bluuebunny/crossref_metadata_2025_split huggingface dataset:
The distribution indices of erythrocytes: which one for acute ischemic stroke?
Authors: Ekici Günay Nahide , Günay Nurullah 
Published: November 2019

Abstract

Background
The erythrocytes distribution indices are reported from same histogram but they have different reference intervals and calculated by distinct measurements.

Objectives
To explore whether the RDW-CV and RDW-SD values may predictive and prognostic significance in ischemic stroke patients and to clarify the relation each of these indices with stroke severity and 3-months survival.

Materials and methods
Cumulative survival rates were calculated with the Kaplan-Meier method, and life curves were compared to RDW-CV, RDW-SD quartiles. The risk factors were described with a multivariable cox proportional hazard model.

Results
In acute ischemic stroke, RDW-CV was more specific and RDW-SD was more sensitive (92% vs. 80%) (52% vs. 48%). RDW-CV values higher than 14.7% are associated with 11-fold increase in the risk of stroke; and the level of RDW-CV does show a linear relationship with the severity of stroke. However, when we evaluated RDW-SD, higher 43.55 fL RDW-SD values was have 16-fold increase in severity of stroke and have a relatively high linear relationship with stroke severity scores to RDW-CV.

Conclusions
RDW-CV and RDW-SD levels have different prognostic poor outcomes for interpreting in ischemic stroke events approach and these should be used alone and comparatively with the AIS predictive and prognostic approach.
Sweat Loss and Fluid Intake of Female Varsity Ice Hockey Players During On-Ice Practices and Games
Authors: Bigg Jessica L. , Gamble Alexander S.D. , Vermeulen Tyler F. , Bigg Lindsey M. , Spriet Lawrence L. 
Published: November 2019

Abstract
Bigg, JL, Gamble, ASD, Vermeulen, TF, Bigg, LM, and Spriet, LL. Sweat loss and fluid intake of female varsity ice hockey players during on-ice practices and games. J Strength Cond Res 34(2): 389–395, 2020—Sweat losses of ∼1.5–2% body mass (BM) during exercise impairs athletic performance in stop and go sports such as ice hockey. The study examined the pre-exercise hydration status, sweat loss, fluid and carbohydrate (CHO) intake, and sodium balance of female hockey players. Twenty-four female varsity hockey players were tested during 2 practices and 4 games. Data analyses were performed using a level of significance of p ≤ 0.05. Over 70% of players arrived at the practices and ∼50% of players arrived at the game mildly dehydrated. Before the high- (P1) and low-intensity (P2) practices, players consumed an average of 0.19 ± 0.14 and 0.15 ± 0.13 L. Before the games, mean fluid intake was 0.39 ± 0.19 L. The sweat rate during P1 was significantly greater than P2 (p = 0.006), but there was no significant difference in total fluid intake between practices (p = 0.279). Consequently, the average BM loss for P1 was significantly greater than that for P2 (p = 0.016). Sweat loss during games was 1.01 ± 0.29 L and fluid intake was 0.70 ± 0.43 L, resulting in minimal BM losses (<1% BM for all players). CHO intake during games was 39.2 ± 22.8 g, with 19/20 players consuming CHO before or during the intermissions of the game. Sweat sodium losses were 0.64 ± 0.34 and 0.32 ± 0.18 g·h−1 for P1 and P2, and 0.83 ± 0.38 g during the game. In conclusion, female ice hockey players replaced the fluid they lost through sweat during practices and games and maintained adequate hydration. Players also consumed adequate CHO during games from the CHO containing food and drinks provided.
Effects of Seasonal Training Load on Performance and Illness Symptoms in Water Polo
Authors: Brisola Gabriel M.P. , Claus Gabriel M. , Dutra Yago M. , Malta Elvis S. , de Poli Rodrigo A.B. , Esco Michael R. , Zagatto Alessandro M. 
Published: November 2019

Abstract
Brisola, GMP, Claus, GM, Dutra, YM, Malta, ES, de Poli, RAB, Esco, MR, and Zagatto, AM. Effects of seasonal training load on performance and illness symptoms in water polo. J Strength Cond Res 34(2): 406–413, 2020—The purpose of the study was to describe the training load distribution of a young female water polo team in different cycles of the season and verify its subsequent effects on specific fitness measured by the repeated sprints ability (RSA) test, aerobic endurance measured by the lactate minimum test, incidence and severity of upper respiratory tract infection (URTI) symptoms, and muscle damage markers. The training load (i.e., rating of perceived exertion × session duration) of 20 young female water polo players (mean ± SD: age = 15.65 ± 1.3 years; body mass = 60.93 ± 11.0 kg; height = 1.62 ± 0.1 m) was monitored, and the incidence and severity of URTI was assessed during part of the season. In addition, we assessed the lactate minimum speed (LMS), RSA, creatine kinase (CK), and lactate dehydrogenase (LDH) blood concentration during the season. The level of significance set was p < 0.05. The training loads were higher in the specific period (p < 0.01), whereas a high incidence of URTI was observed in the general cycle. The LMS was greater in the general cycle (p < 0.05), whereas total time and best time in the RSA test were greater in the competitive cycle (p < 0.05). The CK and LDH concentrations were significantly lower during the competitive cycle (p < 0.01). The general cycle of a female water polo team is critical regarding URTI and muscle damage, even with smaller training loads than the specific period.
Examination of Significant Binder Aging Due to the Use of Different Anti-Stripping Additives in Polymer and CRM Asphalt Mixtures Using GPC
Authors: Kim Sungun , Kim Yeongsam , Kim Kwang W. 
Published: November 2019

Abstract
As an anti-stripping agent (ASA), hydrated lime (HL) has been widely used for many years in the world. Many brands of liquid-type ASA (LA), which properly provided the anti-stripping function, have been also developed and marketed. Because HL was found to provide anti-aging function of the binder in the mix, in addition to anti-stripping function, its use was known to have many advantages of other beneficial functions to the asphalt pavement. However, because the anti-aging function of LA is in question, it will be important to recognize if the anti-aging function is presented by the LAs too. Therefore, this study investigated the anti-aging effect of HL and three LAs in normal, crumb rubber–modified and polymer-modified asphalt mixes, in terms of absolute viscosity (AV) estimated from the large molecular size (LMS) measured by gel permeation chromatography (GPC), a scientific equipment. It was found that HL provided a significant retardation of age hardening, compared with the binder of the mix without any ASA. However, unlikely the anti-stripping function, most of the LAs did not show age retardation effect. The anti-aging function of liquid additives was not proved in this study, and therefore, the significant difference in binder aging was present due to the use of different ASA.
Visualization and Explainable Machine Learning for Efficient Manufacturing and System Operations
Authors: Le Dy D. , Pham Vung , Nguyen Huyen N. , Dang Tommy 
Published: November 2019

AbstractTo enable Industry 4.0 successfully, there is a need to build a resilient automation system that can quickly recover after having been attacked or robustly sustain continued operations while being threatened, enable an automated monitoring evolution via various sensor channels in real time, and use advanced machine learning and data analytics to formulate strategies to mitigate and eliminate faults, threats, and malicious attacks. It is envisioned that if we can develop an intelligent model that (a) represents a meaningful, realistic environment and complex entity containing manufacturing Internet of Things interdependent and independent properties that are stepping-stones of the cyber kill chain or precursors of the onset of cyberattacks; (b) can learn and predict potential errors and formulate offense/defense strategies and healing solutions; (c) can enable cognitive ability and human-in-the-loop analytics in real time; and (d) can facilitate system behavior changes to disrupt the attack cascade, then the hosting system can learn how to neutralize threats and attacks and self-repair infected or damaged links autonomously. In this article, our preliminary work presents a visual analytics framework and technique for situational awareness, including autonomously monitoring, diagnosing, and prognosticating the state of cyber-physical systems. Our approach, presented in this article, relies on visual characterizations of multivariate time series and real-time predictive analytics to highlight potential faults, threats, and malicious attacks. To validate the usefulness of our approach, we demonstrate the developed technique using various aviation datasets obtained from the Prognostics Center of Excellence at the National Aeronautics and Space Administration Ames.
Utilização de revestimento soldado para o aumento da vida útil de sulcadores em semeadoras adubadoras
Authors: Ferreira Mauro Fernando , Reis Ângelo Vieira dos , Machado Antônio Lilles Tavares 
Published: November 2019

Este trabalho teve o objetivo de verificar alternativa técnica e econômica para aumentar a vida útil das ponteiras de hastes sulcadoras de semeadoras adubadoras, através da adição de soldagem de revestimento em pontos estratégicos da ferramenta, aplicando-se material com quatro eletrodos revestidos e com arame tubular, nas direções longitudinal e transversal da superfície da ponteira. Os testes foram executados em solo franco-arenoso não mobilizado. O delineamento experimental foi inteiramente casualizado e para cada nível de desgaste foi feita a comparação das médias dos desgastes por análise de variância. O desgaste das ponteiras foi avaliado pela pesagem destas em intervalos de distância percorrida de 10,5 km até o limite de 52,5 km, quando a ponteira testemunha obteve o desgaste de 38,4% da massa inicial. Todas as soldagens aumentaram a vida útil da ponteira, sendo que o tratamento com arame tubular apresentou o melhor desempenho com menor custo.
Sequencing and Functional Annotation of the Whole Genome of Shiraia bambusicola
Authors: Ren Xiyi , Liu Yongxiang , Tan Yumei , Huang Yonghui , Liu Zuoyi , Jiang Xuanli 
Published: November 2019

Abstract
Shiraia bambusicola is a rare medicinal fungus found in China that causes bamboo plants to decay and die with severe infection. Hypocrellin, its main active ingredient, is widely used in several fields, such as medicine, agriculture, and food industry. In this study, to clarify the genomic components, taxonomic status, pathogenic genes, secondary metabolite synthesis pathways, and regulatory mechanisms of S. bambusicola, whole-genome sequencing, assembly, and functional annotation were performed using high-throughput sequencing and bioinformatics approaches. It was observed that S. bambusicola has 33 Mb genome size, 48.89% GC content, 333 scaffolds, 2590 contigs, 10,703 genes, 82 tRNAs, and 21 rRNAs. The total length of the repeat sequence is 2,151,640 bp. The annotation of 5945 proteins was obtained from InterProScan hits based on the Gene Ontology database. Phylogenetic analysis showed that S. bambusicola belongs to Shiraiaceae, a new family of Pleosporales. It was speculated that there are more than two species or genus in Shiraiaceae. According to the annotation, 777 secreted proteins were associated with virulence or detoxification, including 777 predicted by the PHI database, 776 by the CAZY and Fungal CytochromeP450 database, and 441 by the Proteases database. The 252 genes associated with the secondary metabolism of S. bambusicola were screened and enriched into 28 pathways, among which the terpenoids, staurosporine, aflatoxin, and folate synthesis pathways have not been reported in S. bambusicola. The T1PKS was the main gene cluster among the 28 secondary metabolite synthesis gene clusters in S. bambusicola. The analysis of the T3PKS gene cluster related to the synthesis of hypocrellin showed that there was some similarity between S. bambusicola and 10 other species of fungi; however, the similarity was very low wherein the highest similarity was 17%. The genomic information of S. bambusicola obtained in this study was valuable to understand its genetic function and pathogenicity. The genomic information revealed that several enzyme genes and secreted proteins might be related to their host interactions and pathogenicity. The annotation and analysis of its secondary metabolite synthesis genes and gene clusters will be an important reference for future studies on the biosynthesis and regulation mechanism of the secondary metabolites, contributing to the discovery of new metabolites and accelerating drug development and application.
Instrucción Ortopédica de Posgrado - Presentación
Authors: Ghisi Juan Pablo , Trache Adrián 
Published: November 2019

Se presenta el caso e imagenes de una paciente del sexo femenino de 26 años cuyo signo cardinal fue el engrosamiento de ambos tendones de Aquiles. Refiere haber comenzado aproximadamente a los 14 años con dolor y tumefacción de ambos tobillos que ella recuerda como de presentación aguda. Además, aparecieron -o incrementaron su tamaño- otros nódulos en manos y codos. We discuss the case and the radiological findings of a 26-year-old woman whose chief complaint was thickening of both Achilles tendons. She reports that the pain and swelling in both ankles suddenly started when she was about 14 years old. The patient also presents with new, or enlarged, nodules in the hands and elbows.
Errores de osteosíntesis en fracturas laterales de cadera tratadas con placa/tornillo deslizante [Osteosynthesis pitfalls in lateral hip fractures treated with plate / sliding screw system].
Authors: Pesciallo César Ángel , Pérez Alamino Leonel , Garabano Germán , Del Sel Hernán 
Published: November 2019

Introducción: El uso de los sistemas placa/tornillo deslizante para fracturas intertrocantéricas ha demostrado ser un método de fijación eficaz, pero no está exento de fallas. El propósito de este estudio fue evaluar las causas de falla en los pacientes con fracturas laterales de cadera, tratados con placa/tornillo deslizante, puntualizando los defectos técnicos en la colocación.Materiales y Métodos: En nuestro centro, se trató a 177 pacientes por fractura lateral de cadera, a 151 de ellos se les practicó osteosíntesis con placa/tornillo deslizante. Se analizaron la adecuada reducción posoperatoria, la medición de la distancia punta a vértice, la posición del tornillo cefálico en la cabeza femoral y las posibles complicaciones.Resultados: La serie quedó conformada por 143 pacientes. El seguimiento promedio fue de 18 meses (rango 12-48). La tasa de fallas fue del 8,4% (n = 12): 7 (4,8%) por migración cefálica (cut-out) del tornillo proximal, 2 (1,4%) por migración medial (cut-through), 2 (1,4%) presentaron seudoartrosis y un caso (0,70%) de reducción inadecuada en varo. El porcentaje de una segunda operación fue del 7,7% (n = 11). La peor posición fue la superior/posterior con un 100% de migración (n = 4) (p <0,001, diferencia estadísticamente significativa).Conclusión: El posicionamiento superior/posterior del tornillo cefálico podría incrementar la posibilidad de migración y, en consecuencia, la tasa de falla del sistema. AbstractIntroduction: The use of Dynamic Hip/Sliding Screw (DHS) for intertrochanteric fractures has proven to be an effective fixation method, but it also has its failures.The purpose of this study was to evaluate the reason of failures in patients with lateral hip fractures that were treated with a DHS.Method:177 patients were treated in our center for lateral hip fracture. In 151 of them we used a DHS. The adequate postoperative reduction, the measurement of the tip-to-apex distance, the position of the cephalic screw in the femoral head and the possible complications were analyzed.Results: The series was made up of 143 patients. The average follow-up was 18 months (range 12-48). The failure rate was 8.4% (n = 12): 7 (4.8%) due to cephalic migration (cut-out) of the proximal screw, 2 (1.4%) due to medial migration (cut-through) , 2 (1.4%) presented pseudoarthrosis and one case (0.70%) of inadequate reduction in varus. The percentage of a second operation was 7.7% (n = 11). The worst position was the superior / posterior with 100% migration (n = 4) (p <0.001, statistically significant difference).Conclusion: The superior / posterior positioning of the head screw could increase the possibility of migration and, consequently, the failure rate of the system.
Institutional dilemmas and challenges in the territorial construction of peace
Authors: Restrepo Botero Dario I. , Peña Galeano Camilo A. 
Published: November 2019

Implementation of the peace accords signed by the Colombian government and the leadership of FARC-EP will have strong institutional constraints. The central dilemma of the integration of post-conflict territories to the nation is the following: Will the State be taken to the provinces, or will the State be built from below, through strong social participation and a lasting local institutional creation? Although the agreements signed are part of the centralist tradition of building the national State from the top, they also provide space for significant reforms that would deepen the decentralisation process. To contribute to the public debate on the "territorial and differentiated construction" of peace, this essay reflects on how to operate in the 170 municipalities prioritised for intervention and proposes a series of institutional reforms not foreseen in the agreements, which would facilitate territorial State-building.
YETİŞKİNLERDE NADİR BİR İLEUS NEDENİ: İNVAJİNASYON
Authors: ULUTAŞ Mehmet Eşref , ŞİMŞEK Gürcan , ŞAHİN Alpaslan 
Published: November 2019

ÖZET

İnvajinasyon
proksimal bir bağırsak segmentinin distal bağırsak segmenti içine girmesidir.
Genellikle çocuklarda karşımıza çıkan bir patoloji olmasına karşın erişkinde de
nadir de olsa karşılaşılmaktadır. Atipik klinik seyrinden dolayı bazı
hastalarda preop tanısı konulamayabilir. Başvuru anındaki en sık semptom karın
ağrısıdır. Tanısı preop olarak USG, BT ile konulabilir. Bunların içinde tanı
koyma oranı en yüksek olan radyolojik yöntem BT’dir. Tedavisi cerrahidir. İnce
bağırsak kaynaklı olanlarda malignite nadirdir. Ancak kolon kaynaklı
invajinasyonlarda malignite olasılığı
yüksek olduğu için rezeksiyon yapılırken dikkatli olunmalıdır. Bu yazıda
bahsedilen hasta acile ileus bulgularıyla başvurdu ve invajinasyon tanısı konuldu. Çekilen
abdomen tomografide ince bağırsak
kaynaklı olduğu saptandı ve hasta opere edildi.
Operasyonda jejenum duvarına fiske tümör tespit edildi ve redüksiyon
sonrasında rezeksiyon işlemi uygulandı. Postop takiplerinde komplikasyon olmadı
ve hasta taburcu edildi. Patoloji sonucunda malignite saptanmadı.

ABSTRACT

İntussusception
is the condition whereby proximal intestinal segment drawn into the distal
bowel segment. When this disease seen usually a in children, it is rarely seen
in adults. Some patients may not have preop diagnosis due to atypical clinical
picture. The most common symptom is abdominal pain. Diagnosis can be made by
USG, CT as preop. Among them, CT is the radiological method with the highest
diagnostic rate. The main treatment of invagination is surgery. İn the patients
with intussusception of the small intestine, an associated primary malignancy
is uncommon. However, because of the
high likelihood of malignancy in colon intussusception, caution should be
exercised when performing resection. In this article, the patient referred to
the emergency with ileus findings and the diagnosis of intussusception was
made. Abdominal computed tomography showed small intestine intussusception. The
patient was operated. It was determined that invagination was due to adherent
mass on jejunum wall. İnitial reduction, followed by limited surgical resection
was performed. Postoperative follow-up was uneventful and the patient was
discharged. A pathological report revealed a benign polyp, no malignancy.
The level of nerve growth factor and its relationship with the content of leukocytes and mast cells in experimental interstitial cystitis/painful bladder syndrome
Authors: Sholan Rashad Farhad ogly 
Published: November 2019

Relevance. Interstitial cystitis/painful bladder syndrome (IC/PBS) is a debilitating condition of pain and discomfort in the bladder. Due to the limited number of published studies in this area, there is a need for further research.
Objective: to evaluate the level of nerve growth factor and its relationship with various types of leukocytes and mast cells of the bladder tissue in animals with experimental models of interstitial cystitis/painful bladder syndrome.
Material and methods. IC/PBS modeling was performed on 38 female rabbits. The IC/PBS modeling was created by introducing HCl into the bladder (group 1), urine into the wall of the bladder (group 2), and physiological saline (group 3). Nerve growth factor (NGF) was determined by the ELISA method, and white blood cells along with mast cells in tissues were determined by histological processing.
Results. A statistically significant high level of NGF in blood and urine was observed on the 1st day after IC/PBS initiation in groups 13 and in group 2 respectively. Two weeks after the initiation of IC/PBS in animals of group 1 a decrease in the level of FRN in the blood by 29.3% and its increase in urine by 14.3% was observed; in group 2 an increase by 65.5% (p 0.01) in blood and by 52.7% (p 0.01) in urine was observed and in group 3 a decrease by 30.8% (p 0.05) in blood and by 30.5% (p 0.05) in urine was observed. The greatest number of leukocytes was determined in the tissue of the bladder in animals of the 1st group. Mast cell infiltration was observed in groups 1 and 2. Correlation between the NGF in blood and urine and between NGF and the number of leukocytes and mast cells was revealed.
Findings. In IC/PBS, the level of NGF in the blood and urine is increased. Indicators of nerve growth factor in blood and urine are correlated with multidirectional connections. High mast cell infiltration occurs when damage to the integrity of the bladder by urinary toxicity. Nerve growth factor correlates with leukocyte and mast cell infiltration in the bladder tissue.
Conclusion. During IC/PBS, the level of NGF in the blood and urine is increased. Levels of nerve growth factor in blood and urine are correlated with multidirectional connections. High mast cell infiltration occurs as a response to the damage of the bladder wall integrity caused by urinary toxicity. The level of nerve growth factor correlates with the bladder tissue intensity of infiltration with leukocytes and mast cells.