT-proBNP level of the cardiac disease group (median: 548 pg/mL; range: 5–35,000 pg/mL) was significantly higher than that of the infectious disease group (median: 193 pg/mL; range: 10–35,000 pg/mL) and the non-cardiac, non-infectious disease group (median: 280 pg/mL; range: 6–35,000 pg/mL). Regarding clinical status, the NT-proBNP levels were significantly higher in patients who needed mechanical ventilation support, oxygen therapy, or inotropic medication or had a change in mental status than in other patients. However, the systemic inflammatory response syndrome and mortality were not related to the NT-proBNP level.Conclusion:Among heterogeneous group of children, NT-proBNP level can be a useful marker of cardiac disease. Furthermore, the NT-proBNP levels were related to patients’ clinical deteriorations, such as shock rather than the inflammatory status of patients.
Aortic regurgitation after closure of ventricular septal defect by transcatheter device: the long-term complication
Authors: Han Yuehu , Li Hongling , Zhu Hailong , Sun Guocheng , Yin Qiang , Gu Chunhu 
Published: February 2020

AbstractVentricular septal defect is the most common type of CHD, and transcatheter ventricular septal defect closure has been shown to be an alternative to surgical closure with acceptable mortality and morbidity as well as encouraging results. Short-term and mid-term follow-ups have indicated the safety and efficacy of transcatheter closure, but long-term follow-up results were rare. In this report, we first found that aortic regurgitation occurred in patients 9–12 years following transcatheter closure and regurgitation were gradually increased. The findings indicate that the long-term outcome of transcatheter closure of ventricular septal defect may not be as satisfied as expected.
Developing a conceptual framework for implementation science to evaluate a nutrition intervention scaled-up in a real-world setting
Authors: Sarma Haribondhu , D’Este Catherine , Ahmed Tahmeed , Bossert Thomas J , Banwell Cathy 
Published: February 2020

AbstractObjective:The aim of this paper is to identify and develop a comprehensive conceptual framework using implementation science that can be applied to assess a nutrition intervention in a real-world setting.Design:We conducted a narrative review using electronic databases and a manual search to identify implementation science frameworks, models and theories published in peer-reviewed journals. We performed a qualitative thematic analysis of these publications to generate a framework that could be applied to nutrition implementation science.Results:Based on this review, we developed a comprehensive framework which we have conceptualised as an implementation science process that describes the transition from the use of scientific evidence through to scaling-up with the aim of making an intervention sustainable. The framework consisted of three domains: Domain i – efficacy to effectiveness trials, Domain ii – scaling-up and Domain iii – sustainability. These three domains encompass five components: identifying an ‘effective’ intervention; scaling-up and implementation fidelity; course corrections during implementation; promoting sustainability of interventions and consideration of a comprehensive methodological paradigm to identify ‘effective’ interventions and to assess the process and outcome indicators of implementation. The framework was successfully applied to a nutrition implementation program in Bangladesh.Conclusions:Our conceptual framework built from an implantation science perspective offers a comprehensive approach supported by a foundational and holistic understanding of its key components. This framework provides guidance for implementation researchers, policy-makers and programme managers to identify and review an effective intervention, to scale it up and to sustain it over time.
Interevent Seismicity Statistics Associated With the 2018 Quasiperiodic Collapse Events at Kīlauea, HI, USA
Authors: Fildes Rebecca A. , Kellogg Louise H. , Turcotte Donald L. , Rundle John B. 
Published: February 2020

AbstractFollowing the Mw 6.9 Hawaiian earthquake on 4 May 2018, a remarkable quasiperiodic sequence of collapse events began at Halema'uma'u Crater at the summit of Kīlauea Volcano. The collapse events were associated with the drainage of magma from beneath the summit to the Lower East Rift Zone where fissure eruptions occurred. From 4 June 2018 to 2 August 2018 forty‐seven collapse events Mw 5.3 ± 0.1 occurred with the same temporal pattern of seismicity occurring between sequential pairs of collapse events. This paper focuses on this interevent seismicity pattern. Following a collapse event, there was a relatively quiescent period. This was followed by a sudden increase in seismicity, occurring at a nearly linear rate of 397 ± 96 earthquakes per day. These seismically active periods lasted until the next collapse event occurred. The pattern then repeated itself beginning again with postcollapse quiescence. We provide a statistical summary of this seismicity behavior by isolating the quiescent and active times to look at immediate precollapse and postcollapse activity. In mid‐June there were significant changes in the quiescent time lengths (decreased), the number of earthquakes during the interevent times (increased), and the rates of seismicity during the active times (increased). This type of interevent study could be conducted with other seismically well recorded, sequential caldera collapse events and also with other data types to look for potential physical explanations and an improved understanding of precollapse and postcollapse activity.