bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVALUASI KINERJA SAHAM BERTANGGUNGJAWAB SOSIAL (STUDI PADA SAHAM-SAHAM YANG MASUK PERHITUNGAN INDEKS SRI-KEHATI)
Authors: Lakaba Angriana , Robiyanto Robiyanto 
Published: April 2020

Severals studies on the performance of stocks, especially those that examine the constituent of social responsibility in the Indonesia Stock Exchange, in general still focus on the performance assessment of the SRI-Kehati Index, have not specifically reviewed the performance of the constituent stocks of the SRI-Kehati Index. Therefore, this study specifically examines constituent stocks of the SRI-Kehati Index. The study period used is 2009 to 2017. The sample in this study are 13 stocks that consistently enter into the calculation of SRI-Kehati Index during the study period. The stock performance assessment will be performed using Sharpe Index, Jensen Alpha, Treynor Ratio, Sortino Ratio, Information Ratio. Overall, the consistent stocks listed in the SRI-Kehati Index may not necessarily indicate good stock performance. From 13 stocks, some have negative results which can be classified as non-performing stock.
Berbagai penelitian terkait kinerja saham-saham bertanggungjawab sosial di Bursa Efek Indonesia secara umum masih berfokus pada penilaian kinerja Indeks SRI-Kehati, namun belum secara khusus mengkaji kinerja saham-saham pembentuk Indeks SRI-Kehati. Oleh sebab itu penelitian ini secara khusus mengkaji saham-saham pembentuk Indeks SRI-Kehati. Periode penelitian yang digunakan adalah periode tahun 2009 hingga tahun 2017. Sampel dalam penelitian ini adalah 13 saham yang secara konsisten masuk ke dalam perhitungan Indeks SRI-Kehati selama periode penelitian. Penilaian kinerja saham akan dilakukan dengan menggunakan Indeks Sharpe, Jensen Alpha, Rasio Treynor, Rasio Sortino, Information Ratio. Secara keseluruhan, saham-saham yang konsisten terdaftar dalam Indeks SRI-Kehati belum semua menunjukkan kinerja saham yang baik. Dari 13 saham yang diteliti masih ada beberapa saham dengan hasil negatif yang berarti masih mempunyai kinerja saham yang buruk.
A catalogue of Danian gastropods from the Baunekule facies, Faxe Formation, Denmark
Authors: Lauridsen Bodil W. , Ingemann Schnetler Kai 
Published: April 2020

This catalogue of 194 gastropod taxa is based on the collection of Danian gastropods from the Baunekule facies, Faxe Formation in eastern Denmark. The gastropod fauna is extremely rich and well preserved. Most of the gastropods (106 species) are referred to genus level only, 9 morphotypes to even higher taxonomical levels and 79 gastropods are referred to species level. The gastropods are classified following Bouchet & Rocroi (2005) as 4 different clades: Vetigastropoda (represented by 26 species and 10 superfamilies), Caenogastropoda (represented by 142 species and 17 superfamilies), Heterobranchia (represented by 23 species and 5 superfamilies) and Opisthobranchia (represented by 1 species and 1 superfamily). The new species Zaclys? nuetzeli n. sp. is introduced.
The Faxe Formation is recognised as a cold-water coral ecosystem with interfingering smaller bryozoan mounds. The Baunekule facies is found in the upper part of the coral mound complex of the Faxe Formation, where it forms isolated lensoidal bodies in the flanks of some of the coral mounds. It is characterised by a high diversity invertebrate fauna that occurs in weakly consolidated coraldominated floatstone to rudstone. The diagenesis of the Baunekule facies is of special significance because a high proportion of the originally aragonite-shelled fauna is preserved by recrystallization to calcite during early burial diagenesis. Most of the gastropods are not known from other parts of the Faxe Fm. The fauna is very important for comparative evolutionary studies of fossil and modern gastropods on cold-water coral mounds. Many of the genera have not previously been recorded from Danian strata. None of the gastropod species found in the Baunekule facies are known for certain to range below the Cretaceous–Palaeogene boundary. The fauna is comparable to gastropods found on modern cold-water coral mounds in the North Atlantic.
The gastropod fauna from the Baunekule facies is characterised by a very high diversity of rather small millimetre-sized gastropods with a preference for hard substrates; 63.9% of the taxa belong to the browsing carnivore trophic group, feeding mainly on sedentary animals. Surprisingly, the fauna contains some common occurrences of typically warm-water species. The fauna consists mostly of Cenozoic genera and up to 87% of the species may be endemic to the cold-water coral ecosystem of the Faxe Formation. The diverse and rather unusual gastropod fauna from the Baunekule facies is undoubtedly linked to the evolution of cold-water coral ecosystems.
SELECTION-GENETIC CHARACTERISTICS OF RABBITS POLTAVSKA SILVER BREED BY POLYMORPHISM OF PROGESTERONE RECEPTOR GENE
Authors: Shevchenko Eugene , Honchar Oleksiy 
Published: April 2020

Genetic certification of the Poltavska silver rabbits by the progesterone receptor gene was carried out by amplification of the corresponding sections of genomic DNA in the Polymerase Chain Reaction (PCR). As a result of PCR analysis it was found that the discrete DNA bands of rabbits were intensive hybridization spectra and characterized by different numbers, locations, and intensities of detected fragments. Based on the results of genotyping of Poltavska silver rabbits the following data on their genetic structure were obtained for gene polymorphism G2464A. In actual distribution of genotypes number of homozygous animals with the G gene was 18.3% (11 animals), number of homozygotes for A allele was almost twice as large (31.7%). The Wright fixation index for both polymorphic variants was negative which demonstrates the advantage of heterozygotes in population for tested genes. It was established that high values of multiple fertility rate in three aprons were found in rabbits with the GG genotype, and the lowest - with the AA genotype.
In general there was a tendency to increase fertility by an average of 12% in three spouts for the “desired genotype” GG compared to animals that had genotypes AA and AG (p<0.05). Analysis of variation in milk yield of rabbits genotypes by polymorphic variants of progesterone receptor showed that this indicator was higher in homozygous animals AA, and the lowest - in heterozygotes AG. Moreover, rabbits with GG genotype were 3% inferior to them (the difference is not significant). According to the results of one-way analysis of variance, the influence of the rabbit genotype on the progesterone receptor gene on their milk production was found but no statistically significant difference between groups of animals with different genotypes. According to the data obtained it can be argued that the genotype of Poltavska Silver female rabbits in progesterone receptor gene has statistically significant effect on the manifestation of multiple pregnancy which can also be used in breeding.
The NANOGrav 11 yr Data Set: Constraints on Planetary Masses Around 45 Millisecond Pulsars
Authors: Behrens E. A. , Ransom S. M. , Madison D. R. , Arzoumanian Z. , Crowter K. , DeCesar M. E. , Demorest P. B. , Dolch T. , Ellis J. A. , Ferdman R. D. , Ferrara E. C. , Fonseca E. , Gentile P. A. , Jones G. , Jones M. L. , Lam M. T. , Levin L. , Lorimer D. R. , Lynch R. S. , McLaughlin M. A. , Ng C. , Nice D. J. , Pennucci T. T. , Perera B. B. P. , Ray P. S. , Spiewak R. , Stairs I. H. , Stovall K. , Swiggum J. K. , Zhu W. W. 
Published: April 2020

Abstract
We search for extrasolar planets around millisecond pulsars using pulsar timing data and seek to determine the minimum detectable planetary masses as a function of orbital period. Using the 11 yr data set from the North American Nanohertz Observatory for Gravitational Waves (NANOGrav), we look for variations from our models of pulse arrival times due to the presence of exoplanets. No planets are detected around the millisecond pulsars in the NANOGrav 11 yr data set, but taking into consideration the noise levels of each pulsar and the sampling rate of our observations, we develop limits that show we are sensitive to planetary masses as low as that of the moon. We analyzed potential planet periods, P, in the range 7 days < P < 2000 days, with somewhat smaller ranges for some binary pulsars. The planetary-mass limit for our median-sensitivity pulsar within this period range is

.
Spherical Aberration Customization to Extend the Depth of Focus With a Clinical Adaptive Optics Visual Simulator
Authors: Hervella Lucía , Villegas Eloy A. , Robles Consuelo , Artal Pablo 
Published: April 2020

PURPOSE:
To evaluate the use of the VAO adaptive optics visual simulator (Voptica SL, Murcia, Spain) for customization of spherical aberration to increase depth of focus.

METHODS:
Through-focus visual acuity with both high- and low-contrast letters from +1.00 to −3.00 diopters (D) was measured in 17 dilated eyes with three different induced amounts of spherical aberration for a 4.5-mm pupil diameter: control (0 µm), −0.15 µm, and −0.30 µm.

RESULTS:
The defocus curves followed the same behavior with both values of contrast, but the visual acuity was 0.2 logMAR lower with low contrast. The mean values of high-contrast logMAR visual acuity at far, intermediate (67 cm), and near (40 cm) were −0.10, 0.11, and 0.37 for control, 0.04, 0.00, and 0.15 for −0.15 µm, and 0.23, 0.00, and 0.06 for −0.30 µm conditions. The 95% confidence interval ranged from ±0.14 to ±0.45 logMAR and the middle 50% of the distribution was approximately 0.2 logMAR.

CONCLUSIONS:
Negative values of spherical aberration extend the depth of focus in different ways depending on each patient. The VAO is a new instrument that allows the visual customization of spherical aberration to enhance depth of focus.

[
J Refract Surg
. 2020;36(4):223–229.]
Association Between Keratoconus and Thyroid Gland Dysfunction: A Cross-Sectional Case–Control Study
Authors: El-Massry Ahmed , Doheim Mohamed Fahmy , Iqbal Mohammed , Fawzy Omar , Said Omar M. , Yousif Mohamed O. , Badawi Amani E. , Tawfik Ahmed , Abousamra Amir 
Published: April 2020

PURPOSE:
To examine the clinical association between thyroid gland dysfunction and keratoconus.

METHODS:
This was a cross-sectional case–control study conducted between May 2018 and July 2019. After performing Pentacam (Oculus Optikgeräte GmbH, Wetzlar, Germany) examination, flat, steep, and maximum simulated keratometric readings were recorded for each patient. Serum concentrations of free triiodothyronine, free thyroxine, and thyroid-stimulating hormone were measured. Further examinations by an endocrinologist were indicated for patients with positive laboratory results to confirm thyroid gland dysfunction.

RESULTS:

One hundred eighty-seven patients with bilateral keratoconus and 187 sex- and age-matched healthy controls without keratoconus were analyzed. Mean age was 26.4 ± 8.2 years for the patients with keratoconus and 27.1 ± 9.4 years for the control patients, with no significant difference. The results showed that thyroid gland dysfunction prevalence was 10 of 187 patients with keratoconus (5.3%) and 2 of 187 control patients (1.1%), and the difference was statistically significant (
P
= .036). For the patients with keratoconus and thyroid gland dysfunction, 8 were women and 2 were men. Additionally, 6 patients (2 men and 4 women) had hyperthyrosis and 4 women had hypothyrosis. For controls, the two patients had hypothyrosis.

CONCLUSIONS:
This study showed that there is a possible association between keratoconus and thyroid gland dysfunction, but more studies are needed to build upon these results.

[
J Refract Surg
. 2020;36(4):253–257.]
Interaction of Monochromatic and Chromatic Aberrations in Pseudophakic Patients
Authors: Marcos Susana , Romero Mercedes , Benedí-García Clara , González-Ramos Ana , Vinas Maria , Alejandre Nicolás , Jiménez-Alfaro Ignacio 
Published: April 2020

PURPOSE:
To measure monochromatic aberrations at various wavelengths in eyes implanted with the Clareon monofocal aspheric intraocular lens (IOL) (Alcon Laboratories, Inc., Fort Worth, TX). The authors estimated longitudinal chromatic aberration (LCA), modulation transfer functions (MTFs), and the impact of interactions between chromatic and monochromatic aberrations on retinal image quality.

METHODS:
Ten patients (age: 68.4 ± 3.21 years) were measured in two experiments: (1) Hartmann-Shack wave aberrations at five visible wavelengths (480 to 700 nm) and (2) best subjective focus at each wavelength. Objective and psychophysical LCAs were obtained from the Zernike defocus and psychophysical best focus, respectively. MTFs were calculated for the closest wavelengths to the peak sensitivity of the three cone classes (S [480 nm], M [555 nm], and L [564 nm]) using the measured aberrations and chromatic difference of focus. The degradation produced by LCA was estimated as the visual Strehl ratio for green divided by the visual Strehl ratio for blue and red.

RESULTS:

The root mean square for higher order aberrations (HOAs) ranged from 0.0622 to 0.2084 µm (700 nm, 4.3-mm pupil). Monochromatic visual Strehl ratio was above 0.35 in all patients. LCA was 1.23 ± 0.05 diopters (D) (psychophysical) and 0.90 ± 0.11 D (objective). Visual Strehl ratio decreased by a factor ranging from 1.38 to 3.82 on chromatic defocus from green to blue. There was a significant correlation between native visual Strehl ratio and the degradation produced by LCA (ie, visual Strehl
555
/visual Strehl
480
).

CONCLUSIONS:
The Clareon IOL compensates for spherical aberration, with postoperative wave aberrations dominated by astigmatism and other HOAs, being highly subject-dependent. The impact of LCA in blue is largely dependent on the magnitude of monochromatic aberrations.

[
J Refract Surg
. 2020;36(4):230–238.]
Proteomic variations after short-term heat shock treatment reveal differentially expressed proteins involved in early microspore embryogenesis in cabbage (Brassica oleracea)
Authors: Su Henan , Chen Guo , Yang Limei , Zhang Yangyong , Wang Yong , Fang Zhiyuan , Lv Honghao 
Published: April 2020

Microspore embryogenesis (ME), a widely used haploid breeding method that can considerably shorten the breeding cycle, provides an efficient mean of cultivating many important Brassica crops, such as cabbage, Chinese cabbage, and oilseed rape. For cabbage, in many cases, short-term heat shock treatment can strongly increase the embryogenesis rate, however, the underlying mechanism of this effect has not been elucidated. In this study, we compared the proteomics of isolated microspores with samples pretreated at 32 °C for 24 h and 25 °C for 24 h using two cabbage accessions (Zhonggan 628 and 87–534) showing highly different embryogenic rates. The embryo yield was 19.7 embryos/bud in Zhonggan 628 after 32 °C treatment, while no embryoid was observed in Zhonggan 628 after 25 °C treatment as well as in 87–534 at both temperatures. We identified a total of 363 and 282 differentially expressed proteins (DEPs) for Zhonggan 628 and 87–534 via a label-free proteomics technology. There were 97 DEPs specifically identified only in Zhonggan 628 but not in 87–534 after 32 °C heat-shock treatment that may be related to heat shock-induced embryogenesis in vitro culture. These DEPs were primarily enriched in carbon metabolic process, protein synthesis and degradation process, and signal transduction. Based on protein-protein interaction and pathway enrichment analyses, we proposed that SGT1 homolog A and B(SGT1), heat shock 70 kDa protein 5 (HSP70), cell division control protein 48 homolog A (CDC48) and fatty acyl-CoA reductase (FAR) might play important roles in microspore embryogenesis. This proteomic study may contribute to our molecular understanding of cabbage microspore embryogenesis and help to build a high-efficiency haploid breeding system.
Letramento crítico e ensino intercultural como práticas relevantes em contexto de internacionalização: foco no planejamento de um curso de alemão como LE
Authors: Marques Lívia dos Santos , Rozenfeld Cibele Cecilio de Faria 
Published: April 2020

Diante de um cenário de internacionalização nas universidades, é importante que a comunidade acadêmica esteja preparada para o confronto com a diversidade cultural, e para tanto, defendemos que o letramento crítico e o ensino de línguas intercultural trazem uma nova perspectiva sobre a noção de língua, cultura e a educação. Essa nova visão pode transformar a maneira como o professor planeja aulas ou cursos de língua estrangeira (LE). Assim, este artigo tem como objetivo refletir teoricamente sobre o planejamento de cursos a partir das premissas do letramento crítico e ensino intercultural, e analisar o planejamento de curso de língua alemã realizado com base nessas teorias de ensino. Para tanto, apoiaremo-nos em autores que tratam sobre o planejamento de cursos de LE (DUBIN, OLSCHTAIN, 1986; ALMEIDA FILHO, 1997; RICHARDS, 2001; ALMEIDA FILHO, 2012), o letramento crítico (HAMMOND, MACKEN-HORARIK, 1999; SOUZA, 2011; JORDÃO, 2013; ROZENFELD, 2016) e o ensino de línguas intercultural (BYRAM, 1997; HOUSE, 2007; KRAMSCH, 2009; LIDDICOAT, 2011). A partir do estudo dos autores citados, realizamos uma pesquisa qualitativa e exploratória, com foco na análise do planejamento de um minicurso de seis horas, para alunos universitários de Letras, que consistiu na exibição e discussão da minissérie alemã Unsere Mütter Unsere Väter. Por meio da análise, foi possível notar que o planejamento seguiu os princípios do ensino intercultural estabelecidos no modelo de Byram (1997), e pretendeu alcançar os principais objetivos do letramento crítico, preparando o aluno, assim, para o contexto de internacionalização. Concluiu-se que, além de estar coerente com ambas as teorias, é necessário que o professor repense sua prática e execute projetos que estimulem o aluno a agir em favor da mudança social e cidadania.
FeOOH/rGO/BiVO4 Photoanode for Highly Enhanced Photoelectrochemical Water Splitting Performance
Authors: Zeng Guihua , Hou Liqiong , Zhang Jialing , Zhu Jiaqian , Yu Xiang , Fu Xionghui , Zhu Yi , Zhang Yuanming 
Published: April 2020

AbstractBismuth vanadate (BiVO4) is regarded as a potential material in photoelectrochemical (PEC) water splitting, but the photocurrent of BiVO4 photoanode is much lower than its theoretical value for the high recombination of photo‐induced charges and slow water oxidation kinetics. Here, we constructed a FeOOH/rGO/BiVO4 photoanode, in which rGO could enhance the photogenerated electron‐hole separation efficiency by transporting holes and the FeOOH could greatly accelerate the water oxidation kinetics. This novel photoanode displayed excellent PEC performance with the photocurrent density of 3.25 mA cm−2 at 1.23 V vs. RHE, 3.28 times higher than BiVO4 photoanode (0.99 mA cm−2), and long‐term stability with the Faraday efficiency of ∼98 % for 3 hours, demonstrating its great potential for PEC water splitting. The photoanode also provided a novel insight into the role of rGO to transport holes rather than electrons in improving the carrier separation efficiency.
Preanalytic variables in quality and quantity of nucleic acids extracted from FNA specimens of thyroid gland nodules collected in CytoLyt: Cellularity and storage time
Authors: Heymann Jonas J. , Yoxtheimer Lorene M. , Park Hyeon Jin , Fernandez Evan M. , Facey Kirk E. , Alperstein Susan A. , Tran Hung V. , Baek Inji , Scognamiglio Theresa , Rennert Hanna , Siddiqui Momin T. , Song Wei 
Published: April 2020

BackgroundMorphologic and genetic analysis of thyroid nodules may be performed from a single vial. Preanalytic variables that affect nucleic acid extracted from a single vial are evaluated.MethodsThyroid fine‐needle aspiration (FNA) specimens collected in CytoLyt were evaluated. A ThinPrep slide was prepared. Extracted nucleic acids were analyzed using Oncomine Comprehensive Panel, version 2, after Ion AmpliSeq library preparation. A pathologist and a cytotechnologist enumerated specimen cellularity.ResultsFifty‐six samples were collected from 55 nodules in 53 patients. Bethesda category correlated with cellularity (P = .01), and storage time (median, 43 days; range, 7‐77 days) was longer for specimens in categories II and III than for those in categories IV and VI (P = .01). The mean specimen DNA concentration was 4.5 ng/µL (range, 0‐23.8 ng/µL), and 25 (45%) had concentrations >3.3 ng/µL. The mean specimen RNA concentration was 4.8 ng/µL (range, 0‐42.4 ng/µL), and 31 (55%) had concentrations >1.4 ng/µL. Nucleic acid quantity increased with epithelial cellularity. Storage time weakly correlated with the quantity of extracted DNA, independent of cellularity, but not extracted RNA. Greater proportions of cell‐free DNA and lesser proportions of long, intact RNA fragments were extracted from a subset of samples with longer storage time. Among 15 single nucleotide variants, the median mutant allelic fraction was 15.1%. One false‐negative result was identified. Five specimens subsequently determined to harbor a genetic alteration failed quality metrics.ConclusionsCellularity and storage time affect the quantity and quality of nucleic acid extracted from thyroid FNA specimens collected in CytoLyt. Further investigation will serve to quantify the magnitude of such effects and to elucidate other contributing factors.
Possible associations between plasma fibroblast growth factor 21 levels and cognition in bipolar disorder
Authors: Omileke Favour , Ishiwata Sayuri , Matsuo Junko , Yoshida Fuyuko , Hidese Shinsuke , Hattori Kotaro , Kunugi Hiroshi 
Published: April 2020

AbstractBipolar disorder (BD) is a mental disorder characterized by extreme changes in mood polarity. It is also characterized by cognitive and metabolic dysfunctions. Fibroblast growth factor 21 (FGF21) is an endocrine protein that has a multifaceted function such as glucose and lipid regulation in the periphery, and neuroprotection and induction of synaptic plasticity in the central nervous system. Previous studies reported inconsistent results concerning peripheral FGF21 levels in patients with BD. In this study, we compared plasma FGF21 levels between 26 patients with BD and 51 healthy controls using a human FGF21 ELISA Kit. There was no significant difference in plasma FGF21 levels between the patients and controls. We found significant positive correlations between plasma FGF21 levels and some cognitive parameters (word association and motor speed). If our results are replicated that higher peripheral FGF21 may be associated with better cognitive performance in patients with BD.
Apathy symptoms induced by low‐dose venlafaxine: Two cases
Authors: Sato Shinji , Sodeyama Noriko , Matsuzaki Asaki , Shiratori Yuki 
Published: April 2020

AbstractRecent guidelines regarding pharmacological interventions for major depressive disorder (MDD) recommend first using serotonin (5HT) selective reuptake inhibitors (SSRIs) or 5HT and norepinephrine (NE) reuptake inhibitors (SNRIs). Although SSRIs and SNRIs are effective and well‐tolerated, apathy occurs as an adverse effect in some SSRIs‐treated patients. Because apathy would be associated with the 5HT pathway, if a patient exhibits apathy symptoms under SSRIs treatment, a clinical strategy has been to change the SSRIs to treatment with an SNRIs. Here, I report two cases in which low‐dose venlafaxine, an SNRIs, induced apathy symptoms.