bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autoimmune progesterone dermatitis in the adolescent population
Authors: Aghazadeh Nessa , Chattha Asma J. , Hartz Martha F. , Davis Dawn Marie R. 
Published: December 2020

AbstractBackground/ObjectiveAutoimmune progesterone dermatitis (APD) is a rare autoimmune hypersensitivity reaction that occurs cyclically at the peak of endogenous progesterone production during the menstrual cycle in women. No study characterizing APD in the adolescent population is found; it appears likely to be underdiagnosed and undertreated.MethodsA retrospective, single‐center, review of all adolescent and pediatric patients (<20 years old at onset) with documented diagnosis of APD.ResultsSeventeen adolescent APD patients were included (mean age at diagnosis: 14.4 ± 2 years, mean interval of 13.6 ± 11.1 months between symptom onset and diagnosis). Twelve patients presented with urticaria, two with fixed drug eruption. Erythema multiforme, eczema, and recurrent aphthous stomatitis were present in one patient each. Exposure to exogenous progestin was present in two patients prior to disease onset. Progesterone skin test was performed in six patients with positive results in two. Fourteen patients received antihistamines and/or a topical corticosteroid. Combined oral contraceptives (COCs) were given to eleven patients, in seven via continuous daily dosing. Gonadotropin‐releasing hormone agonist (GnRHa) was used in five, progesterone desensitization in four, omalizumab in two, and danazol in one patient.ConclusionsAdolescent APD is associated with a significant delay in diagnosis. The most common manifestation is urticaria. Exogenous exposure to progestins is uncommon in adolescent APD. Continuous COC, GnRHa, and progesterone desensitization have been used to control symptoms. Large, multicenter studies are required to better define, diagnose, and treat this under recognized condition among adolescent patients.
The sources of international investment income in emerging market economies
Authors: Joyce Joseph P. 
Published: December 2020

AbstractWe investigate international investment income flows in 26 emerging market countries during the period of 1998–2015. Net investment income registered a deficit for this group of countries of between 2% and 3% of GDP during this period. This deficit has been dominated by payments on foreign direct investment liabilities, which is consistent with the change in the composition of the external liabilities of these countries. Our results indicate that both capital account and trade openness are associated with the deficits on direct investment income. In addition, there was a small deficit in portfolio investment income, which is affected by the development of domestic financial markets and investor protection. Other investments’ income and the income from foreign exchange reserves have a negligible role in total investment income.
The case for starting a new exchange rate after debt settlement: Reexamining alternatives to Argentina’s exchange rate policy in 2001–2002
Authors: Ho Tai‐kuang , Lin Ya‐chi , Yeh Kuo‐chun 
Published: December 2020

AbstractThis research explores the question of which exchange rate regime would bring about better output and price stability, given the initial conditions and the external shocks facing Argentina’s economy in 2001–2002. Our analytical model incorporates a transmission mechanism, the balance‐sheet effects, which formulates the possible interaction between foreign debt and exchange rate policy. We find that a floating exchange rate that depends on external finance outperforms dollarization, after supposing the amount of foreign debt payments is limited. As the relative performance of alternative exchange rate arrangements depends on the foreign debt payments, our empirical results imply that the restructuring of foreign debt should be an integral part of any negotiation concerning the postcrisis exchange rate regime. Our results also show that with the existence of foreign debt, the policy trade‐off implied by the Trilemma becomes much constrained.
Dental infection associated with exuberant gingival necrosis in a patient with paroxysmal nocturnal hemoglobinuria: A case report
Authors: Ximenes Iury da Silva , Filho Osias Vieira de Oliveira , Malta Cássia Emanuella Nóbrega , Dantas Thinalli Sousa , Alves Ana Paula Negreiros Nunes , Mota Mario Rogério Lima , Sousa Fabrício Bitu 
Published: December 2020

AbstractParoxysmal nocturnal hemoglobinuria (PNH) is a hematological disorder that affects hematopoietic stem cells. An association with other hematological diseases, such as hemolytic anemia and neutropenia, is observed with a high occurrence of aplastic anemia. The aim of the present study is to report a case of dental infection in a patient with PNH exhibiting exuberant gingival involvement. A 45‐year‐old male patient sought the Federal University of Ceara reporting severe toothache associated with tooth 24. Clinical examination revealed that the tooth was associated with an apparent fistula and a yellowish lesion with smooth surface located in the palate. The patient had interrupted the medication to control PNH. Blood transfusion was requested due to deficient hematological parameters. Tooth extraction and excisional biopsy were performed under antibiotic coverage. In the postoperative period, low‐level laser therapy (LLLT) was performed. Histopathological examination revealed connective tissue showing extensive necrotic areas, accumulation of basophilic material, numerous cyst‐like cavities, and degenerated cells. Histopathological findings were compatible with the initial clinical diagnosis of gingival necrosis. The patient evolved with febrile neutropenia, requiring hospitalization for 1 month. Improvement in the overall health was observed after the administration of antibiotics, eculizumab, and weekly LLLT at the biopsy site.
Dysphagia in a persistently vegetative patient improved by orthodontic treatment of severe dental misalignment
Authors: Tamura Atsuko , Yamaguchi Kohei , Ariya Chantaramanee , Totoki Hisako , Tohara Haruka 
Published: December 2020

AbstractIntroductionWe describe the treatment of severe dysphagia in a patient left in a persistent vegetative state after an episode of hypoxic‐ischemic encephalopathy following a traffic accident.Case ReportA 38‐year‐old man was in a persistent vegetative state since a traffic accident in 2005, which resulted in cardiopulmonary arrest and hypoxic‐ischemic encephalopathy. His airway had been secured with a tracheostomy, and a gastric tube had been inserted; however, he continued to suffer from urinary tract infections, glossoptosis, and silent aspiration of saliva. Both the maxilla and mandible had very narrow dental arches, with the mandibular incisors exhibiting severe lingual inclination.CourseWe first corrected the dentition in the narrow maxillary arch, followed by the mandibular arch. As the dental alignment improved, tongue movements appeared during oral care, and endoscopy also revealed signs of an active saliva swallowing reflex.DiscussionThe “training approach” generally used to treat severe dysphagia is usually impossible in persistently vegetative patients. In our patient, the tongue movements and saliva swallowing reflex appeared after we expanded the narrow dental arches, suggesting that an orthodontic approach can be effective in such cases. Our findings can be applied to similar cases of vegetative patients to facilitate better oral care and outcomes.
Japanese experiment of a complete and objective automatic grading system of facial signs from selfie pictures: Validation with dermatologists and characterization of changes due to age and sun exposures
Authors: Flament Frederic , Velleman Damien , Yamashita Eri , Nicolas Alexandre , Yokoyama Emilie , Itaya Ayako , Zhang Yuze , Jiang Ruowei , Aarabi Pahram , Abric Aurelie , Nakada Aya , Sagawa Yoko , Nishihara Haruna , Morita Akimichi , Cassier Matthieu , Delaunay Caroline 
Published: December 2020

AbstractObjectiveTo evaluate the capacity of the automatic detection system to accurately grade, from smartphones' selfie pictures, the severity of ten facial signs in Japanese women and their changes due to age and sun exposures.MethodsA three‐step approach was conducted, based on self‐taken selfie images. At first, to check on 310 Japanese women (18‐69 years) enrolled in the northerner Hokkaido area (latitude 43.2°N), how, on ten facial signs, the A.I‐based automatic grading system may correlate with dermatological assessments, taken as reference. Second, to assess and compare age changes in 310 Japanese and 112 Korean women. Third, as these Japanese panelists were recruited according to their usual behavior toward sun exposure, that is, non‐sun‐phobic (NSP, N = 114) and sun‐phobic (SP, N = 196), and through their regular and early use of a photo‐protective product, to characterize the facial photo‐damages.Results(a) On the ten facial signs, detected automatically, nine were found significantly (P < .0001) highly correlated with the evaluations made by three Japanese dermatologists (Wrinkles: r = .75; Sagging: r = .80; Pigmentation: r = .75). (b) The automatic scores showed significant changes with age, by decade, of Wrinkles/Texture, Pigmentation, and Ptosis/Sagging (P < .05). (c) After 45 years, a significantly increased severity of Wrinkles/Texture and Pigmentation was observed in NSP vs. SP women (P < .05). A trend of an increased Ptosis/Sagging (P = .09) was observed.ConclusionThis work illustrates, for the first time through investigations conducted at home, some impacts of aging and sun exposures on facial signs of Japanese women. Results significantly confirm the importance of sun avoidance coupled with photo‐protective measures. In epidemiological studies, the AI‐based system offers a fast, affordable, and confidential approach in detection and quantification of facial signs and their dependence with ages, environments and lifestyles.
Development of a clinical scale to assess the severity of striae distensae
Authors: de Freitas Verena Mony Paes , Miot Hélio Amante , Miot Luciane Donida Bartoli , Nogueira Marcelle Almeida de Sousa , Yarak Samira , Ranulfo Rogerio Tercio , Nunes Gisele Jacobino de Barros , Sanches Jose Antonio , Bagatin Edileia 
Published: December 2020

AbstractBackground and ObjectiveThere is no validated instrument to assess the clinical severity of striae distensae. Here, we aimed to develop a striae distensae severity scale.Material and MethodsAfter a Delphi‐based consensus, 15 items related to striae severity were assessed in 110 areas (breasts, abdomen, and buttocks) from 45 participants. The items were analyzed through a partial least squares model to select the most important variables. To assess the reliability of the scale, 43 areas were retested.ResultsOf the 110 areas evaluated, 34 were breasts, 24 abdomens, and 52 buttocks. Striae were considered mild in 30% of the evaluations, moderate in 33%, severe in 21%, and extremely severe in 16%. The final model was composed by: width of the widest striae, width of the striae with the most frequent pattern, atrophy, number of affected quadrants, distribution (multiple or isolated), hypo or hyperchromia and topography. The scores of the scale demonstrated a high correlation with the clinical classification (rho = 0.77). There was a high agreement in the scores from the reassessed areas (intraclass correlation coefficient = 0.90).ConclusionAn objective and reliable scale to assess the clinical severity of striae distensae on the breasts, abdomen, and buttocks was developed.
Tracking Hispanic Political Emergence in Georgia: An Update
Authors: Hood M.V. , Bullock Charles S. 
Published: December 2020

ObjectiveThis short note traces the political presence of Hispanics in Georgia over the last decade and a half. Our analysis examines Hispanics as a group, as well as comparisons to whites and blacks.MethodsWe rely on official records from the Georgia Secretary of State to produce over time inferences concerning Hispanic voter registration and turnout.ResultsOur findings indicate that Hispanics in Georgia have registered steady gains in registration and turnout since the early 2000s. The share of Hispanics in the Georgia electorate, while just over 2 percent in 2018, is also slowly on the rise. Hispanic political influence is less than the group's share in the population due to the presence of non‐citizens, and registration and turnout rates that continue to lag those for whites and blacks.ConclusionIn the long term, the Hispanic population has the ability to reshape politics in the Peach State. However, given our findings, this process could take years to play out fully.
Establishment of normal reference intervals in dogs using a viscoelastic point‐of‐care coagulation monitor and its comparison with thromboelastography
Authors: Buriko Yekaterina , Drobatz Kenneth , Silverstein Deborah C. 
Published: December 2020

AbstractBackgroundViscoelastic coagulation devices are a useful adjunct to the evaluation of hemostasis in veterinary patients. VCM Vet is a point‐of‐care device that is simple in operation and could be used to diagnose and trend hemostatic abnormalities in sick patients. VCM Vet does not use activators.ObjectivesWe aimed to establish reference intervals (RIs) for VCM Vet in a healthy adult canine population and concurrently perform thromboelastographic (TEG) analysis on these samples with and without tissue factor (TF) activation for RI comparisons.MethodsDuplicate VCM Vet tests were performed immediately upon sample collection. Two concurrent TEG tests were performed on the remaining blood, one citrated, untreated (CU), and one activated with TF at a 1:3600 dilution.ResultsFifty‐two dogs were enrolled in the study. The following RIs were generated for VCM Vet machine 1 and 2, respectively: clot time (CT) (seconds) 163‐480 and 172‐457; clot formation time (CFT) (seconds) 104‐288 and 94‐252, α‐angle (degrees) 41‐65 and 44‐66, and maximum clot firmness (MCF) (no units) 27‐43 and 30‐46. Moderate to good correlations were observed between the two machines with Lin’s concordance correlation coefficients of 0.51‐0.9 and a P < 0.002. TEG RIs were similar to previously reported values.ConclusionsVCM Vet RIs were generated. Each VCM Vet device should have a unique RI established due to inter‐device variability. Direct correlations of VCM Vet values with TEG parameters were not performed due to the narrow range of the normal values and the need to evaluate patients with a wide range of hemostatic abnormalities.
Presumed cancer‐associated retinopathy (CAR) mimicking Sudden Acquired Retinal Degeneration Syndrome (SARDS) in canines
Authors: Grozdanic Sinisa D. , Lazic Tatjana , Kecova Helga , Mohan Kabhilan , Adamus Grazyna , Kuehn Markus H. 
Published: December 2020

AbstractObjectiveTo describe functional and structural features of presumed cancer‐associated retinopathy (CAR) mimicking sudden acquired retinal degeneration syndrome (SARDS) in dogs and describe treatment outcomes.AnimalsSubjects were 17 dogs from 8 eight US states and Canada diagnosed with SARDS or immune‐mediated retinitis (IMR) by 12 ophthalmologists. Nine eyes from seven deceased patients were used for microarray (MA), histology, or immunohistochemical (IHC) analysis.ProceduresDogs underwent complete ophthalmic examination, including retinal photography, optical coherence tomography (OCT), chromatic pupil light reflex testing (cPLR), and electroretinography (ERG), in addition to complete systemic examination. Histology, microarray, and IHC analysis were performed in CAR retinas to evaluate histological and molecular changes in retinal tissue.ResultsNone of the patients evaluated satisfied previously established criteria for diagnosis of SARDS (flat ERG+ no red – good blue PLR), and all were diagnosed with IMR. All patients were diagnosed with a cancer: meningioma (24%), sarcoma (18%), pituitary tumor (12%), and squamous cell carcinoma (12%), other (34%). Median survival time was 6 months from diagnosis (range 1‐36 months). Most frequent systemic abnormalities were as follows: proteinuria (78%); elevated liver enzymes (47%); and metabolic changes (PU/PD, polyphagia – 24%). Immunosuppressive therapy resulted in the reversal of blindness in 44% of treated patients, with 61% of all treated patients recovering and/or maintaining vision. Median time for preservation of vision was 5 months (range 1‐35 months).ConclusionsObserved changes are highly suggestive of immune‐mediated damage in IMR‐CAR eyes. A relatively high percentage of patients with CAR responded positively to immunosuppressive therapy.
Mitogenomic phylogeny of bee families confirms the basal position and monophyly of Melittidae
Authors: Husemann Martin , Neiber Marco Thomas , Nickel Jana , Reinbold Carla V. M. , Kuhlmann Michael , Cordellier Mathilde 
Published: December 2020

AbstractBees (Anthophila) represent a critical taxon for the ecosystem service of pollination and hence have received great scientific attention. The more than 20,000 known species of bees are grouped in seven families. Yet, the relationships between bee families are not entirely clear, and specifically, the position of Melittidae and their monophyly has been discussed in the past. Here, we present the most comprehensive mitogenomic phylogeny of bees including five members of Melittidae from two subfamilies and three tribes. Our results suggest monophyly of the family Melittidae and further support their basal position. The data also support the two subfamilies, but are not in line with current assignment of tribes. Our results show, despite advancement with transcriptomic and whole genomic data, the value of mitochondrial data for the reconstruction of phylogenies.
Invasive and non-invasive acupuncture techniques for pain management in neonates: a systematic review
Authors: Stadler Jasmin , Raith Wolfgang , Mileder Lukas P. , Schmölzer Georg M. , Urlesberger Berndt 
Published: December 2020

Background: Neonatal pain is an extensive research field and there are many possibilities to treat pain in neonates. Acupuncture is one new and non-pharmacological option and a promising tool to reduce pain in neonates undergoing minor painful interventions during routine medical care. Objectives: This review summarises trials of acupuncture for pain reduction in neonates undergoing painful interventions during routine medical care. Data source: MEDLINE, Embase, CINAHL, electronic clinical trials registry platforms and reference lists were systematically screened for trials from their dates of inception to February 2017 (English language database search). Study selection: Inclusion criteria were (1) preterm or term neonates, (2) acupuncture for painful medical interventions and (3) formal pain assessment as a primary or secondary study outcome. We included only randomised controlled trials. Data extraction: Data were extracted using a standardised protocol and individual risk of bias was assessed. Results: The literature search revealed a total of 12 196 records. After application of inclusion criteria, five studies were included in this review. Two studies demonstrated significant pain reduction, one found equal outcomes in comparison to standard care, and two showed significantly higher pain scores with acupuncture alone. Limitations: The main limitation of the results is the heterogeneity across trials in acupuncture modality, acupuncture point selection, control groups and pain assessment (heterogeneity: I2=87%). Conclusion: The results of this review suggest that acupuncture may have a positive pain-relieving effect in neonates. However, due to the low number of available high-quality trials and heterogeneity across the studies it is not possible to state clear recommendations.
Cosmic-ray antiprotons in the AMS-02 era: A sensitive probe of dark matter
Authors: Heisig Jan 
Published: December 2020

Cosmic-ray antiprotons are a powerful tool for astroparticle physics. While the bulk of measured antiprotons is consistent with a secondary origin, the precise data of the AMS-02 experiment provides us with encouraging prospects to search for a subdominant primary component, e.g. from dark matter. In this brief review, we discuss recent limits on heavy dark matter as well as a tentative signal from annihilation of dark matter with a mass [Formula: see text][Formula: see text]100 GeV. We emphasize the special role of systematic errors that can affect the signal. In particular, we discuss recent progress in the modeling of secondary production cross-sections and correlated errors in the AMS-02 data, the dominant ones originating from uncertainties in the cross-sections for cosmic-ray absorption in the detector.
La storiografia medica nell'età della Rivoluzione : l'esperienza francese e italiana
Authors: Bonuzzi di Luciano 
Published: December 2020

Dopo un breve cenno alia storia della storiograjia medica da fppocrate alVeta della grande Rivoluzione, si confrontono i contributi italiani efrancesi editi alia fine del ’700.
Nel ’700 la storia della medicina segue indirizzi annalistici, bibliografici e metodologici. In Francia, con Pinel e Cabanis, la storia della medicina ha soprattutto carattere metodologico come aveva insegnato Cullen. Anche in Italia, dove rinteresse per la disciplina è più tardivo rispetto agli altri paesi europei, si impone il modello metodologico trasmesso dalla cultura di lingua francese.
Playing with Practice Theory: Preliminary Remarks on the Work of Performance Ecologies in 21st Century Bangkok
Authors: Skar Lowell 
Published: December 2020

Abstract
This article builds a framework for considering the place of contemporary performance groups in 21st century Bangkok. It grounds performance groups in ensembles of performance practices developed by groups as part of their unique performance cultures. The varied ensembles of performance practice of three such groups – the Pichet Klunchun Dance Company, the 8X8 Theatre Group, and the B-Floor Artist Collective – are embodied in these groups’ distinctive interactive performance styles and tied to the different creative spaces where they work. The groups’ artistic practices and their working spaces are produced within larger ecologies of performance spanning the urban landscape of 21st century Bangkok. The article suggests this framework as a richer way to study performance cultures in Thailand. Relating the performance landscape of Bangkok’s contemporary theatre scene to the embodied artistic practices of different groups shows how their unique performance cultures help to enliven the city’s distinctive cultural ecology of performance.