bluuebunny/crossref_metadata_2025_split huggingface dataset:
Allocation of intensive care resources during an infectious disease outbreak: a rapid review to inform practice
Authors: Fiest Kirsten M. , Krewulak Karla D. , Plotnikoff Kara M. , Kemp Laryssa G. , Parhar Ken Kuljit S. , Niven Daniel J. , Kortbeek John B. , Stelfox Henry T. , Parsons Leigh Jeanna 
Published: December 2020

AbstractBackgroundThe COVID-19 pandemic has placed sustained demand on health systems globally, and the capacity to provide critical care has been overwhelmed in some jurisdictions. It is unknown which triage criteria for allocation of resources perform best to inform health system decision-making. We sought to summarize and describe existing triage tools and ethical frameworks to aid healthcare decision-making during infectious disease outbreaks.MethodsWe conducted a rapid review of triage criteria and ethical frameworks for the allocation of critical care resources during epidemics and pandemics. We searched Medline, EMBASE, and SCOPUS from inception to November 3, 2020. Full-text screening and data abstraction were conducted independently and in duplicate by three reviewers. Articles were included if they were primary research, an adult critical care setting, and the framework described was related to an infectious disease outbreak. We summarized each triage tool and ethical guidelines or framework including their elements and operating characteristics using descriptive statistics. We assessed the quality of each article with applicable checklists tailored to each study design.ResultsFrom 11,539 unique citations, 697 full-text articles were reviewed and 83 articles were included. Fifty-nine described critical care triage protocols and 25 described ethical frameworks. Of these, four articles described both a protocol and ethical framework. Sixty articles described 52 unique triage criteria (29 algorithm-based, 23 point-based). Few algorithmic- or point-based triage protocols were good predictors of mortality with AUCs ranging from 0.51 (PMEWS) to 0.85 (admitting SOFA > 11). Most published triage protocols included the substantive values of duty to provide care, equity, stewardship and trust, and the procedural value of reason.ConclusionsThis review summarizes available triage protocols and ethical guidelines to provide decision-makers with data to help select and tailor triage tools. Given the uncertainty about how the COVID-19 pandemic will progress and any future pandemics, jurisdictions should prepare by selecting and adapting a triage tool that works best for their circumstances.
Social Internet of Things: vision, challenges, and trends
Authors: Malekshahi Rad Mozhgan , Rahmani Amir Masoud , Sahafi Amir , Nasih Qader Nooruldeen 
Published: December 2020

Abstract
IoT describes a new world of billions of objects that intelligently communicate and interact with each other. One of the important areas in this field is a new paradigm-Social Internet of Things (SIoT), a new concept of combining social networks with IoT. SIoT is an imitation of social networks between humans and objects. Objects like humans are considered intelligent and social. They create their social network to achieve their common goals, such as improving functionality, performance, and efficiency and satisfying their required services. Our article’s primary purpose is to present a comprehensive review article from the SIoT system to analyze and evaluate the recent works done in this area. Therefore, our study concentrated on the main components of the SIoT (Architecture, Relation Management, Trust Management, web services, and information), features, parameters, and challenges. To gather enough information for better analysis, we have reviewed the articles published between 2011 and December 2019. The strengths and weaknesses of each article are examined, and effective evaluation parameters, approaches, and the most used simulation tools in this field are discussed. For this purpose, we provide a scientific taxonomy for the final SIoT structure based on the academic contributions we have studied. Ultimately we observed that the evaluation parameters are different in each element of the SIoT ecosystem, for example for Relation Management, scalability 29% and navigability 22% are the most concentrated metrics, in Trust Management, accuracy 25%, and resiliency 25% is more important, in the web service process, time 23% and scalability 16% are the most mentioned and finally in information processing, throughput and time 25% are the most investigated factor. Also, Java-based tools like Eclipse has the most percentage in simulation tools in reviewed literature with 28%, and SWIM has 13% of usage for simulation.
Are benzodiazepines effective in treating catatonia?
Authors: Carthy Elliott 
Published: December 2020

SUMMARYEstablishing an evidence base for the clinical management of catatonia is made difficult by the heterogeneous nature of the condition and the limited understanding of its pathophysiology. Benzodiazepines are a mainstay of treatment. The Cochrane review discussed identified only one eligible study (17 participants with catatonia who received either lorazepam or oxazepam), which found no difference on the single outcome measure (a 50% improvement on a visual analogue scale). This commentary discusses the findings in more detail, and considers what constitutes high-quality evidence for the acute treatment of catatonia, why there is such a paucity of randomised controlled trials (RCTs) on the topic and whether RCTs are both feasible and appropriate for the condition.
Glucose Tolerance Stages in Cystic Fibrosis Are Identified by a Unique Pattern of Defects of Beta-Cell Function
Authors: Piona Claudia , Volpi Sonia , Zusi Chiara , Mozzillo Enza , Tosco Antonella , Franzese Adriana , Raia Valeria , Boselli Maria Linda , Trombetta Maddalena , Cipolli Marco , Bonadonna Riccardo C , Maffeis Claudio 
Published: December 2020

Abstract

Objective
We aimed to assess the order of severity of the defects of 3 direct determinants of glucose regulation—beta-cell function, insulin clearance, and insulin sensitivity—in patients with cystic fibrosis (CF), categorized according their glucose tolerance status, including early elevation of mid-level oral glucose tolerance test (OGTT) glucose values (&gt;140 and &lt;200 mg/dL), referred to as AGT140.

Methods
A total of 232 CF patients aged 10 to 25 years underwent OGTT. Beta-cell function and insulin clearance were estimated by OGTT mathematical modeling and OGTT-derived biomarkers of insulin secretion and sensitivity were calculated. The association between glucometabolic variables and 5 glucose tolerance stages (normal glucose tolerance [NGT], AGT140, indeterminate glucose tolerance [INDET], impaired glucose tolerance [IGT], cystic fibrosis–related diabetes CFRD]) was assessed with a general linear model.

Results
Beta-cell function and insulin sensitivity progressively worsened across glucose tolerance stages (P &lt; 0.001), with AGT140 patients significantly differing from NGT (all P &lt; 0.01). AGT140 and INDET showed a degree of beta-cell dysfunction similar to IGT and CFRD, respectively (all P &lt; 0.01). Insulin clearance was not significantly associated with glucose tolerance stages (P = 0.162). Each stage of glucose tolerance was uniquely identified by a specific combination of defects of the direct determinants of glucose regulation.

Conclusions
In CF patients, each of the 5 glucose tolerance stages shows a unique pattern of defects of the direct determinants of glucose regulation, with AGT140 patients significantly differing from NGT and being similar to IGT. These findings suggest that AGT140 should be recognized as a distinct glucose tolerance stage and that reconsideration of the grade of glucometabolic deterioration across glucose tolerance stages in CF is warranted.
Incidence of acute pulmonary embolism among patients hospitalized with COVID-19: a systematic review and meta-analysis
Authors: Munner Mohamed S. , Ritchie Charles A. , Elkhidir Ibrahim H. , Mohammadat Doaa T. , Ahmed Hussein J. , Altayeb Khalid A. , Yassin Rawan Z. , Hassan Riyan M. , Hamad Saada A. , Nimir Mohammed , Hamid Osman S. , Johnson Margaret M. , Narula Tathagat , Erben Young , Tawk Rabih G. , Miller David A. , Gupta Vivek , Devcic Zlatko , Freeman William D. , Toskich Beau B. 
Published: December 2020

Background: Coronavirus disease 2019 (COVID-19) is a global pandemic, which is associated with venous thromboembolism and pulmonary embolism (PE). This study aimed to estimate the pooled incidence of PE among patients hospitalized with COVID-19 within the published literature. Methods: This systematic review and meta-analysis was performed according to PRISMA guidelines. An electronic search using MEDLINE /PubMed, ScienceDirect, Cochrane, and OpenGray databases was conducted May 19th, 2020. Search terms included "COVID 19", "SARS-CoV-2”, "coronavirus disease 2019", "2019-nCoV", "Wuhan coronavirus", “Pulmonary embolism”, "pulmonary thromboembolism", “Pulmonary embol*”, “pulmonary thrombo*” and “PE”. Eligible studies included sufficient data to calculate the incidence of PE diagnosed during hospitalization in patients with COVID-19. Case reports were excluded. Quality was assessed using the Newcastle-Ottawa scale (observational cohort and case-control), AXIS tool (cross-sectional), and quality assessment tool (case series). Demographics and PE incidence data were extracted from the included studies and analyzed with R language. The pooled incidence of PE in patients hospitalized with COVID-19 was calculated. Results: The database search identified 128 records. Ten observational studies were eligible and were included in the meta-analysis with a total of 1722 patients (mean age= 63.36). The pooled PE incidence in patients hospitalized with COVID-19 was 17% (95% CI: 0.1-0.26). There was a high degree of study heterogeneity (I2 = 94%, p<0.01). Conclusion: The pooled PE incidence in patients hospitalized with COVID-19 is 17%. This increased incidence is greater than that previously reported in the general population of non-COVID-19. Attention and further investigation of this risk is warranted.
The efficacy of acupuncture as a complementary treatment for pain and anxiety after breast cancer surgery: Study protocol for a pragmatic randomized control trial
Authors: López de San Román-Fernández Cristina , Fernández-Jané Carles , Cusidó Maite , Costa-Tutusaus Lluís 
Published: December 2020

Background: Breast cancer is one of the most prevalent cancers worldwide. Fortunately, survival has improved in recent years thanks to its early detection and curative treatments such as mastectomy. However, this medical procedure is associated with a range of unwanted effects such as postoperative pain and anxiety. Some studies have reported that acupuncture could be an effective treatment to control these types of symptoms, although only few studies have been conducted on women undergoing mastectomy. Methods: This is a pragmatic randomized controlled trial with blind assessors. The study will be conducted in the Breast Unit of Hospital Universitario Sagrado Corazon of Barcelona (Spain). A sample of 40 women will be recruited and randomized to receive acupuncture treatment in addition to standard care procedures, or standard care procedures alone. The main outcome, pain, will be assessed after the surgical intervention and 4, 10 and 30 days later using the numerical rating scale. Secondary outcomes include anxiety, use of analgesics, nausea, adverse effects, and surgical complications. Discussion: Acupuncture is a low-cost non-pharmacological strategy. This study will help to clarify its possible role in controlling post-mastectomy adverse effects. Trial registration: ClinicalTrials.gov NCT04608175 29/10/2020
Adverse drug reactions associated with the use of biological agents
Authors: Machado-Alba Jorge Enrique , Jiménez-Morales Anyi Liliana , Moran-Yela Yulieth Carolina , Parrado-Fajardo Ilsa Yadira , Valladales-Restrepo Luis Fernando 
Published: December 2020

Introduction
Biological drugs open new possibilities to treat diseases for which drug therapy is limited, but they may be associated with adverse drug reactions (ADRs).

Objective
To identify the ADRs associated with the use of biological drugs in Colombia.

Methods
This was a retrospective study of ADR reports from 2014 to 2019, contained in the database of Audifarma SA pharmacovigilance program. The ADRs, groups of associated drugs, and affected organs were classified.

Results
In total, 5,415 reports of ADRs associated with biological drugs were identified in 78 Colombian cities. A total of 76.1% of the cases corresponded to women. The majority were classified as type A (55.0%) and B (28.9%), and 16.7% were serious cases. The respiratory tract was the most affected organ system (16.8%), followed by the skin and appendages (15.6%). Antineoplastic and immunomodulatory drugs accounted for 70.6% of the reports, and the drugs related to the greatest number of ADRs were adalimumab (12.2%) and etanercept (11.6%).

Conclusions
The reporting of ADRs has increased in recent years and these reactions are mostly classified as tyoe A or B, categorized as serious in almost one-fifth of the reported cases and associated mainly with immunomodulators and antineoplastic agents. This type of study can support decision makers in ways that benefit patient safety and interaction with health systems.
A phenomenological study on the lived experiences of families of ICU patients, Addis Ababa, Ethiopia
Authors: Kehali Habtamu , Berhane Yemane , Gize Addisu 
Published: December 2020

BackgroundFamily-centered care of ICU patients is increasingly recommended as it is believed to have effect on family members’ psychosocial status and patient outcomes. Defining the nature and extent of families’ involvement in a given health care environment for different stakeholders is a challenge. Understanding the lived experiences of families of ICU patients would help strategize on how to better engage family members for improved ICU care processes and outcomes.ObjectivesThe aim of this study is to explore the lived experiences of families of patients in the ICUs of hospitals in Addis Ababa, Ethiopia.MethodsThe study adopted a qualitative approach and a phenomenological research design. In-depth interviews were conducted with twelve (12) family members who were purposively sampled from two government hospitals and four private hospitals. Thematic approach with the application of hermeneutic circle of interpretation was applied to understand the meanings of their experiences.ResultsThe study revealed the following major themes: financial burden, challenge in decision making, shattered family integrity and expectations, information and communication gap between family members and health professionals, lack of confidence in the service delivery of hospitals, social pressure against patient families, and families being immersed in an unfriendly environment. Though they do not explicitly mention it to the health care tram, further interpretation of the main themes elucidated that family’s need the intensive care process be cut shorter irrespective of the outcome of the patient condition.ConclusionThe study gave an insight on the multiple and interrelated challenges faced by families of ICU patients admitted in the hospitals of Addis Ababa. Further contextualized interpretation of their experiences revealed that families were somehow in a state of despair and they implicitly need the ICU care for their family member be ended irrespective of the potential clinical consequences on the patient. The philosophy of family-centered care be advocated in hospitals. The study result affirms the need to include family members during nursing assessment of patients in ICUs and also offers the basis for guidelines development on informational support to the families of the patients hospitalized in ICUs.
Health-related quality of life of the Vietnamese during the COVID-19 pandemic
Authors: Vu Mai Quynh , Tran Thao Thi Phuong , Hoang Thao Anh , Khuong Long Quynh , Hoang Minh Van 
Published: December 2020

Background
Vietnam applied strict quarantine measures to mitigate the rapid transmission of the SARS-COV-2 virus. Central questions were how the COVID-19 pandemic affected health-related quality of life (HRQOL) of the Vietnamese general population, and whether there is any difference in HRQOL among people under different quarantine conditions.

Methods
This cross-sectional study was conducted during 1 April– 30 May 2020 when the COVID-19 pandemic was at its peak in Vietnam. Data was collected via an online survey using Google survey tool. A convenient sampling approach was employed, with participants being sorted into three groups: people who were in government quarantine facilities; people who were under self-isolation at their own place; and the general population who did not need enforced quarantine. The Vietnamese EQ-5D-5L instrument was used to measure HRQOL. Differences in HRQOL among people of isolation groups and their socio-demographic characteristics were statistically tested.

Results
A final sample was made of 406 people, including 10 persons from government quarantine facilities, 57 persons under self-isolation at private places, and the rest were the general population. The mean EQ-VAS was reported the highest at 90.5 (SD: 7.98) among people in government quarantine facilities, followed by 88.54 (SD: 12.24) among general population and 86.54 (SD 13.69) among people in self-isolation group. The EQ-5D-5L value was reported the highest among general population at 0.95 (SD: 0.07), followed by 0.94 (SD: 0.12) among people in government quarantine facilities, and 0.93 (SD: 0.13) among people who did self-isolation. Overall, most people, at any level, reported having problems with anxiety and/or depression in all groups.

Conclusion
While there have been some worries and debates on implementing strict quarantine measures can hinder people’s quality of life, Vietnam showed an opposite tendency in people’s HRQOL even under the highest level of enforcement in the prevention and control of COVID-19.
Between Legacy and Agency: Italo-Eritreans Raised in Orphanages and Their Access to Italian Citizenship
Authors: Fusari Valentina 
Published: December 2020

Abstract
In Eritrea, Italian colonialism introduced and regulated the opportunity for mixed-race individuals with Italian ancestry to obtain Italian citizenship. This opportunity was modified over time depending on changes in Italian and Eritrean citizenship laws. Moreover, laws and socialization shaped Italo-Eritreans as a minority and a “different” group that reproduced itself even after colonialism. Over time, the number of Italo-Eritreans varied as did their sense of belonging to a real or imagined community. The case of mixed-race children abandoned during Italian colonialism provides an insight into the importance of social institutions in building legal and social identities through socialization. Using an interdisciplinary, qualitative-quantitative approach, I focus on the convergence between the processes of inclusion within legal (citizenship) and social (identity) categories, as well as on the agency of Italo-Eritreans raised in orphanages in transforming a stigma into a resource to gain the Italian citizenship.
Soldier-Citizen Training: The Early Boy Scout Movement in Ethiopia (1920s–1950s)
Authors: Bromber Katrin 
Published: December 2020

Abstract
Under the motto Zǝgǝğu! (Be prepared!), Ethiopian Boy Scouts attempt to become part of an imperial, national, and global community. Since its formation a century ago, the movement changed its character and served different ends. By looking at the foundational period between the 1920s and 1950s, this article investigates to what extent the Ethiopian movement provides a lens through which we can examine the notion of citizenship. Because scouting has a militarized connotation, this article probes the possibility of applying the concept of the “soldier-citizen” as a temporary, yet specific, form of citizenship. The article argues that during the 1920s and 1930s the Ethiopian movement had a clear militaristic aim. It functioned to train cadets, not serving citizens. In the postliberation context, the movement relied on ideas about taming and disciplining young men by channeling their energy towards building a modern nation. Through its inclusion in the newly established Department of Physical Education within the Ministry of Education and Fine Arts (MoE), scouting became an integral part of the educational system. The article argues that it provided a specific kind of citizenship training at a time when other volunteer organizations (e.g., the Young Men’s Christian Association [YMCA]) were also developing the notion of citizen into an aspirational category.
Implementación de la Agenda 2030 a través de un proyecto de investigación-acción aplicando la metodología flipped classroom
Authors: Calvo Centeno María Esperanza , Espín Ocampo Julieta , Peset González María José , Ruiz González Moisés 
Published: December 2020

El propósito del proyecto de investigación-acción, en el que se enmarca la actividad objeto del presente estudio, es incorporar en las áreas de conocimiento de los futuros egresados, el mensaje contenido en la Agenda 2030 de Naciones Unidas con el objetivo de que lo interioricen y, así, favorecer que puedan incorporarlo a su actividad profesional o laboral.
La metodología utilizada para llevar a cabo la actividad es flipped classroom o aula invertida, por considerar que es la metodología más adecuada para que el alumno profundice en los problemas a los que se enfrenta el planeta, sea consciente de los mismos y, en consecuencia, adquiera las competencias necesarias que le permitan aportar soluciones.
El equipo investigador está formado por profesores que imparten docencia en tres áreas de conocimiento adscritas a la Facultad de Ciencias Sociales y de la Comunicación de la Universidad Europea de Madrid. El proyecto de investigación es de carácter multidisciplinar, habiéndose aplicado en cinco asignaturas diferentes, que, a su vez, se imparten en cuatro grados distintos.
Los resultados obtenidos a través de la encuesta realizada muestran que el 85,83% de los estudiantes tienen un alto grado de satisfacción con la actividad a nivel global y valoran muy positivamente las competencias desarrolladas en la actividad.
Gramsci: Power, culture & education
Authors: Mayo Peter 
Published: December 2020

This paper traces the connection between cultural work and power in the thinking and writing of Italian socio-political theorist and strategist, Antonio Gramsci. His rootedness in Marxism and a deep humanistic culture are emphasised as well as how his main conceptual tools (e.g. Hegemony, Intellectuals, ‘Popular Creative Spirit’, Critical Appropriation and ‘National-Popular’) are central to his analyses of different forms of cultural production, intellectual activity and educational developments in his time. The paper dwells on his musings on the ever so pertinent issue of Migration as it found expression in the literature of his time and their implication for reflection on the same issue in more recent times. Importance is given to the role of political and artistic movements of the period such as Futurism and their legacy for present day life. Parallels are drawn between Gramsci’s cultural views and those of later thinkers such as Raymond Williams, Stuart Hall and Henry A. Giroux who often adopt a Gramscian lens in their economic-social-cultural analysis. The core theme of this paper is the influence of culture and cultural workers/intellectuals in the process of social transformation.