bluuebunny/crossref_metadata_2025_split huggingface dataset:
Faking in Self‐Report Personality Scales: A Qualitative Analysis and Taxonomy of the Behaviors That Constitute Faking Strategies
Authors: Röhner Jessica , Schütz Astrid , Ziegler Matthias 
Published: December 2024

ABSTRACTFaking in self‐report personality scales (SRPSs) is not sufficiently understood. This limits its detection and prevention. Here, we introduce a taxonomy of faking behaviors that constitute faking strategies in SRPSs, reflecting the stages (comprehension, retrieval, judgment, and response) of the general response process model (GRPM). We reanalyzed data from two studies investigating the faking of high and low scores on Extraversion (E) and Need for Cognition (NFC) scales (Data Set 1; N = 305) or on an E scale (Data Set 2; N = 251). Participants were asked to explain exactly what they did to fake, and their responses (N = 533) were examined via a qualitative content analysis. The resulting taxonomy included 22 global and 13 specific behaviors that (in combination) constitute faking strategies in SRPSs. We organized the behaviors into four clusters along the stages of the GRPM. The behaviors held irrespective of the construct (E or NFC), and with two exceptions, also irrespective of the data set (Data Sets 1 or 2). Eight exceptions concerning faking direction (high or low) indicate direction‐specific differences in faking behaviors. Respondents reported using not only different faking behaviors (e.g., role‐playing, behaviors to avoid being detected) but also multiple combinations thereof. The suggested taxonomy is necessarily limited to the specified context, and, thus, additional faking behaviors are possible. To fully understand faking, further research in other contexts should be conducted to complement the taxonomy. Still, the complexity shown here explains why adequate detection and prevention of faking in SRPSs is so challenging.
Chronic administration of H2‐antagonists does not alter gastric secretory responses to histamine, or the antisecretory activity of sufotidine
Authors: Stables R. , Humphray J.M. , Reeves J. J. 
Published: December 2024

SUMMARYGastric secretory responses to histamine were investigated in anaesthetized dogs following treatment with oral ranitidine at 5 mg/kg twice daily for 358 weeks, and in isolated gastric mucosae from mice receiving sufotidine 240–280 mg. kg/day for 15 months. In neither study were there any significant differences between the acid secretory dose‐response curves to histamine in control and test animals. The anti‐secretory activity of oral sufotidine (1 mg/kg) against histamine‐induced acid secretion in the Heidenhain pouch dog was unaltered by twice daily dosing with sufotidine for 14 days. These studies on the effects of H2‐antagonists on histamine‐stimulated acid secretion found no evidence for development of direct tolerance at the parietal H2‐receptor level.
Intravenous pentagastrin can induce the illusion of ‘tolerance’ to a single dose of an H2‐blocker in man
Authors: Nwokolo C. U. , Sawyerr A. , Smith J. T. L. , Pounder R. E. 
Published: December 2024

SUMMARYIn a double‐blind study of Latin square design, twelve healthy male subjects were dosed with combinations of ranitidine 300 mg or placebo (at 08.50 hours) and intravenous pentagastrin (0.6 µg. kg/h) or 0. 9% saline (07.00–18.00 hours). Breakfast and lunch were served at 08.15 and 13.15 hours, respectively; hourly intragastric acidity and plasma gastrin concentration were measured from 08.00‐18.00 hours.During oral dosing with placebo, intravenous pentagastrin raised median 10‐h integrated intragastric acidity (315 to 615 pmol. h/L; P < 0.001) and lowered gastrin (86 to 55 mmol. h/L; P < 0.001). During oral dosing with ranitidine 300 mg, compared with intravenous saline, the pentagastrin infusion returned acidity towards normal (67 to 293 pmol. h/L; P < 0.001) and lowered gastrin (209 to 135 pmol. h/L; P < 0.001).This study demonstrates that a continuous pentagastrin infusion can overcome H2‐blockade and return intragastric acidity towards normal. Hypergastrinaemia observed during continued dosing with an H2‐blocket may be the mechanism for the development of tolerance.
Line‐field confocal optical coherence tomography coupled with artificial intelligence algorithms as tool to investigate wound healing: A prospective, randomized, single‐blinded pilot study
Authors: del Río‐Sancho Sergio , Christen‐Zaech Stephanie , Martinez David Alvarez , Pünchera Jöri , Guerrier Stéphane , Laubach Hans J. 
Published: December 2024

AbstractBackgroundAblative fractional photothermolysis serves as an excellent in vivo model for studying wound healing. The advent of non‐invasive imaging devices, such as line‐field confocal optical coherence tomography (LC‐OCT), enhances this model by enabling detailed monitoring of skin wound healing over time. Additionally, artificial intelligence (AI)‐based algorithms are revolutionizing the evaluation of clinical images by providing detailed analyses that are unfeasible manually.ObjectivesThis study aims to assess the value of combining LC‐OCT and AI for evaluating the acute wound healing process in the skin.MethodsThe forearms of participating volunteers were ablated with a CO2 laser in a fractional pattern (7.5 mJ/MTZ) (ClinicalTrials.gov identifier: NCT05614557). To induce observable wound healing differences, two different approved silicone‐based formulations were randomly assigned to two test sites, with a third site left untreated. In vivo LC‐OCT images were obtained at predefined intervals post‐laser treatment, ranging from 1 to 7 days. These images were further analysed using AI algorithms.ResultsLC‐OCT visualization allows for the characterization of the structural reorganization of the skin during wound healing. The additional integration of AI algorithms significantly enhances the evaluation of the efficacy of wound care interventions by providing a deeper understanding of how these interventions improve wound healing. This is particularly valuable for primary care providers and dermatologists, as AI algorithms have proven useful in observing, characterizing and understanding keratinocyte behaviour.ConclusionsThe combination of AI and high‐resolution imaging represents a promising tool for better understanding wound healing, evaluating the efficacy of current wound care interventions and analysing keratinocyte behaviour in detail during the wound healing process.ClinicalTrials.gov IdentifierNCT05614557.
Loop‐Mediated Isothermal Amplification Combined With Lateral‐Flow Dipstick for Detection of Centrocestus formosanus in Ornamental Fish
Authors: Sabaijai Metawee , Tejangkura Thanawan , Chontananarth Thapana 
Published: December 2024

ABSTRACTThe minute intestinal trematode Centrocestus formosanus is a major problem that can be found in the gills of various fish species. This parasite can destroy the gill structure of fish, leading to increased fish morbidity and mortality rates. In this study, loop‐mediated isothermal amplification (LAMP) based on the internal transcript spacer 1 region combined with a lateral‐flow dipstick (LAMP‐LFD) assay was used to detect C. formosanus in goldfish, Carassius auratus. The results showed that LAMP‐LFD was specific to C. formosanus and had no cross‐amplification with other co‐infecting parasite species, close related parasite species or their hosts (both intermediate host and definitive host). The limit of detection is as low as one metacercaria per gill. In testing 40 goldfish gill samples, the LAMP‐LFD method showed 100% accuracy when compared to traditional morphological identification. This method can be used as a rapid diagnostic tool for C. formosanus detection to obtain epidemiological information for monitoring, controlling, and preventing outbreaks of this parasite.
Elevated Fecal Biomarkers of Colo‐Rectal Epithelial Cell Activity in Irritable Bowel Syndrome
Authors: Venge Per , Tejera Valeria Castro , Petersson Christer , Xu Shengyuan , Larsson Anders , Simrén Magnus , Öhman Lena , Törnblom Hans 
Published: December 2024

ABSTRACTBackgroundIrritable bowel syndrome (IBS) is a common functional gastro‐intestinal disorder characterized by discomfort with constipation and/or diarrhea with unclear pathophysiology. We aimed to determine the activities of colorectal eosinophils, neutrophils and epithelial cells by biomarkers in feces reflecting these activities.MethodsFecal samples were collected from 185 patients with IBS before and after 8 weeks of placebo or mesalazine treatment and from 40 healthy subjects. Calprotectin, eosinophil derived neurotoxin (EDN), eosinophil cationic protein (ECP), human neutrophil lipocalin (HNL) (pab/765) or dimer, human phospholipase BII‐precursor (HPLBII‐P) and myeloperoxidase (MPO) were measured by ELISA. Symptom scores were evaluated by diaries.ResultsHPLBII‐P, HNL (pab/765) and EDN, proteins secreted by intestinal epithelial cells, were elevated in IBS patients as compared to healthy subjects (p < 0.0001–p = 0.008). In contrast, the neutrophil proteins calprotectin, MPO and HNL dimer were unaltered. The eosinophilic protein ECP was lower in IBS (p = 0.001). HNL (pab/765) (p = 0.01) and EDN (p = 0.004) increased in IBS patients after mesalazine treatment. Colo‐rectal mucosa showed strong staining of HPLBII‐P and western blotting of fecal extracts showed the presence of mainly monomeric, epithelial‐associated HNL.ConclusionsThe absence of signs of involvement of neutrophils and eosinophils in IBS suggests that activity of local epithelial cells rather than inflammation may be a major determinant of the disease. The measurements of EDN, HNL (pab/765), and HPLBII‐P may serve as potential fecal biomarkers in the study and monitoring of IBS.
Gamification From Below as by Form of Resistance: Algorithm Control, Precarity, and Resistance Dynamic of Indonesian Gig Workers
Authors: Novianto Arif 
Published: December 2024

ABSTRACTIn the digital gig economy, algorithms serve as primary tools for controlling workers within the labor process. One form of this control is through gamification, which aims to align labor supply with consumer demand, encourage quality service, and enforce worker discipline. This study surveyed of 662 couriers or gig workers in Gojek's Gosend Sameday service. Findings of this study show that Gosend Sameday drivers receive low pay and lack social protection. In light of these precarious conditions, Gojek builds the gamification scheme to incentivize hard work. In responding to the gamification created unilaterally by Gojek (gamification from above), many drivers rejected it. Resistance manifests in two forms: infrapolitics and collective resistance. Infrapolitics is part of the weapon of the weak, which is carried out by rejecting unsatisfactory orders, voicing complaints on social media, and exploiting loopholes in the Gojek driver application. Conversely, collective resistance was carried out with mass actions, strikes, picketing, organizing, and forming unions to build gamification from below. This study contributes to the understanding of how infrapolitics can inadvertently consent to platform capitalism hegemonic regime, suggesting that while drivers may it rejects gamification, the platform continues to influence labor dynamics. Collective resistance, on the other hand, challenges gamification from above and attempts to build gamification from below to create a fairer labor environment for platform drivers.
Genetic Mapping of the Powdery Mildew Resistance Gene Pm13 on Oat (Avena sativa) Chromosome 1D
Authors: Schurack Selma , Beuch Steffen , Cowan Sandy , Griffiths Irene , Lunzer Magdalena , Morales Laura , Tudor Sara , Buerstmayr Hermann , Howarth Catherine J. , Tinker Nicholas A. , Herrmann Matthias H. 
Published: December 2024

ABSTRACTPowdery mildew, caused by the biotrophic fungus Blumeria graminis DC. f. sp. avenae, is a widespread disease of oats, especially in the temperate regions of Western and Central Europe, and the use of resistant varieties is the most sustainable way to ensure stable yields. Therefore, the identification of robust and effective resistance to powdery mildew is of great interest for oat breedinpg. In contrast to race‐specific resistance genes, adult plant resistance (APR) is generally considered to be more durable. The oat variety ‘Firth’, as well as related varieties such as ‘Husky’ or ‘Flämingstip’, contains an unknown APR gene, which was previously located on chromosome 1D using DArT markers. The aim of this study was to confirm and refine the chromosomal location of this resistance gene, tentatively named Pm13. To this end, two independent experiments were carried out using different genetic material under natural infection conditions in the field: genome‐wide association mapping (GWAS) in a diverse set of 250 oat lines grown in 10 environments and QTL mapping in a HuskyxAVE1284 biparental population grown in three environments. Both approaches identified a QTL for powdery mildew resistance on the distal end of chromosome 1D in the hexaploid Sang oat genome. The locus explained up to 15% of the phenotypic variance in GWAS and 64% of the phenotypic variance in QTL mapping. Comparison of field data with results from laboratory leaf segment tests confirmed that Pm13 does indeed confer APR. The sequence information of the identified linked markers may allow the development of molecular markers useful for early selection of oat lines with high levels of APR.
Underappreciated Effects of Delayed Graft Function in Pediatric Kidney Transplantation
Authors: Peticca Benjamin , Khalil Ibrahim Y. , Robinson Samuel G. , Prudencio Tomas M. , Inlaw Christopher , Majeethia Heli , Di Carlo Antonio , Karhadkar Sunil S. 
Published: December 2024

ABSTRACTPurposeIn kidney transplantation (KT), delayed graft function (DGF) is associated with worse outcomes. However, it is unclear what effect DGF plays in long‐term survival compared to the impact of the various transplant, donor, and recipient risk factors associated with DGF. This study aims to determine the effect of DGF alone on long‐term survival in pediatric deceased donor kidney transplant recipients (DDKTRs).MethodsUsing a national database, 1728 pediatric patients who received a kidney transplant between 1994 and 2009 (n = 978) and 2010 and 2022 (n = 750) were identified. Cases and controls were matched by DGF status for transplant date, cold ischemia time, distance from the transplant center, HLA mismatch level, PRA, KDPI, recipient and donor age, BMI, sex assigned at birth, and ethnicity. Kaplan–Meier curves were analyzed with a log‐rank test. Pearson's chi‐squared tests were used to compare survival proportions between groups at time benchmarks.ResultsPediatric DDKTRs with DGF had worse graft (p < 0.001) and patient (p < 0.001) survival compared to non‐DGF patients in both eras. Between 1994 and 2009, graft survival rates were lower in the DGF cohort at 1 (p < 0.001), 3 (p < 0.001), 5 (p < 0.001), and 10 years (p = 0.010). Patient survival rates were lower in the DGF cohort at 1 (p = 0.017) and 5 years (p = 0.019) post‐DDKT. There was no difference in 3 (p = 0.071) and 10‐year patient survival rates (p = 0.141). Between 2010 and 2022, graft and patient survival rates were lower in the DGF cohort at 1, 3, 5, and 10 years (all p < 0.001). There was no difference in rates of retransplantation (p = 0.307 and p = 0.771) between groups for either era.ConclusionsDGF alone is associated with worse outcomes in pediatric DDKTRs. DGF should be taken seriously, especially in cases where pediatric DDKTRs do not possess known, attributable risk factors for DGF.
Change in Allocation Pattern of Pediatric Deceased Donor Kidneys Following the Implementation of a New Allocation Policy With Pediatric Priority in Korea
Authors: Lee Sanghoon , Lee Kyo Won , Park Jae Berm 
Published: December 2024

ABSTRACTBackgroundThe Organ Transplantation Act of Korea was amended to state that kidneys from deceased donors under age 19 (previously age 11) must be initially allocated to a waitlisted patient under age 19. The aim of this study was to analyze the change in allocation pattern of kidneys from pediatric donors following implementation of the new policy.MethodsData from the Korean Network for Organ Sharing database included donor and recipient information of kidney transplants from pediatric donors from October 2014 to September 2020.ResultsThere were 2958 deceased donors. One hundred and sixty‐three were under age 19 (163/2958, 5.5%). The study period was divided into two periods: Before policy change and after policy change. A total of 256 kidneys from 163 pediatric donors were allocated to waitlist patients. The proportion of kidneys allocated to recipients under age 19 was significantly higher after policy change (59/65, 90.8%) compared to before policy change (28/191, 14.7%, p < 0.01), with the increase most prominent in recipients aged 11–18 years. Mean time on the waitlist for all pediatric recipients of kidneys from pediatric deceased donors was 545.5 days before the change and 922.0 days after the change (p = 0.02). Mean time on the waitlist for recipients aged 1–10 years was not significantly different and that of recipients aged 11–18 years increased from 801.1 days to 1017.4 days.ConclusionA sharp increase in proportion of pediatric kidney recipients from pediatric donors was observed following implementation of amended allocation policy in October 2018.
Results on left–right Artin approximation for algebraic morphisms and for analytic morphisms of weakly‐finite singularity type
Authors: Kerner Dmitry 
Published: December 2024

AbstractThe classical Artin approximation (AP) reads: any formal solution of a system of (analytic, resp., algebraic) equations of implicit function type is approximated by “ordinary” solutions (i.e., analytic, resp., algebraic). Morphisms of scheme‐germs, for example, , are usually studied up to the left–right equivalence. The natural question is the left–right version of AP: when is the formal left–right equivalence of morphisms approximated by the “ordinary” (i.e., analytic, resp., algebraic) equivalence? In this case, the standard AP is not directly applicable, as the involved (functional) equations are not of implicit function type. Moreover, the naive extension does not hold in the analytic case, because of Osgood–Gabrielov–Shiota examples. The left–right version of Artin approximation (.AP) was established by M. Shiota for morphisms that are either Nash or [real‐analytic and of finite singularity type]. We establish .AP and its stronger version of Płoski (.APP) for , where are analytic/algebraic germs of schemes of any characteristic. More precisely:

.AP, .APP, the inverse AP (and its Płoski's version) hold for algebraic morphisms and for finite analytic morphisms;
.AP holds for analytic morphisms of weakly‐finite singularity type. (For we impose certain integrability condition.)
This latter class of morphisms of “weakly‐finite singularity type” (which we introduce) is of separate importance. It extends naturally the traditional class of morphisms of “finite singularity type,” while preserving their nonpathological behavior. The definition goes via the higher critical loci and higher discriminants of morphisms with singular targets. We establish basic properties of these critical loci. In particular, any map is finitely (right) determined by its higher critical loci.
Complete genome sequence of
Capnocytophaga
strain ARDL2 from human blood infection
Authors: Victorsen Alec , Ellison Aidan , Kubiak Jeffrey , Ferrieri Patricia , Thyagarajan Bharat , Hilt Evann E. 
Published: December 2024

ABSTRACT

This paper describes the genome assembly of a
Capnocytophaga
strain ARDL2 isolated from a human blood infection. The genome assembly comprised one circular chromosome with the length of 2,439,195 bp with a G+C content of 34.81%.
Generalized Epileptic Seizures in Fibrodysplasia Ossificans Progressiva Harboring a Recurrent Heterozygous Variant of the ACVR1 Gene (R206H)
Authors: Mishima Kenichi , Kitoh Hiroshi , Shiraki Anna , Sawamura Kenta , Kamiya Yasunari , Matsushita Masaki , Imagama Shiro 
Published: December 2024

Background: Fibrodysplasia ossificans progressiva (FOP) is an ultra‐rare disorder caused by heterozygous ACVR1 pathogenic variants and is characterized by both progressive heterotopic ossification of the soft tissues and congenital malformations of the great toe. In addition to pathological skeletal metamorphosis, patients with FOP experience diverse neurological symptoms such as chronic pain and involuntary movements; however, little is known about the association between FOP and epileptic seizures.Methods: We report the case of a young boy with FOP who sustained multiple major fractures due to epileptic loss of consciousness.Results: Based on generalized electroencephalographic abnormalities and the presence of myoclonic movements, the patient was diagnosed with juvenile myoclonic epilepsy. The absence of seizures was well‐controlled with valproic acid, whereas occasional abrupt myoclonic movements of the hands and feet persisted.Conclusion: This case expands our understanding of the phenotypic diversity of FOP and the functional versatility of ACVR1‐mediated bone morphogenetic protein (BMP) signaling.
Correlation Between Neutrophil–Lymphocyte Ratio and Inhospital Cardiac Events in Geriatric Patients With Hip Fractures
Authors: Yu Miaomiao , Cui Zhen , Bai Ying 
Published: December 2024

Background: The novel inflammatory biomarker known as the neutrophil–lymphocyte ratio (NLR) has shown great potential in predicting and prognosing many diseases. However, its correlation with postoperative inhospital major adverse cardiac events (MACEs) in geriatric patients with hip fractures remains unclear. This study investigated the relationship between NLR and postoperative inhospital MACEs among geriatric patients with hip fractures.Methods: We enrolled geriatric patients with hip fractures who were hospitalized in the Department of Geriatric Traumatology and Orthopedics, Beijing Jishuitan Hospital, Capital Medical University, between January 2023 and November 2023. After surgery, the patients were transferred to the intensive care unit (ICU) for postoperative monitoring and treatment. Patients were assigned to the MACE or non‐MACE group based on the occurrence of MACEs after surgery during their hospital stay. Clinical data were retrospectively analyzed.Results: In all, 216 patients were recruited into the study: 34 in the MACE group and 182 in the non‐MACE group. Univariate and multivariate analyses revealed that a medical history of stroke (odds ratio (OR) = 2.66, 95% confidence interval (CI) = 1.18–6.01; p = 0.018) and elevated preoperative NLR (OR = 1.09, 95% CI = 1.03–1.17; p = 0.005) were significant risk factors for postoperative inhospital MACEs. The area under the curve (AUC) of preoperative NLR‐predicted MACEs was 0.65 (0.55–0.75). Patients with a preoperative NLR <6.49 were less likely to experience inhospital MACEs, demonstrating a sensitivity of 61.8% and specificity of 64.8%.Conclusion: Elevated preoperative NLR is an independent risk factor for postoperative inhospital MACEs in geriatric patients with hip fractures.