bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Xanthomonas campestris pv. campestris on the growth of etiolated and photosynthetic seedlings of Brassica oleracea
Authors: Ushakov A. A. , Kozar E. G. , Engalycheva I. A. 
Published: December 2019

Relevance. In recent years, physiologists are very interested in studying the characteristics of the growth and development of seedlings under conditions of etiolation. Etiolated seedlings, as a model object, are interesting in studying the responses of a plant organism to the effects of various biotic environmental factors. In this regard, a comprehensive study of the characteristics of the influence of Xanthomonas campestris pv. campestris (Хсс) on growth processes in the early stages of development of white cabbage plants, depending on the racial composition of the pathogen, is very important.Material and method. The study was carried out on the basis of the immunity and plant protection laboratory of the Federal State Budgetary Scientific Institution of the Federal Scientific Vegetable Center (FSVC). The material of research were seeds of two varieties of white cabbage with different resistance to vascular bacteriosis and four races of Xanthomonas campestris pv. campestris (Хсс1, Хсс3, Хсс4 и Хсс6). Sterile seeds of each variety were laid out in Petri cups. Infection with different races of Xcc was carried out by introducing into each Petri cup 1 ml of a bacterial suspension of a two-day culture at a concentration of 106 cells/ml. Half of the Petri cups were placed in a thermostat without illumination, the other was exposed to light under a 16- hour regime of illumination with diffused light. The magnitude and orientation of biological effects of studied factors on biometric parameters of seedlings were evaluated by the relative deviation of the difference between parameters of the experimental and control variants.Results. A different degree of influence of the resistance of the variety and the aggressiveness of the pathogen race on the growth of individual parts of the seedling has been established, and the response of etiolated and photosynthetic seedlings to infection is often the opposite. In the susceptible cultivar Slava 1305, acceleration of root and hypocotyl growth in the dark (Хсс3, Хсс4 and Хсс1) and inhibition of these processes in the light (Хсс1, Хсс4 and Хсс6) were noted. Relatively stable SB-3 F1 hybrid has more pronounced raspecificity of the effect of Xcc on root growth and stimulation of hypocotyl growth in all variants, which was 2-8 times lower in etiolated seedlings when infected with Xcc6 and Xcc1 races than in light ones, and when infected by the races Xcc1 and Xcc4, the effect was comparable.
Comparative assessment of the nature of the impact of ultraviolet radiation on watermelon seeds in time mode
Authors: Gulin A. V. , Donskaya V. I. 
Published: December 2019

Relevance. One of the main components of the spectrum of sunlight is ultraviolet rays – invisible to the human eye short-wave radiation. The influence of these rays on plant life was considered insignificant until recently, but recent studies have shown the fallacy of such conclusions. Ultraviolet has a beneficial effect not only on the human body and animals, but also on plants, including – crops. The destruction of the ozone layer is currently continuing under the influence of anthropogenic factors. In this regard, the study of the effect of ultraviolet radiation on living organisms, including plants, is very relevant from both theoretical and practical points of view. The epidermis of plant leaves and seed shells are permeable to medium-and long-wave UV radiation, so of particular interest is the ultraviolet radiation of the Sun and artificial sources of ultraviolet radiation in the range of 400...180 nm.Purpose of work: to assess the nature of the impact of ultraviolet radiation in the time mode on watermelon seeds using cytogenetic analysis.Methods. The material for research was the seeds of the watermelon variety "Astrakhan". The studies were conducted in 2017-2018.Results. The results of studies have shown that long-term exposure to ultraviolet radiation can affect the physiological processes and anatomical structure of plants, as well as have serious genetic changes: aneuploidy, cytotomy, pyknosis and various chromosomal aberrations that lead to mutations or death of plants. However, plants acquire useful mutations with short-term exposure-0.5-2 hours, which can be used later in selection.
Metodologia da pesquisa em competência em informação
Authors: Silva Carlos Robson Souza da , Teixeira Thiciane Mary Carvalho , Pinto Virginia Bentes 
Published: December 2019

As pesquisas relacionadas à temática levaram à proliferação de modelos de Competência em Informação, utilizados como quadro de referência, para aplicação em outras pesquisas ou na prática bibliotecária. Tendo isso em vista, questiona-se: quais foram os modelos de Competência em Informação utilizados como quadro de referência em dissertações e teses defendidas em Programas de Pós-Graduação em Ciência da Informação, no período de 2014 a 2018? O presente trabalho tem como objetivo geral: identificar os modelos de Competência em Informação utilizados com mais frequência na pesquisa sobre Competência em Informação no Brasil. E como objetivos específicos: a) apresentar um panorama da pesquisa brasileira sobre Competência em Informação; b) apresentar as principais tendências na produção de teses e dissertações sobre Competência em Informação no Brasil; c) realizar uma revisão sistemática da pesquisa brasileira em nível de Mestrado e Doutorado em Ciência da Informação entre 2014-2018. Trata-se de uma pesquisa exploratória, de abordagem qualitativa, que utiliza como método de pesquisa bibliográfica a revisão sistemática dos resultados obtidos em levantamento realizado na Biblioteca Digital de Teses e Dissertações (BDTD) do Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT). Conclui apontando para o fato de que os modelos de Competência em Informação são tidos como essenciais para o desenvolvimento da pesquisa sobre a temática e servem como fundamentação teórica e metodológica para a crítica, a interpretação e aplicação de conceitos e métodos sobre Competência em Informação.
Synthesis, Cytotoxicity, Xanthine Oxidase Inhibition, Antioxidant of New Pyrazolo{3,4 d}Pyrimidine Derivatives
Authors: Et al. Khammas 
Published: December 2019

Allopurinol derivative were prepared by reacting the (1-chloroacetyl)-2-Hydropyrazolo{3,4-d}pyrimidine-4-oneiwith 5- methoxy- 2-aminoibenzothiazoleiunder certain conditions to obtain new compound ( N- (2-aminoacetyl (5-methoxy) benzothiazole -2yl) (A4), Reaction of 5-(P-dimethyl amine benzene)-2-amino-1,3,4- oxadiazole in the presence of potassium carbonate anhydrous to yield new compound (N-(2- aminoacetyl-5-(P-dimethyl amine benzene )-1,3,4-oxadiazoles-2-yl)(A30) and Azo compound (N-(5-(Azo-2-hydroxy-5-amino benzene)-1,3-Diazol-2yl)Allopurinol(A46). The structure of prepared compounds were confirmed by (FT-IR) technique and their physical properties. The synthesized compounds were tested for cytotoxicity, Xanthine oxidase inhibition, and antioxidant activity.
Spectrophotometric Determination of Mesalazine in Pharmaceutical Preparations by Oxidative Coupling Reactions with m-Aminophenol and 2,6- Dihydroxybenzoic Acid
Authors: Et al. Aziz 
Published: December 2019

Tow simple, rapid and sensitive spectrophotometric methods for the determination of mesalazine in pharmaceutical preparations have been carried out. The proposed methods depend on oxidative coupling reaction of mesalazine with m-aminophenol in the existence of N-bromosuccinamide in alkaline medium (method A) and 2,6-dihydroxybenzoic acid in the existence of sodium metaperiodate in basic medium (method B) to produce colored products , show highest absorptions at 640 (nm) and 515 (nm), alternately. Beer’s law was consistent in concentrations extent of 1.25-30 and 0.5-12.5 (µg.mL-1) with molar absorptivity of 0.36×104 and 0.77×104 L.mol-1.cm-1, alternately. The limits of detection (LOD) were 0.0144 and 0.0829 µg.mL-1, while limits of quantitation (LOQ) were 0.0483 and 0.2766 (µg.mL-1), alternately. The suggested methods have been applied successfully to the determination of mesalazine in its pharmaceutical preparations as tablets and suppositories.
Effect of the Dielectric Barrier Discharge Plasma on the Optical Properties of CDS Thin Film
Authors: Jebur Eman Kadum 
Published: December 2019

Cadmium sulphide CdS films with 200 nm have been prepared by thermal evaporation technique on glass substrate at substrate room temperature under vacuum of 10-5mbar.In this paper, the effect of Dielectric Barrier Discharge plasma on the optical properties of the CdS film. The prepared films were exposed to different time intervals (0, 3, 5, 8) min. For every sample, the Absorption A, absorption coefficient α , energy gap Eg ,extinction coefficient K and dielectric constant ε were studied. It is found that the energy gap were decreased with exposure time, and absorption , Absorption coefficient, refractive index, extinction coefficient, dielectric constant increased with time of exposure to the plasma. Our study considers the first investigation of the effect of cold atmospheric plasma on the optical properties of CdS film.
Grado de microfiltración en sellantes dentales usados en premolares con dos tratamientos de superficie dental
Authors: Herrera-Cuadros SF , Albites-Achata U 
Published: December 2019

OBJETIVO: Comparar in vitro el grado de microfiltración de los sellantes en premolares humanos con la técnica de aire abrasivo y ameloplastía como preparación de superficie. METODOLOGÍA: Se realizó un estudio in vitro en premolares humanos, se agruparon en 3 grupos de 25 piezas: Control, ameloplastía con fresa de fisura y aire abrasivo con partículas de aluminio de 110µm. Se realizó la preparación de superficie de acuerdo al grupo y se aplicaron los sellantes dentales, se termociclaron 500 ciclos (5° y 55°C) por 30 segundos en las temperaturas mínima y máxima, posteriormente fueron sumergidos durante 24 horas en azul de metileno al 1%, seccionados bucolingualmente y evaluados en un estereomicroscopio a 16x. Se usó la prueba chi cuadrado a un nivel de significancia de 0.05. RESULTADOS: En el grupo control se observó que 7 (28%) no filtraron, 9 (36%) filtraron menos de 500µm y 9 (36%) más de 500µm. En el grupo preparado con ameloplastía con fresa de fisura, 6(24%) no filtraron, 7 (28%) filtraron menos de 500µm, y 12 (48%) filtraron más de 500um. Finalmente, en la técnica con aire abrasivo, 3 (12%) no filtraron, 7 (28%) filtraron menos de 500µm, y 15 (60%) filtraron más de 500µm. No hubo asociación significativa p= 0.482 CONCLUSIÓN: El grado de microfiltración de sellantes en premolares no está asociado con la técnica de preparación de superficie, sin embargo se observó menor microfiltración en el grupo control seguido de ameloplastia y finalmente de aire abrasivo.
Efecto del tiempo de grabado con ácido fosfórico al 37.5% sobre la superficie de esmalte haciendo uso de agentes cementantes autoadhesivos.
Authors: Ascurra Francia Liliana , Saravia-Rojas M A 
Published: December 2019

OBJETIVO: Comparar la resistencia traccional de resina compuesta adherida a la superficie del esmalte de bovino en diferentes intervalos de tiempos de 15 y 30 segundos haciendo uso de ácido grabador en tres agentes cementantes autoadhesivos y un grupo control. MATERIALES Y MÉTODOS: Fueron utilizados treinta y cinco incisivos inferiores sanos de bovino menor de 3 años, los cuales fueron divididos aleatoriamente en siete grupos correspondientes a cada cemento autoadhesivo y tiempo de grabado ácido: RelyX U200 (3M) (grupo U15”) (grupo U30”), Bis Cem (BISCO)(grupo B15”)(grupo B30”), MaxCem Elite (KERR)(grupo M15”)(grupo M30”), RelyX Ultimate (3M)(grupo UL) se procedió a la cementación con los bloques de resina compuesta como se indica el protocolo previo grabado ácido del esmalte de 15 y 30 segundos para cada cemento . Los especímenes de 1 mm2 de área transversal (n = 30 por grupo) se almacenaron en agua destilada por 24 horas a 36 °C. La prueba de microtensión se realizó haciendo uso del Microtensile Tester (Bisco). Para el análisis estadístico se utilizaron las pruebas de Kruskal Wallis y U Mann Whitney (p<0.05). RESULTADOS: El grupo U 30” presentó una resistencia promedio de 24.82 (±3.80) MPa; el U 15”, 23.40 (±5.80 ) MPa, el M30”,30.86 (±9.85) MPa, el M15”, 28.29 (±2.02) MPa, el B 30”, 17.42(±3.49) MPa, el B15”,17.63 (±3.61) MPa, y el UL, 31.53 (±6.39 ) MPa, encontrando diferencia significativa entre ellos (p < 0.001) a través del análisis de Kruskal Wallis . CONCLUSIÓN: El cemento Relyx Ultimate obtuvo el valor más alto de resistencia traccional encontrándose diferencias estadísticamente significativas con todos cementos autoadhesivos. No se encontraron diferencias estadísticamente significativas al comparar los dos tiempos de grabado ácido de 15 y 30 seg. en esmalte entre los grupos de cementos autoadhesivos, al cabo de 24 horas.
Digitized Uncertainty Handling of Pore Pressure and Mud-Weight Window Ahead of Bit: North Sea Example
Authors: Lothe Ane E. , Cerasi Pierre , Aghito Manuel 
Published: December 2019

SummaryA digitized workflow from predrill pore-pressure modeling with a Monte Carlo approach until update of the pressure prognosis while drilling from (for example) sonic or resistivity data is described. The approach has the potential to reduce the uncertainty in the predicted mud-weight window ahead of the bit.For the 3D pressure modeling, a basin modeling software is used, where the pressure compartments in the study area are defined by faults interpreted from seismic. Pressure generation and dissipation are calculated for the study area over millions of years, as the basin was subsiding and compaction was taking place. Key input parameters such as minimum horizontal stress, vertical stress, and frictional coefficients for failure criteria are varied. The output is pore-pressure profiles along the planned well path, with uncertainties.The work presented in this paper was carried out on a North Sea data set. The results show that the uncertainty in the pore pressures will highly influence the uncertainty span in both the fracture gradient and the collapse gradient. Representing the mud-weight window in terms of the most likely collapse and fracturing curve, with corresponding minimum and maximum pore-pressure-derived limits on each side, makes for a more realistic prediction. It presents the uncertainty in the result in a simple visual form, using a “traffic light” approach.While drilling, log data will automatically be used to update the pressure and mud-weight prognosis ahead of bit. The digital updated prognosis can help the drilling crew in decision making during drilling campaigns.
Evaluating the Performance of Surfactants in Enhancing Flowback and Permeability after Hydraulic Fracturing through a Microfluidic Model
Authors: Liang Tianbo , Xu Ke , Lu Jun , Nguyen Quoc , DiCarlo David 
Published: December 2019

Summary
Hydraulic fracturing can create a large fracture network that makes hydrocarbon production from low-permeability reservoirs economical. However, water can invade the rock matrix adjacent to the created fractures and generate water blockage that impairs production. Using surfactants as fracturing-fluid additives is a promising method to enhance the fluid flowback, and thus mitigate the water blockage caused by invasion. It is imperative to understand how surfactants work during the fracturing and production stages, so as to maximize their effectiveness in production enhancement. In this study, an experimental investigation is conducted using a “chipflood” sequence that simulates fluid invasion, flowback, and hydrocarbon production from hydraulically fractured reservoirs. All experiments are conducted in a 2.5D glass micromodel that provides direct observation of in-situ phase changes when different Winsor types of microemulsions formed in the porous medium. The results provide direct evidence of the impact of the matrix–fracture interaction as well as water removal when surfactants are used. They further elucidate why surfactants under different Winsor-type conditions perform differently in mitigating the water blockage. This helps to clarify the screening criteria for optimizing flowback surfactant in hydraulic fracturing.
Emergence delirium and intranasal dexmedetomidine premedication in pediatric anesthesia: a retrospective study in plastic surgery
Authors: Palma Alessandra Di , Maldarelli Federica , Cimino Antonietta , Zama Mario , Picardo Sergio Giuseppe 
Published: December 2019

Abstract

Background Dexmedetomidine is increasingly used in the treatment of emergency delirium (ED) in pediatric patients. However, further evidence on its use in pediatric anesthesia and on potential differences in the reduction of ED according to patient’s age and type of anesthesia is required. Moreover, whether dexmedetomidine influences time of discharge from the surgical area remains unclear. We evaluated whether intranasal dexmedetomidine is effective in decreasing the incidence of ED in 106 children who had anesthesia for plastic surgery undergoing general or combined anesthesia at different ages. We also assessed if this drug has an impact on time to discharge from the surgical area. Methods In total, 106 children, aged 2–10 years, were enrolled in this retrospective study. Among them, 50 have been premedicated with dexmedetomidine (dexmedetomidine group); the remaining 56 patients served as controls (control group). The incidence of ED was evaluated according to the use of dexmedetomidine premedication, age and type of anesthesia (general vs combined). The length of anesthesia and duration of staying in the surgical area were also analyzed. Results Three patients who received dexmedetomidine premedication showed ED (6%), compared with 43 patients in the control group (77%; p<0.05). This lower incidence of ED was also present when stratifying patients according to the type of anesthesia or age. We observed no significant difference between the dexmedetomidine group and control group in terms of discharge from surgical area. Conclusions Premedication with dexmedetomidine is associated with decreased incidence of ED, regardless of patients’ age or type of anesthesia and without seemingly increasing the timing of discharge after surgery.
Development and validation of a predictive model for composite adverse outcomes in primary postpartum haemorrhage in a low-resource setting, Mpilo Central Hospital, Bulawayo, Zimbabwe.
Authors: Ngwenya Solwayo 
Published: December 2019

Abstract
BackgroundPrimary postpartum haemorrhage remains an important cause of maternal mortality and morbidity globally. It is difficult to predict. There are very few predictive models on composite adverse outcomes on postpartum haemorrhage that are available in the literature. The aim of this study was to develop and validate multivariable predictive model to assist clinicians in decision-making after a diagnosis of postpartum haemorrhage is made, and to prevent the development of composite adverse outcomes.MethodsThis was a retrospective cross-sectional study that covered the period from 1 July 2016 to 30 November 2019, at Mpilo Central Hospital. The study included participants that had a diagnosis of postpartum haemorrhage within 24 hours of delivery at Mpilo Central Hospital. The independent variables included socio-demographic factors, laboratory tests, clinical outcomes, causes and the management of PPH. The outcome of interest for this research was composite adverse outcome in PPH. Predictor variables that had a p<0.2 from the bivariate correlations analyses were considered for the multivariable stepwise backward logistic regression. Performance of the model was assessed with a calibration slope. Discrimination ability was evaluated using the area under curve of the receiver operating characteristic (AU ROC). Internal validation of the model was assessed using bootstrap method. ResultsThe final predicted probability model for composite adverse maternal outcomes was; logit (logarithm of the odds) (pi) = 0.141 + (2.35 x 10-1 x blood loss) + (-1.18 x 10-1 x platelets) + (0.57 x 10-1 x parity) + (2.27 x 10-1 x ruptured uterus).The model was well calibrated. The discrimination ability of the model was excellent. The AU ROC curve was 0.890 (95% CI 0.830-0.949, p<0.0001). Internal validation was by bootstrapping, and the model was still a good fit for the data with a p<0.0001.ConclusionsA predictive model for composite adverse outcomes in PPH was developed. It had a good discriminatory ability, with an AU ROC of 0.890 (95% CI 0.830-0.949). This predictive model for composite adverse outcomes could help clinicians to be alerted to which women with PPH are most likely to develop composite adverse outcomes thereby preventing maternal deaths.
Pharmacokinetics Alterations in Critically Ill Pediatric Patients on Extracorporeal Membrane Oxygenation: A Systematic Review
Authors: Sutiman Natalia , Koh Janine Cynthia , Watt Kevin , Hornik Christoph , Murphy Beverly , Chan Yoke Hwee , Lee Jan Hau 
Published: December 2019

Abstract
BACKGROUNDTo identify alterations in pharmacokinetics in children on extracorporeal membrane oxygenation (ECMO), identify knowledge gaps and inform future clinical pharmacology studies.METHODSWe systematically searched the following databases from earliest publication until November 2018: MEDLINE, CINAHL and EMBASE, using a controlled vocabulary and keywords related to: “ECMO”, and “pharmacokinetics”, “pharmacology”, “drug disposition”, “dosing” and “pediatrics”. Inclusion criteria were: study population aged <18 years, supported on ECMO for any indications, receiving any medications while on ECMO and reported pharmacokinetics data. Clearance and/or volume of distribution (Vd) values were extracted from the included studies.RESULTS41 studies (total patients=574) evaluating 23 drugs met the inclusion criteria. The most common drugs studied were anti-microbials (n=13), and anticonvulsants (n=3). 28 studies (68%) were conducted in children < 1 year of age. 33 studies (80%) were conducted without intra-study comparisons to non-ECMO controls. Increase in Vd attributable to ECMO was demonstrated for 9 (56%) drugs: cefotaxime, gentamicin, piperacillin/tazobactam, fluconazole, micafungin, levetiracetam, clonidine, midazolam and sildenafil (range: 23-345% increase relative to non-ECMO controls), which may suggest the need for higher initial dosing. Decreased Vd was reported for 2 drugs: acyclovir and ribavirin (50 and 69%, respectively). Decreased clearance was reported for gentamicin, ticarcillin/clavulanate, bumetanide and ranitidine (range: 26-95% decrease relative to non-ECMO controls). Increased clearance was reported for caspofungin, micafungin, clonidine, midazolam, morphine and sildenafil (range: 25-455% increase relative to non-ECMO controls).CONCLUSIONSThere were substantial pharmacokinetic alterations in 70% of drugs studied in children on ECMO. However, studies evaluating pharmacokinetic changes of many drug classes, and those that allow direct comparisons between ECMO and non-ECMO patients, are still lacking. Systematic evaluation of pharmacokinetic alterations of drugs on ECMO that incorporate multi-drug opportunistic trials, physiologically based pharmacokinetic modeling, ex-vivo studies and other methods are necessary for definitive dose recommendations.