bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of pregnancy and delivery in women with Kawasaki disease and residual coronary artery lesion with detailed analysis of labor analgesia: combined experience of 13 cases in two institutions
Authors: Inoue Rie , Mazda Yusuke , Tanaka Hiroaki , Tanaka Kayo , Yoshimatsu Jun , Tamura Kazumi , Terui Katsuo 
Published: September 2020

Abstract
Introduction
Approximately half of Kawasaki disease patients are expected to have transitioned to adulthood, and an increasing number of patients with cardiovascular sequelae have gotten pregnant. Management of women with Kawasaki disease who have residual coronary artery disease is poorly established. Thus, we conducted detailed analysis of these cases.

Methods
We reviewed 19 pregnancies in 13 such women in two tertiary perinatal facilities, Saitama Medical Center and National Cardiovascular Center. The medical records were reviewed in all women with Kawasaki disease and coronary artery lesion between 1998 and 2015, with regard to age of diagnosis, types of coronary artery lesion, location, previous treatment, pregnancy course and medical management for coronary lesion, cardiac function, and planned mode of delivery.

Results
Fourteen parturients attempted vaginal delivery, and all but one received neuraxial analgesia, providing stable hemodynamics. Four elective and two emergency cesarean deliveries were performed due to obstetric indications, while one woman required cesarean delivery at preterm due to maternal cardiac indication.
Among 14 attempted vaginal deliveries, instrumental vaginal delivery was performed in 50%. Cardiac events were noted in four women, all in post-partum period, such as non-sustained ventricular tachycardia or chest discomfort without ECG changes. Antithrombotic medication was exclusively low dose aspirin in 11 of 19 pregnancies (58%), and none received anticoagulation during pregnancy or delivery.

Conclusion
Our case series support the practice of preferred vaginal delivery, with neuraxial labor analgesia in indicated patients, while highlighting the need for vigilance in the post-partum period.
Assessment of flow pattern of right ventricle outflow and pulmonary arteries in surgically corrected tetralogy of Fallot patients by four-dimensional cardiac magnetic resonance flow
Authors: Shaaban Mahmoud , Salama Mai , Alsaied Ayman , Elsheikh Raghda , Elmasry Magdy 
Published: September 2020

Abstract
Background
The most common post-surgical complication of tetralogy of Fallot (TOF) is pulmonary regurgitation (PR) which can lead to right ventricle (RV) dysfunction/failure. Cardiac magnetic resonance (CMR) is the imaging modality of choice to follow-up a repaired TOF. However, the conventional two-dimensional phase-contrast (2D-PC) flow usually underestimates PR as well as the pulmonary peak systolic velocity (PSV). Recently, four-dimensional (4D) CMR flow is introduced for more accurate quantitative flow assessment. This work aimed to compare between 4D-CMR and 2D-PC flow across the main (MPA), right (RPA), and left (LPA) pulmonary arteries (PAs) in surgically corrected TOF patients.

Results
This study was conducted on 20 repaired TOF patients (range 3–9 years, 50% males). All patients had CMR exam on 1.5T scanner. 4D-CMR and 2D-PC flows were obtained at the proximal segments of the MPA, RPA, and LPA. The stroke volume index (SVI), regurgitation fraction (RF), and PSV measured by 4D-CMR were compared to 2D-PC flow. The SVI across the PAs was nearly similar between both methods (P = 0.179 for MPA, 0.218 for RPA, and 0.091 for LPA). However, the RF was significantly higher by 4D-CMR in comparison to 2D-PC flow (P = 0.027 for MPA, 0.039 for RPA, and 0.046 for LPA). The PSV as well was significantly higher by 4D-CMR flow (P = 0.003 for MPA, < 0.001 for RPA, and 0.002 for LPA). The Bland-Altman plots showed a good agreement between 4D-CMR and 2D-PC flow for the SVI, RF, and PSV across the pulmonary arteries.

Conclusion
A good agreement existed between the two studied methods regarding pulmonary flow measurements. Because of its major advantage of performing a comprehensive flow assessment in a shorter time, 4D-CMR flow plays an important role in the assessment of patients with complex CHD especially in the pediatric group.
An introduction to the assessment and management of psychodermatological disorders
Authors: Gibson Russell , Williams Penny , Hancock Jason 
Published: September 2020

SUMMARYPsychodermatology is an emerging field at the interface between psychiatry, psychology and dermatology. There is a strong bidirectional relationship between a number of dermatological disorders and psychiatric disorders. This article provides an overview of psychiatric disorders with dermatological symptoms, and dermatological disorders with secondary psychophysiological consequences. The principles of management and our insights into establishing a psychodermatology service in the UK are discussed.
Overlap between attention-deficit hyperactivity disorder and neurodevelopmental, externalising and internalising disorders: separating unique from general psychopathology effects
Authors: Du Rietz Ebba , Pettersson Erik , Brikell Isabell , Ghirardi Laura , Chen Qi , Hartman Catharina , Lichtenstein Paul , Larsson Henrik , Kuja-Halkola Ralf 
Published: September 2020

BackgroundAlthough attention-deficit hyperactivity disorder (ADHD) is classified as a neurodevelopmental disorder in the latest diagnostic manuals, it shows phenotypic and genetic associations of similar magnitudes across neurodevelopmental, externalising and internalising disorders.AimsTo investigate if ADHD is aetiologically more closely related to neurodevelopmental than externalising or internalising disorder clusters, after accounting for a general psychopathology factor.MethodFull and maternal half-sibling pairs (N = 774 416), born between 1980 and 1995, were identified from the Swedish Medical Birth and Multi-Generation Registers, and ICD diagnoses were obtained from the Swedish National Patient Register. A higher-order confirmatory factor analytic model was fitted to examine associations between ADHD and a general psychopathology factor, as well as a neurodevelopmental, externalising and internalising subfactor. Quantitative genetic modelling was performed to estimate the extent to which genetic, shared and non-shared environmental effects influenced the associations with ADHD.ResultsADHD was significantly and strongly associated with all three factors (r = 0.67–0.75). However, after controlling for a general psychopathology factor, only the association between ADHD and the neurodevelopmental-specific factor remained moderately strong (r = 0.43, 95% CI = 0.42–0.45) and was almost entirely influenced by genetic effects. In contrast, the association between ADHD and the externalising-specific factor was smaller (r = 0.25, 95% CI = 0.24–0.27), and largely influenced by non-shared environmental effects. There remained no internalising-specific factor after accounting for a general factor.ConclusionsFindings suggest that ADHD comorbidity is largely explained by genetically influenced general psychopathology, but the strong link between ADHD and other neurodevelopmental disorders is also substantially driven by unique genetic influences.
Emotional abuse and neglect: time to focus on prevention and mental health consequences
Authors: Kumari Veena 
Published: September 2020

SummaryEmotional abuse and emotional neglect are among the most prevalent of childhood maltreatment types and associated with a range of poor mental health outcomes. We need to move beyond correlational research and shift our focus to sophisticated multimodal studies to fully understand the psychobiological mechanisms underlying these associations and to intervention studies.
Gastrointestinal system
Authors: Pogson Rachel 
Published: September 2020

The clinical examination is an important part of any patient consultation. After the primary survey and taking the patient history, a more in-depth examination is sometimes required to aid making a working diagnosis and help negate other differential diagnoses. The extent of this depends on the stability of the patient and may not be possible in time-critical circumstances. However, clinical examination is an increasing part of paramedic practice owing to the continued expansion of the scope of the paramedic role in both urgent and emergency care. Education on clinical examination concerning each of the main body systems is now an integral part of undergraduate paramedic curricula.This clinical examination series provides a step-by-step overview for each of the main body systems. Continuing professional development (CPD) is an essential requirement for all clinicians to maintain and to demonstrate that they are staying up to date and advancing in their roles.This series gives an overview of each type of examination to support students, newly qualified paramedics and paramedics wishing to use these articles as a CPD development activity and an aide-memoire for clinical practice. This article, which explores the the gastrointestinal system, gives an overview of initial examination considerations.
Population genetic structure of blue swimming crab (Portunus pelagicus) in the Gulf of Thailand
Authors: SUPMEE VERAKIAT , SAWUSDEE AMONSAK , SANGTHONG PRADIT , SUPPAPAN JUTHAMAS 
Published: September 2020

Abstract. Supmee V, Sawusdee A, Sangthong P, Suppapan J. 2020. Population genetic structure of Blue Swimming Crab (Portunus pelagicus) in the Gulf of Thailand. Biodiversitas 21: 4260-4268. The Blue Swimming Crab (Portunus pelagicus) is an important commercial fishery product in the Gulf of Thailand. To provide a strategy for management, information on genetic features is needed. In our study, the population genetic structure and demographic history of the P. pelagicus living in the Gulf of Thailand were analyzed based on the variation of the nucleotide sequence of the mitochondrial DNA in the control region (mtDNA CR). Ninety-seven samples were collected from 5 sampling sites: Rayong, Chonburi, Chumphon, Surat Thani, and Nakhon Si Thammarat provinces in the Gulf of Thailand. Forty-nine haplotypes were identified and 39 private haplotypes were found. An AMOVA showed no genetic structure among populations. The pairwise FST also indicated no statistically significant difference between all possible regional combinations. The topology of a minimum spanning network revealed a star-like topology that was not separated by geographic structure. The historical demographic analysis revealed a stable population size for a long period and followed by a very recent expansion. An absence of a population structure of the P. pelagicus was possibly caused by a high level of gene flow. The results of this study differ from previous studies that used genetic markers in nuclear DNA. Thus, to clear the genetic structure information of P. pelagicus in the Gulf of Thailand, we suggested that more sensitive markers to detect genetic structure should be used in further analysis.
Fumigant and feeding deterrent activity of essential oils against Cryptolestes ferrugineus (Stephens) (Coleoptera: Laemophloeidae)
Authors: Ikawati Silvi , Himawan Toto , Abadi Abdul Latief , Tarno Hagus 
Published: September 2020

Abstract. Ikawati S, Himawan T, Abadi AL, Tarno H. 2020. Fumigant and feeding deterrent activity of essential oils against Cryptolestes ferrugineus (Stephens) (Coleoptera: Laemophloeidae). Biodiversitas 21: 4301-4308. This study aimed to determine the fumigant and antifeedant activity of some plant essential oils against Cryptolestes ferrugineus. Essential oils were extracted from cinnamon (Cinnamomum verum), kaffir lime (Citrus hystrix), citronella grass (Cymbopogon nardus), zodea (Euodia suaveolens), and clove (Syzygium aromaticum). The extraction used the maceration method with n-Hexane as a solvent. The results of the experiments showed that all essential oils have fumigant toxicity. Fumigant toxicity of kaffir lime, citronella grass, zodea, and clove oil; eggs and pupae were more susceptible than adults and larvae, while for cinnamon, pupae and adults were more susceptible than eggs and larvae. Median Lethal Concentration (LC50) of all essential oils for eggs larvae, pupae, and adults respectively, for cinnamon were 17, 24, 9, and 12 ppm, for kaffir lime were 12, 17, 8 and 15 ppm, however, on citronella grass were 11, 22, 8, and 14 ppm, for zodea were 16, 22, 10 and 20 ppm, for clove were 11, 24, 7 and 14 ppm. The fifth essential oils showed antifeedant activity in a no-choice test against C. ferrugineus adults. Also, the fifth essential oils significantly reduced the relative growth rate (RGR), relative consumption rate (RCR), and food utilization (ECI) of C. ferrugineus adults. It shows that the essential oils have great potential as one of the storage pest control components.
The Laws of Knowledge, Knowledge of Laws
Authors: Herzog Lisa 
Published: September 2020

Abstract
This commentary, part of the book symposium on Katharina Pistor’s The Code of Capital, focuses in particular on the epistemic dimensions of the phenomena she describes. Knowledge can be coded as capital, through intellectual property rights, and these can be done in ways that unjustly favor privileged actors at the cost of the common good, as Pistor demonstrates with regard to the patenting of genetic markers. Interestingly, however, knowledge can also be appropriated without the use of legal tools, simply by appropriating data from consumers, as Zuboff, for example, has argued. A second epistemic dimension of Pistor’s work lies in the fact that the legal coding of capital is itself little know and receives little public discussion. This, of course, plays into the hands of those who benefit by problematic forms of such coding. By putting these issues up for debate, The Code of Capital fulfill itself an important epistemic role, which can be categorized as a form of "democratic professionalism", i.e., professionals enabling a critical public discourse about the activities in their own field.
The Trade-off Between Household Expenditures and Smoking Expenditure: Pre and Post Smoking Awareness Ordinance in Pakistan
Authors: Ali Basit , Irfan Muhammad 
Published: September 2020

Abstract
The Government of Pakistan introduced smoking ordinance about health warning in 2009. This ordinance exhibits, prohibit smoking in public places, put restrictions on advertisements, and prohibits sale of cigarettes to minors. This study is to find out the impact of smoking expenditures on food, health, educational, recreational, and electronic expenditures using HIES dataset for 2010–11 and 2015–16. The findings show that share of food and health expenditure increase by 91 and 92% respectively. On the other hand, education and recreation expenditure decrease by 6 and 98% respectively. This is further verified using SUEST test to compare two datasets regressions. The result reveals that food, health, and recreational coefficient are statistically different while education and electronics expenditure remain similar.
Hurricane Bond Price Dependency on Underlying Hurricane Parameters
Authors: Chang Carolyn W. , Feng Yalan 
Published: September 2020

Abstract
Hurricane bonds are parametric in nature as they have a dual-exercise structure: the first exercise is conditional on the hurricane’s physical landfall location and the second is conditional upon the embedded option ending in-the-money. We propose a coupled and physically-based hurricane bond pricing model via Monte Carlo simulation that resolves the dual exercise, which was not addressed in extant loss-based catastrophe bond pricing models. This coupled model is developed at the nexus of atmospheric science and finance by integrating hurricane risk modeling and option pricing. By applying this model to price a parametric hurricane bond, we demonstrate how a hurricane bond’s price is sensitive to its underlying hurricane’s physical parameters – genesis, heading, translation speed, velocity, and radius.
Verbesserung der Netzverlustprognose für Energieübertragungsnetze
Authors: Klaiber Stefan , Bauer Fabian , Bretschneider Peter 
Published: September 2020

Zusammenfassung
Bei der Energieübertragung entstehen Netzverluste in den Leitungen und Betriebsmitteln des elektrischen Energiesystems. Die Höhe der Netzverluste ist sowohl von der Netzlast als auch von zahlreichen weiteren Einflussgrößen abhängig. Einen besonderen Einfluss hat dabei die fluktuierende und größtenteils verbrauchsferne Erzeugung durch erneuerbare Energien. Die Übertragungsnetzbetreiber müssen die elektrische Energie zum Ausgleich der Netzverluste im Voraus beschaffen. Um die benötigte Ausgleichsenergie möglichst kostenminimal einzukaufen, ist eine genaue Prognose der Netzverluste notwendig. Im Rahmen des vorliegenden Beitrags wird ein Verfahren vorgestellt, das für die Prognose der Netzverluste im Übertragungsnetz der 50Hertz Transmission GmbH zum Einsatz kommt. Als Modellansatz der Prognosemethode werden Künstliche Neuronale Netze verwendet. Das als Ergebnis der Arbeiten entwickelte Modell für die Netzverlustprognose steigert die Prognosegüte im Vergleich zum bisherigen Modell um sieben Prozent und befindet sich bei 50Hertz seit Juni 2019 im operativen Einsatz.
Sectoral Productivity Gaps and Aggregate Productivity
Authors: Sinha Rishabh 
Published: September 2020

Abstract
The paper examines the aggregate impact of misallocation measured using gaps in labor productivity across sectors. A simple model of resource allocation is used to quantify the effect in which the gaps arise due to distortions in the form of asymmetrical taxes on hiring labor across sectors. From a development accounting approach, the gains from eliminating distortions are meager and are not consequential in accounting for cross-country variation in incomes. Nevertheless, the gains for some countries rival the growth that they have accumulated over several years. Of the 87 countries in the sample, the changes in distortions over time exert a net negative impact in 45 countries instead of providing tailwinds to growth. Changes in distortions account for just under 5.6% of the total growth when aiding growth. In turn, the output drag represents 3.4% of the actual growth on average for the sub-sample in which distortions yield a net negative effect. The move towards allocative efficiency bears a positive association with the quality of institutions.
Emicizumab, the factor VIII mimetic bi-specific monoclonal antibody and its measurement in plasma
Authors: Tripodi Armando , Chantarangkul Veena , Novembrino Cristina , Scalambrino Erica , Boscolo-Anzoletti Massimo , Clerici Marigrazia , Rossi Federica , Peyvandi Flora 
Published: September 2020

Abstract

Objectives
Emicizumab, a monoclonal antibody mimicking the function of factor (F) VIII in the activation of FX by FIXa, is widely used for prophylaxis in hemophilia patients with or without inhibitors to FVIII. Although it is administered at fixed dose, its measurement could be occasionally required. In principle, the emicizumab procoagulant effect could be assessed by the one-stage assay (OSA) currently used to measure FVIII. However, the OSA for FVIII presents with limitations. Furthermore, owing to its potent FVIII-like activity, emicizumab interferes with the measurement of the inhibitor to FVIII, which is often needed in patients on emicizumab.

Methods
We prepared test samples by spiking a FVIII-deficient plasma with graded amounts of emicizumab. We modified the OSA for FVIII and tested plasma samples for emicizumab concentrations. Furthermore the chromogenic assay (CA) for FVIII with bovine reagents was used to assess for the FVIII inhibitor in patients on emicizumab.

Results
Slight modification of the OSA for FVIII (i.e., higher test plasma dilution and longer coagulometer acquisition time) made the regular OSA as a reliable laboratory tool to measure emicizumab concentration as shown by the identity of the regression (observed vs. expected) lines. Furthermore, the inhibitors to FVIII in patients on emicizumab, which were negative when measured by the regular Bethesda assay, were reliably measured by the CA assay employing bovine reagents.

Conclusions
The methods currently used to measure FVIII can be easily modified to make the general clinical laboratory able to assist clinicians when dealing with patients on emicizumab.
The impact of an instruction to improve L2 learners’ academic conference abstract writing in multidisciplinary programmes
Authors: Ioratim-Uba Godwin 
Published: September 2020

Abstract
Writing successful academic conference abstracts is essential for PhD students to enable them to access world-class conferences for the presentation of their research. However, these students often face both discourse-structure and linguistic difficulties in writing their conference abstracts. This study evaluates the impact of genre, process, elicitation and guided learning instruction on students’ performance in academic conference abstract writing. Participants are multidisciplinary L2 PhD students at a Sino-British university. The first dataset used for the impact evaluation comprises post-intervention written abstracts collected from 10 focal students. To evaluate the instruction, a scoring descriptor instrument adapted from the university’s academic writing assessment rubric is used to grade the abstracts’ move-structure, and linguistic features of cohesion, hedging, passive, and present simple. Trends in the scores are analysed statistically. The second dataset consists of students’ questionnaire-elicited experiences of the instruction. Findings show improvements in post-intervention abstracts’ move-structures and linguistic features, which suggests pedagogical effectiveness. Questionnaire responses also display positive perceptions of the pedagogy. Due to the impact of disciplinary genre materials, disciplinary discrepancy is more evident in linguistic structures than in move structures. Writer characteristics also appear to gravitate towards a discipline-centric writing ethos due to the impact of disciplinary-genre materials and the desire to enhance the abstract’s selection chances. Thus, there is potential for language-feature functions, process writing, exact-genre materials and interactive learning process pedagogies to mediate learning and improvement in disciplinary L2 writing.