bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seasonal variability in copepod biomass in a cyclonic eddy in the Bay of La Paz, southern Gulf of California, Mexico
Authors: Rocha Díaz Franco Antonio , Monreal Gómez María Adela , Monter Erik Coria , de León David Alberto Salas , Durán Campos Elizabeth 
Published: March 2020

AbstractAs one of the main groups composing marine zooplankton, copepods play an important role due to the position they occupy in the trophic web. Study of their biomass and relationship with the physical conditions of the water column are essential in order to evaluate the trophic structure and functions of any aquatic ecosystem. As a contribution to this topic, we assessed the copepod biomass inside a cyclonic eddy system during two different seasons in the Bay of La Paz in the southern Gulf of California, a region characterized by high biological productivity. Two oceanographic expeditions took place in the winter of 2006 and summer of 2009 on which a conductivity-temperature-depth (CTD) probe was used to determine the physical structure of the water column and oblique zooplankton hauls collected zooplankton samples. Satellite data were used to visualize chlorophyll-a distribution patterns. The results showed the presence of a well-defined mesoscale cyclonic eddy in both seasons, with high chlorophyll-a (CHLA) values at the edges of the eddy. Maximum values for copepod biomass were observed in winter and their distribution corresponded well with the circulation pattern and the CHLA values, forming a belt shape following the periphery of the eddy. The results presented herein highlight the impact of the mesoscale eddy on the planktonic ecosystem through its influence on hydrographic conditions in the water column. Other factors, such as ecological interactions, population dynamics, and feeding habits may play a role as well. Feeding behavior in particular is affected by high CHLA concentrations observed around the eddy which represent a source of food for these organisms.
Potential geographic distribution of the Tiger MosquitoAedes albopictus(Skuse, 1894) (Diptera: Culicidae) in current and future conditions for Colombia
Authors: Echeverry-Cárdenas Emmanuel , López-Castañeda Carolina , Carvajal-Castro Juan D. , Aguirre-Obando Oscar Alexander 
Published: March 2020

ABSTRACTIn Colombia, little is known on the distribution of the Asian mosquitoAedes albopictus, main vector of dengue, chikungunya, and Zika in Asia and Oceania. Therefore, this work set out to estimate its current and future potential geographic distribution under the Representative Concentration Paths (RCP) 2.6 and 8.5 emission scenarios by 2050 and 2070, using ecological niche models. For this, predictions were made in MaxEnt, employing occurrences ofA. albopictusfrom their native area and South America and bioclimatic variables of these places. It was found that, since its invasion to Colombia,A. albopictusis present in 47% of the country, in peri-urban (20%), rural (23%), and urban (57%) areas between 0 and 1800 m, with Antioquia and Valle del Cauca being the departments with the most registries. The current estimation suggests thatA. albopictusis distributed in 96% of the territory up to 3000 m (p < 0.001). Additionally, by 2050 and 2070, below RCP 2.6, its distribution could diminish to nearly 90% including altitudes of 3100 m, while below RCP 8.5 it would be < 60% increasing its distribution up to 3200 m. These results suggest that, currently in Colombia,A. albopictusis found throughout the country and climate change could diminish eventually its area of distribution, but increase its altitudinal range. In Colombia, surveillance and vector control programs must focus their attention on this vector to avoid complications in the national public health setting.
Malaria in Southern Venezuela: The Hottest Hotspot in Latin America
Authors: Grillet ME , Moreno JE , Hernández JV , Vincenti-González MF , Noya O , Tami A , Paniz-Mondolfi A , Llewellyn M , Lowe R , Escalante AA , Conn JE 
Published: March 2020

AbstractMalaria cases in Latin America reached ~1 million in 2017 and 2018, with 53% and 51% reported from Venezuela, respectively. In this study, we characterized the spatiotemporal dynamics of malaria transmission between 2007-2017 in southern Venezuela, the main endemic area of the country. We found that disease transmission was focal and more prevalent in the southeast of southern Venezuela where two persistent hotspots of Plasmodium vivax (76%) and P. falciparum (18%) linked to deforestation for illegal gold mining accounted for ~60% of the country-wide number of cases. Incidence has increased nearly tenfold in the last decade, showing an explosive epidemic growth due to a significant lack of disease control. We suggest that a source-sink pattern of Plasmodium sp. dispersal account for the re-emergence and progression of malaria transmission in the last 4 years across the country due to the internal migration of infected people to and from the hotspots and other malaria-prone ecosystems. We observe a similar pattern explaining the spillover of cases across international borders affecting neighboring countries. This study provides baseline epidemiological data and guidance for malaria control to further assess the dynamics of cross-border malaria, the role of asymptomatic carriers, drug-resistant evolution, and innovative control efforts in the Latin America region.
Anomalous Diffusion Characterization by Fourier Transform FRAP with Patterned Illumination
Authors: Geiger A.C. , Smith C.J. , Takanti N. , Harmon D.M. , Carlsen M.S. , Simpson G.J. 
Published: March 2020

AbstractFourier transform fluorescence recovery after photobleaching (FT-FRAP) with patterned illumination is theorized and demonstrated for quantitatively evaluating normal and anomalous diffusion. Diffusion characterization is routinely performed to assess mobility in cell biology, pharmacology, and food science. Conventional FRAP is noninvasive, has low sample volume requirements, and can rapidly measure diffusion over distances of a few micrometers. However, conventional point-bleach measurements are complicated by signal-to-noise limitations, the need for precise knowledge of the bleach beam profile, potential for bias due to sample heterogeneity, and poor compatibility with multi-photon excitation due to local heating. In FT-FRAP with patterned illumination, the time-dependent fluorescence recovery signal is concentrated to puncta in the spatial Fourier domain through patterned bleaching, with substantial improvements in signal-to-noise, mathematical simplicity, representative sampling, and multiphoton compatibility. A custom nonlinear-optical beam-scanning microscope enabled patterned illumination for photobleaching through two-photon excitation. Measurements in the spatial Fourier domain removed dependence on the bleach profile, suppressing bias from imprecise knowledge of the point spread function. For normal diffusion, the fluorescence recovery produced a simple single-exponential decay in the spatial Fourier domain, in excellent agreement with theoretical predictions. Simultaneous measurement of diffusion at multiple length scales was enabled through analysis of multiple spatial harmonics of the bleaching pattern. Anomalous diffusion was characterized by FT-FRAP through a nonlinear fit to multiple spatial harmonics of the fluorescence recovery. Constraining the fit to describe diffusion over multiple length scales resulted in higher confidence in the recovered fitting parameters. Additionally, phase analysis in FT-FRAP was shown to inform on flow/sample translation.Statement of SignificanceFourier transform fluorescence recovery after photobleaching (FT-FRAP) with patterned illumination greatly improves the accuracy of diffusion assessments and simultaneously accesses information on both normal and anomalous diffusion in a single experiment.
A metabolic life table exemplified by sockeye salmon
Authors: Burger Joseph R. , Hou Chen , Hall Charles A.S , Brown James H. 
Published: March 2020

AbstractA metabolic life table (MLT) is a combination of energy budget and life table that quantifies metabolism and life history over an entire life cycle. It provides a conceptual framework for integrating data on physiology, demography and ecology that are usually the subject of discipline- and taxon-specific studies.Our MLT for sockeye salmon revives John Brett’s classic data on metabolism, growth, survival and reproduction to provide a synthetic analysis of metabolic performance and its life history consequences.The MLT quantifies the energy budget of an average female over her life cycle. The early stages in fresh water have low rates of growth and mortality. Then juveniles enter the ocean, feed voraciously, grow rapidly, and accumulate a store of biomass; More than 98% of the total lifetime assimilation and growth occurs in the ocean. Maturing adults stop feeding, return to fresh water, expend stored body energy to fuel migration and reproduction, and leave a clutch of eggs and a depleted carcass.The MLT also quantifies the energetic contribution of salmon to freshwater and marine ecosystems. Salmon are very efficient: of the food energy in their zooplankton prey, 47% is expended on respiration to fuel activity, 23% is allocated to growth and reproduction to produce biomass, and 30% is excreted in feces. Although 96% of lifetime biomass production occurs in the ocean, about 29% is transported into fresh water in the bodies of maturing adults, where their carcasses and gametes provide an important “marine subsidy” to the energy and nutrient budgets of freshwater and terrestrial ecosystems.The MLT highlights some features of the salmon metabolism – variation in rates of assimilation, respiration and production with body size and temperature – that are qualitatively similar to other ectotherms and predictions of metabolic theory. But because of the unusual physiology, life history, ecosystem impacts and socio-economic importance of wild-caught salmon, reanalyzing Brett’s data in the context of a MLT has additional broad applications for basic and applied ecology.
Membrane Association and Functional Mechanism of Synaptotagmin-1 in Triggering Vesicle Fusion
Authors: Prasad Ramesh , Zhou Huan-Xiang 
Published: March 2020

AbstractUpon Ca2+ influx, synaptic vesicles fuse with the presynaptic plasma membrane (PM) to release neurotransmitters. Membrane fusion is triggered by synaptotagmin-1, a transmembrane protein in the vesicle membrane (VM), but the mechanism is under debate. Synaptotagmin-1 contains a single transmembrane helix (TM) and two tandem C2-domains (C2A and C2B). The present study aimed to use molecular dynamics simulations to elucidate how Ca2+-bound synaptotagmin-1, by simultaneously associating with VM and PM, brings them together for fusion. While C2A stably associates with VM via two Ca2+-binding loops, C2B has a propensity to partially dissociate. Importantly, an acidic motif in the TM-C2A linker competes with VM for interacting with C2B, thereby flipping its orientation to face PM. Subsequently C2B can readily associate with PM via a polybasic cluster and a Ca2+-binding loop. These results delineate the functional process of fusion triggered by synaptotagmin-1.
GABAergic neurons and NaV1.1 channel hyperactivity: a novel neocortex-specific mechanism of Cortical Spreading Depression
Authors: Chever Oana , Zerimech Sarah , Scalmani Paolo , Lemaire Louisiane , Loucif Alexandre , Ayrault Marion , Krupa Martin , Desroches Mathieu , Duprat Fabrice , Cestèle Sandrine , Mantegazza Massimo 
Published: March 2020

AbstractCortical spreading depression (CSD) is a pathologic mechanism of migraine. We have identified a novel neocortex-specific mechanism of CSD initiation and a novel pathological role of GABAergic neurons. Mutations of the NaV1.1 sodium channel (theSCN1Agene), which is particularly important for GABAergic neurons’ excitability, cause Familial Hemiplegic Migraine type-3 (FHM3), a subtype of migraine with aura. They induce gain-of-function of NaV1.1 and hyperexcitability of GABAergic interneurons in culture. However, the mechanism linking these dysfunctions to CSD and FHM3 has not been elucidated. Here, we show that NaV1.1 gain-of-function, induced by the specific activator Hm1a, or mimicked by optogenetic-induced hyperactivity of cortical GABAergic neurons, is sufficient to ignite CSD by spiking-generated extracellular K+build-up. This mechanism is neocortex specific because, with these approaches, CSD was not generated in other brain areas. GABAergic and glutamatergic synaptic transmission is not required for optogenetic CSD initiation, but glutamatergic transmission is implicated in CSD propagation. Thus, our results reveal the key role of hyper-activation of Nav1.1 and GABAergic neurons in a novel mechanism of CSD initiation, which is relevant for FHM3 and possibly also for other types of migraine.
Archetypal images emerging in the therapy of Lithuanian cancer patients
Authors: Bulotiene Giedre 
Published: March 2020

AbstractThe goal of this paper is to show through clinical examples how archetypal images connected with nature emerged in Lithuanian cancer patients, to analyze how these images helped them to get in touch with their emotions and meaningful personal experiences, and to discuss how these archetypal images are related to the Lithuanian cultural unconscious, and may also assist the psychological treatment of cancer.The analyzed examples permit the preliminary conclusion that when ill with cancer, a person's psyche generates universal archetypal images that constitute an important part of the process of coping psychologically with the disease.
Difference – is it hated or desired? Reflections on the totalitarian state of mind
Authors: Czubinska Grazyna 
Published: March 2020

AbstractIn an age of polarized political views and growing nationalism it is vital that the psychoanalytic profession offers its contribution. The author makes a link between early infant development and social and political behaviour. Psychoanalytic, Jungian and Relational ideas are explored. Starting from Freud and his theory of ‘minor differences’, a dichotomy between closeness and separateness is investigated. The writer argues that difference is at the centre of human identity and human development and explores why we struggle to accept it. The totalitarian political system is described as one that eliminates difference. A case study is offered as an illustration of a patient’s struggle to move from a symbiotic, undifferentiated state towards object relating and individuation.
Displacement as trauma and trauma as displacement in the experience of refugees
Authors: Luci Monica 
Published: March 2020

AbstractThis paper investigates the relations between displacement, home, trauma and the self in the experience of refugees, which has become an issue of unexpected and far‐reaching proportions in recent times. It questions to what extent and under what conditions displacement in the world may be traumatic and how trauma may be considered the effect of an inner displacement. Refugees’ lives are marked by forced migration that is related to a certain suffering due to the changes in their family, relational, social and cultural lives. The paper explores the extent to which these changes can represent a break so significant as to be traumatic. It outlines the way in which traumatic experiences can produce an inner displacement and reorganization of one’s mental life that leads to a focus on traumatic complexes. Under the most severe traumatic conditions, this can be understood as a displacement of the central axis of Self, in which the ego complex yields its position to other complexes, with a deep change in the organization and functioning of self. The experience of refugees highlights the way in which we live in a matrix of conscious and unconscious links between inner and outer worlds that need deeper and simultaneous consideration to understand their implications and mutual resonances for the psyche. Clinical cases of refugees will illustrate some aspects of these interconnections.
The construct of the ‘mana personality’ in Jung’s works: a historic‐hermeneutic perspective. Part I
Authors: Sorge Giovanni V.R. 
Published: March 2020

AbstractAccording to Jung, the ‘mana personality’ represents an archetypal phase of the individuation process of remarkable interest in psychological, hermeneutic and theoretical terms. This figure is characterized by a high initiatic potential that fosters the approximation of the consciousness of the Self. At the same time, it entails a risk of psychic inflation or of ‘similarity to God’. In this article, divided in two parts, I deal with those aspects through a reconstruction of the development of this notion within Jung’s published works, adopting a primarily chronological and, secondarily, thematic approach moving from a textual analysis of relevant passages. In this first part, I consider some passages which deal mainly with the risks of the assimilation of the unconscious in ‘La structure de l’inconscient’ (1916) that preceded the successive proper treatment of the mana personality’s notion presented, and here examined, in ‘The relations between the ego and the unconscious’ (1928). Successively, I take into consideration some further issues related to it discussed by Jung in ‘The structure of the psyche’ (1928/1931), ‘Archaic man’ (1931), and ‘Nietzsche’s Zarathustra’.
Language, politics and dreams: the challenges of building resilience in refugees
Authors: Zarbafi Ali 
Published: March 2020

AbstractThis paper describes a case study of a 60‐year‐old Peruvian refugee in some detail, focusing on the importance of building emotional resilience in a patient in Spanish in order to create a space for learning the English language – the patient did not speak English after 20 years of living in Britain. The work was carried out with an interpreter and some of the literature on working with interpreters is referred to. The paper also briefly outlines the refugee journey in broad terms, which is a journey from the culturally known to the culturally unknown. The question of how well the literature on resilience, which sits firmly within a Western developmental perspective, can be applied to refugees, most of whom come from group and family‐based cultures dominated by ideas of honour and shame, is discussed. The paper also touches on the importance of the receiving country enabling or not, as the case may be, a transitional space for refugees who have lost their home and are seeking to find a safe haven in a strange culture.
The snake in the mandala: dialogical aspects of Jung’s ‘A study in the process of individuation’
Authors: Jones Raya 
Published: March 2020

AbstractJung’s study centres on the amplification of pictures painted by a woman patient and posits their sequence as evincing the initial stages of the individuation process. His text performs a dialogue with its audience whereby Jung persuades us of this truth, and also reveals Jung’s dialogue with his patient and with his own ideas. The present paper revisits the clinical material first with a focus on the interaction between Jung and his patient. The second part compares the 1940 and 1950 versions of Jung’s study with attention to tensions that traverse them, such as Jung’s attitude to the animus and his two voices as a practitioner and a theorist.
Curriculum mapping food science programs: An approach to quantification of professional competencies
Authors: Weston Emma , Benlloch‐Tinoco Maria , Mossop Liz , McCullough Fiona , Foster Tim 
Published: March 2020

AbstractIt is fundamental that students are able to identity where they have developed specific professional competencies during their study. This ensures students can not only articulate their competencies well in job applications and assessments but also draw on their experiences for use in the workplace. The aim of study was to ascertain if desirability of an element or competency as indicated by employers, was reflected in an equivalent level of program content, appropriately perceived by the student. A case study approach mapped elements of the previously developed Competencies for Food Graduate Careers framework against food sciences curricula at University of Nottingham. The mapping process facilitated evaluation of appropriate levels of inclusion of each element in degree programs, by recording types of content and experiences provided, in collaboration with teaching staff. Perspectives of the student experience were captured using an online survey. In addition, guidance from a prior industry survey provided context of the level of desirability for each element across the range of graduate roles in the United Kingdom. The results showed some areas of mismatch, where curricular content did not align with employer expectations or student perceptions. This has informed review of this curriculum, to best reflect “competency development” to meet the needs of the food industry. Recommendations were made to address gaps through enhancement of content, delivery, communication, or assessment. Additionally, the exercise has suggested a more informed development of curricula categorization and coding for future similar mapping activities.
Jack's Sports Bar
Authors: Kalesnikoff Douglas 
Published: March 2020

ABSTRACTThis two‐part case focuses on indicators or red flags of a possible fraud being committed by a majority shareholder against a minority shareholder. The student assumes the role of an accountant investigating the possible fraud. In Part 1 the student is provided with a whistleblower complaint and examines the draft financial statements that will be used for the purchase price of the sale of shares by the minority shareholder to the majority shareholder. In Part 2 the student is provided with further information on inventory controls and the accounting practices. Drawing on the student's knowledge of control systems and financial statement analysis, the student's task is to identify the possible fraudulent transactions and quantify their effect.
Activity‐Based Costing in a Challenging Business Environment: An Instructional Case
Authors: Alrishani Sameer 
Published: March 2020

ABSTRACTThis cross‐disciplinary case study uses the concept of the Production Sharing Agreement (PSA) in the upstream petroleum industry to demonstrate the application of activity‐based costing in a challenging international business environment. The case is designed and implemented to encourage students to critically address and solve legal, operational, and accounting challenges from a global perspective. This case is intended to be an appropriate hands‐on, experiential tool for undergraduate degree‐level managerial accounting classes. The learning objectives of this case include (i) to develop an understanding of the PSAs and identify their potential related challenges; (ii) to apply activity‐based costing using a multiple‐step approach in a unique, international, realistic, and challenging environment; and (iii) to identify the gaps between the current case activity‐based costing application and IFRS.