bluuebunny/crossref_metadata_2025_split huggingface dataset:
Harnessing Ultrasound-Stimulated Phase Change Contrast Agents to Improve Antibiotic Efficacy Against Methicillin-ResistantStaphylococcus aureusBiofilms
Authors: Durham Phillip G. , Sidders Ashelyn E. , Dayton Paul A. , Conlon Brian P. , Papadopoulou Virginie , Rowe Sarah E. 
Published: June 2020

Bacterial biofilms, often associated with chronic infections, respond poorly to antibiotic therapy and frequently require surgical intervention. Biofilms harbor persister cells, metabolically indolent cells, which are tolerant to most conventional antibiotics. In addition, the biofilm matrix can act as a physical barrier, impeding diffusion of antibiotics. Novel therapeutic approaches frequently improve biofilm killing, but usually fail to achieve eradication. Failure to eradicate the biofilm leads to chronic and relapsing infection, associated with major financial healthcare costs and significant morbidity and mortality. We address this problem with a two-pronged strategy using 1) antibiotics that target persister cells and 2) ultrasound-stimulated phase-change contrast agents (US-PCCA), which improve antibiotic penetration.We previously demonstrated that rhamnolipids, produced byPseudomonas aeruginosa, could induce aminoglycoside uptake in gram-positive organisms, leading to persister cell death. We have also shown that US-PCCA can transiently disrupt biological barriers to improve penetration of therapeutic macromolecules. We hypothesized that combining antibiotics which target persister cells with US-PCCA to improve drug penetration could eradicate methicillin resistantS. aureus(MRSA) biofilms. Aminoglycosides alone or in combination with US-PCCA displayed limited efficacy against MRSA biofilms. In contrast, the anti-persister combination of rhamnolipids and aminoglycosides combined with US-PCCA dramatically reduced biofilm viability, frequently culminating in complete eradication of the biofilm. These data demonstrate that biofilm eradication can be achieved using a combined approach of improving drug penetration of therapeutics that target persister cells.
Path to discontinuance of pervasive mobile games: the case of Pokémon Go in Australia
Authors: Butcher Luke , Tucker Oliver , Young Joshua 
Published: June 2020

PurposePervasive mobile games (PMG) expand the game context into the real world, spatially, temporally and socially. The most prominent example to date is Pokémon Go (PGo), which in the first 12 months of its launch achieved over 800 million downloads and huge revenues for Pokémon, its majority owner Nintendo, and its developer Niantic. Like many mobile apps and innovative services, PGo's revenue structure requires continual usage (through in-app purchases and sponsorships) as it is free to download. Thus, as many players discontinued after initial adoption, substantial drops in Nintendo's share price occurred alongside the damage to brand equity. Such a case highlights the need to extend scholarship beyond traditional ‘adoption’ and begin to truly illustrate and explain the consumer behaviour phenomenon of ‘discontinuance’, particularly in the emerging and lucrative domain of PMGs.Design/methodology/approachLike many emerging marketing channels before it, large-scale discontinuance of PGo occurred and still remains unexplained in the academic literature. Herein, we address this shortcoming through a consumer case study methodology analysing a variety of data sources pertaining to PGo in Australia.FindingsThe development of the P2D_PMG model provides a new conceptual framework to illustrate the distinct forms discontinuance manifests in, for the first time. Scholarly rigour of the P2D_PMGs is achieved through validating and extending Soliman and Rinta-Kahila's (2020) framework for ‘discontinuance’ through its five forms. These forms are revealed as access and on-boarding (rejection), disconfirmation and hedonic adaptation (regressive discontinuance), technological, social, third parties, and personal issues (quitting), re-occurrences of hedonic adaptation (temporary), and alternatives and iterations (replacement).Originality/valueConceptual contributions are made in developing a model to explain what drives PMG discontinuance and when it occurs. This is particularly crucial for products with revenue structures built on continual usage, instead of initial adoption. In deriving data from actual players and aggregate user behaviour over an extended time period, the innovative case study methodology validates new discontinuance research in a manner other methods cannot. Managerial implications highlight the importance of CX, alpha/beta testing, promotion and research, gameplay design and collaboration/community engagement.
How does servant leadership influence employees' service innovative behavior? The roles of intrinsic motivation and identification with the leader
Authors: Su Weilin , Lyu Bei , Chen Hui , Zhang Yanzi 
Published: June 2020

PurposeWith the rapid development of the service industry, service innovation has gradually become a hot topic in business today. How to further improve employees' service innovative behaviors has become critical to organizations' survival and success. Servant leadership, as a leadership style characterized by serving others, is closely related to employees' service innovative behaviors. Therefore, the purpose of this study is to develop a theoretical framework to examine the influence of servant leadership on employees' service innovative behavior, the mediating role of intrinsic motivation and the moderating role of identification with the leader.Design/methodology/approachTo test the theoretical model, a multi-time survey method was used to collect data from 381employees from a large high-tech company in Mainland China.FindingsThe results confirm that servant leadership can promote employees' service innovative behavior and intrinsic motivation. Meanwhile, employees' intrinsic motivation partly mediates the influence of servant leadership on their service innovative behavior. Moreover, this mediating relationship is conditional on the moderating role of individual identification with the leader in the path from servant leadership to individual intrinsic motivation.Research limitations/implicationsThe key limitation of this study lies in the representativeness of sample data, which is the convenience of non-probability sampling and self-reported data only from a large high-tech company in China.Practical implicationsThis study not only further verified a promotion factor of individual service innovative behavior from the perspective of leader influence, but also enriched the understanding of the positive influence of servant leadership on employees.Originality/valueThis study is the first to examine the relationships among servant leadership, employees' intrinsic motivation, identification with the leader and service innovative behavior. The results may help to open the “black box” of the relationship between servant leadership and employees' service innovative behavior by introducing their intrinsic motivation. The conclusions also indicate employees' identification with the leader is an important boundary condition among their relationships. Particularly, it not only moderates the relationship between servant leadership and intrinsic motivation, but also moderates the mediating role of intrinsic motivation.
Diversity in the work–life interface: introduction to the special issue
Authors: Beauregard T. Alexandra , Adamson Maria , Kunter Aylin , Miles Lilian , Roper Ian 
Published: June 2020

PurposeThis article serves as an introduction to six articles featured in a special issue on diversity in the work–life interface. This collection of papers contains research that contemplates the work–life interface in different geographic and cultural contexts, that explores the work–life experiences of minority, marginalized and/or underresearched groups of workers and that takes into account diverse arrangements made to fulfill both work and nonwork responsibilities.Design/methodology/approachThis introductory article first summarizes some of the emerging research in this area, introduces the papers in this special issue and links them to these themes and ends with highlighting the importance of using an intersectional lens in future investigations of the work–life interface.FindingsThese six articles provide empirically based insights, as well as new theoretical considerations for studying the interface between paid work and personal life roles. Compelling new research directions are identified.Originality/valueIntroducing the new articles in this special issue and reviewing recent research in this area brings together the work–life interface scholarship and diversity management studies and points to the necessity for future investigations to take an intersectional and contextualized approach to their subject matter.
Women’s re-entry after a career break: Efficacy of support programs
Authors: Kaushiva Pavni , Joshi Chetan 
Published: June 2020

PurposeThere is a recent organizational focus on increasing and managing gender diversity with stress on supportive policies for working mothers. The purpose of this paper is to examine the effect of one such supportive policy (i.e. completion of company-initiated internship programs) designed to help women return to the workforce post a career break.Design/methodology/approachThe study uses an experimental design to compare the evaluation of a woman applicant who has a career break with the evaluation of a woman applicant who has completed a support program after a career break. Variance in the evaluation of the applicant on the parameters – educational qualification, professional qualification, fit with job description and invite for an interview is tested. The study also examines the effect of individuals’ neosexist attitude on their evaluation of the applicant. Data were collected from 109 participants having an average age of thirty-two years (SD = 5.97), and average work experience of 9 years (SD = 5.20).FindingsResults show that completion of a support program, as well as neosexism, have a main effect on the evaluation of job fit.Practical implicationsResults have implications for employee-training programs, as well as development programs for women re-entering the workforce post a career break.Originality/valueThis paper is the first to study the efficacy of internship programs for re-entry of women, started by various multi-national companies in India. It extends the application of neosexism to such initiatives, which are not affirmative action, highlighting the changing nature of sexism.
Digitization of manufacturing: the role of external search
Authors: Lorenz Rafael , Benninghaus Christoph , Friedli Thomas , Netland Torbjørn H. 
Published: June 2020

PurposeManufacturers seek to innovate and improve processes using new digital technologies. However, knowledge about these new technologies often resides outside a firm's boundaries. The authors draw on the concept of absorptive capacity and the literature on open innovation to explore the role of external search in the digitization of manufacturing.Design/methodology/approachThe authors developed and distributed a survey to manufacturing firms in Switzerland, for which 151 complete responses were received from senior managers. The authors used multiple linear regressions to study the relations among the breadth and depth of external search, firms' adoption of digital technologies and operational performance outcomes.FindingsExternal search depth was found to relate positively to higher adoption of computing technologies and shop floor connectivity technologies. No significant correlation was found between external search breadth and firms' adoption of digital technologies. Regarding performance outcomes, there is some evidence that increased adoption of digital technologies relates positively to higher volume flexibility, but not to increased production cost competitiveness.Practical implicationsManufacturing firms that aim to digitize their processes can benefit from inbound open process innovation, but its utility varies for different clusters of digital technologies. Generally, the findings suggest that firms should build strong ties with a few external knowledge partners rather than surface relations with many.Originality/valueThis study contributes to the growing literature on the digitization of manufacturing with an analysis of the relation between firms' external search and their adoption of digital technologies. It adds early empirical insights to the literature on open process innovation.
Nation branding, cultural identity and political polarization – an exploratory framework
Authors: Vecchi Alessandra , Silva Emmanuel Sirimal , Jimenez Angel Lina Maria 
Published: June 2020

PurposeThe objective of this research is to propose a framework which is apt to assess how a nation branding campaign could promote cultural identity by ultimately curbing political polarization.Design/methodology/approachBy relying on a multidisciplinary approach that blends theoretical constructs from different fields the methodology is based on a mixed-method approach whereby the qualitative data stemming from a set of interviews with key-informants is coupled by a survey of Colombian citizens in order to gain in-depth insights over the impact of nation branding on political polarization.FindingsFrom the findings, it emerges that a campaign based on nation branding and targeting domestic citizens could curb political polarization within Colombia, by also fostering cultural identity.Research limitations/implicationsThe study considers only Colombia. To fully assess the robustness of the framework it would be useful to extend the analysis to a broader range of countries and to a wider set of domestic issues.Practical implicationsThe research not only provides in-depth insights on how nation branding can be used effectively in order to curb political polarization but also practical guidance on how a nation branding campaign can be effectively designed. The findings are relevant to policy-makers that have the opportunity to implement informed and educated nation branding campaigns not just overseas, but also to strategically address important domestic issues by engaging the domestic stakeholders.Originality/valueWhile country branding has been extensively investigated within the context of international business, we have a relatively limited understanding of its domestic impact. In contrast to traditional country branding literature, this paper aims to theoretically advance our understanding of nation branding and its effect on political polarization, as well as gauging its impact on cultural identity.
Academic entrepreneurship intentions: a systematic literature review
Authors: Neves Sara , Brito Carlos 
Published: June 2020

PurposeThe objective of this research is to have an up-to-date and comprehensive assessment of the current knowledge regarding the variables that encourage the individuals, within the academic community, to get involved in knowledge exploitation activities. It is influenced by the observation that there is a need for more systematic scrutiny of micro-level processes to deepen our understanding of academic entrepreneurship (Balven et al., 2018; Wright and Phan, 2018). The study proposes to answer to ‘What are the drivers of academic entrepreneurial intentions?’ and ‘What are the emerging topics for future research?’Design/methodology/approachThe paper follows a Systematic Literature Review process (Tranfield et al., 2003) and adopts a four-step process format from previous literature reviews within the entrepreneurship context (Miller et al., 2018). From the results within Scopus and Web of Science databases, this research selected, evaluated, summarised and synthesised 66 relevant papers.FindingsThis study provides a factor-listed representation of the individual, organisational and institutional variables that should be considered in the strategies defined by the university. Moreover, the study concludes that the push factors behind the intentions are multiple, context-dependent, hierarchy-dependent, heterogeneous and, at the same time, dependent on each other and against each other. Lastly, the study contributes to academic entrepreneurship literature, especially entrepreneurial intention literature, which has recently received more researchers' attention.Originality/valueThe study corroborates that the individual factors, directly and indirectly via Theory of Planned Behaviour, strongly impact the academics' intentions. While the focus of the papers under review was an in-depth analysis of a selected group of factors, this SLR sought to compile the factors that were identified and provide a broader picture of all those factors to be considered by the university management. It contributes to the identification and clustering of the drivers that encourage academics to engage in knowledge valorisation activities, differentiating them by activity. For the practitioners, this list can be used by university managers, TTOs and department managers, and policymakers to guide questionnaires or interviews to analyse their academics' intentions and adequately support its academic engagement strategy. Lastly, this study also suggests worthwhile avenues for future research.
Corporate philanthropic giving and sustainable development
Authors: Yu Hui-Cheng 
Published: June 2020

PurposeThis paper aims to use the social impact hypothesis and the shift of focus hypothesis to examine what drives controversial industries to make philanthropic donations: sustainable development, which can in turn lead to higher firm performance or a better corporate image.Design/methodology/approachThis study employed a sample of Chinese firms from 2008–2015 and conducted regression analysis to explore the motivations behind corporate philanthropy.FindingsPhilanthropic giving is positively and significantly related to all indicators of firm performance; the interaction term of controversial industries and philanthropic giving is also positively and significantly related to firm performance. The empirical evidence supports the social impact hypothesis.Practical implicationsThe empirical evidence shows that firms engage in philanthropic giving, mainly in pursuit of their own interests. Hence, managers should consider the inherent characteristics of the company and then combine social interests with their economic interests to design a philanthropic strategy of their own, which can in turn contribute to sustainable development.Originality/valueThis paper empirically confirms that the social impact hypothesis holds for the philanthropic activities of Chinese firms. This is a rare finding in related studies.
Roles of strategic orientations in radical product innovation
Authors: Lin Chih-Wei , Cheng Li Keng , Wu Lei-Yu 
Published: June 2020

PurposeBecause of relatively short product life cycles, radical product innovation has more significant influences on firms' competitive advantages in dynamic environments. Past studies identified various cultural characteristics of a firm, which are key drivers of developing radical product innovation on an ongoing basis. However, few studies have investigated the interaction between organizational culture and external market feedback in developing radical product innovation.Design/methodology/approachTo address the identified research gaps, this empirical research began by presenting conceptual foundations that lead to the hypothesized model and then analyzed survey data from 201 original equipment manufacturer suppliers in search of evidence supporting the hypotheses.FindingsThe results suggested that a supplier's entrepreneurial orientation and long-term orientation significantly and positively affected proactive market orientation, with proactive market orientation significantly and positively correlated with radical product innovation. The study confirmed that a proactive market orientation is essential in order for entrepreneurial orientation and long-term orientation to affect radical product innovation. Additionally, this study found that supplier–customer electronic integration has a moderating effect on proactive market orientation and radical product innovation.Originality/valueRadical product innovation is a topic of great interest for both academia and industry, yet a comprehensive conceptual framework for its antecedents is still lacking. To fill this theoretical gap, the present study extended the studies on radical product innovation and examined the relationship between different strategic orientation types in terms of supplier–customer strategic behaviors to determine how suppliers enhance radical product innovation.
Fresh properties and compressive strength of self compacting concrete with fines aggregate replacement using red brick powder and rice husk ash
Authors: Prayuda Hakas , Monika Fanny , Cahyati Martyana Dwi 
Published: June 2020

Purpose
This study aims to discuss the results of fresh properties and compressive strength of self-compacting concrete using ingredients added red brick powder as a fine aggregate substitute. The results of the study were compared with the properties of fresh properties and compressive strength with ingredients added by rice husk ash, which is also a fine aggregate substitute. In addition, the initial compressive strength of each of these variations was also examined to accelerate the completion time of construction projects using self-compacting concrete.

Design/methodology/approach
This research was conducted in a laboratory by testing the characteristics of fresh and hardened properties of self-compacting concrete.

Findings
Fresh properties testing is carried out in the form of V-funnel, flow table, J-ring and L-box where all specimens produce quite varied flow rates. Compressive strength was estimated at ages 3, 7, 14 and 28 days with cylindrical specimens with a diameter of 150 mm and a height of 300 mm. The variation of fine aggregate substitutes used is 20, 40 and 60 per cent.

Originality/value
From the results of the compressive strength, it can be concluded that the added material is categorized as self-compacting concrete with high initial compressive strength, while at 28 days, the compressive strength test results are categorized as high-strength self-compacting concrete.
Vitamin D and stress urinary incontinence in pregnancy: a cross‐sectional study
Authors: Stafne SN , Mørkved S , Gustafsson MK , Syversen U , Stunes AK , Salvesen KÅ , Johannessen HH 
Published: June 2020

ObjectiveTo assess the association between levels of vitamin D and urinary incontinence (UI) in pregnancy.DesignA cross‐sectional study. Secondary analysis of a randomised controlled trial.SettingTwo university hospitals in Norway.PopulationA total of 851 healthy, pregnant women >18 years in gestational weeks 18–22 with a singleton live fetus.MethodsData on UI were collected from a questionnaire at inclusion and serum analysis of 25‐hydroxy vitamin D (25(OH)D) was performed. Univariable and multivariable logistic regression analyses were applied to study associations between exposure and outcomes.Main outcome measuresPrevalence of self‐reported UI, stress (SUI) and urge (UUI) or mixed UI.ResultsIn total, 230/851 (27%) of the participants were vitamin D insufficient (25(OH)D <50 nmol/l) and 42% reported to have any UI. Women with 25(OH)D <50 nmol/l were more likely to report any UI (P = 0.03) and SUI (P < 0.01) compared with women with 25(OH)D ≥50 nmol/l. In a univariable logistic regression analysis, serum levels of 25(OH)D <50 nmol/l was associated with increased risk of any UI (odds ratio [OR] 1.5 with 95% CI 1.0–2.1), SUI only (OR 1.7, 95% CI 1.2–2.4), but not mixed UI or UUI only (OR 0.8, 95% CI 0.5–1.5). In a multivariable logistic regression model, serum levels of 25(OH)D <50 nmol/l were associated with a higher risk of experiencing SUI only (OR 1.5, 95% CI 1.1–2.2).ConclusionsSerum 25(OH)D <50 nmol/l was associated with increased risk of any UI, and SUI in particular.Tweetable abstractLow levels of vitamin D are associated with increased risk of urinary incontinence in pregnancy.