bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti‐inflammatory effect of fermented brown rice and rice bran with Aspergillus oryzae on mice
Authors: Umeyama Lin , Kasahara Shiori , Sugawara Misa , Yokoyama Satoru , Saiki Ikuo , Hayakawa Yoshihiro 
Published: December 2020

AbstractAimIn this study, we examined the anti‐inflammatory effect of fermented brown rice and rice bran with Aspergillus oryzae (FBRA) on acute and chronic inflammation mouse models.MethodsAs an acute inflammation model, we used a 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA)‐induced ear edema model. As a chronic inflammation model, we used an imiquimod (IMQ)‐induced psoriasis model and ragweed pollen‐induced allergic rhinitis model. We also investigated the effect of FBRA on the expression of inflammatory mediators in skin biopsies from the imiquimod‐induced psoriasis model.ResultsThe mice fed the 10% FBRA‐containing diet showed lower‐level inflammation among the three different experimental models. In the IMQ‐induced psoriasis model, mRNA expressions of IL‐17A, IL‐1β and COX‐2 were significantly inhibited in the skin tissue of mice fed 10% FBRA diet.ConclusionOur data suggest the potential benefit of FBRA as a functional food to prevent excessive inflammation.
The Critical Imperative: Evidence‐Based Practices to Strengthen Leadership Development
Authors: Dugan John P. , Randolph Patrick , Hightower Christian , Rossetti Ana M. 
Published: December 2020

AbstractUsing the Aspen Young Leaders Fellowship as a case study, the authors assert that leadership educators have a responsibility to apply critical perspectives to their work with evidence‐based practice, which involves interrogating assumptions as well as reconstructing pedagogical and design practices to increase equity in leadership education.
Effects of a Δ-9-fatty acid desaturase and a cyclopropane-fatty acid synthase from the novel psychrophile Pseudomonas sp. B14-6 on bacterial membrane properties
Authors: Choi Tae-Rim , Park Ye-Lim , Song Hun-Suk , Lee Sun Mi , Park Sol Lee , Lee Hye Soo , Kim Hyun-Joong , Bhatia Shashi Kant , Gurav Ranjit , Lee Yoo Kyung , Sung Changmin , Yang Yung-Hun 
Published: December 2020

Abstract
Psychrophilic bacteria, living at low and mild temperatures, can contribute significantly to our understanding of microbial responses to temperature, markedly occurring in the bacterial membrane. Here, a newly isolated strain, Pseudomonas sp. B14-6, was found to dynamically change its unsaturated fatty acid and cyclic fatty acid content depending on temperature which was revealed by phospholipid fatty acid (PLFA) analysis. Genome sequencing yielded the sequences of the genes Δ-9-fatty acid desaturase (desA) and cyclopropane-fatty acid-acyl-phospholipid synthase (cfa). Overexpression of desA in Escherichia coli led to an increase in the levels of unsaturated fatty acids, resulting in decreased membrane hydrophobicity and increased fluidity. Cfa proteins from different species were all found to promote bacterial growth, despite their sequence diversity. In conclusion, PLFA analysis and genome sequencing unraveled the temperature-related behavior of Pseudomonas sp. B14-6 and the functions of two membrane-related enzymes. Our results shed new light on temperature-dependent microbial behaviors and might allow to predict the consequences of global warming on microbial communities.
Higher-Order PLS-PM Approach for Different Types of Constructs
Authors: Crocetta Corrado , Antonucci Laura , Cataldo Rosanna , Galasso Roberto , Grassia Maria Gabriella , Lauro Carlo Natale , Marino Marina 
Published: December 2020

AbstractPartial least squares path modeling (PLS-PM) has become very popular in recent years, for measuring concepts that depend on different aspects and that are based on different types of relationships. PLS-PM represents a useful tool to explore relationships and to analyze the influence of the different aspects on the complex phenomenon analyzed. In particular, the use of higher-order constructs has allowed researchers to extend the application of PLS-PM to more advanced and complex models. In this work, our attention is focused on higher-order constructs that include reflective or formative relationships. Even if the dispute between formative models and reflective models is not exactly recent, it is still alive in current literature, for the most part within the context of structural equation models. This paper focuses attention on theoretical and mathematical differences between formative and reflective measurement models within the context of the PLS-PM approach. A simulation study is proposed in order to show how these approaches fit well in different modeling situations. The approaches have been compared using empirical application in a sustainability context. The findings from the simulation and the empirical application can help researchers to estimate and to use the higher-order PLS-PM approach in reflective and formative type models.
Quasielastic Neutron Scattering and Molecular Dynamics Simulation Study on the Molecular Behaviour of Catechol in Zeolite Beta
Authors: Hernandez-Tamargo Carlos , Silverwood Ian P. , O’Malley Alexander J. , Leeuw Nora H. de 
Published: December 2020

AbstractThe dynamics of catechol in zeolite Beta was studied using quesielastic neutron scattering (QENS) experiments and molecular dynamics simulations at 393 K, to understand the behaviour of phenolic monomers relevant in the catalytic conversion of lignin via metal nanoparticles supported on zeolites. Compared to previous work studying phenol, both methods observe that the presence of the second OH group in catechol can hinder mobility significantly, as explained by stronger hydrogen-bonding interactions between catechol and the Brønsted sites of the zeolite. The instrumental timescale of the QENS experiment allows us to probe rotational motion, and the catechol motions are best fit to an isotropic rotation model with a $$D^{rot}$$

D

rot

of 2.9 × 10$$^{10}$$

10

s$$^{-1}$$

-
1

. While this $$D^{rot}$$

D

rot

is within error of that measured for phenol, the fraction of molecules immobile on the instrumental timescale is found to be significantly higher for catechol. The MD simulations also exhibit this increased in ‘immobility’, showing that the long-range translational diffusion coefficients of catechol are lower than phenol by a factor of 7 in acidic zeolite Beta, and a factor of $$\sim$$
∼
3 in the siliceous material, further illustrating the significance of Brønsted site H-bonding. Upon reproducing QENS observables from our simulations to probe rotational motions, a combination of two isotropic rotations was found to fit the MD-calculated EISF; one corresponds to the free rotation of catechol in the pore system of the zeolite, while the second rotation is used to approximate a restricted and rapid “rattling”, consistent with molecules anchored to the acid sites through their OH groups, the motion of which is too rapid to be observed by experiment.
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Authors: Zhao Houli , Wang Yiyun , Yin Elaine Tan Su , Zhao Kui , Hu Yongxian , Huang He 
Published: December 2020

AbstractThe combination of the immunotherapy (i.e., the use of monoclonal antibodies) and the conventional chemotherapy increases the long-term survival of patients with lymphoma. However, for patients with relapsed or treatment-resistant lymphoma, a novel treatment approach is urgently needed. Chimeric antigen receptor T (CAR-T) cells were introduced as a treatment for these patients. Based on recent clinical data, approximately 50% of patients with relapsed or refractory B-cell lymphoma achieved complete remission after receiving the CD19 CAR-T cell therapy. Moreover, clinical data revealed that some patients remained in remission for more than two years after the CAR-T cell therapy. Other than the CD19-targeted CAR-T, the novel target antigens, such as CD20, CD22, CD30, and CD37, which were greatly expressed on lymphoma cells, were studied under preclinical and clinical evaluations for use in the treatment of lymphoma. Nonetheless, the CAR-T therapy was usually associated with potentially lethal adverse effects, such as the cytokine release syndrome and the neurotoxicity. Therefore, optimizing the structure of CAR, creating new drugs, and combining CAR-T cell therapy with stem cell transplantation are potential solutions to increase the effectiveness of treatment and reduce the toxicity in patients with lymphoma after the CAR-T cell therapy.
Synthesis of highly active Cu(I)-Y(III)-Y zeolite and its selective adsorption desulfurization performance in presence of xylene isomers
Authors: Jiang Bo-Long , Jiang Nan , Chang You-Xin 
Published: December 2020

Abstract
Abstract
A bimetal-exchanged NaY zeolite (Cu(I)-Y(III)-Y) with a desirable adsorptive desulfurization (ADS) performance was prepared and characterized by means of X-ray diffraction, specific surface area measurements, X-ray fluorescence spectrometer, X-ray photoelectron spectroscopy, thermal gravity analysis and Fourier transform infrared spectroscopy. The effect of Y(III) ions on ADS in the presence of the xylenes was investigated. Results indicated that the ADS performance of Y(III)-Y is higher than that of most reported CeY. The Y(III)-based Cu(I)-Y(III)-Y demonstrated the higher breakthrough loading than those of reported Ce(III)/Ce(IV)-based transition metal Y zeolites, showing that Y(III) ions play a promoting role in improving the ADS selectivity. For Cu(I)-Y(III)-Y, a new strong S-M interaction (S stands for sulfur, while M stands for metal) active site was formed, which might be caused by the synergistic effect between Cu(I) and Y(III). The Cu(I)-Y(III)-Y, which combined the advantages of Cu(I)-Y and Y(III)-Y, is a kind of promising adsorbent. The breakthrough loading decreased in the order of Cu(I)-Y(III)-Y > Y(III)-Y > Cu(I)-Y, and the effect of xylene isomers on the sulfur removal was in the order of ortho-xylene > meta-xylene > para-xylene, which exhibited the same trend with the bond order of xylenes.
Understanding Collaboration with Virtual Assistants – The Role of Social Identity and the Extended Self
Authors: Mirbabaie Milad , Stieglitz Stefan , Brünker Felix , Hofeditz Lennart , Ross Björn , Frick Nicholas R. J. 
Published: December 2020

AbstractOrganizations introduce virtual assistants (VAs) to support employees with work-related tasks. VAs can increase the success of teamwork and thus become an integral part of the daily work life. However, the effect of VAs on virtual teams remains unclear. While social identity theory describes the identification of employees with team members and the continued existence of a group identity, the concept of the extended self refers to the incorporation of possessions into one’s sense of self. This raises the question of which approach applies to VAs as teammates. The article extends the IS literature by examining the impact of VAs on individuals and teams and updates the knowledge on social identity and the extended self by deploying VAs in a collaborative setting. Using a laboratory experiment with N = 50, two groups were compared in solving a task, where one group was assisted by a VA, while the other was supported by a person. Results highlight that employees who identify VAs as part of their extended self are more likely to identify with team members and vice versa. The two aspects are thus combined into the proposed construct of virtually extended identification explaining the relationships of collaboration with VAs. This study contributes to the understanding on the influence of the extended self and social identity on collaboration with VAs. Practitioners are able to assess how VAs improve collaboration and teamwork in mixed teams in organizations.
Organisationsstruktur und Führungsstil nach Akquisitionen – eine empirische Untersuchung
Authors: Kretschmer Tobias , Dehne Christoph 
Published: December 2020

ZusammenfassungViele Akquisitionen bleiben hinter den in sie gesetzten Erwartungen zurück. Ein Grund hierfür kann sein, dass Synergien nur dann realisiert werden, wenn der Akquisition ein erfolgreicher Post-Merger-Integrationsprozess folgt, der häufig Veränderungen in der Organisationsstruktur und im Führungsstil impliziert. Anhand einer Stichprobe von 230 europäischen Unternehmen untersuchen wir die Tendenz der akquirierten Unternehmen, die Organisationsstruktur und den Führungsstil des akquirierenden Unternehmens zu übernehmen. Unsere Ergebnisse zeigen, dass Veränderungen hauptsächlich im akquirierten Unternehmen stattfinden und dass Veränderungen im Führungsstil oft durch Änderungen der Unternehmensstruktur bedingt werden.
Averting Expenditures and Willingness to Pay for Electricity Supply Reliability
Authors: Niroomand Naghmeh , Jenkins Glenn P. 
Published: December 2020

AbstractNepal has suffered from the worst electricity shortages in South Asia. This study is an attempt to measure the willingness to pay for an improved service using a model of revealed preference. Respondents are asked about the actions they are taking to reduce the impact on their household or business of scheduled and unscheduled outages and more stable voltage. We estimate the averting expenditures that were being incurred to compensate for the lack of reliability of the electricity service. The estimated cost of the averting actions as a percentage of the electricity bills is 53 % for households, 47 % for small businesses, 46 % for medium businesses, and 35 % for large businesses. Based on the estimations, we find that in 2017 the annual benefit from improving the reliability of the electricity service would be approximately US$ 188 million with a present value over 20 years of US$ 1.6 billion.
The effect of type of ventilation used in the operating room and surgical site infection: A meta-analysis
Authors: Bao Jian , Li Jianhua 
Published: December 2020

AbstractsBackground:The relation between type of ventilation used in the operating room and surgical site infection has drawn considerable attention with its conflicting results. A possible relationship between the type of ventilation used in the operating room and surgical site infection has been reported. This meta-analysis was performed to evaluate this relationship.Methods:A systematic literature search up to May 2020 identified 14 studies with 590,121 operations, 328,183 operations of which were performed under laminar airflow ventilation and 261,938 of which were performed operations under conventional ventilation. These articles reported relationships between type of operating-room ventilation with its different categories and surgical site infection: 10 studies were related to surgical site infection in the total hip replacement; 7 studies in total knee arthroplasties; and 3 studies in different abdominal and open vascular surgery. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated comparing surgical site infection prevalence and type of operating room ventilation using the dichotomous method with a random-effects or fixed-effects model.Results:No significant difference was found between operation performed under laminar airflow ventilation and conventional ventilation in total hip replacement (OR, 1.23; 95% CI, 0.97–1.56, P = .09), in total knee arthroplasties (OR, 1.14; 95% CI, 0.62–2.09; P = .67), and in different abdominal and open vascular surgery (OR, 0.75; 95% CI, 0.43-1.33; P = .33). The impact of the type of operating room ventilation may have no influence on surgical site infection as a tool for decreasing its occurrence.Conclusions:Based on this meta-analysis, operating under laminar airflow or conventional ventilation may have no independent relationship with the risk of surgical site infection. This relationship forces us not to recommend the use of laminar airflow ventilation because it has a much higher cost compared to conventional ventilation.
NOTES ON THE K-RATIONAL DISTANCE PROBLEM
Authors: THO NGUYEN XUAN 
Published: December 2020

AbstractLet K be an algebraic number field. We investigate the K-rational distance problem and prove that there are infinitely many nonisomorphic cubic number fields and a number field of degree n for every

$n\geq 2$
in which there is a point in the plane of a unit square at K-rational distances from the four vertices of the square.
ON PROBLEMS OF
-CONNECTED GRAPHS FOR
Authors: STAŠ MICHAL , VALISKA JURAJ 
Published: December 2020

AbstractA connected graph G is

$\mathcal {CF}$
-connected if there is a path between every pair of vertices with no crossing on its edges for each optimal drawing of G. We conjecture that a complete bipartite graph

$K_{m,n}$
is

$\mathcal {CF}$
-connected if and only if it does not contain a subgraph of

$K_{3,6}$
or

$K_{4,4}$
. We establish the validity of this conjecture for all complete bipartite graphs

$K_{m,n}$
for any

$m,n$
with

$\min \{m,n\}\leq 6$
, and conditionally for

$m,n\geq 7$
on the assumption of Zarankiewicz’s conjecture that

$\mathrm {cr}(K_{m,n})=\big \lfloor \frac {m}{2} \big \rfloor \big \lfloor \frac {m-1}{2} \big \rfloor \big \lfloor \frac {n}{2} \big \rfloor \big \lfloor \frac {n-1}{2} \big \rfloor $
.
ACYLINDRICAL HYPERBOLICITY OF ARTIN–TITS GROUPS ASSOCIATED WITH TRIANGLE-FREE GRAPHS AND CONES OVER SQUARE-FREE BIPARTITE GRAPHS
Authors: KATO MOTOKO , OGUNI SHIN-ICHI 
Published: December 2020

AbstractIt is conjectured that the central quotient of any irreducible Artin–Tits group is either virtually cyclic or acylindrically hyperbolic. We prove this conjecture for Artin–Tits groups that are known to be CAT(0) groups by a result of Brady and McCammond, that is, Artin–Tits groups associated with graphs having no 3-cycles and Artin–Tits groups of almost large type associated with graphs admitting appropriate directions. In particular, the latter family contains Artin–Tits groups of large type associated with cones over square-free bipartite graphs.
Molecular characterization of Polychromophilus parasites of Scotophilus kuhlii bats in Thailand
Authors: Chumnandee Chatree , Pha-obnga Nawarat , Werb Oskar , Matuschewski Kai , Schaer Juliane 
Published: December 2020

AbstractParasites of the haemosporidian genus Polychromophilus have exclusively been described in bats. These parasites belong to the diverse group of malaria parasites, and Polychromophilus presents the only haemosporidian taxon that infects mammalian hosts in tropical as well as in temperate climate zones. This study provides the first information of Polychromophilus parasites in the lesser Asiatic yellow bat (Scotophilus kuhlii) in Thailand, a common vespertilionid bat species distributed in South and Southeast Asia. The gametocyte blood stages of the parasites could not be assigned to a described morphospecies and molecular analysis revealed that these parasites might represent a distinct Polychromophilus species. In contrast to Plasmodium species, Polychromophilus parasites do not multiply in red blood cells and, thus, do not cause the clinical symptoms of malaria. Parasitological and molecular investigation of haemosporidian parasites of wildlife, such as the neglected genus Polychromophilus, will contribute to a better understanding of the evolution of malaria parasites.
Long-term trends in helminth infections of wood mice (Apodemus sylvaticus) from the vicinity of Malham Tarn in North Yorkshire, England
Authors: Behnke Jerzy M. , Rogan Michael T. , Craig Philip S. , Jackson Joseph A. , Hide Geoff 
Published: December 2020

AbstractHelminth infections in wood mice (n= 483), trapped over a period of 26 years in the woods surrounding Malham Tarn in North Yorkshire, were analysed. Although 10 species of helminths were identified, the overall mean species richness was 1.01 species/mouse indicating that the helminth community was relatively depauperate in this wood mouse population. The dominant species wasHeligmosomoides polygyrus, the prevalence (64.6%) and abundance (10.4 worms/mouse) of which declined significantly over the study period. Because of the dominance of this species, analyses of higher taxa (combined helminths and combined nematodes) also revealed significantly declining values for prevalence, although not abundance. Helminth species richness (HSR) and Brillouin's index of diversity (BID) did not show covariance with year, neither did those remaining species whose overall prevalence exceeded 5% (Syphacia stroma,Aonchotheca murissylvaticiandPlagiorchis muris). Significant age effects were detected for the prevalence and abundance of all higher taxa,H. polygyrusandP. muris, and for HSR and BID, reflecting the accumulation of helminths with increasing host age. Only two cases of sex bias were found; male bias in abundance ofP. murisand combined Digenea. We discuss the significance of these results and hypothesize about the underlying causes.
Alexis de Tocqueville's Reluctant “Democratic Language”
Authors: Gerçek Salih Emre 
Published: December 2020

AbstractMany readers of Alexis de Tocqueville have noted the ambiguity in his formulation of the term “democracy.” This essay suggests that this ambiguity can be clarified by considering what Tocqueville calls “democratic language”—i.e., the use of generalizations, abstractions, and personifications in writing and speech. Tocqueville investigates these novel linguistic devices to understand the transformation of language in democratic times. More importantly, he employs them to appropriate the Doctrinaires’ formulation of democracy and to criticize their legitimation of the July Monarchy's exclusive government. Yet Tocqueville's use of democratic language is a reluctant one. He finds that the tendency to use abstract and personified concepts obfuscates the political agency of citizens. Wary of the despotic effects of such obfuscation, Tocqueville argues that individuals must practice their concepts. In the context of the July Monarchy, this becomes a call for the extension of democratic rights and institutions.
Investigating the correlation between students’ perception of authenticity in assessment and their academic achievement in the associated assessment tasks
Authors: Ghosh Samrat , Brooks Benjamin , Ranmuthugala Dev , Bowles Marcus 
Published: December 2020

AbstractThe objective of this research was to investigate the factors of assessment that students undergoing authentic assessment perceived to be significant regarding their academic achievement. This project advanced past research by the authors which found that the academic achievement of seafarer students was significantly higher in a formatively implemented authentic assessment compared with a summative traditional assessment. The academic achievement (assessment scores) was based on the students’ performance in analysing information presented in a real-world context (authentic assessment) as opposed to the analysis of information presented devoid of a real-world context (traditional assessment). Using the data obtained from students undergoing the authentic assessment, this project correlated their perceptions of authenticity for factors of assessment to their scores in the associated task. Stage 1 focused on deriving the factors conceptually from the definition of the authentic assessment by the authors, based on which a perception survey questionnaire was designed. Stage 2 extracted new factors through a factor analysis conducted using the software SPSS. Both stages of investigation found that the factor of transparency of criteria was a significant predictor of the students’ academic achievement.