bluuebunny/crossref_metadata_2025_split huggingface dataset:
Open research data, an archival challenge?
Authors: Borgerud Charlotte , Borglund Erik 
Published: February 2020

AbstractThe Swedish government has decided that all research results in the form of research data and scientific publications financed with public funds should be openly accessible as far as possible. The question is whether the responsible actors and if the universities are ready to implement the change. The significance of open access has amplified in Sweden. Earlier research has brought to light that the collection and preservation of research data are often surrounded by ambiguous rules and lack a comprehensive structure. For example, archiving is not given enough consideration in connection to research projects and researchers often tend to save their material on platforms that are not persistent over time. This article is based upon a qualitative research approach where 15 semi-structured interviews have been used as primarily data sources to investigate the implementation of open access of research data and scientific publications. The article investigated how Swedish universities and public authorities were working with archiving and implementation of open research data and their opinions on open access. The results displayed a lack of coordination, resources and infrastructure but also that common agreed nomenclature were missing. The management of research data was not part of an overall recordkeeping strategy. One explanation could be differences in the information culture among researchers and archivists. Social sciences theory has been combined with archival theory in order to explain the reasons to this. These have been put in relation to the principles of the open data directive.
Degradation of the cellulosic key chromophore 2,5-dihydroxy-[1,4]-benzoquinone (DHBQ) under conditions of chlorine dioxide pulp bleaching: formation of rhodizonate as secondary chromophore—a combined experimental and theoretical study
Authors: Guggenberger Matthias , Hettegger Hubert , Zwirchmayr Nele Sophie , Hosoya Takashi , Bacher Markus , Zaccaron Sara , Böhmdorfer Stefan , Reiter Heidemarie , Spitzbart Martin , Dietz Thomas , Eibinger Klaus , Mahler Arnulf Kai , Winter Heribert , Röder Thomas , Potthast Antje , Rosenau Thomas 
Published: February 2020

Abstract
2,5-Dihydroxy-[1,4]-benzoquinone (DHBQ, 1) is the most prominent representative of cellulosic key chromophores, which occur almost ubiquitously in all types of aged cellulosics. The degradation of DHBQ by chlorine dioxide under conditions of industrial pulp bleaching (“D stage”) was studied, i.e. in moderately acidic medium (pH 3) at temperatures between 50 and 90 °C. The degradation in the presence of excess ClO2 generates rhodizonic acid (RhA, 5,6-dihydroxycyclohex-5-ene-1,2,3,4-tetrone, 2) as a secondary chromophore which is even more stable and more potent as a chromophore than the starting DHBQ, especially in the form of its salts. At least a threefold ClO2 excess is needed for complete DHBQ consumption. The reaction from DHBQ to RhA involves pentahydroxybenzene (PHB, I) as an intermediate which is either readily further oxidized to RhA by excess ClO2 or slowly reconverted to DHBQ in the absence of ClO2. The RhA yield after 30 min reaction time had a maximum of 83% at a DHBQ/ClO2 molar ratio of 1:5, and decreased with increasing ClO2 charge, reaching 38% at a DHBQ/ClO2 ratio of 1:8 and above. Degradation of DHBQ by ClO2 is 42 times faster than that of RhA (50 °C, pH 3). RhA is present in aqueous medium in the form of its dihydrate, 2,3,5,5,6,6-hexahydroxycyclohex-2-ene-1,4-dione, which contains two pairs of geminal diols at C-5 and C-6. At pH 5 and above it forms an aromatic C6O62− dianion, so that the RhA salts are very stable. These salts are intensively colored, not only the ones with transition metal cations, but also those with monovalent (Na+, K+) and especially divalent (Ca2+, Mg2+) main group metals, and usually have very low solubility so that they precipitate on the pulp fibers. It was demonstrated that the inferior ClO2-bleachability of some pulps is due to the conversion of DHBQ into colored RhA and its respective salts.

Graphic abstract
Field performance of a low-cost sensor in the monitoring of particulate matter in Santiago, Chile
Authors: Tagle Matías , Rojas Francisca , Reyes Felipe , Vásquez Yeanice , Hallgren Fredrik , Lindén Jenny , Kolev Dimitar , Watne Ågot K. , Oyola Pedro 
Published: February 2020

AbstractIntegration of low-cost air quality sensors with the internet of things (IoT) has become a feasible approach towards the development of smart cities. Several studies have assessed the performance of low-cost air quality sensors by comparing their measurements with reference instruments. We examined the performance of a low-cost IoT particulate matter (PM10 and PM2.5) sensor in the urban environment of Santiago, Chile. The prototype was assembled from a PM10–PM2.5 sensor (SDS011), a temperature and relative humidity sensor (BME280) and an IoT board (ESP8266/Node MCU). Field tests were conducted at three regulatory monitoring stations during the 2018 austral winter and spring seasons. The sensors at each site were operated in parallel with continuous reference air quality monitors (BAM 1020 and TEOM 1400) and a filter-based sampler (Partisol 2000i). Variability between sensor units (n = 7) and the correlation between the sensor and reference instruments were examined. Moderate inter-unit variability was observed between sensors for PM2.5 (normalized root-mean-square error 9–24%) and PM10 (10–37%). The correlations between the 1-h average concentrations reported by the sensors and continuous monitors were higher for PM2.5 (R2 0.47–0.86) than PM10 (0.24–0.56). The correlations (R2) between the 24-h PM2.5 averages from the sensors and reference instruments were 0.63–0.87 for continuous monitoring and 0.69–0.93 for filter-based samplers. Correlation analysis revealed that sensors tended to overestimate PM concentrations in high relative humidity (RH > 75%) and underestimate when RH was below 50%. Overall, the prototype evaluated exhibited adequate performance and may be potentially suitable for monitoring daily PM2.5 averages after correcting for RH.
Portfolio Decision Analysis for Evaluating Stakeholder Conflicts in Land Use Planning
Authors: Fasth Tobias , Bohman Samuel , Larsson Aron , Ekenberg Love , Danielson Mats 
Published: February 2020

AbstractUrban planning typically involves multiple actors and stakeholders with conflicting opinions and diverging preferences. The proposed development plans and actions greatly affect the quality of life of the local community at different spatial scales and time horizons. Consequently, it is important for decision-makers to understand and analyse the conflicting needs and priorities of the local community. This paper presents a decision analytic framework for evaluating stakeholder conflicts in urban planning. First, the stakeholders state their preferences regarding the actions in terms of a set of criteria and estimate the weight of each criterion. Then, a conflict index and overall value for each action is calculated. Next, a set of Pareto efficient portfolios of actions are generated by solving an optimization problem with different levels of conflict as a resource constraint. Finally, a sensitivity analysis of the actions is performed. The framework is demonstrated using real-world survey data collected in the municipality of Upplands Väsby, Sweden.
On the Absence of Moral Goodness in Hobbes’s Ethics
Authors: Olsthoorn Johan 
Published: February 2020

AbstractThis article reassesses Hobbes’s place in the history of ethics based on the first systematic analysis of his various classifications of formal goodness. The good was traditionally divided into three: profitably good, pleasurably good, and morally good (bonum honestum). Across his works, Hobbes replaced the last withpulchrum—a decidedly non-moral form of goodness on his account. I argue that Hobbes’s dismissal of moral goodness was informed by his hedonist conception of the good and accompanied by reinterpretations of right reason and natural law. By dispensing moral goodness and insisting on the hedonist and relational nature of the good, Hobbes moreover recast and rendered more urgent the question of why we should be moral. Hobbes is commonly thought to have raised this question so starkly because of his general insensitivity to the demands of justice. My analysis suggests that it may also, or rather, have been due to his restrictive conception of the good. A comparison with other moral philosophers from the period—including Suárez, Gassendi, Locke, and Pufendorf—indicates how unusual Hobbes’s jettisoning of moral goodness was.
The Association Between Autistic Traits and Mental Well-Being
Authors: Stimpson Nikolas J. , Hull Laura , Mandy William 
Published: February 2020

AbstractIt is now accepted that sub-clinical autistic traits are continuously distributed in the general population. It appears that there has been no prior research on the relationship between autistic traits and mental well-being. We explored the nature of such a relationship using multiple regression models. 227 non-clinical adults aged 18–50 years completed an online self-report questionnaire with measures including the Warwick-Edinburgh Mental Well-being Scale and the Broad Autism Phenotype Questionnaire (BAPQ). Of the BAPQ subscales, aloofness (social anhedonia) but not rigidity or pragmatic language problems was associated with decreased mental well-being when controlling for extraversion, neuroticism, depression, and self-reported physical health. This association was partially mediated by crisis support (the number of people a respondent felt they could turn to for help in the event of a serious personal crisis). The results suggest that aloofness is a significant negative predictor of mental well-being, and that autistic traits might not be best represented as a single unitary factor in the context of outcomes related to mental well-being. Implications pertaining to the importance of social support and the possible contributing role of low self-perceived social competence to aloofness are discussed.
On the cosimulation of multibody systems and hydraulic dynamics
Authors: Rahikainen Jarkko , González Francisco , Naya Miguel Ángel , Sopanen Jussi , Mikkola Aki 
Published: February 2020

AbstractThe simulation of mechanical devices using multibody system dynamics (MBS) algorithms frequently requires the consideration of their interaction with components of a different physical nature, such as electronics, hydraulics, or thermodynamics. An increasingly popular way to perform this task is through co-simulation, that is, assigning a tailored formulation and solver to each subsystem in the application under study and then coupling their integration processes via the discrete-time exchange of coupling variables during runtime. Co-simulation makes it possible to deal with complex engineering applications in a modular and effective way. On the other hand, subsystem coupling can be carried out in a wide variety of ways, which brings about the need to select appropriate coupling schemes and simulation options to ensure that the numerical integration remains stable and accurate. In this work, the co-simulation of hydraulically actuated mechanical systems via noniterative, Jacobi-scheme co-simulation is addressed. The effect of selecting different co-simulation configuration options and parameters on the accuracy and stability of the numerical integration was assessed by means of representative numerical examples.
Tumescent Injections in Subcutaneous Pig Tissue Disperse Fluids Volumetrically and Maintain Elevated Local Concentrations of Additives for Several Hours, Suggesting a Treatment for Drug Resistant Wounds
Authors: Koulakis John P. , Rouch Joshua , Huynh Nhan , Wu Holden H. , Dunn James C. Y. , Putterman Seth 
Published: February 2020

Abstract
Purpose
Bolus injection of fluid into subcutaneous tissue results in accumulation of fluid at the injection site. The fluid does not form a pool. Rather, the injection pressure forces the interstitial matrix to expand to accommodate the excess fluid in its volume, and the fluid becomes bound similar to that in a hydrogel. We seek to understand the properties and dynamics of externally tumesced (swollen) subcutaneous tissue as a first step in assessing whether tumescent antibiotic injections into wounds may provide a novel method of treatment.

Methods
Subcutaneous injections of saline are performed in live and dead pigs and the physical properties (volume, expansion ratio, residence time, apparent diffusion constant) of the resulting fluid deposits are observed with diffusion-weighted magnetic resonance imaging, computed tomography, and 3D scanning.

Results
Subcutaneous tissue can expand to a few times its initial volume to accommodate the injected fluid, which is dispersed thoroughly throughout the tumescent volume. The fluid spreads to peripheral unexpanded regions over the course of a few minutes, after which it remains in place for several hours. Eventually the circulation absorbs the excess fluid and the tissue returns to its original state.

Conclusions
Given the evidence for dense fluid dispersal and several-hour residence time, a procedure is proposed whereby tumescent antibiotic injections are used to treat drug-resistant skin infections and chronic wounds that extend into the subcutaneous tissue. The procedure has the potential to effectively treat otherwise untreatable wounds by keeping drug concentrations above minimum inhibitory levels for extended lengths of time.
Gene editing in plants: assessing the variables through a simplified case study
Authors: Shockey Jay 
Published: February 2020

Key message
Multiple variables that control the relative levels of successful heritable plant genome editing were addressed using simple case studies in Arabidopsis thaliana.

Abstract
The recent advent of genome editing technologies (especially CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats) has revolutionized various fields of scientific research. The process is much more specific than previous mutagenic processes and allows for targeting of nearly any gene of interest for the creation of loss-of-function mutations and many other types of editing, including gene-replacement and gene activation. However, not all CRISPR construct designs are successful, due to several factors, including differences in the strength and cell- or tissue-type specificity of the regulatory elements used to express the Cas9 (CRISPR Associated protein 9) DNA nuclease and single guide RNA components, and differences in the relative editing efficiency at different target areas within a given gene. Here we compare the levels of editing created in Arabidopsis thaliana by CRISPR constructs containing either different promoters, or altered target sites with varied levels of guanine–cytosine base content. Additionally, nuclease activity at sites targeted by imperfectly matched single guide RNAs was observed, suggesting that while the primary goal of most CRISPR construct designs is to achieve rapid, robust, heritable gene editing, the formation of unintended mutations at other genomic loci must be carefully monitored.
Response to Comment on “On the Origin of Frictional Energy Dissipation”, by B.N.J. Persson
Authors: Hu Renfeng , Krylov Sergey Yu. , Frenken Joost W. M. 
Published: February 2020

AbstractWe are grateful to Dr. B.N.J. Persson for his prompt attention to our work (Hu et al. in Tribol Lett, 10.1007/s11249-019-1247-7, 2020). In his Comment, he remarks (i) that near-critical damping of motion in/on solids, one of our main results, is well known for atoms and molecules at surfaces and (ii) that this result may be invalid for real practical cases (Persson in Tribol Lett, this issue). We fully agree with both statements. However, some discussion is justified.
Why theory matters in correctional psychology
Authors: Ward Tony 
Published: February 2020

AbstractContemporary forensic psychology is characterized by a relative lack of attention to theory building and conceptual analysis. In my view, this neglect of theory amounts to theoretical illiteracy and represents a significant obstacle to the explanation of crime and its management. In this paper I explore the problem of theoretical illiteracy for forensic psychological research and practice. First, I discuss why theory is important in science and the dangers of ignoring it. Second, I review the role of theory in addressing the myriad of practical problems facing human beings. Third, I outline three strategies to increase researchers and practitioners’ appreciation of theory construction and development: adopting a more comprehensive model of scientific method, epistemic iteration, and promoting model pluralism. Fourth, I examine two examples of core concepts from correctional psychology, that of dynamic risk factors and classification, and demonstrate how the above strategies can be used to address problems with these constructs.
Effects of adding tripterygium glycosides to angiotensin‐converting enzyme inhibitors or angiotensin receptor blockers on albuminuria in patients with diabetic nephropathy
Authors: Fang Jin‐Ying , Yang Yue , Zhang Zheng , Jiang Shi‐Min , Yu Tian‐Yu , Li Wen‐Ge 
Published: February 2020

AbstractIntroductionTripterygium glycosides (TGs) have been widely used in China to treat diabetic nephropathy (DN); however, proof of their use is scarce. The present study aimed to evaluate the effectiveness and safety of adding TGs to angiotensin‐converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs).MethodsBy searching Embase, MEDLINE, Cochrane Library, SINOMED, China National Knowledge Infrastructure, VIP Information/Chinese Scientific Journals, and WANFANG databases, we identified previous studies that met the specific selection criteria and included them in the meta‐analysis. Analyses were performed using Review Manager (version 5.3).ResultsNine randomized controlled trials were included in the final meta‐analysis. Patients were compared before and after treatment with ACE inhibitors or ARBs plus TGs, or ACE inhibitors or ARBs alone. The results revealed that treatment with ACE inhibitors or ARBs plus TGs resulted in significantly greater reductions in 24‐h urinary total protein (UTP) levels (trial duration <2 months, mean difference [MD]: −0.25; 95% confidence interval [CI]: −0.32, −0.18; trial duration between 2 and 6 months, MD: −0.39; 95% CI: −0.44, −0.33; trial duration >6 months, MD: −2.09; 95% CI: −2.89, −1.29) compared with treatment using ACE inhibitors or ARBs alone. Additionally, ACE inhibitors or ARBs plus TGs showed better results after long‐term administration. Treatment with ACE inhibitors or ARBs plus TGs resulted in significantly greater reductions in serum creatinine (SCr) compared with ACE inhibitors or ARBs alone (MD: −9.87; 95% CI: −13.76, −5.97).ConclusionIn patients with DN, adding TGs to ACE inhibitors or ARBs significantly lowered both the 24‐h UTP and SCr levels. Therefore, ACE inhibitors or ARBs plus TGs might improve the treatment of DN in patients.
The leadership role of teachers and environment club coordinators in promoting ecocentrism in secondary schools: Teachers as exemplars of environmental education
Authors: Smith William 
Published: February 2020

AbstractThis study of Naessian ecocentrism and anthropocentrism in three environment club coordinators/science teachers, their colleagues and some parents at three secondary schools uses deep ecology and relational fields as primary frameworks for open-ended interviews. The findings reveal new insights into the affective, cognitive and behavioural characteristics of coordinators who enhance environmental education in their schools. The work presents preliminary data on leadership among sustainability coordinators who run environment clubs. It fills a gap in the literature by showing that in addition to environmental educators requiring knowledge and attitudes regarding sustainability practices, affective qualities like connectedness and love for the environment may be important to their success as sustainability exemplars. Teachers emerge as sustainability exemplars in a relational field to implement sustainability across the secondary curriculum, galvanise students, teachers and parents to connect to the Earth, and help students, teachers and parents move away from anthropocentrism. Findings suggest that if schools commit resources and time to the coordinator’s role, students experience significant benefits by becoming closer to the Earth and more empowered to act for the environment in ways consistent with deep ecology.
Perceived versus actual cricothyroid membrane landmarking accuracy by emergency medicine residents and staff physicians
Authors: Schouela Nicholas , Woo Michael Y. , Pan Andy , Cheung Warren J. , Perry Jeffery J. 
Published: February 2020

ABSTRACTObjectivesCricothyrotomy is an intervention performed to salvage “can't intubate, can't ventilate” situations. Studies have shown poor accuracy with landmarking the cricothyroid membrane, particularly in female patients by surgeons and anesthesiologists. This study examines the perceived versus actual success rate of landmarking the cricothyroid membrane by resident and staff emergency physicians using obese and non-obese models.MethodsFive male and female volunteers were models. Each model was placed supine, and a point-of-care ultrasound expert landmarked the borders of each cricothyroid membrane; 20 residents and 15 staff emergency physicians were given one attempt to landmark five models. Overall accuracy and accuracy stratified by sex and obesity status were calculated.ResultsOverall landmarking accuracy amongst all participants was 58% (SD 18%). A difference in accuracy was found for obese males (88%) versus obese females (40%) (difference = 48%, 95% CI = 30–65%, p < 0.0001), and non-obese males (77%) versus non-obese females (46%) (difference = 31%, 95% CI = 12–51%, p = 0.004). There was no association between perceived difficulty and success (correlation = 0.07, 95% CI = −0.081–0.214, p = 0.37). Confidence levels overall were higher amongst staff physicians (3.0) than residents (2.7) (difference = 0.3, 95% CI = 0.1–0.6, p = 0.02), but there was no correlation between confidence in an attempt and its success (p = 0.33).ConclusionWe found that physicians demonstrate significantly lower accuracy when landmarking cricothyroid membranes of females. Emergency physicians were unable to predict their own accuracy while landmarking, which can potentially lead to increased failed attempts and a longer time to secure the airway. Improved training techniques may reduce failed attempts and improve the time to secure the airway.