bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adherence to urate-lowering therapy while following the national guidelines for the management of patients with gout (preliminary evidence)
Authors: Chikina M. N. , Ilyinykh E. V. , Eliseev M. S. 
Published: November 2020

Low compliance in patients with gout is one of the reasons for inadequate disease control.Objective: to study treatment adherence in compliance with the national guidelines for the management of gout patients, which provide for the continuous use of urate-lowering drugs, a gradual increase in their dose until the target serum uric acid (UA) level is reached, prophylactic antiinflammatory therapy, and regular patient monitoring.Patients and methods. This was a prospective single-center study. By now, 60 of the 80 enrolled gout patients had completed the study. The follow-up period was at least 24 weeks, during which allopurinol or febuxostat was used at the final dose. During initiation of urate-lowering therapy, allopurinol 100 mg/day was prescribed, followed by dose titration to reach the target UA level (<360 μmol/L) for all patients or <300 μmol/L for those with severe tophaceous gout. Patients with ineffective allopurinol and/or in the presence of its associated adverse reactions were prescribed febuxostat (Azurix®) 80 mg/day; the dose was increased up to 120 mg/day as needed. To prevent acute arthritis attacks, all the patients received a nonsteroidal anti-inflammatory drug (NSAID) at minimal therapeutic doses or colchicine 0.5 mg/day, and in the presence of contraindications to their use, they took glucocorticoid (GC) 7.5 mg/day calculated with reference to prednisolone. The four-item Morisky–Green questionnaire was used to assess patient adherence to therapy.Results and discussion. At 24 weeks after the start of their follow-up, 53 (88%) of the 60 patients received urate-lowering therapy; 38 (72%) of these 53 patients achieved the target UA level. The dose of allopurinol was titrated in 19 patients; and 10 (53%) of them achieved the target serum UA levels. Due to its inefficacy, allopurinol was replaced by febuxostat in 24 patients. In this group, the target UA level was recorded in 16 (67%) patients. Seventeen patients were immediately prescribed febuxostat that could achieve the target UA level in 12 (71%) of them. All the patients enrolled in the study received prophylactic anti-inflammatory therapy: NSAIDs were used in 9 (15%) patients, colchicine and GC were given to 46 (77%) and 5 (8%), respectively. Twenty-six (49%) patients who had completed the investigation were ascertained to have a high adherence therapy. Moderate and low adherence was observed in 9 (17%) and 18 (34%) patients, respectively. High therapy adherence was noted in more than half of cases in the febuxostat group and in 40% in the allopurinol one.Conclusion. High compliance in gout patients can be achieved through the observance of the national guidelines for the treatment of this disease.
Mulheres negras e Necropolítica: como enfrentam a morte de seus filhos?
Authors: Souza Leticia Gomes , Castelar Marilda , Santana Karine de Souza Oliveira , Souto Verena Souza 
Published: November 2020

INTRODUÇÃO: A morte de jovens negros é o principal resultado da violência urbana. Quando esses jovens morrem deixam os seus familiares, principalmente as mães negras, em um contexto de sofrimento causado por essa perda. Nesse contexto, as mulheres negras desenvolvem formas de enfrentamento para lidar com a dor. OBJETIVO: Analisar formas de enfrentamento de mulheres negras diante do assassinato de seus filhos na capital baiana. MÉTODO: Trata-se de uma pesquisa qualitativa, do tipo documental, realizada em sites que publicaram relatos dessas mulheres entre 2014 a 2019. Os dados foram analisados a partir da análise de conteúdo, com fundamento em Minayo. Para a realização da pesquisa, fez-se o uso de documentos públicos e de acesso livre. RESULTADOS: Foram mapeados oito relatos de mães negras, sendo sete oriundos de jornais online e um em blog. Seus relatos revelam muito sofrimento psíquico, e desvelam contextos marcados por racismo, violências e violação de direitos. Nesse cenário emergiram algumas formas de enfrentamentos como a religiosidade, a busca por justiça e a percepção das mães negras diante do racismo. CONSIDERAÇÕES: Foi possível conhecer a caminhada dessas mulheres que foram atravessadas pela violência e que a partir disso construíram formas de enfrentamento e cuidado. Os resultados apontam para maior necessidade de pesquisas que investiguem mais sobre esse sofrimento e seus desdobramentos na saúde mental dessas mães.
TUBER CHARACTERISTICS OF DISEASE FREE MERISTEM CLONES OF POTATO GENOTYPES
Authors: OZTURK Gulsum , YILDIRIM Zihin 
Published: November 2020

Potato seedlings of various potato genotypes free from the following viruses PVS (potato viruses S), PVX (potato viruses X), PVY (potato viruses Y), PLRV (potato leafroll virus), PVA (potato viruses A) and PMTV (potato mop-top viruses) were obtained via meristem culture and they were increased in vitro. Seedlings were grown in the greenhouse and mini tubers obtained were tested in the seed bed and in the field trials.
When the results of greenhouse experiment were evaluated: clone Nif-1 was found to be high for single tuber number (3.0). Clone 6/7-1 had high means as compared to the remaining for single tuber weight (5.2 g) and single plant yield (14.5 g). The highest mini tuber number was obtained from Clone 6/7 in seedbed experiment. Also Hermes-1 had higher means for single tuber weight and Clone 122-1 had the higher means for plant yield and plot yield than that of other clones. Clones Atlantic-2; 3 and 1 (5.8 cm) had high tuber width and clone Hermes-1 and 2 (6.6 cm) had the highest means for tuber length in the seedbed trial. Based on the results of field experiment the highest minituber numbers were obtained from Clone 6/7-2 (10.7) and Clone 6/7-2 (10.3). Atlantic-1 (136.5 g) had high mean for tuber weight as compared to other clones. Nif-1 had the highest mean for plant yield as 920.2 g. Clone 122-1 was found to be higher than the other clones for plot yield (5.3 kg). Clones of Atlantic-1; 2 and 3 (5.9 cm) had high tuber width and clones of Juwel-1; 2 and Hermes-2 (6.8 cm) had the highest means for tuber length.
Cirurgia bariátrica, intersecções de gênero, raça e classe social
Authors: Silva Thales Philipe Rodrigues da , Dumont-Pena Érica , Matozinhos Isabela Penido , Bastos Larissa Cristina Silva , Manzo Bruna Figueiredo , Matozinhos Fernanda Penido 
Published: November 2020

Objetivo: Discutir sobre o perfil dos participantes da cirurgia bariátrica a partir das intersecções de gênero, raça e classe social. Métodos: Coorte com 387 adultos submetidos à cirurgia bariátrica entre 2012 a 2014, em hospital geral de Minas Gerais. A associação entre as variáveis estudadas foi investigada em análises estratificadas por sexo, categoria autorreferida. Resultados: Amostra foi composta predominantemente pelo sexo feminino, idade entre 31 e 45 anos e cor de pele parda. Observou-se diferença estatística entre cor de pele, renda média familiar entre os sexo. Conclusão: O predomínio da realização de cirurgias bariátricas pelo sexo feminino é pensado como integrante das relações de gênero, que se entrecruzam com as relações de raça e classe, configurando hierarquias. Torna-se necessária a articulação entre cirurgia bariátrica, educação em saúde e outras terapias que se refiram, principalmente, à liberdade de vivência do corpo com relações de gênero menos hierarquizantes e mais saudáveis.
The influence of rosella flower tea on blood pressure reduction in hypertension patients
Authors: Anggraini Siska Sakti , Nur Siti Aisyah , Morika Honesty Diana , Sari Dewi Ratna Indah 
Published: November 2020

Background: Hypertension is called the silent killer because it does not provide specific symptoms, it can increase the incidence of strokes, heart attacks, chronic kidney disease if not controlled and controlled properly. Management of hypertension is generally with pharmacological therapy that has not shown improvement. Non-pharmacological treatment using rosella flower tea which functions to open blood vessels wider, reduce blood viscosity and increase urine production so as to reduce blood volume. The purpose of this study was to study the effect of rosella tea on reducing blood pressure in hypertensive patients. Methods: This study uses a quasi-experiment design with the two-group pre-test and post-test design approach. This research was conducted on patients with hypertension at the Padang city health center with an intervention group of 16 respondents and a control of 16 respondents. Data analysis in this study used univariate and bivariate using independent t-test statistics. Results: The results of the study showed the average blood pressure in the systolic pretest intervention group 147.81 for 94.69 diastole and posttest systole 129.06 posttest diastole 78.75 while the control group for systole pretest 154.6 for diastole 96.25 and posttest without posttest treatment systole 129.06 postest diastole 78.75. Obtained a p value 0,000 statistical test for systole and a p value 0,000 diastole. Conclusions: There is an effect of rosella flower tea on reducing blood pressure in patients with hypertension at the Padang city health center.
Analysis of posture and discomfort feelings of grinders in different foundries in West Bengal
Authors: Chandan Das , Suman Das , Debamalya Banerjee , Amalendu Samanta , Kumar Bhattacharyya Bidyut 
Published: November 2020

Background: The most essential part of manufacturing the products is grinding. Health and safety of workers are the most important issues in this unit now a days. High productivity as well as maximum turnover is the highest interest of these units. Target oriented work puts some pressure on the workers that also increase their muscular and body stresses. Methods: The research work was done in different small-scale grinding units in West Bengal. The snap shot of 20 workers in different grinding units was obtained and evaluated with the help of rapid upper limb assessment. NIOSH’s discomfort survey method was used for mapping the different areas of pain, dissatisfactions during the operation. Heart rate and postural stresses were also noticed. Results: This research work also shows that the poor working conditions enhance the body stresses and the discomfort level of grinders. The highest heart rate also indicates the poor health condition of grinders. Poor environmental conditions, specially noise and heat were common in grinding units. Conclusions: It can be concluded that MSDs were present in the activities carried out in grinding units where the major number of workers were involved in bad body postures. This research work also shows that the poor working conditions enhance the body stresses and the discomfort level of grinders.
THE DETERMINANTS OF ACCESS TO ADOLESCENT- FRIENDLY HEALTH SERVICE: A CASE CONTROL STUDY
Authors: Arifah Izzatul , Kusumawardani Lenni Ayu , Hendriyaningsih Dwi , Wibisono Mukti Aji , Lestari Estu Puji 
Published: November 2020

Background: Adolescents need to access Adolescent-Friendly Health Service (AFHS) to get it’s benefit in order to improve adolescent health. However, the current adolescent access to that service remains low with the access prevalence under 50%).Aim: This study determined factors that affected adolescents’ access to AFHS.Methods: This school-based case control study was conducted in 9 junior and senior high schools in the area of Sangkrah and Kratonan in Surakarta District. There were 162 cases (who accessed the AFHS by guidance from health professionals and peer educators) and 162 controls (those who did not) who were chosen using total sampling and proportionate random sampling technique, respectively. A multiple logistic regression analysis was used to assess the determinant factors of AFHS access.Results: Access to AFHS was significantly determined by knowledge of the program and perceived demand. A probability of finding adolescents who had knowledge of the program was 6 times higher in the case group than in control group with the OR value of 6.1 (95% CI 3.3-11.1).Conclusion: Overall, the low adolescents’ access was mostly caused because of insufficient knowledge. Broadening information about the program and adolescents’ access to the program through electronic media and peer educators is required. Keywords: access, adolescent, Adolescent-Friendly Health service, AFHS.
SOVEREIGN DEBT ISSUANCE CHOICE: SUKUK VS CONVENTIONAL BONDS
Authors: Boujlil Rhada , Hassan M. Kabir , Grassa Rihab 
Published: November 2020

This paper investigates the determinants and their factors that affect governments’ decision to employ sovereign Sukuk over conventional bonds; the research is based on a sample of 143 Sukuk and 602 conventional sovereign bonds issued in 16 OIC countries from 2000 to 2015. The results depict that more nations that have developed financial markets, higher credit quality, and strong economic/financial prospects, issue sovereign Sukuk rather than sovereign conventional bonds. Dealing with Sukuk bonds can be a strategy to diversify and develop current debt markets by introducing newly-developed debt tools. However, less economically developed nations countries are typically issuing insurance for classic sovereign bonds. Our findings suggest that a government’s choice of sovereign debt is influenced mainly from national financial and macroeconomic indicators, as well as specific events. Countries with developed financial markets, strong economic indicators, high credit quality, and sustainable financial position are more likely to issue sovereign Sukuk rather than sovereign bonds as a strategy to develop and diversify their financial markets by promoting new debt products.
USER ACCEPTANCE OF ONLINE WAQF APPLICATION: EVIDENCE FROM INDONESIA
Authors: Faturohman Taufik , Hassandi Irfan , Yulianti Yulianti 
Published: November 2020

Waqf is an Islamic asset endowment to be kept in faith and used for charitable or religious purposes. Its function is to demonstrate the potential and economic benefits of waqf assets for worship and other people’s prosperity. Indonesia has great opportunities to raise more significant amounts of waqf funds. One strategy that appears effective with regard to waqf, especially cash waqf, is to provide an online service. Hence, this research attempts to analyse whether the perceived usefulness, perceived ease of use, perceived religiosity, and amount of information influences user acceptance of using an online waqf application process by implementing the technology acceptance model (TAM). Moreover, the study incorporates structural equation modelling (SEM) to interpret the path analysis of the model. The study fills the gap in the literature concerning the context of use of the technology acceptance model for online waqf in Indonesia. We find that the variables that directly influence user acceptance of online waqf application are perceived usefulness and perceived ease of use, with perceived ease of use influencing perceived usefulness. In addition, perceived ease of use is influenced by the amount of information. Furthermore, the majority of respondents prefer to have projects such as mosques, Islamic boarding schools, schools, and hospital construction projects. To increase user acceptance, online waqf developers should provide more information about the application process and develop more user-friendly software with many features. Moreover, regulators should provide incentives for online waqf developers to maximise cash waqf collection.
Exploratory research in the creation of mono-structured low-combustibility fibreboards
Authors: Леонович А.А. , Свиридо Е.А. , Глазунова М.Г. 
Published: November 2020

Антипирен на основе гидроксиэтилидендифосфоновой кислоты вводили в древесное волокно (смесь березы и осины), массу обрабатывали меламинокарбамидоформальдегидным связующим, формировали ковер и прессовали огнезащищенные древесноволокнистые плиты средней плотности. С использованием экспериментально-статистических моделей изучали влияние продолжительности прессования, содержания антипирена и связующего на свойства плит по показателям прочности при изгибе, модулю упругости, набуханию и горючести. Проведен анализ и показана на уровне требований стандартов возможность изготовления плит общего назначения или конструкционных пониженной горючести путем варьирования в установленных пределах рецептурными и технологическими факторами.
A fire retardant based on hydroxyethylidene diphosphonic acid was introduced into wood fiber (a mixture of birch and aspen), the mass was treated with a melaminecarbamide-formaldehyde binder, a carpet was formed, and fire-resistant mediumdensity fiberboards were pressed. Using experimental statistical models, we studied the effect of pressing duration, fire retardant and binder content on the properties of plates in terms of flexural strength, modulus of elasticity, swelling and flammability. The analysis is carried out and the possibility of manufacturing plates of general purpose or structural low combustibility by varying prescription and technological factors within the established limits is shown at the level of standards requirements.
Morphological and molecular characterization of Epidorylaimus procerus sp. n. (Dorylaimida: Qudsianematidae) from Vietnam
Authors: Nguyen Thi Anh Duong , Peña-Santiago Reyes 
Published: November 2020

Abstract

Epidorylaimus procerus sp. n., collected from a natural habitat in Vietnam, is described and illustrated. It is distinguishable by its 2.16 to 2.46-mm-long body, lip region offset by depression and 15 to 17-µm broad, odontostyle 32 to 35-µm long, neck 415 to 461-µm long, pharyngeal expansion occupying 47 to 52% of the total neck length, uterus 76 to 130-µm long or 1.0 to 1.5-body diameters, vulva transverse (V = 40-43), caudal region conical elongate (157-186 µm, c =12.1-14.4, c′ = 4.4-5.5) with blister-like bodies, and hyaline portion occupying one-fourth its length, and males absent. Molecular analysis shows a close relationship of the new species and E. lugdunensis, supporting monophyly of the genus Epidorylaimus.
Urban water supply automation – today and tomorrow
Authors: Olsson Gustaf 
Published: November 2020

AbstractAutomation is a collection of a whole set of theories and methods to make a system work automatically as intended, in our case the urban water supply system. A critical feature of automation is the feedback principle: a sensor is measuring a certain variable, e.g. a concentration; a computer tests that the measurement is valid; a computer algorithm calculates and decides what should be corrected; a pump or valve or some other device transforms the decision to action. All of this is untouched by human hand. The ‘intention’, or the goal, must be provided to the controller. The key component of automation is the system that can represent any component or process in the water supply system and even the complete system. Automation technology always must be combined with a true understanding of people at all levels. Otherwise, there is a high risk for misunderstandings and failures. Three categories of problems are highlighted, where automation can contribute: uncertainty, feedback, and complexity. A key challenge is the handling of disturbances. Integrated management of the whole urban water cycle will be required in future urban areas to acquire sustainable operations. Automation is a crucial condition to make integration possible in complex systems.
Chlorpyrifos remediation in agriculture runoff with homogeneous solar photo-Fenton reaction at near neutral pH: phytotoxicity assessment
Authors: Naddafi Kazem , Martinez Susana Silva , Nabizadeh Ramin , Yaghmaeian Kamyar , Shahtaheri Seyed Jamaleddin , Amiri Hoda 
Published: November 2020

AbstractThis study represents the first application of Fe–citrate-based photo-Fenton chemistry for the degradation of chlorpyrifos (CPF) spiked into agricultural runoff, and its phytotoxicity assessment. The effects of the initial CPF concentration, time and ratio of Fe–citrate/H2O2 on CPF removal during the photo-Fenton reaction were investigated and modeled with analysis of variance using R software by the response-surface methodology package. According to the stationary point in original units, the optimal condition for 70.00% CPF removal was as follows: CPF = 2.5 mg L−1 (0.0), time = 48.0 min (0.585) and Fe–citrate/H2O2 = 0.075 (0.539). Beside running the system at near-neutral pH, another strength of this study is related to the treatment of agricultural runoff contaminated with CPF with a raceway pond reactor, which has the advantages of simplicity of the facilities and procedures, as well as the possibility of using sunlight more efficiently in the field of applications. Finally, untreated and treated agriculture runoffs were used as irrigation to determine their phytotoxic effects on seed germination of cress (Lepidium sativum). Solar photo-Fenton treatment greatly reduced phytotoxicity of agriculture runoff and showed the highest germination percentage (70%) compared to both raw agricultural runoff (60%) and untreated CPF-spiked runoff (35%).
Application of Machine Learning Techniques in Drug-target Interactions Prediction
Authors: Zhang Shengli , Wang Jiesheng , Lin Zhenhui , Liang Yunyun 
Published: November 2020

Background:
Drug-Target interactions are vital for drug design and drug repositioning. However,
traditional lab experiments are both expensive and time-consuming. Various computational methods which applied
machine learning techniques performed efficiently and effectively in the field.

Results:
The machine learning methods can be divided into three categories basically: Supervised methods,
Semi-Supervised methods and Unsupervised methods. We reviewed recent representative methods applying
machine learning techniques of each category in DTIs and summarized a brief list of databases frequently used
in drug discovery. In addition, we compared the advantages and limitations of these methods in each category.

Conclusion:
Every prediction model has both strengths and weaknesses and should be adopted in proper ways.
Three major problems in DTIs prediction including the lack of nonreactive drug-target pairs data sets, over optimistic
results due to the biases and the exploiting of regression models on DTIs prediction should be seriously
considered.