bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prosthetic Rehabilitation of Amputated Fingers Using Thimble Prosthesis: A Novel Methodology
Authors: Dewan Sumedha , Kalra Tarun , Kumar Manjit , Bansal Ajay 
Published: January 2020

AbstractAny kind of deformity or injury to the finger or hand is one of the most encountered type of injuries, which may cause psychological and emotional disturbance to the patient. The prosthetic rehabilitation of the amputed part of the finger supports the patient emotionally as well as physically and also has a role in making the patient socially more acceptable. This case report highlights on a simple technique for fabricating a thimble prosthesis using silicone elastomers.
Climate crisis, health equity, and democratic governance: the need to act together
Authors: Krieger Nancy 
Published: January 2020

AbstractOn Friday, 20 September 2019, over 4 million people worldwide participated in the youth-led Global Climate Strike. Emphasizing the dire impacts of the climate crisis on people’s health, planetary health, and health equity, participants called for politicians and those with power to listen to the scientists and to the evidence. But who are these politicians and what is the evidence regarding to whom they listen? In the United States (US), critical research documents how the public’s will is being subverted—and people and planetary health are being harmed—via changes to the ‘rules of the game’ that affect democratic governance. Health professionals, organizations, and institutions should encourage civic engagement—for themselves, their staff, members, and study participants—regarding: voter registration; being counted in the 2020 Census; countering partisan gerrymandering; and helping to build strong coalitions addressing profound links between climate change, health equity, and democratic governance.
Cops5 safeguards genomic stability of embryonic stem cells through regulating cellular metabolism and DNA repair
Authors: Li Peng , Gao Lulu , Cui Tongxi , Zhang Weiyu , Zhao Zixin , Chen Lingyi 
Published: January 2020

Significance
Genome integrity is required for clinical applications of pluripotent stem cells. Two major strategies, maintaining low levels of reactive oxygen species (ROS) and high DNA damage repair (DDR) activities, are applied by embryonic stem cells (ESCs) to secure their genomic stability. Here, we demonstrate the pivotal role of Cops5 in safeguarding genome integrity of ESCs. Through regulating the autophagic degradation of Mtch2, Cops5 suppresses oxidative phosphorylation and ROS production, thereby reducing endogenous DNA damage. Meanwhile, Cops5 is also involved in maintaining high DDR activities, including nucleotide excision repair, nonhomologous end joining, and homologous recombination, in ESCs.
Neuroprotective effect of Annona muricata-derived polysaccharides in neuronal HT22 cell damage induced by hydrogen peroxide
Authors: Kim Woo Sik , Kim Yi-Eun , Cho Eun-Ji , Byun Eui-Baek , Park Woo Yong , Song Ha-Yeon , Kim Kwangwook , Park Sang-Hyun , Byun Eui-Hong 
Published: January 2020

Abstract

Crude extracts and phytochemical compounds derived from Annona muricata leaves have been demonstrated to exert neuroprotective effects. However, the neuroprotective effects of Annona muricata leaves-derived polysaccharide extracts (ALPs) have not been investigated. ALP treatment was shown to induce concentration-dependent antioxidant activity in HT22 cells, and to increase cell viability in H2O2-treated HT22 cells. These effects were correlated with a decrease in major components of oxidation, including: Ca2+, ROS, and malondialdehyde (MDA). Mediators of the intracellular response to oxidation, including Bax, cytochrome c, and cleaved caspases-3, -8, -9, MAPKs, and NF-κB, were positively influenced by ALP treatment under conditions of H2O2-mediated oxidative stress. In addition, ALP restored the expression of superoxide dismutase (SOD) and associated signaling pathways (PARP, PI3K/AKT and Nrf2-mediated HO-1/NQO-1) following H2O2 treatment. These results provide new pharmacological evidence that ALP facilitates neuroprotection via prevention of neuronal oxidative stress and promotion of cell survival signaling pathways.

Abbreviations
ABTS: 2,2ʹ-azino-bis-(3-ethylbenzothiazoline-6-sulfonicacid); AD: Alzheimer’s disease; ALP: polysaccharide extracts isolated from Annona muricata leaves; ARE: antioxidant response element; DPPH: 1,1-diphenyl-picrylhydrazyl; DCFH-DA: 2ʹ,7ʹ-dichlorofluorescin diacetate; ECL: electrochemiluminescence; ERK: extracellular regulated kinase; FBS: Fetal bovine serum; FITC: fluorescein isothiocyanate; FRAP: ferric reducing antioxidant power; HO-1: Heme oxygenase-1; JNK: c-jun N-terminal kinase; MAPKs: mitogen-activated protein kinases; MDA: malondialdehyde; MMP: mitochondrial membrane potential; MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide; NQO1: NAD(P)H:quinine oxidoreductase 1, Nrf2: nuclear factor-E2-related factor 2; PD: parkinson’s disease; PI3K: phosphatidylinositol-3kinase; PVDF: polyvinylidene difluoride; ROS: reactive oxygen species; SOD: Superoxidedismutase; TPTZ: tripydyltriazine
Symbiotic riboflavin degradation by Microbacterium and Nocardioides bacteria
Authors: Kanazawa Hiroshi , Ozaki Sayoko , Doi Yuki , Masuo Shunsuke , Takaya Naoki 
Published: January 2020

Abstract
Unlike its biosynthetic mechanisms and physiological function, current understanding of riboflavin degradation in soil is limited to a few bacteria that decompose it to lumichrome. Here, we isolated six Microbacterium and three Nocardioides strains. These strains utilized riboflavin and lumichrome, respectively, as carbon sources. Among these strains, we identified Microbacterium paraoxydans R16 (R16) and Nocardioides nitrophenolicus L16 (L16), which were isolated form the same enrichment culture. Co-cultured R16 and L16 reconstituted a riboflavin-degrading interspecies consortium, in which the R16 strain degraded riboflavin to lumichrome and ᴅ-ribose. The L16 strain utilized the lumichrome as a carbon source, indicating that R16 is required for L16 to grow in the consortium. Notably, rates of riboflavin degradation and growth were increased in co-cultured, compared with monocultured R16 cells. These results indicated that a beneficial symbiotic interaction between M. paraoxydans R16 and N. nitrophenolicus L16 results in the ability to degrade riboflavin.
Applying the Theory of Planned Behavior in Functional Food Purchasing: a Young Consumers Perception
Authors: Bakti I G M Y , Sumaedi S , Astrini N J , Rakhmawati T , Yarmen M , Damayanti S 
Published: January 2020

Abstract
The 4.0 industrial era has impact not only on the industrial sector but also on the changes of people’s lifestyle, including the healthy lifestyle changes. More specifically, one of the impacts of the 4.0 industrial era is the growth of functional food industry. This research aims to analyze the effect of attitude, subjective norm, and perceived behavioral control on young consumers’ purchase intention on functional food. This research focused on young consumers because they are susceptible to consume a food that can cause non-communicable diseases. This study used a quantitative approach. A survey was used to collect data. Questionnaires were spread in a university in South Tangerang. This study obtained 123 students that participated in the survey. Multiple regressions analysis was performed to test the conceptual model and the proposed hypotheses. The findings showed that attitude and subjective norm influence the purchase intention of the young consumers to buy functional foods. In the other hand, this research also revealed that perceived behavioural control has no significant impact on repurchase intention.
Increasing performance of straight pattern of rubber tyre on asphalt track due to sulfur composition
Authors: Purboputro P I , Darmawan A S , Hendrawan M A 
Published: January 2020

Abstract
The motion of a ground vehicle is primarily determined by friction force transferred from road via tires. Therefore, the effect of the compound composition on the hardness and wear resistance is investigated. The grip coefficients on the track in wet and dry conditions are also investigated. In this research, the three combinations of black carbon and sulfur composition namely compound 1, compound 2 and compound 3 are provided. The hardness, wear resistance and grip coefficient are then tested. The results of the tests are also compared to the existing compound material which is already on the market. The shore A hardness of compound 1, compound 2 and compound 3 are 75, 75, and 77 respectively. The wear rate of compound 1, compound 2 and compound 3 in dry asphalt condition are 19.49 mm3/sec, 18.64 mm3/sec and 13.42 mm3/sec respectively. The wear rate of compound 1, compound 2 and compound 3 in wet asphalt condition are 6.457 mm3/sec, 5.933 mm3/sec and 4.133 mm3/sec respectively. The grip coefficient of compound 1, compound 2 and compound 3 in dry asphalt condition are 0.756, 0.751, and 0.725 respectively. The grip coefficient of compound 1, compound 2 and compound 3 in wet asphalt condition are 0.702, 0.693, and 0.685 respectively. The compound material already on the market has shore A hardness of 71, wear rate in dry asphalt condition of 11.40 mm3/sec, wear rate in wet asphalt condition of 2.800 mm3/sec, grip coefficient in dry asphalt condition of 0.773 and grip coefficient in wet asphalt condition of 0.727. The shore A hardness and wear rate of compound 1, compound 2 and compound 3 are higher than the shore A hardness and wear rate of the compound material already on the market. While the grip coefficient of compound 1, compound 2 and compound 3 are lower than the grip coefficient of the compound material already on the market.
Performance Improvement in Aerospace Production Through Lean Manufacturing Implementation
Authors: Zahra A Az , Indrawati S , Sulistio J 
Published: January 2020

Abstract
The high demand in aerospace industry require on going improvement to meet its costumer. Prototyping is a form of effort to ensure the quality of airplanes. However, several problems rose in this phase but two of them are significant in disrupting the production system. They are the spare parts tardiness and unnecessary motion leading a high lead time. The objective of this article is to develop lean action plan to reduce lead time in airplane prototyping. The method applied in this paper is divided into three major phases. Firstly, evaluate current system performance using Value Stream Mapping (VSM). Secondly, determine the dominant waste by cooperating waste finding checklist. Finally, develop a lean action plan. Most waste occurred in production activities. Waste of motion is the highest among other waste with the score of 44 followed by waiting with the score of 24. The third highest waste is excess processing with the score of 2. The causes of these wastes are lack of facilities such as machines and tools and inefficient operators in picking and mixing sealant. The lean action plans are to add machines and tools for labelling, adding sealant room and to change the production plant lay out. By doing so, the lead time can be reduced up to 0,25 hours.
A Prototype of Effective Online Teaching Tools with Adaptive Navigation Support
Authors: Hamzah A 
Published: January 2020

Abstract
This paper proposes a prototype of educational system based on adaptive navigation support to help teacher manage their courses online. In a university context, a teacher can have many courses in one semester. The courses consists of several topics with several material and assignments on it. In a such circumstances, a teacher must prepare the topic’s material before they can go to the class. This situation can cause the teacher to overwhelmingly getting busy to identify which courses they want to focus on and which one they do not. Therefore, they need a tools as an aid to choose which courses they should focus on. In this study, a prototype has been built based on adaptive navigation approach to help teacher overcome the situation. Link hiding techniques were used as a mechanism to help user focus on one task at a time.
Sustainable risk mitigation in manufacturing company
Authors: Kusrini E , Handayani S 
Published: January 2020

Abstract
Companies that are not aware of any risk events and sources of risk that occur in the company, will not be able to formulate an appropriate strategy in mitigating risk. This research aims to identify, measure and plan risk mitigation strategies related to sustainable risk. Sustainable risk is related to risks from environmental, economic and social aspects. This research takes a case study in one of the manufacturing companies in Indonesia. This study uses the Failure Mode and Effect Analysis (FMEA) method to identify events and sources of risk and the House of Risk (HOR) to analyze and design risk mitigation. This research identified 14 risk events and 39 sources of risk that occurred in the company. By using the HOR method, 15 priority sustainability risk mitigation actions were obtained.
Study of Energy Saving Performance Contracts Application for Electrical Energy Efficiency in Industrial and Commercial Sectors
Authors: Sanvia F S , Garniwa I , Alvianingsih G , Aryani D R 
Published: January 2020

Abstract
Industrial and Commercial sectors are the largest energy consumption. Building sector is one of the biggest energy consumptions, especially in Industrial and commercial devices, like air conditioning systems, lighting systems, and building transportation systems. Energy Saving Performance Contract (ESPC) could be an alternative to support implementation of energy efficiency in building sector up to 10-30%. This study investigates about application of ESPC for air conditioning system retrofit in Industrial and Commercial building, namely Chiller. Chiller retrofit could produce energy efficiency 210 MWh/year or reduce up to 30% of energy consumption with a 5-year payback period investment. This study can be broadened to develop application of ESPC in Indonesia.
Machine learning approach to air traffic control skill based on mastery theory of aerodrome control procedures, self-concept and practice drills
Authors: Hutabarat Liber Tommy , Sunardy  , Sysvia Tiara , Dwiyanto  , Sinambela Marzuki 
Published: January 2020

Abstract
The objectives of the research were to discover the correlation of mastery theory of aerodrome control procedures toward the skill of air traffic control, self-concept toward the skill of air traffic control, frequency of drills toward the skill of air traffic control and correlation of mastery theory of aerodrome control procedures, self-concept and frequency of drills toward the skill of air traffic control. The population consisted of 105 students and 50 students were taken as the sample through cluster random sampling technique. The results of the research concluded, there was a significantly positive correlation between mastery theory of aerodrome control procedures and skill of air traffic control as shown by coefficient correlation 0.6648, there was a significant positive correlation between self-concept and skill of air traffic control as shown by coefficient correlation 0.5825, there was significant positive correlation between frequency of drills and skill of air traffic control as shown by coefficient correlation 0.4159 and there was significant positive correlation of mastery theory of aerodrome control procedures, self-concept, frequency of drills toward the skill of air traffic control as shown by multiple coefficient correlation 0.740. Determination coefficient of multiple correlations was 0.5478 or 54.78% showed that mastery theory of aerodrome control procedures, self-concept, frequency of drills gave impact on skill of air traffic control.
Energy consumption prediction for electric rickshaw based on load variance
Authors: Siagian Parulian , Napitupulu Richard , Sianturi Libianko , Barus Rohancen P , Mendrofa Omesh , Siregar Wandro , Sinambela Marzuki 
Published: January 2020

Abstract
Electrical Rikshaw forecasting is usually a univariate time series forecasting problem. The recent increase in load variance of electric rickshaw has lead to large available datasets. In this case, we use the machine learning approach based on Long Short Term Memory (LSTM) and Support Vector Machine (SVM). The accurate energy consumption of electric Rickshaw forecasting is depended to train and test real dataset. The time series of electric Rickshaw observed in Mechanical Labs of Universitas HKBP Nomensen, Medan, Indonesia. The main aim of this paper to generate the observation of energy consumption from the electric rickshaw and look for accuracy of electrical load in the substation.
LTE soft handover based on hysteresis and threshold combination
Authors: Pinem Maksum , Rifki Mhd Ikhsan , Sinulingga Emerson P. , Suherman S. 
Published: January 2020

Abstract
This paper proposes the combination of hysteresis and threshold based soft handover in the long-term evolution (LTE) network and presents the performance evaluation. As the simulation conducted, the observations of the generated data show that the threshold margin of -115 dBm with hysteresis margin 24 produces the highest active set, achieving 2.082. The higher the active set value results the lower the outage probability. Outage probability for threshold value of -115 dBm occurs at distance 611 m, reaching only 2.1x10−7.
Emergency patient health service simulation as a supporter of smart health care
Authors: Pardede A M H , Novriyenni N , Kadim L A N 
Published: January 2020

Abstract
Providing health services for patient requests obtained from smart devices installed in each patient can be done if the service center has adequate resources and there are no criteria for emergency patients, but this will be different if in real life an emergency service request occurs. Providing emergency services to hospitals is growing, especially with the introduction and evolution of triage systems by giving priority services to patients based on their level of urgency. Providing services to emergency patients must be a priority in service delivery, because it can be ascertained that this emergency request is closely related to the safety of the patient’s life, such as an accident or sudden onset of disease. Service simulations in patients are carried out using Simulink, by limiting the availability of all the resources in the service center, and providing real life simulation events for 56 emergency patients, and the simulation concludes that priority queuing systems can serve all patient requests and perform as quickly as possible.
Preparation of doped microstructure diffusing film by photocuring micro-imprint
Authors: Jiajia Wang , Jianyun He , Changsong Zhao , Pengcheng Xie , Jinge Tong 
Published: January 2020

Abstract
In this paper, the process of preparing of doped diffusion film by ultraviolet curing micro-embossing was studied. The preparation method of microstructure diffusion film by photo-curing micro-embossing is different from the traditional methods. The effect of irradiation time on the apparent quality and the effect of the percentage of light diffusing agent on the optical properties and tensile properties of the diffusion film were investigated. The results shown that under the condition of 365 nm ultraviolet light wavelength and a light intensity of 800 mW/cm2 , the apparent quality of the diffusion film was good. When the irradiation time was 6 s; and the content of the diffusing agent was 30%, the optical performance was relatively good; the larger the content of the light diffusing agent, the smaller the tensile strength of the diffusing film.
In vitro degradation behavior of as-cast Mg-3Zn-1Ca-0.5 Sr alloy
Authors: Liu Hening , Zhang Kui , Yuan Jiawei , Li Yongjun , Li Xinggang , Ma Minglong , Shi Guoliang , Wang Kaikun 
Published: January 2020

Abstract
Recent advancements in bone implant materials have led to the development of various alloys. In this study, the degradation behavior of the as-cast Mg-3 wt% Zn-1 wt% Ca-0.5 wt% Sr alloy in vitro was investigated using x-ray diffraction (XRD), scanning Kelvin probe force microscopy (SKPFM), and scanning electron microscopy (SEM). Our results demonstrated that the alloy microstructure was composed of α-Mg, a Ca2Mg6Zn3 phase, and a Mg17Sr2 phase. The Ca2Mg6Zn3 phase, which had the smallest absolute potential, was shown to have cathodic protection, while the α-Mg, which had the largest absolute potential, was shown to prefer corrosion. The in vitro corrosion products of the as-cast alloy were Mg(OH)2, a Ca-P compound, and HA. At the beginning of the corrosion, the hydrogen evolution rate of the alloy was fast due to the thin corrosion product layer. With the extension of the corrosion time, the corrosion layer thickened and the hydrogen evolution rate slowed down and stabilized to 1.25 × 10−5 mol cm−2 · h . Due to the high concentration of Ca and Mg ions near the second phase, HA was quickly deposited and an ion exchange channel between the solution and the alloy was formed, making it easier for the Mg, Ca, and Sr ions to enter the solution and promote the formation of HA. The hysteresis effect of Sr element was found, that is, Sr ions were released into the solution after etching for a period of time, which promoted the formation of HA and HA-containing Sr (Sr/HA).
Relationship between thermophysical properties and structure of CMAS glass melts based on chromium slag
Authors: Deng Leibo , Yun Fei , Jia Ruidong , Li Hao , Ren Da , Zhang Xuefeng , Jia Xiaolin 
Published: January 2020

Abstract
In an attempt to determine the relationship among the network structure, viscosity, electrical conductivity, surface tension, and density of chromium-containing glass melts, the variation in glass melt thermophysical properties of the CaO–MgO–Al2O3–SiO2 quaternary system were investigated by comprehensive physical property analysis and Raman spectroscopy. The results demonstrated that the network structural units Q

n
(n = 0, 1, 2, 3) coexisted in the glass melts and their mutual transformation caused changes in the depolymerization degree, leading to a range of viscous activation energies, conductive activation energies, surface tension, and melt densities. Additionally, the logarithm of viscosity varied linearly with the logarithm of electrical conductivity (slope: 0.67–1.54). Meanwhile, the surface tension and melt density decreased with temperature. Consideration of these interrelations is indispensable during the development of chromium-containing slag glass ceramics, particularly for pilot and industrial applications.
Impact of the Current US Preventive Services Task Force Recommendations for Cervical Cancer Screening in Young Women 21 to 29 Years Old
Authors: Morris C Paul , Chowsilpa Sayanan , Mustafa Sara , Chan Isaac , Miller Daniel , Maleki Zahra , Rodriguez Erika F 
Published: January 2020

Abstract

Objectives
In 2012, the US Preventive Services Task Force decreased the recommended frequency of cervical cytology screening to once every 3 years and recommended against testing women younger than 21 years regardless of sexual history. We evaluated the impact of this in 21 to 29-year-old women at a tertiary care academic medical center in 2011 and 2017.

Methods
We retrospectively analyzed Papanicolaou test results at two time points in 21- to 29-year-old women.

Results
There was a decrease in the number of high-grade lesions in 21- to 25-year-old women (odds ratio [OR], 0.36) from 2011 to 2017. Within the 26- to 29-year-old patient group, there was a trend toward a higher percentage of high-grade squamous intraepithelial lesion (HSIL) in 2017 compared to 2011 on cytology, which did not reach statistical significance (OR, 1.46). However, follow-up histologic specimens showed a higher percentage of HSIL in 2017 compared to 2011 in this age group (OR, 2.16).

Conclusions
Our findings suggest that the cervical cancer screening guidelines introduced in 2012 have not had a detrimental impact on the outcomes of cervical cancer screening for 21- to 25-year-old women. However, we need to continue monitoring the effects of decreased screening in 26- to 29-year-old women.