bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of the financial cycle on the economic cycle and the regulatory role of monetary policy: evidence from China
Authors: Yuan Xinxin , Liu Kefu 
Published: December 2024

PurposeFirst, we explored the dynamic relationship between the economic and financial cycles under a unified endogenous framework. There is less literature on the relationship between the financial cycle and the economic cycle endogenously under a unified framework. Our research helps to fill the gap in this area. Second, there is no conclusive evidence on whether the monetary policy framework should take the financial cycle into account. Our findings provide a clear answer and a useful reference for the practice of monetary policy in other countries.Design/methodology/approachWe incorporate the financial cycle equation based on the traditional new Keynesian model to construct a new Keynesian four-equation model that includes financial factors and further explores the dynamic relationship between the economic cycle and the financial cycle under a unified endogenous framework. We choose the three-stage least squares (3SLS) method for the estimation of the model. Then we utilize a time-varying parameter vector autoregression (TVP-SV-VAR) model incorporating stochastic volatility to explore the mechanism of the dynamic association between the financial cycle and monetary policy in China.FindingsFirst, we explored the relationship between the economic cycle and the financial cycle. The results show that the financial cycle has a significant positive impact on the economic cycle, but the economic cycle has a limited effect on the financial cycle. Then, we examine the linkage mechanism between China’s economic cycle, financial cycle and monetary policy. The results show that the response of China’s monetary policy to economic cycle shocks and financial cycle shocks is more significant. Moreover, monetary policy is giving higher and higher weight to the financial cycle.Originality/valueFirst, we constructed a new Keynesian four-equation model incorporating financial factors to explore the dynamic relationship between the economic and financial cycles under a unified endogenous framework. There is less literature on the relationship between the financial cycle and the economic cycle endogenously under a unified framework. Our research helps to fill the gap in this area. Second, there is no conclusive evidence on whether the monetary policy framework should take the financial cycle into account. Our findings provide a clear answer and a useful reference for the practice of monetary policy in other countries.
Stakeholders’ perception of sustainable ecotourism development – an explorative study on Dooars region of West Bengal, India
Authors: Chanda Ishita , Sajnani Manohar , Gowreesunkar Vanessaa G.B. 
Published: December 2024

PurposeThis study evaluated various stakeholders’ knowledge and awareness of ecotourism development in the Dooars region to understand the local community’s attitudes and provide critical information on the influence of ecotourism and how sustainable development can be carried out in the region.Design/methodology/approachA quantitative methodology was used to evaluate the link between awareness and the need for education among stakeholders and local communities for the growth of ecotourism.FindingsWe found that the educated locals had a favorable attitude toward the effects of ecotourism and were supportive of its expansion. They had a more favorable opinion of improving facilities, image and infrastructure, promoting the region as an ecotourism destination, and preserving the environment compared with the less educated locals in the field of research.Originality/valueThe social, cultural and ecological advantages of ecotourism are seen to have a fairly high level of correlation with awareness of those benefits, while the social, cultural and environmental benefits of ecotourism are seen to have an adequate level of positive correlation with knowledge of ecotourism. In this instance, participants’ awareness of ecotourism’s advantages and views of their ecotourism expertise both grow as they see the sociocultural and environmental impact of ecotourism.
The guardian of local culture: the dynamic of Indonesian local television to survive against global media onslaught
Authors: Haryono Cosmas Gatot , Bungin Burhan , Teguh Monika 
Published: December 2024

Purpose
The idea of television as a space for cultural and local wisdom has been enthusiastically welcomed by many parties. Regrettably, this expectation proves to be nothing more than an empty hope. Indonesian national television rarely broadcasts content with local cultural nuances. National television broadcast is filled with popular and global cultural content. Only local television tries hard to remain the last guardian of Indonesian culture and local wisdom. Several studies have raised the issue of local television broadcast content but have not succeeded in explaining the dynamics that occur in the management of local television to maintain and inherit local culture. This study aims to fill this gap.

Design/methodology/approach
This research was conducted using a qualitative descriptive method with interview techniques as data collection methods.

Findings
Indonesian local television continues to struggle to become the guardian for the sustainability of Indonesian local culture by emphasizing its market segmentation and trying to meet their needs, trying hard to implement intensification and extensification strategies, continuing to struggle to balance the onslaught of global culture and relying on government agencies as a nice market. However, the role and support of the government are greatly needed. Without it, local television will surely fall.

Originality/value
This research reflects the dynamics that occur in the management of local television which is very challenging. By revealing the struggles that local television goes through in fortifying local culture and the minimal role of the Indonesian government, this research contributes to the development of sustainable strategies and the inheritance of local culture in this global era.
Missing investment protection rules in India’s new free trade agreements: towards decoupling
Authors: Ranjan Prabhash 
Published: December 2024

Purpose
This paper aims to show that India is decoupling its international investment law obligations from its international trade law obligations. This decoupling goes beyond the split between investment protection rules and trade agreements. If investment protection rules are missing from the trade agreement, it is a case of partial decoupling. If India does not legalize its investment relations with a country with whom it has signed a free trade agreement (FTA), either within or outside the trade agreement, it becomes a case of complete decoupling.

Design/methodology/approach
This paper follows doctrinal methodology. It compares India’s past FTA practice with the new one to show the dissimilarity between India’s FTA 1.0 and 2.0.

Findings
India’s new FTAs differ from the FTAs signed in the 2000s. Unlike the previous FTAs, the new ones do not contain investment protection rules. India is indulging in decoupling because it wants to de-legalize its international investment relations to exercise greater control over foreign investment. The paper concludes by observing that as India’s fundamental reason for signing FTAs is to be part of global value chains, it should consider including investment protection rules within its trade agreements.

Originality/value
No research yet compares India’s past FTAs with the new ones to show that investment protection is no longer part of India’s trade agreement practice.
Experimental method for creating skin with acquired appendage dysfunction
Authors: Moriwaki Yuta , Shiraishi Makoto , Shen Qi , Du Zening , Okazaki Mutsumi , Kurita Masakazu 
Published: December 2024

AbstractMammalian skin appendages, such as hair follicles and sweat glands, are essential for both esthetic and functional purposes. Conditions such as burns and ulcers can lead to dysfunction or loss of skin appendages and result in hair loss and dry skin, posing challenges in their regeneration. Existing animal models are insufficient for studying acquired dysfunction of skin appendages without underlying genetic causes. This study aimed to develop more clinically relevant mouse models by evaluating two approaches: keratinocyte transplantation and grafting of skin at varying thicknesses. green fluorescent protein (GFP)‐expressing keratinocytes were transplanted into ulcers on nude mice, leading to re‐epithelialization with minimal skin appendages at 4 weeks after transplantation. However, the re‐epithelialized area was largely derived from recipient cells, with the grafted cells contributing to only 1.31% of the area. In the skin‐grafting model, donor skin from GFP transgenic mice was grafted onto nude mice at three thicknesses: full thickness, 10/1000 inch, and 5/1000 inch. The grafted area of the 5/1000‐inch grafts remained stable at 89.5% of its original size 5 weeks after transplantation, ensuring a sufficiently large skin area. The 5/1000‐inch grafts resulted in a significant reduction in skin appendages, with a mean of only 3.73 hair follicles per 5 mm, compared with 69.7 in the control group. The 5/1000‐inch skin grafting in orthotopic autologous transplantation also showed the achievement of skin surfaces with a minimal number of skin appendages. Therefore, a mouse model with skin grafting demonstrated stability in producing large areas of skin with minimal appendages. In conclusion, these two models with acquired skin appendage dysfunction and no underlying genetic causes provide valuable tools for researching skin appendage regeneration, offering insights into potential therapeutic strategies for conditions involving skin appendage loss.
Intrinsic and extrinsic factors influencing Bacillus cereus spore inactivation in spices and herbs: Thermal and non‐thermal sterilization approaches
Authors: Leishangthem Chinglen , Mujumdar A. S. , Xiao Hong‐Wei , Sutar P. P. 
Published: December 2024

AbstractThe presence of Bacillus cereus in spices and herbs has posed a detrimental effect on food safety. The absence of thorough testing, comprehensive reporting, and vigilant surveillance of the illness has resulted in a significant underestimation of the true prevalence of foodborne illness caused by B. cereus. B. cereus spores are resistant to thermal processing (superheated steam, microwave, radiofrequency, infrared) that remains a significant challenge for the spice industry. Non‐thermal techniques, such as cold plasma, gamma irradiation, and electron beam irradiation, have gained significant interest for their ability to inactivate B. cereus spores. However, these technologies are constrained by inherent limitations. The composition of B. cereus spores, including dipicolinic acid, divalent cations, and low water content in the core, contributes significantly to their resistance properties. This review delves into the different factors that impact B. cereus spores in spices and herbs during sterilization, considering both intrinsic and extrinsic factors. This review also discussed the various techniques for inactivating B. cereus spores from spices and highlighted their effectiveness and constraints. It also provides valuable insights for enhancing sterilization strategies in the spices and herbs industry.
Date palm (Phoenix dactylifera) bioactive constituents and their applications as natural multifunctional ingredients in health‐promoting foods and nutraceuticals: A comprehensive review
Authors: Alu'datt Muhammad H. , Rababah Taha , Tranchant Carole C. , Al‐u'datt Doa'a , Gammoh Sana , Alrosan Mohammad , Bani‐Melhem Khalid , Aldughpassi Ahmed , Alkandari Dina , AbuJalban Dana 
Published: December 2024

AbstractFoods that support human health and longevity are becoming increasingly relevant as substitutes for or adjuncts to pharmacological drugs, either through direct consumption or incorporation into designer foods fortified with health‐promoting ingredients. Date palm (Phoenix dactylifera L.) fruits, seeds, and pollen are a cornerstone of diverse food and medicine traditions. Their reported metabolic activities include anti‐inflammatory, antioxidant, antihypertensive, antihyperlipidemic, antidiabetic, antitumor, antianemia, hepatoprotective, antibacterial, and antiviral effects. Beneficial effects on gut health and vascular health, as well as effectiveness in alleviating certain dysfunctions of the reproductive system, have also been noted. The genomic diversity of this versatile tree and the diverse agroecological conditions in which it grows lead to appreciable variations in the occurrence of protective nutrients and other high‐value bioactive phytochemicals, including flavonoid and non‐flavonoid phenolics, carotenoids, phytosterols, and oxylipins, whose potential remains underutilized in the food sector. As food ingredients, date fruits and their co‐products can improve the sensory, nutritional, and nutraceutical qualities of a broad range of dietary items. Their high nutritional density can assist with the design of novel or improved products that meet the demand for healthier foods. This review summarizes the current state of evidence on the potentialities of date palm fruits and co‐products in functional food development, focusing on the nutrients and extra‐nutritional compounds of interest, their biofunctional activities, and factors that influence their abundance and bioactivity. Proofs of concept across food and beverage categories, new developments, and clinical evidence are discussed, followed by recommendations for addressing research gaps.
Ultrasonographic Evaluation of Urate Crystal Deposition in Tendons With Gout Patients
Authors: Deng Si‐Hui , Wang Jie , Hu Jing , Tu Bin , Dang Wan‐Tai , Liu Jian 
Published: December 2024

ABSTRACTObjectiveTo use ultrasound technology to assess the deposition of urate crystals in the common lower limb tendons of patients with gout, providing additional imaging information for the management of these patients.MethodsHigh‐frequency ultrasound was retrospectively used to evaluate urate crystal deposition in common lower limb tendons—quadriceps, patellar, and Achilles—in patients with gouty arthritis. Comparative statistical analysis was conducted among asymptomatic hyperuricemia patients and healthy individuals during the same period.ResultsAggregates were detected in the tendons of all three groups, whereas tophi were found exclusively in tendons of asymptomatic hyperuricemia and gout groups. The prevalence of intratendinous aggregates and tophi in gout was significantly higher than the other groups (p < 0.05). The Achilles tendon showed the highest involvement, followed by the quadriceps and patellar tendons.ConclusionTendons are common sites of urate deposition in patients with gout and asymptomatic hyperuricemia. Aggregates and tophi are frequently observed in and around large tendons such as the quadriceps, patellar, and Achilles tendons in gout patients. Ultrasonography proves useful in highly sensitive and specific evaluation of urate deposition within and around tendons.
Leveraging artificial intelligence to reduce diagnostic errors in emergency medicine: Challenges, opportunities, and future directions
Authors: Taylor R. Andrew , Sangal Rohit B. , Smith Moira E. , Haimovich Adrian D. , Rodman Adam , Iscoe Mark S. , Pavuluri Suresh K. , Rose Christian , Janke Alexander T. , Wright Donald S. , Socrates Vimig , Declan Arwen 
Published: December 2024

AbstractDiagnostic errors in health care pose significant risks to patient safety and are disturbingly common. In the emergency department (ED), the chaotic and high‐pressure environment increases the likelihood of these errors, as emergency clinicians must make rapid decisions with limited information, often under cognitive overload. Artificial intelligence (AI) offers promising solutions to improve diagnostic errors in three key areas: information gathering, clinical decision support (CDS), and feedback through quality improvement. AI can streamline the information‐gathering process by automating data retrieval, reducing cognitive load, and providing clinicians with essential patient details quickly. AI‐driven CDS systems enhance diagnostic decision making by offering real‐time insights, reducing cognitive biases, and prioritizing differential diagnoses. Furthermore, AI‐powered feedback loops can facilitate continuous learning and refinement of diagnostic processes by providing targeted education and outcome feedback to clinicians. By integrating AI into these areas, the potential for reducing diagnostic errors and improving patient safety in the ED is substantial. However, successfully implementing AI in the ED is challenging and complex. Developing, validating, and implementing AI as a safe, human‐centered ED tool requires thoughtful design and meticulous attention to ethical and practical considerations. Clinicians and patients must be integrated as key stakeholders across these processes. Ultimately, AI should be seen as a tool that assists clinicians by supporting better, faster decisions and thus enhances patient outcomes.
Completion Rate of Paper‐Based and Electronic Patient Reported Outcome Measures in a Multidisciplinary Cancer Survivorship Clinical Setting
Authors: Tan Sim Yee , Turner Jane , Kerin‐Ayres Kim , Hewitt Lynnette , Butler Sue , Deguchi Cole , Khatri Sonia , Wildbore Carolyn , Cunningham Ilona , Dhillon Haryana M. , Malalasekera Ashanya , Vardy Janette L. 
Published: December 2024

ABSTRACTObjectiveIntegrating Patient‐Reported Outcome Measures (PROMs) into clinical practice is increasing, with research showing benefits in patient outcomes. However, evidence regarding patient's acceptance of PROMs is limited. Sydney Cancer Survivorship Centre (SCSC) clinic is a multidisciplinary clinic where clinicians use PROMs to guide patient consultation. This study explored SCSC patient acceptability of PROMs in clinical care by evaluating PROMs' completion rates.MethodsThis retrospective audit of PROMs completion rates evaluates two periods: 1) September 2013–November 2019 (pre‐coronavirus disease 2019) and 2) October 2020–September 2023, following the implementation of electronic PROMs. Overall, 866 new patients attended SCSC during the two audit periods, with 822 (95%) giving consent for data to be included. Descriptive statistical methods were used to analyse completion rates.ResultsBetween September 2013 and November 2019 (audit period 1), 656 new survivors attended the SCSC clinic; 622 (95%) consented to data use. The highest completion rate for paper‐based PROMs was the food questionnaire (92%); with 91% for distress thermometer, symptoms, and exercise‐related PROMs; 85% for quality of life; 77% for self‐rated performance status, and 55.5% for a 3‐day food diary. From October 2020 to September 2023 (period 2), the response rate for PROMs was 99% (n = 198/200) for initial clinic attendees; and 92% for electronic PROMs (n = 169/184).ConclusionsUsing comprehensive PROMs in clinical care is feasible. The completion rate was high; similar between paper‐based and electronic PROMs. Comprehensive PROMs can guide clinical consultations. PROMs may improve communication between survivors and clinicians and enhance the quality of care.
Longitudinal correlation of cerebrospinal fluid GFAP and the progression of cognition decline in different clinical subtypes of Parkinson's disease
Authors: Liu Yumei , Wang Jing , Ning Fangbo , Wang Guojun , Xie Anmu 
Published: December 2024

AbstractGlial fibrillary acidic protein (GFAP) is an intermediate filament protein expressed mainly in astrocytes of the central nervous system (CNS), a potential biomarker of cognitive decline in Parkinson's disease (PD). The central motor subtypes of PD include tremor‐dominant (TD), postural instability and gait disorder (PIGD), and indeterminate subtypes, whose different course of disease requires the development of biomarkers that can predict progression based on motor subtypes. In this study, we aimed to assess the predictive value of cerebrospinal fluid (CSF) GFAP for PD motor subtypes in PD. Two hundred and sixteen PD patients were recruited in our study from the progression markers initiative. Patients were subgrouped into TD, PIGD, and indeterminate subtypes. Longitudinal relationships between baseline CSF GFAP and cognitive function and CSF biomarkers were assessed using linear mixed‐effects models. Cox regression was used to detect cognitive progression in TD patients. The baseline and longitudinal increases in CSF GFAP were associated with a greater decline in episodic memory, CSF α‐syn, and a greater increase of CSF NfL in TD and TD‐male subtypes. Cox regression showed that higher baseline CSF GFAP levels were corrected with a higher risk of developing mild cognitive impairment (MCI) over a 4‐year period in the PD with normal cognition (NC) group (adjusted HR = 1.607, 95% CI 1.907–2.354, p = 0.01). CSF GFAP might be a promising predictor of cognition decline in TD.
Right middle occipital gyrus is associated with egocentric spatial orientation during body tilt: Evidence from a repetitive transcranial magnetic stimulation study
Authors: Tani Keisuke , Naito Eiichi , Mizobe Koji , Hirose Satoshi 
Published: December 2024

AbstractAccurate perception of the orientation of external objects relative to the body, known as egocentric spatial orientation, is fundamental to performing action. Previously, we found via behavioural and magnetic resonance imaging voxel‐based morphometry studies that egocentric spatial orientation is strongly distorted when the whole body is tilted with respect to gravity, and that the magnitude of this perceptual distortion is correlated with the grey matter volume of the right middle occipital gyrus (rMOG). In the present study, we further validated the association between the neural processing in the rMOG and the perceptual distortion by transiently suppressing neural activity in this region using low‐frequency repetitive transcranial magnetic stimulation (rTMS) and evaluating the consequent effect on perceptual distortion. Our results showed that rTMS over the rMOG significantly reduced perceptual distortions when the body was tilted in the frontal plane, while it did not affect egocentric spatial orientation in the upright position. No significant changes in perceptual distortion were observed when rTMS was applied to another cortical candidate (the right temporo‐parietal junction). These results provide evidence that neural processing in the rMOG is associated with body tilt‐related perceptual distortion, suggesting that the rMOG may be engaged in egocentric spatial orientation related to gravitational information.