bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combining proteomics and lipid analysis to unravel Confidor stress response in Saccharomyces cerevisiae
Authors: Justinić Iva , Katić Ana , Uršičić Deni , Ćurko‐Cofek Božena , Blagović Branka , Čanadi Jurešić Gordana 
Published: November 2019

AbstractThe yeast Saccharomyces cerevisiae is a useful model for studying the influence of different stress factors on eukaryotic cells. In this work we used the pesticide imidacloprid, in the Confidor formulation, as the stress factor and analyzed its influence on the metabolic activity, proteome and lipid content and composition of Saccharomyces cerevisiae yeast. During the cultivation of yeast, the lowest recommended application dose of Confidor (0.025%, v/v) was added to the growth media and its influence on the mitochondria, cytosol with microsomes, and the whole yeast cells was monitored. The results show that under the stress provoked by the toxic effects of Confidor, yeast cells density significantly decreased and the percentage of metabolically disturbed cells significantly increased comparing with untreated control. Also, there was a downregulation of majority of glycolytic, gluconeogenesis, and TCA cycle enzymes (Fba1, Adh1, Hxk2, Tal1, Tdh1,Tdh3, Eno1) thus providing enough acetyl‐CoA for the lipid restructuring and accumulation mechanism since we have found the changes in the cell and mitochondrial lipid content and FA composition. This data suggest that lipids could be the molecules that orchestrate the answer of the cells in the stress response to the Confidor treatment.
A low‐voltage pulse electrolysis method for the degradation of anthraquinone and azo dyes in chloride medium by anodic oxidation on Ti/IrO2‐RuO2‐SnO2 electrodes
Authors: Chao Hong‐Jun , Xue Dan , Jiang Wei , Li Daosheng , Hu Zhiquan , Kang Jianxiong , Liu Dongqi 
Published: November 2019

AbstractWastewater produced by the textile industry containing azo dyes and anthraquinone dyes is significant source of pollution to the environment and is toxic for aquatic life. To overcome the high‐energy cost of traditional electrochemical oxidation, a custom‐built power supply device for the degradation of anthraquinone and azo dyes by low voltage of 15.0–20.0 V pulsed discharge was investigated. Titanium coated with mixed oxide (Ti/IrO2‐RuO2‐SnO2) plates and pure titanium plates were used as the anode and cathode, respectively, for the generation of chlorine in the dye solution. For the anthraquinone dye Reactive Blue 19, 60.0% of the chemical oxygen demand (COD) and 22.0% of the total organic carbon (TOC) were removed using this system. A comparison of the direct current electrolysis and pulsed discharge revealed that using the pulsed discharge method reduced the energy cost by 68.6%. UV–visible, LC‐MS, and GC‐MS were used to identify the intermediate compounds formed during the degradation of Reactive Blue 19. The results indicate that in the process of oxidation by chlorine/hypochlorite, the chromophore group was first oxidized to –NH2, followed by decolorization via chlorination of the aromatic rings. The results confirm that low‐voltage pulse electrolysis can be used for the degradation of industrial dyes in waste effluents.Practitioner points

Low‐voltage pulse electrolysis can be used for the degradation of industrial dyes and/or dyes in waste effluents.

For anionic dye Reactive Blue 19, 60.0% of COD and 22.0% of TOC were removed using low‐voltage (20.0 V) pulse electrolysis.

The pulsed discharge method reduced the energy cost of this degradation process by 68.6% compared with direct current electrolysis.

The intermediate compounds formed during the degradation of Reactive Blue 19 were confirmed by UV–visible spectroscopy, LC‐MS, and GC‐MS.
Asymptotic analysis of a bit brace shaped junction of thin rods
Authors: Leugering Günter , Nazarov Sergei A. , Slutskij Andrey S. , Taskinen Jari 
Published: November 2019

AbstractWe present a 1‐D model of a junction of five thin elastic rods forming the shape of a bit brace (hand drill), or, a crankshaft. The distinguishing feature of this junction is the existence of the so‐called movable elements, which are rods and knots requiring modifications of the classical asymptotic ansätze. These consist of constant longitudinal displacements on the edges of the skeleton of the junction and affect the transmission conditions at its nodes. We provide asymptotic formulas for the displacements, stresses and elastic energy, as well as error estimates. An exact solution of the model is given for a particular loading.
‘God Created Man αύτεξούσιον’: Grotius’s Theological Anthropology and Modern Contract Doctrine
Authors: Price Jonathan 
Published: November 2019

AbstractHugo Grotius, the seventeenth century Dutch scholar, is most famous for his contributions to modern international law, particularly the law of the free seas. Yet, he has had just as lasting an effect on the formation of modern contract doctrine, originating in the same text that produced his maritime law. Grotius instigates a change in the theological anthropology implicit in late scholastic contract doctrine by importing a radical sense of God-given, unfettered freedom. This he calls ‘natural liberty’. He thereby renders contractual freedom freer, as it is now liberated: from its divine telos as part of man’s salvation; from the constraints of moral philosophy; and from the need of any ultimate end. Yet, he does not set the will completely at liberty in its contractual relations; certain formal and moral constraints remain. But it is no longer required that, in order to be well used, contractual liberty must be busy building the New Jerusalem. For, its divine purposes are now more mundane: peace and order on earth, beginning with oneself. For the moral theologians who developed ‘freedom of contract’, our natural promissory powers, as manifested in contractual relations, were ordained as means contributing to our salvation. For Grotius, they had been reduced to the providential means of our survival.The great sense of natural liberty that Grotius vested in the freedom of contract would eventually open the door to radical contractual liberalization of the kind that was seen in North Atlantic nations in the nineteenth century, the primary causes of which are still disputed by scholars. In this chapter I argue that modern contract doctrine has never lost its theology of the radically free will since Grotius installed it there. If true, this theology of the will does some work in explaining the persistent liberal tendency in modern law and in modern economics (albeit not in economic theory), reducing the need to resort to naturalistic, materialistic, or ideological accounts.
Economics, Agency, and Causal Explanation
Authors: Child William 
Published: November 2019

AbstractThe paper considers three questions. First, what is the connection between economics and agency? It is argued that causation and explanation in economics fundamentally depend on agency. So a philosophical understanding of economic explanation must be sensitive to an understanding of agency. Second, what is the connection between agency and causation? A causal view of agency-involving explanation is defended against a number of arguments from the resurgent noncausalist tradition in the literature on agency and action-explanation. If agency is fundamental to economic explanation, it is argued, then so is causation. Third, what is the connection between causal explanation and the natural sciences? It is argued that, though the explanations given in economics and other social sciences are causal explanations, they are different in kind from the causal explanations of the natural sciences. On the one hand, then, the causal explanations of the social sciences are irreducible to those found in the natural sciences. On the other hand, the causal relations described by the social sciences are not completely autonomous; they do not float free of, or operate independently from, the causal relations charted by the natural sciences.
Causation and Agency
Authors: Róna Peter 
Published: November 2019

Abstract‘Causation’ covers a variety of dependent relationships between and among objects and events. The axiom concerning the unicity of reality has been thought to warrant the assumption that causal relationships of social phenomena, including economics, share common properties with corporeal objects, that, in short, agency is a form of causation. This paper defends the opposite view, to wit, that causation based on the properties and powers of corporeal objects (be they natural or man-made) is unlike causation based on agency. Whereas causation among the former is a function of the properties and powers of the objects at play, agency ‘causation’ is the product of human intentionality. Any theory of agency must account for free will even where, as in the case of rule based roles, the instantiation of free will is qualified. An agent’s action may, of course, set in motion a causal law by instantiating the properties of theobject(s)producing the intended effect (eg. pulling the trigger of a loaded gun), and the agent will be responsible for the consequences, but the discharge of the bullet is the result of the properties and powers of the gun and the bullet and not of the agent. The profound ontological difference between causation and agency cannot be overcome with resort to epistemological, logical or linguistic considerations.In economic and social life the agent relies not on the causal properties of corporeal objects, but on her action authorised bysocial rules.The causal properties and powers of objects are fundamentally different from the causal powers of rules, because, unlike the former, the latter are designed for the achievement of an intended result and cannot operate without intentional application. The proper study of economics is not the study of the properties of objects contrived by economic theory, but the nature of purposeful human action.
Shifting the System: AASPIRE and the Loom of Science and Activism
Authors: Raymaker Dora M. 
Published: November 2019

AbstractIn 2006 Dora Raymaker, Autistic person and autistic rights activist, co-founded the Academic Autism Spectrum Partnership in Research and Education (AASPIRE) with Christina Nicolaidis, a physician-researcher and parent of an autistic child. AASPIRE works within the sphere of academic health and social services research to conduct projects the A/autistic community wants done. It endeavors to return power to communities that experience oppression to make their voices heard in research and policy settings. For example, its website autismandhealth.org offers resources for autistic adults, their supporters, and healthcare providers to improve the healthcare of autistic adults in the US. AASPIRE has served as a model for community-based participatory autism research, promoting the growth of participatory autism research internationally.
From Protest to Taskforce
Authors: Murray Dinah 
Published: November 2019

AbstractFollowing the creation of APANA (‘Autistic People Against Neuroleptic Abuse,’ the creation of which is detailed in Chapter 4), Dinah Murray was called on to help deal with the unwelcome visit of Autism Speaks’ founders to Europe. The result of this second campaign was an innovative film, Something About Us, and ultimately, the creation of the UK’s National Autistic Taskforce in 2018. Thus far, it looks set to become a very active part of decision-making processes that relate to autism in the UK.
Conclusion
Authors: Kapp Steven K. 
Published: November 2019

AbstractThis concluding chapter summarizes and contextualizes the stories of events told by leaders of the autistic community and neurodiversity movement. The manifestos, mailing lists, websites or webpages, conferences, issue campaigns, academic project and journal, book, and advisory roles narrated by contributors have had significantly positive impacts on the autism landscape. Yet the contributors told their stories through words, similarly to that much neurodiversity activism takes place through language. Therefore the editor examines the most persistent critiques of the neurodiversity movement, about its representation of people with “severe” autism directly or on their behalf. The analysis mostly disputes these arguments, but finds room for improvement. The chapter ends with consideration of remaining challenges for the movement and future directions for books and scholarship on it.
Autistics.Org and Finding Our Voices as an Activist Movement
Authors: Tisoncik Laura A. 
Published: November 2019

AbstractAutistics.org was the first explicitly political website of the early autistic community. Launched in 1998 by Laura Tisoncik, its mission was to speak truths not spoken. For example, a popular section called the Institute for the Study of the Neurologically Typical satirized autism’s diagnostic criteria and assessments by spoofing them for neurotypical (NT) people. It designated “Neurotypic Disorder” or “Neurotypical Syndrome” for NTs, with elements such as the description of symptoms (e.g. suffering from socially dictated sheep-like behavior), a screening test (e.g. “Could I be NT?”), and sections of papers and abstracts that parody academic papers. Content like this exposed the stigmatizing deficit focus and power relations inherent in documents drawn up by medical authorities and elsewhere, and implied that diagnostic categories result from their cultural context.
Autscape
Authors: Buckle Karen Leneh 
Published: November 2019

Abstract
In 1996 in the United States, Autism Network International started Autreat, an annual retreat-style autistic-led conference for autistic people with allies welcome. Autscape, co-founded by Karen Leneh Buckle in 2005, is the UK version and remains a thriving meeting today. Both events have included accommodations with quiet spaces, color-coded interaction badges, and structure with the flexibility to have downtime to escape. Many autistic people met other autistic people for the first time at such events and described it as a “homecoming.” The experience has taught Buckle and other organizers the possibilities and challenges of inclusion, and she describes the developments and lessons that have made Autscape a success.
Hankel operators induced by radial Bekollé–Bonami weights on Bergman spaces
Authors: Peláez José Ángel , Perälä Antti , Rättyä Jouni 
Published: November 2019

Abstract
We study big Hankel operators $$H_f^\nu :A^p_\omega \rightarrow L^q_\nu $$

H
f
ν

:

A
ω
p

→

L
ν
q

generated by radial Bekollé–Bonami weights $$\nu $$
ν
, when $$1<p\le q<\infty $$

1
<
p
≤
q
<
∞

. Here the radial weight $$\omega $$
ω
is assumed to satisfy a two-sided doubling condition, and $$A^p_\omega $$

A
ω
p

denotes the corresponding weighted Bergman space. A characterization for simultaneous boundedness of $$H_f^\nu $$

H
f
ν

and $$H_{{\overline{f}}}^\nu $$

H

f
¯

ν

is provided in terms of a general weighted mean oscillation. Compared to the case of standard weights that was recently obtained by Pau et al. (Indiana Univ Math J 65(5):1639–1673, 2016), the respective spaces depend on the weights $$\omega $$
ω
and $$\nu $$
ν
in an essentially stronger sense. This makes our analysis deviate from the blueprint of this more classical setting. As a consequence of our main result, we also study the case of anti-analytic symbols.
Cordage, basketry and containers at the Pleistocene–Holocene boundary in southwest Europe. Evidence from Coves de Santa Maira (Valencian region, Spain)
Authors: Aura Tortosa J. Emili , Pérez-Jordà Guillem , Carrión Marco Yolanda , Seguí Seguí Joan R. , Jordá Pardo Jesús F. , Miret i Estruch Carles , Verdasco Cebrián C. Carlos 
Published: November 2019

Abstract
In this study we present evidence of braided plant fibres and basketry imprints on clay recovered from Coves de Santa Maira, a Palaeolithic-Mesolithic cave site located in the Mediterranean region of Spain. The anatomical features of these organic fibre remains were identified in the archaeological material and compared with modern Stipa tenacissima (esparto grass). Based on direct dating, the fragments of esparto cord from our site are the oldest worked plant fibres in Europe. Sixty fragments of fired clay are described. The clay impressions have allowed us to discuss the making of baskets and containers. According to their attributes and their functional interpretation, we have grouped them into five types within two broad categories, hearth plates and baskets or containers. The clay pieces identified as fragments of containers with basketry impressions are less common than those of hearth plate remains and they are concentrated in the Epipalaeolithic occupation material (13.2–10.2 ka cal bp). The clay impressions from Santa Maira indicate that some fibres were treated or flattened, a preparation process that is known from historical and ethnological sources.
Training in endocrine surgery
Authors: Gimm Oliver , Barczyński Marcin , Mihai Radu , Raffaelli Marco 
Published: November 2019

Abstract

Background/purpose
In Europe, the Division of Endocrine Surgery (DES) determines the number of operations (thyroid, neck dissection, parathyroids, adrenals, neuroendocrine tumors of the gastro-entero-pancreatic tract (GEP-NETs)) to be required for the European Board of Surgery Qualification in (neck) endocrine surgery. However, it is the national surgical boards that determine how surgical training is delivered in their respective countries. There is a lack of knowledge on the current situation concerning the training of surgical residents and fellows with regard to (neck) endocrine surgery in Europe.

Methods
A survey was sent out to all 28 current national delegates of the DES. One questionnaire was addressing the training of surgical residents while the other was addressing the training of fellows in endocrine surgery. Particular focus was put on the numbers of operations considered appropriate.

Results
For most of the operations, the overall number as defined by national surgical boards matched quite well the views of the national delegates even though differences exist between countries. In addition, the current numbers required for the EBSQ exam are well within this range for thyroid and parathyroid procedures but below for neck dissections as well as operations on the adrenals and GEP-NETs.

Conclusions
Training in endocrine surgery should be performed in units that perform a minimum of 100 thyroid, 50 parathyroid, 15 adrenal, and/or 10 GEP-NET operations yearly. Fellows should be expected to have been the performing surgeon of a minimum of 50 thyroid operations, 10 (central or lateral) lymph node dissections, 15 parathyroid, 5 adrenal, and 5 GEP-NET operations.
A Note on Nonclosed Tensor Formats
Authors: Hackbusch W. 
Published: November 2019

AbstractVarious tensor formats exist which allow a data-sparse representation of tensors. Some of these formats are not closed. The consequences are (i) possible non-existence of best approximations and (ii) divergence of the representing parameters when a tensor within the format tends to a border tensor outside. The paper tries to describe the nature of this divergence. A particular question is whether the divergence is uniform for all border tensors.
Thermoanalytical tests (TG–DTG–DSC, Py-GC/MS) of foundry binders on the example of polymer composition of poly(acrylic acid)–sodium carboxymethylcellulose
Authors: Grabowska Beata , Żymankowska-Kumon Sylwia , Cukrowicz Sylwia , Kaczmarska Karolina , Bobrowski Artur , Tyliszczak Bożena 
Published: November 2019

Abstract
The results of thermal analysis (TG–DTG–DSC) of a foundry binder from the BioCo group in the form of a polymer composition of poly(acrylic acid)–sodium carboxymethylcellulose (PAA/CMC-Na) are presented in this article. The range of temperature of degradation has been determined. It was found that as the temperature rises, physical and chemical changes take place in the binder as a result of evaporation of solvent water, release of constitutional water, intermolecular dehydration reactions and decomposition of polymer chains with the formation of gaseous decomposition products. Pyrolysis gas chromatography mass spectrometry method (Py-GC/MS) was used to identify PAA/CMC-Na binder degradation products in a predetermined temperature range based on the previously performed thermal analysis of TG–DTG–DSC. Py-GC/MS tests were also carried out to determine the emission level of gaseous products of the polymeric binder in the context of the processes occurring in the moulding (foundry) sand, in conditions of its contact with liquid metal. In addition, Py-GC/MS tests were carried out for two commonly used foundry binders based on alkaline phenolic resin cured with esters and based on urea-formaldehyde resin with furfuryl alcohol cured with sulphonic acids. The obtained Py-GC/MS results for commercial binders were referred to the results obtained for the new PAA/CMC-Na binder. It was found that the new polymer binder is characterized by the lowest emission level of gaseous products.
Asymptotics and Approximations of Ruin Probabilities for Multivariate Risk Processes in a Markovian Environment
Authors: Delsing G. A. , Mandjes M. R. H. , Spreij P. J. C. , Winands E. M. M. 
Published: November 2019

Abstract
This paper develops asymptotics and approximations for ruin probabilities in a multivariate risk setting. We consider a model in which the individual reserve processes are driven by a common Markovian environmental process. We subsequently consider a regime in which the claim arrival intensity and transition rates of the environmental process are jointly sped up, and one in which there is (with overwhelming probability) maximally one transition of the environmental process in the time interval considered. The approximations are extensively tested in a series of numerical experiments.
From path dependence to policy mixes for Nordic electric mobility: Lessons for accelerating future transport transitions
Authors: Kotilainen Kirsi , Aalto Pami , Valta Jussi , Rautiainen Antti , Kojo Matti , Sovacool Benjamin K. 
Published: November 2019

Abstract
We examine the problem of how to accelerate policies related to electric vehicles (EVs) in the Nordic countries Denmark, Finland, Norway and Sweden. These four Nordic countries represent an interesting collection of cases by virtue of having common decarbonization targets extending to the transport sector, interlinked electric energy systems and a joint electricity market largely based on low-carbon energy while they are open societies bent on innovation, making them well adaptable to a transition toward electric mobility. Our analytical framework drawing from transition research, lock-in and path dependency and institutionalism enables us to discern technological, institutional and behavioral mechanisms which can have both constraining and enabling effects vis-à-vis this transition by means of shaping national socio-technical systems and regimes. On this basis, we also discuss how to develop policies accelerating the transition. We find that the incumbent industries can shape policy choice through the lock-in into institutional inter-dependencies. The accumulation of social and material features, and vested interests of actors, for its part can maintain regime level inertia, impeding the transition. Yet, technological lock-in can also enable EVs, by means of learning effects from technologically interrelated wind energy projects and available infrastructure in buildings that support the EV charging needs. Overall, the complexity of path-dependent mechanisms embedded in the dominant regimes, together with the diversity of emerging policy mixes, demands attention both on the technologies and broader socio-technical systems in order to properly assess the prospects of transition toward electric mobility.