bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential Associations of Coping Strategies With Grief and Depression in Young Adults: The Role of Cause of Death and Relationship to the Deceased
Authors: Kokou-Kpolou Cyrille Kossigan , Jumageldinov Askar , Park Sunyoung , Nieuviarts Nicolas , Khales Chama , Cénat Jude Mary 
Published: May 2020

Introduction: The impact of loss by death in young adults has been underinvestigated, although higher rates of traumatic deaths are reported at this developmental stage. This study examined the relative differential consequences of bereavement-related factors for Persistent Complex Bereavement Disorder (PCBD) and depression. In addition, coping strategies predicting the study outcomes were examined as a function of bereavement-related factors.Methods: The study included 580 bereaved young adults with up to 5-year post loss. They were administered a battery of valided tools measuring PCBD symptoms, normal acute grief reactions as measured by the Core Bereavement Items scale, depressive symptoms, coping strategies, and bereavement-related characteristics. Covariance and regression analyses were used.Results: We found that the dimensions of PCBD and depressive symptoms were differentially associated with the bereavement-related factors. More specifically, the death of an immediate family member was associated with higher levels of PCBD-separation distress, whereas the traumatic death of a friend and romantic partner was more associated with PCBD-social and identity disruption. Furthermore, the study revealed differential associations between PCBD severity, depressive symptoms, and coping strategies as functions of bereavement-related factors.Discussion: The study has provided better understanding of clinical manifestations of PCBD as a function of etiologic risk factors. The results clarifying risk and protective factors are especially useful for improving effective bereavement-health counseling interventions among bereaved young adults.
Low Additive Genetic Variation in a Trait Under Selection in Domesticated Rice
Authors: Karavolias Nicholas G , Greenberg Anthony J , Barrero Luz S , Maron Lyza G , Shi Yuxin , Monteverde Eliana , Piñeros Miguel A , McCouch Susan R 
Published: May 2020

AbstractQuantitative traits are important targets of both natural and artificial selection. The genetic architecture of these traits and its change during the adaptive process is thus of fundamental interest. The fate of the additive effects of variants underlying a trait receives particular attention because they constitute the genetic variation component that is transferred from parents to offspring and thus governs the response to selection. While estimation of this component of phenotypic variation is challenging, the increasing availability of dense molecular markers puts it within reach. Inbred plant species offer an additional advantage because phenotypes of genetically identical individuals can be measured in replicate. This makes it possible to estimate marker effects separately from the contribution of the genetic background not captured by genotyped loci. We focused on root growth in domesticated rice, Oryza sativa, under normal and aluminum (Al) stress conditions, a trait under recent selection because it correlates with survival under drought. A dense single nucleotide polymorphism (SNP) map is available for all accessions studied. Taking advantage of this map and a set of Bayesian models, we assessed additive marker effects. While total genetic variation accounted for a large proportion of phenotypic variance, marker effects contributed little information, particularly in the Al-tolerant tropical japonica population of rice. We were unable to identify any loci associated with root growth in this population. Models estimating the aggregate effects of all measured genotypes likewise produced low estimates of marker heritability and were unable to predict total genetic values accurately. Our results support the long-standing conjecture that additive genetic variation is depleted in traits under selection. We further provide evidence that this depletion is due to the prevalence of low-frequency alleles that underlie the trait.
El sistema de salud: barreras para los usuarios con insuficiencia renal crónica
Authors: Ramírez-Perdomo Claudia Andrea , Perdomo-Romero Alix Yaneth , Rodriguez-Vélez María Elena 
Published: May 2020

Objetivo: comprender la experiencia vivida por un grupo de personas con insuficiencia renal crónica que recibieron un trasplante de órgano frente a los servicios de salud y lossignificados del cuidado de la salud realizados por enfermeras y familiares.Materiales y métodos: estudio cualitativo con enfoque fenomenológico-hermenéutico. La muestra se compone de 11 personas con insuficiencia renal crónica trasplantadas, cincocuidadores y cinco enfermeras. Entrevistas recolectadas y grabadas entre diciembre de 2015 y enero de 2017. Para el análisis se empleó el método propuesto por Van Manen.Resultados: uno de los temas que emerge es la experiencia de encontrarse y vivir con insuficiencia renal crónica, del cual se extrae el subtema relacionado con la vivencia en elsistema de salud por parte de las personas enfermas, sus cuidadores y los profesionales de enfermería.Conclusiones: la insuficiencia renal crónica asume un significado complejo y multidimensional para la persona con la enfermedad, sus cuidadores familiares y las enfermeras que asumen el cuidado de este grupo de personas, que los lleva a experimentar el sistema de salud con un efecto adverso que deshumaniza el cuidado de las personas.
‘Please abuse me’
Authors: Li Kunming , Blommaert Jan 
Published: May 2020

In the light of Huizinga’s conceptualisation of play and Bakhtinian carnival theory, this article exemplifies the ludic-carnivalesque qualities of female masochism on China’s social media. Arguably, the joint venture of play and carnival frameworks allows a de-pathological account of female masochism under the male gaze and a reclaiming of the feminist agenda through the critical reading of abusive texts in the pan-entertaining digital era. Thus, the study fills a gap regarding non-sexual female masochistic pleasure in the literature of feminist studies. The article has found billingsgate language, or the language of marketplace, a fertile ground to investigate patriarchy and objectification. It contends that billingsgate language, which hails a ludic-carnivalesque exposure of present patriarchal biases against women and imbalanced gender power relations, is pregnant with a power of deconstruction that overturns present social orders in favour of gender equalities.
Projecting masculinities or breaking sociolinguistic norms? The role of women’s representation in students’ profane language use
Authors: Diabah Grace 
Published: May 2020

This paper explores how students from University of Ghana’s Commonwealth Hall (the only all-male hall of residence) project diverse masculine identities through how they represent women in their use of profanity and other uncouth linguistic forms. Data were collected from recorded profane songs, observations from various case studies of the use of insults and profane expressions and interviews with users of these expressions. The data generally present a picture of sexual and verbal abuse as ‘ideal’ ways of showing male dominance and power over women. These abuses are valued by the students, even though they are not expected practices in Ghanaian society. The paper concludes that although some students claim they use this language ‘just for fun’, disguising it as harmless only makes it easy to explore obsessions without a sense of guilt. If not properly checked, such obsessions may find expression in how women are treated.
A Deregulated Stress Response Underlies Distinct INF2-Associated Disease Profiles
Authors: Bayraktar Samet , Nehrig Julian , Menis Ekaterina , Karli Kevser , Janning Annette , Struk Thaddäus , Halbritter Jan , Michgehl Ulf , Krahn Michael P. , Schuberth Christian E. , Pavenstädt Hermann , Wedlich-Söldner Roland 
Published: May 2020

Significance Statement
Inverted formin 2 (INF2) is the key regulator of a stress response—calcium-mediated actin reset, or CaAR—that reorganizes the actin cytoskeleton of mammalian cells in response to calcium influx. INF2 has been linked to the podocytic kidney disease focal segemental glomerulosclerosis (FSGS) and to cases of the neurologic disorder Charcot–Marie–Tooth disease that are accompanied by FSGS. The authors show that >50 disease-associated INF2 variants lead to deregulation of CaAR in cell lines, in Drosophila nephrocytes, and in cells from patient cells with these disorders. Their findings suggest that CaAR can be used as a sensitive assay for INF2 function and for robust evaluation of disease-linked variants of this formin. This work also highlights the use of quantitative cellular assays in assessing effects of disease-associated mutations to better understand complex disease phenotypes.

Background
Monogenic diseases provide favorable opportunities to elucidate the molecular mechanisms of disease progression and improve medical diagnostics. However, the complex interplay between genetic and environmental factors in disease etiologies makes it difficult to discern the mechanistic links between different alleles of a single locus and their associated pathophysiologies. Inverted formin 2 (INF2), an actin regulator, mediates a stress response—calcium mediated actin reset, or CaAR—that reorganizes the actin cytoskeleton of mammalian cells in response to calcium influx. It has been linked to the podocytic kidney disease focal segemental glomerulosclerosis (FSGS), as well as to cases of the neurologic disorder Charcot–Marie–Tooth disease that are accompanied by nephropathy, mostly FSGS.

Methods
We used a combination of quantitative live cell imaging and validation in primary patient cells and Drosophila nephrocytes to systematically characterize a large panel of >50 autosomal dominant INF2 mutants that have been reported to cause either FSGS alone or with Charcot–Marie–Tooth disease.

Results
We found that INF2 mutations lead to deregulated activation of formin and a constitutive stress response in cultured cells, primary patient cells, and Drosophila nephrocytes. We were able to clearly distinguish between INF2 mutations that were linked exclusively to FSGS from those that caused a combination of FSGS and Charcot–Marie–Tooth disease. Furthermore, we were able to identify distinct subsets of INF2 variants that exhibit varying degrees of activation.

Conclusions
Our results suggest that CaAR can be used as a sensitive assay for INF2 function and for robust evaluation of diseased-linked variants of formin. More broadly, these findings indicate that cellular profiling of disease-associated mutations has potential to contribute substantially to sequence-based phenotype predictions.
THREAT TO THE QUALITY OF EDUCATION CAUSED BY THE TRANSFER OF AN OFFICIAL IN THE EDUCATION INSTITUTION OF THE MINISTRY OF THE INTERIOR
Authors: Indriksons Alens 
Published: May 2020

The leader of organization, his competence and the policies he pursues with regard to the management of the organization play an important role in the achievement of the goals of any institution, including educational. The leader has a direct influence on the performance of employees in order to achieve the goals of the organization. In the Ministry of the Interior, however, the officials responsible for achieving the goals of educational institution are appointed in the interest of the service.The aim of the research is to determine the impact of the transfer of officials in the interests of the service on the achievement of educational objectives in the professional training of border guards.The study was conducted in the State Border Guard College using scientific, pedagogical and psychological literature analysis and evaluation and document analysis research method. As a result of the study the author brought forward conclusions that the biggest threats to the quality of education and to the achievement of the goals of educational institution in the system of the Ministry of the Interior is transfer of official in the interests of the service ignoring their competence in educational knowledge’s. To avoid threats to the quality of education, proposals were developed.
SELF-IMPOSED ETHICAL GUIDELINES FOR AI IN EDUCATION
Authors: Leimanis Anri 
Published: May 2020

Advances in Artificial Intelligence (AI) applications to education have encouraged an extensive global discourse on the underlying ethical principles and values. In a response numerous research institutions, companies, public agencies and non-governmental entities around the globe have published their own guidelines and / or policies for ethical AI. Even though the aim for most of the guidelines is to maximize the benefits that AI delivers to education, the policies differ significantly in content as well as application. In order to facilitate further discussion about the ethical principles, responsibilities of educational institutions using AI and to potentially arrive at a consensus concerning safe and desirable uses of AI in education, this paper performs an evaluation of the self-imposed AI ethics guidelines identifying the common principles and approaches as well as drawbacks limiting the practical and legal application of the policies.
PEDAGOGIC DIAGNOSTIC METHODS OF JUVENILE CONVICTS SOCIAL HEALTH: EXPERIMENTAL STUDY
Authors: Ganishina Irina , Podnebesnaya Ella , Mamedova Albina , Tyugaeva Nina , Tkachenko Nikolay , Ovsyannikova Marina 
Published: May 2020

Convicts social health is regarded by the authors of the article as the state of social welfare including the ability to support the socially healthy relationships in the society. To diagnose this state of ability among the juvenile convicts serving sentences in the correctional colonies is of special importance. According to the experimental study there is not enough work done to develop social health among juvenile convicts in the places where the imprisoned are stayed. The hypothesis of the investigation is the assumption that to form the social health among convicted male minors in the juvenile correctional facility will be more successful if they participate in the project “Book is the source of new life and the way to rehabilitation.” To diagnose the state of social health of juvenile convicts the following methods and techniques have been used, they are watching, talking, summative assessment, formative assessment, testing, The Test of Viability by D.A. Leontyev, The Questionnaire: Health, Activity, Mood (by V.A. Doskin, N.A. Lavrentyeva, V.B. Sharay, M.P. Miroshnikov); Success Stimuli and Failure Fear methods by A.A. Rean. The summative assessment procedure was held in March 2019, the formative assessment experiment had been conducted for 3 months (from April till June 2019). The summative assessment has shown that juvenile convicts have weak viability, reduced level of well-being, and activity, and mood as well; there is a low level of success stimuli and high level of failure fear. The results of formative assessment have shown that the participation in the Project helps to form viability, activity, cheering up, decreasing of failure fear, increasing of success motivation; and it assists conforming social health of juvenile convicts as a whole.
MEDIATING ROLE OF DISSOCIATION SYMPTOMS BETWEEN ADOLESCENT COMPULSIVE INTERNET USE ACROSS TIME
Authors: Miltuze Anika , Sebre Sandra Beatrice 
Published: May 2020

The aim of this study was to examine adolescent compulsive internet use (CIU) across a one-year period, to examine associations with symptoms of depression, anxiety and dissociation, as well as to analyze the potential mediating effect of dissociation symptoms. Previous studies have indicated that dissociation might serve as a coping strategy and/or as a consequence of problematic internet use. Participating in the study were 80 adolescents (39 girls and 41 boys), ages from 12 to 18 (mean age 14.90 years) at the time of the first measurement. At Time 1 and one year later at Time 2 measurement points the participants completed the Trauma Symptom Checklist (Briere, 1995) and items from the Compulsive Internet Use Scale (Meerkert, VanDen Eijnden, Vermulst, & Garretsen, 2009). Correlation analyses showed associations between CIU and the adolescents’ ratings of anxiety, depression and dissociation at Time 1 and Time 2. Mediation analysis indicated partial mediation of dissociation symptoms between CIU at Time 1 and Time 2. A comparison of these relationships across time provides opportunity to discuss possible directions of causality and implications of bidirectionality between dissociative tendencies and adolescent prolonged, compulsive internet use.
Organik Gıdalara Yönelik Tüketici Yaklaşımları ve Pazarlama İletişimi Önerileri
Authors: KÖSE Şirin Gizem , KIRCOVA İbrahim 
Published: May 2020

Organik gıda, hem uygulayıcıların hem de akademinin son yıllarda daha fazla ilgisini çekmektedir. Ayrıca, sürdürülebilirliğe katkı sağlayan yönüyle organik gıda tüketimi, hükümetler tarafından da teşvik edilmektedir. Organik gıda üzerine yapılan çalışmaların önemli bir kısmı, organik gıda satın alma sebeplerini incelemektedir. Bununla birlikte, organik gıda literatürü çoğunlukla Türkiye’ye kıyasla daha büyük organik gıda pazarının olduğu ve pazarın olgunlaştığı yurtdışından örneklemler içermektedir. Bu çalışmanın amacı, Türkiye’de organik gıda satın almanın önündeki engellerin tüketici bakış açısıyla incelenmesi, ayrıca tüketicilerin organik gıdaya yönelik içgörüleri aracılığıyla organik gıda markalarının pazarlama iletişimi çalışmalarına ışık tutulmasıdır. Bu amaç doğrultusunda veri elde etmede nitel araştırma yöntemlerinden derinlemesine mülakat tekniği kullanılmıştır. Çalışma sonuçlarına göre organik gıda ile tüketici arasındaki temel engeller yoğunluk ve kişilik unsurlarından oluşan bireysel unsurlar; üreticiye, dağıtıcıya ve menşei ülkeye güvenmeme; dağıtım eksikliği; çevrenin algısı; aşırı doğallık; fiyat ve farklılık algısının oluşmamasıdır. Bununla birlikte, tüketicilerin organik gıda hakkında bilgi edinme kaynakları, organik gıdanın tüketicilere çağrıştırdıkları, tüketiciye bir ürünün organik olduğunu işaret eden unsurlar, organik gıda tüketen kişilerin profilini tüketicilerin nasıl gördüğü de incelenmiştir. Elde edilen bulgular doğrultusunda, organik gıda sektöründe faaliyet gösteren markalara pazarlama iletişimi çabaları çerçevesinde öneriler sunulmaktadır.
Relationship of chronic rhinosinusitis with dental malocclusion: a prospective study
Authors: Sonone Jayant K. , Tikar Gaurav S. , Thakare Pallavi G. , Meshram Sushil N. 
Published: May 2020

<p class="abstract"><strong>Background:</strong> The purpose of this study was to find the effect of chronic rhinosinusitis on dental malocclusion. A malocclusion is defined as an irregularity of the teeth or a mal relationship of the dental arches beyond the range of what is accepted as normal. Malocclusion may not be life-threatening, but it is an important public health issue as it compromises the health of oral tissues and also can lead to psychological and social problems. There are numerous studies in the literature about prevalence of the dental malocclusion but there is no study regarding association of CRS and malocclusion. Several factors related to malocclusion, such as anterior crowding, midline malalignment, and facial asymmetry, have strong effects on the perception of facial aesthetics, which influence the psychological development and in turn, influence social acceptance and self‑perception.</p><p class="abstract"><strong>Methods:</strong> This was a prospective cross-sectional observational study was conducted from September 2015 to August 2017 and 57 patients with diagnosis of having chronic sinusitis, were evaluated for dental occlusion. Malocclusion is then classified by angle’s classification. </p><p class="abstract"><strong>Results:</strong> Most patients of chronic rhinosinusitis had dental malocclusion in grade II, followed by grade I, then grade III.</p><p class="abstract"><strong>Conclusions:</strong> While treating the patients of CRS one must keep in mind that he may have class II malocclusion which may cause gum disease, poor oral hygiene, impaired speech, mastication and aesthetics of face and need orthodontics management as well.</p>
Profile of head and neck neoplasms at a tertiary care centre in North India: two years pilot study (2018-2019)
Authors: Munjal Manish , Rishi Porshia , Tuli Nitika , Singh Harjinder , Talwar Shivam , Sharma Salony , Munjal Shubham 
Published: May 2020

<p class="abstract"><strong>Background:</strong> In India 53,251 New Head and neck cancer cases are diagnosed every year. Oral cancer is the predominant subsite among both benign and malignant lesions.</p><p class="abstract"><strong>Methods:</strong> A retrospective study of cases with head and neck neoplastic lesions was conducted in department of otolaryngology, head and neck surgery, Dayanand Medical College and Hospital Ludhiana during for a period of 2 years (January 2018 to December 2019). Demographic, gender profile of the patients was studied. </p><p class="abstract"><strong>Results:</strong> Incidence of oral cancer was 21.5% followed by salivary glands 18.9%. among head and neck neoplasms over a period of 2 years (January 2018 to December 2019). The overall male to female ratio was 1:1.25, among benign was 1:1 and among malignant was 1:1.3.</p><p class="abstract"><strong>Conclusions:</strong> Commonest subsite of benign lesions was - oral cavity followed by salivary glands and larynx. Most common malignant subsite was oral cavity followed by larynx and thyroid. Male patients outnumbered the female. Mean age of presentation varied according to subsite.</p>
Aparelhos celulares e a detecção precoce do câncer de mama: possibilidade de educação em saúde para mulheres
Authors: Bilotti Carolina Correia , Oliveira Maria Gabriela Bernardo , Tavares Mariane Frez , Macuch Regiane Da Silva , Bernuci Marcelo Picinin 
Published: May 2020

O estudo buscou analisar a possibilidade da incorporação dos aparelhos celulares nas estratégias de educação em saúde relacionada ao câncer de mama de mulheres atendidas pelas equipes da Estratégia de Saúde da Família. Estudo descritivo realizado com mulheres com idade igual ou superior a 40 anos residentes em Maringá, Paraná, em 2016. Os dados foram coletados durante visita domiciliar por meio da aplicação de questionário semiestruturado composto de questões relativas ao perfil de uso de aparelhos celulares e internet, bem como do acesso a informações sobre saúde. Pesquisou-se 259 mulheres, das quais 95,75% declarou utilizar aparelhos celulares; 67,18% utiliza há mais de três anos; 69,11% utiliza para realizar ligações telefônicas e 28,96% utiliza para acessar internet. Quanto ao uso de internet, 45,17% afirmou utilizar internet paga, 33,59% utilizam para pesquisar; 31,27% para acessar redes sociais e 8,11% para acessar portais do governo. Para receber informação sobre saúde, 50,19% prefere panfletos; 40,93% prefere aparelhos celulares e 25,48% prefere palestras. A incorporação dos aparelhos celulares nas estratégias de educação em saúde direcionada ao câncer de mama mostra-se viável, porém, faz-se necessário considerar limitações de usabilidade e acesso à internet.
Carcinoma microinvasor de cuello uterino
Authors: Botero Uribe Jaime , Uribe Duque Jaime , Londoño Juan Luis 
Published: May 2020

El presente estudio constituye una revisión retrospectiva de los casos de carcinoma microinvasor de cuello uterino que se han presentado en el servicio de Oncología del Hospital Universitario San Vicente de Paúl de Medellín desde el 1o. de enero de 1970 hasta el 31 de diciembre de 1984 y busca encontrar orientaciones que nos permitan adoptar para el futuro una modalidad de tratamiento que a la vez que ofrezca la máxima seguridad a las pacientes, utilice en forma óptima los recursos médicos y permita un seguimiento adecuado para determinar la eficacia a largo plazo de las medidas terapéuticas.