bluuebunny/crossref_metadata_2025_split huggingface dataset:
NiMn‐Based Bimetal–Organic Framework Nanosheets Supported on Multi‐Channel Carbon Fibers for Efficient Oxygen Electrocatalysis
Authors: Cheng Weiren , Lu Xue Feng , Luan Deyan , Lou Xiong Wen (David) 
Published: July 2020

AbstractDeveloping noble‐metal‐free bifunctional oxygen electrocatalysts is of great significance for energy conversion and storage systems. Herein, we have developed a transformation method for growing NiMn‐based bimetal–organic framework (NiMn‐MOF) nanosheets on multi‐channel carbon fibers (MCCF) as a bifunctional oxygen electrocatalyst. Owing to the desired components and architecture, the MCCF/NiMn‐MOFs manifest comparable electrocatalytic performance towards oxygen reduction reaction (ORR) with the commercial Pt/C electrocatalyst and superior performance towards oxygen evolution reaction (OER) to the benchmark RuO2 electrocatalyst. X‐ray absorption fine structure (XAFS) spectroscopy and density functional theory (DFT) calculations reveal that the strong synergetic effect of adjacent Ni and Mn nodes within MCCF/NiMn‐MOFs effectively promotes the thermodynamic formation of key *O and *OOH intermediates over active NiO6 centers towards fast ORR and OER kinetics.
Outer‐Membrane Protease (OmpT) Based E. coli Sensing with Anionic Polythiophene and Unlabeled Peptide Substrate
Authors: Sinsinbar Gaurav , Gudlur Sushanth , Wood Sarah E. , Ammanath Gopal , Yildiz Hakan U. , Alagappan Palaniappan , Mrksich Milan , Liedberg Bo 
Published: July 2020

AbstractE. coli and Salmonella are two of the most common bacterial pathogens involved in foodborne and waterborne related deaths. Hence, it is critical to develop rapid and sensitive detection strategies for near‐outbreak applications. Reported is a simple and specific assay to detect as low as 1 CFU mL−1 of E. coli in water within 6 hours by targeting the bacteria's surface protease activity. The assay relies on polythiophene acetic acid (PTAA) as an optical reporter and a short unlabeled peptide (LL37FRRV) previously optimized as a substrate for OmpT, an outer‐membrane protease on E. coli. LL37FRRV interacts with PTAA to enhance its fluorescence while also inducing the formation of a helical PTAA‐LL37FRRV construct, as confirmed by circular dichroism. However, in the presence of E. coli LL37FRRV is cleaved and can no longer affect the conformations and optical properties of PTAA. This ability to distinguish between an intact and cleaved peptide was investigated in detail using LL37FRRV sequence variants.
Rational Control of Charge Transfer Excitons Toward High‐Contrast Reversible Mechanoresponsive Luminescent Switching
Authors: Wang Zongrui , Yu Fei , Chen Wangqiao , Wang Jianfeng , Liu Jinyu , Yao Changjiang , Zhao Jianfeng , Dong Huanli , Hu Wenping , Zhang Qichun 
Published: July 2020

AbstractA practicable strategy to rationally obtain the reversible mechanochromic luminescent (MCL) material with high‐contrast ratio (green versus red) has been established. By introducing a volatile third party (small‐sized solvent molecules) into the lattice of charge transfer (CT) cocrystal of mixed‐stacking 1:1 coronene (Cor.) and napthalenetetracarboxylic diimide (NDI), a noteworthy reconfigurable molecular assembly is ingeniously achieved owing to the loosely packing arrangement as well as weakened intermolecular interactions. Accordingly, the CT excited state, strongly corresponding to the molecular stacking modes, can be intentionally tailored through external stimulus (heating, grinding, or solvent), accompanying distinct changes in photophysical properties. Subsequently, a high‐contrast reversible MCL with highly sensitive and good reproducibility is realized and the underlying mechanism is thoroughly revealed.
A Dipeptide‐Based Hierarchical Nanoarchitecture with Enhanced Catalytic Activity
Authors: Wang Chenlei , Fei Jinbo , Wang Keqing , Li Junbai 
Published: July 2020

AbstractAchieving synthetic architectures with simple structures and robust biomimetic catalytic activities remains a great challenge. Herein, we explore a facile supramolecular assembly approach to construct a dipeptide‐based hierarchical nanoarchitecture with enhanced enzyme‐like catalytic activity. In this nanoarchitecture, nanospheres are put in a chain‐like arrangement through coordination‐driven directional self‐assembly. The reversible transformation of anisotropic nanochains to isotropic nanospheres switches biomimetic activity. Notably, the assembled nanoarchitecture exhibits a high enzyme‐like activity and remarkable long‐term stability to promote hydroquinone oxidation, superior to the natural counterpart. This work will pave the way to develop reversible and reusable supramolecular biocatalysts with ordered hierarchical structures for accelerating chemical transformations.
Ligand‐Regulated Regiodivergent Hydrosilylation of Isoprene under Iron Catalysis
Authors: Kuai Chang‐Sheng , Ji Ding‐Wei , Zhao Chao‐Yang , Liu Heng , Hu Yan‐Cheng , Chen Qing‐An 
Published: July 2020

AbstractA method for the regiodivergent and stereoselective hydrosilylation of the basic industrial feedstock isoprene with unactivated silanes has been developed using earth‐abundant iron catalysts. The manipulation of regioselectivity relies on fine modification of the coordination geometry of the iron center. While a bidentate pyridine imine ligand promoted the formation of allylic silanes through 4,1‐addition, selectivity for the 3,4‐adduct homoallylic silanes was observed with a tridentate nitrogen ligand. Experimental studies and analysis were carried out to elucidate the reaction mechanism and the factors enabling manipulation of the regioselectivity. This study contributes to the art of regioselectivity control in alkene hydrofunctionalization.
Natural Soft/Rigid Superlattices as Anodes for High‐Performance Lithium‐Ion Batteries
Authors: Bai Wei , Gao Jingyu , Li Kun , Wang Gongrui , Zhou Tengfei , Li Pengju , Qin Shengyong , Zhang Genqiang , Guo Zaiping , Xiao Chong , Xie Yi 
Published: July 2020

AbstractVolume expansion and poor conductivity are two major obstacles that hinder the pursuit of the lithium‐ion batteries with long cycling life and high power density. Herein, we highlight a misfit compound PbNbS3 with a soft/rigid superlattice structure, confirmed by scanning tunneling microscopy and electrochemical characterization, as a promising anode material for high performance lithium‐ion batteries with optimized capacity, stability, and conductivity. The soft PbS sublayers primarily react with lithium, endowing capacity and preventing decomposition of the superlattice structure, while the rigid NbS2 sublayers support the skeleton and enhance the migration of electrons and lithium ions, as a result leading to a specific capacity of 710 mAh g−1 at 100 mA g−1, which is 1.6 times of NbS2 and 3.9 times of PbS. Our finding reveals the competitive strategy of soft/rigid structure in lithium‐ion batteries and broadens the horizons of single‐phase anode material design.
Species‐specific distribution model may be not enough: The case study of bottlenose dolphin (Tursiops truncatus) habitat distribution in Pelagos Sanctuary
Authors: Vassallo Paolo , Marini Chiara , Paoli Chiara , Bellingeri Michela , Dhermain Frank , Nuti Silvio , Airoldi Sabina , Bonelli Patrizia , laran Sophie , Santoni Marie C. , Gnone Guido 
Published: July 2020

Abstract

Geospatial models are used to predict the distribution of terrestrial and marine species, according to their ecological and ethological habits. The bottlenose dolphin is a cosmopolitan marine top predator, inhabiting most of the ocean, with the exception of polar and subpolar waters. This wide distribution is associated with a remarkable plasticity in ecological and behavioural habits, which makes it difficult to model and predict its distribution.
This study proposes a ‘multi‐type approach’ to predict the presence and distribution of the bottlenose dolphin in the Pelagos Sanctuary, a Specially Protected Area of Mediterranean Importance located in the north‐west Mediterranean Sea. A multi‐type model based on random forest regression was developed, analysing the distribution habits of two geographical units living in the Pelagos area.
When compared with a classical single‐type model, the multi‐type model performed much better in a prediction test (true skill statistics, TSS = 85% vs. 52%), confirming the value of this experimental approach. This work suggests that wild species should not be considered as one single‐type entity, as local specialization may change and shape their distribution habits.
Adipose stem cell‐derived extracellular matrix represents a promising biomaterial by inducing spontaneous formation of prevascular‐like structures by mvECs
Authors: Nellinger Svenja , Schmidt Isabelle , Heine Simon , Volz Ann‐Cathrin , Kluger Petra J. 
Published: July 2020

AbstractTissue constructs of physiologically relevant scale require a vascular system to maintain cell viability. However, in vitro vascularization of engineered tissues is still a major challenge. Successful approaches are based on a feeder layer (FL) to support vascularization. Here, we investigated whether the supporting effect on the self‐assembled formation of prevascular‐like structures by microvascular endothelial cells (mvECs) originates from the FL itself or from its extracellular matrix (ECM). Therefore, we compared the influence of ECM, either derived from adipose‐derived stem cells (ASCs) or adipogenically differentiated ASCs, with the classical cell‐based FL. All cell‐derived ECM (cdECM) substrates enabled mvEC growth with high viability. Prevascular‐like structures were visualized by immunofluorescence staining of endothelial surface protein CD31 and could be observed on all cdECM and FL substrates but not on control substrate collagen I. On adipogenically differentiated ECM, longer and higher branched structures could be found compared with stem cell cdECM. An increased concentration of proangiogenic factors was found in cdECM substrates and FL approaches compared with controls. Finally, the expression of proteins associated with tube formation (E‐selectin and thrombomodulin) was confirmed. These results highlight cdECM as promising biomaterial for adipose tissue engineering by inducing the spontaneous formation of prevascular‐like structures by mvECs.
Turning motivation into action: A strategic orientation model for green supply chain management
Authors: Liu Shumin , Eweje Gabriel , He Qile , Lin Zhibin 
Published: July 2020

AbstractThis study examines the key motivations for a firm to adopt a green supply chain management (GSCM) strategic orientation and the mechanisms that subsequently influence GSCM practices. Three components of GSCM orientation were examined, that is, strategic emphasis, management support and resource commitment. Data were collected from a sample of 296 manufacturing firms in China. The results indicate that the most important motivation is environmental concern, followed by customer requirements, cost saving, and competitive pressure, whereas legal requirements were not a significant factor. The results confirm that strategic orientation plays a mediating role between motivations and the actual practices. Within the three components of strategic orientation, resource commitment and strategic emphasis have a stronger direct impact on practices, whereas the effect of management support on GSCM practices is indirect through resource commitment. This study contributes to the literature by clarifying the key role of strategic orientation in turning GSCM motivations into actions.
Exosome‐mediated delivery of miR‐204‐5p inhibits tumor growth and chemoresistance
Authors: Yao Surui , Yin Yuan , Jin Guoying , Li Dan , Li Min , Hu Yaling , Feng Yuyang , Liu Yuhang , Bian Zehua , Wang Xue , Mao Yong , Zhang Jia , Wu Zhimeng , Huang Zhaohui 
Published: July 2020

AbstractBackgroundNano‐sized extracellular vesicles secreted by cells play key roles in intercellular crosstalk, and appear to be an excellent biocompatible material as therapeutic cargoes in vivo. Previously, we have demonstrated that miR‐204‐5p is a key tumor suppressor that could inhibit tumor growth, metastasis and chemoresistance.MethodsA HEK293T cell line stably expressing miR‐204‐5p (293T‐miR‐204) was constructed by lentivirus transduction. Fluorescence real‐time quantitative PCR (qPCR) was applied to measure the expression of miR‐204‐5p. CCK‐8 and colony formation assays were used to evaluate the in vitro anticancer effects, and the flow cytometry was used to detect apoptosis. The in vivo therapeutic effects of exosomal miR‐204‐5p were evaluated using a xenograft mouse model. Western blots were used to detect the protein levels of CD63, Flotillin‐2, RAB22A and Bcl2. The protein levels of RAB22A and Bcl2 in tumor tissues were measured by immunohistochemistry staining.ResultsMiR‐204‐5p was clearly upregulated in CRC cells after coculturing with 293T‐miR‐204 cell‐derived conditioned medium (CM) or exosomes. CCK‐8 and colony formation assays showed that the cell proliferation ability of CRC cells was clearly inhibited by 293T‐miR‐204 cell‐derived CM or exosomes. The inhibitory effects of exosomal miR‐204‐5p on cell proliferation were further confirmed in other types of cancers. Exosomal miR‐204‐5p could induce apoptosis and increase the sensitivity of cancer cells to the chemotherapeutic drug—5‐fluorourcil. In addition, exosomal miR‐204‐5p inhibited the tumor growth in mice. Western blot assay and IHC staining showed that the protein levels of miR‐204‐5p targets were clearly decreased in cancer cells or xenograft tissues treated with exosomal miR‐204‐5p.ConclusionsIn this study, we confirmed that exosomal miR‐204‐5p could efficiently inhibit cancer cell proliferation, induce apoptosis and increase chemosensitivity by specifically suppressing the target genes of miR‐204‐5p in human cancer cells.
The construction of emotional experience: State‐related emotional awareness and its application to psychotherapy research and practice
Authors: Lane Richard D. 
Published: July 2020

AbstractThe cognitive–developmental theory of ‘levels of emotional awareness’ (LEA) addresses an individual's capacity to experience and express emotion, a capacity highly relevant to psychotherapy. Previous papers on LEA and psychotherapy addressed the aspect of LEA theory pertaining to the ‘trait’ (i.e. enduring) aspects of an individual's emotional functioning over time. LEA theory also applies to the construction of emotional experience at any given moment, in which levels emerge or disappear in a process of microgenetic construction as a function of arousal and other variables. This state‐related perspective is supported by recent research showing that people vary in their LEA from moment to moment. Momentary changes in LEA correspond to the variations in lived experience that occur in relationships, including the therapy relationship, and provide the context for corrective emotional experiences that promote change. In this paper, the construction of emotional experience at different levels of organisation is discussed separately in relation to clients and therapists. Key phenomena relevant to psychotherapy include the transition from bodily sensations to specific differentiated emotional feelings, the ability to be aware of multiple feelings that may be contradictory or counter‐intuitive, and the appreciation of how complex combinations of feelings may differ in self and other. This perspective adds to the literature on how the integration of emotion and cognition contributes to change in psychotherapy. The clinical and research implications of this perspective are discussed.
A Six‐Coordinate Silicon Dihydride Embedded in a Porphyrin: Enhanced Hydride‐Donor Properties and the Catalyst‐Free Hydrosilylation of CO2
Authors: Ishida Shintaro , Hatakeyama Takuroh , Nomura Takuya , Matsumoto Maiko , Yoshimura Kimio , Kyushin Soichiro , Iwamoto Takeaki 
Published: July 2020

AbstractThe catalyst‐free hydrosilylation of CO2 under mild conditions remains limited. Herein, we report the synthesis, characterization, and reactivity of 5,10,15,20‐tetraphenylporphyrinato(dihydrido)silicon(IV) (1) as a six‐coordinate silicon dihydride. The Si‐H moiety of 1 reacts with polar double bonds and CO2 in the absence of a catalyst to afford hydrosilylated products. Combining the hydrosilylation with subsequent transformation furnishes formic acid from CO2. Computational studies indicate that the hydride‐donor properties of 1 are exceptionally high for a neutral silicon hydride, and that the direct hydride transfer from silicon to carbon is a pivotal step in the hydrosilylation of CO2 with 1.
Exceptionally Plastic/Elastic Organic Crystals of a Naphthalidenimine‐Boron Complex Show Flexible Optical Waveguide Properties
Authors: Naim Khalid , Singh Manjeet , Sharma Sachin , Nair Rajesh V. , Venugopalan Paloth , Chandra Sahoo Subash , Neelakandan Prakash P. 
Published: July 2020

AbstractThe design of molecular compounds that exhibit flexibility is an emerging area of research. Although a fair amount of success has been achieved in the design of plastic or elastic crystals, realizing multidimensional plastic and elastic bending remains challenging. We report herein a naphthalidenimine–boron complex that showed size‐dependent dual mechanical bending behavior whereas its parent Schiff base was brittle. Detailed crystallographic and spectroscopic analysis revealed the importance of boron in imparting the interesting mechanical properties. Furthermore, the luminescence of the molecule was turned‐on subsequent to boron complexation, thereby allowing it to be explored for multimode optical waveguide applications. Our in‐depth study of the size‐dependent plastic and elastic bending of the crystals thus provides important insights in molecular engineering and could act as a platform for the development of future smart flexible materials for optoelectronic applications.
Propyne Gas Adsorption in a Cyclic Hexapeptoid: A Combined In Situ XRPD and DFTB Study**
Authors: Pierri Giovanni , Landi Alessandro , Macedi Eleonora , Izzo Irene , De Riccardis Francesco , Dinnebier Robert E. , Tedesco Consiglia 
Published: July 2020

AbstractCyclic peptoids are macrocyclic N‐substituted oligoglycines, with remarkable structural, chemical and physical properties. The gas adsorption properties of a permanently porous hexameric cyclopeptoid decorated with four propargyl and two methoxyethyl side chains were monitored by in situ X‐ray powder diffraction (XRPD). High‐resolution XRPD data together with Rietveld and density functional based tight binding (DFTB) method allowed us to locate propyne guest molecules inside the host channels, even though the powder sample contains more than one phase. We were able to characterize the host‐guest interactions, providing useful information on the host recognition sites and discuss host adaptiveness and host–guest chemical affinity in comparison with analogous compounds.
ACC.20: Impact of social media at the virtual scientific sessions during the COVID‐19 pandemic
Authors: Mackenzie Graham , Gulati Martha 
Published: July 2020

AbstractBackgroundThe COVID‐19 pandemic led to the American College of Cardiology (ACC) Annual Scientific Session 2020 (ACC.20) being held as a virtual event.HypothesisSocial media activity around a virtual event might be quite different to that of a physical meeting. The goal of this study was to assess impact of ACC.20 through Twitter and compare it to ACC.19.MethodsData were extracted using NodeXL, with analysis in Excel.ResultsACC.20‐related tweeting was demonstrated globally. However tweeting and participants fell substantially for ACC.20. Tweeting, participation and tweet views were overestimated by the most widely used social media analysis tool used at medical conferences (Symplur).ConclusionComparing the 2019 and 2020 Scientific Sessions, the global cardiology community continued to communicate despite COVID‐19, but with reduced social media activity potentially due to the briefer format, no physical interaction and private virtual chatroom during live sessions, reducing visibility of new cardiology research findings.
Long‐term antithrombotic management patterns in Asian patients with acute coronary syndrome: 2‐year observations from the EPICOR Asia study
Authors: Zheng Bo , Huo Yong , Lee Stephen W.‐L. , Sawhney Jitendra P. S. , Kim Hyo‐Soo , Krittayaphong Rungroj , Pocock Stuart J. , Nhan Vo T. , Alonso Garcia Angeles , Chin Chee Tang , Jiang Jie , Jan Stephen , Vega Ana Maria , Hayashi Nobuya , Ong Tiong K. 
Published: July 2020

AbstractBackgroundDespite guideline recommendations, dual antiplatelet therapy (DAPT) is frequently used for longer than 1 year after an acute coronary syndrome (ACS) event. In Asia, information on antithrombotic management patterns (AMPs), including DAPT post discharge, is sparse. This analysis evaluated real‐world AMPs up to 2 years post discharge for ACS.HypothesisThere is wide variability in AMP use for ACS management in Asia.MethodsEPICOR Asia (NCT01361386) is a prospective observational study of patients discharged after hospitalization for an ACS in eight countries/regions in Asia, followed up for 2 years. Here, we describe AMPs used and present an exploratory analysis of characteristics and outcomes in patients who received DAPT for ≤12 months post discharge compared with >12 months.ResultsData were available for 12 922 patients; of 11 639 patients discharged on DAPT, 2364 (20.3%) received DAPT for ≤12 months and 9275 (79.7%) for >12 months, with approximately 60% still on DAPT at 2 years. Patients who received DAPT for >12 months were more likely to be younger, obese, lower Killip class, resident in India (vs China), and to have received invasive reperfusion. Clinical event rates during year 2 of follow‐up were lower in patients with DAPT >12 vs ≤12 months, but no causal association can be implied in this non‐randomized study.ConclusionsMost ACS patients remained on DAPT up to 1 year, in accordance with current guidelines, and over half remained on DAPT at 2 years post discharge. Patients not on DAPT at 12 months are a higher risk group requiring careful monitoring.
Addition of Phosphorus and Nitrogen Support the Invasiveness of Alternanthera Philoxeroides Under Water Stress
Authors: Sun Jianfan , Javed Qaiser , Azeem Ahmad , Ullah Muhammad Saif , Rasool Ghulam , Du Daolin 
Published: July 2020

AbstractCoordination of plant functional traits with changes in the environment is helpful to understand the mechanisms underlying both invasiveness and adaptation of plants. Thus, to investigate the performance and functional traits in invasive Alternanthera philoxeroides (Mart.), an experiment of water stress is conducted with different nutrient concentrations. Alternanthera philoxeroides plants are grown under natural and nutrient soils and subjected to three levels of nitrogen (N) and phosphorus (P) solution: ambient P and N concentration (P−N−), P addition with an ambient N concentration (P+N−), and P addition with high N concentration (P+N+) in combination with three different irrigation water levels as 1) 100% irrigation, 2) 50% irrigation, and 3) 25% deficit irrigation. Based on results, A. philoxeroides produces significantly higher biomass in both soils under 100% irrigation with P+N− treatment and exhibits higher values of leaf area and root length. However, 25% irrigation with P−N− treatment in both soils exerts a significant negative effect on relative growth rate and root/shoot ratio of A. philoxeroides plants. Under 50% irrigation in soils with both P+N− and P+N+ treatments, high values of leaf nitrogen are recorded. Moreover, nutrient soil is more supportive to A. philoxeroides than natural soil.