bluuebunny/crossref_metadata_2025_split huggingface dataset:
Círculos literarios: el poder de la lectura en el desarrollo de competencias
Authors: Pérez Martínez Carmen 
Published: December 2020

El objetivo de este artículoes demostrar la utilidad de los círculos literarios a la hora de desarrollar la competencia comunicativa y las interrelacionadas a ella, como son la lingüística, sociolingüística, discursiva y estratégica, en una actividad que permite al alumno no solo desinhibirse de la formalidad del ámbito académico, sino disfrutar de la literatura en la lengua de aprendizaje. También pone en práctica una conciencia crítica que servirá para trabajar estructuras gramaticales relacionadas con la opinión.
¡Que nadie te quite la palabra! Estrategias para aumentar la disposición a comunicarse en el aula de ELE
Authors: Cordeiro Dayane Monica 
Published: December 2020

: En el aula de lenguas extranjeras, los alumnos disponen de un repertorio lingüístico en proceso de desarrollo, que les impide muchas veces, expresar todo su potencial comunicativo. Y es justo en este contexto, que se observa el impacto más significativo de las variables personales. La decisión de comunicarse que asume el hablante siempre que tiene la oportunidad de hacerlo influye directamente en los logros en su competencia comunicativa en la lengua extranjera. En este sentido, conocer los componentes de la disposición a comunicarse, cómo generarla y mantenerla en el aula pueden ser la clave hacia una enseñanza/aprendizaje de la expresión y la interacción oral más efectiva. El objetivo de este artículo es ofrecer pautas didácticas y metodológicas para aumentar la disposición a comunicarse de los estudiantes a favor de un aprendizaje más efectivo, duradero y experiencial.
Palabras clave: Disposición a comunicarse, didáctica, enseñanza de español lengua extranjera, competencia comunicativa
Influence of Plant Densities and Nitrogen Levels on the Performance of Popcorn Hybrid
Authors: Lakshmi Y. Siva , Sreelatha D. , Pradeep T. 
Published: December 2020

A field experiment was conducted at the Maize Research Centre, Agricultural Research Institute (ARI), Rajendranagar, Hyderabad during the rabid seasons (15 October to 15 January) for two years to study the effect of plant densities and nitrogen levels on growth parameters, yield characteristics, yield and economics of the newly published popcorn hybrid BPCH-6 by Professor Jayashankar Telangana State Agri-6 (Previously Acharya NG Ranga Agricultural University). Three plant densities (P1–1,11,111 ha-1 (60 x 15 cm), P2–1,11,111 ha-1 (45 x 20 cm) and P3–83,333 ha-1 (60 x 20 cm) and four levels of nitrogen (N1–80 kg ha-1, N2–120 kg ha-1, N3–160 kg ha-1 and N4–200 kg ha-1) were taken in a randomised block configuration with three repeated factorial principles. Significantly higher plant height with a population of 1, 11,111 ha-1 (45x20 cm), significantly higher leaf area index with a population of 1, 11,111 ha-1 (60x15 cm) and significantly higher dry matter production (g plant-1) with a population of 83,333 plants ha-1 (60x20 cm) was observed as per pooled mean over two years. Yield attributes like cob girth, number of rows cob-1 and 100 seed weight were not influenced significantly whereas cob length and number of seeds row-1 were significantly superior with optimum plant density of 83,333ha-1. A plant density of 1, 11,111 ha-1 (60x15 cm). recorded significantly higher cob, grain fodder yields.
When a population of 1, 11,111 plants ha-1 (60x15 cm) was maintained, gross and net returns and profit cost ratios were higher. The use of 200 kg of nitrogen ha-1 resulted in slightly higher growth parameters, yield characteristics and yield, but it was equal to 160 kg of N ha-1 and both were greater than 120 and 80 kg of N ha-1.. Application of 160 Kg N ha-1 recorded higher gross and net returns and benefit cost ratio compared to 200 Kg N ha-1.
Performance Evaluation of Drip Irrigation System and Profitability Analysis of Leafy Vegetables under Polyhouse
Authors: Kishore A. , Deshai Nithin , Rathdo R. Savitha , Prakash J. Surya , Lakshmi Y. Siva 
Published: December 2020

The present experiment on Performance evaluation of drip irrigation system and profitability analysis of leafy vegetables under polyhouse was conducted to study the performance parameters of the drip irrigation systems relating to crop performance. This was done by taking existing drip tapeline, new drip tape line and new inline drip irrigation system under the Polyhouse at the college of Agricultural Engineering, Kandi, Sangareddy, Telangana during the year 2018. Profitability of five green leafy vegetables viz. Palak, Sorrel, Methi, Amaranths and Coriander was also evaluated. The results reveal that the three drip line systems in-line got more uniform coefficient of 98% followed by new drip tape with 96% and preinstalled drip tape with 95%. Among the five green leafy vegetables methi has recorded highest gross (306000Rs acre-1) and net returns (285833) and benefit cost ratio (14.2) followed by Palak, Sorrel whereas Amaranthus has recorded lowest benefit cost ratio (7.6). In terms of performance characteristics, drip tape and in line system performed better in maintaining uniformity discharge and the designed drip irrigation operated excellently. Methi, Palak ad sorrel found suitable and profitable in polyhouse where year- round cultivation of vegetables is feasible compared to open field in which crop establishment was very poor and could not be raised successfully due the heavy rains and growth characters of the leafy crops.
Evaluation of technical performance of optical surface imaging system using conventional and novel stereotactic radiosurgery algorithms
Authors: Kojima Hironori , Takemura Akihiro , Kurokawa Shogo , Ueda Shinichi , Noto Kimiya , Yokoyama Haruna , Takamatsu Shigeyuki 
Published: December 2020

AbstractThe Catalyst HD (C‐RAD Positioning AB, Uppsala, Sweden) optical surface imaging (OSI) system is able to manage interfractional patient positioning, intrafractional motion monitoring, and non‐contact respiratory gating without x‐ray exposure for radiation therapy. In recent years, a novel high‐precision surface registration algorithm for stereotactic radiosurgery (SRS algorithm) has been released. This study aimed to evaluate the technical performance of the OSI system using rigid phantoms, by comparing the conventional and SRS algorithms. To determine the system’s technical performance, isocenter displacements were calculated by surface image registration via the OSI system using head, thorax, and pelvis rigid phantoms. The reproducibility of positioning was evaluated by the mean value calculated by repeating the registration 10 times, without moving each phantom. The accuracy of positioning was evaluated by the mean value of the residual error, where the 10 offset values given to each phantom were subtracted from the isocenter displacement values. The stability of motion monitoring was evaluated by measuring isocenter drift during 20 min and averaging it over 10 measurements. For the head phantom, all tests were compared with the mask types and algorithms. As a result, for all sites and both algorithms, the reproducibility, accuracy, and stability for translation and rotation were <0.1 mm and <0.1°, <1.0 mm and <1.0°, and <0.1 mm and <0.1°, respectively. In particular, the SRS algorithm had a small absolute error and standard deviation of calculated isocenter displacement, and a significantly higher reproducibility and accuracy than the conventional algorithm (P < 0.01). There was no difference in the stability between the algorithms (P = 0.0280). The SRS algorithm was found to be suitable for the treatment of rigid body sites with less deformation and small area, such as the head and face.
Assessing learning effort with hand motion tracking methods
Authors: Rheem Hansol , Vaughn Becker D. , Craig Scotty D. 
Published: December 2020

AbstractTechnology has enabled various alternative educational platforms, such as online courses. Compared to human instructors in traditional educational environments, alternative platforms often show a limited capacity to evaluate the learning progress of students and implement intervention strategies based on the evaluation. Here, we tested participants' hand motions, recorded using a computer mouse and a touchscreen, to determine if the data can predict learners' struggles. Hand motions of participants concurrently performing arithmetic and motor tasks were examined to investigate how the hand motions varied depending on the difficulty of the arithmetic task. The results indicated that working memory load affected both the temporal and spatial features of hand motions, which were predictive of participants' level of working memory load. These findings demonstrate that the assessment of struggles in learning may be achieved at relatively high accuracy with input devices commonly used by learners to access online education systems.
How the poor get richer: Signaling guides attention and fosters learning from text‐graph combinations for students with low, but not high prior knowledge
Authors: Richter Juliane , Wehrle Amelie , Scheiter Katharina 
Published: December 2020

AbstractIn multimedia learning, graphs are seen as just one specific instance of pictorial representations requiring the same cognitive processes as realistic depictions. Accordingly, learning from text‐graph combinations should also benefit from the same instructional support such as signaling of text‐picture correspondences depending on learners' prior knowledge. We investigated whether this expertise reversal of the signaling effect could be replicated for text‐graph combinations. Students (N= 101) with different prior knowledge levels learned with text‐graph combinations that were either enhanced with signals or not. Results indicate an expertise reversal effect on learning outcomes. A moderated mediation analysis of students' visual attention showed that this pattern could be explained by the fact that students with low prior knowledge (LPK) fixated the graph information earlier, whereas high prior knowledge students fixated the graph later when signals were present. Our results suggest that instructional support should be adapted to students' prior knowledge.
Examining the role of calibration of executive function performance in college learners' regulation
Authors: Follmer D. Jake 
Published: December 2020

SummaryThis study examined learners' calibration of their executive function performance and the contribution of learners' calibration accuracy to their self‐regulated learning. A measure of calibration bias of EF performance is introduced and an evaluation of the utility of the measure is presented. Direct and indirect measures of EF, an assessment of students' metacognitive strategy use, and academic achievement information were obtained from a sample of 189 college learners. Findings revealed that students who were overconfident in their appraisal of their EF performance obtained significantly higher scores on a criterion self‐report measure of EF. Evaluation of hierarchical regression analyses revealed that learners' ability to monitor their EF performance predicted criterion measures of EF and metacognitive strategy use, and accounted for unique variance in both outcomes after controlling for their academic achievement. The utility of this calibration bias measure as well as implications for future research are discussed.
ADAMTSL2 gene variant in patients with features of autosomal dominant connective tissue disorders
Authors: Steinle Jacob , Hossain Waheeda A. , Lovell Scott , Veatch Olivia J. , Butler Merlin G. 
Published: December 2020

AbstractEhlers‐Danlos syndrome (EDS) consists of a heterogeneous group of genetically inherited connective tissue disorders. A family with three affected members over two generations with features of Dermatosparaxic EDS (dEDS) autosomal dominant transmission was reported by Desai et al. and having a heterozygous nonsynonymous missense variant of ADAMTSL2 (c.1261G > A; p. Gly421Ser). Variation in this gene is also reported to cause autosomal recessive geleophysic dysplasia. We report five unrelated patients with the Gly421Ser variant identified from a large series of patients presenting with features of connective tissue disorders, each with a positive family history consistent with autosomal dominant transmission. Clinical features of a connective tissue disorder included generalized joint hypermobility and pain with fragility of internal and external tissues including of skin, dura, and arteries. Overall, our analyses including bioinformatics, protein modeling, and gene‐protein interactions with the cases described would add evidence for the Gly421Ser variant in ADAMTSL2 as causative for variable expressivity of autosomal dominant connective tissue disorders.
Vertical transmission of a large calvarial ossification defect due to heterozygous variants of ALX4 and TWIST1
Authors: Walters Michelle E. , Lacassie Yves , Azamian Mahshid , Franciskovich Rachel , Zapata Gladys , Hernandez Patricia P. , Liu Pengfei , Campbell Ian M. , Bostwick Bret L. , Lalani Seema R. 
Published: December 2020

AbstractALX4 is a homeobox gene expressed in the mesenchyme of developing bone and is known to play an important role in the regulation of osteogenesis. Enlarged parietal foramina (EPF) is a phenotype of delayed intramembranous ossification of calvarial bones due to variants of ALX4. The contrasting phenotype of premature ossification of sutures is observed with heterozygous loss‐of‐function variants of TWIST1, which is an important regulator of osteoblast differentiation. Here, we describe an individual with a large cranium defect, with dominant transmission from the mother, both carrying disease causing heterozygous variants in ALX4 and TWIST1. The distinct phenotype of absent superior and posterior calvarium in the child and his mother was in sharp contrast to the other affected maternal relatives with a recognizable ALX4‐related EPF phenotype. This report demonstrates comorbid disorders of Saethre‐Chotzen syndrome and EPF in a mother and her child, resulting in severe skull defects reminiscent of calvarial abnormalities observed with bilallelic ALX4 variants. To our knowledge this is the first instance of ALX4 and TWIST1 variants acting synergistically to cause a unique phenotype influencing skull ossification.
Review of clinical and molecular variability in autosomal recessive cutis laxa 2A
Authors: Morlino Silvia , Nardella Grazia , Castellana Stefano , Micale Lucia , Copetti Massimiliano , Fusco Carmela , Castori Marco 
Published: December 2020

AbstractATP6V0A2‐related cutis laxa, also known as autosomal recessive cutis laxa type 2A (ARCL2A), is a subtype of hereditary cutis laxa originally characterized by skin, skeletal, and neurological involvement, and a combined defect of N‐glycosylation and O‐glycosylation. The associated clinical spectrum subsequently expanded to a less severe phenotype dominated by cutaneous involvement. At the moment, ARCL2A was described in a few case reports and series only. An Italian adult woman ARCL2A with a phenotype restricted to skin and the two novel c.3G>C and c.1101dup ATP6V0A2 variants has been reported. A systematic literature review allowed us to identify 69 additional individuals from 64 families. Available data were scrutinized in order to describe the clinical and molecular variability of ARCL2A. About 78.3% of known variants were predicted null alleles, while 11 were missense and 2 affected noncanonical splice sites. Age at ascertainment appeared as the unique phenotypic discriminator with earlier age more commonly associated with facial dysmorphism (p .02), high/cleft palate (p .005), intellectual disability/global developmental delay (p .013), and seizures (p .024). No specific genotype–phenotype correlations were identified. This work confirmed the existence of an attenuated phenotype associated with ATP6V0A2 biallelic variants and offers an updated critique to the clinical and molecular variability of ARCL2A.
Confirming the involvement of PIEZO2 in the etiology of Marden–Walker syndrome
Authors: Seidahmed Mohammed Zain , Maddirevula Sateesh , Miqdad Abeer M. , Al Faifi Abdullah , Al Samadi Abdulmohsen , Alkuraya Fowzan S. 
Published: December 2020

AbstractPathogenic heterozygous variants in PIEZO2 typically cause distal arthrogryposis type 5 (DA5) and the closely related Gordon syndrome (GS). Only one case of PIEZO2‐related Marden–Walker syndrome (MWS) has been reported to date. We report the phenotypic features of a Saudi female patient with features consistent with MWS in whom we identified a novel de novo likely pathogenic variant in PIEZO2. Our case lends support to the link between PIEZO2 and MWS.
Increased dental fluctuating asymmetry is associated with active skeletal lesions, but not mortality hazards in the precontact Southwest United States
Authors: O'Donnell Lexi , Moes Emily 
Published: December 2020

AbstractObjectiveThis study examines whether individuals with higher dental fluctuating asymmetry (DFA) are frailer than those with lower DFA, by examining whether increased DFA is associated with skeletal lesion formation.Subjects and methods150 individuals with permanent teeth and 64 individuals with deciduous teeth. All individuals are Ancestral Puebloans from archaeological sites in modern‐day New Mexico. We estimate DFA in three ways: (a) deciduous DFA only, (b) permanent DFA only, and (c) a composite of permanent and deciduous DFA. We analyzed DFA alongside lesion status for cribra orbitalia (CO) and porotic hyperostosis (PH), as well as the presence/absence of enamel hypoplasia (EH). All stress indicators were further analyzed for their impact on mortality hazards.ResultsWe find that individuals with active CO and PH lesions have increased DFA, while those with healed lesions have lower DFA. We found no relationship between EH and DFA. Further, DFA alone does not predict individual mortality but CO does.ConclusionsIndividuals with increased DFA are frailer and therefore, less capable of buffering themselves against perturbations to their health than those with lower DFA. All results indicate that individuals in this study with lower DFA were more successful in buffering themselves against random environmental impacts during childhood. While DFA alone does not predict mortality hazard, its relationship to lesion status (lower DFA in individuals with healed lesions) indicates that it would be a valuable addition to studies of health and stress.
CD8+ T‐Lymphocyte–Driven Limbic Encephalitis Results in Temporal Lobe Epilepsy
Authors: Pitsch Julika , van Loo Karen M. J. , Gallus Marco , Dik Andre , Kamalizade Delara , Baumgart Ann‐Kathrin , Gnatkovsky Vadym , Müller Johannes Alexander , Opitz Thoralf , Hicking Gordon , Naik Venu Narayanan , Wachsmuth Lydia , Faber Cornelius , Surges Rainer , Kurts Christian , Schoch Susanne , Melzer Nico , Becker Albert J. 
Published: December 2020

ObjectiveLimbic encephalitis (LE) comprises a spectrum of inflammatory changes in affected brain structures including the presence of autoantibodies and lymphoid cells. However, the potential of distinct lymphocyte subsets alone to elicit key clinicopathological sequelae of LE potentially inducing temporal lobe epilepsy (TLE) with chronic spontaneous seizures and hippocampal sclerosis (HS) is unresolved.MethodsHere, we scrutinized pathogenic consequences emerging from CD8+ T cells targeting hippocampal neurons by recombinant adeno‐associated virus‐mediated expression of the model‐autoantigen ovalbumin (OVA) in CA1 neurons of OT‐I/RAG1−/− mice (termed "OVA‐CD8+ LE model").ResultsViral‐mediated antigen transfer caused dense CD8+ T cell infiltrates confined to the hippocampal formation starting on day 5 after virus transduction. Flow cytometry indicated priming of CD8+ T cells in brain‐draining lymph nodes preceding hippocampal invasion. At the acute model stage, the inflammatory process was accompanied by frequent seizure activity and impairment of hippocampal memory skills. Magnetic resonance imaging scans at day 7 of the OVA‐CD8+ LE model revealed hippocampal edema and blood–brain barrier disruption that converted into atrophy until day 40. CD8+ T cells specifically targeted OVA‐expressing, SIINFEKL‐H‐2Kb–positive CA1 neurons and caused segmental apoptotic neurodegeneration, astrogliosis, and microglial activation. At the chronic model stage, mice exhibited spontaneous recurrent seizures and persisting memory deficits, and the sclerotic hippocampus was populated with CD8+ T cells escorted by NK cells.InterpretationThese data indicate that a CD8+ T‐cell–initiated attack of distinct hippocampal neurons is sufficient to induce LE converting into TLE‐HS. Intriguingly, the role of CD8+ T cells exceeds neurotoxic effects and points to their major pathogenic role in TLE following LE. ANN NEUROL 2021;89:666–685
Arachidonic acid‐encapsulated microcapsules with core‐shell structure prepared by coaxial electrospray
Authors: Hu Meng‐Xin , Chen Xian‐Lin , Song Li‐Jie , He Fei 
Published: December 2020

AbstractArachidonic acid (AA) is an n‐6 polyunsaturated 20‐carbon fatty acid taking important immunomodulatory roles in infant growth, brain development, and health. However, one of the major drawbacks of polyunsaturated fatty acids is their high susceptibility to oxidation followed by unpleasant odors. Microencapsulation has been proposed as an excellent strategy to solve these problems. In this work, coaxial electrospray was utilized to fabricate AA/zein microcapsules with core‐shell structures which were verified by scanning electron microscopy, transmission electron microscopy, and confocal laser scanning microscopy. Microcapsules morphology was conveniently controlled through electrospray parameters and AA was centralized in the core. The microcapsule diameter ranged from 1 to 7 μm. Results of peroxide values and GC–MS demonstrated that AA in microcapsules possess improved oxidative stability and the unpleasant odors of AA oil was inhibited. The results indicate coaxial electrospray is a useful and convenient tool to fabricate core‐shell microcapsules with immiscible materials, which will broaden the potential use of microcapsules as nutrition fortifiers in the food industry.
Self‐healable MnO2‐cured polysulfide sealant and the effect of fillers on its self‐healing ability
Authors: Gao Wentong , Li Shuhang , Cao Xiao , Li Wen , Han Bing 
Published: December 2020

AbstractMnO2‐cured polysulfide sealants have been widely used in various industrial fields and the effects of MnO2 and three fillers on their mechanical behavior, thermal property and self‐healing ability were focused on in this paper. Under a moderate thermal stimulus, the tensile strength can be significantly restored due to the dynamic exchange of disulfide bonds in polysulfide segments. The residue of a small dosage of thiol promotes the healing process of polysulfide sealants. After healing at 75°C for 48 h, the tensile strength of 2 wt% MnO2 cured sealant is restored to more than 90%. Then, this sealant is modified with three fillers to enhance the tensile strength, however, the addition of fillers hinder the healing process to some extent. Significantly, the sealant modified with 2.5 wt% TiO2 can perform a certain enhancement without sacrificing the healing mechanical properties. These outcomes are helpful for the development of MnO2‐cured polysulfide sealants toward sustainable industrial applications.