bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of a standardized tube weaning program in pediatric patients with feeding difficulties after successful repair of their esophageal atresia/tracheoesophageal fistula
Authors: Marinschek Sabine , Pahsini Karoline , Aguiriano-Moser Victor , Russell Marion , Plecko Barbara , Reininghaus Eva Z. , Till Holger , Dunitz-Scheer Marguerite 
Published: May 2020

AbstractChildren born with esophageal atresia (EA) might suffer from significant oral feeding problems which could evolve into tube dependency. The primary aim of the study was to define the outcome of tube weaning in children after successful EA repair and to compare outcomes in children with short gap/TEF (tracheoesophageal fistula) and long-gap EA. Data of 64 children (28 with short-gap EA/TEF with primary anastomosis and 36 with long-gap EA with delayed surgical repair) who participated in a standardized tube weaning program based on the “Graz model of tube weaning” (in/outpatients in an intensive 3-week program, online coaching (Netcoaching) only, or a combined 2-week intensive onsite followed by online treatment “Eating School”) from 2009 to 2019 was evaluated. Sixty-one patients completed the program by transitioning to exclusive oral intake (95.3%). Three children (4.7%) were left partially weaned at the time of discharge. No significant differences could be found between short gap/TEF and long-gap EA group regarding outcomes.Conclusions: The study’s findings support the efficacy of tube weaning based on the published “Graz model of tube weaning” for children born with EA/TEF and indicate the necessity of specialized tube weaning programs for these patients.

What is Known:• Children with esophageal atresia/tracheoesophageal fistula often suffer from feeding problems and tube dependency.• Different tube weaning programs and outcomes have been published, but not specifically for children with EA.

What is New:• Evaluation of a large sample of children referred for tube weaning after EA repair.• Most children with EA can be weaned off their feeding tubes successfully after attending a specialized tube weaning program.
Resistance exercise and breast cancer–related lymphedema—a systematic review update and meta-analysis
Authors: Hasenoehrl Timothy , Palma Stefano , Ramazanova Dariga , Kölbl Heinz , Dorner Thomas E. , Keilani Mohammad , Crevenna Richard 
Published: May 2020

Abstract
Background
The purpose of this systematic review update and meta-analysis was to analyze resistance exercise (RE) intervention trials in breast cancer survivors (BCS) regarding their effect on breast cancer-related lymphedema (BCRL) status and upper and lower extremity strength.

Methods
Systematic literature search was conducted utilizing PubMed, MEDLINE, and Embase databases. Any exercise intervention studies—both randomized controlled and uncontrolled—which assessed the effects of RE on BCRL in BCS in at least one intervention group published between 1966 and 31st January 2020 were included. Included articles were analyzed regarding their level of evidence and their methodological quality using respective tools for randomized and nonrandomized trials of the Cochrane collaboration. Meta-analysis for bioimpedance spectroscopy (BIS) values as well as upper and lower extremity strength was conducted.

Results
Altogether, 29 studies were included in the systematic review. Results of six studies with altogether twelve RE intervention groups could be pooled for meta-analysis of the BCRL. A significant reduction of BCRL after RE was seen in BIS values (95% CI − 1.10 [− 2.19, − 0.01] L-Dex score). Furthermore, strength results of six studies could be pooled and meta-analysis showed significant improvements of muscular strength in the upper and lower extremities (95% CI 8.96 [3.42, 14.51] kg and 95% CI 23.42 [11.95, 34.88] kg, respectively).

Conclusion
RE does not have a systematic negative effect on BCRL and, on the contrary, potentially decreases it.
A theoretical study of chemical bonding and topological and electrostatic properties of the anti-leprosy drug dapsone
Authors: Rajendran Niranjana Devi , Mookan Natarajan , Samuel Israel , Mookan Sarath Babu , Munusamy Govindarajan , Gurudeeban Selvaraj , Kaliamurthi Satyavani 
Published: May 2020

AbstractThe theoretical charge density study for the gas phase of anti-leprosy drug Dapsone has been carried out in the light of the theory of atoms in molecules using density functional theory employing B3LYP(6-311G++(d, p) hybrid functional completed with dispersion corrections. The Hirshfeld surface analysis as well as fingerprint plots has been utilized to visualize and quantify the intermolecular contacts present in the molecule. The topological properties such as electron density and its Laplacian, delocalization index have been elucidated to throw light into the chemical bonding and atomic and molecular details. The electron localization function has been used to visualize and deduce information on the lone pair and the subshells of the Cl atom. The electrostatic potential visualizes the positive and negative electrostatic potential regions which are susceptible to nucleophilic and electrophilic attack. On the whole, this study provides an exact mechanism, interaction, and topological and electrostatic properties of the drug through theoretical insights which all will be a platform for our further investigation of the interaction between dapsone and dihydropteroate synthase (DHPS).
Environmental Inequality and Economic Valuation
Authors: Meya Jasper N. 
Published: May 2020

AbstractI study how the economic value of a heterogeneously distributed environmental public good depends on how the endowment with this good and income are distributed. I find that the effect of environmental inequality on the societal willingness to pay (WTP) for the environmental good is determined both by its substitutability and by the correlation of its provision with income. Specifically, environmental inequality decreases societal WTP for substitutes, but this effect is reversed if the environmental good is a complement or distributed strongly in favour of richer households. Moreover, I show that richer households living in places where environmental good endowment is high increases (decreases) societal WTP if and only if the environmental good is a substitute for (complement to) consumption goods. I propose novel adjustment factors for structural benefit transfer to control for differences in the spatial distribution of environmental goods. Using forest preservation in Poland as an empirical example, I find that societal WTP is up to 4% higher for equal access to forests and up to 8% higher for an equal distribution of both income and access to forests.
Antipsychotic use in dementia: the relationship between neuropsychiatric symptom profiles and adverse outcomes
Authors: Mueller Christoph , John Christeena , Perera Gayan , Aarsland Dag , Ballard Clive , Stewart Robert 
Published: May 2020

AbstractAntipsychotic treatments are associated with safety concerns in people with dementia. The authors aimed to investigate whether risk of adverse outcomes related to antipsychotic prescribing differed according to major neuropsychiatric syndromes—specifically psychosis, agitation, or a combination. A cohort of 10,106 patients with a diagnosis of dementia was assembled from a large dementia care database in South East London. Neuropsychiatric symptoms closest to first dementia diagnosis were determined according to the Health of the Nation Outcome Scales’ mental and behavioural problem scores and the sample was divided into four groups: ‘agitation and psychosis’, ‘agitation, but no psychosis’, ‘psychosis, but no agitation’, and ‘neither psychosis nor agitation’. Antipsychotic prescription in a one-year window around first dementia diagnosis was ascertained as exposure variable through natural language processing from free text. Cox regression models were used to analyse associations of antipsychotic prescription with all-cause and stroke-specific mortality, emergency hospitalisation and hospitalised stroke adjusting for sixteen potential confounders including demographics, cognition, functioning, as well as physical and mental health. Only in the group ‘psychosis, but no agitation’ (n = 579), 30% of whom were prescribed an antipsychotic, a significant antipsychotic-associated increased risk of hospitalised stroke was present after adjustment (adjusted hazard ratio (HR) 2.16; 95% confidence interval (CI) 1.09–4.25). An increased antipsychotic-related all-cause (adjusted HR 1.14; 95% CI 1.04–1.24) and stroke-specific mortality risk (adjusted HR 1.28; 95% CI 1.01–1.63) was detected in the whole sample, but no interaction between the strata and antipsychotic-related mortality. In conclusion, the adverse effects of antipsychotics in dementia are complex. Stroke risk may be highest when used in patients presenting with psychosis without agitation, indicating the need for novel interventions for this group.
Semiempirical identification of nonlinear dynamics of a two-degree-of-freedom real torsion pendulum with a nonuniform planar stick–slip friction and elastic barriers
Authors: Lisowski Bartłomiej , Retiere Clement , Moreno José Pablo Garcia , Olejnik Paweł 
Published: May 2020

AbstractThe purpose of this study is to identify the nonlinear dynamics of the double torsion pendulum with planar friction and elastic barriers. The original experimental stand consists of a disk-shaped body that rotates freely on top of a forced column with a system of barriers limiting the torsional vibrations of the pendulum bodies that create an nonuniform planar rotational friction contact. Two beam springs form soft barriers modeled by Voigt elements that limit the angular displacement of one of the pendulum bodies—the disk, while the second limiting system, made of a much more rigid barrier, limits the movement of the pendulum’s second body. The dynamic behavior of the asymmetrical system of two degrees of freedom with discontinuities is identified with the use of the described strategy, numerical solutions of the derived mathematical model and the Nelder–Mead simplex algorithm. The actual measurement series and numerical solutions show a good similarity of the dynamical reaction of the mechanical system and its virtual analog.
Is there a golden age in publication activity?—an analysis of age-related scholarly performance across all scientific disciplines
Authors: Győrffy Balázs , Csuka Gyöngyi , Herman Péter , Török Ádám 
Published: May 2020

AbstractWe examined whether the publication characteristics of various scientific disciplines exhibit age-related trends. Our analysis was based on two large data sets comprising all major scientific disciplines. Citation data for European Research Council grant holders (ERC,n = 756) were obtained from Google Scholar. Publication data for Hungarian researchers (HUN,n = 2469) were obtained from the Hungarian Scientific Work Archive. The evaluated performance parameters include the number of citations received and the number of high quality first/last author papers published in the last five years. We designated the time between maximum growth and the achieved maximal annual value of total citations as the Golden Age of a researcher. Regarding citation growth, the mean age at the highest growth was 41.75 and 41.53 years for ERC grantees and Hungarian researchers, respectively. Each discipline had different values, with mathematics (38.5 years, ERC) and biology (34.7 years, HUN) having the youngest mean age of highest citation growth and agriculture (45.2 years, ERC) and language sciences (49.9 years, HUN) having the oldest mean age. The maximal growth of publications occurred at 44.5 years, with physics starting first (40.5 years, HUN) and language sciences as last (51.4 years, HUN). Most academic careers require decades to reach their peak and the length of the period of maximum performance varies across disciplines. The most creative time period is rising and is currently in the second half of the forties. Identifying the Golden Age in diverse research careers may be of substantial help in the distribution of grants and tenure positions.
Sophistry about symmetries?
Authors: Martens Niels C. M. , Read James 
Published: May 2020

AbstractA common adage runs that, given a theory manifesting symmetries, the syntax of that theory should be modified in order to construct a new theory, from which symmetry-variant structure of the original theory has been excised. Call this strategy for explicating the underlying ontology of symmetry-related models reduction. Recently, Dewar has proposed an alternative to reduction as a means of articulating the ontology of symmetry-related models—what he calls (external) sophistication, in which the semantics of the original theory is modified, and symmetry-related models of that theory are treated as if they are isomorphic. In this paper, we undertake a critical evaluation of sophistication about symmetries—we find the programme underdeveloped in a number of regards. In addition, we clarify the interplay between sophistication about symmetries, and a separate debate to which Dewar has contributed—viz., that between interpretational versus motivational approaches to symmetry transformations.
Exploring Elimination Kinetics of Four 5-Nitrofuran Derivatives by Microbes Present in Rural and Municipal Activated Sludge
Authors: Pacholak Amanda , Zdarta Agata , Frankowski Robert , Cybulski Zefiryn , Kaczorek Ewa 
Published: May 2020

AbstractThe wastewater treatment plants (WWTPs) are the biggest reservoirs of pharmaceutical residues discharged into the environment. Among many pharmaceuticals, derivatives of 5-nitrofuran, whose cytotoxicity and neurotoxicity have been proved, are widely used. The ability of such compounds to accumulate in water and sediments motivated us to analyze the ability of microbial communities of rural and municipal WWTPs to eliminate nitrofurantoin (NFT), nitrofurazone (NFZ), furaltadone (FTD), and furazolidone (FZD). Metagenomic analysis of microbial communities in rural and municipal activated sludge has provided information about the bacterial biodiversity in the WWTPs. In both samples, the most dominant phylum in terms of abundance was Proteobacteria followed by Bacteroidetes; however, microbial community of the municipal WWTP exhibited greater biodiversity than the one of the rural WWTP. The results of high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) analysis of the samples and elimination kinetic calculations allowed the determination of FZD, FTD, NFT, and NFZ elimination half-time varying from 104 to 327 h and test system first-order half-lives in the examined WWTP samples (from 31 to 231 h). Moreover, a comparison of the effectiveness of the microbials from two treatment plants, a rural one and a municipal one, revealed the poorer performance of the microbial communities from the smaller, rural WWTP in disposal of the analyzed pharmaceuticals, as after 24 days, the rural WWTP community was able to eliminate from 20 to 62% of 5-nitrofuran derivatives, while the municipal consortium removed over 85% of the compounds from the cultures.
Ceramic water filter for point-of-use water treatment in developing countries: Principles, challenges and opportunities
Authors: Yang Haiyan , Xu Shangping , Chitwood Derek E. , Wang Yin 
Published: May 2020

AbstractDrinking water source contamination poses a great threat to human health in developing countries. Point-of-use (POU) water treatment techniques, which improve drinking water quality at the household level, offer an affordable and convenient way to obtain safe drinking water and thus can reduce the outbreaks of waterborne diseases. Ceramic water filters (CWFs), fabricated from locally sourced materials and manufactured by local labor, are one of the most socially acceptable POU water treatment technologies because of their effectiveness, low-cost and ease of use. This review concisely summarizes the critical factors that influence the performance of CWFs, including (1) CWF manufacturing process (raw material selection, firing process, silver impregnation), and (2) source water quality. Then, an in-depth discussion is presented with emphasis on key research efforts to address two major challenges of conventional CWFs, including (1) simultaneous increase of filter flow rate and bacterial removal efficiency, and (2) removal of various concerning pollutants, such as viruses and metal(loid)s. To promote the application of CWFs, future research directions can focus on: (1) investigation of pore size distribution and pore structure to achieve higher flow rates and effective pathogen removal by elucidating pathogen transport in porous ceramic and adjusting manufacture parameters; and (2) exploration of new surface modification approaches with enhanced interaction between a variety of contaminants and ceramic surfaces.
Daytime concentrations of minor and trace elements in atmospheric aerosols at four sampling sites of Dar es Salaam, Tanzania
Authors: Mmari Albert Geoffrey , Hassan Hassan Ali , Bencs László 
Published: May 2020

AbstractTropospheric aerosols (total suspended particulate, TSP) were sampled at four sampling sites of various anthropogenic impact (industrial, commercial, heavy trafficked, and mixed urban influence), located in Dar es Salaam, the commercial capital of Tanzania. Air concentrations of minor and trace elements (Al, As, Br, Ca, Cd, Cl, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, S, Si, Sb, and Zn) in TSP were determined by means of wavelength-dispersive X-ray fluorescence (WDXRF) spectrometry and inductively coupled plasma atomic emission spectrometry (ICP-AES). From these data, the main ionic composition of particulate matter was inferred by means of a species correlation/ratio-derived approach, based on former studies of the region. Enrichment factors, bivariate correlations, diagnostic ratios, and chemical mass closures were calculated utilizing the concentration data of TSP constituents for each site in order to reveal the emission sources. A couple of diagnostic ratios (Ni/Cd, Zn/Cd, Br/Ni, Ni/Sb) were useful for source identification, e.g., motor vehicle exhaust and non-exhaust emissions. Significant increases in concentrations of As, Br, Cr, Cu, Mn, Ni, Pb, and Zn were observed, as compared to results for the city before 2010. Moreover, first-time air levels are reported for Cd and Sb, which are important markers of non-exhaust emissions. Air quality indices and calculations with the AIRQ+ model have foreseen increases in the negative health effects of the sensitive groups of the local population at the study areas, especially those with heavy traffic, industrial, and/or mixed urban influence.
1H, 13C and 15N assignment of the paramagnetic high potential iron–sulfur protein (HiPIP) PioC from Rhodopseudomonas palustris TIE-1
Authors: Trindade Inês B. , Invernici Michele , Cantini Francesca , Louro Ricardo O. , Piccioli Mario 
Published: May 2020

AbstractHigh potential iron–sulfur proteins (HiPIPs) are a class of small proteins (50–100 aa residues), containing a 4Fe–4S iron–sulfur cluster. The 4Fe–4S cluster shuttles between the oxidation states [Fe4S4]3+/2+, with a positive redox potential in the range (500–50 mV) throughout the different known HiPIPs. Both oxidation states are paramagnetic at room temperature. HiPIPs are electron transfer proteins, isolated from photosynthetic bacteria and usually provide electrons to the photosynthetic reaction-center. PioC, the HIPIP isolated from Rhodopseudomonas palustris TIE-1, is the smallest among all known HiPIPs. Despite their small dimensions, an extensive NMR assignment is only available for two of them, because paramagnetism prevents the straightforward assignment of all resonances. We report here the complete NMR assignment of 1H, 13C and 15N signals for the reduced [Fe4S4]2+ state of the protein. A set of double and triple resonance experiments performed with standardized parameters/datasets provided the assignment of about 72% of the residues. The almost complete resonance assignment (99.5% of backbone and ca. 90% of side chain resonances) was achieved by combining the above information with those obtained using a second set of NMR experiments, in which acquisition and processing parameters, as well as pulse sequences design, were optimized to account for the peculiar features of this paramagnetic protein.
Linking aviation security failures to human-mediated error. A review of the related literatures with directions for policy and research
Authors: McFarlane Paul 
Published: May 2020

AbstractGiven the continued growth of air traffic demand and the importance of preventing aviation security failures in this increasingly complex system, this paper offers a review of the relevant literatures relating to the linkages between aviation security failures and human-mediated error. It argues that academics, security professionals and policymakers have given very little consideration to the complexity of these linkages; understanding how human errors can create hidden modes of failure that can be exploited by terrorists and other threat groups. This paper discusses how the literatures in other related fields can be used to explain how human-mediated errors are created and incubated, and how these error types can evolve to become system vulnerabilities and exploitable modes of aviation security failure. The paper concludes by identifying a significant gap in the current theoretical discourse. Implications for actionable policy and research recommendations include taking a fresh approach to proactively mitigating risk; implementing an over-arching risk management strategy which includes analysing data relating to aviation security failures and developing predictive models to detect abnormal and sub-optimal security performance.
External Mindfulness
Authors: Anālayo Bhikkhu 
Published: May 2020

AbstractDescriptions of the formal cultivation of mindfulness in theSatipaṭṭhāna-suttaand its parallels highlight that such practice has “internal” and “external” dimensions. Later traditions reflect a variety of viewpoints on the implications of these dimensions of establishing mindfulness. Perhaps due to the resultant uncertainty, contemporary research on the potential applicability and benefits of mindfulness has so far predominantly focused on the internal aspects. An examination of theSatipaṭṭhāna-suttaand its parallels from the historical viewpoint of their gradual evolution can help to clarify that the chief concern of such external cultivation is directing mindfulness to others.
Enhanced thermoelectric properties of hydrothermally synthesized n-type Se&Lu-codoped Bi2Te3
Authors: Shi Xiaolei , Ai Xin , Zhang Qihao , Lu Xiaofang , Gu Shijia , Su Li , Wang Lianjun , Jiang Wan 
Published: May 2020

AbstractN-type Se&Lu-codoped Bi2Te3nanopowders were prepared by hydrothermal method and sintered by spark plasma sintering technology to form dense samples. By further doping Se element into Lu-doped Bi2Te3samples, the thickness of the nanosheets has the tendency to become thinner. The electrical conductivity of Lu0.1Bi1.9Te3−xSexmaterial is reduced with the increasing Se content due to the reduced carrier concentration, while the Seeback coefficient values are enhanced. The lattice thermal conductivity of the Lu0.1Bi1.9Te3−xSexis greatly reduced due to the introduced point defects and atomic mass fluctuation. Finally, the Lu0.1Bi1.9Te2.7Se0.3sample obtained a maximumZTvalue of 0.85 at 420 K. This study provides a low-cost and simple low-temperature method to mass production of Se&Lu-codoped Bi2Te3with high thermoelectric performance for practical applications.