bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glomerular diseases related to HIV in Colombian population: Better outcomes with highly active antiretroviral therapy?
Authors: Muñoz-Velandia Oscar , García-Peña Ángel , Garzón-Herazo Javier , Contreras-Villamizar Kateir , Rodríguez-Sánchez Martha , Garcia-Consuegra Elias , Toro-Trujillo Esteban 
Published: October 2020

Introduction: End-stage renal disease (ESRD) related to HIV is becoming a leading cause of renal replacement therapy requirement is some areas of the world. Our study aims to describe the incidence and renal outcomes of HIV-associated nephropathy (HIVAN), and immune-mediated kidney disease related to HIV (HIVICK) in Colombia.
Methodology: A retrospective cohort study was performed, including all HIVAN or HIVICK incident cases assessed by the infectious diseases division in a high complexity institution in Colombia, between 2004 and 2018. A longitudinal data model under the Generalized Estimating Equations (GEE) method was used to determine changes on the glomerular filtration rate (GFR) over time.
Results: Within a cohort composed by 1509 HIV-infected patients, we identified 22 with HIV-associated glomerular disease. Cumulative incidence was 1.45%. At diagnosis, GFR was above 30 mL/min in 90.8% of patients, and 77.2% displayed sub-nephrotic proteinuria. Factors associated with GFR at diagnosis were: level of CD4 (Coefficient 0.113, CI 95 %: 0.046, 0.179, p < 0.01), and the inverse of the CD4/CD8 ratio. The GEE model did not demonstrate significant changes in the GFR over a 3-year period. Findings were similar when comparing GFR at diagnosis with GFR at 12 (-3.9 mL/min/1.73m2, CI 95% -7.3, 0.4, p = 0.98), 24 (-2.47 mL/min/1.73m2, CI 95% -7.0, 2.1, p=0.85), and 36 months (0.39 mL/min/1.73m2, CI 95% -4.4, 5.2, p = 0.43) of follow-up.
Conclusions: Patients with glomerular disease associated with HIV have stable GFR over a 3-year period, and low rates of progression towards dialysis requirement. Differences with previous reports could be related with early diagnosis and treatment with highly active antiretroviral therapy.
Biological activities of essential oil extracted from leaves of Atalantia sessiflora Guillauminin Vietnam
Authors: Le Nhan Trong , Donadu Matthew Gavino , Ho Duc Viet , Doan Tuan Quoc , Le Anh Tuan , Raal Ain , Usai Donatella , Sanna Giuseppina , Marchetti Mauro , Usai Marianna , Diaz Nicia , Rapelli Paola , Zanetti Stefania , Cappuccinelli Piero , Nguyen Hoai Thi 
Published: October 2020

Introduction: The present study aimed to determine the chemical compositions and bioactivities of the essential oil of Atalantia sessiflora Guillaumin (A. sessiflora), including antibacterial, antimycotic, antitrichomonas, anti-inflammatory and antiviral effects.
Methodology: The essential oil from leaves of A. sessiflora was extracted by hydrodistillation using a Clevenger apparatus. Chemical compositions of oil were identified by GC/MS. Antimicrobial and antitrichomonas activity were determined by the microdilution method; anti-inflammatory and antiviral were determined by the MTT method.
Results: The average yield of oil was 0.46 ± 0.01% (v/w, dry leaves). A number of 45 constituents were identified by GC/MS. The essential oil comprised four main components. The oil showed antimicrobial activities against Gram-positive strains as Staphylococcus; Gram-negative bacteria such as Klebsiella pneumoniae and Escherichia coli; and finally four Candida species. Enterococcus faecalis and Pseudomonas aeruginosa were least susceptible to the oil of A. sessiflora, as seen in their MIC and MLC values over 16% (v/v). Activity against Trichomonas vaginalis was also undertaken, showing IC50, IC90 and MLC values of 0.016, 0.03 and 0.06% (v/v) respectively, after 48 hours of incubation. The oil of A. sessiflora displayed activity against the nitric oxide generation with the IC50 of 95.94 ± 6.18 µg/mL. The oil was completely ineffective against tested viruses, ssRNA+, ssRNA-, dsRNA, and dsDNA viruses.
Conclusions: This is the first yet comprehensive scientific report about the chemical compositions and pharmacological properties of the essential oil of A. sessiflora. Further studies should be done to evaluate the safety and toxicity of A. sessiflora oil.
Les scores polygéniques pangénomiques comme nouvelle forme de mesure de l’humain
Authors: Dheur Sonia , Saupe Sven J. 
Published: October 2020

Chez l’homme, les études d’association pangénomiques basées sur les programmes génomiques institutionnels et commerciaux permettent aujourd’hui d’identifier des polymorphismes génétiques (SNPs) associés à des traits complexes de nature psychosociale et déterminés par des centaines de gènes différents (le niveau d’instruction, l’intelligence, des traits psychotiques, névrotiques et émotionnels…). L’enjeu immédiat n’est plus l’identification du lien causal et mécanistique qui explique la contribution d’un SNP à un trait mais la construction d’outils métrologiques nouveaux désignés scores polygéniques pangénomiques . Ces scores proposent d’exprimer en une valeur numérique unique la capacité d’un génome donné à produire un trait complexe. Ces scores deviennent des outils analytiques et prédictifs censés traduire la potentialité génétique d’une personne par rapport à ces traits psychosociaux et conduisent ainsi à une biologisation statistique de « l’exception humaine ».
« Sous vos pas, un parfait agencement » : la transformation du paysage énergétique urbain de Montréal, 1890-1950
Authors: Hatton-Proulx Clarence 
Published: October 2020

À rebours des études qui considèrent l’invisibilité comme une composante invariable de l’infrastructure, cet article propose une étude historique des manières dont la présence physique de l’énergie a évolué dans la métropole du Canada d’alors, Montréal, sur plus de soixante ans. Pour fixer le cas à l’étude, il s’appuie d’abord sur les plans d’assurance afin de documenter l’évolution de l’emprise spatiale de l’énergie en contextes résidentiel et industriel, constatant la disparition graduelle du bois et du charbon au profit du pétrole, du gaz et de l’hydroélectricité, soit des formes d’énergie distribuées en réseau. Il offre ensuite une analyse fine de la vive controverse autour des réseaux aériens de fils et de poteaux qui menaçaient autant les corps que l’ordre économique au tournant du XX e siècle. Le rôle des différents acteurs, en particulier celui joué par l’industrie de l’assurance incendie, dans la trajectoire sinueuse menant vers l’enfouissement encadré par la municipalité est analysé. Ces résultats empiriques permettent de complexifier le concept d’invisibilité tel qu’appliqué à l’infrastructure, soutenant que celui-ci est historiquement, géographiquement et socialement situé. Il faut plutôt comprendre l’invisibilité comme un principe vers lequel tendent les planificateurs des systèmes que comme une caractéristique invariable de l’infrastructure. La possibilité d’accomplissement de ce principe dépend d’un contexte social et économique propice, comme celui qui s’est manifesté à Montréal à la fin des années 1900 et qui est présenté dans cet article.
Mobiliser et transformer l’industrie de la mode pour préserver la biodiversité
Authors: Daveu Marie-Claire , Vallejo Géraldine , Ole-Moiyoi Katrina 
Published: October 2020

Partout dans le monde, la nature décline à un rythme sans précédent dans l’histoire de l’humanité. Nous sommes sortis d’un « espace opérationnel sûr » au regard des limites planétaires établies par la science et, à moins que l’humanité ne prenne des mesures « transformatives », pas moins d’un million d’espèces sont menacées d’extinction dans les décennies à venir. L’industrie de la mode, avec des chaînes d’approvisionnement mondiales très complexes, doit jouer un rôle de premier plan dans la réponse à donner. Non seulement l’industrie dépend presque entièrement des biens et services fournis par la nature, mais elle est également responsable d’impacts relativement importants sur les écosystèmes naturels. Répondre à cette crise nécessite de comprendre la matérialité des impacts, de fixer des objectifs ambitieux, d’améliorer les pratiques d’approvisionnement et de révolutionner production des matières premières et modèles économiques dominants. La crise de la biodiversité est l’un des plus grands défis auxquels notre génération est confrontée. Elle nécessite un degré de collaboration sans précédent de l’industrie pour « inverser la courbe » de la perte de biodiversité, et ce de toute urgence.
L’interprétation transactionnelle de la Constitution anglaise : le libéralisme réformiste de Sismondi
Authors: Pasquiet-Briand Tanguy 
Published: October 2020

Curieusement délaissée par les juristes, l’œuvre du Genevois Sismondi contient pourtant des développements, certes disséminés, d’une rare acuité sur les évolutions institutionnelles de l’Europe du premier xix e siècle en général, et sur les transformations du parlementarisme britannique en particulier. Toutefois, dans la cohérence du libéralisme coppétien dont il est l’un des artisans majeurs aux côtés de Germaine de Staël et de Benjamin Constant, Sismondi n’échappe pas, à propos du régime politique anglais, à une tendance idéaliste qui tend à ériger ce dernier en modèle sociopolitique. La présentation qu’il dresse de ce régime épouse en effet sa philosophie de l’histoire, dont le récit se propose de joindre un conservatisme porté sur un aristocratisme historique et sur un libéralisme centré sur le développement de l’individu face à l’inéluctable démocratie.
Endoscopic and clinical correlation with dose to sigmoid colon in carcinoma cervix patients treated with radical radiotherapy
Authors: Elagandula Jyosthna , Arulponni T. R. 
Published: October 2020

Context:
Sigmoid colon, due to its close proximity to central tandem in intracavitary brachytherapy (BT), is at risk of receiving high dose, the clinical significance of which is not documented.

Aim:
This study was designed to assess the dose received by sigmoid colon following radical treatment and to correlate clinically with the sigmoid mucosal changes seen on sigmoidoscopy.

Settings and Design:
This is a prospective study.

Subjects and Methods:
Thirty histologically proven carcinoma cervix patients treated with radical radiotherapy were accrued. A baseline sigmoidoscopy was done and repeated at 6 months following completion of BT. The dose–volume parameters (DVP) were used to calculate the dose received by the sigmoid colon and correlate with symptoms along with the sigmoid mucosal changes.

Statistics:
The following were the statistical methods used: frequency; percentages; and descriptive statistics such as mean ± standard deviation, Chi-square test, Kolmogorov–Smirnov test, and independent sample t-test. P < 0.05 was considered statistically significant.

Results:
The dose of the sigmoid colon in patients with a sigmoidoscopy score of ≥2 was significantly high compared to that of patients with a score of <2 for DVP such as D0.1cc, D1cc, D2cc, D5cc, and mean dose, whereas max dose was not significantly high.

Conclusions:
The dose received by the sigmoid colon is directly proportional to the mucosal changes and hence possibly a higher morbidity. Tighter dose–volume constraints, better optimization techniques, and close follow-up sigmoidoscopy will help in the prevention and early treatment of long-term morbidity.
Association between Serum Homocysteine Levels and Methylene-Tetrahydrofolate-Reductase Gene Polymorphism in Patients with Stroke
Authors: Chouksey Dinesh , Ishar Hashash Singh , Jain Rahul , Athale Sunil , Sodani Ajoy 
Published: October 2020

Background:
Hyperhomocysteinemia (HHcy) is a well-established risk factor for vascular thrombosis leading to stroke. Homocysteine (Hcy) is mainly synthesized in the methionine cycle, and it is an intermediate during the conversion of methionine to cysteine. HHcy can develop by polymorphism of several enzymes like methylene-tetrahydrofolate-reductase (MTHFR) mutation and due to deficiency of co-factor Vitamins such as B12, B6, and folic acid. This study was planned to see the association between HHcy and MTHFR gene polymorphism in patients with stroke in populations from central India.

Methods:
Seventy-two patients diagnosed with stroke aged 18 years and above who met the inclusion criteria were selected. Hcy level and MTHFR mutation were identified among patients of stroke.

Results:
Forty-two patients (58.33%) were diagnosed with acute ischemic stroke as compared to cerebral venous thrombosis (30, 41.66%) from a total of 72 patients. The statistical analysis projected that the HHcy diagnosed among more (45, 62.5.0%) cases with stroke who had aged ≤45 years as compared to cases who had aged >45 years (17, 23.6%). None of our patients tested positive for either CT (Heterozygous) or TT(Homozygous) genotypes.

Conclusions:
HHcy is not associated with MTHFR gene mutation in our study group, and this possibly is related to the deficiency of co-factors in Hcy metabolism. Young age group stroke patients have higher Hcy levels.
Reliability and Validity of the Turkish Version of the Movement Imagery Questionnaire-3
Authors: Dilek Burcu , Ayhan Çiğdem , Yakut Yavuz 
Published: October 2020

Objective:
Motor imagery (MI) is the mental representation of a movement without any body movement, and it has been recently used as a therapeutic intervention in rehabilitation. The Movement Imagery Questionnaire-3 (MIQ-3) is the most recent, modified version of the MIQ-revised, second edition, which is commonly used to measure the imagery ability of patients with movement dysfunction. The purpose of the study was to translate the MIQ-3 into Turkish and evaluate its test and retest reliability and validity for the Turkish-speaking population.

Methods:
Among 185 healthy participants, 181 completed the procedures. The questionnaire was applied to 86 participants with 1-week interval to evaluate internal consistency and test–retest reliability. The construct validity of the MIQ-3 was tested by confirmatory factor analysis (CFA).

Results:
The internal consistency of the Turkish MIQ-3 was satisfactory (Cronbach's alpha was 0.87 for test and 0.86 for retest reliability). The internal consistency of subscales for test–retest reliability (internal visual items, external visual items, and kinesthetic items) was 0.73–0.68, 0.74–0.72, and 0.79–0.73, respectively. Test–retest reliabilities of each item ranged from 0.84 to 0.95. In terms of criterion validity, there was an excellent correlation between subscales and total scale correlations, which ranged from 0.50 to 0.90 (P < 0.001). The validity of the MIQ-3 was examined with CFA, and the results supported a three-factor model of movement imagery ability.

Conclusion:
The Turkish MIQ-3 has an excellent reliability and good-to-excellent validity in evaluating MI ability.
Analyse de la gouvernance des petites et moyennes entreprises familiales de la ville de Bukavu en République démocratique du Congo
Authors: Mmenge A. , Binwa B. , Gahungu D. 
Published: October 2020

Les PME évoluent dans un environnement en perpétuelle évolution, celui-ci oblige les dirigeants de mettre en œuvre des plans d’actions susceptibles d’orienter les actions vers les objectifs visés, de manière à être compétitif et créer de la richesse. L’objectif decette étude était d’analyser et mesurer la gouvernance des PMEF de la ville de Bukavu en République Démocratique du Congo. L’échelle utilisée montre les bonnes propriétés psychométriques(X2=19.42 ; P=0.6766 ; X2/ddl= 0.84 CFI=0.99; IFI=0.99; RMSEA=0.000; NFI=0.92; GFI=0.97 et AGFI=0.94).Cette étude a analysé les données primaires collectées sur 132PMEFde la ville de Bukavu. Le traitement des données a été obtenu en recourant à l’analyse factorielle exploratoire et confirmatoire et au tri à plat. Les résultats indiquent que la gouvernance est un construit à neuf items regroupés en quatre dimensions (la parcimonie, leparticularisme, la personnification et le système de gestion)qui expliquent 68.394 pourcent de la variance totale. Ils montrent que les validités convergente et discriminante sont assurées (CR=0.826 et AVE=0.6 ; et AVE supérieure au coefficient de corrélation partielle entre les variables). Ils révèlent aussi que les PMEF disposent les avis partagés sur l’importance de la gouvernance et leurs dirigeants disposent la difficulté de mettre en place une bonne gouvernance.
Analysis of lipid profile of catfish (<i>Clarias albopunctatus</i>) from selected water bodies in Ebonyi State, Nigeria
Authors: Nwabunike M.O. , Igwe G.V.C. , Agama I.K. , Esheya C.E. , Nwite C.O. 
Published: October 2020

The study analyzed the lipids of catfish, (Clarias albopunctatus) from four rivers (Mkpuma, Amaka, Enyigba and Ebonyi) in Ebonyi State. Fishes were harvested, weighed and sacrificed and the gill tissues were collected and used for the extraction of lipid for the analysis. All extracted lipids were homogenized in a chloroform-methanol solution using standard procedure. After extraction, lipids were resolved and analyzed differently while simple correlation was used to analyze the data collected. Results showed that there were varying levels of lipid composition among the catfish samples from the different rivers. Results further revealed the correlation between triglyceride (TG) and other lipids to be only significant for phosphatidylcholine (PC) (r=0.818, p<0.05). Although TG had moderate correlation with sphingomyelin (SM), the correlation was not significant (r=0.701, p>0.05). Free fatty acid (FFA) had strong positive significant correlation with cholesterol (CHO) (r=0.981, p<0.01); sphingomyelin (SM) (r=0.949, p<0.01) and phosphatidylethanolamine (PE) (r=0.886, p<0.01). However, moderate correlation with no significant difference (0.631, p>0.05) was observed with phosphatidylcholine (PC). Cholesterol also had strong positive correlation with SM and PE and insignificant correlation with PC while a strong positive correlation was observed between SM and PC (r=0.828, p<0.01).
Keywords: Lipid profile, catfish, water bodies, Ebonyi State, correlation.
Effects of pre-treatment with extracts of <i>Ocimum gratissimum </i>and <i>Vermonia amygdalina</i> on proximate and organoleptic properties of processed <i>Clarias gariepinus</i> (Burchell, 1822)
Authors: Ojukannaiye S.A. , Agbabiaka L.A. , Adedokun I.I. 
Published: October 2020

The study evaluated nutritional and organoleptic properties of Clarias gariepinus pre-treated with aqueous leave extracts of Ocimum gratissimum and Vernonia amygdalina before processing. Thirty-six (36) C. gariepinus (live weight = 1.2± 0.2kg) samples were procured and processed for the study. Fish samples were divided into three parts of twelve fish each. Each part was grouped into three treatments having four fish in each group using a completely randomized design. Treatment one (T1) had fish immersed in 5% brine without herbal extract (control). In Treatment two (T2), fish were soaked in mixture of 5% brine and 5% O. gratissium (scent leaf) extracts while Treatment three (T3) had fish soaked in mixture of 5% brine and 5% V. amygdalina (bitter leaf) extracts all for 30 minutes. Treated fish samples were smoke-dried using charcoal kiln for 5 hours at temperature of 80 – 90° C. Samples were then cooled under ambient condition (30+3oC) for 4 hours. The smoke-dried fish samples were labeled according to treatments and stored for 7 days under aseptic condition. Organoleptic properties of the samples were conducted at every 24-hour of storage using a 9-point hedonic scale. Mean values of proximate composition of samples were significantly different (p<0.05). Protein content (70.01%) in T3 was higher than 68.31% and 66.62% in T2 and T1 respectively. Similarly, fat (5.12%) and ash (4.68%) levels for T3 were higher than 4.85% and 4.46% fat with 4.36% and 3.98% ash contents for T2 and T1 respectively. Results of mean scores for each organoleptic property decreased significantly (p<0.05) during storage period with no consistent trend in score pattern.
Keywords: Clarias gariepinus, extract pretreatment, Ocimum gratissimum, organoleptic, Vernonia amygdalina.
Igwebuike theology of <I>Ikwa ogwe</I> and the inculturation of the gospel message
Authors: Kanu Ikechukwu Anthony 
Published: October 2020

This piece on Igwebuike theology of Ikwa Ogwe has attempted at building a bridge between two conflicting inheritances or worldviews of the African Christian: the western heritage and the heritage of his or her ancestors. The researcher attempted doing this with maturity and creativity, and without destabilizing the wholeness of the African Christian. It defined Igwebuike theology contextually, and the Igwebuike concept of culture as a preparation for the gospel, basing this on Clement of Alexandria’s Stromata. This created a basis for an Igwebuike theology of Ikwa Ogwe. It argued that until this bridge is built, the Word of God cannot be effectively communicated- in such a way that the people hearing the Word understand who they are and who others are. It observed that communicating the Gospel without building a bridge would rather take people away from themselves, thus, creating a problem of identity. It discovered that the major task of the gospel message, which is the transformation of worldviews and conceptual systems would not be adequately achieved without Ikwa Ogwe. Igwebuike theology of Ikwa Ogwe, therefore, emphasizes identifying with the people and communicating the message through their categories. The purpose of this study is to make a contribution to the ongoing efforts at resolving the cross-cultural conflicts of the missionary era. The theoretical framework employed is the Igwebuike holistic and complementary understanding of evangelization and culture, which focuses on the bigger picture of reality and believes that all parts of reality are interconnected.
Keywords: Igwebuike, Theology, Ikwa Ogwe, Missionary Enterprise, Culture, Conflicts
Otizm Spektrum Bozukluğu Olan Çocukların Antropometrik Ölçümlerinin Değerlendirilmesi
Authors: ÇİFTÇİ Çağla 
Published: October 2020

Amaç: Bu araştırma Otizm Spektrum Bozukluğu tanısı almış çocukların antropometrik ölçümlerinin değerlendirilmesi amacıyla yapılmıştır.Yöntem: Araştırmanın evrenini Bursa’da bir özel eğitim ve rehabilitasyon merkezinde eğitim almakta olan 63 Otizm Spektrum Bozukluğu olan çocuk oluşturmakta olup, örneklem seçimine gidilmemiştir. Gönüllülük esasına dayalı olarak 50 otistik çocuk araştırma kapsamına alınmıştır. Çalışmaya katılan çocukların vücut ağırlıkları ve boy uzunlukları ölçülüp, Beden Kitle İndeksi değerleri hesaplanmıştır. Elde edilen veriler persentil eğrilerine göre değerlendirilmiştir. Bulgular: 36’sı erkek ve 14’ü kız olan çocukların yaş ortalaması 11.49±4.51’dir. Beden Kitle İndeksi değerlerine göre çocukların %4’ü zayıf, %36’sı normal, %18’i hafif şişman ve %42’si şişmandır.Sonuç: Sonuç olarak, OSB’li çocuklarda hafif şişman ve şişmanlığın yüksek olduğu belirlenmiştir.
Gebelikte Yaşanan Reflünün Yaşam Kalitesi ve Gebelik Uyumuna Etkisi: Vaka-Kontrol Çalışması
Authors: AMANAK Keziban 
Published: October 2020

Amaç: Bu çalışma, gebelikte yaşanan reflünün yaşam kalitesi ve gebelik uyumuna etkisini incelemek amacıyla yapılmıştır.Yöntem: Araştırma uygun örnekleme ile seçilen gebelikte reflüsü olan (vaka grubu) 112, gebelikte reflüsü olmayan (kontrol grubu) 112 olmak üzere, toplam 224 gebe ile yürütülmüştür. Araştırma verileri, Kişisel Bilgi Formu, Yaşam Kalitesi Ölçeği ve Prenatal Kendini Değerlendirme Ölçeği-Gebeliğin Kabulü Alt Ölçeği ile toplanmıştır. Bulgular: Araştırmada, vaka grubundaki gebelerin kontrol grubundaki gebelere göre yaşam kalitesi puan ortalamalarının daha düşük olduğu ve bu farkın istatistiksel olarak önemli olduğu bulunmuştur. Ayrıca araştırmada vaka grubundaki gebelerin gebelik uyumu puan ortalamalarının (33.21±5.89) kontrol grubundaki gebelere göre (27.13±3.84) daha yüksek olduğu ve yapılan istatistiksel analizde bu farkın önemli olduğu görülmüştür.Sonuç: Bu çalışmada, gebelikte reflü yaşayan gebelerin yaşam kalitesi ve gebeliğe uyum düzeylerinin gebelikte reflü yaşamayan gebelere göre daha düşük olduğu sonuçlarına ulaşılmıştır.