bluuebunny/crossref_metadata_2025_split huggingface dataset:
VV 655 and NGC 4418: Implications of an interaction for the evolution of a LIRG
Authors: Boettcher Erin , Gallagher III John S. , Ohyama Youichi , Varenius Eskil , Aalto Susanne , Falstad Niklas , König Sabine , Sakamoto Kazushi , Yoast-Hull Tova M. 
Published: March 2020

Context. VV 655, a dwarf irregular galaxy with HI tidal debris, is a companion to the lenticular luminous infrared galaxy (LIRG) NGC 4418. NGC 4418 stands out among nearby LIRGs due to its dense central concentration of molecular gas and the dusty, bi-polar structures along its minor axis suggestive of a wind driven by a central starburst and possible nuclear activity.
Aims. We seek to understand the consequences of the ongoing minor interaction between VV 655 and NGC 4418 for the evolution of the LIRG. Specifically, we consider the origin of the gas supply responsible for the unusual nuclear properties of NGC 4418.
Methods. We investigate the structural, kinematic, and chemical properties of VV 655 and NGC 4418 by analyzing archival imaging data and optical spectroscopic observations from the SDSS-III and new spectra from SALT-RSS. We characterize their gas-phase metal abundances and spatially resolved, ionized gas kinematics to better understand whether gas transfer between VV 655 and NGC 4418 resulted in the highly obscured nucleus of the LIRG.
Results. The gas-phase metallicity in NGC 4418 significantly exceeds that in VV 655. No kinematic disturbances in the ionized gas are observed along the minor axis of NGC 4418, but we see evidence for ionized gas outflows from VV 655 that may increase the cross-section for gas stripping in grazing collisions. A faint, asymmetric outer arm is detected in NGC 4418 of the type normally associated with galaxy-galaxy interactions.
Conclusions. The simplest model suggests that the minor interaction between VV 655 and NGC 4418 produced the unusual nuclear properties of the LIRG via tidal torquing of the interstellar medium of NGC 4418 rather than through a significant gas transfer event. In addition to inducing a central concentration of gas in NGC 4418, this interaction also produced an enhanced star formation rate and an outer tidal arm in the LIRG. The VV 655-NGC 4418 system offers an example of the potential for minor collisions to alter the evolutionary pathways of giant galaxies.
Characterization of the June epsilon Ophiuchids meteoroid stream and the comet 300P/Catalina
Authors: Matlovič Pavol , Kornoš Leonard , Kováčová Martina , Tóth Juraj , Licandro Javier 
Published: March 2020

Aims. Prior to 2019, the June epsilon Ophiuchids (JEO) were known as a minor unconfirmed meteor shower with activity that was considered typically moderate for bright fireballs. An unexpected bout of enhanced activity was observed in June 2019, which even raised the possibility that it was linked to the impact of the small asteroid 2019 MO near Puerto Rico. Early reports also point out the similarity of the shower to the orbit of the comet 300P/Catalina. We aim to analyze the orbits, emission spectra, and material strengths of JEO meteoroids to provide a characterization of this stream, identify its parent object, and evaluate its link to the impacting asteroid 2019 MO.
Methods. Our analysis is based on a sample of 22 JEO meteor orbits and four emission spectra observed by the AMOS network at the Canary Islands and in Chile. The meteoroid composition was studied by spectral classification based on relative intensity ratios of Na, Mg, and Fe. Heliocentric orbits, trajectory parameters, and material strengths were determined for each meteor and the mean orbit and radiant of the stream were calculated. The link to potential parent objects was evaluated using a combination of orbital-similarity D-criteria and backwards integration of the orbit of comet 300P and the JEO stream.
Results. We confirm the reports of an unexpected swarm of meteoroids originating in the JEO stream. JEO meteoroids have low material strengths characteristic for fragile cometary bodies, and they exhibit signs of a porous structure. The emission spectra reveal slightly increased iron content compared to all other measured cometary streams, but they are generally consistent with a primitive chondritic composition. Further dynamical analysis suggests that the JEO stream is likely to originate from comet 300P/Catalina and that it was formed within the last 1000 yr. Over longer timescales, the meteoroids in the stream move to chaotic orbits due to the turbulent orbital evolution of the comet. Our results also suggest that the impact of the small asteroid 2019 MO on June 22 was not connected to the JEO activity.
Le temps du traumatisme. Reconstruire l’espace de la transmission
Authors: Krischek Chantal 
Published: March 2020

En faisant taire l’histoire familiale, le traumatisme porte atteinte à ce qui fait la spécificité de chaque famille : sa capacité à transmettre. La transmission ne se déroule plus dans ce mouvement incessant entre le récit et son questionnement mais devient un système purement répétitif au sein duquel les croyances évolutives se transforment en dogmes disant le « tout » de l’individu.
Dans ce contexte, l’auteure propose une lecture de différents symptômes au regard du traumatisme familial. Elle décrit, au travers d’une élaboration conceptuelle illustrée par des cas cliniques, son chemin thérapeutique qui est un remaillage collectif de l’histoire familiale. Il s’agit de (re)construire l’espace potentiel de la transmission comme un lieu comprenant suffisamment d’indétermination que pour faire surgir, à chaque génération, de l’inédit et de l’inattendu.
Le nouveau cadre proposé délimite un espace thérapeutique regroupant plusieurs générations. Grâce à la rencontre dans l’espace partagé et au travail des mémoires individuelles, les générations différentes font l’expérience commune de l’histoire qui les a précédées. La conversation familiale prend forme, rendant possible la construction du récit commun.
La trace anti-mnésique. Hypothèses sur le traumatisme psychique chez l’enfant
Authors: Marcelli Daniel 
Published: March 2020

Exception faite du bébé et du très jeune enfant, le traumatisme psychique chez un enfant, si on veut bien prendre en considération ses modes particuliers d’expression tels que le jeu ou le dessin ne diffère pas fondamentalement dans son expression sémiologique de celui de l’adulte. Dans l’un et l’autre cas, on retrouve les mêmes termes pour décrire ce que la victime a subi au point qu’on peut en proposer un glossaire ! De même chez l’enfant comme chez l’adulte, la répétition, parfois compulsive, fait de cet événement unique quelque chose qui tend à se répéter, ce qui pose au psychiatre une énigme majeure laquelle conduisit S. Freud le premier à remanier sa théorie des pulsions. Car si parfois la trace de ce traumatisme peut, après coup, subir l’effet d’un refoulement et se transformer en symptôme, dans d’autres cas elle semble persister intangible chez l’individu quand ce n’est pas dans sa descendance ! Comment comprendre l’effet de cette trace laissée dans le fonctionnement neurocognitif sans pour autant qu’elle puisse faire l’objet d’une transformation psychique ? C’est ce qu’on observe tout particulièrement dans les traumatismes qui affectent les très jeunes enfants, à un âge où, encore dépourvus de langage, ils semblent prisonniers de cette incapacité d’élaboration. L’auteur propose de nommer celle-ci « trace anti-mnésique » car précisément le travail de la mémoire ne peut s’effectuer. Ces distinctions ne sont pas seulement académiques car elles ont un intérêt majeur dans l’orientation des soins, l’auteur opposant la lacune énigmatique sur laquelle un travail associatif peut s’effectuer, à la « trace anti-mnésique » où ce travail risque fort d’être voué à l’échec s’il n’est pas relayé par un accompagnement au plus près des perceptions sensorielles.
Die zwei Quellen des Sinns: Eine Kritik der psychiatrischen Hermeneutik in Anknüpfung an Schleiermacher
Authors: Brücher Klaus 
Published: March 2020

Zusammenfassung
Einleitung Die psychiatrische Hermeneutik bedenkt einzig den subjektiven Sinn und übersieht damit eine ganze Sinndimension, den von Schleiermacher so genannten „grammatischen Sinn“, der autonom – gemäß den Regeln von Sprache und Sozialität – generiert wird.
Methode Am Leitfaden von drei Postulaten in Schleiermachers Hermeneutik wird die Problemstellung entfaltet: Dass zwei Sinndimensionen – subjektiver und grammatischer Sinn – angenommen werden müssen, diese strikt voneinander zu unterscheiden sind, gleichwohl nur in ihrem „Ineinandersein“ Verstehen gewährleisten. Wo Schleiermacher im Wesentlichen auf eine philologische Deutung der grammatischen Sinndimension verwiesen war, stehen uns fast 200 Jahre später Optionen zur Verfügung, die allererst das in dieser Dimension enthaltene Potenzial auszuschöpfen erlauben.
Schlussfolgerungen Wird Sinn als ein in der Interaktion Zug um Zug sich herstellendes Produkt begriffen, verändern sich die Perspektive und mit ihr die hergebrachten Auffassungen grundlegend: Bedeutung wird dann zwischen den Interaktanden generiert, mithin nicht in ihnen, weder in ihrer Seele noch in ihrem Gehirn.Erst eine Konzeptualisierung, die das Medium von Sprache und Sozialität in seiner Eigengesetzlichkeit zum ersten Gegenstand des Verstehens macht, kann verständlich machen, was wir im Verstehen tatsächlich verstehen: Sinn – als die Art und Weise, wie ein Subjekt sich im Medium von Sprache und Sozialität selbst reproduziert.
Infizierte Urachuszyste beim Erwachsenen, Manifestation als Urosepsis
Authors: Albarghouth Mohamad Hatem , Dober Susanne , Kramer Thomas , Hamza Amir 
Published: March 2020

ZusammenfassungIm Nachfolgenden wird der Fall eines 81-jährigen Patienten dargestellt. Dieser stellte sich akut über die Notaufnahme unseres Hauses unter dem Bild einer Urosepsis bei Harnblasenkatheter-pflichtiger benigner Prostatahyperplasie vor. Im Rahmen der weiterführenden Diagnostik konnte eine infizierte Urachuszyste als ursächlicher Fokus festgestellt werden. Es erfolgte die chirurgische Therapie der infizierten Urachuszyste.
Vasorelaxant and Antihypertensive Effects of Neferine in Rats: An In Vitro and In Vivo Study
Authors: Wicha Piyawadee , Onsa-ard Amnart , Chaichompoo Waraluck , Suksamrarn Apichart , Tocharus Chainarong 
Published: March 2020

AbstractThe present study was performed to examine the antihypertensive effect of neferine in hypertensive rats and its relaxant mechanisms in isolated rat thoracic aorta. The antihypertensive effect was evaluated by tail-cuff methods on NG-nitro-L-arginine methyl ester (L-NAME) (40 mg/kg BW) 4-week hypertensive-induced hypertensive rats. The vasorelaxant effect and its mechanisms were studied by the organ bath technique in the thoracic aorta isolated from normotensive rats. The results indicated that the treatment of neferine (1 mg/kg and 10 mg/kg) markedly decreased the systolic blood pressure (SBP) when compared with the hypertension group (137.75 ± 10.14 mmHg and 132.23 ± 9.5 mmHg, respectively, p < 0.001), without affecting the heart rate. Moreover, neferine (10−12 − 10−4 M) exhibited concentration-dependent vasorelaxation in endothelium-intact rings (Emax values = 98.95 ± 0.66% and pD2 = 7.93 ± 0.28) and endothelium-denuded rings (Emax values = 90.61 ± 1.91% and pD2 = 6.85 ± 0.36). The effects of neferine were reduced by pre-incubation with L-NAME and 1H-[1,2,4]oxadiazolo[4,3-a] quinoxalin-1-one (ODQ) but not with pre-incubation with indomethacin and K+channel blockers. Neferine attenuated the contractions induced by phenylephrine and caffeine in a Ca2+-free solution and also inhibited in CaCl2- and phenylephrine-induced contracted rings. Our study suggests that neferine exhibited hypertensive potential, induced vasorelaxation through the endothelium nitric oxide synthase (eNOS)/nitric oxide (NO)/soluble guanylyl cyclase (sGC) pathway and involved the modulation of Ca2+ influx through Ca2+ channels and intracellular Ca2+ release from the sarcoplasmic reticulum.
Drug Leads from Endophytic Fungi: Lessons Learned via Scaled Production
Authors: Graf Tyler N. , Kao Diana , Rivera-Chávez José , Gallagher Jacklyn M. , Raja Huzefa A. , Oberlies Nicholas H. 
Published: March 2020

AbstractRecently, the isolation and elucidation of a series of polyhydroxyanthraquinones were reported from an organic extract of a solid phase culture of an endophytic fungus, Penicillium restrictum (strain G85). One of these compounds, ω-hydroxyemodin (1), showed promising quorum-sensing inhibition against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) in both in vitro and in vivo models. The initial supply of 1 was 19 mg, and this amount needed to be scaled by a factor of 30 to 50 times, in order to generate material for further in vivo studies. To do so, improvements were implemented to enhance both the fermentation of the fungal culture and the isolation of this compound, with the target of generating > 800 mg of study materials in a period of 13 wk. Valuable insights, both regarding chemistry and mycology, were gained during the targeted production of 1 on the laboratory-scale. In addition, methods were modified to make the process more environmentally friendly by judicious choice of solvents, implementing procedures for solvent recycling, and minimizing the use of halogenated solvents.
National Institutes of Health (NIH) grant awards: does past performance predict future success?
Authors: Prasad Joni M. , Shipley Michael T. , Rogers Terry B. , Puche Adam C. 
Published: March 2020

AbstractThe NIH is the major federal biomedical research funding agency within the United States, and NIH funding has become a priority in institutional decisions on faculty recruitment, salary, promotion, and tenure. The implicit assumption is that well-funded investigators will maintain their funding success; however, our analysis of NIH awardees from 2000 to 2015 suggests that regardless of how well funded an investigator is, their research portfolio exhibits “regression to the mean,” matching the typical NIH funding profile within just 10–15 years. Thus, outperformance in past funding is not a strong predictor of future outperformance in funding success. This study indicates that faculty performance should not be solely judged upon grant success but should include other institutional mission priorities such as provision of clinical care, education, and service to community/profession.
Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation
Authors: Wang Yuxin , Yang Jun , Wang Weicang , Sanidad Katherine Z. , Cinelli Maris A. , Wan Debin , Hwang Sung Hee , Kim Daeyoung , Lee Kin Sing Stephen , Xiao Hang , Hammock Bruce D. , Zhang Guodong 
Published: March 2020

SignificanceDefective intestinal barrier function and enhanced lipopolysaccharide (LPS)/bacterial translocation is a key pathogenic factor in many human diseases, including obesity. To date, the molecular mechanisms leading to intestinal barrier defects are not well understood, and there are no available therapeutic approaches to target intestinal barrier function. Here we show that soluble epoxide hydrolase (sEH) could be a novel therapeutic target of obesity-induced intestinal barrier dysfunction and LPS/bacterial translocation, and that sEH inhibitors, which have been evaluated in human clinical trials targeting other disorders, could be promising agents for prevention or treatment.
Siberian-American cognitive and cultural interface through eco-ethnic lexicon
Authors: Gural Svetlana , Kim-Maloney Alexandra , Petrova Galina 
Published: March 2020

Abstract
The focus of this paper is a possible Siberian link with the Na-Dene Languages, based on cognitive lexical
semantics. Dene-Yeniseian is a proposed language family consisting of the Yeniseian languages of Central Siberia and the Na-Dene
languages of North-Western North America (Campbell 2011; Trombetti 1923; Vajda 2010, 2011, 2018). The paper connects semantic universals, Ket and
Dene folklore, and also comparative historical linguistic research. In analyzing a group of cognates, the paper’s aim is to
discuss the cultural, cognitive and pragmatic reasons that enabled these cognates to survive for several thousand years. Our main
point is that factors such as the relative importance of linguistic signs in a language community, lingual conservatism of
semantic universals and the distinctiveness of its referents, probable frequency with which these words were used, and their
cultural symbolism in relatively similar environments significantly contributed to their survival in ethnic groups belonging to
the proposed language family. Our cross-disciplinary study helps us identify the essential place of eco-ethnic material in
interpreting cross-continental similarities and emphasizes the integrative role of culture. It will be argued that the eco-ethnic
lexicon reflected by the Dene-Yeniseian cognates reveals several thousand years of diachronic cognitive processes.
What is an indirect speech act?
Authors: Meibauer Jörg 
Published: March 2020

AbstractThe notion of an indirect speech act is at the very heart of cognitive pragmatics, yet, after nearly 50 years of orthodox (Searlean) speech act theory, it remains largely unclear how this notion can be explicated in a proper way. In recent years, two debates about indirect speech acts have stood out. First, a debate about the Searlean idea that indirect speech acts constitute a simultaneous realization of a secondary and a primary act. Second, a debate about the reasons for the use of indirect speech acts, in particular about whether this reason is to be seen in strategic advantages and/or observation of politeness demands. In these debates, the original pragmatic conception of sentence types as indicators of illocutionary force seems to have been getting lost. Here, I go back to the seemingly outdated “literal force hypothesis” (seeLevinson 1983: 263–264) and point out how it is still relevant for cognitive pragmatics.
Indirect reporting and pragmatically enriched context
Authors: Obdalova Olga A. , Minakova Ludmila Yu. , Soboleva Aleksandra V. 
Published: March 2020

AbstractThis article examines the pragmatic comprehensibility of indirect reporting. The research problem is to determine how Russian EFL learners (linguists and non-linguists) are able to turn original utterances expressing the intentions of native speakers of American English in direct speech into indirect reports to a third party. Two major issues are analyzed: adequacy of semantic content and preservation of pragmatic enrichment. The study was carried out employing the framework of Kecskes’Socio-Cognitive Approach(2008, 2010, 2014, 2017). Twelve stimulus-utterances belonging to three communicative types (statements, questions, commands/requests) were video-recorded. Qualitative and quantitative analyses revealed that the participants met with some difficulties preserving the speaker’s intention while interpreting attached pragmatic enrichment and perlocutionary effect. Both cohorts of Russian EFL learners were able to preserve the semantic content relatively efficiently, but encountered substantial difficulties inferring a complex pragmatic content.
Feasible assessment of recovery and cardiovascular health: accuracy of nocturnal HR and HRV assessed via ring PPG in comparison to medical grade ECG
Authors: Kinnunen Hannu , Rantanen Aleksi , Kenttä Tuomas , Koskimäki Heli 
Published: March 2020

Abstract

Objective: To validate the accuracy of the Oura ring in the quantification of resting heart rate (HR) and heart rate variability (HRV). Background: Wearable devices have become comfortable, lightweight, and technologically advanced for assessing health behavior. As an example, the novel Oura ring integrates daily physical activity and nocturnal cardiovascular measurements. Ring users can follow their autonomic nervous system responses to their daily behavior based on nightly changes in HR and HRV, and adjust their behavior accordingly after self-reflection. As wearable photoplethysmogram (PPG) can be disrupted by several confounding influences, it is crucial to demonstrate the accuracy of ring measurements. Approach: Nocturnal HR and HRV were assessed in 49 adults with simultaneous measurements from the Oura ring and the gold standard ECG measurement. Female and male participants with a wide age range (15–72 years) and physical activity status were included. Regression analysis between ECG and the ring outcomes was performed. Main results: Very high agreement between the ring and ECG was observed for nightly average HR and HRV (r2 = 0.996 and 0.980, respectively) with a mean bias of −0.63 bpm and −1.2 ms. High agreement was also observed across 5 min segments within individual nights in (r2 = 0.869 ± 0.098 and 0.765 ± 0.178 in HR and HRV, respectively). Significance: Present findings indicate high validity of the Oura ring in the assessment of nocturnal HR and HRV in healthy adults. The results show the utility of this miniaturised device as a lifestyle management tool in long-term settings. High quality PPG signal results prompt future studies utilizing ring PPG towards clinically relevant health outcomes.
The Effectiveness of Al-Qurun Teaching Model (ATM) Viewed from Gender Differences: The Impact on Mathematical Problem-Solving Ability
Authors: Huda Syamsul , Suherman  , Komarudin  , Syazali Muhamad , Umam Rofiqul 
Published: March 2020

Abstract
This research aimed to see the ability to solve mathematical problems between genders by applying the Al-Qurun Teaching Model. The researchers report the results of the research on the effectiveness of Al-Qurun Teaching Model on mathematical problem-solving ability viewed from gender differences. The research method used is 2 x 2 factorial design of quasi-experimental with random sampling technique. Data collection techniques used were the test method to see the results of students’ mathematical problem-solving ability. The normality test employed was Liliefors test and the homogeneity test used was the similarity of two variances. Hypothesis testing used was two-way ANAVA. The results of the study are: (1) There are differences between the Al-Qurun Teaching Model and the conventional teaching model on mathematical problem-solving ability and the use of Al-Qurun Teaching Model is more effective than the conventional teaching model, (2) There are differences in the results of mathematical problem-solving ability between female and male students and the results of mathematical problem-solving ability of female students are higher than the male students, (3) There is no interaction between learning and gender on mathematical problem-solving ability.