bluuebunny/crossref_metadata_2025_split huggingface dataset:
Debt to Equity Ratio, Fixed Asset Turnover and Profit Growth in Companies Listed on The BEI
Authors: Mursalini Wahyu Indah , Sriyanti Esi , Sari Irma Permata 
Published: February 2025

The aim of this research is to investigate how the debt to equity ratio and fixed asset turnover impact the growth of profits. The focus of this research will be on analyzing the financial records of companies within the food and beverage industry that are traded on the Indonesia Stock Exchange from 2019 to 2022. A total of 48 companies will be included in the study. Purposive sampling was utilized to select 31 companies for the study. Quantitative data was employed for analysis. The findings indicate that the debt to equity ratio has a partial but significant impact on profit growth. This is evidenced by the research results that the t-count value> t table (-2.186> 1.987) and a significance value of 0.032 <0.05. Thus, H1 in this study is accepted. According to the test results, it was found that profit growth is not significantly impacted by fixed asset turnover. This is evidenced by the research results showing the t-count value <t-table (-0.742 <1.987) and a significance value of 0.460> 0.05. Thus, H2 is rejected in this research. The results of the study suggest that both the debt to equity ratio and fixed asset turnover do not collectively influence profit growth to a noticeable extent. The research findings clearly demonstrate a calculated f value <f table (2.402 <3.10) and a significance value of 0.097> 0.05. Thus, H3 in this study is rejected. The value of 0.053 or 5.3% demonstrates this, with the remaining 94.7% being affected by unexplored variables.
A retrospective study of the correlation between high serum ferritin levels and the risk of gestational diabetes mellitus in midpregnant women
Authors: Fan Xizhenzi , Zhang Pan , Wang Lingli , Song Wenhui , Su Achou , Yu Tianxiao 
Published: February 2025

Aims
Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first detection during pregnancy, with an inconsistent association with serum ferritin (SF). We aimed to ascertain the relationship between SF and the risk of GDM in mid-pregnancy and provide evidence for implementing clinical individualized and reasonable iron supplementation regimens.

Methods
A retrospective study was conducted to investigate 1,052 pregnant women at 24–28 weeks of gestation who were examined in the obstetrics department of The Fourth Hospital of Shijiazhuang from January 2019 to December 2021. Questionnaires were used to obtain the general information. The levels of serum ferritin (SF), serum calcium, glycated haemoglobin (HbA1c) and Oral-Glucose-Tolerance-Test (OGTT) were reviewed. The GDM was diagnosed by glucose tests. Multivariate logistic regression was used to determine the relationship between serum ferritin and GDM.

Results
Compared to the non-GDM group, the GDM group had significantly higher level of SF (13.95 (8.59–23.65) ng/mL vs. 12.11 (7.27–19.86) ng/mL, (p = 0.012)). While SF levels positively correlated with 1-hour plasma glucose levels (PG1H) (r = 0.061, p = 0.047), there was a negative correlation between SF and HbA1c levels (r = − 0.078, p = 0.011). The risk of GDM with higher levels of SF was increased (1.010 (95% CI [1.001–1.020], p = 0.025)). In the univariate logistic regression model, the risk of GDM in pregnant women with high ferritin levels was 1.010 (95% CI [1.001–1.020], p = 0.025). After adjustment for age and pre-pregnancy body mass index (BMI), the risk of GDM was significantly increased by 44% and 42% respectively (adjusted odds ratio (AOR) = 1.440, 95% CI [1.025–2.023], p = 0.035), AOR = 1.420 (95% CI [1.011–1.995], p = 0.043). After multivariate adjustment for age and pre-pregnancy BMI, the results were moderately revised (AOR = 1.427, 95%CI [1.013–2.008], p = 0.042).

Conclusions
Elevated SF levels of mid-pregnancy was associated with risk of GDM, which may guide the implementation of pregnancy-specific supplementation to some extent with the support of further clinical trials.
Cytokine network in the central nervous system and its roles in growth and differentiation of glial and neuronal cells
Authors: Sawada Makoto , Suzumura Akio , Marunouchi Tohru 
Published: July 2002

AbstractCells resident within the central nervous system (CNS) can synthesize, secrete and respond to inflammatory cytokines not only contributing to the responses to injury or immunological challenge within the CNS, but also regulating their own growth and differentiation potential. The actions and cell communication via cytokines in the CNS are designated as the CNS cytokine network, in which microglia and astrocytes play the central roles. To further characterize the CNS cytokine network we investigated the differences in roles of these cells, and found that microglia might contribute to the early phase of cytokine production reaction and that astrocytes might contribute the late phase of the reaction. We also investigated roles of inhibitory cytokines such as TGF β, IL‐4, and IL‐10, and showed that each might play a distinct role in the inhibitory regulation in the CNS. We summarized our previous report about cellular distribution of cytokine receptors in the CNS cells and discussed their roles in the CNS cytokine network. Finally, we investigated that expression of IL‐6 and IL‐2 receptors in neuronal and oligodendrocytic differentiation, respectively. From these results, we discussed the features of the CNS cytokine network.
Outcome of 1040 consecutive breech deliveries: clinical experience of a maternity hospital in Turkey
Authors: Erkaya S , Tuncer R.A , Kutlar Ï , Onat N , Erçakmak S 
Published: July 2002

AbstractObjective: To determine the optimal route of delivery in breech presentation. Method: One‐thousand and forty singleton breech deliveries among a total of 41 785 deliveries that occurred at Zübeyde Hanim Maternity Hospital between 1990 and 1994 were analyzed. Result: The breech deliveries accounted for 2.4% of all deliveries. Of the patients, 572 (56.3%) were delivered vaginally and 468 (43.7%) were delivered by cesarean section. The mean ages of vaginal and cesarean delivery groups were 25.2 and 24.6 years, respectively. Forty‐one (3.9%) of the fetuses had congenital anomaly. The leading congenital anomalies were meningocele in seven and hydrocephalus in six patients. Mullerian anomalies were encountered in 29 (6.1%) patients at cesarean section. Fetal morbidity observed in cesarean deliveries were fracture of the humerus in one and fracture of the femur in one and soft tissue injury in four cases. Fracture of the humerus was observed in two, Erb's paralysis in four, facial paralysis in one and soft tissue injury in 43 fetuses delivered vaginally. The leading causes of puerperal maternal morbidity were genital tract lacerations in vaginal delivery group and wound infection in cesarean delivery group. The overall perinatal mortality of this series was 54.8/1000 (57/1040). The corrected figures for cesarean delivery and vaginal delivery groups were 8.5/1000 (4/467) and 57.9/1000 (32/552), respectively. Conclusion: We favor a selective approach for mode of delivery in patients with breech presentation in order to balance the fetal morbidity associated with vaginal delivery and maternal morbidity and cost associated with cesarean delivery.
Upper genital‐tract screening with hysterosonography in patients receiving donated oocytes
Authors: Lindheim S.R. , Sauer M.V. 
Published: July 2002

AbstractObjective: To compare the results of sonohysterography (SHG) for imaging of the uterine cavity to hysterosalpingogram (HSG) and hysterscopy (HSC) in order to assess its clinical utility for recipients of donated oocyte. Method: From January 1996 to December 1996, we evaluated all patients (n = 50) referred for ovum donation using SHG and compared the results with HSG obtained within 6 months of SHG. Patients having either an abnormal SHG of HSG underwent HSC for confirmation and treatment. SHG was routinely performed during the early follicular phase using 10 cc saline instilled through an intracervical H‐S catheter with concurrent vaginal sonography. Result: Pathology was observed and confirmed in 19 cases (38%) including polyps (n = 10, 52.6%), submucosal myomas (n = 7, 36.8%), intrauterine adhesions (n = 1, 5.3%) and bicornuate uterus (n = 1, 5.3%). SHG and HSG were concordant in 46 cases (95.8%) of which in 29 (60.4%) a normal cavity was observed, while four studies (8%) did not agree. Two polyps were missed on HSG, while two SHGs incorrectly diagnosed a calcified myoma and an endometrial fold. Using HSC for definitive identification, the accuracy of SHG was 90%, and similar to HSG. Conclusion: SHG appears both sensitive and highly predictive for evaluating pathology of the endometrial cavity and appears to be as effective as HSG. Advantages of SHG include improved imaging or uterine pathology, cost, greater patient comfort and the avoidance of radiation. Routine SHG of recipients uncovered a high incidence of abnormalities in older women and underscores the need to evaluate the uterine cavity prior to ovum donation.
Implementing family planning programs in developing countries: lessons and reflections from four decades of Population Council Experience
Authors: Catley‐Carlson Margaret 
Published: July 2002

AbstractOver the last three decades, contraceptive prevalence has risen from about 10% to nearly 60% in developing countries, but still about 1 in 4 births in developing countries (outside China) is unwanted. More than 120 million women in these countries who do not want to become pregnant do not use contraceptives. Nearly 600 000 women die each year from pregnancy‐related causes, between 67 000 and 204 000 of them from unsafe abortions. At the 1994 International Conference on Population and Development in Cairo, delegates endorsed the view long advocated by the Population Council: the primary purpose of family planning programs should be to help women avoid unwanted pregnancy and achieve their fertility goals safely. That means, at the very least, that programs should address those reproductive health issues that are directly related to fertility regulation. To meet the Cairo challenge, progress is needed simultaneously on several levels. We need more and better contraceptive technologies that meet the needs of different groups; higher‐quality family planning services; more outreach to underserved groups (such as men and adolescents); programs tailored to local cultures; and measures to address all the factors that prevent women who do not want to become pregnant from using contraceptives. The call for a client‐centered, reproductive health approach to family planning constitutes a critique of programs driven by demographic goals. The new family planning paradigm puts a premium on ‘quality of care’. Unfortunately, many family planning programs still fall substantially short of offering clients reproductive choice and supporting their reproductive health. The Population Council takes the view that contraceptive research and development is an essential component of a multilevel strategy to reduce unwanted fertility safely. New products, used ethically and provided with quality, would be of tremendous benefit to women and men throughout the world. The Population Council has developed, registered, and licensed seven products, including some of the most widely used contraceptives in the world. The Council is also one of the world centers for research on male reproductive physiology and male contraception. New contraceptive methods are only as good as the context in which they are offered. To accelerate the pace of overall fertility decline, governments must adopt policies that reduce the economic and social risks associated with having smaller families, and policies that promote later and planned childbearing.
HIV and women in Thailand: severity and services
Authors: Koetsawang S. , Auamkul N. 
Published: July 2002

AbstractThailand has extensive data on the emergence of HIV and aggressive prevention programs to prevent the spread of the disease. The increasing HIV infection among women who desire pregnancy increases the number of HIV‐infected infants. Standard guidelines for HIV testing include that the test should be voluntary, counseling should be given before and after testing, the test results should be kept strictly confidential, AIDS education should be provided for all hospital personnel, and an appropriate hospital policy on AIDS is in place. In HIV positive women decisions about pregnancy termination or continuation is usually made by both husband and wife after counseling about the possibility of perinatal transmission. The current practices in Thailand of patient care, antenatal care, management of labor, breast feeding and contraceptive practice are reviewed.
Invasive carcinoma of the uterine cervix in Iran
Authors: Haghdel M , Ardakany M.S , Zeighami B 
Published: July 2002

AbstractObjective: To review diagnostic aspects, treatment measures and pathologic findings in patients diagnosed and treated for invasive cervical carcinoma in Shiraz University of Medical Sciences hospitals. Method: The hospital records of all patients admitted to the Shiraz University of Medical Sciences affiliated hospitals (Nemazee and Saadi hospitals) with newly diagnosed carcinoma of the uterine cervix between January 1985 and December 1995, were reviewed. Results: 204 newly diagnosed patients were admitted with invasive cervical carcinoma of which 61 (30%) were in stage I (FIGO), 96 (47%) in stage II, 34 (16.6%) in stage III and 13 (6%) in stage IV of the disease. Of these 204, the given treatments included surgery in 88 patients, internal and external pelvic radiotherapy in 141, both hysterectomy and pelvic radiotherapy in 22, chemotherapy in eight and cryotherapy in one patient. We found significantly positive relations with stage of the disease and chest roentgenogram (P<0.02), intravenous pyelogram (P<0.0002), sigmoidoscopy (P<0.006) and cystoscopy (P<0.0045). Of the total number of pathologic specimens, squamous cell carcinoma was reported in 88% and adenocarcinoma in 11%. Recurrence rates of up to 15.5% for stage II and 5% for stage I were calculated. Among the complications for which hospital admission was required, genito‐urinary complications were the most frequent. Conclusion: The recurrence rate in stage I is lower than the estimated recurrence risk in several other studies which can be due to a real advantage of the center's practice. This may pose the question of indispensability for the advanced and expensive diagnostic paraclinical work‐ups.
Firm characteristics, total quality management, and financial performance
Authors: Hendricks Kevin B , Singhal Vinod R 
Published: July 2002

AbstractThis paper uses a sample of quality award winners to empirically test hypotheses that relate changes in operating income associated with effective implementation of total quality management (TQM) to various firm characteristics. The characteristics examined are firm size, the degree of capital intensity, the degree of diversification, the timing of TQM implementation, and the maturity of the program. We find that smaller firms do significantly better than larger firms. Firms that have won awards from independent award (a proxy for more mature TQM implementation) do significantly better than just supplier award winners. The evidence weakly supports the hypotheses that less capital‐intensive firms do better than more capital‐intensive firms, and more focused firms do better than more diversified firms. Finally, we do not observe any significant differences between the performance of earlier and later implementers of effective TQM.The key implications of these results are that many organizational characteristics moderate the benefits of TQM implementation. Although not all of these characteristics are controllable by managers, managers must set realistic expectations for the degree of benefits from TQM. The results for size and capital‐intensity validate the importance of TQM practices for smaller firms and environments that are more labor intensive. Investing to achieve a broader, deeper, and more mature TQM implementation (possibly by targeting an independent TQM award) should also result in higher benefits from TQM implementation. Furthermore, the results indicate that it is never too late to invest in TQM.
Hopes for the future of operations management
Authors: Meredith Jack R. 
Published: July 2002

AbstractOperations Management has a much longer history than our sister functions in business: finance, marketing, accounting, etc. Yet, we still struggle with fewer majoring students, fewer and newer journals, less academic respect, greater student fear, and fewer professors. Yet, most of the physical and human assets in real‐world organizations are still in the operations function and most of the excitement in industry lies in the operations area: TQM, JIT, supply chain management, ERP, mass customization, and so on. This paper will address some hopes for our future regarding practice, teaching, and research.
Process‐technology fit and its implications for manufacturing performance
Authors: Das Ajay , Narasimhan Ram 
Published: July 2002

AbstractThis study investigates the issue of fit between process environment and advanced manufacturing technology, and its impact on manufacturing and business performance. We find that different process environments tend to align advanced manufacturing technology investments in distinct profiles, which are associated with superior performance. Deviations from these ‘ideal’ profiles are shown to have a negative impact on manufacturing performance. The findings also suggest that firms are not fully exploiting the potential afforded by AMT investments to compete in off‐diagonal positions in the Hayes–Wheelwright framework.
Processes with nearly‐sequential routings: a comparative analysis
Authors: Monahan George E , Smunt Timothy L 
Published: July 2002

AbstractRecent advances in automated technology have made it possible to incorporate many of the benefits of flow lines in the production of low‐to‐medium volume products found in a batch environment. The use of automated technology and cellular manufacturing tends to induce flows that are nearly sequential—the level of flow dominance is high, but it is not as high as the level associated with a pure flow shop. While a number of prior research studies have examined the performance of specific process configurations, such as those associated with cellular manufacturing, group technology and flexible manufacturing systems, ours is the first to analyze the effects of flow dominance in a more general setting. In this paper, we study the effect on process performance of slight departures from purely‐sequential flows. To obtain generalizable results, we use a full factorial simulation experiment to examine both the main and interaction effects of product attributes, such as the number of products and job size, and of process attributes, such as operation‐time variance, setup time, parallel processing capability and flow dominance. Our results provide insights into the performance of a wide variety of batch production processes, including, as special cases, cellular manufacturing, jobs shops, and flow shops. We show that the performance of such systems, as measured by average flow times and flow time variance, can be substantially improved by eliminating even a small number of remaining non‐standard routings, particularly when setup times are moderate‐to‐high or operation‐time variation is low‐to‐moderate.
Order review/release in the absence of adherence to formal scheduling policies
Authors: Philipoom Patrick R , Fry Timothy D 
Published: July 2002

AbstractIn many plants, the performance of shop floor workers is measured by accounting‐based productivity criteria. Such systems encourage workers to maximize their individual performance, often at the expense of total shop performance. One such company, Union Switch & Signal, a manufacturer of railroad equipment, has decided to increase finished goods inventory in an effort to counteract poor due date performance. Management at Union Switch & Signal feel that workers not following priorities contribute significantly to this poor performance. It has been suggested that the controlled release of jobs into the shop, i.e., Order Review/Release (ORR), may provide the operations manager a vehicle for enforcing job priorities when formal dispatching rules are not strictly followed by workers. In this study, two ORR methodologies are studied in regards to their ability to offset the dysfunctional behavior by workers who seek to maximize their own individual productivity. This type of behavior was captured by simulating the phenomenon of ‘cherry picking’. Cherry picking occurs when a job is selected for processing based not on its formal priority but on the difference in standard allowable processing time and actual processing time. Results suggest that at least one ORR methodology is able to reduce the difference in resulting labor productivity while improving overall shop performance.
2′3′cyclic nucleotide 3′phosphodiesterase immunohistochemistry shows an impairment on myelin compaction in hypothyroid rats
Authors: Barradas Penha C. , Ferraz Alessandra S. , Ferreira Andréa A. , Daumas Regina P. , Moura Egberto G. 
Published: July 2002

AbstractThe effects of hypothyroidism on oligodendroglial differentiation and myelination are for the first time studied by immunohistochemical localization of an early oligodendroglial marker, the 2′3′cyclic nucleotide 3′phosphodiesterase (E.C. 3.1.4.37‐CNPase), in developing rats. Two groups received methimazol; one during gestation (H) and another postnatally (PN). One H sub‐group received thyroxine after birth (T). We observed a delay in CNPase expression followed by a decrease in the number of CNPase immunoreactive fibers in both H and PN groups. The T sub‐group was not different from controls. Furthermore, the immunoreactive fibers, in mature hypothyroid animals, showed a continuous pattern of staining in contrast with a discontinuous one in controls.Myelinogenesis is a highly regulated timed event. CNPase links myelin related proteins to the cytoskeleton also interacting with membrane lipids during extension and wrapping of the oligodendroglial process around the axon (ensheathment phase). In mature myelinated fiber the CNPase is absent from compact myelin sheath, being located only in the inner and outer loops and in paranodal loops. Thus, our data suggest a disorder in myelin compaction and point once more to the post‐natal period as critical for the mechanisms that are thyroid hormone regulated in myelinogenesis.