bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atomically Dispersed Fe2 and Ni Sites for Efficient and Durable Oxygen Electrocatalysis
Authors: Yang Guiyuan , Fan Meihong , Liang Qing , He Xingquan , Zhang Wei , Asefa Tewodros 
Published: December 2024

AbstractDeveloping highly efficient, cost‐effective, and robust electrocatalysts for the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER) is paramount for the large‐scale commercialization of renewable fuel cells and rechargeable metal‐air batteries. Herein, a new ternary‐atom catalyst that is composed of paired Fe sites and single Ni sites (as Fe2−N6 and Ni−N4) coordinated onto hollow nitrogen‐doped carbon microspheres is developed. The as‐synthesized catalyst exhibits remarkable activities toward both the ORR and OER in alkaline media, with superior performances to those of the control materials that contain only Fe2−N6 or Ni−N4 sites. Density functional theory calculations and in situ infrared (IR) spectroscopic studies clearly reveal that the Fe2−N6 centers are the active sites for both ORR and OER, and their electrocatalytic activities are synergistically enhanced through optimization of their d‐band centers by the Ni−N4 sites. This ternary‐atom catalyst can potentially be a promising, alternative, sustainable catalyst to commercially used Pt‐ and Ru‐based catalysts to drive both the ORR and the OER in rechargeable zinc‐air batteries and other related applications.
Functionalized Attapulgite With Phosphaphenanthrene and Triazine‐Trione Groups for Improving Flame Retardancy of PBT Composites
Authors: Yang Wenlong , Li Ming , Zhang Yu , Zhang Zhongjie , Zheng Wenshu , Zou Yajie 
Published: December 2024

ABSTRACTIn this study, silane‐based phosphorus flame retardants (DOPO‐KH560) and silane‐based nitrogen flame retardants (TGIC‐KH550) were first synthesized via a ring‐opening addition reaction, and the DOPO‐KH560 and TGIC‐KH550 were further grafted onto the surface of ATP to obtain ATPD and ATPT flame retardants, respectively. The resulting flame retardants, ATPD and ATPT, with different phosphorus/nitrogen (P/N) ratios, were then incorporated into poly(butylene terephthalate) (PBT) at a loading of 10 wt% to improve the flame retardancy and mechanical integrity of the PBT composites. Specifically, PBT composite containing 8 wt.% ATPD and 2 wt.% ATPT achieved a V‐0 rating and an oxygen index (LOI) of 28.3%, and the peak heat release rate (pHRR) and total heat release rate (THR) decreased by 29.4% and 7.7% compared to the PBT. Due to good interfacial adhesion between ATPT and PBT matrix, the PBT/6ATPD/4ATPT composite exhibited a tensile strength of 58.7 MPa, exceeding the strength of PBT and the PBT/ATP composite by 9.7% and 8.1%, respectively. As a result, the integration of ATPD and ATPT as flame retardants not only improved fire resistance but also optimized the mechanical properties of PBT composites.
Human Impacts and Larger Geographic Area Explain the Highest Number of Non‐Native Species of Freshwater Fishes Into Brazilian Protected Area
Authors: Nabout João Carlos , Pinto Felipe Esteves , Rabelo Paulo Vitor Santos , de Carvalho Rodrigo Assis , Teresa Fabrício Barreto 
Published: December 2024

ABSTRACTNon‐native species represent a significant threat to biodiversity, particularly in aquatic environments where they are often introduced for purposes such as fishing or the aquarium trade. This study aimed to evaluate the influence of isolation and the size of federal protected areas (PAs) on the number of non‐native and native freshwater fish species in Brazilian PAs. Data from Brazilian PAs were gathered, including year of creation, buffer of human impacts around the PA, PA categories, coverage by freshwater, tourist visits, sampling sites, geographical coordinates (predictor variables) and information on the number of non‐native and native freshwater fish species (response variables). Linear regression analysis was employed to examine the influence of predictor variables on the number of non‐native and native fish species. A total of 33 different non‐native fish species were identified, with Poecilia reticulata, Hyphessobrycon eques, Hoplias lacerda and Cichla kelberi being the most widespread, occurring in 15, 7, 5 and 4 distinct PAs, respectively. The overall fish biodiversity within PAs encompassed 2670 species, with the National Park of Anavilhanas and the Environmental Protection Area of Ilha e Várzea do Paraná exhibiting the highest species richness. Greater human impact, larger coverage by freshwater and increased sampling effort were positively correlated with the number of recorded non‐native species. Factors such as year of creation, type of PA and tourist visitation did not have a significant effect. In contrast, native species exhibited a higher number of occurrences in PAs with lower human impact, longer histories, larger freshwater coverage areas and more extensive sampling efforts. These findings underscore the necessity for comprehensive management strategies to mitigate the impact of non‐native species on biodiversity within PAs.
Untangling the Impact of ESG Performance on Financing and Value in the Supply Chain: A Congruence Theory Perspective
Authors: Xu Jiawei , Lu Jianjun , Chai Li , Zhang Baofeng , Qiao Dakuan , Li Shuai 
Published: December 2024

ABSTRACTThe interdependent nature of supply chains allows a firm's financing activities to be influenced by the environmental, social, and governance (ESG) performance of the firm's supply chain partners. Drawing upon congruence theory, this paper explores the impact of ESG performance congruence among different supply chain members on both firm financial constraints and market value. This study employs response surface analysis and cluster analysis to examine the data of Chinese listed firms and their supply chains from 2009 to 2022. From the dyadic perspective of customer–supplier, the results suggest that the congruence of customer and supplier ESG performance reduces customers' financial constraints while increasing suppliers' financial constraints. The reduction in customers' financial constraints enhances customers' firm value. This study further reveals different configuration patterns of ESG performance within the supply chain from the triadic perspective of customer–focal firm–supplier. Our findings enrich the empirical research on ESG performance within supply chains, offering significant insights for managers and investors in allocating supply chain resources and formulating ESG investment strategies.
Trends in novel antiandrogen receptor signal inhibitor use and medical costs in prostate cancer
Authors: Miura Hikari , Yamamoto Hayato , Okuyama Yoshiharu , Ishi Noritaka , Tanaka Ryuma , Oishi Takuya , Yoneyama Fumiya , Hamaya Tomoko , Togashi Kyo , Fujita Naoki , Okamoto Teppei , Ohyama Chikara , Hatakeyama Shingo 
Published: December 2024

AbstractObjectiveWe aimed to examine trends in novel antiandrogen receptor signal inhibitor (ARSI) usage and medical costs by collecting real‐world big data included in The National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) Open Data, covering most of the clinical practices throughout Japan.MethodsUsage data for outpatient prescriptions from 2016 to 2021 were extracted from the NDB Open Data. Among the 459,610 million tablets/capsules prescribed, prostate cancer‐specific agents (bicalutamide, estramustine phosphate, flutamide, abiraterone, enzalutamide, apalutamide, and darolutamide) were selected to investigate the trends of usage and medical costs.ResultsIn total, 764.8 billion medications were recorded. Among these, standard dose‐adjusted prescriptions for bicalutamide, abiraterone, enzalutamide, apalutamide, darolutamide, and other vintages (estramustine phosphate, flutamide) was 276, 14.2, 18.1, 2.19, 0.34, and 20.3 million, respectively. The usage of ARSI increased significantly from 6.1% in 2016 to 16% in 2021. The medical costs for prostate cancer‐specific agents increased significantly (1.8‐fold) from 2016 to 2021. Despite the limited usage of ARSIs, a majority of the medical costs had been spent on ARSIs. Medical costs associated with ARSIs increased significantly from 59% to 89% (p < 0.001).ConclusionARSI usage and medical costs associated with prostate cancer increased significantly from 2016 to 2021. Despite the limited use of ARSIs, a considerable proportion of the medical costs for prostate cancer‐specific agents had been spent on ARSIs.
Mammography Among Women Residing in Urban Versus Rural Utah: Breast Cancer Survival
Authors: Tanner Quinn , Chang Chun‐Pin , Curtin Karen , VanDerslice James , Gren Lisa , Deshmukh Vikrant , Newman Michael , Date Ankita , Dodson Mark , Henry N. Lynn , Hashibe Mia 
Published: December 2024

ABSTRACTBackgroundAnnual or biennial breast cancer screenings are recommended for women 40 and older. Women residing in rural areas have worse breast cancer survival rates than urban women, but no study has focused on rural versus urban residence in Utah regarding breast cancer screening and mortality.MethodsCases (n = 14,516) were women aged > 39 diagnosed with a first primary invasive breast cancer between 1998 and 2017 in Utah. Controls (n = 63,117) without a history of breast cancer were matched to cases by birth year and birth state. Mammography screening status was identified by Current Procedural Terminology (CPT) codes. Logistic regression was used to assess the odds of breast cancer diagnosis. The Cox proportional hazards model was used to assess survival outcomes for rural and urban breast cancer patients based on screening status.ResultsScreening mammography usage among rural patients diagnosed with breast cancer was lower (17.7%) than urban usage (20.7%). Usage of screening mammograms resulted in higher odds of breast cancer diagnosis at localized stage rather than at a regional and distant stage. Rural breast cancer cases had a higher proportion of deaths, and a lower proportion screened, than urban breast cancer cases. Hazard ratios showed that screening mammography usage was associated with better survival among both rural (HR = 0.50, 95% CI = 0.44–0.57) and urban (HR = 0.56, 95% CI = 0.39–0.82) breast cancer cases.ConclusionScreening mammography usage was associated with better overall survival regardless of place of residence. Removing barriers and improving information regarding breast cancer screenings are needed in both rural and urban settings in Utah to increase mammography usage, with the overall goal of increasing early detection and outcomes of breast cancer.
Multiphoton Excited Fluorescence Imaging over Metal‐Organic Frameworks
Authors: Huo Qingwei , Meng Tong , Lu Xin , Li Dandan 
Published: December 2024

AbstractMultiphoton excited fluorescence (MPEF) imaging has emerged as a powerful tool for visualizing biological processes with high spatial and temporal resolution. Metal‐organic frameworks (MOFs), a class of porous materials composed of metal ions or clusters coordinated with organic ligands, have recently gained attention for their unique optical properties and potential applications in MPEF imaging. This review provides a comprehensive overview of the design, synthesis, and applications of multiphoton excited fluorescence imaging using MOFs. We discuss the principles behind the fluorescence behavior of MOFs, explore strategies to enhance their photophysical properties, and showcase their applications in bioimaging. Additionally, we address the current challenges and future prospects in this rapidly evolving field, highlighting the potential of multiphoton excited fluorescence imaging by MOFs for advancing our understanding of complex biological processes.
Transcatheter Aortic Valve Replacement: Full Unilateral Access Using the Ipsilateral Superficial Femoral Artery Is Effective
Authors: Cacela Duarte , Ramos Rúben , Fiarresga António , Rodrigues Inês , Ferreira André , Mendonça Tiago , Silva Tiago , Morais Luís , Grazina André , Teixeira Bárbara , Ferreira Rui 
Published: December 2024

ABSTRACTBackgroundAccess site complications are very common complications in transcatheter aortic valve replacement (TAVR). Usually, a second arterial sheath is placed either in the contralateral femoral artery or in the radial artery as a simplified approach. This study aimed to investigate the safety and effectiveness of a full unilateral access using the ipsilateral superficial femoral artery (iSFA) in TAVR and to determine whether it simplifies the procedure.MethodsThis single‐center retrospective audit analyzed the first 100 TAVR cases between February 2022 and January 2023 using iSFA as default secondary access. The primary outcomes included 30‐day device success, bleeding, and vascular access‐related complications. The last 100 bilateral cases and all bilateral cases (n = 656) served as controls.ResultsOf the 143 transfemoral TAVRs performed during the study period, 43 patients were excluded. The remaining 100 patients (median age, 84 years; interquartile range, 80–89 years; median EuroSCORE II, 2.46; interquartile range, 1.65–3.97) were analyzed. The vascular access‐related complication rates were 11% (main access, 55%; secondary access, 45%), with a 97% device success rate. In the control group of all bilateral cases, device success and vascular access‐related complication rates were 93% and 17%, respectively. In the experimental group, access complications were promptly managed in the catheterization laboratory. All cases requiring interventions other than manual compression were successfully managed using iSFA.ConclusionsThe total unilateral approach using iSFA was safe and effective, shortening the time to address main access complications, providing ergonomic advantages for operators, and enhancing patient comfort.
Neuro‐Behçet's Disease Masquerading as Multiple Sclerosis in a Young Male
Authors: Khodadadi Sanaz , Montazeri‐Shatouri Reyhaneh , Naser Moghadasi Abdorreza 
Published: December 2024

ABSTRACTThis case highlights the importance of considering Neuro‐Behçet's disease (NBD) in the differential diagnosis of multiple sclerosis (MS), particularly in patients presenting with neurological manifestations, abnormal magnetic resonance imaging (MRI) findings, and systemic symptoms consistent with Behçet's disease (BD).
Exploring Hydrocele of the Canal of Nuck in a Mature Woman: Beyond the Norm
Authors: Jha Saurav , Singh Sweta , Khan Sajjad Ahmed , Shah Rajat Kumar , Shrestha Pratick , Kandel Arjun , Baral Barsha , Regmi Pratik Raj 
Published: December 2024

ABSTRACTTimely diagnosis and surgical intervention are crucial in managing hydrocele of the canal of Nuck. A systematic approach, including thorough examination and appropriate imaging, followed by meticulous surgical technique, ensures successful treatment and favorable long‐term outcomes for patients.
Comprehensive Management of Rhino‐Orbito‐Cerebral Mucormycosis Post‐COVID‐19: A Case Report
Authors: Dehbozorgi Mohammad , Motazedian Gholamreza , Fallah‐Tafti Ali Mohammad , Nahaei Mehryar , Jabari Nia Ebtesam , Salari Fateme , Nabavizadeh Seyed Ali 
Published: December 2024

ABSTRACTPost‐COVID‐19 mucormycosis, particularly the rhino‐orbital‐cerebral form, can be life‐threatening. This case highlights the importance of maintaining high clinical suspicion, especially in patients with recent COVID‐19 history. Prompt diagnosis, aggressive surgical debridement, and antifungal therapy are crucial for successful management, even in patients without traditional risk factors.
McIndoe Vaginoplasty in MRKHS: Case Report and Literature Review
Authors: Shah Newton Ashish , Yadav Manish , Verma Suman , Yadav Digraj , Yadav Aalok Kumar , Ghimire Asmita , Rijal Hima , Koirala Poonam 
Published: December 2024

ABSTRACTMayer–Rokitansky–Küster–Hauser syndrome (MRKHS) is a rare congenital disorder characterized by agenesis of the uterus and upper two‐thirds of the vagina. It affects around 1 in 4000–5000 females and is of two types: type 1, also known as isolated Müllerian aplasia or Rokitansky, which involves only uterovaginal agenesis, and type 2, presents as uterovaginal agenesis along with renal, cardiac, and other organ anomalies. Despite the absence of vaginal and uterine structures, individuals with MRKHS typically present with normal secondary sexual characteristics and ovarian functions. A 26‐year‐old female presented with primary amenorrhea. Despite this, she had typical secondary sexual characteristics. Physical examination revealed normal pubic hair distribution and external genitalia, consistent with Tanner's stage 5 development. Further evaluation via magnetic resonance imaging (MRI) confirmed diagnosis of MRKHS type II, revealing the absence of the uterus and upper two‐thirds of the vagina, with normal ovaries and absent left kidney. A multidisciplinary team performed McIndoe vaginoplasty creating a successful neovagina, measuring 7 cm in length, using split‐thickness skin graft. MRKHS, a rare congenital anomaly involving Müllerian duct abnormalities, poses diagnostic and therapeutic challenges. The etiology remains unknown, but it likely stems from defective Müllerian fusion during embryologic development. Differential diagnosis from conditions like androgen insensitivity syndrome (AIS) is crucial. MRI is important in diagnosis, revealing associated anomalies. Treatment aims to restore sexual function. This case presents that MRKHS can occur with normal hormonal function and typical secondary sexual characteristics. Neovagina creation is an effective surgical intervention for young females seeking to restore sexual function.
Congenital Aortic Arch Malformation Presenting as Bilateral Pulsatile Neck Mass: A Unique Case Report
Authors: Feleke Tesfahunegn , Gedeno Gelebo , Solomon Daniel Zewdneh , Hailu Samuel Sisay 
Published: December 2024

ABSTRACTVascular malformations of the aortic arch and its main branches such as cervical aortic arch and high‐riding brachiocephalic artery can present as pulsatile neck swelling. Although this entity is rare, an initial Doppler ultrasound is suggested before intervention to avoid complications from unidentified aberrant vessels.
Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low‐Resource Setting
Authors: Nkenguye William , Mremi Alex , Minja Peter , Lodhia Jay 
Published: December 2024

ABSTRACTOvarian yolk sac tumors (OYSTs), also known as endodermal sinus tumors, are rare and highly malignant germ cell tumors, accounting for approximately 1% of all ovarian cancers. They predominantly affect children and young adults, with a rapid growth rate and early metastasis, making early diagnosis and treatment crucial. This report presents the case of a 6‐year‐old female from a low‐resource setting who initially presented with symptoms suggestive of acute appendicitis, including abdominal pain, fever, and vomiting. This was supported by a CT scan; however, intraoperative findings revealed a large right ovarian mass, which was surgically excised via cystectomy and histologically confirmed as an OYST. The patient recovered well postoperatively and was referred for oncological management. This case underscores the importance of considering OYSTs in the differential diagnosis of pediatric abdominal masses and highlights the necessity of a multidisciplinary approach for optimal patient outcomes. Enhanced awareness and improved diagnostic strategies are essential for better management of this rare tumor, particularly in resource‐limited settings.
Functional Class II Treatment Simultaneous With Selective Reduction of Talon Cusps: A Case Report
Authors: Yaghoutiazar Sahar , Yadegari Atiye , Esmaeili Saharnaz , Hajizadeh Alireza , Shahbazi Soheil 
Published: December 2024

ABSTRACTSelective reduction of bilateral nonsyndromic talon cusps in an 11‐year‐old class II patient enabled successful mandibular repositioning with a twin block appliance. This approach achieved desired orthodontic outcomes without causing pain or sensitivity following reduction, highlighting a novel strategy for managing talon cusps in orthodontic treatment.
Exploring DES‐Water Mixtures for Improved ADH‐CHMO Fusion Enzyme Performance in Linear Cascades
Authors: Ma Yu , Vernet Guillem , Zhang Ningning , Kara Selin 
Published: December 2024

AbstractThe application of multienzyme cascade reactions in nonaqueous media has garnered attention due to their potential in Green Chemistry. Deep eutectic solvents (DESs) have emerged as a novel alternative with high tunability. This study investigated the use of fusion enzymes, combining an alcohol dehydrogenase (ADH) and a cyclohexanone monooxygenase (CHMO), for a linear cascade stepwise oxidation of cyclohexanol to ɛ‐caprolactone with in situ cofactor regeneration in DES‐water mixtures. The stability of fusion enzymes was determined in the two DESs comprising glycerol and betaine or choline acetate at the same molar ratio (Bet–Gly, ChAc–Gly, 1:2) with various water contents (20–80 vol.%), as well as in pure buffer for comparison. Bet–Gly significantly improved enzyme thermostability at ≥40 vol.% water and doubled the half‐life time of CHMO, whereas ChAc–Gly showed a deleterious effect. The improved thermostability promoted the further optimization of the cascade reaction while addressing the high viscosity of DESs through increasing water ratios and temperatures. The reaction efficiency in DES‐buffer mixtures was comparable to the pure buffer system (97.0% yield in 24 h), while product hydrolysis was completely avoided. High substrate loadings (8 g/L cyclohexanol) and extended substrate ranges were accomplished. These findings highlight the potential of DES‐enriched media to improve catalytic efficiency and further advance sustainable biocatalytic processes.
Porous Copper‐PTFE Hybrid Electrocatalyst for CO2 Reduction with High C2+ Selectivity
Authors: Seki Yoshitomo , Nakabayashi Mamiko , Sugiyama Masakazu , Minegishi Tsutomu 
Published: December 2024

AbstractThe electrochemical CO2 reduction reaction (CO2RR) to ethylene (C2H4) is one of the most promising approaches to obtaining value‐added C2+ hydrocarbons without net CO2 emission. However, issues still to be solved for practical use include the improvement of Faradaic efficiency (FE) towards C2H4, electrode durability, and suppression of competitive hydrogen evolution reaction (HER). In this work, hydrophobic polymer, polytetrafluoroethylene (PTFE), added porous Cu electrocatalysts were firstly and successfully prepared on gas diffusion layer, and the significant enhancement of FEs toward C2+ products, especially C2H4, and durability were found. CO2RR test in flow cell as a gas diffusion electrode (GDE) revealed that the GDE with porous Cu electrocatalysts showed higher FE(C2H4) to FE(CO) while significant HER and instability issues remained. Further modification by PTFE to form porous Cu‐PTFE hybrid structure significantly decreased FE(H2) to 11.6 % in minimum, enhanced FE(C2H4) to 51.1 % in maximum and raised durable CO2RR for over 24 hours under current density of −300 mA cm−2. PTFE addition should form a secured pathway for gas species, including both reactant and product which was beneficial for durable and selective C2H4 production. This work highlights chemical engineering aspects of CO2RR including the transportation of reactants and products.