bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genomic properties of variably methylated retrotransposons in mouse
Authors: Elmer Jessica L. , Hay Amir D. , Kessler Noah J. , Bertozzi Tessa M. , Ainscough Eve , Ferguson-Smith Anne C. 
Published: October 2020

AbstractTransposable elements (TEs) are enriched in cytosine methylation, preventing their mobility within the genome. We previously identified a genome-wide repertoire of candidate intracisternal A particle (IAP) TEs in mice that exhibit inter-individual variability in this methylation (VM-IAPs) with implications for genome function. Here we validate these metastable epialleles and discover a novel class that exhibit tissue specificity (tsVM-IAPs) in addition to those with uniform methylation in all tissues (constitutive- or cVM-IAPs); both types have the potential to regulate genes incis. Screening for variable methylation at other TEs shows that this phenomenon is largely limited to IAPs, which are amongst the youngest and most active endogenous retroviruses. We identify sequences enriched within cVM-IAPs, but determine that these are not sufficient to confer epigenetic variability. CTCF is enriched at VM-IAPs with binding inversely correlated with DNA methylation. We uncover dynamic physical interactions between cVM-IAPs with low methylation ranges and other genomic loci, suggesting that VM-IAPs have the potential for long-range regulation. Our findings indicate that a recently evolved interplay between genetic sequence, CTCF binding, and DNA methylation at young TEs can result in inter-individual variability in transcriptional outcomes with implications for phenotypic variation.
Promoting effectiveness of “working from home”: findings from Hong Kong working population under COVID-19
Authors: Wong Ada Hiu Kan , Cheung Joyce Oiwun , Chen Ziguang 
Published: October 2020

PurposeWorking-from-home (WFH) practice has been adopted by many companies of a variety of industries in a diverse manner; however, it is not until the recent outbreak of the coronavirus disease 2019 (COVID-19) pandemic WFH gains worldwide popularity. With so many different views out there and based on work–family balance theory, this study aims to find out the factors which affect peoples' WFH effectiveness and whether they want the extended WFH practice when the pandemic crisis is over.Design/methodology/approachThis paper adopted an online survey approach by posting questionnaires on the university website and different social media channels to collect views from full-time Hong Kong workers who have had WFH experience during the coronavirus outbreak. A total of 1,976 effective responses were collected for the data analysis.FindingsThe findings of this study indicate that WFH effectiveness is improved by personal and family well-being but reduced by environmental and resource constraints. When workers are experiencing higher WFH effectiveness, they have a higher preference for WFH even after the pandemic; the female workers preferred WFH twice per week, while the male workers more often preferred WFH once per week. Finally, workers from the management and the self-employed levels demonstrated a lower preference for WFH, compared to the front-line and middle-grade workers.Originality/valueThis paper fulfils to provide a timely reflection on workers' post-pandemic WFH preference, the factors affecting their WFH effectiveness and the demographic differences inducing to the differentiated preferences.
The association between corporate governance mechanisms and compliance with IFRS mandatory disclosure requirements: evidence from 12 African countries
Authors: Mnif Yosra , Borgi Hela 
Published: October 2020

PurposeThe purpose of this study is to examine the association between two corporate governance (CG) mechanisms, namely, the board of directors and the audit committee (AC) and the compliance level with International Financial Reporting Standards (IFRS) mandatory disclosure requirements across 12 African countries.Design/methodology/approachThis paper uses a self-constructed checklist of 140 items to measure the compliance with IFRS mandatory disclosure requirements (here after, COMP) of 202 non-financial listed firms during the 2012–2016 period. This paper applies panel regressions.FindingsThe findings reveal that CG mechanisms play an important role in enhancing compliance with IFRS in the African context. The results show that board independence, AC independence and the number of meetings held by the AC are positively associated with COMP. Regarding expertize, this paper find that AC industry expertise along with accounting financial expertise is associated with a higher level of COMP than accounting financial expertize alone. These results show the importance of the CG mechanisms to enforce African companies to fully comply with IFRS required disclosures.Practical implicationsThe findings should give a signal to supervisory authorities that more effort is necessary to enforce IFRS across African countries if the introduction of IFRS is to bring the expected benefits to investors and other users. Hence, the lack of full compliance should remain a concern for regulators, professional accounting bodies and policymakers.Originality/valueThis study contributes to the literature by providing further insights that, within the African region an understudied context, extend current understanding of the association between CG mechanisms and COMP.
Multiculturalism in Singapore and Malaysia: approaches and outcomes
Authors: Kuah Adrian T.H. , Kim Chang H. , Le Queux Stéphane 
Published: October 2020

PurposeThis paper examines cases of multiculturalism in Singapore and Malaysia. Through causal sociocultural mechanisms, the authors observe how two countries in proximity, with shared histories and demographic profiles, achieve differing outcomes in regard to social cohesion and competitiveness.Design/methodology/approachThe paper employs case-centric process tracing (CPT) to build a “plausible” explanation of causal mechanisms that can contribute to social cohesion and competitiveness. The authors adopt a common analytical framework to distil the nuances of generalizability and a cross-case analysis in order to ascertain factors that enable multiculturalism.FindingsDifferent causal mechanisms result in diverging outcomes in the two countries. In managing multiculturalism, Singapore has pursued policy actions emphasizing “integration and pragmatism,” while Malaysia has followed a model of “separation and preferentialism.” Judging by a selected number of established indicators, Singapore's multiculturalism outcomes seem more successful than that of Malaysia in respect to areas of national competitiveness and interethnic tolerance.Practical implicationsThis paper sheds insights on the policy actions that promoted multicultural integration. The process tracing approach is found to be a useful tool in helping policymakers understand how intrinsic mechanisms can contribute to more/less desirable socioeconomic outcomes.Originality/valueTogether with the evidence using the CPT approach, the paper draws attention to multiculturalism evolving through distinctive sets of public policy. The authors ultimately suggest that such policies can be paralleled to the function played by institutions in leading to “varieties of capitalism” and have an impact on achieving cohesive and competitive societies.
Inferred respect: a critical ingredient in customer satisfaction
Authors: Ashworth Laurence , Bourassa Maureen A. 
Published: October 2020

Purpose
This paper aims to address the following question: Do consumer inferences of respect (disrespect) contribute to satisfaction (dissatisfaction)? The research question is explored over two studies. The first aimed to test whether respect spontaneously emerged as an important component of consumer satisfaction. The second aimed to examine whether perceptions of respect could explain consumers’ satisfaction response beyond traditional antecedents of satisfaction (i.e. product and service factors, expectations).

Design/methodology/approach
The first (pilot) study examined whether respect/disrespect spontaneously emerged in written descriptions of highly satisfactory/dissatisfactory experiences (n = 356). The second (main) study used a survey methodology to test whether perceptions of respect could explain customer satisfaction beyond traditional antecedents (n = 2,641 plus n = 398).

Findings
Drawing on theories from social psychology and organizational justice, the current study argues that perceived respect, as inferred by customers from elements of their interactions with organizations, may also be critically involved in the satisfaction response.

Research limitations/implications
Conceptually, the findings place respect as a central antecedent among satisfaction determinants.

Practical implications
Practically, this research underscores the importance of enacting respect and avoiding actions that communicate disrespect because of their effect on satisfaction.

Originality/value
Customer satisfaction is critically important to organizations and so a great deal of research or work has sought to understand its causes – traditionally product performance, service quality and expectations. This current work, or This current research argues that inferred respect, as an indicator of the extent to which people perceive they are valued, should have an important, and general, influence on satisfaction that goes beyond what traditional determinants of satisfaction can explain.
Subsidiarity as secret of success: “Hidden Champion” SMEs and subsidiarity as winning HRM configuration in interdisciplinary case studies
Authors: Mear Fred , Werner Richard A. 
Published: October 2020

PurposeThis paper contributes to the theory of the relationship between human resource management (HRM) and innovation at small- to medium-sized enterprises (SMEs) by conducting a conceptual analysis of the question why Germany boasts by far the highest number of “Hidden Champion” SMEs. This is done by case studies from the army and public financial management of aid disbursal in developing countries. Implications for HRM at SMEs are discussed.Design/methodology/approachConceptual analysis using case studies.FindingsContributing towards filling the gap concerning theoretical underpinnings of the link between HRM and innovation, we suggest that interdisciplinary work from relevant organisational case studies indicates that the concept of institutional design to provide motivational incentives may be relevant, especially concerning high performance systems with bundles of HRM practices. Specifically, the fundamental principle of subsidiarity is found to be important.Research limitations/implicationsThe research is broadly applicable to organisations of all kinds, as the diverse case studies indicate. We point towards tentative implications for the firms that account for the majority of the work force, namely SMEs, and among them the most successful ones, the so-called “Hidden Champions”.Practical implicationsHR managers can improve motivation, performance and innovation by decentralising decision-making as far as possible, while ensuring the overall organisational goals are well understood and shared, and resources are dedicated to train and educate staff. Additionally, the conception of rank-order competitions complements the institutional design.Social implicationsGreater productivity and material performance as well as greater job satisfaction via larger autonomy and decision-making power on the local level can be achieved by the application of subsidiarity as key HRM configuration. This can be employed at SMEs, as discussed, but also other organisations. Further, the principle of subsidiarity and the greater emphasis on staff training and education may help reduce inequality.Originality/valueOur paper contributes towards filling the gap in the literature on the link between HRM and innovation, by identifying the role of subsidiarity. We introduce an interdisciplinary perspective, with contributions from economics and psychology, among others. We also contribute to the history of HRM.
Study on the joint mechanical properties of steel structure buildings
Authors: Chen Jiaqiang 
Published: October 2020

PurposeThe main supporting frame of steel structure buildings is steel, and the beam-column joints of the steel structure directly affect the stability and strength of the supporting frame.Design/methodology/approachThis paper briefly introduced the beam-column joints which are used for ensuring the stability of buildings in the steel structure building, selected the fabricated beam-column joints which were different from the traditional welding methods, tested the fabricated beam-column joints with the reaction frame and jack and detected the influence of the thickness and length of the splice plate on the mechanical properties of joints.FindingsThe results showed that the joint stress and the displacement in the vertical direction increased under greater load no matter which kind of fabricated joint was used; under the same load, the thickness and length of the splice significantly affected the mechanical properties of joints, and the larger the thickness and length, the smaller the joint stress and displacement in the vertical direction.Originality/valueTo sum up, increasing the thickness or length of the splice plate of the fabricated joint can effectively improve the mechanical properties of joints.
Cognitive dysfunction in older prisoners in Germany: a cross-sectional pilot study
Authors: Verhülsdonk Sandra , Folkerts Ann-Kristin , Höft Barbara , Supprian Tillmann , Kessler Josef , Kalbe Elke 
Published: October 2020

Purpose
The purpose of this study is to collect the first empirical data on the cognitive state of elderly prisoners in Germany and to examine associations between cognitive function and sociodemographic, clinical and incarceration characteristics.

Design/methodology/approach
All prisoners aged 60 years and older of five prisons in North Rhine-Westphalia, Germany, were asked to participate. The cognitive screening instruments mini-mental state examination (MMSE) and the DemTect were used to assess global cognition. Executive functions were tested with the trail making test and the frontal-assessment-battery. The Patient Health Questionnaire (PHQ-9) was used to assess participants’ affective state.

Findings
The sample of this study consisted of 58 prisoners with a mean age of 65.52 years (standard deviation = 6.03); 82.8% are male. Using the MMSE with age- and education-corrected z-scores, 36.9% of the prisoners showed marginal or impaired global cognition scores. Using the DemTect, 41.4% of the prisoners were classified as being cognitively impaired. Up to 40% of the prisoners showed deficits in executive functioning and around 60% of the prisoners showed depressive symptoms. The correlation analysis revealed significant associations between cognitive scores and age (rho = –0.335, p = 0.014), education (rho = 0.309, p = 0.020), sentence duration (rho = 0.409, p = 0.007) and duration of current incarceration (rho = 0.302, p = 0.043). The DemTect total score was significantly associated with the PHQ-9 (rho = –0.335, p = 0.016).

Practical implications
A large group of the prisoners showed a higher prevalence of cognitive dysfunction than that observed in same-age people who are not incarcerated. Taken together, there is an urgent need for an adequate management of older cognitively impaired prisoners including routine cognitive testing and guidelines-oriented treatment of cognitive symptoms.

Originality/value
This study has several strengths. To the best of the authors’ knowledge, this is the first study examining the cognitive and affective state in a German prison population. The authors considered female and male prisoners, as well as different prison settings, representing a realistic prison sample. The authors used several neuropsychological instruments to get a more detailed insight into the older prisoners’ cognitive status while trying to consider the economy of time and possible attention deficits to prevent dropouts during testing.
The effects of anchoring on backers' pledge in reward-based crowdfunding: evidence from Taiwanese market
Authors: Kuo Ying-Feng , Lin Cheng-Han , Hou Jian-Ren 
Published: October 2020

PurposeCrowdfunding allows enterprises or individuals to collect funds from numerous other individuals. This study applies the anchoring effect and range theory in reward-based crowdfunding to explore how different pledge option designs affect the backers' final pledge amount. Moreover, this study examines whether showing the current average amount pledged in the fundraising process has an anchoring effect on the subsequent backers' pledge amount.Design/methodology/approachOnline experiments were conducted, and data were analyzed using the Kruskal–Wallis test and Spearman rank correlation analysis.FindingsResults show that among the three pledge option designs, employing the “bolstering range offer” has the highest backing amount. However, presenting the current average amount pledged in the fundraising process has a reversed anchoring effect on subsequent backers' pledge amount only in the case of a crowdfunding project in the physical goods category with a “point offer.”Originality/valueTo the best of authors’ knowledge, no reward-based crowdfunding platform has yet provided the pledge option design of a “bolstering range offer.” This study reveals that the “bolstering range offer” can significantly increase the amount pledged. This study extends the crowdfunding research area to crowdfunding success and suggests a novel way to set up pledges.
Strategic agility and the effects of firm age and environmental turbulence
Authors: Reed Jonathan H. 
Published: October 2020

PurposeThe purpose of this empirical paper is to operationalize the Doz and Kosonen (2010) model of strategic agility, consisting of three dimensions and 15 subfactors and to test its relationship with firm performance under multiple contingencies.Design/methodology/approachA CEO-level survey is conducted to collect a sample of 73 firms from three industries in the US state of Florida. Factor analysis and convergence with similar criterion are used to validate the strategic agility construct. Multiple regression is used to test hypothesized relationships.FindingsThe findings support construct validity of Doz and Kosonen's model. Moreover, firm age and environmental turbulence are found to be important contingency factors. Environmental turbulence is found to moderate the relationship between firm age and strategic agility. Firm age and environmental turbulence are found to jointly moderate the relationship between strategic agility and firm performance.Research limitations/implicationsIt is evident that firms may benefit from strategic agility depending on their age and environment. The results encourage future longitudinal research addressing causality.Originality/valueThe paper contributes to research by validating a more comprehensive model of strategic agility and identifying contingency factors that help to explain prior mixed results on the relationship between strategic agility and performance.
A theory of information overload applied to perfectly efficient financial markets
Authors: Pernagallo Giuseppe , Torrisi Benedetto 
Published: October 2020

PurposeIn the era of big data investors deal every day with a huge flow of information. Given a model populated by economic agents with limited computational capacity, the paper shows how “too much” information could cause financial markets to depart from the assumption of informational efficiency. The purpose of the paper is to show that as information increases, at some point the efficient market hypothesis ceases to be true. In general, the hypothesis cannot be maintained if the use of the maximum amount of information is not optimal for investors.Design/methodology/approachThe authors use a model of cognitive heterogeneity to show the inadequacy of the notion of market efficiency in the modern society of big data.FindingsTheorem 1 proves that as information grows, agents' processing capacities do not, so at some point there will be an amount of information that no one can fully use. The introduction of computer-based processing techniques can restore efficiency, however, also machines are bounded. This means that as the amount of information increases, even in the presence of non-human techniques, at some point it will no longer be possible to process further information.Practical implicationsThis paper explains why investors very often prefer heuristics to complex strategies.Originality/valueThis is, to the authors’ knowledge, the first model that uses information overload to prove informational inefficiency. This paper links big data to informational efficiency, whereas Theorem 1 proves that the old notion of efficiency is not well-founded because it relies on unlimited processing capacities of economic agents.
The effect of family history of hypertension and polymorphism of the ACE gene (rs1799752) on cardiac autonomic modulation in adolescents
Authors: Dias‐Filho Carlos Alberto Alves , Soares Nivaldo de Jesus Silva , Bomfim Maria Rosa Quaresma , José Dias Carlos , Vidal Flavia Castello Branco , Magalhães Bruna Cruz , Ferreira Andressa Coelho , Monteiro Sally Cristina Moutinho , Salvador Emanuel Péricles , de Barros Carlos Castilho , Correia Poliana Espíndola , Rodrigues Bruno , Mostarda Cristiano Teixeira 
Published: October 2020

AbstractThis study aims to analyze the behaviour of cardiac autonomic modulation in adolescents with a family history of hypertension along with polymorphism of the ACE gene (rs1799752). The study involved 141 adolescents, with a mean age of 14.89, divided into the following six groups: offspring of normotensive parents (ONP): DD, DI and II; and offspring of hypertensive parents (OHP): DD, DI and II. Blood pressure, body composition, family history of hypertension, sleep disorder, and sexual maturation were assessed for the groups' characterization. Afterwards, an electrocardiogram was performed, and oral mucosal cells were collected to analyze heart rate variability and genotypic research of angiotensin‐converting enzyme. The main finding of this study was the decrease of vagal action in group OHP (genotype DD) relative to group ONP (genotype II): LF (%), 54.25 ± 3.14 vs 39.33 ± 3.80; HF (%), 45.74 ± 3.14 vs 60.66 ± 3.80; LF/HF, 1.48 ± 0.23 vs 0.68 ± 0.19. The results also showed changes in the variable diastolic blood pressure (DBP) in OHP (genotype DI) to ONP (genotype II) groups: 72.99 ± 2.33 vs 63.27 ± 1.72; and OHP (genotype DI) to ONP (genotype DD) groups. Adolescents with genotype DD and a family history of arterial hypertension present chances in cardiac autonomic modulation, the cardiac parasympathetic modulation is lower in these adolescents in comparison to participants of ONP + II group.