bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teungku Dayah Agency and Religious Social Capital on Drug Eradication in Aceh, Indonesia
Authors: Nirzalin Nirzalin , Febriandi Yogi 
Published: May 2020

This article examines the success of religious social capital and the agency of teungku dayah (Islamic scholars who belong to traditional religious school) in the collective drug eradication movement in Ujong Pacu, Lhokseumawe-Aceh, Indonesia. The role of religious social capital in combating the drugs market in global drug policy has been less studied. This study provides a quite different view from most scholars who work for combating drug dealers by engaging participation of religious communities in rural society. The agency of teungku dayah succeeded in mobilizing the villagers due to the social capital that bonded the community based on religious ties. The article used live-in method, observation, in-depth and interviews to build a sociological imagination about the patterns of social practice of the people who become the subject of the research. The researchers lived in one of the villager’s houses, participated in their discussions, listened to the gossip, worshipped with them and were involved in certain jobs carried out by the community members who targeted informants. Using religious social capital, this article argues that teungku dayah effectively used the social and religious capital of the Ujong Pacu community to conduct drug eradication. Religious social capital has strong ties in unifying elements of the people in the same religion, moreover it becomes an energy that keeps motivating the community to run anti-drugs movement and driving out the drug addicts in Ujong Pacu, Lhokseumawe-Aceh.
SYNTHESIS AND CHARACTERIZATION OF NOVEL ORGANOBISMUTH FOR ANTIMICROBIAL AND ANTITUMOR STUDIES
Authors: TRIPATHI DIPTI MANI , KANT RAVI , SRIVASTAVA KRISHNA 
Published: May 2020

Objectives: The major objective of this manuscript is to present synthesis and biomedical screening of some organic derivatives of bismuth having general formula (R3BiL2) by the method reported and characterized with the help of M.P., elemental, I.R., and NMR spectral analysis along with their antimicrobial and in vitro antitumor activity against human breast (MCF-7) and mammary cancer (EVSA-7) cell line.
Methods: All the newly organobismuth having general formula [R3BiL2] were synthesised by the method reported especially using oxidative addition and complexation reactions.
Results: It was found that organobismuth compounds have trigonal bipyramidal structure as per their elemental and spectral analysis and show potentiality as antimicrobial and antitumor agents.
Conclusion: The newly synthesized organobismuth(V)substituted carboxylates were fully characterized chemically to ascertain their structure by sophisticated instrumental and spectral analysis resulted as trigonal bipyramidal structure. The compounds were also screened 1st time for antitumor and antimicrobial studies. The observations clearly indicated that organobismuth carboxylates show potent antimicrobial and antitumor activity.
OBSERVING DRUG UTILIZATION TRENDS OF ANALGESICS IN INDOOR SURGICAL PATIENTS IN TERTIARY CARE TEACHING HOSPITAL
Authors: PARULEKAR VIDISHA VIVEK , BADAR VANDANA AVINASH 
Published: May 2020

Objectives: The objectives of the study were to evaluate and compare the utilization pattern of analgesic use in pre-operative, intraoperative, and post-operative wards of different surgical specialties.
Methods: It was a prospective, cross-sectional, and observational study done for a period of 1 year and the data were obtained from case sheets of 386 patients admitted in surgical wards of the. Data were analyzed according to demography, type of surgery, and the WHO prescribing indicators. The percentage of analgesic prescribed from an essential medicine list or National list of essential medicine (NLEM), common analgesics, and fixed dose combinations (FDC) used in surgery, gynecology, ENT, and orthopedic wards in preoperatively, intraoperatively, and postoperatively, was assessed and the amounts of drugs consumed were converted into the number of daily defined dose (DDD) as per the 2010 version of ATC/DDD index.
Results and Discussion: The female to male ratio of 1.21 and most of patients were in the category of middle-aged adults (49%). On the evaluation of WHO prescribing parameters, it was seen the average number of analgesics prescribed per prescription was 1.26, percentage of injectable analgesics and analgesics prescribed from NLEM were 81.09% and 90.64%, respectively. Perioperatively, injection diclofenac sodium was the most commonly used analgesic and its DDD was 460. The most common FDC used perioperatively was aceclofenac 325mg+serratiopeptidase 15 mg (5.04%) and Drug Controller General of India and the WHO approved FDCs were 80.28% and 75.53%, respectively.
Conclusion: It is necessary to determine the prevalence and severity of post-surgical pain and implementation of standardized pain evaluation and treatment protocols which improve the post-operative patient care in the hospital setting.
ARBEKACIN – A RAY OF HOPE TO FIGHT AGAINST MDR AND XDR GRAM-NEGATIVE BACTERIA IN A SCIENTIFIC AND COST-EFFECTIVE WAY IN INDIAN SCENARIO
Authors: SARKAR SOMA , SARKAR DIPANKAR , NAMHATA ANJUM , SENGUPTA MANIDEEPA 
Published: May 2020

Objective: The objective of the study was to see the in vitro activity of arbekacin, a novel aminoglycoside, against multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacilli (GNB) so that it can become a good alternative as empirical treatment for severe sepsis.
Methods: Identification and antibiotic sensitivity testing of the GNB isolated from the clinical samples were done using the VITEK-II system in a tertiary care hospital, Kolkata. MDR and XDR strains were selected by their definitions and molecular characterization was done by multiplex polymerase chain reaction. The minimum inhibitory concentration (MIC) value of arbekacin was detected by the E-test strip and compared with other aminoglycosides.
Results: A total of 140 drug-resistant strains including ESBL- and carbapenemase-producing GNB were selected for the study. Arbekacin showed reduced values of MIC50 and MIC90 compared to other aminoglycosides for most of the drug-resistant GNB.
Conclusion: Hence, in this drug-resistant era, arbekacin with the advantage of a single daily dose can be used as an empirical choice in severe sepsis as monotherapy or in combination with other antibiotics such as colistin or polymyxin to fight against MDR and XDR bugs.
EVALUATING THE EFFECTIVENESS OF PATIENT EDUCATION TO COPE UP DEPRESSION IN MENOPAUSAL STAGE
Authors: SANKAR U GANAPATHY , R MONISHA , DOSS CHRISTOPHER AMALRAJ VALLABA , RM PALANIVEL 
Published: May 2020

Objectives: The aim of the study was to assess the impact of education to combat depression in the menopausal stage.
Methods: Twenty menopausal women, aged 50–55 years were recruited through convenience sampling procedure from Kancheepuram. Zung self-rating depression scale was administered to all the participants.
Results: It revealed that there was a statistical difference in post-test after education on depression (t=13.413; p= 0.00) on menopausal women.
Conclusion: Depression is the common psychological symptoms that affect the women at menopausal age. The severity is due to a lack of knowledge about the symptoms and a lack of awareness to cope with the psychological symptoms.
MOOD IMPAIRMENTS IN ADULTS WITH DEVELOPMENTAL COORDINATION DISORDER
Authors: SANKAR U GANAPATHY , R MONISHA , DOSS CHRISTOPHER AMALRAJ VALLABA , RM PALANIVEL 
Published: May 2020

Objective: Data on the consequences of adults with developmental coordination disorder (DCD) in their life span is in debate and there is no clear and significant data remains. The current study was done to examine the existence or absence of mood impairments with DCD adults.
Methodology: Beck depression and Spielberger Anxiety Inventories were used as an outcome measure to evaluate the symptoms of anxiety and depression in 20 adults diagnosed with DCD with 20 typically developed peer-group population was used as a control.
Results: After statistical evaluation, it has been proved that adults with DCD experience enhanced symptoms of depression, anxiety than their age-matched peers.
Conclusion: This finding has added evidence that adults with DCD experience psychiatric distress and there is a need for consideration of intervention in DCD.
COMPUTATIONAL DESIGN OF NOVEL ORAL INSULIN CONJUGATES FOR THE DEVELOPMENT OF SOLID ORAL INSULIN DOSAGE FORMS
Authors: REDDY JAYARAMA 
Published: May 2020

Objective: Insulin is used to manage diabetes mellitus by subcutaneous injections regulary, that has become a part of patients life and is distressing for patients. Hence, we anticipate to get rid of the usage of subcutaneous injections completely from the medicine world and would make the diabetic people to say as “farewell to painful injections.”
Methods: Virtual screening method (for selection of carriers), Toxtree tool (for toxicity evaluation of carriers), and discovery studio tool (for pharmacophore designing, absorption, distribution, metabolism, excretion, and toxicity [ADMET] analysis, designing oral insulin conjugates (OICs), and interaction studies between insulin receptor and OICs) were used for proposed study.
Results: We have screened 14 competent drug delivering molecules (DDMs) from seven chemical compound databases. The ADMET and pharmacophoric properties of DDMs were analyzed by drug-informatics’ tools. Consequently, the DDMs were mono, di, and poly conjugated by covalent bonding with various binding sites of monomeric and hexameric form of human insulin and insulin-lispro (Humalog®) individually; and novel OICs were generated. Its binding efficiency and biological activity with insulin-receptor were determined.
Conclusion: Inulin and Vitamin-B1 are the novel, safe, and proficient carriers for oral delivery of insulin. Insulin lispro is the remarkable option for oral delivery than other insulin forms.
EVALUATION OF TOCOLYTIC ACTIVITY OF AQUEOUS SEED EXTRACT OF SYZYGIUM CUMINI ON OXYTOCIN INDUCED PRETERM LABOR
Authors: M RAMASAMY , SEBASTIAN ANU , GEORGE ASHLY MERIN 
Published: May 2020

Objective: The present investigation was aimed to determine the tocolytic activity of the aqueous seed extract of S. cumini (AESC) in animal models.
Methods: The in vitro antioxidant activity of AESC was evaluated by (1, 1-diphenyl-2- picrylhydrazyl (α,α-diphenyl-β-picrylhydrazyl) and (2,2’-azino-bis(3- ethylbenzothiazoline-6-sulfonic acid) ABTS radical scavenging assay which showed the hydrogen donating and free radical scavenging activity of extract that aids in the prevention of preterm labor. In vivo tocolytic activity of AESC was evaluated. The level of in vivo antioxidant parameters such as catalase, superoxide dismutase (SOD) and glutathione was restored in the treated group compared to the control group. The AESC was subjected to pharmacological testing in vitro on a piece of isolated rat uterus previously pretreated with estradiol valerate, concentrations used were 80 mg/ml and 160 mg/ml.
Results: The study showed the promising radical scavenging activity of the extract due to hydrogen-donating ability of the formulation. In the current study, a significant increase in the rate of preterm delivery (PTD) of the control animals was observed when compared with the normal group. The AESC treated group has showed a significant reduction in the rate of PTD which was comparable with the standard treated group as well as the normal group. The study reveals that the extracts have been able to increase the endogenous antioxidant enzyme activities while reducing the lipid peroxidation. The concentrations (80 mg/ml) and (160 mg/ml) produce 50.9% and 70.9 % inhibition, respectively.
Conclusion: The results indicate the presence of active principles in the AESC which may be responsible for the tocolytic activity.
Ocio digital y agenciamiento del bien-estar. Incertidumbre en hogares de clase media
Authors: Unás Camelo Viviam 
Published: May 2020

Este artículo expone los resultados de una investigación cualitativa que estudió la vida cotidiana de un grupo de hogares de clase media en Cali, Colombia. La investigación se propuso relacionar dos aspectos en apariencia inconexos: la incertidumbre, expresada en suerte de inconsistencia posicional, que atraviesa la condición de clase media en el país y la centralidad que el ocio digital tiene en las rutinas de los hogares estudiados. A modo de hipótesis se sugerirá que prácticas comunes a estos hogares, como la renovación frecuente de tecnologías y la asiduidad del ocio digital, pueden entenderse como dispositivos marcadores de distinción de clase y, también, como mecanismos de control sobre el presente y modos de compensar, por la vía de ampliar las condiciones de abundancia, el malestar que genera un futuro incierto. Se espera así develar las tensiones que las capas medias experimentan y las prácticas compensatorias que agencian en tanto estrategias para su bienestar.
Buscando la ruta de la medición-valoración ecológica no monetaria, en la Teoría Tridimensional de la Contabilidad
Authors: Álvarez Álvarez Harold 
Published: May 2020

El presente trabajo se inserta en el proceso de reflexión realizado en el macroprograma de investigación de la Teoría Tridimensional de la Contabilidad, PIT3C, iniciado en 2011, por el Grupo de Investigación en Contaduría Internacional Comparada (GICIC), de la Universidad del Quindío, Colombia. Es de conocimiento general que la contabilidad es una disciplina que se ha desarrollado conceptualmente en los últimos cinco siglos, desde la formulación de Pacciolo, fundamentalmente entre el derecho y la economía.
Esta dependencia la ha forzado a ser una especie de servidumbre de los intereses dominantes planteados desde esas dos poderosas disciplinas, que la han maniatado para establecer sus propias rutas de identificación, reconocimiento y búsqueda de solución a muchos de los auténticos problemas propios de su dominio que, siendo independiente, podría alcanzar, asumiendo así su propio devenir disciplinar.
PENDUGAAN PARAMETER GENETIK PERFORMA PRASAPIH DOMBA GARUT DI UPTD-BPPTDK MARGAWATI GARUT
Authors: A. K. Haya , Anang Asep , Heriyadi Denie 
Published: May 2020

Pengembangan sumber daya genetik ternak lokal penting dilakukan untuk memenuhi permintaan dagingdomba yang tinggi di Indonesia khususnya Jawa Barat melalui kegiatan seleksi bibit unggul Domba garut.Penelitian ini bertujuan untuk mengetahui nilai parameter genetik sifat-sifat prasapih Domba garut. Sifat-sifat yang dianalisis pada penelitian ini yaitu bobot lahir (B0), bobot 30, 60, 90 hari (B30, B60, B90), dan bobot sapih pada 100 hari (B100) Domba garut di UPTD-BPPTDK Margawati Garut yang berasal dari 104 ekor pejantan, 1.809 ekor induk, 2.921 ekor anak domba jantan, dan 2.632 ekor anak domba betina. Total catatan yang dianalisis yaitu 27.019 catatan bobot badan yang terdiri atas 6.559 catatan B0, 5.702 catatan B30, 5.248 catatan B60, 4.843 catatan B90 hari, dan 4.667 catatan B100 Tahun 2012-2019. Analisis data menggunakan Restricted Maximum Likelihood (REML) untuk menduga heritabilitas dengan software Variance Components Estimation (VCE) 6.0, menggunakan model maternal genetic effect (m2) dan lingkungan bersama (c2). Efek tetap yang dimasukkan ke dalam analisis yaitu jenis kelamin dan tipe kelahiran. Hasil penelitian menunjukkan bahwa nilai heritabilitas B0, B30, B60, B90, dan B100 menggunakan model maternal genetic effect dan lingkungan bersama yaitu sebesar 0,133±0,04, 0,108±0,03, 0,099±0,03, 0,122±0,03, 0,123±0,03, artinya nilai-nilai heritabilitas tersebut masuk dalam kategori rendah. Nilai maternal genetic effect dan lingkungan bersama B0, B30, B60, B90, dan B100 Domba garut 0,095±0,03, 0,163±0,03, 0,137±0,03, 0,113± 0,02, 0,115±0,02 dan 0,455±0,16, 0,268±0,13, 0,274±0,13 0,269±0,13 0,278±0,12. Hal ini menunjukkan bahwa pendugaan parameter genetik lebih akurat jika melibatkan maternal genetic effect dan lingkungan bersama.
ANALISIS FINANSIAL USAHA PETERNAKAN BABI DENGAN BERBAGAI JENIS RANSUM (Studi Kasus Peternakan Babi di Desa Jadi Kabupaten Tabanan)
Authors: G. A. Wiranata , Putri B. R. T. , Warmadewi D. A. 
Published: May 2020

Tujuan dari penelitian ini adalah untuk menganalisis pendapatan usaha peternakan babi dengan perlakuanpenggantian pollard dengan dedak padi yang disuplementasi multi mineral vitamin. Rancangan yang digunakan adalah rancangan acak kelompok (RAK) yang terdiri dari 4 perlakuan dan 4 kelompok sebagai ulangan, pengelompokan berdasarkan berat badan babi. Perlakuan yang digunakan adalah ransum yang menggunakan konsentrat komersial dan pollard (A) sebagai kontrol, ransum konsentrat TBN-01 dan pollard (B), ransum konsentrat TBN-01 dan dedak padi (C), ransum konsentrat TBN-01 dan dedak padi dengan suplementasi multi mineral-vitamin pignox (D). Adapun variabel penelitian yakni (1) manajemen pemeliharaan ternak babi meliputi pemilihan bibit, perkandangan, pemberian pakan, tenaga kerja, kesehatan ternak dan pemasaran (2) analisis finansial usaha penggemukan babi meliputi biaya total, penerimaan, laba, R/C ratio (revenue and cost ratio), BEP (Break Event Point). Hasil penelitian menunjukkan bahwa berdasarkan biaya total, usaha peternakan babi dengan perlakuan penggantian pollard dengan dedak padi yang disuplementasi multi mineral vitamin sebesar 0,20% (D) menghasilkan R/C ratio paling besar yakni 1,51 atau persentase keuntungan yakni 51%. Simpulan dari penelitian ini adalah dengan manajemen pemeliharaan yang baik dilihat dari pertambahan bobot badan pada perlakuan D sebesar 23,75 g/ekor dengan R/C ratio 1,51 dan menurunkan biaya produksi sebesar 1,51%.
KADAR ASAM LAKTAT, AMONIA DAN pH SILASE LIMBAH SINGKONG DENGAN PEMBERIAN MOLASES BERBEDA
Authors: Ridwan M. , Saefulhadjar D. , Hernaman I. 
Published: May 2020

Penelitian bertujuan untuk melakukan pengawetan limbah perkebunan singkong dengan menggunakan aditif molases. Penelitian dilaksanakan secara eksperimental dengan menggunakan rancangan acak lengkap yang terdiri dari 4 perlakuan dan 5 ulangan. Data yang dihasilkan dianalisis sidik ragam pada taraf ? = 0,5% dan dilanjutkan dengan uji Duncan. Perlakuan berupa tingkat penggunaan molases pada level 0% (P0), 2% (P1), 4% (P2), dan 6% (P3). Hasil menunjukkan konsentrasi asam laktat meningkat signifikan (P<0,05), sedangkan konsentrasi ammonia menurun seiring dengan meningkatnya penggunaan molases. Hubungan antara asam laktat dengan pH menunjukkan korelasi negatif dengan persamaan regresi adalah y = -0,3634X+6,0886 dan nilai korelasi (r) sebesar 0,65, sedangkan hubungan antara pH dengan kadar ammonia menghasilkan persamaan regresi y = 1,9835X–0,2064 dengan nilai korelasi r yaitu 0,64. Hasil penelitian disimpulkan bahwa molases dapat meningkatkan kadar asam laktat, namun menurunkan nilai pH dan ammonia serta penggunaan sebanyak 2% memberikan proses ensilase yang optimal.
Vitamin D as a factor for improving the quality of life in women after 50 years (literature review)
Authors: Pestrikova Tatyana Yu. , Yurasova Elena A. , Knyazeva Tatyana P. 
Published: May 2020

Relevance. Public health is one of the key factors in the development of the economy and at the same time an objective indicator of quality of life. Currently, the number of women over 50 years old is progressively increasing, and their growing social inclusion will determine the desire for active and healthy longevity. In this regard, the public health policy in the country should follow the path of increasingly large-scale financing of projects of a healthy lifestyle, not concentrating expenses only on medical care.
Aim. Analysis of literature on the feasibility of using vitamin D as a factor that improves the quality of life of women in the perimenopausal period and in menopause.
Materials and methods. To write this review, we searched for domestic and foreign publications in Russian and international search engines (PubMed, eLIBRARY, etc.) over the past 20 years. The review included articles from peer-reviewed literature.
Results. The review outlines a wide range of biological properties of vitamin D involved in the regulation of many important physiological functions. The negative effect of vitamin D deficiency is presented not only on the development of cancer, cardiovascular diseases, but also on the increase in the severity of menopausal syndrome. It has been established that the use of colecalciferol (vitamin D3) in combination with menopausal hormone therapy contributes to the normalization of carbohydrate, lipid and calcium phosphorus metabolism, improves the neuropsychic state of patients, which makes it possible to actively use colecalciferol in routine clinical practice in menopausal syndrome.
Conclusions. Numerous positive effects of colecalciferol (vitamin D3) allow the use of the drug as a means to increase social adaptation, and, consequently, improve the quality of life.
Impacto de las Tecnologías de la Información y la Comunicación (Conectivismo) en la Promoción de Vivienda. Un estudio comparativo en la ciudad de Quito y Portoviejo – Ecuador
Authors: Vaca-Cárdenas Mónica Elva , Ordoñez-Ávila Ermenson Ricardo , Vargas-Estrada Astrid Astromelia , Vaca-Cárdenas Leticia Azucena 
Published: May 2020

La sociedad actual se ha visto influenciada por la proliferación de las tecnologías de la información y comunicación (TIC). La evolución de estas tecnologías ha facilitado el acceso a todo tipo de información provocando un aumento considerable de la interactividad entre personas de distintos lugares del mundo. Adicionalmente, el uso de la tecnología permite ser más eficientes en el uso de recursos, vivienda, mejorar los servicios, y solucionar los transcendentales problemas de los ciudadanos. El ámbito en que esta investigación se enfoca es el impacto de la tecnología en la promoción de vivienda. Consecuentemente, el objetivo de esta investigación es analizar el impacto de las Tecnologías de la Información y la Comunicación (Conectivismo) en la Promoción de Vivienda en la ciudad de Quito y Portoviejo – Ecuador. Esta investigación fue un estudio comparativo entre Quito y Portoviejo. Se aplicó una encuesta dirigida a 319 propietarios de vivienda en venta o en arriendo en la ciudad de Quito y Portoviejo – Ecuador. De las cuales, 232 encuestas fueron realizadas en la ciudad de Quito y 87 encuestas fueron realizadas en la ciudad de Portoviejo. El análisis de resultados se lo realizó aplicando minería de texto y con la utilización de la herramienta estadística del estudio R. Los resultados de esta investigación han demostrado que el uso de medios tecnológicos contribuye predominantemente para ofertar vivienda en las ciudades de Quito y Portoviejo, por parte de propietarios de la misma. Así, se concluye que, las Tecnologías de la Información y la Comunicación (Conectivismo) están impactando la promoción de vivienda en las ciudades de Quito y Portoviejo –Ecuador.
PREDIKSI DAMPAK COVID-19 TERHADAP PENDAPATAN NELAYAN JARING INSANG DI KOTA BENGKULU
Authors: Kholis Muhammad Natsir , Fraternesi  , Wahidin La Ode 
Published: May 2020

Fluktuasi pendapatan nelayan memiliki banyak faktor, ada yang dapat dikendalikan dan ada faktor yang tidak dapat dikendalikan. Salah satu faktor yang diyakini mempengaruhi pendapatan nelayan yaitu pandemi COVID-19. Penelitian dilaksanakan pada Bulan April-Mei 2020 di Kota Bengkulu. Tujuan penelitian ini yaitu untuk memprediksi dampak COVID-19 terhadap pendapatan nelayan jaring insang di Kota Bengkulu. Metode yang digunakan yaitu metode studi kasus dengan menggunakan analisis tren (time series). Hasil penelitian menunjukkan total pendapatan nelayan jaring insang di Kota Bengkulu memiliki garis persamaan Ŷ = 1.899.371 -358562.86 (x). Persamaan tersebut memprediksi tren pendapatan nelayan jaring insang di Kota Bengkulu akan menurun tajam hingga bulan Desember 2020. Dampak dari pandemi COVID-19 sangat dirasakan nelayan akibat turunnya harga penjualan ikan. Nelayan jaring insang diprediksi akan berhutang mulai Bulan Juli 2020 sampai Bulan Desember 2020, dengan prediksi puncak penurunan pendapatan tertinggi dan awal berhutang pada Bulan Juli 2020 dengan persentase sebesar -336%.
Kata kunci: Bengkulu, COVID-19, Jaring Insang, Pendapatan