bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medical Malfunction: How Health Administrators can Become More Receptive to the LGBT Community
Authors: Murphy Anthony 
Published: September 2020

What companies have begun to see over the past few years is the slow destruction of the metaphorical closet the Lesbian, Gay, Bisexual, and Transgender (LGBT) community has been confined to for the past century. Now that the federal government has taken a proactive stance against discrimination in the workplace based on sexual orientation and gender identity, it will be up to health administrators to implement their own policies that will assist employees and management in being more receptive to the needs of their LGBT workers. Here, you will find several procedures and strategies that can be put into practice by hospitals and clinics that make for a much more sensitive work environment. Combining these strategies into the culture of the workplace will increase productivity and decrease employee conflict and ostracizing among LGBT employees.
The Effect of Increased Intracellular Calcium on the Localization of the Catabolic Subunit of Telomerase, hTERT, in HeLa Cells
Authors: Diffendall Gretchen M. , Resendes Dr. Karen K. 
Published: September 2020

In cancer cells, telomeres are constantly repaired by telomerase allowing them to avoid reaching a critical length where the cell becomes senescent. Overtime, aerobic respiration in the mitochondria can create an increase in intracellular reactive oxygen species (ROS) that causes telomerase reverse transcriptase (hTERT), the catabolic subunit of telomerase, to exit the nucleus. Without hTERT in the nucleus, telomerase cannot function to repair telomere ends, inducing senescence. One effect of increased ROS production is the activation of calcium channels leading to an increase in intracellular calcium. We attempted to mimic this ROS induced increase in intracellular calcium levels by administering 0.5uM of Thapsigargin to HeLa cells in order to determine if an increase in calcium levels alone would be sufficient to cause hTERT to exit the nucleus. Immunofluorescene was used to visualize fluorescent intensities of hTERT in the nucleus after administration of the drug in conjunction with visualization of Ran as an indicator of functional nuclear transport. We predicted thapsigargin would disrupt nuclear transport and cause hTERT to exit the nucleus. Image J software was used to compare nuclear fluorescence intensities between treated and control cells. Our results indicated that administration of thapsigargin caused a significant decrease in nuclear levels of hTERT in conjunction with decreased nuclear levels of Ran. Our findings could provide a potential method to induce cellular senescence in cancer cells by inducing mislocalization of hTERT and Ran.
Resistance Genes of Oryza sativa for Protection Against Xanthomonas oryzae pv. oryzae, the Causative Agent of Bacterial Leaf Blight
Authors: Horgan Katelyn Joy , Henderson Jeffrey Odell 
Published: September 2020

Rice (Oryza sativa) is a major staple crop around the world, particularly in developing regions such as Africa and Asia. Attack of the rice crop by pathogens has the capacity to greatly diminish crop yield with major agricultural, economical and human consequences. Xanthomonas orzyza pv. oryzae (Xoo), the causative agent of bacterial leaf blight, has the ability to cause substantial crop loss, up to 80% worldwide. Genetic sources of resistance have long been considered the most sustainable method of disease control, both from an environmental and agricultural perspective. This review considers the discovery, evolution, characterization and utilization of resistance genes (R genes) in rice against Xoo. R genes for Xoo are plentiful and exist at multiple loci throughout the rice genome due to multiple gene duplication and transposition events. The presence of multiple gene loci makes gene pyramiding and resistance stacking accessible and fruitful applications in breeding for resistance. Biotechnological approaches to take advantage of R gene function have also begun to take root. However, a more global and concerted effort to study the multiple varieties and climates in which rice is grown is required in order to truly attain food security and find sustainable resistance.
An Ethical Assessment on the Management of Sika Deer in Scotland; With Particular Reference to Hybridisation with Native Red Deer
Authors: Malcolm Sarah 
Published: September 2020

Globalisation and invasive alien species (IAS) are creating current and damaging effects worldwide. Wildlife management is necessary to preserve the biodiversity of our global flora and fauna, whilst balancing the needs of people with those of wildlife. It is imperative to work to achieve the optimal management strategy on various levels from financial, to ethical and practical. The genetic integrity of Scotland’s native red deer is threatened, following the introduction of sika deer and subsequent hybridisation. This review summarises the problems and potential management strategies associated, as a case study for IAS policy. ?
Treating a Dysregulated JAK/STAT Pathway in Cancer Cells
Authors: Schieler Jarod M. , Henderson Jeffrey O. 
Published: September 2020

The JAK/STAT pathway is induced by the binding of a cytokine to its cognate receptor. The receptor’s engagement with the cytokine recruits a JAK protein, which activates itself via auto/trans-phosphorylation. In turn, the activated JAKs recruit and phosphorylate STAT proteins. The phosphorylated STAT proteins form a dimer, translocate to the cell nucleus and acts as a transcription factor to induce gene expression. In this way, the JAK/STAT pathway can mediate a cell’s response to extracellular signals. The proteins ultimately induced by the JAK/STAT pathway contribute to processes such as inflammatory response, differentiation, proliferation, and apoptosis. When the JAK/STAT pathway becomes dysregulated, proto-oncogenes and/or tumor-suppressor genes are often inappropriately expressed, commonly resulting in oncogenesis. This review discusses how SOCS, PIAS, and PTPS proteins modulate the JAK/STAT pathway ensuring that it remains cyclic and transient. The use of jakibins, STAT inhibitors, decoy oligonucleotides, RNA interference and genome editing to synthetically regulate a dysregulated JAK/STAT pathway in cancer cells are also considered.
Sex and longevity: Why women live longer than men.
Authors: Peck Milagros S. , Porter Amber T , Hayes Breanna D , Otieno Dammah , Hargrove Angelina J , Mayhand Cynethia C , Johnson Anisa I , Brown Lynda M 
Published: September 2020

Sex differences in lifespan exist in most countries in the world, with women outliving men. This difference has existed for as long as records have been kept. This gap is not a uniquely human phenomenon; it exists in many animals as well. This is an important health issue that is not fully understood. Aging is a complex process. In this review we will examine the scientific basis for sex differences by focusing on four hypotheses that begin with examining why women are different from men. Men and women differ in our DNA. Women have two X chromosomes and men have an X and Y sex chromosome. Women have a second copy of the genes on the X chromosome which could be protective. Other hypotheses focus on the physiological difference between the sexes that result from the ratio of our sex hormones. Estrogen physiology changes women’s body shape, affects the major organs like the heart and as a result impacts longevity. Sex differences in longevity are important because this becomes a lens for us to examine nutrition, health and wellness.
A Test of Soccer Cleats Compared to Football Cleats during Football Speed and Agility Drills: Do Soccer Cleats Make You Faster or More Agile?
Authors: Mardis Benjamin R , Gassmann Caanan G , Senchina David S 
Published: September 2020

Background: Football players have many options in cleat styles and designs today. Skill position players especially may opt for soccer cleats over football cleats in the belief that the soccer cleats will help them run faster. Purpose: The purpose of this study was to compare soccer cleats to football cleats during common American football field drills. Methods: Sixteen young adult males performed a circuit of four American football speed and agility drills (forty yd-dash, ladder drill, 5-10-5-drill, and six-route route tree) in both soccer and football cleats. Performance measures (such as time or steps) were recorded for each drill. Subjects were asked to score the shoes in terms of comfort, heaviness, stability, and traction at various times. Results: Two significant differences were found as a result of this study. Out route times (seconds) were significantly different between football cleats and soccer cleats. The other significant difference occurred in the perceived heaviness of each cleat. Conclusion: This study found minimal difference between football and soccer cleats in performance and perception. Participants in this study showed split preferences as to which cleat was better for performance. Of four studied perceptual outcomes, only the heaviness perception was significantly different. This was further backed by performance data that had only one significant difference among seventeen performance-associated measurements.
The Search for Meaning and the Conundrum of Authority in The Castle
Authors: Lee Kenneth K. , Ross David 
Published: September 2020

Franz Kafka’s deliberation on the nature of authority in The Castle leads to the conclusion that though authority cannot be escaped, authority fosters communalism and facilitates interpersonal communication. Kafka’s titular Castle is an impenetrable, oftentimes nonsensical authority, but its inefficient bureaucracy does not lessen its power and instead strengthens it. Under its influence, K. undertakes a religious enterprise towards accepting the impenetrability of authority.
The Effects of Creatine on Blood Pressure Before, and After High Intensity Training
Authors: Schmitz Jacob , Jakes Tyler 
Published: September 2020

It is known that systolic blood pressure (SBP) drops five to seven mmHg for 22 hours immediately after a workout in individuals the have moderate hypertension, and that in individuals with optimal blood pressure (BP), one can expect to see a drop of four to five mmHg for over the following 22 hours. Creatine (CRE), one of the most recognized supplemental aids to enhance performance of high-intensity exercise, has convincingly substantiated its ergogenic potential (Naderi et al. 2016). However, little has been researched on the connection between creatine and blood pressure. The purpose of this study was to examine the effects of CRE on BP after a bout of high intensity strength training on Division III football players at Gustavus Adolphus College. This study is a one sample research design. Each athlete had their blood pressure measured four total times. One resting BP was taken before the consumption of CRE and the other was taken 18-22 hours after the consumption of creatine. The same was done when each subject participated in the control group as well. The subjects were given the creatine or placebo (control) at random for their first trial and then given the opposite for the second trial one week later. The independent variable was consumption of CRE. The dependent variables were SBP and diastolic blood pressure (DBP). The difference in SBP and DBP between the trials were calculated and analyzed using a paired sample t-test. Results showed that CRE trial BPs were slightly higher than in control trials although the difference was not significant (p&lt;0.05). The results of the study gave a better understanding of the effects of CRE on BP after a high intensity strength training session.
An Economic Exploration of Mining Industry of Northern Minnesota
Authors: Dambii Undralsaikhan , Mahjabeen Rubana 
Published: September 2020

Iron	ore	minining	industry	plays	a	big	role	in	northern Minnesota.	It	contributes	around	30	percent	of	the	regional	GDP.	In	recent	time	many	of	these	regional	mining	companies	are	laying	off	their	employees.	China	is	one	of	the	largest	economies	of	the	world.	As	such	it	has	great	impact	on	world’s	economy.	This	exploratory	study	investigates	if	there	is	some	connection between	Chinese	economic	slowdown	and	regional	mining	layoffs. For	this	purpose	this	paper	uses	relevant	news	articles,	academic papers,	expert	interviews	and	data	from	various	secondary	sources.	According	to	the	findings	of	this	study	multiple	factors	including	slowdown	of	Chinese	economy,	steel	dumping	by	China,	rising	world	production	of	iron	ore,	low	U.S.	domestic	demand	of	iron	ore,	low	iron	ore	price,	and,	natural	resource	boombust cycle	can	be	utilized in	explaining	these	regional mining layoffs.
Environment monitoring system in industrial area and Safety of workers
Authors: Al Fori Saif Sulaiman Hamood , Hussain Shaik Asif 
Published: September 2020

Environment monitoring system in industrial area and Safety of workers is system to monitor the pollution inside the factories and provide safety place for the workers and uses Wi-Fi to transfer the data to the control room. The main objective of the project is to monitor the pollution which comes from factories to protect the environment and workers inside factories are used to Measure the CO Content and getting a message through GSM the Value is transferred when it is more than the threshold. It also uses monitor the temperature and display on LCD, when the value more than the standard value by getting SMS on the GSM and Buzzer on. It also measures the PH level of the water and display the values on the LCD. These values of humidity is displayed on LCD. One of the specific function of this system is it by Count the number of workers who are entry or leaving from the factory. A wireless System is used to Transfer these data (temperature and IR) to remote monitoring station.
Use of Ceramic Powder in Concrete - Strength & Durability Properties
Authors: Poloju Kiran Kumar , Tahir Abdullah 
Published: September 2020

Ceramic wall tiles are used as building material in the field of construction. Manufacturing of ceramic tiles require different raw material like clay, potash, dolomite, feldspar, talc and different chemicals like sodium silicate, sodium tripoly, phosphate (STPP) in ceramic production. In the ceramic industry, about 15%-30% production goes as waste. These wastes poses a serious threat to the environment by polluting the habitant and agricultural lands. Therefore using of ceramic waste powder in concrete would benefit in many ways in saving energy & protecting the environment. The cost of deposition of ceramic waste in landfills will be saved. Raw materials and natural resources will be replaced. Which indirectly helps for reducing the greenhouse gas (co2).There is a large amount of carbon dioxide released in the cement production. In this research study the (OPC) cement has been replaced by ceramic waste powder accordingly in the range of 0%, 10%, 20%, 30% 40%, & 50% by weight for M-25 grade concrete. The wastes employed came from ceramic industry which is in Rusayl (Muscat, Oman) industrial area. Based on experimental investigations concerning the compressive strength of concrete, the following observations are made: (a) The Compressive Strength of M25 grade concrete increases when the replacement of cement with ceramic waste up to 30% by weight of cement and further replacement of cement with ceramic powder decreases the compressive strength. (b) Concrete on 30% replacement of cement with ceramic waste, compressive strength obtained is 26.77 N/mm2and vice-versa the cost of the concrete is reduced up to 13.27% in M25 grade and hence it becomes more economical without compromising concrete strength than the standard concrete. It becomes technically and economically feasible and viable. It is the possible alternative solution of safe disposal of ceramic waste. Reuse of this kind of waste has advantages economic and environmental, reduction in the number of natural spaces employed as refuse dumps. Indirectly, all the above contributes to a better quality of life for citizens and to introduce the concept of sustainability in the construction sector.
Multiple Objective Decision Based Modern Digital Home With Hybrid Renewable Energy Sources
Authors: Nasser Khamis Al-Maskari Ahmed , Mohammad Al Al-Siyabi Saeed Sultan , Habin Al Habsi Hamed Obaid , P GopiKrishna 
Published: September 2020

Day to day the technology is advancing and it’s becoming a part of our life. In this situation this project will provides an innovative and a complete solution for home automation based on multiple objectives. These objectives involve the switching ON/ OFF of home appliances automatically using different sensors, GSM modules, Smart phones with Bluetooth control, Smart phones with voice control, House security through GSM, Camera modules to send SMS, MMS when an unknown person entered into our locked house, Water tank level monitoring, Gas level, leakage monitoring systems, RFID (Radio Frequency Identification) locks and Number locks in the place of manual locks. These all objectives are innovatively incorporated into our proposed prototype home model using Arduino and Raspberry Pi microcontrollers, GSM, Blue tooth, camera modules, RFID, Number lock and different sensors. Among all these objectives gas level monitoring, water tank level monitoring are our own proposed methods implemented successfully. We proposed and developed a multiple objective based a complete solution for home automation which will make or initiate the Omani people towards Modern home to lead their life more comfortably, securely and providing their contribution in saving the energy for the Oman and as well as to reduce Global warming.
BENTUK POLITIK UANG PADA PILKADA PROVINSI BENGKULU TAHUN 2015
Authors: Suprianto Dede , Purwaningsih Titin , Rusnaedy Zaldi 
Published: September 2020

Artikel ini menjelaskan tentang politik uang yang terjadi pada Pilkada di Provinsi Bengkulu tahun 2015. Metode yang digunakan dalam penelitian ini adalah kualitatif, dengan menggunakan teknik pengumpulan data yaitu wawancara dan dokumentasi. Sedangkan yang menjadi sasaran penelitian ini adalah Bawaslu, KPUD dan Tim Sukses. Hasil penelitian ini menunjukkan bahwa bentuk politik uang terdiri dari vote buying sebanyak 33 kasus, vote trading sebanyak 2 kasus dan club goods sebanyak 1 kasus. Semua laporan tersebut tidak ditindaklanjuti karena tidak memenuhi syarat formal dan materil serta kedaluwarsa, kecuai kasus PPK Singaran Pati yang digugat pasangan Sultan-Mujiono ke Mahkamah Konstitsi. Meskipun MK akhirnya menolak gugatan tersebut berdasarkan pertimbangan ambang batas suara antara pemohon dan peraih suara terbanyak dengan selisih diantara keduanya sebesar 14%.
Implementasi Pelayanan Publik Pada Program SIDUKUN 3 In 1 Dalam Pengurusan Administrasi Kependudukan Di DKI Jakarta
Authors: Idrus Iqbal Aidar , Ferdian Komang Jaka 
Published: September 2020

Penelitian ini menjawab Implementasi program SIDUKUN 3 In 1 dalam pelaksanaan pelayanan administrasi kependudukan. Program tersebut dikembangkan untuk mengimplementasikan Undang-Undang No. 24 Tahun 2013 tentang Administrasi Kependudukan (Adminduk). Metode Penelitian yang digunakan dalam penelitian ini yaitu penelitian deskriptif kualitatif, yang dilakukan di Dinas Kependudukan dan Catatan Sipil DKI Jakarta yang saling terintegrasi dengan instansi rumah sakit dan BPJS Kesehatan terkait dengan kualitas pelayanan administrasi kependudukan. Hasil penelitian ini menunjukan bahwa pemerintah DKI Jakarta cukup berhasil melaksanakan pelayanan administrasi kependudukan, akan tetapi masih kurang dalam mesosialisasikan program tersebut. Sehingga masih banyak masyarakat yang belum mengetahui program “SIDUKUN 3 in 1” dalam memberikan layanan bagi anak yang dilahirkan di rumah sakit, langsung mendapatkan Surat Keterangan Kelahiran dari rumah sakit, Nomor Induk Kependudukan (NIK) bayi, Kartu keluarga yang sudah update, akta kelahiran, kartu identitas anak dan BPJS Kesehatan untuk bayi. Dengan pengurusan pelayanan yang cepat dan tidak dipungut biaya, pada tahun 2019 sudah 79 rumah sakit, 44 puskesmas dan 5700 akte kelahiran yang sudah di cetak oleh Dinas Dukcapil.
Perlindungan Pemerintah Daerah Terhadap Kelompok Minoritas “Towani Tolotang” di Sulawesi Selatan
Authors: Lawelai Herman 
Published: September 2020

This article describes the efforts of the regional government to protect the Towani Tolotang people as a minority group in fighting for their identity, the argumentation of justice and group rights in the midst of a pluralistic culture. This article is analyzed with; historical agreements, equal rights, and cultural diversity. Using qualitative research methods, this study found that until now the minority group "Towani Tolotang" still exists in cultural practices as well as in social interactions with the wider community. Relations between communities are supported by local government policy by providing forums that embrace interfaith community leaders, security forces and government elements in fostering community.
Artikel ini menggambarkan upaya pemerintah daerah untuk melindungi masyarakat Towani Tolotang sebagai kelompok minoritas dalam memperjuangkan identitas mereka, argumentasi keadilan dan hak-hak kelompok di tengah-tengah budaya pluralistik. Artikel ini dianalisis dengan; perjanjian sejarah, persamaan hak, dan keanekaragaman budaya. Menggunakan metode penelitian kualitatif, penelitian ini menemukan bahwa sampai sekarang kelompok minoritas "Towani Tolotang" masih ada dalam praktik budaya serta dalam interaksi sosial dengan masyarakat luas. Hubungan antar masyarakat didukung oleh kebijakan pemerintah daerah dengan menyediakan forum yang merangkul tokoh masyarakat lintas agama, pasukan keamanan dan elemen pemerintah dalam membina masyarakat.
Media Sosial dan Pergulatan Masyarakat Muslim Indonesia di Inggris: Merayakan ‘Ingatan’ tentang Tanah Air dalam Konteks ‘Lokal’
Authors: Basya M. Hilali 
Published: September 2020

Semakin meningkatnya teknologi komunikasi membuat cara berinteraksi masyarakat dan otoritas keilmuan mengalami pergeseran. Saat ini media sosial (medsos) seperti Facebook (FB) dan Whatsapp (WA) menjadi media yang paling sering digunakan dalam berkomunikasi, baik dalam bentuk percakapan singkat maupun diskusi yang mendalam. Meskipun percakapan secara langsung (face to
face) antar individu dan diskusi dalam forum masih tetap terjadi, namun aktifitas semacam ini mengalami peningkatan dalam dunia maya terutama melalui FB dan WA. Konsekuensinya, sebuah diskusi yang sebelum dominasi medsos hanya melibatkan narasumber atau komentator secara terbatas dan sesuai dengan keahliannya, saat ini bisa menempatkan siapapun berada dalam posisi tersebut. Semua orang, termasuk yang awam sekalipun, bisa menjadi narasumber yang sepertinya sangat memahami sebuah topik. Artikel ini mengkaji tentang bagaimana masyarakat Muslim Indonesia di Inggris menggunakan medsos. Sebagian besar dari mereka adalah dosen, aktifis, ulama muda, birokrat, dan lain-lain yang sedang menempuh pendidikan tingkat S2 atau S3. Hidup dalam nilai-nilai, norma, dan kebudayaan yang berkembang dalam masyarakat Inggris yang tentu saja memiliki perbedaan dengan di Indonesia menjadi konteks sosial yang menarik untuk dikaji. Fokus yang ingin dijelaskan dalam artikel ini adalah bagaimana pengaruh konteks sosial tersebut terhadap cara masyarakat Muslim Indonesia di Inggris menggunakan media sosial.