bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complejidad textual con fines académicos en el ámbito de la traducción. Variables para su clasificación.
Authors: Muñoz López Fernando Javier 
Published: January 2020

La actividad traductora es de por sí un proceso complejo en cuanto al conocimiento. Para lograr llevar el mensaje de una lengua a otra, existen convenciones lingüísticas y culturales que deben ser consideradas. La complejidad en el ámbito terminológico (Cabré, 2003), es una variable que puede incidir directamente en el aprendizaje tanto del proceso traductor como del aprendizaje de una lengua, si no existen criterios pedagógicos claros sobre la selección de material académico para el educando. El objetivo de esta investigación fue crear un insumo para la categorización y clasificación de niveles de complejidad de textos considerando los criterios baja, media y alta complejidad, y así intentar estandarizar el proceso de selección de material para aplicar metodologías a programas universitarios de la carrera de traducción. Con lo anterior, se busca definir criterios elementales, en formato de material instruccional, para que en cada programa de estudio donde se vea reflejada la competencia del saber-hacer ligada a la traducción, la selección de textos de la lengua meta no sea sesgada al juicio experto sino a características fundamentales de selección académica para poder cumplir con las competencias y aprendizajes esperados de los programas de estudio de la carrera de traducción en INACAP Chile y su respectivo perfil de egreso. Translation activity is by nature a complex process in terms of knowledge. There are linguistic rules and cultural guidelines in order to communicate one’s message to another language. Terminology complexity (Cabré, 2003) is an important variable that can directly affect translation learning and second language acquisition, when not considering teaching criteria in selecting academic texts for the students. The final objective of this project was to create an instrument that allows teachers to select and classify the complexity levels stated in each translation class program for low, intermediate and high complexity texts. This is to standardize the text selection process to which the students are exposed to when learning translation at INACAP University. The project aims to define the fundamental criteria in an instructional portfolio, so as each program can develop a competence-based approach related to the translation, the selection of source texts to translate is not up to each teacher’s expert opinion, but to the fundamental features of the academic text selection. All this is in order to accomplish the objective of each class program and achieve the exit profile.
The Barley Stripe Mosaic Virus expression system reveals the wheat C2H2 zinc finger protein TaZFP1B as a key regulator of drought tolerance
Authors: Cheuk Arnaud , Ouellet François , Houde Mario 
Published: January 2020

Abstract
Background Drought stress is one of the major factors limiting wheat production globally. Improving drought tolerance is important for agriculture sustainability. Although various morphological, physiological and biochemical responses associated with drought tolerance have been documented, the molecular mechanisms and regulatory genes that are needed to improve drought tolerance in crops require further investigation. We have used a novel 4-component version (for overexpression) and a 3-component version (for underexpression) of a barley stripe mosaic virus-based (BSMV) system for functional characterization of the C2H2-type zinc finger protein TaZFP1B in wheat. These expression systems avoid the need to produce transgenic plant lines and greatly speeds up functional gene characterization. Results We show that overexpression of TaZFP1B stimulates plant growth and up-regulates different oxidative stress-responsive genes under well-watered conditions. Plants that overexpress TaZFP1B are more drought tolerant at critical periods of the plant’s life cycle. Furthermore, RNA-Seq analysis revealed that plants overexpressing TaZFP1B reprogram their transcriptome, resulting in physiological and physical modifications that help wheat to grow and survive under drought stress. In contrast, plants transformed to underexpress TaZFP1B are significantly less tolerant to drought and growth is negatively affected. Conclusions This study clearly shows that the two versions of the BSMV system can be used for fast and efficient functional characterization of genes in crops. The extent of transcriptome reprogramming in plants that overexpress TaZFP1B indicates that the encoded transcription factor is a key regulator of drought tolerance in wheat.
Elastography for the Diagnosis of High-Suspicion Thyroid Nodules Based on the 2015 American Thyroid Association Guidelines: A Multicenter Study
Authors: Li Hairu , Peng Yulan , Wang Yan , Ai Hong , Zhou Xiaodong , Yang Lichun , Yan Kun , Xiao Ying , Liu Lisha , Luo Baoming , Yong Qiang , Cong Shuzhen , Jiang Shuangquan , Fu Xin , Ma Buyun , Li Yi , Zhang Xixi , Gong Xue , Chen Haitao , Liu Wenying , Tang Ling , LV Xiaoyu , Zhao Xinbao , Li Liang , Gan Kehong , Tian Jiawei 
Published: January 2020

Abstract

Background:An accurate diagnosis for high-suspicion nodules based on the 2015 American Thyroid Association (ATA) guidelines would reduce unnecessary invasive examinations. Elastography is a useful tool for discriminating benign and malignant thyroid nodules.Aims:To investigate the diagnostic efficiency of elastography for high-suspicion thyroid nodules based on the 2015 ATA guidelines in the Chinese population.Materials and Methods:Thyroid nodules with high-suspicion characteristics based on the 2015 ATA guidelines were subjected to conventional ultrasound (US) and ultrasound strain elastography (USE) examinations at 12 hospitals from 4 geographic regions across China. Cytology/histology of thyroid nodules was used as a reference method. Receiver operating characteristic (ROC) curves were plotted to evaluate the diagnostic performance of the elasticity score (ES) and strain ratio (SR). Logistic regression analysis was used to determine the predictors of malignancy.Results:Overall, a total of 1445 thyroid nodules (834 malignant, 611 benign) from 12 centers were included in the final analysis. The areas under the curve of the ES and SR were 0.828 and 0.732, respectively. The sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of the ES were 92.4%, 60.7%, 79.0%, 76.3% and 85.5%, respectively, and those of the SR were 81.1%, 50.1%, 68.9%, 65.9% and 67.9%, respectively. The combination of the Thyroid Imaging Reporting and Data System (TI-RADS) and ES led to a significant increase in the sensitivity and NPV (97.1% and 91.9%, respectively) compared with the TI-RADS alone. Logistic regression analysis showed that microcalcifications (OR=5.290), taller than wide (OR=12.710), irregular margins (OR=10.117), extrathyroidal extension (ETE; OR=6.412), the ES (OR=3.741) and the SR (OR=1.083) were independent predictors of malignant thyroid nodules. The sensitivity, specificity, accuracy, PPV and NPV of the ES were all superior in nodules ≥1 cm than in those <1 cm (95.0% vs 90.4%, 68.8% vs 56.8%, 85.9% vs 74.4%, 85.2% vs 69.9%, and 87.8% vs 84.2%, respectively).Conclusions:Elastography combined with the ES is a valuable tool for the assessment of high-suspicion thyroid nodules based on the 2015 ATA guidelines, especially in nodules ≥1 cm.
Sexual orientation disparities in food insecurity and food assistance resource use in U.S. adult women: National Health and Nutrition Examination Survey, 2005-2014
Authors: Patterson Joanne G , Russomanno Jennifer , Tree Jennifer M Jabson 
Published: January 2020

Abstract

Background. Nearly 40 million American adults report past year food insecurity. This is concerning, as food insecurity is associated with chronic disease morbidity and premature mortality. Women disproportionately experience food insecurity, and sexual minority women (i.e., lesbian, bisexual, and heterosexual women reporting same-sex behavior) may be at greater risk for experiencing food insecurity disparities. The purpose of this study was to investigate patterns and prevalence of food insecurity and food assistance resource use in sexual minority and exclusively heterosexual women using population-level health surveillance data.

Methods. We pooled 2004-2014 National Health and Nutrition Examination Survey data. Women were classified by sexual identity and lifetime same-sex behavior to create subgroups of lesbian, bisexual, heterosexual women reporting same-sex behavior (heterosexual WSW), and exclusively heterosexual women. We compared groups on past 12-month food insecurity, severe food insecurity, Supplemental Nutrition Assistance Program (SNAP) and emergency food assistance resource use using multivariable Poisson regression models to estimate weighted prevalence ratios.

Results. Lesbian, bisexual, and heterosexual WSW were more likely to report past 12-month food insecurity and severe food insecurity than exclusively heterosexual women: prevalence ratios (PR) ranged from 1.37 (95% confidence interval [CI] = 1.07,1.75) to 1.77 (95% CI = 1.08-2.91). No differences were found in SNAP participation by sexual orientation, but more lesbians and heterosexual WSW reported using emergency food assistance in the past 12-months (PR = 1.96; 95% CI = 1.34, 2.88 and PR = 1.47; 95% CI = 1.05, 2.06 respectively).

Conclusions. Food insecurity—including disrupted eating patterns and reduced food intake—is overrepresented in sexual minority women. Lesbians and heterosexual WSW are also more likely to rely on emergency food assistance. This is problematic as SNAP use may reduce food insecurity over time, but emergency food resources (e.g., food pantries) do not. More evidence is needed to understand the multilevel factors driving food insecurity in this population, with to develop policy and community-based efforts to increase SNAP participation and decrease food insecurity.
Comparison of Clinical Results of Anteromedial and Transtibial Femoral Tunnel Drilling in ACL Reconstruction
Authors: Metso Leena , Nyrhinen Kirsi-Maaria , Bister Ville , Sandelin Jerker , Harilainen Arsi 
Published: January 2020

Abstract
Background: This study compares long term results of two femoral bone tunnels in anterior cruciate ligament (ACL) reconstruction. The femoral tunnel can be drilled transtibially (TT) or through an anteromedial portal (AM). Methods: 300 patients with ACL reconstructions were chosen for this study. They were divided into two groups: 150 patients with anteromedial drilling (AM) and 150 with transtibial (TT) drilling. In the AM group the reconstructions were performed using semitendinosus graft with Tape Locking Screw (TLS™) technique (n=87) or Retrobutton™ femoral and BioScrew™ tibial fixation with a semitendinosus-gracilis graft (n=63). In the TT group the fixation method used was Rigidfix™ femoral and Intrafix tibial fixation. The evaluation methods were clinical examination, knee scores (Lysholm, Tegner, IKDC) and instrumented laxity measurements (KT-2000™). Our aim was to evaluate if there is a better rotational stability and therefore better clinical results when using AM drilling. Results: In the AM group there were 18 and in the TT group 17 revision procedures which were excluded from the study, leaving 132 patients in the AM group and 133 in the TT group for evaluation. In the one year follow-up there were 90 patients (68,2 %) in the AM group and 86 patients (64,7 %) in the TT group. In the two year follow-up there were 60 (45,5 %) and 58 (43,6 %) patients, respectively. The Tegner activity level was consistently higher in the TT group from preoperatively to two year follow-up postoperatively (p < 0.05). The IKDC score was better at two year follow-up in the TT group (p < 0.05). Statistical analysis was done using the BMDP Statistical Package (Statistical Solutions Ltd, Cork, Ireland). Conclusion: There was a statistically significant difference in IKDC score at two year follow-up, in favor of the TT drilling group compared with the AM group (p < 0.05). No other differences were found between these groups. Both drilling techniques resulted in improved patient performance and patient satisfaction. Also, we found no data supporting the hypothesis that AM drilling technique provides better rotational stability to the knee. Trial registration: ISRCTN16407730 Keywords: Anterior cruciate ligament reconstruction; clinical outcome; anteromedial; transtibial
Prenatal diagnosis and pregnancy determination of sex chromosome aneuploidy screened by non-invasive prenatal testing from 52,453 unselected singleton pregnancies: a retrospective analysis of 4-year experience
Authors: Luo Xiaojin , Hu Liang , Pei Yuanyuan , Cong Xiaoyi , Liu Xiaoyi , Chen Jing , Li Gaochi , Wen Lijuan , Liu Jinxing , Ran Jian , Wei Fengxiang 
Published: January 2020

Abstract
Objective To estimate the positive predictive value (PPV) of fetal sex chromosome aneuploidy (SCA) screened in non-selective population and explore the rate of pregnancy termination and ultrasound findings for fetal SCA and the factors influencing parents’ decisions in South China.Methods This is a large-scale retrospective cohort of positive SCA screened from unselected singleton pregnancies by non-invasive prenatal testing (NIPT) from a single prenatal center of a tertiary hospital, from January 2016 to November 2019. Clinical information, indications, diagnostic results, ultrasound findings, pregnancy determinations, and follow-up were reviewed and analyzed.Results 248 cases of SCA positive were screened out of 52453, giving a positive detection rate of 0.47%. The majority of indications (42.7%) were low-risk pregnancies. After genetic counseling, 43 pregnancies (17.3%) declined to prenatal diagnosis, the rest of 205 cases (82.7%) conducted with amniocentesis to detect fetal chromosome, of which 95 were confirmed as true positive of SCA with PPV of 46.3% (95/205). The SCA consisted of 68 sex chromosomal trisomies (26 cases of 47,XXY, 20 cases of 47,XXX and 22 cases of 47,XYY), 17 cases of monosomy X (45,X), three cases of 48,XXYY, three cases of mosaicisms (45,X/46,XX), four cases with sex chromosomal deletions, included two cases of 46,X,del(Y)(q11.21), one case of 46,X,del(X)(p11) and one case of 46,X,i(X)(q10). Of the 95 cases confirmed as true positive SCA, 50 cases (52.6%)chose to terminate the pregnancy (82.6%, 64.3%, 17.6% and 33.3% for 45,X, 47,XXY, 47,XXX and 47,XYY, respectively), 45 cases (47.4%) elected to continue the pregnancy. Ninety-three pregnant were also continued pregnancy after the exclusion of SCA.Conclusions NIPT, as a first-tier routine method for screening autosomal aneuploidies, also could play an important role in screening SCA. Low-risk pregnant women are the main indication for the detection of SCA as NIPT test provides to non-selective population. The trend of overall termination rates of SCA-affected pregnancies is decreased. For 47,XXX and 47,XYY with mild phenotype, couples would like to continue the pregnancy. But for 45,X and 47,XXY, parents apt to terminate pregnancy no matter ultrasound abnormalities were found or not. pregnancy determinations are affected by types of SCA, sonographic findings, maternal age, and presence of infertility.
Growth and Elongation of Axons through Mechanical Tension Mediated by F luorescent-Magnetic Bifunctional Fe3O4 ·Rhodamine 6G @PDA Superparticles
Authors: Wang Yang , Li Binxi , Xu Hao , Du Shulin , Liu Ting , Ren Jingyan , Zhang Jiayi , Zhang Hao , Liu Yi , Lu Laijin 
Published: January 2020

Abstract
Background: The primary strategy to repair the peripheral nerve injuries is to bridge the lesions by promoting axon regeneration. Thus, the ability to direct and manipulate neuronal cells axon regeneration has been one of the top priorities in the field of neuroscience. A recent innovative approach for remotely guiding neuronal regeneration is to incorporate magnetic nanoparticles (MNPs) into cells and transfer the MNPs-loaded cells into magnetic sensitive environment to response to external magnetic field. In order to realize this intention, synthesis and preparation of an ideal MNPs appears to be a challenge to overcome. Results: In this study we design and prepare a type of novel Fluorescent-Magnetic bifunctional Fe3O4·Rhodamine 6G@polydopamine Superparticles (FMSPs) for neural regeneration therapeutics. With the help of their excellent biocompatibility and ability to interact with neural cells, our homemade FMSPs can be endocytosed into cells, transported along the axons, and then aggregated in the growth cones. As a result, the mechanical forces generated by FMSPs are capable to promote the growth and elongation of axons and stimulate gene expression associated with neuron growth under the external magnetic fields.Conclusions: Our work demonstrates that FMSPs can be used as a novel stimulator to promote the non-invasive neural regeneration through cell magnetic actuation.
The NR5A1 mutation was identification in male infertility
Authors: Lu Yu-bin , Zhang Hong-guo , Yu Yang , Li Lei-lei , Li Lin-lin , He Jing , Liu Rui-Zhi 
Published: January 2020

Abstract
Background: Recent surveys report one in seven couples with infertility worldwide of which male infertility accounts for 30-50%. Azoospermia is one of the most serious forms of male infertility in men, the reason is that no sperm in the semen and genetic basis remains largely unknown. However, the cause of the disease and the genetic mechanism are still unclear. The aim of this study was to investigate the association between Chinese infertile men and mutation of NR5A1 (Nuclear receptor subfamily 5 group A member 1) gene. Methods: In order to study the mutations related to spermatogenesis genes in male with azoospermia,we sequenced the entire coding region of 52 genes related to sepermatogenesis in 200 infertile Chinese men. Screening for genetic variation and SNPs throughout the coding region by targeted exome sequencing. One previously described missense p.G197E was detected in exon 5 while no mutations were found in other exons. We performed Sanger sequcencing and confimed heterozygous missense mutation in the patient. Results: This patient has a normal karyotype with 46,XY and no abnormality exist in Y chromosome and hormone levels are changed. (eg:FSH, LH, E2, T). FSH is higher than normal, LH is higher than normal, E is lower than normal, PRL is within the normal range, T is lower than normal. Combining the results of this experiment, NR5A1 gene mutation may be associated with male infertility but to confirm this hypothesis more in-depth research is required. Conclusion: In a word, our research reveals a mutation in c.G590A (p.G197E) in NR5A1 which extended the mutation of NR5A1 in Chinese infertile men and increased awareness of infertility caused by azoospermia.
Corneal Thickness and Endothelial Morphology in Normal Thai Eyes
Authors: Tananuvat Napaporn , Khumchoo Natawan 
Published: January 2020

Abstract
Background: This study aimed to determine the influence of age on central corneal thickness and corneal endothelial morphology as well as to identify the relationship between them in normal Thai eyes.Methods: Non-contact specular microscopy was performed in volunteers stratified into seven age groups ranging from 11-88 years. The corneal endothelial parameters studied included central corneal thickness (CCT), endothelial cell density (ECD), coefficient of variation in cell size (CV), cell area (CA) and percentage of regular hexagonal cells.Results: In a total of 501 subjects (1002 eyes), the mean age was 43.12 ± 18.80 years and 347(69.3%) were females. The mean CCT, ECD, CV, CA, and hexagonality was 533.80 ± 33.00 μm, 2,732±258 cell/mm2, 37.61 ± 6.76%, 369.04 ± 37.90 mm, and 49.03% ± 7.53%, respectively. There was a statistically significant inverse correlation between age and CCT (r = -0.212, P <0.001), ECD (r = -0.484, P <0.001), and hexagonality (r = -0.193, P <0.001). The estimate rate of endothelial cell loss was 0.2% per year, whereas CV and CA had statistically significant correlation with age (r = 0.200, P <0.001 and r = 0.475, P <0.001). CCT correlated directly with ECD (r = 0.177, P <0.001).Conclusion: Normative data for corneal endothelial morphology in healthy Thai eyes showed that ECD, CCT, and hexagonality were significantly decreased, while CV and CA were increased with aging. The central corneal thickness was correlated with the endothelial cell density.
Human Immune Virus positive status disclosure to a sexual partner and associated factors among adult clients in Debre Markos town, 2019
Authors: Shiferaw Mengistu Benayew , Teshome Muluken , Zeleke Haymanot , Ayalew Agumas Fentahun 
Published: January 2020

Abstract
Background Human Immune Virus’ positive status non-disclosure to a sexual partner is a public health problem where a high prevalence of Human Immune Virus infection is reported on a region with poor partner disclosure status. The aim of this study was to assess Human Immune Virus positive status disclosure to sexual partners and associated factors among adult Human Immune Virus positive clients at Debre Markos town, Amhara Regional State Ethiopia, in, 2019. Methods Facility based cross-sectional study was done among 421 adult Human Immune Virus positive clients in Debre Markos town from September 1-30-2019. Consecutive sampling was used to collect the data. Epidata version 3.1 for data entry and SPSS version 25 for data analysis were used. Hosmer-Lemeshow goodness test of model fitness was checked. Bivariable and multivariable logistic analysis (p<0.05) was performed. Results The median age of participants was 35 years with (IQ of 30-42). Human Immune Virus positive status disclosure was 73.4% (95%, CI: 69-78). Male Sex (AOR=3.04; 95%, CI: 1.75-5.27), urban residence (AOR=2.57; 95%, CI: 1.39-4.77), Good antiretroviral treatment adherence status (AOR=3.18; 95%, CI: 1.58-6.39), stayed 39 months and above on antiretroviral treatment (AOR=4.53; 95%, CI: 2.31-8.88), Knowing sexual partner`s Human Immune Virus status (AOR=2.74; 95%, CI: 1.63-4.63) and provider-initiated Human Immune Virus testing (AOR=2.18; 95%, CI: 1.21-3.92) were statistically significant associated factors with Human Immune Virus status positive status disclosure. Conclusions and recommendation Human Immune Virus’ positive status disclosure to sexual partner was low. Sex, Residence, Duration of Anti-Retroviral Treatment, Adherence status to antiretroviral treatment, provider-initiated Human Immune Virus testing and knowing sexual partner`s Human Immune Virus status have had a statistically significant association with disclosure. It is better to promote provider-initiated Human Immune Virus testing and give special attention to females and rural residents regarding Human Immune Virus status disclosure to sexual partners.