bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hearing Care Providers' Perspectives on the Utility of Datalogging Information
Authors: Saunders Gabrielle H. , Bott Anthea , Tietz Lukas H. B. 
Published: September 2020

Purpose
The aim of the study was to learn (a) how datalogging information is being used in clinical practice by hearing care providers (HCPs) in the United States and (b) HCPs' opinions about how information collected through the hearing aids could be broadened in clinical application.

Method
A mixed-method approach was undertaken consisting of an online quantitative survey and qualitative structured telephone interviews. Survey data were analyzed using descriptives and chi-square analyses. The interview data were transcribed and analyzed using inductive content analysis.

Results
In total, 154 HCPs completed the survey, of whom 10 also completed an interview. Survey data showed that most HCPs use datalogging for conventional applications, such as counseling and fine-tuning during a hearing aid trial. Interview data highlighted four additional desirable datalogging features: (a) data about the sound environment, (b) details about operational aspects of hearing aid use, (c) data about use and nonuse, and (d) automated diagnosis of a hearing aid malfunction. HCPs also envisaged using datalogging in novel ways, such as for demonstrating hearing aid value and supporting decision making.

Conclusions
Today, datalogging is primarily used as a tool for counseling clients about hours and patterns of hearing aid use and for troubleshooting and fine-tuning. However, HCPs suggested novel and more ambitious uses of datalogging such as for sending alerts about nonuse, for automated diagnosis of a hearing aid malfunction, and for helping the client in their decision making. It remains to be seen whether in the future these will be implemented into clinical practice.
Apsidal motion in the massive binary HD 152248
Authors: Rosu S. , Noels A. , Dupret M.-A. , Rauw G. , Farnir M. , Ekström S. 
Published: September 2020

Context. Apsidal motion in massive eccentric binaries offers precious information about the internal structure of the stars. This is especially true for twin binaries consisting of two nearly identical stars.
Aims. We make use of the tidally induced apsidal motion in the twin binary HD 152248 to infer constraints on the internal structure of the O7.5 III-II stars composing this system.
Methods. We build stellar evolution models with the code Clés assuming different prescriptions for the internal mixing occurring inside the stars. We identify the models that best reproduce the observationally determined present-day properties of the components of HD 152248, as well as their internal structure constants, and the apsidal motion rate of the system. We analyse the impact on the results of some poorly constrained input parameters in the models, including overshooting, turbulent diffusion, and metallicity. We further build “single” and “binary” GENEC models that account for stellar rotation to investigate the impacts of binarity and rotation. We discuss some effects that could bias our interpretation of the apsidal motion in terms of the internal structure constant.
Results. The analysis of the Clés models reveals that reproducing the observed k2 value and rate of apsidal motion simultaneously with the other stellar parameters requires a significant amount of internal mixing (either turbulent diffusion, overshooting, or rotational mixing) or enhanced mass-loss. The results obtained with the GENEC models suggest that a single-star evolution model is sufficient to describe the physics inside this binary system. We suggest that, qualitatively, the high turbulent diffusion required to reproduce the observations could be partly attributed to stellar rotation. We show that higher-order terms in the apsidal motion are negligible. Only a very severe misalignment of the rotation axes with respect to the normal to the orbital plane could significantly impact the rate of apsidal motion, but such a high misalignment is highly unlikely in such a binary system.
Conclusions. We infer an age estimate of 5.15 ± 0.13 Myr for the binary system and initial masses of 32.8 ± 0.6 M⊙ for both stars.
Accelerated particle beams in a 3D simulation of the quiet Sun
Authors: Frogner L. , Gudiksen B. V. , Bakke H. 
Published: September 2020

Context. Observational and theoretical evidence suggest that beams of accelerated particles are produced in flaring events of all sizes in the solar atmosphere, from X-class flares to nanoflares. Current models of these types of particles in flaring loops assume an isolated 1D atmosphere.
Aims. A more realistic environment for modelling accelerated particles can be provided by 3D radiative magnetohydrodynamics codes. Here, we present a simple model for particle acceleration and propagation in the context of a 3D simulation of the quiet solar atmosphere, spanning from the convection zone to the corona. We then examine the additional transport of energy introduced by the particle beams.
Methods. The locations of particle acceleration associated with magnetic reconnection were identified by detecting changes in magnetic topology. At each location, the parameters of the accelerated particle distribution were estimated from local conditions. The particle distributions were then propagated along the magnetic field, and the energy deposition due to Coulomb collisions with the ambient plasma was computed.
Results. We find that particle beams originate in extended acceleration regions that are distributed across the corona. Upon reaching the transition region, they converge and produce strands of intense heating that penetrate the chromosphere. Within these strands, beam heating consistently dominates conductive heating below the bottom of the transition region. This indicates that particle beams qualitatively alter the energy transport even outside of active regions.
Sleep of Wheelchair Rugby Athletes: Training, Rest and
Competition
Authors: Sanz-Milone Victor , Narciso Fernanda V. , da Silva Andressa , Misuta Milton , de Mello Marco Túlio , Esteves Andrea Maculano 
Published: September 2020

AbstractThe aim of this study was to evaluate the sleep-wake cycle of wheelchair rugby
athletes during the pre-season compared to in-season. Wheelchair Rugby athletes
wore an actigraph monitor during two respective 10-day periods: 1) pre-season
and 2) in-season, each of which comprised three training days, three rest days,
and four competition days, respectively. In addition, the players completed
questionnaires regarding sleepiness, subjective quality of sleep, and
chronotype, as well as the use of the sleep diary along with the actigraph
measurements (20 days). The wheelchair rugby athletes had poor subjective sleep
quality in both stages observed by sleep efficiency below 85% (ES 0.31)
and high score in the Pittsburgh questionnaire (effect size-ES 0.55), the
actigraphy results presented an increase of sleep latency (ES 0.47), and wake
after sleep onset (ES 0.42). When comparing the athlete’s routine, the
competition days, demonstrated a reduction in the total time of sleep and the
sleep efficiency, in addition to an increase in wakefulness after sleep onset
when compared with the training and rest periods. As a result, the wheelchair
rugby players did not describe a pattern of sleep-wake cycle during different
training phases, as well as poor sleep quality.
Crohnʼs Disease Exclusion Diet (CDED) als Alternative zur exklusiven Ernährungstherapie bei Kindern und Jugendlichen mit Morbus Crohn? Stellungnahme der Arbeitsgemeinschaften CEDATA und Ernährung/Diätetik/Ernährungsmedizin der Gesellschaft für pädiatrische Gastroenterologie und Ernährung e. V.
Authors: de Laffolie Jan , Schwerd Tobias , Simon Annette , Pauli Maren , Broekaert Ilse , Classen Martin , Posovszky Carsten , Schmidt-Choudhury Anjona ,   im Namen und Auftrag der AGs CEDATA und AG Ernährung und Diätetik/Ernährungsmedizin der GPGE
Published: September 2020

ZusammenfassungEpidemiologische und klinische Beobachtungen sowie Tiermodelle weisen auf die Ernährung als Risikofaktor für die Entwicklung einer chronisch entzündlichen Darmerkrankung (CED) hin. Die exklusive enterale Ernährungstherapie (EET) ist das Musterbeispiel einer effektiven Entzündungskontrolle durch eine rein diätetische Intervention. Ausgehend davon haben Patienten, Familien und betreuende Fachkräfte des Gesundheitswesens ein großes Interesse, andere Ernährungsmodifikationen in der Behandlung von CED-Patienten einzusetzen, zum Beispiel eine partielle Ernährungstherapie (PET) mit spezifischer Diät wie die Crohnʼs Disease Exclusion Diet. Die folgende Stellungnahme fasst die aktuelle Datenlage zusammen und gibt Orientierung für Praxis und weitere Forschung.
Unexpected Inversion of Configuration During the Carbamoylation of 1-Azaflavaglines
Authors: Désaubry Laurent , Abou-Hamdan Hussein 
Published: September 2020

AbstractThe acylation of 8-demethoxy-1-azaflavaglines by dimethylcarbamoyl chloride was found to operate with an inversion of configuration, which is rationalized by the occurrence of styrylurea intermediate. The configuration-reversed products were not observed when the substrate was substituted by a methoxy in position 8, suggesting that an overstabilization of the carbocationic intermediate prevents this reaction to take place.
Expanding Uses of HIPEC for Locally Advanced Colorectal Cancer: A European Perspective
Authors: Cortes-Guiral Delia , Glehen Olivier 
Published: September 2020

AbstractLocally advanced colorectal cancer is a challenge for surgeons and medical oncologist; 10 to 20% colorectal cancer debut as locally advanced disease, with tumors extending through the colon wall with perforation and/or invasion of adjacent organs or structures. Those locally advanced tumors have a worse prognostic at any stage due not only to systemic dissemination but also in a high percentage of patients, to locoregional recurrence, in fact, peritoneal carcinomatosis of colorectal origin is so predictable that we can assess the risk for each patient according to some histopathological and clinical features: small peritoneal nodules resected in the first surgery (70% probability), ovarian metastases (60%), perforated tumor onset or intraoperative tumor rupture (50%), positive cytology (40%), and pT4/mucinous pT3 up to 40%. Prophylactic or adjuvant hyperthermic intraperitoneal chemotherapy seems to be a promising strategy for patients with advanced colorectal cancer to prevent the development of peritoneal recurrence and improve prognosis of this group of patients.
Multivisceral Resection of Advanced Pelvic Tumors: From Planning to Implementation
Authors: Mirnezami R. , Mirnezami A. 
Published: September 2020

AbstractPelvic exenteration involves radical multivisceral resection for locally advanced and recurrent pelvic tumors. Advances in tumor staging, oncological therapies, preoperative patient optimization, surgical techniques, and critical care medicine have permitted the safe expansion of pelvic exenterative surgery at specialist units. It is now understood that in carefully selected patients, 5-year survival can exceed 60% following pelvic exenteration, and that very low mortality figures and an optimum postexenteration quality of life are possible. In the present review, we provide a contemporary summary of the current state of the art in pelvic exenterative surgery following all key phases of the treatment pipeline from patient staging and tumor assessment, to treatment planning and surgery.
Impact of Nonclinical Factors on Treatment Decisions: What Can and Cannot Be Done and Why?
Authors: Sweney Matthew T. 
Published: September 2020

AbstractThis clinical scenario describes a situation where drug-resistant focal epilepsy could have been treated with specific surgery, but a mixture of nonclinical factors led to a different management. The epilepsy started at the age of 6 years and the assessment for other treatment options by this team was done at the age of 12 years. Financial factors were important in the decisions that had to be made and effectively perhaps decisive.
Diagnosis is in the Eye of the Beholder: Barriers to Early Diagnosis of Mucopolysaccharidosis in Children in India
Authors: Grewal Meenu , Muranjan Mamta 
Published: September 2020

AbstractThe present study examined referral pattern and diagnostic practices for mucopolysaccharidosis (MPS) in India in 40 patients with a confirmed diagnosis. Time lag between age of onset of symptoms and consultation with primary physician ranged from 0 to 84 months, between consultation with primary physician and visit to genetic clinic of 0 to 128 months, from visit to genetic clinic and diagnosis of 1 to 111 months, and that between onset of symptoms and diagnosis 1 to 154 months. Major causes for delayed diagnosis were symptoms overlooked by physician (54%), late consultation by care giver (48.6%), late onset of symptoms (43.2%), and resource crunch (32.4%). Diagnosis at referral other than MPS was noted in 45%. Thus, diagnostic delay for MPS is common due to health seeking practices of parents, as well as physicians' clinical practices. Overcoming these barriers would necessitate strengthening awareness and educational activities for physicians and lay public.
Comparison of Hirschsprung Disease Characteristics between Those with a History of Postoperative Enterocolitis and Those without: Results from the Pediatric Colorectal and Pelvic Learning Consortium
Authors: Taylor Mark A. , Bucher Brian T. , Reeder Ron W. , Avansino Jeffrey R. , Durham Megan , Calkins Casey M. , Wood Richard J. , Levitt Marc A. , Drake Kaylea , Rollins Michael D. 
Published: September 2020

Abstract
Introduction The current understanding of Hirschsprung-associated enterocolitis (HAEC) is based mainly on single-center, retrospective studies. The aims of this study are to determine risk factors for postoperative HAEC using the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) database.
Materials and Methods We performed a multicenter, retrospective, case–control study of children with Hirschsprung disease (HD) who had undergone a pull-through procedure and were evaluated at a PCPLC member site between February 2017 and March 2020. The cohort with a history of postoperative HAEC was compared with that without postoperative episodes of HAEC to determine relevant associations with postoperative HAEC.
Results One-hundred forty of 299 (46.8%) patients enrolled had a history of postoperative HAEC. Patients with a rectosigmoid transition zone had a lower association with postoperative HAEC as compared with those with a more proximal transition zone (odds ratio [OR]: 0.46, 95% confidence interval [CI]: 0.26, 0.84, p < 0.01). Private insurance was protective against postoperative HAEC on univariate analysis (OR: 0.62, 95% CI: 0.38, 0.99, p = 0.047), but not on multivariate analysis (OR: 0.62, 95% CI: 0.37, 1.04, p = 0.07). Preoperative HAEC was not associated with the development of postoperative HAEC.
Conclusion Patients with a rectosigmoid transition zone have less postoperative HAEC compared with patients with a more proximal transition zone. Multi-institutional collection of clinical information in patients with HD may allow for the identification of additional risk factors for HAEC and afford the opportunity to improve care.
Computational generation of an annotated gigalibrary of synthesizable, composite peptidic macrocycles
Authors: Saha Ishika , Dang Eric K. , Svatunek Dennis , Houk Kendall N. , Harran Patrick G. 
Published: September 2020

SignificanceWe describe computations to anticipate products of multistep reaction sequences. The work is based on experimental methods developed earlier to amalgamate synthetic scaffolding reagents with small linear peptides. Hybrid products retain molecular recognition elements in the peptide, but display that functionality as part of amphipathic macrocycles having defined conformations and improved pharmacological properties. The hypothetical scope of the chemistry is large and far outpaces the experimental format. To explore the structure space more extensively, we devised algorithms to predict outcomes of more than 2 billion processing sequences. Software was also developed to generate accurate three-dimensional structures for each product. The resultant virtual library is a resource that can be deployed broadly in search of novel ligands for protein receptors.
Detection of SARS-CoV-2 in a cat owned by a COVID-19−affected patient in Spain
Authors: Segalés Joaquim , Puig Mariona , Rodon Jordi , Avila-Nieto Carlos , Carrillo Jorge , Cantero Guillermo , Terrón Maria Teresa , Cruz Sílvia , Parera Mariona , Noguera-Julián Marc , Izquierdo-Useros Nuria , Guallar Víctor , Vidal Enric , Valencia Alfonso , Blanco Ignacio , Blanco Julià , Clotet Bonaventura , Vergara-Alert Júlia 
Published: September 2020

Significance
COVID-19 is the most devastating pandemic in recent history. As with many emerging infectious diseases, it is of zoonotic origin, meaning that animals played a major role in the initial transmission events. Despite SARS-CoV-2 being highly adapted to jump from human to human, several animal species are naturally susceptible to SARS-CoV-2, including pets such as cats. In the present report, a cat from a family with several relatives affected by COVID-19 developed severe respiratory clinical signs, leading to humanitarian euthanasia. Due to the suspicion of a potential COVID-19 infection in the cat, different antemortem and postmortem tests were assayed. The clinical condition was finally attributed to a feline hypertrophic cardiomyopathy, but the animal was also infected by SARS-CoV-2.
Some reflections on semantic–pragmatic cycles
Authors: Pons Bordería Salvador , Llopis Cardona Ana Belén 
Published: September 2020

AbstractThis paper explores novel ways to consider semantic–pragmatic cycles using a dual strategy: an inwards strategy, whereby the distinctive traits of a pragmatic cycle are established, and an outwards strategy, whereby the categories that delimit semantic–pragmatic cycles are described. The result of this exploration is the distinction between “pragmatic cycle”, “replication”, “concomitance” and “paradigmatic increase” as four different yet related processes. In addition, this study integrates Construction Grammar into the description of each process and shows that the study of semantic–pragmatic cycles can benefit from a constructional approach, adoptingTraugott and Trousdale’s (2013)andTraugott’s (2018)models, and including concepts from European structuralism, particularly the notions of “paradigm”, “diasystem” and “functional language” (“lengua funcional”).
A note on causality conditions on covering spacetimes
Authors: Costa e Silva Ivan P , Minguzzi Ettore 
Published: September 2020

Abstract
A number of techniques in Lorentzian geometry, such as those used in the proofs of singularity theorems, depend on certain smooth coverings retaining interesting global geometric properties, including causal ones. In this note we give explicit examples showing that, unlike some of the more commonly adopted rungs of the causal ladder such as strong causality or global hyperbolicity, less-utilized conditions such as causal continuity or causal simplicity do not in general pass to coverings, as already speculated by one of the authors (EM). As a consequence, any result which relies on these causality conditions transferring to coverings must be revised accordingly. In particular, some amendments in the statement and proof of a version of the Gannon–Lee singularity theorem previously given by one of us (IPCS) are also presented here that address a gap in its original proof, simultaneously expanding its scope to spacetimes with lower causality.
Schrödinger’s original quantum–mechanical solution for hydrogen
Authors: Galler Anna , Canfield Jeremy , Freericks James K 
Published: September 2020

Abstract
In 1926, Erwin Schrödinger wrote a series of papers that invented wave mechanics and set the foundation for much of the single-particle quantum mechanics that we teach today. In his first paper, he solved the Schrödinger equation using the Laplace method, which is a technique that is quite powerful, but rarely taught. This is unfortunate, because it opens the door to examining quantum mechanics from a complex-analysis perspective. Gaining this experience with complex analysis is a useful notion to consider when teaching quantum mechanics, as these techniques can be widely used outside of quantum mechanics, unlike the standard Frobenius summation method, which is normally taught, but rarely used elsewhere. The Laplace method strategy is subtle and no one has carefully gone through the arguments that Schrödinger did in this first paper, instead it is often just stated that the solution was adopted from Schlesinger’s famous differential equation textbook. In this work, we show how the Laplace method can be used to solve for the quantum–mechanical energy eigenfunctions of the hydrogen atom, following Schrödinger’s original solution, with all the necessary details, and illustrate how it can be taught in advanced instruction; it does require familiarity with intermediate-level complex analysis, which we also briefly review.
Approximate bright-soliton solution of the higher-order nonlinear Schrödinger equation
Authors: Meng De-Xin , Hu Ming-Yu , Xu Tao 
Published: September 2020

Abstract
In this paper, approximate bright-soliton solutions of the higher-order nonlinear Schrödinger equation are constructed by treating the higher-order terms as small perturbations. The first-, second-, and third-order asymptotic solutions are obtained. The errors between the asymptotic solutions and the numerical/analytical solutions are discussed, which gives a high accuracy of the approximate solutions. It is pointed that the asymptotic solutions can be used as the initial value to improve the accuracy of the numerical solutions. This paper may be helpful for undergraduate and graduate students in mathematics and physics to understand the approximate soliton solutions of the higher-order nonlinear Schrödinger equation.
Anomalous Hall transport in tilted multi-Weyl semimetals
Authors: Menon Anirudha , Basu Banasri 
Published: September 2020

Abstract
We study the effect of a perpendicular magnetic field B on a multinode Weyl semimetal (mWSM) of arbitrary integer monopole charge n, with the two Weyl multinodes separated in k-space. Besides type-I mWSMs, there exist type-II mWSMs which are characterized by the tilted minimal dispersion for low-energy excitations; the Weyl points in type-II mWSMs are still protected crossings but appear at the contact of the electron and hole pockets, after the Lifshitz transition. We find that the presence of a perpendicular magnetic field quantizes the occupation pockets due to the presence of Fermi tubes. In this theory, the Hilbert space is spanned by a set of n chiral degenerate ground states, and a countably infinite number of particle-hole symmetric Landau levels (LLs). We calculate the Hall conductivity for the tilt-symmetric case of type-I mWSM using the Kubo formula, in the zero-frequency (DC) limit, and recover the well-known vacuum contribution. We compute the Fermi surface corrections and show that the expression generalizes from the formula for elementary (n = 1) type-I WSMs. We derive an expression for the type-II mWSM Hall conductivity, which is bounded by a LL cutoff introduced on physical grounds. Interestingly, we find that the anomalous vacuum Hall conductivity is vanishing in the type-II phase at all temperatures. The corresponding thermal Hall and Nernst conductivities are evaluated and characterized for both phases. The qualitative and quantitative observations presented here may serve in the characterization of generic mWSMs of both types.