bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of aqueous extract of Colocasia esculenta against high-fat diet-induced non-alcoholic fatty liver disease in rats
Authors: Kanala Somasekhar Reddy  , Akkiraju Sudheer  , PamisettyLikitha  Sree  , Bhupalam Pradeepkumar  , Dharmavaram Deepthi  , Chinthaginjala Haranath  
Published: October 2020

Non-alcoholic fatty liver disease (NAFLD) is becoming a major public health problem due to the increasing incidence of obesity and diabetes in India for the last two decades. The present work is aimed to investigate the effect of aqueous extract of Colocasia esculenta against (AECE) high-fat diet-induced non-alcoholic fatty liver disease in Wistar albino rats. Wistar albino rats were assigned in to four groups as follows; Group I: Normal conventional diet, Group II: High fat diet, Group III & Group IV: Combined high fat diet and different doses of Colocasia esculenta (200 and 400 mg/kg, p.o) for 4 weeks.Treatment with aqueous extract of Colocasia esculenta(200mg/kg, 400mg/kg bw) significantly reduced the body weight and weight gain. In addition, it also significantly reduced the serum triglycerides, total cholesterol, LDL cholesterol, VLDL cholesterol and showed a significant increase in HDL cholesterol as well as significant improvement in liver cholesterol and triglyceride content. AECE treated rats exhibited a significant beneficial effects on levels of liver function markers and oxidative stress and also reversed the histopathological changes.The study suggested the therapeutic potential of AECE against NAFLD, acting in part through anti-obesity, antioxidant mechanisms, and liver marker enzymes.
Sub-Acute Toxicity Study of a Type-I Pyrethroid Permethrin on Testis of Mus Musculus
Authors: Zeba Siddiqui  , Ketaki Desai  
Published: October 2020

Pesticide usage has witnessed a rise in the current years to overcome the glitches of food scarcity because of incessant increase in population. Regardless of its extensive use in agriculture and related fields, these should be properly and thoroughly investigated because of unexplored danger which they bring along. The present investigation deals about the effects of one such pesticide, Permethrin, belonging to the class of synthetic pyrethroids, having broad range application in the field of agriculture, as an insect repellent, in lice shampoos, in the treatment of scabies and numerous other commercial uses. Although few reports have documented its adverse effect on the vital organs in different experimental models, there still persist lacunae in literature about its effect on the male reproductive tissue. Hence, the present study was aimed to evaluate the effects of Permethrin on the male reproductive gonad of Swiss albino mice. Permethrin (130 mg/kg body weight) was administered orally for a period of 21 days after which the biochemical parameters in testis were assayed. The results showed that Permethrin administration lowered the gravimetric indices (body weight p<0.002, organ weight p<0.001) and decreased the levels of protein (p<0.001) and cholesterol (p<0.001), which is an important precursor in the formation of androgens. Essential enzymes like 3β and 17β hydroxysteroid dehydrogenase which are pivotal in the steroidogenesis pathway were also found to be depleted (p<0.001 and p<0.002 respectively). These findings were further confirmed by the histopathological analysis and indicated that Permethrin had negative effects on the male reproductive system and can be one of the contributing factors leading to infertility.
Estimation of Dapagliflozin in Pure and Marketed Formulation by Validated Reverse Phase-High Performance Liquid Chromatographic Method
Authors: V.Navya Sree  , Dr.K. Bhavyasri  , Dr.M.Sumakanth  , R.Swethasri  
Published: October 2020

Dapagliflozin is a highly selective, orally active and reversible inhibitor of the human sodium glucose co- transporter 2 (SGLT2). The dapagliflozin is a diabetic drug which is used with proper diet and exercise in adults with type 2 diabetes to improve the glycemic control. The aim of this study is to develop a rapid, precise and accurate RP- HPLC method for estimation of dapagliflozin in bulk and formulation as per ICH guidelines. The chromatography was carried on Sunsil C18 (150 X4.5mm, 5µ) column HPLC (Water’s) using a mixture of methanol and water at different ratios and finally optimized with 85:15 v/v as mobile phase with flow rate 1.0ml/min at 225nm. The correlation regression is found to be 0.999. The retention time was found to be 2.74min. The accuracy of the present method was evaluated at 50%, 100% and 150%. The recoveries of dapagliflozin API and tablet were found to be in the range of 98.5% - 100.6%. Precision studies were carried out and the relative standard deviation values were less than two. The method was found to be robust. The limit of detection and limit of quantification were determined as 0.011µg/ml and 0.034µg/ml. The proposed method was found to be rapid, precise, accurate and robust and can be used for the estimation of dapagliflozin in API and Pharmaceutical dosage form.
Technological Development and The Dynamics of Juwana’s Fisherman Social Structure
Authors: Situmeang Widya Hasian , A Kinseng Rilus , P Lubis Djuara 
Published: October 2020

Changes created by technological developments are not only about material changes, but are also closely related to changes in social structure in the community as users and consequences recipients of these technologies application. The capture fisheries community is one of many communities that have also experienced the development of fishing technology. It cannot be denied that technological sophistication is driving the production of the fishing community. However, this increase is not necessarily followed by an increase in welfare for the community. This paper aims to examine technological developments and changes in social structure in the fishing community in Juwana, especially in Bendar Village and Bajomulyo Village, and identify their implications for community welfare. The research that underlies this paper is conducted using qualitative methods. The results showed that the development of technology brought changes in social structure in the fishing community. The economy and welfare of the community are getting better due to the efficiency of fishing with the latest technology. Solidarity that grows in the fishing communities in the two villages, is a key factor in preventing inter-class exploitation by maintaining the position of members of the upper stratification of fisher community from competition with upper strata outside the community, as well as providing a space for community members from the middle and lower strata to carry out social upward mobility. Keywords: fisher, fishing technology, social structure, solidarity, social mobility.
An Employer Perspective: Employment Relations During and Beyond the 2017-2020 General Election
Authors: Mackay Paul 
Published: October 2020

The present government has presided over a number of changes to employment law and has committed to more, should it be returned to office in this year’s general election. However, Covid-19 has cast a debilitating shadow over employment relations, in general, and is obscuring the effects of recent changes, at least for now. It is, therefore, harder to comment on whether or not the changes made, to date, have helped or hindered. However, it is possible to look forward at some of the additional changes being proposed, and assess whether or not, particularly in the economic confines of the Covid-19 straitjacket, changes to holidays, pay equity, and collective bargaining will assist New Zealand’s return to prosperity. This article examines some of these issues through an employer lens.
PENYUSUNAN PETA GEOGRAFISBERBASIS TATA RUANG DAN PEMANFAATAN WILAYAH DESA CINTARATU UNTUK OPTIMALISASI PERKEMBANGAN WILAYAH
Authors: Andhikawati Aulia 
Published: October 2020

Desa Cintaratu memiliki luas lahan 1.029 Ha dengan pembagian lahan sebagai tempat pendidikan, pertokoan, lahan wisata dan lahan pertanian serta pemukiman. Optimalisasi pemanfaatan lahan harus diatur melalui perencanaan tata ruang yang disesuaikan dengan kondisi wilayah setempat agar tidak terjadi penyalahgunaan lahan di setiap Dusun. Berdasarkan hal tersebut maka perlu dilakukan penyusunan peta geografis berbasis tata ruang dan pemanfaatan wilayah Desa Cintaratu untuk optimalisasi perkembangan wilayah. Tujuan penelitian ini, yaitu untuk memetakan kondisi tata ruang dan pemanfaatannya berbasis potensi sumber daya alam dan mengidentifikasi potensi wilayah Desa Cintaratu. Metode yang digunakan yaitu wawancara mendalam kepada pejabat pemerintah terkait, BAPPEDA dan masyarakat desa Cintaratu, observasi lokasi/kawasan yang akan dikaji, serta mengkaji dan menganalisis data, dokumen, arsip dan lainnya yang berkaitan dengan pengembangan Desa Cintaratu. Hasil yang diperoleh yaitu: 1) Dusun Bontos memiliki potensi sebagai lini dagang dan lini pertanian dengan luas 80% dari total Sawah di Desa, 2) Dusun Cintasari memiliki potensi sebagai pusat dagang, 3) Dusun Sukamanah memiliki potensi sebagai pusat pendidikan, tempat usaha, pemukiman dan perkantoran, 4) Dusun Panglanjan sebagai tempat wisata alam dan perdagangan, dan 5) Dusun Gunung Tiga sebagai tempat pariwisata, yaitu wisata alam Jojogan dan pusat perdagangan. Berdasarkan hasil tersebut dapat disimpulkan bahwa pemanfaatan tata ruang dan wilayah Desa Cintaratu terdiri dari wilayah pertanian di Dusun Bontos, pemukiman di Dusun Sukamanah, pendidikan di Dusun Sukamanah, pariwisata di Dusun Gunung Tiga dan perdagangan yang tersebar di setiap Dusun.
Alchemical Cities, Apocalyptic Cities: The City as an Exponent of Magical Realism and Ideology in Angela Carter’s Novels
Authors: Muždeka Nina 
Published: October 2020

Abstract
Reality in Angela Carter’s magical realist novels is depicted through the deployment of numerous picturesque details that correspond to the readers’ experiential reality, differentiating such a world from non-realist forms. Though the magical realist fictional world is akin to the one outside of the fictional reality, the mode’s strategy still differs from that of traditional realism due to the absence of a purely mimetic role. Initially serving to establish what Roland Barthes termed l’effet de reel (the effect of reality), the city in Carter’s novels is indeed constructed according to the principles of magical realism and creates plausible links between textual and extratextual realities. Further inclusion of magical, uncanny elements into such a world, in one respect, leads to the creation of excentric spaces that promote the position of the marginalized Other and allow alternative outlooks on life to gain prominence. A hybrid reality that is the ultimate result of the coexistence of the normal and the uncanny leads to the subversion of what Carter saw as patriarchal stereotypes, primarily due to the fact that it problematizes and ultimately negates their very foundation. In other words, if we cannot agree on the criteria for what is real, how can we trust the ultimate authority of any other criteria? The city in Carter’s novels thus acts as a suitable literary venue for revealing the author’s ideological position.
From Outcasts in the Streets to Movers on the Hill: Narrating the Dark Side of Washington, D.C. in D.C. Noir
Authors: Andreescu Raluca 
Published: October 2020

Abstract
This article examines the manner in which the recent collection D.C. Noir sets out to illuminate the dark urban corners of the so-called “Capital of the World.” I will look at how the neighborhood-based short stories in this collection reveal the urban underbelly of the American nation’s capital, its seedy underworld, the dark side of domestic life and murkiness of family ties, the racialized practices and institutionalized corruption plaguing the great American city. I argue that, through the collective voices of its residents, these stories offer precious insights into life as lived in the various corners of Washington, D.C., and bring to the fore a world populated not only by outcasts and the disenfranchised, but also by law enforcement officers, politicians, and high-profile representatives, similarly acting under the constraints of a dysfunctional city.
Assessment of oral mucositis degree due to cytostatic treatment in patients with malignant lymphomas
Authors: Muica Adrian , Berneanu Florentin-Daniel , Hănțoiu Liana , Kinga Dorner , Crăciun Adriana-Elena 
Published: October 2020

Abstract
Introduction: Oral mucositis characterized by inflammation of the oral mucosa, ulcers, angular cheilitis, accompanied by pain in the maxillary facial area are symptoms of patients who have undergone cytostatic treatment, affecting over 75% of high-risk patients.
Material and methods: From the total of 182 patients with hematological malignancies, we selected 59 patients, diagnosed with malignant lymphomas and treated at the Hematology Department of the Medical Clinic 1 in Tîrgu Mureș, between July 2013 and June 2016, analyzing the data in the data observation sheets. The study is a retrospective one.
Results: In the group of patients studied, who were treated based on the aforementioned cytostatic plans, we found that the CVP + Rituximab plan frequently causes 1st and 2nd class stomatitis, with no patients with 3rd and 4th class stomatitis. The CHOP + Rituximab therapy plan in a total of 80 applications had complications of 1st and 2nd class stomatitis, much more frequent 1st class without stomatitis of 2nd and 4th degree. Grade III stomatitis occurs in two cases in the CHOP-Bleo belts. Introducing dental medicine in the context of medical multidisciplinarity in oncology hematology is a real necessity because the oral complications of chemotherapy treatments by their severity can lead to compromise of the treatment protocol by reducing the doses or even stopping the treatment
Conclusions: Malignant hemopathies represent a significant percentage in dental disorders, and among them, the maximum severity belongs to the non-Hodgkin and Hodgkin malignant lymphomas. Stomatitis, also called gingivotoxic stomatitis caused by medication, is an acute oral complication, with erythema and edema of the entire oral cavity. The role of the dentist in the diagnosis, prevention and treatment of oral lesions, following the cytostatic therapy, is extremely important.
Taking dental impressions of dental medicine students: with and without vomiting reflex
Authors: Cristina Molnar-Varlam , Melinda Szekely , Sîrbu Tudor , Iunia-Beatrice Moldovan 
Published: October 2020

Abstract
Introduction: It is a well-known fact that during a dental impression, some patients suffer from the gag reflexes. Aim of the study: Even if the main tendency is to use medication, our goal is to find a way to combat it.
Material and methods: With the help of our 155 volunteering students, from UMFST Târgu Mureș, who agreed on having their dental impression taken, using alginate material, we tried to combat the gag reflex, using the following techniques: the high-leg method, salt crystals, as well as using a special impression tray.
Results: When we applied all of these methods, great attention was payed, as we diligently wrote everything down. After all the work was done, we obtained the following results: 130 did not show any vomiting signs, 17 of them presented moderate vomiting reflex and only 8 of them have shown extreme vomiting reflex, leading to the point where the impression could not be performed.
Conclusions: On the one hand, for the less informed people, these techniques present a better outcome; on the other hand, however, we wish to highlight one thing: the skills of the doctor are of utmost importance.
The importance of implant-supported overdentures in a bimaxillary complete edentulous patient – case report
Authors: Melchner Valentin , Bechir Edwin Sever , Berneanu Florentin Daniel 
Published: October 2020

Abstract
Introduction. Complete edentulism is escorted by various comorbidities, which affect an individual. The management of edentulous patients was approached since the early days of dentistry.
The aim of this case report was to present the implanto-prosthetic rehabilitation of a bimaxillary complete edentulous patient with implant-supported overdentures, by using Straumann dental implants.
Case presentation. This case report presents the applied treatment to a bimaxillary complete edentulous patient, where the predictable osseointegration and implant stability after the placement of implants was possible, with the purpose to support the overdentures.
Conclusions. The oral rehabilitation of complete bimaxillary edentulism through implant-supported overdentures is a procedure with a predictive treatment that presents beneficial aspects in the quality of life of the patients.
Examination of Honeycomb Core Compliance in Sandwich Structure
Authors: Nowakowski Dominik , Baran Marta , Lisiecki Janusz , Kłysz Sylwester , Synaszko Piotr 
Published: October 2020

Abstract
The objective of the research presented in this paper was to determine the honeycomb core compliance of a sandwich structure of the horizontal stabilizer of the MiG-29 fighter jet in the static compression test. The study of the specimen was conducted based on the ASTM C365/C365M standard. The article presents the results of experimentally determined dependencies and strength parameters, i.e. the force-displacement dependence, the compressive modulus and the honeycomb core deformations.
Impact Loads and Crash Safety of the Cockpit of a Composite Glider
Authors: Lindstedt Łukasz , Rodzewicz Mirosław , Rzymkowski Cezary , Kędzior Krzysztof 
Published: October 2020

Abstract
One major problem associated with gliding is the safety of the crew during landings in the country outside the airfield. The analysis of glider-accident statistics shows that such out-landings may significantly influence the safety. Therefore, of vital importance are the crashworthiness properties of the glider fuselage structure. The subject of the study was the PW-5 glider fuselage made of composites and subjected to high loads typical of glider crashes. The aim was to provide experimental data for validation of a numerical model of the cockpit-pilot system during impact. Two experimental tests with the composite glider cockpit were performed using a typical car-crash track. During the first test the cockpit with a dummy inside was crashed onto the ground at the angle of 45 degrees at a speed of 55 km/h. Accelerations and deformations at chosen points in the cockpit as well as signals coming from the dummy sensors and forces in the seat belts were recorded. The second test was an impact into a concrete wall at a speed of about 80 km/h. The full-scale tests were accompanied by a number of quasi-static and dynamic laboratory tests on samples of composite material. The experimental tests provided valuable results for the parametrical identification of a simulation model developed using the MADYMO software.
Financial Stability and Climate Change
Authors: Fabris Nikola 
Published: October 2020

Abstract
Fighting climate change is one of the biggest challenges in the 21st century. Climate change that leads to global warming has been increasingly visible in our environment. Extreme weather conditions such as hurricanes, floods, and droughts have been escalating and their acceleration can be expected in the future. They cause changes in sea levels, epidemics, large fires, etc. Increasingly, we are witnessing minor or major damage caused by these extreme weather conditions. Numerous studies have proven that climate change has negative impact on economic growth and prosperity. However, this paper starts from the premise that in addition to unequivocally identified threats, climate change also creates opportunities.
The paper reaches a conclusion that climate change can adversely affect balance sheets of financial institutions. Therefore, climate change is a source of financial risk and thus a part of the mandate of central banks and supervisors in preserving financial stability. This type of risk has not been given enough attention by either supervisors or financial institutions over the past period. This paper develops a model for managing financial risks as a result of climate change.
Testing for the Effectiveness of Inflation Targeting in India: A Factor Augmented Vector Autoregression (FAVAR) Approach
Authors: Jithin P , Suresh Babu M 
Published: October 2020

Abstract
Employing Factor Augmented Vector Autoregression (FAVAR) model where factors are obtained using the principal component analysis (PCA) and the parameters of the model are estimated using Vector Autoregression framework, we analyse how changes in monetary policy variables impact inflation, output, money supply, and the financial sector in India. Our results for the period 2001:04 to 2016:03 show that the benchmark FAVAR model showed more reliable results than baseline VAR model. Benchmark FAVAR model shows the existence of weak ‘liquidity puzzle’ in India. The impulse responses from the FAVAR approach reveal that monetary policy is more efficient in explaining the variations in inflation rather than stimulating output indicating its effectiveness in attaining the objective of price stability.
Working with a Student Exhibiting School Difficulties. Teachers Auto-reflection
Authors: Kadłubowska Sandra 
Published: October 2020

Summary
The article shows the benefits of educational projects at the stage of early school education: „I work with ozobots – I program perfectly”. The aim of the course was to introduce programming elements into classes using ozobots – educational robots. Research was carried out in order to help the students overcome developmental difficulties. The evaluation of the project proves that the additional activities that were carried out enhanced the motivation to learn, fostered children’s curiosity, improved the self-esteem of students with educational difficulties and, as a consequence, reduced the risk of anxiety disorders and child phobia at the stage of early school education.
The Civic Engagement of University Students as a Protective Factor in Terms of the Resilience Concept
Authors: Marciniak Mateusz 
Published: October 2020

Summary
The paper analyses the relationship between the civic engagement and risk behaviours of young people from the perspective of resilience mechanisms. The resilience concept focuses on social and individual features which protect (give the resistance) against risk factors appearing in adverse living conditions. Civic engagement is included among potential protective factors. Can this engagement can be considered as a protective factor in the context of the crisis of democracy and social capital erosion, and if so, to what extent? The goal of this paper is to analyze the civic engagement of university students as a potential protective factor against risk behaviours, in particular, alcohol abuse. Firstly, the basic assumptions of resilience and civic engagement (in social capital perspective) are defined. The second section is based on selected findings from the study Studenci 2019’ (N=4503): the associations between the degree of civic engagement of university students and alcohol-related problems. The research results show that the students from the group with a higher level of civic engagement (in comparison to those with a lack or low level) are found significantly more often among students with problems related to risk-drinking and alcohol abuse. The article ends with an explanation of thoe findings which may be considered surprising in light of the concept of resilience.