bluuebunny/crossref_metadata_2025_split huggingface dataset:
Review of Current Practice for Temporomandibular Joint Meniscopexy Surgery
Authors: Sheikh Omar , Ali Madadian Matin , Benning Amanveer 
Published: August 2020

Disc repositioning for temporomandibular joint dysfunction (TMD) is a known and established procedure. Indications for the surgery and outcomes vary. A review of the available literature on the indications, surgical technique, and outcomes of TMJ Meniscopexy as a means of management of temporomandibular joint disease was performed. This was carried out using PubMed, MEDLINE, Scopus, and Google Scholar and was limited to the past 11 years using key medical search terms relevant to the subject area while being consistent with our exclusion criteria. The search yielded a total of 23 articles containing 3 reviews, 6 technical notes, 11 retrospective studies, and 3 prospective studies. Multiple techniques were described in the literature including arthroscopic techniques (n = 4), open suturing techniques (n = 4), mini-anchor techniques (n = 9), and splint-assisted surgery (n = 1). Several variables were used to determine success including both qualitative and quantitative measures determined clinically, through MRI or via patient questionnaire. When considering various combinations of these functional outcomes, all studies showed a significant improvement post-operatively. This demonstrates the success of disc repositioning procedures as an option in certain cases of TMD. Although there is evidence to show improvement in functional outcomes associated with Meniscopexy as a means of TMD management, there remains to be a lack of high-level evidence to further support this.
Physiological, biochemical and genetic responses of Caucasian tea (Camellia sinensis(L.) Kuntze) genotypes under cold and frost stress
Authors: Samarina Lidiia S. , Malyukova Lyudmila S. , Efremov Alexander M. , Simonyan Taisiya A. , Matskiv Alexandra O. , Koninskaya Natalia G. , Rakhmangulov Ruslan S. , Gvasaliya Maya V. , Malyarovskaya Valentina I. , Ryndin Alexey V. , Orlov Yuriy L. , Tong Wei , Hanke Magda-Viola 
Published: August 2020

BackgroundCold and frost are two serious factors limiting the yield of many crops worldwide, including the tea plant(Camellia sinensis(L.) Kuntze). The acclimatization of tea plant from tropical to temperate climate regions resulted in unique germplasm in the North–Western Caucasus with extremely frost-tolerant genotypes.MethodsThe aim of the current research was to evaluate the physiological, biochemical and genetic responses of tolerant and sensitive tea cultivars exposed to cold (0 to +2 °C for 7 days) and frost (−6 to −8 °C for 5 days). Relative water content, cell membranes integrity, pH of the cell sap, water soluble protein, cations, sugars, amino acids were measured under cold and frost. Comparative expression of the following genes ICE1, CBF1, WRKY2, DHN1, DHN2, DHN3, NAC17, NAC26, NAC30, SnRK1.1, SnRK1.2, SnRK1.3, bHLH7, bHLH43, P5CS, LOX1, LOX6, LOX7 were analyzed.ResultsWe found elevated protein (by 3–4 times) and cations (potassium, calcium and magnesium) contents in the leaves of both cultivars under cold and frost treatments. Meanwhile, Leu, Met, Val, Thr, Ser were increased under cold and frost, however tolerant cv. Gruzinskii7 showed earlier accumulation of these amino acids. Out of 18 studied genes, 11 were expressed at greater level in the frost- tolerant cultivar comparing with frost-sensitive one: ICE1, CBF1, WRKY2, DHN2, NAC17, NAC26, SnRK1.1, SnRK1.3, bHLH43, P5CSandLOX6. Positive correlations between certain amino acids namely, Met, Thr, Leu and Ser and studied genes were found. Taken together, the revealed cold responses in Caucasian tea cultivars help better understanding of tea tolerance to low temperature stress and role of revealed metabolites need to be further evaluated in different tea genotypes.
Knowledge about Teratogenic Drugs among Dentists - A Cross-Sectional Survey
Authors: Reshmi B. , Ganapathy Dhanraj , Velayudhan Ashok , Pandurangan Kirankumar 
Published: August 2020

Teratogen is any agent that might interfere with the proper growth and development of the embryo or foetus. Teratogens usually involve radiation, cancer, chemicals, and drugs. Comprehension of teratogenic drugs is of great value to dental practitioners because they handle a wide range of drugs that cause teratogenicity in the care of patients with dental problems during pregnancy. The aim of this survey is to assess the awareness among dentists of teratogenic drugs. The study was conducted among 100 final year dental students and interns in Chennai City. 10 questions eliciting information on the knowledge and understanding of teratogenic drugs were framed and distributed. The responses obtained from the participants were compiled, processed further, and analyzed. 83% of the participants were aware of teratogenic drugs. This study concluded that knowledge about teratogenic drugs is adequate among dental students.
Knowledge, Attitude and Practice of Radiation Protection among Dental Students
Authors: Kuzhalvaimozhi P. , Vadivel Jayanth Kumar 
Published: August 2020

Radiology is one the key cornerstone of investigation in Dentistry. The application of radiology in Dental practice has grown by leaps and bounds in the years gone by. Along with this there is an increase in the number of radiation hazards. The effect of radiation on human beings is very negative. This survey was conducted with the intent of studying the awareness and knowledge of radiation protection in practice. The survey consisted of 10 closed ended questions which were circulated among 100 interns of a dental college. The data collected was entered into microsoft excel and the data was analysed for an association between the gender and the responses using Chi-square analysis. The majority of the participants were females and they believed that radiation causes harm to humans and surprisingly they had also believed that ionised radiation remains suspended in the air after making a radiographic exposure where there was no statistically significant difference between the genders(p>0.05). The questions also assessed whether a clinical examination is advised before a radiographic examination and the majority were of the view it is necessary which was statistically significant(p<0.05). From this study we could infer that students are well aware of the adverse effects of radiation but in terms of safety practices being followed in Dental clinics, there are some pitfalls noticeable.
Awareness of Effect of Ashwagandha (Withania somnifera) on Blood Sugar Levels - A Survey
Authors: Aditya B. Sachin , Priya Jothi , Devi R. Gayatri 
Published: August 2020

Introduction: Ashwagandha (Withania somnifera) is a spice utilized in Ayurveda, the conventional medication of India. Its root has a horsey smell (in Sanskrit, ashva signifies "horse" and gandha signifies "smell") and is said to present the quality and virility of a pony. Different pieces of the plant are utilized, yet the most well-known in supplements is a concentrate of its underlying foundations.
Aim: aim of this study is to compare and assess the awareness among people on the effects of ashwagandha on blood sugar levels.
Materials and Methods: A well structured questionnaire containing 10 questions was circulated among Indian population. The questionnaire has covered basic demographic data such as age, gender, weight, blood pressure and about the awareness of effects of ashwagandha on blood sugar levels.
Conclusion: From the above outcomes, it might be presumed that the Withania somnifera root extract can reduce blood sugar levels. It's mindfulness among individuals must be expanded.
Effect of Two Different Mouth Rinses on S. mutans Counts in Subjects Undergoing Orthodontic Treatment – A Pilot Study
Authors: Abirami S. , Kumar Jain Ravindra , Girija A. S. Smiline 
Published: August 2020

The study is thus aimed to assess and compare the efficacy of Herbostra oil pulling mouthwash with Chlorhexidine mouthwash in reducing plaque accumulation around orthodontic brackets. A total of 20 patients were considered in this study randomly assigned into Group I (experimental group - Herbostra oil pulling mouthwash) and Group II (reference group-0.2% Chlorhexidine mouthwash). The plaque index scores were recorded in each individual at baseline (pre) and after 3 weeks (post). Dental plaque samples were collected around the orthodontic brackets at the cervical region of maxillary upper molars and lower incisors by cotton swabbing method and evaluated for the presence of microflora. Paired sample t-test for Streptococcus mutans count showed that statistically significant difference only within the group II (p=0.000) (Chlorhexidine group) and there was no significant difference within the group I (p=0.103) (Herbostra group). Paired sample t-test for plaque index score shows statistically significant difference within the groups (0.000).Independent t test showed statistically significant difference in the levels of Streptococcus mutans count after 3 weeks between the two groups (p=0.000) with the mean values of (2.230±0.5056), (1.080±0.3458) in group I and group II respectively. From this study we concluded that, even though there was a reduction in plaque scores and S. mutans count with Herbostra oil pulling mouthwash but it was not as effective as Chlorhexidine mouth rinse.
Effect of Streptococcal IgY on Quantity of Streptococcus mutans in High Caries Risk Children
Authors: Mary Ditty J. , Mathew Mebin George 
Published: August 2020

Early childhood caries (ECC) is defined as a condition of one or more of decayed, missing, and filling in teeth (dmft) of children aging less than 71 months or even younger. Prevalence and severity of ECC is still high in some countries. Aim of this study to evaluate the effect of streptococcal IgY on the quantity of Streptococcus mutans in high caries risk children. 20 children aged 3-5 years were selected from the Department of Pedodontics of which 10 children were with high caries experience and 10 were controls who were caries free. Saliva swabs were taken from the occlusal surface of primary second molars and microbial count was counted using mitis salivarius bactaracinagar. High risk caries were given one No decayTM tablet morning and evening for 15 days. Swabs were taken before intervention and than 1 month, 2 months and 3 months post intervention. Streptococcus mutans count was significantly reduced in patients who have taken no decay tablets. Within the limits of the study, we found that streptococcal IgY was able to reduced streptococcus mutans count after 2 months. There was no statistically significant difference in Streptococcus mutans count between high caries risk children and caries free children after 3 months.
Assessment of Nicotine Dependence Using Fagerstrom Test among Patients with Leukoplakia and Oral Submucous Fibrosis
Authors: Prashaanthi N. , Dharman Sreedevi 
Published: August 2020

Tobacco consumption has an influence on the oral mucosa and causes oral malignancy in the due time. On assessing nicotine dependence, appropriate counselling can be given to prevent further progression of the habit. Aim of this study was to assess the nicotine dependence levels among patients with potentially malignant disorders such as leukoplakia and Oral Submucous Fibrosis (OSMF) using fagerstrom test. This study included 140 patients from October 2019 to January 2020 in a dental hospital. Variables such as age, gender, tobacco form and lesion were assessed. Descriptive and chi square statistics were performed. Out of 140 patients, higher prevalence with tobacco usage were among 41-50 years (40%), 94.29% were males and 5.71% were females, 16.43% had low dependency, 52.86% had medium dependency and 30.71% had high dependency. Association between age; nicotine dependency in patients with and without lesion p=0.000(p<0.05), statistically significant. Association between gender and patients with and without lesions p=0.151(p>0.05), statistically not significant. Within the limitations of the present study, males had higher prevalence of tobacco use among 41-50 years. Patients with potentially malignant disorders and smokers without lesion had medium dependence while smokeless tobacco users without lesion had a high dependence.
Awareness on Herbal Mouthwash among Dental Students
Authors: Sivakumar Nathasha , Ganapathy Dhanraj , Pandurangan Kiran Kumar , Velayudhan Ashok 
Published: August 2020

Background: Plaque is the main factor responsible for dental diseases such as dental caries, gingivitis, and periodontitis. Dentists play a vital role in the maintenance of oral hygiene and prescribing mouthwash of plaque control agents is of greater value. This study carried out the awareness of herbal mouthwash among dental students and knows about the herbal mouthwash in detail
Aim: The aim of the study is to assess the awareness of herbal mouthwash among Dental students.
Materials and Methods: This study was conducted by assessing responses to 10 selected questions related to herbal mouthwash through a survey planet among 100 dental students. The results were studied and analyzed.
Results: In this present survey, Awareness of dental students related to herbal mouth wash, only 67% answered only peppermint oil is used in herbal mouth wash. While 9% said it has only cinnamon oil and 3% of them said it has lavender oil and 21% answered it has all of the essential oil mentioned. About 8% of the students said herbal mouthwash only has antibacterial effects. While 12% answered for antimicrobial effect, 6% answered for anti-inflammatory effect and the rest of 24% of the students said it has an antibacterial, antimicrobial, and anti-inflammatory effect.
Conclusion: Awareness on herbal mouthwash for general oral health among dental students is still below the satisfactory level. Awareness of the herbal mouthwash for maintaining good oral hygiene needs to be enhanced among dental students.
Effects of workplaces receiving “accreditation of health workplaces” on breastfeeding promotion, parental leave, and gender equality
Authors: Lin Wei-Ting , Hsieh Chia-Chen , Chang Fong-Ching , Wang Chao-Ling , Lin Chia-I , Chuang Hung-Yi 
Published: August 2020

Abstract

Objectives
Work is often a barrier for women to continue breastfeeding after they have given birth. Breastfeeding support is an important part of workplace health promotion. We investigated the implementation of breastfeeding promotion and gender equality polices in workplaces with the Taiwan Badge of Accredited Healthy Workplace.

Methods
Our samples consisted of 1648 corporations with the badge of Accredited Healthy Workplace issued by the Bureau of Health Promotion from 2007 to 2008. Concomitantly, 2000 corporations without accreditation were randomly selected from the National Business Directory as the control group. Data were collected from self-administered questionnaires. Logistic regression was used to examine the association with breast-feeding promotion and other variables in Taiwanese workplaces.

Results
Members of accredited group of 1089/1648 (66.1%) and the control group of 526/2000 (26.3%) responded to the questionnaire. The accredited companies had more mother-friendly settings, including breastfeeding policies and documents, appropriate breastmilk preserving equipment and settings in the workplace. In the accredited group, breastfeeding rate of mothers returning to work after giving birth was 64.3% in 2008 (1 year after giving birth) and 60.4% in 2009 (1 year after giving birth), while the rate of the control group was 59.1% in 2008 and 51% in 2009.

Conclusion
Accredited corporations are better at breastfeeding support than those of the control group. This might be related to the company size, location, and the implementation of tobacco control and/or occupational health promotion policies, which may increase awareness of healthy workplaces and influence maternal protection positively.
Job insecurity is associated with presenteeism, but not with absenteeism: A study of 19 720 full-time waged workers in South Korea
Authors: Kim Ji-Hwan , Yoon Jaehong , Bahk Jinwook , Kim Seung-Sup 
Published: August 2020

Abstract

Objective
This study examined whether perceived job insecurity was associated with absenteeism and presenteeism, and how these associations varied when the differential cutoff was applied to define absenteeism and presenteeism.

Methods
We analyzed a nationally representative dataset of 19 720 full-time waged workers from the 4th Korean Working Conditions Survey (2014). As an independent variable, perceived job insecurity was assessed. As dependent variables, absenteeism and presenteeism were measured. Seven differential cutoffs (from “1 day” to “7 days”) were used when defining absenteeism and presenteeism. A Poisson regression model with a robust error variance was applied for the analysis.

Results
When “1 day” was cutoff to define absenteeism and presenteeism, job insecurity was not associated with both absenteeism (PR: 1.07, 95% CI: 0.97, 1.16) and presenteeism (PR: 1.05, 95% CI: 1.00, 1.10). When the higher cutoff was used, the association between job insecurity and absenteeism was attenuated and remained statistically nonsignificant. However, statistically significant associations between job insecurity and presenteeism were observed when the differential cutoff was used: “2 days” (PR: 1.07, 95% CI: 1.01, 1.13), “3 days” (PR: 1.14, 95% CI: 1.06, 1.22), “4 days” (PR: 1.15, 95% CI: 1.05, 1.26), “5 days” (PR: 1.18, 95% CI: 1.06, 1.30), “6 days” (PR: 1.17, 95% CI: 1.02, 1.33), and “7 days” (PR: 1.17, 95% CI: 1.02, 1.34).

Conclusion
This study found that perceived job insecurity was associated with presenteeism, but not absenteeism. Furthermore, the association differed by cutoff applied to define presenteeism among full-time waged workers in South Korea.
Bacterial multi‐solute transporters
Authors: Slotboom Dirk J. , Ettema Thijs W. , Nijland Mark , Thangaratnarajah Chancievan 
Published: August 2020

Bacterial membrane proteins of the SbmA/BacA family are multi‐solute transporters that mediate the uptake of structurally diverse hydrophilic molecules, including aminoglycoside antibiotics and antimicrobial peptides. Some family members are full‐length ATP‐binding cassette (ABC) transporters, whereas other members are truncated homologues that lack the nucleotide‐binding domains and thus mediate ATP‐independent transport. A recent cryo‐EM structure of the ABC transporter Rv1819c from Mycobacterium tuberculosis has shed light on the structural basis for multi‐solute transport and has provided insight into the mechanism of transport. Here, we discuss how the protein architecture makes SbmA/BacA family transporters prone to inadvertent import of antibiotics and speculate on the question which physiological processes may benefit from multi‐solute transport.
Adaptive dynamic surface control of stochastic nonstrict‐feedback constrained nonlinear systems with input and state unmodeled dynamics
Authors: Chen Penghao , Zhang Tianping 
Published: August 2020

SummaryIn this paper, the issue of adaptive neural control is discussed for a class of stochastic nonstrict‐feedback constrained nonlinear systems with input and state unmodeled dynamics. A dynamic signal produced by the first‐order auxiliary system is employed to deal with the dynamical uncertain terms. Radial basis function neural networks are used to reconstruct unknown nonlinear continuous functions. With the help of the mean value theorem and Young's inequality, only one learning parameter is adjusted online at recursive each step. Using the hyperbolic tangent function as nonlinear mapping, the output constrained stochastic nonstrict‐feedback system in the presence of unmodeled dynamics is transformed into a novel unconstrained stochastic nonstrict‐feedback system. Based on dynamic surface control technology and the property of Gaussian function, adaptive neural control is developed for the transformed stochastic nonstrict‐feedback system. The output abides by stochastic constraints in probability. By the Lyapunov method, all signals of the closed‐loop control system are proved to be semi‐global uniform ultimate bounded (SGUUB) in probability. The obtained theoretical findings are verified by two numerical examples.
Experimental and Biological Insights from Proteomic Analyses of Extracellular Vesicle Cargos in Normalcy and Disease
Authors: Charest Al 
Published: August 2020

AbstractExtracellular vesicles (EVs) offer a vehicle for diagnostic and therapeutic utility. EVs carry bioactive cargo and an accrued interest in their characterization has emerged. Efforts at identifying EV‐enriched protein or RNA led to a surprising realization that EVs are excessively heterogeneous in nature. This diversity is originally attributed to vesicle sizes but it is becoming evident that different classes of EVs vehiculate distinct molecular cargos. Therefore, one of the current challenges in EV research is their selective isolation in quantities sufficient for efficient downstream analyses. Many protocols have been developed; however, reproducibility between research groups can be difficult to reach and inter‐studies analyses of data from different isolation protocols are unmanageable. Therefore, there is an unmet need to optimize and standardize methods and protocols for the isolation and purification of EVs. This review focuses on the diverse techniques and protocols used over the years to isolate and purify EVs with a special emphasis on their adequacy for proteomics applications. By combining recent advances in specific isolation methods that yield superior quality of EV preparations and mass spectrometry techniques, the field is now prepared for transformative advancements in establishing distinct categorization and cargo identification of subpopulations based on EV surface markers.
Combating Antibiotic‐Resistant Gram‐Negative Bacteria Strains with Tetracycline‐Conjugated Carbon Nanoparticles
Authors: Kim Tak H. , Raiz Asim , Unni Aradhana Devi , Murhekar Shweta , Donose Bogdan C. , Floetenmeyer Matthias , Cock Ian E. , Brown Christopher L. 
Published: August 2020

AbstractNontoxic carbon nanoparticle samples prepared by both bottom‐up and top‐down approaches do not inhibit Gram‐negative bacterial growth, indicating excellent biocompatibilities. However, cell growth inhibitory efficacies increase considerably when the carbon nanoparticles are conjugated with the antibiotic tetracycline. In tetracycline‐resistant bacteria, these efficacies can approach tenfold higher activities when compared to tetracycline alone. No structural abnormality such as membrane disruptions is evident in the tested bacterial strains; this is in contrast with other nanocarbon systems such as graphene oxides, carbon nanotubes, and amine‐functionalized carbon nanoparticles which do exhibit membrane disruptions. In comparison, the tetracycline‐conjugated carbon nanoparticles induce membrane perturbations (but not membrane disruptions), inhibiting bacterial efflux mechanisms. It is proposed that when tetracycline is conjugated to the surface of carbon nanoparticles, it functions to direct the nanoparticles to membrane‐associated tetracycline efflux pumps, thereby blocking and subsequently inhibiting their function. The conjugation between biocompatible carbon nanoparticles and subtherapeutic but well‐established antibiotic molecules may provide hybrid antibiotic assembly strategies resulting in effective multidrug efflux inhibition for combating antibiotic resistance.