bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Experimental and Statistical Analysis of Double Slope Single Basin Solar Still in Active and Passive Mode with Different Water Depth.
Authors: Prasad Rakesh , Singh Devendra , Sharma Ajay 
Published: December 2019

Abstract
In the present work, experimental work on double slope single-basin still is investigated. The statistical analysis shows the effect of various factors related to the efficiency of still. The water level in the basin investigated at 10 cm, 6 cm and 2 cm depth. The process temperature TW, TG and TB were recorded one each day. The still is used in the Agra city climate. The mode of operation affects its water yield as an active mode of operation produces more water yield than a passive mode of operation. In the statistical analysis R2=99.29 (passive mode) and R2=99.11 (active mode) recommend the satisfactory agreement of the factorial design regression model.
The Study of Parametric Factor in Attic Space for Winter Season
Authors: Gupta Anuj , Thakur Harishchandra 
Published: December 2019

Abstract
This research investigates the structure of an attic space from the perspective of thermal engineering. It helps in understanding the variation of flow and field strength due to natural convection. A critical review concludes that heat transfer inside a building is most complex for the attic space. The study examines the effect of the parametric factor on natural convection. It includes analysis for the winter conditions. The numerical model is simulated for different values of Rayleigh Number (Ra = 104
− 106) using ANSYS 19 considering air with Prandtl number 0.71. With the assumptions of having the uniform temperature over the wall and no-slip condition for walls, Results are demonstrated with the use of Isotherm, Streamline and Nusselt number. With the finding of plots, the study argues that S/L ratio of 0.8 is recommended for the attic space having good thermal performance.
Design and analysis of thin walled composite beam
Authors: Sahu Shiva , kumar singh Mukesh 
Published: December 2019

Abstract
In present research composite beam of Glass/Epoxy has been taken for the analysis of failure bending moment by Finite Element Analysis. The orientation of the plies are oriented as [0°/-45°/45°/90°/90°/45°/-45°/0°] named as S1 are tested and analyzed with the Tsai- Wu failure criteria. It is found that the sample S1 composite having low load carrying capacity and bending moment. Furthermore, another ply are oriented as [0°/90°/0°/90°/90°/0°/90°/0°] named as S4 are tested and analyzed Tsai-Wu failure criteria under same loading condition. It is found that the sample S4 composite having higher load carrying capacity and bending moment. The composite materials such as the Graphite/Epoxy and the Boron/Epoxy have also been considered for the analysis with the same boundary condition as the Glass/Epoxy. Comparative result shows that the Boron/Epoxy having highest load carrying capacity and bending moment as compare to the Graphite/Epoxy and the Glass/Epoxy. The results obtained from the proposed method having good agreement with the results obtained from the previous research.
Printed graphene/WS2 battery-free wireless photosensor on papers
Authors: Leng Ting , Parvez Khaled , Pan Kewen , Ali Junaid , McManus Daryl , Novoselov Kostya S , Casiraghi Cinzia , Hu Zhirun 
Published: December 2019

Abstract
Screen-printed graphene near field communication (NFC) tag antenna is integrated with inkjet-printed WS2 photodetector on paper substrate to fabricate battery-free wireless photosensor. A sequential multi-stack printing is employed for the wireless photosensor fabrication: the NFC tag antenna is first screen-printed with graphene conductive ink and then the photodetector is inkjet-printed with transition metal dichalcogenides (TMDs) WS2 ink as photoactive component. High responsivity and sensitivity are observed for the WS2 photodetector, which acts as photoactive thermistor of the NFC sensor IC chip. The highly conductive graphene nanoflakes ink enables the screen-printed graphene NFC tag antenna to withdraw sufficient power wirelessly from the reader to power the sensor IC chip. This work demonstrates a prospective approach to manufacture 2D materials enabled electronics where the electronic circuits (normally having a large size) can be realized by mass production screen printing and the sensing component (normally having a small size) can be produced by inkjet printing, enabling low cost and simple fabrication methods, compatible with flexible substrates such as paper.
Mass spectrometry of carbohydrate-protein interactions on a glycan array conjugated to CVD graphene surfaces
Authors: Merino Juan Pedro , Serna Sonia , Criado Alejandro , Centeno Alba , Napal Ilargi , Calvo Javier , Zurutuza Amaia , Reichardt Niels , Prato Maurizio 
Published: December 2019

Abstract
Mass spectrometry (MS) is a valuable tool for functional genomic, proteomic, and glycomic studies. In particular, the combination of MS with microarrays is a powerful technique for analyzing the activity of carbohydrate processing enzymes and for the identification of carbohydrate-binding proteins (lectins) in complex matrices. On the other hand, graphene exhibits high desorption/ionization efficiency, good conductivity and optical transparency, specifications of a high-performance component for matrix-assisted laser desorption/ionization (MALDI) platforms. Besides, the chemical functionalization of graphene increases the adsorption capability of functional biomolecules (e.g. receptors), resulting in very stable interfaces. Taking advantage of the properties of graphene, we developed several modified chemical vapor deposited graphene (CVDG)-based glycan arrays on different substrates including ITO and bare glass, as a potential sensing platform for carbohydrate-lectin interactions, which are involved in a plethora of biological processes. The glycan arrays were fully characterized by MALDI-MS analysis and, in some cases, optical microscopy.
Using non-homogeneous point process statistics to find multi-species event clusters in an implanted semiconductor
Authors: Stockbridge K , Chick S , Crane E , Fisher A , Murdin B N 
Published: December 2019

Abstract
The Poisson distribution of event-to-

i
th

-nearest-event radial distances is well known for homogeneous processes that do not depend on location or time. Here we investigate the case of a non-homogeneous point process where the event probability (and hence the neighbour configuration) depends on location within the event space. The particular non-homogeneous scenario of interest to us is ion implantation into a semiconductor for the purposes of studying interactions between the implanted impurities. We calculate the probability of a simple cluster based on nearest neighbour distances, and specialise to a particular two-species cluster of interest for qubit gates. We show that if the two species are implanted at different depths there is a maximum in the cluster probability and an optimum density profile.
Curing perovskites—a way towards control of crystallinity and improved stability
Authors: Seewald Tobias , Schütz Emilia R , Ebenhoch Carola , Schmidt-Mende Lukas 
Published: December 2019

Abstract
Power conversion efficiencies of lead halide perovskite solar cells have rapidly increased in the decade since their emergence, reaching 25% this year. However, reliable film uniformity and device stability remain hard to achieve and often require precise compliance with complicated protocols, which hampers upscaling towards industrial applications. Here, we explore the potential of an alternative route towards high-quality perovskite films: The reaction between a pre-existing perovskite film and methylamine (MA) gas has been shown to possess the striking ability to both improve film morphology and increase grain size drastically, boosting device performance. This post-deposition treatment could provide the means to decouple film quality from the initial deposition process, thus promising to facilitate upscaling and lowering production costs. Furthermore, such MA gas treatments show great promise regarding the stability of fabricated devices, as they open up the opportunity to reduce or even eliminate the adverse role of grain boundaries in film degradation.
BRAF, KIT, and NRAS Mutations of Acral Melanoma in White Patients
Authors: Dika Emi , Veronesi Giulia , Altimari Annalisa , Riefolo Mattia , Ravaioli Giulia Maria , Piraccini Bianca Maria , Lambertini Martina , Campione Elena , Gruppioni Elisa , Fiorentino Michelangelo , Melotti Barbara , Ferracin Manuela , Patrizi Annalisa 
Published: December 2019

Abstract

Objectives
Malignant acral melanoma (AM) is relatively infrequent in white patients. Molecular investigations have returned variable results regarding the mutational pattern. We sought to describe the mutation profile and clinicopathologic features of AM.

Methods
We investigated BRAF, KIT, and NRAS mutational status in a series of 31 AM samples from white patients.

Results
Nodular melanoma was the most common histopathologic subtype (48.4%), followed by acral lentiginous melanoma (25.8%) and superficial spreading melanoma (25.8%). BRAF, KIT, and NRAS mutational rates were 12.9%, 17.2%, and 30.0%, respectively. We observed significant associations between KIT mutational status and a thinner Breslow thickness compared with wild-type (WT) status (P = .002), NRAS mutation status and younger age compared with WT. In patients presenting at least one mutation, triple-WT patients presented metastases most frequently.

Conclusions
Although these data represent preliminary results, better knowledge of tumor biology and prognosis of AM can support the clinical approach and follow-up.
Characterizing Cross-Culturally Relevant Metrics of Stigma Among Men Who Have Sex With Men Across 8 Sub-Saharan African Countries and the United States
Authors: Augustinavicius Jura L , Baral Stefan D , Murray Sarah M , Jackman Kevon , Xue Qian-Li , Sanchez Travis H , Nowak Rebecca G , Crowell Trevor A , Zlotorzynska Maria , Olawore Oluwasolape , Lyons Carrie E , Njindam Iliassou M , Tamoufe Ubald , Diouf Daouda , Drame Fatou , Kouanda Seni , Kouame Abo , Charurat Man E , Anato Simplice , Mothopeng Tampose , Mnisi Zandile , Kane Jeremy C 
Published: December 2019

Abstract
Overcoming stigma affecting gay, bisexual, and other men who have sex with men (MSM) is a foundational element of an effective response to the human immunodeficiency virus (HIV) pandemic. Quantifying the impact of stigma mitigation interventions necessitates improved measurement of stigma for MSM around the world. In this study, we explored the underlying factor structure and psychometric properties of 13 sexual behavior stigma items among 10,396 MSM across 8 sub-Saharan African countries and the United States using cross-sectional data collected between 2012 and 2016. Exploratory factor analyses were used to examine the number and composition of underlying stigma factors. A 3-factor model was found to be an adequate fit in all countries (root mean square error of approximation = 0.02–0.05; comparative fit index/Tucker-Lewis index = 0.97–1.00/0.94–1.00; standardized root mean square residual = 0.04–0.08), consisting of “stigma from family and friends,” “anticipated health-care stigma,” and “general social stigma,” with internal consistency estimates across countries of α = 0.36–0.80, α = 0.72–0.93, and α = 0.51–0.79, respectively. The 3-factor model of sexual behavior stigma cut across social contexts among MSM in the 9 countries. These findings indicate commonalities in sexual behavior stigma affecting MSM across sub-Saharan Africa and the United States, which can facilitate efforts to track progress on global stigma mitigation interventions.
Capsulectomy, Implant Exchange, and Placement of Acellular Dermal Matrix Is Effective in Treating Capsular Contracture in Breast Augmentation Patients
Authors: Wagner Douglas S , Mirhaidari Shayda J 
Published: December 2019

Abstract

Background
Capsular contracture is a common complication of breast augmentation surgery and many techniques to prevent and treat it have been suggested with inconsistent or variably effective results.

Objectives
The aim of this paper was to describe a protocol for treating established capsular contracture after breast augmentation with a low recurrence rate.

Methods
From January 2009 to December 2012, 79 previous bilateral breast augmentation patients presented for treatment of established capsular contracture. There were 135 breasts with capsular contracture: 56 were bilateral and 23 were unilateral. Ten patients opted for no treatment; 2 patients opted for implant removal. Twenty-four were treated with the ICES (implant exchange, capsulectomy, and possible exchange of site) protocol and 43 were treated with the SPICES (Strattice placement in the reconstructive position, implant exchange, capsulectomy, and possible exchange of site) protocol.

Results
The 24 patients treated with the ICES protocol had a recurrent capsular contracture rate of 15%. The 43 patients treated with the SPICES protocol had a 2.7% recurrent capsular contracture incidence and an 2.7% complication rate.

Conclusions
Capsular contracture after breast augmentation, whether primary or recurrent, can be successfully treated with the SPICES protocol.

Level of Evidence: 4
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness
Authors: Huang Gena , Song Chen , Wang Ning , Qin Tao , Sui Silei , Obr Alison , Zeng Li , Wood Teresa L , Leroith Derek , Li Man , Wu Yingjie 
Published: December 2019

AbstractThe insulin receptor gene (INSR) undergoes alternative splicing to give rise to two functionally related, but also distinct, isoforms IR-A and IR-B, which dictate proliferative and metabolic regulations, respectively. Previous studies identified the RNA-binding protein CUGBP1 as a key regulator of INSR splicing. In this study, we show that the differential splicing of INSR occurs more frequently in breast cancer than in non-tumor breast tissues. In breast cancer cell lines, the IR-A:IR-B ratio varies in different molecular subtypes, knockdown or overexpression of CUGBP1 gene in breast cancer cells altered IR-A:IR-B ratio through modulation of IR-A expression, thereby reversed or enhanced the insulin-induced oncogenic behavior of breast cancer cells, respectively. Our data revealed the predominant mitogenic role of IR-A isoform in breast cancer and depicted a novel interplay between INSR and CUGBP1, implicating CUGBP1 and IR-A isoform as the potential therapeutic targets and biomarkers for breast cancer.
Civil Society Must Be Defended: Misinformation, Moral Panics, and Wars of Restoration
Authors: Bratich Jack 
Published: December 2019

AbstractIn this article, I propose that we think of the recent concern over fake news, misinformation, disinformation, and conspiracy theories as a moral panic. I revisit Stuart Hall and his co-authors’ concept, updating it in two ways. First, I focus on how the current panic has altered what they called “primary definers” (which now includes professional journalism, as a result of their own waning authority). Second, the new alliance of panic actors (journalism, technology companies, intelligence agencies, politicians, civil society organizations) are expressions of a crisis policing that is now martialized. I assess this new nexus in terms of a breakdown of civil peace into outright hostilities; as a counterinsurgency operation. I draw on Michel Foucault’s strategic analysis of power and society that challenges boundaries between politics and war. This nexus is waging what I call a war of restoration, one that has significant implications for dissent and oppositional knowledges.
Breaking the silence: community radio, women, and empowerment
Authors: Rimmer Annette 
Published: December 2019

Abstract
The article argues that community development work, in the form of feminist pedagogy and community radio, can engage more women in technological roles, aid women’s confidence and mental health and possibly, improve diversity in mainstream media. In UK media, corporations are heavily criticized for their under and misrepresentation of women and, in general, their inability to engage with excluded groups. The BBC’s strategic aim is to improve inclusion and diversity by 2020. The article asserts the value of community development methods in efforts to address this. It explores concepts of voice poverty and empowerment through analysis of the narratives of twelve female community radio volunteers in Northern England.
Using Freire’s (1972) notion of ‘culture of silence’ and against the backdrop of gender inequality, the article clarifies the nature of community radio and employs a variety of literatures to understand how a feminist pedagogy (hooks, 1994) and an intersectional approach (Crenshaw, 1989) might be useful in media. It builds from Stuart Hall’s contention that media and cultural spaces can be powerful sites of social action.
Analysis of participant accounts indicates that community radio is a site of diverse identities, laughter, dialogue, raised consciousness, and conflict. This confronts not only the orthodoxy of young white, male-dominated media but also challenges romantic notions of community harmony and happiness by recognizing inherent tensions within prevailing conceptions of womanhood and within and between communities.
The article foregrounds evidence from the majority world, where community radio is well documented as giving voice to invisiblized women, and concludes with an argument for further exploration of this highly symbolic dimension of empowerment, whereby women overcome technological fears and break their silence by broadcasting diverse voices. The project challenges UK commercial and public broadcasters to learn from the global south that community radio is an effective method of development with potential to enrich the mainstream media world.
Clinical Implications of Microbiologic Treatment Failure in the Setting of Clinical Cure of Bacterial Pneumonia
Authors: Albin Owen R , Henig Oryan , Patel Twisha S , Valley Thomas S , Pogue Jason M , Petty Lindsay A , Mills John P , Brancaccio Adamo , Martin Emily T , Kaye Keith S 
Published: December 2019

Abstract

Background
Microbiologic cure is a common outcome in pneumonia clinical trials, but its clinical significance is incompletely understood.

Methods
We conducted a retrospective cohort study of adult patients hospitalized with bacterial pneumonia who achieved clinical cure. Rates of recurrent pneumonia and death were compared between patients with persistent growth of the index pathogen at the time of clinical cure (microbiologic failure) and those with pathogen eradication (microbiologic cure).

Results
Among 441 patients, 237 experienced microbiologic cure and 204 experienced microbiologic failure. Prevalences of comorbidities, ventilator dependence, and severity of acute illness were similar between groups. Patients with microbiologic failure experienced significantly higher rates of recurrent pneumonia or death following clinical cure than patients with microbiologic cure, controlling for comorbid conditions, severity of acute illness, appropriateness of empiric antibiotics, intensive care unit placement, tracheostomy dependence, and immunocompromised status (90-day multivariable adjusted odds ratio [OR], 1.56; 95% confidence interval [CI], 1.04–2.35). This association was observed among patients with pneumonias caused by Staphylococcus aureus (90-day multivariable adjusted OR, 3.69; 95% CI, 1.73–7.90). A trend was observed among pneumonias caused by nonfermenting gram-negative bacilli, but not Enterobacteriaceae or other pathogens.

Conclusions
Microbiologic treatment failure was independently associated with recurrent pneumonia or death among patients with bacterial pneumonia following clinical cure. Microbiologic cure merits further study as a metric to guide therapeutic interventions for patients with bacterial pneumonia.
Early Evidence of Inactivated Enterovirus 71 Vaccine Impact Against Hand, Foot, and Mouth Disease in a Major Center of Ongoing Transmission in China, 2011–2018: A Longitudinal Surveillance Study
Authors: Head Jennifer R , Collender Philip A , Lewnard Joseph A , Skaff Nicholas K , Li Ling , Cheng Qu , Baker Julia M , Li Charles , Chen Dehao , Ohringer Alison , Liang Song , Yang Changhong , Hubbard Alan , Lopman Benjamin , Remais Justin V 
Published: December 2019

Abstract

Background
Enterovirus 71 (EV71) is a major causative agent of hand, foot, and mouth disease (HFMD), associated with severe manifestations of the disease. Pediatric immunization with inactivated EV71 vaccine was initiated in 2016 in the Asia-Pacific region, including China. We analyzed a time series of HFMD cases attributable to EV71, coxsackievirus A16 (CA16), and other enteroviruses in Chengdu, a major transmission center in China, to assess early impacts of immunization.

Methods
Reported HFMD cases were obtained from China’s notifiable disease surveillance system. We compared observed postvaccination incidence rates during 2017–2018 with counterfactual predictions made from a negative binomial regression and a random forest model fitted to prevaccine years (2011–2015). We fit a change point model to the full time series to evaluate whether the trend of EV71 HFMD changed following vaccination.

Results
Between 2011 and 2018, 279 352 HFMD cases were reported in the study region. The average incidence rate of EV71 HFMD in 2017–2018 was 60% (95% prediction interval [PI], 41%–72%) lower than predicted in the absence of immunization, corresponding to an estimated 6911 (95% PI, 3246–11 542) EV71 cases averted over 2 years. There were 52% (95% PI, 42%–60%) fewer severe HFMD cases than predicted. However, the incidence rate of non-CA16 and non-EV71 HFMD was elevated in 2018. We identified a significant decline in the trend of EV71 HFMD 4 months into the postvaccine period.

Conclusions
We provide the first real-world evidence that programmatic vaccination against EV71 is effective against childhood HFMD and present an approach to detect early vaccine impact or intended consequences from surveillance data.
Vascular pressure bands on high-resolution esophageal manometry with impedance studies
Authors: Lis Steffen , Vachhani Herit , Tanner Samuel , Leopold Andrew , Zitomer Samantha , Bhuta Rajiv , Schey Ron , Malik Zubair , P  Parkman Henry 
Published: December 2019

ABSTRACT
Horizontal pressure bands on high-resolution esophageal manometry with impedance (HREMI) tracings are often seen and thought to be due to cardiovascular structures compressing the esophagus. The aim of this study was to determine the prevalence and location of vascular pressure bands on HREMI studies and correlate these pressure bands to bolus clearance. HREMI studies in supine and upright positions from patients and normal volunteers were reviewed. Pressure bands were defined as bands of horizontal pressure greater than the 20 mmHg isobaric contour. Each swallow was reviewed with impedance to determine if bolus transit was impaired by the band. 38.6% of 251 patients and 36.4% of 11 normal controls had a pressure band present. There were a greater number of bands in supine versus upright position (patients: 130 vs. 25, P &lt; 0.001 and controls: 6 vs. 1). Patients with pressure bands had similar demographics (age, gender, BMI) compared to those without. Average distal contractile integral of bands was greater in supine compared to upright (133 ± 201 vs. 60 ± 148 mmHg cm s, P &lt; 0.05). Bands were commonly located clustered at 46 and 72% of esophageal length. Bolus transit was impaired by bands in 20.4% of supine and 14.0% of upright swallows. Vascular pressure bands can have a prominent appearance on HREMI studies, present in, being more prevalent and having greater pressure in the supine than the upright position. These vascular bands, when present, may impair esophageal transit.