bluuebunny/crossref_metadata_2025_split huggingface dataset:
Repercussões do abuso e exploração sexual na criança e adolescente e a importância da qualificação da enfermagem frente aos casos: revisão narrativa
Authors: Aleluia Emilie dos Santos , De Carvalho Maria Ledijane Reis , Bomfim Vitoria Vilas Boas da Silva , Dias Mariza Araujo dos Santos , Leal Victor de Matos , De Almeida Aglaya Oliveira Lima Cordeiro , Santa Fé Ana Flora Sena , Rocha Rebeca Pereira da 
Published: July 2020

Objetivo: analisar de acordo com a literatura as repercussões do abuso e exploração sexual na criança e adolescente bem como destacar a importância da qualificação profissional da enfermagem e das notificações frente aos casos. Revisão Bibliográfica: O abuso e exploração sexual infantil consistem na violação dos direitos sexuais de crianças e adolescentes de forma não consensual e impositiva, envolvendo essa população em atividades sexuais inapropriadas para sua maturidade física e psicológica trazendo diversas repercussões na vida do indivíduo, sendo apontada como uma das principais causas de morbimortalidade no Brasil tornando-se grande problema de saúde pública. Diante disso constatou-se a importância da enfermagem na abordagem do abuso sexual, visto que é a maior equipe de uma unidade de saúde, assumindo o papel de protagonismo na abordagem do tema, requerendo assim conhecimento científico e domínio para notificar os casos de forma precisa. Considerações Finais: O abuso e a exploração sexual infanto-juvenil causam severos distúrbios comportamentais e emocionais na vítima que vão desde abuso de substâncias psicoativas ao pensamento autodestrutivo. É essencial e urgente a qualificação do enfermeiro, visto que há um descompasso entre a atuação de enfermagem para identificar e notificar os abusos com as reais necessidades do menor.
Persepsi User Experience Terhadap Aplikasi Pesan Antar Makanan Online (Studi Kasus Pengguna Aplikasi Madhang.id)
Authors: Prabowo Dwi Puji , Yanuarsari Dzuha Hening , Pramunendar Ricardus Anggi 
Published: July 2020

Menjamurnya permintaan masyarakat akan jasa pesan antar online membuat perusahaan yang bergerak dibidang kuliner secara online mulai bersaing dalam menyediakan jasa dan layanan yang baik. Salah satu sektor dalam pengembang bisnis tersebut adalah konteks marketing media salah satunya yakni lewat media `aplikasi. Aplikasi mampu menjangkau pangsa pasar secara luas sehingga memerlukan perhatian yang lebih dalam segi desain maupun konten terkait dengan pengalaman pengguna yang membuat mereka tertarik untuk menggunakan aplikasi tersebut. Madhang.id merupakan objek yang dikaji dalam penelitian ini dimana merupakan salah satu aplikasi yang menyediakan jasa pesan antar makanan secara online. Penelitian ini menawarkan kajian mengenai persepsi pengguna terhadap penggunan aplikasi madhang.id menggunakan konteks the four elements of user experience yang dibedah menggunakan metode deskriptif-kuantitatif. Luaran yang dihasilkan pada penelitian ini yakni berupa kajian dalam mencari tahu persepsi pengalaman pengguna menggunakan aplikasi madhang.id yang basisnya dikembangkan oleh perusahaan IT dimana manfaatnya dapat dijadikan sebagai bahan rujukan dalam pengembangan apliikasi serupa.
PENAMBAHAN EKSTRAK KULIT MANGGIS (Garcinia mangostana. L) DENGAN KOMPOSISI BERBEDA SEBAGAI PEWARNA ALAMI DALAM PENGOLAHAN TERASI BUBUK
Authors: Riyadi Slamet , Wiranata Arno , Jaya Fitra Mulia 
Published: July 2020

Terasi merupakan bumbu tradisional yang banyak disukai oleh masyarakat. Permasalahan penggunaan pewarna buatan terasi diduga dapat diatasi dengan penambahan ekstrak kulit manggis (Garcinia mangostana. L) yang kaya akan anthosianin. Perlakuan pada penelitian ini berupa penambahan Ekstrak Kulit Manggis pada pengolahan terasi dengan berbagai konsentrasi (B/B) yaitu : 0 %, 2.5 %, 5 %, 7.5 %, 10 % (dari berat bahan baku). Nilai analisa fisik dari hasil terasi bubuk terbaik terdapat pada perlakuan penambahan ekstrak kulit manggis 10 % (W5) dengan nilai lightness 47.61, chroma 27.11 dan hue 50.01. Nilai mutu organoleptik terasi bubuk terbaik terdapat pada perlakuan penambahan ekstrak kulit manggis 10 % (W5) dengan nilai Â warna 3.76 %, penampakan 3.60 %, aroma 3.52 %, rasa 3.60 %. Nilai mutu kimia terasi bubuk terbaik berdasarkan nilai mutu fisik danÂ organoleptik terbaik adalah kadar air Â 19.75%, abu 11.14%, protein 40.41%, lemak 2.00 %, karbohidrat 26.30 %.
EFFECTS OF CHRONIC EXPOSURE TO PARACETAMOL AND HIBISCUS SABDARIFFA LINN CALYX EXTRACT ON THE KIDNEY OF MICE
Authors: Orji Blessing Ogechukwu , Obi Frederick Otunuya , Ibrahim Maryam 
Published: July 2020

This study was conducted to evaluate the effects of concurrent administration of aqueous extract of Hibiscus sabdariffa Linn calyx and paracetamol on kidney injury induced by chronic exposure to paracetamol in mice. The study was carried out over 16 weeks. The animals were grouped into four (4): control (paracetamol and extract free), extract only, paracetamol only and co-administration of paracetamol with extract. The drug and extract were administered orally at 500 and 250 mg/kg body weight respectively by means of an oral gavage. In order to assess kidney function, electrolytes (sodium, bicarbonate, potassium and chloride), urea and creatinine were assessed in serum. Malondialdehyde (MDA) and antioxidant status (superoxide dismutase and catalase activities, and reduced glutathione level) were estimated in kidney homogenate. Histopathological examinations of kidney sections were also carried out on the mice. Paracetamol toxicity was confirmed by significant increase (P ≤ 0.05) in urea and creatinine levels along with altered electrolyte concentrations. Co-administration of paracetamol with aqueous extract of Hibiscus sabdariffa Linn calyx significantly (P≤ 0.05) reversed the drug-induced alterations close to control, in most of the parameters assayed. The antioxidant activity of the extract is most likely due to its strong scavenging effect on reactive oxygen species and free radicals.
RENIN-INHIBITORY BIOACTIVE PEPTIDES WITH ANTIHYPERTENSIVE PROPERTY: A REVIEW
Authors: Bello Mada Sanusi , Paul Ugwu Chizoba , Musa Abarshi Muawiya , Saliu Muhammad Auwal 
Published: July 2020

Blood pressure is regulated by the renin angiotensin aldosterone system (RAAS). Renin-catalyzed conversion of angiotensinogen to angiotensin I is the rate-limiting step of the RAAS pathway, which arguably makes renin a better target for prevention, treatment and management of hypertension than Angiotensin-Converting Enzyme (ACE). Hydrolysis of food proteins releases bioactive peptides that can interact with receptors, enzymes and molecules in the organism to promote health. Several studies have shown that these bioactive peptides could be exploited for management of hypertension which is a major risk factor for cardiovascular diseases (CVDs). Antihypertensive peptides are bioactive peptides derived from plant and animal sources with inherent potential to ameliorate hypertension by different mechanism including scavenging of free radicals, reduced cholesterol level, inhibit angiotensin-converting enzyme (ACE) activity and renin production. Although there was sufficient information on ACE-inhibitory and antioxidative peptides while information on the potential role of renin-inhibitory peptides against hypertension is limited. Thus, herein the present review primarily used ISI, SCOPUS and PubMed indexed journals containing experimental reports to elucidate the potential role of bioactive peptides against antihypertensive effect via renin inhibition.

Key words: Hypertension; Bioactive peptides; Renin inhibition; Mechanism of action.
ASSESSMENT OF URBAN GENERATED CLIMATE ANOMALY IN OKENE TOWN, OKENE LOCAL GOVERNMENT AREA OF KOGI STATE, NIGERIA
Authors: Sunday Ishaya 
Published: July 2020

Abstract
This study assessed urban generate climate change in Okene town of Kogi State, Nigeria. The objectives of this study include acquiring temperature, relative humidity and solar radiation data from SWAT satellite image from 1986 to 2016; determine the trend, normality, changes in temperature, relative humidity and solar radiation in the study area from 1986 to 2016. Climate data was collected from the Soil and Water Assessment Tools (SWAT) from 1986 to 2016 of Okene Town. Simple Statistical Measures of mean, maximum, minimum, standard deviation, Average deviation, coefficient of variation, skewness and kurtosis were used for discerning the trends and normality of temperature, relative humidity and solar radiation. The chi square statistical test was use to test the study hypothesis. The trend line equation shows positive for temperature (0.0567x +26.27), Solar radiation (0.036x + 18.1) and negative trend in relative humidity (y = -0.001x + 0.733). Chi square statistical result shows that there are significant changes in temperature, relative humidity and solar radiation over the past three decades in Okene town of Kogi State. In tackling this anomaly, there is need for greening the town by embanking on radical planting of trees and creation of cool pavement technologies towards cooler surfaces by convection or higher reflectance as adaptive/mitigation measures against Urban Heat Island in Okene town.
TOXICOLOGICAL EFFECT OF INHALED MOSQUITO INCENSE STICKS SMOKE ON THE HISTOLOGY AND BIOCHEMICAL RESPONSES IN EXPERIMENTAL RATS
Authors: Nafiu Abdullahi Shafiu , Dahiru M. M. , Rabiu D. H. , Mohammed J. M. 
Published: July 2020

This study was carried out to investigate the toxicological effects of four brands of mosquito incense stick smoke (DR insecticide stick (AS-1987), Incense upgraded formula (BM-102), Fragrance (B3-254) and Citronella (A7-435) on selected biochemical and histological profile of male albino wistar rats. Fifteen (15) wistar rats with mean weight (174.6 ±0.91g) were randomly divided into five (5) groups. Group I were considered as negative control while group II, III, IV and V were challenged with the brands of mosquito incense stick smoke for 8 hours daily by inhalation for 21 days. Laboratory investigations were carried out using standard protocols. It was observed that the activities of the liver enzymes (Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST) and Alkaline Phosphatase (ALP) increased significantly (p<0.05) in all the experimental rats when compared with the control. The histopathological alterations examined in the liver tissues of the experimental rats during the study period include mild necrosis, mild degeneration of hepatocytes and cellular infiltration from group III, IV and V respectively. Lung tissues of the challenged rats of group II, III and V revealed mild cellular infilterations around alveolar septa, hyperplasia and bronchiolar epithelial wall degeneration respectively. Kidney tissues revealed glomeruli distortion, mild haemorrhage and renal damage from group III and IV respectively. The alterations examined in the liver, kidney and lung tissues of the experiment rats were period dependent but independent of mosquito sticks brands which inferred that continuous exposure to mosquito stick
DETERMINATION OF ORGANOCHLORINE PESTICIDE RESIDUES IN SOME VEGETABLES AND FRUIT BY QuEChERS TECHNIQUES AND GAS CHROMATOGRAPHY /MASS SPECTROMETRY
Authors: Suleiman F. , Nuhu A. A. , Omoniyi K. I. , Yashim Z. I. 
Published: July 2020

The concentrations of organochlorine pesticide residues were analysed in some vegetables and fruit (spinach, lettuce, cabbage, tomatoes, carrots and onions) grown at Dagachi farming areas along River Galma of Zaria in Kaduna State, Nigeria. Sample collection and preparation were carried out using standard procedures. The concentrations of all the pesticides in the fruits and vegetables samples were analysed using quick easy cheap effective rugged and safe (QuEChERS) multi- residue extraction and clean up techniques, followed by gas chromatography – mass spectrometry (GC – MS). The most commonly detected organochlorine pesticide residues in the entire samples analysed are lindane, delta – BHC, heptachlor epoxide (B), endosulfan I, dieldrin, and endosulfan II. Furthermore, the results of the study shows that the mean concentration of these organochlorines pesticide detected were higher in onion and spinach with heptachlor epoxide (B) having concentrations 2.303 mg/kg and 2.011 mg/kg respectively. Likewise, endosulfan II (1.433 mg/kg) in lettuce was observed. Heptachlor epoxide (B) detected were also very high in other samples such as carrot, cabbage, and tomatoes and with values 0.600 mg/kg, 0.716 mg/kg, and 0.524 mg/kg respectively. Indeed, these concentrations of all the organochlorine pesticides detected in the fruit and vegetables samples analysed were observed to be at alarming levels, much higher than the maximum residue limits (MRLs) by the Codex 2009 (WHO and FAO) except for lindane with values 0.007 mg/kg and 0.01 mg/kg in carrot and onions respectively
PEMERINTAH DAN PERANANNYA DALAM PELAYANAN PENGURUSAN KARTU TANDA PENDUDUK (KTP) DI KECAMATAN LUBUK BAJA KOTA BATAM
Authors: Sari Meri Enita Puspitasar 
Published: July 2020

Abstract This study is intended to see how the government service in the management of identity card (KTP) either from the apparatus or from its role. Identity Card (KTP) is one of the mandatory identity that must be owned by every citizen of Indonesia and has been regulated by the rules in effect so that in the implementation of society must get good service. A policy will be successfully implemented if the government apparatus in running it in the community in accordance with the role and rules that apply and the community must also accept and support the policy so that there is a good interaction. Lubuk Baja sub-district has performed its role and provide maximum services, but there are still obstacles in terms of human resources, access and facilities. The importance of increasing human resources by providing training and training for the socialization, implemtation and evaluation of the policy can work well, the government should also provide easy access for the community and the addition of facilities that support the role and services to run well. Keywords: government, role, public service AbstrakStudi ini bertujuan untuk melihat bagaimana pelayanan pemrintah dalam pengurusan kartu tanda penduduk (KTP) baik itu dari aparaturnya ataupun dari peranannya. Kartu Tanda Penduduk (KTP) merupakan salah satu identitas wajib yang harus dimiliki setiap warga Negara Indonesia dan sudah diatur oleh aturan-aturan yang berlaku sehingga dalam pelaksanaannya masyarakat harus mendapatkan pelayanan yang baik. Suatu kebijakan akan berhasil dilaksanakan apabila aparatur-aparatur pemerintah dalam menjalankannya dimasyarakat sesuai dengan peranan dan aturan yang berlaku dan masyarakat juga harus menerima dan mendukung kebijakan tersebut sehingga terjadi interaksi yang baik. Kecamatan Lubuk Baja sudah menjalankan peranannya dan memberikan pelayanan yang maksimal, hanya saja masih terdapat kendala dari segi sumber daya manusia, akses dan fasilitas-fasilitas. Pentingnya peningkatan sumber daya manusia missal dengan memberikan pelatihan dan diklat agar dalam tahap sosialisasi, implemtasi dan evaluasi kebijakan dapat berjalan dengan baik, pemerintah juga harus memeberikan kemudahan akses bagi masyarakat dan penambahan-penambahan fasilitas yang mendukung peranan dan pelayanan agar berjalan dengan baik. Kata Kunci : pemerintah, peranan, pelayanan publik
Screening and Recognition of Chronic Kidney Disease in VA Health Care System Primary Care Clinics
Authors: Bansal Shweta , Mader Michael , Pugh Jacqueline A. 
Published: July 2020

Background
The successful implementation of interventions targeted to improve kidney health requires early identification of CKD which involves screening at-risk populations as well as recognizing CKD. We aim to determine CKD screening and recognition rates, factors associated with these rates, and evaluate the effect of CKD awareness on delivery of care.

Methods
A retrospective cohort study of veterans enrolled with Veterans Integrated Service Network 17 who had hypertension (HTN) and/or diabetes (DM) and were seen at least twice in primary care clinics within 18 months. The final cohort of 270,170 patients (52% HTN, 5% DM, and 44% both) was examined for serum creatinine/eGFR, urine protein/albumin, International Classification of Diseases (ICD) codes for CKD, and nephrology referral. CKD was defined as eGFR <60 ml/min per 1.73 m2 and/or urine albumin-creatinine ratio (uACR) >30 mg/g at least twice 90 days apart. Clinical covariates, HTN control, and prescription rates of renal prudent medications and nonsteroidal anti-inflammatory drugs (NSAIDs) were assessed.

Results
Overall, 254,831 (94%) patients had either eGFR, urine protein/albumin, or both. However, screening for protein/albuminuria was low (56%), particularly in patients with isolated HTN (35%). Of 254,831 patients, 92,900 (36%) had laboratory evidence of CKD and, of these, 40,586 (44%) were recognized to have CKD by ICD code and/or nephrology referral. CKD due to presence of uACR criteria alone had the lowest recognition (19%) as compared with CKD due to eGFR criteria (44%) or both (67%). Frequency of emergency room visits, hospitalization, and cardiac and endovascular procedures requiring contrast had the highest odds and races other than white had the lower odds of screening. In contrast, CKD recognition was high in races other than white and increased with worsening eGFR and increasing uACR. In screened and recognized CKD, prescription was higher for angiotensin inhibitors, statins, and diuretics, and was lower for NSAIDs.

Conclusions
Although overall CKD screening rate was high, screening of protein/albuminuria in isolated HTN and overall recognition of CKD was low in at-risk veterans. Increased recognition was associated with a favorable prescription rate for renal prudent medications.
FAKTOR DETERMINAN YANG BERHUBUNGAN DENGAN KEJADIAN ANEMIA PADA REMAJA PUTRI DI SMP LUBUKPAKAM
Authors: Nasution Zuraidah , Nurhayati Ida , Dwicahyu Ade Indah 
Published: July 2020

Berdasarkan hasil penelitian pendahuluan di Sekolah Menengah Pertama (SMP) Negeri Lubuk Pakam, remaja putri usia 13-14 tahun yang mengalami anemia terdapat sebanyak 25,7%, sedangkan pada data Kemenkes RI 2014 terdapat 18,4% remaja yang mengalami anemia. Anemia pada remaja yang sedang bersekolah akan dapat menimbulkan dampak berupa: lelah, letih dan lesu dan melemahnya aktivitas sel otak sehingga menurunkan konsentrasi dan prestasi belajar. Selanjutnya seorang remaja putri yang mengalami anemia akan menimbulkan dampak yang sangat berbahaya dan merugikan diantaranya cenderung anemia pada saat hamil, melahirkan bayi dengan berat lahir rendah, perdarahan yang dapat mengancam keselamatanbayi dan ibunya.Bayi yang lahir dengan berat badan yang rendah akan mengalami gangguan pertumbuhan metabolisme seperti IQ dibawah ambang batas normal. Kemudian bayi tersebut akan tumbuh menjadi balita anemia yang jika tidak juga di tanggulangi dan akan kembali tumbuh menjadi remaja yang defiseinsi zat besi kembali. Kondisi ini akan merugikan negara dan menghambat tujuan pembangunan nasional. Penelitian dilakukan pada remaja putri siswa di SMP Negeri LubukPakam sebanyak 116 orang. menggunakan desain crossectional. Data dikumpulkan melalui wawancara, food recall, pengukuran serta observasi, dan dianalisis menggunakan regresi logistic berganda. Tujuan penelitian untuk mengetahui faktor determinan yang berhubungan dengan kejadian anemia pada remaja putri siswa SMP Negeri Lubuk Pakam. Hasil penelitian menyimpulkan bahwa faktor yang paling dominan memengaruhi kejadian anemia pada remaja puteri SMP adalah rata-rata asupan vitamin B12 dan skor pengetahuan gizi. Asupan vitamin B12 serta pengetahuan gizi yang baik dapat masing-masing 2,04 kali dan 1,65 kali menurunkan kejadian anemia pada remaja puteri.
Homomorphisms of Sparse Signed Graphs
Authors: Charpentier Clément , Naserasr Reza , Sopena Éric 
Published: July 2020

The notion of homomorphism of signed graphs, introduced quite recently, provides better interplay with the notion of minor and is thus of high importance in graph coloring. A newer, but equivalent, definition of homomorphisms of signed graphs, proposed jointly by the second and third authors of this paper and Thomas Zaslavsky, leads to a basic no-homomorphism lemma. According to this definition, a signed graph $(G, \sigma)$ admits a homomorphism to a signed graph $(H, \pi)$ if there is a mapping $\phi$ from the vertices and edges of $G$ to the vertices and edges of $H$ (respectively) which preserves adjacencies, incidences, and signs of closed walks (i.e., the product of the sign of their edges). For $ij=00, 01, 10, 11$, let $g_{ij}(G,\sigma)$ be the length of a shortest nontrivial closed walk of $(G, \sigma)$ which is, positive and of even length for $ij=00$, positive and of odd length for $ij=01$, negative and of even length for $ij=10$, negative and of odd length for $ij=11$. For each $ij$, if there is no nontrivial closed walk of the corresponding type, we let $g_{ij}(G, \sigma)=\infty$. If $G$ is bipartite, then $g_{01}(G,\sigma)=g_{11}(G,\sigma)=\infty$. In this case, $g_{10}(G,\sigma)$ is certainly realized by a cycle of $G$, and it will be referred to as the \emph{unbalanced-girth} of $(G,\sigma)$.
It then follows that if $(G,\sigma)$ admits a homomorphism to $(H, \pi)$, then $g_{ij}(G, \sigma)\geq g_{ij}(H, \pi)$ for $ij \in \{00, 01,10,11\}$.
Studying the restriction of homomorphisms of signed graphs on sparse families, in this paper we first prove that for any given signed graph $(H, \pi)$, there exists a positive value of $\epsilon$ such that, if $G$ is a connected graph of maximum average degree less than $2+\epsilon$, and if $\sigma$ is a signature of $G$ such that $g_{ij}(G, \sigma)\geq g_{ij}(H, \pi)$ for all $ij \in \{00, 01,10,11\}$, then $(G, \sigma)$ admits a homomorphism to $(H, \pi)$.
For $(H, \pi)$ being the signed graph on $K_4$ with exactly one negative edge, we show that $\epsilon=\frac{4}{7}$ works and that this is the best possible value of $\epsilon$. For $(H, \pi)$ being the negative cycle of length $2g$, denoted $UC_{2g}$, we show that $\epsilon=\frac{1}{2g-1}$ works.
As a bipartite analogue of the Jaeger-Zhang conjecture, Naserasr, Sopena and Rollovà conjectured in [Homomorphisms of signed graphs, {\em J. Graph Theory} 79 (2015)] that every signed bipartite planar graph $(G,\sigma)$ satisfying $g_{ij}(G,\sigma)\geq 4g-2$ admits a homomorphism to $UC_{2g}$. We show that $4g-2$ cannot be strengthened, and, supporting the conjecture, we prove it for planar signed bipartite graphs $(G,\sigma)$ satisfying the weaker condition $g_{ij}(G,\sigma)\geq 8g-2$.
In the course of our work, we also provide a duality theorem to decide whether a 2-edge-colored graph admits a homomorphism to a certain class of 2-edge-colored signed graphs or not.