bluuebunny/crossref_metadata_2025_split huggingface dataset:
Herpes zoster: Epidemiological Features of the Incidence in 2019
Authors: Kaira A. N. , Lavrov V. F. 
Published: November 2020

The urgency of the problem of herpes zoster (shingles) consists in its wide distribution in the world, high incidence rates in a significant part of the subjects of the Russian Federation, as well as the severity of complications caused by this infection.The aimof the study was to analyze the epidemiological characteristics of the incidence of herpes zoster in Russia.Materials and methods. Epidemiological analysis of the incidence of herpes zoster in the Russian Federation was conducted using official statistics.Results and discussion. In 2019, in a number of administrative divisions of the Russian Federation, there was a poor epidemic situation associated with the incidence of herpes zoster. In some regions, the incidence rates were significantly higher than the national average, and the elderly were the most vulnerable. It turned out that the existing methods of prevention of herpes zoster, aimed mainly at promoting a healthy lifestyle and hygienic education of the population, do not bring the desired results, and the incidence of herpes zoster (secondary VZV infection) remains high.Conclusions. The analysis of the incidence of herpes zoster during the reporting period demonstrates the need for constant statistical accounting of the spread of this infection on the territory of Russia, actualizes the conduct of full-fledged epidemiological surveillance and the organization of a system of preventive measures, which should be based on the development, production and practical application of a domestic vaccine against herpes zoster.
PENGARUH PENAMBAHAN TEPUNG KACANG MERAH TERHADAP SIFAT KIMIA DAN HEDONIK BERAS ANALOG BERBAHAN DASAR UMBI GANYONG (CannaedulisKer.)
Authors: Salsabila Salma , Hintono Antonius , Setiani Bhakti Etza 
Published: November 2020

Analog rice is artificial rice product made from non rice raw material which contain nutrients and looks like padi rice. This research using raw material such as umbi ganyong as source of carbohydrates and red bean to improve the nutritional value and appearance of analog rice. The purpose of this research was to study the concentration effect offered bean flour added into on rice analog made from umbi ganyong (ganyong root) toward water content, raw fiber, protein, and hedonic. The treatments applied were T0 for 0% concentration, T1 for 5% concentration, T2 for 10% concentration, and T3 for 15% concentration. The observed variables were water content, protein, crude fiber, and preference level. The result of the study showed that the addition of red bean flour with various concentrations reveals the difference(p<0,05) in rising water content, crude fiber, protein, and improving taste, texture, and rice analog fluffiness. The outcome of the research point out that the recommendation of red bean flour added into analog rice was at 15% which were resulting in water content 7,76±0,152%, crude fiber of 3,01±0,68%, and protein 7,41±0,038%,
Penggunaan Alat Mewarnai Gambar Bagi Pemula Menggunakan Metode AHP dan Weight Product
Authors: Syabaniah Rifa Nurafifah , Wibowo Agung , Marsusanti Eva 
Published: November 2020

The process of selecting a drawing coloring tool in one of the Cianjur city painting studios takes a long time, because the child must first try each type of drawing coloring tool. based on this problem discussed about the selection of coloring tools for beginners by using the Analytic Hierarchy Process (AHP) and Product Weight (WP) methods. AHP test results obtained five criteria, namely comfort, convenience, safety, color quality and product quality of the ten recommended criteria based on observations and interviews. The five criteria are used as criteria for determining the selection of drawing tools for crayons, colored pencils, watercolors, markers, and oil pastels. the final result of the calculation of the Analytical Hierarchy Process (AHP) method shows that crayons are the most important alternative with a weight value of 0.20. while the test results of the Weighted Product (WP) method conclude that the brand code V4 is the crayon product brand chosen because the brand code V4 has the highest alternative value of the other ten products namely V4 = 0.118.
Pemanfaatan Energi Surya untuk Penerangan Jalan & Fasilitas Umum di Desa Sukarame Kab. Lebak Banten
Authors: Putri Tri Wahyu Oktaviana , Senen Adri , Simamora Yoakim 
Published: November 2020

Jalan sebagai salah satu sarana umum yang vital dalam menghubungkan antar daerah satu ke daerah yang lainnya. Oleh karena itu, keberadaaan penerangan jalan umum (PJU) adalah hal yang sangat penting demi kelancaran aktivitas warga di malam hari. Tetapi, tidak semua ruas jalan telah terpasang PJU. Misalnya ruas jalan desa di Desa Sukarame, Kec. Sajira, Kab. Lebak, Banten. Desa ini merupakan desa yang dialiri arus listrik tetapi pasokan listrik untuk PJU masih sangat terbatas. Oleh karena itu diperlukan pemasangan PJU berupa lampu tenaga surya sebagai alternatif efektif bagi penerangan jalan dan fasilitas umum. Lampu tenaga surya dipilih mengingat lampu tersebut tidak memerlukan pasokan listrik dari rumah warga dan keadaan geografis desa yang sangat potensial untuk memanfaatkan energi surya. Lampu tenaga surya dipasang pada 3 titik strategis yaitu di jalan kampung depan TK, jalan kampung depan lapangan, dan teras mushola. Selain pemasangan lampu untuk penerangan umum, analisis ekonomi juga dilakukan pada kegiatan ini dengan cara membandingkan total biaya yang diperlukan PJU lampu surya dengan total biaya PJU lampu pijar. Walaupun harga PJU tenaga surya lebih mahal, tetapi untuk penggunaan jangka panjang, PJU tenaga surya jauh lebih ekonomis dibandingkan PJU lampu pijar, dengan selisih biayanya sebesar Rp 636.582,80 pertiang dalam jangka waktu pemakaian 3 tahun.
Sosialisasi Keamanan Listrik Rumah Tangga di RW 08 Ciomas Permai, Bogor
Authors: Hasanah Aas Wasri , Pujotomo Isworo , Qosim Muchamad Nur , Koerniawan Tony , Haryati Rinna , Widyastuti Christine , Handayani Oktaria 
Published: November 2020

Abstrak
Listrik merupakan bentuk energi yang paling cocok dan tepat bagi kehidupan manusia modern seperti dewasa ini, dimana energi listrik mempunyai fungsi yang dapat memberikan suatu kebutuhan atau pelayanan daya listrik yang diperoleh oleh konsumen, dengan listrik kehidupan manusia menjadi sangat menyenangkan. Televisi, lampu penerangan, lampu lalu lintas, semua menggunakan listrik. Jadi, listrik dapat dikatakan sebagai suatu bentuk hasil teknologi yang sangat vital dalam kehidupan manusia. Dengan kegiatan ini, maka diharapkan masyarakat umum bisa dan paham tentang instalasi listrik yang aman dan penanganan, penanggulangan dari bahaya listrik yang tidak sesuai dengan standarisasi PLN. Sehingga listrik tidak serta merta menjadi kambing hitam setiap saat ada kejadian kebakaran di lingkungan masyarakat, dan sistem tegangan yang digunakan di Indonesia adalah: fasa-tunggal 220 V, dan fasa-tiga 220/380 V dengan frekuensi 50 Hz. Sistem tegangan ini sangat mempengaruhi dan berbahaya bagi keselamatan manusia.

Kata kunci : kabel, tegangan, arus, instalasi, konsleting
Desain Instalasi Listrik Bangunan Bertingkat (Studi Kasus: Pesantren Khoiru Ummah Sumedang)
Authors: Hajar Ibnu , Damiri Dhami Johar , Yuliasyah Yuliasyah , Jumiati Jumiati , Lesmana M. Syair Pandu , Romadhoni Muhammad Iqbal 
Published: November 2020

The electrical installation is a circuit of electrical equipment which is interconnected with one another and it is within the scope of the electrical power system. This article is to present the result of social community service (PkM) activity at Boarding School of STP SMP/SMA KU Sumedang, that shows an electrical installation design of multi-storey building. In construction of multi-storey building of this boarding school, they do not have an electrical installation design. So, the design in this article is to provide design drawings of the electrical installation, so it could be guidance of setting up of electrical installation for the new boarding school building. So that, they got the electrical installation safely for human and the equipment, as well reliable and comfort during using electricity. The design drawings that resulted from the social community service are drawings of front look, beside look, wiring, and single line diagram (SLD). Also, resulted total power calculation, protection, and capacity (rating) of MCB, and calculated cable rating (KHA), choosing type and cross-sectional area of cables that will be used in electrical installation design for the boarding school building.
Down-Regulated FOXO1 in Refractory/Relapse Childhood B-Cell Acute Lymphoblastic Leukemia
Authors: Zheng Qingqing , Jiang Chuang , Liu Haiyan , Hao Wenge , Wang Pengfei , Huang Haiying , Li Ziping , Qian Jiabi , Qian Maoxiang , Zhang Hui 
Published: November 2020

Background: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall prevalence of 4/100,000, accounting for 25–30% of all childhood cancers. With advances in childhood ALL treatment, the cure rate for childhood ALL has exceeded 80% in most countries. However, refractory/relapsed ALL remains a leading cause of treatment failure and subsequent death. Forkhead box O1 (FOXO1) belongs to the forkhead family of transcription factors, but its role in B-cell ALL (B-ALL) has not been determined yet.Procedures: RNA sequencing was applied to an ALL case with induction failure (IF) to identify the possible genetic events. A cytokine-dependent growth assay in Ba/F3 cells was used to test the leukemic transformation capacity of MEIS1–FOXO1. The propidium iodide (PI) staining method was used to evaluate the effect of MEIS1–FOXO1 on cycle distribution. FOXO1 transactivity was examined using a luciferase reporter assay. FOXO1 mRNA expression levels were examined using real-time quantitative PCR among 40 children with B-ALL treated with the CCCG-ALL-2015 protocol. Association analysis was performed to test the correlation of FOXO1 transcription with childhood B-ALL prognosis and relapse in a series of GEO datasets. An MTT assay was performed to test the drug sensitivity.Results: In this ALL case with IF, we identified a novel MEIS1–FOXO1 fusion gene. The transactivity of MEIS1–FOXO1 was significantly lower than that of wild-type FOXO1. MEIS1–FOXO1 potentiated leukemia transformation and promoted Ba/F3 cell cycle S-phase entry. Low FOXO1 transcription levels were found to be strongly associated with unfavorable ALL subtype, minimal residual disease (MRD) positivity, and relapse. Lower FOXO1 expression was associated with prednisone and cyclophosphamide resistance.Conclusions: Low FOXO1 transcription was associated with high-risk stratification and relapse in children with B-ALL, probably due to multi-drug resistance.
Identifying Antibiotic Prescribing Patterns Through Multi-Level Latent Profile Analyses: A Cross-Sectional Survey of Primary Care Physicians
Authors: Wang Dan , Liu Chaojie , Zhang Xinping , Liu Chenxi 
Published: November 2020

Background: Overuse of antibiotics significantly fuels the development of Antimicrobial resistance, which threating the global population health. Great variations existed in antibiotic prescribing practices among physicians, indicating improvement potential for rational use of antibiotics. This study aims to identify antibiotic prescribing patterns of primary care physicians and potential determinants.Methods: A cross-sectional survey was conducted on 551 physicians from 67 primary care facilities in Hubei selected through random cluster sampling, tapping into their knowledge, attitudes and prescribing practices toward antibiotics. Prescriptions (n = 501,072) made by the participants from 1 January to March 31, 2018 were extracted from the medical records system. Seven indicators were calculated for each prescriber: average number of medicines per prescription, average number of antibiotics per prescription, percentage of prescriptions containing antibiotics, percentage of antibiotic prescriptions containing broad-spectrum antibiotics, percentage of antibiotic prescriptions containing parenteral administered antibiotics, percentage of antibiotic prescriptions containing restricted antibiotics, and percentage of antibiotic prescriptions containing antibiotics included in the WHO “Watch and Reserve” list. Two-level latent profile analyses were performed to identify the antibiotic prescribing patterns of physicians based on those indicators. Multi-nominal logistic regression models were established to identify determinants with the antibiotic prescribing patterns.Results: On average, each primary care physician issued 909 (ranging from 100 to 11,941 with a median of 474) prescriptions over the study period. The mean percentage of prescriptions containing antibiotics issued by the physicians reached 52.19% (SD = 17.20%). Of those antibiotic prescriptions, an average of 82.29% (SD = 15.83%) contained broad-spectrum antibiotics; 71.92% (SD = 21.42%) contained parenteral administered antibiotics; 23.52% (SD = 19.12%) contained antibiotics restricted by the regional government; and 67.74% (SD = 20.98%) contained antibiotics listed in the WHO “Watch and Reserve” list. About 28.49% of the prescribers were identified as low antibiotic users, compared with 51.18% medium users and 20.33% high users. Higher use of antibiotics was associated with insufficient knowledge, indifference to changes, complacency with satisfied patients, low household income and rural location of the prescribers.Conclusion: Great variation in antibiotic prescribing patterns exists among primary care physicians in Hubei of China. High use of antibiotics is not only associated with knowledge shortfalls but also low socioeconomic status of prescribers.
The assessment of knowledge, attitude and practice towards tuberculosis infection control among health professionals in Nekemte referral hospital, Nekemte, Oromia, West Ethiopia: cross sectional facility based study
Authors: Golja Eba Abdisa 
Published: November 2020

Infection control remains a key challenge for Tuberculosis control program with an increased risk of Tuberculosis transmission among health care workers. Poor knowledge, poor practice and poor attitude among health care workers and inadequate infection control practices may lead to the increased risk of nosocomial Tuberculosis transmission. People living in the same household, or who otherwise are in frequent contact with an infected patient have the greatest risk of being exposed to the bacilli.
This study was aimed to assess knowledge, attitude and practice of health professionals towards tuberculosis infection control in Nekemte referral hospital, Nekemte, west Ethiopia, 2018.
Institutional based cross sectional study design was conducted from December 2017 to January 2018 among 223 health professionals in Nekemte referral hospital. Data was collected by using self-administered structured questionnaires which has subdivided components, and finally the analysis was done by double entry of SPSS version 21.
Two hundred study participants responded to our current study with response rate of 200(89.6%). In this study, majority of respondents, 54% were females and 55% of them are first degree holders. From 200 participants, 14 (7%) had poor knowledge. Majority, 157(78.5%) of health care workers, had positive attitudes towards Tuberculosis infection control. Sixty (30%) of participants had poor practice.
This study found that significantly high proportion of health workers had good knowledge and practice towards tuberculosis infection control. More than half of health workers wrongly believed that surgical mask can protect health workers from inhaling mycobacterium containing aerosols.
Integración de la educación digital y los aportes de las TIC, JCLIC a los procesos de enseñanza y aprendizaje en la escuela
Authors: Malpica Capacho Alonso 
Published: November 2020

El propósito del artículo es hacer una reflexión desde la integración de la educación digital y los aportes de las TIC, para identificar los aspectos relevantes de la contribución del software educativo JCLIC en los procesos de innovación escolar. En el texto se argumenta sobre la importancia que tienen los docentes para apropiarse e implementar a su práctica pedagógica habilidades, competencias digitales, etilos de aprendizaje y aplicaciones para entornos virtuales que ofrece la web; así mismo, se explica el papel del docente, en el uso de las herramientas tecnológicas, la interacción digital y los procesos de comunicación en la innovación a través del software JCLIC en el contexto escolar.
Frequency of Thyrotoxicosis in Patient with One Sided Exophthalmos
Authors: Zafar Tahreem , Perveen Shumaila , Khan Nisar , Khan Salman , Ahmed Tahseen 
Published: November 2020

Background: Thyroid associated Opthalmo-pathy is a condition of lid retraction causing a staring appearance. This occurs in any form of thyrotoxicosis as a result of sympathetic overactivity.Exophthalmos is the forward protrusion of eye ball beyond the orbital rim.
Material & Methods: This case series was observed in medical department Mufti Mehmood Teaching Hospital DIKhan, Pakistan over a period of eight months from February 2018 to September 2018. Detailed history with reference of duration of illness, mode of onset, progression and associated symptoms like fever, pain, diplopia and loss of vision was taken. Complete examination of orbit, eyelid, anterior and posterior segment was done. Routine Investigations along with special diagnostic tests like TFTs and MRI were performed to aid etiological diagnosis.
Results: A total 47 patients were observed during this study period. Out of these 20 (21.27%) were male and 27 (57.44%) were female with male to female ratio 1:1.35 with mean age of 32 years. Out of 47 patients30 (63.82%) patients were having thyrotoxicosis as a cause of exophthalmos, 10(21.27%) were having retrobulbartumour, 5(10.63%) patients were with cavernous sinus thrombosis and 2(4.25%) patients were having idiopathic cause of exophthalmos.
Conclusion: Thyrotoxicosis is the common cause of one sided exophthalmos and should be considered in all patients with one sided exophthalmos.
A Perturbative Treatment of the Retrograde Co-orbital Motion
Authors: Sidorenko Vladislav V. 
Published: November 2020

Abstract
An important area of research in celestial mechanics is the analysis of dynamics in mean-motion resonances (MMR). In this paper, we consider a retrograde MMR 1:1 corresponding to a co-orbital motion, in which the asteroid and the planet revolve around the Sun in opposite directions. The motivation was provided by the recent discovery of real celestial bodies moving in such resonances with giant planets (the most famous example being 514107 Ka‘epaoka‘awela, a retrograde co-orbital asteroid of Jupiter). Our study is conducted in the context of a spatial restricted circular three-body problem. Applying double numerical averaging, we construct the equations describing the secular evolution of the asteroid's orbit and generate phase portraits in an e − ω space. In some cases, the averaging procedure is complicated by the coexistence of several modes of resonant motion. It leads to different scenarios of the long-term behavior and, consequently, to the splitting of the phase portrait into several sheets.
A Non-equipartition Shock Wave Traveling in a Dense Circumstellar Environment around SN 2020oi
Authors: Horesh Assaf , Sfaradi Itai , Ergon Mattias , Barbarino Cristina , Sollerman Jesper , Moldon Javier , Dobie Dougal , Schulze Steve , Pérez-Torres Miguel , Williams David R. A. , Fremling Christoffer , Gal-Yam Avishay , Kulkarni Shrinivas R. , O’Brien Andrew , Lundqvist Peter , Murphy Tara , Fender Rob , Anand Shreya , Belicki Justin , Bellm Eric C. , Coughlin Michael W. , De Kishalay , Golkhou V. Zach , Graham Matthew J. , Green Dave A. , Hankins Matt , Kasliwal Mansi , Kupfer Thomas , Laher Russ R. , Masci Frank J. , Miller A. A. , Neill James D. , Ofek Eran O. , Perrott Yvette , Porter Michael , Reiley Daniel J. , Rigault Mickael , Rodriguez Hector , Rusholme Ben , Shupe David L. , Titterington David 
Published: November 2020

Abstract
We report the discovery and panchromatic follow-up observations of the young Type Ic supernova (SN Ic) SN 2020oi in M100, a grand-design spiral galaxy at a mere distance of 14 Mpc. We followed up with observations at radio, X-ray, and optical wavelengths from only a few days to several months after explosion. The optical behavior of the supernova is similar to those of other normal SNe Ic. The event was not detected in the X-ray band but our radio observations revealed a bright mJy source (

L

ν

≈
1.2
×

10

27

erg

s

−
1

Hz

−
1

). Given the relatively small number of stripped envelope SNe for which radio emission is detectable, we used this opportunity to perform a detailed analysis of the comprehensive radio data set we obtained. The radio-emitting electrons initially experience a phase of inverse Compton cooling, which leads to steepening of the spectral index of the radio emission. Our analysis of the cooling frequency points to a large deviation from equipartition at the level of ϵ

e
/ϵ

B
≳ 200, similar to a few other cases of stripped envelope SNe. Our modeling of the radio data suggests that the shock wave driven by the SN ejecta into the circumstellar matter (CSM) is moving at

∼
3
×

10

4

km

s

−
1

. Assuming a constant mass loss from the stellar progenitor, we find that the mass-loss rate is

M

̇

≈
1.4
×

10

−
4

M

⊙

yr

−
1

for an assumed wind velocity of

1000

km

s

−
1

. The temporal evolution of the radio emission suggests a radial CSM density structure steeper than the standard r
−2.
L’acte de Tenir conseil
Authors: Lhotellier Alexandre 
Published: November 2020

Le conseil, pratique traditionnelle très forte, s’est souvent banalisé en « donner des conseils », le contraire de « tenir conseil » : délibérer pour agir. Nous avons aussi oublié le sens politique fondamental du terme, comme dans conseil municipal, gouvernemental, etc. Le conseil est à la base même de la démocratie. Mais qu’est devenue cette pratique dans le conseil d’administration, le conseil de classe, le conseil de quartier, etc. ? Des milliers de conseillers travaillent parmi nous. Est-ce le règne des spécialistes, des experts, ou est-ce un autre phénomène, manifesté sous des noms différents : aide, accompagnement, tutorat, mentorat, coaching, counseling ? « Tenir conseil » est une activité qui nous concerne tous, là où nous vivons et travaillons. Il n’y a jamais eu autant d’urgence et d’importance à tenir conseil pour faire face à l’événement et à l’urgence pour : s’approprier l’information et le savoir ; fonder les décisions ; créer, innover ; accompagner les changements ; l’art de se conduire ; l’art de participer (conseil de groupe) ; l’art de transcender, de donner sens à nos actes, à nos travaux ; créer de l’intelligence collective, une citoyenneté active.Mais en même temps, quel est l’espace public du conseil : marché ? Contrainte ? Volontariat ? Si nous ne voulons ni le conseillisme d’Etat, ni la conseillite libérale, que faire ?