bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synergism and antagonism of bacterial-viral co-infection in the upper respiratory tract
Authors: Manna Sam , McAuley Julie , Jacobson Jonathan , Nguyen Cattram D. , Ullah Md Ashik , Williamson Victoria , Mulholland E. Kim , Wijburg Odilia , Phipps Simon , Satzke Catherine 
Published: November 2020

ABSTRACTStreptococcus pneumoniae(the pneumococcus) is a leading cause of pneumonia in children under five years old. Co-infection by pneumococci and respiratory viruses enhances disease severity. Little is known about pneumococcal co-infections with Respiratory Syncytial Virus (RSV). Here, we developed a novel infant mouse model of co-infection using Pneumonia Virus of Mice (PVM), a murine analogue of RSV, to examine the dynamics of co-infection in the upper respiratory tract, an anatomical niche that is essential for host-to-host transmission and progression to disease. Coinfection increased damage to the nasal tissue and increased production of the chemokine CCL3. Pneumococcal nasopharyngeal density and shedding in nasal secretions were increased by co-infection. In contrast, co-infection reduced PVM loads in the nasopharynx, an effect that was independent of pneumococcal strain and the order of infection. We showed this ‘antagonistic’ effect was abrogated using a pneumococcal mutant deficient in capsule production and incapable of nasopharyngeal carriage. The pneumococcal-mediated reduction in PVM loads was caused by accelerated viral clearance from the nasopharynx. Although these synergistic and antagonistic effects occurred with both wild-type pneumococcal strains used in this study, the magnitude of the effects was strain dependent. Lastly, we showed that pneumococci can also antagonize influenza virus. Taken together, our study has uncovered multiple novel facets of bacterial-viral co-infection. Our findings have important public health implications, including for bacterial and viral vaccination strategies in young children.
Phage Commander, a software tool for rapid annotation of bacteriophage genomes using multiple programs
Authors: Lazeroff Matt , Harris Sarah L. , Tsourkas Philippos K. 
Published: November 2020

ABSTRACTThe number of sequenced phage genomes is growing at an exponential rate. The majority of newly sequenced phage genomes are annotated by one or more of several freely-available auto-annotation programs. No program has been shown to consistently outperform the others; thus the choice of which program to use is not obvious. We present the software Phage Commander for rapid annotation of phage genomes using multiple auto-annotation programs. Phage Commander runs a phage genome sequence through nine auto-annotation programs and integrates the results within a single output. Phage Commander generates properly formatted output files for direct export to NCBI GenBank. Users can select the threshold for determining which genes should be exported. Phage Commander was benchmarked using eight high-quality phage genomes whose genes have been identified through experiments. Results show that the best results are obtained by exporting genes identified by at least two or three of the nine auto-annotation programs.
Emerging themes of public-private partnership application in developing smart city projects: a conceptual framework
Authors: Liu Tingting , Mostafa Sherif , Mohamed Sherif , Nguyen Tuan Son 
Published: November 2020

PurposeCities are facing challenges with their smart city agenda due to tighter budget constraints, varied interests of different stakeholders and increasing needs of technological innovation. Therefore, cities are partnering with private organisations to advance smart city projects. This research critically analyses the existing research published on public-private partnerships (PPPs) for the development of smart city projects and aims to identify the emerging themes and recommend mechanisms and strategies for improved use of smart city PPPs.Design/methodology/approachThe content/textual analysis was conducted on 52 research publications relating to PPP and smart city from 2001 to 2020. With the assistance of the Leximancer software, the related literature was systematically analysed and synthesised to present the emerging themes of PPP application within the smart city context.FindingsThe analyses reveal that smart city PPPs mainly concentrated on building new or improving existing infrastructure. The research identifies five themes on PPP application for smart city development: (1) Technological innovation integration and increased risk profile, (2) Smart citizen engagement and participatory governance, (3) Data sharing and information security, (4) Transformation of PPP process and approach and (5) PPPs for urban sustainability. This research consolidates these five themes in a proposed sustainable public-private-people partnership (PPPP) framework.Originality/valueThis research provides a new perspective on rethinking the extant PPP models by highlighting the emerging themes in the PPP application for smart city development. This study provides useful recommendations for smart city infrastructure project partnership and engagement among the public and private sectors, and the city residents.
Consumers’ awareness of the EU’s protected designations of origin logo
Authors: Goudis Alexandra , Skuras Dimitris 
Published: November 2020

PurposeProtected designation of origin (PDO) and protected geographical indication (PGI) products form the core of the European Union (EU) quality food policy. Low and fragmented logo recognition perils the entire plan. This work aims to provide a “classification” of European consumers as regards logo awareness based on generic demographic and socio-economic characteristics and to test hypotheses relating PDO awareness with the purchasing behaviour of consumers.Design/methodology/approachThe work utilises publicly available pan-European databases collected from Eurobarometer in four rolling surveys from 2012 to 2017. The statistical analysis exploits the spatially nested nature of the data.FindingsThe “logo aware” consumer is distinctively different from the average representative European consumer. A range of demographic, human capital and socio-economic characteristics and behavioural and attitudinal traits differentiate the consumers who are aware of the logo. Country and region effects are vital.Research limitations/implicationsBenefits of large and representative samples accrue by utilising available Eurobarometer surveys. This comes at a cost. The individual researcher has no control over the questions included in the questionnaire.Practical implicationsConsumer classification forms the basis of awareness-raising strategies. It reveals the numerous segments of aware and non-aware consumers and opens a discussion about tools and methods to reach out to the European consumer.Originality/valueThis analysis holds an exact pan-European perspective and incorporates consumers' characteristics, behaviour, attitudes and country and region effects.
A comparative benchmark model for SMEs: viable entrepreneur emotional intelligence
Authors: Karia Noorliza 
Published: November 2020

PurposeBesides small- and medium-sized enterprises' (SMEs) constraints, there is a lack of critical observations of the human capital model naturally inspiring themselves from within. Therefore this paper exposes the factors of emotional intelligence (EI) that make entrepreneurs gain sustainable competitiveness.Design/methodology/approachA data of self-administered survey from 397 SMEs in Malaysia was investigated using regression analysis.FindingsThe results reveal factors of EI comprised of self-confidence, self-innovation, self-inspiration and self-vision that have significant positive impacts on entrepreneurial performance. Amazingly, EI contributes almost 30% of the success, where self-vision and self-innovation are the robust EI to strengthen and sustain entrepreneurial performance. In contrast, self-confidence and self-inspiration are generic EI of human capital and easy to be applied by rivals.Research limitations/implicationsThe study provides a comparative benchmark model for SMEs, managers and entrepreneurs inspiring themselves from within that they can emulate and attain the same success. SMEs can obtain success by investing and culturing EI factors within themselves.Practical implicationsThe study provides a comparative benchmark model for SMEs and managers inspiring themselves from within and expands the theory of heterogeneous SMEs and the human capital to sustainable business and competitiveness. SMEs can obtain success through capitalizing human capital attributes within themselves.Originality/valueThe study is the first providing the viable model for SMEs or entrepreneurs leading themselves from within, to their action, behaviour, decision and achievement or the performance mechanism with a benchmark model of entrepreneur EI as a booster.
The acquisition of teamwork skills in university students through extra-curricular activities
Authors: de Prada Creo Elena , Mareque Mercedes , Portela-Pino Iago 
Published: November 2020

PurposeThis study aims to determine whether university students are successfully acquiring or improving skills related to teamwork through a variety of extra-curricular activities, such as sports, music, volunteering, international group work experiences and professional practices.Design/methodology/approachDescriptive statistics have been calculated to evaluate the normal behaviour of the variables. Accidental sampling was used via a cross-curricular study with a quasi-experimental design. An analysis of means was performed using the Student's t-test.FindingsThe results show the students to have highly developed interpersonal and communication skills, followed by adaptation and decision-making skills. The lowest scores corresponded to coordination and leadership skills. On the other hand, a significant correlation was established between extra-curricular activities and the acquisition of essential teamwork skills.Originality/valueThis study can confirm the important relation between extra-curricular activities and the acquisition of the teamwork skills that play a vital role in the overall development of our students, as well as for their integration into the job market, with particular emphasis on the acquisition of leadership skills which students are most lacking in, but which have shown to improve with any of the proposed activities. The promotion of the extra-curricular activities by the University, could greatly support our students' soft skills acquisition and complement their education.
Beyond human capital: student preparation for graduate life
Authors: Benati Kelly , Fischer Juan 
Published: November 2020

PurposeThis research moves beyond a focus on employability skills and explores student perceptions of preparedness for graduate life in a more holistic manner.Design/methodology/approachFinal-year business students were asked to outline their concerns regarding graduate life and the personal and professional challenges anticipated in their careers. The results are presented in the context of graduate capitals, which is a broader view than the more traditional skills-based approach.FindingsThe results indicate students do not feel underprepared for the workplace in terms of human capital, social capital, cultural capital and identity capital. However, many students feel inadequately prepared in terms of psychological capital and their ability to deal with the expected challenges of the workplace such as stress, long hours and the demands of a professional environment.Research limitations/implicationsThis study extends our knowledge of student preparation for the workplace and suggests research opportunities to better understand psychological capital development in graduates.Practical implicationsGreater confidence and a perception of preparedness may be increased for graduates if opportunities for psychological capital development and increased promotion of its importance are enhanced.Social implicationsThe results encourage a more holistic approach to employability in graduates and have relevance for all stakeholders concerned with graduate outcomes and workplace transition.Originality/valueThe paper presents work-readiness in the context of graduate capitals, which is broader than the traditional skills-based approach. It also focuses on student perceptions of their level of preparation for the workplace. This has enabled results which highlight psychological capital development as a key area in which students feel underprepared.
Shipment sizing for autonomous trucks of road freight
Authors: Chen Chun-Miin (Jimmy) , Lu Yajun 
Published: November 2020

PurposeUnprecedented endeavors have been made to take autonomous trucks to the open road. This study aims to provide relevant information on autonomous truck technology and to help logistics managers gain insight into assessing optimal shipment sizes for autonomous trucks.Design/methodology/approachEmpirical data of estimated autonomous truck costs are collected to help revise classic, conceptual models of assessing optimal shipment sizes. Numerical experiments are conducted to illustrate the optimal shipment size when varying the autonomous truck technology cost and transportation lead time reduction.FindingsAutonomous truck technology can cost as much as 70% of the price of a truck. Logistics managers using classic models that disregard the additional cost could underestimate the optimal shipment size for autonomous trucks. This study also predicts the possibility of inventory centralization in the supply chain network.Research limitations/implicationsThe findings are based on information collected from trade articles and academic journals in the domain of logistics management. Other technical or engineering discussions on autonomous trucks are not included in the literature review.Practical implicationsLogistics managers must consider the latest cost information when deciding on shipment sizes of road freight for autonomous trucks. When the economies of scale in autonomous technology prevail, the classic economic order quantity solution might again suffice as a good approximation for optimal shipment size.Originality/valueThis study shows that some models in the literature might no longer be applicable after the introduction of autonomous trucks. We also develop a new cost expression that is a function of the lead time reduction by adopting autonomous trucks.
Supply risk identification in manufacturing supply networks
Authors: Wiedenmann Marc , Größler Andreas 
Published: November 2020

PurposeManaging supply risk is gaining in importance in the tightly interconnected global economy. Identifying the relevant risks is the foundation of any risk management process. Therefore, the purpose of this paper first is to provide a short introduction to supply risk management, before focussing on the identification of such risks in more detail. A holistic framework of the identified supply risks, which distinguishes between risk dimensions and risk factors in manufacturing upstream supply networks, is proposed.Design/methodology/approachThis study applies a mixed methods research approach. Data are collected based on a structured literature review in combination with the analysis of company-specific documents and semi-structured expert interviews. Subsequently, a deductive content analysis is carried out to derive a holistic framework of supply risks, adapted to the manufacturing industry. For the external validation of the conceptual supply risk framework, additional experts from several manufacturing companies were consulted.FindingsBased on the definition and delimitation of supply risk, a categorization of supply risks is developed. The relevant literature, as well as expert interviews, lead to the distinction of six supply risk dimensions: quality, delivery, collaboration, economic, ambience and compliance. A total of 27 risk factors can be assigned to these dimensions. A holistic foundation for the management of supply risk is thus created.Originality/valueThis study provides a holistic framework of relevant supply risks in the context of the manufacturing industry. This overview of identified risks offers a novel perspective on risk in manufacturing supply networks that can be helpful in researching assessment and mitigation strategies. Despite the high relevance and popularity of this field of research, such an overview with a focus on manufacturing had not yet been made available in the literature. Building thereon, management approaches can now be developed to handle the risk arising from the upstream of the supply network.
Adverse childhood experiences in relation to drug and alcohol use in 30 days prior to incarceration in a county jail
Authors: Eaves Emery R. , Camplain Ricky L. , Lininger Monica R. , Trotter II Robert T. 
Published: November 2020

Purpose
The purpose of this paper is to characterize the relationship between adverse childhood experiences (ACEs) and substance use among people incarcerated in a county jail.

Design/methodology/approach
A questionnaire was administered to 199 individuals incarcerated in a Southwest county jail as part of a social-epidemiological exploration of converging comorbidities in incarcerated populations. Among 96 participants with complete ACEs data, the authors determined associations between individual ACEs items and a summative score with methamphetamine (meth), heroin, other opiates and cocaine use and binge drinking in the 30 days prior to incarceration using logistic regression.

Findings
People who self-reported use of methamphetamine, heroin, other opiates or cocaine in the 30 days prior to incarceration had higher average ACEs scores. Methamphetamine use was significantly associated with living with anyone who served time in a correctional facility and with someone trying to make them touch sexually. Opiate use was significantly associated with living with anyone who was depressed, mentally ill or suicidal; living with anyone who used illegal street drugs or misused prescription medications; and if an adult touched them sexually. Binge drinking was significantly associated with having lived with someone who was a problem drinker or alcoholic.

Social implications
The findings point to a need for research to understand differences between methamphetamine use and opiate use in relation to particular adverse experiences during childhood and a need for tailored intervention for people incarcerated in jail.

Originality/value
Significant associations between methamphetamine use and opiate use and specific ACEs suggest important entry points for improving jail and community programming.
Malmö – the skateboarding city: a multi-level approach for developing and marketing a city through user-driven partnerships
Authors: Book Karin , Svanborg Edén Gustav 
Published: November 2020

PurposeThe purpose of this paper is to examine how skateboarding as a community, sport and cultural phenomenon can become integrated into and drive the development, branding and marketing of a city (Malmö).Design/methodology/approachThis paper is produced through a communicative co-constructed process of one scholar and one practitioner within the skateboarding field. Through the narrative told by the practitioner, and with basis in the established understanding and conceptualization of place marketing through sport, success factors of the skateboarding initiatives in Malmö are identified.FindingsThe skateboarding story of Malmö fits well into the established conceptualization of place branding and marketing, neoliberalism and urban entrepreneurialism. Also, it demonstrates the power of a unique user-driven partnerships between skaters, a non-profit organization and public institutions to create a skateboard-friendly city and as a consequence a strong internationally renowned skate-image. The multi-level, multi-content approach is founded in shared values and mutual benefits. Instead of fitting a phenomenon into an outward-oriented image-strategy, skateboarding as a sport and culture has been allowed to develop organically, creating a credible and unique image for Malmö.Originality/valueThis study adds to the literature on sport and city marketing/branding by developing a deeper, empirically founded, understanding of how to combine top-down and bottom-up approaches in urban development, marketing and branding. The results have scientific as well as practical value.
Does human capital pay? The influence of leader human capital and employee human capital on leader bonus earnings
Authors: Harris Christopher M. , Brown Lee W. 
Published: November 2020

PurposeThe human capital of a leader and the human capital of the employees who work for the leader can impact the bonus earned by the leader. Little to no research has examined data that includes the maximum potential bonus that could be earned by a leader and the actual bonus earned. This information provides a closer examination of leader performance and the impacts of leader and employee human capital on the bonus earned by the leader.Design/methodology/approachThe authors use a sample of NCAA college football teams and head coaches over two years to test their hypotheses. They measure the human capital of the team and the human capital of the head coach. In addition, the authors assess the percentage earned by the head coach of the maximum potential bonus possible.FindingsThe authors find that a coach's human capital and the human capital of their team positively and significantly predict the percentage of the maximum possible bonus earned by the head coach.Practical implicationsThe results of this study indicate the importance of leader human capital to a leader's ability to earn more of their maximum potential bonus. Additionally, if a leader is able to surround himself or herself with highly talented employees, it will benefit the leader in terms of the amount of bonus earned.Originality/valueThis study extends previous research to provide a more complete picture of factors that influence a leader's ability to earn more of their maximum possible bonus. The authors’ findings that both the human capital of the leader and the human capital of employees who work for the leader impact the amount of bonus earned by the leader add value to human resource management research. Specifically, when examining factors that impact a leader's bonus earnings, it is important to consider not only characteristics of the leader but also factors apart from the leader, such as the leader's employees.
Buying subject-matter expertise: an innovative approach to business classes
Authors: English Philip , Gordon Rachel 
Published: November 2020

PurposeThis paper introduces a new instructional design for executive programs that combined a flipped classroom methodology and experiential learning to address the challenge of teaching highly technical material in a compressed time frame. In practice, when decision-making executives lack technical expertise and face a highly technical problem, they contract for subject-matter expertise (SME) within the firm or through hiring consultants. The authors show how this can be done in a classroom setting to enhance the learning experience.Design/methodology/approachThe classroom approach utilizes students from other programs as analysts for executive MBA (EMBA) teams faced with case analysis that involves technical issues in finance. The analysts act as subject-matter experts for the EMBA students.FindingsExecutive student learning is not eroded by relying on the analysts, and, moreover, the use of analysts enhances EMBA student understandingPractical implicationsExecutives are able, in a short time frame, to produce high quality analysis by utilizing the subject-matter experts. Executives also learn how to ask the right questions and evaluate the quality of the analysis created by the subject-matter experts. The subject-matter experts, who are also students, derive added benefits of an employment experience in finance, learning how to interpret instructions about the analysis and how to respond to feedback.Originality/valueThe paper illustrates a new course design where the course's technical analysis aspects mimic work environments enhancing student learning.