bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digital mental health: locations and contexts in youths’ presentation of self in video consultations— a qualitative study
Authors: Gullslett Monika Knudsen , Larsen Frank , Nybakke Henriette Lauvhaug 
Published: December 2024

Abstract
Background
The long-established use of video consultation in mental health services has undergone significant historical development. This study reveals and discusses how video consultations influence youths’ presentation of self in video consultations and in different locations and contexts. This phenomenon will be examined in light of Goffman’s theory of frontstage and backstage in relation to the sense and impact of place, or placelessness, concidering mental health situations. The aim of this study was to explore whether and how therapy through a screen was experienced and to reveal challenges and opportunities that result from using digital tools to communicate in a therapeutic context. The study employed a hermeneutic-phenomenological approach to gain an understanding of youths' life-world experiences with video consultations in therapy. 33 qualitative interviews were performed with youths in the age between 16–23 years. The recruitment was carried out between mid-august 2021 and end of march 2022. All had participated in VC sessions with their therapist during the COVID-19 pandemic. The analysis followed an abductive approach, where iterative cycles between the empirical data and theoretical framework helped uncover both unexpected and novel insights into the youths' experiences with VC.

Results
The findings revealed two main themes to guide our investigation: 1) therapy through a screen versus F2F therapy and 2) different physical contexts for therapy through a screen. The findings show that youths’ experiences with the use of video consultations in therapy are diverse and heterogeneous.

Conclusions
Face-to-face communication may reduce ambiguity and uncertainty through the use of body language and eye contact. Face-to-face communication requires less cognitive effort to process and involves greater psychological distance than digital communication. The advantages of using video consultations include avoiding school days, avoiding long travel distances, connecting faster when needed, and having shorter conversations to catch up on challenges in collaboration. The implications of location and context may also impact youths’ presentation of self.
A simplified frequency-domain beamforming approach for active and passive surface wave surveys
Authors: Adari Sai Vivek , Naskar Tarun , Cox Brady R. 
Published: December 2024

Frequency-domain beamforming (FDBF) and cylindrical frequency-domain beamforming (CFDBF) techniques are among the most robust methods for extracting experimental phase velocity dispersion data from wavefields recorded during either active- or passive-source surface wave testing. FDBF and CFDBF transformations rely on calculating the spatiospectral correlation matrix to compute the steered power response spectrum, which is essential for extracting surface wave dispersion data. The dimensions of the spatiospectral correlation matrix are directly influenced by the frequency sampling and the number of sensors used in the survey setup. When the number of sensors is large, and/or the frequency range is broad, and/or the frequency sampling is dense, the spatiospectral correlation matrix size leads to a greater number of required computations to calculate the steered power response spectrum for the FDBF and CFDBF techniques. Therefore, we develop a simplified and computationally efficient FDBF algorithm for active and passive surface wave surveys. This method avoids the calculation of the spatiospectral correlation matrix and its multiplication with the Hermitian transpose of the steering vector, thereby reducing the computational complexity by an order of magnitude. Furthermore, by leveraging vectorization techniques, the developed algorithm uses matrix multiplications instead of loops, significantly heightening computational efficiency. We rigorously test the algorithm using surface wave data sets collected across diverse subsurface conditions with varying sensor arrays and acquisition parameters (e.g., sampling frequencies and window lengths) to evaluate its efficacy. The results demonstrate that our developed algorithm outperforms the conventional FDBF method in processing time, highlighting its practical effectiveness. This method shows promise for integration into surface wave data processing software, offering substantial improvements in computational efficiency without compromising accuracy.
Effectiveness of a Family-based Health Promotion Intervention for Women With Prior GDM: The Face-It RCT
Authors: Kragelund Nielsen Karoline , Dahl-Petersen Inger Katrine , Jensen Dorte Møller , Damm Peter , Ovesen Per , Mathiesen Elisabeth R , Kampmann Ulla , Vinter Christina Anne , Knorr Sine , Andersen Lise Lotte , Davidsen Emma , Jensen Nanna Husted , Aalders Jori , Thøgersen Maja , Timm Anne , Støvring Henrik , Maindal Helle Terkildsen 
Published: December 2024

Abstract

Context
Gestational diabetes mellitus (GDM) increases the risk of future type 2 diabetes (T2DM), but effective and feasible interventions to reduce this risk are lacking.

Objective
To evaluate the effectiveness of a family-based health promotion intervention on T2DM risk factors and quality of life among women with recent GDM.

Design
Multicenter, parallel, open-label randomized controlled trial with 2:1 allocation ratio.

Setting
Three sites in Denmark.

Participants
Women diagnosed with GDM.

Intervention(s)
The intervention consisted of (1) home visits with tailored family-based counseling (2) digital health coaching, and (3) structured cross-sectoral communication.

Main Outcome Measures
Primary outcomes were body mass index (BMI) and quality of life [12-Item Short-Form mental component score (SF12 MCS)] 1 year after delivery.

Results
We randomized 277 women to the intervention (n = 184) or usual care group (n = 93). The intervention did not result in significantly lower BMI [−0.44 kg/m2; 95% confidence interval (CI) −0.98 to 0.11] or higher SF12 MCS (0.06; 95% CI −2.15 to 2.27) compared to the usual care group. A prespecified post hoc analysis demonstrated a reduced BMI in the intervention group among women with BMI ≥25 kg/m2 (−0.86 kg/m2; 95% CI −1.58 to −0.14).
Analyses of secondary and tertiary outcomes indicated significantly lower 2-hour insulin (−94.3 pmmol/L; 95% CI −167.9 to −20.6) and triglycerides (−0.18 mmol/L; 95% CI −0.30 to −0.05) levels, and odds of fasting plasma glucose ≥6·1 mmol/L (odds ratio 0.33; 95% CI 0.12 to 0.91) in the intervention group.

Conclusion
The intervention did not result in lower BMI or increased quality of life but seemingly reduced other risk factors and lowered BMI in the subgroup of overweight women.
Prediction of Insulin Requirements by Explainable Machine Learning for Individuals With Type 1 Diabetes
Authors: Yoshimura Kai , Hirota Yushi , Saito Shuichiro , Nishikage Seiji , Yamamoto Akane , Takayoshi Tomofumi , Urai Shin , Ogawa Wataru 
Published: December 2024

Abstract

Context
Adverse events related to insulin therapy remain common in individuals with type 1 diabetes (T1D). Optimization of insulin dose can reduce the frequency of these events and help to prevent macrovascular and microvascular complications.

Objective
The aim of the present study was to develop machine-learning models to predict the total daily dose (TDD) of insulin on the basis of data available in routine clinical practice, to evaluate the performance of the models, and to interpret the relation between its predictions and features.

Methods
This retrospective observational study conducted at a single center recruited individuals diagnosed with T1D who visited Kobe University Hospital and used continuous glucose monitoring in combination with continuous subcutaneous insulin infusion between April 1, 2010 and February 29, 2024. We developed TDD prediction models based on machine learning and evaluated its performance on the basis of the mean absolute percentage error (MAPE). Explainable artificial intelligence frameworks were applied to the machine-learning model to facilitate interpretability.

Results
A total of 110 individuals with T1D were included in the study. The best-performing model, the random forest, achieved a MAPE of 19.8%. The most important feature of the model for prediction of the TDD of insulin was body weight, followed by waist circumference and carbohydrate intake.

Conclusion
We here developed machine-learning models that predict the TDD of insulin from clinical information. Such models could contribute to the treatment of many individuals undergoing insulin therapy, with further developments being warranted.
A Rare Case of Testosterone-Producing Non-Seminoma Germ-Cell Testicular Cancer
Authors: Mänd Sarah-Ålivia , Sjöholm Åke 
Published: December 2024

Abstract
Androgen secretion by testicular germ-cell tumors (GCTs) appears to be markedly rare and likely underreported in the literature. This case study highlights a patient with such a rare tumor, underscoring a notable and yet easily avoidable diagnostic oversight in one of the most prevalent cancers among men. We advocate for increased vigilance and the inclusion of specific symptomatic screening for hyperandrogenism of select patients in existing guidelines and, where appropriate, the implementation of standardized hormonal laboratory analyses in both pre- and post-orchidectomy assessments. These measures could enhance the reporting of cases, standardize care, and improve understanding of the underlying mechanisms of these rare tumors. Finally, future studies should explore the implications of androgen secretion for the prognosis and treatment of GCTs.
Impact of Female Sex and Mild Cortisol Secretion on Coagulation Profile in Adrenal Incidentalomas
Authors: Bonaventura Ilaria , Minnetti Marianna , Ferrari Davide , Hasenmajer Valeria , Tomaselli Alessandra , De Alcubierre Dario , Lenzi Andrea , Pofi Riccardo , Isidori Andrea M 
Published: December 2024

Abstract

Context
Studies describing the coagulation profile in adrenal adenomas still need to be added.

Objective
We explored how sex and mild autonomous cortisol secretion (MACS) affect coagulation parameters in patients with adrenal adenomas.

Design
Cross-sectional study.

Methods
From January 2019 until April 2023, participants in the Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations trial (NCT04127552) diagnosed with adrenal adenoma were categorised according to the 1 mg overnight dexamethasone-suppression test (1 mg-DST). Coagulation parameters were evaluated, and two-way ANOVA was used to elucidate the cortisol-by-sex interaction.

Results
Of 153 patients screened, 90 were enrolled (62.2% female, mean age 62 ± 10 years): 41 with non-functioning adrenal tumour (1 mg-DST ≤ 1.8 µg/dL), and 49 with a MACS (1 mg-DST &gt; 1.8 µg/dL). Platelet counts were higher in the MACS group (P = .01). Regression analysis identified female sex (B = 36.603, P = .011), 1mg-DST (B = 0.238, P = .042), and younger age (B = −1.452, P = .038) as independent predictors for elevated platelet count. In patients with MACS, women exhibited higher levels of procoagulant factors fibrinogen (P = .004) and factor VIII (P &lt; .001), and coagulation inhibitors protein C (P = .003) and antithrombin III (P = .005) than males. No differences were observed in the non-functioning adrenal tumour group, providing a cortisol-by-sex interaction regarding fibrinogen (P = .047), factor VIII (P = .046), and protein C (P = .028).

Conclusion
Our findings revealed a worse coagulation profile in women with MACS, underscoring the need for a sex-specific approach in clinical practice to manage thrombotic risks effectively. Dedicated prospective studies are needed to validate and integrate these findings into clinical strategies for thromboprophylaxis.
Cajal body formation is regulated by coilin SUMOylation
Authors: Tucker Sara K. , McLaurin Douglas M. , Hebert Michael D. 
Published: December 2024

ABSTRACT
Cajal bodies (CBs) are membraneless organelles whose mechanism of formation is still not fully understood. Many proteins contribute to the formation of CBs, including Nopp140 (NOLC1), WRAP53 and coilin. Coilin is modified on multiple different lysine residues by SUMO, the small ubiquitin-like modifier. In addition to its accumulation in CBs, coilin is also found in the nucleoplasm, where its role is still being evaluated. Here, we demonstrate a novel mechanism of CB regulation by examining the interaction changes of coilin when its SUMOylation is disrupted. The impact of global SUMOylation inhibition and targeted disruption of coilin SUMOylation on CB formation was examined. We found that two types of global SUMOylation inhibition and expression of SUMO-deficient coilin mutants increased CB number but decreased CB size. Additionally, we saw via coimmunoprecipitation that a SUMO-deficient coilin mutant has altered interaction with Nopp140. This demonstrates increased mechanistic ties between CB formation and SUMOylation.
Conhecimento dos profissionais que atuam no processo de dispensação por dose unitária
Authors: Trassante Jéssica , Flores Cecilia Dias , Mastella Mauro 
Published: December 2024

Hospitais devem fornecer cuidados de qualidade, priorizando a segurança do paciente e a qualificação dos profissionais para garantir a excelência dos serviços prestados. O evento adverso é uma ocorrência imprevista, indesejável ou potencialmente perigosa na instituição de saúde. Estima-se que cerca de 8.000 mortes anuais ocorram devido a erros de medicação, e muitas delas poderiam ser evitadas. O processo de distribuição de medicamentos por dose unitária contribui significamente na redução desses erros. As instituições devem buscar conhecer as fragilidades do seu processo, a fim de buscar por estratégias qualificando o serviço. Esta pesquisa analisou o conhecimento dos profissionais sobre o processo de dispensação dos medicamentos de dose unitária para entender as potencialidades e fragilidades deste processo, identificando as carências existentes sobre ele e assim encontrar estratégias para diminuição dos eventos adversos. O estudo foi conduzido de forma transversal, abordando aspectos qualitativos e quantitativos. Participaram 42 profissionais diretamente envolvidos no processo, onde a coleta de dados incluiu observação participante e questionários com perguntas abertas e fechadas. Os profissionais encontram algumas fragilidades em entender o seu papel no processo e compreendê-lo como um todo. Como aspectos positivos pontuados estão: otimização do tempo de assistência, redução de desperdícios de institucionais e diminuição de erros de administração dos medicamentos. A implementação do questionário foi profícua, pois os colaboradores expuseram suas percepções sobre o processo, sendo que a partir dessas percepções, a instituição pode criar uma qualificação específica para esses profissionais, com base nas fragilidades e oportunidades de melhoria encontradas.
A utilidade do Índice de Barthel na avaliação e monitoramento da recuperação pós-AVC na fase aguda
Authors: Karsten Luciana Ferreira , Safanelli Juliana Antunes , Rosa Flávia Souza da , Marcante Jessica de Souza , Baratto Filho Flares , Soares Antonio Vinicius 
Published: December 2024

O Acidente Vascular Cerebral (AVC) é uma condição clínica com diversas repercussões para o indivíduo. Para auxiliar a equipe de saúde, emprega-se inúmeras escalas específicas para avaliar desde a gravidade do AVC, a funcionalidade e a capacidade motora pós-evento. Nesse contexto, este estudo objetivou verificar se o Índice de Barthel foi eficaz ao ser utilizado como ferramenta de avaliação e monitoramento da recuperação de pacientes com AVC em fase aguda, destacando sua utilidade no acompanhamento da reabilitação. Para tanto, utilizou-se uma abordagem quantitativa e retrospectiva. A amostra foi composta de 1199 pacientes. Os dados foram analisados com o software GraphPad Prism 8®. Utilizada estatística descritiva (média ou mediana, desvio padrão ou intervalo interquartil, e ainda, distribuição de frequência). O teste de Shapiro-Wilk foi usado para verificação da normalidade dos dados. Os Testes t e Wilcoxon foram usados para comparar os subgrupos de homens e mulheres quanto às variáveis paramétricas e não paramétricas, respectivamente. Para avaliar as relações entre as variáveis controladas foi utilizada uma matriz de correlação (Teste de Spearman). Foi adotado um nível de significância de 5% (p<0,05) para todos os testes estatísticos. Conclui-se com a análise de correlação de Spearman, que o Índice de Barthel, juntamente com a Escala de Rankin e NHISS (correlações moderadas à forte), pode ser uma boa ferramenta para acompanhamento da recuperação dos pacientes com AVC na fase aguda. Esta produção deriva da pesquisa de doutorado em Saúde e Meio Ambiente “Implantação de uma rede de atendimento interdisciplinar de reabilitação pós-acidente vascular cerebral na cidade de Joinville, SC ”, em desenvolvimento no Programa de Pós-graduação em Saúde e Meio Ambiente, na Universidade da Região de Joinville (UNIVLLE), sob orientação do Prof. Dr. Flares Baratto Filho e coorientação do Prof. Dr. Antonio Vinicius Soares e apoio financeiro (Bolsa) da Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina, FAPESC, Brasil.
Microwave-resonator-enabled broadband on-chip electro-optic frequency comb generation
Authors: Chen Zhaoxi , Zhang Yiwen , Feng Hanke , Zeng Yuansong , Zhang Ke , Wang Cheng 
Published: December 2024

Optical frequency combs play a crucial role in optical communications, time-frequency metrology, precise ranging, and sensing. Among various generation schemes, resonant electro-optic combs are particularly attractive for their excellent stability, flexibility, and broad bandwidths. In this approach, an optical pump undergoes multiple electro-optic modulation processes in a high-Q optical resonator, resulting in cascaded spectral sidebands. However, most resonant electro-optic combs to date make use of lumped-capacitor electrodes with relatively inefficient utilization of the input electrical power. This design also reflects most electrical power back to the driving circuits and necessitates costly radio-frequency (RF) isolators in between, presenting substantial challenges in practical applications. To address these issues, we present an RF circuit friendly electro-optic frequency comb generator incorporated with on-chip coplanar microwave resonator electrodes, based on a thin-film lithium niobate platform. Our design achieves more than three times electrical power reduction with minimal reflection at the designed comb repetition rate of ∼25  GHz. We experimentally demonstrate broadband electro-optic frequency comb generation with a comb span of >85  nm at a moderate electrical driving power of 740 mW (28.7 dBm). Our power-efficient and isolator-free electro-optic comb source could offer a compact, low-cost, and simple-to-design solution for applications in spectroscopy, high-precise metrology, and optical communications.
Un passo di Michele di Efeso e l’origine del commento composito all’Etica Nicomachea
Authors: Natali Carlo 
Published: December 2024

Abstract
A passage from Michael of Ephesus’ Commentary on the Nicomachean Ethics, book V (p. 50, 6–10 Hayduck), gives some information on the Anonymous Commentary on the Nicomachean Ethics, books II–IV. Michael cites a series of ancient annotations to the third book, written by ancient exegetes and which have come down to him. It can therefore be assumed that Michael had the Anonymous Commentary in front of him when he wrote these lines. It is thus possible to assume that it was Michael of Ephesus himself who organised the entire commentary on the Nicomachean Ethics and inserted the Anonymous Commentary on Books II-IV after Eustratius’ commentary on Book I and before his own commentary on Book V.
Dynamic characteristics tests of full-scale lead rubber bearing (LRB)
Authors: Mori Kentaro , Nagashima Gentaro , Mori Takahiro , Muramatsu Akitsugu , Ogata Takanori 
Published: December 2024

Abstract
Several types of dynamic tests were performed using a full-scale lead rubber bearing (LRB) that has a lead plug embedded at the center of laminated natural rubber. The horizontal and vertical characteristics of the LRB due to various shear strains, frequencies, cyclic effect and compressive stresses were obtained by the experiments. It was confirmed that the variations of the obtained horizontal and vertical characteristics satisfied allowable variations defined in European standard for Anti-seismic devices (EN15129-2009).
Moin Moin is schon Gesabbel: constructing Northern German identity in commercial Instagram posts
Authors: Schram Frederike 
Published: December 2024

Abstract
This paper shows how commercial Instagrammers construct a shared Northern German identity by employing the regional language Low German and other (visual) means. In today’s mobile and globalised societies, the use and functions of regional or minority languages are changing. Besides communicative purposes and the construction of regional identities in multilingual societies, these languages are commodified as signs of authenticity and regionality. Challenged by High German and other dominant languages, Low German is still spoken in the domestic domain and by older generations. It has recently gained significance in marketing and as a marker of regional identity. The question of how commercial Instagrammers construct regional identity is answered using a multimodal corpus of 1,157 Instagram posts and a discourse analysis based, qualitative and quantitative data analysis. The findings suggest that the Instagrammers express regional identity through three strategies: 1) Using well-known Low German words and short texts; 2) portraying character traits and humour as key features of Northern Germanness, and 3) a clear distinction between an out-group and an in-group through meta-linguistic commentary. Together, these strategies construct a collective, generalised regional identity, reinforcing the Instagrammers’ “Northern Germanness” and allowing consumers to express their regional identities through this content and products.
Rap Devil versus Rap God: impoliteness in a rap battle
Authors: Oğuz Enis , Işık-Güler Hale 
Published: December 2024

Abstract
Using a line-by-line analysis of the key conversational instances identified in an asynchronous rap battle between Eminem (in Killshot) and Machine Gun Kelly (in Rap Devil), this study investigates diss tracks as manifestations of impoliteness. As a framework for our analysis, we adopt an overlay of Spencer-Oatey’s rapport management model/principles and Culpeper’s framework of impoliteness strategies/formulae. The results show that both rappers tried to out-diss each other by verbalizing a multitude of insults, curses, dismissals, and more. The paper builds on the relationship between power and impoliteness, the concept of authenticity in rap, prescribed and proscribed language use in hip-hop culture, and displays of identity roles of the rappers. The findings and discussion offer novel contributions to impoliteness research, as the current study is the first to investigate impoliteness in an asynchronous rap battle between two White rappers. In light of the analyses, we define diss track exchanges as asynchronous rap battles characterized by the abundant use of coercive impoliteness for entertainment.