bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantification of safe operation conditions for large-area platinum-iridium electrodes in neurostimulation application
Authors: Leusmann Elisa , Abkai Ciamak , Tittelbach Michael , Poppendieck Wigand 
Published: December 2024

Objective
Using electrochemical characterization methods of stimulation electrodes as well as accelerated stimulation examinations, a safe operating field for stimulation is investigated for particularly very large Pt-Ir macroelectrodes in a Laplace configuration.

Approach
Traditional methods such as Electrochemical Impedance Spectroscopy, Cyclic Voltammetry and biphasic, charge balanced current pulses were applied on Pt-Ir macroelectrodes in phosphate buffered saline solution to investigate reversible boundaries. These experiments were adapted to approach realistic working conditions.

Main results
Investigating operational conditions close to realistic use cases have shown an anti-correlation between higher scan rates and the occurrence of irreversible reactions. In addition, at higher current pulse amplitudes (>3 mA), the voltage dropping across the phase boundary (Ema and Emc) saturated. The value of the residual voltage depends on the degree of charge balance of the biphasic pulse. Thus, we have been able to detect more dissolved platinum at high residual voltages—objected by mass spectroscopic measurement.

Significance
Residual voltage plays a greater role concerning reversibility in prolonged stimulation and charge imbalance of applied biphasic current pulses. The Ema saturation is suggested as a new marker for the occurrence of irreversible reactions which needs further investigation. Current amplitudes of 1 mA for the considered single electrode configuration did not lead to a capacitive voltage saturation nor a considerable dissolution of platinum ions and is thus considered as a safe operation configuration.
La Formación del Profesorado para Ejercer la Dirección de Centros Educativos
Authors: Tesouro Cid Montserrat , Puiggalí Allepuz Joan 
Published: December 2024

En la formación de los/las directores/as escolares es importante saber cuándo, cómo, de qué tipo debe ser la formación y quién la debe impartir. Se utiliza una metodología cuantitativa no experimental para conocer la opinión de los profesionales de la educación sobre la formación de directivos/as. Se elaboró un cuestionario de opinión ad hoc que fue contestado por una muestra de 530 profesionales de la educación de España. Los resultados muestran que se da tanta importancia a la formación previa al acceso al cargo como a la formación permanente. Las modalidades formativas más consideradas son las conferencias o cursos impartidos por expertos y las mentorías o coaching. Las conferencias o cursos son más aceptados por la Administración Educativa y por los/las directores/as mientras que la mentoría o coaching es la modalidad más escogida por los que no tienen experiencia en el cargo. Las herramientas más valoradas son el análisis de casos y la resolución de problemas y los profesionales más adecuados para impartir la formación son los/las directores/as en ejercicio. Se concluye que la mejora de la formación debería tener un carácter más práctico y que es importante el factor experiencia que pueden aportar los/las directores/as en ejercicio. También se observa la importancia de la mentoría o coaching para aquellos que no han ejercido o para los directores noveles.
Development of an Inclusive Demographic Survey for Clinical Care and Research
Authors: Nguyen-Kearns Elizabeth , Burgara Jacqueline , Hajikedir Dureti , Nguyen Tommy , Wingfield Elizabeth , Liljenquist Kendra , Desai Arti D. 
Published: December 2024

BACKGROUND AND OBJECTIVES
There is a need to accurately capture family demographic information to ensure appropriate delivery of services, optimize patient experiences, and examine health disparities; however, we lack a standardized and inclusive approach to collect demographic data. Our objective was to design a set of inclusive survey items for common demographic categories that can be used for clinical care and research.

METHODS
In this prospective, mixed-methods study, we used a rigorous survey design approach to conduct a literature review, seek expert validation, and perform cognitive pretesting with families between October 2021 and September 2023 to iteratively develop an inclusive demographic survey. Survey iterations were made based on triangulation of rankings for each candidate survey item and content analysis of feedback from content experts and families.

RESULTS
We incorporated 21 sources from the literature review, feedback from 7 content experts, and cognitive pretesting data from 57 patient and family respondents from diverse backgrounds. We developed a final survey assessing the following categories: gender identity and sex (2 items), race and ethnicity identity (1 item), language for care (4 items), household education (1 item), and household socioeconomic status (1 item). The final survey captures nuances in demographic information (eg, racial and ethnic identity) within a parsimonious survey structure and optimizes the use of respectful, inclusive language.

CONCLUSIONS
We used a rigorous, family-centered survey design approach to develop a novel inclusive demographic survey, providing a standardized tool for comprehensive and accurate demographic data collection in clinical care and research.
Descolamento prematuro de placenta e útero de couvelaire
Authors: Sousa Bruna de Cássia , Barros Ana Carolina Beghini , Moura Elisa Coutinho 
Published: December 2024

O descolamento prematuro da placenta representa a separação precoce da placenta da parede do útero. De forma patológica, ocorre enquanto o feto ainda está no útero, podendo incorrer em mortalidade fetal, prematuridade e morbidade materna. O útero de Couvelaire é um extravasamento de sangue que se infiltra na parede uterina. Como resultado, a musculatura miometrial não consegue se contrair adequadamente e, assim, causa sangramento pós-parto. Este é um relato de caso de uma paciente com 32 semanas de gestação portadora de doença hipertensiva específica da gestação sem uso de medicação e tabagista, que se apresentou no hospital com dor abdominal e cefaleia frontal, sem perdas de líquido ou sangramento. A paciente recebeu o diagnóstico de óbito fetal e descolamento prematuro de placenta após ultrassonografia obstétrica. Após expulsão fetal, paciente evoluiu com atonia uterina e hemorragia puerperal de difícil controle, sendo necessária histerectomia e constatado útero de Couvelaire à visualização uterina.
The Challenges of the First-Year Student in Higher Education Institutions in Cambodia
Authors: Chantrea MOEURN , Chanphirun SAM , Sarom MOK 
Published: December 2024

In the 1990s, the Royal Government of Cambodia (RGC) initiated the privatization of higher education institutions (HEIs. This policy shift led to a dramatic increase in the number of HEIs, expanding from only 8 in the late 1990s to 189 in the academic year 2022–2023. Alongside this growth, students’ enrollment number surged from 175,962 in the academic year 2021–2022 to 237,243 in 2022–2023. The transition from secondary to higher education represents a significant change for students. Currently, there is not many research studies that mainly focus on the first – year student challenges in higher education in Cambodia. This qualitative research aims to explore the challenges faced by first-year students in Cambodia’s HEIs. A semi-structured interviews was selected with the participants purposively selected from six public and private HEIs. In sum, there are fifty-seven participants in total from the six HEIs and other relevant institutions to contribute to the study. The findings indicate that first-year students encounter several challenges such as academic challenges, personal challenges, social integration challenges, transition to career-oriented learning challenges, and adaptation to available student services challenges. The results underscore the need for HEIs to prioritize creating a supportive environment that fosters a smooth transition, encouraging student retention and continuity into subsequent years.
Sustentabilidade nas Universidades: uma abordagem a partir dos marcos legais e históricos na perspectiva da sociedade informacional e alta modernidade
Authors: Barros Bruno Mello Correa de , Beuron Corrêa de Barros Thiago Antônio , Garlet Valéria 
Published: December 2024

A ideia de sustentabilidade em meio à sociedade emerge da necessidade de conscientização da escassez dos recursos naturais, e da sua relação com a satisfação das necessidades das gerações atuais e do futuro. Em meio a isso, algumas organizações são capazes de propor e promover reformas culturais profundas, criando assim um ambiente propício para a difusão de princípios sustentáveis, e entre elas estão as instituições de ensino e as universidades. O objetivo do estudo é resgatar os marcos regulatórios que contribuíram para uma nova dinâmica da sustentabilidade em meio à sociedade brasileira, bem como resgatar os principais eventos que envolveram a temática no contexto das universidades e publicações acerca do tema. Como método, o trabalho possui uma técnica indireta de tratamentos dos dados, visto que foi utilizado o levantamento bibliográfico. Em relação ao procedimento, o método usado foi o monográfico e comparativo, e o cunho exploratório e qualitativo, visto que possibilita a interação e percepção maior do tema estudado. Como resultados, percebe-se que a discussão acerca do desenvolvimento sustentável em universidades é tema cada vez mais recorrentes em diferentes áreas do conhecimento. Através das universidades, é possível discutir e incentivar a transformação da sociedade para a prática de ações mais sustentáveis, bem como a propagação de competências e comportamentos capazes de promover a sustentabilidade no meio acadêmico, e ampliar suas ações à sociedade.
Análisis comparativo de la política lingüística educativa de Paraguay y Colombia
Authors: Rotela Riveros Guadalupe del Carmen 
Published: December 2024

Este documento muestra las semejanzas y diferencias que existen entre las políticas lingüísticas educativas en Paraguay y Colombia. Se realizó una revisión exhaustiva de los lineamientos propuestos por los ministerios de Educación de ambos países en el campo lingüístico, con el fin de hacer un análisis comparativo, específicamente de las políticas relacionadas con el proyecto de bilingüismo. Las semejanzas en ambos países se refieeren a la metodología activa y participativa en el aprendizaje, como la equidad, planificación, enfoque en el contexto del alumno y diversidad, en busca de afianzar los procesos de identidad, conocimiento, socialización y protección de las lenguas autóctonas. En cuanto a las diferencias, en el Paraguay existe el aprendizaje de una lengua indígena (el guaraní) para preservar la lengua autóctona, mientras que en el caso de Colombia se hace hincapié en la enseñanza del inglés como lengua extranjera.
Counseling on the Dangers of Repeated Use of Cooking Oil and Training on the Valorization of Used Cooking Oil for Dorokdok Cracker Producer in Suci Village
Authors: Fauziah Nenden , Prasetiawati Riska , Senania Astri , Apriani Riza , Annisa Rahmasari Kanto Dhini 
Published: December 2024

Producers of cowhide crackers (dorokdok) in Suci Village have the potential to produce cooking oil waste of more than 1 ton/week. In addition, cooking oil is often used repeatedly to reduce production costs. From situation analysis and field observations, the people of Suci Village do not yet know the dangers of using used cooking oil repeatedly and how to process used cooking oil into biodiesel. This service activity aims to educate the public about the dangers of repeated use of used cooking oil and the valorization of used cooking oil into biodiesel. It is hoped that the step of valorizing used cooking oil can prevent repeated use of cooking oil without having an impact on increasing dorokdok production costs. The method of implementing service is counselling and training. Changes in community knowledge are evaluated through the implementation of pretests and posttests. The evaluation results show an increase in public knowledge about the dangers of repeated use of cooking oil and steps to valorize used cooking oil reaching 66.20%. It is hoped that the step to valorize used cooking oil will be a way to create a healthy environment and food as well as realize economic independence in Suci Village.
TERMINOLOGIA DA MATEMÁTICA EM LÍNGUA DE SINAIS BRASILEIRA: PROPOSTA DE GLOSSÁRIO BILÍNGUE LIBRAS PORTUGUÊS
Authors: Rodolpho Pinheiro D’ Azevedo  
Published: December 2024

O tema desta dissertação se insere na linha de pesquisa Léxico e Terminologia, desenvolvida no Centro de Estudos Lexicais e Terminológicos (Centro Lexterm) e no Laboratório de Língua de Sinais Brasileira (LabLibras) da Universidade de Brasília. Oobjeto de estudo é constituído pelos termos matemáticos relacionados ao campo conceitual equações, tendo como públicoalvo os alunos Surdos, bem como os professores e intérpretes educacionais atuantes na Educação Básica. O objetivo é criar glossário terminológico bilíngue Libras-Português de termos matemáticos deste campo conceitual. Para tanto, registramos os termos e sinais-termo seguindo o modelo de ficha terminográfica de Faulstich (2010), para a Língua Portuguesa – LP, e o modelo de ficha terminográfica em Libras de Tuxi (2017). O método empregado na pesquisa foi o analítico-descritivo. Como procedimentos metodológicos, adotamos os seguintes percursos: i) coleta dos termos e das definições em LP; ii) reformulação das definições em LP; iii) preenchimento das fichas terminográficas em LP; iv) coleta dos sinais-termo em Libras; v) criação dos sinais-termo; vi) validação dos sinais-termo; vii) preenchimento das fichas de análise de sinal-termo; viii) criação das definições em Libras e ix) preenchimento das fichas terminográficas em Libras. Para o preenchimento das fichas de análise de sinal-termo e das fichas terminográficas em Libras utilizamos QR Code (TUXI, 2017) para disponibilizar a visualização dos sinais-termo, definições, variantes, equivalentes e remissivas por meio de vídeos. Realizamos, ainda, a análise de sete obras terminológicas da matemática com base no roteiro para avaliação de dicionários e glossários científicos e técnicos de Faulstich (2011). Dentre as obras avaliadas, as línguas contempladas foram português, inglês, Libras, ASL, BSL e LSF. Além disso, analisamos as definições matemáticas contidasnos livros didáticos aprovados pelo PNLD utilizados do 6° Ano do Ensino Fundamental ao Ensino Médio. Essa análise revelou a necessidade de reformulação das definições em língua portuguesa. Como resultado dessa pesquisa, apresentamos o glossário bilíngue Libras – Português da matemática, o qual se baseou na proposta de organização de glossário bilíngue de Tuxi (2017). No glossário bilíngue Libras – Português de matemática são apresentados os 30 verbetes no formato bilíngue Libras – Português de 30 termos e sinais-termo do campo conceitual equação. Ainda, apresentamos a proposta de registro de sinais-termo equivalentes em outras línguas de sinais, além da possibilidade de direcionamento a remissivas, tanto em LP quanto em Libras, por meio de hiperlinks. A contribuição da pesquisa é disponibilizar obra de consulta, direcionada aos alunos Surdos, professores e intérpretes educacionais. Além disso, o modelo de glossário apresentado pode servir para ser aplicado em outros campos conceituais ou a outros domínios do saber.
Assessment of users’ skills in managing electronic records management system at Workers Compensation Fund (WCF) Dar Es Salaam, Tanzania
Authors: Maturo Bertha 
Published: December 2024

This study assessed users' skill in operating the electronic records management system, specifically concerning the Workers Compensation Fund (WCF). The study specifically examined the training for the electronic records management system, encompassing the types of training offered, their frequency, and the relevance and effectiveness of the training delivered. The study population consisted of all employees at WCF. The study deployed a descriptive research design in conjunction with qualitative and quantitative methodologies. The sample size consisted of 115 respondents. Data were gathered by questionnaires, interviews, and observational methods. Additionally, qualitative data were quantitatively evaluated using IBM-SPSS version 20, along with Microsoft Word and Excel, to ascertain the frequency and percentage of respondents' replies in relation to the study findings. Findings indicated that WCF offers operational training for ERMS, while security and technical training for ERMS staff is conducted annually to enhance employees' abilities and expertise in administering ERMS. The study indicates that the management of WCF should continue to empower the ICT team to provide comprehensive in-house support. Additionally, negotiate with EGA for a dedicated desk to address their technical difficulties.
Stationary Distribution of Stochastic SEIRS Epidemic Model with Saturated Incidence Rate and Saturated Treatment Function
Authors: S Saravanan , C Monica 
Published: December 2024

يهدف هذا البحث إلى تعزيز وتوسيع النموذج الرياضي الذي يحكم وباء SEIRS العشوائي الديناميكي (المعرض والمكشوف والمعدي والمعافى). يدمج هذا النموذج المعقد مكونات حاسمة، بما في ذلك معدل الإصابة المشبع و دالة العلاج المشبعة، والتي تعتبر أساسية في تشكيل ديناميكيات الوباء. الهدف هو استكشاف وجود و وحدانية الحل العالمي الإيجابي من خلال تطبيق وظيفة Lyapunov المصممة بدقة، مما يسهل إجراء تحليل أكثر عمقا لتعقيدات الأنظمة. يمكّننا هذا الإطار التحليلي من الكشف عن التفاعلات بين انتقال المرض وديناميكيات العلاج والتأثيرات العشوائية. ضمن هذا الإطار النظري، يفترض أن الاستجابة للعلاج تتناسب طرديا مع عدد الأفراد المصابين طالما بقيت حالات الإصابة داخل نظام الرعاية الصحية. يكمن أحد الجوانب الرئيسية لمساهمتنا في تحديد رقم التكاثر الأساسي العشوائي باعتباره عتبة حرجة تحدد مسار الوباء. في ظل الظروف التي تتميز بمستويات ضوضاء منخفضة و ، فإنه يحدد المتطلبات الأساسية لظهور توزيع ثابت مريح، ويقدم نظرة ثاقبة للاتجاهات المحتملة طويلة المدى في انتشار المرض. وعلى العكس من ذلك، في السيناريوهات التي تتميز بكثافة الضوضاء العالية ، يلقي تحليلنا الضوء على الاستئصال الحتمي للمرض. ولزيادة تعزيز الأسس النظرية، يدمج بحثنا عمليات محاكاة رقمية واسعة النطاق. لا تؤكد عمليات المحاكاة هذه صحة النتائج النظرية التي توصلنا إليها فحسب، بل توفر أيضًا تصورًا ديناميكيًا لآثار النموذج. تساهم هذه المنهجية المزدوجة، التي تجمع بين الفحص النظري الدقيق وعمليات المحاكاة العملية، في فهم دقيق لدور العشوائية في تشكيل ديناميكيات الوباء.
Loss of ARID1A leads to a cold tumor phenotype via suppression of IFNγ signaling
Authors: Freeman Kevin , Watson Pamela , DeVaux Chelsea 
Published: December 2024

Abstract

The collapse of inflammatory signaling that recruits cytotoxic immune cells to the tumor microenvironment contributes to the immunologically cold tumor phenotype in neuroblastoma (NB) and is a barrier to NB immunotherapy. Multiple studies have reported that MYCN amplification, a trait of high-risk NB, correlates with a loss of inflammatory signaling; but MYCN also correlates with 1p36 deletions in NB where the SWI/SNF chromatin remodeling complex subunit ARID1A (1p36.11) is located. ARID1A is known to support inflammatory signaling in adult cancers but its role in NB inflammatory signaling is unexplored. We find MYCN overexpression causes a stronger and ARID1A knockdown causes a weaker inflammatory response to interferon-gamma (IFNγ). ARID1A silencing reduces IFNγ induced gene signatures for the transcription factor interferon response factor 1 (IRF1). We found ARID1A is a functional interactor of IRF1 by co-immunoprecipitation studies, and ARID1A silencing causes loss of activating chromatin marks at the IRF1 target gene CXCL10. We model that IRF1 uses ARID1A containing SWI/SNF to promote IRF1’s target genes in response to IFNγ. This work finds that ARID1A is a critical regulator of inflammatory signaling in NB and provides rationale for testing immune therapies in MYCN amplified NB that are effective in adult ARID1A mutated cancers.
Community-Engaged Research on Water Quality Analysis and Environmental Risk Zone (ERZ) Mapping using GIS and Neuro- Fuzzy Models in Ramanathapuram District, Tamil Nadu, India
Authors: A Stanley Raj , Angelena J. P. , Roy Ronald Win , Pious Joseph , Jobisha J. , Fredrick A. , Selvan C. Tamil , Oliver Hudson 
Published: December 2024

Abstract

Water, a basic amenity and universal solvent, is utilized by the population. Physicochemical analysis of the Ramanathapuram district of Tamil Nadu was performed to evaluate its suitability for potable purposes. The quality of groundwater was determined through the analysis of pH, electrical conductivity, sulfate content, nitrate content, total hardness, calcium content, magnesium content, sodium content, and total dissolved solids. The results were computed and compared with WHO and BIS water quality standards. In several regions, the permissible limits of electrical conductivity, sulfate, nitrate, magnesium, total hardness, and other parameters were exceeded. High concentrations of these parameters may be attributed to urbanization, saline water intrusion, and the influence of sewage. The obtained results suggest the need for regular monitoring of groundwater quality in this study area to prevent further contamination. A neurofuzzy weighted algorithm was applied to assign weights to each geochemical parameter, culminating in an environmental risk zone assessment. This emphasizes the critical need for ongoing evaluation and proactive measures to ensure the safety and sustainability of groundwater resources in the region. The current research is validated with the field data collected from local community people of Ramanathapuram district. This research portraits the current scenario of groundwater in the study area and it necessitates the government to take measures, awareness and policies related to the improvement of groundwater quality.
Why do rural residents in China withdraw from the health insurance system? —A Qualitative Study Based on Y County in S Province, China
Authors: Zuo Ying , Yang Guang , Cheng Haoxuan , Zhang Lufa 
Published: December 2024

Abstract

Background:Since the 2009 healthcare reform, the Chinese government has been committed to establishing a universal healthcare system. This study aims to investigate the complex reasons behind the decision of rural residents in China to forgo participation in the medical insurance system by examining causal relationships and interactions.
Methods: This study employs content analysis, conducting in-depth interviews with 42 stakeholders, including government administration departments, tax departments, medical insurance departments, village committees, and residents who have not enrolled in the medical insurance.
Results: The study finds that the primary reasons for rural residents withdrawing from medical insurance are fourfold: heavy economic burdens, unfair design of the medical insurance system, failure of conventional mobilization strategies, and cognitive biases fostered by the internet.
Conclusion: The decision of rural residents in China to withdraw from medical insurance is influenced not only by economic factors but also by the design of the system and various aspects of rural governance. In the future, the Chinese government should optimize the design of the medical insurance system, adopt more flexible mobilization and persuasion strategies, and strengthen the control of negative internet rhetoric to stimulate enthusiasm for participation in medical insurance among rural residents, thereby advancing the universal health strategy.