bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Quarterly Performance in Science of Grade 7 Students in Public School
Authors: Francisco Leonardo M. Jr. , Ongoco Areeya Amor 
Published: May 2020

In a typical science curriculum with different scientific disciplines (Chemistry, Biology, Physics and Earth Sciences) taught in every quarter, it is important to determine the difference in the performance of students under each discipline. In this study, the comparison of quarterly performance in Science of Grade 7 Students was examined. Wherein, the consolidated quarterly grades in science from the previous school year (June 2018 - April 2019) from five sections with a total of 272 male and female grade 7 students were used as data. It employed a quantitative research design using a One-way Analysis of Variance ( ANOVA) to determine the significant difference in the mean grades per quarter. Additionally, an interview with the science teachers who handled the samples was conducted to gather qualitative data to further explain the results. The results of this study revealed a mean of 83.50 from the combined grades in the second quarter which is the lowest among the four quarters. However, the results from ANOVA generated a significance of .123 (p≥.05) which means that there is no significant difference between the grades in the first, second, third and fourth quarter.
Temporopolar amygdalohippocampectomy: seizure control and postoperative outcomes
Authors: de Souza João Paulo Sant Ana Santos , Ayub Gabriel , Nogueira Mateus , Zanao Tamires , Lopes Tátila Martins , Pimentel-Silva Luciana Ramalho , Domene Vinicius , Marquez Gabriel , Yasuda Clarissa Lin , Ribeiro Letícia Franceschet , Campos Brunno M. , Vasconcellos José , Rogerio Fabio , Joaquim Andrei Fernandes , Cendes Fernando , Tedeschi Helder , Ghizoni Enrico 
Published: May 2020

OBJECTIVE
The objective of this study was to evaluate the efficacy and safety of a modified surgical approach for the treatment of temporal lobe epilepsy secondary to hippocampal sclerosis (HS). This modified approach, called temporopolar amygdalohippocampectomy (TP-AH), includes a transsylvian resection of the temporal pole and subsequent amygdalohippocampectomy utilizing the limen insula as an anatomical landmark.

METHODS
A total of 61 patients who were diagnosed with HS and underwent TP-AH between 2013 and 2017 were enrolled. Patients performed pre- and postoperative diffusion tensor imaging and were classified according to Engel’s scale for seizure control. To evaluate the functional preservation of the temporal stem white-matter fiber tracts, the authors analyzed postoperative Humphrey perimetries and pre- and postoperative neurocognitive performance (Rey Auditory Verbal Learning Test [RAVLT], Weschler Memory Scale–Revised [WMS-R], intelligence quotient [IQ], Boston Naming Test [BNT], and semantic and phonemic fluency). Demographic data and surgical complications were also recorded and described.

RESULTS
After a median follow-up of 36 ± 16 months, 46 patients (75.4%) achieved Engel class I, of whom 37 (60.6%) were Engel class IA. No significant changes in either the inferior frontooccipital fasciculus and optic radiation tractography were observed postoperatively for both left- and right-side surgeries. Reliable perimetry was obtained in 40 patients (65.6%), of whom 27 (67.5%) did not present any visual field defects (VFDs) attributable to surgery, while 12 patients (30%) presented with quadrant VFD, and 1 patient (2.5%) presented with hemifield VFD. Despite a significant decline in verbal memory (p = 0.007 for WMS-R, p = 0.02 for RAVLT recognition), there were significant improvements in both IQ (p < 0.001) and visual memory (p = 0.007). Semantic and phonemic fluency, and scores on the BNT, did not change postoperatively.

CONCLUSIONS
TP-AH provided seizure control similar to historical temporal lobe approaches, with a tendency to preserve the temporal stem and a satisfactory incidence of VFD. Despite a significant decline in verbal memory, there were significant improvements in both IQ and visual memory, along with preservation of executive function. This approach can be considered a natural evolution of the selective transsylvian approach.
Preoperative localization of seizure onset zones by magnetic source imaging, EEG-correlated functional MRI, and their combination
Authors: Berger Assaf , Cohen Noa , Fahoum Firas , Medvedovsky Mordekhay , Meller Aaron , Ekstein Dana , Benifla Mony , Aizenstein Orna , Fried Itzhak , Gazit Tomer , Strauss Ido 
Published: May 2020

OBJECTIVE
Preoperative localization of seizure onset zones (SOZs) is an evolving field in the treatment of refractory epilepsy. Both magnetic source imaging (MSI), and the more recent EEG-correlated functional MRI (EEG-fMRI), have shown applicability in assisting surgical planning. The purpose of this study was to evaluate the capability of each method and their combination in localizing the seizure onset lobe (SL).

METHODS
The study included 14 patients who underwent both MSI and EEG-fMRI before undergoing implantation of intracranial EEG (icEEG) as part of the presurgical planning of the resection of an epileptogenic zone (EZ) during the years 2012–2018. The estimated location of the SL by each method was compared with the location determined by icEEG. Identification rates of the SL were compared between the different methods.

RESULTS
MSI and EEG-fMRI showed similar identification rates of SL locations in relation to icEEG results (88% ± 31% and 73% ± 42%, respectively; p = 0.281). The additive use of the coverage lobes of both methods correctly identified 100% of the SL, significantly higher than EEG-fMRI alone (p = 0.039) and nonsignificantly higher than MSI (p = 0.180). False-identification rates of the additive coverage lobes were significantly higher than MSI (p = 0.026) and EEG-fMRI (p = 0.027). The intersecting lobes of both methods showed the lowest false identification rate (13% ± 6%, p = 0.01).

CONCLUSIONS
Both MSI and EEG-fMRI can assist in the presurgical evaluation of patients with refractory epilepsy. The additive use of both tests confers a high identification rate in finding the SL. This combination can help in focusing implantation of icEEG electrodes targeting the SOZ.
A matched-pair analysis of clinical outcomes after intracavitary cesium-131 brachytherapy versus stereotactic radiosurgery for resected brain metastases
Authors: Julie Diana A. , Lazow Stefanie P. , Vanderbilt Daniel B. , Taube Shoshana , Yondorf Menachem Z. , Sabbas Albert , Pannullo Susan , Schwartz Theodore H. , Wernicke A. Gabriella 
Published: May 2020

OBJECTIVE
Adjuvant radiation therapy (RT), such as cesium-131 (Cs-131) brachytherapy or stereotactic radiosurgery (SRS), reduces local recurrence (LR) of brain metastases (BM). However, SRS is less efficacious for large cavities, and the delay between surgery and SRS may permit tumor repopulation. Cs-131 has demonstrated improved local control, with reduced radiation necrosis (RN) compared to SRS. This study represents the first comparison of outcomes between Cs-131 brachytherapy and SRS for resected BM.

METHODS
Patients with BM treated with Cs-131 and SRS following gross-total resection were retrospectively identified. Thirty patients who underwent Cs-131 brachytherapy were compared to 60 controls who received SRS. Controls were selected from a larger cohort to match the patients treated with Cs-131 in a 2:1 ratio according to tumor size, histology, performance status, and recursive partitioning analysis class. Overall survival (OS), LR, regional recurrence, distant recurrence (DR), and RN were compared.

RESULTS
With a median follow-up of 17.5 months for Cs-131–treated and 13.0 months for SRS-treated patients, the LR rate was significantly lower with brachytherapy; 10% for the Cs-131 cohort compared to 28.3% for SRS patients (OR 0.281, 95% CI 0.082–0.949; p = 0.049). Rates of regional recurrence, DR, and OS did not differ significantly between the two cohorts. Kaplan-Meier analysis with log-rank testing showed a significantly higher likelihood of freedom from LR (p = 0.027) as well as DR (p = 0.018) after Cs-131 compared to SRS treatment (p = 0.027), but no difference in likelihood of OS (p = 0.093). Six (10.0%) patients who underwent SRS experienced RN compared to 1 (3.3%) patient who received Cs-131 (p = 0.417).

CONCLUSIONS
Postresection patients with BM treated with Cs-131 brachytherapy were more likely to achieve local control compared to SRS-treated patients. This study provides preliminary evidence of the potential of Cs-131 to reduce LR following gross-total resection of single BM, with minimal toxicity, and suggests the need for a prospective study to address this question.
Long-term outcome of large sylvian arachnoid cysts: the role of surgery has been exaggerated
Authors: Kim Kyung Hyun , Lee Ji Yeoun , Phi Ji Hoon , Kim Seung-Ki , Cho Byung-Kyu , Wang Kyu-Chang 
Published: May 2020

OBJECTIVEThe surgical indications for some arachnoid cysts (ACs) are controversial. While surgical procedures can be effective when an AC is a definite cause of hydrocephalus or papilledema, most ACs do not cause any symptoms or signs. Some surgeons perform several procedures to treat ACs because of their large size. The purpose of this study was to compare the long-term outcomes of Galassi type III ACs between surgery and nonsurgery groups.METHODSThe medical records of 60 patients diagnosed with sylvian ACs (Galassi type III) who visited Seoul National University Children’s Hospital from July 1990 to March 2018 were analyzed. The authors compared the outcomes between those treated with surgery and those not treated with surgery.RESULTSOf the 60 patients, 27 patients had no symptoms, 19 patients had vague symptoms and signs associated with ACs, and the remaining 14 patients had definite AC-related symptoms and signs. Thirty-eight patients underwent surgery, and 22 patients underwent observation. Some operations were accompanied by complications. Among the 33 patients in the surgery group, excluding 5 with hydrocephalus or papilledema, 8 patients needed 18 additional operations. However, there were no patients in the nonsurgery group who needed surgical intervention during the follow-up period (mean 67.5 months), although the size of the AC increased in 2 patients. Changes in AC size were not correlated with symptom relief.CONCLUSIONSWhen patients with hydrocephalus or papilledema were excluded, there was no difference in the outcomes between the surgery and nonsurgery groups regardless of the size of the sylvian AC. Surgeons should be cautious when deciding whether to operate.
Radiographic findings for surgery-related complications after pedicle subtraction osteotomy for thoracolumbar kyphosis in 230 patients with ankylosing spondylitis
Authors: Lee Keun-Ho , Kim Ki-Tack , Kim Yong-Chan , Lee Joong-Won , Ha Kee-Yong 
Published: May 2020

OBJECTIVEThe purpose of this study was to investigate the rate of and the risk factors for surgery-related complications demonstrated on radiography after pedicle subtraction osteotomy (PSO) for thoracolumbar kyphosis in patients with ankylosing spondylitis (AS).METHODSThe authors retrospectively reviewed the medical records of 230 consecutive patients with thoracolumbar kyphosis due to AS who had undergone 1-level PSO at a single institution in the period from 2010 to 2017. The causes of surgery-related complications were divided into two types: surgical/technical failure and mechanical failure.RESULTSThe patients consisted of 20 women and 210 men, with an average age of 43.4 years. The average follow-up period was 39.0 months. The preoperative sagittal vertical axis was 18.5 ± 69.3 cm, which improved to 4.9 ± 4.6 cm after PSO. Of the 77 patients (33.5%) who experienced minor or major surgery-related complications, 56 had complications related to surgical/technical failure (overall incidence 24.3%) and 21 had complications related to mechanical failure (overall incidence 9.1%). Fourteen patients (6.1%) underwent reoperation. However, among the 77 patients with complications, the rate of revision surgery was 18.2%. The most common radiological complications were as follows: sagittal translation in 24 patients, coronal imbalance in 20, under-correction in 8, delayed union in 8, and distal junctional failure and kyphosis in 8. The most common causes of reoperation were coronal imbalance in 4 patients, symptomatic malposition of pedicle screws in 3, and distal junctional failure in 3. Delayed union was statistically correlated with posterior sagittal translation (p = 0.007).CONCLUSIONSPSO can provide acceptable radiographic outcomes for the correction of thoracolumbar kyphosis in patients with AS. However, a high incidence of surgery-related complications related to mechanical failure and surgical technique can develop. Thorough radiographic investigation before and during surgery is needed to determine whether complete ossification occurs along the anterior and posterior longitudinal ligaments of the spine.
BiGe-Onto: An ontology-based system for managing biodiversity and biogeography data1
Authors: Zárate Marcos , Braun Germán , Fillottrani Pablo , Delrieux Claudio , Lewis Mirtha 
Published: May 2020

Great progress to digitize the world’s available Biodiversity and Biogeography data have been made recently, but managing data from many different providers and research domains still remains a challenge. A review of the current landscape of metadata standards and ontologies in Biodiversity sciences suggests that existing standards, such as the Darwin Core terminology, are inadequate for describing Biodiversity data in a semantically meaningful and computationally useful way. As a contribution to fill this gap, we present an ontology-based system, called BiGe-Onto, designed to manage data together from Biodiversity and Biogeography. As data sources, we use two internationally recognized repositories: the Global Biodiversity Information Facility (GBIF) and the Ocean Biogeographic Information System (OBIS). BiGe-Onto system is composed of (i) BiGe-Onto Architecture (ii) a conceptual model called BiGe-Onto specified in OntoUML, (iii) an operational version of BiGe-Onto encoded in OWL 2, and (iv) an integrated dataset for its exploitation through a SPARQL endpoint. We will show use cases that allow researchers to answer questions that manage information from both domains.
Gene Ontology Curation of Neuroinflammation Biology Improves the Interpretation of Alzheimer’s Disease Gene Expression Data
Authors: Kramarz Barbara , Huntley Rachael P. , Rodríguez-López Milagros , Roncaglia Paola , Saverimuttu Shirin C.C. , Parkinson Helen , Bandopadhyay Rina , Martin Maria-Jesus , Orchard Sandra , Hooper Nigel M. , Brough David , Lovering Ruth C. 
Published: May 2020

Background: Gene Ontology (GO) is a major bioinformatic resource used for analysis of large biomedical datasets, for example from genome-wide association studies, applied universally across biological fields, including Alzheimer’s disease (AD) research. Objective: We aim to demonstrate the applicability of GO for interpretation of AD datasets to improve the understanding of the underlying molecular disease mechanisms, including the involvement of inflammatory pathways and dysregulated microRNAs (miRs). Methods: We have undertaken a systematic full article GO annotation approach focused on microglial proteins implicated in AD and the miRs regulating their expression. PANTHER was used for enrichment analysis of previously published AD data. Cytoscape was used for visualizing and analyzing miR-target interactions captured from published experimental evidence. Results: We contributed 3,084 new annotations for 494 entities, i.e., on average six new annotations per entity. This included a total of 1,352 annotations for 40 prioritized microglial proteins implicated in AD and 66 miRs regulating their expression, yielding an average of twelve annotations per prioritized entity. The updated GO resource was then used to re-analyze previously published data. The re-analysis showed novel processes associated with AD-related genes, not identified in the original study, such as ‘ gliogenesis’, ‘ regulation of neuron projection development’, or ‘ response to cytokine’, demonstrating enhanced applicability of GO for neuroscience research. Conclusions: This study highlights ongoing development of the neurobiological aspects of GO and demonstrates the value of biocuration activities in the area, thus helping to delineate the molecular bases of AD to aid the development of diagnostic tools and treatments.
Sol-gel Synthesis and Characterization of Lithium and Cerium Codoped Perovskite
Authors: Mužina Katarina , Tkalčević Marija , Brleković Filip , Munda Ivana Katarina , Mandić Vilko , Šipušić Juraj , Kurajica Stanislav 
Published: May 2020

Perovskites are an important group of ceramic materials with a structural formula ABO3 and wide array of potential applications in electronics, superconductors, catalysis, etc. CaTiO3, by which the whole group was named for, is particularly significant due to its use in catalysis, but its photocatalytic activity is limited by a large band gap value (~3.5 eV). A possible solution is the substitution of A and B cations with foreign cations which causes the alteration of properties, including photocatalytic efficiency. The aim of this work was the sol-gel synthesis of lithium and cerium codoped CaTiO3, characterization of the prepared gel and ceramics obtained by its thermal treatment. Samples of codoped perovskite, Ca1-xLixCexTiO3, where x = 0, 0.01, 0.02, 0.03 and 0.04, were prepared and characterized using powder X–ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), differential thermal and thermo-gravimetric analysis (DTA-TGA), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). Photocatalytic activity was evaluated through the study of methylene blue photocatalytic degradation. XRD analysis showed that the prepared samples consisted of calcium nitrate and titanium chelate. In accordance with the established thermal evolution path, all samples were thermally treated at 500 °C for 2 hours. Beside perovskite, Ca2Ti2O6 appeared as a secondary phase in all thermally treated samples. SEM analysis of thermally treated samples showed the presence of agglomerates of irregular morphology and the decrease of primary particles size with the increase of dopants concentration. The sample with x=0.04 showed an increased photocatalytic activity.
KARAKTERISTIK PERMUKIMAN DI TEPIAN SUNGAI
Authors: Sastika Anta , Yasir Abdul 
Published: May 2020

Musi River is the lifeblood of Palembang’s resident since the day kingdom of Sriwijaya. The existence of the Musi river becomes important in public life Palembang’s of resident. . Palembang city grow and develop from the banks of the Musi river. It can be seen from the structure of spatial and settlement and patterns of social life of the people which were originally all the old village oriented to the river and make the river as part of the livelihood changes and moves away from the river. Its resulted in morphological changes of space Palembang which originally Musi river as the front into the rear. As is general, the banks of the river into a desenly populated area and tend rundown. This condition is one of the causes few problems. Therefore, this research takes place on the banks of the Musi river whick crosses the city of Palembnag. This study of the research uses quaoitative research process to produce descriptive data in the form of words orspoken as a from of policy. This research’s approach is rationalistic with comparative theory settlements. This research is a study of the characteristics of settlement patterns by looking at the structure of the settelement pattern is an orientation initially Musi river settelement patterns that change with the development of infrastructure.
WACANA KEARIFAN LOKAL DALAM PENYELENGGARAAN KEBIJAKAN PEMBANGUNAN PERUMAHAN
Authors: Suryokusumo S. Beta 
Published: May 2020

Perencanaan dan perancangan lingkungan yang berkelanjutan khususnya pembangunan perumahan dan permukiman perlu dikembangkan secara positif dan berkesinambungan. Potensi wacana kearifan lokal yang dapat sinergi didalam tataran hukum positif Kebijakan Pembangunan Perumahan pada UU No.1 tahun 2011, mengenai Perumahan dan Kawasan Permukiman dan UU No.20 tahun 2011 mengenai Rumah Susun dengan kebijakan lain yang mengakomodasi aspek kearifan lokal. Dalam kajian ini dievaluasi kebijakan pembangunan perumahan dan kebijakan tata ruang dan dukungan kebijakan lainnya dalam wacana kearifan lokal. Langkah selanjutnya adalah mengevaluasi hasil survey perumahan pada tiga kegiatan lapangan unutk melihat seberapa jauh aspek kebijakan yang mengakomodasi potensi (kearifan) lokal dengan evaluasi pada studi perubahan ruang dan studi dinamika perubahan rumah pada kawasan perumahan kota di Kota Malang. Dengan metode evaluasi literatur dan empiris serta lapangan, maka padahasil survey menunjukkan bahwa aspek pembangunan perumahan masih bertumpu pada pengembangan (development), lebih dari semangat pembangunan yang berkelanjutan dari yang telah di tetapkan pada perundangan. Aspek potensi (kearifan) lokal, masih belum dimaknai dan menjawab permasalahan dilapangan. Aspek keseimbangan/kesetimbangan yang bertumpu pada Socio-community based, socio-kultural based dan socio ecology based, masih di dominasi aspek socio-economy based. Pembangunan berkelanjutan dapat terarah bilamana keterikatan pada aspek Pembangunan yang bertumpu dan mempunyai keterikatan dengan lingkungan (alam) dan mempertimbangkan nila-nilaii lain (estetika), nilai penghormatan (religius), dan nilai dari kehidupan (eksistensi). Ha-hal ini yang perlu di masukkan dalam kebijakan yang bersifat operasional sebagai bentuk penerapan dan dukungan terhadap potensi, konsepsi (kearifan) lokal.
PENATAAN SISTEM VEGETASI DI KORIDOR JALAN JAMIN GINTING PANCUR BATU
Authors: Beny O.Y Marpaung  , Destia Farahdina  
Published: May 2020

Perencanaan sistem vegetasi yang terarah untuk suatu koridor menjadi hal penting untuk dikaji, apalagi kalau koridor tersebut merupakan ruang linear yang penting dalam suatu kota. Koridor di Jalan Jamin Ginting Pancur Batu merupakan ruang linear yang signifikan bagi Kabupaten Deli Serdang karena ruang tersebut menjadi sirkulasi yang penting menuju kawasan wisata Sibolangit dan Berastagi. Keadaan sistem vegetasi pada koridor ini dapat dikatakan minim dan belum tertata dengan baik. Padahal sistem vegetasi tersebut memiliki berbagai fungsi yaitu menurunkan suhu mikro, buffer debu, filter polutan, dan peneduh untuk para pejalan kaki. Pohon peneduh merupakan faktor penting dalam menciptakan ekologis kota. Untuk itu perlu dilakukan pemilihan jenis pohon yang sesuai dengan kondisi Koridor Jalan Jamin Ginting Pancur Batu. Penelitian ini bertujuan untuk penataan jenis pohon di koridor Jalan Jamin Ginting Pancur Batu yang diharapkan dapat meningkatkan kualitas lingkungan pada koridor tersebut. Penelitian ini dilaksanakan dengan metode kualitatif deskriptif, dimana data yang diperoleh berdasarkan studi banding proyek sejenis. Proses analisa disimpulkan dengan menghubungkan permasalahan sistem vegetasi dengan studi banding dan kebijakan pemerintah. Hasil penelitian ini akan menjadi masukan bagi pemerintah Kabupaten Deli Serdang sebagai pedoman penataan sistem vegetasi. Dengan diterapkannya pedoman tersebut maka dapat menciptakan Koridor Jalan Jamin Ginting Pancur Batu sebagai salah satu kawasan yang memiliki kualitas lingkungan dan nilai estetika yang baik.