bluuebunny/crossref_metadata_2025_split huggingface dataset:
First National Data Reporting Nursing Home Social Services Directors’ Training Interests and Needs
Authors: Bern-Klug Mercedes , Cordes Elizabeth 
Published: December 2020

Abstract
A national sample of 924 social services directors reported training needs in three ways. First, their level of interest in 14 topics, second by how much preparation time needed to provide one-on-one training to a colleague about 27 difference issues/tasks (no time needed, up to 2 hours, up to 10 hours, not able to do), and third, by indicating their top training priority. At least 2/3s reported interest in each of the 14 topics with 86% interested in common mental health and psychosocial challenges, and 86% in the psychosocial needs of persons with dementia. Education, social work licensure, and characteristics of the nursing home explained some of the variation, e.g. respondents with a social work degree reported higher interest in more training in trauma-informed care and culturally competent care. Dementia was by far the highest training priority, followed by better understanding of regulations, behavioral health issues, and trauma-informed care.
The Connection of Social Services to Care Transitions and Discharge Planning in Nursing Home Settings
Authors: Galambos Colleen , Rollin Laura , Engelbart Eric 
Published: December 2020

Abstract
Care transitions are critical junctures in the healthcare delivery process. Effective transitions and discharge planning reduce the need for subsequent transfers between healthcare settings (Boutwell et al., 2015). Understanding social services (SS) involvement in these processes is important due to its key role in their success (Fabbre et al., 2011). Facility characteristics from 924 nursing homes were evaluated in relation to SS involvement in care transitions and discharge planning. Chi-square tests indicate associations between SS involvement and level of engagement of SS expertise by the nursing home administrator (p=.004), medical director (p=.002), nursing staff (p=.003), community physicians (p=.049), and family members (p&lt;.001). An association between SS involvement and freestanding SS departments was also observed. Results suggest the level of SS involvement in care transitions and discharge planning relates to structural (i.e. SS positioning within the facility) and relational (i.e. perceptions and utilization of SS designees by key facility leadership) factors.
CDC Healthy Brain Initiative Action Institutes: Innovative Planning and Lessons Learned
Authors: Holt Heidi 
Published: December 2020

Abstract
This presentation will demonstrate an innovative strategic planning effort, coined Action Institutes (AI’s), which are designed to promote the implementation of CDC’s “The Healthy Brain Initiative’s State and Local Public Health Partnerships to Address Dementia” and the “Road Map for Indian Country.” Both of these documents outline how the champions of public health and their partners can create a statewide effort to promote brain health, increase early diagnosis, address cognitive impairment for individuals living in the community, and help meet the needs of care partners. The purpose of these 1-2-day AI’s is to familiarize leaders with the topic, encourage their adoption into current priority setting, and guide participants in creating action plans. The CDC’s Alzheimer’s Disease and Healthy Aging Program is conducting a series of these AIs, which are made possible through partnerships with the Association of State and Territorial Health Officials and the National Indian Health Board.
The Elder Justice Coalition and Reauthorizing the Elder Justice Act
Authors: Blancato Robert 
Published: December 2020

Abstract
The presentation and dialogue will focus on the elder justice advocacy community and their work to secure reauthorization of the Elder Justice Act, which was originally passed as part of the ACA. Both grassroots and DC-based efforts have been employed to move this and other legislation forward and to secure much needed funding for the programs designed to end elder abuse.
Interest in Supportive Services Among Black Working and Non-Working Caregivers in the Deep South
Authors: Clay Olivio , Epps Fayron , Scott Cathy , Cothran Fawn , Williams Ishan 
Published: December 2020

Abstract
The current investigation provides information on supportive services caregivers said they would be interested in if they were made available. Participants were recruited from the Birmingham, AL metro area and received a $25 gift card for completing a telephone interview. Of the 38 caregivers enrolled, 18 (47.37%) reported being currently employed and working an average of 33.92 hours per week (range = 5 – 60). Participants were caring for individuals with average scores on the AD8 Dementia Screening Scale of 7.3 and 10.4 on the Clinical Dementia Scale Sum of Boxes (above the cutoffs for probable dementia). Thirty-three caregivers (87%) reported being interested in at least one of the services listed with differences observed for services that would be preferred by working vs. non-working caregivers. These data will be utilized to provide initial support for a multicomponent intervention that may be effective in reducing negative outcomes within Black caregivers.
Looking Ahead: Intersecting Influences on Older Gay Men Living With HIV
Authors: de Vries Brian , Gutman Gloria , Sussman Tamara , Brotman Shari , Dube Denis 
Published: December 2020

Abstract
Older HIV-positive gay men live at the intersection of multiple inequalities—with cascading effects on their present and future lives. This qualitative study explored how they plan for their future, with a focus on Advance Care Planning—the process of reflecting/communicating preferences and values for future health and end-of-life care. Seven French-speaking gay men aged 55+ in Montreal, Canada participated in a focus group that was audio-recorded, transcribed and thematically analyzed in four steps. Findings suggest the intersection of sexual orientation and HIV-positive status exacerbated self-disclosure issues; the further addition of age led to preoccupation with day-to-day living and rendered these men vulnerable to social isolation. These tensions not only interfered with their capacities to talk about future care, but also created barriers to thinking about future care. These findings describe the multiple layers and compounding consequences of inequality among older gay men living with HIV.
Socioeconomic Inequalities in Informal Care Provision and Its Consequences for Well-Being Across Europe
Authors: Quashie Nekehia , Kaschowitz Judith , Deindl Christian , Brandt Martina 
Published: December 2020

Abstract
We assess socioeconomic inequalities in informal care provision and its consequences for the wellbeing of informal caregivers. The literature states that a lower socio economic status (SES) is linked to a higher probability to give care (at higher intensities) which then leads to a higher caregiving burden. People with lower SES additionally have fewer resources to alleviate caregiving pressures. Thus, they are likely to experience decreased wellbeing compared to those with higher SES. Our analyses based on data from SHARE and ELSA confirm, that individuals with lower SES are indeed more likely to provide care all over Europe. They also report a lower wellbeing than people with higher SES, even if controlling for further important influences. In the next step we investigate longitudinally, if taking over care responsibilities leads to a wellbeing decline and if this decline is more pronounced for people with lower SES.
Transforming Gerontological Research by Meaningfully Engaging Persons Living With Dementia
Authors: Lepore Michael , Fortinsky Richard 
Published: December 2020

Abstract
Whereas persons living with dementia have commonly been subjects of gerontological research, participation of persons with dementia in designing and conducting studies and in scientific research meetings has been rare in the United States. In recent years, person-centered research models have arisen which give persons with dementia and their caregivers core roles in the research enterprise. As “co-researchers” with academic/professional researchers, persons with dementia and their caregivers are engaged in all aspects of the research enterprise, jointly developing research questions and study designs, collecting and analyzing data, planning research meetings, and disseminating results. International studies have shown that conducting research in collaboration with the population that is being studied has potential to enhance the quality and appropriateness of research and has been identified as an essential component of studies examining the effectiveness of different approaches to care. This session spotlights innovative advances in gerontological research that meaningfully engages persons with dementia. First, the engagement of persons with dementia in scientific meetings is addressed drawing on the examples of the 2017 and 2020 National Research Summits on Care Services and Supports for Persons with Dementia and their Caregivers (i.e., Summits). Next, a study using a patient engagement framework for caregivers and individuals with mild cognitive impairment living at home is discussed. Finally, the Empowering Partnerships program, which prepares researchers, persons with dementia, and care partners to collaborate in conducting research is reviewed. Outcomes and challenges of these innovations are examined, and the need for academic/professional researcher roles to evolve is discussed.
Saint Louis University Primary Care Age-Friendly Health System Initiative in Rural and Urban Communities
Authors: Berg-Weger Marla , Morley John 
Published: December 2020

Abstract
The Saint Louis University GWEP partners with a rural Missouri critical access hospital and an urban Federally Qualified Health Center to support their transformations into an Age-Friendly Health System in their community. With an emphasis on the 4Ms, programmatic innovations include development and training of: 1) electronic health records integration of the Rapid Geriatric Assessment (RGA) for patients 65+ years old; 2) RGA-based protocol for Medicare Annual Wellness Visits (MAWV); 3) Interprofessional health care team approach; 4) Evidence-based or Evidence-Informed treatment interventions, including Cognitive Stimulation Therapy (CST), exercise and strengthening program, caregiver support, and Circle of Friends, an intervention for loneliness and social isolation. Outcomes will be presented which suggest increased assessment practices and improvement in functional and cognitive status. Successes and lessons learned regarding strategies to develop an Age-Friendly Health System in two different primary care settings will be discussed.
Connecting Generations in Senior Housing: Promising Practices and Challenges
Authors: Henkin Nancy 
Published: December 2020

Abstract
Senior housing can be an ideal platform for high quality intergenerational programming. Often older adults who move to congregate housing settings experience feelings of loneliness and a loss of purpose. Creating long term partnerships with educational and youth-serving organizations can help senior housing providers expand residents’ social networks and create meaningful civic engagement opportunities. A 3-year national initiative involving an environmental scan of intergenerational practice in senior housing communities, the development of a toolkit for senior housing providers, and the piloting of intergenerational partnerships and programs in six national housing communities was conducted by Generations United and Leading Age and supported by the Retirement Research Foundation. Promising practices, challenges, and lessons learned from this initiative will be shared and strategies for “scaling” this work will be discussed.
Historical and Generational Forces and Gender Differences in the Iridescent Life Course of Transgender Older Adults
Authors: Emlet Charles , Goldsen Karen Fredriksen , Fabbre Vanessa , Jung Hailey , Kim Hyun 
Published: December 2020

Abstract
Shifting historical, political, and social times have impacted transgender older adults in experiences and development. Examining how gender identities interact with life events within a historical context elucidates differences by generations and gender. Using a transgender subsample (n=205) from the National Health, Aging, and Sexuality/Gender Study (N=2,450), (logistic) weighted regressions with sociodemographic adjustment were performed to examine generational differences and gender interaction in key life experiences in identity, work, kin, bias, community, and health/well-being. Silenced (born 1935-1949, 18%), than Pride (1950-1964, 79%), Generation disclosed identity later, is less visible, more likely retired and veteran, more likely for lifetime opposite-sex marriage and divorce. Significant gender interactions exist in community engagement, kin relationships, and physical health. Despite small sample size, Invisible Generation (1914-1934, 3%) has unique differences. Findings show complexity of generational differences among transgender older adults, understanding of what helps better serve them as they age with their accumulated life experiences.
Microbiome: Living Well and Thriving With Your Bacteria
Authors: Wang Meng , Ludington William 
Published: December 2020

Abstract
This symposium aims to invite speakers who are the leading experts in the field of microbiome and longevity, and select short talks from abstracts submitted by young investigators, postdoctoral fellows and graduate students. We will discuss new progress in this exciting research area and raise new questions for future studies. Confirmed speakers include Evgeny Nudler from NYU, Will Ludington from Carnegie, Paul O’Toole from University College Cork, Ireland, and Meng Wang from Baylor College of Medicine.
Microbiome-Mitochondria Communication in the Regulation of Host Longevity
Authors: Wang Meng 
Published: December 2020

Abstract
Mitochondria are ancient relatives of bacteria in eukaryotic cells and dynamically interconnected through organelle fusion and fission. Given the close relationship between bacteria and eukaryotic mitochondria during evolution, my group is interested in understanding the critical role of their communication in regulating host’s longevity. We have conducted genome-scale screens to decipher how bacterial genetic composition impacts host longevity, leading to the discovery of specific bacteria-secreted metabolites that fine-tune the mitochondrial fusion-fission balance and consequently promotes longevity across different host species. We have further developed optogenetic approaches to manipulate bacterial gene expression and metabolite production inside the gut of live organisms, in order to investigate the microbiome-mitochondria communication in time and space. Our studies demonstrate a novel mode of signaling communication between bacteria and mitochondria, reveal its vital impacts on host healthy aging, and provide new methods to decipher the spatiotemporal relationship between the microbiome and the host.
Stem Cells, Diet, and Physiology
Authors: Drummond-Barbosa Daniela 
Published: December 2020

Abstract
Nutrient availability, stresses, and aging affect tissue stem cells in multicellular organisms; yet, the underlying physiological mechanisms in vivo remains largely unexplored. Dr. Drummond-Barbosa pioneered using Drosophila to study the physiology of tissue stem cell regulation. Her laboratory played a major role in delineating how diet, brain insulin-like peptides, and the TOR nutrient sensor control the germline stem cell (GSC) lineage. They also discovered that adipocyte-specific disruption of amino acid transport, other nutrient signaling, and metabolic pathways causes distinct germline phenotypes. They also showed that nuclear receptors act in multiple tissues to affect the GSC lineage through direct and indirect mechanisms. More recently, her group has been exploring how other physiological stresses affect the GSC lineage. Her group’s studies point to extensive communication between the brain, adipocytes, hepatocyte-like cells, and the germline, and underscore the complexity of the physiological network that modulates stem cell lineage behavior.
Aging germline stem cells in C. elegans
Authors: Hubbard E Jane 
Published: December 2020

Abstract
Failure to maintain stem cells with age is associated with conditions such as tissue degeneration and increased susceptibility to tissue damage. We use the C. elegans germline stem cell system as a model to study stem cell aging. This system combines a well-established model for aging with an accessible stem cell system, providing a unique opportunity to understand how aging influences stem cell dynamics. The germline stem/progenitor pool in in C. elegans becomes depleted over time. At the cellular level, aging influences both the size of the stem cell pool and the proliferation rate of stem cells. The flux of differentiated cells also affects how aging impacts the pool. This depletion is partially alleviated in mutants with reduced insulin/IGF-like signaling via inhibition of the transcription factor DAF-16/FOXO. In this role, DAF-16 does not act in the germ line, and its anatomical requirements are different from its previously described roles in larval germline proliferation, dauer control, and lifespan regulation. We found that DAF-16/FOXO is required in certain somatic cells in the proximal part of the reproductive system to regulate the stem cell pool. We also find that the degree to which various age-defying perturbations affect lifespan does not correlate with their effect on germline stem cell maintenance. We are investigating additional aspects of aging germline stem cells using this system.
Genetic, Epigenetic, and Metabolic Maintenance of Neural Stem Cells During Aging
Authors: Webb Ashley 
Published: December 2020

Abstract
Tight metabolic regulation is essential to maintain stem cell homeostasis and support healthy aging. With age, metabolic alterations cause neural stem cell (NSC) dysfunction and are associated with a decline in neurogenesis, but the underlying mechanisms are not known. Aged stem cells display defects in the autophagy-lysosomal pathway that may disrupt mitochondrial dynamics, resulting in metabolic disruptions that alter self-renewal and differentiation potential. We have used genomic and functional approaches to investigate the metabolic mechanisms that support NSCs throughout aging. We found that mitochondrial and mitophagy gene networks as well as mitophagy dynamics are differentially regulated between the quiescent and activated states and become dysregulated with age. This work provides new insight into the metabolic regulation of NSCs and may lead to strategies to enhance neurogenesis in the context of aging and neurodegenerative disease.
Model Organisms: Grandeur in the Diversity of Aging Organisms
Authors: Brunet Anne 
Published: December 2020

Abstract
Aging is a complex process that converts vigorous and healthy individuals into frail and decrepit ones, with increased susceptibility to a constellation of diseases. Human aging is influenced by many factors, including genetics, environment, lifestyle, sex, and socio-economic status. While aspects of aging can be studied directly in humans, discovering the causative factors that modulate this process often requires interventions and modeling. Traditional models will likely continue to provide a wealth of translatable information. Studying ‘extremophiles’ has exciting potential for providing new concepts that could be implemented for lifespan regulation. The development of new experimental models uniquely tailored to aging studies is also an essential step. This symposium will discuss African killifish, planarian, naked mole rats, and domestic dogs as new models for aging and exceptional longevity and rejuvenation. The iteration between new models and humans could be particularly helpful in delineating strategies to promote healthy aging and extend the disease-free portion of life.
High-Risk Medication Use and Polypharmacy in Older Veterans Who Attempt Suicide
Authors: Morin Ruth , Li Yixia , Steinman Michael , Wiechers Ilse , Byers Amy 
Published: December 2020

Abstract
Late-life veteran suicide is a public health concern, and may overlap with recent high-risk medication use. We identified use in the 6 months prior to attempt and assessed salient risk factors. 13,872 veterans aged 50 years and older that attempted suicide were compared with demographically-matched controls utilizing VHA healthcare in a similar time period. Medications potentially related to suicide risk were included. Other variables were psychiatric and medical diagnoses, fatality of attempt and means. Compared with controls, veterans who attempted were nearly 3 times more likely to have been prescribed benzodiazepines and opioids, even when controlling for other diagnoses. Those taking 3 or more high-risk medications were between 7 and 11 times more likely to attempt than controls, with a higher risk of death particularly by drug overdose. These findings begin to uncover the complex contribution of prescription medications and polypharmacy to late-life veteran suicide, with implications for prevention. Part of a symposium sponsored by the Aging, Alcohol and Addictions Interest Group.
Associations Between Aging-Related Biomarkers, Interstitial Lung Abnormalities, and Mortality
Authors: Sanders Jason 
Published: December 2020

Abstract
Interstitial lung abnormalities (ILA) exist in ~10% of adults &gt;50 and associate with increased morbidity/mortality. Their pathobiology is poorly understood; age is the strongest risk factor. In the Framingham Heart Study, we determined associations between ILA and 10 blood biomarkers previously robustly associated with aging and mortality. Odds of ILA increased directly with ln-transformed GDF15 (OR [95% CI] = 3.20 [1.74-5.91], p=0.0002), TNF-αRII (2.41 [1.34-4.34], p=0.003), IL6 (1.76 [1.39-2.22], p&lt;0.0001), insulin (1.56 [1.11-2.20], p=0.01), and CRP (1.53 [1.27-1.84], p&lt;0.0001). Causal analysis showed GDF15 (p=0.008), TNF-αRII (p=0.004), and IL6 (p&lt;0.0001) mediate the age effect on ILA. In adjusted survival models, only higher ln(GDF15) and ln(TNF-αRII) were associated with mortality (HR [95% CI] = 4.3 [2.3-8.1], p&lt;0.0001 and 2.9 [1.5-5.8], p=0.002). GDF15 results were replicated in the COPDGene Study. These results suggest aging biomarkers may help risk stratify adults with ILA, and unmeasured ILA may confound prior associations between biomarkers and mortality.
Energy Sensing Pathways in Aging and Chronic Lung Disease
Authors: Thannickal Victor 
Published: December 2020

Abstract
The cause-effect relationships between the various “hallmarks of aging” and chronic lung disease are not well understood. We have determined overlapping pathways involving deregulated nutrient sensing, mitochondrial dysfunction, and cellular senescence that may contribute to the evolution of chronic lung disease. In particular, I will discuss alterations in energy/metabolic sensing pathways and mitochondrial dysfunction as pathobiological mechanisms that may explain the age-related increased susceptibility to the development and progression of idiopathic pulmonary fibrosis (IPF), a disease of pulmonary aging. I will then broaden the discussion to include the potential role of these biologic alterations in other chronic lung disease which burden older adults.