bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of the Antiviral Activity of Experimental Samples Obtained from the Grass and Roots of Alchemilla vulgaris L. Against Vaccinia Virus and Ectromelia Virus
Authors: Mazurkova N. A. , Protsenko M. A. , Filippova E. I. , Kukushkina T. A. , Vysochina G. I. , Lobanova I. E. , Mazurkov O. Yu. , Shishkina L. N. , Agafonov A. P. 
Published: November 2019

Introduction. The abolition of smallpox vaccination after its elimination in 1980 led to a decrease in the immunocompromised immunity in humans. Zoonotic monkeypox, camelpox, buffalopox and cowpox viruses that are close to the variola virus also pose a danger to humans. In Russia today there are no effective and safe medicines for the prevention and treatment of smallpox and other orthopoxvirus infections in humans and animals. The Lady's mantle (Alchemilla vulgaris) is a promising source for the development of new antiviral drugs. Previous studies have found that Alchemilla vulgaris shows activity against influenza virus and herpes simplex virus.Aim. The aim of this work was to study the chemical composition and antiviral activity of extracts from the roots and the grass of Alchemilla vulgaris against orthopoxviruses.Materials and methods. Qualitative analysis of the samples was performed by high performance liquid chromatography. Quantitative analysis was performed using a complex of spectrophotometric methods. To determine the toxicity and antiviral activity of experimental samples from Alchemilla vulgaris in vitro, a transplantable Vero cell culture was used. Antiviral activity of the obtained preparations was evaluated by reducing the infectivity (titer) of orthopoxviruses in the monolayer of Vero cells infected with orthopoxviruses in the presence of preparations with different concentrations relative to the cell culture infected with orthopoxviruses without the preparations.Results and discussion. It was shown that the experimental sample from Alchemilla vulgaris obtained by the method of ethyl acetate extraction from the roots of the studied plant and purified with chloroform contains mainly catechins and leucoanthocyanins (70 %). In parallel, extract from the raw mass of the grass of the plant purified with chloroform and ethanol contains the amount of flavonoids (71 %). Wherein the content of flavonoids in unpurified ethanol extracts from the roots and the grass of Alchemilla vulgaris composed 5 % and 6 %, respectively. It was revealed that purified preparations obtained from Alchemilla vulgaris roots when using ethyl acetate and ethanol as extractants showed antiviral activity against vaccinia virus and ectromelia virus, as well as preparations obtained from grass by ethanol extraction.Conclusion. Thus, purified ethyl acetate extracts from the roots and ethanol extracts from the wet grass mass of Alchemilla vulgaris exhibit antiviral activity against orthopoxviruses in vitro.
UJI AKTIVITAS ANTIBAKTERI SEDIAAN FACE WASH GEL LENDIR BEKICOT (Achatina fulica) DAN KOPI ROBUSTA (Coffea canephora) TERHADAP BAKTERI Staphylococcus aureus
Authors: Utami Novi Fajar , Nurmala Sara , Zaddana Cantika , Rahmah Rizqi Aulia 
Published: November 2019

Jerawat adalah masalah yang umum terjadi pada usia remaja dan dewasa karena adanya peradangan dan peningkatan produksi sebum pada kulit, diperparah dengan infeksi bakteri diantaranya Staphylococcus aureus. Penelitian ini bertujuan untuk menentukan formula terbaik sediaan face wash gel dari lendir bekicot dan kopi robusta berdasarkan uji hedonik dan menentukan aktivitas antibakteri sediaan face wash gel terhadap bakteri penyebab jerawat Staphylococcus aureus dengan kontrol positif sediaan facial wash komersial. Akivitas antibakteri ditentukan dengan menentukan Konsentrasi Hambat Minimum (KHM) menggunakan metode dilusi padat dan mengukur Lebar Daya Hambat (LDH) menggunakan metode difusi cakram.Dari hasil penelitian diperoleh nilai KHM dari ekstrak kopi berada pada konsentrasi 15%. Konsentrasi tersebut digunakan sebagai acuan pada pembuatan formula sediaan face wash gel dengan tiga perbedaan konsentrasi kopi F1 (5% ), F2 (10%), F3 (15%) dan satu konsentrasi lendir bekicot (12,5%). Berdasarkan hasil uji hedonik, formula 3 merupakan formula yang paling disukai panelis. Pada pengujian terhadap bakteri Staphylococcus aureus formula 3 menunjukkan aktivitas antibakteri tertinggi dengan LDH sebesar 9,160 mm dan memberikan hasil yang tidak berbeda nyata dengan kontrol positif.
ANALISIS KEBUTUHAN PENGATURAN BILLING RATE OLEH MENTERI KEUANGAN
Authors: Muliawan Yuliardi 
Published: November 2019

Saat ini pengaturan mengenai penyusunan RAB untuk jasa konsultansi telah tersedia baik yang dibuat oleh pemerintah maupun oleh asosiasi jasa profesi terkait. Namun demikian terdapat temuan BPK terhadap instansi pemerintah daerah dimana dalam penyusunan anggaran untuk satuan biaya billing rate mengacu pada SEB Kepala BAPPENAS dan Menteri Keuangan nomor 1203/D.II/03/2000 dan SE-38/A/2000 tanggal 17 Maret 2000 tentang Petunjuk penyusunan Rencana Anggaran Biaya (RAB) untuk jasa konsultansi (Biaya Langsung Personil (Remuneration) dan Biaya Langsung Non Personil (Direct Reimbursable Cost)). Menurut rekomendasi pada auditnya, BPK menyarankan agar Billing rate diatur oleh Menkeu melalui PMK Standar Biaya. Selanjutnya, melalui penelitian ini berusaha menjawab secara filosofis dan yuridis melalui telaah literature mengenai perlu atau tidaknya billing rate diatur oleh Menkeu melalui PMK Standar Biaya. Kemudian hasil dari penelitian ini diharapkan dapat menjadi bahan pertimbangan bagi pembuatan kebijakan terkait billing rate.
EFEKTIVITAS KEBIJAKAN STANDAR BIAYA PERJALANAN DINAS DALAM MENUNJANG KINERJA KEMENTERIAN NEGARA/LEMBAGA
Authors: Mahfudin Mahfudin 
Published: November 2019

This study aims to examine the effect of cost standard policy on official travel which is reflected in official travel expenditures on the achievement of Ministry/Institution program performance. The study was carried out in the 2016 where the budget for the cost of official travel was be reducted, with a quantitative analysis method, namely correlation analysis and CHAID methods. The results showed that official travel expenditure had a significant relationship and influence on the achievement of Ministry/Institution program performance in 2016, including the achievement of output of program.
Abstrak
Kajian ini bertujuan meneliti pengaruh kebijakan standar biaya perjalanan dinas yang dicerminkan dengan belanja perjalanan dinas terhadap pencapaian kinerja program Kementerian/Lembaga. Kajian dilakukan pada tahun anggaran 2016 dimana pada tahun tersebut telah dilakukan penghematan anggaran biaya perjalanan dinas, dengan metode analisis kuantitatif yaitu menggunakan analisis korelasi dan analisis CHAID. Hasil penelitian menunjukkan bahwa belanja perjalanan dinasmemiliki hubungan dan pengaruh yang signifikan terhadap pencapaian kinerja program K/L pada tahun 2016, termasuk pencapaian output program.
PENGARUH REKRUTMEN, FASILITAS OLAHRAGA, DAN PEMBERDAYAAN TERHADAP MOTIVASI SERTA DAMPAKNYA PADA PRESTASI ATLET DI PUSAT PEMBINAAN LATIHAN PELAJAR (PLPP) DAN PUSAT PEMBINAAN LATIHAN DAERAH (PPLD) ACEH
Authors: Rusdi Rusdi , Damrus Damrus 
Published: November 2019

This survey examines relationship between recruitment, sport facilities and empowerment through motivation toward athletes’ prestations. The survey took 119 athletes as data whose included in Pusat Pembinaan Latihan Pelajar (PLPP) dan Pusat Pembinaan Latihan Daerah (PPLD) Aceh. This research used path analysis to analyze the data and finds that recruitment, sport facilities and empowerment have an impact to the motivation and athletes’ prestations directly and indirectly. Through that condition indirectly all the exogenous factors have impact to athletes’ prestations. Key words : recruitment, sport facilities, empowerment, motivation, athletes’ prestations
Analisis Kendala Pengimplementasian Pendapatan pada SIMDA Keuangan di Pemerintah Provinsi Sulawesi Utara
Authors: Kewas Agnes MD , Karamoy Herman , Lambey Linda 
Published: November 2019

Abstract. SIMDA (Sistem Informasi Manajemen Keuangan Daerah) Keuangan is a compulsory requirement and a necessity for a provincial government to manage state’s money. The presence of SIMDA of Finance is expected to contribute to the process of state’s financial management, particularly at the stage of financial reporting should be able to operate better. This study investigates the implementation problems of the SIMDA Keuangan at the Badan Pengelola Keuangan dan Aset Daerah (BPKAD) in North Sulawesi. This is a qualitative case study. This study found several problems in the implementation of SIMDA application. Those problems are: (a) Lack of system integration and synchronization between SIMDA Keuangan, SIMDA Pendapatan and Bank SulutGo. This can be evidenced by the absence of an efficient, realtime online payment system and the inefficiency of data verification process, (b) Performance and integrity of relevant human resources are still lacking, and (c) The lack of commitment shown by upper level management to maintain and improve the business process of SIMDA Keuangan.Keywords: SIMDA Keuangan, system integration, human resources, commitment of superiors.Abstrak. SIMDA (Sistem Informasi Manajemen Keuangan) Keuangan merupakan persyaratan dan kebutuhan bagi pemerintah provinsi untuk mengelola uang negara. Kehadiran SIMDA Keuangan diharapkan dapat berkontribusi terhadap proses pengelolaan keuangan negara, terutama pada tahap pelaporan keuangan harus dapat berjalan lebih baik. Studi ini menyelidiki masalah implementasi SIMDA Keuangan di Badan Pengelola Keuangan dan Aset Daerah (BPKAD) di Sulawesi Utara. Metodologinya adalah analisis studi kasus dan metode kualitatif. Studi ini menemukan beberapa masalah dalam penerapan aplikasi SIMDA yaitu: (a) Kurangnya integrasi sistem dan sinkronisasi antara SIMDA Keuangan, SIMDA Pendapatan dan Bank SulutGo. Hal ini dapat dilihat melalui tidak adanya sistem pembayaran online yang efisien dan realtime serta ketidakefisienan proses verifikasi data. (b) Kinerja dan integritas sumber daya manusia yang relevan masih kurang, dan (c) Kurangnya komitmen yang ditunjukkan oleh manajemen tingkat atas untuk mempertahankan dan meningkatkan proses bisnis SIMDA Keuangan.Kata kunci: SIMDA Keuangan, integrasi sistem, sumber daya manusia, komitmen atasan.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KUALITAS INFORMASI LAPORAN KEUANGAN PEMERINTAH DAERAH (Studi Empiris Pada SKPD Pemerintah Kabupaten Kepulauan Talaud)
Authors: Modo Sintike Mentari , Saerang David Paul Elia , Poputra Agus Tony 
Published: November 2019

The research was conducted on the basis of the gap between expectations and reality . Hope, by improving the quality of human resources and improvement of legislation in the field of financial management areas, generating financial reports quality information. In fact, the quality of financial reporting information in Talaud Islands District Government showed no significant developments. This is evidenced by the BPK opinion obtained by the Government of Talaud Islands during 2006 through 2015 that Gives Opinion, Unusual, and Fair With Exceptions. Opinion adopted by Talaud Islands raises the question of why the quality of financial reporting information local governments do not progress. Based on the research objective, this study can be categorized in the associative causal type. The location study performed in Talaud Islands District Government. Data used in this study are primary data. Data collection is done by distributing questionnaires to Financial Management (User Administration Budget and Finance Officer) on regional work units (SKPD ) in Talaud Islands District Government. The population used was the financial manager in each SKPD, used as a sample 146 respondents. Data were analyzed using multiple linear regression analysis. The results showed that the Internal Monitoring , Understanding Regulation , Capacity Human Resources (HR), Use of Information Technology, and Organizational Commitment together have a significant effect on the Information Quality Local Government Finance Report (LKPD ), but the partial test results shows that only the Internal Control, Capacity Human Resources ( HR) Organizational commitment has a positive and significant impact on Quality of Information in Local Government Finance Report ( LKPD) . Keywords: Internal Control, Understanding Regulation, Capacity Human Resources, Use of Information Technology, Organizational Commitment, Quality of information in Local Government Financial Report.
IMPLEMENTASI PEDOMAN KENDALI MUTU AUDIT-APARAT PENGAWASAN INTERN PEMERINTAH PADA INSPEKTORAT PROVINSI SULAWESI UTARA
Authors: Mewengkang Sendy J. , Lambey Linda , Saerang David P. E. 
Published: November 2019

The purpose of this research is to know the Implementation of Audit Quality Control – Internal Auditing of Government Apparatus (PKMA-APIP) at Inspectorate of North Sulawesi Province. Procedures in PKMA-APIP consist of Strategic Plan Design, Audit Plan, Audit Action Plan Program Design, Audit Supervision, Audit Process, Audit Report, Feedback on Audit Report and Human Resources they are intended to ensure APIP professionalism implementation in enhancing supervising role quality. This study is a qualitative descriptive research. The result show that the implementation for audit quality control in the Inspectorate of North Sulawesi Province is not optimal and not appropriate perfectly. It is because the audit plan has not been implemented appropriate with PKMA-APIP, human resources are unqualified to fulfill existing workload, monitoring follow up results of the audit conducted by the unit performing the function of reporting is not maximized, unclear job description towards the unit managing administration and human resources, procedures provided in supporting the implementation of the tasks have not yet been implemented adequately and effectively to monitor the implementation of programs and activities (peer review). The monitor is to ensure and guarantee that the audit conducted by the Inspectorate of North Sulawesi Province meet the standard audit. Keywords : Audit, Quality Control, Government Internal Auditors
Identifikasi Faktor-Faktor Penumpukan Realisasi Anggaran Belanja Di Akhir Tahun (Studi Kasus Pada Balai Penelitian Dan Pengembangan Lingkungan Hidup Dan Kehutanan Manado)
Authors: Sudarwati Nina , Karamoy Herman , Pontoh Winston 
Published: November 2019

Abstract. Implementation of the budget is a very important stage in the realization of government programs that have been organized in the National budget. The implementation sometime found difficulties, including the realization of the budget tends to be low in the early years and accumulated at the end of the year. According to Rusqiayati (2014), ideally the realization of the government's budget follows the "S-curve" which is tends to be stable at the beginning of the year, then increased in the mid and stabilized towards the end of the fiscal year. This research aims to identify factors that causing the accumutaed of budget realization in the end of the year at Environment and Forestry Research and Development Institute of Manado. This study is a qualitative case study. The key informants in this research are officers or employees directly involved in financial management, such as the Budget Authority (KPA), Committing Officer (CO), official signing of Warrant Pay (PPSPM), Treasurer, Assistant Treasurer, and Executive Technical Officer ( PTK).The results showed that factors that causing the accumulated of budget realization in the end of the year at Environment and Forestry Research and Development Institute of Manado were budget planning, budget execution, procurement of goods/services, and human resources. Keywords: Accumulation, Budget realization, Thematic Analysis Abstrak Pelaksanaan anggaran merupakan tahap yang sangat peting dalam merealisasikan program dan kegiatan pemerintah yang telah disusun dalam APBN. Dalam pelaksanaan mengalami berbagai kendala, diantaranya realisasi anggaran yang cenderung rendah di awal tahun dan menumpuk di akhir tahun. Menurut Rusqiayati (2014) idealnya, realisasi anggaran pemerintah mengikuti “Kurva S” yaitu cenderung stabil di awal tahun, kemudian meningkat pada pertengahan, dan kembali stabil menjelang akhir tahun anggaran. Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang menyebabkan penumpukan realisasi anggaran di akhir tahun pada Balai Penelitian dan Pengembangan Lingkungan Hidup dan Kehutanan Manado. Penelitian ini menggunakan metode kualitatif studi kasus. Informan kunci penelitian ini adalah pejabat atau pegawai yang terlibat langsung dalam pengelolaan keuangan, seperti Kuasa Pengguna Anggaran (KPA), Pejabat Pembuat Komitmen (PPK), Pejabat Penandatangan Surat Perintah Bayar (PPSPM), Bendahara Pengeluaran, Pembantu Bendahara, dan Pelaksana Teknis Kegiatan (PTK). Hasil penelitian menunjukkan bahwa faktor-faktor yang menyebabkan penumpukan realisasi anggaran belanja di akhir tahun pada Balai Penelitian dan Pengembangan Lingkungan Hidup dan Kehutanan Manado yaitu perencanaan anggaran, pelaksanaan anggaran, pengadaan barang/jasa, dan sumber daya manusia. Kata Kunci : Penumpukan, Realisasi Anggaran Belanja, Analisis Tematik
Analisis Pengelolaan Dana Bantuan Operasional Sekolah (BOS) pada Satuan Pendidikan Dasar di Kota Kotamobagu
Authors: Pontoh Julianti , Ilat Ventje , Manossoh Hendrik 
Published: November 2019

Abstract. Indonesian Government has increased the quality of their education. One of their efforts is by providing School Operational Funding. However, there is a lack of supervision in managing the funding. BPK, BPKP, Inspectorate of North Sulawesi Province and the city of Kotamobagu had not yet conducted any audit on the fundings from 2012 to 2016. BPK has only monitored or controlled the funding whether they are genuinely transferred from central government to School Education Unit and to each school in City of Kotamobagu. From the supervising point of view, nor has School Committee implemented their supervising functions sufficiently. Therefore, this research is intended to investigate such phenomena. This is a qualitative exploratory research. Data were collected by in-depth interviews and document analysis. Data were validated by triangulations: researchers, theory and sources of data. Findings indicate that there are some constraints in managing BOS: supervision, human resources, communication and bureaucracy structure. Those four factors are crucial in relation to manage the funding complying with regulations. Keywords: School Operational Funding Management, Supervision, Human Resources, Communication and Bureaucracy StructureAbstrak. Pemerintah Republik Indonesia berusaha meningkatan pelayanan dan kualitas pendidikan dengan memberikan Bantuan Operasional Sekolah (BOS). Akan tetapi, kurangnya pengawasan dalam pengelolaan dana BOS di Kota Kotamobagu sangatnya tadi lapangan. BPK, BPKP, Inspektorat Propinsi Sulawesi Utara maupun Inspektorat Daerah Kota Kotamobagu belum melakukan audit terhadap pengelolaan dana BOS di Kota Kotamobagu dari tahun 2012 sampai tahun 2016. Selama ini BPK tidak melakukan audit tapi hanya sekedar mengontrol atau memonitoring apakah dana BOS yang disalurkan dari pusat telah diterima oleh Satuan Pendidikan Dasar di Kota Kotamobagu sesuai dengan dana yang ditransferkan ke rekening masing-masing sekolah. Dari segi pengawasan masyarakat, komite sekolah yang seharusnya menjalankan fungsi ini juga tidak melakukannya dengan baik. Oleh sebab itu, penelitian ini bertujuan untuk menganalisis fenomena yang terjadi. Penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan eksploratori (exploratory approach). Data diperoleh melalui wawancara mendalam (indepth interviews), dan dokumentasi (documentation). Sedangkan validitas data yang digunakan adalah triangulasi peneliti, triangulasi teori, dan triangulasi sumber data.Hasil analisis dan pembahasan menyimpulkan bahwa terjadi beberapa hambatan dalam pengelolaan dana BOS. Hambatan-hambatan tersebut adalah masalah-masalah yang terjadi karena pengawasan, sumber daya, komunikasi dan struktur birokrasi. Keempat hal tersebut sangat penting dalam hubungannya dengan pengelolaan dana BOS agar pelaksanannya sesuai dengan regulasi yang ada.Kata Kunci: Pengelolaan Dana BOS, Pengawasan, Sumber Daya, Komunikasi dan Struktur Birokrasi
KONSEP DAN IMPLEMENTASI PENDIDIKAN MULTIKULTURAL DI SEKOLAH DASAR (SD) NEGERI DURENSEWU I
Authors: Salis Husniatin  , Asrul Anan  
Published: November 2019

Research on the concept and implementation of multicultural education for elementary school level students needs to be described and carried out in-depth analysis. Limited learning resources is still related to the implementation of multicultural education for elementary school students. The success or failure in the implementation of Multicultural Education for students in Primary Schools. Thus, this research is focused as follows: 1) What is the concept of multicultural education in SD Negeri Durensewu I Pandaan? 2) How is the implementation of multicultural education in SD Negeri Durensewu I Pandaan ?. 3. Why is success or failure in the implementation of Multicultural Education in Pandaan Durensewu I Primary School?. The results of this study, it was concluded that the concept and implementation of multicultural education in schools was carried out using several approaches, namely the contribution approach, the social action approach and the habituation approach, these were carried out by means of various kinds of activities that existed at school and carried out during teaching and learning activities. In the thematic curriculum applied by schools, there are several subject matter in SD Negeri Durensewu I one of those is elements of multicultural education
تأثير الموسيقى على تشكيل التصميم المعماري في نتاج العمارة العالمي
Authors: Al-Ataabi Mahdi Saleh , Alobaidy Sana Ali Ibrahim 
Published: November 2019

لطالما كان للموسيقى دورها الجوهري في بناء المجتمعات لتصبح دعامة من دعائم المدنية الحديثة , و قد كان للعرب المسلمين باع عظيم في مجال الموسيقى فقسم الفارابي الالحان الى : الملذة , المخيلة , الانفعالية , و قد اشار ابن خلدون بان " احد مؤشرات سقوط الحضارات كان تدني الحس الموسيقي في المجتمع ", و اكد البعض ان الموسيقى هي التي تحول الصورة اللوحة الساكنة في الفراغ الى رؤية موسيقية ومتحركة او رؤية جمالية ذات احساس كامل متحرك و معبر , و نظرا لتعاظم دور الموسيقى و تاثيرها في كل المجالات و اهمها العمارة , تبنى هنا المشكلة العامة التي تتمحور حول العلاقة بين الموسيقى و العمارة مبينة المشكلة الخاصة في انماط تجسيد و تشكيل النص المعماري بتاثير الموسيقى بصورة خاصة , و المشكلة البحثية في وجود فجوة معرفية في العلاقة ما بين الموسيقى و العمارة و مدى تاثير الموسيقى على العمارة و ما يتمخض عنها من نتاج من خلال اخضاع العمارة للموسيقى ليتم تحديد الفقرات التي من الممكن اعتمادها في الارتقاء بمستوى الاداء في التصميم المعماري و نتاج العملية التصميمية. تحدد هدف البحث في توضيح ملامح العلاقة المفاهيمية بين الموسيقى و العمارة و اعتماد مفردات تساعد في تنمية الخطاب الفكري بين المفردتين لاجل ترسيخ تلك العلاقة و تطبيقها على نماذج من العمارة واهم ما توصل البحث اليه هو : اخذ الدلالات الحسية و المعنوية من الموسيقى لتحفز خيال المصمم نحو الخطوط العامة الخاصة بتصميمه, لتحقيق المتعة الفكرية ( الموضوعية) وصولا الى المرئية ( الذاتية ) من خلال عملية ادراكية لتكوين فكرية دلالية من خلال خبرة و تجارب سابقة , و اظهرت النتائج ميل المصمم عند اعتماد الايقاع البطئ الى الخطوط المنحنية و العضوية و الى الخطوط المستقيمة و الزوايا عند اعتماد الايقاع السريع.
Implementasi Website Untuk Meningkatkan Pelayanan Pada Kelurahan
Authors: Muslim Buhori 
Published: November 2019

Along with the rapid progress information technology in every lifer aspect in utility advance technology especcialy to Agung Lawangan village chief as like in given information still doing as manual and needed a delivery information web principle. Methode system develop use is engineering web with the stoge : Costumer Comunication, planning, modeling, contruction and Deployment. The purpose from the website in village chief Agung Lawangan. Produce get dynamic website and easy to update every where. Beside that this website also can be one of medium in Agung Lawangan village chief to preface alternatif media easier to studing for society.