bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pyralis cardinalis, a charismatic new species related to P. regalis [Denis &amp; Schiffermüller], 1775, first recognized in Finland (Lepidoptera, Pyralidae)
Authors: Wikström Bo , Huemer Peter , Mutanen Marko , Tyllinen Juha , Kaila Lauri 
Published: November 2020

The informal Pyralis regalis complex, including species of the genus Pyralis Linnaeus, 1758 (Pyralidae), with a bright white or silvery pattern on the forewing, is reviewed, supplemented by observations of the externally distinguished P. perversalis (Herrich-Schäffer, 1849), which also exhibits similarities in genitalia and DNA barcodes.
We describe Pyralis cardinalis Kaila, Huemer, Mutanen, Tyllinen &amp; Wikström, sp. nov., based on specimens ranging from Denmark and Sweden in the West to Japan and South Korea in the East. A neotype is designated for the predominantly South European P. regalis [Denis &amp; Schiffermüller], 1775. Lectotypes are designated for Asopia kacheticalis Christoph, 1893 and Pyralis princepsButler, 1889. Pyralis regalis ssp. sagarrai Leraut, 2005 is considered a valid species, stat. nov.
Topography-Guided Custom Ablation Photorefractive Keratectomy Treatment of Irregular Astigmatism Resulting From Decentered SMILE
Authors: Wiley Lee A. , Randleman J. Bradley 
Published: November 2020

PURPOSE:
To describe the use of topography-guided custom ablation treatment with photorefractive keratectomy (T-CAT PRK) to correct irregular astigmatism and visual aberrations resulting from decentered small incision lenticule extraction (SMILE).

METHODS:
Case report and literature review.

RESULTS:
A 41-year-old woman experienced blurred uncorrected distance acuity (UDVA), reduced corrected distance acuity (CDVA), and monocular diplopia in one eye following SMILE due to treatment decentration. Retrospective review of the surgical video provided visual cues to the impending decentration at multiple points during the docking process and lenticule creation. Re-treatment was performed using T-CAT PRK with mitomycin C application with off-label use of the EX500 excimer laser (Alcon Laboratories, Inc). Treatment resulted in improvement in UDVA and CDVA to 20/12; reduced higher order aberrations, particularly vertical coma (−0.65 µm to 0.197 µm); topographic pattern centration; and subjective symptom resolution.

CONCLUSION:
Recognition of subtle visual cues at the time of SMILE docking can provide critical feedback to avoid treatment decentration. T-CAT PRK can be a useful treatment option when decentration occurs.

[
J Refract Surg
. 2020;36(11):766–771.]
Evaluation of the clinical profile, laboratory parameters and outcome of two hundred COVID-19 patients from a tertiary centre in India
Authors: Gupta Nitesh , Ish Pranav , Kumar Rohit , Dev Nishanth , Yadav Siddharth Raj , Malhotra Nipun , Agrawal Sumita , Gaind Rajni , Sachdeva Harish , COVID 2019 working group *Other members of the Safdarjung Hospital 
Published: November 2020

COVID-19 is a pandemic with over 5 million cases worldwide. The disease has imposed a huge burden on health resources. Evaluation of clinical and epidemiological profiles of such patients can help in understanding and managing the outbreak more efficiently. This study was a prospective observational analysis of 200 diagnosed COVID-19 patients admitted to a tertiary care center from 20th march to 8th May 2020. All these patients were positive for COVID-19 by an oro-nasopharyngeal swab-rtPCR based testing. Analyses of demographic factors, clinical characteristics, comorbidities, laboratory parameters, and the outcomes were performed. The mean age of the population was 40 years with a slight male predominance (116 patients out of 200, 58%). A majority of the patients (147, 73.5 %) were symptomatic, with fever being the most common symptom (109, 54.5%), followed by cough (91, 45.5%). An older age, presence of symptoms and their duration, leukocytosis, a high quick SOFA score, a high modified SOFA score, need for ventilator support, an AST level more than 3 times the upper limit of normal (ULN), and a serum creatinine level of 2 mg/dl or greater were at a significantly higher risk of ICU admission and mortality. Presence of diabetes mellitus, AST > three times ULN, serum creatinine 2 mg/dl or higher, and a qSOFA score of 1 or higher were all associated with significantly greater odds of critical care requirement. Triage and severity assessment helps in deciding the requirement for a hospital stay and ICU admission for COVID-19 which can easily be done using clinical and laboratory parameters. A mild, moderate and severe category approach with defined criteria and treatment guidelines will help in judicious utilization of health-care resources, especially for developing countries like India.

*Other members of the Safdarjung Hospital COVID-19 working group: Balvinder Singh (Microbiology), MK Sen (Pulmonary Medicine), Shibdas Chakrabarti (Pulmonary Medicine), NK Gupta (Pulmonary medicine), AJ Mahendran (Pulmonary Medicine), Ramesh Meena (Medicine), G Usha (Anaesthesiology), Santvana Kohli (Anaesthesiology), Sahil Diwan (Anaesthesiology), Rushika Saksena (Microbiology), Vikramjeet Dutta (Microbiology), Anupam Kr Anveshi (Microbiology)
Abdominal Tuberculosis: Experience from Two Tertiary-Care Hospitals in the Paris Region
Authors: Calin Ruxandra , Belkacem Anna , Caraux-Paz Pauline , Wagner Mathilde , Guillot Héène , Veziris Nicolas , Jaureguiberry Stéphane , Caumes Eric , Patey Olivier , Pourcher Valérie 
Published: November 2020

ABSTRACTAbdominal tuberculosis (ATB) is uncommon and not very well known by clinicians. We describe the characteristics, evolution, and treatment of patients with ATB in two large hospitals in the Paris region. We reviewed all records of patients treated for ATB, from January 01, 2010 to December 01, 2016, diagnosed by bacteriological and/or histological methods or highly suspected because of clinical/radiological features. We included 80 patients, with a median (IQR) age of 39 (29–50) years, with 56.2% being males. Among them, 63.7% had African origins, 15% Asian, and 11.2% European. Twenty-nine had a cause of immunosuppression (n = 21 HIV infection). The main abdominal localizations were lymph nodes (72.5%), peritoneum (62.5%), and solid organs (25%). Extra-abdominal localizations were recorded in 65 (81.2%) patients. Tuberculosis was proven bacteriologically in 71%, histologically in 50%, and solely clinical/radiological in 10% of cases. Patients received standard therapy for a median duration of 9 months, with a favorable outcome. Corticosteroid therapy was used in 15 cases, either for paradoxical reaction or to prevent complications. Abdominal TB was mainly represented by lymphatic and peritoneal localizations, proven bacteriologically, and associated with extra-abdominal localizations in most cases. The use of steroids remains controversial, but it does not seem systematically needed in case of abdominal involvement.
Apresentação do Dossiê
Authors: Monteiro Silva Igor , Sá Barreto Francisco , Denise Silva Lara 
Published: November 2020

Apresentação do dossiê temático "Compondo cidades: engajamentos possíveis entre expressões culturais e mobilizações políticas", organizado pelos(as) pesquisadores(as) Igor Monteiro, Francisco Sá Barreto e Lara Denise Silva.
A REVIEW ON LIPOMA AND ITS GENETIC INTERVENTIONS
Authors: Jisa Elizabath Sabu  , Bharat Mishra  , Angelin Jaimon Augustine  , Aleesha R  
Published: November 2020

Lipomas are benign soft tissue fatty tumours that most commonly appear in the third decade of life when fatty tissue accumulates. Histologically, lipoma is composed of mature fat cells with a thin fibrous capsule. Simple lipomas account for 80% of adipose tissue tumours. The aetiology may be genetic like Familial Multiple Lipomatosis. Some tumours, like the well differentiated Liposarcomas never metastasize unless they undergo de-differentiation. They can be introduced as Atypical Lipomatous Tissue, ALT. Southern blot analysis is performed by obtaining DNA from ALT, cases in which most of them are characterized by the presence of supernumerary ring and long marker chromosomes. The complex chromosome region contains genes MDM2, CDK4, HMGI- C, SAS, GLI, CHOP, OS4 and OSP. Most of ALTs, after analysis revealed amplification of CDK4 and MDM2 proto- oncogenes that play major role in permitting over ride of block operated on cell proliferation. Immuno-histochemical results have shown MDM2 over expression in about 50% of ALTs along with weak CDK4 immuno-positivity. Also the lipomas with Gene fusion transcripts have the expression of certain genes, HMGA2/LPP, HMGA2/RDCI and HMGA2/NFIB. Of these 98% of cases were analyzed for the possible expression of HMGA2/LPP and LPP- HMGA2 fusion genes using reverse transcription polymerase chain reaction. Over all these cases, shows non-enhanced adipocyte apoptosis and enhanced adipogenesis in lipoma tissue. Thus studies provide insights into molecular pathogenesis of lipomatous tumour and representation of distinctive subset of mesenchymal neoplasms with mature adipocyte differentiation.
Integração ensino-serviço na formação técnica de enfermagem
Authors: Franco Miriam Trombetta , Millão Luzia Fernandes 
Published: November 2020

Os técnicos de Enfermagem compõem a maior parcela de profissionais no setor saúde, logo sua formação e atuação merecem atenção. A integração ensino-serviço funciona como estratégia para reorganização simultânea, tanto do mundo da formação profissional quanto do mundo do trabalho. Esta pesquisa objetivou compreender a integração ensino-serviço na formação técnica em Enfermagem e utilizou-se de método qualitativo, exploratório-descritivo. Para estudo das informações, foram realizadas entrevistas coletivas com 34 participantes, sendo gestores, professores, estudantes e profissionais. Para tratamento das informações, utilizou-se análise de conteúdo. Verificou-se que a integração ensino-serviço, pode beneficiar a formação e a atuação profissional, entretanto há desafios a serem superados para consolidação de sua proposta. Conclui-se que, não há uma estrutura institucionalizada que norteie as práticas, tornando as instituições parceiras entre si, em uma postura dialógica e construtiva, com pactuação bilateral de objetivos, abrindo oportunidades para qualificação da assistência em saúde.
Descritores: Educação Técnica em Enfermagem; Serviços de Integração Docente-Assistencial; Educação em Enfermagem.
Belgisch gekissebis rondom de familie Oranje-Nassau
Authors: Karapetian G. 
Published: November 2020

Belgisch gekissebis rondom de familie Oranje-Nassau
De familie Oranje-Nassau is op grond van het decreet van 24 november 1830 eeuwig uitgesloten van het bekleden van een openbaar ambt in België. In deze bijdrage wordt aandacht besteed aan dit decreet. Vooreerst wordt ingegaan op enkele wetstechnische aspecten, namelijk het rechtskarakter van het decreet en de mogelijkheid en wijze van afschaffing. Vervolgens komt de conformiteit van het decreet met verdragsrechtelijke discriminatieverboden ter sprake.
A forecast model for prevention of foodborne outbreaks of non-typhoidal salmonellosis
Authors: Rojas Fernando , Ibacache-Quiroga Claudia 
Published: November 2020

BackgroundThis work presents a forecast model for non-typhoidal salmonellosis outbreaks.MethodThis forecast model is based on fitted values of multivariate regression time series that consider diagnosis and estimation of different parameters, through a very flexible statistical treatment called generalized auto-regressive and moving average models (GSARIMA).ResultsThe forecast model was validated by analyzing the cases ofSalmonella entericaserovar Enteritidis in Sydney Australia (2014–2016), the environmental conditions and the consumption of high-risk food as predictive variables.ConclusionsThe prediction of cases ofSalmonella entericaserovar Enteritidis infections are included in a forecast model based on fitted values of time series modeled by GSARIMA, for an early alert of future outbreaks caused by this pathogen, and associated to high-risk food. In this context, the decision makers in the epidemiology field can led to preventive actions using the proposed model.
Weed Dynamics in Maize (Zea mays L.) as Influenced by Pre and Post-emergence Herbicides under Temperate Conditions of Western Himalayan Region
Authors: Rasool Faisul-ur- , Bhat M. I. , Dar Z. A. , Hakeem S. A. , Nasseer S. , Bashir S. , Nisa Seerat-ul- , Majeed S. , Rashid Z. , Iqbal S. , Lone B. A. , Haq Ansar-ul- , Kumar Sanjay 
Published: November 2020

Field experiments were conducted in 2017-18 during main cropping seasons of the year 2017 and 2018 at Dryland (Karewa) Agriculture Research Station, SKUAST-K to determine the effect of different post and pre emergence herbicides application on weed dynamics in maize (Zea mays L.). The experiment was laid out in randomized block design with four replications and variety used was Bio-605. Five treatments Five treatments viz, Atrazine 50% WP @ 1.0 kg ha-1 as pre-emergence and Paraquat dichloride 24% SL @ 0.5 kg ha-1, 2,4-D sodium salt 58% WSC @ 1.0 kg ha-1 as post-emergence herbicides (application at 2-3 leaf stage of weeds), hand weeding as standard check and weedy check as control were used. Effect of different herbicides on weed density was found significant. in plots managed with hand weeding, no weed was recorded. The Atrazine treated plots @ 1.0 kg ai ha-1 as pre-emergence had the weed population of 5.51, 5.4, 3.73, 5.12, 4.28 and 41.4m-2 , respectively in Echinochloa spp., Eleusine indica, Digitaria sanguinalis, Amaranthus viridis, Sorghum halepense and Cyperus spp. However, the maximum population of weeds was recorded in weedy check with 21.54 m-2, 20.87 m-2, 19.16 m-2, 21.5 m-2, 16.7 m-2 and 60.7 m-2. No significant difference was observed between Paraquat dichloride 24% SL @ 0.5 kg ai ha-1 and 2,4- D Sodium salt 58% WSC @ 1.0 kg ai ha-1 except for Cyperus spp. with density of 51.37 m-2 and 43.04 m-2 respectively. The potential of the atrazine in controlling weeds thereby enhancing yield of maize was found in this study.
Computed Tomography Findings at 6th Month Related to Chronic Anastomotic Complications After Rectal Surgery
Authors: Kang Sung Il , Kim Jae Hwang , Kim Sohyun 
Published: November 2020

Objective
This study aimed to assess a radiologic test and clinical findings as risk factors of chronic complications after anastomotic leakage (CCAL) in rectal surgery.

Summary of Background Data
Anastomotic leakage (AL) is the most important complication that is related to chronic complications like unhealed chronic sinuses, strictures, and infections.

Methods
This retrospective study included patients who developed anastomotic leakage (AL) after undergoing extraperitoneal anastomosis. Patients with the following characteristics were excluded: (1) patients with no anastomoses, (2) patients undergoing multiple resections due to synchronous colorectal lesions, (3) patients with no curative resections of the primary lesions, and (4) patients experiencing immediate postoperative mortality. Finally, 72 patients were analyzed in this study. The patients were divided into the no chronic complication (NCC) group and the chronic complication (CC) group.

Results
Of the 72 included patients, 17 (23.6%) had CCAL. The patients in the CC group more frequently had radiotherapy and lower tumor compared to the patients in the NCC group. A total of 52 (52/55 [94.5%]) and 4 patients (4/17 [23.5%]) in the NCC group and the CC group achieved bowel continuity 3 years after the primary surgery, respectively (P &lt; 0.0001). According to the multivariate analysis, CT findings at the sixth postoperative month and tumor height were associated with CCAL (P &lt; 0.0001 and P = 0.046, respectively).

Conclusion
This study showed that CT findings at the 6th postoperative month and tumor height were possibly associated with CCAL.
Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products
Authors: Krushkal Julia , Negi Simarjeet , Yee Laura M. , Evans Jason R. , Grkovic Tanja , Palmisano Alida , Fang Jianwen , Sankaran Hari , McShane Lisa M. , Zhao Yingdong , O'Keefe Barry R. 
Published: November 2020

Natural products remain a significant source of anticancer chemotherapeutics. The search for targeted drugs for cancer treatment includes consideration of natural products, which may provide new opportunities for antitumor cytotoxicity as single agents or in combination therapy. We examined the association of molecular genomic features in the well‐characterized NCI‐60 cancer cell line panel with in vitro response to treatment with 1302 small molecules which included natural products, semisynthetic natural product derivatives, and synthetic compounds based on a natural product pharmacophore from the Developmental Therapeutics Program of the US National Cancer Institute's database. These compounds were obtained from a variety of plant, marine, and microbial species. Molecular information utilized for the analysis included expression measures for 23059 annotated transcripts, lncRNAs, and miRNAs, and data on protein‐changing single nucleotide variants in 211 cancer‐related genes. We found associations of expression of multiple genes including SLFN11, CYP2J2, EPHX1, GPC1, ELF3, and MGMT involved in DNA damage repair, NOTCH family members, ABC and SLC transporters, and both mutations in tyrosine kinases and BRAF V600E with NCI‐60 responses to specific categories of natural products. Hierarchical clustering identified groups of natural products, which correlated with a specific mechanism of action. Specifically, several natural product clusters were associated with SLFN11 gene expression, suggesting that potential action of these compounds may involve DNA damage. The associations between gene expression or genome alterations of functionally relevant genes with the response of cancer cells to natural products provide new information about potential mechanisms of action of these identified clusters of compounds with potentially similar biological effects. This information will assist in future drug discovery and in design of new targeted cancer chemotherapy agents.
Observation of Supercavity Modes in Subwavelength Dielectric Resonators
Authors: Odit Mikhail , Koshelev Kirill , Gladyshev Sergey , Ladutenko Konstantin , Kivshar Yuri , Bogdanov Andrey 
Published: November 2020

AbstractElectromagnetic response of dielectric resonators with high refractive index is governed by optically induced electric and magnetic Mie resonances facilitating confinement of light with the amplitude enhancement. Traditionally, strong subwavelength trapping of light was associated only with plasmonic or epsilon‐near‐zero structures, which however suffer from material losses. Recently, an alternative localization mechanism was proposed allowing the trapping of light in individual subwavelength optical resonators with a high quality factor in the regime of a supercavity mode. Here, the experimental observation of the supercavity modes in subwavelength ceramic resonators in the radio‐frequency range is presented. It is experimentally demonstrated that the regime of supercavity modes can be achieved via precise tuning of the resonator's dimensions. A huge growth of the unloaded quality factor is achieved with experimental values up to 1.25 × 104, limited only by material losses of ceramics. It is revealed that the supercavity modes can be excited efficiently both in the near‐ and far‐field. In both cases, the supercavity mode manifests itself explicitly as a Fano resonance with characteristic peculiarities of spectral shape and radiation pattern. A comparison of supercavities made of diversified materials for the visible, infrared, THz, and radio‐frequency regimes is provided.
A Solvent‐Exchange Strategy to Regulate Noncovalent Interactions for Strong and Antiswelling Hydrogels
Authors: Xu Liju , Gao Shan , Guo Qirui , Wang Chen , Qiao Yan , Qiu Dong 
Published: November 2020

AbstractPhysical hydrogels from existing polymers consisting of noncovalent interacting networks are highly desired due to their well‐controlled compositions and environmental friendliness; and therefore, applied as adhesives, artificial tissues, and soft machines. Nevertheless, these gels have suffered from weak mechanical strength and low water resistance. Current methodologies used to fabricate these hydrogels mainly involve the freezing–thawing process (cryogels), which are complicated in preparation and short in adjustment of polymer conformation. Here, taking the merits of noncovalent bonds in adjustability and reversibility, a solvent‐exchange strategy is developed to construct a class of exogels. Based on the exchange from a good solvent subsequently to a poor one, the intra‐ and interpolymer interactions are initially suppressed and then recovered, resulting in dissolving and cross‐linking to polymers, respectively. Key to this approach is the good solvent, which favors of a stretched polymer conformation to homogenize the network, forming cross‐linked hydrogel networks with remarkable stiffness, toughness, antiswelling properties, and thus underwater adhesive performance. The exogels highlight a facile but highly effective strategy of turning the solvent and consequently the noncovalent interactions to achieve the rational design of enhanced hydrogels and hydrogel‐based soft materials.
Three‐Dimensional Photoengraving of Monolithic, Multifaceted Metasurfaces
Authors: Kang Hong Suk , Jolly Jason Christopher , Cho Hyesung , Kalpattu Abhishek , Zhang Xu A. , Yang Shu 
Published: November 2020

AbstractMetasurfaces present a potent platform to manipulate light by the spatial arrangement of sub‐wavelength patterns with well‐defined sizes and geometries, in thin films. Metasurfaces by definition are planar. However, it would be highly desirable to integrate metasurfaces with diverse, spatially programmed sub‐wavelength features into a 3D monolith, to manipulate light within a compact 3D space. Here, a 3D photoengraving strategy is presented; that is, generation of such composite metasurfaces from a single microstructure via the irradiation of multiple interference laser beams onto different facets of the parent azopolymeric microstructure. Through “photofluidization,” this technique enables independent inscription and erasing of metasurfaces onto and from individual facets of 3D monoliths with arbitrary shapes and dimensions, in a high‐throughput fashion (over approximately a few cm2 at a time). By engraving discrete sub‐wavelength 1D surface relief gratings of different pitches on different facets of an inverse pyramidal array, a multiplexing structure‐color filter is demonstrated.
Luminescent Ratiometric Thermometers Based on a 4f–3d Grafted Covalent Organic Framework to Locally Measure Temperature Gradients During Catalytic Reactions
Authors: Kaczmarek Anna M. , Jena Himanshu Sekhar , Krishnaraj Chidharth , Rijckaert Hannes , Veerapandian Savita K. P. , Meijerink Andries , Van Der Voort Pascal 
Published: November 2020

AbstractCovalent Organic Frameworks (COFs), an emerging class of crystalline porous materials, are a new type of support for grafting lanthanide ions (Ln3+), which can be employed as ratiometric luminescent thermometers. In this work we have shown that COFs co‐grafted with lanthanide ions (Eu3+, Tb3+) and Cu2+ (or potentially other d‐metals) can synchronously be employed both as a nanothermometer and catalyst during a chemical reaction. The performance of the thermometer could be tuned by changing the grafted d‐metal and solvent environment. As a proof of principle, the Glaser coupling reaction was investigated. We show that temperature can be precisely measured during the course of the catalytic reaction using luminescence thermometry. This concept could be potentially easily extended to other catalytic reactions by grafting other d‐metal ions on the Ln@COF platform.