bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tooth Loss and Nutritional Status in Older Adults: A Systematic Review and Meta-analysis
Authors: Zelig R. , Goldstein S. , Touger-Decker R. , Firestone E. , Golden A. , Johnson Z. , Kaseta A. , Sackey J. , Tomesko J. , Parrott J.S. 
Published: December 2020

Background/Objective: Older adults are at risk for tooth loss and compromised nutritional status. Our objective was to conduct a systematic review and meta-analysis to answer the following question: Among adults aged ≥60 y living in developed countries, what are the associations between tooth loss and nutritional status as assessed by a validated nutrition screening or assessment tool? Methods: PRISMA guidelines were followed. PubMed, Scopus, CINAHL, Web of Science, and MEDLINE were searched for studies published in English between 2009 and 2019 that met inclusion criteria. Data extracted included study and participant characteristics, dentition, and nutritional status. Risk of bias was assessed with a modified Newcastle-Ottawa Scale. Random effects meta-analysis was used. Results: Of the 588 unduplicated articles identified, 78 were reviewed in full text, and 7 met inclusion criteria. Six studies were combined for a meta-analysis, which revealed that individuals who were completely edentulous or who lacked functional dentition had a 21% increased likelihood of being at risk of malnutrition or being malnourished, as compared with those who were dentulous or had functionally adequate dentition (risk ratio, 1.21; 95% CI, 1.11 to 1.32; I2 = 70%). Whether the article statistically adjusted for medical history explained most of the heterogeneity in the pooled effect. Conclusions and Implications: Findings suggest that older adults with tooth loss are at greater risk of malnutrition than those with functionally adequate dentition. Use of validated tools to assess risk of malnutrition in older adults with tooth loss is important to promote early intervention and referral to optimize nutrition and oral health status. Findings were limited by heterogeneity, risk of bias, and overall quality of the studies reviewed. Cohort studies that adjust for known confounders and use consistent approaches to assess tooth loss and nutritional status are needed. Knowledge Transfer Statement: The results of this study suggest that older adults with tooth loss are at greater risk of malnutrition than those with functionally adequate dentition. Screening of this population for malnutrition by health care professionals, including dentists and dietitians, may result in corresponding referrals to optimize nutrition and oral health status. Further research is needed with consistent approaches to assess tooth loss and nutritional status.
Mirror Therapy in Stroke Rehabilitation: Why, How Early, and Effects: A Meta-analysis
Authors: Gandhi Dorcas B. C. , Sterba Albert , Khatter Himani , Pandian Jeyaraj D. , Bhanot Komal 
Published: December 2020

Background and Aims: The use of visual stimuli to facilitate a desired response in the affected limb in mirror therapy (MT) makes it an effective treatment modality even in instances of a complete plegic upper extremity poststroke. This article analyzes the effects of MT on impairments, activity limitation, and participation restriction in the acute and chronic phases poststroke. Methods: In total, 16 out of 3871 studies were included in the meta-analysis, using PRISMA guidelines. Data were categorized based on application in stroke rehabilitation (acute/chronic, motor/sensory/neglect/activity of daily living, upper limb/lower limb), modes and dosage of intervention delivery, types of control, and outcome assessment. RevMan 5.0 software was used for analysis. Results: Studies were equally distributed between chronic and acute phases. Therapy durations lasted between 1 and 8 weeks. Most studies intervened for upper limb motor impairments showing improvement in Brunnstrom motor recovery stages of arm ( P value: .04, 95% CI, 0.05-1.54, I2 = 59%) and hand ( P value: <.001, 95% CI, 0.80-2.01, I2 = 0%) during acute phase (0-4 weeks). “Activity/function” measured by functional independence measure showed improvement only in self-care subsection ( P value: <.001, 95% CI, 2.05-5.16, I2 = 0%). No long-term effects were analyzed in any of the included studies. Conclusion: A significant finding of this study is the role of MT in improving arm and hand impairments in acute phase poststroke. Rehabilitation protocols can be improved based on this finding. As MT is effective, affordable, and feasible, we have made suggestions toward its incorporation in physiotherapy protocols for low- and middle-income countries.
Concordance of patient beliefs and expectations regarding the management of low back pain with guideline recommendations – a cross-sectional study in Germany
Authors: Kiel Simone , Raus Christina , Sierocinski Elizabeth , Knauthe Peggy , Chenot Jean-François 
Published: December 2020

AbstractBackgroundLow back pain is a common reason for patients to seek medical care. Physician non-adherence to clinical guidelines has been observed. We investigated the extent to which patient expectations correspond to recommendations of the German national guideline for management of low back pain (G-LBP) and whether patient characteristics, history of LBP and previous treatment experience are associated with expectations.MethodsA cross-sectional study including patients from 13 general practices was conducted. Data were collected using a questionnaire. Inverse probability weights were used to address non-response bias. Descriptive analysis and multivariate logistic regression models were performed.ResultsA total of 977 patients were included in analyses (median age 57 years, 39% male). 75% of patients reported experiencing LBP currently or within the last year. More than 65% indicated they would agree to forgo further examinations if their LBP was judged by their physician to be of no serious concern. This was associated with the highest level of education and no prior imaging, and negatively associated with good-to-poor health status and moderate-to-severe pain intensity. 40% of participants expected imaging. The highest educational level, female gender and no prior imaging were associated with a decreased expectation of imaging. 70% expected prescriptions for massages. Females, participants with good-to-poor health status, current LBP or LBP in the last 12 months had an increased expectation for massages. Expectations for injection therapy (45%) were mainly associated with previous injections. Expectations for physiotherapy (64%) were associated with female gender, lower educational level, good-to-poor health status, current LBP or in the last 12 months. The perspective that daily activities should be continued (66%) was associated with female gender and higher educational level. Participants who agreed to the statement ‘There is no effective treatment for LBP’ (11%) had a poor health status, current LBP and a severe pain intensity.ConclusionPatient views regarding LBP management are partially concordant with guideline recommendations and are strongly influenced by previous treatment experiences and education level. Exploration of patient expectations and experiences in LBP treatment may help minimize dissatisfaction of patients expecting treatments not endorsed by guidelines and simultaneously increase physician guideline adherence.
SARS-CoV-2 pandemia in Lombardy: the impact on family Paediatricians
Authors: Missaglia Rinaldo , Belingheri Michael , Antolini Laura , de’ Angelis Monica , Brivio Luca , Riva Michele Augusto , Genovesi Simonetta 
Published: December 2020

AbstractAs health care workers (HCWs) who care for children, who usually demonstrate milder symptoms than adults, family paediatricians have an increased risk of exposure to coronavirus. In April 2020, the Sindacato Medici Pediatri di Famiglia (SIMPeF), provided its members with rapid tests to detect antibodies against SARS-CoV-2; 1240 individuals, including 377 paediatricians, 108 staff members of pediatric clinics, and 755 cohabitant relatives of paediatricians, were tested in Lombardy, the most affected Italian region. The global prevalence of IgG antibodies in these individuals was 20.7%, which is higher than that of the general population and other HCWs. More than 70% of subjects with IgG antibodies presented symptoms, and 4.9% needed hospitalization. In addition, 64.2% of the study participants reported close contacts with a suspected case of COVID-19, while 72.9% of the family paediatricians reported occupational exposure to the disease. The initiative of the SIMPeF has been useful in assessing the impact of the COVID-19 pandemic on paediatric settings, as well as in raising paediatricians’ awareness of the spreading of coronavirus.
The insurability of innovative pharmaceutical cancer technologies
Authors: Greenberg Shuli Brammli , Dotan Einat , Arazi Rachel 
Published: December 2020

AbstractThe scientific literature, including several papers published in the IJHPR, has raised the issue of the spiraling cost of cancer treatment, including that of cancer drugs and other technologies such as gene and cell therapies. In this perspective, we review three criteria for insurability and show that they may not be met.First, the uncertain trends in the cost of innovative pharmaceutical and other cancer technologies make the maximum possible loss per event very difficult to predict and to manage in terms of insurer solvency. Second, the uncertainty of the price, the period that a drug or other cancer care technology will be administered and the number of individuals that will need the technology makes it difficult to predict future insurance premiums and whether they will be affordable to the target population. Third, public coverage needs to be consistent with societal values. However, pressure to limit public coverage will gradually increase as the possibilities of innovative pharmaceutical cancer technologies expand, thus transferring the burden onto commercial insurance. This is a phenomenon that is virtually impossible to predict accurately, but which will certainly undermine the status of health as a social good.We conclude that the financial risk arising from the use of innovative pharmaceutical cancer technologies fails to meet the aforementioned criteria, thus raising questions as to the sustainability of commercial insurance for cancer treatment and suggesting the need for the state to take greater responsibility for covering this financial risk in the future.
Refinements of some Hardy–Littlewood–Pólya type inequalities via Green’s functions and Fink’s identity and related results
Authors: Khalid Sadia , Pečarić Josip 
Published: December 2020

AbstractIn this paper, first we present some interesting identities associated with Green’s functions and Fink’s identity, and further we present some interesting inequalities for r-convex functions. We also present refinements of some Hardy–Littlewood–Pólya type inequalities and give an application to the Shannon entropy. Furthermore, we use the Čebyšev functional and Grüss type inequalities and present the bounds for the remainder in the obtained identities. Finally, we use the obtained identities together with Hölder’s inequality for integrals and present Ostrowski type inequalities.
Strong convergence inertial projection and contraction method with self adaptive stepsize for pseudomonotone variational inequalities and fixed point problems
Authors: Jolaoso Lateef Olakunle , Aphane Maggie 
Published: December 2020

AbstractIn this paper, we introduce a new inertial self-adaptive projection method for finding a common element in the set of solution of pseudomonotone variational inequality problem and set of fixed point of a pseudocontractive mapping in real Hilbert spaces. The self-adaptive technique ensures the convergence of the algorithm without any prior estimate of the Lipschitz constant. With the aid of Moudafi’s viscosity approximation method, we prove a strong convergence result for the sequence generated by our algorithm under some mild conditions. We also provide some numerical examples to illustrate the accuracy and efficiency of the algorithm by comparing with other recent methods in the literature.
The burden of injuries in Ethiopia from 1990-2017: evidence from the global burden of disease study
Authors: Ali Solomon , Destaw Zelalem , Misganaw Awoke , Worku Asnake , Negash Legesse , Bekele Abebe , Zergaw Ababi , Walker Ally , Odell Chris , Naghavi Mohsen , Abate Ebba , Mirkuzie Alemnesh H. 
Published: December 2020

Abstract
Background
Mortality caused by injuries is increasing and becoming a significant global public health concern. Limited evidence from Ethiopia on road traffic, unintentional and intentional injuries indicate the potential public health impact of problems resulting from such injuries. However, there is a significant evidence gap about the actual national burden of all injuries in Ethiopia. This data base study aimed to reveal the national burden of different injuries in Ethiopia.

Methodology
Data for this study were extracted from the estimates of the Global Burden of Diseases (GBD) 2017 study. Estimates of metrics such as Disability-Adjusted Life Years (DALYs), death rates, incidence, and prevalence were extracted. The metrics were then examined at different injury types, socio-demographic categories such as age groups and sex. Trends of the metrics were also explored for these categories across years from 2007 to 2017. The DALYs and deaths due to injuries in Ethiopia were also compared with other East African countries (specifically Kenya, Tanzania, Uganda, and Zambia) in order to evaluate regional differences across years, by sex and by different injury types such as transport injuries, unintentional injuries, self-harm and interpersonal violence.

Results
The age-standardized injury death rate has decreased to 69.4; 95% UI: (63.0–76.9) from 90.11; 95% UI: (82.41–97.73) in 2017 as compared with 2007. Road injury, falls, self-harm and interpersonal violence were the leading causes of mortality from injuries occurring in 2017. The age-standardized injury DALYs rate has decreased to 3328.2; 95% UI: (2981.7-3707.8) from 4265.55; 95% UI: (3898.11–4673.64) in 2017 as compared with 2007. The number of deaths resulting from injuries in 2017 was highest for males, children under 5 years, people aged 15–24.

Conclusion
The current age-standardized death rate and DALYs from injuries is high and the observed annual reduction is not satisfactory. There is a difference in gender and age regarding the number of deaths resulting from injuries. The data indicates that the current national efforts to address the public health impact of injuries in Ethiopia are not sufficient enough to bring a marked reduction. As a result, a more holistic approach to address all injuries is recommended in Ethiopia.
Impact of adolescent complex regional pain syndrome on the psychopathology of young men ahead of military service: a retrospective cohort analysis of Korean conscription data
Authors: Lee Shin-Heon , Ko Myeong-Jin , Nam Taek-Kyun , Kwon Jeong-Taik , Park Yong-Sook 
Published: December 2020

Abstract
Background
The relationship between physical and psychopathological features in complex regional pain syndrome (CRPS) has been a subject of constant interest, but no data are available in adolescents. Therefore, we aimed to identify the factors associated with psychopathology in adolescents with CRPS ahead of military service.

Methods
We retrospectively reviewed all conscription examinees who had completed a Military Personality Inventory (MPI) during a period between February 2013 and December 2016. A total of 63 persons with a history of CRPS (19-years of age for all) were enrolled. Basic demographic and pain-related data were analyzed to examine their association with MPI results. The mean FGR score as well as the 8 subdomain scores were compared between those with pain duration at < 15 months (n = 30) versus ≥15 months (n = 33). Binary MPI results (normal-abnormal) were also compared between the two groups.

Results
In multivariate analysis, abnormal MPI was associated with pain duration, with an odds ratio (OR) at 1.05 for every 1-month increase (95% confidence interval (CI) 1.02–1.08; P = 0.002). Subjects with pain duration at ≥15 months have lower faking good response score (P < 0.001 vs. those with pain duration at < 15 months), and higher abnormal MPI result rate, faking bad response, inconsistency, anxiety, depression, somatization, paranoid, personality disorder cluster A, and personality disorder cluster B scores (P < 0.05). Pain duration was significantly associated with the MPI variables.

Conclusions
Pain duration is associated with psychopathology in adolescents with CRPS. Psychopathologic features increased as the disease duration increased. A comprehensive understanding of time-dependent psychopathological factors could support the planning of multimodal approaches for managing adolescent CRPS.
Electro-photoluminescence study in InGaAs/AlGaAs multi-quantum-wells
Authors: Han Lili , Zhao Minglong , Tang Xiansheng , Huo Wenxue , Deng Zhen , Jiang Yang , Wang Wenxin , Chen Hong , Du Chunhua , Jia Haiqiang 
Published: December 2020

Abstract
Photoluminescence (PL) plays an important role in the study of luminescence characteristics of multi-quantum-well (MQW) structures. In this work, we study electro-photoluminescence spectra of InGaAs/AlGaAs MQWs under open-circuit, short-circuit, and forward-voltage conditions. The dependences of photocurrent and photovoltage on excitation power are discussed in this paper, which allows us to explore the carrier behavior in InGaAs/AlGaAs MQW LEDs deeply. We propose that the photovoltaic effect in open-circuit (OC) conditions should be properly considered for PL characterization and calculation of the internal quantum efficiency (IQE) as well as non-radiative recombination (NRA) efficiency in InGaAs/AlGaAs MQW LEDs.
Effect of Different Positions During Surgical Preparation With Combined Spinal-Epidural Anesthesia for Elective Cesarean Delivery: A Randomized Controlled Trial
Authors: Liu Tianyu , Zou Shiya , Guo Lulu , Niu Zheng , Wang Min , Xu Chao , Gao Xiuxiu , Shi Zeshu , Guo Xiaowei , Xiao Hanbing , Qi Dunyi 
Published: December 2020

BACKGROUND:
The intraoperative 15° left-tilt position during cesarean delivery has more recently been questioned regarding its effect on fetal acid-base balance and is a frequent source of complaints by surgeons. We hypothesized that a 30° left-tilt position during surgical preparation could improve the acid-base balance of the fetus compared with the 15° left-tilt or supine position during surgical preparation.

METHODS:
Women undergoing elective cesarean delivery under combined spinal epidural anesthesia were randomized to a supine position, 15° left-lateral tilt position or 30° left-lateral tilt position; the position was changed to supine before the incision. Anesthetic management was standardized and included fluid loading with 10 mL/kg of normal saline followed by colloid loading. Hypotension (systolic blood pressure [SBP] reduction >20% baseline value or SBP <90 mm Hg) was treated with boluses of phenylephrine or ephedrine according to maternal heart rate. The primary outcome was umbilical arterial blood pH and the secondary outcomes included maternal SBP within 15 minutes after induction of anesthesia, the amount of vasoactive drug administered before end of the surgery, and the incidence of hypotension during cesarean delivery.

RESULTS:
Seventy-five patients were included. After testing by analysis of variance, there was no significant difference in the umbilical arterial pH among the 3 groups (supine group: 7.31 ± 0.03 vs 15° group: 7.30 ± 0.04 vs 30° group: 7.31 ± 0.02, P = .28). The 30° group required significantly less phenylephrine (P = .007) and ephedrine (P = .005) before the end of surgery than the supine group; however, the only benefit observed in the 15° group was that the mean SBP at 3 minutes after spinal injection was significantly improved compared with the supine group.

CONCLUSIONS:
Compared with the supine position, the 30° left-tilt position during surgical preparation did not significantly improve the fetal acid-base status, but it significantly reduced the use of phenylephrine and ephedrine and reduced the incidence of hypotension; however, these benefits were not observed in the 15° left-tilt group.
A concept analysis of ‘trial recruitment’ using the hybrid model – Phase 1 findings
Authors: Delaney Hannah , Devane Declan , Hunter Andrew , Treweek Shaun , Mills Nicola , Gamble Carrol , Smith Valerie 
Published: December 2020

Background: The International Committee of Medical Journal Editors (ICMJE) requires trials submitted for publication to be registered before enrolment of the first participant; however, there is ambiguity around the definition of recruitment and in anchoring the trial start date, end date, recruitment and enrolment, temporally to trial processes. There is potential for variation in how recruitment is reported and understood in trial protocols and trial reports. We report on Phase 1 of a concept analysis of ‘trial recruitment’ and develop a preliminary operational definition of ‘trial recruitment’. Methods: A concept analysis using the hybrid model. We searched randomised and non-randomised trial reports published between January 2018 and June 2019. Included studies were sourced from the five top journals in the category of medicine with the highest impact factor. We examined how recruitment was defined temporally to four time points; screening, consent, randomisation, and allocation. Results: Of the 150 trial reports analysed, over half did not identify a clear time point of when recruitment took place in relation to any of screening/consent/randomisation/allocation. The majority of the assessed trials provided a time frame in relation to the trial (i.e. start/end date), the process that this time frame referred to differed between studies. There was variation across studies in the terminology used to describe entry to the trial and often multiple terms were used interchangeably. Conclusion: There is ambiguity around temporal descriptions of ‘trial recruitment’ in health care journals. Informed by the findings of Phase 1, we developed a preliminary temporal operational definition of trial recruitment based on i) trial recruitment of an individual or cluster and ii) the trial recruitment period. In Phase 2 this definition will be discussed in focus groups with healthcare workers involved in designing/implementing/reporting on trials; to contribute to the final phase (analytical phase) of this concept analysis.
All-normal-dispersion dissipative soliton fiber laser using an offset-splicing graded-index-multimode-fiber-based saturable absorber
Authors: Pan Wei , Jin Liang , Wang Jiazhu , Wang Renyan , Zhang He , Yingtian Xu , Zhao Xin , Li Yang , Ma Xiaohui 
Published: December 2020

All-normal-dispersion (ANDi) dissipative soliton mode-locking is realized based on nonlinear multimode interference (NMI), which is implemented by offset-splicing three pieces of graded-index multimode fibers (GIMFs) and acts as a saturable absorber. The higher-order modes can be excited by offset-splicing GIMFs (OS-GIMFs), which eliminates adding the step multimode fiber (SIMF) into the resonant cavity and the precise length requirement of the SIMF. In the experiment, the stable dissipative soliton mode-locking at 1030 nm can be obtained with the pulse width of 7.3 ps and the repetition rate of 20.52 MHz, and the bandwidth is 6.98 nm. The maximum output is 3.2 mW with the pump power of 257 mW. The OS-GIMFs can significantly improve the saturated absorption and can easily realize dissipative soliton mode-locking in ANDi regions, which makes it attractive in ultrafast photonics.