bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mental Health Service Utilization and Perceived Barriers to Receiving Care in Deployed Soldiers
Authors: Nugent Katie L , Riviere Lyndon A , Sipos Maurice L , Wilk Joshua E 
Published: March 2020

Abstract

Introduction
Scant research has examined mental health treatment utilization and barriers to care in deployed U.S. soldiers. This study aims to assess mental health treatment utilization in deployed soldiers, including providers used and barriers to care.

Materials and Methods
U.S. Army soldiers (n = 2,412) in a combat environment were surveyed on psychiatric symptoms, mental health help received, sources of care, and perceived barriers to care by Mental Health Advisory teams from 2009 to 2013.

Results
Of the 25% of soldiers at mental health risk, 37% received mental health help, with 18% receiving help from a provider. Nonprovider sources of care were utilized significantly more frequently than providers. Soldiers at mental health risk reported significantly greater anticipated career-related stigma, organizational barriers to care, self-reliance views, and negative attitudes toward care, yet these constructs did not differ between who did or did not receive help. Soldiers who received help from providers exclusively reported significantly more anticipated career-related stigma and fewer organizational barriers to care than those that received no help. Soldiers who spent no time living outside the forward operating base and soldiers with six or more types of combat exposures were more likely to receive help.

Conclusions
Prevalence of common psychopathology and receipt of care in a combat environment was similar to previous reports from postdeployment settings. Nonprovider sources of care were more frequently utilized as compared to an in-Garrison report. Findings suggest important differences exist in sources of help and barriers to care in deployed vs. postdeployment environments. The hypothesized barriers to care did not preclude receiving any help, however, less than one-half of soldiers at mental health risk received help. Thus, future research should identify factors that have the greatest influence on help seeking behavior in both deployed and Garrison settings.
Searching for dark matter signals from local dwarf spheroidal galaxies at low radio frequencies in the GLEAM survey
Authors: Cook R H W , Seymour N , Spekkens K , Hurley-Walker N , Hancock P J , Bell M E , Callingham J R , For B-Q , Franzen T M O , Gaensler B M , Hindson L , Johnston-Hollitt M , Kapińska A D , Morgan J , Offringa A R , Procopio P , Staveley-Smith L , Wayth R B , Wu C , Zheng Q 
Published: March 2020

ABSTRACT
The search for emission from weakly interacting massive particle (WIMP) dark matter annihilation and decay has become a multipronged area of research not only targeting a diverse selection of astrophysical objects, but also taking advantage of the entire electromagnetic spectrum. The decay of WIMP particles into standard model particles has been suggested as a possible channel for synchrotron emission to be detected at low radio frequencies. Here, we present the stacking analysis of a sample of 33 dwarf spheroidal (dSph) galaxies with low-frequency (72–231 MHz) radio images from the GaLactic and Extragalactic All-sky Murchison Widefield Array (GLEAM) survey. We produce radial surface brightness profiles of images centred upon each dSph galaxy with background radio sources masked. We remove 10 fields from the stacking due to contamination from either poorly subtracted, bright radio sources or strong background gradients across the field. The remaining 23 dSph galaxies are stacked in an attempt to obtain a statistical detection of any WIMP-induced synchrotron emission in these systems. We find that the stacked radial brightness profile does not exhibit a statistically significant detection above the 95 per cent confidence level of ∼1.5 mJy beam−1. This novel technique shows the potential of using low-frequency radio images to constrain fundamental properties of particle dark matter.
Abundance analyses of Li-enriched and normal giants in the GALAH survey
Authors: Deepak  , Lambert David L , Reddy Bacham E 
Published: March 2020

Abstract
Compositions of lithium-enriched and normal giants among the GALAH survey are compared. Except for Li, the only detectable abundance difference between lithium-enriched and normal giants among the investigated elements from carbon to europium occurs for carbon. Among Li-rich giants with A(Li) = 1.8 to 3.1, the C deficiency is very similar to that reported for the normal giants (with A(Li) &lt; 1.8) where the slight C deficiency arises from the first dredge-up. Carbon is slightly under abundant relative to normal giants among the super Li-rich giants where the Li abundance exceeds A(Li) = 3.2. The C abundance as well as the 12C/13C ratios from the literature suggest that addition of Li to create a Li-rich giant may occur independently of the abundance changes wrought by the first dredge-up. Creation of a super Li-rich giant, however, appears to occur with additional CN-cycle conversion of C to N. The probability of becoming a Li-rich giant is approximately independent of a star’s mass, although the majority of the Li-rich giants are found to be low mass (M ≤ 2 M⊙). The frequency of occurrence of Li-enriched giants among normal giants is about one percent and slightly dependent on metallicity ([Fe/H]). Li-enriched and normal giants are found to have similar projected rotational velocity which suggest that Li-enrichment in giants is not linked to scenarios such as mergers and tidal interaction between binary stars.
Hard X-ray selected giant radio galaxies – II. Morphological evidence of restarted radio activity
Authors: Bruni G , Panessa F , Bassani L , Dallacasa D , Venturi T , Saripalli L , Brienza M , Hernández-García L , Chiaraluce E , Ursini F , Bazzano A , Malizia A , Ubertini P 
Published: March 2020

ABSTRACT
About 6 per cent of radio galaxies (RGs) can reach linear sizes larger than 0.7 Mpc, and are then classified as giant radio galaxies (GRGs). The conditions that make possible the formation of such big structures are still not clear – either core accretion properties or environmental factors. Recent studies have shown that GRGs can be up to four times more abundant in hard X-ray selected (i.e. from INTEGRAL/IBIS and Swift/BAT at &gt;20 keV) RG samples. Moreover, a high fraction of young radio sources found in their cores suggest a recently restarted activity, as suggested from the discrepancy between the measured jet and lobes power, with respect to the one expected from core X-ray luminosity. Here, we present a radio morphological study of a sample of 15 hard X-ray selected GRGs, discussing low-frequency images from our GMRT campaign complemented with others from the literature: among them, 7/15 show evidence of restarted radio activity either in the form of double–double/X-shaped morphology, or as a cocoon emission embedding more recent jets. This, together with the objects from this sample already found hosting a young radio source in their core, suggests that at least 13 over 15 of these hard X-ray selected GRGs show features that are consistent with the possibility of restarted radio activity.
Confirmed short periodic variability of subparsec supermassive binary black hole candidate Mrk 231
Authors: Kovačević Andjelka B , Yi Tignfeng , Dai Xinyu , Yang Xing , Čvorović-Hajdinjak Iva , Popović Luka Č 
Published: March 2020

ABSTRACT
Here we confirm the short periodic variability of a subparsec supermassive binary black hole (SMBBH) candidate Mrk 231 in the extended optical photometric data set collected by the Catalina Real-Time Transient Survey (CRTS) and All-Sky Automated Survey for Supernovae (ASAS-SN). Using the Lomb–Scargle periodogram and 2DHybrid method, we detected the significant periodicity of ∼1.1 yr beyond a damped random walk model in the CRTS+ASAS-SN optical data set. Mrk 231 has been previously proposed as an SMBBH candidate with a highly unequal mass ratio (q ∼ 0.03), very tight mutual separation of ∼590 au, and an orbital period of ∼1.2 yr. Hence, our result further supports, even though not prove, the intriguing hypothesis that SMBBHs with low mass ratios may be more common than close-equal mass SMBBHs. This result, however, was obtained from the contribution of the CRTS data with limited sampling cadence and photometric accuracy, and further monitoring of Mrk 231 is crucial to confirm the periodicity.
Safety and Outcomes of Linezolid Use for Nocardiosis
Authors: Davidson Natalie , Grigg Matthew J , Mcguinness Sarah L , Baird Robert J , Anstey Nicholas M 
Published: March 2020

AbstractBackgroundTropical Australia has a high incidence of nocardiosis, with high rates of intrinsic antimicrobial resistance. Linezolid, the only antimicrobial to which all local Nocardia species are susceptible, has been recommended in empirical combination treatment regimens for moderate–severe Nocardia infections at Royal Darwin Hospital (RDH) since 2014. We report the safety and efficacy of linezolid use for nocardiosis in this setting.MethodsWe identified cases through a retrospective review of all RDH Nocardia isolates from December 2014 to August 2018 and included 5 linezolid-treated cases from a previous cohort. Laboratory, demographic, and clinical data were included in the primary analysis of safety and treatment outcomes.ResultsBetween 2014 and 2018, Nocardia was isolated from 35 individuals; 28 (80%) had clinically significant infection and 23 (82%) received treatment. All isolates were linezolid-susceptible. Safety and efficacy were assessed for 20 patients receiving linezolid-containing regimens and 8 receiving nonlinezolid regimens. Median linezolid induction therapy duration was 28 days. Common adverse effects in those receiving linezolid were thrombocytopenia (45%) and anemia (40%). Adverse events prompted discontinuation of trimethoprim-sulfamethoxazole more often than linezolid (40% vs 20%). Linezolid therapeutic drug monitoring was used in 1 patient, with successful dose reduction and outcome. There was no difference in 30-day survival between those treated with linezolid (90%) vs no linezolid (87%). One Nocardia-attributed death occurred during linezolid therapy.ConclusionsLinezolid is safe and efficacious in empirical treatment for moderate to severe nocardiosis in a monitored hospital setting, with 100% drug susceptibility and no difference in adverse events or outcomes compared with nonlinezolid regimens.
Per-Contact Infectivity of Hepatitis C Virus Acquisition in Association With Receptive Needle Sharing Exposures in a Prospective Cohort of Young Adult People who Inject Drugs in San Francisco, California
Authors: Leyva Yuridia , Page Kimberly , Shiboski Stephen , Hahn Judith A , Evans Jennifer , Erhardt Erik 
Published: March 2020

Abstract

Background
Sharing needles and ancillary injecting equipment is a primary risk exposure for hepatitis C virus (HCV) infection among people who inject drugs (PWID); however, infectivity of these exposures is not well quantified. We aimed to estimate per-event HCV infectivity associated with receptive needle sharing (RNS) among susceptible PWID.

Methods
Participants in a prospective cohort study of young adult PWID who were anti-HCV and HCV RNA negative at baseline and attended at least 2 follow-up study visits between 2003 and 2014 were eligible. Data were selected from the first HCV-negative through the first HCV-positive visit (or last HCV-negative among those uninfected). Anti-HCV and HCV-RNA tests were used to determine infection status. A probabilistic exposure model linking observed HCV infection outcomes to self-reported exposure events was applied to estimate infectivity.

Results
Among 344 participants, a maximum likelihood estimate considering RNS yielded a pooled population per RNS event HCV probability of 0.25% (95% confidence interval [CI], 0.10%–0.43%), and 1.12% (95% CI, 0.48%–2.35%) among those who acquired any HCV infection (primary or reinfection).

Conclusions
HCV is highly infectious in association with RNS, a primary injection-related risk exposure. Our infectivity estimate among participants who acquired any HCV infection is 1.7 times higher than that estimated for HIV infection in PWID and 2.24 times higher than that estimated among health care workers exposed through needle sticks. The strengths of this study include the assessment of receptive needle sharing events, the prospective design, and relatively short recall and testing periods. These results can inform transmission models and research to prevent HCV infection.
Microbiology and Risk Factors for Hospital-Associated Bloodstream Infections Among Pediatric Hematopoietic Stem Cell Transplant Recipients
Authors: Akinboyo Ibukunoluwa C , Young Rebecca R , Spees Lisa P , Heston Sarah M , Smith Michael J , Chang Yeh-Chung , McGill Lauren E , Martin Paul L , Jenkins Kirsten , Lugo Debra J , Hazen Kevin C , Seed Patrick C , Kelly Matthew S 
Published: March 2020

Abstract

Background
Children undergoing hematopoietic stem cell transplantation (HSCT) are at high risk for hospital-associated bloodstream infections (HA-BSIs). This study aimed to describe the incidence, microbiology, and risk factors for HA-BSI in pediatric HSCT recipients.

Methods
We performed a single-center retrospective cohort study of children and adolescents (&lt;18 years of age) who underwent HSCT over a 20-year period (1997–2016). We determined the incidence and case fatality rate of HA-BSI by causative organism. We used multivariable Poisson regression to identify risk factors for HA-BSI.

Results
Of 1294 patients, the majority (86%) received an allogeneic HSCT, most commonly with umbilical cord blood (63%). During the initial HSCT hospitalization, 334 HA-BSIs occurred among 261 (20%) patients. These were classified as gram-positive bacterial (46%), gram-negative bacterial (24%), fungal (12%), mycobacterial (&lt;1%), or polymicrobial (19%). During the study period, there was a decline in the cumulative incidence of HA-BSI (P = .021) and, specifically, fungal HA-BSIs (P = .002). In multivariable analyses, older age (incidence rate ratio [IRR], 1.03; 95% confidence interval [CI], 1.01–1.06), umbilical cord blood donor source (vs bone marrow; IRR, 1.69; 95% CI, 1.19–2.40), and nonmyeloablative conditioning (vs myeloablative; IRR, 1.85; 95% CI, 1.21–2.82) were associated with a higher risk of HA-BSIs. The case fatality rate was higher for fungal HA-BSI than other HA-BSI categories (21% vs 6%; P = .002).

Conclusions
Over the past 2 decades, the incidence of HA-BSIs has declined among pediatric HSCT recipients at our institution. Older age, umbilical cord blood donor source, and nonmyeloablative conditioning regimens are independent risk factors for HA-BSI among children undergoing HSCT.
Low Sensitivity of Procalcitonin for Bacteremia at an Academic Medical Center: A Cautionary Tale for Antimicrobial Stewardship
Authors: Goodlet Kellie J , Cameron Emily A , Nailor Michael D 
Published: March 2020

Abstract

Background
Procalcitonin testing has been adopted by antimicrobial stewardship programs as a means of reducing inappropriate antibiotic use, including within intensive care units (ICUs). However, concerns regarding procalcitonin’s sensitivity exist. The purpose of this study is to calculate the sensitivity of procalcitonin for bacteremia among hospitalized patients.

Methods
This was a retrospective cohort study of adult patients admitted to an academic medical center between July 1, 2018, and June 30, 2019, with ≥1 positive blood culture within 24 hours of admission and procalcitonin testing within 48 hours. Low procalcitonin was defined as &lt;0.5 µg/L.

Results
A total of 332 patients were included. The sensitivity of procalcitonin for bacteremia was 62% at the sepsis threshold of 0.5 µg/L, 76% at a threshold of 0.25 µg/L, and 92% at a threshold of 0.1 µg/L. Of the 125 patients with low procalcitonin, 14% were initially admitted to the ICU and 9% required the use of vasopressors. In that same group, the top 3 organisms isolated were Staphylococcus aureus (39%), Escherichia coli (17%), and Klebsiella spp. (7%). Compared with those patients with elevated procalcitonin, patients with low procalcitonin were significantly more likely to have &gt;24-hour delayed receipt of antibiotic therapy (3% vs 8%; P = .04), including among patients admitted to the ICU (1% vs 18%; P = .02).

Conclusions
The sensitivity of procalcitonin for bacteremia is unacceptably low for a rule-out test. Antimicrobial stewardship programs should use caution before promoting the withholding of antibiotic therapy for patients with low initial procalcitonin values.
Oxytocin and the stress buffering effect of social company: a genetic study in daily life
Authors: Sicorello Maurizio , Dieckmann Linda , Moser Dirk , Lux Vanessa , Luhmann Maike , Schlotz Wolff , Kumsta Robert 
Published: March 2020

Abstract
Social relationships are a crucial determinant of both mental and physical health. This effect is partly due to social buffering of stress. Animal studies suggest that social buffering is mediated via the oxytocin system, while studies in humans are sparse and limited by the low ecological validity of laboratory settings. In the present study, participants (N = 326) completed smartphone questionnaires four times a day over 4 to 5 days, measuring stressors, negative affect, and social context to assess social buffering. We found that under stress, participants reported a higher need for social company. Further, the impact of prior stressful events on momentary negative affect was attenuated by the perceived pleasantness of current social company. This social buffering effect was moderated by haplotypes of the oxytocin receptor gene, based on two well-described single nucleotide polymorphisms (rs2268498, rs53576). Effects were robust when controlling for gender and age, applying different data quality criteria, and even apparent in genotype-based analyses. Our findings demonstrate that social buffering and its modulation by oxytocin system characteristics have implications for life as lived outside the laboratory.
Evaluating the Performance of Probabilistic Algorithms for Phylogenetic Analysis of Big Morphological Datasets: A Simulation Study
Authors: Vernygora Oksana V , Simões Tiago R , Campbell Erin O 
Published: March 2020

AbstractReconstructing the tree of life is an essential task in evolutionary biology. It demands accurate phylogenetic inference for both extant and extinct organisms, the latter being almost entirely dependent on morphological data. While parsimony methods have traditionally dominated the field of morphological phylogenetics, a rapidly growing number of studies are now employing probabilistic methods (maximum likelihood and Bayesian inference). The present-day toolkit of probabilistic methods offers varied software with distinct algorithms and assumptions for reaching global optimality. However, benchmark performance assessments of different software packages for the analyses of morphological data, particularly in the era of big data, are still lacking. Here, we test the performance of four major probabilistic software under variable taxonomic sampling and missing data conditions: the Bayesian inference-based programs MrBayes and RevBayes, and the maximum likelihood-based IQ-TREE and RAxML. We evaluated software performance by calculating the distance between inferred and true trees using a variety of metrics, including Robinson-Foulds (RF), Matching Splits (MS), and Kuhner-Felsenstein (KF) distances. Our results show that increased taxonomic sampling improves accuracy, precision, and resolution of reconstructed topologies across all tested probabilistic software applications and all levels of missing data. Under the RF metric, Bayesian inference applications were the most consistent, accurate, and robust to variation in taxonomic sampling in all tested conditions, especially at high levels of missing data, with little difference in performance between the two tested programs. The MS metric favored more resolved topologies that were generally produced by IQ-TREE. Adding more taxa dramatically reduced performance disparities between programs. Importantly, our results suggest that the RF metric penalizes incorrectly resolved nodes (false positives) more severely than the MS metric, which instead tends to penalize polytomies. If false positives are to be avoided in systematics, Bayesian inference should be preferred over maximum likelihood for the analysis of morphological data.
Here comes the flood! Stress effects of continuous and interval waterlogging periods during the growing season on Scots pine saplings
Authors: Domisch Timo , Qian Ji , Sondej Izabela , Martz Françoise , Lehto Tarja , Piirainen Sirpa , Finér Leena , Silvennoinen Raimo , Repo Tapani 
Published: March 2020

Abstract
Future climate scenarios for the boreal zone project increasing temperatures and precipitation, as well as extreme weather events such as heavy rain during the growing season. This can result in more frequent short-term waterlogging (WL) leading to unfavorable conditions for tree roots. In addition, it is decisive whether short-term WL periods during the growing season occur continuously or periodically. We assessed the effects of short-termed WL on 4-year-old Scots pine (Pinus sylvestris L.) saplings after shoot elongation started. Waterlogging (WL) lasted either continuously for 2.5 weeks (ContWL) or noncontinuously for 5 weeks, consisting of three repeated 1-week-interval WL periods (IntWL). Both treatments resulted in the same duration of soil anoxia. We studied soil gases, root and shoot growth and physiology, and root survival probability and longevity during the experiment. In the final harvest, we determined shoot and root biomass and hydraulic conductance and electrical impedance spectra of the root systems. Soil CO2 and CH4 concentrations increased immediately after WL onset and O2 decreased until anoxia. Waterlogging decreased fine root survival probability, but there was no difference between WL treatments. Shoot growth suffered more from ContWL and root growth more from IntWL. Needle concentrations of pinitol increased in the WL saplings, indicating stress. No WL effects were observed in photosynthesis and chlorophyll fluorescence. Increased starch concentration in needles by WL may be due to damaged roots and thus a missing belowground sink. Electrical impedance indicated suffering of WL saplings, although root hydraulic conductance did not differ between the treatments. Oxidative stress of short-term and interval WL can have long-lasting effects on shoot and root growth and the physiology of Scots pine. We conclude that even short-term WL during the growing season is a stress factor, which will probably increase in the future and can affect carbon allocation and dynamics in boreal forests.