bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cohort profile for the STratifying Resilience and Depression Longitudinally (STRADL) study: A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments
Authors: Habota Tina , Sandu Anca-Larisa , Waiter Gordon D. , McNeil Christopher J. , Steele J. Douglas , Macfarlane Jennifer A. , Whalley Heather C. , Valentine Ruth , Younie Dawn , Crouch Nichola , Hawkins Emma L. , Hirose Yoriko , Romaniuk Liana , Milburn Keith , Buchan Gordon , Coupar Tessa , Stirling Mairi , Jagpal Baljit , MacLennan Beverly , Priba Lucasz , Harris Mathew A. , Hafferty Jonathan D. , Adams Mark J. , Campbell Archie I. , MacIntyre Donald J. , Pattie Alison , Murphy Lee , Reynolds Rebecca M. , Elliot Rebecca , Penton-Voak Ian S. , Munafò Marcus R. , Evans Kathryn L. , Seckl Jonathan R. , Wardlaw Joanna M. , Lawrie Stephen M. , Haley Christopher S. , Porteous David J. , Deary Ian J. , Murray Alison D. , McIntosh Andrew M. 
Published: November 2019

STratifying Resilience and Depression Longitudinally (STRADL) is a population-based study built on the Generation Scotland: Scottish Family Health Study (GS:SFHS) resource. The aim of STRADL is to subtype major depressive disorder (MDD) on the basis of its aetiology, using detailed clinical, cognitive, and brain imaging assessments. The GS:SFHS provides an important opportunity to study complex gene-environment interactions, incorporating linkage to existing datasets and inclusion of early-life variables for two longitudinal birth cohorts. Specifically, data collection in STRADL included: socio-economic and lifestyle variables; physical measures; questionnaire data that assesses resilience, early-life adversity, personality, psychological health, and lifetime history of mood disorder; laboratory samples; cognitive tests; and brain magnetic resonance imaging. Some of the questionnaire and cognitive data were first assessed at the GS:SFHS baseline assessment between 2006-2011, thus providing longitudinal measures of depression and resilience. Similarly, routine NHS data and early-life variables are linked to STRADL data, further providing opportunities for longitudinal analysis. Recruitment has been completed and we consented and tested 1,188 participants.
MENGENAL KEPITING Ashtoret lunaris (FORSKAL, 1775) DARI SUKU MATUTIDAE (CRUSTACEA: DECAPODA: BRACHYURA)
Authors: Widyastuti Ernawati 
Published: November 2019

KNOWING Ashtoret lunaris (FORSKAL, 1775) FROM MATUTIDAE (CRUSTACEA: DECAPODA: BRACHYURA). Ashtoret lunaris is a species of genus Ashtoret from Matutidae. This crab is known as “yellow moon crab”, because it has a yellow and rounded carapace like a full moon. These crabs are nocturnal and live in coastal areas with soft substrate. The crab has a wide distribution spanning from the Red Sea to South Africa, Asia and Australia. Some biological aspects such as morphology, systematic, habitat, feeding habit, distribution and others are discussed in this paper.
EKSISTENSI DAN KERAGAAN IKAN DI DAERAH ALIRAN SUNGAI CIBANTEN
Authors: Saputra Ishaaq , Muklasin Muklasin , Indaryanto Forcep Rio , Rahardjo Sinung 
Published: November 2019

Sungai Cibanten merupakan salah satu sungai yang memiliki peranan penting di Provinsi Banten. Sungai ini memiliki hulu yang berlokasi di Situ Cibanten, Ciomas, Kabupaten Serang. Tujuan dari penelitian ini adalah untuk mengevaluasi keberadaan, keanekaragaman dan keseragaman ikan di Sungai Cibanten. Pada penelitian ini, diperoleh ikan sebanyak 135 ekor ikan. Berdasarkan hasil identifikasi spesies yang dilakukan, ikan – ikan tersebut berasal dari lima family ikan yaitu Cyprinidae, Loricariidae, Palaemonidae, Zenarchopteridae dan Penaeidae. Selain itu, diperoleh sejumlah tujuh spesies ikan termasuk satu ikan asing yaitu ikan sapu-sapu (Pterygoplichthys pardalis). Hasil analisa menunjukkan bahwa indek keanekaragaman, keseragaman dan dominasi pada seluruh titik sampling masih dalam kondisi normal. Namun demikian, dengan ditemukannya ikan sapu-sapu (P. pardalis) pada sistem Sungai Cibanten mungkin akan memiliki dampak negatif terhadap ekologi sungai. Penelitian lebih lanjut dibutuhkan untuk mengevaluasi lebih lanjut keberadaan ikan sapu-sapu dan ikan asing lainnya yang memiliki potensi bahaya terhadap ekologi Sungai Cibanten.
Quality indicators for hip and knee osteoarthritis management in New Zealand: A patient survey
Authors: Larmer Peter J. , Bennett Katie , Baldwin Jennifer N. , Bassett Sandra , O’Brien Daniel W. 
Published: November 2019

Osteoarthritis is a prevalent and costly condition. Knowledge of the quality of care being offered to people with hip and knee osteoarthritis in New Zealand is limited. The aim of this study was to investigate the quality of care being offered to people with hip and knee osteoarthritis in New Zealand, and to investigate common pathways of care. The OsteoArthritis Quality Indicator (osteoarthritis) questionnaire was administered to adults with hip and/or knee osteoarthritis, and participants were also asked to list the healthcare professionals they had consulted. Descriptive statistics with 95% confidence intervals were calculated. The study included 106 participants (87% female, n = 92; 94% European, n = 100). The mean OsteoArthritis Quality Indicator achievement rate was 50.2% (95% confidence intervals 41.0–59.7%). OsteoArthritis Quality Indicator achievement rates were lowest for weight reduction referral (8.6%; 3.7–17.8%) and daily activity aids assessment (18.5%; 10.2–31.0%), and highest for physical activity education (80.8%; 72.1–87.3%) and offering of paracetamol (80.0%; 71.3–86.6%). Following consultation with a general practitioner, 22% (n = 24) consulted orthopaedic surgeons while 15% (n = 17) consulted physiotherapists. The results suggest that implementation of evidence informed conservative treatments for osteoarthritis in primary care is suboptimal, although evidence from a larger representative sample is needed.
Exploratory dimensions of the attitude toward occupational health
Authors: García Lirios Cruz 
Published: November 2019

In the context of health policies, the psychological processes of identity and stigma are a team that tries to explain assessment processes lifestyles related to vulnerable groups. Indeed, the aim of this study is to establish the validity and reliability of an instrument that measured four dimensions on a scale of attitudes. A cross - sectional and correlational study was conducted to establish the psychometric properties of the instrument with a non - probabilistic intentional sample of 258 students from a public university. The results show both dimensions as preponderant factors of attitude, but their inclusion in the construct was taken as part of a process of spontaneous activation; actions and risks that only carriers close to group can perform.RESUMENEn el contexto de las políticas de salud, los procesos psicológicos de identidad y estigma son un conjunto que trata de explicar los procesos de evaluación de los estilos de vida relacionados con los grupos vulnerables. De hecho, el objetivo de este estudio es establecer la validez y confiabilidad de un instrumento que mide cuatro dimensiones en una escala de actitudes. Se realizó un estudio transversal y correlacional para establecer las propiedades psicométricas del instrumento con una muestra intencional no probabilística de 258 estudiantes de una universidad pública. Los resultados muestran ambas dimensiones como factores preponderantes de la actitud, pero su inclusión en el constructo se tomó como parte de un proceso de activación espontánea; Acciones y riesgos que solo las operadoras cercanas al grupo pueden realizar.RESUMONo contexto das políticas de saúde, os processos psicológicos de identidade e estigma são uma equipe que tenta explicar os processos de avaliação de estilos de vida relacionados aos grupos vulneráveis. De fato, o objetivo deste estudo é estabelecer a validade e a confiabilidade de um instrumento que mede quatro dimensões em uma escala de atitudes. Foi realizado um estudo transversal e correlacional para estabelecer as propriedades psicométricas do instrumento com uma amostra intencional não probabilística de 258 estudantes de uma universidade pública. Os resultados mostram ambas as dimensões como fatores preponderantes de atitude, mas sua inclusão no construto foi tomada como parte de um processo de ativação espontânea; ações e riscos que somente as operadoras próximas ao grupo podem executar.
Effective Self-Efficacy Factors in Empowerment of Health Care Networks Managers in East Azerbaijan, West Azerbaijan and Ardebil Provinces, Iran
Authors: Yousef Yaghoobi Fatemeh , Riahi Leila , Tabibi Seyed Jamaleddin , Majdabadi Farahani Mahmood Mahmoodi 
Published: November 2019

Introduction: Empowerment has determinant role in developing the ability of individuals in order to achieve sustainable improvement in efficiency of the health care organizations. This study was carried out to identify the variables and effective self-efficacy components affecting the manager’s empowerment in Health­ Care Networks during 2018-19.
Methods: This is an applied and exploratory study. At first, the variables involving in the empowerment of human resources were extracted by reviewing the literature as well as interviewing with the specialists. Then, the conceptual model was designed, the questionnaire compiled and its validity and reliability confirmed. The data were collected through the completing of the questionnaire by 416 managers who were chosen via stratified random sampling method and analyzed using exploratory and confirmatory factor analysis.
Results: According to the results of the exploratory factor analysis, the variable “continuous training” with the factor loading of 0.84 was found the most important variable. Concerning the standard coefficients of confirmatory factor analysis, variables of all the three components of self-efficacy were significant (p<0.001) and the component “Believe in responsibly ability and skill in work” (factor loading = 0.96) had the higher effect on self-efficacy. The impact rate of self-efficacy in empowerment with 0.96 and the variables “having job skills” and "emotional arousal" with 0.79 factor loading are considered as the most significant variables.
Conclusion: The Universities of Medical Sciences and Health Care Networks can improve the ability of the managers through continuous training, promotion of professional skills, responsibility and presenting the successful models and experiences.
The role of TNF-alpha gene (-238G/A and -308G/A) polymorphisms in the etiology and pathogenesis of inflammatory bowel diseases in various ethnic groups
Authors: Zhilin I. V. , Chashkova E. Yu. , Zhilina A. A. , Pushkarev B. S. , Korotaeva N. S. 
Published: November 2019

This literature review deals with specifics of the natural course of inflammatory bowel disease (IBD) in patients from various ethnic groups and -308G/A and -238G/A promoter polymorphisms in tumor necrosis factor-alpha (TNF-α) gene. The search in PubMed, Medline, Еlibrary.ru databases has led to identify in total 20 studies, including 2 meta-analyses, on the role of TNF-α-308G/A and -238G/A gene polymorphism in the etiology and pathophysiology of IBD. The TNF-α-308G/A polymorphism is associated with increased secretion of this proinflammatory cytokine, whereas the TNF-α-238G/A genotype is characterized by reduced TNF-α secretion. A number of studies have shown an association between TNF-α-308G/A gene polymorphism and severe course of IBD, requiring more active treatment of patients (cytostatics, corticosteroids, biological agents). Some investigators have found that the patients carriers of TNF-α-308G/A had a higher probability of surgical interventions. The association between TNF-α-308G/A and the phenotypic characteristics of IBD has been identified in studies performed in Europe, Asia, and Russia. The association of this polymorphism with the prevalence of ulcerative colitis has been proven in some studies, in particular, in the Asian population. Similar associations have been noted in few publications originating from Europe and North America, while some studies have found no links between TNF-α-308G/A, -238G/A, and the course of IBD. TNF-α-238G/A gene polymorphism has not shown any significance for the prevalence and course of ulcerative colitis and Crohn's disease. One can assume that the differences in the study results arising from one and the same geographical area are related to genetic heterogeneity of the study groups, phenotypic variances between the study subjects, as well as relatively small sample sizes. Currently, the search for genetic, biochemical and other prognostic criteria for IBD course is in progress. There are studies in progress to investigate the mechanisms of transformation of the genetic information into the particulars of ulcerative colitis and Crohn's disease manifestations, with consideration of ethnicity.
Individual and community level predictors of maternal timely postnatal care services utilization in Ethiopia: A multilevel-mixed effects analysis
Authors: Tadele Afework , Getinet Masrie 
Published: November 2019

Abstract
Introduction: Early identification and management of postpartum complications through timely visit for postnatal care is one of the key interventions in reducing maternal mortality. A community-based national level representative dataset was necessary to inform decision makers in achieving the sustainable development goal (SDG) target of reducing maternal mortality by 70%. This study aims to determine the individual and community level predictors of timely utilization of maternal postnatal care service in Ethiopia. Methods: A community based nationally representative survey of Ethiopian Demographic and Health Survey (EDHS) in 2016 was utilized. A total of 3,948 women aged 15-49 giving birth in the two years before the survey were included. A two-level mixed-effects logistic regression analysis was employed. Result: Among women aged 15-49 years giving birth in the 2 years before the survey, 17% had a postnatal check during the first 2 days after birth in Ethiopia. Institutional delivery AOR 2.14 [95% C.I 1.70, 2.0] and giving birth by caesarean section AOR 1.66 [95% CI 1.10, 2.50] were found to be an individual level determinants, whereas administrative regions(Oromia 69%, Somali 56%, Benishangul 55%, SNNPR 43%, Gambela 66%, Afar 50% and Dire Dawa 55% which less likely to utilize postnatal care utilization as compared to Addis Ababa city administrative area), Higher community level wealth AOR 1.44 [95% C.I 1.08, 1.2], antenatal care coverage AOR 1.52 [95% C.I 1.19, 1.96] and perceived distance of the health facility as a big problem AOR 0.78[95% C.I 0.60, 0.99] were the community level predictors of timely utilization of post-natal care in Ethiopia. Conclusion: Less than one in five women utilized postnatal care in the first 2 days after birth in Ethiopia. Individual level factors (being gave birth at health facility and caesarean delivery) and community level factors (administrative regions, community level wealth, antenatal care and perception of distance to health facility as a big problem) were found to be significant predictors. Keywords: Postnatal care; multilevel; DHS; Ethiopia
An efficient method for immortalization of amniocytes with chromosome abnormalities for renewable application of rare disease sources
Authors: Weng Binghuan , Shen Xiao-yun , Chen Na , Yu Xiao-peng , Xu Wei , Yang Hao-kun 
Published: November 2019

Abstract
Objective: We describe a new method of immortalizing amniocytes with chromosome abnormalities to generate renewable resources for studying rare diseases. Methods: Three methods were investigated by randomly dividing 180 cases of adherent amniocytes into groups A, B, and C. Group A cells were digested with 0.25% trypsin for 10, 20, 30, 60, 90, and 120 mins. Group B and C cells were digested with 0.25% trypsin for 3–5 minutes. Group A and B cells were then transfected with PT67 cell-produced SV40LT. Group C digested cells underwent liposome-mediated SV40LT-transfection. Results: The percentage of clones immortalized by SV40LT transfection in groups A, B, and C were 18.3, 5.0, and 16.7%, respectively, after G418 screening. Group A produced a higher percentage of immortalized clones than did groups B and C, but only significantly differed from group B. The karyotypes and chromosome 13, 18, 21, X, and Y fluorescence signals in transfected cells of all groups were identical to those of the primary cells after passaging for 10–15 generations. Conclusions: The trypsin-mediated SV40LT transfection used in group A can be applied for routine establishment of amniocyte lines to obtain a renewable resource for the study of rare diseases and as quality control materials for prenatal diagnosis.
Phytoremediation of nitrate contaminated water using ornamental plants
Authors: Shyamala S. , Manikandan N. Arul , Pakshirajan Kannan , Tang Van Tai , Rene Eldon R. , Park Hung-Suck , Behera Shishir Kumar 
Published: November 2019

Abstract
This work aims at evaluating the potential of two ornamental plant species, i.e., money plant (Epiprennum aureum) and arrowhead plant (Syngonium podophyllum), to treat nitrate containing wastewater. Statistically designed experiments were performed to ascertain the effect of initial nitrate concentration (40–120 mg/L), growth period (1–12 days) and plant density (20–80 g/L) on nitrate removal. Based on the results of analysis of variance (ANOVA), it was observed that the individual effects (F = 78.04 and P = 0.013) of process parameters influenced the nitrate removal efficiency by money plant stronger than the 2-way (F = 0.2 and P = 0.89) and 3-way interaction effects (F = 0.46 and P = 0.569). In the case of the arrowhead plant, the individual effects significantly affected the nitrate removal efficiency than the 2-way and 3-way interaction effects. Low nitrate concentrations (40 mg/L) and high plant density (80 g/L), showed ∼88% nitrate removal by arrowhead plant, during a growth period of 6 d. On the contrary, under similar conditions, the money plant showed a nitrate removal efficiency of ∼93% during a growth period of 12 d. Concerning the removal kinetics, an increase in the growth period increased the nitrate removal rate for both the plants.
A emergência de domínio funcional e a abordagem construcional da gramática
Authors: Aguiar Vieira Caio , Viana Sousa Valéria 
Published: November 2019

Partindo da concepção de língua adotada pela Gramática de Construções (CROFT, 2001) e da perspectiva construcional da mudança (TRAUGOTT; TROUSDALE, 2013; TEIXEIRA; ROSÁRIO, 2016), objetivamos, neste estudo, analisar o deslizamento de domínio funcional do que nem na Língua Portuguesa. Para tanto, ancoramo-nos nos estudos de Vieira e Sousa (2019), que se debruçaram na investigação do que nem como conector e na análise construcional empreendida por Sambrana (2017) a respeito dos Marcadores Discursivos (MDs). Como recurso metodológico, utilizamos os dados de fala dos Corpora Popular e Culto de Vitória da Conquista, além de empregarmos o método qualitativo para a análise dos dados. Os resultados mostraram que o que nem está em processo de deslocamento de domínio funcional e passa a integrar, também, a rede construcional dos MDs, na rota [QUE NEM]conect --> [QUE NEM]md, sendo utilizado, sobretudo, com a função de manutenção do turno conversacional.
TRADISI MITOS SANGKAL DALAM PERTUNANGAN DINI PERSPEKTIF KIAI DI MADURA
Authors: Kuswandi Iwan , Azizah Lilik Fadilatin 
Published: November 2019

This paper aims to analyze early childhood engagement in Pragaan, Madura. In this case, the focus of his study is on the views of the kiai in the area regarding people's belief in the myth of sangkal tako’ in the tradition of early engagement. This research uses a qualitative approach, with a type of case study. The location of this study is in Pragaan District, Sumenep Regency, Madura. The results of this study indicate that the kiai in Pruruan District, agree on the tradition of early engagement in their area, not in conflict with Islamic law. However, some scholars think that the blessing of parents is a condition of engagement, and some others say that girls are free to choose a partner. Furthermore, the myth of sangkal in the tradition of early childhood engagement is considered not to violate the Islamic Shari'a and is considered a habit (al'adah).
Effect of Diode Laser on Gingival Crevicular Fluid Stromal Derived Factor – 1 Alpha Level in Chronic Periodontitis Patients- A Randomized Clinical Trial
Authors: M.P. Rakesh , Kripal Krishna , R. Deepthi , Prabhu Sandeep S. , P.A. Shanmugapriya 
Published: November 2019

Background: SDF-1α may be involved in the immune defense pathway activated during periodontal disease. Upon development of disease, SDF-1α levels increase and may recruit host defensive cells into sites of inflammation. This suggests that SDF-1α may be a useful biomarker for the identification of periodontal disease progression. Previous studies suggested that diode laser using as an adjunct to SRP in clinical and biochemical benefits.
Aims and objectives: The aim of the present study was to assess the effect of diode laser on gingival crevicular fluid stromal derived factor – 1 alpha (SDF-1α) level in chronic generalized periodontitis patients.
Materials and methods: A total of 30 patients were divided in two groups based on inclusion and exclusion criteria as follows: Group 1: 15 chronic generalized periodontitis patients who received treatment with scaling and root planing. Group 2: 15 chronic generalized periodontitis patients who received treatment with scaling and root planing and diode laser. Each GCF samples were collected at baseline, 15 days and 21 days after treatment. Clinical parameters like gingival index, probing pocket depth and clinical attachment level were recorded and GCF samples also collected.
Results: All the clinical parameters (GI, PPD, CAL) and the concentration of SDF-1α level in GCF were found to be significantly reduced in the group 2 compared to group 1 after 21 days. The mean values of GI, PPD, CAL parameters at different time intervals was found statistically significant in both the groups (p<0.001).
Conclusion: Within the limitations of the present study, we conclude that diode laser used as an adjunct to SRP provides greater improvement in clinical and biochemical benefits over conventional mechanical treatment during medium term of observation.
Echocardiographic outcomes from seven randomized trials of transcatheter versus surgical aortic valve replacement
Authors: Takagi Hisato , Hari Yosuke , Nakashima Kouki , Kuno Toshiki , Ando Tomo 
Published: November 2019

Aims
We performed meta-analyses of echocardiographic outcomes, including postprocedural aortic valve area (AVA), aortic valve mean pressure gradient (MPG), and paravalvular aortic regurgitation (PAR), exclusively from all currently available randomized controlled trials (RCTs) of transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR).

Methods
To identify all RCTs providing echocardiographic outcomes (AVA, MPG, and PAR) up to 2 years after TAVI versus SAVR, PubMed and ClinicalTrials.gov were searched through June 2019. Mean differences in AVA (and MPG) between the TAVI and SAVR groups and odds (or hazard) ratios of at least moderate PAR for TAVI versus SAVR were pooled using the random-effects meta-analysis.

Results
We identified seven eligible RCTs. At 30 days (P = 0.004), 1 year (P = 0.006), and 2 years (P = 0.03), AVA was significantly larger after TAVI than after SAVR. After TAVI than after SAVR, MPG was significantly lower at 30 days (P = 0.03) and 2 years (P = 0.01), and nonsignificantly lower at 1 year (P = 0.06). At 30 days (P < 0.00001), 1 year (P < 0.00001), and 2 years (P < 0.00001), incidence of at least moderate PAR was significantly greater after TAVI than after SAVR.

Conclusion
On the basis of the present meta-analyses of all the seven currently available RCTs, AVA is larger, MPG is lower, and incidence of at least moderate PAR is greater 30 days, 1 and 2 years after TAVI than after SAVR.