bluuebunny/crossref_metadata_2025_split huggingface dataset:
SUBCHRONIC ORAL TOXICITY TEST FOR 28 DAYS OF SAUROPUS ANDROGYNOUS L. MERR. LEAVES SOUP IN WISTAR FEMALE RATS
Authors: AGUSLINA KIRTISHANTI  , RIDHO ISLAMIE  
Published: November 2019

Objective: The objective of the study was to evaluate the subchronic toxicity of Sauropus androgynus L. Merr. leaves soup.
Methods: Subchronic oral toxicity tests were carried out for 28 days in female Wistar rats using conventional methods. Thirty rats were divided into six groups, namely, one control group and three test groups with each extract being given at a dose of 500 mg/kg body weight (BW), 1000 mg/kg BW, and 3000 mg/kg BW, and one group satellite control and satellite test group with doses of 3000 mg/kg BW were carried out for 14 days after 28 days of treatment to see the effects of reversibility. All rat groups were observed for behavior, development of BW, serum glutamic pyruvic transaminase (SGPT), serum glutamic oxaloacetic transaminase (SGOT), creatinine serum, ratio of liver and lung organs to BW, and histology of liver and lung.
Results: The macroscopic observation of rat’s lung and rat weight ratio did not show a significant difference to the control group (p>0.05). In addition, the ratio of liver volume to BW was significantly different between the doses of 1000 mg/kg BW and 3000 mg/kg BW with satellite groups 3000 mg/kg BW (p<0.05). Levels of SGOT and SGPT as well as liver and lung histopathology scores did not show a significant difference to the control group (p>0.05). However, creatinine serum had the highest increase at a dose of 500 mg/kg BW and a dose of 1000 mg/kg BW. Reversibility effects were not seen after 14 days of the past day given Sauropus androgynous soup for 28 days in female Wistar rats.
Conclusion: The given of S. androgynous soup for 28 days for female Wistar rats did not show any specific toxicity effect so that its use was relatively safe for the consumption under 30 days. This study is expected to be the information source about the safety profile of S. androgynus leaves soup consumption.
PREDNISOLONE ENCAPSULATED SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES FOR TARGET DRUG DELIVERY – DESIGN AND QUANTIFICATION
Authors: SUBASHINI RAJARAM  , SENTHIL RAJAN DHARMALINGAM  , SANTHOSE RANI A  , SAPTHASRI R  , VARSHA D  , VINODHINI V  
Published: November 2019

Objective: The present study aimed to develop a novel type of superparamagnetic iron oxide nanoparticles (SPIONs) to deliver prednisolone at colon as a target site for the treatment of inflammatory bowel disease (IBD) such as ulcerative colitis and Crohn’s disease which may further progress to cancer.
Methods: SPIONs were synthesized using a coprecipitation method. Further, it was encapsulated with prednisolone-polyethylene glycol by double emulsion method (W1/O/W2). The prepared formulations were characterized for its physicochemical characterization such as scanning electron microscopy, X-ray diffraction, particle size and zeta potential, encapsulation efficiency, and in vitro drug release.
Results: The results reveal that the physicochemical property of the formulations complies with the standard values and in vitro release of prednisolone in the first 18 h, attains 57 and 58% and it reaches 71 and 75% at 24 h, and this is statistically significant (p˂0.0177). This release result implies that the drug release from the formulations is controllable and sustains manner.
Conclusion: Our findings could be a promising approach for the delivery of prednisolone with enhanced half-life for the treatment of IBD through colon targeting.
Ceftriaxone versus ampicillin/sulbactam for the treatment of aspiration-associated pneumonia in adults
Authors: Hasegawa Shinya , Shiraishi Atsushi , Yaegashi Makito , Hosokawa Naoto , Morimoto Konosuke , Mori Takahiro 
Published: November 2019

Aim:
To compare hospital mortality in patients with aspiration-associated pneumonia treated with ceftriaxone (CTRX) and in those treated with ampicillin/sulbactam (ABPC/SBT).
Methods:
From a Japanese multicentre observational study cohort of patients with pneumonia, those diagnosed with pneumonia and having at least one aspiration-related risk factor were selected. Propensity score-matching analysis was used to balance baseline characteristics of the participants and compare hospital mortality of patients treated with CTRX and those treated with ABPC/SBT.
Results:
Hospital mortality did not significantly differ between patients treated with CTRX and those treated with ABPC/SBT (6.6 vs 10.7%, risk difference -4.0, 95% CI [-9.4, 1.3]; p = 0.143).
Conclusion:
Further studies are needed to compare CTRX and ABPC/SBT treatments in patients with aspiration-associated pneumonia.
Area Under Curve by UV Spectrophotometric Method for Determination Albendazole in Bulk
Authors: Dagdu Kedar Vikas , Gadhave Manoj , Bhujbal Shubham , Shrinath Bhushan 
Published: November 2019

The aim of present investigation is to establish simple, precise, and rapid Spectrophotometric method for the quantification of Albendazole in Active Pharmaceutical Ingredient. In this, work is carried out to for estimation of Albendazole bulk by utilizing an Area under Curve (AUC) method using UV – Visible Spectrophotometry. The study is designed to validate the developed methods as per ICH guidelines. For this purpose the wavelength range between 200-400 nm was selected. Methanolic distilled water (50 ml methanol used for stock solution and serial dilution in 25 ml distilled water) was used as a solvent throughout the work. Linearity was obtained in concentration range 2 to 10 ɥg/ml (r2 = 0.992) for the method. The developed method was found to be simple, linear, accurate, precise and highly sensitive and which can be used for routine quality control analysis for Spectrophotometric estimation of Active Pharmaceutical Ingredient.
KeywordS: Albendazole, linearity, AUC, spectrophotometer, methanol, distilled water.
Application of training and methodological complex Electrical Engineering
Authors: Быкова Валентина Прохоровна , Bykova Valentina Prokhorovna 
Published: November 2019

The paper presents the laboratory practicum on electrical engineering and physics worked out on the basis of the teaching guide on electrical engineering including 5 test benches.
It includes 24 laboratory works with elements of independent research. The detailed and illustrated test benches of the training complex are the following: Electrical Engineering and Electronics, Electric Machines and Electric Drive, Electric Machine Assembly, Electric Energy, its Transmission and Quality, Principles of Electrical Safety. Some stands are connected to a software and hardware complex designed for measuring the studied values, reflection and processing of analog signals. The compactness and versatility of the training complex Electrical Engineering are noted; one can do 6–9 laboratory works on electrical engineering and physics at one stand. Mathematical calculations of the readings are recommended to perform in Mathcad computer algebra system.
A manual based on the laboratory works, which contains general safety rules, guidelines for per-forming tasks and requirements for their processing, is now under consideration. The advantages
of the elaborated laboratory workshop have been listed; the educational, developmental, pedagogical tasks for solving at the lesson have been analyzed; a laboratory work “Three-phase circuit connection in star scheme” is given as an example. The diagram of a star connection is presented;
a vector diagram of linear and phase voltages relations in a star connection is built. The oscillo-grams of currents under symmetrical load are illustrated. It has been noted that the individual tasks have an exploratory nature, they develop cognitive, independent and creative skills of students. The proposed methodological guidelines are recommended for specialists and bachelors in such areas as “Ship and Power Plants”, “Shipbuilding”, “Heat and Power Engineering and Heat Engineering”, etc., and can be used by teachers of general engineering disciplines
Impact of performance properties of regenerated engine oil on marine diesel wear when it runs on different grades of fuel
Authors: Тарасов Валерий , Tarasov Valery , Соболенко Анатолий , Sobolenko Anatoly 
Published: November 2019

The article focuses on studying the operational properties of regenerated engine oils in terms of the impact on the wear of friction units of the trunk diesel engine when it works on the fuel of different grades. There have been built generalized models of marine diesel parts wear on the basis of experimental studies. Diesel 2Ч10,5/13 was used for experiments. Wear was determined by the method of artificial bases and by weighting. Four groups of the main indicators
of fuels used on ships have been considered (depending on the quality indicator). The first group includes distillate fuels and low-viscosity marine fuel which is close in its characteristics to foreign fuels. The second group includes motor fuel, naval fuel oil and export fuels (medium viscosity fuels). The third group presents high-viscosity marine fuel; the fourth group - fuels made from the remains of oil refining. The description of the generalized model of details wear of the tested diesel engine was carried out by a polynomial of the second order. To obtain the model, a non-position plan was chosen for three test variables: concentration of additives in oil, a fuel quality factor and a level of diesel forcing. The superposition of the hypersurfaces of the response of wear functions
of the internal combustion engine with diesel boosting factors at zero, lower, and upper levels with visualizing the effect on engine wear parameters depending on the additives concentration and quality of the fuel used in testing regenerated engine oil has been illustrated. Verification of the model's adequacy has proved that the model is adequate for machines with average effective pressure and a wide range of fuel grades. There has been given the possibility of using the obtained model to estimate the wear value at different values of parametric factors
Three dimensional gas-dynamic calculation of nozzle block of small flow-rate centripetal turbine
Authors: Крюков Алексей , Kriukov Aleksei 
Published: November 2019

The article describes the low-consumption turbines as reliable, productive, small-sized actuating mechanisms in various units and machines. Experience in production and use
of low-cost turbine stages contributes to improving the efficiency along with simplifying and re-ducing the cost of manufacturing of the blades and the stage in general. Improving the efficiency
of low-consumption turbines requires solving the problem of aerodynamic improvement of the flow part and the calculated determination of the optimal geometry and operating modes of the impeller flow. One of the innovative ways to improve the design efficiency of low-consumption turbines is the automation of the development process using modern modeling systems based on the developed software systems. Due to the small size of the design, the design calculations of turbine stages of this type have been made in a one-dimensional formulation with the involvement of various analogies with classical stages. Using three-dimensional gas dynamic calculations based on the ANSYS CFX platform will significantly improve the quality of design of flow parts of low-flow turbines. Implementation of three-dimensional gas-dynamic calculation of the nozzle unit using the software package ANSYS CFX low-consumption turbine stage can solve this problem. The geometric model is built using AutoCAD software, the grid is selected, the boundary conditions are set. The values of the experimental coefficients of the nozzle velocity, neck velocity and the tangential component of velocity at the nozzle outlet have been compared with the coefficients obtained when using the software package. There have been built the velocity fields and made conclusions about feasibility of using the ANSYS CFX software package to determine the main parameters of a three-dimensional flow of the turbine stage.
Comparison of Predicted Amino Acid Sequences of Allatotropin/Allatostatin Receptors from Solitary to Eusocial Bee Species (Hymenoptera, Apoidea)
Authors: Yang Huipeng , Wu Jie 
Published: November 2019

Abstract
An increasingly amount of evidence supports that the evolution of eusociality is accompanies by shifts in ancient molecular and physiological pathways. The juvenile hormone, one of the most important hormones in the post-embryonic development of insects, attracts the most attention in the context of social organization. Allatoregulatory neuropeptides (Allatotropin, Allatostatin-A and Allatostatin-C) are known to regulate juvenile hormone synthesis and release in insects. In order to clarify the transitions of juvenile hormone synthesis involved in eusocial evolution, the substitutions of amino acid residues and the complexity of post-translational modifications in allatoregulatory neuropeptide receptors were characterized. Both allatotropin and allatostatin receptors are identified in all examined bee species regardless if they are solitary or eusocial. Although the amino acid sequences are highly conserved, phylogenetic results are consistent with the eusocial status. The abundance of predicted post-translational modifications correlates with social complexity except for that in allatostatin-C receptors. Even though the consequences of these specific amino acid substitutions and various post-translational modification complexity have not been studied, they likely contribute to the localizing, binding and coupling characteristics of the receptor groups.
Hubungan Antara Rasa Komunitas dengan Motivasi Kerja Pengurus Subak
Authors: Prayoga Yande , Herdiyanto Yohanes Kartika 
Published: November 2019

Subak is a traditional organization of irrigation that have been known as one of the world heritages. However, it recognition should be done with the way to accomplish real problems that happened in itself, which supposed to have particular concerns. One thing that could be done is increasing the sense of community among subak's committee so that they will have job motivation to run subak. Based on that fact, the aim of this study is to know the relationship between sense of community with job motivation among subak's committee. Methods used in this study was quantitative research methods with product-moment correlation to do data analysis. The subjects were choosen with cluster sampling technique for the total number of 58 subjects. The measurements used were sense of community modified scales from McMillan and Chavis (1986) with 34 items (cronbach's alpha is 0,898 and validity coefficient ranged from 0,314-0,637) and job motivation modified scales from Dewi (2008) with 27 items (cronbach's alpha is 0,885 and validity coefficient ranged from 0,308-0,617). The result of this study indicates that the correlation values of sense of community and job motivation is 0,696 with 0,00 probability (p<0,05). It explained that Ho rejected and Ha accepted. Those values indicates that there are positive and significant relationship between sense of community and job motivation of subak's comittee. In addition, determinant coefficient result is 0,484 that pointed the relative contribution among sense of community with job motivation is 48,4%. This result is similiar with the theory from Hughey, et.al. (1999) which reveals that sense of community will encouraged maningful results for organization. Keywords: sense of community, job motivation, work motivation and subak’s committee
GAMBARAN KEPERCAYAAN KONSUMEN DALAM BERBELANJA ONLINE DI FJB KASKUS
Authors: Sutrisna Putu Beny , Astiti Dewi Puri 
Published: November 2019

As one of the sites used for marketing products, FJB Kaskus cannot be separated from the scams that a common in e-commerce business. Nevertheless, the velocity of money in FJB Kaskus has reached 100 billion dollars each month in which the figure has even beat omzet of Amazon.com for sale to the Regional Indonesian (Hartanto, 2009). This shows the importance of trust as a major factor that must be built in order to be able to attract consumers to buying. Trust not just be recognized by the other party or e-tailers due to the trust must be created from scratch and can be proven (Rofiq, 2007). Trust cannot be easily recognized by other party or e-tailers because trust must be created from beginning and can be proven (Rofiq, 2007). This research was aimed to determine the overview of consumer trust in online shopping at FJB Kaskus. This research used qualitative methods and phenomenology design. Data were collected by using interview and observation technique with 5 respondents with experience in online shopping repeatedly at FJB Kaskus. The result of this research shows that consumer trust can be described using trusting belief and trusting intention. Besides that, website information and seller information may affect consumer trust in online shopping at FJB Kaskus. Key words: consumer trust, online shopping, FJB Kaskus.
PERAN POLA ASUH AUTORITATIF DAN PEMANTAUAN DIRI TERHADAP INTENSITAS CINTA DALAM BERPACARAN PADA REMAJA AKHIR DI FAKULTAS KEDOKTERAN UNIVERSITAS UDAYANA
Authors: Sunarto Vita , Rustika I 
Published: November 2019

Love intensity is an important element to build a commitment in a dating relationship. The success in building love intensity greatly influenced by someone’s experience with people around them included their parents. Authoritative parenting style that applied to their children influence their children’s love intensity in their relationship at late adolescent. Adolescent who has high self-monitoring increase their ability to adapt with social environment include to their boyfriend or girlfriend. The purpose of this research is to find out the role of authoritative parenting style and self-monitoring toward someone’s love intensity in a relationship at late adolescents in Faculty of Medicine Udayana University. Subjects in this research were 145 late adolescents who are dating in Faculty of Medicine Udayana University. The instruments in this research were love intensity scale, authoritative parenting style scale and self-monitoring scale. The result of multiple regression analysis shows R=0,307 (F=7,407; p<0,05) thus it can be stated that both authoritative parenting style and self-monitoring together contributes to love intensity in dating relationship. Determination coefficient = 0,094 which means the effective contribution of authoritative parenting style and self-monitoring to love intensity is 9,4%. The result of product moment correlation analysis shows correlation coefficient between authoritative parenting style and love intensity is 0,301 (p<0,05) which means that authoritative parenting style and love intensity have a positive correlation. While the result of product moment correlation analysis shows correlation coefficient between self-monitoring and love intensity is 0,154 (p<0,05) which means that self-monitoring and love intensity have a positive correlation. Keywords: love intensity, authoritative parenting style, self-monitoring, late adolescent
HUBUNGAN ANTARA POLA ASUH OTORITER DENGAN PERILAKU MENJALIN PERSAHABATAN PADA REMAJA DI DENPASAR
Authors: Purnamasari Kadek Novia , Marheni Adijanti 
Published: November 2019

Masa remaja adalah masa transisi atau peralihan dari masa kanak-kanak menuju masa dewasa. Seiring dengan perubahan yang dialami, remaja cenderung mencari jati diri dengan mencoba segala sesuatu yang belum pernah dilakukannya. Terkadang, keinginan para remaja terhalang oleh sikap orangtua dalam mengasuh anak yang masih menjunjung tinggi aturan kebudayaan, sehingga mempengaruhi hubungan antara orangtua dengan anak. Kelompok teman sebaya diakui dapat mempengaruhi pertimbangan dan keputusan seorang remaja terhadap perilakunya. Tidak sedikit anak dengan pola asuh orangtua yang otoriter cenderung menarik diri dari lingkungannya. Hal ini dapat memicu remaja untuk enggan menjalin persahabatan. Penelitian ini bertujuan untuk mengetahui hubungan yang negatif antara pola asuh otoriter dengan perilaku menjalin persahabatan pada remaja. Penelitian ini adalah penelitian kuantitatif korelasional. Subyek penelitian ini adalah remaja SMA Negeri di Denpasar sebanyak 207 orang dengan kriteria anak yang berpola asuh otoriter dan berusia antara 15-17 tahun. Metode pengambilan sampelnya dengan metode area probability random sampling. Metode analisis data yang digunakan dalam penelitian ini adalah Korelasi Product moment dari Karl Pearson. Oleh karena data hasil penelitian memiliki distribusi yang tidak normal, maka peneliti memutuskan untuk mengubah metode analisis data menjadi nonparametrik Korelasi Spearman Rank. Hasil probabilitas pada korelasi spearman rank 0,000 (p < 0,05) menunjukkan bahwa ada hubungan (signifikan) dengan kategori nilai korelasi rendah berdasarkan tabel makna nilai korelasi menurut Sugiyono 2007, dimana koefisien korelasi spearman rank-nya adalah +0,327. Hasil penelitian menunjukkan bahwa tidak ada hubungan yang negatif antara pola asuh otoriter dengan perilaku menjalin persahabatan pada remaja. Kata kunci : Pola Asuh Otoriter, Perilaku Menjalin Persahabatan, Remaja
HUBUNGAN ANTARA KONSEP DIRI DENGAN PERILAKU KONSUMTIF REMAJA DI KOTA DENPASAR
Authors: Wijayanti Astuti , Astiti Dewi Puri 
Published: November 2019

Perilaku konsumtif remaja merupakan tindakan yang terlihat secara nyata dalam mendapatkan, mengkomsumsi, dan menghabiskan barang hasil industri dan jasa tanpa batas dan lepas kendali yang ditandai dengan kehidupan mewah dan berlebihan. Perilaku konsumtif dipengaruhi oleh faktor intermal dan faktor eksternal. Salah satu faktor internal yang dimaksud adalah konsep diri, sehingga tujuan dalam penelitian ini adalah untuk mengetahui hubungan antara konsep diri dengan perilaku konsumtif remaja di Kota Denpasar. Penelitian ini menggunakan pendekatan kuantitatif, yang melibatkan remaja di Kota Denpasar yang berjumlah 318 orang dengan rentang usia 15 – 18 tahun, yang dipilih berdasarkan teknik simple random sampling. Metode pengumpulan data dalam penelitian ini menggunakan dua skala pengukuran. Skala yang pertama yaitu skala konsep diri (r : 0,895) dan skala kedua yaitu skala perilaku konsumtif (r : 0,905) Hasil pengujian hipotesis dengan menggunakan analisis regresi sederhana menunjukkan hasil rxy = -0,633. Hasil tersebut berarti bahwa terdapat hubungan negatif antara konsep diri dengan perilaku konsumtif, yang berarti bahwa semakin rendah konsep diri remaja, semakin tinggi perilaku konsumtif remaja dan begitu pula sebaliknya. Konsep diri berpengaruh sebesar 40% terhadap perilaku konsutif, sedangkan sisanya sebesar 60% dipengeruhi oleh faktor lain. Faktor lain yang dimaksud adalah yaitu kebudayaan, kelas sosial, kelompok sosial dan keluarga (Sumartono, 2002). Kata Kunci : Konsep Diri, Perilaku Konsumtif dan Remaja