bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Voltage Oxygen‐Redox‐Based Cathode for Rechargeable Sodium‐Ion Batteries
Authors: Konarov Aishuak , Kim Hee Jae , Jo Jae‐Hyeon , Voronina Natalia , Lee Yongseok , Bakenov Zhumabay , Kim Jongsoon , Myung Seung‐Taek 
Published: May 2020

AbstractRecently, anionic‐redox‐based materials have shown promising electrochemical performance as cathode materials for sodium‐ion batteries. However, one of the limiting factors in the development of oxygen‐redox‐based electrodes is their low operating voltage. In this study, the operating voltage of oxygen‐redox‐based electrodes is raised by incorporating nickel into P2‐type Na2/3[Zn0.3Mn0.7]O2 in such a way that the zinc is partially substituted by nickel. As designed, the resulting P2‐type Na2/3[(Ni0.5Zn0.5)0.3Mn0.7]O2 electrode exhibits an average operating voltage of 3.5 V and retains 95% of its initial capacity after 200 cycles in the voltage range of 2.3–4.6 V at 0.1C (26 mA g−1). Operando X‐ray diffraction analysis reveals the reversible phase transition: P2 to OP4 phase on charge and recovery to the P2 phase on discharge. Moreover, ex situ X‐ray absorption near edge structure and X‐ray photoelectron spectroscopy studies reveal that the capacity is generated by the combination of Ni2+/Ni4+ and O2−/O1− redox pairs, which is supported by first‐principles calculations. It is thought that this kind of high voltage redox species combined with oxygen redox could be an interesting approach to further increase energy density of cathode materials for not only sodium‐based rechargeable batteries, but other alkali‐ion battery systems.
Soil chemical properties after 12 years of tillage and crop rotation
Authors: Mikha Maysoon M. , Hergert Gary W. , Qiao Xin , Maharjan Bijesh 
Published: May 2020

AbstractCrop rotation in combination with tillage can improve productivity, enhance economical return, and reduce soil erosion. The objective of this study was to evaluate the impact of moldboard plow (MP), strip tillage (ST), no‐tillage (NT), and crop rotations on: (1) crop yield; (2) soil chemical properties; and (3) particulate organic matter (POM). The study was initiated in 2007 at the University of Nebraska‐Lincoln Panhandle Research and Extension Center near Scottsbluff, NE. Crops in rotation were corn (C; Zea mays L.) and dry bean (DB; Phaseolus vulgaris L.) organized in a 3‐yr rotation (C–DB–C) and a 4‐yr rotation with the addition of sugar beet (SB; Beta vulgaris L.) (C–DB–C–SB) such that each phase of the rotation was present each year. Soil samples collected from the surface 20 cm in the spring of 2019 were analyzed for POM and soil chemical properties. Crop yields were influenced by the previous crop, but not by tillage, except for sugar beet. The 2018 corn yield following dry bean exhibited the highest yield (15.6 Mg ha−1) compared with corn following corn or sugar beet. Soil chemical studied were not influenced by tillage or crop rotation. Corn in rotation enhanced soil organic matter (SOM) by 22% and soil organic carbon (SOC) by 28% in corn in the 3‐yr rotation compared with corn in the 4‐yr rotation. Surface soil POM was 32% higher with NT than MP and 17% higher in ST than MP. Alternative management strategies need to be implemented to maintain land sustainability in rotation with sugar beet and dry bean.
A mass and energy balance stage model for cyclic distillation
Authors: Rasmussen Jess Bjørn , Mansouri Seyed Soheil , Zhang Xiangping , Abildskov Jens , Huusom Jakob Kjøbsted 
Published: May 2020

AbstractCyclic distillation is an emerging process intensification technology, which can improve separation efficiency compared to conventional distillation. As most current models only account for the mass transfer, there is a lack of a stage model for cyclic distillation processes, which includes considerations of both mass and energy transfer. Such a model is presented in this article, and using this model, selected case studies, describing binary and multiple component systems with both ideal and nonideal liquid phases, are investigated. The presented stage model allows for the modeling of both mass and energy transfer for a cyclic distillation process and allows for multiple feed locations, as well as side draws. With the energy balances included, the dynamic vapor flow rate can be described. This was shown to have a significant effect on the separation, especially for cases where the change in the vapor flow over the column height was high.
Hodgkin lymphoma: A 2020 update on diagnosis, risk‐stratification, and management
Authors: Ansell Stephen M. 
Published: May 2020

AbstractDisease overviewHodgkin lymphoma (HL) is an uncommon B‐cell lymphoid malignancy affecting 8480 new patients annually and representing approximately 10% of all lymphomas in the United States.DiagnosisHodgkin lymphoma is composed of two distinct disease entities: classical HL and nodular lymphocyte predominant HL. Nodular sclerosis, mixed cellularity, lymphocyte depletion, and lymphocyte‐rich HL are subgroups of classical HL.Risk stratificationAn accurate assessment of the stage of disease in patients with HL is critical for the selection of the appropriate therapy. Prognostic models that identify patients at low or high risk for recurrence, as well as the response to therapy as determined by positron emission tomography (PET) scan, are used to optimize therapy.Risk‐adapted therapyInitial therapy for HL patients is based on the histology of the disease, the anatomical stage and the presence of poor prognostic features. Patients with early stage disease are typically treated with combined modality strategies utilizing abbreviated courses of combination chemotherapy, followed by involved‐field radiation therapy. Patients with advanced stage disease receive a longer course of chemotherapy, often without radiation therapy. However, newer agents including brentuximab vedotin and anti‐PD‐1 antibodies are now being incorporated into frontline therapy.Management of relapsed/refractory diseaseHigh‐dose chemotherapy (HDCT) followed by an autologous stem cell transplant (ASCT) is the standard of care for most patients who relapse following initial therapy. For patients who fail HDCT with ASCT, brentuximab vedotin, PD‐1 blockade, non‐myeloablative allogeneic transplant or participation in a clinical trial should be considered.
Assessing recovery rate methods: A review and application for human skeletal assemblages
Authors: Palmiotto Andrea , LeGarde Carrie B. , Brown Carrie A. 
Published: May 2020

AbstractObjectivesRecovery rates reflect the amount of recovered skeletal materials based on expectations about the total number of elements or individuals that should be present in an assemblage. It is an underlying concept that reflects analytical potential, wherein high recovery rates typically indicate high analytical capabilities. However, numerous methods are available to calculate different types of recovery rates, and each method addresses various types of research questions and utilizes different variables. Therefore, recovery rates cannot be applied and compared directly, and the appropriate recovery rate for any given research question must be considered thoughtfully.Materials and MethodsSeveral methods of determining individual and element recovery rates are applied to the USS Oklahoma commingled human remains assemblage and discussed with regard to their utility.ResultsDepending on which method is used, recovery rates range from 91 to 102% for the recovery of individuals and 0.02 to 91% for the recovery of elements within this assemblage.DiscussionThese results emphasize the need to carefully consider which recovery rate is most appropriate based on associated research questions and project contexts. We introduce the idea of the analytical recovery rate, a flexible concept to determine the potential assessment of biological profile parameters once individuation of commingled remains has occurred, wherein elements are selected based on the needs of the project as well as element preservation.
Proton pump inhibitors act with unprecedented potencies as inhibitors of the acetylcholine biosynthesizing enzyme—A plausible missing link for their association with incidence of dementia
Authors: Kumar Rajnish , Kumar Amit , Nordberg Agneta , Långström Bengt , Darreh‐Shori Taher 
Published: May 2020

AbstractIntroductionSeveral pharmacoepidemiological studies indicate that proton pump inhibitors (PPIs) significantly increase the risk of dementia. Yet, the underlying mechanism is not known. Here, we report the discovery of an unprecedented mode of action of PPIs that explains how PPIs may increase the risk of dementia.MethodsAdvanced in silico docking analyses and detailed enzymological assessments were performed on PPIs against the core‐cholinergic enzyme, choline‐acetyltransferase (ChAT), responsible for biosynthesis of acetylcholine (ACh).ResultsThis report shows compelling evidence that PPIs act as inhibitors of ChAT, with high selectivity and unprecedented potencies that lie far below their in vivo plasma and brain concentrations.DiscussionGiven that accumulating evidence points at cholinergic dysfunction as a driving force of major dementia disorders, our findings mechanistically explain how prolonged use of PPIs may increase incidence of dementia. This call for restrictions for prolonged use of PPIs in elderly, and in patients with dementia or amyotrophic lateral sclerosis.
Understanding the Band Engineering in Mg2Si‐Based Systems from Wannier‐Orbital Analysis
Authors: Tan Xiaojian , Yin Yinong , Hu Haoyang , Xiao Yukun , Guo Zhe , Zhang Qiang , Wang Hongxiang , Liu Guo‐Qiang , Jiang Jun 
Published: May 2020

AbstractThe Mg2SiSnx solid solution is one of the most representative examples of band engineering, in which the thermoelectric performance is significantly improved by the conduction band convergence. The mechanism behind it is simply explained by the chemical differences between Si and Sn. Here a systematically theoretical study is reported based on Wannier function analysis. It is revealed that the band convergence in Mg2SiSnx is actually driven by the variation of lattice constant, since the heavy and light conduction valleys have different dependence on the bonding length. Alternatively, the band engineering can also be achieved by introducing cation dopants to tune the relative strength of the two chemical bonds directly. In MgSrxSi, a similar band convergence to Mg2SiSnx is predicted by the band structure calculations. This work provides an insightful understanding of the band convergence in Mg2Si‐based materials, and it enables a more efficient and plentiful design for experimental studies.
Accelerated and Robust Generation of W State by Parametric Amplification and Inverse Hamiltonian Engineering
Authors: Liu Shuai , Ran Du , Kang Yi‐Hao , Shi Zhi‐Cheng , Song Jie , Xia Yan 
Published: May 2020

AbstractA scheme to realize the accelerated and robust generation of W state in a cavity quantum electrodynamics (QED) system by combining parametric amplification (PA) with inverse Hamiltonian engineering (IHE) is proposed. The atom‐cavity coupling strength can be exponentially enhanced via parametrically squeezing the cavity mode, which facilitates the generation of W state. Moreover, the evolution of the system can be optimized with suppressing the populations of the intermediate states. Numerical simulations show that the scheme is fast and high‐fidelity, immune to systematic parameter deviations, robust against spontaneous emission of atoms, and decay of cavities. Therefore, this scheme may provide some useful applications in entanglement generation.
Online privacy concerns and privacy protection strategies among older adults in East York, Canada
Authors: Quan‐Haase Anabel , Ho Dennis 
Published: May 2020

AbstractAs news headlines report on high‐profile online privacy breaches and the potential negative consequences for users, users are becoming concerned about their privacy. While much research has focused on the concerns of younger generations, few studies have investigated older adults, specifically those aged 65+ years. This study analyzes in‐depth interviews with 40 older adults living in East York, Toronto, Canada, to investigate their online privacy concerns and the strategies they use to mitigate these concerns. We find that East York older adults are mostly concerned about security privacy concerns followed by institutional privacy concerns and only minimally concerned about social privacy. The greatest concerns included information misuse by unknown others and unauthorized access to their personal information. We found that, for some older adults, their high privacy concerns precluded them from taking full advantage of the potential benefits of digital media. East York older adults varied considerably in their use of privacy protection strategies; some older adults used no strategies, while others were eager to protect their privacy using all strategies at their disposal.
High‐throughput profiling reveals perturbation of endoplasmic reticulum stress‐related genes in atherosclerosis induced by high‐cholesterol diet and the protective role of vitamin E
Authors: Bozaykut Perinur , Ekren Ruchan , Sezerman Osman Ugur , Gladyshev Vadim N. , Ozer Nesrin Kartal 
Published: May 2020

AbstractFormation of atherosclerotic plaques, called atherogenesis, is a complex process affected by genetic and environmental factors. It was proposed that endoplasmic reticulum (ER) stress is an important factor in the pathogenesis of atherosclerosis and that vitamin E affects atherosclerotic plaque formation via its antioxidant properties. Here, we investigated ER stress‐related molecular mechanisms in high‐cholesterol diet (HCD, 2%)‐induced atherosclerosis model and the role of vitamin E supplementation in it, beyond its antioxidant properties. The consequences of HCD and vitamin E supplementation were examined by determining protein levels of ER stress markers in aortic tissues. As vitamin E supplementation acts on several unfolded protein response (UPR) factors, it decreased ER stress induced by HCD. To elucidate the associated pathways, gene expression profiling was performed, revealing differentially expressed genes enriched in ER stress‐related pathways such as the proteasome and the apoptosis pathways. We further assessed the proteasomal activity impaired by HCD in the aorta and showed that vitamin E reversed it to that of control animals. Overall, the study characterized the effects of HCD and vitamin E on ER stress‐related gene expression, revealing the role of proteolytic systems during atherogenesis.
Transcription Factor ArcA is a Flux Sensor for the Oxygen Consumption Rate inEscherichia coli
Authors: Nochino Naoya , Toya Yoshihiro , Shimizu Hiroshi 
Published: May 2020

AbstractOxygen supply is one of the major factors determining the metabolic state in microorganisms, and it affects the productivity of various compounds during bioproduction. InEscherichia coli(E. coli), the expression levels of numerous metabolic genes are regulated by transcription factors in response to changes in environmental oxygen conditions. Even at a same dissolved oxygen concentration, the amount of available oxygen changes depending on the oxygen transfer coefficient. However, it is not known whetherE. coliis able to sense differences in the oxygen consumption rate. Therefore, the present study, is focused on the role of the transcription factor ArcA in the oxygen response ofE. coliand investigated the relationship between ArcA activity and the oxygen consumption rate. To evaluate the activity of ArcA, a sensor plasmid expressing fluorescent protein under the control of theicdpromoter, which is regulated by ArcA, is designed.E. colicontaining the sensor plasmid is grown in continuous cultures with different oxygen supplies under different dilution rates. Although there is no correlation between ArcA activity and dissolved oxygen concentration, a strong negative correlation between ArcA activity and the specific oxygen consumption rate (R2> 0.93) is observed.
Building responses to sustainable development challenges: A multistakeholder collaboration framework and application to climate change
Authors: Elia Gianluca , Margherita Alessandro , Petti Claudio 
Published: May 2020

AbstractThe affirmation of open innovation and collaborative systems is enabling unprecedented opportunities to create business value while facilitating multistakeholder conversation on sustainability issues. In particular, platform‐based models are emerging as organization archetypes able to facilitate cooperative dynamics among industrial actors, policy makers, academicians, scientists, and citizens. In this article, we use interdisciplinary business management and collaborative innovation literature to build the conceptual framework of a multisided platform as a collaboration environment gathering actors willing to define responses to sustainable development challenges. We present five dimensions or “genes,” that is, the focus and strategic intent or orientation of the platform (what), the participating sides, actors and groups (who), the actions, flows and coordination mechanisms (how), and the value drivers, benefits and externalities (why), and the rules regulating the affiliation and interaction processes (governance). We also present and discuss 30 subtopics or management items that are associated with the five dimensions defined. We then apply the conceptual model to analyze a case in the climate change endeavor and to show how competitive and cooperative dynamics can be virtuously integrated to provide individual‐ and company‐driven responses to a timely socioenvironmental issue. The article provides a new perspective on collaboration to enhance social development, and it offers theoretical and practitioner insights for a broad interdisciplinary audience including scholars, practitioners, business, and platform managers.
Organizational characteristics explaining participation in sustainable business models in the sharing economy: Evidence from the fashion industry using conjoint analysis
Authors: Cocquyt Astrid , Crucke Saskia , Slabbinck Hendrik 
Published: May 2020

AbstractEnvironmental and social challenges require new sustainable business models, like sharing platforms. However, sharing platforms differ widely in their contribution to a more sustainable society. Whereas idealistic sharing platforms have dominant social goals, other sharing platforms are, or became, commercial. We explore the attractiveness of the typical organizational characteristics of idealistic sharing platforms in the fashion industry context, an industry with negative environmental and social impacts. Based on a literature review and exploratory focus groups, we conduct an online survey using conjoint analysis, completed by 1,512 respondents. Our results reveal that potential users prefer clothes sharing platforms to be small, to not partner with large clothing retailers, to have the possibility to participate in decision‐making, but to not require shareholding.
Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease
Authors: Meehan Katie , Leslie Connull , Lucas Michaela , Jacques Angela , Mirzai Bob , Lim James , Bulsara Max , Khan Yasir , Wong Nicholas C. , Solomon Benjamin , Sader Chady , Friedland Peter , Mir Arnau Gisela , Semple Timothy , Lim Annette M. 
Published: May 2020

AbstractWe investigated whether a unique immune response was instigated with the development of oral tongue squamous cell carcinomas (OTSCC), with/without nodal involvement, with/without recurrent metastatic disease, or within tumor involved nodes. One hundred and ten formalin‐fixed paraffin‐embedded samples were collected from a retrospective cohort of 67 OTSCC patients and 10 non‐cancerous tongue samples. Targets including CD4, CD8, FOXP3, PD‐L1, and PD‐1 were analyzed by immunohistochemistry. The Nanostring PanCancer Immune Profiling Panel was used for gene expression profiling. Data were externally validated in the The Cancer Genome Atlas (TCGA) head and neck (HNSCC), melanoma and lung squamous cell carcinoma (LSCC) cohorts. A 24‐immune gene signature was identified that discriminated more aggressive OTSCC cases, and although not prognostic in HNSCC was associated with survival in other TCGA cohorts (improved survival for melanoma, P < .001 and worse survival for LSCC, P = .038). OTSCC exhibited concordant gene and immunohistochemical (IHC) features characterized by a TH‐2 biased, proinflammatory profile with upregulated B cell and neutrophil gene activity and increased CD4, FOXP3, and PD‐L1 expression (P < .001 for all by IHC). Compared to less advanced disease, nodal involvement and recurrent OTSCC did not induce a different immune response although recurrent disease was characterized by significantly higher PD‐L1 expression (P = .004 by SP263, P = .013 by 22C3, P = .004 for gene expression). Identification of a gene signature associated with different prognostic effects in other cancers highlights common pathways of immune dysregulation that are impacted by the tumor origin. The significant immunosuppressive signaling in OTSCC indicates primary failure of immune system to control carcinogenesis emphasizing the need for early, combination therapeutic approaches.
Amelogenesis imperfecta with Class III malocclusion, reduced crown size and decreased OVD: A multi‐disciplinary management and a 5‐year follow‐up
Authors: Labidi Amel , Bekri Sana , Mabrouk Yosra , Ben Mustapha Jouda , Omezzine Monia , Ghoul‐Mazgar Sonia , Mansour Lamia 
Published: May 2020

AbstractThis clinical report describes the oral rehabilitation of a 22‐year‐old‐man diagnosed with a variant of hypoplastic amelogenesis imperfecta. The treatment approach was multi‐disciplinary, and it included the surgical procedure of Lefort I osteotomy, surgical crown lengthening, and metal‐ceramic‐fixed dental prostheses. The patient was satisfied with the esthetic and functional outcome.
Protection of Ruthenium Olefin Metathesis Catalysts by Encapsulation in a Self‐assembled Resorcinarene Capsule
Authors: Jongkind Lukas J. , Rahimi Maryam , Poole David , Ton Stephanie J. , Fogg Deryn E. , Reek Joost N. H. 
Published: May 2020

AbstractCatalyst encapsulation is examined as a means of increasing the productivity of olefin metathesis catalysts. Commercially available, cationic ruthenium metathesis catalysts were incorporated into a supramolecular resorcin[4]arene capsule. Encapsulation increased catalyst stability in water‐saturated toluene, delivering higher metathesis yields than the parent, non‐encapsulated Hoveyda catalyst in the same reaction medium.
Testing the vibrational exciton and the local mode models on the instructive cases of dicarvone, dipinocarvone, and dimenthol vibrational circular dichroism spectra
Authors: Mazzeo Giuseppe , Santoro Ernesto , Abbate Sergio , Zonta Cristiano , Fabris Fabrizio , Longhi Giovanna 
Published: May 2020

AbstractThe vibrational circular dichroism (VCD) spectra of dicarvone (1), dipinocarvone (2), and dimenthol (3) have been recorded in the range 900–3200 cm−1, encompassing the mid‐infrared (mid‐IR), the CO stretching, and the CH‐stretching regions. For compound 3 also, the fundamental and the first overtone OH stretching regions have been investigated by IR/NIR absorption and VCD. Density functional theory (DFT) calculations allow one to interpret the IR and VCD spectra and to confirm the configuration/conformational studies previously conducted by X‐ray diffraction. The most intense VCD signals are associated with the vibrational normal modes involving symmetry‐related groups close to the CC bond connecting covalently the two molecular units. The vibrational exciton (VCDEC) model is fruitfully tested on the VCD data of compounds 1 and 2 for the spectroscopic regions at ~1700 cm−1, and the local mode model is tested on compound 3 at ~3500 and ~6500 cm−1. For compounds 1 and 2 also, ECD spectra are reported, and the exciton mechanism is tested also there, and connections to the VCDEC model are examined.