bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Connective Tissue Graft and Platelet Rich Fibrin as Matrices in A Novel Papillary Augmentation Access: A Randomized Controlled Clinical Trial
Authors: Abirami T. , Subramanian Sangeetha , Prakash P. S.G. , Victor D. J. , Devapriya A. M. 
Published: December 2019

Abstract
Objective The present study was a randomized controlled clinical trial with the aim of evaluating the increase in papillary height and reduction in black triangle height obtained by the novel papillary augmentation access with either connective tissue graft (CTG) or platelet-rich fibrin (PRF) as matrix from baseline to 6 months.
Materials and Methods A total number of 20 sites with Nordland and Tarnow’s Class I, I-II and II interdental papillary loss were recruited into the study. The sites were randomly allocated with 10 sites per group into either: Group A (control group) or Group B (test group) which utilizes the same technique with CTG or PRF as matrix, respectively. The clinical parameters such as PPD (probing pocket depth) and CAL (clinical attachment level) at the surgical site, plaque score (FMPS), bleeding scores (FMBS), interdental papillary height (PH) and black triangle height (BTH), along with visual analog score by dentist (VAS-D) and by patient (VAS-P) were evaluated at baseline and at 6 months.
Results In both CTG and PRF groups, all the primary and secondary outcome variables such as PH, BTH, VAS-D and VAS-P showed statistically significant improvement from baseline to 6 months (p ≤0.05) within the group. On comparison at 6 months, there were no differences in the papillary height between the groups. However, the BTH has significantly reduced in the CTG group than the PRF group. Similarly, the VAS-D significantly improved in the CTG group than the PRF group (p = 0.010) at 6 months.
Conclusion The study demonstrates that the proposed papillary augmentation access with CTG and PRF was successful in managing the unaesthetic interdental papillary loss, with CTG showing better results in terms of reduction of black triangle than PRF.
Superficial radial artery - a rare variation and its clinical significance
Authors: PK Sankaran , Raghunath Gunapriya , R. Sathyan ,   Parimelazhagan
Published: December 2019

AbstractDuring routine dissection of upper limb, a variation in the origin of radial artery was observed in a female cadaver of about 60 years. The radial artery is usually a smaller terminal branch of the brachial artery in the forearm. On the right side of the cadaver the radial artery was found to originate from second part of the axillary artery, whereas on the left side the origin of radial artery was found to be normal. This variant of radial artery has been rarely documented in literature. Accurate anatomy of radial artery and its variations have definite diagnostic, interventional, and surgical significance.
Influence of Different Composites and Polishing Techniques on Periodontal Tissues near Noncarious Cervical Lesions: A Controlled, Randomized, Blinded Clinical Trial
Authors: Teixeira Nancielli , Webber Mariana Benedetti Ferreira , Nassar Carlos Augusto , Camilotti Veridiana , Mendonça Marcio José , Sinhoreti Mario Alexandre Coelho 
Published: December 2019

Abstract
Objectives This study evaluated the long-term effect on gingival tissues near noncarious cervical lesions after restoration with different composites in association with two different polishing techniques.
Materials and Methods This study was conducted on 60 patients as a randomized, split-mouth, single-blind clinical trial and divided into four groups (n = 15) and restored using different composites (Tetric N-Ceram nanohibride or Z350 XT nanoparticles) and polishing materials (Astropol or Sof-Lex). The periodontal parameters analyzed were Silness–Löe plaque index; Silness–Löe gingival index; probing depth, clinical insertion level; and bleeding on probing. Periodontal analysis was performed before scaling and root planing at 30, 60, 120, and 180 days after restoration.
Statistical Analysis The data submitted to the Friedman’s test were employed for comparison between groups (p < 0.05).
Results Statistically significant differences between Z350/Astropol and other groups were observed for visible plaque and probing depth. Gingival index Tetric/Sof-Lex, the time factor did not influence the results. All experiment groups exhibited statistically significant differences in the clinical level of insertion when the follow-up time was considered. Percentage of bleeding on probing, in which there was a difference only with regard to group Tetric/Sof-Lex when the time factor was considered.
Conclusion The evaluated composites and polishing techniques did not exhibit differences in performance in the periodontal parameters analyzed at the end of 6 months of evaluation.
Addition of docosahexaenoic acid synergistically enhances the efficacy of apatinib for triple-negative breast cancer therapy
Authors: Ma Yingjie , Yu Junxian , Li Qin , Su Qiang , Cao Bangwei 
Published: December 2019

ABSTRACT
The current study aimed to investigate the antitumor and antiangiogenesis effects of apatinib in triple-negative breast cancer in vitro and also whether the combination of docosahexaenoic acid (DHA) and apatinib is more effective than apatinib monotherapy. The cell counting kit-8 assay was used to measure cell proliferation. Flow cytometry was utilized to determine the cell apoptosis rate. A wound healing assay was utilized to assess cell migration. Western blot analysis was carried out to determine the effects of apatinib and DHA on Bcl-2, BAX, cleaved caspase-3, caspase-3, phosphorylated protein kinase B (p-Akt), and Akt expression. DHA in combination with apatinib showed enhanced inhibitory effects on cell proliferation and migration compared with apatinib or DHA monotherapy. Meanwhile, DHA combined with apatinib strongly increased the cell apoptosis percentage. DHA was observed to enhance the antitumor and antiangiogenesis effects of apatinib via further downregulation of p-Akt expression.
Abbreviations: FITC: fluorescein isothiocyanate; PI: propidium iodide
A single amino acid substitution in the FAD-binding domain causes the inactivation of Propionibacterium Acnes isomerase
Authors: Rao Yu , Li Shi-Li , Li Mei-Juan , Cui Sheng , Gou Ke-Mian 
Published: December 2019

ABSTRACT
We previously demonstrated the efficient production of trans 10, cis 12-conjugated linoleic acid (t10c12-CLA) in Lactococcus lactis by ectopically expressing a Propionibacterium acnes isomerase (pai) gene and also mentioned that a recombinant strain was unable to accumulate t10c12-CLA product, despite the normal transcription. Here, the molecular analysis indicated that this mutated strain harbors a pai gene with a single-nucleotide mutation converting GC50A to GTA, leading to a corresponding change of Alanine residue into Valine. The expression of the reverse mutation resulted in the recovery for enzyme activity. Site-directed mutagenesis indicated that the codon usage of Val17 was not responsible for the enzyme inactivation in the Ala17Val mutation. Western blot analysis revealed that the recombinant PAI protein was not detectable in the His tag-marked Ala17Val mutant. It is, therefore, reasonable to assume that Ala17 residue is critical for PAI functionality.
Abbreviations: pai: propionibacterium acnes isomerase; CLA: conjugated linoleic acid; t10c12-CLA: trans 10, cis 12-CLA; LA: linoleic acid (18:2n-6); FAD: flavin adenine dinucleotide
On a new SIMVW epidemic model with vaccination and endemic testing
Authors: Fernandez-Pereda J. , De la Sen M. , Alonso-Quesada S. 
Published: December 2019

Abstract
A new epidemic model referred to as SIMVW is proposed which includes the following subpopulations: susceptible human, infectious human, susceptible vector, infectious vector and vaccinated human. The transmission vector is the anopheles mosquito for the malaria disease. The disease-free equilibrium points concerning the absence of infection in humans and/or mosquitoes are defined and discussed from a stability point of view. A set of simulated examples are performed mainly related to typical endemic situations which are tested for a malaria case study in the absence and in the presence of vaccination efforts. The vaccination efforts delete susceptible numbers which are transferred to the vaccinated subpopulation and include online feedback information on the susceptible subpopulation to adjust the control effort. The vaccination effects are mainly to improve the convergence rates to the equilibrium point, to decrease the numbers of susceptible individuals while increasing those of recovered ones and to reduce the basic reproduction number so that the range of stability of the disease-free equilibrium points is larger compared to the case of absence of vaccination.
Structural design and development of a water transfer sample
Authors: Chen Yongguo , Chen Yonghua , Liu Qingkui 
Published: December 2019

Abstract
Understanding rare suspended particulate matter (including planktonic microorganisms) in the deep ocean is important but difficult to sample, for which we deigned a large-sized in-situ water sampler (200-1000L), i.e., a large volume water transfer system sampler. The system comprises of a deep-ocean pump, a filtering device, data acquisition and control devices, a supporting frame, a power supply component, a connecting mechanism, and a flow meter, etc. The filtering device integrates membranes for three-graded filtration at 0.22, 1, and 5μm, and an additional membrane aperture upon the need. The control device adopts two working modes: depth trigger and time trigger. The system can be added with a CTD and a fluorescence meter, etc. In addition, for a stationed site survey, several sets (such as 3 sets) of the system can be fixed at an interval on the suspension cable to work at different depths simultaneously. The system can be applied for high-level multi-layer filtration to obtain suspended particles. The system has been applied in several marine expeditions. The development of this system provides an ideal tool for deep-ocean in-situ sampling technology in China. The applications of the large volume water transfer system sampler for in-situ sampling in deep-ocean have been launched for a few times. Some interesting phenomena have been discovered and the advantages of in situ sampling are proved.
A new risk probability calculation method for urban ecological risk assessment
Authors: Liu Changfeng , Chen Weiping , Hou Ying , Ma Lingchao 
Published: December 2019

Abstract
The ecological risk associated with urbanization is of great concern where multiple stressors and risk receptors co-exist. Probabilistic risk characterization methods were rarely applied in past urban ecological risk assessments because of the difficulties in the derivation of theoretical probability distribution functions and the definite integral calculation. Therefore, we proposed a new method which is based on computer simulation and able to facilitate the calculation of risk probabilities. This method quantifies multiple ecological risk-related indicators using ecological models, implements Monte Carlo simulation to calculate the risk probability of single indicators, and applies the copula model to calculate the joint risk probability of multiple indicators. We conducted an assessment of urban ecological risk related to urban surface water environment in Beijing as a case study to validate this method. The results show that the means of surface runoff risk probability, total nitrogen pollutant load risk probability, and comprehensive (joint) risk probability were 0.33, 0.44, and 0.23, respectively, in the areas within Beijing Sixth Ring Road. All three types of risk were at moderate levels in the study areas, but exhibited high spatial heterogeneity and urban–suburban gradient. The average contributions of the three risk types were 25% (surface runoff risk), 32% (total nitrogen pollutant load risk), and 43% (comprehensive risk), indicating that the joint risk was overall the major risk type. In conclusion, our method considering multiple indicators and their probabilistic attributes can handle the uncertainties in ecological models and thus has potential to evaluate different types of urban ecological risks.
Improved estimates of mangrove cover and change reveal catastrophic deforestation in Myanmar
Authors: De Alban Jose Don T , Jamaludin Johanness , Wong de Wen Donovan , Than Maung Maung , Webb Edward L 
Published: December 2019

Abstract
Mangroves are one of the world’s most threatened ecosystems, and Myanmar is regarded as the current mangrove deforestation hotspot globally. Here, we use multi-sensor satellite data and Intensity Analysis to quantify and explain patterns of net and gross mangrove cover change (loss, gain, persistence) for the 1996–2016 period across all of Myanmar. Net national mangrove cover declined by 52% over 20 years, with annual net loss rates of 3.60%–3.87%. Gross mangrove deforestation was more profound: 63% of the 1996 mangrove extent had been temporarily or permanently converted by 2016. Rice, oil palm, and rubber expansion accounted for most conversion; however, our analysis revealed targeted systematic transitions of mangroves to water (presumably aquaculture) and built-up areas indicated emerging threats for mangroves from those land uses. Restoration programmes facilitated mangrove gains and represent a critical area for investment alongside protection. This study demonstrates the importance of multi-sensor satellite data for national-level mangrove change assessments, along with gross land cover transition analyses to assess landscape dynamics as well as prioritise threats and interventions in an effort to develop holistic strategies that aim to conserve important habitats.
Adsorption of Methylene Blue onto a Low-Cost And Environmental Friendly Goethite
Authors: Kharisma D , Abidin Z , Kusmana C 
Published: December 2019

Abstract
The commercial adsorbent has been widely used for dye removal, but it is non-economical. The objective of this study is to synthesize a low-cost and environmental friendly goethite as an adsorbent for methylene blue removal from aqueous solution using a batch-adsorption technique. Goethite was synthesized by adding sodium hydroxide to iron salt and aging at 40 °C for 7 and 21 days, then characterized by Infrared spectroscopy (FTIR) and x-ray diffraction (XRD). The results showed that the optimum concentration of adsorbed methylene blue was 300 mg/L with an adsorption capacity of 82.81 and 75.8 mg/g for GPA7 and GT7, respectively. The equilibrium data fit the Langmuir isotherm model with correlation efficient higher than 0,99. Based on cost analysis, GT7 was the cheapest adsorbent, compared to GPA7 and commercial goethite.
The effect of distance of noise level in a residential area (case study: residential area that close to Jagorawi highway and Pandu Raya road in Bogor City)
Authors: Widasari D , Fatimah I S , Nasrullah N 
Published: December 2019

Abstract
Bogor city is a city that continues to experience in population growth and physical city development, where the development creates various kinds of problems, which one is noise. This study aim to measure the noise level and analyse the influence of noise level and house distance from noise sources. Data retrieval was collected for three days a week. In one day, noise measurement was carried out for 16 hours (06.00 – 22.00) by measuring the sound pressure level for 10 minutes for each 27 measurement points. The results showed that the noise level in weekdays higher than weekend, with averaged 87.25 dB. In accordance with standard, the noise level of residential area is 55 dB, it means the noise level is above the noise threshold. Based on the regression analysis, the R square of housing is 0.76, the linear equation is Y = 77.656 – 6.292x. The study concluded that the distance affects the value of noise, the closer to the noise source the greater the noise value.
Ambient concentration of soil heavy metals in Indonesian tertiary and quaternary geologic formations: an explorative study
Authors: Iskandar  , Darmawan  , Sudadi U , Mulyanto Budi 
Published: December 2019

Abstract
In natural conditions, heavy metals in soils are inherited from rocks and minerals weathering. This study aims to determine the ambient concentration of heavy metals in soils developed from several rock types from tertiary and quaternary geological formations and their relationships. Composite soil samples were taken at 0-30 cm depth in sites far away from anthropogenic contamination of heavy metals, roads, and lands where solid and liquid wastes were probably discharged. Total concentrations of Aqua Regia extracted soil Cd, Cr, Cu, Ni, Pb and Zn were determined by AAS. Soil mineral types and amount in sand fraction were determined by polarization microscopy. The overall ambient total concentrations of soil Cd, Cr, Cu, Ni, Pb, and Zn in mg.kg−1 were 2.0-19.7; 0.4-5.3; 1.1-73.3; 0.9-30.5; 17.8-62.9; and 8.1-419.5, respectively. The relationship between soil minerals and ambient concentrations of these metals was unclear. However, among the soil samples analysed, high concentrations in mg.kg−1 of Cd (10.5-19.7) were found in soils developed from clay and sand sedimentary and intermediary volcanic tuff rocks, Ni (15.0-30.5) in soils on andesitic-basaltic and volcanic tuff rocks, Pb (57.4-62.9) in soils on granitic rocks, and Zn (119.6-419.5) in soils on andesitic-basaltic rocks, while for Cr and Cu was spread evenly across all parent rock types.
Sustainability of garlic cultivation at Tegal Regency, Central Java Province, Indonesia
Authors: Mar’atusholikha V , Widiatmaka  , Firmansyah I 
Published: December 2019

Abstract
Indonesia is an agricultural country that produces any agricultural product. Garlic is one of the horticulture products that are currently cultivated vastly. According to the national garlic development plan by the Ministry of the Agriculture of the Republic of Indonesia, the way to obtain self-sufficiency in garlic is developing seed centers and import arrangements. The objective of this research is to analyze the sustainability of garlic farming and to determine the leverages factors for garlic development. The study was conducted in Tegal, which is one of the central of Garlic Development in Central Java Province. The methodology used is analysis using Multidimensional Scaling (MDS). There are 43 attributes of 5 dimensions involved in the study, which are ecology, economic, social, infrastructure, and legal-institutional aspect. The result of the research showed that Garlic cultivation has a status as sustainable, with a sustainability index value of 66.44. The leverage factors that affect garlic development are pesticide use, waste management, planting plan, consumption level, productivity, labor efficiency scheme, land management, community empowerment, agriculture extension, storage technology, access to technology, marketing institution, and implementation of land conversion regulations.
The peak runoff model based on Existing Land Use and Masterplan in Sentul City area, Bogor
Authors: Suheri A , Kusmana C , Purwanto M Y J , Setiawan Y 
Published: December 2019

Abstract
This research aimed to create a peak runoff mode based on existing land use (LU) and masterplan in Sentul City area. To determine the peak runoff by rational method, the study uses the formulation as follows: Q = 0.2778.C.I.A, in which Q is the peak runoff, C is the runoff coefficient of area, I is the average rain rate intensity, and A is the area of study. For recognizing the existing LU, the researcher used image analysis SPOT-6 (2017) by supervised classification. It estimated the gamma distribution parameter through the maximum likelihood method by using software QGIS 2.8, SAGA GIS, dan Arc-GIS 10.4.1. According to the analysis, the study result showed the existing LU peak runoff coefficient value and masterplan are 0.40 and 0.61, respectively, in which the difference is 0.21. The peak runoff increase is 25.32 m3/sec or 6,622,560 m3/year as the impact of land-use change.
The Development of Households Sanitation in Indonesia: the Year of 2010-2018
Authors: Munandar Y 
Published: December 2019

Abstract
This study aims to find out how the development of household sanitation in Indonesia from 2010 to 2018. This study uses a descriptive analysis method using secondary data in the form of 2010 and 2018 SUSENAS compiled by BPS Indonesia and processed using Stata 2014 software. The development of household sanitation is proxied by the development of defecation facilities in households in Indonesia in 2010-2018. The result of the study is that the development of sanitation in Indonesia in the period of 2010-2018 is improving. This study concludes that the development of household sanitation in Indonesia from 2010 to 2018 is improving. This study recommends that the government strengthen its efforts in improving sanitation in Indonesia because in 2018 there are still 6,985,572 households that do not have defecation facilities so that they do open defecation which has a bad impact on environmental health.
Morphological diversity of F1 population in Anthurium through conventional breeding
Authors: Kurniati R , Yuniarto K , Kartikaningrum S 
Published: December 2019

Abstract
Anthurium genetic variability enhanced through conventional breeding. The objectives of the research were to obtain (1) morphology variation of the F1 population, and (2) selected clones from F1 population-based on morphology flower. Anthurium CV. Putri Gunung and Alvin were used as breeding parents. Anthurium CV. Putri Gunung as female parents and Alvin as male parents. The specific character of anthurium CV. Putri Gunung is potted anthurium with a red spathe. The color of anthurium cv. Alvin is white. Anthurium cv Alvin is also potted anthurium. There were 18 individual plants and 3 selected clones based on the color and size of flower in the F1 population. The F1 population was potted plant divided into categories, small and mini flower based on spathe size. There was some variation in spathe and spadix. Morphological variation based on the color of spathe and spadix and size of the flower.
Diversity of fauna as one of indicator of forest management in Tahura Wan Abdul Rachman
Authors: Dewi B S , Harianto S P , Febryano I G , Rahmawati D I , Dewara N , Tokita N , Koike S 
Published: December 2019

Abstract
Taman Hutan Raya Wan Abdul Rachman (Tahura WAR) is located at Lampung Province, Indonesia. University of Lampung as the state university has mandatory around 1.134 hectare to manage from Tahura WAR as Forest Education. Research has been done in this area. The purpose of the research is identifying biodiversity of fauna in Forest Education of University of Lampung at Tahura WAR. The research has been done from March to May 2018 (dry season) and October to December 2018 (rainy season). Each month collected data was consisted of six days observation. The method of the research is using traps, it is to lay the traps on the surface of soil by plastic bucket, with 72 traps at different location that separated by study site. The research result were found big black ants, small black ants, mosquitoes, millipedes, crickets, spiders, termites, snails, glomerides, small red ants, big red ants, frogs, small scorpion, caterpillar and dung beetle. Diversity Index of Shannon Wienner classified Tahura WAR as moderate which indicate the forest has good maintain as the aspect of ecology and the aspect of sustained of forest.