bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cyberchondriasis
Authors: Pollklas Melanie , Widemann Lavinia , Lochschmidt Mirjam , Plakhuta Anna , Gerlach Alexander L. 
Published: May 2020

Abstract. Studies show a rising trend that individuals who worry about their health regularly search the internet. Recently, potentially negative effects of doing so have been highlighted. Illness anxiety and negative affectivity may influence these effects. We tested if searching the internet about a personal symptom leads to increased health concerns and if these traits have an impact. Data from 79 students were collected. Participants were asked to name and evaluate a symptom of personal concern and to research that symptom using the Internet for 5 min. Searching the internet resulted in a significant increase in health concerns and this was significantly moderated by negative affectivity but not by illness anxiety. A replication of these findings, possibly with an older sample scoring higher on illness anxiety will help to better understand the relations described above, and to point consumers and health professionals into the right direction regarding media usage.
Efficacy of a Psychological Single-Session Intervention in	Non-Cardiac Chest Pain
Authors: Schroeder Stefanie , Achenbach Stephan , Martin Alexandra 
Published: May 2020

Abstract. Despite medical reassurance, non-cardiac chest pain (NCCP) frequently persists. Psychological interventions seem promising, but single-session interventions (SSI) are under-studied. To analyze the efficacy of a SSI focusing on chest pain perceptions in a randomized controlled trial (RCT), and to identify predictors of pain persistence. Individuals presenting with NCCP to a cardiology unit were randomly assigned to SSI ( N = 54) or treatment as usual ( N = 59). Follow-up assessments were 1 month (FU1) and 6 months (FU2) later. Primary outcome measures were chest pain (German Pain Questionnaire) and chest pain perceptions (IPQ-B, Reassurance Scale). Two by Three ANOVAs revealed significant improvements over time, but against expectation no significant interaction with group. Health concern and cardiac attribution following cardiac testing predicted FU2 chest pain ( p’s ≤ .018). These predictors could serve as markers to identify individuals with a risk for persisting complaints, a group that may benefit from interventions addressing dysfunctional illness perceptions.
Changes in Deep‐Sea Oxygenation in the Northeast Pacific Ocean During 32–10 ka
Authors: Saravanan Ponnusamy , Gupta Anil K. , Zheng Hongbo , Rai Santosh K. , Panigrahi Mruganka K. 
Published: May 2020

AbstractClimatic variations in the northeastern (NE) Pacific Ocean have been related to the strength of intermediate water‐driven productivity and global ocean circulation. Productivity variations and ocean circulation during the late Quaternary may have caused changes in the intensity of the oxygen minimum zone (OMZ). To understand these changes in productivity and resultant OMZ fluctuations, we analyzed benthic foraminiferal assemblages from the Cascadia margin which reveal major faunal and ecological shifts associated with the millennial‐scale climate changes during ~32–10 ka. The intermediate waters were highly variable during ~20–14 ka with increased productivity and nutrient supply to the subsurface during circa 15.5–14.5 ka. Our results suggest that suboxic environmental conditions occurred during the warm interstadials, and the Bølling‐Ållerød event was favorable for the dysoxic species. Our results further indicate that paleoclimate variations in the northeast Pacific region were mainly driven by the Pacific Intermediate Water Current.
Sequential Observations of Flux Transfer Events, Poleward‐Moving Auroral Forms, and Polar Cap Patches
Authors: Hwang K.‐J. , Nishimura Y. , Coster A. J. , Gillies R. G. , Fear R. C. , Fuselier S. A. , Petrinec S. M. , Burch J. L. , Dokgo K. , Sibeck D. G. , Giles B. L. , Russell C. T. , Strangeway R. J. , Gershman D. J. , Pollock C. J. , Khotyaintsev Y. , Torbert R. B. , Ergun R. E. , Moen J. I. , Clausen L. B. 
Published: May 2020

AbstractWe report the observation of solar wind‐magnetosphere‐ionosphere interactions using a series of flux transfer events (FTEs) observed by Magnetospheric MultiScale (MMS) mission located near the dayside magnetopause on 18 December 2017. The FTEs were observed to propagate duskward and either southward or slightly northward, as predicted under duskward and southward interplanetary magnetic field (IMF). The Cooling model also predicted a significant dawnward propagation of northward‐moving FTEs. Near the MMS footprint, a series of poleward‐moving auroral forms (PMAFs) occurred almost simultaneously with those FTEs. They propagated poleward and westward, consistent with the modeled FTE propagation. The intervals between FTEs, relatively consistent with those between PMAFs, strongly suggest a one‐to‐one correspondence between the dayside transients and ionospheric responses. The FTEs embedded in continuous reconnection observed by MMS and corresponding PMAFs individually occurred during persistent auroral activity recorded by an all‐sky imager strongly indicate that those FTEs/PMAFs resulted from the temporal modulation of the reconnection rate during continuous reconnection. With the decay of the PMAFs associated with the FTEs, patch‐like plasma density enhancements were detected to form and propagate poleward and then dawnward. Propagation to the dawn was also suggested by the Super Dual Auroral Radar Network (SuperDARN) convection and Global Positioning System (GPS) total electron content data. We relate the temporal variation of the driving solar‐wind and magnetospheric mechanism to that of the high‐latitude and polar ionospheric responses and estimate the response time.
Crustal Deformations of the Central North China Craton Constrained by Radial Anisotropy
Authors: Ai Sanxi , Zheng Yong , Wang Sixue 
Published: May 2020

AbstractSituated in a transition zone between the western and eastern North China Craton (NCC), the central NCC exhibits complex dynamics features. Significant lithosphere thinning is observed beneath the eastern NCC and the northern segment of the central NCC. To study how the crust responses to the distinct lateral variations of the lithospheric mantle, we develop a method for joint inversion of Rayleigh and Love dispersion curves based on a transverse‐isotropic (or radial anisotropy) medium and obtain a 3‐D crustal radial anisotropy model. The results reveal significant heterogeneities along the Cenozoic Fenhe‐Weihe Rift (FWR). In the northern FWR, the discretely distributed lower crust positive anisotropy and upper crust negative anisotropy suggest the rifting is mainly dominated by the active mantle upwelling resulting in the Datong volcanoes. Similarly, the northern segment of the Taihang Mountain is also strongly affected by the magmatic activities and exhibits different anisotropy properties compared to its central‐to‐southern counterpart. Based on the negative anisotropy observed in the middle‐to‐lower crust beneath most parts of the Taihang Mountain, we speculate that a lower‐crust compression model can be applied to the Taihang Mountain, which is totally different to that of the adjacent Bohai Bay Basin. Possibly, the root of the Taihang Mountain is pushed by the westward moving lower crust coupled with the lateral escaping mantle flow beneath the Bohai Bay Basin. The Taihang Mountain and the Bohai Bay Basin are formed in similar tectonic environments, but are deformed in different ways.
Prolonged Partial Melting of Garnet Amphibolite from the Eastern Himalayan Syntaxis: Implications for the Tectonic Evolution of Large Hot Orogens
Authors: Kang Dongyan , Zhang Zeming , Palin Richard M. , Tian Zoulin , Dong Xin 
Published: May 2020

AbstractThe Himalayan orogen, which formed due to collision of the Indian and Asian continents during the Early Tertiary, is a prime example of a large, hot collisional orogen. Despite decades of study, the duration of partial melting of migmatitic rocks exposed in the Himalayan orogenic core remains highly controversial. As such, we have performed detailed petrological and geochronological analyses of garnet amphibolite from the eastern Himalayan syntaxis in order to reveal the thermal conditions, tectonometamorphic mechanisms, and timing and duration of anatexis in metabasic rocks that form a major component of the thickened lower crust of the eastern Himalayan orogen. Phase equilibrium modeling and geothermobarometry show that the studied sample underwent high‐pressure granulite‐facies metamorphism and partial melting at 15−17 kbar and 805−840°C. Dehydration melting of amphibole during prograde metamorphism generated up to 20 vol. % partial melt with a granitic composition, which thus represents a potential source for Himalayan syn‐ to post‐orogenic crustal‐derived granites. Zircon U‐Pb geochronology shows that the garnet amphibolite witnessed a long‐lived anatectic and melt crystallization process lasting more than 30 Myr. Prolonged anatexis from ca. 40 to ca. 20 Ma predates initiation of the extrusion of Himalayan metamorphic core by up to 15 Myr, indicating that the thick and weak crust of the Himalayan‐Tibetan orogen must have remained stationary for this length of time, despite the ongoing continental collision. This study thus provides new insight into the tectonic evolution of hot orogens.
Hysteresis Behavior of Surface Water Fluxes in a Hydrologic Transition of an Ephemeral Lake
Authors: Cui Yifan , Liu Yuanbo , Gan Guojing , Wang Ruonan 
Published: May 2020

AbstractSurface heat fluxes are crucial to the energy and water exchanges between surface and the atmosphere. Hysteresis effect poses a challenge in model simulation of evaporation (latent heat flux, LE) at hourly or intradaily scales. The hidden mechanisms behind the hysteresis remain unclear, given the diverse reports in various climates, geographical locations, and underlying surfaces. This study took advantage of eddy covariance flux observation over Poyang Lake of China, an ephemeral lake experiencing seasonal shifts from land to water. It depicted the hysteresis behavior of LE to environmental forces for the period from May to July in 2018, a hydrologic transition period from land to water surface. Our results showed obvious clockwise hysteresis loops between LE and water vapor pressure deficit (VPD), surface temperature (Ts), and air temperature (Ta). Counterclockwise loops exhibited between LE and surface net radiation (Rn), wind speed (WS), and temperature difference (Ts‐Ta). Rn, WS, and Ts‐Ta dominants control the hysteresis effects and regulate LE variations. The hysteresis loops changed in direction, shape, and area when the surface shifted from land to water. It was primarily related to the lengthened lag time between LE and other variables except for WS, which was attributable to enhanced impacts from WS and VPD, and weakened impacts from Rn and Ts‐Ta. The findings should help to improve our understanding of the complicated water‐atmosphere interactions at the intradaily scale.
Sea Surface Salinity as a Proxy for Arctic Ocean Freshwater Changes
Authors: Fournier Séverine , Lee Tong , Wang Xiaochun , Armitage Thomas W. K. , Wang Ou , Fukumori Ichiro , Kwok Ron 
Published: May 2020

AbstractThe changing Arctic freshwater content and distribution have a significant implications for ocean circulation, climate, and water and biogeochemical cycles. The paucity of in situ salinity measurements in the Arctic Ocean has limited our ability to study Arctic‐Ocean freshwater variability. Although satellite‐derived sea surface height (SSH) and ocean bottom pressure (OBP) have been used together to infer depth‐integrated freshwater content changes, these measurements are limited in sampling and resolution. Motivated by the recent development of sea surface salinity (SSS) remote sensing, we explore the use of SSS as a proxy for Arctic freshwater changes. As a first step, here we conduct a proof‐of‐concept study by analyzing the output of an ocean‐ice state estimation product. We find that SSS variations are coherent with those of SSH‐minus‐OBP across the Arctic basin (with R ~ −0.8) except for those in the center of the Beaufort Gyre and the region affected by the subpolar North Atlantic inflow. On Arctic shelves, the linear regression coefficient between SSS and SSH‐minus‐OBP is −0.3 pss/cm or larger in magnitude. The results suggest that SSS is a good proxy for Arctic freshwater changes, and satellite SSH‐minus‐OBP can be used to evaluate satellite SSS quality.
A Middle Crustal Channel of Radial Anisotropy Beneath the Northeastern Basin and Range
Authors: Wilgus Justin , Jiang Chengxin , Schmandt Brandon 
Published: May 2020

AbstractA challenge in interpreting the origins of seismic anisotropy in deformed continental crust is that composition and rheology vary with depth. We investigated anisotropy in the northeastern Basin and Range where prior studies found prevalent depth‐averaged positive radial anisotropy (VSH > VSV). This study focuses on depth‐dependence of anisotropy and potentially distinct structures beneath three metamorphic core complexes (MCCs). Rayleigh and Love wave dispersion were measured using ambient noise interferometry, and Bayesian Markov chain Monte Carlo inversions for VSstructure were tested with several (an)isotropic parameterizations. Acceptable data fits with minimal introduction of anisotropy are achieved by models with anisotropy concentrated in the middle crust. The peak magnitude of anisotropy from the mean of the posterior distributions ranges from 3.5–5% and is concentrated at 8–20 km depth. Synthetic tests with one uniform layer of anisotropy best reproduce the regional mean results with 9% anisotropy at 6–22 km depth. Both magnitudes are plausible based on exhumed middle crustal rocks. The three MCCs exhibit ~5% higher isotropic upper crustal VS, likely due to their anomalous levels of exhumation, but no distinctive (an)isotropic structures at deeper depths. Regionally pervasive middle crustal positive radial anisotropy is interpreted as a result of subhorizontal foliation of mica‐bearing rocks deformed near the top of the ductile deformation regime. Decreasing mica content with depth and more broadly distributed deformation at lower stress levels may explain diminished lower crustal anisotropy. Absence of distinctive deep crustal VSbeneath the MCCs suggests overprinting by ductile deformation since the middle Miocene.
Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome
Authors: Laurent Anouchka P. , Kotecha Rishi S. , Malinge Sébastien 
Published: May 2020

AbstractStructural and numerical alterations of chromosome 21 are extremely common in hematological malignancies. While the functional impact of chimeric transcripts from fused chromosome 21 genes such as TEL-AML1, AML1-ETO, or FUS-ERG have been extensively studied, the role of gain of chromosome 21 remains largely unknown. Gain of chromosome 21 is a frequently occurring aberration in several types of acute leukemia and can be found in up to 35% of cases. Children with Down syndrome (DS), who harbor constitutive trisomy 21, highlight the link between gain of chromosome 21 and leukemogenesis, with an increased risk of developing acute leukemia compared with other children. Clinical outcomes for DS-associated leukemia have improved over the years through the development of uniform treatment protocols facilitated by international cooperative groups. The genetic landscape has also recently been characterized, providing an insight into the molecular pathogenesis underlying DS-associated leukemia. These studies emphasize the key role of trisomy 21 in priming a developmental stage and cellular context susceptible to transformation, and have unveiled its cooperative function with additional genetic events that occur during leukemia progression. Here, using DS-leukemia as a paradigm, we aim to integrate our current understanding of the role of trisomy 21, of critical dosage-sensitive chromosome 21 genes, and of associated mechanisms underlying the development of hematological malignancies. This review will pave the way for future investigations on the broad impact of gain of chromosome 21 in hematological cancer, with a view to discovering new vulnerabilities and develop novel targeted therapies to improve long term outcomes for DS and non-DS patients.
Remote sensing reveals Antarctic green snow algae as important terrestrial carbon sink
Authors: Gray Andrew , Krolikowski Monika , Fretwell Peter , Convey Peter , Peck Lloyd S. , Mendelova Monika , Smith Alison G. , Davey Matthew P. 
Published: May 2020

AbstractWe present the first estimate of green snow algae community biomass and distribution along the Antarctic Peninsula. Sentinel 2 imagery supported by two field campaigns revealed 1679 snow algae blooms, seasonally covering 1.95 × 106 m2 and equating to 1.3 × 103 tonnes total dry biomass. Ecosystem range is limited to areas with average positive summer temperatures, and distribution strongly influenced by marine nutrient inputs, with 60% of blooms less than 5 km from a penguin colony. A warming Antarctica may lose a majority of the 62% of blooms occupying small, low-lying islands with no high ground for range expansion. However, bloom area and elevation were observed to increase at lower latitudes, suggesting that parallel expansion of bloom area on larger landmasses, close to bird or seal colonies, is likely. This increase is predicted to outweigh biomass lost from small islands, resulting in a net increase in snow algae extent and biomass as the Peninsula warms.
Red-phosphorus-impregnated carbon nanofibers for sodium-ion batteries and liquefaction of red phosphorus
Authors: Liu Yihang , Liu Qingzhou , Jian Cheng , Cui Dingzhou , Chen Mingrui , Li Zhen , Li Teng , Nilges Tom , He Kai , Jia Zheng , Zhou Chongwu 
Published: May 2020

AbstractRed phosphorus offers a high theoretical sodium capacity and has been considered as a candidate anode for sodium-ion batteries. Similar to silicon anodes for lithium-ion batteries, the electrochemical performance of red phosphorus is plagued by the large volume variation upon sodiation. Here we perform in situ transmission electron microscopy analysis of the synthesized red-phosphorus-impregnated carbon nanofibers with the corresponding chemo-mechanical simulation, revealing that, the sodiated red phosphorus becomes softened with a “liquid-like” mechanical behaviour and gains superior malleability and deformability against pulverization. The encapsulation strategy of the synthesized red-phosphorus-impregnated carbon nanofibers has been proven to be an effective method to minimize the side reactions of red phosphorus in sodium-ion batteries, demonstrating stable electrochemical cycling. Our study provides a valid guide towards high-performance red-phosphorus-based anodes for sodium-ion batteries.
Spin-controlled generation of indistinguishable and distinguishable photons from silicon vacancy centres in silicon carbide
Authors: Morioka Naoya , Babin Charles , Nagy Roland , Gediz Izel , Hesselmeier Erik , Liu Di , Joliffe Matthew , Niethammer Matthias , Dasari Durga , Vorobyov Vadim , Kolesov Roman , Stöhr Rainer , Ul-Hassan Jawad , Son Nguyen Tien , Ohshima Takeshi , Udvarhelyi Péter , Thiering Gergő , Gali Adam , Wrachtrup Jörg , Kaiser Florian 
Published: May 2020

AbstractQuantum systems combining indistinguishable photon generation and spin-based quantum information processing are essential for remote quantum applications and networking. However, identification of suitable systems in scalable platforms remains a challenge. Here, we investigate the silicon vacancy centre in silicon carbide and demonstrate controlled emission of indistinguishable and distinguishable photons via coherent spin manipulation. Using strong off-resonant excitation and collecting zero-phonon line photons, we show a two-photon interference contrast close to 90% in Hong-Ou-Mandel type experiments. Further, we exploit the system’s intimate spin-photon relation to spin-control the colour and indistinguishability of consecutively emitted photons. Our results provide a deep insight into the system’s spin-phonon-photon physics and underline the potential of the industrially compatible silicon carbide platform for measurement-based entanglement distribution and photonic cluster state generation. Additional coupling to quantum registers based on individual nuclear spins would further allow for high-level network-relevant quantum information processing, such as error correction and entanglement purification.
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities
Authors: Nichols Caitlin A. , Gibson William J. , Brown Meredith S. , Kosmicki Jack A. , Busanovich John P. , Wei Hope , Urbanski Laura M. , Curimjee Naomi , Berger Ashton C. , Gao Galen F. , Cherniack Andrew D. , Dhe-Paganon Sirano , Paolella Brenton R. , Beroukhim Rameen 
Published: May 2020

AbstractAlterations in non-driver genes represent an emerging class of potential therapeutic targets in cancer. Hundreds to thousands of non-driver genes undergo loss of heterozygosity (LOH) events per tumor, generating discrete differences between tumor and normal cells. Here we interrogate LOH of polymorphisms in essential genes as a novel class of therapeutic targets. We hypothesized that monoallelic inactivation of the allele retained in tumors can selectively kill cancer cells but not somatic cells, which retain both alleles. We identified 5664 variants in 1278 essential genes that undergo LOH in cancer and evaluated the potential for each to be targeted using allele-specific gene-editing, RNAi, or small-molecule approaches. We further show that allele-specific inactivation of either of two essential genes (PRIM1 and EXOSC8) reduces growth of cells harboring that allele, while cells harboring the non-targeted allele remain intact. We conclude that LOH of essential genes represents a rich class of non-driver cancer vulnerabilities.
Observing atomic layer electrodeposition on single nanocrystals surface by dark field spectroscopy
Authors: Hu Shu , Yi Jun , Zhang Yue-Jiao , Lin Kai-Qiang , Liu Bi-Ju , Chen Liang , Zhan Chao , Lei Zhi-Chao , Sun Juan-Juan , Zong Cheng , Li Jian-Feng , Ren Bin 
Published: May 2020

AbstractUnderpotential deposition offers a predominant way to tailor the electronic structure of the catalytic surface at the atomic level, which is key to engineering materials with a high activity for (electro)catalysis. However, it remains challenging to precisely control and directly probe the underpotential deposition of a (sub)monolayer of atoms on nanoparticle surfaces. In this work, we in situ observe silver electrodeposited on gold nanocrystals surface from sub-monolayer to one monolayer by designing a highly sensitive electrochemical dark field scattering setup. The spectral variation is used to reconstruct the optical “cyclic voltammogram” of every single nanocrystal for understanding the underpotential deposition process on nanocrystals, which cannot be achieved by any other methods but are essential for creating novel nanomaterials.