bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-border DCF valuation: discounting cash flows in foreign currency
Authors: Schüler Andreas 
Published: October 2020

AbstractThe paper seeks to develop a comprehensive framework to cross-border discounted cash flow valuation. Although the literature on company valuation and on international financial management is vast, such a framework has not yet been proposed. We build upon well-known fundamentals and relevant contributions, e.g. on the derivation of the risk-adjusted rate of return. Relevant risks are exchange rate risk, business risk, financial risk, the risk of the tax effects induced by debt financing, and the risk of default. Additional tax effects beyond the well-known tax shield on interest expenses must be considered. Risk discounts from cash flows and risk premia to be added to risk-free interest rates are derived according to the global capital asset pricing model. A conceptual choice occurs not only between the foreign currency and the home currency approach, but also regarding the estimation of future exchange rates. The paper shows how a valuation can be implemented with or without consideration of covariances between cash flows and rate of returns with exchange rates. It also derives the discount rates if forward exchange rates are applied. We discuss the consequences of assuming the uncovered interest parity to hold. We assume deterministic debt and apply the adjusted present value approach. In addition, we derive the RADR to be used in the flow to equity and weighted average cost of capital approach. The paper addresses not only the valuation of a foreign company, but also the valuation of a domestic company that generates cash flows in foreign currency and/or uses debt in foreign currency.
Climate Feedback: Wissenschaft kommentiert Journalismus und entwickelt Mehrsystemkompetenz
Authors: Walter Stefanie , Görlach Janne , Brüggemann Michael 
Published: October 2020

ZusammenfassungWissenschaft und Journalismus beruhen auf unterschiedlichen Logiken. Aus Sicht der Systemtheorie überrascht es also nicht, wenn WissenschaftlerInnen Wissenschaftsjournalismus kritisieren. Gleichzeitig wird aber auch eine Medialisierung von Wissenschaft postuliert. Demnach würde sich Wissenschaft zunehmend an Medienlogiken orientieren. Diese Studie prüft explorativ, welche Kriterien WissenschaftlerInnen bei der Beurteilung journalistischer Artikel heranziehen und welche Aspekte sie loben und kritisieren. Dazu werten wir die Kommentare auf dem Blog „Climate Feedback“ qualitativ inhaltsanalytisch aus. Induktiv werden zunächst die angelegten Evaluationskriterien der WissenschaftlerInnen kategorisiert und dann den Überkategorien „journalistische Vermittlungsleistung“ oder „wissenschaftliche Informationsleistung“ zugeordnet. Unsere Ergebnisse, basierend auf 82 Blogeinträgen und den Kommentaren von 184 WissenschaftlerInnen im Zeitraum von 2015 bis 2017, zeigen, dass sich die WissenschaftlerInnen intensiv und sogar häufiger mit Aspekten der journalistischen als der wissenschaftlichen Leistung beschäftigen. Sie sehen die journalistischen Kriterien eher als erfüllt an, während sie das Fehlen wissenschaftlicher Standards kritisieren. Die beteiligten WissenschaftlerInnen kombinieren die Kommunikationsnormen beider Systeme. Für den Ansatz der Medialisierung von Wissenschaft ergibt sich der Befund, dass die Diffusion von Medienlogiken keineswegs zur Aufgabe von Logiken der Wissenschaft führen muss, sondern dass kompetente Akteure an der Schnittstelle zwischen Journalismus und Wissenschaft Mehrsystemkompetenz erwerben und anwenden können.
Aronia melanocarpa Ameliorates Adrenal Cytoarchitecture Against the Hexavalent Chromium-Induced Injury
Authors: Savici Jelena , Cristina Romeo Teodor , Brezovan Diana , Radulov Isidora , Balta Cornel , Boldura Oana Maria , Muselin Florin 
Published: October 2020

AbstractHexavalent chromium is a toxin that penetrates the cell, triggering reactive oxygen species (ROS) production. Aronia melanocarpa, due to its proanthocyanidins, anthocyanins, and phenolic acid contents, is a valuable antioxidant. The aim was to observe the influence of hexavalent chromium Cr(VI) on the adrenal gland, and if this impact can be recovered by the administration of A. melanocarpa. Accordingly, 36 rats were divided into six groups: control; Aronia; Cr receiving Cr(VI) in distilled water for 3 months; CrA receiving a mix of Cr(VI) and A. melanocarpa at 2.5% aqueous extract for 3 months; Cr2 receiving, for 3 months, Cr(VI) in distilled water, and next, for 1 month, only distilled water; and respectively, CrA2 receiving, for 3 months, Cr(VI) in distilled water, followed by 1 month of Aronia at 2.5% extract administration. The adrenal gland samples were examined toward histological and molecular assessment, and results were statistically analyzed (ANOVA). Hexavalent chromium induced changes in the adrenal cortex expressed by focal or diffuse hypertrophies, cytoplasmic vacuolization (due to lipidic accumulation), and cells’ shape and size alteration, including necrosis. These structural alterations were carried by Bax and Bcl2 gene expression: the Bax gene expression levels, increased significantly (p < 0.001) in all experimental groups, except the Aronia group, compared with control. In the Cr2, CrA, and CrA2 groups, notable reduction of Bax gene expression (p < 0.001) was reported compared with the Cr group. Regarding the Bcl2 gene expression (p < 0.001), a significant increase was observed in the experimental groups, compared with the control. The Bcl2 expression level had a similar pattern to Bax gene, consequently trying to compensate its overexpression. Aronia administered concomitantly, or after Cr(VI), diminished structural changes and expression of the studied genes, thus reducing the Bax/Bcl2 ratio and suggesting that the active ingredients from Aronia are capable of blocking apoptotic cascade induced by the pathway of Bax and Bcl2 proteins.
Trustworthy artificial intelligence
Authors: Thiebes Scott , Lins Sebastian , Sunyaev Ali 
Published: October 2020

AbstractArtificial intelligence (AI) brings forth many opportunities to contribute to the wellbeing of individuals and the advancement of economies and societies, but also a variety of novel ethical, legal, social, and technological challenges. Trustworthy AI (TAI) bases on the idea that trust builds the foundation of societies, economies, and sustainable development, and that individuals, organizations, and societies will therefore only ever be able to realize the full potential of AI, if trust can be established in its development, deployment, and use. With this article we aim to introduce the concept of TAI and its five foundational principles (1) beneficence, (2) non-maleficence, (3) autonomy, (4) justice, and (5) explicability. We further draw on these five principles to develop a data-driven research framework for TAI and demonstrate its utility by delineating fruitful avenues for future research, particularly with regard to the distributed ledger technology-based realization of TAI.
Guest Editors’ Introduction to the Special Issue on “Recent Advances in Design and Analysis of Experiments and Observational Studies in Agriculture”
Authors: Piepho Hans-Peter , Tempelman Robert J. , Williams Emlyn R. 
Published: October 2020

AbstractThe Journal of Agricultural, Biological and Environment Statistics (JABES) special issue on Recent Advances in Design and Analysis of Experiments and Observational Studies in Agriculture covers a select set of topics currently of primary importance in the field. Efficient use of resources in agricultural research, as well as valid statistical inference, requires good designs, and this special issue boasts seven papers providing both review and cutting-edge methodology for the purpose. A broad range of methods for analysis of data arising in different branches agricultural research is covered in another five exciting papers. This special issue highlights the importance of and opportunities for applied statistics in agriculture.
Two oat genotypes with different field resistance to Fusarium head blight respond similarly to the infection at spikelet level
Authors: Hautsalo Juho , Latvala Satu , Manninen Outi , Haapalainen Minna , Hannukkala Asko , Jalli Marja 
Published: October 2020

AbstractCultivar resistance is essential for the management of Fusarium head blight (FHB) disease in oat production. However, the breeders lack methods suitable for phenotyping disease resistance and resistance sources. In this paper we compared two oat genotypes, a rejected variety BOR31 and a landrace VIR7766, with four different traits that could reflect resistance to FHB in a greenhouse environment. Spray and point inoculations were used to inoculate Fusarium graminearum into flowering oat plants. When spray-inoculated, VIR7766 was significantly more resistant against the initial infection than BOR31, measured by the number of Fusarium-infected kernels and by DON accumulation. In the point-inoculated oats, the loss of fresh weight in the inoculated spikelet correlated well with the increasing F. graminearum biomass in the spikelet, measured six days after inoculation. However, no difference in the growth of the fungus was observed between the tested oat genotypes by point inoculation. We speculate that once the infection is established, the ability of the oat plant to resist the spread of the infection within a spikelet is low in the genotypes studied, although oat, in general, due to its panicle structure, is considered to have a high resistance against Fusarium infection.
Lung Ultrasound Findings in Patients with COVID-19
Authors: Marggrander Daniel T. , Borgans Frauke , Jacobi Volkmar , Neb Holger , Wolf Timo 
Published: October 2020

AbstractThe current SARS-CoV-2 outbreak leads to a growing need of point-of-care thoracic imaging that is compatible with isolation settings and infection prevention precautions. We retrospectively reviewed 17 COVID-19 patients who received point-of-care lung ultrasound imaging in our isolation unit. Lung ultrasound was able to detect interstitial lung disease effectively; severe cases showed bilaterally distributed B-Lines with or without consolidations; one case showed bilateral pleural plaques. Corresponding to CT scans, interstitial involvement is accurately depicted as B-Lines on lung ultrasound. Lung ultrasound might be suitable for detecting interstitial involvement in a bedside setting under high security isolation precautions.
The Mortal Coil of Covid-19, Fake News, and Negative Epistemic Postdigital Inculcation
Authors: Rose Jennifer 
Published: October 2020

AbstractThe Covid-19 pandemic has engendered turmoil around our globe, rendering an urgent need for accurate, truthful information as a life-saving resource for humanity. However, coinciding with this global, deadly pandemic is the proliferation of fake news. While pandemics and fake news are not new phenomena, an unprecedented time in history is presently unfolding when considered with the postdigital era. Digital media enables the prolific repetitious spread of fake news during crises when accurate and truthful information is necessary. Consequently, the ability of humans to discern between fact and fiction diminishes. It has resulted in some people making life-ending decisions based on their exposure to fake news. In this article, I define a primarily ignored and invisible epistemological process at work: negative epistemic postdigital inculcation, that, while has been at work with the rise of modern digital media, has primarily become visible because of the interrelationships between implicit learning, Covid-19, fake news, and digital media. While the inculcation outlined in this paper occurs mostly outside of our awareness, I discuss a role for education in helping reduce the ensuing mortal coil of fake news.
Dysglycaemia and South Asian ethnicity: a proteomic discovery and confirmation analysis highlights differences in ZAG
Authors: Pearsey Harriet M. , Henson Joseph , Sargeant Jack A. , Webb David , Gill Jason M. R. , Celis-Morales Carlos , Suzuki Toru , Waller Helen , Khunti Kamlesh , Ng Leong L. , Bowden-Davies Kelly A. , Cuthbertson Daniel J. , Jackson Andrew , Davies Melanie J. , Yates Thomas 
Published: October 2020

Abstract
Aims
To (1) explore and verify differences in the plasma proteome of white European (WE) and South Asian (SA) adults with normal glycaemic control (NGC) or non-diabetic hyperglycaemia (NDH) and to (2) validate these findings using a separate WE and SA cohort at a high risk of NDH.

Methods
Mass spectrometry analysis was performed on fasted samples from 72 WE or SA men with NGC or NDH. These results were verified using specific biochemical assays and validated by repeating the analysis in an additional cohort of 30 WE and 30 SA adults. Proteomic results were analysed using independent samples t test and univariate analysis. The targeted assay results were analysed using generalised linear models with adjustment for appropriate covariates including age, BMI, fasting plasma glucose, high-density lipoprotein-cholesterol, triglycerides and sex.

Results
Only zinc-alpha-2-glycoprotein (ZAG) significantly differed between both ethnicities and glycaemic control groups. ZAG-specific biochemical assays verified the lower circulating ZAG in SAs (41.09 versus 37.07 (mg L−1); p = 0.014), but not the difference between NGC and NDH groups (p = 0.539). Validation of the ethnicity difference in a separate cohort confirmed that, after adjustment for covariates, ZAG was lower in SAs (p = 0.018). There was no association between ZAG and glycaemic control in the validation cohort.

Conclusions
Our analyses identified that ZAG is lower in SAs compared to WEs, but its difference between glycaemic control statuses was uncertain. Further research is needed to establish whether lower ZAG in SAs is associated with, or prognostic of, health outcomes, particularly regarding the risk of dysglycaemia.
Quantifying gender norm resistance
Authors: Nielson Matthew G. , Martin Carol Lynn , Rogers Leoandra Onnie , Miller Cindy Faith , England Dawn 
Published: October 2020

ABSTRACTIntroductionQualitative and mixed‐methods researchers have described the experience of gender norm resistance in adolescence and identified potential types of resistance including indirect resistance (motivated by a preference for gender‐atypicality) and direct resistance (motivated by dislike of gender norms and a desire to change them). Building on this work, we developed the Gender Norm Resistance measure to operationalize indirect and direct gender norm resistance. We explored how gender norm resistance aligns with and differs from other gender self‐concepts (e.g., felt pressure to conform to gender norms) and peer relations (e.g., contact with peers) and tested for gender differences.MethodsParticipants included 484 early adolescents (girls = 234; Mage = 11.44 years, SD = 0.56). Analyses included factor analyses (EFA, CFA) and bivariate correlations to gather validity evidence, and ANOVAs to determine mean level differences.ResultsEvidence that validated using the proposed measure as intended was found including confirmation of the two types of gender norm resistance (indirect and direct). Mean differences were found across participant gender as well as across types of gender norm resistance.ConclusionsThe findings highlight the strengths and weaknesses of the Gender Norm Resistance measure, the different ways adolescents experience indirect and direct gender norm resistance, and the limited role of felt pressure in gender norm resistance.
Multinational Corporations and the Politics of International Trade in Multidisciplinary Perspective
Authors: Ballor Grace A. , Yildirim Aydin B. 
Published: October 2020

AbstractFrom the technical analyses of wide ranges of scholars to the public discourse backlashes against globalization, there is a huge volume of work historicizing, quantifying, and problematizing the complex role of multinational corporations (MNCs) in international trade. The body of literature is so large that most readers rely on disciplinary boundaries to narrow the catalog, causing them to miss out on important synergies across fields. By bringing the work of historians, lawyers, and political scientists working on MNCs and international trade into conversation, we offer an expanded perspective. Our collective contribution highlights the political dimensions of MNCs within the frameworks of global economic governance, in which corporations seek to influence trade policies amid rising protectionism and coordinate their activities within industry associations while regulators struggle to hold MNC parent companies accountable to international human rights violations across their value chains. Especially in this moment of re-evaluation — and possible de-globalization following the shock of COVID-19 — our multidisciplinary analysis explains how MNCs exerted political power over trade regimes in the past, by what means they seek to shape regulatory frameworks in the present, and what the possible futures might be for big business operations in a more or less global economy.
Epistemic Dependence and Oppression: A Telling Relationship
Authors: Sertler Ezgi 
Published: October 2020

AbstractEpistemic dependence refers to our social mechanisms of reliance in practices of knowledge production. Epistemic oppression concerns persistent and unwarranted exclusions from those practices. This article examines the relationship between these two frameworks and demonstrates that attending to their relationship is a fruitful practice for applied epistemology. Paying attention to relations of epistemic dependence and how exclusive they are can help us track epistemically oppressive practices. In order to show this, I introduce a taxonomy of epistemic dependence (interpersonal – communal – structural). I argue that this particular taxonomy is useful for tracking epistemically oppressive practices in institutional contexts. This is because, first, the forms of epistemic dependence in this taxonomy yield, what I call,diagnostic questions.These are questions that help us track how relations of epistemic dependence could become exclusive and that thus help reveal epistemic oppression in institutional contexts. Second, the forms of epistemic dependence in the taxonomy are interrelated. Paying attention not just to each of three forms of epistemic dependence but also to the way in which they are interrelated is useful for illuminating epistemically oppressive practices. I conclude by demonstrating how the diagnostic questions can be used in analyses of concrete institutional practices in asylum law and higher education.
Impact of California’s mandate for antimicrobial stewardship programs on rates of methicillin-resistant Staphylococcus aureus and Clostridioides difficile infection in acute-care hospitals
Authors: Garcia Reeves Alessandra B. , Stearns Sally C. , Trogdon Justin G. , Lewis James W. , Weber David J. , Weinberger Morris 
Published: October 2020

AbstractObjective:To estimate the impact of California’s antimicrobial stewardship program (ASP) mandate on methicillin-resistant Staphylococcus aureus (MRSA) and Clostridioides difficile infection (CDI) rates in acute-care hospitals.Population:Centers for Medicare and Medicaid Services (CMS)–certified acute-care hospitals in the United States.Data Sources:2013–2017 data from the CMS Hospital Compare, Provider of Service File and Medicare Cost Reports.Methods:Difference-in-difference model with hospital fixed effects to compare California with all other states before and after the ASP mandate. We considered were standardized infection ratios (SIRs) for MRSA and CDI as the outcomes. We analyzed the following time-variant covariates: medical school affiliation, bed count, quality accreditation, number of changes in ownership, compliance with CMS requirements, % intensive care unit beds, average length of stay, patient safety index, and 30-day readmission rate.Results:In 2013, California hospitals had an average MRSA SIR of 0.79 versus 0.94 in other states, and an average CDI SIR of 1.01 versus 0.77 in other states. California hospitals had increases (P < .05) of 23%, 30%, and 20% in their MRSA SIRs in 2015, 2016, and 2017, respectively. California hospitals were associated with a 20% (P < .001) decrease in the CDI SIR only in 2017.Conclusions:The mandate was associated with a decrease in CDI SIR and an increase in MRSA SIR.
Carbon stocks and the use of shade trees in different coffee growing systems in the Peruvian Amazon
Authors: Solis R. , Vallejos-Torres G. , Arévalo L. , Marín-Díaz J. , Ñique-Alvarez M. , Engedal T. , Bruun T.B. 
Published: October 2020

AbstractAgroforestry systems can play an important role in mitigating the effects of climate change given their capacity to increase tree diversity and to store more carbon than conventional farming. This study aims at assessing carbon stocks and the use of shade trees in different coffee growing systems in the Northeast Peruvian Amazon. Carbon stocks in trees were estimated by field-based measurements and allometric equations. Carbon stocks in dead wood, litter and soil (upper 60 cm) were determined using field sampling and laboratory analysis. The diversity analysis drew on the Shannon–Weiner diversity index, and focus groups were used to obtain information about the local use of shade trees. The total carbon stock in the polyculture-shaded coffee system was 189 t C/ha, while the Inga-shaded and unshaded systems totalled 146 and 113 t C/ha, respectively. The soil compartment contributed the largest carbon stock in the coffee growing systems and contained 67, 82 and 96% of the total carbon stock in the polyculture-shaded, Inga-shaded and unshaded coffee systems, respectively. The Shannon–Weiner index and tree species richness values were highest for the polyculture-shaded coffee system, with a total of 18 tree species identified as important sources of fodder, food, wood, firewood and medicine. Therefore, coffee agroforestry systems play a significant role in carbon storage, while promoting conservation of useful trees in agricultural landscapes in the Peruvian Amazon.
A rise in facial nerve palsies during the coronavirus disease 2019 pandemic
Authors: Zammit M , Markey A , Webb C 
Published: October 2020

AbstractObjectiveAn increase in spontaneous lower motor neuron facial nerve (VIIth cranial nerve) palsies was seen during the severe acute respiratory syndrome coronavirus 2 outbreak in our emergency clinic. This led us to perform a single-centre cohort review.MethodsA retrospective review was conducted of VIIth cranial nerve palsies from January to June 2020 and the findings were compared to those cases reviewed in the previous year. The severe acute respiratory syndrome coronavirus 2 incidence of the cohort was compared with that of the Liverpool population.ResultsOur VIIth cranial nerve palsy incidence in the 2020 period was 3.5 per cent (30 out of 852), 2.7 higher than last year's rate of 1.3 per cent (14 out of 1081), which was a statistically significant difference (p < 0.01). Two of the 17 patients in our cohort tested positive for severe acute respiratory syndrome coronavirus 2 (11.8 per cent), contrasting with Liverpool's severe acute respiratory syndrome coronavirus 2 incidence (0.5 per cent).ConclusionSevere acute respiratory syndrome coronavirus 2 may be responsible for an increased number of facial nerve palsies; it is important for clinicians to be aware that this may being an initial presentation of the disease.