bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prescribed psychiatric interventions for children presented to a university psychiatric clinic in Egypt: a descriptive cross-sectional study
Authors: Ghaly Ahmed Sami , Tobar Salwa Mohamed Salah , El-Hadidy Mohamed Adel , Elwasify Mahmoud 
Published: November 2020

Abstract
Background
The number of children diagnosed with psychiatric disorders has significantly increased over the past two decades. This study examined the pattern of psychiatric interventions prescribed for a sample of children with mental health problems in Egypt. A descriptive cross-sectional study was conducted to examine the pattern of psychotropic drug prescribing and intervention (medication, doses, duration, side effects, and improvement) in children aged 2-12 years old in primary and secondary health settings, presented to Mansoura University Hospitals in Egypt over 1 year. The identified patterns were compared with the Maudsley guidelines to detect any significant deviations.

Results
Among the 272 cases presented to the clinic, attention-deficit hyperactivity disorder (ADHD) and disruptive behavior disorders were the most prevalent diagnoses (85.3%) followed by intellectual disability (7.8%) and autism spectrum disorder (ASD; 5.1%). Antipsychotic drugs and ADHD medications (atomoxetine and methylphenidate) represented the most commonly prescribed medications (56.6% and 44.5% respectively), whereas behavioral therapy was among the least chosen (8.5%) treatment options. About 1/3 of the sample received multiple psychotropic medications. The prescribed intervention strategies did not match the Maudsley’s guidelines in 76% of the cases with the absence of psychotherapeutic interventions being the most frequently observed factor (95.7%). Although still inadequate, psychiatrists’ intervention strategies were more likely to follow the Maudsley’s guidelines (38.3%), whereas pediatricians and neurologists were almost oblivious to them.

Conclusions
Current pattern of psychiatric interventions prescribed for a sample of children with mental health problems in Egypt are not in accordance with standard guidelines, such as “Maudsley’s,” rendering it imperative to provide relevant educational programs for health care providers.
No evidence for Ago2 translocation from the host erythrocyte into the Plasmodium parasite
Authors: Hentzschel Franziska , Obrova Klara , Marti Matthias 
Published: November 2020

Background:Plasmodiumparasites rely on various host factors to grow and replicate within red blood cells (RBC). While many host proteins are known that mediate parasite adhesion and invasion, few examples of host enzymes co-opted by the parasite during intracellular development have been described. Recent studies suggested that the host protein Argonaute 2 (Ago2), which is involved in RNA interference, can translocate into the parasite and affect its development. Here, we investigated this hypothesis.Methods: We used several different monoclonal antibodies to test for Ago2 localisation in the human malaria parasite,P. falciparumand rodentP. bergheiparasites. In addition, we biochemically fractionated infected red blood cells to localize Ago2. We also quantified parasite growth and sexual commitment in the presence of the Ago2 inhibitor BCI-137.Results: Ago2 localization by fluorescence microscopy produced inconclusive results across the three different antibodies, suggesting cross-reactivity with parasite targets. Biochemical separation of parasite and RBC cytoplasm detected Ago2 only in the RBC cytoplasm and not in the parasite. Inhibition of Ago2 using BCl-137 did not result in altered parasite development.Conclusion: Ago2 localization in infected RBCs by microscopy is confounded by non-specific binding of antibodies. Complementary results using biochemical fractionation and Ago2 detection by western blot did not detect the protein in the parasite cytosol, and growth assays using a specific inhibitor demonstrated that its catalytical activity is not required for parasite development. We therefore conclude that previous data localising Ago2 to parasite ring stages are due to antibody cross reactivity, and that Ago2 is not required for intracellularPlasmodiumdevelopment.
Tracking Excess Deaths (TRACKED) – an interactive online tool to monitor excess deaths associated with the COVID-19 pandemic in the United Kingdom
Authors: Poon Michael T. C. , Brennan Paul M. , Jin Kai , Figueroa Jonine D. , Sudlow Cathie L. M. 
Published: November 2020

Background: We aimed to describe trends of excess mortality in the United Kingdom (UK) stratified by nation and cause of death, and to develop an online tool for reporting the most up to date data on excess mortality Methods: Population statistics agencies in the UK including the Office for National Statistics (ONS), National Records of Scotland (NRS), and Northern Ireland Statistics and Research Agency (NISRA) publish weekly mortality data. We used mortality data up to 22nd May in the ONS and the NISRA and 24th May in the NRS. The main outcome measures were crude mortality for non-COVID deaths (where there is no mention of COVID-19 on the death certificate) calculated, and excess mortality defined as difference between observed mortality and expected average of mortality from previous 5 years. Results: There were 56,961 excess deaths, of which 8,986 were non-COVID excess deaths. England had the highest number of excess deaths per 100,000 population (85) and Northern Ireland the lowest (34). Non-COVID mortality increased from 23rd March and returned to the 5-year average on 10th May. In Scotland, where underlying cause mortality data besides COVID-related deaths was available, the percentage excess over the 8-week period when COVID-related mortality peaked was: dementia 49%, other causes 21%, circulatory diseases 10%, and cancer 5%. We developed an online tool (TRACKing Excess Deaths - TRACKED) to allow dynamic exploration and visualisation of the latest mortality trends. Conclusions: Continuous monitoring of excess mortality trends and further integration of age- and gender-stratified and underlying cause of death data beyond COVID-19 will allow dynamic assessment of the impacts of indirect and direct mortality of the COVID-19 pandemic.
Design and implementation of a high-performance panoramic annular lens
Authors: Zhou Qing , Tian Yuhan , Wang Junhua , Xu Min 
Published: November 2020

In this work, a high-performance panoramic annular lens system designed with a point-by-point method and variable parameter optimization strategies is proposed. Due to the optimization and design, the system maintains a balance among characteristic parameters and can achieve a

360

∘

×
(

40

∘

−

95

∘

)

field of view with a 4.34 mm focal length, an

f

-number of 4.5, and an

F

−

θ

distortion of less than 0.5%. Experimental results verify the parameters and demonstrate that the distortion is less than 0.8%, except in some areas with mechanical damage on the ogive surface.
Accuracy of intraocular lens calculation formulas in cataract patients with steep corneal curvature
Authors: Zhang Chenguang , Dai Guangzheng , Pazo Emmanuel Eric , Xu Ling , Wu Xianwei , Zhang Hongda , Lin Tiezhu , He Wei 
Published: November 2020

Objective
To compare the accuracy of five kinds of intraocular lens calculation formulas (SRK/T, Haigis, Hoffer Q, Holladay and Barrett Universal Ⅱ) in cataract patients with steep curvature cornea ≥ 46.0 diopters.

Methods
This is a retrospective study of cataract phacoemulsification combined with intraocular lens implantation in patients with steep curvature cornea (corneal curvature ≥ 46D). The refractive prediction errors of IOL power calculation formulas (SRK/T, Haigis, Holladay, Hoffer Q, and Barrett Universal II) using User Group for Laser Interference Biometry (ULIB) constants were evaluated and compared. Objective refraction results were assessed at one month postoperatively. According to axial length (AL), all patients were divided into three groups: short AL group (<22mm), normal AL group (>22 to ≤24.5mm) and long AL group (>24.5mm). Calculate the refractive error and absolute refractive error (AE) between the actual postoperative refractive power and the predicted postoperative refractive power. The covariance analysis was used for the comparison of five formulas in each group. The correlation between the absolute refractive error and AL from every formula were analyzed by Pearson correlation test, respectively.

Result
Total 112 eyes of 83 cataract patients with steep curvature cornea were collected. The anterior chamber depth (ACD) was a covariate in the short AL group in the covariance analysis of absolute refractive error (P<0.001). The SRK/T and Holladay formula had the lowest mean absolute error (MAE) (0.47D), there were statistically significant differences in MAE between the five formulas for short AL group (P = 0.024). The anterior chamber depth had no significant correlation in the five calculation formulas in the normal AL group and long AL group (P = 0.521, P = 0.609 respectively). In the normal AL group, there was no significant difference in MAE between the five calculation formulas (P = 0.609). In the long AL group, Barrett Universal II formula had the lowest MAE (0.35), and there were statistically significant differences in MAE between the five formulas (P = 0.012). Over the entire AL range, the Barrett Universal II formula had the lowest MAE and the highest percentage of eyes within ± 0.50 D, ± 1.00 D, and ± 1.50 D (69.6%, 93.8%, and 98.2% respectively).

Conclusion
Compared to SRK/T, Haigis, Hoffer Q, and Holladay, Barrett Universal Ⅱ formula is more accurate in predicting the IOL power in the cataract patients with steep curvature cornea ≥ 46.0 diopters.
Performance of serum apolipoprotein-A1 as a sentinel of Covid-19
Authors: Poynard Thierry , Deckmyn Olivier , Rudler Marika , Peta Valentina , Ngo Yen , Vautier Mathieu , Akhavan Sepideh , Calvez Vincent , Franc Clemence , Castille Jean Marie , Drane Fabienne , Sakka Mehdi , Bonnefont-Rousselot Dominique , Lacorte Jean Marc , Saadoun David , Allenbach Yves , Benveniste Olivier , Gandjbakhch Frederique , Mayaux Julien , Lucidarme Olivier , Fautrel Bruno , Ratziu Vlad , Housset Chantal , Thabut Dominique , Cacoub Patrice 
Published: November 2020

BackgroundSince 1920, a decrease in serum cholesterol has been identified as a marker of severe pneumonia. We have assessed the performance of serum apolipoprotein-A1, the main transporter of HDL-cholesterol, to identify the early spread of coronavirus disease 2019 (Covid-19) in the general population and its diagnostic performance for the Covid-19.MethodsWe compared the daily mean serum apolipoprotein-A1 during the first 34 weeks of 2020 in a population that is routinely followed for a risk of liver fibrosis risk in the USA (212,297 serum) and in France (20,652 serum) in relation to a local increase in confirmed cases, and in comparison to the same period in 2019 (266,976 and 28,452 serum, respectively). We prospectively assessed the sensitivity of this marker in an observational study of 136 consecutive hospitalized cases and retrospectively evaluated its specificity in 7,481 controls representing the general population.ResultsThe mean serum apolipoprotein-A1 levels in the survey populations began decreasing in January 2020, compared to the same period in 2019. This decrease was highly correlated with the daily increase in confirmed Covid-19 cases in the following 34 weeks, both in France and USA, including the June and mid-July recovery periods in France. Apolipoprotein-A1 at the 1.25 g/L cutoff had a sensitivity of 90.6% (95%CI84.2–95.1) and a specificity of 96.1% (95.7–96.6%) for the diagnosis of Covid-19. The area under the characteristics curve was 0.978 (0.957–0.988), and outperformed haptoglobin and liver function tests. The adjusted risk ratio of apolipoprotein-A1 for survival without transfer to intensive care unit was 5.61 (95%CI 1.02–31.0; P = 0.04).ConclusionApolipoprotein-A1 could be a sentinel of the pandemic in existing routine surveillance of the general population. NCT01927133, CER-2020-14.
Nursery teachers in preschool institutions facing burnout: Are personality traits attributing to its development?
Authors: Tasic Radica , Rajovic Nina , Pavlovic Vedrana , Djikanovic Bosiljka , Masic Srdjan , Velickovic Igor , Mostic Danka , Cumic Jelena , Milcanovic Petar , Janicijevic Valerija , Stanisavljevic Dejana , Milic Natasa 
Published: November 2020

IntroductionThe aim of the study was to assess the prevalence of burnout syndrome among nursery teachers in Belgrade's preschool institutions, and to assess the role of personality traits in its development.Materials and methodsA cross-sectional study was conducted in all Belgrade’s preschool institutions. A stratified cluster sampling method was used to obtain a representative sample. Burnout was measured using the Maslach Burnout Inventory- General Survey (MBI-GS). The MBI-GS adaptation was based on an internationally accepted methodology for translation and cultural adaptation. Psychometric properties of the Serbian version of the MBI-GS were analyzed through the examination of factorial structure and internal consistency. A shortened version of Big Five Plus Two questionnaire was used to measure Personality traits.ResultsThree hundred two health care professionals were enrolled. The mean age was 38±9.2 years and all were female. Confirmatory factor analysis validated the three-factor structure of the questionnaire (exhaustion, cynicism and professional efficacy). Overall, 251 (83.1%) respondents were found to have moderate burnout. In multiple regression analysis, positive valence and conscientiousness were significantly associated with professional efficacy. Aggressiveness, neuroticism, openness, and age, were significantly associated with exhaustion. Aggressiveness, neuroticism and additional jobs showed association with cynicism.ConclusionPresent study provided the evidence for the appropriate metric properties of the Serbian version of MBI-GS. Most nurses demonstrated moderate burnout level. Personality traits are characteristics that affect presence of burnout syndrome in healthcare professionals working in preschool institutions.
Assessing the effect of pregnancy intention at conception on the continuum of care in maternal healthcare services use in Bangladesh: Evidence from a nationally representative cross-sectional survey
Authors: Khan Md Nuruzzaman , Harris Melissa L. , Loxton Deborah 
Published: November 2020

Background
The Continuum of Care (CoC; defined as accessing the recommended healthcare services during pregnancy and the early postpartum period) is low in lower-middle-income countries (LMICs). This may be a major contributor to the high rates of pregnancy-related complications and deaths in LMICs, particularly among women who had an unintended pregnancy. With a lack of research on the subject in Bangladesh, we aimed to examine the effect of unintended pregnancy on CoC.

Methods
Data from 4,493 mother-newborn dyads who participated in the cross-sectional 2014 Bangladesh Demographic and Health Survey were analysed. Women’s level of CoC was generated from responses to questions on the use and non-use of three recommended services during the course of pregnancy: four or more antenatal care (ANC) visits, skilled birth attendance (SBA) during delivery, and at least one postnatal care (PNC) visit within 24 hours of giving birth. Global recommendations of service use were used to classify CoC as high (used each of the recommended services), moderate (used at least two of the three recommended services), and low/none (no PNC, no SBA, and ≤3 ANC visits). Women’s pregnancy intention at the time of conception of their last pregnancy (ending with a live birth) was the major exposure variable, classified as wanted, mistimed, and unwanted. Unadjusted and adjusted (with individual-, household-, and community-level factors) multilevel multinomial logistic regression models were used to assess the association between unintended pregnancy and level of CoC.

Results
In Bangladesh, the highest level of CoC occurred in only 12% of pregnancies that ended with live births. This figure was reduced to 5.6% if the pregnancy was unwanted at conception. The antenatal period saw the greatest drop in CoC, with 65.13% of women receiving at least one ANC visit and 26.32% having four or more ANC visits. Following the adjustment of confounders, an unwanted pregnancy was found to be associated with 39% and 62% reduced odds of women receiving moderate and high levels of CoC, respectively, than those with a wanted pregnancy. Having a mistimed pregnancy was found to be associated with a 31% reduction in odds of women achieving a high CoC than women with a wanted pregnancy.

Conclusion
Almost nine in ten women did not achieve CoC in their last pregnancy, which was even higher when the pregnancy was unintended. Given that the ANC period has been identified as a critical time for intervention for these women, it is necessary for policies to scale up current maternal healthcare services that provide in-home maternal healthcare services and to monitor the continuity of ANC, with a particular focus on women who have an unintended pregnancy. Integration of maternal healthcare services with family planning services is also required to ensure CoC.
Pixel Grouping of Digital Images for Reversible Data Hiding
Authors: Hasib Sultan Abdul , Nyeem Hussain Md Abu 
Published: November 2020

Pixel Grouping (PG) of digital images has been a key consideration in recent development of the Reversible Data Hiding (RDH) schemes. While a PG kernel with neighborhood pixels helps compute image groups for better embedding rate-distortion performance, only horizontal neighborhood pixel group of size 1×3 has so far been considered. In this paper, we formulate PG kernels of sizes 3×1, 2×3 and 3×2 and investigate their effect on the rate-distortion performance of a prominent PG-based RDH scheme. Specially, a kernel of size 3×2 (or 2×3) that creates a pair of pixel-trios having triangular shape and offers a greater possible correlation among the pixels. This kernel thus can be better utilized for improving a PG-based RDH scheme. Considering this, we develop and present an improved PG-based RDH scheme and the computational models of its key processes. Experimental results demonstrated that our proposed RDH scheme offers reasonably better embedding rate-distortion performance than the original scheme.
O sentido do ato de educar em Edgar Morin
Authors: Martinazzo Celso José 
Published: November 2020

Temos como propósito, neste texto, contribuir com o debate acerca da razão de ser da escola, bem como do sentido e das finalidades da educação. A reflexão tem como fonte de inspiração a obra do pensador francês Edgar Morin com o objetivo de compreender quais deveriam ser as grandes finalidades do processo educacional. O estudo é de cunho bibliográfico tendo como horizonte os princípios da complexidade. A pesquisa permite concluir que, em seus primeiros escritos, Morin aponta para a necessidade de instituir uma política de civilização que contemple o contexto planetário da humanidade. Com o decorrer do tempo e, sobretudo, nos escritos mais recentes, Morin ressignifica o pensamento de Montaigne e de Rousseau: com inspiração em Montaigne indica que cabe à escola formar o aluno com uma cabeça benfeita e com base em Rousseau retoma a ideia de que é função da escola ensinar a viver.
Palavras-chave: Pensamento complexo. Reforma do pensamento. Sentido da educação.
Neoprene Knee Sleeves of Varying Tightness Augment Barbell Squat One Repetition Maximum Performance Without Improving Other Indices of Muscular Strength, Power, or Endurance
Authors: Machek Steven B. , Cardaci Thomas D. , Wilburn Dylan T. , Cholewinski Mitchell C. , Latt Scarlett Lin , Harris Dillon R. , Willoughby Darryn S. 
Published: November 2020

Abstract
Machek, SB, Cardaci, TD, Wilburn, DT, Cholewinski, MC, Latt, SL, Harris, DR, and Willoughby, DS. Neoprene knee sleeves of varying tightness augment barbell squat one repetition maximum performance without improving other indices of muscular strength, power, or endurance. J Strength Cond Res 35(2S): S6–S15, 2021—Neoprene knee sleeves are commonly used by powerlifters and recreational users but are heavily under-researched. Furthermore, no data exist on whether knee sleeves of varying compressive tightness impact muscular performance similar to commonly used knee wraps, which are both generally effective and more so when increasingly constrictive. Fifteen resistance trained, knee sleeve naive, recreational weight lifting men (22.1 ± 4.1 years; 177.5 ± 5.9 cm; 87.8 ± 7.8 kg) visited the laboratory on 3 separate occasions one week apart, assigned in a randomized, crossover, and counterbalanced fashion to either a minimally supportive control sleeve (CS) condition, a manufacturer-recommended sizing neoprene knee sleeve (“normal” sleeve; NS), or a one size smaller (than NS) neoprene knee sleeve (tighter sleeve [TS]). On each visit, subjects sequentially completed vertical jump (countermovement and squat jumps for both peak and mean power), one repetition maximum (1RM) barbell squat, and GymAware assessments (peak power, peak velocity, and dip) at 90% (reported) and 100% (tested) 1RM as well as one-leg extension (1RM, repetitions to failure, and total volume load at 75% 1RM) tests. All data were analyzed using one-way repeated measures analysis of variance at p < 0.05. Analysis revealed a significant condition effect on barbell squat 1RM (p = 0.003; η2 = 0.339), whereby both NS (p = 0.044; 166 ± 24 kg) and TS (p = 0.019; 166 ± 21 kg) outperformed CS (161 ± 22 kg), with no difference between neoprene sleeves. Conversely, no other tested parameters differed between knee sleeve conditions (p ≥ 0.05). The present results demonstrate that neoprene knee sleeves may function independent of tightness, relative to recommended sizing and ultimately unlike knee wraps. Furthermore, the singular benefits observed on barbell squat maximal strength potentially suggests an exercise-specific benefit yet to be fully elucidated.