bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of 3XMM J000511.8+634018 as a new polar at Porb = 133.5 min – is it inside or outside the period gap?
Authors: Schwope A. D. , Worpel H. , Webb N. A. , Koliopanos F. , Guillot S. 
Published: March 2020

Aims. We aimed to identify the variable X-ray source 3XMM J000511.8+634018, which was serendipitously discovered through routine inspections while the 3XMM catalogue was compiled.
Methods. We analysed the archival XMM-Newton observation of the source, obtained BUSCA photometry in three colours, and performed optical spectroscopy with the LBT. These data were supplemented by archival observations from the Zwicky Transient Facility.
Results. Based on its optical and X-ray properties, 3XMM J000511.8+634018 is classified as a magnetic cataclysmic variable, or polar. The flux is modulated with a period of 2.22 h (8009.1 ± 0.2 s), which we identify with the orbital period. The bright phases are highly variable in X-ray luminosity from one cycle to the next. The source shows a thermal plasma spectrum typical of polars without evidence of a luminous soft blackbody-like component. It is non-eclipsing and displays one-pole accretion. The X-ray and BUSCA light curves show a stream absorption dip, which suggests an inclination 50° < i <  75°. The phasing of this feature, which occurs at the end of the bright phase, requires a somewhat special accretion geometry with a stream running far around the white dwarf before it is magnetically channelled. The period of this polar falls within the period gap of the cataclysmic variables (2.15−3.18 h), but appears to fall just below the minimum period when only polars are considered.
Index aus Diameter der Vena cava inferior und Aorta abdominalis bei
Neugeborenen – eine praxisrelevante Methode zur Erfassung einer
Hypovolämie
Authors: Behnke Simone , Robel-Tillig Eva 
Published: March 2020

ZusammenfassungBei kranken Neugeborenen steht häufig eine Hypovolämie im
Vordergrund der klinischen Probleme. Eine effiziente, schonende Diagnostik ist
für eine adäquate Therapie entscheidend. Sonografische
Untersuchungen entsprechen diesen Anforderungen. Um die Volumensituation der
Kinder zu beurteilen, wird eine Relation aus Durchmessern der Vena cava inferior
(IVC) und der Aorta abdominalis (Ao) erfasst.
Patienten und Methoden 97 reife, gesunde Neugeborene wurden am 1. und 3.
Tag untersucht. Es erfolgte an definierten Punkten die Messung der Diameter der
IVC, Ao und Berechnung des Index IVC/Ao. Korrelationsanalysen wurden zur
Ermittlung der Abhängigkeit der Messungen vom Geburtsgewicht und
Gewichtsverlust in den ersten 3 LT. durchgeführt.
Ergebnisse Der Durchmesser der Ao betrug am 1. Tag 6,1
(+/−0,6) mm, am 3. Tag 6,2
(+/−0,6) mm, der Diameter der IVC am 1. Tag 2,5
(+/−0,5) mm, am 3. Tag 2,6
(+/−0,5) mm. Der Index aus IVC/ Ao lag bei 0,4
(+/−0,1) am 1.Tag, 0,4 (+/−0,1)
am 3. Tag. und korreliert mit dem Geburtsgewicht. Es ließ sich ein
signifikanter Unterschied zwischen den Indices bei SGA- und LGA- Neugeborenen
feststellen (0.36 vs 0,47). Die Gewichtsabnahme von 1. zum 3. LT
(160+/−216 g) hatte keinen Einfluss auf die
Diameter und Index der Gefäße.
Schlussfolgerung Die Studie liefert Normalwerte für die Diameter
der Ao, IVC sowie des Index. Damit ist eine Einschätzung des
Volumenzustandes möglich. Die Ergebnisse können ebenso einen
Beitrag zum Verständnis der Pathophysiologie bei SGA- Neonaten sein.
Basilar Invagination: Transoral Microsurgical Endoscopically-Controlled Odontoidectomy without Palatotomy in Extreme form of Basilar Invagination
Authors: Bassiouni Hischam 
Published: March 2020

Abstract
Objective Transoral odontoidectomy in the treatment of basilar invagination is surgically challenging. Incision of the soft palate significantly increases rostral exposure of the clivus but is associated with a high incidence of speech and swallowing difficulties after surgery. We present a patient suffering from severe compression of the medulla oblongata due to an extreme form of basilar invagination treated successfully with the resection of dens via a transoral nasopharyngeal approach without palatotomy.
Setting Microsurgical endoscopic-assisted odontoidectomy through a transoral epipharyngeal approach was performed with subsequent craniocervical stabilization in a 21-year-old patient suffering from progressive myelopathy due to compression of the medulla oblongata and associated progressive syringomyelia.
Results The 21-year-old man was initially treated with suboccipital craniotomy and duroplasty in another institution. After initial improval he subsequently developed progressive ataxia, dysphagia, a bulbar speech, and weakness of the extremities. Beside ventral compression, he developed a secondary Chiari's malformation and a holospinal syringomyelia. Resection of the dens was successfully accomplished via a microsurgical transoral epipharyngeal endoscopic-controlled odontoidectomy without palatotomy. One week after odontoidectomy, posterior craniocervical stabilization was performed. All preoperative symptoms and signs improved significantly and the patient leads an independent life 4 years after odontoidectomy. On follow-up magnetic resonance imaging (MRI), the syringomyelia completely resolved.
Conclusions Palatotomy with its potential adverse effects can usually be avoided even for the treatment of extreme forms of basilar invagination.The link to the video can be found at: https://youtu.be/CBKE4n94W4g.
Integrating Stereoscopic Video with Modular 3D Anatomic Models for Lateral Skull Base Training
Authors: Barber Samuel R. , Jain Saurabh , Son Young-Jun , Almefty Kaith , Lawton Michael T. , Stevens Shawn M. 
Published: March 2020

Abstract
Introduction Current virtual reality (VR) technology allows the creation of instructional video formats that incorporate three-dimensional (3D) stereoscopic footage.Combined with 3D anatomic models, any surgical procedure or pathology could be represented virtually to supplement learning or surgical preoperative planning. We propose a standalone VR app that allows trainees to interact with modular 3D anatomic models corresponding to stereoscopic surgical videos.
Methods Stereoscopic video was recorded using an OPMI Pentero 900 microscope (Zeiss, Oberkochen, Germany). Digital Imaging and Communications in Medicine (DICOM) images segmented axial temporal bone computed tomography and each anatomic structure was exported separately. 3D models included semicircular canals, facial nerve, sigmoid sinus and jugular bulb, carotid artery, tegmen, canals within the temporal bone, cochlear and vestibular aqueducts, endolymphatic sac, and all branches for cranial nerves VII and VIII. Finished files were imported into the Unreal Engine. The resultant application was viewed using an Oculus Go.
Results A VR environment facilitated viewing of stereoscopic video and interactive model manipulation using the VR controller. Interactive models allowed users to toggle transparency, enable highlighted segmentation, and activate labels for each anatomic structure. Based on 20 variable components, a value of 1.1 × 1012 combinations of structures per DICOM series was possible for representing patient-specific anatomy in 3D.
Conclusion This investigation provides proof of concept that a hybrid of stereoscopic video and VR simulation is possible, and that this tool may significantly aid lateral skull base trainees as they learn to navigate a complex 3D surgical environment. Future studies will validate methodology.
Far Lateral Approach for Resection of Transverse Ligament Cyst
Authors: Michael Lattimore Madison , Nguyen Vincent , Basma Jaafar , Mangham William , Khan Nickalus , Sorenson Jeffrey 
Published: March 2020

Abstract
Objectives This study was aimed to describe a far lateral approach for microsurgical resection of a transverse ligament cyst, with emphasis on the microsurgical anatomy and technique.
Design A far lateral craniotomy is performed in the lateral decubitus position. After opening the dura laterally, dural sutures are placed for retraction. A stitch placed through the dentate ligament is advantageous to rotate the spinal cord to allow access to the ventral cyst. The cyst is marsupirlized and mass effect on the spinal cord is relieved. Photographs of the region are borrowed from Dr Rhoton's laboratory to illustrate the microsurgical anatomy.
Participants The first author performed the surgery and edited the video. Chart review and literature review were performed by the other authors.
Outcome Measures Outcome was assessed with postoperative neurological function.
Results The patient was discharged home after an uneventful hospital course. At short-term follow-up, the patient had a significant improvement in postoperative strength.
Conclusion The far lateral approach provides an adequate corridor to the ventrolateral brainstem in combination with utilization of the dentate ligament to reach ventral cysts compressing the spinal cord. An adequate understanding of the relevant microsurgical anatomy is a key to safe surgery in this region.The link to the video can be found at: https://youtu.be/5MGVPO2Q2pI.
The Past, Present, and Future Statuses of Formerly Classified “Atypical Pituitary Adenomas”: A Clinicopathological Assessment of 101 Cases in a Cohort of More than 1,000 Pure Endoscopically Treated Patients in Single Center
Authors: Bal Ercan , Kulaç İbrahim , Ayhan Selim , Söylemezoğlu Figen , Berker Mustafa 
Published: March 2020

Abstract
Objective This study was aimed to assess the clinical aggressiveness of pituitary neoplasms that were previously defined as atypical adenomas.
Methods A total of 1,042 pituitary adenomas were included in the study and 101 of them were diagnosed as atypical adenoma. Demographic characteristics, radiological evaluations, and clinical information were obtained from a computer-based patient database. Cases were categorized as atypical or typical using the criteria listed in 2004 Classification of Tumors of Endocrine Organs.
Results The cure and reoperation rates did not show any statistically significant difference between the typical and atypical adenomas. However, a higher Ki-67 labeling index was found to be associated with a higher rate of reoperation (p = 0.008) in atypical adenomas. Of note, cavernous sinus invasion or parasellar extension was found to be associated with lower cure rates in patients with atypical pituitary adenomas (p < 0.001 and p = 0.001, respectively).
Conclusion Although atypical pituitary adenomas are known to be more invasive, this study demonstrated that the reoperation and cure rates are the same for typical and atypical adenomas. Our findings advocate for omitting the use of atypical adenoma terminology based solely on pathological evaluation. As stated in the 4th edition of the World Health Organization (WHO) classification, accurate tumor subtyping, evaluation of proliferation by means of mitotic count and Ki-67 labeling index, and radiological and intraoperative assessments of tumor invasion should be taken into consideration in the management of such neoplasms.
Smith–Lemli–Opitz's Syndrome as a Possible Cause of Recurrent Pregnancy Loss: A Case Report
Authors: Mitra Anjali , Dolitsky Shelley , Yadava Stacy , Ashkinadze Elena 
Published: March 2020

AbstractBased on the known carrier frequency of Smith–Lemli–Opitz's syndrome (SLOS), the prevalence of this disease should be significantly higher than what is observed in the population. This may be due to a higher rate of pregnancy loss in affected embryos. Here, we present the case of a couple who underwent expanded carrier screening (ECS) after experiencing three first trimester pregnancy losses. Both parents were found to be carriers of SLOS mutations, and DNA analysis of the fetal remains of the third loss revealed the aborted fetus had inherited both the maternal and paternal mutations. This suggests SLOS as a reason for this patient's recurrent pregnancy loss (RPL), and therefore, ECS should be considered as part of the RPL work-up.
Construction of Novel Bispecific Single-Domain Antibodies (BiSdAbs) with Potent Antiangiogenic Activities
Authors: Liu Xianglei , Sun Tianyuan , Ge Qiuhan , Zhu Jianwei 
Published: March 2020

AbstractThe development of bispecific antibodies (BsAbs) has had a profound impact on cancer immunotherapy. Single-domain antibodies (SdAbs) could offer advantages over other antibody formats for the generation of a BsAbs, such as small size (∼12–15 kDa), with high affinity and specificity, superior accessibility, and high yield expression in bacteria. In this study, VEGFR2 and CD16 were chosen as the targets to construct BsAbs. As the rationale, VEGFR2 is critical for tumor-associated angiogenesis, and CD16 expressed on natural killer cells is an important target on immune cells. Humanized anti-VEGFR2 SdAb 3VGR19 and anti-CD16 SdAb C21 were combined to construct several bispecific SdAbs (BiSdAbs). The biochemical properties of the BiSdAbs were characterized. They retained the high affinity for both targets, binding selectivity, and antiangiogenic activity such as inhibition of cell proliferation, migration, endothelial tube formation, angiogenesis, and cytotoxicity to cancer cells in vitro, indicating that BiSdAbs could be a potential alternative for cancer therapy.
Knowledge in the grey zone: AI and cybersecurity
Authors: Stevens Tim 
Published: March 2020

AbstractCybersecurity protects citizens and society from harm perpetrated through computer networks. Its task is made ever more complex by the diversity of actors—criminals, spies, militaries, hacktivists, firms—operating in global information networks, so that cybersecurity is intimately entangled with the so-called grey zone of conflict between war and peace in the early twenty-first century. To counter cyber threats from this environment, cybersecurity is turning to artificial intelligence and machine learning (AI) to mitigate anomalous behaviours in cyberspace. This article argues that AI algorithms create new modes and sites of cybersecurity knowledge production through hybrid assemblages of humans and nonhumans. It concludes by looking beyond ‘everyday’ cybersecurity to military and intelligence use of AI and asks what is at stake in the automation of cybersecurity.
Carbon declines along tropical forest edges correspond to heterogeneous effects on canopy structure and function
Authors: Ordway Elsa M. , Asner Gregory P. 
Published: March 2020

SignificanceTropical forests constitute the largest terrestrial component of the global carbon budget. However, rapid agricultural expansion has left these landscapes highly fragmented, calling into question their capacity to cycle and store carbon. We utilized airborne mapping approaches that revealed changes in aboveground carbon and key aspects of ecosystem structure and function in forest edges along oil palm plantations in Malaysian Borneo. We found widespread evidence of significant changes in canopy structure and foliar traits related to light capture, growth, and productivity along forest edges that corresponded to declines in aboveground carbon. These changes underpin carbon declines that varied spatially, with far-reaching implications for the conservation of forest biodiversity and carbon stocks.
Autologous transplantation of spermatogonial stem cells restores fertility in congenitally infertile mice
Authors: Kanatsu-Shinohara Mito , Ogonuki Narumi , Matoba Shogo , Ogura Atsuo , Shinohara Takashi 
Published: March 2020

SignificanceStem cell transplantation is widely used to rescue defects in stem cell-derived cells. However, it is generally impossible to rescue tissue dysfunction caused by defective microenvironment. In this study, we report that autologous spermatogonial stem cell (SSC) transplantation rescues congenital male infertility caused byCldn11deficiency.Cldn11-deficient mice lack spermatogenesis due to defects in the blood–testis barrier. However, WT orCldn11-deficient SSC transplantation allowed development of fertile sperm from the donor cells in chemically castratedCldn11-deficient mice. Because in vivo depletion ofCldn3orCldn5restored endogenous spermatogenesis, complete spermatogenesis may be inhibited by the imbalance of claudin expression caused byCldn11deficiency. Our result suggests that some forms of male infertility can be rescued by autologous SSC transplantation.
Radical cultural specificity in translation
Authors: Strowe Anna 
Published: March 2020

Abstract
Most existing discussions of cultural specificity in translation presume that although translation may be
difficult, the meaning of culturally-specific terms is at least known. This article considers the possibility of “radical cultural
specificity,” in which the meaning of the item is inaccessible to the reader or translator and no native participant in the source
culture is available to advise. Based on the concepts of culturally-specific items from the work of Javier Aixelá and radical
translation from the work of W.V.O. Quine, I develop the notion of radical cultural specificity using examples from medieval
Celtic literature, highlighting the role of knowledge and lack of knowledge in interpretation and translation. The concept is then
briefly applied to science fiction or speculative fiction as well, suggesting that these concerns are not merely the province of
scholars of historical literature.
Decontextualisation: some issues in the Southeast Asian urban and regional spatial constructs
Authors: Boon-Thong L 
Published: March 2020

Abstract
The problem of urban system in Southeast Asian countries (with the exception of Singapore, which is a city-state) is top-heavy. In the latter case, if the larger urban region of Jabotabek is considered, Jakarta has a population of some 30 million population, making it the largest urban conurbation in Southeast Asia! What led to these macrocephalic tendencies in Southeast Asia? This keynote paper briefly reviews the overall trend of Southeast Asian urbanisation and urban growth; and asseverates that the reactions/counter-reactions to these processes have decontextualised a quintessential and important maxim – “it is the people (whether social, cultural, or physical) that matters in cities”. There are three recognisable urbanisation processes and urban growth patterns in the last five to seven decades in Southeast Asia: 1) Superinduced Metropolitan Development, 2) Extended Metropolitan Region, and 3) Urban Convolution. Some disturbing features in the current strategies. Social disparity, Fragmented solution to QOL problems, Growing lead-lag disparity and Decontextualisation at the local level. Several pertinent questions ought to be asked. Will greenfield urban space development, like smart cities and new capital cities, lose their underlying charm of informality, like the para-transits (trishaws, tut-tuts) or the popular Southeast Asian al-fresco eateries (the street food vendors and hawkers)?
Climate extremes over the maritime continent and their associations with Madden-Jullian Oscillation
Authors: Sekaranom A B , Suarma U , Nurjani E 
Published: March 2020

Abstract
Madden-Jullian Oscillation (MJO) has a strong influence towards rainfall over The Maritime Continent (MC). Due to possible impacts towards extreme precipitation in this area, a study is required to determine the influence of those processes. This research aims to investigate the influence of MJO on extreme precipitations over Indonesian Maritime Continent. To investigate the influence of those three processes, satellite precipitation data from The Tropical Rainfall Measuring Mission (TRMM) 3B42 product and Real time multivariate MJO (RMM) Index are used. Several extreme indices are calculated to identify magnitude of the extremes by calculating the area coverage of a specific precipitation threshold in each climate zone. Principal component analysis (PCA) is implemented to these indices to reduce large number of data into smaller number of information. Correlation analysis is implemented to the PCA and then matched to the MJO index to identify degree of influence of each process. Comparison of winds and mean sea level pressure data during each phenomenon is conducted to identify the key elements that control the generation of extreme precipitation. The result indicates extreme rain events in Indonesia could be triggered by the MJO, particularly during phase 4-6.
Analysis of sinking incidence in the San Luis Potosí Valley, México
Authors: Tristán A C , García M D R , Cárdenas O R , Ovalle A G C , Putri R F 
Published: March 2020

Abstract
This research focused on the geospatial method application called Synthetic Aperture Radar Interferometry (InSAR) using Sentinel 1-A satellite images to determine the sinking incidence in the San Luis Potosí - Soledad de Graciano Sánchez conurbation area. In this study was carried out the processing and comparison of the sinking values resulting from the period 2014 to 2019, where the procedures showed that the sinking incidence that occurred in some areas of San Luis Potosí Valley was 13.4 cm, which means that a sinking of approximately 2.6 cm would be generated per year in the specific areas determined, as well as, with the results of the InSAR method was made a profiles graphic of the 5 years analyzed, with the aim of observing the behavior of soil sinking in the area studied. Likewise, 72 GNSS vertices were interpolated, which served to know the ground elevations in 2014, in order to correlate their differences according to the results of the interferometry process in the images using SNAP software.
Back-propagation in the neural network of visibility estimation model based on Himawari_8 Satellite during forest fire smoke periods on Sumatera and Borneo Island, Indonesia
Authors: Imanto H , Hartono  , Marfai M A 
Published: March 2020

Abstract
Smoke from forest and land fires may significantly impair horizontal visibility, which affects a wide range of aspects of life, including human health and transportation. Satellite and its remote sensing technology can monitor a target area spatially. Visibility, one of the proxies for smoke quantifiers, has been proposed as the product of a satellite-based model that can benefit human life. This study used back-propagation in neural network (BPNN), a machine learning technology, to develop a visibility estimation model based on The Himawari-8 satellite using several combinations of BPNN tuning. It also compared the estimated visibility estimation with METAR data, as well as root mean square error (RMSE) and R2 correlation to check its accuracy. In this case, visibility was classified into three, namely class 1 visibility (below 1,600 m), class 2 (between 1,600 and 3,000 m), and class 3 (more than 3,000 m). The results showed that the highest accuracy of the visibility estimation model was obtained from the combination of input bands no. 2,4,5,11, 13, 14,15, with R2 correlation of 0.703.
Comparative Morphological Differences of Stratovolcanoes in Indonesia
Authors: Malawani M N , Subandriyo  , Handayani T , Wicaksono G N 
Published: March 2020

Abstract
The aims of this research are to identify the comparison of morphological differences of stratovolcanoes and provide informations regarding to future hazard prediction. Several stratovolcanoes are compared to investigate the differences in their morphology and then comparison on their morphological parameters are performed. The comparison of stratovolcanoes morphology is based on DEM data from DEMNAS (DEM Nasional). In this study, we see that DEMNAS already presents good data for morphological analysis in regional scale. The morphological parameters used for the comparison are landform variation, slope, and drainage pattern. Those three parameters are not directly connected to one another, but they are useful for describing the volcano edifice morphological differences. We suggest that the landform analysis is the best method for identifying morphological differences of stratovolcanoes. In addition, slope and river pattern are useful also for predicting future volcanic hazard such as pyroclastic flow and lahar.