bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical application of the 2011 IFCPC colposcope terminology in the era of HPV vaccines
Authors: Zhang Bei , Hong Shuhui , Zhang Guihui , Rong Fengnian 
Published: December 2020

Abstract
Background Colposcopy is the conjunction with screening and diagnosis of cervical precancerous lesions. However the diagnostic accuracy of colposcopy is unsatisfied. This study was to evaluate colposcopic accuracy according to the 2011 International Federation of Cervical Pathology and Colposcopy (IFCPC) terminology.Methods A retrospective cohort study was performed in 1,838 patients who underwent colposcopy in Shandong Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University from October 2013 to April 2018. Using conization or cervical biopsy pathology as the gold standard, the agreement between colposcopic diagnosis and pathologic diagnosis was calculated, and correlations between variables were analyzed. Results As an authoritative and widely used terminology for colposcopy diagnosis, the 2011 IFCPC terminology has certain clinical practicality and diagnostic accuracy. However, some signs such as mosaic, punctuation, sharp border, inner border sign and ridge sign had high specificity but unsatisfactory sensitivity, which limited the diagnostic value. Therefore, we discussed the Lugol’s staining, a very common sign in colposcopy, and analyzed the diagnostic significance of bright yellow staining in low-grade squamous intraepithelial lesion (LSIL) and mustard yellow staining in high-grade squamous intraepithelial lesion (HSIL). The results showed that mustard yellow may be a valuable indicator in the diagnosis of HSIL. Conclusion With the wide acceptance of human papilloma virus (HPV) vaccines and HPV-based screening, there will be new challenges to accurately identify the signs of non-HPV16 and non-HPV18 infections and of minor lesions using colposcopy. In this study, we provide some recommendations in dealing with these challenges. More clinical research will be needed to further refine colposcopy terminology, improve diagnostic accuracy, and ensure that the World Health Organization’s goal of eliminating cervical cancer worldwide by 2030 is achieved.
Serum tumour markers combined with clinicopathological characteristics for predicting MMR and KRAS status in 2279 Chinese colorectal cancer patients: a retrospective analysis
Authors: Zhao Ning , Cao Yinghao , Yang Jia , Li Hang , Wu Ke , Wang Jiliang , Peng Tao , Cai Kailin 
Published: December 2020

Abstract
Background

Although serum tumour markers (STMs), clinicopathological characteristics and the status of KRAS and MMR play an important role in optimizing the treatment and improving the prognosis of colorectal cancer, their interrelationships remain largely unknown.
Methods

A retrospective analysis of 2279 patients who underwent KRAS or MMR status testing and STM measurements prior to treatment over the past four years was conducted. Univariate and multivariate logistic regression were performed to identify independent predictive factors of KRAS and MMR status. The area under receiver operating characteristic (ROC) curve (AUC) was used to evaluate the predictive value of individual and combined factors.
Results

Of the 784 patients tested for KRAS and 2279 patients tested for MMR status, KRAS mutations and dMMR were identified in 276 patients (35.20%) and 177 patients (7.77%), respectively. Logistic regression analysis demonstrated that right colon, well and moderate differentiation and negative CA19-9 were independent predictors for KRAS mutations. The ROC curve yielded an AUC of 0.609 for the combination of the three factors. Age < 65 was an independent predictive factor for dMMR, along with tumour size > 4.6 cm, right colon, poor differentiation, harvested lymph nodes ≥ 22, no lymph node metastasis, no perineural invasion, negative CEA and positive CA72-4. When the nine criteria were used together, the AUC was 0.849.
Conclusion

Both STMs and clinicopathological characteristics were found to be significantly associated with the status of KRAS and MMR. The combination of these two factors possessed a strong predictive power for targeted genes among CRC patients.
Cuidar en el archivo de arquitectura: una subversión matrística
Authors: Rodríguez López Luz Marie 
Published: December 2020

<p class="p1">La historia de la arquitectura y su archivo suelen conectar con registros patriarcales y de colonialidad que sustentan el epistemicidio. Subvertir el archivo de arquitectura hegemónico podría mediar en la redefinición y reajuste de los límites y ópticas de las narrativas históricas. Desde el cuidar, el archivo matrístico (antipatriarcal, antihegemónico) disiente e instiga contra el discurso oficial que designó los sures como territorios sin razón, sin producción de conocimiento, sin historia y sin arquitectura.<span class="Apple-converted-space"> </span></p>
Diabetes mellitus asociada al uso crónico de antipsicóticos atípicos
Authors: Argoty Chamorro Giovanny Armando , Rodríguez Lopéz Laura Melissa , Vallejos Narváez Álvaro Argoty 
Published: December 2020

Los agentes antipsicóticos son considerados como el principal tratamiento farmacológico para el manejo de mantenimiento y el tratamiento de casos agudos de la esquizofrenia y otros trastornos mentales. Estos medicamentos están clasificados en dos grupos: los antipsicóticos de primera generación o antipsicóticos típicos (AT) y los antipsicóticos de segunda generación o antipsicóticos atípicos (AA). En relación con el uso de los antipsicóticos típicos (AT), se han descrito importantes efectos adversos, sobre todo síntomas extrapiramidales (EPS), lo cual ha relegado su uso y fomenta el mayor empleo en la práctica clínica de los antipsicóticos atípicos (AA) gracias a la adecuada efectividad clínica demostrada hasta el momento. Sin embargo, estos medicamentos están asociados con diferentes alteraciones metabólicas, entre las cuales se encuentra un mayor riesgo de diabetes; para lo cual se han propuesto varios mecanismos etiopatogénicos. En esta revisión narrativa, se presenta un resumen actualizado de la literatura de los últimos 5 años sobre el uso de antipsicóticos atípicos y la diabetes mellitus tipo 2, haciendo énfasis en las diferentes hipótesis reportadas hasta el momento que involucran el aumento de peso y diferentes efectos mediados por hormonas, receptores de neurotransmisores y neuropéptidos que impactan en la génesis de los estados hiperglucémicos y de insulinorresistencia.
Factores demográficos y clínicos que explican la progresión de la enfermedad renal crónica en un programa de nefroprotección del departamento de Nariño, Colombia 2016-2018
Authors: Bastidas Bertha Ligia Bernal , Quirós Gómez Oscar Ivan 
Published: December 2020

Introducción: La Enfermedad Renal Crónica es una patología de gran impacto en salud pública a nivel mundial, su progresión está determinada por limitaciones en el control de sus factores de riesgo y pronóstico. Los programas de nefroprotección hacen seguimiento y control de los pacientes con la enfermedad, intentando llevarlos a cumplir las metas específicas de nefroprotección para limitar la progresión de la Enfermedad Renal Crónica.
Objetivo: Determinar los factores explicativos de la progresión de la Enfermedad Renal Crónica en pacientes atendidos en un programa de nefroprotección.
Materiales y métodos: Estudio analítico observacional de cohorte retrospectivo en 5872 pacientes con Enfermedad Renal Crónica en diferentes estadios, participantes de un programa de nefroprotección en el departamento de Nariño durante el período 2016-2018. La progresión de la ERC, correspondió a la disminución de la Tasa de Filtración Glomerular en 5mL/min/1.73 m2 o más. La información se obtuvo de la base de datos del programa. Se construyó un modelo explicativo ajustado por variables demográficas y clínicas. Acorde al diseño se utilizó un modelo binomial con función de enlace logarítmica para estimar los coeficientes de regresión de las variables de interés. Las medidas de asociación fueron los Riesgos Relativos.
Resultados: el 72,2% fueron mujeres, el 75,1% tenían 60 años o más, el 12,4% eran afrocolombinos, y el 85% mestizos, se presentó progresión el 49,2% (IC 95% 47,9-50,4) de los casos. Los factores que mejor explicaron la relación la progresión de ERC, fueron: ser hombre con un RR ajustado de 1,04 (IC95%:1,00-1,15), y tener un estadio de la ERC, de 4, 5 y 3a-b, con RR ajustado 1,62 (IC1,36-1,94) y 1,41 (IC1,21-1,63) respectivamente.
Conclusiones: En la población nariñense de Colombia afiliada a un programa de nefroprotección, la progresión de la ERC fue del 49,2%, siendo explicada de forma significativa por el sexo masculino, y los estadios avanzados de la enfermedad.
QUALIFICANDO OS PROCESSOS DE LEITURA E ESCRITA DOS ALUNOS EM UMA ESCOLA MUNICIPAL DE ARROIO GRANDE
Authors: Leal Sabrina Caetano Fernandes 
Published: December 2020

O projeto de intervenção teve como objetivo: Despertar nos alunos, do 8º ano do Ensino Fundamental II, o gosto pela leitura e pela escrita, nas disciplinas de Produção Textual e Português. Sobre isso, Silva (1991) indica que a leitura simboliza uma ação para que se possa produzir o saber, isso permite a percepção e a apreensão sobre as analogias que existem.De acordo com Martins (1994), o aprendizado serve para produzir a ampliação de horizontes para o leitor, de maneira que ele possa compreender seu mundo e institua reações que possam gerar transformações. Consequentemente, a leitura e conhecimento são considerados por Martins (1994) processos interventivos de progressos para suas vidas. No que lhe diz respeito, a coletividade procurar informação através da leitura envolve localizar um embasamento sustentável para o desenvolvimento social.Bakhtin (2002) também destaca a seriedade da leitura indissociada do social. Portanto, o intercâmbio verbal entre pessoas, possibilitada por meio da utilização da língua pelo falante e concebe o princípio criador da linguagem e apresenta modo dialógico.Portanto, a leitura e a escrita são práticas que se arrolam e se completam, os educandos são ledores em formação, esses processos deverão estar vinculados aos métodos de leitura que são ampliadas na escola. Dessa forma, a leitura e a escrita abrangem metodologias indissociáveis na prática discursiva, em que ler é um procedimento de cultivo de conhecimentos, a relevância de observar a leitura como prática social.Optei por essa temática, porque vivencio essa problemática em sala de aula, onde os estudantes demonstram pouca afinidade com a leitura e escrita, e uma enorme lacuna para produzirem textos com coerência e coesão.Relato que algumas das dificuldades dos processos de Produção Textual encontrados por mim em minha prática como docente das Áreas de Linguagens são as que envolvem o vocabulário empobrecido, carregado de gírias que os estudantes apresentam em suas produções, como o pouco domínio da língua culta, evidenciam as dificuldades de expressar suas ideias no papel, pois os alunos consideram o aspecto quantitativo ao invés do qualitativo para elaborarem suas escritas.Por ser professora de Português e Produção Textual, percebo com mais intensidade a aversão dos alunos por qualquer atividade que abranja o ato de ler, pois os discentes, em sua grande maioria, apresentam textos precários e uma grande desmotivação em relação à leitura e a escrita, dessa maneira penso que haja necessidade de se trabalhar diferentes formas de aproximar os alunos de atividades que promovam a leitura e escrita dentro da sala de aula.Através dessa intervenção organizei ações que despertem o interesse dos alunos por essa temática, através de rodas de conversas com pessoas da comunidade que já possuem uma vasta trajetória nesse assunto, em que enfatizam em suas produções a preocupação em apresentar o livro para formar mais leitores.
Coronavirus: Penyakit Lama, Virus Lama, Kemasan Baru
Authors: Wijono Heru 
Published: December 2020

Abstract— Covid -19, a virus strain and a member of family with known member as Severe Acute Respiratory Disease (SARS) or Middle East Respiratory Syndrome (MERS), but having a potentially lethal differences in not readily recognized by our immunity. Classified as betacoronavirus, with incubation period up to 14 days, the sign and symptoms can be highly variable, from asymptomatic to mild to criticalin the form of severe pneumonia. Almost half the persons infected did not show any symptoms, but in cases of people with comorbidities such as advanced age, pregnancy, obesity or other certain diseases, could increase the likelihood of morbidity and even potentially fatal. Covid-19 has spread globally, including Indonesia, with a potentially increased number of cases, prevention in covid-19 protocol is a necessity. Keywords: Covid-19, SARS, symptoms, variable, prevention
Abstrak— Covid-19, yang sebelumnya dikenal sebagai virus strain dari kelompok family yang sama dengan Severe Acute Respiratory Disease (SARS) atau Middle East Respiratory Syndrome (MERS), tapi memiliki fatalitas yang secara potensial lebih tinggi, karena bersiafat novel bagi sistem imunitas kita. Termasuk betacoronavirus, dengan masa inkubasi sampai dengan 14 hari, tanda dan gejala penyakit bisa sangat bervariasi, mulai dari asimtomatik, ringan sampai berat, dalam bentuk pneumonia berat. Hamper separuh penderita yang terinfeksi tidak menunjukkan gejala sama sekali, tapi pada penderita dengan komorbiditas seperti usia lanjut, kehamilan, obesitas atau penyakit kronis tertentu, resiko moribiditas dan mortalitas dapat meningkat. Covid-19 saat ini sudah menyebar ke seluruh dunia, termasuk Indonesia, dengan adanya potensi kenaikan kasus lebih banyak, pencegahan dalam bentuk protocol covid-19 bersifat mutlak diperlukan. Kata kunci: Covid-19, SARS, gejala, bervariasi, pencegahan
Maia type fixed point results via C-class function
Authors: Ansari Arslan Hojat , Khan Mohammad Saeed , Rakočević Vladimir 
Published: December 2020

Abstract
In 1968, M. G. Maia [16] generalized Banach’s fixed point theorem for a set X endowed with two metrics. In 2014, Ansari [2]introduced the concept of C-class functions and generalized many fixed point theorems in the literature. In this paper, we prove some Maia’s type fixed point results via C-class function in the setting of two metrics space endowed with a binary relation. Our results, generalized and extended many existing fixed point theorems, for generalized contractive and quasi-contractive mappings, in a metric space endowed with binary relation.
Generalized operator for Alexander integral operator
Authors: Güney H. Özlem , Owa Shigeyoshi 
Published: December 2020

Abstract
Let T
n
be the class of functions f which are defined by a power series

f

(
z
)

=
z
+

a

n
+
1

z

n
+
1

+

a

n

2

z

n
+
2

+
…

f\left( z \right) = z + {a_{n + 1}}{z^{n + 1}} + {a_n}2{z^{n + 2}} + \ldots

for every z in the closed unit disc

𝕌
¯

\bar {\mathbb{U}}

. With m different boundary points z
s, (s = 1,2,...,m), we consider α
m
∈ e
iβ𝒜−j−λf(𝕌), here 𝒜−j−λ is the generalized Alexander integral operator and 𝕌 is the open unit disc. Applying 𝒜−j−λ, a subclass B
n
(α
m
,β,ρ; j, λ) of T
n
is defined with fractional integral for functions f. The object of present paper is to consider some interesting properties of f to be in B
n
(α
m
,β,ρ; j, λ).
On some Hall polynomials over a quiver of type ˜D4
Authors: Szántó Csaba , Szöllősi István 
Published: December 2020

Abstract
Let k be an arbitrary field and Q a tame quiver of type ˜D4. Consider the path algebra kQ and the category of finite dimensional right modules mod-kQ. We determine the Hall polynomials F
xy
z
associated to indecomposable modules of defect ∂z =−2, ∂x = ∂y =−1 or dually ∂z = 2, ∂x = ∂y = 1.
Artillery from the Perspective of Firing Effects and Ensured Capabilities
Authors: Oprean Laurean-Georgel 
Published: December 2020

Abstract
Artillery is a branch capable of effectively supporting the dynamic operations performed by combat forces, with a decisive role in neutralizing, destroying or annihilating the opponent’s capabilities, harassing and banning the actions of troops by executing a precise, effective and timely fire to obtain the expected effects. It uses high-tech subsystems and intelligent ammunition, while the concentration of fire and means is flexible, and the possibility of measuring and evaluating the effects on the target is high, due to the precise means of identification, research, selection and tracking a multitude of fixed or mobile land targets, either planned or unplanned. The ability of the artillery to act in the composition of joint tactical groups gives it an additional utility at tactical level, while the actions of the artillery are complex and ubiquitous in stability and peacekeeping operations, even near the contact alignment, with a strong impact for a wider range of scenarios.
First record of Lichtenstein’s Sandgrouse Pterocles lichtensteinii in Lebanon, 2020
Authors: Sawan Michel 
Published: December 2020

Abstract
The Lichtenstein’s Sandgrouse (Pterocles lichtensteinii) is a nomadic, mostly nocturnal species. Its world range includes several countries in Africa, as far south as Kenya, and Asia as far east as Pakistan, but within the Middle East, it is a resident in Egypt, Southern Israel and Jordan, Saudi Arabia, Yemen, Oman and Southern Iran. Like other members of its family, it is found in very dry habitats including wadis and stony deserts. Seeing a flock of them in Lebanon is extraordinary. They were sighted for the first time in the country. The dry hot wind in that time of the year might have brought them there. A poacher shot the flock and killed six birds during night hunting.
SoK: Managing Longitudinal Privacy of Publicly Shared Personal Online Data
Authors: Schnitzler Theodor , Mirza Shujaat , Dürmuth Markus , Pöpper Christina 
Published: December 2020

AbstractOver the past decade, research has explored managing the availability of shared personal online data, with particular focus on longitudinal aspects of privacy. Yet, there is no taxonomy that takes user perspective and technical approaches into account. In this work, we systematize research on longitudinal privacy management of publicly shared personal online data from these two perspectives: user studies capturing users’ interactions related to the availability of their online data and technical proposals limiting the availability of data. Following a systematic approach, we derive conflicts between these two sides that have not yet been addressed appropriately, resulting in a list of challenging open problems to be tackled by future research. While limitations of data availability in proposed approaches and real systems are mostly time-based, users’ desired models are rather complex, taking into account content, audience, and the context in which data has been shared. Our systematic evaluation reveals interesting challenges broadly categorized by expiration conditions, data co-ownership, user awareness, and security and trust.
Single-Stage Treatment of Aneurysm of the Distal Aortic Arch and Proximal Descending Aorta Using the Frozen Elephant Trunk Procedure. Case Report
Authors: Jovev Sasko , Papestiev Vasil , Shokarovski Marjan , Hadzievska Stefanija , Mehmedovic Nadica , Lazovski Nikola , Filipce Venko , Risteski Petar 
Published: December 2020

Abstract
Aneurysms of the thoracic aorta involving the distal arch and the proximal descending aorta have traditionally been treated with two open procedures. During the first stage, the aortic arch pathology has been addressed through a median sternotomy. Several weeks or months later, a second stage followed and included completing the repair of the descending aorta through a lateral thoracotomy.
We, herein, report a single stage repair of an aneurysm involving the distal aortic arch and the proximal descending aorta using the frozen elephant trunk operative technique. Vascular hybrid stent graft prosthesis, specifically designed for treatment of extensive aortic aneurysms, has been used to replace the arch component and exclude the descending aorta component of the aneurysm through a median sternotomy, using bilateral antegrade cerebral perfusion and mild systemic hypothermia for intraoperative organ protection.
Learning new words’ emotional meanings in the contexts of faces and sentences
Authors: Gu Beixian , Liu Bo , Wang Huili , Beltrán David , de Vega Manuel 
Published: December 2020

Abstract
Language is a powerful vehicle for expressing emotions, although the process by which words acquire their emotional meaning remains poorly understood. This study investigates how words acquire emotional meanings using two types of associative contexts: faces and sentences. To this end, participants were exposed to pseudowords repeatedly paired either with faces or with sentences expressing the emotions of disgust, sadness, or neutrality. We examined participants’ acquisition of meanings by testing them in both within-modality (e.g., learning pseudowords with faces and testing them with a new set of faces with the target expressions) and cross-modality generalization tasks (e.g. learning pseudowords with faces and testing them with sentences). Results in the generalization tests showed that the participants in the Face Group acquired disgust and neutral meanings better than participants in the Sentence Group. In turn, participants in the Sentence Group acquired the meaning of sadness better than their counterparts in the Face Group, but this advantage was only manifested in the cross-modality test with faces. We conclude that both contexts are effective for acquiring the emotional meaning of words, although acquisition with faces is more versatile or generalizable.
Problemy mieszkaniowe w procesach rewitalizacji na przykładzie województw: opolskiego, świętokrzyskiego i warmińsko-mazurskiego
Authors: Basińska Paulina 
Published: December 2020

AbstraktW artykule zaprezentowano wyniki badania przeprowadzonego w drugim kwartale 2020 r. Analizą objęto wskaźniki wykorzystywane na poziomie delimitacji obrazujące problemy mieszkaniowe w województwach: opolskim, świętokrzyskim i warmińsko-mazurskim. Zagadnienie to jest ściśle powiązane z silną depopulacją i poważnymi problemami demograficznymi obserwowanymi we wskazanych województwach. Celem artykułu jest przedstawienie skali problemu związanego z sektorem mieszkaniowym wyrażonego poprzez wskaźniki wykorzystywane do analizy sfery technicznej w diagnozie delimitacyjnej. Dzięki przeprowadzonej analizie stwierdzono jedynie częściowe odzwierciedlenie problemu mieszkalnictwa w opracowanych diagnoza delimitacyjnych.