bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dysregulated hepcidin response to dietary iron in male mice with reduced Gnpat expression
Authors: Rishi Gautam , Secondes Eriza S. , Asplett Kiran , Wallace Daniel F. , Ostini Lesa , Berger Johannes , Subramaniam V. Nathan 
Published: August 2020

Abstract
Exome sequencing has identified the glyceronephosphate O-acyltransferase (GNPAT) gene as a genetic modifier of iron overload in hereditary hemochromatosis (HH). Subjects with HFE (Homeostatic Iron Regulator) p.C282Y mutations and the GNPAT p.D519G variant had more iron loading compared with subjects without the GNPAT variant. In response to an oral iron challenge, women with GNPAT polymorphisms loaded more iron as compared with women without polymorphisms, reinforcing a role for GNPAT in iron homeostasis. The aim of the present study was to develop and characterize an animal model of disease to further our understanding of genetic modifiers, and in particular the role of GNPAT in iron homeostasis. We generated an Hfe/Gnpat mouse model reminiscent of the patients previously studied and studied these mice for up to 26 weeks. We also examined the effect of dietary iron loading on mice with reduced Gnpat expression. Gnpat heterozygosity in Hfe knockout mice does not play a role in systemic iron homeostasis; Gnpat+/− mice fed a high-iron diet, however, had lower hepatic hepcidin (HAMP) mRNA expression, whereas they have significantly higher serum iron levels and transferrin saturation compared with wildtype (WT) littermates on a similar diet. These results reinforce an independent role of GNPAT in systemic iron homeostasis, reproducing in an animal model, the observations in women with GNPAT polymorphisms subjected to an iron tolerance test.
The Role of Voice Quality in Mandarin Sarcastic Speech: An Acoustic and Electroglottographic Study
Authors: Li Shanpeng , Gu Wentao , Liu Lei , Tang Ping 
Published: August 2020

PurposeSarcasm is a specialized speech act in daily vocal communication usually characterized by unique prosodic features, but the role of voice quality in expressing sarcasm has not been explored much. The goal of this study is to explore the voice quality features of Mandarin sarcastic speech in comparison to sincere speech.MethodFifteen male and 15 female native speakers of Mandarin uttered 31 target sentences with both sincere and sarcastic attitudes. Nine voice quality parameters extracted from the acoustic and electroglottographic signals were analyzed using a linear mixed model, and a classification analysis using a random forest algorithm was conducted to identify the relative contribution of these parameters to the differentiation between sincere and sarcastic utterances.ResultsIn comparison to sincere speech, sarcastic speech had a creakier voice, which was characterized by a lower fundamental frequency, a greater degree of vocal fold adduction (i.e., higher contact quotient), lesser noise (i.e., higher harmonics-to-noise ratio), and more multiple pulsing (i.e., higher subharmonic-to-harmonic ratio). The interaction effect revealed a gender difference in the use of creakier voice to express sarcasm in Mandarin. The classification analysis using the random forest algorithm showed that the nine voice quality parameters resulted in 84.0% and 83.7% identification rates for sarcastic and sincere utterances, respectively.ConclusionsThe results of this preliminary study support the role of voice quality in expressing sarcasm in Mandarin speech. Using a set of voice quality parameters, sarcastic and sincere utterances can be effectively identified. Furthermore, there is a gender difference in the use of creakier voice in expressing Mandarin sarcastic speech.Supplemental Materialhttps://doi.org/10.23641/asha.12743780
BIPM comparison BIPM.RI(II)-K1.Ge-68 of activity measurements of the radionuclide 68Ge for the LNMRI/IRD, NIST, NIM, IRA-METAS, LNE-LNHB and the TAEK, and the linked 2015 CCRI(II)-K2.Ge-68 comparison
Authors: Michotte C , Ratel G , Courte S , Nonis M , Iwahara A , Da Silva C J , Fitzgerald R , Bergeron D E , Cessna J T , Laureano-Pérez L , Pibida L , Zimmerman B E , Zhang M , Liang J , Liu H , Juget F , Nedjadi Y , Fréchou C , Bobin C , Yeltepe E , Dirican A 
Published: August 2020

This report summarises the results for the new BIPM.RI(II)-K1.Ge-68 comparison. Six metrology institutes have participated, enabling the first value of the key comparison reference value(KCRV) to be determined. The KCRV was calculated using the power-moderated weighted mean and the results. A link has been made to the CCRI(II)-K2.Ge-68 comparison held in 2015 through the NIST, NIM,IRA-METAS and the LNE-LNHB who participated in both comparisons. One NMI used the K2 comparison to update their degree of equivalence. The degrees of equivalence between each equivalent activity measured in the International Reference System (SIR) and the KCRV have been calculated and the results are given in the form of a table for the remaining five NMIs in the BIPM.RI(II)-K1.Ge-68 comparison and the 12 other participants in the CCRI(II)-K2.Ge-68 comparison. A graphical presentation is also given.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
A statistical approach towards defining national-scale meteorological droughts in India using crop data
Authors: Udmale Parmeshwar , Ichikawa Yutaka , Ning Shaowei , Shrestha Sangam , Pal Indrajit 
Published: August 2020

Abstract
In recent years, several drought indices have been developed and used to monitor local to regional scale droughts on various temporal scales. However, to our knowledge, these indices do not possess generalized criteria to define a threshold in which to declare a national-scale drought. We present a statistical methodology to identify national-scale meteorological drought years in India. We implement a Superposed Epoch Analysis and bootstrap analysis to estimate annual cereal crop production losses as a result of widespread meteorological drought events. For this purpose, the meteorological definition of drought based on the Standardized Precipitation Index (SPI) and Standardized Precipitation Evapotranspiration Index (SPEI), in combination with the country’s cropland area and cereal crops production, is used. The results demonstrate that a national-scale meteorological drought is defined if approximately 19% or more of India’s cropland is affected by meteorological drought (SPI3 and SPEI3 equal to or less than −1.00) throughout the monsoon season (June–September). According to this analysis, depending on the indicator data used, a total of 18to 20 national-scale meteorological droughts were identified in India during 1964–2015, causing a 3.61% to 3.93% composite decrease in cereal crops production. The years which were commonly identified as national scale meteorological droughts over cropland by using different approaches are 1965, 1972, 1987, 2002, and 2009. A similar statistical approach can also be used to define drought thresholds at various spatial scales using the drought indices most applicable to the purpose and scale of study.
Classical and quantum complex Hamiltonian curl forces
Authors: Berry M V 
Published: August 2020

Abstract
A class of Newtonian forces, determining the acceleration
F
(x, y) of particles in the plane, is
F
=(Re F(z), Im F(z)), where z is the complex variable x + iy. Curl
F
is non-zero, so these forces are nonconservative. These complex curl forces correspond to completely integrable Hamiltonians that are anisotropic in the momenta, separable in z and z
* but not in x and y if the curl is nonzero. The Hamiltonians can be quantised, leading to unfamiliar wavefunctions, even for the (non-curl) isotropic harmonic oscillator. The formalism provides an alternative interpretation of the analytic continuation of one-dimensional real Hamiltonian particle dynamics, where trajectories are known to exhibit intricate structure (though not chaos), and is a Hermitian alternative to non-Hermitian quantisation.
Prediction of size reduction by batch ball milling process for crab shell powder prior hydroxyapatite conversion
Authors: Wibisono Yusuf , Rafianto Vibi , Alvianto Dikianur , Bagus Hermanto Mochamad 
Published: August 2020

Abstract
The crab (Portunus pelagicus) shell is a marine biowaste produced by seafood industries. Traditionally, crab shells were collected to be converted into animal feed, however many of them are disposed of as industrial waste. A conversion of crab shells into hydroxyapatite is a better option for producing high-value biomaterial. Hydroxyapatite materials can be used as slow-release fertilizer while combining them with traditional fertilizer or as a stand-alone green fertilizer with high phosphatic content. Prior to hydroxyapatite conversion, the size reduction of crab shells is required. In this study, crab shell powder is derived from dried crab shell with the water content is approximately 10% wb. The size reduction is processed by using a customized batch type ball mill. This study is aiming at determining the kinetic model of milling parameters for crab shell milling by using the ball mills. An amount of 1.5 kg of dried crabs shell was milled by using 3-size mixed metal balls. The powder was then analyzed its particle size, and the particle size is used as an input in the mathematical model. The computational study focused on the calculation of optimal rotational velocity and kinetic model during the milling process. The kinetic model was based on Population Balance Equation of the mass balance principle, and the results are compared with experimented data characterized by particle size analyzer. It is observed that there are discrepancies between the model and experimental data due to the characteristic of raw materials; however the kinetic model can be used as a prediction of particle size reduction using the ball mill without conducting the real experiment.
Aloe vera and beeswax based coating to maintain shelf life of salak cv. Madu
Authors: Sari P R P , Darmawati E , Ahmad U 
Published: August 2020

Abstract
The coatings on fruits after harvested was applied to maintain the appearance and quality up to the consumer’s hands. This study aimed to maintain color and reduce the level of decay of salak madu during storage. Salak madu was obtained from Madding Fresh, trader and supplier salak from Sleman, Yogyakarta. The salak was coated with Aloe vera gel (20% and 50%) and beeswax (3, 6, and 10%). All samples were stored at 25–28 °C. The parameters used to measure the effect of treatment are skin color, percentage of decay, and weight loss. Observations were carried out for 12 days. The results of this study were found that dyeing on a coating made from Aloe vera 50% was able to slow down weight loss and percentage of decay until the 6 days, while Aloe vera 30% was better at maintaining color changes during storage. Beeswax 3% coating can slow down discoloration and percentage of decay until 6 days of storage. Long-term storage (12 days) with beeswax 10% was better in maintaining changes in the quality of salak madu, while for short-term storage (6 days), beeswax 3% gives better results.
Development of calibration model for determination of sweeteners additives in Indonesia rice flour-based food by FT-NIR spectroscopy
Authors: Masithoh R E , Rondonuwu F F , Setyabudi F M C S , Cho B K 
Published: August 2020

Abstract
Cane sugar and other artificial sweeteners are usually used as a food additive to provide sweetness in food. Sweetener additives can be consumed safely by considering the acceptable daily intake (ADI). This research was aimed to determine the type of sweeteners and the level of sweeteners added in food with regard to the ADI. The food sample used in this study was geplak, traditional Indonesian food, made of rice flour, coconut, and sugar, or other sweeteners. The reflectance of geplak powder was measured using the NIRFlex N500 Fiber Optic Solids Cell at 4000 – 10,000 cm-1. The reflectance spectra obtained were pre-treated and analyzed using The Matlab version R2018a. Principal component analysis (PCA) and partial least square discriminant analysis (PLS-DA) were used for data exploration and qualitative classification. PCA model was able to classify food added with sugar, saccharin, and cyclamate. PLS-DA calibration model using the 2nd derivative Savitzky-Golay as the spectral pretreatment achieved 100% accuracy in predicting high sucrose and high saccharin, as well as low cyclamate and low saccharin, while achieved a slightly low accuracy of 90.0 and 85.7% in predicting low sucrose and high cyclamate, respectively. PLS-DA prediction model, which also applies the 2nd derivative Savitzky-Golay pretreatment spectra, achieved 100% accuracy in predicting high and low sucrose, low cyclamate, and high saccharin.
Effect of different threshing methods on the physical characteristics of two varieties of paddy rice
Authors: Krah C Y , Kumah P , Mardjan S , Njume A C 
Published: August 2020

Abstract
As part of the efforts to reduce the postharvest losses (quantity and quality) of rice, this study was carried out to ascertain the effects of three threshing methods: (stone, bambam (wooden box), and combine harvester) on two varieties of rice: AGRA and Jasmine 85. The experimental design was a 2×3 factorial experiment in Completely Randomized Design (CRD) with three replications. At the end of the study, the result of the parameters measured shows combine harvester threshing method recorded the highest dockage level (0.41%) while bambam produced the cleanest grains with dockage level of 0.22%. Percent immature grains produced by AGRA (1.02%) was significantly higher than that of Jasmine 85 (0.61%). Threshing by the stone method produced the highest amount of fissured grains (3.8%) whiles combine harvester produced the least (3.14%) fissured grains. In the germination test, Jasmine 85 (86.11%) were geminated significantly better than AGRA (63.88%). In terms of grain weight, Jasmine recorded a higher weight (25.783g) than AGRA (25.197g), suggesting a higher carbohydrate stored in Jasmine 85. It could be concluded that different varieties have different internal and external properties hence respond differently to a postharvest treatment.
Effect of particle size of white pepper to yield and quality of oleoresin produced by using an ultrasonic-assisted extraction method
Authors: Budiastra I W , Damanik AP , Akbar MTF 
Published: August 2020

Abstract
The purpose of this study was to examine the effect of particle size of white pepper to yield and quality of oleoresin produced using Ultrasonic Assisted Extraction (UAE) method. White pepper from Bangka Belitung and South Sulawesi were ground using a milling machine and sifted to produce white pepper powder with a particle size of 30, 60, and 100 mesh. The samples (200 g each) were dissolved in ethanol (1:4) and subjected to UAE method to obtain oleoresin. The UAE was carried out using an ultrasound frequency of 20 kHz and an amplitude of 90% for 75 minutes. For comparison, the maceration extraction method was applied for 7 hours. The product of oleoresin was then subjected to vacuum evaporation to reduce ethanol solvent. The yield of oleoresin was calculated and the quality of oleoresin such color and piperine content was measured using colorimeter and GCMS, respectively. The results show that the particle size significantly affects the yield of oleoresin. The smallest particle size (100 mesh) gives the highest yield of oleoresin. The yield of oleoresin produced by UAE was not significantly different from maceration. The UAE method produced higher piperine content (7.51-11.91%) than the maceration extraction method (3.08-8.02%). The color of oleoresin produced by UAE method was similar to maceration.
Thermal Efficiency Simulation of Working Fluids Performance on Small Scale Organic Rankine Cycle (ORC) with Biomass Energy
Authors: Sucahyo L , Yulianto M , Hartulistiyoso E , Faza I 
Published: August 2020

Abstract
This paper presents the comparative analysis of working fluids R-134a, R-414B, R-404A, and R-407C on small scale Organic Rankine Cycle (ORC) with biomass of coconut shell as heat energy. Simulation of the close system using Cycle Tempo software and compared with mathematical calculation models using Engineering Equation Solver (EES) software. The property of working fluids is obtained by using Reference Fluid Properties (REFPROP). The best result performance of ORC was shown by working fluid R-404A with thermal efficiency ranges between 7.48-7.53% and electric power output range between 0.074-0.091 kW. This condition operated on the turbine inlet temperature at 60 °C, difference turbine working temperature of 15 °C, condensing temperature of 25 °C, and water boiler mass flow rate of 3 lpm. A comparison of thermal efficiency simulated by Cycles Tempo and EES has an average coefficient of determination (R2) is 99.20%.
Steady state simulation on combination of glazed and unglazed flat plate solar collectors for air heating
Authors: Nelwan L O , Wulandani D , Subrata I D M , Effendi R 
Published: August 2020

Abstract
Unglazed flat plate solar collectors usually have lower costs and can have an advantage in situations where heat loss is low. In this study a steady state simulation of the combination of glazed and unglazed flat plate solar collectors for air heating was performed for various conditions of heat transfer coefficient (3, 12 and 21 W/m2-°C), inlet temperature (30, 45, 60 and 75°C) and solar irradiation (350, 600 and 850 W/m2). The efficiency of combined system of the glazed and unglazed solar collector area was better compared to the system which consists entirely of glazed at a low coefficient of heat transfer (3 W/m2-°C), except for high inlet temperature (more than 60°C) and low solar irradiation (350 W/m2-°C). For the combination of 6m2 unglazed and 9m2 glazed solar collector, the higher percentage of flow rate through unglazed collector slightly increases efficiency except at high inlet temperatures (> 60°C) for high heat transfer coefficient (12 and 21 W/m2-°C) and at low solar irradiation (350 W/m2). For air heating operations which are maintained in equilibrium conditions the temperatures of the air produced were slightly higher than that of the collector inlet.
IDN-LCI: The conceptual framework of the Indonesian life cycle inventory database to support the life cycle assessment
Authors: Siregar Kiman , Supriyanto  , Setiawan Arief Ameir Rahman , Wiloso Edi Iswanto , Sholihati  , Miharza Try , Sofia Intan 
Published: August 2020

Abstract
Divers economic activities in Indonesia such as agriculture, plantation, industry, forestry, industry, constructions, civil, property, and others have been affecting the environment. Assessment of the environmental impact was critical to reduce the damage to the environment and to ensure production and market sustainability. Life Cycle Assessment (LCA) was the popular method in the environmental analysis based on the ISO 1440 and 14044 that consist of activities such as (1) goal and scope definition, (2) life cycle inventory, (3) inventory analysis, (4) impact assessment and interpretations. More than 40 years LCA has been established. However, the most problem occurred was the availability of Life Cycle Inventories (LCI) database. 70-80 % time and cost in LCA analysis are the data collection and inventory analysis. In this research, we proposed the Indonesian LCI Database. The result of this study was a conceptual framework, actor analysis of Indonesian LCI Databases. The result of this study was the theoretical framework that integrated stakeholder participation, such as academic, business, government, and society. Also, the technical standard and the role of the stakeholder for Indonesian life cycle inventory was designed.
Design of an updraft gasification stove and its performance test with cassava peel as fuel
Authors: Andika S , Nelwan L O 
Published: August 2020

Abstract
In this study, an insulated updraft gasification stove for biomass has been designed and tested for cassava peel. The main components of the stove were forced airflow inlet, biomass bed and gasification chamber and ceramic wool-insulated stainless steel wall. Top lit method was used in the ignition and testing was performed by using water boiling test method. Cassava peel was fed at four levels of bulk densities and moisture content. The result showed that combustion rates were quite high. The bulk density of fuel tend to reduce the rate of combustion and ignition front speed. The cassava peel with moisture content of 8-10% showed reddish-purple flame and small amount of smoke produced while with moisture content above 15%, the fuel could not be ignited in a reasonable time. The thermal system efficiencies of this gasification stove were still quite low, which were between 5.88 to 8.79%.
Application of GeoWEPP - TOPAZ model to delineate stream network and watershed at upper Citarum watershed - Cikeruh and Citarik sub-watershed
Authors: Amaru K , Dwiratna S 
Published: August 2020

Abstract
GIS technology in GeoWEPP, namely TOPAZ model, was utilized to delineate network streams and watershed. The purpose of this study is to apply the TOPAZ model in GeoWEPP for watershed modeling. The research location is the Citarik and Cikeruh Sub-watershed. The TOPAZ model utilizes a DEM to generate topographic parameterization. It processed a DEM and then distinguished a hillslope, a channel based on channel network. Stream order is allocated for channel section in accordance with the watershed channel network. DEMNAS which based on the IFSAR, TERRASAR X, and ALOS-PALSAR was utilized. Network stream and watershed delineation generated by TOPAZ based on 10-meters resolution DEM, 5 ha Critical Source Area (CSA), and 100 meters Minimum Source Channel Length (MSCL). The result shows that GeoWEPP can effectively produce watershed. Compared to the traditional method of delineating by hands, GeoWEPP failed to accurately define the watershed area since it located in the downstream and paddy field. These are weaknesses in the spatial analysis of GIS since TOPAZ cannot define the existing channel and change topography easily. The solution, field surveys are needed and river basins can be accurately determined. However, TOPAZ successfully generates network streams and watersheds in the upstream area.
Evaluation of the sand trap performance of the Pengasih weir during the operational period
Authors: Pradipta AG , Maulana AF , Murtiningrum  , Arif SS , Tirtalistyani R 
Published: August 2020

Abstract
Sedimentation is the main trigger in reducing the capacity of the irrigation channel. The weir is equipped with a sand trap, to withstand the volume of sediments originating from the upstream area, some of which enter the irrigation intake. The sand trap is designed with sufficient width and sloping energy slope, allowing sediment to settle. The Pengasih Weir, located in Kulonprogo Regency, is one of the weirs that is equipped with a sand trap building. The Pengasih Weir and the sand trap were built-in 1972. With the development of current conditions, it is necessary to evaluate the performance of the sand trap of The Pengasih Weir. In this study, the evaluation of sand trap performance is reviewed during the operational (settling) period. The result showed that the Meyer-Peter Muller formula can be used as an approach in the calculation of the amount of sediment transport and also to estimate the settled volume. It is recommended to flush the sand trap in between 184.922 days. The average value of trap efficiency was 0.89%. It can be concluded that the Pegasih Weir sand trap design still has good performance in settling the sediment inflow.