bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simplified and improved fluid deprivation test for diagnosing diabetes insipidus
Authors: Sjöström Anna , Bartuseviciene Inga , Höybye Charlotte 
Published: October 2020

Objective
The challenge of finding patients with the rare conditon of diabetes insipidus in need of vasopressin treatment is demanding. The guidelines for performing the fluid deprivation test and interpreting the results are abundant. We evaluated the discriminative capacity of the fluid deprivation test in patients with polyuria to define a cut off for a more effective discrimination between diabetes insipidus and other polyuria syndromes.

Research design and methods
Retrospective review and data collection of all ambulatory fluid deprivation tests, of patients with mild polyuria and polydipsia (< 3 L/day), performed between 2000 and 2018. Serum osmolality, urine osmolality, urine volumes and clinical information of diagnosis were retrieved from the patient’s medical records.

Results
The study group consisted of 153 patients, 123 were diagnosed with non-diabetes insipidus and 30 with diabetes insipidus. After 12 h fasting (baseline) median duration of the fluid deprivation test was 5 h (fasting range: 12–21 h). At baseline, there was a significant difference between median serum and urine osmolality between the groups (P < 0.05). The best cut-off for the diagnosis of diabetes insipidus, was the combination of < 400 mosmol/kg in urine and > 302 mosmol/kg in serum. With this cut-off a sensitivity of 90% and specificity of 98% was achieved.

Conclusion
After 12 h fasting our proposed cut off clearly differentiated between diabetes insipidus, and non-diabetes insipidus suggesting a possibility to considerably reduce the duration of the fluid deprivation test.
Taming of the Tiger: A Novel Technique to Deal With Mitral Annular Calcification —A Case Series
Authors: Panicker Varghese , Sreekantan Renjith , Kotera Sai Suraj 
Published: October 2020

Background: Mitral valve surgery can be challenging for patients with mitral annular calcification (MAC). The prevalence of MAC in patients who undergo mitral valve replacement is 19.9%. The treatment options for MAC include complete decalcification and annular reconstruction with valve repair/replacement or performing a surgical valve repair or replacement without decalcification, accepting the risk of paravalvular leak. We describe three cases of mitral valve prolapse with posterior annular calcification, which were repaired using a unique technique that does not require decalcification.
Case reports: The mitral annular calcification was heavy and involved most of the posterior annulus just sparing the commissures in all the three cases. Leaflet prolapse was dealt with by using neochordae, closing any clefts, and leaflet plication. Since the MAC ring was not complete and there was chance of further dilatation of the annulus, a partial annuloplasty was done using a PTFE felt (cut as strip). There was trivial to no mitral regurgitation with this technique in the immediate postoperative and five-year follow-up period echocardiography in all the three cases.
Conclusion: This technique can benefit the major subset of pure mitral valve regurgitant lesions associated with MAC, which is limited to the posterior annulus.
A Genome-Wide RNAi Screen for Enhancers of a Germline Tumor Phenotype Caused by Elevated GLP-1/Notch Signaling inCaenorhabditis elegans
Authors: Dalfó Diana , Ding Yanhui , Liang Qifei , Fong Alex , Cipriani Patricia Giselle , Piano Fabio , Zheng Jialin C , Qin Zhao , Hubbard E Jane Albert 
Published: October 2020

AbstractStem cells are tightly controlled in vivo. Both the balance between self-renewal and differentiation and the rate of proliferation are often regulated by multiple factors. The Caenorhabditis elegans hermaphrodite germ line provides a simple and accessible system for studying stem cells in vivo. In this system, GLP-1/Notch activity prevents the differentiation of distal germ cells in response to ligand production from the nearby distal tip cell, thereby supporting a stem cell pool. However, a delay in germline development relative to somatic gonad development can cause a pool of undifferentiated germ cells to persist in response to alternate Notch ligands expressed in the proximal somatic gonad. This pool of undifferentiated germ cells forms a proximal tumor that, in adulthood, blocks the oviduct. This type of “latent niche”-driven proximal tumor is highly penetrant in worms bearing the temperature-sensitive weak gain-of-function mutation glp-1(ar202) at the restrictive temperature. At the permissive temperature, few worms develop tumors. Nevertheless, several interventions elevate the penetrance of proximal tumor formation at the permissive temperature, including reduced insulin signaling or the ablation of distal-most sheath cells. To systematically identify genetic perturbations that enhance proximal tumor formation, we sought genes that, upon RNAi depletion, elevate the percentage of worms bearing proximal germline tumors in glp-1(ar202) at the permissive temperature. We identified 43 genes representing a variety of functional classes, the most enriched of which is “translation”. Some of these genes also influence the distal germ line, and some are conserved genes for which genetic interactions with Notch were not previously known in this system.
“Fat Cats on Golden Parachutes” – about an Idiom Derived from the Language of Politics and its Modifications
Authors: Połowniak-Wawrzonek Dorota , Rosińska-Mamej Agnieszka 
Published: October 2020

Due to the influence of the language of politics, the noun phrase, tłuste koty, has become established in modern Polish language. As the research material proves, the idiom fat cats has a negative connotation in the Polish language. Most often, it refers to rich people associated with business, as well as politicians and people in power, such as legislative, executive and judicial. The analysed texts provide many modifications of the expression under analysis, e.g., wypasione pisowskie tłuste koty, tłuste koty w sutannach, tłuste koty nadziane ośmiorniczkami, tłuste koty na złotych spadochronach, lejące krokodyle łzy podczas ucieczki z pogromu kociego na Wall Street, najtłustszy i wredny kot, okrąglutki, milutki, taki kotek tłuściutki. The most important function of modification is to express a critical opinion about people in the category of fatty cats. Through modifications, it is emphasized that the earnings of fatty cats are indecently high, often unreasonable and undeserved. Sharp social opposition causes financiers and politicians to avoid being responsible for their mistakes, for dishonesty. Fat cats are also accused of greed.
Expression of Conflict Communication in the Discourse of Presidential Election in Lithuania (2019)
Authors: Linkevičiūtė Vilma 
Published: October 2020

The subject matter of the article is different linguistic means of political conflict communication proper to the presidential discourse in Lithuania (2019). The research deals with the conflict communication of the three most popular candidates (according to sociological surveys) – G. Nausėda, S. Skvernelis, and I. Šimonytė. The political discourse of all three candidates is aimed at а positive self-representation; direct or indirect imputations of lack of sustained political commitment from the former president or their political opponents; accusation of pursuing their personal interests, or even making detrimental actions to the state and the society. The most prevalent meaning field in Nausėda’s discourse is welfare – detriment where THEY (former presidents, political parties and their representatives) are granted negative nominations, which are contrasted to positive nominations related to the latter candidate. The most prevailing meaning field in Skvernelis’s discourse is active and responsible state – inactive and irresponsible state which is expressed with the help of two sets of oppositions I – SHE (Grybauskaitė) and I – THEY (Parliamentary opposition and former political majority). The most popular meaning field in Šimonytė’s discourse is welfare – detriment, expressed with the help of I – THEY (members of the Lithuanian Farmers and Greens Union) opposition.
The Cartography of Love in Doris Lessing’s “love, again”
Authors: Miroshnychenko Lilia 
Published: October 2020

In her late novel, love, again (1996), Doris Lessing represents a penetrative insight of love, providing the widest perspective of love than in any of her previous work. The abundance and variety of plausible les affaires d’amour, which transgress the boundaries of gender, age, geography, and social status, make love, again Lessing’s most “loveful” novel. The narrative responds to this multiplicity accordingly. The essay explores the theme of romantic love of the central female character, Sarah Durham, who is at the centre of the narrative and whose emotional landscape is meticulously mapped. It also aims to unveil the ways Doris Lessing exploits a longstanding tradition of interpreting love in Western philosophy and culture – from Plato to contemporary theorists, including Alain Badiou. Special attention is paid to the interweaving of love and friendship in the relationship of woman and man as well as friendship’s “healing” power for unrequited love encapsulated in the character of Stephen Ellington-Smith. Also, by tracing the transformative impulse of love, the essay tries to bring light on the constructive (in the case of Sarah) and problematic (Stephen) consequences of love.
“Apple Blossoms” and “The Apple Tree”: Two Perspectives Typological and Ideological Similarities in Short Stories by Mykhailo Kotsiubynsky and John Galsworthy
Authors: Halchuk Oksana 
Published: October 2020

The article provides comparative analysis of Apple Blossoms by Mykhailo Kotsiubynsky and The Apple Tree by John Galsworthy. Both authors explore human morality in a crisis of confrontation between sensuality and death, the beauty of life and the beauty of art. At the structural level, the works share an element of paratext, novelistic nature, polysemic images-landscapes, and methods of psychologization. Galsworthy engages the antinomy of the city – province, resorts to irony, and combines elements of impressionist writing with the traditions of realistic socio-psychological prose. In contrast, Kotsiubynsky systematically implements the impressionist fragmentary nature of the composition, symbolism of visual and auditory images, in-depth psychoanalysis, and the conventionality of the chronotope.
The issues of short stories are diversified and aesthetic – as is distinct for modernist literature – implicitly in Kotsiubynsky’s work, and most explicitly through the connections with the Antiquity and English intertext in Galsworthy’s prose.
PENGEMBANGAN BAHAN AJAR BERBASIS KOMPETENSI MATAKULIAH MATEMATIKA SEKOLAH I
Authors: Putri Finola Marta 
Published: October 2020

Penelitian ini bertujuan untuk (1) menghasilkan bahan ajar berbasis kompetensi matakuliah Matematika Sekolah I sesuai tuntutan kurikulum yang berlaku di jurusan Pendidikan Matematika FITK UIN Syarif Hidayatullah Jakarta, dan (2) mendeskripsikan hasil validasi isi bahan ajar yang telah dikembangkan. Penelitian ini berupa penelitian pengembangan model 4-D yang terdiri atas empat tahap yaitu pendefenisian, perancangan, pengembangan, dan penyebaran. Pengumpulan data menggunakan: (1) teknik kepustakaan untuk mengembangkan bahan ajar, dan (2) teknik angket tertutup dan terbuka untuk mengumpulkan data kevalidan bahan ajar yang diedarkan kepada validator. Pengisian angket menggunakan skor 1, 2, 3, dan 4 serta menggunakan: (1) rentang 3,00 ≤
PROCESS ORIENTED GUIDED INQUIRY LEARNING, PEMBELAJARAN VAN HIELE, DAN KETERKAITANNYA
Authors: Hardianti Desrina , Desmayanasari Dwi , Noprisa Noprisa 
Published: October 2020

This research is a descriptive research. The purpose of this research was to analyze the relationship between POGIL model and van Hiele learning in an effort to increase the level of students' geometrical thinking. This research was implemented in one of junior high school in Bandung. The population in this research was grade VII students. The sample consisted of 63 students. Data level of students' geometrical thinking obtained through test techniques. Test questions are arranged based on indicators from each level. The data collection technique was carried out using the triangulation method. The data analysis technique was descriptive. Steps in this research are identifying the problem, reviewing the literature, arranging the instrument, collecting the data, analyzing the data and making the conclussion. This research shows the relation betwenen POGIL model and van Hiele Learning. They are (1) engage dan elicit steps in POGIL discribes inquiry step in van Hiele learning, (2) explore step discribes direct orientation step, (3) explanation step discribes explication step, (4) elaborate & extend steps discribes orientation step, (4) evaluation step discribes integration step.
KECEMASAN MATEMATIKA DAN KEMAMPUAN BERPIKIR KRITIS MATEMATIS SISWA DI SEKOLAH MENENGAH PERTAMA
Authors: Hadi Faiq Zulfikar , Fathurrohman Maman , Hadi Cecep Anwar 
Published: October 2020

This research is conducted by the low mathematics critical thinking ability of students in junior high schools, especially in VII grade .Students of VII grade commonly are transitioning from elementary school to junior high school could be a reason how low students of VII grade on mathematic critical thingking ability. The low ability mathematics critical thingking one of caused by mathematics anxiety. This study aims to find a relationship between math anxiety and mathematics critical thinking ability of VII grade at SMPN 5 Serang City. The method of this research is quantitative descriptive by making 110 students from VII grade as a sample. The data were collected using questionnaire and test. The result of this study indicate that 1) the ammount of correlation between math anxiety with critical thingking ability is -0,5991> rs table 0,1695, which means there is a significant and negative relationship between anxiety and critical thingking ability 2) the average of students’s mathematics critical thingking ability is different where score between students with low anxiety have a better score than student with mid anxiety and low anxiety,and students with mid anxiety have a better score than students with high anxiety, and students with mid anxiety have a better score than students with high anxiety.
Opanasenko N. Е. Skeletal soils and fruit cultures. – Kherson, 2014. – 335 p.
Authors: Travleyev A. P. , Bilova N. A. 
Published: October 2020

A number of slices of roots of fruit and nut cultures are thoroughly analysed in the paper. The architectonic schemes of plant root system along the profile are presented. In the gardens for the each breed of the growing cultures the test indexes of terms of their optimal growing are given, namely on the dense underlying rocks, in plantaged conditions, in the conditions of buried humus horizons. The power of root systems is examined, depending on the degree of fine earth and humus reserves. The scale of stability growth for the cultural garden plants of Crimea and many other indexes are set: water content in leaves, water intensity of leaves, real water deficit, water loss of leaves, indexes of the productivity, statistical indexes, productivity on the rootstock, hydrothermal coefficients, description of the south black earth, possible and optimal parameters of the power of the root layer, productivity on black earth, description of the foothill ordinary black earth, indices of growth and productivity. All data of the grown trees, fruit and fruit and berry cultures pass a statistical treatment with the information about the indexes of the trees’ growth and productivity dependence from the properties of the skeletal soils. At the end of the chapter the theoretical conclusions and the direct recommendations for the practical workers of garden economy are given.
Motor Skills in the Structure of Physical Fitness of 7-Year-Old Boys
Authors: Ivashchenko Olha , Berezhna Hanna , Cieślicka Mirosława 
Published: October 2020

The purpose of this study was to determine the weight of motor skills in the structure of motor fitness of 7-year-old boys. Materials and methods. The study participants were 38 7-year-old boys. The children and their parents were informed about all the features of the study and gave their consent to participate in the experiment. The research methods used in the study include analysis of scientific and methodological literature, pedagogical observations, testing of motor fitness, probabilistic approach to assessing the learning process, methods of mathematical statistics. Results. The level of fitness of the 7-year-old boys is homogeneous by the development of “agility” and “movement coordination”, inhomogeneous – by the development of arm strength and vestibular stability. The 7-year-old boys’ motor fitness is determined by their physical development, the level of general physical fitness and the level of motor skills development. A graphic representation of a two-factor model of testing results shows that analysis identifies two sets of data with high correlation coefficients. The first set includes tests No. 2, 1, 4, and 5, which characterize physical development, agility and endurance; the second – the level of proficiency in exercises No. 14, 13, 12, and the result of test No. 7 “Mixed hang rope pull-ups”. Conclusions. Based on factor analysis, the study found that the level of proficiency in exercises determines the variation of testing results by 28.437%, and the development of motor skills is a priority in the educational process at primary school. The development of “agility” and “movement coordination” ensures the formation of motor skills, and the development of arm strength and vestibular stability is the reserve in training boys aged 7 which will make it possible to increase the effectiveness of the educational process.
Comparative Analysis of Motor and Functional Fitness of 6th Grade Boys of an Underfilled School Under Quarantine Conditions
Authors: Hladka Viktoriia 
Published: October 2020

The purpose of the study was to determine the dynamics of motor and functional fitness of 6th grade boys of an underfilled school during the school year under quarantine conditions. Materials and methods. The study involved 6th grade boys (n = 6), who were 11 years old at the beginning of the experiment. The study used methods of mathematical statistics for processing research results, analysis of scientific and methodological literature, testing to assess schoolchildren’s motor and functional fitness. Study results. The indices of the 6th grade students’ motor fitness deteriorated significantly after quarantine. A comparative analysis of the arithmetic mean of the indices showed that in shuttle run 4x9 m (agility) the results deteriorated by 3%, push-ups (strength) by 24.1%, pull-ups (strength) by 41.6%, bent arm hang (strength) by 18.8%, standing long jump (speed and strength qualities) by 1.29%, trunk bend in lying support (flexibility) by 41.5%. As of September 2020, the indices of functional fitness of the 6th grade students also decreased. A comparative analysis of the arithmetic mean of the indices showed that in Shtange test the results deteriorated by 12.6%, and in Genchi test by 14.3%. The introduced quarantine measures and distance learning have negatively affected the schoolchildren’s motor and functional fitness. Conclusions. During the school year, the boys show a positive dynamics of results, and after quarantine measures there is negative dynamics, due to the lack of physical education classes. The testing results indicate the possibility of improving physical education classes, increasing motor activity, enhancing the level of motor fitness, based on the sensitive period of children’s development and individual approach to each school student.
Didactics: Methodological Approaches to Determining the Content of Physical Education Teacher Training
Authors: Ivashchenko Olha , Muszkieta Radosław , Potop Vladimir 
Published: October 2020

The objective of the study was to develop methodological approaches to determining the content of physical education teacher training. Materials and methods. The study involved 62 students of the School of Physical Education, who studied according to the 2001-2005 curriculum. To solve the tasks set, the study used both philosophical and general scientific research methods, including: dialectical method (principle of historicism, principle of systematicity, principle of dialectical contradiction, principle of unity of quality and quantity, principle of dialectical negation, principle of development, principle of causality); systems approach; factor and discriminant analysis. Results. The results of performance analysis show an average level of proficiency in learning material. By the coefficient of variation, the grades in History of Modern World, Culturology, Gymnastics, TMPE, 3rd year vary considerably (>33%). The students’ performance in Therapeutic Physical Training, Fundamentals of Ecology, Thesis has an average level of variability. By most indicators, the students are assessed as a homogeneous group. The analysis of similarities (h2) showed that the most informative indicators of the quality of students’ training are the grades in the following subjects: Teaching Practice (middle school) (0.817); Biomechanics (0.772); Qualification Examination (0.764); Teaching Practice (senior school) (0.763). Conclusions. Factor and discriminant analysis provided objective information on the quality of physical education teacher training. The results of factor analysis do not confirm the objectivity of empirical identification of four groups of academic subjects of the curriculum. The factor structure of the curriculum indicates the need to change the content of education, aimed at improving the training of highly qualified teachers. The training of a physical education teacher should include the following blocks of subjects: professional theoretical and practical training, natural sciences, theory and methods of physical education of schoolchildren, special training in the chosen sport. The results of discriminant analysis show that physical education teacher training is aimed at developing knowledge, abilities and skills in the sections: 1) Means and Methods of Physical Education; 2) Theory and Methods of Motor Abilities Development; 3) Theory and Methods of Teaching Motor Actions.
The value of the shape of the arrangement of the articular surfaces of the clavicle and acromion for the mechanism: both the dislocation of the acromial end of the clavicle and its fracture
Authors: Miziev Ismail A. , Baksanov Hamada D. , Akhkubekov Rustam A. , Bifova Bella R. 
Published: October 2020

Objective. To prove the dependence of a fracture or dislocation of the acromial end of the clavicle on the features of the shape of the arrangement of the articular surfaces of the clavicle and acromion.
Materials and methods. We conducted anatomical studies on 50 unfixed and unopened corpses of people of both sexes and aged 20 to 60 years. Among them, there were 35 men and 15 women. At the same time, we observed three forms of variability in the arrangement of the articular surfaces of the acromion and clavicle.
Results. We studied the radiological forms of the location of the articular surfaces of the clavicle and acromion in 50 patients with a collarbone fracture and in 50 patients with dislocation of the acromial end of the clavicle from 20 to 55 years old, among them 30 were men, 20 women. In all cases, the trauma mechanism was indirect. A certain relationship was revealed between the frequency of a fracture or dislocation and the form of arrangement of the articular surfaces of the acromion and clavicle. Clavicle fracture more often (78.0%) occurred with a vertical arrangement of the articular surfaces of aroma and clavicle.
Conclusion. Anatomical and clinical-radiological studies have shown the dependence of the fracture or dislocation of the acromial end of the clavicle on the peculiarities of the arrangement of the articular surfaces of the clavicle and acromion.