bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health determinants and risk factors for coronary artery disease among older Filipinos in rural communities
Authors: Cacciata Marysol C , Alvarado Irma , Jose Mini M , Evangelista Lorraine S 
Published: January 2021

AbstractAimsLifestyle modifications and healthy behavioural regimens are critical in preventing coronary artery disease (CAD) and other important health conditions. Little is known about the risk for CAD and health behaviour among older adults (&gt;60 years) living in rural areas in the Philippines. Compare risk profiles and health behaviours of Filipinos at low- vs. moderate-to-high-risk for CAD and examine the association between demographic variables, risk profiles, and health behaviours.Methods and resultsA comparative, cross-sectional study was conducted using a convenient sample of 427 Filipinos (≥60 years old). Data on sociodemographic characteristics, risk profiles, and health behaviours (e.g. diet, physical activity, smoking status, and alcohol use) were collected. Ten-year CAD risk was estimated using the non-laboratory-based Framingham algorithm. Of the 427 participants [mean age was 69.2 ± 6.7 years, primarily women (65%), married (52.8%)], 319 (75%) were at low risk, and 108 (25%) were at moderate-to-high-risk for CAD. Filipinos at moderate to high risk were more likely to have cardiometabolic diseases (e.g. hypertension, hyperlipidaemia, diabetes, and obesity, all P's &lt; 0.001). Health behaviours did not differ between the two groups except for the consumption of ≥5 servings of fruit, higher in the low-risk group.ConclusionData showed highly consistent and convergent evidence among older Filipinos living in rural areas at high risk for CAD and other health conditions. These findings underscore the need for culturally sensitive guidance to improve CAD outcomes for moderate to high-risk older adults living in rural areas, including education and counselling on risk and risk-reducing strategies.
Deep learning compound trend prediction model for hydraulic turbine time series
Authors: Xiong Lei , Liu Jiajun , Song Bo , Dang Jian , Yang Feng , Lin Haokun 
Published: January 2021

AbstractAs a clean energy with mature technology, hydropower has been widely applied in industry. The hydraulic turbine unit plays an important role in hydropower station. Since the fault of turbine unit will affect the normal operation of the whole hydropower station, this paper proposes a universal, fast and memory-efficient method trend for time-series prediction of hydraulic turbines. The proposed method adopts the expressive power of deep neural networks and the time characteristics of sequence-to-sequence structure (parallel convolution and recurrent neural network) to make time-series prediction. It also uses convolutional quantile loss and memory network to predict future extreme events. The experimental results show that the proposed method is fast, robust and accurate. It can reduce at least 34% in mean square error and 33% in convergence speed compared with the existing methods.
Probing the existence of a rich galaxy overdensity at z = 5.2
Authors: Calvi Rosa , Dannerbauer Helmut , Arrabal Haro Pablo , Rodríguez Espinosa José M , Muñoz-Tuñón Casiana , Pérez González Pablo G , Geier Stefan 
Published: January 2021

ABSTRACT
We report the results of a pilot spectroscopic program of a region at z = 5.2 in the GOODS-N field containing an overdensity of galaxies around the well-known submillimetre galaxy (SMG) HDF850.1. We have selected candidate cluster members from the optical 25 medium-band photometric catalogue of the project SHARDS (Survey for High-z Absorption Red and Dead Sources). 17 rest-frame ultraviolet (UV)-selected galaxies (LAEs and LBGs) with 5.15 &lt; zphot &lt; 5.27, candidates to be physically associated with the overdensity, have been observed with the instrument OSIRIS at the GranTeCan telescope. 13 out of these 17 (76 per cent) sources have secure spectroscopic confirmations via the Ly α line at the redshift of the galaxy protocluster PCl−HDF850.1, demonstrating the high reliability of our photometric redshift method. 10 out of 13 sources are newly confirmed members. Thus, we increase the number of confirmed members in this overdensity from 13 to 23 objects. In order to fully characterize this structure we combined our data set with the sample from the literature. Beside the SMG HDF850.1, none of the 23 spectroscopically confirmed members are bright in the far-infrared/sub-mm wavelength regime (SFRIR &lt; few hundred M⊙ yr−1). The clustering analysis of the whole sample of 23 confirmed members reveals four distinct components in physical space in different evolutionary states, within Δz &lt; 0.04 from the central region hosting SMG HDF850.1. The halo mass of the whole structure at z = 5.2, estimated by a variety of methods, range between 2 and $8\times 10^{12}\, \mathrm{M}_{\odot }$. The comparison with literature suggests a large-scale assembly comparable to the formation of a central Virgo-like cluster at z = 0 with several satellite components which will possibly be incorporated in a single halo if the protocluster is the progenitor of a more massive Coma-like cluster ($\gt 10^{15}\, \mathrm{M}_{\odot }$).
Responsibility in Cases of Structural and Personal Complicity: A Phenomenological Analysis
Authors: Knowles Charlotte 
Published: January 2021

Abstract:In cases of complicity in one’s own unfreedom and in structural injustice, it initially appears that agents are only vicariously responsible for their complicity because of the roles circumstantial and constitutive luck play in bringing about their complicity. By drawing on work from the phenomenological tradition, this paper rejects this conclusion and argues for a new responsive sense of agency and responsibility in cases of complicity. Highlighting the explanatory role of stubbornness in cases of complicity, it is argued that although agents may only be vicariously responsible for becoming complicit, they can be held more directly responsible for entrenching their complicity. The complicit agent is responsible for their complicity to the extent that they fail to take responsibility for it.
Getting to Count
Authors: Hisama Ellie M 
Published: January 2021

Abstract
The Society for Music Theory (SMT) remains a starkly male-identified society. According to the SMT’s 2019 annual report on demographics of its membership, 33% of SMT members self-identified as women—a figure that has not changed significantly over the last five years—in comparison to 51.2% of American Musicological Society members in 2017 and 52.2% of Society for Ethnomusicology members in 2014, the most recent data available. The NORC Survey of Earned Doctorates indicates that in 2018, only 20% of U.S. Ph.D.s in music theory and composition were women, a decrease from 26.4% of the period 2013–16; the previous five-year period was 18.9%. The paucity of women, trans, and non-binary gender music theorists over many decades should be a huge concern to the Society. Demographic diversity is not only an issue of equity, but also yields innovation in research that enriches the field. Drawing on insights about disciplinary constructions of gender and race by women scholars and scholars of color in classics and philosophy, experiences shared by women in music theory, an interview I conducted with composer and theorist Milton Babbitt, and the archive of music theorist and pianist Patricia Carpenter, this article proposes that we rethink what gets to count as music theory, become aware of discriminatory attitudes and behavior towards those who are not men, white, or heterosexual in the field, and take action by reshaping the field into one that supports those who wish to be part of it.
The 2021 Nucleic Acids Research database issue and the online molecular biology database collection
Authors: Rigden Daniel J , Fernández Xosé M 
Published: January 2021

Abstract
The 2021 Nucleic Acids Research database Issue contains 189 papers spanning a wide range of biological fields and investigation. It includes 89 papers reporting on new databases and 90 covering recent changes to resources previously published in the Issue. A further ten are updates on databases most recently published elsewhere. Seven new databases focus on COVID-19 and SARS-CoV-2 and many others offer resources for studying the virus. Major returning nucleic acid databases include NONCODE, Rfam and RNAcentral. Protein family and domain databases include COG, Pfam, SMART and Panther. Protein structures are covered by RCSB PDB and dispersed proteins by PED and MobiDB. In metabolism and signalling, STRING, KEGG and WikiPathways are featured, along with returning KLIFS and new DKK and KinaseMD, all focused on kinases. IMG/M and IMG/VR update in the microbial and viral genome resources section, while human and model organism genomics resources include Flybase, Ensembl and UCSC Genome Browser. Cancer studies are covered by updates from canSAR and PINA, as well as newcomers CNCdatabase and Oncovar for cancer drivers. Plant comparative genomics is catered for by updates from Gramene and GreenPhylDB. The entire Database Issue is freely available online on the Nucleic Acids Research website (https://academic.oup.com/nar). The NAR online Molecular Biology Database Collection has been substantially updated, revisiting nearly 1000 entries, adding 90 new resources and eliminating 86 obsolete databases, bringing the current total to 1641 databases. It is available at https://www.oxfordjournals.org/nar/database/c/.
BMI changes in pediatric type 1 narcolepsy under sodium oxybate treatment
Authors: Ponziani Virginia , Pizza Fabio , Zenesini Corrado , Vignatelli Luca , Pession Andrea , Plazzi Giuseppe 
Published: January 2021

Abstract
Pediatric type 1 narcolepsy (NT1) is often associated with overweight and obesity. Sodium oxybate (SO), approved for the treatment of narcolepsy with cataplexy from the age of 7 years old in the United States, has been associated with weight loss, although longitudinal pediatric studies are lacking. We report a retrospective cohort of 129 consecutive patients with a 4-year follow-up, to analyze the impact of different pharmacological treatments on body mass index (BMI) z-score. At baseline, the prevalence of obesity and overweight was 26.4% (34/129) and 29.5% (38/129), respectively. Patients were divided into three groups: children treated with SO alone (group 1), with SO-combined therapy (group 2), and without SO (group 3). At the end of the first year of follow-up, group 1 and group 2 showed a significant BMI z-score reduction compared to baseline: from 1.2 ± 1.1 to 0.4 ± 1.4 for group 1 (p &lt; 0.001), and from 1.4 ± 1.1 to 1 ± 1.3 for group 2 (p = 0.002), independently from baseline clinical features. In the second year, only group 2 experienced a further and significant BMI z-score decrease (from 1.0 ± 1.2 to 0.6 ± 1.2, p = 0.037). No further significant BMI z-score changes were observed in SO-treated patients in the following years. Instead, children treated without SO developed a significant weight increase between the second and third year of therapy (BMI z-score from 0.3 ± 0.9 to 0.5 ± 0.9). In conclusion, SO treatment in pediatric NT1 is associated with a favorable weight reduction in the first year of treatment.
Multi-seasonal water-stress memory versus temperature-driven dynamic structural changes in grapevine
Authors: Shtein Ilana , Wolberg Shunamit , Munitz Sarel , Zait Yotam , Rosenzweig Tovit , Grünzweig José M , Ohana-Levi Noa , Netzer Yishai 
Published: January 2021

AbstractPerennial plants perpetually adapt to environmental changes in complex and yet insufficiently understood manner. We aimed to separate the intra-seasonal temperature effects on structure and function from perennial and annual water stress effects. This study focused on grapevine (Vitis vinifera L. ‘Cabernet Sauvignon’) petioles, which being a continuously produced organ, represent the current status of the plant. Field-grown mature plants subjected to multi-annual irrigation treatments (severe water stress, mild water stress and non-stressed) throughout the growing season were compared with greenhouse-grown plants under three temperature regimes (22, 28 and 34 °C). Physiological and functional anatomy parameters were measured. A generalized additive model (GAM) based on meteorological and lysimeter-based field data was applied to determine the relative influence of various meteorological parameters on evapotranspiration (ETc) during the growing season in the field experiment.At the beginning of the growing season, in May, petioles in the severe stress treatment showed a stress-related structure (decreased length, safer hydraulic structure and increased lignification), though having high values of stem water potential (SWP). As the season progressed and temperatures increased, all water availability treatments petioles showed similar changes, and at the end of season, in August, were structurally very similar. Those changes were independent of SWP and were comparable to high temperature-induced changes in the greenhouse. In contrast, stems hydraulic structure was strongly influenced by water availability. Regression analyses indicated a relationship between petioles xylem structure and stomatal conductance (gs), whereas gs (but not SWP) was temperature-dependent. The GAM showed that ETc was mainly dependent on temperature.Our results indicate a perennial water-stress memory response, influencing the petiole structure at the beginning of the following season. Intra-seasonally, the petiole's structure becomes independent of water status, whereas temperature drives the structural changes. Thus, ongoing climate change might disrupt plant performance by purely temperature-induced effects.
MACULAR SENSITIVITY IN THE AREA OF INTERNAL LIMITING MEMBRANE PEELING IN EYES AFTER PARS PLANA VITRECTOMY WITH THE TEMPORAL INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE FOR A FULL-THICKNESS MACULAR HOLE
Authors: Kaluzny Jakub J. , Zabel Przemysław , Kaluzna Martyna , Lamkowski Aleksander , Jaworski Damian , Woznicki Krzysztof , Zabel Katarzyna 
Published: January 2021

Purpose:
To examine the relationship between retinal sensitivity and the area of internal limiting membrane (ILM) peeling during pars plana vitrectomy for a full-thickness macular hole.

Methods:
Twenty-four eyes a minimum of 6 months after temporal inverted flap pars plana vitrectomy for a full-thickness macular hole were included in the study. En face spectral-domain optical coherence tomography images were used to assess margins of the peeled ILM area. Microperimetry was performed to examine retinal sensitivity within the central 10°. Areas of peeled ILM in en face optical coherence tomography images were correlated with the average sensitivity threshold. Retinal sensitivities at the location of each measurement point were compared with structural abnormalities observed in en face spectral-domain optical coherence tomography images.

Results:
The mean retinal sensitivity in the area of ILM removal was significantly lower compared with the area of preserved ILM (24.29 ± 3.96 dB vs. 26.19 ± 2.10 dB, P < 0.0001, respectively). The peeled ILM area showed a negative correlation with the average sensitivity threshold (r = −0.56, P < 0.01).

Conclusion:
A larger area of ILM peeling during temporal inverted flap pars plana vitrectomy for a full-thickness macular hole is related to lower retinal sensitivity in the central macula.
THE INCIDENCE, CHARACTERISTICS, MANAGEMENT, PROGNOSIS, AND CLASSIFICATION OF BREAKTHROUGH VITREOUS HEMORRHAGE SECONDARY TO POLYPOIDAL CHOROIDAL VASCULOPATHY
Authors: Zhao Xin-Yu , Luo Ming-Yue , Meng Li-Hui , Zhang Wen-Fei , Li Bing , Wang Er-Qian , Liu Sheng-Zhi , Yu Wei-Hong , Chen You-Xin 
Published: January 2021

Purpose:
To describe breakthrough vitreous hemorrhage secondary to polypoidal choroidal vasculopathy (PCV).

Methods:
Patients with the diagnosis of PCV from January 2005 to March 2020 at Peking Union Medical College Hospital were retrospectively reviewed, cases with breakthrough vitreous hemorrhage were analyzed. Subgroup analysis was conducted regarding pachychoroid PCV and nonpachychoroid PCV.

Results:
Among 722 PCV patients (834 eyes), 103 eyes with breakthrough vitreous hemorrhage (12.4%) were included. Pars plana vitrectomy and proper further interventions could significantly improve the best-corrected visual acuity from logMAR 2.15 ± 0.48 (Snellen 20/2825) to 1.65 ± 0.67 (20/893). Hemorrhagic retinal detachment, baseline central macular thickness, and best-corrected visual acuity were factors associated with final best-corrected visual acuity (P < 0.05). In the pachychoroid PCV group, patients were younger, all had hemorrhagic pigment epithelial detachment, with a higher prevalence of choroidal vascular hyperpermeability and hemorrhagic retinal detachment, thicker subfoveal choroidal thickness, and thinner central macular thickness; besides, the initial pars plana vitrectomy were more complicated, more additional surgeries had to be performed. More eyes in the nonpachychoroid PCV group had received anti–vascular endothelial growth factor or photodynamic therapy, mostly fibrovascular pigment epithelial detachment, the best-corrected visual acuity and the status of the fellow eye were significantly worse. For the final ocular status, more eyes in nonpachychoroid PCV group were taking anti–vascular endothelial growth factor monotherapy, whereas more eyes in pachychoroid PCV group were stable. The choroidal parameters of these two groups were all significantly different.

Conclusion:
Breakthrough vitreous hemorrhage is a troublesome complication of PCV. Pars plana vitrectomy and additional interventions are required for better prognosis. Vitreous hemorrhage secondary to pachychoroid PCV or nonpachychoroid PCV have different characteristics and prognosis.
Cervical Cancer Prevention: Screening Among Undocumented Hispanic Women Compared With Documented Hispanic Women
Authors: Mehta Naaman , Raker Christina , Robison Katina 
Published: January 2021

Objective
This study compared cervical cancer knowledge, screening practices, and barriers to screening among undocumented and documented Hispanic women.

Materials and Methods
An anonymous cross-sectional survey was administered to self-identifying Hispanic women older than 21 years at community-based clinics and health care–focused community sites in Rhode Island. The survey included demographics, immigration status, questions related to cervical cancer knowledge, screening practices, and barriers to screening. Participants were stratified based on their immigration status. Categorical variables were compared by χ2 or Fisher exact test. Knowledge scores and the number of barriers were compared by t test and Wilcoxon rank sum test, respectively. p values of less than .05 were considered statistically significant.

Results
Seventy-three undocumented women and 70 documented women were enrolled. Undocumented women had a significantly lower mean cervical cancer knowledge score (3.53, SD =1.97) compared with documented women (4.43, SD = 2.04; p = .0085) and also experienced more barriers to having cervical cytology or a human papillomavirus test (p = .001). Eighty-eight percent of the undocumented women and 47% of the documented women did not have health insurance (p < .0001). Sixty-two percent of the undocumented women felt that their lack of documentation was a barrier to cervical cancer screening. Fifty percent of the undocumented and 47% of the documented women had never heard of the human papillomavirus vaccine.

Conclusions
Undocumented women have significantly lower mean cervical cancer knowledge scores compared with documented women. A lack of legal documentation is a significant barrier to cervical cancer screening among Hispanic women. Challenges inherent to being undocumented may contribute to women's lower knowledge scores and more pronounced barriers.
Lacrimal scintigraphy BNMS Guidelines
Authors: Costa Ines M. , Pereira Luisa R. , Jessop Maryam , Shawgi Mohamed , James Jackie M. , Dizdarevic Sabina ,   on behalf of the British Nuclear Medicine Society Professional Standards committee (PSC)
Published: January 2021

Purpose
The purpose of this guideline is to assist specialists in Nuclear Medicine and Radionuclide Radiology in recommending, performing, interpreting and reporting the results of lacrimal scintigraphy (also known as Dacroscintigraphy). This guideline will assist individual departments to formulate their own local protocols. This does not aim to be prescriptive regarding technical aspects of individual camera acquisitions, which need to be developed in conjunction with the local experts in medical physics. There are numerous radiological techniques to assess the physiology of the lacrimal system. This guideline will describe the application of a drop of radiotracer into each eye and consecutive imaging to demonstrate the level of impaired drainage, with the possibility of quantifying such impairment. This guideline is a recent and updated version of a previously published guideline on the British Nuclear Medicine Society website in 2018 [1].
Comparison of the diagnostic utility of 99mTc-PSMA scintigraphy versus 68Ga-PSMA-11 PET/CT in the detection of metastatic prostate cancer and dosimetry analysis: a gamma-camera-based alternate prostate-specific membrane antigen imaging modality
Authors: Singh Baljinder , Sharma Sarika , Bansal Parul , Hooda Monika , Singh Harmandeep , Parihar Ashwin Singh , Kumar Ajay , Watts Ankit , Mohan Ravi , Singh Shrawan K. 
Published: January 2021

Objective
The present study was performed for head-to-head comparison between 68Ga-prostate-specific membrane antigen (PSMA) PET/computed tomography (CT) and 99mTc-PSMA whole-body and regional single-photon emission computed tomography (SPECT)/CT for the detection of prostate cancer metastases.

Methods
Ten patients with metastatic prostate cancer underwent 99mTc-PSMA whole-body scan after intravenous injection of 230–330 MBq 99mTc-PSMA. Anterior and posterior whole-body images were acquired at 10 min, 2, 4 and/or 5/6 h post-injection. Additional SPECT/CT images were acquired for the involved sites, where planar images did not clearly identify the metastatic sites. All patients also underwent whole-body 68Ga-PSMA PET/CT and the results between the two techniques were compared for the detection of the metastatic lesions. Dosimetry analysis of the 99mTc-PSMA studies was performed using the MIRD-OLINDA approach.

Results
68Ga-PSMA PET/CT detected lesions in all 10 patients, whereas 99mTc-PSMA imaging detected lesions in 9/10 patients. 68Ga-PSMA PET/CT imaging identified a total of 112 PSMA avid metastatic lesions compared to 57 (51%) lesions on 99mTc-PSMA imaging. Eighteen out of 57 lesions were detected only on delayed 99mTc-PSMA imaging at 4 h and/or 6 h. The regional 99mTc-PSMA SPECT detected 51/83 (61.0%) lesions seen on 68Ga-PSMA PET/CT. The dosimetry results demonstrated that 99mTc-PSMA provided organs’ radiation absorbed/effective doses comparable with 99mTc-PSMA imaging.

Conclusion
Whole-body 99mTc-PSMA combined with regional SPECT/CT could be a potential alternative to 68Ga-PSMA PET for the detection of the advanced stage metastatic prostate cancer and for response evaluation to PSMA-based targeted therapies.