bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Wisdom and Vision From the ACMEGS Inaugural Decade
Authors: Bagić Anto I. , Funke Michael E. , Burgess Richard C. 
Published: November 2020

Summary:
Concise history of fascinating magnetoencephalography (MEG) technology and catalog of very selected milestone preclinical and clinical MEG studies are provided as the background. The focus is the societal context defining a journey of MEG to and through clinical practice and formation of the American Clinical MEG Society (ACMEGS). We aspired to provide an objective historic perspective and document contributions of many professionals while focusing on the role of ACMEGS in the growth and maturation of clinical MEG field. The ACMEGS was born (2006) out of inevitability to address two vital issues—fair reimbursement and proper clinical acceptance. A beacon of accountable MEG practice and utilization is now an expanding professional organization with the highest level of competence in practice of clinical MEG and clinical credibility. The ACMEGS facilitated a favorable disposition of insurances toward MEG in the United States by combining the national replication of the grassroots efforts and teaming up with the strategic partners—particularly the American Academy of Neurology (AAN), published two Position Statements (2009 and 2017), the world's only set of MEG Clinical Practice Guidelines (CPGs; 2011) and surveys of clinical MEG practice (2011 and 2020) and use (2020). In addition to the annual ACMEGS Course (2012), we directly engaged MEG practitioners through an Invitational Summit (2019). The Society remains focused on the improvements and expansion of clinical practice, education, clinical training, and constructive engagement of vendors in these issues and pivotal studies toward additional MEG indications. The ACMEGS not only had the critical role in the progress of Clinical MEG in the United States and beyond since 2006 but positioned itself as the field leader in the future.
Community-level women’s education and hemoglobin level among Indian adolescents: A multilevel analysis of a national survey
Authors: Shah Ankita R. , Subramanyam Malavika A. 
Published: November 2020

AbstractBackgroundLittle research has explored the influence of social context on hemoglobin levels among Indian adolescents. We conceptualized community-level women’s education (proxy for value placed on women’s wellbeing) as exerting contextual influence on adolescent hemoglobin level.MethodsWe used the Indian National Family Health Survey 2015-16 data (62,648 adolescents aged 15-17 years). We fit multilevel random intercepts linear regression models to test the association of village- and urban-ward-level-women’s education with hemoglobin of adolescents, accounting for own and their mother’s education; plus relevant covariates.FindingsOur fully adjusted model estimated that if the 45% of communities with fewer than ten percent of women having a tenth-grade education in our sample were to achieve 100% high school completion in women, the average hemoglobin of all adolescents in such communities would be 0·22 g/dl higher (p<0·01). Unexplained variance at the contextual level remained statistically significant, indicating the importance of context on adolescent hemoglobin.InterpretationsAdolescents are deeply embedded in their context, influenced by contextual factors affecting health. Promoting adolescent health therefore implies altering social norms related to adolescent health and health behaviors; along with structural changes creating a health-promoting environment. Integrating our empirical findings with theoretically plausible understanding of the pathways connecting community-level women’s education with adolescent hemoglobin, we suggest that enhancing community-level women’s education beyond high school is necessary to facilitate these processes.ImplicationsAddressing contextual determinants of adolescent hemoglobin might be the missing link in India’s adolescent anemia prevention efforts, which are focused heavily on individual-level biomedical determinants of the problem.
Bayesian network modelling for early diagnosis and prediction of Endometriosis
Authors: Collins Rachel , Fenton Norman 
Published: November 2020

AbstractBayesian networks (BNs) are graphical models that can combine knowledge with data to represent the causal probabilistic relationships between a set of variables and provide insight into the processes underlying disease progression, closely resembling clinical decision-making. This paper describes a BN causal model for the early diagnosis and prediction of endometriosis. The causal structure of the BN model is developed using an idioms-based approach and the model parameters are derived from the data reported in multiple medical observational studies and trials. The BN incorporates the impact of errors and omissions in reporting endometriosis, and the distinction between assumed and actual cases. Hence, it is also able to explain both flawed and counterintuitive results of observational studies.
Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death
Authors: Gisby Jack , Clarke Candice L. , Medjeral-Thomas Nicholas , Malik Talat H. , Papadaki Artemis , Mortimer Paige M. , Buang Norzawani B. , Lewis Shanice , Pereira Marie , Toulza Frederic , Fagnano Ester , Mawhin Marie-Anne , Dutton Emma E. , Tapeng Lunnathaya , Richard Arianne C. , Kirk Paul D. W. , Behmoaras Jacques , Sandhu Eleanor , McAdoo Stephen P. , Prendecki Maria F. , Pickering Matthew C. , Botto Marina , Willicombe Michelle , Thomas David C. , Peters James E. 
Published: November 2020

AbstractEnd-stage kidney disease (ESKD) patients are at high risk of severe COVID-19. We measured 436 circulating proteins in serial blood samples from hospitalised and non-hospitalised ESKD patients with COVID-19 (n=256 samples from 55 patients). Comparison to 51 non-infected patients revealed 221 differentially expressed proteins, with consistent results in a separate subcohort of 46 COVID-19 patients. 203 proteins were associated with clinical severity, including IL6, markers of monocyte recruitment (e.g. CCL2, CCL7), neutrophil activation (e.g. proteinase-3) and epithelial injury (e.g. KRT19). Machine learning identified predictors of severity including IL18BP, CTSD, GDF15, and KRT19. Survival analysis with joint models revealed 69 predictors of death. Longitudinal modelling with linear mixed models uncovered 32 proteins displaying different temporal profiles in severe versus non-severe disease, including integrins and adhesion molecules. These data implicate epithelial damage, innate immune activation, and leucocyte-endothelial interactions in the pathology of severe COVID-19 and provide a resource for identifying drug targets.
Children hospitalized for COVID-19 during the first winter of the pandemic in Buenos Aires, Argentina
Authors: Raiden Silvina , Cairoli Hector , Potasnik Javier , Di Lalla Sandra , Chiolo María José , Torres Fernando , Dominguez Paula , Ferrero Fernando 
Published: November 2020

ABSTRACTBackgroundAlthough there are reports on COVID-19 in pediatrics, it is possible that the characteristics of each population, their health systems and how they faced the pandemic made the disease show distinctive features in different countries.ObjectiveWe aimed to describe the characteristics of patients hospitalized for COVID-19 in a tertiary pediatric hospital in the City of Buenos Aires, Argentina.MethodsDescriptive study, including all patients hospitalized for COVID-19 in a tertiary pediatric hospital, from 04/26/2020 to 10/31/2020. Demographic, clinical and epidemiological characteristics of the patients are described.ResultsIn the studied period 578 patients were hospitalized for COVID-19. The median age was 4.2 years and 83% had a history of close contact with a confirmed COVID-19 case. Regarding severity, 30.8% were asymptomatic, 60.4% mild, 7.4% moderate, and 1.4% severe. Among those with symptoms, the most frequent was fever, followed by sore throat and cough.ConclusionWe reported 578 cases of children and adolescents hospitalized for COVID-19, most of them showed a mild or asymptomatic condition.
Severity of Respiratory Infections due to SARS-CoV-2 in Working Population: Age and Body Mass Index Outweigh ABO Blood Group
Authors: Schetelig Johannes , Baldauf Henning , Wendler Sarah , Heidenreich Falk , Real Ruben , Kolditz Martin , Rosner Andrea , Dalpke Alexander , de With Katja , Lange Vinzenz , Markert Jan , Barth Ralf , Bunzel Carolin , Endert Dennis , Hofmann Jan A , Sauter Jürgen , Bernas Stefanie N , Schmidt Alexander H 
Published: November 2020

AbstractBackgroundWith increasing rates of SARS-CoV-2 infections and the intention to avoid a lock-down, the risks for the working population are of great interest. No large studies have been conducted which allow risk assessment for this population.MethodsDKMS is a non-profit donor center for stem cell donation and reaches out to registered volunteers between 18 and 61 years of age. To identify risk factors for severe COVID-19 courses in this population we performed a cross-sectional study. Self-reported data on oro- or nasopharyngeal swabs, risk factors, symptoms and treatment were collected with a health questionnaire and linked to existing genetic data. We fitted multivariable logistic regression models for the risk of contracting SARS-CoV-2, risk of severe respiratory infection and risk of hospitalization.FindingsOf 4,440,895 contacted volunteers 924,660 (20.8%) participated in the study. Among 157,544 participants tested, 7,948 reported SARS-CoV-2 detection. Of those, 947 participants (11.9%) reported an asymptomatic course, 5,014 (63.1%) mild/moderate respiratory infections, and 1,987 (25%) severe respiratory tract infections. In total, 286 participants (3.6%) were hospitalized for respiratory tract infections. The risk of hospitalization in comparison to a 20-year old person of normal weight was 2.1-fold higher (95%-CI, 1.2-3.69, p=0.01) for a person of same age with a BMI between 35-40 kg/m2, it was 5.33-fold higher (95%-CI, 2.92-9.70, p<0.001) for a 55-year old person with normal weight and 11.2-fold higher (95%-CI, 10.1-14.6, p<0.001) for a 55-year old person with a BMI between 35-40 kg/m2. Blood group A was associated with a 1.15-fold higher risk for contracting SARS-CoV-2 (95%-CI 1.08-1.22, p<0.001) than blood group O but did not impact COVID-19 severity.InterpretationIn this relatively healthy population, the risk for hospitalizations due to SARS-CoV-2 infections was moderate. Age and BMI were major risk factors. These data may help to tailor risk-stratified preventive measures.FundingDKMS initiated and conducted this study. The Federal Ministry of Education and Research (BMBF) supported the study by a research grant (COVID-19 call (202), reference number 01KI20177).
Commercial lender judgments and fair-value recognition: an investigation into the impact of future accounting standards
Authors: Warne Rick C. 
Published: November 2020

PurposeThis paper examines the impact that fair-value recognition of non-financial assets has on the judgments of commercial lenders.Design/methodology/approachCommercial lenders, who were attending a national banking conference, participated in a controlled experiment.FindingsThe experimental results show that commercial lenders incorporate fair values into their judgments but only when this information is recognized (vs disclosed) on the financial statements. Additionally, lenders assigned the highest loan interest rates when recognized fair values increased net income, and they assign the lowest loan amounts when recognized fair values decreased net income.Research limitations/implicationsTypical limitations regarding behavioral experiments are acknowledged in the paper. For example, the commercial lenders in this study could not request additional information. In addition, because of the difficulty in obtaining these participants, the sample size is relatively small.Practical implicationsUS Generally Accepted Accounting Principles (GAAP) does not allow the fair-market valuation for most non-current assets while International Financial Reporting Standards (IFRS) require such valuations. The article adds to our understanding about how a significant user group of financial statements, commercial lenders, view GAAP and IFRS accounting.Social implicationsThis article provides insights regarding how commercial lenders' decisions may change based on accounting principles related to asset valuation. Obtaining credit through loans has significant implications for society.Originality/valueThis article is unique because it examines commercial lenders' judgments using different asset valuations on the financial statements.
Peebuddy: ladies, it’s time to stand-up!
Authors: Neena Sondhi , Rituparna Basu 
Published: November 2020

Supplementary materialsTeaching Note and Exhibits.Learning outcomesThe learning outcomes are as follows. The case offers a rare opportunity to understand the unique market dynamics of feminine health and hygiene products in an emerging market. The discussion would enable learners to comprehend different stages of “new product development process”; understand “diffusion of innovation” and consumer adoption process; conduct a comprehensive situation analysis to assess segment attractiveness; and plan market-driven “product commercialization” strategies to increase adoption and sales for long-term performance.Case overview/synopsisPeebuddy – “India’s first portable female urination device” that gave women the freedom to stand and pee in unfriendly toilets was launched in 2015. Over two million units were sold by December 2019. Riding on this success, Deep Bajaj – the creator of Peebuddy built a 20-product company from a small bootstrapped start-up, over a four-year period. After receiving two rounds of funding, Bajaj knew that for the next phase of expansion, he needed to showcase Peebuddy as the star product. Facing the challenge of getting over the chasm of limited adoption of an unconventional product in the intimate feminine hygiene and almost taboo space in an emerging market such as India, Bajaj was determined to retain the first mover advantage and emerge as the leader in the category. For this, he had to define his lead user distinctly and design appropriate strategies to increase consumer reach and sales that could overcome the challenges of cultural stereotypes.Complexity academic levelMBA-level courses in marketing management (core), consumer behavior and product management.Subject codeCSS 8: Marketing.
Learning huddles: absorptive capacity and sustainable growth of Chinese incubatees
Authors: Kennett Geraldine , Hu Ling , Maritz Alex , Sun He 
Published: November 2020

PurposeThis study explores the different learning practices of Chinese incubators in Chongqing and Chengdu and delves into how these “learning huddles” influence incubatees' absorptive capacity (the ability to apply knowledge) to improve their chance of success (sustainable growth).Design/methodology/approachThis explorative study uses a qualitative case study approach by means of semi-structured interviews with business incubation managers and incubatees across three business incubators in Chengdu and Chongqing. The data are transcribed, coded and analyzed using an analytic map for the explanation of building and reflecting on the theoretical propositions, leading to a further understanding of the “learning huddle” mechanism.FindingsThe study finds that incubatees perceive that their absorptive capacity is increased through vicarious informal learning practices that promote access to networks and thereby builds social capital to improve their likelihood of success.Research limitations/implicationsThis study has limitations in sample size and design. The explorative case study approach uses a nonrandom case selection of three incubators in Chongqing and Chengdu and has a limited number of interviewees, which may lack representation of the general Chinese business incubation population and may not sufficiently be generalized beyond the sample itself.Practical implicationsThese findings have important implications for business incubation programs. Business incubators that build learning huddles (networks) create a nurturing shared learning environment, which is suitable for incubatees to collectively absorb knowledge at the early stage of their life cycle and improve their likelihood of sustainable growth.Social implicationsSince this study is limited to a Chinese context, it is also hoped that future researchers use the typology of business incubator learning practices to explore cross-culture variables, as these may influence the business incubation operations and performance.Originality/valueThis study adds to the discussion on how collective learning practices facilitate absorptive capacity and build social capital, which in turn improves incubatees' chance of sustainable growth and as such the authors hope that the learning practice's typology and how incubatees determine their success stimulates further research for measuring the likelihood of incubatees sustainable growth.
The influence of institutional pressures on the implementation of a performance measurement system in an Egyptian social enterprise
Authors: Alsaid Loai Ali Zeenalabden Ali , Ambilichu Charles Anyeng 
Published: November 2020

Purpose
This study aims to explore the influence of field-level funding pressure and resource dependency on conflicting institutional logics in implementing a new performance measurement system (PMS) within a privatised social enterprise (SE) in a developing country. It answers the research question: how accounting-based key performance indicators (KPIs) were chosen within a privatised SE to maintain co-existence between two different institutional logics, the social and commercial logics, to gain legitimacy in the government funding scheme.

Design/methodology/approach
This study expands the application and contribution of the Besharov and Smith’s (2014) logics multiplicity framework to previous management accounting literature on PMS and institutional logics. It adds a new dimension to previous literature to theorise the cognitive dynamics of institutional logics at three distinct but interrelated institutional levels, namely, field, organisational and individual. Data come from an interpretive case study of an Egyptian SE, involved in implementing a social project (drinking water refining) in rural communities.

Findings
PMS acts as a political tool through which the privatised case company has gained societal acceptance and legitimacy in the government funding scheme. Its non-political KPIs have turned into political tools to meet the institutional demands of the funding scheme. This government involvement represents field-level institutional logics, which influenced the organisational-level interplay of commercial and social logics and then the individual-level choice of internal KPIs. This contributes to the fact that institutional logics and their interplay between these three levels are “in a state of flux” within SEs’ internal PMS.

Originality/value
This study deals with a real-life practical case that proves the prevalence of one institutional logic over another at both the organisational and individual levels may be occasioned by organisational field pressures and opportunities rather than by other intra-organisational conflicts as discussed in most previous literature on PMS and institutional logics.
Two cases of severe congenital hypotrichosis caused by compound heterozygous mutations in the LSS gene
Authors: Murata Mami , Hayashi Ryota , Kawakami Yoshio , Morizane Shin , Shimomura Yutaka 
Published: November 2020

AbstractIt has recently been shown that bi‐allelic mutations in the lanosterol synthase (LSS) gene, which was originally reported as a causative gene for congenital cataracts, underlie a non‐syndromic form of hypotrichosis. Furthermore, it has also been revealed that mutations in the LSS gene can cause syndromic forms of hypotrichosis. To date, however, clear genotype–phenotype correlations have not completely been characterized. In this study, we identified two Japanese patients who had severe congenital hypotrichosis without any other associated findings. Their scalp hairs were extremely short and thin, and were able to be plucked easily. Observation of the plucked hairs showed aberrantly‐miniaturized anagen hair follicles. Genetic analysis demonstrated that both patients carried bi‐allelic mutations in the LSS gene in a compound heterozygote state. Our findings further underscore the crucial roles of the LSS gene in hair follicle development and hair growth in humans.
Sex differences in alternative reproductive tactics in response to predation risk in tree crickets
Authors: Torsekar Viraj R. , Balakrishnan Rohini 
Published: November 2020

Abstract

Alternative reproductive tactics (ARTs) are variable, often discontinuous, behaviours that allow a particular sex to achieve enhanced mating success. Predation risk has been hypothesised to drive the evolution of ARTs, but few empirical studies have examined this. It is unclear whether predators affect fitness of the two sexes directly, by reducing survival, or indirectly, by altering mate searching.

In crickets, mate search typically involves acoustic signalling by males and acoustic‐mediated movement towards males by silent females. Males and females may however employ ARTs, which includes silent searching by males, and mating without performing phonotaxis in females.

We empirically examined effects of increased predation risk on mate searching behaviour and survival of male and female tree crickets, and their effects on mating success, using field‐enclosure experiments with tree crickets Oecanthus henryi and their primary predator, green lynx spiders Peucetia viridans. Crickets were allocated into three treatments with different levels of predation risk.

Increased predation risk strongly reduced survival, and thereby mating success, for both sexes. With increasing predation risk, males reduced calling and increased movement towards neighbouring callers, with negative effects on mating success. By comparing with simulated random movement, we found that male movement was significantly directed towards other calling males, implying a switch to satellite strategies. Female movement behaviour, however, remained unaltered.

Males and females thus differed in their response to comparable levels of predation risk, implying that the role of predation as a driver of alternative mate search strategies is sex‐specific.

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