bluuebunny/crossref_metadata_2025_split huggingface dataset:
On viability of detecting malwares online using ensemble classification method with performance metrics
Authors: Saranya N. , Manikandan V. 
Published: April 2020

AbstractNowadays, most of the services from cloud are protuberant within the all commercial, public, and private areas. A primary difficulty of cloud computing system is making a virtualized environment safe from all intruders. The existing system uses signature‐based methods, which cannot provide accurate detection of malware. This paper put forward an approach to detect the malware by using the approach based on feature extraction and various classification techniques. Initially the clean files and malware files are extracted. The feature selection includes gain ratio to provide subset features. The classification is used to predict any malware that has been entered in the mobile device. In this paper, it is proposed to use the ensemble classifier which contains different kinds of classifiers such as Support Vector Machine, K‐Nearest Neighbor, and Naïve Bayes classification. These together are known as a meta classifier. These three classification methods had been used for proposed work and get the results with higher accuracy. This measures the correctness of the prediction happened using ensemble method with high precision and recall values which is specifically identifies the quality of the techniques
used.
Whole‐exome sequencing reveals a long‐term decline in effective population size of red spruce (Picea rubens)
Authors: Capblancq Thibaut , Butnor John R. , Deyoung Sonia , Thibault Ethan , Munson Helena , Nelson David M. , Fitzpatrick Matthew C. , Keller Stephen R. 
Published: April 2020

AbstractUnderstanding the factors influencing the current distribution of genetic diversity across a species range is one of the main questions of evolutionary biology, especially given the increasing threat to biodiversity posed by climate change. Historical demographic processes such as population expansion or bottlenecks and decline are known to exert a predominant influence on past and current levels of genetic diversity, and revealing this demo‐genetic history can have immediate conservation implications. We used a whole‐exome capture sequencing approach to analyze polymorphism across the gene space of red spruce (Picea rubens Sarg.), an endemic and emblematic tree species of eastern North America high‐elevation forests that are facing the combined threat of global warming and increasing human activities. We sampled a total of 340 individuals, including populations from the current core of the range in northeastern USA and southeastern Canada and from the southern portions of its range along the Appalachian Mountains, where populations occur as highly fragmented mountaintop “sky islands.” Exome capture baits were designed from the closely relative white spruce (P. glauca Voss) transcriptome, and sequencing successfully captured most regions on or near our target genes, resulting in the generation of a new and expansive genomic resource for studying standing genetic variation in red spruce applicable to its conservation. Our results, based on over 2 million exome‐derived variants, indicate that red spruce is structured into three distinct ancestry groups that occupy different geographic regions of its highly fragmented range. Moreover, these groups show small Ne, with a temporal history of sustained population decline that has been ongoing for thousands (or even hundreds of thousands) of years. These results demonstrate the broad potential of genomic studies for revealing details of the demographic history that can inform management and conservation efforts of nonmodel species with active restoration programs, such as red spruce.
Size reductions and genomic changes within two generations in wild walleye populations: associated with harvest?
Authors: Bowles Ella , Marin Kia , Mogensen Stephanie , MacLeod Pamela , Fraser Dylan J. 
Published: April 2020

AbstractThe extent and rate of harvest‐induced genetic changes in natural populations may impact population productivity, recovery, and persistence. While there is substantial evidence for phenotypic changes in harvested fishes, knowledge of genetic change in the wild remains limited, as phenotypic and genetic data are seldom considered in tandem, and the number of generations needed for genetic changes to occur is not well understood. We quantified changes in size‐at‐age, sex‐specific changes in body size, and genomic metrics in three harvested walleye (Sander vitreus) populations and a fourth reference population with low harvest levels over a 15‐year period in Mistassini Lake, Quebec. We also collected Indigenous knowledge (IK) surrounding concerns about these populations over time. Using ~9,000 SNPs, genomic metrics included changes in population structure, neutral genomic diversity, effective population size, and signatures of selection. Indigenous knowledge revealed overall reductions in body size and number of fish caught. Smaller body size, a small reduction in size‐at‐age, nascent changes to population structure (population differentiation within one river and homogenization between two others), and signatures of selection between historical and contemporary samples reflected coupled phenotypic and genomic change in the three harvested populations in both sexes, while no change occurred in the reference population. Sex‐specific analyses revealed differences in both body size and genomic metrics but were inconclusive about whether one sex was disproportionately affected. Although alternative explanations cannot be ruled out, our collective results are consistent with the hypothesis that genetic changes associated with harvesting may arise within 1–2.5 generations in long‐lived wild fishes. This study thus demonstrates the need to investigate concerns about harvest‐induced evolution quickly once they have been raised.
Structural plasticity of a designer protein sheds light on β‐propeller protein evolution
Authors: Mylemans Bram , Laier Ina , Kamata Kenichi , Akashi Satoko , Noguchi Hiroki , Tame Jeremy R. H. , Voet Arnout R. D. 
Published: April 2020

β‐propeller proteins are common in nature, where they are observed to adopt 4‐ to 10‐fold internal rotational pseudo‐symmetry. This size diversity can be explained by the evolutionary process of gene duplication and fusion. In this study, we investigated a distorted β‐propeller protein, an apparent intermediate between two symmetries. From this template, we created a perfectly symmetric 9‐bladed β‐propeller named Cake, using computational design and ancestral sequence reconstruction. The designed repeat sequence was found to be capable of generating both 8‐fold and 9‐fold propellers which are highly stable. Cake variants with 2–10 identical copies of the repeat sequence were characterised by X‐ray crystallography and in solution. They were found to be highly stable, and to self‐assemble into 8‐ or 9‐fold symmetrical propellers. These findings show that the β‐propeller fold allows sufficient structural plasticity to permit a given blade to assemble different forms, a transition from even to odd changes in blade number, and provide a potential explanation for the wide diversity of repeat numbers observed in natural propeller proteins.DatabaseStructural data are available in Protein Data Bank database under the accession numbers 6TJB, 6TJC, 6TJD, 6TJE, 6TJF, 6TJG, 6TJH and 6TJI.
Institutional influence on syndicate structure and cross‐border leveraged buyouts
Authors: Liu Chen , Purda Lynnette , Zhu Hui 
Published: April 2020

AbstractWe explore the extent to which differences in countries’ formal and informal institutions reduce cross‐border leveraged buyout transactions and the potential influence these same institutions have on how private equity (PE) investors choose to enter these transactions. Although institutional differences have frequently been viewed as barriers to cross‐border investment, we find evidence that these same differences may motivate a PE firm's decision to enter the transaction with a syndicate of firms rather than undertaking the transaction on their own. Cultural differences between a PE firm and the target nation are significantly related to the choice to enter the deal via a multinational syndicate. The varying nationalities within the syndicate contribute to enhanced familiarity, with average institutional distances between the syndicate and target firms being significantly lower than for single‐PE‐led deals. Overall, deals undertaken by syndicates are more likely to be successfully completed and require less time in negotiation. These results persist even after accounting for selection bias with regard to target country choice. We explore whether other features of the syndicate are responsible for improved deal outcomes, such as repeated transactions with the same partners, but find no evidence that this is the case.
Effects of several establishment modes of Miscanthus × giganteus and Miscanthus sinensis on yields and yield trends
Authors: Ouattara Malick S. , Laurent Anabelle , Barbu Corentin , Berthou Magali , Borujerdi Elsa , Butier Arnaud , Malvoisin Pierre , Romelot Dominique , Loyce Chantal 
Published: April 2020

AbstractMiscanthus is a C4 perennial grass originating from East Asia, the yields of which progressively increase in the first years of growth. Several species for bioenergy have been studied since the mid‐1980s in Europe, in particular (Miscanthus × giganteus [M. × giganteus]), due to its high yields. M. × giganteus is mainly cultivated in France and established from rhizomes. Our study aimed to assess, in field conditions, alternative establishment methods combined with an alternative species, Miscanthus sinensis (M. sinensis). We set up a multi‐environment experimental network. On each trial, we tested two treatments with M. × giganteus, established from rhizomes (G_r‐sd) and from plantlets obtained from rhizomes (G_p‐sd), and two treatments with M. sinensis seedlings transplanted in single (S_p‐sd) and double density (S_p‐dd). ANOVA was performed to compare establishment and regrowth rates across treatments, as well as yields across treatments and site‐years. A logistic model was used to describe yield trends and to compare the maximum yield reached and the rate of yield increase of both species. Results showed that miscanthus establishment from plantlets resulted in higher establishment (between 87% and 92%) and regrowth (between 91% and 94%) rates compared to establishment from rhizomes. Treatments with M. × giganteus obtained higher average yields across site‐years than those with M. sinensis, but more variable yields across site‐years. We showed a strong species effect on yields, yield components (shoot weight, shoot density and shoot number per plant) and light interception (through leaf area index). Lastly, to use M. sinensis established from transplanted plantlets as an alternative to M. × giganteus, research would be required on the breeding of M. sinensis sterile seeds to avoid risks of invasiveness.
Genomic and morphological data help uncover extinction‐in‐progress of an unsustainably traded hill myna radiation
Authors: Ng Dominic Y. J. , Švejcarová Tereza , Sadanandan Keren R. , Ferasyi Teuku Reza , Lee Jessica G.H. , Prawiradilaga Dewi M. , Ouhel Tomáš , Ng Elize Y.X. , Rheindt Frank E. 
Published: April 2020

The Asian songbird crisis which is currently unfolding in Southeast Asia has seen multiple bird taxa go extinct in the wild and even more slip into regional or local extinction over the span of only a few years. The hill mynas Gracula spp. are among its main victims, encompassing the Critically Endangered Nias Hill Myna Gracula [religiosa] robusta and other endangered populations across the West Sumatran Archipelago. Hill mynas are known to be present throughout this island chain but the taxonomic relationships of West Sumatran Gracula populations remain poorly understood. We hypothesized that the unique history of this island chain may have given rise to multiple distinct insular forms. Here we use genome‐wide DNA data in concert with morphological analyses to investigate the evolutionary distinctness of these taxa. Our results identify one taxon that is surprisingly distinct despite lacking recognition in most classifications, the ‘Simeulue Hill Myna’ (taxon miotera), and a range extension of the Nias Hill Myna. Despite their lack of recognition, Simeulue Hill Mynas are genomically and morphologically as unique as their Nias counterpart, in accordance with the lack of glacial land bridges between the island of Simeulue and mainland Sumatra. Simeulue Hill Mynas went extinct in the wild sometime within the last 2–3 years, and the rescue of the last captive individuals should now be the highest priority.
Prevalence and predictive value of ICD‐11 post‐traumatic stress disorder and Complex PTSD diagnoses in children and adolescents exposed to a single‐event trauma
Authors: Elliott Rachel , McKinnon Anna , Dixon Clare , Boyle Adrian , Murphy Fionnuala , Dahm Theresa , Travers‐Hill Emma , Mul Cari‐lène , Archibald Sarah‐Jane , Smith Patrick , Dalgleish Tim , Meiser‐Stedman Richard , Hitchcock Caitlin 
Published: April 2020

BackgroundThe 11th edition of the International Classification of Diseases (ICD‐11) made a number of significant changes to the diagnostic criteria for post‐traumatic stress disorder (PTSD). We sought to determine the prevalence and 3‐month predictive values of the new ICD‐11 PTSD criteria relative to ICD‐10 PTSD, in children and adolescents following a single traumatic event. ICD‐11 also introduced a diagnosis of Complex PTSD (CPTSD), proposed to typically result from prolonged, chronic exposure to traumatic experiences, although the CPTSD diagnostic criteria do not require a repeated experience of trauma. We therefore explored whether children and adolescents demonstrate ICD‐11 CPTSD features following exposure to a single‐incident trauma.MethodData were analysed from a prospective cohort study of youth aged 8–17 years who had attended an emergency department following a single trauma. Assessments of PTSD, CPTSD, depressive and anxiety symptoms were performed at two to four weeks (n = 226) and nine weeks (n = 208) post‐trauma, allowing us to calculate and compare the prevalence and predictive value of ICD‐10 and ICD‐11 PTSD criteria, along with CPTSD. Predictive abilities of different diagnostic thresholds were undertaken using positive/negative predictive values, sensitivity/specificity statistics and logistic regressions.ResultsAt Week 9, 15 participants (7%) were identified as experiencing ICD‐11 PTSD, compared to 23 (11%) experiencing ICD‐10 PTSD. There was no significant difference in comorbidity rates between ICD‐10 and ICD‐11 PTSD diagnoses. Ninety per cent of participants with ICD‐11 PTSD also met criteria for at least one CPTSD feature. Five participants met full CPTSD criteria.ConclusionsReduced prevalence of PTSD associated with the use of ICD‐11 criteria is likely to reduce identification of PTSD relative to using ICD‐10 criteria but not relative to DSM‐4 and DSM‐5 criteria. Diagnosis of CPTSD is likely to be infrequent following single‐incident trauma.
Nudging clinicians: A systematic scoping review of the literature
Authors: Lamprell Klay , Tran Yvonne , Arnolda Gaston , Braithwaite Jeffrey 
Published: April 2020

AbstractBackgroundWhile the quality of medical care delivered by physicians can be very good, it can also be inconsistent and feature behaviours that are entrenched despite updated information and evidence. The “nudge” paradigm for behaviour change is being used to bring clinical practice in line with desired standards. The premise is that behaviour can be voluntarily shifted by making particular choices instinctively appealing. We reviewed studies that are explicit about their use of nudge theory in influencing clinician behaviour.MethodsDatabases were searched from April 2008 (the publication date of the book that introduced nudge theory to a wider audience) to November 2018, inclusive. The search strategy and narrative review of results addressed the Preferred Reporting Items for Systematic reviews and Meta‐Analyses extension for Scoping Reviews.Results22 studies were identified. Randomized trials or pre‐post comparisons were generally used in community‐based settings; single‐site pre‐post studies were favoured in hospitals. The studies employed eight intervention types: active choice; patient chart redesign; default and default alerts; partitioning of prescription menus; audit and feedback; commitment messages; peer comparisons; and redirection of workflow. Three core cognitive factors underpinned the eight interventions: bias towards prominent choices (salience); predisposition to social norms; and bias towards time or cost savings.ConclusionsPublished studies that are explicit about their use of nudge theory are few in number and diverse in their settings, targets, and results. Default and chart re‐design interventions reported the most substantial improvements in adherence to evidence and guideline‐based practice. Studies that are explicit in their use of nudge theory address the widespread failure of clinical practice studies to identify theoretical frameworks for interventions. However, few studies identified in our review engaged in research to understand the contextual and site‐specific barriers to a desired behaviour before designing a nudge intervention.
High resolution multispectral endoscopy significantly improves the diagnostic accuracy of cervical intraepithelial lesions
Authors: Yu Wen , Long Cai , Zhu Tailin , Zhu Huiting , Han Zhiqiang , Li Fang 
Published: April 2020

AbstractColposcopy is a visual technique to examine the cervix and determine selection of sites for biopsies and eligibility for treatment. It's always been a critical part of identifying preinvasive and early invasive cervical carcinoma. Unfortunately, challenges exist with regards to the accuracy of traditional colposcopy. Hence, to fully exploit the benefit of increasing diagnostic sensitivity, there is a pressing need to improve the performance of colposcopy by applying novel innovations and techniques. In this case report, we used a recently developed, high‐resolution multispectral endoscopy and evaluated its performance by comparing colposcopic image features (the vascular pattern, in particular, depending upon the improved optics and illumination) with histology results. High‐resolution multispectral endoscopy makes it easier to distinguish the features of pathological vessels, so that it has a higher sensitivity and specificity to detect cervical lesions, especially in discriminating the vascular pattern using multispectral technology.
In ovo injection of nano‐selenium spheres mitigates the hatchability, histopathology image and immune response of hatched chicks
Authors: El‐Deep Mahmoud H. , Amber Khairy A. , Elgendy Salwa , Dawood Mahmoud A. O. , Zidan Abdulrahman 
Published: April 2020

AbstractIn ovo injection of nano‐selenium (Se) produced by lactic acid bacteria (LAB–nano‐Se) was investigated on the hatchability, immune responses and the histopathological alterations in hatched chicks. The eggs (18 day age) were injected with 0.5 ml of 0.9% NaCl (normal saline, NS), while the control group was kept without injection. In the third, fourth and fifth groups, the eggs were injected with 0.5 ml of NS and LAB–nano‐Se at 10, 20 and 30 μg/egg. The results revealed improved growth performance in groups injected with LAB–nano‐Se when compared to the control treatment. The highest final weight and weight gain were noticed in 20 μg LAB–nano‐Se/egg group (p < .05). The feed conversion ratio was reduced in all treated groups when compared to the control group (p < .05). Groups injected with LAB–nano‐Se showed enhanced hatchability of the whole incubated eggs (p < .05). Total lipids and cholesterol levels were decreased significantly in groups treated with LAB–nano‐Se at 10 and 20 μg/egg when compared to the non‐treated group. At the same time, globulin was increased by LAB–nano‐Se in ovo injection. Furthermore, the total antioxidant capacity, catalase, glutathione peroxidase, superoxide dismutase increased in groups treated with LAB–nano‐Se at 10 and 20 μg/egg with insignificant (p > .05) differences with those treated with LAB–nano‐Se at 30 μg/egg using in ovo injection technique. Also, higher total blood protein and phagocytosis were significantly observed in groups treated with at 10, 20 and 30 μg LAB–nano‐Se/egg. The histopathological images of hatched chicks revealed that nano‐Se presented normal effects on liver and kidney tissues and restored the parameters as mentioned earlier. To conclude, LAB–nano‐Se exhibited beneficial effects in hatched chicks through improving immune and antioxidant activities as well as histopathological effects by using in ovo technique.
PHILOSOPHY AS A FEMINIST SPIRITUALITY AND CRITICAL PRACTICE FOR MARY ASTELL
Authors: Webb Simone 
Published: April 2020

AbstractThe question of how gender might inflect and affect philosophy as a way of life has been somewhat neglected, as has the role of philosophical modes of living for historical female philosophers. This essay draws on Michel Foucault’s multifaceted, Hadot‐inspired conception of philosophy to show how transformative philosophical practices of the self function as feminist praxis in the work of the early modern feminist philosopher Mary Astell. Philosophy in Astell’s texts, the essay argues, is a spiritual practice of the self that at the same time functions as a feminist critique both of sexist social structures and of the self that undertakes the practice. It facilitates women in achieving internal freedom. Finally, the essay discusses potential feminist concerns about Astell’s proposed philosophical way of living, before suggesting that it may have value for women today.
WHAT IT TAKES TO LIVE PHILOSOPHICALLY: OR, HOW TO PROGRESS IN THE ART OF LIVING
Authors: Cohoe Caleb M. , Grimm Stephen R. 
Published: April 2020

AbstractThis essay presents an account of what it takes to live a philosophical way of life: practitioners must be committed to a worldview, structure their lives around it, and engage in truth‐directed practices. Contra John Cooper, it does not require that one’s life be solely guided by reason. Religious or tradition‐based ways of life count as truth directed as long as their practices are reasons responsive and would be truth directed if the claims made by their way of life are correct. The essay argues that these three conditions can be met by progressors as well as sages. Making progress in how one acts in the world, and improving one’s understanding and direction through being part of a community is living a philosophical way of life. The offered view acknowledges more ways to develop the art of living and enables a broader range of people to count as living philosophically.
An integrated simulation method for coupled dynamic systems
Authors: Huang Xu , Kwon Oh‐Sung 
Published: April 2020

AbstractPartitioned methods have been widely used in multiphysics and large‐scale structure‐media problems since they allow decomposition of a complex system into smaller subsystems. Although they have been considered to be superior to monolithic methods in terms of software reuse, difficulties still exist in the implementation process. This paper addresses these difficulties and proposes a new method to ease the coupling of the dynamic subsystems analyzed with different finite element codes. This is enabled by the development of a new staggered approach such that each involved program acts as a black box that is accessible only through model input and output, that is, displacements and forces, at the interface boundary. The accuracy and stability of the proposed method are numerically evaluated. A practical method to determine the maximum time step for stable solutions is also proposed. Two application examples are presented to verify the algorithm and demonstrate potential of the proposed method.