bluuebunny/crossref_metadata_2025_split huggingface dataset:
KORELASI HEALTH BELIEF DENGAN KEPATUHAN PEMBATASAN CAIRAN DAN GARAM PADA PASIEN PENYAKIT GINJAL KRONIK YANG MENJALANI HEMODIALISA DI RUMAH SAKIT MURNI TEGUH MEDAN
Authors: Kasiman Kalvin Ginting Sutomo , Siregar Cholina Trisa 
Published: September 2020

know that they suffer from a disease, they will take more serious care for their health and take medication in accordance with doctors’ recommendation. However, there are still many patients with CKD do not comply with the doctors’ recommendation. Health belief is the belief adhered in undergoing medication will affect the believers’ health. The objective of this research was to analyze the correlation of health belief with fluid and salt restriction compliance in patients with CKD undergoing hemodialysis. This research employed quantitative design with cross sectional method. There were 150 patients with CKD undergoing hemodialysis in total that were taken as the samples. This research was conducted at Murni Teguh Hospital, Medan. The samples were selected by applying total accidental technique. The data were collected through questionnaires, and the analysis was made by using Pearson test. The results of Pearson test on the correlation of health belief with patients’ fluid and salt restriction compliance demonstrated value of p = 0.000. It indicated that health belief are correlated with the fluid and salt restriction compliance of patients with CKD undergoing hemodialysis. It is recommended that nurses improve their education quality and frequency by paying attention to patients.
Gender of internal medicine resident impacts cancer preventive care for women
Authors: Hefley Shyanne , L Vasylyeva Tetyana , Salguero Maria , Al-Humaish Saif , Cutts Karen , Smalligan Roger 
Published: September 2020

Mammography and cervical screening are effective methods for early cancer detection in women. Recent reports showed that 69% of women ³45 years had a mammogram in the past 2 years and 16-55% of women had a Pap smear regularly. Internal medicine (IM) physicians are crucial players in women's health management and literature has identified that a physician’s gender impacts patient management in many areas of healthcare.
We investigated mammogram and Pap smear recommendations by IM residents and examined differences in approaching women’s health issues between female and male residents. With IRB approval, one-hundred charts of new female patients were reviewed, which included female patients 45 years or older seen by IM residents for their first visit. All patients completed a questionnaire concerning previous medical conditions and care as part of clinic routine. Patient chart information, recommendations for mammogram and cervical cancer screening by the resident were recorded, along with the gender of the resident and supervising attending.
The mean age of the patients was 61±9.3 years. Female residents were more likely to recommend a mammogram compared to male residents (36.7% and 16.4%, respectively). No significant differences in Pap smear recommendations were observed between female and male residents (9.3% and 10.1%, respectively). Attending physician’s gender did not influence screening recommendations.
The recommendation rate for female patients to obtain important screening mammograms and Pap smears was low. These results are consistent with previous literature and indicate an urgent need for improved women’s health education in residency, with special attention to male residents.

Keywords: Cancer prevention, Breast cancer, Cervical Cancer, Primary Care, Gender Disparity
L’Alsace dans la Grande Guerre
Authors: Grandhomme Jean-Noël 
Published: September 2020

En 2013, un siècle après l’affaire de Saverne – qui apparaît rétrospectivement comme une sorte de prologue de la Grande Guerre –, un groupe d’historiens confirmés et de jeunes chercheurs entend faire le point sur l’état des connaissances concernant un conflit qui a eu une importance toute particulière pour l’Alsace. Événements militaires, mais aussi politiques, économiques, sociaux, vie quotidienne des soldats et des civils seront évoqués tour à tour dans ce volume. La question de la mémoire et des enseignements à tirer du conflit ne sera pas oubliées non plus.
Profils des entreprises utilisatrices de voitures de société en Région de Bruxelles-Capitale
Authors: Ermans Thomas 
Published: September 2020

Sur base des données des Plans de déplacements d’entreprise de la RBC (2014), nous avons mis en évidence trois profils d’entreprises utilisatrices de voitures de société. Ces dernières sont définies comme l’ensemble des entreprises avec au-moins 10 voitures de société pour 100 travailleurs, un seuil qui exclut la quasi-totalité des administrations publiques ainsi que les secteurs de la santé et de l’enseignement. Au-delà de l’élaboration de profils particuliers, cette factsheet met en évidence le rapport de corrélation, d’association, entre la mise à disposition de voitures de société au bénéfice des travailleurs et d’autres caractéristiques. Spécifiquement, le recours aux voitures de société concourt, avec une mise à disposition généreuse de places de parking et une mauvaise accessibilité en transports en commun, à dessiner des profils de mobilité à l'échelle de l’entreprise globalement tournés vers l’usage du mode automobile sur les déplacements domicile-travail.
Remarques sur la création plurilingue chez Fernando Pessoa
Authors: Dionísio João 
Published: September 2020

L’observation du fonds Fernando Pessoa (1888-1935) à la Bibliothèque nationale du Portugal permet de mettre en évidence deux types de recours à d’autres systèmes linguistiques que la langue maternelle de l’écrivain portugais (1888-1935) : 1) annotations métadiscursives, inclusivement des indications de création littéraire, dont un nombre significatif en anglais ; 2) l’abandon de la langue dans laquelle il commence à écrire un texte (l’anglais ou le français, langues occasionnelles d’inspiration initiale) pour continuer en portugais. Ce type de bilinguisme manifeste dans le processus créatif est mis en rapport avec la vision idéaliste que Pessoa a de la poésie, qui, selon lui, « doit être composée et exprimée dans une langue quelconque », comme si toute création littéraire était le résultat de la traduction du langage de l’esprit vers une langue naturelle.
Mechanistic Studies on Propargyl Alcohol‐Tethered Alkylidenecyclopropane with Aryldiazonium Salt Initiated by Visible Light
Authors: Liu Jiaxin , Wei Yin , Shi Min 
Published: September 2020

Main observation and conclusionThis paper discloses the reaction mechanism of two consecutive but different visible light photo‐induced chain processes for the rapid construction of spirobi[indene] skeletons. The first process is triggered by a photo‐induced single‐electron‐transfer (SET) of an electron donor‐accepter (EDA) complex. The second process is initiated by a direct SET process between aryldiazonium salt and the excited allenic intermediate. In these two processes, another SET took place respectively on the in situ formed radical intermediate to realize a redox‐neutral outcome. The mechanistic studies have been carried out by control experiments, kinetic and spectroscopic analyses, deuterium labeling experiments to support these two chain processes.
Inviscid Limit of Vorticity Distributions in the Yudovich Class
Authors: Constantin Peter , Drivas Theodore D. , Elgindi Tarek M. 
Published: September 2020

AbstractWe prove that given initial data , forcing and any T > 0, the solutions uν of Navier‐Stokes converge strongly in for any p ∈ [1, ∞) to the unique Yudovich weak solution u of the Euler equations. A consequence is that vorticity distribution functions converge to their inviscid counterparts. As a by‐product of the proof, we establish continuity of the Euler solution map for Yudovich solutions in the Lp vorticity topology. The main tool in these proofs is a uniformly controlled loss of regularity property of the linear transport by Yudovich solutions. Our results provide a partial foundation for the Miller‐Robert statistical equilibrium theory of vortices as it applies to slightly viscous fluids. © 2020 Wiley Periodicals LLC.
Applicability of Chromatographic Co‐Elution for Antibiotic Target Identification
Authors: Schäkermann Sina , Wüllner Dominik , Yayci Abdulkadir , Emili Andrew , Bandow Julia Elisabeth 
Published: September 2020

AbstractIdentification of the molecular target is a crucial step in evaluating novel antibiotics. To support target identification, a label‐free method based on chromatographic co‐elution has previously been developed. Target identification by chromatographic coelution (TICC) exploits the alteration of the elution profile of target‐bound drug versus free drug in ion exchange (IEX) chromatography to identify potential target proteins from elution fractions. The applicability of TICC for antibiotic research is investigated by evaluating which proteins, that is, putative targets, can be monitored in Bacillus subtilis. Coelution of components of known protein complexes provides a read‐out for how well the native state of proteins is conserved during chromatography. Rifampicin, which targets RNA polymerase, is used in a proof‐of‐concept study.
Itraconazole attenuates the stemness of nasopharyngeal carcinoma cells via triggering ferroptosis
Authors: Xu Ying , Wang Qian , Li Xiaozhen , Chen Yingyan , Xu Gang 
Published: September 2020

AbstractRadiotherapy is a common therapy method for nasopharyngeal carcinoma (NPC) treatment; however, radioresistance greatly limits the clinical efficiency and prognosis of NPC patients. Therefore, it is extremely urgent to reveal the underlying mechanism contributing to radioresistance and find possible diagnostic biomarkers. Here, we collected the spheroids formed by NPC cells, which had been confirmed to hold the stem cell‐like traits, and found that these spheroids exhibited a certain degree of radioresistance. Additionally, NPC spheroids displayed a certain degree of ferroptosis resistance, as evident by the decrease of iron concentration in lysosomes and lipid peroxides oxygen, and increase of glutathione (GSH) level. Furthermore, we revealed that itraconazole triggered the ferroptosis of NPC spheroids, which is characterized as the increase of iron concentration and lipid peroxides oxygen, and decrease of GSH level, and decreased the cell viability of NPC spheroids. Notably, itraconazole partially reversed the radioresistance of NPC spheroids. Mechanistically, we found that itraconazole can sequester iron in lysosome and thus trigger ferroptosis; this is essential for itraconazole‐mediated attenuation on NPC spheroid stemness. Therefore, this study provides evidences showing that itraconazole might be used for killing NPC stem cells and thus attenuate radioresistance.
Uncovering the ecology of clinical education: a dramaturgical study of informal learning in clinical teams
Authors: Cantillon Peter , De Grave Willem , Dornan Tim 
Published: September 2020

AbstractOff-the-job faculty development for clinical teachers has been blighted by poor attendance, unsatisfactory sustainability, and weak impact. The faculty development literature has attributed these problems to the marginalisation of the clinical teacher role in host institutions. By focusing on macro-organisational factors, faculty development is ignoring the how clinical teachers are shaped by their everyday participation in micro-organisations such as clinical teams. We set out to explore how the roles of clinical teacher and graduate learner are co-constructed in the context of everyday work in clinical teams. Using an ethnographic study design we carried out marginal participant observation of four different hospital clinical teams. We assembled a dataset comprising field notes, participant interviews, images, and video, which captured day-to-day working and learning encounters between team members. We applied the dramaturgical sensitising concepts of impression management and face work to a thematic analysis of the dataset. We found that learning in clinical teams was largely informal. Clinical teachers modelled, but rarely articulated, an implicit curriculum of norms, standards and expectations. Trainees sought to establish legitimacy and credibility for themselves by creating impressions of being able to recognise and reproduce lead clinicians’ standards. Teachers and trainees colluded in using face work strategies to sustain favourable impressions but, in so doing, diminished learning opportunities and undermined educational dialogue. These finding suggest that there is a complex interrelationship between membership of clinical teams and clinical learning. The implication for faculty development is that it needs to move beyond its current emphasis on the structuring effects of institutional context to a deeper consideration of how teacher and learner roles are co-constructed in clinical teams.
Does Sea Surface Temperature Affect Solubility of Iron in Mineral Dust? The Gulf of California as a Case Study
Authors: Félix‐Bermúdez Armando , Delgadillo‐Hinojosa Francisco , Torres‐Delgado Eunise V. , Muñoz‐Barbosa Albino 
Published: September 2020

AbstractEolian transport of mineral dust is one of the main inputs of iron (Fe) to the global ocean; however, the magnitude and biogeochemical impact of this supply depends on the solubility of the deposited dust. In particular, the effect of temperature on Fe‐bearing dust solubility has been scarcely investigated even though a seasonal gradient of sea surface temperature (SST) is a common feature in coastal zones adjacent to the major dust source regions of the world. In this work, the effect of temperature on the fractional solubility of Fe (FFeS) was evaluated experimentally using sieved soils (as a dust proxy) from the Baja California Peninsula and surface seawater from the Gulf of California (GC). Two incubations were performed at 17°C (winter) and 29°C (summer) considering the seasonal variability of SST in the GC. Differences in FFeS up to 3 orders of magnitude (0.003–4.49%) were linked to incubation temperature, dust load, and contact time between seawater and dust. After 72 hr of incubation, the effect of temperature was statistically significant (p < 0.05) for all dust treatments, with FFeS higher (4–24 times) at 29°C. High FFeS in warmer waters are a result of increased Fe‐bearing dust dissolution and decreased scavenging of Fe by dust particles. Since temperature appears to control the magnitude of FFeS in the GC, we suggest that this factor could have an effect on the atmospheric inputs of soluble Fe in marginal seas with similar seasonal SST contrasts; including the global ocean, where well‐defined latitudinal temperature gradients exist.
Handheld endomicroscope using a fiber-optic harmonograph enables real-time and in vivo confocal imaging of living cell morphology and capillary perfusion
Authors: Hwang Kyungmin , Seo Yeong-Hyeon , Kim Daniel Y. , Ahn Jinhyo , Lee Soyoung , Han Kyung Hee , Lee Koun-Hee , Jon Sangyong , Kim Pilhan , Yu Kate E. , Kim Hyungsin , Kang Shin-Hyuk , Jeong Ki-Hun 
Published: September 2020

AbstractConfocal laser endomicroscopy provides high potential for noninvasive and in vivo optical biopsy at the cellular level. Here, we report a fully packaged handheld confocal endomicroscopic system for real-time, high-resolution, and in vivo cellular imaging using a Lissajous scanning fiber-optic harmonograph. The endomicroscopic system features an endomicroscopic probe with a fiber-optic harmonograph, a confocal microscope unit, and an image signal processor. The fiber-optic harmonograph contains a single mode fiber coupled with a quadrupole piezoelectric tube, which resonantly scans both axes at ~ 1 kHz to obtain a Lissajous pattern. The fiber-optic harmonograph was fully packaged into an endomicroscopic probe with an objective lens. The endomicroscopic probe was hygienically packaged for waterproofing and disinfection of medical instruments within a 2.6-mm outer diameter stainless tube capable of being inserted through the working channel of a clinical endoscope. The probe was further combined with the confocal microscope unit for indocyanine green imaging and the image signal processor for high frame rate and high density Lissajous scanning. The signal processing unit delivers driving signals for probe actuation and reconstructs confocal images using the auto phase matching process of Lissajous fiber scanners. The confocal endomicroscopic system was used to successfully obtain human in vitro fluorescent images and real-time ex vivo and in vivo fluorescent images of the living cell morphology and capillary perfusion inside a single mouse.
PARTICULATE MATTER FROM SYRINGES USED FOR INTRAVITREAL INJECTIONS
Authors: Dounce Susan M. , Laskina Olga , Goldberg Roger A. 
Published: September 2020

Background:
Syringes containing anti-vascular endothelial growth factor drugs to treat retinal diseases are prepared in different ways by various parties with syringe selection, preparation, and storage conditions affecting the risk of injecting particles into the vitreous. This study examines particle loads from various syringes over time.

Methods:
Four syringes were studied: two plastic transfer syringes lubricated with silicone oil or oleamide, a glass syringe with baked-on silicone, and a lubricant-free polymer syringe. Syringes were rinsed with water or filled with buffer and analyzed over time; particles were quantified by flow imaging. Particle formation in a bevacizumab formulation was also characterized.

Results:
Insulin syringes consistently showed very high particle counts. Oleamide-lubricated syringes had substantially fewer particles, but showed appreciable increases over time (leading to visible particles). Baked-on silicone glass syringes and lubricant-free polymer syringes both showed low particle levels ≥10 μm. Lubricant-free syringes showed the lowest particle levels ≥1 μm and the lowest particle levels with bevacizumab agitation.

Conclusion:
Syringes have different intrinsic particle loads which can contribute to particle loads in the delivered drug. Oleamide-lubricated transfer syringes, commonly used for bevacizumab repackaging, have time-dependent particle loads and are associated with the formation of visible particles beyond 30 days of storage.
Efficiency of azathioprine monotherapy for maintenance treatment of autoimmune hepatitis in children
Authors: Aksoy Betul , Baran Masallah , Cagan Appak Yeliz , Sag Elif , Cakir Murat , Guven Burcu , Yavuz Sibel , Emir Busra , Tumgor Gokhan 
Published: September 2020

Introduction
Autoimmune hepatitis (AIH) is a common pediatric liver disease and long-term remission is usually maintained with low dose prednisolone and azathioprine (AZA). The aim of this study is to evaluate the efficiency of AZA monotherapy for maintenance treatment of children with AIH.

Materials and methods
This study was a retrospective analysis of the 55 children with AIH. Patients were divided into two groups: combination therapy (CT) and AZA group based on maintenance therapy. Results of these two different maintenance treatments were compared in children with AIH.

Results
The mean age of the children was 10.67 ± 4.30 years (61.8% females) with a mean follow-up period of 46.8 ± 33.6 months. For maintenance treatment, 39 (70.9%) patients received AZA and 16 (29.1%) patients received CT. Relapse was observed in nine (19.6%) cases in the follow-up period; two were in the CT group (2/16; 12.5%) and seven (7/39; 17.9%) were in the AZA group (P = 0.620). In AZA group, the duration of remission was 22.2 ± 6.1 months and that was longer than CT group (P = 0.025).

Conclusion
Our study suggests that AZA monotherapy is an effective and safe therapy for maintaining remission in children with AIH. AZA monotherapy may be used for maintenance treatment of children with AIH, except in cases of overlap syndrome and also to avoid side effects of long-term used steroids and to improve treatment compliance in proper cases.
Psychological defense mechanisms and use of corporeal discourse: a comparison between patients with irritable bowel syndrome, medical personnel and healthy volunteers
Authors: Reicher-Atir Rebecca , Avnat-Becker Lee , Levy Sigal , Sperber Ami D. , Dickman Ram 
Published: September 2020

Objective
The aim of this study was to compare the use of psychological defense mechanisms and corporeal discourse among patients with irritable bowel syndrome (IBS), medical personnel and healthy volunteers.

Methods
All participants completed an identical battery of questionnaires: a demographic questionnaire, the Corporeal Discourse Questionnaire, the Defense Style Questionnaire and a Visual Analogue Scale for situational anxiety and depression. Patients and medical personnel were recruited from the Rabin Medical Center, a tertiary university-affiliated hospital. Findings were analyzed according to the study variables and compared among the groups.

Results
Questionnaires were completed by 40 patients with IBS, 39 medical personnel and 40 healthy volunteers. Correlations between the study variables within the entire study group (all study participants, N = 119) revealed that corporeal discourse was found to be significantly correlated with the immature and neurotic class of defense mechanisms (r = 0.41, P < 0.01 and r = 0.20, P < 0.05, respectively), depression (r = 0.46, P < 0.05) and anxiety (r = 0.46, P < 0.05). Differences between IBS and the other two groups were significant for corporeal discourse, depression, anxiety and use of immature defense mechanisms. Posthoc analyses showed that medical personnel differed from IBS patients in all of these measures. Healthy volunteers had an inconsistent pattern of differences from the other two groups.

Conclusion
Maturity level of defense mechanisms and the tendency to use corporeal discourse are expressed among IBS patients in a diverse and unique manner. These findings may indicate additional psychological mechanisms that could explain the use of somatic complaints in IBS and support the implementation of tailored psychological interventions.
Reconstruction of Craniofacial Skin Cancer Resection Defect in Octogenarian Patients Using Fenestrated-type Artificial Dermis Without Skin Grafting
Authors: Chicco Maria , Cheng Hsu-Tang 
Published: September 2020

Abstract
Reconstructive surgery following skin cancer resection in octogenarian patients can be challenging. Despite current advancements in reconstructive options, most of these wide excision defects require local or even free flap coverage, causing physical and emotional impairment. Few reports have been published on the management of these complex craniofacial defects. We present our experience in 2 octogenarian patients with craniofacial skin cancer treated with wide excision under wide-wake local anesthesia and subsequently reconstructed with fenestrated-type artificial dermis. Both patients had uneventful recovery. The wounds healed by secondary intention without skin grafting.