bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trends of genetic parameters and stand volume productivity of selected clones of Eucalyptus pellita observed in clonal trials in Wonogiri, Central Java
Authors: Kartikaningtyas D , Nirsatmanto A , Sunarti S , Setyaji T , Handayani B R , Surip  
Published: July 2020

Abstract
Breeding program of Eucalyptus pellita has proceeded into advanced generationswith clonal development as best way to deliver greater genetic gain. Clonal test is a prerequisite for selecting and verifying the clones productivity before deployment. Following the breeding strategy, clonal trials of E. pellita were established in Wonogiri, CentralJava. The purposes of this study are to observe trends of genetic parameters and stand volume productivity of clones tested in clonal trials of E. pellita. The trials were laid out in two experimental designs: 1) nine clones, 16 replications, single tree-plot, spacing 3 x 2m;2) 4 clones, 2-4 replications, 16 squares tree-plot, spacing 3 x 2m. Each trial also contains control (i.eseedling material). Measurements were conducted five times from six monthsto 46 months age. Results showed that trends of growth increased along the measurements with nine tested clones performed better than control seedlings. The growths were significantly different among clones along the ages with clone repeatibility ranging from 0.49 to 0.98.Three selected clones namely clone 1,2 and 3on the basis of height growth and multiplication rates showed higher stand volume productivity compared to control and consistently increased on average of0.37 m3/ha at 6 months to 73.93 m3/ha at 46 months age.
Evaluation of five seeds of medicinal plants in the nursery level
Authors: Hakim L 
Published: July 2020

Abstract
Five plants i.e.Kemuning (Murrayapaniculata (L.) Jack), Temurui (Murrayakoenigii (L.) Spreng), Kuntobimo (Kigeliaafricana (Lam.) Benth. Syn. K. pinnata (Jacq.) DC.),Sala (CouroupitaguianensisAubl), and Salam (Syzygiumpolyanthum (Wight) Walp.) are regarded as types of plants that have the potential to be developed as raw materials for herbal medicine. Those five plants were planted in thespecies trial as well as ex-situ conservation plots in the Grand Forest Park Bunder, Gunungkidul at the end of 2018. This study aimsto find out more about research status of these plant types by literature review method, e.g. from books, proceedings, both print and online journals, and conducting seed evaluation in the Yogyakarta Center for Forest Biotechnology and Tree Improvement. Seed evaluation method in the nursery was conducted by measuring diameter, height and sturdiness of as many as 36 seedlings for each plant. The seed evaluation in the nursery showed the average diameter of 4.93 mm, theaverage height of 31.66 cm, and the average seedling sturdiness of 6.63. The evaluation results also show that the best seeds ready for field test planting in order are Sala, Salam, and Kemuning. As for Temurui and Kuntobimo seedlings, due to their limited height, an intensive maintenance is needed, especially fertilization, so that at the end of the year theywould also beready for field planting.
Vegetation Structure and Potential of Blue Carbon based on Hydromorphic Degraded Mangrove in the Northern Manokwari, West Papua
Authors: Hendri  , Hadiyan Y , Rumbruren YP , Moeljono S , Maturbongs R. 
Published: July 2020

Abstract
The mangrove forest in northern West Papua Province has important roles in both economic and ecological interests. This forest is facing various pressures so it is now degraded. The objective of this study was to ascertain the vegetation structure and potential for the blue carbon reserves. The bio-physical characteristic data were collected by establishing sampling plots at 2 locations representing coastal and estuarine mangrove forest. The results showed that the species diversity index in Saubeba Bay (estuarine mangrove) was low (H’= 1.26), while, the species diversity index in Saukori Bay (coastal mangrove) was very low (H’= 0.66). In Saubeba Bay,Bruguiera cyclindrica and Avicenialanatahad the largest IVI, namely 87.47% and 80.55% respectively, while in Bay SaukoriAegiceras floridumhad the highest IVI (139.01%). The total carbon stocks of AGB and BGB of mangrove forest in Saubeba Bay were 224,77 MgC/ha and 77,57 MgC/ha respectively, while those in Saukori Baywere 174,90 MgC/ha and 59,98 MgC/ha, respectively.
Using Predicted Atherosclerotic Cardiovascular Disease Risk for Discrimination of Awake or Nocturnal Hypertension
Authors: Sakhuja Swati , Booth John N , Anstey David E , Jaeger Byron C , Lewis Cora E , Lloyd-Jones Donald M , Schwartz Joseph E , Shimbo Daichi , Shikany James M , Sims Mario , Muntner Paul 
Published: July 2020

Abstract

BACKGROUND
Several atherosclerotic cardiovascular disease (ASCVD) risk factors are associated with awake and nocturnal hypertension.

METHODS
We assessed the association between a composite ASCVD risk score and awake or nocturnal hypertension using data from participants aged 40–79 years who completed ambulatory blood pressure monitoring at the Year 30 Coronary Artery Risk Development in Young Adults study exam in 2015–2016 (n = 716) and the baseline Jackson Heart Study exam in 2000–2004 (n = 770). Ten-year predicted ASCVD risk was calculated using the Pooled Cohort risk equations. Awake hypertension was defined as mean awake systolic blood pressure (SBP) ≥135 mm Hg or diastolic blood pressure (DBP) ≥85 mm Hg and nocturnal hypertension was defined as mean asleep SBP ≥120 mm Hg or DBP ≥70 mm Hg.

RESULTS
Among participants with a 10-year predicted ASCVD risk &lt;5%, 5% to &lt;7.5%, 7.5% to &lt;10%, and ≥10%, the prevalence of awake or nocturnal hypertension as a composite outcome was 29.5%, 47.8%, 62.2%, and 69.7%, respectively. After multivariable adjustment, higher ASCVD risk was associated with higher prevalence ratios for awake or nocturnal hypertension among participants with clinic-measured SBP/DBP &lt;130/85 mm Hg but not ≥130/85 mm Hg. The C-statistic for discriminating between participants with vs. without awake or nocturnal hypertension was 0.012 (95% confidence interval 0.003, 0.016) higher when comparing a model with ASCVD risk and clinic-measured blood pressure (BP) together vs. clinic-measured BP without ASCVD risk.

CONCLUSIONS
Using 10-year predicted ASCVD risk in conjunction with clinic BP improves discrimination between individuals with and without awake or nocturnal hypertension.
Presymptomatic Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 Among Residents and Staff at a Skilled Nursing Facility: Results of Real-time Polymerase Chain Reaction and Serologic Testing
Authors: Goldberg Scott A , Lennerz Jochen , Klompas Michael , Mark Eden , Pierce Virginia M , Thompson Ryan W , Pu Charles T , Ritterhouse Lauren L , Dighe Anand , Rosenberg Eric S , Grabowski David C 
Published: July 2020

Abstract
High rates of asymptomatic coronavirus disease 2019 infection suggest benefits to routine testing in congregate care settings. Screening was undertaken in a single nursing facility without a known case of coronavirus disease 2019, demonstrating an 85% prevalence among residents and 37% among staff. Serology was not helpful in identifying infections.
Shallow structure of Los Humeros (LH) caldera and geothermal reservoir from magnetotellurics and potential field data
Authors: Corbo-Camargo Fernando , Arzate Jorge , Fregoso Emilia , Norini Gianluca , Carrasco-Núñez Gerardo , Yutsis Vsevolod , Herrera Juan , Hernández Javier 
Published: July 2020

SUMMARYThis study focuses in the analysis of the internal structure of the upper 3 km of Los Humeros (LH) caldera and the relation of electrical and hydrothermal anomalies. For this purpose, we measured, processed and interpreted 78 broad-band magnetotelluric (MT) soundings. We performed a 3-D inversion of the data set (ModEM) using all MT soundings, although only half of the available frequencies per sounding due to limited computed power. We also carried out the 2-D inversions (NLCG) of the invariant determinant along two orthogonal profiles (EW and NS) crossing the caldera structure; their comparison yields similar resistivity and structural models results. The resistivity modelling is complemented with the results of a joint 3-D inversion of an accurate gravity database of 720 stations, and total field aeromagnetic data (SGM) from the caldera crater. The combined results provide novel details about the structure of the shallow geothermal reservoir of the resurgence caldera complex hosting the active hydrothermal system. Density and resistivity models show the existence of a composed crater basin structure separated by an EW high-density structure; the northern basin is associated to the LH crater, whereas the southern basin associates to the emergent Los Potreros (LP) caldera basin. The magnetization model indicates that there is a common source for the magnetic volcanic products observed at the caldera surface, and that the LP fault is the more magnetized fault of the geothermal system. The propylic zoning under the geothermal field, which according to the MT model results has resistivities above ∼100 Ω-m, was extrapolated using this and additional criteria to obtain the distribution of other hypothetical propylitic zones of hydrothermal potential.
Periostin Is Expressed by Pericytes and Is Crucial for Angiogenesis in Glioma
Authors: Huizer Karin , Zhu Changbin , Chirifi Ihsan , Krist Bart , Zorgman Denise , van der Weiden Marcel , van den Bosch Thierry P P , Dumas Jasper , Cheng Caroline , Kros Johan M , Mustafa Dana A 
Published: July 2020

Abstract
The expression of the matricellular protein periostin has been associated with glioma progression. In previous work we found an association of periostin with glioma angiogenesis. Here, we screen gliomas for POSTN expression and identify the cells that express periostin in human gliomas. In addition, we study the role of periostin in an in vitro model for angiogenesis. The expression of periostin was investigated by RT-PCR and by immunohistochemistry. In addition, we used double labeling and in situ RNA techniques to identify the expressing cells. To investigate the function of periostin, we silenced POSTN in a 3D in vitro angiogenesis model. Periostin expression was elevated in pilocytic astrocytoma and glioblastoma, but not in grade II/III astrocytomas and oligodendrogliomas. The expression of periostin colocalized with PDGFRβ+ cells, but not with OLIG2+/SOX2+ glioma stem cells. Silencing of periostin in pericytes in coculture experiments resulted in attenuation of the numbers and the length of the vessels formation and in a decrease in endothelial junction formation. We conclude that pericytes are the main source of periostin in human gliomas and that periostin plays an essential role in the growth and branching of blood vessels. Therefore, periostin should be explored as a novel target for developing anti-angiogenic therapy for glioma.
Physiological dormancy broken by endozoochory: Austral parakeets (Enicognathus ferrugineus) as legitimate dispersers of calafate (Berberis microphylla) in the Patagonian Andes
Authors: Bravo Carolina , Chamorro Daniel , Hiraldo Fernando , Speziale Karina , Lambertucci Sergio A , Tella José L , Blanco Guillermo 
Published: July 2020

Abstract

Aims
Seed dispersal by endozoochory is an important process in plant regeneration and the establishment of new populations. Seeds with dormancy may especially benefit after disperser gut passage. However, the ways in which gut passage affect the germination of plant species with physiological dormancy remain unclear. Here, we experimentally assessed the mutualistic interaction between the Austral parakeet (Enicognathus ferrugineus) as a disperser of calafate (Berberis microphylla), a thorny bush inhabiting the understory of the Austral temperate forests of South America with seeds that are characterized by deep physiological dormancy.

Methods
Germination success and viability of calafate seeds obtained from faeces and from intact fruits were tested under four treatments: (i) digested seeds, (ii) digested seeds with faecal extract, (iii) intact seeds from fruit and (iv) intact seeds from fruit with pulp.

Important Findings
About 65% of the Austral parakeet droppings contained calafate seeds. Viability of seeds did not differ between treatments. However, germination was significantly higher in digested seeds than in intact seeds from fruits, while no difference was found between faecal and pulp extracts. Neither faecal matter nor fruit pulp provided seeds with any ecological advantages derived from enhancing germinability, but did confer some disadvantage in germination time. Faecal matter is expected to be completely lacking around seeds after several months under snow before germinating in the following spring, given intense washing due to persistent rain and the spring thaw in the Patagonian Andes. The higher germinability along with faster germination of digested seeds supports the hypothesis of a legitimate mutualistic interaction between Austral parakeets and calafate. We hypothesized that the passage through the disperser digestive tract might break physiological dormancy as differences in germinability between ingested and non-ingested seeds. Our results highlight the relevant role of endozoochory in plant species with physiological dormancy living in highly seasonal environments.
Physiological and biomass partitioning shifts to water stress under distinct soil types in Populus deltoides saplings
Authors: Yang Senlin , Shi Jian , Chen Lianghua , Zhang Jian , Zhang Danju , Xu Zhenfeng , Xiao Jiujin , Zhu Peng , Liu Yang , Lin Tiantian , Zhang Li , Yang Hanbo , Zhong Yu 
Published: July 2020

Abstract

Aims
Although soil environments exist extensive heterogeneity for many plants with a wide range of distribution, researches about effects of soil conditions on plants’ tolerance and adaptation are particularly inadequate. In our study, the aims are to reveal physiological strategies of Populus deltoides against drought stress under different soil conditions and to select the most suitable soil type for P. deltoides plantation.

Methods
Under controlled conditions, we used P. deltoides as a model species to detect differences in gas exchange rate, antioxidative capacity, nitrogen metabolism and biomass accumulation and partitioning in response to drought stress under three mineral soil types with distinct physicochemical characters, i.e. red soil (RS), yellow soil (YS) and yellow-brown soil (BS).

Important Findings
Exposure to 25% of field water holding capacity in soil for 3 months had significantly decreased biomass of all organs, photosynthetic rate, enzyme activities related to N assimilation, but increased H2O2, malondialdehyde and content of both NO3− and NH4+, when P. deltoides was planted in both RS and YS. In contrast, under BS, there are slightly negative effects exerted by water deficit on total biomass, gas exchange rate, activities of enzymes related to nitrogen metabolism and membrane damage caused by reactive oxygen species, which can be associated with a consistent increase in superoxide dismutase, peroxidase and catalase, and a higher ratio of root mass to shoot mass. It is concluded that, such higher capacity in tolerance and adaptation against drought stress under BS relative to both RS and YS could be accounted for more sufficient nutrient provision in soil parental materials and better soil aeration conditions which play a vital role in plant acclimation to water shortage. Our study also revealed that, distribution areas of BS might be preferable for cultivation of P. deltoides, when compared with those of RS and YS.
Early induction and increased risk of precursor B-cell neoplasms after exposure of infant or young-adult mice to ionizing radiation
Authors: Tachibana Hirotaka , Morioka Takamitsu , Daino Kazuhiro , Shang Yi , Ogawa Mari , Fujita Misuzu , Matsuura Akira , Nogawa Hiroyuki , Shimada Yoshiya , Kakinuma Shizuko 
Published: July 2020

Abstract
Epidemiological studies of atomic-bomb survivors have revealed an increased risk of lymphoid neoplasm (i.e. acute lymphoblastic leukemia) associated with radiation exposure. In particular, children are more susceptible to radiation-induced precursor lymphoid neoplasm than adults. Although ~75% of human lymphoid tumors are B-cell neoplasms, the carcinogenic risk associated with each stage of differentiation of B-cells after radiation exposure is poorly understood. Therefore, we irradiated mice at infancy or in young adulthood to investigate the effect of age at exposure on the risk of developing B-cell neoplasms. Histopathology was used to confirm the presence of lymphoid neoplasms, and the population of B-cell neoplasms was classified into the precursor B-cell (pro-B and pre-B cell) type and mature B-cell type, according to immunophenotype. The data revealed that precursor B-cell neoplasms were induced soon after radiation exposure in infancy or young adulthood, resulting in a greater risk of developing the neoplasms. This was particularly the case for the pro-B cell type after young adult exposure. Our findings suggest that exposure to radiation at young age increases the risk of developing precursor B-cell neoplasms in humans.
The inner gas mass–temperature profile in the core of nearby galaxy clusters
Authors: Liu Haonan , Fabian Andrew C , Pinto Ciro 
Published: July 2020

ABSTRACT
We present a mass–temperature profile of gas within the central 10 kpc of a small sample of cool core clusters. The mass of the hottest gas phases, at 1.5 and 0.7 keV, is determined from X-ray spectra from the XMM Reflection Grating Spectrometers. The masses of the partially ionized atomic and the molecular phases are obtained from published H α and CO measurements. We find that the mass of gas at 0.7 keV in a cluster is remarkably similar to that of the molecular gas. Assuming pressure equilibrium between the phases, this means that they occupy volumes differing by 105. The molecular gas is located within the H α nebula which is often filamentary and coincides radially and in position angle with the soft X-ray emitting gas.
Regulation of MALAT1 triple helix stability and in vitro degradation by diphenylfurans
Authors: Donlic Anita , Zafferani Martina , Padroni Giacomo , Puri Malavika , Hargrove Amanda E 
Published: July 2020

AbstractSmall molecule-based modulation of a triple helix in the long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been proposed as an attractive avenue for cancer treatment and a model system for understanding small molecule:RNA recognition. To elucidate fundamental recognition principles and structure–function relationships, we designed and synthesized nine novel analogs of a diphenylfuran-based small molecule DPFp8, a previously identified lead binder of MALAT1. We investigated the role of recognition modalities in binding and in silico studies along with the relationship between affinity, stability and in vitro enzymatic degradation of the triple helix. Specifically, molecular docking studies identified patterns driving affinity and selectivity, including limited ligand flexibility, as observed by ligand preorganization and 3D shape complementarity for the binding pocket. The use of differential scanning fluorimetry allowed rapid evaluation of ligand-induced thermal stabilization of the triple helix, which correlated with decreased in vitro degradation of this structure by the RNase R exonuclease. The magnitude of stabilization was related to binding mode and selectivity between the triple helix and its precursor stem loop structure. Together, this work demonstrates the value of scaffold-based libraries in revealing recognition principles and of raising broadly applicable strategies, including functional assays, for small molecule–RNA targeting.
Mental Health for Individuals with Pansexual and Queer Identities
Authors: Galupo M. Paz 
Published: July 2020

AbstractThere is a growing need to articulate a framework for exploring mental health disparities among individuals with pansexual and queer identities. This chapter provides an overview of the methodological challenges for researching plurisexuality in general, and pansexual and queer identities in particular. Challenges include the conceptualization of sexuality on a continuum, assumptions of alignment normativity, and the use of multiple labels. The author discusses the strategic use of pansexual and queer identity labels and their relation to current health-related research. The author outlines the scant research on pansexual and queer mental health disparities and offers considerations for moving a larger research agenda forward.
Stress cardiac MRI in stable coronary artery disease
Authors: Ge Yin , Deva Djeven P. , Connelly Kim A. , Yan Andrew T. 
Published: July 2020

Purpose of review
Non-invasive testing is often the first step in the evaluation of stable coronary artery disease (CAD). Stress cardiac magnetic resonance imaging (CMR) is an established modality with high diagnostic accuracy and prognostic value. This review will focus on the recent advances in understanding how stress CMR can help guide patient care.

Recent findings
Diagnostic accuracy of stress CMR has been validated against coronary angiography with fractional flow reserve (FFR) in patients with stable CAD. Large registry data have shown stress CMR to have important prognostic importance and that its cost-effectiveness compares favorably to alternatives. In patients with stable CAD, guidance using a CMR based strategy led to equivalent outcomes when compared to coronary angiography with FFR.

Summary
In persons with stable CAD, Stress CMR is an accurate and cost-effective imaging modality that should be considered in patients at intermediate pre-test probability of CAD. Prognostic studies have shown it to have excellent negative predictive value and that it can safely serve as a “gatekeeper” for invasive angiography.
Nocturnal blood pressure: the dark side of white-coat hypertension
Authors: Cuspidi Cesare , Paoletti Federico , Tadic Marijana , Sala Carla , Gherbesi Elisa , Dell’Oro Raffaella , Grassi Guido , Mancia Giuseppe 
Published: July 2020

Aim:
The impact of defining white-coat hypertension (WCH) and white-coat uncontrolled hypertension (WCUH) based on daytime and night-time thresholds of ambulatory blood pressure (ABP), instead of 24-h mean value, is unclear. We aimed to reclassify BP status according to both diurnal and nocturnal thresholds in a large sample of hypertensive patients seen in a specialist center and previously classified as WCH and WCUH based on 24-h BP values.

Methods:
A data-base of 7353 individual 24-h ABP monitoring (ABPM) from untreated and treated hypertensive individuals with office BP at least 140 mmHg and/or 90 mmHg was analysed and a subset of 3223 patients characterized by mean 24-h BP less than 130/80 mmHg (i.e. WCH and WCUH) was included in the present analysis.

Results:
As many as 1281 patients were classified as WCH and 1942 as WCUH. Among them, elevated out-of-office BP according to night-time threshold (i.e. ≥120/70 mmHg) was found in about 30% of cases. In particular, prevalence rates of nocturnal hypertension were 26.9% in WCH and 31.8% in WCUH. Isolated daytime hypertension (i.e. ≥135/85 mmHg) was detected in an additional 4% of individuals.

Conclusion:
Classification of WCH and WCUH based on mean 24-h BP thresholds does not allow to detect an adverse BP phenotype, such as nocturnal hypertension in a large fraction of untreated and treated patients.