bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applications
Authors: Subashini K , Prakash S , Sujatha V 
Published: November 2020

Abstract
The new hydrogel network was prepared by using glutaric acid, ethylene glycol and acrylic acid (GEA) through condensation polymerization without cross linker and it was fabricated by incorporation of green synthesized CuO nanoparticles (CuO NPs). The CuO NPs were synthesized by green route using Sterculia foetida leaf aqueous extract. Green synthesized CuO NPs were incorporated with GEA hydrogel resultant the GEA-CuO nanocomposite. The formation of green synthesized CuO NPs and GEA-CuO nanocomposite was confirmed by UV-Visible and FT-IR spectrum. The structure of GEA hydrogel was determined by 1H and 13C NMR technique. Morphology of synthesized GEA hydrogel and GEA-CuO nanocomposite was observed as bulged layer and uneven plates with cavities in SEM analysis, moreover the size of the material was evaluated by TEM analysis. Thermogravimetric analysis has revealed the GEA-CuO nanocomposite owing significantly higher thermal stability than raw GEA hydrogel. However, biological effect of synthesized GEA hydrogel and GEA-CuO nanocomposite was scrutinized by antibacterial activity against selected bacterial organisms and anticancer activity against lung cancer cell line A549.
Investigation into electrochemical performance of NiO/graphene composite nanofibers synthesized by a simple method as anode materials for high-performance lithium ion batteries
Authors: Yuan Baige , Li Jun , Xia Manman , Zhang Ying , Lei Ruyan , Zhao Peng , Li Xiao 
Published: November 2020

Abstract
The NiO/graphene (NiO/G) composite nanofibers were successfully synthesized by simple electrospinning followed by heat treatment. They as anode materials for lithium ion batteries demonstrated the more outstanding electrochemical performance when compared with the NiO + Ni composite nanofibers as the reference. NiO/G exhibited a higher discharging/charging capacity (about 712 mAh·g−1 at the third cycle) with a coulombic efficiency of nearly 100% than NiO + Ni (547 mAh·g−1). NiO/G also demonstrated the excellent cycling stability due to its higher discharging capacity of 571 mAh·g−1 and retention rate of 78% than NiO + Ni (184 mAh·g−1 and 33%) when subject to 50 cycles at 100 mA·g−1. Moreover, its rate performance was also greatly improved when compared with NiO + Ni owing to its higher discharging capacity (305 mAh·g−1, 556 mAh·g−1) and retention rate (44%, 80%) at the current density increased from 100 mA·g−1 to 2000 mA·g−1, and then recovered to 100 mA·g−1. The outstanding electrochemical performance of the NiO/G electrode is closely related to its lower ohmic resistance (2.1 Ω)/charge transfer resistance (86.5 Ω), and stronger diffusion capability of Li+ resulting from the high specific surface area, excellent conductivity and a certain charge storage capacity of graphene.
Type-II band alignment in single crystalline TiO2 nanowires under twisting
Authors: Liu Zhao , Zhang Dong-Bo 
Published: November 2020

Abstract
Electronic structures with the type-II band alignment usually exist only in heterostructures. Using the generalized Bloch theorem, we reveal that an effective type-II band alignment can be induced in the single crystalline TiO2 nanowires (NWs) by an axial twisting deformation. With this, we further reveal distinct responses of the the valence band (VB) states and the conduction band (CB) states in the radial dimension of the nanowire. Specifically, in the twisted NW, the VB states migrate from the NW core toward the NW shell while the CB states migrate from the NW shell toward the NW core. Our results pave a new way to realize the type-II band alignment in single crystalline NWs, which is critical for actual applications such as NW-based photovoltaic effect and photocatalytic effect. Further, the significant variation of the quantum states also illustrates the possibility to tune the electronic properties of TiO2 NWs by strain engineering.
The impact of process parameters on surface roughness and bushing in friction drilling
Authors: N Narayana Moorthy , Kanish T C 
Published: November 2020

Abstract
Friction drilling is considered a non-traditional hole making method in which the workpiece is penetrated by a conical rotating instrument and a bush is formed without producing chips in a single cycle. In the present work, using a CNC milling machine, the friction drilling process was carried out on Be-Cu C17200 plate material. The process parameters such as spindle speed and feed rate were performed over three levels of workpiece material thickness. Surface roughness, bush length, and the thrust force of the drilled holes were analysed following drilling. For optimal surface roughness and bush formation, it is noted that spindle speed and feed rate play a significant role in friction drilling. Higher feed rate and thrust force have a direct effect on greater roughness of the surface and increased bush length. Better bushing and surface roughness are given by an increase in spindle speed.
Science Fictionality and Post-65 Asian American Literature
Authors: Fan Christopher T 
Published: November 2020

AbstractSince 1965, Asian American authors have been key mediators of science fictionality, defined as a postwar fantasy that associates endless, industrial-led economic expansion with racialized groups of upwardly mobile professionals. This status is a consequence of the occupational concentration of Asian immigrants into professional-managerial careers, especially in scientific and technical fields: a phenomenon that can be traced back to the 1965 Immigration and Nationality Act. Reading Maxine Hong Kingston’s Woman Warrior (1976) along with the debut works of recent Chinese American women writers, including Ling Ma’s Severance (2018), this article describes a dialectic of science fictionality and post-65 Asian American literature in which the latter develops autopoetic tendencies that register occupational concentration in genre, theme, characterization, and trope. This reorientation of post-65 Asian American literary history to the material conditions of science fictionality, rather than ethnic self-expression, has implications not only for understanding that history but also for generalized periodizations of contemporary US literature like the “genre turn,” which risk eliding the specificity of minority literary histories.
Repair of Lower Eyelid Cicatricial Entropion With Midface Lift, Spacer Graft, and Drill-Hole Canthoplasty
Authors: Alghoul Mohammed S , Bricker Jonathan T 
Published: November 2020

Abstract
Postoperative cicatricial lower lid retraction is a challenging surgical problem that often disfigures the shape of the eye and has functional consequences. Depending on the severity, more than one surgical procedure may be needed to achieve the desired lower lid shape and position given the recurrent nature of scarring. Concepts of scar release, establishing lower lid vertical height, soft tissue replacement, and midcheek support are discussed in this video.
Prediction of bio-sequence modifications and the associations with diseases
Authors: Ao Chunyan , Yu Liang , Zou Quan 
Published: November 2020

AbstractModifications of protein, RNA and DNA play an important role in many biological processes and are related to some diseases. Therefore, accurate identification and comprehensive understanding of protein, RNA and DNA modification sites can promote research on disease treatment and prevention. With the development of sequencing technology, the number of known sequences has continued to increase. In the past decade, many computational tools that can be used to predict protein, RNA and DNA modification sites have been developed. In this review, we comprehensively summarized the modification site predictors for three different biological sequences and the association with diseases. The relevant web server is accessible at http://lab.malab.cn/∼acy/PTM_data/ some sample data on protein, RNA and DNA modification can be downloaded from that website.
Deep feature extraction of single-cell transcriptomes by generative adversarial network
Authors: Bahrami Mojtaba , Maitra Malosree , Nagy Corina , Turecki Gustavo , Rabiee Hamid R , Li Yue 
Published: November 2020

Abstract

Motivation
Single-cell RNA-sequencing (scRNA-seq) offers the opportunity to dissect heterogeneous cellular compositions and interrogate the cell-type-specific gene expression patterns across diverse conditions. However, batch effects such as laboratory conditions and individual-variability hinder their usage in cross-condition designs.

Results
Here, we present a single-cell Generative Adversarial Network (scGAN) to simultaneously acquire patterns from raw data while minimizing the confounding effect driven by technical artifacts or other factors inherent to the data. Specifically, scGAN models the data likelihood of the raw scRNA-seq counts by projecting each cell onto a latent embedding. Meanwhile, scGAN attempts to minimize the correlation between the latent embeddings and the batch labels across all cells. We demonstrate scGAN on three public scRNA-seq datasets and show that our method confers superior performance over the state-of-the-art methods in forming clusters of known cell types and identifying known psychiatric genes that are associated with major depressive disorder.

Availabilityand implementation
The scGAN code and the information for the public scRNA-seq datasets are available at https://github.com/li-lab-mcgill/singlecell-deepfeature.

Supplementary information
Supplementary data are available at Bioinformatics online.
The New Contract Law in the Chinese Civil Code
Authors: Ling Bing 
Published: November 2020

Abstract
China’s new Civil Code, adopted in May 2020, includes a Book on contract law that brought about major developments in this important area of law. A full translation of the Book is presented, with an introductory essay reviewing some of the most significant issues that have emerged in the decade-long drafting of the new law. Various unresolved controversies foreshadow further debates and reform of the law in the future.
Genome-Wide Epigenetic Signatures of Adaptive Developmental Plasticity in the Andes
Authors: Childebayeva Ainash , Goodrich Jaclyn M , Leon-Velarde Fabiola , Rivera-Chira Maria , Kiyamu Melisa , Brutsaert Tom D , Dolinoy Dana C , Bigham Abigail W 
Published: November 2020

AbstractHigh-altitude adaptation is a classic example of natural selection operating on the human genome. Physiological and genetic adaptations have been documented in populations with a history of living at high altitude. However, the role of epigenetic gene regulation, including DNA methylation, in high-altitude adaptation is not well understood. We performed an epigenome-wide DNA methylation association study based on whole blood from 113 Peruvian Quechua with differential lifetime exposures to high altitude (&gt;2,500) and recruited based on a migrant study design. We identified two significant differentially methylated positions (DMPs) and 62 differentially methylated regions (DMRs) associated with high-altitude developmental and lifelong exposure statuses. DMPs and DMRs were found in genes associated with hypoxia-inducible factor pathway, red blood cell production, blood pressure, and others. DMPs and DMRs associated with fractional exhaled nitric oxide also were identified. We found a significant association between EPAS1 methylation and EPAS1 SNP genotypes, suggesting that local genetic variation influences patterns of methylation. Our findings demonstrate that DNA methylation is associated with early developmental and lifelong high-altitude exposures among Peruvian Quechua as well as altitude-adaptive phenotypes. Together these findings suggest that epigenetic mechanisms might be involved in adaptive developmental plasticity to high altitude. Moreover, we show that local genetic variation is associated with DNA methylation levels, suggesting that methylation associated SNPs could be a potential avenue for research on genetic adaptation to hypoxia in Andeans.
Sacrum imperium: Lombard Influence and the ‘Sacralization of the State’ in the Mid-twelfth Century Holy Roman Empire (1125–1167)
Authors: Sulovsky Vedran 
Published: November 2020

Abstract
Sacrum imperium (literally: holy empire) is a Latin phrase that entered the chancery of Holy Roman Emperor Frederick Barbarossa (1152–1190) in 1157. Sacrum imperium developed into the name of the Empire only much later, but scholars interpreted it as a programmatic phrase that Frederick and his chancellor, Rainald of Dassel, introduced as a part of their plan to ‘resacralize the state’ after its supposed desacralization by Pope Gregory VII (1073–1085) and the Empire’s defeat in the Investiture Controversy (1076–1122). In this article I show that sacrum imperium was introduced not by Frederick and Rainald but by a group of Italian courtiers who had developed a new political vocabulary based on that of Justinian’s Corpus iuris civilis and the contemporary Byzantine court language. I also demonstrate on the basis of Italian, Byzantine and papal sources that a desacralization of the state in 1122 never happened.
Connecting beamforming and kernel-based noise source inversion
Authors: Bowden Daniel C , Sager Korbinian , Fichtner Andreas , Chmiel Małgorzata 
Published: November 2020

SUMMARYBeamforming and backprojection methods offer a data-driven approach to image noise sources, but provide no opportunity to account for prior information or iterate through an inversion framework. In contrast, recent methods have been developed to locate ambient noise sources based on cross-correlations between stations and the construction of finite-frequency kernels, allowing for inversions over multiple iterations. These kernel-based approaches show great promise, both in mathematical rigour and in results, but are less physically intuitive and interpretable. Here we show that these apparently two different classes of methods, beamforming and kernel-based inversion, are achieving exactly the same result in certain circumstances. This paper begins with a description of a relatively simple beamforming or backprojection algorithm, and walks through a series of modifications or enhancements. By including a rigorously defined physical model for the distribution of noise sources and therefore synthetic correlation functions, we come to a framework resembling the kernel-based iterative approaches. Given the equivalence of these approaches, both communities can benefit from bridging the gap. For example, inversion frameworks can benefit from the numerous image enhancement tools developed by the beamforming community. Additionally, full-waveform inversion schemes that require a window selection for the comparisons of misfits can more effectively target particular sources through a windowing in a beamform slowness domain, or might directly use beamform heatmaps for the calculation of misfits. We discuss a number of such possibilities for the enhancement of both classes of methods, testing with synthetic models where possible.
A Boundary Estimate for Singular Sub-Critical Parabolic Equations
Authors: Gianazza Ugo , Liao Naian 
Published: November 2020

Abstract
We prove an estimate on the modulus of continuity at a boundary point of a cylindrical domain for local weak solutions to singular parabolic equations of $p$-Laplacian type, with $p$ in the sub-critical range $\big(1,\frac{2N}{N+1}\big]$. The estimate is given in terms of a Wiener-type integral, defined by a proper elliptic $p$-capacity.
Human Papillomavirus Prevalence and Integration Status in Tissue Samples of Bladder Cancer in the Chinese Population
Authors: Yan Yongji , Zhang Hongfeng , Jiang Chunfan , Ma Xin , Zhou Xueying , Tian Xun , Song Yuping , Chen Xu , Yu Liyao , Li Rui , Chen Hongwei , Wang Xin , Liu Ting , He Zhaohui , Li Hongzhao 
Published: November 2020

AbstractBackgroundHuman papillomavirus (HPV) infection is associated with multiple types of cancer, but the evidence has not yet been fully elucidated in bladder cancer.MethodsFrozen tissue samples collected from 146 patients aged 32 to 89 years with bladder cancer pathological diagnosis between 2015 and 2019 were analyzed. HPV genotyping and integration status determination were performed by capture-based next generation sequencing. Statistical analysis of HPV type distributions was performed according to stage, grade, sex, and age group of patients.ResultsMean (SD) age of the 146 patients was 66.64 ± 10.06 years and 83.56% were men. Overall HPV infection rate was 28.77% (37.50% in women and 27.05% in men), with 11.90% HPV integration events. Among them, 17.12% single and 11.65% coinfections were observed. HPV18 (24.66%) was the most prevalent genotype, followed by HPV33, 16, and 39. All HPV were European lineage (A). HPV16 was more prevalent in women (P = .04).ConclusionsHPV infection may contribute to the etiology both in men and women with bladder cancer. HPV18, followed by HPV33, 16, and 39 genotypes, potentially represent the predominant oncogenic risk types for bladder carcinogenesis.
Recent advances in generalized thermoelasticity theory and the modified models: a review
Authors: Shakeriaski Farshad , Ghodrat Maryam , Escobedo-Diaz Juan , Behnia Masud 
Published: November 2020

Abstract
A review of the recent studies on the generalized thermoelasticity theories and their associated modified models is presented. The aim is to outline an overview of the utilization and physical limitations of available relevant theories. By contrast to classical thermoelasticity theory, generalized thermoelasticity theories (second sound) can involve a hyperbolic-form transport correlation and are motivated by experiments illustrating more accurately of the wave-form heat transfer (second sound). Many researchers have formulated such theories on different fields and analyzed various problems, presenting characteristic properties of these theories. This paper expresses a self-included bibliographical review of previous documents in the area of the second sound. The general structure of this review contains theories, formulations, real limitations, and used solution techniques of the equations for different geometries and loadings. Given that the classical theory is feeble in simulating the temperature distribution, especially in the structures under a sudden thermal shock, this review may be a useful tool for researchers who work in sensitive industries such as steam turbines, micro-temperature sensors, and lithium battery manufacturing.
Cerebrum: Modelling the Mind through Psychedelic and Playful Environments
Authors: Lovell Jonathan 
Published: November 2020

Abstract
This article explores Cerebrum, a hybrid of a nightclub and a gallery, which for a brief moment in the late 1960s, used the combined force of media, performance and architecture to transform a Manhattan storefront into a series of virtual realities. Described as a ‘Psychedelic Playpen’, Cerebrum became—as its name suggests—an environmental model on the contemporary discourse on altered states of consciousness. It provided an eloquent expression of Timothy Leary’s advice on how to conduct a psychedelic trip, and Marshall McLuhan’s prediction that electronic media technologies would return humanity to the playful sensuality of preliterate societies. After being attended by Gene Youngblood and Alvin Toffler, Cerebrum was cited within their respective texts—Expanded Cinema and Future Shock—as evidence within their debate upon whether the pleasure generated by such environments would be used to challenge or consolidate structures of power. The purpose of this article is to elaborate on what constituted a typical night at Cerebrum and evaluate how it contributed to the post-war debate about the psycho-social implications of immersive multimedia environments.
US Court of Appeals for the Federal Circuit finds that administrative patent judges were unconstitutionally appointed in case now the subject of multiple appeals to the US Supreme Court
Authors: Macedo Charles R , Goldberg David P , Sturm Chandler 
Published: November 2020

Abstract
On 31 October 2020, a three-judge panel of the US Court of Appeals for the Federal Circuit (‘Federal Circuit’) issued a decision in Arthrex, Inc v Smith & Nephew, Inc finding that administrative patent judges of the Patent Trial and Appeal Board were appointed in violation of the Appointments Clause of the US Constitution and instituting measures to remedy the situation. On 23 March 2020, the Federal Circuit refused to the rehear the case sitting en banc. Since then, the panel decision has become the subject of multiple appeals to the US Supreme Court. We expect to learn in early autumn whether the US Supreme Court decides to grant certiorari with respect to any of the appeals and review this important decision.
Extraskeletal myxoid chondrosarcoma: a case report with adjuvant intraoperative treatment
Authors: Bacchetti Stefano , Pegolo Enrico , Adani Gianluigi , Macrì Antonio , Andreetta Claudia , Ermacora Paola , Girometti Rossano , Trovò Marco , Driul Lorenza , Di Loreto Carla , Pasqual Enricomaria 
Published: November 2020

Abstract
Extraskeletal myxoid chondrosarcoma is a rare form of malignant mesenchymal neoplasm mainly localized into the limbs, particularly in the thigh and popliteal fossa. It has been classified as a low-grade sarcoma so far, but it shows a tendency to relapse and metastasize. In the early stage of disease, surgery represents the only chance of cure. In case of diffuse metastatic disease, systemic chemotherapy with anthracyclines is the standard of care. In this paper, we present a case of a patient affected by this rare disease and the analysis of radiological, surgical and histopathological aspects.
Incidence of Hepatotoxicity in Iranian Patients With HIV on Antiretroviral Therapies and Its Correlation with Virologic Response to HIV Treatment
Authors: Hashempour Tayebeh , Moayedi Javad , Mousavi Zahra , Esmaeli Masoumeh , Asadzadeh Azizeh , Hasanshahi Zahra , Dehghani Behzad 
Published: November 2020

AbstractObjectiveTo investigate hepatotoxicity in Iranian patients with HIV to assess the association between virologic response to HIV treatment and serum alanine aminotransferase (ALT).MethodsThis study was conducted with 200 control patients, 75 patients with HIV naïve to antiretroviral therapy (ART), and 443 patients who received ARTs with virologic response (≤1000 copies/mL) or virologic treatment failure (&gt;1000 copies/mL). Serum ALT level and HIV viral load were determined in all patients.ResultsPatient ALT levels were significantly higher than those of control patients (45.1 ± 44.4 IU/L vs 23.8 ± 5.4 IU/L). Compared to patients who were ART-naïve, patients with ART experience had significantly higher ALT levels (38.2 ± 26.2 IU/L vs 46.3 ± 46.7 IU/L), and severe hepatotoxicity was only detected in those with ART experience (8 patients, 1.8%). Mean ALT had no significant difference between virologic response/failure groups. The ALT activity and HIV load had a negative correlation coefficient, but it was not significant.ConclusionPeriodic monitoring for the possibility of hepatotoxicity is highly recommended in all patients with HIV, especially in those receiving ART treatment.