bluuebunny/crossref_metadata_2025_split huggingface dataset:
Different evolutionary pathways for the two subtypes of contact binaries
Authors: Zhang Xu-Dong , Qian Sheng-Bang , Liao Wen-Ping 
Published: January 2020

ABSTRACT
Secondary components of W UMa-type contact binaries (CBs) have many special properties, two of them are excess in radius and luminosity. In order to make these specialties clear, we propose radial density distribution to roughly detect the interior structure of the secondaries in CBs. By comparing the radial density distribution between secondary components of CBs and main-sequence stars, we find the radial density distribution of secondaries in A-subtype CBs are similar to main-sequence stars whose masses higher than 1.8 Msun, which suggests that these two kinds of stars may have some evolutionary relationship. While secondary components of W-subtype CBs are closely connected with stars whose masses lower than 1.8 Msun. Then, we investigate the mass–luminosity relation of secondaries in CBs, the big differences between two subtypes suggests that the overluminosity of secondaries in these two subtypes are caused by two different reasons. Overluminosity in A-subtype is because the secondary components are evolved from initial more massive stars, while in W-subtype is due to energy transfer.
LoCuSS: exploring the connection between local environment, star formation, and dust mass in Abell 1758
Authors: Bianconi M , Smith G P , Haines C P , McGee S L , Finoguenov A , Egami E 
Published: January 2020

ABSTRACT
We explore the connection between dust and star formation, in the context of environmental effects on galaxy evolution. In particular, we exploit the susceptibility of dust to external processes to assess the influence of dense environment on star-forming galaxies. We have selected cluster Abell 1758 from the Local Cluster Substructure Survey (LoCuSS). Its complex dynamical state is an ideal test-bench to track dust removal and destruction in galaxies due to merger and accretion shocks. We present a systematic panchromatic study (from $0.15\, \mu$m with GALEX to $\rm 500\, \mu$m with Herschel) of spectroscopically confirmed star-forming cluster galaxies at intermediate redshift. We observe that the main subclusters (A1758N and A1758S) belong to two separate large-scale structures, with no overlapping galaxy members. Star-forming cluster members are found preferentially outside cluster central regions, and are not isotropically distributed. Rather, these galaxies appear being funneled towards the main subclusters along separate accretion paths. Additionally, we present the first study of dust-to-stellar (DTS) mass ratio used as an indicator for local environmental influence on galaxy evolution. Star-forming cluster members show lower mean values (32$\rm {{\ \rm per\ cent}}$ at $\rm 2.4\sigma$) of DTS mass ratio and lower levels of infrared emission from birth clouds with respect to coeval star-forming field galaxies. This picture is consistent with the majority of star-forming cluster members infalling in isolation. Upon accretion, star formation is observed to decrease and warm dust is destroyed due to heating from the intracluster medium radiation, ram-pressure stripping, and merger shocks.
Three-dimensional simulations of clump formation in stellar wind collisions
Authors: Calderón D , Cuadra J , Schartmann M , Burkert A , Prieto J , Russell C M P 
Published: January 2020

ABSTRACT
The inner parsec of our Galaxy contains tens of Wolf–Rayet stars whose powerful outflows are constantly interacting while filling the region with hot, diffuse plasma. Theoretical models have shown that, in some cases, the collision of stellar winds can generate cold, dense material in the form of clumps. However, their formation process and properties are not well understood yet. In this work, we present, for the first time, a statistical study of the clump formation process in unstable wind collisions. We study systems with dense outflows (${\sim }10^{-5}\rm \ M_{\odot }\ yr^{-1}$), wind speeds of 500–$1500\rm \ km\ s^{-1}$, and stellar separations of ∼20–$200\rm \ au$. We develop three-dimensional high-resolution hydrodynamical simulations of stellar wind collisions with the adaptive-mesh refinement grid-based code ramses. We aim at characterizing the initial properties of clumps that form through hydrodynamic instabilities, mostly via the non-linear thin-shell instability (NTSI). Our results confirm that more massive clumps are formed in systems whose winds are close to the transition between the radiative and adiabatic regimes. Increasing either the wind speed or the degree of asymmetry increases the dispersion of the clump mass and ejection speed distributions. Nevertheless, the most massive clumps are very light (∼10−3–$10^{-2}\rm \ M_{\oplus }$), about three orders of magnitude less massive than theoretical upper limits. Applying these results to the Galactic Centre, we find that clumps formed through the NTSI should not be heavy enough either to affect the thermodynamic state of the region or to survive for long enough to fall on to the central supermassive black hole.
DNA-mediated coupling of ATPase, translocase and nuclease activities of a Type ISP restriction-modification enzyme
Authors: Chand Mahesh Kumar , Carle Vanessa , Anuvind K G , Saikrishnan Kayarat 
Published: January 2020

Abstract
Enzymes involved in nucleic acid transactions often have a helicase-like ATPase coordinating and driving their functional activities, but our understanding of the mechanistic details of their coordination is limited. For example, DNA cleavage by the antiphage defense system Type ISP restriction-modification enzyme requires convergence of two such enzymes that are actively translocating on DNA powered by Superfamily 2 ATPases. The ATPase is activated when the enzyme recognizes a DNA target sequence. Here, we show that the activation is a two-stage process of partial ATPase stimulation upon recognition of the target sequence by the methyltransferase and the target recognition domains, and complete stimulation that additionally requires the DNA to interact with the ATPase domain. Mutagenesis revealed that a β-hairpin loop and motif V of the ATPase couples DNA translocation to ATP hydrolysis. Deletion of the loop inhibited translocation, while mutation of motif V slowed the rate of translocation. Both the mutations inhibited the double-strand (ds) DNA cleavage activity of the enzyme. However, a translocating motif V mutant cleaved dsDNA on encountering a translocating wild-type enzyme. Based on these results, we conclude that the ATPase-driven translocation not only brings two nucleases spatially close to catalyze dsDNA break, but that the rate of translocation influences dsDNA cleavage.
Shedding of Yellow Fever Virus From an Imported Case in the Netherlands After Travel to Brazil
Authors: Phan My V T , Mendonca Melo Mariana , van Nood Els , Aron Georgina , Kreeft-Voermans Jolanda J C , Koopmans Marion P G , Reusken Chantal , GeurtsvanKessel Corine H , Cotten Matthew 
Published: January 2020

Abstract
We report yellow fever infection in a Dutch traveler returning from Brazil. Yellow fever virus (YFV) was identified in serum and urine samples over a period of 1 month. Yellow fever virus genome sequences from the patient clustered with recent Brazilian YFV and showed with limited nucleotide changes during the resolving infection.
Microsurgical Clip Ligation of an Unruptured Azygos Bifurcation Aneurysm Indented by the Falx Cerebri: 3-Dimensional Operative Video
Authors: Taylor Blake E S , Say Irene , Patel Pratit , Tomycz Luke D 
Published: January 2020

Abstract
Dissecting pericallosal aneurysms from the falx cerebri is technically challenging, as one must release the adherent dome but minimize shearing injury, which could result in intraoperative rupture. We discuss a 51-yr-old woman with a history of hypertension and smoking who presented with severe headaches and was found to have a 6-mm unruptured, multilobulated pericallosal aneurysm abutting the falx, with anterior and superior projecting domes on either side. She also had an azygos anterior cerebral artery (ACA), a rare anatomic variant associated with pericallosal aneurysms, where both A1 segments form a single A2. After considering endovascular and open surgical techniques, we proceeded with clip ligation given her younger age, smoking history, daughter aneurysms seen on angiography, and azygos ACA. We positioned her supine with her head turned lateral, left side down to maximize gravitational retraction, mapped a bicoronal incision, and performed a small craniotomy, followed by an interhemispheric approach. Rather than cutting the falx around the dome, a described technique that risks blind vessel injury, we temporarily clipped inflow vessels to reduce the dome's turgor and sharply and bluntly dissected apart its attachments, which freed the aneurysm from beneath the falx and allowed visualization of associated vessels. Using suction to manipulate the dome, we then placed stacked, angled clips, and used a micro-Doppler to confirm brisk inflow and outflow. Postoperatively, she was neurologically intact, and her angiogram showed no residual aneurysm. Our 3-dimensional video demonstrates a safer, alternative approach to treating this rare aneurysm with its associated anatomical variant. Patient consented to her clinical presentation and microscope media being used for academic purposes.
Hypoalgesic Effects of Aerobic and Isometric Motor Imagery and Action Observation Exercises on Asymptomatic Participants: A Randomized Controlled Pilot Trial
Authors: La Touche Roy , Fernández Pérez Juan José , Martínez García Sergio , Cuenca-Martínez Ferran , López-de-Uralde-Villanueva Ibai , Suso-Martí Luis 
Published: January 2020

AbstractObjectivesThe objective was to explore whether action observation (AO) and motor imagery (MI) of aerobic and isometric exercise could induce hypoalgesic responses in asymptomatic individuals compared with placebo observation (PO).MethodsA randomized controlled pilot trial was designed. Twenty-four healthy participants (mean age = 21.9 ± 2.1 years) were randomized into three groups: AO+MI (N = 8), AO, (N = 8), and PO (N = 8). All participants performed an actual aerobic running exercise (three series of 90 seconds at 85% of their VO2max and 30 seconds at 65% of their VO2max) and an isometric exercise protocol (isometric squats). A day later, they all performed the mental intervention, observing or imagining exercise execution performed the day before, according to their allocated group. Pressure pain thresholds (PPTs) of the quadriceps and epicondyle regions were assessed at baseline, postintervention, and 15 minutes postintervention.ResultsAnalysis of variance revealed statistically significant differences in the group*time interaction for PPT in the quadriceps. The AO group showed a statistically significant increase at postintervention and at 15 minutes postintervention. The AO+MI group obtained a statistically significant increase in the two PPT regions compared with the PO group at Δpre–post. The AO group obtained a greater increase in the PPT in the quadriceps femoris than the PO group at Δpre–post and Δpre–post 15 minutes.ConclusionsAO and MI induce hypoalgesic responses compared with PO. AO isolated training showed pain modulation responses in the PPTs of the quadriceps region in young physically active adults. These findings highlight the potential role of brain training in pain management.
Effects of Acetaminophen, NSAIDs, Gabapentinoids, and Their Combinations on Postoperative Pulmonary Complications After Total Hip or Knee Arthroplasty
Authors: Ohnuma Tetsu , Raghunathan Karthik , Ellis Alan R , Whittle John , Pyati Srinivas , Bryan William E , Pepin Marc J , Bartz Raquel R , Krishnamoorthy Vijay 
Published: January 2020

AbstractObjectiveMultimodal analgesia has gained popularity in total hip arthroplasty (THA) and total knee arthroplasty (TKA), but large multicenter studies evaluating specific analgesic combinations are lacking.DesignA retrospective study using the Premier Healthcare Database (2009–2014).SubjectsAdults who underwent elective primary THA or TKA.MethodsWe categorized day-of-surgery analgesic exposure using eight mutually exclusive categories: acetaminophen (Ac), nonsteroidal anti-inflammatory drugs (Ns), gabapentinoids (Ga; gabapentin or pregabalin), Ac+Ns, Ac+Ga, Ns+Ga, Ac+Ns+Ga, and none of the three drugs. Multilevel models measured associations of the analgesic categories with a composite of postoperative pulmonary complications (PPCs).ResultsAmong 863,139 patients, 75.2% received at least one of the three drugs. In multilevel models, compared with none of the three drugs, Ga use was associated with increased odds of PPCs when used alone (adjusted odds ratio [aOR] = 1.35, 95% confidence interval [CI] = 1.27 to 1.44), combined with Ac (aOR = 1.16, 95% CI = 1.08 to 1.26), or combined with Ns (aOR = 1.28, 95% CI = 1.21 to 1.34). In contrast, the Ac+Ns pair was associated with decreased odds of PPCs (OR = 0.86, 95% CI = 0.83 to 0.90) and lower opioid consumption. Ac+Ns+Ga was not associated with PPCs, whereas it was associated with the lowest opioid consumption on the day of surgery.ConclusionsGabapentinoids, alone and in single combination with either acetaminophen or nonsteroidal anti-inflammatory drugs, were associated with higher PPCs, whereas the Ac+Ns pair was associated with fewer PPCs and an opioid-sparing effect. Ac+Ns+Ga was not associated with PPCs, whereas it was associated with the lowest opioid consumption on the day of surgery.
Effect of Manual Therapy and Therapeutic Exercise Applied to the Cervical Region on Pain and Pressure Pain Sensitivity in Patients with Temporomandibular Disorders: A Systematic Review and Meta-analysis
Authors: La Touche Roy , Martínez García Sergio , Serrano García Beatriz , Proy Acosta Alejandro , Adraos Juárez Daniel , Fernández Pérez Juan José , Angulo-Díaz-Parreño Santiago , Cuenca-Martínez Ferran , Paris-Alemany Alba , Suso-Martí Luis 
Published: January 2020

Abstract

Objective
To assess the effectiveness of cervical manual therapy (MT) on patients with temporomandibular disorders (TMDs) and to compare cervico-craniomandibular MT vs cervical MT.

Design
Systematic review and meta-analysis (MA).

Methods
A search in PubMed, EMBASE, PEDro, and Google Scholar was conducted with an end date of February 2019. Two independent reviewers performed the data analysis, assessing the relevance of the randomized clinical trials regarding the studies’ objectives. The qualitative analysis was based on classifying the results into levels of evidence according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE).

Results
Regarding cervical MT, MA included three studies and showed statistically significant differences in pain intensity reduction and an increase in masseter pressure pain thresholds (PPTs), with a large clinical effect. In addition, the results showed an increase in temporalis PPT, with a moderate clinical effect. MA included two studies on cervical MT vs cervico-craniomandibular MT interventions and showed statistically significant differences in pain intensity reduction and pain-free maximal mouth opening, with a large clinical effect.

Conclusions
Cervical MT treatment is more effective in decreasing pain intensity than placebo MT or minimal intervention, with moderate evidence. Cervico-craniomandibular interventions achieved greater short-term reductions in pain intensity and increased pain-free MMO over cervical intervention alone in TMD and headache, with low evidence.
The Dynamics of the Differential Policing of Distinct Social Groups: Towards a Modern Model of Policing in Diverse Societies
Authors: Yuval Fany 
Published: January 2020

AbstractThis study investigates the different dynamics undermining the relationships between the police and four distinct groups of Israeli citizens—Arabs, ultra-Orthodox Jews, and immigrants from Ethiopia and Russia. The comparative analysis reveals the sources of inequality in policing, its characteristics, and results. The structural equation modelling elucidates that procedural justice and the effectiveness of the police shape the moral alignment between the groups and the police. These factors have different effects on the groups’ identification with the state. The results underscore the considerable importance of the government’s role in guaranteeing social inclusion and the sharing of common values. The findings may help in designing a set of reforms and training programmes—not just a single reform—suited to the special needs of each group, to cope with the challenges of equal policing in an era of global social instability.
Quantum Cohomology and Closed-String Mirror Symmetry for Toric Varieties
Authors: Smith Jack 
Published: January 2020

AbstractWe give a short new computation of the quantum cohomology of an arbitrary smooth (semiprojective) toric variety $X$, by showing directly that the Kodaira–Spencer map of Fukaya–Oh–Ohta–Ono defines an isomorphism onto a suitable Jacobian ring. In contrast to previous results of this kind, $X$ need not be compact. The proof is based on the purely algebraic fact that a class of generalized Jacobian rings associated to $X$ are free as modules over the Novikov ring. When $X$ is monotone the presentation we obtain is completely explicit, using only well-known computations with the standard complex structure.
Monthly Payment Targeting and the Demand for Maturity
Authors: Argyle Bronson S , Nadauld Taylor D , Palmer Christopher J 
Published: January 2020

Abstract
We document three phenomena we jointly refer to as monthly payment targeting. First, using data from 500,000 used auto loans and discontinuities in contract terms offered by hundreds of lenders, we show that demand is more sensitive to maturity than to interest rate, consistent with consumers managing payment size when making debt decisions. Second, many consumers appear to employ segregated mental accounts, spending exogenous payment savings on larger loans. Third, consumers bunch at round number monthly payment amounts, consistent with heuristic budgeting. That these patterns hold in subsamples of likely constrained and unconstrained borrowers challenges liquidity constraints as a complete explanation.
Treat to target and prevention of subclinical atherosclerosis in psoriatic arthritis—which target should we choose?
Authors: Cheng Isaac T , Li Edmund K , Wong Priscilla C , Law Mei Yan , Yim Isaac C , Lai Billy T , Ying Shirley K , Kwok Kitty Y , Li Martin , Li Tena K , Lee Jack J , Szeto Cheuk-Chun , Yan Bryan P , Lee Alex P , Tam Lai-Shan 
Published: January 2020

Abstract

Objective
PsA patients who achieved sustained minimal disease activity (sMDA) had less subclinical atherosclerosis progression. The vascular effects of achieving other potential treatment targets, including the PsA Disease Activity Score (PASDAS) and the Disease Activity in PsA (DAPSA) score, remained uncertain. This study aimed to compare the vascular effects of achieving different treatment targets in PsA patients.

Method
This is a post hoc analysis of a 2 year treat-to-target study aimed at MDA. A total of 101 consecutive PsA patients without overt cardiovascular disease were recruited. High-resolution carotid ultrasound and arterial stiffness markers were assessed annually. Low disease activity (LDA) was defined as MDA, DAPSA ≤14 or PASDAS ≤3.2. Sustained disease control was defined as achieving these targets at each visit from month 12 until month 24.

Results
Ninety patients [52 male (57.8%), age 50 years (s.d. 11)] who completed 24 months of follow-up were included in this analysis. A total of 44%, 48% and 45% of patients achieved sustained DAPSA LDA (sDAPDA-LDA), sustained PASDAS LDA (sPASDAS-LDA) and sMDA, respectively. Patients who achieved sMDA had significantly less progression of carotid intima-media thickness than those who did not (P = 0.031). Using multivariate analysis, achieving sMDA and sPASDAS-LDA had a protective effect on plaque progression, less increase in total plaque area, reduced mean intima-media thickness and reduced augmentation index after adjusting for covariates. In contrast, no significant differences in the progression of vascular parameters were demonstrated between patients who did or did not achieve sDAPSA-LDA.

Conclusion
Achieving sMDA/sDASPAS-LDA, but not sDAPSA-LDA, was associated with a protective effect in subclinical atherosclerosis and arterial stiffness progression. A multidimensional domain of disease control might be better in minimizing cardiovascular risk in PsA.
AUTOMATIC BRAIN DOSE ESTIMATION IN COMPUTED TOMOGRAPHY USING PATIENT DICOM IMAGES
Authors: Gharbi Souha , Labidi Salam , Mars Mokhtar 
Published: January 2020

AbstractThis study aims to develop an Automatic Brain Dose Estimation (ABDE) methodology for head computed tomography examinations. The ABDE is to be applied first to an anthropomorphic Alderson phantom to obtain a Correction factor (Cf) between the ABDE and the direct absorbed brain dose using dosemeters positioned within the anthropomorphic phantom. Then, in order to estimate the correct brain dose for patient, the Cf was multiplied by the mean ABDE values for each patient. Results were compared to those registered with a mathematical simulation phantom using CT-Expo V 2.4 software. Results showed no significant difference between the correct ABDE values and the CT–Expo values with a mean percent difference of 2.54 ± 0.01%. In conclusion, ABDE yields a correct estimation of brain dose, taking into account the size and attenuation of the irradiated region. Thus, it is clinically recommended for accurate patient brain dose assessment.
Let it be: mindful acceptance down-regulates pain and negative emotion
Authors: Kober Hedy , Buhle Jason , Weber Jochen , Ochsner Kevin N , Wager Tor D 
Published: January 2020

Abstract
Mindfulness training ameliorates clinical and self-report measures of depression and chronic pain, but its use as an emotion regulation strategy—in individuals who do not meditate—remains understudied. As such, whether it (i) down-regulates early affective brain processes or (ii) depends on cognitive control systems remains unclear. We exposed meditation-naïve participants to two kinds of stimuli: negative vs. neutral images and painful vs. warm temperatures. On alternating blocks, we asked participants to either react naturally or exercise mindful acceptance. Emotion regulation using mindful acceptance was associated with reductions in reported pain and negative affect, reduced amygdala responses to negative images and reduced heat-evoked responses in medial and lateral pain systems. Critically, mindful acceptance significantly reduced activity in a distributed, a priori neurologic signature that is sensitive and specific to experimentally induced pain. In addition, these changes occurred in the absence of detectable increases in prefrontal control systems. The findings support the idea that momentary mindful acceptance regulates emotional intensity by changing initial appraisals of the affective significance of stimuli, which has consequences for clinical treatment of pain and emotion.