bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in Attitudes toward Nutrition after an Education Program in Polish Teenagers: Report from the ABC of Healthy Eating Study
Authors: Hamulka Jadwiga , Wadolowska Lidia , Kowalkowska Joanna , Jeruszka-Bielak Marta , Frackiewicz Joanna , Gutkowska Krystyna 
Published: June 2020

AbstractThe sustainability of education focused on improving teenagers’ attitudes toward nutrition from a longer-term perspective has not yet been studied extensively. The aim of this study was to determine the sustainability of attitudes toward nutrition after 3 and 9 months among Polish teenagers in a follow-up study. An education-based intervention study was carried out among 464 Polish teenagers aged 11–12 years (educated/control group: 319/145). In the educated group, a multicomponent, school-based education program lasting three weeks and covering five diet-related and lifestyle-related topics was implemented. Attitudes toward nutrition were determined with a shorter version (TFEQ10; 10 statements) of a three-factor eating questionnaire (TFEQ13) dedicated to school-aged adolescents, where three subscales were developed: Emotional Eating (EE: 2 statements, 0–6 points), Uncontrolled Eating (UE: 5 statements, 0–15 points), and Cognitive Restraint of Eating (CRE: 3 statements, 0–9 points). The data was collected 3 times: (i) before education (at baseline), (ii) after 3 months to measure the short-term effect of education, (iii) after 9 months to measure the medium-term effect of education. Differences between groups (educated vs. control or baseline vs. follow-up) were verified with the Mann–Whitney test. At the baseline, the mean values for all three scales were not significantly different between educated and control groups, calculated separately for boys and girls as well as for normal or overweight/obese teenagers, with the exception for Emotional Eating in the total sample and normal weight students. After 3-month follow-up, the mean values decreased in an educated group for all three subscales, for the total sample (EE: 1.3 vs 1.2; UE: 5.2 vs 4.7; CRE: 4.2 vs 4.0), for both sexes, and both body weight subpopulations, while increased or remained on the same level in control group (for total sample EE: 1.5 vs 1.6; UE: 5.6 vs 5.8; CRE: 4.1 vs 4.2). After 9 months, in the educated group, the means slightly increased when compared to the means after 3 months, but were still lower than those at the baseline. This study has shown that nutritional education of teenagers 11–12 years gives a long-lasting effect of attitudes toward nutrition (Emotional Eating and Uncontrolled Eating) visible after 3 months, and to a less extent after 9 months. We suppose, that improvement of the attitudes toward nutrition in teenagers, education programs should be regularly conducted and addressed not only to children but also to the adults responsible for children's nutrition.
The association between perceived stress and diet quality in women of childbearing age: A systematic review
Authors: Khaled Karim , Hundley Vanora , Tsofliou Fotini 
Published: June 2020

AbstractPoor diet quality is a major cause of maternal obesity and associated with adverse metabolic effects for mother and offspring. Psychological stress can increase intake of unhealthy dietary choices (e.g. highly palatable, energy dense diet), but no study has investigated the association between stress and diet quality in women of childbearing age.This systematic review of the association between psychological stress and diet quality used the PEO (Population, Exposure, and Outcome) model.Medline, CINAHL, Scopus, Cochrane Library, Web of Science, and Sciencedirect were searched (October 2018 - January 2019). From 139,552 hits, 471 papers were screened, but only 8 studies met our inclusion criteria: English language, stress (exposure) measured in combination with diet quality (outcome), healthy women (18–49 years of age (population). Data extraction was determined by the PEO. Quality assessment used CASP tool for Cohort studies.The review included eight studies from USA (n = 6), Egypt (n = 1), and Iran (n = 1). The six cross-sectional and two longitudinal studies were published between 2011 and 2017 and had a total of 3,982 participants. Studies were heterogeneous in methods: three used food frequency questionnaires to assess dietary intake while the others used 24-hour dietary recalls. Diet quality was measured using different indices: Alternate Healthy Eating Index (n = 2), Healthy Eating Index (n = 2), Dietary Approach to Stop Hypertension (DASH) Diet Index (n = 2), Dietary Quality Index- Pregnancy (n = 2), and Dietary Guideline Adherence Index (n = 1). Only one study used three diet quality indices. No study explored dietary patterns using factor analysis and other statistical techniques. Most studies used the perceived stress scale to measure stress; however, there were differences regarding the use of this scale to form a continuous or categorical variable (with varying cut-off scores) perceived stress, whereas no study reported biological response to stress. Outcomes also varied in direction of association; no association (n = 4), negative association (n = 3), mixed results (n = 1).This review is the first to systematically examine association between stress and diet quality in women of childbearing age; there was heterogeneity in measures of diet quality and study designs. Future studies that explore diet quality/patterns should include both diet indices and factor analysis and additionally measure biological markers of both dietary intake and stress.
Very high prevalence of vitamin D deficiency in South Asian adults (n 6433) in the UK Biobank: urgent action required
Authors: Darling Andrea , Blackbourn David , Ahmadi Kourosh , Lanham-New Susan 
Published: June 2020

AbstractPublished studies have suggested a high prevalence of 25-hydroxyvitamin D (25OHD) deficiency in western dwelling South Asians, particularly in women. However, sample sizes have been relatively small with few men. Moreover, South Asians are vastly under-represented in national dietary surveys and further research into 25(OH)D status is needed. The UK Biobank is a cohort of 500,000 individuals; n 6433 are of South Asian ethnicity and have baseline serum 25(OH)D data (2006–2010, aged 40–69 years). Blood draws were spread across the year. Of note, the 25(OH)D measurements were produced using the DiaSorin Liaison XL assay which underestimates 25(OH)D by 4% at 25nmol/L, but overestimates 25(OH)D by 5–10% at ≥ 40nmol/\L(1). We used the commonly used cut-points of < 25nmol/L (deficiency), < 50nmol/L (insufficiency). In women (n 2927), median (IQR) was 24.3 (20.5) nmol/L with 50.4% < 25nmol/L, and 88.6% < 50nmol/L. In men (n 3506), median (IQR) was 21.7 (16.2) with 58.4% < 25 nmol/L and 93.8% < 50 nmol/L. Of concern, 17.8% of women and 21.1% of men had 25(OH)D < 15nmol/L. A Mann Whitney test showed that gender differences were statistically significant (P < 0.0001). In terms of ethnic sub-groups, in the Bangladeshi group (n 207), median (IQR) was 26.1 (14.3) nmol/L with 43.5% < 25nmol/L and 91.3% < 50nmol/L. In the Indian group (n 4792), median (IQR) was 23.8 (19.3) with 52.0% < 25nmol/L and 90.4% < 50nmol/L. Finally, in the Pakistani group (n 1434) median (IQR) was 19.3(14.5) with 65.7% < 25nmol/L and 94.9% < 50nmol/L. A Kruskal Wallis test showed that ethnic subgroup differences were statistically significant (P < 0.0001). To the authors’ knowledge, this is the largest analysis to date of 25(OH)D status in European dwelling South Asians. Deficiency of 25(OH)D was almost universal, with 50% or more not even reaching 25nmol/L. Of great concern, 20% of participants had levels < 15nmol/L which, although not a widely used cut-off point, still represents severe deficiency and likely osteomalacia. Moreover, these results are most probably an underestimation of this societal challenge as the UK Biobank is likely to contain participants that are healthier and more educated than the general population. In conclusion, our analyses suggest the need for urgent public health interventions to prevent and treat vitamin D deficiency in UK South Asians. This research was conducted using the UK Biobank Resource under application number 15168.
Consumption and Preferences of Fruits and Vegetables in Turkish Adults
Authors: Güldemir Hilal Hizli , Yousefirad Neda , Akman Cansu , Sezer Fatma Elif , Ilktac Havvanur Yoldas , Garipagaoglu Muazzez , Ersoy Gulgun 
Published: June 2020

AbstractHigh fruit and vegetable intake is associated with reduced risk of future chronic diseases. This study aimed to evaluate the consumption of fruits and vegetables in adults living in Turkey.The study was performed with selected by random sampling method on total of 7693 individuals, who lives in different geographical regions in Turkey. The research data were obtained through a questionnaire applied in face-to-face interview method in June-September 2017. In the study the consumption status, preferences and daily amount of vegetables and fruits were questioned; height, body weight and Body Mass Index (BMI) were evaluated. Statistical analyzes were performed with SPSS 22.0 program.33.2% of the participants were male; 66.8% are female. The mean age of the subjects was 34.8 ± 13.2 years and BMI was 25.3 ± 5.0 kg / m2. According to the World Health Organization, 5.1% of individuals were lean, 46.7% were normal, 30.9% were slightly obese and 17.2% were obese. 95.5% of individuals reported that they consume vegetables and 96.5% of them consume fruits. In vegetable consumption preferences, it was determined that 62.9% of the individuals consumed raw vegetables every day, 80.4% of cooked with meat dishes, 85.0% of cooked meatless dishes, and 59.0% of them consumed as roasted at least once a week. Boiled and steamed vegetables are preferred rarely. In fruit consumption preferences, it was found that 58.7% of the individuals consumed fresh fruits every day, 40.9% of dried fruit, 17.0% of compote and 28.0% of fruit juice at least once a week. BMI was found to be significantly higher in individuals who did not consume vegetables and fruits (p < 0.05).Although the majority of the individuals reported that they consumed vegetables and fruits in general, the BMI of 48.1% was above normal. Informative studies are needed to increase the amount and variety of consumption of vegetables and fruits in Turkish adults.
Role the awareness of healthy nutrition and lifestyle for improving dietary behavior and the bodily status of employees agri-food industry
Authors: Derouiche Abdelfettah , Makhlouki Houria , Elrbaoui Maria , Elkardi Younes , Jafri Ali , Martin Chloé 
Published: June 2020

AbstractIntroduction:Awareness and education Nutritional contribute to the voluntary improvement of dietary behaviour and adopting healthy lifestyle. In a work environment, nutrition education falls under the social responsibility of the employer to promote healthier dietary choices. This study aims to assess the impact of nutrition education on dietary behaviour, lifestyle and body composition on a group of industry workers.Materials and Methods:A group of 44 workers have volunteered to participate to this 6 months’ trial. Participants were aged between 28 and 58 years old (43% women and 57% men). All participants have completed a cap-score questionnaire at the beginning and end of the study, the questionnaire was organised into 3 sections: food groups, dietary behaviour, and lifestyle. Anthropometric measurements (height, weight, BMI, muscle mass, fat mass, hip circumference and waist circumference) were monitored during the study. Nutrition education sessions addressed 4 topics including healthy lifestyle. Participants were free to attend to any of the workshops.Results:Only fifteen participants attended all sessions. Data showed that obesity lowered by 28.6% and overweight increased by 32.6%, body composition changes were not significant. Changes in dietary behaviour were not significant, while scores of food groups and lifestyle changed significantly (p = 0.053 and p = 0.042 respectively).Discussion:This study reveals the commitment of workers to nutrition education which could be a part in improving their dietary choices, their health and their productivity.
Irish children's food and beverage portion sizes: a qualitative study of parents’ views and practices
Authors: Moore Sarah , Kairey Lana , Sikar Karen Matvienko , Kearney Patricia , Kelly Colette , Woodside Jayne , McKinley Michelle , Harrington Janas 
Published: June 2020

AbstractFood portion sizes routinely consumed by children have increased over time and consumption of larger portion sizes is associated with higher weight status. Parents often have the critical role of deciding portion sizes of foods to serve their children. It is not well understood, however, how parents decide the amount of food to serve. This research aimed to investigate parental views on portion sizes of foods and beverages served to children.A purposive sample of preschools and primary schools geographically located in either urban or rural areas of Northern Ireland and the Republic of Ireland, and classified as either high or low deprivation were recruited. Selected schools were invited to facilitate this research. Parents with at least one child aged 2–12 years attending a recruited school were then invited to participate in a focus group. A maximum of three groups were scheduled with interested parents at each school. One researcher moderated the focus groups, assisted by another researcher in all groups where possible. A semi-structured discussion guide was followed, using probes to stimulate discussion. The guide explored practices in portioning foods and beverages for children, factors influencing portioning and views on portion sizes of foods and beverages served to children. Discussions were audio-recorded, transcribed verbatim and data was analysed thematically. Nvivo software was used to manage the coded data.Focus groups (n = 24) ranging in size from 3–12 parents were conducted across 19 schools. The response rate from parents at recruited schools ranged from 1–16%. A total of 144 parents (86% female, mean age 46y) participated, of which 60% had a child attending a high deprivation school and 64% had a child attending a rural school. Factors influencing parental portioning included seven themes comprised of sub-themes: parent knowledge (portion size knowledge, serving a learned amount), parent motivations (ensure child is fed, encourage healthier food), child-related factors (appetite, body size, food preferences, eating patterns), family influence (spouses and grandparents serving), food retail and other settings (restaurants, takeaways, special occasions), socio-cultural influences (parent childhood experiences, parents’ portion size norms) and portioning resources used (serve ware, utensils, hand sizes).Parents’ main concern regarding the amount they feed their children was to ensure that they are fed a sufficient amount to feel full. Parents learned this amount through experience and felt it was specific to each child's appetite. These findings will inform future interventions and information campaigns to help parents understand child portion sizes.
Differential Effects of Lipid and Vitamin D treatment on Cell Viability and CYP24A1 Expression in Hepatocytes and Hepatic Stellate Cells
Authors: Zhang Zixuan , Thorne James L. , Moore J. Bernadette 
Published: June 2020

AbstractActivated hepatic stellate cells (HSCs) are a key contributor to liver fibrosis and drive the progression to advanced disease for many liver conditions, including non-alcoholic fatty liver disease. Previous studies suggest vitamin D may reduce inflammatory and pro-fibrogenic activity of HSCs in vitro. However, the mechanisms underpinning the effects of vitamin D in HSCs are not fully understood. The overall aim of these experiments was to mimic a lipid loading model on immortalised HSCs to test their responses to 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). Two different human immortalised cell lines: HepG2, hepatocellular carcinoma cells, and LX-2, hepatic stellate cells; were cultured using standard methods. Cell viability in different treatment vehicles (2% DMSO and/or 0.1% ethanol) under serum free conditions was measured by MTT assay after 6 and 24 h. Cells were cultured with increasing concentrations of fatty acids (0–500μM, 1:1 oleic acid: palmitic acid) or vitamin D. Nile red, a neutral lipophilic fluorescent dye, was used to measure total intracellular lipid and quantified relative to vehicle. CYP24A1 mRNA expression was measured by qPCR in response to 1000nM 1α,25(OH)2D3 treatment in both cell lines for 24 h using TaqMan® gene expression assays and normalised to 18S rRNA. Cell viability in response to vehicle was examined at 6 h and 24 h to determine the optimal experimental time points. Whereas, HepG2 cells remained unaffected at 24 h in response to either or both vehicles combined (n = 4; combined vehicles, P = 0.3187), LX-2 cells showed reduced viability even at 6 h (n = 5; combined vehicles, P = 0.0050). Fatty acid treatment led to intracellular lipid accumulation in both cell lines. In response to 500μM fatty acid treatment, intracellular lipid increased by 1.7-fold in LX-2 cells at 6 h (n = 5, P = 0.00174) and 3.9-fold in HepG2 cells after 24 h (n = 4, P = 0.00184). Notably, CYP24A1 mRNA expression was markedly induced by vitamin D treatment in LX-2 cells (136 ± 7.64-fold, n = 3, P = 0.0010) in comparison to HepG2 cells (22 ± 0.78-fold, n = 3, P < 0.0001). In summary, the cell viability data suggested optimal time points for both fatty acid and vitamin D treatments may be 6 h for LX-2 cells, and 24 h for HepG2 cells. While intracellular lipid accumulation differed between the cell lines in response to fatty acid treatment, both cell lines produced a dose-dependent increase in intracellular lipid. Lastly, CYP24A1 mRNA expression confirmed the responsiveness of both cell types to vitamin D treatment. Ongoing experiments are examining microRNA expression in HSCs in response to both vitamin D and lipid loading.
Dose-response study of the effect of a nutraceutical combining oat beta-glucan and green coffee hydroxycinnamates in overweight/obese subjects
Authors: Mateos Raquel , Garcia-Cordero Joaquin , Gonzalez-Ramila Susana , Sarria Beatriz , Bravo Laura 
Published: June 2020

AbstractObesity and its associated comorbidities (type 2 diabetes mellitus, cardiovascular disease, etc.) are a major public health concern worldwide, with prevalence of obesity affecting in Europe up to 17% of the adult population (OCED/EU 2016). Strategies to lose weight mostly relay in lifestyle changes such as restriction in food intake and increased exercise. However, these are not always easily accepted by overweight/obese subjects and their long-term efficiency is limited. Nutraceuticals and functional foods might be an alternative means to help lose weight and reduce associated cardiometabolic risk factors in affected subjects. There are different nutraceuticals/functional foods containing dietary fibre (DF) or polyphenol-rich plant extracts, but to our knowledge there is no nutraceutical combining both bioactive compounds.The objective of the present study was to assess the efficiency on different risk makers of a dietary supplement combining a soluble DF (oat beta-glucan -BG-) and a green coffee bean extract (GCBE) rich in polyphenols (PP) in overweight/obese subject.A randomized, parallel, blind, dose-response study was performed in 60 overweight/obese subjects divided into four groups (n = 15) who consumed during 6 weeks two servings per day of one of four nutraceutical formulations containing low (3 g/d) or high (5 g/d) doses of BG of different purity (35 & 70%) and a fixed amount of GCBE providing 600 mg/d PP. Food intake, anthropometry and different cardiometabolic markers were assessed at the beginning and end of the intervention.Results showed reduced levels of total cholesterol (p = 0.0001), LDL-cholesterol (p = 0.01), VLDL-cholesterol (p = 0.014) and triglycerides (p = 0.023). There were differences among both types of BG, with the 35% BG being more effective reducing lipid plasma levels than the 70% BG. Percentage of body fat significantly decreased after the intervention, the 70% BG being more efficient than the 35% BG. However, there was no effect on body weight and body mass index, which were not significantly modifiedIt can be concluded that DF and PP might have a synergistic effect reducing cardiometabolic risk factors in overweight/obese subjects.Funded by Spanish State Research Agency, project AGL2015-69986-R
Heart rate variability and long chain n-3 PUFA in patients with chronic kidney disease commencing haemodialysis: a cross-sectional study
Authors: Pinto Ana , MacLaughlin Helen , Gray Robert , Hall Wendy 
Published: June 2020

AbstractThe risk of sudden cardiac death (SCD) is doubled when a patient with chronic kidney disease (CKD) stage 5 starts haemodialysis. Low heart rate variability (HRV) has been reported to be independently associated with increased risk of SCD and all cardiac death in haemodialysis patients. Long chain n-3 polyunsaturated fatty acids (LC n-3 PUFA; 20:5n-3, EPA and 22:6n-3, DHA) may exert anti-arrhythmic effects on cardiac myocytes. Haemodialysis patients have lower serum LC n-3 PUFA levels compared to populations without CKD. Few studies have investigated the relationship between LC n-3 PUFA and HRV in patients with CKD. This study aimed to characterise the variability of LC n-3 PUFA status in patients who recently commenced haemodialysis, and to investigate relationships between LC n-3 PUFA status and HRV. A cross-sectional study was conducted in adults aged 40–80 years with CKD commencing haemodialysis (within 6–10 weeks) (NRES research ethics committee ref: 14/LO/0186). At 2 separate study days, pre-dialysis blood samples were taken to measure fatty acid composition by GC, and HRV monitors (Actiheart, CamNtech Ltd, UK) were fitted after dialysis had started to monitor parameters of cardiac autonomic function during dialysis, during the night, and for a total of 24 h. Forty-five patients (mean age 58 y, SD 9, 20 females/25 males) completed data collection at least once; 91% presented hypertension and 39% had type 2 diabetes. Sample mean omega-3 index (O3I; EPA + DHA as a % of fatty acids in erythrocyte membranes) was very low (3.45%, SD 1.25; median 3.26 %, IQR 1.32); only 2 individuals had O3I > 5%. Variability in erythrocyte EPA (median 0.66 %, IQR 0.42) and DHA (median 2.40 %, IQR 1.32) was limited. Most HRV parameters did not significantly correlate with O3I following adjustment (e.g. age, BMI, β-blockers). Plasma EPA significantly positively correlated with overall and longer phase components of HRV and significantly negatively correlated with beat-to-beat variability over 24 h after full adjustment for confounders. This suggests that although higher circulating EPA concentrations were associated with better cardiac responsivity to environmental stimulations over 24 h, they were also associated with poorer parasympathetic tone (the predominant influence on beat-to-beat HRV). No correlations were observed between plasma DHA and HRV. The divergent pattern of relationships between plasma EPA versus DHA and HRV raises the theory that patients commencing haemodialysis may have compromised conversion of EPA to DHA which may impair vagally-mediated regulation of cardiac autonomic function, a potential mechanism for high risk of SCD.