bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trastuzumab-induced thrombocytopenia after eight cycles of trastuzumab treatment
Authors: Zhou Qiong , Dong Jie , Jiang Xiaodong , Pan Yueyin , Han Xinghua 
Published: July 2020

Abstract
Trastuzumab, a humanized monoclonal antibody derived from recombinant DNA, is used in patients with breast cancer with HER2 gene amplification. The survival benefit from trastuzumab has been well established in patients with early and metastatic breast cancer who had over expression of HER2. We reported a case of severe thrombocytopenia after eight cycles of trastuzumab treatment for breast cancer. Before the 9th trastuzumab treatment, the patient’s platelet decreased to 48 × 109/L. Recombinant human thrombopoietin was used, and the platelet level increased to normal level. Before the 10th treatment, the platelet count of the patient was 99 × 109/L. However, during the 10th and 11th trastuzumab treatment, the platelet count decreased to 5 × 109/L in 24 h. After treatment with TPO and corticosteroids, the platelet levels increased to the normal level in 7 days. Trastuzumab-induced thrombocytopenia is rare but still occurred even after 8 cycles of trastuzumab treatment.
Medical Confidentiality after Patient Death in Selected Civil and Common Law Systems
Authors: Bagan-Kurluta Katarzyna , Drozdowska Urszula 
Published: July 2020

Abstract
The paper presents problems related to medical confidentiality after the patient’s death. The reasons for the waiver of this secret need to be considered. To this end, the authors analysed Polish regulations of medical law and then compared them to selected European regulations: French and English law. The inspiration for describing these two legal orders were two media-highlighted cases of the publication of medical diaries after the deaths of people holding the highest state offices: Lord Moran and Dr. Claude Gubler. The first doctor published his memoirs concerning the state of health of the English statesman of World War II – Winston Churchill, while the second published his memoirs after the death of the French President – François Mitterrand. The authors describe the reaction of the law to these breaches of secrecy after the deaths of the patients, and confront them with the current regulations. The whole is crowned with conclusions resulting from the comparison of Polish, French and English law. The paper uses the dogmatic-legal and comparative methods.
Medical Secrets vs. GDPR
Authors: Zaremba Joanna 
Published: July 2020

Abstract
The work of the doctor and other health professionals is closely related with access to information on the health of patients. The disclosure of such information leads to many consequences. It also violates the privacy of the patient.The obligation to maintain medical confidentiality is regulated by law, and is based on the ethics of the medical profession. Regulations that regulate the principles of medical confidentiality are contained in the Act of 5 December 1996 on the professions of doctor and dentist. Information on the health of patients is covered by special confidentiality, because these are specific data requiring confidentiality.
The information that relates to the patient and is obtained during medical work, including data on the patient’s life or property, are medical secrets. There are a few exceptions for which the doctor may be released from medical confidentiality. These include consent of the patient him/herself, consent resulting from the act and removal of medical confidentiality in the case of danger to the patient or other persons, and with the consent of public authorities.
It is very important to consider the protection of personal data, including sensitive data, which includes medical data contained in the provisions of the GDPR. This regulation comprehensively regulates the issues of personal data protection, also including medical confidentiality, by prohibiting the processing of patient data by medical entities without authorization.
The purpose of this article was to analyze the correlation between regulations relating to medical confidentiality and the provisions of the GDPR, which are new tools for the protection of personal data. The article discusses issues regarding the subject scope of medical confidentiality, exemption from its behaviour, and liability for possible violations.
An Experimental Study on Effect of Concrete Performance in Addition of GGBS and Partial Replacement of Cement by Glass Fiber
Authors: Singh Pratap , Jaldhari Ramanuj 
Published: July 2020

The aim of this study is to evaluate the performance of M35 grade of concrete in addition of Ground-granulated blast-furnace slag and partial replacement of cement by glass fiber. Ground-granulated blast-furnace slag is pozzolanic materials that can be utilized to produce highly durable concrete composites. In this study Ground-granulated blast-furnace slag has been used to OPC which varies from 5% to 10% at interval of 2.5% by total weight of OPC and similarly partial replacement of OPC (43 grade) by glass fiber which varies from 0% to 0.4% at interval of 0.1% by total weight of OPC. All mixes (trial mix, control mix and variation mix) were prepared for M35 grade of concrete. This study investigates the performance of concrete mixture in terms of slump, compressive strength for 7days and 28 days, Flexural strength of beam 28 days and Splitting tensile strength of Cylinder for 28 days respectively.
Vine Copula-Based Dependence Modeling of Multivariate Ground-Motion Intensity Measures and the Impact on Probabilistic Seismic Slope Displacement Hazard Analysis
Authors: Wang Mao-Xin , Huang Duruo , Wang Gang , Du Wenqi , Li Dian-Qing 
Published: July 2020

ABSTRACT
Multivariate normality of logarithmic intensity measures (IMs) is conventionally assumed in earthquake engineering applications. This article introduces a vine copula approach as a useful tool for multivariate modeling of IMs. This approach provides a flexible way to decompose a joint distribution into individual marginal distributions and multiple dependences characterized by a cascade of bivariate copulas (pair-copulas), whereas the conventional multivariate normality can be considered as a special case of the vine copula model. Based on the Next Generation Attenuation-West1 database and various combinations of ground-motion prediction equations (GMPEs), the optimal dependence structures among peak ground acceleration, peak ground velocity, and Arias intensity, as well as that for spectral accelerations at four periods, are identified. The joint normality assumption for the two vector sets of logarithmic IMs is examined from the perspective of copula theory. The results illustrate that the normality assumption is generally adequate for bivariate IMs but may not be optimal for multivariate IMs. Using the same set of GMPEs (developed by the same researchers) may improve the joint normality for logarithmic IMs. Furthermore, the impact of dependence structures among IMs on probabilistic seismic slope displacement hazard analysis is explored. The results indicate that using the same Pearson correlation coefficients but different dependence structures for IMs produces different hazard results and this difference is generally enlarged with increasing hazard levels. As hazard difference from different dependence structures is generally not significant, the multivariate normality distribution for logarithmic IMs is judged to be an acceptable assumption in engineering practice. Alternatively, engineers may make a choice between the joint normal distribution and the vine copula tool depending on the specific situation because of the better generality of the latter.
Magnetic Field Variations in Alaska: Recording Space Weather Events on Seismic Stations in Alaska
Authors: Ringler Adam T. , Anthony Robert E. , Wilson David C. , Claycomb Abram C. , Spritzer John 
Published: July 2020

ABSTRACTSeismometers are highly sensitive instruments to not only ground motion but also many other nonseismic noise sources (e.g., temperature, pressure, and magnetic field variations). We show that the Alaska component of the Transportable Array is particularly susceptible to recording magnetic storms and other space weather events because the sensors used in this network are unshielded and magnetic flux variations are stronger at higher latitudes. We also show that vertical-component seismic records across Alaska are directly recording magnetic field variations between 40 and 800 s period as opposed to actual ground motion during geomagnetic events with sensitivities ranging from 0.004 to 0.48  (m/s2)/T. These sensitivities were found on a day where the root mean square variation in the magnetic field was 225 nT. Using a method developed by Forbriger (2007, his section 3.1), we show that improving vertical seismic resolution of an unshielded sensor by as much as 10 dB in the 100–400 s period band using magnetic data from a collocated three-component magnetometer is possible. However, due to large spatial variations in Earth’s magnetic field, this methodology becomes increasingly ineffective as the distance between the seismometer and magnetometer increases (no more than 200 km separation). A potential solution to this issue may be to incorporate relatively low-cost magnetometers as an additional environmental data stream at high-latitude seismic stations. We demonstrate that the Bartington Mag-690 sensors currently deployed at Global Seismographic Network sites are not only acceptable for performing corrections to seismic data, but are also capable of recording many magnetic field signals with similar signal-to-noise ratios, in the 20–1000 s period band, as the observatory grade magnetometers operated by the U.S. Geological Survey Geomagnetism Program. This approach would densify magnetic field observations and could also contribute to space weather monitoring by supplementing highly calibrated magnetometers with additional sensors.
The Relationship of Budget Emphasis on the Tendency to Create Budgetary Slack
Authors: . Sulastri , Tri Wardani Maya 
Published: July 2020

This study aims to find empirical evidence to support the notion that there is a connection between the budget emphasis and the potential budgetary slack. In this study, there were 65 respondents (out of a potential pool of 872 employees of the regional water supplier for Malang city). Of the 65 questionnaires distributed, 57 were returned fully completed. The data collected was then analyzed using the Product Statistics and Services Solution (SPSS) application program. This study uses a simple linear regression analysis technique to measure the impact of the budget emphasis variable to budgetary slack. The results show that the budget emphasis produced a positive effect on the incidence of budgetary slack, however when the budget emphasis is too tight it can cause aberrant behavior in subordinates owing working pressures to achieve set targets.
Keywords: Budget Emphasis, Budgetary Slack
INTEGRATED PROGRAMS (IP) PADA ROGRAM KEMITRAAN MASYARAKAT (PKM) DI UKM BUNDA SUKOLILO BARU, KECAMATAN BULAK, SURABAYA
Authors: Widihartanti Theresia , Sulestiani Aniek , Agustin Titiek Indira , Wijaya Nirmalasari Idha , Prayogi Urip 
Published: July 2020

Sukolilo Baru is one of the tourist destination centers focused on selling dried and semi-finished fish products so that it is much sought after by tourists. However, the arrangement of processing rooms is far from adequate standards. Integrated Programs (IP) in the community service include (a) Tutorial on the cultivation of eggplant and sea cucumbers; (b) Tutorial on GMP; (c) Making crackers drying tools as appropriate technology. Drying crackers made from seafood still relies on sunlight and still uses space on the edges of the road. One of the tools needed is a weatherproof, eggplant and sea cucumber drying tool. This has become the foundation of the Faculty of Engineering and Marine Sciences of UHT to implement knowledge in its engineering field to make an effective drying tool by utilizing the limited land, which is above the storeroom of dried eggplant and sea cucumbers. By using the glass drying device, the drying time will be 3 days from 7-10 days, so that the effectiveness of the drying tool has been proven; (d) Arrangement of PIRT as the legality of the product for consumption. Thus, the Integrated Programs (IP) implemented by the FTIK community service team succeeded in improving the welfare of Sukolilo Baru, Surabaya.abstrakKelurahan Sukolilo Baru merupakan salah satu pusat tujuan wisata fokus pada penjualan produk ikan kering dan setengah jadi sehingga banyak diminati oleh wisatawan. Namun, penataan ruang pengolahan jauh dari standar memadai. Integrated Programs (IP) pada pengabdian kepada masyarakat tersebut meliputi (a) Tutorial tentang budidaya terung dan teripang; (b) Tutorial tentang GMP; (c) Pembuatan alat penjemur kerupuk sebagai teknologi tepat guna. Penjemuran bahan kerupuk berbahan baku hasil laut masih mengandalkan sinar matahari dan masih memakai ruang di pinggir-pinggir jalan. Salah satu alat yang dibutuhkan adalah alat penjemuran terung dan teripang basah yang tahan cuaca. Hal inilah yang menjadi landasan Fakultas Teknik dan Ilmu Kelautan UHT untuk mengimplementasikan pengetahuan dalam bidang tekniknya untuk membuat alat penjemur yang tepat guna dengan memanfaatkan lahan yang terbatas, yaitu di atas gudang penyimpanan terung dan teripang kering. Dengan menggunakan alat penjemur kaca tersebut, lama penjemuran menjadi 3 hari dari sebelumnya 7-10 hari, sehingga efektifitas alat penjemur tersebut telah terbukti; (d) Pengurusan PIRT sebagai legalitas produk untuk dikonsumsi. Dengan demikian, Integrated Programs (IP) yang dilaksanakan oleh tim Penmas FTIK berhasil dalam meningkatkan kesejahteraan warga Kelurahan Sukolilo Baru, Surabaya.
PEMBELAJARAN BAHASA INGGRIS EFEKTIF MELALUI LAGU ANAK-ANAK UNTUK SISWA MADRASAH IBTIDAIYAH
Authors: Kasdi Kasdi , Wijayanti Dina Novita 
Published: July 2020

<p><strong>ABSTRAK </strong></p><p>Posisi bahasa Inggris di Indonesia adalah sebagai bahasa asing. Mempertimbangkan hal tersebut, maka guru bahasa Inggris di Indonesia dituntut kreatif dalam menciptakan proses kegiatan belajar mengajar yang mudah, menyenangkan khususnya bagi siswa madrasah ibtidaiyah yang memiliki karakteristik yang bisa mempengaruhi suasana pembelajaran di kelas dan pemilihan strategi pembelajaran oleh guru. Diantara strategi tersebut adalah penggunaan lagu. Tujuan penelitian ini adalah untuk mengetahui contoh lagu anak-anak yang efektif, keuntungan penggunaan lagu anak-anak dan langkah-langkah efektif untuk pembelajaran Bahasa Inggris bagi siswa Madrasah Ibtidaiyah. Penelitian ini menggunakan pendekatan kualitatif khususnya penelitian kepustakaan. Datanya berupa data sekunder yakni 2 jurnal dengan topik serupa dari peneliti terdahulu. Metode pengumpulan data yang dilakukan adalah dokumentasi. Hasil dari penelitian menujukkan bahwa ada 20 contoh lagu anak-anak yang efektif untuk pembelajaran bahasa Inggris bagi siswa madrasah ibtidaiyah. Penggunaan lagu anak-anak untuk pembelajaran Bahasa Inggris menunjukkan bahwa lagu bisa meningkatkan antusias anak-anak untuk belajar bahasa Inggris karena pembelajaran yang menyenangkan dan tidak terasa kaku sedangkan langkah-langkah yang dilakukan untuk menciptakan pembelajaran Bahasa Inggris yang efektif adalah guru Bahasa Inggris harus mempertimbangkan beberapa aspek yakni jenis lagu, jumlah siswa, tipe kegiatan pembelajaran dengan lagu, dan karakter siswa .</p><p> </p><p><strong>Kata Kunci</strong>: Pembelajaran Efektif, Bahasa Inggris, Lagu Anak-Anak, Siswa Madrasah Ibtidaiyah</p><p> </p><p> </p><p> </p><p><strong> تجريد</strong></p><p>موقف الإنجليزية في اندونيسيا هو كلغة أجنبية. النظر في هذا، وهو مدرس اللغة الإنجليزية في اندونيسيا طالب المبدع في خلق عملية التعلم التي هي سهلة وممتعة وخاصة للطلاب المدارس الدينية الذين لديهم الخصائص التي يمكن أن تؤثر على بيئة التعلم في الفصول الدراسية واختيار استراتيجية التعلم من قبل المعلم. ومن بين هذه الاستراتيجيات هي استخدام الأغنية. وكان الغرض من هذه الدراسة هو تحديد أمثلة من أغاني الأطفال التي على نحو فعال، يكسب استخدام التدابير أغنية وفعالة للأطفال لتعلم اللغة الإنجليزية لطلاب المدارس الحكومية الابتدائية. استخدمت هذه الدراسة المنهج الكيفي، وخاصة الأدب البحوث. البيانات في شكل بيانات الثانوية أن اثنين من المجلات في موضوعات مشابهة من الباحثين السابق. طريقة جمع البيانات يستخدم الوثائق. وأظهرت نتائج الدراسة أن هناك 20 نماذج من أغاني الأطفال هي فعالة لتعلم اللغة الإنجليزية لطلاب المدارس الدينية. وأظهر استخدام أغاني الأطفال لتعلم اللغة الإنجليزية أن الأغاني يمكن أن تزيد من حماسة الأطفال لتعلم اللغة الإنجليزية لأن التعلم هو متعة ولا يشعر قاسية في حين يتم اتخاذ خطوات لإنشاء تعلم اللغة الإنجليزية هي أن أحد مدرسي اللغة الإنجليزية فعال تنظر بعض جوانب وأنواع الأغاني، وعدد من الطلاب، ونوع من أنشطة التعلم مع الأغنية، وشخصية الطلاب.</p>كلمات البحث: التعلم الفعالة، الانجليزية، أغاني الأطفال، طلاب المدارس الحكومية الابتدائية
Analisis Kompetensi Pedagogik Guru Sekolah Dasar Di UPTD Pendidikan Banyumanik Kota Semarang
Authors: Afandi Muhamad , Wahyuningsih Sri 
Published: July 2020

Tujuan dari penelitian ini adalah untuk mendeskripsikan kompetensi peagogik Guru sekolah Dasar di UPTD Pendidikan Banyumanik Kota Semarang. Penelitian ini menggunakan metode deskriptif kuantitatif. Sampel penelitian ini adalah 162 guru Sekolah Dasar yang dipilih dengan teknik random sampling. Intrumen yang digunakan penelitian ini lembar penilaian, Intrumen penelitian terdiri 50 item pernyataan, dan 10 indikator kompetensi peagogik Guru Sekolah Dasar. Hasil penelitian menunjukkan bahwa pada indikator kemampuan guru menguasai karakteristik peserta didik adalah baik (81.8%), kemampuan guru menguasai teori belajar dan prinsip-prinsip pembelajaran yang mendidik adalah baik (77.1%), kemampuan guru mengembangkan kurikulum yang terkait dengan mata pelajaran/bidang pengembangan yang diampu adalah baik (82%), kemampuan guru menyelenggarakan pembelajaran yang mendidik adalah baik (85.2%), kemampuan guru memanfaatkan teknologi informasi dan komunikasi untuk kepentingan pembelajaran adalah baik (77.6%), kemampuan guru memfasilitasi pengembangan potensi peserta didik untuk mengaktualisasikan berbagai potensi yang dimiliki adalah baik (84.6%), Kemampuan guru berkomunikasi secara efektif, empatik, dan santun dengan peserta didik adalah baik (87.8%), Kemampuan guru menyelenggarakan penilaian proses dan hasil belajar adalah baik (82.1%), kemampuan guru memanfaatkan hasil penilaian untuk kepentingan pembelajaran adalah baik (87%), Kemampuan guru melakukan tindakan reflektif untuk peningkatan kualitas pembelajaran adalah cukup baik (74.7%). Secara keseluruhan kompetensi pedagogik guru Sekolah Dasar di UPTD Pendidikan Banyumanik adalah baik (81,3%).
Implementation of the First US Sugar-Sweetened Beverage Tax in Berkeley, CA, 2015–2019
Authors: Falbe Jennifer , Grummon Anna H. , Rojas Nadia , Ryan-Ibarra Suzanne , Silver Lynn D. , Madsen Kristine A. 
Published: July 2020

Objectives. To identify lessons learned from implementation of the nation’s first sugar-sweetened beverage (SSB) excise tax in 2015 in Berkeley, California. Methods. We interviewed city stakeholders and SSB distributors and retailers (n = 48) from June 2015 to April 2017 and analyzed records through January 2019. Results. Lessons included the importance of thorough and timely communications with distributors and retailers, adequate lead time for implementation, advisory commissions for revenue allocations, and funding of staff, communications, and evaluation before tax collection begins. Early and robust outreach about the tax and programs funded can promote and sustain public support, reduce friction, and facilitate beverage price increases on SSBs only. No retailer reported raising food prices, indicating that Berkeley’s SSB tax did not function as a “grocery tax,” as industry claimed. Revenue allocations totaled more than $9 million for public health, nutrition, and health equity through 2021. Conclusions. The policy package, context, and implementation process facilitated translating policy into public health outcomes. Further research is needed to understand long-term facilitators and barriers to sustaining public health benefits of Berkeley’s tax and how those differ from facilitators and barriers in jurisdictions facing significant industry-funded repeal efforts.
Bioclastic accumulation in a lake rift basin: The Early Cretaceous coquinas of the Sergipe–Alagoas Basin, Brazil
Authors: Rigueti Ariely L. , Dal' Bó Patrick Führ , Borghi Leonardo , Mendes Marcelo 
Published: July 2020

ABSTRACTCoquinas constitute widespread deposits in lacustrine, estuarine, and shallow marine settings, where they are a valuable source of information on environmental conditions. Thick coquina successions were deposited in a series of lacustrine rift basins that formed along the Brazilian Continental Margin during the early stages of the opening of the South Atlantic Ocean, in the Early Cretaceous. In the Sergipe–Alagoas Basin, the coquina sequence, equivalent to the Morro do Chaves Formation, crops out in the Atol Quarry, and is considered a relevant analog for the economically important hydrocarbon reservoirs in the Pre-salt strata (Barremian to Aptian) of the Campos Basin (Pampo, Badejo, and Linguado oil fields), which occur only in the subsurface. The aim of this study is to generate a depositional and stratigraphic model through facies and stratigraphic analyses of a well core. These analyses allowed the geological characterization of the Morro do Chaves Formation and of its transition to the adjacent stratigraphic units, the Coqueiro Seco Formation above and the Penedo Formation below, contributing to the growing knowledge of sedimentation in rift basins and exploratory models in hydrocarbon-producing reservoirs. Facies analysis consists of sedimentological, taphonomic, and stratigraphic features of the rocks. Fourteen depositional facies were recognized, stacked into low-frequency and high-frequency, deepening-upward and shallowing-upward cycles driven by the interaction between climate and tectonism. A depositional model is presented, based on the correlation between well-core and outcrop data described in previous studies, providing insights into the spatial distribution of facies. The detailed analysis of facies and stacking patterns sheds light on depositional processes, paleoenvironmental conditions, and the evolution of the system through time, so we may better understand analogous deposits in the geological record.
PRESERVATION OF NEUROPTERIS OVATA IN ROOF SHALE AND IN FLUVIAL CREVASSE-SPLAY FACIES (LATE PENNSYLVANIAN, SYDNEY COALFIELD, CANADA). PART I: AN INFRARED-BASED CHEMOMETRIC MODEL
Authors: D'ANGELO JOSÉ A. , ZODROW ERWIN L. 
Published: July 2020

ABSTRACTAnalytical questions relating to the influence of sedimentation on the preservation states of Carboniferous plant fossils are seldom addressed in the literature. Here we address specifically the influence facies differences have on preservation states and suggest how they can be analyzed. The case study involves the seed fern Neuropteris ovata (Hoffmann) that occurs as opaque pinnules in the roof shale and as transparent pinnules in an associated crevasse-splay of the basal Cantabrian in age, Point Aconi Coal Seam, Sydney Coalfield, Canada. The color differences imply different molecular pathways for organic matter transformation over geological time, which resulted in production of compression fossils in the roof shale and fossilized-cuticle in the crevasse-splay, respectively. Fourier transform infrared spectroscopy methods are used to quantify functional groups, and the derived data are chemometrically evaluated. Results indicate that the compressions are, as anticipated, characterized in the crevasse-splay facies by a predominantly aromatic composition. The fossilized-cuticles, however, are mainly characterized by oxygen-containing aliphatics, confirming the influence of facies changes on preservation states of the species studied. Implications for preservation, taxonomy, and paleoecology are emphasized.