bluuebunny/crossref_metadata_2025_split huggingface dataset:
A metal-electrode-free, fully integrated, soft triboelectric sensor array for self-powered tactile sensing
Authors: Wang Lingyun , Liu Yiming , Liu Qing , Zhu Yuyan , Wang Haoyu , Xie Zhaoqian , Yu Xinge , Zi Yunlong 
Published: August 2020

AbstractThe dramatic advances in flexible/wearable electronics have garnered great attention for touch sensors for practical applications in human health monitoring and human–machine interfaces. Self-powered triboelectric tactile sensors with high sensitivity, reduced crosstalk, and simple processing routes are highly desirable. Herein, we introduce a facile and low-cost fabrication approach for a metal-electrode free, fully integrated, flexible, and self-powered triboelectric tactile sensor array with 8-by-8 sensor units. Through the height difference between the sensor units and interconnect electrodes, the crosstalk derived from the electrodes has been successfully suppressed with no additional shielding layers. The tactile sensor array shows a remarkable sensitivity of 0.063 V kPa–1with a linear range from 5 to 50 kPa, which covers a broad range of testing objects. Furthermore, due to the advanced mechanical design, the flexible sensor array exhibits great capability of pressure sensing even under a curved state. The voltage responses from the pattern mapping by finger touching demonstrate the uniformity of the sensor array. Finally, real-time tactile sensing associated with light-emitting diode (LED) array lighting demonstrates the potential application of the sensor array in position tracking, self-powered touch screens, human–machine interfaces and many others.
100 pT/cm single-point MEMS magnetic gradiometer from a commercial accelerometer
Authors: Javor Josh , Stange Alexander , Pollock Corey , Fuhr Nicholas , Bishop David J. 
Published: August 2020

AbstractMagnetic sensing is present in our everyday interactions with consumer electronics and demonstrates the potential for the measurement of extremely weak biomagnetic fields, such as those of the heart and brain. In this work, we leverage the many benefits of microelectromechanical system (MEMS) devices to fabricate a small, low-power, and inexpensive sensor whose resolution is in the range of biomagnetic fields. At present, biomagnetic fields are measured only by expensive mechanisms such as optical pumping and superconducting quantum interference devices (SQUIDs), suggesting a large opportunity for MEMS technology in this work. The prototype fabrication is achieved by assembling micro-objects, including a permanent micromagnet, onto a postrelease commercial MEMS accelerometer using a pick-and-place technique. With this system, we demonstrate a room-temperature MEMS magnetic gradiometer. In air, the sensor’s response is linear, with a resolution of 1.1 nT cm−1, spans over 3 decades of dynamic range to 4.6 µT cm−1, and is capable of off-resonance measurements at low frequencies. In a 1 mTorr vacuum with 20 dB magnetic shielding, the sensor achieves a 100 pT cm−1 resolution at resonance. This resolution represents a 30-fold improvement compared with that of MEMS magnetometer technology and a 1000-fold improvement compared with that of MEMS gradiometer technology. The sensor is capable of a small spatial resolution with a magnetic sensing element of 0.25 mm along its sensitive axis, a >4-fold improvement compared with that of MEMS gradiometer technology. The calculated noise floor of this platform is 110 fT cm−1 Hz−1/2, and thus, these devices hold promise for both magnetocardiography (MCG) and magnetoencephalography (MEG) applications.
Triboelectric effect-modulated varifocal liquid lens
Authors: Fang Chunlong , Cao Yuanzhi , Jiang Dongdong , Tian Jiarui , Zhang Chi 
Published: August 2020

AbstractElectrically modulated varifocal liquid lenses, which are usually modulated by an external high voltage power source, have attracted much attention due to their bright application prospects in artificial optical systems. Here, a triboelectric nanogenerator (TENG)-based varifocal liquid lens (TVLL) has been demonstrated, in which the focal length can be directly modulated by external mechanical sliding. A dielectrophoretic force is generated by the TENG through the transfer of triboelectric charges in the asymmetric electrodes, which is used to continuously change the shape of the air–liquid interface between concave and convex without any complicated boost converter. Moreover, a triboelectric magnifying glass based on the accurate modulation effect of the TVLL on a light beam has been demonstrated. In this work, the TENG is used as a medium to modulate and accurately control the focal length of the liquid lens by an external mechanical stimulus, which may have great applications in micro-optical-electro-mechanical systems (MOEMS), human–machine interaction, artificial vision systems, etc.
How will new genetic technologies, such as gene editing, change reproductive decision-making? Views of high-risk couples
Authors: van Dijke Ivy , Lakeman Phillis , Mathijssen Inge B. , Goddijn Mariëtte , Cornel Martina C. , Henneman Lidewij 
Published: August 2020

AbstractCouples at increased risk of having offspring with a specific genetic disorder who want to avoid having an affected child have several reproductive options including prenatal diagnosis (PND) and preimplantation genetic testing (PGT). In the future, non-invasive prenatal diagnosis (NIPD), germline gene editing (GGE) and somatic gene editing (SGE) might become available. This study explores if, and how, availability of new genetic technologies, including NIPD, GGE, SGE, would change reproductive decision-making of high-risk couples. In 2018, semi-structured interviews were conducted with 25 genetically at-risk couples. Couples previously had received genetic counselling for PND and PGT, and in most cases opted for (one of) these techniques, at one Dutch Clinical Genetics Center between 2013 and 2017. Considerations participants mentioned regarding the hypothetical use of NIPD, GGE and SGE, seem similar to considerations regarding PND and PGT and are reflected in underlying concepts. These include safety and burden for mother and child, and moral considerations. Couples generally favoured NIPD over PND as this would be safe and enables earlier diagnosis. Increased opportunities of having a ‘healthy’ embryo and less embryo disposal were considerations in favour of GGE. Some regarded GGE as unsafe and feared slippery slope scenarios. Couples were least favourable towards SGE compared to choosing for a genetic reproductive technology, because of the perceived burden for the affected offspring. With the possibly growing number of technological options, understanding high risk couples’ perspectives can assist in navigating the reproductive decision-making process. Counsellors should be prepared to counsel on more and complex reproductive options.
Novel Approaches to Fine-Tune Therapeutic Targeting of Platelets in Atherosclerosis: A Critical Appraisal
Authors: Kessler Thorsten , Schunkert Heribert , von Hundelshausen Philipp 
Published: August 2020

AbstractThe pathogenesis of atherosclerotic vascular disease is driven by a multitude of risk factors intertwining metabolic and inflammatory pathways. Increasing knowledge about platelet biology sheds light on how platelets take part in these processes from early to later stages of plaque development. Recent insights from experimental studies and mouse models substantiate platelets as initiators and amplifiers in atherogenic leukocyte recruitment. These studies are complemented by results from genetics studies shedding light on novel molecular mechanisms which provide an interesting prospect as novel targets. For instance, experimental studies provide further details how platelet-decorated von Willebrand factor tethered to activated endothelial cells plays a role in atherogenic monocyte recruitment. Novel aspects of platelets as atherogenic inductors of neutrophil extracellular traps and particularities in signaling pathways such as cyclic guanosine monophosphate and the inhibitory adaptor molecule SHB23/LNK associating platelets with atherogenesis are shared. In summary, it was our intention to balance insights from recent experimental data that support a plausible role for platelets in atherogenesis against a paucity of clinical evidence needed to validate this concept in humans.
Are Self-Assessment and Peer Assessment of Added Value in Training Complex Pediatric Surgical Skills?
Authors: Joosten Maja , Bökkerink Guus M. J. , Verhoeven Bas H. , Sutcliffe Jonathan , de Blaauw Ivo , Botden Sanne M. B. I. 
Published: August 2020

Abstract
Introduction Self-assessment aids “reflection-before-practice,” which is expected to result in a better understanding of one's strengths and weaknesses and consequently a better overall performance. This is, however, rarely used in surgical training. This study aims to evaluate the correlation between self-, peer-, and expert assessment on surgical skills of pediatric surgical trainees.
Materials and Methods A competency assessment tool for the posterior sagittal anorectoplasty (CAT-PSARP) was previously developed and validated. During international hands-on pediatric colorectal workshops in 2019 and 2020, participants practiced the PSARP on an inanimate anorectal malformation model. They were assisted by a peer and assessed by two independent expert observers, using the CAT-PSARP. After the training session, both self- and peer assessment were completed, using the same CAT-PSARP.
Results A total of 79 participants were included. No correlation was found between the overall CAT-PSARP scores of the expert observers and the self-assessment (r = 0.179, p = 0.116), while a weak correlation was found between experts and peer assessment (r = 0.317, p = 0.006). When comparing the self-assessment scores with peer assessment, a moderate correlation was found for the overall performance score (r = 0.495, p < 0.001). Additionally, the participants who were first to perform the procedure scored significantly better than those who trained second on the overall performance (mean 27.2 vs. 24.4, p < 0.001).
Conclusion Participants, peers, and experts seemed to have a unique view on the performance during training because there was little correlation between outcomes of the trainees and the experts. Self-assessment may be useful for reflection during training; however, expert assessment seems to be essential for assessment of surgical skills.
Follicular Thyroid Carcinoma Presenting as a Humeral Mass: A Rare Case Presentation
Authors: Mendoza Marvin Jonne L. , Hernandez Aylmer Rex B. , San Juan Michael D. 
Published: August 2020

Follicular thyroid carcinoma is the second most common cancer of the thyroid, which usually presents as a solitary thyroid nodule. Diagnosis of follicular thyroid cancer involving the appendicular skeleton is very rare. In this paper, we report a case of a 65-year-old woman who previously underwent partial lobectomy of the left thyroid gland, and who consequently presented with a 2-year history of gradually enlarging left arm mass. Initial whole-body bone imaging revealed a large osteolytic lesion in the humerus. An MRI (magnetic resonance imaging) of the left arm showed a heterogeneously enhancing, encapsulated, soft tissue mass with humeral involvement, and the initial impression was osteosarcoma versus fibrosarcoma. Biopsy reading of the humeral mass was morphologically compatible with a well-differentiated metastatic thyroid carcinoma. She subsequently underwent right lobectomy where histopathology showed Hashimoto’s thyroiditis. A slide review was requested and the biopsy of the humeral mass revealed adenocarcinoma with follicular architecture, compatible with a metastatic thyroid carcinoma. Meanwhile, the findings on the right thyroid lobe revealed a multinodular colloid adenomatous goiter with hyperplastic features in a background of Hashimoto’s thyroiditis.
This report demonstrated a rare presentation of follicular thyroid carcinoma metastasizing to the humerus that can be confused with primary bone tumors, both clinically and radiologically. Early diagnosis and a high index of suspicion is foremost for immediate and appropriate management.
More than intent: A bundling model of MNE–SME interactions
Authors: Hennart Jean-François 
Published: August 2020

AbstractAs a counterpoint to Prashantham and Birkinshaw, I present an alternative model of MNE–SME cooperation where either type of firms can take the role of content provider or distributor. I argue that MNEs will interact with SMEs when there are differences in optimal scale between the content creation and distribution stages of the value chain, and it is not feasible or efficient for either party to vertically integrate between these two stages. I then build two 2 × 2 bundling models, one in which the SME provides content and the MNE distributes it, and another with the reverse configuration. In these 2 × 2s the axes are the transactional properties of the two complementary inputs, content and distribution, that MNEs and SMEs bundle to create value. I show that these models can explain the forms taken by MNE–SME cooperation and their dynamics.
Gesturing in the wild
Authors: Valenzuela Javier , Pagán Cánovas Cristóbal , Olza Inés , Alcaraz Carrión Daniel 
Published: August 2020

AbstractPsycholinguistic evidence shows that spatial domains are automatically activated when processing temporal expressions. Speakers conceptualize time as a straight line deployed along different axes (mostly sagittal, though also vertical). The use of the lateral axis, which cannot be lexicalized in any language, has nonetheless been attested in temporal tasks in laboratories using a variety of experiments. This leads to the question of what axes are actually at work when conceptualizating time in oral communication.The present study examines a great number of temporal expressions, taken from television shows, noting their associated co-speech gestures. Our results show that (1) speakers overwhelmingly use the lateral axis; (2) they are not performing simple space-to-time mappings, but are using instead a “timeline”, a material anchor which is a far more complex construct and that can explain some of the intricacies and contextual variations shown in the pattern of results.
Boundary-crossing events across languages
Authors: Alonso Alonso Rosa 
Published: August 2020

AbstractThis study analyses how speakers of two typologically distinct first languages (English (N = 12) and Spanish (N = 16)) and a group of 19 Spanish second language learners of English express boundary-crossing events, what type of verb they use, and how they segment these motion events. The stimuli used were 12 pictures of boundary-crossing events indicating motioninto, out ofandovera bounded space. In task 1 participants described each of the 12 scenes freely and in task 2 they were provided with a specific Manner verb between brackets. Significant differences were found in boundary-crossing and event segmentation in both L1 and L2. Participants also differed significantly in the type of verb used in the two tasks.
What’s in a villain’s name?
Authors: Uno Ryoko , Shinohara Kazuko , Hosokawa Yuta , Atsumi Naho , Kumagai Gakuji , Kawahara Shigeto 
Published: August 2020

Abstract
This paper reports two case studies of sound symbolism using the naturalistic name corpora of characters from Disney and Pokémon. Building upon previous studies of sound symbolism, we tested two hypotheses: (1) voiced obstruents, which are generally associated with negative images, are favored in villainous characters’ names, while (2) bilabial consonants, which are symbolically associated with cuteness, are disfavored in such names. The results show that these tendencies hold in our corpora, suggesting that a concept that is as complex as “villain” can be signaled via sound symbolism. Theoretical implications for cognitive linguistics based on our results are discussed.
Echoing-contrast combination in non-ironic constructions
Authors: Reda Ghsoon 
Published: August 2020

AbstractTheLexical Constructional Model(LCM) describes ironic constructions as containing echoes that invoke two contrasting situations: expected and real. The reconciliation of the contrast, which happens at the implicational level, gives rise to specific meaning effects in terms of speaker’s emotional reaction (seeRuiz de Mendoza & Galera Masegosa, 2014). The present study elaborates on these insights showing that echoing and contrast can cooperate in non-ironic constructions. In these cases, however, a full-fledged interpretation of the speaker’s reaction happens at the illocutionary level as bearing the value of an indirect invitation to the hearer to assess the truth value of the expected situation. Hence, the collaboration of echoing and contrast in non-ironic constructions may effect conceptual change/development. This is consistent with yet another observation made by the LCM; namely, that the cooperation of echoing and contrast operations in ironic constructions involves a concept-building operation (Ruiz de Mendoza, 2017).
Availability and accessibility of primary mental health services for adolescents: an overview of national recommendations and services in EU
Authors: Michaud Pierre-André , Visser Annemieke , Vervoort Johanna P M , Kocken Paul , Reijneveld Sijmen A , Jansen Danielle E M C 
Published: August 2020

Abstract

Background
Mental health problems in adolescence can profoundly jeopardize adolescent current and future health and functioning. We aimed to describe existing recommendations and services regarding the delivery of primary mental health care for adolescents in 31 European countries.

Methods
Data on the availability and accessibility of primary mental health services were collected, as part of the Horizon 2020-funded project Models of Child Health Appraised. One expert from each country answered a closed items questionnaire during years 2017–18.

Results
All 31 participating countries had some policy or recommendations regarding the availability and accessibility of primary mental health services for adolescents, but their focus and implementation varied largely between and within countries. Only half of the participating countries had recommendations on screening adolescents for mental health issues and burdens. Merely a quarter of the countries had ambulatory facilities targeting specifically adolescents throughout the whole country. Just over half had some kind of suicide prevention programs. Same-day access to primary care in case of -health emergencies was possible in 21 countries, but often not throughout the whole country. Nineteen countries had strategies securing accessible mental health care for vulnerable adolescents.

Conclusions
Overall, around half of European countries had strategies securing access to various primary mental health care for adolescents. They frequently did not guarantee care over the whole country and often tackled a limited number of situations. EU countries should widen the range of policies and recommendations governing the delivery of mental health care to adolescents and monitor their implementation.
Convergent Evolution and Structural Adaptation to the Deep Ocean in the Protein-Folding Chaperonin CCTα
Authors: Weber Alexandra A -T , Hugall Andrew F , O’Hara Timothy D 
Published: August 2020

AbstractThe deep ocean is the largest biome on Earth and yet it is among the least studied environments of our planet. Life at great depths requires several specific adaptations; however, their molecular mechanisms remain understudied. We examined patterns of positive selection in 416 genes from four brittle star (Ophiuroidea) families displaying replicated events of deep-sea colonization (288 individuals from 216 species). We found consistent signatures of molecular convergence in functions related to protein biogenesis, including protein folding and translation. Five genes were recurrently positively selected, including chaperonin-containing TCP-1 subunit α (CCTα), which is essential for protein folding. Molecular convergence was detected at the functional and gene levels but not at the amino-acid level. Pressure-adapted proteins are expected to display higher stability to counteract the effects of denaturation. We thus examined in silico local protein stability of CCTα across the ophiuroid tree of life (967 individuals from 725 species) in a phylogenetically corrected context and found that deep-sea-adapted proteins display higher stability within and next to the substrate-binding region, which was confirmed by in silico global protein stability analyses. This suggests that CCTα displays not only structural but also functional adaptations to deep-water conditions. The CCT complex is involved in the folding of ∼10% of newly synthesized proteins and has previously been categorized as a “cold-shock” protein in numerous eukaryotes. We thus propose that adaptation mechanisms to cold and deep-sea environments may be linked and highlight that efficient protein biogenesis, including protein folding and translation, is a key metabolic deep-sea adaptation.
Standardized Laboratory Methodology for the Evaluation of Foraging Strategies in Necrophilous Beetles: A Case Study of Necrophila (Calosilpha) brunnicollis (Coleoptera: Silphidae)
Authors: Jakubec Pavel , Kadlec Jakub , Šípek Petr 
Published: August 2020

Abstract
Precise data regarding feeding habits of necrobiont species are a key element of food web and evolutionary ecology. They can also be used to assess the utility and value of those species for forensic entomology, where obligatory necrophagous species in particular are considered good bioindicators of postmortem or preappearance interval. However, the feeding habits of many species are known only from anecdotal field observations, often reduced to vaguely defined categories—predatory, necrophagous, or omnivorous. To address this issue, we designed a simple, in vitro behavioral experiment allowing the quantification of food preferences. Next, we applied it on Necrophila (Calosilpha) brunnicollis (Kraatz, 1877), which is a common carrion beetle of East Asia with unresolved food preferences. The results suggest that this species is preferentially necrophagous, thus valuable for forensic research. Importantly, however, our experimental design allowed us to reveal that it also readily feeds on larvae of Diptera, although they compose a minor proportion of its diet. This methodology can be applied to other species, and it could provide evidence for future decision making in forensic research.