bluuebunny/crossref_metadata_2025_split huggingface dataset:
0206 Sleep Opportunity and Duration are Related to Risk Injury in Elite Athletes
Authors: Shaw L , Cohen R , Altman Y , Eyal S , Baharav A 
Published: May 2020

Abstract

Introduction
Sleep is essential to musculoskeletal recovery, acquisition of new skills and emotional regulation in athletes. Insufficient sleep is detrimental to performance. Recent publications indicate that sleep duration is related to risk for injury in young athletes. We aimed at analyzing the relation between sleep opportunity and duration and the likelihood of an injury among adult elite athletes.

Methods
We studied 7,237 nights recorded with the Sleeprate application by 71 adult elite athletes from diverse sports, during the period September 2018-October 2019. Night recordings included perceived and measured sleep parameters. In addition, athletes reported their previous day nap duration, injuries and illness status. Out of the total number of nights, 4,205 included reported injury status with no injury and no illness for the previous night. Nightly total time in bed (TIB), TIB including reported naps (TIB24hr) and measured total sleep time (TST) were examined.

Results
Average TIB was significantly shorter (508±77 minutes, mean±STD) in healthy days preceding injuries than in healthy days preceding days with no injury (525±70 minutes, p&lt;.001). Similar results were found when comparing the TIB24hr (injury: 517±83 minutes, no injury: 543±76 minutes, p&lt;.001) and TST (injury: 443±72 minutes, no injury: 457±69 minutes, p&lt;.001).

Conclusion
Average sleep opportunities of the elite athletes in this study were in accordance with their age and workouts load. The time athletes allow themselves as an opportunity for sleep is inversely correlated to the chances of developing an injury. These findings corroborate published research regarding sleep duration and risk of injury in athletes, yet our findings are based on real life data of elite athletes, and demonstrate the importance of sleep as part of the elite or professional athlete’s routine, suggesting that even as little as around 20 minutes of added sleep may be efficient in preventing injury.

Support
N/A
0213 The Association Between Work-Related Job Demands and Daytime Impairment in Professional Firefighters
Authors: Soto P , Dzierzewski J M , Dautovich N D , Ravyts S G , Perez E , Donovan E K 
Published: May 2020

Abstract

Introduction
Sleep is an important predictor of daytime functioning and is impaired in first responders. The present study investigated whether job demands were associated with daytime impairment in professional firefighters. We hypothesized that the frequency of emergency calls would predict daytime impairment above and beyond years of service, sleep apnea risk, and sleep duration.

Methods
Participants were 267 (251 males; mean age=41.94) firefighters from the Richmond, Virginia Fire Department who completed pen-and-paper surveys in small groups assessing sleep duration (Pittsburgh Sleep Quality Index; PSQI), sleep apnea risk (STOP-BANG), job demands (number of emergency calls received per day), and sleep-related impairment (Patient Reported Outcomes Measurement Information System 8-item short-form; PROMIS). A three block hierarchical regression was used to assess the contribution of job demands to daytime impairment.

Results
The final model significantly predicted sleep-related daytime impairment, F(4,260)=11.51, p&lt;.001, R2=.15. Each block in the model accounted for significant change in variance, years of service and sleep apnea risk (R2=.05), sleep duration (∆R2=.08), number of calls (∆R2=.01). Number of emergency calls significantly predicted daytime impairment (β=.14) above and beyond number of years of service (β= -.24), sleep duration (β= -.29), and sleep apnea risk (β=.03).

Conclusion
With 2–18 emergency calls per 24-hour period, the results suggest that job-related demands are a unique contributor to daytime functioning in professional firefighters. As such, it will be important for interventions aimed at improving sleep in professional firefighters to incorporate information unique to the profession (i.e., job specific demands and intensity of work) as specific treatment factors.

Support
This work was supported by the National Institute on Aging (K23AG049955, PI: Dzierzewski).
0217 Adolescents’ Evening Preference is Associated with Specific Sleep Hygiene Behaviours
Authors: Gauthier-Gagne G , Dimakos J , Somerville G , Boursier J , Gruber R 
Published: May 2020

Abstract

Introduction
Circadian tendencies are associated with individual differences in preferred timing of behaviour. Sleep hygiene encompasses a variety of habits that are necessary for healthy. Given the later bedtimes of individuals with evening circadian preferences, more time is spent being awake in the evening and this could be associated with increased or longer engagement in poor sleep hygiene. Specific sleep hygiene practices that are common in adolescents with high evening preferences may therefore be a target to improve sleep. However, the relationship between specific sleep hygiene behaviours and circadian preferences in adolescents has not been examined. The objective of this study was to examine the associations between circadian preference and specific domains of sleep hygiene behavior.

Methods
127 adolescents (86 female) between 13 and 18 years old (M = 14.83, SD = 1.20) participated in the study. Circadian preferences were measured by the Morningness-Eveningness subscale of the School Sleep Habits Survey. Sleep hygiene was measured using the Adolescent Sleep Hygiene Scale (ASHS).

Results
Higher eveningness scores were significantly negatively associated with the ASHS physiological, behavioural arousal, cognitive emotional arousal, sleep environment, sleep stability, daytime sleep, substances use factors (r = -.20, p = &lt;.05, r = -.27, p = &lt;.01, r = -.32, p = &lt;.01, r = -.18, p = &lt;.05, r = -.41, p = &lt;.01, r = -.28, p = &lt;.01, r = 0.20, p = &lt;.05 respectively) and with total sleep hygiene score (r = -.45, p = &lt;.01).

Conclusion
Higher eveningness preferences in adolescents is significantly associated with poorer sleep hygiene in all domains with the exception of bedtime routine. Behavioural arousal, cognitive emotional, and sleep stability domains show the strongest inverse correlations. These findings could be used to inform the development of tailored sleep health interventions for adolescents with strong evening tendencies

Support
Social Sciences and Humanities Research Council (SSHRC) support for Dr. Reut Gruber.
0226 Sleep Duration and Symptoms Associated with Race/Ethnicity in Elite Collegiate Athletes
Authors: Ramsey T , Athey A , Auerbach A , Turner R , Williams N , Jean-Louis G , Killgore W D , Wills C C , Grandner M A 
Published: May 2020

Abstract

Introduction
Previous studies have documented sleep disparities in the general population. Given the increased interest in sleep among athletes, and the degree to which demographics and schedules among athletes differ from the general population, this analysis aims to examine the relationship between race/ethnicity and sleep duration and symptoms among elite college athletes.

Methods
Data were obtained from N=189 Division-1 collegiate athletes across a wide range of sports played. Race/ethnicity was self-reported and categorized as Non-Hispanic White, Black/African-American, Hispanic/Latino, Asian, and American Indian/Alaskan Native. Outcomes of interest included self-reported typical sleep duration (in hours), CESD depression score, and frequency of sleep symptoms, assessed using items from the Sleep Disorders Symptom Check List (difficulty falling asleep, difficulty staying asleep, early morning awakenings, tiredness, sleepiness, loud snoring, choking/gasping, fragmentation, hypnogogic/pompic hallucinations, sleep paralysis, and nightmares). Sleep duration and depression were evaluated with linear regression, and symptoms were evaluated as ordinal. Covariates included age and sex.

Results
Compared to Non-Hispanic Whites, Blacks/African-Americans reported less sleep (B=-0.80, p&lt;0.0005), more depression (B=2.85, p=0.046), more difficulty maintaining sleep (oOR=2.12, p=0.034), early morning awakenings (oOR=3.15, p=0.001), and sleepiness (oOR=2.11, p=0.048); Hispanic/Latinos reported more hypnogogic/pompic hallucinations (oOR=2.90, p=0.007), sleep paralysis (oOR=2.72, p=0.026), and nightmares (oOR=2.22, p=0.035); Asians reported more depression (B=4.46, p=0.028), sleepiness (oOR=5.06, p=0.003), loud snoring (oOR=4.71, p=0.018), and sleep paralysis (oOR=3.57, p=0.031); and American Indians/Alaskan Natives reported less sleep (B=-1.00, p=0.018).

Conclusion
Racial/ethnic differences in sleep duration and sleep symptoms were seen among athletes. Future studies will be needed to replicate and further explain these findings.

Support
The REST study was funded by an NCAA Innovations grant. Dr. Grandner is supported by R01MD011600
0238 Campus Food Pantry Assistance is Related to Better Physical And Mental Health Through Adequate Sleep Among College Students in a Public University System
Authors: Martinez S , Kalaydjian S , Ritchie L , Nazmi A , Prather A 
Published: May 2020

Abstract

Introduction
Food insecurity is an issue among students in higher education and has been linked to insufficient sleep, and poor mental and general health. College campuses have quickly responded by establishing campus food pantries. However, the extent to which campus food pantries are ameliorating the impacts of food insecurity is unknown.

Methods
Online survey data were collected from a cross-sectional sample of 1,855 students who were food pantry users in the 10-campus UC system. Students were asked to report their number of visits to a food pantry in the past month, and to rate their general health, depressive symptoms, and number of days of enough sleep (in a week) before and after food pantry access. Changes in days of enough sleep, depressive symptoms and general health were computed. Demographic characteristics were obtained from institutional data. Path analysis was used to examine direct and indirect pathways from food pantry use to depressive symptoms and general health through enough sleep days, controlling for workstudy receipt, Pell grant receipt and family income.

Results
Students on average were 21.7 years old (SD= 3.5), and had more days of adequate sleep (25%), and improved depressive symptoms (43%) and general health (31%) after obtaining services from a campus food pantry. An increase in monthly food pantry use was directly related to a decrease in depressive symptoms (β= 0.08, p&lt;0.001) and an increase in general health (β= 0.07, p=0.001). Additionally, an increase in food pantry use related to an increase in getting more days of enough sleep (β=0.07, p=0.001), which in turn positively related to a decrease in depressive symptoms (β=0.18, p&lt;0.001) and improved general health (β=0.24, p&lt;0.001).

Conclusion
Food pantry use had a positive relationship with student health outcomes, and enough sleep days played an important mediating role. Findings suggest that emergency food access may have a positive impact on student health outcomes.

Support
This study was funded by the UC Campus Basic Needs Committees.
0272 Effects of Gestational Sleep Restriction on Maternal Behavior in Rodents: A Systematic Review and Meta-Analysis
Authors: Pires G N , Baenninger T , Mello V , Andersen M L , Tufik S 
Published: May 2020

Abstract

Introduction
Sleep restriction during pregnancy is related with postpartum depression in clinical settings. Preclinical studies have been conducted in rodent models of maternal behavior, intending to evaluate the mechanisms behind this relationship, but have raised inconsistent data so far. Our aims were to perform a preclinical meta-analysis, evaluating the actual effects or prenatal sleep restriction on maternal behavior in rodents.

Methods
A bibliographic search was conducted in Pubmed, Scopus, Web of Science, Psychinfo and Lilacs. Search strategy encompassed three domains: sleep restriction during pregnancy (as intervention), maternal behavior (as outcome) and experimentation animals (as population). Studies were first selected based on titles and abstracts, followed by full text analysis and data extraction. Individual effect size for each articles was calculated using standardized mean difference and meta-analysis was conducted using a DerSimonian and Laird random effects model.

Results
144 articles were included in our initial data screening. Sample was reduced to six records after screening. A meta-analysis was performed, including data from two maternal behavior tests (pup retrieval test and ethogram-based analyses). A total of 115 animals were included. Meta-analysis showed that sleep restriction during pregnancy have no significant effects on maternal behavior.

Conclusion
Clinical studies and meta-analysis have shown that sleep restriction and disorders during pregnancy increase risk for postpartum depression. However, preclinical studies fail to corroborate these results, as sleep restriction during pregnancy does not reduce maternal behavior in rodents. The presence of negative effects in women and the maintenance of normal maternal behavior levels in rodents under comparable intervention demonstrate that other factors might mediate this relationship (among which, sociocultural factors might play a role). The maintenance of maternal behavior seems to be an adaptive behavior, assuring the suitability and survival of the litter, even in face of environmental stresses.

Support
AFIP, FAVC, CNPq, FAPESP
0276 Does Losing Sleep Unleash Anger?
Authors: Krizan Z , Miller A , Hisler G 
Published: May 2020

Abstract

Introduction
Sleeping is understood as essential to affective function, yet little is known about how sleep shapes more specific and contextualized emotional responses besides anxiety and depression, such as anger. Anger itself involves arousal and can disrupt sleep. To examine the causal role of sleep in anger, a daily-diary study and an experimental study tested whether shortened sleep amplifies angry feelings, while exploring mediating mechanisms of this influence.

Methods
The daily-diary study (N = 202) collected daily reports of last-night’s sleep, daily stressors, and state anger across one month from college students, examining sleep and anger within everyday life. The experimental laboratory study (N = 147 community residents) examined changes in anger experienced during aversive noise following random assignment to either at-home sleep restriction (by about 5 hours across 2 nights), or to individuals’ regular schedule.

Results
In the daily-diary study, individuals experienced more anger on days following less sleep than their usual, with half of this effect attributed to the increased frequency of stressors experienced on such days, and somewhat independently from the effect of sleep duration on negative affect more generally. In the experimental study, well-slept individuals adapted to noise and reported less anger and negative affect after 2 days. In contrast, sleep-restricted individuals exhibited higher and increased anger responses. The impact of sleep restriction on anger held even after accounting for negative emotions more generally. Subjective sleepiness accounted for most of the experimental effect of sleep loss on anger.

Conclusion
Together, these results provide compelling evidence that lost sleep amplifies anger in both the laboratory and everyday life, while also pointing to short-term (subjective sleepiness) and mid-term (stress) mediators of these influences. The findings also point to the value of examining specific emotional reactions (and their regulation) in the context of sleep disruption, alongside affect more broadly.

Support
N/A
0301 Different Indices of Vigilant Attention During Sleep Deprivation: Evidence of Multiple Vigilance Constructs?
Authors: Lawrence-Sidebottom D , Hinson J M , Whitney P , Honn K A , Van Dongen H 
Published: May 2020

Abstract

Introduction
Total sleep deprivation (TSD) causes profound vigilant attention deficits, with large, trait-like individual differences, as evidenced convincingly by response lapses on the psychomotor vigilance test (PVT). There is debate, however, about the role of vigilant attention deficits in the effects of TSD on other speeded performance tasks besides the PVT. We addressed this issue by testing whether PVT response lapses are related to delays in responding to stimuli under strict deadlines in two decision making tasks.

Methods
N=54 healthy adults (aged 21-38y; 31 females) completed an in-laboratory TSD study. Following a 10h baseline sleep opportunity, cognitive testing occurred after 25h and 29h of TSD (09:00 and 13:00). Testing included an AX continuous performance task with switch (AX-CPTs), which is a dynamic decision making task requiring subjects to respond to a frequently occurring cue-probe combination; an identical pairs continuous performance task (CPT-IP), which is a 1-back go/no-go task; and a 10min PVT. Lapses (RTs&gt;500ms) on the PVT and target accuracy on the AX-CPTs and CPT-IP were calculated as indices of vigilant attention. Intraclass correlation coefficients (ICCs) were used to quantify the stability of individual differences, and absolute rank-order correlation (|ρ|) was used to compare the three indices.

Results
The stability of individual differences ranged from fair to substantial (PVT: ICC=0.44; AX-CPTs: ICC=0.73; CPT-IP: ICC=0.31). The rank-order correlation between the AX-CPTs and CPT-IP vigilant attention indices was relatively high (|ρ|=0.44), whereas correlations with PVT lapses were much lower (AX-CPTs: |ρ|=0.14; CPT-IP: |ρ|=0.04).

Conclusion
Individual differences during TSD were moderately stable for each index of vigilant attention, but the relationships between PVT lapses and the other indices were weak. This suggests that any or all of the indices considered here are not pure measures of vigilant attention, or that vigilant attention may constitute multiple, distinct constructs.

Support
CDMRP grant W81XWH-16-1-0319
0306 Corticotropin-Releasing Hormone Receptor 1 Gene Polymorphism Modulates Cognitive Flexibility Following Acute Stress and Total Sleep Deprivation
Authors: Satterfield B C , Anlap I , Esbit S L , Killgore W D 
Published: May 2020

Abstract

Introduction
Dynamic decision processes requiring flexible updating of information are impaired by stress and sleep loss, both of which activate the hypothalamic-pituitary-adrenal (HPA) stress response. Corticotropin-releasing hormone (CRH) initiates the HPA pathway. The CRH receptor (CRHR1) gene contains a single nucleotide polymorphism that modulates this response. We investigated whether cognitive flexibility is affected by CRHR1 polymorphism following a night of acute stress and total sleep deprivation (TSD).

Methods
N=46 healthy, young adults (21.8±3.4y; 21 females) participated in an in-laboratory 31h sleep deprivation study. Beginning at 19:30 until 07:30, the Maastricht Acute Stress Test (MAST) was administered every 4h. The MAST alternates a cold pressor task with an oral subtraction task five times in a single bout. At 29h wakefulness, subjects performed a novel go/no-go reversal learning task. Stimulus-response rules were presented at the beginning of the task, and subjects were asked to either respond or withhold a response to the presented stimuli while receiving accuracy feedback. Halfway through the task, the stimulus-response rules were reversed. Performance was assessed by discriminability index (d’), hit rate (HR), and false alarm rate (FAR). Saliva samples were collected immediately prior, immediately after, and 30min after each MAST and assayed for cortisol. One saliva sample from each subject was assayed for CRHR1 genotype.

Results
CRHR1 genotypes were in Hardy-Weinberg equilibrium (χ 2=2.97, p=0.08). Mixed effects ANOVA with fixed effects of CRHR1 genotype, pre/post-reversal, and their interaction found a significant CRHR1 by reversal interaction for d’ (F2,319=3.88, p=0.022) and HR (F2,319=3.16, p=0.044) following a night of stress and TSD. No such interaction was found at well-rested baseline (d’: F2,319=2.51, p=0.083; HR: F2,319=1.55, p=0.213). Subjects homozygous for the T allele had higher mean post-MAST cortisol levels (0.40±0.06 µg/dL) with better pre-reversal performance, but worse post-reversal performance compared to heterozygous and homozygous G allele carriers.

Conclusion
CRHR1 genotype modulates dynamic decision making following a night of acute stress and TSD. A higher cortisol stress response (T/T genotype) is beneficial to maintaining task relevant information (stability), but significantly impairs the ability to update task-relevant information following a change in situational demands (flexibility).

Support
CDMRP grant W81XWH-17-C-0088
0317 Impact of Recurrent Partial Sleep Loss Combined with Acute Exercise on Circulating and Adipose Tissue Levels of Leptin, Adiponectin and Ghrelin in Healthy Young Individuals
Authors: Schéle E , Dickson S , Benedict C , Cedernaes J 
Published: May 2020

Abstract

Introduction
Chronic sleep loss and aerobic exercise have opposing effects on body weight maintenance. The effects of sleep loss on circulating levels of the orexigenic hormone ghrelin and the anorexigenic hormone leptin have been extensively studied. In contrast, how these changes interact with acute exercise, and whether these changes are reflected at the tissue level, remains poorly understood.

Methods
In a randomized, 2 session, crossover design, 16 normal-weight young men were studied following three nights of partial sleep deprivation (4.25 hr sleep opportunity each night) and three nights of normal sleep (8.5-h sleep opportunity), monitored in a sleep laboratory. Each condition was followed by 30 min of intense morning ergometer cycling. Plasma levels of leptin and ghrelin, as well adipose tissue mRNA levels of leptin and adiponectin, were measured before and after each exercise intervention.

Results
In response to acute exercise, circulating levels of both leptin (ANOVA time effect: P&lt;0.001) and ghrelin (time: P&lt;0.001) decreased immediately (+15 min), and remained significantly lower +30, +60 and +240 min post exercise for leptin (all P&lt;0.05), and up until +30 min post exercise for ghrelin. These effects were seen regardless of sleep condition (ANOVA sleep condition: P&gt;0.10). In adipose tissue, mRNA expression of leptin and adiponectin was not different between the sleep conditions (ANOVA sleep condition: P&gt;0.10). In contrast, mRNA levels of leptin decreased (P=0.017), whereas adiponectin mRNA increased (P=0.010) 3.5 hours post vs. pre exercise. The decrease in leptin in response to exercise appeared to mainly occur following sleep loss (P=0.066) and not after normal sleep (P=0.38).

Conclusion
Our results suggest that both circulating and adipose tissue levels of appetite-regulating hormones are altered in response to acute aerobic exercise, in a manner that does not depend on prior sleep history. Whether these findings apply to older, female, or metabolically ill individuals - and whether they may differ in response to circadian misalignment, or evening exercise - remains to be established.

Support
The Swedish Society for Medical Research, the Swedish Society of Medicine, the Swedish Research Council and the Göran Gustafsson; Swedish Brain; Åke Wiberg and NovoNordisk Foundations.