bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative analysis of physicochemical, rheological, sensory and flavour properties of yoghurts using a new probiotic Bacillus coagulans 13002 with traditional yoghurt starter
Authors: Zhao Shan , Zhou Qin‐yu , Huang Yan‐yan , Nan Shu‐gang , Liu Dong‐mei 
Published: September 2020

SummaryBacillus coagulans 13002 (13002) as a new potential starter was incorporated into the yoghurts for fermentation in this study. We compared three groups of yoghurt, including Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus (SL), 13002 (BCS), and 13002 and SL (BCS + SL). Compared with the combination of SL and BCS, the group of BCS + SL exhibited better flavour, higher titratable acidity, cohesiveness and richer volatile compounds, suggesting that the combination of BCS and SL was more efficient to produce the best sensory properties of yoghurt (P < 0.05). The production of volatile compounds in fermentation with and without the addition of BCS was mainly affected by aldehydes, ketones, esters and hydrocarbons, respectively. Furthermore, BCS additions into traditional starters resulted in increasing organic acids and speeding up the usage of sucrose and lactose during the fermentation period of yoghurt. Our study suggested that BCS is a favourable starter supplement for improving the quality of probiotic yoghurts.
Development of low‐fat chicken bologna sausages enriched with inulin, oat fibre or psyllium
Authors: Ferjančič Blaž , Kugler Saša , Korošec Mojca , Polak Tomaž , Bertoncelj Jasna 
Published: September 2020

SummaryGrowing demand for healthy meat products and the contemporary focus on the role of dietary fibre in nutrition have resulted in the development of reformulated meat products. This study investigated the enrichment of chicken bologna type sausages with 3% and 6% inulin, oat fibre or psyllium, while decreasing the fat content. Enrichment with 3% inulin or oat fibre was most suitable due to the comparable colour (a*: 10.96 vs. 10.16 for control, b*: 9.28 vs. 8.94 for control), texture parameters (adhesiveness: 0.26 N vs. 0.38 N for control, gumminess: 55.51N vs. 54.74 N for control, cohesiveness: 0.72 vs. 0.70 for control, hardness: 77.45 N vs. 78.03 N for control, springiness 0.94 vs. 0.93 for control, resilience: 0.39 vs. 0.37 for control, chewiness: 52.16 N vs. 50.93 N for control) and sensory properties to the control. Psyllium was less suitable regardless of the amount added to the bologna type chicken sausages. Enrichment with 6% dietary fibre had negative effects on the instrumental and sensory parameters. Sensory evaluation by consumers showed comparable acceptability for chicken bologna type sausages enriched with 3% inulin or oat fibre; however, sausages enriched with psyllium or 6% inulin or oat fibre were less acceptable.
The Sysmex XN‐L (XN‐350) hematology analyzer offers a compact solution for laboratories in niche diagnostics
Authors: Khartabil Tania A. , de Frankrijker Magda M. , de Rijke Yolanda B. , Russcher Henk 
Published: September 2020

AbstractIntroductionIn 2015, Sysmex launched a new series of hematology analyzers (XN‐L Series) designed to fulfill the needs of niche laboratories in areas such as pediatrics, dialysis, neurology, and oncology while providing a compact solution. In this study, we evaluate the whole blood and body fluid modes of one of these analyzers, the XN‐350.MethodsA total of 300 residual EDTA samples were measured on the XN‐350 in whole blood mode and the XN‐1000 to evaluate method comparison, flagging sensitivity, repeatability, reproducibility, linearity, carryover, and stability. In addition, 191 samples were obtained and processed in body fluid mode which included, cerebrospinal fluid (CSF), continuous ambulatory peritoneal dialysis (CAPD), ascites, synovial, and pleural fluid to perform method comparison, repeatability, reproducibility, linearity, limit of quantitation, and carryover studies.ResultsStrong agreement was shown between the XN‐350 and XN‐1000 for both whole blood and body fluid modes in results and flagging. Linearity results in both modes on the XN‐350 showed a high R2 value (>.99). For WBC, RBC, HGB, and PLT, the carryover results were well within the predetermined criteria of ≤0.5% for whole blood and ≤0.3% for CSF. Repeatability and reproducibility were acceptable for both modes, and there were no significant deviations present in stability for whole blood. In addition, there was high agreement in all body fluid types evaluated.ConclusionThe performance of the XN‐350 is comparable to the XN‐1000 in both whole blood and body fluid modes, making it a reliable alternative to larger analyzers for smaller, niche laboratories.
The roles of temperamental inhibition in affective and cognitive empathy in Chinese toddlers
Authors: Zhai Shuyi , Lu Chenxin , Han Jinjing , Du Shuiyun , Wu Weiyang , He Jie 
Published: September 2020

AbstractEmpathy, crucial to harmonious interpersonal relationships and moral development, has both affective and cognitive components. Previous studies found that toddlers’ temperamental inhibition may influence their empathy, but mainly focused on emotional response to others’ distress. Little is known about whether inhibited children's poor empathy is due to high reactivity and social withdrawal when sharing others’ affective states, such as distress (affective empathy), or to a difficulty in comprehending and inferring others’ perspective (cognitive empathy). The current study investigated the role of behavioral inhibition (BI) in affective empathy (response to pain simulation) and cognitive empathy (performance in perspective‐taking task) among 163 Chinese toddlers and tested in both only and non‐only children. Correlation analyses showed that BI was only negatively associated with affective empathy. The relation between BI and cognitive empathy was moderated by self‐regulation and inhibited children who were low in self‐regulation presented low cognitive empathy. Additionally, only children presented advanced cognitive empathy but poorer affective empathy than non‐only children. These findings imply different roles of BI in affective versus cognitive empathy in early childhood. Although highly inhibited children rarely show positive social expression toward others’ distress, caution is needed in inferring that they lack a capacity for cognitive empathy.
Online consultation and emergency management in paediatric dentistry during the COVID‐19 epidemic in Wuhan: A retrospective study
Authors: Yang Fengjiao , Yu Lintong , Qin Danchen , Hua Fang , Song Guangtai 
Published: September 2020

AbstractBackgroundThe COVID‐19 pandemic posed a great challenge to paediatric dentistry, which confronted with the restriction of service and resource shortage.AimTo retrospectively analyse the information of children's dental online health consultation during the COVID‐19 pandemic in China, and to provide methods to distinguish between dental emergencies and non‐emergencies as well as their management.DesignWe collected all the online consultation information in Dept. of Paediatric dentistry, School & Hospital of Stomatology, Wuhan University, from 2 February to 31 March 2020, and extracted the information of age, gender, reason for consultation, description of symptom, and preliminary diagnosis of the children.ResultsA total of 474 online consultations of paediatric dentistry were included within 59 days during lockdown, and 190 (40.1%) were dental emergencies and 284 (59.9%) non‐emergencies. Of 190 emergency consultations, 186 (97.9%) showed swelling, pain, and trauma with or without systemic symptoms. Among 284 non‐emergency consultations, retained primary teeth (n = 126) and orthodontic consultation (n = 53) were the most common reasons for consultation.ConclusionThe paediatric emergency and non‐emergency problems should be clearly distinguished and sufficient instructions provided in the special period of COVID‐19. Priorities also should be set to deal with urgent conditions after the release of lockdown.
Pathways to anterior open bite after changing of pacifier sucking habit in preschool children: A cohort study
Authors: Moraes Renita Baldo , Knorst Jessica Klöckner , Pfeifer Alana Beatriz Redel , Vargas‐Ferreira Fabiana , Ardenghi Thiago Machado 
Published: September 2020

AbstractBackgroundPacifier use is a major cause of anterior open bite (AOB), which negatively impacts the quality of life of children affected.AimTo assess the direct and indirect pathways related to pacifier sucking habit and AOB in preschool children.DesignThis 2‐year cohort study evaluated a random sample of preschool children (2‐5 years of age) from Southern Brazil. Caregivers answered a questionnaire addressing socio‐economic and behavioural characteristics. Anterior open bite was recorded following the criteria recommended by Foster and Hamilton. Structural equation model was performed to assess the direct and indirect pathways among variables at baseline (T1) to predict the AOB at follow‐up (T2).ResultsRegarding the AOB, 407 children were evaluated at T1 and 187 at T2. The prevalence of AOB was 32.9% at baseline and 16.0% at follow‐up. The presence of AOB at follow‐up was directly affected by the change in pacifier sucking habit from T1 to T2. Considering the indirect paths, the AOB at T1 influenced the AOB in T2 via a change of pacifier sucking habit.ConclusionThese findings suggest that the non‐habit of sucking pacifiers is a fundamental strategy for the prevention of AOB as well as the promotion of health in childhood.
Atomic and micro‐structure features of nanoporous aluminosilicate glasses from reactive molecular dynamics simulations
Authors: Mahadevan Thiruvilla S. , Du Jincheng 
Published: September 2020

AbstractLong‐term chemical durability of borosilicate glasses that makes them a widely accepted form of nuclear waste disposal is achieved through the formation of a porous aluminosilicate gel layer that provides passivity and limits the transport of water to the reaction front. Detailed understanding of the porous silicate gel layer is thus critical in elucidating the corrosion mechanism of these glasses and to design of new glass composition for waste immobilization and other applications. In this paper, we use the diffuse charge reactive potential to generate porous aluminosilicate glass structures with compositions equivalent to the gel layers formed at the glass‐water interface with an aim to understand the processing condition on the microstructure and atomic structure of these systems. We demonstrate the use of the charge scaling techniques is an effective approach to generate these porous structures with controllable pore mophologies. After initial validation of the potentials and calcium aluminosilicate glass structures using neutron diffraction, we created gel structures with compositions similar to well‐known model nuclear waste borosilicate glasses. The porosities and the pore size distribution bear a strong correlation to the processing temperature, as well as to the local atomic structure. Thus, by controlling the processing parameters, the generated porous structures can be customized to closely resemble gel structures due to borosilicate glass corrosion. These results provide insights of the micro‐ and atomic structure features of the porous aluminosilicate glasses and on the optimal procedure to generate porous structures that can be comparable to experimentally observed gel layer structures thus to elaborate on the correlations between the structure and phenomena in glass‐water interactions.
Development and validation of an instrument to assess work support needs of adults with intellectual disabilities in sheltered employment
Authors: Wong Shyh Shin , Ong Kuei Rong , Teo Clara Hui Xin , Ng Jing Yi , Gwee Ai Jia , Toh Alison Yiling 
Published: September 2020

AbstractBackgroundThe Work Support Profile (WSP) is a brief assessment instrument that enables staff supporting adults with disabilities to provide calibrated and individualized support for specific work tasks. This paper sought to examine the psychometric properties of WSP for people with disabilities.MethodA pilot study was conducted with 239 sheltered workshop employees diagnosed mainly with intellectual disability to explore the structure of this assessment tool, and provide initial evidence of its psychometric properties. Subsequently, a larger‐scale study captured a nationwide profile of 761 sheltered workshop employees with intellectual disability.ResultsAcross both studies, factor analyses yielded a conceptually acceptable 5‐factor structure with 33 items accounting for approximately 65% of the variance. Furthermore, the reliability, convergent and discriminant validity of WSP can be considered adequate.ConclusionResults provide preliminary evidence that WSP is a psychometrically adequate tool for assessing the work support needs of adults with disabilities on given work tasks.
STAT3 isoforms differentially affect ACE2 expression: A potential target for COVID‐19 therapy
Authors: Shamir Inbal , Abutbul‐Amitai Mor , Abbas‐Egbariya Haya , Pasmanik‐Chor Metsada , Paret Gideon , Nevo‐Caspi Yael 
Published: September 2020

AbstractThe SARS‐coronavirus 2 is the aetiologic agent COVID‐19. ACE2 has been identified as a cell entry receptor for the virus. Therefore, trying to understand how the gene is controlled has become a major goal. We silenced the expression of STAT3α and STAT3β, and found that while silencing STAT3α causes an increase in ACE2 expression, silencing STAT3β causes the opposite effect. Studying the role of STAT3 in ACE2 expression will shed light on the molecular events that contribute to the progression of the disease and that the different roles of STAT3α and STAT3β in that context must be taken in consideration. Our results place STAT3 in line with additional potential therapeutic targets for treating COVID‐19 patients.
Empowering nurses and residents to improve telemetry stewardship in the academic care setting
Authors: Duffy Eamon , Niessen Timothy , Perrin Keisha , Apfel Ariella , Bertram Amanda , Keller Sara C. , Feldman Leonard S. , Pahwa Amit K. 
Published: September 2020

AbstractAims and ObjectivesInappropriate use of telemetry frequently occurs in the inpatient, non‐intensive care unit setting. Telemetry practice standards have attempted to guide appropriate use and limit the overuse of this important resource with limited success. Clinical‐effectiveness studies have thus far not included care settings in which resident‐physicians are the primary caregivers.MethodsWe implemented two interventions on general internal medicine units of an academic hospital. The first intervention, or nurse‐discontinuation protocol, allowed nurses to trigger the discontinuation of telemetry once the appropriate duration had passed according to practice standards. The second intervention, or physician‐discontinuation protocol, instituted a best‐practice advisory that notified the resident‐physician via the electronic medical record when the appropriate telemetry duration for each patient had elapsed and suggested termination of telemetry. Data collection spanned 8 months following the implementation of the nurse‐discontinuation protocol and 12 months following the physician‐discontinuation protocol.ResultsDuring the control period, the average time spent on telemetry was 86.29 hours/patient/month. During the nurse‐discontinuation protocol, patients spent, on average, 70.86 hours/patient/month on telemetry. During the physician‐discontinuation protocol, patients spent, on average, 81.6 hours/patient/month on telemetry. During the nurse‐discontinuation protocol, there was no significant change in the likelihood that a patient was placed on telemetry throughout their admission when compared with the control period. During the physician‐discontinuation protocol, there was a significant decrease of 56.1% in the likelihood that a patient would be put on telemetry when compared with the control time period.ConclusionsThese findings expand our understanding of telemetry use in the academic care setting in which trainees serve as the primary caregivers. Furthermore, these findings represent an important addition to the telemetry and patient monitoring literature by demonstrating the impact that nurse‐managed protocols can have on telemetry use and by highlighting effective strategies to improve telemetry use by physicians in training.
Allogeneic cortical struts and bone granules for challenging alveolar reconstructions: An innovative approach toward an established technique
Authors: Würdinger Robert , Donkiewicz Phil 
Published: September 2020

AbstractObjectiveThe shell technique is a well‐established procedure for GBR with which extensive osseous defects can be predictably restored by using cortical bone struts harvested from various intraoral aspects. Recent publications have demonstrated comparable results for autologous and allogeneic bone grafts, whereas the evidence on allogeneic cortical struts remains limited.Clinical considerationsIn this case series, we demonstrate the regeneration of five complex alveolar bone defects in four patients with subsequent insertion of fixed dental implants. In all cases, cortical struts made from human donor bone were applied in combination with allogeneic bone granules and collagen membranes.ConclusionsSimilar to autologous cortical shells, the allogeneic struts functioned by creating an immobile container with which the osseous defects in all patients could be successfully restored, enabling placement of dental implants in accordance with the treatment plan. Even when the containers were solely filled with allogeneic granules, vascularized healthy tissue was present at re‐entry, demonstrating the vast potential of these materials for applications in dentistry.Clinical significanceEspecially when it comes to regeneration of complex alveolar bone defects, autologous bone grafts are often outlined as the only treatment modality. Here we show that innovative biomaterials like allogeneic bone grafts hold the potential to mimic the functions of autologous bone transplants and provide excellent clinical results without the requirement of a second surgical side for bone harvesting and no risk of donor‐site morbidity.
A novel carbamide peroxide polymeric nanoparticle bleaching gel: Color change and hydrogen peroxide penetration inside the pulp cavity
Authors: Favoreto Michael W. , Madureira Mariniella P. , Hass Viviane , Maran Bianca M. , Parreiras Sibelli O. , Borges Christiane P. F. , Reis Alessandra , Loguercio Alessandro D. 
Published: September 2020

AbstractObjectiveThis study evaluated the hydrogen peroxide (HP) penetration inside the pulp cavity and the color change of teeth submitted to the 15% carbamide peroxide (CP) nanoparticle bleaching gel at several application times.Materials and methodsPremolars were divided into nine groups (n = 6) according to 15% CP bleaching agents (nanoparticle and commercial) and to application times (15, 30, 45, and 60 minutes). A negative control was exposed to ultra‐purified water. After a whitening procedure, the HP concentration (μg/mL) inside the pulp cavity was assessed via spectrophotometry. The color change (ΔE* and ΔE00*) was evaluated with a spectrophotometer. Data were analyzed via two‐way ANOVA and Tukey (α = 0.05).ResultsA lower concentration of HP was detected for CP nanoparticle gel after 30 and 45 minutes of whitening procedure (P = .001). The bleaching groups promoted a higher color change (ΔE* and ΔE00*) regardless of the application time (P = .0001).ConclusionsThe CP nanoparticle gel reduced HP inside the pulp cavity, and showed effective bleaching compared with CP commercial gel.Clinical significanceUsing 15% carbamide peroxide nanoparticle bleaching gel decreased the HP penetration inside the pulp cavity and may decrease bleaching‐induced tooth sensitivity in at‐home bleaching.
Fracture load of CAD/CAM ultrathin occlusal veneers luted to enamel or dentin
Authors: Valenzuela Eneida Beatriz Sanfelice , Andrade Jonas Pereira , da Cunha Patrícia Fernandes Jerzewski Sotero , Bittencourt Hélio Radke , Spohr Ana Maria 
Published: September 2020

AbstractObjectivesTo evaluate, in vitro, the fracture load of IPS e.max CAD occlusal veneers at thicknesses of either 0.3 or 0.6 mm luted to enamel or dentin.Materials and methodsFifty human molars were randomly distributed into five groups (n = 10): G1 ‐ healthy teeth (control); G2‐0.3‐mm‐thick veneers luted to enamel; G3‐0.6‐mm‐thick veneers luted to enamel; G4‐0.3‐mm‐thick veneers luted to dentin; and G5‐0.6‐mm‐thick veneers luted to dentin. After the luting procedures, the specimens were immersed in distilled water at 37°C for 24 hours and then subjected to mechanical loading (106 cycles at 200 N load). The specimens were subjected to a fracture load test in a universal testing machine. Two‐way ANOVA and Tukey's test (α = 0.05) were used to analyze data.ResultsOnly the thickness factor was significant (P = .002). Values of fracture load followed by distinct letters represent significant differences (P < .05): G1 (3204 N ± 730)ab; G2 (3144 N ± 729)ab; G3 (2489 N ± 606)b; G4 (3591 N ± 776)a; and G5 (2770 N ± 598)ab.ConclusionIPS e.max ultrathin occlusal veneers luted to enamel or dentin obtained fracture load comparable to that of the healthy tooth.Clinical significanceIPS e.max CAD ultrathin occlusal veneers at 0.3 or 0.6‐mm‐thick seem to provide good perspectives in relation to the clinical use.
Multi‐objective optimization of mechanical oil extraction fromCamellia oleiferaseeds using Kriging regression andNSGA‐II
Authors: Huang Shuai , Hu Youmin , Li Fengcheng , Jin Wenwen , Wu Bo 
Published: September 2020

AbstractThe objective of this study is to optimize the mechanical extraction process of crude camellia oil regarding yield and quality. The effects of process parameters namely applied pressure (10–45 MPa), heating temperature (40–100°C), heating time (10–40 min), and moisture content (0–9%) on oil yield, free fatty acid (FFA), and peroxide value (PV) were investigated by modeling the oil extraction process using Kriging regression (KR) models; optimum process parameters were then determined via non‐dominated sorting genetic algorithm II (NSGA‐II). The results showed that KR model is effective to predict the yield (R2= 0.9595 and A‐RMSE = 1.94), FFA (R2= 0.9983 and A‐RMSE = 0.0517), and PV (R2= 0.8733 and A‐RMSE = 0.0358). The relationship between process parameters and each objective is non‐linear. In addition, the maximum yield (42.20%) and best quality parameters (minimum FFA = 0.2917 KOH mg/g and minimum PV = 0.1316 g/100 g) are contradictory, which suggested applying Pareto‐optimal front to balance the three objectives to a satisfied degree.Practical ApplicationsHeating temperature, applied pressure, heating time and moisture content are primary operating conditions affecting the yield and quality of mechanically extracted fats and oil. Selecting the suitable values of these parameters can therefore improve the oil yield and oil quality. This could be realized by process optimization based on experimental and mathematical modeling method. The KR model and NSGA‐II were, therefore, adopted to optimize the process parameters to obtain maximum yield, minimum FFA and PV. In addition, parametric analysis was conducted to give insight into the effects of process parameters on the yield and quality, which is beneficial to understand the mechanism behind the mechanical extraction of camellia oil. The Pareto‐optimal front obtained from NSGA‐II provides engineers with several decision parameters to design the equipment and to obtain better end products more efficiently.