bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ropivacaine vs ropivacaine with morphine after arthroscopic surgery – A study of analgesic efficacy
Authors: Jain Prithi , Shetty Kishan , M Saldanha Nichelle , Dionel Dsouza Ashton 
Published: February 2020

Multimodal anaesthesia is recommended for treatment of postoperative pain. The rationale behind this is to attain sufficient analgesia due to the synergistic and additive between various analgesics with concomitant reduction in dose of any individual drug required to attain the same effect. Therefore a combination of Ropivacaine with Morphine intra-articular was hypothesized to have better and longer postoperative analgesic effects as compared to Ropivacaine alone.Knee arthroscopies are being performed more and more often as day care surgeries under regional anaesthesia hence there is a need for suitable postoperative analgesia regimen with a long duration of action, good safety profile and which provides the ability for the patient to ambulate.This study was undertaken to compare the effects of intra-articular Ropivacaine with the effects of a combination of intra-articular Ropivacaine and Morphine. 60 patients were divided into two groups of 30 each, one receiving Ropivacaine and the other the combination of Ropivacaine and Morphine.In this study we found that post-operative pain was less in the group receiving the combination of intra-articular Ropivacaine and Morphine. The need for rescue analgesics was also found to be less in the group receiving the combination of intra-articular Ropivacaine and Morphine.
A comparison of intrathecal low dose Dexmedetomidine and clonidine as an adjuvant to bupivacaine in patients undergoing gynecological surgeries
Authors: Dave Smitul , V Bhatia Upasna , Rafikbhai Hudda Renish 
Published: February 2020

: In the anquity of post-operative analgesia, the inception of α-2 adrenergic agonist agents in subarachnoid space with adjuvance to bupivacaine has opened new chapter. The intent of the study was to compare the onset of duration of sensory and motor block, hemodynamic effects, post-operative analgesia and adverse effects of dexmedetomidine and clonidine with hyperbaric 0.5% bupivacaine for spinal anaesthesia. : Sixty adult patients received subarachnoid block either with Injection Bupivacaine (15mg) with clonidine (30µg) or Injection Bupivacaine (15mg) with Dex medetomidine (10µg). Patients were monitored for variations in heart rate and noninvasive blood pressure after the spinal anaesthesia was given till the surgery got over every 5 minutes. Both the groups were compared for onset time for sensory block, time to reach sensory block to T and T level, time of regression of sensory block by 2 dermatomes and duration of analgesia.: Mean Onset time of sensory block, time to reach T and T level was greater but not significant in Dexmedetomidine group but regression time of sensory block by 2 dermatomes was significantly higher in clonidine group, 100.21±2.58 minutes as compared to 80.43±3.45 in dexmedetomidine group. Onset time to reach bromage II was significantly faster in group BD (35.53 ±3.57seconds) as compared to Clonidine group (49.03 ± 30.15seconds). Dexmedetomidine group patients had significantly (p&#60;0.0001) higher duration of analgesia (589 ± 5.5minutes) as compared to Group clonidine (507 ± 4.8minutes). There was no sedation and no hemodynamic instability observed in either of the groups. We conclude that though both Clonidine and Dexmedetomidine prolongs duration of sensory and motor block of Bupivacaine, But Dexmedetomidine is more appropriate as it provides better VAS score (quality) and longer duration of postoperative analgesia than clonidine.
Efficacy of preoperative melatonin and ramelteon (melatonin agonist) therapy on dose requirement of propofol for induction of general anaesthesia: A comparative prospective study
Authors: Panigrahi Manas Ranjan , Roy Kuntal , Mukhopadhyay Bhabananda , Bisak Santanu , Binay Kumar  
Published: February 2020

General anesthesia is a medically induced coma with loss of protective reflexes resulting from the administration of one or more general anesthetic agents our study is to compare the role and efficacy of preoperative oral Melatonin, Ramelteon, and Midazolam therapy on the dose requirement of induction agent (Propofol). : Were divided into Case and Control Group. Case group of people were given Oral Melatonin (6mg)/Ramelteon (8mg) as premedication 2 to 3 hours before induction in OT and the control group were given oral Midazolam (5mg). After checking all the parameters, the induction process Total number of 60 people was randomly selected from ASA grade I & grade II, aged between 20 to 50 years, started with injection Propofol slowly in intravenous route and subsequently the BIS level up 60 was noted. After complete reversal of General Anesthesia, post-operative sedation level of the patient was measured using Ramsey sedation scale. Melatonin and Ramelteon shows significant reduction in preoperative anxiety state of the patient in comparison to Midazolam, measured by Hamilton Anxiety rating scale. The sedation status was measured by Ramsey Sedation Scale for each drug and it shows no significant difference between the drugs.: Considering absolute values and statistical values, all three drugs are potent premedication in general anesthesia. Among them, Melatonin is most potent in reducing the induction dose of injection Propofol. Ramelteon is also effective in reducing induction dose of Propofol. Along with, both are potent anxiolytic agent in pre-operative state.
Oświeceni latarni się nie boją. Szkic polemiczny
Authors: Skórczewski Dariusz 
Published: March 2020

Autor podejmuje polemikę z tezami Grzegorza Zająca, wyłożonymi w artykule Oświeconych nie trzeba oświecać – refleksje o szkole, powadze czytania i szaleństwie ideologii („Roczniki Humanistyczne” 67(2019), z. 1, s. 25-38). Polemika dotyczy rzekomego ideologicznego redukcjonizmu interpretacyjnego i instrumentalizacji literatury we współczesnej, postmodernistycznej nauce o literaturze ze względu na jej podatność na ideologizację. Podczas gdy G. Zając opowiada się za powrotem do lektury nastawionej na jakości estetyczne literatury jako sztuki, sytuując się na pozycji sprzed „upadku” dyskursu literaturoznawczego, autor artykułu proponuje uznanie tego „upadku” za fakt i skonfrontowanie się z krajobrazem „po upadku”. W konfrontacji tej, mającej skłonić do dyskusji nad różnymi zestawami wartości, leżącymi u podstaw poszczególnych nurtów współczesnych badań literackich, istotną rolę zdaniem autora może odegrać rozumiana po neoarystotelesowsku „Tradycja”, którą w swojej przełomowej książce Trzy antagonistyczne wersje dociekań moralnych Alasdair MacIntyre przeciwstawia modernistycznej „Encyklopedii” i postmodernistycznej „Genealogii”.
Jana Polkowskiego wiersze-rozmowy z Herbertem i Różewiczem
Authors: Kudyba Wojciech 
Published: March 2020

Poezję Jana Polkowskiego łączy z Herbertem wspólny obu poetom program poezji etycznej, charakterystyczną właśnie dla nich pasję przyświadczania podstawowym wartościom i wiarę w ocalającą moc kultury. Ciekawą grę intertekstualną, zainicjowaną przez młodszego pisarza w wierszu Przesłanie pana X, pozwala jednak niuansować ten uproszczony obraz. Od początku Przesłania pana X jest jasne, że nadzieja, której Polkowski nie odrzuca, wydaje się w jego tekście dużo bardziej problematyczna niż wizja zamieszkania w mitach kultury, jaka wyłania się z utworu autora Potęgi smaku. Także obraz wyraźnego antagonizmu Polkowskiego i Różewicza musi ulec weryfikacji. Polkowski jako autor Rozmów z Różewiczem daje się wciągnąć starszym kolegom po piórze właśnie do rozmowy − o poezji i jej zadaniach, zarysowując nie tylko protokół rozbieżności, ale także szukając tego, co jest mu bliskie w twórczości autora Niepokoju.
Acretismo diagnóstico prenatal mediante ultrasonido y resonancia magnética y su correlación histopatológica en Barranquilla (Colombia)
Authors: Parra-Anaya Guido , Díaz-Yunez Israel , Serrano-Montes Saray , Vergara-Quintero Felipe , De Nubbila-Lizcano Eduardo 
Published: March 2020

Introducción: el acretismo y percretismo se asocian con antecedentes de placentas previas y cesáreas anteriores, las cuales se han incrementado en nuestro medio. Por este motivo, su detección anteparto es fundamental en el propósito de disminuir el riesgo de morbimortalidad materna.Objetivo: evaluar la utilidad del ultrasonido (US) y la resonancia magnética (RM) en el diagnóstico prenatal de este trastorno adherencial placentario.Metodología: el presente es un estudio de cohorte prospectivo que incluyó a once mujeres en tercer trimestre de embarazo con antecedentes de placenta previa y cesárea anterior, a las cuales se les practicó US transabdominal y transvaginal, Doppler color y resonancia magnética, buscando signos de acretismo, los cuales fueron comparados con los hallazgos durante el parto y la histopatología.Resultados: el ultrasonido mostró una sensibilidad de 70% (IC95% 35,4-91,9). En contraste, el Doppler color y la resonancia magnética evidenciaron una sensibilidad de 90% (IC 95% 54,1-99,5).Conclusión: en pacientes con placenta previa y cesárea anterior, el US y el Doppler color surgen como una herramienta útil en la detección de acretismo placentario; sin embargo, se requieren mayores estudios para confirmar su validez diagnóstica.
Development of a Meniscal Ossicle After a Meniscal Root Repair Augmented with Bone Marrow Aspirate Concentrate
Authors: Eliasberg Claire D. , Lin Kenneth M. , Bauer Thomas W. , Rodeo Scott A. 
Published: March 2020

Case:
A 17-year-old boy had persistent knee pain 1 year after medial meniscal root repair augmented with bone marrow aspirate concentrate injection. Radiographs and magnetic resonance imaging (MRI) demonstrated an intrameniscal ossicle which was not present on MRI performed before 6 months. He underwent arthroscopic excision of the meniscal ossicle. At the 7-month follow-up, he had complete relief of his pain.

Conclusions:
It is possible that the meniscal ossicle developed because of osteoinductive cells and cytokines from the injected bone marrow or the drill hole for root repair and should be considered as a possible complication of this procedure.
Model Kurikulum Fullday School dengan Sistem Terpadu di Sekolah Dasar (SD) Islam Terpadu Cordova Samarinda
Authors: Kadi Titi 
Published: February 2020

The appearance phenomenon of Integrated Islamic Elementary School (IIES) that recently sponsored by Jaringan Sekolah Islam Terpadu (JSIT) in the middle of merger trend of Elementary schools which are lack of student is interesting to observe. One of the Integrated Islamic Elementary School in Samarinda which applied the curriculum concept with full day school system is the Integrated Islamic Elemantary School of Cordova Samarinda. Cordova itself taken from the famous University name in the Turkish reign of Usmani, which the education of Muslim was growing faster at that time. Curriculum and learning in IIES of Cordova integrate the general learning with the religion learning equally, even they also add the Islamic values into all general learning subject without decreasing the quality of learning value. The aim of this research are to observe: a) the curriculum model of full day school with integrated system in Integrated Islamic Elementary School of Cordova Samarinda, b) the curriculum development model of full day school with integrated system in Integrated Islamic Elementary School of Cordova Samarinda, c) the implementation of the curriculum model of full day school with integrated system in Integrated Islamic Elementary School of Cordova Samarinda is. This research utilizes the qualitative approach, where the data collecting technique used were observation, in depth interview, and document study. The analysis technique used was non statistic, which done by analyzing through the description of words or sentences in the form of explanation for the conclusion. In analyzing the data, the researcher used phasing which are as follows : (a) analyzing the data from all sources, (b) reducing the data, (c) arranging the data in units, (d) categorizing while conducting the coding, (e) checking the data validity. The finding of this research can be presented as follows : Curriculum model in IIES of Cordova is the integrated curriculum between KTSP, JSIT, character education, and local curriculum. Curriculum development model in IIES of Cordova Samarinda has the support of the stakeholders which called the “grass roots system” approach. The steps are (a) make the development group of KTSP in the school, (b) held the FGD between the development group and the stakeholders, (c) make the KTSP draft, (d) the school principle or the vice of curriculum need to make the validity to the school committee, and draft legalization to the education board, (e) the supervised KTSP draft has been through the process of validation and legalization, KTSP document is implementative for the school. Curriculum implementation model in IIES of Cordova Samarinda consists of the parenting integration : formal, nonformal, and informal design. Material integration : religion, general, talent and interest, also life skill. Field integration : cognitive, affective, and psychomotor. Process integration are learning and hidden curriculum.
Evaluation of Sex Hormone Levels in Benign Prostatic Hyperplasia Patients Treated with 5 Alpha-Reductase Inhibitor (Finasteride) in Amara city/Iraq
Authors: Et al. Hashim 
Published: March 2020

The present study aimed to determine the serum sex hormone levels among Benign Prostatic Hyperplasia (BPH) patients before and after 3 months of oral administration of 5-α reductase inhibitor(finasteride). Forty BPH patients and 40 healthy men from Amara city were involved in this study, their ages were between 40-59 year. They were all subjected to direct estimation of hormones by MinVidas method including Testosterone (T), Estradiol (E2), Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), Prolactin (PRL), and Dihydrotestosterone (DHT) before and after 3 months of treatment with 5α-reductase inhibitor (finasteride) (the healthy individuals didn’t take finasteride).The results showed that T level was significantly lower (P<0.05) in pre-treated compared to the post-treated patients and control group, whereas no significant difference was observed between the two latter groups. Levels of E2 - and DHT were significantly lower (P<0.01) in post-treated compared to the pre-treated patients with no significant difference with control group, while they were significantly higher (P<0.01) in pre-treated patients compared to control group. FSH and LH levels showed no significant differences in the pre-treated in comparison with post-treated and control groups. PRL levels insignificantly higher in pre-treated in comparison with post-treated patients, while significantly higher (P<0.05) in comparison with control group, with the later showing a significant lower (P<0.05) in comparison with post-treated patients. It is concluded that 5α-reductase inhibitor (finasteride) plays a role in decreasing levels of DHT and E2 which have vital roles in enlargement of prostate.
Role of Carbon Dioxide on the Corrosion of Carbon Steel Reinforcing Bar in Simulating Concrete Electrolyte
Authors: AL-Sammarraie Abdulkareem M.A. 
Published: March 2020

The main factors that make it possible to get the corrosion of reinforcing steel in concrete are chloride ions and the absorption of carbon dioxide from the environment, and each of them works with a mechanism which destroys the stable immunity of rebar in the concrete. In this work the effect of carbon dioxide content in the artificial concrete solution on the corrosion behavior of carbon steel reinforcing bar (CSRB) was studied, potentiostatically using CO2 stream gas at 6 level of concentrations; 0.03 to 2.0 weight percent, and the effect of rising electrolyte temperature was also followed in the range 20 to 50ᴼ C. Tafel plots and cyclic polarization procedures were obeyed to investigate the corrosion parameters and pitting susceptibility respectively. The change in the microstructure and morphology of the CSRB after polarization in the simulate concrete solution was studied using optical and atomic force microscopes. The results show that the corrosion rate of the CSRB in artificial concrete greatly increases with the existence of CO2 gas and highly depends on its concentration in the range 0.03 to 2.0% .No sign for pitting corrosion is recorded at all CO2 concentrations and the general corrosion is the main problem in the conditions under consideration.
Increased levels of serum Hcy and UA as well as the thickness of carotid intima-media correlates with the severity of coronary artery lesions
Authors: Tan Changming , Li Jianming , Zhou Yangzhao , Xu Feng 
Published: March 2020

Abstract
Background: To investigate the correlation between serum homocysteine (Hcy) and uric acid (UA) levels as well as the carotid intima-media thickness (IMT) and the severity of coronary artery lesions in elderly patients with coronary heart disease (CHD). Methods: A total of 156 elderly patients (≥60 years old) with CHD were recruited in the study group; 54 healthy subjects were selected as the control group. Serum Hcy and UA levels, IMT, SYNTAX score and Sullivan scores were measured and analyzed by Pearson correlation. The study group were further divided into low (≤20 points, n=72), middle (21-39 points, n=56) and high (≥40 points, n=28) score groups according to their SYNTAX score and the levels of other indexes between them were compared. The risk factors for CHD and the correlation were analyzed by univariate analysis and logistic regression. Results: SYNTAX scores showed that the levels of serum Hcy, UA, and the IMT in middle [(20.03 ± 7.88) μmol/L, (326.34 ± 79.34) μmol/L, (1.26 ± 0.07) mm)] and high score [(28.98 ± 8.04) μmol/L, (456.67 ± 98.34) μmol/L, (1.33 ± 0.08) mm] groups were significantly higher compared to the low score group [(11.34 ± 3.83) μmol/L, (206.78 ± 60.45) μmol/L, (1.19 ± 0.05) mm)], while the high score group had the highest levels (all P < 0.001). Serum Hcy, UA levels and the IMT were positively correlated with SYNTAX and Sullivan scores (all P < 0.001). Additionally, male gender, smoking, history of hypertension, systolic pressure, pulse pressure, Hcy, UA, IMT, and BMI independently correlated with the severity of CHD (all P < 0.05). Conclusions: The serum levels of Hcy and UA and the IMT in patients with CHD were significantly elevates, and positively correlated with the severity of coronary artery lesions, which may serve as diagnostic indicators.
Machine-learning (ML) reveals that Mycobacterium tuberculosis genotypes and anatomic disease site impacts drug resistance and disease transmission among patients with proven extra-pulmonary tuberculosis
Authors: Author) Doctor Busizwe Sibandze(Former Corresponding , Magazi Beki Themba , Malinga Lesibana Anthony , Maningi Nontuthuko Excellent , Shey Bong Akee , Author) Jotam G Pasipanodya(New Corresponding , Mbelle Nontombi N 
Published: March 2020

Abstract
Background
There is a general dearth of information on extrapulmonary tuberculosis (EPTB). We investigated Mycobacterium tuberculosis (Mtb) drug resistance and transmission patterns in EPTB patients treated in the Tshwane metropolitan, South Africa.
Methods
Consecutive Mtb culture-positive non-pulmonary samples from unique EPTB patients underwent further mycobacterial genotyping and were assigned to phylogenetic lineages and transmission clusters based on spoligotypes. MTBDR plus assay was used to test for isoniazid and rifampin susceptibility. ML algorithms were used to identify clinically meaningful patterns in data. We computed odds ratio (OR), attributable risk (AR) and corresponding 95% confidence intervals (CI).
Results
Of the 70 isolates examined, the largest cluster comprised of 25 (36%) Mtb strains that belonged to the East Asian lineage. East Asian lineage was significantly more likely to occur within chains of transmission when compared to the Euro-American and East-African Indian lineages: OR= 10.11 (95% CI: 1.56-116). Lymphadenitis, meningitis and skin TB, were significantly more likely to be associated with drug resistance: OR=12.69 (95% CI: 1.82-141.60) and AR = 0.25 (95% CI: 0.06-0.43) when compared with other EPTB sites, which suggests that poor rifampin penetration might be a contributing factor.
Conclusions
Majority of Mtb strains circulating in the Tshwane metropolis belongs to East Asian, Euro-American and East-African Indian lineages. Each of these are likely to be clustered, suggesting on-going EPTB transmission. Since 25% of the drug resistance was attributable to sanctuary EPTB sites notorious for poor rifampin penetration, we hypothesize that poor anti-tuberculosis drug dosing might have a role in the resistance.
Periodontal inflamed surface area in patients on haemodialysis and peritoneal dialysis: a Croatian cross-sectional study
Authors: Smojver Bojana Križan , Altabas Karmela , Knotek Mladen , Jukić Nikolina Bašić , Aurer Andrej 
Published: March 2020

Abstract
Background: The decision to initiate dialysis treatment via haemodialysis (HD) or peritoneal dialysis (PD) often involves the consideration of complex factors and remains a matter of debate. The purpose of this study was to quantify the inflammatory burden that periodontitis causes in dialysis patients and to examine whether patients on PD and HD differ in terms of the periodontal inflamed surface area (PISA), which can be helpful for selecting the most appropriate dialysis modality.
Methods: A cross-sectional study was performed on 58 consecutive patients on HD and 31 consecutive patients on PD. PISA was calculated using measurements of the clinical attachment level, recession and bleeding on probing. We performed the primary analysis using multivariable robust regression.
Results: Patients on PD had a 746 mm2 (93%) lower mean PISA than patients on HD after adjustment for 20 possible confounders, including the duration of dialysis. The type of dialysis was independently correlated with the PISA (semipartial correlation: -0.50; p=0.017; false discovery rate<5%). After adjusting for confounding factors, the correlation between the duration and type of dialysis was not significant (F (2,44)=0.01; p=0.994; η2=0.00). Differences in the PISA between patients who had undergone dialysis for less than a year, 2-3 years or ≥3 years were not significantly different in either of the two dialysis groups.
Conclusions: PISA levels in Croatian patients on dialysis indicate a high need for periodontal treatment. PD is associated with a smaller PISA independent of many sociodemographic, lifestyle, laboratory and clinical factors. The duration of dialysis does not influence PISA levels.