bluuebunny/crossref_metadata_2025_split huggingface dataset:
A distinct metabolic state arises during the emergence of 2‐cell‐like cells
Authors: Rodriguez‐Terrones Diego , Hartleben Götz , Gaume Xavier , Eid André , Guthmann Manuel , Iturbide Ane , Torres‐Padilla Maria‐Elena 
Published: December 2019

AbstractPluripotent stem cells are thought of as a surrogate of early developmental stages that sustain the capacity to generate all cell types in the body, thereby constituting an invaluable tool to address the mechanisms underlying cellular plasticity. In the mouse, cells resembling totipotent 2‐cell‐stage embryos (2‐cell‐like cells) arise at a very low frequency in embryonic stem cell (ESC) cultures. However, the extent to which these early‐embryonic‐like cells recapitulate the molecular features of the early embryo is unclear. Here, we have undertaken a characterization of some of the metabolic features of early‐embryonic‐like cells in culture. Our data indicate that early‐embryonic‐like cells exhibit decreased glycolytic and respiratory activity, lower levels of reactive oxygen species and increased glucose uptake, suggesting a shift of the metabolic programme during 2‐cell‐like cell reprogramming. Accordingly, we find that 2‐cell‐like cells can be induced by defined metabolites. Thus, in addition to their transcriptional and chromatin features, 2‐cell‐like cells recapitulate some of the metabolic features of their in vivo counterpart. Altogether, our work underscores a distinct metabolic state of early‐embryonic‐like cells and identifies compounds that can induce their emergence in vitro.
Élaboration du Média de la Carte de Dessin Pour la Production Orale Intermédiaire Section Pédagogique de Français Université D’état Semarang
Authors: Septiani Arik , Widayanti Diah Vitri , Agustiningrum Tri Eko 
Published: December 2019

Il y a quatre compétences de langue, l'une est la production orale. C’est pareil avec le français, l'une des compétences à maîtriser est la production orale. Dans l’apprentissage de français, on a besoin de média pour pouvoir comprendre plus facilement les matières, en particulier dans la production orale, dans ce cas, la Production Orale Intermédiaire. Selon l'expérience, les étudiants ont souvent la difficulté à faire des phrases en raison du manque d'idées à prononcer, il serait mieux si on fait la variation de média d'apprentissage. On utilise la carte de dessin / flashcard accompagnée des mots auxiliaires qui permet les étudiants d'exprimer des idées ou des phrases. Cette recherche utilise la méthode de Recherche et Développement et nous adoptons 5 des 10 étapes de la recherche. Ce sont l'analyse de la potentialité et du problème, la collecte de données, la conception du produit, la validation du produit et l'examen du produit (Sugiyono, 2015: 408-427). Le média de la carte de dessin est le résultat de cette recherche. Ce produit contient 15 jeux de cartes. Chaque série est adaptée aux Plans d'Apprentissage Semestriels et aux thèmes du Taxi 2. Ce produit a été validé par l'expert et a été révisé selon les conseils de l'expert. Après l'examen, ce produit est prêt à être utilisé dans l'apprentissage de la production orale intermédiaire, mais l'efficacité doit être examinée.
There are four language skills, they are listening, speaking, reading and writing skill. As well as French, one of the skills that must be mastered is speaking skill. In learning French, we need the media to be more easily understand the material, especially in speaking skills, in this case Intermediate Oral Production. Based on experience, students often have difficulty to make sentences due to lack of ideas to be disclosed, so it would be better if we make the variation of learning media. We use the flashcard accompanied by auxiliary word that allows students to be able to express ideas or sentences. This research uses the method of Research and Development and we adopt 5 out of 10 stages of research. These are the analysis of potentiality and problem, data collection, product design, product validation, and product review (Sugiyono, 2015: 408-427). The media of the drawn map is the result of this research. This product contains 15 sets of cards. Each series is suitable for the Semester Learning Plans and the topics on The Taxi 2. This product has been validated by the expert and has been revised according to the expert's advice. After the review, this product is ready for use in learning Intermediate Oral Production, but the effectiveness needs to be examined.
Eksistensi Grup Musik Campursari Gondo Arum di Desa Bondo Kabupaten Jepara
Authors: Wiyono Jalu Sigit Aji , Sunarto Sunarto 
Published: December 2019

Abstrak
Penelitian ini bertujuan untuk mengetahui dan mendiskripsikan Eksistensi dan faktor yang mempengaruhi grup musik Campursari Gondo Arum di desa Bondo kabupaten Jepara. Penelitian ini dilakukan menggunakan metode kualitatif dengan pendekatan sosiologi. Pengumpulan data dilakukan dengan teknik observasi partisipasif, wawancara terstruktur dan semiterstruktur, serta dokumentasi. Analisis data dilakukan melalui tahapan pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa eksistensi grup musik Campursari Gondo Arum sudah cukup baik. Hal ini terbukti adanya: (1) tanggapan dari masyarakat an mendapatkan bantuan sarana prasarana dari pemerintah; (2) memanfaatkan teknologi dengan menambahkan sampling-sampling pada keyboard; (3) satu anggota grup ini memiliki gelar sarjana di bidang seni dan anggota lainnya bertamatkan sekolah menengah atas. Adapun faktor-faktor yang mempengaruhi eksistensi grup ini seperti; (1) manajemen dan pemasaran yang baik melalui media sosial; (2) performing music, yaitu grup ini memiliki ciri khas; (3) performing art, yaitu grup ini memiliki formasi dan konsep dalam pertunjukkannya.
MUSIK HIP – HOP DAN IDENTITAS DIRI KOMUNITAS DWELL DAN EXITO
Authors: Lubis Muhammad Akbar Hasyim 
Published: December 2019

Tulisan ini berjudul “Musik Hip-Hop dan Identitas Diri Komunitas Dwell dan Exito”. Dwell dan Exito merupakan represtasi dari komunitas-komunitas dan musisi-musisi hip-hop yang berada di kota Medan. Penelitian ini bertujuan untuk mengetahui proses pembentukan identitas dan untuk mengetahui faktor - faktor yang mempengaruhi pembentukan identitas dalam komunitas Dwell dan Exito. Penelitian ini menggunakan pendekatan deskriptif kualitatif dengan sumber data yang berasal dari informan yang berjumlah 5 orang. Teknik pengumpulan data yang digunakan yaitu, observasi, wawancara mendalam, serta tinjauan literatur. Hasil dari penelitian ini menunjukkan bahwa proses pembentukan identitas komunitas Dwell dan Exito terjadi secara bertahap yaitu dari tahap tidak mengetahui identitas dimana anggota tidak mengetahui tentang hip-hop, tahap pencarian identitas, dan tahap pencapaian identitas. Faktor-faktor yang mempengaruhi terbentuknya identitas diri atau dalam hal ini identitas hip-hop antara lain, masyarakat, diri, dan pikiran. Penggunaan simbol-simbol dapat dilihat dari 4 aspek yaitu, selera, keyakinan, sikap, dan gaya hidup.
Kata Kunci : Musik, Hip-Hop, Identitas diri, Penggunaan simbol - simbol.
"Keroncong in Jamaican Sound"
Authors: A'yun Wildan Qurrata , Rachman Abdul 
Published: December 2019

Abstrak
Jenis musik saat ini sangatlah banyak dengan berbagai ciri khasnya. Di Bandung salah satu musik yang digemari remaja adalah musik ska atau Jamaican sound. Musik ini digemari oleh remaja karena iramanya yang asik untuk joget. Ada seorang musisi ska bernama Sir’iyai yang berupaya untuk memberikan varian baru pada musik Jamaican sound dengan memasukkan unsur musik keroncong agar musik keroncong dapat dinikmati oleh semua kalangan khususnya remaja. Tujuan dari penelitian ini adalah untuk mengetahui dan mendeskripsikan bagaimana inovasi musik ska keroncong dalam melestarikan musik keroncong di Bandung. Penelitian ini menggunakan pendekatan deskriptif kualitatif dengan teknik pengumpulan data yaitu observasi, wawancara, dan dokumentasi serta teknik pemeriksaan keabsahan data diperiksa dengan metode triangulasi data. Teknik analisis data dalam penelitian ini menggunkan reduksi data, penyajian data, dan penarikan kesimpulan.Hasil penelitian menunjukkan bahwa Sir’iyai melakukan sebuah inovasi dengan memasukkan unsur musik keroncong ke dalam musik Jamaica khususnya musik ska. Alat musik yang digunakan meliputi alat musik band, brass section dan alat musik keroncong. pembawaan dari masing-masing alat musik tersebut menghasilkan sebuah genre musik baru dengan warna dan pola irama yang baru. Dengan inovasi tersebut, terbukti banyak remaja yang tertarik dan menikmati musik tersebut. Dengan demikian, musik keroncong tetap lestari dan lebih dikenal oleh remaja melalui musik ska atau Jamaican sound.
Human Corruption as The Effect of Modern Technology as Represented in Okky Madasari's "The Last Crowd"
Authors: Johariani Hana Septiana , Hetami Fatma 
Published: December 2019

Modern technology plays big roles in influencing human life, especially millenial generation. However , it can create human corruption due to its function abuse. The objectives of this study are: 1) to explain how human corruption is described in Okky Madasari’s The Last Crowd and 2) to explain how the modern technology creates human corruption as described in Okky Madasari’s The Last Crowd. The methodology used in this study was descriptive-qualitative. This study analyzed the novel using Levi Strauss’ theory. There were two objects of the study, namely material object which was The Last Crowd novel and formal object from the analysis of the novel using Levi Strauss’ theory. The results of the study are as follows: 1) Human Corruption was described in Okky Madasari’s The Last Crowd through how the characters in the novel use modern technology unwise until it has a bad effect. Human corruption is divided into three kinds of corruption; corruption in time, corruption in function and corruption in behavior. 2) Human Corruption is created due to the influence of technology towards Jayanegara, which triggers him to be trapped in it. It shows when he decides to make a pseudo-identity for being a winner and a revenger.

Keywords: Human Corruption; Modern Technology; Structuralism
An Analysis of the Symbol in Westlife's Song Lyrics
Authors: Rosita Hanna Eka , Purwanto Bambang , Rosyidi Mohamad Ikhwan 
Published: December 2019

Song is one example of literature. Listening song is enjoyable activity, but the listener cannot get a pleasure if they do not understand the meaning in the song. Sometimes song consists of symbol to describe the meaning of a song. Based on the reason, it brought the researcher to find out the symbol and meaning in the song lyrics and to explain the impacts of symbol toward real life. This study applied a descriptive qualitative method. Through this method the researcher tried to analyze, explain, and find out the meaning of the symbols by using Charles Sanders Pierce’s theory. In this case, Charles Sanders Pierce developed a triadic model in illustrating the definition of the sign as a symbol. The triadic model consisted of three components; representamen, object and interpretant. The unit analysis of this study were Westlife’s songs, there were more than 145 songs in 11 albums. Because of the large amount of the songs, the researcher chose 7 songs from the Greatest Album of Westlife that are Swear it Again, If I Let You Go, Flying without Wings, I Have a Dream, My Love, Uptown Girl, and You Raise Me Up. This study contained 5 kinds of symbols that were symbol of color (12 items), symbol of thing (19 items), symbol of situation (18 items), symbol of sound (5 items), and symbol of imaginative (7 items). Furthermore, the most dominant symbol was symbol of thing. Symbols brought some impacts to real life to help the listeners or the readers to understand the real meaning toward real life.

Keywords: Symbol; song; semiotics; westlife
Construction of American Hunger in Richard Wright's Novel "Black Boy"
Authors: Setiaji Febrian Ramadhani , Rosyidi Mohamad Ikhwan 
Published: December 2019

This study aims at explaining the construction of American hunger in Richard Wright’s novel Black Boy. This study is a qualitative analysis that relies on the power of word or explanatory reasoning. The data were collected by reading, identifying, classifying and analyzed using the structualism theories which used in this study by relating to binary operation to see the gap between black and white society. The results of this study were the segregation between black and white people in terms of the treatment, power, and superiority that in the end, it resulted that the black people are being treated different and has no right for freedom. The American Hunger is described in the novel through some events that go in the opposite between black and white people. The tention between them revealed from the different treatment, oppression, discrimination, superiority, and hunger that the black and white people or society experienced. The dominance and the power of the white people had harm the black people in some aspects in their life. Second, American Hunger that was described in the novel was regarded as the desire of the black people when they were living side by side with the white people in America. When the discrimination, segregation, and oppression occurs toward the black people, they satisfied their American hunger by standing agaisnt racial oppression, strengthen the superiority, and against the hunger.

Keywords: American hunger; construction; discrimination; structuralism
Myth as a Revelation of Spiritual Values for Today’s Human Life Reflected on Sarah H. Bradford’s "Harriet Tubman: The Moses of Her People"
Authors: Triana Ike Alit , Yulianto Henrikus Joko 
Published: December 2019

America is a country with Christianity as the major religion. It is the fact that Moses in Christian myth has an important role to the religion of this country. The United States President Harry Truman wrote in 1950 that the fundamental basis of the laws of the United States was the Ten Commandments that were given to Moses. America is also known for the country of freedom. Besides, American freedom has a unique historical story which is about slavery. Harriet Tubman: The Moses of Her People novel depicts the journey and struggle of Harriet in liberating African American slaves. This study aims to identify the incorporation of Moses in Christian myth to the story in the novel and its relation to the spiritual values of human’s life in the present time. The method of this study is qualitative study analysis using structuralism method of Claude Levi Strauss and the Study of Myth by Joseph Campbell. Then, the method of data analysis is based on the story in Harriet Tubman: The Moses of Her People novel and Moses in Christian myth. Bradford’s novel tells about the main character named Harriet who became the leader of African American slaves to the Northern America and Canada for freedom. While in Christian myth, Moses was chosen by God to be the leader of Israelites to go from the land of Egypt bondage for freedom. The final finding of this study shows the conflict of the novel, the incorporation of Moses in Christian myth to the story in the novel and shows the Ten Commandments of Christianity influenced the spiritual values by Americans which is also still relevant today. For instance, most Americans are Christian as the values of the First Commandment; Americans commonly regard their society as the freest and best in the world as the value of the Eight Commandment; the right of American constitutional democracy to attempt to “pursue” happiness in their own way as long as they do not infringe upon the rights of others is a result of the Tenth Commandment; Although there are still some transgressions of one or more of the Commandments, there are somehow many other Americans who are still devoted to the Ten Commandments as moral principles in their daily life.
Keywords: African-American, Christian myth, Moses, Slavery, Structuralism
Marxismo y “normalización” filosófica en Colombia (1930-1960)
Authors: Pachón Soto Damián 
Published: December 2019

Este artículo se centra en el proceso de normalización en Colombia y se ha interesado de manera especial en la recepción de Marx no solo a nivel nacional, sino también en el estudio académico europeo. Todo esto en el contexto de la pregunta por cómo la historia social de la filosofía ha venido estudiando el consumo de la filosofía en Colombia, claro, sin descuidar ni dejar de lado el pensamiento precolombino y el proceso de europeización y occidentalización que hemos vivido a partir del siglo xvi.
SapTrap Assembly of Caenorhabditis elegans MosSCI Transgene Vectors
Authors: Fan Xintao , De Henau Sasha , Feinstein Julia , Miller Stephanie I , Han Bingjie , Frøkjær-Jensen Christian , Griffin Erik E 
Published: December 2019

Abstract
The Mos1-mediated Single-Copy Insertion (MosSCI) method is widely used to establish stable Caenorhabditis elegans transgenic strains. Cloning MosSCI targeting plasmids can be cumbersome because it requires assembling multiple genetic elements including a promoter, a 3′UTR and gene fragments. Recently, Schwartz and Jorgensen developed the SapTrap method for the one-step assembly of plasmids containing components of the CRISPR/Cas9 system for C. elegans. Here, we report on the adaptation of the SapTrap method for the efficient and modular assembly of a promoter, 3′UTR and either 2 or 3 gene fragments in a MosSCI targeting vector in a single reaction. We generated a toolkit that includes several fluorescent tags, components of the ePDZ/LOV optogenetic system and regulatory elements that control gene expression in the C. elegans germline. As a proof of principle, we generated a collection of strains that fluorescently label the endoplasmic reticulum and mitochondria in the hermaphrodite germline and that enable the light-stimulated recruitment of mitochondria to centrosomes in the one-cell worm embryo. The method described here offers a flexible and efficient method for assembly of custom MosSCI targeting vectors.
How existing things are invariably present as sense?
Authors: Listik Yonathan 
Published: December 2019

This article aims to explore Jean-Luc Nancy’s notion of sense as a key ontological concept. This concept, as it appears mainly in his Sense of the World (1997b), opens the possibility of a more profound understanding of his thesis. The effort in this article will not be an attempt to draw a map or a line in Nancy’s theory placing sense either as the starting point or as his central concept. Instead, it is an attempt to show that sense plays a significant role in Nancy’s understanding of world and finitude, as it becomes evident is his recurrent concern with Wittgenstein’s (1994) aphorism 6.41: that the sense of the world must stand outside the world. Nancy defines the world as a rapport of entities or existents to each other. So, the argument advanced here analyzes sense’s centrality to Nancy´s discussion on touch and the vital role touch has in the articulation between his comprehension of mitsein/être-avec and his elaboration of being as singular plural, in order to show that a focus on sense could bring forwards a relevant elucidation of Nancy’s ontological argument and its implications. *** Como as coisas existem como sentido ***Esse artigo tem como objetivo explorar de que maneira a noção de sentido é um conceito ontológico central na filosofia de Jean-Luc Nancy. Esse conceito, como ele aparece em Sense of the World (1997b), abre a possibilidade para um entendimento mais profundo de sua tese. Esse artigo não busca percorrer ou desenhar um mapa, ou ainda, uma linha, através da filosofia de Nancy, cujo o sentido se colocaria como ponto de partida ou como conceito central.O artigo mostra que sentido tem um papel fundamental na compreensão de Nancy sobre os conceitos de mundo e finitude, como é exemplificado, pelo autor, em sua análise do aforismo 6.41 de Wittgenstein (1994): o sentido do mundo deve estar fora do mundo. Nancy define mundo como relação entre entidades ou existências entre si. O ponto defendido aqui é que a centralidade do sentido para Nancy se apoia em sua discussão acerca do toque e em seu papel central na articulação entre mitsein/etre-avec. Tais conceitos, se considerados em paralelo a noção de ser singular-plural, podem iluminar a ontologia defendida por Nancy.Palavras-chave: Sentido. Ontologia. Desconstrução. Tocar. Estar com
Ruin probability for discrete risk processes
Authors: Tuden Ivana Geček 
Published: December 2019

Abstract
We study the discrete time risk process modelled by the skip-free random walk and derive results connected to the ruin probability and crossing a fixed level for this type of process. We use the method relying on the classical ballot theorems to derive the results for crossing a fixed level and compare them to the results known for the continuous time version of the risk process. We generalize this model by adding a perturbation and, still relying on the skip-free structure of that process, we generalize the previous results on crossing the fixed level for the generalized discrete time risk process. We further derive the famous Pollaczek-Khinchine type formula for this generalized process, using the decomposition of the supremum of the dual process at some special instants of time.
Korselt rational bases of prime powers
Authors: Ghanmi Nejib 
Published: December 2019

Abstract
Let N be a positive integer, be a subset of ℚ and . N is called an α-Korselt number (equivalently α is said an N-Korselt base) if α2p − α1 divides α2N − α1 for every prime divisor p of N. By the Korselt set of N over , we mean the set of all such that N is an α-Korselt number.
In this paper we determine explicitly for a given prime number q and an integer l ∈ ℕ \{0, 1}, the set and we establish some connections between the ql -Korselt bases in ℚ and others in ℤ. The case of is studied where we prove that is empty if and only if l = 2.
Moreover, we show that each nonzero rational α is an N-Korselt base for infinitely many numbers N = ql where q is a prime number and l ∈ ℕ.
On the multi-dimensional modal logic of substitutions
Authors: Ahmed Tarek Sayed , Mahmoud Mohammad Assem 
Published: December 2019

Abstract
We prove completeness, interpolation, decidability and an omitting types theorem for certain multi-dimensional modal logics where the states are not abstract entities but have an inner structure. The states will be sequences. Our approach is algebraic addressing varieties generated by complex algebras of Kripke semantics for such logics. The algebras dealt with are common cylindrification free reducts of cylindric and polyadic algebras. For finite dimensions, we show that such varieties are finitely axiomatizable, have the super amalgamation property, and that the subclasses consisting of only completely representable algebras are elementary, and are also finitely axiomatizable in first order logic. Also their modal logics have an N P complete satisfiability problem. Analogous results are obtained for infinite dimensions by replacing finite axiomatizability by finite schema axiomatizability.