bluuebunny/crossref_metadata_2025_split huggingface dataset:
Volcanic Plume Aging During Passive Degassing and Low Eruptive Events of Etna and Stromboli Volcanoes
Authors: Pianezze J. , Tulet P. , Foucart B. , Leriche M. , Liuzzo M. , Salerno G. , Colomb A. , Freney E. , Sellegri K. 
Published: October 2019

AbstractVolcanic gases and aerosols emissions from passive degassing or low eruptive events are now included in most climate models despite large uncertainties still exist about their injection height and their temporal and spatial variability. The aim of this study is to quantify the evolution of the gas and aerosols inside volcanic plumes with high kilometric‐resolution simulations. With online chemistry and aerosols, these simulations are carried out together with in situ measurements of aerosol and gas‐phase properties to assess the impact of Etna and Stromboli volcanic plumes produced by passive degassing and regular Strombolian activity, respectively. Comparison between simulation and observations show that the simulation reproduces the main characteristics of the volcanic plume evolution and confirms that volcanic plumes produced by passive degassing or low eruptive events have a strong impact on cloud condensation nuclei (CCN) formation increasing the number of CCN by a factor of 5. It was also shown that depending on the plume location, the aerosols will act as CCN at different distance from the vent. In the marine atmospheric boundary layer, the aerosols will act as CCN at proximity to the vent (less than 50 km) because of strong condensation sink inhibiting nucleation. In comparison, in the free troposphere, aerosols will act as CCN far from the vent, at more than 200 km. To the best of our knowledge, this study using in situ measurements as well as subkilometric simulations is unique.
The Production and Fate of Volatile Organosulfur Compounds in Sulfidic and Ferruginous Sediment
Authors: Wilkening Jean V. , Turchyn Alexandra V. , Redeker Kelly R. , Mills Jennifer V. , Antler Gilad , Carrión Ornella , Todd Jonathan D. 
Published: October 2019

AbstractVolatile organic sulfur compounds (VOSCs) link the atmospheric, marine, and terrestrial sulfur cycles in marine and marginal marine environments. Despite the important role VOSCs play in global biogeochemical sulfur cycling, less is known about how the local geochemical conditions influence production and consumption of VOSCs. We present a study of dimethyl sulfide (DMS), methanethiol (MeSH), and dimethylsulfoniopropionate (DMSP) in sulfide‐rich (sulfidic) and iron‐rich (ferruginous) salt marsh sediment from north Norfolk, UK. Initial results illustrate the importance of minimizing time between sampling in remote field locations and laboratory analysis, due to rapid degradation of VOSCs. With rapid analysis of sediment from different depths, we observe high concentrations of DMS, MeSH, and DMSP, with concentrations in surface sediment an order of magnitude higher than those in previous studies of surface water. We measure systematic differences in the concentration and depth distribution of MeSH and DMS between sediment environments; DMS concentrations are higher in ferruginous sediment, and MeSH concentrations are higher in sulfidic sediment. With repeated measurements over a short time period, we show that the degradation patterns for DMS and MeSH are different in the ferruginous versus sulfidic sediment. We discuss potential biogeochemical interactions that could be driving the observed differences in VOSC dynamics in ferruginous and sulfidic sediment.
Barotropic Instability of a Cyclone Core at Kilometer‐Scale Resolution
Authors: Leutwyler David , Schär Christoph 
Published: October 2019

AbstractSecondary disturbances spawning frontal waves along the fronts of mature midlatitude low‐pressure systems were identified decades ago from satellite images and during field campaigns. Today's flagship supercomputers allow performing simulations at kilometer‐scale resolution on computational domains covering the entire lifecycle of synoptic‐scale systems and thus enable explicit representation of small‐scale disturbances embedded in large‐scale circulations. Here we demonstrate these capabilities in two different types of kilometer‐scale simulations. The first is a 10‐day‐long near‐global simulation of an idealized moist baroclinic wave, performed at 1 km grid spacing and employing 16,001 × 36,006 × 60 grid points. The second is a real‐case simulation of an extratropical low‐pressure system, driven by the European Centre for Medium‐Range Weather Forecasts's operational analysis. At kilometer‐scale resolution, both simulations display clear evidence of embedded mesoscale vortices spawning along frontal systems of mature extratropical cyclones. The vortices appearing in the real‐case simulation can also be identified in satellite imagery of the system. The simulated developments are due to a barotropic instability mechanism and driven by strong low‐level horizontal wind shear. While the simulation of the frontal systems is amenable at model resolutions around 10–50 km, the instability mechanism itself relies on the representation of a narrow shear zone, requiring about 5 times finer resolution. Results suggest that the flow regimes suppressing or fostering barotropic vortices can coexist in the same synoptic system. Far away from the cyclone core, the instability is suppressed by deformation associated with the large‐scale flow, while close to the mature cyclone core, the narrow frontal structure becomes unstable.
Mercury concentrations in biota in the Mediterranean Sea, a compilation of 40 years of surveys
Authors: Cinnirella S. , Bruno D. E. , Pirrone N. , Horvat M. , Živković I. , Evers D. C. , Johnson S. , Sunderland E. M. 
Published: October 2019

AbstractThe Mediterranean Region has a long lasting legacy of mercury mining activities and a high density of sub-marine volcanoes that has strongly contributed to its mercury budget. In the last forty years, there have been recorded increases in mercury concentrations in biota that have spurred a growing number of research activities to assess the impact of mercury pollution on human health and environment. Field investigations that quantify mercury concentrations in marine biota have led to a large amount of experimental data scattered in many peer-reviewed publications making it difficult for modelling applications and regional environmental assessments. This paper reviews existing peer-reviewed literature and datasets on mercury concentration in marine flora and fauna (Animal, Plants and Chromista Kingdoms) in the Mediterranean basin. A total of 24,465 records have been retrieved from 539 sources and included in Mercury in Mediterranean Biota (M2B). Well-defined specimens account for 24,407 observations, while a few records include generic plankton and unidentified fish species. Among all considered species, we selected Diplodus sargus, Sardina pilchardus, Thunnus thynnus and Xiphias gladius to show trends of mercury concentration against WHO and EU limits. Few notes on how M2B is intended to support the implementation of the Minamata Convention on Mercury by a user-driven Knowledge Hub are finally reported.
Generation of highly integrated multiple vivid colours using a three-dimensional broadband perfect absorber
Authors: Kim Soo-Jung , Jung Pil-Hoon , Kim Wonjoong , Lee Heon , Hong Sung-Hoon 
Published: October 2019

AbstractThe colour printing technology based on interactions between geometric structures and light has various advantages over the pigment-based colour technology in terms of nontoxicity and ultrasmall pixel size. The asymmetric Fabry–Perot (F–P) cavity absorber is the simplest light-interacting structure, which can easily represent and control the colour by the thickness of the dielectric layer. However, for practical applications, an advanced manufacturing technique for the simultaneous generation of multiple reflective colours is required. In this study, we demonstrate F–P cavity absorbers with micropixels by overcoming the difficulties of multi-level pattern fabrication using a nanoimprinting approach. Our asymmetric F–P cavity absorber exhibited a high absorption (approximately 99%) in a wide visible light range upon the incorporation of lossy metallic materials, yielding vivid colours. A high-resolution image of eight different reflective colours was obtained by a one-step process. This demonstrates the potential of this technology for device applications such as high-resolution colour displays and colour patterns used for security functions.
Organic mulches reduce crop attack by sweetpotato weevil (Cylas formicarius)
Authors: Rehman Mudassir , Liu Jian , Johnson Anne C. , Dada Taiwo Esther , Gurr Geoff M. 
Published: October 2019

AbstractMulching with organic materials is a management practice with long history for weed suppression, soil water conservation and erosion control. Its potential impact on crop pests is less well explored. Here we report its utility for reducing crop damage by the serious pest, sweetpotato weevil (Cylas formicarius). Laboratory bioassays measured the response of adult female weevils to sweetpotato storage roots beneath mulches of fresh or dried plant materials. Weevils were significant repelled by fresh basil, catnip, basil lime and dry eucalyptus, cypress, lucerne and sugarcane. A subsequent field study found that mulches of dry cypress, eucalyptus and lucerne reduced movement of weevils from a release point to reach sweetpotato plants and lowered level of damage to storage roots. Results demonstrate that mulching with organic materials merits further testing as part of the integrated management of sweetpotato weevil, particularly to protect developing storage roots during dry periods when soil cracking can facilitate access by pests.
Using the Belinfante momentum to retrieve the polarization state of light inside waveguides
Authors: Ginis Vincent , Liu Lulu , She Alan , Capasso Federico 
Published: October 2019

AbstractCurrent day high speed optical communication systems employ photonic circuits using platforms such as silicon photonics. In these systems, the polarization state of light drifts due to effects such as polarization mode dispersion and nonlinear phenomena generated by photonic circuit building blocks. As the complexity, the number, and the variety of these building blocks grows, the demand increases for an in-situ polarization determination strategy. Here, we show that the transfer of the Belinfante momentum to particles in the evanescent field of waveguides depends in a non-trivial way on the polarization state of light within that waveguide. Surprisingly, we find that the maxima and minima of the lateral force are not produced with circularly polarized light, corresponding to the north and south poles of the Poincaré sphere. Instead, the maxima are shifted along the great circle of the sphere due to the phase differences between the scattered TE and TM components of light. This effect allows for an unambiguous reconstruction of the local polarization state of light inside a waveguide. Importantly, this technique depends on interaction with only the evanescent tails of the fields, allowing for a minimally invasive method to probe the polarization within a photonic chip.
The influence that different urban development models has on PM2.5 elemental and bioaccessible profiles
Authors: Polezer Gabriela , Oliveira Andrea , Potgieter-Vermaak Sanja , Godoi Ana F. L. , de Souza Rodrigo A. F. , Yamamoto Carlos I. , Andreoli Rita V. , Medeiros Adan S. , Machado Cristine M. D. , dos Santos Erickson O. , de André Paulo A. , Pauliquevis Theotonio , Saldiva Paulo H. N. , Martin Scot T. , Godoi Ricardo H. M. 
Published: October 2019

AbstractLimited studies have reported on in-vitro analysis of PM2.5 but as far as the authors are aware, bioaccessibility of PM2.5 in artificial lysosomal fluid (ALF) has not been linked to urban development models before. The Brazilian cities Manaus (Amazon) and Curitiba (South region) have different geographical locations, climates, and urban development strategies. Manaus drives its industrialization using the free trade zone policy and Curitiba adopted a services centered economy driven by sustainability. Therefore, these two cities were used to illustrate the influence that these different models have on PM2.5in vitro profile. We compared PM2.5 mass concentrations and the average total elemental and bioaccessible profiles for Cu, Cr, Mn, and Pb. The total average elemental concentrations followed Mn > Pb > Cu > Cr in Manaus and Pb > Mn > Cu > Cr in Curitiba. Mn had the lowest solubility while Cu showed the highest bioaccessibility (100%) and was significantly higher in Curitiba than Manaus. Cr and Pb had higher bioaccessibility in Manaus than Curitiba. Despite similar mass concentrations, the public health risk in Manaus was higher than in Curitiba indicating that the free trade zone had a profound effect on the emission levels and sources of airborne PM. These findings illustrate the importance of adopting sustainable air quality strategies in urban planning.
Serum markers of type III and IV procollagen processing predict recurrence of fibrosis in liver transplanted patients
Authors: Nielsen Mette Juul , Villesen Ida Falk , Gudmann Natasja Stæhr , Leeming Diana Julie , Krag Aleksander , Karsdal Morten Asser , Zimmermann Tim , Schuppan Detlef 
Published: October 2019

AbstractFollowing liver transplantation (LT), 10–30% of patients develop recurrent cirrhosis (RC). There is an urgent need for predictive non-invasive markers for improved monitoring of these patients. Here we studied extracellular matrix biomarkers as predictors of RC after LT. Forty-seven LT patients were divided into groups of fast, intermediate or non-progressors towards RC (<1 year, 3–5 years or no advanced fibrosis >5 years after LT), assessed by follow-up liver biopsies. Markers of interstitial matrix type III and V collagen formation (PRO-C3 and PRO-C5), basement membrane type IV collagen formation (PRO-C4) and degradation (C4M) were assessed in serum samples collected 3, 6 and 12 months post-LT using specific ELISAs. PRO-C3, PRO-C4, and C4M were elevated in fast progressors compared to non-progressors 3 months after LT. C4M and PRO-C4 additionally differentiated between intermediate and fast progressors at 3 months. PRO-C3 was best predictor of survival, with LT patients in the highest PRO-C3 tertile having significantly shorter survival time. This shows that interstitial matrix and basement membrane remodeling in RC may be distinguishable. Markers originating from different sites in the extracellular matrix could be valuable tools for a more dynamic monitoring of patients at risk of RC. However, this needs validation in larger cohorts.
The molecular mechanisms of LncRNA-correlated PKM2 in cancer metabolism
Authors: Tao Ting , Wu Shiyuan , Sun Zheng , Ma Wei , Zhou Sichun , Deng Jun , Su Qiongli , Peng Mei , Xu Gaosheng , Yang Xiaoping 
Published: October 2019

AbstractReprogrammed metabolism is an important hallmark of cancer cells. Pyruvate kinase (PK) is one of the major rate-limiting enzymes in glucose metabolism. The M2 isoform of PK (PKM2), is considered to be an important marker of metabolic reprogramming and one of the key enzymes. Recently, through the continuous development of genome-wide analysis and functional studies, accumulating evidence has demonstrated that long non-coding RNAs (LncRNAs) play vital regulatory roles in cancer progression by acting as either potential oncogenes or tumor suppressors. Furthermore, several studies have shown that up-regulation of PKM2 in cancer tissues is associated with LncRNAs expression and patient survival. Thus, scientists have begun to unveil the mechanism of LncRNA-associated PKM2 in cancer metabolic progression. Based on these novel findings, in this mini-review, we summarize the detailed molecular mechanisms of LncRNA related to PKM2 in cancer metabolism. We expect that this work will promote a better understanding of the molecular mechanisms of PKM2, and provide a profound potential for targeting PKM2 to treat tumors.
Long noncoding RNA FAM83A-AS1 facilitates hepatocellular carcinoma progression by binding with NOP58 to enhance the mRNA stability of FAM83A
Authors: He Jinyu , Yu Jiao 
Published: October 2019

Abstract
Hepatocellular carcinoma (HCC), as one of the commonest cancers globally, is a primary malignancy in human liver with a characteristic of high mortality rate. Long noncoding RNAs (lncRNAs) are confirmed to be implicated with multiple cancers including HCC. LncRNA FAM83A-AS1 has also been validated as an oncogene in lung cancer, but its mechanism in HCC is poorly understood. Our research is intended to investigate the underlying mechanism of FAM83A-AS1 in HCC. In the present study, we found the abundantly increased expression level of FAM83A-AS1 in HCC tissues and cells. FAM83A-AS1 inhibition hampered cell proliferation, migration and elevated cell apoptosis in HCC. Moreover, FAM83A-AS1 could positively regulate FAM83A, and FAM83A could also promote the progression of HCC. In addition, FAM83A-AS1 and FAM83A were both verified to bind with NOP58, and FAM83A-AS1 enhanced the mRNA stability of FAM83A by binding with NOP58. In rescue assays, the suppressed influence of down-regulated FAM83A-AS1#1 on cell proliferation, migration as well as the accelerated influence of FAM83A-AS1#1 knockdown on cell apoptosis could be partially recovered by overexpression of FAM83A. In conclusion, FAM83A-AS1 facilitated HCC progression by binding with NOP58 to enhance the stability of FAM83A. These findings offer a novel biological insight into HCC treatment.
An Application of eHealth Technology Toward the Digitization of the Health Records of Older Patients With Cochlear Implants
Authors: Tognola Gabriella , Murri Alessandra , Cuda Domenico 
Published: October 2019

Purpose
Despite the current legislative indications toward the digitization of patient health records, 80% of health data are unstructured and in a format that cannot be used in electronic archives or in registries of diseases. An innovative automated system is here proposed to efficiently retrieve and digitize clinical information from original unstructured ear, nose, and throat (ENT) medical records, in order to reduce the manual workload in the retrieval and digitization process.

Method

The system, based on an eHealth technology named
cognitive computing
, interprets medical reports to transform unstructured clinical data (e.g., narrative text) into a structured digital format. The system has been tailored to handle the reports of aged cochlear implant (CI) patients by digitizing the information typically requested in electronic CI registries and by the current ENT/audiology guidelines. Results were obtained from the reports generated by an outpatient ENT care service from 52 older adult CI patients.

Results
The system allowed a quick and automated interpretation and retrieval of all the information required, such as the patient's medical history, risk factors, examination outcomes, communicative performances before and after CI implantation, and CI settings. The accuracy of the system in correctly interpreting and retrieving the above information from the original unstructured medical reports was very good (recall = 0.78; precision = 0.95). The system allowed to reduce the time needed to manually digitize the information from 20–30 min/report to only 20 s/report.

Conclusion
The proposed system is a viable solution for the automated digitization of unstructured health data as recommended by the ENT/audiology clinical best practices.
Capital investments in the context of sustainable development of railways
Authors: Kharchenko Olesia , Okorokov Andrii , Vernigora Roman , Tsuprov Pavlo , Papakhov Oleksandr , Logvinova Nataliia 
Published: October 2019

Ukraine, due to its geographical position and developed transport infrastructure, has significant potential as a transit country, primarily in the supply chain of trade between Asia and Europe. According to the estimates of the British Institute for Transport Rendell Ukraine, the transit coefficient of Ukraine is 3,75 (with a maximum of 5); This is the best indicator among the countries of Europe (for comparison, in Poland, which occupies the second place, this indicator is 2,92).Nowadays, Ukraine uses its transit potential extremely insufficiently and inefficiently; over the past 10 years, the volume of transit traffic through the territory of Ukraine has declined by more than 2,5 times, primarily due to the fall in transit traffic by rail. One of the reasons for this situation is, of course, the general political and economic situation in the country. However, there are a number of other negative factors that prevent Ukraine from fully and effectively using its transit potential. These problems lie both in the purely technical plane (deterioration of transport infrastructure and rolling stock, lack of capacity of the main transport routes, underdevelopment of logistics terminals in the country and at land borders, difference in width with the European railway system) and the legislato-thick (high level of port dues, bureaucratization and regulation of customs procedures, lack of flexible tariff policy for carriers, etc.).
Operative technical tricks and 12-month outcomes of diverticular peroral endoscopic myotomy (D-POEM) in patients with symptomatic esophageal diverticula
Authors: Maydeo Amit , Patil Gaurav K. , Dalal Ankit 
Published: October 2019

Abstract
Background Submucosal tunneling diverticular septotomy by diverticular peroral endoscopic myotomy (D-POEM) has emerged as an alternative to surgery for symptomatic esophageal diverticula, but its medium to long-term outcomes are currently unexplored.
Methods D-POEM for patients with symptomatic esophageal diverticula was prospectively studied to assess its safety and the 12-month outcomes.
Results 25 patients (72 % male; median age 61 years [range 48 – 88]) with a Zenker’s diverticulum (n = 20) or epiphrenic diverticulum (n = 5) were included. Major indications were dysphagia, recurrent bronchoaspiration, and foreign body sensation in 20 patients (80 %), with a mean symptom duration of 2.5 years (range 1 – 4). Complete submucosal tunneling septotomy was achieved in a mean of 36 minutes (range 25 – 45), with 100 % technical success. The median hospitalization was 5 days (range 4 – 10). The mean (standard deviation) Eckardt Score improved significantly from 13.2 (1.0) at baseline to 3.2 (1.4) at 12 months (P < 0.001) with clinical success in 19/22 patients (86 %) and no long-term adverse events.
Conclusions D-POEM appears safe and durable in patients with esophageal diverticula. Further multicenter studies with a larger patient cohort are warranted.