bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-protective immunity of the hemagglutinin stalk domain presented on the surface of Lactococcus lactis against divergent influenza viruses in mice
Authors: Lei Han , Gao Tong , Cen Qianhong 
Published: March 2020

Abstract
Background Most of the current approaches to influenza vaccine design focus on antibodies against influenza hemagglutinin (HA). However, these influenza vaccines typically provide strain-specific protection against mostly homologous subtypes. There is an urgent need to develop a universal vaccine that confers cross-protection against influenza viruses. Of note, the HA stalk domain (HAs) is a new target for such an influenza vaccine.Results Recombinant L.lactis/pNZ8150-pgsA-HAs constructed in which pgsA was used as an anchor protein and investigated the immunogenicity of HAs, in the mouse model by oral administration without the use of a mucosal adjuvant. Mice were orally vaccinated with L.lactis/pNZ8150-pgsA-HAs, and then produced significant humoral and mucosal immune responses. Importantly, L.lactis/pNZ8150-pgsA-HAs provided significant cross-protection against H5N1, H3N2 or H1N1 virus infection.Conclusions Our data support the hypothesis that HAs presented on the surface of L. lactis can provide cross-protective immunity against influenza A viruses. Taken together, these findings suggest that L.lactis/pNZ8150-pgsA-HAs can be considered an alternative approach to developing a novel universal vaccine during an influenza A pandemic.
Yersinia enterocolitica enteritis versus other bacterial enteritis in ultrasonic findings: a single-center case control study
Authors: Miyata Eri , Jimbo Keisuke , Kyoudo Reiko , Kudo Takahiro , Shimizu Toshiaki 
Published: March 2020

Abstract
Background: Yersinia enterocolitica (Ye) causes enteritis with mesenteric lymphadenitis and terminal ileitis, and can be difficult to distinguish from acute appendicitis, especially in children. In addition, because detection from stool culture is more difficult for Ye than for other bacteria causing enteritis, the diagnosis of Ye enteritis is not easy. Abdominal ultrasonography is useful for diagnosing bacterial enteritis, including Ye enteritis. This study diagnosed Ye enteritis and other bacterial enteritis by stool culture and compared and analyzed the ultrasonic findings and clinical features in children. The aims of this study are to compare and analyze ultrasonic findings and clinical features in children with Ye enteritis and other bacterial enteritis.Methods: Participants in this retrospective study comprised all 34 bacterial enteritis patients (3-18 years old) treated between 2014 and 2017. Patients were divided into the Yersinia enterocolitica enteritis (Ye) group and other bacterial enteritis (non-Ye) group from whom other pathogens were detected. Ultrasonic findings (including maximum and minimum diameters of ileocecal lymph nodes (C-LNs), mean major/minor axis ratio, wall thickness of the terminal ileum, and presence of a pericecal hyperechoic region) and blood examinations at first visit were compared between two groups. Results: The Ye group included 13 patients and the non-Ye group included 21 patients. Mean C-reactive protein level was higher in the Ye group (5.9±3.0 mg/dL) than in the non-Ye group (2.7±3.4 mg/dL, p = 0.049). No difference in mean maximum diameter of C-LNs was seen between two groups. However, mean C-LN major/minor axis ratio was lower in the Ye group than in the non-Ye group (p = 0.002) and terminal ileal wall thickness value was higher in the Ye group than in the non-Ye group (p = 0.004). Pericecal hyperechoic region was more frequent in the Ye group than in the non-Ye group (p = 0.021). Conclusion: The combination of characteristic ultrasonic findings identified in this study may improve ultrasonic differentiation of Yersinia enterocolitica enteritis and other bacterial enteritis.
Report cards for aging and maintenance assessment of water-supply infrastructure
Authors: Sakai Hiroshi , Satake Mei , Arai Yasuhiro , Takizawa Satoshi 
Published: March 2020

Abstract
During past periods of rapid economic growth, infrastructure development in Japan was intense. This infrastructure now requires both renovation and replacement. Appropriate management of infrastructure is critical as the population falls, budgets become reduced, and staff numbers dwindle. The Japan Society of Civil Engineers evaluates infrastructure soundness and publishes the results to promote understanding of the current situation and to emphasize the importance of maintenance. We devised indices for evaluating deterioration of drinking-water distribution pipelines and maintenance management systems for the pipelines. The indices are the percentage of old pipelines, the percentage of ineffective water, change in the number of technical staff per unit length of pipe, and the repair rate of water leaks. Using these indices, the evaluation result for Japan overall was a C (Caution) in terms of deterioration and Downward in terms of maintenance management.
Influence of water diversion on spatial and temporal distribution of flow field and total phosphorus (TP) concentration field in Taihu Lake
Authors: Xu Ruichen , Pang Yong , Hu Zhibing , Zhu Tianyi , Kaisam John Paul 
Published: March 2020

Abstract
In order to evaluate the overall impact of water diversion on Taihu Lake, this paper carries out numerical simulation of the temporal and spatial distribution of the flow field and the TP concentration field in Taihu Lake based on measured data during the water diversion period by using the Euler–Lagrange method. The results show that: (1) the Pearson coefficient of monitoring points in the East Lake area increases significantly during the water diversion period, indicating that the diversion of water may indirectly influence water quality; (2) the diversion of water has a significant influence on the flow rate of the simulated stations in Taihu Lake, and the influence is Taipu (103%) &gt; Gongwan (60%) &gt;East Lake (31%); (3) when the amount of water flow transfer from the Wangyu River to the lake is greater than 100 m3/s, the mean concentration of TP in the Center and East lakes increases significantly (more than 50%). The recommended water diversion discharge is to be controlled in the range 100–200 m3/s and the total water diversion yield between 1.56 and 2.59 billion m3/a.
Overview of MPC Applications in Smart Cities
Authors: Balbis Luisella 
Published: March 2020

:
Starting from the early 2000s, the concept of Smart City emerged as a new paradigm
for urban development, driven by the exponential progress in communication and information
technology as well as by the needs of a constant growing population. The Smart City context requires
flexible infrastructures and processes, capable of reacting proactively depending on the situation.
In this paper, we seek to explore the role of model-based predictive control (MPC) in the
development of Smart Cities. The applications of MPC in different scenarios proves that this optimal
control strategy is well suited for the dynamic environment in which it operates. Nevertheless,
the literature review reveals that real life implementation of MPC as a control strategy within
urban setting is still limited and further work is needed to facilitate its adoption in a wider context
Vehicle and Pedestrian Detection Based on Multi-Level Feature Fusion in Autonomous Driving
Authors: Guoqiang Chen , Huailong Yi , Zhuangzhuang Mao 
Published: March 2020

Aims:
The factors including light, weather, dynamic objects, seasonal effects and structures bring great challenges for the autonomous driving algorithm in the real world. Autonomous vehicles can detect different object obstacles in complex scenes to ensure safe driving.

Background:
The ability to detect vehicles and pedestrians is critical to the safe driving of autonomous
vehicles. Automated vehicle vision systems must handle extremely wide and challenging scenarios.

Objective:
The goal of the work is to design a robust detector to detect vehicles and pedestrians. The
main contribution is that the Multi-level Feature Fusion Block (MFFB) and the Detector Cascade
Block (DCB) are designed. The multi-level feature fusion and multi-step prediction are used which
greatly improve the detection object precision.

Methods:
The paper proposes a vehicle and pedestrian object detector, which is an end-to-end deep convolutional neural network. The key parts of the paper are to design the Multi-level Feature Fusion Block (MFFB) and Detector Cascade Block (DCB). The former combines inherent multi-level features by combining contextual information with useful multi-level features that combine high resolution but low semantics and low resolution but high semantic features. The latter uses multi-step prediction, cascades a series of detectors, and combines predictions of multiple feature maps to handle objects of different sizes.

Results:
The experiments on the RobotCar dataset and the KITTI dataset show that our algorithm
can achieve high precision results through real-time detection. The algorithm achieves 84.61% mAP
on the RobotCar dataset and is evaluated on the well-known KITTI benchmark dataset, achieving
81.54% mAP. In particular, the detection accuracy of a single-category vehicle reaches 90.02%.

Conclusion:
The experimental results show that the proposed algorithm has a good trade-off between detection accuracy and detection speed, which is beyond the current state-of-the-art RefineDet algorithm. The 2D object detector is proposed in the paper, which can solve the problem of vehicle and pedestrian detection and improve the accuracy, robustness and generalization ability in autonomous driving.
Correlation between dietary fat consumption with body mass index and body composition (a preliminary study in community based)
Authors: Ayusari Amelya Augusthina , Wiboworini Budiyanti , Damayanti Kusmadewi Eka , Rahayu Dwi , Widardo Widardo , Lanti Yulia 
Published: March 2020

Pendahuluan: Sejumlah penelitian menunjukkan hubungan antara konsumsi lemak dengan indeks massa tubuh dan komposisi tubuh. Penelitian ini bertujuan untuk mengetahui hubungan antara konsumsi harian lemak total, asam lemak tak jenuh ganda (PUFA) dan kolesterol total dengan beberapa paramater gizi.
Metode: Penelitian ini merupakan studi cross-sectional, dengan 102 subjek. Pemeriksaan yang dilakukan adalah tinggi badan, berat badan, indeks massa tubuh dan pengukuran komposisi tubuh menggunakan timbangan komposisi tubuh Omron® HBF-212. Analisis konsumsi lemak total, asam lemak tak jenuh ganda dan kolesterol total menggunakan Software nutrisurvey 2007. Uji korelasi yang digunakan adalah Spearman Rho dengan menggunakan SpSS 21.
Hasil: Konsumsi lemak total tidak berhubungan dengan indeks massa tubuh, massa lemak total, dan massa lemak visceral. Konsumsi PUFA berhubungan secara negatif dengan indeks massa tubuh (p <0,014, -0,24) dan massa lemak total (p <0,001, -0,326), sedangkan konsumsi total kolesterol total berhubugan secara negatif dengan indeks massa tubuh (p <0,019, -0,23), dan massa lemak total (p <0,001, -0,337).
Kesimpulan: Ada hubungan antara konsumsi lemak dengan indeks massa tubuh dan komposisi tubuh. (Health Science Journal of Indonesia 2019;10(2):128-31)
Kata kunci: konsumsi lemak; indeks massa tubuh; komposisi tubuh

Abstract
Introduction: Studies showed some relation between fat consumption with body mass index and body composition. We conducted a study to investigate relationships between daily consumption of total fat, polyunsaturated fatty acid (PUFA) and total cholesterol with some nutritional parameters.
Methods: This was cross-sectional study, with 102 subjects. The study was examined height, body weight, body mass index and body composition measurements using the Omron® HBF-212 body composition monitor. There was nutrisurvey 2007 to measure total fat, polyunsaturated fatty acid and total cholesterol consumption. We analyzed the correlation by using SpSS 21 (Spearman Rho)
Results: Total fat consumption was not related to body mass index, total fat mass, and visceral fat mass. PUFA consumption was negatively associated with body mass index (p <0.014, -0.24) and total fat mass (p <0.001, -0.326), while consumption of total cholesterol was negatively associated with body mass index (p <0.019, -0.23), and total fat mass (p <0.001, -0.337)
Conclusion: There was a relation between fat consumption with body mass index and body composition.(Health Science Journal of Indonesia 2019;10(2):128-31).
Keywords: fat consumption; body mass index; body composition
The Importance of Organizational Context for the Relation Between Human Capital Investment and Firm Performance: Evidence From Labor Unions
Authors: Sunwoo Hee-Yeon , Law Justin , Lee Woo-Jong , Oh Seungbin 
Published: March 2020

ABSTRACT
We study the importance of organizational context for the relation between human capital investment and firm performance. Using unique data from Korean-listed firms, which were previously required to disclose information about union membership, we predict and find that the presence of unions attenuates the favorable relation between human capital investment and firm performance. We identify productivity, future employment, and cost behavior as channels through which this result could operate. Overall, we show that the benefits commonly associated with investments in human capital are contingent on attributes of the organization, including the presence of labor unions.
Impact of a Telephonic Intervention to Improve Diabetes Control on Health Care Utilization and Cost for Adults in South Bronx, New York
Authors: Tabaei Bahman P. , Howland Renata E. , Gonzalez Jeffrey S. , Chamany Shadi , Walker Elizabeth A. , Schechter Clyde B. , Wu Winfred Y. 
Published: March 2020

OBJECTIVE
Self-management education and support are essential for improved diabetes control. A 1-year randomized telephonic diabetes self-management intervention (Bronx A1C) among a predominantly Latino and African American population in New York City was found effective in improving blood glucose control. To further those findings, this current study assessed the intervention’s impact in reducing health care utilization and costs over 4 years.

RESEARCH DESIGN AND METHODS
We measured inpatient (n = 816) health care utilization for Bronx A1C participants using an administrative data set containing all hospital discharges for New York State from 2006 to 2014. Multilevel mixed modeling was used to assess changes in health care utilization and costs between the telephonic diabetes intervention (Tele/Pr) arm and print-only (PrO) control arm.

RESULTS
During follow-up, excess relative reductions in all-cause hospitalizations for the Tele/Pr arm compared with PrO arm were statistically significant for odds of hospital use (odds ratio [OR] 0.89; 95% CI 0.82, 0.97; P &lt; 0.01), number of hospital stays (rate ratio [RR] 0.90; 95% CI 0.81, 0.99; P = 0.04), and hospital costs (RR 0.90; 95% CI 0.84, 0.98; P = 0.01). Reductions in hospital use and costs were even stronger for diabetes-related hospitalizations. These outcomes were not significantly related to changes observed in hemoglobin A1c during individuals’ participation in the 1-year intervention.

CONCLUSIONS
These results indicate that the impact of the Bronx A1C intervention was not just on short-term improvements in glycemic control but also on long-term health care utilization. This finding is important because it suggests the benefits of the intervention were long-lasting with the potential to not only reduce hospitalizations but also to lower hospital-associated costs.
Associations Between Racial and Ethnic Groups and Foot Self-Inspection in People With Diabetes
Authors: Littman Alyson J. , Knott Catherine J. , Boyko Edward J. , Hawes Stephen E. 
Published: March 2020

OBJECTIVE
Daily foot self-inspection may permit earlier detection and treatment of a foot lesion, reducing the risk of infection and lower-limb amputation (LLA). Though race and ethnicity are strongly associated with LLA risk, with higher risk seen in African Americans (AA), American Indians/Alaska Natives (AI/AN), and Native Hawaiians/Pacific Islanders (NH/PI), associations between foot self-inspection and racial and ethnic groups are inconsistent. We aimed to assess differences in foot self-inspection among people with diabetes by race/ethnicity.

RESEARCH DESIGN AND METHODS
Using national, cross-sectional data from the 2015–2017 Behavioral Risk Factor Surveillance System surveys and including 88,424 individuals with diabetes, we estimated prevalence ratios (PRs) and associated 95% CIs of daily foot checking for sores or irritation by racial and ethnic groups using log-binomial linear regression models, after accounting for survey weights.

RESULTS
Compared with whites (who had a weighted prevalence [P] of daily foot self-inspection of 57%), AA (P 67%, PR 1.18 [95% CI 1.14, 1.23]), AI/AN (P 66%, PR 1.15 [95% CI 1.07, 1.25]), and NH/PI (P 71%, PR 1.25 [95% CI 1.03, 1.52]) had higher prevalences of daily foot self-inspection. The prevalence of daily foot inspection was significantly lower among Asians (P 35%, PR 0.62 [95% CI 0.48, 0.81]) and Hispanics (P 53%, PR 0.93 [95% CI 0.88, 0.99]) compared with whites. Associations did not vary importantly by insulin use, years since diabetes diagnosis, or having received diabetes self-management education.

CONCLUSIONS
The higher frequency of foot self-inspection in racial and ethnic groups at elevated risk of diabetes-related LLA is not sufficient to eliminate LLA disparities; additional interventions are needed to achieve this aim.
Experiences with perinatal death among midwives, obstetricians, and assistant nurses: Results from a qualitative study in Norway / Erfahrungen von Hebammen, Geburtshelfern und Kinderpflegern mit perinatalem Tod: Ergebnisse einer qualitativen Studie in Norwegen
Authors: André Beate , Dahlø Raija , Eilertsen Tina , Shorey Shefaly , Ringdal Gerd I. 
Published: March 2020

Abstract
This study aims to explore experiences of healthcare professionals, including midwives, obstetricians, and assistant nurses, after a perinatal death. A qualitative study design was used, and 20 participants were interviewed. Data were analyzed using content analysis. Three categories emerged from the data: (i) external responses, (ii) internal responses, and (iii) personal responses. Generally, there was a “culture of blame” in response to the perinatal death among the professionals. The lack of opportunity to deal with perinatal death and having an inappropriate way to handle feelings and experiences are the important findings of this study. If not well supported, the concerned healthcare professionals may face serious health challenges in the long term. Hence, supportive interventions need to be designed and evaluated to provide adequate support to the concerned professionals.
Hubungan IMT (Indeks Massa Tubuh) dengan Ketahanan (Endurance) Kardiorespirasi pada Mahasiswa Pendidikan Dokter Unand 2009-2012
Authors: Jayusfani Reny , Afriwardi Afriwardi , Yerizel Eti 
Published: March 2020

AbstrakSaat ini terjadi peningkatan kelebihan berat badan terutama pada generasi muda disebabkan oleh diet yang tidak tepat dan gaya hidup yang tidak aktif. Peningkatan berat badan ini akan berakibat pada penurunan daya tahan kardiorespirasi hingga berdampak pada kapasitas kerja fisik. Tujuan penelitian ini adalah untuk menentukan hubungan Indeks Massa Tubuh (IMT) dengan ketahanan kardiorespirasi pada mahasiswa FK Unand. Penelitian dilakukan pada mahasiswa FK Unand Padang dari Desember 2012 sampai Februari 2013. Studi observasional analitik ini menggunakan desain cross sectional study dengan jumlah subjek 30 orang. Ketahanan kardiorespirasi didapat dengan menghitung nilai VO2maks menggunakan tes ergometer sepeda metode Astrand 6 minute cycle test. Dilakukan pengukuran berat badan dan tinggi badan. Analisis statistik yang digunakan adalah uji regresi linear sederhana. Hasil penelitian menemukan bahwa rerata IMT 23,2 ± 5,1 dan rerata volume oksigen maksimal 39,5 ± 12,1. Uji regresi linear menunjukkan terdapat hubungan antara IMT dengan ketahanan kardiorespirasi dengan tingkat hubungan sedang (r=0,567, p<0,05) dengan pengaruh sebesar 32,1% (R2=0,321) dan persamaan regresi yang didapat adalah Y=70,827 – 1,349X. Kesimpulan hasil studi ini adalah semakin tinggi indeks massa tubuh semakin rendah ketahanan kardiorespirasi.Kata kunci: volume oksigen maksimal, indeks massa tubuh, ketahanan kardiorespirasi AbstractNowadays, there are many cases about increasing the weight of body, especially at younger generation. It is caused by anappropriate diet and inactive lifestyle. Increasing of weight will cause declining of cardiorespiratory endurance. So that, it will impact on physical work capacity. The objective of this study was to determine the relationship between cardiorespiratory with Body Mass Index (BMI) in medical student of Andalas University.The research was done on medical student of Andalas University Padang in December 2012 until February 2012. This research used observational study with cross sectional design study. The subject of this research were 30 people. Cardiorespiratory endurance was obtained by calculate the value of VO2max. This measurement used ergometer bicycle with the method was using Astrand 6 minute cycle test. This test measured the weight and height body. Statistical analysis was simple linear regression. The result found that the average of BMI is 23.2 ± 5.1 and an average maximum oxygen volume is 39.5 ± 12.1. Linear regression found that there is a moderate significant effect between BMI and cardiorespiratory endurance (r=0.567, p <0.05) with the effect about 32.1% (R2 = 0.321) and the regression equation was Y = 70.827 to 1.349 X.In conclusion, the subjects have average cardiorespiratory endurance level and normal body mass index. If the body of mass index is higher, the cardiorespiratory endurance
Ekspresi PDGF-B dan SCUBE 1 pada Arteri Karotis Mencit yang Diligasi dan Tidak Diligasi
Authors: Verdiana Ranti , Ali Hirowati , Kadri Husnil 
Published: March 2020

AbstrakDiffuse Intimal Thickening (DIT)terjadi sebagai adaptasi fisologis terhadap shear stress yang dapat terbentuk melalui ligasi arteri karotis. Ligasi akan menyebabkan terbentuknya penebalan tunika intima pada pembuluh darah. Penebalan tunika intima terjadi melalui proses inflamasi yang melibatkan sitokin seperti PDGF-Bdan SCUBE 1 yang terdapat di dalam trombosit dan endotel. Tujuan penelitian adalah mengetahui ekspresi PDGF-B dan SCUBE 1 pada arteri karotis mencit yang diligasi dan tidak diligasi. Desain penelitian adalah eksperimental dengan menggunakan 5 ekor mencit yang dilakukan ligasi pada arteri karotis kiri sedangkan arteri karotis kanan tidak diligasi. Kemudian, arteri karotis tersebut dikumpulkan dan diperiksa kadar PDGF-B dan SCUBE 1 dengan menggunakan PCR. Uji hipotesis yang digunakan adalah independent t-test. Hasil penelitian adalah tidak terdapat perbedaan bermakna PDGF-B pada arteri karotis mencit yang diligasi dan tidak diligasi (p = 0,66; p>0,05) dan tidak terdapat perbedaan bermakna SCUBE 1 pada arteri karotis mencit yang diligasi dan tidak diligasi (p = 0,33; p>0,05).Kata kunci: diffuse intimal thickening, DIT, PDGF-B, SCUBE 1, PCR. AbstractDiffuse Intimal Thickening (DIT) develops as physiological adaptive process of shear stress which can be performed by carotid artery ligation in mice. Ligation will cause an intimal thickening in vessel. Intimal thickening occurs through an inflammatory process that involves cytokines such as PDGF-B and SCUBE 1 that are found in platelet and endothelial cells.The objective of this study was to determine the expression of PDGF-B and SCUBE 1 in ligated and non ligated carotid artery of mice.The design study was experimental. This study used 5 mouse that were ligated in left carotid artery and non ligated in right carotid artery. Then, those carotid arteries were collected and examined PDGF-B and SCUBE 1 levels using PCR. The hypothesis test of this study was Independent t-test.The result was no significant difference between PDGF-B in ligated and non ligated carotid artery of mice (p = 0.66; p>0.05). The same result was also found in SCUBE 1 as well (p = 0.33; p>0.05).Keywords: diffuse intimal thickening, DIT, PDGF-B, SCUBE 1, PCR.