bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geoarchaeological investigations at the Ryan‐Harley Paleoindian site, Florida (8JE1004): Implications for human settlement of the Wacissa River Basin during the Younger Dryas
Authors: Smith Morgan F. 
Published: April 2020

AbstractRyan‐Harley (8JE1004) in the Wacissa River of North Florida is one of few sites in the Eastern United States that contains an unfluted lanceolate point component (Suwannee) in a buried context. Extinct and extirpated faunal remains found within the Suwannee artifact layer at Ryan‐Harley have been cited as evidence of a Pleistocene faunal refugium in the Southeastern United States. In 2015, geoarchaeological excavations were undertaken to determine if the Ryan‐Harley Suwannee assemblage is culturally discrete and associated with Pleistocene fauna. Geoarchaeological data demonstrate that the archaeological component was exposed until ~8,000 calbp on a relict eolian landscape before burial. No radiocarbon ages were obtained on either extinct or extant faunal material from the site, and the excavated portion of the geologic stratum containing the artifact assemblage is devoid of other datable organics. Therefore, no unequivocal conclusion can be reached about the association of the extinct faunal material with the Suwannee artifacts. However, multiple lines of evidence fail to reject the hypothesis that the Ryan‐Harley lithic assemblage represents a single occupation of Suwannee point makers. Multiple lines of evidence suggest that the Suwannee occupation of Ryan‐Harley most likely occurred during the Younger Dryas (~12,900–11,700 calbp).
The potential of vegetation indices: estimating methane emissions in paddy fields under nighttime warming and water saving conditions
Authors: Zhen Zhang , Yunsheng Lou , Rui Li , Li Ma , Jun Li , Amina Lukali 
Published: April 2020

AbstractNondestructive and rapid methods for estimating methane emissions from paddy fields are helpful in indentifying options for emission mitigation, both at global and local scales. However, few studies have used an approach of vegetation indices for estimating methane emissions in paddy fields from ground‐based hyperspectral data. Therefore, this study systematically analyzed the quantitative relationship of methane emissions from rice fields to hyperspectral vegetation indices based on hyperspectral reflectance data of rice canopy. A field experiment was designed with two nighttime warming levels, that is, nighttime warming and control (ambient temperature), and two irrigation levels, that is, flooding (control, with 5 cm depth of water layer) and wetting (water saving irrigation, without water layer). Results showed that the newly developed three‐band index (R1139 − R960)/(R1139 + R960 − 2R944) (Rλ is the reflectance value at wavelength λ) was recommended as the optimal index for monitoring methane emission from paddy field, generated coefficients of determination, root mean square error, and residual prediction deviation values between the measured and predicted values of 0.687, 1.424 mg m−2 h−1, and 1.83, respectively. This study provides a theoretical basis and technical support for methane emissions assessment in paddy fields based on vegetation indices. © 2020 Society of Chemical Industry and John Wiley & Sons, Ltd.
Estimating bed material fluxes upstream and downstream of a controlled large bifurcation ‐ the Mississippi‐Atchafalaya River diversion
Authors: Wang Bo , Xu Yi‐Jun 
Published: April 2020

AbstractBed material transport at river bifurcations is crucial for channel stability and downstream geomorphic dynamics. However, measurements of bed material transport at bifurcations of large alluvial rivers are difficult to make, and standard estimates based on the assumption of proportional partitioning of flow and bedload transport at bifurcations may be erroneous. In this study, we employed a combined approach based on observed topographic change (erosion/deposition) and bed material transport predicted from a one‐dimensional model to investigate bed material fluxes near the engineering‐controlled Mississippi‐Atchafalaya River diversion, which is of great importance to sediment distribution and delivery to Louisiana's coast. Yang's (1973) sediment transport equation was utilized to estimate daily bed material loads upstream, downstream, and through the diversion during 2004–2013. Bathymetric changes in these channels were assessed with single beam data collected in 2004 and 2013. Results show that over the study period, 24% of the Mississippi River flow was diverted into the Atchafalaya River, while the rest remained in the mainstem Mississippi. Upstream of the diversion, the bed material yield was predicted to be 201 million metric tons (MT), of which approximately 35 MT (i.e., 17%) passed through the bifurcation channel to the Atchafalaya River. The findings from this study reveal that in the mainstem Mississippi, the percentage of bed material diversion (83%) is larger than the percentage of flow diversion (76%); Conversely, the diversion channel receives a disproportionate amount of flow (24%) relative to bed material supply (17%). Consequently, severe bed scouring occurred in the controlled Outflow Channel to the Atchafalaya River, while riverbed aggradation progressed in the mainstem Mississippi downstream of the diversion structures, implying reduced flow capacity and potential risk of a high backwater during megafloods. The study demonstrates that Yang's sediment transport equation provides plausible results of bed material fluxes for a highly complicated large river diversion, and that integration of the sediment transport equation with observed morphological changes in riverbed is a valuable approach to investigate sediment dynamics at controlled river bifurcations.
Psychometric properties and measurement invariance of Depression, Anxiety and Stress Scales (DASS‐21) across cultures
Authors: Bibi Akhtar , Lin Muyu , Zhang Xiao Chi , Margraf Jürgen 
Published: April 2020

Cross‐culturally measurement invariant instruments are useful for the assessment of mental symptoms across cultures. The current study aimed to investigate the psychometric properties and measurement invariance of the Depression, Anxiety and Stress Scales (DASS‐21) (DASS) across Pakistan and Germany. German participants were recruited through an online survey (N = 1323), while Pakistani participants were recruited through online survey or paper‐and‐pencil survey (N = 1841). The DASS‐21 showed good reliability, construct and structure validity in both countries. The DASS‐21 indicated partial weak (stress subscale) and partial strong measurement invariance (depression and anxiety subscales) between both countries. Latent mean comparison of depression and anxiety symptoms between Pakistani and German students indicated that Pakistani university students experience more symptoms of depression and anxiety. Results suggest that the DASS‐21 could be used in Pakistan and Germany, but caution should be taken when making direct comparisons between the two countries.
Avoiding the fatal misdiagnosis of pregnancy in a noncommunicating rudimentary horn using 3D transvaginal ultrasound
Authors: Walker Christopher , Collins Laura , Pham Amanda , George Joshua , Johnson Samuel 
Published: April 2020

AbstractRudimentary horn pregnancies are an increasingly recognized complication of Mullerian duct anomalies. They can lead to uterine rupture with severe maternal morbidity and mortality. We present the case of a 28‐year‐old woman with a prior surgical diagnosis of bicornuate uterus who was diagnosed with a 7‐week pregnancy in the left horn of a bicornuate uterus by 2D ultrasound. Further investigation with 3D ultrasound revealed that the pregnancy was within a noncommunicating rudimentary horn of a unicornuate uterus. These findings were confirmed at laparotomy. This case illustrates the importance and benefits of utilizing 3D ultrasound in diagnosing suspected Mullerian anomalies.
Synthesize of β‐cyclodextrin functionalized dendritic fibrous nanosilica and its application for the removal of organic dye (malachite green)
Authors: Abbasvash Leila , Shadjou Nasrin 
Published: April 2020

AbstractDye removal from industrial waste water has become an important issue. The highvisibility, undesirability and recalcitrance are the significant environmental problemfor the dyes. In the present work,β‐cyclodextrin functionalized KCC‐1 (KCC‐1‐NH‐β‐CD)was synthesized and utilized to the removal of hazardous malachite green. In order to study the morphology of the synthesized nano adsorbent, Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) were obtained from the surface of the sample. Additionally, the functionalization of KCC‐1 with β‐cyclodextrin was confirmed with Furrier Transform Infrared spectroscopy (FTIR). The textural property of KCC‐1 was verified using nitrogen adsorption/ desorption analysis (BET equation). UV‐Vis spectroscopy utilized for the investigation of malachite green by KCC‐1‐NH‐β‐CD. Specific surface area of the adsorbent was calculated to be 140 m2/g and it can be stated that the synthesized nano adsorbent has high removal efficiency. It should be noted that the adsorption capacity of the employed nano adsorbent was more than 95%, which could be attributed to high porosity of β‐cyclodextrin functionalized KCC‐1.
The aim of the measurement of Epstein‐Barr virus DNA in hydroa vacciniforme and hypersensitivity to mosquito bites
Authors: Miyake Tomoko , Iwatsuki Keiji , Hirai Yoji , Yamamoto Takenobu , Hamada Toshihisa , Fujii Kazuyasu , Imamura Hideaki , Morizane Shin 
Published: April 2020

AbstractEpstein‐Barr virus (EBV) DNA load in the blood increases in posttransplant lymphoproliferative disorders and chronic active EBV infection. In this report, we analyzed the EBV DNA load in the peripheral blood mononuclear cells (PBMCs) and plasma of patients with hydroa vacciniforme (HV) and/or hypersensitivity to mosquito bites (HMB) to understand the clinical significance of EBV DNA load. All 30 patients showed high DNA loads in the PBMCs over the cut‐off level. Of 16 plasma samples, extremely high in two samples obtained from patients with hemophagocytic lymphohistiocytosis (HLH). The amount of cell‐free DNA in plasma was correlated to the serum levels of lactate dehydrogenase and inversely correlated to platelet counts. These results indicate that the EBV DNA load in PBMCs can provide one of the diagnostic indicators for HV and HMB and marked elevation of cell‐free EBV DNA in plasma might be related to cytolysis such as that observed in HLH.
Was the extremely wet winter of 2018/2019 in the lower reach of the Yangtze River driven by El Niño–Southern Oscillation?
Authors: Liu Yunyun , Hu Zeng‐Zhen , Wu Renguang 
Published: April 2020

AbstractIn the winter of 2018/2019, the lower reach of the Yangtze River (LRYR) of China experienced an excessive amount of precipitation with a long duration. Such an extreme event occurred in the mature phase of an El Niño under the background of global warming, and thus, attracted great attention in the society and climate community. Presumably, this extreme event was driven by the El Niño. In this work, based on observational diagnoses and real‐time model forecasts, we investigate the contributions of oceanic forcing and the predictability of this event. It is argued that tropical Atlantic warming, interdecadal variation, and central tropical Pacific warming (associated with Central Pacific [CP] instead of Eastern Pacific El Niño) are three major factors leading to the extreme event. In addition to the recognized impact from sea surface temperature anomalies (SSTAs) associated with CP El Niño, tropical Atlantic warming makes an important contribution to the Atlantic‐Eurasian circulation change through a global zonal wave pattern extending from the tropical Atlantic to East Asia. Moreover, a climate model successfully predicted the wet pattern in LRYR in short (1–5 month) lead real‐time predictions, and captured the observed statistical relationship between the winter precipitation in LRYR and the SSTA in the central tropical Pacific and equatorial Atlantic Oceans. These results indicate that such an event is predictable to some extent.
Theoretical Approaches on the Synergistic Interaction between Double‐Headed Anionic Amino Acid‐Based Surfactants and Hexadecyltrimethylammonium Bromide
Authors: Barai Manas , Mandal Manas Kumar , Sultana Habiba , Manna Emili , Das Sourav , Nag Kaushik , Ghosh Soumen , Patra Anuttam , Panda Amiya Kumar 
Published: April 2020

AbstractTheoretical investigations on the micellization of mixtures of (i) amino acid‐based anionic surfactants [AAS: N‐dodecyl derivatives of aminomalonate, −aspartate, and ‐glutamate] and (ii) hexadecyltrimethylammonium bromide (HTAB), were carried out at different mole ratios. Variation in the theoretical values of critical micelle concentration (CMC), mole fraction of surfactants in the micellar phase (X), at the interface (Xσ), interaction parameters at the bulk/interface (βR/βσ), ideality/nonideality of the mixing processes, and activity coefficients (f) were evaluated using Rubingh, Rosen, Motomora, and Sarmoria‐Puvvada‐Blankschtein models. CMC values significantly deviate from the theroretically calculated values, indicating associative interaction. With increasing mole fraction of AAS (αAAS), the magnitude of the (βR/βσ) values gradually decreased, considered to attributable to hydrophobic interactions. With increasing αAAS, the micellar mole fraction of HTAB (X2) decreased insignificantly and X2 values were higher than those compared to AAS for all combinations, due to the dominance of HTAB in micelles. Micellar mole fraction at the ideal state of AAS () differed from micellar mole fraction of AAS (X1), indicating nonideality in the mixed micellization process. Gibbs free energy of micellization (
∆Gm) values are more negative than the free energy of micellization for ideal mixing (), indicating the micellization process is spontaneous. With increasing αAAS, the enthalpy of micellization (ΔHm) and entropy of micellization (ΔSm) values gradually increased, which indicates micellization is exothermic. The different physicochemical parameters of the mixed micelles are correlated with the variation in the spacer length between the two carboxylate groups of AAS.
Flexible OLED display with 620°C LTPS TFT and touch sensor manufactured by weak bonding method
Authors: Ke Tsung‐Ying , Kang Ting , Lee Chih‐Tsung , Chen Chun‐Yu , Su Wei‐Jen , Wang Wen‐Ting , Huang Zih‐Shuo , Wang Jen‐Chih , Hsu Shou‐Te , Wang Cheng‐Liang , Lai Yen‐Huei , Wang Wan‐Tsang , Liu Chun‐Hsin , Lin Kun‐Yu 
Published: April 2020

AbstractBy weak bonding method, the first organic light‐emitting diode (OLED) display with 620°C low‐temperature poly‐silicon (LTPS) thin film transistor (TFT) and touch sensor, without polyimide (PI) substrate, formed on glass substrates is transferred to non‐PI flexible substrates. After transfer, the display image is free from defect, and touch sensor functions normally. Compared with device made on PI substrate, the advantages of device stability and pitch variation by transferring are shown.
Application of aeration‐assisted homogeneous liquid–liquid microextraction procedure using Box–Behnken design for determination of curcumin by HPLC
Authors: Khorshidi Neda , Rahimi Marzieh , Salimikia Iraj 
Published: April 2020

AbstractA simple, efficient, and rapid sample preparation method based on aeration‐assisted homogeneous liquid–liquid microextraction was developed for determination of curcumin in food samples by high‐performance liquid chromatography. The centrifuge step has been eliminated in this procedure. The effects of some variables, such as pH, volume of extraction solvent, extraction time, and salt effect, were studied through a Box–Behnken design method. Under the optimum conditions, calibration curves of curcumin were linear in the range of 0.08‐4000 μg/mL with R2 = 0.997. Limit of detection and relative standard deviation were 0.019 μg/mL and 3.01%, respectively. The preconcentration factor achieved was 166. The proposed method was successfully applied to determination of curcumin in various food samples.
Ultrasound‐Guided Hydrodissection With Corticosteroid Injection in the Treatment of Carpal Tunnel Syndrome
Authors: Schrier Verena J. M. M. , Brault Jeffrey S. , Amadio Peter C. 
Published: April 2020

ObjectivesCorticosteroid injections can provide (temporary) relief in patients with mild to moderate carpal tunnel syndrome (CTS). Hydrodissection as part of an injection has been associated with positive clinical outcomes but data for CTS so far has been scarce. This study is designed to assess patient tolerance and secondarily provide pilot data on the added effect of hydrodissection.MethodsTwenty CTS patients were randomized to an ultrasound‐guided betamethasone injection with hydrodissection (5 mL) or without (2 mL). Patient tolerance was assessed directly after intervention and patient‐reported outcome after 4 and 24 weeks. Intra‐group data were compared using Wilcoxon Signed Rank and inter‐group with Wilcoxon rank‐sum tests.ResultsTolerance and pain scores did not differ between the two groups. Symptom scores decreased in both groups, but to a lesser extent in the hydrodissection group with a mean difference of −0.8 versus −1.5 in the control group at 4 weeks (P = .02). At 6 months, this difference was no longer present (P = .81). No statistically significant differences were found between the hydrodissection and control groups in the function or pain scores at follow‐up at either time point.ConclusionAfter injection, both symptomatic and functional scores improved, but the hydrodissected group did not show additional improvement. Data presented can be used to support larger studies to assess the value of hydrodissection in CTS management.
EMI2 expression as a poor prognostic factor in patients with breast cancer
Authors: Vadhan Anupama , Wang Yen‐Yun , Yuan Shyng‐Shiou F. , Lee Yi‐Chen , Hu Stephen Chu‐Sung , Huang Jyun‐Yuan , Ishikawa Takashi , Hou Ming‐Feng 
Published: April 2020

AbstractEarly mitotic inhibitor 2 (EMI2, gene symbol FBXO43), an APC/C inhibitor regulated by Plx1, is essential for cytostatic factor (CSF) activity. It belongs to subclass FBXO of the F‐box proteins family. The aim of this study is to examine the clinicopathological significance of EMI2 in breast cancer. In this study, immunohistochemistry analysis was used to evaluate EMI2 expression in breast cancer tissues and then the association between EMI2 expression and clinicopathological factors was examined. Correlation of EMI2 with patient survival was analyzed by Kaplan‐Meier survival curves. Among 192 patients analyzed, 105 (54.7%) had high expression of EMI2, and this was significantly associated with shortened disease free survival and overall survival in breast cancer patients. EMI2 expression was significantly associated with tumor grade (P = .006), tumor size (P < .001), and lymph node metastasis (P = .008). However, there was no significant correlation between EMI2 status and other biomarkers including ER, PR and Her2 status. Our results revealed that elevated EMI2 expression is a risk factor (hazard ratio = 3.93) for breast cancer and overexpression of EMI2 in breast cancer predicts higher risk of metastasis and worse survival. Therefore, EMI2 may be a potential therapeutic target for breast cancer.
Measuring engagement in a collaborative learning health system: The case ofImproveCareNow
Authors: Hartley David M. , Keck Christian , Havens Mary , Margolis Peter A. , Seid Michael 
Published: April 2020

AbstractBackgroundCollaborative learning health systems have demonstrated improved outcomes for a range of different chronic conditions. Patient and healthcare provider engagement in these systems is thought to be associated with improved outcomes. We have adapted an observational framework to measure, and track over time, engagement in ImproveCareNow, a collaborative learning health system for children with inflammatory bowel disease.IntroductionWe developed a categorical classification scheme for engagement in ImproveCareNow. Each tier is defined in terms of observable individual behaviors. When an individual completes one or more qualifying behavior, s/he is classified as engaged at that tier. Individuals are entered into a database, which is accessible to care centers throughout the ImproveCareNow network. Database records include fields for individual name, behavior type, time, place, and level of engagement.ResultsThe resulting system is employed at 79 ImproveCareNow care centers in the United States. The system recognizes four levels of engagement. Behaviors are recorded in a managed vocabulary and recorded in an online database. The database is queried weekly for individual engagement behaviors, which are tracked longitudinally. Center‐ and network‐level statistics are generated and disseminated to stakeholders.ConclusionIt is possible to monitor longitudinal engagement in a collaborative learning health system, thereby charting progress toward engagement goals and enabling quantitative evaluation of interventions aimed at increasing engagement.
A protocol for recombinant protein quantification by densitometry
Authors: Alonso Villela Susana María , Kraïem Hazar , Bouhaouala‐Zahar Balkiss , Bideaux Carine , Aceves Lara César Arturo , Fillaudeau Luc 
Published: April 2020

AbstractThe protein purity is generally checked using SDS‐PAGE, where densitometry could be used to quantify the protein bands. In literature, few studies have been reported using image analysis for the quantification of protein in SDS‐PAGE: that is, imaged with Stain‐Free™ technology. This study presents a protocol of image analysis for electrophoresis gels that allows the quantification of unknown proteins using the molecular weight markers as protein standards. Escherichia coli WK6/pHEN6 encoding the bispecific nanobody CH10‐12 engineered by the Pasteur Institute of Tunisia was cultured in a bioreactor and induced with isopropyl β‐D‐1‐thiogalactopyranoside (IPTG) at 28°C for 12 hr. Periplasmic proteins extracted by osmotic shock were purified by immobilized metal affinity chromatography (IMAC). Images of the SDS‐PAGE gels were analyzed using ImageJ, and the lane profiles were obtained in grayscale and uncalibrated optical density. Protein load and peak area were linearly correlated, and optimal image processing was then performed by background subtraction using the rolling ball algorithm with radius size 250 pixels. No brightness and contrast adjustment was applied. The production of the nanobody CH10‐12 was obtained through a fed‐batch strategy and quantified using the band of 50 kDa in the marker as reference for 750 ng of recombinant protein. The molecular weight marker was used as a sole protein standard for protein quantification in SDS‐PAGE gel images.
Green High‐Power Disk Lasers and Industrial Applications
Authors: Tomcic Lazar , Rettich Thomas , Zäh Michael F. 
Published: April 2020

AbstractIn the publicly‐funded ProLasKu project, the laser manufacturer Trumpf has developed a high‐power laser with a wavelength of 515 nm. Substantial progress in the industrial applications of green lasers has been achieved in a cooperation between the Technical University of Munich and the companies Siemens and Continental. In addition, a camera‐based system for process monitoring and quality assurance in real‐time based on image processing methods has been developed.