bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphology, genetic characterization and molecular phylogeny of pinworm Skrjabinema longicaudatum sp. n. (Oxyurida: Oxyuridae) from the endangered Tibetan antelope Pantholops hodgsonii (Abel) (Artiodactyla: Bovidae)
Authors: Cao Yi-Fan , Chen Hui-Xia , Li Yang , Zhou Dang-Wei , Chen Shi-Long , Li Liang 
Published: September 2020

Abstract
Background: The Tibetan antelope Pantholops hodgsonii (Abel) (Artiodactyla: Bovidae) is an endangered species of mammal endemic to the Qinghai-Tibetan Plateau. Parasites and parasitic diseases are considered to be important threats in the conservation of the Tibetan antelope. However, our present knowledge of the composition of the parasites from the Tibetan antelope remains limited. Methods: Large numbers of nematode parasites were collected from a dead Tibetan antelope. The morphology of these nematode specimens was observed using light and scanning electron microscopy. The nuclear and mitochondrial DNA sequences [i.e. small subunit ribosomal DNA (18S), large subunit ribosomal DNA (28S), internal transcribed spacer (ITS) and cytochrome c oxidase subunit 1 (cox1)] were amplified and sequenced for molecular identification. Moreover, phylogenetic analyses were performed using maximum likelihood (ML) inference based on 28S and 18S + 28S + cox1 sequence data, respectively, in order to clarify the systematic status of these nematodes.Results: Integrated morphological and genetic evidence reveals these nematode specimens to be a new species of pinworm Skrjabinema longicaudatum (Oxyurida: Oxyuridae). There was no intraspecific nucleotide variation between different individuals of S. longicaudatum sp. n. in the partial 18S, 28S, ITS and cox1 sequences. However, a high level of nucleotide divergence was revealed between the new species and its congeners in 28S (8.36%) and ITS (20.3–23.7%) regions, respectively. Molecular phylogenetic results suggest that the genus Skrjabinema should belong to the subfamily Oxyurinae (Oxyuroidea: Oxyuridae), instead of the subfamily Syphaciidae or Skrjabinemiinae in the traditional classification, as it formed a sister relationship to the genus Oxyuris. Conclusions: A new species of pinworm Skrjabinema longicaudatum sp. n. (Oxyurida: Oxyuridae) is described. Skrjabinema longicaudatum sp. n. represents the first species of Oxyurida (pinworm) and the fourth nematode species reported from the Tibetan antelope. Our results contribute to the knowledge of the species diversity of parasites from the Tibetan antelope, and clarify the systematic position of the genus Skrjabinema.
COVID-19 Outbreak and Acute Cholecystitis in a Hub Hospital in Milan: Wider Indications for Percutaneous Cholecystostomy.
Authors: Barabino Matteo , Piccolo Gaetano , Trizzino Arianna , Fedele Veronica , Ferrari Carlo , Nicastro Vincenzo , Ceretti Andrea Pisani , De Nicola Enrico , Mariani Nicolò Maria , Giovenzana Marco , Scifo Giovanna , Mazza Massimiliano , Vercelli Ruggero , Santambrogio Roberto , Luigiano Carmelo , Opocher Enrico 
Published: September 2020

Abstract
BACKGROUND.COVID-19 pandemic has impacted the Italian national health care system at many different levels, causing a complete reorganization of surgical wards. In this context, in this study we retrospectively analyzed our management strategy for patients with acute cholecystitis.METHODS.We analyzed all patients admitted to our Emergency Department for acute cholecystitis from February 27th to April 30th, 2020. We graded each case according to the 2018 Tokyo Guidelines. All patients were tested for positivity to SARS-CoV-2 and received an initial conservative treatment. RESULTS.Thirty-seven patients were admitted for acute cholecystitis (13 grade I, 16 grade II and 8 grade III). According to Tokyo Guidelines 2018, patients were successfully treated with antibiotic only, bedside percutaneous transhepatic gallbladder drainage and laparoscopic cholecystectomy in 29.7%, 21.6 % and 48.7% of cases respectively. Therapeutic strategy of three out of 8 cases, otherwise fit for surgery, submitted to percutaneous transhepatic gallbladder drainage (37.5%), were directly modified by COVID-19 pandemic: one due to the SARS-CoV-2 positivity, while two others due to unavailability of operating room and intensive care unit for post-operative monitoring respectively. Overall success rate of percutaneous drainage was of 87.5%, the mean post-procedural hospitalization length was 9 days, and no related adverse event were observed.CONCLUSIONS.Bedside cholecystostomy has shown to be an effective and safe treatment, which acquired an increased relevance in the present acute phase of the pandemic. This strategy will potentially be taken into consideration in future phases, when the coexistence with the virus will require us to respond in an even more virtuous fashion.
Trends and Determinants of Diarrhea Among Under-Five Children in Ethiopia: Cross-Sectional Study Design: Multivariate Decomposition and Multilevel Analysis Based on Bayesian Approach Evidenced by EDHS 2000-2016 Data.
Authors: Negesse Yilkal , Adimasu Asefa , Negesse Ayenew , Awoke Tadesse 
Published: September 2020

Abstract
Background: Despite significant progress in the reduction of under-five child deaths over the last decades in Ethiopia, still diarrhea remains the second cause of morbidity and mortality among under five children next to pneumonia. Objective: To show trends and determinants of diarrhea among under five children in Ethiopia based on the four Ethiopian Demographic and health surveys data (2000- 2016).Methods: Community-based cross-sectional study design was used. A total of 10753 in 2000, 10039 in 2005, 10946 in 2011 and 10337 in 2016 under five age children were involved. Multivariate decomposition and multilevel analysis based on Bayesian approach was performed.Results: Ninety seven percent of the change in diarrhea prevalence over time was attributable to difference in behavior. Being twin (AOR=1.3; 95% CrI 1.1-1.5), big weight (AOR=1.63; 95 % CrI 1.62–2.02), not vaccinated for rotavirus (AOR= 1.44; 95 % CrI 1.12–1.9) and for measles (AOR= 1.2; 95 % CrI 1.1–1.33), poor wealth status (AOR 2.6; 95 % CrI 1.7–4.06), having more than three under-five children(AOR 1.3; 95 % CrI 1.1–1.61), member of health insurance(AOR 2.2; 95 % CrI 1.3–3.8) and long distance from the health facility (AOR 2.7; 95 % CrI 2.2–3.5) were more likely to experience diarrhea. Conclusion: The prevalence of diarrhea was significantly declined over the last sixteen years and the decline was due to difference in coefficients between the surveys. Being twin , weight of child at birth, vaccinated for measles and rotavirus, number of under-five children, wealth status, distance to health facility, health insurance and child waste disposal method were significantly associated with diarrhea among under five children in Ethiopia. Therefore Ethiopian government should primarily focus on the strengthening and scaling up of behavioral change packages to prevent diarrheal disease.
Perception Data Fusion of Agricultural Products Supply Chain Based on Internet of Things
Authors: Sun Xu , Shu Kunliang 
Published: September 2020

Abstract
With the continuous development of the logistics industry and big data technology, the integration of traditional industries and the Internet of Things has become the trend of the times. However, agricultural product quality problems occur from time to time in multiple links such as the production and circulation of agricultural products. Therefore, the agricultural product supply chain based on the Internet of Things has gradually received attention. The purpose of this paper is to study the application of perception data fusion of agricultural products supply chain based on internet of things. In order to study the application of perception data fusion of agricultural products supply chain based on Internet of things, this paper analyzes the status quo of agricultural products industry traceability platform and extracts other product supply modes based on the Internet of things technology. After analysis and comparison, it comes to the perception data fusion mode suitable for the agricultural product supply chain, and uses the information technology based on the internet of things to carry out the agricultural product circulation process Internet of things transformation and process optimization. The results show that the application of data fusion based on the internet of things can solve 69.45% of the agricultural products whose origins are unknown and cannot be traced, improve the supply efficiency of agricultural products by 43%, reduce the health problems of agricultural products by 31.24%, reduce the prices of agricultural products by 13%-20%, improve the logistics efficiency and save about 5 million tons of agricultural products. Therefore, it is necessary to study the application of agricultural product perception data fusion based on internet of things.
Clinical Characteristics and Prognostic Factors in Pediatric Vascular Tumors
Authors: Rujkijyanont Piya , Traivaree Chanchai , Supakul Nucharin , Satayasoontorn Kantang , Photia Apichat , Monsereenusorn Chalinee 
Published: September 2020

Abstract
Background: Vascular tumor is a specific entity of vascular anomalies with variable clinical manifestations and outcomes. Although surgical intervention is the gold standard to establish diagnosis and treatment, the procedure also carries certain risk especially in cases with large and inoperable tumors. Determinant factors to predict clinical outcomes among those patients were not well studied. The study aimed to explore clinical characteristics including investigational and treatment approaches as well as associated prognostic factors of vascular tumors specifically in pediatric populations. Methods: Pediatric patients with confirmed diagnosis of vascular tumors between January 1, 2005 and December 31, 2017 were enrolled in this study. Clinical data including initial clinical manifestations with associated complications, diagnostic studies used to establish diagnosis, treatment modalities provided and final outcomes were retrospectively reviewed and analyzed. Results: In all, 50 patients with confirmed diagnosis of vascular tumors were enrolled. The median age at diagnosis was 11.5 years with equal gender distribution. The most common type of vascular tumors was hemangioma (n=41, 82%), followed by pyogenic granuloma (n=4, 8%), kapasiform hemangioendothelioma with Kasabach-Merritt phenomenon (n=2, 4%), infantile hepatic hemangioma (n=2, 4%) and juvenile nasal angiofibroma (n=1, 2%). The median age at diagnosis among patients with cutaneous vascular tumors (12.4 years) was significantly older than the age of those with visceral vascular tumors (1.3 years) with p-value of 0.009. The mean size among patients with visceral tumors (7.46±4.84 cms) was significantly greater than the size among patients with cutaneous tumors (3.21±3.7 cms) with p-value of 0.023. Size of the tumor was the only independent risk factor associated with clinical outcomes.Conclusion: Clinical characteristics of vascular tumors are heterogenous. Diagnosis can be made using clinical manifestations combined with radiological and histopathological examination. Treatment approaches consist of close observation, medications and surgery. Clinical outcomes are favorable among most patients and size of the tumor is an independent risk factor associated with outcomes. This study was registered at www.clinicaltrials.in.th under the title, “Vascular tumors in pediatric hematology-oncology settings” with registration number: TCTR20190917001.
Bias Estimation In Study Design: A Meta-Epidemiological Analysis of Transcatheter Versus Surgical Aortic Valve Replacement
Authors: Youn Saerom , Wong Shannon Avery , Chrystoja Caitlin , Tomlinson George , Wijeysundera Harindra C , Bell Chaim M , Gagliardi Anna R , Baxter Nancy N , Sandhu Lakhir , Takata Julie , Urbach David Robert 
Published: September 2020

Abstract
Objective: To estimate the bias associated with specific nonrandomized study attributes among studies comparing transcatheter aortic valve implantation with surgical aortic valve replacement for the treatment of severe aortic stenosis.Data sources and study selection: We searched 7 databases from inception to June 2017: Medline, Medline In-Process/ePubs, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Scopus, and Web of Science. We included all RCTs and nonrandomized studies that reported outcomes of interest.Data extraction and synthesis: We categorized studies according to study design, and evaluated 41 nonrandomized study attributes as potential sources of bias. We calculated odds ratios (OR) and other effect measures with 95% confidence intervals (CI) using random effects models.Main outcomes: One month postoperative mortality, and length of stay. Bias was defined as the difference in estimates of treatment effects between nonrandomized studies and high quality (low risk of bias) RCTs, which were considered to provide “gold standard” estimates.Results: We included 6 RCTs and 87 nonrandomized studies. Surgical risk scores were similar for comparison groups in RCTs, but were higher for patients having transcatheter aortic valve implantation in nonrandomized studies. Nonrandomized studies underestimated the benefit of transcatheter aortic valve implantation compared with RCTs. For example, nonrandomized studies without adjustment estimated a higher risk of postoperative mortality for transcatheter aortic valve implantation compared with surgical aortic valve replacement (OR 1.43 [95% CI, 1.26 to 1.62]) than high quality RCTs (OR 0.78 [95% CI, 0.54 to 1.11). Nonrandomized studies using propensity score matching (OR 1.13 [95% CI, 0.85 to 1.52]) and regression modelling (OR 0.68 [95% CI, 0.57 to 0.81]) to adjust results estimated treatment effects closer to high quality RCTs. Nonrandomized studies describing losses to follow-up estimated treatment effects that were significantly closer to high quality RCT than nonrandomized studies that did not.Conclusion: Studies with different attributes produce different estimates of treatment effects. Study design attributes related to the completeness of follow-up may explain biased treatment estimates in nonrandomized studies, as in the case of aortic valve replacement where high-risk patients were preferentially selected for the newer (transcatheter) procedure.
Classic Cardiovascular Risk Factors improve in Very Elderly Hypopituitary Patients Treated on Standard Hormone Replacement in Long Term Follow- Up.
Authors: Rosa Isabella Naves , Soares Alexandre Anderson de Souza Munhoz , Rodrigues Marcelo Palmeira , Naves Luciana Ansaneli 
Published: September 2020

Abstract
BackgroundHypopituitarism in the elderly population is an underdiagnosed condition and may increase comorbidities related to glucose metabolism, dyslipidemia, and cardiovascular risk factors. Optimization of hormone replacement take into account alterations in clearence rates of hormones, interaction with other medications, and evaluation of the risk-benefit ratio of treatment is a big challenge for clinical practice. ObjectivesThis study aimed to evaluate classic cardiovascular risk factors in hypopituitary septuagenarians and octagenarians by diagnosis and after long-term hormone replacement.MethodsThis is a retrospective observational study, and patients were recruited and selected from a registry in a tertiary medical center. We included patients aged from 70-99 years with hypopituitarism, evaluated hormonal and biochemical parameters, cardiovascular risk scores were calculated by diagnosis and compared after long-term follow-up. All patients signed informed consent. Patients' data were compared to a sex and age-matched control group, with long-term geriatric follow up, without endocrine diseases.ResultsThirty-five patients were included, 16 patients aged 70-75 years (72.61), 12 patients 76-80 years (72.28), 7 patients 81-99 years (89.28). Pituitary macroadenomas were the main cause of hypopituitarism, mean maximal diameter 3.4 cm (2.9- 4.3), and invasive craniopharyngiomas. At the moment of diagnosis, most patients were overweight, and abdominal adiposity was observed in 76.9% of women and 36.4% of men, mostly in octagenarians and nonagenarians. Co-morbidities were frequent, 85.7% presented Hypertension, 37.1% Diabetes, 53.1% low HDL, 51.5% hypertriglyceridemia. Most patients presented more than two combined pituitary deficiencies, hypogonadism in 88.6%, central hypothyroidism 82.9%, GH deficiency in 65.7%, and adrenal insufficiency in 25.7%. Analysis of cardiovascular risk prediction in the total cohort showed that 57.1% of patients presented a reduction in the General Cardiovascular Disease (CVD) Risk Prediction Score and 45.7% in atherosclerotic CVD risk estimated by ACC/AHA 2013 Pooled Cohort Equation, despite being submitted to conventional hormone replacement, during the meantime follow up pf 14.5 years. This reduction was not observed in the control group.Discussion and ConclusionIn this study, aged hypopituitary patients presented a reduction in estimated general CVD risk during long-term follow-up, despite replacement with corticosteroids, levothyroxine, or gonadal steroids. The early diagnosis and treatment of hypopituitarism in the elderly remain challenging. Larger studies should be performed to assess the risk-benefit ratio of hormone replacement in the metabolic profile in septuagenarian and octogenarian patients.
High-Q Spectral Peaks and Nonstationarity in the Geomagnetic Field Over the 400-4000 μHz Band
Authors: Chave Alan , Thomson David J , Luther Douglas , Riegert David 
Published: September 2020

Abstract
This paper analyzes three 60 d sections of geomagnetic data from Honolulu Observatory during 2001 − 2, showing the ubiquitous presence of narrowband, very statistically significant, high Q features in multitaper power spectra, along with pervasive nonstationarity as measured by the frequency offset coherence over 400 − 4000 µHz (or 2500 − 250 s period). This behavior is nearly identical in the H and Z components of the geomagnetic field, and more subdued in the much weaker D component. The peak frequencies correlate well with the optically − measured frequencies of solar p − modes, and the raw Qs are defined by the resolution bandwidths of the estimates, with values ranging from hundreds to thousands. Further, spectral peaks are consistently coherent across frequency due to nonstationarity, and frequently exhibit cyclostationarity at offset frequencies of ± 0.5 cycles per day. None of these characteristics are consistent with internal magnetospheric processes. A mixture central/noncentral chi square model was fit to raw spectral estimates in an attempt to model narrowband, high Q, quasi − deterministic modes embedded in a stochastic background. This model yielded noncentral fractions of 0.13 (1000 − 2000 µHz), 0.24 (1500 − 2500 µHz), 0.35 (2000 − 3000 µHz), 0.30 (2500 − 3500 µHz) and 0.17 (3000 − 4000 µHz). These values suggest that up to 35% of the power in the geomagnetic field in the 1000 − 4000 µHz band averaged over 60 days is forced by solar p − modes.
Physical Activity Counseling Received Throughout Pregnancy: Effect on Behaviors: A Quasi-experimental Study.
Authors: RUART Shelly , SINNAPAH Stéphane , HUE Olivier , JANKY Eustase , ANTOINE-JONVILLE Sophie 
Published: September 2020

Abstract
Background: Pregnant women declare perceived barriers to physical activity. Although physical activity is not often dispensed, effective counseling by health professionals is recommended. Health professionals training has been proposed as a target to improve physical activity effective counseling. The objective was to evaluate the physical activity counseling of trained and untrained health professionals given to pregnant women and the effect on the women’s physical activity behaviors.Methods: In a quasi-experimental trial, 72 pregnant women were allocated to a control or intervention group. Physical activity counseling was dispensed to the women in the intervention group by trained healthcare providers throughout pregnancy. The women in the control group followed the usual consultations. The counseling and physical activity levels were evaluated by Chi2 tests and repeated measures ANOVAs respectively.Results: Overall, the women received little counseling in accordance with the recommendations, although the intervention group women received it more frequently (p=0.049). All women who received counseling throughout pregnancy limited their decline in physical activity more than the others. The decline in sports activity among normal-weight pregnant women was reduced in the intervention group (p=0.032), and sedentary activity was preserved among the pre-pregnancy overweight women (p=0.027). The total quantity of physical activity was not different in women who received counseling in accordance with recommendations compared with that of the others.Conclusion: Our intervention showed the effectiveness of counseling on physical activity behaviors, although the effect was limited. Training for professionals should be strengthened to ensure that counseling in line with the recommendations is provided throughout pregnancy.Pregnant women should be encouraged to engage in physical activity from the beginning of pregnancy.Trial registration: The database for this study was retrospectively registered under No. MR 5815250919.
The Kumtag Meteorite Strewn Field
Authors: Du Ke , Li Shijie , Leya Ingo , Smith Thomas , Zhang Dongliang , Wang Peng 
Published: September 2020

Abstract
The Kumtag meteorite strewn field was found in the Kumtag desert, 132 kilometers south of Hami city in the Xinjiang province, China. It is an ellipse of 2.5×7.9 km, with a long axis extending along the northeast-southwest direction. The largest individual meteorite of the strewn field weights about 10 kg; the smallest individual has as mass of only 27 g. In total more than 100 individuals with a total mass of more than 180 kg were collected. The Kumtag meteoroid entered the atmosphere in the direction Northeast-Southwest. All meteorites collected in this strewn field are samples from the same unique meteorite shower. The Kumtag meteorite is an H5 ordinary chondrite with a shock stage S2, and a weathering grade W2. The cosmic ray exposure age of Kumtag is 6.7± 0.8 Ma, which is rather typical for H chondrites and which indicates that Kumtag was derived from the massive impact event on its parent body ~7 Ma ago. A significant He amount has been released during certain unknown processe(s) before the Kumtag meteorite was ejected from its parent body.