bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of heat stress effects on cellular and transcriptional adaptation of bovine granulosa cells
Authors: Khan Adnan , Dou Jinhuan , Wang Yachun , Jiang Xiaolong , Khan Muhammad Zahoor , Luo Hanpeng , Usman Tahir , Zhu Huabin 
Published: February 2020

AbstractBackgroundHeat stress is known to affect follicular dynamics, oocyte maturation, and fertilization by impairing steroidogenic ability and viability of bovine granulosa cell (bGCs). The present study explored the physiological and molecular response of bGCs to different heat stress intensitiesin-vitro. We exposed the primary bGCs to heat stress (HS) at 39 °C, 40 °C and 41 °C along with control samples (38 °C) for 2 h. To evaluate the impact of heat stress on bGCs, severalin vitrocellular parameters including cell apoptosis, intracellular reactive oxygen species (ROS) accumulation andHSP70kinetics were assessed by flow cytometry, florescence microscopy and western blot, respectively. Furthermore, the ELISA was performed to confirm the 17β-estradiol (E2) and progesterone (P4) levels. In addition, the RNA sequencing (RNA-Seq) method was used to get the molecular based response of bGCs to different heat treatments.ResultsOur findings revealed that the HS significantly decreased the cell viability, E2and P4levels in bGCs, whereas, increased the cellular apoptosis and ROS. Moreover, the RNA-Seq experiments showed that all the treatments (39 °C, 40 °C and 41 °C) significantly regulated many differentially expressed genes (DEGs) i.e.BCL2L1, STAR, CYP11A1, CASP3, SOD2, HSPA13, andMAPK8IP1and pathways associated with heat stress, apoptosis, steroidogenesis, and oxidative stress. Conclusively, our data demonstrated that the impact of 40 °C treatment was comparatively detrimental for cell viability, apoptosis and ROS accumulation. Notably, a similar trend of gene expression was reported by RT-qPCR for RNA-seq data.ConclusionsOur study presented a worthy strategy for the first time to characterize the cellular and transcriptomic adaptation of bGCs to heat stress (39, 40 and 41 °C)in-vitro. The results infer that these genes and pathways reported in present study could be useful candidates/indicators for heat stress research in dairy cattle. Moreover, the established model of bGCs to heat stress in the current study provides an appropriate platform to understand the mechanism of how heat-stressed bGCs can affect the quality of oocytes and developing embryo.
Gastroduodenal artery pseudoaneurysm hemorrhage 1 year after laparoscopic distal gastrectomy: a case report
Authors: Kunitomo Aina , Misawa Kazunari , Sato Yozo , Ito Yuichi , Ito Seiji , Hosoi Takahiro , Okuno Masataka , Higaki Eiji , Oshiro Taihei , Natsume Seiji , Kinoshita Takashi , Senda Yoshiki , Abe Tetsuya , Komori Koji , Inaba Yoshitaka , Shimizu Yasuhiro 
Published: February 2020

Abstract
Background
Postoperative bleeding originating from pseudoaneurysms after radical gastrectomy is not common, but it can be fatal. In particular, delayed bleeding that occurs after the seventh postoperative day is rare.

Case presentation
A 54-year-old man underwent laparoscopic distal gastrectomy, D2 lymph node dissection, and Roux en-Y reconstruction for duodenal neuroendocrine tumors. Drainage was performed for a postoperative pancreatic fistula and abdominal abscess. On the 28th postoperative day, he passed a large amount of bloody stool; therefore, emergency esophagogastroduodenoscopy (EGD) and angiography were performed. However, neither examination demonstrated any bleeding foci or pseudoaneurysm. He was conservatively observed and discharged on the 50th postoperative day. Approximately 1 year after the surgery, he passed a bloody stool and experienced hemorrhagic shock. An EGD revealed exposed blood vessels at the duodenal blind end. His condition was diagnosed as a pseudoaneurysm arising from gastroduodenal artery, which ruptured into the duodenum, based on abdominal contrast-enhanced computed tomography findings. Emergency angiography was performed, and the pseudoaneurysm and artery were successfully embolized.

Conclusions
This case illustrates that there is a possibility of delayed bleeding even 1 year after gastrectomy. Such cases may be serious and require immediate and careful management.
Eigenvalue continuity and Gersgorin's theorem
Authors: Li Chi-Kwong , Zhang Fuzhen 
Published: February 2020

Two types of eigenvalue continuity are commonly used in the literature. However, their meanings and the conditions under which continuities are used are not always stated clearly. This can lead to some confusion and needs to be addressed. In this note, the Geršgorin disk theorem is revisited and the issue concerning the proofs of the theorem by continuity is clarified.
Kausalitas Anak dan Orang Tua : Relevansi antara Teori Konvergensi dalam Psikologi Pendidikan Barat dengan Teori Fitrah dalam Perspektif Islam
Authors: Sukarman . 
Published: February 2020

Abstrak: Artikel ini merupakan kajian penelitian konseptual yang akan memaparkan pola hubungan kausalitas anak dan orang tua menurut teori konvergensi dalam psikologi pendidikan barat dan pandangan teori fitrah dalam perspektif pendidikan Islam. Jika kedua teori ini disandingkan maka akan ditemukan relevansi satu sama lain. Hal yang menarik dalam kajian ini adalah kedua teori ini menempatkan seorang anak sebagai pihak penerima pengaruh (pendidikan) sedangkan orang tua diposisikan sebagai pihak pemberi pengaruh (pendidikan) dalam kehidupan anak. Dalam pandangan Islam ketika orang tua telah tiada maka hasil pemberian pengaruh (pendidikan) terhadap anak akan berpengaruh pada kehidupan orang tuanya kelak. Sehingga dalam hal ini akan terdapat hubungan kausalitas antara keduanya. Kajian ini dilatarbelakangi adanya persoalan ketidaksepemahaman tentang tanggung jawab pendidikan antara guru dan orang tua. Metode penelitian menggunakan literature review dalam kajian deskriptif kualitatif. Penelitian ini mencoba membandingkan antara dua teori pendidikan barat dan teori pendidikan Islam. Simpulan dari kajian tentang teori konvergensi dan teori fitrah adalah adanya satu titik temu antara keduanya meskipun kedua teori tersebut bersumber dari sumber yang berbeda yakni literatur barat dan literatur Islam. Kata kunci: kausalitas, konvergensi, Islam.
Penguatan Spritualitas dalam Komunitas Resimen Mahasiswa
Authors: Yudhawati Dian 
Published: February 2020

Abstrak: Spiritualitas merupakan hal yang penting untuk menciptakan manusia yang berkualitas dan manusia yang mampu memahami kebermaknaan hidup. Kemampuan memahami kehidupan dapat membuat seseorang meraih makna dan mengembangkannya menjadi suatu kebahagiaan. Membangun spiritualitas bukanlah sekedar melakukan ritual keagamaan Upaya membangun nilai-nilai spiritual dapat dilakukan pula dalam berbagai kegiatan yang mampu menerima keberagaman sehingga dapat menambah wawasan tentang makna hidup bagi seseorang. Berkembangnya spiritualitas juga dapat ditemukan pada kehidupan komunitas yang memiliki rasa kebersamaan dan kekeluargaan yang kuat. Resimen Mahasiswa merupakan suatu komunitas yang dimaksud dalam penelitian ini. Hasil penelitian menunjukkan tentang adanya penguatan spiritualitas yang dimiliki oleh anggota Resimen Mahasiswa dalam melaksanakan berbagai kegiatan di dalam komunitasnya.Kata kunci : Spiritualitas; Resimen Mahasiswa
Hubungan Tingkat Kepercayaan Diri Dengan Intensitas Penggunaan Media Sosial Whatsapp Pada Mahasiswa Kedokteran 2018
Authors: Annisa Arum Sonia Azahra Nur , Yuliadi Istar , Nugroho Dian 
Published: February 2020

Abstrak. Kepercayaan diri merupakan hasil dari proses pembentukan identitas. Identitas diri yang jelas menghasilkan kepercayaan diri yang tinggi. Identitas yang kabur menurunkan kepercayaan diri. Kepercayaan diri mempengaruhi kemampuan seseorang berkomunikasi dan berinteraksi dengan orang lain yang berarti komunikasi interpersonal. Komunikasi interpersonal di kalangan mahasiswa cukup penting dalam membangun konsep diri, aktualisasi diri, untuk kelangsungan hidup, untuk memperoleh kebahagiaan, untuk menghindarkan diri dari tekanan dan ketegangan. Kepercayaan diri mempengaruhi komunikasi interpersonal berarti kepercayaan diri juga mempengaruhi cara mahasiswa atau remaja pada umumnya dalam berkomunikasi dengan media sosial. Kepercayaan diri yang berbeda – beda pada setiap individu di usia remaja ini yang akan berpengaruh terhadap intensitas penggunaan media sosial mereka. Intensitas penggunaan merupakan tingkat kedalaman dan kekuatan sikap dalam menggunakan atau memanfaatkan fasilitas-fasilitas media sosial dengan memperhatikan durasi waktu dan frekuensi penggunaannya. Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat kepercayaan diri dan intensitas penggunaan media sosial. Hasil menunjukkan bahwa ada hubungan korelasi signifikan negatif antara tingkat kepercayaan diri dengan intensitas penggunaan media sosial WhatsApp pada mahasiswa FK UNS angkatan 2018.Kata Kunci: Intensitas penggunaan WhatsApp, Kepercayaan diri.
Theoretical analysis of compact cylindrical microlenses for terahertz photoconductive antennas in the photomixer regime
Authors: Søndergaard Thomas , Sauer Mikkel O. , Nielsen Carl E. M. , Merring-Mikkelsen Lars , Sørensen Christian B. , Skovsen Esben 
Published: February 2020

A terahertz photoconductive antenna placed on the back side of a semiconductor slab with and without a compact cylindrical semiconductor microlens on the front side is studied theoretically. The antenna is operated as a photomixer giving narrowband radiation at 1 THz. Radiation patterns and emitted powers are found to oscillate with slab thickness as a consequence of multiple-reflection interference. It is further shown that an antireflection layer on the lens may eliminate these oscillations to a large extent. In the absence of a lens, most of the radiation is trapped inside the semiconductor slab, and the radiation pattern is far from that of a pencil-beam. Both light trapping and radiation patterns are shown to be significantly improved by a very compact lens with a size smaller than a cubic wavelength. The improvements on outcoupling of radiation in a predominantly forward direction versus lens radius and height are mapped out. The calculated outcoupling efficiency of the antenna-lens system takes into account the Purcell effect and radiation trapped in the semiconductor slab. The antenna-lens system is modeled rigorously by using the Green’s function volume integral equation method in a form that exploits cylindrical symmetry.
Omni-resonant space–time wave packets
Authors: Shiri Abbas , Yessenov Murat , Aravindakshan Rohinraj , Abouraddy Ayman F. 
Published: February 2020

We describe theoretically and verify experimentally a novel, to the best of our knowledge, class of diffraction-free pulsed optical beams that are “omni-resonant”: they have the remarkable property of transmission through planar Fabry–Perot resonators without spectral filtering, even if their bandwidth far exceeds the cavity linewidth. Ultrashort wave packets endowed with a specific spatiotemporal structure couple to a single resonant mode independent of its linewidth. We confirm that such “space–time” omni-resonant wave packets retain their bandwidth (1.6 nm), spatiotemporal profile (1.3-ps pulse width, 4-µm beam width), and diffraction-free behavior upon transmission through cavities with resonant linewidths of 0.3 nm and 0.15 nm.
Generation of a broadband chaotic laser by active optical feedback loop combined with a high nonlinear fiber
Authors: Yang Qiang , Qiao Lijun , Zhang Mingjiang , Zhang Jianzhong , Wang Tao , Gao Shaohua , Chai Mengmeng , Menjabin Mohiuddin Promi 
Published: February 2020

We propose and demonstrate a method to generate a flat broadband chaotic laser by using an active optical feedback loop combined with a high nonlinear fiber. The feedback strength and nonlinear effect, especially the four-wave mixing effect of high nonlinear fiber, are studied to improve the bandwidth and flatness of chaos. When the feedback strength is 6.6 and injected fiber power is 1.0 W, a chaotic signal with a frequency range over 50 GHz, 80% bandwidth of 38.9 GHz, and flatness of 4.2 dB are experimentally achieved.
Multiprojective witness sets and a trace test
Authors: Hauenstein Jonathan D. , Rodriguez Jose Israel 
Published: February 2020

Abstract
In the field of numerical algebraic geometry, positive-dimensional solution sets of systems of polynomial equations are described by witness sets. In this paper, we define multiprojective witness sets which encode the multidegree information of an irreducible multiprojective variety. Our main results generalise the regeneration solving procedure, a trace test, and numerical irreducible decomposition to the multiprojective case. Examples are included to demonstrate this new approach.
Generators of Maximal Subgroups of Harada-Norton and some Linear Groups
Authors: Liu Jia-Bao , Yasin Faisal , Farooq Adeel , Haq Absar Ul 
Published: February 2020

AbstractGroup theory, the ultimate theory for symmetry, is a powerful tool that has a direct impact on research in robotics, computer vision, computer graphics and medical image analysis. Symmetry is very important in chemistry research and group theory is the tool that is used to determine symmetry. Usually, it is not only the symmetry of molecule but also the symmetries of some local atoms, molecular orbitals, rotations and vibrations of bonds, etc. that are important. Harada-Norton group is an example of a sporadic simple group. There are 14 maximal subgroups of Harada-Norton group. Generators (also known as words) of 11 maximal subgroups are already known. The aim of this note is to give generators of the remaining 3 maximal subgroups, which is an open problem mentioned on A World-wide-web Atlas of Group Representations (http://brauer.maths.qmul.ac.uk/Atlas) [1]. In this report we compute the generators of A6 × A6.D8, 23+2+6.(3 × L3(2)) and 34 : 2.(A4 × A4).4. Moreover we also compute the generators for the Maximal subgroups of some linear groups.
Instance-Optimal Goal-Oriented Adaptivity
Authors: Innerberger Michael , Praetorius Dirk 
Published: February 2020

Abstract
We consider an adaptive finite element method with arbitrary but fixed polynomial degree

p
≥
1

{p\geq 1}

, where adaptivity is driven by an edge-based residual error estimator.
Based on the modified maximum criterion from
[L. Diening, C. Kreuzer and R. Stevenson,
Instance optimality of the adaptive maximum strategy,
Found. Comput. Math. 16 2016, 1, 33–68],
we propose a goal-oriented adaptive algorithm and prove that it is instance optimal.
More precisely, the goal error is bounded by the product of the total errors (being the sum of energy error plus data oscillations) of the primal and the dual problem, and the proposed algorithm is instance optimal with respect to this upper bound.
Numerical experiments underline our theoretical findings.
Atom-specific persistent homology and its application to protein flexibility analysis
Authors: Bramer David , Wei Guo-Wei 
Published: February 2020

Abstract
Recently, persistent homology has had tremendous success in biomolecular data analysis. It works by examining the topological relationship or connectivity of a group of atoms in a molecule at a variety of scales, then rendering a family of topological representations of the molecule. However, persistent homology is rarely employed for the analysis of atomic properties, such as biomolecular flexibility analysis or B-factor prediction. This work introduces atom-specific persistent homology to provide a local atomic level representation of a molecule via a global topological tool. This is achieved through the construction of a pair of conjugated sets of atoms and corresponding conjugated simplicial complexes, as well as conjugated topological spaces. The difference between the topological invariants of the pair of conjugated sets is measured by Bottleneck and Wasserstein metrics and leads to an atom-specific topological representation of individual atomic properties in a molecule. Atom-specific topological features are integrated with various machine learning algorithms, including gradient boosting trees and convolutional neural network for protein thermal fluctuation analysis and B-factor prediction. Extensive numerical results indicate the proposed method provides a powerful topological tool for analyzing and predicting localized information in complex macromolecules.
Anger stinks in Seri: Olfactory metaphor in a lesser-described language
Authors: O’Meara Carolyn , Majid Asifa 
Published: February 2020

AbstractPrevious studies claim there are few olfactory metaphors cross-linguistically, especially compared to metaphors originating in the visual and auditory domains. We show olfaction can be a source for metaphor and metonymy in a lesser-described language that has rich lexical resources for talking about odors. In Seri, an isolate language of Mexico spoken by indigenous hunter-gatherers, we find a novel metaphor for emotion never previously described – “anger stinks”. In addition, distinct odor verbs are used metaphorically to distinguish volitional vs. non-volitional states-of-affairs. Finally, there is ample olfactory metonymy in Seri, especially prevalent in names for plants, but also found in names for insects and artifacts. This calls for a re-examination of better-known languages for the overlooked role olfaction may play in metaphor and metonymy. The Seri language illustrates how valuable data from understudied languages can be in highlighting novel ways by which people conceptualize themselves and their world.
Burnside rings of fusion systems and their unit groups
Authors: Barsotti Jamison , Carman Rob 
Published: February 2020

Abstract
For a saturated fusion system

ℱ

{\mathcal{F}}

on a p-group S, we study the Burnside ring of the fusion system

B
⁢

(
ℱ
)

{B(\mathcal{F})}

, as defined by Matthew Gelvin and Sune Reeh, which is a subring of the Burnside ring

B
⁢

(
S
)

{B(S)}

.
We give criteria for an element of

B
⁢

(
S
)

{B(S)}

to be in

B
⁢

(
ℱ
)

{B(\mathcal{F})}

determined by the

ℱ

{\mathcal{F}}

-automorphism groups of essential subgroups of S.
When

ℱ

{\mathcal{F}}

is the fusion system induced by a finite group G with S as a Sylow p-group, we show that the restriction of

B
⁢

(
G
)

{B(G)}

to

B
⁢

(
S
)

{B(S)}

has image equal to

B
⁢

(
ℱ
)

{B(\mathcal{F})}

.
We also show that, for

p
=
2

{p=2}

, we can gain information about the fusion system by studying the unit group

B
⁢

(
ℱ
)

×

{B(\mathcal{F})^{\times}}

.
When S is abelian, we completely determine this unit group.
Empirical Evaluation of High-speed Cost-effective Ro-FSO System by Incorporating OCDMA-PDM Scheme under the Presence of Fog
Authors: Chaudhary Sushank , Choudhary Sunita , Tang Xuan , Wei Xian 
Published: February 2020

Abstract
Radio over free space optics (Ro-FSO) innovation saddles the vast limit of optical fiber and the portability from local to remote systems. To enhance the capacity of Ro-FSO systems without compromising the bandwidth, this work incorporates use of hybrid polarization division multiplexing (PDM) with optical code division multiplexing (OCDMA) schemes. Due to low deployment time and support cost, the vast majority of the current optical network application systems adopts free space optics (FSO) as the elective answer for suitably supplanting fiber optical cable. This study has incorporated PDM and OCDMA schemes to design a 50 Gbps Ro-FSO link. Ten channels, each with 5 Gbps of data, are transported via FSO link of 3500 m. In addition, the proposed PDM-OCDMA-Ro-FSO link is evaluated under various atmospheric commotions.
Assessment of intima-media thickness of the carotid artery and intraluminal diameter of the brachial artery as cardiovascular risk markers in Brazilian adolescents with overweight or obesity
Authors: Ribeiro Alessandra C.R. , Lyra Arthur , Bonfitto Alexandre J. , Tostes Filho Gilmar V. , Zanesco Leonardo , Fleury Eduardo F.C. , Ferreira Aleksandro B. , Longui Carlos A. , Monte Osmar , Kochi Cristiane 
Published: February 2020

Abstract

Background
The intima-media thickness of the carotid artery (cIMT) and endothelial dysfunction are associated with cardiovascular (CV) disease.

Objectives
To evaluate the correlation between cIMT, brachial intraluminal diameter and flow-mediated vasodilation on the reactive hyperemia phase in adolescents with obesity with predictors of CV risk.

Methods
Seventy-three pubertal patients with overweight or obesity were evaluated (45 girls) with a mean (standard deviation [SD]) age of 12.9 (2.5) years. Patients underwent anthropometric measurements and had the lipid profile, oral glucose tolerance test (oGTT) and serum intercellular adhesion molecule-1 (sICAM-1) levels analyzed. The ratios of the waist circumference (WC)/height (WHtR) and triglycerides (TG)/high-density lipoprotein cholesterol (HDL-C), homeostatic model assessment of insulin resistance (HOMA-IR), the Matsuda index and insulin area under the curve (AUC) were calculated. All patients were evaluated for cIMT and arterial blood flow velocity of the brachial artery.

Results
75.3% of the patients had high cIMT values. We found a positive correlation between WHtR and cIMT (r = 0.233; p = 0.050). There was a positive correlation between sICAM-1 and insulin AUC (r = 0.323; p = 0.012) and WHtR (r = 0.258; p = 0.047). Patients with abnormal arterial dilation had higher sICAM-1 values (p = 0.02) despite having smaller WHtR (p = 0.046).

Conclusions
These adolescents with obesity had high cIMT values. Insulin resistance was associated with sICAM-1. Endothelial dysfunction was positively correlated with sICAM-1. There is no consensus about what the best laboratorial approach to evaluate insulin resistance in adolescents is, and the cutoff values of each method are arbitrary. So, as we saw earlier, the association between anthropometric data (WHtR) and ultrasound findings could be useful to evaluate the CV risk of these adolescents with obesity, because of its practical, direct and low-cost value.
The association between vitamin D levels and precocious puberty: a meta-analysis
Authors: Liu Shanshan , Zhu Xun , Wang Yuanxin , Yan Shoumeng , Li Dong , Cui Weiwei 
Published: February 2020

Abstract
The objective of this short communication was the relationship between vitamin D and precocious puberty (PP). In this study, a comprehensive search of multiple databases was performed to identify studies focused on the association between vitamin D deficiency and PP. Studies that compared serum vitamin D levels between patients with PP and controls were selected for the systematic meta-analysis. The main outcome was the mean difference in serum vitamin D levels between PP and controls. Vitamin D-deficient subjects were more likely to develop PP. Our findings suggest that PP may be linked to vitamin D deficiency. Thus, providing supplements of vitamin D to PP patients may improve their nutritional status and prevent diseases. But, the amount of vitamin D required is uncertain, so it is important to be careful when taking vitamin D supplements.