bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vertebral Column Decancellation for Correcting Cervicothoracic Kyphotic Deformity in Patients With Ankylosing Spondylitis
Authors: Yu Han , Wang Qi , Fan Yiming , Qi Dengbin , Wang Tianhao , Li Bing , Huang Yi , Wang Ze , Xue Chao , Zheng Guoquan 
Published: December 2024

ABSTRACTObjectiveSurgery to correct the cervicothoracic kyphotic deformity in ankylosing spondylitis (AS) can be associated with serious neurovascular risks. According to the literature, there are no clinical reports documenting the use of vertebral column decancellation (VCD) in the treatment of cervicothoracic kyphotic deformity in patients with AS. The purpose of the present study was to retrospectively analyze and evaluate the effect of VCD on cervicothoracic kyphotic deformity in patients with AS.MethodsRecords of eight patients with cervicothoracic kyphotic deformity who underwent VCD at C7 in our institution were retrospectively reviewed. The mean duration of clinical follow‐up after surgery was 19 months. The cervical lordosis (CL) and C2–C7 sagittal vertical axis (SVA) were meticulously measured on full‐length spine radiographs. The chin‐brow vertical angle (CBVA) was measured on clinical photographs. Outcome measures utilized included the Neck Disability Index (NDI), the Japanese Orthopaedic Association (JOA) Score, and a Visual Analog Scale (VAS) for neck pain. The data analysis was performed using SPSS version 26.0 for Windows. For paired data adhering to a normal distribution, we utilized paired sample t‐tests to analyze preoperative and postoperative imaging parameters. Statistical significance was established at a p value threshold of < 0.01.ResultsAll eight patients successfully completed the surgery. With an average VCD osteotomy angle of 47.6° ± 8.1° (±SD), the mean preoperative CBVA was 81.1° ± 17.6° (±SD), while the immediate postoperative value was 19.9° ± 5.7° (±SD). The overall average correction was 61.2° ± 18.9°. The mean preoperative cervical sagittal imbalance was 93.4 ± 27.3 mm (±SD), while the immediate postoperative value was 40.2 ± 18.9 mm (±SD). The overall average correction was 53.2 ± 28.1 mm. None of the eight patients experienced intraoperative complications, including nerve or vascular injury, cerebrospinal fluid leakage, or any other related complications. In the cohort of eight patients, the mean values for estimated blood loss, surgical time, and hospital stay were 1313 mL, 248 min, and 18 days, respectively. In comparison to preoperative scores, statistically significant improvement was noted in all patients in the postoperative period with regard to NDI, JOA, and VAS (p < 0.01, using a paired t‐test).ConclusionThe VCD procedure proves to be a dependable and efficient approach for addressing cervicothoracic kyphotic deformities. It achieves remarkable corrections in cervical kyphosis and CBVA.Trial RegistrationChinese Clinical Trial Registry: 2400090375
Association Between Food Allergy Status and Atopic Dermatitis Control and Persistence: A Longitudinal Analysis of the Pediatric Eczema Elective Registry
Authors: Wong Jessica J. , Margolis David J. 
Published: December 2024

ABSTRACTAtopic dermatitis (AD) and food allergies (FA) are closely linked manifestations of atopic disease, sharing immunological pathways that contribute to their chronicity and mutual exacerbation. However, the long‐term impact of FA on AD remains incompletely understood. To address this knowledge gap, we analyzed 8015 children from the Pediatric Eczema Elective Registry (PEER), exploring the relationship between FA status as an exposure and AD control as an outcome at enrollment, as well as AD persistence as another outcome over 10 years. Our results indicate that at enrollment, children with any FA had significantly higher odds of having uncontrolled AD, and over the course of 10 years, they were more likely to experience persistent AD compared to those without any FA. These associations were particularly pronounced in subgroup analyses of milk, egg, and peanut allergies, highlighting the importance of recognizing FA as a significant prognostic factor in managing long‐term AD outcomes in comorbid cases.
Primary large B‐cell lymphoma of the central nervous system: A reappraisal of CD5‐positive cases based on clinical, pathological, and molecular evaluation
Authors: Yamada Seiji , Satou Akira , Tsuyuki Yuta , Iba Sachiko , Okumura Yuka , Ishikawa Eri , Ito Hideaki , Kogure Yasunori , Goto Naoe , Tanikawa Motoki , Shimada Kazuyuki , Tsukamoto Tetsuya , Karube Kennosuke , Yokoo Hideaki , Kataoka Keisuke , Tomita Akihiro , Mase Mitsuhito , Nakamura Shigeo 
Published: December 2024

AbstractCD5 expression is seen in 5%–10% of de novo diffuse large B‐cell lymphomas (DLBCLs). Primary large B‐cell lymphoma of the central nervous system (PCNS‐LBCL) also exhibits CD5 expression in a minority of cases, however, clinicopathological and molecular features remain largely unclarified. Here we present the clinical, molecular, and pathological features of 11 CD5‐positive (+) PCNS‐LBCL cases, occupying 6.7% of all 165 PCNS‐LBCLs diagnosed in our institutions. While CD5+ systemic DLBCL has been recognized as a distinctive subgroup showing an aggressive clinical course, no obvious differences were found between CD5+ and CD5‐negative subgroups among the present CNS patients clinically. MYD88 p.L265P and CD79B p.Y196 mutations were detected in eight (73%) and seven (64%) cases, respectively, supporting previous reports. Notably, the microenvironmental immune cells were universally PD‐L1/CD274‐positive, and the higher levels tended to present favorable overall survival, as already evidenced in the PCNS‐LBCL series. In contrast, neoplastic PD‐L1/CD274 expression was undetectable in all cases. Indeed, no structural variations or copy number alterations involving PD‐1 ligands were detected by targeted‐capture sequencing and fluorescence in situ hybridization. While further studies are warranted, we may have confirmed similarity between PCNS‐LBCLs and intravascular large B‐cell lymphomas from a molecular standpoint.
Sustainable coffee leaf rust management: The role of soil covering, conditioners and controlled‐release fertilizers
Authors: Resende Laís Sousa , Vilela Marina Scalioni , Pozza Edson Ampélio , Castanheira Dalyse Toledo , Voltolini Giovani B. , da Silva Larissa Cocato , Botrel Élberis Pereira , Diotto Adriano Valentim 
Published: December 2024

AbstractSustainable soil management to optimize water use and enhance nutrient uptake is a promising approach for decreasing the incidence of coffee leaf rust. This work analysed soil coverings, fertilizers and soil conditioners to optimize water usage and nutrients in coffee rust management. The experiment was set up in the field in January 2016, with seedlings of Coffea arabica ‘Mundo Novo IAC – 379‐19’, susceptible to rust. The experimental design was in randomized blocks with three replications and arranged in a 3 × 2 × 5 factorial scheme. We assessed the combination of three soil coverings (plastic film, Urochloa decumbens and bare soil), two fertilizer types (conventional and controlled release) and five soil conditioners (organic compound, coffee husk, agricultural gypsum, water‐retaining polymer and control without soil conditioner). The rust incidence and foliage progress curve were integrated into the area under the rust incidence or foliage progress curve. Additionally, we assessed the leaf area index and coffee yield. The association of U. decumbens with controlled‐release fertilizers and organic compound or coffee husk increased coffee foliage and yield despite higher disease incidence.
SlTCP29 and SlTCP24 participate in the morphological development of tomato compound leaves by integrating multiple pathways
Authors: Bi Mengxi , Wang Zhijun , Cheng Keyan , Meng Sida , Qi Mingfang 
Published: December 2024

AbstractLeaves are the primary vegetative organs of plants, and their morphology is an important trait affecting plant architecture, light energy utilization, environmental adaptation, and fruit quality and yield. Leaf development is highly flexible; however, understanding the regulatory mechanisms of factors coordinating leaf morphogenesis and differentiation remains limited. In this study, we obtained a double mutant for SlTCP29 and SlTCP24 genes from the CRISPR/Cas9 mutant population, both belonging to the CINCINNATA‐like TCP (TEOSINTE BRANCHED, CYCLOIDEA and PCF1/2) transcription factor subfamily. Simultaneous mutations of SlTCP29 and SlTCP24 genes increase the complexity of tomato leaves, characterized by deeper leaf margin notches and increased number of leaflets. In conjunction with RNA‐seq analysis, determination of plant hormone content, and molecular interaction assays, we identified the KNOXII gene SlTKNII5, SlMIR164a, and 1‐aminocyclopropane‐1‐carboxylic acid synthase gene SlACS1A as direct downstream targets of SlTCP29 and SlTCP24, among which SlTKNII5 can physically interact with other KNOXII members to form heterodimers. Our study provides insight into the mechanisms by which SlTCP29 and SlTCP24 are involved in the morphological development of tomato compound leaves by integrating multiple pathways, including transcription factor, microRNA, and phytohormone.
Grafting with non‐suckering rootstock increases drought tolerance in Corylus avellana L. through physiological and biochemical adjustments
Authors: Moine Amedeo , Chitarra Walter , Nerva Luca , Agliassa Chiara , Gambino Giorgio , Secchi Francesca , Pagliarani Chiara , Boccacci Paolo 
Published: December 2024

AbstractPhysiological and molecular mechanisms underpinning plant water stress responses still need deeper investigation. Particularly, the analysis of rootstock‐mediated signals represents a complex research field, offering potential applicative perspectives for improving the adaptation of fruit crops to environmental stresses. Nonetheless, fundamental knowledge on this subject needs to be widened, especially in some woody species, including European hazelnut (Corylus avellana L).To fill these gaps, we inspected dynamic changes in gas exchanges and stem water potential of two hazelnut genotypes, the ‘San Giovanni’ cultivar (SG), the non‐suckering rootstock ‘Dundee’ (D), and their heterograft (SG/D), during a drought stress treatment followed by recovery. Biometric and anatomical traits were measured at the beginning and end of water stress imposition. Additionally, differences in abscisic acid and proline contents were analysed in leaves and roots taken from well‐irrigated, stressed and recovered plants, in combination with expression profiles of candidate genes.Grafting with ‘Dundee’ rootstock positively affected the ability of ‘San Giovanni’ plants to endure drought by increasing their intrinsic water use efficiency and facilitating post‐rehydration recovery. Although anatomical adjustments occurred, we showed that the improved stress adaptation of grafted plants rather depended on biochemical modifications, resulting in increased root proline concentrations and leaf ABA accumulation both during water stress and recovery. We also proved that those metabolic changes were controlled by a differential reprogramming of genes involved in hormone metabolism and stress defence.Grafting with non‐suckering rootstocks could therefore represent a promising and environmentally‐friendly strategy for improving the adaptability of hazelnut to water deficit.
Family function and depression in older adults with chronic comorbidities: the chain‐mediated role of cognitive fusion and coping styles
Authors: Jiao‐Mei Xue , Yang Li‐Hui , Sun Fei‐Fei , Su Jing 
Published: December 2024

AbstractBackgroundThis study explores the influence of family function on depression in older adults with chronic comorbidities and the mediating roles of cognitive fusion and coping styles.MethodsThe Family Adaptation Partnership Growth Affection and Resolve Index, Patient Health Questionnaire‐9, Cognitive Fusion Questionnaire‐Fusion, and Trait Coping Style Questionnaire were used to survey 448 community‐dwelling older adults with chronic comorbidities. A mediation test was conducted using the Process 4.0 macro program.ResultsFamily function was found to be significantly and negatively correlated with cognitive fusion, maladaptive coping style, and depression. Cognitive fusion and maladaptive coping style were positively correlated with depression. Cognitive fusion was positively correlated with maladaptive coping styles. Family function affected depression directly; it also affected older adults' depression through two indirect paths: through the mediating role of cognitive fusion and the chain‐mediating role of both cognitive fusion and maladaptive coping style.ConclusionsFamily function in older adults can influence their levels of depression, which is mediated by cognitive fusion and maladaptive coping styles. Based on these findings, interventions to prevent and alleviate depression in older adults with chronic disease comorbidities can be offered to improve their well‐being.
Governance and global collaboration in non‐democratic countries
Authors: Ali Hamid E. 
Published: December 2024

AbstractThe concept of good governance (GG) has emerged from the corridors of global institutions, influencing changes, particularly in non‐democratic countries. This paper uses both qualitative and quantitative approaches to address the following question: To what extent does global collaboration (GC) impact governance in non‐democratic countries? The paper incorporates proxies for GC, more deeply exploring the dynamics and frameworks that link GC and governance. The GC variables measuring institutional globalization have a positive impact on governance, while global openness and information globalization have a negative impact. These mixed results invite further research on governance and GC. However, the national visions can set the stage for future agendas that combine partnership, collaboration, transparency, and innovation to achieve GG.
Associations between dyadic language style matching and classroom observations of behaviorally inhibited children's sociability
Authors: Sem Kathy , Shakiba Nila , Rubin Kenneth H. , Novick Danielle R. , Druskin Lindsay R. , Smith Kelly , Danko Christina M. , Chronis‐Tuscano Andrea , Wagner Nicholas J. 
Published: December 2024

AbstractChildren's sociability, the motivation and ability to initiate and maintain social interactions, influences how children navigate their social worlds. When sociability supports interactions, it contributes to social competence and positive social‐emotional outcomes. Although a substantial body of literature characterizes how specific parenting behaviors have an early and lasting influence on children's social development, far fewer studies have considered how characteristics of, and interactions within the parent‐child dyad influence children's sociability. For example, matching affect and behaviors during dyadic interactions may provide insight into children's openness to affiliate, and these interactions provide opportunities to model and practice responses to behavioral and emotional cues common in social interactions. One novel approach to characterizing behavioral matching in dyadic interactions is language style matching (LSM), a linguistic construct characterizing the similarity of subconscious speech patterns (i.e., function words) between members of dyads during social interaction. Although researchers have established links between LSM and other characteristics of the dyad known to influence children's social development (e.g., attachment quality), whether and how LSM predicts children's adaptive sociability among peers is currently unknown. Therefore, we examined the associations between parent‐child LSM and classroom observations of children's sociability among 151 preschoolers with elevated behavioral inhibition. Results indicated that LSM is positively associated with observed sociability in the company of classmates over and above other aspects of the parent‐child relationship (e.g., parenting). Results supported LSM as an indicator of behavioral matching and contributed to the growing body of research that considers the implications of LSM for children's social development.
State‐Crafted Dominant Fictions: How Bad Documents, Gut Feelings, and Selective Intelligence Shape Border Control in Europe
Authors: Lindberg Annika , Borrelli Lisa Marie 
Published: December 2024

ABSTRACTThis article details how knowledge is produced, circulated, and acted upon by migration control officials working in different sites of the European border regime. Drawing on research into the politics of knowledge in border and migration control, along with studies of street‐level bureaucracy, we trace the knowledge mobilised to craft state fictions that form the basis of border bureaucrats' decision‐making. Empirically, the article builds on research carried out in three different projects that all explore how borders are enacted across Europe and beyond. It details how knowledge is produced at the rear and frontline of border and migration control, and traces how ‘bad documents’, gut feelings, and informal administrative practices informed by racialized and class‐based suspicions are mobilised for decision‐making. Sources matter less in such state‐crafted dominant fictions, which instead obtain their legitimacy through bureaucratic circulation and inscription and make them ‘true enough’ for officials to act upon.
Party digitalization and website features: a comparative study of party organizations
Authors: Lisi Marco 
Published: December 2024

AbstractThe emergence of new digital tools has brought about a revolution in party organizations. However, the literature is still lacking comparative studies that utilize comprehensive theoretical frameworks and consider variations in the supply‐side of party digitalization. This paper addresses both shortcomings by turning the spotlight on party websites. By relying on data from the Political Party Database, we delve into the determinants of website functionalities across a spectrum of diverse political parties. Our findings underscore that parties with less centralized leadership and affiliated to the left of the ideological spectrum tend to display websites with a broader range of functions. Moreover, younger parties also tend to present more complex websites, although this effect is mitigated by their electoral strength. Notably, a common thread among most parties is the use of their websites for mobilizing human and financial resources, while interactive features remain less prevalent.
Evolution and Driving Mechanisms of the Integrated Development of Traditional and New Infrastructure: Evidence From China
Authors: Pan Yaru , Long Limin , Wang Yingdong 
Published: December 2024

ABSTRACTPromoting the integration of traditional and new infrastructure to establish a coordinated modern infrastructure system is crucial for promoting high‐quality economic development. Using provincial‐level panel data, this study employs the entropy method, coupling coordination degree model, and spatial econometric models to investigate spatial–temporal trends and driving mechanisms of the integrated development of traditional and new infrastructure in China from 2008 to 2020. The findings reveal that while the overall development level of China's traditional and new infrastructure has steadily improved, it remains relatively low. Second, the integrated development of traditional and new infrastructure remains in the middle‐ and low‐integration stages. Third, spatial analysis highlights a significant positive correlation in integrated development across regions, forming a semi‐enclosed spatial distribution pattern. Finally, urbanization, informatization, industrial structure, government management, and technological innovation are important mechanisms driving the integrated development of traditional and new infrastructure. Our research provides a foundation for policies aimed at advancing infrastructure integration and fostering regional economic coordination.
Comparison of laboratory‐based and non‐laboratory‐based cardiovascular risk prediction tools in rural India
Authors: Birhanu Mulugeta Molla , Zengin Ayse , Evans Roger G. , Kim Joosup , Olaiya Muideen T. , Riddell Michael A. , Kalyanram Kartik , Kartik Kamakshi , Suresh Oduru , Thomas Nihal , Srikanth Velandai K. , Thrift Amanda G. 
Published: December 2024

AbstractBackgroundNon‐laboratory‐based cardiovascular risk prediction tools are feasible alternatives to laboratory‐based tools in low‐ and middle‐income countries. However, their effectiveness compared to their laboratory‐based counterparts has not been adequately tested.AimWe compared estimates from laboratory‐based and non‐laboratory‐based risk prediction tools in a low‐ and middle‐income country setting.MethodsUsing a cross‐sectional design, residents of the Rishi Valley region, Andhra Pradesh, India, were surveyed from 2012 to 2015. Ten‐year absolute risk was compared for laboratory‐based and non‐laboratory‐based Framingham Risk Score (FRS), World Health Organization‐Risk Score (WHO‐RS) and risk prediction tool for global populations (Globorisk). An agreement was assessed using ordinary least‐products (OLP) regression (for RS) and quadratic weighted kappa (κw, for risk band).ResultsAmong 2847 participants aged 40–74 years, the mean age was 54.0 years. Cardiovascular RS increased with age and was greater in men than women in each age group. For all tools, regardless of whether laboratory or non‐laboratory‐based, over 80% of the participants were classified in the same risk band. There was strong agreement between laboratory‐based and non‐laboratory‐based tools, greatest for the WHO‐RS tools (OLP slope = 0.96, κw = 0.93) and least for the FRS (OLP slope = 0.84, κw = 0.88). The level of agreement was greater among women than men, less in those with hypercholesterolaemia or hypertension than those without, and was particularly poor among those with diabetes.ConclusionsNon‐laboratory‐based Framingham, WHO‐RS and Globorisk tools performed relatively well compared with their laboratory‐based counterparts in rural India. However, they may be less useful for risk stratification when applied to individuals with diabetes.
How Do Scientists Think? Contributions Toward a Cognitive Science of Science
Authors: Nersessian Nancy J. 
Published: December 2024

AbstractScientific thinking is one of the most creative expressions of human cognition. This paper discusses my research contributions to the cognitive science of science. I have advanced the position that data on the cognitive practices of scientists drawn from extensive research into archival records of historical science or collected in extended ethnographic studies of contemporary science can provide valuable insight into the nature of scientific cognition and its relation to cognition in ordinary contexts. I focus on contributions of my research on analogy, model‐based reasoning, and conceptual change and on how scientists enhance their natural cognitive capacities by creating modeling environments that integrate cognitive, social, material, and cultural resources. I provide an outline of my trajectory from a physicist to a philosopher of science to a hybrid cognitive scientist in my quest to understand the nature of scientific thinking.