bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengelolaan Limbah Cair Industri Batik menggunakan Mikroorganisme di Kecamatan Cluring Kabupaten Banyuwangi
Authors: Jannah Iis Ni'matul , Muhimmatin Ifa 
Published: November 2019

UNESCO telah menetapkan batik Indonesia sebagai warisan budaya. Kasus ini membuat meningkatnya permintaan batik. Meningkatnya permintaan batik adalah peluang bisnis bagi sebagian orang. Dengan demikian, banyak industri kecil batik dan industri menengah batik (IKM) mulai bermunculan yang berdampak positif dan negatif. Dampak positifnya adalah meningkatnya ekonomi masyarakat dan membuka lapangan kerja baru. sedangkan dampak negatifnya adalah masih belum banyak pengrajin batik yang memiliki pengetahuan tentang cara mengolah limbah cair batik. Limbah cair yang dihasilkan oleh industri batik di Kabupaten Cluring dalam bentuk sisa pewarna yang disimpan dalam reservoir dan dibiarkan meresap ke dalam tanah tanpa diproses terlebih dahulu. kasus ini sangat berbahaya jika pewarna yang tersisa merembes dan masuk ke sumber air tanah karena pewarna yang tersisa mengandung senyawa berbahaya. Hasil analisis situasi memperoleh masalah mitra, yaitu mitra kurang memiliki pengetahuan dan keterampilan tentang cara mengelola atau mengolah limbah cair batik yang dihasilkan oleh industri batik. Oleh karena itu, solusi yang ditawarkan kepada mitra adalah dalam bentuk edukasi tentang bagaimana mengelola limbah cair batik dengan menggunakan metode lumpur aktif dengan memanfaatkan mikroorganisme. Sasaran dari kegiatan ini adalah untuk meningkatkan pengetahuan dan keterampilan para mitra tentang cara mengolah limbah cair batik. Metode lumpur aerob aktif digunakan untuk mengolah limbah cair batik karena dapat mendegradasi limbah secara efisien. Metode ini dilakukan dengan menyiapkan pembenihan, melakukan aklimatisasi, dan mengolah limbah cair batik dengan mikroorganisme yang telah dibuat. Berdasarkan hasil kegiatan layanan yang dilakukan oleh Najiha Batik sebagai mitra, Najiha Batik telah menerima pendidikan seperti pengetahuan dan keterampilan tentang cara mengolah limbah cair batik dengan memanfaatkan mikroorganisme (mengaktifkan metode lumpur) yang dilakukan secara aerobik. Metode lumpur aktif dipilih karena mempertimbangkan beberapa hal termasuk bahan yang digunakan untuk membuat lumpur aktif dalam bentuk lumpur sungai dan lumpur dari selokan yang mudah diperoleh dari pembuangan limbah. Jadi, metode ini tidak hanya ekonomis tetapi juga membutuhkan daya listrik terus menerus karena digunakan untuk aerasi selama sistem lumpur aktif berjalan secara aerobik.
Kata Kunci: Pegelolaan Limbah Cair, Batik, Mikroorganisme
Depicting the Landscape of Adipose Tissue-Specific Macrophages and Their Immunometabolic Signatures during Obesity
Authors: Korf Hannelie , Boesch Markus , Feio-Azevedo Rita , Smets Lena , Vandecasteele Roselien , van der Merwe Schalk 
Published: November 2019

Abstract
Obesity is a widespread health condition, which can lead to the development of metabolic disorders, such as type 2 diabetes mellitus, nonalcoholic fatty liver disease and cardiovascular diseases. Obesity is marked by the excessive deposition of fat in adipose tissue sites combined with chronic low-grade inflammation. Within this clinical setting, it is well established that adipose tissue macrophages exhibit prominent roles in regulating inflammation and metabolism. However, aside from these well-established roles, the involvement of microenvironmental cues as well as underlying cellular metabolism in driving immunological fate decisions within macrophages are poorly understood. Here we aim to map the different adipose tissue-derived macrophage subsets, together with their metabolic and functional profiles. Finally, we discuss their potential contribution during homeostasis and disease progression associated with obesity.
Pemberian Pupuk Alam Terhadap Serapan Nitrogen dan Hasil Sawi di Alfisols
Authors: Sumarno Sumarno , Widjianto Hery , Kusuma W Rosinta 
Published: November 2019

<p>This research conducted to determine the exact formula and dosage to increase the uptake of N and increase yield of green mustard. The research conducted at Jumantono dryland research center, Karanganyar and Laboratory of Chemistry and Soil Fertility, Faculty of Agriculture UNS Solo. This study uses a randomized complete block design (RCBD) using 5 formulas as the first treatment factor and 4 dosages as second treatment factor. The data analysis used F test level of 5% and if significant continued by DMRT (Duncan Multiple Range Test) level of 5%. The variables of this research were weight of wet stover, weight of dry stover, N total and absorption of N. The results showed that the combination of dosage and formula of natural fertilizers can increase N uptake and yield of mustard on the ground Alfisols.</p>
Respon Pemberian Ethyl Methane Sulfonate Terhadap Kualitas Salak Pondoh
Authors: Nandariyah Nandariyah , Sukaya Sukaya , Liesdiana Via 
Published: November 2019

<p>This research was conducted in Tapansari snakefruit plantation, Pakem, Sleman, Yogyakarta. This study use Completely Randomized Design with one factor. Factor used is the EMS concentration (K) difference that consists of 5 levels concentration of 0%, 0.5%, 1%, 1.5%, and 2%. The treatment is given to the female flowers from the tip to the base as much as 5 ml in each before pollination. The data were analyzed using descriptive analysis and analysis of variance by the F test level of 5% and continued by DMRT level of 5%. The result showed that application of EMS in the female flowers before pollination can reduce the size of some snakefruit sample in 1%, 1.5%, and 2% concentrations; however, it did not show significant effect on the seed size reduction. The application of EMS does not able to produce seedless snakefruits. </p>
Toksisitas Biji Srikaya Terhadap Kumbang Tepung (Tribolium Castaneum) Pada Gandum
Authors: Subagiya Subagiya , Sulistyo Ato , Nurchasanah Umi 
Published: November 2019

<p>Wheat <em>(Triticum aestivum)</em> is one of main food source with carbohydrates which is consumed by world people. The loss of wheat during storage is caused by pests attack. Flour beetle <em>(Tribolium castaneum)</em> is one of the main pests of wheat flour. Biological insectisidies is a solution to solve the attack of warehouse pests. The aim of research are to study the effectiveness of srikaya seeds on <em>T. castaneum</em> in wheat flour and to study the quality of wheat flour after the application srikaya seeds to <em>T. castaneum. </em>The research were be held in Pandan Rejo Village, Kebakkramat Sub-District, Karanganyar Regency on 105 asl altitude during September until October 2017. The research use Complete Randomized Design (CRD) with two factors of four repetitions. Dose treatment for Srikaya seeds consist of four levels of controls, 2.5 g/100 g wheat, 5 g/100 g wheat, and 10 g/100 g of wheat and the form of application consist of two kinds are 0.5 mm srikaya seed and 1 mm srikaya seed. Research variables which are observed were toxicity srikaya seed, imago mortality, moisture content, wheight shrinkage of wheat, color of wheat, and odor of wheat. The result show that LD50 of srikaya seed on a form 0.5 mm is 3.97 g/100 g wheat and form 1 mm is 4.70 g/100 g wheat. The application of the srikaya seed to minimize changes in quality wheat. The lowest shrinkage weight is 2.43 g and highest on the control of wheat color 5.805 g. control treatment from while to white murky scales (2). Scent control treatment of wheat does not become musty semlling scented (1).</p>
Locked Traumatic Pisiform Dislocation
Authors: Saglam Fevzi , Dagtas Mirza Zafer , Sağlam Sonmez , Baysal Ozgur 
Published: November 2019

Case:
A 32-year-old man presented to the emergency department with several carpal bone fractures and a locked distal pisiform dislocation after trauma. Treatment consisted of open surgical and reduction, osteosynthesis with a single Kirschner wire, and ligament repair. The patient's functional outcome was excellent, and his Mayo wrist score was 90 at 36 months after injury.

Conclusions:
Pisiform dislocations may be difficult to diagnose because anteroposterior and lateral radiographs may not be sufficient to visualize the injury. A 30° semisupinated wrist x-ray and computed tomography can be helpful. A satisfactory clinical result may be achieved if distal pisiform dislocations are detected early and managed surgically with open reduction and ligament repair.
Effect of Student Teams Achievement Division and Think-Pair-Share on Students' Achievement in Reading Comprehension
Authors: Ugwu Eucharia Okwudilichukwu 
Published: November 2019

AbstractThe study investigated the effect of two cooperative learning strategies, Student Teams-Achievement Divisions (STAD) and Think-Pair-Share (TPS) on senior secondary school students’ achievement in reading comprehension in Vandeikya Local Government Area, Benue State, Nigeria. A total of 78 students (43 males and 35 females), drawn from three secondary schools participated in the study. Experimental and control conditions were randomly assigned to the three intact classes: EG1 (STAD), EG2 (TPS) and CG (Control Group). The instrument used was Reading Comprehension Achievement Test (r=0.784). Data were analyzed using Mean, Standard Deviation and Analysis of Covariance (ANCOVA). The results show higher achievement gains for students in the EG1 and EG2 over those of the CG, but not across gender. The findings support the existing evidence on the efficacy of cooperative learning over the traditional teaching method. English language teachers will therefore find the two techniques useful in teaching reading comprehension.

Keywords: cooperative learning, Student Teams-Achievement Divisions, Think-Pair-Share, academic achievement, reading comprehension
Childhood maltreatment as a risk factor for cancer: Findings from a population-based survey of Canadian adults
Authors: Hovdestad Wendy , Shields Margot , Shaw Amanda , Tonmyr Lil 
Published: November 2019

Abstract
Background: Childhood maltreatment (CM) is an established risk factor for various mental and substance use disorders. This study adds to existing evidence that CM may also be a risk factor for cancer. Methods: Based on data from a sample of 9,783 men and 12,132 women from the 2012 Canadian Community Health Survey - Mental Health (CCHS - MH), this analysis explores mediated associations between cancer in adulthood and different levels of exposure to three types of CM—childhood physical abuse (CPA), childhood sexual abuse (CSA), and childhood exposure to intimate partner violence (CEIPV). “Cancer” was defined as an affirmative response to either of these questions: ‘‘Do you have cancer?’’ or ‘‘Have you ever been diagnosed with cancer?’’ The potential mediators were: smoking, depression, alcohol abuse/dependence, life stress, obesity, and physical activity. Results: For women, but not men, having experienced CM was significantly associated with a cancer diagnosis in adulthood, even when effects due to age and socio-demographic characteristics were controlled. Smoking, life stress, depression, and alcohol abuse/dependence reduced the strength of the association between CM and cancer in women. However, most associations remained statistically significant when controlling for effects due to these behavioural and other mediators. Evidence indicated a “dose-response” relationship, in that the likelihood of reporting cancer increased with the number of abuse types (CPA, CSA, CEIPV) reported, and with the severity of CPA. Conclusions: The analyses suggest an association between CM and cancer in women, even when the effects of known risk factors were taken into account. The association was graded, becoming stronger as CM exposure increased. Implications for the provision of cancer screening and other health care services to women with histories of CM to reduce health disparities are discussed.
Group Post-Admission Cognitive Therapy for Suicidality vs Individual Supportive Therapy for the prevention of repeat suicide attempts: a randomized controlled trial.
Authors: Chaïb Laurent Stephane , Lopez-Castroman Jorge , Abbar Mocrane 
Published: November 2019

Abstract
Introduction: Suicide is a serious public health problem. The development and use of effective treatments for people hospitalized for suicide attempts remain a priority. Regarding psychosocial treatment, the evidence for treatments that effectively prevent suicide repetition of suicide attempts is extremely thin. There is some evidence that cognitive behavioural therapy may be effective for reducing suicide behaviour. The primary aim of this study is to compare Group Post-Admission Cognitive Therapy for Suicidality (GPACTS) versus Individual Supportive Therapy (IST) for preventing suicide. Methods and analysis: 240 participants with a high suicide risk score according to a Mini international Neuropsychiatric Interview will be randomly to either GPACTS or IST. This is a multicentre, parallel group, randomized (1:1 ratio), two-tailed-superiority trial with endpoint-assessor blinding. Patients meeting inclusion criteria during a screening visit will be enrolled in the study and randomized into two groups: one group will undergo six weeks of GPACTS, and the second group will undergo six weeks of IST. Following six weeks of interventional therapy, patients are followed-up for 12 months. Follow-up for both groups is identical and includes the administration of questionnaires at baseline and then within 10 days after the end of therapy sessions and then at 3, 6 and 12 months following the end of GPACTS/IST sessions. Discussion: To our knowledge, this is the first RCT of its kind to be conducted in France and so far, there are no studies in the literature on group psychotherapy for the treatment of individuals who have attempted suicide. The outcomes will provide clear guidance for professionals to apply psychological intervention with suicide attempts. The protocol respect ethical principles and ethical approval were obtained from the local ethics committee. The results will be disseminated through an original research published as original research in peer-reviewed manuscript, through a therapist manual for cognitive therapy, and presentations at research conferences.
Association between maternal sleep duration and quality and the risk of preterm birth: a systematic review and meta-analysis of observational studies
Authors: wang ling , Jin Feng 
Published: November 2019

Abstract
Study Objectives: The association between sleep duration and quality and the risk of preterm birth remains controversial.Methods: Relevant studies were retrieved from the PubMed and Web of Science databases up to the end of September 2018 and the reference lists of the retrieved articles were reviewed. Random effects models were applied to estimate summarized relative risks (RRs) and 95% confidence intervals (CIs).Results: Ten identified studies (nine cohort studies and one case-controlled study) examined the associations between sleep duration and quality and the risk of preterm birth. Compared with women with the longest sleep duration, the summary RR was 1.23 (95% CI = 1.01-1.50) for women with the shortest sleep duration, with moderate between-study heterogeneity (I2 = 57.4%). Additionally, as compared with women with good sleep quality, the summary RR was 1.54 (95% CI = 1.18-2.01) for women with poor sleep quality (Pittsburgh Sleep Quality Index > 5), with high between-study heterogeneity (I2 = 76.7%). The results of stratified analysis by trimester, geographical location, study design, type of preterm birth, and adjustment for potential confounders were comparable to those of the main meta-analysis. Funnel plots as well as the Egger’s and Begg’s tests showed no evidence of publication bias.
Conclusions: This systematic review and meta-analysis revealed that short sleep duration and poor sleep quality may be associated with an increased risk of preterm birth.
Comparison of Cytokine Levels in the Aqueous Humor of Polypoidal Choroidal Vasculopathy and Neovascular Age-Related Macular Degeneration Patients
Authors: Zhou Huiying , Zhao Yinyu , Yuan Mingzhen , Chen Youxin 
Published: November 2019

Abstract
Background The concentrations of cytokines in the aqueous humor from neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV) may vary. The study was conducted to compare various cytokine levels in the aqueous humor of eyes with PCV, nAMD and control. Methods The present case control study included 49 treatment-naïve eyes from 49 patients (PCV 24, nAMD 11, and cataract 14 eyes). Totally 34 angiogenic and inflammatory cytokines in the aqueous humor were measured by Luminex bead-based multiplex array. Results After adjusting for gender and age by multivariate logistic analysis, concentrations of IL-31, LIF, SDF1-α, VEGF-A, VEGF-D were significantly higher in eyes with nAMD or PCV compared with control eyes (all P<0.05, times in nAMD: 59.5, 6.0, 7.0, 4.5, 5.6, respectively, times in PCV: 51.9, 5.21, 6.6, 4.0, 5.1, respectively ), and concentrations of HGF, IP-10, MCP-1, IL-13 were significantly lower in eyes with nAMD or PCV than in control eyes (all P<0.05, times in nAMD: 2.6, 2.0, 4.5, 4.7, respectively, times in PCV: 1.9, 3.0, 3.0, 2.8, respectively), but none of the 34 cytokines, including VEGF and IL-8, showed significantly different between eyes with nAMD and PCV. Conclusions Various cytokines involved in inflammation and angiogenesis including elevated IL-31, LIF, SDF1-α, VEGF-A, VEGF-D might be involved in the pathogenesis of nAMD or PCV. None of the 34 cytokines may help to differentiate nAMD and PCV.
Analysis of partnerships for actions intra-sectoral and inter-sectors for health in areas of high socio-environmental vulnerability in the city of São Paulo/Brazil: a mixed method study
Authors: Bezerra Patricia Melo , Guerriero Iara Coelho Zito 
Published: November 2019

Abstract
Context: Since poverty areas are socioeconomic complex and limiting environments, there is a need to develop intra-sectoral and inter-sectoral actions in the health territory in order to achieve the economic and social well-being of people and society. This research aims to understand the relationship between inter-sectorial and inter-sectoral actions for health and socio-environmental groupings of the most vulnerable health territories in the city of São Paulo, identify which are the most frequent partners of these actions and how professionals experience these partnerships in their daily lives.
Method: We adopted the mixed sequential and explanatory method. In the first phase, an online form was applied and identifies the Basic Health Units (BHU) that take place as intersectoral actions with more partners. In the second phase, we explored how the professionals consider the characteristics of the territory where they act to seek partnerships and how they carry out the actions.
Results: Analysis of quantitative data indicated that: a) More than 98% of BHUs conduct intra- and inter-sectoral partnerships and b) there is no relationship between the indices of the most vulnerable groupings and the presence of intra- and inter-sectoral actions with statistical significance p <0.05. The content analysis of literal transcriptions pointed out that: intra- and inter-sectoral practices developed in the health territories were driven by the needs of the treatment of diseases or by the precarious conditions of life of individual or collectivities. However, in order to assist different types of violence, health professionals avoid seeking partnerships, including with the Tutelary Council and the Center for Human Rights, as they fear they will suffer reprisals by those who cause this violence. There was consistency between quantitative and qualitative data, except for partnership with education, other BHUs, environment, and the Tutelary Council.
Conclusion: The construction of personalized partnerships for individual and collective health, in order to cope with social inequalities; of chronic diseases and by phases of the life cycle involved in socioeconomic fragilities that generate more poverty is part of the job from BHU’s professionals.
Functional and population genetic features of copy number variations in two dairy cattle populations
Authors: Lee Young-Lim , Bosse Mirte , Mullaart Erik , Groenen Martien A. M. , Veerkamp Roel F. , Bouwman Aniek C. 
Published: November 2019

Abstract
Background Copy Number Variations (CNVs) are gain or loss of DNA segments that are known to play a role in shaping a wide range of phenotypes. In this study, we used two dairy cattle populations, Holstein Friesian and Jersey, to discover CNVs using the Illumina BovineHD Genotyping BeadChip aligned to the ARS-UCD1.2 assembly. The discovered CNVs were investigated for their functional impact and their population genetics features. Results We discovered 14,272 autosomal CNVs, which were aggregated into 1,755 CNV regions (CNVR) from 451 animals. These CNVRs together cover 2.8% of the bovine autosomes. The assessment of the functional impact of CNVRs showed that rare CNVRs (MAF < 0.01) are more likely to overlap with genes, than common CNVRs (MAF ≥ 0.05). The Population differentiation index (Fst) based on CNVRs revealed multiple highly diverged CNVRs between the two breeds. Some of these CNVRs overlapped with candidate genes such as MGAM and ADAMTS17 genes, which are related to starch digestion and body size, respectively. Lastly, linkage disequilibrium (LD) between CNVRs and BovineHD BeadChip SNPs was generally low, close to 0, although common deletions (MAF≥ 0.05) showed slightly higher LD (r2=~0.1 at 10kb distance) than the rest. Nevertheless, this LD is still lower than SNP-SNP LD (r2=~0.5 at 10kb distance). Conclusions Our analyses showed that CNVRs detected using BovineHD BeadChip arrays are likely to be functional. This finding indicates that CNVs can potentially disrupt the function of genes and thus might alter phenotypes. Also, the population differentiation index revealed two candidate genes, MGAM and ADAMTS17, which hint at adaptive evolution between the two populations. Lastly, low CNVR-SNP LD implies that genetic variation from CNVs might not be fully captured in routine animal genetic evaluation, which relies solely on SNP markers. Keywords: Copy number variations, Bos taurus, Linkage disequilibrium, population genetics
Prognostic significance of NDRG2 combined with EGFR patients with lung adenocarcinoma
Authors: Yang Bo , Li Xiao-Ping , Zhou Hong-Gang , Jiang Tao , Xiao Ting , Li Xiao-He , Zhang Liang , Li Lei , Wang Wen-Chen , Zhang Wei-Dong 
Published: November 2019

Abstract
Background: N-myc downstream-regulated gene 2 (NDRG2) plays a substantial role in lung adenocarcinoma (LUAD). Epidermal growth factor receptor (EGFR) mutation could significantly improve prognosis in patients with LUAD. In this study, we aimed to elucidate the prognostic value of NDRG2/EGFR in patients with LUAD. Methods: Immunohistochemistry, Western blotting, and reverse transcription-polymerase chain reaction (RT-PCR) were conducted to detect the expression levels of NDRG2 protein. Association between NDRG2/EGFR expression and clinicopathological characteristics of patients with LUAD was examined as well. Serum level of carcinoembryonic antigen (CEA) was tested prior to treatment of patients with LUAD. Patients’ overall survival was assessed by Kaplan–Meier method. Multivariate Cox regression analysis was carried out to investigate the effects of patients’ demographic characteristics on OS. Results: The expression level of NDRG2 was significantly decreased in patients with LUAD. The expression level of NDRG2 was positively correlated with levels of CEA and EGFR. Advanced stages were significantly associated with low expression level of NDRG2. We found that patients in NDRG2-high/EGFR(+) group had the best outcome, while patients in NDRG2-low/EGFR(-) group had the worst. Meanwhile, Cox regression analysis showed that NDRG2-low/EGFR(+), NDRG2-high/EGFR(+), and vascular invasion were independent prognostic factors of LUAD. Conclusion: The significant prognostic value of NDRG2/EGFR should be highly considered in patients with LUAD.