bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does attachment style moderate the effect of computer‐mediated versus face‐to‐face conflict discussions?
Authors: Pollmann Monique M. H. , Crockett Erin E. , Vanden Abeele Mariek M. P. , Schouten Alexander P. 
Published: November 2020

AbstractSuccessful conflict resolution is important in romantic relationships. With the advent of computer‐mediated communication (CMC), partners can resolve conflict using CMC. But is CMC as effective as face‐to‐face communication for conflict resolution? And does the effectiveness depend on attachment style? We asked 100 romantic couples to discuss a conflict topic and randomly assigned them to do so face‐to‐face or via CMC. Levels of distress, anger, and conflict resolution did not differ between face‐to‐face and CMC discussions. Attachment style did not moderate these findings. A more anxious and a more avoidant attachment style were associated with higher levels of distress and anger. We conclude that there is no indication that resolving conflict face‐to‐face has advantages over resolving conflict via CMC.
Characterization of canine epidermal organoid cultures by immunohistochemical analysis and quantitative PCR
Authors: Wiener Dominique J. , Studer Isabelle C. , Brunner Magdalena A.T. , Hermann Andreas , Vincenti Simona , Zhang Meng , Groch Kátia R. , Welle Monika M. 
Published: November 2020

BackgroundKeratinocyte organoids can be used as a tool to evaluate epidermal structure, function and dysfunction.ObjectivesTo optimize the canine keratinocyte organoid system and produce organoids that are structurally equivalent to in vivo canine epidermis, in order to enable studies that focus on epidermal diseases and diseases resulting from an impaired epidermal barrier.AnimalsSkin biopsies were obtained from five recently euthanized dogs of different breeds with no skin abnormalities.Methods and materialsCells derived from microdissected interfollicular epidermis were seeded in basement membrane extract and epidermal organoids were grown under different media conditions. Organoids were characterized to assess cell morphology and architecture in haematoxylin and eosin‐stained slides and expression of selected epidermal markers (keratin 5, keratin 10, loricrin and filaggrin) by immunohistochemical analysis and quantitative reverse transcription PCR.ResultsThe selected epidermal markers were expressed in the same epidermal layers in the organoids cultured in expansion medium and differentiation medium as in normal interfollicular epidermis, yet restriction to the distinct layers was best achieved with expansion medium. Comparison of the mRNA expression levels of these markers revealed that relative expression is similar in organoids cultured in expansion medium and normal canine epidermis, while it differs in organoids cultured in differentiation medium.Conclusion and clinical importanceOrganoids cultured in expansion medium have an equivalent structure to the interfollicular epidermis and express key marker proteins in similar proportions. Epidermal organoids are therefore a promising in vitro model to study epidermal structure, function and dysfunction.
Numerical and Experimental Studies of Ballistic Compression Process in a Soft Recovery System
Authors: Mathur Girijesh , Tiwari Nachiketa , Chaturvedi Neha 
Published: November 2020

Abstract
A ballistic compression type soft recovery system can stop a free-flying supersonic projectile in a controlled manner. The moment such a projectile enters the System, a normal shock gets created and starts hurtling down, to kick off a train of events involving shock reflections, diaphragm rupture, shock merger, creation of new shocks and contact discontinuities, and expansion wave-shock interactions. A good understanding of these phenomena and sensitivity of the System's performance to changes in design parameters is needed to design an efficient soft recovery system. Unfortunately, not much information is available about this. The present work fills this gap. We have developed a numerical model for the system and conducted sensitivity analyses using four design parameters; pressure, molecular weight, the ratio of specific heats, and temperature of gas used in the system. We show that while there is a strong, positive correlation between the first two parameters and projectile deceleration, the other two parameters are less critical. We conducted experiments to corroborate our conclusions and improve our numerical model. Post such improvements, we found the difference between simulation and experimental data to be acceptable. Experiments also confirmed the findings of our sensitivity studies. Finally, we conducted a two-dimensional finite volume analysis to understand the reasons underlying the residual difference between our numerical and experimental data. We show that such differences are due to pressure-rise at a point once a shock passes by it, and such a rise in pressure is attributable to boundary layer effects.
Radiological Risk Assessment of Radon Gas in Bricks Samples in Iraq
Authors: Abojassim Ali Abid 
Published: November 2020

AbstractNaturally occurring radioactive radon gas is produced from radioactive decay of naturally radioactive element radium and emits alpha particles. The radon gas is the main source of natural background radiation that contributes to about more than 60% of the annual radiation dose to humans on Earth. In this research, radon concentrations (222Rn) in brick samples that are available in Iraqi markets were measured using solid state nuclear track (CR-39). Also, uranium-238 (238U), radium-226 (226Ra) were calculated in all samples under study together with some radiation parameters such as exhalation of radon gas rate (FO), annual effective dose (DRn), and excess lifetime cancer risk (ELCR). It was found that, the average value of 222Rn, 238U, and 226Ra concentrations in studied samples were 48.75 ± 10.61 Bq/m3, 0.084 ± 0.02 ppm, and 115.57 ± 29.60 mBq/kg, respectively. Also, it was found that the average of each of FO, DRn, and ELCR were 27.54 ± 5.99 μBq/m2.h, 0.88 ± 0.17 nSv/y, and (3.01 ± 0.65)×10−3, respectively. After data analysis, the resulted data were examined and compared with the global average and the permissible limits which recommended by the international scientific agencies such as International Commission on Radiological Protection (ICRP 2010), United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR 2017), Organization for Economic Cooperation and Development (OECD 2009). It was found that radiation levels from brick samples used in local markets for most models fell within the permissible limits and may not cause any danger to human beings.
Assessment of Turbulence Models for Low Reynolds Number Flows and Their Computational Costs, Part 1: Staggered Tube Bank
Authors: Mancuso Thomas , Mukherjee Abhijit 
Published: November 2020

Abstract
This study investigates the accuracy of computational fluid dynamics (CFD) models to predict heat transfer in turbulent separated flows at low Reynolds numbers. This article will focus on flow in a staggered tube bank, while its companion articular will focus on a square prism (cylinder) in cross flow. Experimental data for both local heat transfer and velocity profiles are available for these cases and have been used extensively in the literature to evaluate various CFD methods. Six unsteady models were used and the results show that the unsteady shear stress transport (SST) model provided good overall accuracy relative to the mean Nusselt number for both cases. However, the SST model failed to accurately predict local variations. The partially averaged Navier–Stokes (PANS) variant of the SST model did show a marked improvement over the baseline SST model. The dynamic Smagorinsky large eddy simulation (LES) showed a much-improved fidelity to the local Nusselt number but unpredicted the actual values. The computational cost for the LES model was significant and it was found that the computationally expensive models with higher degrees of resolved turbulence did not necessarily return better results. Finally, the pressure drop results for the six models were scaled to predict the mean Nusselt number with the generalized Leveque method and were found to be very accurate. This method should prove useful to predict heat transfer performance with computationally less expensive cold flow results.
Study of potentially preventable hospitalisations (PPH) for chronic conditions: what proportion are preventable and what factors are associated with preventable PPH?
Authors: Johnston Jennifer , Longman Jo , Ewald Dan , King Jonathan , Das Sumon , Passey Megan 
Published: November 2020

IntroductionThe proportion of potentially preventable hospitalisations (PPH) which are actually preventable is unknown, and little is understood about the factors associated with individual preventable PPH. The Diagnosing Potentially Preventable Hospitalisations (DaPPHne) Study aimed to determine the proportion of PPH for chronic conditions which are preventable and identify factors associated with chronic PPH classified as preventable.SettingThree hospitals in NSW, Australia.ParticipantsCommunity-dwelling patients with unplanned hospital admissions between November 2014 and June 2017 for congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), diabetes complications or angina pectoris. Data were collected from patients, their general practitioners (GPs) and hospital records.Outcome measuresAssessments of the preventability of each admission by an Expert Panel.Results323 admissions were assessed for preventability: 46% (148/323) were assessed as preventable, 30% (98/323) as not preventable and 24% (77/323) as unclassifiable. Statistically significant differences in proportions preventable were found between the three study sites (29%; 47%; 58%; p≤0.001) and by primary discharge diagnosis (p≤0.001).Significant predictors of an admission being classified as preventable were: study site; final principal diagnosis of CHF; fewer diagnoses on discharge; shorter hospital stay; GP diagnosis of COPD; GP consultation in the last 12 months; not having had a doctor help make the decision to go to hospital; not arriving by ambulance; patient living alone; having someone help with medications and requiring help with daily tasks.ConclusionsThat less than half the chronic PPH were assessed as preventable, and the range of factors associated with preventability, including site and discharge diagnosis, are important considerations in the validity of PPH as an indicator. Opportunities for interventions to reduce chronic PPH include targeting patients with CHF and COPD, and the provision of social welfare and support services for patients living alone and those requiring help with daily tasks and medication management.
Only eye study 2 (OnES 2): ‘Am I going to be able to see when the patch comes off?’ A qualitative study of patient experiences of undergoing high-stakes only eye surgery
Authors: Jones Lee , Taylor Deanna J , Sii Freda , Masood Imran , Crabb David P , Shah Peter 
Published: November 2020

ObjectivesOcular surgery is a source of significant concern for many patients, especially in high-stakes circumstances. The purpose of this study was to explore patient experiences of undergoing surgery on their only-seeing eye.DesignA qualitative investigation using semistructured face-to-face interviews. Transcripts were analysed using thematic analysis.SettingHospital eye service in the UK.ParticipantsTwelve participants with a diagnosis of glaucoma with worse eye visual acuity <3/60± end-stage visual field loss. All participants had experience of undergoing surgery on their better-seeing (ie, ‘only’) eye.ResultsData were coded into three key themes relating to (1) emotional impact of surgery, (2) burden of visual loss and (3) coping with surgery. Patients reported depressive symptoms at all stages of their surgical journey; concern about poor visual outcomes was a common feature. Only eye surgery imposes an emotional burden due to the uncertainty regarding individuals’ ability to continue daily activities and maintaining social roles. Burden extended to the inconvenience of frequent hospital visits and difficulties with follow-up care. Participants’ ability to cope effectively with surgery appeared to be linked to extent of support from healthcare professionals. Key areas in developing trust and support were an open and transparent dialogue between surgeons and patients, continuity of care, patient inclusion in decision-making, and observable empathy.ConclusionsThe findings indicate a need for an enhanced model of care in only eye surgery to better target patient preferences and allay concerns inherent with these procedures.
Abstract 116: Impella Device Success: Walking Home After Cardiogenic Shock From Ventricular Fibrillation
Authors: Smith Christopher , Menon Vivek , Smith Dantwan 
Published: November 2020

Ventricular fibrillation is a fatal arrhythmia due to its detrimental impact on cardiac output. Managing patients in V-Fib arrest is often challenging, but newer mechanical support devices such as Impella CP 5.0 (Abiomed, Danvers, MD) are proving to be an excellent adjunct to inotrope and vasopressor therapy.
We present a 75-year-old female with a medical history of atrial fibrillation and obstructive sleep apnea that presented to the ER unresponsive. On arrival, the patient was pulseless and initial rhythm on telemetry revealed ventricular fibrillation. The patient demonstrated minimally reactive pupils to light, negative corneal reflex, and lower extremity clonus.
ROSC was achieved with electric defibrillation and two rounds of CPR. Chest radiograph revealed mild bilateral pulmonary congestion. Head CT revealed no acute intracranial pathology. The patient was placed on targeted temperature management protocol for the next 48 hours. Emergent left heart catheterization revealed no signs of occlusive coronary disease. TTE revealed left ventricular ejection fraction 5-10%, likely from stunned myocardium.
The patient continued to clinically decline and decision was made to place an Impella device for further hemodynamic support. Unlike ECMO, the Impella fully unloaded the LV and allowed diastolic coronary filling. The patient ultimately demonstrated significant improvement and repeat TTE revealed an improved EF of 45-50%.
Prior to hospital discharge, an AICD was placed for primary SCD prevention. The patient maintained close outpatient follow-up with her cardiologist and PCP. This case illustrates the importance life-saving mechanical support devices such as Impella in the setting of cardiogenic shock, even from non-ischemic ventricular fibrillation.
Modulation of the Occurrence of Heatwaves over the Euro-Mediterranean Region by the Intensity of the Atlantic Multidecadal Variability
Authors: Qasmi Saïd , Sanchez-Gomez Emilia , Ruprich-Robert Yohan , Boé Julien , Cassou Christophe 
Published: November 2020

AbstractThe influence of the Atlantic multidecadal variability (AMV) and its amplitude on the Euro-Mediterranean summer climate is studied in two climate models, namely CNRM-CM5 and EC-Earth3P. Large ensembles of idealized experiments have been conducted in which North Atlantic sea surface temperatures are relaxed toward different amplitudes of the observed AMV anomalies. In agreement with observations, during a positive phase of the AMV both models simulate an increase (decrease) in temperature of 0.2°–0.8°C and a decrease (increase) in precipitation over the Mediterranean basin of 0.1–0.2 mm day−1 (northern half of Europe) compared to a negative phase. Heatwave durations over the Mediterranean land regions are 40% (up to 85% over the eastern regions) longer for a moderate amplitude of the AMV. Lower and higher amplitudes lead to longer durations of ~30% and ~100%, respectively. A comparison with observed heatwaves indicates that the AMV can considerably modulate the current anthropogenically forced response on heatwaves durations depending on the area and on the AMV amplitude. The related anticyclonic anomalies over the Mediterranean basin are associated with drier soils and a reduction of cloud cover, which concomitantly induce a decrease (increase) of the latent (sensible) heat flux, and an enhancement of the downward radiative fluxes over lands. It is found that both tropical and extratropical forcings from the AMV are needed to trigger mechanisms, which modulate the atmospheric circulation over the Euro-Atlantic region. The amplitude of the local climate response over the Mediterranean basin evolves linearly with the amplitude of the AMV. However, the strength of this relationship differs between the models, and depends on their intrinsic biases.
The Role of an Indian Ocean Heating Dipole in the ENSO Teleconnection to the North Atlantic European Region in Early Winter during the Twentieth Century in Reanalysis and CMIP5 Simulations
Authors: Joshi Manish K. , Abid Muhammad Adnan , Kucharski Fred 
Published: November 2020

AbstractIn this study the role of an Indian Ocean heating dipole anomaly in the transition of the North Atlantic–European (NAE) circulation response to El Niño–Southern Oscillation (ENSO) from early to late winter is analyzed using a twentieth-century reanalysis and simulations from phase 5 of the Coupled Model Intercomparison Project (CMIP5). It is shown that in early winter a warm (cold) ENSO event is connected through an atmospheric bridge with positive (negative) rainfall anomalies in the western Indian Ocean and negative (positive) anomalies in the eastern Indian Ocean. The early winter heating dipole, forced by a warm (cold) ENSO event, can set up a wave train emanating from the subtropical South Asian jet region that reaches the North Atlantic and leads to a response that spatially projects onto the positive (negative) phase of the North Atlantic Oscillation. The Indian Ocean heating dipole is partly forced as an atmospheric teleconnection by ENSO, but can also exist independently and is not strongly related to local Indian Ocean sea surface temperature (SST) forcing. The Indian Ocean heating dipole response to ENSO is much weaker in late winter (i.e., February and March) and not able to force significant signals in the North Atlantic region. CMIP5 multimodel ensemble reproduces the early winter Indian Ocean heating dipole response to ENSO and its transition in the North Atlantic region to some extent, but with weaker amplitude. Generally, models that have a strong early winter ENSO response in the subtropical South Asian jet region along with tropical Indian Ocean heating dipole also reproduce the North Atlantic response.
Development and Analysis of a Closed-Chain Wheel-Leg Mobile Platform
Authors: Wei Chaoran , Yao Yanan , Wu Jianxu , Liu Ran 
Published: November 2020

Abstract
Current research concerning legged platforms and wheeled platforms primarily focuses on terrain adaptive capability and speed capability, respectively. Compared with wheeled platforms, legged platforms with a closed-chain mechanism still present deficiencies regarding speed ability. To integrate the advantages of these two types of platforms, a wheel-leg mobile platform with two modes based on a closed-chain mechanism is proposed. First, a closed-chain mechanism that generates a high-knee trajectory in legged mode is designed and analyzed based on kinematic analysis. To improve the platform’s obstacle-surmounting performance, the dimensional parameters of the closed-chain mechanism are optimized and the design requirements for the platform’s frame are analyzed. In addition, the particular structure of the leg group is designed to realize transformation between legged mode and wheeled mode. The mobility of the constructed platform is calculated through an obstacle-surmounting probability analysis. The performances of the two motion modes are analyzed and compared by conducting dynamic simulations. Finally, experiments are carried out to verify both the theoretical analyses and the prototype performance. This study proposes a new approach to designing wheel-leg platforms with prominent speed ability and mobility based on a closed-chain mechanism.
LncRNA GATA6-AS inhibits cancer cell proliferation and promotes cancer cell apoptosis in cervical cancer by down-regulating miR-205
Authors: Zhao Xiaoying , Zheng Huzhong , Chen Jun 
Published: November 2020

Abstract

Background
Dysregulated endothelial cell growth is involved in many types of human cancer, including cervical cancer. LncRNA GATA6-AS was reported to regulate endothelial cell growth, suggesting it might involve in cervical cancer. Our study was carried out to explore the involvement of GATA6-AS in cervical squamous cell carcinoma (CSCC), a subtype of cervical cancer.

Methods
To explore the expression of GATA6-AS, RT-qPCR was performed to detect GATA6-AS in plasma of 65 CSCC patients and 58 healthy females. To detect the expression of GATA6-AS, total RNAs were extracted.

Results
We found that plasma GATA6-AS expression was down-regulated in CSCC patients than that in healthy females, and HPV infection did not significantly affect the plasma expression of GATA6-AS. Moreover, we found that plasma GATA6-AS showed diagnostic values for CSCC by performing ROC curve analysis. The expression of miR-205 in plasma was also found to be up-regulated in CSCC patients than that in healthy females and inversely correlated with the expression of GATA6-AS in CSCC patients. Furthermore, over-expression of miR-205 did not significantly affect the expression of GATA6-AS in CSCC cells, while over-expression of GATA6-AS down-regulated miR-205 expression. In addition, GATA6-AS over-expression inhibited CSCC cell proliferation and promoted CSCC cell apoptosis, while miR-205 over-expression played opposite roles and attenuated the effects of GATA6-AS over-expression on CSCC cells.

Conclusion
Taken together, these results suggest that GATA6-AS may inhibit cell proliferation and promote cell apoptosis in CSCC by down-regulating miR-205.
Balint groups and narrative medicine compared to a control condition in promoting students’ empathy
Authors: Lemogne Cédric , Buffel du Vaure Céline , Hoertel Nicolas , Catu-Pinault Annie , Limosin Frédéric , Ghasarossian Christian , Le Jeunne Claire , Jaury Philippe 
Published: November 2020

Abstract

Background
The perceived importance of clinical empathy may decline among students during medical training. Several interventions have been shown to be effective in promoting or preserving medical students’ empathic abilities, such as empathy skills training or Balint groups. Although narrative medicine training shares some features with these interventions, no randomized study to date examined the efficacy of narrative medicine training. This study aimed to assess the effects of Balint groups and narrative medicine training on clinical empathy measured by the self-rated Jefferson’s School Empathy Scale - Medical Student (JSPE-MS©) among fourth-year medical students.

Methods
Students who gave their consent to participate were randomly allocated in equal proportion to Balint groups, narrative medicine training or to the control group. Participants in the intervention groups received either seven sessions of 1.5-h Balint groups or a 2-h lecture and five sessions of 1.5-h narrative medicine training from October 2015 to December 2015. The main outcome was the change in JSPE-MS© score from baseline to one week after the last session.

Results
Data from 362 out of 392 participants were analyzed: 117 in the control group, 125 in the Balint group and 120 in the narrative medicine group. The change in JSPE-MS© score from baseline to follow-up was significantly higher in the Balint group than in the control group [mean (SD): 0.27 (8.00) vs. -2,36 (11.41), t = 2.086, P = 0.038]. The change in JSPE-MS© score in the narrative medicine group [mean (SD): − 0.57 (8.76)] did not significantly differ from the changes in the control group (t = 1.355, P = 0.18) or the Balint group (t = 0.784, P = 0.43). Adjusting for participants’ characteristics at baseline, Balint groups remained associated with better outcomes compared to the control group (β = 2.673, P = 0.030).

Conclusions
Balint groups may promote clinical empathy to some extent among medical students, at least in the short run.