bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Hypothermia by JZL-184 on Muscle Strength and Sensory-Motor Dysfunction in Permanent Middle Cerebral Artery Ischemia Model in Male Mice
Authors: Rahmani Mohammad Reza , Allahtavakoli Mohammad 
Published: July 2020

Introduction: Currently, there is no effective and comprehensive treatment for ischemic stroke. There is strong clinical evidence for the benefits of hypothermia in neuroprotection. Therefore, the present study aimed to determine the effect of mild non-invasive hypothermia by JZL-184 on behavioral improvement in stroke rats.
Methods: This study was performed on 5 groups of male mice weighing 25-30 g. The groups were as follows: 1- Healthy group 2- Control group (Stroke) 3- Stroke + DMSO solvent 4- Stroke + Aspirin (40mg /kg) 5- Stroke + JZL-184 (16mg / kg) (n = 8 per group). The drugs were injected intraperitoneally immediately after the stroke. At the times before (time zero) and at 5, 24 and 48 h after stroke induction, body temperature, behavioral testing, including muscle strength and sensory-motor dysfunction were measured. Data were analyzed by SPSS version 18 software and Two-way ANOVA test (P ≤ 0.05).
Results: JZL-184 decreased body temperature at 5, 24 and 48 hours compared to intact and control groups (p <0.001). Injection JZL-184 and Aspirin improved muscle strength and sensory-motor function (p <0.001) compared to the control group. Aspirin also improved behavioral tests compared to the control group (p <0.01), but did not show any effect on the body temperature compared to the intact group at time 48. Only in JZL-184 group, the behavioral tests score was similar to the intact group at the 48 h after stroke.
Conclusion: JZL-184 may have been able to improve neuronal function by hypothermia induced by the agonist effects of cannabinoid receptor 1 (CB1), thereby improving muscle strength and sensory-motor function after cerebral ischemia.
Mortalidad perinatal
Authors: Páez Vargas Roberto A. , Acero Rodríguez Uriel , Uribe Correa Hermann 
Published: July 2020

La mortalidad perinatal es uno de los más eficientes indicadores del buen o mal funcionamiento de un Servicio de Maternidad; el análisis de sus cifras estadísticas a través de un juicio critico, revela generalmente la eficacia o errores en la atención materno-infantil de las pacientes atendidas en él; la razón por la cual se realiza el presente trabajo estadístico, que comprende un lapso de 10 años a partir de 1963, fecha de iniciación del Departamento de Obstetricia y Ginecología del Hospital Militar Central.
Students’ willingness to participate in speaking activities through the use of scripted role-plays
Authors: Lara Castro Jonathan Antonio , Díaz Larenas Claudio 
Published: July 2020

The following study is a result of an action research carried out in an English as a foreign language class in a subsidized Chilean school, where 77 % of its population is at social risk. 38 of the participants are seventh grade students. The study addresses students’ willingness to participate in speaking activities in English class before and after the implementation of a drama based pedagogy strategy known as scripted role-play.
The students showed great commitment to scripted role-play as a way to learn English. Participants had the chance to work collaboratively with their peers in a safe and engaging environment, improving their social skills as they performed different roles. The study concludes that students are willing to participate in speaking activities after the use of scripted role-plays. This result is also coherent with the students’ perceptions of the intervention.
ANALISIS FAKTOR YANG MEMPENGARUHI KEMAMPUAN ADAPTASI FAMILY CAREGIVER DALAM MERAWAT KELUARGA DENGAN KANKER STADIUM AKHIR DI POLI ONKOLOGI RSUD DR. SOETOMO SURABAYA
Authors: Purwaningsih Purwaningsih , Ulfiana Elida , Isrichawati Trias 
Published: July 2020

Introduction: Caring for family members with cancer takes a long time. Various problems that arise during treatment will have an impact on the physical condition and psychological care giver so that this will have an impact on family adaptation. The purpose of this study was to analyze the factors that influence the adaptation ability of family caregivers who care for families with terminal condition cancer in the Oncology Poly RSUD Dr. Soetomo Surabaya. Methods: A cross-sectional study design. The population in this study are families who care for family members with terminal condition cancer in the Oncology Polyclinic Dr. Soetomo as many as 138 respondents were obtained by purposive sampling. The independent variables are attitude, trust, family support, coping mechanisms, and role functions while the dependent variable is the adaptability of family caregiver who care for families with terminal condition cancer. The research instrument used questionnaire attitudes, beliefs, family support, coping mechanisms, role functions and adaptability. Data analysis using Spearman Rho with significance level p ≤ 0.05. Results: Attitudes, family support, coping mechanisms, role functions are related to family caregiver's adaptability, while trust is not related to family caregiver's adaptability. Conclusion: Adaptability is needed for family caregivers in caring for families with terminal condition cancer. Future researchers are expected to intervene further to improve family support and adaptive coping mechanisms to help overcome problems that arise during the treatment of patients with cancer. Keywords: Attitude, Trust, Family Support, Coping Mechanisms, Role Function, Terminal Condition Cancer
Marital Adjustment and Prenatal Breastfeeding Efficacy of First Time Mothers in A Low-Income Community in The Philippines
Authors: Gonzales Artemio Jr Morado 
Published: July 2020

Introduction: All women should be offered support to breastfeed their babies to increase the duration and exclusivity of breastfeeding. This study aims to assess the level of marital satisfaction and its influence to prenatal breastfeeding self-efficacy in first time mothers during late pregnancy.Methods: A descriptive correlational was conducted among 128 simple randomized prim gravid women who agreed to participate and had prenatal care check-up in the health center at the time of data gathering. The instruments used were 15-item Marital Adjustment Test (MAT) to measure marital adjustment and 14-item Breastfeeding Self efficacy Scale-Short Form (BSES-SF) as a measure of breastfeeding self-efficacy. Pearson’s correlation coefficient was utilized to test the relationships between the sample’s marital adjustment scores to correlate with BFSE of the respondents. Fisher’s t test was utilized to determine the significance of correlations. A p-value of equal to or less than .05 was considered statistically significant.Results: The study revealed that the sampled mothers have a high level of marital adjustment score (112.05± 21.83). Prenatal mothers responded in the study were highly confident and have high self-efficacy in breastfeeding first child currently bearing (4.55±.51). Lastly, it was found that there is no significant correlation between marital adjustment and prenatal breastfeeding self-efficacy (β=-.052, p-value=.280).Conclusion: It was found that there is a high level of marital adjustment and breastfeeding self-efficacy among sampled mothers. However, there is no significant correlation between marital adjustment and prenatal breastfeeding self-efficacy. The study suggests incorporating co-parenting intervention involving father’s involvement and assistance with breastfeeding when creating interventions in breastfeeding.
THE INFLUENCE OF BINAHONG LEAVES (ANREDERA CORDIFOLIA) ON HEALING OF FLOUR ALBUSON FEMALE STUDENTSOF CLASS XI SMAN 1 PACIRAN LAMONGAN DISTRICT
Authors: , Iswatun , Pangestu Anestasia , Nasir Abdul , Lailiyah Nazilatul , Aris Arifal 
Published: July 2020

Introduction: One problem of adolescents at the age of 11-20 years who have not entered adulthood is fluor albus. In the initial survey, more than half of the students (70%) had vaginal discharge problems. This study aimed to determine the effect of binahong leaves decoction (AnrederaCordifolia) on healing Flour Albuson female Student of class XI SMAN 1 Paciran, Lamongan District. Methods: The design used pre-experimental method with one grouppre test and post test. The population was all female students who had fluor albus of 34 children and sample of 25 children with consecutive sampling techniques that the inclusion creteria. The data were analyzedusing Wilcoxon Sign Rank Test, with significance level of p <0.05 using SPSS V program 22.0. Results: The results of statistical tests showed that the values of Z: -4.613b and p = 0.000 where p <0.05, H1 was accepted, meaning that there was an effect of binahong leaves decoction (AnrederaCordifolia) on healing Flour Albus. This study indicated that binahong leaf decoction herbs can reduce and even healing fluor albus with good personal hygiene behavior.
A Rare Case of Patella Fracture in Osteopetrosis
Authors: Khor Yuet Peng , Chee Yuhan 
Published: July 2020

Case:Fractures in patients with osteopetrosis pose unique technical challenges to the orthopaedic surgeon. We present a case of a 43-year-old man with osteopetrosis who underwent tension band wiring of a patella fracture. The intraoperative appearance of osteopetrotic bone, technical difficulties in passing wires through dense bone, and how this was overcome are presented.Conclusions:A simple transverse fracture of the patella in a patient with osteopetrosis can be fixed successfully using a standard tension band construct.
Retention of Monoblock Femoral Components Using a Dual Mobility Bearing
Authors: Kiran Manish , Peter Viju 
Published: July 2020

Case:
We present the results of 3 cases followed up for a minimum period of 4.5 years of revision total hip arthroplasty using a metal acetabular shell with retention of a well-fixed monoblock femoral component by inserting a dual mobility polyethylene bearing onto the femoral head in situ.

Conclusion:
This is the first case series to use this technique to address acetabular osteolysis and avoid removing a well-fixed monoblock femoral component at the time of revision surgery.
Hemiarthroplasty for Femoral Neck Fractures in the Elderly
Authors: DeRogatis Michael J. , Piatek Allison Z. , Jacob Roshan , Kelly Sean C. , Issack Paul S. 
Published: July 2020

» The incidence of displaced femoral neck fractures among elderly patients is increasing as the population ages.» Historically, the preferred treatment for displaced femoral neck fractures in elderly patients has been hemiarthroplasty with use of cemented fixation of the implant. However, there is evidence that this technique may be associated with fat embolization and subsequent cardiopulmonary arrest in the early postoperative period. Cementing techniques are also associated with increased operative time when compared with cementless techniques.» There is increasing evidence that, among elderly patients, the use of uncemented hemiarthroplasty has equivalent functional outcomes and overall mortality rates when compared with the use of hemiarthroplasty with cemented fixation. The main complication associated with uncemented hemiarthroplasty is intraoperative periprosthetic fracture.
Pengaruh Perlakuan pH dan Suhu Terhadap Sifat Fisikokimia Mocaf (Modified Cassava Flour)
Authors: Diniyah Nurud , Ganesha Pradiska Gita Vindy , Subagio Achmad 
Published: July 2020

<p>Peningkatan sifat fungsional pati dapat dilakukan dengan mengubah struktur pati menjadi lebih banyak pada bagian amorf dengan cara perlakuan fermentasi pada umbi singkong terlebih dahulu sehingga dihasilkan Mocaf. Tujuan penelitian ini adalah untuk mengetahui perubahan karakteristik pati Mocaf dengan perlakuan panas dan pengaturan tingkat keasaman (pH) agar dapat digunaan dalam aplikasi yang lebih luas. Perlakuan dalam penelitian ini meliputi variasi suhu pemanasan (60, 70, 80, 90, dan 120 °C) dan pH (3, 4, 5, 6, dan 7) dan diulang sebanyak 3 kali dengan parameter pengukuran meliputi daya kembang, kelarutan, kekeruhan, viskositas pasta, bentuk granula pati, dan sineresis. Hasil penelitian ini menunjukkan bahwa suhu pemanasan mempengaruhi nilai daya kembang, kelarutan, viskositas, bentuk granula pati, dan sineresis Mocaf, tetapi menyebabkan penurunan tingkat kekeruhan. Sedangkan penambahan asam dapat mempengaruhi viskositas dan granula pati Mocaf.</p><p> </p><p><strong>Effect of pH and Temperature Treatment on Physicochemical Properties of Mocaf (Modiffied Cassava Flour) </strong></p><p>The changes in the starch’s structure to amorphous can increase the functional characteristics of starch using the fermentation process of cassava to be known as Mocaf. The aim of this study was to determine the physicochemical properties of Mocaf’s starch due to temperature and pH processing. Treatment in this research including various of temperature (60, 70, 80, 90, and 120 °C) dan pH (3, 4, 5, 6, dan 7) in three replications with analysis of swelling power, solubility, viscosity, starch granule, and syneresis. The results of this study indicate that the heating temperature affects the value of swelling power, solubility, viscosity, starch granule, and syneresis of Mocaf, but it causes a decrease of Mocaf’s turbidity. The addition of acid may affect the viscosity and granules of Mocaf’s starch.</p>
Comparison of refractive outcomes after photorefractive keratectomy with different optical zones using Mel 90 excimer laser
Authors: Shin Dae Hwan , Lee Yong Woo , Song Ji Eun , Choi Chul Young 
Published: July 2020

Abstract
Background: A larger optical zone for photorefractive keratectomy may improve optical quality and stability. However, there is need for limiting ablation diameter in that a larger ablation diameter requires greater ablation depth, and minimizing ablation depth may reduce adverse effects on postoperative wound healing, haze and keratoectasia. In this study, we compared the changes in clinical outcomes and the degree of regression between a 6.0 mm optical zone and 6.5 mm optical zone following PRK. Methods: The records of 95 eyes that had undergone PRK with a 6.0 OZ ( n = 40) and a 6.5 OZ ( n = 55) were retrospectively reviewed. We compared data including the spherical equivalent of manifest refraction (SE of MR), simulated K (Sim K), thinnest corneal thickness, change in thinnest corneal thickness (the initial value divided by corrected diopter [ΔTCT/CD]), Q value, corneal higher order aberrations (HOAs) and spherical aberration (SA) pre-operation, at 3 and 6 months postoperative and at the last follow-up visit (Mean; 20.71 ± 10.52, 17.47 ± 6.57 months in the 6.0 and 6.5 OZ group, respectively). Results: There were no significant differences in the SE of MR, Sim K and UDVA between the 6.0 OZ group and the 6.5 OZ group over 1 year of follow-up after PRK, and the 6.0 OZ group required less ΔTCT/CD than the 6.5 OZ group. The 6.5 OZ group showed better results in terms of post-operative HOAs of RMS, SA and Q value. When comparing that pattern of change in Sim K, there was no significant difference between the 6.0 OZ group and the 6.5 OZ group. Conclusions: The clinical refractive outcomes and regression after PRK using Mel 90 excimer laser with a 6.0 OZ were comparable to those with a 6.5 OZ.
Shared decision-making in advance care planning for persons with dementia in nursing homes: a cross-sectional study.
Authors: Goossens Bart , Sevenants Aline , Declercq Anja , Audenhove Chantal Van 
Published: July 2020

Abstract

Background: Shared decision-making provides an approach to discuss advance care planning in a participative and informed manner, embodying the principles of person-centered care. A number of guided approaches to achieve shared decision-making already exist, such as the three-talk model. However, it is uncertain whether daily practice methods in nursing home wards for persons with dementia comply with the underpinnings of this model. It is also uncertain whether professionals consider shared decision-making to be important in this context, and whether they perceive themselves sufficiently competent to practice this approach frequently. Methods: The study has a cross-sectional design, with 65 wards (46 Belgian nursing homes) participating in the study. We compared nursing home professionals’ and residents’ perspectives on the level of shared decision-making during advance care planning conversations with ratings from external raters. Residents and professionals rated the level of shared decision-making by means of a questionnaire, which included the topic of the conversation. External raters assessed audio recordings of the conversations. Professionals filled in an additional self-report questionnaire on the importance of shared decision-making, their competence in practicing the approach, and with what frequency.Results: At ward level, professionals and residents rated the average achieved level of shared decision-making 71.53/100 (σ=16.09) and 81.11/100 (σ=19.18) respectively. Meanwhile, raters gave average scores of 26.97/100 (σ=10.45). Only 23.8% of residents referred to advance care planning as the topic of the conversation. Professionals considered shared decision-making to be important (x̄=4.48/5, σ=0.26). This result contrasted significantly with the frequency (x̄=3.48/5, σ=0.51) and competence (x̄=3.76/5, σ=0.27) with which these skills were practiced (P<0.001).Conclusions: Residents with dementia are grateful when involved in discussing their care, but find it difficult to report what is discussed during these conversations. Receiving more information about advance care planning could provide them with the knowledge needed to prepare for such a conversation. External raters observe a discrepancy between the three-talk model and daily practice methods. Training programs should focus on providing professionals with better knowledge of and skills for shared decision-making. They should also promote team-based collaboration to increase the level of person-centered care in nursing home wards for persons with dementia.
Nomogram Model for Predicting Cause-Specific Mortality in Patients with Stage I Small-Cell Lung Cancer: A Competing Risk Analysis
Authors: Li Jianjie , Zheng Qiwen , Zhao Xinghui , Zhao Jun , An Tongtong , Wu Meina , Wang Yuyan , Zhuo Minglei , Zhong Jia , Yang Xue , Jia Bo , Chen Hanxiao , Dong Zhi , Wang Jingjing , Zhai Xiaoyu , Chi Yujia , wang ziping 
Published: July 2020

Abstract
Background: The five-year cumulative incidence rate in patients diagnosed with stage I small-cell lung cancer(SCLC) who were instructed to undergo surgery was from 40% to 60%.The death competition influence the accuracy of the classical survival analyses.The aim of the study is to investigate the mortality of stage I small-cell lung cancer (SCLC) patients in the presence of competing risks according to a proportional hazards model, and to establish a competing risk nomogram to predict probabilities of both cause-specific death and death resulting from other causes.Methods : The study subjects were patients diagnosed with stage I SCLC according to ICD-O-3. First, the cumulative incidence functions (CIFs) of cause-specific death, as well as of death resulting from other causes, were calculated. Then, a proportional hazards model for the sub-distribution of competing risks and a monogram were constructed to evaluate the probability of mortality in stage I SCLC patients.Results: 1811 patients were included in this study. The five-year probabilities of death due to specific causes and other causes were 61.5% and 13.6%, respectively. Tumor size, extent of tumor, surgery, and radiotherapy were identified as the predictors of death resulting from specific causes in stage I SCLC. The results showed that surgery could effectively reduce the cancer-specific death, and the one-year cumulative incidence dropped from 34.5% to 11.2%. Like surgery, chemotherapy and radiotherapy improved the one-year survival rate.Conclusions: We constructed a predictive model for stage I SCLC using the data from the SEER database. The proportional sub-distribution models of competing risks revealed the predictors of death resulting from both specific causes and other causes. The competing risk nomogram that we built to predict the prognosis showed good reliability and could provide beneficial and individualized predictive information for stage I SCLC patients.
The Clinical Learning Environment, Supervision and Nurse Teacher Scale (CLES+T): psychometric properties measured in the context of postgraduate nursing education
Authors: Ozga Dorota , Gutysz-Wojnicka Aleksandra , Lewandowski Bogumił , Dobrowolska Beata 
Published: July 2020

Abstract

Background. The Clinical Learning Environment, Supervision and Nurse Teacher Scalehttps://www.youtube.com/watch?v=4HFG5RyQPqY(CLES+T) instrument is internationally used for the evaluation of clinical learning environment in undergraduate nursing education. However, no evidence is available on the possible applications of this instrument in the context of postgraduate nursing education.Purpose. To examine the basic psychometric properties of CLES+T in the context of clinical postgraduate nursing education in Poland.Methods. Study among a sample of 417 nurses participating in the clinical postgraduate training in Poland.Results. Cronbach’s alpha for the total scale was 0.97. A five-factor structure was confirmed in accordance with the assumptions adopted by the authors of the original version of the scale. Cronbach’s alpha coefficient for the Polish version of the CLES+T subscales ranged from 0.83 (Nursing care on the ward) to 0.95 (The content of supervisory relationship). The mean results for individual subscales ranged from 4.52±0.63 fornursing care on the wardto4.73±0.45 forrole of the nurse teacher.Conclusions. Having shown satisfactory psychometric properties, CLES+T can be considered a useful instrument to assess those elements of clinical learning environment which are important for the assurance of education quality at the postgraduate level.