bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFEKTIVITAS INISIASI MENYUSU DI EFEKTIVITAS INISIASI MENYUSU DINI TERHADAP PERUBAHAN SUHU TUBUH PADA BAYI BARU LAHIR DI KLINIK SEHATI MEDAN
Authors: Sari Indah Dewi 
Published: April 2020

Bayi baru lahir 30 menit pertama dapat mengalami penurunan suhu tubuh 3-40C. Pada ruangan dengan suhu 20-250C suhu tubuh bayi turun sekitar 0,30C per menit. Kemampuan bayi yang belum sempurna dalam memproduksi panas sangat rentan untuk mengalami hipotermi. Inisiasi menyusu dini berpengaruh pada suhu tubuh bayi baru lahir, karena kehilangan panas pada bayi empat kali lebih besar dari pada orang dewasa. Inisiasi menyusu dini juga dapat menyelamatkan 22 persen dari bayi yang meninggal sebelum usia satu bulan. Tujuan penelitian ini adalah untuk mengetahui efektifitas inisiasi menyusu dini terhadap perubahan suhu tubuh pada bayi baru lahir di klinik Sehati Medan
Desain penelitian ini menggunakan quasi ekperimen dengan pendekatan prestest dan posttest. Metode pengambilan sampel dengan cara accidental sampling. Data dikumpulkan dengan cara observasi, dan dianalisis menunakan uji wilcoxon secara komputerisasi dengan tingkat kemaknaan P-Sign < 0,05.
Hasil penelitian menunjukkan bahwa hampir 90% bayi baru lahir sebelum dilakukan inisiasi menyusu dini mengalami penurunan suhu tubuh dan sesudah dilakukan inisiasi menyusu dini hanya 10% yang mengalami suhu tubuh rendah. Dari hasil pengujian statistik diperoleh hasil dengan Z = -4,243 dan p value = 0,000.
Kesimpulan pada penelitian ini adalah ada efektifitas pengaruh inisiasi menyusu dini terhadap perubahan suhu tubuh bayi baru lahir di klinik Sehati Medan 2019. Diharapkan pada bidan yang melakukan pertolongan persalinan agar memberikan tindakan inisiasi menyusu dini kepada setiap bayi baru lahir untuk mencegah terjadinya hipotermi.

Kata Kunci : Inisiasi Menyusu Dini, Perubahan Suhu Tubuh, Bayi Baru Lahir
Student perceptions of the care of children: impacts of pre-clerkship pediatric and primary care clinical teaching
Authors: Karras Beverley , Selvaraj Saumya , McConnell Athena , Andres Deirdre , Trinder Krista , McKague Meredith 
Published: April 2020

Background: Pediatric clinical skills teaching sessions provide an early opportunity for students to be exposed to the medical care of children. This report describes second and third year medical students’ perceptions of and attitudes towards working with children before and after the pediatric clinical skills teaching sessions, and the experiences of those students precepted by pediatricians only compared to those students working with a combination of pediatricians and family physicians.Method: A 13 question survey was voluntarily completed before and after teaching sessions. Written reflective assignments were qualitatively analyzed for key themes. Response rate averaged 68% with class sizes of 84 and 85 students.Results: Students’ perceptions of the care of children were generally very positive. Some differences were found based on gender, phase of study and prior clinical exposure to pediatric care. Pre and post responses were similar, regardless of preceptor specialty. Students with family physician preceptors identified the themes of prevention, health promotion and multidisciplinary care in their reflections. Conclusions: Students had already formed positive attitudes toward the medical care of children and intended to care for children in their future practice. Further research is needed into the effects of pre-clerkship experiences in the care of children on choice of medical specialty.
Observations of a Quasi-periodic Pulsation in the Coronal Loop and Microwave Flux during a Solar Preflare Phase
Authors: Li Dong , Li Ying , Lu Lei , Zhang Qingmin , Ning Zongjun , Anfinogentov Sergey 
Published: April 2020

Abstract
We report a quasi-periodic pulsation (QPP) event simultaneously detected from the spatial displacements of the coronal loop at both EUV images and microwave emission during the preflare phase of a C1.1 flare on 2016 March 23. Using the motion magnification technique, a low-amplitude transverse oscillation with the growing period is discovered in a diffuse coronal loop in Atmospheric Imaging Assembly (AIA) image sequences at wavelength of 171 Å, and the initial oscillation period is estimated to be ∼397 s with a slow growth rate of 0.045. At the same time, a QPP with growing periods from roughly 300 s to nearly 500 s is discovered in the microwave flux in the same active region. Based on the imaging observations measured at EUV wavelengths by the AIA and at microwave 17 GHz by Nobeyama Radioheliograph, the diffuse coronal loop and the microwave radiation source are found to be connected through a hot loop seen in AIA images at wavelength of 94 Å. The growing period of the QPP should be related to the modulation of LRC-circuit oscillating process in a current-carrying plasma loop. The existence of electric currents may imply the non-potentialities in the source region during the preflare phase.
Single-Trip Multizone Gravel-Packing Case History Improves Anticipated Production from the Berantai Field
Authors: Damasena E. , Law Chen S. , Sakamrin A.R. , Rashid S. , Kristanto T. , Rahyang Indra S. 
Published: April 2020

The Berantai Field is a marginal sand-prone formation located offshore in the Malaysian Peninsula, and its development was chosen for Malaysia's first and second Risk Service Contracts (RSCs) to provide gas production within two years of the Field Development Project (FDP)'s execution. This field was initially considered as marginal with only an estimated 44 mmstb of oil and 440 mmscf of gas.
A key performance requirement was to complete and produce the gas wells, sand free at the targeted production rate of 150 mmscfd. However, during development of the field, up to twenty multilayered, unconsolidated sand formations that had not been forecasted in the FDP were discovered, increasing the challenges for the completion strategy.
The dual-string single-trip multi zone (STMZ) system was selected for the completions, as this technology had been proven to provide cost-effective, single-trip gravel-pack applications that could reduce overall cost, since the gravel packing for multiple zones could be performed in a single trip. Although completing long intervals has unique challenges for fixed- interval spacing, and the initial campaign presented other challenges, all seven wells were successfully delivered. A total of thirty one zones were treated. One of the wells not only had six gravel-packed zones completed in one trip, but also had the world's longest concentric wash pipe used in any dual string STMZ completion.
This paper will show how proper completion planning and dual string STMZ technology enabled the operator to deliver the committed gas production, saved ~150K USD per gravel-packed zone, and reduced approximately 2.2 days in average rig time per well. The challenges addressed during this campaign, the methodology followed in the completion design, detailed completion and pumping strategy success factors, and the production results obtained from this marginal field development will be presented.
Detailed Phenotypic and Functional Characterization of a Rare, Antibody-Dependent SLAM-Associated Protein Expression Pattern
Authors: Khanolkar Aaruni , Wilks Jeffrey D , Liu Guorong , Caparelli Edward A , De Moura Michelle , Yap Kai Lee , Mustafa Asma , Kadri Sabah , Huang Wei , Zheng Xiaotian T 
Published: April 2020

Abstract
SLAM-associated protein (SAP) is an adaptor molecule that facilitates critical effector functions in immune cells, and its deficiency causes X-linked lymphoproliferative disease type 1 in which effector responses directed against EBV are severely compromised. The primary objective of this study was to phenotypically and functionally characterize a rare, CD8 T cell–restricted bimodal SAP expression pattern observed in healthy, human donors with the widely used 1C9-SAP mAb clone. We initially observed this pattern during the clinical validation of our flow cytometry–based assay to diagnose X-linked lymphoproliferative disease type 1 in our laboratory. For this validation study, we used multiparameter flow cytometry to identify cytosolic SAP expression in lymphocyte subsets, and CD8 T cells from the donors displaying the rare SAP expression pattern mentioned above were separately further evaluated by intracellular cytokine and CD107a staining to examine polyfunctionality following PMA/ionomycin and HLA class I allele–restricted EBV peptide epitope–induced T cell activation. Our data revealed that SAP 1C9-hi CD8 T cells clearly displayed higher polyfunctional responses versus SAP 1C9-lo CD8 T cells following PMA/ionomycin stimulation. Furthermore, polyfunctional EBV-specific CD8 T cell responses segregated with the SAP 1C9-hi CD8 T cells and not the SAP 1C9-lo CD8 T cells. Additionally, and rather intriguingly, short- and long-term T cell stimulation selectively diminished the signal for the 1C9-hi subset. Overall, our data suggest that although rare, this unique SAP expression pattern merits further evaluation as it has the potential to provide some insight into fundamental processes as they might relate to host–pathogen dynamics.
Association between self-rated health and physical performance in middle-aged and older women from Northeast Brazil
Authors: Fernandes Sabrina Gabrielle Gomes , Pirkle Catherine M. , Sentell Tetine , Costa José Vilton , Maciel Alvaro Campos Cavalcanti , da Câmara Saionara Maria Aires 
Published: April 2020

Background
Self-rated Health (SRH) is regarded as a simple and valid measure of a person’s health status, given its association to adverse health outcomes, including low physical performance in older populations. However, studies investigating these associations in low- and middle-income settings are scarce, especially for middle-aged populations. Understanding the validity of SRH in relation to objective health measures in low-income populations could assist in decision making about health policy and strategies, especially in under-resourced settings.

Objective
Assess the relationship between SRH and physical performance measures in middle-aged and older women in a low-income setting of Brazil.

Methods
This is a cross-sectional study of 571 middle-aged (40–59 years old) and older (60–80 years old) women living in Parnamirim and Santa Cruz in the Northeast region of Brazil. Participants reported their health status and were allocated to the “SRH good” or “SRH poor” groups. The physical performance evaluation included: handgrip strength, one-legged balance with eyes open and closed and chair stand test. The relationship between SRH and physical performance for middle-aged and older women was assessed by quantile regression (modeling medians) adjusted for potential confounders (age, socioeconomic variables, body mass index, menopause status, age at first birth, parity, chronic conditions and physical activity).

Results
Middle-aged women from the “SRH good” group presented better physical performance with 1.75 kgf stronger handgrip strength (95% CI [0.47–3.02]; p = 0.004), 1.31 s longer balance with eyes closed ([0.00–2.61]; p = 0.030), and they were 0.56 s faster in the chair stand test ([0.18–0.94]; p = 0.009) than those who reported “SRH poor”. No association was found for balance with eyes open. For older women, there was no evidence of associations between physical performance and SRH.

Conclusion
This study showed that SRH is significantly associated with objective measures of physical performance in a sample of low-income middle-aged women. SRH can be an important tool to indicate the need for further evaluation of physical performance among middle-aged women and can be particularly useful for low-income communities.
The whole body transcriptome of Coleophora obducta reveals important olfactory proteins
Authors: Wang Dongbai , Tao Jing , Lu Pengfei , Luo Youqing , Hu Ping 
Published: April 2020

Background
The tiny casebearer moth Coleophora obducta, an important defoliator of Larix spp., is a major threat to ecological security in north China. Studies have shown that C. obducta is strongly specific to host plants; it is unable complete its life cycle without Larix spp. The sex pheromones of C. obducta Z5-10:OH have been elucidated; and eight types of antennae sensilla, have been detected, indicating that an exploration of its olfactory proteins is necessary, due to the general lack of information on this topic.

Methods
We investigated the whole body transcriptome of C. obducta, performed a phylogenetic analysis of its olfactory proteins and produced expression profiles of three pheromone-binding proteins (CobdPBPs) by qRT–PCR.

Results
We identified 16 odorant binding proteins, 14 chemosensory proteins, three sensory neuron membrane proteins, six odorant degrading enzymes, five antennal esterases, 13 odorant receptors, seven ionotropic receptors and 10 gustatory receptors, including three PBPs and one odorant co-receptor. Additionally, three putative pheromone receptors, two bitter gustatory receptors and five functional ionotropic receptors were found by phylogenetic analysis. The expression profiles of three PBPs in males and females showed that all of them exhibited male-specific expression and two were expressed at significantly higher levels in males. These data provide a molecular foundation from which to explore the olfactory recognition process and may be useful in the development of a new integrated pest management strategy targeting olfactory recognition of C. obducta.
Effect of Foliar Application of Macro and Micronutrients on Quality of Kinnow Mandarin
Authors: . Reetika , Rana G. S. , . Komal , . Pooja , Rana M. K. 
Published: April 2020

Aims: To determine the suitable combination of fertilizers for obtaining high quality fruits from Kinnow orchard.
Study Design: The experiment was conducted in randomized block design with three replications per treatment on Kinnow mandarin.
Place and Duration of Study: The experiment was conducted on seven years old earmarked plants at Experimental Orchard and in Post-harvest Technology Laboratory of the Department of Horticulture, CCS Haryana Agricultural University, Hisar, Haryana, India during the year 2016-17.
Methodology: The treatments comprising of 11 combinations of Urea, K2SO4, ZnSO4, FeSO4 and boric acid which were laid out in randomized block design with three replications. Seven years old uniformly grown trees spaced at 6x6 m were selected for the present study and analyzed for yield and quality parameters such astotal soluble solids (%), acidity (%), ascorbic acid (mg/100 ml juice), juice content (%), TSS to acid ratio etc.
Results: In comparison to other fertilizers combinations, the maximum fruit yield per plant (97.83 kg/plant), juice content (49.47%), total soluble solids (9.80%), TSS to acid ratio (11.95) and ascorbic acid content (32.30mg/100ml) and minimum acidity (0.83%), rag (24.00%) and peel content (25.60%) and peel thickness (3.42 mm) were registered with foliar application of Urea 1.0% + K2SO4 1.0% + ZnSO4 0.5% + FeSO4 0.5% + H3BO3 0.2%, however, the foliar spray of Urea, K2SO4, ZnSO4, FeSO4 and boric acid had no effect on number of seeds per fruit in Kinnow mandarin. Thus it is clear from results that foliar nutrient application showed a stimulating influence on yield and quality parameters of Kinnow fruits.
Conclusion: From the research findings it can be concluded that the maximum potential of Kinnow mandarin plants in respect of fruit yield per plant, juice content, total soluble solids, TSS to acid ratio and ascorbic acid content was exploited to a maximum level and the acidity, rag and peel content and peel thickness to a minimum level with foliar application of Urea 1.0% + K2SO4 1.0% + ZnSO4 0.5% + FeSO4 0.5% + H3BO3 0.2%.
The Effect of Dash Diet on the Blood Pressure of the Male Hypertensive Office Employees between 33-55 Years of Age
Authors: Rai Chetna , Sengupta Rupali 
Published: April 2020

Aims: To determine the effect of the DASH Diet on the Blood Pressure of the male hypertensive office employees between 33-55 years of age.
Place and Duration of Study: The study was conducted at Abhitex International Company, Panipat, Haryana, India between November 2018 to January 2019.
Methodology: The Clinical blood pressure of the office employees of Abhitex International company, Panipat, between the age group of 35 to 55 years was recorded, following the international guidelines given by American Heart Association(AHA) and American College of Cardiology. Purposive sampling was done and the employees who had clinical blood pressure above 120/80 mm Hg were considered as the samples for the study. The dietary pattern of the samples was evaluated by checking the adherence to the DASH diet which was done through a questionnaire and 3 days 24-hour diet recall. Dietary adherence was assessed using a scoring scheme adopted by Folsom and colleagues. Samples were made aware of the DASH Diet and post one month the adherence to DASH Diet was again checked and the change in the clinical blood pressure was observed.
Results: There were 50 study participants. The mean age of the participants was 41.5 years. The average Systolic blood pressure of the 50 participants in the pre-test was 149.3 mm of Hg and average diastolic blood pressure was 89.58 mm of Hg. Pre Nutrition Education Program, the total mean DASH adherence score was 4.3 out of 10 but post NEP and after following DASH Diet, the adherence score for the DASH Diet improved and resulted in 6.7 which indicated that the samples adhered more to the DASH Diet post NEP. There were reductions in systolic (149.30±18.98 mmHg to 146.12±14.85 mmHg) and diastolic (89.58±8.76 mmHg to 86.28±4.76 mmHg) blood pressures when the subjects adhered towards the DASH Diet. A significant difference at p=0.05(p=0.039*) in the pre and post-systolic blood pressure was observed in the study. A similar trend was also noticed in the pre and post-diastolic blood pressure which showed a highly significant difference at p=0.05(p=0.002**).
Conclusion: It was concluded from the study that the improvement in the DASH Diet adherence score was associated with a reduction in the Clinical blood pressure. There was a reduction in systolic (149.30±18.98 mmHg to 146.12±14.85 mmHg) and diastolic (89.58±8.76 mmHg to 86.28±4.76 mmHg) blood pressures with an improvement of DASH Adherence Score (4.3±1.27 to 6.7±1.19).
Revisiting Puerperal Sepsis in Obsteric Referal Centres in Port Harcourt, Southern Nigeria
Authors: Okwudili Oranu Emmanuel , Oluwaseun Owolabi Ayodeji , Esther I. Nonye-Enyindah 
Published: April 2020

Background: As the frontier of knowledge expands, surgical skills improve; and with the advent of increasingly potent antibiotics, it is expected that puerperal sepsis and its complications as captured in the literature of studies will be on the down turn. With this in mind, we decided to find out what is current as par risk factors and complications of puerperal sepsis in these obstetric referral centres in Port Harcourt.
Objective: To determine the risk factors and complications of puerperal sepsis at the University of Port Harcourt Teaching Hospital(UPTH), Port Harcourt and the River State University Teaching Hospital (RSUTH), Port Harcourt, Nigeria.
Methods: The case notes of these patients were retrieved from the medical records departments and relevant data extracted using a well-structured proforma. Data collected included the demographic characteristics, booking status, background immune suppression (HIV/AIDS or DM), labour characteristics, place and mode of delivery, fetal outcome, length of hospital stay. Morbidities like septicaemia, pelvic abscess, disseminated intravascular coagulopathy among others; and the presence of mortality was also noted. The data was analyzed using SPSS version 23.0. Statistical analysis of data was done by Chi-square test. A p-value less than 0.05 was considered significant. The result is presented in tables of frequencies and percentages.
Results: The prevalence of puerperal sepsis was 1.7%. Risk factors were low parity, unbooked status (84.35%) and wound infection (29.9%), among other intrauterine foetal death (22.8%), obstructed labour (14.2%) and perineal tear (11.0%). The main complications of puerperal sepsis noticed were prolonged hospital stay (58.3%) and septicaemia (13.4%); pelvic abscess (10.2%) and intestinal obstruction (4.7%) while (1)3.1% ended in mortality.
Conclusion: Complications of puerperal sepsis were still high in these centres. Worrisomely, a huge number of these patients were unbooked.
Geological and Geoelectrical Investigation of a Proposed Dam Site Using Vertical Electrical Sounding at Osuworowo Stream, Utughughu Arochukwu, South Eastern Nigeria
Authors: Ezebunanwa A. C. , Nwugha V. N. , Emeghara K. C. , Ibe G. C. 
Published: April 2020

Geophysical studies was carried out at a proposed dam site across Osuworowo stream in Arochukwu, south eastern Nigeria to investigate the depth to bedrock, possible geologic structures and foundation conditions of the dam axis. The study area is located between latitudes 5°23.58”N and 5°23.707”N and longitude 7°53.93”E and 7°53.97”E. Its elevation ranges from 90 ft to 149 ft. Six Vertical Electrical Soundings (VES) were carried out along the stream course using ABEM SAS 1000 TERRAMETER and this was done using Schlumberger configuration with maximum half current electrode separation of 55m able to reveal deep seated structures. The ip2win software was used to model the VES data to give resistivities which vary between 258 Ωm and 39000 Ωm with three and four geoelectric layer combinations of sand, sandstone, sandyshale, shalysand and ale units. The high resistivities of the geoelectric layers sand thickness and dip showing high gradient in elevation differences are indications that the site is suitable for the dam construction. The geological result shows the presence of faults this is confirmed by change in strike and dip.
Advances in Activity‐Based Sensing Probes for Isoform‐Selective Imaging of Enzymatic Activity
Authors: Gardner Sarah H. , Reinhardt Christopher J. , Chan Jefferson 
Published: April 2020

AbstractUntil recently, there were no generalizable methods for assessing the effects of post‐translational regulation on enzymatic activity. Activity‐based sensing (ABS) has emerged as a powerful approach for monitoring small‐molecule and enzyme activities within living systems. Initial examples of ABS were applied for measuring general enzymatic activity; however, a recent focus has been placed on increasing the selectivity to monitor a single enzyme or isoform. The highest degree of selectivity is required for differentiating between isoforms, where the targets display significant structural similarities as a result of a gene duplication or alternative splicing. This Minireview highlights key examples of small‐molecule isoform‐selective probes with a focus on the relevance of isoform differentiation, design strategies to achieve selectivity, and applications in basic biology or in the clinic.