bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Chemotherapy on the hematological parameters of Acute Myeloid Leukemia Iraqi patients
Authors: S. Resn Noorhan , K. Zedan Zahraa 
Published: February 2025

Background: Acute myeloid leukemia (AML) is characterized as an aggressive blood cancer with rapid growth of immature leukemic cells. AML primarily impacts bone marrow and blood, resulting in alterations in every single hematological parameter that is present in the peripheral circulation. These changes are also observed in most patients following chemotherapy. Objective: This study aims to compare the changes in the hematological parameters of acute myeloid leukemia Iraqi patients before, during, and after chemotherapy treatment to healthy controls. Method: 120 AML cases were studied. Based on the chemotherapy stage, 40 patients were assigned to each group (newly diagnosed, under treatment, and relapsed). Baghdad Teaching Hospital, Iraq, provided the cases and samples from February 2022 to April 2023. This study also included 40 healthy controls. All individuals had peripheral blood drawn. An automatic hematology analyzer counted haemoglubin (HB), White blood cells (WBC), and Platelets (PLT). Results: Results showed that the distribution according to gender revealed that the prevalence of AML was (61.66) % for males and (38.33) %for females. Smoking was also recorded in this study, 57 (47.5%) smoker patients and 63 (52.5%) non-smoker patients, and most of the clinical cases, according to the French-American-British system )FAB(, was in M3 p= (0.0001). The patients' ages ranged from 15 to 75 years old, and thirty-eight cases (31.666%) out of (120) were up to 40 years old. Results showed differences in hematological parameters between the control and AML patients group, before, under treatment, and relapsed, with lower Red blood cells (RBCs), WBCs, Hb, and platelets in the patient's group than the control, the exceptions being made for newly diagnosed and relapsed patients, whose WBC counts were elevated. After chemotherapy, most hematological parameters decreased significantly except PLT, which was higher in the treated patients. Conclusion: AML affects the patient's hematological parameters, making them at abnormal levels, increase or decrease, during different stages of disease and Chemotherapy. WBC, HB, and Platelet count show different levels after Chemotherapy and relapse.
Increasing Local Original Income: Implementation of Tourism Sector Development Policy in Indonesia
Authors: Wahid Nur , Rusliadi Rusliadi , Bahri Andi Iqra Syamsul 
Published: February 2025

If the tourism sector is not well managed, uncontrolled growth and excessive waste can damage the environment and reduce its economic potential. The impact will make it difficult for someone to create jobs. This research aims to analyse the implementation of a tourism development policy in increasing local revenue in Bulukumba Regency. Researchers used qualitative methods, research data obtained from observation, interviews, documentation, and media review. In the data analysis process, researchers used Nvivo 12 plus software. This research indicates that tourism development efforts in Bulukumba have produced positive results. The Tourism Office as the main implementer and the community as a supporter. Government and community involvement in the policy implementation process and establishing strategic programmes. This is evidenced by the communication during the implementation of tourism policies that runs by transmitting information to all stakeholders. The implementation of disposition has shown positive results in terms of optimising human resources. However, the persistence of the problem of overlapping responsibilities in the bureaucratic structure hinders the achievement of optimal performance. This research can contribute to the government to further strengthen cooperation in policy implementation and management of the tourism sector in various regions to improve people's welfare.
Condition of young scientists of cartography in Poland: searching for a diagnosis (2016–2022)
Authors: Słomska-Przech Katarzyna , Zawadzki Mateusz , Stadnicka Maria , Wabiński Jakub , Adolf Albert , Róg Marta , Sompolski Marek 
Published: February 2025

Abstract
The article assesses the condition of cartographic research in the context of young scientists. Based on an analysis of the 469 academic achievements of 77 young Polish cartographers in the 2016–2022 period, the authors highlight challenges in defining contemporary cartography and difficulties in classifying research due to its interdisciplinary nature, overlap with GIS, and the use of cartographic methods in studies from other fields. The study also examines thematic trends, mobility constraints, and patterns of scientific collaboration. The findings emphasise the need to support young researchers and foster interinstitutional cooperation.
Como a automedicação com antibióticos impacta na microbiota do trato gastrointestinal
Authors: Torres Carolina Nunes , Rocha Eduarda Helena Castellanos , Peres Letícia Alves , Melo Maria Clara Vieira de , Allegretti Melissa , Barbosa João de Sousa Pinheiro 
Published: February 2025

Objetivo: Evidenciar de forma clara e objetiva os impactos da automedicação com antibióticos na microbiota do trato gastrointestinal. Métodos: Este artigo utilizou estudos randomizados, abertos e multicêntricos com exposição de indivíduos a antibióticos e grupo placebo com análises fecais, estudos transversais e de triagem com análise do microbioma intestinal, por metagenômica shotgun, de indivíduos que fizeram terapia antimicrobiana e estudo seccional, epidemiológico e quantitativo com entrevistas e aplicação de questionários sobre a automedicação e o uso e conhecimento de antibióticos em uma determinada população. Resultados: Foi observado alterações na microbiota intestinal e em tratamentos contra infecções, disbiose, impactos na resposta imune e inflamatória do corpo, aumento da resistência de bactérias e modificações na estrutura do microbioma. Considerações finais: Conclui-se que a automedicação com antibióticos é predominante na população observada e estudada. Além disso, as consequências desse fenômeno refletem a falta de entendimento sobre a auto-administração de antimicrobianos e seus efeitos metabólicos.
ТЕОРЕТИЧЕСКАЯ МОДЕЛЬ ИННОВАЦИОННОГО ГИПЕРКЛАСТЕРА КАК ФОРМЫ НЕОКЛАСТЕРИЗАЦИИ ПРОИЗВОДСТВА И КОНВЕРГЕНЦИИ ЭКОНОМИЧЕСКОГО ПРОСТРАНСТВА
Authors: Напольских Д.Л. 
Published: February 2025

Предложена гипотеза о возможности рассмотрения инновационных гиперкластеров как новой формы кластерного развития. Обозначены перспективы инновационных гиперкластеров как формы неокластеризации производства и конвергенции экономического пространства России. Определены перспективные направления и проблемы рассмотрения цифрового пространства и экономического времени применительно к разработке теоретической модели гиперкластера. Сформулированы теоретические основы разработки модели инновационного гиперкластера. Определены перспективные направления практического применения модели инновационного гиперкластера в рамках реализации политики экономического развития.
Introduction. The role of innovative clusters as points of economic growth and increase of the connectivity of the country's economic space remains relevant. In this regard, the scientific task of searching for models of formation and technologies for the development of innovative clusters relevant to modern conditions is actualized, due to the significant differentiation of sectoral and spatial conditions of the development of Russian economy. The concept of neoclusterization and the corresponding methodological tools is proposed as a theoretical and methodological basis for optimizing the innovation processes in the context of spatial development of the Russian Federation. The goal of the study is to form the theoretical bases for the development of an innovative hypercluster model as a form of neoclusterization of Russian economy. The objectives of the study are to formulate a scientific problem and identify promising areas of hypercluster research, to develop the bases of a theoretical model of an innovative hypercluster, to identify the key problems in developing a theoretical model of an innovative hypercluster, to determine the main directions of practical application of the innovative hypercluster model. Research methodology. Such general theoretical research methods as abstraction and concretization, analysis and synthesis, induction and deduction, comparison and contrast were used to solve the postulated scientific problems. Conclusion. The hypercluster model has conceptual advantages that allow minimizing the limitations caused by the spatial discontinuity of innovative and industrially developed locations within the economic space of the country. Firstly, the hypercluster model assumes the fullest possible use of the existing industrial and scientific and educational potential of the territories, formation of the closed value chains. Secondly, development of interregional clusters makes it possible to use the existing advantages of scientific and technical cooperation within the macro-region with innovative active leading regions. Thus, the proposed model can be considered as an alternative to the recently quite popular idea for enlarging of Russian regions in order to equalize the level of their socio-economic development.
КОММЕРЦИАЛИЗАЦИЯ УНИКАЛЬНЫХ ТЕХНОЛОГИЧЕСКИХ КОМПЕТЕНЦИЙ КАК ФАКТОР ПОВЫШЕНИЯ ЭФФЕКТИВНОСТИ ПРОИЗВОДСТВА НА ПРЕДПРИЯТИЯХ ОБОРОННО-ПРОМЫШЛЕННОГО КОМПЛЕКСА
Authors: Юрин П.О. , Двоеглазов В.В. , Кушхов А.П. 
Published: February 2025

Статья посвящена исследованию уникальных технологических компетенций АО «Завод полупроводниковых приборов» и их влиянию на экономическую эффективность производства. Проведён анализ хозяйственной деятельности и технологического процесса. Применение сравнительного анализа позволило выявить компетенции технологического превосходства над конкурентами. Комплексный подход позволил сформировать рекомендации к повышению эффективности производства. Выявлены сильные стороны производственного предприятия, на основании которых возможна коммерциализация уникальных технологических компетенций.
Introduction. Today the problem of diversification is of vital importance for Russian defense industry enterprises. Particular role is paid to the output of high-technology products of civilian designation. Military-industrial complex organisations face difficulties when selecting the lines of production development. The reasons are lack of competence in the marketing of civil products, need in high investments with the difficult to forecast results, demand in constant decrease of production costs, no work experience in the highly competitive markets. The goal of the study is to reveal the unique technology competence of the defense industry enterprises for the future commercialization. The АО “Zavod poluprovodnikovykh priborov” (AO “Plant of Semi-Conductor Devices”) was the object of the study. The authors consider that the major unique features of production in this plant are as follows: full technological cycle of metal-and-ceramic case production of any complexity depending on the ordering customer requirements; producing and designing of large batches with the specified characteristics; meeting the desired parameters of outputs with the use of the quality control system. Results. The authors offer to develop the new unique technology competence and new markets with the contract manufacturing promotion on the working equipment or its modernization, including the use of raw materials of Kyosera company. Such cooperation will help the plant to improve its performance. The Japanese manufacture will increase its presence in the markets of Russia and CIS by way of secondary sales. Conclusions: The defense industry enterprises are required to the improvement of efficiency of economic activity without any delay, commercialization of unique technology competence may be the solution of this problem. Identification and analysis of unique technology competence shall be carried out in an integrated manner, modern conjuncture of available technologies in the global market shall be taken into account. The problem of right revealing of unique technology competence will be the key one in the diversification and the strategy for the defense industry enterprises development.
СУЩНОСТНЫЕ ХАРАКТЕРИСТИКИ И ЭФФЕКТИВНОСТЬ ФУНКЦИОНИРОВАНИЯ РЫНКА ПРЕСНОЙ ВОДЫ
Authors: Елагина В.Б. 
Published: February 2025

В статье исследуются сущностные характеристики и тенденции развития рынка пресной воды на основе системного подхода в рамках институционального мейнстрима. Выделены стейкхолдеры национального рынка пресной воды с присущими им потребностями и структура позиционирования их интересов в соответствии с критериями властности, легитимности и срочности. Сформирована модель эффективности функционирования рынка водоресурсных благ в контексте корреляции экономической, социальной и экологической систем.
Introduction. The topicality and relevance of considering fresh water as an economic good stem from the limited nature of the socially significant resource of high utility and value and its low price demand elasticity, which was emphasized by the classical economists. In modern conditions, the growing shortage of fresh water reveals the need to overcome this economic threat associated with negative consequences for both the economy and the social environment and the ecological system. The aim of the work is to study the essential features of the fresh water market as a supplier of a socially significant irreplaceable good and apply a multidimensional approach to determining its efficiency. The institutionalization of the fresh water market as a supplier of essential goods was organized by identifying the formal and informal structures that describe the interaction of supply and demand, price regulation, the competitive mechanism, the stereotype of water consumption, etc. Methods. The paper considers approaches to determining the cost of fresh water based on the marginal productivity theory, water rent, Pareto optimum, tariff differentiation, etc. The analysis of the essential characteristics of the fresh water market has led to the conclusion that the availability of this good is a key factor in economic development. This determines the need to use the achievements of the Fourth Industrial Revolution to improve the efficiency of water use and water consumption. As a result of identifying stakeholders in the fresh water market and taking into account their interests in the context of Mitchell's theory, it has been revealed that a large proportion of the stakeholders are highly interested in satisfying their needs and socially informed for rational decision making, but have a limited set of tools to influence the market development trajectory due to the imperfection of the institutional environment. Results. The stakeholders’ activities will have a positive impact, provided their efforts are joined into collective actions, and information asymmetry and institutional barriers are reduced. The efficiency of the use of fresh water resources is considered in the correlation of the economy with the society and the ecological environment; the multiplier effect of this interaction is highlighted, the importance of taking into account the "water footprint", as well as the use of lean technologies and artificial intelligence systems are emphasized.
АНАЛИТИКА РАЗВИТИЯ РЫНКА ЭЛЕКТРОТРАНСПОРТА В РОССИИ
Authors: Мубаракшина Р.Р. , Валеева Ю.С. 
Published: February 2025

В статье рассмотрены вопросы развития рынка электротранспорта в России. Были исследованы факторы, влияющие на тенденцию развития в транспортной инфраструктуре, а также приведены несколько препятствий, которые не позволяют эффективно реализовывать современный транспорт передвижения. Проведён опрос среди населения нашей страны. По результатам их ответов был сделан вывод о дальнейшем продвижении производства электротранспорта.
Introduction. Progress in the transport sector development is imminent; technologies are evolving, new projects and start-ups are being implemented that help bring improvements not only to people’s lives, but also to the quality of their environment. The goal of the study is to explore the readiness of the population for electric vehicle transition and investigate the prospects for the development of the electric vehicle market in Russia. Methods. To study the market for electric vehicles, a survey was conducted using a Google form. The authors developed a questionnaire that included twelve questions. 138 people participated in the survey; the sample was made up of faculty members and university students. Results. A critical analysis of the works on the topic has shown that studies of consumer intentions are largely focused on product features and social factors of the purchase. Three types of characteristics contribute to the adoption of electric vehicles: customers’ personality traits, product attributes, and situations. Customer personalities make an impact on their buying behaviors. Skepticism, or lack of it, about electric cars could limit their commercial success. Low-carbon policies and environmental attitudes influence consumer purchasing decisions. If no restrictions apply to electric vehicles and government strategies are well understood, customers are more likely to purchase electric cars. The factors affecting the decision to buy electric vehicles are their price and quality. Conclusion. The study showed that the majority of respondents were ready to switch fully to electric vehicles. More than 50% of respondents demonstrated a positive attitude towards electric vehicles and viewed them as the transport of the future.
СОВЕРШЕНСТВОВАНИЕ МЕХАНИЗМА УПРАВЛЕНИЯ КАЧЕСТВОМ ОБРАЗОВАТЕЛЬНЫХ УСЛУГ В СИСТЕМЕ ВЫСШЕГО ОБРАЗОВАНИЯ
Authors: Категорская Т.П. 
Published: February 2025

В статье представлен обзор основных проблем в области оценки качества образовательных услуг в системе высшего образования, анализ которых послужил основанием для разработки методики оценки качества образовательных услуг. Предложенная автором методика сформирована на базе интеграции компетентностного и субъектного подходов, что обеспечивает комплексность оценки качества. Совершенствование механизма управления качеством образовательных услуг базируется на внедрении авторской методики в существующий механизм, что в свою очередь обеспечит повышение уровня качества образовательных услуг в системе высшего образования.
Introduction. The system of higher education is the linchpin in building up the labour potential and meeting the needs of the national labour market. The purpose of the study is to improve the quality management mechanism for educational services by introducing in it a methodology developed by the author. The methodology is based on the integration of the competency-based and subjective approaches. Results. The author has developed and proposed a methodology for assessing the quality of educational services in higher education, which allows for a comprehensive assessment of the quality of educational services. The integration of the subjective and competency-based approaches in the quality assessment methodology enables quantitative and qualitative assessments of the quality of educational services from the perspectives of key stakeholders of the market of educational services. The presence of the subjective approach in the methodology is necessitated by the fact that the notion of quality of educational services differs significantly in its content for each subject of the educational services market (universities, employers, households). The competency-based approach aims to assess the level of formation of students’ specific competencies, i.e. to assess the quality of the result of the implementation of educational services (educational process). Conclusion. Through its impacts on the groups of endogenous factors that have a dominant influence on the quality of educational services, as well as by monitoring the effectiveness of these impacts using the proposed quality assessment methodology and the system of indicators contained in it, the university will be able to exert a significant effect on improving the quality of educational services in the higher education system. Practical significance. The methodology proposed by the author can be integrated into the existing quality management mechanism for educational services in the higher education system without introducing any fundamental changes to the mechanism structure through expanding the functions of the education department.
Михайло Косач як персонаж публіцистики Олени Пчілки (до питання рольових псевдонімів)
Authors: Моклиця Марія 
Published: February 2025

The article talks about Olena Pchilka‘s pseudonyms recorded in dictionaries, as well as unidentified as an object for a separate study.
The purpose of the article is to outline phenomenology as an object of literary research pseudonyms in Olena Pchilka‘s work in general, in journalism in particular.Achieving this aim requires a combination of methodological approaches: cultural-historical and cultural-sophistic (context of the era, cultural and social mission of the author), psychoanalytical (game in process creativity), metadramatic (“role in role” parameters), linguistic (onomastic aspect of pseudonyms), and structuralist (binary role distribution).
Results. In the process of creativity of artists of the 20th century dominate reflectionand conscious playing internal conflicts, and therefore the specificity of the creative process is determined by the game (in the deepest origins, sublimation equals game), and it becomes a special identifier of the author‘s style of dramatization of all genres and types of creative activity. In the article, it is proposed to do this for the first time writer‘s pseudonyms as a separate object of research, with the involvement of a number of modern ones methodologies. It is suggested in the study of writer‘s pseudonyms to turn to acting experience to use pseudonyms and roles. Several theses are offered for expression of thephenomenology of writer‘s pseudonyms. The theses are confirmed by the analysis of two unidentified pseudonyms of Olga Kosach-Dragomanova – Mykhailo Zakhidny and Mykhailo Slobidsky, which appeared in the “Vestniki zemskikh Hadiatsky” in 1917 under her editorship. Conclusions. An important aspect of these two pseudonyms is their clearly emphasized binary (common name, semantically antonymous surnames). This is the embodiment of critical thinking of Olena Pchilka and at the same time of her political foresight. In addition to the main female role, specified in the most known by her pseudonym, Olena Pchilka also created a number of male roles.