bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pattern of pulmonary vasculitis and major vascular involvement in Hughes-Stovin syndrome (HSS): brief report of eight cases
Authors: Emad Yasser , Ragab Yasser , Ibrahim Ossama , Saad Ahmed , Rasker Johannes J. 
Published: December 2019

AbstractTo describe the pattern of pulmonary artery vasculitis and the characteristic computed tomographic pulmonary angiography (CTPA) signs in patients with Hughes-Stovin syndrome (HSS). In a retrospective study, the medical records of eight HSS patients (six men), seen between February 2008 and January 2018, were reviewed regarding history, disease characteristics, laboratory investigations, imaging, and treatments. The mean (SD) age was 37.375 ± 8.65 years (range 30–55) and mean (SD) follow-up 30 ± 41.60 months (range 9–132). In all patients, routine laboratory investigations and complete coagulation profile were done. In all, CTPA studies were performed as well as and Doppler ultrasound for suspected deep vein thrombosis (DVT). Four patients had a history of thrombophlebitis, and DVT was observed in all, in two cases bilateral. Arterial thromboses involving popliteal, tibial, common iliac, and femoral arteries were observed in one patient. All patients had mild to moderate hemoptysis, and one had massive hemoptysis. None of the patients had a history of recurrent mouth and/or genital ulcers, uveitis, or arthritis. In all patients, CTPA identified bilateral pulmonary artery aneurysms (PAAs) with adherent in situ thrombosis and mural enhancement in all patients. Lobar PA branches were involved in all patients, segmental in six and main PA in five patients. Proper immunomodulators were initiated early, with favorable outcome; none was treated with TNF-α antagonists. HSS is a systemic vasculitis that may affect virtually all major veins and arteries in patients with normal coagulation profile. PAAs, adherent in situ thrombosis, and mural wall enhancement are characteristic CTPA signs. Early treatment with immunomodulators is essential.Key Points• Hughes Stevin syndrome (HSS) is a systemic vasculitis that may affect virtually all major veins and arteries in patients. It has a normal coagulation profile.• Computed tomography (CT) pulmonary angiography is considered to be the most important diagnostic tool to assess the degree and the extent of the characteristic pulmonary artery aneurysms, and in situ thrombosis, and mural wall enhancement.• It is likely that HSS syndrome is often not recognized and misdiagnosed as deep venous thrombosis (DVT) with pulmonary thromboembolism.• Early treatment with combined immunomodulators is essential to ensure favorable outcome.
Outcomes of a Care Coordination Guardianship Intervention for Adults with Severe Mental Illness: An Interrupted Time Series Analysis
Authors: Levine Eliot , Jett Catherine , Johnson Jeremiah , Connors Heather 
Published: December 2019

AbstractThis study investigates the impacts of an intensive care coordination intervention for adults with severe mental illness who have guardians. Program impacts on medical and legal outcomes were assessed using interrupted time series analysis. Program participation was associated with statistically significant reductions in the level and trend of psychiatric hospitalizations, number of days in psychiatric hospitals, emergency room visits, and arrests. Days incarcerated did not change significantly. The decrease in medical and legal outcomes may be associated with decreased spending on these services. The program and other intensive care coordination interventions for this population warrant further replication and research.
Genetic relationships and hybridization among three western Atlantic sparid species: sheepshead (Archosargus probatocephalus), sea bream (A. rhomboidalis) and pinfish (Lagodon rhomboides)
Authors: Seyoum Seifu , Adams Douglas H. , Matheson Richard E. , Whittington James A. , Alvarez Alicia C. , Sheridan Nancy E. , Panzner Kaitlin , Puchulutegui Cecilia 
Published: December 2019

AbstractThree species of sparids in the western Atlantic, sheepshead (Archosargus probatocephalus), sea bream (A. rhomboidalis), and pinfish (Lagodon rhomboides), share overlapping habitats, spawning seasons, and spawning grounds, providing opportunities for interaction among these species. Three regions of mitochondrial DNA and three nuclear DNA intron sequences were used to construct the genetic relationships among these species. The results showed that these species are closely related, suggesting the presence of soft polytomy with sheepshead and western Atlantic sea bream as sister species. However, western Atlantic sea bream and pinfish are equally divergent from sheepshead. We used a suite of 18 microsatellite markers to verify the occurrence of hybridization, identify the parental types, and evaluate the filial-generation status of 36 individuals morphologically identified as hybrids from the Indian River Lagoon system, in Florida. The 36 putative hybrids were analyzed with a reference group of 172 western Atlantic sea bream, 232 pinfish, and 157 sheepsheads and were all genetically determined to be F1of sheepshead and western Atlantic sea bream with very little indication or no introgressive hybridization among the 172 reference specimens of western Atlantic sea bream. Hybridization was asymmetric, with western Atlantic sea bream males crossing with sheepshead females. Hybrids were first observed in the Indian River Lagoon in 2005, after the western Atlantic sea bream had become common there, in the 1990s. Their occurrence could be associated with unique features of the Indian River Lagoon that bring the two species together or with recent anthropogenic changes in this system. Further study is needed to determine the causes and long-term effects of the recurrent production of F1hybrids and the degree of their sterility in the Indian River Lagoon.
Attentive or Not? Toward a Machine Learning Approach to Assessing Students’ Visible Engagement in Classroom Instruction
Authors: Goldberg Patricia , Sümer Ömer , Stürmer Kathleen , Wagner Wolfgang , Göllner Richard , Gerjets Peter , Kasneci Enkelejda , Trautwein Ulrich 
Published: December 2019

AbstractTeachers must be able to monitor students’ behavior and identify valid cues in order to draw conclusions about students’ actual engagement in learning activities. Teacher training can support (inexperienced) teachers in developing these skills by using videotaped teaching to highlight which indicators should be considered. However, this supposes that (a) valid indicators of students’ engagement in learning are known and (b) work with videos is designed as effectively as possible to reduce the effort involved in manual coding procedures and in examining videos. One avenue for addressing these issues is to utilize the technological advances made in recent years in fields such as machine learning to improve the analysis of classroom videos. Assessing students’ attention-related processes through visible indicators of (dis)engagement in learning might become more effective if automated analyses can be employed. Thus, in the present study, we validated a new manual rating approach and provided a proof of concept for a machine vision-based approach evaluated on pilot classroom recordings of three lessons with university students. The manual rating system was significantly correlated with self-reported cognitive engagement, involvement, and situational interest and predicted performance on a subsequent knowledge test. The machine vision-based approach, which was based on gaze, head pose, and facial expressions, provided good estimations of the manual ratings. Adding a synchrony feature to the automated analysis improved correlations with the manual ratings as well as the prediction of posttest variables. The discussion focuses on challenges and important next steps in bringing the automated analysis of engagement to the classroom.
Pathology-confirmed versus non pathology-confirmed cancer diagnoses: incidence, participant characteristics, and survival
Authors: van der Willik Kimberly D. , Rojas-Saunero Liliana P. , Labrecque Jeremy A. , Ikram M. Arfan , Schagen Sanne B. , Stricker Bruno H. , Ruiter Rikje 
Published: December 2019

AbstractCancer diagnoses which are not confirmed by pathology are often under-registered in cancer registries compared to pathology-confirmed diagnoses. It is unknown how many patients have a non pathology-confirmed cancer diagnosis, and whether their characteristics and survival differ from patients with a pathology-confirmed diagnosis. Participants from the prospective population-based Rotterdam Study were followed between 1989 and 2013 for the diagnosis of cancer. Cancer diagnoses were classified into pathology-confirmed versus non pathology-confirmed (i.e., based on imaging or tumour markers). We compared participant characteristics and the distribution of cancers at different sites. Furthermore, we investigated differences in overall survival using survival curves adjusted for age and sex. During a median (interquartile range) follow-up of 10.7 (6.3–15.9) years, 2698 out of 14,024 participants were diagnosed with cancer, of which 316 diagnoses (11.7%) were non pathology-confirmed. Participants with non pathology-confirmed diagnoses were older, more often women, and had a lower education. Most frequently non pathology-confirmed cancer sites included central nervous system (66.7%), hepato-pancreato-biliary (44.5%), and unknown primary origin (31.2%). Survival of participants with non pathology-confirmed diagnoses after 1 year was lower compared to survival of participants with pathology-confirmed diagnoses (32.6% vs. 63.4%; risk difference of 30.8% [95% CI 25.2%; 36.2%]). Pathological confirmation of cancer is related to participant characteristics and cancer site. Furthermore, participants with non pathology-confirmed diagnoses have worse survival than participants with pathology-confirmed diagnoses. Missing data on non pathology-confirmed diagnoses may result in underestimation of cancer incidence and in an overestimation of survival in cancer registries, and may introduce bias in aetiological research.
British Neolithic Axehead Distributions and Their Implications
Authors: Schauer Peter , Bevan Andrew , Shennan Stephen , Edinborough Kevan , Kerig Tim , Pearson Mike Parker 
Published: December 2019

AbstractNeolithic stone axeheads from Britain provide an unusually rich, well-provenanced set of evidence with which to consider patterns of prehistoric production and exchange. It is no surprise then that these objects have often been subject to spatial analysis in terms of the relationship between particular stone source areas and the distribution of axeheads made from those stones. At stake in such analysis are important interpretative issues to do with how we view the role of material value, supply, exchange, and demand in prehistoric societies. This paper returns to some of these well-established debates in the light of accumulating British Neolithic evidence andviathe greater analytical power and flexibility afforded by recent computational methods. Our analyses make a case that spatial distributions of prehistoric axeheads cannot be explained merely as the result of uneven resource availability in the landscape, but instead reflect the active favouring of particular sources over known alternatives. Above and beyond these patterns, we also demonstrate that more populated parts of Early Neolithic Britain were an increased pull factor affecting the longer-range distribution of these objects.
State of the art: leadless ventricular pacing
Authors: Steinwender C. , Lercher P. , Schukro C. , Blessberger H. , Prenner G. , Andreas M. , Kraus J. , Ammer M. , Stühlinger M. 
Published: December 2019

Abstract
Background
Cardiac pacing has been shown to improve quality of life and prognosis of patients with bradycardia for almost 60 years. The latest innovation in pacemaker therapy was miniaturization of generators to allow leadless pacing directly in the right ventricle. There is a long history and extensive experience of leadless ventricular pacing in Austria. However, no recommendations of national or international societies for indications and implantation of leadless opposed to transvenous pacing systems have been published so far.

Results
A national expert panel of skilled implanters gives an overview on the two utilized leadless cardiac pacing systems and highlights clinical advantages as well as current knowledge of performance and complication rates of leadless pacing. Furthermore, a national consensus for Austria is presented, based on recent studies and current know-how, specifically including indications for leadless pacing, management of infection, suggestions for qualification, and training of the operators and technical standards.

Conclusions
Leadless pacing systems can be implanted successfully with a low complication rate, if suggestions for indications and technical requirements are followed.

Condensed abstract
An overview of the two utilized leadless cardiac pacing systems is given, specifically highlighting clinical advantages as well as current knowledge of performance and complication rates. Furthermore, a national consensus for Austria is presented, specifically including indications for leadless pacing, management of infection, and suggestions for qualification and technical standards.
Time/sequence-dependent scheduling: the design and evaluation of a general purpose tabu-based adaptive large neighbourhood search algorithm
Authors: He Lei , de Weerdt Mathijs , Yorke-Smith Neil 
Published: December 2019

AbstractIn intelligent manufacturing, it is important to schedule orders from customers efficiently. Make-to-order companies may have to reject or postpone orders when the production capacity does not meet the demand. Many such real-world scheduling problems are characterised by processing times being dependent on the start time (time dependency) or on the preceding orders (sequence dependency), and typically have an earliest and latest possible start time. We introduce and analyze four algorithmic ideas for this class of time/sequence-dependent over-subscribed scheduling problems with time windows: a novel hybridization of adaptive large neighbourhood search (ALNS) and tabu search (TS), a new randomization strategy for neighbourhood operators, a partial sequence dominance heuristic, and a fast insertion strategy. Through factor analysis, we demonstrate the performance of these new algorithmic features on problem domains with varying properties. Evaluation of the resulting general purpose algorithm on three domains—an order acceptance and scheduling problem, a real-world multi-orbit agile Earth observation satellite scheduling problem, and a time-dependent orienteering problem with time windows—shows that our hybrid algorithm robustly outperforms general algorithms including a mixed integer programming method, a constraint programming method, recent state-of-the-art problem-dependent meta-heuristic methods, and a two-stage hybridization of ALNS and TS.
On Photographing Artists’ Books
Authors: Čiricaitė Egidija 
Published: December 2019

AbstractArtists’ books are challenging to photograph. They function as a unit of tightly conceptually-bound visual, textual and material elements in addition to a heightened self-awareness of the work's booksness. Binding, size, weight, and shape of the book, translucency, texture, thickness of paper, placement of images and/or text on the page or off the page interact with other graphic elements; they control, and direct the reader towards the expressive components of meaning which arise from pace, haptic experience, and visual or structural stylistic choices. Most of such information gets sacrificed in the process of documentation. Here I discuss some of such issues of photographing artists books for this journal and my solutions to replicating each artists’ book within the physical and thematic constraints of this publication: I tried not only to visualize the books’ content but also to translate some of the experience of how that content makes itself meaningful to the reader.
Testing the ‘Fear of Floating’ Hypothesis: A Statistical Analysis for Eight African Countries
Authors: Ahmad Ahmad Hassan , Pentecost Eric J. 
Published: December 2019

AbstractThis paper revisits the fear of floating hypotheses for eight African countries from the collapse of the Bretton Woods fixed exchange rate system in the early 1970s up until December 2017. This long period of calendar time allows us to extend previous studies by examining the fear of floating hypotheses in two distinct ways. First, we look at a set of descriptive statistics to compare the degree of exchange rate flexibility under alternative de jure exchange rate regimes. We find no statistical difference between exchange volatility between declared floaters and fixers, but greater reserve volatility between the floaters, which is suggestive of fear of floating. Second, we use a non-linear, threshold VAR model, estimated for each country, to test for a relationship between exchange rate changes and reserve changes. The results suggest some evidence of a fear of floating for countries which have declared a de jure floating regime, with the regime-dependent impulse responses indicating that exchange rate appreciation due to positive reserve shocks is more prevalent in the high reserve regimes, indicative that level of foreign reserves available are important for their exchange rate policies. In general, although the countries with de jure floating regimes have a lower threshold than those with pegged regimes, reserves adjust by more than the exchange rates showing a fear of floating.
Realism, perspectivism, and disagreement in science
Authors: Massimi Michela 
Published: December 2019

AbstractThis paper attends to two main tasks. First, I introduce the notion of perspectival disagreement in science. Second, I relate perspectival disagreement in science to the broader issue of realism about science: how to maintain realist ontological commitments in the face of perspectival disagreement among scientists? I argue that often enough perspectival disagreement is not at the level of the scientific knowledge claims but rather of the methodological and justificatory principles. I introduce and clarify the notion of ‘agreeing-whilst-perspectivally-disagreeing’ with an episode from the history of modern physics: namely, how we came to agree about the electric charge as a minimal natural unit despite different scientific perspectives and associated data-to-phenomena inferences available for it in the period 1897–1906.
“A Cancer in the Minds of Youth?” A Qualitative Study of Problematic Smartphone Use among Undergraduate Students
Authors: Yang Zeyang , Asbury Kathryn , Griffiths Mark D. 
Published: December 2019

AbstractThere is empirical evidence to suggest that problematic smartphone use (PSU) is associated with mental health problems including anxiety in educational settings. This qualitative study explored attitudes towards—and self-reported impacts of—smartphone use among British young adult students, as well as perceived causes of PSU. Free-response written accounts were gathered from 265 British undergraduates at an English university. Open-ended questions were asked about their attitudes towards smartphone use, their reasons for using their smartphones, and what they perceived as the consequences of their smartphone use. Narratives were analyzed using framework analysis and a thematic framework was identified. The three main consequences of PSU described by participants were (1) uncontrolled frequent checking of smartphones, (2) using smartphones late at night, and irrelevant use of smartphones in class. The main reported explanations for PSU were fear of missing messages, boredom in class, poor self-regulation, and external reasons (e.g., boring lectures). Smartphone use was reported to have both positive and negative impacts on young adults’ life satisfaction, social relationships, physical health, and study. Many participants reported that they need to develop better self-regulation to address their PSU. Findings suggest that smartphone use can have benefits as well as potentially causing harm among university students. PSU can—in some cases—be understood as reflecting mental well-being issues, poor self-regulation, and social problems.
Bariatric Surgery in Cirrhotic Patients: Is It Safe?
Authors: Younus Hafsa , Sharma Amit , Miquel Rosa , Quaglia Alberto , Kanchustambam Subba Rao , Carswell Kirstin A , Patel Ameet G. 
Published: December 2019

Abstract
Introduction
Ten percent of cirrhotic patients are known to have a high risk of postoperative complications. Ninety percent of bariatric patients suffer from non-alcoholic fatty liver disease (NAFLD), and 50% of them may develop non-alcoholic steatohepatitis (NASH) which can progress to cirrhosis. The aim of this study was to assess whether the presence of cirrhosis at the time of bariatric surgery is associated with an increased rate and severity of short- and long-term cirrhotic complications.

Methods
A cohort of 110 bariatric patients, between May 2003 and February 2018, who had undergone liver biopsy at the time of bariatric surgery were reassessed for histological outcome and divided into two groups based on the presence (C, n = 26) or absence (NC, n = 84) of cirrhosis. The NC group consisted of NASH (n = 49), NAFLD (n = 24) and non-NAFLD (n = 11) liver histology. Medical notes were retrospectively assessed for patient characteristics, development of 30-day postoperative complications, severity of complications (Clavien-Dindo (CD) classification) and length of stay. The C group was further assessed for long-term cirrhosis-related outcomes.

Results
The C group was older (52 years vs 43 years) and had lower BMI (46 kg/m2 vs 52 kg/m2) and weight (126 kg vs 145 kg) compared to the NC group (p < 0.05). The C group had significantly higher overall complication rate (10/26 vs 14/84, p < 0.05) and severity of complications (CD class ≥ III, 12% vs 7%, p < 0.05) when compared to the NC group. The length of stay was similar between the two groups (5 days vs 4 days). The C group had significant improvement in model end-stage liver disease scores (7 vs 6, p < 0.01) with median follow-up of 4.5 years (range 2–11 years). There were no long-term cirrhosis-related complications or mortality in our studied cohort (0/26).

Conclusion
Bariatric surgery in cirrhotic patients has a higher risk of immediate postoperative complications. Long-term cirrhosis-related complications or mortality was not increased in this small cohort. Preoperative identification of liver cirrhosis may be useful for risk stratification, optimisation and informed consent. Bariatric surgery in well-compensated cirrhotic patients may be used as an aid to improve long-term outcome.
Parties, Civil Society, and the Deterrence of Democratic Defection
Authors: Bernhard Michael , Hicken Allen , Reenock Christopher , Lindberg Staffan I. 
Published: December 2019

AbstractThe third wave of democratization has given way to a reverse wave of autocratization. A critical question is what can be done to prevent democratic breakdowns and make democracy endure. A large body of historical-narrative and small-N comparative scholarship has suggested that an active mobilized civil society and institutionalized political parties can be mobilized to protect democracy from authoritarian takeovers. We provide the first rigorous set of empirical analyses to test this argument using data from the Varieties of Democracy (V-Dem) project for the period from 1900 to 2010. We find that both exert a robust, independent, and substantial effect on the survival of democracies. These findings have important policy implications for the international community.