bluuebunny/crossref_metadata_2025_split huggingface dataset:
The ER stress-autophagy axis: implications for cognitive dysfunction in diabetes mellitus
Authors: Zhu Qingzhang 
Published: June 2020

Abstract
Unfolded protein response (UPR) often coordinates with autophagy to maintain cellular proteostasis. Disturbance of proteostasis correlates with diseases including diabetes and neurological complications. In a recent article in Clinical Science, Kong et al. highlighted the critical role of endoplasmic reticulum (ER) stress-autophagy axis in maintaining cognitive functions and provided pharmacological evidence with respect to cognitive improvements in a diabetic mouse model. These novel findings present new insights into the pathological mechanisms and therapeutic implications with the ER stress modulators in diabetes-related cognitive dysfunction.
Spindle scaling mechanisms
Authors: Krüger Lara K. , Tran Phong T. 
Published: June 2020

Abstract
The mitotic spindle robustly scales with cell size in a plethora of different organisms. During development and throughout evolution, the spindle adjusts to cell size in metazoans and yeast in order to ensure faithful chromosome separation. Spindle adjustment to cell size occurs by the scaling of spindle length, spindle shape and the velocity of spindle assembly and elongation. Different mechanisms, depending on spindle structure and organism, account for these scaling relationships. The limited availability of critical spindle components, protein gradients, sequestration of spindle components, or post-translational modification and differential expression levels have been implicated in the regulation of spindle length and the spindle assembly/elongation velocity in a cell size-dependent manner. In this review, we will discuss the phenomenon and mechanisms of spindle length, spindle shape and spindle elongation velocity scaling with cell size.
Reduced voltage stress hybrid multilevel inverter using optimised predictive control
Authors: Khandelwal Yash , Routray Abhinandan , Singh Rajeev Kumar , Mahanty Ranjit 
Published: June 2020

This study presents a hybrid multilevel inverter (HMLI), capable of generating 19 voltage levels using a single DC voltage source. The peak inverse voltage of all the switches is restrained within the input DC source voltage in the proposed HMLI, which requires only three capacitors and 15 switches to achieve 19 voltage levels. In the proposed HMLI, one of the capacitors is self‐balanced, while the other two capacitors are balanced using a modified finite control set model predictive control (MFCS‐MPC). The proposed MFCS‐MPC reduces the computation time considerably without affecting the performance of the system. The proposed HMLI is compared with some other HMLI topologies to show its merits in terms of active and passive components. Finally, the steady‐state and dynamic performance of the proposed topology and its control algorithm is validated through simulation and experimentation for a 1 kW prototype.
Wechselwirkungen zwischen bioaktiven Sekundärmetaboliten und
Irinotecan
Authors: Kronabel Dieter 
Published: June 2020

ZusammenfassungIrinotecan wird seit mehr als zwei Jahrzehnten in unterschiedlichen
Arzneiformen, auch in Kombination mit anderen Arzneistoffen, zur Behandlung
einiger Tumorerkrankungen eingesetzt. Irinotecan, ein Prodrug, wird
über die Butyrylcholinesterase und über die
Carboxylesterasen CES1 und CES2 in die aktive Form SN-38
(7-Ethyl-10-hydroxycamptothecin) verstoffwechselt. SN-38 ist ein starker
Topoisomerase-I-Inhibitor. Aufgrund des komplexen Metabolisierungsweges von
Irinotecan und wegen der engen therapeutischen Breite des Arzneistoffes ist
die klinische Relevanz einer Interaktion zwischen bioaktiven
Sekundärmetaboliten und Irinotecan von vielen unterschiedlichen
Einflussfaktoren abhängig und kann daher nur im Rahmen einer
individualmedizinischen Betreuung Bedeutung haben. Sowohl die
Butyrylcholinesterase und die Carboxylesterasen CES1, CES2 als auch CYP3A4,
CYP3A5, UGT1A-Isoforme und Transportproteine sind an der Verstoffwechselung
und Eliminierung von Irinotecan beteiligt und limitieren die
Verfügbarkeit des aktiven Metaboliten SN-38. Inhibition oder
Induktion dieser Enzyme durch bioaktive Sekundärmetabolite
könnten die therapeutische Wirksamkeit des Irinotecan-Metaboliten
SN-38 beeinflussen und für die Ausbildung von Nebenwirkungen
ursächlich sein. Der folgende Artikel versucht, einige
mögliche Interaktionen abzuschätzen und aufzuzeigen.
At the intersection of quantitative and qualitative
Authors: Caristia Stefania 
Published: June 2020

Abstract
This chapter discusses methodological issues related to the quantitative analysis of translations
in periodical publications and the possibilities to conjugate quantitative and qualitative approaches. I will propose
a model for a weighted analysis of translations in periodicals as well as the first results of its application on a
heterogeneous corpus of nine-teen Italian literary and political-literary periodicals of the post
Second World War period (1944–1970). Building on a systematical analysis of the networks of Italian periodicals, this
method takes into account some fundamental characteristics in the life of periodicals, and in particular their
diffusion and their symbolic capital in the literary field. It thus quantitatively measures qualitative phenomena.
Eternal problems
Authors: De Clerck Ernest 
Published: June 2020

Abstract
This chapter contends that literatures cannot solely be considered within national frameworks.
This is illustrated by a case study of the transnational dimensions of Stendhal’s work in British Late-Romantic
literary magazines. The Late-Romantic period is often seen as an insular, self-reflexive period within British
Romanticism. Evidence shows, however, that it was a truly international period with literature continually crossing
the channel in different forms. Three of the major literary magazines of the period played an important role in this
transnational literary exchange: The New Monthly Magazine, the London Magazine, and
Blackwood’s Edinburgh Magazine. This article focuses on the polemical, competitive, and
ideological struggles between the three magazines, exemplified in the way they treated the French author Stendhal,
through translation and reception.
Photoacoustic Research Development in Industrial Era 4.0
Authors: Mitrayana  , Satriawan M 
Published: June 2020

Abstract
Photoacoustic (PA) is the phenomenon of changing optical power into acoustics (sound). Photoacoustic research continues to grow and have broader field of application, especially after the development of laser technology and the development of laser diodes. In the industrial era 4.0, PA research is increasingly developing, especially in the PA tomography topics or PA imaging which is widely applied in medicine, as well as in single molecular imaging research and the 3D imaging of body tissue system.
Development of Magnetic Materials Based on Micro-Nano Particles Natural Ferrite as Microwaves Absorber Materials
Authors: Mashuri  , Heni D B 
Published: June 2020

Abstract
Ferrite-based magnetic materials (ferrites) can be simple iron oxide compounds such as Fe2O3 or Fe3O4, and similar compounds containing other cations besides iron, such as BiFeO3, CaFe 4O7, and BaFe12O19. The solid phase of these compounds generally has varying magnetic properties, depending on the cation (A+m) which is the substitution of the iron cation (Fe+3) in its crystal structure. In addition to the magnetic properties of interest, the compound in question also has strong absorption properties in electromagnetic waves in the frequency interval of 1 - 20 GHz (microwave), which is commonly used in the world of communication and radar technology. With these properties it is possible to develop these materials for electromagnetic shielding and stealth technology applications. As a magnetic element, ferrite material requires a conductive reflector element, to form a “core - shell” or “matrix - filler” system which results in absorption properties. The research that has been developed is in the form of Fe3O4 based micro-nano magnetic powder made from natural ferrite (iron sand). The sythesized of magnetic micro-nano particles using chemical extraction-milling and coprecipitation methods. Morphology of micro-nano particles ferrites has been confirmed by using SEM and TEM. The results of measurements of absorption of microwaves using a Vector Network Analyzer showed that the ferrite nano particle powder has greater absorption power (Reflection Loss < - 20 dB) than micro particle powders with ≥ 99 % absorption in the “X-band” region. The extraction-milling method is simpler and more economical than the chemical coprecipitation method so that it is suitable to be an alternative method for producing large-scale ferrite powder.
Effectiveness of Project Based Laboratory Learning to Increase Student’s Science Process Skills and Creativity
Authors: Dwikoranto  , Munasir  , Setiani R , Suyitno  , Surasmi W A , Tresnaningsih S , Pramonoadi  
Published: June 2020

Abstract
The Project Based Laboratory Learning (PJBLL) model is an innovative physics teaching model designed to enhance student’s sciences process skills and creativity. Therefore, this research aims to analyze the effectiveness of PJBLL model to improve sciences process skills and creativity physics students who were programmers in Unesa’s laboratory. The study design used one-group pretest-posttest design. Data collection methods were conducted by using tests sciences process skills and creativity. Data is analyzed using Paired t-test and N-gain. The results of the study show that there was a significant increase in student’s sciences process skills and creativity at α = 5% with N-gain average of moderate category. Thus, the PjBLL model is effective for enhancing student’s sciences process skills and creativity.
Magnetic Properties of FePt Material Influenced by Heat-Assisted Using Micromagnetic Simulation
Authors: Rohman L , Purwandari E , Romadhony I , Djuhana D 
Published: June 2020

Abstract
Platinum (FePt) is a ferromagnetic material that has a Face Centered Cubic (FCC) crystal structure. FePt material is classified as a hard magnetic material that can be applied as a magnetic storage medium. The composition of the material used in this study was Fe0.85Pt0.15. This study examined the magnetic properties of nano-sphere shaped FePt materials against the coercivity fields under the effect of heat-assisted variations in laser power values. The difference in magnetic properties due to the influence of laser power was seen based on the hysteresis curve. Micro-magnetic simulations were carried out to obtain Curie-temperature values, hysteresis curves, and configuration of the direction of spin of FePt material. This simulation found the Curie-temperature of the material as 650 K. The direction of the magnetization reversed by the power laser-assisted so quickly. With a small coercivity field; magnetic recording media can carry out the writing and recording process in high capacity. Based on the simulation results, laser power that has the potential to be applied to Fe0.85Pt0.15 material. When the computer works at temperatures 0 K, the laser power 0 W to 0.0026 W can be applied. We use the suitable laser power 0 W to 0.016 W at temperatures of 298 K and 318. While the temperature of 339 K cannot be applied with laser power because it gets an overheat temperature.
Metacognitive Learning Strategy with Reflective-Lesson Log Toward Students’ Physics Achievement
Authors: Silitonga H T M , Sutiana W , Panjaitan M , Supriyati Y 
Published: June 2020

Abstract
The study examined the effect of metacognitive learning strategies with a reflective-lesson log toward students’ physics achievement on Senior High School. The research employed the experimental method used groups within treatment designs and conducted at SMAN 4 and SMAN 7 Pontianak involving 117 students taken randomly through cluster random sampling technique. Data analysis was performed by comparing the post-test of students who studied by metacognitive strategies and students who studied by traditional teaching. Data were analyzed using the t-test. The result showed that the students’ physics achievement who studied by metacognitive strategy with a reflective-lesson log was higher than students’ by traditional strategy. Thus, it was recommended that physics senior high schools’ teachers could implement the metacognitive strategy with a reflective-lesson log as one of innovation physics teaching.
The Use of Virtual Measuring Toolkit toward Students’ Cognitive and Procedural Knowledge Achievements
Authors: Adam A S , Lutfiyah A , Mubarok H , Suprapto N 
Published: June 2020

Abstract
Virtual laboratory known as VMT (Virtual Measuring Toolkit) has been developed to succeed in the learning objection in a Junior High School level. This VMT was used in measurement on a natural science subject to involve the active participation in measuring process in an unavailable real laboratory facility. This media contains various measurement tool (caliper, three-arm balance, stopwatch, measuring glass for volume and grid for the area) to use for measuring process with the real using approach. Besides, VMT applies in a complete instruction process, integrate to worksheet and assessment sheet. Furthermore, this particular study aimed to measure the students’ cognitive and procedural knowledge achievement with the support of VMT and describe its attainment level on that knowledge based on certain criteria. The variables measured in an examination setting on 49 students. Besides, the students’ responds to relating media uses are discussed. As a result, the students’ achievement on cognitive and procedural knowledge after the Virtual Measuring Toolkit (VMT) using in learning setting on classroom state in a good with percentage of 69 %. While the students’ positive responds percentage on 85 %.
Parameters (σ, ε) of Lennard-Jones for Fe, Ni, Pb for Potential and Cr based on Melting Point Values Using the Molecular Dynamics Method of the Lammps Program
Authors: Maghfiroh C Y , Arkundato A , Misto  , Maulina W 
Published: June 2020

Abstract
Lennard-Jones potential is the potential energy of the bond interaction between two atoms or free molecules based on the distance between them. Molecular dynamics simulations can be used to calculate various physical properties of materials based on specific interaction potentials. One of the physical properties of a material is its melting point. This research was conducted to find the potential parameter values of Lennard-Jones metal Fe, Pb, Ni and Cr based on the melting point value of the material using the LAMMPS program. In this study the normalization of potential parameters is done by comparing the results of the simulation melting point with the experimental melting point. This research produces a Lennard-Jones potential parameter value which yields a melting point value that has a relatively small description.
Modified Glucose Absorption Equation in An Oral Minimal Model for Type 2 Diabetes Mellitus
Authors: Kartono A , Mufid H M , Wahyudi S T 
Published: June 2020

Abstract
The previously minimal model that has been developed by Bergman is known that blood uptake can be used to the calculations of insulin sensitivity and glucose effectivity in an intravenous glucose tolerance test (IVGTT). In this study, a minimal model Bergman has been modified by adding glucose absorption factors considering the rate of glucose concentration in the small intestine. Based on these present model results, subjects with type 2 diabetes mellitus (T2DM) have higher glucose concentrations and thus require greater insulin performance compared with subject pre-diabetes and normal subject. Besides, subjects with T2DM have lower insulin sensitivity and glucose effectivity compared with subject pre-diabetes and normal subjects. Fitting results obtained from these present model results are obtained using R2 values of glucose and insulin concentration, all values were above 0.90. This shows the validation results of the comparison of all simulation results and experimental data are good.
Project Based Learning Integrated STEM to Increase Students’ Scientific Literacy of Fluid Statics Topic
Authors: Parno  , Yuliati L , Ndadari I P , Ali M 
Published: June 2020

Abstract
Learning in the 21st century deals with literacy skill. In fact, studies investigating Project-Based Learning Integrated Science Technology Engineering and Mathematics (PjBL-STEM) to develop students’ scientific literacy are under-explored. This research investigated the impact of PjBL-STEM on students’ scientific literacy of Fluid Statics topic in three classes, these are, Experiment (PjBL-STEM), Comparison (PjBL), and Control (traditional). In Quasi-Experimental Nonrandomized Control Pretest-Posttest Design environment, students in PjBL-STEM and PjBL classes made three products (Hartl apparatus, miniature of multi-level parking lot, and simple boat). Fluid Statics Scientific Literacy Test with seven discourses and eleven essay items was used with 0.908 Cronbach’s alpha reliability. Data was analysed with one-way ANOVA, post hoc Tukey, N-gain, and Cohen’s effect size. The results showed that three classes had significantly different scientific literacy, where PjBL-STEM was the highest and PjBL class is higher than the traditional class. The literacy improvement of Experiment class included in “high” category and both Comparison and Control classes were in “medium” category. The effect of operational implementation of all pairs of classes belonged in “very large” category in the enhancement of students’ scientific literacy. Students’ response was similar in PjBL-STEM and PjBL classes, though it is higher than traditional class in the final questionnaire.
The Students’ Voice of Volcanology in Education for Sustainable Development Context
Authors: Anggrayni S , Hariyono E , Madlazim  
Published: June 2020

Abstract
The aim of this study is to identify college students’ conception regarding to volcanic phenomena. This study was possessed the conception profile of freshmen in volcanology using questions instrument about volcanology concept and making decision skills instrument test which created by the researchers. A descriptive quantitative approach was used, which included 32 physics students at Surabaya State University as the participants. The result indicated that the physics students have a little understanding about volcanology concept. From all questions provided, they answered correctly less than 50 % only. In line with this, their making decision skills need to be trained. Meanwhile, as science teachers must have a good understanding of this subject matter. Therefore it can be concluded that the evaluated geoscience learning curriculum for pre-service science teachers needs to be evaluated.
Spectroscopic Study on the Film of Polyvinyl Alcohol and Carboxymethyl Cellulose as Polymer Electrolyte Materials
Authors: Putro P A , Yudasari N , Maddu A 
Published: June 2020

Abstract
Polymer electrolytes have emerged as a powerful platform in the progress of more efficient energy storage devices. In this study, polymer electrolyte materials (PEM) was successfully prepared using drop casting method. A spectroscopic study of the film were prepared by variying the ratio of the volume (PVA/CMC) at 100/0, 75/25, 50/50, 25/75 %. The functional groups were investigated using fourier transform infrared (FTIR) spectroscopy. The crystallinity degree obtained by X-ray diffraction (XRD). Their transparency degree were observed by UV-Vis spectroscopy. The ionic conductivity studies obtained by electrochemical impedance spectroscopy (EIS).
Weak Zone Determination Inside The Tunnel Using H/V Ratio Method
Authors: Sanny T A , Naufal H H 
Published: June 2020

Abstract
Tunnel is a vital structure in transportation as it shortens the distance between places through underground. Nevertheless, since it goes via underground, there are several risks might occur, such as tunnel collapse. This occasion will result in plenty of casualties. Therefore, as the preventive attempt, there should be a particular method to determine that the tunnel is strong enough. One of the methods that may work for this case is microtremor and one of the most common method in microtremor is H/V ratio. H/V ratio is able to describe a natural frequency of a place or a structure. By using the natural frequency, the stability of the tunnel can be determined. To test out the method, a measurement is conducted in a tunnel at Institut Teknologi Bandung. This tunnel connects the main campus and the campus sports ground. It also lies under the main road which has a lot of traffics at all time. The measurement is done on the wall side of the tunnel, while the space between measurement station is 6 meters and the station cover the whole tunnel wall side. After measuring the tremor in every station, the tremor data will be processed with Geopsy software and the natural frequency of the tunnel will be acquired. Subsequently, the natural frequency of the entire tunnel will be plotted and the result from this plotting can be used to determine the weak zone of the tunnel.
HYSITS: A MATLAB Code to Process Vibrating Sample Magnetometer Data (Hysteresis Loop)
Authors: Erdyanti R B T , Antareza M A , Tjiongnotoputera K D , Mariyanto M 
Published: June 2020

Abstract
Vibrating-sample magnetometer (VSM) is a magnetic measurement method by observing magnetic moment (M) which is a response of applying ascending and descending magnetic field (H) to the material. The data of this ascending and descending magnetic field will form a kind of loop called hysteresis loop. The hysteresis curve of each material will be different for each kind, so that this curve can be used to evaluate type and domain of magnetic mineral. This paper introduces HYSITS, a MATLAB code for analysing the magnetic hysteresis curve. We aim to provide an easy-use program, such as the feature to adjust smoothing span and increment parameter. With that the hysteresis curve analysis can be done effectively. The optimal result of the parameters adjustment can be seen from the smoothing span 10 for increment values 0,001 and 0,002 on the graph. This MATLAB code will generate 3 plots, which are hysteresis curve (magnetic moment vs. magnetic field), difference of ascending and descending magnetic moment (ΔM vs. H), and the 1st derivative of ΔM vs. H. Although HYSITS has several features that distinguishes it from its non-MATLAB predecessors, HYSITS still needs improvements so that it can be more reliable for research about magnetic hysteresis
The Development of Viscosity Practice Tools Based on Information and Communication Technology Using Arduino and Android on Static Fluid Material for Grade XI Senior High School
Authors: Sandjaja D P , Roza L , Hidayat M N , Rosyid F A , Makdiani N 
Published: June 2020

Abstract
A difficult practicum activity has become a problem with students’ activities and lack of use on ICT-based practice tools, especially Android. The purpose of this research is to develop physics learning media in the form of practical tools and Android applications on static fluid material with a focus on viscosity. This research is development research by adopting the Borg & Gall development model. At the initial research and information gathering stage, the problem and needs analysis activities are carried out. In the planning stage, an initial design is carried out. During the initial product format development phase, the prototype is designed as a manifestation of the defined ideas and ideas. In the initial trial phase, the media are tested on material experts and media experts and then evaluated. At the field trial stage, the media were tested on a small scale with 30 respondents. Data obtained through the observation method were analyzed descriptively qualitatively. While the validation data were analyzed descriptively qualitative and quantitative. The average score of material expertise was 79.78% (good), media expertise was 82.59% (good), small scale test was 84.78% (good). So it can be concluded that this application is suitable for use as a medium for learning physics.