bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nouvelles de la recherche - 2èmes Journées de la Recherche Filière Piscicole
Authors: PEREZ J.M. 
Published: April 2020

Suite à la première édition de 2007, les organismes de recherche INRA, IFREMER et CIRAD avec le CIPA (Comité Interprofessionnel des Produits de l’Aquaculture), l’ITAVI (Institut Technique de l’Aviculture), le SYSAAF (SYndicat des Sélectionneurs Avicoles et Aquacoles Français) et au Ministère de l’Agriculture et de la Pêche (MAP) ont organisé, en partenariat, les 1 et 2 juillet 2009 les 2èmes Journées Recherche Filière Piscicole (JRFP). Comme pour les autres filières françaises d'élevage, l'objectif de ces journées est d'améliorer les échanges d'informations entre tous les acteurs de la filière. Elles permettent de mieux faire connaître les programmes de recherche, d'en diffuser les résultats et d'en montrer les perspectives d'application ; et de s'informer sur l'évolution des pratiques dans les entreprises.
Durant ces deux journées, plusieurs sessions ont abordé les thèmes d'actualité importants pour la filière piscicole : Nutrition, Environnement, Génétique, Qualité, Durabilité… avec notamment lors de la première journée les réponses et éclairages de la recherche aux grands reproches formulées à la filière : l’Aquaculture pille-t-elle les mers ? l’Aquaculture pollue-t-elle ? Le poisson d’élevage est-il moins bon ?
voir la suite sur le pdf ci-joint https://www6.inrae.fr/productions-animales/content/download/3285/33228/version/1/file/Nouvelle_de_la_recherche-22-5.pdf
Medical career expectations of academically talented high school students: A nationwide cross-sectional study in China
Authors: Wu Hongbin , Pei Leisi , Li Shan , Jiang Cheng 
Published: April 2020

Abstract
Background: Academically talented high school students (ATHSSs), an exceptional cohort, are not well studied for their career expectations, especially for those with medical career expectation (MCE). Nowadays, the public perception of the medical profession is changing in China. The purpose of this study was to answer questions about ‘is medicine attractive for ATHSSs and ‘what factors affect medical career expectations (MCE) for ATHSSs’ in China.Methods: A total of 16,479 representative ATHSSs in senior three completed a questionnaire and four different academic tests. Frequency statistics showed the proportion of ATHSSs with MCE. Unpaired t-tests were performed to find out the differences in demographics, family background, and academic performance between students with and without MCE. The logit models analysis were applied to explore the potential factors that affected the MCE of this exceptional group of students.Results: ATHSSs with MCE accounted for 20.6% (ranking 7/18) of the respondents. They were more likely to be female, came from relatively poorer families, lived in a rural area, and performed significantly worse in all academic tests except for mathematics, compared with those without MCE. In addition, the results revealed that gender (β=-0.436, p<0.01), region of hometown (β=-103, p<0.1), mother’s years of schooling (β=-0.019, p<0.05), and father’s occupational status (β=-0.005, p<0.01) contributed significantly to the MCE of academically talented students. Better performance in mathematics affected the MCE of ATHSSs taking the liberal arts and science tests differently. Conclusions: We found the medical career is becoming unattractive to academically talented students and the medical career may be losing their aura in China. Students who have medical career expectations are likely to be females and to have a weak family background.
Validation of a New Risk Score System for Non-variceal Upper Gastrointestinal Bleeding
Authors: Kim Min Seong , Moon Hee Seok , Kwon In Sun , Park Jae Ho , Kim Ju Seok , Kang Sun Hyung , Sung Jae Kyu , Lee Eaum Seok , Kim Seok Hyun , Lee Byung Seok , Jeong Hyun Yong 
Published: April 2020

Abstract
Background: Recently, a new international bleeding score was developed to predict 30-day hospital mortality in patients with upper gastrointestinal bleeding (UGIB). However, the efficacy of this newly developed scoring system has not been extensively investigated. We aimed to validate a new scoring system for predicting 30-day mortality in patients with non-variceal UGIB and determine whether a higher score is associated with re-bleeding, length of hospital stay, and endoscopic failure.Methods: A retrospective study was performed on 905 patients with acute non-variceal UGIB who were examined in our hospital between January 2013 and December 2017. Baseline characteristics, endoscopic findings, re-bleeding, admission, and mortality were reviewed. The 30-day mortality rate of the new international bleeding risk score was calculated using the receiver operating characteristic curves and compared to the pre-endoscopy Rockall score, AIMS65, Glasgow Blatchford score, and Progetto Nazionale Emorragia Digestiva score. To verify the variable for the 30-day mortality of the new scoring system, we performed multivariate logistic regression using our data and further analyzed the score items.Results: The new international bleeding scoring system showed higher receiver operating characteristic (ROC) curve values in predicting mortality (area under ROC curve 0.958; [95% confidence interval (CI)]), compared with such as AIMS65 (AUROC, 0.832; 95%CI, 0.806-0.856; P<0.001), PNED (AUROC, 0.865; 95%CI, 0.841-0.886; P<0.001), Pre-RS (AUROC, 0.802; 95%CI, 0.774-0.827; P<0.001), and GBS (AUROC, 0.765; 95%CI, 0.736-0.793; P <0.001). Multivariate analysis was performed using our data and showed that the 30-day mortality rate was related to multiple comorbidities, blood urea nitrogen, creatinine, albumin, syncope at first visit, and endoscopic failure within 24 hours during the first admission. In addition, in the high-score group, relatively long hospital stay, re-bleeding, and endoscopic failure were observed.Conclusion: The new international bleeding score could predict 30-day mortality better than the other scoring systems. High-risk patients can be screened using this new scoring system to predict 30-day mortality. The use of this scoring system seems to improve the outcomes of non-variceal UGIB patients through proper management and intervention.
Modified-ramped position: a New Position for Intubation of Obese Females. A Randomized Controlled Pilot Study
Authors: hasanin ahmed , Tarek Hager , Mostafa Maha MA , Arafa Amany , Safina Ahmed G , Elsherbiny Mona H , Hosny Osama , Gado Ahmed A , Almenesey Tarek , Hamden Ghada Adel , Mahmoud Mohamed , Amin Sarah 
Published: April 2020

Abstract
Background : Endotracheal intubation requires optimum position of the head and neck. In obese females, the usual ramped position might not provide adequate intubating conditions. We hypothesized that a new position, termed modified-ramped position, during induction of anesthesia would facilitate endotracheal intubation through bringing the breasts away from the laryngoscope and would also improve the laryngeal visualizationMethods: Sixty obese female patients scheduled for general anesthesia were randomly assigned into either ramped or modified-ramped position during induction of anesthesia. In the ramped position (n=30), the patient head and shoulders were elevated to achieve alignment of the sternal notch and the external auditory meatus; while in the modified-ramped position (n=30), the patient shoulders were elevated using a special pillow, and the head was extended to the most possible range. Our primary outcome was the incidence of failed laryngoscopic insertion in the oral cavity (the need for patient repositioning). Other outcomes included time till vocal cord visualization, time till successful endotracheal intubation, difficulty of the mask ventilation, and Cormack-Lehane grade for laryngeal view.Results: Fourteen patients (47%) in ramped group required repositioning to facilitate introduction of the laryngoscope in the oral cavity in comparison to one patient (3%) in the modified-ramped position (p<0.001). Modified-ramped position showed lower incidence of difficult mask ventilation, shorter time for glottic visualization, and shorter time for endotracheal tube insertion compared to the ramped position. The Cormack-Lehane grade was better in the modified-ramped position. Conclusion: Modified-ramped position provided better intubating conditions, improved the laryngeal view, and eliminated the need for repositioning of obese female patients during insertion of the laryngoscope compared to ramped position.Clinical trial registration:Identifier: NCT03640442Registration URL: https://clinicaltrials.gov/ct2/show/NCT03640442?term=ahmed+hasanin&rank=4Date: August 2018
Model Construction of Medical Endoscope Service Evaluation System-Based on the Analysis of Delphi Method
Authors: Zheng Jun , Lou Ligang , Xie Ying , Chen Siyao , Li Jun , Wei Jingming , Feng Jingyi 
Published: April 2020

Abstract
Background: Medical endoscope is widely used in clinical practice for the purpose of diagnosis and treatment,occupying around 5% of the medical device market. Evaluating the true service level of medical endoscope is essential and necessary to improve overall performance of medical diagnosis and treatment, and to maintain competitiveness of endoscope manufacturers, however, such a tool is not available in the market. This study develops an Evaluation Index System (EIS) to assess service level of medical endoscope, and to provide suggestions for improving the service level through the Delphi method. Methods: Firstly, the possible factors influencing the service level were identified from literature review. In parallel, the Delphi expert method questionnaire was designed and 25 experts were invited to conduct three rounds of questionnaire, to evaluate and rate the possible factors. Finally, we determined the weights associated with the factors, using the analytic hierarchy process (AHP) and percentage method, and developed theservice level EIS. Results: The EIS consists of 3 first-level indicators, 24 second-level indicators and 68 third-level indicators. According to the weights computed using AHP, first-level indicators are ranked as post-sale (0.62), in-sale (0.25) and pre-sale (0.13). Through case verification, the medical endoscope brand Olympus had a total score of 4.17, Shanghai Aohua had a total score of 3.71, and Shanghai Chengyun had a total score of 3.28, which matches its market popularity and ranking in terms of market share. The results obtained from the EIS are consistent with the reality. Conclusions: The EIS established in this study is comprehensive, reliable and reasonable with strong practicality. The EIS can act as a tool for the endoscope users to evaluate potential products and make informed choices. It also provides a measurable basis for endoscope manufacturers and service providers to improve service quality.
Training effect on performance of mediolateral episiotomies for obstetricians and midwives
Authors: Zhao Baihui , Chen Yuan , Xi Fangfang , Dong Tian , Pu Yuqun , Wang Yali , Luo Qiong 
Published: April 2020

Abstract
Background: Simulation as an extensive used method for obstetric education is usually practiced for beginners, here we offered a course with simulated practice of performing a mediolateral episiotomy (MLE) for obstetricians and midwives in different seniority, and to evaluate the training effect on their knowledge and accuracy of cutting a MLE before and after the course.Methods: 82 participants were recruited at three different obstetric centers, included 35 obstetricians and 47 midwives. More than 5 years obstetric work in their careers were deemed to senior ones, and there were 29 junior and 53 senior ones. A 30 minutes training course were given to all participants by one senior obstetrician. Special paper pads simulating perineum at crowning were used to cut MLE before and after the course, and a questionnaire about their occupation characteristics was given before the course. Three parameters of the MLE were analyzed and compared. Results: On performing MLE, midwives had more training history and conducted cases than obstetricians (p < 0.01). After the course, the mean values of three parameters were significantly increased from 31.46 mm in length, 48 degrees in angle and 9.09 mm in distance to 34.29 mm, 50.622 degrees and 10.82 mm respectively. In subgroups, obstetricians had angle degrees increased significantly (p =0.022), while midwives had the length and distance increased significantly (p=0.001, p=0.004). Senior participants had the length and distance of incisions increased significantly (P=0.008, P=0.020), the accuracy of these two parameters also improved significantly (P=0.002, P=0.034). In subgroups of midwives and seniors, the accuracy of the length and distance also improved significantly after the course.Conclusions: Obstetricians need more professional training about midwifery including episiotomy. Simulated training of this mode is suitable for obstetric education like performing MLE. The absence of senior obstetricians and midwives should be avoided in such medical education.
Vertical pons hyperintensity and hot cross bun sign in cerebellar-type multiple system atrophy and spinocerebellar ataxia type 3
Authors: Sugiyama Atsuhiko , Yokota Hajime , Yamanaka Yoshitaka , Mukai Hiroki , Yamamoto Tatsuya , Hirano Shigeki , Koide Kyosuke , Ito Shoichi , Kuwabara Satoshi 
Published: April 2020

Abstract
Background The “hot cross bun” (HCB) sign, a cruciform hyperintensity in the pons on magnetic resonance imaging (MRI), has gradually been identified as a typical finding in multiple system atrophy, cerebellar-type (MSA-C). Few reports have evaluated the sensitivity of an HCB, including a cruciform hyperintensity and vertical line in the pons, which precedes a cruciform hyperintensity, in the early stages of MSA-C. Moreover, the difference in frequency and timing of appearance of an HCB between MSA-C and spinocerebellar ataxia type 3 (SCA3) has not been fully investigated.Methods This study investigated the time at which an HCB and orthostatic hypotension (OH) appeared in 41 patients with MSA-C, based on brain MRI and head-up tilt test. The MRI findings were compared with those of 26 patients with SCA3. The pontine signal findings on T2-weighted MRI were graded as 0 (no change), 1 (a vertical T2 high-intensity line), or 2 (a cruciform T2 high-intensity line), with grades 1 or 2 considered as an HCB. OH 30/15 was defined as a decrease in systolic blood pressure of > 30 mmHg or diastolic blood pressure of > 15 mmHg.Results Among the 24 patients with MSA-C within 2 years from the onset of motor symptoms, an HCB was detected in 91.7%, whereas OH 30/15 was present in 60.0%. Among the 36 patients with MSA-C within 3 years from the onset of motor symptoms, a grade 2 HCB was detected in 66.7% of those with MSA-C but in none of those with SCA-3.Conclusions HCB is a highly sensitive finding for MSA-C, even in the early stages of the disease. A grade 2 HCB in the early stage is an extremely specific finding for differentiating MSA-C from SCA-3.
Self-rated health inequalities in the intersection of gender, social class and regional development in Spain: exploring contributions of material and psychosocial factors
Authors: Barnils Núria Pedrós , Eurenius Eva , Gustafsson Per E 
Published: April 2020

Abstract
Background: Inequalities in health across social class, gender and regional context in Spain are well-known; however, there is a lack of research examining how these dimensions of inequality interact. This study explores self-rated health (SRH) inequalities across intersectional positions of gender, social class and region, and the contribution of material and psychosocial factors to these inequalities. Methods: Participants were drawn from the cross-sectional 2015 National Living Conditions Survey of Spanish residents aged 19-88 years (N=27,215; 77% response rate). Eight intersectional positions were formed by combining dichotomous variables of gender, social class and regional development. Poisson regression was used to estimate intersectional inequalities in SRH as prevalence ratios, and the contributions of material and psychosocial factors. Results: Results showed both cumulative and heterogeneous inequalities within and across intersectional positions. Inequalities in the intersection of social class and regional development were best explained by the joint contributions of material and psychosocial factors, while gender inequalities within non-manual social class were better explained by material factors alone. Conclusions: The results illustrate the complexity of interacting inequalities in health and their underpinnings in Spain. Local and national policies taking this complexity into account are needed to broadly improve equity in health in Spain.
Correlation of Binocular Refractive Errors and Calculation of Intraocular Lens Power for the Second Eye
Authors: Zhang Pengcheng , Yang Yuhuan , Yan Hong , Zhang Jie , Yan Weijia 
Published: April 2020

Abstract
Background: How to reduce the refractive error has always been a tricky problem. The aim of this study was to verify the correlation between binocular refractive errors (RE) after sequential cataract surgery and explore the individualized calculation method of intraocular lens (IOL) for the second eye.Methods: This is a prospective study. One hundred eighty-eight affected eyes of 94 age-related cataract patients with sequential cataract surgery from the Department of Ophthalmology, Tangdu Hospital, china, were recruited. Complete case data of 94 patients were included for correlation analysis of binocular RE. Thereafter, data of patients with RE values greater than 0.50 diopter (D) in the first eyes were extracted and divided randomly into two groups- Group A and B. As the adjustment group, in group A we modified the IOL power for the second eyes according to 50% of the RE of the first eye, and group B was the control group without modify. The mean absolute refractive error (MARE) values of the second eyes were evaluated one month after surgery.Results: The correlation coefficient of binocular RE after sequential cataract surgery was 0.760 (P < 0.001). After the IOL power of the second eyes were adjusted, the MARE of the second eyes was 0.57±0.41 D while MARE of the first eyes was 1.18±0.85 D, and the difference was statistically significant (P<0.001).Conclusions: Binocular REs were correlated positively after sequential cataract surgery. The RE of the second eye can be reduced by adjusting the IOL power based on 50% of the postoperative RE of the first eye.
Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study
Authors: Song Qiaofeng , Liu Xiaoxue , Zhou Wenhua , Wu Shouling , wang xizhu 
Published: April 2020

Abstract
Background To explore the associations between sleep duration and abnormalities in each serum lipid level in a Chinese population. Methods A prospective study was conducted with 34,260 participants from the general Chinese population. Sleep duration was categorized as ≤5, 6, 7, 8 or ≥9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults(2016). The Cox proportional hazards model was used to assess these associations. Results Compared with a seven-hour sleep duration, longer sleep duration was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (HR: 1.24; 95% CI: 1.12–1.38). In subgroup analyses, the positive association between long sleep duration and low HDL-C levels in men and in the different age groups were more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population(p- interaction>0.05). Conclusions These findings suggest that longer sleep duration is associated with low HDL-C levels among the Chinese population.
Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster
Authors: Venugopal Parvathy , Veyssiere Hugo , Couderc Jean-Louis , Richard Graziella , Vachias Caroline , Mirouse Vincent 
Published: April 2020

Abstract
Background : Scaffold proteins support a variety of key processes during animal development. Mutant mouse for the MAGUK protein Discs large 5 (Dlg5) presents a general growth impairment and moderate morphogenetic defects. Results: Here, we generated null mutants for Drosophila Dlg5 and show that it owns similar functions in growth and epithelial architecture. Dlg5 is required for growth at a cell autonomous level in several tissues and at the organism level, affecting cell size and proliferation. Our results are consistent with Dlg5 modulating hippo pathway in the wing disc, including the impact on cell size, a defect that is reproduced by the loss of yorkie. However, other observations indicate that Dlg5 regulates growth by at least another way that may involve Myc protein but nor PI3K neither TOR pathways. Moreover, epithelia cells mutant for Dlg5 also show a reduction of apical domain determinants, though not sufficient to induce a complete loss of cell polarity. Dlg5 is also essential, in the same cells, for the presence at Adherens junctions of N-Cadherin, but not E-Cadherin. Genetic analyses indicate that junction and polarity defects are independent. Conclusions : Together our data show that Dlg5 own several conserved functions that are independent of each other in regulating growth, cell polarity and cell adhesion. Moreover, they reveal a differential regulation of E-cadherin and N-cadherin apical localization.
Radiographic severity index in COVID-19 pneumonia: relationship to age and sex in 783 Italian patients
Authors: Borghesi Andrea , Zigliani Angelo , Masciullo Roberto , Golemi Salvatore , Maculotti Patrizia , Farina Davide , Maroldi Roberto 
Published: April 2020

Abstract
Purpose: To improve the risk stratification of patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an experimental chest X-ray (CXR) scoring system for quantifying lung abnormalities was introduced in our Diagnostic Imaging Department. The purpose of this study was to retrospectively evaluate correlations between the CXR score and the age or sex of Italian patients infected with SARS-CoV-2. Material and Methods: Between March 4, 2020 and March 18, 2020, all CXR reports containing the new scoring system were retrieved. Only hospitalized patients with SARS-CoV-2 infection were enrolled. For each patient, age, sex, and the CXR report containing the highest score were considered for the analysis. Patients were also divided into seven groups according to age. Non-parametric statistical tests were used to examine the relationship between the severity of lung disease and the age or sex.Results: 783 Italian patients (532 males and 251 females) with SARS-CoV-2 infection were enrolled. The CXR score was significantly higher in males than in females only in groups aged 50 to 79 years. A significant correlation was observed between the CXR score and age in both males and females. Males aged 50 years or older and females aged 80 years or older with coronavirus disease 2019 showed the highest CXR score (median ≥ 8).Conclusions: Males aged 50 years or older and females aged 80 years or older showed the highest risk of developing severe lung disease. Our results may help to identify the highest-risk patients and those who require specific treatment strategies.