bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seroprevalence, risk factors and impact of Toxoplasma gondii infection on haematological parameters in the Ashanti region of Ghana: a cross-sectional study
Authors: Agordzo Samuel Kekeli , Badu Kingsley , Addo Mathew Glover , Owusu Christian Kwasi , Mutala Abdul-Hakim , Tweneboah Austine , Ackom Abbas Dawood , Ayisi-Boateng Nana Kwame 
Published: November 2019

Background: Toxoplasma gondii is an obligate, intracellular, apicomplexan parasite that causes toxoplasmosis. Although the global prevalence of toxoplasmosis has been estimated to be approximately 30%, there is limited seroprevalence data in Ghana, with a dearth of information on the impact of T. gondii on haematological parameters in exposed persons. Methods: Questionnaires were administered to 300 consenting individuals to obtain demographic information and assessment of their risk of exposure to T. gondii. Using anti-T. gondii IgG/IgM combo test kits, seropositivity to parasite-specific IgG and/or IgM was determined. A haematological analyser was used to measure haematological parameters. Results: The participants included 58 males and 242 females, and ranged in age from 6 months to 84 years, with a median age of 27 years. There was an overall seroprevalence of 50.3% (n=151), with 49.7% (n=149) of the study participants seropositive for IgG and 1% (n=3) testing positive for IgM. Furthermore, the observed seroprevalence among pregnant women was 56.4% (n=62). With regards to the different communities in which the hospitals were located, a seroprevalence of 55.6% was observed in the rural community, 50.6% in the peri-urban community and 47.1% in the urban community. The study identified cat ownership, contact with cat litter [RR (95% CI: 1.76 (1.23-2.53), 1.66 (1.03-2.67), 1.25(1.00-1.57)] and age (p<0.001) as risk factors for infection. Analyses of haematological data also revealed significant differences between the red blood cell counts (p=0.038) and mean corpuscular volumes (p=0.0007) of seropositive and seronegative study participants. Conclusions: About half of the study population, including a significant number of women of reproductive age carried antibodies against T. gondii, raising questions about the risk of congenital toxoplasmosis, as well as possible links to anaemia. We, therefore, recommend that screening for Toxoplasma gondii be included in the routine screening of pregnant women seeking antenatal care.
On the evaluation of research software: the CDUR procedure
Authors: Gomez-Diaz Teresa , Recio Tomas 
Published: November 2019

Background: Evaluation of the quality of research software is a challenging and relevant issue, still not sufficiently addressed by the scientific community. Methods: Our contribution begins by defining, precisely but widely enough, the notions of research software and of its authors followed by a study of the evaluation issues, as the basis for the proposition of a sound assessment protocol: the CDUR procedure. Results: CDUR comprises four steps introduced as follows: Citation, to deal with correct RS identification, Dissemination, to measure good dissemination practices, Use, devoted to the evaluation of usability aspects, and Research, to assess the impact of the scientific work. Conclusions: Some conclusions and recommendations are finally included. The evaluation of research is the keystone to boost the evolution of the Open Science policies and practices. It is as well our belief that research software evaluation is a fundamental step to induce better research software practices and, thus, a step towards more efficient science.
Incidence of postoperative delirium according to cognitive status, improved responsiveness and inflammatory response at elderly patients in urgent abdominal surgery
Authors: Demyter Inna , Gudz Dmytro , Vorotyntsev Sergey 
Published: November 2019

Background. Postoperative delirium (POD) is a clinical syndrome that is manifested in impaired consciousness and attention, perception, memory, thinking and psychomotor behavior after surgery. Methods. After passing the Bioethics Commission at Zaporizhzhya State Medical University and obtaining informed consent from patients, 30 elderly patients who underwent surgical interventions on the abdominal organs under urgent procedure were sequentially included in a single-center prospective study. Patients with a history of traumatic brain injury or stroke with neurological impairments in the form of sensory-motor aphasia and plegia were excluded from the study.Results .The study involved 30 patients (16 (53%) women and 14 (47%) men), aged 62 years to 92 years, grade III-IV ASA, who underwent urgent surgery for bowel tumors (n = 8), gallstone disease (n = 7), entrained inguinal and postoperative ventral hernias (n = 10), gastric or intestinal perforation (n = 5). Postoperative delirium occurred in 33% of patients. On the first day after surgery, the cognitive status of patients in the first group decreased by 1 point relative to the primary assessment (p = 0.88), when on the second postoperative day the indicator returned to baseline. Patients in the second group showed a sharp impairment of cognitive abilities in the postoperative period, associated with POD and a significant decrease in cognitive status at day 5 (p <0.05) compared with preoperative assessment. The level of inflammatory response of the body in the preoperative period is 1.5 times higher in patients with POD (p = 0.01). The correlation between leukocytosis level and POD revealed a moderately significant relationship between these indicators (rs = 0.45 at p <0.05).Conclusions. In 33% of urgent patients, abdominal surgery revealed postoperative delirium, which is reliably dependent on cognitive deficits for surgery and the level of systemic inflammation (p = 0.01). The level of patient wear does not significantly affect the incidence of POD.
Characterization of e-beam evaporated Ge, YbF3, ZnS, and LaF3 thin films for laser-oriented coatings
Authors: Amotchkina Tatiana , Trubetskov Michael , Hahner Daniel , Pervak Vladimir 
Published: November 2019

Thin films of Ge, ZnS,

Y
b
F

3

, and

L
a
F

3

produced using e-beam evaporation on ZnSe and Ge substrates were characterized in the range of 0.4–12 µm. It was found that the Sellmeier model provides the best fit for refractive indices of ZnSe substrate, ZnS, and

L
a
F

3

films; the Cauchy model provides the best fit for

Y
b
F

3

film. Optical constants of Ge substrate and Ge film as well as extinction coefficients of ZnS,

Y
b
F

3

,

L
a
F

3

, and ZnSe substrate are presented in the frame of a non-parametric model. For the extinction coefficient of ZnS, the exponential model is applicable. Stresses in Ge, ZnS,

Y
b
F

3

, and

L
a
F

3

were estimated equal to

(
−

50

)

M
P
a

,

(
−

400

)

M
P
a

, 140 MPa, and 380 MPa, respectively. The surface roughness does not exceed 5 nm for all films and substrates.
Performing citizenship illegally: The Nimis Groupe and political migrant theatre in Europe
Authors: Paire Roxane 
Published: November 2019

Abstract
The Nimis Groupe are an international theatre collective made up of six Belgian and six French actors. Roxane Paire interviewed them in 2015 while they were working on a play entitled Ceux que j'ai rencontrés ne m'ont peut-être pas vu (Those that I've met probably did not see me). This piece focused on the legal mechanisms of asylum in the European Union and was performed by actors from the company who performed onstage alongside some of the migrants who had informed the research for the play. This intervention discusses the ethical implications of the European members of the company working alongside migrants who were not at that point legally recognized as citizens.
KARAKTERISTIK DAN DAMPAK SIKLON TROPIS YANG TUMBUH DI SEKITAR WILAYAH INDONESIA
Authors: Surinati Dewi , Kusuma Dwi Ayu 
Published: November 2019

CHARACTERISTICS AND IMPACTS OF TROPICAL CYCLONES GROWING AROUND INDONESIAN TERRITORY. Tropical cyclone is a cyclonic originates from tropical oceans and driven principally by heat transfer from the ocean. Tropical cyclone is an atmospheric phenomenon characterized by the emergence of low air pressure that triggers the occurrence of strong winds due to the process of heat transfer from the equator to the latitude. This phenomenon can not be prevented, so that it has great potential to impact on the damage in the area it through. Tropical cyclones can be characterized through their life cycle, scale of power and how it impacts in the area it through. The Cempaka and Dahlia tropical cyclone occuring in 2017 greatly influenced territory of Indonesia. The effect of the cyclone causes extreme weather in Indonesia, especially in areas close to where cyclones are formed.
Artificial Intelligence for the Determination of a Management Strategy for Diminutive Colorectal Polyps: Hype, Hope, or Help
Authors: Cho Bum-Joo , Bang Chang Seok 
Published: November 2019

Abstract
Most colorectal polyps are diminutive, and malignant potential for these polyps is uncommon, especially for those in the rectosigmoid. However, many diminutive polyps are still being resected to determine whether these are adenomas or serrated/hyperplastic polyps. Resecting all the diminutive polyps is not cost-effective. Therefore, gastroenterologists have proposed optical diagnosis using image-enhanced endoscopy for polyp characterization. These technologies have achieved favorable outcomes, but are not widely available. Artificial intelligence has been used in clinical medicine to classify lesions. Here, artificial intelligence technology for the characterization of colorectal polyps is discussed in a decision-making context regarding diminutive colorectal polyps.
Constant sign and nodal solutions for superlinear double phase problems
Authors: Gasiński Leszek , Papageorgiou Nikolaos S. 
Published: November 2019

Abstract
We consider a double phase problems with unbalanced growth and a superlinear reaction, which need not satisfy the Ambrosetti–Rabinowitz condition.
Using variational tools and the Nehari method, we show that the Dirichlet problem has at least three nontrivial solutions, a positive solution, a negative solution and a nodal solution. The nodal solution has exactly two nodal domains.
Your data is gold – Data donation for better healthcare?
Authors: Strotbaum Veronika , Pobiruchin Monika , Schreiweis Björn , Wiesner Martin , Strahwald Brigitte 
Published: November 2019

Abstract
Today, medical data such as diagnoses, procedures, imaging reports and laboratory tests, are not only collected in context of primary research and clinical studies. In addition, citizens are tracking their daily steps, food intake, sport exercises, and disease symptoms via mobile phones and wearable devices. In this context, the topic of “data donation” is drawing increased attention in science, politics, ethics and practice. This paper provides insights into the status quo of personal data donation in Germany and from a global perspective. As this topic requires a consideration of several perspectives, potential benefits and related, multifaceted challenges for citizens, patients and researchers are discussed. This includes aspects such as data quality & accessibility, privacy and ethical considerations.
Digital health – Software as a medical device in focus of the medical device regulation (MDR)
Authors: Becker Kurt , Lipprandt Myriam , Röhrig Rainer , Neumuth Thomas 
Published: November 2019

Abstract
The Medical Device Directive (MDD) will be replaced on 26.05.2020 by the new Medical Device Regulation (MDR). The European Parliament wants to create a transparent, solid, predictable and sustainable legal framework. One of the major upcoming changes effects the perspective on software as a medical device. This paper describes the fundamental relationships between the policy framework and the challenges faced by manufacturers and operators of medical devices, in particular medical software and artificial intelligence (AI) systems, who need to verify compliance. To address this topic, we review and discuss the main implications of medical device regulations on software as a medical device and digital health applications along the MDR structure. Furthermore, we address practical limitations of the implementation, such as the availability of notified bodies and costs of the approval procedure.
Generalized multivariate Fink-type identity and some related results on time scales with applications
Authors: Hussain Sabir , Latif Muhammad Amer 
Published: November 2019

Abstract
Generalized Fink-type identity for multi-variables to an arbitrary
time scales is obtained, giving some multi-variate Ostrowski,
Iyengar and Grüss-type inequalities unifying the corresponding
continuous and discrete version. Some new applications to
generalized polynomials are also obtained.
Optical coherence tomography for non-destructive testing
Authors: Zechel Fabian , Kunze Rouwen , König Niels , Schmitt Robert Heinrich 
Published: November 2019

Abstract
In this review paper, conventional non-destructive testing (NDT) methods are briefly introduced and compared with selected examples for applications of optical coherence tomography (OCT) for NDT. The contactless, non-destructive and purely optical method enables multi-dimensional imaging for tomographic real-time evaluation in various fields of application. Depending on the material, penetration depths of several millimeters can be achieved, thus providing an attractive solution that can be used both as a stand-alone and as a process-integrated solution.
Validación y confiabilidad de un protocolo para tiempo de reacción simple con el instrumento MOY-ART 35600
Authors: Galvis Fajardo Carlos Arturo , Castro Jiménez Laura Elizabeth , Luque Aldana Nicolás 
Published: November 2019

Una dificultad con la medición del tiempo de reacción (TR) es que se define de diferentes formas y no permite una comparación entre diferentes poblaciones. Este es un estudio cuantitativo en donde se busca evaluar la confiabilidad del TR con el instrumento MOY-ART 35600. Participaron 24 estudiantes voluntarios (18- 26 años), que fueron aleatorizados en tres grupos, 1) 30 intentos consecutivos (30TR); 2) 120 intentos consecutivos (120TR); y 3) 120 intentos, divididos en bloques de 30 intentos con 4 minutos de descanso entre bloque (TR120d), La aplicación de los protocolos se realizó en tres diferentes momentos a los mismos participantes. En la primera toma se encontró en 30TR (M = 274,4ms; DS± 60.45ms), 120TR (M = 257,41ms; DS±45.52ms), 120TRd (M = 239,3 ms; DS±50ms). En la segunda toma se encontró en 30TR (M = 274.1 ms; DS±47.26ms), 120TR (M = 244.85; DS±46.06ms), 120TRd (M = 233.22ms; DS±39.07ms). Tercera toma se encontró en 30TR (M = 278.58 ms; DS± 66.17ms), 120TR (M = 239.69; DS± 36.08ms), 120TRd (M = 240.24ms; DS± 84.45s). Se encontró que el protocolo con mejores resultados en la aplicación, por consistencia en las medias, y por la menor varianza en el grupo fue el de 120TRd. Evidenciando que es mejor aplicar un protocolo con un número de intentos muy alto pero que tenga descansos, que son esenciales para evitar el agotamiento nervioso.
Estilos de apego parental y dependencia emocional en las relaciones románticas de una muestra de jóvenes universitarios en Colombia
Authors: Rocha Narvaez Brenda Liz , Umbarila Castiblanco Jaqueline , Meza Valencia Magda , Riveros Fabián Andrés 
Published: November 2019

El presente estudio tuvo como propósito identificar la relación entre los estilos de apego parental y la dependencia emocional en las relaciones románticas de un grupo de jóvenes universitarios en Colombia. Es un estudio cuantitativo de tipo descriptivo correlacional. La muestra a conveniencia fue de 500 estudiantes universitarios pertenecientes a 15 ciudades de Colombia, de la cual 34,2% fueron hombres y 65,8% mujeres entre los 18 y los 25 años. El cuestionario de recolección de datos estuvo conformado por 81 preguntas a partir de los siguientes instrumentos: datos sociodemográficos, Inventario de Apego con Padres y Pares modificado (IPPA modificado) y, Cuestionario de Dependencia Emocional (CDE). Se encuentra una correlación positiva entre los estilos de apego parental y la dependencia emocional en las relaciones románticas de los jóvenes que componen la muestra, así como una correlación positiva entre el nivel socioeconómico y la variable sexo en las manifestaciones de dependencia emocional dentro de la relación romántica.
Akirin Is Required for Muscle Function and Acts Through the TGF-β Sma/Mab Signaling Pathway inCaenorhabditis elegansDevelopment
Authors: Bowman Richard , Balukoff Nathan , Clemons Amy , Koury Emily , Ford Talitha , Baxi Kunal , Egydio de Carvalho Carlos , Smolikove Sarit 
Published: November 2019

AbstractAkirin, a conserved metazoan protein, functions in muscle development in flies and mice. However, this was only tested in the rodent and fly model systems. Akirin was shown to act with chromatin remodeling complexes in transcription and was established as a downstream target of the NFκB pathway. Here we show a role for Caenorhabditis elegans Akirin/AKIR-1 in the muscle and body length regulation through a different pathway. Akirin localizes to somatic tissues throughout the body of C. elegans, including muscle nuclei. In agreement with its role in other model systems, Akirin loss of function mutants exhibit defects in muscle development in the embryo, as well as defects in movement and maintenance of muscle integrity in the C. elegans adult. We also have determined that Akirin acts downstream of the TGF-β Sma/Mab signaling pathway in controlling body size. Moreover, we found that the loss of Akirin resulted in an increase in autophagy markers, similar to mutants in the TGF-β Sma/Mab signaling pathway. In contrast to what is known in rodent and fly models, C. elegans Akirin does not act with the SWI/SNF chromatin-remodeling complex, and is instead involved with the NuRD chromatin remodeling complex in both movement and regulation of body size. Our studies define a novel developmental role (body size) and a new pathway (TGF-β Sma/Mab) for Akirin function, and confirmed its evolutionarily conserved function in muscle development in a new organism.
Optimized Genetic Testing for Polledness in Multiple Breeds of Cattle
Authors: Randhawa Imtiaz A S , Burns Brian M , McGowan Michael R , Porto-Neto Laercio R , Hayes Ben J , Ferretti Ryan , Schutt Karen M , Lyons Russell E 
Published: November 2019

Abstract
Many breeds of modern cattle are naturally horned, and for sound husbandry management reasons the calves frequently undergo procedures to physically remove the horns by disbudding or dehorning. These procedures are however a welfare concern. Selective breeding for polledness – absence of horns – has been effective in some cattle breeds but not in others (Bos indicus genotypes) due in part to the complex genetics of horn phenotype. To address this problem different approaches to genetic testing which provide accurate early-in-life prediction of horn phenotype have been evaluated, initially using microsatellites (MSAT) and more recently single nucleotide polymorphism (SNP). A direct gene test is not effective given the genetic heterogeneity and large-sized sequence variants associated with polledness in different breeds. The current study investigated 39,943 animals of multiple breeds to assess the accuracy of available poll testing assays. While the standard SNP-based test was an improvement on the earlier MSAT haplotyping method, 1999 (9.69%) out of 20,636 animals tested with this SNP-based assay did not predict a genotype, most commonly associated with the Indicus-influenced breeds. The current study has developed an optimized poll gene test that resolved the vast majority of these 1999 unresolved animals, while the predicted genotypes of those previously resolved remained unchanged. Hence the optimized poll test successfully predicted a genotype in 99.96% of samples assessed. We demonstrated that a robust set of 5 SNPs can effectively determine PC and PF alleles and eliminate the ambiguous and undetermined results of poll gene testing previously identified as an issue in cattle.
Quality assurance agencies: Creating a conducive environment for academic integrity
Authors: Garwe Evelyn C. 
Published: November 2019

Academic integrity is a key measure of the quality, efficiency and competitiveness of higher education systems. This article explores how a quality assurance agency can foster a conducive environment for academic quality and integrity. A self-study methodology was used, with a focus on the insights and experiences of the Zimbabwe Council for Higher Education over a 10-year period. The findings show that by assuming an innovative and transformational leadership role in instilling a culture of self-evaluation, as well as maintaining its own integrity, an external quality assurance agency can improve academic integrity. The article adds value to the existing knowledge by advancing the higher education ecosystem approach as an integrity-based panacea and conducive way to induce integrity to flow from all players as opposed to the use of heavy-handed regulatory approaches.
Significance:

This article highlights the importance of academic integrity and situates quality assurance agencies as playing a central role in fostering academic integrity.
KREATYWNOŚĆ W ŚWIETLE TEORII UCZENIA SIĘ MUZYKI E. E. GORDONA
Authors: Bonna Beata 
Published: November 2019

<p>W artykule zaprezentowano najważniejsze założenia teorii uczenia się muzyki E. E. Gordona dotyczące rozwijania kreatywności poprzez improwizację, która jest najdoskonalszym przejawem myślenia muzycznego. Skupiono się w nim na opisaniu pojęć związanych z kreatywnością, twórczością oraz aktywnością twórczą. Szczególną uwagę poświęcono<br />charakterystyce twórczości i improwizacji muzycznej, rodzajów improwizacji oraz metod jej kształtowania, jak również sposobów pomiaru i oceny. W polskiej rzeczywistości edukacyjnej twórczość i improwizacja nie zajmują należnego im miejsca. Wskazania wynikające z założeń<br />gordonowskiej teorii uczenia się muzyki mogą stanowić ważny punkt odniesienia do ich szerszego uwzględnienia w systemie edukacji muzycznej w polsce.</p>
Warsztat twórczy jako metoda edukacji artystycznej na wydziałach nieartystycznych.
Authors: Cabak Marcin Emil 
Published: November 2019

<p>W artykule podjęto problematykę zastosowania warsztatu twórczego jako metody dydaktycznej w edukacji artystycznej na wydziałach nieartystycznych. W pierwszej części analizowane jest na podstawie literatury pojęcie warsztatu twórczego jego geneza, historia,<br />umiejscowieni w przestrzeni sztuki, oraz dylematy związane z zastosowaniem go w warunkach wydziałów innych niż artystyczne. drugą część stanowi opis przeprowadzonych w warunkach nieartystycznej uczelni wyższej działań warsztatowych. Trzecia zawiera wnioski. W części<br />czwartej prezentowane są przykładowe wytwory powstałe w czasie warsztatu.</p>