bluuebunny/crossref_metadata_2025_split huggingface dataset:
Function of quorum sensing and cell signaling in wastewater treatment systems
Authors: Hu Huizhi , Luo Feng , Liu Yirong , Zeng Xiangguo 
Published: December 2020

AbstractQuorum sensing (QS) is a communication mode between microorganisms to regulate bacteria ecological relations and physiological behaviors, thus achieve the physiological function that single bacteria cannot complete. This phenomenon plays important roles in the formation of biofilm and granular sludge, and may be related to enhancement of some functional bacteria activity in wastewater treatment systems. There is a need to better understand bacterial QS in engineered reactors, and to assess how designs and operations might improve the removal efficiency. This article reviewed the recent advances of QS in several environmental systems and mainly analyzed the regulation mechanism of QS-based strategies for biofilm, granular sludge, functional bacteria, and biofouling control. The co-existences of multiple signal molecules in wastewater treatment (WWT) processes were also summarized, which provide basis for the future research on the QS mechanism of multiple signal molecules' interaction in WWT. This review would present some prospects and suggestions which are of practical significance for further application.
A epidemia do vírus Zika nas Ciências Sociais no Brasil: Um balanço bibliográfico (2016-2018)
Authors: Freitas Gabriela , Fleischer Soraya 
Published: December 2020

Este balanço bibliográfico compilou as contribuições das Ciências Sociais no Brasil sobre a epidemia do Zika Vírus (ZV). Foram escrutinados os materiais mais produzidos pela área: artigos, resenhas, dossiês e editoriais publicados em periódicos e capítulos publicados em livros autorais e coletâneas. Foram encontrados 38 textos publicados por cientistas sociais no período de 2016 a 2018. Discutimos os principais debates na área a cada ano para mostrar a mudança e amadurecimento dos temas. O conjunto bibliográfico revela uma maioria de pesquisadoras, vindas de centros acadêmicos do Nordeste brasileiro e cobrindo principalmente os assuntos sobre as famílias atingidas, as políticas públicas, as mídias, a deficiência e as terapias reabilitadoras.
Palavras-chave: Zika Vírus. Síndrome Congênita do Vírus Zika. Ciências Sociais. Brasil. Estudo bibliográfico.
An Efficacy and Safety Study of Remogliflozin in Obese Indian Type 2 Diabetes Mellitus Patients Who Were Inadequately Controlled on Insulin Glargine Plus other Oral Hypoglycemic Agents
Authors: Shankar Anand 
Published: December 2020

Aim & Objective:The objective of this retrospective study was to investigate the efficacy of adding remogliflozin to current insulin glargine plus two oral drug i.e. metformin and teneligliptin therapy in poorly controlled Indian type 2 diabetes.Material and Methods:173 study participants were initially selected from patient database who continued on their insulin glargine or received an increased dose of insulin glargine along with other OHA based therapy (Group A) and 187 were selected who had received remogliflozin (100 mg BD) (Group B) in addition to insulin glargine along with other OHA based therapy. Glycated haemoglobin (HbA1c), total daily insulin dose, body weight, and the number of hypoglycemic events were recorded at weeks 0, 12 and 24.Result:During the study, mean values of HbA1c, FBG and P2BG were significantly reduced in both groups. Insulin requirements decreased from 45.8 ± 16.7 IU/day to 38.5 ± 13.5 IU/day (P < 0.001) and at week 24 even further decreased to 29.5 ± 14.5 IU/Day . Twenty three patients in group B were able to cease insulin treatment altogether after 24 week treatment. It has been observed to attain tight blood glucose control we need to increase insulin dose in group A from 45.5 ± 16.5 IU/Day to 51.5 ± 14.5 at week 12 (P<0.01) and which further increased to 53.8 ± 12.8 IU/Day at week 24 (P<0.01). Adding remogliflozin showed significant effect on blood pressure (P < 0.001) and weight reduction (P < 0.001). It has been observed that 38% patients has achieves targeted HbA1c (≤7%) in group B where it was 22% in group A.Conclusion:Results demonstrate that in uncontrolled T2DM patients remogliflozin 100 mg BD can successfully lay a foundation for prolonged good glycemic control. Early addition of remogliflozin with insulin glargine plus OHAs may be an alternative compare to intensive up titration of insulin daily dose in people with uncontrolled T2DM. Clinical Trial Registration Number: A 2358
Garcinia mangostana Shell and Tradescantia spathacea Leaf Extract- Mediated One-pot Synthesis of Silver Nanoparticles with Effective Antifungal Properties
Authors: Le Ngoc Thuy Trang , Thi Thai Thanh Hoang , Ching Yern Chee , Nguyen Ngoc Hoi , Nguyen Dong Yen Pham , Truong Quynh Mong , Nguyen Dai Hai 
Published: December 2020

Background:
The feasibility of plant extracts for metallic nanoparticle fabrication has
been demonstrated. Each plant species impacts differently on formed nanoparticles, thus specific
plants need to be explored in detail.

Objective:
Continuing the fabrication of nanoparticles using green method, Garcinia mangostana
shell and Tradescantia spathacea leaf extract are exploited as reducing sources to form two types of
silver nanoparticles (GMS-AgNPs and TSL-AgNPs) less than 50 nm.

Methods:
Structural characterization of GMS-AgNPs and TSL-AgNPs was performed by ultravioletvisible
spectrophotometry (UV-vis), Fourier transform infrared spectroscopy (FTIR), X-ray energy
dispersive spectrometer (EDAX), scanning electron microscopy (SEM) and transmission electron
microscopy (TEM). Antifungal tests of GMS-AgNPs and TSL-AgNPs were performed with Aspergillus
niger, Aspergillus flavus, and Fusarium oxysporum.

Results:
UV-vis spectra with the 440-nm peak demonstrate the silver nanoparticle formation. FTIR
analysis shows the GMS-AgNPs and TSL-AgNPs modified by organic functional groups. The SEM
and TEM images indicate that the GMS-AgNPs are spherical shaped with rough edged, while the
TSL-AgNPs are spherical shape with smooth surface. The GMS-AgNP average size (15.8 nm) is
smaller than TSL-AgNP (22.4 nm). In addition, antifungal tests using Aspergillus niger, Aspergillus
flavus, and Fusarium oxysporum reveal that GMS-AgNPs and TSL-AgNPs can significantly inhibit
the proliferation of these fungal strains.

Conclusion:
Garcinia mangostana shell and Tradescantia spathacea leaf extract as renewable and
eco-friendly resources playing a dual role for nanoparticle biosynthesis create GMS-AgNPs and
TSL-AgNPs with high antifungal efficiency for biomedical or agricultural applications.
A Review of Minimum Quantity Lubrication (MQL) Based on Bibliometry
Authors: Gaurav Gaurav , Sharma Abhay , Dangayach Govind Sharan , Meena Makkhan Lal 
Published: December 2020

Background:
Minimum quantity lubrication (MQL) is one of the most promising machining
techniques that can yield a reduction in consumption of cutting fluid by more than 90 %
while ensuring the surface quality and tool life. The significance of the MQL in machining makes
it imperative to consolidate and analyse the current direction and status of research in MQL.

Objective:
This study aims to assess global research publication trends and hot topics in the field of
MQL among machining processes. The bibliometric and descriptive analysis are the tools that the
investigation aims to use for the data analysis of related literature collected from Scopus databases.

Methods:
Various performance parameters are extracted, such as document types and languages of
publication, annual scientific production, total documents, total citations, and citations per article.
The top 20 of the most relevant and productive sources, authors, affiliations, countries, word cloud,
and word dynamics are assessed. The graphical visualisation of the bibliometric data is presented
in terms of bibliographic coupling, citation, and co-citation network.

Results:
The investigation reveals that the International Journal of Machine Tools and Manufacture
(2611 citations, 31 h-index) is the most productive journal that publishes on MQL. The most
productive institution is the University of Michigan (32 publications), the most cited country is
Germany (1879 citations), and the most productive country in MQL is China (124 publications).
The study shows that ‘Cryogenic Machining’, ‘Sustainable Machining’, ‘Sustainability’, ‘Nanofluid’
and ‘Titanium alloy’ are the most recent keywords and indications of the hot topics and future
research directions in the MQL field.

Conclusion:
The analysis finds that MQL is progressing in publications and emerging with issues
that are strongly associated with the research. This study is expected to help the researchers to find
the most current research areas through the author’s keywords and future research directions in
MQL and thereby expand their research interests.
Heterogeneous communication system for technical control and monitoring of energy, industrial, housing and utilities, and agro-industrial facilities
Authors: Shubarev V. A. , Myakochin Yu. O. , Gusarov A. A. 
Published: December 2020

Problem statement. Automated systems for monitoring and accounting of energy resources are increasingly used in large companies and small-scale production. Specialists often face the problem of installing sensors and receiving data in rooms with thick reinforced concrete and brick walls, where it is impossible to establish reliable radio communication, and the installation of additional cables is expensive. In such conditions, heterogeneous communication systems, in which different technologies can be used for communication, prove themselves well.Objective. Determine the optimal technology for heterogeneous communication systems for installing an automated system for monitoring and accounting of energy resources in certain conditions and develop technical proposals.Results. A simulation of the physical level of the communication system was performed using a PLC-G3 protocol. The energy characteristics were modeled and evaluated using 6LoWPAN technology. Technical proposals for creating technical means of the heterogeneous communication system are developed, the architecture of technical means and the structure of heterogeneous communication system are proposed.Practical significance. An automated system for monitoring and accounting of energy resources based on a heterogeneous sensor communication system provides regular collection of accurate information about energy resources at all stages of their movement – from input at the facility to each of the end points of consumption, provides access to the collected data for analyzing the state of the system as a whole, and allows operational control of the actuators of metering and control devices.
Research of electrical characteristics of increased uniformity LAN-cables
Authors: Bulkhin A. K. , Klyuchnikov V. F. , Bannov V. V. , Popov V. B. 
Published: December 2020

Formulation of the problem. At present, symmetric LAN cables are widely used in structured cabling systems (SCS) and fixed broadband access (BBA) networks in the world and in Russia. Practical experience of using LAN cables on real broadband access networks shows that high-quality transmission can only be achieved using high-quality highly uniform cables.Objective. Study of the dependence of the quality of LAN-cables on technological equipment and the quality of materials, which provide increased cable uniformity.Results. Based on the experimental studies carried out with the use of a modern measuring system, the main electrical characteristics of the transmission and the mutual influence of the most popular four-pair LAN-cable of the 5e category of the U/UTP4×2×0.52 type in the frequency range up to 100 MHz are determined. It is shown that to ensure high and stable transmission characteristics and mutual influence, modern technological equipment must be equipped with cable quality parameters automatic control systems and it is necessary to choose reliable suppliers when using domestic production materials.Practical significance. For the effective practical use of LAN cables on fixed broadband access networks and in SCS, it is very important to have high stability of electrical characteristics and their compliance with rather high established standards. This is possible only by ensuring high geometric and structural homogeneity of the structural elements of LAN cables.
Comprehensive solution for onboard fiber-optic information networks
Authors: Andreev V. A. , Bourdine A. V. , Burdin V. A. 
Published: December 2020

Problem statement. In recent years, the problem of replacing copper-core fiber-optic cables has become particularly relevant. This is due to two factors: first, the prospect of introducing unmanned vehicles and the development of electromagnetic microwave weapons that can disable electronic equipment for almost any target at a distance of 10 km or more, and second, the growing need to reduce the delay of transmitted signals on the network and increase the volume of information transmitted in these networks. The article describes the construction of onboard cable networks using fiberoptic cables. The advantages and disadvantages of fiber-optic based onboard networks are described.Objective. Development of solutions for the use of fiber-optic communication cables in onboard information networks that provide high technology for laying optical cables, the required speed of information transmission, ease of operation and modernization of information networks.Results. A comprehensive solution for building onboard information networks based on fiber-optic cables having an increased core diameter and an optimized refractive index profile in pipelines using pneumatic laying technology is proposed.Practical implications. The proposed integrated solution for onboard fiber-optic information networks, including a method for onboard laying optical cables, the use of specially developed optical fiber with an increased core diameter and reduced differential modal delay, and the development of modular telecommunications equipment, allows meeting the requirements for onboard networks to ensure reliability and safety, economic efficiency, reduce labor intensity, and ease of maintenance, components dismantling and replacement.
Relationship Between Diabetes, Stress, and Self-Management to Inform Chronic Disease Product Development: Retrospective Cross-Sectional Study
Authors: Yu Jessica S , Xu Tong , James Roberta A , Lu Wei , Hoffman Julia E 
Published: December 2020

Background
Technology is rapidly advancing our understanding of how people with diabetes mellitus experience stress.

Objective
The aim of this study was to explore the relationship between stress and sequelae of diabetes mellitus within a unique data set composed of adults enrolled in a digital diabetes management program, Livongo, in order to inform intervention and product development.

Methods
Participants included 3263 adults under age 65 who were diagnosed with diabetes mellitus and had access to Livongo through their employer between June 2015 and August 2018. Data were collected at time of enrollment and 12 months thereafter, which included demographic information, glycemic control, presence of stress, diabetes distress, diabetes empowerment, behavioral health diagnosis, and utilization of behavioral health-related medication and services. Analysis of variance and chi-square tests compared variables across groups that were based on presence of stress and behavioral health diagnosis or utilization.

Results
Fifty-five percent of participants (1808/3263) reported stress at the time of at least 1 blood glucose reading. Fifty-two percent of participants (940/1808) also received at least 1 behavioral health diagnosis or intervention. Compared to their peers, participants with stress reported greater diabetes distress, lower diabetes empowerment, greater insulin use, and poorer glycemic control. Participants with stress and a behavioral health diagnosis/utilization additionally had higher body mass index and duration of illness.

Conclusions
Stress among people with diabetes mellitus is associated with reduced emotional and physical health. Digital products that focus on the whole person by offering both diabetes mellitus self-management tools and behavioral health skills and support can help improve disease-specific and psychosocial outcomes.
Physiological Responses and User Feedback on a Gameful Breathing Training App: Within-Subject Experiment
Authors: Lukic Yanick Xavier , Shih Chen-Hsuan (Iris) , Hernandez Reguera Alvaro , Cotti Amanda , Fleisch Elgar , Kowatsch Tobias 
Published: December 2020

BackgroundSlow-paced breathing training (6 breaths per minute [BPM]) improves physiological and psychological well-being by inducing relaxation characterized by increased heart rate variability (HRV). However, classic breathing training has a limited target group, and retention rates are very low. Although a gameful approach may help overcome these challenges, it is crucial to enable breathing training in a scalable context (eg, smartphone only) and ensure that they remain effective. However, despite the health benefits, no validated mobile gameful breathing training featuring a biofeedback component based on breathing seems to exist.ObjectiveThis study aims to describe the design choices and their implementation in a concrete mobile gameful breathing training app. Furthermore, it aims to deliver an initial validation of the efficacy of the resulting app.MethodsPrevious work was used to derive informed design choices, which, in turn, were applied to build the gameful breathing training app Breeze. In a pretest (n=3), design weaknesses in Breeze were identified, and Breeze was adjusted accordingly. The app was then evaluated in a pilot study (n=16). To ascertain that the effectiveness was maintained, recordings of breathing rates and HRV-derived measures (eg, root mean square of the successive differences [RMSSDs]) were collected. We compared 3 stages: baseline, standard breathing training deployed on a smartphone, and Breeze.ResultsOverall, 5 design choices were made: use of cool colors, natural settings, tightly incorporated game elements, game mechanics reflecting physiological measures, and a light narrative and progression model. Breeze was effective, as it resulted in a slow-paced breathing rate of 6 BPM, which, in turn, resulted in significantly increased HRV measures compared with baseline (P<.001 for RMSSD). In general, the app was perceived positively by the participants. However, some criticized the somewhat weaker clarity of the breathing instructions when compared with a standard breathing training app.ConclusionsThe implemented breathing training app Breeze maintained its efficacy despite the use of game elements. Moreover, the app was positively perceived by participants although there was room for improvement.
The Use of Telehealth Technology to Support Health Coaching for Older Adults: Literature Review
Authors: Markert Carl , Sasangohar Farzan , Mortazavi Bobak J , Fields Sherecce 
Published: December 2020

Background
Health coaching is an intervention process for driving behavior change through goal-setting, education, encouragement, and feedback on health-related behaviors. Telehealth systems that include health coaching and remote monitoring are making inroads in managing chronic conditions and may be especially suited for older populations.

Objective
This literature review aimed to investigate the current status of health coaching interventions incorporating telehealth technology and the associated effectiveness of this intervention to deliver health care with an emphasis on older adults (aged 65 and older).

Methods
A literature review was conducted to identify the research conducted on health coaching combined with remote monitoring for delivering health care to older adults. The Ovid MEDLINE and CINAHL databases were queried using a combination of relevant search terms (including middle aged, aged, older adult, elderly, health coaching, and wellness coaching). The search retrieved 196 papers published from January 2010 to September 2019 in English. Following a systematic review process, the titles and abstracts of the papers retrieved were screened for applicability to health coaching for older adults to define a subset for further review. Papers were excluded if the studied population did not include older adults. The full text of the 42 papers in this subset was then reviewed, and 13 papers related to health coaching combined with remote monitoring for older adults were included in this review.

Results
Of the 13 studies reviewed, 10 found coaching supported by telehealth technology to provide effective outcomes. Effectiveness outcomes assessed in the studies included hospital admissions/re-admissions, mortality, hemoglobin A1c (HbA1c) level, body weight, blood pressure, physical activity level, fatigue, quality of life, and user acceptance of the coaching program and technology.

Conclusions
Telehealth systems that include health coaching have been implemented in older populations as a viable intervention method for managing chronic conditions with mixed results. Health coaching combined with telehealth may be an effective solution for providing health care to older adults. However, health coaching is predominantly performed by human coaches with limited use of technology to augment or replace the human coach. The opportunity exists to expand health coaching to include automated coaching.