bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of cortical hemodynamic failure on both subsequent hemorrhagic stroke and effect of bypass surgery in hemorrhagic moyamoya disease: a supplementary analysis of the Japan Adult Moyamoya Trial
Authors: Takahashi Jun C. , Funaki Takeshi , Houkin Kiyohiro , Kuroda Satoshi , Fujimura Miki , Tomata Yasutake , Miyamoto Susumu 
Published: March 2020

OBJECTIVEHere, the authors aimed to determine whether the presence of cerebral hemodynamic failure predicts subsequent bleeding attacks and how it correlates with the effect of direct bypass surgery in hemorrhagic moyamoya disease.METHODSData from the Japanese Adult Moyamoya (JAM) Trial were used in this study: 158 hemispheres in 79 patients. A newly formed expert panel evaluated the SPECT results submitted at trial enrollment and classified the cortical hemodynamic state of the middle cerebral artery territory of each hemisphere into one of the following three groups: SPECT stage (SS) 0 as normal, SS1 as decreased cerebrovascular reserve (CVR), and SS2 as decreased CVR with decreased baseline blood flow. In the nonsurgical cohort of the JAM Trial, the subsequent hemorrhage rate during the 5-year follow-up was compared between the SS0 (hemodynamic failure negative) and SS1+2 (hemodynamic failure positive) groups. The effect of direct or combined direct/indirect bypass surgery on hemorrhage prevention was examined in each subgroup.RESULTSThe hemodynamic grade was SS0 in 59 (37.3%) hemispheres, SS1 in 87 (55.1%), and SS2 in 12 (7.6%). In the nonsurgical cohort, subsequent hemorrhage rates in the SS0 and SS1+2 groups were 12 cases per 1000 person-years and 67 cases per 1000 person-years, respectively. Kaplan-Meier analysis revealed that hemorrhagic events were significantly more common in the SS1+2 group (p = 0.019, log-rank test). Cox regression analysis showed that hemodynamic failure was an independent risk factor for subsequent hemorrhage (HR 5.37, 95% CI 1.07–27.02). In the SS1+2 subgroup, bypass surgery significantly suppressed hemorrhagic events during 5 years (p = 0.001, HR 0.16, 95% CI 0.04–0.57), with no significant effect in the SS0 group (p = 0.655, HR 1.56, 95% CI 0.22–11.10). Examination of effect modification revealed that the effect of surgery tended to differ nonsignificantly between these two subgroups (p = 0.056).CONCLUSIONSHemodynamic failure is an independent risk factor for subsequent hemorrhage in hemorrhagic moyamoya disease. Direct bypass surgery showed a significant preventive effect in the hemodynamically impaired hemispheres. Thus, hemodynamic failure, as well as previously proposed factors such as choroidal anastomosis, should be considered for the surgical indication in hemorrhagic moyamoya disease.Clinical trial registration no.: C000000166 (umin.ac.jp)
Subsecond EEG-fMRI analysis for presurgical evaluation in focal epilepsy
Authors: Ito Yuji , Maesawa Satoshi , Bagarinao Epifanio , Okai Yu , Nakatsubo Daisuke , Yamamoto Hiroyuki , Kidokoro Hiroyuki , Usui Naotaka , Natsume Jun , Hoshiyama Minoru , Wakabayashi Toshihiko , Sobue Gen , Ozaki Norio 
Published: March 2020

OBJECTIVE
The authors recently reported a novel subsecond analysis method of analyzing EEG–functional MRI (fMRI) to improve the detection rate of epileptic focus. This study aims to validate the utility of this method for presurgical evaluation in pharmacoresistant focal epilepsy.

METHODS
Among 13 patients with focal epilepsy undergoing presurgical examinations including simultaneous EEG-fMRI at 3T, 11 patients had interictal epileptiform discharges (IEDs) during fMRI. The authors used the sequence of topographic maps during the IEDs as a reference to obtain subsecond fMRI activation maps with the same temporal resolution as the EEG data, and constructed “spike-and-slow-wave-activation-summary” (SSWAS) maps that showed the activation frequency of voxels during IEDs. Clusters were defined by thresholding the SSWAS maps (voxel value > 10), and those containing voxels with the top 3 highest activation frequencies were considered significant. Significant hemodynamic responses using conventional event-related (ER) analysis and SSWAS maps were compared with the resection areas and surgical outcomes at 1 year after surgery.

RESULTS
Using ER analysis, 4 (36%) of 11 patients had significant hemodynamic responses. One of 4 patients had significant hemodynamic responses in the resection area and good surgical outcome. Using SSWAS maps, 10 (91%) of 11 patients had significant hemodynamic responses. Six of 10 patients had significant hemodynamic responses in the resection area, and 5 of the 6 patients achieved good surgical outcomes. The remaining 4 patients had significant hemodynamic responses distant from the resection area, and only 1 of the 4 patients achieved good surgical outcomes. The sensitivity, specificity, positive predictive value, and negative predictive value of SSWAS maps were 83.3%, 75.0%, 83.3%, and 75.0%, respectively.

CONCLUSIONS
This study demonstrated the clinical utility of SSWAS maps for presurgical evaluation of pharmacoresistant focal epilepsy. The findings indicated that subsecond EEG-fMRI analysis may help surgeons choose the resection areas that could lead to good surgical outcomes.
Impact of Medicaid insurance on outcomes following endoscopic transsphenoidal pituitary surgery
Authors: Younus Iyan , Gerges Mina , Schwartz Theodore H. , Ramakrishna Rohan 
Published: March 2020

OBJECTIVEDespite the rise of studies in the neurosurgical literature suggesting that patients with Medicaid insurance have inferior outcomes, there remains a paucity of data on the impact of insurance on outcomes after endonasal endoscopic transsphenoidal surgery (EETS). Given the increasing importance of complications in quality-based healthcare metrics, the objective of this study was to assess whether Medicaid insurance type influences outcomes in EETS for pituitary adenoma.METHODSThe authors analyzed a prospectively acquired database of EETS for pituitary adenoma from 2005 to 2018 at NewYork-Presbyterian Hospital, Weill Cornell Medicine. All patients with Medicaid insurance were identified. As a control group, the clinical, socioeconomic, and radiographic data of all other patients in the series with non-Medicaid insurance were reviewed. Statistical significance was determined with an alpha < 0.05 using Pearson chi-square and Fisher’s exact tests for categorical variables and the independent-samples t-test for continuous variables.RESULTSOf 584 patients undergoing EETS for pituitary adenoma, 57 (10%) had Medicaid insurance. The maximum tumor diameter was significantly larger for Medicaid patients (26.1 ± 12 vs 23.1 ± 11 mm for controls, p < 0.05). Baseline comorbidities including diabetes mellitus, hypertension, smoking history, and BMI were not significantly different between Medicaid patients and controls. Patients with Medicaid insurance had a significantly higher rate of any complication (14% vs 7% for controls, p < 0.05) and long-term cranial neuropathy (5% vs 1% for controls, p < 0.05). There were no statistically significant differences in endocrine outcome or vision outcome. The mean postoperative length of stay was significantly longer for Medicaid patients compared to the controls (9.4 ± 31 vs 3.6 ± 3 days, p < 0.05). This difference remained significant even when accounting for outliers (5.6 ± 2.5 vs 3.0 ± 2.7 days for controls, p < 0.05). The most common causes of extended length of stay greater than 1 standard deviation for Medicaid patients were management of perioperative complications and disposition challenges. The rate of 30-day readmission was 7% for Medicaid patients and 4.4% for controls, which was not a statistically significant difference.CONCLUSIONSThe authors found that larger tumor diameter, longer postoperative length of stay, higher rate of complications, and long-term cranial neuropathy were significantly associated with Medicaid insurance. There were no statistically significant differences in baseline comorbidities, apoplexy, endocrine outcome, vision outcome, or 30-day readmission.
Predictors of early postoperative epileptic seizures after awake surgery in supratentorial diffuse gliomas
Authors: Zanello Marc , Roux Alexandre , Zah-Bi Gilles , Trancart Bénédicte , Parraga Eduardo , Edjlali Myriam , Tauziede-Espariat Arnault , Sauvageon Xavier , Sharshar Tarek , Oppenheim Catherine , Varlet Pascale , Dezamis Edouard , Pallud Johan 
Published: March 2020

OBJECTIVEFunctional-based resection under awake conditions had been associated with a nonnegligible rate of intraoperative and postoperative epileptic seizures. The authors assessed the incidence of intraoperative and early postoperative epileptic seizures after functional-based resection under awake conditions.METHODSThe authors prospectively assessed intraoperative and postoperative seizures (within 1 month) together with clinical, imaging, surgical, histopathological, and follow-up data for 202 consecutive diffuse glioma adult patients who underwent a functional-based resection under awake conditions.RESULTSIntraoperative seizures occurred in 3.5% of patients during cortical stimulation; all resolved without any procedure being discontinued. No predictor of intraoperative seizures was identified. Early postoperative seizures occurred in 7.9% of patients at a mean of 5.1 ± 2.9 days. They increased the duration of hospital stay (p = 0.018), did not impact the 6-month (median 95 vs 100, p = 0.740) or the 2-year (median 100 vs 100, p = 0.243) postoperative Karnofsky Performance Status score and did not impact the 6-month (100% vs 91.4%, p = 0.252) or the 2-year (91.7 vs 89.4%, p = 0.857) postoperative seizure control. The time to treatment of at least 3 months (adjusted OR [aOR] 4.76 [95% CI 1.38–16.36], p = 0.013), frontal lobe involvement (aOR 4.88 [95% CI 1.25–19.03], p = 0.023), current intensity for intraoperative mapping of at least 3 mA (aOR 4.11 [95% CI 1.17–14.49], p = 0.028), and supratotal resection (aOR 6.24 [95% CI 1.43–27.29], p = 0.015) were independently associated with early postoperative seizures.CONCLUSIONSFunctional-based resection under awake conditions can be safely performed with a very low rate of intraoperative and early postoperative seizures and good 6-month and 2-year postoperative seizure outcomes. Intraoperatively, the use of the lowest current threshold producing reproducible responses is mandatory to reduce seizure occurrence intraoperatively and in the early postoperative period.
Immediate postoperative measurement of thyroid-stimulating hormone as an early predictor of remission in thyroid-stimulating hormone–secreting pituitary adenomas
Authors: Kim Soo Heon , Ku Cheol Ryong , Na Minkyun , Yoo Jihwan , Kim Woohyun , Jung In-Ho , Kim Kyung Won , Moon Ju Hyung , Kim Daham , Lee Eun Jig , Kim Sun Ho , Kim Eui Hyun 
Published: March 2020

OBJECTIVEThyroid-stimulating hormone (TSH)–secreting pituitary adenoma (TSHoma) is a rare type of pituitary adenoma; thus, little is known about TSHomas. The purpose of this study was to analyze clinical characteristics and therapeutic outcomes of TSHomas based on a single-center experience. The authors also searched for reliable preoperative and early postoperative factors that could predict long-term endocrinological remission.METHODSThe clinical, radiological, and pathological characteristics and surgical and endocrinological outcomes of 31 consecutive cases of TSHomas that were surgically treated between 2005 and 2017 were reviewed retrospectively. Preoperative factors were evaluated for their ability to predict long-term remission by comparing remission and nonremission groups. TSH and free thyroxine levels were measured at 2, 6, 12, 18, and 24 hours after surgery to determine whether they could predict long-term remission.RESULTSGross-total removal of tumor was achieved in 28 patients (90.3%), and 26 patients (83.9%) achieved endocrinological remission by surgery alone based on long-term endocrinological follow-up (median 50 months, range 32–81 months). The majority of the tumors were solid (21/31, 67.7%), and en bloc resection was possible in 16 patients (51.6%). Larger tumor size and tumor invasion into cavernous sinus and sphenoid sinus were strong predictors of lower rates of endocrinological remission. Immediate postoperative TSH level at 12 hours after surgery was the strongest predictor, with a 0.62 μIU/mL cutoff. Postoperative complications included CSF rhinorrhea in one patient and epistaxis in another patient, who underwent additional surgical treatment for the complications.CONCLUSIONSTumor size and extent are major prognostic factors for both extent of resection and endocrinological remission. The consistency of TSHomas was more likely to be solid, which makes extracapsular dissection more feasible. Long-term remission of TSHomas could be predicted even during the early postoperative period.
Sphenoparietal sinus transposition technique: optimization of the surgical corridor with preservation of prominent bridging veins between the brain and the cranial base during aneurysm clipping via the pterional approach
Authors: Niibo Takeya , Takizawa Katsumi , Sakurai Jurou , Takebayashi Seizi , Koizumi Hiroyasu , Kobayashi Toru , Kobayashi Rina , Kuris Kouta , Gotou Syusuke , Tsuchiya Ryousuke , Kamiyama Hiroyasu 
Published: March 2020

OBJECTIVEThe sylvian bridging veins between the brain and the dura on the inner surface of the sphenoid wing can restrict brain retraction for widening of the lateral retrocarotid space during clipping surgery for internal carotid artery (ICA)–posterior communicating artery (PCoA) and basilar apex (BX) aneurysms. In such cases, the authors perform extradural anterior clinoidectomy with peeling of the temporal dura propria from the periosteal dura and inner cavernous membrane around the superior orbital fissure, with the incision of the dura mater stretching from the base of the temporal side to just before the distal dural ring of the ICA (termed by the authors as the sphenoparietal sinus transposition [SPST] technique). This technique displaces the bridging segment of the sylvian vein posteriorly and enables widening of the surgical space without venous injury. In this study, the authors observed the operative nuances and investigated the usefulness of this technique.METHODSThe authors retrospectively reviewed the medical charts of 66 consecutive patients with ICA-PCoA and BX aneurysms between January 2016 and July 2018. This technique was performed in 8 patients (5 patients with PCoA aneurysms and 3 with BX aneurysms) in whom the bridging segments of the sylvian veins between the brain and the skull base restricted brain retraction for widening of the surgical space. The surface areas of the lateral retrocarotid space and the aneurysm were measured at the most visible working angle before and after the SPST technique was performed.RESULTSWith the use of the SPST technique, an adequate surgical space for aneurysm clipping was obtained with preservation of the bridging veins in all patients. The mean surface areas of the lateral retrocarotid space (p = 0.002) and aneurysm (p = 0.001) were significantly increased from 18.3 ± 18.8 and 2.8 ± 2.5 cm2 before to 64.2 ± 21.1 and 20.9 ± 20.6 cm2, respectively, after the SPST technique was performed.CONCLUSIONSThe SPST technique enables displacement of the bridging segments of the sylvian veins without venous injury and enables widening of the surgical space around the lateral retrocarotid area.
Development and validation of prediction scores for nosocomial infections, reoperations, and adverse events in the daily clinical setting of neurosurgical patients with cerebral and spinal tumors
Authors: Lohmann Sebastian , Brix Tobias , Varghese Julian , Warneke Nils , Schwake Michael , Suero Molina Eric , Holling Markus , Stummer Walter , Schipmann Stephanie 
Published: March 2020

OBJECTIVE
Various quality indicators are currently under investigation, aiming at measuring the quality of care in neurosurgery; however, the discipline currently lacks practical scoring systems for accurately assessing risk. The aim of this study was to develop three accurate, easy-to-use risk scoring systems for nosocomial infections, reoperations, and adverse events for patients with cerebral and spinal tumors.

METHODS
The authors developed a semiautomatic registry with administrative and clinical data and included all patients with spinal or cerebral tumors treated between September 2017 and May 2019. Patients were further divided into development and validation cohorts. Multivariable logistic regression models were used to develop risk scores by assigning points based on β coefficients, and internal validation of the scores was performed.

RESULTS
In total, 1000 patients were included. An unplanned 30-day reoperation was observed in 6.8% of patients. Nosocomial infections were documented in 7.4% of cases and any adverse event in 14.5%. The risk scores comprise variables such as emergency admission, nursing care level, ECOG performance status, and inflammatory markers on admission. Three scoring systems, NoInfECT for predicting the incidence of nosocomial infections (low risk, 1.8%; intermediate risk, 8.1%; and high risk, 26.0% [p < 0.001]), LEUCut for 30-day unplanned reoperations (low risk, 2.2%; intermediate risk, 6.8%; and high risk, 13.5% [p < 0.001]), and LINC for any adverse events (low risk, 7.6%; intermediate risk, 15.7%; and high risk, 49.5% [p < 0.001]), showed satisfactory discrimination between the different outcome groups in receiver operating characteristic curve analysis (AUC ≥ 0.7).

CONCLUSIONS
The proposed risk scores allow efficient prediction of the likelihood of adverse events, to compare quality of care between different providers, and further provide guidance to surgeons on how to allocate preoperative care.
IMPROVING INDONESIAN STUDENTS’ RHETORICAL SKILLS THROUGH SUGGESTOPEDIA
Authors: Suprapto Suprapto , Kurniawan Rio 
Published: March 2020

This study aims to improve students’ rhetoric skills of a class at the Indonesian Education Study Program Faculty of Teacher Traning and Education University of Bengkulu, in the academic year of 2018/2019. This research uses a qualitative approach with descriptive method to describe the conditions of rhetoric learning using the method sugestopedia for students from A class of Indonesian Education Study Program Faculty of Teacher Training and Education University of Bengkulu, academic year 2018/2019 was employed. Based of the research results in the first cycle there are advantages in the application of the suggestopedia method in learning speaking skill, namely; 1. The existence of student confidence and motivation in learning rhetoric. 2. By using the Suggestopedia Method, students can feel comfortable in learning, so that the imagination of students is more better. In the research conducted in the first cycle there are also deficiencies, namely the example of rhetoric given to students using simple aspects as that students tend to rhetoric based on the aspects used in the example of the rhetoric. The results of the data analysis of the second cycle of learning with the application of the suggestopedia method, obtained data; 37 students scored above 70 and mastery learning 92.5%. As the researcher stopped this class action research until the second cycle, because the research indicators had been reached.
Review of Leadership Styles in Perspective of Dynamic Capabilities: An Empirical Research on Managers in Manufacturing Firms
Authors: AKKAYA Bülent 
Published: March 2020

Firms need to adapt to
changes in both their internal and external environments and create new systems
that let them focus on new trends, identify improvements, try to guess their
potential impact on their management and manufacturing system. They try to learn quickly how to implement
changes to their standard operating procedures. A wide range of factors affects
this procedure. To achieve this, they should be managed by modern leaders. The
purpose of this research is to investigate the leadership dimensions and a
related framework for assessing leadership styles, in relation to the context
in which the leader works in dynamic environment. Furthermore, the purpose of
this study was to examine the relative impact of different types of leadership
on firms’ dynamic capabilities. Research is reported on data from a large
sample of leaders and managers (n 214) from a range of private manufacturing
organizations in West of Turkey. Content analyses, one of the methods of quality analysis, and
MAXMaps were performed in context of top-down &amp;bottom-up confirmation
method. SPSS and Maxqda analyses program was used to analyze data. The
results show that agile and transformational leaders can enhance firms’ dynamic
capabilities indirectly or indirectly by creating an organizational atmosphere
where employees and followers are encouraged, motivated, inspired to be a role
model, open to change, and innovation. However, it was found that the link
between dynamic capabilities of a firm and hubristic and autocratic leadership
was slightly positive.
"Pokaz rybek magnetycznych”: Widowiskowa popularyzacja wiedzy w Gimnazjum/Liceum Wołyńskim w Krzemieńcu
Authors: Buczek Katarzyna 
Published: March 2020

Popularyzacja wiedzy w Gimnazjum/Liceum Wołyńskim w Krzemieńcu (1805–1832) była jedną z form działalności nauczycieli. Cieszyła się dużą popularnością wśród okolicznej ludności, nie tyle jednak ze względu na walor poznawczy, co na aspekt widowiskowy. Prowadzona była w ciągu roku szkolnego oraz podczas egzaminów publicznych (popisów) na zakończenie nauki. Liczną publiczność gromadziły pokazy eksperymentów, prezentowane przez profesora fizyki Karola Jentza, a także nauka ogrodnictwa praktycznego prowadzona w ogrodzie botanicznym przez ogrodnika Karola Witzella. Jednak do tej działalności władze szkolne miały stosunek ambiwalentny. Z jednej strony doceniano wysiłki nauczycieli, z drugiej widowiskowość pokazów budziła poważne zastrzeżenia czy wręcz niechęć zwierzchników.
W rytmie kół: Zapiski Heleny Modrzejewskiej z amerykańskiego tournée w 1893 roku
Authors: Jarząbek-Wasyl Dorota 
Published: March 2020

Artykuł jest analizą bieżącej edycji diariusza Heleny Modrzejewskiej, który został opatrzony komentarzami dotyczącymi samej jego treści: opisywanych przez Modrzejewską wydarzeń pierwszych sześciu tygodni 1893 roku, pojawiających się w nich postaci, ich relacji z aktorką, przedstawień i sztuk teatralnych, jak również wydawniczych losów Dziennika. Noty towarzyszące tekstowi sytuują go w kontekście nie tylko kolejnych edycji, ale również spisanych po latach pamiętników Modrzejewskiej, do których aktorka celowo nie włączyła diariusza. Publikacja jest pierwszą edycją genetyczną, kładącą szczególny nacisk na proces powstawania rękopisu, nanoszone na niego korekty tak przez samą autorkę, jak i późniejszych edytorów, oraz zmiany dokonywane przez wydawców.