bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of different airway tests to determine difficult intubation in apparently normal adult patients: A prospective observational study
Authors: EL-Radaideh Khaled , Dheeb Ehab , Shboul Hamzeh , Garaibeh Saif , Bataineh Adel , Khraise Wail , Radaideh Basil EL 
Published: June 2020

Abstract
Background
It is important to perform preoperative airway tests for prediction of difficult intubations because inadequate maintenance of a patient’s airway is still the major cause of anesthesia-related morbidity and mortality.
Methods
We conducted this study to determine which airway test, or combination of airway tests, was most clinically useful. One hundred sixty adult patients underwent preoperative assessments of the mandible protrusion test (MPT), thyromental (TMD) and sternomental (SMD) distances, inter-incisor gap (IIG), and the modified Mallampati tests with tongue protrusion (MMT-TP) and without tongue protrusion (MMT-NTP). Grade C on the MPT, TMD ≤ 6 cm, SMD ≤ 12 cm, and MMT grades III and IV were considered to be predictors of difficult tracheal intubations. A modified Cormack-Lehane grading (MCLG) of laryngoscopic views with backward, upward, and right-sided pressure on the thyroid and cricoid cartilages (BURP) maneuver was also documented, with grades 2B, 3, and 4 considered to be difficult airways for intubation.
Results
Fifteen patients (9.4%) were classified as MCLG 2B, 3, and 4, with age significantly associated with the MCLG grade (P = 0.028). The sensitivity and Youden's index of MMT-TP were found to be the lowest (40% and 0.29, respectively). The MPT was the most accurate and specific test (90.63% and 95.17%, respectively), with the highest PPV (50%), Youden's index (0.42), and area under the curve (AUC) (0.781). Bivariant analysis of MPT and the t-test of the mean TMDs and SMDs revealed significant associations between these airway tests and the difficulty of intubation (P values: < 0.001, 0.02, < 0.01, respectively).
Conclusion
The MPT, with its highest accuracy, specificity, positive predictive value, and good sensitivity may be used as a routine screening test for preoperative prediction of difficult tracheal intubations.
Synthesis, Biological Evaluation and Molecular Modeling Studies of Novel C (7) Modified Analogues of Chrysin
Authors: Ramesh Pulabala , Rao Vankadari Srinivasa , Reddy Puchakayala Muralidhar , Babu Katragadda Suresh , Rao Mutheneni Srinivasa 
Published: June 2020

Background::
Most of the currently available pharmaceutical drugs are either natural
products or analogues of natural products. Flavonoids are plant based natural polyphenolic
compounds which exhibit a wide range of biological activities. Chrysin, a natural flavone, exhibits
several biological activities like antiallergic, anti-inflammatory and anticancer. Many efforts were
made to enhance the biological activity of chrysin. In continuation of our work on synthetic
modifications of chrysin, amino-alcohol containing heterocyclic moiety is linked to chrysin at C (7)
position to enhance its biological activity.

Methods::
A series of new C (7) modified analogues of chrysin (3a-k) have been designed and
synthesized in two steps. Chrysin, on reacting with epichlorohydrin in the presence of K2CO3 in
DMF gave epoxide (2) which was made to react with cyclic secondary amines in the presence of
LiBr to form the designed products (3a-k). All the synthesized compounds (3a-k) were well
characterized by 1H NMR, 13C NMR and mass spectral data. The synthesized analogues (3a-k) were
screened for their in vitro biological activities against a panel of bacterial and fungal strains.
Molecular docking studies were also performed on these compounds with E. coli FabH (1HNJ) and
S. cerevisiae (5EQB) enzymes, to support the observed biological activities.

Results::
A series of new 2-hydroxy 3-amino chrysin derivatives (3a-k) were synthesized in two
steps, starting with chrysin and their structures were characterized by spectral analysis. In vitro
biological activities of these analogues against a panel of bacterial and fungal strains indicated that
some of the derivatives manifested significant activities compared to standard drugs. Molecular
docking and binding energy values were also correlated with experimental antimicrobial screening
results. Lipinski’s “rule of five” is also obeyed by these analogues (3a-k) and exhibit drug-likeness.

Conclusion::
In the present study, a series of new C (7) modified chrysin analogues (3a-k) were
synthesized and tested for their in vitro antimicrobial activities. These biological studies indicated
that some of the derivatives exhibited moderate to good antimicrobial activities compared to
standard drugs. Molecular docking studies performed on these compounds correlated with the
experimental antimicrobial activities. The results obtained in the study will be useful in establishing
new drug entities to control the pathogenic epidemics.
Identification of Novel Phyto-chemicals from Ocimum basilicum for the Treatment of Parkinson’s Disease using In Silico Approach
Authors: Mubashir Nageen , Fatima Rida , Naeem Sadaf 
Published: June 2020

Background:
Parkinson’s disease is characterized by decreased level of dopaminergic
neurotransmitters and this decrease is due to the degradation of dopamine by protein Monoamine
Oxidase B (MAO-B). In order to treat Parkinson’s disease, MAO-B should be inhibited.

Objective:
To find out the novel phytochemicals from plant Ocimum basilicum that can inhibit
MAO-B by using the in silico methods.

Methods:
The data of chemical constituents from plant Ocimum basilicum was collected and inhibitory
activity of these phytochemicals was then predicted by using the Structure-Based (SB)
and Ligand-Based Virtual Screening (LBVS) methods. Molecular docking, one of the common
Structure-Based Virtual Screening method, has been used during this search. Traditionally, molecular
docking is used to predict the orientation and binding affinity of the ligand within the active
site of the protein. Molegro Virtual Docker (MVD) software has been used for this purpose. On the
other hand, Random Forest Model, one of the LBVS method, has also been used to predict the activity
of these chemical constituents of Ocimum basilicum against the MAO-B.

Results:
During the docking studies, all the 108 compounds found in Ocimum basilicum were
docked within the active site of MAO-B (PDB code: 4A79) out of which, 57 compounds successfully
formed the hydrogen bond with tyr 435, a crucial amino acid for the biological activity of the
enzyme. Rutin (-182.976 Kcal/mol), Luteolin (-163.171 Kcal/mol), Eriodictyol-7-O-glucoside (-
160.13 Kcal/mol), Rosmarinic acid (-133.484 Kcal/mol) and Isoquercitrin (-131.493 Kcal/mol) are
among the top hits with the highest MolDock score along with hydrogen interaction with tyr 435.
Using the RF model, ten compounds out of 108 chemical constituent of Ocimum basilicum were
predicted to be active, Apigenin (1.0), Eriodictyol (1.0), Orientin (0.876), Kaempferol (0.8536),
Luteolin (0.813953) and Rosmarinic-Acid (0.7738095) are predicted to be most active with the
highest RF score.

Conclusion:
The comparison of the two screening methods show that the ten compounds that were
predicted to be active by the RF model, are also found in top hits of docking studies with the highest
score. The top hits obtained during this study are predicted to be the inhibitor of MAO-B, thus,
could be used further for the development of drugs for the treatment of Parkinson’s disease (PD).
Ionic Liquids: Review of their Current and Future Industrial Applications and their Potential Environmental Impact
Authors: Pešić Jovana , Watson Malcolm , Papović Snežana , Vraneš Milan 
Published: June 2020

Background:
Over the last two decades, thousands of scientific papers and many patents have
been written relating to applications of ionic liquids, a family of compounds that garnered such huge
interest due to their reputation as "green chemicals". This work reviews the recent literature to investigate
the progress ionic liquids have made in their transition from academia to full-scale application in a
variety of industries.

Methods:
For this review, keywords related to ionic liquids and their possible applications were used to
search patent databases such as Google patents. The recent patents thus discovered were tabulated and
sorted by application, and the most significant patents were identified. For each application of ionic liquids
identified in the patent search, an additional review of the recent scientific literature was carried out,
focussing on the relevant ionic liquids and their potential environmental impact.

Results:
Patents involving ionic liquids were found for various industrial applications, including in
chemical industry production technologies, nanotechnology, gas storage and environmental remediation.
Despite the widespread interest of the chemical industry, which hopes to improve the environmental
sustainability of their technologies by utilising ionic liquids, to date, only a handful of full-scale processes
which utilise ionic liquids have been successfully commercialised. That said, a large number of pilot
studies have been carried out in recent years, and 62 patents and 270 scientific texts are summarised
herein and other industrial applications are also approaching the market.

Conclusion:
The properties of ionic liquids inhibit their entry into the atmosphere. However, their annual production is
expected to increase drastically, raising urgent questions about their environmental impact, especially in water bodies.
More research is thus required to identify and mitigate any risks ionic liquids might pose to the environment.
Anaplastic Large Cell Lymphoma ALK-Negative: About a Rare Pediatric Case Report
Authors: Ouidad Louachama , Meriem Elbaz , Jamila El Houdzi 
Published: June 2020

Introduction:
Anaplastic Large Cell Lymphomas (ALCL) are rare in childhood but clinically aggressive. The contemporary World Health Organization (WHO) classification of hematologic malignancies recognizes two distinct subtypes of systemic ALCL: Anaplastic Lymphoma Kinase (ALK)-negative, and ALK-positive.

Case report:
We report a rare pediatric observation of cutaneous nodule revealing an Anaplastic Large Cell Lymphoma (ALCL) ALK - cutaneous, muscular and ganglionic. It was classified according to who classification, treated by polychemotherapy with good outcome.

Conclusion:
ALCL encompasses several distinct clinicopathologic entities with unique genomic under printing. This rare pediatric observation of ALCL presents a new discussion on a pathology still incompletely known.
Construction of Shared OCCA Model Based on Mobile Agent Technology
Authors: Zhao Jun , Sheng Tingyu 
Published: June 2020

Background:
The Open Cloud Computing Alliance (OCCA) strives for more Cloud
Computing Service Providers (CCSP) to join the alliance. OCCA only requires CCSP to provide
virtual computing resources and does not care about the methods of the underlying implementation,
which leads the open-source cloud computing to a larger scale and more efficient. Due to the differences
in service modes and service categories, the cloud computing platforms formed by CCSP are
heterogeneous. How to implement tasks across platforms and ensure the quality of migration are the
key issue for sharing the OCCA platform.

Methods:
The Mobile Agent technology based on a domain is introduced. User tasks are encapsulated
into Mobile agent packets by domain client, which realizes the migration of user tasks from
one platform to another, and makes it possible to interoperate between OCCA virtual machines. To
ensure the service quality of OCCA better, a five-layer logical model of R-OCCA with high commercial
availability is proposed, which defines the service content of each layer and gives the setting
of key parameters. This paper introduces the architectural composition and operational mechanism
of the model, which carries out a qualitative analysis of the model, and establishes an experimental
prototype to verify the feasibility of the model on the virtual machine platform.

Results:
Experiments show that it is feasible to implement Cloud Computing Alliance among cloud
computing platforms through Mobile Agent under the existing technical conditions.

Conclusion:
To better guarantee the quality of OCCA service, a five-level R-OCCA logic model with
strong commercial availability is proposed. The service content of each level is defined and the key parameters
are given. From the CCSP income, the rationality of the model set is explained. The feasibility of the
model was analyzed. The architectural composition and operational mechanisms of the model are introduced.
The performance of the model was also analyzed.
Embodied Conversational Agent Appearance for Health Assessment of Older Adults: Explorative Study
Authors: ter Stal Silke , Broekhuis Marijke , van Velsen Lex , Hermens Hermie , Tabak Monique 
Published: June 2020

Background
Embodied conversational agents (ECAs) have great potential for health apps but are rarely investigated as part of such apps. To promote the uptake of health apps, we need to understand how the design of ECAs can influence the preferences, motivation, and behavior of users.

Objective
This is one of the first studies that investigates how the appearance of an ECA implemented within a health app affects users’ likeliness of following agent advice, their perception of agent characteristics, and their feeling of rapport. In addition, we assessed usability and intention to use.

Methods
The ECA was implemented within a frailty assessment app in which three health questionnaires were translated into agent dialogues. In a within-subject experiment, questionnaire dialogues were randomly offered by a young female agent or an older male agent. Participants were asked to think aloud during interaction. Afterward, they rated the likeliness of following the agent’s advice, agent characteristics, rapport, usability, and intention to use and participated in a semistructured interview.

Results
A total of 20 older adults (72.2 [SD 3.5] years) participated. The older male agent was perceived as more authoritative than the young female agent (P=.03), but no other differences were found. The app scored high on usability (median 6.1) and intention to use (median 6.0). Participants indicated they did not see an added value of the agent to the health app.

Conclusions
Agent age and gender little influence users’ impressions after short interaction but remain important at first glance to lower the threshold to interact with the agent. Thus, it is important to take the design of ECAs into account when implementing them into health apps.
POLÍTICA FISCAL DISCRECIONAL EN BRASIL, 1995-2017: DESCOMPOSICIÓN Y EVOLUCIÓN
Authors: Santos de Oliveira Pontes Amanda , Cabral de Lourenço André Luís 
Published: June 2020

<p>Este artículo tiene como objetivo evaluar la orientación general (expansionista o contraccionista) del componente discrecional de la política fiscal brasileña en el periodo 1995-2017, así como verificar su posición respecto al ciclo económico (procíclica o anticíclica). Con este fin, proponemos y aplicamos una nueva metodología para separar el impulso fiscal discrecional de la parte del resultado fiscal que se obtiene de la activación de los estabilizadores fiscales automáticos. Concluimos que la política fiscal: 1) generó una posición mayormente procíclica (desestabilizadora) de su componente discrecional, lo que la llevó a amplificar en lugar de amortiguar los ciclos económicos; 2) no pudo evitar que la relación deuda pública/PIB entrase en una trayectoria insostenible al final del periodo. Se hacen algunas sugerencias para mejorar su rendimiento.</p><p><strong> </strong></p><p align="center">DISCRETIONARY FISCAL POLICY IN BRAZIL, 1995-2017: DECOMPOSITION AND EVOLUTION</p><p align="center"><strong>ABSTRACT</strong><strong></strong></p>This article aims to evaluate the general (expansionist or contractionist) orientation of the discretionary component of Brazilian fiscal policy in the period 1995-2017, as well as to verify its position in relation to the economic cycle (procyclical or anticyclical). To this end, it proposes and applies a new methodology to separate the discretionary fiscal impulse from the part of the fiscal result arising from the operation of automatic fiscal stabilizers. It concludes that fiscal policy: 1) generated a mostly procyclical (destabilizing) position of its discretionary component, leading it to amplify rather than dampen economic cycles; 2) failed to prevent the public debt/GDP ratio from entering the unsustainable path at the end of the period. Suggestions are made to improve its performance.
Selecting the Power Transformers Rated for 10(6)/0.4 kv Substations Taking into Account the Influence of Nonlinear Load
Authors: Fokeev A. E. , Atrahmanov A. A. , Dautov R. R. 
Published: June 2020

Рассмотрены факторы, влияющие на выбор мощности силовых трансформаторов для подстанций напряжением 10(6)/0,4 кВ. Приведен обзор методов, позволяющих оценить допустимый уровень загрузки силовых трансформаторов при несинусоидальном характере тока нагрузки. Сформулированы рекомендации по выбору расчетного коэффициента загрузки силовых трансформаторов в зависимости от конструкции трансформатора, эксплуатационных характеристик, принятого режима резервирования и доли ответственных потребителей электрической энергии. Предложен алгоритм выбора мощности силовых трансформаторов с учетом влияния несинусоидальных токов нагрузки, предполагающий использование коэффициента снижения допустимой нагрузки. Получены зависимости коэффициента снижения допустимой нагрузки от доли полной мощности нелинейных потребителей при различном гармоническом составе тока нагрузки. Установлено, что для рассматриваемых гармонических составов тока нагрузки при изменении доли полной мощности нелинейной нагрузки от 0 до 100 % значения коэффициента снижения допустимой нагрузки изменяются в пределах 1,0…0,712. Проанализированы результаты выбора номинальной мощности силовых трансформаторов по предложенному алгоритму при различных режимах резервирования (различных значениях расчетного коэффициента загрузки). Выбор мощности силовых трансформаторов производился для трех типовых объектов, характеризуемых различным гармоническим составом тока нагрузки, при изменении доли полной мощности нелинейных потребителей от 0 до 100 %. Установлено, что для обеспечения нормативного срока службы силовых трансформаторов в рассматриваемых случаях их номинальная мощность должна быть увеличена на 25…60 %.Выбор мощности силовых трансформаторов с учетом влияния нелинейной нагрузки целесообразно осуществлять с использованием сведений о гармоническом составе тока нагрузки. Для этого на стадии расчета электрических нагрузок требуется определение расчетной полной мощности электроприемников, имеющих нелинейную вольт-амперную характеристику, и гармонического состава тока нагрузки.Предложенный алгоритм выбора мощности силовых трансформаторов может быть использован в составе методики расчета электрических нагрузок и выбора силового электрооборудования при проектировании трансформаторных подстанций для промышленных объектов, инфраструктурных объектов, жилых и общественных зданий.
Conversación con Leonardo Padura a propósito del tema de esta edición de la revista: exilios, refugio, destierro… y viajes
Authors: Castiglioni Ruben Daniel , Ballester José Vicente , Lopes Luiz Gonzaga 
Published: June 2020

Entrevista com Leonardo Padura, consagrado autor de, entre otras obras, La novela de mi vida (2001), La neblina del ayer (2005), El hombre que amaba a los perros (2009) y Herejes (2013).
Frequency Controlled Noise Cancellation for Audio and Hearing Purposes
Authors: O. Abid Noor Ali 
Published: June 2020

Methods for hearing aids sought to compensate for loss in hearing by amplifying signals of interest in the audio band. In real-world, audio signals are prone to outdoor noise which can be destructive for hearing aid. Eliminating interfering noise at high speed and low power consumption became a target for recent researches. Modern hearing compensation technologies use digital signal processing which requires minimum implementation costs to reduce power consumption, as well as avoiding delay in real time processing. In this paper, frequency controlled noise cancellation (FCNC) strategy for hearing aid and audio communication is developed with low complexity and least time delay. The contribution of the current work is made by offering a method that is capable of removing inherent distortion due filter-bank insertion and assigning adaptive filtering to a particular sub-band to remove external noise. The performance of the proposed FCNC was examined under frequency-limited noise, which corrupts particular parts of the audio spectrum. Results showed that the FCNC renders noise-immune audio signals with minimal number of computations and least delay. Mean square error (MSE) plots of the proposed FCNC method reached below -30 dB compared to -25 dB using conventional sub-band method and to -10 dB using standard full-band noise canceller. The proposed FCNC approach gave the lowest number of computations compared to other methods with a total of 346 computations per sample compared to 860 and 512 by conventional sub-band and full-band methods respectively. The time delay using FCNC is the least compared to the other methods.
Pengaruh Gaya Hidup Berbelanja Dan Perilaku Hedonik Terhadap Pembelian Impulsif (Studi) Pada Toko Belanja Online Shopee
Authors: Anggreani Debora Dian Maydiana , Suciarto A. Sentot 
Published: June 2020

This research aimed to test the effect of shopping lifestyle and hedonic behavior toward impulsive buying. Population researched here are students consuming shopee online shopping with sampel 100 taken by purposive sampling. It was obtained test result that respon toward shopping lifestyle was agree, average score 4.18. Average respon toward hedonic behavior was agree, 3.87. Average respon toward impulsive buying was agree, namely 3.92. Based on regression analysis, shopping lifestyle positively and significantly effected impulsive buying. Hedonic behavior also effected toward impulsive buying. The test result shopping lifestyle and hedonic behavior together significantly effected toward impulsive buying.
La Apoteosis de Hércules: un discurso humanista en la Sevilla del Renacimiento
Authors: Castillo Herrera Juan José 
Published: June 2020

El presente trabajo versa sobre la plasmación de las ideas humanistas del Renacimiento italiano de la 2ª mitad del s. XV en la pintura sevillana de los ss. XVI y XVII. El discurso se articula en base a una serie de reflexiones sobre cómo el pensamiento neoplatónico de los humanistas italianos quedó plasmado en las formas artísticas italianas, europeas y españolas y, en particular, en la obra de Francisco Pacheco, en concreto, sus pinturas en la “Casa de Pilatos” de Sevilla: La Apoteosis de Hércules. A través del estudio iconográfico y la interpretación de su discurso iconológico se establecen concordancias entre el pensamiento humanista y los principios del cristianismo con el fin de transmitir un mensaje moralizante.
Estética de la fotografía publicitaria
Authors: Sánchez Torreblanca Cristina María 
Published: June 2020

La cultura contemporánea es eminentemente visual, y en ella, la publicidad juega un importante papel. Buscando comunicar y persuadir al espectador, estas imágenes se adaptan a una serie de estereotipos sociales y culturales en los que resulta imprescindible el carácter estético. En este trabajo se analizarán los anuncios realizados en el siglo XXI a través del medio fotográfico, con el fin de establecer su identificación en relación a las categorías estéticas de lo bello, lo sublime, lo trágico, lo feo, lo cómico y lo kitsch.