bluuebunny/crossref_metadata_2025_split huggingface dataset:
Homeless Adults’ Recovery Experiences in Housing First and Traditional Services Programs in Seven European Countries
Authors: Greenwood Ronni Michelle , Manning Rachel M. , O'Shaughnessy Branagh R. , Vargas‐Moniz Maria J. , Loubière Sandrine , Spinnewijn Freek , Lenzi Michela , Wolf Judith R. , Bokszczanin Anna , Bernad Roberto , Källmén Håkan , Ornelas José ,   the HOME‐EU Consortium Study Group
Published: December 2019

Highlights

Housing First reports more service user recovery but little is known about how this is achieved.

Certain features of homeless services are likely to promote service users’ recovery.

Housing First service users reported more choice, better housing quality, and more satisfaction.

Service features predicted independent housing, psychiatric symptoms, and community integration.

Across socio‐political and economic contexts, Housing First predicts greater recovery than traditional services.
Comparison of extraction methods for recovering ancient microbial DNA from paleofeces
Authors: Hagan Richard W. , Hofman Courtney A. , Hübner Alexander , Reinhard Karl , Schnorr Stephanie , Lewis Cecil M. , Sankaranarayanan Krithivasan , Warinner Christina G. 
Published: December 2019

AbstractObjectivesPaleofeces are valuable to archeologists and evolutionary biologists for their potential to yield health, dietary, and host information. As a rich source of preserved biomolecules from host‐associated microorganisms, they can also provide insights into the recent evolution and changing ecology of the gut microbiome. However, there is currently no standard method for DNA extraction from paleofeces, which combine the dual challenges of complex biological composition and degraded DNA. Due to the scarcity and relatively poor preservation of paleofeces when compared with other archeological remains, it is important to use efficient methods that maximize ancient DNA (aDNA) recovery while also minimizing downstream taxonomic biases.MethodsIn this study, we use shotgun metagenomics to systematically compare the performance of five DNA extraction methods on a set of well‐preserved human and dog paleofeces from Mexico (~1,300 BP).ResultsOur results show that all tested DNA extraction methods yield a consistent microbial taxonomic profile, but that methods optimized for ancient samples recover significantly more DNA.ConclusionsThese results show promise for future studies that seek to explore the evolution of the human gut microbiome by comparing aDNA data with those generated in modern studies.
Study of compatibility between aliphatic polyketone terpolymer and poly(styrene‐r‐acrylonitrile)
Authors: Lee Hong Chan , Son Younggon , Lee Shichoon 
Published: December 2019

ABSTRACTCompatibility studies have been conducted for polyketone (PK) and styrene–acrylonitrile (SAN) blends in which SAN polymers have different acrylonitrile (AN) contents. Measurements of mechanical properties exhibit the immiscibility of PK/SAN blends. Glass transition temperature shifts and width broadening of the glass transition mean partial compatibility in the amorphous region of the PK/SAN blends. Peak shifts of the CO functional group are larger for PK/SAN48 than that of PK/SAN40 blend. In morphological observations, the dispersed domains appear more refined for the PK/SAN48 blend and the PK/SAN48 blend has better boundary adhesion between the two phases. The Flory–Huggins interaction parameters simulated for the PK/SAN mixture were at a low level and the PK/SAN48 blend showed lower values than the PK/SAN40 blend. This means that the PK/SAN polymer blend is partially compatible in the amorphous region. The level of compatibility tends to increase as the AN content of the SAN polymer increases. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48743.
Controlled aggregation of amphiphilic aggregation‐induced emission polycation and superparamagnetic iron oxide nanoparticles as fluorescence/magnetic resonance imaging probes
Authors: Fu Shengxiang , Cai Zhongyuan , Liu Li , Yang Li , Jin Rongrong , Lu Zhiyun , Ai Hua 
Published: December 2019

ABSTRACTFluorescence/magnetic resonance (MR) dual‐mode imaging, which combines the excellent single‐cell sensitivity of fluorescence imaging and the high spatial resolution of MR imaging, has been applied to different biomedical applications. However, the aggregation‐caused quenching characteristic of most fluorescence molecules often put limits in their applications. Herein, a fluorescence/MR dual‐mode imaging probe [polyethylene glycol‐polyethylenimine‐tetraphenylethene (PEG‐PEI‐TPE)/superparamagnetic iron oxide (SPIO)] with aggregation‐induced emission characteristic is prepared by coupling poly(acrylic acid)‐coated SPIO with PEG‐PEI‐TPE. The fluorescence intensity and lifetime of PEG‐PEI‐TPE/SPIO is higher than PEG‐PEI‐TPE especially at lower polymer concentrations (≤0.2 mg mL−1). Moreover, the fluorescence intensity of PEG‐PEI‐TPE/SPIO gradually increased along with the decline of the pH from 9.0 to 4.0, which is beneficial for studying intracellular organelles. The T2 relaxivity of PEG‐PEI‐TPE/SPIO is 212.3 Fe mM−1 s−1 under a 3.0 T MR scanner. Cell labeling experiment shows that PEG‐PEI‐TPE/SPIO can effectively label RAW 264.7 and Hela cells, and labeled cells are visible under both fluorescence and clinical MR examinations. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48760.
Role of Chondrocytes in the Development of Rheumatoid Arthritis Via Transmembrane Protein 147–MediatedNF‐κB Activation
Authors: Ota Mitsutoshi , Tanaka Yuki , Nakagawa Ikuma , Jiang Jing‐Jing , Arima Yasunobu , Kamimura Daisuke , Onodera Tomohiro , Iwasaki Norimasa , Murakami Masaaki 
Published: December 2019

ObjectiveWe have previously reported that the coactivation ofNF‐κB andSTAT3 in nonimmune cells, including synovial fibroblasts, enhances the expression ofNF‐κB target genes and plays a role in chronic inflammation and rheumatoid arthritis (RA). This study was undertaken to examine the role ofNF‐κB activation in chondrocytes and better understand the pathogenesis ofRA. Furthermore, transmembrane protein 147 (TMEM147) was investigated as a representativeNF‐κB activator in chondrocytes.MethodsClinical samples fromRApatients were analyzed by immunohistochemistry. Specimens obtained from patients with polydactyly were used as control samples. The functional contribution of chondrocytes andTMEM147 to arthritis was examined in several murine models ofRA. In vitro experiments (quantitative polymerase chain reaction,RNAinterference, immunoprecipitation, and confocal microscopy) were performed to investigate the mechanism of action ofTMEM147 in chondrocytes.ResultsSamples obtained fromRApatients and mouse models of RA showed coactivation ofNF‐κB andSTAT3 in chondrocytes (P< 0.001). This coactivation induced a synergistic expression ofNF‐κB targets in vitro (P< 0.01). Chondrocyte‐specific deletion ofSTAT3 significantly suppressed the development of cytokine‐inducedRA(P< 0.01).TMEM147 was highly expressed in chondrocytes fromRApatient samples and the mouse models of RA. Gene silencing ofTMEM147 or anti‐TMEM147 antibody treatment inhibited the cytokine‐mediated activation ofNF‐κB in vitro (P< 0.01) and suppressed cytokine‐inducedRAin vivo (P< 0.01). Mechanistically,TMEM147 molecules acted as scaffold proteins for theNF‐κB complex, which included breakpoint cluster region and casein kinase 2, and enhancedNF‐κB activity.ConclusionThese results suggest that chondrocytes play a role in the development ofRAviaTMEM147‐mediatedNF‐κB activation and indicate a novel therapeutic strategy forRA.
Untersuchung des Einflusses der Geometrie von PCM‐Elementen auf ihre Wärmespeichereffizienz
Authors: Musiał Michał 
Published: December 2019

AbstractDer Aufsatz präsentiert die Ergebnisse experimenteller Untersuchungen an Innen‐Fensterläden, die durch Phasenwechselmaterialien (Phase Change Material – PCM) modifiziert wurden. Gegenstand der Analyse ist die Beurteilung der Erhöhung der Wärmekapazität von Jalousien als Maßnahme zur Energieeinsparung. Eine Erhöhung der Wärmekapazität von Jalousien wurde durch die Verwendung von organischem Wechselphasen‐Material erzielt. Diese Materialien sind relativ teuer, sodass ihre effektivste Verwendung darin besteht, mit geringem finanziellem Aufwand einen größtmöglichen energetischen Nutzen zu erzielen. Forschungsergebnisse zeigen, dass Jalousien mit PCM eine bessere Ausnutzung der solaren Gewinne aus Sonneneinstrahlung im Wärmebedarfsprofil ermöglichen. Sie ermöglichen die vorübergehende Speicherung der absorbierten Wärme und reduzieren die täglichen Temperaturschwankungen aufgrund der Verglasung und den Heizwärmebedarf. Die Ergebnisse zeigen eine größere Abhängigkeit der Wärmeverteilung innerhalb von PCM‐Profilen von ihrer Geometrie als von den äußeren Klimabedingungen.
Negative misconceptions about disaster behaviour through availability cascades: An examination of secondhand information and the moderating effect of trait anxiety on disaster myths
Authors: Nogami Tatsuya 
Published: December 2019

AbstractThe present study was designed to shed light on the origin of disaster myths, such as panic, looting, crime, and psychological shock in postdisaster situations, by examining effects of secondhand information and the moderating effect of anxiety on such negative misconceptions. It was hypothesized that secondhand information on disaster behaviour, such as media reports and word‐of‐mouth rumours, and trait anxiety would increase the degrees to which people gave credit to four popular disaster myths. Also, trait anxiety was predicted to moderate the association between information sources and disaster myths. Questionnaire data obtained from 1,500 Japanese participants indicated that people relying on secondhand information gave more credit to all the four misconceptions than those relying on firsthand information such as direct disaster experience. However, trait anxiety was not found to significantly affect the degrees of the disaster myths. Furthermore, the moderating effect of trait anxiety on the association between the information sources and the disaster myths was not observed in any of the four myths. The present results imply that although reliance on secondhand information increases the degree of disaster myths to some extent, there should be other causes from which disaster myths originate.
Implantation of one versus two MitraClips in the German TRAMI registry: Is more always better?
Authors: Puls Miriam , Huenlich Mark , Boekstegers Peter , Lubos Edith , von Bardeleben Ralph S. , May Andreas E. , Nickenig Georg , Baldus Stefan , Sievert Horst , Ouarrak Taoufik , Senges Jochen , Schillinger Wolfgang 
Published: December 2019

AbstractObjectivesTo compare baseline characteristics and outcomes in patients treated with either 1 or 2 MitraClips in the German TRAMI (Transcatheter Mitral Valve Interventions) registry.BackgroundThe MitraClip community seems to silently assume that results should intrinsically be better after implantation of more than one clip, although data is still sparse.MethodsIn 2010–2013, 803 patients were enrolled prospectively into TRAMI (461 one‐clip and 312 two‐clip procedures). Follow‐up was performed centrally at 30 days and 1 year.ResultsBaseline characteristics of TRAMI‐patients with two clips differed significantly from single‐clip patients regarding constitutional (more men, taller body height) and heart failure‐related factors (larger left ventricular dimensions, reduced left ventricular ejection fraction, more severe heart failure). Also, a significant increase in two‐clip procedures over time was present.After propensity score matching for differing baseline characteristics, residual moderate mitral regurgitation (MR) occurred more frequently after implantation of two clips, whereas residual severe MR could more frequently be observed after one‐clip procedures. However, no or mild residual MR at discharge was present in 71.6% after single‐clip and in 70.1% after two‐clips implantation (p = .81).After 1 year, no significant differences regarding mortality or New York Heart Association status could be detected in the propensity matched cohorts. However, TRAMI‐patients treated with two clips had a significantly higher incidence of cerebral‐vascular events (p = .02).ConclusionsTRAMI data cannot support the theory that implantation of more than one clip is associated with better clinical outcomes. The finding of more cerebral‐vascular events after two‐clip procedures might be hypothesis‐generating.
Mass Loading‐Independent Energy Storage with Reduced Graphene Oxide and Carbon Fiber
Authors: Huang Yuanyuan , Shen Caiwei , Tang Zirong , Shi Tielin , Zheng Sunxiang , Lin Liwei 
Published: December 2019

AbstractLarge‐scale manufacturing of thick electrode films with high energy storage is critical for practical applications. Two‐dimensional materials are promising candidates due to their high surface areas to volume ratios. However, various studies have reported that the storage capacity of these two‐dimensional materials is highly dependent on the thickness of the films. Here, we demonstrate a scheme based on the reduced graphene oxide/carbon fiber composites as supercapacitor electrodes which demonstrate a mass loadings‐independent energy and power performances. Randomly oriented and interconnected carbon fibers are utilized to provide a framework to alleviate the restacking issues of reduced graphene oxide nanosheets and promoting ion flows in the networks. High capacitances maintain even the mass loadings up to 4 mg cm−2. An all‐solid symmetrical supercapacitor has been fabricated to power a LED light and also can power a commercial gas sensor, which shows the practical application potential.
Inflammatory and cardiovascular diseases biomarkers in chronic hepatitis C virus infection: A review
Authors: Babiker Ahmed , Hassan Mohamed , Muhammed Safwan , Taylor Gregory , Poonia Bhawna , Shah Anoop , Bagchi Shashwatee 
Published: December 2019

AbstractHepatitis C virus (HCV) infects 180 million people worldwide and over 4 million people in the United States. HCV infection is a major cause of chronic liver disease and is recognized as a risk factor for clinical cardiovascular disease (CVD). Many studies have shown increased prevalence of cardiac and inflammatory biomarkers in patients with chronic HCV infection (CHC), and though these markers may be used to risk stratify people for cardiac disease in the general population their role in the HCV population is unknown. Patients with CHC have elevated cardiac and inflammatory biomarkers compared to noninfected controls which may play a role in CVD risk stratification. We undertook a systematic review of inflammatory and cardiac biomarkers in people with HCV infection with a focus on the effect of CHC on serum levels of these markers and their utility as predictors of CVD in this population. Medline, EMBASE, and Cochrane databases were searched for relevant articles until June 2019. A total of 2430 results were reviewed with 115 studies included. Our review revealed that HCV infection significantly alters serum levels of markers of inflammation, endothelial function, and cardiac dysfunction prior to HCV treatment, and some of which may change in response to HCV therapy. Current risk stratification tools for development of CVD in the general population may not account for the increased inflammatory markers that appear to be elevated among HCV‐infected patients contributing to increased CVD risk.
Hippocampal oscillatory dynamics and sleep atonia are altered in an animal model of fibromyalgia: Implications in the search for biomarkers
Authors: Blasco‐Serra Arantxa , Alfosea‐Cuadrado Gloria , Cervera‐Ferri Ana , González‐Soler Eva M. , Lloret Ana , Martínez‐Ricós Joana , Teruel‐Martí Vicent , Valverde‐Navarro Alfonso A. 
Published: December 2019

AbstractThe pathogenesis of fibromyalgia is still unknown. Core symptoms include pain, depression, and sleep disturbances with high comorbidity, suggesting alterations in the monoaminergic system as a common origin of this disease. The reserpine‐induced myalgia (RIM) model lowers pain thresholds and produces depressive‐like symptoms. The present work aims to evaluate temporal dynamics in the oscillatory profiles and motor activity during sleep in this model and to evaluate if the model mimics the sleep disorders that occur in fibromyalgia patients. Hippocampal and electromyogram activity were recorded in chronically implanted rats. Following 3 days of basal recordings, reserpine was administered on three consecutive days to achieve the RIM. Postreserpine recordings were taken on alternate days for 21 days. Reserpine induced changes in the sleep architecture with more transitions between states, and a different pattern between the administration period and postreserpine weeks. Administration days were characterized by a larger amount of rapid eyes movement sleep with dominant theta waves without atonia. Following the reserpinization, theta oscillations were always more fragmented and with lower frequency. On the postreserpine days, sleep was dominated by slow‐wave sleep with fast intrusions and reduced hierarchical coupling with spindles and ripples. Simultaneous electromyography recordings also showed muscle twitches during sleep and the dissociation of theta activity and muscle atonia. Abnormally high slow waves, alpha/delta intrusions, frequent transitions, and muscle twitches are common traits in fibromyalgia. Therefore, our analyses support the validity of the RIM model to study sleep disorders in fibromyalgia, and provide new insights into the research of oscillographic biomarkers.
A Nitrogen‐Doped Manganese Oxide Nanoparticles/Porous Carbon Nanosheets Hybrid Material: A High‐Performance Anode for Lithium Ion Batteries
Authors: Zheng Zhong , Li Teng , Wang Ruizi , Tong Zhiqiang , Tian Di , Yuan Liangjie 
Published: December 2019

AbstractA nitrogen‐doped MnO nanoparticles/ porous carbon nanosheets (N−MnO/PCS) composite was synthesized by the room‐temperature redox reaction between KMnO4 and PCS followed by a facile carbothermal reduction, and a subsequent coating process of urea onto MnO/PCS and heat treatment. N−MnO nanoparticles with a grain size of about 30 nm are homogenously embedded on the surface of the N−PCS, corresponding to a high loading of 50.09 wt.% in the resulting composite. Benefiting from the enhanced reaction kinetics as well as electrical conductivity and continuous transport pathways of Li+/electron resulting from the N‐doping and hybridization of the cross‐linked porous carbon substrate, the as‐synthesized N−MnO/PCS‐1 electrode delivers a large reversible specific capacity (1497.2 mA h g−1 at 100 mA g−1 after 160 cycles), outstanding rate capacities (710.6 mA h g−1 at 1 A g−1 and 640.1 mA h g−1 at 2 A g−1) and long‐term cycling stability with specific capacity (976 mA h g−1 at 0.5 A g−1 after cycling 300 cycles). The simple and green synthesis and electronic properties of this composite mean that it has great potential as a high‐capacity anode material for practical application in large‐scale energy storage devices.
Sustainability – A key to Australian finance directors improving their organisation's CSR culture
Authors: Burns Clare Jane M. , Houghton Luke , Stewart Heather 
Published: December 2019

AbstractSustainability, as one of six (economic, ethical, social, stakeholder, sustainability, and discretionary) dimensions of corporate social responsibility (CSR) is frequently espoused in large finance organisations' corporate reports. In this case study on finance board directors, conducted in the lead‐up to the Royal Commission into Misconduct in the Banking, Superannuation and Financial Services Industry (hereafter Commission), sustainability assumptions were not found to be a day‐to‐day consideration for the majority of directors. Directors' primary assumptions, their values‐in‐use, were finance first, followed by risk and defence. Finance, in terms of short‐term profitability, was considered before all espoused values such as customer centricity, integrity, trustworthiness, and professionalism. Within the study there were a small number of directors who did prioritise sustainability, which they closely integrated with the economic (finance) dimension. The additional prioritisation of sustainability led to better integration of the other CSR dimensions and a reduced difference between what is said (espoused) and done. While other CSR and finance studies have focused on “how much”, this study provides unique insights into the “why” of the finance industry's values‐in‐use preceding the 2018 to 2019 Commission which exposed some of the “what” and “when” of director behaviour.
Molecular signaling of G‐protein‐coupled receptor in chronic heart failure and associated complications
Authors: Altamish Mohammad , Samuel Vijaya Paul , Dahiya Rajiv , Singh Yogendra , Deb Pran Kishore , Bakshi Hamid A. , Tambuwala Murtaza M. , Chellappan Dinesh K. , Collet Trudi , Dua Kamal , Gupta Gaurav 
Published: December 2019

AbstractThe well‐known condition of heart failure is a clinical syndrome that results when the myocardium's ability to pump enough blood to meet the body's metabolic needs is impaired. Most of the cardiac activity is maintained by adrenoceptors, are categorized into two main α and β and three distinct subtypes of β receptor: β1‐, β2‐, and β3‐adrenoceptors. The β adrenoreceptor is the main regulatory macro proteins, predominantly available on heart and responsible for down regulatory cardiac signaling. Moreover, the pathological involvement of Angiotensin‐converting enzyme 1 (ACE1)/angiotensin II (Ang II)/angiotensin II type 1 (AT1) axis and beneficial ACE2/Ang (1‐7)/Mas receptor axis also shows protective role via Gi βγ, during heart failure these receptors get desensitized or internalized due to increase in the activity of G‐protein‐coupled receptor kinase 2 (GRK2) and GRK5, responsible for phosphorylation of G‐protein‐mediated down regulatory signaling. Here, we investigate the various clinical and preclinical data that exhibit the molecular mechanism of upset level of GRK change the cardiac activity during failing heart.
Rear negativity: Verbal messages coming from behind are perceived as more negative
Authors: Frankowska Natalia , Parzuchowski Michal , Wojciszke Bogdan , Olszanowski Michal , Winkielman Piotr 
Published: December 2019

AbstractMany studies have explored the evaluative effects of vertical (up/down) or horizontal (left/right) spatial locations. However, little is known about the role of information that comes from the front and back. Basing our investigations on multiple theoretical considerations, we propose that spatial location of sounds is a cue for message valence, such that a message coming from behind is interpreted as more negative than a message presented in front of a listener. Here we show across a variety of manipulations and dependent measures that this effect occurs in the domain of social information. Our data are most compatible with theoretical accounts which propose that social information presented from behind is associated with uncertainty and lack of control, which is amplified in conditions of self‐relevance.
A micrometer head integrated microfluidic device for facile droplet size control and automatic measurement of a droplet size
Authors: Bui Hoang Khang , Seo Tae Seok 
Published: December 2019

AbstractA novel microfluidic droplet generator is proposed, which can control the droplet size through turning an integrated micrometer head with ease, and the size of the produced micro‐droplet can be automatically and real‐time monitored by an open‐sourced software and off‐the‐shelf hardware.