bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between stroke severity and repolarization parameters in patients with acute ischemic stroke
Authors: ÖZTÜRK Ünal , ÖZTÜRK Önder , TAMAM Yusuf 
Published: October 2019

Purpose: The aim of this study was to investigate the relationship between repolarization parameters and National Institutes of Health Stroke Scale (NIHSS) score in patients with acute ischemic stroke. Materials and Methods: The study comprised 97 patients (males, 42; females, 55; 65 ± 16 years) with acute ischemic stroke. 17 patients were excluded. Patients were divided into two groups based on the calculated NIHSS score (Group 1, NIHSS score &lt; 16; Group 2, NIHSS score ≥ 16). Demographic, clinical, and laboratory data for all patients were collected. A 12-lead resting ECG was recorded at admission to the neurology care unit in patients with acute ischemic stroke and were manually measured with a ruler. QTc, QTd, QTcd, Tpe, Tpe/QT parameters were measured. Results: There were no significant differences among demographic parameters of patients. We found that QTc, QTd, QTcd, Tpe, Tpe/QT parameters were significantly higher in Group 2 than Group 1 patients. Conclusion: In this study, we found that acute ischemic stroke has been shown to cause changes in repolarization parameters. Repolarization parameters are associated with stroke severity on admission in patients with acute ischemic stroke. Increased dispersion of repolarization parameters make independent contributions to the risk of arrhythmic cardiac death in patients with acute ischemic stroke. We suggested that especially severe ischemic stroke patients closely using cardiac monitoring during the first 24 h.
The New ShakeMap in Italy: Progress and Advances in the Last 10 Yr
Authors: Michelini Alberto , Faenza Licia , Lanzano Giovanni , Lauciani Valentino , Jozinović Dario , Puglia Rodolfo , Luzi Lucia 
Published: October 2019

Abstract
This work describes a procedure to configure U.S. Geological Survey (USGS)‐ShakeMap for a given region. The procedure is applied to Italy to update and improve the ShakeMap service provided by Istituto Nazionale di Geofisica e Vulcanologia (INGV). The new configuration features (1) the adoption of recently developed ground‐motion models (GMMs) and of an updated map of VS30 for the local site effects and (2) the adoption of the newly developed USGS‐ShakeMap version 4 (v.4) software (see Data and Resources). We have used the same subdivision in tectonic regimes adopted for the GMMs for the new Italian seismic hazard model (MPS19, Meletti et al., 2017) and selected the most appropriate GMMs after application of a ranking procedure consisting of statistical tests. A cross‐validation technique has been applied to test the goodness of the selected configuration and to compare the ShakeMaps obtained with the old (Michelini et al., 2008) and the new settings. Finally, the INGV ShakeMap workflow has been renovated to exploit the data and analysis chain implemented at INGV from real‐time data streams acquisition to analyst revised waveforms including additional data (e.g., revised location, fault geometry) that may become available days after the event occurrence.
АКТУАЛІЗАЦІЯ КОМПЕТЕНТНІСНОГО ПІДХОДУ У ПРОФЕСІЙНІЙ ОСВІТІ МАЙБУТНІХ ЕКОНОМІСТІВ-ПІДПРИЄМЦІВ
Authors: Кліпа Юлія 
Published: October 2019

Розкрито особливості актуалізації компетентнісного підходу як складової професійної підготовки майбутніх економістів-підприємців. Підкреслюється важливість формування компетенції для ефективної професійної діяльності в умовах сучасного суспільства. Професійна підготовка майбутніх економістів є педагогічним процесом, у результаті якого формується професійна компетентність економіста-підприємця. Узагальнюючи аналіз проблеми, дослідження компетентностей майбутніх економістів-підприємців показує, що педагогічна наука розробила і впроваджує підходи, що дозволяють співвідносити професійну компетентність зі здібностями, уміннями та знаннями. Виділено три основні компетентнісні показники готовності до майбутньої професійної діяльності: мотивація, знання і вміння комунікувати. Автор стверджує, що сучасному економісту-підприємцю потрібні педагогічні знання, уміння і навички, аотже, і освітні компетентності.
ЕКОНОМІЧНЕ ПІДҐРУНТЯ ВИЗНАЧЕННЯ ВАРТОСТІ УСТУПКИ ПРАВА ВИМОГИ ВІДШКОДУВАННЯ ДЛЯ СТОРІН ПРАВОЧИНУ, ВИЗНАНОГО НЕДІЙСНИМ
Authors: Поздняков Юрій , Садовенко Юрій 
Published: October 2019

Установлено найбільш впливові ціноформувальні фактори, що визначають показники вартості нематеріального активу у формі повних або часткових майнових прав щодо уступки права вимоги повернення майна/грошових коштів сторонам угоди, визнаної недійсною в судовому порядку. Зроблено аналіз відповідності отриманого показника вартості майнових прав поняттю справедливої вартості. Визначено теоретичне підґрунтя пропонованої методики у формі базових принципів незалежної оцінки, які є підставою алгоритму визначення кількісних показників вартості майнових прав. Здійснено порівняльний аналіз спільних і відмінних характеристик вартості оцінюваного нематеріального активу, для випадків непогашених взаємних боргових зобов’язань сторін угоди, визнаної нечинною, і стягнення дебіторської заборгованості. На підставі узагальнення результатів виконаного порівняльного аналізу запропоновано загальною методологічною основою для визначення вартості майнових прав щодо уступки права вимоги повернення майна/грошових коштів за угодою купівлі-продажу матеріальних активів, яка визнана недійсною в судовому порядку, вважати методи та оціночні процедури незалежної оцінки, розроблені для оцінки подібного об’єкта оцінки в нематеріальній формі, а саме — дебіторської заборгованості.
МОДЕЛЮВАННЯ СТАНУ ЕКОНОМІЧНИХ СИСТЕМ ВИРОБНИЧОЮ ФУНКЦІЄЮ КОМПЛЕКСНОГО АРГУМЕНТУ
Authors: Русинко Моріка , Костирко Тарас 
Published: October 2019

Розглянуто теоретичні і прикладні аспекти економіко-математичного моделювання виробничої функції комплексного аргументу для оцінки діяльності як окремого підприємства, так і економіки країни в цілому. Виробнича функція представлена лінійною моделлю з дійсними змінними, зв’язки між функцією і змінними описані за допомогою комплексних чисел, на відміну від класичної виробничої функції Кобба — Дугласа. Як змінні розглянуто чисельність зайнятого в економіці населення України і вартість основних засобів, виробнича функція представляє валовий внутрішній продукт. Використаний підхід дозволив провести оцінку впливу ресурсів на виробничу функцію з використанням даних для кожного спостереження, що зняло питання перевірки рядів даних на мультиколінеарність, гетероскедастичність та автокореляційні зв’язки. Проведене дослідження коефіцієнтів використання ресурсів праці і капіталу з 2005-го до 2016 рр. дало змогу оцінити стан економіки країни в цілому, підтвердило явище кризової динаміки у 2010—2014 роках. Починаючи з 2015 року, макроекономічні показники України характеризують повернення до капіталоінтенсивного процесу, який був притаманний економіці країни у період з 2005-го до 2009 рр. Показано, що застосування виробничої функції комплексного аргументу суттєво розширює можливості проведення економічного аналізу процесів, що відбуваються на виробництві.
A Conceptual Framework: Organizational Learning, Competencies, and Innovation in Indonesian Digital Startup
Authors: Tambunan Sihar Tigor Benjamin , Christiananta Budiman , Rachmawati Dyna 
Published: October 2019

Disruptions carried out by digital startups show a big role of technology-based competencies and innovations. In fact, both are the results of organizational learning. This paper explores a conceptual framework that links organizational learning with performance through competency development and innovation in Indonesian digital startups. A combination of literature studies on organizational learning and some previous research compared with a number of factual conditions of digital startups in Indonesia, resulting in intended conceptual framework.
The authors managed to place technology as a prominent element in each of the proposed variables forming a conceptual framework that links organizational learning with digital startup performance. This conceptual study does not compare the concepts of organizational learning and individual learning in digital startups. Supporting facts used in this study are multi-sector digital startups. So this conceptual framework could be different if applied to specific sectors.
Conceptually, organizational learning has the potential to significantly influence the competency development and innovation in Indonesian digital startups.
Does the intra-articular injection of antimicrobials alongside corticosteroids or other medications reduce the risk of synovial sepsis?
Authors: Braid Helen R 
Published: October 2019

PICO question
In horses, does treatment with intra-articular antimicrobials concurrently with intra-articular corticosteroids reduce the risk of iatrogenic synovial sepsis compared to intra-articular corticosteroids alone?
Clinical bottom line
From the current literature, there is no evidence showing that intra-articular injection of antibiotics in conjunction with corticosteroids reduces the risk of synovial sepsis. However, the intra-articular injection of polysulphated glycosaminoglycans (PSGAGs) in combination with corticosteroids was noted as a risk factor for developing iatrogenic synovial sepsis and therefore concurrent antibiotic injection when administering PSGAGs may be warranted. The reported frequency of infection following intra-articular injections was very low (0.02–0.08%). An overall prevalence of iatrogenic synovial sepsis following all intra-articular injections based on data from all included studies was calculated as 0.02% (CI 0.02–0.03%). However, due to the paucity of literature on the topic, further studies are required in this field to determine more accurate clinical recommendations.
Discrete-NTG Truncated Gaussian Simulation: An Alternative Modeling Approach for Coal-Seam-Gas Unconventional Reservoirs, Bowen Basin, Eastern Australia
Authors: Rattazzi Simone , Hansen Alan 
Published: October 2019

Summary
Building a representative static model for predicting and monitoring the performance of coal-seam gas (CSG) fields presents several complex and unique challenges. The individual reservoirs possess different coal architectures, often with highly complex seam splitting, amalgamating, and structural deformation. Our objective was to develop an alternative approach that honored log and core data capturing both the lateral heterogeneity and the vertical signature of the Bowen Basin coals in Central Queensland.
In some areas of the Bowen Basin, coals can be thick and laterally continuous; picking the top and base of each seam works well in small models with homogeneous coals. As seam geometries begin to increase in complexity and coals become more heterogeneous in nature with thinner seams in multiple packages, then a net-to-gross (NTG) approach is often more appropriate. Each method has its merits. The former approach describes the reservoir architecture but implies a certain degree of confidence in coal correlation. In a vast field with complex seam splitting and merging with abundant drilling data, it might not be a practical technique. The NTG method disregards coal-seam architecture and reservoir connectivity.
The proposed workflow is a hybrid approach using discrete modeling algorithms and data-analysis tools on continuous NTG properties. The process operates on a relatively coarse chronostratigraphic framework in which coal is captured as contiguous discrete-NTG “facies.” The use of the truncated Gaussian model ensures the ordering of NTG facies and mimics transitions between coals and the surrounding interburdens. With the adoption of facies vertical proportion trends, we are able to replicate a similar coal-seam signature laterally away from the wellbore. The definition of a categorical coal model allows the proper scaling of seams with different coal-quality characteristics.
With the successful geocellular-model construction and history match of two historical CSG fields in the Bowen Basin, the discrete-NTG truncated Gaussian simulation (TGS) approach has proved to be a valid alternative CSG-modeling technique.
The Impact of the Environment on Quality of Life and Mediating Effects of Sleep and Stress
Authors: Chang Katherine , Wong Frances K. Y. , Chan K. L. , Wong Fiona Y. , Ho H.C. , Wong M.S. , Ho Janice Y. S. , Yuen John W. M. , Siu Judy Y. , Yang Lin 
Published: October 2019

Abstract
Purpose Environment is an independent factor affecting quality of life. Studies suggest that health practices consider having an impact on quality of life. The purpose of the present paper was to examine the association between environmental conditions and quality of life, and how individual health practices affected this association. Methods Participants aged 20 or above were recruited from 11 tertiary planning units in the centre of Kowloon. These tertiary planning units were selected as they represent the overall living environment in Hong Kong, with older poorer urban areas alongside relatively affluent districts. A mediation analysis was implemented using multiple linear regressions to examine the effects of environmental conditions on quality of life. The predictor variables included sociodemographic and environmental conditions, health practices and health service utilisation. Results Of the eligible 607 participants, 390 females and 217 males with a mean age of 47.4 were included for analysis. Physical, psychological and environmental factors were conducive and connected to quality of life. After adjusting for fruit and vegetable intake, gender, education level and chronic illness, perceived stress and sleep quality had significant mediating effects. Conclusion Environment is an important factor that affects the overall well-being of individuals. The interaction of environmental quality with individual variables, specifically stress and sleep is extremely important when assessing its impact on the quality of life. The findings of this study support the importance of individual stress and sleep in mediating the relationship between the environment and quality of life.
A comprehensive analysis of the microbiota composition and gene expression in colorectal cancer
Authors: Zhang Qian , Zhao Huan , Wu Dedong , Cao Dayong , Ma Wang 
Published: October 2019

Abstract
Subject: The dysbiosis of gut microbiota is pivotal in colorectal carcinogenesis. However, the synergy between an altered gut microbiota composition and differential gene expression of specific genes in colorectal cancer (CRC) remains elusive. Method: The gut microbiota dataset with number SRP158779, which contained 19 CRC samples and 19 normal samples, was downloaded from the National Center for Biotechnology Information (NCBI) Sequence Read Archive (SRA) database. The 16S rRNA gene sequences from this dataset were clustered into operational taxonomic units (OTUs); thereafter, the OTUs that were differentially enriched in CRC were identified and classified, followed by prediction of their functions. Additionally, RNA sequencing data from CRC samples was obtained from The Cancer Genome Atlas project (TCGA), and the differentially expressed genes (DEGs) and enriched pathways were identified. Finally, similar pathways that were significantly enriched in both differential OTUs and DEGs were screened. Key genes related to these pathways were executed the prognosis analysis. Results: The presence of Proteobacteria and Fusobacteria increased considerably in CRC samples; conversely, the abundance of Firmicute and Spirochaetes decreased markedly. In particular, the genera Fusobacterium , Catenibacterium , and Shewanella were detectable in tumor samples. Moreover, 246 DEGs were identified between tumor and normal tissues. Both DEGs and microbiota were involved in bile secretion and steroid hormone biosynthesis pathways. Finally, CYP3A4 and ABCG2 expression in CRC was related to the prognostic outcomes of CRC patients. Conclusion: Identifying the complicated interplay between gut microbiota and the DEGs could help in further understanding the pathogenesis of CRC, and these findings would enable better diagnosis and treatment of CRC patients. Keywords: colorectal cancer, gut microflora, gene expression, pathways enrichment, survival analysis
Whole-genome sequencing and genomic-based acid tolerance mechanisms of Lactobacillus delbrueckii subsp. bulgaricus LJJ
Authors: pang xiaoyang , Li Weixun , Yang Lan , Hu Cheng , Lu Jing , Zhang Shuwen , Ujiroghene Obaroakpo Joy , Ma Changlu , Zhang Cai , Lv Jiaping 
Published: October 2019

Abstract
Background: The probiotic efficacy and fermentative ability of Lactobacillus delbrueckii subsp. Bulgaricus ( L. d. bulgaricus ), a widely used probiotic, is majorly affected by its acid tolerance. In this study, a genome-wide sequence of a highly acid-tolerant L. d. bulgaricus LJJ was supposed to be determined, and we expect to find out the acid tolerance mechanism of L. d. bulgaricus LJJ by comparative genomics. Results: Functional annotation and pathways of differential genes were determined using bioinformatics. The results in our study showed that the three genes dapA , dapH and lysC identified are implicated in the high acid tolerance of LJJ strain. Thus, they are potentially important as acid-tolerant genes of LJJ strain. Conclusions: This study successfully revealed the acid tolerance mechanism of LJJ. Based on the previous research of LJJ in our laboratory, the successful analysis of the acid-tolerant mechanism of L. d. bulgaricus will further lay the foundation for the subsequent breeding of high acid-tolerant strains and greatly enhance their probiotic functions. Keywords: Lactobacillus delbrueckii subsp. Bulgaricus ; acid-tolerant mechanism; comparative genomics; dapA ; dapH ; LysC
Does knowledge of danger signs influence use of maternal health services among rural women? Findings from Babati Rural district, Northern Tanzania.
Authors: Shewiyo Edwin Joseph , Mjemmas Minael G , Mwalongo Faidha H , Diarz Ester J. , Msuya Sia E. , Leyaro Beatrice J. 
Published: October 2019

Abstract
Background Increasing knowledge on obstetric danger signs (DS) among pregnant women and their families is one of the interventions targeted to reduce maternal and newborn mortality. It is expected that knowledge in DS will lead to early care seeking once complications occur among women or newborns. Health care providers are required to educate women on DS of obstetric emergency during pregnancy, delivery and immediate-post-delivery. This study aimed to determine the level of knowledge on danger signs among rural women and its effect on antenatal care visits, birth preparedness and complication readiness (BPCR) and on use of skilled birth attendance (SBA) during childbirth.Methodology Community-based analytical cross-sectional study was conducted in July 2019 among women who delivered in the past 24 months in two wards at Babati Rural district, Tanzania. Questionnaire was used for data collection. Odds Ratio was used to assess association between knowledge on danger signs with use of services during pregnancy and childbirth.Results A total of 372 women were enrolled, with mean age of 28.5 years (S.D 7.2). All the women attended antenatal care at least once during pregnancy, 65.3% attended ANC 4 or more visits, 85.2% of women were assisted by SBA during childbirth, and 13.7% of the women had birth preparedness and complication readiness plan. Overall, 272 (73.1%) women reported that they were counseled about obstetric danger signs during antenatal clinic visits, but only 32% could mention three or more DS of obstetric and newborn emergency. Overall good knowledge of DS and knowledge of obstetric danger signs during pregnancy were significantly associated with 4 or more ANC visits and birth preparedness and complication readiness but not with SBA use during childbirth.Conclusion Majority of women were counseled on DS during pregnancy, however more than three quarters (68%) had low knowledge. Women who were knowledgeable on danger signs during pregnancy attended 4+ ANC visits and prepared for birth and its complications. There is a need of designing alternative models of engaging women during education/ counseling sessions so that they may have a higher retention of knowledge not only of danger signs but for other maternal and newborn health issues.
Hypertension and its determinant factors in a Brazilian male working population Hypertension in male workers
Authors: Donato Tamyres Araújo Andrade , Bezerra Vanessa Moraes , Silva Roberta Mendes Abreu , Oliveira Márcio Galvão Guimarães de , Andrade Amanda Cristina de Souza , Kochergin Clavdia Nicolaevna , Soares Daniela Arruda , Medeiros Danielle Souto de , Louzado José Andrade , Silva Kelle Oliveira , Cortes Matheus Lopes , Mistro Sóstenes , Amorim Welma Wildes Cunha Coelho 
Published: October 2019

Abstract
Among men, hypertension stands out as a specific public health problem, as this population has lower rates of treatment, knowledge, and disease control, and less adherence to medication. It was used baseline data from a longitudinal study, conducted with a sample of 1,024 male workers aged 18 years or older from a municipality in Northeast Brazil. Hypertension was defined as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg, and/or prior diagnosis of hypertension and/or use of antihypertensive drugs. Population attributable fractions (PAFs) were calculated for the associated lifestyle factors. The prevalence of hypertension in this population was of 28.6% (95% CI: 25.9-31.5); the distal factors were age, skin color/ethnicity, and household income; intermediate factors: alcohol abuse, tobacco consumption, perception of high salt intake, and physical inactivity; and the proximal factor body mass index were positively associated with hypertension in male workers. Higher PAFs were observed among workers with tobacco and alcohol abuse, perceived high salt intake, physically inactive, and overweight and obese. Is necessary to take specific actions geared to orientation, prevention, and health promotion in workplaces to reduce complications from hypertension and improve lifestyle among this male population.