bluuebunny/crossref_metadata_2025_split huggingface dataset:
Keberadaan Perokok dalam Rumah sebagai Faktor Risiko Kejadian Pneumonia pada Anak: Suatu Kajian Sistematik
Authors: Kusumawardani Rahma Desta , Suhartono Suhartono , Budiyono Budiyono 
Published: October 2020

Latar belakang: Pneumonia merupakan penyebab utama kematian pada anak di dunia. Salah satu faktor risiko yang perlu mendapatkan perhatian adalah adanya pajanan asap rokok lingkungan (environmental tobacco smoke, ETS) yang berasal dari adanya perokok dalam rumah. Kajian sistematis ini bertujuan menggambarkan hubungan keberadaan perokok dalam rumah dengan kejadian pneumonia pada anak.Metode: Penelusuran artikel dilakukan melalui database Portal Garuda Indonesia, PubMed, Scopus, dan ProQuest, pada bulan Mei 2020. Kriteria inklusi adalah penelitian dengan desain studi observasional dan fokus pada hubungan pajanan asap rokok dengan pneumonia pada anak, yang dipublikasikan antara tahun 2000-2020.Hasil: Terdapat 8 artikel yang dikaji. Salah satu artikel melakukan pengukuran CCR (Cotinine/creatinine ratio) urin. Faktor terkait pajanan asap rokok yang terbukti berkaitan dengan peningkatan risiko pneumonia adalah adanya anggota keluarga yang merokok, lokasi merokok berada di dalam rumah, adanya bau tembakau di dalam ruangan, pajanan asap rokok pada masa prenatal terutama ibu yang merokok pada masa kehamilan, dan usia anak pada saat terpajan asap rokok.Simpulan: Keberadaan perokok dalam rumah meningkatkan risiko pneumonia pada anak, dengan kisaran 1,2-6,7 ABSTRACTTitle: The existence of smokers in the home as a risk factor of pneumonia in children: A systematic review Background: Pneumonia is the leading cause of death in children worldwide. One of the risk factors that need an attention is exposure to Environmental Tobacco Smoke (ETS) from the smoker in the house. The purpose of this systematic study is to describe relationship between the presence of smokers in the house and pneumonia in children.Methods: The literature search was carried out through the database of Portal Garuda Indonesia, PubMed, Scopus, and ProQuest, which were conducted in May 2020. The inclusion criteria are observational research designs and focus on the relationship between exposure to tobacco smoke and pneumonia in children that were published between 2000 and 2020.Results: Eight articles were selected for review. One of the articles has measured urinary cotinine/creatinine ratio (CCR). Factors related to the exposure to tobacco smoke which is proven to be associated with an increase risk of pneumonia in children were the presence of family members who smoke, location of smoking in the house, the smell of tobacco in the room, exposure to tobacco smoke during the prenatal period especially maternal smoking, and the age of the child when exposed to tobacco smoke. Conclusion: The presence of smokers in the home increases the risk of pneumonia in children, with a ranges between 1.2-6.7
Posterior predictive treatment assignment methods for causal inference in the context of time-varying treatments
Authors: Liao Shirley X. , Henneman Lucas , Zigler Cory 
Published: October 2020

Abstract
Marginal structural models (MSM) with inverse probability weighting (IPW) are used to estimate causal effects of time-varying treatments, but can result in erratic finite-sample performance when there is low overlap in covariate distributions across different treatment patterns. Modifications to IPW which target the average treatment effect (ATE) estimand either introduce bias or rely on unverifiable parametric assumptions and extrapolation. This paper extends an alternate estimand, the ATE on the overlap population (ATO) which is estimated on a sub-population with a reasonable probability of receiving alternate treatment patterns in time-varying treatment settings. To estimate the ATO within an MSM framework, this paper extends a stochastic pruning method based on the posterior predictive treatment assignment (PPTA) (Zigler, C. M., and M. Cefalu. 2017. “Posterior Predictive Treatment Assignment for Estimating Causal Effects with Limited Overlap.” eprint arXiv:1710.08749.) as well as a weighting analog (Li, F., K. L. Morgan, and A. M. Zaslavsky. 2018. “Balancing Covariates via Propensity Score Weighting.” Journal of the American Statistical Association 113: 390–400, https://doi.org/10.1080/01621459.2016.1260466.) to the time-varying treatment setting. Simulations demonstrate the performance of these extensions compared against IPW and stabilized weighting with regard to bias, efficiency, and coverage. Finally, an analysis using these methods is performed on Medicare beneficiaries residing across 18,480 ZIP codes in the U.S. to evaluate the effect of coal-fired power plant emissions exposure on ischemic heart disease (IHD) hospitalization, accounting for seasonal patterns that lead to change in treatment over time.
The violent ground motion before the Jiuzhaigou earthquake Ms7.0
Authors: Xu Kangsheng , Li Ying 
Published: October 2020

Abstract
An Ms7.0 earthquake occurred in Jiuzhaigou, Sichuan Province, China, on August 8, 2017. In this study, we used the vertical component data from 31 seismic stations near the epicenter from May 1 to August 20, 2017, to calculate the amplitude spectrum hourly using the fast Fourier transform method. Furthermore, the spectral area of the low frequency band (0.02–1 Hz), which represents the energy of low frequency motion, was calculated. In this way, the temporal and spatial variations in the vertical ground motion in this region were determined. Four high-value processes occurred in mid-June, mid-July, late July, and early August (the last three are discussed in this article). Based on a comparison with the local meteorological data, the meteorological factors had no influence, local geological factors did not affect the results, and typhoon factors did not show obvious correlation. Combined with the results of previous studies, we believe that the increase in the spectral area reflects the intense movement of deep material in the region related to the Jiuzhaigou earthquake. The spatial distribution of the spectral area (energy) reveals that the deep material moved eastward rapidly, was obstructed by the Sichuan Basin, and expanded to the northwest in a U-shaped channel, which may be the main dynamic factor for the formation or triggering of the earthquake.
Caffeic and chlorogenic acids modulate altered activity of key enzymes linked to hypertension in cyclosporine-induced hypertensive rats
Authors: Agunloye Odunayo M. , Oboh Ganiyu , Bello Gbemisola T. , Oyagbemi Ademola A. 
Published: October 2020

Abstract

Objectives
This study aimed to explore the protective mechanism of caffeic acid (CAA) and chlorogenic acid (CHA) on cyclosporine (CSA) induced hypertensive rats.

Methods
Effect of CAA and CHA on diastolic blood pressure (DBP), mean arterial pressure (MAP), angiotensin-converting enzyme (ACE), e-nucleotide triphosphate dephosphorylase (e-NTPDase), 5′ nucleotidase and adenosine deaminase (ADA) activity in CSA-induced hypertensive rats were determined.

Results
CAA and CHA administration stabilized hypertensive effect caused by CSA administration. Also, altered activity of ACE (lung), e-NTPDase, 5′ nucleotidase, ADA as well as elevated malondiadehyde (MDA) level was restored in all the treated hypertensive rats in comparison with the untreated hypertensive rats.

Conclusion
Hence, these observed results could underlie some of the mechanisms through which CAA and CHA could offer antihypertensive effect.
Mitigative effect of Momordica cymbalaria fruit extract against sodium fluoride induced hepatotoxicity in Wistar male albino rats
Authors: Mitta Raghavendra , Duddu Sushmitha , Pulala Raghuveer Yadav , Bhupalam Pradeepkumar , Mandlem Venkatakirankumar , Konde Abbulu 
Published: October 2020

Abstract

Objectives
The main objective of the present study is to evaluate the mitigative effect of hydroalcoholic extract of Momordica cymbalaria fruits against sodium fluoride (NaF) induced hepatotoxicity.

Methods
In this study, Wistar male albino rats were randomly divided into five groups of six rats each. Group I and II served as normal and toxic controls. Group III as plant control received extract at a dose of 400 mg/kg b. wt, p.o and Groups IV and V as treatment groups received extract at a dose 200 and 400 mg/kg b. wt, p.o for 30 days. All groups except Groups I and III received 100 ppm of NaF through drinking water. After completion of the study, blood collected for the estimation of liver blood serum biomarkers such as aspartate aminotransferases (AST), alanine aminotransferases (ALT), alkaline Phosphatase (ALP), direct and total bilirubin, total protein and albumin. The liver tissue homogenate was for estimation of lipid peroxidation, catalase, and reduced glutathione levels.

Results
The results showed that NaF intoxication caused elevation of liver blood serum levels and lipid peroxidation; decreased levels of serum total protein, albumin and liver reduced glutathione, and catalase observed. The treatment groups showed decreased elevated serum biomarkers (ALT, AST, and ALP), liver lipid peroxidation and increased serum total protein and albumin, liver reduced glutathione and catalase levels in a dose-dependent manner. Histopathological studies also further strongly supported for mitigative effects of the plant.

Conclusions
In conclusion, our findings of the study indicated that M. cymbalaria fruits were a potential drug candidate in the treatment of NaF induced hepatotoxicity.
Temperature monitoring in the subsurface during single lip deep hole drilling
Authors: Wegert Robert , Guski Vinzenz , Möhring Hans-Christian , Schmauder Siegfried 
Published: October 2020

Abstract
The surface quality and the subsurface properties such as hardness, residual stresses and grain size of a drill hole are dependent on the cutting parameters of the single lip deep hole drilling process and therefore on the thermomechanical as-is state in the cutting zone and in the contact zone between the guide pads and the drill hole surface. In this contribution, the main objectives are the in-process measurement of the thermal as-is state in the subsurface of a drilling hole by means of thermocouples as well as the feed force and drilling torque evaluation. FE simulation results to verify the investigations and to predict the thermomechanical conditions in the cutting zone are presented as well. The work is part of an interdisciplinary research project in the framework of the priority program “Surface Conditioning in Machining Processes” (SPP 2086) of the German Research Foundation (DFG).
This contribution provides an overview of the effects of cutting parameters, cooling lubrication and including wear on the thermal conditions in the subsurface and mechanical loads during this machining process. At first, a test set up for the in-process temperature measurement will be presented with the execution as well as the analysis of the resulting temperature, feed force and drilling torque during drilling a 42CrMo4 steel. Furthermore, the results of process simulations and the validation of this applied FE approach with measured quantities are presented.
The ART of apologizing: Entering the black box of an intervention program
Authors: Tholander Michael , Andersson Bruck Kjerstin 
Published: October 2020

AbstractDuring recent decades, evidence-based treatment programs have become a given part of the youth justice system. Typically, such programs are evaluated through quantitative effect studies, in which a variety of outcome measures play a significant role. This case study offers an alternative, interactional evaluation of a treatment program. More specifically, the analysis focuses on an Aggression Replacement Training (ART) session that was held at a youth detention home in Sweden. In this session, two trainers and three detained adolescent boys perform an exercise that serves to teach the latter various apology practices. A detailed, conversation analytic examination of the interaction in the session shows that the trainers repeatedly problematize the boys’ contributions in a kind of deviant-making enterprise. Thus, rather than recognizing competencies that do become visible through closer inspection, the trainers one-sidedly highlight lack and deficiency. It is argued that the interpretative frame of ART, with its focus on pathologization, individualization, and responsibilization, amplifies the incarcerated boys’ deviancy, hence symbolically locking them up in a second, non-material or discursive, sense.
Pencegahan Korupsi Melalui Pencabutan Hak Politik Sebuah Telaah dari Perspektif Pembaruan Hukum Pidana Indonesia
Authors: Fajrin Yaris Adhial , Triwijaya Ach Faisol 
Published: October 2020

Tindak pidana korupsi banyak terjadi akibat penyalahgunaan kekuasaan yang dilakukan oleh pejabat publik, diantaranya kepala daerah Upaya pemberantasan korupsi banyak dilakukan dengan preventif dan represif. Salah satu upaya preventif yang dilakukan adalah dengan memberikan larangan mantan terpidana mencalonkan diri dalam kontes pemilihan umum yang tujuannya untuk mencari pemimpin yang berkualitas. Namun pasca putusan MK Nomor 71/PUU-XIV/2016 mennggambarkan penurunan atau pelemahan pencegahan korupsi di Indonesia. Penulisan ini bertujuan untuk menemkan dasar akademis pentingnya pencegahan korupsi melalui pembatasan sesorang mencalonkan diri dalam jabatan publik. Diperoleh kesimpulan dari penelitian ini yaitu Putusan MK tersebut membuka peluang bagi mantan terpidana korupsi untuk mencalonkan diri. Sehingga sanksi pencabutan hak politik bagi terpidana korupsi yang menjalani sanksi penjara di bawah lima tahun perlu diprioritaskan untuk dijatuhkan. Sinergitas antara dua mekanisme tersebut, diperlukan guna mewujudkan cita-cita pemerintahan yang baik dan bersih, yang berkeadilan sosial. Corruption crimes occurred due to the misuse of power carried out by public officials, among them the regional head of anti-corruption efforts are carried out with preventive and repressive. One of the preventive efforts undertaken is to provide a former criminal ban to run for a general election contest whose goal is to find a qualified leader. However, after the decision of MK No. 71/PUU-XIV/2016, he described the decline or weakening of corruption prevention in Indonesia. This writing aims to accompany the academic basis of the importance of the prevention of corruption through the restriction of a person running in public office. Derived by the conclusion of this research, the COURT award opens an opportunity for former convicted corruption to run. Thus, the sanction of political Rights for criminal corruption under five years of imprisonment must be prioritized to be dropped. Synergity between the two mechanisms, necessary to realize the ideals of good and clean government, the social justice.
Nanocomposite solar cells based on organic/inorganic (clonidine/Si) heterojunction with plasmonic Au nanoparticles
Authors: Mamykin S. , Mamontova I. , Kotova N. , Kondratenko O. , Barlas T. , Romanyuk V. , Smertenko P. P. , Roshchina N. 
Published: October 2020

The peculiarities of optical and electrical properties of organic(clonidine)/inorganic(Si) heterojunction with plasmonic Au nanoparticles have been investigated by reflection spectra, photoelectric and current-voltage characteristics measurements. Porous nanostructured surfaces of silicon wafers were obtained by the method of selective chemical etching initiated by metal (gold) nanoparticles. Nanocomposites based on nanostructured silicon, clonidine and gold nanoparticles have been made. Two types of structure, namely, solar cells and photodiodes on the basis of such heterojunction were analysed. The reflection spectra of light confirmed the excitation of the plasmon mode in nanocomposites with gold nanoparticles. Photoelectric studies have shown an increase of the photocurrent of solar cells obtained as a result of using both nanostructured silicon and gold nanoparticles in 1.5 and 7 times, respectively. Study of the injection properties of the structures showed that the clonidine layer always facilitates the injection of current carriers, while gold nanoparticles limit the current in the case of a flat surface.
Thermodynamic properties of 2H-MoSe2 from first principles quasi-harmonic approximation
Authors: Vasiliev O. 
Published: October 2020

In this paper, we report the results of first-principles calculation of 2H-MoSe2 thermodynamic properties within the quasi-harmonic approximation. The focus of the article is on the temperature dependencies of the heat capacity up to 1000 ℃ and values of enthalpy of formation, enthalpy, and entropy at 298,15 K, and their comparative analysis with the existing experimental data. The results show good general agreement with the published experimental data sets allowing to use them as arbitration of existing discrepancies. Increasing deviations of the heat capacity above the room temperature suggest that factors not included in the quasi-harmonic approximation, such as vibrational anharmonicity, may have a significant influence on the thermodynamics of 2H-MoSe2 in this temperature region. Considering the inconclusive high-temperature data from the experiment, the present results may be recommended as a satisfactory approximation until the appearance of more reliable experimental data or calculation results, taking into account more finite-temperature effects.
Suppressors of mRNA Decapping Defects Restore Growth Without Major Effects on mRNA Decay Rates or Abundance
Authors: Kim Minseon , van Hoof Ambro 
Published: October 2020

Abstract
Faithful degradation of mRNAs is a critical step in gene expression, and eukaryotes share a major conserved mRNA decay pathway. In this major pathway, the two rate-determining steps in mRNA degradation are the initial gradual removal of the poly(A) tail, followed by removal of the cap structure. Removal of the cap structure is carried out by the decapping enzyme, containing the Dcp2 catalytic subunit. Although the mechanism and regulation of mRNA decay is well understood, the consequences of defects in mRNA degradation are less clear. Dcp2 has been reported as either essential or nonessential. Here, we clarify that Dcp2 is not absolutely required for spore germination and extremely slow growth, but in practical terms it is impossible to continuously culture dcp2∆ under laboratory conditions without suppressors arising. We show that null mutations in at least three different genes are each sufficient to restore growth to a dcp2∆, of which kap123∆ and tl(gag)g∆ appear the most specific. We show that kap123∆ and tl(gag)g∆ suppress dcp2 by mechanisms that are different from each other and from previously isolated dcp2 suppressors. The suppression mechanism for tL(GAG)G is determined by the unique GAG anticodon of this tRNA, and thus likely by translation of some CUC or CUU codons. Unlike previously reported suppressors of decapping defects, these suppressors do not detectably restore decapping or mRNA decay to normal rates, but instead allow survival while only modestly affecting RNA homeostasis. These results provide important new insight into the importance of decapping, resolve previously conflicting publications about the essentiality of DCP2, provide the first phenotype for a tl(gag)g mutant, and show that multiple distinct mechanisms can bypass Dcp2 requirement.
RESPUESTA DE CREATINA QUINASA A UN EJERCICIO ANAEROBIO SUPRAMÁXIMO EN GENOTIPOS DE ACTN3
Authors: Güereca-Arvizuo J. , Ramos-Jiménez A. , Moreno-Brito V. , Cervantes-Borunda M. , Hernández-Torres R.P. 
Published: October 2020

El objetivo del presente estudio fue investigar las diferencias en la actividad de la enzima Creatina Quinasa (CK) en pre y post ejercicio anaerobio supramáximo (EASM) en portadores de los genotipos del gen de la alfa-actinina-3 (ACTN3). Se reclutaron 39 hombres sanos físicamente activos (18-35 años) y se sometieron a un EASM de 30 s (Wingate). El gen ACTN3 se determinó a partir del ADN de glóbulos blancos en sangre periférica y se evaluó la actividad de la CK en muestras sanguíneas en condiciones basales, a las 24 y 48 h post EASM. Los portadores del genotipo XX vs RR presentaron 1,4 veces menor actividad de CK en condiciones basales (p<0,05) y una mayor actividad de CK a las 24 h post ejercicio (p<0,05). Una serie de EASM fue capaz de causar un incremento significativo de la actividad de CK a las 24 h en los portadores del genotipo XX.
LA OBSERVACIÓN EN CONTEXTO DE LOS NIVELES DE ACCIÓN EN BALONMANO
Authors: Lasierra G. , Carreras D. , Montoya M. , Planas A. 
Published: October 2020

Esta investigación plantea como objetivo principal diseñar un instrumento de registro que permita describir y relacionar tres niveles de acción del balonmano (juego de equipo, juego grupal y juego individual), vinculándolos al contexto de competición y atendiendo a su eficacia. Siguiendo las directrices de la metodología observacional se opta por un sistema combinado de formatos de campo y sistema de categorías, utilizando un diseño de investigación de carácter ideográfico, puntual y multidimensional. Se utiliza como instrumento de registro el software Dartfish TeamPro V.4.5 para analizar siete partidos de categoría absoluta, y siete partidos de categoría infantil, generándose datos de tipo concurrente y de evento. Se aplican técnicas estadísticas descriptivas e inferenciales bivariadas para el análisis relacional de los datos. Destacamos los resultados que constatan la asociación entre sistemas de juego y procedimientos colectivos tanto ofensivos como defensivos, y la dificultad en establecer relaciones significativas entre el ataque y la defensa.
ANÁLISIS TÉCNICO-TÁCTICO OFENSIVO CON BALÓN DE LA SELECCIÓN ESPAÑOLA DE FÚTBOL SALA
Authors: Álvarez-Kurogi L. 
Published: October 2020

Los objetivos de este estudio fueron describir los fundamentos técnicos-tácticos ofensivos con balón de la selección española de fútbol sala, las superficies de contacto y las zonas del terreno de juego donde se inicia cada fundamento, así como examinar la relación asociativa entre dichos fundamentos y los otros dos criterios. Se empleó la metodología observacional. Predomina el pase y control del balón, así como el empeine, interior y planta del pie, además del inicio de los fundamentos en zonas del campo rival. Asimismo, destaca la realización significativamente mayor del control del balón con la planta del pie, manejo del balón combinando diferentes superficies de contacto, pase con el interior del pie, conducción con el empeine del pie, regate combinando distintas superficies de contacto y tiro también con el empeine. Por último, resalta la realización significativamente mayor del control y pase desde campo propio y regate y tiro desde campo rival.
Reproducción de <i>Polymita muscarum</i> y <i>Polymita venusta</i> (Stylommatophora: Helminthoglyptidae)
Authors: Bidart Liana , Femández Alejandro , Iglesias Caridad 
Published: October 2020

Se estudiaron algunos aspectos de la reproducción de Polymita muscarunm y Polymita venusta en condiciones de laboratorio y en poblaciones naturales de la provincia de Holguín durante el período comprendido entre septiembre de 1985 y mayo de 1990. Se encontró que la época de reproducción se extiende desde julio hasta diciembre en el laboratorio y desde julio a enero en la naturaleza. Se realiza una descripción de la conducta copulatoria y el desove. El tiempo entre cópula y oviposición es de 18 días para P. musearum y de 20 días para P. venusta, el tiempo de incubación fue de 8 días. El número de huevos por nido para P. muscarum fue de 84. 12 huevos y de 142.2 para P. venusta, con una tasa de natalidad de 52.65 % y 19.9 % respectivamente.