bluuebunny/crossref_metadata_2025_split huggingface dataset:
State Preemption of Local Immigration “Sanctuary” Policies: Legal Considerations
Authors: Hall Mark A. , Mann-Jackson Lilli , Rhodes Scott D. 
Published: December 2020

States have enacted a wave of statutes over the past several years preempting local government law and policies that potentially promote public health in various ways. Among these local preemption measures are statutes in at least 9 states that outlaw municipal policies providing some form of “sanctuary” to immigrants. Such policies, and their preemption, have importance both for direct access to health services and for broader social determinants of health. This article gauges the coverage and potential impact of these state preemption laws based on key informant interviews nationally and a close legal analysis of relevant laws and policy documents. It distinguishes between preemption laws focused on law enforcement cooperation and those that also encompass a wider array of “welcoming” policies and initiatives. It also distinguishes between more passive forms of preemption that prohibit barring cooperation with federal immigration enforcement, and those statutes that more affirmatively require active measures to assist federal enforcement. Drawing these distinctions can help municipalities determine which immigrant-supportive measures are still permitted, and how best to mitigate the adverse public health effects of these preemption laws.
MAPK14-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease
Authors: Chen Jialong , Mao Kanmin , Yu Honglin , Wen Yue , She Hua , Yang Liuna , Zhang He , Li Huihui , Wu Xian , Ren Yixian , li wenjun , Zou Fei 
Published: December 2020

Abstract
Background Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc), accompanied by chronic neuroinflammation, autophagy dysfunction and SNCA(α-synuclein) accumulation in the form of Lewy bodies. Previous studies show that misfolded SNCA upregulate the inflammatory cascade through NOX activation, which elevated ROS production in microglial cell. However, it’s still not elucidated about the molecular mechanisms between autophagy deficiency and neuroinflammation induced by SNCA accumulation in microglia.Methods We overexpress mice and BV2 cells with SNCAA53T mutant as models of early-onset Parkinson's disease and identified the mechanisms that MAPK14-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease by a series of methods of molecular biology. The results of pathology and animal behavior showed that the inhibition of MAPK14 and NLRP3 had protective effect on Parkinson's disease model.Results Here, we report that MAPK14 (p38α) activates NLRP3 inflammasome via inhibiting TFEB in BV2 cells. Transcription Factor EB (TFEB) signaling negatively regulates NLRP3 inflammasome through increasing LAMP2A expression, which binds to NLRP3 and promotes its degradation via chaperone-mediated autophagy(CMA). Importantly, both MAPK14 inhibitor SB203580 and NLRP3 inhibitor MCC950 not only prevents neurodegeneration in vitro, but also alleviates movement impairment and SNCA/α-synuclein abnormal accumulation in SNCAA53T-tg mice model of Parkinson’s disease.Conclusion Our research reveals an endogenous regulatory mechanism of NLRP3 turnover and microglia-dopaminergic neuron interaction, which may be a potential therapeutic strategy for Parkinson’s disease.
Evaluation of the Acute Effects of Traditional Persian Medicine Based Hot and Cold Foods on Metabolic Responses and Arterial Stiffness in Healthy Men: Study Protocol for a Randomized Controlled Trial
Authors: Zakerian Mohsen , Roudi Fatemeh , Rezvani Reza , Motavasselian Malihe 
Published: December 2020

Abstract
Background: Traditional Persian Medicine (TPM)-based temperament is affected by some determinant factors that seems to have close similarities to resting energy expenditure (REE) and thermic effect of food (TEF) determinants. Pulse characteristics is considered as a main tool distinguishing different temperaments and vascular function and the probability of cardiovascular events are different in hot and cold-temper individuals in TPM point of view. Additionally, all foods are divided into cold/hot-temper and dry/wet-temper in this medical school and may lead to different responses in subjects regarding their temperaments.Methods: This experiment will be an acute phase study that will be performed on two groups of healthy individuals with normal body mass index (BMI) with hot and cold temperament. Each person will receive two TPM-based hot/cold isocaloric breakfast meals in 2 different days and metabolic responses and arterial stiffness indices thorough blood samples, indirect calorimetry, and pulse wave analysis and velocimetry will be assessed at fasting state, 0.5, 2, and 4 hours following meal consumption. Discussion: We will investigate the metabolic differences between individuals with TPM-based hot and cold temperaments and also to evaluate the effects of different TPM-based temperament of isocaloric meals (hot and cold) on metabolic responses and arterial stiffness indices in TPM-based hot/cold temper healthy men in this study. The results of this research project may lead to design of novel combined TPM and modern nutrition-based diet planning to improve metabolic responses and vascular reactivity. Trial registration: International Clinical Trials Registry Platform IRCT20200417047105N1, retrospectively registered at 19/04/2020. URL: https://irct.ir/trial/47267.
El archivo y la biblioteca: una provocación para otra historia de la arquitectura del siglo XIX
Authors: Barrera Rubio Hernández M. Fernanda 
Published: December 2020

<p class="p1">Este artículo busca ser una provocación de nuevos discursos a partir de los materiales de archivos arquitectónicos, entendidos más allá de los registros directos de la ideación y construcción de edificaciones, así como de planos y dibujos de personajes notables de la disciplina. En este sentido, a partir de una disertación sobre los acervos que pertenecieron a la Academia de San Carlos en la Ciudad de México, y en particular las publicaciones de su biblioteca, se cuestiona sobre su lugar en las historias de la institución y de la arquitectura mexicana del siglo XIX.<span class="Apple-converted-space"> </span></p>
2019 Health Care & Education Presidential Address: It’s All About Access!
Authors: Youssef Gretchen A. 
Published: December 2020

This article is adapted from a speech Ms. Youssef delivered as President, Health Care & Education, of the American Diabetes Association at its 79th Scientific Sessions in San Francisco, CA, on 8 June 2019.
Diabetes care management and prevention are national priorities with significant health and economic consequences at the patient, provider, and system levels. Gretchen Youssef, MS, RD, CDCES, program director of the MedStar Health Diabetes Institute, is a registered dietitian and diabetes care and education specialist who serves diabetes clinical, education, research, and quality improvement initiatives across the 10-hospital MedStar Health System in Washington, DC, and Maryland.
Ms. Youssef began her research career with the MedStar Health Research Institute and the National Institutes of Health Diabetes Prevention Program. She then joined the MedStar Health Diabetes Institute, where she continues her interests in diabetes prevention, diabetes self-care management, delivery of community-based diabetes self-management education, examination of physical activity and food choices in urban older women, and development and validation of the “KNOW Diabetes” Survival Skills Knowledge test, which can be used to identify self-care knowledge deficits in adults with type 2 diabetes. Over the past decade, she has focused on health services research addressing real-world delivery of evidence-based type 2 diabetes care management and the changing role of the diabetes care and education specialist in diabetes care. Ms. Youssef is committed to improving lives of people with diabetes, especially those who are challenged by low health literacy and socioeconomic and mental health barriers, which often prevent them from accessing and receiving optimal care. Throughout her career she has been an active member of the American Diabetes Association.
Evaluasi Kualitatif Penggunaan Antibiotik pada Pasien Infeksi Saluran Kemih dengan Metode Gyssens
Authors: Anggraini Wirda , Candra Tifany Maulida , Maimunah Siti , Sugihantoro Hajar 
Published: December 2020

Abstract—Urinary Tract Infection (UTI) was the presence of the large number of microorganisms in the urine that can cause urinary tract infections. UTIs were infection whose incidence is still high in Indonesia. The main therapy of UTIs was using antibiotics. The immense of antibiotic use can cause irrationality. This irrationality would give some negative effects such as allergic reaction, physiological changes, and antibiotic resistance. The purpose of this study was to know the quality of antibiotic use in UTI patients in Kanjuruhan Region General Hospital. The type of research was observational by the cross-sectional design. The data were taken retrospectively during September-November 2019 and used the medical records of 27 UTI inpatients. The results of this study determined 20% including category 0 (approriate use of antibiotic), 2,86% category I (antibiotic use not correct timing); 28,57% category II A (antibiotic use not correct dose); 34,29% category II B (antibiotic use not correct interval); 11,42% category III B (antibiotic use is too short) and 2,86% category IV A (there is more effective alternative). Keywords: antibiotic, gyssens, urinary tract
Abstrak—Infeksi Saluran Kemih (ISK) merupakan suatu keadaan dimana terdapat mikroorganisme dalam urin yang jumlahnya sangat banyak dan mampu mengakibatkan infeksi pada saluran kemih. ISK tergolong penyakit infeksi yang angka kejadiannya masih tinggi di Indonesia. Terapi utama ISK adalah terapi dengan menggunakan antibiotik. Meluasnya penggunaan antibiotik dapat menyebabkan tidak rasionalnya penggunaan antibiotik. Penatalaksanaan terapi antibiotik yang tidak rasional dapat menimbulkan risiko antara lain adalah reaksi alergi, toksisitas, perubahan fisiologi, dan resistensi antibiotik. Tujuan penelitian ini adalah untuk mengetahui kualitas penggunaan antibiotik pada pasien ISK di RSUD Kanjuruhan Kabupaten Malang. Jenis penelitian adalah observasional dengan menggunakan desain penelitian cross-sectional. Pengambilan data dilakukan secara retrospektif selama bulan September-November 2019 dan menggunakan 27 data rekam medik pasien ISK Rawat Inap. Hasil evaluasi kualitatif menunjukkan, sebesar 20% termasuk kategori 0 (penggunaan antibiotik tepat/bijak); 2,86% kategori I (penggunaan antibiotik tidak tepat waktu); 28,57% kategori II A (penggunaan antibiotik tidak tepat dosis); 34,29% kategori II B (penggunaan antibiotik tidak tepat interval pemberian); 11,42% kategori III B (penggunaan antibiotik terlalu singkat); dan 2,86% kategori IV A (ada antibiotik lain yang lebih efektif). Kata kunci : antibiotik, gyssens, infeksi saluran kemih
The Combination of Arbuscular Mycorrhizal Fungi with Rock Powder and Poultry Litter: An Appropriate Natural Fertiliser for Improving the Productivity of Soybean (Glycine max (L.) Merr)
Authors: Fabrice Kamdem Kaigom , Lucien Tchuenteu Tatchum , Abba Maimouna , Clautilde Megueni 
Published: December 2020

Abstract
The present study aimed to evaluate the effect of the combination of various natural fertilisers on growth and seed yield of the soybean plants. Field experimentations were carried out during two cropping seasons (2018 and 2019). A randomized complete block experimental design with 11 treatments (F1: 30 g of poultry litter, F2: 60 g of poultry litter, MP: 10 g of mycorrhizae + 10 g of vivianite powder, MF1: 10 g of mycorrhizae + 30 g of poultry litter, MF2: 10 g of mycorrhizae + 60 g of poultry litter, PF1: 10 g of vivianite powder + 30 g of poultry litter, PF2: 10 g of vivianite powder + 60 g of poultry litter, MPF1: 10 g of mycorhizae + 10 g of vivianite powder + 30 g of poultry litter, MPF2: 10 g of mycorrhizae + 10 g of vivianite powder + 60 g of poultry litter, T+: chemical fertiliser, T–: unfertilised plants) and three replications were used. The growth parameters and seed yield were evaluated. The results showed that the growth and seed yield of soybean varied depending on the fertiliser and the cropping season. Plants that have received the MPF2 treatment exhibited significantly (p ˂ 0.05) the highest values of the studied parameters (plants height, foliar production, plants dry biomass, seed yield). The MPF2 treatment increased the seed yield of soybean by 20.08% and 184.76% compared to T+ and T– treatments, respectively. The supply of the following combination, 10 g of mycorrhizae + 10 g of vivianite powder + 60 g of poultry litter was found to be very promising in improving the soybean plant growth and therefore, can be used as an alternative to replacing the mineral fertilisers usually employed for the cultivation of this crop.
Genetic variation of the major histocompatibilty complex-B haplotypes in Nigerian local chicken populations
Authors: Olufowobi Olanrewaju Teslim , Ilori Babatunde Moses , Olowofeso Olajide , Sogunle Olajide Mark , Omotoso Adewunmi Omolade 
Published: December 2020

Abstract
To understand the genetic basis and mechanism underlying the differences in the level of immunity among and within chicken populations in Nigeria, it is important to start from the Major Histocompability Complex (MHC) region particularly as it serves as a reservoir for genes of the immune system. The B-complex of chicken major histocompatibility complex, located on microchromosome 16, consists of gene classes responsible for immunity through antigen presentation to T cells. A highly polymorphic tandem repeat marker (LEI0258) located within the B-complex has been a marker of choice for genotyping to identify major histocompatibility complex-B haplotypes and to study the genetic diversity of chicken populations. This study was carried out to determine the genetic variations, at the LEI0258 locus, in three Nigerian local chicken populations; Normal feather, Frizzle feather and Naked neck. The allelic and genotypic profiles of each representative from each population were determined through polymerase chain reaction amplification of the repeat region. The genetic diversity parameters, analysis of molecular variance and evolutionary relationship were determined using GenAlex, FSTAT, Arlequin and POPTREEW, respectively. 76 % of the entire population was heterozygous at the LEI0258 locus. Analysis of molecular variance revealed that large proportion of the total variations across populations was due to variation between individuals (79 %), whereas variations among the populations and among individuals within populations only accounted for less than 1 % and 21 %, respectively. Using Anak Titan as an exotic outgroup, the evolutionary relationship among the Nigerian local chicken populations was studied and a Nei-based dendrogram showed two major clades separating the exotic population from the Nigerian local chicken populations. The identified diversity at the locus could be exploited for usage in further breeding programmes especially for disease resistance and fitness in locally adapted chicken populations in Nigerian.
An investigation of the effects of organisational communication on work outcomes within agriculture research institutes in Nigeria
Authors: Oso Oluwatoyin Aduke , Lawal-Adebowale Okanlade Adesokan , Aduradola Remi Rebecca , Adigun James Kehinde 
Published: December 2020

Abstract
The study investigated the effects of organisational communication on work outcomes (job satisfaction, affective commitment and quit-intentions) of agriculture research personnel from six research institutes in Nigeria. Further, the mediational role of job satisfaction was determined among the constructs. Simple random sampling technique was used to elicit information from 209 researchers of the selected research institutes. Data were collected through a well-structured questionnaire and analysed using hierarchical regression and Sobel tests. Results obtained from hierarchical regression analyses indicated that organisational communication was related to job satisfaction (b = 0.18, P < 0.01), affective commitment (b1 = 0.20, P < 0.01) and quit-intentions (b1 = – 0.18, P < 0.01). Sobel test indicated that job satisfaction partially mediated the organisational communication-affective commitment relationship (Z = 5.42, P < 0.05). Similarly, job satisfaction was a partial mediator of the organisational communication – quit-intention relationship (Z = 4.13, P < 0.05). This is an indication that increased organisational communication fosters personnel’s satisfaction with job, improves affective commitment and reduces intents of quitting the organisation. Evidence of partial mediation revealed that job satisfaction may not be the only mediator of the predictor-criterions linkages.
Investigation of Electronic and Optical Properties of Novel Oxychalcogenides by Density Functional Theory
Authors: Moufok S. , Amrani B. 
Published: December 2020

AbstractThe search for a new material with unparalleled properties has attracted the interest of the scientific community due to rapid development of technology and it can be very inspiring to the future experiments. In this paper, electronic structure and optical properties of the new rare earth coinage-metal chalconegides YCuChO (Ch=S, Se, Te) are investigated in detail using state-of-the art density functional theory (DFT). Both the GGA-PBEsol and TB-mBJ functionals were used to describe the exchange-correlation interactions. These compounds are novel and have not been synthesized before. The optimized structural parameters, viz., lattice parameters and atomic position coordinates, are predicted. The analyses of the electronic properties indicate that the studied compounds are wide direct bandgap semiconductors. The calculated bandgaps varying from 1.69 eV (for the Te compound) to 2.5 eV (for the S compound) with the mBJ approach. Moreover, the optical properties of these compounds were comprehensively studied and discussed in terms of the dielectric function and loss function. The results provide theoretical support for the exploration of YCuChO (Ch=S, Se, Te) materials in potential optoelectronic applications.
Data Mining Applications in SMEs: An Italian Perspective
Authors: Topalović Amir , Azzini Antonia 
Published: December 2020

Abstract

Background
From the last decade, data mining techniques, employed in particular in customer relationship management, have assumed a key role in the profitability and operations of companies. To support small and medium companies (SMEs), several innovative and continuously improving tools have been developed that allow SMEs to utilize the internal and external data sources to increase their competitiveness.

Objectives
In this paper, an analysis of the impact of digitalization, and in particular data mining techniques, in the context of SMEs development is presented.

Methods/Approach
A review of various sources has been conducted, with the focus on open source tools, since in the context of the Italian economy they are used by SMEs the most.

Results
First, the analysis presents a brief review of the data mining techniques available and shows how they are practically employed in small companies. Second, an economical review of investments in data mining projects in Italy is presented.

Conclusions
The review indicates that data mining techniques can boost a company in the market. However, the awareness of data mining as a company asset is still not strong in Italian SMEs and most investments in Italy are still carried out by large companies.
Euthanasia as an issue in ethics of social consequences?
Authors: Kalajtzidis Ján 
Published: December 2020

Abstract
The main aim of the presented paper is to look for an answer as to whether and how euthanasia reflected is in ethics of social consequences. Ethics of social consequences is a contemporary Slovak ethical theory with an original approach to delimitating moral agency. The paper puts this definition to the test while considering the main focus of the paper – responding to the question of whether euthanasia and end of life can be understood as a moral uncertainty. The intention is to find out whether the definition is clear and adequate to withstand the basic arguments against euthanasia. Since ethics of social consequences is a consequentialist ethical theory, another partial goal is to analyse the fitness of such a position to be used in bioethical inquires.
Forest site conditions and the threat for insect outbreaks in the Scots pine stands of Polissya
Authors: Andreieva Olena , Goychuk Anatoliy 
Published: December 2020

Abstract
Scots pine (Pinus sylvestris L.) is the most spread forest tree species in Polissya and the most damaged by foliage browsing and stem insects. The aim of this study was to reveal the changes in the distribution of different forest site conditions for 2010–2019 in Scots pine forests of the selected forestry enterprises of Polissya and possible consequences for the spread of foliage browsing insects. Database of Production Association ‘Ukrderzhlisproekt’ (by 2010 and 2019) was analysed for five State Forest Enterprises (FE) that are located in the Central (Zhytomyr Region) and Western (Rivne and Volyn Regions) Polissya, where the large scale outbreaks of stem pests were registered last decade.
The types of forest site conditions were designated in accordance with the Ukrainian typology. Distribution of the forest area by trophotops and hygrotops was evaluated for the forest-covered area, for Scots pine stands, and for pure Scots pine stands in 2010 and in 2019.
For 2010–2019, the area of all Scots pine forests and its proportion in the forest-covered area has significantly decreased in the most of analysed forest enterprises. The change for 2010–2019 in the distribution both by the tropho-tops and by hygrotops of the entire forest-covered area, the area of all Scots pine forests and pure pine forests is not statistically significant. However, in assessment year 2019, the proportion of stands in the moist types of forest site conditions slightly increased. It may be the result of the stands’ mortality in the driest sites after an outbreak of bark beetles. A greater decrease in the proportion of Scots pine forest area in the dry poor, fresh poor, and dry relatively poor forest site conditions was found in the western direction. Therefore, the noted decrease in the foci areas of foliage browsing insects in Polissya in 2010–2012 compared to the 2000–2002 could be associated with a decrease in the most preferred stands, namely the poorest and driest types of forest site conditions.