bluuebunny/crossref_metadata_2025_split huggingface dataset:
In-phase/quadrature modulation using directly reflectivity-modulated laser
Authors: Dong Po , Melikyan Argishti , Kim Kwangwoong , Kaneda Noriaki , Stern Brian , Baeyens Yves 
Published: July 2020

In the last decade, coherent optical transmission technology has dominated the provision of high-capacity communications in metro and long-haul networks and is expected to expand to short-reach networks such as data center and passive optical networks. Capacities of more than 1.5 Tb/s have been demonstrated for a single wavelength. In-phase/quadrature (IQ) modulation allows information to be encoded in both the phase and amplitude of light (or in-phase and quadrature components) and is typically achieved by nested multiple Mach–Zehnder modulators (MZMs). MZMs have advantages including low chirp, broadband operation, and easy to achieve high-order quadrature amplitude modulation (QAM), but they are typically large and have high RF power consumption and excess losses. A small IQ transmitter with low RF power consumption is therefore in demand for low-cost and highly integrated coherent modules. In this paper, we experimentally demonstrate a directly reflectivity-modulated laser that can potentially achieve this goal. We demonstrate the device on a hybrid silicon/III-V platform, where silicon photonics offers compact components for filters, modulators, and reflectors, and the III-V material provides gain. In principle, the device could inherit the benefits of conventional directly modulated lasers while overcoming their speed limits. We demonstrate 32/50 Gbaud quadrature phase-shifted keying with low bit error ratios and experimentally prove the feasibility of 30 Gbaud 16-QAM.
ESTUDO DE EQUIVALÊNCIA FARMACÊUTICA DE COMPRIMIDOS DE CLORIDRATO DE METFORMINA GENÉRICOS E SIMILARES
Authors: Silva Thalita Prates da , Teodoro Emilly Isabelli dos Santos , Paula Mariana Nascimento de , Mello João Carlos Palazzo de , Medeiros Araújo Daniela Cristina de 
Published: July 2020

A metformina é um hipoglicemiante oral da classe das biguanidas muito utilizado no tratamento de diabetes mellitus tipo 2. Os estudos de equivalência farmacêutica destinam-se à avaliação de alguns parâmetros de qualidade dos medicamentos por meio de análise comparativa entre o(s) medicamento(s) teste e o medicamento de referência. Dessa maneira, o presente trabalho teve como objetivo avaliar a equivalência farmacêutica de comprimidos de duas marcas de medicamento genérico e duas marcas de similar frente ao medicamento referência de cloridrato de metformina 850 mg. Os testes realizados nas amostras foram peso médio, teor de substância ativa, friabilidade, desintegração e dissolução. As amostras testadas foram aprovadas em todos os testes, encontrando-se dentro dos limites preconizados pela farmacopeia brasileira 5ª edição. Assim pode-se afi rmar que todos os medicamentos testados são equivalentes farmacêuticos do medicamento referência.
Retention Practices Among Orthodontists in Morocco
Authors: Ben Mohimd Hajar , Lmaroudia Oulad , Zaoui Fatima , Bahije Loubna 
Published: July 2020

Introduction: Retention is the orthodontic treatment phase which ensures that the teeth are maintained in their corrected positions. There are currently various protocols of retention commonly adopted by orthodontists. The objective of this study is to evaluate the retention procedures which are used by orthodontists in the private practice.Materials and methods: This was a cross-sectional descriptive analytical study which targeted orthodontists in the city of Rabat- Morocco. 67 questionnaires were distribute to the orthodontists of private practice. The questionnaire was organized into seven sections representing specific information about the socio-demographic status of the respondents, selection of a retention system, details of commonly used fixed and removable retainers, the duration of the retention period, and follow up appointments, instructions for patients, finally the clinical problems encountered during the retainer period. Results: All orthodontists participating in the survey confirmed the indispensable use of an orthodontic retainer after active treatment. The fixed retainer was the preferred choice of the majority of our orthodontists in the mandibular arch for the different clinical situations whereas, at the maxillary arch, more than 30% of orthodontists use both types of retainer (fixed and removable). 62.5% of orthodontists choose a vacuum-formed retainer as a removable retainer. For fixed retainer, the bonded canine to canine was most preferred by the majority of orthodontists in the upper and lower arches. 50% of orthodontists recommend lifetime orthodontic retainer with follow-up appointments of 2 to 3 times/year. Conclusions: This survey provides an overview of orthodontic retention procedures adopted by orthodontists in the region. A multitude of responses let us conclude that guidelines are desired to find a common protocol.
Toxoplasma gondii infection and multiple sclerosis: An age- and a gender-matched case-control seroprevalence study
Authors: Méndez-Hernández Edna Madai , Hernández-Tinoco Jesús , Salas-Pacheco José Manuel , Sánchez-Anguiano Luis Francisco , Arias-Carrión Oscar , Sandoval-Carrillo Ada Agustina , Castellanos-Juárez Francisco Xavier , Ruano-Calderón Luis Ángel , Alvarado-Esquivel Cosme 
Published: July 2020

AbstractThe link between Toxoplasma gondii infection and multiple sclerosis remains controversial. In the present study, we aimed to determine the association between T. gondii seropositivity and multiple sclerosis. Using an age- and gender-matched case-control study, we studied 45 patients who had multiple sclerosis attended in two public hospitals and 225 control subjects without this disease and other neurological disorders in Durango City, Mexico. Serum samples of cases and controls were analyzed for detection of anti-Toxoplasma IgG using a commercially available enzyme-linked immunoassay. One (2.22%) of the 45 patients with multiple sclerosis, and 15 (6.67%) of the 225 control subjects without this disease were seropositive for anti-T. gondii IgG antibodies. No statistically significant difference (OR = 0.31; 95% CI: 0.04–2.47; P = 0.48) in seroprevalence of anti-T. gondii IgG antibodies between cases and controls was found. The frequency of T. gondii seropositivity did not vary among cases and controls about sex or age groups. Results of this study do not support an association between seropositivity to T. gondii and multiple sclerosis. However, additional research with larger sample sizes to confirm this lack of association should be conducted.
Serpentinization as a route to liberating phosphorus on habitable worlds
Authors: Pasek Matthew , Omran Arthur , Lang Carolyn , Gull Maheen , Abbatiello Josh , Feng Tian , Garong Lyle , Abbott-Lyon Heather 
Published: July 2020

Abstract
Planetary habitability is in part governed by nutrient availability, including the availability of the element phosphorus. The nutrient phosphorus plays roles in various necessary biochemical functions, and its biogeochemical cycling has been proposed to be extremely slow due to a strong coupling to the rock cycle via mineral weathering. Here we show a route to P liberation from water-rock reactions that are thought to be common throughout the Solar System. We report the speciation of phosphorus in serpentinite rocks to include the ion phosphite (HPO32- with P3+) and show that reduction of phosphate to phosphite is predicted from thermodynamic models of serpentinization. As a result, as olivine in ultramafic rocks alters to serpentine minerals, phosphorus as soluble phosphite should be released under low redox conditions, liberating this key nutrient for life. Thus, this element may be accessible to developing life where water is in direct contact with ultramafic rock, providing a source of this nutrient to potentially habitable worlds.
Periplogenin Activates ROS-ER Stress Pathway to Trigger Apoptosis via BIP-eIF2α- CHOP and IRE1α-ASK1-JNK Signaling Routes
Authors: Yang Yingjuan , Liu Yana , Zhang Yanhua , Ji Wei , Wang Lan , Lee Shao C. 
Published: July 2020

Background:
Periplogenin (PPG), a natural compound isolated from traditional Chinese herb Cortex
Periplocae, has been reported to possess anti-inflammatory and anti-cancer properties.

Objective:
The present study aims to investigate the antitumor effects of PPG and the underlying mechanism in
human colorectal cancer cells.

Methods:
The inhibition of cell growth in vitro was assessed by MTT assay. The induction of apoptosis and the
ROS production induced by PPG was investigated by flow cytometry analysis. Western blotting was applied to
measure the protein expression. Small interference RNA (siRNA) and a specific pharmacological inhibitor were
used to knock down or inhibit the expression of related genes.

Results:
PPG was able to cause the production of ROS, inhibit the cancer cell growth and induce apoptosis. Nacetylcysteine
was able to inhibit ROS production and apoptosis. PPG up-regulated the protein levels of BIP, peIF2α
and CHOP as well as IRE1α and p-JNK, and down-regulated the protein level of p-ASK1, all of which
were reversed by N-acetylcysteine. Importantly, knockdown of CHOP or JNK protein level attenuated the PPGelicited
apoptosis.

Conclusion:
PPG-induced apoptosis was regulated by ROS-mediated BIP/eIF2α/CHOP and BIP/ASK1/JNK
signaling pathways in colon cancer cells, suggesting that PPG is a promising therapeutic agent for the treatment
of human colon cancer.
Las otras víctimas: consecuencias y reconocimiento legal de los menores de edad víctimas de la violencia de género ejercida en el hogar
Authors: Caravaca Llamas Carmen , Sáez Dato Mª Ángeles 
Published: July 2020

La violencia de género es una problemática social que ha motivado numerosas investigaciones relacionadas con la mujer como víctima, pero hasta hace escasos años los menores no eran reconocidos como víctimas de este delito. Esta investigación cualitativa basada en la búsqueda, recopilación y análisis documental y legislativo, tiene el objetivo principal de conceptualizar el reconocimiento normativo como víctimas directas a los hijos e hijas de las mujeres afectadas por la violencia de género y, por tanto, sujetos de atención y protección especializada. Para ello, se recopilan los diferentes efectos producidos en los menores como consecuencia de este tipo de delito y se reflexiona sobre la evolución legislativa producida durante las últimas décadas en España.
Sosioedukasi Tembang Waranggono pada Tayub di Kabupaten Tuban
Authors: Wibowo Arif , Widayati Wahyu 
Published: July 2020

Tayub adalah salah satu bentuk seni pertunjukan tradisional yang tumbuh dan berkembang dengan subur. Tayub menghadirkan waranggono yang menari dan menyanyi nyinden. Tayub yaitu tarian yang dilakukan oleh waranggono dan pengibing dengan iringan gamelan dan tembang. Biasanya untuk meramaikan pesta perkawinan dan sebagainya. Tayub merupakan bentuk pertunjukkan tari rakyat di Jawa yang disajikan oleh penari perempuan (waranggono atau joged) diiringi dengan seperangkat gamelan berlaras selendro atau pelog disertai tembang.Dalam penelitian ini, peneliti tertarik meneliti dua hal yaitu (1) tentang penerimaan masyarakat terhadap tembang waranggono pada tayub di Kabupaten Tuban bagaimana penilaian masyarakat terhadap tembang berdasarkan teori sosiologi sastra. (2) nilai-nilai pendidikan apa saja yang terkandung dalam tembang waranggono pada tayub di Kabupaten Tuban. Penelitian ini merupakan penelitian jenis kualitatif dengan menggunakan metode deskriptif, yang menghasilkan data deskriptif berupa kata-kata yang tertulis atau lisan orang lain dan perilaku yang dapat diamati. Penelitian ini memaparkan tentang penerimaan masyarakat Kabupaten Tuban dan nilai edukasi suatu tembang waranggono dalam pementasan di Kabupaten Tuban yang dianalisis dengan menggunakan teori sosiologi sastra dan nilai edukasi pendidikan. Hasil dari penelitian ini adalah berupa penerimaan masyarakat Kabupaten Tuban terhadap tembang waranggono dalam acara tayub, dan nila-nilai edukasi berupa nilai moral, religi, budaya dan sosial dalam tembang waranggoo yang dibawakan.
Konflik Psikis Dalam Novel Gado-Gado Poligami Karya Leyla Hana Dan Linda Nurhayati (Kajian Psikopragmatis)
Authors: Widayati Wahyu , Andharu Devito 
Published: July 2020

Tujuan penelitian ini adalah (1) mengetahui dan menemukan konflik psikis yang terepresentasi di dalam novel Gado-Gado Poligami karya Leyla Hana dan Linda Nurhayati, (2) mengetahui dan menemukan latar belakang konflik psikis yang tersepresntasi di dalam novel Gado-Gado Poligami karya Leyla Hana dan Linda Nurhayati. Pendekatan penelitian yang digunakan yaitu pendekatan psikopragmatis. Jenis penelitian ini adalah penelitian deskriptif kualitatif. Sumber data di dalam penelitian ini adalah novel Gado-Gado Poligami karya Leyla Hana dan Linda Nurhayati. Teknik pengumpulan data menggunakan teknik close reading, yakni baca, simak, dan kutip (catat). Validitas data menggunakan teknik triangulasi. analisis data yang digunakan adalah teknik pembacaan model semiotik. Hasil analisis penelitan ,yaitu konflik psikis di dalam novel Gado-Gado Poligami karya Leyla Hana dan Linda Nurhayati, meliputi (1) kekecewaan, (2) cemburu,(3) iri, (4) sakit hati, dan (5) pertentangan batin. Sedangkan latar belakang terjadinya konflik psikis di dalam novel Gado-Gado Poligami karya Leyla Hana dan Linda Nurhayati yaitu adanya faktor kekerasan verbal dan faktor ketidakadilan.
Hidden symmetry of the 16D oscillator and its 9D coulomb analogue
Authors: Lavrenov А. N. , Lavrenov I. А. 
Published: July 2020

We present the quadratic Hahn algebra QH(3) as an algebra of the hidden symmetry for a certain class of exactly solvable potentials, generalizing the 16D oscillator and its 9D coulomb analogue to the generalized version of the Hurwitz transformation based on SU (1,1)⊕ SU (1,1) . The solvability of the Schrodinger equation of these problems by the variables separation method are discussed in spherical and parabolic (cylindrical) coordinates. The overlap coefficients between wave functions in these coordinates are shown to coincide with the Clebsch – Gordan coefficients for the SU(1,1) algebra.
Cell phone use policies in the college classroom: Do they work?
Authors: Jones Shannise B. , Aruguete Mara S. , Gretlein Rachel 
Published: July 2020

Abstract
Our study examined the efficacy of lenient and restrictive cell phone policies. We expected that a lenient policy would be associated with lower quiz scores, greater anxiety, and lower GPA. Additionally, we expected students to self-report using their phones mostly for non-academic purposes. We gave one introductory psychology section a restrictive cell phone use policy while another section was given a lenient policy. We observed how often students used their phones during class in both conditions. At the end of the class period, students took a short quiz over the lecture material. Afterward, they were given a survey that measured demographics, attitudes about cell phone use in class, academic motivation, cell phone use domains, and anxiety. In the restrictive policy condition, students used their cell phones in class at a similar rate as in the lenient policy condition, suggesting that the restrictive cell phone policy was ineffective. Students operated their phones an average of about seven times during the 50-minute class period, mostly for non-academic purposes. Our results contribute to a body of literature showing that electronic devices distract students and decrease the efficacy of the learning environment.
Promosi Kesehatan Dengan Metode Focus Group Discussion Dapat Mempengaruhi Pengetahuan Tentang Diabetes Melitus
Authors: Kusaeri Satrio Kusnanda Murdiqi , Haiya Nutrisia Nu’im , Ardian Iwan 
Published: July 2020

Diabetes Melitus merupakan hilangnya toleransi karbohidrat dan hiperglikemia yang menimbulkan penurunan berat badan, guladarah yang tinggi bisa mengakibatkan rusaknya organ-organ tubuh,seperti kebutaan mata, glomerulosklerosis neuropati, ginjal, dan stroke, gagal jantung pada kardiovaskular, serta penyakit kaki diabetic, penggunaan promosi kesehatan metode FGD untuk meningkatkan pengetahuan pada penelitian ini bertujuan untuk melihat pengaruh pengetahuan pada diabetes melitus di Puskesmas Bangetayu Semarang. Jenis penelitian eksperimen semu (quast experimental) with control group design dengan pre - test – post – test. teknik consecutive sampling, consecutive sampling (berurutan), total sempel ada 55 responden, sebanyak 28 untuk kelompok perlakuan dan sebanyak 27 untuk kelompok kontrol. Berdasarkan hasil analisis terdapat pengaruh promosi kesehatan dengan metode Focus Group Discussion terhadap pengetahuan masyarakat tentang diabetes melitus. Terdapat pengaruh promosi kesehatan dengan metode Focus Group Discussion terhadap pengetahuan masyarakat tentang diabetes mellitus.
ANALISIS PENGENDALIAN KUALITAS (QUALITYCONTROL) UNTUK MENINGKATKAN KUALITAS PRODUK YANG DIHASILKAN PADA CV BINA TEHNIK PEMATANGSIANTAR
Authors: Kiki Erina , Lie Darwin , Efendi Efendi , Sisca Sisca 
Published: July 2020

The purpose of this study are: 1. To find out the description of quality control and the products quality produced at CV Bina Tehnik Pematangsiantar. 2. To find out the implementation of quality control to improve the products quality produced at CV Bina Tehnik Pematangsiantar.The results of the study can be summarized as follows: 1. The process of quality control in the production process applied by CV Bina Tehnik Pematangsiantar is not optimal. 2. The aesthetic and conformance dimensions of the product quality produced by CV Bina Tehnik Pematangsiantar are not optimal. 3. From the results of the histogram, irregularities or discrepancies found at the end of the QC or inspection of the final product / finished product are dominated almost 80% by 2 (two) types of non-conformity, namely the state of paint / color and the function of lights and hoses. 4. From the analysis of fishbone diagrams, it is known that the causes of irregularities are derived from raw material, human or worker factors, work methods and the environment. Keyword: Brand Image, Service Quality and Customer Satisfaction
PENGEMBANGAN SDM UNGGUL BERBASIS COLLABORATIVE STRATEGIC MANAGEMENT
Authors: Sugiat Maria Apsari 
Published: July 2020

Perubahan paradigma dari Human Resources menjadi Human Capital Development di era digital saat ini, mengharuskan terjadinya sinergi diantara pemangku kepentingan dalam membangun negara. Sehubungan dengan cita-cita membangun keberlanjutan masyarakat yang unggul, terdapat dua pendekatan yang berbeda dalam pelibatan pemangku kepentingan untuk mengimplementasikan rencana yang sukses, yaitu partisipasi dan kemitraan. Dua hal ini bentuk kolaborasi yang berbeda, perlu disesuaikan dengan kondisi daerah seperti potensi SDM, potensi infrastruktur, dan potensi lainnya. Jenis pendekatan kemitraan dan kolaborasi menjadi pendekatan yang sangat ideal untuk rencana keberlanjutan masyarakat. Terutama tingkat keterlibatan yang tinggi dari pemangku kepentingan organisasi, seperti pemerintah daerah bekerjasama dengan para pemangku kepentingan dalam insiatif membangun SDM berkelanjutan. Sehingga perlu muncul collaborative strategic management dalam melibatkan pengambilan keputusan dan strategi bersama untuk memasukan ide-ide dari berbagai pemangku kepentingan ke dalam pengembangan rencana keberlanjutan masyarakat. Rencana ini melibatkan mitra utama dalam mengimplementasikan dan berkomitmen terhadap tujuan koletif dan tindakan yang akan dilaksanakan Bersama. Tujuan dalam penelitian ini bagaimana membangun SDM unggul baik dari private sector maupun public sector melalui pendekatan collaborative strategic management dan pendekatan human capital development, dengan menghasilkan beberapa temuan dan rekomendasi. Penelitian ini menggunakan metode deskriptif eksploratif, memanfaatkan data literatur dan data-data yang ada dilapangan baik online maupun offline. Hasil penelitian ini adalah rekomendasi pola kemitraan dalam meningkatkan kemampuan sumber daya manusia unggul termasuk melibatkan pemangku kepentingan melalui collaborative strategic management, agar mencapai tujuan yang kolektif dan maju bersama.
PENGARUH SIKAP KONSUMEN DAN PERSEPSI KONSUMEN TERHADAP KEPUTUSAN PEMBELIAN PADA MINI MARKET MAWAR BALIMBINGAN
Authors: Fadhila Siti , Lie Darwin , Wijaya Andy , Halim Fitria 
Published: July 2020

Mini Market Mawar Balimbingan berdiri pada tahun 2002 dengan alamat Jl. Besar Tanah Jawa, Balimbingan Kecamatan Tanah Jawa. Mini Market Mawar berdiri dengan tujuan memberikan kenyamanan kepada masyarakat dalam berbelanja kebutuhan sehari-hari dengan mengambil konsep pasar yang lebih modern. Dimana kebanyakan pada saat itu masyarakat hanya mengandalkan pasar tradisional dan warung-warung terdekat untuk memenuhi kebutuhan sehari-harinya. Penulis menggunakan dua metode penelitian yaitu penelitian lapangan dan penelitian kepustakaan metode pengumpulan data dengan observasi, wawancara dan dokumentasi yang bersumber dari data primer dan data sekunder dan dianalisis dengan uji asumsi klasik, analisis deskriptif kualitatif, dan analisis deskriptif kuantitatif. Kesimpulan dari penelitian ini adalah sikap konsumen dan persepsi konsumen berpengaruh terhadap keputusan pembelian. Hasil tersebut dinyatakan dalam hasil model persamaan Ŷ = 20,454 + 0,674X1 + 0,398X2 yang artinya terdapat pengaruh positif antara sikap konsumen dan persepsi konsumen terhadap keputusan pembelian pada Mini Market Mawar Balimbingan.
Further insights into the operation of the Chinese number system: Competing effects of Arabic and Mandarin number formats
Authors: Quinlan Philip T. , Cohen Dale J. , Liu Xingyu 
Published: July 2020

AbstractHere we report the results of a speeded relative quantity task with Chinese participants. On each trial a single numeral (the probe) was presented and the instructions were to respond as to whether it signified a quantity less than or greater than five (the standard). In separate blocks of trials, the numerals were presented either in Mandarin or in Arabic number formats. In addition to the standard influence of numerical distance, a significant predictor of performance was the degree of physical similarity between the probe and the standard as depicted in Mandarin. Additionally, competing effects of physical similarity, defined in terms of the Arabic number format, were also found. Critically the size of these different effects of physical similarity varied systematically across individuals such that larger effects of one compensated for smaller effects of the other. It is argued that the data favor accounts of processing that assume that different number formats access different format-specific representations of quantities. Moreover, for Chinese participants the default is to translate numerals into a Mandarin format prior to accessing quantity information. The efficacy of this translation process is itself influenced by a competing tendency to carry out a translation into Arabic format.