bluuebunny/crossref_metadata_2025_split huggingface dataset:
Construction of Hierarchical Nanotubes Assembled from Ultrathin V3S4@C Nanosheets towards Alkali‐Ion Batteries with Ion‐Dependent Electrochemical Mechanisms
Authors: Liu Yang , Sun Zehang , Sun Xuan , Lin Yue , Tan Ke , Sun Jinfeng , Liang Longwei , Hou Linrui , Yuan Changzhou 
Published: December 2019

AbstractUltrathin core–shell V3S4@C nanosheets assembled into hierarchical nanotubes (V3S4@C NS‐HNTs) are synthesized by a self‐template strategy and evaluated as general anodes for alkali‐ion batteries. Structural/physicochemical characterizations and DFT calculations bring insights into the intrinsic relationship between crystal structures and electrochemical mechanisms of the V3S4@C NS‐HNTs electrode. The V3S4@C NS‐HNTs are endowed with strong structural rigidness owing to the layered VS2 subunits and interlayer occupied V atoms, and efficient alkali‐ion adsorption/diffusion thanks to the electroactive V3S4‐C interfaces. The resulting V3S4@C NS‐HNTs anode exhibit distinct alkali‐ion‐dependent charge storage mechanisms and exceptional long‐durability cyclic performance in storage of K+, benefiting from synergistic contributions of pseudocapacitive and reversible intercalation/de‐intercalation behaviors superior to those of the conversion‐reaction‐based Li+‐/Na+‐storage counterparts.
Photoinduced Mo−CN Bond Breakage in Octacyanomolybdate Leading to Spin Triplet Trapping
Authors: Qi Xinghui , Pillet Sébastien , de Graaf Coen , Magott Michał , Bendeif El‐Eulmi , Guionneau Philippe , Rouzières Mathieu , Marvaud Valérie , Stefańczyk Olaf , Pinkowicz Dawid , Mathonière Corine 
Published: December 2019

AbstractThe photoinduced properties of the octacoordinated complex K4MoIV(CN)8⋅2 H2O were studied by theoretical calculations, crystallography, and optical and magnetic measurements. The crystal structure recorded at 10 K after blue light irradiation reveals an heptacoordinated Mo(CN)7 species originating from the light‐induced cleavage of one Mo−CN bond, concomitant with the photoinduced formation of a paramagnetic signal. When this complex is heated to 70 K, it returns to its original diamagnetic ground state, demonstrating full reversibility. The photomagnetic properties show a partial conversion into a triplet state possessing significant magnetic anisotropy, which is in agreement with theoretical studies. Inspired by these results, we isolated the new compound [K(crypt‐222)]3[MoIV(CN)7]⋅3 CH3CN using a photochemical pathway, confirming that photodissociation leads to a stable heptacyanomolybdate(IV) species in solution.
Two Four‐Coordinate and Seven‐Coordinate CoII Complexes Based on the Bidentate Ligand 1, 8‐Naphthyridine Showing Slow Magnetic Relaxation Behavior
Authors: Huang Xing‐Cai , Xu Rui , Chen Yong‐Zhi , Zhang Yi‐Quan , Shao Dong 
Published: December 2019

AbstractFor a long time, the cobalt(II) complex ([Co(napy)4](ClO4)2) (napy=1, 8‐naphthyridine) has been considered as an eight‐coordinate complex without any structural proof. After careful considerations, two complexes [Co(napy)2Cl2] (1) and [Co(napy)4](ClO4)2 (2) based on the bidentate ligand napy were synthesized and structurally characterized. X‐ray single‐crystal structural determination showed that the cobalt(II) center in [Co(napy)2Cl2] (1) is four‐coordinate with a tetrahedral geometry (Td), while [Co(napy)4](ClO4)2 (2) is seven‐coordinate rather than eight‐coordinate with a capped trigonal prism geometry (C2v). Direct‐current (dc) magnetic data revealed that complexes 1 and 2 possess positive zero‐field splitting (ZFS) parameters of 11.08 and 25.30 cm−1, respectively, with easy‐plane magnetic anisotropy. Alternating current(ac) susceptibility measurements revealed that both complexes showed slow magnetic relaxation behaviour. Theoretical calculations demonstrated that the presence of easy‐plane magnetic anisotropy (D>0) for complexes 1 and 2 is in agreement with the experimental data. Furthermore, these results pave the way to obtain four‐coordinate and seven‐coordinate cobalt(II) single‐ion magnets (SIMs) by using a bidentate ligand.
Furan‐Derived Chiral Bicycloaziridino Lactone Synthon: Collective Syntheses of Oseltamivir Phosphate (Tamiflu), (S)‐Pipecolic acid and its 3‐Hydroxy Derivatives
Authors: Chavan Subhash P. , Kadam Appasaheb L. , Shinde Shrikrishna S. , Gonnade Rajesh G. 
Published: December 2019

AbstractA unified synthetic strategy for oseltamivir phosphate (tamiflu), (S)‐pipecolic acid, and its 3‐hydroxy derivatives from furan derived common chiral bicycloaziridino lactone synthon is described here. Key features are the short (4‐steps), enantiopure, and decagram‐scale synthesis of common chiral synthon from furan and its first‐ever application in the total synthesis of biologically active compounds by taking the advantages of high functionalization ability of chiral synthon.
Exploring Anxiety at Home, School, and in the Community Through Self‐Report From Children on the Autism Spectrum
Authors: Adams Dawn , Simpson Kate , Keen Deb 
Published: December 2019

Research investigating anxiety in children on the autism spectrum usually reports caregiver rather than self‐report perspectives. This study aimed to document children's own descriptions of their anxiety symptomatology by combining profiles on a standardized autism‐specific self‐report measure of anxiety (ASC‐ASD‐C) with the answers from closed‐ and open‐answer questions about anxiety across home, school, and community settings. Across the sample of 113 children on the spectrum aged 6–14 years, the two most frequently endorsed items on the ASC‐ASD‐C were from the Uncertainty and Performance Anxiety subscales, and the least endorsed were both from the Anxious Arousal subscale. Almost all (96.5%) of the children on the spectrum reported experiencing anxiety in at least one setting, with 40.7% reporting anxiety in all three contexts (home, school, and community). Approximately half of the sample felt their anxiety goes unrecognized by others at school and almost 60% felt it was unrecognized by others when out in the community. The proportion of children reporting having someone to help reduce their anxiety differed across home (86%), school (76%), and community (45%) settings. This highlights the importance of understanding anxiety and its impact, not only within the context of autism but also for each particular child. Autism Res 2020, 13: 603–614. © 2019 International Society for Autism Research, Wiley Periodicals, Inc.Lay summaryThere has been a lot of research focusing on anxiety and autism, but most of it has used parent reports, rather than asking the child themselves. This study summarizes data from 113 children on the autism spectrum, aged 6–14 years. It reports the symptoms of anxiety that these children most and least commonly experience. The results suggest only 40–50% of children feel that others are able to recognize their anxiety at school and when out in the community, suggesting that more training is needed to help adults in these settings to recognize and support anxiety.
Measuring the effects on learning performance and engagement with a gamified social platform in an MSc program
Authors: Garcia‐Cabot Antonio , Garcia‐Lopez Eva , Caro‐Alvaro Sergio , Gutierrez‐Martinez Jose‐Maria , de‐Marcos Luis 
Published: December 2019

AbstractNew generations of students are highly involved with technology. Therefore, while coming to traditional classrooms, it is required to call for different forms of teaching that are more motivating and engaging for them. One approach to this problem is combining games and education. Gamification could be defined as the use of game design elements in non‐game contexts. The research gap in the literature could be found in requiring more experimental studies assessing if gamification can improve learning outcomes. To this end, this paper further contributes to determining if a gamified social e‐learning platform can improve the learning performance and engagement of MSc students. The developed platform combined submission of activities with points, achievements, leaderboards, and rewards (with a virtual store) and social elements such as friends, forums, Q&A, blogs, and microblogging. Results show that, indeed, social gamification is a suitable technique to improve the learning outcome of students, at least for those skills related to programming, providing more communication skills and producing more engagement and motivation while using the platform.
Changing trends in cancer incidence of upper aerodigestive tract and stomach in Japanese alcohol‐dependent men (1993‐2018)
Authors: Yokoyama Akira , Omori Tai , Yokoyama Tetsuji 
Published: December 2019

AbstractBackgroundEsophageal squamous cell carcinoma (ESCC), head and neck SCC (HNSCC), and gastric adenocarcinoma (GA) are frequently detected at an early stage using endoscopic screening in Japanese alcohol‐dependent men.MethodsWe performed endoscopic screening with esophageal iodine staining and oropharyngolaryngeal inspection in 7582 Japanese alcohol‐dependent men (40‐79 years) during 1993‐2018, and retrospectively investigated their initial screening results.ResultsThe 2008‐2018 screening showed lower detection rates for ESCC (2.6% vs 4.0%, P = .0009) and GA (0.5% vs 1.4%, P < .0001) for all age brackets, compared with the 1993‐2007 screening. The HNSCC detection rate did not change (1.0% vs 1.1%). Multiple logistic regression analyses showed that the 2008‐2018 screening had a reduced OR (95% CI) for ESCC (0.34 [0.25‐0.47]) and GA (0.19 [0.10‐0.35]), compared with the 1993–2007 screening. The reduction in H pylori infection is probably the main reason for the decrease in GA detection over time. Declining trends in pack‐years and gastric atrophy and increasing trends in age and body mass index (BMI) were found over time. The presence of advanced gastric atrophy increased the risk for ESCC as well as GA. The inactive heterozygous aldehyde dehydrogenase‐2*1/*2 genotype was a strong risk factor for ESCC, HNSCC, and GA. Fewer pack‐years and a larger BMI decreased the ESCC risk. However, these confounders cannot fully explain why the incidence of ESCC has decreased markedly over the recent decade.ConclusionsThe detection rates of ESCC and GA have markedly decreased during the past decade in the alcohol‐dependent population. The enigmatic declining trend of ESCC warrants research on this topic.
Four New Diterpenoid Alkaloids from The Roots of Aconitum coreanum
Authors: Xu Jin‐Bu , Luo Yan‐Yan , Huang Shuai , Gao Feng , Zhou Xian‐Li 
Published: December 2019

AbstractFour new hetisine‐type C20‐diterpenoid alkaloids, named as coreanines A–D (1–4), were isolated from the roots of Aconitum coreanum, together with thirteen known alkaloids (5–17). Their structures were elucidated by extensive spectroscopic methods including IR, HR‐ESI‐MS and NMR techniques. All the isolated compounds were screened for the acetylcholinesterase (AChE) inhibitory effects, and none of them showed considerable inhibitory activity.
Hexagonal Molybdenum Trioxide (h‐MoO3) as an Electrode Material for Rechargeable Aqueous Aluminum‐Ion Batteries
Authors: Joseph Jickson , O'Mullane Anthony P. , Ostrikov Kostya (Ken) 
Published: December 2019

AbstractAqueous aluminum‐ion batteries are at an early development stage and there is a need to discover new electrode materials for the fabrication of high energy density devices. To address this issue, we investigate MoO3 nanowires as a possible electrode material for use in rechargeable Al‐ion batteries that can operate in aqueous conditions. We present a hexagonal structure of MoO3 microrods as an Al‐ion intercalation host material and show its first‐time use as a potential electrode for an aqueous Al‐ion battery system. This yields a discharge capacity of approximately 300 mAh g−1 for 150 cycles and around 90 % retention after 400 cycles at a current density of 3 A g−1. The utilization of this type of material and aqueous electrolytes guarantees both safety during operation and simple recycling of spent batteries.
Lack of Effect of Rezafungin on QT/QTc Interval in Healthy Subjects
Authors: Flanagan Shawn , Goodman Daniel B. , Jandourek Alena , O'Reilly Terry , Sandison Taylor 
Published: December 2019

AbstractRezafungin is a new echinocandin in development for treatment of candidemia and invasive candidiasis, and for prophylaxis of invasive fungal infections. Rezafungin is the first echinocandin to undergo definitive QT/QTc study. This phase 1, single‐center, randomized, double‐blind trial was conducted to assess effects of intravenous rezafungin vs intravenous placebo (with moxifloxacin as positive control) on the QT interval of the electrocardiogram, corrected for heart rate by Fridericia's formula (QTcF), in healthy adults. Therapeutic (600 mg) and supratherapeutic (1400 mg) rezafungin doses were selected to achieve exposures 2.5‐fold higher than produced by the highest dose used in a phase 2 trial (400 mg once weekly). The primary end point was change in QTcF from baseline (ΔQTcF) as a function of plasma concentration, assessed by comparing upper bounds of the 2‐sided 90% confidence interval. The estimated mean ΔΔQTcF at the mean plasma concentrations for the rezafungin doses had upper bounds <10 milliseconds, within the upper bound of the 2‐sided 90% confidence interval. Intravenous rezafungin up to 1400 mg in a single dose did not prolong QT interval and had no apparent effect on repolarization or QRS duration. Electrocardiogram results showed no clinically significant effects of concern. These findings support the continued development of rezafungin.
The Composite of CuO/Diatomaceous Shale Prepared by Hydrothermal Method and Their Photocatalytic Properties
Authors: Wang Ziyi , Cao Binhua , Wang Zhijun , Chen Qiao , Wang Yongqian 
Published: December 2019

AbstractPhotocatalytic degradation is a new wastewater treatment technology, in which copper oxide (CuO) is a common photocatalyst. Herein, diatomaceous shale is used to load nanoscale CuO, which can, on the one hand, improve the photocatalytic performance, and on the other hand, reduce the cost of catalyst preparation. Furthermore, the morphology, crystal structures, and optical properties of the composite of CuO/diatomaceous shale are studied by scanning electron microscopy, X‐ray diffraction, UV–vis spectrophotometer, energy‐dispersive spectroscopy, and photoluminescence spectroscopy. Through the study of different experimental conditions, the reusability test demonstrates that the morphology and distribution status of CuO nanostructures are controllable. In addition, a group of composite catalysts prepared under the best technological conditions is selected to conduct the actual sewage degradation experiment, and the results show that the prepared composite of CuO/diatomaceous shale has a good degradation effect on sewage. These findings provide an insight into the design and synthesis of new CuO‐based composites to effectively improve their photocatalytic performance.
Properties of Novel Polyesters Made from Renewable 1,4‐Pentanediol
Authors: Stadler Bernhard M. , Brandt Adrian , Kux Alexander , Beck Horst , de Vries Johannes G. 
Published: December 2019

AbstractNovel polyester polyols were prepared in high yields from biobased 1,4‐pentanediol catalyzed by non‐toxic phosphoric acid without using a solvent. These oligomers are terminated with hydroxyl groups and have low residual acid content, making them suitable for use in adhesives by polyurethane formation. The thermal behavior of the polyols was studied by differential scanning calorimetry, and tensile testing was performed on the derived polyurethanes. The results were compared with those of polyurethanes obtained with fossil‐based 1,4‐butanediol polyester polyols. Surprisingly, it was found that a crystalline polyester was obtained when aliphatic long‐chain diacids (>C12) were used as the diacid building block. The low melting point of the C12 diacid‐based material allows the development of biobased shape‐memory polymers with very low switching temperatures (<0 °C), an effect that has not yet been reported for a material based on a simple binary polyester. This might find application as thermosensitive adhesives in the packaging of temperature‐sensitive goods such as pharmaceuticals. Furthermore, these results indicate that, although 1,4‐pentanediol cannot be regarded as a direct substitute for 1,4‐butanediol, its novel structure expands the toolbox of the adhesives, coatings, or sealants formulators.
Highly differentiated follicular carcinoma of ovary: Use of imprint cytology at intraoperative consultation
Authors: Dobi Alice , Kim Sun A. , Zhang Ming , Iames Edward , Lamzabi Ihab 
Published: December 2019

AbstractHighly differentiated follicular carcinoma of ovary (HDFCO) is a rare entity known to arise in struma ovarii. Clinical presentation and radiological features mimic other cystic ovarian neoplasm. Thus, intraoperative diagnosis of this entity can be challenging. We hereby report a HDFCO case of a 52‐year‐old woman, who presented with significant abdominal bloating for 3 months. Imaging showed a 11.7 cm left adnexal‐mixed cystic and solid mass, adhering to the bowel with ascites. The mass was examined intraoperatively and showed multilocular cysts filled with straw or red brown‐colored gelatinous fluid. Microscopically, the tumor consisted of small and large follicles with proteinous material and bland‐looking cuboidal cells, suspicious for struma ovarii or granulosa cell tumor with extensive cystic changes, while imprint cytology slides showed watery colloid with cracking artifact favoring the former. However, the adherence to the bowel suggested HDFCO, and prompted surgical staging. The histology of the ovarian mass in the permanent section resembled goiterous thyroid tissue with invasion of endocervical stroma, uterine wall and colonic serosa, and presence of tumor nodules in omentum leading to the diagnosis of HDFCO. Due to striking resemblance of HDFCO to benign thyroid goiter, searching for invasive and metastatic foci is crucial for correct diagnosis. In addition, intraoperative imprint cytology revealing colloid with cracking artifact is helpful for differentiating struma ovarii and/or HDFCO from other ovarian lesions.
Interplay between morphogen‐directed positional information systems and physiological signaling
Authors: Huizar Francisco , Soundarrajan Dharsan , Paravitorghabeh Ramezan , Zartman Jeremiah 
Published: December 2019

AbstractThe development of an organism from an undifferentiated single cell into a spatially complex structure requires spatial patterning of cell fates across tissues. Positional information, proposed by Lewis Wolpert in 1969, has led to the characterization of many components involved in regulating morphogen signaling activity. However, how morphogen gradients are established, maintained, and interpreted by cells still is not fully understood. Quantitative and systems‐based approaches are increasingly needed to define general biological design rules that govern positional information systems in developing organisms. This short review highlights a selective set of studies that have investigated the roles of physiological signaling in modulating and mediating morphogen‐based pattern formation. Similarities between neural transmission and morphogen‐based pattern formation mechanisms suggest underlying shared principles of active cell‐based communication. Within larger tissues, neural networks provide directed information, via physiological signaling, that supplements positional information through diffusion. Further, mounting evidence demonstrates that physiological signaling plays a role in ensuring robustness of morphogen‐based signaling. We conclude by highlighting several outstanding questions regarding the role of physiological signaling in morphogen‐based pattern formation. Elucidating how physiological signaling impacts positional information is critical for understanding the close coupling of developmental and cellular processes in the context of development, disease, and regeneration.
Breeding habitat and nest‐site selection by an obligatory “nest‐cleptoparasite”, the Amur FalconFalco amurensis
Authors: Frommhold Martin , Heim Arend , Barabanov Mikhail , Maier Franziska , Mühle Ralf‐Udo , Smirenski Sergei M. , Heim Wieland 
Published: December 2019

AbstractThe selection of a nest site is crucial for successful reproduction of birds. Animals which re‐use or occupy nest sites constructed by other species often have limited choice. Little is known about the criteria of nest‐stealing species to choose suitable nesting sites and habitats. Here, we analyze breeding‐site selection of an obligatory “nest‐cleptoparasite”, the Amur FalconFalco amurensis. We collected data on nest sites at Muraviovka Park in the Russian Far East, where the species breeds exclusively in nests of the Eurasian MagpiePica pica. We sampled 117 Eurasian Magpie nests, 38 of which were occupied by Amur Falcons. Nest‐specific variables were assessed, and a recently developed habitat classification map was used to derive landscape metrics. We found that Amur Falcons chose a wide range of nesting sites, but significantly preferred nests with a domed roof. Breeding pairs of Eurasian HobbyFalco subbuteoand Eurasian Magpie were often found to breed near the nest in about the same distance as neighboring Amur Falcon pairs. Additionally, the occurrence of the species was positively associated with bare soil cover, forest cover, and shrub patches within their home range and negatively with the distance to wetlands. Areas of wetlands and fallow land might be used for foraging since Amur Falcons mostly depend on an insect diet. Additionally, we found that rarely burned habitats were preferred. Overall, the effect of landscape variables on the choice of actual nest sites appeared to be rather small. We used different classification methods to predict the probability of occurrence, of which theRandom forestmethod showed the highest accuracy. The areas determined as suitable habitat showed a high concordance with the actual nest locations. We conclude that Amur Falcons prefer to occupy newly built (domed) nests to ensure high nest quality, as well as nests surrounded by available feeding habitats.