bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of standardized post-coercion review session on symptoms of PTSD: results from a randomized controlled trial
Authors: Wullschleger Alexandre , Vandamme Angelika , Mielau Juliane , Renner Lara , Bermpohl Felix , Heinz Andreas , Montag Christiane , Mahler Lieselotte 
Published: November 2020

Abstract
Objective
Post-coercion review is increasingly regarded as a mean to reduce the negative consequences of coercive interventions, including the development of posttraumatic symptoms. However, the efficacy of this intervention in preventing posttraumatic symptoms or PTSD has not been sufficiently studied. The objective of this study is to examine the influence of a single, standardized post-coercion review session on the development or exacerbation of PTSD symptoms in patients with psychotic disorders.

Methods
In a multi-center, two-armed, randomized controlled trial, patients who experienced coercive interventions during current hospitalization were either randomized to standard treatment or an intervention group receiving a guideline-based, standardized reflecting review session. Factorial MANCOVA and subsequent ANCOVAs investigated the effects of the post-coercion reflecting review session on post-traumatic symptoms as measured by the subscales of the Impact of Events Scale-Revised (IES-R). Similarly, the effect of the intervention on the intensity of the peritraumatic reactions measured by the Peritraumatic Distress Inventory (PDI) was analyzed by conducting a factorial ANCOVA.

Results
N = 82 patients were included in an intention-to-treat analysis. MANCOVA and post hoc ANCOVAs revealed a significant main effect of the intervention for the IES-R subscales intrusion and hyperarousal, when controlling for levels of peritraumatic distress, whereby intervention group participants presented lower respective mean scores. There was no significant difference regarding the intensity of the peritraumatic reaction.

Conclusion
Standardized post-coercion review contributes to a reduction of the burden of PTSD symptoms in patients with psychotic disorders experiencing coercive interventions in acute settings and shall be recommended as a measure of trauma-informed care.
The trial was registered at ClinicalTrials.gov (ID NCT03512925) on 01/30/2018 (retrospectively registered).
Mitochondrial DNA analysis efficiently contributes to the identification of metastatic contralateral breast cancers
Authors: Girolimetti Giulia , Marchio Lorena , De Leo Antonio , Mangiarelli Miriam , Amato Laura Benedetta , Zanotti Simone , Taffurelli Mario , Santini Donatella , Gasparre Giuseppe , Ceccarelli Claudio 
Published: November 2020

Abstract
Purpose
In daily practice, a contralateral breast cancer (CBC) is usually considered as a new independent tumor despite the indications of several studies showing that the second neoplasia may be a metastatic spread of the primary tumor. Recognition of clonal masses in the context of multiple synchronous or metachronous tumors is crucial for correct prognosis, therapeutic choice, and patient management. Mitochondrial DNA (mtDNA) sequencing shows high informative potential in the diagnosis of synchronous neoplasms, based on the fact that somatic mtDNA mutations are non-recurrent events, whereas tumors sharing them have a common origin. We here applied this technique to reveal clonality of the CBC with respect to the first tumor.

Methods
We analyzed 30 sample pairs of primary breast cancers and synchronous or metachronous CBCs with detailed clinical information available and compared standard clinico-pathological criteria with mtDNA sequencing to reveal the metastatic nature of CBCs.

Results
MtDNA analysis was informative in 23% of the cases, for which it confirmed a clonal origin of the second tumor. In addition, it allowed to solve two ambiguous cases where histopathological criteria had failed to be conclusive and to suggest a clonal origin for two additional cases that had been classified as independent by pathologists.

Conclusion
Overall, the mtDNA-based classification showed a more accurate predictive power than standard histopathology in identifying cases of metastatic rather than bilateral breast cancers in our cohort, suggesting that mtDNA sequencing may be a more precise and easy-to-use method to be introduced in daily routine to support and improve histopathological diagnoses.
Therapie der angeborenen Thoraxfehlbildungen – Rückblick und Ausblick
Authors: Weinhandl Anja Christina , Rebhandl Winfried 
Published: November 2020

ZusammenfassungThoraxfehlbildungen umfassen ein breites Spektrum angeborener Fehlbildungen mit unterschiedlichster phänotypischer und klinischer Manifestation. Diagnostik und Betreuung der Patientinnen und Patienten erfordern viel Erfahrung und Expertise sowie die Anbindung an ein multidisziplinäres Behandlungsteam. Die operative Korrektur erfolgt meist im Kindes- und Jugendalter und ist daher seit Jahrzehnten eine Domäne der Kinder- und Jugendchirurgie.Eine operative Korrektur ist nur dann sinnvoll, wenn dadurch eine wesentliche Besserung der Symptomatik erzielt werden kann. Bei weniger schwerwiegenden Deformitäten oder auch in Grenzfällen ist zunächst ein konservatives Vorgehen bestehend aus gezielter Physiotherapie und Anwendung entsprechender Orthesen ratsam. Bei Ausbleiben des gewünschten Therapieerfolgs oder wenn die Betroffenen einer konservativen Therapie gänzlich ablehnend gegenüberstehen, ist die nächste Behandlungsoption die Operation. Hier haben sich hauptsächlich die minimal-invasiven Vorgehensweisen durchgesetzt, da diese mit kürzerer Operationsdauer, früherer Mobilisierung, besserem und stabilerem postoperativen Ergebnis und geringerem Narbenbildungsrisiko einhergehen.Zusammenfassend lässt sich also festhalten, dass zahlreiche an den jeweiligen Schweregrad der Deformierung angepasste Therapiekonzepte für angeborene Thoraxdeformitäten existieren. Sobald ein Wunsch nach Behandlung besteht bzw. körperliche Beschwerden in Erscheinung treten, ist die Anbindung jener Patientinnen und Patienten an ein Spezialzentrum mit auf diese Fehlbildungen spezialisierten Kinder- und Jugendchirurgen und -chirurginnen empfohlen. Dort können diese Patientinnen und Patienten entsprechend den neuesten wissenschaftlichen und operativen Standards und größtmöglicher fachlicher Expertise betreut werden.
Static analysis for discovering IoT vulnerabilities
Authors: Ferrara Pietro , Mandal Amit Kr , Cortesi Agostino , Spoto Fausto 
Published: November 2020

AbstractThe Open Web Application Security Project (OWASP), released the “OWASP Top 10 Internet of Things 2018” list of the high-priority security vulnerabilities for IoT systems. The diversity of these vulnerabilities poses a great challenge toward development of a robust solution for their detection and mitigation. In this paper, we discuss the relationship between these vulnerabilities and the ones listed by OWASP Top 10 (focused on Web applications rather than IoT systems), how these vulnerabilities can actually be exploited, and in which cases static analysis can help in preventing them. Then, we present an extension of an industrial analyzer (Julia) that already covers five out of the top seven vulnerabilities of OWASP Top 10, and we discuss which IoT Top 10 vulnerabilities might be detected by the existing analyses or their extension. The experimental results present the application of some existing Julia’s analyses and their extension to IoT systems, showing its effectiveness of the analysis of some representative case studies.
Videogame Addiction Scale for Children: Psychometric Properties and Gamer Profiles in the Italian Context
Authors: Monacis Lucia , Griffiths Mark D. , Cassibba Rosalinda , Sinatra Maria , Musso Pasquale 
Published: November 2020

AbstractGiven the few studies examining the evaluation of screening tools for videogame addiction among children aged 12 years and under, the present study analyzed (i) the psychometric properties (factorial structure, reliability indices and criterion validity) of the Italian version of the Videogame Addiction Scale for Children (VASC) and (ii) its construct validity using a person-centered approach. Two studies were carried out. In study 1, 728 participants completed a survey including demographic information, questions concerning the amount of time spent in playing videogames, and the Italian version of the VASC. In study 2, 1008 participants completed a survey comprising demographic information, the Italian version of the VASC, the Big Five Questionnaire for Children, and the social dimension subscale of the Multidimensional Self-Concept Scale. Findings supported (i) the four-dimensional first-order factor structure, (ii) full scalar invariance across age groups and partial scalar equivalence across gender, and (iii) reliability and criterion validity of the VASC. The construct validity of the VASC was confirmed by the identification of two distinct profiles (high videogame players vs. low videogame players) and their specific patterns of associations with personality traits and social self-concept. Interaction effects of gender × profiles on personality traits were evidenced. Overall, the findings provided validity for the use of the Italian version of the VASC and extending the body of literature on videogame addiction.
News repertoires and information behavior in Austria—What is the role of social inequality?
Authors: Prandner Dimitri , Glatz Christoph 
Published: November 2020

AbstractThe changes in the global mediascape have had a tremendous impact on societal news flows. Using data from the Social Survey Austria 2018 and a quantitative application of the media repertoire approach, the article illustrates how information behavior and news seeking relate to social status, political orientation and sociodemographics. The results confirm that the developments in Austria—often referred to as a representative of a traditional media landscape—are mostly in line with international trends, as new media have been added to the media repertoires of approximately two-thirds of the sample. Effects tied to social inequality generally match previous assumptions: Higher educational achievements and income lead to more diversified news repertoires. Additionally, the overall structure of the data indicates that the online-only users are still a small minority, consisting of younger individuals who are less likely to work and more likely to vote for left-wing parties.
In-process calibration of smart structures produced by incremental forming
Authors: Al-Baradoni Nassr , Krech Martin , Groche Peter 
Published: November 2020

AbstractSmart load-bearing structures are created by forming integration of functional materials into passive metallic components with target-oriented pre-stress conditions by rotary swaging. Their sensory capability cannot only be used during the utilization but also during the manufacturing phase. Previous works demonstrated how this capability paves the way for efficient monitoring and controlling of the used integration process. In search of an even higher overall efficiency of the manufacturing chain, the subsequent costly calibration step deserves closer attention. Therefore, a cost- and time-efficient approach for the process-integrated calibration of a sensor-integrated structure is proposed in this paper. During the in-process calibration, the acting process forces are measured both in the integrated sensor and in a special-built clamping fixture. The measured data can be transferred into calibration slopes of the sensory structures. A suitable signal processing based on the process characteristics is performed to compensate interference effects on the raw signals. As a result, an accuracy of the calibration better than 2% of the nominal value compared to an offline standardized calibration is achieved with the in-line calibration method. Consequently, efficiency in the manufacturing of sensory structures is further boosted by avoidance of setup or logistical operations.
New Approaches to Critical Illness Polyneuromyopathy: High-Resolution Neuromuscular Ultrasound Characteristics and Cytokine Profiling
Authors: Fisse Anna Lena , May Caroline , Motte Jeremias , Pedreiturria Xiomara , Breuer Thomas G. K. , Schneider-Gold Christiane , Marcus Katrin , Gold Ralf , Yoon Min-Suk , Pitarokoili Kalliopi 
Published: November 2020

AbstractBackgroundDiagnosis of intensive care unit acquired weakness (ICUAW) is challenging. Pathogenesis of underlying critical illness polyneuromyopathy (CIPNM) remains incompletely understood. This exploratory study investigated whether longitudinal neuromuscular ultrasound examinations and cytokine analyses in correlation to classical clinical and electrophysiological assessment contribute to the understanding of CIPNM.MethodsIntensive care unit patients were examined every 7 days until discharge from hospital. Clinical status, nerve conduction studies, electromyography as well as ultrasound of peripheral nerves and tibial anterior muscle were performed. Cytokine levels were analyzed by a bead-based multiplex assay system.ResultsOf 248 screened patients, 35 patients were included at median of 6 days (IQR: 8) after admission to intensive care unit. Axonal damage was the main feature of CIPNM. At the peak of CIPNM (7 days after inclusion), nerve ultrasound showed cross-sectional area increase of tibial nerve as a sign of inflammatory edema as well as hypoechoic nerves as a possible sign of inflammation. Cytokine analyses showed signs of monocyte and macrophage activation at this stage. Fourteen days after inclusion, cytokines indicated systemic immune response as well as profiles associated to neovascularization and regeneration.ConclusionsExploratory neuromuscular ultrasound and cytokine analyses showed signs of inflammation like macrophage and monocyte activation at the peak of CIPNM followed by a systemic immune response parallel to axonal damage. This underlines the role of both axonal damage and inflammation in pathogenesis of CIPNM.
Optimal progressivity of personal income tax: a general equilibrium evaluation for Spain
Authors: Serrano-Puente Darío 
Published: November 2020

AbstractIs the Spanish economy positioned at its optimal progressivity level in personal income tax? This article quantifies the aggregate, distributional, and welfare consequences of moving toward such an optimal level. A heterogeneous households general equilibrium model featuring both life cycle and dynastic elements is calibrated to replicate some characteristics of the Spanish economy and used to evaluate potential reforms of the tax system. The findings suggest that increasing progressivity would be optimal, even though it would involve an efficiency loss. The optimal reform of the tax schedule would reduce wealth and income inequality at the cost of negative effects on capital, labor, and output. Finally, these theoretical results are evaluated using tax microdata and describe a current scenario where the income-top households typically face suboptimal effective average tax rates.
A novel anti-slip control approach for railway vehicles with traction based on adhesion estimation with swarm intelligence
Authors: Zirek Abdulkadir , Onat Altan 
Published: November 2020

AbstractAnti-slip control systems are essential for railway vehicle systems with traction. In order to propose an effective anti-slip control system, adhesion information between wheel and rail can be useful. However, direct measurement or observation of adhesion condition for a railway vehicle in operation is quite demanding. Therefore, a proportional–integral controller, which operates simultaneously with a recently proposed swarm intelligence-based adhesion estimation algorithm, is proposed in this study. This approach provides determination of the adhesion optimum on the adhesion-slip curve so that a reference slip value for the controller can be determined according to the adhesion conditions between wheel and rail. To validate the methodology, a tram wheel test stand with an independently rotating wheel, which is a model of some low floor trams produced in Czechia, is considered. Results reveal that this new approach is more effective than a conventional controller without adhesion condition estimation.
Source Apportionment and Elemental Composition of Atmospheric Total Suspended Particulates (TSP) Over the Red Sea Coast of Saudi Arabia
Authors: Cusack M. , Arrieta J. M. , Duarte C. M. 
Published: November 2020

AbstractThis work presents a comprehensive study on concentrations and elemental composition of total suspended atmospheric particulates for a semi-urban site on the Red Sea coast, and on-board a research vessel, which collected off-shore samples along the Red Sea. We conducted one of the most extended measurement campaigns of atmospheric particulates ever for the region, with continuous measurements over 27 months. The overall mean concentrations (± st. dev.) of TSP were 125 ± 197 µg m−3 for the permanent semi-urban site, and 108 ± 193 µg m−3 for the off-shore mobile site. The region is frequently severely impacted by both localised and widespread dust storms, which on occasion, can increase atmospheric particulate concentrations to levels above mg m−3 (> 1000 µg m−3). Median concentrations were not as variable between seasons, indicating a stable, permanent presence of atmospheric particulates independent of the time of year. The primary chemical elements contributing to particulate mass were Na, Ca, S, Al and Fe. We employed Positive Matrix Factorisation (EPA PMF v5.0.14) to identify different major sources of particulates, which were crustal, marine, fuel oil combustion/secondary sulphate and mixed anthropogenic. The crustal source was characterised by tracers Al, Fe, K, Mg and Sn, and was present to some extent in the other identified sources due to the permanent presence of dust particles in the atmosphere. The fuel oil combustion/secondary sulphate source was identifiable by the almost exclusive presence of S, and to a lesser extent V, emitted from oil combustion as primary emissions and also secondary sulphate formation following the release of S to the atmosphere. A mixed anthropogenic source was characterised by Zn, Ni, Cr, Cu and Pb, emitted from traffic, industry, power generation and water desalination. This study highlights that the natural sources of particulates in this desert region give rise to frequent episodes of extremely poor air quality, and this problem is compounded by significant emissions of anthropogenic pollution, which has an impact across the entire Red Sea basin. Further stringent measures should be adopted to improve air quality across the region and prevent long-term damage to the health of the local population and ecosystems.
Nachbetreuung von PatientInnen mit „sustained virologic response“
Authors: Semmler Georg , Mandorfer Mattias 
Published: November 2020

ZusammenfassungDa die Therapie der chronischen Hepatitis C aufgrund der neuen direkt antiviral wirkenden Therapeutika („direct-acting antivirals“, DAA) aus virologischer Sicht bei nahezu allen PatientInnen zur nachhaltigen Ausheilung („sustained virologic response“, SVR) der Infektion führt, hat sich das Hauptaugenmerk auf Eliminationsprojekte sowie die Nachsorge von PatientInnen mit ausgeheilter Hepatitis-C-Infektion verschoben. In diesem Übersichtsartikel werden rezente Studien und Empfehlungen zum Thema Nachsorge nach HCV-Eradikation zusammengefasst, um den LeserInnen einen Leitfaden für die klinische Praxis zur Verfügung zu stellen.
Social stigma, ego‐resilience, and depressive symptoms in adolescent school dropouts
Authors: Kwon Taeyeon 
Published: November 2020

ABSTRACTIntroductionAdolescent dropouts experience various psychosocial difficulties such as social stigma, depressive symptoms, and anxiety after they leave school. This study examined the longitudinal effects of social stigma on depressive symptoms, and the mediating effects of ego‐resilience in the relationship between these two variables among South Korean adolescent dropouts aged 14 to 19.MethodsThis study utilized four waves of data from the Out of School Panel Survey (N = 278), assessed annually from 2013 to 2017, which were analyzed using latent growth curve modeling.ResultsBoth social stigma and depressive symptoms showed positive linear growth over time, while ego‐resilience showed negative linear growth. The increase in social stigma was associated with an increase in depressive symptoms and a decrease in ego‐resilience. Initial levels of ego‐resilience mediated the relationship between the initial levels of social stigma and depressive symptoms. Moreover, changes in ego‐resilience mediated the relationship between changes in social stigma and depressive symptoms.ConclusionsThese findings highlight the need for tailored interventions and strategies for preventing depressive symptoms and building ego‐resilience to help dropouts overcome social stigma.
APPLYING STATE SPACE MODELS TO STOCHASTIC CLAIMS RESERVING
Authors: Hendrych Radek , Cipra Tomas 
Published: November 2020

AbstractThe paper solves the loss reserving problem using Kalman recursions in linear statespace models. In particular, if one orders claims data from run-off triangles to time series with missing observations, then state space formulation can be applied for projections or interpolations of IBNR (Incurred But Not Reported) reserves. Namely, outputs of the corresponding Kalman recursion algorithms for missing or future observations can be taken as the IBNR projections. In particular, by means of such recursive procedures one can perform effectively simulations in order to estimate numerically the distribution of IBNR claims which may be very useful in terms of setting and/or monitoring of prudency level of loss reserves. Moreover, one can generalize this approach to the multivariate case of several dependent run-off triangles for correlated business lines and the outliers in claims data can be also treated effectively in this way. Results of a numerical study for several sets of claims data (univariate and multivariate ones) are presented.
Statistical risk warnings in gambling
Authors: NEWALL PHILIP W.S. , WALASEK LUKASZ , HASSANNIAKALAGER ARMAN , RUSSELL ALEX M.T. , LUDVIG ELLIOT A. , BROWNE MATTHEW 
Published: November 2020

AbstractGambling is considered a public health issue by many researchers, similarly to alcohol or obesity. Statistical risk warnings on gambling products can be considered a public health intervention that encourages safer gambling while preserving freedom of consumer choice. Statistical risk warnings may be useful to gamblers, given that net gambling losses are the primary driver of harm and that gambling products vary greatly in the degree to which they facilitate losses. However, there is some doubt as to whether statistical risk warnings are, in their current form, effective at reducing gambling harm. Here, we consider current applications and evidence, discuss product-specific issues around a range of gambling products and suggest future directions. Our primary recommendation is that current statistical risk warnings can be improved and also applied to a wider range of gambling products. Such an approach should help consumers to make more informed judgements and potentially encourage gambling operators to compete more directly on the relative ‘price’ of gambling products.