bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recovery and resiliency of skin microbial communities on the southern leopard frog (Lithobates sphenocephalus) following two biotic disturbances
Authors: Weeks Denita M. , Parris Matthew J. , Brown Shawn P. 
Published: September 2020

Abstract
Background
Microorganisms have intimate functional relationships with invertebrate and vertebrate taxa, with the potential to drastically impact health outcomes. Perturbations that affect microbial communities residing on animals can lead to dysbiosis, a change in the functional relationship, often associated with disease. Batrachochytrium dendrobatidis (Bd), a fungal pathogen of amphibians, has been responsible for catastrophic amphibian population declines around the globe. Amphibians harbor a diverse cutaneous microbiome, including some members which are known to be antagonistic to Bd (anti-Bd). Anti-Bd microorganisms facilitate the ability of some frog populations to persist in the presence of Bd, where other populations that lack anti-Bd microorganisms have declined. Research suggests disease-antagonistic properties of the microbiome may be a function of microbial community interactions, rather than individual bacterial species. Conservation efforts have identified amphibian-associated bacteria that exhibit anti-fungal properties for use as ‘probiotics’ on susceptible amphibian populations. Probiotic application, usually with a single bacterial species, may benefit from a greater understanding of amphibian species-specific microbiome responses to disturbances (e.g. dysbiosis vs. recovery). We assessed microbiome responses to two microbial disturbance events over multiple time points.

Results
Exposing Lithobates sphenocephalus (southern leopard frog) adults to the biopesticidal bacteria Bacillus thuringiensis, followed by exposure to the fungal pathogen Bd, did not have long term impacts on the microbiome. After initial shifts, microbial communities recovered and returned to a state that resembled pre-disturbance.

Conclusions
Our results indicate microbial communities on L. sphenocephalus are robust and resistant to permanent shifts from some disturbances. This resiliency of microbial communities may explain why L. sphenocephalus is not experiencing the population declines from Bd that impacts many other species. Conservation efforts may benefit from studies outlining amphibian species-specific microbiome responses to disturbances (e.g. dysbiosis vs. recovery). If microbial communities on a threatened amphibian species are unlikely to recover following a disturbance, additional measures may be implemented to ameliorate the impacts of physical and chemical stressors on host-associated microbial communities.
Protective effects of Curcuma longa rhizomes ethyl acetate extract against alcohol induced oxidative stress and nephrotoxicity in female Wistar rats
Authors: Eteng Ofem , C.A. MOSES  , J. ENOBONG  , A.J. AKAMO  , D.I. AKINLOYE  , R.N. UGBAJA  , O.A. AKINLOYE  
Published: September 2020

Abstract. Eteng OE, Moses CA, Enobong J, Akamo AJ, Akinloye DI, Ugbaja RN, Akinloye OA. 2020. Protective effects of Curcuma longa rhizomes ethyl acetate extract against alcohol induced oxidative stress and nephrotoxicity in female Wistar rats. Biofarmasi J Nat Prod Biochem 21: 5-12. This study aimed to evaluate the protective effect of Curcuma longa Linn. (syn. Curcuma domestica Val.) rhizomes ethyl acetate extract (CLREAE) facing alcohol-induced oxidative stress and nephrotoxicity. Thirty female (30) Wistar rats were categorized randomly into six groups. Groups 1, 2, 3, 4, 5 and 6 were treated with normal saline; 20% ethanol; 100 mg of CLREAE + 20% ethanol; 200 mg of CLREAE + 20%; 350 mg of CLREAE + 20% ethanol and 350 mg of CLREAE respectively for 14 days. A significant (p<0.05) decrease in the SOD, CAT and GPx activities and GSH concentration of rat treated with only 20% ethanol were found when compared to the normal control group, whereas a significant (P<0.05) increase in the groups pretreated with different doses of the CLREAE were also found when compared to groups with only 20% ethanol treatment. Thus, comparing to the normal control group, treatment with the CLREAE fetched a significant (p<0.05) decrease in the renal biomarkers (creatinine and urea). Whilst, comparing to the groups with 20% methanol treatment, a significant (p<0.05) increase happened in the groups pretreated with different doses of the CLREAE. There was a significant (p<0.05) decrease on Kidney MDA level in rats pretreated with different doses of CLREAE compared with the normal control. It was shown in the results of the histology that there was a physiologic recovery in the kidney tissues as groups were treated with different doses of the CLREAE. Evidenced by reduced necrosis of tubular and glomerular epithelial, the signs of protection against toxicity were found on the rats. The study suggested that through in vivo free radical scavenging ability, the CLREAE has protective effects against alcohol-induced oxidative stress and nephrotoxicity in female Wistar rats.
Clinical features of ankylosing spondylitis in patients with secondary AA amyloidosis
Authors: Rumyantseva D. G. , Agafonova E. M. , Krasnenko S. O. , Starkova A. S. , Urumova M. M. , Erdes Sh. 
Published: September 2020

Renal AA amyloidosis is the most severe type of renal pathology in patients with ankylosing spondylitis (AS). The characteristic symptoms of AA amyloidosis in rheumatic diseases do not often occur for years, making it difficult to diagnose it early and to start adequate therapy.Objective: to identify the clinical features of AS complicated by secondary AA amyloidosis.Patients and methods. The investigation enrolled 9 patients with AS (according to the 1984 modified New York criteria) and histologically confirmed secondary AA amyloidosis (Group 1). A comparison group included 216 AS patients without amyloidosis (Group 2).Results and discussion. In Group 1 patients, the age at the onset of AS was significantly less and the disease duration was 4 times longer than those in Group 2. All the patients with AA amyloidosis had enthesitis and arthritis, including those of the hip joints. The scores of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Ankylosing Spondylitis Disease Activity Score with C-reactive protein (ASDAS-CRP), and the acute phase inflammation index CRP were higher in Group 1 than in Group 2.Conclusion. The clinical feature of AS complicated by secondary AA-amyloidosis is the long duration of the disease and the high frequency of juvenile onset, non-axial manifestations (arthritis, coxitis and enteritis), as well as the high activity of systemic inflammation.
Hubungan Kompensasi, Motivasi dan Kepuasan Kerja dengan Kinerja Dokter Pada BLUD Rumah Sakit Umum Daerah Dr. Loekmono Hadi Kudus
Authors: Sudarmono Sudarmono , Margawati Ani , Jati Sutopo Patria 
Published: September 2020

Sejak pelaksanaan Jaminan Kesehatan Nasional (JKN) beberapa dokter di Rumah sakit mengalami penurunan pendapatan, akibatnya timbul ketidakpuasan dan turunnya motivasi sehingga berakibat pada menurunnya kinerja dokter yang dimanifestasikan berupa pembatasan jumlah kunjungan pasien, pengalihan pasien dari RS ke praktek pribadi atau ke rumah sakit lainnya dan manifestasi penurunan kinerja lainnya. Tujuan penelitian ini untuk menganalisis hubungan antara kompensasi, motivasi dan kepuasan kerja dengan kinerja dokter pada BLUD RS dr. Loekmono Hadi Kudus. Penelitian ini menggunakan metode kuantitaif dengan pendekatan cross sectional. Sumber data dalam penelitian dibagi menjadi dua yaitu sumber data primer dan data sekunder. Jumlah sampel pada penelitian ini sebanyak 49 orang.Analisa penelitian ini menggunakan analisa univariat didapatkan hasil variabel kompensasi kategori tinggi sebesar 53.1 %, variabel kepuasan kerja sebesar 51,0% dan variabel motivasi kerja sebesar 53,1%. Sedangkan hasil analisa bivariate didapatkan hasil bahwa variabel kompensasi, kepuasan kerja, dan motivasi memiliki nilai p value kurang dari 0,05 yang menunjukkan ketiga variabel tersebut berhubungan dengan kinerja dokter dan memiliki p value kurang dari 0,25, sehingga dapat dilanjutkan ke analisa multivariat. Sedangkan hasil uji multivariate dengan menggunakan uji regresi logistik didapatkan pada variabel motivasi kerja didapatkan hasil p value =0.000 dengan Exp(B) = 8,155.Kesimpulan penelitian ini adalah motivasi dokter memiliki pengaruh 8,155 kali lebih baik dibandingkan dengan variabel independen lainnya.Penelitian ini merekomendasikan agar pihak manajemen RS memperhatikan sistem pengembangan karir dan promosi, meningkatkan komunikasi interpersonal, memberikan reward pada dokter dan memberikan tanggung jawab sesuai tugas dan kewenangan dokter untuk dapat meningkatkan kepuasan kerja dokter.
Sistem Pemantauan Pengobatan Pasien TB Paru di Puskesmas Kabupaten Kudus
Authors: Setiawan Ari , Jati Sutopo Patria , Agushybana Farid 
Published: September 2020

Pecatatan pengobatan Pasien TB paru tentang jadwal pengobatan pasien TB Paru di puskemas Kabupaten Kudus pada lembar catatan pengobatan. Dimana ada lembar yang disimpan petugas dan ada lembar yang dibawa oleh pasien. selain itu, dalam mengirimkan pean petugas harus mencari kontak pasien melihat catatan pasien yang diimpan dalam box file. Dari kondisi tersebut menyebabkan petugas mengalami kendala dalam memantau pasien dalam jadwal pengobatan. Tujuan penelitian ini untuk menghasilkan Sistem Informasi pemantauan pengobatan pasien TB Paru yang dapat digunakan untuk memantau pengobatan pasien, pengiriman pesan pengingat dan menghasilkan rekap laporan mendukung evaluasi Program TB Paru di Kabupaten Kudus. Jenis penelitian yang digunakan adalah actions research berupa pengembangan sistem (system development). Pengembangan sistem menggunakan metode FAST (Framework for the Application of System Techniques). Subjek penelitian terdiri dari 5 responden yang terdiri dari kepala seksi penanggulanagan penyakit menular, pengelola TB Paru di Dinas Kesehatan dan 3 orang petugas TB Paru Puskemas. Hasil dari pengembangan ini adalah sitem informasi berbasis web dengan fitur SMS gateway. Dengan sistem ini petugas lebih mudah dalam memantau pengobatan pasien. dalam list pasien dapat dilihat jadwal pengobatan berdasarkan tanggal yang di inginkan oleh petugas. Dalam pengiriman pesan pengingat lebih mudah dilakukan karena nomor handphone pasien tersimpan dalam basis data sistem. Selain itu rekap laporan pengobatan pasien TB Paru, dan grafik pengobatan pasien berdasarkan puskesmas.
Analysis of Linen Management in Inpatient Room of X Hospital of Semarang City
Authors: Nurmandhani Ririn 
Published: September 2020

Laundry unit is a non-medical support unit that provides linen services, especially for inpatient room. Based on the result from preliminary study, it is found that disarragement of linen management in Inpatient Room of X hospital Kota Semarang occured, which affected a logistic input, implementation, and logistic output. Analysis of linen management in inpatient room X Hospital Semarang is mandatory.The research design was qualitative with cross sectional approach. The main informants in this research were 4 laundry officers, Head of CSSD and Laundry, 2 nurses, 2 nurse assistants, and Head of Nursing Division. The triangulation informants were 1 Head and 1 staff of RT and IPS RS. Data were collected by in-depth interview and observation techniques.The results of research showed that human resources factor in laundry management was lacking, the infrastructure was available but was not working properly. Guidelines and SPOs were available but the used of PPE was lacking. Linen planning had not run well. In the execution was not been running properly because linen maintenance, recording and reporting was not in accordance with the should, the linen identification and inventory control was not run well. Linen output still contained stain spots of 10%, thin fabric fiber of 5%, and there is still a delay of linen availability of 5% because the number of linen was not up to standart.Sugesstion for management was to increase the number and capability of human resources, the maintenance of infrastructure to increase the value of use, and good planning for the lack of linen can be fulfilled and done the sorting so that the linen that had stain spots not circulating anymore in the room.
Development of Administration Information System Using Web-Based Vaccine to Support Immunization Management at West Aceh District Health Office
Authors: Jihad Fikri Faidul , Sediyono Eko , Nurjazuli Nurjazuli 
Published: September 2020

Universitas DiponegoroFakultas Kesehatan MasyarakatProgram Studi Magister Ilmu Kesehatan MasyarakatKonsentrasi Sistem Informasi Manajemen Kesehatan2017 ABSTRAK Fikri Faidul JihadPengembangan Sistem Informasi Administrasi Penggunaan Vaksin Berbasis Web untuk Mendukung Pengelolaan Imunisasi di Dinas Kesehatan Kabupaten Aceh Baratxvii + 137 halaman + 28 tabel + 41 gambar + 15 lampiran Imunisasi terbukti efektif dalam mencegah berbagai penyakit yang dapat dicegah dengan imunisasi (PD3i). Mekanisme penyelenggaraan imunisasi termasuk pengelolaan rantai vaksin, pencatatan dan pelaporan serta supervisi dan bimbingan teknis. Agar pelaksanaan program imunisasi berhasil, maka semua unsur harus berjalan dengan baik, termasuk manajemen penggunaan vaksin yang bertujuan terhadap peningkatan pengelolaan administrasi vaksin imunisasi. Tujuan dari penelitian ini adalah untuk mengembangkan sistem informasi administrasi penggunaan vaksin untuk mendukung pengelolaan imunisasi di Dinas Kesehatan Kabupaten Aceh Barat.Jenis penelitian yang digunakan merupakan Pra-Eksperimental Design (One-Group Pretest-Postest Design). Pengembangan sistem menggunakan metode FAST (Framework for the Application of System Techniques). Subjek penelitian terdiri dari 7 responden untuk Analisa kebutuhan pengembangan sistem informasi dan 15 responden untuk uji coba sistem informasi. Hasil Analisis data secara deskriptif menunjukkan bahwa nlai rerata tertimbang secara keseluruhan kualitas informasi sebelum pengembangan sistem sebesar 2,27 dan setelah pengembangan sistem 3,36. Terdapat peningkatan nilai rerata sesudah pengembangan sistem sebesar 1,09 artinya terdapat perbedaan kelengkapan, kemudahan, kesesuaian, keakuratan, ketepatan waktu sebelum dan sesudah pengembangan sistem.Perlu adanya dukungan dan komitmen dari Dinas Kesehatan Kabupaten Aceh Barat untuk memanfaatkan sistem informasi ini sebagai sumber informasi untuk mendukung pengelolaan administrasi vaksin imunisasi di Dinas Kesehatan Kabupaten Aceh Barat. Kata kunci : Sistem Informasi, administrasi vaksin, Dinas Kesehatan Kabupaten Aceh BaratKepustakaan : 42 (2001-2015)
Karakteristik Third Place dan Tipologi Kafe di Yogyakarta Kasus: Kawasan Karangwuni dan Sekitarnya
Authors: Sireki Talenta Nanda , Wibisono Bambang Hari 
Published: September 2020

Technology advancements tend to trigger the transformation of the characteristics of third place, especially in the forms of interactions and activities. This research is aimed to explore the third place characteristics, typology, spatial development, and identify factors that construct the typology of cafés as third place in Karangwuni sub-district and the area nearby (Karangwuni, Karanggayam, Karangasem Baru, Karangbendo, dan Karangmalang). The research method used in this study was a mix-method, with deductive-explorative approach using field observation and questionnaire to the visitor of café as a third place, which were opened during the period between 2016 to 2018, and located in Karangwuni area and the areas nearby. The results of this study shows that the characteristics of cafés in Karangwuni and the areas nearby as a third place are still in accordance with Oldenburg’s characteristics. However, it is also revealed that there have been shifts of the form of interactions and activities within the cafés space. Typology analysis showed that there are several types of cafés that match with the form of co-working space, and there are spatial trends in typology based on activity. Meanwhile, some factors constructing the typology have relation with space settings in determining the behaviors of the users.
Was Hegel an Authoritarian Thinker?Reading Hegel’sPhilosophy of Historyon the Basis of his Metaphysics
Authors: Baumann Charlotte 
Published: September 2020

AbstractWith Hegel’s metaphysics attracting renewed attention, it is time to address a long-standing criticism: Scholars from Marx to Popper and Habermas have worried that Hegel’s metaphysics has anti-individualist and authoritarian implications, which are particularly pronounced in hisPhilosophy of History, since Hegel identifies historical progress with reason imposing itself on individuals. Rather than proposing an alternative non-metaphysical conception of reason, as Pippin or Brandom have done, this article argues that critics are broadly right in their metaphysical reading of Hegel’s central concepts. However, they are mistaken about what Hegel’s approach entails, when one examines the specific types of states discussed (and rejected) by the philosopher in hisPhilosophy of History. Even on a traditional metaphysical reading, Hegel is not only non-authoritarian; he also makes a powerful argument concerning freedom, whereupon the freest society involves collective oversight and the shaping of social structures so as to ensure that they benefit everybody.
Electromagnetic-launch-based method for cost-efficient space debris removal
Authors: Hou Chongyuan , Yang Yuan , Yang Yikang , Yang Kaizhong , Zhang Xiao , Lu Junyong 
Published: September 2020

Abstract
The increase in space debris orbiting Earth is a critical problem for future space missions. Space debris removal has thus become an area of interest, and significant research progress is being made in this field. However, the exorbitant cost of space debris removal missions is a major concern for commercial space companies. We therefore propose the debris removal using electromagnetic launcher (DREL) system, a ground-based electromagnetic launch system (railgun), for space debris removal missions. The DREL system has three components: a ground-based electromagnetic launcher (GEML), suborbital vehicle (SOV), and mass of micrometer-scale dust (MSD) particles. The average cost of removing a piece of low-earth orbit space debris using DREL was found to be approximately USD 160,000. The DREL method is thus shown to be economical; the total cost to remove more than 2,000 pieces of debris in a cluster was only approximately USD 400 million, compared to the millions of dollars required to remove just one or two pieces of debris using a conventional space debris removal mission. By using DREL, the cost of entering space is negligible, thereby enabling countries to remove their space debris in an affordable manner.
How Katrina Shaped Trust and Efficacy in New Orleans
Authors: Holman Mirya R. , Lay J. Celeste 
Published: September 2020

Abstract
In 2005, Hurricane Katrina led to substantial demographic changes in New Orleans. The city lost large numbers of its African American population and became more diverse with the arrival of more Latino migrants and more highly educated, affluent white newcomers. Demographic change has the potential to depress political trust, efficacy, and trust in others. In this essay, we show that more than 10 years after Katrina, neither white nor Black New Orleanians trust local or national government. Black residents, particularly Black women, are generally more distrustful of their neighbors, whites, Latinos, and newcomers in the city. White newcomers are more efficacious and trusting than pre-Katrina white residents. These findings provide more evidence for the thesis that race and place shape trust and that Katrina continues to have an impact on New Orleans in distinctly racialized ways.
Numerical study on the effect of planar normal and Halbach magnet arrays on micromixing
Authors: Bahrami Dariush , Nadooshan Afshin Ahmadi , Bayareh Morteza 
Published: September 2020

Abstract
The effective mixing process is critical in biological and chemical processes. The main objective of the present study is to investigate the influence of normal and Halbach magnet arrays on the mixing performance of a three-inlet micromixer numerically. In this microdevice, ferrofluid is injected into the center inlet, and water is injected into two other inlets. The influence of Remanent Flux Density Norm (RFDN), number of magnets, magnet distance from the main microchannel entrance, and inlet flow rate is considered. It is revealed that the micromixer with magnets exhibits a 165% improvement in the mixing efficiency compared to the one with no magnetic field. The results show that increasing the magnetic field does not always increase the mixing quality. Even in some cases, it has a negative effect. It is demonstrated that the mixing efficiency is strongly influenced by the magnet arrangement. An optimal position is found for the magnet arrangement to achieve the maximum mixing efficiency of 91%. Contrary to the normal configuration, Halbach magnet array creates a parabolic profile for flux density. Halbach array can improve the mixing performance, depending on all magnets’ RFDN. The proposed microchannel can be used as a useful device for biological applications.
Words are constructions, too: A construction-based approach to English ablaut reduplication
Authors: van de Weijer Jeroen , Wei Weiyun , Wang Yumeng , Ren Guangyuan , Ran Yunyun 
Published: September 2020

AbstractIn this article we present a new approach to words of the typezigzag,chitchat, etc. in English. Such words form a formal (phonological) and functional (semantic) pattern in English. We argue that this pattern should be analysed in a construction-based approach, which has clear advantages over other approaches, e.g. analyses involving extragrammaticality or a synchronically productive reduplication process. We propose to extend the construction-based approach beyond its original scope (syntactic constructions) to words that may even no longer be morphologically complex. Finally, we make a tentative suggestion about how the difference between productive and unproductive patterns could be captured in the construction-based approach.
Transnational State Elites and the Neoliberal Project in Mexico
Authors: Salas Porras Alejandra 
Published: September 2020

AbstractThis article explores the connection between the emergence of transnational state elites and the construction of a neoliberal project in Mexico. It argues that transnationalization of Mexican state elites was part of the process that led to the adoption of a neoliberal project since the 1980s and that it entailed an increasingly greater participation in global networks as well as a greater affinity with the standards, practices and norms of transnational organizations and global technocrats. The process was very dynamic, and it unfolded through a set of reforms that gradually, but steadily, transformed the political economy from a state-centered to a market-centered political economy. It launched a group of neoliberal reformers to transnational spaces following a combination of paths that included: (1) interlocking with regional and global corporate networks; (2) participation in regional and global think tanks and policy making bodies; (3) a long and active trajectory in international organizations; and (4) an academic and professional career allowing them to become global experts, acknowledged by the global corporate, financial and technocratic communities as the most qualified and trustworthy negotiators and intermediaries.