bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Guhong injection combined with atorvastatin on angina pectoris of coronary heart disease and its influence on Hemorheology and oxidative stress
Authors: Wang Ze , Du Li , Hu Mengyuan 
Published: January 2021

Objective: To explore the effect of Guhong injection combined with atorvastatin on CHD patients with angina pectoris and its influence on hemorheology and oxidative stress.Methods: 80 CHD patients with angina pectoris admitted to our hospital from December 2018 to December 2019 were randomly divided into the observation group (40 cases) and the control group (40 cases) by use of the random number table. The patients in the control group were treated with atorvastatin, while those in the observation group were treated with Guhong injection on the basis of the control group. The course of treatment was 2 weeks for each group. The treatment effect, the frequency of angina pectoris seizure and its duration before and after treatment, the changes of hemorheology indexes and oxidative stress and the occurrence of adverse reactions were compared between the two groups.Results: the total effective rate of the observation group (92.50%) was higher than that of the control group (70.00%) (p < .05). The frequency of angina pectoris seizure and its duration in these two groups after treatment were lower than those before treatment (Observation group: t = 25.588, 23.009; Control group: t = 16.587, 16.263; p < .05); After treatment, the frequency of angina pectoris seizure and its duration in the observation group were lower than those in the control group (t = 15.191, 9.425; p < .05). In the observation group, the hemorheology indexes after treatment were lower than those before treatment (t = 6.742, 15.224, 6.983, 23.537, p < .05); the hemorheology indexes after treatment in the observation group were lower than those in the control group (t = 5.201, 13.913, 5.539, 13.745; p < .05). In the observation group, the level of serum SOD after treatment was higher than that before treatment, while the levels of LPO and MDA after treatment were lower than those before treatment (t = 10.839, 6.924, 8.466; p < .05); the level of serum SOD after treatment in the observation group was higher than that in the control group, while the levels of LPO and MDA after treatment in the observation group were lower than those in the control group (t = 6.171, 6.432, 5.394; p < .05). The incidence of adverse reactions in the observation group was lower than that in the control group (p < .05).Conclusions: Guhong injection combined with atorvastatin has an obvious clinical effect on CHD patients with angina pectoris, and it can improve hemorheology indexes and oxidative stress reaction with fewer adverse reactions.
A case report on aggressive fibromatosis of the arm and shoulder
Authors: Emile Sameh Hany , Sakr Ahmad 
Published: January 2021

Background: Aggressive fibromatosis is a locally aggressive tumor that originates from the deep musculo-aponeurotic structures. In this report, we describe the case of an adolescent male with painless, progressively growing swelling in his right arm necessitated surgical excision and postoperative pathologic examination revealed aggressive fibromatosis.Case presentation: A 15-year-old boy presented with a painless, progressively growing swelling of his right arm. The swelling was firm, non-tender and with restricted mobility. MRI imaging revealed a well-defined, heterogenous, lobulated swelling extending beneath arm and shoulder muscles. Wide local excision of the swelling was done under general anesthesia and pathologic examination revealed aggressive fibromatosis of the arm. Adjuvant radiotherapy was provided to the patient to reduce the risk of local recurrence of the tumor.Conclusion: Aggressive fibromatosis of the upper limb presents as a painless, progressively growing swelling. Assessment with MRI is imperative for making a preliminary diagnosis. Wide local excision with safety margin with adjuvant radiotherapy is the main line of treatment to minimize the incidence of recurrence and preserve the limb.
Experimental and simulation study of the temperature distribution in a bench‐scale fixed bed Fischer–Tropsch reactor
Authors: Shen Jianqi , Li Yun‐Chao , Ho Wei H. , Liu Xinying , Hildebrandt Diane 
Published: January 2021

AbstractThe temperature distribution in a bench‐scale fixed bed Fischer–Tropsch reactor using Co‐based catalyst was investigated under conditions of 2 MPa and 458 K at various syngas partial pressures and space velocities. The single‐tube reactor had a diameter of 0.05 m, which is representative of the diameters used in industrial applications. With a special designed temperature measurement, the detailed temperature distribution in a bench‐scale reactor was reported for the first time. The changes of maximum temperature in the bed and hot spot region were discussed at different N2 flow rate and gas hourly space velocity. A 2D pseudo‐homogeneous fixed bed reactor model was developed using ANSYS Fluent. A position‐dependent heat‐transfer coefficient, which considered more accurate in temperature prediction, was applied. The model was validated against both the reaction results and the measured temperatures. The inferred properties within the reactor were analyzed to give insight as to how to increase the reactor production capacity.
Transition from periodic to chaotic AC electroosmotic flows near electric double layer
Authors: Hu Zhongyan , Zhao Tianyun , Zhao Wei , Yang Fang , Wang Hongxun , Wang Kaige , Bai Jintao , Wang Guiren 
Published: January 2021

AbstractElectroosmotic flows (EOFs) on insulated interfacial surface commonly exists as interfacial flows. Previously theoretical studies indicate that EOFs of Newtonian fluids on the insulated interfacial surface are steady in microchannels with symmetric zeta potentials (Suresh and Homsy, Physics of Fluids, 2004, 16, 2,349). Restricted by flow diagnostic methods in microfluidics, few velocity measurements of instantaneous EOFs have been reported, and the existence of unsteady EOFs on the insulated surface remains unclear. In this investigation, the velocity fluctuations of EOFs generated under AC electric field (named as ACFEOF) overlapped on a steady pressure‐driven flow are measured by laser induced fluorescence photobleaching anemometer, at the diffuse electric double layer (EDL) on the bottom wall far from electrodes. Chaotic velocity fluctuations according to unsteady ACFEOF has been, for the first time, observed. Stokes number (St) and electrical Reynolds number (ReE) related to oscillation and electro‐inertial effect are suggested to control chaotic ACFEOF.
Population responses to a historic drought across the range of the common monkeyflower (Mimulus guttatus)
Authors: Kooyers Nicholas J. , Morioka Kelsie A. , Colicchio Jack M. , Clark Kaitlyn S. , Donofrio Abigail , Estill Shayne K. , Pascualy Catalina R. , Anderson Ian C. , Hagler Megan , Cho Chloe , Blackman Benjamin K. 
Published: January 2021

PREMISEDue to climate change, more frequent and intense periodic droughts are predicted to increasingly pose major challenges to the persistence of plant populations. When a severe drought occurs over a broad geographical region, independent responses by individual populations provide replicated natural experiments for examining the evolution of drought resistance and the potential for evolutionary rescue.METHODSWe used a resurrection approach to examine trait evolution in populations of the common monkeyflower, Mimulus guttatus, exposed to a record drought in California from 2011 to 2017. Specifically, we compared variation in traits related to drought escape and avoidance from seeds collected from 37 populations pre‐ and post‐drought in a common garden. In a parallel experiment, we evaluated fitness in two populations, one which thrived and one which was nearly extirpated during the drought, under well‐watered and dry‐down conditions.RESULTSWe observed substantial variation among populations in trait evolution. In the subset of populations where phenotypes changed significantly, divergence proceeded along trait correlations with some populations flowering rapidly with less vegetative tissue accumulation and others delaying flowering with greater vegetative tissue accumulation. The degree of trait evolution was only weakly correlated with drought intensity but strongly correlated with initial levels of standing variation. Fitness was higher in the post‐drought than pre‐drought accessions in both treatments for the thriving population, but lower in both treatments for the nearly extirpated population.CONCLUSIONSTogether, our results indicate that evolutionary responses to drought are context dependent and reflect the standing genetic variation and genetic correlations present within populations.
AlCl3‐Saturated Ionic Liquid Anolyte with an Excess of AlCl3 for Al–Graphite Dual‐Ion Batteries
Authors: Wang Shutao , Kovalenko Maksym V. , Kravchyk Kostiantyn V. 
Published: January 2021

AbstractAl–graphite dual‐ion batteries (AGDIBs) represent a compelling battery concept for large‐scale stationary storage of electricity in view of their safety, low cost, long cycling life, and high energy efficiency (80–90 %). However, at present, the deployment of AGDIBs is intrinsically limited by their low cell‐level energy density as a result of the non‐rocking‐chair operation principle and, consequently, the need for large quantities of acidic chloroaluminate ionic liquid (IL) anolytes as a reservoir of Al2Cl7− ions required for AGDIB operation. Thus far, AGDIBs have commonly employed IL anolytes with moderate acidity (AlCl3/Lewis base molar ratio of 1.3), which corresponds to charge‐storage anolyte capacity of ca. 19 mAh g−1, eventually resulting in low cell‐level energy densities of 20–30 Wh kg−1. In this work, we present an AGDIB utilizing an AlCl3‐saturated IL anolyte, containing an excess of AlCl3 powder for maintaining constant acidity during operation, leading to a theoretical capacity of 52 mAh g−1. The resultant AGDIB possesses an energy density of 59.1 Wh kg−1, along with a high energy efficiency of 85 % and an average discharge voltage of 1.71 V.
Consumption on steroids: The effect of testosterone on preferences for conspicuous consumption and the moderating role of intrasexual competition
Authors: Nepomuceno Marcelo Vinhal , Stenstrom Eric 
Published: January 2021

AbstractIn line with recent research suggesting that testosterone may only be related to decisions under specific conditions, we show that testosterone is associated with conspicuous consumption only when intrasexual competition is high. In three studies, we provide empirical evidence that prenatal and circulating testosterone are only related to conspicuous consumption when intrasexual competition is high. These findings are in line with recent literature that posits that testosterone is only related to particular decisions or behavior when status is at stake. In Study 1, we find that masculinized digit ratios (an indicator of high prenatal testosterone exposure) are only related to greater conspicuous consumption preferences for men that score high on an intrasexual competitiveness trait measure. In Study 2, we find that masculinized digit ratios are associated with greater conspicuous consumption preferences, but only among men who are primed with an intrasexual competition recall task. Finally, the purpose of Study 3 was to test if similar effects held when measuring circulating testosterone. We show that baseline levels of circulating testosterone are associated with greater conspicuous consumption preferences, but only after men are primed with intrasexual competition. Overall, we identify intrasexual competition as a crucial precondition for relationships between testosterone (prenatal and circulating) and conspicuous consumption to emerge. We argue that men with masculinized digit ratios and men with high circulating testosterone may be more likely to choose conspicuous products as a status‐signaling strategy in the mating market if they are inherently intrasexually competitive or when they encounter an intrasexually competitive situation.
Helianthus annuus assisted green synthesis of Co3O4 and Ag‐Co3O4 and evaluation of their catalytic activities toward photodegradation of crystal violet dye
Authors: Saeed Muhammad , Haq Atta Ul , Muneer Majid , Usman Muhammad , Naqvi Syed Ali Raza , Adeel Muhammad , Nisar Asif 
Published: January 2021

AbstractNowadays, plants assisted green synthesis of metal oxide nanoparticles attracted the interest of researchers due to economic and environmental points of view. This article reports the Helianthus annuus (sunflower) leaves assisted green synthesis of Co3O4 and Ag‐Co3O4 particles. In this method, the leaves extract of Helianthus annuus (sunflower) is utilized as a reducing and stabilizing agent for the synthesis of Co3O4 and Ag‐Co3O4 particles. XRD and FTIR confirmed the crystalline and spinel phase of prepared Co3O4 and Ag‐Co3O4 particles. The catalytic activities of prepared particles were evaluated over the photodegradation of crystal violet dye under visible irradiation. About 63% and 98% of 100 mg/L degraded over 0.002 g/ml of Co3O4 and Ag‐Co3O4, respectively. The reaction kinetics and mechanism were described in terms of the Eley‐Rideal mechanism. The rate constant was determined as 0.0075 and 0.0167 per minute for Co3O4 and Ag‐Co3O4, respectively.
Adsorptive degradation of hexavalent chromium from aqueous solution using coconut shell as a green adsorbent
Authors: Bal Dharmendra Kumar , Bhasarkar Jaykumar B. 
Published: January 2021

AbstractThe present study aimed to remove the heavy metal compounds present in wastewater. In this study, we used hexavalent chromium Cr (VI) as a heavy metal compound, and coconut shell was used as a promising green bio‐sorbent to remove Cr (VI) from wastewater. Coconut shells are readily available and are termed as waste materials. Various parameters such as contact time, pH of the solution, initial Cr (VI) concentration, and amount of coconut shell were studied. The adsorption data were fitted with various isotherm models. The Langmuir and Freundlich isotherm models were the best fit for the experimental data, and the maximum adsorption capacity was found to be 16.39 and 12.19 mg/g, respectively. Kinetic and thermodynamic studies were performed to assess the feasibility of the process. The pseudo‐second‐order kinetic model is also signified that the Cr (VI) adsorbent capacity was due to particle diffusion. To identify the morphological properties of the adsorbent various analysis such as Scanning Electron microscope (SEM) and BET surface area were performed. The experimental results and rate of adsorption, and the adsorption process was found to be feasible and endothermic in nature.
Mirabegron for treatment of overactive bladder symptoms in patients with Parkinson's disease: A double‐blind, randomized placebo‐controlled trial (Parkinson's Disease Overactive bladder Mirabegron, PaDoMi Study)
Authors: Cho Sung Yong , Jeong Seong Jin , Lee Sangchul , Kim Janghwan , Lee Seong Ho , Choo Min Soo , Oh Seung‐June 
Published: January 2021

AbstractAimsThis study aimed to investigate the efficacy and safety of mirabegron for Parkinsonism patients with overactive bladder (OAB) symptoms in a randomized, placebo‐controlled, multicenter study.Materials and MethodsInclusion criteria are Parkinsonism with OAB symptoms for 4 weeks or more, OAB symptom score (OABSS) questionnaire scores greater than 2, and OABSS urgency question scores greater than 1. After a 2‐week wash‐out period, the patients were randomized into placebo and mirabegron groups at visit 2. Visit 3 was performed after 4 weeks of medication. Mirabegron was prescribed to the two groups for the rest of the study period at visit 4.ResultThe mean age was 68.1 ± 8.1 years and 72 males and 64 females were included. A total of 136 patients were screened, 117 patients were randomized, and 25 patients dropped out. The OABSS scores were significantly different between the two groups at Weeks 4 and 8. The OABSS scores became the same in the two groups at Week 12 (visit 5). The postvoid residual urine volume showed a mild increase to 64 ml in the mirabegron group compared to the placebo group at visit 4. Adverse events occurred in 27 patients (23.1%). The degree was mild in 26 cases (78.8%), moderate in five (15.2%), and severe in two (6.1%). Only 13 cases (39.4%) showed medication‐related adverse events. Acute urinary retention occurred in a single case. The treatment satisfaction questionnaires showed no significant differences between the two groups.ConclusionMirabegron was effective in treating OAB symptoms in patients with Parkinsonism with acceptable adverse events.
Lattice automorphism and zero‐divisor graphs of lattices
Authors: Ülker Alper 
Published: January 2021

AbstractLet ℒ be a bounded lattice and α : ℒ → ℒ be its automorphism. In this paper, we study zero‐divisor graph of ℒ with respect to an automorphism α. It is a simple undirected graph and denoted by Γα(ℒ). Some combinatorial structures such as coloring, diameter and girth were given for Γα(ℒ).
Synthesis of 1,2‐Disubstituted Imidazole Derivatives as Potent Inhibitors of Mycobacterium tuberculosis and Their In Silico Studies
Authors: Nadaf AfraQuasar A. , Bulbule Sarojini R. , Yaseen Mohammed , Najare Mahesh S. , Mantur Shivaraj , Khazi Imtiyaz Ahmed M. 
Published: January 2021

AbstractA multi‐step synthetic protocol was employed to accomplish the synthesis of (2Z)‐2‐((E)‐4‐(benzylideneamino)phenyl)‐3‐(1‐methyl‐1H‐imidazol‐2‐yl)acrylonitrile derivatives. The title compounds were screened for antitubercular activity. Amongst them, three of the compounds appeared promising with a MIC value 0.2 to 0.4 μg/mL whereas the other compounds have also exhibited lower MIC than the standards. Docking study was performed to check their binding interaction and to deduce the possible mechanism of action involved in the inhibition process which revealed that the newly synthesized molecules act by inhibiting the DprE1 enzymatic pathway.
Multiple Modification of Titanium Dioxide to Enhance Its Photocatalytic Performance
Authors: Luo Xufei , Lai Wenchuan , Liu Xiangyang 
Published: January 2021

AbstractThe TiO2 nanocomposite photocatalyst P25/fluorinated graphene (P25/FG) was synthesized using the one‐step hydrothermal method. During hydrothermal process, the partial defluorination of FG, the surface fluorine doping of P25 as well as the deposition of P25 on graphene nanosheet were achieved. The P25/FG photocatalyst behaved excellent photocatalytic activity in photodegradation of methyl orange (MO) with degradation rate constant of 0.169 min−1, 5.6 times of that for P25 and 2.2 times for P25‐graphene catalyst under same conditions. It was demonstrated that the enhancement of photocatalytic activity of P25/FG can be attributed to the multiple modification of P25 brought by FG, including the effect of fluorine‐doped graphene, surface fluorine doping of P25 as well as dissociative fluorine ions in solution generated from UV‐assisted photocatalytic defluorination.
Design of a Non‐Cytotoxic ZnFe2O4‐CeO2/BRGO Direct Z‐Scheme Photocatalyst with Bioreduced Graphene Oxide as Cocatalyst
Authors: Barik Bapun , Maji Banalata , Bag Janmenjay , Mishra Monalisa , Singh Jaspreet , Dash Priyabrat 
Published: January 2021

AbstractHerein,we report the synthesis of a non‐cytotoxic ternary ZnFe2O4‐CeO2/bioreduced graphene oxide (BRZC) nanocomposite via in situ reflux method using a green solvent. The bioreduced graphene oxide (BRGO) used in the nanocomposite was obtained by reducing graphene oxide (GO) in Ocimum tenuiflorum leaf extract. Thourough structural, morphological, and photochemical characterizations revealed that the BRZC heterojunction possesses highly crystalline nanoparticles, enhanced surface reactive sites and suitable band arrangement for photon adsorption. Such a structure was found to bebeneficial in accelerating photocatalytic reaction synergistically by inhibiting charge carrier recombination. The BRZC nanocomposite showcased superior efficiency towards Chlorpyrifos (0.0634 min−1) andRhodamine B (0.0907 min−1) photodegradation. Detailed investigations revealed a most suitable internal electric field‐driven direct Z‐scheme mechanism between ZnFe2O4 and CeO2,where BRGO acts as a cocatalyst. After multiple photochemical and radical trapping experiments, .OH and O2.− were found to be the active species behind the enahnced activity. The ternary heterojunction was also found to be effective for highly toxic real textile effluents with 82 % degradation efficiency. Moreover, Trypan Blue Exclusion (TBE) assay study demonstrated the non‐cytotoxicity nature of the photocatalyst and a significant decrease in cytotoxicity of the above photocatalytically treated pollutants.
Synthesizing High‐quality Graphene from Spent Anode Graphite and Further Functionalization Applying in ORR Electrocatalyst
Authors: Ruan Dingshan , Zhang Zhenhua , Wu Xiaofeng , Wu Lin , Wang Fengmei , Zou Ke , Du Ke , Hu Guorong 
Published: January 2021

AbstractA novel green and low‐cost synthesis route converting spent graphite anode from lithium‐ion batteries (LIBs) into graphene nanosheets was reported for the first time. The impurities in spent graphite were eliminated by calcining and acidic leaching. Compared with the typical Hummers method, notable oxidation efficiency enhancement was observed through introducing a 5 : 1 mixed suspension of H2SO4 and H3PO4 with slightly increased KMnO4, then high‐quality graphene sheets were obtained through glucose, thermal reduction and subsequent liquid exfoliation. By simply and efficiently chemical nitrogen doping, graphene sheets showed excellent oxygen reduction catalytic performance, which is even better than commercial Pt/C catalyst, allowing it to be a promising low‐cost catalyst candidate for fuel cells. Since LIBs and fuel cell are considered as the major two power sources for electric vehicles in very near future, we believe that synthesizing few‐layer graphene with few defects and functionalized graphene catalyst from spent LIBs paves a path towards to the full utilization of battery materials and thus reduces impacts on environment from developing electric vehicles.
Risk‐based derivation of target reliability levels for life extension of wind turbine structural components
Authors: Nielsen Jannie S. , Sørensen John D. 
Published: January 2021

AbstractThe main wind turbine design standard IEC61400‐1 ed. 4 includes an annual target reliability index for structural components of 3.3. Presently, no standards specify specific reliability requirements for existing wind turbines, to be used in relation to verification of structural integrity for life extension or continued operation. For existing structures in general, both economic and sustainability considerations support differentiation in reliability targets, as it is generally more expensive and requires more resources to improve the reliability. ISO2394 “General Principles on Reliability for Structures” includes tables with differentiated reliability targets depending on the consequences of failure and costs of improving reliability, which are derived using risk‐based economic optimization. However, the assumptions behind these tables do not match the specific problem of life extension of wind turbines. In this paper, the risk‐based approach is applied to derive specific target reliability levels for life extension of wind turbines, and a target annual reliability index around 3.1 is proposed.