bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ivermectin Inhibits Zika Virus Replication in Vitro But Does Not Prevent Zika Virus Infection in Rhesus Macaques (Macaca mulatta)
Authors: Cotrone Thomas S. , Kobylinski Kevin , Ponlawat Alongkot , Im-Erbsin Rawiwan , Sunyakumthorn Piyanate , Vanachayangkul Pattaraporn , Poolpanichupatam Yongyuth , Lohachanakul Jindarat , Klungthong Chonticha , Farmer Aaron , Fernandez Stefan , Hunsawong Taweewun 
Published: December 2024

Zika virus (ZIKV) outbreaks occur sporadically in tropical and subtropical regions. At present, there are no licensed vaccines or specific treatments available for ZIKV. Ivermectin is approved for use in humans as an antiparasitic drug. In this study, we conducted in vitro cell culture and in vivo experiments in rhesus macaque hosts and Aedes aegypti vectors to investigate the potential of ivermectin as an inhibitor of ZIKV infection. In LLC-MK2 mammalian cells, ivermectin inhibited ZIKV growth in vitro with 50% inhibitory concentration (IC50) values in the ranges of 7.4–21.3 µM and 4.0–11.6 µM for African and Asian genotypes, respectively. In C6/36 mosquito cells, ivermectin inhibited ZIKV growth in vitro with IC50 values in the ranges of 10.1–17.4 µM and 8.0–15.6 µM for the African and Asian genotypes, respectively. Despite these in vitro results, high-dose ivermectin prophylaxis (1.2 mg/kg for 3 consecutive days) failed to prevent ZIKV infection in rhesus macaque and did not alter ZIKV IgM antibody production. The secondary transfer of ivermectin from nonhuman primate blood to mosquito vectors at 3 days post-ZIKV inoculation and after the last dose of ivermectin administration showed no reduction in ZIKV replication in mosquitoes. However, mosquito survival rates were significantly (P <0.0001) lower after exposure to ivermectin, thereby potentially impacting ZIKV transmission through increased vector mortality. However, further investigation is needed to determine dosing regimens that may realize these effects in vivo.
Estudo da morte no contexto de cuidados paliativos: abordagens da medicina de família no ensino de comunicação de más notícias e finitude da vida
Authors: Morcerf Cely Carolyne Pontes , Rasmussen Emilly Barboza , Coutinho Guilherme Moreira de Queiroz , Marques João Mazzoncini de Azevedo 
Published: December 2024

A conversa sobre a morte é considerada no processo histórico de evolução humana alvo de sentimentos de negatividade e evitação, sendo um símbolo na prática médica de fracasso e impotência. Essa visão de estudos da morte como área negligenciada e atrelada à uma carga de peso e divergência do objetivo médico em salvar vidas, reduz os espaços de educação e capacitação nas escolas médicas frente à comunicação de más notícias e ao desenvolvimento de habilidades no contato com familiares e paciente sobre o processo de passagem da vida em seu ciclo tendo como a morte o ponto final de encerramento de uma história e merecendo ser tratada como um cuidado personalizado, humanizado e centrado na pessoa. Considerando a fragilidade das escolas médicas na abordagem da morte, o presente trabalho traz uma revisão narrativa e reflexiva sobre momentos de transição e impactos na formação do estudante de medicina que contribuem para a perpetuação da abordagem fragmentada, fria e evitativa, na desvalorização do ensino de humanidades e da melhoria de qualidade de vida em todas as fases do ciclo da vida, áreas que fazem interface entre a formação em medicina de família e cuidados paliativos.
Fertility Rate In Uzbekistan (1890-1990): Demographic Analysis of Gender Equality and Development (SDG 5)
Authors: Saidova Zebuniso , Buriev Amanulla 
Published: December 2024

Objective: This study aims to analyze the trends in birth rates in Uzbekistan from 1890 to 1990, identifying key factors influencing these trends and examining their demographic implications in relation to SDG 5: Gender Equality.

Theoretical Framework: Grounded in demographic transition theory, this research explores how birth rates fluctuate due to social, economic, and historical changes, with a particular focus on gender and age structure, and the impact of women’s education and employment on fertility rates, aligning with SDG 5.

Method: The study employs a historical analysis of birth rates in Uzbekistan over a century. It examines data from population censuses and assesses changes in demographic processes during periods of civil war, World War II, and the post-war years.

Findings: The results indicate that significant shifts in Uzbekistan's birth rates are closely tied to historical events, such as wars, government policies, and economic transitions. Improvements in women’s education and employment are shown to have influenced fertility rates, in line with the goals of SDG 5.

Research Implications: This study offers valuable insights for policymakers, contributing to demographic research and supporting strategies for gender equality in Uzbekistan.
Social, Cultural and Economic Analysis of Post-Pandemic Public Health (COVID-19) in the Case of Peru: an Evaluation of Approaches to Promote Health and Well-Being Within the Framework of the SDG
Authors: Mamani-Flores Adderly , Calatayud-Mendoza Alfredo Pelayo , Flores-Chambilla Salvador Gerardo , Vizcarra-Pinto Florentino , Morales-Quispe Erich Feliciano , Huaracha-Velasquez Jaime , Villanueva-Alvaro Naysha Sharon 
Published: December 2024

Objective: To examine the social, cultural, and economic consequences of the pandemic on public health in Peru, recognizing challenges and possibilities to strengthen the system, given that the pandemic aggravated existing inequalities, disproportionately impacting vulnerable groups, such as rural communities and individuals living in poverty, an evaluation of approaches to promote health and well-being within the framework of the SDG.

Theoretical framework: This research analyzes the way in which the pandemic has impacted several aspects of public health in the country, in a post-COVID-19 pandemic scenario that showed and aggravated the already existing weaknesses in the Peruvian health system, marked by its fragmentation and restrictions in infrastructure and human resources.

Method: A qualitative approach based on a documentary review and critical analysis was used for the development of the research.

Research implications: Lack of access to high-quality health services and unfavorable living conditions contributed to an increase in COVID-19 incidence and mortality in these groups. In cultural terms, distrust of the official health system and inclination towards traditional medicines impacted the community reaction to the virus. In economic terms, the pandemic severely impacted the middle class, decreasing its magnitude from 43.6% in 2019 to 24% in 2020, canceling out a decade of economic progress.

Results and discussion: The infodemic, or excess of information, including rumors and misinformation, made it difficult to implement effective public health strategies. In addition to job losses and reduced incomes, they restrict access to health services, intensifying pre-existing inequalities.

Originality/Value: To enhance public health in Peru after the pandemic, it is crucial to address social inequalities.
PENDEKATAN SYSTEMATIC LITERATURE REVIEW DALAM ANALISIS KETERSEDIAAN DAN KEBUTUHAN AIR IRIGASI
Authors: Ardana Putu Doddy Heka , Kembarajaya I Ketut , Pamungkas Tri Hayatining , Kariyana I Made , Wiradnyana I Gede Oka , Indramanik Ida Bagus Gede 
Published: December 2024

Pengaturan air irigasi tidak dapat dilakukan sembarangan, air irigasi harus diberikan sesuai dengan kebutuhan serta mempertimbangkan potensi air yang ada. Perlu dilakukan analisa ketersediaan dan kebutuhan air irigasi untuk mengetahui apakah kebutuhan air irigasi mampu tercukupi berdasarkan potensi air yang tersedia. Penelitian ini bertujuan untuk menggali informasi secara komprehensif sebagai bentuk identifikasi dan interpretasi dari penelitian terkait analisis ketersediaan dan kebutuhan air irigasi. Penelitian ini menggunakan metode Systematic Literature Review, yaitu dengan mengumpulkan, mengidentifikasi, dan menilai penelitian-penelitian terkait untuk memberikan interpretasi lengkap dari hasil penelitian. Hasil dari studi literatur didapatkan kesimpulan bahwa pemenuhan dan pengaturan air irigasi mencakup aspek ketersediaan dan kebutuhan air irigasi, dimana aspek tersebut dipengaruhi oleh sejumlah faktor dan parameter, diantaranya adalah debit sungai, curah hujan, evapotranspirasi, perkolasi dan pola tata tanam. Analisis ketersediaan dan kebutuhan irigasi dapat dilakukan dengan beberapa metode, tergantung pada lokasi penelitian dan data yang tersedia. Perhitungan neraca air penting dilakukan untuk merencanakan irigasi yang baik, terutama dalam pemberian dan pembagian air serta pemilihan pola tata tanam.
Occupational Therapy Interventions and Early Engagement for Patients in Intensive Care: A Systematic Review
Authors: Smith Morgan , Tsai Stephanie , Peterson Elyse 
Published: December 2024

Importance: Patients in intensive care units (ICUs) experience complex functional, physical, and cognitive needs that affect their engagement in activities of daily living (ADLs). Occupational therapy practitioners are uniquely positioned to address these needs to optimize patients’ functional recovery.
Objective: To examine occupational therapy–specific interventions as they relate to early engagement for patients in the ICU.
Data Sources: CINAHL, PubMed, ProQuest, OTseeker, and Cochrane Library databases.
Study Selection and Data Collection: The Cochrane methodology was used to collect, evaluate, and analyze articles, then reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guidelines for conducting a systematic review. Articles published from January 2012 to December 2021 evaluating adults who received occupational therapy interventions in ICUs with Level 1b, 2b, or 3b evidence were included.
Findings: Nine articles met the inclusion criteria and the research objective. Findings showed moderate evidence for ADLs, physical rehabilitation, and cognitive interventions in promoting functional outcomes for patients in the ICU.
Conclusions and Relevance: This systematic review introduces the term early engagement to describe occupational therapy–specific interventions for patients recovering in the ICU and supports occupational therapy’s role in this setting. Further research is needed to strengthen the evidence for occupational therapy–specific interventions and early engagement in the ICU.
Plain-Language Summary: Patients in the intensive care unit experience complex needs that affect their participation in activities of daily living (ADLs). Current research demonstrates moderate evidence for early engagement with ADLs, physical rehabilitation, and cognitive interventions performed by occupational therapy practitioners. This systematic review introduces the term early engagement, which captures how occupational therapy practitioners provide holistic interventions for patients in the intensive care unit to promote patient well-being and functional recovery.
Public Theology and Violent Rhetoric Examined in a Queer Womanist Critical Ethnography
Authors: Smallwood Teresa L. 
Published: December 2024

Public theology is an emerging constructive tool. In its inception, public theology was largely contextualized as the ‘public church.’ However, this thoughtful and empathetic book situates our publics everywhere. Smallwood contends that those who have been harmed by violent rhetoric from speech actors who would ‘other’ them retain the capacity to have and hold a theology. This different entry point allows for people of faith, those who are and those who are not associated with a particular communion of faith or denominational affiliation to claim public space for theologizing. Here, public theology is about the capacity of those who are ‘othered’ to affirmatively express their faith and to critically engage with those who would deny and denigrate their ontology.
‘Enduring hardship as a good soldier’ does not mean exposing oneself to verbal abuse week after week. Many LGBTQIA+ persons are assaulted, degraded, humiliated, and derogated from the pulpits and podiums of places of worship. This abuse caused many to turn away from their faith. Those who withstood protracted verbal abuse turned it inward and began to hate themselves. Through ethnography, Smallwood tackles these tough truths and engages with LGBTQIA+ persons. This book critically examines both the harm done to them and the help that is to come from a paradigmatic shift in care. Smallwood emphasises how spiritual self-assessment, ritual, and indigenous spiritual practices offer a way to wholeness and healing. Drawing from Yoruba epistemology, this work offers a framework for rebirth, renewal, and reclamation.
Sin and the Vulnerability of Embodied Life
Authors: Bray Charlotte 
Published: December 2024

This book explores how Catholics should speak about sin and grace in a world where structural injustice holds sway causing violence and harm.Bray brings diverse voices into creative dialogue to explore why unjust social situations can properly be called sin from a Catholic theological perspective, and how this sin can be understood to impact one’s agency, freedom, and historical condition vis-à-vis God.
Discussing disparate thinkers such as John Paul II, Judith Butler, Thomas Aquinas, and key Latin American liberation theologians, Bray deepens and constructively develops the Catholic understanding of social sin. She argues that the language of social sin presents us with an idea more theologically profound than just the identification of structural injustice; it depicts the power of collective human sinfulness to shape our lives and environments in ways which harm our relations with God, one another, and the rest of the created world.
Tunisia Under Ben Ali
Authors: Zisenwine Daniel 
Published: December 2024

Here, Daniel Zisenwine looks at Tunisia under the rule of Ben Ali, from 1987 when he rose to power until the 2011 protests that led to his downfall.
Sparked by the self-immolation of Mohamed Bouazizi in Sidi Bouzid in Tunisia, a wave of protests and uprisings spread across North Africa and the Middle East in late 2010 and 2011. The case of Tunisia has since been held up as an example of a ‘successful’ revolution, ousting its erstwhile ruler Zayn al-‘Abidin Ben Ali, leading to relatively free elections in October 2011. Zisenwine offers an analysis of this authoritarian regime from its early days, to the attempts in the 2000s to reform economically (but not, crucially, politically) and the societal discontent that eventually led to the 2011 protests. This book is vital for those researching the Middle East and North Africa, as well as for those interested in the anatomy of authoritarian regimes and their downfall.
New Turkey and the Far Right
Authors: Koru Selim 
Published: December 2024

Turkey is among a league of revisionist powers who are challenging the world order.Erdogan and his Islamist movement have aimed to create the “New Turkey”, preparing for a future that is less dependent on Western treaty allies and with an alliance structure of its own.
This book is about the political ideas driving Turkey’s regime change and foreign policy. It de-exceptionalizes Turkish politics, arguing that the “New Turkey” is part of a global trend of far-right nationalist movements like that of Donald Trump in the United States or Narendra Modi in India. In particular, the book reveals how far-right nationalist strands in Turkey have been nurtured by an existential resentment of the West, similar to those we are seeing in Russia. In tracing this resentment and its historical roots, the book invites policymakers and experts to better understand the new relationships Turkey is building with fellow revisionists including China and Russia, as well as Turkey’s involvement in the wars in Syria and Ukraine and Erdogan’s grand strategy for expansion.
The book is based on interviews with senior politicians and civil servants from across the country’s political spectrum. It also benefits from the author’s personal knowledge of Turkey’s far-right and Islamist traditions.
Russian Intelligentsia
Authors: Read Christopher 
Published: December 2024

The Russian Intelligentsiais the first single-volume history of a small but tremendously influential group of Russian intellectuals who achieved world renown in a variety of spheres. While previous accounts have addressed the history of individuals within this collective, Christopher Read offers the first explanation of the intelligentsia as a group. Read traces the vast debates that broke out between, and within, a multitude of intellectual factions, and contextualizes the ideas of the group within the framework of cultural, social, political, and economic development from the late 18th century to the present day.
This comprehensive yet accessible account demonstrates how the Russian intelligentsia morphed from one incarnation to the next, and effectively situates this change and continuity within a pan-European context. It considers the role of the intelligentsia throughout its origins, its transformation during the Russian Revolution, and since the collapse of communism, and highlights the beliefs of key figures such as Fyodor Dostoyevsky, Ivan Pavlov, Vladimir Lenin, Leon Trotsky, and Mikhail Gorbachev. In doing so, Read provides an essential guide to a fascinating aspect of Russia’s social and cultural history.
In Private
Authors: Turney Joanne 
Published: December 2024

The 1970s is often considered the period that design forgot.In Privatesets out to challenge this view, offering a cultural history of domestic interior design in Britain and America over the course of a decade that shaped the contemporary relationship between fashion and interiors.
With each chapter dedicated to a different room in the house, this book explores style, design and socio-cultural influence from the sitting room to the sauna, and from the kitchen to the conservatory. Considering the key critical discourses which arise from the style and function of each space,In Privatelooks at how the public sphere informed the decorating styles, furniture and furnishing of the private home, from shag pile carpets to Swedish duvets.
Demonstrating how the cultural environment of the 1970s sparked the ideas, styles and practices that have become common currency in today’s interior design, the book examines questions of sensuality, tactility, fashion, fantasy and gender. Illustrated throughout and packed with original research, it provides an insight into 1970s innovation and eclecticism in fashion, textiles and the domestic interior.
Post-work
Authors: Hester Helen , Stronge Will 
Published: December 2024

What does the future hold for work in our new age of crisis? How do we make sure that the uncertain future into which we are heading is heavenly and not hellish? How can we take the pleasures of work with us and eliminate the pains?
The answer: we need a post-work vision.
Questioning the received wisdom that work is good for you, that you are what you do and that 'any job is a good job',Post-workoffers a new challenge to the work-centred society. This timely book provides a vital introduction to the post-work debate - one of the most exciting political and theoretical currents of recent years. It explores not only what the future of workwillbe like, but more importantly what the future of workshouldbe like.
Pop & Postfeminism
Authors: Weidhase Nathalie 
Published: December 2024

Nathalie Weidhase conceptualises the female dandy as a figure that simultaneously embodies and disrupts postfeminist notions of femininity, including maintaining a physique conforming to contemporary beauty standards, constant self-surveillance and self-improvement, and the naturalisation of gender difference and heterosexuality.
She examines how music videos function as spaces in popular culture where the politics of the feminine can be articulated. These spaces allow female pop stars to be valued as artists with distinct contributions to popular music. Focusing on Amy Winehouse, Rihanna, Lady Gaga, and Lana Del Rey, Weidhase illuminates different characteristics of the postfeminist dandy in popular music. Amy Winehouse's work makes visible the commodification of the female spectacle in popular culture, highlighting how her image and persona were marketed and consumed. Rihanna performs black femininity as postfeminism’s abject Other. Lady Gaga queers monstrous motherhood and celebrates female musical lineage. Lana Del Rey's work demonstrates how whiteness operates as a canvas for postfeminist and post-racial fantasies, offering a platform for their deconstruction and critique.
In doing so, Weidhase provides a comprehensive understanding of how these pop stars navigate and challenge the intricate landscape of postfeminism, offering a nuanced perspective on contemporary femininity and its representations in popular culture.
Strabo
Authors: Lightfoot Jessica 
Published: December 2024

This book provides a short and accessible introduction to Strabo’s life, times and cultural context.It outlines the importance of geography and geographical writing in the Augustan period and its development in ancient Greece and Rome, as well as explaining Strabo’s significance and impact in antiquity and beyond. Jessica Lightfoot also explores how Strabo engages heavily with the works of Homer and other prominent Greek literary figures of the past. Our ancient geographer has much to tell us about myth, fiction and literature and their relation to geographical and historical prose. As a result, the reader is given an insight into the fundamentally philosophical origins of geography and the first development of that discipline in antiquity.
Strabo of Amasia is known to us today as the writer of theGeography, a seventeen-book monumental survey of the known world which dates to the early first century AD. As the earliest major ancient geographer whose work we possess, Strabo occupies an important place in the history of ancient culture, literature and science. His work is crucial in assessing the emergence of geography as a discipline. Its later reception had an important impact on conceptions of the world and the development of geographical and travel writing, especially in the 15th and 16th centuries.
This book provides a short and accessible introduction to Strabo’s life, times and cultural context. It outlines the importance of geography and geographical writing in the Augustan period and its development in ancient Greece and Rome and explains Strabo’s significance and impact in antiquity and beyond.
How Words Help Us Think
Authors: Salay Nancy 
Published: December 2024

A capacity to act for reasons is a key indicator of intelligence. A leaf floats this way and that as the wind currents shift, a drone moves up or down with the movements of its controller, but a cognitive agent decides to walk to the store to get some food. This deliberative capacity to think through hypothetical situations, to choose between the grocery store or the restaurant, requires representational intentionality, the ability to think about real and possible situations in the world. According to the mainstream zeitgeist in the cognitive sciences, this capacity exhaustively reduces to lower level processes and, as a consequence, cognitive research has been driven increasingly inwards and downwards to focus on activity at the neural and molecular levels.
Here, Nancy Salay argues that this move is deeply misguided. After revealing the central problems with this internalist idea, Salay puts forward an externalist paradigm of intentionality supported by recent empirical work in neuroscience, computer science, philosophy, animal cognition and developmental psychology. Drawing all of these insights together, she provides a unified framework in which to situate externalist views of intentionality, making progress towards a viable theory of cognition. This is a comprehensive theoretical guide and a valuable empirical resource for those who view cognition through an extended and enactive lens.