bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis Of Effectiveness Of Online Learning Pandemic Covid-19 In Prosthetic Orthotic Major In Polkesta
Authors: Rachmat Nur 
Published: November 2020

Background: Prosthetic Orthotics Major in Polkesta conducts online lectures in order to support government efforts in the even semester 2019/2020, starting from March 2020 until the end of the even semester. Several online applications are used in support of online lectures. This study was conducted to analyze the effectiveness of online learning during the covid-19 pandemic in the orthotic prosthetic Major in Polkesta Indonesia. Methods: This is quantitative descriptive study. This research uses survey method using online Google Form questionnaire. The population is students of Prosthetic Orthotic Major, There are 322 respondents who are willing to contribute in the research. Data obtained through filling in questions that are shared with all respondents in the form of google form. Then the collected data was analyzed and described. The components contained in the questionnaire consisted of several questions, namely (1) Do you understand online learning at the time of the Covid-19 Pandemic; (2) Do you think online learning at Prosthetic Orthotic Major Polkesta was effective; (3) Which online application is used for online learning that is effective in your opinion; (4) Which online learning model do you feel effective; (5) Types of assignments that make you understand during online learning; (6) What media do you use when implementing online learning; (7) are there any obstacles when you carry out online learning (8) What obstacles do you face when implementing learning. Results: there are 67 % of students felt less effective, 14% of students felt ineffective, 20 % of students felt effective. Applications used by students and felt to be effective are Google meet, google classroom, WhatsApp Group. Learning methods using Life video conferencing are felt to be the most effective. Conclusion: Online learning process in the prosthetic orthotic major is not felt to be quite effective by students.
Learning Patterns of Online Students
Authors: Thiele Joan E 
Published: November 2020

ABSTRACT
The virtual explosion of online education has prompted questioning of the quality of the learning. In addition, the effect of online learning on learner outcomes is receiving scrutiny. In this study, online students became more independent and selfdisciplined as learners. In addition, the students reported they learned to trust their own judgment and delve deeper into the content than they did in traditional lecture-driven courses. The effect of online courses on learning styles is described.
A Hybrid Grey Wolf Optimizer and Artificial Bee Colony Algorithm Used for Improvement in Resource Allocation System for Cloud Technology
Authors: Ouhame Soukaina , Hadi Youssef , Arifullah Arifullah 
Published: November 2020

Cloud computing is the next generation of technology which provide different service with the rule of pay and gain with the help of internet. These services consist of hardware and software used in different field of life. Due the growth of user in cloud environment the number of access and share system of technology increases which causes different issue and resource allocation system is one of them. In this paper for improvement in resource allocation system in VM a hybrid algorithm used because in some situation VM become underloaded and overloaded in cloud data centre due to lack of proper load balancing technique system. Therefore a hybrid technique used for improvement in VM allocation system. The hybrid technique consist of GWO and ABC algorithm three main section of GWO technique improve first improvment occur at local search section in this section ABC algorithm local search technique used second improvement occur at fitness function along with the energy parameter. The above proposed technique used to improve four main parameter of scheduling which are energy consumption, throughput network stability and average network executation time in resource allocation system in VM for cloud computing. The proposed technique result are compare with ABC algorithm , GWO algorithm, RAA algorithm based on those result the proposed algorithm improve 1.25 % accuracy and efficiency for resource allocation system in VM for cloud computing.
Our Laboratory Experience: Comparison of Capillary Electrophoresis/Immunosubtraction and Agarose Gel/Immunofixation
Authors: Pieri Massimo , Tomassetti Flaminia , Iodice Caterina , Piazzolla Rosa , Riboldi Elena , Capogreco Francesca , Innocenti Adalgisa , Frassanito Maria Loredana , Bernardini Sergio , Calugi Graziella 
Published: November 2020

Abstract. Monoclonal gammopathies represent a wide spectrum of related diseases. The common denominator is the presence of a monoclonal protein in the serum or urine, which can be in the form of intact immunoglobulin, immunoglobulin fragments, and/or free light chains (κ and λ). We can detect these abnormalities by immunofixation electrophoresis (IFE) in which specific antibodies are overlaid after electrophoresis and the corresponding immunoglobulin. In our study, we compared gel-based and capillary-based serum protein electrophoresis methods to identify and characterize monoclonal immunoglobulins in serum samples. We analyzed 500 serum samples by Sebia Hydragel agarose gel electrophoresis (AGE)/immunofixation electrophoresis (IFE) and CAPILLARYS 2 capillary zone electrophoresis (CZE)/immunosubtraction (IS). AGE/IFE and CZE/IS had an overall agreement of 98% on serum protein electrophoresis. In our hands, AGE/IFE and CZE/IS had the same specificity for detection of monoclonal proteins; however, CZE/IS seems to be more sensitive than AGE/IFE for the detection of some critical cases. However, CZE/IS is an analytically suitable alternative to AGE/IFE, although laboratories should need to combine, for singular samples, both electrophoretic methods in their clinical routine. A combined use of AGE/IFE and CZE/IS is necessary to lead to an accurate diagnosis and clinically error-free results.
Uji Stabilitas Fisik Formula Sediaan Gel Ekstrak Daun Kelor (Moringa Oleifera Lamk.)
Authors: Slamet S , Anggun Bibah Dewi , Pambudi Dwi Bagus 
Published: November 2020

Abstrak. Tanaman kelor mempunyai khasiat sebagai antibakteri. Penambahan ekstrak daun kelor (Moringa oleifera Lamk.) di dalam sediaan gel diperkirakan dapat mempengaruhi stabilitas fisik sediaan tersebut. Penelitian ini bertujuan menguji stabilitas fisik sediaan gel yang mengandung ekstrak daun kelor (Moringa oleifera Lamk.) pada berbagai konsentrasi (1%, 3% dan 5%). Uji stabilitas fisik sedian gel dilakukan setelah penyimpanan selama 14 hari pada suhu ruangan dan uji cycling test (2oÂ±40o C). Parameter stabilitas adalah organoleptis, uji daya sebar, uji daya lekat, pH, viskositas dan cycling test. Hasil ketiga formulasi menunjukkan stabilitas yang sesuai persyaratan sediaan gel diuji pada pengamatan organoleptis, daya sebar, daya lekat, pH, viskositas dan hasil uji cycling test.

Kata kunci : Gel, Kelor, Stabilitas Fisik

Physical Stability Test Formula Ready Gel Moringa Leaf Extract (Moringa Oleifera Lamk.)

Abstract. Moringa plants have efficacy as an antibacterial. The addition of moringa leaf extract (Moringa oleifera Lamk.) preparation required to affect the physical stability of the preparation. The study aims to test the physical stability of gel preparations containing Moringa oleifera Lamk. Leaf extract at various concentrations (1%, 3% and 5%). gel formula physical stability test was carried out after storage for 14 days at room temperature and the cycling test (2o Â± 40o C). The stability parameters are organoleptic, dispersion test, adhesion test, pH, viscosity, cycling test. The results of the three formulations showed that stability according to the requirements of the gel preparation. Gel preparation tested on observations of organoleptic, spreadability, adhesion, pH, viscosity, and cycling test results.
Keyword: Gel, Moringa, Physical Stability
CO2 Top-of-Line-Corrosion; Assessing the Role of Acetic Acid on General and Pitting Corrosion
Authors: Folena Mariana Costa , Barker Richard , Pessu Frederick , Ponciano José Antônio da Cunha , Neville Anne 
Published: November 2020

Based on a review of both literature and field data, it is apparent that the role of acetic acid (HAc) in oilfield brines is both extremely complex and somewhat controversial. Although it is commonly believed that the presence of this organic compound enhances both the general and the localized corrosion rate of carbon steel, HAc has recently been reported to also act as a weak general corrosion inhibitor in specific aqueous environments. These observations prompted a study into whether such behavior is apparent in a CO2 top-of-line corrosion (TLC) scenario, i.e., when HAc dissolves into condensed water that forms on the upper internal wall of carbon steel pipelines during wet-gas stratified flow. Four different water condensation rates/temperature TLC conditions were selected to investigate the role of HAc on both the kinetics and mechanism of carbon steel dissolution. A miniature three-electrode setup was developed to characterize the real-time TLC response through the implementation of electrochemical measurements. Surface analysis techniques (microscopy and profilometry) were also performed to complement the electrochemical results. Collective consideration of the corrosion response and condensate chemistry indicates that similar effects were observed to those reported in the literature for bulk aqueous environments, in that the introduction of HAc can result in either accentuation or a minimal/inhibitive effect on general corrosion depending upon the operating conditions. The minimal/inhibitive effects of HAc were apparent at a surface temperature of 20.5°C and water condensation rate of 0.5 mL/m2·s, as no significant increase in corrosion was observed, despite a significant reduction in condensate pH being generated by the presence of HAc. X-ray photo-electron spectroscopy analysis of the inhibited steel specimen in the presence of HAc revealed the presence of iron acetate on the steel surface, which may have been at least partially responsible for the observed inhibitive effect. Extended duration experiments over 96 h revealed that both general and localized corrosion are not significantly affected by HAc addition at low temperature, whereas the level of degradation increases at higher surface temperature over longer periods.
ANALISA KEPUASAN PASIEN DALAM PELAYANAN KESEHATAN DI PUSKESMAS PEMBANTU PARARAPAK KABUPATEN BARITO SELATAN TAHUN 2019
Authors: Ivana Theresia , Taraneti Desi , Permana Luckyta Ibna 
Published: November 2020

Intisari
Latar belakang Puskesmas merupakan fasilitas kesehatan yang menyelenggarakan upaya kesehatan masyarakat dan perseorangan tingkat pertama, dengan mengutamakan upaya promotif dan preventif. Puskesmas merupakan salah satu fasilitas kesehatan yang banyak dimanfaatkan oleh masyarakat. Setiap pelayanan jasa akan berdampak pada kemauan dari pelanggan untuk mendatangi tempat pelayanan dilaksanakan. Kepuasan pelanggan mempengaruhi kunjungan tersebut, sehingga pelayanan kesehatan yang prima menjadi hal yang utama dalam pelayanan kesehatan. Kepuasan pasien berhubungan langsung dengan pelayanan yang diberikan di puskesmas, apabila pemberi layanan melakukan service excellent diharapkan tingkat kepuasan pasien akan meningkat.
Metode Penelitian deskriptif kuantitatif yang bertujuan melakukan analisa kepuasan pasien dalam pelayanan kesehatan di Puskesmas Pembantu Pararapak Kabupaten Barito Selatan tahun 2019. Populasi penelitian 70 orang, jumlah sampel yang didapatkan 45 orang responden yang ditentukan dengan teknik purposive sampling. Variabel tunggal penelitian yaitu kepuasan pasien. Pengambilan data menggunakan kuesioner Service Quality terdiri atas lima dimensi kepuasan
Hasil Kepuasan pasien dalam pelayanan kesehatan di Puskesmas Pembantu Pararapak pada dimensi tangible 71,1% sangat memuaskan, pada dimensi reliability 55,6% puas, dimensi responsiveness 71,1% sangat puas, dimensi assurance 60% sangat puas, dan dimensi empathy 44,4% puas.
Kesimpulan Secara umum kepuasan pasien dalam pelayanan kesehatan di Puskesmas Pembantu Pararapak menunjukkan sangat puas terhadap pelayanan kesehatan yang diperikan di Puskesmas Pembantu Pararapak, Kabupaten Barito Selatan, tahun 2019
Kata kunci Kesehatan, Kepuasan, Pasien, Pelayanan, SERVQUAL
Impacts of the North Atlantic Oscillation on winter precipitations and storm track variability in southeast Canada and the northeast United States
Authors: Chartrand Julien , Pausata Francesco S. R. 
Published: November 2020

Abstract. The North Atlantic Oscillation (NAO) affects atmospheric variability from eastern North America to Europe. Although the link between the NAO and winter precipitations in eastern North America has been the focus of previous work, only few studies have considered extreme precipitation and hitherto provided clear physical explanations on these relationships. In this study we revisit and extend the analysis of the effect of the NAO on mean and heavy winter precipitations over a large domain covering southeast Canada and the northeastern United States. Furthermore, we use the recent ERA5 reanalysis dataset (1979–2018), which currently has the highest available horizontal resolution for a global reanalysis (0.25∘), to track extratropical cyclones to delve into the physical processes behind the relationship between NAO and precipitation, snowfall, snowfall-to-precipitation ratio (S∕P), and snow cover depth anomalies in the region. In particular, our results show that positive NAO phases are associated with less snowfall over a wide region covering Nova Scotia, New England and the Mid-Atlantic of the United States relative to negative NAO phases. Over the same area, the analysis of heavy snowfall revealed that there are up to twice as many heavy snowfall events during negative phases compared to positive phases. Therefore,
a significant negative correlation is also seen between S∕P and the NAO over this region. This is due to a decrease (increase) in cyclogenesis of coastal storms near the United States east coast during positive (negative) NAO phases, as well as a northward (southward) displacement of the mean storm track over North America.
New fossil genus and new extant species of diatoms (Stephanodiscaceae, Bacillariophyceae) from Pleistocene sediments in the Neotropics (Guatemala, Central America): adaptation to a changing environment?
Authors: Paillès Christine , Sylvestre Florence , Tonetto Alain , Mazur Jean-Charles , Conrod Sandrine 
Published: November 2020

Several taxa of Stephanodiscaceae were found in the upper section of Pleistocene sediments from Lake Petén-Itzá (Guatemala). A new fossil genus Cyclocostis Paillès gen. nov. and new extant species Discostella gabinii Paillès & Sylvestre sp. nov. are described. Cyclocostis gen. nov. is characterized by a strongly tangentially undulated valve surface, coarse unequal striation reaching a central punctum in the valve center, an absence of central lamina and domed criba, widely open alveoli with one median recessed costa bearing marginal fultoportulae and a single rimoportula all within a ring. A single valve face fultoportula is present on the raised part of the valve opposite the rimoportula. Differences relative to similar genera and the delimitation of a new genus are discussed. Discostella gabinii sp. nov. is distinguished by circular and flat valves, a small central area bearing 5 to > 30 scattered large areolae giving a colliculate appearance, medium-sized alveoli, marginal fultoportulae on every 4–5th costa, a single rimoportula and internally smooth valve center. Differences to similar taxa in the genus Discostella are discussed. The succession of the species of Cyclotella, Discostella and Cyclocostis gen. nov. in our record could represent eco-phenotypic responses to particular environmental stress / change.
A hybrid method for heartbeat classification via convolutional neural networks, multilayer perceptrons and focal loss
Authors: Wang Tao , Lu Changhua , Yang Mei , Hong Feng , Liu Chun 
Published: November 2020

Background
Heart arrhythmia, as one of the most important cardiovascular diseases (CVDs), has gained wide attention in the past two decades. The article proposes a hybrid method for heartbeat classification via convolutional neural networks, multilayer perceptrons and focal loss.

Methods
In the method, a convolution neural network is used to extract the morphological features. The reason behind this is that the morphological characteristics of patients have inter-patient variations, which makes it difficult to accurately describe using traditional hand-craft ways. Then the extracted morphological features are combined with the RR intervals features and input into the multilayer perceptron for heartbeat classification. The RR intervals features contain the dynamic information of the heartbeat. Furthermore, considering that the heartbeat classes are imbalanced and would lead to the poor performance of minority classes, a focal loss is introduced to resolve the problem in the article.

Results
Tested using the MIT-BIH arrhythmia database, our method achieves an overall positive predictive value of 64.68%, sensitivity of 68.55%, f1-score of 66.09%, and accuracy of 96.27%. Compared with existing works, our method significantly improves the performance of heartbeat classification.

Conclusions
Our method is simple yet effective, which is potentially used for personal automatic heartbeat classification in remote medical monitoring. The source code is provided on https://github.com/JackAndCole/Deep-Neural-Network-For-Heartbeat-Classification.
Effects of platelet-rich plasma on mesenchymal stem cells isolated from rat uterus
Authors: Vishnyakova Polina , Artemova Daria , Elchaninov Andrey , Efendieva Zulfiia , Apolikhina Inna , Sukhikh Gennady , Fatkhudinov Timur 
Published: November 2020

Background
Platelet-rich plasma (PRP), which represents a valuable source of growth factors, is increasingly being applied in regenerative medicine. Recent findings suggest the feasibility of using PRP in the treatment of infertility secondary to refractory thin endometrium. Mesenchymal stem/stromal cells (MSCs) of the endometrium are an essential cellular component responsible for extracellular matrix remodeling, angiogenesis, cell-to-cell communication, and postmenstrual tissue repair. Using a rat model, we examine the effects of autologous PRP on MSCs isolated from the uterus and compare them with the effects of autologous ordinary plasma (OP) and complete growth medium.

Methods
MSCs were isolated from uterine tissues via enzymatic disaggregation. Flow cytometry immunophenotyping of the primary cell cultures was complemented by immunocytochemistry for Ki-67 and vimentin. The ability of MSCs to differentiate in osteo-, chondro-, and adipogenic directions was assessed using differentiation-inducing media. The levels of autophagy and apoptosis markers, as well as the levels of matrix metalloproteinase 9 (MMP9) and estrogen receptor α, were assessed by western blotting.

Results
After 24 h incubation, the proliferation index of the PRP-treated MSC cultures was significantly higher than that of the MSC cultures treated with complete growth medium. PRP treatment elevated production of LC3B protein, an autophagy marker, while OP treatment upregulated the expression of stress-induced protein p53 and extracellular enzyme MMP9. The results indicate practical relevance and validity for PRP use in the treatment of infertility.
Long non‐coding RNA RACGAP1P promotes breast cancer invasion and metastasis via miR‐345‐5p/RACGAP1‐mediated mitochondrial fission
Authors: Zhou Danmei , Ren Kehan , Wang Meili , Wang Jigang , Li Ermin , Hou Chenjian , Su Ying , Jin Yiting , Zou Qiang , Zhou Ping , Liu Xiuping 
Published: November 2020

Long non‐coding RNAs (lncRNAs) are emerging as key molecules in various cancers, yet their potential roles in the pathogenesis of breast cancer are not fully understood. Herein, using microarray analysis, we revealed that the lncRNA RACGAP1P, the pseudogene of Rac GTPase activating protein 1 (RACGAP1), was up‐regulated in breast cancer tissues. Its high expression was confirmed in 25 pairs of breast cancer tissues and 8 breast cell lines by qRT‐PCR. Subsequently, we found that RACGAP1P expression was positively correlated with lymph node metastasis, distant metastasis, TNM stage, and shorter survival time in 102 breast cancer patients. Then, in vitro and in vivo experiments were designed to investigate the biological function and regulatory mechanism of RACGAP1P in breast cancer cell lines. Overexpression of RACGAP1P in MDA‐MB‐231 and MCF7 breast cell lines increased their invasive ability and enhanced their mitochondrial fission. Conversely, inhibition of mitochondrial fission by Mdivi‐1 could reduce the invasive ability of RACGAP1P‐overexpressing cell lines. Furthermore, the promotion of mitochondrial fission by RACGAP1P depended on its competitive binding with miR‐345‐5p against its parental gene RACGAP1, leading to the activation of dynamin‐related protein 1 (Drp1). In conclusion, lncRNA RACGAP1P promotes breast cancer invasion and metastasis via miR‐345‐5p/RACGAP1 pathway‐mediated mitochondrial fission.
ToColdlyGo Where No Grass has Gone Before: A Multidisciplinary Review of Cold Adaptation in Poaceae
Authors: Schubert Marian , Humphreys Aelys M. , Lindberg Camilla Lorange , Preston Jill C. , Fjellheim Siri 
Published: November 2020

AbstractThe grass family Poaceae is among the largest and most successful plant families, both ecologically and economically. It covers a wide geographic, climatic, and ecological range and contains many of the world's most important crops including wheat, barley, rice, maize, and sorghum, as well as many forage and biofuel species. Both wild and cultivated grasses are diverse in areas that regularly experience cold and freezing as well as high seasonality, harsh winters, and short growing seasons. Grasses growing in these environments have evolved an arsenal of strategies to tolerate or resist cold stress, or to escape the cold by phenological adjustments. Here, we review the current knowledge of cold adaptations in grasses synthesising across the disciplines of stress physiology, genetics, metabolomics, ecology, and evolution, in both wild and cultivated species. Specifically, we explore what is known about molecular and physiological cold stress responses, how these might have evolved and their role in shaping diversification and distribution patterns of grasses. We argue that integrating insights from multiple disciplines will further our understanding of cold adaptation.