bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Regulatory T-Cells (Tregs) in Benign Prostatic Pathologies: A Pilot Study
Authors: ATEŞ Erhan , AMASYALI Akın , ORYAŞIN Erman , YAVAŞOĞLU İrfan , YILMAZ Mustafa , BOZDOĞAN Bülent , EROL Haluk 
Published: November 2020

Objective: We aimed to evaluate the number and function of regulatory T (Treg) cells in peripheral blood and prostate tissues of patients with histopathologically diagnosed benign prostate hyperplasia (BPH) and asymptomatic chronic prostatitis.
Material and Methods: Blood and histopathological data of 19 patients (BPH=10, ACP=9) that underwent transurethral prostate resection were evaluated. Treg cell count in peripheral blood and prostatic tissue with flowcytometry, Forkhead box P3 (FOXP3) expression in prostatic tissue by reverse transcription polymerase chain reaction (PCR), and IL-17 measurement in blood samples with ELISA were performed.
Results: Flowcytometric analyses showed that mean CD4+T cell count and mean FOXP3 levels in both peripheral blood (CD4+T, p= 0.752; FOXP3, p= 1.000) and prostate tissue (CD4+T, p= 0.458; FOXP3, p= 0.590) were higher in the BPH group compared to the chronic prostatitis group. However this difference was not statistically significant. Similarly, the mean blood IL-17 levels were also higher in BPH groups, but the difference was not statistically significant (p= 0.870). The PCR analyses showed that mean FOXP3 gene expression in the tissue was higher in the chronic prostate group, but again there was no statistically significant difference between the groups (p= 0.116).
Conclusion: Since no statistically significant difference was found between BPH and chronic prostatitis in terms of Treg cell number and function in peripheral blood and prostatic tissue, our study supports the thesis that both these pathologies could be autoimmune inflammatory diseases.
Nueva técnica quirúrgica para el tratamiento de la retroniquia: avulsión parcial proximal
Authors: Córdoba-Fernández Antonio , Lobo-Martín Adrián 
Published: November 2020

La retroniquia u onicocriptosis proximal es una patología que se presenta con relativa frecuencia en las consultas de podología. La avulsión ungueal completa ha sido el tratamiento de elección descrito en la literatura para el abordaje de la patología. A pesar de ser efectiva, no está exenta de inconvenientes asociados a la pérdida de la función mecánica que la lámina ungueal tiene encomendada en el primer dedo de los pies. Para evitar o aminorar la aparición de estos inconvenientes, proponemos una alternativa sencilla consistente en la avulsión parcial proximal no incisional de la lámina ungueal dejando intacta la porción distal adherida al lecho hasta que la nueva lámina ungueal termine por desplazarla.
Fibroid arising in a mullerian duct remnant presenting as a pelvic mass-sonographic diagnosis with magnetic resonance imaging correlation
Authors: Singh Amandeep , Singh Gauravdeep 
Published: November 2020

Mullerian agenesis is a rare congenital anomaly characterized as aplasia or hypoplasia of uterus in women with normal development of secondary sex characteristics. Presence of leiomyoma in mullerian agenesis is very rare and only few cases have been reported in the literature. Ultrasound and MRI showed a large soft tissue mass in right adnexal region. A provisional diagnosis of mullerian agenesis associated with two pelvic masses was made. Histopathology confirmed the diagnosis of leiomyoma.
The Activities of the Polish Catholic Caritas in Great Britain, Italy and Denmark 1956–1962
Authors: Nir Roman 
Published: November 2020

Działalność polskiego Caritas katolickiego w Wielkiej Brytanii, Włoszech i Danii w latach 1956–1962
W 1945 r. ks. Rafał Gogoliński-Elston nawiązał kontakt z arcybiskupem krakowskim księciem Adamem Stefanem Sapiehą i krajową konferencją NCWC w celu niesienia pomocy przez NCWC Polakom w kraju za pośrednictwem Caritas w Polsce. W latach 1946–1948 z magazynów NCWC w Wielkiej Brytanii wysłano do Polski lekarstwa, odzież, żywność o wartości 80 000 dolarów. Do Polski wysłano sześć ciężarówek z darami dla Caritasu, domy dziecka otrzymały koce, pościel, sprzęt kuchenny, artykuły piśmiennicze i biurowe, takie jak papier, ołówki, tusz i maszyny do pisania.W latach 1950–1951 dostarczono do Polski 80 pudeł z lekarstwami i sprzętem medycznym o wartości ponad 10 000 dolarów. W 1952 r. ks. R. Gogoliński-Elston założył w Wielkiej Brytanii polski oddział Caritas. W latach 1952–1957 oddział ten wysłał do Polski 4000 paczek żywnościowych CARE za sumę 40 000 dolarów, 6000 paczek żywnościowych z Departamentu Rolnictwa USA na kwotę 30 000 dolarów. W latach 1950–1960 polska Caritas wsparła paczkami świątecznymi polskich księży, którzy znaleźli się w trudnych warunkach finansowych. Każdego roku w okresie Bożego Narodzenia wysyłano ponad 100 paczek o łącznej wartości ponad 4000 dolarów. Caritas pomagała dzieciom i młodzieży w polskich szkołach katolickich w Wielkiej Brytanii, udzielając także stypendiów uczniom. Sfinansowała 106 obozów letnich dla 2650 dzieci. W listopadzie 1956 r. ks. Gogoliński-Elston założył oddziały polskiej Caritas w Danii i Szwecji. Dania otrzymała środki finansowe na dwie szkoły dla dzieci polskich, 3 ośrodki polonijne, 6 mobilnych bibliotek polskich, na teatr młodzieżowy, a także na działalność polskiego księdza (łącznie 4780 dolarów). Szwecja otrzymała pieniądze na dofinansowanie jedenastu polskich szkół sobotnich, sześciu obwoźnych bibliotek z polskimi książkami, jednego klubu młodzieżowego (łącznie 3890 dolarów).
Wizerunek Jana Pawła II w prasie polonijnej USA na przykładzie ,,Dziennika Związkowego’’ i ,,Nowego Dziennika–Polish Weekly”
Authors: Janowiec Natalia 
Published: November 2020

Jan Paweł II był pierwszym w historii papieżem, który doceniał rolę, jaką odgrywają we współczesnym świecie środki masowego przekazu. Traktował media jako nowoczesną formę komunikacji, dzięki której Kościół katolicki mógłby wpływać na kształt życia społecznego i religijnego na świecie.
Niniejszy artykuł jest wstępną analizą wizerunku postaci Jana Pawła II w dwóch polonijnych tytułach prasowych ze Stanów Zjednoczonych: ,,Dzienniku Związkowym” i ,,Nowym Dzienniku–Polish Weekly”. Ze względu na ograniczone ramy tej publikacji przedstawiono jedynie krótką charakterystykę zagadnień, które zakwalifikowano jako istotne dla szerszego rozpoznania i zbadania tematu.
Parafia NSPJ w New Britain i jej duszpasterze na łamach „Dziennika Chicagoskiego” w latach 1894-1920
Authors: Szymański Józef 
Published: November 2020

Parafia nowobretańska miała charakter narodowy i personalny, liczyła około 7,5 tys. wiernych, i tak zaprezentowana została na łamach „Dziennika Chicagoskiego”. Jej pierwszy proboszcz, ks. Lucjan Bójnowski, pozostał na tym stanowisku 62 lata (1895-1957). W tym czasie zbudowano kościół drewniany, po 1902 r. murowany, a także szkołę i ochronkę, wydawano gazetę. Wokół tej parafii swoją działalność prowadziły różne towarzystwa religijne, kulturalne i narodowe mające na celu pogłębianie i podtrzymanie polskiej świadomości narodowej wśród emigrantów, więzi ze starym krajem, pogłębianie życia religijnego. Obok pomocy duchowej, uroczystych nabożeństw, parafia polska w New Britain dostarczyła do „błękitnej armii” wielu rekrutów, a także tysiące dolarów pomocy materialnej staremu krajowi. Do armii polskiej we Francji wstąpiło z tej parafii polskiej 290 ochotników. Łącznie do armii polskiej i amerykańskiej wstąpiło 965 Polaków. Z nich 123 oddało życie.
Ogromną rolę odegrała parafia polska przede wszystkim w sprawach odrodzenia poczucia narodowego i odrodzenia niepodległego Państwa Polskiego. Więź emigrantów polskich z Kościołem poza ojczystym krajem kształtowała poczucie tożsamości religijnej i narodowej.
Listy pasterskie, okólniki i inne pisma rektora Polskiej Misji Katolickiej, ks. Leona Łagody, w zbiorach Archiwum PMK w Paryżu
Authors: Zych Sławomir 
Published: November 2020

Celem artykułu jest przedstawienie działalności Polskiej Misji Katolickiej we Francji na przykładzie pism jej rektora ks. Leona Łagody. Autor dokonuje analizy zawartości tego zbioru, odnoszącego się głównie do lat 1929-1933, a który rzuca światło na aktywność duszpasterską i organizacyjną władz Polskiej Misji Katolickiej we Francji. Dokonuje wyraźnego rozróżnienia na listy, które rektor ks. Leon Łagoda kierował do wiernych, i okólniki, które były tekstami urzędowymi przeznaczonymi dla duchowieństwa. Osobną kategorię stanowią pisma adresowane np. do hierarchów kościelnych lub związane z obchodami uroczystości.
Tuberculosis Diagnostics and Susceptibility in Saudi Arabia’s Western Region
Authors: Qutub Mohammed , Wali Ghassan , Alraddadi Basem , Bahabri Nezar , Aldabbagh Yasser , Zaki Sara , Mehdawi Fahtima , Govindan Prasanth , Vattappillil Anupama , Alamoudi Ebtihal 
Published: November 2020

Introduction: Saudi Arabia has a moderate infection rate of tuberculosis (TB) in comparison to other countries in the region. The prevalence of TB varies among different parts of the Kingdom, with its western provinces reporting to have the leading rate of incidence.
Method : In this retrospective study, Acid-fast bacilli smear (AFB), and nucleic acid amplification test (NAAT) were performed on all positive cultures from 254 identified TB cases from November 2006 to August 2016 in King Faisal Specialist Hospital and Research Center – Jeddah, Saudi Arabia.
Results: From the positive cultures for Mycobacterium tuberculosis complex, 99.1% were found to be positive by using NAAT. From the NAAT positive samples, only 36.8% were positive for AFB. TB was predominant among the younger age group (59.4%) compared to the elderly population (35.8%) and pediatrics (4.7%), and it was also observed that males had a higher prevalence of 56.3 % in comparison to females. In regards to the site of infection, 53.1 % were pulmonary and 46.9% from an extrapulmonary. It was noted that resistance to first-line anti-TB drugs individually was found to be 11.0% to Streptomycin, 10.2% to isoniazid, 5.1% to pyrazinamide, 2.4% to Rifampicin, and 1.2% Ethambutol, yet multi-drug resistance (MDR) was found in 2.4% of observed cases.
Conclusion: Young age predominance, low direct smear positivity, increased incidence of the extrapulmonary site of infection, and re-emergence of TB resistance all were observed in our study compared to previous national surveys.
Using the Internationally Recognized Frameworks of Nursing Competences to address the challenges of nurse refugees without documentation
Authors: Cassar Maria 
Published: November 2020

Individuals seeking refuge in host countries is a global reality. Some of these individuals are qualified nurses. If, and when, the documents pertaining to a nurse qualification are not presented to the respective authorities of a host country, the challenges for these qualified nurses to secure registration and employment as nurses are numerous and often unsurmountable. Access to higher education opportunities is similarly compromised in the absence of relevant documents. This is happening against the backdrop of a widely reported global shortage of qualified nurses, and an extensive effort and investment to address this shortage in many countries. This paper explores the feasibility and appropriateness of applying internationally recognized frameworks of competences of nurses, to processes which seek to evaluate and verify the nurse training and qualification claimed by refugee nurses. The author seeks to determine whether such frameworks of nurse competences may effectively and efficiently contribute towards initiatives which are geared towards addressing the gap in (qualification) document availability, traceability, verification and reproduction of nurse refugees. A critical consideration of a few existent initiatives is presented in view of exploring, the identification of a tool which may enable a homogenous transnational approach which is consistent across salient parameters.
Received: 16 April 2020Accepted: 31 August 2020
Forecasting of recurrent atrial fibrillation after radiofrequency ablation of pulmonary veins using preoperative characteristics
Authors: Bondarenko B. B. , Grigoryeva A. V. , Sokolova L. A. , Bart V. A. , Gorlova I. A. , Ivanov S. Yu. , Omelchenko M. Yu. 
Published: November 2020

Background. Atrial fibrillation (AF) is the most frequent arrhythmia. The method of catheter radiofrequency ablation (CRA) of pulmonary veins (PV) does not guarantee the preservation of sinus rhythm. Determination of predictors of AF relapses dictates the need in systemic approach taking into account demographic and clinical-instrumental characteristics of patients.Objective. Determination of preoperative predictors of AF recurrence within 3 year after follow-up CRA PV.Design and methods. The study included 89 patients (50 men, 39 women; mean age 58 and 62 years respectively) followed during 3 years after CRA PV. The methods of principal components and discriminant analysis were used for analytical purposes.Results. The recurrence of AF was observed in 43 patients (48 %): during the first year — in 18 (43 %), during the second — in 16 (37 %), during the third — in 9 (20 %) cases. By consistently using the methods of descriptive and multivariant statistics a set of the preoperative indicators has been identified that distinguishes patients with AF relapses undergone CRA PV. It consists of the longivity of AF, the state of contractive myocardial function, the presence of ICD, cardioversion in the past and thyroid pathology. The contribution of modified risk factors: SBP level, BMI, tobacco smoking also are valued.Conclusion. Using of multivariant statistics allows to determine preoperative characteristics, which provide optimization of management of patients with AF.
Implementasi Konsep Kampung Tematik sebagai Solusi Permukiman Kumuh di Kauman Jember
Authors: Hartono Ilham Wahyu , Farhan Wafi , Hardiyanti Indy Farha Elya , Dwi Piping , Yoga Nanta Andra 
Published: November 2020

Permukiman kumuh adalah masalah kompleks yang sedang dihadapi oleh kota besar maupun berkembang. Secara umum, permukiman kumuh dapat dilihat dari kodisi fisik berupa bangunan, jaringan jalan, sistem drainase, dan pengelolaan sampah. Dilihat dari kondisi sosial ekonomi dimana tingkat kemisikinan dan angka pengangguran tinggi dan terjadi dampak berupa kondisi kesehatan, sumber penyebaran dan perilaku menyimpang. Munculnya kampung kota berawal dari masyarakat desa yang ingin meningkatkan perekonomianya dengan mencari pekerjaan ke kota. Salah satu kampung kota yang menarik untuk dibahas dan diteliti adalah Kauman Jember. Kauman Jember merupakan permukiman yang terletak di kawasan perkotaan Jembet tepatnya di daerah alun-alun. Kauman Jember merupakan salah satu kawasan yang mencirikan permukiman kumuh. Sehubungan dengan hal tersebut, kondisi lokasi penelitian mememiliki kesaamaan secara fisik dan histroris, Kampung Jodipan Malang memiliki karakteristik yang sama dengan Kampung Kauman, saat ini Kampung Jodipan menjadi kampung smarth living, sebelum menjadi kampung smart living kampung jodipan merupakan permukiman kumuh. Tujuan penelitian ini untuk mengetahui karakteristik kawasan permukiman kumuh yang terdapat di Kauman dan di korelasikan dengan karakteristik Kawasan Wisata Jodipan dahulu yang kemudian muncul sebuah konsep untuk mengatasi permasalahan kumuh di Kauman dan di korelasikan dengan karakteristik Kawasan Wisata Jodipan dahulu yang kemudian muncul sebuah konsep untuk mengatasi permasalahan kumuh di Kauman. Hasil yang ingin diperoleh dalam penelitian ini adalah untuk mengembangkan Kampung Kauman yang dijadikan kawasan wisata dapat diharapkan menjadi sumber dan potensi kegiatan ekonomi yang dapat dipercaya, termasuk kegiatan sektor lain sehingga lapangan pekerjaan, pendapatan masyarakat dan pendapatan daerah meningkat melalui upaya pengembangan kampung kauman menjadi kampung Tematik warna-warni.
Vaginismus and Infertility
Authors: Rossy Sintya Marthasari  , A. Marlinata  , Reny I’tishom  
Published: November 2020

Background: Vaginismus described as persistent or reccurent difficulties for woman to allow vaginal entry of a penis, a finger or there is often avoidance and anticipation, fear or experience of pain, along with variable involuntary contraction of pelvic muscle.
Reviews: Vaginismus can lead to unconsummated marriage, and also can be hidden caused of infertility. Vaginismus can be categorized as primary (lifelong), patient has never experiences non painful intercourse or secondary (acquired), patient has previously normal but now experience pain. Vaginismus should be considered as part of differential diagnosis in patient who has no satisfaction in sexual intercourse or do not tolerate penetration. Diagnosis is made by making a good history taking. A variety of intervention have been suggested in some case report study. Effective treatment to vaginismus include sex education, psychosexual therapy, systematic desensitization, anxiolytic and Botulinum Toxin (botox). While there are few controlled studies on the management of vaginismus, they are limited and poorly designed.
Summary: Goal of treatment is not only to achieve pregnancy but also increase quality of life. Either natural or assisted, vaginismus is still have to be cured. A great teamwork is required to successfull therapy.
Institutionalising wastewater surveillance systems to minimise the impact of COVID-19: cases of Indonesia, Japan and Viet Nam
Authors: Takeda T. , Kitajima M. , Huong N. T. T. , Setiyawan A. S. , Setiadi T. , Hung D. T. , Haramoto E. 
Published: November 2020

Abstract
This mini review describes the current status and challenges regarding institutionalisation of wastewater surveillance systems against COVID-19. Monitoring SARS-CoV-2 in wastewater has been proposed to be a potential tool to understand the actual prevalence of COVID-19 in the community, and it could be an effective approach to monitor the trend during the COVID-19 pandemic. However, challenges to institutionalise wastewater surveillance systems are still abundant and unfolding at a rapid rate given that the international understanding regarding the scientific knowledge and socio-political impacts of COVID-19 are in the developing stages. To better understand the existing challenges and bottlenecks, a comparative study between Japan, Viet Nam, and Indonesia was carried out in the present study. Through gaining a better understanding of common issues as well as issues specific to each country, we hope to contribute to building a robust multistakeholder system to monitor SARS-CoV-2 in wastewater as an effective disease surveillance system for COVID-19.
Pharmaceutical and Biomedical Applications of Green Synthesized Metal and Metal Oxide Nanoparticles
Authors: Zafar Nabila , Madni Ahmed , Khalid Ayesha , Khan Taous , Kousar Rozina , Naz Syeda Sohaila , Wahid Fazli 
Published: November 2020

Background:
Due to the rapid growth in life threatening diseases such as cancer, diabetes, chronic
wound and HIV/AIDS along with rise of side effects of the current treatments, world is now focusing to utilize
new treatment options. Currently, the development of green nanotechnology field seems as a potential alternate
for diseases diagnosis and treatment by preparation of various sizes and shapes of nanomaterials.

Objective:
This review is to present the explored biological sources in synthesis of nanomaterials particularly
metal and metal oxides nanoparticles and critical review of the applications of biosynthesized nanoparticles in
pharmaceutical and biomedical fields.

Methods:
In this review, the various biological sources including bacteria, fungi, algae and plants used in synthesis
of nanomaterials and mechanism involved in preparation are elaborated. In addition, biosynthesized nanomaterials
applied as drug delivery system for anticancer, antibiotic, antidiabetic agent and functioned as potential
diagnostic, antimicrobial, anticancer and wound healing candidates are comprehensively reviewed.

Results:
The synthesized metal and metal oxides from green protocol proved to have advantages such as being
biocompatible, effective and cheap. Furthermore, the green synthesized metal and metal oxide nanoparticles
showed to possess prominent physical, chemical and biological properties that can be efficiently utilized for
pharmaceutical and biomedical applications.

Conclusion:
The information gathered in this review will provide a baseline for exploring more potential usage of
green synthesized metal and metal oxide nanomaterials for various other applications. However, a concrete understanding
of the safety of these nanomaterials is still needed to minimize the potential side effects.
Can Host Cell Proteins Like ACE2, ADAM17, TMPRSS2, Androgen Receptor be the Efficient Targets in SARS-CoV-2 Infection?
Authors: Gupta Vivek K. , Murthy Madhan K. , Patil Shripad 
Published: November 2020

:
A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
-2), which caused a large disease outbreak in Wuhan, China in December 2019, is currently spreading
across the world. Along with binding of the virus spike with the host cell receptor, fusion of the
viral envelope with host cell membranes is a critical step in establishing successful infection of
SARS-CoV-2. In this entry process, a diversity of host cell proteases and androgen receptor play a
very important role directly or indirectly. These features of SARS-CoV-2 entry contribute to its
rapid spread and severe symptoms, high fatality rates among infected patients.

:
This review is based on the latest published literature including review articles, research articles,
hypothetical manuscript, preprint articles and official documents. The literature search was made
from various published papers on physiological aspects relevant to SARS-CoV and SARS-CoV-2.

:
In this report, we focus on the role of host cell proteases (ACE2, ADAM17, TMPRSS2) and androgen
receptor (AR) in SARS-CoV-2 infection. The hypotheses put forth by us are based on the role
played by the proteases ACE2, ADAM17, TMPRSS2 and AR in SARS-CoV-2 infection, which
were deduced based on various studies. We have also summarized how these host proteins increase
the pathology and the infective ability of SARS-CoV-2 and we posit that their inhibition may be a
therapeutic option for preventing SARS-CoV-2 infection.
Fenugreek Cultivation with Emphasis on Historical Aspects and its uses in Traditional Medicine and Modern Pharmaceutical Science
Authors: Sun Wenli , Shahrajabian Mohamad Hesam , Cheng Qi 
Published: November 2020

:
Fenugreek (Trigonella foenum-graecum L.) is a native plant found in the parts of Iran to the
North of India, and is presently planted also in other regions of the world. Fenugreek is considered a
notable multipurpose medicinal and traditional herb in Iran, India, and China for several centuries.
The most important components of fenugreek seeds are protein, neutral detergent fiber, gum, lipids,
moisture, ash and starch. Fenugreek seeds and leaves are anti-cholesterolemic, anti-tumor, antiinflammatory,
carminative, demulcent, deobstruent, emollient, expectorant, galactogogue, febrifuge,
laxative, hypoglycaemic, restorative, parasiticide and uterine tonic and useful in burning sensation.
Traditionally, fenugreek seeds being used worldwide are beneficial for bone and muscles, respiratory
system, gastro-intestinal system, female reproductive system, cardio-vascular system, endocrinology
and hepatic. Fenugreek helps reduce cholesterol, reduce cardiovascular risk, control diabetes, a good
consolation for sore throats, a remedy for acid reflux, constipation, colon cancer prevention, appropriate
for kidney trouble, skin infection, increase milk production, reduce menstrual discomfort, and reduce
menopause symptoms. It is also an appetite suppressant that helps in weight loss. Both modern
science and traditional medicine integration with novel technologies and discoveries will secure the
cultivation of medicinal herbs and promote sustainability in the long-term and a wide-range.