bluuebunny/crossref_metadata_2025_split huggingface dataset:
Photovoltaic organic interface for neuronal stimulation in the near-infrared
Authors: Airaghi Leccardi Marta Jole Ildelfonsa , Chenais Naïg Aurelia Ludmilla , Ferlauto Laura , Kawecki Maciej , Zollinger Elodie Geneviève , Ghezzi Diego 
Published: May 2020

AbstractOrganic materials, such as conjugated polymers, are attractive building blocks for bioelectronic interfaces. In particular, organic semiconductors show excellent performance in light-mediated excitation and silencing of neuronal cells and tissues. However, the main challenges of these organic photovoltaic interfaces compared to inorganic prostheses are the limited adhesion of conjugated polymers in aqueous environments and the exploitation of materials responsive in the visible spectrum. Here, we show a photovoltaic organic interface optimized for neuronal stimulation in the near-infrared spectrum. We adjusted the organic materials by chemical modification in order to improve the adhesion in an aqueous environment and to modulate the photoelectrical stimulation efficiency. As proof-of-principle, we tested this interface on explanted degenerated mice retinas, thus providing results on the efficiency and reliability of the device as an implant for neural stimulation.
Auftreten des Post-Finasterid-Syndroms nach Verschreibung von Propecia 1 mg-Tablette zur Behandlung der männlichen Glatzenbildung
Authors: Lehmann P. 
Published: May 2020

ZusammenfassungEin Patient wurde im Jahre 2013 mit Propecia 1 mg aufgrund einer androgenetischen Alopezie behandelt. Es traten bei ihm eine sexuelle Dysfunktion mit Erektionsschwäche und vermindertem sexuellen Verlangen auf, die auch nach Abbrechen der Therapie anhielt. Daraufhin machte der Patient gegenüber dem Facharzt einen Behandlungsfehler geltend aufgrund mangelhafter Aufklärung mit der Konsequenz einer fehlerhaften Behandlung. Der urologische Fachgutachter bejahte den Behandlungsfehler. Er war der Meinung, dass, auch wenn nur Einzelfälle mit geringer wissenschaftlicher Basis über das Post-Finasterid-Syndrom bekannt wären, der Facharzt über diese schwerwiegende Nebenwirkung den Patienten hätte aufklären müssen, dies insbesondere bei einer rein kosmetischen Indikation männlicher Glatzenbildung.Der dermatologische Gutachter schloss sich nicht dieser Meinung an. Im Verordnungsjahr 2013 existierten lediglich 2 Publikationen über Einzelfälle des Post-Finasterid-Syndroms. Diese Publikationen in peripheren Zeitschriften fanden noch kein allgemeines wissenschaftliches Echo und führten auch nicht zur Änderung der Fachinformation. Erst im Verlauf der Folgejahre wurde in der Postmarketing-Phase das Syndrom öfters beschrieben und fand auch Eingang in die Fachinformation. Da für die Beurteilung das im Jahre der Verordnung geltende wissenschaftliche Wissen entscheidend ist, kann dem Facharzt kein Behandlungsfehler vorgeworfen werden.
Pilotäre Zwischenergebnisse zur Evaluation eines
störungsspezifischen, körperpsychotherapeutisch orientierten
Gruppenbehandlungsprogramms für Menschen mit psychogenen
Anfällen
Authors: Senf-Beckenbach Philine , Hinkelmann Kim , Hoheisel Matthias , Devine Janine , Rose Matthias 
Published: May 2020

ZusammenfassungPsychogene nicht-epileptische Anfälle (PNES) treten im Kontext verschiedener
Erkrankungen auf. Die Ätiologie ist noch weitgehend unverstanden. Bisherige
Konzepte gehen von einer erhöhten Rate an Trauma – Folgestörungen als
ätiologische Erklärung für PNES aus, was sich durch Studien mehrfach belegen
ließ 1
2. Klinisch imponiert das Krankheitsbild
bedrohlich, wodurch die Betroffenen häufig intensivmedizinische Maßnahmen
erhalten, ohne dass sie davon profitieren 3.
v. a. in Epilepsiezentren häufen sich Betroffene, da hier eine diagnostische
Abgrenzung zu epileptischen Anfällen möglich ist. Oft gestaltet sich der
Übergang von der Diagnosestellung in der Epileptologie zur Weiterbehandlung in
die Psychosomatik schwierig, da sowohl Patienten/innen als auch Behandelnde oft
in somatischen Krankheitskonzepten verhaftet sind 28. Aufgrund der notwendigen Interdisziplinarität zwischen
Neurologie und Psychosomatik wurde an der Charité Universitätsmedizin Berlin
eine Spezialambulanz für Menschen mit dissoziativen Anfällen gegründet, welche
sich im Übergang von Neurologie zu Psychosomatik ansiedelt und als
Kooperationsprojekt funktioniert 27. Aus der
Ambulanz heraus wurde zudem ein Gruppenbehandlungsprogramm (Kördis) entwickelt.
Dieses modularisierte 10-wöchige Therapieprogramm wird im Folgenden inhaltlich
vorgestellt und ist weiterhin Gegenstand einer aktuell noch laufenden
randomisierten, kontrollierten Evaluationsstudie. In den hier vorgestellten
Pilotdaten aus der laufenden RCT Studie zeigte sich eine signifikante
Verbesserung der Anfallsstärke (gemessen mit der Liverpool Seizure Severity
Scale LSSS) sowie der Dissoziationsneigung (gemessen mit dem Fragebogen für
dissoziative Symptome FDS-20) durch das Therapieprogramm (LSSS-Wert
prä-interventionell: 49,2±4,2; LSSS-Wert post-interventionell: 46,8±5,4;
t(10)=2,73; p=0,02; FDS-20 -Wert prä-interventionell: 25,3±14,6; FDS-20 -Wert
post-interventionell: 19,7±8,8; t(10)=2,18; p=0,05).
Die Pandemiekatastrophe aus katastrophenrechtlicher und
-medizinischer Sicht
Authors: Walus Andreas , Holbe Fabian 
Published: May 2020

ZusammenfassungDie Corona-Pandemie löst auch in der Bundesrepublik Deutschland eine
Gefahrenlage aus, deren Auswirkungen – wie z. B. in Italien
– zu einem medizinischen Notstand führen können. Die
Überlastung des Gesundheitswesens oder anderer kritischer
Infrastrukturen können eine Pandemiekatastrophe auslösen. Das
deutsche Infektionsschutz- und Katastrophenschutzrecht sehen zahlreiche
Mechanismen der Katastrophenvorsorge und der Katastrophenabwehr vor. Dennoch
werden sowohl Behörden als auch Ärzte ethisch und rechtlich
schwierige Entscheidungen treffen müssen. Denn im Falle eines
Ressourcenmangels (z. B. von Impfstoffen oder
Beatmungskapazitäten) müssen konfliktträchtige
Auswahlentscheidungen getroffen werden. Einer Überprüfung
bedürfen die Regelungen zur Pandemievorsorge: Die Vorbereitung auf die
Pandemiebekämpfung muss eine klare und rechtsverbindliche Aufgabe aller
staatlichen und privaten Verantwortungsträger darstellen. Hierbei
spielen u. a. Planungen, Fortbildungen, Übungen und
Vorratshaltungen eine zentrale Rolle.
Bilateral FCR Tendon Injury Associated with Osteoarthritis of the STT Joint
Authors: Takami Hiroaki , Aso Kuniichi 
Published: May 2020

AbstractSubcutaneous flexor carpi radialis (FCR) tendon ruptures secondary to osteoarthritis of the scapho-trapezio-trapezoidal (STT) joint are very rare. A 53-year-old female suffered a subcutaneous FCR tendon rupture after noticing pain in her right wrist. Because of continuing pain and decreasing strength in her right hand, surgery of the STT joint arthrodesis and an FCR tendon reconstruction with free tendon graft was performed. Her left wrist gradually showed the same symptoms 9 years later. The STT fusion for her left wrist was then performed. The FCR tendon was partially worn out on the spur of the trapezial ridge as well. Only 10 cases of FCR tendon ruptures have been reported due to definite STT osteoarthritis in six English papers. We believe STT fusion should be done without hesitation before tendon rupture occurs, and when motion pain around the STT joint and decreasing grip strength exists. However, it is controversial whether the FCR tendon reconstruction should be done in addition to STT fusion.
Responsive Neurostimulation for Intractable Epilepsy in Phelan–McDermid Syndrome
Authors: Wolf Steven Marc , McGoldrick Patricia Engel , Garg Nikita , Ghatan Saadi , Panov Fedor , Moss Rachel , Singh Prashant , Geem Kevin Van 
Published: May 2020

AbstractResponsive neurostimulation (RNS) is an approved treatment for intractable epilepsy in the adult population but has not yet been approved for pediatric patients. We present here the first reported case of a 14-year-old adolescent with 22q13.3 syndrome (more commonly known as Phelan–McDermid syndrome) with intractable epilepsy who showed clinical improvement after implantation of an RNS device. The patient had trialed 10 antiepileptic drugs without improvement and despite magnetic resonance imaging (MRI) demonstrating left mesial temporal sclerosis (MTS), the patient was not considered as a candidate for temporal lobe resection due to multifocal seizure activity on electroencephalogram (EEG). At 23 months postoperatively, she has experienced 86.7% reduction in seizure frequency; a clinical improvement which emphasizes the importance of considering RNS treatment for those with intractable epilepsy in the pediatric population, even in the setting of known genetic syndromes.
Dissemination of international rankings: characteristics of the media coverage of the Shanghai Ranking in the French press
Authors: Barats Christine 
Published: May 2020

AbstractThe number of university rankings proliferated in the 2000s against a background of reforms in higher education (HE) and the development of a discourse on academic ‘excellence’. The analysis of the emergence and treatment in the French press of the so-called ‘Shanghai ranking’, the first international ranking to originate in the world of academia, makes it possible to objectify the characteristics of its dissemination in France from June 2003 when it was first published in China. Although there was no intention initially to have this ranking circulated in France, it ultimately became more widely known owing to its status as a useful resource for different actors working against a background of HE reforms in France. This article discusses the intensification of media coverage from 2007 onwards, as well as the role played by certain media organisations and players (analysis of French press corpus and interviews). It highlights the importance of depreciative framing for French universities to ‘create a buzz’ along with the co-construction of the process by different players. The ranking has become a journalistic resource, as well as a political argument for reforms and a communication tool for certain university presidents.
A transdisciplinary protocol evaluating auditory processing disorder (APD) in children using speech and non-speech stimuli and tools for common co-morbidities
Authors: Ahmmed Ansar Uddin 
Published: May 2020

Purpose
Effective combination of speech and non-speech tests, using pass–fail cut-off criteria consistent with that used to diagnose co-morbidities, in evaluating APD are explored.

Method
Retrospective- analysis of 80 children, 8 to 12 years-old, undergoing APD assessment. Filtered Words, Auditory Figure Ground 0 dB, Competing Words, Competing Sentences and Time Compressed Sentences from SCAN-3:C battery were used as speech tests and non-speech tests included Dichotic Digits, Gap Detection and Frequency Pattern. Comorbidities evaluated were language impairment, attention-deficit-hyperactivity disorder and impaired manual dexterity, using cut-off ≤ 10th centile in appropriate tools.

Results
Seventy-three participants (91.25%) were diagnosed with APD (≤ 9th centile in at least two tests) using speech plus non-speech tests. Speech tests alone diagnosed 60 (82%) and additional low linguistic load/non-speech tests helped in identifying the other 13 (18%). Sixty-six participants (82.5%) had APD plus co-morbidities, seven (8.75%) had APD only and the other seven (8.75%) had comorbidities without APD.

Conclusions
Initial evaluation by SCAN-3 battery followed by non-speech tests if necessary, will reduce test duration and improve child friendliness. Overlap between APD and comorbidities consistent with the literature is achieved if consistent pass/fail cut-off are used. The use of comorbidities to compare APD diagnostic criteria need to be explored.
Infrared spectroscopy analysis of montmorillonite thermal effects
Authors: Caccamo M T , Sabatino G , Bennardo A , Magazù S 
Published: May 2020

Abstract
The present work reports the analysis of the intramolecular OH stretching band obtained by Infrared spectroscopy measurements. In order to characterize the effect of montmorillonite on the properties of Lysozyme the so-called two-state model is adopted for the analysis of the intramolecular OH stretching band. This latter assumes that the OH stretching can be partitioned into two different states of intermolecular bonding. Such a result confirms that the montmorillonite leads to a stabilization of the Lysozyme structure. Moreover, the analysis of the spectra temperature dependence shows a montmorillonite-induced higher thermal restraint of the Lysozyme in respect to pure Lysozyme.
Oil spill removal using kenaf core fibers as biosorbent material
Authors: Siwayanan P , Ramachandran D G , Jamaluddin R , Ahmad S 
Published: May 2020

AbstractOffshore crude oil exploration has led to oil spillage in the sea and causes an enormous negative impact on the surrounding environment, animals and human beings. In this paper, studies have been carried out to utilize Malaysian grown Kenaf core fibers as biosorbent material to clean-up the spilled oil from the sea. Kenaf fibers have natural oleophilic characteristics and therefore would be suitable to be used as biosorbent material. Studies were conducted to understand the surface characteristics, to evaluate the absorption capacity under simulated sea conditions and to determine oil/seawater sorption characteristics of Malaysia grown Kenaf core fibers. The crude oil/seawater absorption capacity study has indicated that both 20 mesh and 40 mesh Kenaf fibers can absorb 4 times its original weight in crude oil upon short contact time with crude oil/seawater. This study also reveals that the Kenaf fibers tend to absorb seawater upon prolonged contact with crude oil/seawater. Based on the separate crude oil and seawater sorption tests, both 20 mesh and 40 mesh Kenaf core fibers were found to have the ability to absorb 5-6 times and 1-6 times of its original weight in crude oil and seawater respectively, depending on the contact time.
Electrochemical properties of ascorbic acid and folic acid under acidic solution
Authors: Abyor Handayani Noer , Anisa Krisanti Elsa , Sadeli Yunita , Kartohardjono Sutrasno , Mulia Kamarza 
Published: May 2020

Abstract
Ascorbic acid and folic acid are very important vitamins which have some crucial roles in human body’s metabolism, including enhancing iron absorption. Regardless of its roles, these vitamins are also known to be unstable and easily degraded in the processing by oxygen, pH, temperature, and UV light. Nowadays, microencapsulation may be a proper technique to overcome some of these shortcomings. However, there is a possibility of the changes in vitamin stability during encapsulation processes, particularly while using chitosan and acetic acid as wall material and solvent, respectively. In this study, cyclic voltammetry method was carried out for investigating the electrochemical properties of ascorbic acid and folic acid under acidic medium. The effect of scan rate (0.1; 0.2; 0.3 V/s) on the observed current was also studied. Furthermore, vitamin-aquadest solutions were also studied as a referred sample. Cyclic voltammetry was conducted using a three electrodes configuration connected to an electrochemical analyser. Platinum wire, graphite, and Ag/AgCl were employed as the working, auxiliary and reference electrodes, respectively. All the solutions were maintained for free oxygen by the degassing process. In general, the recorded currents of all solutions were increased while using a higher scan rate. Cyclic voltammogram also showed that ascorbic acid had two anodic peaks and two cathodic peaks which indicated that ascorbic acid undergoes reversible reaction. However, folic acid only had one anodic peak in water which represented an oxidation reaction. Furthermore, the electrochemical properties of ascorbic acid have a similar profile with folic acid while were in acidic solutions. Both vitamins have more positives anodic peak; hence depicted that acid could suspend the oxidation reaction.
Enhanced production of β-carotene suspensions using supercritical CO2 via naturally occurring Z-isomerization-accelerating catalyst
Authors: Zhang Yelin , Honda Masaki , Wahyudiono  , Kanda Hideki , Goto Motonobu 
Published: May 2020

Abstract

β-carotene has high antioxidant activity and its adequate intake can reduce the risk of various diseases. Thus, β-carotene can be utilized as a dietary supplement and valuable natural food colorant. Z-isomerization of β-carotene can reduce the crystallinity of (all-E)-β-carotene and improve the solubility of it in solvents. Preparing nanosuspensions of Z-isomer-rich β-carotene can improve the dispersibility of β-carotene in water and bioavailability of it. In previous work, Z-isomerization and encapsulation process of β-carotene was implemented in two separated steps. In this work, organic catalyst derived from plants was utilized for Z-isomerization of β-carotene. The Z-isomerization and emulsification-evaporation process were conducted simultaneously under supercritical CO2 assisted by ultrasound. β-carotene suspension produced in this work was characterized by UV-vis, HPLC and DLS. The nanosuspensions rich in Z-isomers of β-carotene has been successfully prepared using allyl isothiocyanate (AITC) as the catalyst for Z-isomerization. When the distributed processing was performed with 50mg, 100 mg AITC, the encapsulation efficiency and Z-isomerization ratio in the suspensions were approximately 6 times and 13 times higher than those of no catalyst. Adding AITC in the emulsification-evaporation process using SC-CO2 as a Z-isomerization-accelerating catalyst improved not only the Z-isomerization ratio of βcarotene but also the encapsulated β-carotene content in suspensions.
Utilization of Corn Cob Waste as an Alternative Composite Material of Motorcycle Non-asbestos Brake Lining
Authors: Sukirman  , Ma’mun S , Rusdi S , Fahruli A , Yulpando R E 
Published: May 2020

Abstract
One of the safety factors in riding a motorcycle is the braking system in which the brake lining plays an important role in the braking performance, therefore, application of an appropriate brake lining material which gives a low brake lining wear value is a must. The objective of this study is to evaluate the effect of brake lining material compositions on the value of brake lining wear. The brake lining was made from a mixture of corn cob powder, Al2O3, BaSO4, and polyester resin with a certain composition. The brake lining wear value was then determined by the Ogoshi wear testing by varying the material compositions. The brake lining wear values were then compared to those obtained from the brake linings existing in the market, e.g. Texiar. The results show that the higher the concentration of the corn cob, the better the value of the brake lining wear. This is due to the nature of the corn cob that gives less wear value compared to Al2O3. It was found that the brake lining wear value of 2.8 × 10−9 mm2/kg, corresponding to the brake lining wear value of Texiar, was achieved at which the compositions of the corn cob powder, Al2O3, BaSO4, and the polyester resin are 30, 30, 20, and 20 wt%, respectively. The result indicates that variations in the composition of constituent material have an influence on the brake lining wear value.
Preparation of Cationic Polyurethane Dispersion and Its Effectiveness as Denim Dye Fixing Agent
Authors: Sundang M. , Sipaut C. S. , Saalah S. 
Published: May 2020

Abstract
The issue encountered by the textile industry is that the colours are fading off, particularly in denim fabric, by constant washing, so fixing agent is needed to enhance the colour fastness of the denim fabric. Polyurethane is one of the promising types of nonformaldehyde dye fixing agents. It has good film covering properties and allows air permeability. In this study, cationic polyurethane dispersions (CPU) were syntheses and applied as fixing agent for sulphur dye denim fabric. Different formulation of CPU were synthesized using isophorone diisocyanate, different molecular weight of polyols, and tertiary amine. Formulated CPU were then analysed using FTIR, zeta potential analyser and viscometer. Zeta potential obtained was in the range of +8.1 mV to +41.7 mV indicates that some of the CPU particles tend to agglomerate and some are stable. After fixing treatment, colour fastness to crocking of the treated fabric has improved. Surface morphology changes were determined by SEM and it shows that smooth finishing fibre surface was obtained in treated black denim fabric.
New monopolar arrangement of electrodes to enhance the production of magnetite nanoparticles in an electrochemical cell
Authors: Setyawan H , Nurlilasari P , Widiyastuti W 
Published: May 2020

Abstract
Here, we proposed to increase the production rate of magnetite nanoparticles by electro-oxidation of iron in water using multi-electrode with an arrangement of conventional monopolar (CM) and alternating monopolar (AM). The production rate of the magnetite nanoparticles could be increased significantly using the proposed electrode arrangement compared to our previous method using one-pair of electrodes in the same system. The particle sizes ranged from 28 to 88 nm for the CM and from 20 to 25 nm for the AM arrangements. The performance of the AM arrangement was superior that of the CM arrangement in regard to production rate, particle size, and product purity. The production rates were approximately 20 and 30-fold increases for, respectively, the CM and AM arrangements compared to that of one-pair electrode. The magnetite particles produced using the CM arrangement contained impurities in the form of FeOOH and Fe2O3. On the contrary, only magnetite was identified in the particles prepared using the AM arrangement.
Synthesis of TiO2/GO nanocomposite for Methylene Blue Degradation
Authors: Kasmiarno L. D. , Floresyona D. , Raissa R. , Pambudi N. S. 
Published: May 2020

Abstract
In using visible light for commercially available photocatalytic TiO2 powder, the alteration of its chemical structure is required in which a metal or non metal ion is introduced to the naturally TiO2 compound in a process called doping. In this study, a graphene oxide is chosen as composite that can be functioned under visible light irradiation since it can extended light absorption range and can improved activity of TiO2/GO nanocomposite for enhancing charge separation. The TiO2/GO nanocomposite were characterized by SEM, TEM, XRD, and FT-IR. The TiO2/GO nanocomposites was active for reduction of Methylene Blue in aqueous media.
A hydrophobic cellulose aerogel from coir fibers waste for oil spill application
Authors: Fauziyah M , Widiyastuti W , Setyawan H 
Published: May 2020

Abstract
In this work, a hydrophobic cellulose aerogel was successfully developed from coir fibers waste. The hydrophobic aerogel was prepared using a simple sol-gel and freeze-drying method followed by surface modification using either trimethylchlorosilane (TMCS) or hexamethyldisilazane (HMDS). The operating temperature was varied around the boiling point of the modifying agent ranging from 50-70°C for TMCS and 110-130°C for HMDS. The concentration of modification agents was varied from 40-60 wt.% in n-Hexane. The best condition in term of its hydrophobicity was obtained at 50% of TMCS with a temperature of 60°C and 40% of HMDS at 120°C. The obtained aerogel has a good hydrophobic characteristic indicated by a high of water contact angle of 100-150°C. The aerogel also could selectively absorb only oil from the mixture of oil-water. Therefore, it could be the promising material used to overcome the oil spill issue due to its biodegradability, abundant availability, and low cost.