bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mitotic spindle disassembly in human cells relies on CRIPT-bearing hierarchical redox signals
Authors: Xu Kehan , Yang Lingling , Cheng Xiu , Liu Xiaoyan , Huang Hao , Tang Haibing , Xu Xuejiao , Wang Jingyu , Jiang Anan , Wang Chunxue , Lu Meifang , Lv Zhengmei , Shen Lin , Song Feifei , Zhou Haoqian , Zhou Haisheng , Liu Xinhua , Shi Weibing , Zhou Jinghua , Li Xuejun , Li Hong , Cai Chunlin 
Published: December 2019

AbstractSwift and complete spindle disassembly is essential for cell survival, yet how it happens is largely unknown. Here we used real-time live-cell microscopy and biochemical assays to show that a cysteine-rich protein CRIPT dictates the spindle disassembly in a redox-dependent manner in human cells. This previously reported cytoplasmic protein was found to have a confined nuclear localization during interphase but was distributed to spindles and underwent redox modifications to form disulfides within CXXC pairs during mitosis. Then, it interacts with and transfers redox response to tubulin subunits to induce microtubule depolymerization. The mutants with any of cysteine substitution completely block the spindle disassembly generating two cell populations with long-lasting metaphase spindles or spindle remnants. The live cell recordings of a disease-relevant mutant (CRIPTC3Y) revealed that microtubule depolymerization at spindle ends during anaphase and the entire spindle dissolution during telophase may share a common CRIPT-bearing redox-controlled mechanism.
Evolutionary and Comparative analysis of bacterial Non-Homologous End Joining Repair
Authors: Sharda Mohak , Badrinarayanan Anjana , Seshasayee Aswin Sai Narain 
Published: December 2019

AbstractDNA double-strand breaks (DSBs) are a threat to genome stability. In all domains of life, DSBs are faithfully fixed via homologous recombination. Recombination requires the presence of an uncut copy of duplex DNA that is used as a template for repair. Alternatively, in the absence of a template, cells utilize error-prone Non-homologous end joining (NHEJ). Although ubiquitously found in eukaryotes, NHEJ is not universally present in bacteria. It is unclear as to why many prokaryotes lack this pathway. To understand what could have led to the current distribution of bacterial NHEJ, we carried out comparative genomics and phylogenetic analysis across ~6000 genomes. Our results show that this pathway is sporadically distributed across the phylogeny. Ancestral reconstruction further suggests that NHEJ was absent in the eubacterial ancestor, and can be acquired via specific routes. Integrating NHEJ occurrence data for archaea, we also find evidence for extensive horizontal exchange of NHEJ genes between the two kingdoms as well as across bacterial clades. The pattern of occurrence in bacteria is consistent with correlated evolution of NHEJ with key genome characteristics of genome size and growth rates; NHEJ presence is associated with large genome sizes and/or slow growth rates, with the former being the dominant correlate. Given the central role these traits play in determining the ability to carry out recombination, it is possible that the evolutionary history of bacterial NHEJ may have been shaped by requirement for efficient DSB repair.
Crystal structure, thermodynamic properties and detonation characterization of bis(5-amino-1,2,4-triazol-3-yl)methane
Authors: Li Hongya , Yan Biao , Ma Haixia , Sun Zhiyong , Ma Yajun , Zhang Zhifang 
Published: December 2019

Bis(5-amino-1,2,4-triazol-3-yl)methane (BATZM, C5H8N8) was synthesized and its crystal structure characterized by single-crystal X-ray diffraction; it belongs to the space group Fdd2 (orthorhombic) with Z = 8. The structure of BATZM can be described as a V-shaped molecule with reasonable chemical geometry and no disorder. The specific molar heat capacity (Cp,m
) of BATZM was determined using the continuous Cp
mode of a microcalorimeter and theoretical calculations, and the Cp,m
value is 211.19 J K−1 mol−1 at 298.15 K. The relative deviations between the theoretical and experimental values of Cp,m
, HT
– H
298.15K and ST
– S
298.15K of BATZM are almost equivalent at each temperature. The detonation velocity (D) and detonation pressure (P) of BATZM were estimated using the nitrogen equivalent equation according to the experimental density; BATZM has a higher detonation velocity (7954.87 ± 3.29 m s−1) and detonation pressure (25.72 ± 0.03 GPa) than TNT.
Effect of Al on the microstructure, corrosion behavior and mechanical properties of Mg-4Li
Authors: Zhang Cheng , Wu Liang , Zhao Zilong , Huang Guangsheng , Jiang Bin , Atrens A. , Pan Fusheng 
Published: December 2019

Purpose
This paper aims to investigate microstructure, corrosion behavior and mechanical properties of Mg-4Li and Mg-4Li-3Al.

Design/methodology/approach
The microstructure was characterized by using scanning electron microscopy and electron backscatter diffraction. The corrosion behaviors were measured by hydrogen evolution and potentiodynamic polarization tests. The mechanical properties were evaluated by tensile tests.

Findings
The addition of Al results in the precipitation of some Mg-Al phase and Al3Li phase particles, and the formation of some fine recrystallized grains.

Originality/value
Mg-4Li-3Al showed a higher corrosion rate than that of Mg-4Li, attributed to the precipitate particles in Mg-4Li-3Al causing microgalvanic corrosion and the change of grain orientation. The addition of 3 Wt. per cent Al increased the tensile strength by solid solution strengthening, precipitation strengthening, refinement strengthening and texture strengthening, whilst the elongation decreased by almost half.
A systematic review of the antecedents of knowledge transfer: an actant-object view
Authors: Shahbaznezhad Hamidreza , Rashidirad Mona , Vaghefi Isaac 
Published: December 2019

Purpose
While numerous studies have studied knowledge transfer (KT) and endeavored to address factors influencing KT, little effort has been made to integrate the findings of prior studies. This paper aims to classify the literature on KT through a detailed exploration of different perspectives of KT inter and intra organizations.

Design/methodology/approach
Using actor–network theory (ANT) as the baseline, we conducted a systematic review of KT research to summarize prior KT studies and classify the influential factors on KT. The review covered 115 empirical articles published between 1987 and 2017.

Findings
Drawing on the review and ANT guidelines, the authors proposed a conceptual model to categorize KT constitutes into objects including those related to (1) knowledge, (2) knowledge exchange and (3) technology, as well as actants including those related to (4) organization, (5) team/business unit and (6) knowledge sender/receiver.

Research limitations/implications
Adopting a holistic synthesized approach based on ANT, this research puts forward a valid theoretical foundation on further understanding of KT and its antecedents. Indeed, this paper investigates KT inter and intra organizations to recognize and locate the key antecedents of KT, which is of substantial applicability in today’s knowledge-driven economy.

Practical implications
The findings advance managers and practitioners’ understanding of the important role of actants and objects and their interplay in KT practices.

Originality/value
While most studies on KT have a narrow focus, this research contributes to holistic understanding of motivational, behavioral, technological and organizational issues related to KT. It also offers a thorough and context-free literature review on KT, which synthesizes the findings of prior studies on KT.
Hope Home: early childhood education for social change
Authors: Benetti Sara , Zúñiga Roy 
Published: December 2019

Learning outcomes
This case is to familiarize students with the peculiarities of social enterprises (SEs). They would be able to recognize that SEs are hybrid organizations that merge a social purpose with the managerial logics of business ventures. Because of this dual nature, social entrepreneurs need to balance their social aim and the financial viability of the project when analyzing different ways to grow the business, as well as understand and address internal tensions that arise because they have to deal with diverse stakeholders. At the end of the analysis, students would have clear that social and commercial ventures respond to different logics, and therefore, require different managerial models.

Case overview/synopsis
Andrea Meoño was the founder of Hope Home, a center for early childhood education in San José, Costa Rica. The goal of the center was to provide education and daily care to children of disadvantaged families, especially single mothers for whom it was a real challenge to maintain a permanent job to sustain their children, and at the same time, provide them with adequate care and attention. After five years of operating the center, Andrea had to figure out the best way to grow her business, ensuring financial sustainability while keeping true to her original purpose of helping vulnerable mothers by providing their children with excellent educational opportunities.

Complexity academic level
Master’s and Master of Business Administration students taking a course on social entrepreneurship.

Supplementary materials
Teaching Notes are available for educators only. Please contact your library to gain login details or email support@emeraldinsight.com to request teaching notes.

Subject code
CSS 3: Entrepreneurship
The good, the bad, and the ugly: organizational effectivity in human resources processes
Authors: Gaytán-Jiménez María de Guadalupe GG , López-Hernández Carlos Eduardo , Cordero-Estefan Jaqueline 
Published: December 2019

Learning outcomes
Students are expected to achieve identify the prerequisites and basic to an institutionalization process; prioritize strategic human resources processes as a basis for the growth of the company; analyze the importance of the stages in human resources management; define the areas of opportunity and their respective action plans; and propose the leadership skills that a leader requires.

Case overview/synopsis
Tramuntana® is a travel agency that stands out for being a prime service, which is promoted by its own customers. Its founder wishes to institutionalize his company. The main problem in which they face to grow and consolidate is to maintain their human resources, and in which they cannot be retained, and therefore, do not have a solid structure.

Complexity academic level
Undergraduate and Graduate School of Business and executive education.

Supplementary materials
Teaching Notes are available for educators only. Please contact your library to gain login details or email support@emeraldinsight.com to request teaching notes.

Subject code
CSS 1: Accounting and Finance.
Modeling corporate financial distress using financial and non-financial variables
Authors: Balasubramanian Senthil Arasu , G.S. Radhakrishna , P. Sridevi , Natarajan Thamaraiselvan 
Published: December 2019

Purpose
This paper aims to develop a corporate financial distress model for Indian listed companies using financial and non-financial parameters by using a conditional logit regression technique.

Design/methodology/approach
This study used a sample of 96 companies, of which 48 were declared sick between 2014 and 2016. The sample was divided into a training sample and a testing sample. The variables for the study included nine financial variables and four non-financial variables. The models were developed using financial variables alone as well as combining financial and non-financial variables. The performance of the test sample was measured with confusion matrix, sensitivity, specificity, precision, F-measure, Types 1 and 2 error.

Findings
The results show that models with financial variables had a prediction accuracy of 85.19 and 86.11 per cent, whereas models with a combination of financial and non-financial variables predict with comparatively better accuracy of 89.81 and 91.67 per cent. Net asset value, long-term debt–equity ratio, return on investment, retention ratio, age, promoters holdings pledged and institutional holdings are the critical financial and non-financial predictors of financial distress.

Originality/value
This study contributes to the financial distress prediction literature in different ways. First, there have been, until now, few studies in the area of financial distress prediction in the Indian context. Second, business failure studies in the past have used only financial variables. The authors have combined financial and non-financial variables in their model to increase predictive ability. Thirdly, in most earlier studies, variable institutional holdings were found to affect financial distress negatively. In contrast, the authors found this parameter to be positively significant to the financial distress of the company. Finally, there have hitherto been few studies that have used promoter holdings pledged (PHP) or pledge ratio. The authors found this variable to influence business failure positively.
Mechanical research on aerostatic guideways in consideration of fluid-structure interaction
Authors: Yan Ruzhong , Wang Liaoyuan , Wang Shengze 
Published: December 2019

Purpose
The purpose of this paper is to study the mechanical properties of aerostatic guideway taking the structural deformation into account, and further improve the calculation method of guideway.

Design/methodology/approach
A theoretical model of fluid-structure interaction for the numerical simulation was established and mechanical properties of the aerostatic guideway with porous restrictors were solved based on computational fluid dynamics. The deformation law of the guideway with different materials and gas-film thicknesses was revealed, and its static and dynamic characteristic curves were obtained.

Findings
The results indicate that ceramics as the material of guideways exhibit good applicability due to the small deformation, the quick dynamic response and the relatively light weight. The rational initial gas-film of guideway is recommended.

Originality/value
The present work can provide ideas for the design and optimization of aerostatic guideways.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-07-2019-0288
Testing fisher effect for the USA: application of nonlinear ARDL model
Authors: Ongan Serdar , Gocer Ismet 
Published: December 2019

PurposeThis paper aims to investigate the presence of the Fisher effect for the USA from a new methodological perspective differing it from all previous studies using the common linear representation of the Fisher equation.Design/methodology/approachThe nonlinear ARDL model, recently developed by Shinet al.(2014), is applied for the 10-year US Government bond rates over the period of 1985M1-2017M10.FindingsThe empirical findings indicate that the US Federal Reserve (FED) is a more predominant arbiter in the determination of interest rates during periods of declining inflation rates than periods of rising inflation rates. This finding may allow the FED to apply more proactive and prudent monetary policy. Additionally, this study newly describes and introduces a different version of the partial Fisher effect and extends the Fisher equation to some degree in terms of the partial Fisher effect.Originality/valueTo the best the authors’ knowledge, this method is applied for the first time in testing the Fisher effect for the USA.
Resilient agility in volatile economies: institutional and organizational antecedents
Authors: Gölgeci Ismail , Arslan Ahmad , Dikova Desislava , Gligor David M. 
Published: December 2019

PurposeThe purpose of this paper is to scrutinize the interplay between resilience and agility in explicating the concept of resilient agility and discuss institutional and organizational antecedents of resilient agility in volatile economies.Design/methodology/approachThe authors develop a conceptual framework that offers an original account of underlying means of ambidextrous capabilities for organizational change and behaviors in volatile economies and how firms stay both resilient and agile in such contexts.FindingsThe authors suggest that resilient agility, an ambidextrous capability of sensing and acting on environmental changes nimbly while withstanding unfavorable disruptions, can explain entrepreneurial firms’ survival and prosperity. The authors then address institutional (instability and estrangement) and organizational (entrepreneurial orientation (EO) and bricolage) antecedents of resilient agility in volatile economies.Originality/valueThe authors highlight that unfavorable conditions in volatile economies might have bright sides for firms that can leverage them as entrepreneurial opportunities and propose that firms can achieve increased resilient agility when high levels of institutional instability and estrangement are matched with high levels of EO and bricolage.
Do institutional investors have homogeneous influence on corporate social responsibility? Evidence from investor investment horizon
Authors: Meng Yun , Wang Xiaoqiong 
Published: December 2019

Purpose
The purpose of this paper is to investigate the relation between the investment horizon of institutional investors and corporate social responsibility (CSR).

Design/methodology/approach
Utilizing unique datasets on CSR and the investor horizon measures (Gaspar et al., 2005), the authors categorize institutional investors into long-term and short-term investors. This method captures the heterogeneity of investors.

Findings
The authors show that long-term institutional investors promote CSR engagement, while short-term investors discourage it. The authors further document that shareholders’ ownership horizon has implications on corporate decisions in the CSR framework. The presence of long (short)-term institutional investors is positively (negatively) associated with dividend payout, discourages (encourages) managerial misbehaviors and enhances (reduces) firm valuation, only for firms with high CSR performance.

Research limitations/implications
Different from previous studies that treat institutional investors homogeneously, this paper provides empirical support that investors are indeed different in influencing CSR.

Originality/value
Few prior studies address the question of whether active engagement by institutional shareholders on CSR issues differs by the types of institutional ownership. The study attempts to fill this gap by examining the effects of institutions’ investment horizon, one of the major ways to classify institutional shareholders, on the CSR performance of firms.
Jamaica’s development of women entrepreneurship: challenges and opportunities
Authors: Saner Raymond , Yiu Lichia 
Published: December 2019

PurposeThe purpose of this paper is to assess how far Jamaica has come regarding women economic empowerment, female entrepreneurship and its development policies in favour of women entrepreneurship development.Design/methodology/approachThis exploratory study employs a mixed method approach to achieve its research objectives, consisting of literature review and corroboration with existing database and indices. Key insights of research on female entrepreneurship are used to reflect on published data to assess progress of female entrepreneurship development in Jamaica. The 2017 editions of the Global Entrepreneurship Monitor and Gender Entrepreneurship and Development Index were examined to gain a better understanding of how the Jamaican business environment has progressed or regressed over time and how the economic development and business environment impact female participation in Jamaica’s labour force and entrepreneurial initiatives.FindingsThe economic conditions in Jamaica and the role of females as domestic caregiver have made it difficult for women to enter the labour force even though Jamaican women are relatively better educated than men. Women remain at a disadvantage in the labour force. Jamaica’s legislation and budget allocations in favour of female entrepreneurship are analysed to identify where and how Jamaica is investing its efforts to improve women’s participation in the labour force. The authors conclude with suggestions on how the Jamaican government could facilitate further women entrepreneurship development to reach a more gender balanced inclusive socio-economic development.Originality/valueWhile global policy has been promoting women empowerment through entrepreneurial development, little is known on the actual outcome of such human capital investment strategy and the critical vectors that contribute to such outcome. This scarcity of knowledge is also applicable to Jamaica. This paper attempts to contribute to women entrepreneurship research by reaching beyond the output-oriented perspective of various skill development programmes and attempts to link policy choice with overall macro results of entrepreneurship development in general and women entrepreneurship development in specific. The study thus provides a rare glimpse of the entrepreneurship ecosystem in Jamaica.
Urban resilience and sustainable development policies
Authors: da Silva Cristiane Aparecida , dos Santos Edicreia Andrade , Maier Stefania Maria , da Rosa Fabricia Silva 
Published: December 2019

Purpose
The purpose of this paper is to analyze the urban resilience capacity and its relations with the economic, social and environmental well-being in smart cities in the state of São Paulo (SP), particularly after the 2008 financial crisis.

Design/methodology/approach
Concerning its objectives, this study is characterized as descriptive. From the point of view of technical procedures, the research is bibliographic, and regarding data collection, it is documental. The approach of this research is quantitative, since it uses the statistical method. The sample was made up by 62 smart cities located in SP. The analysis comprised the period from 2010 to 2015.

Findings
The urban resilience pillars influence the economic well-being represented by the gross national product, in 58.8 percent, social well-being represented by the life expectancy of the residents of the smart cities, in 71.7 percent, and in environmental well-being indicated by CO2 emissions, in 21.5 percent.

Research limitations/implications
They are related to the researchers’ decision about the methodological design.

Practical implications
This study was limited to smart cities in SP listed in the RBCIH (Brazilian Network of Human Smart Cities), and may be extended to other cities in other Brazilian states.

Social implications
How resilience dimensions related to economic, social and environmental well-being such as poverty, food security, health, well-being, education quality, climate changes, and the like, were measured, which can be investigated in future research studies.

Originality/value
Despite its growing popularity worldwide, the urban resilience pillars and their relationship with human well-being in smart cities in the national context are little investigated, making this research original.