bluuebunny/crossref_metadata_2025_split huggingface dataset:
Moving Toward Empirically Based Standardization in the Diagnosis of Delayed Ejaculation
Authors: Rowland David L. , Cote-Leger Philippe 
Published: August 2020

Abstract

Background
Criteria for delayed ejaculation (DE) rely on a long ejaculation latency (EL) time, lack of control/advancement regarding ejaculation, and associated bother/distress; yet, few studies have investigated these criteria in men who indicate the desire to ejaculate sooner during partnered sex.

Aim
To help standardize criteria for DE by better understanding characteristics of men who desire to ejaculate sooner during partnered sex in terms of their EL, reported ejaculatory control, and level of bother/distress, as well as their perceptions of typical and ideal ELs for men in general and of ELs for men with premature ejaculation (PE).

Methods
A total of 572 men recruited through social media responded to an online survey regarding their EL, as well as typical, ideal, and PE ELs of men in general. They also rated (i) their ability to control and/or advance ejaculation and (ii) their level of associated bother/distress. 4 comparison groups were then established: men with probable DE (with [DE1] and without [DE2] ejaculatory control issues), a reference group with no ejaculatory disorders, and men who identified as having PE.

Outcomes
To demonstrate differences in EL, ejaculatory control, and bother/distress between men with delayed ejaculation and the control and PE reference groups.

Results
ELs for men with probable DE were twice as long as those with no ejaculatory disorders. When probable DE men were further subdivided into DE2 and DE1, differences were greater for the DE2 group. DE2 men also differed significantly from the reference group on ejaculatory control/advancement but not on bother/distress. Both DE and reference groups differed from the PE group.

Clinical Implications
Using both EL and ejaculatory control are useful in distinguishing men with delayed ejaculation from men without delayed ejaculation.

Strengths & Limitations
A sizable sample drawn from a multinational population powered the study, whereas the use of social media for recruitment limited the generalizability of findings.

Conclusion
Both EL and ejaculatory control differentiate men with probable DE from a control reference group having no ejaculatory disorders. Differences in bother/distress did not emerge as significant. Implications for diagnosing men with DE are presented.
Traumatic Brain Injury Incidence in Adults with Intellectual and Developmental Disabilities
Authors: Seto Katherine , Lloyd Meghann , Chan Vincy , Chung Hannah , Balogh Robert 
Published: August 2020

ABSTRACT:Background:In Ontario, there are approximately 66,000 adults living with a diagnosis of intellectual and developmental disabilities (IDD). These individuals are nearly twice as likely to experience an injury compared to the general population. Falls are an important contributor to injuries in persons with IDD and in the general population, and are consistently found to be the leading cause of traumatic brain injury (TBI). There is currently no literature that quantitatively examines TBI among persons with IDD. The purpose of this study was to compare the risk of TBI for adults with and without IDD in Ontario over time and by demographic information.Methods:Using administrative health databases, two main cohorts were identified: (1) adults with IDD, and (2) a random 10% sample of adults without IDD. Within each cohort, annual crude and adjusted incidence of TBI were calculated among unique individuals for each fiscal year from April 1, 2002 to March 31, 2017.Results:Over the 15-year study period, the average annual adjusted incidence of TBI was approximately 2.8 new cases per 1000 among Ontario adults with IDD, compared to approximately 1.53 per 1000 among those without IDD. In both cohorts, a higher proportion of TBI cases were younger (19–29 years) and male.Conclusions:During the study period, persons with IDD experienced a significantly higher risk of TBI compared to the general population indicating the possibility, and need, for targeted TBI prevention.
The Usefulness of Brief Telephonic Intervention After a Nuclear Crisis: Long-Term Community-Based Support for Fukushima Evacuees
Authors: Horikoshi Naoko , Maeda Masaharu , Iwasa Hajime , Momoi Maho , Oikawa Yuichi , Ueda Yuka , Kashiwazaki Yuya , Onji Miho , Harigane Mayumi , Yabe Hirooki , Yasumura Seiji 
Published: August 2020

ABSTRACTThe Fukushima Daiichi Nuclear Power Station accident in 2011 produced over 100000 evacuees. In order to deal with an increased need of mental health care, brief, transdiagnostic Telephonic Interventions (TI) have been provided for those at risk of different mental health problems identified based on results of the Mental Health and Lifestyle Survey (MHLS). This study aimed to examine usefulness of TI with focusing on evacuees’ subjective estimation assessed in individual follow-up interviews. The sample comprised 484 persons who had been evacuated from 13 municipalities in Fukushima Prefecture to 8 safer regions in and out of Fukushima. We conducted semi-structured interviews for participants receiving TI (intervention group) and those not receiving TI despite being identified as high risk (non-intervention group). The intervention group was older, had a higher proportion of self-reported mental illness, and higher unemployment compared with the non-intervention group. The satisfaction proportion of those who underwent TI was as high as 74.6%. Satisfaction was significantly associated with advance knowledge of TI availability (OR = 3.00, 95% CI: 1.59‐5.64), and advice on health-related practices (OR = 2.15, 95% CI: 1.12‐4.13). Thus, TI is considered to be feasible and useful for public health management practices in major disasters.
A Computational Model for Estimating the Progression of COVID-19 Cases in the US West and East Coast Population Regions
Authors: Yeo Yao-Yu , Yeo Yao-Rui , Yeo Wan-Jin 
Published: August 2020

AbstractThe ongoing coronavirus disease 2019 (COVID-19) pandemic is of global concern and has recently emerged in the US. In this paper, we construct a stochastic variant of the SEIR model to estimate a quasi-worst-case scenario prediction of the COVID-19 outbreak in the US West and East Coast population regions by considering the different phases of response implemented by the US as well as transmission dynamics of COVID-19 in countries that were most affected. The model is then fitted to current data and implemented using Runge-Kutta methods. Our computation results predict that the number of new cases would peak around mid-April 2020 and begin to abate by July provided that appropriate COVID-19 measures are promptly implemented and followed, and that the number of cases of COVID-19 might be significantly mitigated by having greater numbers of functional testing kits available for screening. The model is also sensitive to assigned parameter values and reflects the importance of healthcare preparedness during pandemics.
Cluster randomized trial of an antibiotic time-out led by a team-based pharmacist
Authors: Van Schooneveld Trevor C. , Rupp Mark E. , Cavaleiri R. Jenifer , Lyden Elizabeth , Rolek Kiri 
Published: August 2020

AbstractObjective:Antibiotic time-outs (ATOs) have been advocated to improve antibiotic use without dedicated stewardship resources, but their utility is poorly defined. We sought to evaluate the effectiveness of an ATO led by a team-based pharmacist.Design:Cluster randomized controlled trial.Setting:Six medicine teams at an academic medical facility.Patients:Inpatients who received antibiotics and were cared for by a medicine team.Intervention:In phase A (2 months) pharmacist-led ATOs were implemented on 3 medicine teams (ATO-A) while 3 teams maintained usual care (UC-A). In phase B (2 months), ATOs were continued in the ATO group (ATO-B) and ATOs were initiated in the UC group (UC ATO-B). We targeted 2 ATO points: early (<72 hours after antibiotics were initiated) and late (after the early period but ≤5 days after antibiotic initiation).Results:In total, 290 ATOs were documented (181 early, 87 late, and 22 subsequent) among 538 admissions. The most common ATO recommendations were narrow therapy (148 of 290), no change (124 of 290), and change to oral (30 of 290). ATO initiation was lower in the UC ATO-B group than in either ATO group (21.8% UC ATO-B vs 69.2% ATO-A and -B). Overall antibiotic use was not different between the groups (P = .51), although intravenous (IV) levofloxacin use decreased in the UC group after ATO implementation (49 DOT/1,000 PD vs 20 DOT/1,000 PD; P = .022). The ratio of oral (PO) to intravenous (IV) DOT was lower in the UC group than in any of the ATO groups (P = .032). We detected no differences in mortality, length of stay, readmission, C. difficile infection, or antibiotic adverse events.Conclusions:Implementation of a pharmacist-led ATO was feasible and well accepted but did not change overall antibiotic use. An ATO may promote increased use of oral antibiotics, but more effective strategies for self-stewardship are needed.
Can an infinitely long object fit in an expanding universe?
Authors: Glanville Aaron , Davis Tamara M. 
Published: August 2020

AbstractDoes space stretch its contents as the universe expands? Usually, we say the answer is no—the stretching of space is not like the stretching of a rubber sheet that might drag things with it. In this paper, we explore a potential counterexample—namely, we show that it is impossible to make an arbitrarily long object in an expanding universe, because it is impossible to hold the distant end of the object ‘stationary’ with respect to us (as defined in the Friedmann–Lemaître–Robertson–Walker metric). We show that this does not mean that expanding space has a force associated with it, rather, some fictitious forces arise due to our choice of reference frame. By choosing our usual time slice (where all comoving observers agree on the age of the universe), we choose a global frame that does not correspond to the frame of any inertial observer. As a result, simple relativistic velocity transforms generate an apparent acceleration, even where no force exists. This effect is similar to the fictitious forces that arise in describing objects in rotating reference frames, as in the case of the Coriolis effect.
THE CULT AREA (ZOLNIK) FROM A SCYTHIAN HILLFORT IN CHOTYNIEC NEAR RADYMNO (SOUTHEASTERN POLAND) IN THE CONTEXT OF RADIOCARBON DATING
Authors: Czopek Sylwester , Krąpiec Marek 
Published: August 2020

ABSTRACTA zolnik excavated in 2016–2018 at the hillfort identified as the Scythian cultural circle in Chotyniec (southeastern Poland, 8 km west of the current Poland–Ukraine border) provided a very large quantity of archaeological sources and organic materials. From the latter, 17 samples coming from different horizons were selected for dating and were used to build a chronological model of functioning of the zolnik. Absolute dating is particularly important because the discovered artifacts (especially the most common handmade ceramics) do not show large chronological diversity. The use of the zolnik was estimated at 250–300 years, i.e. between 7th/6th and 4th/3rd century BC. Stratigraphic observations and good references of absolute chronology based on artifacts, including imported Greek ceramics, first in this part of Central Europe, proved to be significant. Older radiocarbon dates correspond to typological dating of Greek amphoras (7th/6th–6th century BC).
Influence of differential structural deformation on shale reservoirs: a case study of the lower Silurian Longmaxi Shale in north Guizhou, Southern China
Authors: Gu Yang , He Jianhua , Xu Sheng , Tian Qianning , Zhang Wei , Yin Shuai 
Published: August 2020

AbstractSouthern China is affected by multi-stage tectonic activities, with strong fold deformation, complex fault systems and poor shale gas preservation conditions. Here, we used shale samples from the lower Silurian Longmaxi shale in the complex tectonic area of Southern China, to study the relationship between differential structural deformation, and pore structure and adsorption capacity. According to the deformation mechanism of the shale, it is further divided into brittle-slip rheological deformation (BD) and ductile-slip rheological deformation (DD). The results show that all micro-fractures can be observed under scanning electron microscopy in deformed shale samples, but in shale samples with different types of rheological deformation, the micro-fractures have large differences in scale, fracture length and lateral connectivity. The micro-fractures developed in DD shales are small in scale and short in fracture length, but have strong local connectivity. In contrast, brittle minerals are more developed in BD shales, and interlayer shearing has formed micro-fractures with large fracture length and good lateral connectivity, which is beneficial for later fracturing. In these two types of deformed shales, pores in organic matter are rare, and sporadic organic pores have small pore size and poor connectivity. The total pore volume (1.8–2.4 × 10−2 cm3 g–1) of BD shale samples is higher than that of DD shale samples (0.8–1.6 × 10−2 cm3 g–1). There is a positive correlation between total pore volume and quartz content. In addition, the specific surface area (12–18 m2 g–1) of DD shale samples is larger than that of BD shale samples (6–12 m2 g–1).
Redescription of the enigmatic jellyfish,Crambionella annandalei(Cnidaria: Scyphozoa) from Indian waters
Authors: Behera Pralaya Ranjan , Jishnudev M. A. , Saravanan Raju , Roul Subal Kumar , Ghosh Shubhadeep , Uma Mahesh V. , Joshi K. K. 
Published: August 2020

AbstractThe catostylid jellyfish,Crambionella annandaleiwas originally described by Rao (1932) based on a preserved specimen collected from the Andaman Sea. Since then, no detailed taxonomic studies have been conducted and the species is often misidentified. Here, we provide a detailed morphological re-description ofC. annandaleifrom fresh material collected at a variety of locations along the east coast of India. The species can be distinguished from its congeners by a combination of morphological characters, the most important of which are the proportion of terminal club length to oral arm length (0.48 ± 0.031), the proportion of the distal portion of the oral arm to naked proximal portion (7.25 ± 0.268) and the body colour. The occurrence of intra-specific colour variation in fresh specimens was also observed in the present study.
The spatial logic of linguistic practice: Bourdieusian inroads into language and internationalization in academe
Authors: Salö Linus 
Published: August 2020

ABSTRACTThis article utilizes Bourdieu's sociology to grasp the relations between linguistic practice and spatiality, and, through that effort, to position language as a pivotal terrain in internationalizing academe. Empirically, it explores Swedish academe and the linguistic practices of its dwellers: Swedish-speaking and non-Swedish-speaking researchers in four disciplines. Here, Swedish co-exists with English as a lingua franca and other languages. Observational and interview data show that this situation gives rise to complex linguistic practices in the workplace, consisting of speakers alternating between Swedish and English or evading other languages. Following Bourdieu, these phenomena manifest in moments when matters of space are rendered salient. They show that linguistic practice is bound up with space to the extent that their interrelationship becomes discernable only when the spatial logic that confines linguistic practices is rejigged. While linguistic practices seemingly operate on a location-based principle, they actually pertain to speakers’ linguistic habitus in relation to the linguistic market conditions in play. (Linguistic practice, space, internationalizing academe)*
The global unmet need of congenital cardiac care: a quantitative analysis of the global burden of disease
Authors: Vervoort Dominique , Cardarelli Marcelo 
Published: August 2020

AbstractBackground:CHDs are one of the most frequent congenital malformations, affecting one in hundred live births. In total, 70% will require treatment in the first year of life, but over 90% of cases in low- and middle-income countries receive no treatment or suboptimal treatment. As a result, CHDs are responsible for 66% of preventable deaths due to congenital malformations in low- and middle-income countries. This study examines the unmet need of congenital cardiac care around the world based on the global burden of disease.Materials and methods:CHD morbidity and mortality data for 2006, 2011, and 2016 were collected from the Institute for Health Metrics and Evaluation Global Burden of Disease Results Tool and analysed longitudinally to assess trends in excess morbidity and mortality.Results:Between 2006 and 2016, a 20.7% reduction in excess disability-adjusted life years and 20.6% reduction in excess deaths due to CHDs were observed for children under 15. In 2016, excess global morbidity and mortality due to CHDs remained high with 14,788,418.7 disability-adjusted life years and 171,761.8 paediatric deaths, respectively. In total, 90.2% of disability-adjusted life years and 91.2% of deaths were considered excess.Conclusion:This study illustrates the unmet need of congenital cardiac care around the world. Progress has been made to reduce morbidity and mortality due to CHDs but remains high and largely treatable around the world. Limited academic attention for global paediatric cardiac care magnifies the lack of progress in this area.
Mayo Normative Studies: Regression-Based Normative Data for the Auditory Verbal Learning Test for Ages 30–91 Years and the Importance of Adjusting for Sex
Authors: Stricker Nikki H. , Christianson Teresa J. , Lundt Emily S. , Alden Eva C. , Machulda Mary M. , Fields Julie A. , Kremers Walter K. , Jack Clifford R. , Knopman David S. , Mielke Michelle M. , Petersen Ronald C. 
Published: August 2020

AbstractObjective:Rey’s Auditory Verbal Learning Test (AVLT) is a widely used word list memory test. We update normative data to include adjustment for verbal memory performance differences between men and women and illustrate the effect of this sex adjustment and the importance of excluding participants with mild cognitive impairment (MCI) from normative samples.Method:This study advances the Mayo’s Older Americans Normative Studies (MOANS) by using a new population-based sample through the Mayo Clinic Study of Aging, which randomly samples residents of Olmsted County, Minnesota, from age- and sex-stratified groups. Regression-based normativeT-score formulas were derived from 4428 cognitively unimpaired adults aged 30–91 years. Fully adjusted T-scores correct for age, sex, and education. We also derived T-scores that correct for (1) age or (2) age and sex. Test-retest reliability data are provided.Results:From raw score analyses, sex explained a significant amount of variance in performance above and beyond age (8–10%). Applying original age-adjusted MOANS norms to the current sample resulted in significantly fewer-than-expected participants with low delayed recall performance, particularly in women. After application of new T-scores adjusted only for age, even in normative data derived from this sample, these age-adjusted T-scores showed scores <40 T occurred more frequently among men and less frequently among women relative to T-scores that also adjusted for sex.Conclusions:Our findings highlight the importance of using normative data that adjust for sex with measures of verbal memory and provide new normative data that allow for this adjustment for the AVLT.
Guidance materials from 2014 to 2019 on nutritional care for Ebola patients in Ebola Treatment Units: an analysis
Authors: Ververs Mija , Vorfeld Cecilia 
Published: August 2020

AbstractObjective:To evaluate the inclusion and exclusion of nutritional content in guidance materials related to nutritional care for hospitalised Ebola Virus Disease (EVD) patients of any age with the aim to provide recommendations for future revised nutritional care guidelines in Ebola Treatment Units (ETU).Design:Qualitative and quantitative analyses of ETU protocols and other guidance materials were conducted. Materials were obtained from practitioners, their organisations and governments active in EVD outbreaks since 2014.Setting:Guinea, Liberia, Sierra Leone and Democratic Republic of Congo.Results:Guidance materials showed a wide variety of topics. Most contained information on different feeding phases during illness, the use of specialised products, what and how to feed children aged 0–23 months, and meal and snack frequency for different age groups. Most materials lacked guidance on how to assess or accommodate patients’ dietary preferences, how to obtain feedback on nutritional care from patients or how to assess whether patients need feeding support. These aspects are particularly relevant to prevent deterioration of the patients’ nutritional status. There was limited guidance on operational aspects of food preparation and provision.Conclusions:Since 2014, numerous materials have been developed by organisations and governments on nutritional support in ETU. Although every EVD outbreak response must be contextualised because of the complexity of EVD and its case management, it is important to resolve technical differences and to provide comprehensive and more practical guidance. The findings of this study may inform future revised guidelines from normative UN organisations and governments of countries affected by EVD.
Dosimetric and radiobiological evaluation of four radiation techniques in preoperative rectal cancer radiotherapy
Authors: Softa Vasiliki , Kiouvrekis Yiannis , Makridou Anna , Kappas Constantin , Kyrgias George , Theodorou Kiki 
Published: August 2020

AbstractPurpose:To compare tumour dose distribution, conformality, homogeneity, normal tissue avoidance, tumour control probability (TCP) and normal tissue complication probability (NTCP) using 3D conformal radiation therapy (3DCRT), 3- and 4-field intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) in patients with locally advanced rectal cancer.Materials and methods:Twenty-four patients staged T1–3N+M0 with locally advanced rectal cancer underwent neoadjuvant chemoradiation therapy. Four different radiotherapy plans were prepared for each patient: 3DCRT, 3- and 4-field IMRT and VMAT are evaluated for target distribution using CI and homogeneity index (HI), normal tissue avoidance using Dmax, V45, V40, V50 and TCP and NTCP using the Lyman–Kutcher–Burman model.Results:VMAT has better HI (HI = 1·32) and 3DCRT exhibited better conformality (CI = 1·05) than the other radiotherapy techniques. With regard to normal tissue avoidance, all radiotherapy plans met the constraints. Dmax in the 3DCRT plans was statistically significant (p = 0·04) for bladder and no significant differences in V40 and V50. In the bowel bag, no significant differences in Dmax for any radiotherapy plan and V40 was lower in 3DCRT than VMAT (p = 0·024). In the case of femoral heads, 3DCRT has a statistically significant lower dose on Dmax than 4-field IMRT (p = 0·00 « 0·05). VMAT has the biggest TCP (80·76%) than the other three radiotherapy plans. With regard to normal tissue complications, probabilities were shown to be very low, of the order of 10-14 and 10-41 for bowel bag and femoral heads respectively.Conclusions:It can be concluded that 3DCRT plan improves conformity and decreases radiation sparing in the organ at risks, but the VMAT plan exhibits better homogeneity and greater TCP.