bluuebunny/crossref_metadata_2025_split huggingface dataset:
Real-time Inference and Detection of Disruptive EEG Networks for Epileptic Seizures
Authors: Bomela Walter , Wang Shuo , Chou Chun-An , Li Jr-Shin 
Published: May 2020

AbstractRecent studies in brain science and neurological medicine paid a particular attention to develop machine learning-based techniques for the detection and prediction of epileptic seizures with electroencephalogram (EEG). As a noninvasive monitoring method to record brain electrical activities, EEG has been widely used for capturing the underlying dynamics of disruptive neuronal responses across the brain in real-time to provide clinical guidance in support of epileptic seizure treatments in practice. In this study, we introduce a novel dynamic learning method that first infers a time-varying network constituted by multivariate EEG signals, which represents the overall dynamics of the brain network, and subsequently quantifies its topological property using graph theory. We demonstrate the efficacy of our learning method to detect relatively strong synchronization (characterized by the algebraic connectivity metric) caused by abnormal neuronal firing during a seizure onset. The computational results for a realistic scalp EEG database show a detection rate of 93.6% and a false positive rate of 0.16 per hour (FP/h); furthermore, our method observes potential pre-seizure phenomena in some cases.
Substantia nigra echogenicity is associated with serum ferritin, gender and iron-related genes in Parkinson’s disease
Authors: Li Kai , Ge Yi-Lun , Gu Chen-Chen , Zhang Jin-Ru , Jin Hong , Li Jiao , Cheng Xiao-Yu , Yang Ya-Ping , Wang Fen , Zhang Ying-Chun , Chen Jing , Mao Cheng-Jie , Liu Chun-Feng 
Published: May 2020

AbstractSubstantia nigra (SN) hyperechogenicity is present in most Parkinson’s disease (PD) cases but is occasionally absent in some. To date, age, gender, disease severity, and other factors have been reported to be associated with SN hyperechogenicity in PD. Previous studies have discovered that excess iron deposition in the SN underlies its hyperechogenicity in PD, which may also indicate the involvement of genes associated with iron metabolism in hyperechogenicity. The objective of our study is to explore the potential associations between variants in iron metabolism-associated genes and SN echogenicity in Han Chinese PD. Demographic profiles, clinical data, SN echogenicity and genotypes were obtained from 221 Han Chinese PD individuals with a sufficient bone window. Serum ferritin levels were quantified in 92 of these individuals by immunochemical assay. We then compared factors between PD individuals with SN hyperechogenicity and those with SN hypoechogenicity to identify factors that predispose to SN hyperechogenicity. Of our 221 participants, 122 (55.2%) displayed SN hyperechogenicity, and 99 (44.8%) displayed SN hypoechogenicity. Gender and serum ferritin levels were found to be associated with SN hyperechogenicity. In total, 14 genes were included in the sequencing part. After data processing, 34 common single nucleotide polymorphisms were included in our further analyses. In our data, we also found a significantly higher frequency of PANK2 rs3737084 (genotype: OR = 2.07, P = 0.013; allele: OR = 2.51, P = 0.002) in the SN hyperechogenic group and a higher frequency of PLA2G6 rs731821 (genotype: OR = 0.45, P = 0.016; allele: OR = 0.44, P = 0.011) in the SN hypoechogenic group. However, neither of the two variants was found to be correlated with serum ferritin. This study demonstrated that genetic factors, serum ferritin level, and gender may explain the interindividual variability in SN echogenicity in PD. This is an explorative study, and further replication is warranted in larger samples and different populations.
Isokinetic Performance of Shoulder External and Internal Rotators of Professional Volleyball Athletes by Different Positions
Authors: Kim Do-Kyung , Park Geon , Kuo Liang-Tseng , Park Won-Hah 
Published: May 2020

AbstractThis study aimed to exam the isokinetic shoulder rotator strength of professional volleyball athletes, by playing positions. This cross-sectional study included a total of 49 healthy male professional volleyball players. We measured the isokinetic strength of the external rotator (ER) and internal rotator (IR) muscles and compared the dominant and non-dominant shoulders at angular speeds of 60°/s and 180°/s. In ER, all positions of players had similar strength between the dominant shoulder and non-dominant shoulders. Conversely, all playing positions except libero had stronger strength in dominant shoulder than that in the non-dominant shoulder. The ER/IR ratio in the dominant shoulder was significantly lower only for the attacker (outside hitter and opposite) at 60°/s and 180°/s (P < 0.0001; P = 0.0028 respectively) and blocker at 60°/s (P = 0.0273) when compared with non-dominant shoulder. Furthermore, the attacker had a lower ER/IR ratio in the dominant shoulder than setter and libero at 60°/s and 180°/s. For elite volleyball players without injury, the dominant shoulder had a higher strength of internal rotation, causing the relative muscle imbalance than the non-dominant shoulder, especially for the attacker and blocker positions. Training program should be individualized for each playing position to improve the imbalanced shoulder.
Multi-messengers at ultra-high energies with the Pierre Auger Observatory
Authors: Souchard Julien 
Published: May 2020

The Pierre Auger Observatory is an Ultra-High Energy Cosmic Ray (UHECR) detector which has studied cosmic particles with energies above and around 1018 eV for more than 15 years. It has proved to be the most competitive instrument at these energies and has produced a wealth of valuable results, improving our understanding of UHECRs. A complete understanding of these highest energy particles is crucial to understand the extreme astrophysical events in which they are produced and accelerated, as well as their propagation to Earth. In the same range of energies, UHE photons and neutrinos are of paramount importance as, being electrically neutral, they point back to their origin while charged particles are deflected in the galactic and extragalactic magnetic fields. The flux of extragalactic photons, neutrinos, and cosmic rays are believed to be highly linked, by their origin and their interactions. Each messenger provides different information about the potential sources, and having detection means for all four messengers, including gravitational waves, allows us to shed light on energetic sources of astroparticles. The Pierre Auger Observatory benefits from a large exposure and a good angular resolution, and is efficient in detecting UHE photons and neutrinos. These performances make possible follow-up searches for events detected by gravitational waves, such as the binary mergers observed by the LIGO/Virgo detectors, or any other energetic sources of particles.
A Clinical Method for Estimation of VO2max Using Seismocardiography
Authors: Sørensen Kasper , Poulsen Mathias Krogh , Karbing Dan Stieper , Søgaard Peter , Struijk Johannes Jan , Schmidt Samuel Emil 
Published: May 2020

AbstractThe purpose of this study was to investigate the correlation between the seismocardiogram and cardiorespiratory fitness. Cardiorespiratory fitness can be estimated as VO2max using non-exercise algorithms, but the results can be inaccurate. Healthy subjects were recruited for this study. Seismocardiogram and electrocardiogram were recorded at rest. VO2max was measured during a maximal effort cycle ergometer test. Amplitudes and timing intervals were extracted from the seismocardiogram and used in combination with demographic data in a non-exercise prediction model for VO2max. 26 subjects were included, 17 females. Mean age: 38.3±9.1 years. The amplitude following the aortic valve closure derived from the seismocardiogram had a significant correlation of 0.80 (p<0.001) to VO2max. This feature combined with age, sex and BMI in the prediction model, yields a correlation to VO2max of 0.90 (p<0.001, 95% CI: 0.83–0.94) and a standard error of the estimate of 3.21 mL·kg−1·min−1 . The seismocardiogram carries information about the cardiorespiratory fitness. When comparing to other non-exercise models the proposed model performs better, even after cross validation. The model is limited when tracking changes in VO2max. The method could be used in the clinic for a more accurate estimation of VO2max compared to current non-exercise methods.
Recommendations of the Thoracic Imaging Section of the German Radiological Society for clinical application of chest imaging and structured CT reporting in the COVID-19 pandemic
Authors: Vogel-Claussen Jens , Ley-Zaporozhan Julia , Agarwal Prerana , Biederer Jürgen , Kauczor Hans-Ulrich , Ley Sebastian , Kühl Hilmar , Mueller-Lisse Ullrich G. , Persigehl Thorsten , Schlett Christopher L. , Wormanns Dag , Antoch Gerald , Hamer Okka W. 
Published: May 2020

This information provided by the Thoracic Imaging Section of the German Radiological Society is intended to give physicians recommendations on the use of thoracic imaging procedures in the context of the current COVID-19 pandemic. It represents the consensus of the authors based on the previous scientific knowledge and is intended to provide guidance for unified, structured CT reporting if COVID-19 pneumonia is suspected. The recommendations presented correspond to state of knowledge at the time of print and will be updated according to the results of ongoing and future scientific studies.
Key Points:

Citation Format
Triple renal arteries and retro aortic left renal vein -a case report
Authors: Parimala N. B.S. , Prabha Ch. Ratna , Rao M. Prabhakara 
Published: May 2020

AbstractThe renal arteries take origin from the lateral aspect of aorta little below the origin of superior mesenteric artery at the level of L2 vertebra. During routine dissection of an elderly female cadaver aged 60 years triple renal arteries & retro aortic left renal vein was found. The comprehensive knowledge of the renal arterial pattern which remains as the key issue in determining the technical feasibility of surgical interventions as well as the post operative management.
Redo Transanal Soave Pull Through with or without Assistance in Hirschsprung Disease: An Experience in 46 Patients
Authors: Peng Chunhui , Chen Yajun , Pang Wenbo , Zhang Tingchong , Wang Zengmeng , Wu Dongyang , Wang Kai 
Published: May 2020

Abstract
Introduction Transanal Soave pull through (PT) with or without assistance can be performed as a redo procedure for Hirschsprung disease (HD). In this study, we reviewed the indications and clinical outcomes of redo transanal Soave with or without assistance.
Materials and Methods A retrospective analysis was performed on patients who underwent redo transanal Soave with or without assistance in our hospital from 2004 to 2016, and did not have rectourethral fistula or rectovaginal fistula. The Krickenbeck classification system was used to evaluate postoperative bowel function. We analyzed the associated factors of the two main indications.
Results In this study, 46 patients were included, representing 5.6% of all HD PTs; 42 patients were initially operated elsewhere and 4 at our hospital. Primary PT surgeries included 38 transanal Soave, 2 Rehbein, 1 Martin, and 5 unknown procedures. The indications for redo PT were residual aganglionosis/transition zone PT (RA/TZPT) (27, 58.7%), anastomotic complication (14, 30.4%), and dilated distal segment (5, 10.9%). The median age of these 46 patients at primary and redo PT was 7.0 months (range, 0.4–137 months) and 45.5 months (range, 7–172 months), respectively. All 46 patients underwent redo transanal Soave PT; 43 patients (93.5%) underwent transanal Soave with laparotomy (n = 42) or laparoscopy (n = 1), and another 3 patients underwent transanal Soave PT. Six patients (13%) experienced complications within 30 days after redo surgery. A total of 43 patients were followed up, and the median follow-up period was 100 months (range, 35–180 months). Two patients could not hold back defecation in some inconvenient conditions. Sixteen patients (37.2%) had soiling, and 8 (18.6%) of 16 patients complained frequent soiling occurrence (more than 1/week). Only one patient complained of constipation (grade 1). Patients with anastomotic complication had more early postoperative complication and higher rate of soiling than patients with RA/TZPT, but there was no statistical difference (p = 0.672 and p = 0.105).
Conclusion Transanal Soave PT with or without assistance was effective in resolving different problems after initial PT, while soiling was the most common postoperative problem, especially patients with anastomotic complication.
A Rare Case of Heterotopic Ossification of the Patella Tendon in an Adolescent Presenting with Tendon Rupture
Authors: Supreeth Sam , Al-Barwani Aliya , Al Habsi Ismail , Al Ghanami Suwailim , Al Abri Zahra , Al-Adawi Khadija 
Published: May 2020

AbstractHeterotopic ossification is the abnormal formation of mature, lamellar bone in nonosseous tissue such as tendons, ligaments, muscles, and soft tissue. We discuss a rare case of a young adolescent with patellar tendon rupture postheterotopic ossification. A 13-year-old male presented to us with knee pain and inability to extend for 6 weeks following trivial trauma. Preliminary radiological investigations revealed a high riding patella with ossification in the patella tendon. The magnetic resonance scan confirmed the same with patellar tendon disruption and heterogeneous ossification. He underwent surgery with patella tendon repair, augmentation with autograft, and had complete recovery at 6 months' follow-up.
Utility of Rapid Exome Sequencing in the Diagnosis of a Rare Congenital Myasthenic Syndromes in a Preterm Infant
Authors: Bhattacharjee Indrani , Friedman Neil , Rodriguez Ricardio J. 
Published: May 2020

AbstractCongenital myasthenic syndromes (CMS) are rare and challenging diagnoses in preterm neonates. We presented in this case report a preterm infant with recurrent extubation failures. An exhaustive workup to rule out common etiologies of chronic ventilator dependence was negative including a neostigmine trial, acetylcholine receptor antibodies, and chromosomal microarray. Electromyography (EMG) showed features of a neuromuscular junction defect. After ruling out metabolic, inflammatory, and immune mediated causes, a rapid exome sequencing demonstrated CHRNB1 gene mutation diagnostic of autosomal dominant slow channel CMS. The patient was started on fluoxetine and nebulized salbutamol with a gradual improvement in her respiratory function over time with minimal ventilator support.
Poe, insanity, and containing the feminine monstrous
Authors: Hayes Tracy 
Published: May 2020

AbstractIn fiction, unlike his life, Poe was able to contain his women. He derived many features from the European Gothic tradition, and utilized motifs such as incarceration, premature burial, and the pathetic fallacy, or the use of external landscape to express or reflect psychological turmoil. Poe’s psychologically intense tales feature narrators whose mental fabric disintegrates before the reader’s eyes. This essay will concentrate upon three such tales: ‘Berenice’ (1835), ‘Ligeia’ (1838), and ‘The Fall of the House of Usher’ (1839). Each of these stories are narratives of obsession and monomania featuring female incarceration and objectification, and the threat of the feminine monstrous. Berenice, Ligiea and Madeline Usher each embody the feminine monstrous in varying ways, a masculine projection of womanhood unrestrained, unsuccessfully repressed by their male counterparts, and thus returning in an act of unheimliche consummation. Berenice symbolizes the vagina dentata whose threat must be removed through dental extraction; Ligeia is an incubus who perverts the Eucharist in order to achieve an act of monstrous metempsychosis; and Madeline acts as both monstrare and monere: as both the warning and the source of impending destruction. The perceived female abandonment and thus betrayal which had become a pattern of Poe’s life was through his fiction able to be halted and contained. The inextricable link between Eros and Thanatos undergirds these stories in which, in a mirror of Poe’s own life, each love object wastes away during the prime of her beauty. This essay discusses the context of male–female relations in Poe’s life and how they impact upon his fiction. Unlike reality, in his tales Poe was able to resurrect the objects of his obsessions, and thus the female figures comprising the monstrous loves of his male protagonists. However, this essay also questions the extent to which such resurrections and containment are successful within each narrative, and how far Poe’s delineations of the feminine monstrous and unheimlich sexuality can be read as interrogations of compromised masculinity.
Past and future decline of tropical pelagic biodiversity
Authors: Yasuhara Moriaki , Wei Chih-Lin , Kucera Michal , Costello Mark J. , Tittensor Derek P. , Kiessling Wolfgang , Bonebrake Timothy C. , Tabor Clay R. , Feng Ran , Baselga Andrés , Kretschmer Kerstin , Kusumoto Buntarou , Kubota Yasuhiro 
Published: May 2020

SignificanceWe discovered that the tropical oceanic diversity depression is not a recent phenomenon nor very deep time in origin by using a comprehensive global dataset of the calcified shells of planktonic foraminifers, abundant unicellular organisms in the world's oceans, which are exceptionally well preserved in marine sediments as fossils. The diversity decline in the lowest latitudes may have started due to rapid post–ice-age warming around 15,000 y ago. Warming may by the end of this century diminish tropical oceanic diversity to an unprecedented level in human history.
In vivo mapping of a GPCR interactome using knockin mice
Authors: Degrandmaison Jade , Abdallah Khaled , Blais Véronique , Génier Samuel , Lalumière Marie-Pier , Bergeron Francis , Cahill Catherine M. , Boulter Jim , Lavoie Christine L. , Parent Jean-Luc , Gendron Louis 
Published: May 2020

Significance
G-protein–coupled receptors (GPCRs) are the target of approximately 34% of the current medications. However, their in vivo assessment remains arduous, mainly due to their structural properties, their low abundance, and the lack of highly specific antibodies. Using proteomics and unique transgenic mouse models, we reveal an in vivo GPCR interactome. We applied this approach to the δ-opioid receptor (DOPr) and identified several interactors from brain tissues. Since this procedure can be transposed to any other receptors, our work provides leads for the discovery of molecular mechanisms regulating GPCR functions in vivo.
Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus
Authors: Delaveris Corleone S. , Webster Elizabeth R. , Banik Steven M. , Boxer Steven G. , Bertozzi Carolyn R. 
Published: May 2020

Significance
Influenza A viruses cause tens of millions of cases of seasonal flu each year. Before a virus infects a host cell, it must first pass through a dense forest of sugar-bearing proteins called mucins. The basic mechanisms of how the virus navigates and chops down this forest of mucins remain up for debate, and many flu drugs target the interactions of the virus with mucin-like proteins. In this work, we make synthetic versions of mucins to create an artificial forest that can be tuned and modified at a molecular level to study how mucins impact influenza A virus binding and fusion.
The impact of story grammar instruction and text difficulty on students’ skill in summarizing narratives
Authors: Hellmann Esther , Ehri Linnea C. 
Published: May 2020

Abstract
Previous research on teaching summarizing skill has focused on summarizing strategies that are appropriate for expository
texts rather than narrative text. Findings of these studies showed an advantage for older over younger students but did not control for text
difficulty, so age effects may have been confounded by text difficulty. The present study tested an intervention designed to improve
summarizing of narrative texts, taking into account the factor of text difficulty. Thirty fourth-grade participants (mean
age = 9.7 years) were pretested for reading and summarizing skill. Participants receiving the summarizing treatment
(N = 15) were taught to write summaries of narrative texts based on story grammar components. Participants receiving the
writing control treatment (N = 15) were taught to write about connections between their lives and the text. Results showed
that the story grammar intervention improved the quality of narrative summaries and that better summaries came from easier text than harder
text. The present study reveals a shortcoming of previous summarizing studies that attributed superior performance to age without
considering text difficulty. Findings show the effectiveness of teaching fourth graders to apply story grammar components to improve their
skill in summarizing narrative text.
Comprehension and metacomprehension of negated text
Authors: Margolin Sara J. , Brackins Timothy 
Published: May 2020

AbstractPrevious research has demonstrated that negated text is a particularly difficult text construction, and often leads to readers having difficulty understanding and remembering what they have read. To date, attempts at identifying a strategy that would aid in readers’ comprehension of negation have not been successful. However, in studies focused on affirmative text, readers practicing retrieving information from a text showed improvements in comprehension and more accurate metacomprehension judgments. The present study aimed to determine whether this strategy also benefits readers of passages in which a critical concept has been negated. Interestingly, results demonstrated that while readers judged their comprehension to be better when practicing retrieval, their comprehension was not actually better. These results suggest that simply practicing retrieval information is not necessarily enough to enhance comprehension or metacomprehension of this text construction.
Through Scandinavia, Darkly: A Criminological Critique of Nordic Noir
Authors: Hayward Keith J , Hall Steve 
Published: May 2020

AbstractNordic noir is a popular crime genre associated with a region (Scandinavia), a narrative style (unpretentious/socially critical) and a particular aesthetic look (dark/foreboding). Renowned for its psychologically complex characterization and gloomy Mise-en-scène, and spanning best-selling crime fiction, film, and globally successful television drama, Nordic noir has mushroomed from regional niche market to international phenomenon in little more than a decade. A review of both popular and academic accounts of the genre suggest that much of Nordic noir’s appeal comes from its supposed ‘gritty’ or ‘realist’ account of Scandinavian society. This paper, however, adopts a different perspective. Drawing on cultural criminology, ultra-realism and Lacanian psychoanalytic theory, we argue that, rather than accurately reflecting the complex social and political problems currently confronting late modern Scandinavian welfare societies, Nordic noir has lost its grip on realism and any meaningful association with actual/established Scandinavian values. Instead, Nordic noir is now functioning as a displacement narrative, a form of cultural expression that allows artists, producers and their audiences to push the region’s social problems outside the realm even of the Imaginary.