bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mid-term survivorship and patient-reported outcomes of robotic-arm assisted partial knee arthroplasty
Authors: Burger Joost A. , Kleeblad Laura J. , Laas Niels , Pearle Andrew D. 
Published: December 2019

Aims Limited evidence is available on mid-term outcomes of robotic-arm assisted (RA) partial knee arthroplasty (PKA). Therefore, the purpose of this study was to evaluate mid-term survivorship, modes of failure, and patient-reported outcomes of RA PKA. Methods A retrospective review of patients who underwent RA PKA between June 2007 and August 2016 was performed. Patients received a fixed-bearing medial or lateral unicompartmental knee arthroplasty (UKA), patellofemoral arthroplasty (PFA), or bicompartmental knee arthroplasty (BiKA; PFA plus medial UKA). All patients completed a questionnaire regarding revision surgery, reoperations, and level of satisfaction. Knee Injury and Osteoarthritis Outcome Scores (KOOS) were assessed using the KOOS for Joint Replacement Junior survey. Results Mean follow-up was 4.7 years (2.0 to 10.8). Five-year survivorship of medial UKA (n = 802), lateral UKA (n = 171), and PFA/BiKA (n = 35/10) was 97.8%, 97.7%, and 93.3%, respectively. Component loosening and progression of osteoarthritis (OA) were the most common reasons for revision. Mean KOOS scores after medial UKA, lateral UKA, and PFA/BiKA were 84.3 (SD 15.9), 85.6 (SD 14.3), and 78.2 (SD 14.2), respectively. The vast majority of the patients reported high satisfaction levels after RA PKA. Subgroup analyses suggested tibial component design, body mass index (BMI), and age affects RA PKA outcomes. Five-year survivorship was 98.4% (95% confidence interval (CI) 97.2 to 99.5) for onlay medial UKA (n = 742) and 99.1% (95% CI 97.9 to 100) for onlay medial UKA in patients with a BMI < 30 kg/m2 (n = 479). Conclusion This large single-surgeon study showed high mid-term survivorship, satisfaction levels, and functional outcomes in RA UKA using metal-backed tibial onlay components. In addition, favourable results were reported in RA PFA and BiKA. Cite this article: Bone Joint J 2020;102-B(1):108–116
The Metastatic Early Prognostic (MEP) score
Authors: Downie Samantha , Lai Florence Y. , Joss Judith , Adamson Douglas , Jariwala Arpit C. 
Published: December 2019

Aims The early mortality in patients with hip fractures from bony metastases is unknown. The objectives of this study were to quantify 30- and 90-day mortality in patients with proximal femoral metastases, and to create a mortality prediction tool based on biomarkers associated with early death. Methods This was a retrospective cohort study of consecutive patients referred to the orthopaedic department at a UK trauma centre with a proximal femoral metastasis (PFM) over a seven-year period (2010 to 2016). The study group were compared to a matched control group of non-metastatic hip fractures. Minimum follow-up was one year. Results There was a 90-day mortality of 46% in patients with metastatic hip fractures versus 12% in controls (89/195 and 24/192, respectively; p < 0.001). Mean time to surgery was longer in symptomatic metastases versus complete fractures (9.5 days (SD 19.8) and 3.4 days (SD 11.4), respectively; p < 0.05). Albumin, urea, and corrected calcium were all independent predictors of early mortality and were used to generate a simple tool for predicting 90-day mortality, titled the Metastatic Early Prognostic (MEP) score. An MEP score of 0 was associated with the lowest risk of death at 30 days (14%, 3/21), 90 days (19%, 4/21), and one year (62%, 13/21). MEP scores of 3/4 were associated with the highest risk of death at 30 days (56%, 5/9), 90 days (100%, 9/9), and one year (100%, 9/9). Neither age nor primary cancer diagnosis was an independent predictor of mortality at 30 and 90 days. Conclusion This score could be used to predict early mortality and guide perioperative counselling. The delay to surgery identifies a potential window to intervene and correct these abnormalities with the aim of improving survival. Cite this article: Bone Joint J. 2020;102-B(1):72–81
The use of the Ganga Hospital Score to predict the treatment and outcome of open fractures of the tibia
Authors: Parikh Sunny , Singh Harendra , Devendra Agraharam , Dheenadhayalan Jayaramaraju , Sethuraman Arvinth S. , Sabapathy Raja , Rajasekaran Shanmuganathan 
Published: December 2019

Aims Open fractures of the tibia are a heterogeneous group of injuries that can present a number of challenges to the treating surgeon. Consequently, few surgeons can reliably advise patients and relatives about the expected outcomes. The aim of this study was to determine whether these outcomes are predictable by using the Ganga Hospital Score (GHS). This has been shown to be a useful method of scoring open injuries to inform wound management and decide between limb salvage and amputation. Methods We collected data on 182 consecutive patients with a type II, IIIA, or IIIB open fracture of the tibia who presented to our hospital between July and December 2016. For the purposes of the study, the patients were jointly treated by experienced consultant orthopaedic and plastic surgeons who determined the type of treatment. Separately, the study team (SP, HS, AD, JD) independently calculated the GHS and prospectively collected data on six outcomes for each patient. These included time to bony union, number of admissions, length of hospital stay, total length of treatment, final functional score, and number of operations. Spearman’s correlation was used to compare GHS with each outcome. Forward stepwise linear regression was used to generate predictive models based on components of the GHS. Five-fold cross-validation was used to prevent models from over-fitting. Results The mean follow-up was 11.4 months (3 to 31). The mean time to union was 9.7 months (3 to 21), the mean number of operations was 2.8 (1 to 11), the mean time in hospital was 17.7 days (5 to 84), the mean length of treatment was 92.7 days (5 to 730), the mean number of admissions was 1.7 (1 to 6), and the mean functional score (Lower Extremity Functional Score (LEFS)) was 60.13 (33 to 80). There was a significant correlation between the GHS and each of the outcome measures. A predictive model was generated from which the GHS could be used to predict the various outcome measures. Conclusion The GHS can be used to predict the outcome of patients who present with an open fracture of the tibia. Our model generates a numerical value for each outcome measure that can be used in clinical practice to inform the treating team and to advise patients. Cite this article: Bone Joint J 2020;102-B(1):26–32
Cemented or uncemented hemiarthroplasty for displaced intracapsular fractures of the hip: a randomized trial of 400 patients
Authors: Parker Martyn J. , Cawley Shirley 
Published: December 2019

Aims Debate continues about whether it is better to use a cemented or uncemented hemiarthroplasty to treat a displaced intracapsular fracture of the hip. The aim of this study was to attempt to resolve this issue for contemporary prostheses. Methods A total of 400 patients with a displaced intracapsular fracture of the hip were randomized to receive either a cemented polished tapered stem hemiarthroplasty or an uncemented Furlong hydroxyapatite-coated hemiarthroplasty. Follow-up was conducted by a nurse blinded to the implant at set intervals for up to one year from surgery. Results A total of 115 patients died in the year after surgery. There was a tendency towards a slightly higher mortality in those treated with the uncemented prosthesis after one year (64 vs 51; p = 0.18). For the survivors, there was no significant difference in pain score at any of the time intervals. Patients treated using the cemented hemiarthroplasty recovered mobility better than those treated with the uncemented hemiarthroplasty (mean decrease in mobility score at one year: 1.7 vs 1.1, SD 1.9; p = 0.008). There was a tendency to more periprosthetic fractures in the uncemented group (five vs two cases; p = 0.45), but overall the need for further surgery was similar in both groups (nine vs seven cases). There were four perioperative deaths in the cemented group. Conclusion These results indicate that a contemporary cemented hemiarthroplasty gives better results than an uncemented hemiarthroplasty for patients with a displaced intracapsular fracture of the hip. When the condition of the patient permits, a cemented hemiarthroplasty should be used. Cite this article: Bone Joint J. 2020;102-B(1):11–16
O ENADE e a formação do professor de literatura
Authors: Santana Andréia Da Cunha Malheiros 
Published: December 2019

Este artigo tem como principal objetivo compreender como o ENADE (Exame Nacional de Desempenho de Estudantes) avalia a formação dos professores na área de leitura e literatura e os efeitos disso nos currículos dos cursos de licenciatura em Letras. Tendo em vista esse objetivo, a pesquisa busca identificar as questões que envolvem a temática da leitura e da literatura nos exames realizados nos anos de 2005, 2008, 2011 e 2014. Parte-se da premissa de que o modo como o ENADE aborda a leitura e a literatura influencia os cursos de formação de professores, desta forma interfere no próprio ensino destes conteúdos. Trata-se de uma pesquisa mista, que articula dados quantitativos com dados qualitativos. A fundamentação teórica articulou as leituras de diferentes temas como a legislação (DCN e SINAES), o controle exercido pela avaliação externa (Madaus, Scaramucci) e autores que trabalham com a literatura e o seu ensino (Candido, Jouve, Colomer). Como conclusão, foi possível destacar que o exame também precisa ser avaliado, pois tem ultrapassado os objetivos para os quais foi criado, na medida em que vem realizando uma seleção curricular de alguns conhecimentos e privilegiando alguns temas em detrimento de outros, o que interfere negativamente na formação de professores.
TERAPIA ASSISTIDA POR ANIMAIS (TAA) OU ATIVIDADE ASSISTIDA POR ANIMAIS (AAA): INCORPORAÇÃO NAS PRÁTICAS INTEGRATIVAS E COMPLEMENTARES NO SUS
Authors: Nicoletti Maria Aparecida , Rodrigues Manuel Priscila 
Published: December 2019

A Terapia Assistida por Animais (TAA) é um recurso terapêutico que utiliza a relação humano-animal na promoção da saúde física, social e emocional, bem como para melhorar as funções cognitivas das pessoas. Uma revisão da literatura foi realizada sobre resultados da Terapia Assistida por Animais em diferentes enfermidades. Foi realizada revisão do tipo narrativa sobre Terapia Assistida por Animais em bases científicas de dados como: Scientific Electronic Library (SciELO), US National Library of Medicine – National Institutes of Healh (Pubmed), Scifinder (MedLine), sites institucionais nacionais e internacionais de interesse. A Terapia Assistida por Animais ou Atividade Assistida por Animais (AAA) é utilizada como intervenção em diferentes níveis de cuidados e de pessoas. Dentre os principais benefícios, podem ser citados: diminuição da frequência cardíaca e pressão arterial; melhora do humor do paciente e da própria equipe de profissionais; favorecimento da humanização no ambiente hospitalar; diminuição da percepção da dor; queda nos níveis de colesterol; promoção de bem-estar; melhora nas relações interpessoais; redução de depressão e demência; melhora na linguagem verbal e na condição motora. Assim, com base nas experiências, pode ser sugerida a inclusão desta prática no Sistema Único de Saúde por meio da Politica de Práticas Integrativas e Complementares.
Assessment of subclinical hypothyroidism for a clinical score and thyroid peroxidase antibody: a comparison with euthyroidism grouped by different thyroid-stimulating hormone levels
Authors: Abdulateef Darya S. , Mahwi Taha O. 
Published: December 2019

Abstract

Background
Subclinical hypothyroidism (SCH) might have many symptoms of hypothyroidism. The controversy appears to lower the level of thyroid-stimulating hormone (TSH) and group subjects with TSH of more than 3 or even 2.5 mIU/L as SCH subjects.

Objectives
To assess SCH subjects both clinically using Zulewski clinical score and biochemically and to evaluate whether the euthyroid subjects with high-normal TSH (HNT) have any clinical symptom or subnormal biochemical finding.

Methods
A prospective cross-sectional study of 233 subjects, 67 with SCH and 166 euthyroidism, was conducted. Euthyroid subjects were divided according to the level of TSH as HNT (>2.5 mIU/L) and low-normal TSH (0.5–2.5 mIU/L). The subjects were examined for clinical feature including Zulewski clinical score and biochemical evaluations including thyroid peroxidase antibody (TPO-Ab) titer. The comparisons between groups were assessed using independent sample t test, and correlations between variables were evaluated using Pearson correlation.

Results
A significantly higher clinical score and higher frequencies of symptoms were found in the SCH group compared to the euthyroid group. The most frequent symptom was fatigue. Euthyroid subjects with HNT were found to have higher TPO-Ab titers than those with low-normal TSH, P < 0.05. The Zulewski clinical score was positively correlated with TSH and TPO-Ab titer but negatively correlated with the FT4 level, P < 0.05.

Conclusions
Zulewski clinical score is higher in SCH subjects compared to euthyroid subjects and can aid in assessing SCH subjects. A significant correlation exists between Zulewski clinical score and each of the TSH, FT4, and TPO-Ab titer levels. The frequency of TPO-Ab positivity is high in SCH. Additionally, euthyroid with higher TSH levels has higher level of TPO-Ab titer but not higher clinical score.
Common orthopedic problems in the neonate: a comparative study of 2 periods at a tertiary-care hospital
Authors: Sirisabya Anongnart , Tooptakong Tanteera , Limpaphayom Noppachart 
Published: December 2019

Abstract

Background
In 1975, King Chulalongkorn Memorial Hospital (KCMH) in Bangkok, Thailand, published data on common orthopedic problems in neonates.

Objectives
To determine the more recent incidence of these conditions and to compare the results with those reported 40 years ago by KCMH. The data were also compared with a recent report from Siriraj Hospital.

Methods
We reviewed medical records of newborn infants from 2012 to 2016, all of whom were born in KCMH with deformities of upper and lower extremities or other birth-related injuries. The cases were grouped according to International Classification of Diseases, 10th edition. The incidence of common neonatal orthopedic problems was calculated as cases per 1,000 live births and compared, using a chi-squared test, with the earlier data from KCMH and with the data recently reported by Siriraj hospital.

Results
Of the 24,825 live births, 54% were male and 46% were female. The average birth weight was 3,052.2 ± 516.1 g (range, 535–5,320 g) for infants. The most common deformity was postural clubfoot, followed by calcaneovalgus and hip dysplasia, with incidences of 1.37, 0.93 and 0.52 per 1,000 live births, respectively. The incidence of calcaneovalgus, metatarsus adductus, and clubfoot was lower than in the 1975 study and in the report from Siriraj. In all 3 studies, the incidence of birth-related injury was similar and clavicular fracture was the most common, with a rate of 1.3/1,000 live births.

Conclusion
The incidence of common neonatal orthopedic problems varies among institutions. Birth-related injury is a major challenge. The results may be utilized as updated data and as a starting point for parental education.
Distinguishing magnetic resonance imaging features between idiopathic hypertrophic pachymeningitis and secondary hypertrophic pachymeningitis
Authors: Warittikoon Saksith , Jakchairoongruang Ketsuda 
Published: December 2019

Abstract

Background
Hypertrophic pachymeningitis (HP) is a rare chronic inflammatory disorder characterized by marked fibrous thickening of the cerebral and/or spinal dura mater. This condition is caused by infection, inflammation, autoimmune disorder, neoplasms, or idiopathic. Magnetic resonance imaging (MRI) may play an important role in differentiating idiopathic HP from secondary HP, may avoid unnecessarily invasive dural biopsy, and prompt specific treatment.

Objective
To determine the specific MRI findings for differentiation between idiopathic HP and secondary HP.

Method
A total of 34 patients underwent MRI of the brain and cervical spine from January 2003 to December 2015. In all, 23 patients were diagnosed idiopathic HP and 11 patients were secondary HP. Demographic data and imaging findings reveal the following: configuration, thickness, signal intensity on T1-weighted image (T1WI), T2-weighted image (T2WI), and enhancement pattern of the lesions. The data were analyzed by T-test and Fisher’s exact test.

Result
Secondary HP were significantly located at anterior and middle cranial fossa (P = 0.033). There is no significant difference of lesions in configurations, T1 and T2 signal intensity and patterns of enhancement. There was significant and exclusive difference in T2 hypointense/dark intensity and homogeneous enhancement in idiopathic HP (75%, P = 0.044).

Conclusions
MRI may play a complimentarily important role in distinguishing idiopathic HP from secondary HP. Idiopathic HP is probably preferred diagnosis in the lesions with T2-rim pattern and T2 hypointense/dark intensity with homogeneous enhancement.
Investigation on the effect of electrode tip on formation of metal droplets and temperature profile in a vibrating electrode electroslag remelting process
Authors: Wang Fang , Baleta Jakov , Wang Qiang , Li Baokuan 
Published: December 2019

AbstractIn the present work, a transient full-coupled modelling approach has been put forward to study the effect of electrode tip on formation of metal droplets and temperature profile in the electromagnetically-controlled electroslag-remelting furnace with vibrating electrode. The electromagnetic field, momentum and energy conservation equations are solved simultaneously based on the finite volume method. The interface of slag and metal is traced using the volume of fluid approach. The results show that in the case of cone tip electrode the average dimension of metal droplets is smaller compared to the flat tip electrode. In addition, the bigger and stretched metal droplets are not observed with the cone tip electrode. The temperature fields with the cone tip electrode are distributed in a prominent periodic pattern compared to the case with flat tip electrode. The maximum temperature zone with the cone tip electrode is located along the z axial in the upper part of slag, not in the lower part. When the frequency changes from 0.17 Hz to 1 Hz, the maximum temperature reduces from 2050 K to 1985 K and the peak value of velocity decreases from 0.20 m/s to 0.125 m/s. When the vibration amplitude varies from 3mm to 6mm, the maximum temperature in the slag cover drops by 3.9% and the peak value of velocity rises by 16.7%.
Die Bedeutung der Genossenschaftlichen Managementprinzipien als rechtsformspezifischer Erfolgsfaktor für Genossenschaftsbanken
Authors: Walther Gerhard , Reichel Richard 
Published: December 2019

Zusammenfassung
Gerne werden die genossenschaftlichen Prinzipien als Alleinstellungsmerkmal der Genossenschaftsbanken im Wettbewerb bemüht. Doch wie ist es in der Lebenswirklichkeit der Genossenschaftsbanken um Umsetzungsintensität und Erfolgswirkung bestellt? Dieser Frage widmet sich eine empirische Untersuchung, die als Dissertation am genossenschaftlichen Forschungsinstitut in Nürnberg veröffentlich wurde (Walther, 2016). Die Untersuchung kommt zum Ergebnis, dass Förderauftrags- und Identitätsprinzip keine hohe Ausprägung in der bankgenossenschaftlichen Praxis aufweisen, während Selbsthilfe-, Selbstverantwortungs-, Selbstverwaltungs- und Regionalitätsprinzip stark ausgeprägt sind. Ein Wirkungszusammenhang der Prinzipien mit dem ökonomischen Erfolg lässt sich beim Selbsthilfe-, Selbstverantwortungs- und Selbstverwaltungsprinzip feststellen. Förderauftrags-, Identitäts- und Regionalitätsprinzip wirken kaum auf den ökonomischen Erfolg.
Enhancement of Airborne Particles Removal in a Hospital Operating Room
Authors: Wong K. Y. , M. Kamar H. , Kamsah N. 
Published: December 2019

This article presents the results of a numerical study to examine the transport of particles in an operating room equipped with an Econoclean ventilation system. Its aims are to reduce the number of particles falling onto the operating table. A simplified CFD model of the operating room was developed and validated based on the measured air velocity distribution. An SST k-ω turbulent flow model was used to simulate the airflow, while a discrete phase model was used to simulate the movement of the airborne particles. The effects of the standing posture of the surgical staff on the settlement of the particles on the operating table were examined. Results show that under the present ventilation system, when the surgical staff bend forward at an angle of 45°, the number of airborne particles that tend to fall onto the operating table increased by 1.4-fold. Adding an exhaust grille to the operating room does not have any significant effects on the distribution of the airborne particles. However, when a larger air supply diffuser is also used, the number of airborne particles that settled on the operating table was reduced 4-fold. More airborne particles are transported towards the exhaust grilles, and more airborne particles accumulate below the operating table. The present study shows that the usage of large air supply diffuser in the operating room is capable of reducing the number of airborne particles fall onto the operating table. Also, it enhances the efficiency of airborne particle removal.
A Comprehensive Genome-Wide and Phenome-Wide Examination of BMI and Obesity in a Northern Nevadan Cohort
Authors: Schlauch Karen A , Read Robert W , Lombardi Vincent C , Elhanan Gai , Metcalf William J , Slonim Anthony D ,   the 23andMe Research Team, Grzymski Joseph J 
Published: December 2019

AbstractThe aggregation of Electronic Health Records (EHR) and personalized genetics leads to powerful discoveries relevant to population health. Here we perform genome-wide association studies (GWAS) and accompanying phenome-wide association studies (PheWAS) to validate phenotype-genotype associations of BMI, and to a greater extent, severe Class 2 obesity, using comprehensive diagnostic and clinical data from the EHR database of our cohort. Three GWASs of 500,000 variants on the Illumina platform of 6,645 Healthy Nevada participants identified several published and novel variants that affect BMI and obesity. Each GWAS was followed with two independent PheWASs to examine associations between extensive phenotypes (incidence of diagnoses, condition, or disease), significant SNPs, BMI, and incidence of extreme obesity. The first GWAS examines associations with BMI in a cohort with no type 2 diabetics, focusing exclusively on BMI. The second GWAS examines associations with BMI in a cohort that includes type 2 diabetics. In the second GWAS, type 2 diabetes is a comorbidity, and thus becomes a covariate in the statistical model. The intersection of significant variants of these two studies is surprising. The third GWAS is a case vs. control study, with cases defined as extremely obese (Class 2 or 3 obesity), and controls defined as participants with BMI between 18.5 and 25. This last GWAS identifies strong associations with extreme obesity, including established variants in the FTO and NEGR1 genes, as well as loci not yet linked to obesity. The PheWASs validate published associations between BMI and extreme obesity and incidence of specific diagnoses and conditions, yet also highlight novel links. This study emphasizes the importance of our extensive longitudinal EHR database to validate known associations and identify putative novel links with BMI and obesity.