bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sensory evaluation and acceptance of food made of edible insects
Authors: Adámek Martin , Adámková Anna , Kouřimská Lenka , Mlček Jiří , Vojáčková Klára , Orsavová Jana , Bučková Martina , Faměra Oldřich , Búran Martin 
Published: October 2020

This paper discusses the sensory analysis of food enriched with selected edible insect species which are labelled as a novel food – house cricket (Acheta domesticus) and mealworm (Tenebrio molitor). Energy bars of two different compositions with the addition of cricket flour and puff pastry bars sprinkled with the whole roasted mealworm larvae were evaluated by consumer tests performed via a questionnaire survey. Respondents represented both men and women in equal numbers and included consumers with the experience of the sensory analysis and edible insects to ensure accurate results. Sensory analyses revealed that respondents associated their tastes with already known flavors (salty, sweet, bitter, fish, French fries, chicken, and mushrooms). The most common answer from respondents was a salty taste, followed by a sweet taste. There were also unusual comparisons such as pine seeds. Consumers’ positive attitude to these energy bars has been registered which shows that the Czech consumer accepts edible insects in a suitable form as a novel food and possible part of the food basket.
Evaluation of dynamic ground characteristics and seismic microzoning
Authors: Kitagawa Yoshikazu , Matsushima Yutaka 
Published: October 2020

The maximum earthquake motions on the ground, the dynamic characteristics of soil-layers in the range of short period reflecting the shallow soil-layers on a small area are investigated, taking Sendai district damaged by the Off-Miyagi Prefecture Earthquake of June, 1978 as an example. The modeling of ground characteristics is performed based on the results of the analytical investigation of the elastic and inelastic system as well as microtremor measurements, boring data and penetration tests.
In order to establish an appropriate seismic microzoning method with particular attention to the mathematical modeling, the predominant periods, magnification factors, maximum accelerations and velocities on the ground surface and the ductility factors of super-structure are computed. The correlation between such seismic microzoning maps and the extent of real damage to buildings is satisfactory.
Smallsteps versus Heiploeg: wat is de stand van zaken?
Authors: van Erpers Roijaards V.M. 
Published: October 2020

Smallsteps versus Heiploeg: wat is de stand van zaken?
Na het Europese Hof in het Smallsteps-arrest heeft de Hoge Raad zich in de Heiploeg-zaak onlangs uitgesproken over de arbeidsrechtelijke gevolgen van een doorstart die is voorbereid middels een pre-pack. Opvallend is dat deze uitspraken uiteenlopen. Daarom legt de auteur in deze bijdrage het Heiploeg-arrest langs de meetlat van het Smallsteps-arrest en beziet zij wat de implicaties van het Heiploeg-arrest zijn.
Dynamics of indexes of reproduction and selection in three generations of the urbanized population
Authors: Kozak N. O. , Atramentova L. A. 
Published: October 2020

Aim. Due to the fact that women's reproductive behavior has been changing with the development of civilization, from natural uncontrolled fertility in the early stages of human development to reproductive technologies in our time, the aim of this work was to study the direction and intensity of natural selection index and changes of the quantitative characteristics of reproduction in women residents of Kharkiv in three successive generations. Methods. Material was collected in 1990 and 2017. The obstetric and gynecological history of the inhabitants of Kharkiv was studied. The first generation included 589 women who were born in 1900–1925, 244 women born in the period 1928–1955, made up the second generation, 288 women who were born in 1956–1979, were assigned to third generation. Results. The total selection index is reduced from 0.56 in the first generation to 0.29 and 0.28 in the second and third generations, respectively. Over the eighty-year period, the differential fertility rate has decreased. The percentage of women with pathological pregnancies increased from 4.9 in the first generation, to 22.5 in the second and 18.4 in the third generation. Conclusions. The total selection index in the Kharkiv population into three successive generations has decreased by half: from 0.56 to 0.28, the index of differential mortality has decreased by almost four times.
Keywords: reproductive characteristics, Kharkov population, Crow's index, selection, generations.
SWS/NTE-dependent neuropathy is the model system to study neurodegeneration
Authors: Matiytsiv N. P. 
Published: October 2020

Today there is many described neurodegenerative D. melanogaster mutants, which characterized by development of degenerative changes in brain. One of them are a swiss cheese (sws) gene mutants. Mutations in this gene causes apoptosis of neurons and hyperwrapping of their somas by the glial cells, reducing of life expectancy and decrease of locomotion. The sws gene is the ortholog of mammal’s neuropathy target esterase (NTE / PNPLA6). NTE is s neuronal, transmembrane protein, that possesses serinesterase activity, and can be the target for neurotoxic organophosphorus compounds activity. Mutations in PNPLA6 gene cause number hereditary neurodegenerative disorders, which nowadays are incurable. The search for therapeutic agents require use of model objects because researches on humans have both methodical and ethical limitations. During two last decades D. melanogaster has proven itself as a good model for study of neurodegenerative diseases. In this review, we described general characteristics of D. melanogaster gene sws, consequences of its mutations and provided evidences of high conservatism of gene product.
Keywords: gene swiss cheese, neuropathy target esterase, neurodegeneration, brain, life span.
γ-tubulin gene intron length polymorphism of Arabidopsis thaliana
Authors: Rabokon A. M. , Bilonozhko Yu. O. , PostovoitovA A. S. , Kalafat L. O. , Pirko Ya. V. , Blume Ya. B. 
Published: October 2020

Aims. Verification of the possibility of using the γ-tubulin gene intron length polymorphism method in genetic studies of plants on the example of Arabidopsis thaliana. Methods. The γ-tubulin gene intron length polymorphism evaluating method was used. Amplified fragments DNA were fractionated by electrophoresis in non-denaturing polyacrylamide gel. DNA bands were detected using silver nitrate staining. Results. Arabidopsis was first time analyzed using the γ-tubulin gene intron length polymorphism method. During amplification with degenerate primers 2 amplicons (520 bp and 555 bp) were formed in all samples. However, using selected arabidopsis-specific primers for the second intron of the γ-tubulin genes, it was possible to find several samples that differ in their DNA profile. Conclusions. It is established that the proposed method can be used in molecular genetic studies of plants. Moreover, the developed specific primers for γ-tubulin gene introns can probably be used both for the study of Arabidopsis and related species. The use of degenerate primers can be useful in the study of plants for which there is no information about their genome.
Keywords: molecular-genetic markers, intron length polymorphism, γ-tubulin, A. thaliana.
The role of rabbit seminal plasma natural antioxidants in the realization of spermatozoid activity after ionizing irradiation
Authors: Klepko A. V. , Kondratova Yu. A. , Gudkov I. M. 
Published: October 2020

Aim. To investigate the effects of X-rays on the content of rabbit seminal plasma L-carnitine and α-tocopherol, as well as physiological parameters of spermatozoid in 10, 30 and 90 days after whole body irradiation of animals in the dose range of 0.1–2.0 Gy. Methods. White rabbits-males Soviet Shinshila were irradiated by X-rays. Physiological parameters of sperm were evaluated by light microscopy, and the content of natural antioxidants was determined using liquid chromatograph “Agilent 1200”. Results. It was shown that low doses of ionizing radiation (0.1 Gy and 0.5 Gy) in 10 days after irradiation lead to the increase of the L-carnitine level in seminal plasma, whereas at 1.0 Gy and 2.0 Gy its concentration decreases. In additional, there is a decrease in the seminal plasma α-tocopherol content with a minimum of 2.0 Gy, although a dose of 0.1 Gy dose not cause changes in the index. The L-carnitine level is no longer different from the control for a dose 0.1 Gy in one month after rabbit irradiation, while the α-tocopherol concentration continues to decrease. Conclusions. The increasing of L-carnitine level in the rabbit’s seminal plasma at 0.1 Gy and 0.5 Gy contributes to increased motility and a radio-stimulating effect on sperm. Radiation-induced depletion of the α-tocopherol pool in semen disappears at a later period.
Keywords: ionizing radiation, rabbits, seminal plasma, natural antioxidants
Grain barley starch as a gelling agent of nutrient media for cultivation of anthers and isolated embryos of H. vulgare L.
Authors: Bilynska O. V. 
Published: October 2020

Aim. Determination the possibility of agar replacement with normal and waxy type starches produced from barley seeds in the nutrient media for spring barley haploid production. Methods. Anthers of spring barley line DH00-126 were inoculated on inductive media containing N6 macro-, MS micronutrients, organic supplements, maltose (9.0 %) and differed in solidifying agents (agar, starch from barley seeds or chemically modified starch D5a-1). Trophic capacities of barley starch were determined both in anther and embryo culture of barley. Results. It was determined that barley starch of waxy type was not suitable for solidifying of nutrient medium. Use of normal type barley starch (6.5 %) resulted in sufficient decrease in the frequency of green plant regeneration. At the same time, this modification had no effect on the number of morphogenic anthers. Barley starch was inferior to pea starch in the ability to support seedling growth in embryo culture in vitro. Conclusions. Barley starch of normal type has worse trophic capacities in comparison to pea starch in embryo culture. It was appeared barley starch to be a less suitable gelling agent of medium for spring barley haploid production in anther culture in vitro than agar and chemically modified starch D5a-1.
Keywords: Hordeum vulgare L., anther culture in vitro, embryo culture in vitro, agar, barley starch.
Natives of Ukraine – famous scientists abroad
Authors: Piskun R. P. , Hrynchak N. M. , Shkarupa V. M. , Sprut O. V. , Chlestova S. S. 
Published: October 2020

Aim. To highlight the distinguished names and dates of scientific activity of Ukrainian scientists who were born and educated in Ukraine and who have enriched with their scientific achievements the world biological and medical sciences. Methods. Study of biobibliographic editions, in particular personal indexes and important sources of basic scientific researches, which record the achievements of Ukrainian scientists, as well as summarize their contributions to the national and world science, culture, information about education. Results. The published information about the activity of Ukrainian scientists is of undeniable interest to all who are interested in the achievements of world and Ukrainian biological science. It is emphasized that the scientist is not only a researcher, worker and creator of the new, but also a fighter. All the life of a scientist - the struggle for the achievement of this goal, for the disclosure of the secrets of nature, for the recognition of their works, discoveries, laws, for their promulgation and approval. Unfortunately, we cannot cover the whole list of well-known Ukrainian scientists, since great people are brilliant, but we hope that every prominent scientist will not be forgotten. Conclusions. Biographies of prominent scientists from Ukraine will help them to get into their worldview, to feel the unbridled passion of the research, to understand the way they think, to trace the way in which they came to their discoveries. It is our duty to know our history, our luminaries of science, technology, and culture.
Keywords: Ukraine, scientists, biologists, doctors, researchers.
Rossel Vien, un écrivain de la clandestinité, génial et subversif
Authors: Mulaire Bernard 
Published: October 2020

Originaire du Québec, Rossel Vien a vécu la majeure partie de sa vie au Manitoba où il a mené une vie publique consacrée aux médias, à l’histoire et à la poésie. Sous des pseudonymes, il a publié des nouvelles à thématique homosexuelle tant au Québec qu’au Manitoba. Ce faisant, il a exercé dans l’anonymat une présence subversive à Saint-Boniface. Le milieu conservateur de ce haut lieu franco-manitobain avait besoin des multiples talents de Rossel Vien, mais ne pouvait admettre sa différence. Ce texte aborde l’homme et l’oeuvre sous cette double réalité. La première partie situe Rossel Vien dans le contexte historique et social du Manitoba français qu’il a connu. Une analyse de sa nouvelle « Le juge » illustre l’ampleur de l’action dérangeante qui fut la sienne. La seconde partie cerne la place qu’il occupe dans l’histoire de la littérature canadienne de langue française à thématique homosexuelle, québécoise vu les circonstances de son époque. Sa nouvelle « Un homme de trente ans » révèle à quel point il mérite de prendre place parmi les précurseurs qui ont permis à ce qui allait devenir la littérature à thématique gaie de s’affirmer au grand jour, libérée des préjugés et des interdits qui avaient prévalu jusqu’alors.
Le concert participatif. Une forme efficiente pour partager la médiation de la musique classique
Authors: Prévost-Thomas Cécile 
Published: October 2020

À partir de l’observation deLa nuit des Mayas, concert participatif issu du dispositif de concerts-médiationMusiques entre les lignes, conçu par Thierry Weber à la Haute École de Musique de Lausanne, cet article propose de mesurer les différentes dimensions, effets et enjeux du concept de participation à travers son application au secteur de la médiation de la musique.
Priekšvārds
Authors: Šteinberga Airisa 
Published: October 2020

RTU Inženierzinātņu vēstures pētniecības centra (IVPC) sagatavotajā ceturtajā zinātniskajā žurnālā publicēti septiņi pētījumi par Rīgas Politehnikuma (RP) / Rīgas Politehniskā institūta (RPI) studentiem, absolventiem un mācībspēkiem, kā arī ar citiem ar inženierzinātnēm saistītiem jautājumiem. Zinātnisko publikāciju autori ir Latvijas zinātnieki, zinātņu vēsturnieki, muzejnieki un pedagogi. Rakstu pamatā galvenokārt ir RTU 60. starptautiskās zinātniskās konferences 2019. gada 10. oktobrī nolasītie referāti. Pētījumu tematika ir RP / RPI studentu, absolventu un mācībspēku darbība, inženierzinātņu un biedrību vēsture.
In Memoriam
Authors: Zigmunde Alīda 
Published: October 2020

Mašīnzinību, transporta un aeronautikas fakultātes (MTAF) un konferenču un sporta centra «Ronīši» saimniecības pārvaldnieks, RTU Goda darbinieks (2015) Aivars Andruškins.Rīgas Politehniskā institūta (RPI) Ķīmijas fakultātes dekāns (1971–1974) ķīmiķis Jezups Bindars.RTU laikraksta «Jaunais Inženieris» redaktore (1988–2000) un redaktora vietniece (2000–2008), RTU Goda darbiniece (1985) Mudīte Eizentāle.RTU Inženierekonomikas un vadības fakultātes lietvede Ilze Mazure.RTU Inženierekonomikas un vadības fakultātes (IEVF) profesors, RTU Goda darbinieks (2010) Viktors Nešpors.RTU Elektroenerģētikas fakultātes docents un fakultātes dekāns (1958–1966; 1975–1988), RTU Goda darbinieks (1985) Georgijs Obuševs.Latvijas Republikas Zemessardzes Studentu bataljona pirmais komandieris, Viestura ordeņa kavalieris, ilggadējs Latviešu Virsnieku apvienības valdes priekšsēdētājs, Latvijas Ordeņu brālības domes un valdes loceklis, orientēšanās sporta meistars un Vissavienības kategorijas tiesnesis, atvaļinātais kapteinis Aleksejs Ozoliņš.RTU Dizaina tehnoloģiju institūta lietvede Marija Rutkovska.Latvijas Zinātņu akadēmijas (LZA) akadēmiķis un RTU Goda biedrs (2000) profesors Jānis Stradiņš.RTU ilggadējais asociētais profesors Aivars Šulcs.Rīgas Politehniskā institūta (RPI) / Rīgas Tehniskās universitātes (RTU) docētāja filozofe un folkloriste Renāte Tavare.Materiālzinātnes un lietišķās ķīmijas fakultātes (MLĶF) Polimērmateriālu institūta pētniece un Polimēru materiālu tehnoloģijas katedras vecākā laborante, RTU Goda darbiniece (1997) Velta Tupureina.Rīgas Tehniskās universitātes (RTU) un Rīgas Politehniskā institūta (RPI) darbinieks, bijušais Mehānikas un mašīnbūves institūta Siltumenerģētisko sistēmu katedras vadītājs un studiju programmu direktors profesors Dr. habil. sc. ing. Daniels Turlajs.RTU Mašīnzinību, transporta un aeronautikas fakultātes (MTAF) Aeronautikas institūta direktors profesors Aleksandrs Urbahs.Emeritētais profesors, RTU Goda doktors (1994), inženieris un izgudrotājs Reinhards Vītols.RTU darbinieks un mācībspēks, darba aizsardzības speciālists, RTU Goda darbinieks (2017) praktiskais docents Valdis Ziemelis.
The Clinicopathologic Characteristics and Genetic Alterations of Gastric Cancer Patients According to the Lauren Classification
Authors: Cheng Han-Fang , Huang Kuo-Hung , Chen Ming-Huang , Fang Wen-Liang , Lin Chien-Hsing , Chao Yee , Lo Su-Shun , Li Anna Fen-Yau , Wu Chew-Wun , Shyr Yi-Ming 
Published: October 2020

Objective
The Lauren classification is an important histologic classification of gastric cancer (GC) with different biological behaviors between histologic types.

Background
To date, there are few reports on the genetic alterations and survival differences between different histologic types according to the Lauren classification.

Methods
In total, 433 GC patients undergoing surgery were enrolled. The clinicopathologic features, prognoses, and genetic alterations of the different Lauren types were compared.

Results
Diffuse-type GC was associated with a younger age, female predominance, more Borrmann type 3 and 4 tumors, more advanced pathologic tumor (T) and node (N) categories, more tumor recurrences (especially peritoneal recurrence), and worse 5-year overall survival and disease-free survival rates than intestinal-type GC and mixed-type GC. Regarding genetic alterations, mixed-type GC was associated with more TP53 mutations than intestinal-type GC and diffuse-type GC. Multivariate analysis demonstrated the following independent prognostic factors: age, Lauren classification, and pathologic T and N categories. Regarding mixed-type GC, diffuse-type major tumors were associated with more lymphovascular invasion, a more advanced N category and tumor, node, metastasis stage, and fewer PI3K/AKT pathway mutations than intestinal-type major tumors.

Conclusions
Diffuse-type GC had unfavorable clinicopathologic features and a worse prognosis than intestinal-type GC. For mixed-type GC, the clinicopathologic features and genetic alterations were different between intestinal-type major tumors and diffuse-type major tumors.
Acetyl‐l‐carnitine restores choline acetyltransferase activity in the hippocampus of rats with partial unilateral fimbria‐fornix transection
Authors: Piovesan Paola , Quatrini Gianni , Pacifici Licia , Taglialatela Giulio , Angelucci Luciano 
Published: July 2002

AbstractTransection of the fimbria‐fornix bundle in adult rats results in degeneration of the septo‐hippocampal cholinergic pathway, reminiscent of that occurring in aging as well as Alzheimer disease. We report here a study of the effect of a treatment with acetyl‐l‐carnitine (ALCAR) in three‐month‐old Fischer 344 rats bearing a partial unilateral fimbria‐fornix transection. ALCAR is known to ameliorate some morphological and functional disturbances in the aged central nervous system (CNS). We used choline acetyltransferase (ChAT) and acetyl cholinesterase (AChE) as markers of central cholinergic function, and nerve growth factor (NGF) levels as indicative of the trophic regulation of the medio‐septal cholinergic system. ChAT and AChE activities were significantly reduced in the hippocampus (HIPP) ipsilateral to the lesion as compared to the contralateral one, while no changes were observed in the septum (SPT), nucleus basalis magnocellularis (NBM) or frontal cortex (FCX). ALCAR treatment restored ChAT activity in the ipsilateral HIPP, while AChE levels were not different from those of untreated animals, and did not affect NGF content in either SPT or HIPP.
Modulation of interleukin‐1 receptos in the neuro‐endocrine‐immune axis
Authors: Takao T. , Hashimoto K. , De Souza E.B. 
Published: July 2002

AbstractInterleukin‐1 (IL‐1) receptors with kinetics, pharmacological and biochemical characteristics of type I IL‐1 receptors have been identified in the mouse neuro‐endocrine‐immune axis. In the present study, we examined the in‐vitro and in‐vivo modulation of IL‐1 receptors by stress and endotoxin treatment. The treatment of AtT‐20 mouse pituitary adenoma cells for 24 hr with neuro‐endocrine mediators of stress such as corticotropin releasing factor (CRF) and catecholamine (β2 adrenergic) receptor agonists produced a dose‐dependent increase in cAMP and [125I]IL‐1α binding. In contrast, somatostatin and dexamethasone significantly inhibited CRF‐stimulated cAMP production and decreased both basal and CRF‐mediated increase of [125I]IL‐1α binding. Furthermore, in keeping with the effects of stress mediators to upregulate IL‐1 receptors in AtT‐20 cells, ether‐laparotomy stress in mice resulted in a significant increase in [125I]IL‐1α binding in the pituitary with no significant alterations observed in the brain; in contrast, [125I]oCRF binding in the pituitary was significantly decreased after the ether‐laparotomy stress.Next, we investigated the modulation of IL‐1β levels and [125I]IL‐1α binding following endotoxin lipopolysaccharide (LPS) treatment. IL‐1β levels were dramatically increased in the peripheral tissues (pituitary, tests and spleen) at 2–6 hr after a single LPS injection (30 μg LPS/mouse) However, no significant changes were observed in brain (hippocampus and hypothalamus). [125I]IL‐1α binding in the pituitary gland, liver, spleen and testis was significantly decreased at 2 hr following a single administration of both low (30 μg LPS/mouse) and high (300 μg LPS/mouse) doses of endotoxin. [125I]IL‐1α binding in the hippocampus was not significantly altered at 2 hr by a low dose of LPS and was significantly decreased by high dose administration of LPS (300 μg/mouse). Following two LPS injections (at 0 and 12 hr), dramatic increases in IL‐1β concentrations in the hypothalamus, hippocampus, spleen and testis were observed at 2 hr after the second LPS injection; a small but statistically nonsignificant change was evident in the pituitary. Moreover, dramatic decreases in [125I]IL‐1α binding were seen after two injections of 30 μg LPS/mouse in both central and peripheral tissues. These data provide further support for a role for IL‐1 in co‐ordinating neuro‐endocrine‐immune responses to stress and infection.