bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thyroglobulin Antibodies as a Prognostic Factor in Papillary Thyroid
Carcinoma Patients with Indeterminate Response After Initial
Therapy
Authors: Landenberger Giullia Menuci Chianca , de Souza Salerno Marianna Lins , Golbert Lenara , de Souza Meyer Erika Laurini 
Published: September 2020

AbstractThe clinical outcome of papillary thyroid carcinoma (PTC) patients with an
indeterminate response after initial therapy is reported to be intermediate,
between incomplete and excellent responses. This study evaluated the outcomes of
PTC patients with indeterminate response after initial therapy. It was further
determined whether the indeterminate findings predicted outcomes more precisely.
Patients were further classified into 3 groups based on risk of structural
persistence/recurrence: Tg group: detectable thyroglobulin,
negative antithyroglobulin antibody, regardless nonspecific imaging findings;
TgAb group: positive antithyroglobulin antibody, regardless
thyroglobulin levels and nonspecific imaging findings, and Image group:
nonspecific findings on neck ultrasonography or faint uptake in the thyroid bed
on whole-body scan, undetectable thyroglobulin and negative antithyroglobulin
antibody. Sixty-six patients aged 44.1±12.7 years were studied, of whom
58 (87.9%) were females. All patients underwent total thyroidectomy, and
52 patients (78.8%) received radioiodine. After 5.7 years
(P25–75 2.6–9.75 years) of follow-up, most patients
(89.4%) were reclassified as having an excellent response or remained in
the indeterminate response to therapy. Structural recurrence/persistence
disease was detected in 7 (10.6%) patients. The
persistence/recurrence rate in groups were as follow: Tg,
2.63%; TgAb, 31.25%; Image, 8.3%
(p=0.007). The 10-years disease-free survival rate in the TgAb group was
significantly reduced (p=0.022). Our results suggest that patients with
PTC and indeterminate response due to positive serum antithyroglobulin antibody
have more risk of development of structural disease. These findings suggest a
more individualized follow-up strategy for patients with an indeterminate
response.
Comparison of Subxiphoid and Intercostal Uniportal Thoracoscopic Thymectomy for Nonmyasthenic Early-Stage Thymoma: A Retrospective Single-Center Propensity-Score Matching Analysis
Authors: Liu Zhengcheng , Yang Rusong 
Published: September 2020

Abstract
Objective The aim of this study was to compare early outcome between intercostal uniportal video-assisted thoracoscopic surgery (IU-VATS) versus subxiphoid uniportal video-assisted thoracoscopic surgery (SU-VATS) in thymectomy for non-myasthenic early-stage thymoma.
Method Retrospective analysis of 76 cases completed in our hospital from May 2018 to September 2019 with subxiphoid uniportal thoracoscopic thymectomy; a single incision of ∼3 cm was made ∼1 cm under the xiphoid process. The control group included 213 patients who received intercostal uniportal thoracoscopic thymectomy from August 2015, and propensity score matching was conducted. All patients who were clinically diagnosed with thymic tumor before surgery were treated with thymectomy. Perioperative outcomes between SU-VATS (n = 76) and IU-VATS, n = 76 were compared.
Result After propensity score matching, there were no statistically significant differences between the two groups in terms of age, gender, disease stage, maximal tumor size, or other baseline demographic and clinical variables. All operation was successfully completed; there were no significant differences in the operative time (88 vs. 81 minutes, p = 0.63), intraoperative blood loss (55 vs. 46 mL, p = 0.47), postoperative drainage time (2.2 vs. 2.5 days, p = 0.72), and postoperative hospital stay (3.2 vs. 3.4 days, p = 0.78) between the two groups. The visual analog scale (VAS) on postoperative days 1, 3, 7, and 30 was less in the SU-VATS group than that in the IU-VATS group. The VAS on days 60 and 180 did not differ significantly between the two groups.
Conclusion Thymectomy using SU-VATS is a feasible procedure; it might reduce early postoperative pain and lead to faster recovery.
Pelvic Floor Nonrelaxation: Approach to Evaluation and Treatment
Authors: Kaplan Jennifer A. , Simianu Vlad V. 
Published: September 2020

AbstractDyssynergic defecation can be a complex, burdensome condition. A multidisciplinary approach to these patients is often indicated based on concomitant pathology or symptomatology across the pelvic organs. Escalating treatment options should be based on shared decision making and include medical and lifestyle optimization, pelvic floor physical therapy with biofeedback, Botox injection, sacral neuromodulation, rectal irrigation, and surgical diversion.
Ventral Rectopexy
Authors: Loh Kenneth C. , Umanskiy Konstantin 
Published: September 2020

AbstractRectal prolapse is a debilitating condition that often results in impaired quality of life. Posterior compartment defects including rectal prolapse and rectal intussusception are often associated with middle and anterior compartment prolapse and require a multicompartment approach to treatment. In recent years, ventral rectopexy, with or without sacrocolpopexy for combined middle compartment prolapse, has emerged as a safe and effective method of treatment for rectal prolapse. In this article, we aim to review the etiology of rectal prolapse and intussusception, describe the indications and workup for surgery, discuss technical aspects of ventral rectopexy alone and in combination with sacrocolpopexy, review potential surgical complications, and describe the reported outcomes of the surgery.
Rhinophyma: Combined Surgical Treatment and Quality of Life
Authors: Daoud Mahmoud , Ullas Gautham , Kumar Rakesh , Raghavan Ullas 
Published: September 2020

AbstractRhinophyma is a progressive and disfiguring thickening of the nasal skin. It is typically found in middle-aged or elderly Caucasian males. The exact cause of the disease is unknown. There is excessive formation of scar-like tissue and hyperplasia of the sebaceous glands. This article will demonstrate our experience of treating rhinophyma using a combined surgical approach and propose a novel classification system. This is a retrospective analysis of cases operated by a single surgeon over 9 years using the Glasgow Benefit Inventory (GBI) tool. Thirty-three patients were identified. Twenty-nine patients had three techniques used in one sitting, two patients had two techniques used, and two further patients had one technique used. Total GBI showed a +50.99 result following surgery. Rhinophyma treatments can benefit patients as demonstrated by the GBI outcome. This can improve the patients' quality of life. The use of more than one technique in the same sitting potentially improves the outcome. Our classification system helps categorize the disease better as well as choosing the treatment and comparing disease and treatment. The Level of Evidence for the study is 4.
Evidence for the Efficacy of Ultra-High Diluted Homoeopathic Medicines in the Management of Influenza-Like Illness: A Narrative Review
Authors: Mukherjee Anupam , Sinha Neeti , Dey Joy Kumar , Jadhav Arun Bhargav 
Published: September 2020

Abstract
Introduction In view of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the rise in cases of influenza-like illness (ILI), there is urgent need of developing and scientifically establishing treatment strategies. Homoeopathy has been used effectively in various pandemics for a long-time showing potential of combating such outbreaks effectively. This study aims at evaluating the methodological quality of the clinical trials conducted with a motive of assessing the efficacy of homoeopathy in management of ILI.
Methods The randomised clinical research manuscripts from various databases were included for the narrative review. In this study, the Jadad scale was applied as an assessment tool with the criteria of randomisation, blinding and withdrawals to evaluate the methodological quality of the selected randomised controlled trials.
Results The seven randomised controlled trials fulfilling the inclusion criteria evaluated on Jadad scale lay between the ranges of 2 to 5 with a mean score of 3.71 implicating the efficacy of homoeopathy in ILI. Six studies showed significant role of homoeopathy in the faster recovery of ILI symptoms. One trial, however, reported no noticeable difference in intergroup (treatment and placebo group) improvement but distinct intragroup comparison was observed.
Conclusion It was concluded from this narrative review that homoeopathy has significant role in faster recovery of ILI symptoms in comparison to placebo group, and it can be employed as a potential treatment strategy in the recurrent pandemics of ILI and the currently prevailing coronavirus disease 2019 (COVID-19) crisis. It is suggested that more clinical trials with standard methodology should be conducted in this regard.
Decompressive Craniectomy for Traumatic Brain Injury: In-hospital Mortality-Associated Factors
Authors: Celi Fernando , Saal-Zapata Giancarlo 
Published: September 2020

Abstract

Objective Determine predictors of in-hospital mortality in patients with severe traumatic brain injury (TBI) who underwent decompressive craniectomy.

Materials and Methods This retrospective study reviewed consecutive patients who underwent a decompressive craniectomy between March 2017 and March 2020 at our institution, and analyzed clinical characteristics, brain tomographic images, surgical details and morbimortality associated with this procedure.

Results Thirty-three (30 unilateral and 3 bifrontal) decompressive craniectomies were performed, of which 27 patients were male (81.8%). The mean age was 52.18 years, the mean Glasgow coma scale (GCS) score at admission was 9, and 24 patients had anisocoria (72.7%). Falls were the principal cause of the trauma (51.5%), the mean anterior–posterior diameter (APD) of the bone flap in unilateral cases was 106.81 mm (standard deviation [SD] 20.42) and 16 patients (53.3%) underwent a right-sided hemicraniectomy. The temporal bone enlargement was done in 20 cases (66.7%), the mean time of surgery was 2 hours and 27 minutes, the skull flap was preserved in the subcutaneous layer in 29 cases (87.8%), the mean of blood loss was 636.36 mL,and in-hospital mortality was 12%. Univariate analysis found differences between the APD diameter (120.3 mm vs. 85.3 mm; p = 0.003) and the presence of midline shift > 5 mm (p = 0.033).

Conclusion The size of the skull flap and the presence of midline shift > 5 mm were predictors of mortality. In the absence of intercranial pressure (ICP) monitoring, clinical and radiological criteria are mandatory to perform a decompressive craniectomy.
Asymmetrical cross-language phonetic interaction
Authors: Schwartz Geoffrey 
Published: September 2020

AbstractTwo acoustic studies were carried out with L1 Polish learners of English. One study examined L1 phonetic drift, comparing learners of L2 English who were undergoing intensive L2 phonetic training with quasi-monolingual Polish speakers. The other study looked at L2 acquisition, comparing learners at two different levels of proficiency. Unlike most previous studies of Polish-English bilinguals, VOT data of both voiced and voiceless consonants were analyzed. In both experiments, an asymmetry was observed by which voiced stops were more susceptible to cross-language phonetic influence (CLI) than voiceless stops. These results build on evidence of a similar asymmetry observed in a number of other L1–L2 pairings. Predictions of competing phonological models are evaluated with regard to equivalence classification and phonetic CLI. It is shown that both traditional approaches to the phonological representation of voice contrasts fail to predict the observed asymmetry. An alternative theory, which predicts the asymmetry, is discussed.
The future of Extracellular Vesicles as Theranostics – an ISEV meeting report
Authors: Soekmadji Carolina , Li Bo , Huang Yiyao , Wang Haifang , An Taixue , Liu Chunchen , Pan Weilun , Chen Jing , Cheung Lesley , Falcon‐Perez Juan Manuel , Gho Yong Song , Holthofer Harry B. , Le Minh T. N. , Marcilla Antonio , O'Driscoll Lorraine , Shekari Faezeh , Shen Tang Long , Torrecilhas Ana Claudia , Yan Xiaomei , Yang Fuquan , Yin Hang , Xiao Yu , Zhao Zezhou , Zou Xue , Wang Qian , Zheng Lei 
Published: September 2020

ABSTRACTThe utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on “EVs in Clinical Theranostic”. Here, we report the conclusions of roundtable discussions on the current advancement in the analysis technologies and we provide some guidelines to researchers in the field to consider the use of EVs in clinical application. The main challenges and the requirements for EV separation and characterization strategies, quality control and clinical investigation were discussed to promote the application of EVs in future clinical studies.
Testing generalized Einstein–Cartan–Kibble–Sciama gravity using weak deflection angle and shadow cast
Authors: Övgün Ali , Sakallı İzzet 
Published: September 2020

Abstract
In this paper, we use a new asymptotically flat and spherically symmetric solution in the generalized Einstein–Cartan–Kibble–Sciama (ECKS) theory of gravity to study the weak gravitational lensing and its shadow cast. To this end, we first compute the weak deflection angle of generalized ECKS black hole using the Gauss–Bonnet theorem in plasma medium and in vacuum. Next by using the Newman–Janis algorithm without complexification, we derive the rotating generalized ECKS black hole and in the sequel study its shadow. Then, we discuss the effects of the ECKS parameter on the weak deflection angle and shadow of the black hole. In short, the goal of this paper is to give contribution to the ECKS theory and look for evidences to understand how the ECKS parameter effects the gravitational lensing. Hence, we show that the weak deflection of black hole is increased with the increase of the ECKS parameter.
Understanding partonic energy loss from measured light charged particles and jets in PbPb collisions at LHC energies
Authors: Shukla Prashant , Saraswat Kapil 
Published: September 2020

Abstract
We perform a comprehensive study of partonic energy loss reflected in the nuclear modification factors of charged particles and jets measured in PbPb collisions at

s

NN

= 2.76 and 5.02 TeV in wide transverse momentum (p
T) and centrality range. The p
T distributions in pp collisions are fitted with a modified power law and the nuclear modification factor in PbPb collisions can be obtained using effective shift (Δp
T) in the spectrum measured at different centralities. Driven by physics consideration, the functional form of energy loss given by Δp
T can be assumed as power law with different power indices in three different p
T regions. The power indices and the boundaries of three p
T regions are obtained by fitting the measured nuclear modification factor as a function of p
T in all collision centralities simultaneously. The energy loss in different collisions centralities are described in terms of fractional power of number of participants. It is demanded that the power law functions in three p
T regions and their derivatives are continuous at the p
T boundaries. The Δp
T for light charged particles is found to increase linearly with p
T in low p
T region below ∼5–6 GeV c−1 and approaches a constant value in high p
T region above ∼22–29 GeV c−1 with an intermediate power law connecting the two regions. The method is also used for jets and it is found that for jets, the Δp
T increases approximately linearly even at very high p
T.
Spin–phonon coupling and thermodynamic behaviour in YCrO3 and LaCrO3: inelastic neutron scattering and lattice dynamics
Authors: Gupta Mayanak K , Mittal Ranjan , Mishra Sanjay K , Goel Prabhatasree , Singh Baltej , Rols Stephane , Chaplot Samrath L 
Published: September 2020

Abstract
We report detailed temperature-dependent inelastic neutron scattering and ab initio lattice dynamics investigation of magnetic perovskites YCrO3 and LaCrO3. The magnetic neutron scattering from the Cr ions exhibits significant changes with temperature and dominates at low momentum transfer regime. Ab initio calculations performed including magnetic interactions show that the effect of magnetic interactions is very significant on the low- as well as high-energy phonon modes. We have also shown that the inelastic neutron spectrum of YCrO3 mimics the magnon spectrum from a G-type antiferromagnetic system, which is consistent with previously reported magnetic structure in the compound. The pressure-dependent ab initio lattice dynamics calculations are used to calculate the anisotropic thermal expansion behaviour in orthorhombic YCrO3, which is in excellent agreement with the available experimental data in the paramagnetic phase. We identify that the low energy anharmonic phonon modes involving Y vibrations contribute maximum to the thermal expansion behaviour.
Controllably facile design of electrophoretic-induced film-forming of nano tungsten oxide (VI) and their anti-wetting functionalization
Authors: Guo Xiaogang , Liang Taotao , Yuan Binfang , Wang Jing , Sun Qi 
Published: September 2020

AbstractThere is keen interest for designing promising tungsten oxide (VI, WO3) films or coatings due to their wide applications in fields of energy, engineering, etc. Thus, this paper firstly introduce a novel convenient method of electrophoretic assembly technique (EAT) in an optimal stable suspension of isopropyl alcohol, PEG-1000 and polyethyleneimine for designing the promising anti-wetting functional WO3(VI) films with relative rough structures and uniform distribution in mild conditions. The product possess a high crystallinity and pureness by x-ray powder diffraction analysis. The EAT dynamic behaviours of WO3(VI) nanoparticles are investigated in detail. Moreover, obtained films shows excellent anti-wetting properties after suface modification, and the hydrophobic studies results demonstrate that product have a high static water CA of approximate 169° and keep nearly stable even after ultralong exposure time (360 d), and show outstanding properties of anti-soaking, impacting-proof, and moisture resistance even in high relative humidity (90%). These breakthroughs will substantially push forward the convenient processing of other anti-wetting functional coatings with wide potential applications.
Development of a tomographic reconstruction method for axisymmetric Dα emission profiles in the ITER plasma boundary
Authors: Neverov Vladislav S , Khusnutdinov Radmir I , Alekseev Andrey G , Carr Matthew , De Bock Maarten , Kukushkin Alexander B , Lovell Jack , Meakins Alex , Pitts Richard , Polevoi Alexei R , Veshchev Evgeny 
Published: September 2020

Abstract
A tomographic method for reconstructing the axially symmetric Dα emission profile in the ITER scrape-off layer and divertor from Dα intensity measurements in the fields of view (FoV) of Vis/IR TV and Divertor Impurity Monitor diagnostics is under development. The method takes into account the strong background signal due to stray light from divertor produced by reflections from the metal wall of the vacuum chamber. The method allows to filter out the reflections in Dα signals measured in the main chamber. The accuracy of this method is tested within the framework of a synthetic diagnostic, which uses the Raysect and Cherab numerical codes for ray-tracing simulations. The Dα emission profiles, simulated with the SOLPS and OEDGE codes, are used as synthetic experimental data. Uncertainty in light reflection properties of the first wall (FW) is the major factor affecting the accuracy of the Dα emission reconstruction. The dependence on the uncertainty in the FW surface roughness and on the ratio of diffusive to specular reflection of the error in recovering useful Dα signals (the direct light without reflections) in the FoV of the ITER main chamber H-alpha and Visible Spectroscopy Diagnostic is obtained.
Identification and characterization of topological structures of turbulence in magnetic confined plasmas
Authors: García L , Carreras B A 
Published: September 2020

Abstract
Transport in turbulent magnetic plasmas is closely related to the flow topological structures. These are mainly filamentary vortices linked to the magnetic filed lines and zonal flows generated from turbulence. Their identification in the experiments is not yet clear. In this work, resistive magneto-hydrodynamics simulations are used to generate turbulent flows in a plasma. The topological structures obtained from the simulations are analyzed using three different techniques: long-distance correlations, transfer of entropy and intermittence. The combination of the results using these techniques allows us to identify and characterize vortex structures and zonal flows.
A novel magnetorheological elastomer-based adaptive tuned vibration absorber: design, analysis and experimental characterization
Authors: Rasooli Armin , Sedaghati Ramin , Hemmatian Masoud 
Published: September 2020

Abstract
The present study aims at the development of a novel semi-active adaptive tuned vibration absorber (SATVA) capable of tuning its natural frequency adaptively in low frequency range. The absorber consists of a multilayer sandwich beam featuring magnetorheological elastomer (MRE) and integrated U-shaped electromagnets which are attached at the top and bottom layers of the sandwich beam. Electromagnets are designed to provide the required magnetic field to alter the stiffness of the MRE layers while also acting as the active mass of the absorber. Based on the characterization of the shear and loss modulus of the fabricated MRE samples, the finite element (FE) model of the proposed SATVA has been developed to analyze the absorber to meet the design requirements and also to evaluate its dynamic performance. The proposed SATVA is then fabricated and experimental set-ups are designed to validate the electromagnet and FE models. The frequency response function of the proposed SATVA is then investigated under different levels of the applied current to the electromagnets. It has been shown that good agreement exists between simulation and FE results. A frequency-shift of approximately 9% was achieved while maintaining a reasonable factor of safety for material constraints. Finally, using the validated FE mode, a parametric study has been conducted to investigate the effect of different design parameters.
Mesothelial Cysts
Authors: Karpathiou Georgia , Casteillo Francois , Dridi Maroa , Peoc’h Michel 
Published: September 2020

Abstract

Objectives
Peritoneal mesothelial cysts have been reported under various terms, including benign cystic mesothelioma, usually in the form of case reports/series, whereas extraperitoneal cases are rarely reported. Our objective was to report the detailed characteristics of cystic lesions of the serosal cavities.

Methods
We retrospectively examined the clinicopathologic findings of a series of mesothelial cystic lesions (n = 79).

Results
Most cases (n = 68, 86%) concerned the peritoneum, whereas 11 (14%) concerned the pericardium. No pleural cases were found. A total of 51 (64.5%) lesions were solitary, whereas 28 (35.5%) were multiple. Peritoneal lesions harbored a plump eosinophilic mesothelium and a loose connective stroma, whereas pericardial lesions showed a cuboidal/flattened mesothelium, collagenous stroma, intense inflammation, and other tissue types, like adipose and muscle tissue. Solitary peritoneal lesions are usually extrapelvic and found in older patients incidentally during other surgeries, whereas multiple lesions are found in younger patients and usually in the pelvis. The lesions show a benign clinical course with rare recurrences but no malignant transformation.

Conclusions
Most mesothelial cysts are peritoneal and rarely pericardial. Peritoneal cysts differ from pericardial cysts. Peritoneal solitary lesions differ from multiple lesions, also suggesting their pathogenetic differences.