bluuebunny/crossref_metadata_2025_split huggingface dataset:
Canonical analytical solutions of wave-induced thermoelastic attenuation
Authors: Carcione José M , Gei Davide , Santos Juan E , Fu Li-Yun , Ba Jing 
Published: January 2020

SUMMARY
Thermoelastic attenuation is similar to wave-induced fluid-flow attenuation (mesoscopic loss) due to conversion of the fast P wave to the slow (Biot) P mode. In the thermoelastic case, the P- and S-wave energies are lost because of thermal diffusion. The thermal mode is diffusive at low frequencies and wave-like at high frequencies, in the same manner as the Biot slow mode. Therefore, at low frequencies, that is, neglecting the inertial terms, a mathematical analogy can be established between the diffusion equations in poroelasticity and thermoelasticity. We study thermoelastic dissipation for spherical and cylindrical cavities (or pores) in 2-D and 3-D, respectively, and a finely layered system, where, in the latter case, only the Grüneisen ratio is allowed to vary. The results show typical quality-factor relaxation curves similar to Zener peaks. There is no dissipation when the radius of the pores tends to zero and the layers have the same properties. Although idealized, these canonical solutions are useful to study the physics of thermoelasticity and test numerical algorithm codes that simulate thermoelastic dissipation.
On strong stability of explicit Runge–Kutta methods for nonlinear semibounded operators
Authors: Ranocha Hendrik 
Published: January 2020

AbstractExplicit Runge–Kutta methods are classical and widespread techniques in the numerical solution of ordinary differential equations (ODEs). Considering partial differential equations, spatial semidiscretizations can be used to obtain systems of ODEs that are solved subsequently, resulting in fully discrete schemes. However, certain stability investigations of high-order methods for hyperbolic conservation laws are often conducted only for the semidiscrete versions. Here, strong stability (also known as monotonicity) of explicit Runge–Kutta methods for ODEs with nonlinear and semibounded (also known as dissipative) operators is investigated. Contrary to the linear case it is proven that many strong-stability-preserving (SSP) schemes of order 2 or greater are not strongly stable for general smooth and semibounded nonlinear operators. Additionally, it is shown that there are first-order-accurate explicit SSP Runge–Kutta methods that are strongly stable (monotone) for semibounded (dissipative) and Lipschitz continuous operators.
Syrian Refugees in Canada and Transculturalism: Relationship between Media, Integration and Identity
Authors: Mohamed Eid , Bastug Mehmet 
Published: January 2020

AbstractThe process of integration of Syrian newcomers into Canada is multifaceted. The Canadian government, in its efforts to welcome refugees, has provided services that smooth this process over on many fronts. While financial and support services are essential to feelings of comfort, safety and security, feelings of identity and belonging constitute a never-ending process. In a globalized world, country of residence can easily change, but attachment to issues in the country of origin enlists a much more complex relationship. This article seeks to explore Syrian newcomers’ pre-migration and post-migration experiences and the influence of such experiences on their sense of belonging and identification. This article also seeks to understand their media-consumption habits. In doing so, the level of involvement of Syrian refugees in issues of host society versus issues in Syria or the Arab world becomes apparent. Through highlighting their level of involvement, this research hopes to uncover the feelings of responsibility to democratic change and the revolutionary process in Syria.
Effect of Blood Pressure Variability During the Acute Period of Subarachnoid Hemorrhage on Functional Outcomes
Authors: Ascanio Luis C , Enriquez-Marulanda Alejandro , Maragkos Georgios A , Salem Mohamed M , Alturki Abdulrahman Y , Ravindran Krishnan , Fehnel Corey R , Hanafy Khalid , Ogilvy Christopher S , Thomas Ajith J , Moore Justin M 
Published: January 2020

Abstract

BACKGROUND
The association of blood pressure variation with poor outcomes in aneurysmal subarachnoid hemorrhage (aSAH) is unknown.

OBJECTIVE
To evaluate the association of systolic blood pressure (SBP) variation and clinical outcomes in aSAH.

METHODS
We conducted a retrospective chart review of all aSAH patients treated at an academic institution between 2007 and 2016. Patient demographics, aSAH characteristics, and blood pressure observations for the first 24 h of admission in 4-h intervals were obtained. SBP variability metrics assessed were mean, standard deviation, maximum, minimum, peak, trough, coefficient of variation, and successive variation. The primary outcome was a composite of the modified Rankin scale as good (0-2) or poor (3-6) at last follow-up. Comparisons between outcome groups were performed. Logistic regression models for each significant SBP metric controlling for potential confounders were constructed.

RESULTS
The study population was 202 patients. The mean age was 57 yr; 66% were female. The median follow-up time was 18 mo; 57 (29%) patients had a poor outcome. Patients with poor outcomes had higher standard deviation (17.1 vs 14.7 mmHg, P = .01), peak (23.5 vs 20.0 mmHg, P = .02), trough (22.6 vs 19.2 mmHg, P < .01), coefficient of variation (13.9 vs 11.8 mmHg, P < .01), and lower minimum SBP (101.4 vs 108.4, P < .01). The logistic regression showed that every 1-mmHg increase in the minimum SBP increased the odds of good outcomes (odds ratio = 1.03; 95% CI = 1.001-1.064; P = .04). Models including other SBP metrics were not significant.

CONCLUSION
Hypotension was found to be independently associated with poor outcomes in patients with aSAH.
Association of a Remotely Offered Infectious Diseases eConsult Service With Improved Clinical Outcomes
Authors: Tande Aaron J , Berbari Elie F , Ramar Priya , Ponamgi Shiva P , Sharma Umesh , Philpot Lindsey , O’Horo John C 
Published: January 2020

Abstract
We performed a case–control study to evaluate an electronic, asynchronous infectious diseases consultative service at 2 rural hospitals within our health system. Patients with consultation via this platform (n = 100) had a significantly decreased odds of death at 30 days compared with propensity-matched controls (n = 300; adjusted odds ratio, 0.3; 95% confidence interval, 0.2–0.7; P = .003).
Cu∥-loaded polydopamine coatings with in situ nitric oxide generation function for improved hemocompatibility
Authors: Zhou Lei , Li Xin , Wang Kebing , Shen Fangyu , Zhang Lu , Li Peichuang , Shang Tengda , Wang Jin , Huang Nan 
Published: January 2020

AbstractNO is the earliest discovered gas signal molecule which is produced by normal healthy endothelial cells, and it has many functions, such as maintaining cardiovascular homeostasis, regulating vasodilation, inhibiting intimal hyperplasia and preventing atherosclerosis in the blood system. Insufficient NO release is often observed in the pathological environment, for instance atherosclerosis. It was discovered that NO could be released from the human endogenous NO donor by many compounds, and these methods can be used for the treatment of certain diseases in the blood system. In this work, a series of copper-loaded polydopamine (PDA) coatings were produced through self-polymerization time for 24, 48 and 72 h. The chemical composition and structure, coating thickness and hydrophilicity of the different copper-loaded PDA coatings surfaces were characterized by phenol hydroxyl quantitative, X-ray photoelectron spectroscopy, ellipsometry atomic force microscopy and water contact angles. The results indicate that the thickness and the surface phenolic hydroxyl density of the PDA coatings increased with the polymerization time.This copper-loaded coating has glutathione peroxidase-like activity, and it has the capability of catalyzing NO releasing from GSNO. The surface of the coating showed desirable hemocompatibility, the adhesion and activation of platelets were inhibited on the copper-loaded coatings. At the same time, the formation of the thrombosis was also suppressed. These copper-loaded PDA coatings could provide a promising platform for the development of blood contact materials.
H. G. Wells and the Fin-de-Siècle Gustatory Paradox
Authors: Valentine Colton 
Published: January 2020

Abstract
Beginning with a little-studied scene linking H. G. Wells’s ‘A Misunderstood Artist’ to Joris-Karl Huysmans’s À Rebours, this essay argues that a shared gustatory paradox runs from Huysmanian decadence, through the theories of Edwin Lankester and Max Nordau and into Wells’s writings. In each case, both a pragmatic and an aesthetic relationship to food can signify degeneration. The argument has three major stakes. The first is to reconstruct a robust intertextual relation between the oeuvres of Huysmans and Wells. The second is to complicate readings that cast two of Wells’s scientific romances, The Time Machine and The War of the Worlds, as mouthpieces for imperialist or (pseudo)scientific discourses (Anger, Brantlinger, Budd, Gailor, Gregory, Hendershot, Pick). The third is to build on recent studies of food representation in nineteenth-century literature and propose a novel interpretive method (Cozzi, Gyman, Lee). Taking up William Greenslade’s proposal that fictions construct a ‘network of resistances’ to discursive myths, I argue that gustatory scenes show Wells’s ‘network’ operating in a curious way. They neither kowtow to degeneration nor assume Greenslade’s active role of a ‘critical, combative humanist’. Instead, they give contradictory depictions of moralized eating that play out the myth’s structural paradox.
Functional characterization and expression patterns of PnATX genes under different abiotic stress treatments in Populus
Authors: Xu Zhiru , Huang Jiahuan , Qu Chunpu , Chang Ruhui , Chen Jinyuan , Wang Qi , Xi Qi , Song Yang , Sun Qi , Yang Chuanping , Liu Guanjun 
Published: January 2020

Abstract
The copper chaperone ATX1 has been investigated previously in the herbaceous plants Arabidopsis and rice. However, the molecular mechanisms of ATX1 underlying copper transport and functional characteristics in the woody plant Populus are poorly understood. In this study, PnATX1 and PnATX2 of Populus simonii × P. nigra were identified and characterized. Sequence analysis showed that PnATXs contained the metal-binding motif MXCXXC in the N-terminus and a lysine-rich region. Phylogenetic analysis of ATX protein sequences revealed that PnATXs were clustered in the same group as AtATX1. PnATX proteins were localized in the cytoplasm and nucleus. Tissue-specific expression analysis showed that PnATX1 and PnATX2 were expressed in all analyzed tissues and, in particular, expressed to a higher relative expression level in young leaves. Quantitative real-time PCR analysis indicated that each PnATX gene was differentially expressed in different tissues under treatments with copper, zinc, iron, jasmonate and salicylic acid (SA). The copper-response element GTAC, methyl jasmonate and salicylic acid responsiveness elements and other cis-acting elements were identified in the PnATX1 and PnATX2 promoters. Expression of β-glucuronidase driven by the PnATX1 promoter was observed in the apical meristem of 7-day-old Arabidopsis transgenic seedlings, and the signal strength was not influenced by deficient or excessive copper conditions. Both PnATX1 and PnATX2 functionally rescued the defective phenotypes of yeast atx1Δ and sod1Δ strains. Under copper excess and deficiency conditions, transgenic Arabidopsis atx1 mutants harboring 35S::PnATX constructs exhibited root length and fresh weight similar to those of the wild type and higher than those of Arabidopsis atx1 mutants. Superoxide dismutase activity decreased in transgenic lines compared with that of atx1 mutants, whereas peroxidase and catalase activities increased significantly under excess copper. The results provide a basis for elucidating the role of Populus PnATX genes in copper homeostasis.
The importance of conduction versus convection in heat pulse sap flow methods
Authors: Forster Michael A 
Published: January 2020

AbstractHeat pulse methods are a popular approach for estimating sap flow and transpiration. Yet, many methods are unable to resolve the entire heat velocity measurement range observable in plants. Specifically, the Heat Ratio (HRM) and Tmax heat pulse methods can only resolve slow and fast velocities, respectively. The Dual Method Approach (DMA) combines optimal data from HRM and Tmax to output the entire range of heat velocity. However, the transition between slow and fast methods in the DMA currently does not have a theoretical solution. A re-consideration of the conduction/convection equation demonstrated that the HRM equation is equivalent to the Péclet equation which is the ratio of conduction to convection. This study tested the hypothesis that the transition between slow and fast methods occurs when conduction/convection, or the Péclet number, equals one, and the DMA would be improved via the inclusion of this transition value. Sap flux density was estimated via the HRM, Tmax and DMA methods and compared with gravimetric sap flux density measured via a water pressure system on 113 stems from 15 woody angiosperm species. When the Péclet number ≤ 1, the HRM yielded accurate results and the Tmax was out of range. When the Péclet number &gt; 1, the HRM reached a maximum heat velocity at approximately 15 cm hr −1 and was no longer accurate, whereas the Tmax yielded accurate results. The DMA was able to output accurate data for the entire measurement range observed in this study. The linear regression analysis with gravimetric sap flux showed an r2 of 0.541 for HRM, 0.879 for Tmax and 0.940 for DMA. With the inclusion of the Péclet equation, the DMA resolved the entire heat velocity measurement range observed across 15 taxonomically diverse woody species. Consequently, the HRM and Tmax are redundant sap flow methods and have been superseded by the DMA.
Persistent Epithelial Defects and Corneal Opacity After Collagen Cross-Linking With Substitution of Dextran (T-500) With Dextran Sulfate in Compounded Topical Riboflavin
Authors: Höllhumer Roland , Watson Stephanie , Beckingsale Peter 
Published: January 2020

Purpose:
Collagen cross-linking (CXL) is a commonly performed procedure to prevent the progression of keratoconus. Riboflavin is an essential part of the procedure, which facilitates both the cross-linking process and protection of intraocular structures. Dextran can be added to riboflavin to create an isotonic solution. This case report highlights the importance of compounding riboflavin with the correct dextran solution.

Methods:
A retrospective case series.

Results:
Six eyes of 4 male patients with keratoconus aged from 20 to 38 years underwent CXL with substitution of 20% dextran (T-500) with 20% dextran sulfate in a compounded riboflavin 0.1% solution. Postoperatively, persistent corneal epithelial defects, stromal haze, and then scarring occurred. Corneal transplantation was performed for visual rehabilitation but was complicated by graft rejection followed by failure (n = 1 eye), dehiscence (n = 4), cataract (n = 2), post-laser ablation haze (n = 1), and steroid-induced glaucoma (n = 2). The visual outcome was <6/18 in all 6 cases because of irregular astigmatism and stromal haze. Thinning, vascularization, and scarring of the residual host tissue were noted.

Conclusions:
Substitution of dextran (T-500) with dextran sulfate in riboflavin solutions during CXL results in loss of vision from permanent corneal opacity. Residual host changes may compromise the results of corneal transplantation.
Management of Descemet Membrane Detachment After Forceps Birth Injury
Authors: Kancherla Swarupa , Shue Ann , Pathan Mohammad Faizan , Sylvester Christin L. , Nischal Ken K. 
Published: January 2020

Purpose:
To describe the clinical signs of Descemet membrane (DM) detachment due to forceps-related birth injury and its subsequent management using optical coherence tomography.

Methods:
Case report.

Results:
A 3-day-old term infant presented with left eye corneal clouding and a definitive history of traumatic forceps-assisted delivery. Despite topical therapy, corneal clouding persisted, necessitating an examination under anesthesia using ultrasound and handheld optical coherence tomography. This revealed not only a tear in DM but also a large detachment. Injection of air alone failed to achieve apposition of DM to the posterior stroma. Apposition was achieved only after penetration of the overlying cornea with the needle of a 10-0 nylon suture and release of clear viscous fluid. The cornea cleared within the first week and continued in the months to follow.

Conclusions:
Prolonged corneal edema should alert the physician to probable DM detachment after forceps-related birth injury. Injecting air alone may not be sufficient to reattach the detached DM.
Using relative brain size to better understand trophic interactions and phenotypic plasticity of invasive lionfish (Pterois volitans)
Authors: Becker McKenna 
Published: January 2020

AbstractPredator-prey dynamics provide critical insight into overall coral reef health. It has been shown that predator-prey relationships link the relative brain size of predators to their prey. Predation pressure forces prey to use decision-making skills that require higher cognition by inspecting and identifying predators and then adjusting their behavior to achieve the highest chance for survival. However, the predation pressure that prey face outweighs the pressure predators face to find prey, resulting in prey having larger relative brain sizes than their predators. There is little data on the relative brain size of fishes with few natural predators such asPterois volitans. This study compared the brain mass to body mass ratio ofPterois volitans, which have very few natural predators and thus very little predation pressure, to the brain mass to body mass ratio of their prey, possible predators, competitors, and taxonomically similar fish. Lionfish had a significantly smaller relative brain size than their predators, prey, and competitors, but was not significantly smaller than taxonomically similar fish. These results demonstrate that the morphological anti-predator adaptation of venomous spines causes little predation pressure. Thus, lionfish do not use the same cognitive skills as other prey or predators and, in turn, have smaller relative brain sizes.
CYTOTOXIC ACTIVITY OF A NEW ISOFORM L-AMINO ACID OXIDASE (BALT-LAAO-II) FROMBothrops alternatus(URUTU) SNAKE VENOM IN HUMAN LEUKEMIC HL60 CELLS
Authors: Heleno Maurício Aurelio Gomes , Nowill Alexandre , de Carvalho João Ernesto , Suni-Curasi Diego L. , Vilca-Quispe Julissa , Ponce-Fuentes Emilio Alberto , Obando-Pereda Gustavo Alberto , Ponce-Soto Luis Alberto 
Published: January 2020

AbstractIn this work we describe the isolation of a new isoform L-amino acid oxidase (LAAO) referred to as Balt-LAAO-II fromBothrops alternatussnake venom, which was highly purified using a combination of molecular exclusion (Sephadex G-75) and RP-HPLC chromatographics steps. When analyzed by SDS-PAGE, the purified Balt-LAAO-II presented a molecular weight of ∼66 kDa. The N-terminal amino acid sequence and internal peptide sequences showed close structural homology to other snake venom L-amino acid oxidases.This enzyme inducesin vitrocytotoxicity on cultured human leukemic HL60 cells. Cells were grown in RPMI medium and were incubated with isoform Balt-LAAO-II (1, 10 and 100 μg/mL) for up to 72 h. All three concentrations of venom markedly decreased the cell viability from 6 h onwards based on the staining with propidium iodide, the reduction of 3-(4,5-dimethylthazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and the uptake of neutral red.Flow cytometry showed that all isoform Balt-LAAO-II and whole venom concentrations induced apoptosis after 2-6 h of incubation. Morphological analysis of cells incubated with isoform Balt-LAAO-II and whole venom showed cell rounding and lysis that increased with the venom concentration and duration of incubation. These results show that isoform Balt-LAAO-II from venomBothrops alternatusis cytotoxic to cultured HL60 cells and suggest that this damage may involve apoptotic and oxidative stress pathways.
E. coliadhesion and biofilm formation on polydimethylsiloxane are independent of substrate stiffness
Authors: Arias Sandra L. , Devorkin Joshua , Civantos Ana , Allain Jean Paul 
Published: January 2020

AbstractBacterial adhesion and biofilm formation on the surface of biomedical devices is a detrimental process that compromises patient safety and material functionality. Several physicochemical factors are involved in biofilm growth, including the surface properties. Among those, material stiffness has recently been suggested to influence microbial adhesion and biofilm growth in a variety of polymers and hydrogels. However, no clear consensus exists about the role of material stiffness on biofilm initiation and whether very compliant substrates are deleterious to bacterial cell adhesion. Here, by systematically tuning substrate topography and stiffness while keeping the surface free energy of polydimethylsiloxane substrates constant, we show that topographical patterns at the micron and submicron scale impart unique properties to the surface that are independent of the material stiffness. The current work provides a better understanding of the role of material stiffness on bacterial physiology and may constitute a cost-effective and simple strategy to reduce bacterial attachment and biofilm growth even in very compliant and hydrophobic polymers.
Alfalfa leaf curl virus is efficiently acquired by its aphid vector Aphis craccivora but inefficiently transmitted
Authors: Ryckebusch Faustine , Peterschmitt Michel , Granier Martine , Sauvion Nicolas 
Published: January 2020

ABSTRACTAlfalfa leaf curl virus (ALCV) is the first geminivirus for which an aphid transmission was reported. Transmission by Aphis craccivora was determined previously to be highly specific and circulative. Using various complementary techniques, the transmission journey of ALCV was monitored from its uptake in an infected plant tissue up to the head of its vector. ALCV was shown to be restricted in the phloem using fluorescent in situ hybridization (FISH) and electropenetrography (EPG) monitoring of virus acquisition. Furthermore, the virus is heterogeneously distributed in the phloem as revealed by FISH and qPCR quantification of the viral DNA acquired by aphids monitored by EPG. In spite of the efficient ingestion of viral DNA, about 106 in a 15-hour feeding on ALCV infected plants, the individual transmission rate was at a maximum of 12%. Transmission success was related to a critical viral accumulation, around 1.6×107 viral DNA copies per insect, a threshold that needs generally more than 48 hours to be reached. Moreover, whereas the amount of acquired virus does not decrease over time in the whole aphid body, it decreased in hemolymph and heads. ALCV was not detected in progenies of viruliferous aphids and had no effect on aphid fitness. Compared to geminiviruses transmitted by whiteflies or leafhoppers or to luteovirus transmitted by aphids, the transmission efficiency of ALCV by A. craccivora is low. This result is discussed in relation to the aphid vector of this geminivirus and the agroecological features of alfalfa, a hardy perennial host plant.