bluuebunny/crossref_metadata_2025_split huggingface dataset:
Family-supportive organizational environment and turnover intention
Authors: Taheri Fatemeh 
Published: October 2020

PurposeThe purpose of this paper is to test a model in which family-supportive organizational environment is associated with lower levels of turnover intention through higher levels of work-family enrichment and job satisfaction.Design/methodology/approachBased on a sample of 300 employees, the bootstrap procedure for estimating indirect correlations in multiple mediator models was used to test the research hypotheses.FindingsThe results suggest that employees experiencing high levels of family-supportive organizational environment are likely to report lower intention to leave their profession by virtue of their higher levels of job satisfaction and work-life enrichment.Research limitations/implicationsThe study is limited to public organization and sample size. Further research is needed to make comparison between large/state-owned and small/private organizations.Practical implicationsIn the Iran context, work-family enrichment and job satisfaction are effective in reducing the employees' turnover intention. Organizations should show concerns for the employees' work-life enrichment and job satisfaction to reduce their turnover intention.Social implicationsTurnover is one of the problems of organizations in many countries throughout the world including Iran, which has negative consequences through increasing the cost of organizations. The results of this study suggest ways in which staff retention could be improved.Originality/valueThe present study contributes to supportive organizational environment literature by addressing the relationship between family-supportive organizational environment and employee-related outcomes. Given some commonalities between Iran and other developing countries, the findings might be of potential interest in comparative studies dealing with the employees' turnover issue.
Contextualizing “traditional crafts” in historic urban areas
Authors: Jigyasu Niyati 
Published: October 2020

PurposeTraditional crafts, practised by local communities, contribute significantly towards intangible heritage. The study situates traditional crafts in historic urban areas, establishes its relevance and deliberates on the factors affecting it.Design/methodology/approachThe methodology included questionnaire survey followed by semi-structured interviews. On-site observations were also taken as part of the methodology.FindingsThe study contextualizes traditional crafts in historic areas and throws light on the transformation processes in these crafts due to socio-cultural, economic, political and other factors. Through studies at three different historic settlements, it provides a wider understanding of the dynamics of the same craft in different setting.Practical implicationsThe study would help in formulating guidelines for heritage management with respect to traditional crafts in historic urban areas.Social implicationsThe study brings out the role of intangible cultural heritage that is inherent to the local communities in historic urban areas.Originality/valueTraditional crafts have been largely studied in their independent context. This study looks at the context specific to the place of creation of these crafts within the larger ecosystem of raw material-production-sale in historic urban areas. Also, with discussions on intangible heritage in context of the historic urban areas being largely an unexplored territory till recent times, this study will add to the earlier dialogue.
Processes of value co-creation in networks: an empirical study of local business networks in Denmark
Authors: Rasmussen Mette Apollo 
Published: October 2020

PurposeThere is no agreement in the network literature about how participating in networks is of value. This article aims to explore the underlying dynamics that form and support the process of value co-creation in networks.Design/methodology/approachThe article draws together symbolic interactionism and organizational ethnography to outline a research approach illustrating how participation in networks becomes valuable. The empirical data were collected through fieldwork over two in two local business networks in Denmark.FindingsThe case study illustrates how participants in local business networks struggle to make participation valuable. The article shows how networks can be considered joint spheres for value co-creation. Three main arguments supporting value in networks stands out from the research: (1) Leadership as a collective achievement supports processes of value co-creation; (2) Develop a shared but dynamic focus and (3) Participation is valuable when supporting participants' daily worklife.Originality/valueThe article builds up a creative analytical framework based on symbolic interactionism making an important contribution about how participants experience value in networks.
An exploratory study of teacher buoyancy
Authors: Wong Angel Kit Yi , Tang Sylvia Yee Fan , Li Dora Dong Yu , Cheng May May Hung 
Published: October 2020

PurposeThe purpose of this paper is threefold. Firstly, a new concept, teacher buoyancy, is introduced. Based on the significance to study how teachers bounce back from minor and frequent setbacks (vs. major adversities emphasized in resilience) in their daily work and the research on buoyancy by Martin and Marsh, a dual-component framework to conceptualize this new concept is introduced. Secondly, the development of a new instrument, the Teacher Buoyancy Scale (TBS), to measure it is presented. Thirdly, results of a study using the TBS are reported, which provide insights into how teacher buoyancy can be fostered.Design/methodology/approachThe study employed a quantitative design. A total of 258 teachers taking a part-time initial teacher education (ITE) program completed the TBS. Their responses were analyzed by exploratory factor analysis (EFA). In addition to descriptive statistics and reliability coefficients, Pearson correlation coefficients were calculated to examine the relationship among the factors.FindingsThe data analysis indicated five factors, namely, Coping with difficulties, Bouncing back cognitively and emotionally, Working hard and appraising difficulties positively, Caring for one's well-being and Striving for professional growth. These factors can be readily interpreted by the dual-component framework. Correlations among the factors further revealed that enabling factors can be subdivided into more proximal personal strengths relating to direct coping, and more distal personal assets pertaining to personal well-being. It is the latter that correlates most highly with perceived teacher buoyancy.Originality/valueThe most original contribution of this paper is the proposal of the new concept of teacher buoyancy which is teachers' capacity to deal with the everyday challenges that most teachers face in their teaching. The delineation between buoyancy and resilience sharpens the focus of the problem domain that is most relevant to teachers. The development of the TBS provides a useful and reliable instrument to examine teacher buoyancy in future studies.
Communicating influence: positioning the trainer as an organizational leader
Authors: Mathis Robin Smith 
Published: October 2020

PurposeThis study aims to examine participants’ perspectives in organization-sponsored training and provides support for further research positioning the trainer as an organizational leader.Design/methodology/approachThe interactions described in the trainees’ experiences were examined through a social constructivist lens. Interviews were conducted to collect data. Narratives were analyzed to reach interpretation.FindingsInterview results identified four themes, namely, relevance and applicability of training received, the formation of attitudes and preferences among the trainee participants, immediacy in the use of the training received and relational and organizational influence that furthers leader-member exchange in the workplace.Research limitations/implicationsThis study examined participants’ perspectives in workplace training and provides support for further research: examining communication’s role in workplace learning; exploring the training process; and positioning the trainer as an organizational leader.Practical implicationsThis study provides empirical data to support changes in instructional communication models and exploring the process of training. Trainers’ relational building with trainees could impact many outcomes in their training efforts that are detailed in this study.Originality/valueThis study uses a collection of methods to address the trainees’ experience in formal workplace learning. It demonstrates the power of trainers to influence what the trainees think of training content, format and relational learning.
Research at home: Being creative in running an undergraduate final research project in Food Science amidst the COVID‐19 crisis
Authors: Surya Reggie 
Published: October 2020

AbstractThe pandemic of coronavirus disease (COVID‐19) in early 2020 has led to tremendous disruptions in education systems worldwide, including the closure of majority of education institutions and the shifting from face‐to‐face learning toward remote learning. More than 70% of the world's student population were affected by such a disruptive event, inclusive of undergraduate students in their final year preparing their research project. Senior students in Food Science generally perform laboratory‐oriented research project, which can be problematic due to the closure of laboratories and universities. I wrote this article to give an insight into conducting final year research projects from home amidst the COVID‐19 crisis based on my personal experience as a research supervisor. The research methods discussed include literature review, analysis of secondary data, survey research, simple food processing, remote sensory evaluation, and glycemic index analysis. Regardless of the type of research chosen, consistent guidance and support from a research supervisor toward the student, both academic and moral, appears to be a fundamental factor determining the success of the student in completing his/her final research project, particularly during these difficult times.
Evaluation of cognitive function in adult patients with juvenile idiopathic arthritis
Authors: Mena‐Vázquez Natalia , Cabezudo‐García Pablo , Ortiz‐Márquez Fernando , Díaz‐Cordovés Rego Gisela , Muñoz‐Becerra Luis , Manrique‐Arija Sara , Fernández‐Nebro Antonio 
Published: October 2020

AbstractObjectiveTo evaluate cognitive function in adult patients with juvenile idiopathic arthritis (JIA) and associated factors.Patients and methodsWe performed a cross‐sectional observational study of adult patients with JIA and a healthy control group (no inflammatory diseases) matched for age, gender, and educational level. Cognitive function was assessed using Wechsler Adult Intelligence Scale‐III. The cognitive domains measured were attention/concentration, verbal function, visuospatial organization, working memory, and problem solving (Similarities). Other measures included clinical‐epidemiological characteristics, comorbid conditions, and treatment. We performed a descriptive bivariate analysis and logistic regression to identify factors associated with visuospatial involvement.ResultsThe study population comprised 104 subjects (52 with JIA and 52 healthy controls). Patients with JIA had poorer results for visuospatial function, with a lower median scaled score on the Block Design test (5.0 [4.0‐8.0] vs 8.0 [5.0‐10.0]; P = .014). The number of patients with scaled scores below the average range (<8) in visuospatial organization was significantly greater in the JIA group (67.3% vs 40.4%; P = .006). The multivariate analysis revealed time since diagnosis (odds ratio [95% CI], 1.03 [1.01‐1.06]), inflammatory activity according to Juvenile Arthritis Disease Activity Score 27‐joint count (1.94 [1.01‐3.75]), and educational level (0.28 [0.08‐0.94]) to be factors associated with visuospatial function.ConclusionCognitive function in adult patients with JIA is poorer than in healthy controls at the expense of visuospatial function. Visuospatial function in JIA patients was inversely associated with disease duration, inflammatory activity, and lower educational level.
Remarkable response to dacomitinib in a patient with leptomeningeal carcinomatosis due to EGFR‐mutant non‐small cell lung cancer
Authors: Mizusaki Shun , Otsubo Kohei , Ninomiya Toshifumi , Arimura Hidenobu , Tsuchiya‐Kawano Yuko , Inoue Koji 
Published: October 2020

Dacomitinib, a second‐generation epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitor, is a standard therapeutic option for patients with EGFR‐mutant non‐small cell lung cancer (NSCLC). However, its efficacy in patients with central nervous system lesions is unclear. Here, we describe a case of EGFR‐mutant NSCLC whose neurological symptoms were due to leptomeningeal carcinomatosis that was successfully treated with dacomitinib. After initiation of dacomitinib, the neurological symptoms of the patient were remarkably improved and leptomeningeal dissemination and brain metastases were shown to have regressed on magnetic resonance imaging (MRI) scan. To our knowledge, this is the first report showing the efficacy of dacomitinib in a patient with leptomeningeal carcinomatosis due to EGFR‐mutant NSCLC. The current case suggests that dacomitinib is a novel treatment option for patients with EGFR‐mutant NSCLC accompanied by central nervous system lesions, even those with symptomatic leptomeningeal carcinomatosis.Key pointsSignificant findings of the studyThis is the first report showing the efficacy of dacomitinib in a patient with leptomeningeal carcinomatosis due to EGFR‐mutant NSCLC.What this study addsThe current case suggests that dacomitinib is a novel treatment option for patients with EGFR‐mutant NSCLC accompanied by CNS lesions, even in those with symptomatic leptomeningeal carcinomatosis.
Activation of the cannabinoid receptor type 2 by the agonist JWH133 promotes the first wave of in vitro spermatogenesis
Authors: Dumont Ludovic , Rives‐Feraille Aurélie , Delessard Marion , Saulnier Justine , Rondanino Christine , Rives Nathalie 
Published: October 2020

AbstractBackgroundOncological procedures have irreversible side effects on germ cells for childhood cancer survival boys. In vitro culture of prepubertal testicular tissue has been proposed to restore fertility; however, recent data on animal models showed that meiotic and post‐meiotic progression was impaired.ObjectivesAs potential key inducers of the mitosis‐meiosis switch, type 2 cannabinoid receptor (CB2) has been proposed to play a central role in the meiotic entry of male germ cells. Herein, the in vitro first spermatogenesis wave in mice was used to understand the impact of CB2 activation on the differentiation of spermatogonia until elongated spermatids.Materials and methodsA first set of cultured testicular explants of 6.5 days post‐partum (dpp) mice was performed to assess the impact of a range of JWH133 supplementation (10 nm, 100 nm, 1 µm, 10 µm). Then, the progressive development of germ cells at key timepoints of spermatogenesis was evaluated throughout (i) in vitro culture (day 2 [D2], D3, D6, D10, D18, and D30) coupled with (ii) in vivo counterparts (8.5, 9.5, 12.5, 16.5, 24.5, and 36.5 dpp).ResultsCB2 was detected at the plasma membrane of cells, and a successful completion of spermatogenesis was obtained in vitro. One day after the activation of CB2 by 1 μm of the agonist JWH133, percentage of zygotene spermatocyte I increased.ConclusionAfter 30 days of culture, (i) an enrichment of haploid germ cells detected by flow cytometry, (ii) a reduced necrotic area, and (iii) an increase in the density of post‐meiotic germ cells were observed. We showed that the activation of CB2 improves in vitro entry into meiosis and differentiation of spermatogonia, mimicking physiological meiotic transition.
Impact of obesity on short‐term outcomes of laparoscopic colorectal surgery for Japanese patients with colorectal cancer: A multicenter study
Authors: Yamashita Mariko , Tominaga Tetsuro , Nonaka Takashi , Fukda Akiko , Moriyama Masaaki , Oyama Syosaburo , Tanaka Kenji , Hamada Kiyoaki , Araki Masato , Sumida Yorihisa , Takeshita Hiroaki , Hisanaga Makoto , Fukuoka Hidetoshi , Wada Hideo , Tou Kazuo , Sawai Terumitsu , Nagayasu Takeshi 
Published: October 2020

AbstractIntroductionThe impact of obesity on short‐term outcomes after laparoscopic colorectal surgery (LAC) in Asian patients is unclear. The purpose of the present multicenter study was to evaluate the safety and feasibility of LAC in obese Japanese patients.MethodsWe retrospectively reviewed 1705 patients who underwent LAC between April 2016 and February 2019. Patients were classified according to body mass index (BMI): non‐obese (BMI < 25 kg/m2, n = 1335), obese I (BMI 25‐29.9 kg/m2, n = 313), and obese II (BMI ≥30 kg/m2, n = 57). Clinical characteristics and surgical outcomes were compared among the three groups.ResultsThe proportion of patients with comorbidities (non‐obese, 58.1%; obese I, 69.6%; obese II, 75.4%; P < .001) and median operation time (non‐obese, 224 minutes; obese I, 235 minutes; obese II, 258 minutes; P = .004) increased significantly as BMI increased. The conversion rate was similar among the groups (P = .715). Infectious complications were significantly high in obese II patients (non‐obese, 10.4%; obese I, 8.3%; obese II, 28.1%; P < .001). Multivariate analysis revealed that in obese II patients, BMI was an independent predictive factor of infectious postoperative complications (odds ratio 2.648; 95% confidence interval, 1.421‐4.934; P = .002).Conclusion: LAC has an increased risk of postoperative infectious complications in obese II patients, despite improvements in surgical technique. Management of obese II colorectal cancer patients requires meticulous perioperative management.
Task persistence in kindergarten children: Disentangling age from schooling effects
Authors: Oeri Niamh , Roebers Claudia M. 
Published: October 2020

The aim of the present study was to examine age effects and schooling effects on task persistence. Four‐ and 5‐year‐old (N = 120) kindergarten children were observed while working on a persistence task. Since children attend kindergarten for 2 years in Switzerland, age and schooling effects could be examined in a cut‐off research design. To examine age effects, task performance was compared between 4‐ and 5‐year‐olds, all enrolled in their first kindergarten year. To address schooling effects, performance between 5‐year‐olds enrolled in their first vs. 5‐year‐olds enrolled in their second kindergarten year was compared. Age differences were found for two different persistence measures. No effect was found for schooling. Overall, the present results suggest that 1 year of formal kindergarten schooling, as a structuring environmental factor, does not affect the ability to persist. Age and inhibitory skills, however, do.
Activation of dopaminergic VTA inputs to the mPFC ameliorates chronic stress‐induced breast tumor progression
Authors: Xu Xi‐Rong , Xiao Qian , Hong Yu‐Chuan , Liu Yun‐Hui , Liu Yue , Tu Jie 
Published: October 2020

AbstractAimsChronic stress plays an important role in promoting the progression and migration of cancers. However, little is known of any direct impact on tumor progression related to the regulation of emotion‐related circuitry. The aim of this study was to explore the neural‐circuit mechanisms underlying stress‐induced progression of cancers and the impact of emotion‐related regulation of circuitry on tumor growth.MethodsOptogenetic manipulation was applied to unpredictable chronic mild stress (UCMS)–treated mice bearing breast tumor cell. The stress‐related hormones, tumor‐related cytokines, the tyrosine hydroxylase (TH)–positive neurons and their fibers, dopamine receptor–positive cells, and anxiety level were measured using ELISA, immunohistochemical staining, fluorescence in situ hybridization, and behavioral test, respectively.ResultsBy investigating breast cancer mouse models with a chronic mild stress model, optogenetic stimulation, and behavioral analysis, we show that chronic stress induced anxiety‐like behavior in mice and increased serum concentration of norepinephrine and corticosterone, hormones closely related to stress and anxiety. Optogenetic activation of VTA TH terminals in the mPFC rescued anxiety‐like behavior induced by chronic stress. Chronic stress resulted in marked progression of breast tumors, and repetitive optogenetic activation of VTA TH terminals in the mPFC significantly attenuated stress‐induced progression of breast cancers and reduced serum concentration of norepinephrine and corticosterone. Furthermore, there was a positive correlation between serum norepinephrine or corticosterone concentration and tumor size.ConclusionsThese findings indicate a positive role of an emotion regulation circuit on the progression of breast cancer and reveal a link between stress, emotion regulation, and the progression of breast cancers. Our findings provide new insights pertinent to therapeutic interventions in the treatment of breast cancers.
Feasibility of manual bronchial branch reading technique in navigating conventional rEBUS bronchoscopy in the evaluation of peripheral pulmonary lesion
Authors: Kho Sze Shyang , Nyanti Larry Ellee , Chai Chan Sin , Chan Swee Kim , Tie Siew Teck 
Published: October 2020

AbstractBackgroundAlthough radial endobronchial ultrasound (rEBUS) is an important verification tool in guided bronchoscopy, a navigational route was not provided. Manual airway mapping allows the bronchoscopist to translate the bronchial branching in computed tomography (CT) into a comparable bronchoscopic road map. We aimed to explore the feasibility of this technique in navigating conventional rEBUS bronchoscopy in the localisation of peripheral pulmonary lesion by determining navigation success and diagnostic yield.MethodsRetrospective review of consecutive rEBUS bronchoscopy performed with a 6.2 mm conventional bronchoscope navigated via manual bronchial branch reading technique over 18 months.ResultsNinety‐eight target lesions were included. Median lesion size was 2.67 cm (IQR 2.22‐3.38) with 96.9% demonstrating positive CT bronchus sign. Majority (86.7%) of lesions were situated in between the third and fifth airway generations. Procedure was performed with endotracheal intubation in 43.9% and fluoroscopy in 72.4%. 98.9% of lesions were successfully navigated and verified by rEBUS following the pre‐planned airway road map. Bidirectional guiding device was employed in 29.6% of cases. Clinical diagnosis was secured in 88.8% of cases, majority of which were malignant disease. The discrepancy between navigation success and diagnostic yield was 10.1%. Target PPL located within five airway generations was associated with better diagnostic yield (95.1% vs. 58.8%, P < 0.001). There was 1 (1.0%) pneumothorax in our cohort.ConclusionsManual bronchial branch reading technique in combination with conventional rEBUS is feasible in localisation of PPL, especially for lesions located within the first five airway generations