bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of rigorous nursing training and reinforcement on incidence of thrombophlebitis at tertiary care centre
Authors: Purushothaman Suraj , Patel Kinjal P. , Dalal Dhaval N. , Carwal Trupti N. , Gawali Vijaykumar P. 
Published: July 2020

Background: Peripheral venous cannulation (PVC) is one of the commonest procedures carried out in hospital. It allows rapid and accurate administration of medication. However, there is dearth of formal training to nurses There are few studies which has shown benefits of offering formal training to improve clinical practice and patient care.Methods: In view of rising cases of thrombophlebitis, nurses were trained in hand hygiene, patient skin preparation, wearing gloves and aprons, establishing a clean environmental field, using sterile equipment, disposing of contaminated or soiled equipment and linen appropriately, safe disposal of sharps and adherence to universal precautions. Retrospective, observational, single centre study to analyse data of inpatients for 4 years duration was carried out. This included 2 years data prior to offering nursing training and 2 years post training.Results: There is statistically significant improvement in number of thrombophlebitis event for 2 years prior and 2 years post training. Total events in 2 years prior to training were 63 which reduced to 22 in later 2 years due to nursing training. A p value was 0.0297. Out of total 87 thrombophlebitis incidences, 40 and 47 incidences in males and females respectively were observed. Mean age for men was 58.39 and mean age for female was 52.62 with SD 27.39 and 22.06 respectively.Conclusions: When nurses were trained in patient assessment, Insertion site selection (prefer hand and forearm; to avoid joints and lower limbs), catheter selection, dwell time, early identification of phlebitis and appropriate corrective measures and compliance with best practice guideline, thrombophlebitis rates drastically reduced.
Influence of sleep in polycystic ovarian syndrome: an ayurvedic appraisal
Authors: Vaishnav Mauli , N. R. Navoday Raju 
Published: July 2020

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder which affects the reproductive, metabolic and psychological health of women. Now a day’s incidence rate of PCOS is incising in reproductive age of woman due to sedentary lifestyle and faulty daily routine. Clinical studies indicate that sleep disturbance and disorders including obstructive sleep apnea and excessive daytime sleepiness are more common in the woman with symptoms of PCOS. Despite proof of the high prevalence of sleep disorders in these patients, modification of sleep is not considered as major point for treatment protocol in modern therapeutics. Ayurveda as a holistic medicine lays great emphasis on lifestyle modification under Aahaara (Diet)- Vihaara (Daily regimen)- Oushadha (Medicine) - triad for the prevention and treatment of all diseases. Among Vihaara, Nidra (Sleep) is considered as a very influencing factor in Ayurvedic classics. Balanced sleep at night maintains the health. Disturbance of sleep pattern can lead to Dosha vitiation which hampers regular metabolic activity of the body and leads to various disorders. Hormones affecting metabolism, appetite and blood glucose are regulated with circadian rhythms. When circadian rhythms are out of sync, the body’s metabolic health hampers. Irregular metabolic function disturbs the hormonal cycle including hypothelamo-pitutory-ovarian axis, hypothalamic–pituitary–adrenal function, and so on. These can ultimately lead to PCOS in reproductive age of women. It seems that if lifestyle modification should be expanded in PCOS patients including sleep hygiene alongside food and exercise positive outcome can be obtained. With this background this study is aimed to determine the importance of sleep hygiene in PCOS from the view of Ayurveda.
Dynamics of change of chlorophyll and carotenoid pigments in leaves of Chrozophora tinctoria species spread in Nakhchivan Autonomous Republic (Azerbaijan Republic)
Authors: Khudaverdiyeva Samira F. 
Published: July 2020

<p class="abstract"><strong>Background:</strong> The pigment composition and the dynamics of pigment accumulation were investigated to determine the degree of adaptation of <em>Chrozophora tinctoria </em>to the environmental conditions in the Nakhchivan Autonomous Republic (AR) of Azerbaijan Republic.</p><p class="abstract"><strong>Methods:</strong> The leaves were collected (transects size 5×5 m, in triplicate) and dried with 15-20 pieces, pigments were separated by solvent. The pigment density was determined by the absorption peak on a spectrophotometer, and then the pigment density was calculated. </p><p class="abstract"><strong>Results:</strong> The chlorophyll pigments in the dry weight of leaves varied between 2-6 mg and carotenoids 0.8-1.2 mg/g were found. Also, chlorophyll (a-b) pigments increased in 1.2 times, and carotenoids decreased in 3.6 times depending on environmental conditions.</p><p class="abstract"><strong>Conclusions:</strong> Photosynthetic apparatus of the species actives in all cenosis with response adaptive to changing of environmental conditions depends from the time of leaf collection for the <em>Chrozophora tinctoria </em>species as shown results of researches.</p>
Analysis on the Development Feasibility of a High Quality Antibacterial Medical Material
Authors: Zhang Xinyue , Zhang Rongjia , Cao Minen , Yang Tingxuan 
Published: July 2020

<p>The wet process antibacterial yarn and wet process. Knitted fabric of flax are made by using wet spinning technology and knitting manufacturing technology of flax, test the main properties of yarn and fabric, the research progress of the application of flax products in medical textiles was reviewed. This paper mainly analyzes the feasibility of flax wet process, antibacterial yarn and flax wet process and knitted fabric as flax wet process antibacterial medical materials from two aspects of strength and knitted structure.</p>
THE EFFECT OF MACROECONOMIC VARIABLES ON FISCAL SUSTAINABILITY IN INDONESIA, PERIOD 2004Q1-2018Q4
Authors: Abdullah Muhammad Latif , Sunaryati FNU 
Published: July 2020

Abstract Fiscal sustainability illustrates the condition of a healthy government budget which can finance government spending without increasing debt supply. The purpose of this study is to analyze the impact of macroeconomic variables on fiscal sustainability which in this study fiscal sustainability is proxied as a government budget deficit. The data used in this study is the 2004Q1-2018Q4 time series data using the Vector Error Correction Model (VECM). The results showed that fiscal conditions in Indonesia are sustainable and macroeconomic variables such as domestic debt andinflation has a positive effect on increasing the government budget deficit. Whereas the variable state revenues and foreign debt negatively affect the government budget deficit.Keywords : Fiscal Sustainability, Government Budget Deficit, Domestic Debt, Foreign Debt.
K. I. Abramov’s contribution to the development of the methodology of library history: historical reconstruction
Authors: Pleshkevich E. A. 
Published: July 2020

The article is devoted to the contribution of the famous Russian specialist in library science K. I. Abramov to the methodology of library history, the author of almost 340 publications, of which two-thirds are devoted to history. The importance of his contribution to the development of source studies, historiography, archeography, and library history is emphasized. Based on the principle of historicism and methods of structural analysis, the historical reconstruction of the formation and development of his methodological views was carried out. The external conditions of his formation as a historian are analyzed. It is noted that the formation took place in difficult socio-political conditions. The main conclusions are as follows. The methodological views of K. I. Abramov were based on the relying on archival material, striving to improve the scientific character of historical research, overcoming the desire to reduce research to a superficial presentation and commentary on certain Leninist positions. With his participation, Lenin and Krupskaya’s works on library science were collected and published. At the same time, his worldview was characterized by a dogmatic attitude to Marxism and its methodology, an unconditional adherence to the leading quote, and a non-critical attitude to the statements of the classics of Marxism-Leninism. The Marxist-Leninist doctrine of culture and the library heritage of Lenin and Krupskaya served as a theory in Abramov’s works; the dominance of historical and pedagogical research, which is characterized by following the official interpretation of certain events, simplified presentation of historical processes and events, unambiguity of author’s judgments and assessments, avoiding halftones, exalting achievements while concealing mistakes and failures.The analysis also showed that in the 1990s, under the influence of socio-political changes and rejection of Marxism-Leninism, Abramov revised his attitude to the history of Soviet library construction. He began to focus on the theory of democracy, in the context of which libraries were seen as a vehicle for democracy, and the leading role in library construction was given to the public library movement. He puts forward the concept of democratic library science, which was formed in the period between the February and October revolutions and was rejected by the Bolsheviks.The significance of this study is associated with the generalization of Abramov’s methodological heritage aimed at developing the positive aspects of his methodology, as well as overcoming methodologically incorrect judgments about the history of Soviet library construction.
PERSPEKTIF AL-SYAWKANI TENTANG PENTARJIHAN PERBEDAAN PENAFSIRAN
Authors: Atabik Ahmad 
Published: July 2020

<p class="05Abstrak">Tarjîh dalam penafsiran dihasilkan dari adanya berbagai perbedaan pendapat para mufassir dalam menafsirkan ayat-ayat al-Qur’an. Tujuannya adalah mengetahui pendapat yang paling sahih dan paling layak diterima dalam penafsiran al-Qur’an untuk dapat diamalkan sesuai bidangnya. Tujuan lain, peniadakan kitab-kitab tafsir dari pendapat-pendapat yang janggal dan lemah atau pendapat yang rancu yang disusupkan oleh keyakian mazhab tertentu. Di antara mufassir yang memberi perhatian pada aspek tarjîh dalam penafsirannya adalah Imam al-Shawkânî. Dalam menafsirkan ayat-ayat al-Qur’an, ia tidak cukup hanya menyuguhkan pendapat-pendapat mufassir sebelumnya, melainkan juga melakukan tarjîh terhadap penafsiran-penafsiran itu. Dalam hal ini ia menetapkan seperangkat kriteria dan metode tertentu dalam proses pentarjîh}an terhadap berbagai pendapat yang dikemukakan para ulama. Hasil penelitian ini menemukan bahwa al-Shawkânî dalam mentarjîh perbedaan penafsiran menggunakan metode yang meliputi 1) sîghat (redaksi yang tertentu yang digunakan dalam mentarjîh), 2) teknik tarjîh yang dilakukan al-Shawkânî sendiri dan tarjîh yang diambil dari pendapat ulama’ lain), dan 3) bentuk (tarjîh) dengan naz}âiral-Qur’ân, dengan sunnah, dengan qirâ’ât dan lainnya). Di akhir, makalah ini juga mengeksplorasikan aplikasi dan contoh tarjîh dari metode al-Shawkânî tersebut, dengan tujuan dapat memudahkan bagi pembaca agar lebih jelas memahami metode tarjîhnya.</p>
Anaphylactic Reaction to Tranexamic Acid During Posterior Spinal Fusion
Authors: Plaster Scott , Holy Filip , Antony Antony Kallur 
Published: July 2020

Case:
We present a 20-year-old man who suffered anaphylactic shock during posterior spinal fusion for neuromuscular scoliosis with the offending agent later identified via intradermal testing to be tranexamic acid (TXA).

Conclusion:
TXA, although an increasingly common drug, can be the cause of sudden anaphylactic shock intraoperatively. This now represents the fifth reported case in the literature of patients ranging from 15 years to 80 years old with no previous exposure to the drug.
Is limited aortic resection more justified in elderly patients with type A acute aortic dissection?
Authors: Qin Wei , Su Cunhua , Li Liangpeng , Carmichael Michael , Huang Fuahua , Chen Xin 
Published: July 2020

Abstract
Background: This study compared limited aortic repair (ascending, and /or hemi-arch replacement) versus extended-arch repair (ascending, arch and proximal descending aortic replacement) used for patients aged 65 or older, who had type A acute aortic dissection (AAD), analyzing the influence of the extent of aortic repair on outcomes.Methods: From January, 2001 to December, 2015, 103 patients aged 65 or older underwent operation due to type A AAD in Nanjing First Hospital. The cohort was divided into two subgroups according to the surgical approaches, including limited aortic replacement (LAR, n=41) and total arch replacement + stent elephant trunk implantation (TAR+SET, n=62). Results: There was no significant difference in gender, age, hypertension, diabetes, smoking, PCI history, atrial fibrillation, pericardial effusion, aortic valve insufficiency (≥ moderate), shock situation before operation, and Euro-score II between the two groups except limb malperfusion and tear location. The cross-clamp time, CPB time, intubation time, ICU stay time and hospital time were all significantly less in the LAR group than in the TAR+SET group. A total of 89 patients were discharged home successfully after operation, with a difference of hospital mortality (P=0.04). The overall survival rates at 5-year follow-up were 82.5±6.0% in LAR group and 75.2±5.6% in TAR+SET group, but with no difference (p=0.151). The freedom from adverse aortic events at 5-year was 84.3±6.5% in LAR group versus 97.9±2.1% in TAR+SET group, with a statistical difference (p=0.03). Conclusion: These findings support limited aortic resection is acceptable for elderly patients with type A AAD if surgical principles allow.
Cerebrospinal fluid α-synuclein predicts neurodegeneration and clinical progression in non-demented elders
Authors: Li Jie-Qiong , Bi Yan-Lin , Shen Xue-Ning , Wang Hui-Fu , Xu Wei , Tan Chen-Chen , Dong Qiang , Wang Yan-Jiang , Tan Lan , Yu Jin-Tai 
Published: July 2020

Abstract
Background: Accumulating reports suggest that α-synuclein is involved in Alzheimer disease (AD) pathogenesis. Cerebrospinal fluid (CSF) α-synuclein could be a potential biomarker of AD. We sought to test whether CSF α-synuclein is associated with other AD biomarkers and could predict neurodegeneration and clinical progression in non-demented elders. Methods: Associations were investigated between CSF α-synuclein and other AD biomarkers at baseline in non-demented Chinese elders. The predictive values of CSF α-synuclein in longitudinal neuroimaging change and conversion risk of non-demented elders were assessed using linear mixed effects models and multivariate Cox proportional hazard models, respectively, in Alzheimer's disease Neuroimaging Initiative (ADNI) database.Results: We detected that CSF α-synuclein levels correlated with AD-specific biomarkers CSF total tau and phosphorylated tau levels in 651 Chinese Han participants (training set). These positive correlations were replicated in ADNI database (validation set). Using a longitudinal cohort from ADNI, CSF α-synuclein concentrations increased with disease severity. CSF α-synuclein had high diagnostic accuracy for AD based on the “ATN” system (A+T+) vs controls (A-T-) (area under the receiver operating characteristic curve, 0.84). Moreover, CSF α-synuclein predicted longitudinal hippocampus atrophy and conversion from MCI to AD dementia.Conclusions: CSF α-synuclein is associated with CSF tau levels and could predict neurodegeneration and clinical progression in non-demented elders. This finding indicates CSF α-synuclein is a potentially useful, early biomarker for AD.
Modified Nodal Stage of esophageal cancer based on the evaluation of the hazard rate of the negative and positive lymph node
Authors: Zhang Jinling , Li Hongyan , Zhou Liangjian , Yu lianling , Che Fengyuan , Heng xueyuan 
Published: July 2020

Abstract
Objective: The study aimed to propose a modified Nodal stage of esophageal cancer (EC) on basis of the number of positive lymph node (PLN) and the number of negative lymph node (NLN) simultaneously. Method: Data from 13,491 patients with EC registered in the SEER database were reviewed. The parameters related to prognosis were investigated using a Cox proportional hazards regression model. A modified N stage was proposed based on the cut-off number of the re-adjusted ratio of the number of PLN (numberPLN) to the number of NLN (numberNLN), which were derived from the comparison of the hazard rate (HR) of numberPLN and numberNLN. The modified N stage was confirmed using the cross-validation method with the training and validation cohort, and it was also compared to the N stage from the American Joint Committee on Cancer (AJCC) staging system (7th edition) using Receiver Operating Characteristic (ROC) curve analysis.Results: The numberPLN on prognosis was 1.064, while numberNLN was 0.962. The modified N stage was defined as follows: N1 stage: the ratio range was from 0 to 0.08; N2 stage: more than 0.08, but no more than 0.63; N3 stage: more than 0.63. Cross-validation method within the cohort identified the predictive accuracy of this modified N stage, and ROC curve analysis demonstrated the relative superiority of the modified N stage over that of the AJCC N stage.Conclusion: The modified N stage based on the re-adjusted ratio of numberPLN to numberNLN can evaluate tumor stage relative accurately than the traditional N stage.
WITHDRAWN: An Integrated Process of Methanol Coagulation and Side Stream Membrane Bioreactor for Treatment of Rice Gruel Wastewater
Authors: Nazia Shaik , Mishra Karishma , Jegatheesan Veeriah , Bhargava Suresh K , Sundergopal Sridhar 
Published: July 2020

Abstract
The demand for water supply is expected to be raised significantly in forthcoming decades. Production of reusable water from industrial and domestic wastewater is a feasible, cost effective and significant positive benefit to the environment. In the present study, the domestic rice gruel wastewater (RGW) was treated with aqueous methanol coagulation integrated aerobic membrane bioreactor (AMBR). Initially, the RGW which is at room temperature was treated with spiral wound hydrophilized - ultrafiltration (HF – UF) 5 kDa membrane module to determine the removal efficiency. Furthermore, the RGW was pre-treated with various coagulants such as methanol, ethanol and HCl. The obtained pre-treated RGW was subjected to the HF – UF 5 kDa side stream AMBR for production of reusable water. The experiments were conducted to determine the turbidity, conductivity, total dissolved solids (TDS) and chemical oxygen demand (COD) were found to be 96 %, 91 %, 91 % and 94.6 %. The overall process was feasible, compact, environmental free, cost effective, eco-friendly.
Facts and Reflections on Initial Public Health Emergency Response to SARS and COVID-19 Pandemics in Mainland China: A Retrospective Comparative Study
Authors: Zhu Huanhuan , Wang Qian , Zhang Tiantian , Liu Xin , Dai Ruiming , Wu Ping , Bai Ge , Wang Ying , Zhou Ping , Luo Li 
Published: July 2020

Abstract
Background: Since December 2019, 2019-nCoV has emerged in Wuhan, China, the fast pace of transmission is wreaking global public health crisis. Country’s reaction speed is critical for the control of public health emergency (PHE), especially in the early stage of an outbreak. Compared with SARS pandemic, whether has the efficiency of initial public health emergency response to COVID-19 in mainland China been improved? And whether is there still existing vulnerabilities in current PHE system? Studies on this topic are relatively few. We tried to find the answers, evidences and alternatives. Methods: We conducted a retrospective comparative study. The speed of hospital reporting, pathogen identification and government decision-making between SARS and COVID-19 were compared by selecting 5 critical events from initial public health emergency response timeline. Besides, combining with the two pandemics' progress curves, we discussed the characteristics of their peak time.Results:(1) SARS completed the entire initial public health emergency response in 127 days, and COVID-19 completed in 44 days. Response speed has been shorted nearly by 3 times. (2) Both the first SARS and COVID-19 cases were reported in 19 days. It doesn't appear that hospital reporting speed becomes faster. (3) The accumulated time completing pathogen identification were 118 days for SARS and 31 days for COVID-19. The speed has been improved by more than 3 times. (4) 9 days after the completion of pathogen identification, national government made emergency policies for SARS while the interval between pathogen identification and national government's decision-making for COVID-19 was 13 days. (5) The peak time of SARS came about 80 days later than that of COVID-19. But both the two pandemics' peak occurred about 20 days after the national government's decision-making, and then the curves went down dramatically.Conclusions: The speed of initial public health emergency response to pandemic has been improved due to faster identification. However, some deficiencies and challenges in early alert and authorities' decision-making still remain. Therefore, Chinese government should put more stress on improving hospital's sensitivity to new emerging infectious diseases and timeliness of government's decision-making.
Nerve Growth Factor is Closely Related to Glucose Metabolism, Insulin Sensitivity and Insulin Secretion in the Second Trimester: A Case-Control Study in Chinese
Authors: Tang Mengyang , Luo Mingjuan , Lu Wenqian , Zhang Rong , Liang Wei , Gu Jianfen , Yu Xuemei , Zhang Xueli , Hu Cheng 
Published: July 2020

Abstract
Objective: Inflammation-related factors have been shown to play a significant role throughout pregnancy. In this study, we aimed to explore the relationships between selected inflammatory cytokines and gestational diabetes (GDM) in Chinese pregnant women.Design and Methods: This was a 1:1 matched case-control study that included 200 pairs of subjects in the second trimester and 130 pairs of subjects in the third trimester. Serum levels of nerve growth factor (NGF), Interleukin-6 (IL-6), leptin, Interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNF-α) and Interleukin-1beta (IL-1β) were measured by enzyme immunoassay. The associations of these inflammatory factors with metabolic parameters were analysed.Results: In the second trimester, GDM patients had higher NGF levels and lower IL-8 levels than did normal controls (P<0.001 and P=0.015, respectively). However, in the third trimester, only lower leptin levels were observed in the GDM group (P=0.031). Additionally, in the second trimester, NGF levels were not only positively associated with fasting, 1-h and 2-h glucose levels and the area under curve of glucose (AUCG), but also positively related to insulin sensitivity and secretion, as suggested by fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR) and homeostasis model assessment index of β-cell secretion (HOMA-β) (all P<0.05). Moreover, IL-6 and leptin levels were positively correlated with HOMA-IR and HOMA-β, and TNF-α levels were positively related to HOMA-IR (all P<0.05). Except for the relationships between NGF and HOMA-β and TNF-α and HOMA-IR, the other correlations still existed even after adjusting for confounding factors (all P< 0.05). Conclusion: In addition to the positive associations of IL-6 and leptin with insulin resistance and secretion, NGF was higher in the GDM patients and strongly linked to glucose metabolism, insulin resistance and pancreatic β cell function in Chinese pregnant women in the second trimester.