bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Time to Surgery of Colorectal Liver Metastases on Survival
Authors: Chen Emerson Y. , Mayo Skye C. , Sutton Thomas , Kearney Matthew R. , Kardosh Adel , Vaccaro Gina M. , Billingsley Kevin G. , Lopez Charles D. 
Published: February 2020

Abstract
Purpose
Resection of liver-only colorectal liver metastases (CRLM) with perioperative chemotherapy is potentially curative. Specific primary tumor and liver metastasis characteristics have been validated to estimate the risk of recurrence. We hypothesize that the time interval from diagnosis of CRLM to surgery, or time to surgery (TTS), is clinically prognostic.

Methods
Patients from a prospectively maintained institutional database at a Comprehensive Cancer Center from May 2003 to January 2018 were reviewed. Clinicopathologic, perioperative treatment, and TTS data were collected. TTS was categorized into short (< 3 months), intermediate (3–6 months), and long (> 6 months) intervals.

Results
Two hundred eighty-one patients were identified. While overall survival (OS) was similar across TTS, postoperative overall survival (postoperative OS) of long TTS was associated with worse survival, 44 months (95% CI, 34–52) compared to short TTS, 59 months (95% CI, 43–79), and intermediate TTS, 63 months (95% CI, 52–108), both p < 0.01. With regard to long-term OS, intermediate TTS had 5-year OS of 59% and 8-year OS of 43% compared to long TTS (5-year OS 53% and 8-year OS 18%) and short TTS (5-year OS 54% and 8-year OS 29%). Long TTS was negatively associated with postoperative OS on multivariate analysis (HR 1.6, p < 0.01) when adjusting for resection margin, CRLM size, age, and use of postoperative chemotherapy.

Conclusion
Short and intermediate TTS had similar survival although patients with intermediate TTS may have better odds of long-term OS. While long TTS was associated with worse survival, likely due to higher disease burden, long-term survivors were still observed.
Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion
Authors: Edvinsson Lars , Grell Anne-Sofie , Warfvinge Karin 
Published: February 2020

AbstractThe calcitonin gene-related peptide (CGRP) family of neuropeptides, consists of CGRP, adrenomedullin, amylin, and calcitonin. The receptors consist of either calcitonin receptor-like receptor (CLR) or calcitonin receptor (CTR) which for function needs an accessory protein, receptor activity-modifying proteins (RAMPs). CGRP has a pivotal role in primary headaches but the role of the other members of the CGRP family of peptides in headaches is not known. Here, we describe the expression of these molecules in the trigeminal ganglion (TG) to understand more on their possible role(s). Single or double immunohistochemistry were applied on frozen sections of rat TG using primary antibodies against CGRP, procalcitonin, calcitonin, adrenomedullin, amylin, RAMP1/2/3, CLR, and CTR. In addition, mRNA expression was measured by quantitative qPCR on TGs. CGRP and calcitonin showed rich expression in the cytoplasm of small to medium-sized neurons, and co-localized sometimes. Procalcitonin was observed in the glial cells. Immunoreactive fibers storing both CGRP and calcitonin were also observed. Adrenomedullin immunoreactivity was found in the satellite glial cells and in fibers, probably the myelinating Schwann cells. Amylin was found in the cytoplasm in many TG neurons. Levels of mRNA expression for adrenomedullin, amylin, CLR, RAMP1, RAMP2, RAMP3, and CTR were measured using qPCR. The experiments verified the expression of mRNA in the TG with the exception of CTR, which was above the limit of detection indicating little or no mRNA expression. In addition to the well-known CGRP receptor (CLR/RAMP1) and the receptor for calcitonin—CTR, we propose that other receptors exist in the rat TG: adrenomedullin receptor AM2 (CLR/RAMP3) in mainly the satellite glial cells, amylin receptors AMY1 (CTR/RAMP1) in mainly neurons, and AMY3 (CTR/RAMP3) in the satellite glial cells. It is important to compare peptides and receptors side-by-side in studies to help address questions of actions resulting from cross-reactivity between receptors. Several of the diverse biological actions of the CGRP family of peptides are clinically relevant. Our findings demonstrate the specific ligand and receptor sites in the rat trigeminal ganglion, highlighting recognition mechanisms to facilitate drug development.
Apprentices’ Errors in Intrapreneurship: Findings from a Large-Scale Assessment
Authors: Kreuzer Christine , Weber Susanne 
Published: February 2020

AbstractIntrapreneurship competence, as one of the main twenty-first century skills, has moved into focus, as it enables benefits for both organizations and individuals. To foster associated competencies and enable tailor-made instruction, teachers need knowledge not only about what their students can do but also about which errors are typically made within this domain. To identify such knowledge, we analyzed the results from a large-scale assessment (5436 responses). We then classified the errors found according to more overarching error categories and assigned them to the facets of a previously developed and validated intrapreneurship competence model to obtain a deeper understanding of which facets of intrapreneurship are not mastered and what the problems are. Additionally, we refer to more general error types in the domain of creative problem-solving to integrate our findings into the broader discussion. By formulating this error-related information as domain-specific negative knowledge, which refers to “how something is not” or “how something does not work”, respectively, we can use this information constructively when designing instructional means for future tailor-made approaches and individual guidance.
Development of novel mathematical models for laboratory studies of hydrolyzed polyacrylamide polymer injectivity in high-permeability conduits
Authors: Fakher Sherif 
Published: February 2020

AbstractHydrolyzed polyacrylamide polymer (HPAM) is the most used polymer in enhanced oil recovery operations in the oil industry. This is mainly attributed to its cost and availability. An important aspect during polymer injection in the formation for mobility control is the ability to inject the polymer easily and safely in the reservoir without having to deal with extremely high pressure gradients and without risking formation fracture. This research develops two mathematical models that can help obtain values for polymer injectivity as a function of HPAM concentration, injection flowrate, and the porous media pore size. The mathematical models were developed based on experiments conducted previously using different polymer concentrations, pore sizes, and polymer injection flowrates. After the models were developed, different data were used to validate the model and examine its accuracy in determining polymer injectivity. The models were also used to predict polymer injectivity for different conditions and illustrate the pore sizes at which the polymer was not able to propagate in the formation. Since the models have several limitations, these were mentioned in the manuscript in order to reduce any error obtained while using the models.
Estimating Reproduction and Survival of Unmarked Juveniles Using Aerial Images and Marked Adults
Authors: Williams Perry J. , Schroeder Cody , Jackson Pat 
Published: February 2020

AbstractMethods for estimating juvenile survival of wildlife populations often rely on intensive data collection efforts to capture and uniquely mark individual juveniles and observe them through time. Capturing juveniles in a time frame sufficient to estimate survival can be challenging due to narrow and stochastic windows of opportunity. For many animals, juvenile survival depends on postnatal parental care (e.g., lactating mammals). When a marked adult gives birth to, and provides care for, juvenile animals, investigators can use the adult mark to locate and count unmarked juveniles. Our objective was to leverage the dependency between juveniles and adults and develop a framework for estimating reproductive rates, juvenile survival, and detection probability using repeated observations of marked adult animals with known fates, but imperfect detection probability, and unmarked juveniles with unknown fates. Our methods assume population closure for adults and that no juvenile births or adoptions take place after monitoring has begun. We conducted simulations to evaluate methods and then developed a field study to examine our methods using real data consisting of a population of mule deer in a remote area in central Nevada. Using simulations, we found that our methods were able to recover the true values used to generate the data well. Estimates of juvenile survival rates from our field study were 0.96, (95% CRI 0.83–0.99) for approximately 32-day periods between late June and late August. The methods we describe show promise for many applications and study systems with similar data types, and our methods can be easily extended to unmanned aerial platforms and cameras that are already commercially available for the types of images we used.Supplementary materials accompanying this paper appear online.
DC supply structure and protection concept for (hybrid) electric CS-25 aircraft
Authors: Hinz Arne , Aigner Benedikt , De Doncker Rik W. , Stumpf Eike 
Published: February 2020

AbstractThis article proposes a power hybridization factor-dependent DC supply grid layout and fault protection for hybrid electric aircraft. It is based on a regulatory review and an analysis of the grid components regarding their impact on grid layout and protection. The findings are applicable to medium-voltage DC and high-temperature superconductor-based electrical drive trains.
The Role of First Trimester Ultrasonography in Antenatal Care: A Study from a Single Perinatal Institute in India
Authors: Kunapareddy Mythreyi , Vavilala Suseela 
Published: February 2020

AbstractThe aim of this study was to assess the role of ultrasound in first the trimester of pregnancy for confirmation of pregnancy, number of fetuses, chorionicity, amnionicity if multiples, viability, assessment of gestational age, identification of structural anomalies and assessment of risk for chromosomal abnormalities. This was a prospective observational study. All pregnant women registered within 13+6 weeks were offered a routine scan between 11+0 and 13+6 weeks. All scans were done by obstetricians, fetal medicine specialists or radiologists are accredited by the Fetal Medicine Foundation. All pregnant women undergoing 11+0 and 13+6 weeks scan were included. Women beyond 14 weeks of pregnancy and referrals from the other centres not delivered at our institute were excluded from the study. A total of 5923 scans were done between January 2016 and June 2017. Complete follow up was available for 2927 women (49.4%), 1925 (32.5%) are ongoing pregnancies and 1071 (18.08%) pregnant women were lost to follow up. The median maternal age in our study was 28 years and 349 (5.89%) mothers had advanced (> 35 years) maternal age. Increased nuchal translucency (NT) (> 95th percentile) was found in 272 cases (4.59%). Intra-uterine fetal death, miscarriages, termination of pregnancy and cardiac abnormalities were higher among women with an NT > 95th percentile. Statistical analysis included calculation of p values and odd’s ratio. Skull and brain abnormalities were found in 28 cases, cystic hygroma in 20 cases, abdominal wall and spine abnormalities in 16 cases each, bladder abnormalities in 12 cases and cardiac abnormalities in 9 cases. Among 2927 women, 85 (1.43%) were screen positive. After counselling, only 20 women underwent invasive testing. The 11+0 and 13+6 weeks scan helps in determination of fetal viability, gestational age, number of fetuses and chorionicity and screening fetuses at risk for trisomy by including screening for structural abnormalities and plan pregnancy/terminate accordingly.
An integrated group FWA-ELECTRE III approach based on interval type-2 fuzzy sets for solving the MCDM problems using limit distance mean
Authors: Mohamadghasemi A. , Hadi-Vencheh A. , Lotfi F. Hosseinzadeh , Khalilzadeh M. 
Published: February 2020

AbstractThe material handling equipment (MHE) has a close connection with layout of machinery and plays the important role in productivity of servicing or manufacturing systems. Since each of MHE has distinct characteristics than the others with respect to conflicting criteria and design experts may state the different subjective judgments with respect to qualitative criteria, the material handling equipment selection problem (MHESP) can be taken into account as a group multi-criteria decision-making (GMCDM) problem. In this paper, a version of type-2 fuzzy sets (T2FSs), named Gaussian interval type-2 fuzzy sets (GIT2FSs), is first used as an alternative to the traditional triangular membership functions (MFs) to weight criteria and sub-criteria and also evaluate of alternatives with respect to sub-criteria. The synthetic value method of GIT2FSs is then carried out to convert the assessments stated as GIT2FSs for each alternative with respect to each sub-criterion and also weights of criteria (sub-criteria) into the single fuzzy rating and weight, respectively. Then, the fuzzy weighted average (FWA) approach is adopted to integrate the single fuzzy ratings of each alternative with respect to sub-criteria and the single fuzzy weights of sub-criteria under each criterion with the aggregated weighted ratings. In next stage, ELECTRE III (ELimination Et Choix Traduisant la Realite´—elimination and choice translation reality) is generalized with GIT2FSs to select the optimal MHE through a new ranking approach. Moreover, some arithmetic operations and properties are extended to GIT2FSs. In addition, to demonstrate its potential applications, the proposed methodology is implemented in a real case study and an illustrative example, and then, the ranking results are compared with those of the others in the literature. Finally, the sensitivity analysis is carried out to show robustness and stability of the obtained results.
Pronoun drop and prosocial behavior: experimental evidence from Japan
Authors: He Tai-Sen , Riyanto Yohanes E. , Tanaka Saori C. , Yamada Katsunori 
Published: February 2020

AbstractWe join a growing body of literature suggesting that the languages people speak influence their decision-making. We tested whether dropping the first-person pronoun “I” affects pro-social behavior in a dictator game-like setting. To this end, we conducted an online randomized, incentivized experiment with a socially representative sample of 2000 Japanese respondents. We provide compelling causal evidence that pronoun dropping reduces pro-sociality. Given that our results provide little empirical support for previous research findings linking first-person pronoun use and lower pro-sociality, we prescribe caution in using languages as a proxy for culture in several cross-country empirical studies in economics.
Current status and future perspectives for localizing the solar photovoltaic industry in the Kingdom of Saudi Arabia
Authors: AlOtaibi Zaid S. , Khonkar Hussam I. , AlAmoudi Ahmed O. , Alqahtani Saad H. 
Published: February 2020

AbstractSaudi Arabia has developed Saudi Vision 2030, an ambitious plan to reduce the country’s dependence on oil by supporting promising private energy organizations and by developing opportunities that contributes to the national economy. In the manufacturing sector, the government is encouraging technology transfers in the renewable energy industries. It is expected to result in the localization of significant parts of the renewable energy value chain in Saudi Arabia. Solar energy systems are proven renewable energy source globally and domestically, it has its long and vast share of experience, from operations and maintenance, to solar data monitoring and gathering. Wide areas had been identified, where this technology can be highly installed and integrated. Components can be manufactured from locally available raw materials to achieve the final products. This study analyzed the key elements of the value chain for producing crystalline silicon solar photovoltaic systems. This paper presents recommendations for localizing this industry in the Kingdom of Saudi Arabia to align with the goals of Saudi Vision 2030. Although these recommendations are based on the environmental conditions of Saudi Arabia, such are also highly relevant for further application to other countries in the Middle East and North Africa region, where widespread energy transitions from fossil fuels to renewable resources are already taking place.
Study of defecation disorders in elderly patients
Authors: Corrêa Neto Isaac José Felippe , Mosca Neto Mario , Lanfranchi Vanessa Santos , Pedroso Thales Ranieri , Figueiredo Henrique Carvalho e Silva , Mocerino Jéssica , Pascutti Marcia , Robles Laercio 
Published: February 2020

Abstract
Introduction Defecation disorders, whether anal incontinence or chronic intestinal constipation, are frequent pelvic floor alterations in the general population and are more common in those with risk factors,i.e., in the elderly, women with an obstetric background, and those with comorbidities, history of pelvic radiotherapy, diabetics, the bedridden, or those with history of orifice surgery, among others.
Objective To analyze the incidence of defecation disorders in geriatric patients treated at the Medical Specialties Outpatient Service (MSOS) of Hospital Santa Marcelina.
Methods Prospective, randomized study that interviewed the same patients in two moments: 1) subjective anamnesis through spontaneous history and 2) objective anamnesis with specific questionnaires to assess anal incontinence and chronic constipation.
Results Between March 2016 and June 2017, 149 patients were analyzed, of whom 114 (76.5%) were female, with a similar mean age between genders; 51.67% had symptoms of anal incontinence and/or chronic constipation. Only 35.5% of patients with complaints of fecal leakage or flatus spontaneously reported them, while 87.1% of constipated patients did so. In the present study, no significant correlation was observed between the mode of delivery (p = 0.106), pregnancy (p = 0.099), and the number of deliveries (p = 0.126) with anal incontinence. In turn, there was no higher incidence of chronic intestinal constipation in females (p = 0.099) and most patients with this complaint had Bristol type 1 or 2 stools.
Conclusion The incidence of defecation disorders in the geriatric population is high and, most notably, anal incontinence is not spontaneously reported by most patients.
Mixed Bruce–Roberts numbers
Authors: Bivià-Ausina Carles , Ruas Maria Aparecida Soares 
Published: February 2020

AbstractWe extend the notions of μ*-sequences and Tjurina numbers of functions to the framework of Bruce–Roberts numbers, that is, to pairs formed by the germ at 0 of a complex analytic variety X ⊆ ℂn and a finitely ${\mathcal R}(X)$-determined analytic function germ f : (ℂn, 0) → (ℂ, 0). We analyze some fundamental properties of these numbers.
ON THEσ-NILPOTENT NORM AND THEσ-NILPOTENT LENGTH OF A FINITE GROUP
Authors: HU BIN , HUANG JIANHONG , SKIBA ALEXANDER N. 
Published: February 2020

AbstractLetGbe a finite group andσ= {σi|i∈I} some partition of the set of all primes$\Bbb{P}$. ThenGis said to be:σ-primaryifGis aσi-group for somei;σ-nilpotentifG=G1× … ×Gtfor someσ-primary groupsG1, … ,Gt;σ-solubleif every chief factor ofGisσ-primary. We use$G^{{\mathfrak{N}}_{\sigma}}$to denote theσ-nilpotent residualofG, that is, the intersection of all normal subgroupsNofGwithσ-nilpotent quotientG/N. IfGisσ-soluble, then theσ-nilpotent length(denoted bylσ(G)) ofGis the length of the shortest normal chain ofGwithσ-nilpotent factors. LetNσ(G) be the intersection of the normalizers of theσ-nilpotent residuals of all subgroups ofG, that is,$${N_\sigma }(G) = \bigcap\limits_{H \le G} {{N_G}} ({H^{{_\sigma }}}).$$Then the subgroupNσ(G) is called theσ-nilpotent normofG. We study the relationship of theσ-nilpotent length with theσ-nilpotent norm ofG. In particular, we prove that theσ-nilpotent length of aσ-soluble groupGis at mostr(r> 1) if and only iflσ(G/Nσ(G)) ≤r.
Wild carnivores, domestic dogs and ticks: shared parasitism in the Brazilian Cerrado
Authors: Ramos V. N. , Lemos F. G. , Azevedo F. C. , Arrais R. C. , Lima C. F. M. , Candeias I. Z. , Martins M. M. , Sandrin A. C. L. G. , Siqueira S. M. , Szabó M. P. J. 
Published: February 2020

AbstractThe increase of contact between natural and rural areas is prominent in Brazil, due to agricultural activities and concern with the environmental conservation. In this context, domestic animals, wild fauna and humans are exposed to mutual exchange of parasites, microorganisms and diseases. We studied tick parasitism of wild carnivores and domestic dogs, and the environmental of questing ticks, in extensive cattle ranch areas intermingled with natural vegetation, and in a natural reserve, both in a region of Cerrado biome, Midwestern Brazil. From 2008 to 2015, we inspected 119 wild carnivores from nine species, and collected six tick species (Amblyomma sculptum, Amblyomma ovale, Amblyomma dubitatum, Amblyomma tigrinum, Dermacentor nitens and Rhipicephalus microplus). The most numerous and infested hosts were Cerdocyon thous, Lycalopex vetulus, Chrysocyon brachyurus, Puma concolor and Conepatus amazonicus. From 139 domestic dogs, we collected A. sculptum, Rhipicephalus sanguineus and R. microplus. From vegetation, samplings resulted in A. sculptum, A. dubitatum, A. ovale, Amblyomma rotundatum and R. microplus, with dominance of A. sculptum. Domestics and wild animals presented high overlapping of infestations by A. sculptum, a generalist and anthropophilic tick species. This tick is the most important vector of the Brazilian spotted fever, a lethal human disease. This fact elicits attention and requires efforts to monitor the presence of pathogens vectored by ticks circulating in this type of agroecosystem, including in other regions of the Brazil, because the most of the natural vegetation remaining have been increasingly immersed in pastures and agricultural matrix.