bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribusi neuron serotonergik pada hipokampus Lasiwen (Myotis sp) sebagai satwa liar yang berpotensi menjadi reservoir virus rabies
Authors: Pangestiningsih Tri Wahyu , Ariana Ariana , Padeta Irma , Jadi Arvendi Rahma , Wendo Woro Danur 
Published: November 2019

Myotis sp is an Indonesian microchiropteran, insectivore bat that potential to be a reservoir for rabies virus. Rabies is fatal viral encephalitis and bat could act as wildlife potential reservoirs for the rabies virus and can transmit the disease to humans as the zoonotic disease. Hippocampus is one of diagnostic tissue for rabies disease and serotonergic neuron could involved in pathogenesis of rabies disease. The aim of the study is to investigate the distribution of serotonergic neurons in Myotis sp hippocampus. Five Myotis sp. were captured from wild population in Central Java, and were humanly anesthetized using ketamine and xylazin. The animals were perfused intracardially using NaCl 0.9% as the pre-rinse followed by 10% formaldehyde to fix it. The cerebrums were collected and processing the for paraffin embedding. Cerebrums were sectioning in saggital sections, 12 µm thickness serially with 120 µm intervals. The tissues were staining immunohistochemistry using antibody to serotonin (1/300; Bioss, Cat. No: bs-1126R) 2 night incubation in 4 oC temperature. The solution for blocking background, secondary antibody, avidin-biotin-peroxidae complex and chromogen using kit Starr Trek Universal HRP Detection System (Biocare Medical, Cat No: STUHRP700) and were analyzed descriptivelly. The results show that serotonergic neuros were distributed in the all area of the of Myotis sp hippocampus. In dentate gyrus neuron serotonergic (Sert-IR)s are round in shape and mostly distributed in the middle layer, few in the superficially also deeper layers. In the hippocampus , the Sert-IR neurons are pyramidal in shape and distributed in the CA1, Ca2 and CA3 areas. In subiculum, the Sert-IR neurons are pyramidal in shape, more wider distributed than in the CA1 with no differences between outer layer and deeper layer. The conclutions of this research are the serotonergic neurons are distributed in the all area of hippocampus
Pengaruh Pemberian Serum Albumin Manusia terhadap Kadar Albumin dalam Darah pada Anjing dengan status Hipoalbuminemia
Authors: Merthayasa Julita Dewitri , Devi Jayanti Putu Devi , Indarjulianto Soedarmanto , Permana Ryan Hadi , Destinanda Nadia Liswardani , Wijayanti Agustina Dwi 
Published: November 2019

Albumin consists of 50% of the total plasma protein and it is very important protein in the animal's body. Hypoalbuminemia can occurs due to various conditions, such as loss of protein nephropathy, loss of enteropathic proteins, chronic and acute diarrhea or heavy bleeding as well as malnutrition and malabsorption conditions. This study aims to determine the effect of human serum albumin 20% infusion to increase albumin blood level in hypoalbuminemia dogs. Animals used in this study were 5 dogs whose results showed the levels of albumin below normal limits or hypoalbuminemia. Dogs with hypoalbuminemia will be infused with human serum albumin (HSA) 20% through intravenous for ± 4 hours. Then, these dogs blood will be drawn days after infusion to screen for albumin levels. The results obtained in the form of examination data of albumin blood levels in the blood before and after infusion will be analyzed with paired T-test. The results showed an increase of albumin level significantly from an average of 1.98 ± 0.356 to 2.28 ± 0.257(P <0.05). This study shows the presence of human albumin serum through intravenous infusion was able to increase albumin levels in dogs with hypoalbuminemia.
Economic Evaluation of Quality Improvement Interventions Designed to Improve Glycemic Control in Diabetes: A Systematic Review and Weighted Regression Analysis
Authors: Nuckols Teryl K. , Keeler Emmett , Anderson Laura J. , Green Jonas , Morton Sally C. , Doyle Brian J. , Shetty Kanaka , Arifkhanova Aziza , Booth Marika , Shanman Roberta , Shekelle Paul 
Published: November 2019

OBJECTIVEQuality improvement (QI) interventions can improve glycemic control, but little is known about their value. We systematically reviewed economic evaluations of QI interventions for glycemic control among adults with type 1 or type 2 diabetes.RESEARCH DESIGN AND METHODSWe used English-language studies from high-income countries that evaluated organizational changes and reported program and utilization-related costs, chosen from PubMed, EconLit, Centre for Reviews and Dissemination, New York Academy of Medicine's Grey Literature Report, and WorldCat (January 2004 to August 2016). We extracted data regarding intervention, study design, change in HbA1c, time horizon, perspective, incremental net cost (studies lasting ≤3 years), incremental cost-effectiveness ratio (ICER) (studies lasting ≥20 years), and study quality. Weighted least-squares regression analysis was used to estimate mean changes in HbA1c and incremental net cost.RESULTSOf 3,646 records, 46 unique studies were eligible. Across 19 randomized controlled trials (RCTs), HbA1c declined by 0.26% (95% CI 0.17–0.35) or 3 mmol/mol (2 to 4) relative to usual care. In 8 RCTs lasting ≤3 years, incremental net costs were $116 (95% CI −$612 to $843) per patient annually. Long-term ICERs were $100,000–$115,000/quality-adjusted life year (QALY) in 3 RCTs, $50,000–$99,999/QALY in 1 RCT, $0–$49,999/QALY in 4 RCTs, and dominant in 1 RCT. Results were more favorable in non-RCTs. Our limitations include the fact that the studies had diverse designs and involved moderate risk of bias.CONCLUSIONSDiverse multifaceted QI interventions that lower HbA1c appear to be a fair-to-good value relative to usual care, depending on society’s willingness to pay for improvements in health.
PEMBELAJARAN BERBASIS EDMODO PADA MAHASISWA PENDIDIKAN MATEMATIKA UNIVERSITAS BALIKPAPAN
Authors: Pratama Ryan Angga , Ismiyati Nur 
Published: November 2019

Penelitian ini bertujuan untuk mendeskripsikan pelaksanaan pembelajaran berbasis Edmodo pada mahasiswa Pendidikan Matematika Universitas Balikpapan. Subjek dalam penelitian ini adalah 12 mahasiswa Pendidikan Matematika Universitas Balikpapan yang sedang menempuh perkuliahan Teori Bilangan. Teknik pengumpulan data dilakukan dengan observasi (pengamatan terhadap aktivitas chat di dalam Edmodo), dokumentasi, serta tes hasil belajar. Adapun hasilnya didapatkan bahwa pelaksanaan pembelajaran berbasis Edmodo berjalan dengan baik. Hal ini dapat dilihat dari capaian hasil belajar mahasiswa yang menunjukkan secara rata-rata dari 12 mahasiswa memperoleh skor atau ketercapaian 82,53. Selain itu, mahasiswa juga merasa memperoleh pengalaman belajar yang baru melalui Edmodo, dapat lebih berekspresi, suasana belajar (chat) sangat santai, serta dapat diakses dimana saja jika mahasiswa lupa materi yang telah dipelajarinya. Hal ini dikarenakan materi yang disajikan telah diunggah di Edmodo maupun kanal Youtube. AbstractThis study aims to describe the implementation of Edmodo-based learning in Mathematics Education students at the University of Balikpapan. The subjects in this study were 12 University of Balikpapan Mathematics Education students who were taking lectures on Number Theory. Data collection techniques are done by observation (observation of chat activities in Edmodo), documentation, and learning achievement tests. The results were obtained that the implementation of Edmodo-based learning went well. This can be seen from the achievements of student learning outcomes which show an average of 12 students get a score or achievement of 82,53. In addition, students also feel they have gained a new learning experience through Edmodo, can be more expressive, the atmosphere of learning (chat) is very relaxed, and can be accessed anywhere if students forget the material they have learned. This is because the material presented has been uploaded on Edmodo and the Youtube channel.
PENGARUH MODEL PEMBELAJARAN TREFFINGER TERHADAP PEMAHAMAN KONSEP DAN KECAKAPAN BERPIKIR RASIONAL PESERTA DIDIK
Authors: Latifah Sri , Basyar Syarifuddin , Sasmiyati Bangun 
Published: November 2019

Pendidik masih menggunakan model konvensional yang didominasi dengan metode ceramah sehingga peserta didik mengalami kebosanan dalam proses pembelajaran. Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Treffinger terhadap pemahaman konsep dan kecakapan berpikir rasional peserta didik SMA pada materi alat-alat optik. Populasi pada penelitian ini adaalah seluruh kelas XI SMA N 1 Sendang Agung, Lampung, Tengah, dan sampel yang dipilih dengan teknik purposive sampling kelas XI MIPA 1 sebagai kelas eksperimen dan kelas XI MIPA 3 sebagai kelas kontrol. Metode penelitian yang digunakan adalah quasy eksperimen dengan desain Nonequivalent Control Group Desaign. Data yang diperoleh dianalisis menggunakan ujji multivariate (MANOVA). Berdasarkan hasil penelitian menunjukkan perbedaan hasil pemahaamaan konsep dan berpikir rasional pada kelas eksperimen dan kontroldengan rata-rata n-gain lebih besar kelas eksperimen dibandingkan kelas kontrol, dan hasil uji multivariate diperoleh tingkat signifikan 0,00 < α dengan α = 0,05. Sehingga H0 ditolak dan H1 diterima, ini menunjukkan bahwa terdapat pengaruh model pembelajaran Treffinger terhadap pemahaman konsep dan kecakapan berpikir rasional siswa kelas XI MIPA SMA Negeri 1 Sendang Agung Lampung Tengah.
CMALT and cMOOC - a community of educators and their learning technologies
Authors: Ransom Lisa 
Published: November 2019

CMALT is a peer-reviewed accreditation based upon the UKPSF (UK Professional Standards Framework) to enable staff (whether academic or administrative) who embed learning technologies in either their teaching or support roles, to showcase their experiences and gain recognition. This programme has been developed by ALT and is co-delivered online, by ASCILITE.

Building upon the experiences of supporting a geographically distributed project involving six institutions nationally across New Zealand during 2014-2015, we (AUT) have developed a support structure for building communities around CMALT accreditation using a cMOOC model. The cMOOC framework enables us to bridge and broker authentic participation within an international community of academics and learning technologists interested in exploring CMALT accreditation, and we have had participation from the UK, Japan, Canada, Australia, and NZ. The CMALT cMOOC was developed in 2017 by the Centre for Learning and Teaching, at Auckland University of Technology, and endorsed by ALT and ASCILITE in 2019.

This presentation will highlight the ecology of resources that are used to support the community and hear from current participants of the programme
PRNG Implementation Based on Chaotic Neural Network (CNN)
Authors: Mohammed Mohammed J. 
Published: November 2019

In this work, a neural network with chaos activation function has been applied as a pseudo-random number generator (PRNG). Chaotic neural network (CNN) is used because of its noise like behaviour which is important for cryptanalyst to know about the hidden information as it is hard to predict. A suitable adaptive architecture was adopted to generate a binary number and the result was tested for randomness using National Institute of Standard Technology (NIST) randomness tests.
Although the applications of CNN in cryptography have less effective than traditional implementations, this is because these systems need large numbers of digital logic or even a computer system. This work will focus on applications that can use the proposed system in an efficient way that minimize the system complexity.
Features of arterial hypertension in postmenopausal women with abdominal obesity: The role of inflammatory response markers, leptin, and female sex hormones in the pathogenesis of vascular wall stiffness
Authors: Avdeeva K. S. , Petelina T. I. , Gapon L. I. , Musikhina N. A. , Zueva E. V. 
Published: November 2019

Background. Despite overall efforts, arterial hypertension remains one of the most significant medical and social problems. The risk of developing arterial hypertension is tripled in obese individuals compared with people who have normal body weight. According to clinical studies, individual biochemical markers can be predictors of initiation of remodeling processes in systems at a preclinical level. Endothelial dysfunction is the initial stage in the development of atherosclerosis. Mechanisms of the vascular inflammatory response in arterial hypertension with obesity can be considered a factor that largely determines the onset and course of the disease, a cause of its aggravation, development, and progression. Cardiovascular risk factors, genetic predisposition, deficit of sex hormones, and aging affect the endothelium function.Aim. To study specifics of hypertension in postmenopausal women with abdominal obesity and to evaluate the role of inflammatory response markers, leptin, and female sex hormones in the pathogenesis of vascular wall stiffness.Material and Methods. The study included 164 patients divided into three groups. Group 1 consisted of 42 healthy women aged 44.43 ± 14.26 years; group 2 comprised 62 hypertensive women aged 60.69 ± 7.09 years; group 3 comprised 60 hypertensive women with abdominal obesity aged 57.24 ± 7.40 years. Patients of all groups received 24-hour blood pressure monitoring, sphygmography, and assessment of sex hormones, lipids, inflammatory, and biochemical parameters in blood serum.Results. Results of analysis showed that patients of group 3 had significantly higher blood pressure compared with that in group 2. Higher pulse wave velocity was observed in women of group 2. Groups 2 and 3 had lower levels of sex hormones and significant increases in the levels of inflammatory markers compared with those in control group. Multiple multidirectional correlations between the studied parameters were revealed.Conclusions. Features of hypertension in postmenopausal women with obesity consist in a systolic-diastolic variant of hypertension, an increase in systolic blood pressure variability at night, an increase in diastolic blood pressure during the daytime, and increases in systolic and diastolic blood pressure at night. The method of logistic regression allowed to identify biochemical markers that determine the elastic properties of the vascular wall in this category of patients, namely: leptin, highsensitivity C-reactive protein, and endothelin-1.
Cardiac pathology in patients with resistant hypertension
Authors: Mordovin V. F. , Ripp T. M. , Sitkova E. S. 
Published: November 2019

Patients with resistant arterial hypertension have a high prevalence of cardiac pathology. In particular, left ventricular hypertrophy and reduced coronary reserve play independent role in determining the risk of cardiovascular complications. Diagnostic approaches to their detection are currently represented by a wide range of highly informative studies using modern ultrasound equipment, magnetic resonance imaging, computed tomography scanner, and gamma camera. The active study of the involvement of the cascade of pathophysiological mechanisms in the development of cardiac changes in hypertension allows not only to identify the factors associated with the severity of the lesion, but also to find new application points for the cardioprotection and to reduce cardiovascular risk. Along with the pharmacological capabilities, the renal denervation method is currently under active study. Despite high variability of the results and their poor predictability, a number of studies show the efficiency of this method in correcting the structural and functional changes in the heart, which is of important prognostic value for resistant hypertension.
Kuoleman esittäminen Lauri Viidan lyriikassa
Authors: Turunen Mikko 
Published: November 2019

Artikkelissani törmäytän toisiinsa kirjallisuudentutkimuksen tekstianalyysia ja kuolemantutkimuksen mallintamia tapoja esittää ja merkityksellistää kuolema. Törmäyttämisellä on pyritty pois joskus kapeana nähdystä rajauksesta, jossa kaunokirjallisuudessa esiintyviä kuoleman representaatioita lähestytään vain teemoina, trooppeina tai sanataiteen estetisoituina kohteina, siis eräänlaisena kuoleman kirjallistumisena (”literaturization of death”, Teodorescu 2015a, 2).
Uutta tietoatuotanyhdistämällä kuolematutkimuksen monitieteisiä näkökulmia kirjallisuustieteelliseen tekstianalyysiin sekä analysoimalla Lauri Viidan (1916–1965) vähän tai ei lainkaan tutkittuja runoja, joissa ilmenee keskenään erilaisia tapoja käsitellä sekä konkreettista kuolemista että kuoleman abstraktiota.Kuoleman filosofia ja kuoleman kulttuurihistoria tarjoavat hyödyllisiä työkaluja tunnistaa ajattelukehikoita, jotka heijastuvat runon puhujan kuolemasuhteen käsittelyssä ja ilmaisuvalinnoissa.
Tässä artikkelissa analysoin ensin kahta ulkoisesti pienimuotoista mutta kuolemasuhteen kannalla moniulotteista runoa (”Mutta, muisti muurahainen” ja ”Tiedonpuu”). Sen jälkeen tarkastelen väkivaltaisen kuoleman aihetta (mm. ”Pedot”, ”Vallankumous” ja ”Legenda”) sekä variaatioita olemassaolon rajat ylittävästä jatkuvuudesta (mm. ”Mitä mietin mullan alla” ja ”Julku”). Lopuksi nostan lyhyesti esiin joitakin muita Viidan runojen tapoja esittää kuolema.Yksittäiset runot tarjoavat keskenään erilaisia kuvauksia, käsitteistyksiä ja tulokulmia olemassaolon rajallisuuden kysymyksiin.
The Role and Rise of Interprofessional Continuing Education
Authors: Regnier Kate , Chappell Kathy , Travlos Dimitra V. 
Published: November 2019

ABSTRACT
For decades, health leadership organizations have identified interprofessional education and team-based care as a critical component of health care quality and safety. The Institute of Medicine (IOM) has issued a series of reports demonstrating the relationship between poor team performance and negative patient outcome and has called on accreditors, licensing and certifying bodies to use their oversight processes as levers for change. Toward that end, three of the national accreditors in medicine, nursing and pharmacy collaborated to create a unified accreditation system, setting standards for interprofessional continuing education (IPCE) and establishing an IPCE credit that designates activities planned by and for health care teams. There is evidence supporting the relationship between engagement in IPCE and improvements in health care professionals' knowledge, attitudes, competence and performance, as well as patient and system outcomes. The accreditors believe that this evidence base is strong enough to justify including IPCE in regulatory requirements. In 2018, the Federation of State Medical Boards (FSMB) recognized IPCE credit as an additional means of satisfying CME requirements for medical license renewal. The increasing recognition of IPCE demonstrates the pivotal role of accreditors and regulators in driving the advancement of IPCE and team care now and in the future.
İTALYA’NIN EMILIA-ROMAGNA BÖLGESİ YENİLİK STRATEJİSİ’NİN (PRRIITT ) ANALİZİ
Authors: ÇELİK Fatih 
Published: November 2019

ÖZ İtalya’nın Emilia-Romagna (E-R) bölgesi, kendine özgü kalkınma yaklaşımı ile literatürde “Emilian Modeli” olarak yer almıştır. Model, aktörler arası işbirliği (yönetişim), destekleyici yerel yönetim, mesleki ve teknik eğitim, sosyal sermaye gibi bölgenin sosyo-ekonomik unsurlarına dayanmaktadır. İtalya’da 1970’lerde bölgelere, kalkınma ajansı kurma yetkisi verilmiştir. Bu doğrultuda E-R, Bölgesel Kalkınma Ajansı olarak ERVET’i (1974) kurmuştur. ERVET, KOBİ’lerin kümelenmesini ve yenilik faaliyetlerini desteklemek için Reel Hizmet Merkezleri (RSCs); bunları birleştirerek de ERVET Sistemi’ni kurmuştur. Bölge yönetimi, E-R’nin sanayi toplumu olması için I. Sanayi Politikası’nı (1993); bilgi toplumuna dönüşmesi için de Bölgesel Yenilik Stratejisi olarak II. Sanayi Politikası’nı (PRRIITT, 2002) hazırlamıştır. PRRIITT’in temel amacı, bölgenin Ar-Ge ve yenilik yapma kapasitesinin geliştirilmesidir. Uygulama sorumluluğu, bir RSC olan ASTER’e (Teknoloji Geliştirme Merkezi) verilmiştir. PRRIITT kapsamında Ar-Ge ve yenilik alanlarında yaklaşık 370 milyon € yatırım yapılmıştır. Çalışmanın amacı, PRRIITT’in amacı, yönetimi, finansmanı ve sonuçları bakımından analiz edilmesidir. Konu, nitel araştırma yöntemlerinden doküman analizi tekniği ile incelenmiştir. PRRIITT kapsamında Ar-Ge laboratuvarları, yenilik merkezleri gibi kurumların ve bunları birbirine bağlamak için de İleri Teknoloji Ağı’nın (HTN); sonuçta da Bölgesel Yenilik Sistemi’nin kurulduğu belirlenmiştir.
MİLLİ EĞİTİM BAKANLIĞI SÖZLEŞMELİ ÖĞRETMENLİK UYGULAMASININ KAMU POLİTİKASI AÇISINDAN DEĞERLENDİRİLMESİ
Authors: GÜRCÜOĞLU Sinan 
Published: November 2019

Türk
kamu yönetiminde eğitim alanında kamu politikaları, etkisi ve kapsamı açısından
büyük önem taşımaktadır. Eğitimin, paydaşları göz önüne alındığında, ülkenin
bütününü ilgilendiren, bugünü olduğu kadar geleceği de içine alan bir niteliği
bulunmaktadır. Bu nedenledir ki eğitim, ülkenin geleceğine ilişkin kararlar
verecek olan nesillerin yetiştirilmesi bakımından önemlidir. Önemi
doğrultusunda da eğitimin kalitesini artırmak amacına yönelik olarak zaman
zaman uygulanan politikalar üzerinde köklü değişikliklere gidilmekte ya da
mevcut politikalar tümden kaldırılarak yerine yenileri getirilmektedir. Bu yola
başvurulmasının nedenleri arasında ise ortaya konulan politikalarla eğitimin
niteliği ve kalitesinde arzulanan sonuçlara ulaşılamaması başta gelmektedir. Milli
Eğitim Bakanlığında eğitim politikalarının özellikle insan kaynakları boyutunda
sıkça değiştiği gözlenmektedir. Bu değişikliklerin ülke çapında geniş boyutlu
etkileri bulunmakta gerek sivil toplum kuruluşları gerekse medya tarafından sık
sık gündeme getirilmektedir. Son yıllarda uygulamaya konulan bu politikalardan sözleşmeli
öğretmenlik uygulaması ülke gündeminde önemli yer tutan ve çeşitli taraflarca meşruiyeti
üzerinde uzun süreli tartışmalara neden olan politikalardan biridir. Bu
çalışmada; kamu politikası, kamu politikası analizi, kamu politikası sürecinin
kavramsal boyutları açıklanmakta ve Milli Eğitim Bakanlığında sözleşmeli öğretmenlik
uygulanmasına ilişkin süreçler ele alınmaktadır. Ardından sözleşmeli öğretmen
istihdamı politikası süreç modeline göre analiz edilmek suretiyle kamu
politikası analizi bağlamında sözleşmeli öğretmenlik uygulamasının Türkiye’nin eğitim
alanında getirdiği yenilikleri, etkilerini ve önemini ortaya çıkarmak
amaçlanmış, bu doğrultuda eleştiri ve öneriler sunulmuştur.Anahtar
Kelimeler: Kamu Politikası, Kamu Politikası
Analizi, Kamu Politikası Süreci, Sözleşmeli Öğretmenlik, Milli Eğitim
Bakanlığı.Jel Kodları: I 28
INFORMASI KEBIJAKAN LARANGAN KANTONG PLASTIK TERHADAP MINAT BELI TAS RAMAH LINGKUNGAN
Authors: Pramelani PRAMELANI 
Published: November 2019

Limbah sampah plastik di Indonesia sangat meningkat dan dapat membahayakan bagi lingkungan. Maka, pemerintah memberlakukan kebijakan larangan kantong plastik sekali pakai. Ada beberapa daerah yang telah menetapkan kebijakan tersebut. Sedangkan, pemerintah di DKI Jakarta sedang mempersiapkan kebijakan larangan kantong plastik sekali pakai. Selama enam bulan, pemerintah mengadakan sosialisasi terhadap kebijakan tersebut. Dan informasi kebijakan larangan kantong plastik sekali pakai sudah diinformasikan dari tahun kemaren. Dan tas ramah lingkungan juga diinformasikan sebagai penggantinya. Penulis tertarik untuk meneliti mengenai informasi kebijakan yang didapatkan oleh masyarakat tersebut. Sehingga, penelitian ini bertujuan untuk mengetahui hubungan Informasi Kebijakan Larangan Kantong Plastik terhadap Minat Beli Tas Ramah Lingkungan. Responden dipilih yang tinggal di daerah DKI Jakarta dan dengan teknik convenience sampling. Metode penelitian yang digunakan adalah kuantitatif. Sedangkan, analisa data diuji dengan korelasi spearman. Hasil dari korelasi tersebut adalah terdapat hubungan yang kuat.antara informasi kebijakan larangan kantong plastik dengan minat beli tas ramah lingkungan
Kata Kunci : Informasi, Kebijakan, Minat Beli