bluuebunny/crossref_metadata_2025_split huggingface dataset:
How does future focus promote study engagement? A moderated mediation model of self‐esteem and dispositional awe
Authors: Zhang Furong , Feng Shiting , Li Jie 
Published: October 2020

AbstractSufficient engagement in studying promotes students' academic performance and ability to compete in the job market. In this study, we explore the role of future focus and dispositional awe in stimulating college students' study engagement. To examine our hypotheses, we conducted a questionnaire survey with 237 students from a national college in China. The results indicate that future focus is positively related to study engagement and that self‐esteem mediates this relationship. Moreover, the mediating effect of self‐esteem is moderated by dispositional awe such that the mediation relationship is weaker when the level of awe is higher. Implications and directions for future research are discussed.
How teachers' perceptions of the parent–teacher relationship affect children's risk for early childhood expulsion
Authors: Zulauf‐McCurdy Courtney A. , Zinsser Katherine M. 
Published: October 2020

AbstractRates of expulsion from early care and education settings (e.g., childcare and preschool programs) exceed those in K‐12, and relatively little is known of how to prevent such disciplinary decisions. In addition, expulsion disproportionately affects children of color, especially boys. The present study explores a potential protective strategy existent in all early care and education settings, the parent–teacher relationship. Surveys with early childhood teachers (N = 295) outline the association between teachers' perceptions of the parent–teacher relationship and a child's risk for expulsion. Findings indicate that teachers' perceptions of high‐quality parent–teacher relationships are related to a lower risk for expulsion for children who have not been expelled, with the strongest association found for Black children. In contrast, for children identified as previously expelled, we found no association between teachers' perceptions of the parent–teacher relationship and future expulsion risk. Each finding will be described in detail with an eye towards implications and intervention.
Development of recoverable and recyclable Fe3O4‐supported organocatalysts for ring‐opening polymerization
Authors: Chen Yang , Xiao Wenhao , Zhang Jie , Bu Minglu , Zhang Xiaoqing , Chen Anfu , Xu Jinbao , Lei Caihong 
Published: October 2020

AbstractAn iminotris(dimethylamino)phosphorane (HMP1) phosphazene superbase has been anchored onto poly(hexachlorocyclotriphosphazene‐co‐4,4′‐sulfonyldiphenol) (PZS)‐coated Fe3O4 magnetic nanoparticles (MNPs) through efficient phosphorous‐chloride (from PZS surface) and imino (from HMP1) reaction. Subsequently, these novel heterogeneous Fe3O4@PZS@HMP1 catalysts have been successfully utilized in the ring‐opening polymerization of ε‐caprolactone (ε‐CL) and δ‐valerolactone (δ‐VL). Notably, such catalysts can be easily removed from the reaction mixture and reused 3 times without obvious activity loss.
The association between anxiety and esophageal cancer: A nationwide population‐based study
Authors: Zhu Juan , Zhou Yueyue , Ma Shanrui , Chen Ru , Xie Shuanghua , Liu Zhengkui , Li Xinqing , Wei Wenqiang 
Published: October 2020

AbstractObjectiveResearch on generalized anxiety disorder (GAD) and its association with esophageal cancer (EC) is sparse. The study aimed to explore the association between GAD and EC.MethodsA multicenter, population‐based study in high‐risk regions for EC (ECHRRs) was conducted from 2017 to 2019. All participants received free endoscopy screening. If the esophageal endoscopy results were suspicious, the pathological biopsy was performed to confirm normal, esophagitis, low‐grade intraepithelial neoplasia (LGIN), high‐grade intraepithelial neoplasia (HGIN), and EC. Information on participants' exposure to risk factors was collected. GAD was assessed with Generalized Anxiety Disorder Scale‐7.ResultsWith esophageal endoscopy, 25,650 participants in ECHRRs were examined, 9586 of whom were suspicious and confirmed by esophageal pathology. The detection rate of EC and precancerous lesions was 6.83% (1751/25,650), with 1377 LGIN (5.37%), 272 HGIN (1.06%), and 102 EC (0.40%) cases. The overall mean GAD score (95% CI) and prevalence among 25,650 participants with endoscopy were 1.96 (1.93–1.99) and 16.90%, respectively. The mean GAD score and prevalence among 9586 participants with pathology were 1.96 (1.91–2.02) and 17.98%, respectively. The mean GAD scores of patients confirmed with normal, esophagitis, LGIN, HGIN, and EC were 1.73 (1.62–1.85), 1.91 (1.85–1.97), 1.94 (1.80–2.08), 3.98 (3.73–4.23). and 2.97 (2.49–3.45), respectively (p < 0.001). The corresponding prevalence of GAD were 5.21%, 18.72%, 17.72%, 43.75%, and 36.27%, respectively (p < 0.001). The age‐ and gender‐adjusted odds ratios (ORs) between GAD and each esophageal lesion type were 1.02 (0.99–1.04), 1.01 (0.98–1.04), 1.27 (1.21–1.33), and 1.16 (1.08‐1.24), respectively. The ORs (95% CIs) of the positive associations were 1.08 (1.05–1.12), 1.03 (0.99–1.07), 1.35 (1.29–1.42), and 1.19 (1.10–1.29) after further adjustment for potential confounders (all p < 0.001). Sensitivity analysis showed that the positive association persisted.ConclusionsGAD was significantly higher in patients with EC and precancerous lesions. Focusing on and alleviating anxiety in high‐risk groups (including patients with HGIN and EC) may be an effective strategy for EC prevention and control. Further prospective studies are warranted to validate the results.
Enhancing integrated psychosocial oncology through leveraging the oncology social worker's role in collaborative care
Authors: Courtnage Tiffany , Bates Nicole E. , Armstrong Anne A. , Seitz M. Katherine , Weitzman Tammy S. , Fann Jesse R. 
Published: October 2020

AbstractObjectiveThe collaborative care model is effective in delivering evidence‐based psychosocial oncology care. Social workers comprise the largest proportion of psychosocial oncology providers in the United States. This study describes the process and perceptions of clinical oncology social workers at a large comprehensive cancer center who transitioned to practicing as care managers within collaborative care.MethodsWe describe the process of engaging clinical oncology social workers as care managers as part of the implementation of collaborative care at the Seattle Cancer Care Alliance. We then present survey results from 2017 and 2020 of participating social workers' perceptions of the collaborative care model's advantages and disadvantages.ResultsSince the implementation of collaborative care at our institution, key functions of the social worker as care manager were defined. The majority of social workers surveyed in 2017 and 2020 agreed that collaborative care led to improved clinical outcomes, timely access to care, and greater patient satisfaction. They also reported professional advantages: more interdisciplinary team integration, working at the top of their licensure, and improved job satisfaction. Challenges identified included missing important patient needs and creating extra work burden for social workers.ConclusionsOncology social workers can be successfully deployed as care managers within a collaborative care model, thus leveraging existing clinical staff to address unmet psychosocial patient needs. This model is feasible and sustainable in a large academic cancer center, requires minimal additional resources, and is favorably viewed by participating social workers in terms of perceived benefits to patients and their own professional roles.
Corrosion prevention of crude and vacuum distillation column overheads in a petroleum refinery: A field monitoring study
Authors: Subramanian Chidambaram 
Published: October 2020

AbstractThe aim of the present work is to monitor dew point corrosion of crude and vacuum distillation column overhead section in a petroleum refinery. The material of construction of overhead line pipe was carbon steel. The state of art of crude unit process was introduced. The corrosion and associated hydrolyzing mechanisms were briefly described. The crude processing in a petroleum refinery was extremely dynamic and thus field monitoring attempts were made, which provides some useful information on structural integrity of column downstream equipments. The demulsifier, neutralizer, and corrosion inhibitor were mixed in crude unit at specific locations for corrosion prevention. Field monitoring includes evaluation of pH and chloride content of desalter extracted water and overhead condensed water, Base Sediment & Water (BS&W) and chloride content of as‐received & desalted crude, and iron content of overhead condensed water. Furthermore, corrosion coupon was installed in overhead section to obtain the actual corrosion rate. All the field study was conducted for a specified period. The acidity, chloride concentration, and iron loss of condensed water confirmed that acidic corrosion was under control. The corrosion rate of the installed coupons confirmed that corrosion rate was within the specified limit. The results revealed in this paper intended for refinery operators and corrosion engineers involved in understanding of actual process parameters in prevention of overhead acidic corrosion.
Heterokaryotic state of a point mutation (H249Y) in SDHB protein drives the evolution of thifluzamide resistance in Rhizoctonia solani
Authors: Miao Jianqiang , Mu Wenjun , Bi Yang , Zhang Yanling , Zhang Shaoliang , Song Jizhen , Liu Xili 
Published: October 2020

AbstractBACKGROUNDSheath blight, caused by Rhizoctonia solani, can be effectively controlled by application of the succinate dehydrogenase inhibitor thifluzamide. Although the risk of resistance to thifluzamide in R. solani had been reported, the thifluzamide‐resistance mechanism and the evolution of thifluzamide‐resistance in R. solani have not been investigated in detail.RESULTSNo differences were found between the sequences of proteins SDHA, SDHC, and SDHD in thifluzamide‐sensitive isolates and thifluzamide‐resistant mutants, but a single point mutation H249Y was found in SDHB. Two different types of thifluzamide‐resistant R. solani mutants were characterized: homokaryotic, carrying only the resistance allele; and heterokaryotic, retaining the wild‐type allele in addition to the resistance allele. The resistance level differed according to the nuclear composition at codon 249 in the sdhB gene. Molecular docking results suggested that the point mutation (H249Y) might significantly alter the affinity of thifluzamide and SDHB protein. Heterokaryotic mutants were able to evolve into a homokaryon when repeatedly cultured on agar media or rice plants in the presence of thifluzamide, but thifluzamide treatment had no effect on the genotypes of homokaryotic mutants or sensitive isolates.CONCLUSIONThis study showed that H249Y in SDHB protein could cause thifluzamide resistance in R. solani. Fungicide application could promote heterokaryotic mutants to evolve into a homokaryon. © 2020 Society of Chemical Industry
Defining estimands using a mix of strategies to handle intercurrent events in clinical trials
Authors: Qu Yongming , Shurzinske Linda , Sethuraman Shanthi 
Published: October 2020

SUMMARYRandomized controlled trials (RCTs) are the gold standard for evaluation of the efficacy and safety of investigational interventions. If every patient in an RCT were to adhere to the randomized treatment, one could simply analyze the complete data to infer the treatment effect. However, intercurrent events (ICEs) including the use of concomitant medication for unsatisfactory efficacy, treatment discontinuation due to adverse events, or lack of efficacy may lead to interventions that deviate from the original treatment assignment. Therefore, defining the appropriate estimand (the appropriate parameter to be estimated) based on the primary objective of the study is critical prior to determining the statistical analysis method and analyzing the data. The International Council for Harmonisation (ICH) E9 (R1), adopted on November 20, 2019, provided five strategies to define the estimand: treatment policy, hypothetical, composite variable, while on treatment, and principal stratum. In this article, we propose an estimand using a mix of strategies in handling ICEs. This estimand is an average of the “null” treatment difference for those with ICEs potentially related to safety and the treatment difference for the other patients if they would complete the assigned treatments. Two examples from clinical trials evaluating antidiabetes treatments are provided to illustrate the estimation of this proposed estimand and to compare it with the estimates for estimands using hypothetical and treatment policy strategies in handling ICEs.
Robust control of the Hill's problem with drag
Authors: Limebeer David J. N. , Sabatta Deon 
Published: October 2020

SummaryThere are significant advantages associated with the analysis of satellite trajectory control problems in the Hill's analysis framework. As with the circular restricted three‐body problem (CRTBP) equations, the Hill's equations support three‐dimensional “halo” orbits that require station‐keeping control. These orbits are typically in regions of space close to a libration point. In most cases these orbits are unstable, with drag effects introducing uncertain exogenous forces. A two‐degree‐of‐freedom control strategy is used to maintain a pre‐selected orbit and introduce a quantifiable robust stability margin. The control study presented is based on a time‐periodic state feedback law, and a time‐periodic feed‐forward control that is based on a linearized drag model. The efficacy of these ideas is demonstrated by simulation.
Filtering homogeneous observers in control of integrator chains
Authors: Jbara Adam , Levant Arie , Hanan Avi 
Published: October 2020

SummaryAny homogeneous controller asymptotically stabilizing disturbed integrator chains can be coupled with the proposed robust homogeneous filtering observer. The type of convergence (in finite‐time, in fixed‐time to any ball or exponential) is determined by the sign of the system homogeneity degree (HD). Filtering high‐gain observers and sliding‐mode‐based observers/differentiators are important particular cases corresponding to zero and negative HDs, respectively. Stabilization accuracy is estimated in the presence of possibly unbounded sampling noises featuring locally bounded iterated integrals. Accurate stabilization and differentiation are demonstrated for extremely large noises.
Building Lexical Representations With Nonverbal Supports
Authors: Lawson‐Adams Jessica , Dickinson David K. 
Published: October 2020

AbstractHigh‐quality lexical representations are important for reading comprehension; however, prior research has focused primarily on the verbal aspects of these lexical representations. In this article, the authors argue for the importance of considering nonverbal representational elements of lexical knowledge and for more systematic attention to how nonverbal supports, such as gestures, pictures, and sounds, contribute to the acquisition of word knowledge. Drawing from various theoretical perspectives, the authors argue that the semantic content and the attention‐directing attributes of nonverbal supports are critical in assisting primary‐grade students in building high‐quality multimodal lexical representations. The authors examined the use of nonverbal supports in vocabulary studies for young learners and present implications about the role of nonverbal supports in students’ vocabulary acquisition. Results suggest that nonverbal scaffolds can help refine and deepen students’ knowledge of words for a variety of word types, including abstract words.
Humor as Political Possibility: Critical Media Literacy in LGBTQ+ Participatory Cultures
Authors: Shrodes Addie 
Published: October 2020

ABSTRACTThe author contributes new insights into everyday literacies in participatory cultures using a multimodal analysis of three LGBTQ+ reaction videos on YouTube. LGBTQ+ reaction videos respond, often comedically, to oppressive media forms and technologies. In the analysis, the author considers how reaction video makers draw on seven meaning‐making modes and multimodal techniques in digital composition to enact practices of critical media literacy, namely, to identify, interrogate, and disrupt dominant ideologies that undergird media forms and technologies. Through analytic video logging and multimodal analysis of video episodes, the author also examines the role of humor in enactments of these practices. The article forwards the conceptual framework of humor as political possibility made manifest in the range of ways that video makers construct slips of humor, compose multimodal parodies, and create satires that critique dominant ideologies and imagine new ways of being in the world. Examining literate activities in participatory cultures with a focus on LGBTQ+ identities has purchase to explicate possibilities to name, challenge, and transform dominant ideologies toward more just futures.
Brachyury engineers cardiac repair competent stem cells
Authors: Li Mark , Yamada Satsuki , Shi Ao , Singh Raman Deep , Rolland Tyler J. , Jeon Ryounghoon , Lopez Natalia , Shelerud Lukas , Terzic Andre , Behfar Atta 
Published: October 2020

Abstract
To optimize the regenerative proficiency of stem cells, a cardiopoietic protein-based cocktail consisting of multiple growth factors has been developed and advanced into clinical trials for treatment of ischemic heart failure. Streamlining the inductors of cardiopoiesis would address the resource intensive nature of the current stem cell enhancement protocol. To this end, the microencapsulated-modified-mRNA (M3RNA) technique was here applied to introduce early cardiogenic genes into human adipose-derived mesenchymal stem cells (AMSCs). A single mesodermal transcription factor, Brachyury, was sufficient to trigger high expression of cardiopoietic markers, Nkx2.5 and Mef2c. Engineered cardiopoietic stem cells (eCP) featured a transcriptome profile distinct from pre-engineered AMSCs. In vitro, eCP demonstrated protective antioxidant capacity with enhanced superoxide dismutase expression and activity; a vasculogenic secretome driving angiogenic tube formation; and macrophage polarizing immunomodulatory properties. In vivo, in a murine model of myocardial infarction, intramyocardial delivery of eCP (600 000 cells per heart) improved cardiac performance and protected against decompensated heart failure. Thus, heart repair competent stem cells, armed with antioxidant, vasculogenic, and immunomodulatory traits, are here engineered through a protein-independent single gene manipulation, expanding the available regenerative toolkit.
Seismic analysis on reinforced concrete group silos through shaking table tests
Authors: Xu Qikeng , Zhang Hao , Liu Qiang , Wang Lumin 
Published: October 2020

AbstractThe main objective of this research is to explore the seismic performance of the group silos through the shaking table tests and the finite element analysis. The 1/16 scaled model of reinforced concrete silos supported by supporting wall was designed and constructed. The shaking table tests were carried out with gradually increasing table‐input acceleration amplitudes. The dynamic characteristics, seismic responses, cracking patterns and failure mechanism of the model under empty and full conditions were analyzed. The finite element model was established and verified by experimental results. This article is aimed to provide guide for engineering design of group silos.
CCR2 downregulation attenuates spinal cord injury by suppressing inflammatory monocytes
Authors: Zhang Qingpu , Zhu Chunjing , Li Xiaojing , Shi Yulin , Zhang Zhongli 
Published: October 2020

AbstractSpecific elimination of blood‐derived macrophages/monocytes following spinal cord injury (SCI) may suppress neurotoxicity without affecting the neuroprotective microglia at the injury sites. We aimed to deplete hematogenous monocytes by downregulating CCR2 through siCCR2‐loaded nanoparticles and investigated its outcome in the recovery of locomotor function of SCI mice. We induced SCI in mice and examined the influx of blood‐derived monocytes into the injury site. We constructed nanoparticles loaded with siRNA targeting CCR2 and examined its efficiency in downregulating the CCR2 expression in cultured RAW264.7 cells and monocytes in vivo. Finally, we assessed the effects of CCR2 downregulation in pro‐inflammatory cytokine production, axon regeneration, and locomotor recovery of the SCI mice. We found that SCI significantly increased the CCL2 expression and number of blood‐derived macrophages/monocytes in the lesion area. Nanoparticles loaded with siCCR2 significantly suppressed the CCR2 expression in hematogenous macrophages/monocytes, reduced the number of hematogenous macrophages/monocytes, and reduced pro‐inflammatory cytokine production at the injury site. Finally, CCR2 downregulation promoted axon regeneration and improved locomotor recovery in SCI mice. Our study suggests that siCCR2 loading nanoparticles are efficient and specific in downregulating hematogenous macrophages/monocytes without affecting the neuroprotective microglia and its efficacy in promoting locomotor recovery in SCI mice warrants further investigation for its clinical application in SCI.
Importance of Depth and Artificial Structure as Predictors of Female Red Snapper Reproductive Parameters
Authors: Brown‐Peterson Nancy J. , Leaf Robert T. , Leontiou Andrea J. 
Published: October 2020

AbstractThe Red Snapper Lutjanus campechanus is a structure‐associated species occurring across a wide depth range in the northern Gulf of Mexico. We used the random forest machine learning algorithm to understand which habitat and individual fish characteristics could predict reproductive parameters of female Red Snapper. We evaluated fish captured from 2016 to 2018 on three artificial structure types with various structure heights at depths of 100 m or less. Overall, we found that depth and month were important predictors for most reproductive parameters, but the type of structure (artificial reefs, oil platforms, and rigs‐to‐reefs structures) was not important. Maturity was correctly classified in 88.9% of the cases when using the random forest ensemble model, with important predictors including FL, depth, structure height, and month of collection. Spawning seasonality (measured as gonadosomatic index [GSI]) was correctly classified in 59.5% of the cases when using histology reproductive phase, FL, month, and depth variables. Reproductively active or inactive females were correctly classified in 89.3% of the cases using GSI, month, FL, and depth, while females in the developing versus spawning capable phases were correctly classified in 82.2% of the cases using GSI, FL, month, and depth. Histological indicators that show potential spawning within a 36‐h period were correctly classified 61.5% of the time, with the best predictors being depth, FL, GSI, and month. Stepwise regression indicated that month was the only factor that significantly predicted contrasts in relative batch fecundity, with significantly greater values in August compared to all other months. Our findings suggest that female Red Snapper reproductive effort is not consistently or well predicted by artificial structure type or height but that a combination of fish FL, month, and depth can predict reproductive characteristics of female Red Snapper.