bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KEPATUHAN DIET HIPERTENSI DI PUSKESMAS ASTAMBUL
Authors: Martini Nur Sukmawaty , Maria Insana , Mawaddah Norlatifah Sarifatul 
Published: November 2020

Latar Belakang: Hipertensi atau yang lebih dikenal dengan sebutan penyakit darah tinggi adalah suatu keadaan dimana tekanan darah seseorang berada di atas batas normal atau optimal yaitu 120 mmHg untuk sistolik dan 80 mmHg untuk diastolik. Tingkat pengetahuan seseorang disinyalir memiliki hubungan yang cukup kuat untuk menginisiasi aksi kepatuhan seseorang untuk menjalankan diet. Tujuan penelitian ini adalah untuk mengetahui hubungan tingkat pengetahuan dengan kepatuhan diet hipertensi pada penderita hipertensi di Puskesmas Astambul.
Metode: Penelitian ini menggunakan metode deskriptif analitik dengan desain penelitian korelasi dengan teknik purposive sampling, dengan jumlah populasi 5.823 orang dan jumlah sampel sebanyak 98 orang.
Hasil: Penelitian ini menunjukkan hasil uji statistik 0,000 < 0,05 yang berarti H0 gagal diterima, artinya ada hubungan antara tingkat pengetahuan dengan kepatuhan diet hipertensi di Puskesmas Astambul pada tahun 2019.
Kesimpulan: Penelitian ini menunjukkan ada hubungan antara tingkat pengetahuan dengan kepatuhan diet hipertensi pada pasien dengan masalah hipertensi di Puskesmas Astambul, Kalimantan Selatan. Penelitian ini menunjukkan bahwa petugas kesehatan perlu memberikan intervensi seperti memberikan saran kepada keluarga yang mempunyai anggota keluarga yang menderita penyakit hipertensi untuk memeriksa anggota keluarganya bila sudah ada tanda dan gejala hipertensi.
PENGARUH TERAPI FOOT MESSAGE TERHADAP KECEMASAN PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISA DI RSUD ULIN BANJARMASIN
Authors: Amaludin Mimi Mimi , Hamzah Hamzah , Muhsinin Muhsinin 
Published: November 2020

Latar Belakang: Kecemasan merupakan masalah psikososial yang dapat berdampak buruk terhadap prognosis penyakit pasien Tujuan penelitian ini mengidentifikasi pengaruh terapi foot massage terhadap kecemasan pada pasien gagal ginjal kronis yang menjalani hemodialisa di Rumah Sakit Ulin Banjarmasin
Metode: Penelitian ini menggunakan desain quasi experiment dengan metode pre-posttest with control group design. Sampel dipilih secara puposive sampling yang berpedoman kepada kriteria penelitian,
Hasil: Sebanyak 40 responden telah dipilih dalam penelitian ini untuk mengikuti terapi foot message dengan karakteristik usia 46-55 tahun (72,5%), jenis kelamin laki-laki (60%), tingkat pendidikan SMA 67,5%), mayoritas responden sudah bekerja (80%) dengan lama menjalani hemodialisis < 1 tahun (67,5%). Responden yang telah diberikan terapi foot massage menunjukan penurunan skor kecemasan secara signifikan dengan nilai p 0,000. Perbedaan yang bermakna juga ditemukan antara kelompok yang diberikan terapi foot message dengan kelompok kontrol dengan nilai p 0,014.
Kesimpulan: Kecemasan pada pasien gagal ginjal kronis yang menjalani hemodialisa merupakan masalah yang harus segera diatasi. Pemberian terapi foot massage merupakan langkah awal dalam upaya mengurangi kecemasan pada pasien yang menjalani hemodialisis.
Kata Kunci: Foot Massage, Gagal Ginjal Kronis, Hemodialis, Kecemasan
ANALISIS FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KUALITAS PENGELOLAAN PEMBELAJARAN KLINIK
Authors: AHMAD ERWAN , Yani Achir , Azidin Yustan 
Published: November 2020

Latar Belakang: Pembelajaran klinik merupakan pembelajaran berbasis pengalaman, mahasiswa diharapkan mampu mengaplikasikan teori yang diperoleh dari akademik pada kasus-kasus nyata di klinik. Manfaat pembelajaran klinik mendapatkan pengalaman nyata untuk mencapai kemampuan profesional (intelektual, teknikal, dan interpersonal).
Tujuan: Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kualitas pembelajaran klinik (kompetensi pembimbing, pengaturan bimbingan, metode pembelajaran, lingkungan pembelajaran, dan lahan praktik)
Metode: Sampel penelitian ini adalah 84 mahasiswa ners angkatan 2018 Universitas Muhammadiyah Banjarmasin. Teknik pengambilan sampel yang digunakan adalah Total Populasi
Hasil: Uji statistik menunjukkan bahwa terdapat empat hubungan dengan kualitas pembelajaran klinik yaitu komptensi pembimbing, pengaturan bimbingan, metode pembelajaran dan lingkungan pembelajaran dengan p value <0,05 dan faktor yang paling dominan adalah kompetensi pembimbing dengan nilai probability sebesar 2,820. Bidang manajemen pendidikan perlu memperhatikan kompetensi dosen pada saat rekrutmen dosen dilakukan berdasarkan pemenuhan persyaratan kualifikasi.
PENGARUH PEER EDUCATION TERHADAP PENGETAHUAN KEHAMILAN PADA KELAS IBU HAMIL
Authors: Rusdiana Rusdiana , Maria Insana 
Published: November 2020

Latar Belakang: Salah satu indikator keberhasilan pembangunan kesehatan di Indonesia adalah menurunnya angka kematian ibu, salah satu caranya dengan metode Peer Education atau kelompok teman sebaya. Penelitian ini bertujuan untuk mengetahui pengaruh Peer Education terhadap pengetahuan perawatan kehamilan pada kelas ibu hamil di wilayah kerja Puskesmas Astambul
Metode : Jenis penelitian ini adalah Quasi Eksperimen, Penelitian dilaksanakan di Wilayah Kerja Puskesmas Astambul, teknik sampling yang digunakan adalah random sampling, dengan populasi ibu hamil sebanyak 657 orang, sampel ibu hamil sebanyak 15 orang. Instrumen yang digunakan dalam penelitian ini adalah kusioner dengan jumlah 15 soal. Teknik analisis data menggunakan uji Uji Statistik: Uji Paired T Test.
Hasil : Hasil Penelitian sebelum dilakukan penyuluhan perawatan kesehatan responden dengan tingkat pengetahuan baik berjumlah 67%, setelah dilakukan penyuluhan meningkat menjadi 93,3% responden dengan tingkat pengetahuan baik yang menandakan adanya pengaruh Peer Education terhadap tingkat pengetahuan.
Kesimpulan: Adanya pengaruh peer education terhadap pengetahuan perawataan kehamilan pada kelas ibu hamil di wilayah kerja Puskesmas Astambul, maka penting memberikan informasi tentang perawatan ibu hamil terutama oleh tenaga kesehatan.

Kata kunci : Peer Education, Kelas Ibu Hamil
HUBUNGAN PENATALAKSANAAN PEMBERIAN CAIRAN DIRUMAH DENGAN TINGKAT DEHIDRASI PADA BALITA YANG MENGALAMI DIARE
Authors: Zubaidah Zubaidah , Maria Insana 
Published: November 2020

Latar Belakang : Penyebab utama kematian diare adalah dehidrasi akibat kehilangan cairan dan elektrolit melalui feses, Penatalaksanaan penyakit diare yaitu dengan cara pemberianterapi cairan yang adekuat untuk mencegah terjadinyadampak lebih lanjut dari diare yaitu anak akan mengalami dehidrasi. Tujuan penelitian untuk mengetahui hubungan penatalaksanaan pemberian cairan dirumah dengan tingkat dehidrasi pada balita yang mengalami diare.
Metode:. Penelitian ini menggunakan metode analitik. Populasi yang digunakan orang tua yang balitanya sedang mengalami diare sebanyak 65 orang. Pengambilan sampel menggunakan tehnik accidental Sampling yaitu 40 responden. Analisis univariat dengan pengumpulan data berupa tabel distribusi frekuensi dan analisis bivariate menggunakan uji Sperman Rank.
Hasil : Hasil uji statistic spearman rho diperoleh nilai p = 0,000, yang berarti Ho ditolak dan Ha diterima terdapat hubungan antara penatalaksanaan pemberian cairan dirumah dengan tingkat dehidrasi. Mayoritas responden dapat melakukan penatalaksanaanpemberian cairan dengan kategori cukup (62,5%), tingkat dehidrasi pada balita mayoritas repondenmengalami diare tanpa dehidrasi (57,5%).
Kesimpulan: terdapat hubungan antara penatalaksanaan pemberian cairan dirumah dengan tingkat dehidrasi maka diharapkan bagi orang tua agar selalu memberikan cairan yang tepat ketika balita mengalami diare dan apabila kondisi balita tidak segera membaik maka secepatnya balita dibawa kepelayanan kesehatan terdekat.

Kata Kunci : Penatalaksanaan pemberian cairan dirumah,balita, diare, tingkat dehidrasi
Výplň týlní deprese sesuvu mezi Židlochovicemi a Blučinou na severozápadním okraji Výhonu
Authors: Hanáček Martin , Petřík Jan , Bíšková Jarmila , Bíško Richard , Adameková Katarína , Lenďáková Zuzana 
Published: November 2020

The studied area is located in a small basin between between Strže („Cézavy“) and Výhon hills. The „Cézavy“ site is an important Bronze Age enclosed settlement. Geological setting was examined by coring and electric resistivity tomography. Selected horizons were dated by C14 method. Holocene infill of basin is composed of two sedimentary units: intra-basin facies of dark coloured lacustrin-swamp clayey-silty sediments and marginal facies of clayey-silty-sandy sediments. Basin of assymetrical shape is deepest near foothill of „Cezávy“, where started infilling of basin as soon as ~3600 BP or earlier. The basin is delimited by bodies of Miocene rocks. Geochronological model shows existence of swamps-lacustrine basins in a time span since 17th century BC till 18th centuriy AD. It indicates, that main cause that filled the basin is individual landslides. Every landslide event caused new spatial configuration of basins and elevations. Last significant events were probably extensive, historically recorded landslides in 70‘s of 18th century. Recent morphology was formed as late as in 19th century.
Addition of L-cysteine to the N- or C-terminus of the all-D-enantiomer [D(KLAKLAK)2] increases antimicrobial activities against multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Escherichia coli
Authors: Ohno Maki K. , Kirikae Teruo , Yoshihara Eisaku , Kirikae Fumiko , Ishida Isao 
Published: November 2020

Background
Antimicrobial peptides have a broad spectrum of antimicrobial activities and are attracting attention as promising next-generation antibiotics against multidrug-resistant (MDR) bacteria. The all-d-enantiomer [D(KLAKLAK)2] has been reported to have antimicrobial activity against Escherichia coli and Pseudomonas aeruginosa, and to be resistant to protein degradation in bacteria because it is composed of D-enantiomer compounds. In this study, we demonstrated that modification of [D(KLAKLAK)2] by the addition of an L-cysteine residue to its N- or C- terminus markedly enhanced its antimicrobial activities against Gram-negative bacteria such as MDR Acinetobacter baumannii, E. coli, and P. aeruginosa.

Methods
The peptides [D(KLAKLAK)2] (DP), DP to which L-cysteine was added at the N-terminus C-DP, and DP to which L-cysteine was added at the C-terminus DP-C, were synthesized at >95% purity. The minimum inhibitory concentrations of peptides and antibiotics were determined by the broth microdilution method. The synergistic effects of the peptides and the antibiotics against MDR P. aeruginosa were evaluated using the checkerboard dilution method. In order to assess how these peptides affect the survival of human cells, cell viability was determined using a Cell Counting Kit-8.

Results
C-DP and DP-C enhanced the antimicrobial activities of the peptide against MDR Gram-negative bacteria, including A. baumannii, E. coli, and P. aeruginosa. The antimicrobial activity of DP-C was greater than that of C-DP, with these peptides also having antimicrobial activity against drug-susceptible P. aeruginosa and drug-resistant P. aeruginosa overexpressing the efflux pump components. C-DP and DP-C also showed antimicrobial activity against colistin-resistant E. coli harboring mcr-1, which encodes a lipid A modifying enzyme. DP-C showed synergistic antimicrobial activity against MDR P. aeruginosa when combined with colistin. The LD50 of DP-C against a human cell line HepG2 was six times higher than the MIC of DP-C against MDR P. aeruginosa. The LD50 of DP-C was not altered by incubation with low-dose colistin.

Conclusion
Attachment of an L-cysteine residue to the N- or C-terminus of [D(KLAKLAK)2] enhanced its antimicrobial activity against A. baumannii, E. coli, and P. aeruginosa. The combination of C-DP or DP-C and colistin had synergistic effects against MDR P. aeruginosa. In addition, DP-C and C-DP showed much stronger antimicrobial activity against MDR A. baumannii and E. coli than against P. aeruginosa.
Multi‐Channel Pumped Ultrasonic Spray‐Coating for High‐Throughput and Scalable Mixed Halide Perovskite Solar Cells
Authors: Guo An‐Zhe , Chou Li‐Hui , Yang Shun‐Hsiang , Wang Dan , Wang Xiao‐Feng , Osaka Itaru , Lin Hao‐Wu , Liu Cheng‐Liang 
Published: November 2020

AbstractThe upscaling of perovskite solar cells to achieve high‐throughput and highly efficient photovoltaic devices is still challenging. In this work, spray deposition of MAPbI3‐xBrx mixed halide perovskite is achieved using a ternary channel pumping system to deposit methylammonium iodide, PbI2, and PbBr2 precursor solutions. The compositions of six kinds of perovskite films (x = 0–0.5) are manipulated by adjusting the flow rate of the syringe pump rather than through traditional methods of preparing and changing the chemical management of the halogen precursors. Large clusters in highly oriented crystalline perovskite films are fabricated as MAPbI2.91Br0.09 film (x = 0.09) with a champion power conversion efficiency (PCE) of 15.60%. When vacuum‐assisted thermal annealing is used, the optimized PCE increased further up to 17.07%. To confirm the homogeneity of the perovskite film over the large area (7 × 10 cm2), eight divided subcells with dimensions of 2.5 × 2.5 cm2 showed the highest and average PCE of 17.11% and 16.25 ± 0.77%, respectively. These findings highlight the relevance of high‐throughput screening of perovskite compositions and the versatility of scalable solution process, in which active layers are deposited by spray‐coating.
Aggregation‐Dependent Chromism and Photopolymerization of Aminoanthraquinone‐Substituted Diacetylenes
Authors: Bisht Rajesh , Dhyani Vartika , Jelinek Raz 
Published: November 2020

AbstractPolydiacetylenes have attracted significant interest for their unique chromatic properties and applications in sensing, imaging, and optics. Here, it is demonstrated that aminoanthraquinone‐substituted diacetylenes exhibit distinct aggregation‐dependent chromatic properties, affected by the alignment of both the aminoanthraquinone headgroups and diacetylene sidechains. Specifically, it is shown that aminoanthraquinone‐diacetylene monomers adopt different film organizations depending upon the polarity of the solvent employed for predissolution. In particular, a yellow aminoanthraquinone‐diacetylene phase, which undergoes photopolymerization upon ultraviolet irradiation, is produced upon dissolution in polar organic solvents prior to deposition and drying on solid substrates. In contrast, a red phase that can not be polymerized is observed when the monomers are predissolved in apolar solvents. Microscopic and spectroscopic analyses indicate that the optical properties of the films are determined by the degree of overlap between the aminoanthraquinone headgroups as well as the alignment of the diacetylene sidechains; both factors are intimately affected by interactions of the monomers with solvent molecules. It is shown that the aggregation‐dependent diacetylene films exhibit remarkable solvochromic, thermochromic, and mechanochromic properties. The aminoanthraquinone‐substituted diacetylenes may facilitate chromatic tuning of polydiacetylene systems in the solid state, determined by solvent‐ and intermolecular interactions and concomitant self‐assembly of the pendant sidechains and aromatic headgroups.
2D Allotrope of Carbon for Self‐Powered, Flexible, and Transparent Optoelectronics
Authors: Guo Yujie , Zhang Luhong , Jin Dan , Lu Yangfan , Xu Zhenyu , Jiang Jinchun , Yang Ziyu , Liang Huawei , Fang Hui , Ruan Shuangchen , Zeng Yu‐Jia 
Published: November 2020

AbstractFlexible and transparent optoelectronics based on 2D materials are promising candidates for next‐generation technologies. Among all 2D materials, it is of numerous practical implications to explore nonmetal, earth‐abundant candidates. Herein, an exciting addition is unearthed—2D hydrogenized amorphous carbon (α‐C:H). The 2D α‐C:H nanosheets, with layered structural feature, are composed of crystalline sp2 nanoclusters embedded in sp3 amorphous matrix. The typical “vapor–solid” mechanism governs the growth of these nanosheets under the temperature–pressure combination above the Berman–Simon line. Their high transmittance over 97.7% covers the 425–1300 nm wavelength region. Optical characterizations also reveal a spectral overlap between the π–π* absorption edge and σ–σ* photoluminescence peak. Self‐powered and flexible photodetectors based on the 2D α‐C:H/ZnO heterostructure exhibit a remarkable photoresponse, with a broadened photosensitivity responsivity of 195.16 mA W−1 and a 267‐fold decrease of the rise time. This performance enhancement originates from the type II band alignment, the pyroelectric and piezo‐phototronic effects. As a new member in the 2D family, α‐C:H nanosheets promise to be appealing in transparent flexible optoelectronics with ultralow power consumption and real‐time, on‐site response.
Photon‐ and Charge‐Management in Advanced Energy Materials: Combining 0D, 1D, and 2D Nanocarbons as well as Bulk Semiconductors with Organic Chromophores
Authors: Cadranel Alejandro , Haines Philipp , Kaur Ramandeep , Menon Arjun , Münich Peter W. , Schol Peter R. , Guldi Dirk M. 
Published: November 2020

AbstractIn this contribution, seminal works in the area of photon‐ and charge‐management are highlighted with focus on covalent electron donor‐acceptor conjugates built around porphyrins (Ps), on one hand, and 0D, 1D, and 2D nanocarbons, on the other hand. Photons in these conjugates are managed by Ps, while 0D, 1D, and 2D nanocarbons serve as the active component, which enable managing charges. With a few leading examples, it can be explored much beyond the simple photon‐ and charge‐management characterization and emphasize photovoltaics and photocatalysis to convert and store energy. This contribution concludes by highlighting recent progress in mixing and matching the unique charge‐management features of nanocarbons in the design of multidimensional nanocarbons.
A C‐S‐C Linkage‐Triggered Ultrahigh Nitrogen‐Doped Carbon and the Identification of Active Site in Triiodide Reduction
Authors: Chang Jiangwei , Yu Chang , Song Xuedan , Tan Xinyi , Ding Yiwang , Zhao Zongbin , Qiu Jieshan 
Published: November 2020

AbstractAn efficient chemical synthesis route, with an aim of reaching an ultrahigh nitrogen (N)‐doping level in carbon materials can provide a platform where the type and amount of N dopant can be tuned over a wide range. We propose a C‐S‐C linkage‐triggered confined‐pyrolysis strategy for the high‐efficiency in situ N‐doping into carbon matrix and an ultrahigh doping level up to 13.5 at %, which is close to the theoretical upper limit (15.2 at %) is realized at a high carbonization temperature of 1000 °C. The pyridinic N is dominant with a maximum percent of 48.7 %. By using I3− reduction as an example, the resultant NCM‐5 exhibits the best activity with a power conversion efficiency of 8.77 %. A pyridinic N site‐dependent activity is demonstrated in which the amount of active sites increases with the increase of pyridinic N, and the carbon atom adjacent to electron‐withdrawing pyridinic N at the armchair edge acts as the most favorable site for the adsorption of I2.
A Concise Total Synthesis of (−)‐Berkelic Acid
Authors: Cheng Hong‐Gang , Yang Zhenjie , Chen Ruiming , Cao Liming , Tong Wen‐Yan , Wei Qiang , Wang Qingqing , Wu Chenggui , Qu Shuanglin , Zhou Qianghui 
Published: November 2020

AbstractReported here is a concise total synthesis of (−)‐berkelic acid in eight linear steps. This synthesis features a Catellani reaction/oxa‐Michael cascade for the construction of the isochroman scaffold, a one‐pot deprotection/spiroacetalization operation for the formation of the tetracyclic core structure, and a late‐stage Ni‐catalyzed reductive coupling for the introduction of the lateral chain. Notably, four stereocenters are established from a single existing chiral center with excellent stereocontrol during the deprotection/spiroacetalization process. Stereocontrol of the intriguing deprotection/spiroacetalization process is supported by DFT calculations.
Preventing Retained Surgical Items During Endovascular Procedures: Bridging the Gap Between Guidelines and Practice
Authors: Endicott Kendal M. , Friedrich Rebekah , Custer Jason W. , Sarkar Rajabrata , Rowen Lisa , Anders Megan G. 
Published: November 2020

ABSTRACTA retained surgical item (RSI) can be a devastating and costly procedural complication. Although the current incidence of RSIs is unknown, perioperative personnel routinely perform surgical counts according to their facility’s policies and procedures to prevent this sentinel event. The American College of Surgeons, The Joint Commission, and AORN emphasize the importance of communication and standardized protocols for the counting of surgical items. However, there is a lack of current evidence to support specific recommendations for the counting of items during endovascular procedures. After the occurrence of RSIs during endovascular procedures at our facility, we convened an interdisciplinary workgroup, conducted an analysis of root causes, reviewed the available literature, and revised the existing policy. This article reviews the available literature on RSIs, describes root causes, discusses recommendations from national organizations, and describes the process that we used to create the policy changes at our facility.
Dual EGFR/VEGFR2 inhibitors and apoptosis inducers: Synthesis and antitumor activity of novel pyrazoline derivatives
Authors: Alkamaly Omkulthom M. , Altwaijry Najla , Sabour Rehab , Harras Marwa F. 
Published: November 2020

AbstractNovel derivatives of the pyrazoline scaffold were synthesized and investigated for their cytotoxicity against prostate (PC‐3), hepatocellular (HepG2), and breast (MDA‐MB‐231) carcinoma cells. The most active compounds, 4a, 4b, 5b, and 7c, revealed significant and broad‐spectrum anticancer activities with IC50 values of 1.30–7.18 μM in comparison with doxorubicin (IC50 = 5.12–7.33 μM). Additionally, they exhibited lower cytotoxicity against normal WI‐38 cells, indicating their high safety profiles. Aiming to enlighten the inhibitory potential on receptor tyrosine kinases (RTKs), compounds 4a, 4b, 5b, and 7c were assessed for their activities against four different RTKs (EGFR, FGFR2, HER2, and VEGFR2) and their apoptotic potencies on PC‐3 cells. The results revealed that compounds 5b and 7c are potent dual EGFR and VEGFR2 inhibitors (IC50 = 0.21 and 0.23 μM, respectively, against EGFR; 0.22 and 0.21 μM, respectively, against VEGFR2), whereas they displayed moderate inhibitory activities against HER2 and FGFR2. Besides, compounds 4a, 4b, 5b, and 7c prompted apoptosis via the upregulation of Bax, p53, and caspase‐3, together with the downregulation of the levels of Bcl‐2. Also, it was found that compounds 5b and 7c are more potent as apoptosis inducers than the other tested derivatives. Furthermore, molecular docking analyses of compounds 4a, 4b, 5b, and 7c in the EGFR and VEGFR ATP binding sites were performed, to confirm the in vitro assays.