bluuebunny/crossref_metadata_2025_split huggingface dataset:
Removal of hexavalent chromium by hyporheic zone sediments in an urbanized estuary
Authors: Jung Hun Bok , Severini Jake , Hall Emaje 
Published: October 2020

Abstract
More than 2 million tons of chromium ore processing residue (COPR) waste was disposed of in Hudson County of New Jersey, which was known as the center of the production of chromate in the 20th century. The Cr(VI) removal experiments were conducted with the hyporheic zone (HZ) sediments collected along the shore of an urbanized estuary located in and near Hudson County to investigate the natural remediation of Cr(VI). Fine-grained and organic-rich Passaic River sediments showed the highest removal capacity for Cr(VI), whereas the lowest removal of Cr(VI) occurred in coarse-grained and organic-poor sediments from Newark Bay. In general, Cr(VI) removal increased with higher amounts of sediment organic matter, sulfur, and silt and clay fractions, as well as lower pH conditions. The removal of hexavalent chromium in organic-rich sediments is attributed mainly to the reduction of Cr(VI) to Cr(III), resulting in less reversible immobilization of Cr(VI), while reversible adsorption could also remove Cr(VI). The results suggest that the organic-rich, fine-grained HZ sediments can act as a natural reactive barrier for the remediation of Cr(VI) transport from subsurface to surface water in the estuary. Further research is needed to understand the long-term mobility of Cr along the urban estuary.
Application of Aloe vera mucilage as bioflocculant for the treatment of textile wastewater: process optimization
Authors: Ashwini Prabhakar Shende , Ojha Nupur , Das Nilanjana 
Published: October 2020

Abstract
Aloe vera is an important commodity plant which has been traditionally used for the treatment of various diseases. This study investigated the use of extracted bioflocculant from Aloe vera for the treatment of textile wastewater. The bioflocculant was extracted, purified and characterized using GC-MS, FTIR, SEM, AFM, EDX and XRD analysis. It was mainly composed of carbohydrate (19.5%) and protein (6.0%). Box-Behnken design (BBD), using 3 level-3 variables, was employed to enhance the decolorization process by optimizing the effect of various factors. A significant enhancement from 62.50 ± 0.1 to 82.01 ± 0.8% in decolorization of wastewater was observed under optimized conditions viz. bioflocculant dosage (60 mg/L), pH (5.0) and contact time (180 min). A quadratic polynomial model was adequate beside the actual statistics at an R2 value of 0.99 for the response decolorization % and was in good agreement with the predicted value (82.01 ± 0.1%) obtained by the RSM model. The results of the present investigation demonstrated that Aloe vera mucilage can serve as a promising bioflocculant with high removal efficiency for solids, colour and dye from wastewater. To the best of our information, this is the first report on the use of Aloe vera mucilage as a natural bioflocculant for the treatment of dye-bearing wastewater.
Pedagogos não docentes nos Institutos Federais de Educação, tensionando os processos de identificação
Authors: De Alencar Silva Silvana , Maria de Arruda Monteiro Filomena 
Published: October 2020

A atuação do Pedagogo nos Institutos Federais de Educação (IFs) concorre na produção de processos de identificação atravessados por narrativas que tentam definir o que é ser Pedagogo nos IFs. Portanto, almejou-se compreender como as pesquisas discutem esses processos, seus impactos e desafios. Metodologicamente, escolheu-se a orientação pela abordagem qualitativa e pela pesquisa do tipo bibliográfica. Para tal, foram realizados levantamentos de teses e de dissertações na Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). Considerou-se que as investigações tentaram regular processos de identificação pela compreensão de identidades fixas, como algo a ser encontrado com vistas aos anseios do que se espera do Pedagogo. Foi proposto que processos de identificação sejam entendidos como parte do desenvolvimento profissional do Pedagogo, superando assim entendimentos compartimentados que dissociam experiências pessoais e profissionais do ser Pedagogo nos IFs permeado por culturas institucionais e políticas oficiais de governo situadas em determinado tempo e lugar.
The Binding of Remdesivir to SARS-CoV-2 RNA-Dependent RNA Polymerase May Pave The Way Towards the Design of Potential Drugs for COVID-19 Treatment
Authors: Agoni Clement , Soliman Mahmoud E.S. 
Published: October 2020

Aim:
We seek to provide an understanding of the binding mechanism of Remdesivir, as well
as structural and conformational implications on SARS-CoV-2 virus RNA-dependent RNA polymerase
upon its binding and identify its crucial pharmacophoric moieties.

Background:
The coronavirus disease of 2019 (COVID-19) pandemic had infected over a million
people, with 65,000 deaths as of the first quarter of 2020. The current limitation of effective treatment
options with no approved vaccine or targeted therapeutics for the treatment of COVID-19 has posed
serious global health threats. This has necessitated several drug and vaccine development efforts across
the globe. To date, the farthest in the drug development pipeline is Remdesivir.

Objectives:
We performed the molecular dynamics simulation, quantified the energy contributions of
binding site residues using per-residue energy decomposition calculations, and subsequently generated
a pharmacophore model for the identification of potential SARS-CoV-2 virus RNA-dependent RNA
polymerase inhibitors.

Methods:
Integrative molecular dynamics simulations and thermodynamic calculations coupled with
advanced post-molecular dynamics analysis techniques were employed.

Results:
Our analysis showed that the modulatory activity of Remdesivir is characterized by an extensive
array of high-affinity and consistent molecular interactions with specific active site residues that
anchor Remdemsivir within the binding pocket for efficient binding. These residues are ASP452,
THR456, ARG555, THR556, VAL557, ARG624, THR680, SER681, and SER682. Results also
showed that Remdesivir binding induces minimal individual amino acid perturbations, subtly interferes
with deviations of C-α atoms, and restricts the systematic transition of SARS-CoV-2 RNA-dependent
RNA polymerase from the “buried” hydrophobic region to the “surface-exposed” hydrophilic region.
We also mapped a pharmacophore model based on the observed high-affinity interactions with SARSCoV-
2 virus RNA-dependent RNA polymerase, which showcased the crucial functional moieties of
Remdesivir and was subsequently employed for virtual screening.

Conclusion:
The structural insights and the optimized pharmacophoric model provided would augment the design of improved analogs of Remdesivir that could expand treatment options for COVID-19.
The Use of Small Electronic Devices and Health: Feasibility of Interventions for a Forthcoming Crossover Design
Authors: Larsen Lisbeth Hoekjaer , Lauritzen Maja Hedegaard , Gangstad Sirin Wilhelmsen , Kjaer Troels Wesenberg 
Published: October 2020

Background
Modern lifestyle is heavily affected by technology such as smartphones, tablets, and other small computers; yet it remains unclear how our health and well-being are affected by the heavy use of these devices.

Objective
This feasibility study aims to test two different interventions of an experimental protocol for a forthcoming large-scale community-based study and get estimates of parameters for sample size calculation. The aim of the large-scale study is to investigate the effect of (1) a wearable tracking device on aerobic capacity (VO2max/kg) and the effect of (2) restricting media use on total sleep time.

Methods
Twenty healthy participants were included and equipped with a wrist-worn device tracking physical activity and sleep. Participants were allocated to either a physical activity group, which was instructed to use the wrist-worn device to support exercise, or a sleep silent group, which was instructed to remove or switch off all electronic devices in the bedroom (except the wrist-worn tracking device). The intervention lasted approximately 4 weeks. Data collected included blood pressure, submaximal cycle ergometer test, self-reported technology use, and compliance of using the wearable tracking device.

Results
All participants wore the wearable tracking device 95.8% (SD 4.4%) of the time. Participants in the physical activity group increased aerobic capacity from 30.38 (SD 8.98) to 32.1 (SD 8.71) mL/kg/min (t=–2.31, P=.046) and decreased their systolic blood pressure from 126.5 (SD 15.8) mm Hg to 121.8 (SD 11.7) mm Hg (t=2.72, P=.02). The sleep silent group prolonged their time offline before bedtime from 18.1 (SD 19.4) minutes to 27.2 (SD 17.3) minutes (t=–2.94, P=.02).

Conclusions
The two interventions are feasible to conduct. Participants were willing to wear the tracking device on their wrist and restrict all media use in their bedroom and thereby reduce bedtime technology use. Our results also suggest that tracking physical activity using a wearable device is accompanied by noteworthy health benefits. We outline necessary adjustments for a forthcoming large-scale study.
Future Mobile Device Usage, Requirements, and Expectations of Physicians in German University Hospitals: Web-Based Survey
Authors: Maassen Oliver , Fritsch Sebastian , Gantner Julia , Deffge Saskia , Kunze Julian , Marx Gernot , Bickenbach Johannes 
Published: October 2020

Background
The use of mobile devices in hospital care constantly increases. However, smartphones and tablets have not yet widely become official working equipment in medical care. Meanwhile, the parallel use of private and official devices in hospitals is common. Medical staff use smartphones and tablets in a growing number of ways. This mixture of devices and how they can be used is a challenge to persons in charge of defining strategies and rules for the usage of mobile devices in hospital care.

Objective
Therefore, we aimed to examine the status quo of physicians’ mobile device usage and concrete requirements and their future expectations of how mobile devices can be used.

Methods
We performed a web-based survey among physicians in 8 German university hospitals from June to October 2019. The online survey was forwarded by hospital management personnel to physicians from all departments involved in patient care at the local sites.

Results
A total of 303 physicians from almost all medical fields and work experience levels completed the web-based survey. The majority regarded a tablet (211/303, 69.6%) and a smartphone (177/303, 58.4%) as the ideal devices for their operational area. In practice, physicians are still predominantly using desktop computers during their worktime (mean percentage of worktime spent on a desktop computer: 56.8%; smartphone: 12.8%; tablet: 3.6%). Today, physicians use mobile devices for basic tasks such as oral (171/303, 56.4%) and written (118/303, 38.9%) communication and to look up dosages, diagnoses, and guidelines (194/303, 64.0%). Respondents are also willing to use mobile devices for more advanced applications such as an early warning system (224/303, 73.9%) and mobile electronic health records (211/303, 69.6%). We found a significant association between the technical affinity and the preference of device in medical care (χs2=53.84, P<.001) showing that with increasing self-reported technical affinity, the preference for smartphones and tablets increases compared to desktop computers.

Conclusions
Physicians in German university hospitals have a high technical affinity and positive attitude toward the widespread implementation of mobile devices in clinical care. They are willing to use official mobile devices in clinical practice for basic and advanced mobile health uses. Thus, the reason for the low usage is not a lack of willingness of the potential users. Challenges that hinder the wider adoption of mobile devices might be regulatory, financial and organizational issues, and missing interoperability standards of clinical information systems, but also a shortage of areas of application in which workflows are adapted for (small) mobile devices.
Conectores de oposição: reflexões e propostas para o ensino
Authors: Pauliukonis Maria Aparecida Lino 
Published: October 2020

Estudo reflexivo e produtivo dos conectores de oposição em português, com o objetivo de sensibilizar os alunos interpretantes para a importância de seu papel semântico-argumentativo e pragmático em diferentes gêneros textuais. Tal enfoque possibilita oferecer uma visão discursiva dos conectores em língua portuguesa, o que pode contribuir para uma melhora significativa do processo de leitura e de produção textual.
A PERSONAGEM-MEMÓRIA E A EMERGÊNCIA DO ‘SER’ NA POÉTICA DE MIA COUTO
Authors: Vivian Ilse Maria da Rosa 
Published: October 2020

O presente artigo tem por objetivo observar as imagens de identidades formuladas pela literatura contemporânea a partir da construção narrativa que sustenta uma abordagem dinâmica da memória e um de seus constituintes primordiais para a elaboração do ser, a imaginação. Por essa via, realiza-se a leitura de Terra sonâmbula e de Um rio chamado tempo, uma casa chamada terra, ambos romances do escritor moçambicano Mia Couto. O trabalho enquadra-se, assim, no conjunto de reflexões que põe em relação à construção da personagem no romance contemporâneo a problemática da representação do sujeito, das estruturas e conjunturas que pontuam a relação do ser com o tempo e que compõem um universo de seres marcados pela alteridade. A abordagem da personagem, sob essa perspectiva, só pode acontecer pela hermenêutica exigida pela práxis narrativa, ou seja, a partir da situacionalidade originária do homem ao longo do percurso de reconhecimento de si mesmo, no seu universo pessoal, social e histórico.
OS MISTÉRIOS DO OLHAR DE ORFEU – HISTORICIDADE, METÁFORA E LITERATURA
Authors: Pinto Aline Magalhaes 
Published: October 2020

O crítico, ensaísta e romancista Maurice Blanchot explorou o fenômeno literário ao longo de sua obra mantendo como horizonte o reconhecimento da condição radicalmente póstuma da escrita e a inquietude que essa condição imprime ao escritor. Sua obra, fragmentária, esteve sempre atenta à relação entre a finitude - como experiência antropológica fundamental e como evento que evidencia a duração da vida humana, isso é, sua relação com o tempo - e a arte da escrita. Partindo desse ponto, propomos um estudo da imagem da morte em “Le regard d’Orphée”, ensaio de Maurice Blanchot. Esse ensaio apresenta-se como uma fascinante encenação da metáfora da morte e uma profunda meditação sobre a possibilidade da arte literária no imediato pós-guerra, tempo em que a aflição e o desamparo modernos se aguçam. Nossa intenção é desvendar a historicidade embutida da imagem da morte nesse ensaio de Blanchot.
Legally protected cultural goods and bankruptcy proceedings
Authors: Adamus Rafał 
Published: October 2020

This paper deals with general problems of legal aims of bankruptcy proceedings in connection with the aims of heritage protection – issues built by completely different systems of values. Bankruptcy is designed for protecting pecuniary interest of a limited group of people, while cultural heritage is protected for present and future generations, despite its current commercial significance. In the global environment, bankruptcy of a cultural goods owner usually has a cross-border range but national bankruptcy legislations and laws devoted to heritage protection differ in very serious aspects. For this reason the paper is not limited to any concrete legal order. There are discussed some important universal issues: limits for a trustee in managing cultural goods which are a part of bankruptcy estate, legal status of cultural goods excluded from bankruptcy estate, consequences of bankruptcy sale in the case of lack of bankrupt’s ownership title.
CARACTERÍSTICAS GERIÁTRICAS Y ABANDONO FAMILIAR DEL ADULTO MAYOR EN EL ASILO DE ANCIANOS DE CHICLAYO, 2018
Authors: Cobeñas Velásquez Doris Raquel , Gálvez Díaz Norma del Carmen 
Published: October 2020

El presente trabajo de investigación tuvo como objetivo Determinar la relación que existe entre las características geriátricas y abandono familiar del adulto mayor en el asilo de ancianos en Chiclayo, 2018. Fue de tipo cuantitativo no experimental. La muestra estuvo constituida por 75 adultos mayores. El criterio de inclusión fue: Adultos mayores con edades comprendidas entre los 65 y 85 años. Las bases teóricas se sustentan en Virginia Henderson Mendoza Díez. Roldán Monzón, Macia Torres, Murillo Fernández. La recolección de datos se realizó mediante la aplicación de encuesta y la observación, validada por 3 expertos. Los resultados fueron: que el 66.7% de adultos mayores tienen una edad de 80 a más años. Así mismo que el 58.7% son de género masculino y el 41.3% femenino. Al indagar sobre su grado de instrucción el 38.7% tiene estudios superiores. Se encontró que el 64% de los ancianos no tienen hijos profesionales, el 42.7% no tiene hijos. Frente al abandono familiar de los adultos mayores internados en el asilo de ancianos manifiestan que los tipos de abandono son: Emocional (69%), Económico (75%), Social (72%) y Rechazo (67%). La relación que existente entre las características geriátricas y el abandono familiar existe relación con: edad, religión, profesión u oficio, grado de instrucción, n° hijos profesionales y n° hijos. Para identificar la relación que existente entre el entorno familiar y el abandono familiar se encuentran relacionadas estadísticamente. Se concluye que existe relación con las características geriátrica ya abandono familiar en el adulto mayor.
PERCEPCIÓN DE LOS SÍNTOMAS DESAGRADABLES POR LA PERSONA HEMODIALIZADA. ANÁLISIS A LA LUZ DE LA TEORÍA DE ELIZABETH LENZ.
Authors: Marrufo Díaz Claudia Cristina 
Published: October 2020

La Enfermedad Renal Crónica (ERC) es un problema creciente a nivel mundial que afecta la vida y salud de millones de personas. Por ello es considerada como una de las principales causas de morbimortalidad y demanda un tratamiento sustitutivo. Dentro del cual está considerada la hemodiálisis, siendo un proceso que consiste en filtrar la sangre del paciente a través de la máquina de diálisis, atravesando un filtro de limpieza y volviendo de nuevo al paciente; generando así múltiples cambios sobre las personas que se someten a ella. En este contexto se realizó el estudio de investigación «Percepción de los síntomas desagradables por la persona hemodializada. Análisis a la luz de la teoría de Elizabeth Lenz.», que tuvo como objetivo: identificar, analizar y comprender la percepción de los síntomas desagradables por la persona hemodializada. El marco teórico estuvo sustentado por la Teoría de Síntomas Desagradables (TOUS) de Elizabeth Lenz. La investigación fue cualitativa con abordaje de estudio de caso; el instrumento de recolección de datos fue la entrevista semiestructurada. Los sujetos de investigación fueron 17 pacientes en Hemodiálisis del Centro del Riñón del Norte, delimitando el número por saturación. Se obtuvieron 3 categorías y 5 subcategorías: Intensidad individual de los síntomas desagradables de la terapia sustitutiva con la hemodiálisis. Afrontando y aceptando el tratamiento dialítico. Reconociendo el apoyo del entorno social. Asimismo, se respetaron los principios éticos y los criterios de cientificidad.
ESTRATEGIA ORGANIZACIONAL PARA MEJORAR LA PLANIFICACIÓN DEL TRABAJO DE LA EMPRESA AGROINDUSTRIAL POMALCA S.A.A
Authors: Aranda Arrellano Paola Karina , Cabrera Cabrera Xiomara 
Published: October 2020

La investigación aborda los resultados de una tesis de maestría. Revela insuficiencias en la planificación del trabajo y la planeación estratégica de la empresa agroindustrial Pomalca S.A.A para lo cual se definió el problema científico: Deficiente estructuración del proceso empresarial para el abastecimiento de insumos y materiales de la empresa, limita la planificación del trabajo. Por lo que, en el estudio teórico se profundizo en el proceso organizacional desde una gestión que potenciara la relación de la cultura organizacional de una empresa privada, a partir de la sistematización de las políticas de la organización empresarial. Se plantea como objetivo: Elaborar una estrategia organizacional para mejorar la planificación del trabajo. Se Fundamentó teóricamente el proceso organizacional y su gestión; se determinaron las tendencias históricas del proceso organizacional y su gestión, definiendo indicadores y etapas. Se caracterizó el estado actual de la gestión del proceso organizacional en los directivos y trabajadores de la empresa azucarera para lo cual se aplicó encuesta a colaboradores. Se realizó un análisis FODA de la Empresa agro industrial durante 2017 en base a fortalezas, oportunidades y amenazas del macro entorno económico. Se elaboró una estrategia organizacional, definiéndose etapas; áreas estratégicas y objetivos estratégicos con acciones a cumplimentar a corto, mediano y largo plazo. Se valoró la pertinencia científico-metodológica del aporte práctico mediante criterio de expertos con una validez de MUY BUENA y se realizó taller de socialización. Se utilizaron métodos teóricos, empíricos y estadísticos
ESTRATEGIA OPERATIVA BASADA EN LEAN MANUFACTURING PARA OPTIMIZAR LOS PROCESOS PRODUCTIVOS EN LA ELABORACIÓN DE MUEBLES EN FABRICACIONES LEONCITO CHICLAYO
Authors: Olivera Clavo Grimaldina , Tuesta Torres Edgar Roland , Mendiburu Rojas Augusto Franklin 
Published: October 2020

La elaboración de una Estrategia Operativa basada en herramientas Lean Manufacturing para la empresa Fabricaciones Leoncito S.A.C. permite mejorar los procesos productivos en la elaboración de muebles de melanina. Para tal propósito se realizaron evaluaciones del comportamiento del comercio y distribución de muebles a nivel internacional, nacional y local. En la evaluación de la información sobre de los procesos productivos, distribución y venta, se identifican oportunidades de mejora para la compañía. Se aplicó un diagnóstico para valorar las insuficiencias desde donde emerge el problema de investigación. En las oportunidades de mejora se identificaron herramientas que aseguraran las actividades. Los formatos fueron evaluados por Ingenieros con experiencia en procesos de producción de muebles de la misma empresa, arrojando un puntaje alto la estrategia. La aplicación del aporte se enfocó en dar solución a la merma de la melanina, esta estrategia fue reutilizar las retacerías en productos pequeños como: repisas, mesas de centro, percheros, maquetas para exhibir otros productos, lo que ayuda al área de Marketing, impulsando las ventas y dando valor agregado a los productos con contribución al medio ambiente.Palabras clave: Lean Manufacturing, procesos productivos, estrategia operativa basada en herramientas Lean Manufacturing