bluuebunny/crossref_metadata_2025_split huggingface dataset:
“So What?”: A Conversation with John W. O’Malley
Authors: Colombo Emanuele 
Published: January 2020

John W. O’Malley, a member of the Society of Jesus, is currently a university professor in the Theology Department of Georgetown University, Washington, DC. He holds a PhD in history from Harvard University. His specialty is the religious culture of early modern Europe. O’Malley has written and edited a number of books, eight of which have won best-book awards. The First Jesuits (Cambridge, MA: Harvard University Press, 1993), perhaps his best-known work, received both the Jacques Barzun Prize for Cultural History from the American Philosophical Society and the Philip Schaff Prize from the American Society for Church History. It has been translated into twelve languages and its publication opened a new era in the study of the Society. Since then, the Jesuits have attracted greater attention from scholars of all disciplines on an international basis. O’Malley has continued to write about early Jesuits and the subsequent history of the Jesuits: his main essays on Jesuit history are now collected in the first volume of Brill’s Jesuit Studies series, Saints or Devils Incarnate?: Studies in Jesuit History (Leiden, 2013).
In the last few years, O’Malley published with Harvard University Press a trilogy on the three last councils in the history of the Catholic Church: What Happened at Vatican ii
(2008), Trent: What Happened at the Council (2012), and Vatican I: The Council and the Making of the Ultramontane Church (2018). A comparative view of the three councils is offered now in his most recent book, When Bishops Meet: An Essay Comparing Trent, Vatican I, and Vatican ii
(2019). O’Malley has lectured widely around the world to both professional and general audiences. He is past president of the Renaissance Society of America and the American Catholic Historical Association. He holds the Johannes Quasten Medal from The Catholic University of America for distinguished service in religious studies. In 1995, he was elected to the American Academy of Arts and Sciences; in 1997, to the American Philosophical Society; and in 2001, to the Accademia Ambrosiana, Milan. He holds lifetime achievement awards from the Society for Italian Historical Studies, the Renaissance Society of America, and the American Catholic Historical Association.
At the origin of the following interview there are three conversations Emanuele Colombo had with O’Malley in Chicago, in 2017 and 2018, as a follow-up of a lecture he gave on his life, “My Life of Learning,” now published in The Catholic Historical Review.
1
The Effect of the Madden–Julian Oscillation on the North Atlantic Oscillation Using Idealized Numerical Experiments
Authors: Fromang Sebastien , Rivière Gwendal 
Published: January 2020

AbstractThe aim of the paper is to investigate the influence of the Madden–Julian oscillation (MJO) on the North Atlantic Oscillation (NAO) using a quasigeostrophic model on the sphere. A simplified forcing based on potential vorticity anomalies in the tropics is used to mimic the MJO. The idealized nature of our setup allows us to determine the distinct roles played by stationary and synoptic waves. This is done by means of several series of almost 10 000 short runs of 30 days. Ensemble averages and a streamfunction budget analysis are used to study the modifications of the flow induced by the MJO. We find that a stationary Rossby wave is excited in the tropics during MJO phase 3. The western part of the Pacific jet is displaced poleward, which modifies the transient eddy activity in that basin. These changes create a ridge south of Alaska, which favors equatorward propagation of synoptic waves and larger poleward eddy momentum fluxes from the eastern Pacific toward the Atlantic, increasing the frequency of occurrence of the positive NAO events. The situation is essentially reversed following phase 6 of the MJO and conducive to the negative phase of the NAO. For a realistic MJO forcing amplitude, we find increases in both NAO phases to be around 30%, in reasonable agreement with the observations given the model simplicity. Finally, we present a series of experiments to assess the relative importance of linear versus nonlinear effects.
Dynamically Downscaled Climate Change Projections for the South Asian Monsoon: Mean and Extreme Precipitation Changes and Physics Parameterization Impacts
Authors: Huo Yiling , Peltier W. Richard 
Published: January 2020

AbstractThe extreme concentration of population over South Asia makes it critical to accurately understand the global warming impact on the South Asian monsoon (SAM), but the complex orography of the region makes future projections of monsoon intensity technically challenging. Here we describe a series of climate projections constructed using the Weather Research and Forecasting (WRF) Model for South Asia to dynamically downscale a global warming simulation constructed using the Community Earth System Model under the representative concentration pathway 8.5 (RCP8.5) scenario. A physics-based miniensemble is employed to investigate the sensitivity of the projected change of the SAM to the implementation of different parameterization schemes in WRF. We analyze not only the changes in mean seasonal precipitation but also the impact of the warming process on precipitation extremes. All projections are characterized by a consistent increase in average monsoon precipitation and a fattening of the tail of the daily rainfall distribution (more than a 50% decrease in the return periods of 50-yr extreme rainfall events by the end of the twenty-first century). Further analysis based on one of the WRF physics ensemble members shows that both the average rainfall intensity changes and the extreme precipitation increases are projected to be slightly larger than expectations based upon the Clausius–Clapeyron thermodynamic reference of 7% °C−1of surface warming in most parts of India. This further increase can be primarily explained by the fact that the surface warming is projected to be smaller than the warming in the midtroposphere, where a significant portion of rain originates, and dynamical effects play only a secondary role.
Correlation of Nasal Fluid Biomarkers and Symptoms in Patients with Persistent Allergic Rhinitis
Authors: Kim Su Il , Kwon Oh Eun , Park Jung Min , Doo Jeon Gang , Kim Seok Hyun , Jung Hae Rim , Min Jin Young , Kim Sung Wan , Lee Young Chan , Eun Young-Gyu 
Published: January 2020

Objectives: This study investigated whether the biomarkers present in nasal fluid reflect the severity of symptoms in patients with persistent allergic rhinitis (PAR). Methods: We enrolled 29 PAR patients complaining of nasal symptoms and testing positive to skin prick test. Patients’ total nasal symptom score (TNSS) was measured and their nasal lavage fluid (NALF) was collected. The levels of biomarkers including Clara cell protein 16 (CC16), tryptase, and interleukin 5 (IL-5) in NALF were determined via enzyme-linked immunosorbent assay (ELISA). Results: PAR patients were classified into persistent mild and persistent moderate-to-severe groups according to the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines. The CC16 alone was significantly negatively correlated with TNSS ( P < .05). Further, the CC16 level was significantly lower in persistent moderate-to-severe group than persistent mild group of patients ( P < .05). Conclusions: The levels of CC16 alone among several NALF biomarkers showed an inverse correlation with symptoms of PAR patients.
Are Trait Emotional Competencies and Heart Rate Variability Linked to Mental Health of Coronary Heart Disease Patients?
Authors: Elise Batselé , Eynde Sophie Vanden , Egée Nathalie , Lamotte Michel , Van de Borne Philippe , Carole Fantini-Hauwel 
Published: January 2020

Purpose Depression and anxiety have been extensively associated with adverse outcomes in coronary heart disease patients. However, psychological and physiological processes underlying the persistence of these troubles in coronary heart disease patients attending cardiac rehabilitation are poorly investigated. Trait emotional competencies and heart rate variability could be some of these processes. Thus, the aim of this study was to assess the predictive value of trait emotional competencies and heart rate variability on depression and anxiety symptoms persistence in coronary heart disease patients. Methods Eighty-four patients who recently presented a myocardial infarction were evaluated at the beginning of cardiac rehabilitation. Forty-two patients continued their rehabilitation program and were then assessed three months later. They completed the Profile of Emotional Competence as well as the Hospital Anxiety and Depression Scale and underwent a 5-minute resting heart rate variability measure. Results Low trait emotional competencies score predicted depression symptoms persistence, but unexpectedly, high trait emotional competencies score was also associated with withdrawal from cardiac rehabilitation. Contrary to our expectations, heart rate variability did not predict depression or anxiety symptoms persistence and was not associated with trait emotional competencies. Conclusions This study is the first to report an association between trait emotional competencies and depression symptoms persistence in coronary heart disease patients. However, heart rate variability was not associated with either depression or anxiety supporting the idea of mixed literature and highlighting the need of future research.
Rethinking Patellar Tendinopathy and Partial Patellar Tendon Tears: A Novel Classification System
Authors: Golman Mikhail , Wright Margaret L. , Wong Tony T. , Lynch T. Sean , Ahmad Christopher S. , Thomopoulos Stavros , Popkin Charles A. 
Published: January 2020

Background:Patellar tendinopathy is an overuse injury of the patellar tendon frequently affecting athletes involved in jumping sports. The tendinopathy may progress to partial patellar tendon tears (PPTTs). Current classifications of patellar tendinopathy are based on symptoms and do not provide satisfactory evidence-based treatment guidelines.Purpose:To define the relationship between PPTT characteristics and treatment guidelines, as well as to develop a magnetic resonance imaging (MRI)–based classification system for partial patellar tendon injuries.Study Design:Cohort study (prognosis); Level of evidence, 2.Methods:MRI characteristics and clinical treatment outcomes were retrospectively reviewed for 85 patients with patellar tendinopathy, as well as 86 physically active control participants who underwent MRI of the knee for other conditions. A total of 56 patients had a PPTT and underwent further evaluation for tear size and location. The relationship between tear characteristics and clinical outcome was defined with use of statistical comparisons and univariate and logistic regression models.Results:Of the 85 patients, 56 had partial-thickness patellar tendon tears. Of these tears, 91% involved the posterior and posteromedial regions of the proximal tendon. On axial MRI views, patients with a partial tear had a mean tendon thickness of 10 mm, as compared with 6.2 mm for those without ( P < .001). Eleven patients underwent surgery for their partial-thickness tear. All of these patients had a tear >50% of tendon thickness (median thickness of tear, 10.3 mm) on axial views. Logistic regression showed that tendon thickness >8.8 mm correlated with the presence of a partial tear, while tendon thickness >11.45 mm and tear thickness >55.7% predicted surgical management.Conclusion:Partial-thickness tears are located posterior or posteromedially in the proximal patellar tendon. The most sensitive predictor for detecting the presence of a partial tear was patellar tendon thickness, in which thickness >8.8 mm was strongly correlated with a tear of the tendon. Tracking thickness changes on axial MRI may predict the effectiveness of nonoperative therapy: athletes with patellar tendon thickness >11.5 mm and/or >50% tear thickness on axial MRI were less likely to improve with nonoperative treatment. A novel proposed classification system for partial tears, the Popkin-Golman classification, can be used to guide treatment decisions for these patients.
Où en sommes-nous? An Overview of Successes and Challenges after 30 Years of Early Intervention Services for Psychosis in Quebec: Où en sommes-nous? Un aperçu des réussites et des problèmes après 30 ans de services d’intervention précoce pour la psychose au Québec
Authors: Bertulies-Esposito Bastian , Nolin Marie , Iyer Srividya N. , Malla Ashok , Tibbo Phil , Otter Nicola , Ferrari Manuela , Abdel-Baki Amal 
Published: January 2020

Introduction: Over the last 30 years, early intervention services (EIS) for first-episode psychosis (FEP) were gradually implemented in the province of Quebec. Such implementation occurred without provincial standards/guidelines and policy commitment to EIS until 2017. Although the literature highlights essential elements for EIS, studies conducted elsewhere reveal that important EIS components are often missing. No thorough review of Quebec EIS practices has ever been conducted, a gap we sought to address. Methods: Adopting a cross-sectional descriptive study design, an online survey was distributed to 18 EIS that existed in Quebec in 2016 to collect data on clinical, administrative, training, and research variables. Survey responses were compared with existing EIS service delivery recommendations. Results: Half of Quebec’s population had access to EIS, with some regions having no programs. Most programs adhered to essential components of EIS. However, divergence from expert recommendations occurred with respect to variables such as open referral processes and patient–clinician ratio. Nonurban EIS encountered additional challenges related to their geography and lower population densities, which impacted their team size/composition and intensity of follow-up. Conclusions: Most Quebec EIS offer adequate services but lack resources and organizational support to adhere to some core components. Recently, the provincial government has created EIS guidelines, invested in the development of new programs and offered implementation support from the National Centre of Excellence in Mental Health. These changes, along with continued mentoring and networking of clinicians and researchers, can help all Quebec EIS to attain and maintain recommended quality standards.
Dislocation after total hip arthroplasty: does head size really matter?
Authors: Ertaş Erkan Sabri , Tokgözoğlu A Mazhar 
Published: January 2020

Introduction: Recent advances in polyethylene and ceramic technologies has allowed us to use larger sized heads without compromising the wear properties of a total hip arthroplasty (THA). 1 benefit of this change has been proposed to be a lower incidence of dislocation. Methods: We retrospectively evaluated the dislocation rate in 913 THAs performed using the same standardised surgical technique employed by a single team of surgeons at our institution between 1995 and 2015. Patients were assigned to 2 groups: small (⩽28 mm), large diameter heads (⩾36 mm and larger). The cup position was measured and plotted to determine its status according to the Lewinnek’s safe zone (15° ± 10° for anteversion, 40° ± 10° for inclination). Results: 16 of the 472 small heads dislocated (3.4%) while 5 of the 441 in large head group (1.1%) ( p = 0.04). In all of the large head patients that dislocated the cup position was in the safe range of Lewinnek. However, in the large head group only 64.5% of the cups were in the safe zone. Conclusions: By changing the head size to 36 mm, we were able to decrease the dislocation rate significantly. Errors of cup positioning according to Lewinnek became oblivious when using large heads. In our opinion, using large heads in THA makes a difference in terms of dislocation.
What Outcome Measures Are Reported in the Management of Acromioclavicular Joint Injuries?
Authors: Reintgen Christian , Gerlach Erik B. , Schoch Bradley S. , Mamelson Kelly , Wright Thomas W. , Farmer Kevin W. , King Joseph J. 
Published: January 2020

Background: Lack of uniformity in reported outcomes makes comparisons between acromioclavicular joint (ACJ) injury studies challenging. Knowledge of common outcome measures and standardization will help orthopaedic surgeons report and compare outcomes more consistently. Purpose: To identify the most commonly reported outcome measures for ACJ injuries. Study Design: Systematic review. Methods: A systematic review was performed to identify all English-language original articles assessing any type of management of ACJ injuries (acute and chronic) in PubMed and Scopus from 2007 to 2017. Review articles, meta-analyses, studies with less than 5 patients, pediatric studies, technique articles, and biomechanical studies were excluded. The 100 top orthopaedic journals in the English literature were selected for review. Included studies were assessed for patient characteristics and the use of outcome variables, including range of motion (ROM), strength, patient-reported outcomes (PROs), satisfaction, return to work, return to sport, and complications. Results: A total of 605 unique articles were identified; 92 met the inclusion criteria. The average number of ACJ injuries per study was 37, with a mean weighted patient age of 36 years (range, 20.1-57.3 years). The mean follow-up was 36 months (range, 5-290 months). Acute injuries were reported in 59% of studies. ROM and strength measurements were reported in 22.8% and 5.4% of studies. Sixteen different PRO instruments were used. The most commonly reported measures were Constant score (75%), visual analog scale for pain (VAS-pain; 33%) score, American Shoulder and Elbow Surgeons (ASES) score (21%), Simple Shoulder Test (SST) score (19%), and University of California Los Angeles (UCLA; 17%) shoulder score. An average of 2.5 outcome measures per study were reported. The use of 4 or more outcome scores was associated with publication in higher–impact factor journals. Conclusion: Inconsistent reporting of multiple outcome measures is present in the ACJ injury literature. The best scoring system for assessing ACJ injury and treatment has not yet been agreed upon. Until improved scoring systems come into general use, we recommend that future literature on ACJ injuries use at least 4 outcome scores and include the commonly used outcome measures (Constant, VAS-pain, ASES, and SST scores) to enable future comparison of patient outcomes across publications.
Modifying a naturalistic language intervention for use in an elementary school classroom
Authors: Lane Justin D , Shepley Collin , Sartini Emily , Hogue Amanda 
Published: January 2020

Background and aims We evaluated a naturalistic language intervention (NLI) targeting expanded forms of expressive communication (e.g., two-word phrases) for elementary-aged children with autism spectrum disorder (ASD) and/or intellectual disability (ID). This study extends the findings of a previous study that evaluated an NLI for preschool-aged children who displayed social communication delays. In the previous study, one child was considered a non-responder to the original intervention; children with similar pre-intervention profiles to the non-responder were recruited for this study to evaluate a modified version of the NLI with a new participant group. Methods The NLI was evaluated within the context of a multiple probe design across children, with sessions conducted in a public school classroom. The modifications to the NLI resulted in varying dosages of the intervention provided across sessions and children. To analyze the moderating influence of the variation in dosage, we graphed each dosage variable to allow for a formative analysis of changes within and across study conditions. Results Results indicated increases in the target behavior for all three children when compared to probe sessions; however, for one child the consistency of changes were variable and, as such, may not be socially significant. Conclusions and implications This study extends the literature on conducting NLIs with minimally verbal children with ASD and ID in dynamic settings, like classrooms. Educators and related professionals can capitalize on natural opportunities for social communication in children who are minimally verbal but imitative by using naturalistic procedures to promote verbalizations during age-appropriate activities.
Assessment of the value of the different variants of abnormal digital rectal examination finding in predicting carcinoma of the prostate: a preliminary report of a two-center study
Authors: Irekpita Eshiobo , Achor George Okwudili , Alili Ugochukwu 
Published: January 2020

AbstractBackgroundDigital rectal examination is a veritable tool for the clinical diagnosis and screening for carcinoma of the prostate. This study aims to assess the value of the different variables which constitute abnormal digital rectal examination (DRE) findings.ResultsFollowing ethical approval, one hundred and thirty-one men met the inclusion criteria and were enrolled in the study. The peak incidence of abnormal DRE finding was in the 8th decade of life, while the PPV was 66.5%. Of the total, 44 (33.5%) were nodular hyperplasia, 12 (9.2%) were prostate intra-epithelia neoplasia, while 75 (57.3%) were adenocarcinoma. With a positive predictive value (PPV) of 73.3%, a hard nodular feel was the only abnormal DRE finding that independently and significantly predicted the risk of prostatic adenocarcinoma. A suspicious nodule and obliterated median groove had PPV of 23.1% and lobar asymmetry, 0%. There was a statistically significant correlation (P = 0.005) between DRE findings and histology, between PSA and histology (P = 0.000) and between the size of the prostate and PSA value (P = 0.021). The mean size of the prostate was 101.2 g, standard deviation 92.11783, maximum 648 g and minimum 13.6 g.ConclusionMost of the variants of abnormal DRE findings do not sufficiently predict the risk of adenocarcinoma on their own. They need to be in combination with other DRE findings or a raised PSA to significantly predict adenocarcinoma.
Microscopy cell nuclei segmentation with enhanced U-Net
Authors: Long Feixiao 
Published: January 2020

Abstract
Background
Cell nuclei segmentation is a fundamental task in microscopy image analysis, based on which multiple biological related analysis can be performed. Although deep learning (DL) based techniques have achieved state-of-the-art performances in image segmentation tasks, these methods are usually complex and require support of powerful computing resources. In addition, it is impractical to allocate advanced computing resources to each dark- or bright-field microscopy, which is widely employed in vast clinical institutions, considering the cost of medical exams. Thus, it is essential to develop accurate DL based segmentation algorithms working with resources-constraint computing.

Results
An enhanced, light-weighted U-Net (called U-Net+) with modified encoded branch is proposed to potentially work with low-resources computing. Through strictly controlled experiments, the average IOU and precision of U-Net+ predictions are confirmed to outperform other prevalent competing methods with 1.0% to 3.0% gain on the first stage test set of 2018 Kaggle Data Science Bowl cell nuclei segmentation contest with shorter inference time.

Conclusions
Our results preliminarily demonstrate the potential of proposed U-Net+ in correctly spotting microscopy cell nuclei with resources-constraint computing.