bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of a Web-Based Nonoperative Small Bowel Obstruction Treatment Pathway App
Authors: Lyu Heather , Manca Caitlin , McGrath Casey , Beloff Jennifer , Plaks Nina , Postilnik Anatoly , Borchers Amanda , Diaz Nicasio , McGovern Sean , Havens Joaquim , Kachalia Allen , Landman Adam 
Published: August 2020

Abstract
Objective An electronic pathway for the management of adhesive small bowel obstruction (SBO) was built and implemented on top of the electronic health record. The aims of this study are to describe the development of the electronic pathway and to report early outcomes.
Methods The electronic SBO pathway was designed and implemented at a single institution. All patients admitted to a surgical service with a diagnosis of adhesive SBO were enrolled. Outcomes were compared across three time periods: (1) patients not placed on either pathway from September 2013 through December 2014, (2) patients enrolled in the paper pathway from January 2017 through January 2018, and (3) patients enrolled in the electronic pathway from March through October 2018. The electronic SBO pathway pulls real-time data from the electronic health record to prepopulate the evidence-based algorithm. Outcomes measured included length of stay (LOS), time to surgery, readmission, surgery, and need for bowel resection. Comparative analyses were completed with Pearson's chi-squared, analysis of variance, and Kruskal–Wallis tests.
Results There were 46 patients enrolled in the electronic pathway compared with 93 patients on the paper pathway, and 101 nonpathway patients. Median LOS was lower in both pathway cohorts compared with those not on either pathway (3 days [range 1–11] vs. 3 days [range 1–27] vs. 4 days [range 1–13], p = 0.04). Rates of readmission, surgery, time to surgery, and bowel resection were not significantly different across the three groups.
Conclusion It is feasible to implement and utilize an electronic, evidence-based clinical pathway for adhesive SBOs. Use of the electronic and paper pathways was associated with decreased hospital LOS for patients with adhesive SBOs.
Change in the Dominant Side of Chewing as a Serious Factor for Adjusting the Prophylaxis Strategy for Implant-Supported Fixed Dental Prosthesis of Bounded Lateral Defects
Authors: Zekiy Angelina O. , Bogatov Evgenii A. , Voronov Igor A. , Sarkisyan Martiros S. , Llaka Ernest 
Published: August 2020

Abstract
Objective The main purpose of this article is to study the effect of a change in the dominant side of chewing after prosthetics with fixed structures on implants on the main indicators of osseointegration, adaptation to dentures, and the clinical dental status of patients.
Materials and Methods In a clinical trial, an analysis was made of the adaptation of 64 patients to intraosseous implant-supported fixed dentures and 56 apparently healthy volunteers. The examination complex included determination of the functionally dominant side of chewing, gnathodynamometry and electromyography indicators of masticatory muscles, and radiological osseointegration criteria. The overall treatment outcomes were evaluated using a visual analogue scale and an objective medical questionnaire, “Prognosis of Adaptation to Orthopedic Structures.”
Results Patients were divided into two subgroups: with a change in the dominant side of chewing after completion of orthopaedic treatment (40 cases) and without a change in the dominant side of chewing (24 cases). In the second subgroup of patients, in contrast to the first subgroup, relatively better indicators of gnathodynamometer and electromyography were observed. So, in the first group, gnathodynamometry indicators on the dominant side were 255.7 N and in the second group 225 N after 9 to 12 months. Electromyography indices amounted to (198.5 μV s) to (166.3 μV s) after 9 to 12 months. Bone density remained at the required level, and overall treatment outcomes were higher. Namely, the compact plate of the alveolar ridge was preserved, and the condition of the bone tissue around the implants testified to stable osseointegration. The participation of surface masticatory muscles in adaptation of patients to intraosseous implant-supported fixed orthopaedic structures and the necessity and importance of changing the dominant chewing side for the general outcomes of orthopaedic treatment have been discussed.
Conclusions It has been established that a change in the functionally dominant chewing side is accompanied by relatively unstable indicators of chewing function, which is combined with increased loads on the installed prostheses during 3 to 6 months of adaptation. This must be taken into account when planning an individual patient adaptation complex for dental orthopaedic structures.
Determinants of Categories of TB Retreatment with Special Reference to Sources of Primary Anti-TB Treatment
Authors: Karthikeyan Veerabadran , Ganapathy Kalaiselvan 
Published: August 2020

Abstract
Introduction Retreatment (previously treated) cases are the tuberculosis (TB) patients who have been treated previously with anti-TB drugs for at least a month and who have now been registered for category II anti-TB therapy. Retreatment cases arise due to inadequate and improper treatment of the new TB cases.
Objective The aim of the study is to assess the information regarding sources of previous TB drug exposure and treatment practices leading to retreatment cases (category II) and determinants leading to retreatment.
Material and Methods It was a community-based cross-sectional study of patients registered as retreatment TB cases under revised national TB control program (RNTCP) in the TB unit of Puducherry between October 2013 and September 2014. The study was held between October 2013 and October 2015. Initially the quantitative data were collected and followed by qualitative data. Data were collected by interviewing the patients using a predesigned questionnaire. Data were entered and analyzed by using Epi Info (Version 3.4.3) software package.
Results Out of the 193 study participants, relapse cases were the most common 50.8%, followed by treatment after default cases 23.8%, failure cases 11.9%, and retreatment others 13.5%. There is a significant association between the retreatment categories such as failure, TAD (treatment after default), retreatment others, and ever usage of tobacco (p < 0.05). There is also a significant association between the retreatment categories such as TAD, retreatment others, and ever usage of alcohol (p < 0.05). The sources of previous antitubercular therapy for 90.16% retreatment cases were from government health care facilities under RNTCP, whereas for 9.84% retreatment cases the sources of previous antitubercular treatment were private health care facilities. There is a significant association between public health care facility where patients were previously treated for TB and relapse (p = 0.001) and private health care facility where patients were previously treated for TB and TAD (p = 0.008).
Conclusion As 90% of the patients have utilized the government health services for treatment, it shows the effective functioning of RNTCP-STF (state task force-revised national TB control program) mechanism in Puducherry.
“I’m all that stands between them and chaos:” a monstrous way of ruling in A Song of Ice and Fire
Authors: Kovács Györgyi 
Published: August 2020

AbstractThe article explores Tyrion Lannister’s rule in King’s Landing in the second volume of A Song of Ice and Fire books, A Clash of Kings. In the reception of ASOIAF and the TV show Game of Thrones, Tyrion was considered one of the best rulers, and the TV show ended by making him Hand to a king who delegated the greatest part of ruling to him. The analysis is based on Foucault’s notion of monstrosity in power, which is characterized by a monstrous conduct and includes the excess and potential abuse of power. The article argues that monstrosity in his rule reveals deeper layers in Tyrion’s personality, which is initially suggested to be defined by morality. The article also comes to the conclusion that his morality limits the scope of his monstrous methods, which eventually leads to his fall from power.
The m
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A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor
Authors: Xiao Yiren , Thakkar Kaushik N. , Zhao Hongjuan , Broughton James , Li Yang , Seoane Jose A. , Diep Anh N. , Metzner Thomas J. , von Eyben Rie , Dill David L. , Brooks James D. , Curtis Christina , Leppert John T. , Ye Jiangbin , Peehl Donna M. , Giaccia Amato J. , Sinha Subarna , Rankin Erinn B. 
Published: August 2020

Significance
Here we report a synthetic lethal interaction between the epitranscriptomic modifier FTO and the tumor suppressor VHL. Notably, FTO inhibition reduced the growth of both HIF wild type and HIF-deficient tumors. These findings reveal an epitranscriptomic vulnerability of VHL-deficient cells and identify a potential HIF-independent therapeutic target for ccRCC tumors.
Multiomic blood correlates of genetic risk identify presymptomatic disease alterations
Authors: Wainberg Michael , Magis Andrew T. , Earls John C. , Lovejoy Jennifer C. , Sinnott-Armstrong Nasa , Omenn Gilbert S. , Hood Leroy , Price Nathan D. 
Published: August 2020

Significance
Most diseases do not develop suddenly, but rather involve the gradual malfunction of physiological processes due to genetic and environmental influences. Here, we study blood measurements from 4,905 individuals and find that people at elevated genetic risk for various diseases have hundreds of detectable changes in blood protein and metabolite levels as well as clinical laboratory tests. These changes tend to also be present in people with the disease, suggesting that they represent early signs of physiological dysfunction occurring before the onset of disease symptoms.
A β-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL
Authors: Schubeis Tobias , Le Marchand Tanguy , Daday Csaba , Kopec Wojciech , Tekwani Movellan Kumar , Stanek Jan , Schwarzer Tom S. , Castiglione Kathrin , de Groot Bert L. , Pintacuda Guido , Andreas Loren B. 
Published: August 2020

SignificanceHere we show how AlkL, a minimalistic outer-membrane protein from oil-consuming bacteria, exploits dynamics of extracellular loops to channel substrate across the polysaccharide barrier and into the hydrophobic interior of the outer membrane. This work represents a unique example of a side-by-side atomic-level structure determination by solution NMR in detergents and by solid-state NMR in lipid bilayers, which critically demonstrates the importance of a lipid environment to investigate function. Corroborating our experimental measurements, molecular-dynamics simulations capture substrate transit via lateral openings. The capacity to unravel membrane protein function under near-native conditions, fueled by the latest method developments, opens up a new frontier for their investigation, and provides thereby for improved fundamental insights into biological processes.
One gene, multiple ecological strategies: A biofilm regulator is a capacitor for sustainable diversity
Authors: Mhatre Eisha , Snyder Daniel J. , Sileo Emily , Turner Caroline B. , Buskirk Sean W. , Fernandez Nicolas L. , Neiditch Matthew B. , Waters Christopher M. , Cooper Vaughn S. 
Published: August 2020

SignificanceMany organisms, including bacteria, live in fluctuating environments that require attachment and dispersal. These lifestyle decisions require processing of multiple external signals by several genetic pathways, but how they are integrated is largely unknown. We conducted multiple evolution experiments totaling >20,000 generations withBurkholderia cenocepaciapopulations grown in a model of the biofilm life cycle and identified parallel mutations in one gene,rpfR, that is a conserved central regulator. Because RpfR has multiple sensor and catalytic domains, different mutations can produce different ecological strategies that can coexist and even increase net growth. This study demonstrates that a single gene may coordinate complex life histories in biofilm-dwelling bacteria and that selection in defined environments can reshape niche breadth by single mutations.
Hongkongites, Hong Kongers, Hong Kong Belongers?
Authors: Schulz Ninja , Biewer Carolin , Lehnen Lisa 
Published: August 2020

Abstract
To find empirical evidence for Schneider’s (2007) periodisation for the
emergence of Hong Kong English, Evans (2014, 2015) scrutinised various historical documents, such as newspapers, council proceedings and jury lists. Taking the
increasing use of the terms Hongkonger and Hongkong people during the 1980s as evidence for the
emergence of a new Hong Kong identity, he argued that the Chinese population considered themselves part of the community. This
paper systematises Evans’ (2014) approach by analysing terms denoting ingroup and
outgroup members in English news discourse in Hong Kong from 1903 to 1999. By tracing changes in frequency, reference and
discourse topics associated with the terms, periods of identity reconstructions are uncovered and Schneider’s and Evans’
periodisations reassessed. The study thus contributes to our understanding of the social dynamics in Hong Kong’s history, which
are considered key to the emergence of Hong Kong English.
Language learning grit, achievement, and anxiety among L2 and L3 learners in Russia
Authors: Sudina Ekaterina , Plonsky Luke 
Published: August 2020

Abstract
Although most research into grit – an individual difference that encompasses perseverance and passion for
achieving long-term goals – has taken a domain-general perspective (e.g., Duckworth et al.,
2007), emerging interest in a domain-specific approach to grit (e.g., Clark &
Malecki, 2019) provides the groundwork for research into language learning grit. Expanding upon this nascent line of
research (e.g., Teimouri, Plonsky, & Tabandeh, in press), this exploratory study
supports a two-dimensional factor structure of language learning grit and, given the superior criterion validity of the
perseverance of effort (PE) grit subscale comparable to foreign language anxiety with regard to second (L2) and third (L3)
language achievement and self-rated proficiency among 153 Russian undergraduates, a reconceptualization of – and further research
into – grit as a language-domain-specific construct in second language acquisition (SLA).
The translator as cartographer
Authors: Zhou Leonora Min 
Published: August 2020

Abstract
The concept of a cognitive map has been borrowed from psychology by literary scholars to denote the mental
representation of the spatial layout of (a) storyworld(s). The classic Chinese novel 紅樓夢 Hongloumeng ‘The Story of the Stone’ (also known as
The Dream of the Red Chamber) is particularly well-known for its topographic representation of a storyworld
of self-contained totality and detailed veracity. Using David Hawkes’s English translation of the novel and various materials from
his notebooks, this article demonstrates the translator’s (mental) cartographic effort to conjure up ‘maps in mind’ in response to
the textual spatial cues. I argue that Hawkes’s cognitive maps offer explanations to some translational performances that have
been too readily glossed over as insignificant. The article also aims to chart a new path forward for systematic investigation
into the significance of the translator’s imaginative participation in ‘the world inside the text’, for the sake of an enriched
understanding of translation, both as a product and a process.
Researching the motivation of Spanish to Chinese fansubbers
Authors: Moreno García Luis Damián 
Published: August 2020

Abstract
In recent years, the motivation of translators has attracted attention from TS scholars but there is a clear gap about the Chinese context. This paper explores the motivating factors of a Spanish-Chinese fansubbing group of volunteer translators that constitute a community nicknamed The Burrow. It probes into their perceptions in relation to their task and the public, and hints at the possible link between motivation, collaborative translation, and audiovisual content production by fans. A netnographical method was adopted for data gathering, via two questionnaires, a self-designed open-probe survey (OPS) and a modified version of the Volunteer Function Inventory (VFI) proposed by Clary et al (1998). Most fan translators think of themselves as consumers-producers and show traits similar to those of their readers. They believe producing content by themselves is related to higher motivation and also consider a relation between collaborative translation and higher motivation to exist. Self-determination theory was used for the analysis of motivations, and the emerging key motivating factors were understanding, enhancement and values. Passion and attaining experience were the two most important motivators before starting to fansub, and finding friends and having a volunteering platform were the two key motivating factors after becoming fansubbers.
Different strokes for different folks
Authors: Wehrmeyer Ella , Antunes Sarita 
Published: August 2020

Abstract
Until recently, the translator’s personality was a relatively unexplored area of research, but growing evidence points to
the influence of personality on the translator’s decisions. Although findings are not always statistically significant, empirical research
indicates that professional translators’ profiles differ from that of the local population, and that certain personality types are more
likely to make creative translation choices. This article explores the relationship between personality traits as defined by
the Big Five Inventory (Costa & McCrae 1989), and translation choices as defined by Baker
(2018) and Molina & Hurtado (2002). The findings indicate that professional translators with a dominant neurotic personality
trait are the most creative, whereas those with a dominant conscientious personality trait prefer literal translation choices. However, the
findings also indicate that age and experience are competing variables, both indicating a preference for literal translation.
Tracking mental processes in sight translation
Authors: Płużyczka Monika 
Published: August 2020

Abstract
The article reviews the author’s research on two selected eyetracking parameters, i.e., spatial saccades and pupil
dilation, and their relationship with the mental activity of the translator during sight translation performance. An overview and
discussion of the results of studies conducted in recent years show how we can detect particular mental processes involved in
translation thanks to the analysis of specific saccadic movements. It also points out the advantages and limitations of pupil
dilation in the assessment of the cognitive load. Both eyetracking parameters have been analysed in relation to their
neurobiological determinants.
The early presence and developmental trend of interpreter advantages incognitive flexibility
Authors: Zhao Hongming , Dong Yanping 
Published: August 2020

Abstract
Findings about interpreter advantages in cognitive flexibility have been discrepant. To examine whether task differences
and interpreters’ L2 proficiency contributed to the discrepancy, we tested two groups of university students (interpreting trainees vs.
control participants) with two color-shape switching tasks differing in stimulus valence (univalent vs. bivalent). The results showed that:
(1) only the univalent task detected a switch cost advantage for the interpreter group, indicating the task condition for observing
interpreting trainees’ early advantage in local switching ability (as indexed by switch cost); (2) only the interpreter group with an
advanced L2 proficiency showed a marginally significant mixing cost advantage over the control group, indicating a tendency toward an
advantage in more global and sustained control. These findings suggest tentative explanations for the discrepant results in the literature
and conditions for the presence and development of interpreter advantages in cognitive flexibility.
Feasibility and Acceptability of an Online ECHO Intervention to Expand access to Medications for Treatment of Opioid use Disorder, Psychosocial Treatments and Supports
Authors: Salvador Julie G. , Bhatt Snehal R. , Jacobsohn Vanessa C. , Maley Larissa A. , Alkhafaji Rana S. , Rishel Brakey Heidi , Myers Orrin B. , Sussman Andrew L. 
Published: August 2020

Background Buprenorphine combined with psychosocial support is the standard of care for treatment of opioid use disorder (OUD) in office-based primary care settings. However, uptake of this treatment has been slow due to a number of addressable barriers including providers’ lack of training, staffing concerns, stigma and the need for ongoing support and consultation. This study examined acceptability and feasibility of an online Extensions for Community Healthcare Outcomes (ECHO) model intervention developed to support rural primary care clinics to expand treatment and is part of a larger study tracking the impact of participation in this ECHO on expansion of MOUD in rural primary care. Methods We developed a comprehensive, 12-week online education and mentorship intervention using ECHO aimed at supporting the entire primary care clinic to start or expand treatment using MOUD, psychosocial treatments and recovery supports. We tracked participation and collected feedback using qualitative interviews and post-session questionnaires. Results Sixty-seven primary care staff across 27 rural clinics in New Mexico participated in the study including 32 prescribers and 35 clinic support staff. Average participation was 4/12 sessions. Post-session questionnaires showed positive feedback, including that 95% or more respondents agreed or strongly agreed that the sessions were relevant and improved their confidence. Qualitative interview themes included strong endorsement of the ECHO curriculum. Clinical duties were the most common barrier to attending sessions. Conclusions Engagement of 27 clinics, the range of staff and providers who participated, and positive feedback gathered through survey and qualitative interviews provide evidence of feasibility and acceptability of MOUD ECHO to support expansion of this treatment. However, barriers to participation present an important threat to feasibility. Understanding feasibility and acceptability is an important component of research on the impact of ECHO to expand MOUD treatment.