bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maternal BMI at the time of birth and selected risk factors associated with severe neonatal outcomes: a secondary analysis of the WHO Better Outcomes in Labour Difficulty (BOLD) project
Authors: Pileggi Vicky N. , Oladapo Olufemi T. , Cavenague de Souza Hayala Cristina , Castro Cynthia P. , Abraham Alabi O. , Akintan Adesina L. , Idris Hadiza A. , Oyeneyin Lawal O. , Souza João P. , Camelo José S. 
Published: June 2020

AbstractThe main objective of this secondary analysis was to describe the nutritional status of the Better Outcomes in Labour Difficulty (BOLD) project study population and determine possible associations between maternal nutritional status (as reflected by maternal BMI at the time of birth) and severe neonatal outcomes (SNO). We also analysed previous and index maternal pathologies to determine associations with neonatal outcomes. We used the classification designed by Atalah for maternal BMI and compared with the Hyperglycaemia and Adverse Pregnancy Outcome study one. To describe the nutritional status of this population, figures of distribution and test of normality related to weight and BMI were presented for the women and their babies. To explore the association between maternal BMI data and SNO, theχ2test was performed. To identify a maternal characteristic or a group of characteristics that could predict SNO, we used Fisher’s exact test using previous maternal pathology collected in the BOLD project as well as that in the index pregnancy. In this study, BMI at the time of birth was not associated with neonatal near miss or death. We found that previous maternal obesity, diabetes and chronic hypertension were associated with SNO. Maternal pathology in the index pregnancy such as other obstetric haemorrhage, pre-eclampsia, anaemia and gestational diabetes was associated with SNO.
Dried fruit consumption and cardiometabolic health: a randomised crossover trial
Authors: Sullivan Valerie K. , Petersen Kristina S. , Kris-Etherton Penny M. 
Published: June 2020

AbstractFruit intake is associated with lower risk of cardiometabolic diseases. However, effects of dried fruits on cardiometabolic health are not well researched. We investigated the effect of daily dried fruit consumption compared with a carbohydrate-rich snack on cardiometabolic disease risk factors in adults with increased cardiometabolic risk. A two-period randomised crossover trial was conducted in adults (n 55) with elevated BMI and at least one additional risk factor for cardiometabolic disease to compare the effects of consuming 3/4 cup/d mixed dried fruits (plums, figs, dates and raisins) or an energy- and carbohydrate-matched control snack for 4 weeks. The primary outcome was LDL-cholesterol; secondary outcomes included other lipids and lipoproteins, glucose and insulin, C-reactive protein, blood pressure and vascular stiffness. Linear mixed models were used for data analysis. Lipid and lipoprotein concentrations did not differ between conditions; however, dried fruit increased LDL-cholesterol (0·10 mmol/l, 95 % CI 0·01, 0·20) compared with baseline. Compared with the control, dried fruit increased mean fasting glucose (0·08 mmol/l, 95 % CI 0·005, 0·16; P = 0·038). Vascular outcomes, fasting insulin and C-reactive protein did not differ between conditions. Mean weight changes did not differ (P = 0·55) but tended to increase after both conditions (dried fruit 0·3 kg, 95 % CI –0·09, 0·65; control 0·4 kg, 95 % CI 0·01, 0·75). Thus, short-term daily consumption of a large portion of mixed dried plums, figs, dates and raisins, without structured dietary guidance, did not improve cardiometabolic risk factors, compared with carbohydrate-rich snacks, in adults with increased baseline cardiometabolic risk.
Where does implementation lie? Assessing the determinants of delegation and discretion in post-Maastricht European Union
Authors: Migliorati Marta 
Published: June 2020

AbstractDrawing on a principal–agent framework the article analyses the European Union (EU) politics of delegation in the post-Maastricht era. By means of statistical analysis, it tests the impact of several variables upon the selection of national and supranational agents, as well as on the discretion they enjoy, on the basis of a recently collected data set of EU laws. Findings reveal that pooling and policy complexity favour the involvement of supranational actors in the implementation of EU laws. Moreover, the degree of supranational integration of a policy affects the likelihood of choosing supranational implementers. On the one hand, the Commission enjoys higher discretion vis-à-vis national actors when qualified majority voting applies, and when higher levels of conflict in the Council of Ministers is present. On the other, conflict between the European Parliament and the Council under codecision seems associated with lower supranational discretion, although the result needs further corroboration.
THE ASPECT HYPOTHESIS AND THE ACQUISITION OF L2 PAST MORPHOLOGY IN THE LAST 20 YEARS
Authors: Bardovi-Harlig Kathleen , Comajoan-Colomé Llorenç 
Published: June 2020

AbstractTwenty years ago, a state-of-the-art review inSSLAmarked the coming of age of the study of temporality in second language acquisition. This was followed by three monographs on tense and aspect the next year. This article presents a state-of-the-scholarship review of the last 20 years of research addressing the aspect hypothesis (AH) (Andersen, 1991, 2002; Andersen & Shirai, 1994, 1996), the most tested hypothesis in L2 temporality research. The first section of the article gives an overview of the AH and examines its central tenets, and then explores the results of empirical studies that test the hypothesis. The second section considers studies that have investigated four crucial variables in the acquisition of temporality and the testing of the AH. The third section discusses theoretically motivated areas of future research within the framework of the hypothesis.
A case of AndraStent® fracture in a patient with aortic coarctation: a review of the literature
Authors: Cabrelle Giulio , Milanesi Ornella , Castaldi Biagio 
Published: June 2020

AbstractPercutaneous treatment of aortic coarctation is based on angioplasty and/or stenting of the isthmus. We report a case of a 28-year-old girl suffering from aortic coarctation syndrome (coarctation + ventricular septal defect + bicuspid aorta). She underwent coarctectomy with subclavian flap and pulmonary bandage followed by ventricular septal defect closure and bandage removal in her first year of life. When she was 27 years old, a follow-up echocardiography detected an isthmic pressure gradient and a demodulated Doppler in abdominal aorta. A cardiac catheterisation confirmed the diagnosis of aortic re-coarctation. An AndraStent® XL 48 mm was implanted with a resolution of the isthmic gradient. One year later, because of the reappearance of demodulated Doppler in abdominal aorta, a chest X-ray was performed, which showed a stent third-grade fracture. The fracture was corrected by positioning a covered stent cheatham platinum 45 mm through the fragments. The rarest complication after stenting procedures is the fracture of the device with an incidence between 0.01% and 0.08%. Pressure overload beyond the elastic threshold of the material and the pulsatile tension exerted by the blood flow on the walls of the stent are the main mechanisms at the base of the fracture, together with the compliance of the tissue. A vessel that underwent multiple surgical rearrangements could interfere with and complicate the physiopathology at the basis of the fracture. In conclusion, stenting is a safe technique to treat aortic coarctation; stent fracture is a rare event, and different anatomical and haemodynamic factors are related to this complication.
RYR2 p.R169L mutation and left ventricular hypertrophy in a child with emotion-triggered sudden death
Authors: Kohli Utkarsh , Kuntz Lisa , Nayak Hemal M. 
Published: June 2020

AbstractCatecholaminergic polymorphic ventricular tachycardia is a rare (prevalence: 1/10,000) channelopathy characterised by exercise-induced or emotion-triggered ventricular arrhythmias. There is an overall paucity of genotype-phenotype correlation studies in patients with catecholaminergic polymorphic ventricular tachycardia, and in vitro and in vivo effects of individual mutations have not been well characterised. We report an 8-year-old child who carried a mutation in the coding exon 8 of RYR2 (p.R169L) and presented with emotion-triggered sudden cardiac death. He was also found to have left ventricular hypertrophy, a combination which has not been reported before. We discuss the association between genetic variation in RYR2, particularly mutations causing replacement of arginine at position 169 of RYR2 and structural cardiac abnormalities.
Impact of transport on arrival status and outcomes in newborns with heart disease: a low–middle-income country perspective
Authors: Karmegaraj Balaganesh , Kappanayil Mahesh , Sudhakar Abish , Kumar Raman Krishna 
Published: June 2020

AbstractObjectives:We sought to systematically study determinants of “clinical status at arrival after transport” of neonates with CHD and its impact on clinical outcomes in a low- and middle-income country environment.Methods and results:Consecutive neonates with CHD (n = 138) transported (median distance 138 km; 5–425 km) to a paediatric cardiac programme in Southern India were studied prospectively. Among 138 neonatal transports, 134 were in ambulances. Four neonates were transported by family in private vehicles; 60% with duct-dependent circulation (n = 57) were transported without prostaglandin E1. Clinical status at arrival after transport was assessed using California modification of TRIPS Score (Ca-TRIPS), evidence of end-organ injury and metabolic insult.Upon arrival, 42% had end-organ injury, 24% had metabolic insult and 36% had Ca-TRIPS Score >25. Prior to surgery or catheter intervention, prolonged ICU stay (>48 hours), prolonged ventilation (>48 hours), blood stream sepsis, and death occurred in 48, 15, 19, and 3.6%, respectively. Ca-TRIPS Score >25 was significantly associated with mortality (p = 0.005), sepsis (p = 0.035), and prolonged ventilation (p < 0.001); end-organ injury with prolonged ICU stay (p = 0.031) and ventilation (p = 0.045); metabolic insult with mortality (p = 0.012) and sepsis (p = 0.015).Fifteen babies needed only medical management, 10 received comfort care (due to severe end-organ injury in 3), 107 underwent cardiac surgery (n = 83) or catheter intervention (n = 24), with a mortality of 6.5%. Clinical status at arrival after transport did not impact post-procedure outcomes.Conclusion:Neonates with CHD often arrive in suboptimal status after transport in low- and middle-income countries resulting in adverse clinical outcomes. Robust transport systems need to be integrated in plans to develop newborn heart surgery in low- and middle-income countries.
Natural disasters and child health
Authors: Thamarapani Dhanushka 
Published: June 2020

AbstractWith the increasing number of natural disasters, understanding the links between these events and child health has become timely and pertinent. Using a panel dataset, this paper empirically investigates the persistent effects on child health due to exposure to a series of natural disasters that occurred from 2002 to 2007 in Indonesia. We find that girls exposed to multiple disaster events are 0.19 standard deviations shorter and are 7 per cent more likely to be stunted when measured 7 to 12 years later. We find no persistent effect on boys. From a public policy perspective, we highlight the need for coping strategies beyond access to credit or remittances in order to mitigate growth retardation in children.
Role of different nutrient profiling models in identifying targeted foods for front-of-package food labelling in Brazil
Authors: Duran Ana Clara , Ricardo Camila Zancheta , Mais Laís Amaral , Bortoletto Martins Ana Paula 
Published: June 2020

AbstractObjective:To compare the degree of strictness and agreement of different nutrient profiling models (NPM) used to identify which foods would be required to show front-of-package (FOP) warning labels.Design:Using data of 11 434 packaged foods found in the five largest food retailers in Brazil, we used two published NPM: the Pan American Health Organization (PAHO) model and the NPM used in the Chilean nutritional FOP labelling policy, and compared them with a NPM proposed by the Brazilian National Health Surveillance Agency (Anvisa). The proportion of foods that would be required to show FOP warning labels was calculated overall and by food category. We also tested whether a modified version of the PAHO NPM would behave similarly to the original version.Setting:Brazil.Results:Two-thirds of the packaged products (62 %) would receive FOP warning labels under the PAHO NPM, as compared with 45 % of products using the proposed Anvisa NPM and 41 % if the Chilean NPM was applied. The PAHO NPM identified more foods high in critical nutrients such as sweetened dairy and non-dairy beverages, canned vegetables and convenience foods. Overall agreement between models was considered good with kappa coefficient ranging from 0·57 to 0·92 but was lower for some food categories.Conclusions:We found variations in the degree of strictness and agreement between assessed NPM. The PAHO NPM identified more foods and beverages high in sugar which are among the top contributors to sugar and energy intake in Brazil.
Associations between taste preferences and chronic diseases: a population-based exploratory study in China
Authors: Li Hanqi , Jia Peng , Fei Teng 
Published: June 2020

Abstract

Objective:
To explore the associations between dietary tastes and chronic diseases quantitatively.

Design:
We used the Geodetector method to establish associations between seven tastes and a variety of chronic diseases from the perspective of spatial stratified heterogeneity and explained the effects of dietary tastes on the spatial distribution of chronic diseases.

Setting:
We used crowdsourcing online recipe data to extract multiple taste information about cuisines, combined with point of interest data on categorised restaurant data in different regions, to quantitatively analyse the taste preferences of people in different regions.

Participants:
Crowdsourcing online recipe data and restaurant data in different regions.

Results:
The results showed that sixteen diseases were significantly associated with dietary tastes among the seventy-one types of chronic diseases. Compared with the effects of individual tastes, the interactions of tastes increased the risk of sixteen diseases, and many combinations of tastes produced nonlinear enhancement effects on the risk for diseases.

Conclusions:
This study presents a quantitative study approach based on the crowdsourcing of data to explore potential health risk factors, which can be applied to the exploratory analysis of disease aetiology and help public health authorities to develop corresponding interventions.
An institutional review: dosimetry comparison between simultaneous integrated boost IMRT and VMAT for prostate cancer
Authors: Mukhtar Raheel , Butt Sumera , Rafaye Muhammad Abdur , Iqbal Khalid , Mazhar Sana , Sadaf Tabinda 
Published: June 2020

AbstractPurpose:A comparative study was performed about the plan parameters and quality indices between volumetric arc therapy (VMAT) and intensity-modulated radiotherapy (IMRT) for the treatment of high-risk prostate cancer patients. The aim of this retrospective study was to compare the two methods of external beam radiotherapy IMRT and VMAT in terms of plan quality and efficacy.Material and method:Fifteen high-risk prostate patients were planned for radiotherapy using 6 MV photon. Three dose levels were contoured having Planning Tumour Volume 1 (PTV1 = 48 Gy), Planning Tumour Volume 2 (PTV2 = 57.6 Gy) and Planning Tumour Volume 3 (PTV3 = 60 Gy). Setup margins were given using the CHIP trial method. The prescribed PTV3 dose was 60 Gy in 20 fractions which is biologically equivalent to 74 Gy in 37 fractions using α/β = 3. In case of IMRT, seven fixed beam angles 30, 60, 105, 180, 255, 300 and 330 were used and the dose was optimised using the sliding window method. In case of rapid arc technique, one or two full arcs were used for dose optimisation while keeping all the dose constraints and other planning parameters same used in IMRT. The plan evaluation parameters and Organ at risks (OARs) doses were calculated using a dose volume histogram (DVH).Results:The average D2, D5, D95 and PTVmean for PTV3 were 61.22, 61.13, 58.12, 60.00 Gy and 62.41 62.24 59.53 61.12 Gy for IMRT and VMAT, respectively. The averages V60 for bladder and V30 for rectum were 22.81, 25 and 67, 65% for IMRT and VMAT, respectively. The average homogeneity index (HI), conformity index (CI) and gradient index (GI) were 1.04, 1.4833, 14.79 and 1.04, 1.704, 7.89 for IMRT and VMAT, respectively.Conclusion:VMAT takes less dose-delivery time and lesser number of monitoring units than IMRT, thus it compensates the intrafractional movements during dose delivery. The Dose GI in VMAT was much better than IMRT. This indicates sharper dose fall off near the normal tissue. No other major differences were observed in terms of plan evaluation parameters between IMRT and VMAT techniques. So, we conclude that VMAT technique is more efficient than IMRT in terms of plan quality and dose delivery.
Omission-Based Abstraction for Answer Set Programs
Authors: SARIBATUR ZEYNEP G. , EITER THOMAS 
Published: June 2020

AbstractAbstraction is a well-known approach to simplify a complex problem by over-approximating it with a deliberate loss of information. It was not considered so far in Answer Set Programming (ASP), a convenient tool for problem solving. We introduce a method to automatically abstract ASP programs that preserves their structure by reducing the vocabulary while ensuring an over-approximation (i.e., each original answer set maps to some abstract answer set). This allows for generating partial answer set candidates that can help with approximation of reasoning. Computing the abstract answer sets is intuitively easier due to a smaller search space, at the cost of encountering spurious answer sets. Faithful (non-spurious) abstractions may be used to represent projected answer sets and to guide solvers in answer set construction. For dealing with spurious answer sets, we employ an ASP debugging approach to help with abstraction refinement, which determines atoms as badly omitted and adds them back in the abstraction. As a show case, we apply abstraction to explain unsatisfiability of ASP programs in terms of blocker sets, which are the sets of atoms such that abstraction to them preserves unsatisfiability. Their usefulness is demonstrated by experimental results.
Effect of dicamba rate and application parameters on protoporphyrinogen oxidase inhibitor-resistant and -susceptible Palmer amaranth (Amaranthus palmeri) control
Authors: Coffman Wyatt , Barber Tom , Norsworthy Jason K. , Kruger Greg R. 
Published: June 2020

AbstractThroughout eastern Arkansas, Palmer amaranth resistant to protoporphyrinogen oxidase (PPO)-inhibiting herbicides (Group 14 herbicides) has become widespread. Most PPO-resistant Palmer amaranth biotypes possess a target-site mutation, but a metabolic resistance mechanism to fomesafen (Group 14) has also been identified. Once metabolic resistance manifests, plants may also be tolerant to other herbicides and sites of action. To evaluate whether varying spray parameters affected control of PPO-resistant Palmer amaranth in dicamba-tolerant crops, field trials were conducted in 2017 and 2018 at the Lon Mann Cotton Research Station near Marianna, AR, and on-farm in Marion, AR. The experiment included split plot factors of dicamba rate, nozzle type, and carrier volume, with a whole plot factor of population. Dicamba was applied at 560 or 1120 g ae ha−1 through 110015 TTI or AirMix nozzles at 70 or 140 L ha−1 to PPO-resistant or PPO-susceptible Palmer amaranth. Palmer amaranth control 14 d after treatment (DAT) was influenced by an interaction between population and carrier volume. PPO-resistant Palmer amaranth control 14 DAT was 81% regardless of carrier volume, compared with 90% and 95% control at 70 and 140 L ha−1, respectively, of the PPO-susceptible population. An interaction between nozzle type and carrier volume influenced Palmer amaranth control 21 DAT, whereas AirMix nozzles at 140 L ha−1 controlled Palmer amaranth at a greater level (94%) than any other nozzle and carrier volume combination (≤90%). An interaction between population and dicamba rate influenced the relative density of Palmer amaranth 21 DAT. PPO-resistant Palmer amaranth density was less affected by dicamba at either rate than PPO-susceptible Palmer amaranth, relative to the nontreated check. Results concur with those of other research that suggest PPO-resistant Palmer amaranth is harder to control with dicamba. Otherwise, increasing carrier volume affected overall Palmer amaranth control to a greater degree than any other factor.
The effects of integrating a cereal rye cover crop with herbicides on glyphosate-resistant horseweed (Conyza canadensis) in no-till soybean
Authors: Essman Alyssa I. , Loux Mark M. , Lindsey Alexander J. , Dobbels Anthony F. , Regnier Emilie E. 
Published: June 2020

AbstractCurrent recommendations for the control of glyphosate-resistant horseweed [Conyza canadensis (L.) Cronquist var. canadensis] in soybeans [Glycine max (L.) Merr.] consist of comprehensive herbicide programs, which often include herbicide applications outside the soybean growing season. Integration of cover crops with herbicides could potentially improve C. canadensis control and allow for a reduction in herbicide inputs. Two separate field studies were conducted from 2016 through 2018 with the objectives of: (1) determining the effect of planting date and seeding rate of a cereal rye (Secale cereale L.) cover crop on C. canadensis population density and control in the subsequent soybean crop; and (2) determining whether the cover crop could replace a fall herbicide treatment or allow for a reduction in the use of spring-applied residual herbicides. There was no effect of rye planting date, late September versus late October, on C. canadensis density in either study. In 2016 to 2017, C. canadensis density was greater in the absence of a rye cover crop in both studies, but otherwise not affected by seeding rates of 50 versus 100 kg ha−1. In the 2017 to 2018 season, the presence of rye resulted in an increased C. canadensis density in the spring residual herbicide study (Study I), and had no effect in the fall herbicide study (Study II). Conyza canadensis densities were lowest in the treatments where a comprehensive spring residual or fall herbicide treatment had been applied, averaged over rye planting date and seeding rate. Earlier-planted rye at a higher seeding rate produced the most biomass but did not result in lower C. canadensis densities. These results suggest that cereal rye planted at a density of 50 kg ha−1 as a cover crop before no-till soybeans may be sufficient to reduce glyphosate-resistant C. canadensis plant density, but cannot be relied upon to reduce the need for fall herbicide treatments and spring residual programs.