bluuebunny/crossref_metadata_2025_split huggingface dataset:
FPGA oriented design method of Adjustable Arbiter Physical Unclonable circuit
Authors: Zhou Jinren 
Published: February 2020

AbstractIn this paper, the design principle of the Arbiter Physical Unclonable Function (APUF) based on the arbiter is studied, the existing problems are analyzed, and the problem of its delay asymmetry is studied. An adjustable APUF structure for FPGA platform is proposed, which includes three modules. To adjust the delay deviation of the two paths of traditional Apuf flexibly, it is implemented and verified on the actual FPGA, which proves its feasibility and superiority.
Intermittent subharmonic and chaos in parallel Buck converters with coupled interference signal
Authors: Wang Lili , Chen Junning 
Published: February 2020

Abstract
This paper studies intermittent instabilities in parallel power system. Taking parallel buck converters with coupled interference signals as an example, model and actual system are established. By numerical simulation, the nonlinear behaviours are captured under some conditions. Characteristics and mechanism of intermittency are depicted by nonlinear theory. In this paper, mappings time to parameter are established and discrete iterative mappings for nonlinear systems are derived. All the simulation results are consistent with the theoretical analysis results. The research method adopted in the paper is applicable for the other parallel powersystems. The conclusion can provide a reference for the parallel converters to maintain stable operation and serves as a theoretical basis for further optimization design and system control.
Research on abundance adaptive frequency control strategy of household temperature-control load
Authors: Song Shuang , Li Zhongwei , Liu Yong , Bai Ziyang 
Published: February 2020

Abstract
Based on the method of space state, state division of household temperature-control load group is proposed. State sequence method is used to analyze the influence of load group abundance on aggregated power. Based on the minimum cost and maximum flow algorithm, the temperature-control load group’s abundance recovery strategy is proposed, which could achieves the goal of fast and smooth recovery load group abundance. The simulation of household temperature-control load respond to the power system primary frequency adjustment is carried out under the circumstances of good abundance, excess abundance and lack of abundance. The simulation results show that the effect of temperature control load on the power grid primary frequency adjustment is fine. and the effectiveness of the proposed frequency adjustment control strategy is verified.
Equal Losses control strategy for all switches of intermediate frequency heating power supply
Authors: Deng Rui , Qin Qingliang 
Published: February 2020

Abstract
The energy loss of the switches of the lead legs and lag legs during the operation of the intermediate frequency heating power supply using the traditional full bridge control method has a certain difference, and the greater the power of the device, the more obvious the difference. This phenomenon seriously affects the reliability of high-power intermediate frequency heating power supplies. In this paper, the original full-bridge inverter drive is adjusted, and the conditions for implementing ZVS are analyzed. Finally, the equal losses control strategy for all switches is achieved by using the waveform generated by the FPGA controller.
Research on dead-reckoning based localization for cleaning robot
Authors: Wang Y , Zhang Z 
Published: February 2020

Abstract
The cleaning robot can perform cleaning tasks autonomously and intelligently, thus saving people from boring and heavy physical labour. Autonomous positioning is one of the indicators for intelligent level of cleaning robots. In this paper, dead-reckoning method based on encoder is adopted. The kinematics model of the robot is established to optimize the existing cleaning robot positioning method by using arc model. The positioning effect of the cleaning robot is tested by experiment. Through experiments, it is found that there are two main problems in the estimation of the track. One is that during the turning process, the calculation of the angle is affected by the slip, which causes a large deviation. Another is that the displacement deviation of linear motion gradually increases with the increase of the driving distance due to system error. Based on the above analysis, a positioning scheme is proposed. Gyro sensor and RFID tag are introduced to correct the angular deviation and assist positioning and improve the positioning accuracy of the cleaning robot.
Research on the Control Strategy of Maximum Energy Utilization and Disordered Disturbance Suppression in Distributed Generation System
Authors: Zhou Feng , Sun Shibo , Xu Mingyu , Hao Wenbo , Wang Bing , Wang Luxin , Jiang Peng 
Published: February 2020

AbstractThe ultimate goal of distributed renewable energy control is to minimize disorder disturbance to the power grid while ensuring maximum energy utilization. Taking wind power as an example, a coupling system using flywheel energy storage system to balance the output variables of wind power system was proposed while using hill climb searching (HCS) to maximize the utilization of wind energy. These methods can obtain stable DC output voltage. In the case of wind speed variation, as a limited capacity energy pool structure, flywheel energy storage system can ensure the maximum utilization of wind energy. Based on fully utilization of wind energy resources, the rapid and comprehensive compensation of wind power output can effectively smooth the output voltage of grid-connected wind power system, thus achieving the purpose of improving the power quality of grid-connected wind power system.
Practical Inverse Kinematic Solution Based on Calibrated Parameters Using in Engineering
Authors: Shi Guosong , Zhao Shuying , Lin Tianyu 
Published: February 2020

Abstract
Inverse kinematic (IK) problem is an essential problem in industrial robot control. In some high accuracy projects, the solution needs the robot act based on online sampled data rather than the pre-teached actions. It is necessary to reduce the absolute positioning error to complete these challenging projects. The IK solution is on the way there. This article simply introduces the standard IK solution based on robot KUKA R2700, points out the shortage of standard IK solution in enhancing the absolute positioning accuracy and develops an practical IK solution, PIKFCP, which is necessary in some measures.
High-throughput, multi-parametric, and correlative fluorescence lifetime imaging
Authors: Poudel Chetan , Mela Ioanna , Kaminski Clemens F 
Published: February 2020

Abstract
In this review, we discuss methods and advancements in fluorescence lifetime imaging microscopy that permit measurements to be performed at faster speed and higher resolution than previously possible. We review fast single-photon timing technologies and the use of parallelized detection schemes to enable high-throughput and high content imaging applications. We appraise different technological implementations of fluorescence lifetime imaging, primarily in the time-domain. We also review combinations of fluorescence lifetime with other imaging modalities to capture multi-dimensional and correlative information from a single sample. Throughout the review, we focus on applications in biomedical research. We conclude with a critical outlook on current challenges and future opportunities in this rapidly developing field.
Sr addition and its effect on the melt cleanliness of A356
Authors: Atakav Baturalp , Gürsoy Özen , Erzi Eray , Tur Kazim , Dispinar Derya 
Published: February 2020

Abstract
Strontium modification of Al–Si alloys has known to have several beneficial effects such as increased feedability, the formation of fibrous Si and increased mechanical properties. However, in the presence of Sr, during melting and holding durations, the oxide structure of the dross may change which leads to several problems during casting operations. In this work, the amount of Sr was changed and the melt was held for 1 h. Reduced Pressure Test (RPT) was used to asses melt quality change and it was found that cleanliness was increased due to the fading of Sr.
Performance comparison of solar radiation forecasting between WRF and LSTM in Gifu, Japan
Authors: de Araujo Jose Manuel Soares 
Published: February 2020

Abstract
Three months comparison of hourly solar radiation forecasting from 1st January to 31st March 2017 between Weather Research and Forecasting (WRF) mesoscale model and Long short-term memory (LSTM) algorithm is presented in this study. One-way grid nesting technique of the WRF model is applied for the simulation with a six-hourly input dataset downloaded from the National Oceanic and Atmospheric Administration - National Operational Model Archive and Distribution System (NOMADS) website. Three years’data of solar radiation from 1st January 2014 to 31st December 2016 are used as input data for Long Short Term Memory (LSTM) algorithm to simulate solar radiation. The results show the root mean square error of the LSTM algorithm is 310 W m−2 higher compared to 210 W m−2 from the WRF model. The MBE and the nMBE of the WRF model are obtained positive value 96 W m−2 and 9% compared to −101 W m−2 and −9% of LSTM for 2160 h prediction. Meanwhile, the performance error percentage of WRF is 19% lower compared to 28% of LSTM for the nRMSE error metric. Although this study found that the WRF model performed better and lower error compared to the LSTM algorithm, however, it also recommends the LSTM algorithm configuration can be used for long-term prediction.
Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of IL15
Authors: Bartlett David B , Duggal Niharika A 
Published: February 2020

Abstract

Introduction
ageing is accompanied by impairments in immune responses due to remodelling of the immune system (immunesenescence). Additionally, a decline in habitual physical activity has been reported in older adults. We have recently published that specific features of immunesenescence, such as thymic involution and naïve/memory T-cell ratio, are prevented by maintenance of a high level of physical activity. This study compares immune ageing between sedentary and physically active older adults.

Methods
a cross-sectional study recruited 211 healthy older adults (60–79 years) and assessed their physical activity levels using an actigraph. We compared T- and B-cell immune parameters between relatively sedentary (n = 25) taking 2,000–4,500 steps/day and more physically active older adults (n = 25) taking 10,500–15,000 steps/day.

Results
we found a higher frequency of naïve CD4 (P = 0.01) and CD8 (P = 0.02) and a lower frequency of memory CD4 cells (P = 0.01) and CD8 (P = 0.04) T cells in the physically active group compared with the sedentary group. Elevated serum IL7 (P = 0.03) and IL15 (P = 0.003), cytokines that play an essential role in T-cell survival, were seen in the physically active group. Interestingly, a positive association was observed between IL15 levels and peripheral CD4 naïve T-cell frequency (P = 0.023).

Discussion
we conclude that a moderate level of physical activity may be required to give a very broad suppression of immune ageing, though 10,500–15,000 steps/day has a beneficial effect on the naïve T-cell pool.
A decade of geriatric traumatic brain injuries in Finland: population-based trends
Authors: Posti Jussi P , Sipilä Jussi O T , Luoto Teemu M , Rautava Päivi , Kytö Ville 
Published: February 2020

Abstract

Background
we investigated trends of traumatic brain injury (TBI)-related hospitalisations, deaths, acute neurosurgical operations (ANO), and lengths of hospital stay (LOS) in patients aged ≥70 years in Finland using a population-based cohort.

Methods
nationwide databases were searched for all admissions with a TBI diagnosis as well as later deaths for persons ≥70 years of age during 2004–2014.

Results
the study period included 20,259 TBI-related hospitalisations (mean age = 80.7 years, men = 48.9%). The incidence of TBI-related hospitalisations was 283/100,000 person-years with an estimated overall annual increase of 2.9% (95% CI: 0.4–5.9%). There was an annual decrease of 2.2% in in-hospital mortality (IHM) in men (95% CI: 0.1–4.3%), with no change in women or overall. There was an annual decrease of 1.1% in odds for ANOs among hospitalised overall (95% CI: 0.1–2.1%) and of 1.4% in men (95% CI: 0.0–2.7%), while no change was observed in women. LOS decreased annually by 2.5% (95% CI: 2.1–2.9%). The incidence of TBI-related deaths was 70/100,000 person-years with an estimated annual increase of 1.6% in women (95% CI: 0.2–2.9%), but no change in men or overall. Mean ages of TBI-related admissions and deaths increased (P &lt; 0.001).

Interpretation
the incidence rate of geriatric TBI-related hospitalisations increased, especially in women, but LOS and the rate of ANOs among hospitalised decreased. The overall TBI-related mortality remained stable, and IHM decreased in men, while in women, the overall mortality increased and IHM remained stable. However, the overall incidence rates of TBI-related hospitalisations and deaths and the number of cases of IHM were still higher in men.
Statin-induced autoimmune necrotizing myopathy with pharyngeal muscles involvement
Authors: Mirlesse Nicolas , Egervari Kristof , Bornand Aurélie , Lecluse Julien , Lobrinus Johannes A , Scheffler Max , Serratrice Christine , Prendki Virginie , Cuvelier Clémence 
Published: February 2020

Abstract
Statins are widely prescribed in the treatment of hypercholesterolemia. While their efficacy in the secondary prevention of vascular events is proven, their safety profile in older patients with multiple co-morbidities and polypharmacy remains questionable. Although rare, antihydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy is a severe adverse effect of statins, manifesting as myalgias, proximal muscle weakness, muscle cell necrosis and rhabdomyolysis. We report an uncommon case of an autopsy-proven anti-HMGCR necrotising myopathy predominately affecting pharyngeal muscles in an older patient, leading to dysphagia, pneumonia and death within 3 weeks from onset. Clinicians should screen for dysphagia in any patient with suspected anti-HMGCR myopathy, order an anti-HMGCR antibody titre and consider prompt immunosupressive therapy.
25 A Pilot Implementation of Providing Enhanced Support to Care Homes within A Primary Care Network
Authors: Didehvar R , Ehtheshamirad G , Batty G , Sage S , Mullins S , Thomas C 
Published: February 2020

Abstract

Introduction
People living with severe frailty in care homes are vulnerable to frequent non-elective hospital attendances. However provision of enhanced healthcare support to care home residents can reduce this risk and increase quality of life for residents.1 The framework for enhanced health in care homes (EHCH) summarises best practice in this area and provides guidance for implementing services.2

Methods
This study was a pilot implementation of the EHCH framework based on a Primary Care and Specialist Frailty Multidisciplinary Team (MDT) and delivered on a Primary Care Network (PCN) footprint. The MDT targeted five care homes in a PCN area with historically high levels of non-elective attendances. The model of care was based on the principle of anticipatory care planning, training and support for care home staff to understand and implement plans.

Results
Over the pilot period of 9 months, non-elective attendances from the 5 homes reduced by 27% compared to the previous year, which was a significant reduction (p&lt;0.042). There was variation between the homes in the reduction in non-elective attendances with the greatest impact seen in the homes that had the highest level of attendance at training and engagement in the care planning process. Feedback received from the care home staff indicated that they felt more confident to refer to the care plans and had alternative options to calling 999. A quality audit of the care plans completed as part of the pilot revealed a number of additional training needs for clinicians completing the plans to ensure consistency of recoding. This training was delivered following the pilot period.

Conclusions
The pilot demonstrated that the EHCH framework could be successfully implemented on a PCN footprint. Analysis shows this implementation coincided with a reduction in non-elective attendances from the targeted homes. Further analysis is required to compare the impact in different homes and to understand contributing factors. The pilot implementation provides helpful information to inform PCN development.

References
1. Lloyd T, Wolters A and Steveton A (2014) The impact of providing enhanced support for care home residents in Rushcliffe: Health Foundation consideration of findings from the Improvement Analytics Unit. The Health Foundation.
2. NHS England (2016) The framework for enhanced health in care homes.
28 Can Comprehensive Geriatric Assessment be Achieved in the Emergency Department?
Authors: Cheng J , Ho C , Honney K , Wells M , Wise W , Ferguson N , Bailey S , May H , Burridge R 
Published: February 2020

Abstract

Background
Our National Health Service is facing unprecedented challenges to accommodate our frailer healthcare users. The gold standard tool for the identification and management of frailty is the Comprehensive Geriatric Assessment (CGA) and has been shown to lead to better outcomes in terms of morbidity and mortality.

Introduction
With a largely elderly demographic profile in the East of England, the Norfolk and Norwich University Hospital opened the first Older People’s Emergency Department (OPED) in the UK in 2017. This work reviews the effectiveness of a geriatrician-led CGA in a dedicated OPED, which operates during daylight hours, compared to usual care in Accident & Emergency (A&E).

Methods
99 patients assessed in OPED and 99 patients assessed overnight in A&E during February 2019 were included in this retrospective study. Electronic case notes for each patient were reviewed by the authors and results were expressed as percentages.

Results
OPED outperformed A&E in all components of the CGA; strongest areas included assessing for pain, falls risk and activities of daily living. Both departments performed well in reviewing medications and assessing for safeguarding concerns. Areas for improvement include assessing for mood disorders, sensory impairment, discussing Do Not Attempt Cardiopulmonary Resuscitation status, and end of life care plans. The average length of stay of OPED patients was only 7.3 days compared to 8.7 days in A&E, and 89% of OPED patients were discharged back to their usual residences compared to 87% in A&E.

Conclusions
The improved CGA process in OPED has led to better outcomes, notably through a reduction in the average length of inpatient stay. Nevertheless, certain components of the CGA still require improvement. Further examination is needed to assess long-term mortality to support the use of CGA in the emergency setting.
69 What Health Outcomes Matter to Frail Older People?
Authors: Tipping K S 
Published: February 2020

Abstract

Introduction
The purpose of this project was to explore what health outcomes matter to frail older people. This would provide information that would be of use to both providers and payers of health care services to align their priorities in line with these. Frailty is an important and relevant topic in healthcare. In England 5% of people aged 60-69 have frailty. This rises to 65% in people aged over 90. There are 1.8 million people aged over 60 and 0.8 million people aged over 80 living with frailty. (English Longitudinal Study of Ageing (2016)). This number is due to increase.
The aims of this research were: To review the literature on health outcomes in older people including frail older people.To conduct a focus group interview with frail older people to ascertain their views on health outcomes.To disseminate and share the reviews and study findings via presentations and publications.

Ethics
Ethical approval was granted by the University of Liverpool’s Health and Life Sciences Research Ethics Committee (application number 4163).

Methods
A systematic review of the literature was undertaken. Thereafter a focus group interview was held with six frail older people. The participants were aged 65 years and over and had mild to moderate frailty using the Clinical Frailty Scale. The interview recording was transcribed, and common themes identified and analysed.

Results
Eight themes were identified from the focus group: - Trust in medical professionalsVulnerability of being an older person in hospitalPolypharmacy and wastage of medicationDischarge Planning & Co-Ordination of Care at HomeTaking responsibility for your own healthNomenclatureAutonomyFalls

Conclusion
This study has identified themes that can be utilised to raise awareness among health care professionals on what matters to frail older people. The study findings will hopefully provide an opportunity for meaningful discussions around what is needed to better meet these desired health outcomes.

References
1. Akpan A, Roberts C, Bandeen-Roche K, Batty B, Bausewein C, Bell D, et al. Standard set of health outcome measures for older persons. BMC Geriatr 2018;18(1):36.
2. Naik AD, Dindo LN, Van Liew JR, Hundt NE, Vo L, Hernandez-Bigos K, et al. Development of a Clinically Feasible Process for Identifying Individual Health Priorities. Journal of the American Geriatrics Society 2018;66(10):1872–9.
Histopathological Features of Tissue Alterations Induced by Cryolipolysis on Human Adipose Tissue
Authors: Pugliese Domenico , Melfa Fabrizio , Guarino Enrico , Cascardi Eliano , Maggi Michela , Ferrari Eleana , Maiorano Eugenio 
Published: February 2020

Abstract

Background
Adipose tissue cooling, under controlled conditions, induces physical effects on subcutaneous tissue called cryolipolysis (CLL), which has been proposed as a method to reduce noninvasively the amount of adipose tissue. Although CLL has been widely utilized in clinical practice and many favorable results have been reported in clinical studies, very few published studies have dealt with the effects of such therapies on human adipose tissue.

Objectives
The aim of this study was to evaluate, through histopathological examination, the in vivo effects of CLL on human adipose tissue.

Methods
Six patients to be submitted to abdominoplasty were enrolled in the study. Samples were taken from the surgical patch, respectively, 15 days (2 pts), 45 days (2 pts), and 60 days (2 pts) after a single standard session of CLL. Control samples were derived from the nontreated areas of the surgical patch.

Results
Disruption of the adipocytic membranes was evident in all treated areas, with a reduction of cell dissolution in the 60-day samples. Focal dissolution and homogenization of the collagen fibers was evident, resulting in the dissolution of the interlobular fibrous septa. A mild inflammatory response was observed in the 15- and 45-day samples. Neocapillarizzation was observed in the 45- and 60-day samples.

Conclusions
The lesions demonstrated in adipocytes confirm the theoretical premises of a usefulness of CLL in the treatment of localized adiposis. The alterations in the connective stroma could lead to a structural reorganization and consequently to the in vivo external appearance of the treated areas.

Level of Evidence: 5