bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of iPBS markers to study the genetic diversity of known stock grape varieties
Authors: Savenkova D. S. , Mindiarova V. O. , Filippova Yu. O. , Volkova S. A. , Мilovanov A. V. , Troshin L. P. 
Published: November 2020

The expansion of viticulture in the world is accompanied by the spread of diseases and plant pests. Phylloxera is one of those organisms causing enormous damage to the world’s viticulture. The discovery of the possibility of grafting varieties on stock has led to the development of the breeding of stock originating from North America. Currently, the active use of different types of molecular markers for the identification and study of the genetic diversity of grapes allows to more accurately and efficiently study the biological peculiarities and genetics of plants. Obtaining good reproducibility of the analysis results and revealing the polymorphism between varieties and clones when using different types of markers, you can further use this knowledge for breeding in the selection of crossed pairs. The aim of the study in the present article was to study the common stock grape varieties - hybrids of American species. The article presents a study of the five most famous stock grape varieties: Kober 5BB and 420-A, Paulsen 1103, 101-14 and Richter 57 to identify genetic relationships and polymorphism between samples, based on the use of IRAP and iPBS primers. We used thirteen selected DNA markers that generated a total of 308 polymorphic DNA bands with 54.95 % polymorphism. The effectiveness of iPBS markers was comparable or even more effective than the markers based on retrotransposons. As a result of research, differences and commonality between stocks were clearly demonstrated by both cluster analysis and PCoA analysis.
Influence of the component composition of nutrient media upon the introduction into the culture in vitro of explants of Prikubanskoe and Kubanskoe Bagryanoe apple varieties
Authors: Lobodina E. V. , Suprun I. I. , Avakimyan A. O. , Al-Nakib E. A. 
Published: November 2020

The work reflects the aspects of introducing two varieties of apple trees into the culture in vitro: Prikubanskoe and Kubanskoe Bagryanoe. The aims of study included testing a new disinfection protocol that accurately regulates the content of active chlorine in the disinfecting solution, as well as studying the regenerative ability of explants of apple trees of the Prikubanskoe and Kubanskoe Bagryanoe varieties on different culture medium: Murashige and Skoog (MS) ¼ NH4 NO3 , and Kvorin-Lepuavra (QL). The disinfection protocol used made it possible to obtain an insignificant level of explant contamination with fungal infection in passage zero, which indicates the effectiveness of the tested extraction protocol. The contamination of explants in passage zero by fungal infection was insignificant, which indicates the high efficiency of the sterilizing agent. The level of bacterial infection is higher in the Kubanskoe Bagryanoe variety (21.3 % of the total amount of explants). The influence of the component composition of nutrient media on the primary growth of apple micro-shoots was revealed. The following results were obtained: the yield of viable explants of the Prikubanskoe variety grown on nutrient medium MS ¼ NH4 NO3 was 44,4 %, which is 16,4 % higher than explants grown on QL medium (28 %). Explants of the Kuba nskoe bagryanoe variety, in turn, have a yield of vital microplants grown on MS ¼ NH4 NO3 16.7 %, which is 30.4 % lower than explants grown on QL medium (47.1 %). The combined effect of the genotype and the composition of the nutrient medium on the development of explants was statistically significant for the studied parameters. The share of the cumulative effect of factors of the variety x medium is 74.93 %, the influence of the genotype is 20.72 %. The data obtained indicate the variety specificity of the nutrient medium during clonal micropropagation of these apple varieties.
An Analysis of Management Accounting System Development from the Structuration Theory Viewpoint
Authors: Chan Anthony Moung Yin , Lo Paul , Ng Kong 
Published: November 2020

Our study covered the development and evolution of the management accounting system of a subsidiary company in a group. Our study was a longitudinal one starting from the incorporation of the company. We divided this period into five stages according to the major events happened, namely the formation of the company, the invoicing crisis, the conflict with parent company, the conflict with fellow subsidiaries, and the influence of the chief executive.
In our analysis we applied the three dimensions of structure in the theory of structuration (i.e., signification, legitimation and domination). The structuration theory explained the emergence of certain phenomena and events that were not explained by traditional accounting theories. Many events in our study validated the core ideas of the structuration theory which composes of the concepts of structure, system and duality of structure. The phenomena suggested that structure was both the medium and outcome of the conduct it recursively organized. Other features of the theory, such as the dialectic of control and system contradiction, were also applicable
The Variation of Pulp Canal Configuration in Mandibular Posterior Teeth Using Cone Beam Computed Tomography in Indonesia Subpopulation Mongoloid Race
Authors: Boel Trelia , Kartika Dewi , Dennis  
Published: November 2020

It is important to understand pulp canal configuration to have a successful endodontic treatment. Cone Beam Computed Tomography (CBCT) radiography is able to assess the pulp canal configuration, especially on the lingual/palatal, compared to the periapical radiography. The objective of the research is to know the prevalence pulp canal configuration of mandibular molar teeth in Indonesia subpopulation Mongoloid race using CBCT radiography. This research is a descriptive survey with a cross-sectional approach, using 38 CBCT radiographs from the patients undergoing dental treatments in hospitals in Medan. The subjects were selected based on research criteria; then their CBCT radiographs were interpreted and analyzed. The result shows the existence of mandibular mesial root type 2-1 (28.94%), 1-2-1 (5.26%), 2-2 (55.26%), 2-1-2-1 (2.64%), 3-2 (5.26%), 3-1 (2.64%), distal root type 1-1 (36.84%), 2-1 (23.68%), 1-2-1 (15.79%), 1-2 (2.63%), 2-2 (13.17%), 2-1-2-1 (5.26%), 1-3-1 (2.63%). The distolingual root of mandibular first molars consisted of type 1-1 (100%). Mesial root of mandibular second molars of type 1-1 (2.63%), 2-1 (50%), 1-2-1 (5.26%), 2-2 (36.85%), 2-1-2-1 (2.63%), 1-2-1-2 (2.63%), distal root type 1-1 (57.89%), 2-1 (15.79%), 1-2-1 (13.16%), 2-2 (10.53%), 2-1-2 (2.63%). This variation of the pulp canal can be influenced by the shape of roots. A flat root usually contains pulp canal configuration type II – VIII Vertucci, similarly to mandibular molar mesial canals. As a summary, there is a variation of pulp canal configuration in mandibular first and second molars on Indonesian Mongoloid race, as seen from the CBCT radiographs.
Resenha do livro Necropolítica de Achille Mbembe
Authors: Ferreira Tatiana de Souza 
Published: November 2020

Filósofo de origem camaronesa, Achille Mbembe vem adquirindo crescente notoriedade no Brasil, tanto nas universidades quanto entre diferentes movimentos sociais. A difusão de suas ideias se deve em larga medida ao trabalho intitulado Necropolítica. Neste ensaio, Mbembe reflete sobre as condições de produção de mundos de morte em territórios sob o signo dos empreendimentos coloniais desde o século XV e da ocupação colonial na modernidade tardia. Profundamente geográfico, o ensaio Necropolítica contribui à reflexão sobre novas perspectivas para consolidados conceitos geográficos.
UMA ANÁLISE DA TRAJETÓRIA DO PDE-PR NA PERSPECTIVA DE PROFESSORES FORMADORES DA ÁREA DE MATEMÁTICA
Authors: Silva Priscila Gleden Novaes da , Boscarioli Clodis , Vertuan Rodolfo Eduardo 
Published: November 2020

O PDE-PR é uma política pública de formação continuada que entre 2007 e 2016 se configurou como uma parceria entre Instituições de Ensino Superior e Educação Básica, tendo mudado de formato após esse período. Apresentamos, neste artigo, as percepções de professores formadores da UNIOESTE, que atuaram na primeira fase do PDE-PR, na área de Matemática, sobre o Programa e os possíveis efeitos dessa participação em sua prática. Um questionário foi enviado para quarenta e nove desses docentes, dos quais obtivemos vinte e nove respondentes. Das análises dasrespostas emergiram suas percepções, apresentando, como principais aspectos positivos a aproximação da Educação Básica ao Ensino Superior; a reflexão de problemas ligados às escolas e ao trabalho do professor; e o afastamento remunerado. Como aspectos negativos foram citados a ascensão exclusiva eobrigatória na carreira por meio do Programa; o desinteresse manifesto em alguns professores; e a seleção dos professores, em geral, já próximos à aposentadoria. Quanto aos efeitos dessa formação na própria prática, foram elencados, como avanço, a aproximação com a realidade escolar e, como desafio, a orientação em áreas diferentes de sua formação e atuação. No formato atual, as principais mudanças dizem respeito ao fato de que não é mais oportunizada uma formação de caráter coletivo, com participação das Universidades e com direito ao professor de afastamento remunerado para a formação, o que exclui pressupostos norteadores confirmados como pontos positivos do Programa.
NARRATIVAS DA FORMAÇÃO E DA ATUAÇÃO DO PEDAGOGO NO PROCESSO DE ENSINO E APRENDIZAGEM DA MATEMÁTICA NOS ANOS INICIAIS DO ENSINO FUNDAMENTAL
Authors: Junior Wagner Alvarenga Vieira , Oliveira Sandra Alves de 
Published: November 2020

Este estudo tem como temática central de sua discussão a formação teórico-metodológica do professor que ensina matemática nos anos iniciais do ensino fundamental, o pedagogo. Busca-se analisar os sentidos atribuídos, por estudantes egressas do curso de Pedagogia do Campus XII da Universidade do Estado da Bahia (UNEB), à sua formação matemática e à sua atuação como professoras nos anos iniciais do ensino fundamental; e identificar as contribuições e os desafios da formação matemática nessa atuação. Para tanto, as análises ao longo do texto se respaldam em estudos já realizados nessa vertente, como também em narrativas escritas por estudantes egressas do referido curso. Esta pesquisa de abordagem qualitativa utilizou-se da recolha dos dados dos seguintes instrumentos metodológicos: questionário e narrativas elaboradas pelas seis estudantes egressas da Pedagogia, que atuam como professoras de matemática nos anos iniciais. Os achados da pesquisa alertam para a importância de ser revista a matriz curricular do curso de Pedagogia em relação à formação matemática do pedagogo, pois há apenas um componente curricular com a carga horária de 60 horas/aula que aborda essa questão, o que tem inviabilizado a aprendizagem significativa dossaberes matemáticos. Ademais, o conteúdo, por ser parte imprescindível desse saber, deve ser valorizado e aprofundado não apenas teoricamente, mas também na prática do professor que ensina matemática.
Semi-Active Scissors-Seat Suspension With Magneto-Rheological Damper
Authors: Zhu Hongtao , Rui Xiaoting , Yang Fufeng , Zhu Wei , Gu Junjie 
Published: November 2020

A cab seat suspension with a magneto-rheological (MR) fluid damper is introduced in this paper. A unified-format model for the MR damper is proposed to describe the dynamic characteristics of the MR damper. Also, a simple force-inverse model and a viscous damping tracking model are used for the coil current solution. A digital integrator and an extended Kalman filter are respectively adopted to obtain the vibration velocity of the chair frame and the relative motion velocity of the MR damper piston. A new skyhook control base with viscous damping tracking is applied to the semi-active seat suspension. In the simulation, compared with passive seat suspension under different displacement excitation (2, 4, 6, 8 Hz-sine, and random), the acceleration root mean square of the seat suspension with the MR damper is reduced by 52.2%, 32.2%, 41.3%, 50.8%, and 34.6%, respectively. In the experiment, the acceleration root mean square is reduced by 11.2%, 41.2%, 45.8%, and 31.5%, respectively under different displacement excitation (2, 4, 6, and 8 Hz-sine).
Using Poloxamer® 407 as Building Block of Amphiphilic Poly(ether urethane)s: Effect of its Molecular Weight Distribution on Thermo-Sensitive Hydrogel Performances in the Perspective of Their Biomedical Application
Authors: Laurano Rossella , Abrami Michela , Grassi Mario , Ciardelli Gianluca , Boffito Monica , Chiono Valeria 
Published: November 2020

Due to its hydroxyl terminal groups, Poloxamer® 407 (P407), a commercially available poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) triblock copolymer can be used as macrodiol for the synthesis of high molecular weight amphiphilic poly(ether urethane)s (PEUs). This work was aimed at studying the effect of P407 purification by removing PEO-PPO diblock copolymer by-products on the chemical properties of PEU polymer and the physical properties of PEU hydrogels. Removal of PEO-PPO diblock copolymers (P407_P) was found to preserve the thermo-responsiveness of resulting hydrogels, although slightly lower gelation onset temperature (Tonset) was found for P407_P (15.3°C) vs. P407 (16.7°C) hydrogels (25% w/V) as assessed through temperature ramp test. P407 and P407_P were then reacted with 1,6-diisocyanatohexane and 1,4-cyclohexanedimethanol to synthesize two different PEUs, coded as CHP407 and CHP407_P, respectively. Lower Number Average Molecular Weight (Mn¯) and higher polydispersity Index (D) was measured for CHP407 (Mn¯: 34 kDa, D: 1.6) respect to CHP407_P (Mn¯: 40 kDa, D: 1.4) as a consequence of macrodiol purification. CHP407_P hydrogels formed bigger micelles (43.9 ± 4.1 nm vs. 28.7 ± 4 nm) while showed similar critical micellar temperatures (22.1°C vs. 21.6°C) respect to CHP407 formulations. Sol-to-gel transition of CHP407 and CHP407_P hydrogels was similar while CHP407_P gelation time at 37°C was longer as assessed by tube inverting test. The rheological analysis showed slightly lower Tonset for CHP407_P hydrogels (15% w/V), probably due to larger micelle size, promoting micellar assembly. However, CHP407_P hydrogels showed a significantly lower critical strain than CHP407 hydrogels, as assessed by strain sweep test, suggesting their higher brittleness due to a lower density of intermicellar bridge chains. Nano-scale hydrogel characterization by Low-Field Nuclear Magnetic Resonance spectroscopy supported previous findings, showing lower spin-spin relaxation time (i.e., 1,259 ms) for CHP407_P than for CHP407 hydrogels (i.e., 1,560 ms) at 37°C, which suggested the formation of a more tightly packed network for CHP407_P than CHP407 hydrogel. Finally, lower swelling capability and resistance against dissolution were measured for CHP407_P hydrogels. Overall, the here‐reported results suggested that the heterogeneous structure in the CHP407 hydrogel network caused by the presence of diblock copolymer-based macrodiols improved PEU hydrogel properties in light of their applicability in the biomedical field.
The Impact of Periodontal Disease on Hospital Admission and Mortality During COVID-19 Pandemic
Authors: Larvin Harriet , Wilmott Sheryl , Wu Jianhua , Kang Jing 
Published: November 2020

Introduction: COVID-19 has had a huge impact on society and healthcare and it has been suggested that people with periodontal disease are at risk of having worse outcomes from the disease. The aim of this study was to quantify the impact of periodontal disease on hospital admission and mortality during the COVID-19 pandemic.Materials and Methods: The study extracted UK Biobank participants who had taken a COVID-19 test between March and June 2020 (n = 13,253), of which 1,616 were COVID-19 positive (12%) and 11,637 were COVID-19 negative (88%). Self-reported oral health indicators of painful or bleeding gums and loose teeth were used as surrogates for periodontal disease, participants who did not report any of the aforementioned indicators were used as controls. Multivariable logistic regressions were used to obtain crude and adjusted odds ratios of COVID-19 infection, subsequent hospital admission and mortality adjusted for demographics, BMI, biomarkers, lifestyle and co-morbidities.Results: Painful gums, bleeding gums and loose teeth were reported in 2.7, 11.2 and 3.3% of participants with COVID-19 infection, respectively. Risk of COVID-19 infection in participants with painful or bleeding gums and loose teeth compared to controls was not increased (odds ratio [OR]: 1.10, 95% CI: 0.72–1.69; OR: 1.15, 95% CI: 0.84–1.59). COVID-19 positive participants with painful or bleeding gums had a higher risk of mortality (OR: 1.71, 95% CI: 1.05–2.72) but not hospital admission (OR: 0.90, 95% CI: 0.59–1.37). Participants with loose teeth did not show higher risk of hospital admission or mortality compared to the control group (OR = 1.55, 95% CI: 0.87–2.77; OR: 1.85; 95% CI: 0.92–2.72).Conclusion: There was insufficient evidence to link periodontal disease with an increased risk of COVID-19 infection. However, amongst the COVID-19 positive, there was significantly higher mortality for participants with periodontal disease. Utilization of linked dental and hospital patient records would improve the understanding of the impact of periodontal disease on COVID-19 related outcomes.
Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Behavior Disorder
Authors: Sumi Yukiyoshi , Nakayama Chikao , Kadotani Hiroshi , Matsuo Masahiro , Ozeki Yuji , Kinoshita Takafumi , Goto Yuki , Kano Manabu , Yamakawa Toshitaka , Hasegawa-Ohira Masako , Ogawa Keiko , Fujiwara Koichi 
Published: November 2020

Background: Orthostatic hypotension (OH) caused by autonomic dysfunction is a common symptom in older people and patients with idiopathic rapid eye movement sleep behavior disorder (iRBD). The orthostatic challenge test is a standard autonomic function test that measures a decrease of blood pressure during a postural change from supine to standing positions. Although previous studies have reported that changes in heart rate variability (HRV) are associated with autonomic dysfunction, no study has investigated the relationship between HRV before standing and the occurrence of OH in an orthostatic challenge test. This study aims to examine the connection between HRV in the supine position and the occurrence of OH in an orthostatic challenge test.Methods: We measured the electrocardiograms of patients with iRBD and healthy older people during an orthostatic challenge test, in which the supine and standing positions were held for 15 min, respectively. The subjects were divided into three groups: healthy controls (HC), OH-negative iRBD [OH (–) iRBD], and OH-positive iRBD [OH (+) iRBD]. HRV measured in the supine position during the test were calculated by time-domain analysis and Poincaré plots to evaluate the autonomic dysfunction.Results: Forty-two HC, 12 OH (–) iRBD, and nine OH (+) iRBD subjects were included. HRV indices in the OH (–) and the OH (+) iRBD groups were significantly smaller than those in the HC group. The multivariate logistic regression analysis for OH identification for the iRBD groups showed the model whose inputs were the HRV indices, i.e., standard deviation 2 (SD2) and the percentage of adjacent intervals that varied by more than 50 ms (pNN50), had a receiver operating characteristic curve with area under the curve of 0.840, the sensitivity to OH (+) of 1.000, and the specificity to OH (–) of 0.583 (p = 0.023).Conclusions: This study showed the possibility that short-term HRV indices in the supine position would predict subsequent OH in iRBD patients. Our results are of clinical importance in terms of showing the possibility that OH can be predicted using only HRV in the supine position without an orthostatic challenge test, which would improve the efficiency and safety of testing.
Clinicopathologic Features and Prognosis of BRAF Mutated Colorectal Cancer Patients
Authors: Guan Wen-Long , Qiu Miao-Zhen , He Cai-Yun , Yang Li-Qiong , Jin Ying , Wang Zhi-Qiang , Li Yu-Hong , Xu Rui-Hua , Wang Feng-Hua 
Published: November 2020

Background:BRAFV600E mutation is associated with poor prognosis of colorectal cancer (CRC) patients, but the comparison of clinic-pathologic features between V600E and non-V600E mutation was not well-known in CRC patients. The aim of this study is to evaluate the clinical and pathological features, prognostic value of BRAF mutations in CRC.Methods: We conducted a retrospective study to characterize the clinical and pathological features and survival of patients with BRAF mutated CRC. Patients were classified according to BRAF status as BRAFV600E mutation and non-V600E mutations. Difference of characteristics and survival between the two groups was analyzed.Results: There was no significant difference in gender, family history, location of primary tumor, metastatic sites between patients with BRAF-V600E mutation and non-V600E mutations. Patients with V600E mutation were younger than those with non-V600E mutations (p = 0.002). Patients with BRAFV600E mutation showed a poorer outcome than those with non-V600E mutations (23.1 vs. 49.9 months, respectively, p = 0.0024). Lack of CDX2 expression was associated with worse prognosis (mOS: 9.4 m vs. not reached, respectively, p = 0.016). Status of V600E mutation did not affect the mPFS and ORR of first-line or second-line treatment.Conclusion:BRAFV600E mutation defines a distinct subgroup of CRC with worse prognosis. Lack of CDX2 expression is associated with poor OS. Status of V600E mutation did not affect the mPFS of first-line or second-line treatment.