bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distinct SARS-CoV-2 Antibody Reactivity Patterns in Coronavirus Convalescent Plasma Revealed by a Coronavirus Antigen Microarray
Authors: Assis Rafael , Jain Aarti , Nakajima Rie , Jasinskas Algis , Khan Saahir , Dumont Larry J. , Kelly Kathleen , Simmons Graham , Stone Mars , Di Germanio Clara , Busch Michael , Felgner Philip L. 
Published: September 2020

AbstractA coronavirus antigen microarray (COVAM) was constructed containing 11 SARS-CoV-2, 5 SARS-1, 5 MERS, and 12 seasonal coronavirus recombinant proteins. The array is designed to measure immunoglobulin isotype and subtype levels in serum or plasma samples against each of the individual antigens printed on the array. We probed the COVAM with COVID-19 convalescent plasma (CCP) collected from 99 donors who recovered from a PCR+ confirmed SARS-CoV-2 infection. The results were analyzed using two computational approaches, a generalized linear model (glm) and Random Forest (RF) prediction model, to classify individual specimens as either Reactive or Non-Reactive against the SARS-CoV-2 antigens. A training set of 88 pre-COVID-19 specimens (PreCoV) collected in August 2019 and102 positive specimens from SARS-CoV-2 PCR+ confirmed COVID-19 cases was used for these analyses. Results compared with an FDA emergency use authorized (EUA) SARS-CoV2 S1-based total Ig chemiluminescence immunoassay (Ortho Clinical Diagnostics VITROS® Anti-SARS-CoV-2 Total, CoV2T) and with a SARS-CoV-2 S1-S2 spike-based pseudovirus micro neutralization assay (SARS-CoV-2 reporter viral particle neutralization titration (RVPNT) showed high concordance between the 3 assays. Three CCP specimens that were negative by the VITROS CoV2T immunoassay were also negative by both COVAM and the RVPNT assay. Concordance between VITROS CoV2T and COVAM was 96%, VITROS CoV2T and RVPNT 93%, and RVPNT and COVAM 95%. The discordances were all weakly reactive samples near the cutoff threshold of the VITROS CoV2T immunoassay. The multiplex COVAM allows CCP to be grouped according to antibody reactivity patterns against 11 SARS-CoV-2 antigens. Unsupervised K-means analysis, via the gap statistics, as well as hierarchical clustering analysis revealed 3 main clusters with distinct reactivity intensities and patterns. These patterns were not recapitulated by adjusting the VITROS CoV2T or RVPNT assay thresholds. Plasma classified according to these reactivity patterns may be better associated with CCP treatment efficacy than antibody levels alone. The use of a SARS-CoV-2 antigen array may be useful to qualify CCP for administration as a treatment for acute COVID-19 and to interrogate vaccine immunogenicity and performance in preclinical and clinical studies to understand and recapitulate antibody responses associated with protection from infection and disease.
Locus-specific introgression in young hybrid swarms: drift dominates selection
Authors: McFarlane S. Eryn , Senn Helen V. , Smith Stephanie L. , Pemberton Josephine M. 
Published: September 2020

AbstractClosely related species that have previously inhabited geographically separated ranges are hybridizing at an increasing rate due to human disruptions. These anthropogenic hybrid zones can be used to study reproductive isolation between species at secondary contact, including examining locus-specific rates of introgression. Introgression is expected to be heterogenous across the genome, reflecting variation in selection. Those loci that introgress especially slowly are good candidates for being involved in reproductive isolation, while those loci that introgress quickly may be involved in adaptive introgression. In the context of conservation, policy makers are especially concerned about introduced alleles moving quickly into the background of a native or endemic species, as these alleles could replace the native alleles in the population, leading to extinction via hybridization. We applied genomic cline analyses to 44997 SNPs to identify loci introgressing at excessive rates when compared to the genome wide expectation in an anthropogenic hybridizing population of red deer and sika in Kintyre Scotland. We found 11.4% of SNPs had cline centers that were significantly different from the genome wide expectation, and 17.6% had excessive rates of introgression. Based on simulations, we believe that many of these markers have diverged from average due to drift, rather than because of selection. Future work could determine the policy implications of allelic-replacement due to drift rather than selection, and could use replicate, geographically distinct hybrid zones to narrow down those loci that are indeed responding to selection in anthropogenic hybrid zones.
Candidatus (Ca.)phytoplasma asteris subgroups display distinct disease progression dynamics during the carrot growing season
Authors: Clements Justin , Bradford Benjamin Z. , Garcia Marjorie , Piper Shannon , Huang Weijie , Zwolinska Agnieszka , Lamour Kurt , Hogenhout Saskia , Groves Russell L. 
Published: September 2020

AbstractAster Yellows phytoplasma (AYp;Candidatus (Ca.)Phytoplasma asteris) is an obligate bacterial pathogen that is the causative agent of multiple diseases in herbaceous plants. While this phytoplasma has been examined in depth for its disease characteristics, knowledge about the spatial and temporal dynamics of pathogen spread is lacking. The phytoplasma is found in plant’s phloem and is vectored by leafhoppers (Cicadellidae: Hemiptera), including the aster leafhopper,Macrosteles quadrilineatusForbes. The aster leafhopper is a migratory insect pest that overwinters in the southern United States, and historical data suggest these insects migrate from southern overwintering locations to northern latitudes annually, transmitting and driving phytoplasma infection rates as they migrate. A more in-depth understanding of the spatial, temporal and genetic determinants of Aster Yellows disease progress will lead to better integrated pest management strategies for Aster Yellows disease control. Carrot,Daucus carotaL., plots were established at two planting densities in central Wisconsin and monitored during the 2018 growing season for Aster Yellows disease progression. Symptomatic carrots were sampled and assayed for the presence of the Aster Yellows phytoplasma. Aster Yellows disease progression was determined to be significantly associated with calendar date, crop density, location within the field, and phytoplasma subgroup.
Audit committee returnees and auditor choice: evidence from China
Authors: Zhou Zejiang , Wang Haoran , Cheng Xiaoyan 
Published: September 2020

PurposeThe purpose of this paper is to examine whether the presence of returnees serving on the audit committee affects auditor choice in emerging markets.Design/methodology/approachUsing a logistic model, this study tests the relationship between the presence of returnees in the audit committee and auditor selection and how this relationship varies with the level of agency costs. The authors also perform several other additional analyses to ensure the robustness of the results, including propensity score matching, Heckman’s two-stage model and change analysis.FindingsUsingA-share listed companies in China from 2008 to 2016, the authors find a positive association between the presence of audit committee returnees and a demand for high-quality auditors and such association is strengthened in firms with a higher level of agency costs. The authors further find that discretionary accruals and the incidence of financial restatements are lower in firms with audit committee returnees.Research limitations/implicationsAlthough this study focuses on audit committee members with foreign study or foreign work experience, it remains to be seen if similar effects could be achieved through foreign ownership or work experience with foreign customers or suppliers.Originality/valueThis study provides evidence on a new channel of international knowledge spillover through which the emigration of talent increases board monitoring by demanding high-quality auditors in an emerging economy.
Investigating the role of theory of planned behavior and Machiavellianism in earnings management intentions
Authors: Sayal Kangan , Singh Gurparkash 
Published: September 2020

PurposeThe purpose of this study is to develop and empirically test the earnings management (EM) behavior model to investigate the personal psychological factors that influence individuals’ intentions to engage in EM.Design/methodology/approachFollowing a review of literature, personal-psychological factors influencing EM intentions were identified within the scope of the theory of planned behavior (TPB) and a dark triad of personality theory. The survey data from 153 MBA students were analyzed using partial least square-structural equation modeling.FindingsThe results revealed perceived behavior control is significant in influencing individuals’ EM intentions followed by attitude toward behavior and subjective norms. The results, however, do not support the relationship between moral obligation and intentions to engage in EM and also reported a negative relationship between Machiavellianism and individuals’ EM intentions.Practical implicationsThe proposed model will enable organizations to develop focused training programs for managers to reduce EM behavior. It will also help educators in training students to positively shape their ethical behavior and make them more reciprocal toward others and their work environment.Originality/valueThe study develops the EM behavior model and suggests that TPB and Machiavellianism personality traits provide a useful framework to identify the personal psychological factors influencing individuals’ EM intentions. Further, the empirical testing of the model documents and contributes toward a better understanding of the personal psychological factors significantly influencing individuals’ EM intentions.
Greening Chinese agriculture: can China use the EU experience?
Authors: Qiu Huanguang , van Wesenbeeck C.F.A. , van Veen W.C.M. 
Published: September 2020

PurposeChina's Government in 2015 announced its goal of stabilizing the use of fertilizers and pesticide by the year 2020. However, implementation of effective policies is not straightforward, while one may even argue that the policy goal is by far not ambitious enough. Hence, it is useful to look at experiences of other countries that have gone through a similar process. In this paper, the authors explicitly consider the case of European Union's (EU’s) policies aimed at greening agriculture. The choice for the EU is motivated by the fact that the EU is about 35 years ahead of China in implementing a policy agenda to counter the problems China is facing now.Design/methodology/approachIn this paper, the authors focus on agricultural inputs, in particular fertilizer and pesticides, as well as land use and their impact on food safety, air and water quality, soil degradation, greenhouse gas (GHG) emissions and biodiversity. Policies related to those issues are discussed for both, China and the EU. Given that implementation and monitoring are critical for the success of policies, the authors also discuss how policies are implemented and monitored under different governance and institutional conditions.FindingsFrom the EU experiences, positive and negative, three central lessons are drawn: (1) China should strive for cross compliance but in two steps. In the first step, arrangements for on-farm monitoring must be made, coupled with a pilot program of cross-compliance conditions for large farms in selected counties; in the second step, cross-compliance requirements must be introduced for all farmers, with additional funds for rural development in vulnerable areas. (2) Strong stakeholder commitment should be sought in the formulation as well as implementation of greening policies. (3) Monitoring of greening results should be harmonized and standardized across the country, with a limited number of indicators.Originality/valueThis paper contributes to the policy discussion by comparing the agricultural greening measures in the EU (which was some 35 years ago in the same situation as China now) with the measures taken in China so far.
White and minority employee reactions to perceived discrimination at work: evidence of White fragility?
Authors: Ng Eddy S. , Sears Greg J. , Bakkaloglu Muge 
Published: September 2020

PurposeBuilding on the notion of “White fragility,” this study aims to explore how Whites react and cope with perceived discrimination at work. Specifically, the authors explore whether: (1) Whites react more negatively than minorities when they perceive discrimination at work and (2) Whites are more likely than minorities to restore the status quo by leaving the situation when they perceive discrimination at work.Design/methodology/approachData for this study were obtained from the Professional Worker Career Experience Survey. In total, 527 working professionals from multiple organizations across the central USA participated in the survey.FindingsThe authors find evidence that Whites experience more negative psychological effects (i.e. lower job satisfaction and higher work stress) from perceived discrimination than minority employees and are more likely to act to restore conditions of privilege by leaving their current job and employer. The stronger negative effects of perceived discrimination for Whites (vs minorities) were restricted to work outcomes (job satisfaction, work stress, turnover intentions from one's employer) and were not evident with respect to perceptions of overall well-being (i.e. life satisfaction), suggesting that White fragility may play a particularly influential role in work settings, wherein racial stress may be more readily activated.Originality/valueConsistent with the notion of White fragility, the study’s results demonstrate that the deleterious impact of perceived discrimination on employee work outcomes may, in some cases, be stronger for White than minority employees.
Research on sealing performance of oil seals with micro-dimple texture on lips
Authors: Zhang Fuying , Zhang Yuanhao 
Published: September 2020

Purpose
The purpose of this paper is to study the pumping efficiency of oil seals with different surface textures at different speeds, and the influence of the rotation direction of triangular texture on the sealing performance was further analyzed.

Design/methodology/approach
Based on the theory of elastohydrodynamic lubrication and the pumping mechanism of rotary shaft seals, establishing a numerical model of mixed lubrication in oil seal sealing area. The model is coupled with the lip surface texture parameters and the two-dimensional average Reynolds equation considering the surface roughness.

Findings
The results show that the application of lip surface texture technology has obvious influence on the oil film thickness, friction torque and pumping rate of oil seal. The triangular texture has the most significant effect on the increase of pump suction rate. When the rotation direction of triangular texture is 315 degrees, the pumping rate of oil seal is the largest compared with the other seven directions.

Originality/value
The model has a comprehensive theoretical guidance for the design of new oil seal products, which provides a certain basis for the application of surface texture technology in the field of sealing in the future.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-06-2020-0198/
“Feeling the waste” evidence from consumers’ living in Gaza Strip camps
Authors: Raab Katharina , Wagner Ralf , Salem Mohammed 
Published: September 2020

Purpose
This paper aims to quantify the impact of antecedents (frustration, locus of control, spirituality, and religion and attention to social-comparison information) on the intensity of emotional outcomes of consumers’ disposal behaviour.

Design/methodology/approach
A structural equation model fitted with PLS was used to evaluate data obtained from 323 self-administered questionnaires filled out in a stratified random sample of respondents living in Gaza Strip camps.

Findings
Spirituality and religion, and attention to social-comparison information have the highest impacts on emotional outcomes related to consumer disposal behaviour.

Research limitations/implications
Spirituality and religion are seldom considered in previous consumer research, but they turn out to have high relevance for disposal-related emotions.

Originality/value
To the best of the authors’ knowledge, this is the first study investigating disposal-related emotions. Moreover, it is also the first study combining the impact of frustration, locus of control, perceived self-efficacy, spirituality and religion and attention to social-comparison information on emotional outcomes related to consumers’ disposal behaviour.
Mediterranean diet and oxidative stress
Authors: Górska Paulina , Górna Ilona , Przysławski Juliusz 
Published: September 2020

Purpose
This study aims to analyze the antioxidant properties of the Mediterranean diet and describe methods that are used in clinical studies to assess its role in reducing oxidative stress.

Design/methodology/approach
The review presents the results of interventional and observational clinical trials aimed at assessing the influence of the Mediterranean diet on the level of enzymatic and non-enzymatic antioxidants, as well as the total blood antioxidant capacity.

Findings
The Mediterranean diet as a varied diet can be a better way to provide antioxidants to the body than supplements. Individual compounds administered in an isolated form can give the opposite effect to the expected, stimulating oxidative stress. The administration of antioxidants in the form of supplements instead of a varied diet is also associated with a lack of synergism of action. In studies on the importance of the Mediterranean diet in the reduction of oxidative stress, single markers are used to measure oxidative damage, the activity of enzymatic antioxidants and the concentration of individual non-enzymatic antioxidants. At the same time, the need to find markers that would assess the level of oxidative stress and the body’s antioxidant capacity more comprehensively is emphasized.

Practical implications
It should be taken into account that differences between in vivo and in vitro results may result from the fact of various factors, including genetic, smoking, intestinal microflora or diet composition. It is also necessary to answer the question about which marker or set of markers could in the most comprehensive way to assess the level of oxidative stress and the body’s antioxidant capacity.

Originality/value
The literature review shows not only the source of antioxidants in the Mediterranean diet. This paper also presents a critical approach to markers that allow the assessment of the antioxidant properties of the diet.
Effects of union commitment on job performance in China
Authors: Huang Wenyuan , Yuan Chuqin , Shen Jie , Li Min 
Published: September 2020

PurposeThis study aims to reveal the mechanism through which union commitment influences job performance in China, focusing on the mediating role of employee participation and the moderating role of affective commitment.Design/methodology/approachIn this study, a cross-sectional design was employed to collect data from 596 union members in 33 unionized enterprises in China's Pearl River Delta region.FindingsThe results demonstrate that union commitment is positively related to both employee participation and job performance. Moreover, employee participation mediates the positive relationship between union commitment and job performance. In addition, affective commitment strengthens the relationship between union commitment and employee participation and the mediating effect of employee participation.Practical implicationsThis study indirectly identifies the impact of a union on organizational performance from an individual-level perspective. It also provides new evidence for union construction in order to obtain support from corporate executives in China.Originality/valueThis study makes an important contribution to the literature by proposing and examining the mediating role of employee participation and the moderating role of affective commitment in the underlying mechanism between union commitment and job performance.
University budgeting: internal versus external transparency
Authors: Conesa Carril Maria C. , Gómez Aguilar Nieves , Larrán Jorge Manuel 
Published: September 2020

PurposeThe analysis intends to clarify whether higher education institutions place as much value on internal transparency as on external transparency. This study aims to analyze the university budgeting process as a reflection of internal transparency. It also aims to identify the weaknesses of the budgeting process regarding transparency in order to improve decision-making.Design/methodology/approachA case study that applies mixed methods – documentary analysis, observations and interviews – has been conducted. To study internal transparency, the model of three levels of transparency of Biondi and Lapsley (2014) has been applied to the budgeting process of a university. Then, the results have been compared to the external transparency of this institution.FindingsWhile external transparency is achieved, internal transparency in the budgeting process is far from optimal in the case of study. An improvement in transparency of the budget process can promote the engagement of stakeholders in the process and achieve better governance.Research limitations/implicationsThe general inductive approach is not as strong as other approaches in the area of theory or model development. However, it does provide a simple approach for deriving findings linked to this research’s questions.Practical implicationsTrust issues and external accountability appear to be more relevant than internal transparency for universities. However, improving the three levels of transparency along the budgeting process could motivate collegiate members to reinforce accountability, as it requires them to effectively communicate their actions and decisions to their represented.Originality/valueThis paper seeks to situate transparency as an attribute of university governance, contributing to the scarce literature on transparency, internal and external, in the university. The study compares the approach of this university to external transparency – which relates to accountability – with internal transparency – a concept that links to corporate governance. This study uses the novel lens of Biondi and Lapsley model (2014) to study internal transparency, focussing on university budgeting as a key management tool.