bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preliminary study of calcium homeostasis modulator 1 involved in trigeminal neuralgia
Authors: Liu Yi , Li Keji , Huang Dong , Yan Xuebin 
Published: March 2020

Abstract
Background: The aim of this study was to observe the changes in the expression of calcium homeostasis modulator 1 (CALHM1) in the trigeminal nucleus of the trigeminal neuralgia (TN) rats with the infraorbital nerve-chronic constrictive nerve injury (ION-CCI) and to explore the role of CALHM1 in TN.Methods: Thirty SD rats were randomly assigned to 5 groups, namely normal control group (Control group), sham operation group (Sham group), TN model group (ION-CCI group), ruthenium red treatment group (RuR group) and control group of ruthenium red (NS group), with 6 rats in each group. An animal model was established by loosely ligating the rat's infraorbital nerve with a chrome gut in the ION-CCI group, while mice in the sham group were only exposed to the nerve and did not receive ligature. The rats in the RuR group were intraperitoneally injected with 0.5 mg/kg of CALHM1 inhibitor ruthenium red on the 9th day after the infraorbital nerve ligation, while the rats in NS group were intraperitoneally injected with an equal volume of normal saline on the 9th day after surgery. All experimental rats were tested for pain behavior 1 day before surgery, 1, 3, 5, 7, 9, 11 and 14 days after surgery, including the mechanical pain threshold of VonFrey filament in the trigeminal innervated skin area and number of faces captured in video recording. The expression of CALHM1 in the trigeminal spinal nucleus was detected on the 15th day after operation in all experimental groups.Results: The expression of CALHM1 in the trigeminal spinal nucleus of the ION-CCI group was significantly higher than that of control group and sham group on the 3rd and 15th day after modeling. The intraperitoneal injection of CALHM1 inhibitor ruthenium red increased the mechanical pain threshold of ION-CCI rats and significantly reduced the number of scratches, but did not change the expression of CALHM1 in the trigeminal spinal nucleus.Conclusion: The expression of CALHM1 protein in the trigeminal spinal nucleus is involved in the central sensitization of TN pain, which can be induced by elevated expression. Moreover, the hyperalgesia can be improved by using CALHM1 inhibitor.
With versus Without Primary Tumor Radiotherapy in Patients with Unresectable Stage IV Rectal or Rectosigmoid Cancer: A Propensity Score Matching Analysis for Survival
Authors: Wang Gang , Wang Ling Wen , Jin Jie Hai , Dong min Hong , Chen wei Wei , Li kai Xiao , Li dong Guo , Li lei Lei 
Published: March 2020

Abstract
Background: To evaluate the impact of primary tumor radiotherapy on survival in patients with unresectable metastatic rectal or rectosigmoid cancer. Methods: Form September 2008 to September 2017, 350 patients with unresectable metastatic rectal or rectosigmoid cancer were retrospectively reviewed in our center. All patients received at least 4 cycles of chemotherapy, and were divided into two groups according to with primary tumor radiotherapy or without. 163 patients received primary tumor radiotherapy, and the median radiation dose was 56.69Gy(50.4-60). Survival curves were estimated from the Kaplan–Meier procedure to roughly compare survival among two groups. Subsequently, 18-month survival was used as the outcome variable for this study. This study mainly evaluated the impact of primary tumor radiotherapy on survival of these patients through a series of multivariate Cox regression analyses after propensity score matching (PSM). Results: The median follow-up time was 21 months. All 350 patients received a median of 7 cycles of chemotherapy (range 4-12), 163 (46.67%) patients received primary tumor radiotherapy for local symptoms. The Kaplan–Meier survival curves showed a significant overall survival (OS) advantage for primary tumor radiotherapy group to without radiotherapy (20.07 vs 17.33 months; P=0.002). In this study, multivariate Cox regression analysis after adjusted covariates, multivariate Cox regression analysis after PSM, and inverse probability of treatment weighting (IPTW) analysis and propensity score (PS)-adjusted model analysis consistently showed that primary tumor radiotherapy could effectively reduce the risk of death for these patients at 18 months (HR: 0.62, 95% CI 0.40-0.98; HR:0.79, 95% CI:0.93-1.45; HR: 0.70, 95% CI 0.55-0.99 and HR: 0.74, 95% CI:0.59-0.94). Conclusion: Compared with patients with stage IV rectal or rectosigmoid cancer who did not receive primary tumor radiotherapy, received primary tumor radiotherapy reduced the risk of death in these patients. The radical doses（59.4Gy/ 33 fractions or 60Gy/ 30 fractions） of radiation for primary tumors might be considered for unresectable metastatic rectal or rectosigmoid cancer, not just for relieve symptoms. Keywords: Stage IV Rectal cancer, primary tumor radiotherapy, propensity score matching.
Imaging features of evolving COVID-19 infection on computed tomography: Initial experience in Zhuhai, China.
Authors: Zhang Yaqin , Pang Pengfei , Ma Han , Chen Binghui , Li Yingqin , Jiang Guanmin , Cai Zeyu , Qin Yujuan , Chughtai Aamer , Shan Hong 
Published: March 2020

Abstract
Objectives To retrospectively analyze the most common imaging features on CT at baseline and as they evolve with time as the disease progresses or resolves in a cohort of patients affected with 2019 coronal virus disease (COVID-19) pneumonia in Zhuhai, China.Methods We evaluated 38 patients with COVID-19 in the authors’ institution from Jan 1 to Jan 31, 2020. Cases were confirmed by real-time RT-PCR and were analyzed for epidemiological, demographic, clinical, and radiological features. Outcomes were followed up until Feb 18, 2020. Results 38 initial scans and 62 follow-up scans were obtained. 28 (74%) patients had the history of travel to or residence in Hubei Province of China in 14 days prior to the illness onset. Common findings included ground-glass opacification (GGO), sometimes mixed with consolidation, and interlobular septal and intralobular interstitial thickening. Follow-up imaging often demonstrated peripheral GGO and consolidations spreading to the remainder of the lungs and the increasing consolidative component reflecting the progression of the disease. 8 patients (21%) whose swabs or serum were positive for COVID-19 had no imaging findings on CT throughout the disease course. After treatment the serum and sputum tests became negative for COVID-19 in 32(84%) cases. 28(74%) patients were discharged and three (8%) of them were transferred to the Observation Ward, while seven (18%) patients were kept in Isolation Ward. Conclusion The commonest pattern observed was GGO alone or GGO mixed with consolidation predominantly in lower and peripheral lungs. The follow-up CT scan is crucial for the diagnosis and evaluation of the disease process.
Analysis of hybrid demand pattern on a water distribution network with transition from intermittent to continuous water supply in Riberas de Sacramento, Chihuahua
Authors: David Carlos , García Mendoza , Navarro Gómez Carmen Julia 
Published: March 2020

Abstract
This paper establishes a methodology to characterize the experiment design and analyze the hybrid demand pattern for a water distribution network in transition from intermittent to continuous supply and thus have a basis for the definition of a management model that defines adequate operation of a water distribution network for a sector based on the demand and the type of supply available. An analysis of the water supply situation during transition from intermittent to continuous supply in a referent sector called Riberas de Sacramento was carried out on the behavior of the network, the operating criteria of the system and the demand of the sector. For the consumption analysis, three consecutive years of data collected by government institution from micro meters were analyzed. In order to characterize the hybrid demand pattern to operate the network, prior site analysis determined the minimum amounts of pressures and consumption records to obtain series of data for analysis. After the review of the transition from intermittent to continuous water supply and the establishment of methodology to characterize the hybrid demand pattern, the need for a hybrid demand pattern is required, and this experiment design gives part to achieve it.
Salt Intake from Traditional Breads: A Public Health Challenge for Decreasing Non-communicable Diseases in Iran
Authors: Hadian Zahra , Feizollahi Ehsan , Khosravi Kianoosh , Mofid Vahid , Rasekhi Hamid 
Published: March 2020

Background:
In recent decades, a decrease of sodium chloride (NaCl) salt in diets such as
breads has raised public attention for control of non-communicable diseases (NCDs) in developed
and developing countries. Bread is an important food in public diets in Iran as well as many other
countries.

Aim:
The aim of this study was to assess salt (NaCl) content of the Iranian traditional breads and to
estimate daily salt intake through consumption of these foodstuffs. The study was carried out in five
major cities of Iran in 2016.

Methods:
In total, 237 traditional bread samples (including Sangak, Taftoon, Lavash and Barbari)
were collected and the sample NaCl content was assessed using published methods by the International
Organization for Standardization (ISO) and Association of Official Analytical Chemists
(AOAC). Values were compared to Iranian standard limit values.

Results:
Salt content of the traditional breads ranged from 0.03 g to 2.99 g per 100 g of dry weight
(D.W.). Overall, 49.2% of the traditional bread samples in Tehran and 47.2% of the traditional bread
samples in other cities exceeded the standard limit. Since 93.8% of Sangak breads from Tehran met
the salt limit criteria of national standards, this traditional bread includes a more favorable nutritional
status compared to that other breads do.

Conclusion:
Awareness of salt level in breads and monitoring salt use in bakeries can help update
food policies and improve public lifestyle. A decrease in the ratio of salt is recommended as the major
nutritional intervention for the prevention and control of NCDs.
Laparoscopic approach for huge benign ovarian cyst in woman with history of previous 5 laparotomies (including 4 cesarean section)
Authors: Taraby Aisha Ebrahim , Zamreek Ayman , Alyawer Nahla , Alsudairy Saad , Boogis Dalal 
Published: March 2020

An adnexal mass (mass of the ovary, fallopian tube, or surrounding connective tissues) is a common gynecologic problem. In the United States, it is estimated that there is a 5 to 10% lifetime risk for women undergoing surgery for a suspected ovarian neoplasm. Adnexal masses may be found in females of all ages, from fetuses to older adults, and there are a wide variety of types of masses. Today, the surgical treatment has become more conservative and less invasive; hence, a laparoscopic approach in the presence of benign cysts has become a golden standard. In the past, patients with previous abdominal surgery were discouraged from undergoing laparoscopic surgery because of its increased risk of bowel injury caused by needle and trocar insertion. Complications occur two times more frequently in patients with previous laparotomy in a study of long series. The potential risk for injury of organs adherent to the abdominal wall during veress needle or trocar insertion as well as the necessity for adhesiolysis and its attendant complications are the two major specific problems constraining surgeons from performing laparoscopic cystectomy/ oophorectomy for patients with previous abdominal surgery. Herein, we report a case of a 32-year-old woman P4 + 2 with history of previous four cesarean section and a following laparotomy for interval sterilization presented to our clinic with abdominal mass, discovered by ultrasound scan, managed by a laparoscopic approach.Keywords: Benign ovarian cyst, laparoscopy, ovary, previous cesarean section, previous laparotomy
A importância das atividades lúdicas na Educação Infantil
Authors: Niles Rubia Paula , Socha Kátia 
Published: March 2020

No desenvolvimento deste trabalho apresenta-se como tema a importância das atividades lúdicas na Educação Infantil, de caráter bibliográfico mostra a importância do lúdico no processo de socialização das crianças como também sua importância no processo ensino e aprendizagem, através dos jogos, dos brinquedos, das brincadeiras. Percebe-se que o lúdico está presente na construção do processo de ensino e aprendizagem na educação infantil, que é de suma importância, fazendo deste assunto um fator primordial a ser trabalhado por todos os pedagogos, professores, comunidade, escola e familiares que tenham a intenção de educar, sabendo que isto não se limita a repassar informações ou mostrar apenas um caminho, mas sim ajudar a criança a tomar consciência de si mesma, dos outros e da sociedade. Teve como objetivo geral analisar e refletir sobre a importância da brincadeira para o desenvolvimento da criança, e destacar como também é importante instrumento para a construção do conhecimento e está vinculado a uma linguagem natural, que proporciona acesso a cultura e a troca de conhecimentos num processo de amadurecimento. Portanto o brincar na Educação Infantil, tem sido objeto de estudo, sendo sempre levando em conta a grande importância que há em momentos em que as crianças brincam e assim tem o seu desenvolvimento cognitivo cada vez mais ampliado. A atividade em que em que a brincadeira está presente torna o ambiente da aprendizagem bem mais enriquecedor, pois, o ato de educar não está restrito simplesmente a um quadro de escrever e uma carteira onde o aluno fica sentado, vai muito além da transmissão de conhecimento.
Charakterystyka grup i organizacji producentów owoców, warzyw, grzybów i ziół w Polsce w aspekcie wdrażania systemów jakości
Authors: KOPIŃSKI ŁUKASZ , CZERNYSZEWICZ EUGENIA 
Published: March 2020

Uwarunkowania prawne i rynkowe sprawiają, że problematyka jakości i zarządzania jakością w ogrodnictwie jest istotna dla wszystkich uczestników rynku produktów ogrodniczych. Zapewnienie jakości owoców i warzyw jest realizowane m.in. poprzez wdrażanie systemów i standardów jakości. Celem pracy jest określenie liczby i rodzaju posiadanych certyfikatów jakościowych w grupach i organizacjach producenckich zróżnicowanych ze względu na formę prawną, liczbę członków, okres powstania, profil produkcji, położenie w kraju, kierunki sprzedaży oraz strukturę własności. Z badań wynika, że najbardziej popularnym standardem jakościowym wdrażanym i certyfikowanym w grupach i organizacjach producentów produktów ogrodniczych jest standard GlobalG.A.P.
Sok z czerwonego grejpfruta (Citrus paradisi) jako naturalna substancja ograniczająca niekorzystne zmiany jakości jaj konsumpcyjnych podczas ich przechowywania
Authors: DRABIK KAMIL , BATKOWSKA JUSTYNA , WLAZŁO ŁUKASZ , AL- SHAMMARI KARRAR I.A. , GRYZIŃSKA MAGDALENA 
Published: March 2020

Celem badań była ocena wykorzystania soku z czerwonego grejpfruta (Citrus paradisi), nanoszonego powierzchniowo na skorupy jaj kurzych w celu spowolnienia procesu ich starzenia się w trakcie przechowywania. Materiał badawczy stanowiło 300 jaj kurzych o zbliżonej masie zebranych w tym samym dniu. Jaja podzielono na 2 równoliczne grupy, tzn. kontrolną (NC), w której skorup nie poddawano żadnym zabiegom, i doświadczalną (GT), w której skorupy pokryto świeżo wyciśniętym sokiem z czerwonego grejpfruta. Jaja układano w wytłaczankach transportowych tępym końcem ku górze i przechowywano w warunkach typowych dla przechowalni (temp. 14°C, wilgotność 70%). Oceny cech jakości jaj dokonano na początku doświadczenia, a następnie po 14 i po 28 dniach. Po 28 dniach przechowywania jaja pokryte sokiem z grejpfruta charakteryzowały się istotnie (p £ 0,05) większymi: ubytkami masy, przewodnością wodną skorupy oraz jej grubością. Jednocześnie stwierdzono istotnie większą gęstość skorupy (p £ 0,05) i jej wytrzymałość (p > 0,05). W grupie jaj doświadczalnych obserwowano również istotnie (p £ 0,05) większy udział białka w masie jaja i jego wyższe pH w 14 dniu przechowywania. Sok z grejpfruta wpłynął stabilizująco na pH żółtka w czasie przechowywania jaj przez 28 dni. Wyniki doświadczenia wskazują, że zastosowanie soku z grejpfruta nieznacznie ogranicza niekorzystne zmiany jakości jaj w czasie ich przechowywania.
СМЕРНИЦЕ ЗА РАЗВОЈ КОРИСНИЧКОГ ИНТЕРФЕЈСА ЗА НАДЗОР И КОНТРОЛУ ПМИС СИСТЕМА
Authors: Станишић Душан 
Published: March 2020

У раду је разматран проблем интеракције диспечера зимског одржавања са ПМИС системом у циљу скраћења времена реаговања зимске службе. Проблем је решен применом технологија из области „интеракција човек-рачунар” и принципа системског инжењерства и инжењерства упот­ребљивости. У раду је доказана истраживачка хипотеза:
„Унапређењем корисничког интерфејса путног мете­оролошко-информационог система повећаће се ефи­касност и смањити трошкови зимског одржавања путева.“
Резултати истраживања преточени су у Смернице за развој корисничког интерфејса за надзор и контролу ПМИС система.
TEORI-TEORI ETIKA DAN SUMBANGAN PEMIKIRAN PARA FILSUF BAGI ETIKA BISNIS
Authors: Weruin Urbanus Ura 
Published: March 2020

Sebagai ilmu preskriptif, etika adalah cabang filsafat yang mempertimbangakan secara kritis tindakan mana yang baik atau tindakan mana yang buruk berdasarkan ajaran moral tertentu. Sementara ajaran moral adalah ajaran tentang kebaikan manusia berdasarkan martabat setiap orang sebagai manusia. Studi literer dengan menggunakan metode content analysis yang dilakukan terhadap berbagai sumber kepustakaan yang ada memperlihatkan bahwa terdapat dua teori utama etika yang relevan bagi etika bisnis. Pertama teori etika konsekuensialis atau teleologis. Kedua, teori etika nonkonsekuensilis Termasuk dalam teori etika konsekuensilis adalah etika utilitarianisme, etika egoism, dan etika hedonisme. Sementara teori etika non-konsekuensialis mencakup etika deontologi, etika keutamaan, dan etika kesetaraan dan keadilan sebagai kewajaran. Etika konsekuensialis menilai moralitas tindakan atau keputusan berdasarakan tujuan, kegunaan, atau dampak positif yang diperoleh dari tindakan atau keputusan tersebut. Sementara etika nonkonsekuensialis memfokuskan moralitas tidakan atau putusan pada kewajiban untuk melakukan apa yang merupakan kewajiban, pada motivasi dan karakter moral si pelaku tindakan, serta pada prinsip keadilan. Semua teori etika ini, berkontribusi bagi pemahaman terhadap etika bisnis. As a prescriptive science, ethics is a branch of philosophy that considers critically which actions are good or which actions are bad based on certain moral teachings. While moral teachings are teachings about human kindness based on the dignity of each person as a human being. Literary studies using content analysis methods conducted on various sources of existing literature show that there are two main theories of ethics that are relevant for business ethics. First the consequentialist or teleological ethical theory. Second, the theory of non-consensual ethics Included in the theory of consequent ethical ethics is the ethics of utilitarianism, ethics of egoism, and ethics of hedonism. While non-consequentialist ethical theories include deontological ethics, virtue ethics, and equality and fairness ethics as fairness. Consequentialist ethics assesses the morality of an action or decision based on the purpose, usefulness, or positive impact obtained from the action or decision. While non-consequentialist ethics focuses on the morality of actions or decisions on the obligation to do what is mandatory, on the motivation and moral character of the perpetrators of actions, as well as on the principle of justice. All of these ethical theories, contribute to understanding business ethics.
FAITH-BASED MARKETING: ANTECEDENTS OF PURCHASE INTENTION FOR HALAL-CERTIFIED PERSONAL CARE PRODUCTS
Authors: Widyanto Hanif Adinugroho , Irfanur Muhammad Khalil 
Published: March 2020

Tujuan dari penelitian ini adalah untuk menemukan faktor-faktor yang mempengaruhi minat membeli konsumen terhadap produk perawatan pribadi yang tersertifikasi halal. Faktor-faktor yang mempengaruhi niat membeli konsumen adalah religiusitas, kesadaran halal, sertifikasi halal, persepsi pribadi tentang masyarakat, dan pemasaran halal. Penelitian ini menggunakan metode survei dengan kuesioner sebagai instrumen untuk mengumpulkan data dan diberi skor menggunakan Skala Likert dan dianalisa dengan metode regresi berganda pada aplikasi SPSS 24. Penelitian ini dilakukan di wilayah Jabodetabek dengan total 309 responden. Hasil penelitian ini menunjukkan bahwa religiusitas dan kesadaran halal tidak memiliki pengaruh signifikan terhadap niat beli untuk produk perawatan pribadi bersertifikat halal. Selain itu, sertifikasi halal, persepsi pribadi dan masyarakat, dan pemasaran halal ditemukan memiliki pengaruh signifikan terhadap niat pembelian produk perawatan pribadi bersertifikat halal. Semua variabel memiliki pengaruh signifikan secara simultan terhadap niat pembelian produk perawatan pribadi bersertifikat halal. Hasil dari penelitian ini dapat memberikan masukan bagi perusahaan terkait pentingnya melakukan sertifikasi halal bagi produk perawatan pribadi yang mereka produksi agar dapat meningkatkan minat membeli konsumen, dan menentukan secara tepat strategi pemasaran mereka. The purpose of this research was to find out the factors influencing consumer’s purchase intention toward halal-certified personal care products. The factors influencing consumer’s purchase intention investigated in this study were religiosity, halal awareness, halal certification, personal societal perception, and halal marketing. This research is a quantitative research with questionnaire as the instrument to gather the data and was scored using the Likert Scale and analyzed with multiple regression on SPSS 24. This research was conducted in the Greater Jakarta area with a total of 309 respondents. The results of this research showed that religiosity and halal awareness had no significant influence toward purchase intention for halal-certified personal care products. Additionally, personal societal perception, halal certification, and halal marketing were found to have significant influences toward purchase intention of halal-certified personal care products. Finally, all the variables had simultaneously significant influence on purchase intention of halal-certified personal care products. The results of this study could provide companies with a valuable insight regarding the importance of and urgency for halal-certifying their personal care products to improve customer’s purchase intention, and to set their marketing strategy accordingly.
Agricultural Development in Thailand: Experience and Implications for Vietnam
Authors: Ngoc Vinh Bao 
Published: March 2020

Agriculture in Thailand has developed as it is today because of the long-term strategic vision of the government. Since the 1980s, agricultural development policy has used a variety of marketing principles, which ensures that there is aharmonious development with rural areas. Agricultural development policies in Thailand faced a lot of challenges such as the narrowed farming area, a large number of rural labor force moving to urban, farmers getting no benefits from government policies.
The research shed light on agricultural development policies in Thailand, especially key points in agricultural extension policies, agricultural support, rural industrialization policies, modern scientific applications, foreign investment in agriculture, and then drawing some policies in sustainable agriculture development in our country.
Managing social work according to the educational philosophy of Ho Chi Minh City University of Technology and Education
Authors: Thuy Nguyen Thi Nhu 
Published: March 2020

This article helps administrators, social workers to see the reality and difficulties in organizing, managing and implementing social activities for students at the Ho Chi Minh City University of Technical and Education - a school that does not specialize in social work, but there are diverse and diversified community-oriented activities.