bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of pharmaceutical and recreational drug poisoning
Authors: Mégarbane Bruno , Oberlin Mathieu , Alvarez Jean-Claude , Balen Frederic , Beaune Sébastien , Bédry Régis , Chauvin Anthony , Claudet Isabelle , Danel Vincent , Debaty Guillaume , Delahaye Arnaud , Deye Nicolas , Gaulier Jean-Michel , Grossenbacher Francis , Hantson Philippe , Jacobs Frédéric , Jaffal Karim , Labadie Magali , Labat Laurence , Langrand Jérôme , Lapostolle Frédéric , Le Conte Philippe , Maignan Maxime , Nisse Patrick , Sauder Philippe , Tournoud Christine , Vodovar Dominique , Voicu Sebastian , Claret Pierre-Géraud , Cerf Charles 
Published: November 2020

AbstractBackgroundPoisoning is one of the leading causes of admission to the emergency department and intensive care unit. A large number of epidemiological changes have occurred over the last years such as the exponential growth of new synthetic psychoactive substances. Major progress has also been made in analytical screening and assays, enabling the clinicians to rapidly obtain a definite diagnosis.MethodsA committee composed of 30 experts from five scientific societies, theSociété de Réanimation de Langue Française(SRLF), theSociété Française de Médecine d’Urgence(SFMU), theSociété de Toxicologie Clinique(STC), theSociété Française de Toxicologie Analytique(SFTA) and theGroupe Francophone de Réanimation et d’Urgences Pédiatriques(GFRUP) evaluated eight fields: (1) severity assessment and initial triage; (2) diagnostic approach and role of toxicological analyses; (3) supportive care; (4) decontamination; (5) elimination enhancement; (6) place of antidotes; (7) specificities related to recreational drug poisoning; and (8) characteristics of cardiotoxicant poisoning. Population, Intervention, Comparison, and Outcome (PICO) questions were reviewed and updated as needed, and evidence profiles were generated. Analysis of the literature and formulation of recommendations were then conducted according to the GRADE®methodology.ResultsThe SRLF-SFMU guideline panel provided 41 statements concerning the management of pharmaceutical and recreational drug poisoning. Ethanol and chemical poisoning were excluded from the scope of these recommendations. After two rounds of discussion and various amendments, a strong consensus was reached for all recommendations. Six of these recommendations had a high level of evidence (GRADE 1±) and six had a low level of evidence (GRADE 2±). Twenty-nine recommendations were in the form of expert opinion recommendations due to the low evidences in the literature.ConclusionsThe experts reached a substantial consensus for several strong recommendations for optimal management of pharmaceutical and recreational drug poisoning, mainly regarding the conditions and effectiveness of naloxone andN-acetylcystein as antidotes to treat opioid and acetaminophen poisoning, respectively.
Research on image recognition of intangible cultural heritage based on CNN and wireless network
Authors: Liu Enmao 
Published: November 2020

AbstractThe image of national costumes is the main way of presenting the digitalization of intangible cultural heritage and provides important resources for educational informatization. How to use modern information technology to efficiently retrieve images of national costumes has become a hot research topic. Due to the diverse styles and colorful colors of ethnic costumes, it is difficult to accurately describe and extract visual features. In view of the above problems, this paper proposes an image recognition model of intangible cultural heritage based on CNN and wireless network. First of all, the clothing images of ethnic settlements and ethnic museums are acquired through wireless network transmission, so as to construct an image material library of intangible cultural heritage. Secondly, the CNN algorithm is used to train and optimize the national costume image samples, extract the high-level semantic features of the national costume image and finally realize the efficient retrieval of the national costume image educational resources. This model lays a good foundation for the informatization of national costumes and contributes to the inheritance and protection of intangible cultural heritage.
Generalized hypergeometric distribution and its applications on univalent functions
Authors: Themangani Rajavadivelu , Porwal Saurabh , Magesh Nanjundan 
Published: November 2020

AbstractThe purpose of the present paper is to introduce a generalized hypergeometric distribution and obtain some necessary and sufficient conditions for generalized hypergeometric distribution series belonging to certain classes of univalent functions associated with the conic domains. We also investigate some inclusion relations. Finally, we discuss an integral operator related to this series.
Optimal selection of injection doses and injection timings for insulin therapy in a limited time
Authors: Liu Shouzong , Yu Ling , Huang Mingzhan , Shi Xiangyun 
Published: November 2020

AbstractIn this paper, we study the injection strategies of insulin for the impulsive therapy of diabetes in a limited time. According to whether we consider the risk of hypoglycemia or not, we develop two different control objectives and investigate three different injection strategies for each control objective. We apply a time-rescaling method to overcome technical obstacles in optimal impulsive control and compute the gradient formulas of cost functions with respect to injection doses and injection timings. By means of numerical simulations we get the optimal injection doses and injection timings for each injection strategy. Our study indicates that for the control objective without considering the risk of hypoglycemia, the optimal injection timing control is more effective than the optimal injection dose control, whereas the mixed control achieves almost the same effect as the optimal injection timing control. For the other control objective considering the risk of hypoglycemia, the optimal injection timing control performs better than the optimal injection dose control in avoiding emergence of hypoglycemia, and the mixed control provides the best strategy in preventing hyperglycemia from occurrence.
A nonlinear generalized subdivision scheme of arbitrary degree with a tension parameter
Authors: Zhang Zeze , Zheng Hongchan , Zhou Jie , Pan Lulu 
Published: November 2020

AbstractIn this paper, a nonlinear generalized subdivision scheme of arbitrary degree with a tension parameter is presented, which refines 2D point-normal pairs. The construction of the scheme is built upon the stationary linear generalized subdivision scheme of arbitrary degree with a tension parameter, by replacing the weighted binary arithmetic average in the linear scheme with the circle average. For such a nonlinear scheme, we investigate its smoothness and get that it can reach $C^{1}$

C
1

with suitable choices of the tension parameter when degree $m\geq 3$
m
≥
3
. Besides, the nonlinear scheme can reconstruct the circle and the selection of parameters and initial normal vectors can effectively control the shape of the limit curves.
Bifurcation and exact solutions for the ($2+1$)-dimensional conformable time-fractional Zoomeron equation
Authors: Li Zhao , Han Tianyong 
Published: November 2020

AbstractIn this paper, the bifurcation and new exact solutions for the ($2+1$2+1)-dimensional conformable time-fractional Zoomeron equation are investigated by utilizing two reliable methods, which are generalized$(G'/G)$(G′/G)-expansion method and the integral bifurcation method. The exact solutions of the ($2+1$2+1)-dimensional conformable time-fractional Zoomeron equation are obtained by utilizing the generalized$(G'/G)$(G′/G)-expansion method, these solutions are classified as hyperbolic function solutions, trigonometric function solutions, and rational function solutions. Giving different parameter conditions, many integral bifurcations, phase portraits, and traveling wave solutions for the equation are obtained via the integral bifurcation method. Graphical representations of different kinds of the exact solutions reveal that the two methods are of significance for constructing the exact solutions of fractional partial differential equation.
Stochastic model of tuberculosis with vaccination of newborns
Authors: Tilahun Getachew Teshome , Belachew Melisew Tefera , Gebreselassie Zinabu 
Published: November 2020

AbstractIn this paper we have proposed a stochastic model for studying the dynamics of tuberculosis (TB) by incorporating vaccination of newly born babies. The total population in this model is subdivided in to four compartments, namely susceptible$S ( t )$S(t), infected$I ( t )$I(t), vaccinated newborns$V ( t ) $V(t), and recovered$R ( t ) $R(t). First, the developed model is expressed and analyzed by the deterministic approach. Since this approach neglects the randomness of the dynamics of the process, it has great limitations in the modeling process. To avoid this kind of issues, we transform the deterministic approach into a stochastic one, which is known to play a significant role by providing additional degree of realism compared to the deterministic approach. The analysis of the model is done employing both approaches. The invariant region, positivity of the solution, equilibrium points and their stability are checked. According to the analysis, we came to realize that the basic reproduction number for the stochastic approach is smaller than the deterministic one. We have conducted various numerical experiments and obtained interesting simulation results which indicate that a combination of increased newborn vaccination and appropriate treatment of infected individuals have a great contribution in combating TB. It is worth mentioning that the simulation results confirm the conclusion drawn from the qualitative analysis of the model.
Integrated resource management pipeline for dynamic resource-effective cloud data center
Authors: Hassan Hanan A. , Maiyza Aya I. , Sheta Walaa M. 
Published: November 2020

AbstractCloud computing is a popular emerging computing technology that has revolutionized information technology through flexible provisioning of computing resources. Therefore, efforts to develop an effective resource management approach have found that implementing efficient resource sharing among multiple customers that considers power saving, service-level agreements, and network traffic simultaneously is difficult. This paper proposes a practical integrated pipeline that can use various algorithms. The performance of each algorithm is evaluated independently to obtain the combination of algorithms that guarantees a resource-effective cloud data center framework. This integrated resource management pipeline approach would optimize performance based on several key performance indicators, such as power saving, network traffic, and service-level agreements, for either the whole system or the end-user. The performance of the proposed resource management framework was evaluated using a real testbed. The results demonstrated that the proactive double exponential smoothing algorithm prevents unnecessary migrations, the MMTMC2 VM selection algorithm improved the quality of service for end-users and reduced overall energy consumption and network traffic, and the medium-fit placement algorithm provided load balancing between active servers and decreased service level agreement violations. The performance comparison illustrated that the combination of these algorithms was considered to be the best solution toward a dynamic resource-effective cloud data center. Our results showed that energy consumption and the total number of migrations decreased by 16.64% and 49.44%, respectively.
The effect of adding goal-directed hemodynamic management for elective patients in an established enhanced recovery program for colorectal surgery: results of quasi-experimental pragmatic trial
Authors: McEvoy Matthew D. , Wanderer Jonathan P. , Shi Yaping , Ramanujan Krishnan S. , Geiger Timothy M. , Shotwell Matthew S. , Shaw Andrew D. , Hawkins Alexander T. , Martin Barbara J. , Mythen Michael G. , Sandberg Warren S. 
Published: November 2020

Abstract
Background
Recent literature has demonstrated that hemodynamic instability in the intraoperative period places patients at risk of poor outcomes. Furthermore, recent studies have reported that stroke volume optimization and protocolized hemodynamic management may improve perioperative outcomes, especially surgical site infection (SSI), in certain high-risk populations. However, the optimal strategy for intraoperative management of all elective patients within an enhanced recovery program remains to be elucidated.

Methods
We performed a pre-post quasi-experimental study to assess the effect of adding goal-directed hemodynamic therapy to an enhanced recovery program (ERP) for colorectal surgery on SSI and other outcomes. Three groups were compared: “Pre-ERP,” defined as historical control (before enhanced recovery program); “ERP,” defined as enhanced recovery program using zero fluid balance; and “ERP+GDHT,” defined as enhanced recovery program plus goal-directed hemodynamic therapy. Outcomes were obtained through our National Surgical Quality Improvement Program participation.

Results
A total of 623 patients were included in the final analysis (Pre-ERP = 246, ERP = 140, and ERP + GDHT = 237). Demographics and baseline clinical characteristics were balanced between groups. We did not observe statistically significant differences in SSI or composite complication rates in unadjusted or adjusted analysis. There was no evidence of association between study group and 30-day readmission. American Society of Anesthesiologists status ≥ 3 and open surgical approach were significantly associated with increased risk of SSI, composite complication, and 30-day readmission (p < 0.05 for all) in all groups.

Conclusions
There was no evidence that addition of goal-directed hemodynamic therapy for all patients in an enhanced recovery program for colorectal surgery affects the risk of SSI, composite complications, or 30-day readmission. Further research is needed to investigate whether there is benefit of goal-directed hemodynamic therapy for select high-risk populations.

Trial registration
NCT03189550. Registered 16 June 2017–Retrospectively registered, https://www.clinicaltrials.gov/ct2/results?cond=&term=NCT03189550&cntry=&state=&city=&dist=
Upper limb muscle atrophy associated with in-hospital mortality and physical function impairments in mechanically ventilated critically ill adults: a two-center prospective observational study
Authors: Nakanishi Nobuto , Oto Jun , Tsutsumi Rie , Akimoto Yusuke , Nakano Yuki , Nishimura Masaji 
Published: November 2020

AbstractBackgroundLower limb muscle atrophy is often observed in critically ill patients. Although upper limb muscles can undergo atrophy, it remains unclear how this atrophy is associated with clinical outcomes. We hypothesized that this atrophy is associated with mortality and impairments in physical function.MethodsIn this two-center prospective observational study, we included adult patients who were expected to require mechanical ventilation for > 48 h and remain in the intensive care unit (ICU) for > 5 days. We used ultrasound to evaluate the cross-sectional area of the biceps brachii on days 1, 3, 5, and 7 and upon ICU discharge along with assessment of physical functions. The primary outcome was the relationship between muscle atrophy ratio and in-hospital mortality on each measurement day, which was assessed using multivariate analysis. The secondary outcomes were the relationships between upper limb muscle atrophy and Medical Research Council (MRC) score, handgrip strength, ICU Mobility Scale (IMS) score, and Functional Status Score for the ICU (FSS-ICU).ResultsSixty-four patients (43 males; aged 70 ± 13 years) were enrolled. The Acute Physiology and Chronic Health Evaluation (APACHE) II score was 27 (22–30), and in-hospital mortality occurred in 21 (33%) patients. The decreased cross-sectional area of the biceps brachii was not associated with in-hospital mortality on day 3 (p= 0.43) but was associated on days 5 (p= 0.01) and 7 (p< 0.01), which was confirmed after adjusting for sex, age, and APACHE II score. In 27 patients in whom physical functions were assessed, the decrease of the cross-sectional area of the biceps brachii was associated with MRC score (r= 0.47,p= 0.01), handgrip strength (r= 0.50,p= 0.01), and FSS-ICU (r= 0.56,p< 0.01), but not with IMS score (r= 0.35,p= 0.07) upon ICU discharge.ConclusionsUpper limb muscle atrophy was associated with in-hospital mortality and physical function impairments; thus, it is prudent to monitor it. (321 words)Trial registrationUMIN 000031316. Retrospectively registered on 15 February 2018.
Simultaneous rupture on conjugate faults during the 2018 Anchorage, Alaska, intraslab earthquake (MW 7.1) inverted from strong-motion waveforms
Authors: Guo Yujia , Miyakoshi Ken , Tsurugi Masato 
Published: November 2020

AbstractAnMW7.1 ~ 50-km-deep intraslab earthquake within the Pacific/Yakutat slab underlying the North American Plate struck Anchorage, southern Alaska, on November 30, 2018. The ground-motion records very close to the source region of the Anchorage earthquake provide an important opportunity to better understand the source characteristics of intraslab earthquakes in this subduction zone. We estimated the kinematic rupture process during this earthquake using a series of strong-motion waveform (0.05–0.4 Hz) inversions. Our inversions clearly indicate that the Anchorage earthquake was a rare intraslab event with simultaneous rupture on two conjugate faults, which are recognized sometimes for shallow crustal earthquakes but rarely for deep intraslab earthquakes. Interestingly, one of the conjugate faults had low aftershock productivity. This fault extends to great depth and may reflect a deep oceanic Moho or a local low-velocity and high-VP/VSzone within the oceanic mantle. Even though the Anchorage earthquake was a rare event due to the conjugate faults, we found that its kinematic source parameters such as the slip amplitude and large slip area nearly equal the global averages derived from source scaling relationships for intraslab earthquakes. Because the source parameters comparable to the global averages were also found for another large intraslab earthquake in the subducting Pacific/Yakutat slab, these source parameters are likely an important source characteristic common to this subduction zone.
Effect of some rhizosphere bacteria on root-knot nematodes
Authors: AbdelRazek Ghena Mamdouh , Yaseen Rabaa 
Published: November 2020

Abstract
Background
Root-knot nematodes are among the world’s most damaging endoparasitic sedentary nematodes, especially, Meloidogyne incognita that infects a wide range of plant hosts. The activity of different antagonistic bacteria was studied for the low-cost and eco-friendly management of M. incognita on eggplant.

Main body
Twenty-five isolates were isolated from rhizosphere soils infected with nematodes. Of these, 6 isolates displayed the highest activity, demonstrating 100% mortality of J2 nematodes under laboratory conditions. Partial sequencing of 16S rRNA gene and phylogenetic analysis was used to identify the selected isolates and they were found to be Paenibacillus amylolyticus, Brevibacillus agri, Gluconobacter frateurii, Beijerinckia mobilis, Achromobacter aloeverae, and Pseudomonas stutzeri. The abilities of the selected isolates to produce hydrogen cyanide, siderophores, chitinase, protease, indole acetic acid, and to dissolve phosphorus were also detected.

Conclusion
The results of the greenhouse experiment indicated that all the tested bacteria had a greatly significant effectiveness for suppressing root-knot nematode M. incognita. Application of all the rhizosphere bacteria and their combinations reduced the number of galls, number of juveniles, egg-masses, eggs, females, and total final population. All bio-agent treatments succeeded in improving the plant growth parameters and increased the microbial density in eggplant rhizosphere.
Chromium (VI) tolerance and bioaccumulation by Candida tropicalis isolated from textile wastewater
Authors: Ilyas Sidra , Bukhari Dilara A. , Rehman Abdul 
Published: November 2020

AbstractIn the present study a yeast strain isolated from industrial wastewater, identified as Candida tropicalis, showed chromium (Cr) tolerance level up to 5 mM. Yeast grown in minimal salt medium containing Cr (VI) ions for 48 h and crude enzyme extracts were tested for chromate reductase activity. Optimum temperature and pH of chromate reductase were 30 °C and pH of 7. The enzyme activity was greatly enhanced in the presence of divalent metal cations. Total protein profile revealed some protein bands were present in hexavalent chromium [Cr (VI)] treated samples but were absent in non-treated samples, especially low molecular-weight protein bands in the mass range of < 25 kDa with greater intensity in Cr (VI) treated samples. Yeast cells were able to uptake Cr (VI) between 21 and 80 mg g− 1 within 2–12-d of time, indicating yeast strain promising potential for Cr (VI) removal from the wastewater. The present study results suggest that C. tropicalis is a suitable candidate for bioremediating chromium ions from the contaminated-environment.
Activated carbonaceous materials from tea waste and its removal capacity of indigo carmine present in solution: synthesis, batch and optimization study
Authors: Sikdar Dolanchapa , Goswami Sudipta , Das Papita 
Published: November 2020

AbstractThe present work determines efficiency of domestic food waste like tea waste in removing indigo carmine from synthetic textile wastewater. Carbonaceous material (tea waste) has been employed and it showed removal percentage of indigo carmine at 90% through adsorption process. Carbonaceous material was chemically activated by using modified Hummer’s method and it was observed through Scanning Electron Microscopic image, Fourier Transform Infrared Spectrometer, X-ray diffractometer and Brunauer, Emmett and Teller analysis that revealed that the modified biochar is comparably similar to graphene oxide (GO). Various experimental parameters are evaluated for the removal efficiency of the synthesized adsorbent under the present study. Results of the experiments performed using the GO-like adsorbent synthesized from tea waste confirmed potential efficiency of adsorption of indigo carmine dye from synthetic waste water solution. The adsorption mechanism has been analysed by fitting the experimental data in different adsorption isotherm and kinetic models. The results indicated that the adsorption followed Langmuir isotherm model with maximum uptake of 20 mg g− 1and pseudo second order kinetic model with the best correlation coefficient. The thermodynamic study showed the dye removal to be spontaneous and endothermic.