bluuebunny/crossref_metadata_2025_split huggingface dataset:
Communication frequency between visits is associated with improved glycemic control in pediatric diabetes
Authors: Verma Rohini , Thomas Chrystal G. , West Margaret , Prichett Laura , Glancey Christine , Tracey Julia , Arcara Kristin M. , Magge Sheela N. , Wolf Risa M. 
Published: December 2020

Abstract

Objectives
Children with diabetes are advised to see their diabetes team every 3 months, with interim communication to address insulin dose adjustments. Despite increasing digital accessibility, there is limited data on whether provider–patient communication frequency is associated with glycemic control in pediatric diabetes. We assessed patterns of communication between diabetes clinic visits and whether communication frequency via electronic messaging (EM) and telephone was associated with glycemic control in pediatric diabetes.

Methods
Retrospective chart review of 267 children with type 1 (T1DM) and type 2 diabetes (T2DM) over a 1-year period (July 2018–June 2019) at an urban academic pediatric diabetes center. Association between frequency of communication (via EM and telephone) and HbA1c was analyzed using regression analysis.

Results
Of 267 participants, 224 (84%) had T1DM, 43 (16%) had T2DM, mean age 11.6 years (SD 4), mean duration of diabetes 3.5 years (SD 3.4), and mean HbA1c 73.8 ± 23 mmol/mol (8.9 ± 2.2%). Most participants (82%) communicated with their diabetes team at least once per year, with a mean number of overall communications of 10.3 ± 13.6 times. Communications were via EM (48%), phone (40%), or both (53%). Participants with more frequent communication had lower HbA1c values (p=0.007), even when controlling for age, sex, provider, and number of clinic visits per year. We determined that a threshold of three communications per year was associated with a lower HbA1c (p=0.006).

Conclusions
More frequent communication with the diabetes team between visits is associated with improved glycemic control. Initiatives to contact diabetes patients between clinic visits may impact their overall glycemic control.
Doppler ultrasonography of the uterine artery in correlation with KANET
Authors: Medjedovic Edin , Kurjak Asim 
Published: December 2020

Abstract

Objectives
The aim of this prospective study was to correlate the Doppler ultrasonography of the uterine arteries with the Kurjak Antenatal Neurodevelopmental Test (KANET), to investigate the effect of uterine artery flow assessed by the Doppler on fetal behavior.

Methods
A population of 80 pregnant women in the second trimester of pregnancy was included for uterine artery Doppler (UAD) assessment. The investigation group consisted of 40 women with abnormal UAD, while the control group consisted of 40 women with normal UAD. The inclusion criteria for the investigated group were: gestation above 20 weeks, and an abnormal finding of Doppler ultrasonography of the uterine arteries. All patients underwent a KANET test and were followed up to the end of their pregnancy.

Results
There was a statistically significant difference in the average score of KANET tests between the two groups (9.20±3.32 vs. 13.55±2.21; p=0.001). In the first group, an abnormal flow on the side of the placenta affected the score of the KANET test (B=11.948; p=0.005), while abnormal flow on the opposite side did not affect the score of the KANET test (p>0.05). Physiological flow had no effect on the KANET test in the control group (p>0.05).

Conclusions
Abnormal flow affects the value of the KANET score, and can be used as one of the parameters in evaluation of probable fetal neurodevelopmental disorders.
A multimodal analysis of digitally mediated service encounters using ‘super-sticky’ applications: Implications from the micro to the macro
Authors: de Groot Freek Olaf 
Published: December 2020

Abstract
Digitally mediated service encounters such as digital payments are becoming more common and super-sticky social media such as WeChat, applications which mediate an indispensible part of our day-to-day practices, are increasingly used as the main tool for these services. However, how digital technology affects the way semiotic modes realize lower level actions in service encounters has not widely been studied. This paper carried out a multimodal analysis of videoed service encounters combined with interviews and ethnographic field notes to analyze how the use of WeChat Pay affects how modes such as proxemics, gaze and gesture realize lower level actions such as handing, smartphone handling, and ratifying payments. Second, analyses of the wider semiotic trajectories involved in the use of super-sticky social media in digitally mediated service encounters show how a mundane digital payment has important implications for how we record and disclose our personal behavior in big data and for the distribution of knowledge and skills deploying semiotic resources and digital literacies in society.
Biobleaching: An eco-friendly approach to reduce chemical consumption and pollutants generation
Authors: Kumar Amit 
Published: December 2020

AbstractThe pulp and paper industry is known to be a large contributor to environmental pollution due to the huge consumption of chemicals and energy. Several chemicals including H2SO4, Cl2, ClO2, NaOH, and H2O2are used during the bleaching process. These chemicals react with lignin and carbohydrates to generate a substantial amount of pollutants in bleach effluents. Environmental pressure has compelled the pulp and paper industry to reduce pollutant generation from the bleaching section. Enzymes have emerged as simple, economical, and eco-friendly alternatives for bleaching of pulp. The pretreatment of pulp with enzymes is termed as biobleaching or pre-bleaching. Different microbial enzymes such as xylanases, pectinases, laccases, manganese peroxidases (MnP), and lignin peroxidases are used for biobleaching. Xylanases depolymerize the hemicelluloses precipitated on pulp fiber surfaces and improves the efficiency of bleaching chemicals. Xylanase treatment also increases the pulp fibrillation and reduces the beating time of the pulp. Pectinases hydrolyze pectin available in the pulp fibers and improve the papermaking process. Laccase treatment is found more effective along with mediator molecules (as a laccase-mediator system). Biobleaching of pulp results in the superior quality of pulp along with lower consumption of chlorine-based chemicals and lower generation of adsorbable organic halidesadsorbable organic halides (AOX. An enzyme pretreatment reduces the kappa number of pulp and improves ISO brightness significantly. Better physical strength properties and pulp viscosity have also been observed during biobleaching of pulp.
Bayesian inference for unit root in smooth transition autoregressive models and its application to OECD countries
Authors: Jaiswal Shivam , Chaturvedi Anoop , Bhatti Muhammad Ishaq 
Published: December 2020

Abstract
This paper proposes a Bayesian unit root test for testing a non-stationary random walk of nonlinear exponential smooth transition autoregressive process. It investigates the performance of Bayes estimators and Bayesian unit root test due to its superiority in estimation and power properties than reported in existing literature. The proposed approach is applied to the real effective exchange rates of 10 selected countries of the organization of economic co-operation and development (OECD) and the paper observe some interesting findings which demonstrate the usefulness of the model.
A study of antituberculosis activities and crystal structures of (E)-2-[2-(arylidene)hydrazinyl]pyrimidine and (E)-N
1-(arylidene)pyrimidine-2-carbohydrazide derivatives
Authors: Pinheiro Alessandra C. , Nogueira Thaís C. M. , da Costa Cristiane França , Lourenço Cristina , Low John N. , Wardell James L. , Wardell Solange M. S. V. , de Souza Marcus V. N. 
Published: December 2020

Abstract
A study of the anti-tuberculosis activity against Mycobacterium tuberculosis ATTC 27294 and an X-ray structural determination of (E)-2-[2-(arylidene)hydrazinyl]pyrimidine, 1, and (E)-N
1-(arylidene)pyrimidine-2-carbohydazide, 2, derivatives are presented. The effect of the substituents in the aryl moiety on the antituberculosis (anti-TB) activities of 1 and 2 is compared with that of other heteroaryl hydrazonyl and acylhydrazonyl derivatives. The biological activities of 1 do not depend on the coordinating ability of the substituted aryl group: in 2, the most effective aryl group is 5-nitrofuranyl. The structure determinations of (E)-2-((2-(pyrimidin-2-yl)hydrazono)methyl)-phenol, (E)-N′-(2,5-dihydroxybenzylidene)pyrimidine-2-carbohydrazide and of the hydrate of (E)-N′-(2-hydroxy-4-methylbenzylidene)pyrimidine-2-carbohydrazide, and a literature search of related structures in the CCDC data base, allowed an examination of the more important interactions, including the occurrence of X–Y⋯π interactions.
1-Trifluoromethyl-prop-2-yne 1-iminium salts and 1-imines: reactions with the mesoionic „Nitron“
Authors: Maas Gerhard , Koch Raphael 
Published: December 2020

Abstract
The heterocyclic mesoionic compound (1,4-diphenyl-1H-1,2,4-triazol-4-ium-3-yl)(phenyl)amide („Nitron“) has recently been found to exist in a prototropic equilibrium with minor amounts of a nucleophilic heterocyclic carbene of the 1,2,4-triazolyl-5-ylidene type. Here we report that Nitron reacts with 1-trifluoromethyl-substituted prop-2-yne iminium salts by conjugate nucleophilic addition of the anionic PhN‒ substituent in the mesoionic tautomer, whereas the nucleophilic triazolylidene form is involved in the reaction with 1-CF3-prop-2-yne imines. 3-(2,3-Dihydro-1H-benzo[c]azepin-5-yl)-1H-1,2,4-triazol-4-ium triflate salts were obtained in the former case and (Z)-9-arylidene-1,2,4,7-tetraazaspiro[4.4]nona-2,7-dienes in the latter.
DÜNYADAN VE TÜRKİYE’DEN ÖRNEKLERLE CAM TAVAN SENDROMU
Authors: DERİN Neslihan 
Published: December 2020

Birçok kadın, çalışma hayatında veya yer aldığı çeşitli organizasyonlarda niteliklerinin ve mesleki yeterliliklerinin, erkeklere göre yeterince görülmediğinden, bir çifte standarda tabi tutulduğundan şikayet ederler. Çok sayıda kadın mesleki alanda erkek egemenliğinden dolayı engellenme duygusu yaşar. Bazı kadınlar, kurum çalışanları arasındaki terfi yarışına katılmazlar çünkü en tepeye kadar ulaşamayacaklarını hissederler. Bu durum, kadınlar için, erkekler ve toplum tarafından inşa edilmiş görünmez bir engel “camdan bir tavan” olarak ifade edilir. Bu kavram, toplumsal, örgütsel, kişisel önyargılar ve kalıplar tarafından yaratılan, kadınların üst düzey yönetim pozisyonlarına gelmelerini engelleyen görünmez, yapay engeller olarak tanımlanır. Cam tavan, sadece yükselme ya da hiyerarşik olarak ilerlemeyi içermemektedir. Bu terim, hiyerarşik olarak ilerleme engelinin yanında gelir dağılımındaki adaletsizliği, uygulama, denetim ve üstünlük kullanımındaki eşitsizlikleri de içermektedir.
Bu çalışmanın amacı dünya genelinde konuyla ilgili yapılan araştırmaları inceleyerek “cam tavan” hakkında bir durum analizi yapmaktır. Bu amacı gerçekleştirmek için literatürde konuyla ilgili farklı ülkelerde gerçekleştirilmiş çok sayıda araştırmaya ulaşılmış ve incelenmiştir. Bu incelemelerle, cam tavan sendromunun, kıta, ülke, sektör, kurum gözetmeksizin her yerde var olduğu ve genel olarak benzer nedenlere bağlı olarak ortaya çıktığı sonucuna ulaşılmıştır.
Relation of Driving Under the Influence Laws to Access to Firearms Across US States
Authors: Bowen Andrew G. , Tessler Robert A. , Bowen Deirdre , Haviland Miriam J. , Rowhani-Rahbar Ali , Rivara Frederick P. 
Published: December 2020

Objectives. To determine differences among US states in how driving under the influence of alcohol (DUI) laws activate federal firearm possession and purchase prohibitions. Methods. We performed primary legislative research to characterize DUI laws in each state. The primary outcome was the number of DUI convictions an individual must be convicted of in each state to activate the federal firearm possession and purchase prohibition. We also determined the time interval in which previous DUI convictions count for future proceedings. Results. Forty-seven states had DUI laws that activated the federal prohibition of firearm possession and purchase for a threshold number of repeated DUIs. Variation exists among states in the number of convictions (1–4) and length of liability period (5 years–lifetime) required to prohibit firearm possession and purchase. Conclusions. Variation in state laws on DUI results in differences in determining who is federally prohibited from possessing and purchasing firearms. Future research should explore whether these federal prohibitions arising from DUI convictions are enforced and whether an association exists between stricter DUI policies and reduction in firearm crimes, injuries, and deaths.
Prediction of Survival after Eribulin Chemotherapy for Breast Cancer by Absolute Lymphocyte Counts and Progression Types
Authors: Morisaki Tamami , Kashiwagi Shinichiro , Asano Yuka , Goto Wataru , Takada Koji , Kouhashi Rika , Yabumoto Akimichi , Ishihara Sae , Shibutani Masatsune , Tanaka Hiroaki , Hirakawa Kosei , Ohira Masaichi 
Published: December 2020

Abstract
Background: In the RECIST diagnostic criteria, the concepts of progression by pre-existing disease (PPL) and progression by new metastases (PNM) have been proposed to distinguish between the progression types of cancer refractory to treatment. According to the tumor biology of cancer progression forms, the "PPL" form indicates invasion and the "PNM" form indicates metastasis. On the other hand, recent studies have focused on the clinical importance of inflammatory markers as indicators of the systemic tumor immune response. In particular, absolute lymphocyte counts (ALC) is an indicator of the host’s immune response. Thus, we developed a new measure that combined progression form with ALC. In this study, we clinically validated the combined assessment of progression form and ALC in eribulin chemotherapy.Methods: From August 2011 to April 2019, a total of 486 patients with locally advanced or metastatic breast cancer (MBC) underwent treatment. In this study, only 88 patients who underwent chemotherapy using eribulin were included. The antitumor effect was evaluated based on the RECIST criteria, version 1.1. To measure ALC, peripheral blood samples collected before eribulin treatment were used. The cut-off value for ALC in this study was 1,500 /μL, based on previous studies.Results: The PPL group (71 patients, 80.7%) had significantly longer PFS (p=0.022, log-rank) and OS (p<0.001, log-rank) than the PNM group (17 patients,19.3%). In the 51 patients with ALC <1500/μl, the PPL group had a significantly better prognosis than the PNM group (PFS: p=0.035, OS: p<0.001, log-rank, respectively). On the other hand, in the 37 patients with ALC≥1500/μl, the PPL group had a better OS compared to the PNM group (p=0.055, log-rank), but there was no significant difference in PFS between the two groups (p=0.541, log-rank). Furthermore, multivariate analysis that validated the effect of OS showed that high ORR and “high-ALC and PPL” were factors for a good prognosis (p<0.001, HR=0.321) (p=0.036, HR=0.290).Conclusions: In breast cancer patients with eribulin chemotherapy, good systemic immune status, such as ALC≥1500/μl, was associated with less progression, particularly metastasis, and better prognosis. Furthermore, the biomarker "high-ALC and PPL" was particularly useful as a prognostic marker following eribulin chemotherapy.
Risk Factors for Mortality Among Patients Diagnosed With Multi-Drug Resistant Tuberculosis In Uganda- A Case-Control Study
Authors: Kizito Enock , Musaazi Joseph , Mutesasira Kenneth , Twinomugisha Fred , Namwanje Helen , Kiyemba Timothy , Lopez Debora B. Freitas , Nicholas Nicholas Sebuliba , Nkolo Abel , Birabwa Estella , Dejene Seyoum , Muyanja Stella Zawedde 
Published: December 2020

Abstract
Background:The World Health Organization (WHO) End TB strategy aims to reduce mortality due to tuberculosis (TB) to less than 5% by 2035. However, mortality due to multidrug-resistant tuberculosis (MDR-TB) is particularly high and stood at 15% globally in 2018. In Uganda, MDR-TB associated mortality was 19% in the same year. We set out to examine the risk factors for mortality among a cohort of patients diagnosed with MDR-TB in Uganda.Methods:We conducted a case-control study nested within the national MDR-TB cohort. We defined cases as patient who died from any cause during the two years following treatment initiation. We selected two controls for each case from patients alive and on MDR-TB treatment at the time that the death occurred (incidence-density sampling) and matched the cases and controls on health facility at which they were receiving care. We performed conditional logistic regression to identify the risk factors for mortality. Results:Data from 198 patients (66 cases and 132 controls) started on TB from January 1 to December 31, 2016, was analyzed for this study. Majority of patients (60.6%) were male and were HIV positive (59.6%). About half (46.0%) were aged 19-34 years. On multiple regression analysis, co-infection with HIV (aOR 1.9, 95% CI [1.1-4.92]p=0.05); non-adherence to TB treatment (aOR 1.92, 95% CI [1.02-4.83] p=0.04); age over 50 years (aOR 3.04, 95% CI [1.13-8.20] p=0.03); and not having any education (aOR 3.61, 95% CI [1.1-10.4] p=0.03) were associated with MDR TB mortality. Conclusion: To improve MDR-TB treatment outcomes, to attention must be paid to provision of social support particularly for older persons on MDR TB treatment. Interventions that support treatment adherence and promote early detection of HIV infection should also be emphasized for all persons diagnosed with TB.
Fatigue Life Prediction of Rolling Bearings Based on Modified SWT Mean Stress Correction
Authors: Yu Aodi , Huang Hong-Zhong , Li Yan-Feng , Li He , Zeng Ying 
Published: December 2020

Abstract
Mean stress has a great influence on fatigue life, commonly used stress-based life prediction models can only fit the test results of fatigue life under specific stress ratio or mean stress but cannot describe the effect of stress ratio or mean stress on fatigue life. Smith, Watson and Topper (SWT) proposed a simple mean stress correction criterion. However, the SWT model regards the sensitivity coefficient of all materials to mean stress as 0.5, which will lead to inaccurate predictions for materials with a sensitivity coefficient not equal to 0.5. In this paper, considering the sensitivity of different materials to mean stresses, compensation factor is introduced to modify the SWT model, and several sets of experimental data are used for model verification. Then, the proposed model is applied to fatigue life predictions of rolling bearings, and the results of proposed method are compared with test results to verify its accuracy.
Differences in Carotid Intima-Media Thickness (CIMT) In Patients With Newly Diagnosed Hypertension, and Chronic Hypertensive Patients Treated by Calcium Channel Blockers (CCB) or Angiotensin Converting Enzyme (ACE)-Inhibitors
Authors: Tantri Ni Luh , Rudijanto Achmad , Samsu Nur , Wursito Wursito 
Published: December 2020

Â Hypertension is a significant risk factor for cardiovascular diseases. It closely related to the inflammatory process and resulting in chronic inflammation, which had a critical role in the progression of atherosclerosis. Carotid Intima-Media Thickness (CIMT) was known as a surrogate marker of atherosclerosis. Anti-hypertensive drugs are expected to affect CIMT. Aim: to examine the difference CIMT between newly diagnosed hypertension and chronic hypertensive treated by ACE-I or CCB. Method: this cross-sectional study was conducted on 12 newly diagnosed hypertensive patients (control or group 1), 9 hypertensive patients treated by CCB (group 2), and 9 hypertensive patients treated by ACE-I (group 3). Their hypertensive condition was controlled at least for 6 months. We compared CIMT of patients and Tumour Necrosis Factor Alfa (TNF-Î±) also Interleukin-6 (IL-6) among the groups. Result: there was a significant difference in CIMT between the group 1 and 2 (0.86 vs 0.70; p = 0.027), group 1 and 3 (0.86 vs 0.69; p = 0.018). There was no significant difference between group 2 and 3 (0.70 vs 0.69; p = 0.88). There was no association between CIMT and TNF-Î±, IL-6, Low-Density Lipoprotein (LDL), triglycerides (TGs) levels, and body mass index (BMI), systolic blood pressure. Conclusion: we found that the CIMT of the control group was thicker than those of the treatment groups. Moreover, differences in the thickness of CIMT of the three groups were not associsted with level of TNF-Î±, IL-6, TG, and LDL, also BMI, and systolic blood pressure.
Effect of Chemotherapy and Hormonal Therapy on Bone Mineral Density in Patients with Breast Cancer in Saiful Anwar Hospital Malang
Authors: Nurshanty Ade , Wardhani Shinta Oktya , Suryana Bagus Putu Putra 
Published: December 2020

Osteoporosis is an important health problem, and the number of patients who suffered from it is increasing. Breast cancer is a condition that has aÂ high risk of osteoporosis. Cancer induced bone disease results from the primary disease, metastatic process, or from therapies against the prime condition, causing bone fragility. Therefore, there are still different opinions regarding the therapeutic effect of breast cancer on bone mineral density. Aim: to determine the effect of chemotherapy and hormonal therapy on bone mineral density in patients with breast cancer in Saiful Anwar Hospital Malang. Method: this is a case-control study conducted in 30 patients with breast cancer who had undergone chemotherapy and hormonal therapy are compared to 30 patients without breast cancer as controls.Â Bone Mineral Density (BMD) was measured by DEXA. Result: there are 53% of breast carcinoma patients having osteopenia and 13% having osteoporosis, with one patient has osteoporosis located in the femoral neck and three patients in lumbar (L1-L4). We obtain a significant T-score (p=0.02) in the great trochanter. Odds Ratio (OR) 0.233 with p = 0.008 showed a protective effect of chemotherapy and hormonal therapy for breast cancer to the bone density. Conclusion: the incidence of osteoporosis in the study was 13%, with the most location in the lumbar spine. Chemotherapy and hormonal therapy had a protective effect on BMD in patients with breast cancer in Saiful Anwar Hospital Malang.