bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expression pattern of MRPS18 family genes in malignantly transformed b-cells
Authors: Kovalevska L. , Kashuba E. 
Published: December 2020

Summary. Aim: To compare expression patterns of proteins of a family of mitochondrial ribosomal protein S18 (MRPS18) in tumor cell lines of the B-cell origin. Materials and Methods: The study has been performed on different subsets of tonsil B-cells and tumor cell lines of the B-cell origin using quantitative polymerase chain reaction analysis, western blot analysis, immunohistochemistry, bioinformatic analysis of the publicly available data bases on expression. Results: We have found that genes of the MRPS18 family (1–3) show different expression patterns in tumor cell lines of the B-cell origin. The highest levels of expression were shown for MRPS18-3, the lowest — for MRPS18-1. MRPS18-2 was expressed at the highest levels in germinal center cells, Burkitt lymphoma and Hodgkin lymphoma cell lines. At the protein levels, MRPS18-2 showed the highest expression in Burkitt lymphoma and B-cell precursor acute lymphoblastic leukemia cell lines. In lymphoblastoid cell lines, and in germinal center B-cells MRPS18-2 levels were somewhat lower, but higher than in memory and plasma B-cells. Conclusions: The differential expression pattern of the MRPS18 family proteins suggests that they play various roles in cellular processes.
Persepsi Pelaku UMKM terhadap Penggunaan Aplikasi Akuntansi Berbasis Android
Authors: Mahrus Moh Luthfi , Almadia Faralisa , Jelita Nadhira Bunga 
Published: December 2020

This study aims to understand the perceived usefulness and ease of using MSME business owners towards the android-based SME Accounting application. This study uses a qualitative method with the Technology Acceptance Model approach. This study's findings indicate that in terms of perceived usefulness, most MSME players state that the android-based MSME accounting application is useful in recording daily operational transactions because it can automate the recording and preparation of financial reports. However, in terms of perceived ease to use, android-based accounting applications are still relatively difficult to use, especially for those who do not have accounting education. As a result, MSME players are still loyal to the manual recording system and are not yet interested in using android-based accounting applications. Therefore, the government needs to work with android-based accounting application developers and related parties to continue improving accounting applications and disseminate information to MSME players, both in terms of using these applications and in terms of accounting understanding.ABSTRAKStudi ini bertujuan untuk memahami persepsi kegunaan dan persepsi pelaku UMKM terhadap aplikasi Akuntansi UKM berbasis android. Studi ini menggunakan metode kualitatif dengan pendekatan Technology Acceptance Model. Temuan studi ini menunjukkan bahwa dari sisi persepsi kegunaan, sebagian besar pelaku UMKM menyatakan bahwa aplikasi Akuntansi UMKM berbasis android berguna dalam pencatatan transaksi operasional sehari-hari karena mampu mengotomasi pencatatan dan penyusunan laporan keuangan. Namun demikian, dari sisi persepsi kemudahan, aplikasi akuntansi berbasis android dirasa masih relatif sulit untuk digunakan, khususnya bagi pihak yang tidak mempunyai latar belakang pendidikan akuntansi. Akibatnya, para pelaku UMKM masih setia pada sistem pencatatan manual dan belum berminat untuk menggunakan aplikasi akuntansi berbasis android. Oleh karena itu, pemerintah perlu bekerja sama dengan pengembang aplikasi akuntansi berbasis android dan para pihak terkait untuk terus menyempurnakan aplikasi akuntansi serta melakukan sosialisasi kepada para pelaku UMKM, baik dari segi penggunaan aplikasi tersebut maupun dari segi pemahaman akuntansi.
Peran Kualitas Layanan dan Kepercayaan Dalam Membangun Kepuasan dan Loyalitas Pelanggan
Authors: Fakhrana Zahra 
Published: December 2020

This study aims to understand the role of service quality and trust in developing customer satisfaction and loyalty at JNE Margonda, Depok. The research is used as a quantitative approach. Respondents are 127 people who were taken by purposive sampling technique. This study uses Structural Equation Modeling (SEM) with Lisrel 8.80 applications for analyzing the data. All three hypotheses are accepted, and the data supports the model. H1: service quality has a positive and significant effect on customer satisfaction. H2: Trust has a positive and significant impact on customer satisfaction. H3: Customer satisfaction has a positive and significant effect on customer loyalty. The Conclusion: (1) The high quality of service from JNE Margonda Depok increases customer satisfaction (2) If trust in JNE Margonda Depok is high, then higher customer satisfaction will be higher too; (3) Respondents who feel satisfied when using JNE Margonda services will be more loyal to JNE Margonda Depok ABSTRAKPenelitian ini bertujuan untuk mengetahui pengaruh kualitas layanan dan kepercayaan terhadap kepuasan dan loyalitas pelanggan JNE Margonda, Depok. Penelitian dilakukan dengan pendekatan kuantitatif. Responden sejumlah 127 orang yang diambil dengan teknik purposive sampling. Analisis data menggunakan Structural Equation Modeling (SEM) dengan aplikasi Lisrel 8.80. Tiga hipotesis penelitian ini diterima semua, data mendukung model. H1: Kualitas layanan memiliki pengaruh positif dan signifikan terhadap kepuasan pelanggan. H2: Kepercayaan memiliki pengaruh positif dan signifikan terhadap kepuasan pelanggan. H3: Kepuasan pelanggan memiliki pengaruh positif dan signifikan terhadap loyalitas pelanggan. Kesimpulan : (1) Kualitas layanan yang tinggi dari JNE Margonda Depok meningkatkan kepuasan pelanggan; (2) Semakin percaya responden terhadap JNE Margonda Depok akan semakin tinggi pula kepuasan pelanggannya; 3) Kepuasan yang tinggi dari pelanggan akan membuat pelanggan semakin loyal terhadap JNE Margonda Depok
MENINGKATKAN KETERAMPILAN DAN POTENSI MASYARAKAT MELALUI PEMBERDAYAAN MASYARAKAT
Authors: Permana Sutisna Setya , Khodijah Parinduri Siti 
Published: December 2020

Mahasiswa sebagai agen perubahan memiliki tanggungjawab yang besar untuk bisa memberikan manfaat bagi masyarakat dan lingkungannya. Salah satu kegiatan yang bisa dilakukan adalah melakukan pemberdayaan masyarakat. Kegiatan ini dilakukan dengan metode sosialisasi, pemberian edukasi, praktek dan pemberian fasilitas. Pelaksanaan KKN dimulai dari tanggal 6 Agustus 2019 sampai dengan 6 September 2019 di Desa Wangunjaya Kecamatan Leuwisadeng Kabupaten Bogor. Program KKN kelompok 35 dan 36 di Desa Wangun Jaya merupakan program yang lebih menekankan kepada Kualitas Sumber Daya dan Mutu Pendidikan. Kegiatan fisik kelompok 35 dan 36 yaitu pemberian dan pemasangan papan nama jalan, pembuatan Gardu Desa dan pembuatan alat pembakar sampah (Incinerator). Dan kegiatan non fisik kelompok 35 dan 36 antara lain Cek Kesehatan Gratis, Penyuluhan Cuci Tangan yang Baik dan Benar, Jum’at Bersih, Bimbingan Belajar, Pelatihan Komputer Dasar (MS. Office dan MS Excel), Penyuluhan Tabungan Dini, Kewirausahaan, Pelaksanaan kegiatan TPA, Lomba 17 Agustusan, dan Panggung Gembira.
Control interno como herramienta eficiente para la gestión financiera y contable de las empresas camaroneras
Authors: Sotomayor Alexandra , Criollo Kelvin , Gutiérrez Nestor 
Published: December 2020

El presente estudio hace énfasis en el problema central de las empresas camaroneras que actualmente se ven afectadas con la falta de un control interno adecuado a sus transacciones, provocando inconvenientes de índole contable que dan lugar a la necesidad de implementar un sistema de control interno basado a su contabilidad. El objetivo es determinar la manera en que el control interno ayuda a mejorar la gestión contable y financiera de las diferentes empresas camaroneras de la ciudad de Machala, provincia de El Oro. El marco de referencia bibliográfica expone los diferentes conceptos relacionados con el tema del control interno y la importancia que tiene el mismo en las empresas de cualquier actividad. A través de la metodología, se describen las técnicas, métodos, instrumentos como la encuesta y las unidades investigativas utilizadas para la recopilación de la información, lo que generará las bases para conocer la situación administrativa y contable de las empresas camaroneras, finalmente se analizaron e interpretaron los resultados, donde se reflejan los indicadores de las variables del tema de estudio para la verificación de los objetivos, para ello la guía de encuestas dio lugar a conocer la visión de los objetos de estudios involucrados sobre el control interno de las empresas camaroneras y se concluye que el personal del área contable debe de conocer y estar en capacidad de aplicar en su contabilidad las normas y reglamentos, además de realizar correctivos en los procesos contables, y sobre todo en las actividades de control que se encuentran ausentes en las empresas, objeto de estudio por lo que su nivel de definición es muy general para orientar el ejercicio de control de manera efectiva. No existen prácticas de control interno para todos los procesos, y los pocos que existen no son aplicados adecuadamente en los casos que se presentan.
Coaching como herramienta fundamental dentro de las empresas comerciales
Authors: Granja Edison , Angel Kevin , Tapia Nancy , Pacheco Andrés 
Published: December 2020

En la presente investigación se va a determinar la incidencia que tiene la herramienta coaching en las empresas comerciales de la ciudad de Machala. Se presenta un marco teórico acorde de la investigación para una mejor comprensión del tema, además la metodología utilizada para este trabajo es de enfoque cuantitativo. El tamaño de la muestra se lo calculó en base a la fórmula de la población infinita. Los resultados obtenidos mediante la utilización del software estadístico SPSS y Excel ayudaron a evidenciar la influencia de la herramienta coaching para cada una de las empresas comerciales. Gracias a los análisis de los resultados que arrojó la tabulación de datos, se pudo determinar la incidencia de la herramienta coaching en las empresas comerciales.
Towards Export-Led Growth in The West Africa Sub Region Economies
Authors: Ayeni Raphael Kolade 
Published: December 2020

The policy of import substitution dominated developing economies especially Sub-Sharan African countries up till 1970. The focus later shifted to pursuing growth through increased export. Recently, countries of the West Africa Sub-region are clamoring for a revisit of growth through import substitution policies. This study therefore delved into the question of whether ECOWAS countries should go for import substitution growth strategy, or to develop strategy that promotes export-led growth, following the law of comparative advantage or a considerable mix of the two strategies. Using an export-augmented neoclassical production function, the study tested how relevant is the Export-led Growth Hypothesis for the ECOWAS sub-region over the period 1980-2014.
Evidence does not offer a strong support for the Hypothesis in the short run but a strong evidence for improved capital stock and labor causing growth. However, long-run results suggest a significant relationship between export and growth but currently negative. A likely explanation of this negativity is that although exports, in the West African sub-regions has the tendency of increasing growth in the long run along with other factors of production, the present conditions of export, especially manufactured and agricultural exports, is experiencing a kind of “Import surge”. That is the import content of exports is high and the local content is low, thus reducing the spillover or multiplier effects. This was confirmed by the strong bilateral causality between export and import discovered in this study. A policy mix of import substitution and export promotion strategies was recommended for countries in this sub-region. Policies that will promote technological innovation in manufacturing and linkages with local suppliers alongside incentives to produce towards export are imperative. Production towards export should be focused on manufactured and agricultural products where each country has the highest comparative advantage so as to reduce the import content of the export.
THE POST-PANDEMIC ECONOMIC-INTERDEPENDENCE CONUNDRUM OF CPO-BASED INDUSTRY
Authors: Mulyaman Darynaufal , Kogoya Rudi , Adam Mikhail 
Published: December 2020

The COVID-19 pandemic worldwide is halting every economic activity—no exception for the industry that related or originated from crude palm oil (CPO). Planting, harvesting, processing, and even industries that require oil palm as the main or supporting raw material have been delayed or choked up due to this pandemic. Many health problems originate from the destruction of nature due to the excessive extraction of natural resources. This over-extraction causes alarming natural degradation. Many things, from pandemics to global warming, pose challenges due to this ancient economic pattern. Furthermore, environmental degradation gave birth directly or indirectly to COVID-19. Many scholars said the CPO planting and harvesting is affecting the natural environment badly. Hence, a new pandemic could be born out of this. Korea, as one of the rising manufacturing economies in Asia, also needs CPO for some of its industries to some extent, like food and cosmetics. Due to the growing demand for K-Pop byproducts, food and cosmetic industries in Korea need to catch up on the market even during and post the pandemic. Thus, with the growing concern of the natural environment in the post-pandemic world, then how it will impact the Korean food and cosmetic industry, which may need a lot of CPO as one of the sources or raw materials for production? In this paper, we argue that the economic interdependence of the global supply chain remains persistent despite adjustments and shifts due to the COVID-19 pandemic. This research was conducted in a descriptive qualitative manner with the economic interdependence paradigm as the main basis for presenting the arguments for this case's analysis.

Keywords: CPO, Korea, Economic Interdependence, Post-Pandemic, COVID-19
ANALYSING AND MAPPING OF LAND FIRE VULNERABILITY IN KUMPEH, MUARO JAMBI DISTRICT, JAMBI PROVINCE
Authors: Kurniawan Farhan , Risdiyanto Idung , Turyanti Ana 
Published: December 2020

Forest and land fires have become disasters that have received international attention. Peatland as an important part of the forest poses a separate threat to the effect of carbon release and climate change. Fire prevention can be done by understanding the causes. Fire vulnerability mapping uses several parameters in its calculation, namely NDVI value, NDMI value, TWI value, accessibility distance, and community activity center. Land use and hotspot history will be the parameters compared with the results of the analysis. The calculation uses a range of values ​​from 1 to 5. The risk level class is divided into five, with the highest percentage of 20.18% at the very vulnerable level and the lowest of 19.56% at the normal level. Very vulnerable areas have the highest number of hotspot points at 268 points while the lowest number of hotspot points is in the safe class of 23 points. Most areas with high vulnerability are found in agriculture and plantation areas. The model used in this fire vulnerability map can be said to have a pretty good correlation.

Keywords: accessibility distance, forest fires, hotspot, land use, peatland
PENGARUH KUALITAS LAYANAN CUSTOMER SERVICE TERHADAP KEPUASAN NASABAH PADA PT. BANK RAKYAT INDONESIA UNIT DOPING SENGKANG PROVINSI SULAWESI SELATAN
Authors: Ibadurrahman Hastutianti Abdul Hafid 
Published: December 2020

Kualitas pelayanan yang diberikan akan sangat mempengaruhi kepuasan dari nasabah, semakin baik layanan yang diberikan maka semakin besar pula kemungkinan nasabah merasakan kepuasan atas layanan yang diberikan. Tujuan penelitian ini untuk mengetahui pelayanan customer service pada nasabah Bank Rakyat Indonesia Unit Doping Sengkang Provinsi Sulawesi Selatan. Populasi dalam penelitian ini adalah seluruh Frontline officer pada Kantor Bank Rakyat Indonesia Unit Doping Sengkang Provinsi Sulawesi Selatan sebanyak 108 dan sampel sebanyak 47 orang. Analisis data yang digunakan adalah regresi sederhana. Hasil penelitian menunjukkan koefisien determinasi (Adjusted R square) adalah 0,673 yang mengandung pengertian bahwa kualitas layanan customer berpengaruh sebesar 67,3% terhadap kepuasan nasabah. Sedangkan sisanya sebesar 33,7% dipengaruhi oleh faktor lain yang tidak diteliti dalam penelitian ini. Tingkat signifikan dari kualitas layanan customer adalah 0,00 < 0,05 yang berarti terdapat pengaruh signifikan dari variabel kualitas layanan customer service terhadap kepuasan nasabah pada PT. Bank Rakyat Indonesia Unit Doping Sengkang Provinsi Sulawesi Selatan. Dengan Demikian Ha diterima dan Ho ditolak.
An in vitro Evaluation of the Effect of Transient Electromagnetic Fields on Pacemakers and Clinical Mitigation Measures
Authors: Huang Jing , Lin Kaibin , Lu Wu , Ding Ranran , Wu Bingjie , Cai Mingqi , Nazarian Saman , Zhao Wenbin , Li Jingbo , Huang Dong 
Published: December 2020

Background: The effect of transient electromagnetic fields on the function of pacemakers is not well-evaluated. There is a lack of effective methods for clinicians to reduce electromagnetic susceptibility (EMS) during implantation of pacemakers. This study aimed to evaluate whether a novel method of handling the excess leads in the pocket can lower the EMS of pacemakers and consequently reduce the effect of electromagnetic interference caused by transient electromagnetic fields on pacemakers.Methods: An in vitro chest model was established to simulate the clinical condition of dual-chamber pacemaker implantation. Three different intertwining patterns of excess leads were examined: parallel, twisted once, and multiple twisted-pair. Oscillated currents were injected into a copper electrical wire set horizontally above the model to create a radiated magnetic field to simulate the transient daily electromagnetic exposure of pacemakers. The electromagnetic induction of current was measured. The occurrence of EMS-related adverse events was evaluated when the induced pulsed voltage was applied.Results: Transient electromagnetic fields can induce electromagnetic noise in the pacing loop and inhibit the release of pacing pulses. The multiple twisted-pair intertwining pattern of excess leads was associated with a lower induced voltage amplitude than both the parallel and once-twisted patterns (P &lt; 0.001). Even once twisted could significantly reduce induced voltage amplitude compared to not twisted (P &lt; 0.001). A lower incidence of pacing inhibition was also observed in the multiple twisted-pair group than in the other two groups (P &lt; 0.001).Conclusions: Transient electromagnetic fields can cause pacing inhibition. Twisting the excess leads for multiple turns in the pocket is an effective method to reduce the EMS of the dual-chamber pacemaker.
Three Immune-Associated Subtypes of Diffuse Glioma Differ in Immune Infiltration, Immune Checkpoint Molecules, and Prognosis
Authors: Zhou Quanwei , Yan Xuejun , Liu Weidong , Yin Wen , Xu Hongjuan , Cheng Damei , Jiang Xingjun , Ren Caiping 
Published: December 2020

Diffuse glioma is one of the most prevalent malignancies of the brain, with high heterogeneity of tumor-infiltrating immune cells. However, immune-associated subtypes of diffuse glioma have not been determined, nor has the effect of different immune-associated subtypes on disease prognosis and immune infiltration of diffuse glioma patients. We retrieved the expression profiles of immune-related genes from The Cancer Genome Atlas (TCGA) (n = 672) and GSE16011 (n = 268) cohorts and used them to identify subtypes of diffuse glioma via Consensus Cluster Plus analysis. We used the limma, clusterProfiler, ESTIMATE, and survival packages of R for differential analysis, functional enrichment, immune and stromal score evaluation respectively in three subtypes, and performed log-rank tests in immune subtypes of diffuse glioma. The immune-associated features of diffuse glioma in the two cohorts were characterized via bioinformatic analyses of the mRNA expression data of immune-related genes. Three subtypes (C1–3) of diffuse glioma were identified from TCGA data, and were verified using the GSE16011 cohort. We then evaluated their immune characteristics and clinical features. Our mRNA profiling analyses indicated that the different subtypes of diffuse glioma presented differential expression profile of specific genes and signal pathways in the TCGA cohort. Patients with subtype C1, who were mostly diagnosed with grade IV glioma, had poorer outcomes than patients with subtype C2 or C3. Subtype C1 was characterized by a higher degree of immune cell infiltration as estimated by GSVA, and more frequent wildtype IDH1. By contrast, subtype C3 included more grade II and IDH1-mutated glioma, and was associated with more infiltration of CD4+T cells. Most subtype C2 had the features between subtypes C1 and C3. Meanwhile, immune checkpoints and their ligand molecules, including PD1/(PD-L1/PDL2), CTLA4/(CD80/CD86), and B7H3/TLT2, were significantly upregulated in subtype C1 and downregulated in subtype C3. In addition, patients with subtype C1 exhibited more frequent gene mutations. Univariate and multivariate Cox regression analyses revealed that diffuse glioma subtype was an effective, independent, and better prognostic factor. Therefore, we established a novel immune-related classification of diffuse glioma, which provides potential immunotherapy targets for diffuse glioma.