bluuebunny/crossref_metadata_2025_split huggingface dataset:
Keeping the body in mind: A qualitative analysis of the experiences of people experiencing first‐episode psychosis participating in a lifestyle intervention programme
Authors: Watkins Andrew , Denney‐Wilson Elizabeth , Curtis Jackie , Teasdale Scott , Rosenbaum Simon , Ward Philip B. , Stein‐Parbury Jane 
Published: December 2019

AbstractThe life expectancy gap experienced by people living with severe mental illness is primarily a result of cardiometabolic disease that is often exacerbated by side effects of antipsychotic medication. Commencement of atypical antipsychotic medication is commonly associated with weight gain. The Keeping the Body in Mind programme has demonstrated that early intervention with lifestyle activities can attenuate this weight gain and potentially improve long‐term health outcomes. The aim of this study was to explore the experiences of young people who participated in the Keeping the Body in Mind programme, a targeted lifestyle intervention programme. A qualitative approach was used employing a semi‐structured interview format. The interview schedule included questions related to four topics: aspects of the programmes that were useful, attributes of staff members that influenced the programme, changes in attitudes towards their own physical health, and suggestions for programme improvements. Interviews were recorded with duration ranging from 40 to 65 min. Thematic analysis was used to detect and assemble codes. These were then synthesized and classified into themes. Eleven participants were interviewed (seven males), aged between 18 and 25 years. Thematic analysis revealed four main themes: the role of physical health in mental health recovery; the importance of staff interactions; the value of peer interaction; and graduation to a sustainable healthy lifestyle. Study participants reported that they valued the programme for both their physical health and mental health recovery.
The old‐age pension law in Mexico: The promise of poverty in old age?
Authors: Colín Francisco 
Published: December 2019

AbstractIn 1997, Mexico replaced its main old‐age pension system with an individual capitalization system. In 2021, the first people subject to the new system will retire. Using a model that projects demographic and labour variables and using Monte Carlo simulations, the findings of this study show that in 2051 the percentage of men not having a pension will increase from 38 per cent to 59 per cent, and that of women from 44 per cent to 66 per cent. The replacement rate for the average Mexican worker will fall from 70 per cent to 30 per cent. The numbers of people in extreme poverty will increase by almost 2.8 million, representing 9.44 per cent of the population. Alternative scenarios are proposed that involve increasing the contribution rate and raising the retirement age.
Whole exome sequencing identified a homozygous novel variant in CEP290 gene causes Meckel syndrome
Authors: Zhang Rui , Chen Shaoyun , Han Peng , Chen Fangfang , Kuang Shan , Meng Zhuo , Liu Junnian , Sun Ruliang , Wang Zhiwei , He Xiaohong , Li Yong , Guan Yuanning , Yue Zhengfang , Li Chen , Kumar Dey Subrata , Zhu Yuanfang , Banerjee Santasree 
Published: December 2019

AbstractMeckel syndrome (MKS) is a pre‐ or perinatal multisystemic ciliopathic lethal disorder with an autosomal recessive mode of inheritance. Meckel syndrome is usually manifested with meningo‐occipital encephalocele, polycystic kidney dysplasia, postaxial polydactyly and hepatobiliary ductal plate malformation. Germline variants in CEP290 cause MKS4. In this study, we investigated a 35‐years‐old Chinese female who was 17+1 weeks pregnant. She had a history of adverse pregnancy of having foetus with multiple malformations. We performed ultrasonography and identified the foetus with occipital meningoencephalocele and enlarged cystic dysplastic kidneys. So, she decided to terminate her pregnancy and further genetic molecular analysis was performed. We identified the aborted foetus without postaxial polydactyly. Histological examination of foetal kidney showed cysts in kidney and thinning of the renal cortex with glomerular atrophy. Whole exome sequencing identified a novel homozygous variant (c.2144T>G; p.L715*) in exon 21 of the CEP290 in the foetus. Sanger sequencing confirmed that both the parents of the foetus were carrying this variant in a heterozygous state. This variant was not identified in two elder sisters of the foetus as well as in the 100 healthy individuals. Western blot analysis showed that this variant leads to the formation of truncated CEP290 protein with the molecular weight of 84 KD compared with the wild‐type CEP290 protein of 290 KD. Hence, it is a loss‐of‐function variant. We also found that the mutant cilium appears longer in length than the wild‐type cilium. Our present study reported the first variant of CEP290 associated with MKS4 in Chinese population.
Pre‐orogenic upper crustal softening by lower greenschist facies metamorphic reactions in granites of the central Pyrenees
Authors: Airaghi Laura , Bellahsen Nicolas , Dubacq Benoît , Chew David , Rosenberg Claudio , Janots Emilie , Waldner Maxime , Magnin Valérie 
Published: December 2019

AbstractPre‐kinematic greenschist facies metamorphism is often observed in granites and basement units of mountain belts, but rarely dated and accounted for in orogenic cycle reconstructions. Studying pre‐kinematic alteration is challenging because of its usual obliteration by subsequent syn‐kinematic metamorphism often occurring at conditions typical of the brittle–ductile transition. It is, however, to be expected that pre‐kinematic alteration has major implications for the rheology of the upper crust. In the 305 Ma‐old Variscan basement of the Bielsa massif (located in the Axial Zone of the Pyrenees), successive fluid–rock interaction events are recorded in granites below 350°C. Combined microstructural and petrographic analysis, low‐T thermobarometry and in situ U–Th/Pb dating of anatase, titanite and monazite show extensive pre‐orogenic (pre‐Alpine) and pre‐kinematic alteration related to feldspar sericitization and chloritization of biotite and amphibole at temperatures of 270–350°C at 230–300 Ma. This event is followed by a second fluid–rock interaction stage marked by new crystallization of phyllosilicates at 200–280°C and is associated with the formation of mylonitic shear zones and fractures parallel to the shear planes. U–Pb anatase and monazite ages as well as the microtextural relationships of accessory minerals suggest an age for this event at 40–70 Ma, consistent with independent regional geology constraints. The Variscan basement was therefore softened at late to post‐Variscan time, at least 150–200 Ma before the main Alpine shortening while Alpine‐age compression (c. 35–50 Ma) leads to the formation of a dense net of mylonites. The associated deformation, both distributed at the scale of the Bielsa massif and localized at decametric scale in mylonitic corridors, precedes the strain localization along the major thrusts of the Axial Zone. The Bielsa massif is a good example where inherited, pre‐orogenic upper crustal softening controls the deformation patterns in granitic basement units through low‐grade metamorphic reactions.
How to best utilize the line of ligaments and the surface volume coefficient in facial soft tissue filler injections
Authors: Casabona Gabriela , Bernardini Francesco P. , Skippen Brent , Rosamilia Gianna , Hamade Hassan , Frank Konstantin , Freytag David L. , Sykes Jonathan , Onishi Emy C. , Cotofana Sebastian 
Published: December 2019

AbstractBackgroundRecent advances in facial anatomy have increased our understanding of facial aging and where to best position facial soft tissue fillers.AimAim of this study was to investigate a novel injection protocol which makes use of concepts like the line of ligaments or the surface ‐ volume coefficient.Materials and MethodsA total of 306 Caucasian patients (270 females, mean age 45.1 ± 11.4 years; 36 males, mean age 45.9 ± 11.6 years) were retrospectively investigated after the injection following a standardized protocol. This protocol comprised a total of six boluses and one retrograde fanning injections in the infraorbital area utilizing a 22G and a 25G blunt‐tip cannula, respectively. Medial midfacial distances were measured using skin surface landmarks and compared after the injection of the partial and the total algorithm.ResultsDistances between the dermal location of the lateral SOOF and the dermal location of the mandibular ligament increased by 0.17 ± 0.11 mm with P < .001, to the corner of the mouth by 0.20 ± 0.09 mm with P < .001 and to the nasal ala by 0.20 ± 0.11 mm with P < .001. The repositioning of the facial soft tissues resulted also in a decrease of the height of the lower eyelid by 0.49 ± 0.13 mm with P < .001.ConclusionThe results revealed that utilizing these novel anatomic concepts, a mean amount of 0.32 cc high G‐prime soft tissue filler injected in the lateral SOOF can change midfacial distances by an average of 0.19 mm.
Clinical evidences of benefits from an advanced skin care routine in comparison with a simple routine
Authors: Messaraa Cyril , Robertson Nicola , Walsh Melissa , Hurley Sarah , Doyle Leah , Mansfield Anna , Daly Lorna , Tansey Claire , Mavon Alain 
Published: December 2019

AbstractBackgroundThe use of a skin care routine is commonly promoted by the cosmetic industry, yet there is a lack of clinical evidence to support this practice over the use of a single skin care product.AimsIn the present study, we aimed at showing the clinical benefits of using a comprehensive skin care routine vs a simple one.MethodsSkin micro‐/macro‐topographic, skin color, and superficial/deep hydration were collected at baseline and after 4 weeks of use, on forty‐nine women randomly allocated to two groups. The first one followed the use of an advanced routine (AR: Cleanser/Toner/Eye cream/Serum/Day & Night cream), while the other group was instructed to use a simple routine (SR: Cleanser & Day cream).ResultsHemoglobin heterogeneity was found to be significantly reduced only in the SR group. However, the AR outperformed the SR when it comes to improving superficial hydration, deep hydration, skin roughness, mean pore area, melanin heterogeneity, and crow's feet wrinkle depth. A significant increase in skin brightness from baseline was only recorded when using the AR while both routines significantly improved the nasolabial wrinkles.ConclusionThese findings advocate for using a relevant daily routine as it demonstrates the visible skin benefits over a short period, while driving the creation of habits for the prevention of aging signs.
The implementation of the Handicapping Labio‐Lingual Deviation index on access to orthodontic care
Authors: Caplin Jennifer , Rozgony Alexandria , Farhi Matan , Viana Grace C. , Al‐Grouz Malik , Belavsky Benjamin Z. 
Published: December 2019

AbstractObjectivesIn 2017, the state of Illinois changed the system by which they define severe malocclusion from the DentaQuest Orthodontic Criteria Index to the Handicapping Labio‐Lingual Deviation Index (HLD). The purpose of this study was to compare subjects who were submitted for coverage under either the DentaQuest Orthodontic Criteria Index or the HLD index to see if a difference exists in the number of subjects who received coverage and the type of malocclusions that were covered.MethodsAll subjects evaluated for orthodontic coverage by the Illinois Department of Human Services for treatment at the University of Illinois, College of Dentistry during the years 2016 and 2017 were included in this study. One hundred consecutively approved and 100 consecutively denied subjects from both 2016 and 2017 were selected for further analysis.ResultsThere was a statistically significant decrease in the overall rate of approval in 2017 compared to 2016. No difference was found in the approval rate of Class I, II, or III subjects, but there was a significant decrease in the approval rate of subjects with impacted teeth.ConclusionsThe implementation of the HLD index has significantly decreased access to orthodontic care for Medicaid patients in Illinois.
Access to Primary Care Physicians and Mortality in Washington State: Application of a 2‐Step Floating Catchment Area
Authors: Amiri Solmaz , Espenschied Jonathan R. , Roll John M. , Amram Ofer 
Published: December 2019

AbstractObjectiveTo measure access to primary care physicians (PCPs) using a 2‐step floating catchment area and explore the associations between access to PCPs and mortality related to all‐causes, cancers, and heart disease in Washington State.MethodsAn ecological study employing generalized linear regression models of access to PCPs and mortality rates in 4,761 block groups in Washington State in 2015. To measure access to PCPs, we used a 2‐step floating catchment area approach, taking into account area‐level population, supply of PCPs, and travel time between PCPs, as well as area‐level population with a distance decay function.ResultsA 1‐unit increase in PCP access score was associated with a reduction of 4.2 all‐cause deaths per 100,000 people controlling for socioeconomic characteristics. A 1‐unit increase in PCP access score was associated with a reduction of 2.7 cancer deaths and a reduction of 2.1 heart disease deaths per 100,000 people controlling for socioeconomic characteristics.ConclusionsBetter access to PCPs was associated with lower mortality from all‐causes, cancers, and heart disease. The 2‐step floating catchment area approach can help with the identification of PCP shortage areas, the development of rural residency programs, and the expansion of the physician workforce in Washington State and other regions.
Prevalence and Severity of Alcohol and Cannabis Use Across the Urban‐Rural Continuum in the Michigan National Guard
Authors: Coughlin Lara N. , Walton Maureen A. , McCormick Richard , Blow Frederic C. 
Published: December 2019

AbstractPurposeThe National Guard provides critical support both domestically and abroad with soldiers dispersed throughout America and spanning the urban‐rural continuum. To determine if location‐specific interventions may be needed, we compared the prevalence and severity of cannabis and alcohol use among National Guard members across localities.MethodsMichigan National Guard members were enrolled (N = 2,746) during drill weekends as part of a larger randomized behavioral trial. Cannabis (ASSIST; prevalence = 5%) and alcohol use (AUDIT; prevalence = 82%) were compared using hurdle regression models across locality status after adjusting for covariates.FindingsPrevalence of cannabis and alcohol use was predicted by locality (adjusted odds ratio [AOR] = 0.913, 95% CI: 0.838‐0.986, P = .029; AOR = 0.963, 95% CI: 0.929‐0.998, P = .038, respectively), with more use in urban localities. Neither severity of cannabis nor alcohol use was predicted by locality status.ConclusionsPrevalence of cannabis and alcohol use in the National Guard is differentially elevated across localities with higher prevalence in more central, densely populated areas. Findings may inform future work considering accessibility and utilization of prevention and treatment services for Guard members across the urban‐rural continuum.
Characteristics of the Sahara as a meteorite recovery surface
Authors: Aboulahris Maria , Chennaoui Aoudjehane Hasnaa , Rochette Pierre , Gattacceca Jérôme , Jull A. J. Timothy , Laridhi Ouazaa Nejia , Folco Luigi , Buhl Svend 
Published: December 2019

AbstractWe describe the geological, geomorphological, and paleoclimatic setting of the Sahara of North Africa in particular, focused on the main meteorite dense collection areas (DCA; Morocco, Algeria, Tunisia, and Libya). We report on the outcome of several meteorite recovery field expeditions in Morocco and Tunisia since 2008, by car and by foot, that applied systematic search methods. The number of meteorites collected is 41 ordinary chondrites and one brachinite. The statistics of unpaired ordinary chondrites indicates that H chondrites are more abundant (21) than L chondrites (12), while LL chondrites are rare (2). Our meteorite density estimates for Tunisia and Morocco are in the order of magnitude of 1 met km−2. An estimate of the total maximum number of meteorites that could be recovered from the Sahara is 780,000 meteorites. We selected 23 meteorites from Aridal, Bou Kra, Bir Zar, and Tieret DCAs for 14C dating. The results show a wide range of terrestrial ages from 0.4 to more than 40 kyr with a majority of meteorites showing ages between 0.4 and 20 kyr. The weathering degree of these meteorites is ranges from minor (W1) to strong (W4). The highest weathering grades result from repeated oscillations between high and low humidity in the Sahara. However, there appears to be no correlation between weathering grade and terrestrial age of meteorites.
The emotive effect of government branding on citizens' trust and its boundaries: Does the personal relevance of the policy issue matter?
Authors: Alon‐Barkat Saar 
Published: December 2019

AbstractRecent studies have demonstrated the potency of government branding to enhance citizens' trust in government organizations and policies. In addition, studies have pointed to the detrimental implications of this emotive effect, mainly its ability to compensate for organizations' poor functioning, and accordingly to elicit undue trust. In light of these concerns, this study explores the boundaries of governments' persuasion of citizens through branding and symbolic communications. Building on social psychology and marketing research, I hypothesize that citizens are less susceptible to persuasion by branding the more they perceive the policy issue as personally relevant. I test this expectation through a survey experiment, focused on air pollution policy in Israel, exploiting the natural variation in the perceived personal relevance between citizens residing in a polluted area in the country and others. The results indicate that even high levels of perceived personal relevance do not attenuate the effect of symbolic brand elements. This means that the boundaries of persuasion and manipulation through branding are wider than expected.
Evaluation of the contribution of teosinte to the improvement of agronomic, grain quality and yield traits in maize (Zea mays)
Authors: Wang Qingjun , Jiang Yi , Liao Zhengqiao , Xie Wubing , Zhang Xuemei , Lan Hai , Hu Erliang , Xu Jie , Feng Xuanjun , Wu Fengkai , Liu Yaxi , Lu Yanli 
Published: December 2019

AbstractTeosinte, an ancestor to modern maize, displays an excellent performance regarding resistance to stress, but its yield potential has rarely been reported. To evaluate the potential contribution of teosinte to maize improvement, two maize–teosinte backcrossed recombination inbred line (RIL) populations and their corresponding test‐cross hybrids were planted for trait assessment. In RN and ZP RIL populations, the average coefficients of variation of 31 agronomic traits were 9.14% (Range, 0.38%‒25.21%) and 6.85% (Range, 0.55%‒27.73%), respectively. The correlation coefficients of 13 common shared traits between RIL populations and test‐cross hybrid populations ranged from 0.10 to 0.60 and from 0.06 to 0.72, respectively. A total of 39 and 3 recombined inbred lines, and 29 and 47 test‐cross hybrids exhibited higher yields than their checks (RP125, Zheng58, CD189 and ZD958) with the BLUP data, respectively. Furthermore, four test‐cross hybrids including RN034/SCML1950, ZP068/Chang7‐2, ZP079/Chang7‐2 and ZP122/Chang7‐2 showed a more stable yield performance, with yield gains of +7.07%, +3.64%, +5.83% and +3.82% over checks, respectively. In conclusion, teosinte could serve as an alien germplasm for maize breeding.
Skin Cancer Awareness Among 1 271 Black Africans in South Africa
Authors: Wright Caradee Y. , Wallace Melissa , Mistri Preethi , Wernecke Bianca , Kapwata Thandi 
Published: December 2019

AbstractLittle is known about levels of awareness and perceptions of skin cancer among Africans living in Africa. This study assessed skin cancer awareness among 1271 deeply pigmented South Africans. Participants (n = 642 males vs n = 629 females) were aware of skin cancer (79%) with more females than males being aware of skin cancer (P = 0.02). Majority of all participants had never checked their skin for signs or symptoms of skin cancer (90%). Palms of hands and soles of feet were the least recognized anatomic sites for skin cancer development, despite these sites being the common sites for acral lentiginous melanoma in individuals with deeply pigmented skin. Results suggest a need for targeted skin cancer awareness among population groups with dark skin on identification, screening, and early detection, professional training for healthcare personnel and content on skin cancer in deeply pigmented skin in medical curricula.
Photoprotection by Workwear: Ultraviolet Protection Factors for Artificial Radiation from Welding Arcs
Authors: Bauer Stefan 
Published: December 2019

AbstractPhotoprotection by clothing is one of the most effective protective measures against solar ultraviolet radiation (UVR), and the related concept of UV protection factors (UPF) for fabrics has proven itself for decades. Although immense work has been carried out regarding factors influencing textile sun protection, the idea of UPFs for artificial UVR, if necessary with different action spectra, is payed little attention. In this work, a modified UPF equation is proposed utilizing welding arcs and the ICNIRP action spectrum. These welding UPFs (wUPF) were calculated for some workwear as a function of welding power, technique and welded material. No wUPF welding power dependence existed. By means of normalized standard emission spectra, that were further clustered with regard to welding technique, it was found that the wUPF depends exclusively on the fabric’s transmittance and the ICNIRP weighting function yielding a reduced wUPF formula. Finally, a comparison of solar and welding UPFs, based on either their full or reduced equations, is discussed.