bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autophagy Compensates for Lkb1 Loss to Maintain Adult Mice Homeostasis and Survival
Authors: Khayati Khoosheh , Bhatt Vrushank , Hu Zhixian Sherrie , Fahumy Sajid , Luo Xuefei , Guo Jessie Yanxiang 
Published: August 2020

AbstractLiver Kinase B1 (LKB1) is the major energy sensor for cells to respond to metabolic stress. Autophagy degrades and recycles proteins, macromolecules, and organelles for cells to survive starvation. To access the role and cross-talk between autophagy and Lkb1 in normal tissue homeostasis, we generated genetically engineered mouse models where we can conditionally deleteLkb1and autophagy essential gene,Atg7, respectively or simultaneously, throughout the adult mice. We found that Lkb1 was essential for the survival of adult mice, and autophagy activation could temporarily compensate for the acute loss of Lkb1 and extend mouse life span. We further found that acute deletion of Lkb1 in adult mice led to impaired intestinal barrier function, hypoglycemia, and abnormal serum metabolism, which was partly rescued by the Lkb1 loss-induced autophagy upregulation via inhibiting p53 induction. Taken together, we demonstrated that autophagy and Lkb1 work synergistically to maintain adult mouse homeostasis and survival.
The effect of online learning on communication between instructors and students during Covid-19 pandemic
Authors: Alawamleh Mohammad , Al-Twait Lana Mohannad , Al-Saht Gharam Raafat 
Published: August 2020

PurposeThis study aims to explore whether online learning has an effect on communication between instructors and students in a negative way, whether online learning affects students' productivity levels and to evaluate and suggest ways of improving effective online communication between instructors and students.Design/methodology/approachThis study used is a quantitative research study which was conducted through a semi-structured online survey through a random sample technique.FindingsResults revealed that the vast majority agree with the questions of the study. Students still prefer classroom classes over online classes due to many problems they face when taking online classes, such as lack of motivation, understanding of the material, decrease in communication levels between the students and their instructors and their feeling of isolation caused by online classes.Research limitations/implicationsThis research studied the impact from students' perspective only as the sample was selected only from students.Originality/valueThis research reached the students’ point of view in a broader way which will help understanding the issues and provide effective solutions. This research suggested that instructors must communicate with their students and vice versa in more informal channels (instant messages online chat groups, audio calls, private video calls …) in parallel with the formal channels (online platforms, email …). Finally, instructors should encourage students to participate and study more by providing different kind of incentives.
Service quality assessment model for academic libraries
Authors: Alam Md. Jahangir , Mezbah-ul-Islam Muhammad 
Published: August 2020

Purpose
The purpose of this paper is to develop a service quality assessment model for academic libraries using SERVQUAL and validate the model surveying teachers, students and researchers.

Design/methodology/approach
A model was developed, including 28 statements of five dimensions using the SERVQUAL instrument. It incorporated three segments, i.e. minimum service expectation, desired service expectation and actual service performance with a seven-point Likert scale. The minimum service expectation and desired service expectation appear at both ends of the tolerance zone, which represents the range of satisfactory service performance. A performance level upper tolerance zone could delight users, or service performance below the tolerance zone would cause dissatisfaction. A survey was conducted among 552 respondents from ten private university libraries of Bangladesh to validate the model.

Findings
Several statistical methods like Cronbach’s alpha (0.986), Bartlett’s test (0.001), rotation sums of squared loadings (74.26) in factor analysis, item loading (0.671‐0.839), commonalities (0.579‐0.859), Kaiser–Meyer–Olkin value (0.971), construct reliability (0.862‐0.910) and AVE value (0.510‐0.660) supported reliability and validity of the model. The actual service performance of all dimensions existed within the tolerance zone of the respective dimensions. Besides, the overall service performance (5.11) resided within the tolerance zone (4.73‐5.84), indicating the users were satisfied with the service provided by their libraries.

Originality/value
The model was developed in the current context of university libraries, which produced appropriate results. It will prompt further research on service quality assessment in academic libraries globally.
Thematic analysis of destination images for social media engagement marketing
Authors: Song Seobgyu , Park Seunghyun “Brian” , Park Kwangsoo 
Published: August 2020

PurposeThis study assessed the effect of photo themes to facilitate social media user engagement in Facebook brand pages and emphasized the important role of designing images for developing destination marketing strategies.Design/methodology/approachThis study analyzed 8,900 posts that were published by official tourism destination marketers for each destination (Hong Kong, Japan, South Korea). Text mining analysis, image thematic coding analysis and two-way ANOVA were applied to examine the significant differences across proposed determinants for the following engagements: the numbers of likes, comments and shares.FindingsThe results indicated that photographs on social media of three tourism destinations can be explored based on 11 categories of image themes. The themes' significant and distinct effects on three indicators of social media engagement were verified.Originality/valueThis research presented methodological insights by integrating thematic and statistical analyses with social media analytics. The findings of this study provided theoretical evidence of the importance of image themes in the context of social media engagement marketing. Based on the implications of this study, practitioners would enhance the effectiveness of social media marketing.
The three pillars of institutional theory and IFRS implementation in Nigeria
Authors: Osinubi Igbekele Sunday 
Published: August 2020

PurposeThis study explores the effects of the three pillars of institutional theory in shaping the activities of institutional entrepreneurs and other social actors during International Financial Reporting Standards (IFRS) implementation in Nigeria.Design/methodology/approachThis study uses a document analysis method to achieve the objectives of the study.FindingsThis study finds that IFRS implementation in Nigeria witnessed some progression from regulative to normative to cognitive pillar building. The regulation on IFRS implementation was initiated top-down rather than through lobbying from professional accounting bodies and the public. Changes in the regulatory framework brought some improvement to corporate financial reporting practices such as the timing of corporate filings of audited financial reports. However, the implementation process is laden with conflicts and power struggle among institutional actors. These conflicts and power struggles led the President of Nigeria to sack the Board of the Financial Reporting Council of Nigeria (FRC), the reconstitution of the Board and appointment of a Chairman for the Board of the FRC.Practical implicationsIFRS implementation process resulted in power redistribution among institutional actors, which led to resistance, tensions and conflicts among institutional actors. The conflicts arise from the need of actors to legitimate their activities and secure their positions. The three institutional pillars are key components of a change process and the actor's social position affects their capability to act as an institutional entrepreneur.Originality/valueThis finding should provide foundational knowledge that will inform practitioners, researchers and regulators in developing countries on how institutional actors shape the approach to corporate reporting regulations.
A model of perceptions of politics: antecedents and outcomes
Authors: Al Jisr Sakina Abbad , Beydoun Abdul Rahman , Mostapha Nehale 
Published: August 2020

PurposeThe purpose of this paper is to examine the influence of one personal variable (locus of control) and two relationship variables (leader-member exchange and co-worker cooperation) on perceptions of organizational politics in Lebanese small and medium-sized enterprises (SMEs).Design/methodology/approachSurvey data was collected from 300 Lebanese employees from different SMEs located between Tripoli and Beirut.FindingsResults of regression analysis indicated that all the three variables were significant predictors of perceptions of politics, and that perceptions of politics affected employee outcomes. More specifically, higher levels of politics are associated with higher turnover intention and lower job satisfaction.Practical implicationsResults of this study raise several implications for companies and employers. Perceptions of politics were found to have a negative impact on employee attitudinal and behavioral outcomes. Therefore, employers must examine the factors that affect employee perceptions of politics in the workplace. Since leader-member exchange and co-worker cooperation were found to predict politics, management's efforts should focalize on improving the relationships between employees and their supervisor as well as their relationships with each other. Management should develop strategies to create an atmosphere of cooperation and support in the organization.Originality/valueThere is paucity of studies on organizational politics in Arabic cultures. This study extends the organizational politics literature by investigating antecedents and outcomes of politics in Lebanon, a country that differs in its culture from US and European contexts.
The role of perceived high-performance HR practices and transformational leadership on employee engagement and citizenship behaviors
Authors: Hai Shenyang , Wu Kai , Park In-Jo , Li Yongxin , Chang Quan , Tang Yating 
Published: August 2020

PurposeThe purpose of this study is to investigate the impact of high-performance (HP) human resource (HR) practices on employee job engagement and organizational citizenship behavior (OCB) and the moderating effects of transformational leadership.Design/methodology/approachA sample of 268 employees from the US and a sample of 288 employees from South Korea (SK) were used for examining the hypotheses.FindingsThe results illustrated that high-performance HR practices (HPHRP) significantly predicted employee job engagement and OCB in SK. Transformational leadership was found to moderate the associations of HPHRP with employee job engagement and OCB in SK, while in the US, transformational leadership only moderated the relationship between HPHRP and OCB.Practical implicationsTransformational leaders reinforce the quality of the employee–organization relationship and strengthen the impact of HPHRP on employees' positive work-related behaviors.Originality/valueThis study contributes to the understanding of employees' organizational behavior as exploring the relationships of HPHRP, transformational leadership, job engagement and OCB.
Aspergillus spp. eliminate Sclerotinia sclerotiorum by imbalancing the ambient oxalic acid concentration and parasitizing its sclerotia
Authors: Atallah Osama , Yassin Sherene 
Published: August 2020

SummarySclerotinia sclerotiorum, a pathogen of more than 600 host plants, secretes oxalic acid to regulate the ambient acidity and provide conducive environment for pathogenicity and reproduction. Few Aspergillus spp. were previously proposed as potential biocontrol agents for S. sclerotiorum as they deteriorate sclerotia and prevent pathogen's overwintering and initial infections. We studied the nature of physical and biochemical interactions between Aspergillus and Sclerotinia. Aspergillus species inhibited sclerotial germination as they colonized its rind layer. However, Aspergillus‐infested sclerotia remain solid and viable for vegetative and carpogenic germination, indicating that Aspergillus infestation is superficial. Aspergillus spp. of section Nigri (Aspergillus japonicus and Aspergillus niger) were also capable of suppressing sclerotial formation by S. sclerotiorum on agar plates. Their culture filtrate contained high levels of oxalic, citric and glutaric acids comparing to the other Aspergillus spp. tested. Exogenous supplementation of oxalic acid altered growth and reproduction of S. sclerotiorum at low concentrations. Inhibitory concentrations of oxalic acid displayed lower pH values comparing to their parallel concentrations of other organic acids. Thus, S. sclerotiorum growth and reproduction are sensitive to the ambient oxalic acid fluctuations and the environmental acidity. Together, Aspergillus species parasitize colonies of Sclerotinia and prevent sclerotial formation through their acidic secretions.
Variability in cesarean delivery rates among individual labor and delivery nurses compared to physicians at three attribution time points
Authors: Edmonds Joyce K. , Weiseth Amber , Neal Brandon J. , Woodbury Samuel R. , Miller Kate , Souter Vivenne , Shah Neel T. 
Published: August 2020

AbstractObjectiveTo examine the variability in the cesarean delivery (CD) rates of individual labor and delivery nurses compared with physicians at three attribution time points.Data SourcesMedical record data from nine hospitals in Washington State from January 2016 through September 2018.Study DesignRetrospective, observational cohort design using an aggregated database of birth records.Data Collection/Extraction MethodsChart‐abstracted clinical data from a subset of nulliparous, term, singleton, vertex births attributed at admission, labor management, and delivery to nurses and physicians. Two classification methods were used to categorize nurse‐ and physician‐level CD rates at three attribution time points and the reliability of these methods compared.Principal FindingsThe sample included 12 556 births, 319 nurses, and 126 physicians. Overall, variation in nurse‐level CD rates did not differ significantly across the three attribution time points, and the extent of variation was similar to that observed in physicians. However, agreement between attribution time points varied between 35 percent and 65 percent when classifying individual nurses into the top and bottom deciles. The average reliability of nurse‐level CD rates was 32 percent at admission (IQR 22.0 percent to 38.7 percent), 32.6 percent at labor (IQR 23.1 percent to 40.9 percent), and 29.3 percent (IQR 20.9 percent to 35.8 percent) at delivery. The average reliability of physician‐level CD rates was higher: 54.2 percent (IQR 38.7 percent to 71.4 percent) at admission, 62.5 percent (IQR 49.0 percent to 79.6 percent) at labor management, and 66.1 percent (IQR 53.7 percent to 81.2 percent) at delivery.ConclusionFeedback on nurse‐level CD rates as part of routine clinical quality audits can provide insight into nurse performance in the context of other individual‐level and unit‐level information. To reliably distinguish individual nurse performance, larger sample sizes are needed.
Risk of malignancy in Korean patients with primary Sjögren's syndrome
Authors: Kang Juyeon , Kim Hyoungyoung , Kim Jinwook , Choi Seongmi , Jung Sun‐Young , Jang Eun Jin , Cho Soo‐Kyung , Sung Yoon‐Kyoung 
Published: August 2020

AbstractObjectivesTo evaluate the risks of overall and site‐specific malignancies in Korean patients with primary Sjögren's syndrome (pSS).MethodsUsing the Korean nationwide healthcare claims database, we constructed a retrospective cohort for prevalent pSS aged over 50 years. After enrollment between January 2012 and December 2014, patients were followed until the development of any malignancy, or until December 2015. Crude incidence rates of malignancies of pSS patients were calculated, and their standardized incidence ratios (SIRs) for malignancies were calculated compared to those in knee osteoarthritis (OA) patients.ResultsA total of 6,359 pSS and 5,476,302 knee OA patients were included in this study. During follow‐up (19,474 person‐years [PYs]), 310 cases of solid malignancy (158.8/10,000 PYs) and 47 cases of hematologic malignancies (23.5/10,000 PYs) were observed in pSS patients. The risks of overall (SIR 1.30, 95% CI 1.16‐1.43), solid (SIR 1.16, 95% CI 1.03‐1.29), and hematologic malignancies (SIR 4.80, 95% CI 3.43‐6.17) were increased in pSS patients. There was an elevated risk of site‐specific malignancy in non‐Hodgkin's lymphoma (NHL, SIR 6.45, 95% CI 4.05‐8.83), multiple myeloma (SIR 4.88, 95% CI 2.00‐7.76), and oropharynx (SIR 4.16, 95% CI 1.90‐6.42). The risk of lung cancer was increased only in male pSS patients (2.50, 95% CI 1.02‐3.99), while the risk of thyroid cancer was increased in female patients (1.44, 95% CI 1.04, 1.84).ConclusionIn patients with pSS over age 50, the risk of solid cancers such as oropharynx, thyroid, and lung cancers is also increased in addition to NHL.
Retracted: Long non‐coding RNA TP73‐AS1 facilitates progression and radioresistance in lung cancer cells by the miR‐216a‐5p/CUL4B axis with exosome involvement
Authors: Qiu Huibing , Zhang Lingyun , Yi Tienan , Yang Kai , Gong Yan , Xie Conghua 
Published: August 2020

Retraction: Qiu, H., Zhang, L., Yi, T., Yang, K., Gong, Y. and Xie, C. (2020), Long non‐coding RNA TP73‐AS1 facilitates progression and radioresistance in lung cancer cells by the miR‐216a‐5p/CUL4B axis with exosome involvement. Thorac Cancer. https://doi.org/10.1111/1759-7714.13602The above article, published online on 25 August 2020 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement among the authors, the journal Editor in Chief Qinghua Zhou, and John Wiley & Sons Ltd. The retraction has been agreed after the results reported in Figures 3B, 3C, 3I, and 3J were found to be not repeatable in authors' further study.
Environmental factors, human presence and prey interact to explain patterns of tiger presence in Eastern Thailand
Authors: Ash E. , Kaszta Ż. , Noochdumrong A. , Redford T. , Macdonald D. W. 
Published: August 2020

AbstractThailand is one of the last strongholds for tigers Panthera tigris in mainland Southeast Asia. Evidence suggests heterogeneity in tiger presence in a globally important landscape in Eastern Thailand is potentially influenced by a complex interaction of prey, human presence and environmental conditions. Understanding these dynamics is of considerable importance for the conservation of tigers both in this landscape and elsewhere in their range. In this study, we examine which factors, among prey, human presence and environmental characteristics, best explain tiger presence in the Dong Phayayen–Khao Yai Forest Complex (DPKY). We collated survey data from 56,214 camera trap nights and evaluated the relationship between tiger presence and a suite of five prey, 11 human presence and eight environmental variables. We then used variance partitioning to discern the degree of variance in tiger presence explained by these factors. We documented strong, positive associations with wild boar Sus scrofa presence and prey richness, and strong, negative associations with human settlement density, public roads and presence of poachers. Environmental characteristics explained a greater relative proportion of variance (19.6%) in tiger presence than prey covariates alone (3.1%), particularly confounded with human presence (31.1%). This suggests that environmental variables, especially when accompanied by anthropogenic factors, could be used to model potential tiger occurrence where other data may be lacking. Our approach may be helpful in providing guidance for prioritizing habitat, evaluating the effect of human presence and identifying key prey to provide a foundation for tiger protection and recovery.
Automated conservation assessment of the orchid family with deep learning
Authors: Zizka Alexander , Silvestro Daniele , Vitt Pati , Knight Tiffany M. 
Published: August 2020

AbstractInternational Union for Conservation of Nature (IUCN) Red List assessments are essential for prioritizing conservation needs but are resource intensive and therefore available only for a fraction of global species richness. Automated conservation assessments based on digitally available geographic occurrence records can be a rapid alternative, but it is unclear how reliable these assessments are. We conducted automated conservation assessments for 13,910 species (47.3% of the known species in the family) of the diverse and globally distributed orchid family (Orchidaceae), for which most species (13,049) were previously unassessed by IUCN. We used a novel method based on a deep neural network (IUC‐NN). We identified 4,342 orchid species (31.2% of the evaluated species) as possibly threatened with extinction (equivalent to IUCN categories critically endangered [CR], endangered [EN], or vulnerable [VU]) and Madagascar, East Africa, Southeast Asia, and several oceanic islands as priority areas for orchid conservation. Orchidaceae provided a model with which to test the sensitivity of automated assessment methods to problems with data availability, data quality, and geographic sampling bias. The IUC‐NN identified possibly threatened species with an accuracy of 84.3%, with significantly lower geographic evaluation bias relative to the IUCN Red List and was robust even when data availability was low and there were geographic errors in the input data. Overall, our results demonstrate that automated assessments have an important role to play in identifying species at the greatest risk of extinction.
To dispense or not to dispense: Lessons to be learnt from ethical challenges faced by pharmacists in the COVID‐19 pandemic
Authors: Cox Shereen 
Published: August 2020

AbstractThe year 2020 is facing one of the worst public health situations in decades. The world is experiencing a pandemic that has triggered significant challenges to healthcare systems in both high and low‐middle income countries (LMICs). Government policymakers and healthcare personnel are experiencing real‐life ethical dilemmas and are pressed to respond to these situations. Many possible treatments are being investigated, one of which is the use of hydroxychloroquine or chloroquine. These drugs are approved for use by patients with systemic lupus erythematosus (SLE), rheumatoid arthritis, and malaria. The demand for these products has increased, and the stocks are depleting for the patient population for whom the drugs are intended initially. Although both innovator and generic pharmaceutical manufacturers are making plans for increased production, there are challenges with global supply chains disruption and the retention of supplies for local markets. This may cause countries that rely on the importation of pharmaceuticals to be out of stock of supplies for an extended period. There are allegations of off‐label prescribing and hoarding. Pharmacists are the custodians and dispensers of medications and are faced with the task of assessing prescriptions and making decisions about the allocation of these products. This paper seeks to 1) highlight some of the ethical challenges of dispensing hydroxychloroquine by pharmacists during the COVID‐19 pandemic, 2) identify some of the responses to these issues from various regulatory authorities in the USA, and 3) recommend approaches to assist pharmacists in their decision‐making process, especially in LMICs.