bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE SOCIAL CONSTRUCTION OF US NAVAL CAPABILITY IN HOLLYWOOD FILMS
Authors: Widjaja Daniel Anugerah 
Published: June 2020

<p>The US Navy has become one of the primary arms of US power projection, deployed worldwide and possessing high mobility. On the other hand, Hollywood cinema has been one of the hallmarks of US cultural soft power. During the time that Hollywood cinema has existed, the US Navy has appeared multiple times within the film art form. However, almost no literature exists that seeks to examine these films as vessels for the social construction of ideas around the US Navy. This research uses interpretive social science and constructivism to explore the themes contained within naval films. It argues that these films help construct an image of a mobile and highly competent navy serving a righteous cause. It also argues the constitutive effects the film has on its audience. </p><div><strong>BAHASA INDONESIA ABSTRAK</strong>: Tersebar di seluruh dunia dan memiliki mobilitas yang sangat tinggi, Angkatan Laut AS adalah salah satu instrumen militer utama yang digunakan untuk mencerminkan kekuatan Amerika Serikat. Karya film Hollywood merupakan salah satu titik unggul kekuasaan lunak (<em>softpower</em>) budaya Amerika Serikat. Angkatan Laut AS banyak tampil dalam karya film Hollywood dari awal produksi perfilman tersebut. Namun, tidak banyak literatur akademik yang menelaah karya film tersebut sebagai sarana konstruksi sosial mengenai citra yang menyangkut Angkatan Laut AS. Penelitian ini menggunakan ilmu sosial interpretatif dan konstruktivisme untuk mengeksplorasi tema-tema yang ada dalam film-film ber-<em>genre </em>angkatan laut. Karya tulis ini juga bertujuan untuk menunjukan bahwa karya-karya tersebut mendukung pencitraan Angkatan Laut AS sebagai kesatuan yang sangat kompeten dan gesit dalam menjalankan tugas dengan nilai moral. Pada akhirnya, penelitian ini berusaha menunjukan efek konstitutif bagi penonton dari film-film tersebut, dan bagaimana hal ini dapat menunjang pencitraan antar-subyektif antara Angkatan Laut dan penonton.</div><p> </p>
Caritas Education: Theory to Practice
Authors: Rossillo Kim , Norman Vivian , Wickman Mary , Winokur Elizabeth 
Published: June 2020

Increasingly complex occupational demands along with varied educational and personal examples of caring, may impact the ability to deeply connect with patients. Literature has identified that nurses and patients have differing perceptions of caring behaviors. Jean Watson's Theory of Human Caring provides a framework for care delivery that focuses on the caring nurse–patient relationship and the experience through the patients' lens.Caring healing relationships are at the core of professional nursing. The purpose of this project was to design and deliver an educational seminar based on Jean Watson's Theory of Human Caring to newly graduated nurses to examine the impact on self-efficacy in caring behaviors.The project participants (N = 56) consisted of a nonprobability convenience sample of newly graduated nurses at a local faith-based community hospital. The educational intervention consisted of experiential learning activities to facilitate translating theory to practice. The study utilized the Caring Efficacy Scale (CES), which is an instrument based on Watson's caring theory and Albert Bandura's self-efficacy theory. Results demonstrated a significant improvement in caring efficacy between the preintervention (M = 5.1, SD = .47), and immediate post intervention (M = 5.5, SD = .38); t (52) = −9.09, p = .000.The knowledge from this study could provide insights for the development of effective teaching strategies to facilitate translating nursing theory to practice. Establishing and developing skills to facilitate nurturing, caring nurse–patient relationships may enhance both the patient and caregiver experience.
Brown adipose tissue activity is modulated in olanzapine-treated young rats by simvastatin
Authors: Liu Xuemei , Feng Xiyu , Deng Chao , Liu Lu , Zeng Yanping , Hu Changhua 
Published: June 2020

Abstract

Background: Prescription of second-generation antipsychotic drugs (SGAs) to childhood/adolescent has exponentially increased in recent years, which was associated with the greater risk of significant weight gain and dyslipidemia. Statin is considered a potential preventive and treatment approach for reducing SGA-induced weight gain and dyslipidemia in schizophrenia patients. However, the effect of statin treatment in children and adolescents with SGA-induced dyslipidemia is not clearly demonstrated. Methods: To investigate the efficacy of statin interventions for reversing SGA-induced dyslipidemia, young Sprague Dawley rats were treated orally with either olanzapine (1.0 mg/kg, t.i.d .), simvastatin (3.0 mg/kg, t.i.d .), olanzapine plus simvastatin (O+S), or vehicle (control) for 5 weeks.Results: Olanzapine treatment increased weight gain, food intake and feeding efficiency compared to the control, while O+S co-treatment significantly reversed body weight gain but without significant effects on food intake. Moreover, olanzapine treatment induced a slight but significant reduction in body temperature, with a decrease in locomotor activity. Fasting plasma glucose, triglycerides (TG), and total cholesterol (TC) levels were markedly elevated in the olanzapine-only group, whereas O+S co-treatment significantly ameliorated these changes. Pronounced activation of lipogenic gene expression in the liver and down-regulated expression of uncoupling protein-1 (UCP1) and peroxisome-proliferator-activated receptor-γ co-activator-1α (PGC-1α) in brown adipose tissue (BAT) was observed in the olanzapine-only group. Interestingly, these protein changes could be reversed by co-treatment with O+B. Conclusions: Simvastatin is effective in ameliorating TC and TG elevated by olanzapine. Modulation of BAT activity by statins could be a partial mechanism in reducing metabolic side effects caused by SGAs in child and adolescent patients.
Tim-3 promotes cell aggressiveness and paclitaxel resistance through the NF-κB /STAT3 signaling pathway in breast cancer
Authors: Cong Yizi , Cui Yuxin , Zhu Shiguang , Cao Jianqiao , Qiao Guangdong , Zou Haidong , Jiang Wenguo , Yu Zhigang 
Published: June 2020

Abstract
Background: T-cell immunoglobulin and mucin-domain containing molecule-3 (Tim-3) has been recognized as a promising target for cancer immunotherapy, but its exact role in breast cancer has not been fully elucidated. Methods: The gene expression level of Tim-3 in breast cancer and its prognostic significance were analysed. In vitro functions and associated mechanisms were then explored through establishing Tim-3 overexpressing breast cancer cells.Results: The gene expression level of Tim-3 was significantly higher (p<0.001) in breast cancer tissue compared to normal tissue following pooled analysis of TCGA database. Tim-3 was a prognosis indicator in breast cancer patients as shown by KM-plotter (RFS: p=0.004; OS: p=0.099). Overexpression of the Tim-3 in Tim-3low breast cancer cells promoted aggressiveness of breast cancer cells including proliferation, migration, invasion, tight junction deterioration and tumour-associated tubal formation. Furthermore, Tim-3 enhanced cellular resistance to paclitaxel. Tim-3 exerted its function by activating the NF-κB/STAT3 signalling pathway, and mediating gene regulation (upregulating CCND1, C-Myc, MMP1, TWIST, VEGF while downregulating E-cadherin). Additionally, Tim-3 downregulated tight junction molecules: ZO-2, ZO-1 and Occludin, which might further facilitate the tumour progression. Conclusions: Tim-3 plays a tumour-promoting role in breast cancer, which suggests targeting Tim-3 may acquire a clinical benefit in antitumor therapy.
Identification and functional analysis of diet-responsive genes in Spodoptera litura (Fabricius)
Authors: Wang Li , Zhao Peng , Luo Junyu , Wang Chunyi , Zhu Xiangzhen , Zhang Lijuan , Ji Jichao , Zhang Kaixin , Li Dongyang , Zhang Shuai , Cui Jinjie 
Published: June 2020

Abstract
Spodoptera litura is one of the most devastating agricultural pests with a wide range of host plants. To study larval performance on different diets and midgut adaptation at transcriptional levels, feeding assay and RNA-Seq experiments were conducted. RNA interference technology was used to explore the detoxification and metabolism of two cytochrome P450 genes. The bioassay data showed that S. litura larvae developed more quickly when fed on cabbage than when fed on soybean, corn and cotton, tannin can inhibit the growth of S. litura . The result of RNA-Seq indicated that S. litura midgut modified gene expression levels to accommodate different diets, and the most differentially expressed genes were detoxification-related and digestion-related genes . Further analysis showed that the glutathione metabolism pathway was the common detoxification pathway in S. litura. The expression of cytochrome P450 genes showed a clear response to different plant hosts, and these differences may play key functions in primary detoxification of secondary metabolites from host plants. Meanwhile, the digestive enzymes of proteinases, lipases, and carbohydrases in midgut showed special responses to different plant hosts. After injection of dsRNA of CYP321A19 and CYP6AB60 , the expression level of target gene were decreased, and the sensitivity of insect to plant allelochemicals increased and the weight increase significantly slowed. In this study, genes involved in detoxification were identified, and the results demonstrate the genes and pathways S. litura utlize to detoxify specific plant-host allelochemicals. These results may also provide a theoretical basis for S. litura management.
Investigation on microstructure and mechanical properties of short-carbon-fiber/Ti3SiC2 composites
Authors: He Guangqi , Guo Rongxiu , Li Meishuan , Yang Yang , Wang Linshan , Qian Yuhai , Zuo Jun , Xu Jingjun , Liu Changsheng 
Published: June 2020

Abstract
In this paper, short-carbon-fibers (Csf) reinforced Ti3SiC2 matrix composites (Csf/Ti3SiC2 , the Csf content was 0, 2, 5 and 10 vol.%) were fabricated by spark-plasma-sintering (SPS) using Ti3SiC2 powders and Csf as starting materials at 1300 ℃. The effects of Csf addition on the phase compositions, microstructures and mechanical properties (including hardness, flexural strength and fracture toughness) of Csf/Ti3SiC2 composites were investigated. The Csf, with a bi-layered transition layers, i.e. TiC and SiC layer, were homogeneously distributed in the as-prepared Csf /Ti3SiC2 composites. With the increase of Csf content, the fracture toughness of Csf/Ti3SiC2 composites increased, but the flexural strength decreased, while the Vickers hardness decreased initially then increased steadily when the Csf content was higher than 2 vol.%. These changed performances could be attributed to the introduction of Csf and the formation of much stronger interfacial phases.
Comparison of initial thin-section CT features in coronavirus disease 2019 pneumonia and other community-acquired pneumonia
Authors: Zhu Qiao , Ren Cui , Wang Xiao Hua 
Published: June 2020

Abstract
Background Coronavirus disease 2019 (COVID-19) pneumonia caused similar symptoms to other community-acquired pneumonia (CAP). It is important to early quarantine suspected patients with COVID-19 pneumonia from patients with other CAP to reduce cross infection. The purpose of the study is to review and compare initial thin-section computed tomography (CT) features in patients with coronavirus disease 2019 (COVID-19) pneumonia and other community-acquired pneumonia (CAP). Methods 24 cases of COVID-19 pneumonia (14 males and 10 females; age range, 14-87 years; mean age, 48.0 years) and 28 cases of CAP caused by other pathogens (13 males and 15 females; age range, 24-85 years; mean age, 49.5 years) were included. Thin-section CT features of the lungs for all patients were retrospectively reviewed by two independent radiologists. Results There were no significant differences for the shape of main lesions, pure ground glass attenuation (GGA), mixed GGA with consolidation, air bronchogram, linear opacities, halo sign/reversed halo sign, cavitation and lymphadenopathy between the group of COVID-19 pneumonia and the group of other CAP. However, the frequency of crazy-paving appearance, vessel dilatation, bilaterally involvement and peripherally distribution were significantly higher in patients with COVID-19 compared with other CAP ( p =0.031, p =0.000, p =0.029 and p =0.009, respectively). Conversely, the frequencies of pure consolidation, tree-in-bud sign and pleural effusion were significantly higher in patients with CAP than in patients with COVID-19 pneumonia ( p =0.002, p =0.000 and p =0.048, respectively). Conclusion There are considerable overlaps in thin-section CT features between COVID-19 pneumonia and other CAP. However, the presence of crazy paving pattern, vessel dilation, bilateral involvement and peripheral distribution contributes to the diagnosis of COVID-19 pneumonia. While the presence of pure consolidation tree-in-bud sign, pleural effusion can be assisting in exclusive the diagnosis of COVID-19 pneumonia.
Colistin Resistance ㏌ Enterobacteriaceae Isolated from Arthropods in Gifu City, Japan
Authors: Odoi Jusitce Opare , Yamamoto Miku , Sugiyama Michiyo , Asai Tetsuo 
Published: June 2020

Abstract
Background

The emergence of antimicrobial-resistant (AMR) bacteria is an important concern for public and livestock health. Arthropods may serve as vectors that disseminate AMR bacteria across different environments. We examined the phenotype and genotype of antimicrobial resistance in Enterobacteriaceae collected from arthropods in Gifu city, Japan.
Results

A total of 186 Enterobacteriaceae from 94 arthropods were obtained and tested for antimicrobial susceptibility. All isolates were susceptible to the antimicrobial agents tested, except for colistin (39 isolates) and kanamycin (one isolate). The aph(3')-Ia gene and amino acid substitutions in the two-component system were responsible for the kanamycin and colistin resistance, respectively.
Conclusion

Overall Enterobacteriaceae isolated from the arthropods were susceptible to most of the antimicrobial agents. However, a high prevalence of colistin resistance was observed in the isolates from the arthropods. We suspect that this was a result of the production of antimicrobial peptides by the arthropods rather than selective pressure or exposure to colistin in the environment. Thus, arthropods maybe a potential reservoir of colistin resistant bacteria. These findings could be beneficial to public and livestock health management.
Climate and Covid-19 - Upgrade and solar radiation influences based on Brazil cases
Authors: Mendonça Francisco , Anjos Max , Collischonn Erika , Murara Pedro , F. Deise Ely , Limberger Leila , Nascimento Lindberg , Cruz Gilson C. F. da , Roseghini Wilson , Andrade Aparecido R. 
Published: June 2020

Abstract
Background

COVID-19 has confirmed to be a pandemic with global and historical dimensions in the beginning of the 21st century. Climatic conditions are one of the environmental factors that influence communicable diseases, including viral diseases. Despite promising scientific advances into understanding the interaction between climate and COVID-19, a question remains: How can climate influence the pandemic of COVID-19?
Methods

It was updated the publications available on the climate and COVID-19 using Scopus, Web of Science, and PubMed database from January 1 to May 20, 2020. Statistical analysis, such normality and multicollinearity tests were performed between number of COVID-19 cases and climato-meteorological parameters (temperature, relative humidity, dew point temperature, atmosphere pressure, wind speed, wind gust, rainfall, and solar radiation, nebulosity and insolation ratio) in six Brazilian cities.
Results

This review reveals that temperature, relative humidity and absolute humidity alone do not able to explain the exponential number of COVID-19 cases. Most studies showed the SARS-CoV-2 satisfactorily can survive in a large range of temperature and humidity in temperature and tropical- humidity climates. Analyzing other meteorological parameter, insolation ratio that is related to the solar radiation and nebulosity, the results and in accordance with other studies suggest the transmission and contagion by SARS-CoV-2 seem to have been enhanced under from medium to low direct solar radiation and covered skies.
Conclusions

This study showed that the inclusion of other climatic variables, in addition to temperature and humidity, should guide future ecological models on the relationship between climate and COVID-19, especially the insolation ratio influences on the viral transmission in six Brazilian cities. Our findings may support public policies and coordinated actions to reduce and control of COVID-19.
Changes in Local Bone Mineral Density in Patients With Rupture of the Anterior Cruciate Ligament and Its Guiding Significance for Treatment
Authors: Liu Hao , Gu Sanjun , Liu Jun , Wu Yongwei , Rui Yongjun 
Published: June 2020

Abstract
Background:It is recognized that there are many factors that affect the outcomes of anterior cruciate ligament(ACL) reconstruction. However, there were few studies on the effect of local bone conditions on the reconstruction of the ACL. This study aimed to summarize the changes in local bone mineral density (BMD) of the knee after rupture of the ACL and to guide the treatment. Methods: Eighty patients with ACL rupture treated in our department from January 2017 to April 2019 were routinely measured for local bone mineral density before surgery, and according to the bone mineral density, the appropriate method of ligament reconstruction and fixation under arthroscopy was selected: if the local bone mineral density of the affected knee was not significantly lower than that of the healthy side, squeeze fixation was used, and suspension fixation was used when the local bone mineral density of the affected knee was lower than that of the healthy knee. The conditions of tunnel cutting or screw splitting and tunnel enlargement or screw pull-out were observed during the operation, and the fixation mode was adjusted in time according to the situation. The function of the knee joint was evaluated regularly by physical examination, imaging data, the IKDC scale and the Lysholm score table after the operation. Results:A total of 80 patients with unilateral ACL rupture were included in this group. There were 44 males and 36 females. Sixty-eight patients had decreased bone mineral density in the affected knee. The bone mineral density of patients with a history of more than 3 months was lower than that of patients with a history of less than 3 months. Tunnel enlargement and screw pull-out occurred in 2 patients, screw splitting occurred in 1 patient, and no adverse conditions occurred in the rest of the patients. In 3 patients, the fixation mode was adjusted in time during the operation. The patients were followed for 12 months (mean 20.65±5.12 months). The IKDC score increased from 43.07±2.66 before the operation to 89.17±3.28 at the final follow-up, and the Lysholm score increased from 43.49±2.38 to 89.67±2.97. Conclusions:The measurement of local bone mineral density before surgery is of guiding significance for the selection of reconstruction and fixation of the ACL. It is recommended that patients undergo surgical reconstruction within 3 months after injury. When the bone mineral density of the affected knee decreases significantly to at least 70% lower than that of the healthy side, suspension fixation is recommended and the brace fixation time is prolonged.
An Extended Cox Prognostic Model of ER/PR+ and HER2− Breast Cancer Patients
Authors: XIE YIQUN , CUI WENTING , LIU YANG , LI XIZHOU 
Published: June 2020

Abstract
Background: The purpose of this study was to explore a new ER/PR+ and HER2− breast cancer prognostic model called the extended Cox prognostic model by us for determining the cut-off values for multiple continuous prognostic factors and their interaction via the new modeling idea and variable selection method. Methods: A total of 335 patients with ER/PR+, HER2- breast cancer were enrolled for the final analysis. The primary endpoint was breast cancer-specific mortality (BCSM). The prognostic factors (histological grade, histological type, stage, T, N, lymphovascular invasion, P53, Ki67, ER, PR, age) were included in this study. The four continuous valuables (Ki67, ER, PR, age) were partitioned into a series of binary variables which all were fitted in the multivariate Cox analysis. A smoothly clipped absolute deviation (SCAD) variable selection method was used. Model performance was expressed in discrimination and calibration. Results: We developed an extended Cox model with a time threshold at 164 weeks (more than 3 years) post-operation. We found that the cut-off values for PR, Ki67 and age were 20%, 60% and 41-55 years respectively. There was interaction between age and PR for the patients with age≥41years and PR≥20% after 164 weeks post-operation. The patients with age≥41years and PR≥20% after 164 weeks post-operation had relatively higher mortality than before 164 weeks postoperatively. Conclusions: Our study would offer the guidance in the prognosis for the patients with ER/PR+ and HER2− breast cancer in China. The new idea would be one of ideas for modeling and determining the cut-off values of prognostic factors in future.
Association between urban green space and the risk of Alzheimer's disease: A longitudinal study
Authors: Cho Yoosun , Choi Seulggie , Seo Sumin , Lee Gyeongsil , Park Sang Min 
Published: June 2020

Abstract
BackgroundsAlthough studies have demonstrated the beneficial effects of green spaces on general well being, the benefits of urban green spaces on Alzheimer’s disease (AD) are still unclear. In this retrospective cohort study, we sought to ascertain the connection between the presence of green spaces in urban environments and risk of AD.MethodsThe study sample comprised 294,983 participants, aged 40–74 years, and was derived from the Korean National Health Insurance Service National Sample Cohort. We used data of area (m2) and amount of artificial parks in 2005, provided by the Ministry of Land, Infrastructure and Transport. Starting from 2009, after removing those who received a dementia diagnosis within 1–3 years of gathering the index data, participants received follow-up AD testing. The Cox proportional-hazards model was utilized to establish the adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) of AD risk, based on the amount of urban green space area.ResultsCompared to the quartile with the least amount of green space, participants in the highest urban space quartile had a reduced risk of receiving an AD diagnosis (aHR 0.84, 95% CI 0.72–0.99). The mediating effect of green space presence on AD was stronger among those in higher household income brackets (aHR 0.80, 95% CI 0.65–0.99), with more comorbidities (aHR 0.78, 95% CI 0.64–0.96), and without disabilities (aHR 0.82, 95% CI 0.69–0.97).ConclusionsLiving in urban areas with increased green space coverage may ultimately result in a lower risk of being diagnosed with AD. Urban planning strategies capable of boosting the total coverage of urban green space may assist in reducing AD risk.