bluuebunny/crossref_metadata_2025_split huggingface dataset:
Progressive amnestic cognitive impairment in a middle-aged patient with developmental language disorder: a case report
Authors: Takaya Masahiko , Ishii Kazunari , Kiguchi Kaori , Saigoh Kazumasa , Shirakawa Osamu 
Published: September 2020

Abstract
Background
Developmental disorder and dementia in older adults have been considered unrelated clinical entities because their timing of diagnosis differs greatly; however, recent studies have suggested an association between them. This case describes a middle-aged patient with language disorder exhibiting progressive amnestic cognitive impairment.

Case Presentation
A 44-year-old Japanese man with long-term language dysfunction presented for his first-ever medical evaluation at age 36 years. Although his conversational ability had been impaired since childhood, he was able to graduate from secondary school and gain unskilled employment. At age 36 years, however, his workplace environment became more stressful, which led to behavioral problems that necessitated medical consultation. He consulted two psychiatrists in vain. At age 44 years, the third attending psychiatrist examined him in detail. The major component of his language disorder was amnestic cognitive impairment in the language domain as shown by logical memory subtests of the Wechsler Memory Scale–Revised. Magnetic resonance imaging showed normal findings for his age and no small vessel disease. Global cerebral hypoperfusion versus cerebellar blood flow was shown on (123I) iodoamphetamine single-photon emission computed tomography, and amyloid-β deposition was negative on positron emission tomography with 11C-Pittsburgh compound B. Pathologic tau accumulation was negative on 18F-THK5351 positron emission tomography imaging. Laboratory tests show no infections, no vitamin deficiencies, and no other diseases that may cause dementia. Clinical features, results of neurocognitive tests and neuroimaging studies showed no well-known neurodegenerative diseases. Collectively, he was diagnosed with language disorder based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria. Over a 2-year follow-up period, amnestic cognitive impairment in visual and language domains progressed in parallel with global cerebral hypoperfusion.

Conclusion
This case suggests a possible link between language disorder as defined by Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria and progressive amnestic cognitive impairment in middle age, which may ultimately lead to dementia, derived from a neurodegenerative disease.
Are antenatal interventions effective in improving multiple health behaviours among pregnant women? A systematic review protocol
Authors: Hollis Jenna L. , Doherty Emma , Dray Julia , Tremain Danika , Hunter Mandy , Takats Karen , Williams Christopher M. , Murray Henry , Pennell Craig E. , Tully Belinda , Wiggers John , Daly Justine B. , Kingsland Melanie 
Published: September 2020

Abstract
Background
Maternal behaviours in pregnancy associated with adverse pregnancy, birth and health outcomes include tobacco smoking, poor nutrition, alcohol consumption and low physical activity, collectively referred to as the SNAP risk factors. Due to the high prevalence, co-occurrence and possible interactive health effects of such health behaviours in pregnancy, antenatal interventions that support pregnant women to improve multiple SNAP behaviours have a greater potential impact on the health outcomes of women and their children than interventions addressing single behaviours. The objective of this review is to determine the effectiveness of interventions delivered as part of antenatal care that aim to improve multiple SNAP behaviours among pregnant women.

Methods
Seven electronic databases will be searched for potentially eligible studies. Eligible studies will include those where pregnant women are attending antenatal care. Studies that examine the effect of an intervention that addresses multiple SNAP behaviours (≥ 2 behaviours) during pregnancy and are delivered or instigated through antenatal care in a healthcare service will be included. Systematic reviews of randomised controlled trials (RCTs), RCTs, cluster RCTs, stepped-wedge RCTs and non-randomised control trials will be eligible. Studies that include a no-intervention control, wait-list control group, standard/usual care, or another active single behavioural intervention (e.g. addressing one behaviour only) will be considered. Two independent reviewers will conduct study screening, data extraction and risk of bias assessment. Discrepancies will be resolved by consensus or a third reviewer if required. A random effects model will be used to synthesise the results. Alternative synthesis methods will be investigated in instances where a meta-analysis is not appropriate, such as summarising effect estimates, combining P values, vote counting based on direction of effect, or synthesis in narrative form.

Discussion
The review will synthesise the evidence on the effect of interventions that address multiple SNAP behaviours in antenatal care and will help researchers, policy-makers and health services to develop and deliver best practice integrated models of antenatal care that have the potential to impact on both the short- and long-term health outcomes for women and their children.

Systematic review registration
PROSPERO CRD42018095315
Relationship between volume and outcome for gastroschisis: a systematic review protocol
Authors: Morche Johannes , Mathes Tim , Jacobs Anja , Wessel Lucas , Neugebauer Edmund A. M. , Pieper Dawid 
Published: September 2020

Abstract
Background
Gastroschisis is a congenital anomaly that needs surgical management for repositioning intestines into the abdominal cavity and for abdominal closure. Higher hospital or surgeon volume has previously been found to be associated with better clinical outcomes for different especially high-risk, low volume procedures. Therefore, we aim to examine the relationship between hospital or surgeon volume and outcomes for gastroschisis.

Methods
We will perform a systematic literature search from inception onwards in Medline, Embase, CENTRAL, CINAHL, and Biosis Previews without applying any limitations. In addition, we will search trial registries and relevant conference proceedings. We will include (cluster-) randomized controlled trials (RCTs) and prospective or retrospective cohort studies analyzing the relationship between hospital or surgeon volume and clinical outcomes. The primary outcomes will be survival and mortality. Secondary outcomes will be different measures of morbidity (e.g., severe gastrointestinal complications, gastrointestinal dysfunctions, and sepsis), quality of life, and length of stay. We will systematically assess risk of bias of included studies using RoB 2 for individually or cluster-randomized trials and ROBINS-I for cohort studies, and extract data on the study design, patient characteristics, case-mix adjustments, statistical methods, hospital and surgeon volume, and outcomes into standardized tables. Title and abstract screening, full text screening, critical appraisal, and data extraction of results will be conducted by two reviewers independently. Other data will be extracted by one reviewer and checked for accuracy by a second one. Any disagreements will be resolved by discussion. We will not pool results statistically as we expect included studies to be clinically and methodologically very diverse. We will conduct a systematic synthesis without meta-analysis and use GRADE for assessing the certainty of the evidence.

Discussion
Given the lack of a comprehensive summary of findings on the relationship between hospital or surgeon volume and outcomes for gastroschisis, this systematic review will put things right. Results can be used to inform decision makers or clinicians and to adapt medical care.

Systematic review registration
Open Science Framework (DOI: 10.17605/OSF.IO/EX34M; 10.17605/OSF.IO/HGPZ2)
The association between analgesic drug use in pregnancy and neurodevelopmental disorders: protocol for an umbrella review
Authors: Kwok Janell , Hall Hildigunnur Anna , Murray Aja Louise , Auyeung Bonnie 
Published: September 2020

Abstract
Background
Maternal prenatal health has been shown to be an important influence on children’s developmental outcomes, which has led to an increased emphasis on providing more information to support clinical decisions in pregnancy. Several systematic reviews suggest that analgesic drug use during pregnancy may have neurodisruptive properties. However, no firm conclusions have yet been drawn on the associations between prenatal analgesic drug use and children’s long-term development of neurodevelopmental disorders such as autism spectrum disorder (ASD) or attention deficit hyperactivity disorder (ADHD). Therefore, an umbrella review is proposed for the purpose of examining the associations between maternal analgesic drug use during pregnancy and diagnoses of neurodevelopmental disorders.

Methods
Included systematic reviews will consist of studies examining the effect of maternal prenatal analgesic drug use, specifically ibuprofen, acetaminophen, aspirin, naproxen, diclofenac, and ketoprofen, on children’s neurodevelopmental disorder status. Examined drugs were restricted to those readily accessible and frequently used by pregnant women, and with characteristics that allow them to cross the placenta and directly affect fetal development. Outcomes will be restricted to formal clinical diagnoses of ASD and/or ADHD. Two reviewers will independently identify eligible reviews from six databases (e.g., PubMed, EMBASE, PsychINFO) from inception dates of databases to the date of data extraction, and conduct manual searches of reference lists, consultation with field experts, and scan of pre-print archives. Extracted data will also include short qualitative summaries by both reviewers. As part of quality assessment, a standardized measurement tool to assess systematic reviews (AMSTAR 2) will be used. A narrative synthesis is proposed to integrate findings from different, potentially methodologically heterogeneous, studies.

Discussion
This umbrella review of associations between maternal prenatal use of analgesic drugs and children’s neurodevelopmental disorders could allow for firmer conclusions to be drawn through the synthesis of all relevant published research. The synthesis of findings using high-quality evidence could provide more accurate healthcare information on the long-term effects of analgesic drugs on neurodevelopment, to better guide future clinical decisions during pregnancy. This review will also allow gaps and methodological differences in the literature to be identified, informing recommendations for future research.

Systematic review registration
PROSPERO CRD42020179216.
SD2PA: a fully safe driving and privacy-preserving authentication scheme for VANETs
Authors: Alfadhli Saad Ali , Lu Songfeng , Fatani Abdulaziz , Al-Fedhly Haider , Ince Mahmut 
Published: September 2020

AbstractThe basic idea behind the vehicular ad-hoc network (VANET) is the exchange of traffic information between vehicles and the surrounding environment to offer a better driving experience. Privacy and security are the main concerns for meeting the safety aims of the VANET system. In this paper, we analyse recent VANET schemes that utilise a group authentication technique and found important vulnerabilities in terms of driving safety. These systems also suffer from vulnerabilities in terms of management efficiency and computational complexity. To defeat these problems, we propose a lightweight scheme, SD2PA, based on a general hash function for VANET. The proposed scheme overcomes the non-safe driving problem that resulted from the critical driving area. Moreover, the vehicle authentication is only done once by the VANET system administrator during the vehicle’s moving, so the authentication redundancy for the entire system is reduced and system management efficiency is enhanced. The SD2PA scheme also provides anonymity to protect the vehicle’s privacy, unless an important action needs to be taken against a malicious vehicle. A deep computational cost and communicational overhead analysis indicates that SD2PA is better than related schemes, as well as efficiently meeting VANET’s security and privacy needs.
The study of the causal relationship between innovativeness and entrepreneurial intention among undergraduate students
Authors: Wathanakom Narubodee , Khlaisang Jintavee , Songkram Noawanit 
Published: September 2020

AbstractIn recent years, entrepreneurs have become key drivers of business growth worldwide, since that time, entrepreneurial education has subsequently been garnering an increased level of interest. Entrepreneurship is considered to be a combination of both art and science, used to create value when targeting customers; however, there appears to be a myth when it comes to the recipe required for success. It was discovered by The Office of Small and Medium Enterprise Promotion that less than 10% of Thai small and medium entrepreneurial businesses were successful, while the global rate of success is close to 5 times higher than that of Thailand. Therefore, a better understanding of key success factors is necessary going forward. Typically, an entrepreneur’s journey starts with entrepreneurial intention, opportunity recognition, business initiative creation, and resource assembly, if they are to start their venture successfully. Entrepreneurial intention is a prerequisite to entrepreneurial behavior, based on the theory of planned behavior. Subsequently, scholars are interested in the key factors which drive entrepreneurial intention. While innovativeness has been proven to be one of the critical factors within certain groups of the population, there is little empirical data on the causal relationship between innovativeness and entrepreneurial intention amongst undergraduate students. As such, this study has two main objectives: (1) to explore factors influencing innovativeness, attitudes towards entrepreneurship and the entrepreneurial intentions of undergraduate students, and (2) to understand the causal relationship between innovativeness and entrepreneurial intentions among undergraduate students. The population of the study is comprised of undergraduate students from public universities and 330 effective responses were received in the survey. Based on the findings from confirmatory analysis and multiple regression, the empirical data is consistent with the theoretical measurement model for both innovativeness and entrepreneurial intention and (2) innovativeness can effectively predict entrepreneurial intention among undergraduate students.
Psychometric properties of instruments assessing exercise in patients with eating disorders: a systematic review
Authors: Harris Astrid , Hay Phillipa , Touyz Stephen 
Published: September 2020

AbstractBackgroundResearch has identified factors specific to exercise in eating disorder patients such as affect regulation and compulsivity. Existing measures of exercise behaviour which were not originally designed for eating disorder patients may not adequately assess these factors. The aim of this systematic review is to identify and assess the psychometric properties of all self-report measures of exercise designed to be used with eating disorder patients.MethodA systematic review was conducted following the PRISMA guidelines. MedLine, Scopus and PsycINFO were systematically searched. A total of 12 studies examining two measures, the Exercise and Eating Disorders and the Compulsive Exercise Test, met inclusion criteria.ResultsValidation studies showed promising results for both tests and established internal consistency, concurrent and convergent validity, and construct validity. The factor structure of the Compulsive Exercise Test was not confirmed in the majority of the studies included in this review, while there are only two studies conducting factor analysis on the Exercise and Eating Disorders.ConclusionThe two measures identified by this systematic review represent the current research on measures of compulsive exercise for eating disorder patients. Further research is needed to confirm a factor structure and validate both the Compulsive Exercise Test and the Exercise and Eating Disorders in more diverse clinical samples.
Correlates of avifaunal diversity along the elevational gradient of Mardi Himal in Annapurna Conservation Area, Central Nepal
Authors: Pandey Naresh , Khanal Laxman , Chalise Mukesh Kumar 
Published: September 2020

AbstractBackgroundPatterns of biological diversity and richness can vary along the elevational gradients among mountain systems making it difficult to conclude the general pattern. The drivers of such pattern are also poorly known in the southern flank of the Himalaya due to limited studies. Therefore, we assessed the species richness, seasonal patterns and drivers of avian diversity along an elevational gradient on Mardi Himal trekking trail, a newly open tourist route in Annapurna Conservation Area of the central Himalaya.MethodsTwo surveys (winter and summer seasons of 2019) were conducted from the bank of Seti-Gandaki River confluence (1030 m above sea level, asl) up to the Low Camp (3050 m asl) of the Mardi Himal. The point count method was employed in every 100 m rise in the elevation. Diversity indices were calculated and bird abundance data on species, sites, seasons and environmental variables were analyzed. Generalized linear model, polynomial regression and ordinary least square regression were performed to examine the importance of environmental factors in shaping the avian richness pattern.ResultsA total of 673 individuals of birds belonging to 112 species, of which 72 in winter and 80 in summer, were recorded. We observed a hump-shaped pattern of the overall species richness along the elevational gradient. The richness pattern remained consistent even when explored by season, for winter and summer separately. Diversity indices were found higher during the summer. Elevation and mean monthly temperature in both seasons showed non-linear relation with avian species richness. Precipitation exhibited positive association in summer whereas the same in winter was negatively correlated with avian species richness. Distance to the nearest water source and the nearest human settlement were negatively correlated with the richness of birds. Small-ranged and insectivorous birds were under the strong influence of gradients on climatic variables like temperature and precipitation.ConclusionsWe conclude that the combined effects of multiple factors such as area, gradients of climate (i.e. temperature and precipitation), resource availability and disturbance play an important role in bird diversity and richness pattern along an elevational gradient of a montane environment in Mardi Himal.
Variation in abundance and habitat relationship of three understory insectivorous birds in a disturbed landscape of Neotropical dry forest of Colombia
Authors: Loaiza Camilo , Montenegro Olga L. , King David , Spínola Manuel , Palacio Lilibeth Arinda , Rudas Agustín 
Published: September 2020

AbstractBackgroundEvaluating relationships between avian populations and their habitat is important for understanding the biology of these species and for management decisions that improve the effectiveness of restoration practices. We investigated how habitat variation along a disturbance gradient affected the abundance of three insectivorous bird species, White-bellied Antbird (Myrmeciza longipes), Barred Antshrike (Thamnophilus doliatus), and Pale-breasted Spinetail (Synallaxis albescens) in a Neotropical dry forest remnant in central Colombia.MethodsThe study area, which is located in Magdalena Valley, is under ecological restoration after the construction of the “El Quimbo” hydroelectric dam, with a gradient of habitat conditions, from relatively advanced secondary growth to recently disturbed areas. We conducted bird surveys and quantified the habitat conditions from June 2018 to June 2019. We compared the relative abundance of the birds among the three zones with increasing disturbance and modeled the relationship between the bird abundance with the micro- and landscape-habitat conditions, with Poisson generalized linear model regression.ResultsThe relative abundance of the three bird species varied according to the habitat features and disturbance level. The abundance of White-bellied Antbirds was higher in forests and thickets than shrubland fragments; Barred Antshrike was more abundant in shrubland and thickets than in forest fragments, and Pale-breasted Spinetail had the highest abundance in shrubland and the lowest in forest fragments. The abundance of both White-bellied Antbird and Pale-breasted Spinetail did not differ among zones with different levels of disturbance, while the abundance of Barred Antshrike decreased in zones with more disturbance.ConclusionsThere were significant differences in the habitat relationships of the three understory insectivorous species along the disturbance gradient, although these species were within the same trophic group. These bird species preferred different stages of habitat succession and responded to different habitat and landscape features. Increasing forest fragment areas and decreasing the amount of edge would be useful restoration priorities for these and other similar avian species in this study area.
Implant primary stability depending on protocol and insertion mode — an ex vivo study
Authors: Staedt Henning , Kämmerer Peer W. , Goetze Elisabeth , Thiem Daniel G. E. , Al-Nawas Bilal , Heimes Diana 
Published: September 2020

Abstract
Background
Dental implant primary stability is thought to be a fundamental prerequisite for the long-term survival and success. The aim of this study was to analyze the influence of protocol and insertion mode on dental implant stability ex vivo. One hundred and twenty implants were inserted either manually or machine-driven into porcine mandibles by a standard or over-dimensioned protocol. Dental implant stability was measured via resonance frequency analysis (RFA), insertion torque (IT), and torque out (TO).

Results
Statistically significant higher IT and TO values were seen after standard protocol insertion (p < 0.05), whereas manual and machine-driven insertion mode showed equivalent values.

Conclusions
The over-dimensioned protocol exceeded the primary stability values recommended for immediate implant insertion; therefore, it could be recommended as well.