bluuebunny/crossref_metadata_2025_split huggingface dataset:
Injectable Polypeptide‐Protein Hydrogels for Promoting Infected Wound Healing
Authors: Cheng Liang , Cai Zhengwei , Ye Tingjun , Yu Xiaohua , Chen Zhijie , Yan Yufei , Qi Jin , Wang Lei , Liu Zhihong , Cui Wenguo , Deng Lianfu 
Published: May 2020

AbstractProtein is the key composition of all tissues, which has also been widely used in tissue engineering due to its superior biocompatibility and low immunogenicity. However, natural protein usually lacks active functions such as vascularization, osteo‐induction, and neural differentiation, which limits its further applications as a functional biomaterial. Here, based on the mimetic extracellular matrix feature of bovine serum albumin, injectable polypeptide‐protein hydrogels with vascularization and antibacterial abilities are constructed successfully via coordinative cross‐linking of sulfydryl groups with silver ions (Ag+) for the regeneration of infected wound. In this protein hydrogel system, (Ag+), acting as crosslinkers, can not only provide a sterile microenvironment and a strong and robust antibacterial ability but also introduce K2(SL)6K2 (KK) polypeptide, which endows the hydrogel with vascularization behavior. Furthermore, the in vivo data show that the polypeptide‐protein hydrogel has a considerable collagen deposition and vascularization abilities in the early stage of wound healing, resulting in rapid new tissue regeneration featured with newly appeared hair follicles. Altogether, this newly developed multifunctional 3D polypeptide‐protein hydrogel with vascularization, antibacterial properties, and hair follicle promotion can be a promising approach in biomedical fields such as infected wound healing.
Inkjet‐Printed Wearable Nanosystems for Self‐Powered Technologies
Authors: Huang Tao‐Tse , Wu Wenzhuo 
Published: May 2020

AbstractThe scalable production of nanomaterials‐based electronic components with mechanically compliable form factors not only provides interesting research topics but also ushers in exciting opportunities for wearable applications in consumer electronics, healthcare, human–machine interface, etc. Wearable nanosystems consist of components such as thin‐film transistors, flexible sensors, energy harvesters, and energy storage devices. Despite the increased interests and efforts in nanotechnology‐enabled wearables, reducing the manufacturing and assembly costs while improving the performance at the device and system level remains a major technological challenge. The inkjet printing process has emerged as a potential economic method for nanomanufacturing functional devices. Here, the authors review the recent advances in inkjet‐printed wearable nanodevices and provide an in‐depth discussion focusing on the materials, manufacturing process, integration, performance issues, and potential applications for inkjet‐printed self‐powered wearable devices. The authors compile a comprehensive list of the reported flexible devices with the corresponding materials employed. Finally, they discuss the challenges and opportunities associated with related topics.
Toward an All‐Ceramic Cathode–Electrolyte Interface with Low‐Temperature Pressed NASICON Li1.5Al0.5Ge1.5(PO4)3 Electrolyte
Authors: Paolella Andrea , Zhu Wen , Bertoni Giovanni , Perea Alexis , Demers Hendrix , Savoie Sylvio , Girard Gabriel , Delaporte Nicolas , Guerfi Abdelbast , Rumpel Matthias , Lorrmann Henning , Demopoulos George P. , Zaghib Karim 
Published: May 2020

AbstractThis work shows, for the first time, the critical influence of pressure during the hot sintering stage on the ionic conductivity of the lithium super ionic conductor Li1.5Al0.5Ge1.5(PO4)3. A hot press method is developed to obtain high ionic conductivities at the significantly decreased densification temperature of only 650 °C by applying pressure (56 MPa). Considering the possible initiation of undesirable decomposition reactions when cathode materials are annealed at high temperature (typically ≥700 °C), the use of high pressure at 650 °C can significantly limit the formation of degradation by‐products. This study determines the criteria required to optimize the pressure and temperature parameters for enhancing the total ionic conductivity. Finally, this study reports an all solid‐state battery based on a LiFePO4 olivine cathode prepared at 650 °C showing very good Li‐intercalation/deintercalation performance. Good ionic interfacial contact is achieved without using polymer and liquid electrolyte.
Ultraviolet Light‐Assisted Electrospinning of Core–Shell Fully Cross‐Linked P(NIPAAm‐co‐NIPMAAm) Hydrogel‐Based Nanofibers for Thermally Induced Drug Delivery Self‐Regulation
Authors: Pawłowska Sylwia , Rinoldi Chiara , Nakielski Paweł , Ziai Yasamin , Urbanek Olga , Li Xiaoran , Kowalewski Tomasz Aleksander , Ding Bin , Pierini Filippo 
Published: May 2020

AbstractBody tissues and organs have complex functions which undergo intrinsic changes during medical treatments. For the development of ideal drug delivery systems, understanding the biological tissue activities is necessary to be able to design materials capable of changing their properties over time, on the basis of the patient's tissue needs. In this study, a nanofibrous thermal‐responsive drug delivery system is developed. The thermo‐responsivity of the system makes it possible to self‐regulate the release of bioactive molecules, while reducing the drug delivery at early stages, thus avoiding high concentrations of drugs which may be toxic for healthy cells. A co‐axial electrospinning technique is used to fabricate core–shell cross‐linked copolymer poly(N‐isopropylacrylamide‐co‐N‐isopropylmethacrylamide) (P(NIPAAm‐co‐NIPMAAm)) hydrogel‐based nanofibers. The obtained nanofibers are made of a core of thermo‐responsive hydrogel containing a drug model, while the outer shell is made of poly‐l‐lactide‐co‐caprolactone (PLCL). The custom‐made electrospinning apparatus enables the in situ cross‐linking of P(NIPAAm‐co‐NIPMAAm) hydrogel into a nanoscale confined space, which improves the electrospun nanofiber drug dosing process, by reducing its provision and allowing a self‐regulated release control. The mechanism of the temperature‐induced release control is studied in depth, and it is shown that the system is a promising candidate as a “smart” drug delivery platform.
A Red‐Emissive Fluorescent Probe with a Compact Single‐Benzene‐Based Skeleton for Cell Imaging of Lipid Droplets
Authors: Zhou Ri , Cui Yuanyuan , Dai Jianan , Wang Chenguang , Liang Xishuang , Yan Xu , Liu Fangmeng , Liu Xiaomin , Sun Peng , Zhang Hongyu , Wang Yue , Lu Geyu 
Published: May 2020

AbstractLipid droplets (LDs) are important organelles associated with many physiological processes as well as diseases. To visualize LDs and study their versatile functions, the fluorescence imaging technique is one of the most powerful tools. Thus, the development of fluorescent probes for LDs imaging has attracted increased attention in recent years. Herein, a new LDs fluorescent probe Ph‐Red is developed and its application in fluorescence imaging is carefully demonstrated. The probe Ph‐Red has a compact single‐benzene‐based molecular structure and can be easily synthesized via a one‐step reaction. Impressively, the probe displays strong red emission based on a very small π‐system consisting of only one benzene ring. Moreover, the probe shows high LDs staining selectivity and good cellular viability, and is tolerant for repeatedly fluorescence imaging. Given these advantages, the 3D confocal imaging in fixed cells as well as multicolor confocal imaging in live cells are successfully realized, highlighting the utility of the single‐benzene‐based fluorescent probe Ph‐Red for LDs imaging. In addition, the hydrophobicity of the probe and the molecular size are revealed to play critical roles for efficiently staining LDs, which are important insights for the development of new LDs fluorescent probes.
Wearable Conformal Metasurfaces for Polarization Division Multiplexing
Authors: Li Jiaqi , Zhang Lei , Zhang Min , Su Hong , Li Irene Ling , Ruan Shuangchen , Liang Huawei 
Published: May 2020

AbstractIn practice, there is a strong requirement for modulating the performance of existing bulk devices without changing their physical geometry. In this study, by attaching a flexible metasurface on a cylindrical lens, a wearable conformal metasurface for terahertz polarization division multiplexing is demonstrated, which could be used in wireless communications, detection, and imaging. The integrated metasurface/lens can achieve the control functions of spot focusing, generation of Bessel beams, and phase holograms, respectively, for crosspolarized waves and line focusing for copolarized waves. A total modulation efficiency of up to 87% is experimentally obtained. Notably, the metasurfaces can be attached on/removed from existing bulk devices multiple times, without reducing the performances of both metasurface and conventional devices. As the flexible samples are fabricated using the cost‐effective standard flexible printed circuit technique, a multilayer conformal metasurface can be easily obtained for an efficient control. Furthermore, the same bulk device can be integrated with different flexible metasurfaces for various controls. Thus, the proposed metasurface can provide a promising flexible platform for various integrated applications and contribute to the development of wearable functional devices.
Soft Photonic Fibers for Colorimetric Solvent Vapor Sensing
Authors: Malekovic Mirela , Urann Markus , Steiner Ullrich , Wilts Bodo D. , Kolle Mathias 
Published: May 2020

AbstractStimuli‐responsive elastomers are promising material systems for the development of optical sensors with visual outputs that can be easily assessed by the human eye. These materials, when shaped into alternating layers, form distributed Bragg reflectors (DBRs) that feature a high spectrally selective reflectivity. The adsorption of vapor molecules into these photonic structures leads to partial swelling in the constituent materials that can induce pronounced color changes. Here, it is demonstrated that soft photonic fibers with a DBR‐cladding can selectively sense and quantify different organic vapors. It is found that fibers with a multilayer cladding assembled of films of polydimethylsiloxane (PDMS) and a polystyrene‐polyisoprene block‐copolymer (PSPI) change color sensitively depending on the concentration of toluene, benzene, tetrahydrofuran, or chloroform vapors. It is shown that this is a direct consequence of a selective swelling of the constituent polymer layers due to vapor adsorption. With wavelength variations as small as 5 nm being noticeable to the human eye, such photonic fibers are interesting materials for optical sensors. Modifications of their building blocks and their structural morphology make these vapor‐sensing fibers a versatile platform for standalone and textile‐integrated solvent sensing systems applied in industrial and lab‐scale manufacturing processes.
Surface Engineered Hybrid Core–Shell Si‐Nanowires for Efficient and Stable Broadband Photodetectors
Authors: Sarkar Krishnendu , Devi Pooja , Lata Akash , Lokku Vinod K. , Kumar Praveen 
Published: May 2020

AbstractSilicon nanostructures have gained intensive interest to develop broadband photodetectors at a large‐scale due to their excellent electronic properties. Herein, Si‐nanowires (SiNWs) decorated with reduced graphene oxide:carbon quantum dots (rGO:CQDs) nanocomposite (NC), as core–shell heterojunction building blocks for broadband (ultraviolet (UV)–near infrared (NIR)) photodetectors (PDs), are demonstrated. The SiNWs and CQDs are synthesized by wet‐chemical etching and facile pyrolysis methods, respectively. Photogenerated carriers are transported through rGO because of its high electron mobility and favorable band alignment with CQDs and Si. Further, to minimize the recombination of photogenerated carriers, and enhance the response in the visible region, plasmon‐enhanced AuCQDs are incorporated in the shell matrix. The optimized heterostructure (rGO:AuCQDs/undoped CQDs/SiNWs) is sensitive to a broad wavelength range covering the UV to NIR (360 to 940 nm) region, manifests the excellent responsivity of 16 A W−1 at 360 nm, detectivity (D*) of 2.2 × 1013 Jones, and noise equivalent power as low as 2.8 fW Hz−1/2. The optimized PDs heterostructure demonstrates excellent air‐stability after 8 days of illumination without any encapsulation or protective coating. The proposed simple, cost‐effective, and Si‐process‐line compatible fabrication of Si‐based PD device structure imposes a great promise for highly efficient and stable advanced futuristic optoelectronic devices.
Work Function Evolution in Li Anode Processing
Authors: Etxebarria Ane , Koch Stephan L. , Bondarchuk Oleksandr , Passerini Stefano , Teobaldi Gilberto , Muñoz‐Márquez Miguel Ángel 
Published: May 2020

AbstractToward improved understanding and control of the interactions of Li metal anodes with their processing environments, a combined X‐ray photoelectron spectroscopy (XPS), ultraviolet photoelectron spectroscopy (UPS), and density functional theory (DFT) characterization of the effects that O2, CO2, and N2, the main gases in dry‐atmosphere battery production lines, induced on a reproducibly clean Li surface at room temperature is presented here. XPS measurements demonstrate that O2 is ten times more effective than CO2 at oxidizing metal Li. Notably, pure N2 is shown to not dissociate on clean metal Li. UPS results indicate that decomposition of O2 (CO2) reduces the work function of the Li surface by almost 1 eV, therefore increasing the reduction energy drive for the treated substrate by comparison to bare metallic Li. DFT simulations semiquantitatively account for these results on the basis of the effects of dissociative gas adsorption on the surface dipole density of the Li surface.
High‐Voltage‐Driven Surface Structuring and Electrochemical Stabilization of Ni‐Rich Layered Cathode Materials for Li Rechargeable Batteries
Authors: Song Seok Hyun , Cho Moses , Park Inchul , Yoo Jong‐Gyu , Ko Kyung‐Tae , Hong Jihyun , Kim Jongsoon , Jung Sung‐Kyun , Avdeev Maxim , Ji Sungdae , Lee Seongsu , Bang Joona , Kim Hyungsub 
Published: May 2020

AbstractLayered lithium–nickel–cobalt–manganese oxide (NCM) materials have emerged as promising alternative cathode materials owing to their high energy density and electrochemical stability. Although high reversible capacity has been achieved for Ni‐rich NCM materials when charged beyond 4.2 V versus Li+/Li, full lithium utilization is hindered by the pronounced structural degradation and electrolyte decomposition. Herein, the unexpected realization of sustained working voltage as well as improved electrochemical performance upon electrochemical cycling at a high operating voltage of 4.9 V in the Ni‐rich NCM LiNi0.895Co0.085Mn0.02O2 is presented. The improved electrochemical performance at a high working voltage at 4.9 V is attributed to the removal of the resistive Ni2+O rock‐salt surface layer, which stabilizes the voltage profile and improves retention of the energy density during electrochemical cycling. The manifestation of the layered Ni2+O rock‐salt phase along with the structural evolution related to the metal dissolution are probed using in situ X‐ray diffraction, neutron diffraction, transmission electron microscopy, and X‐ray absorption spectroscopy. The findings help unravel the structural complexities associated with high working voltages and offer insight for the design of advanced battery materials, enabling the realization of fully reversible lithium extraction in Ni‐rich NCM materials.
Nature of Novel 2D van der Waals Heterostructures for Superior Potassium Ion Batteries
Authors: Wang Jue , Wang Bin , Lu Bingan 
Published: May 2020

AbstractNovel 2D van der Waals heterostructures with innovative bimetallic oxychloride (Bi‐ and Sb‐based oxychloride) nanosheets that are well dispersed on reduced graphene oxide nanosheets, are established through element engineering for superior potassium ion battery (PIBs) anodes. This material displays an exceptional electrochemical performance, obtaining a discharge capacity as high as 360 mAh g−1 at 100 mA g−1 after running 1000 cycles for over 9 months with a capacity preservation percentage of 88.5% and achieving a discharge capacity as high as 319 mAh g−1 at 1000 mA g−1, in addition to the low charge/discharge plateaus for anodes and promising full cell performance. More significantly, the nature of such 2D van der Waals heterostructures, including the element engineering for morphology control, the function of each component of heterostructures, the mechanism of potassium ion storage, and the process of K+ intercalation accompanied with the lattice distortion and chemical bond breakages, is explored in depth. This study is critical for not only paving the way for the practical application of PIBs but also shedding light on fundamentals of potassium ion storage in 2D van der Waals heterostructures.
Sulfonate N‐Heterocyclic Carbene–Copper Complexes: Uniquely Effective Catalysts for Enantioselective Synthesis of C−C, C−B, C−H, and C−Si Bonds
Authors: Hoveyda Amir H. , Zhou Yuebiao , Shi Ying , Brown M. Kevin , Wu Hao , Torker Sebastian 
Published: May 2020

AbstractA copper‐based complex that contains a sulfonate N‐heterocyclic carbene ligand was first reported 15 years ago. Since then, these organometallic entities have proven to be uniquely effective in catalyzing an assortment of enantioselective transformations, including allylic substitutions, conjugate additions, proto‐boryl additions to alkenes, boryl and silyl substitutions, hydride‐allyl additions to alkenyl boronates, and additions of boron‐containing allyl moieties to N‐H ketimines. In this review article, we detail the shortcomings in the state‐of‐the‐art that fueled the development of this air stable ligand class, members of which can be prepared on multigram scale. For each reaction type, when relevant, the prior art at the time of the advance involving sulfonate NHC‐Cu catalysts and/or subsequent key developments are briefly analyzed, and the relevance of the advance to efficient and enantioselective total or formal synthesis of biologically active molecules is underscored. Mechanistic analysis of the structural attributes of sulfonate NHC‐Cu catalysts that are responsible for their ability to facilitate transformations with high efficiency as well as regio‐ and enantioselectivity are detailed. This review contains several formerly undisclosed methodological advances and mechanistic analyses, the latter of which constitute a revision of previously reported proposals.
Effect of silanol on the thermal stability of poly[methyl(trifluoropropyl)siloxane]
Authors: You Yang , Chen Jianding , Zheng Anna , Wei Dafu , Xu Xiang , Guan Yong 
Published: May 2020

AbstractPoly[methyl(trifluoropropyl)siloxane] (PMTFPS), which is an essential polymer in oil‐resistant rubber materials, exhibits unsatisfactory thermal stability. In this article, PMTFPSs with methyl and hydroxyl terminal groups are prepared, and their thermal stabilities are investigated via thermogravimetric analysis and pyrolysis‐gas chromatography‐mass spectrometry in an inert atmosphere. Additionally, the degradation mechanisms are discussed in terms of molecular structural characteristics (bond length and bond angle) and reaction driven forces (electrostatic potential and atom charge) based on quantum chemistry calculations. PMTFPS is found to degrade mainly into cyclic monomers through (a) the SiO rearrangement reaction in the middle of the chain and (b) the “back‐biting” reaction from the end of the chain. PMTFPS with silanol terminal groups is more likely to degrade according to pathway (b), resulting in more cyclotrisiloxane. Furthermore, the silanol from nano‐silica accelerates the degradation of PMTFPS, and the mechanism of this process is presented.
Effect of microsurgical varicocelectomy on semen parameters, serum, and intratesticular testosterone levels
Authors: Lima Thiago Fernandes Negris , Frech Fabio Stefano , Patel Premal , Blachman‐Braun Ruben , Ramasamy Ranjith 
Published: May 2020

AbstractObjectiveThe goal of this work was to evaluate if men who underwent microsurgical varicocelectomy would have improvement in serum testosterone (T) as well as serum 17‐hydroxyprogesterone (17‐OHP—An intratesticular T biomarker) in addition to semen parameters after operation.Materials and MethodsWe conducted a prospective analysis of 30 men who underwent microsurgical varicocelectomy from December 2018 to September 2019. We assessed varicocele grade and laterality, serum T, serum 17‐OHP, serum follicle‐stimulating hormone (FSH), serum LH, and semen parameters in baseline and follow‐up. According to the data distribution, we reported the median and interquartile ranges and utilized the Mann‐Whitney U, Student's t test and Wilcoxon rank test. Correlation analysis was performed with the Spearman test.ResultsIn the baseline, 9 (30%) men had 17‐OHP < 55 ng/dL and 21 (70%) men presented with 17‐OHP ≥ 55 ng/dL. Also, 19 men had TMSC < 9 million, including 6 men with azoospermia, 1 man with cryptozoospermia, and 11 men with TMSC ≥ 9 million. We found an improvement in most SA parameters of most men, which include concentration (63.3%, 19/30), motility (46.6%, 14/30), and TMSC (60%, 18/30). About seven (36.8%) men had TMSC upgraded to > 9. There was a significant change in volume (2.1 [1.5‐2.8] to 2.4 [1.7‐3.6] cc, P = .018), concentration (6.8 [0.8‐22.5] to 12.5 [1‐31] million/cc, P = .047) and TMSC (4.4 [0.3‐15.1] to 10.5 [0‐41.8] million, P = .012) after surgery. We neither found a change in serum T nor a change in intratesticular T (serum 17‐OHP) after varicocelectomy (P > .05). FSH, LH and T were similar both before and after varicocelectomy (P > .05).ConclusionDespite improvement in semen parameters following varicocelectomy, we did not see changes in either serum or intratesticular T. This suggests that improvement of semen parameters following varicocele repair could be from factors other than changes in androgen levels within the testis.
The Fluidity of the Bacterial Outer Membrane Is Species Specific
Authors: Cao Pengbo , Wall Daniel 
Published: May 2020

AbstractThe outer membrane (OM) is an essential barrier that guards Gram‐negative bacteria from diverse environmental insults. Besides functioning as a chemical gatekeeper, the OM also contributes towards the strength and stiffness of cells and allows them to sustain mechanical stress. Largely influenced by studies of Escherichia coli, the OM is viewed as a rigid barrier where OM proteins and lipopolysaccharides display restricted mobility. Here the discussion is extended to other bacterial species, with a focus on Myxococcus xanthus. In contrast to the rigid OM paradigm, myxobacteria possess a relatively fluid OM. It is concluded that the fluidity of the OM varies across environmental species, which is likely linked to their evolution and adaptation to specific ecological niches. Importantly, a fluid OM can endow bacteria with distinct functions for cell‐cell and cell‐environment interactions.
Novel homozygous variant in WISP3 in a family with unrecognized progressive pseudorheumatoid dysplasia
Authors: Patel Chandreshkumar , Khanshour Anas M. , Wilkes David , Rios Jonathan J. , Sheff Kelly W. , Nassi Lorien , Wise Carol A. 
Published: May 2020

AbstractWe present the use of whole‐genome sequencing to correctly diagnose progressive pseudorheumatoid dysplasia in patients with atypical clinical and radiologic findings and prior diagnosis of juvenile idiopathic arthritis.