bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bringing asthma care into the twenty-first century
Authors: Larsson Kjell , Kankaanranta Hannu , Janson Christer , Lehtimäki Lauri , Ställberg Björn , Løkke Anders , Høines Kristian , Roslind Klaus , Ulrik Charlotte Suppli 
Published: June 2020

AbstractDespite access to diagnostic tests and effective therapies, asthma often remains misdiagnosed and/or poorly controlled or uncontrolled. In this review, we address the key issues of asthma diagnosis and management, recent evidence for levels of asthma control, the consequences of poor control and, in line with that, explore the potential reasons for poor asthma control and acute exacerbations. Based on recent evidence and current guidelines, we also aim to provide practical answers to the key questions of how to improve asthma management, with the best possible prevention of exacerbations, addressing the basics—adherence, inhaler misuse, obesity and smoking—and how to facilitate a new era of asthma care in the twenty-first century. We hope this review will be useful to busy primary care clinicians in their future interactions with their patients with both suspected and proven asthma.
HISTOBREAST, a collection of brightfield microscopy images of Haematoxylin and Eosin stained breast tissue
Authors: Buga Roxana M. , Totu Tiberiu , Dumitru Adrian , Costache Mariana , Floroiu Iustin , Sladoje Nataša , Stanciu Stefan G. 
Published: June 2020

AbstractModern histopathology workflows rely on the digitization of histology slides. The quality of the resulting digital representations, in the form of histology slide image mosaics, depends on various specific acquisition conditions and on the image processing steps that underlie the generation of the final mosaic, e.g. registration and blending of the contained image tiles. We introduce HISTOBREAST, an extensive collection of brightfield microscopy images that we collected in a principled manner under different acquisition conditions on Haematoxylin - Eosin (H&E) stained breast tissue. HISTOBREAST is comprised of neighbour image tiles and ensemble of mosaics composed from different combinations of the available image tiles, exhibiting progressively degraded quality levels. HISTOBREAST can be used to benchmark image processing and computer vision techniques with respect to their robustness to image modifications specific to brightfield microscopy of H&E stained tissues. Furthermore, HISTOBREAST can serve in the development of new image processing methods, with the purpose of ensuring robustness to typical image artefacts that raise interpretation problems for expert histopathologists and affect the results of computerized image analysis.
Photographic database of the European cave salamanders, genus Hydromantes
Authors: Lunghi Enrico , Giachello Simone , Zhao Yahui , Corti Claudia , Ficetola Gentile Francesco , Manenti Raoul 
Published: June 2020

AbstractEuropean Hydromantes are a group of eight salamander species often occurring in subterranean habitats, which are a difficult environment to explore. All Hydromantes are strictly protected species and thus, low-impact methodologies to study these salamanders are strongly needed. Here we used a photographic technique to produce a large dataset of European Hydromantes, providing standardised pictures of 1,052 individuals belonging to the eight species, including hybrids as well. With our methodology we were able to reduce the handling time of individuals, and produce high quality pictures useful to investigate multiple life traits of these endangered species. Furthermore, the standardised photos provided here can be used for future comparisons of individuals from the surveyed populations.
The Project Baseline Health Study: a step towards a broader mission to map human health
Authors: Arges Kristine , Assimes Themistocles , Bajaj Vikram , Balu Suresh , Bashir Mustafa R. , Beskow Laura , Blanco Rosalia , Califf Robert , Campbell Paul , Carin Larry , Christian Victoria , Cousins Scott , Das Millie , Dockery Marie , Douglas Pamela S. , Dunham Ashley , Eckstrand Julie , Fleischmann Dominik , Ford Emily , Fraulo Elizabeth , French John , Gambhir Sanjiv S. , Ginsburg Geoffrey S. , Green Robert C. , Haddad Francois , Hernandez Adrian , Hernandez John , Huang Erich S. , Jaffe Glenn , King Daniel , Koweek Lynne H. , Langlotz Curtis , Liao Yaping J. , Mahaffey Kenneth W. , Marcom Kelly , Marks William J. , Maron David , McCabe Reid , McCall Shannon , McCue Rebecca , Mega Jessica , Miller David , Muhlbaier Lawrence H. , Munshi Rajan , Newby L. Kristin , Pak-Harvey Ezra , Patrick-Lake Bray , Pencina Michael , Peterson Eric D. , Rodriguez Fatima , Shore Scarlet , Shah Svati , Shipes Steven , Sledge George , Spielman Susie , Spitler Ryan , Schaack Terry , Swamy Geeta , Willemink Martin J. , Wong Charlene A. 
Published: June 2020

AbstractThe Project Baseline Health Study (PBHS) was launched to map human health through a comprehensive understanding of both the health of an individual and how it relates to the broader population. The study will contribute to the creation of a biomedical information system that accounts for the highly complex interplay of biological, behavioral, environmental, and social systems. The PBHS is a prospective, multicenter, longitudinal cohort study that aims to enroll thousands of participants with diverse backgrounds who are representative of the entire health spectrum. Enrolled participants will be evaluated serially using clinical, molecular, imaging, sensor, self-reported, behavioral, psychological, environmental, and other health-related measurements. An initial deeply phenotyped cohort will inform the development of a large, expanded virtual cohort. The PBHS will contribute to precision health and medicine by integrating state of the art testing, longitudinal monitoring and participant engagement, and by contributing to the development of an improved platform for data sharing and analysis.
An evolutionarily conserved motif is required for Plasmodesmata-located protein 5 to regulate cell-to-cell movement
Authors: Wang Xu , Robles Luna Gabriel , Arighi Cecilia Noemi , Lee Jung-Youn 
Published: June 2020

AbstractNumerous cell surface receptors and receptor-like proteins (RLPs) undergo activation or deactivation via a transmembrane domain (TMD). A subset of plant RLPs distinctively localizes to the plasma membrane-lined pores called plasmodesmata. Those RLPs include the Arabidopsis thaliana Plasmodesmata-located protein (PDLP) 5, which is well known for its vital function regulating plasmodesmal gating and molecular movement between cells. In this study, we report that the TMD, although not a determining factor for the plasmodesmal targeting, serves essential roles for the PDLP5 function. In addition to its role for membrane anchoring, the TMD mediates PDLP5 self-interaction and carries an evolutionarily conserved motif that is essential for PDLP5 to regulate cell-to-cell movement. Computational modeling-based analyses suggest that PDLP TMDs have high propensities to dimerize. We discuss how a specific mode(s) of TMD dimerization might serve as a common mechanism for PDLP5 and other PDLP members to regulate cell-to-cell movement.
Negative photoconductivity in Cs4PbBr6 single crystal
Authors: Yuan Ye , Yao Qing , Zhang Jie , Wang Kaiyu , Zhang Weiwei , Zhou Tianliang , Sun Haiqing , Ding Jianxu 
Published: June 2020

Negative photoconductivity is firstly observed in large size Cs4PbBr6 single crystal that grown from Cs-rich solution. The Br vacancy and free excitons are responsible for this novel phenomena.
Effectiveness of Hearing Loss Prevention Education for Active Duty Military Personnel: A Preliminary Study
Authors: Beamer Sharon , Gagne Catherine , Chada Nutan , Mehta Hina , Piper Sheila , Wong Geoffrey , Davila Gabriel 
Published: June 2020

Purpose
The combination of effective hearing health education and hearing protection establishes a strong foundation of hearing loss prevention efforts in the military; however, it is not clear which elements of the educational materials used in hearing loss prevention programs are the most effective in preventing noise-induced hearing loss. To explore this question, a cohort of Excellence in Government Fellowship participants and the Army Hearing Program conducted a preliminary study examining two hearing health education materials.

Method
A convenience sample of active duty personnel reviewed a hearing health education Technical Guide and video, developed by the military for hearing conservation programs. A “pre- and posteducation” questionnaire was administered to assess the participants' knowledge regarding hearing protection, causes of noise-induced hearing loss, effects of noise on hearing, noise exposure both on and off duty, and satisfaction with educational materials provided during the session.

Results
Short-term learning effects from the educational materials was achieved for some knowledge-based items (> 10% change from pre-education to posteducation), particularly for questions related to the effect of noise-induced hearing loss on ability to hear speech or hear at a distance. Thirty five percent of study participants reported using hearing protection in hazardous noise 75%–100% of the time. Primary reason for not using hearing protection was comfort.

Conclusions
Despite hearing loss prevention efforts in the military, hearing loss and tinnitus (ringing in the ears) continue to be prevalent service-connected disabilities among veterans. This study offers some insights regarding current hearing loss prevention understanding and practices for a group of active duty U.S. military personnel. Results from this study can inform future improvements in military hearing loss prevention education.
COVID-19: Monitoring the propagation of the first waves of the pandemic
Authors: Knafo William 
Published: June 2020

Introduction: A phenomenological approach is proposed to monitor the propagation of the first waves of the COVID-19 pandemic.Method: A large set of data collected during the first months of 2020 is compiled into a series of semi-logarithmic plots, for a selection of 32 countries from the five continents.Results: Three regimes are identified in the propagation of an epidemic wave: a pre-epidemic regime 1, an exponential-growth regime 2, and a resorption regime 3. A two-parameters scaling of the first-wave death variation reported in China is used to fit the first-wave data reported in other countries. Comparison is made between the propagation of the pandemic in different countries, which are classified into four groups, from Group A where the pandemic first waves were contained efficiently, to Group D where the pandemic first waves widely spread. All Asian countries considered here, where fast and efficient measures have been applied, are in Group A. Group D is composed of Western-European countries and the United States of America (USA), where late decisions and confused political communication (pandemic seriousness, protection masks, herd immunity, etc.) led to a large number of deaths.Discussion:The threat of resurging epidemic waves following a lift of lockdown measures is discussed. The results obtained in Asian countries from group A, as Hong Kong and South Korea, are highlighted, and the measures taken there are presented as examples that other countries may follow.
Intra- und paraselläre Prozesse – eine Übersicht
Authors: Raab Peter , Götz G. Friedrich 
Published: June 2020

ZusammenfassungFunktionsstörungen der Hypophyse, Gesichtsfelddefekte und Augenbewegungsstörungen sind typische Leitsymptome bei Erkrankungen der Sellaregion. Die Diagnose der jeweiligen Erkrankung und die Therapieplanung sind unter Berücksichtigung der komplexen lokalen Anatomie häufig herausfordernd. Diese Übersichtsarbeit beschreibt Untersuchungsmethoden und typische Befundmuster, die eine Diagnose sowie die zielführende Therapieplanung erleichtern sollen.
Hygienisch-mikrobiologische Evaluation von Tuchspendersystemen zur
Oberflächendesinfektion im alltäglichen
Klinikbetrieb
Authors: Blume Philipp , Chaberny Iris 
Published: June 2020

Zusammenfassung
Hintergrund Oberflächendesinfektion zählt zu den
elementaren Maßnahmen der Infektionsprävention in
Gesundheitseinrichtungen. Die hierfür heutzutage weit verbreiteten
Tuchspendersysteme können jedoch aufgrund unterschiedlicher Ursachen
mikrobiell kontaminiert sein und bei der Verbreitung von Krankheitserregern eine
entscheidende Rolle spielen. Aus diesem Grund müssen diese Systeme
sowohl in die routinemäßige Surveillance, als auch im Rahmen
nosokomialer Ausbrüche als Infektionsquelle in Betracht gezogen
werden.
Methodik Die am Universitätsklinikum Leipzig (UKL) verwendeten
Tuchspendersysteme wurden von 2016 bis 2018 flächendeckend
gemäß der Empfehlung des Verbundes für Angewandte
Hygiene (VAH) überprüft. Innerhalb dieses Zeitraums wurden
insgesamt 1096 Desinfektionslösungen von Tuchspendersystemen analysiert.
Die Bereiche ohne bzw. mit besonderem Infektionsrisiko waren hierbei
gleichverteilt repräsentiert. Um die Möglichkeit einer
Kontamination durch Dosiergeräte (DG) auszuschließen, wurden die
hygienischen Prüfungen auf die 135 dezentral-betriebenen DGs am UKL
erweitert.
Ergebnisse Grundsätzlich konnte ein Rückgang von
kontaminierten Desinfektionslösungen im gesamten Untersuchungszeitraum
verzeichnet werden (2016: 31%; 2017: 18%; 2018: 8%).
Jedoch wurden sowohl 2017, als auch 2018 mehr Kontaminationen in Bereichen mit
besonderem Infektionsrisiko festgestellt. Gezielte Nachuntersuchungen nach
Schulungsmaßnahmen im Umgang und Aufbereitung der Systeme ergaben einen
Rückgang positiver Desinfektionslösungen auf Stationen mit
erhöhten Nachweisen. Das mikrobielle Spektrum wurde von Achromobacter
spp. (81%) dominiert, gefolgt von Pseudomonas spp.
(10%), Vancomycin-resistente Enterokokken (VRE) (4%) und
apathogenen Umwelterregern (5%). Die aus den Dosiergeräten
(n=135) entnommenen Lösungen zeigten in 91,1% keinerlei
Wachstum. In 8,2% wurden Bacillus spp. und in 0,7%
Schimmelpilze nachgewiesen.
Schlussfolgerung Als Ursache für die Erregernachweise in
Tuchspendersystemen konnte eine Kontamination aus Dosiergeräten, als
auch des hierfür verwendeten Trinkwassers ausgeschlossen werden. Es ist
davon auszugehen, dass mangelnde Kenntnisse und ein falsches
Sicherheitsgefühl beim Umgang mit Desinfektionsmitteln zu inkorrekter
Handhabung von Tuchspendersystemen führen.
Spatial distribution of dysplasia in Barrett’s esophagus segments before and after endoscopic ablation therapy: a meta-analysis
Authors: Garg Shashank , Xie Jesse , Inamdar Sumant , Thomas Sheila L. , Trindade Arvind J. 
Published: June 2020

Background Dysplasia in Barrett’s esophagus (BE) is focal and difficult to locate. The aim of this meta-analysis was to understand the spatial distribution of dysplasia in BE before and after endoscopic ablation therapy.
Methods A systematic search was performed of multiple databases to July 2019. The location of dysplasia prior to ablation was determined using a clock-face orientation (right or left half of the esophagus). The location of the dysplasia post-ablation was classified as within the tubular esophagus or at the top of the gastric folds (TGF).
Results 13 studies with 2234 patients were analyzed. Pooled analysis from six studies (819 lesions in 802 patients) showed that before ablation, dysplasia was more commonly located in the right half versus the left half (odds ratio [OR] 4.3; 95 % confidence interval [CI] 2.33 – 7.93; P < 0.001). Pooled analysis from seven studies showed that dysplasia after ablation recurred in 101 /1432 patients (7.05 %; 95 %CI 5.7 % – 8.4 %). Recurrence of dysplasia was located more commonly at the TGF (n = 68) than in the tubular esophagus (n = 34; OR 5.33; 95 %CI 1.75 – 16.21; P = 0.003). Of the esophageal lesions, 90 % (27 /30) were visible, whereas only 46 % (23 /50) of the recurrent dysplastic lesions at the TGF were visible (P < 0.001).
Conclusion Before ablation, dysplasia in BE is found more frequently in the right half of the esophagus versus the left. Post-ablation recurrence is more commonly found in the TGF and is non-visible, compared with the tubular esophagus, which is mainly visible.
Cesarean Section in Patients with Myomas Located on the Anterior Wall of the Cervix
Authors: Hiramatsu Yuji 
Published: June 2020

AbstractIn patients with uterine myomas undergoing cesarean section, the site of the uterine incision differs depending on the location, size, and number of myomas and the location of the placenta. The difficulty is particularly high when the myomas are located on the anterior wall of the cervix. In all patients, safe fetal birth is the top priority. The incision is usually made to avoid uterine myomas, and enucleation of the myomas is performed after fetal birth. However, in some patients, the fetus must be delivered after enucleating the myomas, so practice is necessary to be prepared for such cases. In this report, I explain the critical points to be noted at the time of cesarean section, especially in patients with myomas located on the anterior wall of the cervix.
Enhanced receptor binding of SARS-CoV-2 through networks of hydrogen-bonding and hydrophobic interactions
Authors: Wang Yingjie , Liu Meiyi , Gao Jiali 
Published: June 2020

Significance
Enhanced receptor binding by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is believed to contribute to the highly contagious transmission rate of coronavirus disease 2019. An understanding of the structural and energetic details responsible for protein–protein interactions between the host receptor ACE2 and SARS-CoV-2 can be useful to epidemic surveillance, diagnosis, and optimization of neutralizing agents. The present study unravels a delicate balance of specific and nonspecific hydrogen-bonding and hydrophobic networks to help elucidate the similarities and differences in receptor binding by SARS-CoV-2 and SARS-CoV.
Building in language support in a Hong Kong CLIL chemistry classroom
Authors: Tsang Michael Kai-yip 
Published: June 2020

AbstractScience writing has played a crucial part in science assessments. This paper reports a study in an area that has received little research attention – how science lessons in content and language integrated learning (CLIL) can increase the science knowledge development of English as a foreign language (EFL) students in Hong Kong. The data come from a school-based interventional study in chemistry classrooms, with written data from questionnaires, assessments and teachers’ logs and verbal data from interviews and classroom observations. The effectiveness of the CLIL teaching and learning activities in various chemistry classrooms were compared and evaluated, with a discussion of some implications. The paper concludes that CLIL teaching and learning activities yielded positive learning outcomes among chemistry learners with low English ability.
Aggression in media-sharing websites in the context of Greek political/parliamentary discourse in the years of the economic crisis
Authors: Georgalidou Marianthi , Frantzi Katerina T. , Giakoumakis Giorgos 
Published: June 2020

Abstract
In the context of the Greek economic crisis during the years 2009–2019, the aim of the present study is to discuss
language aggression and derogatory forms of speech attested in user polylogues commenting on instances of parliamentary discourse
uploaded to computer mediated communication networks. Within the framework of (im)politeness research (Culpeper 2005, 2011; Garcés-Conejos Blitvich 2010a; Haugh 2013; Lorenzo-Dus, et al. 2011; Mitchell and Haugh 2015), we
investigate the correlation between impoliteness and abusive verbal discourse in both domains, i.e. parliamentary sittings and
social media commentary. We explore their potential to establish a common ground in viewing political issues and determining
ideological polarizations. We also attempt a preliminary analysis of swear words and derogatory references to Greek political
personnel and their instrumentalisation for the division of the readership into those who support and those who oppose different
political agendas.
1916
Authors: Bigliazzi Silvia 
Published: June 2020

Abstract
The essay argues that Shakespeare’s Tercentenary in 1916, following the peak of his popularity on the nineteenth-century Italian stages, coincided with a peculiar cultural and political transition in Italy due to Italy’s ‘embarrassing’ entry into the war alongside the Entente in 1915. By proceeding from a discussion of the Italian contributions to Israel Gollancz’s 1916 A Book of Homage to Shakespeare, and their discursive strategies complying, but also competing, with the book’s imperialist design, to an exploration of the 1916 issue of the Florentine literary magazine Il Marzocco devoted to a celebration of Shakespeare, this chapter explores how Shakespeare was ‘narrativised’ into a multi-faceted political icon. It discusses the manners of silencing, but also exposing, his subversive potential in the context of the Tercentenary, exhibiting the manipulative force of memory and forgetfulness at a time of sudden political and cultural changes which reflect a crisis of national identity.
The translator
Authors: Saldanha Gabriela 
Published: June 2020

Abstract
This article proposes that in order to understand the nature of literary translation as an art form, we need to
complement existing approaches drawing on literary, linguistic and sociological theories with insights derived from performance
studies. As a way of exploring what the theorization of translation as performance art could contribute to our understanding of
literary translation, I map four basic tenets of performance as restored behavior (Schechner
1985) to two translators’ (Margaret Jull Costa and Peter Bush) accounts of their practice. The mapping is illustrated
with writings by and interviews with the translators, focusing on four points of contact: the unresolved dialectal tension between
self and other, the deliberate, rehearsed nature of decisions, the need for distance between original and performance/translation,
and the role of the audience.
Supplementary comparison of instrument current transformers
Authors: Santos Alejandro , Slomovitz Daniel , Aristoy Gonzalo , Sandler Rogelio , Casais Jose Luis , Olivera Patricia Casi de , Triana Alvaro Zipaquira , Gonzalez Julio , Marquez Sergio Ochoa , Mohns Enrico 
Published: June 2020

This report describes a supplementary comparison on current ratio at power frequencies. The traveling standard was a high precision current transformer. Frequencies of 50 Hz and 60 Hz were used with a current range between 5 A and 1000 A. Participants belong to SIM, except the national metrology institute of Germany, PTB, that belongs to EURAMET. The pilot institute was UTE, from Uruguay. The measurement results and uncertainties from all national metrology institutes, that have declared CMCs, were in agreement with them. The schedule had long delays due to customs procedures, but had no influence on the results due to the very high stability of the traveling transformer.

Main text

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The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).