bluuebunny/crossref_metadata_2025_split huggingface dataset:
Real-World Assessment of the Impact of Erectile Dysfunction on Sexual Planning Behavior and Health- and Treatment-Related Outcomes Among Men in 8 Countries
Authors: Goldstein Irwin , Giraldi Annamaria , Maculaitis Martine C. , Li Vicky W. , Hartzell-Cushanick Rose , Hassan Tarek A. 
Published: June 2020

Abstract

Introduction
The effect of erectile dysfunction (ED) on sexual planning behaviors and outcomes in men taking phosphodiesterase type 5 inhibitors (PDE5Is) is not well studied.

Aims
To assess sexual habits, behaviors, and treatment-related outcomes of PDE5I-treated men with ED.

Methods
This cross-sectional observational study recruited men aged 30 to 70 years with mild-to-severe ED from 8 diverse countries (the United States, the United Kingdom, Italy, Russia, Turkey, Israel, China, and Japan) to complete an approximately 15-minute survey. Differences were evaluated using bivariate analyses, and data were summarized using descriptive statistics.

Main Outcome Measures
Self-reported data were collected for demographics, health characteristics, treatment, sexual habits, ED severity, ED-specific quality of life, and treatment satisfaction.

Results
The survey was completed by 1,575 men. Mean frequency of sexual intercourse was 5.7 times/month. Overall, 87.1% of men always, often, or sometimes planned for sexual activity. Of those planning in advance, 32.8% and 40.6% agreed or strongly agreed that they plan for specific days of the week and times of day, respectively. Sexual planning habits were similar for patients taking short-acting vs long-acting PDE5Is. The most commonly cited reasons for planning sexual activity were needing time to take medication (48.4%), needing to make sure medication has taken effect (43.4%), convenient time for sexual activity (34.9%), and needing the partner’s agreement (33.4%). Mean Self-Esteem and Relationship Questionnaire total score was 56.4.

Conclusions
The differences in ED burden and sexual planning behavior observed across countries were not influenced by the type of PDE5I being taken, suggesting that cultural differences are an important factor when considering types of ED treatment. These findings provide a better understanding of burden, sexual habits, planning behaviors, quality of life, and treatment-related outcomes among PDE5I-treated men with ED in 8 Western and non-Western countries and may aid healthcare providers in selecting optimal treatments.
Goldstein I, Giraldi A, Maculaitis MC, Real-World Assessment of the Impact of Erectile Dysfunction on Sexual Planning Behavior and Health- and Treatment-Related Outcomes Among Men in 8 Countries. J Sex Med 2020;8:338–349.
A Statistical Analysis of Global Ionospheric E‐Layer Scintillation During 2007–2014
Authors: Li Q. B. , Huang Z. , Chen S. 
Published: June 2020

AbstractThis paper presents the global three‐dimensional morphology and seasonal variation of the scintillation index at E‐layer altitudes varying from 70 to 140 km. An attempt is conducted to analyze the scintillation distribution in different latitude bins and to explore solar and geomagnetic activity‐dependent characteristic of E‐layer scintillations. The scintillation index is derived from the signal‐to‐noise ratio intensity fluctuations of L1 channels in GPS radio occultation (RO) using the Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) during 2007–2014. The results show that the summer scintillation index has the greatest values, followed by the winter, autumn, and spring months. The summer scintillation is in close connection with the solar radiation intensity and sunshine duration, but it exhibits seasonal asymmetry whereby the summer scintillation in the northern hemisphere is more intense than in the southern hemisphere. Meanwhile, the scintillation in the autumn hemisphere is slightly more intense than in the spring hemisphere in approximately midlatitude regions during most daytimes. The conspicuous scintillation activity in the middle and low latitudes starts post‐sunrise and often persists until post‐midnight. Some observed results show that the greatest scintillation occurrence rate of the latitude profile occurs at approximately sunset and at an altitude range of 100–120 km in the middle‐low latitudes. Additionally, the enhanced solar activity possibly can result in the slight decrease of scintillation occurrence, and geomagnetic activity has slight effect on E‐layer scintillation in most cases.
A Case Study of the Daytime Intense Radar Backscatter and Strong Ionospheric Scintillation Related to the Low‐Latitude E‐Region Irregularities
Authors: Chen Gang , Wang Zhihua , Jin Han , Yan Chunxiao , Zhang Shaodong , Feng Jian , Gong Wanlin , He Zhiqiu 
Published: June 2020

AbstractThe special daytime echoes, which present the V‐shaped echo pattern between 90–180 km ranges in the range‐time‐intensity (RTI) plot, were occasionally recorded by the Hainan coherent scatter phased array radar (HCOPAR) located at the low latitude of China. Four cases with distinct echo traces are presented to display the common characteristics of the V‐shaped echoes. They usually occur between 10:00–15:00 LT in the daytime with the enhanced top frequency and blanketing frequency of Es layer (ftEs and fbEs). Their left/right wings present negative/positive Doppler velocity. A case on 16 August 2015 was investigated by the joint observation of the HCOPAR, the Hainan Digisonde, and a scintillation receiver. The echo spectra show that the V‐shaped echoes were backscattered from the type 2 irregularities. The formation of the V‐shaped echo pattern was due to the leakage of the antenna sidelobe for the very intense scatter from Es layer. The irregularities were found traveling westward with the velocity of 41.12 ± 2.08 m/s. While the occurrence of the intense irregularities, there were periodic peaks appearing on the ftEs and fbEs curves, and the maximum ftEs‐fbEs reached 10.31 MHz. At the same time, the strong ionospheric scintillation event was recorded by the scintillation receiver. The wind shear is considered to produce the sharp density gradient in the Es plasma and then induce the gradient drift instability. The large‐scale gravity waves have the possibility to induce the E‐region wind shear.
Permeability Profiles Across the Crust‐Mantle Sections in the Oman Drilling Project Inferred From Dry and Wet Resistivity Data
Authors: Katayama Ikuo , Abe Natsue , Hatakeyama Kohei , Akamatsu Yuya , Okazaki Keishi , Ulven Ole Ivar , Hong Gilbert , Zhu Wenlu , Cordonnier Benoit , Michibayashi Katsuyoshi , Godard Marguerite , Kelemen Peter ,   the Oman Drilling Project Phase 2 Science Party
Published: June 2020

AbstractPermeability profiles in the crust‐mantle sequences of the Samail ophiolite were constructed based on onboard measurements of the electrical resistivity of cores recovered during the Oman Drilling Project. For each sample, we measured dry and brine‐saturated resistivity during the description campaign on the drilling vessel Chikyu. Owing to the conductive brine in the pore space, wet resistivity is systematically lower than dry resistivity. The difference between dry and wet resistivity is attributed to the movement of dissolved ions in brine that occupies the pore space. We applied effective medium theory to calculate the volume fraction of pores that contribute to electrical transport. Using an empirical cubic law between transport porosity and permeability, we constructed permeability profiles for the crust‐mantle transition zone and the serpentinized mantle sections in the Samail ophiolite. The results indicate that (1) the gabbro sequence has a markedly lower permeability than the underlying mantle sequence; (2) serpentinized dunites have higher permeability than serpentinized harzburgites; and (3) discrete sample permeability is correlated with ultrasonic velocity, suggesting that the permeability variations predominately reflect crack density and geometry.
Revisiting the Sulfur‐Water Chemical System in the Middle Atmosphere of Venus
Authors: Shao Wencheng D. , Zhang Xi , Bierson Carver J. , Encrenaz Therese 
Published: June 2020

AbstractSulfur‐water chemistry plays an important role in the middle atmosphere of Venus. Ground‐based observations have found that simultaneously observed SO2 and H2O at ~64 km vary with time and are temporally anticorrelated. To understand these observations, we explore the sulfur‐water chemical system using a one‐dimensional chemistry‐diffusion model. We find that SO2 and H2O mixing ratios above the clouds are highly dependent on mixing ratios of the two species at the middle cloud top (58 km). The behavior of sulfur‐water chemical system can be classified into three regimes, but there is no abrupt transition among these regimes. In particular, there is no bifurcation behavior as previously claimed. We also find that the SO2 self‐shielding effect causes H2O above the clouds to respond to the middle cloud top in a nonmonotonic fashion. Through comparison with observations, we find that mixing ratio variations at the middle cloud top can explain the observed variability of SO2 and H2O. The sulfur‐water chemistry in the middle atmosphere is responsible for the H2O‐SO2 anticorrelation at 64 km. Eddy transport change alone cannot explain the variations of both species. These results imply that variations of species abundance in the middle atmosphere are significantly influenced by the lower atmospheric processes. Continued ground‐based measurements of the coevolution of SO2 and H2O above the clouds and new spacecraft missions will be crucial for uncovering the complicated processes underlying the interaction among the lower atmosphere, the clouds, and the middle atmosphere of Venus.
Quantifying Water Scarcity in Northern China Within the Context of Climatic and Societal Changes and South‐to‐North Water Diversion
Authors: Yin Yuanyuan , Wang Lei , Wang Zhongjing , Tang Qiuhong , Piao Shilong , Chen Deliang , Xia Jun , Conradt Tobias , Liu Junguo , Wada Yoshihide , Cai Ximing , Xie Zhenghui , Duan Qingyun , Li Xiuping , Zhou Jing , Zhang Jianyun 
Published: June 2020

AbstractWith the increasing pressure from population growth and economic development, northern China (NC) faces a grand challenge of water scarcity, which can be further exacerbated by climatic and societal changes. The South‐to‐North Water Diversion (SNWD) project is designed to mitigate the water scarcity in NC. However, few studies have quantified the impact of the SNWD on water scarcity within the context of climatic and societal changes and its potential effects on economic and agricultural food in the region. We used water supply stress index (WaSSI) to quantify water scarcity within the context of environmental change in NC and developed a method to estimate the economic and agricultural impacts of the SNWD. Focuses were put on alleviating the water supply shortage and economic and agricultural benefits for the water‐receiving NC. We find that societal changes, especially economic growth, are the major contributors to water scarcity in NC during 2009–2099. To completely mitigate the water scarcity of NC, at least an additional water supply of 13 billion m3/year (comparable to the annual diversion water by SNWD Central Route) will be necessary. Although SNWD alone cannot provide the full solution to NC's water shortage in next few decades, it can significantly alleviate the water supply stress in NC (particularly Beijing), considerably increasing the agricultural production (more than 115 Tcal/year) and bringing economic benefits (more than 51 billion RMB/year) through supplying industrial and domestic water use. Additionally, the transfer project could have impacts on the ecological environment in the exporting regions.
The Disappearing Lake: A Historical Analysis of Drought and the Salton Sea in the Context of the GeoHealth Framework
Authors: Doede Aubrey L. , DeGuzman Pamela B. 
Published: June 2020

AbstractThe Imperial Valley region of Southeastern California has become one of the most productive agricultural regions in the state and has the highest rates of childhood asthma in California. Lack of precipitation in the Imperial Valley has caused the water level of the Salton Sea to recede to a record low since its formation in the early 1900s. Previous studies of wind and dust deposition conducted in other regions have shown how reduced precipitation, ground heating, and the diminishing water level in an arid climate pose a risk of exposing previously sequestered toxic chemicals to open air, adversely affecting lung health. The purpose of this study is to draw historical parallels between the Aral Sea and Salton Sea in the context of geomorphology, ecology, human health, economics, and human migration, to inform an assessment of environmentally related health impacts of those living in the Imperial Valley region. Future droughts and heatwaves are expected to rise in frequency and severity, disproportionately affecting those impacted by financial and health disparities. Future research must include the implications of population health in the context of GeoHealth as a result of the most recent drought and the receding water levels of the Salton Sea.
Stress Field Interactions Between Overlapping Shield Volcanoes: Borehole Breakout Evidence From the Island of Hawai'i, USA
Authors: Pierdominici Simona , Millett John M. , Kück Jochem K. M. , Thomas Donald , Jerram Dougal A. , Planke Sverre , Haskins Eric , Lautze Nicole , Galland Olivier 
Published: June 2020

AbstractKnowledge of the in situ stress state of the Earth's crust plays a key role in understanding geological processes including plate tectonics, earthquakes, slope failure, and igneous emplacement. In this paper, we determine the in situ stress orientation from the PTA2 borehole on the island of Hawai'i, drilled into a lava flow dominated sequence between Mauna Kea and Mauna Loa. High‐resolution acoustic images were collected from the open hole interval 886 m to 1,567 m. Based on identification of 371 borehole breakouts for a total length of 310 m, the mean orientation of the minimum horizontal principal stress is N106° and remains constant across different volcanic rock fabrics. Changes in borehole breakout shape are linked to the different strength of volcanic facies and intra‐facies. The orientation of the present‐day stress field at Mauna Kea deviates from the plate forces and regional tectonic stress field. We interpret the compressive stress regime at the PTA2 site as resulting from the competing gravitational fields of the large topographic highs of Mauna Kea and Mauna Loa. Our study reveals that the mass accumulation associated with shield volcano growth imparts significant local variations to the subsurface stress state on volcanic islands consisting of overlapping shield volcanoes. The results have significant implications for stress accumulation leading to brittle failure and flank collapse, along with potentially influencing magma accumulation and ascent pathways during volcanic island evolution. This study provides the first insights into the orientation of the present‐day stress field between the major island forming shield volcanoes of Hawai'i.
Megaripple Migration on Mars
Authors: Silvestro S. , Chojnacki M. , Vaz D. A. , Cardinale M. , Yizhaq H. , Esposito F. 
Published: June 2020

AbstractAeolian megaripples, with 5‐ to 50‐m spacing, are abundant on the surface of Mars. These features were repeatedly targeted by high‐resolution orbital images, but they have never been observed to move. Thus, aeolian megaripples (especially the bright‐toned ones often referred as Transverse Aeolian Ridges—TARs) have been interpreted as relict features of a past climate. In this report, we show evidence for the migration of bright‐toned megaripples spaced 1 to 35 m (5 m on average) in two equatorial areas on Mars indicating that megaripples and small TARs can be active today. The moving megaripples display sand fluxes that are 2 orders of magnitudes lower than the surrounding dunes on average and, unlike similar bedforms on Earth, can migrate obliquely and longitudinally. In addition, the active megaripples in the two study areas of Syrtis Major and Mawrth Vallis show very similar flux distributions, echoing the similarities between dune crest fluxes in the two study areas and suggesting the existence of a relationship between dune and megaripple fluxes that can be explored elsewhere. Active megaripples, together with high‐sand flux dunes, represent a key indicator of strong winds at the surface of Mars. A past climate with a denser atmosphere is not necessary to explain their accumulation and migration.
Hurricane Deposits on Carbonate Platforms: A Case Study of Hurricane Irma Deposits on Little Ambergris Cay, Turks and Caicos Islands
Authors: Jamison‐Todd Sarah , Stein Nathan , Overeem Irina , Khalid Arslaan , Trower Elizabeth J. 
Published: June 2020

AbstractThe study of modern hurricane deposits is useful in both identifying ancient hurricane deposits in the rock record and predicting patterns of deposition and erosion produced by future storm events. Hurricane deposits on carbonate platforms have been studied less frequently than have been those along continental coasts. Here we present observations of the characteristics of deposition and scour caused by Hurricane Irma on Little Ambergris Cay, a small uninhabited island located near the southeastern edge of the Caicos platform in the Turks and Caicos Islands. Hurricane Irma passed directly over Little Ambergris Cay on 7 September 2017 as a Category 5 hurricane. We described and sampled multiple types of hurricane deposits and determined that the washover fans were the best sedimentological records for hurricane conditions, as they were subject to very little reworking over time. We compared different model predictions of storm tide and wave height with eyewitness reports and distributions of scour. Examining the washover fans allowed for the construction of a conceptual model for hurricane deposits formed in a high‐energy storm event on a carbonate platform. Characteristics of the washover fans were their small size, the lack of sedimentary structures, and very well sorted sediment. The size and distribution of carbonate boulders eroded and transported by the storm are consistent with depth‐averaged flow velocities in the range of 1.5–5.3 m/s. The strength of the storm and the low‐lying topography, distinct features of a carbonate platform setting, contributed to high levels of sediment bypass and high flow velocities, resulting in small, unstructured deposits.
Bistatic Observations With SuperDARN HF Radars: First Results
Authors: Shepherd S. G. , Sterne K. T. , Thomas E. G. , Ruohoniemi J. M. , Baker J. B. H. , Parris R. T. , Pedersen T. R. , Holmes J. M. 
Published: June 2020

AbstractSuper Dual Auroral Radar Network (SuperDARN) radars operate in a coordinated but monostatic configuration whereby high‐frequency (HF) signals scattered from ionospheric density irregularities or from the surface of the Earth return to the transmitting radar where Doppler parameters are then acquired. A bistatic arrangement has been developed for SuperDARN radars in which HF signals transmitted from one radar are received and analyzed by another radar that is separated by a large distance (>1,000 km). This new capability was developed and tested on radars located in Oregon and Kansas. Numerous 3‐day bistatic campaigns have been conducted over a period extending from September 2019 through March 2020. During these campaigns three distinct bistatic propagation modes have been identified including a direct mode in which signals are transmitted and received through the radar side lobes. Direct mode signals propagate along the great‐circle arc connecting the two bistatic radar sites, reflecting from the ionosphere at both E region and F region altitudes. Two additional modes are observed in which HF signals transmitted from one radar scatter from either ionospheric density irregularities or from the surface of the Earth before propagating to the bistatic receiving radar. Ray tracing simulations performed for examples of each mode show good agreement with observations and confirm our understanding of these three bistatic propagation modes. Bistatic campaigns continue to be scheduled in order to improve technical aspects of this new capability, to further explore the physical processes involved in the propagation and scattering of HF bistatic signals and to expand the coverage of ionospheric effects that is possible with SuperDARN.
Deep Into the Chibougamau Area, Abitibi Greenstone Belt: Structure of a Neoarchean Crust Revealed by Seismic Reflection Profiling
Authors: Mathieu Lucie , Snyder David B. , Bedeaux Pierre , Cheraghi Saeid , Lafrance Bruno , Thurston Phil , Sherlock Ross 
Published: June 2020

AbstractCopper‐gold magmatic‐hydrothermal systems dominate in the Chibougamau area of the Neoarchean Abitibi subprovince (greenstone belt) of the Superior Province (craton), whereas orogenic gold mineralization is more common in the rest of the Abitibi. Understanding differences in metal endowment within the Abitibi greenstone belt requires insights into the geodynamic evolution of the Chibougamau area. This was addressed by imaging the crust using seismic reflection profiling acquired as part of the Metal Earth project. Seismic reflection sections display shallowly south‐dipping reflectors located within the upper crust (e.g., a possible deep continuation of the Barlow fault) and a northward‐dipping midcrust imbricated with older crust (Opatica subprovince) to the north. Multiple reflectors characterize the upper part of the midcrust, interpreted as faults superimposed on a major lithological boundary. These structures likely formed during terrane accretion prior to craton stabilization. Combining the new seismic data with known stratigraphic, structural, and magmatic records, we propose that the study area was initially a normal (i.e., thick) Archean oceanic crust that formed at or before 2.80 Ga and that evolved through terrane imbrication at 2.73–2.70 Ga. Shortening caused rapid burial, devolatilization, and partial melting of hydrated mafic rocks to produce tonalite magmas that may have mixed with mantle‐derived melts to produce the diorite‐tonalite suite associated with observed Cu‐Au magmatic‐hydrothermal mineralization.
Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
Authors: Huang Aobo , Tang Yu , Shi Xuetao , Jia Min , Zhu Jinheng , Yan Xiaohan , Chen Huiqin , Gu Yangnan 
Published: June 2020

AbstractThe inner nuclear membrane (INM) selectively accumulates proteins that are essential for nuclear functions; however, overaccumulation of INM proteins results in a range of rare genetic disorders. So far, little is known about how defective, mislocalized, or abnormally accumulated membrane proteins are actively removed from the INM, especially in plants and animals. Here, via analysis of a proximity-labeling proteomic profile of INM-associated proteins in Arabidopsis, we identify critical components for an INM protein degradation pathway. We show that this pathway relies on the CDC48 complex for INM protein extraction and 26S proteasome for subsequent protein degradation. Moreover, we show that CDC48 at the INM may be regulated by a subgroup of PUX proteins, which determine the substrate specificity or affect the ATPase activity of CDC48. These PUX proteins specifically associate with the nucleoskeleton underneath the INM and physically interact with CDC48 proteins to negatively regulate INM protein degradation in plants.