bluuebunny/crossref_metadata_2025_split huggingface dataset:
STUDY OF PRESCRIBING PATTERN OF ANTIMICROBIAL AGENTS IN MEDICINE INTENSIVE CARE UNIT OF A TERTIARY CARE HOSPITAL
Authors: BG DUDHE , D CHAKRAVORTY ASHISH , NN MANKAR , HN PISE 
Published: May 2020

Objective: The objective of the study was to assess the current use of antimicrobial agents (AMAs) and to assess prescription writing as per the WHO guidelines in the medicine intensive care unit (MICU).
Methods: The present study was conducted on admitted patients in MICU of a tertiary care hospital. The demographic and clinical treatment data of patients were collected in specially designed pro forma from the case record form.
Results: Of 400 patients enrolled in the study, 55.50% were male and 44.50% were female. A common indication of AMAs use was infection (61.75%), symptomatic (21.50%), and prophylactic (10.50%) use. In 65% patients, antimicrobial therapy was considered to be rational. The majority of patients have good recovery (61%). Polypharmacy was seen in 89.75% of patients. The average number of drugs prescribed per patient was 8.84±2.55. 1.90±1.20 was average number of AMAs per patient. Commonest AMAs prescribed are ceftriaxone (27.64%), metronidazole, and amoxicillin+clavulanic acid.
Conclusion: This study visibly highlights the practice of polypharmacy, low uses of generic drugs, high usage of antibiotic, and injection. Cephalosporins are the most prescribed AMAs in the ICUs. Remedy of this situation requires regulation, education, awareness, compliance with protocol, and guidelines of AMAs use.
THE IRRATIONAL BELIEFS OF BALINESE FEMALE OFFICE WORKERS
Authors: PURNAWATI SUSY , PRIMAYANTI IDA INTEN DWI , IN ADIPUTRA 
Published: May 2020

Objective: This preliminary study aimed to explore the score of irrational beliefs (IBs) among Balinese female office workers in Gianyar. This is a new and very interesting issue in occupational mental health practice in Bali and Indonesia. The finding of this study will be able to use as information for an authority to create some program improvement for human resources at work setting.
Methods: This study used a cross-sectional study design involved 30 participants. In this study, we measured the IBs score by self-reported questionnaire of the smith IB inventory which contained 24 items statement.
Results: The means age of participants was 40.4 years old and means the length of stay was 15.2. years. In this preliminary study, we found the means score of IBs score was 52.37±10.460 (high score category).
Conclusion: The score of IBs of Balinese female office workers in Gianyar was high score category. This result has a clinical impact as well as the outcome of this study can be used to be a recommendation to the government or organization to create an awareness program to decrease worker’s IBs score in purposing better their mental health, work productivity, and well-being.
Evaluation of intramuscular injection of oxytetracycline for use as an experimental model to induce pain and assess the efficacy of pain mitigation strategies in dairy cows
Authors: Ohlheiser Alex L. , Ahola Jason K. , Baier Faith S. , Callan Robert J. , Lear Andrea S. , Byers Stacey R. , Edwards-Callaway Lily N. 
Published: May 2020

Abstract

OBJECTIVE
To evaluate IM injection of oxytetracycline as an experimental model to induce pain and assess the analgesic efficacy of flunixin meglumine (FM) in dairy cows.

ANIMALS
15 healthy nonlactating Jersey (n = 10) and Holstein (5) cows.

PROCEDURES
In the first of 2 experiments, 5 Jerseys were administered oxytetracycline (10 mg/kg, IM), divided between the right side of the neck and left hind limb. The left side of the neck and right hind limb received sham injections. Cows were also randomly assigned to receive FM (2.2 mg/kg, IV; n = 3) or an equal volume of saline (0.9% NaCl) solution (0.044 mL/kg, IV; control; 2) once daily for 5 days. The mechanical nociceptive threshold (MNT) was measured before oxytetracycline administration and at predetermined times after each injection of the assigned treatment. Experiment 2 was similar to experiment 1 except it involved 5 Jerseys and 5 Holsteins, oxytetracycline was injected only in a hind limb, and the assigned treatment was administered for 10 days.

RESULTS
For both experiments, mean MNT for the oxytetracycline injection site was consistently less than that for the sham injection site in the hind limbs, and mean MNT at the hind limb oxytetracycline injection site for FM-treated cows was greater than that for control cows beginning on day 3.

CONCLUSIONS AND CLINICAL RELEVANCE
IM injection of oxytetracycline in a hind limb reliably induced signs of pain in dairy cows and, with validation, might be useful as an experimental model for assessing pain mitigation strategies in cattle.
Effects of intra-articular administration of lidocaine, mepivacaine, and the preservative methyl parahydroxybenzoate on synovial fluid biomarkers of horses
Authors: Adler Ditte M. T. , Serteyn Didier , Franck Thierry , Jørgensen Elin , Christophersen Mogens T. , Denwood Matt , Verwilghen Denis R. 
Published: May 2020

Abstract

OBJECTIVE
To compare the extent of inflammation and catabolic collagen response in the middle carpal joints (MCJs) of healthy horses following intra-articular injection of 2% lidocaine, 2% mepivacaine, lactated Ringer solution (LRS), or 0.1% methyl parahydroxybenzoate.

ANIMALS
17 adult horses.

PROCEDURES
In the first of 2 experiments, the left middle carpal joint (MCJ) of each of 12 horses was injected with 10 mL of 2% lidocaine (n = 3), 2% mepivacaine (3), or LRS (control; 6). After a 4-week washout period, the right MCJ of the horses that received lidocaine or mepivacaine was injected with 10 mL of LRS, and the right MCJ of horses that received LRS was injected with 10 mL of 2% lidocaine (n = 3) or 2% mepivacaine (3). In experiment 2, the left MCJ of each of 5 horses was injected with 10 mL of 0.1% methyl parahydroxybenzoate. After a 48-hour washout period, the right MCJ of each horse was injected with 10 mL of LRS. Synovial fluid (SF) samples were aseptically collected before and at predetermined times after each injection. Synovial fluid WBC count, neutrophil percentage, and total protein, neutrophil myeloperoxidase, neutrophil elastase, and Coll2-1 concentrations were compared among treatments.

RESULTS
Both lidocaine and mepivacaine induced SF changes indicative of inflammation and a catabolic collagen response, but the magnitude of those changes was more pronounced for lidocaine. Methyl parahydroxybenzoate did not cause any SF changes indicative of inflammation.

CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested that mepivacaine was safer than lidocaine for intra-articular injection in horses.
Preparation of endometrium for frozen embryo transfer cycles
Authors: Petrosyan Yana A. , Syrkasheva Anastasiya G. , Romanov Andrey Yu. , Makarova Nataliya P. , Kalinina Elena A. 
Published: May 2020

Aim. Aim of the study was to the effectiveness of various endometrial preparation protocols in IVF frozen embryo transfer cycles.
Materials and methods. The study included 288 women, which were stratified into two groups depending on the onset of pregnancy: group 1 pregnancy + (n=92), group 2 pregnancy - (n=196). Then endometrium preparation features were evaluated.
Results. The pregnancy rate after frozen-thawed embryo transfer was a bit higher in the natural menstrual cycle (41.2%) compared to the hormonal replacement therapy (30.0%); p=0.083. There were no significant differences in the use of various estrogen and progestogen drugs, the average estrogen dose, progestogen administration and the endometrium thickness. In the natural cycle, the odds ratio of pregnancy with the duration menstrual cycle from 28 to 30 days was 4.25 (95% CI 1.15; 17.23).
Conclusion. Thus, the pregnancy rate is slightly higher in natural cycle frozen-thawed embryo transfer. However, the duration of the menstrual cycle (from 28 to 30 days) has a key effect on the effectiveness of the IVF program in this case.
Quantum chemical approach to calculating the enthalpies of the formation of alkali metal xanthates
Authors: Popov Yu. V. , Dolgachev A. S. , Shishkin E. V. , Zotov Yu. L. , Shishkin V. E. 
Published: May 2020

Objectives. The aim of this work is to study the possibility of the joint use of quantum chemical methods and correlation analysis to determine the formation enthalpies of metal-containing organic substances using the example of alkali metal xanthates, which are of interest as biologically active substances and effective flotation reagents. Methods. Semi-empirical methods of quantum chemical calculating (Modified Neglect of Diatomic Overlap, Austin Model 1, Recife model 1 methods) and linear regression analysis were used. Results. Using the semi-empirical Modified Neglect of Diatomic Overlap, Austin Model 1, and Recife model 1 methods, the enthalpies of formation of 16 potassium and sodium alkyl xanthates were calculated, and the obtained results were compared with experimental data. It was found that the best correlation for potassium and sodium salts of dithiocarbonic acid esters could be observed using the Austin Model 1 method. Using the obtained regression equations, the enthalpies of formation were calculated for 30 xanthates, the organic part of which contained alkyl, cyclic non-aromatic structures, and one or two heteroatoms such as nitrogen, oxygen, and fluorine, and for which there are no experimental data. Conclusions. As a result of the study, an excellent correlation was established between the experimental and the calculated (by the Austin Model 1 method) values of the enthalpies of formation of potassium and sodium alkyl xanthates. The data obtained can be used to calculate the thermal effect of the xanthogenation reactions of alcohols and to design the production of the corresponding xanthates.
A Review on Phytochemical Constituents of Abutilon indicum (Link) Sweet - An Important Medicinal Plant in Ayurveda
Authors: Suryawanshi Venkat S , Umate Suvarna R 
Published: May 2020

Abutilon indicum (Link) Sweet is a medicinal shrub belonging to the family Malvaceae; It has been extensively used as a traditional medicine to cure different diseases. It is considered invasive on certain tropical islands. The plant is very much used in Ayurveda & Siddha medicines in Tamilnadu. In fact, the bark, root, leaves, flowers and seeds are all used for medicinal purposes. The phytochemical analysis showed the Presence of alkaloid, saponins, amino acid, flavonoids, glycosides and steroids. Some important essential oil constituents like α-pinene, mucilage, tannins, caryophyllene, asparagines, caryophylleneoxide, endesmol, farnesol, borenol, geraniol, geranyl acetate, elemene and α-cineole have been reported from plant. Phytoconstituents like β‐Sitosterol, caffeic acid, fumaric acid, vanillin, p‐coumaricacid, p‐hydroxybenzoic acid, sesquiterpene including lactones, alantolactone and isoalanto‐lactone along with this hexoses, n-alkane mixtures (C22-34), alkanol, gallic acid also been reported from different part of the plant. The present paper provides detailed review of literature on the phytochemical properties of A. indicum (Link) Sweet, which may be helpful to establish effective and useful natural drugs for further research.
Strategi Pemasaran Pada Umkm Kerajinan Anyaman Plastik di Desa Karanggebang Kecamatan Jetis Kabupaten Ponorogo
Authors: Ulfah Ika Farida , Mustoffa Ardyan Firdausi , WIjianto Wijianto 
Published: May 2020

Kegiatan IbM ini akan dilaksanakan pada pelaku UMKM anyaman plastik di Desa Kranggebang, Kecamatan Jetis, Kabupaten Ponorogo. Permasalahan yang dihadapi oleh pelaku UMKM yaitu selama ini promosi yang dilakukan masih sangat minim karena hanya bergantung pada satu pengepul saja, bahkan pada bulan Januari sampai bulan Mei tidak ada penjualan karena pengepul tidak membeli produk anyaman tas tersebut. Dengan menoptimalkan pemasaran maka produk lebih dikenal luas dan dapat meningkatkan penjualan UMKM tersebut. Tujuan dari kegiatan pengabdian ini adalah selain untuk melaksanakan tri darma perguruan tinggi dalam hal pengabdian kepada masyarakat juga untuk membantu mitra, memberikan solusi atas permasalahan berkaitan dengan aspek pemasaran antara lain adalah mempeluas pemasaran yang selama ini hanya dilakukan kepada pengepul secara offline menjadi pemasaran online dengan memanfaatkan media social dan marketplace agar produk lebih dikenal masyarakat luas. Atas bantuan dari Dinas Perdagkum Ponorogo saat ini pelaku UMKM telah bergabung pada Komunitas Pengrajin Ponorogo, sehingga diharapkan para pelaku UMKM Anyaman Plastik Di Karanggebang Jetis mendapatkan informasi bilamana ada kegiatan Pameran dalam upaya perluasan pasar dan juga pelatihan-pelatihan yang diselenggarakan oleh DInas Perdagkum Ponorogo.. Kata Kunci: manajemen pemasaran, pemasaran online.
Different Perspectives on Higher Education
Authors: Dean Shannon , Sevart Amber 
Published: May 2020

After visiting four higher education institutions within Germany, reflections on the similarities and differences among the student services counterparts in Europe – both at institutional and federal levels are discussed. Studentenwerk serves as a voluntary association of Germany’s 58 student service organizations, known individually as Studentenwerke. This reflection explores the variety of student services offered in the United States and in Germany through these Studentewerke organizations. Additionally, reflection on the differences in the way higher education is viewed at a societal level is also explored.
Cultural intelligence, Age and Prior Travel Experience as Predictors of Acculturative Stress and Depression among International Students Studying in China
Authors: Gebregergis Werede Tareke , Huang Fei , Hong Jiangzhong 
Published: May 2020

Mental health problems commonly prevail among international students as a result of acculturative difficulties. In light of this, the studyattempted to determine the role of cultural intelligence, age and prior travel experience on acculturative stress and depression and also whether acculturative stress mediatedthe cultural intelligence-depression relationship. 506international university students studying in China completeda battery of tests assessing their cultural intelligence, acculturative stress and depression. Cultural intelligence showed significantly negativecorrelationswith both acculturative stress and depression. Students’ prior travel experiences and age also significantlycorrelated withboth acculturative stress and depression. Acculturative stress mediated the relationship between cultural intelligence and depression. Implication, limitations and future study directions were discussed as well.
The Prevalence of Risk Factors for Coronary Artery Disease in Post Coronary Artery Bypass Graft Patients
Authors: Roy Siba Pada , Sarker Pradip Kumar , Khalilullah Ibrahim , Rahman Ahsan Habibur , Sarker Sutapa , Rokonujjaman Mohammad 
Published: May 2020

Background: Cardiovascular diseases, the part of non communicable diseases are the 30% death in Bangladesh. Many patients undergoing coronary artery bypass graft surgery have previous cardiovascular risk factors which could be prevented.
Objectives: To assess the prevalence of cardiovascular risk factors in the patients undergoing coronary artery bypass graft surgery.
Materials and Methods: All patients who had coronary artery bypass grafting between January 2018 to June 2018 data were collected retrospectively in six month duration time at a tertiary cardiac care hospital in Dhaka, Bangladesh. The prevalence rate of conventional risk factors are presented for observational study.
Results: Out of 305 patients, 251 (82.3%) were male and 54 (17.7%) were female. The age ranged from 31 to 78 years old. The mean age was(56.72 ± 3.6). Hypertension was present in 249 (81.6% ),diabetes 211 (69.2%), Dyslipidemia had 200 ( 65.6% ), smoking habits had 105 (34.4%) and strong family history 9 (3%). As far as the obesity was concern 149 (48.9%)normal weight,128 (42.0%) patients were overweight and 25(8.2%) were obese. Majority of the patients had 3 risk factors together 136(44.6%), 2 risk factors 82 (26.9%), 1 risk factor 41(13.4%), 4 risk factors 38(12.5%) and 8(2.6%) had no risk factors. As compared to using the bypass technique there were 242(79.4%) On pump arrest heart, 40(13.1%) by On pump beating and 23(7.5%) were by Off pump beating. Mortality was 2.3%.Out of them 3(42.86%) patients had 3 risk factors, 2 (28.57%) patients had 2 risk factors and 2(28.57%) patients had 1 risk factor.
Conclusion: The most common risk factors were hypertension, followed by diabetes, dyslipidemia , male gender, smoking, obesity and positive family history. These patients are recommended to be trained regarding lifestyle changes. Also, prevention strategies can play an important role in reducing patients' morbidity and mortality.
KYAMC Journal Vol. 11, No.-1, April 2020, Page 9-13
Distribution of Microorganisms in Neonatal Sepsis and Possible Outbreak of Enterobacter spp. in Neonatal Intensive Care Unit
Authors: Rahman Tania , Rahman Md Anisur , Alo Kamrunnahar , Begum Momtaz , Sarwar Sharmin , Nila Sharmeen Sultana 
Published: May 2020

Background: Neonatal sepsis is one of the leading causes of neonatal mortality and morbidity globally, more in developing countries. Frequent monitoring of changing pattern of pathogens causing neonatal sepsis is mandatory for effective treatment.
Objectives: This study was done to isolate and identify different organisms of sepsis and to compare different types of organisms between early-onset neonatal sepsis (EONS) and late-onset neonatal sepsis (LONS).
Materials and Methods: This cross sectional descriptive study was conducted in Department of Microbiology in collaboration with Department of Neonatology, (DMCH) Dhaka. Blood sample was collected from 106 clinically suspected septicemic neonates and isolation and identification of organism was done by automated blood culture and standard microbiological protocol. Data was collected from attendants by filling a predesigned questionnaire.
Results: Among 106 samples, 76 (71.69%) were bloodculture positive. Prevalence of (LONS) was higher 42 (55.26%) in comparison to (EONS) 34 (44.74%). Male neonates were affected more 42 (55.26%) than female 34 (44.74%). Among the isolated organisms, Enterobacter spp. was the predominant organism 20 (26.31%) followed by Klebsiella pneumoniae 18 (23.68%) and Candida spp. 12 (15.79%).
Conclusion: Gram-negative organisms play the leading role for causing neonatal sepsis and Enterobacter outbreak should be concerned. Therefore, regular surveillance of organism profile causing neonatal sepsis is of utmost necessity.
KYAMC Journal Vol. 11, No.-1, April 2020, Page 14-20
Prostatic Lesion and Its Relation with Serum Concentration of PSA
Authors: Haque Abu Sazzad Muhammad Fazlul , Islam Abu Sharif Mohammad Akramul , Biswas Sailendranath , Kabir Md Faisal 
Published: May 2020

Background: Prostate-specific antigen (PSA) is a protein produced by the cells of the prostate gland. It is generally increased in diseases such as prostatitis, hyperplasia and malignancy, but the correlation between various pathology affecting the prostate gland and their corresponding rise in PSA values is not constant, and exception may occur.
Objectives: The aim of this study was to find out the spectrum and distribution of various prostatic lesions affecting men, with respect to their age and to find out the correlation between serum total PSA and histological findings.
Materials and Method: From January 2016 to March 2019, a total of 166 patients in the age group of 39-95 years who underwent histopathology. The reports were studied retrospective and prospectively. Of these patients, 63 were being nodular hyperplasia of prostate. 70 were with existing prostatitis and 33 were adenocarcinoma. The PSA levels were estimated in our Biochemistry Department.
Results: The cases were distributed in the age group 39 to 95years.The patient of adenocarcinoma was 33 and its mean value of PSA was 1164.19 ng/ml, in case of prostatitis number of patient was 70 and its mean value was 12.74ng/ml, prostatic hyperplasia patient was 63 and mean value was 5.2ng/ml.
Conclusion: The result indicate that the chances of malignancy with increasing value of PSA are more but not a rule. It can only give a clue to the histopathologist to examine the sections more thoroughly.
KYAMC Journal Vol. 11, No.-1, April 2020, Page 42-45
Caracterização de altas temperaturas e identificação de épocas suscetíveis à estenospermocarpia em mangas ‘Palmer’
Authors: Santiago Edgo Jackson Pinto , Freire Ana Karla da Silva , Cunha Ana Luíza Xavier , Cantalice José Ramon Barros , Mouco Maria Aparecida do Carmo , Cunha Filho Moacyr , Gomes-Silva Frank , Silva Antonio Samuel Alves da , Oliveira Gertrudes Macario de 
Published: May 2020

O polo agroexportador da região do Submédio do Vale do São Francisco se destaca no agronegócio nacional pelo cultivo de manga e uva, entretanto vem aumentando a vulnerabilidade aos eventos climáticos extremos associados a elevações térmicas nos cultivos de manga Palmer. Essa cultivar vem produzindo frutos estenospermocárpicos com grande frequência quando o florescimento e desenvolvimento inicial dos frutos coincidem com épocas de temperaturas mais elevadas. Dessa forma, estudo capaz de traçar perfil da ocorrência de altas temperaturas na região pode ser importante para determinar de forma precisa, riscos de produção associado extremos térmicos o longo do ano. Este estudo teve como objetivo caracterizar a temperatura máxima do ar em escala mensal por meio de elementos estatísticos descritivos, bem como identificar período com maior potencial a indução de estonepermocarpia em mangueira cv. Palmer na região do Submédio do Vale do São Francisco. Para análise gráfica da série de dados construiu-se em cada mês um histograma de frequência das temperaturas máximas observadas, o qual foi sobreposto pela função densidade de probabilidade Normal. Utilizaram-se os seguintes elementos estatísticos descritivos: média, moda e mediana, variância e desvio padrão. Utilizou-se ainda medidas de assimetria e curtose. O uso da média isoladamente na caracterização térmica da região do Submédio do Vale do São Francisco pode trazer inconsistência e fragilidade nas informações extraídas a partir dela, devido ao considerável grau de incerteza e inadequação, caso o estabelecimento de ocorrência de extremos térmicos não faça uso de ferramentas estatísticas que detecte variabilidade térmica. Dessa forma a utilização dos elementos estatísticos descritivos empregados neste estudo mostrou-se viável para caracterização de extremos térmicos na região do Submédio do Vale do São Francisco. Novembro tende a ser caracterizado como o mês de maior risco à florada da manga cv. Palmer, com verificação de temperaturas máximas extremas apresentando a maior média mensal, 34,1°C e frequente ocorrência de temperaturas de 37,5°C, portanto o período mais sujeito à estenospermocarpia.