bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pushover analysis for flexible and semi‐flexible pile‐supported wharf structures accounting the dynamic magnification factors due to torsional effects
Authors: Zacchei Enrico , Lyra Pedro H. C. , Stucchi Fernando R. 
Published: September 2020

AbstractThis is a pushover analysis for pile‐supported wharves considering the dynamic magnification factors due to torsional effects. The piles seismic design by deterministic approach is shown accounting plastic hinges and P‐delta effects in 2D/3D mathematical modeling. A real structure placed at high seismicity area is considered as case study in order to validate the model and provide reliable technical data. New bound limits of seismic demands associated with damage states and the best soil performance are identified. A stochastic approach is proposed to estimate the no‐exceedance probability of horizontal displacements of a semi‐flexible with respect to a flexible model. Results are plotted in terms of base shears, displacements, and energy. The advantage of the use of pushover analysis in terms of displacements is estimated in 18–38%. Other results as bound limits, hysteretic damping, plastic rotation are compared with previous studies.
Decoupling the strength and drift criteria in steel moment‐resisting frames
Authors: Ahlehagh Sanaz , Mirghaderi Seyed Rasoul 
Published: September 2020

SummarySuperior ductility of moment‐resisting frames allows for high response modification factors, therefore design for smaller earthquake loads. In contrast, to limit the lateral drift, the cross‐sectional dimensions of the beams and columns are increased, which deactivates the benefits of the achieved high response modification factor. The linked beam frame system is proposed in this paper to decouple the strength and drift criteria. The link elements are added between the beams of two adjacent stories in spans where allowed architecturally to control the drift while they also increase the potential sources of energy dissipation. The design procedure is straightforward and prevents the trial and error analysis required for conventional moment‐resisting frames. The effect of the links on the lateral stiffness of the structure is estimated, and prototype buildings of five, 10, and 15 stories are investigated using linear and nonlinear analyses. A comparison of the results between the proposed system and the conventional method indicates that in addition to simplification of the design procedure, saving of about 10% to 15% in steel material of each lateral load resisting frame is achieved.
Sichere R0-Resektion zur Vermeidung der adjuvanten Therapieeskalation beim Oropharynxkarzinom
Authors: Mansour N. , Backes C. , Becker C. , Hofauer B. , Knopf A. 
Published: September 2020

Zusammenfassung
Hintergrund
Der Resektionsstatus ist ein Prädiktor bei Patienten mit Oropharynxkarzinomen (OPSCC) für die Überlebensrate (ÜR) und das rezidivfreie Überleben (RFÜ). TNM-Status, extrakapsuläres Wachstum im Lymphknoten (ECE) und der Resektions(R)-Status des Primärtumors entscheiden über die adjuvante Therapie, wobei der R‑Status unmittelbar durch den Kopf-Hals-Chirurgen beeinflussbar ist. Ziel dieser Arbeit ist die Evaluation des Einflusses des R‑Status auf Therapieentscheidungen, RFÜ und ÜR.

Material und Methoden
Es wurden alle Patienten mit Plattenepithelkarzinom des Oropharynx, die im Zeitraum von 2001–2011 operiert wurden, in die Auswertung eingeschlossen. Retrospektiv wurden klinische Parameter, Überlebensdaten, histologische Daten wie ECE, R‑Status und Tumorausdehnung erhoben sowie analysiert.

Ergebnisse
Es wurden 208 Patienten in die Studie eingeschlossen. Patienten mit R0-Resektion zeigten ein mittleres RFÜ/ÜR von 89/87 Monaten. Dieses sank signifikant bei Patienten mit R1-Resektion (65/65 Monate), R2-Resektion (38/33 Monate) sowie Rx-Resektion (59/45 Monate; p = 0,036/p = 0,001). Bei Patienten mit ECE und R1-Resektion, aber auch mit R0-Resektion durch Nachresektion und Rx-Status erfolgte eine adjuvante Therapieeskalation.

Schlussfolgerung
Unsichere Resektionsränder reduzieren das RFÜ und die ÜR. Daher sollte bei einer chirurgischen Therapie immer eine R0-Resektion möglichst am Hauptpräparat angestrebt werden, um eine adjuvante Therapieeskalation wegen eines unklarer R‑Status zu vermeiden.
Multi-domain optimization of the eigenstructure of controlled underactuated vibrating systems
Authors: Belotti Roberto , Richiedei Dario , Trevisani Alberto 
Published: September 2020

AbstractThe paper proposes a multi-domain approach to the optimization of the dynamic response of an underactuated vibrating linear system through eigenstructure assignment, by exploiting the concurrent design of the mechanical properties, the regulator and state observers. The approach relies on handling simultaneously mechanical design and controller synthesis in order to enlarge the set of the achievable performances. The underlying novel idea is that structural properties of controlled mechanical systems should be designed considering the presence of the controller through a concurrent approach: this can considerably improve the optimization possibilities. The method is, first, developed theoretically. Starting from the definition of the set of feasible system responses, defined through the feasible mode shapes, an original formulation of the optimality criterion is proposed to properly shape the allowable subspace through the optimal modification of the design variables. A proper choice of the modifications of the elastic and inertial parameters, indeed, changes the space of the allowable eigenvectors that can be achieved through active control and allows obtaining the desired performances. The problem is then solved through a rank-minimization with constraints on the design variables: a convex optimization problem is formulated through the “semidefinite embedding lemma” and the “trace heuristics”. Finally, experimental validation is provided through the assignment of a mode shape and of the related eigenfrequency to a cantilever beam controlled by a piezoelectric actuator, in order to obtain a region of the beam with negligible oscillations and the other one with large oscillations. The results prove the effectiveness of the proposed approach that outperforms active control and mechanical design when used alone.
Study of the K-S distance on skulls from different modern populations for sex and ancestry determination
Authors: Jellinghaus K. , Matin S. , Urban P. , Bohnert M. , Jantz R. 
Published: September 2020

AbstractIn forensic science determination of the origin and sex of skeletal remains is an important task for identification purposes. In this study we investigated the krotaphion-sphenion distance (K‑S distance) in the pterion region of German, Euro-American, African-American and Rwandan skulls of modern individuals from the nineteenth to the twenty-first century to look for statistically significant differences in sex and ancestry. We found a statistically significant sex-specific difference in the K‑S distance, which was greater in male skulls than in female skulls for both sides of the skull. Our study also showed that there is a statistically significant difference in the K‑S distance between the four populations studied. Landmarks and morphometric parameters measured in our investigations, which were not used for the present examination were provided to the software program Fordisc for its reference data to enhance the range of its usability for identification of unknown skulls or partial skulls of European individuals.
Pattern of SQSTM1 Gene Variants in a Hungarian Cohort of Paget’s Disease of Bone
Authors: Donáth Judit , Balla Bernadett , Pálinkás Márton , Rásonyi Rita , Vastag Gyula , Alonso Nerea , Prieto Beatriz Larraz , Vallet Mahéva , Ralston Stuart H. , Poór Gyula 
Published: September 2020

AbstractPaget’s disease of bone (PDB) is characterized by focal or multifocal increase in bone turnover. One of the most well-established candidate genes for susceptibility to PDB is Sequestosome 1 (SQSTM1). Mutations in SQSTM1 have been documented among Western-European, British and American patients with PDB. However, there is no information on SQSTM1 mutation status in PDB patients from the Central- and Eastern-European regions. In this study, we conducted a mutation screening for SQSTM1 gene variants in 82 PDB patients and 100 control participants in Hungary. Mutations of SQSTM1 were detected in 18 PDB patients (21.95%); associations between genotype and clinical characteristics were also analyzed. Altogether, six different exonic alterations, including two types of UTR variants in the SQSTM1 gene, were observed in our PDB patients. Similarly, to previous genetic studies on Paget’s disease, our most commonly detected variant was the c.1175C > T (p.Pro392Leu) in nine cases (four in monostotic and five in polyostotic form). We have surveyed the germline SQSTM1 variant distribution among Hungarian patients with PDB. We also highlighted that the pattern of the analyzed disease-associated pathophysiological parameters could partially discriminate PDB patients with normal or mutant SQSTM1 genotype. However, our findings also underline and strengthen that not solely SQSTM1 stands in the background of the complex PDB etiology.
Early Enteral Nutrition Could Reduce Risk of Recurrent Leakage After Definitive Resection of Anastomotic Leakage After Colorectal Cancer Surgery
Authors: Tian Weiliang , Xu Xin , Yao Zheng , Yang Fan , Huang Ming , Zhao Risheng , Zhao Yunzhao 
Published: September 2020

AbstractBackgroundThe present study aimed to evaluate the effect of early enteral nutrition (EEN) after definitive resection of anastomotic leakage (DRAL) resulting from a sigmoid colon or rectal cancer radical resection.MethodsThis was a prospective cohort study performed at our center. From January 2014 to May 2016, every patient received a standard postoperative nutritional protocol (SPNP) after DRAL and was included into SPNP group. From June 2016 to December 2018, all patients received an EEN after DRAL and were included into EEN group. The effect of postoperative EEN was evaluated.ResultsThere were a final total of 133 patients enrolled in our study. There were 70 patients in the SPNP group, and 63 patients in the EEN group. There were 12 cases (19.05%) with a recurrent leakage in the EEN group, and 28 cases (40%) in the SPNP group. The recurrent rate was associated with EEN (HR = 0.417, 95% CI 0.196–0.890, p = 0.024). The median defecation time in the EEN group was 5(4–7) days, while in the SPNP group was 7(6–8.25) days. The defecation was associated with EEN (HR = 1.588, 95% CI 1.080–2.336, p = 0.019), as well.ConclusionEEN could reduce the recurrent leakage rate and defecation time after definitive resection of anastomotic leakage resulting from sigmoid colon or rectal cancer radical resection.
Malrotation Correction in the Adult Population
Authors: Brungardt Joseph G. , Liebscher Sean C. , Schropp Kurt P. 
Published: September 2020

AbstractBackgroundMalrotation is a congenital anomaly most often affecting the pediatric population. The Ladd procedure is the standard treatment for this pathology. Well‐studied in the pediatric population, large studies of the demographics and outcomes of patients who reach adulthood are lacking.MethodsAn analysis of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database (2015–2018) was performed, capturing patients with a post‐operative diagnosis of malrotation and who underwent surgical correction with or without appendectomy, excluding those who underwent other major procedures such as colectomy. Baseline demographics and outcomes were compared. The primary outcome was mortality. Secondary outcomes such as length of stay and discharge destination were included.ResultsTwo hundred twenty patients undergoing surgical correction of malrotation were captured, all of which were performed by a general surgeon under general anesthesia. One hundered and nine (49.55%) of these patients also underwent an appendectomy. Most of these patients were female (68.18%). Comorbidities and perioperative variables were clinically similar. Operative time was similar between the two groups (112 ± 86 vs. 98 ± 49 min, p = 0.1385). Thirty‐day mortality (1.36%), length of stay (4.79 ± 6.21 days), readmission rate (13.64%), wound infection (2.27%) and discharge destination (95.00% to home) were statistically similar between groups.ConclusionsThe data describes demographics and outcomes in adults undergoing Ladd procedures with and without appendectomy. Immediate outcomes may be equivalent regardless of incidental appendectomy. Further work is necessary to describe the population of adults with malrotation reaching adulthood.
Outcome Predictors in Civilian and Iatrogenic Arterial Trauma
Authors: Kakkos Stavros K. , Tyllianakis Minos , Panagopoulos Andreas , Kokkalis Zinon , Lianou Ioanna , Koletsis Efstratios , Tsolakis Ioannis , Papadoulas Spyros , Gliatis John , Maroulis Ioannis , Kitrou Panagiotis 
Published: September 2020

AbstractBackgroundOur aim was to identify predictors of mortality and limb loss in iatrogenic and civilian arterial trauma.MethodsCases were identified by searching prospectively maintained registries. Multivariable logistic regression was used to identify independent outcome predictors.ResultsDuring the study period, 285 patients with arterial trauma were managed with endovascular (n = 20) or open (n = 265) repair. Iatrogenic injuries increased in frequency during the course of the study, from 23.9% during the first decade to 35.9 and 55.7% during the second and third decade, respectively (p < 0.001). Endovascular management increased in frequency during the course of the study, from 0% during the first decade to 5.1 and 11.1% during the second and third decade, respectively (p = 0.005). Mortality was 9.8%, and limb loss (in cases with injury of the aorta or limb arteries, n = 259) was 6.2%. Independent predictors of mortality included increased age (odds ratio, 95% confidence interval [OR, 95% CI] 1.05 (1.02–1.07), p < 0.001), blunt trauma (OR [95% CI] 4.8 (1.9–12.2), p = 0.001) and the number of RBC units transfused intraoperatively (OR [95% CI] 1.25 (1.1–1.4), p = 0.001). Independent predictors of limb loss included the first half of the study period (OR [95% CI] 3.9 (1.1–14.1), p = 0.04), lower extremity arterial trauma (vs upper extremity, aortic, common or external iliac artery trauma, OR [95% CI] 8.3 (1.9–35.7), p = 0.004), bone fracture (OR [95% CI] 16.9 (4.7–62.5), p < 0.001) and the number of RBC units transfused intraoperatively (OR [95% CI] 1.16 (1.02–1.33), p = 0.024).ConclusionIncreasingly iatrogenic in cause and managed by endovascular methods, arterial trauma remains a problem associated with significant mortality and limb loss. Identification of unfavourable outcome predictors may help clinicians involved with arterial trauma to escalate the level of care.
The Current Landscape of Staging and Treatment of Colorectal Cancer in a Region of Ukraine: a Mixed Methods Study
Authors: Lu Pamela W. , Shabat Galyna , Semeniv Solomiia , Fedorkiv Maryana , Fields Adam C. , Lyu Heather G. , Beznosenko Andriy , Davids Jennifer S. , Melnitchouk Nelya 
Published: September 2020

AbstractBackgroundIn Ukraine, the 1‐year mortality for colorectal cancer is much higher than that seen in high‐income countries. We investigated practice patterns of colorectal cancer treatment in a region of Ukraine to account for high mortality rates.MethodsAn explanatory sequential mixed methods design was used. Data from patients who underwent surgery for colorectal cancer in Ivano‐Frankivsk from 2011 to 2015 were collected via retrospective chart review, and descriptive statistics were calculated. Semi‐structured interviews were performed with local practicing surgeons and oncologists until thematic saturation was reached.ResultsA total of 960 patients who underwent surgery were identified in the Ivano‐Frankivsk region with colon (689) or rectal (271) cancer. 11.7% of patients underwent preoperative CT of the abdomen and pelvis, and only 1.7% underwent CT of the chest. 4.1% of patients underwent a complete preoperative colonoscopy, while 31.0% had incomplete colonoscopies. Postoperatively, 31.1% of patients with stage II colon cancer and 43.9% of patients with stage III colon cancer underwent adjuvant chemotherapy. For patients with stage II and III rectal cancers, 20.9% and 33.3% underwent chemotherapy, while 68.4% and 66.7% underwent radiation therapy, respectively. Fifteen physicians completed interviews. Two major themes emerged regarding physician perceptions on providing colorectal cancer care: lack of resources and systems level issues negatively impacting patient care.ConclusionIn this region in Ukraine, staging practices for colorectal malignancies are inconsistent and inadequate, and adjuvant treatments are varied. This is likely attributable to the lack of resources facing providers and the prohibitively high cost of care to patients.
Magnetoreception in Hymenoptera: importance for navigation
Authors: Fleischmann Pauline N. , Grob Robin , Rössler Wolfgang 
Published: September 2020

AbstractThe use of information provided by the geomagnetic field (GMF) for navigation is widespread across the animal kingdom. At the same time, the magnetic sense is one of the least understood senses. Here, we review evidence for magnetoreception in Hymenoptera. We focus on experiments aiming to shed light on the role of the GMF for navigation. Both honeybees and desert ants are well-studied experimental models for navigation, and both use the GMF for specific navigational tasks under certain conditions. Cataglyphis desert ants use the GMF as a compass cue for path integration during their initial learning walks to align their gaze directions towards the nest entrance. This represents the first example for the use of the GMF in an insect species for a genuine navigational task under natural conditions and with all other navigational cues available. We argue that the recently described magnetic compass in Cataglyphis opens up a new integrative approach to understand the mechanisms underlying magnetoreception in Hymenoptera on different biological levels.
Clinical assessment of gait and functional mobility in Italian healthy and cognitively impaired older persons using wearable inertial sensors
Authors: Mulas Ilaria , Putzu Valeria , Asoni Gesuina , Viale Daniela , Mameli Irene , Pau Massimiliano 
Published: September 2020

Abstract
Aim
The main purpose of the present study was to verify the feasibility of wearable inertial sensors (IMUs) in a clinical setting to screen gait and functional mobility in Italian older persons. In particular, we intended to verify the capability of IMUs to discriminate individuals with and without cognitive impairments and assess the existence of significant correlations between mobility parameters extracted by processing trunk accelerations and cognitive status.

Methods
This is a cross-sectional study performed on 213 adults aged over 65 years (mean age 77.0 ± 5.4; 62% female) who underwent cognitive assessment (through Addenbrooke’s Cognitive Examination Revised, ACE-R) instrumental gait analysis and the Timed Up and Go (TUG) test carried out using a wearable IMU located in the lower back.

Results
Individuals with cognitive impairments exhibit a peculiar gait pattern, characterized by significant reduction of speed (− 34% vs. healthy individuals), stride length (− 28%), cadence (− 9%), and increase in double support duration (+ 11%). Slight, but significant changes in stance and swing phase duration were also detected. Poorer performances in presence of cognitive impairment were observed in terms of functional mobility as overall and sub-phase TUG times resulted significantly higher with respect to healthy individuals (overall time, + 38%, sub-phases times ranging from + 22 to + 34%), although with some difference associated with age. The severity of mobility alterations was found moderately to strongly correlated with the ACE-R score (Spearman’s rho = 0.58 vs. gait speed, 0.54 vs. stride length, 0.66 vs. overall TUG time).

Conclusion
The findings obtained in the present study suggest that wearable IMUs appear to be an effective solution for the clinical assessment of mobility parameters of older persons screened for cognitive impairments within a clinical setting. They may represent a useful tool for the clinician in verifying the effectiveness of interventions to alleviate the impact of mobility limitations on daily life in cognitively impaired individuals.
Research on the design of smart morphing long-endurance UAVs
Authors: Ma T. , Liu Y. , Yang D. , Zhang Z. , Wang X. , Hao S. 
Published: September 2020

ABSTRACTTo improve the endurance performance of long-endurance Unmanned Aerial Vehicles (UAVs), a smart morphing method to adjust the UAV and flight mode continuously during flight is proposed. Using this method as a starting point, a smart morphing long-endurance UAV design is conducted and the resulting improvement in the endurance performance studied. Firstly, the initial overall design of the smart morphing long-endurance UAV is carried out, then the morphing form is designed and various control parameters are selected. Secondly, based on multi-agent theory, an architecture for the smart morphing control system is built and the workflow of the smart morphing control system is planned. The morphing decision method is designed in detail based on the particle swarm optimisation algorithm. Finally, a simulation of the smart morphing approach in the climb and cruise stages is carried out to quantitatively verify the improvement in the endurance performance. The simulation results show that the smart morphing method can improve the cruise time by 4.1% with the same fuel consumption.
Coronary artery aneurysm and facial drooping in a infant with Kawasaki disease
Authors: Yuan Ye , Lu Na 
Published: September 2020

AbstractKawasaki disease is the leading cause of acquired heart disease in infants and young children. Kawasaki disease that manifests as facial nerve palsy is extremely rare, and the diagnosis is challenging. We report a 4-month-old girl with Kawasaki disease who presented with fever, redness and cracking in the lips and oral cavity, and a right facial nerve palsy. The infant received intravenous immunoglobulin, acetyl salicylic acid, and warfarin. The patient’s fever subsided on the following day, and the right-sided facial nerve palsy was relieved a month later.