bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the awareness level of Healthcare workers toward NCOVID-2019 in Pakistan
Authors: Imdad Bushra , Abbas Uzair , Qureshi Ambrina , Mohsin Sehrish , Shireen Amna , Hussain Altaf , Baloch Ramsha Ali , Hussain Niaz , Imdad Nazia 
Published: March 2020

AbstractBackgroundNovel Coronavirus infection disease 2019 (NCOVID-19), caused by the corona virus, was first spotted in Wuhan, city of China, December 2019. The NCOVID-19 virus is spread among individuals through close communication in the form of droplets, not via airborne. Those individuals are at risk of infection who are in close contact with a NCOVID-19 patient or who take care of NCOVID-19 patients. Infection prevention and control measures are critical to prevent the possible spread of any infection in healthcare facilities. Therefore, healthcare workers should be aware of basic knowledge and all procedures concerning prevention and protection from NCOVID-19.ObjectiveThe objective of this study was to evaluate the awareness level of healthcare workers toward NCOVID-2019 in Pakistan.Material and MethodsA questionnaire was generated according to WHO information that was circulated among the healthcare workers of different hospitals and medical institutes of Pakistan. Calculated sample size was 650.ConclusionHealthcare workers have insufficient knowledge of preventive measures and infection control. The authorities must take initiatives on urgent basis to increase the awareness among the healthcare workers and general public also so that the drastic circumstances can be avoided in the developing country like Pakistan.
In-cell destabilization of a homo-dimeric protein complex detected by DEER spectroscopy
Authors: Yang Yin , Chen Shen-Na , Yang Feng , Li Xia-Yan , Feintuch Akiva , Su Xun-Cheng , Goldfarb Daniella 
Published: March 2020

AbstractThe complexity of the cellular medium can affect proteins’ properties and therefore in-cell characterization of proteins is essential. We explored the stability and conformation of BIR1, the first baculoviral IAP repeat domain of X-chromosome-linked inhibitor of apoptosis (XIAP), as a model for a homo-dimer protein in human HeLa cells. We employed double electron-electron resonance (DEER) spectroscopy and labeling with redox stable and rigid Gd3+spin labels at three protein residues, C12 (flexible region), E22C and N28C (part of helical residues 26–31) in the N-terminal region. In contrast to predictions by excluded volume crowding theory, the dimer-monomer dissociation constantKDwas markedly higher in cells than in solution and dilute cell lysate. As expected, this increase was recapitulated under conditions of high salt concentrations given that a conserved salt bridge at the dimer interface is critically required for association. Unexpectedly, however, also the addition of a crowding agent such as Ficoll destabilized the dimer, suggesting that Ficoll forms specific interactions with the monomeric protein. Changes in DEER distance distributions were observed for the E22C site, which displayed reduced conformational freedom in cells. Although overall DEER behaviors at E22C and N28C were compatible with a predicted compaction of disordered protein regions by excluded volume effects, we were unable to reproduce E22C properties in artificially crowded solutions. These results highlight the importance of in-cell DEER measurements to appreciate the complexities of cellularin vivoeffects on protein structures and functions.
Molecular phylogeny of historical micro-invertebrate specimens usingde novosequence assembly
Authors: Orr R.J.S , Sannum M. M. , Boessenkool S. , Di Martino E. , Gordon D.P. , Mello H. , Obst M. , Ramsfjell M.H. , Smith A.M. , Liow L.H. 
Published: March 2020

AbstractResolution of relationships at lower taxonomic levels is crucial for answering many evolutionary questions, and as such, sufficiently varied species representation is vital. This latter goal is not always achievable with relatively fresh samples. To alleviate the difficulties in procuring rarer taxa, we have seen increasing utilization of historical specimens in building molecular phylogenies using high throughput sequencing. This effort, however, has mainly focused on large-bodied or well-studied groups, with small-bodied and under-studied taxa under-prioritized. Here, we present a pipeline that utilizes both historical and contemporary specimens, to increase the resolution of phylogenetic relationships among understudied and small-bodied metazoans, namely, cheilostome bryozoans. In this study, we pioneer sequencing of air-dried bryozoans, utilizing a recent library preparation method for low DNA input. We use thede novomitogenome assembly from the target specimen itself as reference for iterative mapping, and the comparison thereof. In doing so, we present mitochondrial and ribosomal RNA sequences of 43 cheilostomes representing 37 species, including 14 from historical samples ranging from 50 to 149 years old. The inferred phylogenetic relationships of these samples, analyzed together with publicly available sequence data, are shown in a statistically well-supported 65 taxa and 17 genes cheilostome tree. Finally, the methodological success is emphasized by circularizing a total of 27 mitogenomes, seven from historical cheilostome samples. Our study highlights the potential of utilizing DNA from micro-invertebrate specimens stored in natural history collections for resolving phylogenetic relationships between species.
Congenital disorder of glycosylation caused by starting site-specific variant in syntaxin-5
Authors: Linders Peter T.A. , Gerretsen Eveline C.F. , Ashikov Angel , Vals Mari-Anne , de Boer Rinse , Revelo Natalia H. , Arts Richard , Baerenfaenger Melissa , Zijlstra Fokje , Huijben Karin , Raymond Kimiyo , Muru Kai , Fjodorova Olga , Pajusalu Sander , Õunap Katrin , Beest Martin ter , Lefeber Dirk , van den Bogaart Geert 
Published: March 2020

AbstractThe SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein syntaxin-5 (Stx5) is essential for Golgi transport. In humans, theSTX5mRNA encodes two protein isoforms, Stx5 Long (Stx5L) from the first starting methionine and Stx5 Short (Stx5S) from an alternative starting methionine at position 55. In this study, we identify a human disorder caused by a single missense substitution in the second starting methionine (p.M55V), resulting in complete loss of the short isoform. Patients suffer from an early fatal multisystem disease, including severe liver disease, skeletal abnormalities and abnormal glycosylation. Primary human dermal fibroblasts isolated from these patients show defective glycosylation, altered Golgi morphology as measured by electron microscopy, mislocalization of glycosyltransferases, and compromised ER-Golgi trafficking. Measurements of cognate binding SNAREs, based on biotin-synchronizable forms of Stx5 (the RUSH system) and Förster resonance energy transfer (FRET), revealed that the short isoform of Stx5 is essential for intra-Golgi transport. Alternative starting codons of Stx5 are thus linked to human disease, demonstrating that the site of translation initiation is an important new layer of regulating protein trafficking.
Forecasting the dynamics of COVID-19 Pandemic in Top 15 countries in April 2020: ARIMA Model with Machine Learning Approach
Authors: Kumar Pavan , Kalita Himangshu , Patairiya Shashikanta , Sharma Yagya Datt , Nanda Chintan , Rani Meenu , Rahmani Jamal , Bhagavathula Akshaya Srikanth 
Published: March 2020

AbstractWe here predicted some trajectories of COVID-19 in the coming days (until April 30, 2020) using the most advanced Auto-Regressive Integrated Moving Average Model (ARIMA). Our analysis predicted very frightening outcomes, which defines to worsen the conditions in Iran, entire Europe, especially Italy, Spain, and France. While South Korea, after the initial blast, has come to stability, the same goes for the COVID-19 origin country China with more positive recovery cases and confirm to remain stable. The United States of America (USA) will come as a surprise and going to become the epicenter for new cases during the mid-April 2020. Based on our predictions, public health officials should tailor aggressive interventions to grasp the power exponential growth, and rapid infection control measures at hospital levels are urgently needed to curtail the COVID-19 pandemic.
Elective affinities: exploring the matching between entrepreneurs and investors in equity crowdfunding
Authors: Giudici Giancarlo , Guerini Massimiliano , Rossi-Lamastra Cristina 
Published: March 2020

PurposeThe authors investigate whether matchings in equity crowdfunding are more likely to happen if homophily exists between investors and investees. They focus on gender, age and geographical proximity as crucial dimensions of similarity among individuals and thus of homophily. Furthermore, they investigate whether the effect of homophily depends on the risk of opportunism, which investors allegedly attribute to proponents basing on their area of residence.Design/methodology/approachThe authors analyze a hand-collected database of 13 equity crowdfunding campaigns launched by Italian innovative start-ups from January 2013 to June 2016, which includes information about 384 equity crowdfunding investments carried out by 361 different investors.FindingsThe authors find a significant effect of geographical proximity and age similarity in explaining the probability that an investor finances a campaign. Moreover, these effects are particularly relevant if the proponent is located in areas characterized by a high risk of opportunistic behavior. Interestingly enough, they do not detect any significant effect related to gender.Originality/valueIn this paper, the authors have the unique opportunity to analyze a whole market (the Italian market) during three years, from inception (2013–2016), and to collect the identities of the investors in all successful campaigns.
Understanding career advancement of newcomers from perspective of organizational socialization
Authors: He Hui , Gao Junguang , Yan Liumei 
Published: March 2020

Purpose
The purpose of this paper is to investigate how to facilitate newcomers’ career advancement within an organization and diminish their intention to quit from the perspective of socialization. In addition, the moderating role of the type of newcomers on the relationship between socialization tactics and career advancement, and consequently, on the mediating effect of newcomers’ proactive socialization behavior, will be examined.

Design/methodology/approach
Longitudinal survey research was conducted in the tertiary industry in four large cities of China. Regression analysis and bootstrapping method were used to verify the hypothesized relationships.

Findings
Organizational socialization tactics could have positive effects on newcomers’ proactive socialization behavior and promotion prospects. And newcomers’ proactive socialization behavior partly mediates the relationship between organizational socialization tactics and their promotion prospects. The type of newcomers moderates the relationship between proactive socialization behavior and promotion prospects and also the mediation effect of proactive behavior, which says a moderated mediating effect.

Practical implications
Employers should put more value on college recruitment, making good use of social media tools in particular. And they should also select applicants with proactive personality traits. Finally, a series of structured orientation programs should be implemented for all newcomers.

Originality/value
This study contributes evidence for career advancement as one of the distal socialization outcomes, the moderating role of the type of newcomers on the relationship between socialization and career advancement, and the classification as graduates from school and experienced newcomers from other organizations holds significance to examine newcomers’ socialization.
Mentoring is essential but not sufficient: sponsor women for leadership roles
Authors: Singh Swati , Vanka Sita 
Published: March 2020

Purpose
The purpose of the article is to highlight the importance of sponsorship in the career advancement of women and how it can also promote diversity in leadership.

Design/methodology/approach
The paper uses the PwC’s Breakthrough program illustration to demonstrate how the potential of sponsorship can be leveraged to enhance diversity.

Findings
Research in leadership, diversity, and inclusion indicates that the leadership gender gap is a major challenge faced by organizations. Most of the organizations employ mentorship as a strategy for women’s career development. However, it is difficult to assess the measurable impact of this on the careers of women and how it could help in improving diversity in leadership roles. The findings suggest that sponsorship, which is an action-oriented strategy can complement mentoring and bring desired results.

Originality/value
The paper analyses the role of mentoring and sponsorship in the career development of women. The paper also highlights the differences between mentorship and sponsorship. Furthermore, it demonstrates the importance of sponsorship in promoting diversity with the help of PwC’s illustration.
A numerical method for solving optimal control problems via Legendre polynomials
Authors: Gu Yajing , Yan Hongyan , Zhu Yuanguo 
Published: March 2020

Purpose
The purpose of this paper is to propose an iterative Legendre technique to deal with a continuous optimal control problem (OCP).

Design/methodology/approach
For the system in the considered problem, the control variable is a function of the state variables and their derivatives. State variables in the problem are approximated by Legendre expansions as functions of time t. A constant matrix is given to express the derivatives of state variables. Therefore, control variables can be described as functions of time t. After that, the OCP is converted to an unconstrained optimization problem whose decision variables are the unknown coefficients in the Legendre expansions.

Findings
The convergence of the proposed algorithm is proved. Experimental results, which contain the controlled Duffing oscillator problem demonstrate that the proposed technique is faster than existing methods.

Originality/value
Experimental results, which contained the controlled Duffing oscillator problem demonstrate that the proposed technique can be faster while securing exactness.
Finite element modeling of material removal rate in micro-EDM process with and without ultrasonic vibration
Authors: Choubey Mayank , Maity K.P. , Sharma Abhishek 
Published: March 2020

PurposeThis research explores the finite element modeling of the crater and material removal rate (MRR) in micro-electrical discharge machining (micro-EDM) with and without vibration of the workpiece. The application of workpiece vibration in the micro-EDM process improved flushing efficiency and enhanced material removal rate (MRR).Design/methodology/approachIn this work, the two-dimensional axisymmetric finite element method (FEM) has been developed to predict the shape of the crater with and without vibration. The temperature distribution on the workpiece surface with and without vibration has been obtained in the form of the contour plot.FindingsThe MRR obtained from the numerical model revealed that there was an enhancement in MRR in micro-EDM with vibration as compared to without vibration. The effect of process parameters on MRR in micro-EDM with and without is also presented in this work.Originality/valueIn this work, the two-dimensional axisymmetric FEM model has been developed to predict the shape of the crater with and without vibration.
To follow others or be yourself? Social influence in online restaurant reviews
Authors: Li Hengyun , Meng Fang , Jeong Miyoung , Zhang Zili 
Published: March 2020

Purpose
Online reviews are often likely to be socially influenced by prior reviews. This study aims to examine key review and reviewer characteristics which may influence the social influence process.

Design/methodology/approach
Restaurant review data from Yelp.com are analyzed using an ordered logit model and text mining approach.

Findings
This study reveals that prior average review rating exerts a positive influence on subsequent review ratings for the same restaurant, but the effect is attenuated by the variance in existing review ratings. Moreover, social influence is stronger for consumers who had a moderate dining experience or invested less cognitive effort in writing online reviews. Compared to reviewers classified by Yelp as “elite,” non-elite reviewers appear more susceptible to the social influence of prior average review rating.

Practical implications
This study provides guidelines for mitigating the social influence of prior reviews and improving the accuracy of online product/service ratings, which will eventually enhance business and the reputation of online review platforms.

Originality/value
The findings from this study contribute to the electronic word-of-mouth (eWOM) literature and social influence literature in terms of the bidirectional nature of social influence on eWOM.
Profitability of the Northern Sea Route for liquid bulk shipping under post 2020 sulphur regulations
Authors: Keltto Tuomo , Woo Su-Han 
Published: March 2020

PurposeThe purpose of this study is to evaluate the profitability of the Northern Sea Route (NSR) as a shipping lane from the financial perspective of shipping companies under post 2020 sulphur regulations.Design/methodology/approachThis study develops profit estimation model, and the profitability of the NSR is assessed for a Handymax Medium Range (MR) tanker vessel using scenarios in combination with spot market earning levels, the regulation compliance method and destination ports. The required freight rates are calculated to justify the decision of shipowners to transit a tanker from the Baltic spot market to the NSR navigation.FindingsResults suggest that the required freight rates from the Arctic trade to justify the transit to the NSR are higher than the actual agreed rates in the past, which implies low viability of the NSR as a regular shipping lane. It was also found that the required freight rates are affected by the spot market earning levels, compliance method and duration of the voyage.Research limitations/implicationsThis study takes a new approach on assessing the NSR viability by comprehensively assessing the annual profitability and including the spot market trade as an opportunity cost for the NSR shipping. Despite various scenarios used in this study, a sensitivity analysis would be useful for future research.Practical implicationsThis study suggests how much freight rates a shipping company would need to charge if it were to offer tanker shipping services to four major Asian ports while simultaneously operating at the Baltic Sea during the remainder of the year.Originality/valueThis study adopts a market-oriented approach by incorporating both earnings and costs (including opportunity costs) in the profitability model rather than merely analyzing the total cost of shipping via the NSR. This study also analyzes impact of IMO 2020 Sulphur regulation on the NSR profitability.
A comparison of physical anxiety levels in adolescent and young women with polycystic ovary syndrome and in other healthy adolescent and young women in a university hospital, Turkey
Authors: Duman Mesude , Durgun Ozan Yeter 
Published: March 2020

PurposeThis study was conducted to investigate the Social Physique Anxiety (SPA) level in adolescent and young women with polycystic ovarian syndrome (PCOS).Design/methodology/approachThis is a descriptive study. It was conducted in Turkey. The study was conducted from January 1, 2017 to December 31, 2017. It was completed with a total of 150 young women – 75 of them had PCOS and 75 of them were healthy. Study data were collected using demographic information form and Social Physique Anxiety Scale (SPAS).FindingsThe study was found that the adolescent and young women with PCOS had higher subscales and total scores for total SPAS at a statistically significant level than healthy adolescent and young women (p < 0.05).Practice implicationThe findings of this study may be used for planning and implementing interventions in health-care practice such as screening and early treatment of SPA of women with PCOS.Originality/valueIt was found that PCOS in adolescent and young women increased the SPA level. In line with these results, health professionals must be particularly aware of the potential psychosocial and health needs of adolescent and young women with PCOS.
Current developments in money laundering and terrorism financing
Authors: Teichmann Fabian Maximilian Johannes 
Published: March 2020

Purpose
Whilst the existing literature focuses on developing prevention mechanisms for banks, this paper aims to demonstrate the ongoing feasibility of money laundering and financing terrorism undetected. This study thereby reveals that the current anti-money-laundering and anti-terrorism-financing mechanisms can easily be circumvented.

Design/methodology/approach
A three-stage research process was used, including both qualitative and quantitative methods. The empirical findings are based on a qualitative content analysis of 50 informal interviews with illegal financial services providers and 50 formal interviews with compliance experts and law enforcement officers.

Findings
During these interviews, specific methods of financing terrorism and limiting the risks of being prosecuted were discussed. Hence, specific methods of money laundering and terrorism financing have been analyzed.

Research limitations/implications
The findings thus convey only the perspectives of the 100 interviewees, such that generalizability is limited.

Practical implications
The practical implications include suggestions for financial regulators, financial institutions and compliance officers on how to more effectively combat money laundering and terrorism financing. Although the empirical findings are limited to Europe, the results could be applied globally.

Originality/value
This paper reveals new insights about criminals’ actions, which help to develop more effective compliance mechanisms.
Money laundering – the gold method
Authors: Teichmann Fabian Maximilian Johannes , Falker Marie-Christin 
Published: March 2020

Purpose
The purpose of this paper is to demonstrate how illicit funds are laundered by using the gold method in German-speaking European countries.

Design/methodology/approach
To identify approaches to money laundering via gold, 60 semi-standardized interviews with money launderers and compliance officers were conducted. Further, a quantitative survey of 200 compliance officers was administered.

Findings
The gold trade in European German-speaking countries remains extraordinarily suitable for money laundering. In particular, it may be used for placement and layering.

Research limitations/implications
The implications are based on the statements of 60 interviewees, including both money launderers and compliance officers. Thus, the derived results are limited to the perspectives of these 60 persons.

Practical implications
Based on this study’s findings, gaps in the existing anti-money laundering measures are identified. Documenting these inconsistencies should provide compliance officers, law enforcement agencies and legislators with valuable insights into the minds of money launderers.

Originality/value
As this study explores the perspectives of both compliance officers and money launderers, it provides a broad overview of the issues. Most existing literature fails to observe money laundering from the launderers’ perspective, focusing instead on methods to prevent money laundering. Effective prevention requires profound knowledge of how criminals operate. Only by adopting criminals’ perspective can compliance officers effectively spot money-laundering methods.