bluuebunny/crossref_metadata_2025_split huggingface dataset:
La musicoterapia como acompañamiento al duelo migratorio: un estudio de caso único sobre la identidad/
Authors: Howe Ana , Pérez-Eizaguirre Miren 
Published: July 2020

Objetivos: Facilitar la expresión emocional, contribuir a la reducción de la regresión psicológica, acompañar en el proceso de cambio de personalidad de un duelo migratorio.Método: El procedimiento se ha basado en la creación de música en vivo según el modelo Nordoff-Robbins o humanista-creativo de musicoterapia. Resultados: La creación de un espacio de confianza para la expresión y gestión emocional, eliminación de elementos jerarquizantes y empoderamiento que permite la mejora de la autoestima así como, la construcción de una nueva identidad y la dotación de herramientas para el afrontamiento de futuras dificultades. Conclusiones: Este estudio de caso único permite ver cómo el modelo de musicoterapia Nordoff-Robbins admite un trabajo de acompañamiento en la elaboración de un duelo migratorio, imprescindible para la gestión emocional y cognitiva de un desplazamiento geográfico que conlleva un cambio vital, motivado por una pérdida. Es posible gracias al papel que juega la improvisación y la creación musical en vivo, ya que sitúa como responsable al participante de la formación de su proceso, manejando su propia situación que, a su vez, facilitará la gestión en el futuro de cualquier nueva dificultad. Al mismo tiempo resulta una herramienta que deja a un lado las barreras de comunicación formadas por la distancia cultural, la lengua o experiencia dispar, al establecer una vía alternativa para ello, donde las diferencias quedan resueltas a través del oído.
Poliquistosis Ovárica
Authors: Cardona Fernando 
Published: July 2020

Se estudian 321 ovarios poliquísticos, y se clasifican en variedades de acuerdo a un esquema propuesto. Se presenta una prueba dinámica hormonal, aplicando progesterona y dosificando el pregnandiol por metodo cromatográfico en capa delgada de Silica Gel G. Se analiza la utilidad de esta prueba para valorar la actividad androgénica y la progestacional de la gónada, en pacientes a las cuales se les practicó posteriormente estudio histológico de su poliquistosis ovárica.
II. · Ruptura prematura de membranas. Aspectos bacteriológicos
Authors: Rocha Posada Hernando , Velasco Chiriboga Alvaro , Valderrama Elsa 
Published: July 2020

Un total de 109 pacientes con ruptura prematura de membranas fueron estudiadas bacteriológicamente. Los especímenes estuvieron constituidos por líquido amniótico tomado por vía vaginal y/o abdominal, placenta, sangre del cordón umbilical y material naso-faríngeo y rectal en el niño. Cuando éste nació muerto, se cultivaron sangre auricular, contenido intestinal y trozos de bazo y pulmón. Se investigaron bacterias aerobias, anaerobias y hongos. Un total de 100 pacientes presentó cultivos positivos.
Las bacterias más comúnmente halladas fueron: E. coli, E. intermedium, Paracoli, P. aeruginosa, E. freundii y Proteus entre los bacilos gram negativos. Entre los cocos gram positivos fué el Estreptococo fe- calis el más frecuente, seguido del Estreptococo viridans y Estafilococo coagulasa positiva. Poca incidencia se observó de Estreptococo hemolítico, Neumococo y N. gonorrhoeae.
Las infecciones clínicas por anaerobios, estuvieron a cargo del Estreptococo, el cual produjo cuadros clínicos muy serios, que obligó al menos en uno, a la histerectomía total. Dos aislamientos de Clostridium welchii se consideraron como casuales o carentes de virulencia. Los estudios de patología y las evaluaciones clínicas conjuntas, permitieron hacer una serie de correlaciones. De esta manera el estudio patológico y el diagnóstico clínico estuvieron de acuerdo en el 76,1%, el cultivo con el patológico en el 73,1%, el clínico con el cultivo en el 67,0% y finalmente los tres en el 62,1%.
En los casos de autopsia se encontró siempre una explicación bacteriológica y/o patológica. La infección, en seis de ellos, se correlacionó completamente con los hallazgos de autopsia.
Pengaruh Pengolahan Tanah dan Penambahan Jerami terhadap Kebutuhan Air Penyiapan Lahan Padi Sawah
Authors: Yanti Delvi , Mandang Tineke , Purwanto Mohamad Yanuar Jawardi , Solahudin Mohamad 
Published: July 2020

Praktik manajemen seperti pengolahan tanah, mulsa, aplikasi pupuk dan pemupukan dilakukan untuk meningkatkan lingkungan fisik tanah dengan tujuan akhir untuk meningkatkan produktivitas tanaman. Tujuan penelitian ini adalah untuk mengetahui pengaruh pengolahan tanah dan penambahan jerami terhadap kebutuhan air penyiapan lahan padi sawah. Penelitian terdiri dari dua faktor perlakuan, yaitu pengolahan tanah dan penambahan jerami yang masing-masing dilakukan 3 kali. Metode pengolahan tanah yaitu pembajakan-pelumpuran dilakukan dengan dua tahap atau ada jeda selama 15 hari (PT1) dan pembajakan-pelumpuran dilakukan dalam satu tahap kegiatan atau tanpa ada jeda (PT2), sedangkan untuk perlakukan jerami, ada yang tanpa jerami (J0) dan menggunakan jerami (J1). Pengamatan dilakukan terhadap sifat fisik tanah dengan cara pengambilan contoh tanah utuh sebelum pengolahan tanah (SPT) dan setelah tanah diolah, perhitungan terhadap kebutuhan air penyiapan lahan dilakukan untuk masing-masing perlakuan. Untuk mengethaui pengaruh perlakuan terhadap sifat fisik tanah dilakukan dengan analisis statistik yaitu degan paried sample t-test. Hasil percobaan yaitu pengolahan tanah dan penambahan jerami berpengaruh terhadap sifat fisik tanah. Pengolahan tanah dua tahap dan penambahan jerami merupakan perlakuan yang membutuhkan air paling banyak dalam penyiapan lahan yaitu sebesar 196,95 mm, tetapi merupakan perlakuan terbaik dengan air tersedia sebesar 16 %.
Pengaruh Nilai Wajar Aset Biologis terhadap Manajemen Laba
Authors: Febryanti Vista , Sayekti Yosefa , Agustini Aisa Tri 
Published: July 2020

The purpose of this study is to examine and analyze the effect of the biological asset’s fair value on the earning management in the agroindustry companies that listed at the Indonesia Stock Exchange (BEI). This research is a quantitative study using secondary data from annual and quarterly reports of agroindustry companies 2018. This study uses the dependent variable earning management which is measured by Stubben’s model, independent variable biological asset’s fair value which is measured by gains or losses from the implementation of fair value to biological assets, and control variables firm size (logarithm of total assets) and leverage (DER). The results of this study shows that the biological asset’s fair value which is implemented through the PSAK 69: Agriculture has the positive effect on the earning management, and control variables (firm size and leverage) have no effect on earning management. This results indicates that the implementation of biological asset’s fair value through PSAK 69 in agroindustry companies enhances earning management action taken by manager.
Keywords: biological assets; earning management; fair value; PSAK 69.
Pengaruh Corporate Social Responsibility (CSR) Disclosure terhadap Profitabilitas Perusahaan
Authors: Wulandari Siti 
Published: July 2020

The purpose of this study is to examine and analyze the effect of Corporate Social Responsibility Disclosure on company profitability in plantation subsector companies that listed on the Indonesia Stock Exchange on 2016-2018. This research is a type of quantitative research that using secondary data, namely the annual report of the plantation subsector company 2016-2018. Independent variable that used in this research is CSR Disclosure which is measured using CSRDI and the dependent variable is company profitability which is proxied by the ratio of ROA, ROE, and NPM. The results show that CSR Disclosure have the positive and significant effect on ROA with a significance value of 0.012, ROE of 0.035, and NPM of 0.028. The results of this study indicate that empirically disclosing CSR activities in plantation subsector companies will increase company profitability.
Keywords: CSR Disclosure, NPM, ROA, ROE.
Faktor- Faktor yang Mempengaruhi Tingkat Bagi Hasil Deposito Mudharabah pada BMT Maslahah Se-Kabupaten Situbondo
Authors: Yulinartati Yulinartati , Probowulan Diyah , Putri Tara Ayu Adevia 
Published: July 2020

The level of profit sharing provided by Islamic banks is one of the public's attractions to store funds in Islamic banks, but at the profit sharing level. Because it still refers to conventional bank interest rates, people still think that Islamic banks are the same as conventional banks. This study aims to analyze the factors that influence the level of profit sharing of mudharabah deposits at BMT Maslahah in Situbondo Regency. The population used is the annual financial statements in the 5 Sub-District Regencies of Situbondo 2014-2019. The sample selection tested in this study used SPSS 20.0 software. Variables used in this study are Return on Assets (ROA), Capital Adequacy Ratio (CAR), Non Performing Financing (NPF), Financing to Deposits Ratio (FDR), BOPO (Operational Costs Operating Income). As an independent variable, and the level of profit sharing of mudharabah deposits as the dependent variable. Some of the results show that the Return on Assets (ROA), Financing to Deposits Ratio (FDR) have a positive effect on the profit sharing rate of mudharabah deposits while Capital Adequacy Ratio (CAR), Non Performing Financing (NPF), BOPO (Operational Cost of Operating Income) has a negative effect .
Keywords: Return on Assets (ROA), Capital Adequacy Ratio (CAR), Non Performing Financing (NPF), Financing to Deposits Ratio (FDR), BOPO (Operational Costs, Operating Income, Profit Sharing Rate for Mudharabah Deposits).
EFEKTIVITAS MODEL PEMBELAJARAN TERHADAP KETERAMPILAN MEMBACA KANJI
Authors: Setiawati Nia 
Published: July 2020

Abstract: This study aims to determine the effectiveness of the learning model of kanji reading skills. This research was conducted at the Departement of Japanese Language Education of The Faculty of Language and Art, Jakarta State University in the 2015/2016 academic year. The sample were 52 students, divided into a group of 26 students as an experimental class using Information Search instructional model (IS) and 26 students as a control class using Student Team Achievement Division instructional model (STAD).
The method used in this research was experimental method by using a factorial design of 2X2. The data were analyzed by using a Two-Factor ANAVA at the significance level a=0,01. The results of this research indicated that the IS model more effective than the STAD model.
Abstrak: Penelitian ini bertujuan untuk mengetahui efektifitas model pembelajaran keterampilan membaca kanji. Masalah yang diangkat pada penelitian ini ialah mahasiswa prodi sastra jepang belum memiliki keterampilan yang tinggi untuk mampu membaca kanji. Sehingga diperlukan upaya untuk meningkatkan keterampilan mahasiswa untuk membaca kanji. Pendidikan Penelitian ini dilakukan di Jurusan Pendidikan Bahasa Jepang Fakultas Bahasa dan Seni, Universitas Negeri Jakarta pada tahun ajaran 2015/2016. Sampel sebanyak 52 siswa, terbagi dalam kelompok 26 siswa sebagai kelas kontrol dengan menggunakan model instruksional Unit Prestasi Tim Siswa (STAD). Metode yang digunakan dalam penelitian ini adalah metode eksperimen dengan menggunakan desain faktorial 2X2. ANAVA pada tingkat signifikansi Î±= 0,01. Modelnya lebih efektif daripada model STAD.
Suture and Needle Characteristics in Orthopaedic Surgery
Authors: Pacer Elizabeth , Griffin Daniel W. , Anderson Ashley B. , Tintle Scott M. , Potter Benjamin K. 
Published: July 2020

Update
This article was updated on July 30, 2020, because of a previous error. On pages 1 and 11, in the byline section and author affiliation section, “Dan W. Griffith” now reads “Daniel W. Griffin,” and “D.W. Griffith” reads “D.W. Griffin.”
An erratum has been published: JBJS Reviews. 2020 Aug;8(8):e19.00133ER.

» There remains a dearth of research on and general knowledge with regard to materials used for wound closure and soft-tissue repair and approximation.» Critical suture properties include physical configuration, fluid absorption and capillarity, caliber or diameter, tensile strength, torsion, absorbability, elasticity, plasticity, memory, coefficient of friction, and knot security. The optimal ranges of each of these characteristics remain undefined for most sutures and indications.» Needle types and basic design characteristics affect suture passage and require further consideration with regard to specific suture-needle selection.» Suture must perform its intended purpose with a minimum of undesirable reaction and infectious potential, adequate duration of efficacy, and adequate strength. However, stronger, or high tensile strength, suture is not always better because of the requisite increase in suture caliber as well as the potential for inadvertent tissue strangulation, possibly increasing inflammatory reactivity. Sometimes, we seek stable, watertight fascial closure; occasionally, strong and durable tendon repair; and other times, gentle, cosmetically friendly, skin eversion and opposition. A variety of common suture types differ in these critical characteristics and may be optimally utilized for contrasting, but sometimes overlapping, indications.
The Prevalence of Metabolic Syndrome in Chinese Women over 50 Years Old Deserves More Attention
Authors: Jiao Yang , Xie Xuan , Zhang Chunhong , Ming Jie , Xu Shaoyong , Wang Yangwei , Yao Xiaoli , Jia Aihua , Li Hui , Sui Jing , Qin Jianjun , Li Wenjie , Zhang Haixiong , Zhao Xin , Ji Qiuhe 
Published: July 2020

Abstract
The authors have withdrawn this preprint due to author disagreement.
A dynamic in-vitro model of the intestinal epithelium for the investigation of P-glycoprotein activity
Authors: Costa Joana , Almonti Vanessa , Cacopardo Ludovica , Poli Daniele , Rapposelli Simona , Ahluwalia Arti 
Published: July 2020

Abstract
Multidrug resistance is still an obstacle for chemotherapeutic treatments. One of the proteins involved in this phenomenon is the P-glycoprotein, P-gp, which is known to be responsible for the efflux of therapeutic substances from the cell cytoplasm. To date, the identification of a drug that can efficiently inhibit P-gp activity remains a challenge, nevertheless some studies have identified natural compounds suitable for that purpose. Amongst them, curcumin has shown an inhibitory effect on the protein in in vitro studies using Caco-2 cells.To understand if physiological flow can modulate membrane protein activity, we studied the uptake of a P-gp substrate under static and dynamic conditions. Caco-2 cells were cultured in bioreactors and in Transwells and the basolateral transport of Rhodamine-123 assessed in the two systems as a function of P-gp activity. Experiments were performed with and without pre-treatment of the cells with an extract of curcumin or an arylmethyloxy-phenyl derivative to evaluate the inhibitory effect of the natural substance with respect to a synthetic compound.The results indicated that the P-gp activity of the cells cultured in the bioreactors was intrinsically lower, and that the effect of both natural and synthetic inhibitors was up modulated by the presence of flow. Our study underlies the fact that the use of more sophisticated and physiologically relevant in vitro models can bring new insights on the therapeutic effects of natural substances such as curcumin.
RNA-seq profiles of LPS-induced transcriptional changes in LBP-deficient rat and its possible implications for the liver dysregulation during sepsis
Authors: Song Zichen , He Zhixiang , Meng Leilei , Cheng Wenhui , Huang Fan , Zheng Mao , Xu Wenhui , Xiao Rong , Fang Haoshu , Zhu Yaling 
Published: July 2020

Abstract
Background

Sepsis is an organ dysfunction caused by the dysregulated inflammatory response to infection. LBP binds to LPS, and modulates the inflammatory response. Rare systematic study has been reported to detect the effect of LBP gene during the LPS-induced sepsis. Herein, we explored the RNA sequencing technology to profile the transcriptomic changes in liver tissue between LBP-deficient rats and WT rats at multiple timepoints after LPS administration.
Results

We compared the serum ALT levels using the biochemistry analyzer and proceeded RNA sequencing of liver tissue to search differentially expressed genes and enriched biological processes and pathways between LBP-deficient and WT groups at 0 h, 6 h, and 24 h. In total, 168, 284, and 307 differential expressed genes (DEGs) were identified at 0 h, 6 h, and 24 h respectively, including Lrp5, Cyp7a1, Nfkbiz, Sigmar1, Fabp7, and Hao1, which are related to the inflammatory or lipid-related process. Functional enrichment analysis revealed that inflammatory response to LPS mediated by Ifng, Cxcl10, Serpine1, and Lbp was enhanced at 6 h, while lipid-related metabolism associated with C5, Cyp4a1, and Eci1 was enriched at 24 h after LPS administration in the WT samples. The inflammatory process was not found when the LBP gene was knocked out, lipid-related metabolic process and PPAR signaling pathway mediated by Dhrs7b and Tysnd1 were significantly activated in LBP-deficient samples.
Conclusions

Our study suggested that the invading LPS may interplay with LBP to activate NF-κB signaling pathway and trigger uncontrolled inflammatory response. However, when inhibiting the activity of NF-κB, lipid-related metabolism would make bacteria removal via the effect on PPAR signaling pathway in the absence of LBP gene. Moreover, we further found the potent implications of targeting the LBP gene may as a biomarker for inflammatory conditions induced by metabolic disorders.
Inhibitory Effects of the Spore-forming Bacillus spp. on the Expression Levels of eae, luxS, flu, and ctxM Genes in E. coli Isolates
Authors: Elahianfiroz Zahra , baserisalehi majid , Ghane masood 
Published: July 2020

Abstract
Background: Escherichia coli antibiotic resistance are one of the major health problems in many countries. Today, researchers are focusing on novel approaches for the treatment of E. coli infections, including the use of spore-forming probiotics for their high stability in the harsh gastrointestinal (GIT) environment. Results: The presence of resistance genes (flu, eae, luxS, and ctxM ) was confirmed by PCR in four out of 40 E. coli isolated from 300 fecal samples of patients suffering from diarrhea. Following confirming the ability of broiler-derived Bacillus coagulans and Bacillus subtilis to survive under the simulant gastric environment, they were co-cultured with the four E. coli isolates harboring the studied resistance genes. Results of the expression of flu, luxS, eae, and ctxM genes revealed that the expression levels of these genes decreased significantly (p-value < 0.05) after co-culture of E. coli with B. subtilis ATCC 6633 and broiler-derived B. subtilis. However, the broiler-derived B. subtilis showed a greater effect on the expression levels of eae, luxS, and ctxM. B. coagulans MTCC 5856 and broiler-derived B. coagulans also led to significant decreases in expression levels of all the studied genes (p-value < 0.05), while the standard strain had a greater impact on the expression of ctxM than the broiler-derived strains.Conclusion: The broiler-derived isolates had a greater capacity to decrease the expression of these genes than the standard strains, proposing their adoption for dietary supplementations. However, further studies are required to study the effects of these spore-forming bacteria on E. coli infections in vivo and their possible influence on lactose tolerance, nutritional absorption, and reduced cholesterol levels.
Mortality risk in people with type 2 diabetes: a large prospective population-based cohort study (The Ayrshire Diabetes fOllow-up Cohort (ADOC) study)
Authors: Collier Andrew , Hair Mario , Cameron Lyall , Ghosh Sujoy , Boyle James , Walters Matthew , Waugh Norman 
Published: July 2020

Abstract
BackgroundThe aims of this study were to investigate the effects of age, gender, body mass index (BMI), glycaemic control, socio-economic status, dyslipidaemia, hypertension, ischaemic heart disease (IHD) and smoking status in type 2 diabetes in a population-based analysis. MethodsData were collected from 46 General Practice databases in 2009 and 2014. Cox regressions were run in the non-diabetes population plus type 2 diabetes patients. ResultsPeople with type 2 diabetes (n=16,643) had higher mortality rates than non-diabetes subjects. Ranked in order of Hazard Ratio (HR), increasing age (HR 2.31), smoking (HR 1.79), IHD (HR 1.65), deprivation (HR 1.36), hypertension (HR 1.23) and male gender (HR 1.20) all increased mortality risk (p<0.01). Statin therapy was associated with better outcome (HR 0.65, p<0.01). Abnormal lipid levels whilst not on a statin significantly increased mortality risk for raised total-cholesterol (HR 1.74) and low HDL-cholesterol (HR 1.48) but not for triglycerides (HR 0.67) (all p<0.01). ConclusionsThis large study confirmed that the all-cause mortality risk in people with type 2 diabetes remains elevated. In the study we demonstrated that a man with type 2 diabetes of 5-10 years duration who smoked, had hypertension and IHD plus lived in the most deprived area had a HR of 6.2 compared with a non-smoking, normotensive, non-diabetes subject without IHD living in the least deprived area. . Further research is required to understand the gender risk difference in all-cause mortality in type 1 compared with type 2 diabetes and why obesity plus raised triglycerides appear to be protective.
Hepatokine ERAP1 impairs skeletal muscle insulin sensitivity via ADRB2/PKA pathway
Authors: Guo Feifan , Niu Yuguo , Jiang Haizhou , Yin Hanrui , Wang Fenfen , Hu Xiaoming , Chen Shanghai 
Published: July 2020

Abstract
The current study aimed to investigate the role of endoplasmic reticulum aminopeptidase 1 (ERAP1), a novel hepatokine, in whole-body glucose metabolism. Here, we found that hepatic ERAP1 levels were increased in insulin-resistant leptin-receptor-mutated (db/db) and high-fat diet (HFD)-fed mice. Consistently, hepatic ERAP1 overexpression attenuated skeletal muscle (SM) insulin sensitivity, whereas knockdown ameliorated SM insulin resistance. Furthermore, serum and hepatic ERAP1 levels were positively correlated, and recombinant mouse ERAP1 or conditioned medium with high ERAP1 content (CM-ERAP1) attenuated insulin signaling in C2C12 myotubes, and CM-ERAP1 or HFD-induced insulin resistance was blocked by ERAP1 neutralizing antibodies. Mechanistically, ERAP1 reduced ADRB2 expression and interrupted ADRB2-dependent signaling in C2C12 myotubes. Finally, ERAP1 inhibition via global knockout or the inhibitor thimerosal improved insulin sensitivity. Together, ERAP1 is a hepatokine that impairs SM and whole-body insulin sensitivity, and its inhibition might provide a therapeutic strategy for diabetes, particularly for those with SM insulin resistance.