bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate change via CO2 drawdown from astrophysically initiated atmospheric ionization?
Authors: Melott Adrian L. , Thomas Brian C. , Fields Brian D. 
Published: May 2020

AbstractMotivated by the occurrence of a moderately nearby supernova near the beginning of the Pleistocene, possibly as part of a long-term series beginning in the Miocene, we investigated whether nitrate rainout resulting from the atmospheric ionization of enhanced cosmic ray flux could have, through its fertilizer effect, initiated carbon dioxide drawdown. Such a drawdown could possibly reduce the greenhouse effect and induce the climate change that led to the Pleistocene glaciations. We estimate that the nitrogen flux enhancement onto the surface from an event at 50 pc would be of order 10%, probably too small for dramatic changes. We estimate deposition of iron (another potential fertilizer) and find it is also too small to be significant. There are also competing effects of opposite sign, including muon irradiation and reduction in photosynthetic yield caused by UV increase from stratospheric ozone layer depletion, leading to an ambiguous result. However, if the atmospheric ionization induces a large increase in the frequency of lightning, as argued elsewhere, the amount of nitrate synthesis should be much larger, dominate over the other effects and induce the climate change. More work needs to be done to clarify the effects on lightning frequency.
Does Social Content Influence the Subjective Evaluation of Affective Pictures?
Authors: Kosonogov Vladimir , Martínez-Selva José M. , Torrente Ginesa , Carrillo-Verdejo Eduvigis , Sánchez-Navarro Juan 
Published: May 2020

Abstract
This study explored the effect of the perceived social content of affective pictures on the subjective evaluation of affective valence and arousal. For this purpose, we established three categories of social content (pictures without people, with one person and with two or more people). A sample of 161 subjects rated 200 pictures varying in affective valence (unpleasant, neutral, and pleasant), arousal and social content. Results of two-factor analysis of variance, F(4, 157) = 71.7, p < .001, η
p
2
= .31, showed that perceived social content influenced the ratings of affective valence, specially for unpleasant pictures, with the greatest social content (two or more people) leading subjects to rate unpleasant pictures with the lowest ratings (all pairwise comparisons’ p < .001). Regarding arousal, F(4, 157) = 64.0, p < .001, η
p
2
= .29), the higher the social content, the higher the arousal ratings, but only for pleasant (all pairwise comparisons’ p < .007) and unpleasant (all pairwise comparisons’ p < .001) pictures. Overall, this study demonstrated an effect of the perceived social content on the subjective evaluation of affective valence and arousal of emotional stimuli.
Two‐Year Observations of the Jupiter Polar Regions by JIRAM on Board Juno
Authors: Adriani A. , Bracco A. , Grassi D. , Moriconi M. L. , Mura A. , Orton G. , Altieri F. , Ingersoll A. , Atreya S. K. , Lunine J. I. , Migliorini A. , Noschese R. , Cicchetti A. , Sordini R. , Tosi F. , Sindoni G. , Plainaki C. , Dinelli B. M. , Turrini D. , Filacchione G. , Piccioni G. , Bolton S. J. 
Published: May 2020

AbstractWe observed the evolution of Jupiter's polar cyclonic structures over two years between February 2017 and February 2019, using polar observations by the Jovian InfraRed Auroral Mapper, JIRAM, on the Juno mission. Images and spectra were collected by the instrument in the 5‐μm wavelength range. The images were used to monitor the development of the cyclonic and anticyclonic structures at latitudes higher than 80° both in the northern and the southern hemispheres. Spectroscopic measurements were then used to monitor the abundances of the minor atmospheric constituents water vapor, ammonia, phosphine, and germane in the polar regions, where the atmospheric optical depth is less than 1. Finally, we performed a comparative analysis with oceanic cyclones on Earth in an attempt to explain the spectral characteristics of the cyclonic structures we observe in Jupiter's polar atmosphere.
The future of cancer immunotherapy: microenvironment-targeting combinations
Authors: Murciano-Goroff Yonina R. , Warner Allison Betof , Wolchok Jedd D. 
Published: May 2020

AbstractImmunotherapy holds the potential to induce durable responses, but only a minority of patients currently respond. The etiologies of primary and secondary resistance to immunotherapy are multifaceted, deriving not only from tumor intrinsic factors, but also from the complex interplay between cancer and its microenvironment. In addressing frontiers in clinical immunotherapy, we describe two categories of approaches to the design of novel drugs and combination therapies: the first involves direct modification of the tumor, while the second indirectly enhances immunogenicity through alteration of the microenvironment. By systematically addressing the factors that mediate resistance, we are able to identify mechanistically-driven novel approaches to improve immunotherapy outcomes.
Selenium-deficient diet induces necroptosis in the pig brain by activating TNFR1 via mir-29a-3p
Authors: Cui Jiawen , Liu Honggui , Xu Shiwen 
Published: May 2020

Abstract
Selenium (Se) deficiency is one of the crucial factors related to nervous system disease and necroptosis. MicroRNAs (miRNAs) play vital roles in regulating necroptosis. However, the mechanism of Se deficiency-induced necroptosis in the pig brain tissue and the role that miRNAs play in this process are unclear. Therefore, in this study, in vitro and pig models of Se deficiency were replicated, and electron microscopy, quantitative real-time polymerase chain reaction (qRT-PCR) and western blot assays were performed. The results showed that brain cells typically undergo necrotic changes, and that Se deficiency suppresses mir-29a-3p, which increases the levels of TNFRSF1A (TNFR1). Subsequently, a distinct increase in the necroptosis markers (RIPK1, RIPK3, and MLKL) and an evident decrease in caspase 8 was observed. And the expression of 10 selenoproteins was decreased. Moreover, the in vitro experiments showed that the expression of mir-29a-3p decreased as the Se content in the medium decreased and the application of an mir-29a-3p inhibitor increased the number of necrotic cells and the accumulation of ROS, and these effects were inhibited by necrostatin-1 (Nec-1) and N-acetyl-cysteine (NAC), respectively. Taken together, we proved that Se deficiency induced necroptosis both in vitro and in vivo through the targeted regulation of TNFR1 by mir-29a-3p in the pig brain.
PET/CT in der Strahlentherapie
Authors: Krempien Robert , Münter Marc , Dresel Stefan 
Published: May 2020

ZusammenfassungDas therapeutische Konzept einer suffizienten Strahlentherapie ist die Applikation einer ausreichend hohen therapeutischen Dosis im anvisierten Zielvolumen bei gleichzeitiger maximaler Schonung des umgebenden Normalgewebes. Es zeigt sich jedoch mehr und mehr, dass die traditionellen Anatomie-basierten Schnittbildgebungen (CT, MRT) die Tumorausdehnung häufig über- oder unterbewerten. Seit der Einführung der Positronen-Emissions-Tomografie (PET) in die klinische Routine wird angestrebt, die morphologische Basis der Bestrahlungsplanungs-CT durch die funktionellen Informationen der PET zu ergänzen und somit zu einer biologisch funktionellen Bestrahlungsplanung zu gelangen. Durch eine präzise Koregistrierung der funktionellen, metabolischen Daten mit den für die Bestrahlungsplanung erforderlichen anatomischen Informationen aus den CT-Aufnahmen kommt die PET/CT-Technik den Anforderungen der Hochpräzisionsbestrahlung entscheidend entgegen. Klinische Studien bei nahezu allen Tumorentitäten zeigen einen erheblichen Einfluss der PET/CT auf die Konturierung der Zielvolumina. Erhebliche Änderungen zeigen sich in 20 % bis über 50 % der Fälle gegenüber rein CT-basierten Konturierungen. Im Folgenden haben wir die wesentlichen Daten in Bezug auf Staging und Zielvolumendefinition und soweit vorhanden auf Therapieansprechen zusammengefasst.
Blasenkarzinom − Komplikationen der Harnableitung
Authors: Pfister David , Niegisch Günter 
Published: May 2020

ZusammenfassungAuch heute noch stellt die radikale Zystektomie mit Anlage einer Harnableitung einen der komplikationsträchtigsten Eingriffe in der Uro-Onkologie dar. Insbesondere im Langzeitverlauf, aber auch perioperativ spielen dabei durch die Harnableitung bedingte Probleme eine wesentliche Rolle.Perioperativ stehen dabei im Wesentlichen gastrointestinale Probleme wie etwa ein Ileus, aber auch Infekte und frühe Komplikationen der unterschiedlichen Anastomosen im Vordergrund. Während ein Ileus ebenso wie perioperative Infekte i. d. R. medikamentös behandelt werden können, erfordern Insuffizienzen der intestinalen Anastomose regelhaft und Insuffizienzen der ureterointestinalen Anastomosen häufig operative Revisionen.Im Langzeitverlauf können Narbenbildungen zu chronischen Harnabflussbehinderungen und bei kontinenten Harnableitungen zur Steinbildung führen und ebenso wie parastomale Hernien weitere Therapien erforderlich machen. Funktionelle Darmprobleme können die Lebensqualität der Patienten nachhaltig beeinflussen.Durch eine verbesserte Vorbereitung präoperativ und die begleitenden Maßnahmen während des stationären Aufenthalts können nicht operationsbedingte Komplikationen signifikant reduziert werden.Die Zystektomie mit der therapieassoziierten Morbidität ist ein Paradebeispiel für eine zentrumsbasierte Operation um Komplikationen sowohl perioperativ als auch im weiteren Follow-up zu reduzieren.
Conceptual Design, Implementation, and Evaluation of Generic and Standard-Compliant Data Transfer into Electronic Health Records
Authors: Blitz Rogério , Dugas Martin 
Published: May 2020

Abstract
Objectives The objective of this study is the conceptual design, implementation and evaluation of a system for generic, standard-compliant data transfer into electronic health records (EHRs). This includes patient data from clinical research and medical care that has been semantically annotated and enhanced with metadata. The implementation is based on the single-source approach. Technical and clinical feasibilities, as well as cost-benefit efficiency, were investigated in everyday clinical practice.
Methods Münster University Hospital is a tertiary care hospital with 1,457 beds and 10,823 staff who treated 548,110 patients in 2018. Single-source metadata architecture transformation (SMA:T) was implemented as an extension to the EHR system. This architecture uses Model Driven Software Development (MDSD) to generate documentation forms according to the Clinical Data Interchange Standards Consortium (CDISC) operational data model (ODM). Clinical data are stored in ODM format in the EHR system database. Documentation forms are based on Google's Material Design Standard. SMA:T was used at a total of five clinics and one administrative department in the period from March 1, 2018 until March 31, 2019 in everyday clinical practice.
Results The technical and clinical feasibility of SMA:T was demonstrated in the course of the study. Seventeen documentation forms including 373 data items were created with SMA:T. Those were created for 2,484 patients by 283 users in everyday clinical practice. A total of 121 documentation forms were examined retrospectively. The Constructive cost model (COCOMO II) was used to calculate cost and time savings. The form development mean time was reduced by 83.4% from 3,357 to 557 hours. Average costs per form went down from EUR 953 to 158.
Conclusion Automated generic transfer of standard-compliant data and metadata into EHRs is technically and clinically feasible, cost efficient, and a useful method to establish comprehensive and semantically annotated clinical documentation. Savings of time and personnel resources are possible.
A subtitling stalemate
Authors: McKenzie Rory 
Published: May 2020

Abstract

The Dark Horse (2014) is a highly successful New Zealand film that exemplifies a strong
multilingual and multicultural landscape where the Māori language and cultural concepts, as well as specific examples of New
Zealand English co-exist within the one film. This linguistic and cultural complexity is a key part to the film, therefore
retaining this in a translation becomes a challenging responsibility for the subtitler. This article first introduces the
restrictions and intricacies of subtitling in general, and then analyses specific scenes from the commercial Italian subtitled
version of The Dark Horse, highlighting the translation choices made by the subtitler when confronted with
challenges pertaining to scenes involving multilingualism (in the form of English and Māori), culturally specific terminology (the
use of New Zealand English idioms), as well as the representation of register for children from low socio-economic backgrounds.
Alternative subtitles are proposed that seek to better represent the richness of the source text’s language and cultural
references.
Depth-dose measurement corrections for the surface electronic brachytherapy beams of an Esteya® unit: a Monte Carlo study
Authors: Valdes-Cortez Christian , Ballester Facundo , Vijande Javier , Gimenez Vicent , Gimenez-Alventosa Vicent , Perez-Calatayud Jose , Niatsetski Yury , Andreo Pedro 
Published: May 2020

Abstract
Three different correction factors for measurements with the parallel-plate ionization chamber PTW T34013 on the Esteya electronic brachytherapy unit have been investigated. This chamber type is recommended by AAPM TG-253 for depth-dose measurements in the 69.5 kV x-ray beam generated by the Esteya unit.
Monte Carlo simulations using the PENELOPE-2018 system were performed to determine the absorbed dose deposited in water and in the chamber sensitive volume at different depths with a Type A uncertainty smaller than 0.1%. Chamber-to-chamber differences have been explored performing measurements using three different chambers. The range of conical applicators available, from 10 to 30 mm in diameter, has been explored.
Using a depth-independent global chamber perturbation correction factor without a shift of the effective point of measurement yielded differences between the absorbed dose to water and the corrected absorbed dose in the sensitive volume of the chamber of up to 1% and 0.6% for the 10 mm and 30 mm applicators, respectively. Calculations using a depth-dependent perturbation factor, including or excluding a shift of the effective point of measurement, resulted in depth-dose differences of about ± 0.5% or less for both applicators. The smallest depth-dose differences were obtained when a shift of the effective point of measurement was implemented, being displaced 0.4 mm towards the center of the sensitive volume of the chamber. The correction factors were obtained with combined uncertainties of 0.4% (k = 2). Uncertainties due to chamber-to-chamber differences are found to be lower than 2%.
The results emphasize the relevance of carrying out detailed Monte Carlo studies for each electronic brachytherapy device and ionization chamber used for its dosimetry.
Zigzag approach to higher key rate of sending-or-not-sending twin field quantum key distribution with finite-key effects
Authors: Jiang Cong , Hu Xiao-Long , Xu Hai , Yu Zong-Wen , Wang Xiang-Bin 
Published: May 2020

Abstract
Odd-parity error rejection (OPER), in particular the method of actively odd parity pairing (AOPP), can drastically improve the asymptotic key rate of sending-or-not-sending twin-field (SNS-TF) quantum key distribution (QKD). However, in practice, the finite-key effects have to be considered for the security. Here, we propose a zigzag approach to verify the phase-flip error of the survived bits after OPER or AOPP. Based on this, we can take all the finite-key effects efficiently in calculating the non-asymptotic key rate. Numerical simulation shows that our approach here produces the highest key rate over all distances among all existing methods, improving the key rate by more than 100% to 3000% in comparison with different prior art methods with typical experimental setting. These verify the advantages of the AOPP method with finite data size. Also, with our zigzag approach here, the non-asymptotic key rate of SNS-TF QKD can by far break the absolute bound of repeater-less key rate with whatever detection efficiency. We can even reach a non-asymptotic key rate more than 40 times of the practical bound and 13 times of the absolute bound with 1012 pulses.
Protected superconductivity at the boundaries of charge-density-wave domains
Authors: Leridon Brigitte , Caprara Sergio , Vanacken J , Moshchalkov V V , Vignolle Baptiste , Porwal Rajni , Budhani R C , Attanasi Alessandro , Grilli Marco , Lorenzana José 
Published: May 2020

Abstract
Solid 4He may acquire superfluid characteristics due to the frustration of the solid phase at grain boundaries. Here, introducing a negative-U generalized Hubbard model and a coarse-grained semiclassical pseudospin model, we show that an analogous effect occurs in systems with competition among charge-density-waves (CDW) and superconductivity in the presence of disorder, as cuprate or dichalcogenide superconductors. The CDW breaks apart in domains with topologically protected filamentary superconductivity at the interfaces. Our transport measurements, carried out in underdoped La2−x
Sr
x
CuO4, with the magnetic field acting as a control parameter, are shown to be in excellent agreement with our theoretical prediction. Assuming superconductivity and CDW phases have similar energies, at intermediate temperatures, the magnetic field drives the system from a fluctuating superconductor to a CDW as expected in the clean limit. Lowering the temperature, the expected clean quantum critical point is avoided and a filamentary phase appears, analogous to ‘glassy’ supersolid phenomena in 4He. The transition line ends at a second quantum critical point at high-fields. Within our scenario, the filamentary superconducting phase is parasitic with CDW and bulk superconducting phases playing the role of primary competing order parameters.
Cat swarm optimization and Levenberg-Marquardt for model identification and prediction identification and prediction tuberculosis disease spreading
Authors: Nuari A , Damayanti A , Pratiwi A B 
Published: May 2020

Abstract
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis and can cause death. Based on the prevalence rate, Indonesia ranks third after India and China as the countries with the highest number of TB sufferers in the world. Models identification and prediction are needed to minimize and anticipate problems that can occur. In applying the model, Cat Swarm Optimization and the Levenberg-Marquardt are used. The purpose of this study is to obtain the prediction result based on the model identification in TB disease spreading using a swarm optimization algorithm and Levenberg-Marquardt. The identification is intended to analyze the spread of TB disease based on actual data. The process begins with estimating the parameters in the model using the Cat Swarm Optimization algorithm. After getting the optimal parameters, the acquisition of the model uses Levenberg-Marquardt. Based on the implementation of the program on the spread of TB disease in East Java in the period of the first quarter of 2002 to the fourth quarter of 2017, the MSE of training and prediction process were 0.000225563 and 0.0085307, respectively. The MSE value from the prediction process shows that the Cat Swarm Optimization and Levenberg-Marquardt can be used to identify models and predict the spread of tuberculosis.
Clustering of fish freshness using discrete wavelet transform and Kohonen self organizing map
Authors: Anvy J , Damayanti A , Pratiwi A B 
Published: May 2020

Abstract
Fish freshness is one of the criteria of fish, whether it is good or not for consumption. A fish can be categorized as a fresh condition if it looks like alive fish. The observation about level of fish freshness generally can be checked directly through the human senses, but along with the development of technology, fish freshness observation can detected using a technology. One of them is by utilizing digital image processing. The purpose of this research is to cluster fish into three clusters namely fresh, not fresh, and rotten using the discrete wavelet transformation and Kohonen Self Organizing Map (SOM). Stages of clustering of the fish freshness are pre-processing, feature extraction, and clustering. At the pre-processing stage, RGB to grayscale images are converted. After pre-processing, the next stage is image decomposition in pre-processing result which is applied using Discrete Wavelet Transform (DWT) Haar level 3 and takes the statistical parameters of the mean and standard deviation from the horizontal detail coefficient. Mean and standard deviation obtained are used as the input in clustering process using Kohonen SOM. Based on the test result, it showed that the percentage of fish was clustered correctly is 92,857%.
On Cartesian product of intuitionistic Q-fuzzy ideal on ordered semigroup
Authors: Hidayat N , Yanti I , Fitriah Z , Miftah D , Anam S , Rahman S I , Hidayat F 
Published: May 2020

AbstractIntuitionisticQ-fuzzy set is one of the results of the development of the concept of fuzzy sets by entering the degree of membership and nonmembership. In this paper, we would like to discuss the process of forming Cartesian product from intuitionisticQ-fuzzy ideal on ordered semigroup. Some of the properties of the Cartesian product are created and proven.
Jacobson graph construction of ring

ℤ3n

, for n>1
Authors: Novictor A , Susilowati L , Fatmawati  
Published: May 2020

Abstract
A group is called a ring if the group is a commutative under addition operation and satisfy the distributive and assosiative properties under multiplication operation. Suppose R is a commutative ring with non-zero identity, U is the unit of R, and J(R) is a Jacobson radical. Jacobson graph of a ring R denoted by ℑ
R
is a graph with a vertex set is R\J(R) dan edge set is {(a, b)| 1 − ab ∉ U}. The purpose of this research is to construct a Jacobson graph of ring Z
3

n
with n > 1. The results show that Jacobson graph of ring Z
3

n
is a disconected graph with two components.
The validity of the properties of real numbers set to hyperreal numbers Set
Authors: Masithoh R , Guswanto B H , Maryani S 
Published: May 2020

Abstract
This research discusses the validity of the properties of real numbers set to hyperreal numbers set, i.e. algebraic, ordered, and completeness properties, by using a finitely additive measure. This finitely additive measure is a map from the power set of natural numbers set onto set {0,1}. The subset of natural numbers set has measure zero if it’s finite and one if it’s infinite. The set of hyperreal numbers is constructed from equivalence classes of the set of all sequences of real numbers by using a relation involving the finitely additive measure, that is, two sequences of real numbers are said to be related if and only if those two sequences are the same almost everywhere. In the hyperreal numbers set, there exist infinitesimal numbers besides 0. Infinitesimal number is a number which is less than any positive real number and greater than any negative real number. So, in hyperreal number set, there are some smallest positive numbers. The results show that the hyperreal numbers set is an ordered and complete field.