bluuebunny/crossref_metadata_2025_split huggingface dataset:
“What is done and what is left to be done?” An investigation of YouTube as knowledge resource for Islamic endowment funds (cash waqf) in Indonesia
Authors: Pusparini Martini Dwi , Sukmana Raditya , Napitupulu Rodame Monitorir 
Published: December 2024

Purpose
This study aimed at exploring to what extent social media has educated and shaped public opinion regarding cash waqf. This research comprehensively analyzed the social media content to find the most discussed topic and highlighted the trends in cash waqf literacy.

Design/methodology/approach
Twenty-nine videos discussing cash waqf in Indonesia from the YouTube platform were analyzed using NVivo R1 with a content analysis approach.

Findings
The research findings revealed that YouTube videos addressing cash waqf were categorized into four distinct clusters: government, ulama/influencers/professionals, nadzir (waqf manager) and TV stations, with the government cluster producing a higher number of videos (n = 11) than the other clusters. The findings also highlighted the limited involvement of nadzir in educating the public about cash waqf, as evidenced by a smaller number of videos (n = 5). Among these videos, the most frequently discussed topics included the utilization of cash waqf (n = 20), promotion of cash waqf (n = 14) and risk management (n = 13). Negative sentiment (n = 262) was observed to exceed positive sentiment (n = 107).

Practical implications
The findings of this study contribute to the fundraising aspect of cash waqf because the inclusivity of digital content in cash waqf campaigns is crucial to raise awareness of the public. In addition, these findings may help waqf managers (nadzir) assess the extent of educational content about cash waqf on YouTube and the public’s response to this content.

Originality/value
To the best of the authors’ knowledge, this study is the first to analyze the social media content, particularly from YouTube platforms, and public sentiment against cash waqf.
Social Capital and Cultural Health Capital in Primary Care: The Case of Group Medical Visits
Authors: Thompson‐Lastad Ariana , Harrison Jessica M. , Shim Janet K. 
Published: December 2024

ABSTRACTThis article focuses on an empirical setting that upends the clinician–patient dyadic norm: group medical visits (GMVs), in which multiple patients gather in the same space for medical care, health education and peer support. Our grounded theory analysis draws on participant observation and interviews (N = 53) with patients and staff of GMVs at four safety‐net healthcare organisations in the United States. We delineate (1) how group medical visits provide health‐focused social networks that facilitate the mobilisation of social capital, (2) how the organisationally embedded relationships that comprise group visits are made possible through extended time that is part of the GMV field and (3) how clinicians have opportunities rarely found in other settings to learn from patients, using knowledge accrued from GMV networks to advance their own skills, thereby converting social capital into provider cultural health capital. GMVs provide a rich empirical site for understanding the ways in which organisational arrangements can shape opportunities for patients and clinicians to cultivate and mobilise social capital and cultural health capital, and in doing so, materially shift experiences of receiving and providing healthcare.
The Value of Centre for Employee Relations and Communication (CERC) for Research and Professional Advancement: Insights From the Pandemic Crisis and Beyond
Authors: Mazzei Alessandra , Butera Alfonsa 
Published: December 2024

ABSTRACTThe Centre for Employee Relations and Communication (CERC) operating at Università IULM in Italy represents an experience of academia‐industry collaboration through a multi‐company research group: the Working Group Employee Communication (WG_EC). The article depicts the efforts that the WG_EC has been putting into the specific research area of internal crisis communication over its 15 years of activity. Through a qualitative study involving 13 professionals that were partners of the WG_EC, it also sheds light on the value generated for company partners from the collaboration with the academic experts of CERC during the COVID‐19 pandemic. The study also reflects upon the professional and research advancement boosted by the CERC and its WG_EC beyond that specific critical event, and to focus on issues that WG_EC professionals consider particularly relevant for the future.
Food packaging solutions in the post‐per‐ and polyfluoroalkyl substances (PFAS) and microplastics era: A review of functions, materials, and bio‐based alternatives
Authors: Yashwanth Arcot , Huang Rundong , Iepure Monica , Mu Minchen , Zhou Wentao , Kunadu Angela , Carignan Courtney , Yegin Yagmur , Cho Dongik , Oh Jun Kyun , Taylor Matthew T. , Akbulut Mustafa E. S. , Min Younjin 
Published: December 2024

AbstractFood packaging (FP) is essential for preserving food quality, safety, and extending shelf‐life. However, growing concerns about the environmental and health impacts of conventional packaging materials, particularly per‐ and polyfluoroalkyl substances (PFAS) and microplastics, are driving a major transformation in FP design. PFAS, synthetic compounds with dual hydro‐ and lipophobicity, have been widely employed in food packaging materials (FPMs) to impart desirable water and grease repellency. However, PFAS bioaccumulate in the human body and have been linked to multiple health effects, including immune system dysfunction, cancer, and developmental problems. The detection of microplastics in various FPMs has raised significant concerns regarding their potential migration into food and subsequent ingestion. This comprehensive review examines the current landscape of FPMs, their functions, and physicochemical properties to put into perspective why there is widespread use of PFAS and microplastics in FPMs. The review then addresses the challenges posed by PFAS and microplastics, emphasizing the urgent need for sustainable and bio‐based alternatives. We highlight promising advancements in sustainable and renewable materials, including plant‐derived polysaccharides, proteins, and waxes, as well as recycled and upcycled materials. The integration of these sustainable materials into active packaging systems is also examined, indicating innovations in oxygen scavengers, moisture absorbers, and antimicrobial packaging. The review concludes by identifying key research gaps and future directions, including the need for comprehensive life cycle assessments and strategies to improve scalability and cost‐effectiveness. As the FP industry evolves, a holistic approach considering environmental impact, functionality, and consumer acceptance will be crucial in developing truly sustainable packaging solutions.
Fermented soy products: A review of bioactives for health from fermentation to functionality
Authors: Harahap Iskandar Azmy , Suliburska Joanna , Karaca Asli Can , Capanoglu Esra , Esatbeyoglu Tuba 
Published: December 2024

AbstractThe increasing prevalence of metabolic diseases and the global drive toward achieving Sustainable Development Goals (SDGs) underscore the need for sustainable, nutrient‐dense foods. Soybeans (Glycine max), a critical global crop, offer promising solutions; however, their predominant use as animal feed raises concerns regarding food security and environmental sustainability. Fermented soy products—including tempeh, natto, and miso—are rich in bioactive compounds such as peptides and isoflavones, which offer potential therapeutic effects and hold cultural and nutritional significance. These fermented products provide bioactive profiles with unique health‐promoting properties. This review critically examines the bioactive compounds generated through fermentation, focusing on their bioconversion pathways in the gastrointestinal tract and their metabolic implications for human health. Recent consumer demand for novel food ingredients with additional biological benefits has fueled research into advanced extraction techniques, enhancing the functional applications of bioactive compounds from these soy‐based products. This review further explores innovations in extraction methods that improve bioactive yield and sustainability, reinforcing the applicability of these compounds in health‐promoting food interventions. The originality of this review lies in its in‐depth exploration of the gastrointestinal bioconversion of fermented soy bioactive compounds alongside the latest sustainable extraction methods designed to optimize their use. Future research should aim to refine fermentation and extraction processes, investigate synergistic microbial interactions, and develop environmentally sustainable production methods. These efforts have the potential to position fermented soy products as essential contributors to global nutritional security and sustainable food systems, addressing both public health and environmental needs.
Recent advances of machine learning in the geographical origin traceability of food and agro‐products: A review
Authors: Li Jiali , Qian Jianping , Chen Jinyong , Ruiz‐Garcia Luis , Dong Chen , Chen Qian , Liu Zihan , Xiao Pengnan , Zhao Zhiyao 
Published: December 2024

AbstractThe geographical origin traceability of food and agro‐products has been attracted worldwide. Especially with the rise of machine learning (ML) technology, it provides cutting‐edge solutions to erstwhile intractable issues to identify the origin of food and agro‐products. By utilizing advanced algorithms, ML can extract feature information of food and agro‐products that is closely related to origin and, more accurately, identify and trace their origins, which is of great significance to the entire food and agriculture industry. This paper provides a comprehensive overview of the state‐of‐the‐art applications of ML in the geographical origin traceability of food and agro‐products. First, commonly used ML methods are summarized. The paper then outlines the whole process of preparation for modeling, model training as well as model evaluation for building traceability models–based ML. Finally, recent applications of ML combined with different traceability techniques in the field of food and agro‐products are revisited. Although ML has made many achievements in solving the geographical origin traceability problem of food and agro‐products, it still has great development potential. For example, the application of ML is yet insufficient in the geographical origin traceability using DNA or computer vision techniques. The ability of ML to predict the geographical origin of food and agro‐products can be further improved, for example, by increasing model interpretability, incorporating data fusion strategies, and others.
Learning from the lived experiences of medical women working and studying at the national hospital in Fiji: A mixed methods study
Authors: Shankar Manisha L , Shailin Shivani , Phillips Georgina 
Published: December 2024

AbstractObjectiveOur study aimed to explore the experience of attaining higher education among women in medicine at the largest national hospital in Fiji, focusing on barriers and enablers to completing training, and to explore women's perception of gender‐based discrimination in the world of medicine. Findings subsequently informed evidence‐based recommendations on enablers and barriers at the hospital and medical university to improve experiences of women in medicine.MethodsWe conducted a mixed‐method study, emphasising the phenomenological qualitative component. All women doctors working at the national hospital were invited to complete a survey, and those with past or present engagement in postgraduate specialty medical training participated in semi‐structured interviews. Survey data were analysed using descriptive statistics. Interviews were transcribed, coded then organised using thematic analysis. Reflexivity and triangulation were employed at all levels of the research to ensure rigour.ResultsFour distinct themes were found to illuminate women's enablers and barriers. Participants described work‐life stress, absence of advocacy, coercion‐control‐power and inflexible systems as barriers. For enablers, they described inner strength, social circles, work culture and mentors/role models/advocates. Participants had mixed perspectives on gender‐based discrimination in the workplace, with unanimity in calling for protected maternity leave entitlements.ConclusionsChallenges only become true barriers when enablers are eclipsed by them. Institutional support helps mitigate these barriers especially for those women who lack social support. Gender based discrimination continues in the Pacific, commonly covertly, especially in terms of policy gaps regarding maternity leave during training.
Tepotinib for the Treatment of Lung Adenocarcinoma Harboring MET Y1003N Point Mutation: A Case Report
Authors: Umeda Yukihiro , Kimura Satomi , Kimura Junya , Imamura Yoshiaki , Ishizuka Tamotsu 
Published: December 2024

ABSTRACTThe mesenchymal‐epithelial transition factor (MET) Y1003 mutation, like MET ex14 skipping, is an oncogenic driver mutation that suppresses MET degradation. Herein, we report the case of a 63‐year‐old female patient with lung adenocarcinoma harboring the MET Y1003N mutation, who was treated with tepotinib, a selective type 1b MET tyrosine kinase inhibitor. To the best of our knowledge, no such cases have been reported. The woman was referred to our hospital with the chief complaint of chest pain. After a detailed examination, she was diagnosed with stage IVB lung adenocarcinoma. Next‐generation sequencing revealed an MET Y1003N mutation in the tumor. Tepotinib was administered as the eighth‐line treatment, and the best overall response was a partial response that lasted for 8 months. In lung adenocarcinomas harboring the MET Y1003 mutation, selective type 1b MET tyrosine kinase inhibitors may be an important treatment option, even in heavily pretreated settings.
Cordycepin ameliorates autoimmunity by promoting STING degradation via autophagy pathway
Authors: Yang Daidi , Peng Niannian , Zhang Hongqian , Qiu Zuocheng , Xu Lingxiao , Pan Mingyu 
Published: December 2024

AbstractBackground and PurposeStimulator of interferon response cGAMP interactor 1 (STING), a central hub protein of cyclic GMP‐AMP synthase (cGAS)–STING signalling pathway, has a crucial role in regulating type I interferons (IFNs) production and response. Recent studies indicate that excessive activation of STING is strongly associated with autoimmune diseases, including systemic lupus erythematosus (SLE). Searching immunomodulators that negatively regulate STING might greatly contribute to the suppression of autoimmunity.Experimental ApproachThe peripheral blood mononuclear cells (PBMCs) of SLE patients, Hela cells, L929 cells and bone marrow‐derived macrophages (BMDMs) from mice were used as in vitro models. While, Trex1 KO mouse autoimmune disease model was used as in vivo model. After treatment with cordycepin, a nucleoside from Cordyceps mushrooms, type I IFNs production and response were determined by western blotting, real‐time polymerase chain reaction (PCR), dual‐luciferase assay, enzyme‐linked immunosorbent assay (ELISA), haematoxylin–eosin staining and RNA‐seq.Key ResultsCordycepin inhibited type I IFNs production and response in human and murine systems following cGAS–STING signalling activation. Importantly, cordycepin markedly attenuates the autoinflammatory and autoimmune responses in Trex1 KO BMDMs and Trex1 KO mice. Furthermore, cordycepin effectively suppressed the production of type I IFNs and interferon‐stimulated genes (ISGs) in the PBMCs of SLE patients. Mechanistically, cordycepin promoted STING degradation via autophagy pathway upon DNA stimulation.Conclusion and ImplicationsThis study shows that cordycepin promotes STING autophagic degradation to alleviate autoimmunity upon DNA stimulation. Cordycepin might be a potential therapeutic candidate for alleviating aberrant type I IFNs in autoimmune and autoinflammatory diseases.
‘Can You Please Sit Still?!’: Exploring the Dynamics of Children's Sedentary Behaviours at Home
Authors: Rathod Apoorva , Olsson Jerry , Schwanen Tim 
Published: December 2024

ABSTRACTSedentary behaviour among children has become an area of interest in health research due to its associations with unfavourable health outcomes. Concerns about certain activities being sedentary guides much work in this field, with study outcomes often directed towards determining the amount of time spent in these activities. In this paper, we explore the idea of thinking about sedentary moments within children's everyday practices instead of total time spent in sedentary behaviours. Through this approach we examine children's everyday practices to show how activities by themselves should not necessarily be considered sedentary, but as composed of sedentary moments that are performed. We also look at how such sedentary moments are created, and the ways in which they are linked to material arrangements and pervasive understandings about how certain practices should be conducted. These could be seen as instruments of power acting upon the body, shaped by discourses about childhood and family life.
Evolution and Viability of Asian Horseshoe Crabs Appear Tightly Linked to Geo‐Climatic Dynamics in the Sunda Shelf
Authors: Tang Qian , John Akbar , Wardiatno Yusli , Nishida Shin , Van Tu Do  , Xie Xiaoyong , Pati Siddhartha , Susanto Handoko Adi , Hajisamae Sukree , Nelson Bryan Raveen , Min Wah Wah , Hasan Mohammad Eusuf , Salles Tristan , Chen Yilin , Qu Yanhua , Lei Fumin , Venkatesh Byrappa , Rheindt Frank E. 
Published: December 2024

ABSTRACTHorseshoe crabs are unique living fossils that have remained almost unaltered through 400 million years of global change. They face rapid worldwide declines under increasing anthropogenic pressure. Using comprehensive geographic and genomic sampling combined with approaches that integrate DNA with environmental and climatic datasets, we assessed the population genetic structure, demographic histories, and vulnerability to future climate change in three out of four extant horseshoe crab species, all centered in Asia. Our study highlights that the Sunda Shelf, a complex and dynamic shallow‐marine landscape, has been the sole repository of most genetic diversity among all three Asian species, and therefore crucial to the long‐term survival of horseshoe crabs. Our study not only provides the first genomic baseline data for the evaluation of Asian horseshoe crabs’ conservation status but also identifies core habitats that potentially act as refugia and corridors for Asian horseshoe crab populations with impending anthropogenic global warming.
The role of brain oscillatory activity in processing the informative value of feedback during rule acquisition
Authors: Liu Fangfang , Li Fuhong , Du Bin 
Published: December 2024

AbstractInformation conveyed through feedback enables individuals to learn new routines and better adapt to their environment. However, the neural mechanisms of rule‐related information of feedback have not been fully elucidated. Herein, we quantified the effect of informative value on feedback via a rule induction task (RIT), in which participants were required to find the correct sorting rule based on feedback. To disengage the effects of informative value and valence on feedback in the RIT, a control task was developed in which feedback only involved the valence aspect and no reference for subsequent selections. We measured power and intertrial phase clustering (ITPC) values via EEG to determine the neural mechanisms of rule‐related feedback. The results revealed that (1) differences in oscillatory activities between positive and negative feedback were only observed during the control task, and no such effect was found in the RIT task. This finding suggests that the participants paid more attention to rule‐related information than to the correctness of feedback during rule learning. (2) The task differences under positive or negative feedback were associated with the delta‐theta and alpha‐beta bands, and this pattern was similar within the frontal and parietal regions. These findings suggest that the processing of rule‐related information of feedback relies on broad frequency bands within the frontoparietal cortex to facilitate rule information integration. In summary, these findings indicate that multiple frequency bands are involved in encoding the informative value aspect of feedback, and individuals rely on this aspect of feedback rather than valence during rule learning.
TSPO‐PET in pre‐surgical evaluations: Correlation of neuroinflammation and SEEG epileptogenicity mapping in drug‐resistant focal epilepsy
Authors: Kilmer Jennifer , Rodrigo Sebatian , Petrescu Ana‐maria , Aghakhani Nozar , Herbrecht Anne , Leroy Claire , Tournier Nicolas , Bottlaender Michel , Taussig Delphine , Bouilleret Viviane 
Published: December 2024

AbstractObjectivesResective surgery in drug‐resistant focal epilepsy (DRFE) requires extensive evaluation to localize the epileptogenic zone (EZ). When non‐invasive phase 1 assessments (electroencephalography, EEG; magnetic resonance imaging, MRI; and 18F‐Fluorodeoxyglucose–positron emission tomography, [18F]FDG‐PET) are inconclusive for EZ localization, invasive investigations such as stereo‐EEG (SEEG) are necessary. Epileptogenicity maps (Ems) visualize the EZ using SEEG‐identified ictal high‐frequency oscillations (iHFOs). PET imaging with radioligands targeting the18‐kDa translocator protein (TSPO), a marker of glial activation, may aid EZ localization. This study investigates the correlation between TSPO‐PET imaging and SEEG iHFOs in DRFE to determine the utility of TSPO‐PET in pre‐surgical assessments, especially in complex or non‐lesional cases.MethodsPatients with DRFE and inconclusive phase 1 assessments were recruited from Bicêtre Hospital (AP‐HP) for a prospective study (Eudract 2017–003381‐27). They underwent SEEG and [18F]DPA‐714 (N,N‐diethyl‐2‐(2‐(4‐(2‐(fluoro‐18F)ethoxy)phenyl)‐5,7‐dimethylpyrazolo[1,5‐a]pyrimidin‐3‐yl)acetamide) (TSPO radioligand) PET imaging. Statistical parametric mapping (SPM) techniques analyzed significant [18F]DPA‐714‐PET uptake (TSPO‐map) and generated epileptogenicity maps (EM‐map). Correlation analyses at regional and voxel‐of‐interest (VOI) levels assessed the relationship between TSPO‐map and EM‐map.ResultsWe were able to obtain and analyze both maps in 12 of 17 patients recruited. A significant positive correlation between EM‐map and TSPO‐map in focal epilepsies was found regionally (r = .81, p < .00004) and at the VOI level (r = .79, p < .00003). Temporal, insular, parietal, and occipital regions showed particularly strong correspondence. In frontal epilepsies, TSPO‐map was more focal than EM‐map, suggesting increased specificity for SEEG planning. This study also demonstrated the benefit of the TSPO‐map in identifying multiple foci in multifocal epilepsies, with or without lesions.SignificanceThese findings suggest that neuroinflammation may be a molecular substrate of the EZ in non‐lesional focal epilepsy. Identifying the EZ inpatients with complex DRFE and inconclusive MRI/[18F]FDG‐PET imaging is essential to improve resective surgery outcomes. Combining TSPO‐PET imaging with SEEG recordings may help bridge this gap.