bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scalable, efficient, and secure RFID with elliptic curve cryptosystem for Internet of Things in healthcare environment
Authors: Noori Davood , Shakeri Hassan , Niazi Torshiz Masood 
Published: July 2020

AbstractThe rapid development of IoT technology has led to the usage of various devices in our daily life. Along with the ever-increasing rise of the Internet of Things, the use of appropriate methods for establishing secure communications in health care systems is vital. The adoption of high-security optimal mechanisms for this purpose has been more effective regarding the efficiency of medical information systems; hence, many studies are being conducted in this field today. One of the most important components is the RFID cards that can be used for communication between entities in the environment. In healthcare systems, patient information is critical and nobody should have access to this information. Thus, providing security for these networks is essential. Recently, good researches have been done in the area of authentication for medical information systems, using RFID technology, which has a low computational cost. In this paper, we propose a novel method based on elliptic curve cryptography for vital and efficient and scalable authentication between RFID cards, card readers, and servers. This proposed method maintains security and has less computational cost and low elliptic curve point multiplication running time compared to similar recent methods.
The existence and boundedness of linear and multilinear Marcinkiewicz integrals on central Campanato spaces
Authors: Ma Jiao , Wei Mingquan , Yan Dunyan 
Published: July 2020

AbstractIn this paper, we obtain the existence and boundedness of Marcinkiewicz integrals with homogeneous kernels on central Campanato spaces. Moreover, the existence and boundedness of multilinear Marcinkiewicz integrals on central Campanato spaces are also deduced. We extend various previous results to central Campanato spaces which can be seen as the local version of Campanato spaces.
A fuzzy inference system (FIS) to evaluate the security readiness of cloud service providers
Authors: Rizvi Syed , Mitchell John , Razaque Abdul , Rizvi Mohammad R. , Williams Iyonna 
Published: July 2020

AbstractCloud computing is a model for on-demand delivery of IT resources (e.g., servers, storage, databases, etc.) over the Internet with pay-as-you-go pricing. Although it provides numerous benefits to cloud service users (CSUs) such as flexibility, elasticity, scalability, and economies of scale, there is a large trust deficit between CSUs and cloud service providers (CSPs) that prevents the widespread adoption of this computing paradigm. While some businesses have slowly started adopting cloud computing with careful considerations, others are still reluctant to migrate toward it due to several data security and privacy issues. Therefore, the creation of a trust model that can evolve to reflect the true assessment of CSPs in terms of either a positive or a negative reputation as well as quantify trust level is of utmost importance to establish trust between CSUs and CSPs. In this paper, we propose a fuzzy-logic based approach that allows the CSUs to determine the most trustworthy CSPs. Specifically, we develop inference rules that will be applied in the fuzzy inference system (FIS) to provide a quantitative security index to the CSUs. One of the main advantages of the FIS is that it considers the uncertainties and ambiguities associated with measuring trust. Moreover, our proposed fuzzy-logic based trust model is not limited to the CSUs as it can be used by the CSPs to promote their services through self-evaluation. To demonstrate the effectiveness of our proposed fuzzy-based trust model, we present case studies where several CSPs are evaluated and ranked based on the security index.
Understanding the client characteristics of Aboriginal residential alcohol and other drug rehabilitation services in New South Wales, Australia
Authors: James Douglas B. , Lee KS Kylie , Patrao Tania , Courtney Ryan J. , Conigrave Katherine M. , Shakeshaft Anthony 
Published: July 2020

Abstract
Background
Aboriginal alcohol and other drug residential rehabilitation (residential rehabilitation) services have been providing treatment in Australia of over 50 years. However, there are no studies in Australia or internationally that document characteristics of clients attending Indigenous residential rehabilitation services worldwide. This is the first multi-site paper to describe key client characteristics of six Indigenous (hereafter Aboriginal Australians as the term recommended by the Aboriginal Health and Medical Research Council of New South Wales) residential rehabilitation services in Australia.

Methods
All recorded client admissions between 1 January 2011 to 31 December 2016 were considered from six operating services in the Australian state of New South Wales. Data collected were classified into categories based on demographics, treatment utilisation, substance use, mental health and quality of life characteristics. Means, median and percentages were calculated (where appropriate).

Results
There were 2645 admissions across the six services in the study period, with an average of 440 admissions per year across all services. Participants were aged between 26 to 35 years, with fewest participants aged 46 +. Program length ranged from 12 to 52 weeks (mean of 12 weeks). The completion rates and length of stay for each service ranged from less than two to more than 12 weeks. The principal drug of choice was alcohol and amphetamines in half of the services. Not all services used them, but a range of tools were used to measure treatment, substance use and mental health or quality of life outcomes.

Conclusion
This study is the first internationally to describe the key features of multiple Aboriginal residential rehabilitation services. The variation in tools used to collect client data made it difficult to compare client characteristics across services. Future research could explore predictors of treatment completion, identify opportunities for standardisation in client assessments and validate cultural approaches of care. These efforts would need to be guided by Aboriginal leadership in each service.
Integrated stepped alcohol treatment for patients with HIV and at-risk alcohol use: a randomized trial
Authors: Edelman E. Jennifer , Maisto Stephen A. , Hansen Nathan B. , Cutter Christopher J. , Dziura James , Deng Yanhong , Fiellin Lynn E. , O’Connor Patrick G. , Bedimo Roger , Gibert Cynthia L. , Marconi Vincent C. , Rimland David , Rodriguez-Barradas Maria C. , Simberkoff Michael S. , Tate Janet P. , Justice Amy C. , Bryant Kendall J. , Fiellin David A. 
Published: July 2020

Abstract
Background
At-risk levels of alcohol use threaten the health of patients with HIV (PWH), yet evidence-based strategies to decrease alcohol use and improve HIV-related outcomes in this population are lacking. We examined the effectiveness of integrated stepped alcohol treatment (ISAT) on alcohol use and HIV outcomes among PWH and at-risk alcohol use.

Methods
In this multi-site, randomized trial conducted between January 28, 2013 through July 14, 2017, we enrolled PWH and at-risk alcohol use [defined as alcohol consumption of ≥ 14 drinks per week or ≥ 4 drinks per occasion in men ≤ 65 years old or ≥ 7 drinks per week or ≥ 3 drinks per occasion in women or men > 65 years old]. ISAT (n = 46) involved: Step 1- Brief Negotiated Interview with telephone booster, Step 2- Motivational Enhancement Therapy, and Step 3- Addiction Physician Management. Treatment as usual (TAU) (n = 47) involved receipt of a health handout plus routine care. Analyses were conducted based on intention to treat principles.

Results
Despite a multi-pronged approach, we only recruited 37% of the target population (n = 93/254). Among ISAT participants, 50% advanced to Step 2, among whom 57% advanced to Step 3. Participants randomized to ISAT and TAU had no observed difference in drinks per week over the past 30 days at week 24 (primary outcome) [least square means (Ls mean) (95% CI) = 8.8 vs. 10.6; adjusted mean difference (AMD) (95% CI) =  − 0.4 (− 3.9, 3.0)].

Conclusion
An insufficient number of patients were interested in participating in the trial. Efforts to enhance motivation of PWH with at-risk alcohol use to engage in alcohol-related research and build upon ISAT are needed.
Trial registration Clinicaltrials.gov: NCT01410123, First posted August 4, 2011
What constitutes “behavioral health”? Perceptions of substance-related problems and their treatment in primary care
Authors: Chen Ida Q. , Chokron Garneau Helene , Seay-Morrison Timothy , Mahoney Megan R. , Filipowicz Heather , McGovern Mark P. 
Published: July 2020

Abstract
Background
Integrating behavioral health in primary care is a widespread endeavor. Yet rampant variation exists in models and approaches. One significant question is whether frontline providers perceive that behavioral health includes substance use. The current study examined front line providers’: 1. definition of behavioral health, and 2. levels of comfort treating patients who use alcohol and other drugs. Frontline providers at two primary care clinics were surveyed using a 28-item instrument designed to assess their comfort and knowledge of behavioral health, including substance use. Two questions from the Integrated Behavioral Health Staff Perceptions Survey pertaining to confidence in clinics’ ability to care for patients’ behavioral health needs and comfort dealing with patients with behavioral health needs were used for the purposes of this report. Participants also self-reported their clinic role. Responses to these two items were assessed and then compared across roles. Chi square estimates and analysis of variance tests were used to examine relationships between clinic roles and comfort of substance use care delivery.

Results
Physicians, nurses/nurse practitioners, medical assistants, and other staff (N = 59) participated. Forty-nine participants included substance use in their definition of behavioral health. Participants reported the least comfort caring for patients who use substances (M = 3.5, SD = 1.0) compared to those with mental health concerns (M = 4.1, SD = 0.7), chronic medical conditions (M = 4.2, SD = 0.7), and general health concerns (M = 4.2, SD = 0.7) (p < 0.001). Physicians (M = 3.0, SD = 0.7) reported significantly lower levels of comfort than medical assistants (M = 4.2, SD = 0.9) (p < 0.001) caring for patients who use substances.

Conclusions
In a small sample of key stakeholders from two primary care clinics who participated in this survey, most considered substance use part of the broad umbrella of behavioral health. Compared to other conditions, primary care providers reported being less comfortable addressing patients’ substance use. Level of comfort varied by role, where physicians were least comfortable, and medical assistants most comfortable.
Outcomes of wildlife translocations in protected areas: what is the type and extent of existing evidence? A systematic map protocol
Authors: Langridge Joseph , Sordello Romain , Reyjol Yorick 
Published: July 2020

Abstract
Background
Conversion, fragmentation, and loss of natural habitats are among the main causes of declining species’ populations worldwide. Protected areas are therefore crucial for biodiversity as they provide refuge and ensure key ecological processes. Wildlife translocations, defined as “the deliberate movement of organisms from one site for release in another”, have been used in conjunction as a conservation tool for a number of decades as wild populations become increasingly fragmented and endangered. Not only are translocations used to bolster the viability of imperiled species but are also recommended for improving population resilience and adapting species’ ranges in response to climate change. Despite translocation being a recognised conservation tool, it remains complex with variable results due to the different factors that can determine its success. Accordingly, the Map will investigate the existing evidence on the links between different types of wildlife translocation interventions and factors that may be important to consider for planning. This will provide an overview of relevant studies for possible future syntheses, and may help to inform management decisions.

Method
We will perform a thorough search of peer-reviewed journal articles and grey literature sources documenting the occurrence of translocations in the context of protected areas. Two databases will be used: Web of science core collection and Scopus, with a supplementary search in Google Scholar. Multiple key specialized websites will also be used. All bibliographic data will be extracted, managed, and screened in Microsoft excel. Three screening stages will be undertaken (title, then abstract, then full texts) against predefined inclusion criteria. The retained relevant literature will be subjected to coding and meta-data extraction. No formal validity appraisal will be undertaken. The Map will particularly highlight translocation operations in terms of origin and destination (i.e. translocating from one protected area to another, within the same area, and from and to non-protected areas) by taxonomic group, among other important factors (e.g. number of individuals, age class, release strategy, distance between capture and release sites etc.). Finally, a database will be provided along with a Map narratively describing the evidence with summary figures and tables of pertinent study characteristics.
Nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) among undocumented migrants and uninsured legal residents in Amsterdam, the Netherlands: a cross-sectional study
Authors: van Dulm E. , Klok S. , Boyd A. , Joore I. K. , Prins M. , van Dam A. P. , Tramper-Stranders G. A. , van Duijnhoven Y. T. H. P. 
Published: July 2020

Abstract
Background
Nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) is associated with an increased risk of infection. Colonization with MRSA is observed in < 1% of the general Dutch population. Increased risk for MRSA carriage is known to occur in several key groups, one of which is asylum seekers. However, little is known about MRSA carriage among undocumented migrants and uninsured legal residents. This study aimed to determine the prevalence of nasal MRSA carriage among these groups in Amsterdam, the Netherlands.

Methods
In this cross-sectional study, between October 2018 and October 2019, undocumented migrants and uninsured legal residents aged 18 years or older who were able to understand one of the study languages were recruited at an NGO health care facility in Amsterdam, the Netherlands, for general practitioner (GP) consultations. Participants were asked questions on demographics, migration history, antibiotic use and other possible risk factors for MRSA carriage and were screened for nasal MRSA carriage by selective culturing e-swabs. Characteristics of MRSA-negative and MRSA-positive participants were compared using univariable logistic regression analysis with Firth’s correction.

Results
Of the 3822 eligible patients, 760 were screened for nasal MRSA carriage (19.9%). Of the 760 participants, over half were male (58%; 442/760) and originated mainly from Africa (35%; 267/760), Asia (30%; 229/760) and North or South America (30%; 227/760). In total, 705/760 participants (93%) were undocumented migrants and 55/760 (7%) were uninsured legal residents of Amsterdam. The overall prevalence of nasal MRSA carriage was 2.0% (15/760) (95%CI 1.1 to 3.2%), with no difference between undocumented migrants (14/705) (2.0, 95%CI 1.1 to 3.3%) and uninsured legal residents (1/55) (1.8, 95%CI 0.1 to 9.7%). Genotyping showed no clustering of the 15 isolates. MRSA carriage was not associated with sociodemographic, migration history or other possible risk factors. Nevertheless, this study had limited power to detect significant determinants. Three participants (3/15; 20%) harbored Panton-Valentine leukocidin (PVL)-positive isolates.

Conclusion
Even though our study population of undocumented migrants and uninsured legal residents had a higher prevalence of nasal MRSA carriage compared to the general Dutch population, the prevalence was relatively low compared to acknowledged other high-risk groups.
A preclinical animal model for evaluating the sealing capacity of covered stent grafts in acute vessel perforation
Authors: Öner Alper , Moerke Caroline , Wolff Anne , Kischkel Sabine , Schmidt Wolfram , Grabow Niels , Ince Hüseyin 
Published: July 2020

Abstract
Background
Percutaneous coronary intervention is among the most common therapeutic interventions in cardiology. This procedure may, however, be associated with a rare, though life-threatening complication: acute coronary perforation (CP). CP is primarily treated using covered stents, which are made of bare metal stents with a polytetrafluoroethylene (PTFE) or polyurethane coating. These stents’ major limitations include higher rates of thrombus formation and restenosis. Hence, there is a still unmet need for new stents regarding their design and composition. Or, to test new covered stent designs, the rabbit iliac artery has become the best-established animal model. This study sought to present a preclinical animal approach designed to test covered stents that are utilized following vessel perforation.

Methods
The animal experiments were performed using New Zealand white rabbits, each weighting 3.5–4.5 kg. The animal models described herein relied on the three most common clinical causes for CP, such as guidewire-induced, balloon catheter bursting, and device oversizing. Moreover, the sealing capacity of covered stent grafts was assessed for each of these models by means of angiography.

Results
We herein report a rabbit iliac artery perforation model using three different types of vessel perforation that closely mimic the clinical setting, such as guidewire-induced, balloon catheter rupture, and device oversizing. Using the same rabbit iliac perforation model, we additionally assessed the sealing capacity of a covered stent graft for each model.

Conclusions
The novel rabbit iliac artery perforation models, as described in this report, represent promising animal testing approaches. While their setting is very similar to the real-life context encountered in humans, all three models are based on an animal model that is ideally suited for evaluating the sealing capacity and performance of new medical devices for humans.
Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease
Authors: Mezö Charlotte , Dokalis Nikolaos , Mossad Omar , Staszewski Ori , Neuber Jana , Yilmaz Bahtiyar , Schnepf Daniel , de Agüero Mercedes Gomez , Ganal-Vonarburg Stephanie C. , Macpherson Andrew J. , Meyer-Luehmann Melanie , Staeheli Peter , Blank Thomas , Prinz Marco , Erny Daniel 
Published: July 2020

AbstractIt was recently revealed that gut microbiota promote amyloid-beta (Aβ) burden in mouse models of Alzheimer’s disease (AD). However, the underlying mechanisms when using either germ-free (GF) housing conditions or treatments with antibiotics (ABX) remained unknown. In this study, we show that GF and ABX-treated 5x familial AD (5xFAD) mice developed attenuated hippocampal Aβ pathology and associated neuronal loss, and thereby delayed disease-related memory deficits. While Aβ production remained unaffected in both GF and ABX-treated 5xFAD mice, we noticed in GF 5xFAD mice enhanced microglial Aβ uptake at early stages of the disease compared to ABX-treated 5xFAD mice. Furthermore, RNA-sequencing of hippocampal microglia from SPF, GF and ABX-treated 5xFAD mice revealed distinct microbiota-dependent gene expression profiles associated with phagocytosis and altered microglial activation states. Taken together, we observed that constitutive or induced microbiota modulation in 5xFAD mice differentially controls microglial Aβ clearance mechanisms preventing neurodegeneration and cognitive deficits.
Simulation of uniaxial stress–strain response of 3D-printed polylactic acid by nonlinear finite element analysis
Authors: Alharbi Mohammed , Kong Ing , Patel Vipulkumar Ishvarbhai 
Published: July 2020

AbstractAccurate simulation of mechanical properties of 3D-printed objects can provide critical inputs to designers and manufacturers. Polylactic acid, a biodegradable polymer, is particularly important in this regard due to its excellent print quality and a wide range of applications. Herein, an accurate uniaxial stress–strain profile simulation of 3D-printed PLA is reported. Nonlinear Finite Element Analysis (FEA) was used to simulate the uniaxial tensile test and build a material model for the prediction of the stress–strain response. 3D model for this nonlinear FEA study was built in SolidWorks, and several measures were taken to simulate the nonlinear stress–strain response with high accuracy. Von Mises stress, resultant displacement, and strain plots were produced. Comparison with experimental data extracted from the literature was done to validate the FEA model. Fracture behavior was predicted by FEA stress distribution. Deviations between the stress–strain plot obtained by FEA from the experimentally obtained plot were minimal. The entire curve, except the failure zone, could be precisely simulated. Furthermore, the developed von Mises plasticity material model and the boundary conditions also captured the behavior of specimen under uniaxial tension load and the deviation between experimental results was minor. These results suggest that the developed material model could be useful in non-linear FEA studies on 3D printed PLA objects which are expected to withstand tensile stress.
Sensory stimulation in the treatment of children with sleep-related rhythmic movement disorder: a feasibility and acceptability study
Authors: van Sluijs Rachel M. , Wilhelm Elisabeth , Rondei Quincy J. , Jäger Lukas , Gall Markus , Garn Heinrich , Achermann Peter , Jenni Oskar G. , Riener Robert , Hill Catherine M. 
Published: July 2020

Abstract
Background
Sleep-related rhythmic movement disorder is characterized by repetitive gross-motor movements at sleep onset or during sleep, which result in clinical consequences such as impact on daytime functioning and injury. No well-established therapies exist today. Substituting the patient’s movements with external sensory stimulation may offer a treatment modality. The aim of the current study was to test the feasibility and acceptability of vestibular stimulation using a rocking bed (Somnomat) in children with rhythmic movement disorder and to assess children’s movement preference.

Methods
Children with rhythmic movement disorder (n = 6, Age: 5–14 years) were studied over three nights in a sleep laboratory: adaptation night (normal bed) and randomised-order baseline (Somnomat) and intervention nights (Somnomat). Child’s preferred movement direction (head-to-toe or side-to-side) and frequency (between 0.25 and 2 Hz), determined during an afternoon protocol, were applied using the Somnomat for 1 h after lights out, and in response to subsequent episodes of rhythmic movement during intervention nights. Comfort assessed using a questionnaire, and objective sleep parameters assessed using videosomnography, were compared.

Results
The participants’ sometimes violent rhythmic movements did not disturb device performance. All children rated intervention nights equally or more comfortable than baseline nights. Self-reported sleep quality, as well as the number and duration of movement episodes did not significantly differ between baseline and intervention nights.

Conclusions
Providing rocking movements using the Somnomat is both technically feasible and acceptable to the target population. The therapeutic value of this novel stimulus substitution for rhythmic movement disorder should now be evaluated in a larger sample over a longer period in the home setting.

Trial registration
The trial was retrospectively registered at clinicaltrials.gov (NCT03528096) on May 17th 2018.