bluuebunny/crossref_metadata_2025_split huggingface dataset:
A dual‐process model of how incorporating audio‐visual sensory cues in video advertising promotes active attention
Authors: Simmonds Lucy , Bogomolova Svetlana , Kennedy Rachel , Nenycz‐Thiel Magda , Bellman Steven 
Published: April 2020

AbstractCapturing consumers’ attention to video advertising is a key marketing challenge. Using real video advertising viewed by a sample of consumers matching the US population on age and gender, the authors examined attention to audio‐visual and visual sensory cues identifying the brand using a biometric measure, phasic heart rate. The findings show differences in attention type depending on which senses are stimulated by the sensory cue. This research uncovers a mechanism (internal processing) for how consumers process multisensory cues (audio‐visual) in video advertising and confirms visual sensory cues can elicit automatic attention through the orienting response. In addition to the dual‐coding explanation for the superiority of audio‐visual sensory cues, the present research suggests a second reason: that audio‐visual sensory cues can elicit additional internal processing of the brand name, resulting in active attention and better storage of the brand in memory. This has implications for the limited capacity model of motivated mediated message processing, as well as for marketers relating to the type of content recommended to follow an audio‐visual or visual sensory cue in video advertising.
A novel non‐invasive wearable sensor for intraocular pressure measurement
Authors: Campigotto Angelica , Lai Yongjun 
Published: April 2020

AbstractGlaucoma is a chronic eye disease where an increase in intraocular pressure (IOP) permanently damaging the optic nerve leading to irreversible vision loss. Intraocular pressure is the main factor for monitoring the progression of glaucoma and has been found to fluctuate throughout the day. A continuous monitoring system can track the fluctuations in the intraocular pressure throughout the day, improving the management of the disease. A novel non‐invasive wearable sensor was created to monitor the fluctuating corneal curvature of the eye and directly relate the deformation to the intraocular pressure. The wearable sensor was able to capture on average 40.8 µm/mmHg with a standard deviation of 29.4 in fluid location per increase in intraocular pressure with an ability to return over 80% back to its original position indicating a good ability to accurately track the fluctuations in the IOP.
Untargeted Metabolomics to Reveal Red versus White Meat–Associated Gut Metabolites in a Prudent and Western Dietary Context
Authors: Goethals Sophie , Rombouts Caroline , Hemeryck Lieselot Y. , Van Meulebroek Lieven , Van Hecke Thomas , Vossen Els , Van Camp John , De Smet Stefaan , Vanhaecke Lynn 
Published: April 2020

ScopeTo improve understanding of the epidemiological link between red and processed meat consumption and chronic diseases, more insight into the formation of metabolites during meat digestion is warranted.Methods and resultsUntargeted mass‐spectrometry‐based metabolomics is applied to explore the impact of red and processed meat consumption (compared to chicken), combined with a prudent or Western dietary pattern. A pig feeding study (n = 32), as a sentinel for humans, is conducted in a 2 × 2 factorial design for 4 weeks. The luminal content of the small intestine and colon are collected to determine their metabolic fingerprints. Seventy‐six metabolites (38 in the small intestine, 32 in the colon, and 6 in both intestinal compartments) contributing to the distinct gut metabolic profiles of pigs fed either chicken or red and processed meat are (tentatively) identified. Consumption of red and processed meat results in higher levels of short‐ and medium‐chain acylcarnitines and 3‐dehydroxycarnitine, irrespective of dietary context, whereas long‐chain acylcarnitines and monoacylglycerols are associated with the red and processed Western diet.ConclusionThe identification of red and processed meat–associated gut metabolites in this study contributes to the understanding of meat digestion in a complex but controlled dietary context and its potential health effects.
Improvement of measuring range in fiber interferometric liquid level sensor by employing digital filter for mode selectivity
Authors: Azmi Asrul Izam , Abdullah Ahmad Sharmi , Mohd Noor Muhammad Yusof , Ibrahim Mohd Haniff , Sheikh Usman Ullah , Raja Ibrahim Raja Kamarulzaman , Tan Tao , Zhang Jianzhong 
Published: April 2020

AbstractA liquid level sensor system based on dual tapers all‐fiber Mach‐Zehnder interferometer incorporating digital filtering is proposed for extended measurement range. Digital filtering technique is employed to selectively isolate beating of a particular dominant cladding mode, resulting a more consistent response in terms of spectra quality and wavelength shift. Sensing characteristics of cladding modes also are studied theoretically and experimentally. From experiment, continuous measurement of water level is demonstrated over 1016‐mm range with sensitivity of −0.0021 nm/mm and R2 of 0.9972. To our knowledge, this is the highest measurement range and linearity for liquid level sensor based on interferometric sensing system has been reported. The proposed technique can be very useful to enhance sensing performance for various fiber interferometric sensor applications.
Factors associated with urinary incontinence in a community sample of young nulligravid women
Authors: Kowalik Casey G. , Daily Adam , Goodridge Sophia D. , Hartigan Siobhan M. , Kaufman Melissa R. , Fowke Jay H. , Dmochowski Roger R. , Reynolds William S. 
Published: April 2020

AbstractAimsThe aim of this study is to identify factors associated with urinary incontinence (UI) in a community sample of young nulligravid women.MethodsThis was a secondary analysis from a cross‐sectional survey‐based study of cisgender women aged 18 to 25 years recruited through a national registry of research volunteers. Participants completed validated questionnaires assessing toileting behaviors, lower urinary tract symptoms (LUTS), and bowel symptoms. Women were excluded from analysis if currently pregnant, any prior pregnancy, cystectomy, or any neurologic disease including spinal cord injury, stroke, or multiple sclerosis. Analyses determined the prevalence of symptoms and evaluated candidate risk factors for UI.ResultsFinal analyses included 964 women (mean age, 22.6 ± 2.0). Monthly UI was identified in 295 (30.6%) subjects, with mixed UI being the most common (56.9%; n = 168). Seventy‐two women (7.4%) reported fecal incontinence (FI) and 24 (3.5%) women reported both UI and FI. After multivariable regression modeling, UI was associated with an intermittent urine stream and the delayed voiding toileting behavior subscale.ConclusionsUI in this cohort of young nulliparous women was highly prevalent and warrants further study as to the cause. Therapeutic guidelines to prevent UI and LUTS may need to be adjusted by targeting populations earlier than traditionally considered.
A minimum time control problem for aerobic degradation processes in biocell composting plants
Authors: Martalò G. , Bianchi C. , Buonomo B. , Chiappini M. , Vespri V. 
Published: April 2020

AbstractWe introduce a mathematical model for the composting process in biocells. The model includes several phenomena, like the aerobic biodegradation of the soluble substrate by means of a bacterial population, the hydrolysis of insoluble substrate, and the biomass decay. We investigate the best strategies to reduce substrate components in minimal time by controlling the effects of cell oxygen concentration on the degradation phenomenon. It is shown that singular controls are not optimal for this model and the optimal control time profiles are of bang or bang‐bang type. The occurrence of switching curves is discussed. In the case of a bang‐bang control we prove that optimal control profiles have a unique switching time and the corresponding switching curve is determined.
Differences in body mass index based on self‐reported versus measured data from women veterans
Authors: Breland Jessica Y. , Joyce Vilija R. , Frayne Susan M. , Phibbs Ciaran 
Published: April 2020

SummaryObjectiveThe objective was to compare differences in body mass index (BMI) calculated with self‐reported versus clinically measured pre‐conception data from women veterans in California.MethodsVeterans Health Administration (VHA) and California state birth certificate data were used to develop a cohort of women who gave birth from 2007–2012 and had VHA data available to calculate BMI (N = 1,326 mothers, 1,473 births). Weighted Kappa statistics assessed concordance between self‐reported and measured BMI. A linear mixed‐effects model with maximum likelihood estimation, adjusted for mother as a random effect, assessed correlates of differences in BMI.ResultsMean BMI was in the overweight range based on self‐reported (26.2 kg/m2, SD: 5.2) and measured (26.8 kg/m2, SD: 5.2) data. Weighted Kappa statistics indicated good agreement between self‐reported and measured BMI (0.73, 95% CI: 0.70, 0.76). Compared to the normal weight group, groups with overweight or obesity were significantly more likely to have lower BMIs when calculated using self‐reported versus measured heights and weights, in unadjusted and adjusted models. The finding was pronounced for class 3 obesity, which was associated with a BMI underestimation of 6.4 kg/m2.ConclusionsEpidemiologic research that guides the clinical care of pregnant women should account for potential under‐estimation of BMI in heavier women, and perform direct measurement where feasible.
Historic herbarium specimens as biocultural assets: An examination of herbarium specimens and their in situ plant communities of the Agulhas National Park, South Africa
Authors: Cowell Carly R. , Anderson Pippin M. L. , Annecke Wendy A. 
Published: April 2020

Abstract

Globally there is a need for protected areas to conserve both biodiversity and heritage. Historic specimen localities, although significant to botanists, are not known or recognized under the global heritage umbrella; yet they form an important component of the protected area landscape.

We aimed to articulate the conservation and heritage value of herbarium specimens, and make the links between people, botanical culture and nature explicit in order to argue the case that historic specimens and their associated in situ plant populations are biocultural heritage assets.

This paper bridges the gap between biodiversity conservation and culture by confirming the presence of historic plant localities in the Cape Floristic Region of South Africa, from collections made prior to 1914.

Once confirmed, present historic plant localities can be included into protected area conservation management and heritage portfolios and ensure a continued contribution to knowledge generation through conservation of these historic sites.

Historic specimens and their associated in situ localities are valuable to both ecological study and conservation around the world and this paper highlights an emerging facet to science of the influence of people on the natural landscape.

We found this to be the case not only in an ecologically transformative way, but from a heritage aspect regarding the social nature of botanizing and discovering.

Historic specimen localities thus link the past with the current and future management of a protected area.

A free Plain Language Summary can be found within the Supporting Information of this article.
Studies on heterocyclic amines based cardanol‐benzoxazine for oil‐water separation
Authors: Hariharan Arumugam , Prabunathan Pichaimani , Manoj Manickam , Alagar Muthukaruppan 
Published: April 2020

AbstractThe present work describes the development of sustainable bio‐benzoxazines for oil water separation and its composites for applications where a low dielectric constant is required. In addition, cardanol benzoxazine monomers (C‐ida and C‐pyta) with low curing temperature were designed with inbuilt catalytic core using two different heterocyclic amines, namely tetra aryl imidazole diamine (ida) and pyridine core triamine (pyta). Cotton fabric coated with poly(C‐ida) and poly(C‐pyta) show water contact angle values of 160° and 164°, respectively. The oil‐water separation efficiency of the polybenzoxazines coated cotton fabrics was 95%. Further, the poly(C‐ida) and poly(C‐pyta) matrices were reinforced with varying weight percentages (1, 3, 5, 7, and 10 wt%) of glycidylpropoxytrimethylsilane‐functionalized biosilica. The benzoxazine matrices and composites obtained were characterized using different analytical techniques in order to assess their molecular structure, cure behavior, thermal stability, morphology, surface, and dielectric behavior. Data obtained from different studies suggest that these matrices and composites can be used as coatings for oil‐water separation and high‐performance micro‐electronics insulation applications under adverse environmental conditions.
Addressing violence against teachers: A social‐ecological analysis of teachers' perspectives
Authors: McMahon Susan D. , Peist Eric , Davis Jacqueline O. , McConnell Elizabeth , Reaves Samantha , Reddy Linda A. , Anderman Eric M. , Espelage Dorothy L. 
Published: April 2020

AbstractMuch research has been dedicated to supporting school communities in combating the problem of school violence. However, violence directed toward teachers is under‐investigated, and knowledge of how to support teachers is limited. This qualitative study used conventional content analysis to assess teachers' recommendations for preventing and improving the response to teacher‐directed violence. The sample included 245 prekindergarten through 12th grade teachers, all of whom experienced school violence and participated in a larger national survey study on violence against teachers. Using a social‐ecological framework and conventional content analysis, teacher recommendations for addressing teacher victimization were identified and organized at the individual, school, community, and society levels. Themes around conflict resolution strategies; improving policies, resources, and relationships with administrators; increasing parental involvement; and changing culture and laws were highlighted. Implications for research, practice, and policy are discussed.
Energetic contributions of amino acid residues and its cross‐talk to delineate ligand‐binding mechanism
Authors: Kumar Sivakumar Prasanth , Patel Chirag N. , Rawal Rakesh M. , Pandya Himanshu A. 
Published: April 2020

AbstractReceptor‐based QSAR approaches can enumerate the energetic contributions of amino acid residues toward ligand binding only when experimental binding affinity is associated. The structural data of protein‐ligand complexes are witnessing a tremendous growth in the Protein Data Bank deposited with a few entries on binding affinity. We present here a new approach to compute the Energetic CONTributions of Amino acid residues and its possible Cross‐Talk (ECONTACT) to study ligand binding using per‐residue energy decomposition, molecular dynamics simulations and rescoring method without the need for experimental binding affinity. This approach recognizes potential cross‐talks among amino acid residues imparting a nonadditive effect to the binding affinity with evidence of correlative motions in the dynamics simulations. The protein‐ligand interaction energies deduced from multiple structures are decomposed into per‐residue energy terms, which are employed as variables to principal component analysis and generated cross‐terms. Out of 16 cross‐talks derived from eight datasets of protein‐ligand systems, the ECONTACT approach is able to associate 10 potential cross‐talks with site‐directed mutagenesis, free energy, and dynamics simulations data strongly. We modeled these key determinants of ligand binding using joint probability density function (jPDF) to identify cross‐talks in protein structures. The top two cross‐talks identified by ECONTACT approach corroborated with the experimental findings. Furthermore, virtual screening exercise using ECONTACT models better discriminated known inhibitors from decoy molecules. This approach proposes the jPDF metric to estimate the probability of observing cross‐talks in any protein‐ligand complex. The source code and related resources to perform ECONTACT modeling is available freely at https://www.gujaratuniversity.ac.in/econtact/.
Output feedback finite‐time stabilization of a class of nonlinear time‐delay systems in the p‐normal form
Authors: Wang Xuhuan , Huang Shipei , Xiang Zhengrong 
Published: April 2020

SummaryThis article investigates the finite‐time output feedback stabilization problem for a class of nonlinear time‐varying delay systems in the p‐normal form. First, a reduced‐order state observer is designed to estimate the unmeasurable state. Then, an output feedback controller is constructed, with the help of the finite‐time Lyapunov stability theorem, it is proved that the state of the resulting closed‐loop system converges to the origin in finite time. Two simulation examples are given to verify the effectiveness of the proposed scheme.
Combined Replenishment of miR‐34a and let‐7b by Targeted Nanoparticles Inhibits Tumor Growth in Neuroblastoma Preclinical Models
Authors: Di Paolo Daniela , Pastorino Fabio , Brignole Chiara , Corrias Maria Valeria , Emionite Laura , Cilli Michele , Tamma Roberto , Priddy Leslie , Amaro Adriana , Ferrari Davide , Marotta Roberto , Ferretti Elisa , Pfeffer Ulrich , Ribatti Domenico , Sementa Angela Rita , Brown David , Ikegaki Naohiko , Shimada Hiroyuki , Ponzoni Mirco , Perri Patrizia 
Published: April 2020

AbstractNeuroblastoma (NB) tumor substantially contributes to childhood cancer mortality. The design of novel drugs targeted to specific molecular alterations becomes mandatory, especially for high‐risk patients burdened by chemoresistant relapse. The dysregulated expression of MYCN, ALK, and LIN28B and the diminished levels of miR‐34a and let‐7b are oncogenic in NB. Due to the ability of miRNA‐mimics to recover the tumor suppression functions of miRNAs underexpressed into cancer cells, safe and efficient nanocarriers selectively targeted to NB cells and tested in clinically relevant mouse models are developed. The technology exploits the nucleic acids negative charges to build coated‐cationic liposomes, then functionalized with antibodies against GD2 receptor. The replenishment of miR‐34a and let‐7b by NB‐targeted nanoparticles, individually and more powerfully in combination, significantly reduces cell division, proliferation, neoangiogenesis, tumor growth and burden, and induces apoptosis in orthotopic xenografts and improves mice survival in pseudometastatic models. These functional effects highlight a cooperative down‐modulation of MYCN and its down‐stream targets, ALK and LIN28B, exerted by miR‐34a and let‐7b that reactivate regulatory networks leading to a favorable therapeutic response. These findings demonstrate a promising therapeutic efficacy of miR‐34a and let‐7b combined replacement and support its clinical application as adjuvant therapy for high‐risk NB patients.
Defects Engineering Leads to Enhanced Photocatalytic H2 Evolution on Graphitic Carbon Nitride–Covalent Organic Framework Nanosheet Composite
Authors: Luo Maolan , Yang Qing , Yang Wenbin , Wang Junhui , He Fangfang , Liu Kewei , Cao Hongmei , Yan Hongjian 
Published: April 2020

AbstractGraphitic carbon nitride nanosheet (CNS) represents an attractive candidate for solar fuel production. However, the abundant defects in CNS lead to serious charge recombination and limit the photocatalytic performance. Herein, the synthesis of a CNS–covalent organic framework (CNS–COF) nanosheet composite is presented for the first time. CNS with significantly reduced defects is first obtained by rationally tuning the thermal exfoliation conditions of bulk carbon nitride. Subsequent modification of the CNS with trace COF nanosheet through chemical imine bonding can not only passivate the surface termination of carbon nitride in the boundary region, but also establish strong electronic coupling between these two components. As a consequence, enhanced charge separation and photocatalytic activity are realized on the resulting CNS–COF nanosheet composite. Under optimum conditions, hydrogen is evolved at a rate of 46.4 mmol g−1 h−1. This corresponds to an apparent quantum efficiency of 31.8% at 425 nm, which is among the best values ever reported for carbon nitride‐based materials.
Inverse changes in raphe and cortical 5‐HT1B receptor availability after acute tryptophan depletion in healthy human subjects
Authors: Baldassarri Stephen R. , Park Eunkyung , Finnema Sjoerd J. , Planeta Beata , Nabulsi Nabeel , Najafzadeh Soheila , Ropchan Jim , Huang Yiyun , Hannestad Jonas , Maloney Kathleen , Bhagwagar Zubin , Carson Richard E. 
Published: April 2020

AbstractSerotonergic neurotransmission plays a key role in the pathophysiology and treatment of various neuropsychiatric diseases. The purpose of this study was to investigate changes in serotonergic neurotransmission after acute tryptophan depletion (ATD) using positron emission tomography (PET) with [11C]P943, a 5‐HT1B receptor radioligand previously shown to be sensitive to changes in 5‐HT. Five healthy subjects were scanned on a high resolution PET scanner twice on the same day, before and approximately 5 hours after ingesting capsules containing an amino acid mixture that lacks tryptophan. For each scan, emission data were acquired for 120 min after intravenous bolus injection of [11C]P943. Binding potential (BPND) values were estimated from parametric images using the second version of the multilinear reference tissue model (MRTM2, t* = 20 min) with cerebellar grey matter used as a reference region. The change in [11C]P943 binding (ΔBPND, %) was calculated as (BPND,post − BPND,pre)/(BPND,pre) × 100, and correlation analysis was performed to measure linear associations of ΔBPND between raphe and other regions of interest (ROIs). ΔBPND ranged from −6% to 45% in the raphe, with positive values indicating reduced competition from 5‐HT. In cortical regions, ΔBPND ranged from −28% to 7%. While these changes did not reach significance, there were significant negative correlations of ΔBPND of the raphe with those of cerebral cortical regions and the thalamus (e.g., r = −.96, p = .011 for average cortex). These findings support the hypothesis that raphe serotonin is a critical modulator of cortical serotonin release via projecting neurons in healthy human subjects.