bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using a geographic and interdisciplinary strategy to improve patient care outcomes.
Authors: Philip Tony , Karlin-Zysman Corey , Rimar Alex , Liberman Tara , Cardoza Donna , Carleton Jane E. , Devoe Craig E. 
Published: October 2019

78 Background: Long Island Jewish Medical Center at Northwell Health is an urban/suburban academic tertiary care hospital located across the street from the Northwell Health Cancer Institute. The Division of Hospital Medicine partnered with Hematology/Oncology and Palliative Care to co-manage inpatient oncology patients on a geographic unit. The goal was to improve patient care through co-ownership and co-accountability of cancer patients in conjunction with a unit-based collaboration with Nursing, Pharmacy, Social Work, Case Management and Physical Therapy. Methods: A unit-based, interdisciplinary care team was formed consisting of Medical Oncologists, Hospitalists, Palliative Care specialists, Radiation Oncologists, as well as unit based and specialty trained nurses, social workers and advanced care practitioners. The team meets Monday thru Friday during interdisciplinary rounds to collaboratively discuss the care plans of each patient. We recently added a hospital-based medical oncologist to support greater continuity and communication. Results: Since full implementation including improvements in patient cohorting, the oncology care model has resulted in a 20% reduction in Medicare readmissions, a significant reduction in CAUTIs and CLABSIs, a 50% reduction in C.diff, a decreased CMI-adjusted length of stay and an improvement in pain management HCAHP scores, despite a 10% increase in CMI. An interdisciplinary approach has also improved documentation of goals of care discussion from 6% to 40-58%, furthering the idea of providing a unified medical voice to a vulnerable population. Conclusions: The oncology care model highlights that implementing multidisciplinary rounding, co-management and population-based geography can deliver a higher quality and more efficient level of care even in the face of higher patient acuity.
Nonthyroidal Illness Syndrome Across the Ages
Authors: Langouche Lies , Jacobs An , Van den Berghe Greet 
Published: October 2019

AbstractIn conditions of acute illness, patients present with reduced plasma T3 concentrations without a concomitant rise in TSH. In contrast, plasma concentrations of the inactive hormone rT3 increase, whereas plasma concentrations of T4 remain low-normal. This constellation of changes, referred to as nonthyroidal illness syndrome (NTIS), is present across all ages, from preterm neonates and over-term critically ill infants and children to critically ill adults. Although the severity of illness strongly correlates with the severity of the NTIS phenotype, the causality of this association remains debated, and pathophysiological mechanisms remain incompletely understood. In the acute phase of illness, NTIS appears to be caused predominantly by an increased peripheral inactivation of thyroid hormones, in which reduced nutritional intake plays a role. Current evidence suggests that these acute peripheral changes are part of a beneficial adaptation of the body to reduce expenditure of energy and to activate the innate immune response, which is important for survival. In contrast, in more severely ill and prolonged critically ill patients, an additional central suppression of the thyroid hormone axis alters and further aggravates the NTIS phenotype. Recent studies suggest that this central suppression may not be adaptive. Whether treatment of this central component of NTIS in prolonged critically ill patients, with the use of hypothalamic releasing factors, improves outcome remains to be investigated in large randomized control trials.
“An Observance of Silence to the Events”
Authors: Johnson Shelby 
Published: October 2019

AbstractJuliet Granville, the protagonist of Frances Burney’s novel The Wanderer (1814), enters the novel fleeing the French Revolution and disguised in blackface. This article argues that Juliet’s act of racial counterfeiting implicitly gestures toward the Haitian Revolution without naming that historical touchstone and emblematizes a theory of trace histories that Burney articulates in the novel’s dedication. There, she sketches an agonistic vision of history through what she calls “traces,” where events “though already historical, have left traces” that have been “handed down . . . from generation to generation” and tarry in the present. Burney frames the trace as an afterlife of an event that cannot be quite integrated into the broader scope of “history” as such but which leaves behind profound formal remainders. Burney’s dedication thus theorizes how to read Romantic-era novels for those fragments of form, and Juliet’s disguise replots erasures of Caribbean history as a problem of reading.
Lipidomics reveal the protective effects of a vegetable-derived isothiocyanate against retinal degeneration
Authors: Kwa Faith A. , Dulull Nabeela K. , Roessner Ute , Dias Daniel A. , Rupasinghe Thusitha W. 
Published: October 2019

Background:Age-related macular degeneration (AMD) is a leading cause of blindness in the ageing population. Without effective treatment strategies that can prevent disease progression, there is an urgent need for novel therapeutic interventions to reduce the burden of vision loss and improve patients’ quality of life. Dysfunctional innate immune responses to oxidative stress observed in AMD can be caused by the formation of oxidised lipids, whilst polyunsaturated fatty acids have shown to increase the risk of AMD and disease progression in affected individuals. Previously, our laboratory has shown that the vegetable-derived isothiocyanate, L-sulforaphane (LSF), can protect human adult pigment epithelial cells from oxidative damage by upregulating gene expression of the oxidative stress enzyme Glutathione-S-Transferase µ1. This study aims to validate the protective effects of LSF on human retinal cells under oxidative stress conditions and to reveal the key players in fatty acid and lipid metabolism that may facilitate this protection.Methods:Thein vitrooxidative stress model of AMD was based on the exposure of an adult retinal pigment epithelium-19 cell line to 200µM hydrogen peroxide. Percentage cell proliferation following LSF treatment was measured using tetrazolium salt-based assays. Untargeted fatty acid profiling was performed by gas chromatography-mass spectrometry. Untargeted lipid profiling was performed by liquid chromatography-mass spectrometry.Results:Under hydrogen peroxide-induced oxidative stress conditions, LSF treatment induced dose-dependent cell proliferation. The key fatty acids that were increased by LSF treatment of the retinal cells include oleic acid and eicosatrienoic acid. LSF treatment also increased levels of the lipid classes phosphatidylcholine, cholesteryl ester and oxo-phytodienoic acid but decreased levels of phosphatidylethanolamine lipids.Conclusions:We propose that retinal cells at risk of oxidative damage and apoptosis can be pre-conditioned with LSF to regulate levels of selected fatty acids and lipids known to be implicated in the pathogenesis and progression of AMD.
Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection
Authors: Crosnier Cecile , Brandt Cordelia , Rinaldi Gabriel , McCarthy Catherine , Barker Colin , Clare Simon , Berriman Matt , Wright Gavin J. 
Published: October 2019

Background: Schistosomiasis is a major parasitic disease affecting people living in tropical and sup-tropical areas. Transmission of the parasite has been reported in 78 countries, causing significant morbidity and around 200,000 deaths per year in endemic regions. The disease is currently managed by the mass-administration of praziquantel to populations at risk of infection; however, the reliance on a single drug raises the prospect of parasite resistance to the only treatment widely available. The development of an effective vaccine would be a more powerful method of control, but none currently exists and the identification of new immunogens that can elicit protective immune responses therefore remains a priority. Because of the complex nature of the parasite life cycle, identification of new vaccine candidates has mostly relied on the use of animal models and on a limited set of recombinant proteins. Methods: In this study, we have established an infrastructure for testing a large number of vaccine candidates in mice and used it to screen 96 cell-surface and secreted recombinant proteins from Schistosoma mansoni. This approach, using standardised immunisation and percutaneous infection protocols, allowed us to compare an extensive set of antigens in a systematic manner. Results: Although some vaccine candidates were associated with a statistically significant reduction in the number of eggs in the initial screens, these observations could not be repeated in subsequent challenges and none of the proteins studied were associated with a strongly protective effect against infection. Conclusions: Although no antigens individually induced reproducible and strongly protective effects using our vaccination regime, we have established the experimental infrastructures to facilitate large-scale systematic subunit vaccine testing for schistosomiasis in a murine infection model.
COSMETICS USAGE HABITS AND RELATED SIDE EFFECTS AMONG FEMALES: LITHUANIAN CASE
Authors: Šniepienė Gražina , Jonuševičienė Judita 
Published: October 2019

Background. Nowadays, it is generally recognized that physical appearance is important, women are particularly interested in their aesthetic appearance and the use of various cosmetic products. The long-term usage habits of cosmetic products have influenced not only the condition of the skin and hair but also on human health.
The aim of the survey was to investigate cosmetics use habits and related side effects among females.
Methods: A quantitative survey was performed; an original questionnaire based on scientific resources was used, used data collection method - a written survey. Survey sample – 336 Lithuanian women. Data analysis was performed using the social research statistics program SPSS 25.0. Percentage frequencies were calculated for ordinal variables - averages and standard deviations. The Pearson’s Chi-Square test and the non-parametric Kruskal Wallis and Mann Whitney tests were used to detect statistically significant differences. The significance level selected was p <0.05.
Results. The survey revealed the prevalence and frequency of the use of cosmetic products by women, as well as the choice criteria for selecting cosmetic products. The side effects related to the use of cosmetics experienced by women are investigated as well as some practices and habits regarding the use of cosmetics.
Conclusions. The study shows that the choice criteria of cosmetic products differ among separate women age groups. The older women are more concerned about the composition of the products, their naturalness, and the manufacturer, while the price is less important. Most commonly used are personal hygiene products including deodorants and perfumers. The older women use less cosmetic products (p <0.05) than the younger ones. The majority of women have experienced side effects related to the use of cosmetics. The study shows that the occurrence of side effects does not depend on the number of products used. However, they are related to the use habits: women who experience side effects more often (p <0.05) use expired cosmetic products. In addition, women with side effects are less likely to use cosmetic testers.
INFLUENCE OF TECHNOLOGICAL PARAMETERS OF THE ULTRAFILTRATION PROCESS OF CITRUS JUICES ON THEIR QUALITY
Authors: Bejanidze Irina , Kharebava Tina , Nakashidze Nunu , Komcelidze Lamzira , Davitadze Nazi 
Published: October 2019

Fresh fruit juices contain organic acids and mineral substances (potassium, calcium, iron, copper, magnesium, phosphorus, manganese, molybdenum, boron, iodine), and their salts, large amounts of fiber, pectin and enzymes - complex substances, that contribute to the food processing and absorption of nutritional elements. Natural citrus juices contain essential vitamins and nutrients for the human body. Therefore, they represent a good opportunity for the treatment and prevention of various diseases. With the vitamins, taken through the juice, the human body becomes more resistant to viruses and infections, stressful situations and intense physical stress, and the body’s metabolism becomes normalized. Beverages, prepared from juices improve intestinal motility and thus contribute to improving the allocation of toxic substances and slags from the organism.
The purpose of this work is the development of technological parameters of the ultrafiltration process to obtain natural juices which are sterile, resistant to precipitation and turbidity, and have a long shelf life. This paper examines the performance of the ultrafiltration process of citrus juices (lemon, tangerine, orange) and its dependence on the pressure and duration of the process, type and porosity of the membrane, the nature of the juice, and acidity. The juice composition was studied before and after ultrafiltration. It was established, that the productivity of the ultrafiltration process depends on: the duration of the process and this dependence is determined by the nature of the process: membrane type, in particular, filtration material and pressure: with an increase in membrane porosity and pressure, the productivity of the process, the volume of filtered juice, filtering speed and duration increases; the productivity of the ultrafiltration process, during the filtration both in dynamic and static mode, depends on the type and consistency of the juice: it increases with the increase of juice acidity. It was established: the general acidity (1.17%), density (1.038 g/cm3), the content of dry substances (9.9%), sugars (7.8%), including invert (7.2%), ash ( 0.26%), and vitamin C ( 20mg/ 100gr.), do not change in the course of ultrafiltration of tangerine juice. The viscosity, the content of carotenoids, cellulose and pectin decreases. The amino-acid structure practically does not change; hollow fibers detain only 6 - 8% of proteins and amino acids. For obtaining high-quality citrus juices, ultrafiltration should be carried out at a pressure 0.2MPa, on hollow fiber, in a dynamic, circulating mode.
The juices obtained by ultrafiltration on hollow fibers (AP-2.0) are sterile, resistant to precipitation and turbidity, have significantly increased shelf lives, and they retain their organoleptic properties and nutritional values.
CHARACTERIZATION OF SEVERAL WEST GEORGIAN AUTOCHTHONOUS GRAPES AND THEIR WINE STILBENES
Authors: Kharadze Maia , Vanidze Maia , Djaparidze Indira , Kalandia Givi , Davitadze Ruslan , Kalandia Aleko 
Published: October 2019

The present study was conducted to determine the content of Stilbenes in the several autochthonous West Georgian grapes and wines. Stilbenes were analyzed using HPLC-UV samples and were prepared using resin (amberlite XAD2) column, C18 Cartridge Solid Phase Extraction (SPE) Waters Sep-Pak C18 (500 mg). The identification was achieved using UPLC-PDA and MS analysis. The study was conducted on the following Stilbenes and their derivatives – Astringin, Piceid, Trans/cis resveratrol, and ε-Viniferin. The amount of stilbenes in grapes was determined as: Aladasturi-131.9±4.8 mg kg-1, Aleksandrouli 148.2±4.9 mg kg-1, Mujuretuli 215.3±7.9 mg kg-1 , Chkhaveri 77.5 ±2.5 mg kg-1, Ojaleshi 260.71±9.1mg kg-1 . In red wines the content of Stilbenes was Aladasturi-19.17±0.5 mg kg-1, Aleksandrouli 14. 87±0.4 mg kg-1, Mujuretuli 21.36±0.5 mg kg-1, Chkhaveri 14.5±0.4 mg kg-1, Ojaleshi 60.8±2.2 mg kg-1.
Targeted, Precision Irrigation for Moving Platforms: Selected Papers from a Center Pivot Technology Transfer Effort
Authors: Lamm Freddie R. , Porter Dana O. , Bordovsky James P. , Evett Steven R. , O’Shaughnessy Susan A. , Stone Kenneth C. , Kranz William L. , Rogers Danny H. , Colaizzi Paul D. 
Published: October 2019

Abstract. This article is an introduction to an ASABE Special Collection of ten articles concerning center pivot (CP) technology transfer that appears in this issue of and in . The year 2018 marked the 40th anniversary of research and development of low-energy precision application (LEPA) for use with CP sprinkler irrigation systems. Since 1978, researchers, extension specialists, and industry have continued development of multiple technologies that are suitable for mobile lateral irrigation platforms. A two-year technology transfer effort with funding from the USDA-ARS Ogallala Aquifer Program (OAP) was initiated in January 2017 to promote adoption of advanced and efficient irrigation technologies and to highlight recommended practices for mobile irrigation platforms, including both CP and lateral-move (LM) systems. The articles in this Special Collection address five major topic areas: in-canopy and near-canopy irrigation application from moving platforms, site-specific variable-rate irrigation (VRI) and associated sensor technologies for moving platforms, the use of variable-frequency drives (VFDs) with CP systems, and uniformity evaluations for CP systems. While these ten articles are not inclusive of all the important advances in irrigation from moving platforms since 1978, they illustrate that continued improvement in irrigation management occurs by combining engineering and agronomic sciences. Pressurized irrigation from moving platforms is increasing in the U.S. and will be an important tool for meeting global food and water challenges. In addition to introducing and summarizing the Special Collection, this article provides additional rationale for the CP technology transfer effort. Keywords: Center pivot, Irrigation uniformity, Lateral-move sprinkler, LEPA, Linear-move sprinkler, Low-energy precision application, Site-specific irrigation, Sprinkler irrigation, Variable-frequency drives, Variable-rate irrigation, VFD, VRI.
Microbial Population Change in Anaerobic Digestion during Copper Sulfate Inhibition and Recovery
Authors: Jordaan Elsie M. , Levin David B. , Sparling Richard , Khafipour Ehsan , Çiçek Nazim 
Published: October 2019

Abstract. This study evaluated how feedstock with added copper sulfate (commonly used as an antimicrobial footbath solution in livestock operations) changed the performance and microbial populations of a dairy manure digester. High-throughput Illumina sequencing of the V4 region of the bacterial and the V6-V8 regions of the archaeal 16S rRNA gene in digester samples showed a significant change in the microbial community composition during addition of feedstock with copper sulfate, followed by a return to the original composition with regular feedstock. Bacterial genera that were suppressed during the inhibition period included Cloacamonas, Syntrophomonas, Butyrivibrio, and Caldicoprobacter, while the relative abundance of Acholeplasma, Desulfobulbus, Aminobacterium, Treponema, and YRC22 peaked. The dominant methanogen Methanosarcina, although initially resistant, was suppressed during inhibition, while Methanobrevibacter and Methanosphaera, prominent feedstock genera, increased. The return of the bacterial and archaeal communities to compositions similar to their previous steady states after inhibition highlights the digester’s microbial resilience and recovery potential. Keywords: . Anaerobic digestion, Copper sulfate inhibition, Illumina sequencing, Manure, Methanogens, Microbial populations, Microbiome.
“Who is that masked man?”
Authors: Alberts Jeffrey R. 
Published: October 2019

In 1933, The Lone Ranger was a favorite on U.S. radios. In 1946, the show debuted on the new medium of television and became a cultural icon in the States. The Lone Ranger character was a mysterious, heroic cowboy. He wore a black mask and did good with humble anonymity. At the end of each episode, after a successful, selﬂess exploit, as our hero rode oﬀ on his white steed with his trusted Indian companion, grateful townspeople would ask, “Who is that masked man?”
POLITIK BALAS BUDI, BUAH SIMALAKAMA DALAM DEMOKRASI AGRARIA DI INDONESIA
Authors: Puri Widhiana Hestining 
Published: October 2019

Pemilihan umum menjadi instrumendemokrasiyang berprinsip dari, oleh, dan untuk rakyat. Kompetisi dan komunikasi jamak dilakukan dalam meraih dukungan, salah satu caranya dengan memanfaatkanpolitik etis atau politik balas budi. Filosofi masyarakat timur yang menjunjung tinggi kebersamaan dan solidaritas mendorong hal ini relatif efektif dalam mobilisasi massa. Permasalahan muncul manakala hal ini harus dibayar mahal oleh masyarakat dengan pola kepemimpinan pemerintahan yang tidak aspiratif. Dukungan masyarakat diperlukan, namun jangan sampai menjadi bumerang yang merugikan masyarakat apalagi jika melanggar ketentuan undang-undang. Melalui model penelitian hukum normatif/ deskstudy, ditemukan bahwa demokrasi di tingkat desa mempertemukan nilai tradisional masyarakat dengan hukum formal yang modern. Hal ini pada akhirnya akan mengancam upaya pencapaian keadilan agraria bagi masyarakat.
STRATEGI PEMBERDAYAAN MASYARAKAT DALAM PENGELOLAAN HUTAN MANGROVE
Authors: Mahmudah Siti , Badriyah Siti Malikhatun , Turisno Bambang Eko , Soemarmi Amiek 
Published: October 2019

Pemanfaatan hutan mangrove merupakan hak masyarakat yang dijamin dalam Undang-Undang, yang memerlukan pemberdayaan masyarakat. Pembahasan ini ditujukan untuk mengetahui strategi pemberdayaan masyarakat dalam pengelolaan hutan mangrove dengan metode penulisan yuridis normatif, spesifikasi penulisan deskriptif analitis yang menggunakan data sekunder, analisis kualitatif. Strategi pemberdayaan masyarakat dalam pengelolaan hutan mangrove melalui metode persuasif, edukatif, dan fasilitatif yang terdapat dalam kemitraan usaha dalam Undang-Undang Nomor 20 Tahun 2008 Tentang Usaha Mikro, Kecil, dan Menengah, yang dilaksanakan dengan PP No 17 Tahun 2013 dimana dapat dilaksanakan dengan berbagai pola kemitraan. Pola-pola kemitraan tersebut dapat digunakan dalam pemberdayaan masyarakat pesisir pengelola hutan mangrove, pemilihan pola kemitraan yang akan digunakan disesuaikan dengan kebutuhan masyarakat setempat.
On the exact multiplicity of stable ground states of non-Lipschitz semilinear elliptic equations for some classes of starshaped sets
Authors: Díaz J.I. , Hernández J. , Ilyasov Y.Sh. 
Published: October 2019

AbstractWe prove the exact multiplicity of flat and compact support stable solutions of an autonomous non-Lipschitz semilinear elliptic equation of eigenvalue type according to the dimension N and the two exponents, 0 <α<β< 1, of the involved nonlinearites. Suitable assumptions are made on the spatial domainΩwhere the problem is formulated in order to avoid a possible continuum of those solutions and, on the contrary, to ensure the exact number of solutions according to the nature of the domainΩ. Our results also clarify some previous works in the literature. The main techniques of proof are a Pohozhaev’s type identity and some fibering type arguments in the variational approach.