bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge translation of the Canadian 24-Hour Movement Guidelines for Adults aged 18–64 years and Adults aged 65 years or older: a collaborative movement guideline knowledge translation process
Authors: Tomasone Jennifer R. , Flood Stephanie M. , Latimer-Cheung Amy E. , Faulkner Guy , Duggan Mary , Jones Rebecca , Lane Kirstin N. , Bevington Frances , Carrier Julie , Dolf Matt , Doucette Kevin , Faught Emma , Gierc Madelaine , Giouridis Nicole , Gruber Reut , Johnston Nora , Kauffeldt Kaitlyn D. , Kennedy William , Lorbergs Amanda , Maclaren Kaleigh , Ross Robert , Tytler Kim , Walters Alexandra J. , Welsh Frank , Brouwers Melissa C. 
Published: October 2020

Establishing a step-by-step process that provides practitioners with a blueprint for translating movement guidelines into action stands to optimize the investment in guideline development, improve guideline promotion and uptake, and ultimately enhance population health. The purpose of this paper is to describe how the Knowledge-to-Action framework and integrated knowledge translation were operationalized to systematically inform our knowledge translation (KT) efforts for the Canadian 24-Hour Movement Guidelines for Adults aged 18–64 years and Adults aged 65 years or older. In October 2018, the need for a KT Process, operating in tandem with the Guideline Development Process, led to the establishment of a KT team with a specific structure and terms of reference. The KT team collaboratively agreed on decision-making principles prior to selecting target audiences to focus their efforts. We undertook formative research to assess the local context and determinants of guideline dissemination and implementation efforts among target audiences. Plans for the subsequent steps and research are outlined. We highlight recommendations and lessons learned for applying the process in other settings.Novelty We outline a collaborative and systematic process and research program for the knowledge translation of movement guidelines. This paper provides an innovative and replicable blueprint to optimize future movement guideline knowledge translation efforts.
Important Influence of Entrance Channel Reorientation Coupling on Proton Stripping
Authors: Keeley N. , Kemper K. W. , Rusek K. 
Published: October 2020

AbstractWhile it is well established that the ground state reorientation coupling can have a significant influence on the elastic scattering of deformed nuclei, the effect of such couplings on transfer channels has been much less well investigated. In this letter we demonstrate that the $$^{208}\hbox {Pb}(^7\hbox {Li},^6\hbox {He})^{209}\hbox {Bi}$$

208

Pb

(
7

Li

,
6

He
)

209

Bi

proton stripping reaction at an incident energy of 52 MeV can be well described by the inclusion of the $$^7\hbox {Li}$$

7

Li

ground state reorientation coupling within the coupled channels Born approximation formalism. Full finite-range distorted wave Born approximation calculations were previously found to be unable to describe these data. Addition of coupling to the 0.478-MeV $$1/2^-$$

1
/

2
-

excited state of $$^7\hbox {Li}$$

7

Li

, together with the associated two-step transfer path, has little or no influence on the shape of the angular distributions (except that for stripping leading to the 1.61-MeV $$13/2^+$$

13
/

2
+

level of $$^{209}\hbox {Bi}$$

209

Bi

which is significantly improved) but does affect appreciably the values of the $$^{209}\mathrm {Bi} \rightarrow {^{208}\mathrm {Pb}} + p$$

209

Bi
→

208

Pb

+
p

spectroscopic factors. Implications for experiments with weakly-bound light radioactive beams are discussed.
Distribution amplitudes of heavy mesons and quarkonia on the light front
Authors: Serna Fernando E. , da Silveira Roberto Correa , Cobos-Martínez J. J. , El-Bennich Bruno , Rojas Eduardo 
Published: October 2020

AbstractThe ladder kernel of the Bethe–Salpeter equation is amended by introducing a different flavor dependence of the dressing functions in the heavy-quark sector. Compared with earlier work this allows for the simultaneous calculation of the mass spectrum and leptonic decay constants of light pseudoscalar mesons, the $$D_u$$

D
u

, $$D_s$$

D
s

, $$B_u$$

B
u

, $$B_s$$

B
s

and $$B_c$$

B
c

mesons and the heavy quarkonia $$\eta _c$$

η
c

and $$\eta _b$$

η
b

within the same framework at a physical pion mass. The corresponding Bethe–Salpeter amplitudes are projected onto the light front and we reconstruct the distribution amplitudes of the mesons in the full theory. A comparison with the first inverse moment of the heavy meson distribution amplitude in heavy quark effective theory is made.
Nonlinear parabolic predator–prey coupled system with convection
Authors: Palencia José Luis Díaz , López Mariano Fernández 
Published: October 2020

The aim of this work is to provide a formulation of two related nonlinear diffusive convective models in the form of coupled reaction-absorption equations. First, the postulated models are studied with an analytical approach. Later on, numerical evidences are considered to account for a precise characterization. The problem ([Formula: see text]) analyzed is of the form: [Formula: see text] Afterwards, a related problem [Formula: see text] is studied: [Formula: see text] The principal aspects for analysis are related to the existence and the derivation of particular solutions to reproduce the dynamic of the interacting species. For the problem [Formula: see text], we make use of the TW approach to study existence of solutions and precise evolution of profiles. Note that the term predator is used to refer to an invasive behavior, while the term prey is used for the invaded species.
The Analysis of the Transformation Mechanism of cBN Crystals with the First-Principle Calculation
Authors: Cai Lichao , Xu Bin , Lv Meizhe , Fan Xiaohong 
Published: October 2020

To clarify the synthesis mechanism of cubic boron nitride (cBN) with catalysts at high temperature and high pressure, we calculate the surface energy of the main phases in the Li-N-B synthesis system using the first-principle method. Based on the density functional theory, the surface energy of low-index surfaces of cBN, hexagonal boron nitride (hBN), and lithium boron nitride (Li3BN2) at the cBN synthetic temperature of 1700 K and synthetic pressure of 5.0 GPa is calculated. The surface energy of the main low-index surfaces of cBN is σ (111) > σ (001) > σ (110), that of hBN is σ

10

1
¯

0

> σ

11

2
¯

0

> σ (0001), and that of Li3BN2 is σ (100) > σ (110) > σ (001). The energy orders of the main low-index surfaces were well contrary to the corresponding orders of the valence electron density of the low-index surfaces of cBN, hBN, and Li3BN2, which were calculated by the empirical electron theory (EET) of solids and molecules. The result shows that the calculation results in this paper are well consistent with the previous results of the EET theory and support for the results of the “direct transformation of hBN to cBN under the catalysis of Li3BN2” obtained by the EET theory.
Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2–SR-BI Axis
Authors: Ghaffari Siavash , Jang Erika , Naderinabi Farnoosh , Sanwal Rajiv , Khosraviani Negar , Wang Changsen , Steinberg Benjamin E. , Goldenberg Neil M. , Ikeda Jiro , Lee Warren L. 
Published: October 2020

Objective:
LDL (low-density lipoprotein) transcytosis across the endothelium is performed by the SR-BI (scavenger receptor class B type 1) receptor and contributes to atherosclerosis. HMGB1 (high mobility group box 1) is a structural protein in the nucleus that is released by cells during inflammation; extracellular HMGB1 has been implicated in advanced disease. Whether intracellular HMGB1 regulates LDL transcytosis through its nuclear functions is unknown.

Approach and Results:
HMGB1 was depleted by siRNA in human coronary artery endothelial cells, and transcytosis of LDL was measured by total internal reflection fluorescence microscopy. Knockdown of HMGB1 attenuated LDL transcytosis without affecting albumin transcytosis. Loss of HMGB1 resulted in reduction in SR-BI levels and depletion of SREBP2 (sterol regulatory element-binding protein 2)—a transcription factor upstream of SR-BI. The effect of HMGB1 depletion on LDL transcytosis required SR-BI and SREBP2. Overexpression of HMGB1 caused an increase in LDL transcytosis that was unaffected by inhibition of extracellular HMGB1 or depletion of RAGE (receptor for advanced glycation endproducts)—a cell surface receptor for HMGB1. The effect of HMGB1 overexpression on LDL transcytosis was prevented by knockdown of SREBP2. Loss of HMGB1 caused a reduction in the half-life of SREBP2; incubation with LDL caused a significant increase in nuclear localization of HMGB1 that was dependent on SR-BI. Animals lacking endothelial HMGB1 exhibited less acute accumulation of LDL in the aorta 30 minutes after injection and when fed a high-fat diet developed fewer fatty streaks and less atherosclerosis.

Conclusions:
Endothelial HMGB1 regulates LDL transcytosis by prolonging the half-life of SREBP2, enhancing SR-BI expression. Translocation of HMGB1 to the nucleus in response to LDL requires SR-BI.
Subaortic Membranes in Patients With Hereditary Hemorrhagic Telangiectasia and Liver Vascular Malformations
Authors: Kim Agnes S. , Henderson Katharine J. , Pawar Sumeet , Kim Min Jung , Punjani Shahnaz , Pollak Jeffrey S. , Fahey John T. , Garcia‐Tsao Guadalupe , Sugeng Lissa , Young Lawrence H. 
Published: October 2020

Background
Patients with hereditary hemorrhagic telangiectasia have liver vascular malformations that can cause high‐output cardiac failure (HOCF). Known sequelae include pulmonary hypertension, tricuspid regurgitation, and atrial fibrillation.

Methods and Results

The objectives of this study were to describe the clinical, echocardiographic, and hemodynamic characteristics and prognosis of hereditary hemorrhagic telangiectasia patients with HOCF who were found to have a subaortic membrane (SAoM). A retrospective observational analysis comparing patients with and without SAoM was performed. Among a cohort of patients with HOCF, 9 were found to have a SAoM in the left ventricular outflow tract by echocardiography (all female, mean age 64.8±4.0 years). The SAoM was discrete and located in the left ventricular outflow tract 1.1±0.1 cm below the aortic annular plane. It caused turbulent flow, mild obstruction (peak velocity 2.8±0.2 m/s, peak gradient 32±4 mm Hg), and no more than mild aortic insufficiency. Patients with SAoM (n=9) had higher cardiac output (12.1±1.3 versus 9.3±0.7 L/min,
P
=0.04) and mean pulmonary artery pressures (36±3 versus 28±2 mm Hg,
P
=0.03) compared with those without SAoM (n=19) during right heart catheterization. Genetic analysis revealed activin receptor‐like kinase 1 mutations in each of the 8 patients with SAoM who had available test results. The presence of a SAoM was associated with a trend towards higher 5‐year mortality during follow‐up.

Conclusions
SAoM with mild obstruction occurs in patients with hereditary hemorrhagic telangiectasia and HOCF. SAoM was associated with features of more advanced HOCF and poor outcomes.
Thetis in Identity Crisis
Authors: Alepidou Apostolia 
Published: October 2020

Abstract
This article focuses on Statius’ representation of Thetis in the Achilleid in comparison with her representation in the Iliad. Statius, it is argued, goes against the Homeric tradition, depicting the goddess with features opposite from those she possesses in Homer. Thetis, generally perceived as a modest and ladylike speaker in the Iliad, employs masculine-gendered rhetoric and becomes offensive in the Achilleid; paternal acts linked to Peleus in the Homeric tradition are in Statius’ poem undertaken by Thetis; Homer’s omniscient and powerful goddess is almost ridiculed in Statius: being obsessed with the impossible, i.e. Achilles’ salvation, she repeatedly fails to achieve a possible delay of his doom. Through this technique, Statius inverts Thetis’ traditional character, creating a heroine that fits perfectly in his unconventional epic of cross-dressing and role-play.
Emotions and Reactions regarding Use of Cemeteries/Crematoriums following Loss of a Companion Animal in Spain
Authors: Clemente-Ricolfe José-Serafín , González-Navarro Sergio 
Published: October 2020

Abstract
We present the results of our analysis of the sentiments of guardians in Spain following the death of a companion animal, as well as their potential use of cemeteries/crematoriums, based on a personal survey that was completed by 197 guardians. Factor analysis revealed the existence of three dimensions. The first focused on emotional reactions following a companion animal’s death. The second considered personal relationships that developed between guardians and their companion animals. Finally, the third focused on benefits or value offered by a companion animal. Four segments were obtained by cluster analysis. The largest segment had the strongest intention of using/reusing cemetery or cremation services (3.2 out of 5). It was also the only segment which placed value on emotional reactions upon a companion’s death. The results showed that a strong bond between guardians and companion animals was associated with a higher probability that burial or cremation services would be used.
Targum Jonathan to the Prophets and the Masoretic Cantillations
Authors: Kahana Miriam 
Published: October 2020

Abstract
This article compares the Targum with Masoretic cantillations. The comparison between the different reading traditions shows agreement in everything concerning the division between one verse and the next. Usually, there is agreement in the division within each verse as well, particularly when both the cantillations and the Targum respond to an ideological or exegetical problem in the text. Juxtaposing the cantillations and the Targum in this manner may also reveal aspects of the stages of development of these two interpretative tools in relation to one another. Comparing Targumim and Babylonian cantillations also strengthens the assessment that the Tiberian system of accents was influenced by the Targum in its division of the verses. In addition, examining the way each verse is divided shows how the Targum seems to prefer a subordinate structure even when it translates paratactic clauses.
The Detached Self: Investigating the Effect of Depersonalisation on Self-Bias in the Visual Remapping of Touch
Authors: Farmer Harry , Cataldo Antonio , Adel Nagela , Wignall Emma , Gallese Vittorio , Deroy Ophelia , Hamilton Antonia , Ciaunica Anna 
Published: October 2020

Abstract
There is a growing consensus that our most fundamental sense of self is structured by the ongoing integration of sensory and motor information related to our own body. Depersonalisation (DP) is an intriguing form of altered subjective experience in which people report feelings of unreality and detachment from their sense of self. The current study used the visual remapping of touch (VRT) paradigm to explore self-bias in visual–tactile integration in non-clinical participants reporting high and low levels of depersonalisation experiences. We found that the high-DP group showed an increased overall VRT effect but a no-self-face bias, instead showing a greater VRT effect when observing the face of another person. In addition, across all participants, self-bias was negatively predicted by the occurrence of anomalous body experiences. These results indicate disrupted integration of tactile and visual representations of the bodily self in those experiencing high levels of DP and provide greater understanding of how disruptions in multisensory perception of the self may underlie the phenomenology of depersonalisation.
Distinguishing Characteristics of Tornadic and Nontornadic Supercell Storms from Composite Mean Analyses of Radar Observations
Authors: Homeyer Cameron R. , Sandmæl Thea N. , Potvin Corey K. , Murphy Amanda M. 
Published: October 2020

AbstractAn improved understanding of common differences between tornadic and nontornadic supercells is sought using a large set of observations from the operational NEXRAD WSR-88D polarimetric radar network in the contiguous United States. In particular, data from 478 nontornadic and 294 tornadic supercells during a 7-yr period (2011–17) are used to produce probability-matched composite means of microphysical and kinematic variables. Means, which are centered on echo-top maxima and in a horizontal coordinate system rotated such that storm motion points in the positive x dimension, are created in altitude relative to ground level at times of peak echo-top altitude and peak midlevel rotation for nontornadic supercells and times at and prior to the first tornado in tornadic supercells. Robust differences between supercell types are found, with consistent characteristics at and preceding tornadogenesis in tornadic storms. In particular, the mesocyclone is found to be vertically aligned in tornadic supercells and misaligned in nontornadic supercells. Microphysical differences found include a low-level radar reflectivity hook echo aligned with and ~10 km right of storm center in tornadic supercells and displaced 5–10 km down-motion in nontornadic supercells, a low-to-midlevel differential radar reflectivity dipole that is oriented more parallel to storm motion in tornadic supercells and more perpendicular in nontornadic supercells, and a separation between enhanced differential radar reflectivity and specific differential phase (with unique displacement-relative correlation coefficient reductions) at low levels that is more perpendicular to storm motion in tornadic supercells and more parallel in nontornadic supercells.
Alternative Entry Points for Adaptation: Examples from Vanuatu
Authors: Westoby Ross , Clissold Rachel , McNamara Karen E. 
Published: October 2020

AbstractAs climate change accelerates, effective adaptation is an urgent and unavoidable priority. Bottom-up approaches such as community-based adaptation have been portrayed as the panacea. Recent studies are, however, highlighting the ongoing and inherent issues with normative “community” conceptualizations that assume a geographically bound, temporally fixed, and harmonious unit. Despite documentation on the negative impact these problematic assumptions can have on adaptation outcomes, adaptation at the community scale remains the preferred option for project delivery in highly exposed places such as the Pacific Islands region. More creative entry points that are less charged with problematic assumptions are needed at the local scale. This paper draws from three examples in Vanuatu to offer compelling alternative entry points for adaptation: 1) a rural technical college embedded within an Anglican mission village, 2) a whole-of-island approach, and 3) the “collective of vendors” at marketplaces. We offer hope by identifying ways to expand on and complement existing, restricted notions of community and, through this, to improve adaptation outcomes.
An 8 miRNA-Based Risk Score System for Predicting the Prognosis of Patients With Papillary Thyroid Cancer
Authors: Yi Wanwan , Liu Jin , Qu Shuping , Fan Hengwei , Lv Zhongwei 
Published: October 2020

Background: Dysregulation of microRNAs (miRNAs) in papillary thyroid cancer (PTC) might influence prognosis of PTC. This study is aimed to develop a risk score system for predicting prognosis of PTC. Methods: The miRNA and gene expression profiles of PTC were obtained from The Cancer Genome Atlas database. PTC samples were randomly separated into training set (n = 248) and validation set (n = 248). The differentially expressed miRNAs (DE-miRNAs) in the training set were screened using limma package. The independent prognosis-associated DE-miRNAs were identified for building a risk score system. Risk score of PTC samples in the training set was calculated and samples were divided into high risk group and low risk group. Kaplan-Meier curves and receiver operating characteristic (ROC) curve were used to assess the accuracy of the risk score system in the training set, validation set and entire set. Finally, a miRNA-gene regulatory network was visualized by Cytoscape software, followed by enrichment analysis. Results: Totally, 162 DE-miRNAs between tumor and control groups in the training set were identified. An 8 independent prognosis-associated DE-miRNAs, (including miR-1179, miR-133b, miR-3194, miR-3912, miR-548j, miR-6720, miR-6734, and miR-6843) based risk score system was developed. The area under ROC curve in the training set, validation set and entire set was all above 0.93. A miRNA-gene regulatory network involving the 8 DE-miRNAs were built and functional enrichment analysis suggested the genes in the network were significantly enriched into 13 pathways, including calcium signaling pathway and hedgehog signaling pathway. Conclusion: The risk score system developed this study might be used for predicting the prognosis of PTC. Besides, the 8 miRNAs might affect the prognosis of PTC via hedgehog signaling pathway and calcium signaling pathway.
Safety of a strategy combining D-dimer testing and whole-leg ultrasonography to rule out deep vein thrombosis
Authors: Fronas Synne G. , Jørgensen Camilla T. , Dahm Anders E. A. , Wik Hilde S. , Gleditsch Jostein , Raouf Nezar , Holst René , Klok F. A. , Ghanima Waleed 
Published: October 2020

Abstract
Guidelines for the diagnostic workup of deep vein thrombosis (DVT) recommend assessing the clinical pretest probability before proceeding to D-dimer testing and/or compression ultrasonography (CUS) if the patient has high pretest probability or positive D-dimer. Referring only patients with positive D-dimer for whole-leg CUS irrespective of pretest probability may simplify the workup of DVT. In this prospective management outcome study, we assessed the safety of such a strategy. We included consecutive outpatients referred to the Emergency Department at Østfold Hospital, Norway, with suspected DVT between February 2015 and November 2018. STA-Liatest D-Di Plus D-dimer was analyzed for all patients, and only patients with levels ≥0.5 µg/mL were referred for CUS. All patients with negative D-dimer or negative CUS were followed for 3 months to assess the venous thromboembolic rate. One thousand three hundred ninety-seven patients were included. Median age was 64 years (interquartile range, 52-73 years), and 770 patients (55%) were female. D-dimer was negative in 415 patients (29.7%) and positive in 982 patients (70.3%). DVT was diagnosed in 277 patients (19.8%). Six patients in whom DVT was ruled out at baseline were diagnosed with DVT within 3 months of follow-up for a thromboembolic rate of 0.5% (95% confidence interval, 0.2-1.2). A simple diagnostic approach with initial stand-alone D-dimer followed by a single whole-leg CUS in patients with positive D-dimer safely ruled out DVT. We consider this strategy to be a valuable alternative to the conventional workup of DVT in outpatients. This trial was registered at www.clinicaltrials.gov as #NCT02486445.