bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing competitiveness in the tourism industry through the use of business intelligence: a literature review
Authors: Nyanga Christopher , Pansiri Jaloni , Chatibura Delly 
Published: November 2019

Purpose
The purpose of this paper is to demonstrate the relevance of business intelligence (BI) in businesses in general and tourism firms in particular. BI has been hailed as an innovation that can propel businesses that adopt the system to high productivity and efficiency. This paper confirms that view but further adds that BI also enhances a business’s competitiveness.

Design/methodology/approach
This paper reviews literature on the use of BI in tourism. Although current literature is largely fragmented, focusing on BI, the tourism industry and the notion of competitiveness separately, this paper makes an attempt to bring the three sub-themes in the same study and highlights their interconnectedness. The study adopts two environmental analysis models to better analyze this matter. First is the environmental analysis model as based on Downes’s modification of Porter’s five forces framework. The second model used is the resource-based view approach to business environmental analysis.

Findings
This paper affirms that the tourism industry is one of those industries that continue to benefit from the advantages that come with the adoption of a BI system. Literature shows that the tourism industry was one of those that first adopted BI in order to benefit from the benefits that come with its adoption. Such advantages include flexible and user friendly tourists’ data capture, storage, retrieval, processing and analytical capabilities.

Research limitations/implications
This was a largely literature review-based study. There is, therefore, room for strengthening its findings by conducting field work and mixed methods research for more robust results.

Practical implications
This study will surely benefit the tourism industry and business in general from its highly favorable conclusions to the benefits that come with the adoption of a BI system. It can also be used as a reference in to the tourism field, especially aggregating important concepts and literature that can help future practical studies.

Social implications
Society will also benefit from this study in terms of the new knowledge that has been generated. Members of society will then be in a position to demand products and services that are a result of innovation and informed decision making.

Originality/value
Although this paper is largely based on literature, the conclusions reached are those of the authors. A close assessment of the literature in BI and the tourism industry was done, resulting in the conclusions reached by the authors.
B(u)y the book: evaluation of a university initiative to provide students with funds to buy books
Authors: Porritt Frances , Murphy Linda , Wells Gemma , Burns Emma 
Published: November 2019

Purpose
In the era of high student fees and intense market competition, many universities now buy books for their new students, and recently have incorporated student choice into the offer, enabling students to choose how to spend funds. Teesside University has successfully piloted such an approach with one academic School, the School of Social Sciences, Humanities and Law. The pilot has now been extended to all academic Schools, with all students receiving £100 per academic year to spend on reading list books. The scheme covers new full-time undergraduate students at the University, and is operated in collaboration with an external company, John Smiths. The purpose of this paper is to evaluate the Teesside University Advance scheme against baseline data of book borrowing and reservation patterns of reading list titles. The paper explores the impact upon the student experience and student perceptions of the Library.

Design/methodology/approach
The project used a mixed methods approach. The quantitative strand analysed book borrowing and reservation patterns data from library systems and from book purchasing patterns data provided by the online store supporting the scheme. Students were also surveyed about the scheme. The qualitative strand, via one-to-one interviews conducted by the student researcher, gained an insight into why students select certain titles to purchase; and what their expectations of the university library are for the supply of reading list titles.

Findings
Analysis revealed an overall decline in book borrowing from the library of the titles selected for purchase by students via the scheme. Student perceptions of the library were positive and demonstrated a strategic use of library resources alongside book purchases and open web resources. At early stages of university undergraduate study, students need guidance on most appropriate resources to use and why, from either reading lists or book bundles.

Originality/value
Teesside University scheme is unique in the UK in covering all new full-time undergraduates and letting them choose which reading list titles to buy with the university funds provided.
Effect of travel distance and rurality of residence on initial surveillance for hepatocellular carcinoma in VA primary care patient with cirrhosis
Authors: Rodriguez Villalvazo Yolanda , McDanel Jennifer S. , Beste Lauren A. , Sanchez Antonio J. , Vaughan‐Sarrazin Mary , Katz David A. 
Published: November 2019

AbstractObjectiveTo determine the relationship between travel distance and surveillance for hepatocellular carcinoma among veterans with cirrhosis.Data SourcesVeterans Health Administration (VHA) inpatient and outpatient administrative data were linked to geocoded enrollee files. CMS‐VHA merged data were used to assess receipt of Medicare‐financed non‐VA imaging.Study DesignA retrospective cohort of US veterans diagnosed with cirrhosis between 2009 and 2015 was examined. First available abdominal imaging following the diagnosis of cirrhosis was analyzed separately as a function of travel distance to the nearest VA medical center (VAMC) and to the patient's assigned VA primary care provider. Veterans with dual use of Medicare and VA services were also examined for receipt of imaging outside of the VA.Principal FindingsVeterans who resided more than 30 miles from the nearest VAMC were less likely to receive any imaging for HCC surveillance. Among dual users, increased travel distance between the patient's residence and nearest VAMC was associated with an increased likelihood of receiving any abdominal imaging at non‐VA facilities.ConclusionIncreased travel distance to the nearest VA medical center reduces the likelihood of receiving imaging for HCC surveillance in cirrhotic veterans. Future efforts should focus on reducing geographic barriers to HCC surveillance.
Authentication of Tokaj Wine (Hungaricum) with the Electronic Tongue and Near Infrared Spectroscopy
Authors: Zaukuu John‐Lewis Z. , Soós János , Bodor Zsanett , Felföldi József , Magyar Ildikó , Kovacs Zoltan 
Published: November 2019

AbstractTokaj wines (Hungaricum) are botrytized wines acknowledged for the unique organoleptic properties bestowed by botrytized grape berries during production. Excluding these berries during wine production or manipulating the sugar content of low‐grade wines to imitate high‐grade wines are some recent suspicious activities that threaten the wine quality. Advanced methods such as spectroscopy and sensor‐based devices have been lauded for rapid, reliable, and cost‐effective analysis, but there has been no report of their application to monitor grape must concentrate adulteration in botrytized wines. The study aimed to develop models to rapidly discriminate lower grade Tokaj wines, “Forditas I” and “Forditas II,” that were artificially adulterated with grape must concentrate to match the sugar content of high‐grade Tokaj wines using an electronic tongue (e‐tongue) and two near infrared spectrometers (NIRS). Data were evaluated with the following chemometrics: principal component analysis (PCA), discriminant analysis (LDA), partial least square regression (PLSR), and aquaphotomics (a novel approach). There was a noticeable pattern of separation in PCA for all three instruments and 100% classification of adulterated and nonadulterated wines in LDA using the e‐tongue. Aquagrams from the aquaphotomics approach showed important water absorption bands capable of being markers of Tokaj wine quality. PLSR models showed coefficient of determination (R2CV) of 0.98 (e‐tongue), 0.97 (benchtop NIRS), 0.87 (handheld NIRS), and low root mean squared errors of cross‐validation. All three instruments could discriminate, classify, and predict grape must concentrate adulteration in Tokaj with a high accuracy and low error. The methods can be applied for routine quality checks of botrytized wines.Practical ApplicationTokaj wines (Hungaricum) are botrytized wines acknowledged for the unique organoleptic properties bestowed by botrytized grape berries during production. Excluding these berries during wine production or manipulating the sugar content of low‐grade wines to imitate high‐grade wines are some recent suspicious activities that threaten the wine quality. Using advanced instruments, the electronic tongue, benchtop near infrared spectroscopy, and a handheld near infrared spectroscopy, we could discriminate, classify, and predict grape must concentrate adulteration in Tokaj with a high accuracy and low error. The models in our study can be applied for routine quality checks of botrytized wines.
Prevalence, correlates, and impact of sleep disturbance in Chinese patients with primary Sjögren’s syndrome
Authors: Cui Yafei , Li Jing , Li Lin , Zhao Qian , Chen Shengnan , Xia Ling , Fu Ting , Ji Juan , Gu Zhifeng 
Published: November 2019

AbstractAimSleep disturbances are common in primary Sjögren's syndrome (pSS) patients and may lead to disease aggravation and decreased health‐related quality of life (HRQoL). There are currently no known reported studies related to the prevalence, correlates, and impact of sleep disturbance in pSS patients from China. Therefore, this study aims to assess the sleep quality in Chinese pSS patients and evaluate its relationship with the disease activity, quality of life and mood disorders.MethodsA self‐report survey was administered to 221 pSS patients and 198 healthy individuals using the Pittsburgh Sleep Quality Index (PSQI) for sleep quality. Disease activity and damage were evaluated with the European League Against Rheumatism Sjögren's syndrome disease activity index (ESSDAI). Independent samples t tests, Chi‐square analysis, logistic regression were used to analyze these data.ResultsOur results found that the prevalence of poor sleep (PSQI ≥ 6) was 57.5% and the mean global score of PSQI was 6.57 (SD 3.19) in patients, which were significantly higher than the controls (32.3% and 4.93 [SD 2.86], respectively). When trying to fall asleep, patients with pSS had some sleep disturbances, reduced sleep efficiency, increased number of awakenings than controls. There were significant correlations among dryness, ocular surface disease, HRQoL, pain, disease activity, anxiety/depression and sleep quality in pSS patients. Meanwhile, logistic regression models identified depression and Short Form‐36 mental composite score as predictors of poor sleep quality.ConclusionsSleep disturbances are commonly reported in pSS patients and sleep quality is lower in pSS patients than in healthy controls. The data suggested the need for holistic assessment and management of pSS patients.
The Mesopotamian frontier of the Arabian Neolithic: A cultural borderland of the sixth–fifth millennia BC
Authors: Carter Robert 
Published: November 2019

The material culture of coastal Arabian Neolithic sites of the sixth–fifth millennia BC contains a range of small Mesopotamian‐style objects, in addition to Ubaid pottery. There is a significant concentration of such objects at the Kuwaiti sites, H3 and Bahra 1, with lesser amounts in the Central Gulf region and virtually none in the Lower Gulf. The combination of material and symbolic culture at the Kuwaiti sites indicates that their inhabitants could communicate with both Ubaid and Neolithic peoples with equal facility, implying a key role in the region’s earliest experiments in maritime trade. Moreover, the presence in southern Iraq and at Susa of distinctive arrowheads, and possibly Arabian Coarse Ware ceramics, suggests that the range of eastern Arabian Neolithic peoples extended all along the ancient shoreline to the vicinity of the Mesopotamian Ubaid settlements, and even Susiana. The bifacial pressure‐flaked arrowheads are of two different types that are well attested in eastern Arabia, though one type is more common in southern Iraq and Susiana, hinting at a local population related to the Arabian Neolithic. These finds are quantified and illustrated in this paper, and indicate a cultural borderland stretching for around 300 km north of Kuwait.
The short‐term effects of angiotensin II receptor blockers on albuminuria and renal function in Korean patients
Authors: Shin Juyoung , Kim Hun‐Sung , Min Kim Tong , Kim Hyunah , Lee Seung‐Hwan , Hyoung Cho Jae , Lee Hyunyong , Woo Yim Hyeon , Yoon Kun‐Ho 
Published: November 2019

AbstractEach angiotensin II receptor blocker (ARB) asserts independent molecular effects. No study has compared the renoprotective potency of different types of ARBs in Korea. This study evaluated the differences among medications for treating albuminuria. Data were obtained from electronic medical records of adult patients who underwent albuminuria test and received treatment with either angiotensin‐converting enzyme inhibitors (ACEIs) or ARBs between January 2009 and June 2016. Patients' albuminuria and renal function data were observed for three months after treatment initiation. In total, 1475 patients were included. Patients treated with ACEIs had no significant changes in albuminuria (from 127.7 ± 55.1 mg/g to 46.7 ± 18.7 mg/g, P = .127), but those treated with ARBs showed significant improvement (from 491.2 ± 33.2 mg/g to 372.0 ± 28.0 mg/g, P < .001). The ARB group had significantly more patients with normal albuminuria after treatment (from 55.8% to 59.3% for normal albuminuria, from 16.7% to 18.5% for moderately increased albuminuria and from 27.5% to 22.2% for severely increased albuminuria, P = .005), but renal function did not change significantly. Subgroup analysis of ARB types showed that candesartan (from 712.5 ± 71.1 to 489.8 ± 57.8 mg/g, P < .001) and irbesartan (from 522.6 ± 65.7 to 352.6 ± 54.3 mg/g, P < .001) had significant effects. Candesartan improved albuminuria in patients older than 60 years (from 506.9 ± 84.2 to 371.9 ± 70.6 mg/g, P = .004) and irbesartan improved albuminuria in patients with glomerular filtration rate <60 (from 551.6 ± 100.0 to 392.4 ± 76.2, P = .007). Only irbesartan and candesartan could reduce albuminuria, suggesting that all ARBs do not have the same outcome. This indicates the importance of optimizing ARB selection, considering both patient condition and organ‐specific characteristics of medications.
Compromised endothelial function in transgender men taking testosterone
Authors: Gulanski Barbara I. , Flannery Clare A. , Peter Patricia R. , Leone Cheryl A. , Stachenfeld Nina S. 
Published: November 2019

AbstractContextTransgender men (TGM) are persons assigned female gender at birth with a male gender identity and are routinely treated with testosterone. Androgen excess is associated with endothelial dysfunction among cisgender females (CGF) and is an early sign of atherosclerosis and hypertension.ObjectiveTo determine the effect of testosterone treatment on endothelial function in TGM.SettingThe John B. Pierce Laboratory and Yale School of Medicine.SubjectsEleven TGM (age 27 ± 5 years; BMI 24.4 ± 3.7 kg/m2) receiving testosterone (T) and 20 CGF (28 ± 5 years; BMI 26.0 ± 5.1 kg/m2) during the early follicular phase of their menstrual cycle.Design and Outcome MeasuresWe evaluated brachial vasodilatory responses following stimuli designed to elicit shear stress using 5‐minute occlusion to determine endothelial function (flow‐mediated vasodilation, FMD).ResultsTotal T was greater in the TGM compared to CGF (484.6 ± 122.5 vs 1.5 ± 0.7 ng/dL), as was free T (83.9 ± 32.4 vs 1.9 ± 0.8 pg/dL). FMD was markedly lower in the TGM (4.5 ± 2.7%) compared to the CGF (8.1 ± 2.9%, P = .002) indicating significantly diminished endothelial function in TGM.ConclusionsWe have shown for the first time that in TGM the androgen‐dominant hormonal milieu was associated with impaired endothelial function. Endothelial dysfunction precedes clinically detectable atherosclerotic plaque in the coronary arteries, so is an important marker for clinical cardiovascular risk. Therefore, attention to cardiovascular risk factors should be integral to the care of transgender men.
Capturing smart service systems: Development of a domain‐specific modelling language
Authors: Huber Rocco Xaver Richard , Püschel Louis Christian , Röglinger Maximilian 
Published: November 2019

AbstractOver the last years, the nature of service has changed owing to conceptual advances and developments in information technology. These developments have given rise to novel types of service and smart service systems (SSS), ie, resource configurations capable of learning, dynamic adaptation, and decision making. Currently, the internet of things (IoT) is turning physical objects into active smart things, bridging the gap between the physical and the digital world. Smart things advance SSS as they observe the physical environment, access local data, immerse into individuals' everyday lives and organizational routines. In line with the emergent nature of both phenomena, the impact of the IoT on SSS yet needs to be explored. Building the basis for explanatory and design‐led research and for the analysis and design of SSS, a means for the conceptual modelling of SSS that accounts for novel IoT‐enabled concepts is in high need. Hence, we designed, demonstrated, and evaluated a domain‐specific modelling language (DSML) for SSS. We evaluated the DSML by using it in the modelling of real‐world scenarios from all functional IoT domains, by submitting it to the scrutiny of industry experts, by discussing it against generic DSML requirements, and by analysing to what extent it meets domain‐specific design objectives compared with competing artefacts. To demonstrate the DSML, we included a complex real‐world scenario centred around the Nest Learning Thermostat.
Periodontal pathogens and their role in cardiovascular outcome
Authors: Schulz Susanne , Schlitt Axel , Hofmann Britt , Schaller Hans‐Günter , Reichert Stefan 
Published: November 2019

AbstractAimPeriodontitis has been identified as a moderate but independent risk factor for cardiovascular (CV) disease and progression. The objective of this study (ClinicalTrials.gov Identifier: NCT01045070) was to assess subgingival colonization with selected periodontal pathogens on the occurrence of further adverse CV events in a cohort of CV patients.MethodsThe prevalence of severe periodontitis including the detection of 11 periodontal pathogens (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia, Treponema denticola, P. intermdia, Peptostreptococcus micros, Fusobacterium nucleatum, Campylobacter rectus, Eubacterium nodatum, Eikenella corrodens, Capnocytophaga sputigena, Capnocytophaga gingivalis, Capnocytophaga ochracea; HAIN‐Diagnostica®) was analysed in 1,002 CV patients The prognostic impact of periodontal pathogens for combined CV endpoint (stroke/TIA, myocardial infarction, CV death, death from stroke) was evaluated after a 3‐year follow‐up period. Hazard ratios (HRs) were adjusted for established CV risk factors applying Cox regression.ResultsIn the Kaplan–Meier analysis (log‐rank test: p < .001) and Cox regression (HR: 0.545, 95%‐CI: 0.387–0.773; p = .001), the decreased occurrence of E. corrodens was shown to be an independent predictor for adverse CV events after 3 years of follow‐up.ConclusionsThe detection of E. corrodens was associated with a reduced risk of adverse CV events in patients with CV disease. The pathophysiological background underlying this association should be investigated in further studies.
Retrospective study of complications associated with surgically‐placed gastrostomy tubes in 43 dogs with septic peritonitis
Authors: Elmenhorst K. , Pérez López P. , Belch A. , Demetriou J. L. 
Published: November 2019

ObjectivesTo determine the safety of surgically‐placed gastrostomy feeding tubes in dogs with septic peritonitis.Materials and MethodsRetrospective analysis of 43 dogs with septic peritonitis that had undergone surgical exploration and gastrostomy tube (de Pezzer or Foley) placement as part of the surgical procedure. Postoperative recovery times, hospitalisation times, complication rates and overall survival times were documented.ResultsThe most common cause of septic peritonitis was dehiscence of an enterotomy or enterectomy site. Fifteen dogs had a Foley gastrostomy tube placed and 28 had a de Pezzer gastrostomy tube placed. The median time from surgery to the start of enteral nutrition was 16 hours (range 3 to 28 hours). There were no major complications relating to the gastrostomy tube; minor complications occurred in 11 (26%) patients. The overall median time spent in hospital was 5 days (range 3 to 29 days) for patients surviving to discharge and 22 (51%) dogs survived overall.Clinical SignificanceGastrostomy feeding tubes provide a safe way to provide enteral nutrition to dogs with septic peritonitis; they are associated with a low complication rate in these patients.
Influence of dialysate Ca concentrations on the therapeutic effects of etelcalcetide with concomitant drugs in patients with secondary hyperparathyroidism
Authors: Shigematsu Takashi , Fukagawa Masafumi , Yokoyama Keitaro , Akiba Takashi , Fujii Akifumi , Shinoda Atsushi , Akizawa Tadao 
Published: November 2019

AbstractAimSecondary hyperparathyroidism (SHPT), a complication of haemodialysis, is commonly treated with calcimimetics. The impact of dialysates containing different calcium (Ca) concentrations on clinical efficacy of calcimimetics are unclear. We examined whether dialysate Ca concentrations influence the efficacy and dosing of etelcalcetide with concomitant drugs.MethodsWe performed post hoc analyses of a 52‐week, open‐label, multicentre study of etelcalcetide in Japanese SHPT patients to determine whether dialysate Ca influences the therapeutic effects of etelcalcetide with concomitant drugs. We evaluated the differences in serum intact parathyroid hormone (iPTH), corrected Ca (cCa) and phosphate levels among three dialysate Ca concentration groups (2.5, 2.75 or 3.0 mEq/L Ca). Tartrate‐resistant acid phosphatase 5b (TRACP‐5b) and bone alkaline phosphatase (BAP) levels were also compared. Since the dialysate Ca concentration may influence dose adjustment, we assessed the etelcalcetide and concomitant drug doses.ResultsThere were no clinically meaningful differences in iPTH, cCa and phosphate levels among the 2.5, 2.75 and 3.0 mEq/L groups (n = 34, 64 and 35, respectively) over 52 weeks. At Week 52, more than 82%, 71% and 67% of patients had iPTH, cCa and phosphate levels within target ranges (60‐240 pg/mL, 8.4‐10.0 mg/dL and 3.5‐6.0 mg/dL, respectively) across the three groups. TRACP‐5b and BAP levels decreased by Week 52 regardless of dialysate Ca. Changes in etelcalcetide and concomitant drug doses were generally similar in each group.ConclusionThe efficacy and dosing of etelcalcetide with concomitant drugs were essentially unaffected by the dialysate Ca concentration. Patients showed improvements in bone hypermetabolism during treatment.