bluuebunny/crossref_metadata_2025_split huggingface dataset:
Building a Rapid Autopsy Program – A Step-by-Step Logistics Guide
Authors: Bacon Eliza R , Ihle Kena , Lee Peter P , Waisman James R 
Published: November 2020

Abstract
Background: Rapid Autopsy Programs offer an opportunity to collect tissue from patients immediately after death, providing critical biological material necessary to develop more effective therapies and improve patient outcomes. Here, we present a step-by-step guide to build a cancer-focused Rapid Autopsy Program, based on our own experiences building “The Legacy Project” at the City of Hope Comprehensive Cancer Center. Methods: The linear timeline of events is separated into four phases: 1) Building the Infrastructure, 2) Recruiting and Consenting, 3) Preparing for Death, and 4) Tissue Collection and Follow up. Important considerations and methods for adaptation are discussed throughout the protocol. Discussion: Using these methods, we successfully collected a total of 533 specimens from 9 subjects. The average time from death to last specimen acquisition was 6.1 hours (range: 4.03 – 7.66 hours; median: 5.71 hours). A diverse team with various areas of expertise is critical for successful program implementation. Our goal herein this protocol is to provide a comprehensive framework and foundation for other institutions to use as a model.
Suicide attempt and its associated factors in young women with adolescent pregnancy in Bangladesh: higher risk if shorter post-pregnancy
Authors: Li Jie , Imam Syeda Zerin , Jing Zhengyue , Wang Yi , Zhou Chengchao 
Published: November 2020

Abstract
Background: Adolescent pregnancy is a major public health problem around the world, with higher prevalence in low income countries and it was a risk factor for suicide. We aimed to assess the prevalence of suicide attempts among young women with adolescent pregnancy in Bangladesh and to explore its association with socio-demographics and pregnancy related factors, health status, and social support.Methods: In this cross-sectional study, we surveyed young women with adolescent pregnancy in urban and rural areas in Bangladesh to assess suicide attempts, socio-demographic and pregnancy-related characteristics, perceived health status, and perceived social support. Binary logistic regression analysis was conducted to explore the relationship of the potential related factors with suicide attempts.Results: Among the participating women, 6.5% (61/940) reported suicide attempts in the last 12 months, and majority (88.5%) of the attempts happened within one year after the pregnancy. Participants with more years after first pregnancy (odds ratio (OR) = 0.49, 95%CI = 0.38–0.63) and more perceived social support from friends (OR = 0.71, 95%CI = 0.57–0.88) were less likely to have suicide attempts, and those perceived bad health status compared with good/fair healthy status (OR = 7.73, 95%CI = 2.85–20.99) were more likely to attempt suicide.Conclusions: Women with adolescent pregnancy were at high risk of suicide attempt especially those during the first year post-pregnancy. The risk of suicide attempts attenuated with the time after pregnancy, and perceived social support from friends was a protective factor and perceived bad health status was a risk factor for suicide attempts among young women who have experienced adolescent pregnancy.
Upstream-downstream linkages in Ganges-Brahmaputra-Meghna basin: the hydro-social imperatives
Authors: Pandey Avash , Prakash Anjal , Barua Anamika , Abu Syed Md. , Nepal Santosh 
Published: November 2020

AbstractTo manage the transboundary water resources of the Ganges-Brahmaputra-Meghna (GBM) River Basin, it is important to identify and understand the complex upstream-downstream linkages in the basin. This paper provides a comprehensive overview of social, economic and cultural processes of the GBM Basin and examines existing mechanisms for governing the shared water resources. It draws attention to the uneven power relations between countries that share the basin and how it affects transboundary water governance. The review concludes that the countries need to strengthen cooperation and harness benefits arising from economic, social, and cultural aspects and proposes multilateral cooperation over the existing bilateral cooperation approach in the region.
The Impact of a New Best Practice Advisory on the Management of Diabetic Ketoacidosis
Authors: Alawneh Diala , Younis Moustafa , Hamarshi Majdi S. 
Published: November 2020

Background:
According to the Center for Disease Control and Prevention, diabetic ketoacidosis
(DKA) hospitalization rates have been steadily increasing. Due to the increasing incidence
and the economic impact associated with its morbidity and treatment, effective management
is key. We aimed to streamline the management of DKA in our intensive care units (ICU) by implementing
a Best-Practice Advisory (BPA) that notifies providers when DKA has resolved.

Methods:
A BPA was implemented on 9/15/2018. We conducted a retrospective review of patients
admitted to the ICU with DKA a year before and after 9/15/2018. Adults (≥18 age) meeting DKA
criteria on admission and treated with continuous insulin infusion (CII) were included. Pre-intervention
group included patients admitted before BPA implementation and post-intervention group included
patients admitted after. Summary and univariate analyses were performed.

Results:
A total of 282 patients were included; 162 (57%) pre-intervention and 120 (43%) post-intervention.
Mean (±SD) age of the patients was 44 (±17) years. There was no significant difference
in baseline characteristics such as age, sex, race, BMI, HbA1c, initial blood glucose, anion gap or
bicarbonate concentration between both the groups (p>0.05). Mean (±SD) total time on CII in
hours was significantly lower in the post-intervention group 14.8 (±7.7) vs. 17.5 (±14.3) p=0.041,
95% CI: 0.11-5.3. The incidence of hypoglycemia was lower in the post-intervention group n=4
(3%) vs. 17 (10%), p=0.024. There was no significant difference in hypokalemia, mortality, LOS
or ICU stay between both the groups (p>0.05).

Conclusions:
The BPA introduced in our DKA management algorithm successfully reduced the total
time on insulin and the incidence of hypoglycemia.
Cardiovascular Manifestations of COVID-19
Authors: Nandy Sneha , Wan Siu-Hin , Brenes-Salazar Jorge 
Published: November 2020

Abstract:
Coronavirus disease 2019 (COVID-19) first emerged in a group of patients who presented
with severe pneumonia in Wuhan, China, in December 2019. A novel virus, now called SARSCoV-
2 (Severe Acute Respiratory Syndrome Coronavirus-2), was isolated from lower respiratory
tract samples. The current outbreak of infection has spread to over 100 countries and killed more
than 340,000 people as of 25th May, 2020.
The predominant clinical manifestation of COVID-19 is a respiratory disease- ranging from mild
flu-like symptoms to fulminant pneumonia and Acute Respiratory Distress Syndrome (ARDS). Patients
with pre-existing cardiovascular risk factors are considered more susceptible to the virus, and
these conditions are often worsened by the infection. Furthermore, COVID-19 infection has led to
de novo cardiac complications, like acute myocardial injury and arrhythmias.
In this review, we have focused on the cardiovascular manifestations of COVID-19 infection that
have been reported in the literature so far. We have also outlined the effect of pre-existing cardiovascular
disease as well as risk factors on the clinical course and outcomes of COVID-19 infection.
Predicting Health Disparities in Regions at Risk of Severe Illness to Inform Health Care Resource Allocation During Pandemics: Observational Study
Authors: Fusillo Tara 
Published: November 2020

Background
Pandemics including COVID-19 have disproportionately affected socioeconomically vulnerable populations.

Objective
Our objective was to create a repeatable modeling process to identify regional population centers with pandemic vulnerability.

Methods
Using readily available COVID-19 and socioeconomic variable data sets, we used stepwise linear regression techniques to build predictive models during the early days of the COVID-19 pandemic. The models were validated later in the pandemic timeline using actual COVID-19 mortality rates in high population density states. The mean sample size was 43 and ranged from 8 (Connecticut) to 82 (Michigan).

Results
The New York, New Jersey, Connecticut, Massachusetts, Louisiana, Michigan, and Pennsylvania models provided the strongest predictions of top counties in densely populated states with a high likelihood of disproportionate COVID-19 mortality rates. For all of these models, P values were less than .05.

Conclusions
The models have been shared with the Department of Health Commissioners of each of these states with strong model predictions as input into a much needed “pandemic playbook” for local health care agencies in allocating medical testing and treatment resources. We have also confirmed the utility of our models with pharmaceutical companies for use in decisions pertaining to vaccine trial and distribution locations.
Revitalizing Cultural Characteristics in Advertising in Nigeria Within a Sketch of Systemic Paradigm
Authors: Dalamu Taofeek Olaiwola , Ogunlusi Gbenga 
Published: November 2020

This study investigated cultural pieces of advertising to indicate the ways that publicists deploy socio-cultural resources as normative channels of persuading readers to consumption. To achieve that goal, ten advertisements of financial, food, and telecommunications industries, harvested from The Punch newspaper, the Internet and erected advertising frameworks, functioned as data of analysis. After stratifying the advertisements into appropriate organizations, the terminology of ‘Below the clause’, functioned as the processing instrument. This allowed the application of graphic illustrations to account for the frequency of communicative components. The analysis revealed the employment of nominal groups (the lessons; this Eid) as playing dominant roles in the constructs, verbal groups (taste; celebrate) and prepositional phrases (from all of us at Fidelity Bank®; of commerce), also operated as stimulating structures. Although negligible, minor clause (Happy Workers’ Day; Eid Mubarak) are relevant grammatical elements of inducement. Besides anchorage and relaying functions interlocking the texts, one observed ambiguity (your work; Bae) in the Union Bank® and Wema Bank® advertisements. Connotations facilitated the communication of Mama don land and the big bottle of Coca-Cola®; the spirit of our nation and green-white-green dresses; your work and Maman Aisha; and the sacrifice of Christ with the crown of thorns. Contexts such as Yorùbá traditions, family ffairs, religious nuances, savings, and historical notions are propagated cultural endowments that influenced the advertisements’ meaning potential. As a result, the analysts might suggest that advertisers ought to consistently decorate their campaigns with cultural fortunes. Such behavior has the capacity to educate and influence readers to consumption in their various regional domains.
Planning for Substantive Testing at the Assertion Level: A Training Activity and Mini Case
Authors: Rummell Janice E. , Weickgenannt Andrea B. 
Published: November 2020

SUMMARY
This two-part educational resource was developed to enhance students' understanding of a key aspect of the audit guidance concerning financial statement audit planning for substantive testing at the assertion level. Assuming the role of audit associates at a CPA firm, students first engage in a training activity in which they deconstruct substantive audit tasks into significant financial statement accounts, management assertions, and types of audit procedures related to each task. Then, students consider inherent risk factors for a client engagement in a mini case and apply relevant accounts, management assertions, and detailed substantive audit procedures. These resources are easy to implement and require little advanced preparation, yet they provide a rich instructional resource for either new or experienced auditing faculty. Assessment results and student survey responses reveal the effectiveness of these resources in promoting students' comprehension of the critical role of management assertions in the audit planning process.
Agent-Based Computational Economics in Management Accounting Research: Opportunities and Difficulties
Authors: Wall Friederike , Leitner Stephan 
Published: November 2020

ABSTRACT
Agent-based computational economics (ACE)—while adopted comparably widely in other domains of managerial science—is a rather novel paradigm for management accounting research (MAR). This paper provides an overview of opportunities and difficulties that ACE may have for research in management accounting and, in particular, introduces a framework that researchers in management accounting may employ when considering ACE as a paradigm for their particular research endeavor. The framework builds on the two interrelated paradigmatic elements of ACE: a set of theoretical assumptions on economic agents and the approach of agent-based modeling. Particular focus is put on contrasting opportunities and difficulties of ACE in comparison to other research methods employed in MAR.
JEL Classifications: C63; D8; D91; M40.
Diagnosis of Neuropathy and Risk Factors for Corneal Nerve Loss in Type 1 and Type 2 Diabetes: A Corneal Confocal Microscopy Study
Authors: Ferdousi Maryam , Kalteniece Alise , Azmi Shazli , Petropoulos Ioannis N. , Ponirakis Georgios , Alam Uazman , Asghar Omar , Marshall Andrew , Fullwood Catherine , Jeziorska Maria , Abbott Caroline , Lauria Giuseppe , Faber Catharina G. , Soran Handrean , Efron Nathan , Boulton Andrew J.M. , Malik Rayaz A. 
Published: November 2020

OBJECTIVE
To assess the diagnostic utility of corneal confocal microscopy (CCM) for diabetic peripheral neuropathy (DPN) and the risk factors for corneal nerve loss.

RESEARCH DESIGN AND METHODS
A total of 490 participants, including 72 healthy control subjects, 149 with type 1 diabetes, and 269 with type 2 diabetes, underwent detailed assessment of peripheral neuropathy and CCM in relation to risk factors.

RESULTS
Corneal nerve fiber density (CNFD) (P &lt; 0.0001 and P &lt; 0.0001), corneal nerve fiber branch density (CNBD) (P &lt; 0.0001 and P &lt; 0.0001), and corneal nerve fiber length (CNFL) (P &lt; 0.0001 and P = 0.02) were significantly lower in patients with type 1 and type 2 diabetes compared with control subjects. CNFD (P &lt; 0.0001), CNBD (P &lt; 0.0001), and CNFL (P &lt; 0.0001) were lower in type 1 diabetes compared with type 2 diabetes. Receiver operating characteristic curve analysis for the diagnosis of DPN demonstrated a good area under the curve for CNFD of 0.81, CNBD of 0.74, and CNFL of 0.73. Multivariable regression analysis showed a significant association among reduced CNFL with age (β = −0.27, P = 0.007), HbA1c (β = −1.1; P = 0.01), and weight (β = −0.14; P = 0.03) in patients with type 2 diabetes and with duration of diabetes (β = −0.13; P = 0.02), LDL cholesterol (β = 1.8, P = 0.04), and triglycerides (β = −2.87; P = 0.009) in patients with type 1 diabetes.

CONCLUSIONS
CCM identifies more severe corneal nerve loss in patients with type 1 diabetes compared with type 2 diabetes and shows good diagnostic accuracy for DPN. Furthermore, the risk factors for a reduction in corneal nerve fiber length differ between type 1 and type 2 diabetes.
EFEKTIVITAS MODELPEMBELAJARAN KOOPERATIF TIPE TALKING CHIPS TERHADAP KEMAMPUAN MENULIS TEKS PROSEDUR KOMPLEKS SISWA KELAS XI SMA NEGERI 7 MEDAN TAHUN PEMBELAJARAN 2019/2020
Authors: Bosko Marbun Yandi Johannes , Wasilah Atika 
Published: November 2020

Penelitian ini bertujuan untuk mengetahui keefektifan model pembelajaran kooperatif tipe talking chipsterhadap kemampuan menulis teks prosedur kompleks siswa kelas XI SMA Negeri 7 Medan Tahun Pembelajaran 2019/2020.Sampel penelitian ini adalah kelas XI-IPA 1 berjumlah 34 dan kelas XI- IPA 2 yang berjumlah 34 siswa. Penelitian ini menggunakan metode eksperimen Randomized Subject, Posstest Only Control Groub Design. Instrumen yang digunakan adalah tes objektif esai.Berdasarkan pengolahan data diperoleh hasil poss-test (Kontrol) dengan rata-rata = 70 dan standar deviasi = 7.17. Sedangkan hasil posttest (Eksperimen) dengan rata-rata = 80.58 dan standar deviasi = 7.74. Dari uji data kelas kontroldan kelas eksperimen diketahui bahwa kedua data tersebut berdistribusi normal. Data post-test (Kontrol) diperoleh Lhitung<Ltabel (0.140 < 0.151) dan data post-test (Eksperimen)diperoleh Lhitung<Ltabel (0.137 < 0.151).Sedangkan dari uji homogenitas diperoleh bahwa sampel penelitian ini berasal dari kelompok yang homogen yaitu < (1.07 < 1.80). Setelah uji normalitas dan homogenitas dilakukan, diperoleh = 5.81. Selanjutnya Dikonsultasikan dengan t tabel pada taraf signifikan 5% dengan df = N-1 = 68-1 = 67 diperoleh taraf signifikan 5%= 2,00.Oleh karena Yang diperoleh lebih besar dar Yaitu 5.81 > 2,00, maka Diterima.Hal ini membuktikan bahwa model pembelajaran kooperatif tipe talking chips efektif digunakan terhadap kemampuan menulis teks prosedur kompleks pada siswa kelas XI SMA Negeri 7 Medan Tahun Pembelajaran 2019/2020.
Analisis Keterampilan Metakognitif Siswa pada Pembelajaran Saintifik Materi Keanekaragaman Hayati
Authors: Agati Fanindria , Hasruddin Hasruddin , Hasibuan Ikhwan 
Published: November 2020

Penelitian ini bertujuan untuk mengetahui keterampilan metakognitif siswa pada pembelajaran saintifik di kelas X SMA Negeri 1 Labuhan Deli T.P 2018/2019. Populasi dari penelitian ini adalah seluruh siswa kelas X MIA T.P 2018/2019 di SMA Negeri 1 Labuhan Deli yang terdiri dari 4 kelas. Sampel dalam penelitian ini sebanyak 1 kelas (36 siswa) yang diambil secara acak. Teknik pengumpulan data dilakukan melalui angket, soal dan lembar observasi yang ditujukan pada siswa dan wawancara kepada guru bidang studi biologi. Hasil analisis data yang diperoleh adalah persentase keterampilan metakognitif siswa berdasarkan hasil angket adalah 72% dalam kriteria tinggi, berdasarkan hasil essay test sebesar 55.6% berada pada kriteria sedang dan persentase rata-rata hasil observasi pembelajaran saintifik terhadap siswa sebesar 57% berada pada tingkatan kriteria sedang. Berdasarkan hasil analisis data diperoleh nilai r= 0.83 dengan pengujian hipotesis menggunakan uji t dengan hasil t hitung > t tabel=15.61 > 2.028 berarti H0 ditolak dan Ha diterima sehingga dapat disimpulkan bahwa terdapat hubungan keterampilan metakognitif dengan pembelajaran saintifik.
Pengaruh Model Pembelajaran Kooperatif Tipe Think-Pair-Share (TPS) Disertai Media Gambar Terhadap Kemampuan Berpikir Kritis Peserta Didik Pada Materi Sel Di Kelas XI MIA SMA Negeri 2 Kabanjahe T.P. 2018/2019
Authors: Simanungkalit Eva Hennita , Gaol Adriana Y.D.L , Karo Dasni 
Published: November 2020

ABSTRAK Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran kooperatif tipe think-pair-share (TPS) disertai media gambar terhadap kemampuan berpikir kritis peserta didik pada materi sel di kelas XI MIA SMA Negeri 2 Kabanjahe tahun pelajaran 2018/2019. Jenis penelitian ini adalah quasi eksperimen. Populasinya adalah seluruh peserta didik kelas XI MIA SMA Negeri 2 Kabanjahe yang terdiri atas 6 kelas dengan 2 kelas sampel yang diambil secara purposif sampel. Sampel yang digunakan adalah kelas XI MIA 4 sebagai kelas eksperimen dan kelas XI MIA 5 sebagai kelas kontrol. Instrumen yang digunakan berjumlah 25 soal sesuai dengan jenis soal berpikir kritis Watson-Glaser Critical Appraisal (W-GCTA) yang dikembangkan oleh peneliti sendiri. Hasil penelitian menunjukkan (1) nilai rata-rata postes kemampuan berpikir kritis peserta didik kelas eksperimen lebih tinggi yaitu 76,56 (SD = 8,08). Dibandingkan nilai rata-rata postes kemampuan berpikir kritis peserta didik kelas kontrol yaitu 71,33 (SD = 8,84). (2) Analisis pengujian hipotesis hasil kemampuan berpikir kritis peserta didik menggunakan uji-t dengan taraf kepercayaan α = 0,05 menunjukkan thitung > ttabel (3,0946 > 1,9967) dan dk = n+n-2 = 70, yang berarti dalam penelitian ini H0 ditolak sedangkan Ha diterima. Dengan demikian menunjukan bahwa ada pengaruh signifikan model pembelajaran kooperatif tipe think-pair-share (TPS) disertai media gambar terhadap kemampuan berpikir kritis siswa. Kata kunci : Think-Pair-Share (TPS), Media Gambar, Kemampuan berpikir kritis
PRAKTIKALITAS MODUL MEDIA PEMBELAJARAN BIOLOGI BERBASIS PROJECT BASED LEARNING (PjBL)
Authors: Susanti Diana , Fitriani Vivi , Sari Liza Yulia 
Published: November 2020

Media pembelajaran biologi mengajarkan mahasiswa untuk menciptakan media di SMP/SMA. Dalam pelaksanaan perkuliahan media yang diciptakan mahasiswa banyak yang tidak sesuai dengan tujuan pembelajaran, selain itu bahan ajar yang tersedia untuk membantu mahasiswa dalam menciptakan media biologi SMP/SMA tersebut belum memadai. Maka dikembangkan modul media pembelajaran biologi berorientasi Project Based Learning (PjBL). Pengembangan modul tersebut telah dilakukan sampai tahap validitas dengan hasil sangat valid. Tujuan dari penelitian ini adalah melihat hasil praktikalitas modul media pembelajaran biologi berbasis project based learning (pjBL). Penelitian ini merupakan penelitain pengembangan menggunakan model pengembangan 4-D yang terdiri atas 4 tahap yaitu define, design, develop, and disseminate. Pada penelitian ini hanya tahap develop yaitu uji praktikalitas. Data penelitian diperoleh dari angket praktikalitas yang diberikan pada dosen dan mahasiswa dan diolah dengan analisis deskriptif. Hasil praktikalitas oleh dosen memperoleh rerata 96,17% (sangat praktis) dan rerata mahasiswa 81,90% (sangat praktis). Kesimpulan dari penelitian ini adalah dihasilkan modul media pembelajaran biologi berorientasi Project Based Learning (PjBL) sangat praktis dari dosen dan mahasiswa.
ANALISIS KOMPETENSI GURU DALAM PENGUASAAN TEKNOLOGI INFORMASI DAN KOMUNIKASI PADA PEMBELAJARAN DI SEKOLAH DASAR NEGERI 2 PURBALINGGA LOR
Authors: Adz Dzaky Sahid Zuhdi , Badarudin Badarudin , Muslim Aji Heru 
Published: November 2020

This research focuses on teacher competencies in the use and utilization of information and communication technology in learning. The purpose is to analyze and describe teacher competencies in the use of information and communication technology in learning in a school. The study was conducted using a qualitative descriptive approach. This research was conducted using observation through direct interviews with informants consisting of school principals, class teachers and students. Data validity uses triangulation and reflection. The results show that teachers at SDN 02 Purbalingga Lor have been able and able to use, utilize and collaborate information and communication technology with learning in the classroom. Although in addition there are also constraints both internal and external. Support from related agencies was immediately felt both by the students and by the teachers as users. Principals with their full support also continue to encourage teachers to always innovate, especially in the use of information and communication technology in learning, both in the classroom and outside the classroom.Keywords: Teacher competence, information and communication technology, elementary school.