bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does culture shape face perception in autism? Cross‐cultural evidence of the own‐race advantage from the UK and Japan
Authors: Hanley Mary , Riby Deborah M. , Derges Michael‐John , Douligeri Anna , Philyaw Zackary , Ikeda Takahiro , Monden Yukifumi , Shimoizumi Hideo , Yamagata Takanori , Hirai Masahiro 
Published: January 2020

AbstractAutism spectrum disorders (ASD) are associated with face perception atypicalities, and atypical experience with faces has been proposed as an underlying explanation. Studying the own‐race advantage (ORA) for face recognition can reveal the effect of experience on face perception in ASD, although the small number of studies in the area present mixed findings. This study probed the ORA in ASD by comparing two cultural groups simultaneously for the first time. Children with ASD in the UK (N = 16) and Japan (N = 26) were compared with age‐ and ability‐matched typically developing (TD) children in the UK (N = 16) and Japan (N = 26). Participants completed a two‐alternative forced‐choice task, whereby they had to recognize a just seen face from a foil which was manipulated in one of four ways (IC: identity change; EE: easy eyes; HE: hard eyes; HM: hard mouth). Face stimuli were Asian and Caucasian, and thus the same stimuli were own and other race depending on the cultural group. The ASD groups in the UK and Japan did not show impaired face recognition abilities, or impairments with recognizing faces depending on manipulations to the eye region, and importantly they showed an ORA. There was considerable heterogeneity in the presence of the ORA in ASD and TD and also across cultures. Children in Japan had higher accuracy than children in the UK, and TD children in Japan did not show an ORA. This cross‐cultural study challenges the view that atypical experiences with faces lead to a reduced/absent ORA in ASD.
Misdiagnosis of anomalous origin of the left coronary artery from the pulmonary artery by echocardiography: Single‐center experience from China
Authors: Lin Shan , Xie Mingxing , Lv Qing , Wang Jing , He Lin , Wang Bin , Li Yuman , Xu Lingling , Yang Yali 
Published: January 2020

AbstractObjectivesTo identify the risk factors causing misdiagnosis by echocardiography and missed diagnosis of anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA).Materials and MethodsEchocardiographic results of 16 patients with ALCAPA confirmed by surgery in Union Hospital, Wuhan, were analyzed retrospectively. The influencing factors leading to echocardiographic misdiagnosis were analyzed from the aspects of confusing image characteristics, special pathological anatomy of the left coronary artery (LCA), and operators' working years.ResultsEchocardiography diagnosed 11 cases with an accuracy rate of 68.8%. Five cases were misdiagnosed, three cases as endocardial fibroelastosis, one case as mitral prolapse with severe insufficiency, and one case as coronary‐pulmonary artery fistula. Display rate of the specific echocardiographic features for confirmed group and misdiagnosed group was statistically significantly different（P = .014）. But the working years of the operator for confirmed group and misdiagnosed group were not statistically significantly different（P = .267）. Some special pathological anatomy and pathophysiological features could be also the cause of misdiagnosis.ConclusionsEchocardiography is the first diagnostic choice of the ALCAPA in China. It is essential for the operator to have the knowledge, diagnostic awareness, and proficiency in manipulation in the accurate interpretation of echocardiography results.
Noncoronary sinus of Valsalva aneurysm resembling a cystic cardiac mass
Authors: Sonsoz Mehmet Rasih , Yılmaz Mustafa , Bugra Zehra 
Published: January 2020

AbstractA sinus of Valsalva aneurysm is a rare cardiac anomaly, and it is usually clinically silent. However, it may lead to symptoms when it compresses adjacent cardiac structures. Herein, we would like to report a 45‐year‐old lady with exertional dyspnea who was first diagnosed with having a cystic cardiac mass on transthoracic echocardiogram. Then, transesophageal echocardiogram and cardiac computed tomography revealed an unruptured aneurysm of noncoronary sinus of Valsalva.
Nasopalatine canal and periapical radiolucency fusion following dentoalveolar trauma: A CBCT‐based case‐control study
Authors: Jacobs Reinhilde , Shujaat Sohaib , Salvo Natalia , Bornstein Michael M. , Politis Constantinus 
Published: January 2020

AbstractBackground/AimThere is a lack of evidence regarding the radiological characteristics of a periapical radiolucency (PRL) fusion with the nasopalatine canal (NPC) following dentoalveolar trauma. The aim of this study was to assess the NPC enlargement resulting from fusion with a PRL and its relationship with the surrounding anatomical structures.Material and methodsA total of 100 patients was retrospectively recruited and divided into two groups: case group and control group. The case group consisted of 50 cone‐beam computed tomography scans of the maxilla of patients (32 males, 18 females; age range: 11‐83 years) with a known history of dentoalveolar trauma in the maxillary anterior region and the presence of an undiagnosed and/or asymptomatic NPC and PRL fusion. An age‐ and gender‐matched control group of 50 patients (32 males, 18 females; age range: 11‐82 years) without trauma history to the upper anterior teeth, demonstrating normal maxillary scans, was recruited. A subjective scoring criterion was established for assessing the characteristics of the fused lesion and its relationship with the buccal/palatal alveolar cortex, nasal cavity cortex, NPC cortical border, and maxillary sinus floor.ResultsThe fused NPC and PRL was mainly lobular in appearance (88%) with non‐corticated well‐defined margins (80%). Male patients showed larger (68%) dimensions compared with female patients (32%). The NPC cortical bone was the most commonly perforated structure in relation to fusion (72%), whereas maxillary sinus cortical bone was the least effected (2%). A statistically significant difference was observed between the NPC dimensions in the control and test groups, with fused lesions having larger mesiolateral, craniocaudal, and buccopalatal dimensions (P < .001).ConclusionsPeriapical radiolucencies should be treated as soon as possible before they fuse with NPC. In case of fusion, surgical enucleation should be considered as the treatment of choice.
Evaluation of student‐to‐student local anaesthesia administration at the University of Barcelona: A cross‐sectional study
Authors: Sánchez‐Garcés Mª Ángeles , Arnabat‐Domínguez Josep , Camps‐Font Octavi , Toledano‐Serrabona Jorge , Guijarro‐Baude Aina , Gay‐Escoda Cosme 
Published: January 2020

AbstractIntroductionTo determine changes in anxiety perceived in students during their first experience injecting local anaesthetic and assess the variability in the perception in the teaching/learning experience as surgeons and patients in relation to gender.Material and methodsThis cross‐sectional study was carried out on students enrolled in the Anaesthesia and Resuscitation course at the University of Barcelona. A descriptive and bivariate analysis was carried out using McNemar and Fisher tests. The level of significance was set at a P‐value of <.05.ResultsOut of 85 students, a total of 71 responses were obtained. Overall, significant anxiety changes associated with the inferior alveolar nerve block were observed, specifically, before and during (P = .003), before and after (P < .001), and during and after (P < .001) the injection. The calm/relaxed category showed significant differences between before and after (P < .001) and during and after (P < .001) the procedure. Opinions and responses from male and female students differed statistically in relation to the injection on each other as preparation for real work situations (P < .023), recognition of landmarks (P < .001), determination of the insertion points (P = .032) and the need for supervision (P = .043).ConclusionsThis study showed that the overall, students felt more anxious before being injecting with the anaesthetic and the students learning to give the local anaesthetic to each other is an appropriate learning method. No gender‐related differences were observed in the participants.
Cav2.1 C‐terminal fragments produced in Xenopus laevis oocytes do not modify the channel expression and functional properties
Authors: Ménard Claudine , Charnet Pierre , Rousset Matthieu , Vignes Michel , Cens Thierry 
Published: January 2020

AbstractThe sequence and genomic organization of the CACNA1A gene that encodes the Cav2.1 subunit of both P and Q‐type Ca2+ channels are well conserved in mammals. In human, rat and mouse CACNA1A, the use of an alternative acceptor site at the exon 46–47 boundary results in the expression of a long Cav2.1 splice variant. In transfected cells, the long isoform of human Cav2.1 produces a C‐terminal fragment, but it is not known whether this fragment affects Cav2.1 expression or functional properties. Here, we cloned the long isoform of rat Cav2.1 (Cav2.1(e47)) and identified a novel variant with a shorter C‐terminus (Cav2.1(e47s)) that differs from those previously described in the rat and mouse. When expressed in Xenopus laevis oocytes, Cav2.1(e47) and Cav2.1(e47s) displayed similar functional properties as the short isoform (Cav2.1). We show that Cav2.1 isoforms produced short (CT1) and long (CT1(e47)) C‐terminal fragments that interacted in vivo with the auxiliary Cavβ4a subunit. Overexpression of the C‐terminal fragments did not affect Cav2.1 expression and functional properties. Furthermore, the functional properties of a Cav2.1 mutant without the C‐terminal Cavβ4 binding domain (Cav2.1ΔCT2) were similar to those of Cav2.1 and were not influenced by the co‐expression of the missing fragments (CT2 or CT2(e47)). Our results exclude a functional role of the C‐terminal fragments in Cav2.1 biophysical properties in an expression system widely used to study this channel.
The rescue effect and inference from isolation–extinction relationships
Authors: Van Schmidt Nathan D. , Beissinger Steven R. 
Published: January 2020

AbstractThe rescue effect in metapopulations hypothesises that less isolated patches are unlikely to go extinct because recolonisation may occur between breeding seasons (‘recolonisation rescue’), or immigrants may sufficiently bolster population size to prevent extinction altogether (‘demographic rescue’). These mechanisms have rarely been demonstrated directly, and most evidence of the rescue effect is from relationships between isolation and extinction. We determined the frequency of recolonisation rescue for metapopulations of black rails (Laterallus jamaicensis) and Virginia rails (Rallus limicola) from occupancy surveys conducted during and between breeding seasons, and assessed the reliability of inferences about the occurrence of rescue drawn from isolation–extinction relationships, including autologistic isolation measures that corrected for unsurveyed patches and imperfect detection. Recolonisation rescue occurred at expected rates, but was elevated during periods of disturbance that resulted in non‐equilibrium metapopulation dynamics. Inferences from extinction–isolation relationships were unreliable, particularly for autologistic measures and for the more vagile Virginia rail.
Audiogenic seizure as a model of sudden death in epilepsy: A comparative study between four inbred mouse strains from early life to adulthood
Authors: Martin Benoît , Dieuset Gabriel , Pawluski Jodi L. , Costet Nathalie , Biraben Arnaud 
Published: January 2020

AbstractObjectiveMouse models of sudden unexpected death in epileptic patients (SUDEP) using audiogenic seizures (AGS) are valuable because death can occur following a sound‐induced seizure in the absence of any pharmacologic or electric component. However, only a few strains of mice are AGS prone, and the vast majority of studies involve DBA/2 or DBA/1 inbred strains. With the goal of characterizing the variation of AGS susceptibility with age, and of offering a larger panel of mice available for AGS studies, we performed a comparative study of the variability in AGS responses.MethodsThe variation of AGS with age was determined in two classically used inbred strains of mice, DBA/2 and DBA/1, and two additional strains, BALB/c and 129/SvTer. As AGS‐stimulated tonic seizures can be lethal or nonlethal, even in the same inbred strain, in a second experiment, we addressed whether there is an innate capacity to reproduce the same response after a tonic AGS, referred to as “determinism,” in the DBA/2J, DBA/1J, and 129/SvTer mouse strains.ResultsResults show that the 129/SvTer mouse is a more versatile model of SUDEP due to its wider age range of susceptibility compared to the DBA/2J and DBA/1J mouse strains. In addition, we show that determinism is not consistently evident in DBA/2J and 129/SvTer strains after AGS. Hence, one cannot be certain that a lethal AGS will always be lethal in successive testing after resuscitation and vice versa in these two mouse strains.SignificanceThese studies highlight the phenotypic variability of AGS in different mouse strains, show the value of an additional mouse strain, 129/SvTer, for studies using AGS, and thus provide valuable information for future studies of AGS and SUDEP.
Exacerbation of hepatic cirrhosis may trigger admission for epilepsy and status epilepticus
Authors: Gursky Jonathan M. , Rossi Kyle C. , Jetté Nathalie , Dhamoon Mandip S. 
Published: January 2020

AbstractObjectiveTo determine whether acute exacerbations of cirrhotic liver disease are associated with higher odds of readmission for epilepsy or status epilepticus.MethodsThe New York State Inpatient Database is a statewide dataset containing data on 97% of hospitalizations for New York State. In this retrospective, case‐crossover design study, we used International Classification of Diseases, Ninth Revision, Clinical Modification codes to identify index status epilepticus and epilepsy admissions. The primary exposure was defined as admission due to an acute exacerbation of cirrhotic liver disease. The case‐crossover analysis tested whether exposure to a hepatic exacerbation within progressively longer case periods (14, 30, 60, 90, 120, 150, and 180 days before index admission), compared to control periods 1 year before the case period, was associated with readmission for epilepsy or status epilepticus.ResultsThe odds ratio for subsequent admission for epilepsy after exposure to an acute exacerbation of cirrhotic liver disease was significant in the 30‐day window at 2.072 (95% confidence interval [CI] = 1.095‐3.92,P = .0252) and peaked in the 150‐day window at 2.742 (95% CI = 1.817‐4.137,P < .0001). In the status epilepticus group, all case periods demonstrated significantly elevated odds of subsequent admission following hepatic exacerbation.SignificanceHepatic exacerbations are associated with increased odds for hospital admissions for epilepsy and status epilepticus across several timeframes.
A comparative study of fatigue estimation methods for single‐spot and multispot welds
Authors: Yang Long , Yang Bing , Yang Guangwu , Xiao Shoune , Zhu Tao , Wang Feng 
Published: January 2020

AbstractFatigue life and load data of spot‐welded samples were obtained by performing tensile‐shear fatigue tests on single‐spot‐welded samples, and by collecting published data on tensile‐shear fatigue tests of multispot‐welded samples. Finite element models of the spot‐welded samples were then constructed, and their accuracy was validated by comparing their results with those of static loading tests. Methods to estimate fatigue in spot‐welded joints proposed by Sheppard, Rupp, and Swellam were used to predict the fatigue life of each sample, and their results were compared. The sensitivity of each method to spot‐welding parameters, as well as the arrangement and number of welded spots, was analyzed to obtain their scope of applicability. Finally, the Sheppard and Rupp methods were used to obtain fitted fatigue curves of each spot‐welded sample, and the equivalent life method was used to generate P‐S‐N curves of the single‐spot‐ and multispot‐welded samples. This method can serve as a useful reference for fatigue reliability analyses of mechanical parts with spot‐welded joints.
Child/youth, family and public engagement in paediatric services in high‐income countries: A systematic scoping review
Authors: Gurung Gagan , Richardson Amy , Wyeth Emma , Edmonds Liza , Derrett Sarah 
Published: January 2020

AbstractBackgroundPatient and public engagement in paediatric health‐care decision making is under‐researched, and there is a lack of systematically reviewed literature in this area.ObjectiveTo examine the extent, range and nature of published research investigating the engagement of children/youth, families and the public in paediatric service improvement, to summarize key aspects of the research identified and to identify gaps to help inform future research needs.MethodsLiterature was sought in MEDLINE, EMBASE, PsycINFO and CINAHL. Eligible articles presented research focused on patient, family and public engagement strategies in the paediatric health‐care setting. Two reviewers extracted and charted data and analysed findings using a descriptive numerical summary analysis and a thematic analysis.ResultsFrom 4331 articles, 21 were eligible. Most were from the United States. The majority of studies were undertaken in hospital settings and used quantitative methods. Various patient and public engagement strategies/interventions were examined, including shared decision‐making tools, questionnaires, youth councils/family advisory groups, patient portals and online networks. Most of the studies examined child/youth/parent satisfaction, with fewer investigating treatment outcomes or service improvement. The majority of studies investigated an engagement strategy at the ‘individual treatment’ level of engagement. Regarding the continuum of engagement, most of the studies were at either the ‘consultation’ or ‘involvement’ stage.ConclusionFuture research needs to focus on the investigation of engagement strategies delivered in primary care, and the use of more qualitative and mixed methods approaches is recommended. There is a gap in the area of engagement strategies directed towards ‘service design and resources’ and ‘macro/policy’ levels.
Metronidazole‐loaded glass ionomer dental cements
Authors: Salehi Ghazaleh , Behnamghader Aliasghar , Pazouki Mohamad , Mozafari Masoud 
Published: January 2020

AbstractThe incorporation of antibiotics in glass ionomer cements (GICs) for the treatment of periodontal diseases has been considered as an effective therapeutic strategy. In this research, metronidazole was added to silanized glass fiber‐reinforced GICs. The fiber‐reinforced cements containing antibiotic were made by adding 6.0 w% silanized E‐glass fibers and 3.0 w% metronidazole to the GIC powder. The GIC reinforced with 6.0 w% silanized fibers showed maximum values of 57 MPa, 2.1 GPa, and 1.3 MPa‧m0.5 for the flexural strength, flexural modulus, and fracture toughness, respectively. The release of metronidazole showed a two‐step release in which about 65% of total amount was released in the first 24 hours. Antibacterial test exhibited no bacteria number (CFU/mL) in the presence of GIC containing metronidazole. In addition, gene expression of Streptococcus mutans was performed by real‐time PCR method. Based on PCR results, metronidazole significantly reduced the gtfB and gtfC genes expression, related to adherence and biofilm formation, up to 98% after 7 days in comparison to the control one (P < .001). According to the obtained results, GICs reinforced with silanized fibers containing metronidazole are effective in inhibiting bacteria associated with caries and also acceptable mechanical properties for the development of the next generation of restoration dental materials.
Impact of air classification, with and without micronisation, on the lipid component of rice bran (Oryza sativa L.): a focus on mono‐, di‐ and triacylglycerols
Authors: Spaggiari Marco , Righetti Laura , Folloni Silvia , Ranieri Roberto , Dall'Asta Chiara , Galaverna Gianni 
Published: January 2020

SummaryRice (Oryza sativa L.) bran is an important by‐product produced during the milling of brown rice, rich in several valuable compounds, such as lipids. Moreover, considering the valorisation potential of these material, the application of innovative and low‐impact techniques can improve the overall quality of by‐products for their future exploitation in the food manufacturing. In this study, the impact of air classification and micronisation (fine grinding) of rice bran on the lipid components was studied. These treatments allowed to obtain bran fractions, with different granulometry, from coarse to very fine. The total crude fat content was significantly higher in fine air‐classified rice bran fractions. Besides, polyunsaturated triacylglycerols (TAG) were the most abundant compounds and monoacylglycerols concentration increased from ~15% in rice bran to ~22% in fine fraction. Considering the relevant emulsifying properties of these compounds, this fraction could be used as functional ingredient for the quality improvement of cereal‐based products, without modifying the valuable fatty acid profile.
Polymorphisms in IL‐1A are associated with endometrial cancer susceptibility among Chinese Han population: A case–control study
Authors: Liu Ying , Sun Yao , Wu Jiamin , Xiong Zichao , Du Shuli , Niu Fanglin , Jin Tianbo , Guo Ling 
Published: January 2020

AbstractEndometrial cancer (EC) is one of the most common malignant tumours of the female genital tract, and it has become a serious malignant disease of the female genital tract in China. Existing researches have revealed the association between polymorphisms of IL‐1A and several gynaecological diseases. In this research, we analysed the association between IL‐1A gene polymorphisms and endometrial cancer susceptibility in Chinese female population. A total of 81 patients and 198 healthy people were selected. Odds ratio (OR) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression. Genetic models and analyses showed that IL‐1A rs3783550 TT and rs3783546 CC increased the risk of endometrial cancer under the recessive model, respectively (rs3783550: OR = 2.80, 95%CI: 1.32–5.92, p = .008; rs3783546: OR = 2.79, 95%CI: 1.32–5.89, p = .008). In the recessive model, we also found that both IL‐1A rs1609682 and IL‐1A rs3783521 increased the risk of endometrial cancer, respectively (rs1609682: OR = 2.79, 95%CI: 1.32–5.89, p = .0081; rs3783521: OR = 2.80, 95%CI: 1.32–5.92, p = .008). Haplotype analysis was performed that did not reveal any significant results. In summary, IL‐1A rs3783550, rs3783546, rs1609682 and rs3783521 polymorphisms may be associated with an increased risk of endometrial cancer in Chinese female populations.