bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ontogenetic changes in the ventral colouration of post metamorphic Elachistocleis haroi Pereyra, Akmentins, Laufer, Vaira, 2013 (Anura: Microhylidae)
Authors: Bueno-Villafañe Diego , Caballlero-Gini Andrea , Ferreira Marcela , Netto Flavia , Fernández Ríos Danilo , Brusquetti Francisco 
Published: December 2019

Abstract
Ontogenetic colour change (OCC) is defined as the progressive and non-reversible process of changes in colouration of organisms associated with their development. Among the many vertebrate groups, amphibians are particularly impressive for their strikingly wide variety of colours, colour patterns, and signals, whose evolutionary and ecological significance have been poorly studied. Elachistocleis comprises 18 species currently separated into two main groups based on their ventral colour pattern: one immaculate and the other with specks and/or colour patches. Elachistocleis haroi is a small-sized species within the immaculate venter group, distributed in the Yungas and Dry Chaco ecoregions from which little information is known. In a comprehensive sampling of post-metamorphic individuals of E. haroi at different stages of development we identified a significant variation in ventral colour pattern, which could denote a progressive filling of yellow colour according to an ontogenetic pattern. To test this hypothesis, we analysed 39 post-metamorphic individuals of E. haroi at different stages of development with imaging procedures. We found that yellow spots and their intensity are significantly related to snout-vent length, as major expansion of colour on the sides, gular region and male chest, as almost no development on the belly. We briefly discuss our findings in relation to sexual display and predation avoidance. To our knowledge, this is the first analysis of post-metamorphic OCC in ventral colouration in the genus Elachistocleis.
Criminal Process faced with the Challenges of Scientific and Technological Development
Authors: Caianiello Michele 
Published: December 2019

This work examines some current-time challenges to the basic principles concerning fact-finding in criminal proceedings. The starting point of the analysis is that, no matter the theoretical model adopted in a criminal justice system, the essence of fair trial is that each party shall enjoy an effective chance to tell its story and to challenge the story and the theses proposed by the counterparts.
This approach to criminal proceedings, that we can synthetically define as inspired by the art of doubt, seems nowadays under attack, because of the recent developments at the scientific and technological levels, and of their implication to fact-finding models at trial. In particular, in a cultural and legal framework showing a decreasing sensitivity to the rights of the defence, the “doubt-based” or Socratic traditional approach seems defied by three factors: the digital revolution; the raise and spreading use of neurosciences; and the increasing employment of artificial intelligence in adjudicating cases. The thesis here submitted is that the traditional bases of fact-finding at trial can endure even against these challenges, as far as lawyers and scholars will be able to keep a critical and doubt-oriented approach to the new scientific and digital evidentiary instruments made available by the current development of technology.
Combining Microhistorical and Field Theory Approaches
Authors: Salter Elisabeth 
Published: December 2019

Abstract
The purpose of this article is to explore the frictions and potentials endemic in combining microhistorical and field theory approaches, using popular religion in England in the long fifteenth century as an example. In two case studies, concerning basic catechetical texts and the last wills and testaments created by a wide spectrum of the population, the article analyzes how micro- and macro-historical investigation can be tied together. Crucially, micro examples do not simply illustrate but rather add to our knowledge of the general picture. Where micro examples offer a corrective to a general picture there is potential for friction. However, the article also proposes that it is valuable to use Bourdieusian concepts of the cultural field to inventorize the micro evidence in the process of understanding historical situations and transitions more broadly.
The International Union of Social Studies of Malines and the Catholic Cultural Turn
Authors: Bosschaert Dries 
Published: December 2019

Abstract
The present article argues that the unexpected end of the Union de Malines’ Code de morale culturelle, an international collaboration of prominent twentieth-century Catholic moral theologians, should be attributed to three shifts in Catholic Social Teaching, only the first two of which the Union de Malines managed to undergo: from scholastic hegemony to theological diversity, from social doctrine to personalism, and from a juridical style of writing to a humanistic one. Particularly this last shift, introduced by the Second Vatican Council, proved to be a too big a leap for the Union, understood as a ‘little social tradition,’ to take. The cultural turn, which the Union de Malines had in fact anticipated, proved by the end of the council to belong to the future.
Greek στωμύλος ‘chatty’
Authors: Vine Brent 
Published: December 2019

Abstract
Gk. στωμύλος ‘chatty’ (Old Com.+) belongs with στόμα ‘mouth’; yet the serious formal problem with the -ω-, often acknowledged, remains without explanation. Part of the conundrum: despite the connection with στόμα (a synchronic n-stem and historically a men-stem), an n-stem or men-stem basis for στωμύλος is not workable. Two different solutions, however, can be proposed, on the basis of hitherto neglected Greek data; these point to the existence of forms that can support analyses in terms of vr̥ddhi (Solution #1) or in terms of a different type of morphological lengthened grade (Solution #2). These analyses, in turn, may shed light on the anomalous o-grade of Gk. στόμα itself, with broader implications for the study of PIE nominal morphology.
Hauchumsprung and the historical phonology of Greek *h
Authors: Sayeed Ollie 
Published: December 2019

Abstract
Ancient Greek underwent a sporadic sound change that copied an *h from the second syllable of a word to the first syllable, applying when the first syllable was vowel-initial, and perhaps also when it was stop-initial; this complements the analyses proposed so far in Greek historical phonology, particularly Sturm (2016, 2017), in accounting for the various sources of Proto-Greek *h. This change, Hauchumsprung, is unusual among recorded sound changes for involving the copying of a consonant over intervening material. Hauchumsprung, the φρουρᾱ́ rule, and Grassmann’s Law can be unified as three different footprints of a single sound change: one that copied aspiration from the middle of a word to the beginning of a word in early Greek.
The deviant typological profile of the Tocharian branch of Indo-European may be due to Uralic substrate influence
Authors: Peyrot Michaël 
Published: December 2019

Abstract
Tocharian agglutinative case inflexion as well as its single series of voiceless stops, the two most striking typological deviations from Proto-Indo-European, can be explained through influence from Uralic. A number of other typological features of Tocharian may likewise be interpreted as due to contact with a Uralic language. The supposed contacts are likely to be associated with the Afanas’evo Culture of South Siberia. This Indo-European culture probably represents an intermediate phase in the movement of speakers of early Tocharian from the Proto-Indo-European homeland in the Eastern European steppe to the Tarim Basin in Northwest China. At the same time, the Proto-Samoyedic homeland must have been in or close to the Afanas’evo area. A close match between the Pre-Proto-Tocharian and Pre-Proto-Samoyedic vowel systems is a strong indication that the Uralic contact language was an early form of Samoyedic.
On the homonymy of ‘put’ and ‘suck’ in Proto-Indo-European
Authors: de Vaan Michiel 
Published: December 2019

Abstract
PIE *dheh1- ‘to put, make’ and *dheh1-(i-) ‘to suck (mother’s milk)’ look like two separate verbal roots with a very different meaning, which happen to be homonymous. Yet recent investigations have shown that the morphological behaviour of both verbs is more similar than was previously thought. This article offers a re-evaluation of the evidence and explores the options to bridge the semantic gap between ‘put’ and ‘suck’.
A Harvard Physician’s Reports on an 1857 Visit to the Saamaka
Authors: Price Richard , Willoughby Christopher D.E. 
Published: December 2019

Abstract
In 1857, Harvard professor and anatomist Jeffries Wyman traveled to Suriname to collect specimens for his museum at Harvard (later the Peabody Museum of Archaeology and Ethnology, founded in 1866 and curated by Wyman). Though his main interest concerned amphibians, he had a secondary interest in ethnology and, apparently, a desire to demonstrate current theories of racial “degeneration” among the African-descended population, particularly the “Bush Negroes.” This research note presents a letter he wrote his sister from Suriname, excerpts from his field diary, and sketches he made while visiting the Saamaka and Saa Kiiki Ndyuka. Wyman’s brief account of his visit suggests that Saamakas’ attitudes toward outside visitors (whether scientists, missionaries, or government officials) remained remarkable stable, from the time of the 1762 peace treaty until the Suriname civil war of the 1980s.
Kreyòl anba Duvalier, 1957–1986
Authors: Robertshaw Matthew 
Published: December 2019

Abstract
The Duvalier presidencies were a devastating chapter in the history of Haiti. There is, however, one aspect of Haitian society that went through unexpected progress in the midst of these despotic regimes. Haitian Creole has long been excluded from formal and written contexts, despite being the only language common to all Haitians. The debate over whether Creole should be used in formal contexts for the sake of the country’s development and democratization began in earnest at the start of the twentieth century but was far from being resolved when François Duvalier came to power in 1957. Surprisingly, perceptions of Creole changed drastically during the Duvalier era, so that by the time Jean-Claude Duvalier fell from power in 1986 the status of Creole had improved markedly, so much that it had become typical for Haitians to use the language, along with French, in virtually all contexts.
Toward an Archeological Reconstruction of the Xia Dynasty as History: Delineations and Methods
Authors: Sun Qingwei , Van den Stock Ady 
Published: December 2019

Abstract
In a broad sense, the term “Xia culture” means the culture of the Xia dynasty [ca. 2100-1600 BCE] period. In a narrower sense, however, it refers to the culture of the Xiahou 夏后 clan of the mythical founder Yu 禹. In much of the contemporary research, the question of the primary ethnic affiliation of Xia culture is often overlooked and obscured, thus blurring the distinction between Xia culture in the broad and narrow senses. This has resulted in considerable conceptual and epistemological imprecision. Research on Xia culture can be conducted in two main ways: on the one hand, what has been called “metropolitan conjecture” and, on the other, cultural comparison. Departing from the method of cultural comparison and bringing together temporal, spatial, and cultural elements in our analysis allows us to distinguish a primary central area within the “region of Yu” that coincides with Xia culture in the narrow sense, as reflected in later phases of the Wangwan 王灣 and Meishan 煤山 regional subtypes of Longshan culture [Longshan wenhua 龍山文化], from the later phases of the various archaeological remains found within a secondary and tertiary central area, which can be included in the category of Xia culture in a broad sense. Erlitou 二里頭 culture should be regarded principally as part of Xia culture. As such, the Meishan and Wangwan subtypes of Henan Longshan culture, along with the first to the fourth phases of Erlitou culture, can be seen as making up a consistent Xia culture.
The Political Economy of Lulism and Its Aftermath
Authors: Braga Ruy , Barbosa dos Santos Fábio Luis 
Published: December 2019

President Dilma Rousseff’s impeachment should be framed as part of the crisis of the Lulist mode of regulation of social conflict. The Partido dos Trabalhadores (Workers’ Party—PT) presidencies lost their functionality from the standpoint of the interests of the traditional ruling classes of the country, led by the financial sector. The breakdown of Lulism was the exhaustion of the mediation between the predatory aspirations of the Brazilian bourgeoisie and the rights and aspirations of workers. This exhaustion was first evident in June 2013 and became acute in the subsequent years as the government was confronted with economic crises and corruption scandals. The Temer administration’s open confrontation of the working class pointed to a return of workers’ living conditions to the nineteenth century, but these measures reflected not a turning point but simply an acceleration of the pace of the prevailing politics. The collaboration of the ruling PT in confusing, calming, and alienating the popular classes helps explain the negligible popular reaction to the impeachment, the antipopular assault led by Temer, and Lula’s arrest. O impeachment da presidente Dilma Rousseff deve ser enquadrado como parte da crise do modo lulista de regulamentação dos conflitos sociais. As presidências do Partido dos Trabalhadores (PT) perderam sua funcionalidade do ponto de vista dos interesses das classes dominantes tradicionais do país, lideradas pelo setor financeiro. O colapso do lulismo foi o esgotamento da mediação entre as aspirações predatórias da burguesia brasileira e os direitos e aspirações dos trabalhadores. Essa exaustão ficou evidente pela primeira vez em junho de 2013 e se tornou aguda nos anos seguintes, quando o governo foi confrontado com crises econômicas e escândalos de corrupção. O confronto aberto do governo Temer com a classe trabalhadora apontou para o retorno das condições de vida dos trabalhadores ao século XIX, mas essas medidas refletiram não um ponto de virada, mas simplesmente uma aceleração do ritmo das políticas vigentes. A colaboração do PT no poder de confundir, acalmar e alienar as classes populares ajuda a explicar a insignificante reação popular ao impeachment, o ataque antipopular liderado por Temer e a prisão de Lula.
Community mobility plans for individuals with developmental disabilities: A feasibility study
Authors: Pfeiffer Beth , Falo Katelyn , Gallagher Laura , Kaufmann Christine , Li Jennie , Yabor Felicia 
Published: December 2019

Introduction Individuals with intellectual and/or developmental disabilities have unmet transportation needs, which limits their community mobility. Access to transportation is linked to community participation and independence in adult outcomes. The purpose of this study is to examine the implementation feasibility of individualized community mobility plans. Methods A pre-test post-test one group design was used to determine if methodology and implementation procedures were feasible. Outcome measures were evaluated to determine if appropriate for future effectiveness research. Participants were six adults with intellectual and/or developmental disabilities who received the community mobility plans intervention over a period of 3–8 sessions. Community mobility plans use a cyclical process where the individual first develops self-determined community mobility goals, followed by a comprehensive assessment process, and individualized environmental and person-centered travel interventions. Results Participants demonstrated significant improvement between pre- and post-test scores on the measures of the Progressive Evaluation of Travel Skills ( t(5) = –4.481, p = .007) and Goal Attainment Scaling ( t(5) = –7.457, p =.001). Conclusion Community mobility plans may provide a feasible option to improve community mobility for individuals with intellectual and/or developmental disabilities, although further research is needed to determine effectiveness.
Cellular distribution of PACAP-38 and PACAP receptors in the rat brain: Relation to migraine activated regions
Authors: Warfvinge Karin , Edvinsson Lars 
Published: December 2019

Background Pituitary adenylate cyclase-activating polypeptide (PACAP) occurs as either a 27- or 38-amino acid neuropeptide and belongs to the vasoactive intestinal polypeptide/glucagon/secretin family of peptides. PACAP and vasoactive intestinal polypeptide have a 68% homology of their amino acid sequences and share three B-type G-protein coupled receptors: VPAC1, VPAC2 and PAC1 receptors. Methods/results The distribution of PACAP-38 and its receptors in the brain is only partly described in the literature. Here, we have performed a study to provide the more general picture of this system in rat brain in order to understand a putative role in primary headaches and partly in relation to the calcitonin gene-related peptide system. We observed a rich expression of PACAP-38 and PAC1 receptor immunoreactivity in many regions throughout the cerebrum, cerebellum and brainstem. The expression pattern points to multiple functions, not least associated with pain and reactions to pain. The expression of VPAC1 and VPAC2 receptor immunoreactivity was very sparse. In several regions such as the cerebral cortex, trigeminal nucleus caudalis, hypothalamus and pons there was a close relation to calcitonin gene-related peptide expression. Conclusion The findings suggest that the rich supply of PACAP-38 and PAC1 receptors is associated with basic functional responses in the central nervous system (CNS), and there are important close anatomical relations with calcitonin gene-related peptide in CNS regions associated with migraine pathophysiology.
Toxic epidermal necrolysis associated with pembrolizumab
Authors: Cai Zhuo Ran , Lecours Julie , Adam Jean-Philippe , Marcil Isabelle , Blais Normand , Dallaire Mario , Belisle Annie , Mathieu Alexandre 
Published: December 2019

Introduction Stevens-Johnson syndrome and toxic epidermal necrolysis are severe cutaneous drug eruptions characterized by epidermal detachment. Pembrolizumab is a monoclonal antibody that binds to the programmed death-1 receptor, and it has been associated with numerous cutaneous adverse side-effects, including Stevens-Johnson syndrome. Case report We describe a 63-year-old male with metastatic lung adenocarcinoma who developed a rapidly progressing maculopapular rash three days after a first dose of pembrolizumab. On day 16, the rash affected more than 80% of body surface area with detachment of large sheets of necrolytic epidermis in 30–40% of body surface area. However, the patient only presented with mild mucosal involvement. Histopathologic examination of a skin biopsy showed a subepidermal blister with overlying prominent full thickness epidermal keratinocytic necrosis and a superficial perivascular infiltrate of lymphocytes. A toxic epidermal necrolysis secondary to pembrolizumab was then diagnosed. Management and outcome: In addition to supportive cares, the patient received corticosteroids and cyclosporine. The patient responded rapidly to the immunosuppressant therapy, and nearly complete re-epithelialization was achieved 24 days after the start of the reaction. Discussion In our review of the literature, 15 other cases of Stevens-Johnson syndrome/toxic epidermal necrolysis were reported with programmed death-1/programmed cell death ligand-1 inhibitors. To our knowledge, this is the first case of toxic epidermal necrolysis secondary to pembrolizumab published in the literature. The American Society of Clinical Oncology guidelines suggest that cyclosporine, in addition to corticosteroids, be initiated when toxic epidermal necrolysis is suspected. Clinicians should be aware of this rare dermatological emergency with the increasing use of pembrolizumab in oncology.
Necrotizing enterocolitis: It’s not all in the gut
Authors: Meister Alissa L , Doheny Kim K , Travagli R Alberto 
Published: December 2019

Necrotizing enterocolitis is the leading cause of death due to gastrointestinal disease in preterm neonates, affecting 5–12% of neonates born at a very-low birth weight. Necrotizing enterocolitis can present with a slow and insidious onset, with some neonates displaying early symptoms such as feeding intolerance. Treatment during the early stages includes bowel rest and careful use of antibiotics, but surgery is required if pneumoperitoneum and intestinal perforation occur. Mortality rates among neonates requiring surgery are estimated to be 20–30%, mandating the development of non-invasive and reliable biomarkers to predict necrotizing enterocolitis before the onset of clinical signs. Such biomarkers would allow at-risk neonates to receive maximal preventative therapies such as careful nutritional consideration, probiotics, and increased skin-to-skin care.Impact statementNecrotizing enterocolitis (NEC) is a devastating gastrointestinal disease; its high mortality rate mandates the development of non-invasive biomarkers to predict NEC before its onset. This review summarizes the pathogenesis, prevention, unresolved issues, and long-term outcomes of NEC.
Effects of Caveolin-1-ERK1/2 pathway on endothelial cells and smooth muscle cells under shear stress
Authors: Jia Lan , Wang Lihua , Wei Fang , Li Chen , Wang Zhe , Yu Haibo , Chen Haiyan , Wang Bo , Jiang Aili 
Published: December 2019

Hemodynamic forces have an important role in venous intimal hyperplasia, which is the main cause of arteriovenous fistula dysfunction. Endothelial cells (ECs) constantly exposed to the shear stress of blood flow, converted the mechanical stimuli into intracellular signals, and interacted with the underlying vascular smooth muscle cells (VSMCs). Caveolin-1 is one of the important mechanoreceptors on cytomembrane, which is related to vascular abnormalities. Extracellular signal-regulated kinase1/2 (ERK1/2) pathway is involved in the process of VSMCs proliferation and migration. In the present study, we explore the effects of Caveolin-1-ERK1/2 pathway and uremia toxins on the endothelial cells and VSMCs following shear stress application. Different shear stress was simulated with a ECs/VSMCs cocultured parallel-plate flow chamber system. Low shear stress and oscillating shear stress up-regulated the expression of fibroblast growth factor-4, platelet-derived growth factor-BB, vascular endothelial growth factor-A, ERK1/2 phosphorylation in endothelial cells, and proliferation and migration of VSMCs but down-regulated the Caveolin-1 expression in endothelial cells. Uremia toxin induces the proliferation and migration of VSMCs but not in a Caveolin-1-dependent manner in the static environment. Low shear stress-induced proliferation and migration of VSMCs is inhibited by Caveolin-1 overexpression and ERK1/2 suppression. Shear stress-regulated VSMC proliferation and migration is an endothelial cells-dependent process. Low shear stress and oscillating shear stress exert atherosclerotic influences on endothelial cells and VSMCs. Low shear stress modulated proliferation and migration of VSMCs through Caveolin-1-ERK1/2 pathway, which suggested that Caveolin-1 and ERK1/2 can be used as a new therapeutic target for the treatment of arteriovenous fistula dysfunction.Impact statementVenous intimal hyperplasia is the leading cause of arteriovenous fistula (AVF) dysfunction. This article reports that shear stress-regulated vascular smooth muscle cells (VSMCs) proliferation and migration is an endothelial cell (EC)-dependent process. Low shear stress (LSS) and oscillating shear stress (OSS) exert atherosclerotic influences on the ECs and VSMCs. LSS-induced proliferation and migration of VSMCs is inhibited by Caveolin-1 overexpression and extracellular signal-regulated kinase1/2 (ERK1/2) suppression, which suggested that Caveolin-1 and ERK1/2 can be used as a new therapeutic target for the treatment of AVF dysfunction.