bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arqueologia, museus e identidade cultural
Authors: Wichers Camila Azevedo de Moraes 
Published: July 2020

Este artigo traz inquietações acerca da relação entre arqueologia, museus e identidade cultural, à luz dos questionamentos queer. Museus e Arqueologia, como instituições modernas, têm reforçado uma identidade pautada na hetero-cis-normatividade e na branquitude. Por sua vez, a perspectiva queer interpela qualquer noção fixa de identidade, prezando pela fluidez. Nesse sentido, busco recuperar aspectos da relação entre arqueologia musealizada e identidade cultural, a partir de alguns modelos institucionais, passando à crítica queer de como os mesmos lidam com os processos identitários. Defendo, então, a compreensão das identidades a partir do conceito diferença, trazendo exemplos da ressignificação da arqueologia musealizada.
ANALISIS EVALUASI PEMBELAJARAN GURU TERSERTIFIKASI DI SMA JAKARTA PUSAT
Authors: Samadi  
Published: July 2020

Abstrak
The purpose of this study was to analyze aspects of the evaluation of learning in high school schools in Central Jakarta. The method used in this research is quantitative descriptive through the analysis of learning tools used in daily teaching and learning activities. The sample of this study consisted of 19 geography teachers who had been certified at SMAN 25, SMAN 4, and SMAN 68, SMAN 35, SMAN 7, SMAN 24, SMAN 30, SMAN 5, SMAN 1, and SMAN 10, and private schools namely SMA Santa Theresia, Paskalis High School, Taman Madya 1 and 5 High School, and Petojo IPPI High School. The analysis technique in this study uses descriptive methods in the form of matrix analysis. The results of the study indicate that the teacher learning tools that have been certified, especially in the evaluation component of learning are as follows: (1) Not the work of the teacher itself, namely the results of giving or the effects of selecting specifically for teaching materials and student worksheets, and (2) Not fully developed.
Keywords: Learning evaluation analysis, Certified teacher, Central Jakarta High School

Abstrak

Tujuan penelitian ini adalah menganalisis aspek-aspe evaluasi pembelajaran di sekolah-sekolah SMA di Jakarta Pusat. Metode yang digunakan dalam penelitian ini adalah deskriptif kuantitatif melalui analisis perangkat pembelajaran yang digunakan dalam kegiatan belajar mengajar sehari-hari. Sampel penelitian ini terdiri dari 19 orang guru geografi yang telah disertifikasi di SMAN 25, SMAN 4, dan SMAN 68, SMAN 35, SMAN 7, SMAN 24, SMAN 30, SMAN 5, SMAN 1, dan SMAN 10, serta sekolah swasta yaitu SMA Santa Theresia, SMA Paskalis, SMA Taman Madya 1 dan 5, dan SMA IPPI Petojo. Teknik analisis dalam penelitian ini menggunakan metode deskriptif dalam bentuk analisis matriks.
Hasil penelitian menunjukkan bahwa perangkat pembelajaran guru yang sudah disertifikasi khususnya pada komponen evaluasi pembelajaran adalah sebagai berikut : (1) Bukan hasil karya guru itu sendiri, yaitu hasil pemberian atau hasil dari memilih khusus untuk bahan ajar dan lembar kerja siswa, serta (2) Tidak dikembangkan secara maksimal.
Kata kunci : Analisis evaluasi pembelajaran, Guru tersertifikasi, SMA Jakarta Pusat
MAPPING CONDITION BAHAN AJAR DAN LKS PENDIDIKAN JASMANI DI PONDOK PESANTREN DKI JAKARTA
Authors: Sudewo Tomi Ari 
Published: July 2020

Abstrak

Tujuan penelitian adalah untuk memperoleh pemahaman yang mendalam khususnya terhadap pelaksanaan bahan ajar dan LKS pendidikan jasmani di Pondok Pesantren di DKI Jakarta. Pendekatan dalam penelitian ini menggunakan pendekatan kualitatif dengan dengan menggunakan metode deskriptif. Populasi penelitian adalah lembaga pendidikan Pondok Pesantren yang berada di lima wilayah Provinsi DKI Jakarta yaitu Pondok Pesantren Al Wathoniyah, Al Itqon, Al Hamid, Al Jauhariyah, Al Qalam, An Nur, An Nuriyah, As Shiddiqiyah, Darunnajah, Miftahul Ulum, Persis 69, PTDI Al Qesmaniyah, Al Hidayah, Asy-Syawarifiyah Malaka. Sampel penelitian diperoleh melalui teknik sampel bertujuan (purposive sample). Sumber data dalam penelitian ini adalah guru dan kepala sekolah terkait Pelaksanaan Pendidikan Jasmani di pondok pesantren di DKI Jakarta. Analisis data penelitian menggunakan statistik deskriptif.
Hasil penelitian menunjukkan bahwa komponen assessment / penilaian bahan ajar dan LKS; dua komponen ini merupakan peluang bagi ponpes, tetapi pada kenyataannya kurang dikembangkan, sehingga cukup mendatangkan masalah bagi pelaksanaan pendidikan jasmani di Pondok Pesantren di DKI Jakarta.
Kata kunci : Assessment bahan ajar, assessment LKS, Pendidikan jasmani, Pondok Pesantren, DKI Jakarta
High BANCR expression is associated with worse prognosis in human malignant carcinomas: An updated systematic review and meta-analysis
Authors: Fang Shi xu , Liu Zhou , Guo Qiang , Chen Cheng , Ke Xi xian , Gang Xu 
Published: July 2020

Abstract
Background: BRAF-activated noncoding RNA (BANCR) is aberrantly expressed in various tumor tissues and has been confirmed to function as a tumor suppressor or oncogene in many types of cancers. Considering the conflicting results and insufficient sampling, a meta-analysis was performed to explore the prognostic value of BANCR in various carcinomas. Methods: A comprehensive literature search of PubMed, Web of Science, EMBASE, Cochrane Library and the China National Knowledge Infrastructure (CNKI) was conducted to collect relevant articles. Results: The pooled results showed a strong relationship between high BANCR expression and poor overall survival (OS) (HR (hazard ratio) =1.60, 95% confidence interval (CI): 1.19-2.15, P =0.002) and recurrence-free survival (RFS) (HR=1.53, 95% CI: 1.27-1.85, P <0.00001). In addition, high BANCR expression predicted advanced tumor stage (OR (odds ratio) =2.39, 95% CI: 1.26-4.53, P =0.008), presence of lymph node metastasis (OR=2.03, 95% CI: 1.08-3.83, P =0.03), positive distant metastasis (OR=3.08, 95% CI: 1.92-4.96, P <0.00001) and larger tumor sizes (OR=1.63, 95% CI: 1.09-2.46, P =0.02). However, no associations were found for smoking status (OR=1.01, 95% CI: 0.65-1.56, P =0.98), age (OR=0.88, 95% CI: 0.71-1.09, P =0.236) and sex (OR=0.91, 95% CI: 0.72-1.16, P =0.469). The sensitivity analysis of OS showed that the results of each publication were almost consistent with the combined results, and the merged results have high robustness and reliability. Conclusions: The results showed that elevated BANCR expression was associated with unfavorable prognosis for most cancer patients, and BANCR could serve as a promising therapeutic target and independent prognostic predictor in most of cancer types.
Sjogren’s Syndrome is associated with higher healthcare utilization after primary hip, but not primary knee arthroplasty: A U.S. cohort study
Authors: Singh Jasvinder A , Cleveland John D. 
Published: July 2020

Abstract
Objective: To assess whether Sjogren’s Syndrome (SS) is associated with outcomes after total knee or hip arthroplasty (TKA/THA). Methods: We used the 1998-2014 U.S. National Inpatient Sample data. We performed multivariable-adjusted logistic regression analyses to assess the association of SS with healthcare utilization (hospital charges, length of hospital stay, discharge to non-home setting), and in-hospital complications (implant infection, revision, transfusion, mortality), controlling for important covariates and confounders. In sensitivity analyses, we additionally adjusted the main models for hospital location/teaching status, bed size, and region . Results: We examined 4,116,485 primary THAs and 8,127,282 primary TKAs performed from 1998-2014; 12,772 (0.2%) primary TKAs and 6,222 (0.2%) primary THAs were done in people with SS. In multivariable-adjusted models, SS was associated with a statistically significant higher odds ratio (OR; 95% confidence interval (CI)) of discharge to a rehabilitation/inpatient facility post-THA, 1.13 (1.00, 1.28), but not post-TKA, 0.93 (0.86, 1.02). We noted no differences in the length of hospital stay or hospital charges. SS was associated with significantly higher adjusted odds of in-hospital transfusion post-THA, 1.37 (1.22, 1.55) and post-TKA, 1.21 (1.10, 1.34). No significant differences by SS diagnosis were seen in hospital stay, hospital charges implant infection, implant revision or mortality rates. Conclusions: People with SS had higher transfusion rate post-TKA/THA, and higher rate of discharge to non-home setting post-THA. The lack of association of SS with post-arthroplasty complications should reassure patients, surgeons and policy-makers about the utility of TKA/THA in people with SS undergoing these procedures.
Prevalence and determinants of undernutrition among under-five children residing in urban slums and rural area, Maharashtra, India: a community-based cross-sectional study
Authors: Murarkar Sujata Kapil , Gothankar Jayashree Sachin , Doke Prakash , Pore Prasad , Lalwani Sanjay , Dhumale Girish , Quraishi Sanjay , Patil Reshma Sudhir , Waghachavare Vivek , Dhobale Randhir , Rasote Kirti , Palkar Sonali , Malshe Nandini 
Published: July 2020

Abstract
Background Undernutrition among under five children in India is a major public health problem.Despite India’s growth in the economy, the child mortality rate due to undernutrition is still high in both urban and rural areas.Studies that focus on urban slums are scarce. Hence the present study was carried out to assess the prevalence and determinants of undernutrition in children under five in Maharashtra, India.Methods A community-based cross-sectional study was conducted in 16 randomly selected clusters in two districts of Maharashtra state, India. Data were collected through house to house survey by interviewing mothers of under five children. Total 2929 mothers and their 3,671 under five children were covered. Multivariate logistic regression analysis was carried out to identify the determinants of child nutritional status seperately in urban and rural areas. Results The mean age of the children was 2.38years (±SD 1.365) and mean age of mothers was 24.25(± SD6.37) years.Overall prevalence of stunting among children under five was 45.9 %, wasting was 17.1% and 35.4% children were underweight.Prevalence of wasting, stunting and underweight were more seen in an urban slum than a rural area.In the rural areas exclusive breast feeding(p<0.001) and acute diarrhea (p=0.001)in children underfive were associated with wasting, children with birth order 2 or less than 2 were more affected by stunting and exclusive breast feeding (p<0.05) and low maternal education were associated with underweight.Whereas in the urban slums exclusive breast feeding(p<0.05) was associated with wasting, sex of the child (p<0.05) and type of family(p<0.05)were associated with stunting,and low income of the family(p<0.05) was associated with underweight.Conclusion Factors like sex of the child, birth order,exclusive breast feeding ,economic status of the family, type of family,acute diarrhea and maternal education have influence on nutritional status of the child. Improvement of maternal education will improve the nutritional status of the child. Strategies are needed to improve the economic status of the community.The trial registration-This article is part of baseline data of the project, hence not related to trial registration. After baseline data principal investigator had done trial registration retrospectively.
Untargeted metabolomics reveals the effect of lovastatin on steroid-induced necrosis of the femoral head in rabbits
Authors: Ren Xiangnan , Shao Zixing , Fan Wu , Wang Zixuan , Chen Kaiyun , Yu Xuefeng 
Published: July 2020

Abstract
PURPOSE

Lovastatin is an important medicine and it shows a significant effect against glucocorticoid-induced necrosis of the femoral head. This study aimed to investigate the effect of lovastatin on preventing necrosis of the femoral head of by serum metabolomics strategy.

METHODS

Adult healthy adult Japanese white rabbits were divided into three groups: control group, model group and drug group. The pathologic changes of femoral head were assessed with magnetic resonance imaging and microscope. Metabolomics based on UHPLC-MS/MS was used to analyze the collected serum sample. Data were analyzed using principal component analysis (PCA), partial least squares-discriminate analysis (PLS-DA) and orthogonal partial least squares-discriminant analysis (OPLS-DA). All potential metabolites were identified by comparing with HMDB database, metlin database, lipid maps and chemspider database.

RESULTS

11 potential biomarkers were noted and identified as potential biomarkers. The change of biomarkers suggested that lovastatin on preventing necrosis of the femoral head may affect glycerophospholipid metabolism, linoleic acid metabolism, sphingolipid metabolism, alpha-Linolenic acid metabolism, pyrimidine metabolism, arachidonic acid metabolism.

CONCLUSION

The study suggested that lovastatin could prevent the glucocorticoid-induced necrosis of the femoral head of rabbits. The possible reasons were closely associated with adjusting the lipid metabolism, inhibiting adipogenesis and delaying the osteocyte apoptosis.
Person-Centred, Occupation-Based Intervention Program Supported with Problem-Solving Therapy for Type 2 Diabetes: A Randomized Controlled Trial
Authors: Ağce Zeynep Bahadır , Ekici Gamze 
Published: July 2020

Abstract
Background: Individuals with diabetes mellitus have difficulty solving problems in meaningful occupations and have similar difficulties with self-care regimens. We examined the effects of an occupation-based intervention supported with problem-solving therapy in individuals with type 2 diabetes mellitus on participation in and satisfaction with meaningful occupations, diabetes-related psychosocial self-efficacy, preferred coping strategies and individual well-being. Methods: This study was planned as a single-blind, randomised controlled study with a 3-month follow-up involving sixty-seven adults with type 2 diabetes. The Canadian Occupational Performance Measure, Diabetes Empowerment Scale, Brief COPE and five-item World Health Organisation Well-Being Index were used. This programme included evaluations, diabetes education, and problem-solving therapy. The intervention was conducted for six weeks, and each weekly session lasted approximately 60 minutes. Differences between groups were analysed using the Mann-Whitney U test, and the Friedman test was used to calculate group-time interaction differences (i.e., baseline, after six weeks and after three months). Results: All participants identified the most significant occupational performance problems in self-care as personal care. Significant improvement was reported in the intervention group compared to the control group regarding participation in meaningful occupation, satisfaction with performance, psychosocial self-efficacy, and well-being results (p<0.001) after the programme and three months of follow-up. Participant use of effective coping strategies, active coping and acceptance strategies, and self-efficacy, as revealed by the results, suggested improvement in favour of the intervention group (p<0.05). Conclusions: Occupation-based problem-solving therapy encourages participation in meaningful occupations and improves psychosocial self-efficacy, effective coping styles, and well-being in patients with type 2 diabetes mellitus. Problem-solving therapies that incorporate individuals’ priorities via meaningful occupation can be used to lead to a meaningful and quality life for individuals with type 2 diabetes mellitus.
Immediate effects on cervical mobility and spiratory flow, after bilateral manipulation of first rib, in non-specific chronic neck pain: study protocol for a randomized controlled trial
Authors: Gonzalez-Gerez Juan Jose , Utrera Carlos Bernal , Anarte Ernesto , Rodriguez-Blanco Cleofas 
Published: July 2020

Abstract
Background: Numerous publications have showed the biomechanical influence of thoracic spine on cervical spine. Recently, some authors have pointed out the role of other physiological systems in this relationship, what have been calle interdependence regional model. It has been studies that interventions applied over thoracic spine have a neurophysiological influence on cervical spine and respiratory system. Our study evaluates the influence of bilateral manipulative technique of first rib on pain and pulmonary function in subjects with chronic non-specific neck pain.Methods: The immediate changes produced by bilateral direct manipulation (HVLA) of first rib in subjects with non-specific chronic neck pain will be studied. The sample will be randomly divided into two groups, experimental and placebo. As dependent variables of the study, we will measure the peak expiratory flow and cervical rom. Findings will be analyzed statistically considering a 5% significance level (p ≤ 0.05)Discussion: Our study aims to provide knowledge about the influence of bilateral manipulative technique of first rib in pain and pulmonary capacity in subjects with non-specific chronic neck pain. The efficacy of this technique may entail an easy access and low cost strategy in patients with pain and a reduction in pulmonary function. Trial registration Brazilian Clinical Trial Registry, RBR-4dsvfy. Registered on 17 March 2020.
Minimally Invasive Versus open AbdominoThoracic Esophagectomy (MIVATE) - study protocol for a randomized controlled trial DRKS00016773
Authors: Nickel Felix , Probst Pascal , Studier-Fischer Alexander , Nienhüser Henrik , Pauly Jana , Kowalewski Karl-Friedrich , Weiterer Sebastian , Knebel Philipp , Diener Markus K. , Weigand Markus A. , Büchler Markus W. , Schmidt Thomas , Müller-Stich Beat Peter 
Published: July 2020

Abstract
Background: The only curative treatment for most esophageal cancers is radical esophagectomy. Minimally invasive esophagectomy (MIE) aims to reduce postoperative morbidity, but is not yet widely established. Linear stapled anastomosis is a promising technique for MIE because it is quite feasible even without robotic assistance. Aim of the present study is to compare total MIE with linear stapled anastomosis to open esophagectomy (OE) with circular stapled anastomosis with special regard to postoperative morbidity in an expertise-based randomized controlled trial (RCT). Methods/design: This superiority RCT compares MIE with linear stapled anastomosis (intervention) to OE with circular stapled anastomosis (control) for Ivor-Lewis esophagectomy. It was initiated in February 2019 and recruitment is expected to last for 3 years. For inclusion, patients must be 18 years of age or more with a resectable primary malignancy in the distal esophagus. Participants with tumor localizations above the azygos vein, metastasis or infiltration into adjacent tissue will be excluded. In an expertise-based approach the allocated treatment will only be carried out by the single most experienced surgeon of the surgical center for each respective technique. The sample size was calculated with 20 participants per group for the primary endpoint postoperative morbidity according to comprehensive complication index (CCI) within 30 postoperative days. Secondary endpoints include anastomotic insufficiency, pulmonary complications, other intra- and postoperative outcome parameters such as estimated blood loss, operative time, length of stay, short-term oncologic endpoints, adherence to a standardized fast-track protocol, postoperative pain, and postoperative recovery (QoR-15). Quality of life (SF-36, CAT EORTC QLQ-C30, CAT EORTC QLQ-OES18) and oncological outcomes are evaluated with 60 months follow-up. Discussion: MIVATE is the first RCT to compare OE with circular stapled anastomosis to total MIE with linear stapled anastomosis exclusively for intrathoracic anastomosis. The expertise-based approach limits bias due to heterogeneity of surgical expertise. The use of a dedicated fast-track protocol in both OE and MIE will shed light on the role of the access strategy alone in this setting. The findings of this study will serve to define which approach has the best perioperative outcome for patients requiring esophagectomy. Trial registration: German Clinical Trials Register DRKS00016773. Registered on February 18th, 2019.
Whole exome sequencing reveals a combination of rare high and low penetrance variants that correlates with familial breast cancer relative risk
Authors: rekaya Mariem Ben , Hamdi Yosr , Benna Houda El , Mejri Nessrine , Jaidane Olfa , Ayari Jihene , Nasr Sonia Ben , Dallali Hamza , Messaoud Olfa , Meddeb Rym , Mighri Najah , Boujemaa Maroua , Boubaker Mohamed Samir , Haddaoui Abderazek , Mrad Ridha , Boussen Hamouda , Abdelhak Sonia , Labidi Soumaya 
Published: July 2020

Abstract
Background: Genetic risk factors of breast cancer are very heterogeneous and complex. They vary according to the familial relative risk, the age of cancer diagnosis of the index case and the age of the affected relatives.Objectives: We aimed to investigate and identify simultaneously all rare pathogenic and common variants in unrelated BC cases with different relative risk ratios for breast cancer and evaluate the contribution of these variants in genetic susceptibility to breast cancer.Patients and Methods: All frequent mutations in BRCA genes previously identified in Tunisia have been excluded by Sanger sequencing in 42 women affected with high family risk having at least 3 cancer affected related individuals. Two unrelated cases having two different family histories (in terms of different numbers of affected first-degree relatives and young age onset) have been selected for whole exome sequencing. The first family is composed of three sisters F1.1, F1.2 and F1.3 affected at 46, 50, and 32 years old, respectively. The second has only two breast cancer cases, F2.2 and F2.4, affected at late age 61 and 70 years old, respectively, in addition to other 5 members affected by different kinds of cancer. Selected high risk variants were confirmed and segregation analysis was performed using Sanger sequencing. Results and discussion: For F1.1 case, we identified a pathogenic frame-shift loss of function variant in BRCA2 p.Val1283Lysfs. For F2.2 we identified a pathogenic rare variant in OGG1, p.Arg46Gln that co-segregates with a rare non sense variant in BRCA2 p.K3326X, only in the breast cancer affected cases. Moreover, F2.2 patient has 9 other common low penetrant variants in different loci known to represent independently minor, but cumulatively significant, increased risk for breast cancer.Conclusion: Family history and the young age at onset for patient F1.1 correlate with the presence of a rare high penetrant variant (p.Val1283Lysfs) in BRCA2 gene. However, the late age at onset and the less severe phenotype for patient F2.2 are probably the consequence of the presence of a pathogenic variant p.Arg46Gln in OGG1 gene that co-segregate with a low penetrant variant Lys3326X in BRCA2 only in breast cancer cases.