bluuebunny/crossref_metadata_2025_split huggingface dataset:
APPROACHES TO THE DEVELOPMENT AND IMPLEMENTATION OF CLINICAL AND ORGANIZATIONAL REGULATIONS FOR MEDICAL CARE OF PATIENTS WITH SYPMPOMS OF SUSPECTED CORONAVIRUS DISEASE (COVID-19)
Authors: Dyachuk Dmitro D. , Zyukov Oleg L. , Oshyvalova Olena O. , Vovk Lidiia M. , Naumenko Oleksandr V. , Melnyk Nataliia Y. , Simak Igor M. , Chernii Tatiana V. , Biloshytska Oksana K. 
Published: June 2020

Resume. Standardization occupies a leading position in the system of tools of quality management in health care. The urgency of counteracting the spread of coronavirus disease (COVID-19) poses a task for health professionals to develop a standard of medical care.
The aim of the study. Development and implementation of a clinical route for a patient with acute respiratory syndrome, identified case of coronavirus disease (COVID-19) for health care facilities.
Material and methods. The State Scientific Institution "Scientific and Practical Center for Preventive and Clinical Medicine" of the State Administration has formed a clinical route of the patient in accordance with current legislation of Ukraine and modern scientific literary sources on relevant issues of coronavirus disease (COVID-19)prevention.
Results. The patient's clinical route is presented on 127 pages, which includes the organization of provision of medical care, a description of outpatient activities, emergency care, hospital care, 29 appendices, 10 flowcharts, 11 instructions and registers.
Conclusions.The clinical route of a patient with acute respiratory syndrome, identified case of coronavirus disease (COVID-19) is a new clinical and organizational document that is clinical managementtoolthat manages updates in accordance with current scientific developments and underpins an integrated approach to healthcare.
TO THE QUESTION OF ORGANISATION SCHOOL FEEDING
Authors: Merkulova T.V. , Peresypkina T.V. , Avdiievska O.H. , Cherniakova H.M. 
Published: June 2020

Along with physical activity and psycho-emotional status, nutrition is one of the most important indicators of the quality of life, which affect the human body from the moment of birth to the last moments of life. The problem of inadequate nutrition and alimentary-dependent diseases is especially acute in school age. According to official statistical data diseases of the digestive system occupy a leading place among schoolchildren in all age categories.
Aim. Assessment of the prevalence of digestive diseases among schoolchildren, determination of the features of catering in educational institutions, study of the nutritional behavior of modern schoolchildren.
Materials and methods. Determining the structure of pathological lesions of schoolchildren according to the "Center for Medical Statistics of the Ministry of Health of Ukraine". Questioning of 588 parents of elementary school students of two schools in Kharkov on the nutritional behavior of children.
Results and discussion. According to official statistics in 2017 digestive diseases occupy the second ranking place among schoolchildren (7.9% among children 7-14 years old, 8.3% among teenagers 15-18 years old) and have tend to increase among teenagers in the dynamics of 5 years. One of the most likely important reasons for the deterioration of children's health is a violation of the nutritional structure and a decrease in its quality. So, (3.6 ± 0.8) % of primary schoolchildren eat only twice a day. Most children eat fish only once a week and 4.5% of schoolchildren have not eaten fish in the last 30 days. Only 43.4% of schoolchildren consume milk and dairy products daily. Assessment of the actual state of school feeding showed the inconsistency in the work of the medical service and teachers in the basic issues of its organization, quality control, distribution of duties and responsibilities.
Conclusions. There are high incidence rates for certain classes of diseases аmong school-age children, in particular the digestive system. A negative sign of schoolchildren’s eating behavior is the deficiency of basic nutrients in their daily diet in accordance with physiological needs. The modern state of catering in educational institutions necessitates the implementation of system monitoring of its quality, usefulness, safety, and the physiological needs of direct consumers.
STATE OF THE PLATELET HEMOSTASIS IN THE MIDDLE-AGED AND THE ELDERLY HYPERTENSIVE PATIENTS
Authors: Pasko V. S. 
Published: June 2020

It has long been known that complications of essential hypertension are associated mostly with disorders of blood coagulation system and degree of absolute risk of cardiovascular events is growing with increasing of age. That is why much attention is paid to more detailed study of mechanisms of thrombosis as the component of complications of essential hypertension through lens of hemostatic changes at present. Therefore, regulatory mechanisms of initiation of thrombus formation and participation of platelet hemostasis are studied in hypertensive patients insufficiently today.
The aim of the study was to identify the baseline levels of the platelet hemostasis indices in the middle-aged and the elderly hypertensive patients.
Material and methods. We performed the comparative assessment of status of the platelet hemostasis in 63 middle-aged (group I) and 53 elderly patients (group II) respectively to clarify this issue in our work. Patients of the surveyed groups were comparable in age, sex and related pathology. The control group consisted of 15 patients for every of the surveyed groups (group III the middle-aged and group IV the elderly respectively) matched with basic by age and gender.
Conclusions. Therefore, there is the increase in platelet activity depending on age in the middle-aged and the elderly hypertensive patients that is manifested by adrenaline stimulation most clearly. In addition, the most significant changes are determined in the spontaneous and the adrenaline-induced aggregation namely in amplitude and slope of aggregation in the spontaneous and time of maximal aggregation in the adrenaline-induced aggregation in the patients of older age group compared with the middle-aged patients. The substantial deceleration of time of maximal aggregation during the adrenaline stimulated aggregation in 1,6 times (p<0,001) in the elderly patients confirms the expressed thrombogenicity and sensitiveness to neurohumoral influences too. Thus, the blood plasma thrombogenicity revealed in the study of the platelet hemostasis in the elderly indicates a high probability of thrombotic complications developing in this category of the patients and this is consistent with literature.
CURRÍCULO E AVALIAÇÃO: CONCEPÇÕES, RELAÇÕES E REFLEXÕES
Authors: Ferreira Sergina Maria Xavier Falcão , Santos Vilma de Albuquerque , Rêgo Ana Maria da Cunha , Vieira Manuelle Patrícia Ramos 
Published: June 2020

O presente artigo tem como objetivo ampliar a discussão acerca da relação entre currículo e avaliação. Desde o processo da formação do currículo planejado e desenvolvido, como também refletir seu espaço no embiente escolar. Tendo em vista, que sua concepção se reflete nas práticas pedagógicas, influenciando o processo avaliativo. Para isso, foi realizada uma pesquisa bibliográfica que tratou acerca da origem do conceito, dos desafios atuais e dos desafios da prática docente. Conclui-se que se faz necessário construir um currículo significativo, aberto ao novo e sempre pronto para ser reavaliado, como uma forma de pensar o mundo, um currículo vivo, onde as questões cotidianas apresentam-se como material de estudo e análise para toda a comunidade escolar, e é nesse contexto de um currículo vivo e significativo que será possível formar cidadãos que atuem e se posicionem no mundo em quevivem.
PENGARUH PEMBERIAN BOKASHI PUPUK KANDANG TERHADAP PERTUMBUHAN DAN PRODUKSI BEBERAPA VARIETAS TANAMAN JAGUNG (Zea mays L)
Authors: Susi Salhan, SP, MP ,dan Zinatal hayati, SP Fivi Yedmi 
Published: June 2020

Penelitian tentang pengaruh pemberian Bokashi pupuk kandang terhadap pertumbuhan dan produksi beberapa varietas tanaman jagung (Zea Mays L), penelitian ini dilaksanakanan pada bulan februari sampai mei 2012, yang bertempat di sungai Salak Kecamatan Tempuling Kabupaten Indragiri Hilir.
Penelitian ini menggunakan rancangan acak kelompok (RAK) yang disusun secara faktorial yang terdiri dari 2 faktor dan 3 ulangan. Faktor B adalah Bokashi pupuk kandang yang terdiri dari 4 taraf yaitu BO (tanpa pemberian bokashi pupuk kandang) B1 (5 ton/ha) dan B2 (10 ton/ha), serta B3 (15 ton/ha) sedanglan faktor v adalah varietas yang terdiri dari 3 taraf yaitu V1 (pioneer), V2 (N 35), dan V3 (NT 10).
Parameter yang diamati adalah tinggi tanaman, panjang daun ke tujuh, berat brangkasan basah, berat brangkasan kering, berat tongkol pertanaman sampel, diameter tongkol, produksi per plot, dan berat 100 biji. Selanjutnya data yang diperoleh diolah secara statistik, apabila F hitung lebih besar dari F tabel dilanjutkan dengan uji lanjut tukey HSD pada taraf 5%.
Hasil penelitian meenunjukan bahwa interaksi bokashi pupu kandang dan varietas berpengaruh nyata terhadap berat tongkol dan produksi per plot, akan tetapi tidak berpengaruh nyata terhadap terhadap tinggi tanaman, panjang daun ke tujuh, 1000 biji. Untuk perlakuan bokashi pupuk kandang secara tunggal berpengaruh nayata terhadap diameter tongkol, akan tetapi tidak berpengaruh nyata terhadap tinggi tanaman, panjang daun ketujuh, berat brangkasan basah, berat brangkasan kering, berat tongkol, produksi per plot serta berat 1000 biji., akan tetapi tidak berbeda nyata dengan tinggi tanaman, panjang daun ke tujuh, berat brangkasan kering, dan diameter tongkol. Varietas terbaik adalah NT10
Kata kunci: Bokashi Pupuk Kandang Varietas, Pertumbuhan dan Produksi Jagung.
Myocardial ischemia in neonate with perinatal asphyxia: Electrocardiographic, echocardiographic and enzymatic correlation
Authors: Merchant Saira , Meshram Rajkumar M , Khairnar Devendra 
Published: June 2020

Objective: The objective of this study is to evaluate the presence and severity of cardiac involvement in asphyxiated neonates and to established which clinical and laboratory parameters (electrocardiogram [ECG], echocardiography [ECHO], and cardiac enzyme) are reliable predictors of myocardial ischemia. Design: Nested case–control study. Setting: Neonatology unit of tertiary care institute. Materials and Methods: The study group consist of 90 term neonates who had APGAR score <7 at 5 min as cases and 90 term neonate who had APGAR score >9 at 5 min as controls. On the 2nd day of life (between 24 and 36 h), all neonate underwentECG, ECHO, and enzyme estimation (CK-MB). Result: The cases were divided into three groups according to SARNAT scale andGroup I consist 25, Group II - 54, and Group - III, 11 neonates. The mean gestational age was 36.97±0.35 and 37.12±0.46 week for cases and controls respectively while mean birth weight was 2.79±0.36 kg and 2.68±0.76 kg for cases and controls, respectively. ECG changes were present in 70 (77.7%) of cases. ECG changes of Grade 3 and 4 were present in only Group III neonates and all neonates with Grade 4 changes were died in 1st week of life. Fractional shortening (FS) decreased progressively from Group I to Group III (p<0.001) and showed a significant difference between cases and controls as well as in different groups except in controls versus Group I. Peak aortic velocity behaved similarly. Concerning mean acceleration, the significant difference wasobserved between control and cases (all 3 groups). CK-MB activity increased from Group I to Group III and statistically significant difference was seen in controls and different Groups as well as in between different groups except in Controls versus Group I. Conclusion: Severe ECG changes (Grades 3 and 4), CK-MB elevation and reduced FS can be considered as reliable marker of myocardial ischemia in perinatal asphyxia.
Umbilical coiling index as a marker of perinatal outcome: An analytical study at Navodaya Medical College, Raichur
Authors: Kumar Sandeep , Chetty Sanjeev 
Published: June 2020

Objectives: To measure the umbilical coiling index (UCI) postnatally and to study its association with adverse antenatal and perinatal outcome. Materials and Methods: This prospective study was carried out in the department of pediatrics at Navodaya Medical College, Raichur, Karnataka, from June to July 2016. 200 patients who were in active labor irrespective of their parities, who had singleton pregnancies with live babies who were either delivered by vaginal, instrumental, or lower segmental cesarean section were included in the study and multiple pregnancies, malpresentations, previously diagnosed intrauterine device, and elective cesarean section were excluded. UCI was calculated at the time of delivery by dividing the total number of coils by the total umbilical cord length in centimeters. Its association with various maternal and perinatal risk factors was noted. The statistical tests were the Chi-square test and assessed with EPI Info Version 12.0 software and statistically analyzed. Results: The mean UCI was 0.25±0.03. Hypocoiling or UCI <10th percentile (<0.11) was found to be significantly associated with low APGAR at 1 min and 5 min, meconium stained liquor (MSL), abruption, abnormal fetal heart rate (FHR), neonatal intensive care unit (NICU) admission, low birth weight, and intrauterine growth restriction. Hypercoiling or UCI >90th percentile (>0.37) was found to be associated withpregnancy-induced hypertension, preterm, diabetes mellitus, postpartum hemorrhage, polyhydramnios, NICU admission, abnormal FHR, MSL, and low APGAR at 1 min. Conclusion: Abnormal UCI is associated with several antenatal and perinatal adverse features.
Parental knowledge on the optional vaccines and the barriers in their use: A rural hospital-based study
Authors: Ambike Deepali , Tambade Viraj , Poker Faisal , Ahmed Kaenat 
Published: June 2020

Background: Knowledge, attitude, and practices regarding the vaccines administered under the National Immunization Programme have been studied in different settings; however, studies regarding optional or newer vaccines in India are scarce. Objectives: To assess the parental knowledge about routine vaccination with special focus on newer vaccines and to identify the reasons for delay/non-administration of newer vaccines. Materials and Methods: This study is a cross-sectional study conducted in pediatric immunization clinic of MIMER Medical College, Talegaon (D) from May to September 2016. About 300 parents wereinterviewed with a semi open questionnaire. Results: Over all awareness and knowledge about the newer vaccines was very poor, i.e., only 32.5% of the total respondents. The majority (57.8%) of respondents was totally unaware about the optional vaccines and reasons for not administering the vaccines, despite being aware, were cost factor and travel constraints to the hospital which was present in 5% of the total respondents. Conclusion: Lack of knowledge among parents/caregivers about the optional vaccines and those who had knowledge regarding the vaccines, cost and distance to centers where they are available were the major constraints in immunization.
Spinal cord atrophy and myelomalacia following triple intrathecal chemotherapy in a patient of relapsed acute lymphoblastic leukemia
Authors: Agrawal Sheesham , Sulaniya Pawan Kumar , Garg Kapil , Sitaraman S , Sulaniya Chandrakanta 
Published: June 2020

Paraplegia in a case of leukemia is an uncommon finding. It can be disease related, therapy related, or both. It may or may not be reversible or curable. Here, we are discussing an unusual acute life-threatening, therapy related condition, where triple intrathecal therapy in a relapsed acute lymphoblastic leukemia child led to severe spinal cord atrophy and myelomalacia causing acute paraplegia with urinary retention. Subsequently, the patient developed respiratory failure and succumbed to death. There is very few case reported of this complication. The aim of this case report is to sensitize, the pediatricians and pediatric oncologists about this life-threatening complication of chemotherapy.
Neonatal tooth with bilateral cleft lip and palate: A case report with review of literature
Authors: Kamble Amol , Dash Jayant Kumar , Sahoo Prasanna Kumar , Jadhav Ganesh , Velani Priyam 
Published: June 2020

Natal and neonatal teeth are present in the oral cavity at birth and during the first 30 days of life, respectively. Management of such teeth is a treatment challenge. The incidence of such natal and neonatal teeth is reported to be 1 in every 1125-30,000 births, respectively. Cleft lip and palate (CLP) is a common dentofacial congenital anomaly of the oral cavity and may be present unilaterally or bilaterally. The occurrence of association of such teeth with unilateral and bilateral CLP cases is reported to be 2% and 10%, respectively. The presence of natal/neonatal teeth in the cleft area complicates the child’s health only in few cases. There is a paucity of information in the literature regarding the simultaneous occurrence of neonatal teeth in bilateral CLP cases. The present paper reported the management of a neonatal tooth present in association with complete bilateral CLP in a 12-day-old male child with review of literature.
Rodenticide poisoning in children: A study of clinical profile and electrocardiographic changes
Authors: Sugunan Sheeja , Krishnan Rekha , Kumar K K Santhosh , Geetha S 
Published: June 2020

Objectives: To study the clinical profile and electrocardiographic (ECG) changes in rodenticide poisoning in children. Methods: Patients admitted with a history of ingestion of rat poison between October 2014 and October 2016 were included in the study. Clinical history was taken in detail, and stomach wash samples were sent for toxicological analysis. Continuous ECG monitoring was done in all cases. Investigations to assess organ functions and coagulation profile were done at admission and repeated as indicated. Results: There were 17 cases of rodenticide poisoning. Zinc phosphide was the rodenticide identified in 50% of cases, bromodiolone in 30%, and yellow phosphorous in 20% cases. Only 23% presented within 1 h of ingestion and only 12% received stomach wash from referring hospital. Out of the 17 cases, 12 cases (70%) were symptomatic, of which 42% hadminor symptoms such as vomiting and abdominal pain and 58% had major symptoms including dysrhythmias, shock, coagulation abnormality, hepatic failure, and seizures. ECG changes were observed in 7 cases (42%), and coagulopathy was seen in 2 (12%) cases of which one had hepatic failure. The mean time of onset of ECG changes was 19.7 h (range 9-36 h). The overall mortality rate was 17.6%. Cardiac arrhythmia was the most common cause of death (66%). Conclusion: Zinc phosphide has been detected as the most common chemical being used as domestic rodenticide. Transient rate abnormalities, metabolic acidosis, fever, and leukocytosis are early markers of toxicity and they should be looked for in all cases. General public, medical, and aramedicalpersonnel should be made aware of the toxic nature of rodenticides.
Maanasa: An early individualized remedial educational intervention model for scholastic backwardness among upper primary students
Authors: Jayaprakash R , Rajamohanan K 
Published: June 2020

Background: Scholastic backwardness is called as the learning achievement which is below the expected for a given age, cognitive skills, and schooling. Early identification and remedial measures are to be initiated at school level to control its lifelong impact. Objective: The objective of this study is to evolve an early individualized, remedial educational intervention model for the scholastic backwardness among upper primary students at the school level by the resource teachers. Materials and Methods: Whole upper primary students of the four government schools of the South Maararikkulam Grama Panchayath constituted the study population. The scholastic backwardness among them was identified and referred to specially trained resource teachers who were appointed in the schools under Maanasa project. They were graded as mild, moderate and severe category based on the level of scholastic backwardness. Children were given 1 academic year of individualized educational intervention along with inclusive education. Apart from these interventions, families of the identified students were given psychosocial interventions to create a learningfriendly atmosphere in their families. Learning skills of the scholastically backward students were re-assessed at the end of academicyear. Results: Out of total 629 students, 147 had scholastic backwardness (23.7%). Among these, 68 had mild, 60 moderate, and 19 had severe scholastic backwardness on reading skill grading. Psychosocial problems including alcoholism, domestic violence, quarrelsome events, and abandoned family were noticed among 48.7% of the parents of scholastically backward students. Reassessment at the end of academic year showed improvement of scholastic skill among 52.38% of the students. Conclusion: The present study proves that scholastic backwardness can be successfully approached and intervened at school level itself by impartingindividualized educational interventions by trained resource teachers. The parents should be taken into confidence for successful intervention.
Evidence-based focused approach for fulfillment of aims: Experiences of an asthma clinic
Authors: Jain Col Sunil , Thapar Col Rajeev Kumar , Mallick Maj Abhishek , Tiwari Sudhanshu , Yogesh Dakhane , Abhijith Y V 
Published: June 2020

Background: A new health system for the 21st century should be based on the best scientific knowledge, according to the Institute of Medicine, US. Objective: We have evaluated the effectiveness of asthma clinic providing comprehensive care based on the best available scientific evidence. Materials and Methods: This intervention study was conducted in a tertiary care hospital having a devoted asthma clinic for the comprehensive management. All children diagnosed as having asthma were included, and data of cases managed from July 2014 to June 2016 were analyzed. Intervention - comprehensive management of asthma including assessment, monitoring, health education, avoidance of triggers, management of comorbid conditions, appropriate medications, written asthma action plan, and counseling for follow-up. Outcome measures were treatment direction, asthma control, emergency visits, and hospitalizations. Results: 260 children were treated over a 2-year period. The effects of focused approach with progressive expertise lead to statistically significant benefits over the two successive years from July 2014 to June 2015 and July 2015 to June2016. These were in: (i) Treatment direction: Cases requiring stepping up of treatment decreased from 36.49% to 17.24% (relative risk [RR]: 0.473 [95% confidence interval {CI}: 0.249-0.895]); p=0.01229, (ii) asthma control: Cases with not well-controlled asthma decreased from 16.44% to 7.02% (RR 0.427: [95% CI: 0.199-0.914]); p=0.045, (iii) emergency department visits decreased from 35.62% to 21.05% (RR 0.591: [95% CI: 0.39-0.897]), p=0.00766, (iv) hospitalizations decreased from 16.44% to 5.26% (RR 0.32: [95% CI: 0.135-0.757]), p=0.00462. Conclusion: Establishing an asthma clinic and progressive expertise leads to significant beneficial results.