bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations of polyphenolic compounds consumption and the risk of dyslipidemia in the Siberian population
Authors: Batluk T. I. , Denisova D. V. , Berezovikova I. P. , Sherbakova L. V. , Malyutina S. K. , Ragino Y. I. 
Published: June 2020

Aim. To identify associations of polyphenols consumption in general, as well as their classes with the risk of dyslipidemia in the population of Novosibirsk aged 45-69.Material and methods. In 2003-2005, in the frames of the HAPIEE international project “Determinants of cardiovascular diseases in Eastern Europe: a multicenter cohort study” the population sample aged 45-69 (9360 people, 4266 men and 5094 women, average age - 57.6 years) was examined in Novosibirsk. For the analysis of nutrition, a Food Frequency Questionnaire (FFQ) was used (141 product names). The content of polyphenolic compounds and their classes was evaluated using the European database Phenol-Explorer 3.6. The eating habits of the population and typically consumed foods were taken into account. The determination of total cholesterol and HDL cholesterol levels were carried out by enzymatic method. Hypercholesterolemia was diagnosed with cholesterol level greater than 5.0 mmol/l (190 mg/dL). Levels of HDL cholesterol <1.0 mmol/l in men and <1.2 mmol/l in women were considered as high-density lipoprotein hypocholesterolemia (hypoHDL-C). The concentration of low-density lipoprotein cholesterol was calculated with the Friedewald formula (1972). HyperLDL-C was diagnosed if level of LDL cholesterol was <3.0 mmol / l.Results. The chance of developing of hypercholesterolemia in the quartile with the highest consumption of “other polyphenols” was 20% less (OR 1.2 confidence interval (CI 1.01-0.14), p = 0.033), phenolic acids by 20% (OR 1.2 (CI 1.01-1.42), p = 0.04) and stilbenes by 37% (OR 1.37 (CI 1.15-1.64), p = 0.001) less than in the quartile of low consumption. The risk of developing hypoHDL-C was lower in the quartile of high polyphenols consumption in general by 18% (OR 1.18 (CI 1.002-1.4), p = 0.051), phenolic acids by 32% (OR 1.32 (CI 1.11-1.57), p = 0.001) and the groups of “other polyphenols” by 20% (OR 1.2 (CI 1.01-1.41), p = 0.04). The chance of hyperLDL-C in the high quartile of consumption of “other polyphenols” decreased by 16% (OR 1.16 (CI 1.002-1.355), p = 0.049) and lignans - by 33% (OR 1.33 (CI 1.14-1, 56), p <0.001) compared with low consumption.Conclusion. Thus, the consumption of polyphenols in general and in classes (phenolic acids, stilbenes, and “other polyphenols”) decreased the risk of dyslipidemia in Siberian population.
TAKAYASU ARTERİTİNDE TEK MERKEZ DENEYİMİ
Authors: LİMON Muhammet , TEZCAN Dilek , GÜLCEMAL Semral , YILMAZ Sema 
Published: June 2020

Giriş-Amaç: Takayasu arteriti(TA), etyolojisi tam olarak bilinmeyen aorta ve ana
dalları olmak üzere büyük damarları etkileyen kronik granülomatöz büyük damar
vaskülitidir. Bu çalışma ile kliniğimizde takip edilen TA sıklığı ve tedavi cevapları
değerlendirilmiştir. Gereç-Yöntem: Bu çalışma retrospektif olarak Ocak
2016-Ekim 2019 arasında Romatoloji Bilim Dalında yapıldı. Çalışmaya 18 yaş
üzeri 1990 Amerika Romatoloji Cemiyeti Kriterlerine göre TA tanısı konulan 20
hasta dahil edildi. Bulgular: Kliniğimizde retrospektif
olarak değerlendirilen 20 tane TA hastasının 17 tanesi kadın, 3 tanesi
erkekti. Hastaların yaş ortalaması 38,2
olarak bulundu. TA’lı hastaların ortalama sedimantasyon: 34 mm/s, CRP: 16 mg/L
olarak bulundu. RF ve ANCA bütün hastalarda negatif bulundu. TA’ya bağlı
vasküler tutulum değerlendirildiğinde %90 sıklıkta subklavian arter, %50
karotis arter, %40 abdominal aorta, %35 torasik aorta, %15 renal arter tutulumu
gözlendi. Medikal tedavide %100 kortikosteroid, %55 siklofosfamid, %45 metotreksat,
%25 azatioprin, %5 leflunomid, %5 tosilizumab kullanıldığı gözlendi. Geleneksel
tedavi (metotreksat, azatioprin, leflunomid) ile %45 hastanın remisyonda
olduğu, %10 hastanın dirençli olması nedeniyle siklofosfamid verildiği görüldü.
Hastaların %45’inde yaygın damar tutuluşu nedeniyle siklofosfamid ve kortikosteroid
kombinasyonu ilk tedavi olarak tercih edildiği görüldü. Siklofosfamid tedavisi
alan hastaların idamesinde sırayla %25
infliksimab,%15 metotreksat,%10 azatioprin, %5 metotreksat ve azatioprin verilmiştir.Tartışma-Sonuç: Bu çalışmada TA’lı
hastaların demografik, klinik, anjiografik bulguları
ve medikal tedavi yanıtları değerlendirilmiştir. TA’nın demografik, klinik ve
anjiografi bulguları literatür ile uyumlu bulunmuştur. TA’nın medikal
tedavisinde kortikosteroidler ve metotreksat, azatioprin, leflunomid gibi geleneksel
tedaviler verilir. Geleneksel tedavilere dirençli olgularda anti-TNF, IL-6
blokeri verildiği gözlenmiştir.
Avaliação da Topografia de Superfície e Microdureza de Resinas Acrílicas e uma Resina Bisacrílica Submetidas a Diferentes Técnicas de Polimento
Authors: Santana de Ávila Eduardo Lima , Dos Reis Goyatá Luís Felipe , Almeida Simões Thamyryz Rafaela , Moreira Lanza Celia , Batista Novaes Júnior João , Moreno Amália , Talma Elissa , Barreiros Doche Ivan , Dos Reis Goyatá Frederico 
Published: June 2020

Introdução: As resinas acrílicas são indicadas principalmente para a confecção de restaurações provisórias em prótese parcial fixa. Este trabalho tem por objetivo verificar a influência de diferentes sistemas de polimento sobre a topografia de superfície e a microdureza de três resinas acrílicas: Dencôr, Dencrilay Speed, Duralay e uma resina bisacrílica: Proviplast.
Metodologia: Foram confeccionados 140 corpos de prova com uma matriz cilíndrica de silicone de dimensões de 5 x 2 mm (ISSO 4872) que foram distribuídos em quatorze grupos teste, de acordo com o polimento (n:10): ECS – escova de Carbeto de Silício, PBD – pontas de borracha impregnadas por diamante, PD – pasta diamantada e GL: aplicação do glaze. Os valores de rugosidade (Ra), Microscopia de Força Atômica (MFA) e Microdureza (Ma) foram obtidos antes e após polimento realizado com os sistemas descritos.
Resultados: Os dados obtidos no estudo foram tabulados e analisados por ANOVA e o teste “t” de Student 5% (α = 0,05). Os valores de rugosidade variaram entre 0,05 e 6,2 µm sendo que a resina bisacrílica com glaze apresentou a menor média de rugosidade (0,05) e Dencrilay sem polimento apresentou o maior valor (6,2). Os valores de microdureza variaram entre 23,3 e 11,6 onde o Duralay com borracha abrasiva apresentou a maior média de microdureza (23,3) e Duralay com pasta o menor valor (11,6). Dentre os materiais testados, a resina bisacrílica com glaze obteve o menor valor de rugosidade de superfície e a resina Duralay com borracha obteve o maior valor de microdureza.
La coautoría impropia en los delitos comunes
Authors: Sánchez-Pérez Claudia Patricia 
Published: June 2020

Propósito: el presente artículo de reflexión se centra en el concurso de personas en la comisión de la conducta punible; se dice que cuando el hecho delictivo es realizado por varias personas, resulta esencial identificar el grado de responsabilidad penal que le corresponde a cada una, según su aporte, se analizará específicamente la figura del coautor impropio en los delitos comunes. Descripción: se describen las causas, consecuencias y salidas jurídicas para quienes intervienen en la comisión de la conducta punible según su grado de responsabilidad, evitando a usanza por la Fiscalía la formulación de cargos con penas exacerbadas. Punto de vista: aunque existen elementos jurídicos, doctrinales y jurisprudenciales válidos para lograr hacer las distinciones acertadas sobre el grado de responsabilidad por la intervención en la comisión de conductas punibles, estos no se hacen valer por la agencia fiscal o por el abogado en su rol de defensor, aceptando formulación de cargos sin la verificación de cada uno de los elementos que estructuran la coautoría impropia. Conclusiones: partiendo de los elementos estructurales de la coautoría impropia y de la interpretación de sus contenidos según la ley, la doctrina y la jurisprudencia sobre el dominio funcional del hecho y el concepto restrictivo de autor, se colige que tener en cuenta los parámetros ya establecidos, al momento de diferenciar la coautoría impropia de otras formas de participación, especialmente de la del cómplice, deriva en la formulación de cargos y el merecimiento de penas proporcionales a la participación real de una persona en la comisión de la conducta punible.
Ineficacia de la acción de repetición en el municipio de Florencia, Caquetá. Estudio de caso, 2010-2016
Authors: Bustos Ortega Juan Sebastián , Rosas Sánchez Carlos Javier 
Published: June 2020

Propósito: el propósito del presente escrito es establecer la eficacia de la acción de repetición y con ello determinar el impacto del medio de control en la recuperación dineraria invertida para el pago de sentencias judiciales en el municipio de Florencia, Caquetá, en el periodo 2010-2016.
Metodología: para lograr este objetivo, se planteó una investigación básica, con un tipo de estudio descriptivo, bajo el método de investigación deductivo, consultando fuentes estadísticas y valiéndose de la sistematización de datos para su análisis como técnica de recolección de información.
Hallazgos: la responsabilidad civil extracontractual es una de las garantías propias de los Estados modernos, con la cual se busca dotar a la sociedad de mecanismos para ejercer el pago de indemnizaciones con ocasión a la conducta de los funcionarios públicos; por tanto, se han implementado en nuestra normatividad acciones o medios de control como mecanismos procesales habilitantes para solicitar el resarcimiento del perjuicio.
Conclusiones: en el municipio de Florencia, Caquetá, la eficacia de la acción de repetición en las vigencias 2010-2016 es nula, la Alcaldía tan solo ha iniciado tres acciones de las cuales una se archivó, frente a un total de 89 condenas en contra del municipio.
Desarrollo y validación de la Escala de Evaluación Cognitiva de la Infidelidad (ECI) para muestras colombianas
Authors: Riveros Munívar Fernando , Veloza Tello Valentina , Pedraza María alejandra 
Published: June 2020

Objetivo: El presente estudio de tipo instrumental tuvo como objetivo diseñar y validar una escala cuya finalidad es evaluar la percepción de las personas frente a las cuatro dimensiones de la infidelidad–sexual, emocional, cognitiva y virtual–, a través de dos subdimensiones de la cognición –motivos y consecuencias–
Método: Para ello se realizó una tabla de especificaciones y se construyeron los ítems, los cuales fueron sometidos a validación por jueces. Se realizó el ajuste a la escala y esta fue aplicada a una muestra voluntaria de 301 participantes con edades entre los 18 y 70 años ( = 29.84; DE = 14.07), y que además contaran con habilidades cognitivas básicas de comprensión lectora.
Resultados: Tras realizar el análisis factorial exploratorio, se encontraron siete factores que explican el 48,64% de la varianza total acumulada, y el índice de extracción permitió la conservación de todos los ítems, modelo factorial confirmado, con adecuados niveles de bondad de ajuste (CFI = .910; RMSEA = .049). Además de ello, con el Alfa de Cronbach general de .84 se evidenció una alta confiabilidad de la escala y con un coeficiente de dos mitades de Guttman de .87 se encontró una fuerte relación entre dos mitades.
Conclusión: la Escala de Evaluación Cognitiva de Infidelidad es un instrumento pionero que permite evaluar con criterios de validez y confiabilidad el fenómeno de la infidelidad.
Hypovitaminosis D is Associated with Psoriasis: A Systematic Review and Meta- Analysis
Authors: Pitukweerakul Siwadon , Thavaraputta Subhanudh , Prachuapthunyachart Sittichoke , Karnchanasorn Rudruidee 
Published: June 2020

Introduction
Psoriasis is a chronic inflammatory and immunemediatedskin disease that affects over 7.2 million U.S. adults. Currenttreatment has improved clinical outcomes. Vitamin D is believed toaffect the proliferation and regeneration of keratinocytes; therefore,its deficiency is a possible risk factor; however, there is still no definiteevidence. The objective of this study was to synthesize existing dataon the relationship between hypovitaminosis D and psoriasis.
Methods.
A meta-analysis of relevant studies was conducted bydoing a comprehensive search in the MEDLINE, EMBASE, and theCochrane Central Register through July 2018 to identify relevantcohort studies and to assess serum 25-hydroxyvitamin D (25(OH)D) levels in adults with psoriasis. The primary outcome was the meandifference in serum 25(OH)D level between psoriatic patients andcontrols.
Results
The initial search identified 107 articles. Only ten studiesmet the criteria for full-paper review. Meta-analysis was conductedfrom ten prospective cohort studies involving 6,217 controls and 693cases. The pooled mean difference in serum 25(OH)D level betweenpsoriatic patients and controls was -6.13 ng/ml (95% CI, -10.93 to-1.32, p-value = 0.01). The between-study heterogeneity (I2) was98%, p < 0.00001.
Conclusion
Our meta-analysis was the first study to establish therelation between vitamin D and psoriasis. The result found a significantrelationship between low 25(OH) D levels and psoriasis, but didnot establish a causal relationship. Further studies will be requiredto establish whether vitamin D supplementation benefits patientswith psoriasis.
The Early “Unnatural” History Following Surgical Repair of Ventricular Septal Defects
Authors: Chikkabyrappa Sathish M. , Tretter Justin T. , Doshi Arpan R. , Buddhe Sujatha , Bhatla Puneet , Ludomirsky Achi 
Published: June 2020

Introduction
Surgical outcomes for simple ventricular septaldefects (VSD) have been excellent in the past three decades. Forthis project, the timing of resolution of left-sided dilation and mitralregurgitation (MR) following VSD repair was assessed.
Methods
Echocardiographic data surrounding surgery of 42 consecutivechildren who underwent surgical patch repair of a VSD werereviewed. The echocardiograms were reviewed up to a mean of 12months post-operatively (range 9 - 14 months). Quantitative dataindexed to body surface area including left atrial (LA) volume, mitralvalve annulus diameter, and left ventricular end-diastolic dimension(LVEDD) was analyzed.
Results
The majority of our pre-surgical cohort had only trace(44%) or no MR (31%), with a small proportion having mild (16%)or moderate MR (9%). No patients had moderate or greater MR followingrepair at follow-up. The median mitral valve annular Z-scorewas 1.8 (SD 1.6; range: -1.2 to 4.1) pre-operatively, improving to a 0.6(range: -1.7 to 2.4; p < 0.001) at follow-up. LA dilation was present in70% of patients, with a median LA volume Z-score of 1.1 (range: -2.6to 15.5), decreasing to 13% median Z-score -1.2 (range: -3.5 to 2.9; p< 0.001) at follow-up. LV dilation was present in 81% of pre-operativepatients with a median LVEDD Z-score of 3.0 (range: -2.0 to 7.9).There was significant improvement in qualitative assessment of LVenlargement (25%) with a median LVEDD Z-score of 0.5 (range:-2.1 to 2.9; p < 0.001) at follow-up. Discharge echocardiogram wasperformed at a mean of 5.7 days (range: 3 - 12 days) following surgery.
Conclusions
Normalization of LA, mitral valve annulus, and LV sizeoccurred within the first three months in the majority of patients, withsignificant changes occurring within the first post-operative weekfollowing surgical repair for VSD.
Incidence of Gunshot Wounds: Before and After Implementation of a Shall Issue Conceal Carry Law
Authors: Nicholas Christina , Ward Jeanette , Helmer Stephen , Haan James 
Published: June 2020

Introduction. This study examined the incidence of gunshot wounds before and after enacting a conceal carry (CC) law in a predominately rural state.
Methods. A retrospective review was conducted of all patients who were admitted with a gunshot injury to a Level I trauma center. Patient data collected included demographics, injury details, hospital course, and discharge destination.
Results. Among the 238 patients included, 44.6% (n = 107) were admitted during the pre-CC period and 55.4% (n = 131) in the post-CC period. No demographic differences were noted between the two periods except for an increase in uninsured patients from 43.0% vs 61.1% (p = 0.020). Compared to pre-CC patients, post-CC patients experienced a trend toward increased abdominal injury (11.2% vs 20.6%, p = 0.051) and increased vascular injuries (11.2% vs 22.1%, p = 0.026) while lower extremity injuries decreased significantly (38.3% vs 26.0%, p = 0.041). Positive focused assessment with sonography in trauma (FAST) exams (2.2% vs 16.8, p < 0.001), intensive care unit admission (26.2% vs 42.0%, p = 0.011) and need for ventilator support (11.2% vs 22.1%, p = 0.026) all increased during the post-CC period. In-hospital mortality more than doubled (8.4% vs 18.3%, p = 0.028) across the pre- and post-CC time periods.
Conclusion. Implementation of a CC law was not associated with a decrease in the overall number of penetrating injuries or a decrease in mortality.
Urine Screening for Opiod and Illicit Drugs in the Total Joint Arthroplasty Population
Authors: Vopat Matthew , Messamore William , Trent Jesse , Schmanke Ken , Zackula Rosey , Yang Shang-You , Bhargava Tarun 
Published: June 2020

Introduction. Recent studies have shown an increase in post-operative orthopaedic complications associated with pre-operative opioid use. It is, therefore, important to know if patients use opioids before scheduled surgery. The purpose of this study was to determine if urine drug screening (UDS) is an effective screening tool for detecting opioid and illicit drug use prior to joint arthroplasty (JA) procedures.
Methods. This retrospective chart review was performed with IRB approval on 166 out of 172 consecutive patients in a community-based practice. All the patients had a pre-operative UDS prior to primary or revision JA by a fellowship trained orthopaedic surgeon between March 2016 and April 2017. Patient demographics documented opioid and illicit drug use, co-morbid diagnosis, and UDS results were collected from clinical charts. Statistical analysis was conducted using Pearson Chi-square, Fisher’s exact, McNemar test, and t-tests with IBM SPSS Statistics, ver. 23. Significant differences were p < 0.05.
Results. Sixty-four of 166 patients (38.6%) tested positive for opioids. Among them, 55.0% (35/64) had no history of prescription opioid use. Significant differences were observed when comparing the test results of the UDS with the patient reported history of prescribed opioids (p = 0.001).
Conclusion. With a significant number of patients testing positive for opioids without evidence of a previous prescription, UDS may be beneficial for initial risk assessment for patients undergoing JA procedures.
Los caminos de William Christian
Authors: Medeiros Antònio 
Published: June 2020

Oí hablar de William Christian por primera vez en los años ochenta, cuando era estudiante en Lisboa y andaba leyendo Person and God. Entonces, me contaron que su autor era un americano de pelo largo, un independent scholar que recorría España con su moto. Yo había visto Easy Rider y durante muchos años me lo imaginé con esa referencia, poco ajustada, como enseguida se comprobará… En 2013 una amiga me dijo que, si quería conocer al muy reservado Bill Christian, debería asistir a una conferencia suya que tendría lugar en pocos días en la Universidad Autónoma de Madrid. Asistí, y desde entonces hemos hablado en varias ocasiones, en Madrid, en Lisboa, en Las Palmas y por Skype… De esas conversaciones resulta esta aproximación biográfica.
DOCENTES DE TECNOLOGIA DA INFORMAÇÃO E COMUNICAÇÃO
Authors: Possato Alvaro Bubola , Monteiro Patrícia Ortiz 
Published: June 2020

O objetivo do trabalho é fazer uma análise sobre como os docentes do ensino profissionalizante, da área de tecnologia da informação e comunicação (TDIC), fazem uso das tecnologias. O projeto do qual se origina o presente artigo se mostra relevante porque a compreensão de como esse profissional trabalha com as TDIC pode melhorar o seu desempenho profissional e suas relações, assim como fornecer subsídios que poderão contribuir para as suas práticas. Essa pesquisa – descritiva, exploratória, com abordagem qualitativa – utilizou como instrumento a entrevista semiestruturada, aplicada a 16 (dezesseis) professores de uma instituição de ensino, em duas cidades do Vale do Paraíba paulista. Para a análise dos dados coletados foi utilizado o software IRAMUTEQ, de domínio livre, e foram encontradas 5 classes de análise. O desenvolvimento da análise do conteúdo foi sistematizado pela teoria apresentada por Bardin (2011). A análise dos dados aponta que o docente faz uso das TDIC em sala de aula, utilizando-as para a maioria dos afazeres da prática docente; que os docentes de TDIC estão em constante trabalho de atualização, tendo a internet como principal base de busca; e que tal atualização se faz necessária, pois as TDIC evoluem e mudam constantemente. Para tanto, em conformidade com a identidade institucional a que pertencem, os docentes passam por processos de “certificação” que os habilitam a exercer a docência de TDIC de forma qualificada.
RELEVANCIA DEL POLIMORFISMO DE ELIMINACIÓN DEL GEN GSTM1 Y GSTT1 EN PACIENTES CON NEFRITIS LUPICA
Authors: Garrido Baza Jorge , Rojano Rada Jairo , Fernández Mestre Mercedes 
Published: June 2020

Objetivo: Identificar si la ausencia de los genes GSTM1 y/o GSTT1 está correlacionada con la respuesta a ciclofosfamida y con la presencia de anti DNA en paciente con LES. Metodología: Estudio transversal correlacional, que incluyó 46 pacientes con diagnóstico de lupus eritematoso sistémico (LES), que acudieron a la consulta de reumatología del Instituto Venezolano del Seguro Sociales- Hospital Central “Dr. Miguel Pérez Carreño”, durante el período septiembre 2016 – junio de 2017. Los pacientes con LES se clasificaron de acuerdo a la presencia o no de afectación renal (nefritis lúpica). A cada individuo se le extrajo 5 mL de sangre periférica, a partir de la cual se extrajo el ADN genómico. La presencia o ausencia de los genes GSTM1 y GSTT1 se determinó utilizando el método de reacción en cadena de la polimerasa múltiplex con iniciadores específicos. Resultados: En la población estudiada (n= 46), 95,7% eran mujeres y sólo 4,3% hombres. La edad media fue de 31 años, siendo en su mayoría mujeres jóvenes en edad fértil. El tratamiento de los pacientes, comprendió el uso de cloroquina (78%), micofenolato (69,6 %) y corticoides (38,7%). Los genes GST estuvieron presentes, el gen GSTM1 con una frecuencia del 100 % y GSTT1 del 93,5%. Solo un 6,5% de los pacientes no presentaron el gen GSTT1. Conclusión: No se observó una correlación entre la presencia y/o ausencia de los genes GSTM1 y GSTT1 con la respuesta al tratamiento con Ciclofosfamida ni a la presencia de anti-DNA