bluuebunny/crossref_metadata_2025_split huggingface dataset:
Litigation claims following laparoscopic and open inguinal hernia repairs
Authors: Varley R. , Lo C. , Alkhaffaf B. 
Published: March 2020

Abstract
Purpose
Groin hernia repair is the most frequently performed general surgical operation in the UK. Complications from laparoscopic and open repair are well recognised; however, potential differences are yet to be considered in relation to litigation.

Methods
Administrative data were obtained and analysed from the NHS Litigation Authority for inguinal hernia-related claims from 1995 to 2016. Claims identified as using an open or laparoscopic approach were compared.

Results
880 claims were made, 760 had been settled. 88 laparoscopic and 241 open procedures were identified; 65% laparoscopic and 63% open hernia claims were found to be in favour of the claimant. Payouts totalled to 4.1GBP/4.8EUR/5.3USD million and 9.4GBP/11.0EUR/12.1USD million for laparoscopic (mean 82,824GBP/96,579EUR/106,453USD) and open (mean 66,796GBP/77,892EUR/85,852USD) approaches, respectively. The most common reasons for claim initiation were visceral/vascular injury (54%) in the laparoscopic group, and testicular complications or chronic pain (35%) in the open group. Additional procedures were necessary for 48% and 44% of laparoscopic and open claims, respectively. The highest average payouts were associated with visceral injury, (laparoscopic 116,482GBP/135,820EUR/149,715USD; open 199,103GBP/232,246EUR/255,905USD) and vascular injury (laparoscopic 88,624GBP/103,369EUR/113,892USD; open 64,460GBP/75,163EUR/82,870USD). Additional procedures resulted in an average payout of 93,352GBP/108,917EUR/120,008USD (laparoscopic) and 60,408GBP/70,506EUR/77,657USD (open). The most common additional procedures were corrective visceral/vascular repairs, orchidectomy and recurrent hernia repair.

Conclusions
The rate of litigation for clinical negligence in inguinal hernia surgery in the UK is increasing. Whilst there has been a recent increase in laparoscopic hernia repair claims, the volume and burden of claims related to open procedures remain greater.
A retrospective analysis of budget impact models submitted to the National Centre for Pharmacoeconomics in Ireland
Authors: Lamrock Felicity , McCullagh Laura , Tilson Lesley , Barry Michael 
Published: March 2020

Abstract
Background
The National Centre for Pharmacoeconomics (NCPE) is a National HTA Agency in Ireland responsible for assessment of comparative clinical effectiveness, cost-effectiveness and potential budget impact of drugs on behalf of the Health Service Executive. This research aims to assess if the budget impact models submitted to the NCPE have accurate predicted utilisation, assess if the models are consistent in the parameters included, and determine if probabilistic sensitivity analyses would aid the characterization of uncertainty.

Methods
A retrospective analysis of budget impact models that had been submitted (January 2010–December 2017 inclusive) to the NCPE was performed. The input parameters in the budget impact model were recorded. For each drug, annual realised utilisation was compared with what had been predicted by the respective budget impact model. A probabilistic sensitivity analysis was also performed on each model.

Results
A total of 12 models were included; each model pertained to one drug for one indication. Of the 12 models, six underpredicted and six overpredicted the annual realised utilisation. There were a range of different parameters included in each of the budget impact models. A probabilistic sensitivity analysis did not improve the characterization of uncertainty.

Conclusion
This research has demonstrated that budget impact models submitted to a national HTA agency have limited accuracy in predicting realised utilisation, and there is inconsistency among the parameters included. An electronic budget impact template for applicants has been developed, as a more systematic approach, for their submissions to the NCPE.
Mechanisms of Motivational Interviewing for Antiretroviral Medication Adherence in People with HIV
Authors: Hogan Ailbhe , Catley Delwyn , Goggin Kathy , Evangeli Michael 
Published: March 2020

AbstractAntiretroviral therapy (ART) for HIV requires strict regimen adherence. Motivational interviewing (MI) can improve ART adherence. MI process studies have rarely focussed on ART adherence. Such studies may facilitate MI modifications to improve outcomes. This study employed a single group pre and post-test design with 62 adults with HIV (16 female; mean age 40 years). Therapist use of MI-consistent (MICO) methods, MI spirit, and client change and sustain talk were coded from an MI session. Relationships were assessed with ART schedule adherence. MICO methods positively correlated with change and sustain talk and were negatively associated with proportion of change talk. No variables were associated with ART adherence change. Mediation analysis did not support the MI model of change. This may be due to the fact that ART adherence is determined by both motivational and non-motivational factors. It may also be that bidirectional relationships exist between therapist and client speech.
State-of-the-art and challenges of railway and road vehicle dynamics with multibody dynamics approaches
Authors: Bruni S. , Meijaard J. P. , Rill G. , Schwab A. L. 
Published: March 2020

AbstractA review of the current use of multibody dynamics methods in the analysis of the dynamics of vehicles is given. Railway vehicle dynamics as well as road vehicle dynamics are considered, where for the latter the dynamics of cars and trucks and the dynamics of single-track vehicles, in particular motorcycles and bicycles, are reviewed. Commonalities and differences are shown, and open questions and challenges are given as directions for further research in this field.
Intersectionality: A pathway towards inclusive education?
Authors: Bešić Edvina 
Published: March 2020

AbstractThis article aligns with recent international approaches to inclusive education and argues for a broadened understanding of the term, specifically in the context of Austria, which currently focuses only on children with disabilities. The article not only sets out the thesis of intersectionality, but calls for the adoption of an intersectional lens in inclusive education in order to identify the interaction of multiple factors that lead to discriminatory processes in schools towards different student groups. Inclusive education means opening access to a wide range of educational and social opportunities for all children, not only those with disabilities or identified special education needs. The current system, in which children possess one identity marker, does not provide the support children need. Furthermore, it also reinforces inequalities not only within the education system, but also within society at large.
Image quality of a portable X-ray device (Nomad Pro 2) compared to a wall-mounted device in intraoral radiography
Authors: Nitschke Julia , Schorn Lara , Holtmann Henrik , Zeller Uwe , Handschel Jörg , Sonntag David , Lommen Julian 
Published: March 2020

Abstract
Objectives
The aim of this study was to determine whether a handheld (HH) X-ray device (Nomad Pro 2) is capable of producing equivalent or even superior X-ray image quality in comparison to a wall-mounted (WM) dental X-ray unit (Heliodent Plus) on the basis of objectifiable image quality parameters.

Methods
Anatomical, radiological and biological dental X-ray image quality parameters of a handheld dental X-ray device (Nomad Pro 2, Kavo Kerr, Biberach, Germany) were compared to a standard wall-mounted dental X-ray unit (Heliodent Plus, Sirona Dental Systems, Bensheim, Germany) using a maxillofacial phantom. In addition, the effect of different operators (dentists, dental students, dental assistants) on the dental X-ray image quality was measured.

Results
HH and WM devices showed comparable image quality for anterior teeth, premolars, molars and bitewing images. During the two-month investigational period, the radiation exposure level for the operator of the Nomad Pro 2 was 0.1 mSv for 203 images. Dentists as the highest trained personnel enrolled in the study achieved better image quality with the Nomad Pro 2 as compared to dental students and dental assistants, especially in the molar region.

Conclusions
A HH device delivers a comparable image quality to a WM device. In addition, there seem to be short learning curves with regard to image acquisition when using a handheld device, which is further minimised by the previous training of the operating personnel. HH dental X-ray devices, such as the Nomad Pro 2 are a promising adjunct for dental radiology in cases where WM units are of limited practicability.
A Robust Effect Size Index
Authors: Vandekar Simon , Tao Ran , Blume Jeffrey 
Published: March 2020

Effect size indices are useful tools in study design and reporting because they are unitless measures of association strength that do not depend on sample size. Existing effect size indices are developed for particular parametric models or population parameters. Here, we propose a robust effect size index based on M-estimators. This approach yields an index that is very generalizable because it is unitless across a wide range of models. We demonstrate that the new index is a function of Cohen’s d, R2\documentclass[12pt]{minimal}
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\begin{document}$$R^2$$\end{document}, and standardized log odds ratio when each of the parametric models is correctly specified. We show that existing effect size estimators are biased when the parametric models are incorrect (e.g., under unknown heteroskedasticity). We provide simple formulas to compute power and sample size and use simulations to assess the bias and standard error of the effect size estimator in finite samples. Because the new index is invariant across models, it has the potential to make communication and comprehension of effect size uniform across the behavioral sciences.
Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients
Authors: Cook Aaron M. , Morgan Jones G. , Hawryluk Gregory W. J. , Mailloux Patrick , McLaughlin Diane , Papangelou Alexander , Samuel Sophie , Tokumaru Sheri , Venkatasubramanian Chitra , Zacko Christopher , Zimmermann Lara L. , Hirsch Karen , Shutter Lori 
Published: March 2020

Background
Acute treatment of cerebral edema and elevated intracranial pressure is a common issue in patients with neurological injury. Practical recommendations regarding selection and monitoring of therapies for initial management of cerebral edema for optimal efficacy and safety are generally lacking. This guideline evaluates the role of hyperosmolar agents (mannitol, HTS), corticosteroids, and selected non-pharmacologic therapies in the acute treatment of cerebral edema. Clinicians must be able to select appropriate therapies for initial cerebral edema management based on available evidence while balancing efficacy and safety.

Methods
The Neurocritical Care Society recruited experts in neurocritical care, nursing, and pharmacy to create a panel in 2017. The group generated 16 clinical questions related to initial management of cerebral edema in various neurological insults using the PICO format. A research librarian executed a comprehensive literature search through July 2018. The panel screened the identified articles for inclusion related to each specific PICO question and abstracted necessary information for pertinent publications. The panel used GRADE methodology to categorize the quality of evidence as high, moderate, low, or very low based on their confidence that the findings of each publication approximate the true effect of the therapy.

Results
The panel generated recommendations regarding initial management of cerebral edema in neurocritical care patients with subarachnoid hemorrhage, traumatic brain injury, acute ischemic stroke, intracerebral hemorrhage, bacterial meningitis, and hepatic encephalopathy.

Conclusion
The available evidence suggests hyperosmolar therapy may be helpful in reducing ICP elevations or cerebral edema in patients with SAH, TBI, AIS, ICH, and HE, although neurological outcomes do not appear to be affected. Corticosteroids appear to be helpful in reducing cerebral edema in patients with bacterial meningitis, but not ICH. Differences in therapeutic response and safety may exist between HTS and mannitol. The use of these agents in these critical clinical situations merits close monitoring for adverse effects. There is a dire need for high-quality research to better inform clinicians of the best options for individualized care of patients with cerebral edema.
Movement sonification expectancy model: leveraging musical expectancy theory to create movement-altering sonifications
Authors: Newbold Joseph , Gold Nicolas E. , Bianchi-Berthouze Nadia 
Published: March 2020

AbstractWhen designing movement sonifications, their effect on people’s movement must be considered. Recent work has shown how real-time sonification can be designed to alter the way people move. However, the mechanisms through which these sonifications alter people’s expectations of their movement is not well explained. This is especially important when considering musical sonifications, to which people bring their own associations and musical expectation, and which can, in turn, alter their perception of the sonification. This paper presents a Movement Expectation Sonification Model, based on theories of motor-feedback and expectation, to explore how musical sonification can impact the way people perceive their movement. Secondly, we present a study that validates the predictions of this model by exploring how harmonic stability within sonification interacts with contextual cues in the environment to impact movement behaviour and perceptions. We show how musical expectancy can be built to either reward or encourage movement, and how such an effect is mediated through the presence of additional cues. This model offers a way for sonification designers to create movement sonifications that not only inform movement but can be used to encourage progress and reward successes.
3-Year follow-up of a single magnetically controlled growing rod with contralateral gliding system and apical control for early onset scoliosis
Authors: Wijdicks Sebastiaan P. J. , Skov Simon Toftgaard , Li Haisheng , Castelein René M. , Kruyt Moyo C. , Bünger Cody 
Published: March 2020

Abstract
Study design
Two-center retrospective cohort study.

Objective
The aim of this study is to investigate the clinical effectiveness and safety of the MCGR hybrid in terms of spinal growth, 3D correction, balance, and complications.

Summary of background data
The magnetic-controlled growing-rod (MCGR) growth instrumentation method has gained popularity for early onset scoliosis (EOS) treatment in the past years due to the non-invasiveness of the subsequent interval elongation procedures. To improve 3D correction and reduce the costs, we combined a single concave MCGR with a sliding rod on the convex side to control the apex.

Methods
A retrospective cohort study of 18 EOS children with an average 3-year follow-up (range 2.0–3.7) from two European spine centers treated with the single MCGR hybrid concept; 14 primary and 4 conversion cases. The primary and conversion cases were both evaluated preoperatively, postoperatively, 1 year, 2 years, and last follow-up.

Results
Mean age was 9.9 (SD ± 2.9 years). The average frontal Cobb angle was reduced from mean 65° to 30° postoperatively, and had increased to 37° at latest follow-up. Rotation of the apical vertebra improved from mean 27° to 20° postoperatively which was partially lost to 23°. Kyphosis and lordosis both increased by an average of 5° during the time of follow-up. Spinal balance was improved. The post-implantation T1–S1 spine growth rate averaged 10 mm/year at last follow-up. There were 13 implant-related complications in 6 out of 18 patients. No screw pull-outs and nor surgical site infections were registered.

Conclusions
This is the first medium-term results of a single MCGR hybrid construct. Maintenance of correction and growth are reasonable, and the complication rate is relatively low as compared to bilateral MCGR application.

Level of evidence
III.
Household wealth proxies for socio-economic inequality policy studies in China
Authors: Lam Jacqueline C. K. , Han Yang , Bai Ruiqiao , Li Victor O. K. , Leong Jeff , Maji Kamal J. 
Published: March 2020

AbstractIn China, one percent of the richest population holds more than one-third of the wealth, while the poorest 25% shares no more than two percent of the total. The country’s rapid economic development has resulted in increasing socio-economic disparities, and a rapidly deteriorating environment. This puts the Chinese citizens, especially the most vulnerable and deprived socio-economic status (SES) groups, at high risks of environmental inequality (EI). In most SES-based EI studies conducted in China, household wealth has often been overlooked, though it potentially serves a good economic indicator to capture the socio-economic effect of environmental change in China. Nevertheless, existing SES databases in China are of low spatial resolution and are insufficient to support fine-grained EI studies at the intra-city level in China. The core research challenge is to develop a representative household wealth proxy in high-spatial resolution for China. This study highlights the research gaps and proposes a new household wealth proxy, which integrates both fine-grained data/features such as daytime satellite imagery and easily accessible wealth indicators such as house prices. We also capitalize on everyday economic activity data retrieved from personal mobile phones and online transaction/social platforms in the composition of our wealth proxy to achieve a higher accuracy in estimating household wealth at fine-grained resolution via machine learning. Finally, we summarize the challenges in improving both the quality and the availability of Chinese socio-economic datasets, while protecting personal privacy and information security during the data collection process for household wealth proxy development in China.
A Randomized Trial of Instructor-Led Training Versus Video Lesson in Training Health Care Providers in Proper Donning and Doffing of Personal Protective Equipment
Authors: Christensen Liva , Rasmussen Charlotte Schang , Benfield Thomas , Franc Jeffrey Michael 
Published: March 2020

ABSTRACTObjective:This study compared live instructor-led training with video-based instruction in personal protective equipment (PPE) donning and doffing. It assessed the difference in performance between (1) attending 1 instructor-led training session in donning and doffing PPE at 1 month prior to assessment, and (2) watching training videos for 1 month.Methods:This randomized controlled trial pilot study divided 21 medical students and junior doctors into 2 groups. Control group participants attended 1 instructor-led training session. Video group participants watched training videos demonstrating the same procedures, which they could freely watch again at home. After 1 month, a doctor performed a blind evaluation of performance using checklists.Results:Nineteen participants were assessed after 1 month. The mean donning score was 84.8/100 for the instructor-led group and 88/100 for the video group; mean effect size was 3.2 (95% CI: -7.5 to 9.5). The mean doffing score was 79.1/100 for the instructor-led group and 73.9/100 for the video group; mean effect size was 5.2 (95% CI: -7.6 to 18).Conclusion:Our study found no significant difference in donning and doffing scores between instructor-led and video lessons. Video training could be a fast and resource-efficient method of training in PPE donning and doffing in responding to the COVID-19 pandemic.
TheKaččāand thePakkā: Disenchanting the Film Event in Pakistan
Authors: Cooper Timothy P. A. 
Published: March 2020

AbstractFor many city dwellers in Pakistan the distant memory of outdoor cinemas in their ancestral villages rekindles the thrill of first contact with film exhibition. This paper considers attempts made in colonial British India and postcolonial Pakistan to understand, wield, and benefit from the staging of such memorable and affective filmic events. In its cultivation of “cinema-minded” subjects, the British Empire commissioned studies of audiences and their reactions to film exhibition in hopes of managing the unruly morality and materiality of the cinematic apparatus. After Partition and the creation of the Dominion of Pakistan, similar studies continued, evincing a residual strategy of elicited contact. The elicitation of film contact aimed at the exertion and commandment of the event of film exhibition for the purposes of knowing their constituent subjects at a moment of malleability. Yet the Empire's struggle with the perceived problems of “Muslim tastes” and audience members’ ambivalence over rural screenings in post-Partition Pakistan calls for a reconsideration of the efficacy of these tactics. I argue that what complicated these encounters are affective responses that questioned the address, permissibility, and efficacy of film exhibition. In these tactics of elucidation, disenchantment, and denial, ruptures are refused and the new is dismissed as inoperable, incompatible, or impermissible.
Brutalism and the People: Architectural Articulations of National Developmentalism in Mid-Twentieth-Century São Paulo
Authors: Bortoluci José H. 
Published: March 2020

AbstractThis article examines the question of how architects in São Paulo during the 1950s and 1960s addressed the political nature of their work, and more specifically the connections between their practice and the lives and politics of the urban poor in the context of a rapidly expanding metropolis of the Global South. More specifically, it assesses how they elaborated strategies to articulate the semiotic and material practices of Brutalism and the political repertoire of national developmentalism, initially in its democratic and later in its authoritarian form. The article argues that these architects deployed two semio-material strategies to operationalize the articulation between that political repertoire and the field of architecture: metaphorical indexicality and the impetus for the industrialization of construction. The image of the urban poor reinforced by that political repertoire was marked by a severe distance from their empirical life experiences, which deeply affected the practices of design and construction that progressive architects advanced.
Home language environment and children's second language acquisition: the special status of input from older siblings
Authors: SORENSON DUNCAN Tamara , PARADIS Johanne 
Published: March 2020

AbstractPrevious research suggests that increased second language (L2) input at home may not support L2 acquisition in children from migrant backgrounds. In drawing this conclusion, existing work has largely aggregated across family members. This study contrasts the effect of L2 input from older siblings with that from mothers. Participants were 113 child L2 learners of English (mean age = 5;10 [range 4;10–7;2]; mean exposure to L2 in school = 16.7 months [range 2–48 months]). All children had at least one older sibling. Using hierarchical linear regression modelling with controls for age, non-verbal reasoning and phonological short-term memory, we found that greater L2 input from siblings – but not mothers – was associated with stronger L2 abilities in narrative macrostructure, inflectional morphology, and vocabulary. Increased cumulative exposure to the L2 at school and greater maternal L2 fluency were also positively related to children's L2 inflectional morphology and vocabulary scores.