bluuebunny/crossref_metadata_2025_split huggingface dataset:
The lipid metabolism in carp during invasion by the tapeworn Bothriocephalus acheilognathi
Authors: Yuskiv L. L. , Yuskiv I. D. 
Published: August 2020

The changes in total lipids, their fatty acid composition and the ratio of individual classes were established in tissues of the intestine, hepatopancreas and skeletal muscles of carp (Cyprinus carpio Linnaeus, 1758), with body weight 14.5–20.5 g, at different rates of invasion by Bothriocephalus acheilognathi (Yamaguti, 1934) helminth, which belongs to the family Bothriocephalidae, of the Pseudophyllidae order, of the Cestoda class. The examined carp was divided into three groups: first group of fish was free from intestinal helminths of B. acheilognathi (control); second group of fish was weakly infected with helminths (intensity of invasion is 1–3 helminths per fish); the third group of fish was highly infected (the invasion intensity is 4 worms and more per fish). Our results showed that fish infected with helminth B. acheilognathi compared to uninfected fish had reduced total lipid level in the gut due to phospholipids, triacylglycerols, and also lipids were characterized by lower content of linoleic, linolenic, arachidonic, penta- and hexanoic fatty acids; decrease in the level of unsaturated and increase in the content of saturated fatty acids, which leads to an increase of the saturation factor. During the infection of carp with B. acheilognathi in the hepatopancreas, the content of total lipids, structural lipids – phospholipids and reserve energy sources – triacylglycerols is probably reduced, and lipids are characterized by a high content of saturated fatty acids (С14:0, С16:0, С18:0) and lower content of unsaturated: arachidonic (С20:4), linolenic (С18:3) and linoleic acid (С18:2), which is associated with a decrease in the source for the synthesis of a number of polyunsaturated fatty acids, especially docosahexaenoic (С22:6). The total content of lipids, triacylglycerols, free fatty acids and phospholipids in skeletal muscle of carp during the Bothriocephalus invasion decreased and the content of free cholesterol, mono- and triacylglycerols increased. Helminth B. acheilognathi has the effect of reducing the total lipids of the skeletal muscle content of С18-, С20-, С22-polyunsaturated fatty acids and increasing the content of saturated (С14:0, С16:0, С18:0) and monounsaturated (С16:1, С18:1) fatty acids. The obtained results prove that the parasite B. acheilognathi in the intestine of the carp significantly affects the nutrition processes of the host depending on the intensity of the damage by helminths, which is accompanied by impaired lipid metabolism.
Macronutrient status and indicators of acid-alkaline blood balance in cats with chronic renal failure
Authors: Holovakha V. I. , Mostovyi E. V. , Sliusarenko A. O. , Piddubnyak O. V. , Suslova N. I. , Matsinovich M. S. 
Published: August 2020

Chronic renal failure is a common pathology among cats. According to various literary sources, this pathology is found in 0.5–14.0% of cats. Pathology in cats in our studies is a consequence of glomerulonephritis. The diagnosis of chronic renal failure established on the basis of clinical, instrumental, and laboratory methods of blood and urine testing. Studies have found that chronic renal failure in cats is clinically characterized by apathy, anorexia, dry skin, odor of urea, vomiting, thirst, occurrence in the mouth of uremic ulcers (9.5% of patients), tachycardia (up to 177 beats per minute) tachypnoea (up to 45 respiratory movements per minute), hypertension. In the urine – hypostenuria, erythrocyturia, leukocyturia, kidney epithelium, hyaline and granular cylinders. According to echosonography – increase in echogenicity of the parenchyma, brain substance echone negative, cortico-brain differentiation erased. In the blood test – normochromic macrocytic anemia, thrombocytopenia, hyperazotemia (up to 27.9 mmol/L), hypercreatininemia (324 μmol/L), hyperuricemia (615 μmol/L), 4.6-fold increase in SDMA (symmetric dimethylargin). In chronic renal failure, cats have a significant change in the elemental composition of the blood. In particular, the Na+ content was increased by 3%, Ca2+ 1.6 times, P 2.1 times. Instead, the K+ level was reduced 1.9 times. Changes in acid-base equilibrium (ABE) were also detected: the pH decreased to 7.22; HCO3– by 34%, total CO2 by 32.3%, while anionic difference (AG) and buffer bases (BE) increased by 1.8 and 3.5 times, respectively. Such changes are characteristic of the development of lactic acidosis. The obtained experimental data on changes in mineral metabolism and acid-base equilibrium in the serum of cats in chronic renal failure supplement and clarify information on the pathogenic pathology of the kidneys in cats aged 5–10 years. Blood biochemical data can be used to improve early-stage diagnostics without clinical manifestations of chronic renal failure, their prevention and treatment, and to solve applied scientific problems in the field of nephrology and urology of small animals.
Antibacterial and fungicidal activities of ethanol extracts from Cotinus coggygria, Rhus typhina, R. trilobata, Toxicodendron orientale, Hedera helix, Aralia elata, Leptopus chinensis and Mahonia aquifolium
Authors: Zazharskyi V. V. , Davydenko P. О. , Kulishenko O. М. , Borovik I. V. , Brygadyrenko V. V. 
Published: August 2020

The search for promising plants with bactericidal and fungicidal activity is of great interest for practical and veterinary medicine, This article reveals the high antibacterial effect of the use of ethanol extracts from 8 species of plants of the families Anacardiaceae (Cotinus coggygria Scop., Rhus typhina L., Rhus trilobata Nutt. and Toxicodendron orientale Greene), Araliaceae (Hedera helix Linnaeus and Aralia elata (Miq.) Seem.), Phyllanthaceae (Leptopus chinensis (Bunge) Pojark.), Berberidaceae (Mahonia aquifolium (Pursh) Nutt.) against 23 strains of bacteria and one strain of fungi. The in vitro experiment revealed the zone of inhibition of growth of colonies exceeding 8 mm during the application of ethanol extracts of C. coggygria against twelve species of microorganisms (Enterococcus faecalis, Escherichia coli, Staphylococcus aureus, S. epidermidis, Bacillus cereus, Listeria ivanovi, Corynebacterium xerosis, Rhodococcus equi, Proteus vulgaris, P. mirabilis, Serratia marcescens and Candida albicans), Rhus typhina – against twelve species (E. faecalis, E. coli, S. aureus, S. epidermidis, L. ivanovi, C. xerosis, Rh. equi, P. vulgaris, Salmonella typhimurium, S. adobraco, S. marcescens and C. albicans), Rhus trilobata – against fourteen (E. faecalis, E. сoli, S. аureus, S. epidermidis, B. subtilis, B. cereus, L. ivanovi, C. xerosis, Rh. equi, P. vulgaris, P. mirabilis, Рseudomonas аeruginosa, Yersinia enterocolitica and C. albicans), Toxicodendron orientale – against eleven (E. faecalis, S. аureus, L. іnnocua, C. xerosis, Campylobacter jejuni, Rh. equi, P. vulgaris, P. mirabilis, Р. аeruginosa and C. albicans), Hedera helix – against seven (S. аureus, S. epidermidis, L. monocytogenes, C. jejuni, Rh. equi, P. vulgaris and C. albicans), Aralia elata – against nine (E. coli, S. aureus, B. cereus, C. xerosis, P. vulgaris, P. mirabilis, S. typhimurium, S. marcescens and C. albicans), Leptopus chinensis – only against four (E. coli, S. epidermidis, B. cereus and P. mirabilis) and Mahonia aquifolium – against only three species (S. epidermidis, C. jejuni and P. vulgaris). As a result of the research, the most promising for studying in future regarding in vivo antibacterial activity were determined to be C. coggygria, Rhus typhina, R. trilobata, Toxicodendron orientale and Aralia elata.
Chronic otitis media following infection by non-O1/non-O139 Vibrio cholerae: A case report and review of the literature
Authors: Van Bonn Sara M. , Schraven Sebastian P. , Schuldt Tobias , Heimesaat Markus M. , Mlynski Robert , Warnke Philipp C. 
Published: August 2020

AbstractWe report a case of a chronic mesotympanic otitis media with a smelly purulent secretion from both ears and recurrent otalgia over the last five years in a six-year-old girl after swimming in the German Baltic Sea. Besides Staphylococcus aureus a non-O1/non-O139 Vibrio cholerae strain could be isolated from patient samples. An antibiotic therapy with ciprofloxacin and ceftriaxone was administered followed by atticotomy combined with tympanoplasty. We conclude that V. cholerae should not be overlooked as a differential diagnosis to otitis infections, especially when patients present with extra-intestinal infections after contact with brackish- or saltwater aquatic environments.
Associations between symptoms of problematic smartphone, Facebook, WhatsApp, and Instagram use: An item-level exploratory graph analysis perspective
Authors: Rozgonjuk Dmitri , Sindermann Cornelia , Elhai Jon D. , Christensen Alexander P. , Montag Christian 
Published: August 2020

AbstractBackground and aimsStudies have demonstrated associations between both problematic smartphone and social networks use with everyday life adversities. However, examination of associations between problematic smartphone use (PSU) and problematic use of specific social networking platforms, especially on item-level data, has received relatively little attention. Therefore, the aim of the current study was to explore how items of problematic smartphone, Facebook, WhatsApp, and Instagram use are associated.Methods949 German-speaking adults participated in a web survey study. The participants were queried about their socio-demographics as well as levels of problematic smartphone, Facebook, WhatsApp, and Instagram use. In addition to bivariate correlation analysis, exploratory graph analysis (EGA), a type of network analysis, was conducted.ResultsThe results showed that while problematic Facebook and Instagram use seem to be distinct phenomena, problematic smartphone and WhatsApp use were heavily intertwined. Furthermore, the only cross-platform symptom observed was the extent of reported pain in wrists and neck due to digital technology use. The EGA network models showed very good stability in bootstrap analyses.Discussion and conclusionsIn general, the results of this study suggest that while Instagram and Facebook use may potentially constitute distinct problematic behaviors, problematic smartphone/WhatsApp use scales may be measuring highly similar or even the same construct.
Modelo de transferencia por procesos propuesto por Margarita Amestoy de Sánchez para desarrollar la habilidad de observación
Authors: Hernandez Maldonado Elpidia Maria 
Published: August 2020

El presente artículo ilustra un ejercicio de carácter cognitivo cuya finalidad es la de implementar el Modelo de Transferencia por Procesos, propuesto por la doctora Margarita Amestoy de Sánchez, con el objetivo de desarrollar la habilidad de observación en diferentes contextos. Esto se logró gracias a la adquisición de los fundamentos teóricos del modelo, el diseño y la aplicación de talleres que parten de un nivel de desarrollo básico de observación, hasta llegar a un nivel de mayor complejidad. Para realizar el diseño de los mismos, se tomaron insumos de los diferentes procesos del modelo y se asumieron como subprocesos, siendo cada uno de ellos un indicador del nivel de desarrollo de la destreza por taller. De acuerdo con la experiencia y la praxis obtenida durante la implementación, se concluye que con el MTP (Modelo de transferencia por procesos) se desarrolló la habilidad básica de observación.
Influencia de la tecnología en el aprendizaje del estudiante para resolver problemas matemáticos
Authors: Lizarazo Gómez Carlos Wilson 
Published: August 2020

Este artículo fue escrito como una contribución didáctica para los estudiantes del curso de razonamiento cuantitativo de la Universidad del Atlántico y el Cinvestav IPN de la ciudad de México, para la utilización de herramientas tecnológicas tales como los Software de geometría dinámica los cuales potencian las competencias de los estudiantes en cada uno de los pensamientos que desarrollan en la asignatura de razonamiento cuantitativo. Son las primeras pruebas implementadas en el aprendizaje del área matemática en dichas instituciones, en la que participaron estudiantes de primer semestre de humanidades y música de la facultad de Educación. Sus edades fluctuaban entre los 17 y 20 años. En el periodo de la experimentación todos estaban cursando la asignatura de razonamiento cuantitativo. A nivel de esta investigación descriptiva, se explorar el aprendizaje para solución de problemas del álgebra con Cabrí y los tres niveles de aprendizaje propuestos por Pluvinage.
Integración de las universidades de frontera de los departamentos de Guajira y Cesar de Colombia, y del Estado Zulia de Venezuela.
Authors: Espinoza Rodriguez Rafael Lenin 
Published: August 2020

La inexistencia de una real integración de las regiones de frontera venezolana y colombiana, y en consecuencia la falta de políticas y estrategias institucionales para soportar las relaciones entre universidades de frontera, mediante alianzas formales, constituye la razón de la investigación. El estudio se propone, desde su línea central de argumentación teórica, establecer los significados culturales de la integración y su correlación con los procesos de integración de las universidades localizadas en regiones interfronterizas, y diagnosticar los niveles de viabilidad y factibilidad para la creación una estructura de integración interuniversitaria, que conlleve a la transferencia de conocimiento, innovación y desarrollos tecnológicos. Para tal fin, con el fundamento de enfoques analíticos, explicativos e interpretativos se realizó la investigación Descriptiva-Explicativa; orientadas en secuencia lógica desde la construcción de un sistema teórico que es la base del diagnóstico de campo realizado a partir de tres universidades interfronterizas. Los resultados de la investigación permitieron evaluar las potencialidades de éxito del proceso y estrategias de integración y relacionamiento con las organizaciones universitarias de frontera de alcance internacional partiendo de la conformación de alianzas de conocimiento
Conocimiento didáctico del contenido de la enseñanza de ética y valores humanos, un estudio de caso.
Authors: Arias Sanabria Sandra Liliana 
Published: August 2020

En el presente texto se analiza la práctica de la enseñanza de la ética y valores humanos en clave del conocimiento didáctico del contenido (CDC) desde el modelo hexagonal propuesto por Park y Oliver. El estudio es de naturaleza cualitativa con diseño de estudio de caso, basado en un paradigma interpretativo mediante el análisis de contenido; como técnicas de recolección de información, se utiliza la observación no participante e instrumentos como la revisión documental, fichas de observación y matriz de análisis, al igual que la transcripción de la práctica pedagógica realizada por un docente de educación básica media del sector público en la ciudad de Tunja-Boyacá. Como resultados de este análisis se encuentra que el Conocimiento Didáctico del Contenido del docente, respecto de ética y valores humanos, está dado en clave de la autoestima como elemento integrador de dicha disciplina, articulado en un mayor porcentaje con dos de los componentes del modelo de Park y Oliver, el conocimiento de la estrategia y la orientación de la enseñanza principalmente. También se evidencia como finalidad del docente el fomento de la autoestima como habilidad para la vida. Por otra parte es importante resaltar, que de acuerdo con el CDC del docente, la ética debe estar direccionada en formar nuevos ciudadanos con capacidad de autorregularse a sí mismos, siendo la autorregulación un componente clave en la autoestima.
Arrhythmogenic right ventricular cardiomyopathy in recipients on heart transplant waiting list
Authors: Simonenko M. A. , Fedotov P. A. , Kostareva A. A. , Sazonova Yu. V. , Malikov K. N. , Bortsova M. A. , Polyakova A. P. , Berezina A. V. , Zemskov I. A. , Pervunina T. M. , Mitrofanova L. B. , Nikolaev G. V. , Gordeev M. L. , Sitnikova M. Yu. , Karpenko M. A. 
Published: August 2020

Aim. To determine the clinical features of arrhythmogenic right ventricular dysplasia (ARVD) in recipients on heart transplant waiting list (WL) and after a heart transplantation (HTx).Material and methods. From January 2010 to December 2018, we included 192 recipients in heart transplant waiting list (HTx WL) on behalf of Almazov National Medical Research Center. ARVD was diagnosed in 4 subjects (F Marcus et al. criteria, 2010). All 4 patients (female, mean age 46,5 years-old (16-54-year-old)) underwent HTx. Prior to HTx, arrhythmias (atrial fibrillation, atrial flutter) were diagnosed in 3 recipients. In patient №2, pacemaker in VVI mode was implanted due to sick sinus syndrome (SSS) and tachycardia-bradycardia syndrome and others underwent ICD implantation.Results. Survival after HTx was 30,9 (3,9-46,2) months. All recipients were treated with triple-drug immunosuppressive therapy (calcineurin inhibitors, mycophenolic acid, steroids) and induction with Basiliximab. All patients experienced high sensitivity to immunosuppressive therapy (agranulocytosis), and therefore a colony-stimulating factor was administered to all of them. After immunosuppression reduction (Tacrolimus plus Methylprednisolone) agranulocytosis did not recur.Conclusion. ARVD is a rare disease in the structure of end-stage heart failure in recipients in HTx WL. An examination of this pathology is necessary to manage patients on-time with surgical treatment (ICD, HTx). According to our results, causal variants in desmosome genes were determined in 1 from 4 patients and simultaneous presence of two unique genetic variants in the RKR2 gene were found in one. A special feature of post-HTx management was the development of agranulocytosis, which once again underlines the need for a personalized approach to the selection of the immunosuppressive therapy.
Tracheostomy from Insertion to de cannulation
Authors: Srivastava Mohit , Singh Himani , Kumar Singh Abhay , Singh Harsimrat , Ahmad Waseem 
Published: August 2020

Tracheostomy is a common surgical procedure, and is increasingly performed in the intensive care unit (ICU) as opposed to the operating room. Procedural knowledge is essential and is therefore outlined in this review. We also review several high-quality studies comparing percutaneous dilational tracheostomy and open surgical tracheostomy. The percutaneous method has a comparable, if not superior, safety profile and lower cost compared with the open surgical approach; therefore the percutaneous method is increasingly chosen. Standard and specialized varieties of tracheostomy tubes are available and the appropriate type is determined by patient anatomy and the indication for the tracheostomy. Fibre optic endoscopic evaluation of swallowing should be considered in assessment of bulbar function and tracheostomy weaning. A patient with a tracheostomy who develops respiratoryDistress during the ward weaning process should be investigated for upper airway pathology. Studies comparing early versus late tracheostomy suggest morbidity benefits that include less nosocomial pneumonia, shorter mechanical ventilation and shorter stay in the ICU. However, we discuss the questions that remain regarding the optimal timing of tracheostomy. We outline the potential acute and chronic complications of tracheostomy and their management, and we review the different tracheostomy tubes, their indications and when to remove them.
Acute otitis media with facial nerve palsy: Our experiences at a tertiary care teaching hospital of western U.P
Authors: Srivastava Mohit , Agarwal Sachin , Kumar Singh Abhay , Singh Harsimrat , Ahmad Waseem 
Published: August 2020

To assess acute otitis media with facial nerve paralysis, its prognosis, and treatment. It is a retrospective study. Thirteen patients of acute otitis media associated with facial nerve paralysis attended the outpatient department of otorhinolaryngology between May 2017 and April 2019. All patients were clinically assessed with appropriate investigations, prognosis, and treatment. Out of 13 patients, 2 were identified with complete facial paralysis and the remaining 11 patients presented with incomplete paralysis. Medical treatment including antibiotics and corticosteroids failed, while myringotomy and facial nerve decompression were done with a favourable outcome. Eleven patients recovered to grade-I (House-Brackmann) and 2 cases to grade-II (House-Brackmann). Peripheral facial nerve paralysis in acute otitis media is rare. Antibiotics and steroids yield good outcome as conservative management. In case of failure by conservative treatment, facial nerve decompression yields a favourable outcome.
Eagle syndrome- An underdiagnosed diagnosis
Authors: B Mane Santosh , S. Satav Sagarika , J Kahane Kaustubh , Adsule Ashish , Chawan Parmanand 
Published: August 2020

Eagle syndrome occurs when an elongated styloid process or calcified stylohyoid ligament causes recurrent throat pain or foreign body sensation, dysphagia, or facial pain. Diagnosis is usually made on physical examination by digital palpation of styloid process in tonsillar fossa.To study the significance of chronic throat pain and elongated styloid process. 60 patients with chronic throat pain (excluding other causes) were assessed by palpation of styloid process was recorded according to age, gender of patients. The prevalence of elongated styloid process in age groups and gender determined correlation and significance of chronic throat pain, along with palpable styloid process in tonsillar fossa and length of styloid process in tonsillar fossa and length of styloid process was determined..The maximum number of patients having chronic throat pain were between 40-49 years age group. The male to female ratio was 0.62:1. The prevalence of elongated styloid process was seen more in 50-70 years of age. There was a higher prevalence of elongated styloid process with moderate to severe pain. 76% patients with elongated styloid process had tonsillar fossa tenderness. 96.4% of patients with elongated styloid process had palpable styloid process in tonsillar fossa. There is a significant correlation between patients having chronic throat pain and elongated styloid process. X ray Skull-Towne’s view is very cost effective as a baseline radiological investigation to diagnose elongated styloid process in patients with chronic throat pain for which cause is unknown.
Relapsed EBV-negative aggressive NK cell Lymphoma of the orbit and scalp - A Case Report with review of literature
Authors: Sapkota Sulav , Priyadarshini Mona , Naik Radheshyam 
Published: August 2020

Nasal NK/T-cell lymphoma is a rare extranodal large cell lymphoma that involves the nasal cavity. In majority of cases, Epstein Barr virus is present and Immunophenotype shows CD3 and CD56 positivity. Loco-regional relapse is very common with poor prognosis. We report a case of Relapsed NK cell Lymphoma of the orbit and scalp region in a young boy with EBV negativity, CD3 negativity and clinically aggressive disease. Despite aggressive treatment, our case relapsed early and was complicated by prolonged pancytopenia, CNS involvement and patient died less than one year following diagnosis. NK cell lymphoma is an aggressive cancer with high mortality. Multidisciplinary modalities are essential to treat the NK cell lymphoma with radiotherapy, chemotherapy, newer agents, and hematopoietic stem cell transplantation.