bluuebunny/crossref_metadata_2025_split huggingface dataset:
Defender and Expositor of the Bergen Methods of Synoptic Analysis: Significance, History, and Translation of Bergeron’s (1928) “Three-Dimensionally Combining Synoptic Analysis”
Authors: Schultz David M. , Volkert Hans , Antonescu Bogdan , Davies Huw C. 
Published: June 2020

AbstractTor Bergeron was a key member of the Bergen School of Meteorology that developed some of the most influential contributions to synoptic analysis in the twentieth century: airmass analysis, polar-front theory, and the Norwegian cyclone model. However, the eventual success of these so-called Bergen methods of synoptic analysis was not guaranteed. Concerns and criticisms of the methods—in part from the lack of referencing to prior studies, overly simplified conceptual models, and lack of real data in papers by J. Bjerknes and Solberg—were inhibiting worldwide adoption. Bergeron’s research output in the 1920s was aimed at addressing these concerns. His doctoral thesis, written in German, was published as a journal article in Geofysiske Publikasjoner in 1928. Here, an accessible and annotated English translation is provided along with a succinct overview of this seminal study. Major interlaced themes of Bergeron’s study were the first comprehensive description of the Bergen methods: a vigorous defense of cyclogenesis as primarily a lower-tropospheric process as opposed to an upper-tropospheric–lower-stratospheric one; a nuanced explanation of the assertion that meteorology constituted a distinct and special scientific discipline; and, very understandably, a thorough account of Bergeron’s own contributions to the Bergen School. His contributions included identifying how deformation results in frontogenesis and frontolysis, classifying the influence of aerosols on visibility, and explaining the role of the ambient conditions in the onset of drizzle as opposed to rain showers—a distinction that led the formulation of the Wegener–Bergeron–Findeisen process.
Black African Newcomer Women’s Perception of Postpartum Mental Health Services in Canada
Authors: Baiden Deborah , Evans Marilyn 
Published: June 2020

Study Background The stress of immigrating, settling into Canada, and being a new mother, may place newcomer women at risk of mental health challenges. However, little is known on Black African newcomer women’s perspectives of postpartum mental health care after experiencing childbirth in Canada. Purpose To explore sociocultural factors that impact Black African newcomer women’s perception of mental health and mental health service utilization within a year after childbirth in Canada. Methods This qualitative study, set in Southern Ontario, purposively sampled 10 African newcomer women who birthed a baby in Canada within the past year. Open-ended, semistructured interviews were conducted individually, transcribed and analyzed using thematic analysis. Results Black African newcomer women rely on mental strength, nonmedical treatment preferences, spirituality, and spousal support for fostering postpartum mental health. Furthermore, cultural beliefs, racial discrimination, and temporary immigration status impact their decision making around postpartum mental health services utilization. Conclusion Our findings suggest that Black African newcomer women use mental strength to minimize maternal mental illness. Also, the spouses of Black African newcomer women are crucial in their postpartum mental health support. There is an urgent need for culturally safe interventions to meet the postpartum mental health needs of Black African newcomer mothers.
Survey of Point-of-Care Ultrasound Uptake in Indian Neonatal Intensive Care Units: Results and Recommendations
Authors: Deshpande Sujata , Suryawanshi Pradeep , Sharma Neha , Maheshwari Rajesh , Nagpal Rema , Nagar Nandini , Gupta Samir 
Published: June 2020

Objectives: Point-of-care ultrasonography (POCU) refers to the process of ultrasound performed at the bedside by treating physicians, for the ongoing assessment of disease, evaluation of response to treatment, and assistance in procedures. This study was conducted to assess the current utilization, training, and barriers to the implementation of neonatologist-performed POCU (NP-POCU) in Indian neonatal intensive care units (NICUs). Methods: A survey questionnaire was disseminated to practicing neonatologists in India via an online survey tool from July 2017 to September 2017. The questionnaire addressed the information related to the availability of NP-POCU services, indications for its use, perception among neonatologists about its usefulness, training for NP-POCU, and access to pediatric cardiology and radiology services. Results: The overall response rate was 78%. A total of 72% respondents reported having access to NP-POCU services in their units. Neonatologist-performed POCU (NP-POCU) was used most frequently for cranial ultrasound (97%), functional echocardiography (90%), and evaluating line position (67%). Majority (92%) of the units had no training program for NP-POCU. The most common reasons cited for not having NP-POCU services were non-availability of trained personnel to perform POCU (50%) and strict Pre-conception and Prenatal Diagnostic Techniques (PC-PNDT) Act (50%). Conclusions: Neonatologist-performed point-of-care ultrasonography is being increasingly utilized in Indian NICUs. However, there is a lack of structured training and guidelines for its use. Non-availability of trained personnel and strict PC-PNDT Act are major barriers to its implementation. We recommend that accredited training programs and standardized guidelines be established for the safer use of NP-POCU in India.
Improving Care Experiences for Patients and Caregivers at End of Life: A Systematic Review
Authors: Quigley Denise D. , McCleskey Sara G. 
Published: June 2020

Background: End-of-life care is increasing as the US population ages. Approaches to providing high-quality end-of-life care vary across setting, diseases, and populations. Several data collection tools measure patient and/or caregiver care experiences at end of life and can be used for quality improvement. Previous reviews examined palliative care improvements or available measures but none explicitly on improving care experiences. We reviewed literature on improving patient and/or caregiver end-of-life care experiences. Design: We searched U.S. English-language peer-reviewed and grey literature after 2000 on adult end-of-life care experiences. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for quantitative studies, Enhancing Transparency in Reporting the Synthesis of Qualitative Research approach for qualitative studies, and Assessment of Multiple Systematic Reviews tool for the literature reviews. Setting: Palliative and hospice care. Population: Full-text abstraction of 84 articles, identifying 16 articles. Measures: Patient and/or caregiver end-of-life care experiences (captured through administrative data or direct report). Results: Articles examined palliative care experiences across settings; none studied hospice care experiences. Patients and/or caregivers assessed overall care experiences, clinician–staff interactions, provider communication, respect and trust, timeliness of care, spiritual support, caregiver knowledge of care plans, or bereavement support. Efforts aimed at improving end-of-life care experiences are limited and show mixed results. Conclusions: Literature on improving patient and/or caregiver end-of-life care experiences is emerging and focused on palliative care experiences. Evidence on improving hospice care experiences is lacking. Research on strategies for improving end-of-life care experiences should go beyond overall care experiences to include specific aspects of palliative and hospice care experiences.
Integrating Culturally Competent Advance Care Planning for Korean Immigrants: An Integrative Review
Authors: Suk Sojung , Kozachik Sharon L. , Cotter Valerie T. 
Published: June 2020

Aims: This review aims to explore the extant literature on the current utilization of ACP in Kisin order to obtain a comprehensive understanding of their health disparities and to determineevidence-based best practices to integrate culturally-competent ACP for EOL care of KIs. Design: A systematic integrative review of the literature Data Sources: Four electronic databases including PubMed, the Cumulative Index of Nursing and Allied Health Literature, the Cochrane Library, and Embase. Method: The detailed search strategy for databases implicated a combination of MeSHkeywords and associated terms, which can be found in Table A.Results: Three themes emerged in relation to fundamental components in the integration of culturally-competent ACP for EOL of KIs: (1) cultural characteristics of KIs; (2) disparities in ethnic-oriented ACP and EOL care resources in KIs; and (3) KIs’ perspectives on ACP. Conclusion: The findings of this review indicate that culturally-competent ACP resources for KIsare presently quite insufficient. It is determined that much future research is needed on howculturally-competent ACP can best augment the quality of EOL care for KIs, and on howspecific interventions can effectively implement ACP in community settings. Impact: Such ongoing research dedicated to the development of feasible culturally competent practice guidelines is anticipated to markedly reduce health disparities and promote ACP in KIs. The recommendations in this review may support Korean primary HCPs, Korean health care center administrators, Korean health maintenance organizations (HMOs), Korean advance care nurse practitioners in hospice and palliative care, and nurse researchers in their work.
Reducing the vibration of bearing units of electric vehicle asynchronous traction motors
Authors: Migal Vasiliy , Lebedev Anatoliy , Shuliak Mykhailo , Kalinin Evgeniy , Arhun Shchasiana , Korohodskyi Vladimir 
Published: June 2020

The impact of the accuracy class of bearings, rotational speed, load, clearances, and fits on the vibration levels of electric motor bearing units is investigated. The ways to reduce the vibrations of mechanical origin are offered. The boundary vibration levels of asynchronous motors limited by vibration levels of 40 dB at a frequency of 5 Hz and 80 dB at a frequency of 10,000 Hz are determined. The effect of increasing the rotational speed and load on the vibration levels of bearing units has been determined, and reserves for reducing vibration while ensuring the optimum bearing preload on the shaft journal have been identified. It is established that the clearance between the cap and the bearing when it is fixed in the housing (primer) does not ensure the unambiguity of the bearing unit assembly, which results in a large variation in vibration levels compared with rigid and elastic fixation. The results of this research can be applied to all types of traction electric motors.
Pre-operative conjunctival flora in patients with local and/or systemic risk factors for post cataract surgery infection in Northern Italy
Authors: Bruttini Carlo , Pallone Carlotta , Verticchio Vercellin Alice , Acerbi Giovanni , Baschetti Santina , Bruttini Pietro , Riva Ivano , Quaranta Luciano 
Published: June 2020

Purpose: To investigate the pre-operative conjunctival flora in patients undergoing cataract surgery with major local and/or systemic risk factors for developing post-operative infection. Methods: A total of 83 patients underwent bacterial culture and sensitivity testing of conjunctival swabs obtained from both eyes because of local risk factors at the pre-operative visit (i.e. chronic blepharitis, conjunctivitis, or lacrimal system disease), and/or systemic risk factors (i.e. autoimmune or skin disorders) for developing post-operative infection. If the swab was found positive, an antimicrobial susceptibility test was performed, and a specific antibiotic therapy was administered. Surgery was performed when a repeat conjunctival swab (after antibiotic treatment) showed negative cultures. Results: Cultures were found positive in 25.3% of patients. Staphylococcus aureus (18%) and Staphylococcus epidermidis (15%) were the most frequently isolated microorganisms. Gram-negative bacteria, including Pseudomonas aeruginosa, were present in nine cases (8%). Conclusion: Present results showed a low rate of swab positivity compared to previous published data, and slightly different microbial flora. The differences observed may be caused by geographical factors and/or to the specific characteristics of the subgroup of studied patients. Considering that the surface microbial flora is one of the major causes of endophthalmitis, this information may be useful in selecting antibacterial regimens to prevent serious ocular infections, and restrain the increasing problem of antibiotic resistance.
Automatic Planning for Nasopharyngeal Carcinoma Based on Progressive Optimization in RayStation Treatment Planning System
Authors: Yang Yiwei , Shao Kainan , Zhang Jie , Chen Ming , Chen Yuanyuan , Shan Guoping 
Published: June 2020

Objective: To evaluate and quantify the planning performance of automatic planning (AP) with manual planning (MP) for nasopharyngeal carcinoma in the RayStation treatment planning system (TPS). Methods: A progressive and effective design method for AP of nasopharyngeal carcinoma was realized through automated scripts in this study. A total of 30 patients with nasopharyngeal carcinoma with initial treatment was enrolled. The target coverage, conformity index (CI), homogeneity index (HI), organs at risk sparing, and the efficiency of design and execution were compared between automatic and manual volumetric modulated arc therapy (VMAT) plans. Results: The results of the 2 design methods met the clinical dose requirement. The differences in D95 between the 2 groups in PTV1 and PTV2 showed statistical significance, and the MPs are higher than APs, but the difference in absolute dose was only 0.21% and 0.16%. The results showed that the conformity index of planning target volumes (PTV1, PTV2, PTVnd and PGTVnx+rpn [PGTVnx and PGTVrpn]), homogeneity index of PGTVnx+rpn, and HI of PTVnd in APs are better than that in MPs. For organs at risk, the APs are lower than the MPs, and the difference was statistically significant ( P < .05). The manual operation time in APs was 83.21% less than that in MPs, and the computer processing time was 34.22% more. Conclusion: IronPython language designed by RayStation TPS has clinical application value in the design of automatic radiotherapy plan for nasopharyngeal carcinoma. The dose distribution of tumor target and organs at risk in the APs was similar or better than those in the MPs. The time of manual operation in the plan design showed a sharp reduction, thus significantly improving the work efficiency in clinical application.
Decontamination of Bacillus Spores with Formaldehyde Vapor Under Varied Environmental Conditions
Authors: Choi Young W. , Sunderman Michelle M. , McCauley Martha W. , Richter William R. , Willenberg Zachary J. , Wood Joseph , Serre Shannon , Mickelsen Leroy , Willison Stuart , Rupert Rich , Ortiz Jorge G. Muñiz , Casey Sara , Calfee M. Worth 
Published: June 2020

Introduction: This effort investigated formaldehyde vapor characteristics under various environmental conditions by the analyses of air samples collected over a time-course. This knowledge will help responders achieve desired formaldehyde exposure parameters for decontamination of affected spaces after a biological contamination incident. Methods: Prescribed masses of paraformaldehyde and formalin were sublimated or evaporated, respectively, to generate formaldehyde vapor. Adsorbent cartridges were used to collect air samples from the test chamber at predetermined times. A validated method was used to extract the cartridges and analyze for formaldehyde via liquid chromatography. In addition, material demand for the formaldehyde was evaluated by inclusion of arrays of Plexiglas panels in the test chamber to determine the effect of varied surface areas within the test chamber. Temperature was controlled with a circulating water bath connected to a radiator and fan inside the chamber. Relative humidity was controlled with humidity fixed-point salt solutions and water vapor generated from evaporated water. Results: Low temperature trials (approximately 10°C) resulted in decreased formaldehyde air concentrations throughout the 48-hour time-course when compared with formaldehyde concentrations in the ambient temperature trials (approximately 22°C). The addition of clear Plexiglas panels to increase the surface area of the test chamber interior resulted in appreciable decreases of formaldehyde air concentration when compared to an empty test chamber. Conclusion: This work has shown that environmental variables and surface-to-volume ratios in the decontaminated space may affect the availability of formaldehyde in the air and, therefore, may affect decontamination effectiveness.
Maternal asthma and gestational diabetes mellitus: Exploration of potential associations
Authors: Jensen ME , Barrett HL , Peek MJ , Gibson PG , Murphy VE 
Published: June 2020

Asthma and gestational diabetes mellitus are prevalent during pregnancy and associated with adverse perinatal outcomes. The risk of gestational diabetes mellitus is increased with asthma, and more severe asthma; yet, the underlying mechanisms are unknown. This review examines existing literature to explore possible links.  Asthma and gestational diabetes mellitus are associated with obesity, excess gestational weight gain, altered adipokine levels and low vitamin D levels; yet, it’s unclear if these underpin the gestational diabetes mellitus–asthma association. Active antenatal asthma management reportedly mitigates asthma-associated gestational diabetes mellitus risk. However, mechanistic studies are lacking.  Existing research suggests asthma management during pregnancy influences gestational diabetes mellitus risk; this may have important implications for future antenatal strategies to improve maternal-fetal outcomes by addressing both conditions. Addressing shared risk factors, as part of antenatal care, may also improve outcomes. Finally, mechanistic studies, to establish the underlying pathophysiology linking asthma and gestational diabetes mellitus, could uncover new treatment approaches to optimise maternal and child health outcomes.
Protease-Activated Receptor-2 Decreased Zonula Occlidens-1 and Claudin-1 Expression and Induced Epithelial Barrier Dysfunction in Allergic Rhinitis
Authors: Wang, MS Jun , Kang, MS Xue , Huang, MS Zhi-Qun , Shen, MS Li , Luo, MD Qing , Li, MS Meng-Yue , Luo, MS Li-Ping , Tu, MS Jun-Hao , Han, MS Mei , Ye Jing 
Published: June 2020

Background Protease-activated receptor-2 (PAR-2)-modulated tight junctions (TJs) have been suggested to be involved in the pathogenesis of chronic inflammatory diseases. However, immunopathogenesis remains to be investigated among patients with allergic rhinitis (AR). Objective This study sought to investigate the role of PAR-2 in the modulation of epithelial barrier function and the expression of TJs in the nasal mucosa of AR patients. Methods The expression of TJs and PAR-2 of the nasal mucosa in AR patients and control subjects by immunohistochemistry, quantitative real-time polymerase chain reaction (qRT-PCR), and western blotting. In vitro, Primary human nasal epithelial cells (pHNECs) of AR patients were stimulated by Der p1 to analyze the correlation between PAR-2 and TJs expression. Der p1-induced pHNECs were treated with the PAR-2 agonist SLIGRL-NH2 and antagonist FSLLRY-NH2. Fluorescein isothiocyanate–dextran 4 kDa detection was employed as an indicator of epithelial permeability. Results Lower expression levels of TJs in the nasal epithelium of AR patients were observed in comparison with that in control subjects. The PAR-2 level was markedly increased following treatment with 1,000 ng/mL of Der p1 for 24 hours in a cellular model of AR. The expression of PAR-2 was increased in Der p1-induced pHNECs of AR patients and correlated inversely with zonula occlidens (ZO)-1 and claudin-1. Treatment with Der p1 further downregulated TJs expression and promoted an increased epithelial permeability in Der p1-induced pHNECs. Conclusions PAR-2 could downregulate the expression of ZO-1 and claudin-1, which is involved in epithelial barrier dysfunction in AR.
Sinus Development and Pneumatization in a Primary Ciliary Dyskinesia Cohort
Authors: Pappa Andrew K. , Sullivan Kelli M. , Lopez Erin M. , Adams Katherine N. , Zanation Adam M. , Ebert Charles S. , Thorp Brian D. , Senior Brent A. , Leigh Margaret W. , Knowles Mike R. , Kimple Adam J. 
Published: June 2020

Background Primary ciliary dyskinesia (PCD) is a genetically diverse disease which causes impaired mucociliary clearance, and results in pulmonary, otologic, and rhinologic disease in affected patients. Genetic mutations in multiple genes impair the ability of patients to clear mucous from the lungs, middle ear, and sinonasal cavity and lead to chronic pulmonary and sinonasal symptoms. Methods We identified 17 PCD patients who had available CT scans. Volumes for bilateral maxillary, sphenoid, and frontal sinuses were calculated. A control population of patients who had preoperative CT scans for endoscopic endonasal resection of skull base pathology without sinonasal cavity involvement was also identified. Results The mean age of PCD was 33 and ranged from 13 to 54 years. Patients were age- and gender-matched to a control group that underwent resection of anterior skull-base tumors and had a mean age of 35 that ranged between 17–53 years old. The volumes for all thee sinus cavities were significantly smaller (p < 0.007) compared to the control population. The average Lund-Mackay score was 10.6 in the PCD cohort (range 6–16) in comparison to an average of 0.7 in the control cohort (range 0–2). Conclusions Overall sinus volumes were smaller in patients with PCD compared to our control population. Future studies will be aimed at understanding defects in sinus development as a function of specific genetic mutations in PCD patients. Ultimately, a better understanding of the underlying pathophysiology of PCD will allow us to identify the optimal treatment practices for this unique patient group.
How I treat renal anemia
Authors: Fishbane Steven , Coyne Daniel W. 
Published: June 2020

AbstractAnemia is a frequent complication of kidney disease. When severe, it causes symptoms that can be debilitating. The course of anemia tends to track the decline in kidney function, with prevalence increasing in more advanced disease. Although the most common cause is relative erythropoietin deficiency, other factors such as reduced iron availability contribute to the pathobiology. In this review, we use cases to explore the surprising complexity of decision-making in management of renal anemia.