bluuebunny/crossref_metadata_2025_split huggingface dataset:
Common Variable Immunodeficiency Presenting with Recurrent Ascending Cholangitis Treated with Oral Immunoglobulins
Authors: Rowane Marija , Patel Jaimin , Abraham Tina , Schend Jason , Hostoffer Robert 
Published: January 2020

Abstract
Background: Common variable immunodeficiency (CVID) is a heterogeneous group of primary immune deficiency disorders that may be characterized by heightened susceptibility to gastrointestinal (GI) infection. GI conditions manifest in 20 to 50% of CVID patients but rarely include cholangitis.
Methods/Results: This is a 61-year-old female, with a history of cholecystectomy and gastric bypass, who presented with recurrent ascending cholangitis for eight years. After a hepaticojejunostomy to correct a bile duct stricture complication from the cholecystectomy, ascending cholangitis was diagnosed by clinical presentation of fever and right upper quadrant pain and imaging revealing pneumobilia. CVID was diagnosed after no response to pneumococcal polysaccharide vaccine, as well as serum IgA and IgG measured below the normal ranges. The patient was prescribed a successful, weekly regimen of 15 g of oral intravenous immunoglobulin (IVIG) ten percent liquid (Gammaplex® 10%, 5 gm/50 mL).
Conclusion: Oral human IVIG is a novel treatment and has been infrequently utilized for management of chronic rotavirus, necrotizing enterocolitis, diarrhea, HIV enteropathy, irritable bowel syndrome, and malnutrition. This is the first case of recurrent ascending cholangitis as the primary manifestation of CVID, as well as successful treatment of this condition with oral IVIG, in the literature.
The role of inner values to teamwork during design for social innovation
Authors: YOUNG Robert , VYAS Pratik 
Published: January 2020

Professionals can increase their performance by improved actions but true change occurs when the underlying ‘inner values’ change. Applying a design process while working in teams during social innovation projects also requires certain ‘inner values’. Schön (1983) suggested reflection as a way to improve professional practice by challenging and changing the underlying value system. Various literature identifies different inner values, which are considered important for teamwork during design for social innovation (DfSI), however this is not systematic, evidence-based research. This paper presents such a study conducted in this context.
Firstly, this study presents a review of key literature, which leads to a list of inner values considered important by authors for DfSI. Secondly, a survey method collected quantitative and qualitative data from 29 expert design practitioners who reflected on their teamwork experience during DfSI. The survey showed that most experts apply the list of inner values from literature, yet their understanding demonstrates a variety of interpretation and application, leading to more questions than answers and revealing the complexity of DfSI. The survey also found that whilst many inner values play an important role, the trade-off between them is essential, requiring wisdom and balance by the designer.
Section 2.a Introduction
Authors: YUAN Soe-Tsyr , SUNG Tung-Jung , YUAN Lu 
Published: January 2020

It is widely recognized that Product-Service System (PSS) is a promising new business creation approach. In the digital era and with the rise of the service economy, PSS provides enterprises with additional approaches to create sustainable innovations and build competitive advantages. It mainly focuses on designing good experiences, establishing value networks among different stakeholders, creating new business models, and improving existing business models. Furthermore, PSS emphasizes service-dominant logic and the “use phase” of the product life cycle analysis.
Although the value of PSS has been widely recognized, there is still a lack of successful PSS innovative cases. Past research has noted that there are a lot of barriers and challenges when designing and implementing PSSs. In addition to understanding the user’s needs, wants, and desires, PSS design has to adopt a holistic view on value creation, scalable methods, value propositions integrating internal and external stakeholders, and organizational transformation. This section aims to offer a platform for practitioners and researchers to uncover compelling insights, discuss latest developments, and envision future directions for PSS design.
Cognitive Study of Products’ User Interfaces for Use by Elderly People
Authors: CHEN Li-Hao , WANG Chun 
Published: January 2020

This study investigated elderly users’ understanding of images and their perception of products. Various product function images served as testing samples, and participants were required to rank the various images. The results of this study revealed that the elderly participants easily recognized concrete images or images that were familiar. The elderly participants had various views concerning simplified images. Associative images that could not be associated with objects from daily life were not efficiently recognized. In the present study, we only explored the effect of shape and elements used on elderly people’s understanding of images. The results of this study can serve as a reference for designers when constructing a product’s user interface to be used by elderly people.
Educating Design Innovation Catalysts Through Design Interventions
Authors: MOSELY Genevieve , HAMMEL Raphael 
Published: January 2020

In the increasingly competitive and fast-changing business environment, innovation is a growing necessity. Organisations are seeking to leverage design as one way to deliver more value to their customers, although the use of design to innovate is still an emerging practice.
Individual capability underpins organisational adoption of design and as such the role (education and training) of this individual is currently under investigation – coined the ‘design innovation catalyst’. This paper describes a series of design interventions in a case study of a cohort of fifteen participants in an Australian industrial sector, which aimed to provide the foundation to educate participants about the role of design innovation catalysts. Based on this case study this paper makes a series of observations and reflections on the experience of these design innovation catalysts, which form the basis for recommendations to improve the effectiveness of future programs.
Consumption experience on Tmall
Authors: CHEN Zhen , CHEUNG Ming 
Published: January 2020

This article contributes to the methodology literature of experience design by analysing banner ads on Tmall with a synthesis of social semiotics, multimodal analysis, and interactivity which guides our analysis of consumer-oriented advertising in e-commerce. Departing from Tmall’s annual Double 11 Carnival, our analysis shows that the banner ads have been incorporated into a gamification design to encourage consumers to spend more and buy things they may not need even after the event has been completed. Our approach of analysing the ads on both the syntagmatic and paradigmatic dimensions is explicitly multimodal, taking the linguistic, visual and interactive resources (the tri-fold convergence) into consideration to study new phenomena in an e-selling environment. The approach of this study could be helpful to scholars and practitioners in the field of experience design, where multimodality and textual analysis of visual information is of great importance.
Colonizing Innovation:
Authors: CHATURVEDI Abhinav , REHN Alf 
Published: January 2020

Innovation is one of the most popular concepts and desired phenomena of contemporary Western capitalism. As such, there is a perennial drive to capture said phenomena, and particularly to find new ways to incite and drive the same. In this text, we analyze one specific tactic through which this is done, namely by the culturally colonial appropriation of indigenous knowledge systems. By looking to how jugaad, a system of frugal innovation in India, has been made into fodder for Western management literature, we argue for the need of a more developed innovation critique, e.g., by looking to postcolonial theory.
Developing and applying performance metrics to evaluate co-design activities in design-led innovation
Authors: O'HARE Jamie , DEKONINCK Elies , GIUNTA Lorenzo 
Published: January 2020

Abstract – An increasing number of companies are experimenting with ‘designerly ways of innovating’ to improve the agility, speed and hit rate of their innovation activities. Co-design activities are emerging as part of a design-led innovation approach. Whilst there is extensive academic literature on design process performance metrics, they have rarely been applied by organisations that are testing co-design activities, possibly due to the time and effort that is required to apply them. This paper begins to address this challenge by developing a tailored suite of design process performance metrics. Some basic guidelines from the academic literature and the results of a practitioner survey inform the selection of metrics. We go on to apply the metrics to real-world projects within companies that are trialling technology-supported co-creation sessions. The metrics and the insights into their development and application are likely to prove useful to other design researchers and practitioners that wish to evaluate the benefits of adopting co-design activities as part of a design-led innovation approach.
Forming Opportunities through Design Thinking
Authors: POTOCNJAK-OXMAN Camilo , KRIZ Anton , NAILER Christopher 
Published: January 2020

An interesting development in the entrepreneurial economy is the rise in both number and diversity of roles played by designers. Be it as consultants, contractors, educators, founders or funding decision-makers, design skills seem to be increasingly attractive to entrepreneurial teams, accelerator programs and venture capital. This exploratory study asks whether the practices, cognitive processes and mindsets prevalent in a formal design education help in the formation of entrepreneurial opportunities. Using a visual narrative approach, it compares the processes through which entrepreneurial opportunities were formed by 14 Chilean founders from design and non-design backgrounds, with the purpose of identifying how design thinking contributes to, hinders, or fails to support those processes. Findings suggest that collaborative work styles, thinking by doing and reflective reframing have the greatest positive impacts on opportunity formation, regardless of the disciplinary background of founders. Design thinking does not seem to provide a clear understanding of value creation and resource leveraging. The study finds parallels between design thinking and opportunity formation that can be drawn upon to improve development of entrepreneurial competencies among designers.
Decolonising Namibian Arts and Design through Improvisation
Authors: SARANTOU Melanie , BEAULÉ Caoimhe Isha , MIETTINEN Satu 
Published: January 2020

The research investigates the role of service design and improvisation as decolonising practice. It is based on case study research with a focus group consisting of Namibian artists, designers, artisans and arts organisations who participated in artistic and cultural exchange activities of the Art South-South Trust (ASST), a start-up Namibian not for profit (NFP) organisation. The goal of ASST was to increase visibility of the focus group members, enable global exposure and create an arena for multi-vocality. The paper creates a practical framework for decolonising practices in Namibian arts and design by drawing on reflective practice to analyse the activities of ASST alongside interview data collected from Namibian and Australian partner organisations and participants in the program. Critical thinking is used to evaluate the impact of realised activities and processes both in situ in Namibia and in exchange in Australia. This paper explores practices that can enable decolonising processes in Namibian arts and design spheres
Social innovation for modified consumption by means of the school subject Art and craft
Authors: NEUBERG Anita 
Published: January 2020

In this paper I will take a look at how one can facilitate the change in consumption through social innovation, based on the subject of art and design in Norwegian general education. This paper will give a presentation of books, featured relevant articles and formal documents put into context to identify different causal mechanisms around our consumption. The discussion will be anchored around the resources and condition that must be provided to achieve and identify opportunities for action under the subject of Art and craft, a subject in Norwegian general education with designing at the core of the subject, ages 6–16. The question that this paper points toward is:
"How can we, based on the subject of Art and craft in primary schools, facilitate the change in consumption through social innovation?”
Track 1.b Introduction: Re-Designing Health: Transforming Systems, Practices and Care
Authors: ROWE Aidana , JAENICHEN Claudine , HARVEY Gillian , SELLEN Kate , VANDENBERG Stephanie  
Published: January 2020

The Re-Designing Health: Transforming Systems, Practices and Care track explores the increasing role and possibility for a wide range of design practices and methods to contribute to health care products, provision, and systems.
There is growing recognition of the increasing complexity faced by healthcare systems; critical issues and challenges include ageing populations, chronic diseases, growing drug ineffectiveness, and lack of access to comprehensive services (to name only a few examples). Concurrently design thinking, methods and practices are increasingly recognized as means of addressing complex, multi-levelled and systemic problems.
The track session brought together design academics, researchers and practitioners that are working in—and across—areas of design, medicine and health. Employing design methods, practices, and thinking to address a range of healthcare challenges—from individual product to large-scale policy. This track provided a forum for researchers, practitioners, students, and designers to provide evidence for these relationships, document challenges and successes and to provide theoretical and practical models for healthcare and design to work collaboratively to address complex healthcare problems.
Track 3.b Introduction: Measuring and communicating the value of design
Authors: LANGHAM Jo’Anne , PAULSEN Neil , RAUTH Ingo , TERREY Nina , CHUDCZAK Chrystia 
Published: January 2020

Although design has become synonymous with innovation, a tool for good leadership and is seen as a critical factor in the success of many high performing organisations, it is still considered by many as a luxury that comes at the expense of stakeholder resources and speed to market. Many organisations must still be persuaded to employ design. Design strategy, or the politics of design, is emerging as a critical issue required to overcome the powerful forces that often inhibit the implementation of good design. Some organisations have attempted to measure design, but it is still an inconclusive practice. How do we make design impact, visible and measurable? How do designers convince decision makers of the tangible and enduring benefits of good design? How do organisations know that their designs are having the desired impact?
This track explored the theme of transforming business strategy, organisational practice and culture, influencing management decisions and impacting citizens through design evaluation. We were particularly interested in describing and providing metrics for the value of design. We were also looking to explore the ways that practitioners and academics have evaluated the success of design in organisations and society. The papers presented in this track were widely dispersed under this theme using a arrange of qualitative and quantitative research approaches.
Track 3.d Introduction: How does design express value?
Authors: KRISTENSEN Tore , HANDS David , CLEMENT Jesper , DICKSON Thomas , GABRIELSEN Gorm , JOO Jaewoo , MÜNSTER Mia 
Published: January 2020

A general view, often presented in a political context, suggests investment in design may create societal benefits, like economic growth, employment, competitiveness, and convenience. Conducted at a general level with aggregate variables, such measurements provide very limited insights and can even be misleading. A different approach takes a particular view of a designed artefact, object, system or service. Addressing the benefactors, users and consumers, we may be able to reach an individual value, which in turn may be aggregated to assess a market, KPI or similar.
How does design express value? And how can we measure the value?
To design is to create value for somebody. However, the value depends on who judges it and their and their personal values.
According to John Heskett;
“Design, stripped to its essence, can be defined as the human capacity to shape and make our environment in ways without precedent in nature that serves our needs and gives meaning to our lives”. (Heskett, 2005).
This suggests that artefacts, objects, systems and services, which are available to us, may influence and serve us in different ways depending on our position within a particular environment. Any artefact may affect our physical well-being. This reflects preferences and other values may essentially be emotions and feelings.
Track 4.c Introduction: Transformation IN and BY Design Thinking
Authors: BIANCHI Mattia , CANDI Marina , DELL’ERA Claudio , MAGISTRETTI Stefano , STIGLIANI Ileana , VERGANTI Roberto 
Published: January 2020

Scholars and practitioners are acknowledging the central role that design can play in innovation. Design is increasingly becoming a strategic source of competitive advantage, to the point that scholars investigate its managerial side and its impact in the creation of value. Design Thinking, in particular, is making the headlines, with an extremely rapid diffusion in the practice and interest of organizations. Far from being connected with the “form” of products, Design Thinking is accepted as a formal method for creative problem solving, with the intent to foster innovation.
This rapid adoption of Design Thinking in practice however has not gone hand in hand with a robust development and diffusion of its theoretical underpinnings. On the practitioner side, Accenture, Deloitte, IBM, KPMG, McKinsey and PricewaterhouseCoopers rank among the most forceful players in acquiring design agencies in order to renew their offering and refresh their approach. Contemporary design thinking is booming in those industries where the digital transformation requires new competences and capabilities for developing delightful digital experiences. On the one hand Design Thinking describes significant transformations highlighting overlaps and synergies with emerging approaches such Design Sprint, Agile or Creative Confidence; on the other hand it is considered a fundamental paradigm to lead digital transformations. For this reason, the thematic track “Transformation IN and BY Design Thinking” investigates the evolution of this paradigm in relation to different theoretical lenses:

Design Thinking and Innovation Theories
Design Thinking and Creativity Theories
Design Thinking and Leadership Theories
Design Thinking and Organizational Theories
Track 5.j Introduction: Innovation Through Design for Meaning
Authors: Ajovalasit Marco , Giacomin Joseph , Gkatzidou Voula , Jenson Bennett Julie , Pettersson Ingrid 
Published: January 2020

This track brings together researchers and practitioners to share and discuss the approach, subsequent outcomes, contributions and possible futures of the design for meaning landscape.
For many fast moving consumer goods, home goods, office goods, vehicles, transport systems and elements of the built environment there are a growing number of instances in which a business opportunity can only be achieved by exploiting a new technology or a new cultural code (Holt and Cameron, 2010). Such cases of disruptive innovation or radical innovation are premised on the possibility of defining a new meaning for the potential consumers. The idea that design is a manner for making sense of things is frequently discussed in professional circles, as is the idea that design involves doing philosophy with the hands (Wendt 2015). For many practicing designers the activity of design cannot be separated from the intended meanings of the artefact which is being designed.
Thinking-through-making
Authors: FRY Aaron 
Published: January 2020

Design thinking currently enjoys public recognition and is increasingly utilized in business consulting and strategic decision-making. It has given rise to university programs while opening up varied careers for design strategists. As design enters mainstream management consulting practice, a critical question being asked of educators, designers and businesses is what kind of design is privileged within design thinking-as-business strategy. Moreover, has this version of design thinking delivered additional creativity to business environments centred on process efficiency? Nussbaum (2011) argues that business has embraced a brand of design thinking that is recognizably process-oriented, and this has limited its capacity to deliver on its mission of enhancing business creativity.
This study examines a project delivered in the first semester of Parsons’ Master of Science in Strategic Design and Management program, it is called Understanding-through-making: building new dimensions in the new economy. This practical studio-based project requires students to physically build a model that exemplifies their understanding of the dynamics defining and driving business in the 21st Century. This project attempts to counter a scientific, process-oriented design thinking with a more beaux arts, craft-oriented, thinking-through-making approach. Currently student outcomes are varied; some exist as pedagogic devices while others are recognizable as tools (e.g., navigators and compasses).
The study analyses these current outcomes, highlights the shortcomings of both the current project and its outcomes and proposes possibilities for future iterations that promise to explore other paradigms in the application of design thinking to business.
Building Adaptable Teams for Co-configuration
Authors: FUTERMAN Rael Glen 
Published: January 2020

In innovative organisations we are seeing an increase in cross-functional teams being built around projects. The diverse perspectives of collaborators draw from personal world-views and organisational roles, which contributes to radical collaboration across traditional boundaries of work.
This hands-on workshop aims at testing a rapid team alignment activity in which teams propose core values and align these to the innovation learning cycle, synthesising them into foundational work practices for each phase. These are then reframed as the teams' innovation narrative.