bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advanced Curation of Astromaterials for Planetary Science
Authors: McCubbin Francis M. , Herd Christopher D. K. , Yada Toru , Hutzler Aurore , Calaway Michael J. , Allton Judith H. , Corrigan Cari M. , Fries Marc D. , Harrington Andrea D. , McCoy Timothy J. , Mitchell Julie L. , Regberg Aaron B. , Righter Kevin , Snead Christopher J. , Tait Kimberly T. , Zolensky Michael E. , Zeigler Ryan A. 
Published: November 2019

AbstractJust as geological samples from Earth record the natural history of our planet, astromaterials hold the natural history of our solar system and beyond. Astromaterials acquisition and curation practices have direct consequences on the contamination levels of astromaterials and hence the types of questions that can be answered about our solar system and the degree of precision that can be expected of those answers. Advanced curation was developed as a cross-disciplinary field to improve curation and acquisition practices in existing astromaterials collections and for future sample return activities, including meteorite and cosmic dust samples that are collected on Earth. These goals are accomplished through research and development of new innovative technologies and techniques for sample collection, handling, characterization, analysis, and curation of astromaterials. In this contribution, we discuss five broad topics in advanced curation that are critical to improving sample acquisition and curation practices, including (1) best practices for monitoring and testing of curation infrastructure for inorganic, organic, and biological contamination; (2) requirements for storage, processing, and sample handling capabilities for future sample return missions, along with recent progress in these areas; (3) advancements and improvements in astromaterials acquisition capabilities on Earth (i.e., the collection of meteorites and cosmic dust); (4) the importance of contamination knowledge strategies for maximizing the science returns of sample-return missions; and (5) best practices and emerging capabilities for the basic characterization and preliminary examination of astromaterials. The primary result of advanced curation research is to both reduce and quantify contamination of astromaterials and preserve the scientific integrity of all samples from mission inception to secure delivery of samples to Earth-based laboratories for in-depth scientific analysis. Advanced curation serves as an important science-enabling activity, and the collective lessons learned from previous spacecraft missions and the results of advanced curation research will work in tandem to feed forward into better spacecraft designs and enable more stringent requirements for future sample return missions and Earth-based sample acquisition.
Does time inconsistency differ between gain and loss? An intra-personal comparison using a non-parametric elicitation method
Authors: Shiba Shotaro , Shimizu Kazumi 
Published: November 2019

Abstract
Several studies on time preference have found time inconsistency in both gain and loss preferences. However, the relationship between the two within the same person remains unclear; that is, does an individual who demonstrates time inconsistency for gain outcomes do so for losses as well? This paper reports on individuals’ time inconsistency for gains and losses in a laboratory setting. To obtain a precise comparison of individuals’ time inconsistency for gains and losses, we used Rohde’s “DI (decreasing impatience)-index” (Manag Sci 65(4):1700–1716, 2018) and measured the level of time inconsistency, rather than merely identifying whether TI was present. This index represents how strongly a person exhibits present bias, and easily extends to the comparison between gain and loss preferences within the same person. Further, it allows the experiment to test for so-called future bias, which has been a focus area in recent time inconsistency literature. It is elicited through a non-parametric method, which avoids any specification errors in the analysis. Our findings are as follows: first, we found future bias in preferences for not only gains but also losses, and we confirmed that this tendency is consistent with previous findings on preferences for gains. Second, a positive correlation between time inconsistency for gains and losses was found at the individual level. Indeed, we could not find a significant difference between the two in most cases.
Microstructure and Mechanical Properties of Ti-Nb Alloys Prepared by Mechanical Alloying and Spark Plasma Sintering
Authors: Kalita Damian , Rogal Łukasz , Czeppe Tomasz , Wójcik Anna , Kolano-Burian Aleksandra , Zackiewicz Przemysław , Kania Bogusz , Dutkiewicz Jan 
Published: November 2019

AbstractThe effect of Nb content on microstructure, mechanical properties and superelasticity was studied in Ti-Nb alloys fabricated by powder metallurgy route using mechanical alloying and spark plasma sintering. In the microstructure of the as-sintered materials, undissolved Nb particles as well as precipitations of α-phase at grain boundaries of β-grains were observed. In order to improve the homogeneity of the materials, additional heat treatment at 1250 °C for 24 h was performed. As a result, Nb particles were dissolved in the matrix and the amount of α-phase was reduced to 0.5 vol.%. Yield strength of the as-sintered alloys decreased with Nb content from 949 MPa for Ti-14Nb to 656 MPa for Ti-26Nb, as a result of the decreasing amount of α-phase precipitations. Heat treatment did not have a significant effect on mechanical properties of the alloys. A maximum recoverable strain of 3% was obtained for heat-treated Ti-14Nb, for whichAsandAftemperatures were − 12.4 and 2.2 °C, respectively.
Capsaicin-Induced Impairment of Functional Network Dynamics in Mouse Hippocampus via a TrpV1 Receptor-Independent Pathway: Putative Involvement of Na+/K+-ATPase
Authors: Balleza-Tapia Hugo , Dolz-Gaiton Pablo , Andrade-Talavera Yuniesky , Fisahn André 
Published: November 2019

Abstract
The vanilloid compound capsaicin (Cp) is best known to bind to and activate the transient receptor potential vanilloid receptor-1 (TrpV1). A growing number of studies use capsaicin as a tool to study the role of TrpV1 in the central nervous system (CNS). Although most of capsaicin’s CNS effects have been reported to be mediated by TrpV1 activation, evidence exists that capsaicin can also trigger functional changes in hippocampal activity independently of TrpV1. Recently, we have reported that capsaicin induces impairment in hippocampal gamma oscillations via a TrpV1-independent pathway. Here, we dissect the underlying mechanisms of capsaicin-induced alterations to functional network dynamics. We found that capsaicin induces a reduction in action potential (AP) firing rate and a subsequent loss of synchronicity in pyramidal cell (PC) spiking activity in hippocampus. Moreover, capsaicin induces alterations in PC spike-timing since increased first-spike latency was observed after capsaicin treatment. First-spike latency can be regulated by the voltage-dependent potassium current D (ID) or Na+/K+-ATPase. Selective inhibition of ID via low 4-AP concentration and Na+/K+-ATPase using its blocker ouabain, we found that capsaicin effects on AP spike timing were completely inhibited by ouabain but not with 4-AP. In conclusion, our study shows that capsaicin in a TrpV1-independent manner and possibly involving Na+/K+-ATPase activity can impair cognition-relevant functional network dynamics such as gamma oscillations and provides important data regarding the use of capsaicin as a tool to study TrpV1 function in the CNS.
Neurovascular Unit as a Source of Ischemic Stroke Biomarkers—Limitations of Experimental Studies and Perspectives for Clinical Application
Authors: Steliga Aleksandra , Kowiański Przemysław , Czuba Ewelina , Waśkow Monika , Moryś Janusz , Lietzau Grażyna 
Published: November 2019

AbstractCerebral stroke, which is one of the most frequent causes of mortality and leading cause of disability in developed countries, often leads to devastating and irreversible brain damage. Neurological and neuroradiological diagnosis of stroke, especially in its acute phase, is frequently uncertain or inconclusive. This results in difficulties in identification of patients with poor prognosis or being at high risk for complications. It also makes difficult identification of these stroke patients who could benefit from more aggressive therapies. In contrary to the cardiovascular disease, no single biomarker is available for the ischemic stroke, addressing the abovementioned issues. This justifies the need for identifying of effective diagnostic measures characterized by high specificity and sensitivity. One of the promising avenues in this area is studies on the panels of biomarkers characteristic for processes which occur in different types and phases of ischemic stroke and represent all morphological constituents of the brains’ neurovascular unit (NVU). In this review, we present the current state of knowledge concerning already-used or potentially applicable biomarkers of the ischemic stroke. We also discuss the perspectives for identification of biomarkers representative for different types and phases of the ischemic stroke, as well as for different constituents of NVU, which concentration levels correlate with extent of brain damage and patients’ neurological status. Finally, a critical analysis of perspectives on further improvement of the ischemic stroke diagnosis is presented.
JMJD3 in the regulation of human diseases
Authors: Zhang Xiangxian , Liu Li , Yuan Xia , Wei Yuquan , Wei Xiawei 
Published: November 2019

AbstractIn recent years, many studies have shown that histone methylation plays an important role in maintaining the active and silent state of gene expression in human diseases. The Jumonji domain-containing protein D3 (JMJD3), specifically demethylate di- and trimethyl-lysine 27 on histone H3 (H3K27me2/3), has been widely studied in immune diseases, infectious diseases, cancer, developmental diseases, and aging related diseases. We will focus on the recent advances of JMJD3 function in human diseases, and looks ahead to the future of JMJD3 gene research in this review.
Effect of Lysyllysine on non-covalent hybridization of single walled carbon nanotube by single-stranded DNA homodimer: in silico approach
Authors: Bagherolhashemi Fateme , Bozorgmehr Mohammad Reza , Momen-Heravi Mohammad 
Published: November 2019

Abstract
In this work, the interactions between adenine–adenine di-nucleotide (DA2N) and carbon nanotube (CNT) in the presence of Lysyllysine (LL) was studied by the molecular dynamics simulation. Different carbon nanotubes including (5.5), (6.6) and (7.7) were used to investigate the effect of CNT type. The binding energies were calculated using the molecular mechanics-Poisson Bolzmann surface area method. The results showed that the contribution of the van der Waals interactions between DA2N and CNT was greater than that of the electrostatic interactions. The LL significantly enhanced the electrostatic interactions between the DA2N and CNT (6.6). The quantum calculations revealed that the sensor properties of the DA2N were not significantly affected by the CNT and LL. However, the five-membered ring of adenine played a more important role in the sensing properties of the DA2N. The obtained results are consistent with the previous experimental observations that can help to understand the molecular mechanism of the interaction of DA2N with CNT.

Graphic abstract
Use of local anesthetic for the resolution of benign anorectal pathology in the Social Security Institute of Guatemala (IGSS)
Authors: Maldonado Hernández Pablo , Ramírez Godoy Laura , Méndez Morán Maxi , San José Gómez Jorge , Cordoba Paíz Juan Pablo 
Published: November 2019

Abstract
Introduction The use of regional anesthetic block has increased, along with the reduction of the use of spine anesthetic in this particular field of surgical activity. In the last decade ambulatory surgery and local anesthetic have lower surgical time, complications of the anesthetic itself, and hospital stay.
Objective Presenting the results obteained with the use of local anesthesic and analgesic in the resolution of benign anorectal pathology.
Methods A prospective, longitudinal, study, from January 2017 to December 2017, patients were classified according to surgical procedures performed using analogical visual scale to determine the pain tolerance, during the procedure, 24 h later and in the 5th post operative day.
Results 253 procedures were performed with 116 local analgesia, 116 were male (45.86%) years 137 female (54%), Milligan-Morgan hemorroidectomy with Ligasure and fistulotomy were the most frequently performed procedures 32% each, followed by biopsy 16%, left lateral esfinterotomy 13% and cutaneous appendix 12%. Females presented better pain tolerance than males patients (92 vs. 81), 68% referred good tolerance through the procedure.
Conclusions 68% of all the patients obtained good pain tolerance through anal anesthetic block, females manifested better pain tolerance than males, in non-complicated anorectal pathology local block ha shown to be safe and reproductible for the treatment of benign anorectal pathology in the Guatemalan Institute for Social Security.
Do SNAP Recipients Get the Best Prices?
Authors: March Raymond J. , Carpio Carlos E. , Boonsaeng Tullaya , Lyford Conrad P. 
Published: November 2019

AbstractWe developed an expensiveness index and used the Food Acquisition and Purchase Survey data set to examine empirically whether Supplemental Nutrition Assistance Program (SNAP) participants pay higher prices compared with nonqualifying and qualifying, but nonparticipating, households. Purchasers’ ability to minimize food expenditures has significant effects on the program’s effectiveness and on participants’ food security. Using ordinary least squares and two techniques that control for the endogeneity of SNAP participation, we found no significant effect of SNAP participation on food prices. Moreover, we found that SNAP participants pay, on average, lower prices than do nonparticipants. We conclude by providing suggestions for policy improvements and implications for future research.
Reforming the Constitution; Reforming the Postcolonial State? Indigenous Peoples and Constitutional Reforms in Taiwan
Authors: VAN BEKHOVEN Jeroen 
Published: November 2019

AbstractWhen an authoritarian state starts democratic transition reforms, the constitution can facilitate such reforms. However, a little-studied role of the constitution during democratic transition is that it can back indigenous peoples’ demands. Constitutional reform during democratic transition enables indigenous peoples to challenge the state's ‘internal colonialism’. The democratic institutions and democratic rights established and guaranteed by the constitution open possibilities for indigenous peoples to push for constitutional reforms that promote ‘internal decolonization’. This means that indigenous peoples are empowered and that their interests are protected. For indigenous peoples, a ‘double transition’ can thus take place: from authoritarianism to democracy, and from internal colonialism to internal decolonization. A case study of the constitutional reforms in Taiwan confirms that the constitution can guarantee indigenous peoples’ participation in constitutional reform. But in Taiwan, this involvement has not led to meaningful incorporation of indigenous peoples in the constitution, and it has not fully promoted double transition. The case study highlights serious problems for indigenous peoples to realize strong constitutional reforms. This article provides a foundation for additional research on constitutional change and indigenous peoples. This is critical to advance constitutional theory and to ascertain whether and how constitutions can give indigenous peoples a voice.
Shifting focus toward healthcare-associated bloodstream infections: The need for neonatal intensive care unit–specific NHSN definitions
Authors: Advani Sonali D. , Murray Thomas S. , Murdzek Christina M. , Aniskiewicz Michael J. , Bizzarro Matthew J. 
Published: November 2019

Abstract

Objective:
Healthcare-associated bloodstream infections (HABSIs) are a significant cause of mortality and morbidity in the neonatal intensive care unit (NICU) population. Our objectives were to review the epidemiology of HABSIs in our NICU and to examine the applicability of National Healthcare Safety Network (NHSN) definitions to the NICU population.

Methods:
We performed a retrospective review of all neonates admitted to the 54-bed, level IV NICU at Yale-New Haven Children’s Hospital with a HABSI between January 1, 2013, and December 31, 2018. Clinical definitions per NICU team and NHSN site-specific definitions used for source identification were compared using the McNemar χ2 test.

Results:
We identified 86 HABSIs with an incidence rate of 0.80 per 1,000 patient days. Only 13% of these were CLABSIs. Both CLABSIs and non–catheter-related bloodstream infections occurred primarily in preterm neonates, but the latter were associated with a significantly higher incidence of comorbidities and the need for respiratory support. The NHSN definitions were less likely to identify a source compared to the clinical definitions agreed upon by our NICU treating team (P < .001). Furthermore, 50% of patients without an identified source of infection by NHSN definitions were bacteremic with a mucosal barrier injury organism, likely from gut translocation.

Conclusions:
HABSIs occur primarily in premature infants with comorbidities, and CLABSIs account for a small proportion of these infections. With the increasing focus on HABSI prevention, there is a need for better NHSN site-specific definitions for the NICU population to prevent misclassification and direct prevention efforts.
Cognitive emotion regulation and personality: an analysis of individual differences in the neural and behavioral correlates of successful reappraisal
Authors: Scheffel Christoph , Diers Kersten , Schönfeld Sabine , Brocke Burkhard , Strobel Alexander , Dörfel Denise 
Published: November 2019

Abstract
A common and mostly effective emotion regulation strategy is reappraisal. During reappraisal, activity in cognitive control brain regions increases and activity in brain regions associated with emotion responding (e.g., the amygdala) diminishes. Immediately after reappraisal, it has been observed that activity in the amygdala increases again, which might reflect a paradoxical aftereffect. While there is extensive empirical evidence for these neural correlates of emotion regulation, only few studies targeted the association with individual differences in personality traits. The aim of this study is to investigate these associations more thoroughly. Seventy-six healthy participants completed measures of broad personality traits (Big Five, Positive and Negative Affect) as well as of more narrow traits (habitual use of emotion regulation) and performed an experimental fMRI reappraisal task. Participants were instructed to either permit their emotions or to detach themselves from the presented negative and neutral pictures. After each picture, a relaxation period was included. Reappraisal success was determined by arousal ratings and activity in the amygdala. During reappraisal, we found activation in the prefrontal cortex and deactivation in the left amygdala. During the relaxation period, an immediate aftereffect was found in occipital regions and marginally in the amygdala. Neither personality traits nor habitual use of emotion regulation predicted reappraisal success or the magnitude of the aftereffect. We replicated typical activation and deactivation patterns during intentional emotion regulation and partially replicated the immediate aftereffect in the amygdala. However, there was no association between personality traits and emotion regulation success.
U–Pb ages of Miocene near-trench granitic rocks of the Southwest Japan arc: implications for magmatism related to hot subduction
Authors: Shinjoe Hironao , Orihashi Yuji , Anma Ryo 
Published: November 2019

AbstractWe present a new dataset of zircon U–Pb ages that document igneous activity in the SW Japan arc during middle Miocene time and discuss its relationship with the opening of the Japan Sea, Philippine Sea plate migration, and subduction of the young hot lithosphere of the Shikoku Basin. Precursory magmatism, characterized by dike and stock intrusions, startedc. 15.6 Ma in both Kyushu and the Kii Peninsula. Most plutonism occurred between 15.5 and 13.5 Ma in an area 600 km long and 150 km wide. No along-arc trend was recognized in the U–Pb ages of igneous activity near the trench. Our data indicate that all near-trench middle Miocene igneous activity occurred immediately after the opening of the Japan Sea ceased, i.e. after 16 Ma, implying that melt extraction and the emplacement of granites in the near-trench region had some influence on the back-arc opening. Our data also imply that the trench–trench–trench-type triple junction between the Japan arc and the Izu–Bonin–Mariana arc must have reached the east side of the Kii Peninsula by 15.6 Ma. The wide distribution of contemporaneous magmatic activity along the arc requires a trench-parallel heat source, such as the subduction of a trench-parallel ridge or a young and highly segmented ridge–fracture zone system in addition to the hot wedge mantle condition related to the opening of Japan Sea.
Emotional Stop Cues Facilitate Inhibitory Control in Schizophrenia
Authors: Zheng Qi , Yang Tian-Xiao , Ye Zheng 
Published: November 2019

AbstractObjective:Inhibitory control is a key deficit in patients with schizophrenia. This study aims to test whether emotions can facilitate inhibition in patients with schizophrenia when they increase attention to inhibitory process.Method:A total of 36 patients with schizophrenia and 36 healthy controls completed an emotional stop-signal task. The task involved selective responses to “Go” stimuli and stopped response when emotional or neutral stop cues occurred.Results:In all conditions, patients with schizophrenia took longer time to inhibit response compared with healthy controls, indicating an overall impairment in response inhibition. Importantly, patients with schizophrenia and controls acquired similar size of benefit from the negative stop cues, showing as reduced reaction time to negative than neutral stop cues. However, the negative stop cues impaired subsequent Go performance only in patients with schizophrenia, indicating additional cost of the negative stop cues for patients with schizophrenia. In both groups, the positive stop cues did not have any significant influence on response inhibition.Conclusions:These findings provide novel evidence for the benefit of emotional stop cues on inhibitory control in patients with schizophrenia and reveal different after-effects of emotional enhancement effect in patients and healthy populations. The findings may help develop effective interventions for improving inhibitory control in patients with schizophrenia and other clinical populations.