bluuebunny/crossref_metadata_2025_split huggingface dataset:
Data-driven remanufacturing assembly intelligent control system for improving resource and production efficiency
Authors: Liu Conghu , Cai Wei , Zhu Guang , Gao Mengdi 
Published: May 2020

Abstract
Remanufacturing has been considered to be one of the most effective ways to deal with sustainable manufacturing. This paper proposes a data-driven intelligent control system for improving the production and resource efficiency of the remanufacturing assembly systems. First, an optimization model of the reassembly scheme is established for minimizing the quality loss and comprehensive cost. Remanufactured parts are measured, grouped, coded, and dimensional chain calculated based on the data acquisition and processing technology. Then, an intelligent control method for remanufacturing assembly process is proposed, which is a real-time monitoring and dynamic compensation response to abnormal quality to achieve intelligent control of reassembly process. The intelligent control information system that include information perception and fusion technology, real-time monitoring and dynamic compensation architecture are studied and implemented through data-driven technologies. Finally, a case study illustrates its practicability offering a technical support for sustainability of remanufacturing.
Applying the health belief model to identify predictors of self-perceived risk of HIV infection among undergraduates in mainland China
Authors: Ruan Fang , Fu Guochen , Zhou Mingyu , Li Xin , Chen Yuhua , Li Yilin , Lu Can , Ke Shuhui , Pan Mengge , Li Yajie , Zhang Yu , Shi Bin , Gong Qinxin , Fu Zihan , Shi Ting , Liu Yusi , Liu Fuqiang , Zhan Jihong , wang Junfang 
Published: May 2020

Abstract
Objective This cross-sectional study aimed to identify predictors of self- perceived risk of HIV infection among undergraduates in mainland China, based on the health belief model.Methods A self-administered questionnaire survey method was used to collect information from 10665 eligible undergraduates across the whole country (except for Tibet). Multivariate Logistic regression analysis was chosen to explore the predictors of self-perceived risk of HIV infection.Results Approximately half (48.2%) of the undergraduates perceived themselves to be at risk of contracting HIV, yet only 8.9% reported to engage in risky sexual behaviors. After controlling for potential confounders, males [adjusted odd ratio (AOR)=0.72, 95% confidence interval (CI)=0.66-0.77], those residing in urban areas (AOR=0.86, 95% CI= 0.79-0.93), having higher levels of condom use self-efficacy (AOR=0.64, 95% CI=0.58-0.69) and knowing the national AIDS policy (AOR=0.68, 95% CI=0.62-0.74) were less likely to perceive themselves to be at risk of acquiring HIV. Conversely, freshmen (AOR=1.27, 95% CI=1.16-1.38), non-heterosexuals (AOR=1.57, 95% CI=1.39-1.77), and those who had expressed less stigma towards people living with HIV (PLHIV) (AOR=1.25, 95% CI=1.15-1.35) and had the intention of utilizing voluntary counseling and testing (VCT) services (AOR=1.29, 95% CI=1.16-1.43) perceived themselves to be at increased risk for HIV infection.Conclusions Undergraduates tended to overestimate their own risk of acquiring HIV infection. In order to help undergraduates accurately assess their risk of being infected with HIV and effectively avoid risk, a comprehensive intervention measure should be taken to target females, non-heterosexuals, freshmen and those residing in rural areas, raise their awareness of the national AIDS policy, relieve their stigma against PLHIV, improve their condom use self-efficacy and provide VCT services in college campus.
Reduced child maltreatment prevention service case openings during COVID-19
Authors: Whaling Kelly , Sarkissian Alissa Der , Larez Natalie A. , Sharkey Jill D. , Allen Michael A. , Nylund-Gibson Karen 
Published: May 2020

Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19), is a novel virus that has swept the world causing illness and death. Youth are at a heightened risk of experiencing increased rates of abuse given necessary measures required to slow the spread of the virus (e.g., indefinite school closures). We analyzed data from New York City’s Administration for Children’s Services (ACS) to investigate the frequency of child maltreatment prevention service case openings during this time of unprecedented stress. Two descriptive investigations were conducted. An examination of trend lines demonstrated that for 2013-2019, New York City’s new prevention case openings have consistently peaked in the month of March, for all seven years. New prevention case service openings in March 2020 do not peak, as they do in the preceding seven years. An independent samples t-test indicated that the frequency of case openings of March 2020 is significantly different than the frequency of case openings in March 2013-2019. Further, a Poisson regression model estimated that the odds of opening a new child maltreatment prevention case post-COVID-19 are 179% lower than opening a new child maltreatment case pre-COVID-19 (OR = -0.79, p < .001). These findings highlight the necessity of future research and innovation regarding child maltreatment prevention and intervention services during a global pandemic. This study has important implications for identification, prevention, and documentation for current support, and recommendations for local governments, community members, and practitioners are provided.
COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms
Authors: Malone Robert W. , Tisdall Philip , Fremont-Smith Philip , Liu Yongfeng , Huang Xi-Ping , White Kris M. , Miorin Lisa , Olmo Elena Moreno Del , Alon Assaf , Delaforge Elise , Hennecker Christopher D. , Wang Guanyu , Pottel Joshua , Bona Robert , Smith Nora , Hall Julie M. , Shapiro Gideon , Clark Howard , Mittermaier Anthony , Kruse Andrew C. , García-Sastre Adolfo , Roth Bryan L. , Glasspool-Malone Jill , Francone Victor , Hertzog Norbert , Fremont-Smith Maurice , Ricke Darrell O. 
Published: May 2020

Abstract
SARS-CoV-2 infection is required for COVID-19, but many signs and symptoms of COVID-19 differ from common acute viral diseases. Currently, there are no pre- or post-exposure prophylactic COVID-19 medical countermeasures. Clinical data suggest that famotidine may mitigate COVID-19 disease, but both mechanism of action and rationale for dose selection remain obscure. We explore several plausible avenues of activity including antiviral and host-mediated actions. We propose that the principal famotidine mechanism of action for COVID-19 involves on-target histamine receptor H2 activity, and that development of clinical COVID-19 involves dysfunctional mast cell activation and histamine release.
Fuzzy AHP-TOPSIS multi-criteria decision analysis applied to the Indus Reservoir system in Pakistan
Authors: Janjua Shahmir , Hassan Ishtiaq 
Published: May 2020

Abstract
The ranking of the reservoirs in Pakistan is an important decision and it has a vital impact on the sustainability of the region and the economic operation of the reservoir. The reservoirs ranking is a vital problem which involves multi-criteria decision-making. The framework proposed in this paper involves the fuzzy AHP-TOPSIS method for the ranking of reservoirs in Pakistan. Potential feasible locations are identified from the Water and Power Development Authority, Pakistan. Weight calculation for the criteria is done by the fuzzy AHP method, which is a multi-criteria decision-making method. In order to model the fuzziness, equivocacy, incomplete knowledge and ambiguity, the fuzzy AHP is used. Furthermore, in order to rank the selected reservoirs based on their performance, the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) is applied, which is a multicriteria decision making method. We demonstrate the application of the above-mentioned methods to the case study of the Indus Reservoir system in Pakistan. A decision support tool is provided for the decision makers in this paper to manage, evaluate and rank the planned reservoirs in the Indus River.
Human Health Effects of Lactose Consumption as a Food and Drug Ingredient
Authors: Seoane Rafael G. , Garcia-Recio Verónica , Garrosa Manuel , Rojo María Á. , Jiménez Pilar , Girbés Tomás , Cordoba-Diaz Manuel , Cordoba-Diaz Damián 
Published: May 2020

:
Lactose is a reducing sugar consisting of galactose and glucose, linked by a β (1→4) glycosidic bond,
considered as an antioxidant due to its α-hydroxycarbonyl group. Lactose is widely ingested through the milk and
other unfermented dairy products and is considered to be one of the primary foods. On the other hand, lactose is
also considered as one of the most widely used excipients for the development of pharmaceutical formulations. In
this sense, lactose has been related to numerous drug-excipient or drug-food pharmacokinetic interactions.

:
Intolerance, maldigestion and malabsorption of carbohydrates are common disorders in clinical practice, with
lactose-intolerance being the most frequently diagnosed, afflicting 10% of the world’s population. Four clinical
subtypes of lactose intolerance may be distinguished, namely lactase deficiency in premature infants, congenital
lactase deficiency, adult-type hypolactasia and secondary lactase intolerance. An overview of the main uses of
lactose in human nutrition and in the pharmaceutical industry and the problems derived from this circumstance
are described in this review.
Effect of Proton-Pump Inhibitors on Glucose and Insulin Metabolism on Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Sánchez-García Adriana , Simental-Mendía Mario , Simental-Mendía Luis E. 
Published: May 2020

Background:
Some studies have revealed an improvement in glucose metabolism after proton-pump
inhibitors (PPI) therapy; however, this evidence is inconclusive and limited.

Objective:
The study aimed to examine the effect of PPI on glucose and insulin metabolism in patients with type
2 diabetes through a systematic review and meta-analysis.

Methods:
Only randomized controlled trials evaluating the impact of PPI on glucose or insulin concentrations in
type 2 diabetes were searched in PubMed-Medline, SCOPUS, Web of Science and Google Scholar databases. A
meta-analysis was conducted using a random-effects model and generic inverse variance method. Sensitivity
analysis was performed using the leave-one-out method.

Results:
Meta-analysis revealed no significant effect of PPI intervention on fasting glucose (mean difference
[MD] -11.42 [95% CI, -29.68 to 6.83], I2 = 80%, p = 0.22), fasting insulin (MD 1.51 [95% CI, -0.36 to 3.37], I2 =
32%, p = 0.11), HOMA-IR (MD -0.16 [-0.98 to 0.65], I2 = 0%, p = 0.70), HOMA-β (MD 19.97 [-21.59 to 61.52],
I2 = 71%, p = 0.35), and HbA1c concentrations (MD -0.34 [-0.99 to 0.31], I2 = 89%, p = 0.30).

Conclusion:
The treatment with PPI, in the short term, had no significant effects on glucose and insulin metabolism
in patients with type 2 diabetes.
Oral Health-Related Quality of Life during Pregnancy: A Systematic Review
Authors: Fakheran Omid , Saied-Moallemi Zahra , Khademi Abbasali , Sahebkar Amirhossein 
Published: May 2020

Objective:
High prevalence of Dental and periodontal problems during the gestation period may have a
negative effect on oral health-related quality of life (OHRQoL) in pregnant women. This systematic review aimed
to perform a quality assessment and provide a critical overview of the current research available on OHRQoL in
pregnant women.

Methods:
For this systemic review, all original and peer-reviewed human studies, which investigated OHRQoL
of women during pregnancy or post- partum period, were searched. Studies were screened in title and abstract for
the relevance by two independent investigators. Methodological quality was assessed using modified items recommended
by the Newcastle–Ottawa Scale for observational studies.

Results:
All of the eight included studies had a cross-sectional design. Meta-analysis was not possible due to the
heterogeneity of key aspects among the included studies. Thus, the data from the studies were evaluated qualitatively.
The overall risk of bias of the included studies was low.

Conclusion:
The main conclusion of this review is that the presence of signs and symptoms of dental and gingival
disease negatively affects the self-perception of OHRQoL in pregnant women. The most affected domains of
OHRQoL in pregnant women were related to mental and psychological discomfort, followed by physical and
functional problems.
Modulation of the Drug Resistance by Platonia insignis Mart. Extract, Ethyl Acetate Fraction and Morelloflavone/Volkensiflavone (Biflavonoids) in Staphylococcus aureus Strains Overexpressing Efflux Pump Genes
Authors: e Silva Andressa K.F. , dos Reis Antonielly C. , Pinheiro Emanuelly E.A. , de Sousa Jonas N. , de Alcântara Oliveira Felipe A. , Moura Arkellau K.S. , de Sousa L. Neto José , das Graças L. Citó Antonia M. , Siqueira-Júnior José P. , Kaatz Glenn W. , Barreto Humberto M. 
Published: May 2020

Background:
Microbial resistance to antibiotics is a global public health problem, which requires urgent
attention. Platonia insignis is a native species from the eastern Brazilian Amazon, used in the treatment of burns and
wounds.

Objectives:
To evaluate the antimicrobial activity of the hydroalcoholic extract of P. insignis (PIHA), the ethyl acetate
fraction (PIAE), and its subfraction containing a mixture of biflavonoids (BF). Moreover, the effect of these
natural products on the antibiotic activity against S. aureus strains overexpressing efflux pump genes was also evaluated.

Methods:
Minimal inhibitory concentrations were determined against different species of microorganisms. To evaluate
the modulatory effect on the Norfloxacin-resistance, the MIC of this antibiotic was determined in the absence and
presence of the natural products at subinhibitory concentrations. Inhibition of the EtBr efflux assays were conducted
in the absence or presence of natural products.

Results:
PIHA showed a microbicidal effect against S. aureus and C. albicans, while PIAE was bacteriostatic for S.
aureus. PIAE and BF at subinhibitory concentrations were able to reduce the MIC of Norfloxacin acting as modulating
agents. BF was able to inhibit the efflux of EtBr efflux in S. aureus strains overexpressing specific efflux pump
genes.

Conclusion:
P. inignisis, a source of efflux pump inhibitors, including volkensiflavone and morelloflavone, which
were able to potentiate the Norfloxacin activity by NorA inhibition, being also able to inhibit QacA/B, TetK and
MsrA. Volkensiflavone and morelloflavone could be used as an adjuvant in the antibiotic therapy of multidrug resistant
S. aureus strains overexpressing efflux pumps.
Anti-vascular Endothelial Growth Factor Antibody Limits the Vascular Leakage and Decreases Subretinal Fibrosis in a Cynomolgus Monkey Choroidal Neovascularization Model
Authors: Inagaki Satoshi , Shimazawa Masamitsu , Hamaguchi Koji , Otsu Wataru , Araki Tomoaki , Sasaki Yuji , Numata Yosuke , Tsusaki Hideshi , Hara Hideaki 
Published: May 2020

Objective:
This study was conducted to evaluate the effects of anti-vascular endothelial
growth factor (VEGF) antibody (bevacizumab) on vascular leakage and fibrosis in a monkey
choroidal neovascularization (CNV) model. The relationship between fibrotic tissue and subretinal
hyper-reflective material (SHRM), in optical coherence tomography (OCT) images, was also investigated.

Methods:
Experimental CNV was induced in male cynomolgus monkeys by laser photocoagulation.
Intravitreal injection of bevacizumab at 0.5 mg/eye/dosing was initiated 2 weeks before or after laser
irradiation and thereafter, conducted intermittently at 2- or 3-week intervals. Fluorescein fundus angiography
(FA) and OCT imaging were conducted weekly from 2 to 7 weeks after laser irradiation.
CNV leakage was evaluated by an established grading method using FA images. To assess the fibrosis
and scarring, Masson’s trichrome specimens of each CNV lesion were prepared, and morphometric
analysis was conducted using an image analysis software.

Results:
The effects of bevacizumab on vascular leakage were shown using an established evaluation
method. Morphometric analysis of Masson’s trichrome-stained (MT) specimens revealed that
collagen fiber synthesis was suppressed by bevacizumab pre-treatment (-29.2%) or post-treatment
(-19.2%). SHRM was detected in OCT images in a monkey CNV model, and a significant correlation
between the SHRM area in the OCT images and the collagen fiber area in the MT specimens
was noted.

Conclusion:
In the established cynomolgus monkey CNV model, bevacizumab prevented blood
leakage but could not completely suppress fibrosis. SHRM in the OCT images reflected retinal
fibrous tissue in a laser-induced CNV monkey model. This model might be useful for elucidating the
pathology and development therapy for neovascularization or fibrosis.
Frequency of Iron Uptake Proteins Related Genes Among Klebsiella pneumoniae Isolates
Authors: Elhaki Tahereh , Gheysarzadeh Ali , Sadeghifard Nourkhoda , Pakzad Iraj , Behrouzi Ava , Taherikalani Morovat , Jalilian Farid A. , Tabasi Mohsen , Azizian Reza 
Published: May 2020

Aims:
The present study aimed to evaluate Iron uptake protein-related genes in clinical and environmental Klebsiella pneumoniae isolates.

Background:

Klebsiella pneumoniae as an opportunistic pathogen cause infections in immunocompromised patients. Iron uptake systems play an important role in the pathogenesis of Klebsiella pneumonia.

Objectives:
This study was designed to investigate the prevalence of iron uptake coding genes among isolates of Klebsiella pneumonia.

Materials and Methods:
A total of 300 isolates of Klebsiella pneumonia including 150 clinical isolates and 150 environmental isolates were selected. Finally, the frequency of iroN, iucD, kfuA,hmuR, and ybt [yHPI] genes were detected by PCR method.

Results:
The frequency of kfuA, iucD, iroN, yHPI in clinical isolates were 33.3%, 16.7%, 24.7%, 15.3%, respectively and these genes among environmental isolates were 20.7%, 6%, 49.3% and 0.7%, respectively. Among the clinical isolates, the most frequency genes were kfuA gene [50 isolates] and after that iroN [37 isolates], iucD [25 isolates] and yHPI [23 isolates], the genes with the most frequency among environmental isolates were iroN gene [74 isolates] and following that kfuA [31 isolates], iucD [9 isolates] and yHPI [1 isolate]. No hmuR positive samples among all clinical or environmental isolates were found.

Conclusion:
The result of this study showed that because of the high frequency of ferric iron system coding gene kfu among clinical isolates, this system might play an important role in the survival of bacteria against its host.
Pengaruh Induksi Benih dengan Natrium Klorida terhadap Pertumbuhan dan Hasil Tiga Kultivar Kedelai (<i>Glycine max</i> L.) pada Cekaman Salinitas
Authors: Prakoso Mohamad Nur Eko Aji , Kurniasih Budiastuti 
Published: May 2020

Penelitian ini bertujuan mempelajari pengaruh induksi benih dengan larutan NaCl terhadap pertumbuhan dan hasil tiga kultivar kedelai dalam kondisi tercekam salin. Penelitian ini dilaksanakan di Rumah Kawat, Fakultas Pertanian, Universitas Gadjah Mada pada bulan Maret-Agustus 2018. Penelitian disusun dalam Rancangan Acak Kelompok Lengkap (RAKL) dengan 2 faktor + 1 non-salin. Faktor pertama yaitu induksi benih dengan NaCl (mM) yang terdiri atas tiga konsentrasi yaitu 0 mM, 40 mM dan 80 mM. Faktor kedua adalah kultivar kedelai yang terdiri dari kultivar Anjasmoro, Dering dan Grobogan. Salinitas tidak mempengaruhi pertumbuhan pada ketiga kultivar, namun hanya pada kultivar Dering yang mengalami penurunan hasil. Dibandingkan tanpa induksi benih, induksi benih pada konsentrasi 80 mM NaCl secara signifikan meningkatkan bobot segar tajuk. Namun demikian, semua konsentrasi induksi benih tidak menunjukkan pengaruh yang signifikan terhadap hasil kedelai yang tercekam salinitas.
TEACHING WRITING NARRATIVE TEXT BY USING COLLABORATIVE LEARNING
Authors: Rizki Indra , Nouvaldi Deyan , Apsari Yanuarti 
Published: May 2020

Writing is an important skill that should be mastered by English learner. This research deals with teaching writing narrative text by using Collaborative Learning Approach (round table technique) and Scientific Approach. The subjects of this research were X RPL 1 as experimental class and X RPL 3 as control class. Both classes consist of 33 students. The objectives of this research are to know wheter or not the difference between students’ writing ability who were taught by using Collaborative Learning. This research employs the quasi experimental design. The instrument of this ressearch are writing test (pre-test and post test), observation, and interview. The data were analyzed by using statistical product and service solution (SPSS) 25 which through the normality and mann whitney process. The findings showed that the calculation result of gain score showed that the significance value was lower than 0.05 (0.0049 < 0.05) which means there is a difference between students who were taught by Collaborative Learning and those who were taught by using Scientific Approach. Keywords: Writing, Narrative, Collaborative Learning, Round Table Technique
PERSON DEIXIS AND SPATIAL DEIXIS OF KING DANGDUT BY RHOMA IRAMA SONGS
Authors: Natalia Yen Yen , Santoso Iman 
Published: May 2020

The aims of this research to find deixis and spatial deixis used of song lyrics from King of Dangdut by Rhoma Irama. Descriptive qualitative method used to collect the data. The classified into type of deixis on the own criteria and the findings that the types of deixis like person deixis and spatial deixis used song lyrics of Rhoma irama. From the result, it can be concluded that person deixis and spatial deixis of finding and discussion is found in all song lyrics, personal deixis is the most being founding 81 words that is the word “Aku, Daku, Ku, Kamu, Mu, and Nya, dominate all songs. The position is the spatial deixis 20 words. It can be seen of the result analysis person deixis and spatial deixis can be many found in the six-song lyrics. Keywords: Person deixis, Spatial deixis, Music
A SOCIOLINGUISTICS ANALYSIS OF ADRESSING TERM USED IN AISYAH: BIARKAN KAMI BERSAUDARA MOVIE
Authors: Syahidawati Neneng Meilinda Nur , Parmawati Aseptiana 
Published: May 2020

The purpose of this research, namely analyzing Aisyah : biarkan kami bersaudara movie to find out the type of addressing term used in this movie. This research uses descriptive qualitative method taken from the dialogue spoken by the characters in Aisyah : biarkan kami bersaudara movie. In this movie five addressing terms are found, namely the addressing term using name, addressing term using kinship name, addressing term using intimacy name, addressing term using respect name, and addressing term Using mockery name. The most commonly used term is addressing term using name.Keywords: Adressing Term, Movie
STUDENTS’ ERROR IN USING SIMPLE PRESENT TENSE
Authors: Siregar Horia , Zuriani Melisa 
Published: May 2020

This research aimed to analyse the errors in using simple present tense. Descriptive qualitataive approach was used in this reserch. The subject of this research was 37 management students of Economic Faculty Muslim Nusantara Al Washliyah University Medan. The data were the sudents’ answer test. This research was analysed by Surface strategy taxonomy proposed by Dulay et al. The results of the research showed that there are four types of students’ errors in using simple present tense. These errors are categorized into omissions, additions, misinformation, and misordering. The most errors made by students is omission with 50,61%,and the lowest is misordering with 2,47%. Keywords: Error Analysis, Simple Present Tense, Types of Error