bluuebunny/crossref_metadata_2025_split huggingface dataset:
A new biocompatible ternary Layered Double Hydroxide Adsorbent for ultrafast removal of anionic organic dyes
Authors: Rathee Garima , Awasthi Amardeep , Sood Damini , Tomar Ravi , Tomar Vartika , Chandra Ramesh 
Published: November 2019

AbstractIt would be of great significance to introduce a new biocompatible Layered Double Hydroxide (LDH) for the efficient remediation of wastewater. Herein, we designed a facile, biocompatible and environmental friendly layered double hydroxide (LDH) of NiFeTi for the very first time by the hydrothermal route. The materialization of NiFeTi LDH was confirmed by FTIR, XRD and Raman studies. BET results revealed the high surface area (106 m2/g) and the morphological studies (FESEM and TEM) portrayed the sheets-like structure of NiFeTi nanoparticles. The material so obtained was employed as an efficient adsorbent for the removal of organic dyes from synthetic waste water. The dye removal study showed >96% efficiency for the removal of methyl orange, congo red, methyl blue and orange G, which revealed the superiority of material for decontamination of waste water. The maximum removal (90%) of dyes was attained within 2 min of initiation of the adsorption process which supported the ultrafast removal efficiency. This ultrafast removal efficiency was attributed to high surface area and large concentration of -OH and CO32− groups present in NiFeTi LDH. In addition, the reusability was also performed up to three cycles with 96, 90 and 88% efficiency for methyl orange. Furthermore, the biocompatibility test on MHS cell lines were also carried which revealed the non-toxic nature of NiFeTi LDH at lower concentration (100% cell viability at 15.6 μg/ml). Overall, we offer a facile surfactant free method for the synthesis of NiFeTi LDH which is efficient for decontamination of anionic dyes from water and also non-toxic.
How formaldehyde reacts with amino acids
Authors: Kamps Jos J. A. G. , Hopkinson Richard J. , Schofield Christopher J. , Claridge Timothy D. W. 
Published: November 2019

AbstractFormaldehyde is a biological electrophile produced via processes including enzymatic demethylation. Despite its apparent simplicity, the reactions of formaldehyde with even basic biological components are incompletely defined. Here we report NMR-based studies on the reactions of formaldehyde with common proteinogenic and other nucleophilic amino acids. The results reveal formaldehyde reacts at different rates, forming hydroxymethylated, cyclised, cross-linked, or disproportionated products of varying stabilities. Of the tested common amino acids, cysteine reacts most efficiently, forming a stable thiazolidine. The reaction with lysine is less efficient; low levels of an Nε-methylated product are observed, raising the possibility of non-enzymatic lysine methylation by formaldehyde. Reactions with formaldehyde are faster than reactions with other tested biological carbonyl compounds, and the adducts are also more stable. The results reveal reactions of formaldehyde with amino acids, and by extension peptides and proteins, have potential roles in healthy and diseased biology, as well as in evolution.
Reciprocity between local moments and collective magnetic excitations in the phase diagram of BaFe2(As1−xPx)2
Authors: Pelliciari Jonathan , Ishii Kenji , Huang Yaobo , Dantz Marcus , Lu Xingye , Olalde-Velasco Paul , Strocov Vladimir N. , Kasahara Shigeru , Xing Lingyi , Wang Xiancheng , Jin Changqing , Matsuda Yuji , Shibauchi Takasada , Das Tanmoy , Schmitt Thorsten 
Published: November 2019

AbstractUnconventional superconductivity arises at the border between the strong coupling regime with local magnetic moments and the weak coupling regime with itinerant electrons, and stems from the physics of criticality that dissects the two. Unveiling the nature of the quasiparticles close to quantum criticality is fundamental to understand the phase diagram of quantum materials. Here, using resonant inelastic x-ray scattering (RIXS) and $${\rm{Fe}}-{{\rm{K}}}_{\beta }$$
Fe
−

K

β

emission spectroscopy (XES), we visualize the coexistence and evolution of local magnetic moments and collective spin excitations across the superconducting dome in isovalently-doped BaFe$${}_{2}$$

2

(As$${}_{1-x}$$

1
−
x

P$${}_{x}$$

x

)$${}_{2}$$

2

(0.00 $$ \le $$
≤
x $$\le 0.52$$
≤
0.52
). Collective magnetic excitations resolved by RIXS are gradually hardened, whereas XES reveals a strong suppression of the local magnetic moment upon doping. This relationship is captured by an intermediate coupling theory, explicitly accounting for the partially localized and itinerant nature of the electrons in Fe pnictides. Finally, our work identifies a local-itinerant spin fluctuations channel through which the local moments transfer spin excitations to the particle-hole (paramagnons) continuum across the superconducting dome.
DNA methylation analysis for screening and diagnostic testing in neurodevelopmental disorders
Authors: Godler David E. , Amor David J. 
Published: November 2019

Abstract
DNA methylation (mDNA) plays an important role in the pathogenesis of neurodevelopmental disorders (NDDs), however its use in diagnostic testing has been largely restricted to a handful of methods for locus-specific analysis in monogenic syndromes. Recent studies employing genome-wide methylation analysis (GWMA) have explored utility of a single array-based test to detect methylation changes in probands negative by exome sequencing, and to diagnose different monogenic NDDs with defined epigenetic signatures. While this may be a more efficient approach, several significant barriers remain. These include non-uniform and low coverage of regulatory regions that may have CG-rich sequences, and lower analytical sensitivity as compared with locus-specific analyses that may result in methylation mosaicism not being detected. A major challenge associated with the above technologies, regardless of whether the analysis is locus specific or genome wide, is the technical bias introduced by indirect analysis of methylation. This review summarizes evidence from the most recent studies in this field and discusses future directions, including direct analysis of methylation using long-read technologies and detection of 5-methylcytosine (5-mC or total mDNA) and 5-hydroxymethylacytosine (5-hmC) as biomarkers of NDDs.
Compact wideband four‐element MIMO antenna with high isolation
Authors: Kumar Saurabh A. , Singh Rathore P. , Kumar Meshram M. 
Published: November 2019

A compact wideband four‐element multiple‐input‐multiple‐output (MIMO) antenna with high isolation is proposed in this Letter. The proposed MIMO antenna consists of a tapered microstrip line fed rectangular monopole antenna arranged in orthogonal symmetric fashion on the interconnected partial ground plane. The overall size of the proposed antenna is 35 × 35 × 0.8 mm3 with 9.5 mm edge‐to‐edge separation between a pair of radiating elements. The proposed MIMO antenna has a −10 dB fractional impedance bandwidth of 49.57% covering 4.4–7.3 GHz, encompassing sub‐6 GHz 5G (4.5 GHz), WLAN (5/5.2/5.8 GHz), WiMAX (5.5 GHz), HYPERLAN/1, 2, and ISM bands (5.2/5.8 GHz) applications. The proposed MIMO antenna has a minimum isolation value of 21 dB, maximum envelope correlation coefficient (ECC) value of 0.014 between antenna elements throughout the band. The measured results are found in good agreement with the simulated S‐parameters, radiation patterns, ECC, total active reflection coefficient, and channel capacity loss.
Research progress of semiconductive shielding layer of HVDC cable
Authors: Wei Yanhui , Han Wang , Li Guochang , Lei Qingquan , Fu Mingli , Hao Chuncheng , Zhang Guanjun 
Published: November 2019

As an indispensable part of high‐voltage direct current (HVDC) cable, the semiconductive shielding layer plays the role of uniforming electric field in the cable. However, cable shielding materials >35 kV mainly rely on foreign imports in China, which belongs to the technical weak issues in the field of electrical materials. At present, there are few systematic reports on semiconductive shielding material of HVDC cable. In the work, the mechanisms of charge conduction and thermal conduction of semiconductive material have been introduced. Effect of raw material, carbon black content and the second conductive filler on the resistance characteristics of the semiconductive layer, the charge accumulation characteristics of the insulating layer and the interface characteristics have been studied. A kind of semiconductive layer as a high voltage terminal charge emission method has been proposed to study charge emission from the semiconducting layer to the insulation layer. This work can provide theoretical guidance for the research of semiconductive shielding materials.
Analgesie, Agitation und Delir-Management auf deutschen Intensivstationen
Authors: Hermes Carsten , Zoremba Norbert , Gutschow Markus M. , Hansen Hans-Christian , von Haken Rebecca , Engl Karin , Kindgen-Milles Detlef 
Published: November 2019

ZusammenfassungFür ein erfolgreiches PAD-Management ist eine validierte Erfassung von Schmerz, Agitation und Delir erforderlich. Eine Implementierung erfolgt allerdings nur schleppend. Warum das schneller gehen sollte und was dazu nötig ist, hat ein interaktives Kasuistik-Forum ergeben, bei dem Ärzte und Pflegende gleichermaßen vertreten waren.
Das fiebernde Kind in der pädiatrischen Notaufnahme
Authors: Kranz Gesche 
Published: November 2019

ZusammenfassungWenn ein Kind in die Notaufnahme kommt, ist der häufigste Grund dafür Fieber. Für die erhöhte Körpertemperatur können viele Faktoren verantwortlich sein. In der Ersteinschätzung gilt es, Kinder mit besonderem Behandlungsbedarf zu identifizieren – eine große Herausforderung für die Pflege.
Mit Patientenmanagern die Anschlussversorgung sicherstellen
Authors: Schirbach Dominik , Supprian Claudia 
Published: November 2019

ZusammenfassungPatienten werden auch von der Intensivstation aus entlassen. Mindestens aber wird der Entlassungsprozess dort mit der Aufnahme begonnen. Den Herausforderungen, die sich aus dem Organisationsprozess des Entlassmanagements ergeben, nehmen sich an der Charité – Universitätsmedizin Berlin die Patientenmanager an.
Das I-PACE Modell zur Beschreibung der Entstehung und Aufrechterhaltung von internetbezogenen Störungen und anderen Verhaltenssüchten
Authors: Antons Stephanie , Brand Matthias 
Published: November 2019

ZusammenfassungDas Interaction of Person-Affect-Cognition-Execution Modell fasst, basierend auf der aktuellen Empirie und theoretischen Annahmen, die potentiellen Mechanismen zusammen, die zur Entwicklung und Aufrechterhaltung verschiedener internetbezogener Störungen und anderen Verhaltenssüchten beitragen. Zentrale Annahme des Modells ist, dass Effekte prädisponierender Merkmale einer Person in Interaktion mit affektiven und kognitiven Prozessen und in Interaktion mit Umweltvariablen bzw. mit digitalen Medien die Entwicklung einer spezifischen Verhaltenssucht begünstigen. Zu den affektiven und kognitiven Prozessen zählen Mechanismen der Reizreaktivität und Craving sowie eine Reduktion der Inhibitionskontrolle, welche vermutlich durch neurale Veränderungen in der Suchtentwicklung begünstigt werden. Wenngleich eine Gesamtprüfung des Modells für verschiedene internetbezogene Störungen und andere Verhaltenssüchte noch aussteht, ermöglicht es dennoch die Ableitung von Vorschlägen für die klinische Praxis.
Novel Aspects of White Adipose Tissue Browning by Thyroid
Hormones
Authors: Krause Kerstin 
Published: November 2019

AbstractThyroid hormones are essential for the full thermogenic capacity of brown adipose
tissue. The thermogenic response of brown adipocytes to thyroid hormones is
resulting from the synergistic interaction of thyroid hormones with the
sympathetic nervous system. In recent years, evidence has been provided that
thyroid hormones also induce the browning of white adipose tissues. This review
will provide a brief overview about the recent findings regarding the effects of
thyroid hormones on adipose tissue thermogenesis including central and
peripheral regulation of white adipose tissue browning.
Bioinspired Synthesis and Physical-Chemical Properties of a New 10-Methylpyrano-4′-hydroxyflavylium Chloride Salt
Authors: Cruz Luís , Gomes Vânia , Guimarães Marta , Gonçalves Gabriela , de Freitas Victor 
Published: November 2019

A novel bioinspired 10-methylpyranoflavylium dye was synthesized. The dye was fully characterized by LC-DAD/ESI-MS and NMR 1D and 2D techniques, and its equilibrium constants towards pH variations were determined by UV–vis titration. These studies revealed the presence of three species (a flavylium cation AH+, a neutral quinoidal base A, and an anionic quinoidal base A–) in the pH range 1–12, driven by the two pK a values of the dye: pK a1 = 6.8 ± 0.1 and pK a2 = 10.8 ± 0.1. The first deprotonation of the dye occurs within the pH range for spoilage of many packed-food products, making the dye an excellent candidate for use as a pH sensor for real-time monitoring of the quality and freshness of foods.
Myomectomy for Multiple or Giant Uterine Fibroids
Authors: Hiramatsu Yuji 
Published: November 2019

AbstractMyomectomy for diffuse leiomyomatosis and giant fibroid exceeding 30 cm in length is a particularly difficult operation. For diffuse leiomyomatosis, what kind of incision is put in and nucleated, how to suture the wound is a problem. In the case of giant fibroids, the degree of difficulty varies greatly depending on the site, size, and number of fibroid. The points should be taken into account at the time of surgery are as follows: (1) how to incision because incision becomes long, (2) how to remove multiple fibroids together, reduce incisional wounds, and reconstruct the uterus, (3) how to reduce the bleeding, how to suture not to leave a dead space. From the preoperative magnetic resonance imaging findings for each case, we will conduct surgery as far as possible to simulate, but, in fact, it is necessary to judge instantaneously at the time of laparotomy. It is necessary to see many difficult operations and acquire the judgment ability.
Anthropometric and Metabolic Responses in FTO rs9939609 Gene Polymorphism after a Multidisciplinary Lifestyle Intervention in Overweight and Obese Adolescents
Authors: Barbian Cláudia Daniela , Reuter Cézane Priscila , Renner Jane Dagmar Pollo , da Silva Priscila Tatiana , Klinger Elisa Inês , Hobkirk James Philip , de Moura Valim Andréia Rosane , Burgos Miria Suzana 
Published: November 2019

AbstractFew studies show the potential changing effect of fat-mass and obesity-associated (FTO) rs9939609 gene on cardiometabolic risk after a lifestyle intervention. This study aims to evaluate whether overweight and obese adolescents, carriers of the risk genotypes for obesity of the FTO rs9939609 gene polymorphism, have different anthropometric and biochemical responses to an interdisciplinary intervention program. The quasi-experimental study involved 34 adolescents aged 10 to 15 years. Schoolchildren with AA/AT genotype decreased glucose, total cholesterol, low-density lipoprotein cholesterol, and increased high-density lipoprotein cholesterol. However, there were no differences between the genotypes, suggesting that the “A” allele did not modify the subject's response to the intervention program.
Unilateral Hearing Loss Due to Cochlear Nerve Involvement as Isolated Symptom of a Primary Medulloblastoma
Authors: Magg Janine , Nägele Thomas , Alber Michael , Weichselbaum Annette , Ebinger Martin , Schuhmann Martin U. 
Published: November 2019

AbstractUnilateral sensorineural hearing loss is a common symptom of vestibular schwannomas in adolescent patients with neurofibromatosis type 2 or sporadic vestibular schwannomas and is often the initial clinical feature. While rare cases of sensorineural impairment presenting as vision or hearing loss due to metastatic medulloblastoma are known, hearing loss as an isolated presenting symptom of primary malignant neuroepithelial tumors of the central nervous system has not been reported in the pediatric population so far. We present two adolescents with unilateral hearing loss due to cochlear nerve dysfunction as the only symptom of a primary nonmetastatic medulloblastoma of the WNT signaling pathway family members subgroup.
The necessity modalshave to,must,need to, andshould
Authors: Cappelle Bert , Depraetere Ilse , Lesuisse Mégane 
Published: November 2019

AbstractWhen an ambiguous lexical item appears within a familiar string of words, it can instantly receive an appropriate interpretation from this context, thus being saturated by it. Such a context may also short-circuit illocutionary and other pragmatic aspects of interpretation. We here extract from the British National Corpus over 500 internally highly collocating and high-frequency lexical n-grams up to 5 words containinghave to,must,need to, and/orshould. These contexts-as-constructions go some way toward allowing us to group these four necessity modals into clusters with similar semantic and pragmatic properties and to determine which of them is semantico-pragmatically most unlike the others. It appears thathave toandneed tocluster most closely together thanks to their shared environments (e.g.,you may have/need to…, expressing contingent, mitigated necessity), whileshouldhas the largest share of unique n-grams (e.g., rhetoricalWhy shouldn’t I…?, used as a defiant self-exhortation).
Coercion
Authors: Leclercq Benoît 
Published: November 2019

AbstractThe goal of this paper is to investigate the possibility of a cross-theoretical understanding ofcoercion, a “kind of contextual enrichment/adjustment” (Lauwers & Willems 2011: 1220), by combining insights from Construction Grammar and Relevance Theory. In Construction Grammar, coercion has mostly been discussed in terms of the semantics of the linguistic items that occur in the sentence and how these interact with each other. Relevance Theory, on the other hand, does not distinguish cases of coercion from other instances of lexical adjustment, and discusses them in terms of the pragmatic principles involved during utterance interpretation. In order to highlight the complementarity of the two perspectives, this paper particularly consists in pinning down their respective explanatory limits. It will be shown that coercion is better described in terms of a linguistically required pragmatic process. Therefore, it will be suggested that coercion might actually instantiate a particular type ofsaturation.
Non-exhaustive lists in spoken language
Authors: Mauri Caterina , Goria Eugenio , Fiorentini Ilaria 
Published: November 2019

AbstractThe aim of this paper is to analyze how speakers refer to non-exhaustive sets in spoken discourse, by means of open lists. We will propose an analysis of non-exhaustivity in terms of indexicality and we will therefore consider open lists as having an inherently pragmatic component. Based on corpus data of spoken Italian, we will identify three main types of non-exhaustive lists, showing different structural properties and non-compositional semantics. In order to account for the observed variation, we will take a construction grammatical perspective, arguing that what may appear as a heterogeneous set of strategies is instead an inheritance-based network of constructions sharing a schematic core (cf.Goldberg 1995). We will elaborate on the most recent approaches to list constructions, along the lines proposed byMasini, Mauri, & Pietrandrea (2018), and will identify three types of non-exhaustive list constructions, which inherit the core properties from the upper-level list construction, but at the same time show more specific features and constraints.
Mandatory use of Prescription Drug Monitoring Program and Benzodiazepine Prescribing among U.S. Medicaid Enrollees
Authors: Liang Di , Guo Huiying , Shi Yuyan 
Published: November 2019

Background In the past two decades, the U.S. saw an alarmingly increasing trend of benzodiazepine prescribing. Mandatory use of Prescription Drug Monitoring Programs (PDMPs) was suggested to have the potential to reduce opioid prescribing, but little is known about its impacts on benzodiazepines. This study examined whether PDMP data use mandates were associated with changes in benzodiazepine prescribing in the U.S. Methods Aggregate state quarterly prescription drug records of benzodiazepines for Medicaid enrollees during 2010–2017 were obtained from the U.S. Medicaid State Drug Utilization Data. Three population-adjusted outcome variables were evaluated, including quantity, dosage, and Medicaid spending of benzodiazepine prescriptions per quarter per 100 Medicaid enrollees. The primary policy variable was the state-wide implementation of PDMP data use mandates for benzodiazepines. To account for between-state variations in mandates, an additional policy variable was considered to indicate strong mandates on PDMP data use, which required all prescribers to query a patient's PDMP records for first prescribing and subsequent prescribing at least every 12 months. Linear regressions with difference-in-difference approach were used to assess the associations between PDMP data use mandates and benzodiazepine prescribing, controlling for state-level time-varying policy and socioeconomic covariates. Results The state-wide implementation of PDMP data use mandates for benzodiazepines was not associated with quantity, dosage, or Medicaid spending of benzodiazepine prescriptions. Strong mandates on PDMP data use were not associated with any benzodiazepine prescribing outcomes, either. Conclusions There was no evidence for the associations between PDMP data use mandates for benzodiazepines and changes in benzodiazepine prescribing among Medicaid enrollees. Future research is warranted to replicate the study in other populations using individual patient records and continuously monitor the trends in benzodiazepine prescribing in association with PDMPs.
In situ monitoring of artificial aging and solution heat treatment of a commercial Al–Mg–Si alloy with a high intensity positron beam
Authors: Resch L , Gigl T , Klinser G , Hugenschmidt C , Sprengel W , Würschum R 
Published: November 2019

Abstract
Microstructural changes of a commercial Al–Mg–Si alloy were studied during artificial aging by in situ Doppler broadening spectroscopy using a high-intensity positron beam. The in situ positron annihilation characteristics at high temperatures differ considerably from the conventionally applied ex situ measurements at low temperatures. Therefore, a more comprehensive view of precipitation processes in Al–Mg–Si alloys is obtained. Further, in situ positron–electron annihilation techniques allow for an investigation of aging processes with increased sensitivity. For the artificial aging temperatures of 180 °C and 210 °C pronounced variations of the Doppler broadening S-parameter reveal (i) the evolution of clusters into larger precipitates and (ii) the time of the formation of

” precipitates and the role of vacancies in connection to this. Towards higher aging times, the transformation from coherent

” to semi-coherent

’ precipitates could be verified. Additional insights are gained by in situ measurements of the S-parameter during the solution heat treatment of the previously overaged sample. Here, the S-parameter reveals both the dissolution of precipitates starting from temperatures of 364 °C and the thermal generation of vacancies.