bluuebunny/crossref_metadata_2025_split huggingface dataset:
BIM Integration Possibilities in Different Study Cycles of Architecture Study Programme
Authors: Mlinkauskienė Aušra , Christensen Per , Finocchiaro Luca , Lobaccaro Gabriele 
Published: April 2020

European countries are developing or implementing policies that promote or require the use of information modelling in the architecture, engineering, construction and manufacture sectors. The integration of Building Information Modelling (BIM) to these sectors includes social, economic, political, legal and other aspects. This is why the implementation of BIM requires an integrated and broad approach that includes not only the BIM implementation and development strategy in designing companies but also in the field of education and professional training. The article discusses the potential of integrating BIM in different study programs and the possibilities of international cooperation in interdisciplinary BIM projects. The different levels of BIM will be explored in connection to different curricula. Particular attention is paid to the compatibility and applicability of design and innovative technology solutions using BIM methodology and the development of co-operation between higher education institutions in the Nordic region [1].
The aim of this paper is to carry out a comparative analysis and present the integration model of Building Information Modeling (BIM) into the Architecture programmes in different study cycles based on the example of Nordic countries.
Objectives:

To provide BIM use opportunities in 3 years Bachelor level based on Engineeering architecture study programme of VIA University College;
To provide BIM use opportunities in 5 years Integrated studies based on Architecture studies programme of Kaunas University of Technology;
To provide BIM use opportunities in the 2 years Master of Science program in Sustainable Architecture at the Norwegian University of Science and Technology;
To perform comparative analysis between different countries and different study cycles;
To provide a possible model for integration of the international BIM project in different study cycles.
Research and Development of the New Progressive Construction Press Machines
Authors: Šooš Ľubomír 
Published: April 2020

Throughout the world in the last two decades, solid noble biofuels produced on the basis of wood and agricultural biomass have been widely used. Many European Union countries have enacted legislation for solid noble biofuels oriented primarily to energy carriers manufactured from wood raw materials. The production of noble biofuels is a fitting direction for the recovery of biomass and other energy wastes. Fuel in the twenty-first century must, in addition to environmental and economic criteria, fulfil the criterion of high comfort and safety in its combustion. Modern energy carriers must have uniform size, density, moisture and shape. One of the most progressive means of waste recovery is the compaction of particulate matter into different shapes and sizes. The technologies of transforming biomass into biofuels with the required properties are compacting, briquetting and pelleting. I am working on a research of compaction technologies and the development of compacting machine design at the Institute of Production Systems, Environmental Technology and Quality Management of the Faculty of Mechanical Engineering of STU in Bratislava for more than 26 years. In its scientific research activity, the definition of equations describing the dynamic process of compaction, experimental tests of the compaction process, design and testing of new press machine were undertaken. Over the stated period, we have designed and developed several machines that are today in serial production. Chief among these is the BL 55–280 briquetting press, the DZ 240 disintegrating machine, the KUDO 2009 mobile unit for treatment of wood waste, the TR 200 solid material separator, the PLG 150 round pelleting press, the ZBL-2-860 double-screw briquetting press or the RCM 650 ring compacting machine. We have submitted over 53 patents and industrial models. The aim of this chapter is to describe the new original and progressive designs of these press machines.
A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of Escherichia coli by a multiplex polymerase chain reaction
Authors: Shi Yaoqiang , Li Chao , Yang Guangying , Xia Xueshan , Mao Xiaoqin , Fang Yue , Zhang A-Mei , Song Yuzhu 
Published: April 2020

Background
Antibiotics are highly effective drugs used in the treatment of infectious diseases. Aminoglycoside antibiotics are one of the most common antibiotics in the treatment of bacterial infections. However, the development of drug resistance against those medicines is becoming a serious concern.

Aim
This study aimed to develop an efficient, rapid, accurate, and sensitive detection method that is applicable for routine clinical use.

Methods
Escherichia coli was used as a model organism to develop a rapid, accurate, and reliable multiplex polymerase chain reaction (M-PCR) for the detection of four aminoglycoside modifying enzyme (AME) resistance genes Aac(6′)-Ib, Aac(3)-II, Ant(3″)-Ia, and Aph(3′)-Ia. M-PCR was used to detect the distribution of AME resistance genes in 237 clinical strains of E. coli. The results were verified by simplex polymerase chain reaction (S-PCR).

Results
Results of M-PCR and S-PCR showed that the detection rates of Aac(6′)-Ib, Aac(3)-II, Ant(3″)-Ia, and Aph(3′)-Ia were 32.7%, 59.2%, 23.5%, and 16.8%, respectively, in 237 clinical strains of E. coli. Compared with the traditional methods for detection and identification, the rapid and accurate M-PCR detection method was established to detect AME drug resistance genes. This technique can be used for the clinical detection as well as the surveillance and monitoring of the spread of those specific antibiotic resistance genes.
Human Health Risk Assessment of Heavy Metals in Onion Bulbs Cultivated in Katsina State, North West Nigeria
Authors: Yaradua A.I. , Alhassan A. J. , Nasir A. , Matazu S. S. , Usman A. , Idi A. , Muhammad I. U. , Yaro S. A. , Nasir R. 
Published: April 2020

Vegetable fields in Katsina State are increasingly being loaded with heavy metals through various pollution sources such as agricultural activities mining and traffic. Onion bulb samples from the three senatorial zones that constitute to make up Katsina state in the North West of Nigeria were collected and the concentrations of seven heavy metals (Pb, Cd, Cr, Fe, Zn, Mn and Ni) in all the samples were determined by atomic absorption spectrometry. The health risk assessment methods developed by the United States Environmental Protection Agency (US EPA) were employed to explore the potential health hazards of heavy metals in the samples on the children and adult population. The highest mean concentration (mg/kg) was observed for Fe, followed by Pb, Zn and Mn. While Cd has the lowest concentration with the heavy metals Cr and Ni being below detection level (BDL). Overall hazard index (Hi) for the heavy metals were within the safety limit. The overall cancer risk to the adults based on pseudo-total metal concentrations exceeded the target value, mainly contributed by Pb. Mn and Zn were the primary heavy metals posing non-cancer risks while Pb caused the greatest cancer risk. It was concluded that consumption of the onion samples from Katsina State may contribute to the population cancer burden.
Residents’ Perception of Ecotourism in Ratargul Freshwater Swamp Forest of Bangladesh
Authors: Mree Chisol Luis , Das Sanjoy , Ray Tusher Kumer , Chowdhury Pinaki , Saha Narayan 
Published: April 2020

Aims: The study aims at finding out the perceived economic, environmental and socio-cultural impacts of ecotourism by residents who live near the Ratargul freshwater swamp forest.
Study Design: The study is qualitative and empirical which focuses on the residents’ attitudes towards the economic, environmental and socio-cultural changes due to ecotourism.
Place and Duration of Study: The study was conducted in the villages near the Ratargul freshwater swamp forest located in Gowainghat Upazila of Sylhet District of Bangladesh. The study period was from November 2014 to February 2015.
Methodology: A total of 301 respondents were interviewed from the residents using a formulated questionnaire consisting of nine demographic variables and thirty-five impact items classified into economic, environmental and socio-cultural categories. A five-point rating scale was incorporated into each impact item for both belief and evaluation components. The sampling method was arbitrary (non-probability sampling) but without preconceived bias.
Results: The study shows the impact items regarding economic and socio-cultural aspects secured higher ranks by possessing higher mean values. Contrarily, items associated with the environmental aspect possessed lower mean values. These findings denote that residents favored both the economic and socio-cultural impacts of tourism as they positively perceived both impacts, whereas the environmental impact was least favored by the residents. Besides, it was also found that resident’s attitudes towards ecotourism vary with the variations in income, occupation, and gender.
Conclusion: The study concluded that residents acknowledge economic and socio-cultural benefits conveyed by ecotourism without sacrificing environmental and aesthetic aspects. Further studies are recommended to find out the trends of ecotourism and its impacts on residents and the forest.
Impact of Industrial Effluent Discharge on the Physico-chemical Properties of Aleto Stream, Eleme, Rivers State, Nigeria
Authors: Gbarakoro S. L. , Gbarakoro T. N. , Eebu W. L. 
Published: April 2020

Aim: This research work aimed to determine the impact of industrial effluent discharge on the physicochemical properties of Aleto Stream, Eleme and Rivers State.
Study Design: Random sampling technique was applied in this study. The study area was divided into three sites; upstream, downstream all of Aleto Stream and Agbonchia Stream which serves for the control experiment. Water samples for eleven physical and six chemical parameters were collected in a Completely Randomized Design.
Place and Duration of Study: This study was carried out on Aleto and Agbonchia streams at Eleme, Rivers State, Nigeria from 2017 to 2018.
Methodology: Two samples were collected; one sample at the Aleto stream where the industrial effluent is being channelled into the stream and the other sample was collected from Agbonchia stream, which was used as a control. In the Aleto Stream, sampling was made at two points; point A (upstream) point B (downstream) and each of these points had their Physico-chemical properties tested while only one sample was collected from the Agbonchia Stream. Physico-chemical properties were analyzed in the samples using pH meter for pH, Turbidity meter for turbidity, Conductivity meter for electrical conductivity, phosphate by colourimetric method, total dissolved solids (TDS) and total suspended solids (TSS) by gravimetric method, biochemical oxygen demand (BOD) and chemical oxygen demand (COD) by standard method, chloride, alkalinity, dissolved oxygen (DO), calcium hardness, total hardness by titrimetric method, colour, odour and taste by sensory method.
Results: Results obtained on the Physico-chemical properties had varying concentrations of Temperature, Total hardness, Chloride, Alkalinity, DO and Phosphate that were within world health organization (24) and Federal Ministry of Environment (1991) permissible limits on both upstream and downstream with values ranging from 29.0-23.7oC, 360-125 mg/l, 120-100 mg/l, 36-30 mg/l, 4.9-4.4 mg/l, 1.92-1.2 mg/l respectively while Electrical conductivity, Turbidity, TSS, TDS, Calcium hardness, COD, BOD, Colour, Taste and Odour were above permissible limits on both upstream and downstream with values ranging from 1660-1700 mg/l, 83-112NTU, 82-80 mg/l, 910-914 mg/l, 1590-1900 mg/l, 100-165 mg/l, 4.36-3.88 mg/l respectively. The pH values ranged from 9.0-6.3 mg/l showing a result on the upstream to be alkaline while the downstream was slightly acidic. The increase in the above parameters above their permissible limits is as a result of the impact of industrial effluent discharges drained into the stream. This indicates that the stream is unfit for both human and aquatic inmates.
Conclusion: Therefore, proper management of this effluent should be ensured and an acute test with lethal concentration (LC50) as the endpoint is recommended to determine the degree of toxicity of the effluent waste.
Transient Slug Flow Modelling of Subsea Riser Flowline System
Authors: Moses Akin-Taylor Akinbowale , Briggs Tobinson A. 
Published: April 2020

A gas-water system slug velocity was modelled with slug flow like a train of slug units streaming through a steel flowline riser of roughness 0.025 was modelled, the flowline was 2700 m, and the riser was 100 m with a diameter of 0.254 m, with each slug unit having a liquid slug of 100 m and its gas bubble of 200 m. Presumptuously the liquid phase was not compressible; that is, no gas was entrapped in the liquid; there is also no liquid was trapped within the gas. Unsteady state flow was modelled as a mass-spring system with damping. Liquid phase represented the mass, whereas the gas represented the spring and damping as the force of friction that acts on the fluids in motion by the wall. A quasi-steady-state model having a slug velocity of 4 ms-1 was used to simplify the numerical correlations and algorithm and to relate with outcomes of the unsteady state model. Outputs from both models show that pressure and rate vary sinusoidally at fixed points in the system. Both models are unconcealed that the velocity of every slug unit was most at the end of flowline to the separator. The result from the transient state model is complex for weighing up with other results from the literature. This procedure was as a product of over-simplification owing to some assumptions made. Also, simultaneous solutions to the differential equations were solved with hand. It is determined that quasi-steady-state outputs are more reliable than the unsteady state model for flowlines that are not situated on heaving surfaces because the model is less complicated and follows the predictable trend.
Content Validation of Basic Education Certificate Examination Questions in Basic Science in Adamawa State, Nigeria
Authors: Buba Maryamu Atari , Kojigili Stephen Tizhe 
Published: April 2020

The study assessed the content validation of Basic Education Certificate Examination (BECE) questions in Basic Science set by Adamawa State Educational Resource Centre (ERC), Yola, Nigeria. This was to determine the representativeness of the topics and their levels of the cognitive domain in the Junior Secondary School Basic Science curriculum in the Basic Education Certificate Examination in Basic Science question papers from 2013 to 2017. Document analysis research design was adopted for the study. The population of the study comprised all past Basic Education Certificate Examination questions in Basic Science. The research instrument used for the data collection was a designed checklist along table of specification. A pilot study was conducted and a reliability index of 0.86 was obtained using Cronbach alpha analysis. Three research questions were raised with two hypotheses tested at 0. 05 level of significance. The result of the findingp=0.000 revealed that there is no significant difference between the topics in the Basic Science curriculum and those examined in the Basic Education Certificate Examination questions in Basic Science. Again, the result 0.675 showed that there is significant difference between the weights assigned to the various levels of cognitive domain in the Basic Science curriculum and those weights assigned to them in Basic Education Certificate Examination Basic Science question papers. Based on the findings, it was recommended that re-training, workshops, conferences and seminars should be organized for Basic Science teachers and external examiners regularly to update their knowledge on test construction.
Longitudinal trajectories of behavior change in a national sample of patients seeking eating‐disorder treatment
Authors: Chapa Danielle A. N. , Hagan Kelsey E. , Forbush Kelsie T. , Clark Kelsey E. , Tregarten Jenna P. , Argue Stuart 
Published: April 2020

AbstractObjectiveRapid response to treatment, indicated by substantial decreases in eating‐disorder (ED) symptoms within the first 4–6 weeks of treatment, is the most reliable predictor of treatment outcomes for EDs. However, there is limited research evaluating short‐term longitudinal trajectories of ED symptoms during treatment. Thus, it is difficult to know which aspects of ED psychopathology are slow or fast to change. The purpose of this study was to elucidate three‐month trajectories of ED psychopathology during treatment and test whether ED diagnosis influenced the direction and rate of change.MethodParticipants were Recovery Record users seeking treatment for an ED (N = 4,568; 86.8% female). Participants completed the Eating Pathology Symptoms Inventory once per month for 3 months.ResultsLatent growth curve models indicated that ED diagnosis influenced the rate of ED behavior change. Anorexia nervosa was associated with faster reductions in cognitive restraint, excessive exercise, restricting, yet slower reductions in body dissatisfaction, and binge eating. Bulimia nervosa was associated with faster reductions in binge eating, cognitive restraint, excessive exercise, and purging. Binge‐eating disorder was associated with faster reductions in body dissatisfaction and binge eating, yet slower reductions in restricting.ConclusionsOur results have implications for future research by providing initial information about the direction and rate of ED change over the course of treatment. If clinicians and researchers know which ED symptoms are slow to change, on average, across diagnostic groups, treatment protocols could be adjusted to target slow changing symptoms more quickly, and therefore improve ED treatment outcomes.
Sustained release of stromal cell–derived factor‐1 alpha from silk fibroin microfiber promotes urethral reconstruction in rabbits
Authors: Liu Yang , Huang Li , Yuan Wei , Zhang Dongliang , Gu Yubo , Huang Jianwen , Murphy Sean , Ali Mohamed , Zhang Yaopeng , Song Lujie 
Published: April 2020

AbstractWe developed a stromal cell–derived factor‐1 alpha (SDF‐1α)‐aligned silk fibroin (SF)/three‐dimensional porous bladder acellular matrix graft (3D‐BAMG) composite scaffold for long‐section ventral urethral regeneration and repair in vivo. SDF‐1α‐aligned SF microfiber/3D‐BAMG, aligned SF microfiber/3D‐BAMG, and nonaligned SF microfiber/3D‐BAMG scaffolds were prepared using electrostatic spinning and wet processing. Adipose‐derived stem cell (ADSC) and bone marrow stromal cell (BMSC) migration was assessed in the SDF‐1α‐loaded scaffolds. Sustained SDF‐1α release in vitro and vivo was analyzed using enzyme‐linked immunosorbent assay (ELISA) and western blotting, respectively. The scaffolds were used to repair a 1.5 × 1 cm2 ventral urethral defect in male rabbits in vivo. General observation and retrograde urinary tract contrast assessment were used to examine urethral lumen patency and continuity at 1 and 3 months post‐surgery. Postoperative rehabilitation was evaluated using histological detection. The composite scaffolds sustained SDF‐1α release for over 16 days in vitro. SDF‐1α‐aligned SF nanofiber promoted regeneration of urethral mucosa, submucosal smooth muscles, and microvasculature, increased cellular proliferation, and reduced collagen deposition. SDF‐1α expression was increased in reconstructed urethra at 3 months post‐surgery in SDF‐1α‐aligned SF group. SDF‐1α‐aligned SF microfiber/3D‐BAMG scaffolds may be used to repair and reconstruct long urethral defects because they accelerate urethral regeneration.
Early behavioral and developmental interventions in ADNP‐syndrome: A case report of SWI/SNF‐related neurodevelopmental syndrome
Authors: Shillington Amelle , Pedapati Ernest , Hopkin Robert , Suhrie Kristen 
Published: April 2020

AbstractBackgroundAutism spectrum disorder (ASD) affects approximately one in 59 children. Variants in the activity‐dependent neuroprotector homeobox ADNP (OMIM #611386) gene may be one of the most common single‐gene causes of syndromic ASD. Most patients diagnosed with ADNP syndrome have ASD as a comorbidity, and all patients have mild‐to‐severe intellectual disability.Methods/Case ReportWe present a case report of a patient diagnosed with ADNP syndrome at 2.5 years of age. The patient has many of the key features of the syndrome, including ASD, global developmental delay, behavioral problems, congenital heart defect, early tooth eruption, and vision problems. The patient's initial presentation included congenital diaphragmatic hernia (CDH), which has not been previously reported in this condition.ResultsThe patient exhibited frequent behavioral outbursts and was initiated on antipsychotic medication with near‐complete resolution of symptoms allowing her to engage more fully in early intervention therapies leading to progress in language acquisition.ConclusionThis short report provides guidance for antipsychotic medication dosing to improve early intervention outcomes. This is the first report of CDH in this syndrome.
Nonreportable rates and cell‐free DNA profiles in noninvasive prenatal testing among women with heparin treatment
Authors: Nakamura Noriyuki , Sasaki Aiko , Mikami Masashi , Nishiyama Miyuki , Akaishi Rina , Wada Seiji , Ozawa Nobuaki , Sago Haruhiko 
Published: April 2020

AbstractObjectiveTo evaluate the “nonreportable” rate in patients treated with heparin and to determine the effect of heparin on the results of noninvasive prenatal testing (NIPT).MethodThis was a single‐center retrospective study of NIPT. The “nonreportable” rate of NIPT was evaluated according to presence or absence of heparin treatment. After excluding true‐positive cases, a matched cohort study evaluating Z‐scores, GC bias, and cell‐free DNA (cfDNA) profiles was performed to investigate the effect of heparin on NIPT results.ResultsOverall, 2651 singleton pregnancies with available clinical information were evaluated; 23 mothers were treated with heparin. The nonreportable rate was much higher among patients treated with heparin than among those who were not (8.70% vs 0.15%). In the matched cohort study, the Z‐scores for chromosomes 13, 18, and 21, and GC bias were significantly higher in the heparin group than in the matched control group. Based on cfDNA library electrophoresis data, the proportion of short‐sized cfDNA was higher in the heparin group.ConclusionHeparin use increased the nonreportable rate of NIPT results by borderline Z‐scores, possibly caused by the increased proportions of shorter and GC‐rich cfDNA fragments. This information will be helpful for prenatal genetic counseling for patients requiring heparin treatment.
Architectural control of polystyrene physical properties using branched anionic polymerization initiated at ambient temperature
Authors: Alhilfi Tamara , Chambon Pierre , Rannard Steve P. 
Published: April 2020

AbstractAmbient temperature‐initiated anionic polymerization has generated branched polystyrenes of varying molecular weights and architectures by inclusion of a distyryl branching comonomer into a conventional sec‐Butylithium‐initiated polymerization of styrene. Primary chain length control within the branched polymers, and restriction of the branching points to varying segments of the primary chains, led to variations of glass transition temperature with no direct correlation to the branched polymer molecular weight but a strong relationship to the length of individual chains comprising the branched macromolecules.