bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and Socio-Demographic Correlates of Poor Mental Health Among Older Adults in Agricultural Areas of China
Authors: Jin Yu , Zhang Yun-Shu , Zhang Qinge , Rao Wen-Wang , Zhang Li-Li , Cui Li-Jun , Li Jian-Feng , Li Lin , Ungvari Gabor S. , Jackson Todd , Li Ke-Qing , Xiang Yu-Tao 
Published: November 2020

Objective: Poor mental health is associated with impaired social functioning, lower quality of life, and increased risk of suicide and mortality. This study examined the prevalence of poor general mental health among older adults (aged 65 years and above) and its sociodemographic correlates in Hebei province, which is a predominantly agricultural area of China.Methods: This epidemiological survey was conducted from April to August 2016. General mental health status was assessed using the 12-item General Health Questionnaire (GHQ-12).Results: A total of 3,911 participants were included. The prevalence of poor mental health (defined as GHQ-12 total score ≥ 4) was 9.31% [95% confidence interval (CI): 8.4–10.2%]. Multivariable logistic regression analyses found that female gender [P &lt; 0.001, odds ratio (OR) = 1.63, 95% CI: 1.29–2.07], lower education level (P = 0.048, OR = 1.33, 95% CI: 1.00–1.75), lower annual household income (P = 0.005, OR = 1.72, 95% CI: 1.17–2.51), presence of major medical conditions (P &lt; 0.001, OR = 2.95, 95% CI: 2.19–3.96) and family history of psychiatric disorders (P &lt; 0.001, OR = 3.53, 95% CI: 2.02–6.17) were significantly associated with poor mental health.Conclusion: The prevalence of poor mental health among older adults in a predominantly agricultural area was lower than findings from many other countries and areas in China. However, continued surveillance of mental health status among older adults in China is still needed.
HUBUNGAN KEPUASAN TERAPI DENGAN KUALITAS HIDUP PASIEN DIABETES MELLITUS TIPE-2 DI PELAYANAN PRIMER (PUSKESMAS JETIS 1 BANTUL)
Authors: Akrom  , Muhammad Muhlis  , Yenny Sri Wahyuni  
Published: November 2020

Diabetes adalah penyakit kronis serius yang terjadi karena pankreas tidak menghasilkan cukup insulin (hormon yang mengatur gula darah atau glukosa), atau ketika tubuh tidak dapat secara efektif menggunakan insulin yang dihasilkannya. Melitus merupakan sindrom metabolis kronis yang menjadi salah satu penyebab kematian terbesar di dunia. Desain Penelitian ini adalah penelitian jenis Observasional, dengan menggunakan pendekatan cross sectional, dimana subyek penelitian hanya diobservasi. Penelitian ini mengambil subyek sebanyak 109 pasien. Pengambilan data secara prosepektif dan dilakukan dengan cara mengumpulkan informasi dari pasien melalui wawancara tatap muka (face-to-face interview) menggunakan kuesioner. Kuesioner yang digunakan pada penelitian ini berjumlah dua kuesioner yaitu, data demografi pasien, kuesioner kepuasan (TSQM), kuesioner Kualitas Hidup (EQ5D).
Analisis data menggunakan Uji Statistik dengan bantuan SPSS versi 23. Data sosio-demografi pasien meliputi jenis kelamin, usia, pernikahan, pekerjaan, pendidikan dan penyakit penyerta pasien pendeita DM type 2 disajiakan dalam tabel distribusi frekuensi. Uji Chi Squaredilakukan untuk mengetahui hubungan antara sosio-demografi dengan kepuasan terapi dan hubungan sosio-demografi dengan kualitas hidup.
Hasil hitung dengan bantuan SPSS versi 23 menunjukkan bahwa nilai p value >0,05 sehingga dapat disimpulkan bahwa tidak ada hubungan antara sosio-demografi dengan kepuasan terapi dan tidak ada hubungan antara sosio-demografi dengan kualitas hidup. Hubungan antara kepuasan terapi dengan kualitas hidup dilakukan uji korelasi Spearman’s rho. Hasilnya diperoleh nilai p value (0,006) < 0,05. dengan demikian dapat disimpukan bahwa terdapat hubungan antara kepuasan terapi dengan kualitas hidup pasien penderita DM type-2.

Kata Kunci: Diabetes melitus tipe 2, Kepuasan Terapi dan Kualitas Hidup
Analisa Kualitas Hidup Pembalap Motor Road Race Pasca Mengalami Cedera Tulang Di Jawa Barat Menggunakan European Quality Of Life 5 Dimensions (EQ5D) EQ-5D-5L
Authors: Dedy Frianto  , Riska Novrianty  
Published: November 2020

Olahraga balap motor khususnya Road Race cukup populer di Indonesia. Olah raga ini merupakan aktivitas yang dapat memberikan manfaat bagi kesehatan fisik maupun mental. Namun, jika tidak diimbangi kesadaran untuk menjaga keselamatan, sehingga mereka sangat rentan mengalami cedera yang dapat mengganggu kesehatan juga dapat mengurangi atlet tersebut untuk berprestasi secara maksimal. Penelitian ini bertujuan mengidentifikasi dan menganalisa bagaimana kualitas hidup para pembalap motor Road Race pasca mengalami cedera tulang dan terapi atau obat apa digunakan oleh para pembalap pasca mengalami cedera tulang tersebut.
Sampel penelitian ini adalah para pembalap yang diketahui telah mengalami cedera atau patah tulang di Jawa Barat. Desain penelitian menggunakan jenis Observasional Cross Sectional di mana pengumpulan data dilakukan dengan pengisian kuesioner secara prospektif pada semua pembalap di Jawa barat. Pengumpulan data dilakukan dengan menyebarkan kuesioner European Quality Of Life 5 Dimension (EQ5D5L) secara langsung kepada para pembalap pada Event Bupati Cup Seri 1 – Open Road Race 2.
Berdasarkan analisa data yang dilakukan, diperoleh kesimpulan bahwa kualitas hidup para pembalap pasca mengalami cedera tulang memiliki kualitas hidup yang baik karena didapatkan hasil rata-rata dari skala kesehatan terakhirnya yaitu 0,4888, di mana apabila responden memiliki skala kesehatan 1,000 atau lebih dari -0,594, maka responden dinyatakan memiliki kualitas hidup yang baik pasca mengalami cedera tulang.

Kata Kunci: Road Race, Pembalap, Cedera tulang, Kualitas hidup, EQ5D5L

The purpose of this study is to find out the most optimal formulation and to find out the physical evaluation results of white glutinous rice extract sheet mask preparations. The method of making experimental formulations using CMC Na as viscosity-increasing agent with F1 concentration (0,2%); F2 (0,3%); and F3 (0,4%). The evaluations carried out are organoleptic test, homogeneity test, pH test, viscosity test, preference test and irritation test. The results showed the essence preparation in the form of a thick solution with a characteristic odor and pale white and homogeneous. PH values ​​of F1 preparations (4,92 ± 0,01), F2 (4,95 ± 0,01), and F3 (4,97 ± 0,02). Viscosity F1 (145,47±10,02 cPoise), F2 (180,37±3,63 cPoise), and F3 (194,80± 18,56 cPoise). The preference test with 32 respondents shows that the average preference for essence color is neutral / ordinary, for aroma is like and for essence texture is neutral / ordinary. Irritation testing on 30 volunteers showed the result that the preparation of white glutinous rice sheet mask was safe with the irritation index value obtained 0.004 (no means).

Keyword: white glutinous rices, sheet masks, CMC Sodium.
FORMULASI, UJI STABILITAS FISIK DAN KOMPATIBILITAS PRODUK KOSMETIK ANTI-AGING DALAM SEDIAAN SERUM PUDDING
Authors: Farhamzah  , Aeni Indrayati  
Published: November 2020

Serum adalah salah satu sediaan kosmetik berbentuk gel yang digunakan untuk produk anti-aging dan bentuk gel dari sediaan bisa dibuat lebih menarik sebagai variasi dari bentuk serum yang sudah ada. Maka dilakukan penelitian formulasi produk anti- aging dengan sediaan berbentuk serum yang mempunyai tekstur seperti Pudding. Formulasi menggunakan bahan baku polimer dengan konsentrasi 5% dengan perbedaan formula pada konsentrasi parfum. Hasil formulasi dilakukan uji sediaan berupa pemeriksaan organoleptik, pH, viskositas, kelembaban, after feel, rasa lengket, rasa panas, rasa gatal, Uji Stabilitas dan Uji Kompabilitas selama 12 minggu. Hasil penelitian menunjukkan bahwa formula yang tidak menggunakan parfum memberikan hasil stabilitas dan kompabilitas yang baik.

Kata Kunci : Stabilitas Fisik, Kompatibilitas, Anti-Aging, Serum Pudding
Serum is one of the gel-shaped cosmetic preparations used for anti-aging products and the gel form of the preparation can be made more attractive as a variation of the existing serum form. Then do research on anti-aging product formulations with serum-shaped preparations that have a texture like Pudding. The formulation uses a polymer raw material with a concentration of 5% with different formulas at the Perfume concentration. The results of the formulations were tested in the form of organoleptic tests, pH, viscosity, humidity, after feel, stickiness, burning sensation, itching, Stability Test and Compatibility Test for 12 weeks. The results show that formulas that do not use perfume provide good stability and compatibility results.

Keywords: Stability Test, Compatibility Test, Anti-Aging, Pudding Serum
Comparison on Effects of Temperature on Different Strains of Phytase Producing Bacteria Isolated from Malaysia’s Hot Spring
Authors: Anis Adilah Mustafa  , Nurul Asma Hasliza Zulkifly  , Afnani Alwi@Ali  , Tajul Afif Abdullah  , Nadiawati Alias  
Published: November 2020

The main purpose of this research was to find the best growth curve for bacterial growth and the optimum temperature for the production of phytase from different potential phytase producing bacterial strains. A total of four strains used were originally isolated from hot springs in Malaysia, which were in Labis, Johor (L3), Dusun Tua, Selangor (RT), Ulu Legong, Kedah (A) and Ranau, Sabah (B9). Nutrient Agar (NA) and modified Phytase Screening Medium (PSM) liquid media were used for the culture enrichment while optimisation was carried out through batch culture method using a shake-flask scale. Strains growth and enzyme activity were quantitatively measured at different temperatures at (30°C and 37°C) values. Enzyme activity was determined according to the reaction of the phytase with its substrate (sodium phytate) and expressed in units of phytase activity (U/ mL). As for the overall, strain L3 (from Labis, Johor) exhibit promising rate of Pi released in the media at 30°C and 37°C, with optimum phytase activity values of 0.2047 U/mL and 0.2195 U/mL, respectively. The pH of the cultures was also measured, where it shows that strains grown in cultures at 37°C produced a higher phytase activity and resulting a lower reading of pH compared when grown at 30°C. All around, L3 strains has the lowest value of pH when cultured at 30°C and 37°C, with the pH value of 3.62 and 2.37, respectively. From the result obtained, the lower pH indicates the process of phytic acid degradation take place by the phytase in producing inorganic phosphate (Pi) due to the accumulation of organic acid. Since these bacterial strains were originally taken from Hot Springs, further analysis of temperature optimization using 55°C and even 60°C should be carried out. In the future, biochemical research and molecular identification may also be carried out to identify molecular identity in the strains.
Analisis Yuridis Perkawinan Dibawah Umur Melalui Kewenangan Kantor Urusan Agama (Studi Kasus di KUA Kabupaten Bantaeng)
Authors: Hamzah Yuli Adha , Mangarengi Arianty Anggraeny , Buana Andika Prawira 
Published: November 2020

Dewasa ini marak terjadi perkawinan dibawah umur yang menyebabkan implikasi hukum yang negatif, salah satu daerah yang menjadi tempat maraknya prakter tersebut terdapat di kabupaten bantaeng, dimana perkawinan dibawah umur terus terjadi dan mulai meresahkan masyarakat. Tujuan penelitian ini adalah ingin mengetahui kewenangan Kantor Urusan Agama terhadap legalitas perkawinan dibawah umur serta untuk mengetahui faktor - faktor yang mempengaruhi terjadinya perkawinan dibawah umur. Penelitian ini menggunakan tipe penelitian kualitatif dengan pendekatan yuridis empiris. Penelitian ini dilaksanakan di Kantor Urusan Agama Kabupaten Bantaeng. Hasil penelitian ini menunjukkan bahwa tidak efektifnya pelaksanan Undang - Undang Perkawinan karena masih terdapatnya beberapa perkawinan dibawah umur yang terjadi dengan dalih adanya permohonan dispensasi perkawinan serta masih terdapatnya beberapa penyimpangan - penyimpangan hukum dalam hal prosedur pelaksanaan perkawinan dibawah umur oleh oknum Kantor Urusan Agama, dan hasil penelitian lain menunjukkan terdapat 5 (lima) faktor yang mempengaruhi kewenangan Kantor Urusan Agama terhadap legalitas perkawinan dibawah umur antara lain faktor pengetahuan hukum, faktor aparat hukum, faktor budaya hukum, faktor hamil diluar nikah dan faktor ekonomi. Faktor-faktor tersebut menjadi alasan kuat mengapa perkawinan dibawah umur ini masih terus terjadi.
Abstract. Nowadays underage marriages are rampant which causes negative legal implications, one of the areas where this practice is rampant is in Bantaeng district, where underage marriages continue to occur and begin to disturb the community. The purpose of this study was to determine the authority of the Office of Religious Affairs on the legality of underage marriage and to determine the factors that influence the occurrence of underage marriage. This study uses a qualitative research type with an empirical juridical approach. This research was conducted at the Office of Religious Affairs in Bantaeng Regency. The results of this study indicate that the implementation of the Marriage Law is ineffective because there are still several underage marriages that occur on the pretext of the existence of applications for marriage dispensation and there are still several legal irregularities in the procedure for implementing underage marriage by persons in the Office of Religious Affairs, and the results Other research shows that there are 5 (five) factors that influence the authority of the Office of Religious Affairs on the legality of underage marriage, including legal knowledge, law enforcement factors, legal culture factors, extramarital pregnancy factors and economic factors. These factors are strong reasons why underage marriages continue to occur.
Amelioration of Murine Autoimmune Pancreatitis by Targeted LTβR Inhibition and Anti-CD20 Treatment
Authors: Wanner-Seleznik Gitta M , Reding Theresia , Chen Rong , Gupta Anurag Kumar , Lenggenhager Daniela , Browning Jeffrey , Segerer Stephan , Heikenwalder Mathias , Graf Rolf 
Published: November 2020

Abstract
Autoimmune pancreatitis (AIP) is a rare form of chronic pancreatitis, for which treatment options, especially the long-term management, are limited. The only therapy that has been established and accepted so far is corticosteroids, but the relapse rate is significant. In the current study, we discern the effector mechanisms of targeted LTβR pathway inhibition using LTβR-Ig. Furthermore, the efficacy of LTβR-Ig therapy is compared with the depletion of immune cell subsets (CD4+ and CD20+), which are suggested to play a pathological role in AIP development. Three well-established mouse models of AIP were used to examine treatment efficacies and mechanisms. Tg(Ela1-Lta,b) mice represent a genetic model, in which AIP develops spontaneously. In MRL/Mp and IL-10−/− mice, AIP is induced by repeated polyinosinic:polycytidylic acid injection. Mice with AIP were treated with anti-CD20, anti-CD4 mAbs, or targeted LTβR-Ig. LTβR-Ig and anti-CD20 treatment led to significant improvement of AIP, including a decrease in autoantibody production and pancreatic inflammation in Tg(Ela1-Lta,b) and IL-10−/− mice. The molecular mechanism of this beneficial effect possibly involves the downregulation of Stat3 and noncanonical NF-κb activation. Anti-CD4 treatment reduced Th1 and Th2 signature but did not alleviate AIP. Additionally, in contrast to anti-CD20 or anti-CD4 treatments, blocking LTβR signaling disrupted tertiary lymphoid organs in all three models. We demonstrate that treatment with LTβR-Ig or anti-CD20 Ab alleviated murine AIP. LTβR-Ig treatment for AIP was effective in both lymphotoxin-dependent and lymphotoxin-independent AIP models, possibly because of its dual anti-inflammatory and antiautoimmune mechanisms.
Farmacogenetica e Farmacogenomica: aspettative e questioni etiche
Authors: Spagnolo A.G. , Minacori R. 
Published: November 2020

La farmacogenetica è stata inizialmente definita come lo studio della variabilità di risposta individuale al farmaco legata all’ereditarietà e alle caratteristiche genetiche personali e familiari. Durante l’ultima decade il termine farmacogenomica ha ulteriormente affinato tale definizione delineando con più precisione gli ambiti e le finalità di questo nuovo ambito scientifico. L’obiettivo è ancora più affascinante e importante: sviluppare e utilizzare nuove terapie farmacologiche personalizzate, più efficaci e meno dannose, utilizzando le scoperte sul genoma umano.
Dallo sviluppo di questa nuova applicazione della genetica probabilmente dipenderà anche un mutamento nella prassi medica, con nuovi criteri diagnostici e soprattutto nella possibilità di somministrare delle terapie personalizzate.
La genomica applicata alla ricerca farmacologica, oltre alle diverse problematiche tecnico-scientifiche che ancora sono in via di risoluzione, impone anche, per l’ambito di applicazione - il genoma umano, quindi anche la persona umana, e le finalità che si prefigge cioè pervenire a nuove e ottimali soluzioni terapeutiche attraverso la ricerca clinica - un’ampia riflessione etica rispetto ad una pluralità di elementi in gioco.
D’altra parte occorre anche considerare che ai vantaggi di una quota di popolazione potrebbero correlarsi svantaggi terapeutici per altre fasce di popolazione minoritarie, perciò è fondamentale che un’ampia e articolata riflessione e adeguate soluzioni vengano intraprese prima che la commercializzazione dei tests farmacogenetici possa causare discriminazioni tra i pazienti.
Nell’articolo, gli Autori evidenziano le questioni etiche relative alla ricerca farmacogenetica di base, all’identificazione, alla collezione e alla brevettabilità dei dati, alla ricerca farmacogenetica applicata, con lo sviluppo di dispositivi diagnostici e il loro uso nelle sperimentazioni cliniche, alle procedure per la conservazione e dei campioni biologici e dei dati e per la tutela della riservatezza, al ruolo dei Comitati di Etica nella valutazione dei protocolli sperimentali di farmacogenetica, al consenso informato per i soggetti di sperimentazione.
La comunicazione medico-paziente: elementi per una fondazione etica
Authors: Carrasco De Paula Ignacio 
Published: November 2020

L’articolo prende in esame gli aspetti etici di un tipo particolare di comunicazione, quella tra il medico e il suo paziente.
L’Autore introduce l’argomento con alcune osservazioni di natura storicodottrinale (dialettica tradizione-modernità) e prosegue con una riflessione sulle categorie e condizioni etiche pertinenti ad una attività specificamente umana e, pertanto, morale, quale è la comunicazione tra il medico e il paziente.
In particolare, vengono trattate le seguenti questioni: a. pregi e limiti della comunicazione medico-paziente nella medicina tradizionale (Corpus Ippocratico); b. l’avvento della tecnologia nella medicina della modernità (conquiste e insidie); c. le basi etiche della comunicazione medico-paziente nel contesto clinico.
Dynamics and Stability in the Encounters between Asian Buddhists and European Christians
Authors: Berkwitz Stephen C. 
Published: November 2020

The aim of this paper is to theorize broadly about how cultural encounters between Asian Buddhists and European Christians spurred various efforts to demarcate, systematize, and stabilize religious traditions. It focuses on the dynamics seen in Buddhist responses to contact situations from the sixteenth century onwards in Sri Lanka, Cambodia, and Japan in order to map out some patterns of interaction among these communities. Theories of cultural imitation and independence do not suffice to theorize interreligious encounters in these cases. Using select examples, this paper will contend that Asian Buddhists often responded to various kinds of European interventions by redefining and reimagining the Buddhist tradition in new ways in order to argue for its continued validity and to secure its stability in the face of external encounters and pressures.
Representation of Transcendence. The Armenian Letter “On the Image-Fighters” from the Seventh Century CE
Authors: Jurczyk Thomas 
Published: November 2020

The major aim of this article is to study the Armenian Letter “On the Image-Fighters” by Vrt’anes K’ert’oł (approx. seventh century CE) from a religious studies’ perspective by examining the use and the role of representation (through images) in the Letter. The topic of representation is important both for the study of religion as well as for the history of iconoclasm and closely connected to the analytical concept of immanence/transcendence. The peculiarities of the use of representation in the Letter demonstrate that some aspects of the broader notion of representation must be adjusted when talking about religious representation. The approach of this article combines an in-depth investigation of the Letter (including an English translation in the appendix) with comparisons to different semantic layers of the modern notion of representation and the use of representation in Greek (pre-)iconoclastic sources from the same period.
Historical Engagements and Interreligious Encounters - Jews and Christians in Premodern and Early Modern Asia and Africa
Authors: Cuffel Alexandra , Gamliel Ophira 
Published: November 2020

The essays in this special issue are based on the proceedings of the workshop Eastern Jews and Christians in Interaction and Exchange in the Islamic World and Beyond: A Comparative View held in Jerusalem and Raʿanana in June 2016. Accordingly, the essays address interreligious encounters in the Islamic world and beyond, examining social and religious attitudes towards religious Others in a wide range of disciplinary approaches. What binds these essays together is an attempt to shed light on a little-known history of Jewish-Christian relations in premodern Asia and Africa, a subject that stands at the heart of the research project Jews and Christians in the East: Strategies and Interactions between the Mediterranean and the Indian Ocean.
The Lutheran Church in Rodowo as a Place of the Spiritual Meeting of Three Social Strata
Authors: Birecki Piotr 
Published: November 2020

The article presents the hitherto unknown decoration of the furnishing of a little Protestant church in Rodowo in Ducal Prussia, founded by the local aristocratic family ofthe Schack von Wittenaus. After firstly providing an overview of the complicated confessional history of the region, the church, and its patrons, the second part of this article presents the emblematic decoration of church benches based on the “Four Elements,” with models for tapestries designed by Charles Le Brun and published in Paris in 1668 (and later in Germany). The original emblems, with descriptions by Charles Perrault, refer to King Louis XVI as the ideal ruler, but in Rodowo they emphasize the position of the Prussian nobility as the most important social group in the country. The second part of the article presents four unknown easel paintings on the church walls, with a symbolic presentation of Lutheran piety connected with Pietism in Ducal Prussia. The entire artistic ensemble in the church refers to the role of noblemen as leaders in the social and religious life of Ducal Prussia.