bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the kinematic algebra for BCJ numerators beyond the MHV sector
Authors: Chen Gang , Johansson Henrik , Teng Fei , Wang Tianheng 
Published: November 2019

AbstractThe duality between color and kinematics present in scattering amplitudes of Yang-Mills theory strongly suggests the existence of a hidden kinematic Lie algebra that controls the gauge theory. While associated BCJ numerators are known on closed forms to any multiplicity at tree level, the kinematic algebra has only been partially explored for the simplest of four-dimensional amplitudes: up to the MHV sector. In this paper we introduce a framework that allows us to characterize the algebra beyond the MHV sector. This allows us to both constrain some of the ambiguities of the kinematic algebra, and better control the generalized gauge freedom that is associated with the BCJ numerators. Specifically, in this paper, we work in dimension-agnostic notation and determine the kinematic algebra valid up to certain 𝒪 ((εi · εj)2) terms that in four dimensions compute the next-to-MHV sector involving two scalars. The kinematic algebra in this sector is simple, given that we introduce tensor currents that generalize standard Yang-Mills vector currents. These tensor currents control the generalized gauge freedom, allowing us to generate multiple different versions of BCJ numerators from the same kinematic algebra. The framework should generalize to other sectors in Yang-Mills theory.
Quantum impurity models from conformal field theory
Authors: Wu Ying-Hai , Tu Hong-Hao 
Published: November 2019

Abstract
The coupling between localized magnetic moments and itinerant electrons presents a plethora of interesting physics. The low-energy physics of some quantum impurity systems can be described using conformal field theory (CFT). In this paper, the connection between quantum impurity models and CFT is further strengthened as we construct a class of exactly solvable models with ground states given by CFT correlators. The method developed here is completely analytical and can be applied to fermions with an arbitrary number of colors and multiple impurities. Numerical calculations are performed to characterize certain aspects of our models for which we do not have analytical results.
Wall-crossing and operator ordering for ’t Hooft operators in $$ \mathcal{N} $$ = 2 gauge theories
Authors: Hayashi Hirotaka , Okuda Takuya , Yoshida Yutaka 
Published: November 2019

Abstract
We study half-BPS ’t Hooft line operators in 4d $$ \mathcal{N} $$
N
= 2 U(N ) gauge theories on S1× ℝ3 with an Ω-deformation. The recently proposed brane construction of ’t Hooft operators shows that non-perturbative contributions to their correlator are identified with the Witten indices of quiver supersymmetric quantum mechanics. For the products of minimal ’t Hooft operators, a chamber in the space of Fayet-Iliopoulos parameters in the quantum mechanics corresponds to an ordering of the operators inserted along a line. These considerations lead us to conjecture that the Witten indices can be read off from the Moyal products of the expectation values of the minimal ’t Hooft operators, and also that wall- crossing occurs in the quantum mechanics only when the ordering of the operators changes. We confirm the conjectures by explicitly computing the Witten indices for the products of two and three minimal ’t Hooft operators in all possible chambers.
On finite-size d-branes in superstring theory
Authors: Mattiello Luca , Sachs Ivo 
Published: November 2019

Abstract
We test exact marginality of the deformation describing the blow-up of a zero- size D(−1) brane bound to a background of D3-branes by analyzing the equations of motion of superstring field theory to third order in the size. In the process we review the derivation of the instanton profile from string theory, extending it to include α′-corrections.
Differential autogrooming response to the tracheal mite Acarapis woodi by the honey bees Apis cerana and Apis mellifera
Authors: Sakamoto Y. , Maeda T. , Yoshiyama M. , Konno F. , Pettis J. S. 
Published: November 2019

AbstractThe infestation of honey bees by the endoparasitic tracheal miteAcarapis woodiwas first discovered inApis melliferaon the Isle of Wight, England, and the mite has since spread to all continents except Australia. Since 2010, this tracheal mite has spread rapidly in the Japanese honey bee,Apis cerana japonica, of mainland Japan, causing considerable colony mortality. In contrast, infestations by the mites in the imported and managed European honey bee,A. mellifera, have rarely been observed in Japan. A previous laboratory experiment revealed a difference in susceptibility by demonstrating that the tracheal mite more frequently enters tracheae ofA. ceranathan those ofA. mellifera. In this study, we compared autogrooming responses ofA. ceranaandA. melliferaby depositing a mite on each honey bee’s mesoscutum, and we then assessed the efficacy of autogrooming to remove the mite. The bees that received mites more frequently showed an autogrooming response compared to unchallenged bees in both bee species. However, a significantly greater proportion ofA. melliferaindividuals autogroomed compared toA. cerana. In addition, when bees autogroomed,A. melliferaremoved the tracheal mite more effectively thanA. cerana. When considering all bees in the mite-deposited group, the proportion of mite removal inA. melliferawas almost twice as high as that inA. cerana. Thus, the difference in susceptibility to the tracheal mite between these two bee species is attributed to the difference in the behavioral response threshold to mites and the effectiveness of mite removal by grooming.
Development of immunochromatographic device as a point-of-care tool for serodiagnosis of human strongyloidiasis cases
Authors: Sadaow Lakkhana , Sanpool Oranuch , Rodpai Rutchanee , Boonroumkaew Patcharaporn , Maleewong Wanchai , Intapan Pewpan M. 
Published: November 2019

AbstractHuman strongyloidiasis is an important gastrointestinal disease with an estimated 30 to 100 million people infected. Prevalence is generally underestimated since many infections are asymptomatic, and traditional diagnostic tests based on parasitological examination of stool samples are not adequately sensitive. Serological tests are useful and supportive but are still only available in a reference research setting. We made an immunochromatographic test (ICT) kit for rapid serodiagnosis of human strongyloidiasis. The antigen used in the ICT kit was extracted from larvae of Strongyloides stercoralis. Diagnostic efficacy of the kit was evaluated using human serum samples from strongyloidiasis patients, healthy persons, and those with other parasitoses. When using a cutoff level of 0.5 or above, the diagnostic sensitivity, specificity, and positive and negative predictive values at the prevalence of infection of 34.4%, were 93.3%, 83.7%, 76.7%, and 95.6%, respectively. This ICT kit is easy to use at the point-of-care and a result can be obtained in 15 min. Sophisticated instruments and highly trained staff are not required. It can be used in several diagnostic and public-health settings, e.g., prevalence surveys in endemic areas, confirmation and monitoring of cure post-treatment, diagnosis and screening of infected but asymptomatic individuals, and populations “at risk” for hyperinfection syndrome or disseminated strongyloidiasis if they are given immunosuppressive treatment for other conditions.
Right place. Right time. Right tool: guidance for using target analysis to increase the likelihood of invasive species detection
Authors: Morisette Jeffrey T. , Reaser Jamie K. , Cook Gericke L. , Irvine Kathryn M. , Roy Helen E. 
Published: November 2019

AbstractIn response to the National Invasive Species Council’s 2016–2018 Management Plan, this paper provides guidance on applying target analysis as part of a comprehensive framework for the early detection of and rapid response to invasive species (EDRR). Target analysis is a strategic approach for detecting one or more invasive species at a specific locality and time, using a particular method and/or technology(ies). Target analyses, which are employed across a wide range of disciplines, are intended to increase the likelihood of detection of a known target in order to maximize survey effectiveness and cost-efficiency. Although target analyses are not yet a standard approach to invasive species management, some federal agencies are employing target analyses in principle and/or in part to improve EDRR capacities. These initiatives can provide a foundation for a more standardized and comprehensive approach to target analyses. Guidance is provided for improving computational information. Federal agencies and their partners would benefit from a concerted effort to collect the information necessary to perform rigorous target analyses and make it available through open access platforms.
Development and evaluation of two TaqMan assays for generic detection of Dickeya species
Authors: Zijlstra Carolien , De Haas Lia Groenenboom – , Krijger Marjon , Verstappen Els , Warris Sven , de Haan Eisse , van der Wolf Jan 
Published: November 2019

AbstractTwo TaqMan assays were developed for generic detection of Dickeya species in plant material. The assays enabled detection of all strains of D. chrysanthemi, D. dadantii, D. dianthicola, D. solani and D. zeae tested, but only weak reactions were found with strains of D. paradisiaca. The assays enabled detection of as low as 100 fg of target DNA in a background of potato DNA. The assays were evaluated with DNA extracted from potato tuber extracts, in which different Dickeya species can be present. Results of both assays were highly similar indicating that they can be used reliably in potato seed testing programs.
Towards Increased Understanding of Open Data Use for Software Development
Authors: Grzenda Maciej , Legierski Jaroslaw 
Published: November 2019

AbstractThe way open data resources of varied type and volume are used by software applications remains only partly known. In this study, following CRoss-Industry Standard Process for Data Mining, we propose a methodology for collecting and analyzing access data describing the use of open data resources by individual software applications. The methodology includes novel categorization of the data collected at an exposition portal providing access to underlying open data portals and third-party services. Furthermore, it enables research into the use of both different open data resources and resource groups such as Big Data resources for software development. We apply the methodology to analyze the re-use of open urban data during reference software development events. The identification of open data use by individual applications is largely improved compared to baseline scenario, as shown by numerical indicators including F1 measure. Insight into re-use of data streams and actual development time is obtained.
The interplay between psychological need satisfaction and psychological need frustration within a work context: A variable and person-oriented approach
Authors: Rouse Peter C. , Turner Philip J. F. , Siddall Andrew G. , Schmid Julia , Standage Martyn , Bilzon James L. J. 
Published: November 2019

AbstractA plethora of empirical data support a positive (or “brighter”) pathway to optimal human functioning as specified within Basic Psychological Needs Theory (Ryan and Deci in Psychol Inq 11(4):319–33, 2000). Yet, far less is known about the negative (or “darker”) pathway, a process evoking of human dysfunction and ill-being (cf. Vansteenkiste and Ryan in J Psychother Integr 23(3):263, 2013). Further, debate surrounds the independence and interplay between psychological need satisfaction and psychological need frustration and how these dynamic constructs are experienced within individuals. In this work, variable and person-oriented analyses were employed to: (i) investigate the relationships between the basic psychological needs and symptoms of stress, depression and anxiety as well as with life satisfaction; and (ii) identify different psychological need profiles and their relationship with psychological function. Participants (N = 2236;MAge = 42.16 years;SD = 7.8) were UK-based operational firefighters who completed an online survey. Results of regression analyses showed a moderating effect of psychological need satisfaction on the relationship between need frustration and negative psychological symptoms. Latent profile analyses revealed five distinct basic psychological need profiles that carry implications for human psychological functioning. Some support for an asymmetrical relationship between need satisfaction and need frustration emerged (Vansteenkiste and Ryan in J Psychother Integr 23(3):263, 2013), yet, examples of above average need satisfaction and frustration scores were also observed. Worker profiles where psychological need frustration prevailed over need satisfaction had the poorest psychological health.
Predicting early career productivity of PhD economists: Does advisor-match matter?
Authors: García-Suaza Andrés , Otero Jesús , Winkelmann Rainer 
Published: November 2019

AbstractWe assess the role played by department rank and advisor-match on the early stage productivity of recent PhDs in economics using a tailor-made data set based on RePEc. After allowing for the potential influence of other factors, including gender and field of specialisation, we find as expected that both advisory quality and rank of the graduation institution are positively related to the academic productivity of graduates. However, in top institutions, students working with the most productive academics do not outperform others unless they co-author with their advisor. For students in non-top institutions, being advised by the best academics is always associated with a higher research output. Possible explanations for this difference are pointed out, including selection and differences in advising styles.
The Impact of Mineral Dissolution on Drainage Relative Permeability and Residual Trapping in Two Carbonate Rocks
Authors: Niu Ben , Krevor Samuel 
Published: November 2019

AbstractCarbon dioxide injection into deep saline aquifers is governed by a number of physico-chemical processes including mineral dissolution and precipitation, multiphase fluid flow, and capillary trapping. These processes can be coupled; however, the impact of fluid–rock reaction on the multiphase flow properties is difficult to study and is not simply correlated with variations in porosity. We observed the impact of rock mineral dissolution on multiphase flow properties in two carbonate rocks with distinct pore structures. Observations of steady-state $$\hbox {N}_2$$N2–water relative permeability and residual trapping were obtained, along with mercury injection capillary pressure characteristics. These tests alternated with eight stages in which 0.5% of the mineral volume was uniformly dissolved into solution from the rock cores using an aqueous solution with a temperature-controlled acid. Variations in the multiphase flow properties did not relate simply to changes in porosity, but corresponded to the changes in the underlying pore structure. In the Ketton carbonate, dissolution resulted in an increase in the fraction of pore volume made up by the smallest pores and a decrease in the fraction made up by the largest pores. This resulted in an increase in the relative permeability to the nonwetting phase, a decrease in the relative permeability to the wetting phase, and a modest, but systematic decrease in residual trapping. In the Estaillades carbonate, dissolution resulted in an increase in the fraction of pore volume made up by pores in the central range of the initial pore size distribution, and a corresponding decrease in the fraction made up by both the smallest and largest pores. This resulted in a decrease in the relative permeability to both the wetting and nonwetting fluid phases and no discernible impact on the residual trapping. In summary, the impact of rock matrix dissolution will be strongly dependent on the impact of that dissolution on the underlying pore structure of the rock. However, if the variation in pore structure can be observed or estimated with modelling, then it should be possible to estimate the impacts on multiphase flow properties.
Targeted Mutational Profiling and a Powerful Risk Score as Additional Tools for the Diagnosis of Papillary Thyroid Cancer
Authors: Kocsis-Deák Barbara , Árvai Kristóf , Balla Bernadett , Tóbiás Bálint , Kohánka Andrea , Járay Balázs , Horányi János , Podani János , Takács István , Putz Zsuzsanna , Kósa János , Lakatos Péter 
Published: November 2019

AbstractNowadays, the complementary diagnostics based on the suspicious thyroid lesion specific mutational state analysis is indispensable in the clinical practice. We aimed to test and validate our novel 568-mutational hotspot panel (23 cancer-related genes) on papillary thyroid cancers (PTCs) and their tumor-free pairs to find the most powerful mutation pattern related to PTC. The sequencing method was carried on with Ion Torrent PGM on 67 thyroid tissue samples. The most commonly detected mutation was the BRAF c.1799 T > A in all non-classical PTC cases. We utilized a multivariate statistical method (CVA) to determine a discrimination score based on mutational data array and to assess malignancy risk. Based on variants, the BRAF gene has by far the highest indicative power, followed by TSHR and APC. We highlighted novel aspects of the mutational profile and genetic markers of PTC. CVA has correctly assigned most of the samples based on the mutation frequencies and different variables of the selected genes, with high analytical probabilities. The final goal is to set up a new comprehensive rule-in and rule-out test to support the clinical decision making mainly in inconclusive fine-needle aspiration biopsy cases.
The Japanese Breast Cancer Society Clinical Practice Guidelines, 2018 edition: the tool for shared decision making between doctor and patient
Authors: Iwata Hiroji , Saji Shigehira , Ikeda Masahiko , Inokuchi Masashi , Uematsu Takayoshi , Toyama Tatsuya , Horii Rie , Yamauchi Chikako 
Published: November 2019

AbstractThe Breast Cancer Clinical Practice Guidelines, 2018 edition, written in Japanese and organized by the Japanese Breast Cancer Society, were published in Japanese in May 2018. The process of making these guidelines, as well as the content, was largely changed and compared with previous editions. The concept of these guidelines is to act as a support tool for shared decision making between doctor and patient. The procedure of creating the guidelines referred to Minds Handbook for Clinical Practice Guideline Development 2014. This guideline, written in Japanese, consists of two booklets: (1) the epidemiology and diagnosis booklet covering screening, radiological, and pathological diagnosis and (2) the treatment booklet covering surgical therapy, radiation therapy, and systemic therapy. This review article consists of five parts, including the history of the Breast Cancer Clinical Practice Guidelines, the concept, process, content, and recommendation grade. I believe this brief summary concerning the Breast Cancer Clinical Practice Guidelines 2018 edition in English will be helpful for both Japanese and foreign investigators.
The Cross Talk between Cancer Stem Cells/Cancer Initiating Cells and Tumor Microenvironment: The Missing Piece of the Puzzle for the Efficient Targeting of these Cells with Immunotherapy
Authors: Ravindran Shilpa , Rasool Saad , Maccalli Cristina 
Published: November 2019

AbstractCancer Stem Cells/Cancer Initiating Cells (CSCs/CICs) is a rare sub-population within a tumor that is responsible for tumor formation, progression and resistance to therapies. The interaction between CSCs/CICs and tumor microenvironment (TME) can sustain “stemness” properties and promote their survival and plasticity. This cross-talk is also pivotal in regulating and modulating CSC/CIC properties. This review will provide an overview of the mechanisms underlying the mutual interaction between CSCs/CICs and TME. Particular focus will be dedicated to the immunological profile of CSCs/CICs and its role in orchestrating cancer immunosurveillance. Moreover, the available immunotherapy strategies that can target CSCs/CICs and of their possible implementation will be discussed. Overall, the dissection of the mechanisms regulating the CSC/CIC-TME interaction is warranted to understand the plasticity and immunoregulatory properties of stem-like tumor cells and to achieve complete eradications of tumors through the optimization of immunotherapy.
Effect of anodized zirconium implants on early osseointegration process in adult rats: a histological and histomorphometric study
Authors: Tano de la Hoz María Florencia , Katunar María Rosa , González Ariel , Gomez Sanchez Andrea , Díaz Alcira Ofelia , Ceré Silvia 
Published: November 2019

AbstractSince surface plays a key role in bioactivity, the response of the host to the biomaterial will determine the success or failure of the prosthesis. The purpose of this study is to make an exhaustive analysis of the histological and histochemical characteristics of new bone tissue around Zr implants anodized at 60 V (Zr60) supported by histomorphometric methods in a rat model. Fibrous tissue was observed around the control implants (Zr0) and osteoblasts were identified on the trabeculae close to the implantation site that showed typical cytological characteristics of active secretory cells, regardless of the surface condition. The histomorphometrical analysis revealed a significant increase in cancellous bone volume, trabecular thickness and in trabecular number together with a decrease in trabecular separation facing Zr60. TRAP staining showed that there was a relative increase in the number of osteoclasts for Zr60. In addition, a larger number of osteoclast with a greater number of nuclei were detected in the tibiae for Zr60. This research demonstrated that the new bone microarchitecture in contact with Zr60 is able to improve the early stages of the osseointegration process and consequently the primary stability of implants which is a crucial factor to reduce recovery time for patients.
Vaccination with (1–11)E2 in alum efficiently induces an antibody response to β-amyloid without affecting brain β-amyloid load and microglia activation in 3xTg mice
Authors: Mantile Francesca , Capasso Angelo , Villacampa Nadia , Donnini Maria , Liguori Giovanna L. , Constantin Gabriela , De Berardinis Piergiuseppe , Heneka Michael T. , Prisco Antonella 
Published: November 2019

AbstractImmunization against β-amyloid (Aβ) is pursued as a possible strategy for the prevention of Alzheimer’s disease (AD). In clinical trials, Aβ 1–42 proved poorly immunogenic and caused severe adverse effects; therefore, safer and more immunogenic candidate vaccines are needed. Multimeric protein (1–11)E2 is able to induce an antibody response to Aβ, immunological memory, and IL-4 production, with no concomitant anti-Aβ T cell response. Antisera recognize Aβ oligomers, protofibrils, and fibrils. In this study, we evaluated the effect of prophylactic immunization with three doses of (1–11)E2 in alum in the 3xTg mouse model of AD. Immunization with (1–11)E2 efficiently induced anti-Aβ antibodies, but afforded no protection against Aβ accumulation and neuroinflammation. The identification of the features of the anti-Aβ immune response that correlate with the ability to prevent Aβ accumulation remains an open problem that deserves further investigation.