bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design and Development of Calculation System for Normalized Difference in Vegetation Index (NDVI) Using Landsat 8 Satellite Image
Authors: Sunardi  , Fadlil Abdul , Laspandi Jamaludin Dwi 
Published: November 2019

Abstract
The satellite image is a Earth’s surface image recorder that is performed without physical contact with the object. Satellite imagery can also be used as a solution to get the information of a wide area that is covered by vegetation. Normalized Difference Vegetation Index (NDVI) is an index depicting the level of a green plant with a combined tally of the Visible Red Band and the Near Infrared Band. Visible Red Band is the band of Landsat satellite image 8 whereas Near Infrared Band is a band 5 of Landsat satellite image 8. This research intends to build a system of counting of NDVI data by making use of satellite images Landsat 8 on the special region of Yogyakarta. The equation used in this study is the equation correction between Visible Red Band and Near Infrared Band from Landsat 8 satellite imagery and NDVI equation. Zoom functions and masking is also built into the system so it can be more focused on the area that wants to the canvas. The results of this research are in the form of value and a map of the NDVI that have been colors segmented in the Province of Yogyakarta.
Kelakai Extract Protects Skin From UV-Induced Oxidative Damage
Authors: Mashuri M , Sihombing L D M , Alfaqihah S , Edyson E , Suhartono E 
Published: November 2019

Abstract
Oxidative stress is an unbalance situation between oxidant and antioxidant. Oxidative stress can be caused by UV exposure until it can result skin damage. This damage caused by the production of reactive oxygen compound (ROC), such as excessive superoxide anion. Thus, natural exogen antioxidant is needed, that is Kelakai. This research is pure experimental research with rats (Rattus norvegicus) as its subject. There were 24 samples were divided into 4 treatment groups; samples were chosen used simple random sampling method and repetition value used Federe method. Kelakai leaves were extracted using ethanol with maseration method. Superoxide anion level and superoxide dismutase enzyme activities were measured with Misra and Fridovich method; carbonyl level was measured using modified DNPH (dinitro phenilhidrazin) method; and conjugated diena level was measured with Kwiat Kowska method. The data was analysed statistically, and resulted significant differences between the group that only exposed to UV and the group that was given Kelakai extract and exposed to UV. Based on that result, it can be concluded that Kelakai extract can influence superoxide dismutase activities, superoxide anion level, carbonyl level, and conjugated diena in rats skin exposed to UV.
Anti-diabetic properties of root extracts of Ruellia tuberosa L: effects on serum enzyme activity
Authors: Safitri A , Roosdiana A , Arrochmah N , Nur’Adya S S 
Published: November 2019

Abstract
This study aims to determine the anti-diabetic properties of the root extracts of Ruellia tuberosa L to enzymes (amylase, protease, and lipase) activities in serum of diabetic rats. Rats were divided into five groups: control, diabetic, and treatment groups with doses of 250, 375, and 500 mg/kg body weights. All treatment groups received root extracts of R. tuberosa L for 21 days by oral administration. Results from LC-MS study revealed that the flavonoids compounds including sorbifolin, cirsimaritin, cirsimarin, and cirsiliol 4’-glucoside, were detected in the extracts. The animal study results showed decreases in blood glucose levels by 54.56%, 37.70%, and 16.79%, for treatment doses of 250, 375, and 500 mg/kg body weights, respectively. All enzymes activities increased in diabetic rats, and after treatment the enzyme activities decreased. The decreases in protease activity were 52%, 36%, and 20% for doses of 250, 375, and 500 mg/kg body weights, respectively. In addition, the amylase and lipase activities also showed similar trends with decreasing activities to 63% and 51%, 42% and 37%, 16% and 21%, for treatment doses of 250, 375, and 500 mg/kg body weights, respectively.
Anti-inflammatory Activity of Quercitrin on Hypoxia-induced EA.hy926
Authors: Ginting C N , Lister I N E , Girsang E , Mutia M S , Lubis Y E P , Amalia A , Rizal R , Widowati W 
Published: November 2019

Abstract
The evidence support the existence of oxygen deprivation involved in pregnancy disorder or preeclampsia. The intensive hypoxia also regulates production of placental pro-inflammatory cytokines. Quercitrin belongs to flavonoid group is known to have antioxidant and anti-inflammatory activity. This study aims to determine the potential of Quercitrin as anti-inflammatory in hypoxia-induced EA.hy926 as preeclampsia model. The cytotoxic assay of Quercitrin against EA.hy926 was conducted using MTS (3-4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium). The data were analyzed using SPSS ver 20.0 software. One-way analysis of variance (ANOVA) was conducted, followed Tukey HSD post-hoc test and p<0.05 was considered to be significant. The anti-inflammatory potential of Quercitrin (25 and 6.25 μg/ml) toward hypoxia-induced EA.hy926 was determined using ELISA to measure IL-10 and TNF-α. Quercitrin (3.13 - 25 μg/ml) were nontoxic to the EA.hy926 cells. Quercitrin (25 and 6.25 μg/ml) were capable to reduce TNF-α compared to positive control (2% O2 hypoxia-induced cells) but no significant increase in IL-10. Our study suggests that quercitrin possess anti-inflammatory properties through suppression of TNF-α in hypoxia-induced EA.hy926 cells.
Effect of DHA Supplementation on The MDA and SOD Levels in Protein Malnourished Rats
Authors: Sanyoto D D , Asnawati A , Triawanti T 
Published: November 2019

Abstract
Protein malnutrition interferes with the synthesis of enzymes served as antioxidants while reducing antioxidants concentration in tissues, leading to oxidative stress. One of the most stable markers of oxidative stress is malondialdehyde (MDA). Docosahexaenoic acid (DHA) has an important role in inhibiting oxidative stress and protecting the tissue from peroxidative damage to lipids and proteins, thereby reducing oxidative stress in the tissue. This study aimed to analyze the effect of DHA on the MDA and superoxide dismutase (SOD) levels in protein malnourished rats. This study was carried out using the rat model Rattus norvegicus. After delivery, the rats were classified into two groups, namely, the malnutrition group (MG) and the non-malnutrition group (NMG). The MG was given low-protein diet since birth until 50 days old. The MG was further classified into two subgroups, namely the control malnutrition group with normal feed recovery (CMG), and the treated malnutrition group with normal feed recovery and DHA supplementation for 6 weeks (TMG). At the end of treatment, the blood MDA and SOD levels were assessed. The results showed that the MDA levels in the NMG, CMG, and TMG were 812.75 μM, 647.75 μM, and 624.00 μM respectively. The SOD levels were 19.40 μM, 19.20 μM, and 26.80 μM, respectively. The Kruskal Wallis test showed a significant difference in MDA levels between groups (p = 0.001). The posthoc test using the Mann Whitney test showed that the MDA level in TMG was significantly different from that in NMG, but not significantly different from CMG. The Anova test showed a significant difference in SOD levels between groups (p = 0.000). The Tukey posthoc test showed that the SOD level in TMG was significantly different from that in NMG and CMG. DHA has been shown to play an antioxidant role in malnutrition. DHA can increase the levels of SOD enzymes so that oxidative stress that occurs in malnutrition can be reduced. This is proven by the decrease in MDA levels as a lipid peroxidation product. It can be concluded that DHA supplementation can reduce the MDA levels and increase the SOD levels in protein malnourished rats.
The Effect of High Fat High Fructose Diet (Modification of AIN-93M) on Nuclear Factor Kappa Beta Expression in the Liver Tissue of Male Sprague Dawley Rats
Authors: Engel M M S , Kusumastuty I , Anita K W , Handayani D 
Published: November 2019

Abstract
Metabolic inflammation (low-grade inflammation) remains an etiopathogenic key factor in the development of metabolic syndrome. Nuclear Factor Kappa Beta (NF-κβ) is a transcription regulator of genes having a role in immunity, the inflammatory response which can be associated with obesity-related pathological conditions like nonalcoholic fatty liver (NAFLD). Various stimuli, such as metabolic stress (hyperglycemia, ROS, fat metabolism) and proinflammatory cytokines (TNF-α, IL-6, IL-1β) could activate NF-κβ. This study was aimed to investigate the underlying molecular mechanisms of NAFLD in rats fed a modified AIN-93M HFHF (High Fat High Fructose) diet. The design of this study was experimental post-test only controlled group design. Thirty male Sprague Dawley rats were distributed into 2 treatment groups by a completely randomized design (CRD) technique. The sacrifice was performed after 17 weeks of treatment. NF-κβ expression was assessed by an immunohistochemical method (IRS score). The results showed there were significant differences in feed intake and energy intake between groups P1 and P2 (p = 0,000, p = 0,000). The average NF-κβ expression in the P2 group was significantly higher (p = 0.000) compared to the control group (P1). The correlation test between dietary intake and NF-κβ expression proved that there was a positive correlation between energy, carbohydrate and fat intake on NF-κβ expression (p = 0.001, 0.000, 0.046). However, there was a negative relationship between protein intake and NF-κβ expression (p = 0.000). This study concluded the modified AIN-93M HFHF diet increased NF-κβ expression in the liver tissue of male Sprague Dawley rats.
Protein-based virtual screening: SIRT-1 as modulator maturation of circulating endothelial progenitor cells
Authors: Wihastuti T A , Nurwidyaningtyas W , Tjahjono C T , Heriansyah T 
Published: November 2019

Abstract
Circulating endothelial progenitor cells (cEPCs) are having involvement in the replacing vascular endothelial cells damaged or detachment from the basement membrane. cEPC needs to fulfill both quantity and quality requirements in order to play this important role. After efflux from bone marrow to circulation, niche EPC necessary of maturation to reach the potential for re-endothelialization. Risk factors exposure for cardiovascular disease not only affect the quantity and quality of cEPC, but it is also to be involved in downregulation of SIRT1. SIRT1 downregulation is mostly associated with the mechanism of senescence. Objective. to predict the direction of SIRT-1 interaction with cEPC maturation that is validated with cEPC marker surface using the STRING DB method of protein interaction. Result. SIRT1 interacts with two proteins, inhibiting VEGFA and activating and inhibiting P53. P53 inhibits the expression of p16ink4a, a protein involved in cellular senessence and P53 through AKT involved in CD 309 and ITGA2B expression. Whereas there was a direct interaction of the expression of CD 309 through the VEGFA line; CD117; TIE-2; CD 144; CD62a. Conclusion. SIRT-1 is an intracellular protein that is involved in cellular anti-aging processes but is not directly involved in the expression of EPC marker surfaces.
Decision support system with TOPSIS method for lecturer appraisal in Universitas PGRI Madiun
Authors: Saifulloh S , Pamungkas R , Lenawati M 
Published: November 2019

Abstract
Assessment of lecturer at university is a form of activity to evaluate the performance of each lecturer. PGRI University of Madiun (UNIPMA) always strives to improve accreditation by improving quality with other universities. Making a decision support system is one way to assist in determining lecturer’s assessment in UNIPMA. This decision support system uses the TOPSIS method and will be developed using the Waterfall model. In this study to solve the problem of educator performance assessment that is UNIPMA lecturer. The assessment process includes qualifications of education, learning, research, and the number of community service activities that have been done. By using the TOPSIS method of counting process and giving the result of lecturer appraisal that has been roughed more efficient and precise. Based on the results of the research using lecturer data sampling of 10 educators obtained the highest value data is 0.75 (Very Good) where the range of decision assessment 1 - 0.65 (Very Good), 0.64 - 0.4 (Good), 0.39 - 0.25 (Enough) and 0.24 - 0 (Bad).
Fractionation of bioactive materials temulawak rhizome (Curcuma xanthorrhiza) on fungal Candida albicans in search of phytopharmaca
Authors: Novianti D , Kartika T 
Published: November 2019

Abstract

Candida albicans fungus is a microbiota in the human body that is opportunistic. In general, infections caused by C. albicans are called candidiasis. Some studies have shown that C. albicans is resistant to antifungal agents, so an alternative antifungal medication is needed at affordable and safe prices. One alternative is to increase the use of medicinal herbs. The purpose of the research was to study the possibility of utilizing the Temulawak rhizome as a phytopharmaca material to treat candidiasis disease by C. albicans infection. The specific objective is to isolate the bioactive material and to determine the class of antifungal active fraction of Temulawak rhizome against C. albicans. Isolation of temulawak rhizome by way of extracted by stratified using soxhlet, then done fractionation using the method of vacuum chromatography, then bioautographic test using thin plate chromatography. Testing of bioactive fraction temulawak rhizome using thin plate chromatography obtained purple color indicating the class of terpenoids compounds and yellow color indicating the class of phenols compounds. The fraction of methanol extract from Temulawak rhizome makes it possible to be used as raw material of phytopharmaca because it has antifungal effectiveness against C. albicans.
Feasibility analysis of laying hen business of pullet period
Authors: Puriastuti D P , Leondro H , Sodiq A 
Published: November 2019

Abstract
This research is aimed to find out the feasibility of business on chicken farm owned by Mr. Sahlan in Ngebruk Village, Poncokusumo Subdistrict, Malang Regency. The material used is laying hens pullet period with a population of 6000. The method used in this research is survey method with quantitative approach. The variables observed were revenue, production cost, profit, BEP, and R / C ratio. The research result showed that the acceptance of Rp. 308.312.000, production cost Rp. 274.238.151, BEP will be obtained if the sale price of livestock Rp. 35,588 / Kg and livestock sold 6,891.4 kg, R / C ratio of 1.12. Based on the results of the research can be concluded that the farm of laying hen pullet period belong to Mr. Sahlan deserve to continue.
Artificial Insemination using liquid sperm Filial Ongole Bull after sexed with different methods
Authors: Kusumawati E D , Susilawati T , Isnaini N , Rahayu S , Yekti A P A , Kuswati K , Ridhowi A , Rahadi S 
Published: November 2019

Abstract
The purpose of this study was to determine the success of artificial insemination (AI) using liquid sperm Filial Ongole Bulls after sexed by the percoll density gradient centrifugation (PDGC) and egg white sedimentation (EWS) sexed methods. The study materials were 135 cattle were inseminated using non sexed semen, PDGC and EWS sexed methods. Non-return rate (NRR) and the conception rate (CR) are observed. The research design used for the success of AI using chi square. The result of pregnancy examination at the age of 3 months found 21 head of pregnant cows from 45 cattle in AI with without sexed (control), 14 head of pregnant cattle from 45 cattle in the AI with EWS method, 18 head of pregnant cattle from 45 cattle in AI with PDGC method. The result showed that CR value using liquid sperm result of EWS, PDGC and without sexed were very significant (P <0.01). CR value is still higher sperm without sexed (46.67%) followed by PDGC (40%) and EWS (31.11%). The value of conception rate is lower than sexed using PDGC method. The success of AI showed better PDGC sexed method than EWS sexed method based on AI liquid sperm results with CR analysis.
Liquid waste pollution model and characterization levels from small-scale gold mining activities
Authors: Solihin S , Amukti R , Guntoro D 
Published: November 2019

Abstract
Small scale mining system carried out by local residents in Bunikasih, Sukaluyu Village, Pangalengan District, Bandung Regency causes environmental pollution and long-term ecosystem damage. This is because the mining method does not follow the rules set by the government. To find out the amount of pollution that has occurred, this study was conducted. The research methodology used starts from taking field data samples, then analyzes the chemistry for clean water and waste chemicals. From this study it was found that the presence of heavy metal mercury (Hg) due to mining activities and processing of gold ore using amalgamation with values in the upper reaches of Ciwiwi River = 0.085 mg / kg, in the area of amalgamation gold ore processing = 0.11 mg / kg, and in the lower reaches of Ciwiwi River = 0.097 mg / kg.
Implementation of Naïve Bayes updateable with modified absolute discount smoothing on Pamekasan Regent SMS center data classification
Authors: Said B , Dewi N P 
Published: November 2019

Abstract
Classification is a grouping process based on a predetermined class. Previous research has classified Regent Pamekasan SMS Center using Naïve Bayes and Modified Absolute Discounting (MAD) Smoothing, but the average classification accuracy is still equal to 76.83%. to improve the accuracy of classification then in this study applied Naïve Bayes Updateable by using MAD Smoothing. The classes used remain 15 classes: Education, Health, Infrastructure, Crime, Administrative Services, Sports, Government, Agriculture, Small and Medium Enterprises, Order, Weak Economy, Religion, Art and Culture, Natural Disasters, and Others. Before doing the classification process first done pre-processing such as equating characters, deletion of punctuation, restore abbreviation, translation of the local language (Madura), deletion of numbers, deletion of words that are not important in SMS, and stemming to convert into a basic word. Results Some experiments obtained an average accuracy of 78.89%, with the accuracy of one test reached 87.65%. And Naïve Bayes Updateable can increase accuracy by 2.07% with the addition of 0.47-minute classification time.
The role of electronic learning media in creativity learning
Authors: Hikmawan T , Sutarni N , Hufad A 
Published: November 2019

Abstract
Information technology at this time is the latest dimension that cannot be separated from human life. The field of education is the thing that gets the influence of information technology. Currently, the teaching and learning process not only rely on physical books and whiteboards, but with the help of electronic-based learning media. Electronic learning media is the latest breakthrough from the influence of information technology progress. The new facilities help actors in the world of education to improve the quality and quality of education to be more advanced and developed in the digital era of today. Improving the quality of education through intermediaries of electronic learning media can trigger the pattern of creativity in the actors of the world of education.
Inheritance process of West Java local-arts values based on multimedia communications
Authors: Wartika E , Ridwan I , Apip A 
Published: November 2019

Abstract
West Java is one of the provinces in Indonesia with a very vast culture and art heritage. Now, the local arts and cultures have been diminishing with times. This problem was caused mainly by the declining appreciation and the lack of attention from present generations. However, the communication media and technology can play important roles to promote them. This paper aims at examining how multimedia communication models can optimize the process of inheritance and preserve art and culture. The model was developed in such a way, so that the inheritance processes of arts culture can be adaptive with modern society that is characterized by the use of computer networks and applications. The method used in this research is qualitative, and the final results is a collection of West Java local arts documentary videos that are mapped with their associated Geographic Information System, namely “Geographical Mapping of Sundanese Art”. The communication pattern is adjusted without damaging the content and essence of the cultural arts that are processed. This model will become an effective way to disseminate the local arts, so that the community can have easier access to the documentary video of local culture, especially in West Java region.
Implementation weighted product method to determine multiple intelligence child
Authors: Ahsan M , Indawati N 
Published: November 2019

Abstract
Multiple Intelligence can be known through words, numbers, music, pictures, physical activity or motor skills in a social-emotional way. Multiple Intelligence is basically the development of brain intelligence (IQ), emotional intelligence (EQ), and spiritual intelligence (SQ). Intelligence is the ability possessed by a person to see a problem, then solve the problem or make something that can be useful for others. Intelligence or intelligence can be viewed as the ability to understand the world, think rationally, and use resources effectively when faced with a challenge. Some argue that the notion of intelligence is the general human ability to perform actions that have goals and think in a rational way. In addition, intelligence can also be interpreted as a personal ability to understand, innovate, and provide solutions to various situations. Multi Attribute Decision Making (MADM) is used in making decision support systems using Weighted Product (WP) to define child Multiple Intelligence. 8 intelligences with 8 criteria with specified weights. The data tested based on the data of new students who have enrolled in SMP Negeri 3 Kepanjen with the amount of data 226 students who have registered and fill in the questionnaire (indicator) that has been provided through www.teskecerdasan.com. The results of these are graphs that have been ranked based on the Weighted Product (WP) method villages.
Bi-conditional Cordial Labeling for Extended Duplicate Graph of Certain Classes of Graphs
Authors: Nandagopal E. , Maheswari V. 
Published: November 2019

Abstract
In this article we admit Bi- Conditional for Duplicate graph of Quadrilateral Snake EDG(QSm
)m ≥ 2, Double Quadrilateral SnakeGraphs EDG(DQSm
)m ≥ 2, and Triangular ladder graph. EDG(TQLm
)m ≥ 2.
Existence and uniqueness of solutions for boundary value problem of fractional order difference equations
Authors: George Maria Selvam A. , Abraham Vianny D. 
Published: November 2019

Abstract
In this article, we investigate the existence and uniqueness of solutions for boundary value problem (BVP) of fractional order difference equations (FODE) of the form

Δ
υ

w
(
s
)
=
−
f
(
s
+
υ
−
1
,
w
(
s
+
υ
−
1
)
)

,

w
(
υ
−
2
)
=
ψ
(
w
)
,
w
(
υ
+
k
)
=
ϕ
(
w
)

,
where s ∈ [0, k]
N
0
, f : [υ − 2, υ − 1, …, υ + k]
N

υ−2
× R [0, + ∞] is a continuous function ψ, φ : C ([υ − 2, υ + k]
N

υ−2
) → R are given functions and

1
<
υ
⩽
2

. Existence and uniqueness of solutions are established by the Brouwer fixed point theorem and contraction mapping principle.
Bi-Magic Labelings of Some Connected and Disconnected Graphs
Authors: Subbulakshmi Dr.S. , Kokila R. 
Published: November 2019

Abstract
Various graph labeling that generalize the idea of a magic square have been discussed. In particular, a magic labeling on a graph with v vertices and e edges will be defined as a one to one map taking the vertices and edges onto integers 1, 2,…, v+e with the property that the sum of the label on an edge and the labels of its end points is constant, independent of the choice of edge.