bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence and fate of device‐related left pulmonary artery stenosis and aortic coarctation in small infants undergoing transcatheter patent ductus arteriosus closure
Authors: Tomasulo Catherine E. , Gillespie Matthew J. , Munson David , Demkin Taylor , O'Byrne Michael L. , Dori Yoav , Smith Christopher L. , Rome Jonathan J. , Glatz Andrew C. 
Published: April 2020

AbstractObjectivesTo evaluate short‐ and middle‐term outcomes after transcatheter patent ductus arteriosus (TC‐PDA) closure in small infants, specifically device‐related left pulmonary artery (LPA) stenosis and aortic coarctation, risk factors, and changes over time.BackgroundRecent studies have demonstrated successful transcatheter PDA (TC‐PDA) closure in small infants. LPA stenosis and aortic coarctation have been seen after TC‐PDA, but it is not clear whether device‐related LPA/aortic obstruction persists.MethodsA single‐center retrospective study of infants ≤4 kg who underwent TC‐PDA closure from February 1, 2007 to September 1, 2018 was performed, evaluating the incidence and risk factors for LPA stenosis and coarctation.ResultsForty‐four patients underwent successful TC‐PDA with Amplatzer Vascular Plug II (AVPII; n = 30), Amplatzer Duct Occluder II‐Additional Sizes (n = 10), Amplatzer Duct Occluder I (n = 3), and coil‐filled AVPI (n = 1) devices, all via an antegrade approach. Median birthweight and procedural weight were 890 g (range: 490–3,250) and 2.8 kg (range: 1.2–4.0), respectively. Median follow‐up was 0.7 years (range: 2 days–7 years). Thirty‐eight patients had post‐procedure echocardiograms assessing LPA/aortic obstruction. Of those, 17 had LPA flow acceleration/stenosis (≥1.5 m/s), which improved or resolved in all patients with available follow‐up; 3 developed mild coarctation (>2 m/s), which improved in the two with more than short‐term follow‐up; 4 developed mild flow acceleration (1.5–2 m/s) in the descending aorta, which resolved in three and increased in one (2.4 m/s). Flow acceleration in the LPA was associated with younger procedural age, larger PDA minimal diameter, and placement of a device other than the AVPII. There was no device‐related mortality or need for reintervention.ConclusionTC‐PDA in small infants is effective, without significant complications. Device‐related LPA/aortic obstruction can improve with time/growth.
Phosphorus‐Modified Mesoporous Inorganic Materials for Production of Hydrocarbon Fuels and Value‐Added Chemicals
Authors: Kasipandi Saravanan , Ali Mansoor , Li Yongdan , Bae Jong Wook 
Published: April 2020

AbstractPhosphorus‐modified mesoporous inorganic materials play crucial roles in the valorization of lignocellulosic biomass materials such as syngas (CO and H2), carbohydrate sugars and lignin. This review summarizes the recent advances on the Co‐impregnated phosphorus‐modified γ‐Al2O3 and SiO2 catalysts for production of liquid hydrocarbon fuels via Fischer‐Tropsch synthesis (FTS) reaction of syngas as well as metal phosphates or precious (Pt and Ru) metals‐supported on the metal phosphates for production of furanic compounds, levulinic acid, aromatics and fuel commodities from carbohydrate sugars and lignin. These phosphorus‐modified materials play key roles in the syngas as well as biomass conversion processes due to their tunable surface properties and mesoporous structures. Phosphorus to metal ratios of inorganic materials with their porosity, calcination temperatures of metal phosphates, natures of biomass feedstocks, and reaction variables significantly affect yields of both hydrocarbon fuels and value‐added chemicals. This short review mainly focusses on the various applications of those mesoporous catalysts and supports, and strategies for effective catalytic transformations of lignocellulosic biomass‐derived feedstocks.
Progress on Selective Catalytic Ammonia Oxidation (NH3‐SCO) over Cu−Containing Zeolite‐Based Catalysts
Authors: Jabłońska Magdalena 
Published: April 2020

AbstractThe selective catalytic oxidation of ammonia into nitrogen and water vapor (NH3‐SCO) has proven to be the most efficient technique for the removal of NH3 from the oxygen‐containing diesel exhausts. Until now, two reviews over investigated catalysts have been published in 2015–2016 (Jabłońska et al., RCS. Adv. 2015; Appl. Catal. B: Environ. 2016). Among various NH3‐SCO catalysts, Cu‐ and/or Fe‐containing zeolites are considered as promising candidates due to their benign nature, NH3 storage capacity, very high NH3 conversion and N2 selectivity. The present review focusses only on the Cu‐containing zeolites (mainly on chabazite (CHA): SSZ‐13, SAPO‐34) catalysts) applied in NH3‐SCO starting from 2015. The synthesis/preparation methods and the state of Cu in catalysts on the activity and selectivity are highlighted. The advantages of the understanding of the reaction mechanism are reviewed. Finally, an outlook is given together with expected inspirations for future research directions in developing zeolite‐based catalysts.
Dendrite‐Free Lithium Anodes with a Metal Organic Framework‐Derived Cake‐like TiO2 Coating on the Separator
Authors: Fu Shiyang , Wang Lili , Zhao Teng , Li Li , Wu Feng , Chen Renjie 
Published: April 2020

AbstractLithium metal, with a high theoretical capacity of 3860 mAh/g and a low electrochemical potential of −3.040 V, is an attractive anode material. However, its application has been hampered by irregular lithium dendrite growth and low coulombic efficiency. To solve these problems, a facile air calcination strategy was used to prepare cake‐like TiO2 nanoparticles with rich pores, which were further coated on one side of the commercial Celgard separator. The nanoscale mesoporous channels on the surface of TiO2 particles can effectively block the growth of lithium dendrites, leading to dense and uniform Li deposition with a high coulombic efficiency. Compared with the blank cell (50 cycles of normal operation), the Li||Cu cell with modified separator can run 100 cycles at 2 mA/cm2 with an average coulombic efficiency of 97.3 %. These results herald a new approach to dendrite‐free lithium anodes by nanostructured ceramic coating on the separator.
Ultrathin NiFeS Nanomeshes with Sulfur Vacancy for Electrocatalytic Hydrogen Evolution
Authors: Ma Aijing , Wang Changhong , Lu Yao , Wu Xuan , Mamba Bhekie B. , Kuvarega Alex T. , Kefeni Kebede K. , Gui Jianzhou , Liu Dan 
Published: April 2020

AbstractThe development of novel transition metal‐based electrocatalysts with high hydrogen evolution reaction (HER) activity is significant. NiFeS shows promising potential for HER because of its suitable electronic configuration. However, the low ratio of accessible active sites hinders its HER performance. Processing NiFeS into ultrathin nanosheets with abundant pores and vacancies can increase the number of active sites and enhance the intrinsic activity of active sites, but, the synthesis is still challenging. Here, we developed a facile two‐step conversion strategy to prepare ultrathin NiFeS nanomeshes with sulfur vacancies (NiFeS1‐x UNM). The overpotential of NiFeS1‐x UNM for 10 mA cm−2 was only 81 mV in acid electrolyte, much lower than the counterpart of NiFeS nanosheets (NiFeS NS) without sulfur vacancies (118 mV). Combining the electrochemical characterizations and Density Functional Theory (DFT) calculations, we revealed that the superior performance of NiFeS1‐x UNM originated from the increased active sites, accelerated electron/mass transfer and improved intrinsic activity.
Rottlerin: Structure Modifications and KCNQ1/KCNE1 Ion Channel Activity
Authors: Lübke Marco , Schreiber Julian A. , Le Quoc Thang , Körber Florian , Müller Jasmin , Sivanathan Sivatharushan , Matschke Veronika , Schubert Janina , Strutz‐Seebohm Nathalie , Seebohm Guiscard , Scherkenbeck Jürgen 
Published: April 2020

AbstractThe slow delayed rectifier potassium current (IKs) is formed by the KCNQ1 (Kv7.1) channel, an ion channel of four α‐subunits that modulates KCNE1 β‐subunits. IKs is central to the repolarization of the cardiac action potential. Loss of function mutation reducing ventricular cardiac IKs cause the long‐QT syndrome (LQTS), a disorder that predisposes patients to arrhythmia and sudden death. Current therapy for LQTS is inadequate. Rottlerin, a natural product of the kamala tree, activates IKs and has the potential to provide a new strategy for rational drug therapy. In this study, we show that simple modifications such as penta‐acetylation or penta‐methylation of rottlerin blunts activation activity. Total synthesis was used to prepare side‐chain‐modified derivatives that slowed down KCNQ1/KCNE1 channel deactivation to different degrees. A binding hypothesis of rottlerin is provided that opens the way to improved IKs activators as novel therapeutics for the treatment of LQTS.
Dopamine‐Modified Zero‐Valent Iron Nanoparticles for Dual‐Modality Photothermal and Photodynamic Breast Cancer Therapy
Authors: Yu Hsin Her , Lin Chia‐Hua , Chen Yi‐Chun , Chen Hung‐Hsiang , Lin Yu‐Jing , Lin Kun‐Yi Andrew 
Published: April 2020

AbstractPhototherapy has the advantages of minimal invasion, few side effects, and improved accuracy for cancer therapy. The application of a polydopamine (PDA)‐modified nano zero‐valent iron (nZVI@PDA) as a new synergistic agent in combination with photodynamic/photothermal (PD/PT) therapy to kill cancer cells is discussed here. The nZVI@PDA offered high light‐to‐heat conversion and ROS generation efficiency under near‐infrared (NIR) irradiation (808 nm), thus leading to irreversible damage to nZVI@PDA‐treated MCF‐7 cells at low concentration, without inducing apoptosis in normal cells. Irradiation of nZVI@PDA using an NIR laser converted the energy of the photons to heat and ROS. Our results showed that modification of the PDA on the surface of nZVI can improve the biocompatibility of the nZVI@PDA. This work integrated the PD and PT effects into a single nanodevice to afford a highly efficient cancer treatment. Meanwhile, nZVI@PDA, which combines the advantages of PDA and nZVI, displayed excellent biocompatibility and tumoricidal ability, thus suggesting its huge potential for future clinical research in cancer therapy.
Structure‐Activity Relationships of Butyrophilin 3 Ligands
Authors: Wiemer Andrew J. 
Published: April 2020

AbstractPhosphoantigens (pAgs) are small phosphorus‐containing molecules that stimulate Vγ9Vδ2 T cells with sub‐nanomolar cellular potency. Recent work has revealed that these compounds work through binding to the transmembrane immunoglobulin butyrophilin 3A1 (BTN3A1) within its intracellular B30.2 domain. Engagement of BTN3A1 is critical to the formation of an immune synapse between cells that contain pAgs and the Vγ9Vδ2 T cells. This minireview summarizes the structure‐activity relationships of pAgs and their implications to the mechanisms of butyrophilin 3 activation leading to Vγ9Vδ2 T cell response.
Thermo‐Photocatalytic Methanol Reforming for Hydrogen Production over a CuPd−TiO2 Catalyst
Authors: López‐Martín A. , Platero F. , Caballero A. , Colón Gerardo 
Published: April 2020

AbstractA bimetallic CuPd/TiO2 system has been prepared by a two‐step synthesis and was used for a methanol steam photoreforming reaction. By sequential deposition, palladium is deposited over copper nanoclusters through a galvanic replacement process. Hydrogen production by steam reforming from methanol was achieved by both thermo‐photocatalytic and photocatalytic processes. It appears that H2 production on the bimetallic system is notably higher than the Pd monometallic reference. Moreover this difference in the catalytic performance could be related to the higher CO evolution observed for the monometallic Pd1.0 TiO2 system which is partially inhibited in the bimetallic catalyst. In addition, an important thermal effect can be envisaged in all cases. Nevertheless, this improved effect in the thermo‐photocatalytic process is accompanied by a remarkable CO evolution and SMSI effect (important strong metal‐support interactions) that hindered the efficiency as temperature increases. On this basis, optimal operational conditions for H2 production are obtained for thermo‐photocatalytic reforming at 100 °C, for which the synergetic effect is higher with lower CO production (H2/CO=4).
Myo‐inositol enhances drought tolerance in creeping bentgrass through alteration of osmotic adjustment, photosynthesis, and antioxidant defense
Authors: Li Zhou , Fu Jingyan , Shi Diwen , Peng Yan 
Published: April 2020

AbstractMyo‐inositol (MI) regulates stress adaptation in plants. The objective of this study was to investigate effects of foliar MI application on improving drought tolerance associated with osmotic adjustment (OA), photosynthesis, and antioxidant defense in creeping bentgrass (Agrostis stolonifera L.). Both MI‐pretreated (1 mM) and untreated plants were subjected to drought stress or well‐watered conditions for 12 d in growth chambers. Results showed that exogenous MI application protected plants from drought damage by improving OA and water use efficiency, and this contributed to better water status in creeping bentgrass. Interestingly, the foliar spray of MI promoted the accumulation of water‐soluble carbohydrates but decreased drought‐induced free proline in leaves. The MI‐pretreated plants exhibited significantly greater chlorophyll (Chl) content, photochemical efficiency (Fv/Fm), performance index on an absorption basis (PIABS), and net photosynthetic rate (Pn) than untreated plants in response to drought stress. Foliar application of MI decreased superoxide anion radical, H2O2, and malondialdehyde contents and electrolyte leakage but increased superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), and ascorbate peroxidase (APX) activities and gene expression in leaves under drought stress. This study indicates that MI‐induced drought tolerance was involved in the maintenance of better water relation associated with increases in OA and water use efficiency, the decline in Chl loss for photosynthetic maintenance, and improvement in antioxidant enzymes activity and gene expression contributing to less oxidative damage under drought stress. It is worth further investigating stress‐defensive proteins and metabolites induced by MI in turfgrass or other plant species under drought stress or other abiotic stresses.
Light‐Intensity‐Responsive Changes of Products in Photocatalytic Reduction of Nitrous Acid on a Cu‐Doped Covalent Triazine Framework–TiO2 Hybrid
Authors: Kamiya Kazuhide , Sugimoto Rino , Tatebe Tomomi , Harada Takashi , Nakanishi Shuji 
Published: April 2020

AbstractIn the design of solar‐energy conversion electrochemical systems, it is important to consider that natural sunlight fluctuates. By taking nitrous acid photoreduction as an example, this study has shown that the reaction pathway, and hence the reaction products, dynamically respond to variations in light intensity. Under irradiation, the photooxidation of methanol (as sacrificial agent) on TiO2 and the reduction of HNO2 on a Cu‐modified covalent triazine framework (Cu‐CTF) are electrically coupled, which leads to the photoreduction of HNO2 without an external bias. The major product of the reaction changes from N2O to NH4+ with an increase in the light intensity. The operating potential also shifts negatively (or positively) when the light intensity is increased (or decreased). These results indicate that a change in the reaction pathway is triggered by a change in the operating potential of the Cu‐CTF catalyst under varying light intensity. Such a light‐intensity‐dependent change in the reaction pathway is particularly important in systems that use photoresponsive electrodes and where multiple products can be obtained, such as the solar‐driven reduction of carbon dioxide and nitrogen oxides.
A new strain group of common carp: The genetic differences and admixture events between Cyprinus carpio breeds
Authors: Nedoluzhko Artem V. , Slobodova Natalia V. , Sharko Fedor , Shalgimbayeva Gulmira M. , Tsygankova Svetlana V. , Boulygina Eugenia S. , Jeney Zsigmond , Nguyen Van Q. , Pham Thế T. , Nguyen Đức T. , Volkov Alexander A. , Fernandes Jorge M.O. , Rastorguev Sergey M. 
Published: April 2020

AbstractCommon carp (Cyprinus carpio) has an outstanding economic importance in freshwater aquaculture due to its high adaptive capacity to both food and environment. In fact, it is the third most farmed fish species worldwide according to the Food and Agriculture Organization. More than four million tons of common carp are produced annually in aquaculture, and more than a hundred thousand tons are caught from the wild. Historically, the common carp was also the first fish species to be domesticated in ancient China, and now, there is a huge variety of domestic carp strains worldwide. In the present study, we used double digestion restriction site‐associated DNA sequencing to genotype several European common carp strains and showed that they are divided into two distinct groups. One of them includes central European common carp strains as well as Ponto–Caspian wild common carp populations, whereas the other group contains several common carp strains that originated in the Soviet Union, mostly as cold‐resistant strains. We believe that breeding with wild Amur carp and subsequent selection of the hybrids for resistance to adverse environmental conditions was the attribute of the second group. We assessed the contribution of wild Amur carp inheritance to the common carp strains and discovered discriminating genes, which differed in allele frequencies between groups. Taken together, our results improve our current understanding of the genetic variability of common carp, namely the structure of natural and artificial carp populations, and the contribution of wild carp traits to domestic strains.
Chaos‐based privacy preserving vehicle safety protocol for 5G Connected Autonomous Vehicle networks
Authors: Ansari Shuja , Ahmad Jawad , Aziz Shah Syed , Kashif Bashir Ali , Boutaleb Tuleen , Sinanovic Sinan 
Published: April 2020

AbstractThere is a high demand for secure and reliable communications for Connected Autonomous Vehicles (CAVs) in the automotive industry. Privacy and security are key issues in CAVs, where network attacks can result in fatal accidents. The computational time, cost, and robustness of encryption algorithms are important factors in low latency 5G‐enabled secure CAV networks. The presented chaotic Tangent‐Delay Ellipse Reflecting Cavity‐Map system and PieceWise Linear Chaotic Map‐based encryption on short messages exchanged in a CAV network provide both robustness and high speed encryption. In this work, we propose a 5G radio network architecture, which leverages multiple radio access technologies and utilizes Cloud Radio Access Network functionalities for privacy preserved and secure CAV networks. The proposed Vehicular Safety Message identifier algorithm meets transmission requirements with a high probability of 85% for low round trip delay of ≤50 milliseconds. The proposed chaos‐based encryption algorithm exhibits faster speeds with a computational time of 2 to 3 milliseconds, showcasing its lightweight properties ideal for time critical applications.
Modified ghost fluid method for three‐dimensional compressible multimaterial flows with interfaces exhibiting large curvature and topological change
Authors: Xu Liang , Liu Tiegang 
Published: April 2020

SummaryIn order to capture the material interface dynamics, especially under the impact of strong shocks, the key feature of the modified ghost fluid method (MGFM) is to construct a multimaterial Riemann problem normal to the interface and use its solution to define interface conditions. However, such process sometimes may not be easily or accurately implemented when the multidimensional interfaces come into contact or undergo significant deformations. In this article, a three‐dimensional interface treating procedure is developed for a wide range of compressible multimaterial flows. It utilizes the MGFM with an explicit approximate Riemann problem solver to define interface conditions. More importantly, a weighted average technique is designed to optimize the treatment for interfaces exhibiting large curvature and topological change. This remedies two defects of the traditional approach in these extreme cases. One is that the normal directions of interfacial ghost nodes may not be easily calculated. The other is that the interface conditions may not be accurately defined. The numerical methodology is validated through several typical problems, including gas‐liquid Riemann problem and shock‐bubble/droplet interaction. These results indicate that the developed method is capable of dealing with interfacial evolutions in three dimensions, especially when interfaces undergo merger, fragmentation, and other complex changes.
An evaluation of the effectiveness of dental health training administered at a health services school
Authors: Kılınç Gülser , Açıkgöz Ayla , Koca Bennur , Toyran Neslihan , Güldaş Nevcivan 
Published: April 2020

AbstractIssue addressedThe aim of this study was to determine the knowledge and behaviour of health technician students to determine their oral health (OH) status, and to evaluate the effectiveness of a structured education administered for increasing OH awareness.MethodsInterventional research was performed between December 2018 and March 2019 on 445 Vocational School of Health Services students in … University. Questionnaires were conducted under observation. The first questionnaire (Q1) included socio‐demographic characteristics, OH knowledge level, attitudes and behaviours. One month after the OH training was given to the students, the same questions in Q1 were asked again in the second questionnaire (Q2). Dental caries and Simplified Oral Hygiene Index (OHI‐S) status were determined by a dentist via a clinical oral examination.ResultsOf the 445 students, 416 (93.5%) participated in the study and completed the Q1 and Q2 questionnaires. A total of 277 (66.6%) students were female and 139 (33.4%) were male, with the age range being 17‐33 years (average: 19.2 ± 1.86 years). Of the 416 students who answered the Q1 and Q2 questionnaires, 385 received oral examinations. While the Q1 knowledge score was 7.06 ± 2.08, the Q2 was found to be 12.36 ± 2.90 (P < .001). It was seen that 119 (30.9%) students who had poor OHI‐S and 120 (31.2%), had a mean number of decayed, missing and filled teeth (DMFT) value of 6 and above. It was found that the females had better OH values ​​than males (P < .001) and smokers had worse OH values overall (P < .016).ConclusionIt was observed that the health technician students had a low level of knowledge about OH before the training but after receiving the training, their knowledge, attitude and behaviour changed positively.So what?It was concluded that the OH education given to students caused a positive change in their behaviour, attitude and knowledge.
Front Cover: Stereotaxic endoscopy for the ocular imaging of awake, freely moving animal models (J. Biophotonics 5/2020)
Authors: Paulson Bjorn , Lee Sangwook , Jue Miyeon , Lee Kyungsung , Lee Sanghwa , Kim Guk Bae , Moon Youngjin , Lee Joo Yong , Kim Namkug , Kim Jun Ki 
Published: April 2020

AbstractA 3D printed stereotaxic head mount that enables high resolution imaging of the anterior chamber of the eye in alert and freely mobile mice is designed in this study. The system is placed non‐invasively using temporal mount bars and a snout mount, without breaking the skin or risking suffocation, while an endoscopic channel stabilizes the ocular probes.Further details can be found in the article by Bjorn Paulson, Sangwook Lee, Miyeon Jue, Kyungsung Lee, Sanghwa Lee, Guk Bae Kim, Youngjin Moon, Joo Yong Lee, Namkug Kim, and Jun Ki Kim (e201960188).
image