bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is it possible to obtain consensus on the tactics of early rehabilitation period after lumbar microdisCectomy?
Authors: Tursynov N. I. , Grigolashvili M. A. , Sheveleva N. I. , Muratbekova Sh. S. 
Published: June 2020

Objective. To analyze distinctions in multidisciplinary approaches with respect to the timing of patients returning to daily physical activity after uncomplicated lumbar microdisectomy and to the readiness of doctors of various specialties to work according consensus guidelines.Material and Methods. A written questionnaire survey of 60 specialists (20 neurosurgeons, 28 neurologists and 12 rehabilitologists) involved in the management of patients during the first six months after uncomplicated lumbar microdisectomy was conducted. The questionnaire included 12 questions with several answer options on the timing of returning to daily physical activity, and on the need to provide patients with written recommendations on limitations in motion regimen, physical work, sexual activity, and bracing.Results. Significant dissonance both between doctors of the same specialty and of different specialties was demonstrated in the tactics of postoperative management of patients regarding the recommended terms for returning to daily activity. All respondents found it useful to create unified written recommendations on the motion regime, 90 % of specialists are ready to use the proposed recommendations after some modification. There was a slight increase in the recommended timing for return to daily physical activity compared with the recommendations of doctors in other countries.Conclusion. The demonstrated interdisciplinary differences in the treatment, rehabilitation and timing of physical activity restriction for patients after lumbar microdisectomy require unification of the tactics of postoperative management.
Arteriomesenteric compression of the duodenum as a complication of the surgical correction of typical idiopathic scoliosis: clinical case
Authors: Ryabykh S. O. , Scryabin E. G. , Chevzhik V. P. , Filatov E. Yu. 
Published: June 2020

The presented rare clinical case of the development of arteriomesenteric compression of the duodenum is described with the aim of informing a wide audience of specialists (orthopedic trauma surgeons, vertebrologists, neurosurgeons, surgeons, neurologists and pediatricians) about a rare complication of surgical correction of typical adolescent idiopathic scoliosis intestinal obstruction due to compression of the lower horizontal part of the duodenum by the superior mesenteric artery. Publications answering two posed questions were analyzed: is there a correlation between surgical correction of scoliosis and development of abdominal pathology in a patient in the immediate postoperative period, and should the instrumentation be completely or partially removed at the level of the thoracolumbar junction in the case of formation of duodenal arteriomesenteric compression in a patient operated on the spine? Abdominal visceral complications are extremely rare and represented by a very few publications even in modern electronic databases of medical information, therefore we consider it important to bring a case from our practice to the attention of readers.
Transpedicular fixation for hematogenous pyogenic vertebral osteomyelitis
Authors: Bazarov A. Yu. 
Published: June 2020

Objective. To analyze the effectiveness of conservative treatment and extrafocal transpedicular fixation in patients with uncomplicated hematogenous pyogenic vertebral osteomyelitis (PVO).Material and Methods. Ninetyseven medical records of in-patients who were treated for hematogenous PVO in 2007–2017 were analyzed. Among them, men accounted for 73.2 % (n = 71) and women – 26.8 % (n = 26). The acute and subacute forms of the disease were diagnosed in 62 (63.9 %) patients and chronic – in 35 (36.1 %). Type A according to Pola classification totaled 45 patients, type B – 49 and type C – 3. Sixtyfour (66.0 %) patients were treated conservatively, 33 (34.0 %) – using transpedicular fixation and 25 (75.8 %) – using minimally invasive technique. No fixators were placed in the affected vertebrae. All patients underwent antibacterial therapy lasting 6–12 weeks.Results. Good treatment results were obtained in 89 (91.8 %) patients. There were no differences in the severity of pain between the comparison groups before the start of treatment and after one year. However, the pain severity was significantly reduced (p = 0.001) over the time of treatment. Positive results of transpedicular fixation were obtained in 28 (84.8 %) cases, and after three repeated interventions – in 32 (94.1 %), and those of conservative treatment – in 61 (95.3 %) cases. The total number of relapses was 8 (8.2 %), of complications – 3 (3.1 %). The risk of relapse among operated drug addicts was significantly higher (p = 0.033). There were no deaths in the comparison groups, which is explained by the study inclusion and exclusion criteria. All discharged patients were followed-up on an outpatient basis for at least a year, and 72.2 % of them – from 1 year to 8 years.Conclusion. Transpedicular fixation is indicated for uncomplicated hematogenous pyogenic vertebral osteomyelitis, monosegmental lesions and in cases of demands on improved quality of life. The use of such a technique in drug addicts is not recommended.
Fertilizer application enhances establishment of cacao seedlings in plant-parasitic nematodes infected soil
Authors: ORISAJO Samuel Bukola , ADEJOBI Kayode Babatunde 
Published: June 2020

Low soil fertility, pests and diseases are major problems of growth and establishment of cacao seedlings on the field. Cocoa production increases by new plantings and rehabilitation of moribund farms, but a build-up of plant-parasitic nematodes (PPN) causing dieback and declining soil fertility has discouraged many farmers, leading to a reduction in crop productivity. In this study, the potentials of some organic wastes as fertilizers and their effects on establishment of cacao seedlings in PPN infected soils was investigated at Ibadan and Owena of Southwestern Nigeria. Goat dung (GD), organic fertilizer (OF), organo-mineral fertilizers (OMF) and NPK 15:15:15 were applied at 200, 400 and 600 kg ha-1, respectively, to cacao seedlings one month after transplanting, while unfertilized served as control. Results from the experiments showed a significant increase in percentage survival of cacao seedlings under organic fertilizers at Ibadan and Owena compared to NPK and control even at the lowest rate of 200 kg ha-1 3 years after transplanting. The incorporation of GD, OF and OMF significantly reduced the population densities of PPN compared to control. Therefore, GD, OF and OMF at 200 kg ha-1 are recommended for soil application to enhance the field establishment of cacao seedlings in the soil infected with PPN.
Potential of controlling selected weeds in Europe with insects
Authors: ADAMIČ Sergeja , TRDAN Stanislav 
Published: June 2020

Weed control by insects is increasingly important, as chemical weed control (the use of herbicides) has an important impact on the environment and, consequently, on all organisms living there. The use of insects to control weeds thus represents an alternative to herbicides. The article presents the suppression of some widespread and persistent weeds in Europe with their natural enemies - insects. The following combinations presented below are: broad-leaved dock (Rumex obtusifolius L.) – Gastrophysa viridula (De Geer, 1775), curly dock (Rumex crispus L.) – Apion violaceum (Kirby, 1808), common ragweed (Ambrosia artemisiifolia L.) – Ophraella communa (LeSage, 1986) and Zygogramma suturalis (Fabricius, 1775), creeping thistle (Cirsium arvense (L.) Scop.) – Cassida rubiginosa (Müller, 1776), cleavers (Galium aparine L.) – Halidamia affinis (Fallen, 1807) and Sermylassa halensis (Linnaeus, 1767), common knotgrass (Polygonum aviculare L.) and black-bindweed (Fallopia convolvulus L.) – Gastrophysa polygoni (Linnaeus, 1758) and as the last one field bindweed (Convolvulus arvensis L.) – Galeruca rufa (Germar, 1824) and Tyta luctuosa (Denis in Schiffmuller, 1775).
Ari’s Burger: Vignettes of Iquitos (Part 3)
Authors: Weiskopf Jimmy 
Published: June 2020

This is the final episode of a three-part story about a visit to Iquitos at the time of the new millennium by the narrator, who lives in Colombia and has been drinking yajé (ayahuasca) with its indigenous shamans. For a book he is writing about the subject, decides to investigate its uses in Iquitos, where his host and guide to the rituals there is “Zappa”, an American expatriate who exports shamanic plants and runs ayahuasca ceremonies. Zappa is now trying to exploit a traditional plant remedy for diabetes and is unwittingly caught up in an international intrigue to do with the U.S. war against drugs. This episode starts when, after several disappointing ceremonies with unqualified or ill-intentioned healers, the narrator drinks ayahuasca with a skilled and ethical shaman.
Diagnóstico Serológico de Neospora caninum en vacas del municipio de Tuta, Boyacá
Authors: Cruz-Estupiñan S. , Diaz-Anaya A. , Bulla-Castañeda D. , Garcia-Corredor D. , Pulido-Medellín M. 
Published: June 2020

N. caninum es un parásito protozoario del filo Apicomplexa , y ha sido reconocido como una causa importante de aborto y falla reproductiva en el ganado de todo el mundo. Aunque en Colombia existen algunos estudios sobre la seroprevalencia de esta enfermedad, la información sigue siendo limitada. Objetivo. Establecer la seroprevalencia de N. caninum en vacas lecheras del municipio de Tuta (Boyacá, Colombia). Materiales y Métodos. Se muestrearon 375 animales. Las muestras se procesaron bajo la técnica de ELISA indirecta, se realizó un análisis estadístico con la prueba de Chi-cuadrada de asociación-independencia para determinar si existía relación entre la presencia de anticuerpos contra N. caninum y las diferentes variables reproductivas. Resultados. Se observó que el 52% de los individuos fueron positivos a anticuerpos contra N. caninum, la única variable reproductiva que presentó relación estadística con la presencia del protozoo fue repetición de celo, no existió relación entre edad y raza de los bovinos y la presentación de N. caninum. Conclusión. La seroprevalencia es elevada si se tienen en cuenta los datos de seroprevalencia reportados con anterioridad en otras regiones del país, no obstante, estos resultados no demostraron la presencia de enfermedad en los animales analizados, pero si la evidencia antigénica, lo que sugiere que en algún momento de la vida se infectaron con el agente y promovieron la formación de anticuerpos específicos.
Influence of the deformation rate on phase stability and mechanical properties of a Ti–29Nb–13Ta–4.6Zr–xO alloy analyzed byin situhigh-energy X-ray diffraction during compression tests
Authors: da Silva Murillo R. , Gargarella Piter , Plaine Athos H. , Contieri Rodrigo J. , Pauly Simon , Kühn Uta , Bolfarini Claudemiro 
Published: June 2020

Abstract
The Assessment Of Sediment Contamination Level In The Lampung Bay, Indonesia: Heavy Metal Perspective
Authors: Budiyanto Fitri , - Lestari 
Published: June 2020

The potency and utilization of Lampung Bay has been recognized for their socio-economical and ecological values. However, heavy use of this Bay may alter the abundance of hazardous chemical like heavy metals. The aims of this study were to determine the concentration of Cd, Cu, Pb and Zn in the sediment and to assess Lampung Bay water condition. The observation of heavy metal content in sediment of Lampung Bay was conducted at 13 stations in March 2008. Analysis of heavy metals in sediment was conducted using three kinds of acid: HNO3, HCl and H2O2 while measurement was carried out by Atomic Absorption Spectrophotometer. The result indicated a variation of heavy metal concentration in sediment and that concentrations of Cd, Cu, Pb and Zn in sediment were 0.08 mg/kg dry weight, 22.99 mg/kg dry weight, 24.75 mg/kg dry weight and 118.48 mg/kg dry weight, respectively. Factors influenced heavy metal concentration in sediment in this study including the distance between sampling location and anthropogenic activities and the sediment fraction SQG-Q index indicated that 7 stations have SQG-Q ≤ 0.1 whereas other 6 stations have 0.1≤ SQG-Q <1, meaning that more than half sampling stations are in uncontaminated state.
THE SOAKING EFFECT OF 100% SMALL WHITE GINGER EXTRACT ON THE VALUE OF THE FLEXURAL STRENGTH OF ACRYLIC BASE (Flexural Strength Value of Acrylic Base Using Acrylic Resin Heat Cured Type)
Authors: Islami Nadya , Saputera Debby , Arifin Rahmad 
Published: June 2020

Background: The denture base material that is widely used is heat cured acrylic resin. One of mechanical properties of acrylic resin that must be considered in the selection of the basic denture material is flexural strength. Flexural strength is needed, among others, to resist the chewing power that must be received by dentures. The commonly used denture cleanser is Alkaline peroxide. 100% small white ginger extract can be used as natural denture cleanser. Objective: This study aimed to compare the flexural strength of heat cured acrylic base which in soaked 100% small white ginger extract with Alkaline peroxide solution as artificial denture cleanser. Method: This study was a pure laboratory experimental study with post test only with control group design, using simple random sampling. The sample was rectangular with a size of 65x10x2,5 mm. The number of samples used was 24 heat cured resin acrylic which was divided into 3 immersion groups, 100% small ginger extract, Alkaline peroxide, and aquades. The immersion carried out for 3 days 19 hours 25 minutes, obtained from 5 minutes denture cleanser presentation every day for 3 years. Flexural strength was tested using a Universal Testing Machine 3 Point Bending. Result: The everage flexural strength value of heat cured acrylic resin after soaked in 100% small white ginger extract was 70,98, in Alkaline peroxide 87,37, and 91,05 in aquades. The data was annalyzed using parametric One Way ANOVA test and Post Hoc Bonferroni test. Conclusion: The flexural strength of heat cured acrylic resin that soaked in 100% small white ginger extract is smaller than Alkaline peroxide after immersed for 3 days 19 hours 25 minutes.
Estimation of Mud Losses during the Removal of Drill Cuttings in Oil Drilling
Authors: Jinasena Asanthi , Sharma Roshan 
Published: June 2020

Summary
Quantification of fluid losses at the topside is beneficial for early kick-loss detection and automation of the drilling operation. A model-based estimator is a useful tool for this purpose. The real-time estimation of the amount of fluid losses with the cuttings removal could significantly help in this regard, especially for kick detection and automation. However, to the authors’ knowledge, there is no published literature on such attempts. Therefore, a simple dynamic mathematical model of the complete closed-loop oil-well drilling system is developed in this study for estimation of the fluid losses during the removal of drill cuttings at the topside, as well as for monitoring the flow of return fluid during drilling. Furthermore, this model could provide information about the topside fluid-flow rates and fluid losses to other monitoring systems, such as kick- and loss-detection systems and automation systems. The model is used to estimate both the mud-pit level and the fluid losses during the removal of the drill cuttings through the solids-removal equipment. The model-order reduction of the flowline model using orthogonal collocation allows the model to be used in real-time estimations and/or with control systems. It is simple, easy to implement, and, more importantly, shows the necessary dynamic behavior of both the bottomside and topside of a drilling operation simultaneously. The topside model can be used together with bottomside models of varying complexity to estimate both the bottomhole pressure and the fluid losses through the solids-removal system.
Build a Bioinformatics Analysis Platform and Apply it to Routine Analysis of Microbial Genomics and Comparative Genomics
Authors: Liu Hualin , Xin Bingyue , Zheng Jinshui , Zhong Hao , Yu Yun , Peng Donghai , Sun Ming 
Published: June 2020

Abstract
Genomics and comparative genomics have been increasingly used as routine methods for general microbiological researches. However, it is usually necessary to call several tools or even write some scripts to complete some simple analysis, which is complicated for most biological researchers. To simplify the operation process, especially for the convenience of microbiologists in the analysis, here we have developed PGCGAP, a comprehensive, malleable and easily-installed prokaryotic genomics and comparative genomics analysis pipeline, which implements genome assembly, gene prediction and annotation, average nucleotide identity (ANI) calculation, phylogenetic analysis, COG annotation, pan-genome analysis, inference of orthologous gene groups, variants calling and annotation and screening for antimicrobial and virulence genes. Although we have tried our best to simplify the installation and usage of PGCGAP, it may be difficult for non-bioinformatician users to master it. So, a protocol was created to help microbiologists without any experience in bioinformatics to establish their own bioinformatics platform and perform routine analysis. This protocol shows how to choose equipment, to install a Linux subsystem on a laptop with windows 10 system, to install PGCGAP and perform all analysis with an example dataset. The protocol requires a basic understanding of Linux, so an additional web page was written to help uninitiated users learn Linux and whole-genome sequencing (https://github.com/liaochenlanruo/pgcgap/wiki/Learning-bioinformatics).
Predictive factors of bowel resection due to an incarcerated groin hernia
Authors: Udaka Tetsunobu , Taniguchi Atsuki , Kozai Jun , Ootsuka Tomoaki , Watanabe Nobuyuki , Endou Izuru , Yoshida Osamu , Asano Hiroaki , Kubo Masatoshi 
Published: June 2020

Abstract
Purpose

In this retrospective study, we assessed factors that can be used to predict the need for bowel resection due to an incarcerated groin hernia.
Methods

We enrolled a total of 83 patients diagnosed with an incarcerated groin hernia on preoperative unenhanced computed tomography (CT) between January 2010 and December 2019 in our hospital. They were divided into two groups: those who underwent bowel resection and those who did not. The clinical findings, blood test results, and unenhanced CT values of patients were examined and compared between the two groups. The indication of intestinal resection was macroscopic necrosis or perforation of the incarcerated intestine.
Results

A total of 83 patients with incarcerated groin hernias were included in our study, of whom 13 (15.7%) had undergone bowel resection surgery. A univariate analysis identified a prolonged time from the symptom onset to surgery, increased white blood cell (WBC) count, increased C-reactive protein (CRP) level, decreased albumin level, and CT attenuation of the incarcerated intestinal wall at the fundus as significant predictive factors. The cut-off value for prediction of intestinal resection was 25 HU for the average CT attenuation of the incarcerated intestinal wall at the fundus and a WBC of 11,550 based on the receiver operating characteristic (ROC) curve. A multivariate analysis showed CT attenuation of the incarcerated intestinal wall at the fundus and an increased WBC count to be independent predictive factors.
Conclusions

Measuring unenhanced CT attenuation of the incarcerated intestinal wall at the fundus and the WBC count was suggested to be necessary for determining whether or not resection of the incarcerated intestine is required in cases of groin hernia.
Differential Management Strategies and Outcomes in Patients over 65 years with Acute Calculous Biliary Disease—Results and Insights from the ESTES Complicated Biliary Calculous Disease Snapshot Audit
Authors: Bass Gary Alan , Gillis Amy E. , Cao Yang , Mohseni Shahin , Group ESTES Cohort Studies Collaborative 
Published: June 2020

Abstract
Background: Acute complicated calculous biliary disease (ACCBD) may pose challenges in an ageing population. Frailty and comorbidities increase the potential risks of surgery; thus, surgeons may opt to offer operative treatments less often to their older patients. We set out to capture the incidence and treatment algorithms used across Europe to treat older patients presenting with ACCBD.Methods: Analysis of the European Society of Trauma and Emergency Surgery (ESTES) 2018 Acute Complicated Calculous Biliary Disease audit was performed. Patients undergoing emergency hospital admission with ACCBD between 1 October 2018 and 31 October 2018 were included. The primary outcome measure was operative intervention in patients over and under 65 years of age. Mortalities, post-operative morbidity, time to operative intervention, post-acute disposition and length of hospital stay were measured as secondary outcomes.Results: The median age of the 338 patients admitted to the snapshot was 67 years; 185 patients (54.7%) were over 65 years at time of admission. Significantly fewer patients over 65 underwent definitive surgical treatment, compared with those under 65 (37.8% vs. 64.7%, p <0.001). Surgical complications were seen more frequently in the over 65 cohort. Post-operative mortality was seen in 2.2% of over 65s versus 0.7% under 65(p=0.253). Mean post-operative length of stay was significantly longer in the elderly cohort. In patients surviving to discharge, post-acute convalescence or rehabilitation was required in 13.3% in the elderly cohort versus 1.9% of those under 65 (p=0.002).Conclusions: Elderly patients commonly present with ACCBD. Increased frailty and incidence of comorbid disease in this population increases the potential surgical risk. In our snapshot, elderly patients represented the majority, but far fewer were offered definitive surgical treatment. Post-operative mortality, morbidity, length of post-operative in-hospital stay and the requirement for post-discharge convalescence were higher in this group.
Identification of critical genes and pathways involved in intervertebral disc degeneration (IDD) An integrated bioinformatics analysis
Authors: Zhou Jingyang , Xin Feng , Xiao Chuyu , Zhou Wuyuan 
Published: June 2020

Abstract
Background: In western countries and China, back and neck pain has become a common problem that bothers daily life and severely influences the quality of our daily life. Among all factors that lead to chronic neck and back pain, IDD is the one that couldn’t be easily neglected. Methods: This study aims to figure out the critical genes and pathways involved in the development of IDD and provide a new aspect of following investigations on the etiology of IDD. We firstly systemically searched the GEO database and identified the differentially expressed genes (DEGs) from the expression profile dataset we selected. We secondly constructed the protein-protein interaction (PPI) network for DEGs, identified the top ten hub genes from the whole PPI network and found two statically and medically significant modules from the network, we then performed the GO and KEGG analysis on the DEGs, top ten hub genes, the PPI network and the two statically and medically modules. In the end, we provided the primers of the mRNAs of all DEGs, which will be useful for the validation experiment of this study. Results: FN1, MMP2, POSTN, COL3A1, TIMP3, FBN1, GJA1, TGFBI, EFEMP1 and ID1 were top ten hub genes identified from this study, and they may play a vital role in the development of IDD. Angiogenesis and integrin binging are crucial biological process and molecular function defined in this study, which are worthy of being intensely investigated.Conclusion: More studies on the top ten hub genes, the role of angiogenesis and integrin binding in IDD are urgently needed, which will benefit the prevention, screening, diagnosis and prognosis of IDD.