bluuebunny/crossref_metadata_2025_split huggingface dataset:
A mathematical model for predicting indoor PM2.5 concentration under different ventilation methods in residential buildings
Authors: Xie Wei , Fan Yuesheng , Zhang Xin , Tian Guoji , Si Pengfei 
Published: February 2020

Experiments and theoretical analyses are conducted in a residential building in Changzhou to study indoor PM2.5 concentrations by establishing a combined parameter model. An alternative method for predicting the particle deposition rate and penetration coefficient is proposed, and its accuracy is tested and verified by experiments using time-dependent concentrations and air exchange rate measurements. The predicted PM2.5 penetration coefficient increased from 0.70 to 0.88 when the air exchange rates were varied from 0.2 h−1 to 0.5 h−1. In addition, outdoor sources of PM2.5 dominantly contributed approximately 90% to 98% to the indoor concentrations for both mechanically and naturally ventilated structures. Finally, a mathematical model for predicting the indoor concentration is presented using a mass balance equation, which estimates the parameter values in the building. The indoor PM2.5 concentrations ranged from 40 to 46 µg/m3 by using a fresh air system with 82% filtration efficiency, while those by using open windows for natural ventilation ranged from 105 to 118 µg/m3 when the outdoor PM2.5 concentration ranged from 115 to 137 µg/m3. The results of this study can be used to estimate the indoor particle level. Practical application: By applying the ventilation criteria for acceptable indoor air quality in ASHRAE Standard 62.1, the indoor PM2.5 monitoring results show serious pollution in dwellings in 2018. More dwellings are expected to maintain a clean indoor environment in the future. Thus, it is crucial to consider the indoor PM2.5 pollution risk in the building design to prevent the possible consequences of unsafe high indoor concentrations. The use of this prediction model, as discussed in this article, will provide further information on the influence of the particle deposition rate ( K) and penetration coefficient ( P) on indoor PM2.5 concentrations.
The Economic Burden of Vertigo: Results From the Hospitalized and Outpatients
Authors: Özdemir Şule , Özdemir Doğukan , Terzi Özlem , Mehel Dursun Mehmet , Özgür Abdulkadir 
Published: February 2020

Objective: Vertigo and dizziness are the common presenting concerns in emergency departments and outpatient clinics, accounts for approximately 15% to 20% of adults annually. We aimed to evaluate economic burden of vertigo on health-care system and work productivity in association between clinic characteristics of in- or outpatients. Methods: A total number of 2289 patients diagnosed with peripheric (noncentral) vertigo were evaluated retrospectively. The direct medical costs associated with vertigo classified as medication, consumable, imaging, and laboratory. In addition, the indirect costs were associated with lost working days. The overall economic impact of vertigo assessed via total expenditure for diagnosis and treatment. Results: The mean duration of hospitalization was 5.6 ± 4.3 days and working day lost was 9.47 ± 3.90 days. The overall impact on work productivity of disease was 15.35 ± 6.11 days. The overall mean direct cost including all expenditure items associated with vertigo care was $250.25 ± $1479.62 per patient. The overall cost associated with vertigo was found to be statistically increased in the male, aged ≥65 years, widow or divorced, and hospitalized patients. Conclusions: Our findings clearly indicate that a vertigo–dizziness management program based on patients’ risk factors may achieve to reduce hospitalizations and cost of hospital care as well.
Radiology Interest Groups: A Recipe for Success
Authors: Dobson Jessica L. , Fenwick Andrew , Linehan Victoria , Hartery Angus 
Published: February 2020

Objectives: Radiology Interest Groups (RIGs) are valuable for medical students and the radiology profession. The purpose of this study is to identify key components of a successful RIG and to discuss how to optimize available resources to increase student engagement in radiology. Methods: Anonymous feedback forms (n = 478) completed by preclinical medical students attending 20 RIG events between September 2016 and May 2019 were analyzed. A five-point Likert-type scale was used to determine event effectiveness, and important themes reflecting student perspectives were identified using thematic analysis of freeform comments. Results: Based on Likert feedback, 75% to 78% of students had a positive experience of RIG events and believed sessions were relevant to their studies. 31% to 42% of students believed these events increased their interest or insight into radiology and influenced their career choice. Four representative themes were identified by qualitative analysis of written feedback: engagement, professional development, mentorship, and suggestions for improvement. These themes provided insight into student perspectives of our RIG, and, along with experience from the RIG organizers, the authors present elements perceived to have contributed to these positive results. Conclusion: Thematic analysis of feedback reveals that students consider interactive events, contribution to professional development, and the opportunity for mentorship valuable elements of a RIG. From the perspective of the organizing committee, we embody these aspects through careful planning, innovative events, and consistent debriefing. In this way, our RIG promotes the future of the radiology profession and serves as a practical model for other similar organizations.
Effects of Deep Learning Reconstruction Technique in High-Resolution Non-contrast Magnetic Resonance Coronary Angiography at a 3-Tesla Machine
Authors: Yokota Yasuhiro , Takeda Chika , Kidoh Masafumi , Oda Seitaro , Aoki Ryo , Ito Kenichi , Morita Kosuke , Haraoka Kentaro , Yamashita Yuichi , Iizuka Hitoshi , Kato Shingo , Tsujita Kenichi , Ikeda Osamu , Yamashita Yasuyuki , Utsunomiya Daisuke 
Published: February 2020

Purpose: To evaluate the effects of deep learning reconstruction (DLR) in qualitative and quantitative image quality of non-contrast magnetic resonance coronary angiography (MRCA). Methods: Ten healthy volunteers underwent conventional MRCA (C-MRCA) and high-resolution (HR) MRCA on a 3T magnetic resonance imaging with a voxel size of 1.8 × 1.1 × 1.7 mm3 and 1.8 × 0.6 × 1.0 mm3, respectively, for C-MRCA and HR-MRCA. High-resolution magnetic resonance coronary angiography was also reconstructed with the DLR technique (DLR-HR-MRCA). We compared the contrast-to-noise ratio (CNR) and visual evaluation scores for vessel sharpness and traceability of proximal and distal coronary vessels on a 4-point scale among 3 image series. Results: The vascular CNR value on the C-MRCA and the DLR-HR-MRCA was significantly higher than that on the HR-MRCA in the proximal and distal coronary arteries (13.9 ± 6.4, 11.3 ± 4.4, and 7.8 ± 2.6 for C-MRCA, DLR-HR-MRCA, and HR-MRCA, P < .05, respectively). Mean visual evaluation scores for the vessel sharpness and traceability of proximal and distal coronary vessels were significantly higher on the HR-DLR-MRCA than the C-MRCA ( P < .05, respectively). Conclusion: Deep learning reconstruction significantly improved the CNR of coronary arteries on HR-MRCA, resulting in both higher visual image quality and better vessel traceability compared with C-MRCA.
Impact of a Student Pharmacist Pilot Focused on the Transitions of Care Process From Emergency Department Visits to Family Medicine Follow-Up in a Rural Patient Setting
Authors: DeRemer Christina E. , Lyons Shannon R. , Harman Emily J. , Quinn Karina , Konopack Jason 
Published: February 2020

Introduction: Few would argue that emergency department utilization volumes do not tax the health system. Currently, there is not a process defined by Centers for Medicare and Medicaid Services for transitioning this patient population back to their primary physicians following emergency department visits. Resource limitations in a rural family medicine setting create barriers to dedicate focus on this important transitional care management from urgent care visits to primary care office. Objective: To describe a novel pilot process for transitional care management from the emergency department utilizing pharmacy student extenders to overcome resource limitation at a rural family medicine clinic and establish follow-up primary physician contact. Methods: From a master list provided, student pharmacists proactively telephoned patients and reviewed medication changes while assisting with scheduling follow-up appointments at the patient’s primary physician clinic. Results: The result of these efforts increased the communication with patients and resulted in a 26% (10/38) increase in follow-up appointments scheduled with a total increase of an additional 7 patients adhering to follow-up transitional appointment. Conclusion: This approach utilizing student extenders is a feasible and sustainable process that can increase patient contact when resources are limited, while serving as an educational tool for next generation providers.
The Effectiveness of Palate Re-Repair for Treating Velopharyngeal Insufficiency: A Systematic Review and Meta-Analysis
Authors: Kurnik Nicole M. , Weidler Erica M. , Lien Kari M. , Cordero Kelly N. , Williams Jessica L. , Temkit M’hamed , Beals Stephen P. , Singh Davinder J. , Sitzman Thomas J. 
Published: February 2020

Background: Palate re-repair has been proposed as an effective treatment for velopharyngeal insufficiency (VPI) with a low risk of obstructive sleep apnea (OSA). The authors conducted a systematic review and meta-analysis to determine the proportion of patients achieving normal speech resonance following palate re-repair for VPI, the proportion developing OSA, and the criteria for patient selection that are associated with increased effectiveness. Methods: PubMed, Embase, and Scopus were searched from inception through April 2018 for English language articles evaluating palate re-repair for the treatment of VPI in patients with a repaired cleft palate. Inclusion criteria included reporting of hypernasality, nasal air emission, nasometry, additional VPI surgery, and/or OSA outcomes. Meta-analysis was conducted using random effects models. Risk of bias was assessed regarding criteria for patient selection, blinding of outcome assessors, and validity of speech assessment scale. Results: Eighteen studies met inclusion criteria. The incidence of achieving no consistent hypernasality follow palate re-repair was 61% (95% confidence interval [CI]: 44%-75%). The incidence of additional surgery for persistent VPI symptoms was 21% (95% CI: 12%-33%). The incidence of OSA was 28% (95% CI: 13%-49%). Criteria for selecting patients to undergo re-repair varied, with anterior/sagittal position of palatal muscles (33%) and small velopharyngeal gap (22%) being the most common. No specific patient selection criteria led to superior speech outcomes ( P = .6572). Conclusions: Palate re-repair achieves normal speech resonance in many but not all patients with VPI. Further research is needed to identify the specific examination and imaging findings that predict successful correction of VPI with re-repair.
The impact of placental pathology discordance in multiple gestation pregnancies on bronchopulmonary dysplasia‐associated pulmonary hypertension
Authors: Franklin Andrew , Yallapragada Sushmita , Birkett Robert , Grobman William , Ernst Linda M. , Mestan Karen 
Published: February 2020

Bronchopulmonary dysplasia‐associated pulmonary hypertension (BPD‐PH) may either be concordant or discordant between multiple gestation births. Abnormal placental development, particularly maternal vascular malperfusion, may account for discordance in BPD‐PH through fetal programming mechanisms. Maternal vascular malperfusion is a placental histologic lesion associated with intrauterine growth restriction and BPD‐PH. We conducted a retrospective longitudinal cohort study of infants born <29 weeks gestation with available placental histology at Prentice Women's Hospital in Chicago from 2005–2012. The primary outcome was discordant BPD‐PH associated with placental maternal vascular malperfusion. We secondarily assessed whether the risk of BPD‐PH and placental lesions was different among infants of multiple (compared to singleton) gestations. The cohort consisted of 135 multiple gestation infants and 355 singletons. In a separate cohort of 39 singletons and 35 multiples, associations between 12 cytokines and angiogenic growth factors in cord blood plasma for biomarker discordance, maternal vascular malperfusion, and bronchopulmonary dysplasia were explored. Among multiples, discordant maternal vascular malperfusion was not associated with BPD‐PH (OR = 1.9 (0.52, 6.9); p = 0.33) in infants exposed to placental maternal vascular malperfusion. However, singleton infants were more likely to develop BPD‐PH (compared to multiples) after adjusting for mode of delivery, chorioamnionitis, chronic hypertension, placental abruption, small‐for‐gestational age birth weight, and gestational age (aOR = 2.7 (1.2, 5.8); p = 0.038). Singletons were more likely to be small‐for‐gestational age (11% vs 4%, p = 0.025) and have placental lesions compared to their multiple‐gestation counterparts (96% vs 81%, p < 0.001), principally severe maternal vascular malperfusion (17% vs 4%, p < 0.001) and chronic inflammation (32% vs 11%, p < 0.001). Increased risk of BPD‐PH in singleton pregnancies <29 weeks gestation compared to multiples may be related to increased frequency of these histologic lesions. Placental pathology in singleton and multiple gestation pregnancies may serve as an early biomarker to predict BPD‐PH.
Implementing a Competency-Based Approach to Anatomy Teaching: Beginning With the End in Mind
Authors: Jalali Alireza , Jeong Dahn , Sutherland Stephanie 
Published: February 2020

Background: The shift in the medical education system from a time-based to a competency-based model has encouraged its adoption and application in competency-based education in anatomy classrooms, such as team-based learning models and flipped classroom models. This pilot study aimed to build on previous work of the linkages between anatomy-based learning (a flipped classroom model inspired by a modified team-based learning) and student learning and engagement, and further to assess the linkage between anatomy-based learning and academic performance. Methods: A sequential mixed-methods design was employed to first gather and analyse quantitative data, including confidential student first semester scores in anatomy: gender, stream, anatomy-based learning, and final anatomy overall mark. The quantitative phase was followed by a qualitative phase in which a series of 8 anatomy laboratories were observed (4 anatomy-based learning and 4 traditional). Thematic analysis was performed on the observation data. Results: Aggregate anatomy-based learning and traditional stream tests, and final unit scores were compared. The anatomy-based learning and final unit scores showed little difference between students in the anatomy-based learning and students in the traditional stream. Students using anatomy-based learning had an aggregate score of 1.15 and final aggregate mark of 72, whereas students in the traditional section had an aggregate score of 1.19 and final mark of 79. Qualitative phase was undertaken to try to assess the linkages between anatomy-based learning and student learning. Observations showed that students in the anatomy-based learning section spent more time on task as compared with their peers in the traditional stream. The anatomy-based learning students also seemed to practice more self-directed learning and employed more multimodal learning strategies than the traditional section stream. Discussion/conclusions: Although the quantitative results of this study showed no significant difference in mean scores between anatomy-based learning and traditional designs, it was possible to observe the potential of flipped classroom model in engaging students in individual preparation, in team-based learning, and in consensus-based learning approaches.
Electric-Controlled Valley Pseudomagnetoresistance in Graphene with Y-Shaped Kekulé Lattice Distortion
Authors: Wu Qing-Ping , Chang Lu-Lu , Li Yu-Zeng , Liu Zheng-Fang , Xiao Xian-Bo 
Published: February 2020

AbstractWe propose a new method for regulating valley pseudomagnetoresistance in ballistic graphene-based valley field-effect transistors by taking into account the Y-shaped Kekulé lattice distortion and electric barrier. The device involves valley injection and valley detection by ferromagnetic-strain source and drain. The valley manipulation in the channel is achieved via the Y-shaped Kekulé lattice distortion and electric barrier. The central mechanism of these devices lies on Y-shaped Kekulé lattice distortion in graphene can induce a valley precession, thus controlling the valley orientation of channel electrons and hence the current collected at the drain. We found that the tuning external bias voltage makes the valley pseudomagnetoresistance oscillate between positive and negative values and colossal tunneling valley pseudomagnetoresistance of over 30,000% can be achieved. Our results suggest that the synergy of valleytronics and digital logics may provide new paradigms for valleytronic-based information processing and reversible computing.
Mechanisms and pathways to impact in public health research: a preliminary analysis of research funded by the National Institute for Health Research (NIHR)
Authors: Boulding Harriet , Kamenetzky Adam , Ghiga Ioana , Ioppolo Becky , Herrera Facundo , Parks Sarah , Manville Catriona , Guthrie Susan , Hinrichs-Krapels Saba 
Published: February 2020

AbstractBackgroundThe mechanisms and pathways to impacts from public health research in the UK have not been widely studied. Through the lens of one funder (NIHR), our aims are to map the diversity of public health research, in terms of funding mechanisms, disciplinary contributions, and public health impacts, identify examples of impacts, and pathways to impact that existing reporting mechanisms may not otherwise have captured, and provide illustrations of how public health researchers perceive the generation of non-academic impact from their work.MethodsA total of 1386 projects were identified as ‘public health research’ by the NIHR and listed in the NIHR Public Health Overview database (2000–2016). From these, a subset of 857 projects were matched as potentially having begun reporting impacts via an external data-gathering platform (Researchfish). Data on the 857 projects were analyzed quantitatively, and nine projects were selected to investigate further through semi-structured interviews with principal investigators. Two workshops took place to validate emerging and final findings and facilitate analysis.ResultsIn addition to the NIHR School for Public Health Research and the NIHR Public Health Research Programme, 89% of projects contained in the NIHR Public Health Overview portfolio as ‘public health research’ are funded via other NIHR research programmes, suggesting significant diversity in disciplines contributing to public health research and outcomes. The pathways to impact observed in our in-depth case studies include contributing to debates on what constitutes appropriate evidence for national policy change, acknowledging local ‘unintended’ impacts, building trusted relationships with stakeholders across health and non-health sectors and actors, collaborating with local authorities, and using non-academic dissemination channels.ConclusionsPublic health as a discipline contributes substantially to impact beyond academia. To support the diversity of these impacts, we need to recognise localized smaller-scale impacts, and the difference in types of evidence required for community and local authority-based impacts. This will also require building capacity and resources to enable impact to take place from public health research. Finally, support is required for engagement with local authorities and working with non-health sectors that contribute to health outcomes.
Discharge outcomes among elderly patients undergoing emergency abdominal surgery: registry study of discharge data from Irish public hospitals
Authors: McCann Aisling , Sorensen Jan , Nally Deirdre , Kavanagh Dara , McNamara Deborah A. 
Published: February 2020

Abstract
Background
Intra-abdominal emergency surgery is associated with high mortality risk and long length of hospital stay. The objective of this study was to explore variations in surgery rates, the relationship between admission source and discharge destination, and whether the postoperative length of stay was related to nursing home capacity in Irish counties.

Methods
Data on emergency hospital episodes for 2014–18 for patients aged over 65 years with a primary abdominal procedure code were obtained from the National Quality Assurance Improvement System. Data on population and nursing home capacity were obtained from the Central Statistics Office and the Health Information and Quality Authority. Episode rates per 100,000 were estimated for sex and age groups and compared between 26 Irish counties. The association between admission source and discharge destination was explored in terms episode numbers, length of stay and mortality. A negative binomial regression model estimated casemix adjusted excess post-operative length of stay. The correlation between excess post-operative length of stay and nursing home capacity was explored by linear regression.

Results
Overall, 4951 hospital episodes were included. The annual surgery rate ranged from 100 episodes per 100,000 65–69 years old to 250 per 100,000 85–89 year old men. 90% of the episodes were admitted from patients’ home. Four in five of these patients returned to their home while 12.7% died at hospital. The proportion of episodes where patients returned to their home reduced to two in five for those aged 85–89 years. The post-operative length of stay was 13.6 days longer (p < 0.01) for episodes admitted from home and discharged to nursing home in comparison with episodes discharged home. A negative association (p = 0.08) was found between excess post-operative length of stay and county-level nursing home capacity.

Conclusions
This study provides relevant information to support informed consent to surgery for patients and clinicians and to improve the provision of care to older patients presenting with intra-abdominal emergencies.