bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Process Parameters on Distortion and Residual Stress in High-Pressure Die Cast AZ91D Components After Clean Blasting and Painting
Authors: Dini Hoda , Andersson Nils-Eric , Jarfors Anders E. W. 
Published: April 2020

AbstractA high-pressure die-casting process was employed to produce AZ91D components. These cast components were exposed to three different post-treatments: (1) clean blasting, (2) clean blasting and painting, and (3) painting (without clean blasting). The influence of the process parameters first phase injection speed, temperature of fixed half of the die, cooling time, and intensification pressure on distortion and residual stress of the components after each post-treatment were investigated. The results showed that intensification pressure was the most significant factor among the four parameters.
Nanoporous zirconia microspheres prepared by salt-assisted spray drying
Authors: Skovgaard M. , Gudik-Sørensen M. , Almdal K. , Ahniyaz A. 
Published: April 2020

AbstractNanoporous zirconia with high surface area and crystallinity has a wide range of industrial applications, such as in inorganic exchangers for ion exchange columns, catalyst substrates, and packing material for HPLC. Spherical particles of crystalline nanoporous zirconia are highly desired in various industries due to easy handling of the materials in a fluidized bed. Here, spray drying was adopted to produce spherical nanoporous zirconia powders in both laboratory scale and pilot plant scale. Effect of salts on spray-dried ZrO2powders and their crystallization behavior was studied. It was found that addition of salts to the zirconia precursors has a huge effect on the crystallization of nanoporous zirconia powders. These results have a great impact on the development of microspheres of nanocrystalline ZrO2and potentially open up a new opportunity to the low-cost production of porous ceramic microspheres with the salt templating method, in general.
Effective Practices and Recommendations for Drive-Through Clinic Points of Dispensing: A Systematic Review
Authors: Buck Brian Holt , Cowan Logan , Smith Lisa , Duncan Emily , Bazemore Jodi , Schwind Jessica S. 
Published: April 2020

ABSTRACTObjective:Drive-through clinics (DTCs) are a novel type of point of dispensing where participants drive to a designated location and receive prophylaxis while remaining inside their vehicle. The objective of this review was to identify effective practices and recommendations for implementing DTCs for mass prophylaxis dispensing during emergency events.Methods:A systematic review was conducted for articles covering DTCs published between 1990 and 2019. Inclusion criteria were peer-reviewed, written in English, and addressed DTCs sufficiently. Effective practices and recommendations identified in the literature were presented by theme.Results:A total of 13 articles met inclusion criteria. The themes identified were (1) optimal DTC design and planning via decision support systems and decision support tools; (2) clinic layouts, locations, and design aspects; (3) staffing, training, and DTC communication; (4) throughput time; (5) community outreach methods; (6) DTC equipment; (7) infection prevention and personal protective equipment; and (8) adverse events prevention and traffic management.Conclusions:DTCs are an essential component of emergency preparedness and must be optimally designed and implemented to successfully dispense mass prophylaxis to a community within 48 hours. The effective practices and recommendations presented can be used for the development, implementation, and improvement of DTCs for their target populations.
A New Crack Propagation Algorithm Combined with the Finite Element Method
Authors: Ramalho L.D.C. , Belinha J. , Campilho R.D.S.G. 
Published: April 2020

ABSTRACTThe prediction of crack propagation is an important engineering problem. In this work, combined with triangular plane stress finite elements, a new remeshing algorithm for crack opening problems was developed. The proposed algorithm extends the crack iteratively until a threshold maximum crack length is achieved. The crack propagation direction is calculated using the maximum tangential stress criterion. In this calculation, in order to smoothen the stress field in the vicinity of the crack tip, a weighted average of the stresses of the integration points around the crack tip is considered. The algorithm also ensures that there are always at least eight elements and nine nodes surrounding the crack tip, unless the crack tip is close to a domain boundary, in which case there can be fewer elements and nodes around the crack tip.Four benchmark tests were performed showing that this algorithm leads to accurate crack paths when compared to findings from previous research works, as long as the initial mesh is not too coarse. This algorithm also leads to regular meshes during the propagation process, with very few distorted elements, which is generally one of the main problems when calculating crack propagation with the finite element method.
A role for cognitive remediation therapy for job seekers with neuropsychiatric disorders
Authors: Wannasewok Kamonnet 
Published: April 2020

AbstractPeople with mental illness and traumatic brain injury experience difficulties in gaining and maintaining employment and have a higher unemployment rate because of their symptoms and poor social skills including cognitive impairments. Cognitive remediation is an intervention developed to improve cognitive functioning such as attention, memory, and problem-solving, by providing them with specific designed cognitive exercises. After practicing those cognitive tasks repetitively and massively, people with cognitive deficits will improve cognitive processes which lead to better cognitive performance. There is evidence supporting the benefits of cognitive remediation in improving employment-related outcome. Thus, it might have a role for job seekers with neuropsychiatric disorders and cognitive dysfunctions.
Differences in Retrospective Perceptions of Parenting Among Adolescents and Young Adults
Authors: Jámbori Szilvia , Kőrössy Judit 
Published: April 2020

Abstract
In the present study, the possible differences in parenting perceptions between young people socialised before the political changes in the socialist regime and those born after the regime change were explored. In Study 1 (2002) and Study 2 (2018), adolescents and young adults’ retrospective perceptions of parenting were examined. In the first study, the participants included 126 adolescents and 145 young adults, and there were 133 adolescents and 204 young adults in the second study. In both studies, the participants completed the Family Socialisation Questionnaire (Dalbert & Goch, 1997), which is employed to assess parenting practices retrospectively. Second order factor analyses on both occasions revealed that the age groups perceived parenting styles in a similar way. The similarities of the two age groups’ perceptions of parenting could be explained by employing the developmental niche theory, which is when the homeostatic functioning of the niche ensures relatively stable parenting styles, despite changing circumstances. On both occasions, young adults perceived parenting as more negative and restrictive. These results are discussed in detail.
Phenology and plant functional type dominance drive CO2 exchange in seminatural grasslands in the Pyrenees
Authors: Ibañez M. , Altimir N. , Ribas A. , Eugster W. , Sebastià M.-T. 
Published: April 2020

AbstractUnderstanding the mechanisms underlying net ecosystem CO2 exchange (NEE) in mountain grasslands is important to quantify their relevance in the global carbon budget. However, complex interactions between environmental variables and vegetation on NEE remain unclear; and there is a lack of empirical data, especially from the high elevations and the Mediterranean region. A chamber-based survey of CO2 exchange measurements was carried out in two climatically contrasted grasslands (montane v. subalpine) of the Pyrenees; assessing the relative contribution of phenology and environmental variables on CO2 exchange at the seasonal scale, and the influence of plant functional type dominance (grasses, forbs and legumes) on the NEE light response. Results show that phenology plays a crucial role as a CO2 exchange driver, suggesting a differential behaviour of the vegetation community depending on the environment. The subalpine grassland had a more delayed phenology compared to the montane, being more temperature than water constrained. However, temperature increased net CO2 uptake at a higher rate in the subalpine than in the montane grassland. During the peak biomass, productivity (+74%) and net CO2 uptake (NEE +48%) were higher in the subalpine grassland than in the montane grassland. The delayed phenology at the subalpine grassland reduced vegetation's sensitivity to summer dryness, and CO2 exchange fluxes were less constrained by low soil water content. The NEE light response suggested that legume dominated plots had higher net CO2 uptake per unit of biomass than grasses. Detailed information on phenology and vegetation composition is essential to understand elevation and climatic differences in CO2 exchange.
In vitro test for the evaluation of the efficacy of topical products for the control of Cochliomyia hominivorax larvae
Authors: Nogueira Sabrina Nathália Louzada , da Silva Maria Fernanda , Furtado Ricardo de Andrade , Paulino Júnior Daniel , Soares Maria Cecília , Andrade Maria Mariana Alves , Nascimento Eduardo Gilberti , Ferreira Lorena Lopes , Soares Vando Edésio , Lopes Welber Daniel Zanetti , Paranhos de Mendonça Rafael 
Published: April 2020

AbstractCochliomyia hominivorax larvae cause myiasis in animals and humans. To register a commercial product to control this dipteran is necessary to experiment on animals. The in vitro test was standardized to evaluate the larvicidal efficacy of commercial topical products. Five formulations were analysed in vitro and in vivo. For the in vitro test, a colony was formed and three replicates (n = 200) of each larval stage (L1, L2 and L3) were treated. The viability of the larvae was evaluated after 5 and 30 min, and at 1, 2, 6, 12, 24, 48, 60 and 72 h post-treatment (HPT). For the in vivo test, 30 bovines divided into six groups were castrated to achieve natural infestation with C. hominivorax. Animals in the treated groups received the product. Myiasis and efficacy were evaluated 12, 24, 36, 48, 60 and 72 HPT. Four formulations tested in the in vitro test achieved 100% efficacy at 24 HPT. In the in vivo experiment only one achieved 100% efficacy at 24 HPT. However, all products achieved the maximum efficacy by the end of study. The in vitro test developed here could be adopted to evaluate the efficacy of topical products for the control of C. hominivorax larvae.
Field to Media: applied ecomusicology in the Anthropocene
Authors: Pedelty Mark , Dirksen Rebecca , Hatfield Tara , Pang Yan , Roy Elja 
Published: April 2020

AbstractIn seeking to respond to the environmental challenges of the Anthropocene era, our research team of five scholars, including faculty and advanced graduate students, along with each of their collaborators in their respective research sites, has come together to explore the possibilities of a methodology that we call Field to Media. Field to Media involves using video production to study and amplify ecomusical responses to climate change, pollution, deforestation, and other environmental challenges. This methodology is intended as a pragmatic process that blends participant observation with participatory action research and applied or activist engagement. Specific to this project, our efforts have involved the co-creation of five different music videos to address a range of pressing environment-related matters in USA/Canada, Tanzania, Bangladesh, China, and Haiti. In this article, we consider some of the potential successes and challenges that we have each experienced in the course of producing these music videos.
The cost of music
Authors: Brennan Matt , Devine Kyle 
Published: April 2020

AbstractWhat is the cost of music in the so-called Anthropocene? We approach this question by focusing on the case of sound-recording formats. We consider the cost of recorded music through two overlapping lenses: economic cost, on the one hand, and environmental cost, on the other. The article begins by discussing how the price of records has changed from the late 19th to the 21st century and across the seven most economically significant playback formats: phonograph cylinder, gramophone disc, vinyl LP, cassette tape, compact disc, digital audio files on hard drive, and streaming from the cloud. Our case study territory is the United States, and we chart the gradual decline in the price of recorded music up to the present. We then examine the environmental and human costs of music by looking at what recordings are made out of, where those materials come from, and what happens to them when they are disposed of. Despite what rhetorics of digital dematerialisation tell us, we show that the labour conditions in the digital electronics and IT industries are as inhumane as ever, while the amount of greenhouse gases released by the US recording industry could actually be higher today than at the height of any previous format. We conclude by asking the obvious (but by no means straightforward) question: what are musicians and fans to do?
PLCE1 regulates the migration, proliferation, and differentiation of podocytes
Authors: Yu Seyoung , Choi Won-Il , Choi Yo Jun , Kim Hye-Youn , Hildebrandt Friedhelm , Gee Heon Yung 
Published: April 2020

AbstractPLCE1 encodes phospholipase C epsilon, and its mutations cause recessive nephrotic syndrome. However, the mechanisms by which PLCE1 mutations result in defects associated with glomerular function are not clear. To address this, we investigated the function of PLCE1 in podocytes called glomerular epithelial cells, where the pathogenesis of nephrotic syndrome converges. PLCE1 colocalized with Rho GTPases in glomeruli. Further, it interacted with Rho GTPases through the pleckstrin homology domain and Ras GTP-binding domains 1/2. Knockdown or knockout of PLCE1 in podocytes resulted in decreased levels of GTP-bound Rac1 and Cdc42, but not those of RhoA, and caused a reduction in cell migration. PLCE1 interacted with NCK2 but not with NCK1. Similar to the PLCE1 knockout, NCK2 knockout resulted in decreased podocyte migration. Knockout of PLCE1 reduced the EGF-induced activation of ERK and cell proliferation in podocytes, whereas knockout of NCK2 did not affect proliferation. Further, the knockout of PLCE1 also resulted in decreased expression of podocyte markers, including NEPH1, NPHS1, WT1, and SYNPO, upon differentiation, but the knockout of NCK2 did not affect the expression of these markers. Therefore, our findings demonstrate that PLCE1 regulates Rho GTPase activity and cell migration through interacting with NCK2 and that PLCE1 also plays a role in the proliferation and differentiation of podocytes, regardless of the presence of NCK2.
A role for gut microbiota in host niche differentiation
Authors: Greene Lydia K , Williams Cathy V , Junge Randall E , Mahefarisoa Karine L , Rajaonarivelo Tsiky , Rakotondrainibe Hajanirina , O’Connell Thomas M , Drea Christine M 
Published: April 2020

AbstractIf gut microbes influence host behavioral ecology in the short term, over evolutionary time, they could drive host niche differentiation. We explored this possibility by comparing the gut microbiota of Madagascar’s folivorous lemurs from Indriidae and Lepilemuridae. Occurring sympatrically in the eastern rainforest, our four, target species have different dietary specializations, including frugo-folivory (sifakas), young-leaf folivory (indri and woolly lemurs), and mature-leaf folivory (sportive lemurs). We collected fecal samples, from 2013 to 2017, and used amplicon sequencing, metagenomic sequencing, and nuclear magnetic resonance spectroscopy, respectively, to integrate analyses of gut microbiome structure and function with analysis of the colonic metabolome. The lemurs harbored species-specific microbiomes, metagenomes, and metabolomes that were tuned to their dietary specializations: Frugo-folivores had greater microbial and metagenomic diversity, and harbored generalist taxa. Mature-leaf folivores had greater individual microbiome variation, and taxa and metabolites putatively involved in cellulolysis. The consortia even differed between related, young-leaf specialists, with indri prioritizing metabolism of fiber and plant secondary compounds, and woolly lemurs prioritizing amino-acid cycling. Specialized gut microbiota and associated gastrointestinal morphologies enable folivores to variably tolerate resource fluctuation and support nutrient extraction from challenging resources (e.g., by metabolizing plant secondary compounds or recalcitrant fibers), perhaps ultimately facilitating host species’ diversity and specialized feeding ecologies.
An open-source robotic platform that enables automated monitoring of replicate biofilm cultivations using optical coherence tomography
Authors: Gierl Luisa , Stoy Kasper , Faíña Andrés , Horn Harald , Wagner Michael 
Published: April 2020

AbstractThe paper introduces a fully automated cultivation and monitoring tool to study biofilm development in replicate experiments operated in parallel. To gain a fundamental understanding of the relation between cultivation conditions and biofilm characteristics (e.g., structural, mechanical) a monitoring setup allowing for the standardization of methods is required. Optical coherence tomography (OCT) is an imaging modality ideal for biofilms since it allows for the monitoring of structure in real time. By integrating an OCT device into the open-source robotic platform EvoBot, a fully automated monitoring platform for investigating biofilm development in several flow cells at once was realized. Different positioning scenarios were tested and revealed that the positioning accuracy is within the optical resolution of the OCT. On that account, a reliable and accurate monitoring of biofilm development by means of OCT has become possible. With this robotic platform, reproducible biofilm experiments including a statistical analysis are achievable with only a small investment of operator time. Furthermore, a number of structural parameters calculated within this study confirmed the necessity to perform replicate biofilm cultivations.
Major surgery induces acute changes in measured DNA methylation associated with immune response pathways
Authors: Sadahiro Ryoichi , Knight Bridget , James Ffion , Hannon Eilis , Charity John , Daniels Ian R. , Burrage Joe , Knox Olivia , Crawford Bethany , Smart Neil J. , Mill Jonathan 
Published: April 2020

AbstractSurgery is an invasive procedure evoking acute inflammatory and immune responses that can influence risk for postoperative complications including cognitive dysfunction and delirium. Although the specific mechanisms driving these responses have not been well-characterized, they are hypothesized to involve the epigenetic regulation of gene expression. We quantified genome-wide levels of DNA methylation in peripheral blood mononuclear cells (PBMCs) longitudinally collected from a cohort of elderly patients undergoing major surgery, comparing samples collected at baseline to those collected immediately post-operatively and at discharge from hospital. We identified acute changes in measured DNA methylation at sites annotated to immune system genes, paralleling changes in serum-levels of markers including C-reactive protein (CRP) and Interleukin 6 (IL-6) measured in the same individuals. Many of the observed changes in measured DNA methylation were consistent across different types of major surgery, although there was notable heterogeneity between surgery types at certain loci. The acute changes in measured DNA methylation induced by surgery are relatively stable in the post-operative period, generally persisting until discharge from hospital. Our results highlight the dramatic alterations in gene regulation induced by invasive surgery, primarily reflecting upregulation of the immune system in response to trauma, wound healing and anaesthesia.
The trends in land surface heat fluxes over global monsoon domains and their responses to monsoon and precipitation
Authors: Zeng Jian , Zhang Qiang 
Published: April 2020

AbstractThe climatology, trends and leading modes of land surface latent heat flux (LHF) and sensible heat flux (SHF) as well as their responses to monsoon and precipitation in global land monsoon domains are presented. During the past three decades, LHF and SHF have generally undergone a rising and decreasing trend (that is, (LHF+, SHF−)), respectively, in Asian, North African, Austrian, and South American monsoon domains. Moreover, the increasing rate of LHF was higher than the decreasing rate of SHF, which causes a decreased trend in Bowen ratio. Two other dominant trend patterns, (LHF−, SHF−) and (LHF+, SHF+), are observed in South African and South American monsoon domains, respectively. The trends in LHF and SHF are closely linked to increasing global monsoon intensity and precipitation, especially for the monsoon domain that has annual precipitation lower than 1300 mm yr−1. Singular value decomposition (SVD) analyses show that monsoon strength explains 25.2% and 22.2% total covariance of LHF and SHF respectively in the first modes, and that precipitation slightly raises the percentages up to 27.8% and 24% respectively. The increasing monsoon and precipitation on one hand favor more land surface available energy being converted into LHF; on the other hand they enhance the LHF by increasing the land surface net radiation. Moreover, remarkable phase shifts in LHF and SHF are observed for monsoon domains during late-1990s, which are in phase with those of precipitation and monsoon strength. The intensifying LHF and precipitation indicate the acceleration of hydrological cycle in global terrestrial monsoon domains.
Meta-Analysis Based on Nonconvex Regularization
Authors: Zhang Hui , Li Shou-Jiang , Zhang Hai , Yang Zi-Yi , Ren Yan-Qiong , Xia Liang-Yong , Liang Yong 
Published: April 2020

AbstractThe widespread applications of high-throughput sequencing technology have produced a large number of publicly available gene expression datasets. However, due to the gene expression datasets have the characteristics of small sample size, high dimensionality and high noise, the application of biostatistics and machine learning methods to analyze gene expression data is a challenging task, such as the low reproducibility of important biomarkers in different studies. Meta-analysis is an effective approach to deal with these problems, but the current methods have some limitations. In this paper, we propose the meta-analysis based on three nonconvex regularization methods, which areL1/2regularization (meta-Half), Minimax Concave Penalty regularization (meta-MCP) and Smoothly Clipped Absolute Deviation regularization (meta-SCAD). The three nonconvex regularization methods are effective approaches for variable selection developed in recent years. Through the hierarchical decomposition of coefficients, our methods not only maintain the flexibility of variable selection and improve the efficiency of selecting important biomarkers, but also summarize and synthesize scientific evidence from multiple studies to consider the relationship between different datasets. We give the efficient algorithms and the theoretical property for our methods. Furthermore, we apply our methods to the simulation data and three publicly available lung cancer gene expression datasets, and compare the performance with state-of-the-art methods. Our methods have good performance in simulation studies, and the analysis results on the three publicly available lung cancer gene expression datasets are clinically meaningful. Our methods can also be extended to other areas where datasets are heterogeneous.