bluuebunny/crossref_metadata_2025_split huggingface dataset:
Skyrmion lattice creep at ultra-low current densities
Authors: Luo Yongkang , Lin Shi-Zeng , Leroux Maxime , Wakeham Nicholas , Fobes David M. , Bauer Eric D. , Betts Jonathan B. , Thompson Joe D. , Migliori Albert , Janoschek Marc , Maiorov Boris 
Published: November 2020

AbstractMagnetic skyrmions are well-suited for encoding information because they are nano-sized, topologically stable, and only require ultra-low critical current densities jc to depin from the underlying atomic lattice. Above jc skyrmions exhibit well-controlled motion, making them prime candidates for race-track memories. In thin films thermally-activated creep motion of isolated skyrmions was observed below jc as predicted by theory. Uncontrolled skyrmion motion is detrimental for race-track memories and is not fully understood. Notably, the creep of skyrmion lattices in bulk materials remains to be explored. Here we show using resonant ultrasound spectroscopy—a probe highly sensitive to the coupling between skyrmion and atomic lattices—that in the prototypical skyrmion lattice material MnSi depinning occurs at $${j}_{c}^{* }$$

j

c

*

that is only 4 percent of jc. Our experiments are in excellent agreement with Anderson-Kim theory for creep and allow us to reveal a new dynamic regime at ultra-low current densities characterized by thermally-activated skyrmion-lattice-creep with important consequences for applications.
Development and validation of a nomogram to predict synchronous lung metastases in patients with ovarian cancer: a large cohort study
Authors: Yuan Yufei , Guo Fanfan , Wang Ruoran , Zhang Yidan , Bai Guiqin 
Published: November 2020

Abstract
Purpose: Lung metastasis is an independent risk factor affecting the prognosis of ovarian cancer patients. We developed and validated a nomogram to predict the risk of synchronous lung metastases in newly diagnosed ovarian cancer patients.
Methods: Data of ovarian cancer patients from the Surveillance, Epidemiology, and Final Results (SEER) database between 2010 and 2015 were retrospectively collected. The model nomogram was built on the basis of logistic regression. The consistency index (C-index) was used to evaluate the discernment of the synchronous lung metastasis nomogram. Calibration plots were drawn to analyze the consistency between the observed probability and predicted probability of synchronous lung metastases. The Kaplan–Meier method was used to estimate overall survival rate, and influencing factors were included in multivariate Cox regression analysis (P&lt;0.05) to determine the independent prognostic factors of synchronous lung metastases.
Results: Overall, 16059 eligible patients were randomly divided into training (n=11242) and validation cohorts (n=4817). AJCC T, N stage, bone metastases, brain metastases, and liver metastases were evaluated as predictors of synchronous lung metastases. Finally, a nomogram was constructed. The nomogram based on independent predictors was calibrated and showed good discriminative ability. Mixed histological types, chemotherapy, and primary site surgery were factors affecting the overall survival of patients with synchronous lung metastases.
Conclusion: The clinical prediction model has high accuracy and can be used to predict lung metastasis risk in newly diagnosed ovarian cancer patients, which can guide the treatment of patients with synchronous lung metastases.
Du bon usage des lignes esthétiques
Authors: Marty Claire , Vergnes Jean-Noël , Lodter Christiane 
Published: November 2020

Introduction : Les lignes esthétiques sont des paramètres céphalométriques de référence proposées dans les années 60 et connues de tous les orthodontistes. Les plus utilisées sont celles de Ricketts, Steiner et Burstone.
Elles formalisent de façon simple l’évaluation du profil labial cutané dans le sens sagittal et déterminent le diagnostic de prochélie, normochélie ou rétrochélie. Cependant, nous pouvons nous interroger sur la pertinence de ces références. L’objectif de cette étude observationnelle transversale est d’évaluer leur légitimité afin de guider le plan de traitement orthodontique et l’indication de repositionnement dentaire selon l’âge du patient.
Matériel et méthode : L’échantillon est composé de 96 patients sans limite d’âge dont les téléradiographies sont sélectionnées par stratification aléatoire. Les trois critères de jugement principaux sont les lignes E de Ricketts, S de Steiner et B de Burstone. Les mesures sont effectuées par un seul opérateur via le logiciel IMAGEJ.
Résultat : D’après l’analyse de Spearman, plus le sujet est âgé, plus la rétrochélie augmente. Ceci avec une forte fiabilité pour les critères de Ricketts (rho>0,6) et Steiner (rho>0,6). De plus, l’âge pivot à 25 ans est vérifié par le test de Wilcoxon-Mann-Whitney (p < 0,05).
Conclusion : L’utilisation des lignes esthétiques E, S et B comme argument d’un repositionnement dentaire chez l’adolescent et l’adulte jeune est injustifiée, de par l’absence de prise en compte du recul labial physiologique avec l’âge.
CANreduce 2.0: Reduzierung des Cannabiskonsums unter Berücksichtigung von psychischen Komorbiditäten wie der Generalisierten Angststörung – Zwei Fliegen auf einen Schlag?
Authors: Malischnig Doris , Baumgartner Christian , Schaub Michael P. 
Published: November 2020

Zusammenfassung
Ziel der Studie Zahlreiche Studien weisen auf ein breites Spektrum häufig gleichzeitig auftretender psychischer Störungen wie jene der Generalisierten Angststörung bei der Behandlung von Personen mit Cannabiskonsumstörungen hin (GAD). Bisherige Internet-basierte Studien konnten zwar vereinzelt die Reduktion von Cannabiskonsum zeigen, berücksichtigten aber keine komorbide Störungen. Ziel des E-Coach gestützten Online-Selbsthilfeprogramm CANreduce 2.0 ist die Reduzierung des Cannabiskonsums und der gegebenenfalls vorhandenen GAD.
Methodik Sekundäranalyse der in der Allgemeinbevölkerung rekrutierten Cannabiskonsumierenden der CANreduce 2.0 Studie der beiden aktiven Interventionsgruppen (N=367). Für die Analysen wurden diese Teilnehmende aufgrund ihres erreichten Symptomatik-Wertes der General Anxiety Disorder Scale (GAD-7) in 4 Gruppen eingeteilt: Minimale (GAD-7 Werte: 0–4; N=102), Milde (5–9; N=151), Moderate (10–14; N=78) und Schwere (15–21; N=36) Angststörung und anschliessend ihre Behandlungsverläufe mittels Intention-to-Treat Analysen bezüglich ihrer Cannabiskonsumtage und ihrer Werte auf dem Cannabis Use Disorder Identification Test (CUDIT), der Severity of Dependence Scale (SDS), der GAD-7, der Center of Epidemiologic Studies of Depression Scale (CES-D) sowie bezüglich ihrer Adhärenz verglichen.
Ergebnisse Alle 4 Gruppen reduzierten unabhängig von ihrer GAD-Symptomatik die Anzahl ihrer Cannabiskonsumtage, ihren CUDIT und SDS Score sowohl 6 Wochen als auch 3 Monate nach der Baselineerhebung. Weiter haben mit Ausnahme von der minimalen GAD-7-Gruppe alle Gruppen eine Reduktion der Angstsymptomatik nach 3 Monaten aufgewiesen. Analog zeigten mit Ausnahme der minimalen GAD-7-Gruppe alle GAD-7-Gruppen eine deutliche Reduktion in der depressiven Symptomatik. Bezüglich der gemessenen Adhärenz zeigten sich keine Unterschiede zwischen den GAD-7-Gruppen.
Schlussfolgerungen CANreduce 2.0 scheint sowohl den Cannabiskonsum, die Ausprägung der Cannabiskonsumstörung bzw. die Cannabisabhängigkeit wie auch eine gegebenenfalls vorhandene GAD-Symptomatik zu reduzieren.
Virtuelle Medizin in der Behandlung von Sucht in den USA, Kanada und darüber hinaus
Authors: Krausz R. Michael , Shams Farhud , Cabanis Maurice 
Published: November 2020

ZusammenfassungInsbesondere während der aktuellen Corona-Pandemie hat der Gebrauch virtueller Lösungen in der Medizin international stark zugenommen. Es gibt eine zunehmende Akzeptanz gerade auch in dem Bereich der hausärztlichen Versorgung, der Behandlung psychischer Störungen und der Abhängigkeitserkrankungen.Die Entwicklung ist international unterschiedlich, v. a, wenn man die USA und Kanada auf der einen Seite und Europa, insbesondere Deutschland, andererseits vergleicht. In Nordamerika hat bei dem Einsatz von moderner Technologie die Einführung von „Electronic Medical Record Systems“ eine dominierende Rolle gespielt. Diese ist insbesondere auf Abrechnung und Dokumentation zu Versicherungszwecken fokussiert. Daneben gibt es zunehmend Apps, die spezifische therapeutische Ansätze zu implementieren helfen. Die Anwendung virtueller Ansätze im Suchtbereich ist begrenzt, aber in Teilen sehr innovativ und auf deutsche Verhältnisse anwendbar. Wie in Europa gibt es auch in Nordamerika nur sehr begrenzte Forschungskapazitäten und prinzipiell Widerstand bei den medizinischen Berufsgruppen bezüglich der Anwendungsmöglichkeiten und der Rolle im Behandlungsprozess. Mehr Kooperation würde international zu einer Beschleunigung der Entwicklung und der Etablierung gemeinsamer Standards beitragen sowie die Behandlungssysteme bedeutend verbessern.
Effects of a Combined Endurance/Strength Training Program on Circulating Irisin Levels in Overweight/Obese Men and Women with Type 2 Diabetes Mellitus
Authors: Brinkmann Christian , Weh-Gray Olivier , Bloch Wilhelm , Brixius Klara , Predel Hans-Georg , Kreutz Thorsten 
Published: November 2020

AbstractIrisin is a promising therapeutic target in patients with type 2 diabetes mellitus (T2DM), as studies have demonstrated that irisin can induce “browning“ of adipocytes and mitigate pro-inflammatory conditions. Sex-specific changes in irisin levels have been reported in a study involving healthy men and women following physical training. The present study aims to analyze the effects of an 8-week training intervention on circulating irisin levels in patients with T2DM and to find out whether the training responses differ between T2DM men and women. Twenty-nine overweight/obese T2DM patients (19 men, 10 women; age: 46–74 years; body mass index >25 kg/m2) participated in a combined moderate-intensity endurance/strength training program (3 times a week). The irisin levels of men and women did not differ significantly. The post-training irisin levels did not differ significantly from the pre-training values, and there was no interaction effect of sex. This study shows no training-induced (sex-specific) changes in circulating irisin levels in T2DM patients. Large-scale studies using other forms of training are needed to fully clarify whether basal irisin levels can be changed in T2DM men and/or women to counteract T2DM.
Epilepsy: Workup and Management in Adults
Authors: O'Dwyer Rebecca 
Published: November 2020

AbstractWhen managing epilepsy, there is a temptation to focus care with respect to the last and the next seizure. However, epilepsy is a multifaceted chronic condition and should be treated as such. Epilepsy comes with many physical risks, psychological effects, and socioeconomic ramifications, demanding a long-term commitment from the treating physician. Patients with epilepsy, compared to other chronically ill patient populations, have a worse quality of life, family function, and less social support. The majority of patients are well controlled on antiseizure drugs. However, approximately one-third will continue to have seizures despite optimized medical management. The primary aim of this article is to explore the long-term management of chronic epilepsy, and to address some of the particular needs of patients with chronic epilepsy.
Status Epilepticus: Work-Up and Management in Adults
Authors: Meziane-Tani Assia , Foreman Brandon , Mizrahi Moshe A. 
Published: November 2020

AbstractStatus epilepticus is one of the most common neurological emergencies and is likely to have increasing prevalence in coming years given an aging “baby boomer” population in the United States. Because status epilepticus is associated with significant morbidity and mortality, identification and treatment are paramount. Care should be taken to exclude nonorganic mimics and infectious and metabolic causes. Status epilepticus can be classified into stages with associated recommendations for escalation in therapy, increasing from push-dose benzodiazepines to continuous anesthetic infusions and other nontraditional therapies. Concurrent electroencephalogram monitoring helps to identify, localize, and assess resolution of ictal patterns alongside antiseizure drug administration. A protocol is proposed for the management of status epilepticus in a step-wise fashion.
A delicate balance
Authors: Reichl Isabella , Kapogianni Eleni 
Published: November 2020

AbstractThis paper examines the factors that influence the outcome of exchanges containing refusals, focusing specifically on the role of irony. For this purpose, we analyse spontaneous conversations in English (SPICE-Ireland Corpus and Spoken BNC) within a discursive framework (Eelen 2001;Mills 2003;Watts 2003) that considers the negotiation of opposing views as well as relationships between interlocutors. We propose a model that relies on the crucial distinction we draw between the ‘positional’ and the ‘interpersonal’ level, pointing at mismatches between the two when it comes to the presence of conflict. We determine the presence and (non-)resolution of interpersonal conflict based on evidence of relational work (Locher and Watts 2008) and show that although there is no fixed trajectory from irony type (Kapogianni 2011,2018) to interpersonal effect, some ironies are more interpersonally risky than others.
Subtitling of ostensible speech acts (OSAs)
Authors: Yaqubi Mojde 
Published: November 2020

Abstract
Persian-English subtitling of Iranian films deals with the challenges of understanding and transferring ostensible speech
acts (OSAs). Both linguistic and cultural variations of these elements in Persian and English are expected to create serious difficulties
for subtitlers. Although few studies with pragmatics approach have been conducted to interpret the meaning of Persian OSAs, they have been
practically ignored in the fields of translation and subtitling. To fill this gap, this study aims to descriptively investigate the
transference of the meaning of 80 Persian OSAs from selected Iranian films. It also analyses perceptions of 106 target text audiences of
subtitled OSAs by examining their level of comprehension of 14 subtitled OSAs and the effective factors on their understandings. Finally
based on the findings emerged from the descriptive and survey analyses, this study proposes a guideline for Persian-English on assisting the
transfer of the intended meaning of OSAs.
Indoor Air Quality in the Uffizi Gallery of Florence: sampling methodology and preliminary results
Authors: Carletti Cristina , Cellai Gianfranco , Sciurpi Fabio , Russo Giuseppe , Schmidt Eike D. 
Published: November 2020

Abstract
In museums, indoor air quality plays a fundamental role in the visitors and staff well-being as well as in the deterioration processes of the exhibit objects. Due to some complaints dealing with poor air quality conditions reported by the occupants, a preliminary survey in some rooms of the Uffizi Gallery in Florence was carried out. To assess indoor temperature, relative humidity, chemical and microbiological pollutants in the museum, a methodology of investigation and evaluation of the results was defined and applied to several rooms of the Gallery. The survey aim is to underline the presence of critical issues in order to determine the pollutant concentration and compare the sampled values with the limits reported in Italian standards, technical regulation and guidelines. The preliminary results can be used to plan a deepen investigation with a more detailed sampling of specific pollutants. In this paper the results regarding a representative room are shown and discussed.
Climate induced deformation of Panel Paintings: experimental observations on interaction between paint layers and thin wooden supports
Authors: Allegretti O , Bontadi J , Dionisi-Vici P 
Published: November 2020

Abstract

This work describes the experimental evidence of the deformation induced on a XVI century panel painting by climate uncontrolled fluctuations and on structural replicas under controlled laboratory conditions. The objects under measurement have a very thin wooden support (6 mm), caused by thinning and cradling of the original artefact during a restoration made at the beginning of the XX century. This kind of artefacts are very susceptible to suffer mechanical damage.

The data of experiments carried out on the panel and in laboratory conditions show a characteristic behavior, similar to bimetallic strip warp and an interaction between hygroscopic asymmetry and mechanical asymmetry, inducing a peculiar stress dynamic in the interface wood-paint layer during climate fluctuations.

In collaboration with the conservators involved in the restoration process, the effect of buffer hygroscopic systems on the warping has been studied.
Assessment of residual effectiveness for Water-Repellent treatments for building stones. Water absorption tests on the monumental complex Cathedral of San Zeno and the Baptistery of San Giovanni in Corte in Pistoia
Authors: Martelli M , Salvatici T , Garzonio C A , De Vita M 
Published: November 2020

Abstract
Preventive and temporal planning of conservation is rather difficult to perform, especially concerning monumental stone buildings; the choices are often made after the degradation phenomena have already started. Many studies are looking for the reasons for this ‘resistance’. In particular the present study, the result of a doctorate research, is focused on the most operational aspects: • quantifying the residual effectiveness of water-repellent protective agents used in past restorations; • providing elements in the drafting of maintenance plans for monumental heritage; • verifying where critical conservation elements reside. The test site has been the monumental complex formed by the Cathedral of San Zeno and the Baptistery of San Giovanni in Corte in Pistoia, where the Contact Sponge Water Absorption Test (UNI 11432:2011), typically used as treated/untreated test was employed on three lithological types (white marble, serpentine and Tuscan grey sandstone) as comparison test between treatments carried out at different knows times. The test campaign was conducted by Mila Martelli with the involvement of Superintendency of Archaeology, Fine Arts and Landscape; University of Florence DiDA, DST-LAM, Department of Chemistry and, in the phase of organization of the monitoring, with the involvement of Dr. Maria Jose’ Ybañez Worboys, art restorer. The results of this research must be read in consideration of the fact that it is an ex-post survey, for which not all factors have been kept under control from the beginning, but for which it was possible to make assumptions. This study illustrates the methods and the first test results obtained which show a rather rapid decline in the effectiveness of water-repellent treatments, already a few years after their application.
Monitoring and Conservation plans for monumental stone buildings. The case study of the Baptistery of San Giovanni in Corte in Pistoia
Authors: Martelli M , Jose’ Ybañez Worboys Maria , Tesi Valerio 
Published: November 2020

Abstract
In preventive conservation of cultural heritage, regrettably, only a few concrete examples of conservation and maintenance plans for monumental assets are available. This is attributable both to the particularity of each case, which makes it difficult to draw up a standard conservation plan and to the difficulty of finding specific data to program the cyclicity of the interventions, which requires us to resort almost exclusively to continuous monitoring of monuments. On the Baptistery of San Giovanni in Corte in Pistoia, after a major restoration carried out on the occasion of the Jubilee of 2000, a series of conservation interventions on various fronts have been repeated from 2000 to today. This case was deemed particularly interesting precisely because of this peculiar palimpsest of documented interventions and has, therefore, become the subject of a doctoral research (conducted in collaboration between the University of Florence and the Superintendency of Archaeology, Fine Arts and Landscape), focused on the in situ evaluation of the durability of water-repellent treatments on stone. Starting from the results already obtained with the tests of 2108, and collected in the doctoral thesis, was organized a monitoring plan of water repellent treatments commonly used on white marble, serpentine and Tuscan grey sandstone. The monitoring data should thus merge into the assessments on which the Monument Conservation Plan is founded. This essay presents the choice of the monitoring plan, the designing of test points, the performed treatments, and the planning of the monitoring; it also shows the expected results and how datasets will converge into the drafting and management of the conservation plan. As a result, the study provides useful promptings for implementing a ‘final scientific report’ and a Conservation Plan and, in general, it deepens knowledge on preventive conservation and contributes to the systematization of data for real usefulness for the maintenance of monuments.
CollectionCare: an affordable service for the preventive conservation monitoring of single cultural artefacts during display, storage, handling and transport
Authors: Perles A , Fuster-López L , García-Diego F J , Peiró-Vitoria A , García-Castillo A M , Andersen C K , Bosco E , Mavrikas E , Pariente T 
Published: November 2020

Abstract
In recent years there has been growing interest in the development of devices and software packages that allow museum decision-makers to manage the environmental conditions in collections and estimate the evolution of degradation of objects. A system able to monitor the environmental conditions but also to provide warnings and recommendations about failure boundaries would optimize conservation actions and strategies thus ensuring proper conservation of the collections in the long term.
CollectionCare project aims to develop an innovative and affordable decision support system for the preventive conservation of cultural objects in small and medium-sized museums by combining research and technological advances in monitoring systems (sensor nodes), wireless communications, cloud computing, big data, and material degradation models.
Validation and demonstration activities for the CollectionCare system will be carried out in six different European museums. To this end, communication efforts will be developed to promote the importance and applicability of these technologies in the conservation of cultural objects. All this in order to increase citizens’ awareness of the importance of preventive approaches for the conservation of the European cultural heritage.