bluuebunny/crossref_metadata_2025_split huggingface dataset:
GOLD APPLIQUES AFFIXED TO THE WOODEN BOWLS FROM THE PERESCHEPINE BURIAL GROUND NEAR BELSK
Authors: Makhortykh S. V. 
Published: February 2020

The article is devoted to the analysis of gold plaques on wooden vessels from the Pereshchepino cemetery near Belsk, which are among the brightest indicators of Scythian culture and mark the distribution of this category of funeral equipment in the Dnieper forest-steppe Left Bank in the middle — second half of the 5th century BC. Items considered are represented by several subject-stylistic groups, among which there are plaques decorated with geometric patterns (a double row of convex points), and plaques with various zoomorphic motifs (recumbent stag, head of a bird of prey). The images differ in local specificity and have an original interpretation of individual details. First of all, it concerns the motif of recumbent stag, which demonstrate iconographic dynamics and with the involvement of materials from neighboring territories indicate the formation in the «late» V — first decades of the 4th centuries BC a «forest-steppe» type of images of this animal. Objects of animal style from forest-steppe areas of Ukraine are an important component of the Scythian art of Eastern Europe and must be taken into account when analyzing the genesis of this phenomenon.
DEPOSITS OF BRONZE SMALL TWIGS IN MIDDLE ROS BASIN
Authors: Romanuik V. V. 
Published: February 2020

In the article the noticeable role of bronzocasting production is considered on the settler monuments of scythian time in the Tarashchanskiy district of the Kyiv area.
Among the numerous testimonies of bronze casting production and trade in metals the two most interesting items are bronze treasures, recently discovered in the villages of Lisovichi and Dibrovka in Kyiv region. Each contained about 300 bars with a length of 40.5 and 22 cm (Lisovichi), 41 cm (Dibrovka), total weight about 30 kg. We can assume a different purpose of bronze bars: blanks for specific products, raw materials for smelting, the equivalent of money. Spectral analysis of the products showed that they are made of high-quality tin bronze with a high admixture of iron (2.58 %, Lisovichi). Titanium content (4.39 %, Lisovichi) remains unclear (is it a natural impurity in raw materials?) According to the place of discovery (on settlements), treasures of bars can be dated to Scythian time (the end of 6th—5th century BC?), although more late dates are not excluded.
Copper-nickel oxide nanofilm modified electrode for non-enzymatic determination of glucose
Authors: Hasanzadeh Mahsa , Hasanzadeh Zahra , Alizadeh Sakineh , Sayadi Mehran , Nasiri Nezhad Mojtaba , Sabzi Reza Emamali , Ahmadi Sajjad 
Published: February 2020

CuxO-NiO nanocomposite film for the non-enzymatic determination of glucose was prepared by the novel modifying method. At first, anodized Cu electrode was kept in a mixture solution of CuSO4, NiSO4 and H2SO4 for 15 minutes. Then, a cathodization process with a step potential of -6 V in a mixture solution of CuSO4 and NiSO4 was initiated, generating formation of porous Cu-Ni film on the bare Cu electrode by electrodeposition assisted by the release of hydrogen bubbles acting as soft templates. Optimized conditions were determined by the experimental design software for electrodeposition process. Afterward, Cu-Ni modified electrode was scanned by cyclic voltammetry (CV) method in NaOH solution to convert Cu and Ni nanoparticles to the nano-scaled CuxO-NiO film. The electrocatalytic behavior of the novel CuxO-NiO film toward glucose oxidation was studied by CV and chronoamperometry (CHA) techniques. The calibration curve of glucose was found linear in a wide range of 0.04–5.76 mM, with a low limit of detection (LOD) of 7.3 µM (S/N = 3) and high sensitivity (1.38 mA mM-1 cm-2). The sensor showed high selectivity against some usual interfering species and high stability (loss of only 6.3 % of its performance over one month). The prepared CuxO-NiO nanofilm based sensor was successfully applied for monitoring glucose in human blood serum and urine samples.
Settlement Service Literacy and the Relationship Between Service Utilisation and Wellbeing Among Newly Arrived Migrants: A Mixed Methods Systematic Review Protocol
Authors: Woodward Kerry , Polonsky Michael , Green Julie , Abood Julianne , Renzaho Andre 
Published: February 2020

Background: Settlement service literacy refers to the ability of migrants to access, understand and critically navigate settlement services. In Australia, increasing numbers of culturally and linguistically diverse migrants require settlement services to assist their transition. However, there are barriers to migrant’s ability to utilise settlement services which are related to their level of settlement service literacy. This review aims to shed light on how settlement service literacy influences new migrant’s utilisation of settlement services, and the consequences that it has for health, well-being and sense of belonging.
Methods: The review will follow the guidelines laid out by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Literature searches will be undertaken in CINAHL, EMBASE, PubMed, PsycINFO, Scopus, Web of Science, Sociological Abstracts, SocIndex, ProQuest Social Science Database, and Google Scholar. Grey literature and relevant government bodies, non-government organisations, service providers and research institutes will also be searched. Studies included will report primary data (qualitative and quantitative) on new migrant’s (under five years) ability to utilise settlement services in high income countries. Studies that meet the inclusion criteria will be imported to Covidence, two researchers will screen the studies in a two part process (title and introduction scan; and full text) for relevance. Data extracted will include general publication information (author, country, year, and publication), type of study, participants, type of settlement service, measured outcomes, and the study aims, methods and results. Finally, data will be synthesised using a narrative approach.
Discussion: The review will provide insight into the relationship between settlement service literacy and service utilisation and wellbeing for new migrants. The review will also provide data to inform settlement service policy to better cater for the needs of migrants.
Systematic review registration:This protocol has been submitted to international prospective register of systematic reviews and meta-analysis (PROSPERO) and is currently under review.
Cefotaxime vs Ceftriaxone for the Management of Preterm Premature Rupture of Membranes
Authors: Rasti Shinta Dewi , Rochmanti Maftuchah , Primariawan Relly Yanuari 
Published: February 2020

Introduction: Antibiotics are well known and recommended as the main therapy for preterm premature rupture of membranes (PPROM.) But the research on antibiotics other than the recommended macrolides regimens is still lacking. This research aims to evaluate whether there are effects differences of cefotaxime and ceftriaxone given on pregnancy with PPROM by comparing the duration of the latency period and the infants outcomes.
Material and Methods: Data was taken retrospectively through medical records at Dr. Soetomo Surabaya General Hospital, Indonesia during the period of January-December 2017. The inclusion criteria were a history of PPROM in pregnancy <37 weeks, given cefotaxime or ceftriaxone therapy, and have labor data. The analysis was performed by the Mann-Whitney comparison test for the latency period and Fisher's exact test for infant outcomes.
Results: There were 52 samples obtained. The antibiotics used were cefotaxime 3x1gr (A) and ceftriaxone 2x1gr (B). The results of the analysis showed that there were no significant differences between the types of antibiotics with the length of the latency period, with a value of p = 0,601 (p>0,05), where group A had a median of 52,67 hours and group B was 34,17 hours. Group A was found to be more able to extend the latency period for >48 hours with a percentage of 57,8%, whereas in group B only 42,9%. There are no significant differences in infant outcomes; infant birth weight and Apgar score among the two therapies used.
Conclusion: Cefotaxime was more preferably to be used in the Dr. Soetomo Surabaya General Hospital. Nevertheless, ceftriaxone can still be a good choice for PPROM therapy since both cephalosporins have succeeded in preventing infections in women with PPROM.
Does percutaneous transthoracic needle biopsy increase the risk of pleural recurrence in patients with stage I lung cancer?
Authors: Cheng Diou , Wang Zihuai , Cui Jian , Liu Lunxu 
Published: February 2020

Abstract
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was: does percutaneous transthoracic needle biopsy (PTNB) increase the risk of pleural recurrence in patients with stage I lung cancer? Altogether, 298 papers were found using the reported search, of which 7 cohort studies and 1 meta-analysis represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers were tabulated. Four cohort studies suggested an association between PTNB and pleural recurrence in patients with stage I lung cancer, while the other 3 cohort studies found that PTNB had no impact. One meta-analysis (the largest study) including 5 of the cohort studies above concluded that PTNB increased the risk of pleural recurrence among patients with stage I lung cancer with subpleural lesions. Based on the available evidence, it was suggested that there may be an association between PTNB and pleural recurrence in patients with stage I lung cancer, especially for patients with subpleural lesion.
Correlated Evolution of Large DNA Fragments in the 3D Genome of Arabidopsis thaliana
Authors: Yan Yubin , Li Zhaohong , Li Ye , Wu Zefeng , Yang Ruolin 
Published: February 2020

Abstract
In eukaryotes, the three-dimensional (3D) conformation of the genome is far from random, and this nonrandom chromatin organization is strongly correlated with gene expression and protein function, which are two critical determinants of the selective constraints and evolutionary rates of genes. However, whether genes and other elements that are located close to each other in the 3D genome evolve in a coordinated way has not been investigated in any organism. To address this question, we constructed chromatin interaction networks (CINs) in Arabidopsis thaliana based on high-throughput chromosome conformation capture data and demonstrated that adjacent large DNA fragments in the CIN indeed exhibit more similar levels of polymorphism and evolutionary rates than random fragment pairs. Using simulations that account for the linear distance between fragments, we proved that the 3D chromosomal organization plays a role in the observed correlated evolution. Spatially interacting fragments also exhibit more similar mutation rates and functional constraints in both coding and noncoding regions than the random expectations, indicating that the correlated evolution between 3D neighbors is a result of combined evolutionary forces. A collection of 39 genomic and epigenomic features can explain much of the variance in genetic diversity and evolutionary rates across the genome. Moreover, features that have a greater effect on the evolution of regional sequences tend to show higher similarity between neighboring fragments in the CIN, suggesting a pivotal role of epigenetic modifications and chromatin organization in determining the correlated evolution of large DNA fragments in the 3D genome.
What Is Community Policing?: Divergent Agendas, Practices, and Experiences of Transforming the Police in Kenya
Authors: Diphoorn Tessa , van Stapele Naomi 
Published: February 2020

AbstractIn line with global trends, community policing has been a vehicle for transforming the state police in Kenya. This article analyses various community policing efforts in Kenya and argues that many of these initiatives have largely failed to act as a vehicle for transformation due to three interconnected problems of diversity, representation, and ownership. The first problem—diversity—relates to the multiplicity of definitions, manifestations, and practices of community policing, which creates uncertainty and provides space for various actors to engage with it in conflicting ways. The second problem—representation—concerns the identification and creation of the ‘community’: this remains to occur in a state-driven manner and is also not a straightforward concept or organizational unit, especially in a highly multi-ethnic and classed setting as Kenya. The third is ownership: community policing is not experienced or exercised as a partnership, but as a state-centric framework that should remain under the direction and ownership of the state police. We make our claim by focusing on Likoni, Mombasa and drawing from further qualitative data conducted by both authors in Kenya.
Transmission and epidemiological characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infected Pneumonia (COVID-19): preliminary evidence obtained in comparison with 2003-SARS
Authors: Zhang Rongqiang , Liu Hui , Li Fengying , Zhang Bei , Liu Qiling , Li Xiangwen , Luo Limei 
Published: February 2020

AbstractObjectivesLatest epidemic data of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infected Pneumonia (COVID-19) was collected and a detailed statistical analysis was carried out to make comparison with 2003-SARS in order to provide scientific reference for the prevention and control of COVID-19.MethodsThe information of COVID-19 and 2003-SARS from websites of NHCPRC and the World Health Organization was collected, and then the transmission dynamics of the two kinds of infectious diseases were analyzed. The information of 853 confirmed COVID-19 patients obtained from the website of health committees of 18 provinces. A descriptive epidemiological analysis method was employed to carefully analyze the epidemic characteristics. Subsequently, the COVID-19 epidemic data in Wuhan and other inland regions of China was analyzed separately and compared. A multivariate function model was constructed based on the confirmed COVID-19 case data.ResultsThe growth rate of new cases and deaths of COVID-19 were significantly faster than those of 2003-SARS. The number of confirmed cases in Wuhan and other inland areas both showed increasing trends. 853 confirmed COVID-19 cases aged 1 months to 94 years and the average age was (45.05 ± 17.22) years. The gender ratio (M: F) was 1.12: 1.ConclusionsThe fatality rate of COVID-19 is lower than that of 2003-SARS and the cure rate is higher. The age of COVID-19 patients is mainly concentrated in the 30-50 years old (60.61%). The harm of the first-generation COVID-19 patients is higher than that of secondary cases.
Mapping metabolic oscillations during cell cycle progression
Authors: Roci Irena , Watrous Jeramie D. , Lagerborg Kim A. , Jain Mohit , Nilsson Roland 
Published: February 2020

AbstractProliferating cells must synthesize a wide variety of macromolecules while progressing through the cell cycle, but the coordination between cell cycle progression and cellular metabolism is still poorly understood. To identify metabolic processes that oscillate over the cell cycle, we performed comprehensive, non-targeted liquid chromatography-high resolution mass spectrometry (LC-HRMS) based metabolomics of HeLa cells isolated in the G1and SG2M cell cycle phases, capturing thousands of diverse metabolite ions. When accounting for increased total metabolite abundance due to cell growth throughout the cell cycle, 18% of the observed LC-HRMS peaks were at least 2-fold different between the stages, consistent with broad metabolic remodeling throughout the cell cycle. While most amino acids, phospholipids, and total ribonucleotides were constant across cell cycle phases, consistent with the view that total macromolecule synthesis does not vary across the cell cycle, certain metabolites were oscillating. For example, ribonucleotides were highly phosphorylated in SG2M, indicating an increase in energy charge, and several phosphatidylinositols were more abundant in G1, possibly indicating altered membrane lipid signaling. Within carbohydrate metabolism, pentose phosphates and methylglyoxal metabolites were associated with the cycle. Interestingly, hundreds of yet uncharacterized metabolites similarly oscillated between cell cycle phases, suggesting previously unknown metabolic activities that may be synchronized with cell cycle progression, providing an important resource for future studies.
High contiguityde novogenome sequence assembly of Trifoliate yam (Dioscorea dumetorum) using long read sequencing
Authors: Siadjeu Christian , Pucker Boas , Viehöver Prisca , Albach Dirk C. , Weisshaar Bernd 
Published: February 2020

AbstractTrifoliate yam (Dioscorea dumetorum) is one example of an orphan crop, not traded internationally. Post-harvest hardening of the tubers of this species starts within 24 hours after harvesting and renders the tubers inedible. Genomic resources are required forD. dumetorumto improve breeding for non-hardening varieties as well as for other traits. We sequenced theD. dumetorumgenome and generated the corresponding annotation. The two haplophases of this highly heterozygous genome were separated to a large extent. The assembly represents 485 Mbp of the genome with an N50 of over 3.2 Mbp. A total of 35,269 protein-encoding gene models as well as 9,941 non-coding RNA genes were predicted and functional annotations were assigned.
Earlier and More Robust Sensorimotor Discrimination of ASL Signs in Deaf Signers During Imitation
Authors: Quandt Lorna C. , Willis A. S. 
Published: February 2020

AbstractBackground:Prior research suggests that the amount of experience an individual has with an action influences the degree to which the sensorimotor systems of their brain are involved in the subsequent perception of those actions. Less is known about how action experience and conceptual understanding impact sensorimotor involvement during imitation. We sought to explore this question by comparing a group of sign language users to a group of non-signers. We pitted the following two hypotheses against each other: 1) Deaf signers will show increased sensorimotor activity during sign imitation, and greater differentiation between sign types, due to greater prior experience and conceptual understanding of the signs; versus 2): Deaf signers will show less sensorimotor system activity and less differentiation of sign types in the sensorimotor system, because for those individuals sign imitation involves language systems of the brain more robustly than sensorimotor systems. We collected electroencephalograms (EEG) while the two groups imitated videos showing one-handed and two-handed ASL signs. Time-frequency data analysis was performed on alpha- and beta-range oscillations while they watched signs with the intent to imitate, and imitated the signs. During observation, deaf signers showed early differentiation in alpha/beta power between the one- and two-handed sign conditions, whereas hearing non-signers did not discriminate between the sign categories this way. Significant differences between groups were seen during sign imitation, wherein deaf signers showed desynchronization of alpha/beta EEG signals, and hearing non-signers showed increased power. The study suggests that in an imitative context, deaf signers engage anticipatory motor preparation in advance of action production, while hearing non-signers engage slower, more memory-related processes to help them complete with the complex task.
Identifying Longevity Associated Genes by Integrating Gene Expression and Curated Annotations
Authors: Townes F. William , Carr Kareem , Miller Jeffrey W. 
Published: February 2020

SummaryAging is a complex process with poorly understood genetic mechanisms. Recent studies have sought to classify genes as pro-longevity or anti-longevity using a variety of machine learning algorithms. However, it is not clear which types of features are best for optimizing classification performance and which algorithms are best suited to this task. Further, performance assessments based on held-out test data are lacking. We systematically compare five popular classification algorithms using gene ontology and gene expression datasets as features to predict the pro-longevity versus anti-longevity status of genes for two model organisms (C. elegansandS. cerevisiae) using the GenAge database as ground truth. We find that elastic net penalized logistic regression performs particularly well at this task. Using elastic net, we make novel predictions of pro- and anti-longevity genes that are not currently in the GenAge database.
talklr uncovers ligand-receptor mediated intercellular crosstalk
Authors: Wang Yuliang 
Published: February 2020

AbstractSingle cell RNA-seq measures the transcriptomes of many cell types across diverse conditions. However, an emerging challenge is to uncover how different cell types communicate with each other to maintain tissue homeostasis, and how inter-cellular communications are perturbed in diseases. To address this problem, we developed talklr, an information theory-based approach to uncover potential ligand-receptor interactions involved in tissue homeostasis and diseases. Compared to existing approaches that analyze changes in each gene in each cell type separately, talklr uses a holistic approach to simultaneously consider expression changes in both ligands and receptors across multiple cell types and conditions. talklr outperformed existing approaches in identifying ligand-receptor interactions, including those known to be important for tissue-specific functions and diseases across diverse datasets. talklr can reveal important signaling events in many biological problems in an unbiased way, and will be a valuable tool in single cell RNA-seq analysis. talklr is available as both an interactive website and an R package.
Por uma rede que atravesse os tempos e que dê à produção lésbica a noção de continuidade
Authors: Santos Claudiana Gois dos , Barroso Carolina Hartfiel 
Published: February 2020

Natalia Borges Polesso é uma das escritoras de maior destaque nacional nos últimos anos. Após a grande repercussão de seu livro de contos Amora (2015), premiado em primeiro lugar na categoria contos e crônicas no Prêmio Jabuti (2016) e levando os prêmios Escolha do Leitor (Jabuti) e melhor narrativa curta pela Associação Gaúcha de Escritores do mesmo ano, Amora segue a trajetória iniciada pelo livro anterior de Natalia, Recortes para álbum de fotografias sem gente , publicado em 2013 e ganhador do Prêmio Açorianos do mesmo ano. A escritora também integra a lista Bogotá 39-2017, uma reunião dos 39 melhores escritores de ficção da América Latina com menos de 40 anos, e teve sua obra traduzida para o espanhol e o inglês em diversos países.
Essa premiada trajetória aumenta a visibilidade para suas narrativas e personagens majoritariamente lésbicas. Na entrevista que veremos a seguir, a escritora e pesquisadora de pós-doutorado na Universidade de Caxias do Sul, nos fala um pouco sobre as convergências entre sua pesquisa e sua escrita, o que se pode entender como “literatura lésbica”, tendo em vista o texto publicado no Dossiê Sáfico N 20 da revista Criação e Crítica, “Geografias lésbicas: literatura e gênero”. Aqui, buscamos entender o que a escritora e pesquisadora Natalia Polesso entende por “literatura lésbica”, como a discute, como entende a geografia como instrumento para análise literária, e como pensa a crítica literária lésbica.