bluuebunny/crossref_metadata_2025_split huggingface dataset:
Traumatic Boutonnière Deformity of the Thumb
Authors: García-Jiménez Antonio , Uran Bernardo , Ochoa Javier 
Published: November 2020

AbstractTwo Cases Of Boutonnière Deformity After Trauma Are Presented In Patients Without Rheumatic Disease. One Of Them Suffered An Assault and the other a high-energy accident. Both cases were misdiagnosed. The first case presented an injury of the dorsoradial capsule of the metacarpophalangeal (MCP) joint and the second case presented an injury of the adductor pollicis (AP) which is an unusual finding regarding this kind of deformity. The surgical treatment failed up to two times in the first case hile in the second case it failed once.
Metástasis bilateral de húmero, en paciente con cáncer renal, tratado con inmunoterapia y cirugía. Reporte de un caso
Authors: Reyes Andrés Calvo , Valenzuela Alfonso , Montegu Roberto , Rieutord Juan Pablo 
Published: November 2020

ResumenEl carcinoma de células renales es el 7mo cáncer en frecuencia a nivel mundial con más de 300.000 casos nuevos al año y es la 3era malignidad genitourinaria más frecuente.El sitio más común de metástasis es el pulmón mientras que el esqueleto ocupa el segundo lugar con una frecuencia que varía entre un 20% a un 35%. Se ha reportado una sobrevida de 12 meses en promedio luego de la aparición de metástasis óseas.Reporte del caso de un paciente con diagnóstico de cáncer renal de células claras y metástasis óseas (en columna, pelvis y ambos húmeros), que evoluciona con fractura de ambos brazos. El paciente es aceptado en un ensayo clínico de tratamiento con inmunoterapia y además se somete a una reducción y osteosíntesis bilateral de húmero con clavo endomedular, logrando la consolidación de ambas fracturas y, por ende, la regresión de la enfermedad.
Barium Defaecating Proctography: Experience from a Tertiary Referral Center
Authors: Wan Chew Cindy Sze , Yeap Elaine Ee-Min , O’Dwyer Patrick J. 
Published: November 2020

Abstract
Objective Pelvic floor dysfunction (PFD) is a major health care problem predominately affecting the elderly female. It impairs quality of life and patients increasingly expect a solution. Barium defaecating proctography (BDP) is frequently used in the assessment of patients with PFD. The aim of this study was to present our findings from BDP and to look at the proportion of patients who went on to have surgery following their investigations.
Methods All patients who underwent BDP in a tertiary referral center were identified retrospectively from the computerized radiology information system. Demographic data and radiologic findings were extracted. Data regarding those who had surgery were retrieved from the anonymized patient registry.
Results A total of 671 patients had a BDP during the study period. The main symptoms investigated were obstructed defecation or chronic constipation (64%). Complete barium evacuation was observed in 70% of the patients, while 17% were noted to have incomplete and 13% no evacuation. A large rectocele (>5 cm) was noted in 38% while nearly 5% had frank prolapse. There was no significant association between a rectocele and any of the presenting symptoms. Seventy-eight (12%) patients went on to have operation, of which 17 (22%) had multiple procedures. Three patients ended up with a permanent stoma.
Conclusion BDP contributes to decision making in patients with PFD. However, results need to be interpreted with caution and in conjunction with other tests and clinical examination to maintain a low rate of operation and reduce the risk of adverse outcomes for these patients.
Endometriosis: A Clinicopathological Study in a Tertiary Care Hospital
Authors: Bhat Shubha P. , Kaliyat Sajitha , Laxminarayana Kishan Prasad Hosapatna , Srinivas Teerthanath , Venugopala Krishna Prasad Holalkere , Shetty Jayaprakash Kubalady 
Published: November 2020

AbstractBackground Endometriosis (EM) is an estrogen-dependent disease characterized by the presence of endometrial gland and stroma outside the uterus. It is commonly seen in the reproductive age group and is a leading cause of infertility. Patients present with chronic pelvic pain, menstrual abnormalities, dyspareunia, or mass per abdomen. Surgical excision is the treatment of choice with postoperative medications and progesterone agents.Aims and Objectives This study aims at determining the distribution of EM in terms of age, parity, symptoms, site, morphological features. We also analyzed the management of EM in these cases.Methodology This is a retrospective study done in a tertiary care hospital in Mangalore, India. The case records of 77 histopathologically confirmed cases of EM during the 7 years between June 2012 and May 2019 were studied. Demographic profiles, parity, presenting complaints, site of the lesion, morphological features, treatment given, follow-up, and recurrence were noted and analyzed.Results Of the 77 patients with EM, the most common age group was the fourth decade (40%). The majority (31, 40.25%) of the patients in this study were nulliparous. Chronic pelvic pain was the most common symptom. The most frequent site was ovary.Conclusion The most frequent site of EM is ovary, leading to infertility. With the advent of laparoscopy, early diagnosis and excision have been feasible. The histopathological examination should be done for confirmation. Awareness of this disease among health care professionals is necessary whenever a woman in reproductive age presents with chronic pelvic pain and infertility.
Safety and Efficacy of Apixaban For Therapeutic Anticoagulation in Critically Ill ICU Patients with Severe COVID-19 Respiratory Disease
Authors: Wenzler Eric , Engineer Monaz H. , Yaqoob Maidah , Benken Scott T. 
Published: November 2020

AbstractIntroduction Despite the use of unfractionated heparin (UFH) or low molecular weight heparin (LMWH), rates of thromboembolic disease, and subsequent morbidity and mortality remain unacceptably high in patients with severe novel coronavirus disease 2019 (COVID-19) disease. Direct oral anticoagulants (DOACs), such as apixaban, have numerous purported benefits although the safety and efficacy of their use in intensive care unit (ICU) patients with severe COVID-19 has yet to be evaluated.Materials and Methods Single-center, retrospective cohort study of 21 ICU patients with severe COVID-19 respiratory disease treated with apixaban for atrial fibrillation (AFib), venous thromboembolism (VTE), catheter-induced thrombosis, and/or COVID-19-induced coagulopathy. The primary objective was to evaluate the incidence of bleeding events and secondary objectives included thromboembolic events, coagulation parameters, and mortality.Results Ninety percent of patients were non-White, 43% were obese, 90% had acute respiratory distress syndrome, and 76% required mechanical ventilation. Nearly half of (47.6%) also experienced renal dysfunction and required renal replacement therapy. Eighty-six percent of patients received prophylaxis or treatment with UFH or LMWH within the 24-hour period prior to apixaban initiation. Patients were initiated on apixaban for the treatment of suspected or confirmed VTE (67%) or AFib (33%). All coagulation parameters remained abnormal but stable throughout the 10-day monitoring period. No patients experienced any major bleeding events or thrombosis throughout the study period. There were four deaths during the follow-up period, all deemed unrelated to coagulopathy or bleeding.Conclusion Apixaban appeared safe and efficacious in ICU patients with severe COVID-19 disease. These data encourage future trials seeking to optimize anticoagulation strategies in patients with severe COVID-19.
Image of the Month: How to Select the Ideal Surgical Approach in Male Anorectal Malformation with No Visible Fistula
Authors: Apte Anisha , McKenna Elise , Levitt Marc A. 
Published: November 2020

AbstractWe present a case of a 6-month-old male infant with an anorectal malformation (ARM) who underwent colostomy as a newborn, and now presents for definitive repair. A colostogram is shown to identify the malformation and to help plan for the ideal surgical approach. The case is presented with a focus on surgical strategies for management of ARM in the male infant, with questions for the readers posed in a quiz format.
Cellular pathways of calcium transport and concentration toward mineral formation in sea urchin larvae
Authors: Kahil Keren , Varsano Neta , Sorrentino Andrea , Pereiro Eva , Rez Peter , Weiner Steve , Addadi Lia 
Published: November 2020

Significance
Organisms form mineralized skeletons, many of which are composed of calcium salts. Marine organisms extract calcium ions from sea water. One of the main unresolved issues is how organisms concentrate calcium by more than three orders of magnitude to achieve mineral deposition in their skeleton. Here we determine the calcium state in each of the calcium-containing vesicles inside the spicule-building cells of sea urchin larvae. We show that within one cell there is a wide range of concentrations and states from solution to solid. We hypothesize that calcium concentration increases gradually in each vesicle, starting from seawater levels and until mineral is deposited. This model might well be relevant to other phyla, thus advancing the understanding of biomineralization processes.
Race and ethnic variation in college students’ allostatic regulation of racism-related stress
Authors: Cheadle Jacob E. , Goosby Bridget J. , Jochman Joseph C. , Tomaso Cara C. , Kozikowski Yancey Chelsea B. , Nelson Timothy D. 
Published: November 2020

SignificanceRacial resentment, antiimmigration sentiment, and hate crimes, including on college campuses, have increased recently. Although African American (70%) and Hispanic/Latinx people (56%) report considerable discrimination exposure, there remains a critical need for research examining the pathways through which racism-related stress affects health. Here, we developed an ecological, intensive longitudinal design leveraging an independent biosignal of stress arousal collected from a wearable sensor. Our method documents both increased simultaneous negative emotion and stress arousal among African American, Latinx, and African students in response to racism-related stress. These findings provide support for allostasis-based theories of mental and physical health via a naturalistic assessment of emotional and physiological responding to real-life social experiences.
Gender stereotypes can explain the gender-equality paradox
Authors: Breda Thomas , Jouini Elyès , Napp Clotilde , Thebault Georgia 
Published: November 2020

Significance
Recent research has found that the strong underrepresentation of women in math-related fields is more pronounced in more egalitarian and more developed countries. This pattern has been called the “gender-equality paradox.” We show that stereotypes relating math primarily to men are actually stronger in more egalitarian and more developed countries and that they mediate the link between development and segregation across fields of study. The mechanisms connecting socioeconomic development to the strengthening of these stereotypes and the gendering of math-related fields are discussed. Results suggest that gender occupational segregation can be reduced but will not decrease by itself as societies become more developed. Appropriate policies are therefore needed to limit this segregation or its impact on gender inequality.
A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I
Authors: Ebenhoch Rebecca , Prinz Simone , Kaltwasser Susann , Mills Deryck J. , Meinecke Robert , Rübbelke Martin , Reinert Dirk , Bauer Margit , Weixler Lisa , Zeeb Markus , Vonck Janet , Nar Herbert 
Published: November 2020

Significance
We present a comprehensive structural study, which shows the human GCH1 and GCH1−GFRP complexes in all states (apo, ligand bound, partially and fully inhibited). We observed local rearrangements in the allosteric pocket upon BH4 binding, which result in drastic changes in the quaternary structure of the enzyme leading to a more compact, tense form in the inhibited protein. Inhibition of the enzymatic activity is not a result of hindrance of substrate binding, but rather a consequence of accelerated substrate binding kinetics as shown by STD-NMR and site-directed mutagenesis. We propose a dissociation rate-controlled mechanism of allosteric, noncompetitive inhibition, which could stimulate further research toward the development of GCH1 inhibitors to treat neuropathic and inflammatory pain disorders.
The Determination Analysis Of Telecommunications Customers Potential Cross-Selling With Classification Naive Bayes And C4.5
Authors: Purnamasari I , Handayanna F , Arisawati E , Dewi LS , Sihombing E G , Rinawati  
Published: November 2020

Abstract
Every company has various marketing strategies. Marketing strategies are offered to sell the company’s products to benefit if the company introduces new products. However, too many offers to customers that are not true, will only make marketing inefficient and ineffective. Data mining as a way to find patterns and relationships in data can be used to make valid predictions. To simplify the marketing strategy of PT. TELKOM then classifies the data that already exists in PT. TELKOM Jakarta. Telkom customers have the potential to become customers of new Indihome products, so marketing is carried out by PT. TELKOM has become more effective and efficient. By using data mining classification methods, namely the Naive Bayes Classifier algorithm and the C4.5 algorithm, patterns and relationships are obtained to simplify the marketing strategy of PT. TELKOM where in previous research, the results of classification of data mining research models with the Naive Bayes Classifier algorithm have an accuracy value of 85.08% and AUC 0.841 while in this study the C4.5 algorithm has an accuracy value of 88.61% and AUC 0.870. C4.5 is a model with good accuracy for customer classification data that has the potential for more effective and efficient in cross-selling marketing strategy..
User satisfaction of covid19 Kota Bogor website using webqual 4.0
Authors: Andrian A , Cakrawijaya S R , Riana D , Palasara N , Riyandi A , Rusdi I 
Published: November 2020

Abstract
Nowadays E-Government has a huge impact on supporting and running governments around the world. And a government site is a tool for interacting between the government and its citizens. Recent studies have shown that the quality of the website becomes something that the government mandatory. This research examines the overall quality of the website Covid19 Bogor City. Using the Webqual methodology to assess the quality of the website and to see how the Bogor city government maintains the expectations of its citizens or users. From a three-dimensional variable that has been given by webqual and from 119 respondents as a sample of this research, the author finds that all three variables have significant results for the satisfied citizens or users with certain aspects of the facilities, contents, and menus of the website. Majority respondents who have accessed and using the website of Bogor City Covid19 satisfied with the facilities.
Application of Fuzzy Multy Attribute Decision-Making Method in Decision-Making System for Determining The Provision of Achievement Scholarship in SMPN 1 Simpati
Authors: Ilham Wanda , Putri Tiara Eka , Sokibi Petrus , Kusnadi  
Published: November 2020

Abstract
This study aims to predict students who are entitled to receive scholarships, the results of this study can be used to accept decisions for scholarship recipients by looking at the report cards, the method used in this study uses the FMADM method, in predicting the results obtained, receiving scholarships by looking at several suggestions such as average grades, Parents ’income, siblings, parents’ answers. The results of FMADM calculations have actual taking values, so these values can be used to make decisions as to who is eligible to receive a scholarship.
Data Mining Technique to Determine the Pattern of Fruits Sales & Supplies Using Apriori Algorithm
Authors: Hermaliani Eni Heni , Kurniawati Laela , Haryanti Tuti , Mutiah Nisa , Kurniawan Aan , Renhoran Bahrun Said 
Published: November 2020

Abstract
Advances in technological developments in the current 4.0 era require retail businesses to increase sales and develop marketing strategies. Determination of which products are widely sold and which products will be propagated in inventory is very important for retail businesses to prevent data accumulation. Data Mining has been widely used to conduct analysis, determine patterns and associations. In this paper, we propose a basic methodology for calculating association analysis with apriori algorithms used to process the most sold products and which products will be propagated in the sales inventory. The results of this study are the calculation model of high-frequency pattern analysis and the formation of association rules and item set combination patterns resulting from the sale of fruit products from retail with the highest support and confidence of the most sold fruit products. Therefore the apriori algorithm can help develop sales strategies.
Identification of Disease and Efforts to Protect Native Orchid Plants Against Bacteria Infection in Liwa Botanical Garden
Authors: Mahfut  , Anggreiny Anggi , Wahyuningsih Sri , Handayani Tundjung Tripeni , Sukimin  
Published: November 2020

Abstract
Liwa Botanical Garden is located in West Lampung Regency and is one of the conservation of ornamental plants that presents the rich flora of the Bukit Barisan Selatan National Park. One of the flagship collections of this botanical garden is a natural orchid. Until now, disease infections are still a major obstacle in efforts to preserve and develop the potential of natural orchids. Based on previous research, it is known that several individual orchid collections from Liwa Botanical Garden show symptoms of bacterial infection. This pathogen will infect orchids and cause soft rot disease. This research was conducted to determine the identification of diseases and efforts to protect natural orchids against bacterial infections in the Liwa Botanical Garden through a collection of samples that showed symptoms of infection, analysis of disease symptoms, and analysis of disease resistance levels. The results showed that the response of the natural orchids of Liwa Botanical Garden to bacterial infections was to show symptoms of soft rot disease, i.e Bulbophyllum sp., Dendrobium crumenatum, Dendrobium montanum, Pholidota sp., and Vanilla sp. The type of orchid that shows the most symptoms of bacterial infection is Vanilla sp. 11 samples, and Pholidota sp. and Dendrobium crumenatum with 3 samples each. The type of orchid that shows the most symptoms is Flickingeria sp. a total of 8 samples. The natural type of the Liwa Botanical Garden which is most susceptible to bacterial infections is Pholidota sp. and Vanilla sp. with disease intensity of 10% and 7.7%. The results of this activity are expected to be basic information in efforts to protect plants against diseases to support the application of conservation of natural orchids in Liwa Botanical Garden.
Taxonomy Genetic Algorithm For Implementation Partially Mapped Crossover In Travelling Salesman Problem
Authors: Hardi SM , Zarlis M , Effendi S , Lydia M S 
Published: November 2020

Abstract
Genetic algorithmhasvarious process are carried out to get optimal results in solving the problem of traveling salesman problemTravelling salesman problem (TSP) as known as combinatorial NP problem. Salesman given a map that he has accomplished all cities only once by minimized the total of distance and he has to return to the first city. By describing the taxonomy in genetic algorithm, it can avoid confusion in understanding the various classifications that exist in the genetic algorithm operator. This paper explains one of the parts from genetic algorithm is crossover. Crossover being important step in genetic algorithm. Commonly mechanism crossover replaces two selected chromosome which part from two parent’s individual randomly position, generate random number interval 0-1. Crossover occur for each individual by determining the probability of the crossover. If the probability crossover is smaller than random number, there is no crossover process. Partially mapped crossover is part of the taxonomy of genetic algorithms whose implementations can be applied in a variety of problem solving including in the travelling salesman problem. The test results of this researchusing pc 0.25 and pm 0,1 with tsp eil51 data, it was found that the optimal route average value was 4069.34 and the best fitness average was 2.46E-04, while for the eil76 test data the optimal route average value was 6844.4. and the average best fitness value of 1.46E-04.
Production Risk with Feasible Generalized Least Square
Authors: Ferdushi Kanis Fatama , Hossain Md Kamrul , Kamil Anton Abdulbasah 
Published: November 2020

Abstract
This study investigates production risk. A multistage stratified random sampling technique was adopted to select sampling unit. In between Cobb Douglas and Linear quadratic model, the linear quadratic model had been picked through feasible generalized least square method. The numerical model, we utilize the information from rice cultivating in Bangladesh. The results show that uneven socioeconomic and farm-specific inputs are creating risk in rice production. Input variables such as area, labour, and fertilizer and managerial factors, for example, experience, schooling, contact with extension, training, natural calamity, member and status indicated a significant impact on rice productions uncertainty. This indicated that both input and managerial factors were important for the rice production.
Research on Processes of Service-oriented Teaching Quality Management Based on Big Data
Authors: Zhu Yang , Liu Hongcheng 
Published: November 2020

Abstract
The management of teaching quality is subordinate to and serves the main teaching activities of colleges and universities, which is an important means to improve the teaching quality. Today, we can make college teaching quality management more dynamic, accuracy and objectivity with the gradual construction of big data environment. We can maintain the right direction and achieve the best results of teaching activities in the continuous rectification give full play to its service function by reasonable evaluation, scientific prediction and effective intervention. This paper focuses on three key issues of evaluation, prediction and intervention in the construction of service-based teaching quality management system, discusses the main contents, process and methods related to teaching evaluation, and lays a theoretical foundation for the realization of service-based teaching quality management system in the big data environment.
RETRACTED: A SIFT-FREAK Based Framework for Coastline Image Stitching
Authors: Wu Xiaoyu , Chen Gong , Ding Xiangqian , Xie Kezhen , Wei Guanqun 
Published: November 2020

Abstract
The quality of the images collected by the coastal zone video surveillance equipment is seriously degraded due to the sea fog, which directly affects the analysis of the image. Therefore, the study of the costal image dehazing method is of great significance to the related research of the coastal zone. Costal image has the characteristics of large sky area and monotonous color. The traditional method based on atmospheric scattering physics model is not suitable for this kind of image for block effect and color distortion. In this paper, we introduce the generative adversarial mechanism into sea fog image defogging, and propose a coastal image dehazing network based on it. The proposed model includes a generative network and a discriminative model, and is trained by adversarial mechanism. The generative model is composed of multi-scale feature extraction module and residual connection module. The discriminative network consists of two sub-networks of receptive field of different sizes.