bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using an Electronic App to Promote Home-Based Self-Care in Older Patients With Heart Failure: Qualitative Study on Patient and Informal Caregiver Challenges
Authors: Wali Sahr , Keshavjee Karim , Nguyen Linda , Mbuagbaw Lawrence , Demers Catherine 
Published: October 2020

Background
Heart failure (HF) affects many older individuals in North America, with recurrent hospitalizations despite postdischarge strategies to prevent readmission. Proper HF self-care can potentially lead to better clinical outcomes, yet many older patients find self-care challenging. Mobile health (mHealth) apps can provide support to patients with respect to HF self-care. However, many mHealth apps are not designed to consider potential patient barriers, such as literacy, numeracy, and cognitive impairment, leading to challenges for older patients. We previously demonstrated that a paper-based standardized diuretic decision support tool (SDDST) with daily weights and adjustment of diuretic dose led to improved self-care.

Objective
The aim of this study is to better understand the self-care challenges that older patients with HF and their informal care providers (CPs) face on a daily basis, leading to the conversion of the SDDST into a user-centered mHealth app.

Methods
We recruited 14 patients (male: 8/14, 57%) with a confirmed diagnosis of HF, aged ≥60 years, and 7 CPs from the HF clinic and the cardiology ward at the Hamilton General Hospital. Patients were categorized into 3 groups based on the self-care heart failure index: patients with adequate self-care, patients with inadequate self-care without a CP, or patients with inadequate self-care with a CP. We conducted semistructured interviews with patients and their CPs using persona-scenarios. Interviews were transcribed verbatim and analyzed for emerging themes using an inductive approach.

Results
Six themes were identified: usability of technology, communication, app customization, complexity of self-care, usefulness of HF-related information, and long-term use and cost. Many of the challenges patients and CPs reported involved their unfamiliarity with technology and the lack of incentive for its use. However, participants were supportive and more likely to actively use the HF app when informed of the intervention’s inclusion of volunteer and nurse assistance.

Conclusions
Patients with varying self-care adequacy levels were willing to use an mHealth app if it was simple in its functionality and user interface. To promote the adoption and usability of these tools, patients confirmed the need for researchers to engage with end users before developing an app. Findings from this study can be used to help inform the design of an mHealth app to ensure that it is adapted for the needs of older individuals with HF.
Assessing the Effect of Training on the Cognition and Brain of Older Adults: Protocol for a Three-Arm Randomized Double-Blind Controlled Trial (ACTOP)
Authors: Boujut Arnaud , Mellah Samira , Lussier Maxime , Maltezos Samantha , Verty Lynn Valeyry , Bherer Louis , Belleville Sylvie 
Published: October 2020

Background
To prevent age-related cognitive impairment, many intervention programs offer exercises targeting different central cognitive processes. However, the effects of different process-based training programs are rarely compared within equivalent experimental designs.

Objective
Using a randomized double-blind controlled trial, this project aims to examine and compare the impact of 2 process-based interventions, inhibition and updating, on the cognition and brain of older adults.

Methods
A total of 90 healthy older adults were randomly assigned to 1 of 3 training conditions: (1) inhibition (Stroop-like exercises), (2) updating (N-back-type exercises), and (3) control active (quiz game exercise). Training was provided in 12 half-hour sessions over 4 weeks. First, the performance gain observed will be measured on the trained tasks. We will then determine the extent of transfer of gain on (1) untrained tasks that rely on the same cognitive process, (2) complex working memory (WM) measurements hypothesized to involve 1 of the 2 trained processes, and (3) virtual reality tasks that were designed to mimic real-life situations that require WM. We will assess whether training increases cortical volume given that the volume of the cortex is determined by cortical area and thickness in regions known to be involved in WM or changes task-related brain activation patterns measured with functional magnetic resonance imaging. Dose effects will be examined by measuring outcomes at different time points during training. We will also determine whether individual characteristics moderate the effect of training on cognitive and cerebral outcomes. Finally, we will evaluate whether training reduces the age-related deficit on transfer and brain outcomes, by comparing study participants to a group of 30 younger adults.

Results
The project was funded in January 2017; enrollment began in October 2017 and data collection was completed in April 2019. Data analysis has begun in June 2020 and the first results should be published by the end of 2020 or early 2021.

Conclusions
The results of this study will help understand the relative efficacy of 2 attentional control interventions on the cognition and the brain of older adults, as well as the moderating role of individual characteristics on training efficiency and transfer.

Trial Registration
ClinicalTrials.gov NCT03532113; https://clinicaltrials.gov/ct2/show/NCT03532113

International Registered Report Identifier (IRRID)
DERR1-10.2196/20430
Infection-Related Acute Care Events among Patients with Glomerular Disease
Authors: Glenn Dorey A. , Henderson Candace D. , O’Shaughnessy Michelle , Hu Yichun , Bomback Andrew , Gibson Keisha , Greenbaum Larry A. , Zee Jarcy , Mariani Laura , Falk Ronald , Hogan Susan , Mottl Amy ,   on behalf of the CureGN Consortium
Published: October 2020

Background and objectivesInfections contribute to patient morbidity and mortality in glomerular disease. We sought to describe the incidence of, and identify risk factors for, infection-related acute care events among Cure Glomerulonephropathy Network (CureGN) study participants.Design, setting, participants, & measurementsCureGN is a prospective, multicenter, cohort study of children and adults with biopsy sample–proven minimal change disease, FSGS, membranous nephropathy, or IgA nephropathy/vasculitis. Risk factors for time to first infection-related acute care events (hospitalization or emergency department visit) were identified using multivariable Cox proportional hazards regression.ResultsOf 1741 participants (43% female, 41% <18 years, 68% White), 163 (9%) experienced infection-related acute care events over a median follow-up of 17 months (interquartile range, 9–26 months). Unadjusted incidence rates of infection-related acute care events were 13.2 and 6.2 events per 100 person-years among pediatric and adult participants, respectively. Among participants with versus without corticosteroid exposure at enrollment, unadjusted incidence rates were 50.6 and 28.6 per 100 person-years, respectively, during the first year of follow-up (adjusted hazard ratio for time to first infection, 1.31; 95% CI, 0.89 to 1.93), and 4.1 and 1.1 per 100 person-years, respectively, after 1 year of follow-up (hazard ratio, 2.99; 95% CI, 1.54 to 5.79). Hypoalbuminemia combined with nephrotic-range proteinuria (serum albumin ≤2.5 g/dl and urinary protein-creatinine ratio >3.5 mg/mg), compared with serum albumin >2.5 g/dl and urinary protein-creatinine ratio ≤3.5 mg/mg, was associated with higher risk of time to first infection (adjusted hazard ratio, 2.49; 95% CI, 1.51 to 4.12).ConclusionsAmong CureGN participants, infection-related acute care events were common and associated with younger age, corticosteroid exposure, and hypoalbuminemia with proteinuria.
The prevalence, disease characteristics and treatment of chronic venous disease: an international web-based survey
Authors: Rabe Eberhard , Régnier Catherine , Goron Fabienne , Salmat Ghislaine , Pannier Felizitas 
Published: October 2020

Aim:
This study assessed the characteristics of individuals with chronic venous disease (CVD) and their treatment pathways.
Materials & methods:
A web-based survey enrolled representative populations of adults from Brazil, Czech Republic, France, Hungary, Italy, Romania, Russia and Spain, and identified those self-reporting CVD.
Results:
A total of 22% of respondents had signs/symptoms of CVD. Individuals with CVD were generally older, female and obese, and had more comorbidities than the general population. Common initial symptoms were tiredness, heaviness, pain, swelling in legs and night cramps. Participants waited ∼1 year before seeking treatment but most did not initially consult a physician; those who did tended to have more severe disease.
Conclusion:
One in five adults had CVD, but most did not seek a physician's help.
The prevalence, characteristics and treatment of hemorrhoidal disease: results of an international web-based survey
Authors: Sheikh Parvez , Régnier Catherine , Goron Fabienne , Salmat Ghislaine 
Published: October 2020

Background:
This international study assessed the characteristics and treatment of individuals with hemorrhoids.
Materials & methods:
Online survey among nationally representative populations of adults from Brazil, Czech Republic, France, Hungary, Italy, Romania, Russia and Spain, that identified participants who self-reported having hemorrhoidal disease.
Results:
Hemorrhoid prevalence was 11% (1725/16015); most respondents had low-severity disease (71%). Compared with the general population, participants with hemorrhoidal disease had more comorbidities (mean 3.1 vs 1.3) and included more women who had been pregnant (81 vs 68%). Common initial signs/symptoms were pain (60%), bleeding (47%) and discomfort (43%). Hemorrhoid respondents who consulted a physician were more likely to undergo interventions and take medications.
Conclusion:
The prevalence of hemorrhoidal disease in the adult population is 11%, mostly low-severity disease.
“São os escritos que têm mais força e vida”: cultura escrita, imagens, circulação de saberes e de artistas nos quinhentos
Authors: De Albuquerque Fernanda Deminicis 
Published: October 2020

O presente artigo se debruça sobre o ambiente intelectual do século XVI, objetivando examinar algumas das relações estabelecidas entre as culturas escrita e imagética, bem como a circulação que essas culturas puderam alcançar. Procura-se ainda analisar as possibilidades e finalidades de escritos produzidos por artistas, de modo que seja possível uma reflexão sobre a posição que ocupavam nas cortes e suas estratégias de ascensão social, que visavam a desvinculá-los dos estigmas decorrentes do trabalho manual. Por fim, o texto procura, a partir da perspectiva historiográfica de mundialização, contribuir para a discussão da circulação de agentes na Europa dos quinhentos.
Political and Economic Cooperation between Russia and the Slovak Republic: Possible Development Scenarios
Authors: Denisenko V. A. , Malchushkin N. A. 
Published: October 2020

The article is dedicated to recent domestic political transformations in Slovakia and their possible impact on Russian-Slovak relations. The paper studies the main aspects of the current political and economic partnership between the Russian Federation and the Slovak Republic; it is indicated that economic cooperation with Russia remains a relatively significant foreign policy aspect for Slovakia, primarily due to energy supplies. Nevertheless, the gradual decrease in the intensity of bilateral interaction is highlighted. According to the authors, the “anti-Russian pivot” of Slovakia in 2020 can contribute to a further reduction in the scale of Russian-Slovak cooperation; the Slovak elections radically altered the configuration of political forces within the country, the republic’s parliament is led by the opposition forces with clear anti-Russian rhetoric.Considering possible variations of Russian-Slovak political and economic cooperation in the foreseeable future, authors propose moderately optimistic, neutral and pessimistic scenarios. It is underlined that the damage from the predicted deterioration in relations for Russia due to the current trends in bilateral cooperation between the countries is assessed as rather insignificant.
PEMBERIAN AIR REBUSAN DAUN SALAM (Syzygium polyanthum) TERHADAPPENURUNAN KADAR ASAM URAT PADAPENDERITA ASAM URAT DI DUSUN KADISORODESA GILANGHARJO KECAMATAN PANDAK KABUPATEN BANTUL DIY TAHUN 2017
Authors: Setianingrum Pramukti Dian 
Published: October 2020

Latar Belakang :Asam urat adalah senyawa dalam air yang merupakan hasil akhir metabolism purin. Tanda dan gejalanya yaitu peradangan pada sendi yang tertekan, terasa nyeri, dan kemerahan pada daerah yang telah terjadi asam urat, kekakuan serta pembengkakan pada sendi yang tertekan.Data posyandu lansia di dusun kadisoro terdapat 64 lansia menyatakan mepunyai keluhan asam urat. Daun salam di Dusun Kadisoro belum dimanfaarkan sebagai obat herbal karena tidak mengetahui fungsi dan manfaat dari daun salam tersebut.Tujuan:Mengetahui pengaruh pemberian air rebusan daun salam Syzygium polyanthum) terhadap penurunan kadar asam urat pada penderita asam urat di Dusun Kadisoro Desa Gilangharjo Kecamatan PandakKabupaten Bantul DIY.Metode: Penelitian ini merupakan penelitian eksperimental yaitu menilai pemberian air rebusan daun salam terhadap penurunan kadar asam urat dengan pendekatan Quasi Eksperiment Design dengan menggunakan Non Equivalent Control Group. Cara pengambilan sampel dalam penelitian ini adalah dengan teknik non probability sampling yaitu Purposive Sampling. Jumlah yang diperoleh 36 responden. Pemberian air rebusan daun salam selama 3 hari.Hasil:Berdasarkanhasil hasil uji Wilcoxon test statistics diperoleh nilai Asymp. Sig. sebesar 0,001 0,05 maka Ha diterima dan Ho ditolak yang artinya ada pengaruh pemberian air rebusan daun salam terhadap penurunan kadar asam urat pada penderita asam urat di Dusun Kadisoro Gilangharjo Pandak Bantul DIY.Kesimpulan :Berdasarkan hasil analisis mengenai pemberian air rebusan daun salam terhadap penurunan kadar asam urat pada penderita asam urat di Dusun Kadisoro Desa Gilangharjo Pandak Bantul DIY setelah meminum air rebusan daun salam mengalami penurunan kadar asam urat.
Pengaruh Penambahan Sari Buah Nanas (Ananas Comosus) terhadap Jumlah Bakteri Asam Laktat (BAL) dan Nilai pH Soyghurt
Authors: Wardani Emiliya Kusuma , Zulaekah Siti , Purwani Eni 
Published: October 2020

Penambahan sari buah nanas pada soyghurt dapat meningkatkan mutu organoleptik soyghurt. Sari buah nanas mengandung gula yang dapat meningkatkan aktivitas bakteri asam laktat (BAL). Sari buah nanas ditambahkan untuk memperbaiki citarasa soyghurt. Tujuan penelitian ini adalah untuk mengetahui pengaruh penambahan sari buah nanas terhadap jumlah bakteri asam laktat (BAL) dan nilai pH soyghurt. Penelitian dilakukan dengan konsentrasi sari buah nanas pada pembuatan soyghurt dengan variasi konsentrasi 0%, 15% dan 30%. Hasil penelitian menunjukkan bahwa tidak ada pengaruh penambahan sari buah nanas terhadap jumlah bakteri asam laktat (BAL) soyghurt dan kecenderungan adanya pengaruh penambahan sari buah nanas terhadap nilai pH soyghurt. Jumlah bakteri asam laktat (BAL) tertinggi diberikan oleh soyghurt dengan penambahan sari buah nanas pada konsentrasi 0% yaitu 2,88 x 14108" CFU/ml. Nilai pH tertinggi diberikan oleh soyghurt dengan penambahan sari buah nanas pada konsentrasi 0% yaitu 4,15.
STANDAR PENGATURAN PELINDUNGAN TEKNOLOGI SENSITIF KEANTARIKSAAN INTERNASIONAL: IMPLEMENTASI DI INDONESIA
Authors: Ardes Runggu Prilia 
Published: October 2020

ABSTRAKUndang-Undang Republik Indonesia Nomor 21 Tahun 2013 tentang Keantariksaan mengamanatkan Indonesia untuk menguasai teknologi keantariksaan secara mandiri. Namun, pemenuhan tujuan tersebut tidak mudah karena teknologi keantariksaan bersifat sensitif sehingga persebarannya dilindungi dan dibatasi oleh negara-negara maju. Wujud pelindungan tersebut adalah rezim pengendalian ekspor yang pada dasarnya bersifat soft law (hukum lunak), namun dalam penerapannya mengikat secara mutlak. Indonesia tengah menyusun sebuah Peraturan Pemerintah dengan harapan dapat meyakinkan negara-negara maju bahwa teknologi mereka akan aman di Indonesia. Tulisan ini hendak menganalisis bagaimana standar pengaturan pelindungan teknologi sensitif di negara-negara dan apakah ada kesenjangan antara praktik negara-negara dengan di Indonesia, dengan menggunakan metode perbandingan yaitu membandingkan peraturan di negara-negara (Uni Eropa dan Tiongkok) dengan peraturan Indonesia. Hasil analisis menunjukkan standar pengaturan pelindungan teknologi sensitif di negara-negara umumnya memuat (i) konsep pelindungan teknologi; (ii) penerapan rezim pengendalian ekspor internasional; (iii) daftar teknologi sensitif keantariksaan dan prinsip catch-all; (iv) perizinan dan penilaian; serta (v) pengawasan. Tulisan ini juga menemukan adanya kesenjangan antara standar tersebut dengan rancangan Peraturan Pemerintah di Indonesia.
Kata kunci: pelindungan teknologi; pengendalian ekspor; teknologi sensitif.
ABSTRACTLaw of the Republic of Indonesia Number 21 Year 2013 concerning Space Activities mandates Indonesia to master space technology independently. However, fulfilling these objectives is difficult because space technology is sensitive so that its distribution is protected and limited by developed countries. Such form of protection is export control regimes which is basically soft law but, in its application, is absolutely binding. Indonesia is currently drafting a Government Regulation in the hope of convincing developed countries that their technology will be safe in Indonesia. This paper intends to analyze how the standards for the regulation of the protection of sensitive technology in some States and whether there is a gap between such practices and in Indonesia, with comparative method which is comparing existing regulations in several States (European Union and China) with Indonesian regulations. The result of the analysis shows that the regulatory standards for sensitive technology protection in States generally consist of (i) the concept of technological protection; (ii) implementation of international export control regimes; (iii) list of space-sensitive technologies and the catch-all principle; (iv) licensing and assessment; and (v) supervision. This paper also finds gaps between these standards and the draft Government Regulation in Indonesia.
Keywords: export control; sensitive technology; technology protection.
DETERMINAN PROFITABILITAS BANK UMUM SYARIAH DI INDONESIA
Authors: MA Zuwardi , Padli Hardiansyah 
Published: October 2020

AbstrakProfitabilitas adalah kemampuan bank untuk menghasilkan laba secara efektif dan efisien. Jadi, penelitian ini bertujuan untuk menganalisis pengaruh efisiensi modal kerja (BOPO), rasio kecukupan modal (CAR), likuiditas (FDR) dan Inflasi terhadap profitabiltas yang tercermin dari Return On Asset (ROA) pada Bank Umum Syariah di Indonesia. Penelitian ini menggunakan data sekunder yang terdiri dari data bulanan dari tahun 2016-2018. Adapun metode analisis yang digunakan dalam penelitian ini metode Error Correction Model (ECM). Berdasarkan penelitian diperoleh hasil bahwa dalam jangka pendek BOPO berpengaruh secara signifikan dan negatif terhadap ROA. Sedangkan inflasi berpengaruh secara signifikan dan positif terhadap ROA. Sementara CAR dan FDR tidak berpengaruh secara signifikan terhadap ROA. Dalam jangka panjang BOPO berpengaruh negatif dan signifikan terhadap ROA. Sedangkan FDR dan inflasi berpengaruh signifikan dan positif terhadap ROA. dalam jangka panjang. CAR tidak berpengaruh signifikan terhadap ROA.Kata Kunci: BOPO, Inflasi, Profitabilitas AbstractProfitability is the ability of banks to generate profits effectively and efficiently. This study aims to analyze the effect of BOPO, Capital Adequacy Ratio (CAR), liquidity (FDR) and inflation on profitability reflected in Return on Assets (ROA) at Islamic Banks in Indonesia. This study used secondary data consisting of monthly data from 2016-2018. Data analysis used the Error Correction Model (ECM). Based on the research results obtained that BOPO has a significant and negative influence on ROA in the short term. While inflation has a significant and positive influence on ROA. In other hand, CAR and FDR do not significantly influence on ROA. In the long run, BOPO has a negative and significant effect on ROA. While FDR and inflation have a significant and positive effect on ROA. CAR has no significant influence on ROA.
Management of a recurrence of a squamous cell carcinoma of the scalp with extension to the brain: A case report and literature review
Authors: Chabaane Mohamed , Ayadi Khalil , Rkhami Mouna , Drissi Cyrine , Houimli Sarra , Bahri Kamel , Zammel Ihsen , Badri Mohamed 
Published: October 2020

Background:Squamous cell carcinoma (SCC) is the most common form of nonmelanoma skin cancer after basal cell carcinoma. Simple excision can be the treatment at early stages of diagnosis. However, at late stages, treatment is more complex due to extension to the skull and the dura. In extremely rare cases, it can invade the brain making it a challenging situation for treatment.Case Description:We present the case of a 54-year-old man with a history of cutaneous SCC who presented an invasive left frontal recurrence with brain invasion 19 years after initial surgery. The patient underwent surgery which consisted in tumor removal and bone and skin reconstruction. Immediate and late outcomes were favorable.Conclusion:Multidisciplinary treatment for SCC diagnosed in advanced stages is the best way to obtain encouraging results. Although significant advancements have been made, further study is needed for cases with advanced disease.
Moving Toward Third-Space: Reflections on the Tensions with/in Qualitative Research / Vers le troisième espace : réflexions sur les tensions en recherche qualitative
Authors: Klein Sheri R. 
Published: October 2020

Abstract: This reflective essay examines some of the dialectical tensions that can emerge within qualitative research and that can result in internal and external conflicts and a wide range of emotions and feelings for researchers. It is important to notice and examine these tensions as many art educators use qualitative research methods. Subsequently, more attention is needed to recognizing research as an emotional, and conflicted journey. The Japanese aesthetic of wabi-sabi and paradox theory offers applicable insights into the qualitative research process. Approaches to ‘qualitative thinking’ and artistic and contemplative methods are explored with the aim of reflexivity and disrupting dialectical thinking in qualitative research.Keywords: Qualitative research; Dialectical tensions; Third Space; Rhizomatic thinking. Résumé : Ce compte rendu réflexif se penche sur certaines des tensions dialectiques susceptibles d’apparaître en recherche qualitative, de mener à des conflits internes et externes et de susciter chez le chercheur une vaste gamme d’émotions et de sentiments. Il importe de prendre note de ces tensions et de s’y attarder car de nombreux éducateurs emploient concepts et méthodes de recherche qualitative. Il faut par conséquent se préoccuper davantage de la recherche qualitative en tant que processus émotionnel et souvent conflictuel. Cette enquête se base sur les travaux de chercheurs multidisciplinaires selon lesquels le concept « d’entre-deux » et de « troisième espace » perturbe fondamentalement la pensée binaire. D’autres stratégies sont par ailleurs introduites pour appuyer la pensée rationnelle dans le domaine de la recherche qualitative et la création de cultures de recherche rhizomatiques.Mots-clés : recherche qualitative, tensions dialectiques, troisième espace, pensée rhizomatique.