bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
Authors: Ok Mahmut , Yildiz Ramazan , Hatipoglu Fatih , Baspinar Nuri , Ider Merve , Üney Kamil , Ertürk Alper , Durgut Murat K. , Terzi Funda 
Published: January 2020

Abstract

OBJECTIVE
To evaluate the usefulness of intestinal biomarkers in determining the presence of intestinal epithelial damage in neonatal calves with diarrhea caused by 4 etiologic agents.

ANIMALS
40 neonatal calves that were healthy (n = 10) or had diarrhea (30).

PROCEDURES
The study was a cross-sectional study. Results of hematologic analyses and serum concentrations of intestinal fatty acid–binding protein (I-FABP), liver fatty acid–binding protein (L-FABP), trefoil factor 3 (TFF-3), Claudin-3 (CLDN-3), γ-enteric smooth muscle actin (ACTG2), intestinal alkaline phosphatase (IAP), interleukin-8 (IL-8), platelet-activating factor (PAF), and leptin (LP) were compared among calves grouped according to whether they were healthy (control group; G-1) or had diarrhea caused by K99 Escherichia coli (G-2; n = 10), bovine rota- or coronavirus (G-3; 5 each), or Cryptosporidium spp (G-4; 10).

RESULTS
Across the 3 time points at which blood samples were obtained and evaluated, the groups of calves with diarrhea generally had markedly higher mean serum concentrations of L-FABP, TFF-3, IAP, IL-8, and LP, compared with the control group. In addition, G-2 also consistently had markedly higher mean serum concentrations of I-FAB and ACTG2 and lower mean serum concentrations of CLDN-3, compared with the control group.

CONCLUSIONS AND CLINICAL RELEVANCE
Results indicated that degree of intestinal epithelial damage differed among calves grouped by the etiologic agent of diarrhea and that such damage might have been more severe in calves with diarrhea caused by K99 E coli. Additionally, our results indicated that serum concentrations of I-FABP, L-FABP, TFF-3, IAP, IL-8, ACTG2, LP, and CLDN-3 were useful biomarkers of intestinal epithelial damage in calves of the present study.
Liberal Order «Free Riders»: International Development Agenda and the Symbolic Policies of the Rising Powers
Authors: Makarycheva A. V. , Silaev N. Yu. , Danilin I. V. , Chekov A. D. , Shavlay E. P. , Stolyarova S. A. 
Published: January 2020

The West is concerned over the crisis of the liberal world order attributing it to the conduct of emerging powers, such as China, India and Russia. Are its concerns legitimate? Drawing on social identity theory, the authors analyze the emerging powers’ stances on international development through the lens of status dynamics. In particular, three issue areas are investigated: the debate over the UN development agenda, which has revealed differences between Western and non-Western approaches, the changes in the membership of donor and recipient groups over the last decade and the discourse of emerging countries concerning science and technology, which betrays their self-image of a “developed” or “laggard” state.The key finding of the paper is that the crisis of the liberal world order as a set of institutions created by the US-led countries after WWII manifests itself in the distorting symbolic exchange between developed and developing countries. The emerging states are unwilling to recognize the authority of the West and its leadership in setting the direction of global development. Meanwhile, they are trying to gain the status of development front-runners using their own foreign aid programs and science and technology development strategies. However, the rising states are not uniform and consistent in posing a symbolic challenge to the liberal order – while the Russia is striving for a “developed non-western country” status (thereby copying the USSR’s image), India and China, though to different degrees, are positioning themselves both as developed industrial states and as developing countries which receive aid packages from richer members of the international community. What leads to the distortions in this symbolic exchange is the desire of some emerging powers to use the resources of the West and reap the benefits of the world order created by it while denying it a high status. Thus, a classic economic “free-rider problem” arises in international relations: while benefiting from the liberal order created by the West, the rising states do not recognize the status it ascribes itself ignoring the symbolic hierarchy which, as viewed by western countries, underlies this order.The authors declare the absence of conflict of interest.
Euro-Atlantic Security in U.S.-EURussia Triangle and Trump Factor
Authors: Panyuzheva M. M. 
Published: January 2020

The article discusses the security relations among the United States, the EU and Russia in the context of Donald Trump's populism, the change of Western political elites and the erosion of arms treaty regimes. The purpose of the article is to analyze the current state and identify the probable scenarios of relations in the triangle of the USA – the EU – Russia. The article explores the features of the Euro-Atlantic security system from 1990’s till the mid-2000’s; the concept of Euro-Atlantic security in 2008-2009; the US, the EU and Russia relations under Barak Obama and Donald Trump. As a result of a comprehensive analysis, the author comes to the following conclusions: 1) the concept of Euro-Atlantic security is still relevant. Since the NATO based security arrangements are not stabile, security interaction among the USA, the EU and Russia is growing in importance. 2) European leaders seem to be moving towards building a new security architecture and a more balanced dialogue with Russia. The EU remains the main economic partner of the Russian Federation. 3) Trump's “transactional” approach has prompted Europeans to strengthen its defense identity and seek a compromise with Russia. 4) In a multipolar world, the Euro-Atlantic regional security is no longer closed to transatlantic ties. It is important to rethink the concept towards cooperation with non-regional countries. 5) The complex game of engagement and deterrence is likely to continue in relations between Russia and the West. The more uncertain the transatlantic relations become, the more the EU and the US need Russia.The author declares absence of conflict of interests.
Problems and contradictions of international migration statistics
Authors: Loginov B. B. 
Published: January 2020

Analysis of problems and trends in the field of international migration development is impossible without reliable statistical data. Particular economic importance for any country including Russia are data on the flows of labor migrants, which have a great impact on the domestic labor market, gross domestic product, balance of payments. International organizations, including United Nations bodies, haven’t worked out single recommendations on proceeding migration statistics, stratification of migration flows. The universal worldwide technique with border and internal migrant calculation principles regarding flows and stocks of labor migrants is absent at the moment.The author focuses on key discrepancies of national migration statistics in different countries and widely practiced flexible interpretation of it by Western politicians and mass media, therefore, the acuteness of migration problems in the Western countries (first, in the European Union) is overestimated and, on the contrary, migration difficulties of such countries as Russia, Iran, Turkey are downgraded or fully ignored. The difficulties in the calculation of international migration, arising from the ambiguous interpretation of the concept of “migrant”, have been indicated. Three approaches – residence outside the country of birth, citizenship, place of usual daily rest – often conflict with each other, when it is necessary to establish the true country of origin of the migrant.The shortcomings of the main sources of information about immigrants: population census, administrative records, population surveys have been also analyzed in the article. New phenomena in international migration flows, such as “cross-motivation” of migrants and migration without going abroad, require their understanding.
Isolation and Characterization of Commercial Probiotics
Authors: Kolli Guna Ranjan  , Girija Sankar G  , Satyanarayana Raju D V V  
Published: January 2020

Commercial probiotics have bacteria which offer scope for specific treatment as a probiotic against diarrhoea, boosting immune response and relieving stress. Research in probiotics and aquaculture has been done to promote sustainable aquaculture. Studies on microbial ecology in aquaculture and their benefits on human systems are to be assessed. Hence, the present study was aimed at the isolation and characterization of these bacteria obtained from various commercial probiotics. The commercial probiotic samples were collected for isolation using MRS agar. The colonies were selected on the basis of colonial morphology. Isolates were put through cell morphology, physiology and different biochemical tests. Probiotic sample confirmation was done using 16srRNA molecular technique. MEGA7 was used to conduct phylogenetic evolutionary analysis and tabulate a distance matrix. In results, the isolates manifested non-identical growth patterns at dissimilar conc. of NaCl (2.0,4.0 and 6.5) oxygen and at different temperatures (150C, 300C and 450C). On the basis of sugar utilization, physiological testing, biochemical characterization and genetic identification tests, all isolates were established to different species of Lactobacillus rhamnosus, Pediococcus acidilactici and Lactobacillus Plantarum. A systematic protocol was done to identify, characterize probiotic samples and identify them by genetic analysis. Probiotic use is carefully assessed by regulations
Phytopharmacological and Antioxidant Analysis of Hydroethanolic Extract of Boerhavia diffusa
Authors: Murugan K  , Kalaivani P  , Vanitha V  , Bothiraj K.V.  
Published: January 2020

Boerhavia diffusa, a well-known ethno-medicinal plant and were found in tropics and sub-tropics. Boerhavia diffusa is a traditional medicinal plant and they can cure many human ailments. It has most promising pharmacological activities include antifibrinolytic, immunosuppressive, diuretic, hepatoprotective, antidiabetic, anti-inflammatory, anticancer, immunomodulatory, antilympho proliferative, analgesic properties and also for the treatment of pulmonary tuberculosis. Due to their adverse side effects, the naturally occurring antioxidants has increased and replaced by the synthetic antioxidants. This study is focussed on the phytochemical evaluation and in vitro antioxidant activity of Hydroethanolic extract of Boerhavia diffusa. The qualitative chemical test exhibited the presence of phytocompounds like flavonoids, polyphenols, anthocyanins, coumarin, steroids, terpenoids, triterpenoids, glycosides, emodins and saponins. Quantitative analysis of total phenol, total flavonoid and total tannin was found to be 205.25mg/g, 121.65 mg/g and 61.41mg/g. DPPH, Total antioxidant activity, Superoxide anion radical, Nitric oxide and Hydroxy radical scavenging assay showed that B.diffusa was an excellent scavenger of these radicals. These results are an indication of the potent antioxidant property of the extract and may be responsible for some of the therapeutic uses of Boerhavia diffusa.
FUNGSI STRUKTURAL DAN ARSITEKTURAL PADA KONSTRUKSI BAMBU BANGUNAN AMFITEATER TAMAN BUAH MEKARSARI
Authors: Julya ; Anastasia Maurina Sharon 
Published: January 2020

Abstrak- Struktur pada bangunan merupakan hal yang penting dan mendasar untuk mewujudkan terbangunnya sebuah bangunan dalam arsitektur. Penentuan sistem struktur bangunan terkait jenis material tertentu yang dapat memampukan struktur bangunan menanggung beban dan mendukung bentuk bangunan serta sistem bangunan. Salah satu material lokal yang dimiliki oleh negara Indonesia dan berpotensi bersaing sebagai elemen struktur yang banyak digunakan untuk kehidupan sehari-hari masyarakat sejak masa lampau adalah bambu. Seperti pada bangunan Amfiteater Taman Buah Mekarsari yang berlokasi di Kota Bogor, konstruksi bambu pada atap yang juga merupakan pelingkup ruang tidak hanya memiliki fungsi struktural sebagai penyalur beban, akan tetapi memiliki fungsi arsitektural yang memengaruhi ruang, aktivitas, dan pensuasanaan ruang dengan kekhasannya sebagai material alam yang memberi kesan menarik dan indah.Tujuan penelitian ini adalah untuk mengetahui kemampuan struktural juga keindahan arsitektural yang optimal dan fungsional pada bangunan Amfiteater Taman Buah Mekarsari. Metode penelitian yang digunakan ialah metode kualitatif dengan cara memperoleh data melalui studi literatur, pengamatan langsung terhadap bangunan dan lingkungannya, melakukan dokumentasi visual, wawancara dengan arsitek bangunan, penggunaan software simulasi struktur, serta model analog.Melalui penelitian dapat disimpulkan bahwa pemilihan struktur rafter roof mampu mempertahankan bentuk bangunan Amfiteater Taman Buah Mekarsari yang simetris dan juga memberikan pensuasanaan melalui susunan strukturnya terhadap ruang dalam dan mempertahankan pesan yang terdapat pada konsep bangunan.
Expansão da educação superior a distância: a questão da institucionalização
Authors: Silva Rosineide Da , Vilela Tânia Jucilene Vieira 
Published: January 2020

O artigo em questão trata da educação superior brasileira e sua expansão na modalidade a distância. A partir da aprovação da LDB - Lei 9.394/1996, precisamente em seu artigo 80 que trata da educação a distância, muito tem sido o crescimento desta modalidade no Brasil. Dessa forma, os cursos a distância em instituições públicas são ofertados por meio de Convênio entre a Coordenadoria de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), os Estados, Municípios e as Universidades, após o credenciamento dessa junta ao Ministério da Educação (MEC). Para o embasamento teórico será utilizado estudiosos como: DOURADO (2011); MERCADO (2011); PRETI (2009), que vão trazer pontos relevantes para nosso estudo e discussões acerca da educação brasileira, a modalidade a distância e a institucionalização e, as políticas públicas no ensino superior. No entanto, essa expansão de relevância acelerada em instituições públicas e privadas, tem levado a discussão no interior das universidades, especialmente as públicas, a pensar a questão da institucionalização desse ensino. Assim, o trabalho vem trazer reflexões bibliográficas sobre o que está sendo abordado na atualidade.
Tumor Mimicking in Musculoskeletal System in Surabaya: A Case Series
Authors: Hadi Bayu Antara , Edward Mouli 
Published: January 2020

ABSTRACTMusculoskeletal tumors are potential causes of heavy morbidity and economic burdens for patients. There are often cases suspected as musculoskeletal tumors based on a specific diagnostic modality because of overlapping features upon physical examination or a tumor-like appearance from the radiological examination, the more reason for triple diagnosis to be performed for an exact diagnosis. We report 5 cases of fractures tumor-mimicking lesions. The First patient, a patient with MRI revealing a primary malignant bone tumor, but with plain thorax x-ray and FNAB, the diagnosis was tuberculosis arthritis of the elbow. The second patient shows metastatic proses with plain radiographic, but from open biopsy, the diagnoses fall to chronic osteomyelitis. The third patient had a history of papillary carcinoma thyroid with pathological fracture of proximal of the left femur, but the biopsy shows a hypercalcemic state. The fourth patient, had mass size 20x15 cm at the thigh, but the biopsy shows Non-Specific Chronic Osteomyelitis. The fifth patient with progressive swelling of the left knee for one year, 10x10 cm in size, the biopsy showed no sign of malignancy but tuberculosis of left distal femur. In conclusion, standard comprehensive diagnosis steps consisting of clinical history, imaging, laboratory and histopathological examinations are crucial to differentiate tumor-mimicking lesions from neoplasms, thus ensuring proper treatment.Keywords: Tumour mimicking, osteosarcoma, chondroma, malignancy
Fiber consumption effect on non-communicable disease: how big is the impact?
Authors: Indarti Yuli 
Published: January 2020

Abstract Non-communicable diseases have effects on the quality of human resources because, in addition to causes of death and morbidity, they also reduce productivity. Fiber intake was allegedly affecting the incidence of non-communicable diseases. The purpose of this literature review is to look at the link between fiber intake and the incidence of non-communicable diseases and the effect of fiber supplements to treat non-communicable diseases. Several literature indicate that fiber intake is associated with cardiovascular disease, diabetes mellitus, cancer, and obesity. Research also shows fiber supplementation can improve metabolic profiles, blood sugar, insulin resistance in cardiovascular and diabetes mellitus patients. Fiber supplementation also reduces the risk of breast cancer. Fiber intake is related to the incidence of non-communicable diseases and can overcome some non-communicable diseases Keywords : fiber, cardiovascular disease, diabetes mellitus, cancer, supplement
Ankle Arthrodesis with Cannulated Screw: Case Series
Authors: Desnantyo Andre Triadi , Chilmi Muhammad Zaim , Yazid Hizbillah 
Published: January 2020

ABSTRACT Ankle osteoarthritis patients are young and lack of available long last treatment. Ankle arthrodesis remains the gold standard and is the procedure of choice for younger patients who are heavy laborers. These case series evaluate and report five patients undergone ankle arthrodesis at RSUD Dr. Soetomo Surabaya on 2012-2016. The data were collected from patient files, radiographs, and a recent physical examination. The outcome has been assessed with SF-36 score and clinical scoring system Ankle-Hind foot American Foot and Ankle Society. Three male patients and two female patients underwent ankle arthrodesis with cannulated screw, caused by neglected severe ankle dislocation. One patient had open dislocation. Based on SF-36 scoring, the five patients had average score 76,7 with highest and lowest score were 95,9 and 56,7. Based on clinical score ankle-hind foot American Ankle and Foot Society, the average score was 68(51 – 88). The scoring result includes general health, physic, emotional, and social. And clinical scoring ankle-hind foot American Foot and Ankle Society evaluation includes pain, function, and alignment. It shows that there was patient that gains an almost perfect result. Patient with the lowest score also had knee osteoarthritis contralateral from the operated ankle. Early weight bearing on ankle arthrodesis with cannulated screw was the major factor caused unsatisfactory result of this patient. Ankle arthrodesis with cannulated screw has satisfactory result eventhough remain complain on one patient. Nevertheless, ankle arthrodesis with cannulated screw still has an important role in the treatment of choice on ankle reconstruction.Keywords : Ankle arthrodesis, cannulated screw, ankle joint fusion
Anatomical and Sexual Functions at Post Neovagina operation on Mayer Rokitansky Kuster Hauser Syndrome (MRKH) Patients with Sigmoid ,Amnion and Conventional Methods in Dr. Soetomo Hospital
Authors: Marlina Uning , Parathon Hari , Demas Azami , Yanuar Jimmy , Kristian Iwan 
Published: January 2020

ABSTRACT Background: The Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome is congenital malformation due to utero‐vaginal agenesis. For many years Dr Soetomo Hospital has been applying McIndoe technique using biomaterial amnion. Recently, in collaboration with digestive surgery, neovagina operation using sigmoid was performed. However, no data are available on the complications, anatomic, and functional results of the neovagina operation using sigmoid and amnion. Methods: MRKH patients who have performed neovagina operations from January 2011 to December 2014 were involved in this case review. The anatomical function was measured based on minimal vaginal length of more than 6 cm and width of 3 cm, while sexual performance is measured by Female Sexual Function Index (FSFI), which is above 23, and Female Sexual Distress Score Revised (FSDSR), whose score is < 11. Result: In 4 years period, there were 6 cases of MRKH underwent neovagina (1 used sigmoid and 5 used amnion) at Dr Soetomo Hospital. All of them had a satisfying anatomical and sexual function. Even though neovagina operation significantly reduces sexual distress, but it does not necessarily mean alleviate as seen by the high FSDSR score. Neovagina using amnion has faster operation time and cheaper with the same length of hospital stay than sigmoid neovagina. Sigmoid neovagina has a better vaginal length, lubrication and no need dilatation after operation, but it has higher complication risk. Conclusion: The Neovagina technique should be used at Soetomo Hospital depends on patient wishes and circumstances. For those who have strong financial support and are not willing to do manual dilatation, they should use the sigmoid neovagina, while those who are able to do manual dilatation, then the amnion neovagina is a good choice.Keywords: Neovagina, MRKH, sigmoid, amnion, anatomic function
Dépression et anxiété chez des patients tunisiens atteints de cancers colorectaux : spécificités et ampleur
Authors: Bouriga R. , Mahjoub M. , Chaouch MA , Hochlef M. , El Kissi Y. , Ben Ahmed S. 
Published: January 2020

Introduction : Le cancer est à l’origine de détresse psychologique alourdissant les morbidités des patients. Le cancer colorectal constitue un problème de santé publique de par son ampleur et sa gravité, en plus de son retentissement psychologique chez les patients et chez leur entourage. Notre objectif est de déterminer la prévalence de la dépression et de l’anxiété chez un groupe de patients tunisiens atteints de cancer colorectal et d’en rechercher les éventuelles relations avec les données cliniques.
Patients et méthodes : Nous avons mené une étude observationnelle longitudinale prospective durant six mois (de mars à août 2017) colligeant tous les patients présentant un cancer colorectal et suivis à la consultation d’oncologie médicale au CHU Farhat-Hached à Sousse (Tunisie). En plus d’une grille à remplir par l’enquêteur se rapportant aux données épidémiologiques et cliniques du patient après l’entretien et la consultation du dossier médical, la mesure de l’anxiété et de la dépression a été faite à l’aide d’un autoquestionnaire validé en langue arabe : l’Hospital Anxiety and Depression Scale (HADS). La saisie et l’analyse des données ont été faites par le logiciel SPSS V20.0.
Résultats : Cinquante-deux patients ont accepté de répondre à notre questionnaire. Ils étaient répartis en 28 femmes et 24 hommes ; l’âge moyen était de 57 ± 13 ans, la durée moyenne de la maladie était de 3,2 ± 1 ans. Les patients inclus dans l’étude étaient au stade métastatique (stade IV) de leur maladie dans 27%des cas. Nos patients ont bénéficié d’un traitement curatif dans 54 % des cas, d’une chirurgie de la tumeur primitive dans 88,6 %, d’une chimiothérapie dans 94,3 %, d’une radiothérapie dans 34,6 %, et 15,5 % ont reçu le cetuximab. La dépression détectée auprès de nos patients était douteuse dans 17,3 %et certaine dans 13,5 %. L’anxiété était douteuse chez 13,5 % et certaine dans 7,5 %. Une corrélation positive significative a été mise en évidence entre d’une part la symptomatologie dépressive et d’autre part le stade métastatique de la maladie (r = 0,741, p = 0,042), la présence de stomie (r = 0,811 ; p = 0,005), la fatigue (r = 0,720 ; p = 0,005) et les effets indésirables à type de nausée et vomissement (r = 0,653 ; p = 0,045).
Conclusion : Il existe une forte prévalence de la dépression et de l’anxiété chez les patients atteints de cancer colorectal dans notre travail. Ces troubles psychiques devraient être systématiquement recherchés afin de préconiser une prise en charge adéquate de ces patients dans leur parcours de soins.