bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cooperative activation of azides by an Al/N-based active Lewis pair – unexpected insertion of nitrogen atoms into C–Si bonds and formation of AlCN3 heterocycles
Authors: Uhl Werner , Martinewski Katja , Bruchhage Julia Silissa , Hepp Alexander , Layh Marcus , Dielmann Fabian , Mehlmann Paul 
Published: October 2019

Abstract
The active Lewis pairs (ALPs) 2,6-Me2H8C5N–C(H) = C(SiMe3)–AlR2 (1a: R =
t
Bu, 1b, R =
i
Bu) have strained AlC2N heterocycles and relatively weak Al–N bonds. They react readily with a series of organic azides R′N3 [R′ = Ph, CH2C6H4(4-
t
Bu),
t
Bu, SiMe3, CH2Ph] by cleavage of the heterocycles and addition of the azides with their α-N atoms to the Al atom. The Al–N interactions result in an activation of the azide groups which insert into the C–Si bonds of the vinyl groups with their terminal γ-N atoms. Compounds with approximately planar five-membered AlCN3 heterocycles and intact N3 groups are formed in highly selective reactions.
Investigating the Influence of Glycerol on the Utilization of Glucose in Yarrowia lipolytica Using RNA-Seq-Based Transcriptomics
Authors: Lubuta Patrice , Workman Mhairi , Kerkhoven Eduard J , Workman Christopher T 
Published: October 2019

Abstract
Glycerol is considered as a promising substrate for biotechnological applications and the non-conventional yeast Yarrowia lipolytica has been used extensively for the valorization of this compound. Contrary to S. cerevisiae, Y. lipolytica seems to prefer glycerol over glucose and it has been reported previously that the presence of glycerol can suppress the consumption of glucose in co-substrate fermentations. Based on these observations, we hypothesized glycerol repression-like effects in Y. lipolytica, which are converse to well described carbon repression mechanisms ensuring the prioritized use of glucose (e.g., in S. cerevisiae). We therefore aimed to investigate this effect on the level of transcription. Strains varying in the degree of glucose suppression were chosen and characterized in high-resolution growth screenings, resulting in the detection of different growth phenotypes under glycerol-glucose mixed conditions. Two strains, IBT and W29, were selected and cultivated in chemostats using glucose, glycerol and glucose/glycerol as carbon sources, followed by an RNA-Seq-based transcriptome analysis. We could show that several transporters were significantly higher expressed in W29, which is potentially related to the observed physiological differences. However, most of the expression variation between the strains were regardless of the carbon source applied, and cross-comparisons revealed that the strain-specific carbon source responses underwent in the opposite direction. A deeper analysis of the substrate specific carbon source response led to the identification of several differentially expressed genes with orthologous functions related to signal transduction and transcriptional regulation. This study provides an initial investigation on potentially novel carbon source regulation mechanisms in yeasts.
The Molecular Basis of Private Property
Authors: Mamounis Kyle J. , Block Walter E. 
Published: October 2019

For political and economic theory in general, libertarianism in particular, property rights are a pillar of central importance. One might describe the schools of political and economic thought solely by their approach to property rights, for example libertarianism as expansive and communism as constrained, with a fair degree of accuracy on the system as a whole.Despite centuries of property rights philosophy, a fundamental weakness persists that can be most easily seen from a natural science perspective. Property classifications, such as between one's physical body, personal property, and other types of so-called private property, underlie much of the property rights theory, yet these classes are more of a result of technological limitations than philosophical or real economic distinctions.We demonstrate through a lens of molecular and developmental biology how distinctions between types of property are misguided or illusory. Using the developing human embryo as the most basic example of property acquisition, we show that all subsequent examples of greater property acquisition and its use are fundamentally the same. The point is further developed with other biological examples.Foundational concepts are of primary importance as their mistake persists through even the most elegant deductions. In order to defend itself from the political and economic attacks, the property rights ethic must be consistent and logical. For this, any artificial or contradictory concepts must be shed.
INTERLOCKING SYSTEM PADA KONSTRUKSI KNOCK DOWN BANGUNAN TRADISIONAL JAWA TAJUG SEBAGAI TEKNOLOGI RESPONSIF GEMPA
Authors: Dewi Nitih Indra Komala , Pratiwi Sri Novianthi , Fajria Mei Nisa 
Published: October 2019

Abstract: Java Island is located on the ring of fire having active earth plate movements. The movement of the earth plates causes earthquakes with very high intensity. Earthquake factor is a major consideration in the construction of building structure systems. Traditional Javanese buildings have earthquake responsive building structures. The use of knock down timber construction connections is classified as an interlocking system in the form of notch, fulcrum, compressive force, hook and attraction. The system causes flexibility, attenuation, stability, elasticity in the framework of the building resulting in a unity in building systems that are responsive to the earthquakes. This study describes the interlocking system technology found in knock-down timber construction in traditional Java Tajug buildings. Keywords: Knock Down, Interlocking System, Timber Connection System, Traditional Java Tajug Buildings Abstrak: Pulau Jawa terletak pada jalur ring of fire memiliki pergerakan lempeng aktif. Pergerakan lempeng ini menyebabkan terjadinya gempa dengan intensitas yang sangat tinggi. Faktor gempa menjadi pertimbangan utama dalam pembentukan sistem struktur pada bangunan. Bangunan tradisional Jawa memiliki sistem struktur bangunan yang responsif gempa. Penggunaan sambungan konstruksi kayu knock down diklasifikasikan sebagai sistem koncian atau pengunci (interlocking system) yang berupa takik, tumpu, tekan, kait dan tarik. Sistem tersebut mengakibatkan sifat fleksibilitas, redaman, stabilitas, elastisitas pada rangka bangunan sehingga menjadi satu kesatuan dalam sistem bangunan yang responsif terhadap gempa. Kajian ini mendeskripsikan tentang teknologi sistem pengunci (interlocking system) yang terdapat dalam konstruksi kayu dengan sistem knock down pada bangunan tradisional Jawa tajug. Kata Kunci: Knock Down, Interlocking System, Sistem Sambungan Kayu, Rumah Tradisional Jawa Tajug.
PENERAPAN KONSEP INTEGRASI ANTAR TUANG PUBLIK PADA REDESAIN STASIUN KERETA API PATI
Authors: Aziz Ardi , Ratriningsih Desrina 
Published: October 2019

Abstract: Pati Train station is one of the second class stations in Pati Regency. Its presence is very helpful in transportation activities between regions within provinces and between provinces. Train station has an important role in relation to mobility of society. But in reality, train stations often lack adequate facilities such as the lack of large waiting rooms, of seats for resting passengers, and of other supporting facilities. Pati Train Station is redesigned on the basis of activation planning for Semarang-Lasem Railway by the Indonesian Railways (PT KAI). In the future, the station's redesign improves the old station by exploring the facts and issues occuring in the field so that the two factors are used as the basis for the design. The concept of “public spaces integration” used in station redesign aims to make it easier for users to get connected to public spaces inside and outside Pati train station. The method used is descriptive method, carried out by collecting primary and secondary data relating to the design object and then analyzing data based on public space theory which is then used as a design solution in the concept of public spaces integration.Keywords: station; train; Pati; integration; public space Abstrak: Stasiun kereta api Pati adalah satu dari beberapa stasiun kelas dua yang berada di Kabupaten Pati. Keberadaan stasiun ini sangat membantu dalam kegiatan transportasi antar daerah baik di dalam propinsi maupun antar propinsi. Stasiun kereta api memiliki peranan penting yang berkaitan dengan mobilitas masyarakat. Namun, dalam kenyataannya, fasilitas yang terdapat di stasiun kurang memadai dan belum memenuhi standar. Stasiun kereta api Pati di redesain dengan dasar perencanaan aktivasi jalur kereta api Semarang-Lasem oleh Perkeretaapian Indonesia (PT KAI). Pada nantinya redesain stasiun ini memperbaiki stasiun yang lama dengan menggali fakta dan issu yang terjadi di lapangan sehingga menjadikan kedua faktor tersebut sebagai dasar pemikiran perancangan. Konsep “Integrasi Antar Ruang publik” yang digunakan pada redesain stasiun ini bertujuan untuk memudahkan pengguna agar terhubung/terkoneksi ke ruang publik yang ada di dalam stasiun dan luar stasiun kereta api Pati. Metode yang digunakan yaitu metode deskriptif, dilaksanakan dengan mengumpulkan data-data primer dan sekunder yang berkaitan dengan objek perancangan kemudian melakukan analisa data berdasar teori ruang public yang kemudian digunakan sebagai solusi perancangan dalam konsep integrasi antar ruang publik.Kata kunci: stasiun; kereta api; Pati; integrasi; ruang publik
PENERAPAN KONSEP HEALING ARCHITECTURE PADA RUMAH SAKIT TIPE D DI KABUPATEN KENDAL
Authors: Azza Shafira , Natalia Dita Ayu Rani 
Published: October 2019

Abstract: Kendal Regency is a region in Central Java Province that has a large area with increasing number of resident. Increasing number of residents set off increasing number of disease but health facility in Kendal Regency is not available yet. Thus, health facility or hospital is needed in order to help healing process for the residents. Type D hospital is designed using the application of healing architecture concept because this concept will be really helpful for the patients in their healing process. Healing Architecture is implemented in the building of Type D Aisyiyah Hospital with outdoor and indoor design thus creating an atmosphere that can influence the psychology and physic of the patients in healing process. The data was obtained through primary and secondary data collection. The primary data was done through interview, observation, location mapping, and documentation. Secondary data was collected from related agencies and literature study from journal or related paper. The result from the application of healing architecture concept on Type D Aisyiyah Hospital in Kendal Regency was showed off on the building façade, outdoor room, and indoor room of the hospital which is helpful in healing process by considering structure of building and utility for hospital needs.Keywords: Healing Architecture, Hospital, Kendal Regency Abstrak: Kabupaten Kendal adalah salah satu kabupaten yang berada di Jawa Tengah yang memiliki wilayah yang cukup luas dengan perkembangan penduduk yang kian meningkat. Bertambahnya pertumbuhan penduduk menyebabkan semakin banyak pula penyakit yang berkembang tiap tahunnya, namun fasilitas kesehatan di Kabupaten Kendal masih kurang ketersediaannya sehingga diperlukan fasilitas kesehatan berupa rumah sakit untuk membantu penyembuhan masyarakat. Rumah sakit dengan tipe D dirancang menggunakan penerapan konsep healing architecture karena konsep ini sangat membantu pengguna terutama pasien dalam proses penyembuhan. Healing Architecture merupakan konsep penyembuhan yang dilakukan demi menciptakan bentuk dan lingkungan arsitektur yang memiliki aspek people, process and place. Healing Architecture diimplementasikan dalam bangunan Rumah Sakit tipe D di Kabupaten Kendal dengan desain ruang luar dan dalam sehingga menciptakan suasana yang dapat berpengaruh terhadap psikologi dan fisik terapi pasien dalam proses penyembuhan. Metode pengumpulan data menggunakan metode pengumpulan data primer yaitu berupa wawancara, pengamatan, pemetaan lokasi serta dokumentasi, dan metode pengumpulan data sekunder yaitu berupa data dari instansi yang terkait serta studi literatur terhadap jurnal atau karya ilmiah yang berkaitan. Hasil penerapan konsep healing architecture pada rumah sakit tipe D di Kabupaten Kendal diterapkan pada fasad bangunan, ruang luar dan ruang dalam pada rumah sakit yang dapat membantu proses penyembuhan pasien dengan mempertimbangkan struktur pada bangunan dan utilitas untuk kebutuhan rumah sakit.Kata Kunci: Healing Architecture, Rumah Sakit, Kabupaten Kendal
KAJIAN BENTUK, FASAD, DAN RUANG DALAM PADA MASJID CHENG HO PALEMBANG
Authors: Narhadi JM Sri 
Published: October 2019

Abstract: The architecture of places of worship is one of architecture that is specifically designed to meet human needs in terms of worship. Architecture for a place of worship itself, consisting of church architecture, temples, temples, and mosques. The mosque is a place of worship that is always there in every city in Indonesia, because the majority of Indonesian people are Muslims. Over time, the architecture of the mosque also developed in terms of design by adjusting the culture and environmental conditions. The Cheng Ho Mosque in Palembang is one of the mosques that was established in the city of Palembang with the mosque's unique architectural design and style. The full name of the mosque itself is Al Islam Muhammad Cheng Ho Sriwijaya Mosque. As one of the tourist attractions and also a place of worship of Muslims, Cheng Ho Mosque has attracted the attention of writers to conduct research on mosque design. The different design makes the writer want to research more about the shape, facade and inner space of the Ceng Ho Mosque. Therefore, this research was made under the title Study of Forms, Facades, and Inner Space at the Ceng Ho Mosque in Palembang.Keywords: Form, Façade, Inner Space Abstrak: Arsitektur tempat ibadah merupakan salah satu arsitektur yang didesain khusus untuk memenuhi kebutuhan manusia dalam hal beribadah. Arsitektur untuk sebuah tempat ibadah sendiri, terdiri dari arsitektur gereja, vihara, klenteng, dan juga masjid. Masjid merupakan salah satu tempat ibadah yang selalu ada di setiap kota di Indonesia, karena mayoritas umat Indonesia adalah muslim. Seiring berjalannya waktu, arsitektur masjid pun berkembang dari segi desain dengan menyesuaikan kebudayaan dan kondisi lingkungan sekitar. Masjid Cheng Ho Palembang merupakan salah satu masjid yang didirikan di Kota Palembang dengan desain dan gaya arsitektur masjid yang cukup unik. Nama lengkap dari masjid ini sendiri adalah Masjid Al Islam Muhammad Cheng Ho Sriwijaya. Sebagai salah satu tempat wisata dan juga tempat ibadah umat muslim, Masjid Cheng Ho telah menarik perhatian penulis untuk melakukan penelitian terhadap desain masjid.. Desain yang berbeda membuat penulis ingin menelliti lebih lanjut mengenai bentuk, fasad dan ruang dalam dari Masjid Ceng Ho. Oleh karena itu, penelitian ini dibuat dengan judul Kajian Bentuk, Fasad, dan Ruang Dalam pada Masjid Ceng Ho Palembang. Kata Kunci: maksimal; empat; kata; kunci.
IDENTITAS KAWASAN KAMPUNG PARALON DI PERMUKIMAN PADAT MELALUI KONSEP ECOVILLAGE Studi Kasus: Kampung Paralon Desa Bojongsoang Kabupaten Bandung
Authors: Wijaya Karto , Wibowo Heru , Permana Asep Yudi 
Published: October 2019

Abstract: Architecture as one of the fields that cannot be separated from how to process space is very appropriate in supporting the Eco Village program because the conception of space in the field of architecture has a three-dimensional conception. Through understanding the concept of three-dimensional space with limited land owned by each citizen does not mean that the community cannot cultivate their land into productive land, namely making agricultural land (agriculture). This makes observers interested in researching villages that have long been built, but are now blocked by housing that was once an empty space (in this case rice fields) in Bojongsoang Village, Bojongsoang District, Bandung Regency as a form of observer participation in developing an urban farming approach to achieving sustainability (sustainable). The purpose of this study was to find out which Eco Village models exist in the region Paralon Village as an Eco-Architecture concept in supporting the development of Sustainable City, as one of the eco-architecture models in urban villages by utilizing the land and space of each community member. Keywords: Eco Village; Sustainable City; Settelment Abstrak: Arsitektur sebagai salah satu bidang yang tidak dapat dipisahkan dari cara mengolah ruang sangat tepat dalam mendukung program Eco Village karena konsepsi ruang dalam bidang arsitektur memiliki konsepsi tiga dimensi. Melalui pemahaman konsep ruang tiga dimensi dengan lahan terbatas yang dimiliki oleh setiap warga negara tidak berarti bahwa masyarakat tidak dapat mengolah lahan mereka menjadi lahan produktif, yaitu membuat lahan pertanian (pertanian).Hal ini membuat para pengamat tertarik meneliti desa-desa yang telah lama dibangun, tetapi sekarang dihambat oleh perumahan yang dulunya merupakan ruang kosong (dalam hal ini sawah) di Desa Bojongsoang, Kabupaten Bojongsoang, Kabupaten Bandung sebagai bentuk partisipasi pengamat dalam mengembangkan suatu pendekatan urban farming untuk mencapai keberlanjutan (sustainable).Tujuan dari penelitian ini adalah untuk mengetahui model Eco Village yang ada di wilayah Desa Paralon sebagai konsep Eco-Architecture dalam mendukung pengembangan Kota Berkelanjutan, sebagai salah satu model eco-architecture di desa-desa perkotaan dengan memanfaatkan lahan dan ruang dari setiap anggota komunitas.Kata kunci: Desa Ramah Lingkungan; Kota Berkelanjutan; Permukiman
Yüksek gerilim hattına yakın evlerde elektromanyetik alan düzeyleri ve semptom varlığı
Authors: YAVUZ Cavit , ARSLANYILMAZ M. Müsenna , VAİZOĞLU Songül A. , KESKİN Can , ÖNGÖRE Ramazan , GÜLER Çağatay 
Published: October 2019

Amaç: Bu çalışmanın amacı yüksek gerilim hattı yakınında bulunan evlerde elektromanyetik alan düzeylerinin ve bu evlerde yaşayanlarda bazı semptomların varlığının belirlenmesidir. Gereç ve Yöntem: Bu amaçla bu tanımlayıcı çalışmada Ankara’da, yakınında yüksek gerilim hattı bulunan 74 evde ve evin bulunduğu binanın çevresinde elektromanyetik alan ölçümü yapılmış ve bu evlerde yaşayan 18 yaş üstü 141 kişiye sağlık durumlarının ve semptomların değerlendirildiği bir anket uygulanmıştır. Bulgular: Evlerde elektromanyetik alan ortalaması 2,18 ±1,25 mG olarak saptanmıştır, %41,9’u 1-3. kattadır. Evlerin balkonları elektromanyetik alan ortalamalarının en fazla olduğu alanlar olmuştur. Katılımcıların %50,4’ü erkek, %%66,4’ü 50 yaş üstündeydi. Evlerdeki elektromanyetik alan düzeyi ile yüksek gerilim hattına uzaklık arasında istatistiksel olarak anlamlı ve negatif bir korelasyon belirlenmiştir. Sorgulanan semptom sıklığı ve toplam semptom sayısı ile evde ölçülen elektromanyetik alan düzeyleri arsında anlamlı farklılık bulunamadı. Sonuç: Elektromanyetik alanlar sağlıkla ilgili çeşitli endişelere neden olmaktadır. Bu alanda sağlık etkileri ile ilgili çalışmalar artırılmalıdır. Bu tanımlayıcı çalışmanın sonuçları farklı değerlendirme yaklaşımlarının ortaya konulmasının yararlı olacağını göstermektedir.
Klinik laboratuvarda kalite yönetimi: altı sigma prosedürünün uygulanması
Authors: DAĞLIOĞLU Gülçin , GÖRÜROĞLU ÖZTÜRK Özlem , İNAL Tamer 
Published: October 2019

Amaç: Bu çalışmada kalite yönetim aracı olan altı sigma protokolü kullanılarak klinik laboartuvar süreçlerindeki iyileştirici etki düzeylerinin belirlenip sağladığı pozitif katkıların ortaya konulması amaçlanmıştır.Gereç ve Yöntem: Bu çalışmada; Çukurova Üniversitesi Tıp Fakültesi Balcalı Sağlık Uygulama ve Araştırma Merkezi-Merkezi Laboratuvarı’nda oluşan hataların sınıflandırılması, nedenlerinin araştırılması ve yöntem performanslarının değerlendirilmesi için “Altı Sigma Protokolü” uygulanmıştır. Evrensel standartlarda çalışabilmek için hataların kaynağı ve sıklığının analizi yapılarak öncelikle mevcut durum tespit edilmiştir. Oluşan hataların saptanması ve sınıflandırılması sonucunda, en çok etkilenen süreçlerden başlanarak, düzeltici faaliyetler planlanmıştır. Bulgular: Preanalitik evre hata sayısı sigma düzeylerinin 4,250-4,357’den 4,500-4,625’e yükseldiği bulunmuştur. Analitik evrede en yüksek sigma düzeyinin amilaz testi için 10,5 olduğu görülmüştür. Postanalitik evrede ise; potasyum test istek sonuç süresi sigma düzeyinin süreç sonunda 2,250’den 2,500’e yükseldiği belirlenmiştir. Sonuç: Bu çalışma; hasta sağlığına olumsuz yansıyabilecek hataların giderilmesine, hasta memnuniyetine, uygun internal kalite kontrol kurallarının seçilmesine olanak sağlamıştır. Düzeltici faaliyetler ve alınan önlemler doğrultusunda kaliteli hizmetin bir maliyeti olmasına karşın kalitesizlik maliyetleri azaltılmıştır. Laboratuvar performansının evrensel ölçütlerde hesaplanarak, dünyadaki diğer klinik laboratuvarlar ile performans karşılaştırması da 4-5 üzerinde olması evrensel kalite standartlarında hizmet verdiğimizi teyit etmiştir.
Hemşirelikte teori ve model kullanımı: Nitel bir çalışma
Authors: GÖÇMEN BAYKARA Zehra , ÇALIŞKAN Nurcan , ÖZTÜRK Deniz , KARADAĞ Ayişe 
Published: October 2019

Amaç: Hemşirelik teori ve modelleri, disipline özgü araştırmalara, eğitime ve bakım uygulamalarına yön vererek profesyonelleşmeye katkıda bulunmaktadır. Dolayısıyla meslek mensuplarının teori ve model kullanımı hakkındaki düşüncelerinin belirlenmesi oldukça önemlidir. Bu araştırma, hemşirelerin hemşirelik teori ve modellerine yönelik düşüncelerini belirlemek amacıyla gerçekleştirilmiştir. Gereç ve Yöntem: Nitel bir çalışma olarak yapılan araştırma, toplam 36 hemşire (yüksek lisans öğrencisi n:12, doktora öğrencisi n:12, hemşire n:12) ile yapılmıştır. Araştırma verileri, Yarı Yapılandırılmış Görüşme Formu acılığıyla odak grup görüşmesi ile elde edilmiştir. Görüşmeler ses kayıt cihazına kaydedilmiştir. Görüşmeden elde edilen veriler tematik olarak analiz edilmiştir. Bulgular: Bu araştırmada üç ana tema belirlenmiştir. Bunlar; hemşirelik teori ve modelleri ile çalışmanın olumlu ve olumsuz yönleri, teori/model ile çalışmaya engel oluşturan faktörler ve model kullanımını artırmaya yönelik önerilerdir. Bu ana temalar uygulama, araştırma, yönetim ve eğitim alanlarını kapsayacak şekilde yapılandırılmıştır. Sonuç: Hemşireler, hemşirelik teori/modelleri konusunda yetkinliğe sahip hemşire sayısının arttırılmasını, bakım gereksinimleri temel alınarak uygun teori ve modellerin geliştirilmesini, lisans programında bu konulara yer verilmesini, kültüre özgü ve bakıma yansıyacak teori ve modellerin geliştirilmesini önermişlerdir.