bluuebunny/crossref_metadata_2025_split huggingface dataset:
Death and preventable death in trauma patients in a level-1 trauma center in Thailand
Authors: Akaraborworn Osaree , Sangthong Burapat , Thongkhao Komet , Chainiramol Pratthana , Kaewsaengrueang Khanitta 
Published: June 2020

Abstract

Background
Trauma is a major cause of death in young adults. The mortality rate is one of the key performance indices of trauma centers.

Objective
To demonstrate a mortality rate, cause of death, and cause of nonpreventable death in a level-1 trauma center in Thailand.

Methods
There was a retrospective study of the death cases from a trauma registry. The number of trauma deaths during the study period was collected to identify the death rate. The causes of death and a death analysis were obtained from the morbidity and mortality.

Results
The death rate was 6.6%. The most common cause of overall death was head injury, and exsanguination was the most common cause of death in the first 24 h. The preventable death rate was 2%, and the most common cause of preventable death was exsanguination.

Conclusions
The mortality rate of trauma patients in Thailand was not higher than that in other countries. The majority of deaths were caused from head injury. Therefore, improvement in injury prevention is needed to decrease the number of deaths.
Targeting prolyl tripeptidyl peptidase from Porphyromonas gingivalis with the bioactive compounds from Rosmarinus officinalis
Authors: Ramalingam Ashwin Kumar , Selvi Smiline Girija Aseervatham , Jayaseelan Vijayashree Priyadharsini 
Published: June 2020

Abstract

Background
Complications in periodontitis and other systemic infections related to Porphyromonas gingivalis poses a serious impediment in the treatment process. This leads to the search of novel target proteins to develop newer drugs against P. gingivalis. Prolyl tripeptidyl peptidase (ptp-A) seem to be a vital protein in P. gingivalis virulence and can be a good target for the novel natural bioactive compounds.

Objectives
To explore the inhibitory potential of Rosmarinus officinalis biocompounds against the ptp-A of P. gingivalis.

Methods
Three-dimensional structure of ptp-A was retrieved from the Protein Data Bank with further optimization of both the protein and ligands. In silico inhibitory potential of the selected ligands against ptp-A was done by AutoDock 2.0 and was visualized with Biovia discovery studio visualizing tool with the assessment of the molecular properties of the ligands against ptp-A by molinspiration calculations and drug likeliness.

Results
High ptp-A inhibitory effect was observed using rosmarinic acid and luteolin with a bonding energy of −9.81 kcal/mol with 10 hydrogen bond interactions and −9.99 kcal/mol with 7 hydrogen bond interactions, respectively. Carnosic acid and p-coumaric acid showed a binding energy of −7.14 kcal/mol and −6.34 kcal/mol, respectively, with 5 hydrogen bond interactions. Molinspiration assessments showed R. officinalis compounds as the best drug candidates with the topological polar surface area scores <140 Å toward the best oral bioavailability.

Conclusion
The carnosic acid, rosmarinic acid, p-coumaric acid, and luteolin from R. officinalis seem to possess a promising inhibitory effect against ptp-A of Candida albicans suggesting ptp-A as the best target to combat P. gingivalis with further in vivo validation.
Zwischen Ost und West: Zur Druckgeschichte von Schimon Günzburgs jiddischer Brauchsammlung
Authors: Raspe Lucia 
Published: June 2020

AbstractShimʻon Günzburg’s Yiddish collection of customs, first brought to press in Venice in 1589 and reprinted dozens of times over the following centuries, is often considered a mere translation of the Hebrew Minhagim put together by Ayzik Tyrnau in the 1420s. Another claim often made about the book is that, although it was first printed in Venice, it was intended less for the Italian book market than for export. This article sets out to test these assumptions by examining Günzburg’s compilation from the perspective of minhag, or prayer rite. Drawing on Yiddish manuscripts preserved from sixteenth-century Italy, as well as early printed editions overlooked by scholars, it argues that Günzburg’s Minhogim are, in fact, more Italian than has been recognized. It also points up their potential for a comparative history of Ashkenazic book culture across the political and linguistic borders of Europe.
Un fantôme historique : «l’autre Theophane»
Authors: Yannopoulos Panayotis 
Published: June 2020

Abstract
At the beginning of the 9th c. George Syncellus began to write a universal chronicle, the second part of which was completed by the monk Theophanes. According to Byzantine tradition this monk was Theophanes the Confessor. But 10th-century sources note that this Theophanes was the grandfather or greatuncle of the emperor Constantine VII, which is historically impossible. This prompted P. Speck to invent “another Theophanes”, who lived during the second half of the 9th c. and was the editor of the Chronicle of Theophanes. The hypothesis turns out to be unfounded and untenable. Also untenable and unrelated to the sources is the hypothesis of C. Zuckerman that the author of the Chronicle is another Theophanes who lived at the same time as the Confessor. This study, after an analysis of sources, proves in both cases that they are historical phantoms.
Physicochemical evaluation of the fruit pulp of Opuntia spp growing in the Mediterranean area under hard climate conditions
Authors: Bourhia Mohammed , Elmahdaoui Hamza , Ullah Riaz , Ibenmoussa Samir , Shahat Abdelaaty Abdelaziz 
Published: June 2020

AbstractBarbary fig called prickly pear is a plant belonging to family Cactaceae growing under hard climate conditions. A spiny variety of prickly pear named “Drbana” (Opuntia megacantha) and two non-spiny varieties named “Akria” and “Mlez” (Opuntia ficus-indica) growing in the Rhamna region (Morocco) were studied in terms of physicochemical characteristics. The physicochemical characterization (humidity, water activity, pH, total titratable acidity, Brix, and ash content) and the biochemical characterization (total carotenoid content, betalain content, total polyphenolic content, and ascorbic acid content) of the fruit pulp of prickly pear were performed according to the previously reported methods. The finding of physicochemical characterization of all studied varieties showed that the fruit pulp also contained an interesting bioactive compound classes in humidity, water activity, pH, total titratable acidity, Brix, and ash content. Regarding the biochemical characterization, the obtained finding showed the fruit pulp also contained an interesting bioactive compound classes particularly the total betalains, polyphenols, carotenoids, and ascorbic acids. Based on the obtained results in the current research work, we can affirm that the fruits of all studied varieties meet the requirement for being exploited in food, cosmetic, and pharmaceutical industries.
Comparative studies of two vegetal extracts from Stokesia laevis and Geranium pratense: polyphenol profile, cytotoxic effect and antiproliferative activity
Authors: Pirvu Lucia , Neagu Georgeta , Terchescu Iulian , Albu Bujor , Stefaniu Amalia 
Published: June 2020

AbstractIn this study, two ethanolic extracts, fromStokesia aster(Slae26) andGeranium pratense(Gpre36) respectively, were evaluated in order to assess the cytotoxic activity and potential antiproliferative activity upon the nontumorigenic human epithelial cell line derived from the mammary gland (MCF-12A) and the human breast tumor cell line (BT-20). The selection of the plant species was done on the basis of their chemical composition, specifically combinations of luteolin derivatives with caffeic and gallic acid derivatives. Therefore, theS. laevisethanolic extract proved its capacity to inhibit the viability of both normal and tumor breast cell lines (i.e., up to 90% cell viability inhibition, IC50= 42 µg/mL). On the contrary, theG. pratenseethanolic extract proved weak stimulatory effects on the viability of the two human breast cell lines studied. The obtained results were discussed in the contexts of computational studies and drug-likeness bioactivity of seven common luteolin derivatives: luteolin, luteolin-7-O-glucoside/cynaroside, luteolin-5-O-glucoside/galuteolin, luteolin-6-C-glucoside/isoorientin, luteolin-8-C-glucoside/orientin, luteolin-3′,4′-di-O-glucoside and luteolin-7,3′-di-O-glucoside. Computational studies have revealed that the hydrophilic behavior of luteolin derivatives (log Pvalues) does not follow other tested parameters (e.g., polar surface area values), possibly explaining different efficacy concerning the biological propertiesin vitro. These predictions could be a starting point for studies on the biochemical mechanism by which luteolin derivatives induce biological effects.
Numerical Modeling of Phenol Adsorption on Granular Activated Carbon Fixed Bed: Comparison of Two Numerical Methods to Solve the Advection-dispersion Equation
Authors: Kolli Mounira , Semra Safia , Benmahdi Fatiha , Bouhelassa Mohamed , Sardin Michel 
Published: June 2020

Abstract
This paper presents a comparison between some numerical methods and techniques for solving the nonlinear advection-dispersion equation, which may be used to describe the adsorption of phenol into a granular activated carbon fixed bed under local equilibrium conditions. The adsorption is described by the Langmuir isotherm, which makes the advection-dispersion equation nonlinear. This equation is solved successively by using the approximation and linearization techniques. For each technique, two types of numerical algorithms are used. Concerning the first one, the Implicit and the Runge Kutta schemes are used. As for the second one, the Modified Picard iteration and the Newton Raphson scheme are applied. Simulation results have been compared to each other and to the experimental data as well. Both of the Implicit and the Runge Kutta algorithms have led to superimposed simulated breakthrough curves. Both of the modified Picard and Newton Raphson schemes have given identical results too. However, comparing to the experimental data, the obtained solution, using the approximation technique, has underestimated the retardation of solute and failed in fitting the experimental breakthrough. The Obtained solution, using the linearization technique, has correctly fitted the experimental results under all the conditions of: feed flow rate, activated carbon bed height and the inlet phenol concentration.
Integral bridge and culvert design, Designer’s experience
Authors: Helowicz Andrzej 
Published: June 2020

Abstract
This paper describes a small single-span integral bridge made of in-situ concrete. The bridge was designed by the author and built on the M9 motorway between the towns of Waterford and Kilcullen in Ireland. Selected parts of the bridge design are presented. First the principles of modelling and designing integral bridges and culverts are explained. Then the considered bridge’s design is described. The advantages and disadvantages of such structures are discussed. The focus is on the design, construction, cost and in-service behaviour of small integral bridges and culverts. In Conclusions the author shares his knowledge and experience relating to the design of small integral bridges and culverts and puts forward recommendations as to further research on this type of structures in Poland.
Estimation of Sport Facilities by Means of Technical-Economic Indicator
Authors: Hanak Tomas , Hrstka Lukas , Tuscher Martin , Biolek Vojtech 
Published: June 2020

Abstract
This paper is concerned with early cost estimation of sport facilities. Sufficiently precise cost estimation is essential for investors in the pre-investment stage where they decide on whether to pursue an investment and choose a suitable technical solution for the development of the project. Through a detailed analysis of the technical and economic documentation pertaining to seven sport facilities projects assembled using concrete prefabricated beam parts, as well as evaluation of the data thus obtained, three types of technical-economic indicators were set in relation to the enclosed building area, the number of spectator seats and the sports playing area. The results achieved indicate that evaluation of relations between these three indicators could contribute to a more effective use of investment funding on the part of the investor. Other conclusions include the finding that available indicators published by private companies active in the area of construction budgeting are not sufficiently accurate for the purposes of investment decision-making; specifically, these indicators greatly overestimate the costs of sport facilities, which can potentially lead to these projects being rejected. This contribution brings know-how for a more accurate early cost estimation of sport facilities in the Czech Republic which can, thanks to a generally applicable methodology, be used in other countries as well.
From constructions to functions and back: Contrastive negation in English and Finnish
Authors: Silvennoinen Olli O. 
Published: June 2020

Abstract
This is a comparative investigation of contrastive negation in English and Finnish, i. e. combinations of a negated and an affirmed part construed as alternatives to one another. In both languages, there are several constructions that express contrastive negation, but their division of labour remains unclear. The aims of the paper are two-fold: first, to see what constructional strategies are available for contrastive negation in the two languages and, second, to see how the strategies are motivated by its interactional functions. In English, contrastive negation may be expressed by using the adversative conjunction but correctively (e. g. It’s not the bikers but the other vehicle on the road), whereas standard Finnish has a specialised corrective conjunction vaan alongside the adversative mutta. Moreover, many constructions can express contrastive negation, including ones without a conjunction (e. g. It’s not the bikers, it’s the other vehicle on the road). An analysis of conversational data shows that English favours constructions without conjunctions, while in Finnish constructions both with and without conjunctions are frequent. The uses of contrastive negation are divided into reactive and non-reactive. The pragmatic functions largely explain the usage patterns, and these in turn can explain the cross-linguistic regularities of corrective conjunctions.
The syntax and semantics of Modern Standard Arabic resumptivetough-constructions
Authors: Tayalati Fayssal , Danckaert Lieven 
Published: June 2020

AbstractThis paper is concerned with a hitherto undiscussed type oftough-construction in Modern Standard Arabic (MSA). Our starting point is the observation that thetough-adjective in this construction invariably displays nominative masculine singular morphology, a pattern of ‘default’ agreement which does not seem to occur elsewhere in the grammar of MSA. At a semantic level, the relevant adjective is argued to form a complex predicate with a deverbal nominalization that acts as its complement: together, these two elements indirectly modify the subject noun phrase. To explain the default agreement pattern, we propose that MSAtough-constructions involve two distinct subjects, viz. a phonologically null expletive subject which controls agreement on thetough-adjective, and a Broad Subject which acts as the semantic subject of the whole construction. We show that there is independent evidence for the existence of both null expletives and Broad Subjects in MSA.
A quasistatic frictional contact problem for viscoelastic materials with long memory
Authors: Kasri Abderrezak , Touzaline Arezki 
Published: June 2020

Abstract
The aim of this paper is to study a quasistatic frictional contact problem for viscoelastic materials with long-term memory.
The contact boundary conditions are governed by Tresca’s law, involving a slip dependent coefficient of friction.
We focus our attention on the weak solvability of the problem within the framework of variational inequalities.
The existence of a solution is obtained under a smallness assumption on a normal stress prescribed on the contact surface and on the coefficient of friction.
The proof is based on a time discretization method, compactness and lower semicontinuity arguments.
Survey of school nurses’ experiences of providing counselling on sexual orientation to high school students in Japan
Authors: Terao Ryohei , Kaneko Noriyo 
Published: June 2020

Abstract

Objective
To ascertain the prevalence and correlated factors of providing consultation on sexual orientation and the characteristics of school nurses in high schools in Japan.

Methods
Participants were school nurses working in high schools in Aichi prefecture. Items investigated included background, experiences in providing counselling on sexual orientation, the availability of materials and resources for students, and learning experiences concerning how to handle sexual orientation concerns. We divided the respondents into two groups: one group who have provided counselling on sexual orientation before and one group with no such experience. Chi square tests were utilized to compare the responses between groups.

Results
Among the respondents, 38.9% (n = 140) had previous experience of providing counselling to students on sexual orientation. The group with experience of providing counselling is more likely to have 10–29 years of experience, to work at a senior high school, to be informed on notifications from the Ministry of Education, to have experience of learning how to provide counselling on sexual orientation, and to be aware of effective resources.

Conclusion
In Japan, it is expected that the support needs related to LGBTI will become more obvious in the future and efforts to create an environment in which it is easy for young people to consult with school nurses or other support figures are necessary.
Prevalence and associated factors of skipping breakfast among university students from 28 countries: a cross-sectional study
Authors: Pengpid Supa , Peltzer Karl 
Published: June 2020

Abstract

Background
Skipping breakfast can negatively affect one's health.

Objective
The study aimed to assess the prevalence and correlates of skipping breakfast among university students in 28 countries.

Methods
Using a cross-sectional study design, 21,958 university students with a median age of 20 years from 28 mainly low – and middle-income countries, replied to self-reported measures of breakfast consumption, health risk behaviours, mental health measures and protective factors.

Results
Indicates that 48.0% of students skipped breakfast (never, rarely or sometimes had breakfast). In adjusted multinomial logistic regression, living away from home, perceived overweight, inadequate fruit and vegetable intake, physical inactivity, short sleep, long sleep, depression and in a physical fight were associated with infrequent and/or frequent skipping breakfast.

Conclusion
Almost two in five students skipped breakfast, and several factors were identified that can be targeted in intervention programmes.
The importance of Internet systematic search for legal translations
Authors: Giampieri Patrizia 
Published: June 2020

Abstract
The web is a vast and disorganised language resource which is often accessed too naively or superficially by students or inexperienced translators. In this paper, bachelor's students enrolled in a course in translation studies are challenged to translate an extract of a legal document. To complete their translation task, they consulted the language resources they felt comfortable with. Some of them asked for advice to external experts. This helped make the translation task real-life. Despite the language tools used, the students' shortcomings and mistranslations were several. In particular, formulaic expressions were neglected and too many literal or “fanciful” translation candidates were proposed. Afterwards, the students took part in a 2-h lesson where they understood how to consult the web effectively to find reliable information. This paper will highlight that a systematic approach to Google search is necessary in order to deliver high-quality translation work. In particular, advanced search must be performed, together with an accurate consultation of legal documents and of authoritative sources, such as experts' forums or sites.
Kriterien der qualitativen Bewertung wissenschaftlicher Publikationen
Authors: Herb Ulrich , Geith Uwe 
Published: June 2020

Zusammenfassung
Dieser Beitrag beschreibt a) die Ergebnisse einer Literaturstudie zur qualitativen Wahrnehmung wissenschaftlicher Publikationen, b) die Konstruktion eines daraus abgeleiteten Kriterienkatalogs zur Wahrnehmung der Qualität wissenschaftlicher Publikationen sowie c) der Überprüfung dieses Katalogs in qualitativen Interviews mit Wissenschaflterinnen und Wissenschaftlern aus dem Fachspektrum Chemie, Physik, Biologie, Materialwissenschaft und Engineering. Es zeigte sich, dass die Wahrnehmung von Qualität auf äußerlichen und von außen herangetragenen Faktoren, inhaltlichen / semantischen Faktoren und sprachlichen, syntaktischen sowie strukturellen Faktoren beruht.
Conditioned medium from the human umbilical cord-mesenchymal stem cells stimulate the proliferation of human keratinocytes
Authors: Sriramulu Sushmitha , Banerjee Antara , Jothimani Ganesan , Pathak Surajit 
Published: June 2020

Abstract

Objectives
Wound healing is a complex process with a sequence of restoring and inhibition events such as cell proliferation, differentiation, migration as well as adhesion. Mesenchymal stem cells (MSC) derived conditioned medium (CM) has potent therapeutic functions and promotes cell proliferation, anti-oxidant, immunosuppressive, and anti-apoptotic effects. The main aim of this research is to study the role of human umbilical cord-mesenchymal stem cells (UC-MSCs) derived CM in stimulating the proliferation of human keratinocytes (HaCaT).

Methods
Firstly, MSC were isolated from human umbilical cords (UC) and the cells were then cultured in proliferative medium. We prepared and collected the CM after 72 h. Morphological changes were observed after the treatment of HaCaT cells with CM. To validate the findings, proliferation rate, clonal efficiency and also gene expression studies were performed.

Results
Increased proliferation rate was observed and confirmed with the expression of Proliferating Cell Nuclear Antigen (PCNA) after treatment with HaCaT cells. Cell-cell strap formation was also observed when HaCaT cells were treated with CM for a period of 5–6 days which was confirmed by the increased expression of Collagen Type 1 Alpha 1 chain (Col1A1).

Conclusions
Our results from present study depicts that the secretory components in the CM might play a significant role by interacting with keratinocytes to promote proliferation and migration. Thus, the CM stimulates cellular proliferation, epithelialization and migration of skin cells which might be the future promising application in wound healing.