bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations Between Television Time and activPAL-Measured Duration and Pattern of Sedentary Time Among Pregnant Women at Risk of Gestational Diabetes in the UK
Authors: Wagnild Janelle M. , Pollard Tessa M. 
Published: February 2020

Background: Television (TV) time is associated with poor cardiometabolic health outcomes. This finding is commonly attributed to duration of sitting or patterns of sitting associated with high TV time, but there is very little evidence on this link. Methods: Pregnant women (n = 167) at risk of gestational diabetes wore an activPAL accelerometer and self-reported their usual TV time in the second trimester. Generalized linear mixed models were used to compare objectively measured total sedentary time (ST), prolonged ST (bouts ≥30 min), and breaks in ST for all hours and evening hours (6 PM–11 PM) between those with high (≥2 h/d) and low TV time. Results: Over all waking hours, those with high TV time had fewer breaks in ST than those with low TV time, exp(b) 0.92; 95% confidence interval, 0.86 to 0.998; there were no differences in total ST or prolonged ST between the 2 groups. Those with high TV time had significantly higher evening ST (b = 9.9; 95% confidence interval, 0.5 to 19.2); there were no differences in prolonged ST or breaks in ST during evening hours. Conclusions: These findings suggest that high TV time may be associated with higher evening ST and fewer breaks in ST. The link between TV time and sitting patterns requires further investigation.
Morphological stability diagram for slowly and rapidly solidifying binary systems
Authors: Galenko Peter K. , Danilov Denis A. 
Published: February 2020

AbstractA linear morphological stability of the solid-liquid interface is analyzed for a binary alloy in the limit of low and high crystal growth velocities. Using the result of this analysis, a diagram of morphologies is derived for a whole range of solidification rates with indicating critical growth velocities for the transitions planar front ⇔ cellular/dendritic structure. It is specially noted that the speed of solute diffusion in the bulk liquid limits the absolute chemical stability velocity from the high-rate transition cells/dendrites ⇒ planar front.
Morphological and molecular characterisation of Aporcelaimellus nigeriensis sp. n. (Dorylaimida: Aporcelaimidae), a remarkable dorylaim from Nigeria
Authors: Rashidifard Milad , Bello Tesleem T. , Fourie Hendrika , Coyne Danny L. , Peña-Santiago Reyes 
Published: February 2020

Summary
A new species of Aporcelaimellus, collected in a watermelon field in Nigeria, is described, including its morphological and molecular (D2-D3 28S-rDNA, 18r-DNA) characterisation. Aporcelaimellus nigeriensis sp. n. is distinguishable by its 2.76-3.55 mm length, very coarse ventral body pores, lip region offset by deep constriction and 24-27 μm broad odontostyle 30-36 μm long at its dorsal and 28-31 μm at its ventral side, neck 648-779 μm long, pharyngeal expansion occupying 54-60% of total neck length, uterus 300-473 μm or 2.1-3.2 body diam. long and tripartite, V = 49-54, tail short and convex conoid (27-41 μm, c = 72-115, c′ = 0.5-0.7), spicules 108-137 μm long, and 9-10 spaced ventromedian supplements with hiatus. LSU analysis revealed a close relationship of A. nigeriensis sp. n. with other Aporcelaimellus species and questioned, once more, the monophyly of Aporcelaimidae. SSU phylogenetic tree was not able to resolve the relationship between the new species and other closely related species.
Introduction: Taiwan, Public Diplomacy, and the World Health Assembly
Authors: Rawnsley Gary D. 
Published: February 2020

This is an introduction by the guest editor to the topical section on ‘Taiwan, Public Diplomacy, and the World Health Assembly’ of this issue of the International Journal of Taiwan Studies. The selected four papers, after a double-blind peer review process, were initially presented at a workshop entitled ‘Public Diplomacy and Taiwan's Campaign to Join the wha’, organised by the Global Communications Research Centre, Department of International Politics, Aberystwyth University, 28 March 2018.
Destabilising Empires from the Margin: Report of the 25th North American Taiwan Studies Association Annual Conference, Seattle, 16–18 May 2019
Authors: Hsu Szu-Yun , Hsiao Agnes Ling-Yu 
Published: February 2020

The 25th natsa post-conference report documents the initiation, organisation, and proceedings of the event, followed by some general reflections on what we can further investigate in the future. This year, we invited scholars worldwide to come together and rethink and offer critiques on the possibilities and challenges facing Taiwan studies by unpacking the idea of ‘empire’ and ‘marginality’. Given that agenda, we opened up discussions on some key topics around researching Taiwan and East Asia, such as political economy, democratisation, transitional justice, reconciliation, lgbtq, and culture studies. Attempting to reposition Taiwan studies in the broader intellectual terrain, a series of insightful dialogues thus emerged, pointing out alternatives of Taiwan studies in the face of empire(s) and marginality. In all, the natsa has formed one of the most widely known and vivid platforms for intellectual exchanges on Taiwan studies and further conversation shall continue alongside the growth of the scholarly community.
LMA Gastro™ airway is feasible during upper gastrointestinal interventional endoscopic procedures in high risk patients: a single-center observational study
Authors: Schmutz Axel , Loeffler Thomas , Schmidt Arthur , Goebel Ulrich 
Published: February 2020

Abstract
Background
Nonoperating room anesthesia during gastroenterological procedures is a growing field in anesthetic practice. While the numbers of patients with severe comorbidities are rising constantly, gastrointestinal endoscopic interventions are moving closer to minimally invasive endoscopic surgery. The LMA Gastro™ is a new supraglottic airway device, developed specifically for upper gastrointestinal endoscopy and interventions. The aim of this study was to evaluate the feasibility of LMA Gastro™ in patients with ASA physical status ≥3 undergoing advanced endoscopic procedures.

Methods
We analyzed data from 214 patients retrospectively who received anesthesia for gastroenterological interventions. Inclusion criteria were upper gastrointestinal endoscopic interventions, airway management with LMA Gastro™ and ASA status ≥3. The primary outcome measure was successful use of LMA Gastro™ for airway management and endoscopic intervention.

Results
Thirtyone patients with ASA physical status ≥3, undergoing complex and prolonged upper gastrointestinal endoscopic procedures were included. There were 7 endoscopic retrograde cholangiopancreatographies, 7 peroral endoscopic myotomies, 5 percutaneous endoscopic gastrostomies and 12 other complex procedures (e.g. endoscopic submucosal dissection, esophageal stent placement etc.). Of these, 27 patients were managed successfully using the LMA Gastro™. Placement of the LMA Gastro™ was reported as easy. Positive pressure ventilation was performed without difficulty. The feasibility of the LMA Gastro™ for endoscopic intervention was rated excellent by the endoscopists. In four patients, placement or ventilation with LMA Gastro™ was not possible.

Conclusions
We demonstrated the feasibility of the LMA Gastro™ during general anesthesia for advanced endoscopic procedures in high-risk patients.

Trial registration
German Clinical Trials Register (DRKS00017396) Date of registration: 23rd May 2019, retrospectively registered.
Lower-limb muscle strength: normative data from an observational population-based study
Authors: Pasco Julie A. , Stuart Amanda L. , Holloway-Kew Kara L. , Tembo Monica C. , Sui Sophia X. , Anderson Kara B. , Hyde Natalie K. , Williams Lana J. , Kotowicz Mark A. 
Published: February 2020

Abstract
Background
The extent of muscle deterioration associated with ageing or disease can be quantified by comparison with appropriate reference data. The objective of this study is to present normative data for lower-limb muscle strength and quality for 573 males and 923 females aged 20-97 yr participating in the Geelong Osteoporosis Study in southeastern Australia.

Methods
In this cross-sectional study, measures of muscle strength for hip flexors and hip abductors were obtained using a Nicholas manual muscle tester, a hand-held dynamometer (HHD; kg). Leg lean mass was measured by dual energy x-ray absorptiometry (DXA; kg), and muscle quality calculated as strength/mass (N/kg).

Results
For both sexes, muscle strength and quality decreased with advancing age. Age explained 12.9–25.3% of the variance in muscle strength in males, and 20.8–24.6% in females; age explained less of the variance in muscle quality. Means and standard deviations for muscle strength and quality for each muscle group are reported by age-decade for each sex, and cutpoints equivalent to T-scores of − 2.0 and − 1.0 were derived using data from young males (n = 89) and females (n = 148) aged 20–39 years.

Conclusions
These data will be useful for quantifying the extent of dynapenia and poor muscle quality among adults in the general population in the face of frailty, sarcopenia and other age-related muscle dysfunction.
Human fallopian tube epithelial cells exhibit stemness features, self-renewal capacity, and Wnt-related organoid formation
Authors: Chang Yu-Hsun , Chu Tang-Yuan , Ding Dah-Ching 
Published: February 2020

Abstract
Background
Fallopian tube epithelial cells (FTEC) were thought to be the origin of high-grade serous ovarian carcinoma (HGSOC). Knowledge of the stemness or initiating characteristics of FTEC is insufficient. Previously, we have characterized the stemness cell marker of FTEC, this study aims to further characterize the clonogenicity and spheroid features of FTEC.

Methods
We successfully derived FTECs from the epithelial layer of the human fallopian tubes. We examined the morphology, proliferation rate, doubling time, and clonal growth of them. At passage 3, the sphere formations on gelatin-coated culture, suspension culture, and matrigel culture were observed, and the expression of LGR5, SSEA3, SSEA4, and other stemness markers was examined. Furthermore, tissue-reconstituted organoids from coculture of FTEC, fallopian stromal cells (FTMSC) and endothelial cells (HUVEC) were examined.

Results
FTEC exhibited cuboidal cell morphology and maintained at a constant proliferation rate for up to nine passages (P9). FTEC could proliferate from a single cell with a clonogenic efficiency of 4%. Flow cytometry revealed expressions of normal stem cell markers (SSEA3, SSEA4, and LGR5) and cancer stem cell markers (CD24, CD44, CD117, ROR1, and CD133). FTEC formed spheres and colonies when cultured on low attach dish. In the presence of Matrigel, the stemness and colony formation activity were much enhanced. In co-culturing with FTMSC and HUVEC, FTEC could form organoids that could be blocked by Wnt inhibitor DKK1. Expressions of LGR5 and FOXJ1 expression were also decreased by adding DKK1.

Conclusion
We demonstrated abundantly presence of stem cells in human FTECs which are efficient in forming colonies, spheres and organoids, relying on Wnt signaling. We also reported for the first time the generation of organoid from reconstitutied cell lineages in the tissue. This may provide a new model for studying the regneration and malignant transformation of the tubal epithelium.
Mechanisms underlying direct actions of hyperlipidemia on myocardium: an updated review
Authors: Yao Yu Si , Li Tu Di , Zeng Zhi Huan 
Published: February 2020

AbstractHyperlipidemia is a common metabolic disorder and one of risk factors for cardiovascular disease. Clinical studies have shown that hyperlipidemia increases the risk of non-ischemic heart failure, while decreasing serum lipids can reverse heart dysfunction. Apart from indirectly affecting the function of the heart by promoting the development of atherosclerosis, hyperlipidemia also affects the systolic function and cardiac electrophysiological response of the heart directly, which may be related to gradual accumulation of cardiac lipids and consequent systemic oxidative stress, proinflammatory state and mitochondrial dysfunction. However, the mechanism underlying direct effects of hyperlipidemia on the heart are not fully understood. In this review, we provide an updated summary of recent experimental and clinical studies that focus on elucidating the mechanisms of the action of hyperlipidemia on cardiac function, the relationship between heart failure and serum lipids, and protective effects of lipid-lowering drugs on the heart. The exciting progress in this field supports the prospect of guiding early protection of the heart to benefit the patients with chronic hyperlipidemia and familial hyperlipidemia.
Cryopreserved fascia lata allograft use in surgical facial reanimation: a retrospective study of seven cases
Authors: Silan Francesco , Consiglio Fabio , Dell’Antonia Francesco , Montagner Giulia , Trojan Diletta , Berna Giorgio 
Published: February 2020

Abstract
Background
Facial palsy treatment comprises static and dynamic techniques. Among dynamic techniques, local temporalis transposition represents a reliable solution to achieve facial reanimation. The present study describes a modification of the temporalis tendon transfer using a cryopreserved fascia allograft.

Case presentation
Between March 2015 and September 2018, seven patients with facial palsy underwent facial reanimation with temporalis tendon transfer and fascia lata allograft. Patients with long-term palsy were considered, and both physical and social functions were evaluated. The mean follow-up time was 21.5 months. No immediate complications were observed. Patients reported improvement in facial symmetry both in static and dynamic. Improvement was noticed also in articulation, eating, drinking, and saliva control. The Facial Disability Index revealed an improvement both in physical function subscale and in the social/well-being function subscale.

Conclusions
This modified orthodromic technique allows to reduce the operative time and the risk of complications connected to the use of autologous tissues. The use of the cryopreserved fascia allografts from cadaveric donors seems to provide promising and long-standing results in the treatment of facial palsy.
Tinnitus With Unexpected Spanish Roots: Head and Neck Paragangliomas Caused by SDHAF2 Mutation
Authors: Roose Laura Maria , Rupp Niels J , Röösli Christof , Valcheva Nadejda , Weber Achim , Beuschlein Felix , Tschopp Oliver 
Published: February 2020

AbstractIt is estimated that up to 40% of all head and neck paragangliomas (HNPGL) have a hereditary background with the most common mutations being found in the succinate dehydrogenase (SDH) genes. SDHAF2 mutation leads to the rare paraganglioma syndrome 2. The authors present the case of a 15-year-old male patient with 2, non-secretory HNPGLs, presenting with left-sided, pulsatile tinnitus, and hearing loss. Imaging led to the suspicion of a jugulotympanic paraganglioma on the left, as well as a carotid body tumor on the right. After resection of the jugulotympanic tumor, histology confirmed the presence of a paraganglioma; immunohistochemistry furthermore suggested a loss of SDHB expression. Genetic testing revealed a rare germline, loss-of-function mutation in the SDHAF2 gene, previously described to cause hereditary paraganglioma syndrome 2. Twenty months after the first operation, the patient underwent a resection of the right carotid body paraganglioma. Plasma-free metanephrines/catecholamines always remained within the reference range; the patient is under regular follow-up, and his relatives will be screened. Our findings emphasize the relevance of genetic testing in patients with HNPGL, also with negative family history, especially when the patients present at a young age and with multiple lesions.
Characterisation and feasibility study for superradiant lasing in 40Ca atoms
Authors: Gogyan A. , Kazakov G. , Bober M. , Zawada M. 
Published: February 2020

Superradiant active clocks operating on narrow linewidth clock transitions are predicted to achieve precision orders of magnitude higher than any currently existing optical atomic clocks. We introduce a theory of superradiant lasing and implement it for the example of 40Ca atoms. The presented model, however, is valid for any two- or three-level system in an optical lattice. We perform a feasibility analysis and suggest a set of parameters for the experimental fulfillment of superradiant lasing in Ca. Moreover, we present an overview of different magic wavelengths for the 4s2 1S0 ↔ 4s4p 3P1 (m
J
= 0) transition in Ca for different polarizations and a robustness analysis of these magic conditions. We also report the magic-zero wavelengths for the 4s4p 3P1, m
J
= 0 state.
Protective effects of prebiotic (resistant maltodextrin) and silymarin against toxicity of carbon tetrachloride in liver rat and kidney
Authors: G. A. EL. SAYED M. , A. H. FARAG ENAS. , M. Nasr HEBA. 
Published: February 2020

Exposure to carbon tetrachloride induces acute and chronic hepatic injuries as well as renal injuries in rats. Therefore, the current study aimed to evaluate the protective role of prebiotic (digestion resistant maltodextrin) and silymarin against carbon tetrachloride -induced heptorenal toxicity in albino rats. Six groups with ten rats each were used for this purpose; these groups included the control vehicle group that received saline daily for 30 days, prebiotic group (1g/kg, orally) daily for 30 days; silymarin group (200 mg/kg orally) daily for 30 days; carbon tetrachloride group (2.5ml/kg intraperitoneally twice per week for three week; the prebiotic â€“ carbon tetrachloride group; the silymarin â€“ carbon tetrachloride group. The results revealed that carbon tetrachloride significantly increased serum levels of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, total bilirubin cholesterol, triglyceride, urea and creatinine. In addition, there were substantial increase in lipid peroxidation (malondialdehyde) and level of glucose with significant decreases in albumin, total protein, creatinine kinase, hemoglobin and red blood cells. Carbon tetrachloride also caused histological changes in liver and kidney tissues. However, administration of prebiotic and silymarin alone ameliorated the carbon tetrachloride induced liver and kidney damage with improved hematological, lipid profile and glucose level.Â Â
The Electric Supply Chain 4.0
Authors: Zomkowksi Salvi Vinícius 
Published: February 2020

Supply Chain Management is not a Discipline, but it is becoming one. Supply Chain as Network is a modern definition of a field with more than 37 years of reliable scientific publications. And it has great complexity even greater when world is experiencing the Forth Industrial Revolution.

Electricity Supply Chains were delimitated as those compounded by first tier of oil, gas or coal (energy production majority), the generators, the transmitters, the distributor retailer until end-consumer. It has a great complex network constituted by external organisms responsible for coordinating and giving the strategy to the whole system.

Lean and Agile is something less usual in Electricity Supply Chain. This researcher was unable of finding scientific articles reporting directly about that combination. However, Electricity Supply Chain is considered a functional product with long life cycle. The coal, the gas and the oil are also functional products and they are controlled with efficient perspective. It is concluded that Electricity supply chain is more designed for a lean environment to an agile positioning.

The industry 4.0 is transformed the whole Electricity Supply Chain, especially the electric utility. It is using Big Data for generating extra businesses, and for improving operational conditions. The smart meter and the smart grid, using sensors and the Big Data, coordinate a more precise cycle of production and consumption, transforming Electricity Supply Chain into a responsiveness one with real date and virtual networks.
Ancestral Reconstruction of Karyotypes Reveals an Exceptional Rate of Nonrandom Chromosomal Evolution in Sunflower
Authors: Ostevik Kate L , Samuk Kieran , Rieseberg Loren H 
Published: February 2020

AbstractMapping the chromosomal rearrangements between species can inform our understanding of genome evolution, reproductive isolation, and speciation. Here, we present a novel algorithm for identifying regions of synteny in pairs of genetic maps, which is implemented in the accompanying R package syntR. The syntR algorithm performs as well as previous ad hoc methods while being systematic, repeatable, and applicable to mapping chromosomal rearrangements in any group of species. In addition, we present a systematic survey of chromosomal rearrangements in the annual sunflowers, which is a group known for extreme karyotypic diversity. We build high-density genetic maps for two subspecies of the prairie sunflower, Helianthus petiolaris ssp. petiolaris and H. petiolaris ssp. fallax. Using syntR, we identify blocks of synteny between these two subspecies and previously published high-density genetic maps. We reconstruct ancestral karyotypes for annual sunflowers using those synteny blocks and conservatively estimate that there have been 7.9 chromosomal rearrangements per million years, a high rate of chromosomal evolution. Although the rate of inversion is even higher than the rate of translocation in this group, we further find that every extant karyotype is distinguished by between one and three translocations involving only 8 of the 17 chromosomes. This nonrandom exchange suggests that specific chromosomes are prone to translocation and may thus contribute disproportionately to widespread hybrid sterility in sunflowers. These data deepen our understanding of chromosome evolution and confirm that Helianthus has an exceptional rate of chromosomal rearrangement that may facilitate similarly rapid diversification.