bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Anti-inflammatory Effects of Choerospondias axillaris Fruit’s Methanolic Extract in Synoviocytes and CIA Rat Model
Authors: Mann Sonia , Sharma Ankita , Sarkar Ashish , Kharb Rupsi , Malhotra Rajesh , Datta Barun , Gupta Rajinder K. , Biswas Sagarika 
Published: December 2019

Background:
Rheumatoid Arthritis (RA) is an autoimmune, systemic disease mainly affecting
joints. Presently, there is no specific treatment/ drug available for curing RA except few supportive
medicines. Therefore, the focus has been shifted to medicinal plants for the treatment of such diseases.
Choerospondias axillaris commonly known as Lupsi/Lapsi and has been reported to have several
properties for the treatment of various diseases.

Objective:
The present study has been conducted to explore the anti-inflammatory effects of Choerospondias
axillaris fruit extract on Synoviocytes (FLS) and Collagen-Induced Arthritis (CIA) rat model.

Methods:
Methanolic extract of the Choerospondias axillaris fruit was used for determining phytochemical,
antioxidant and anti-inflammatory properties. Antioxidant activity of Choerospondias axillaris
fruit was determined by free radicals scavenging assays and bioactive compounds were identified
via LC-MS/MS analysis. Anti-inflammatory effect was investigated in RA and Osteo Arthritis (OA)
primary cells and also in Collagen Induced Arthritis (CIA) rat models. Further, the medicinal properties
of anti-inflammatory bioactive compounds were supported by docking studies.

Results:
In-vitro and in-vivo studies showed significant decrease in the levels of inflammatory cytokines.
Docking analysis revealed that quercetin inhibits TNF-α having -9.1 kcal/mol binding energy
and 10.13 μM inhibitory constant. Quercetin also inhibits IL-6 having -6.6 kcal/mol binding energy
and 21.9 μM inhibitory constant.

Conclusion:
Observed results suggest that the underutilized fruit Choerospondias axillaris can be used
to reduce the inflammation of inflammatory diseases like RA.
Efficient Synthesis and Antibacterial Profile of Bis(2-hydroxynaphthalene- 1,4-dione)
Authors: Novais Juliana S. , Rosandiski Aline C. , de Carvalho Carolina M. , de Saules Silva Letícia S. , dos S. Velasco de Souza Lais C. , Santana Marcos V. , Martins Nathalia R.C. , Castro Helena C. , Ferreira Vitor F. , Gonzaga Daniel T.G. , de Resende Gabriel O. , de C. da Silva Fernando 
Published: December 2019

Background:
Antibacterial resistance is a serious public health problem infecting millions in
the global population. Currently, there are few antimicrobials on the market against resistant bacterial
infections. Therefore, there is an urgent need for new therapeutic options against these strains.

Objective:
In this study, we synthesized and evaluated ten Bis(2-hydroxynaphthalene-1,4-dione) against
Gram-positive strains, including a hospital Methicillin-resistant (MRSA), and Gram-negative strains.

Method:
The compounds were prepared by condensation of aldehydes and lawsone in the presence of
different L-aminoacids as catalysts in very good yields. The compounds were submitted to antibacterial
analysis through disk diffusion and Minimal Inhibitory Concentration (MIC) assays.

Result:
L-aminoacids have been shown to be efficient catalysts in the preparation of Bis(2-
hydroxynaphthalene-1,4-dione) from 2-hydroxy-1,4-naphthoquinones and arylaldehydes in excellent
yields of up to 96%. The evaluation of the antibacterial profile against Gram-positive strains (Enterococcus
faecalis ATCC 29212, Staphylococcus aureus ATCC 25923, S. epidermidis ATCC 12228) also
including a hospital Methicillin-resistant S. aureus (MRSA) and Gram-negative strains (Escherichia coli
ATCC 25922, Pseudomonas aeruginosa ATCC 27853 and Klebsiella pneumoniae ATCC 4352), revealed
that seven compounds showed antibacterial activity within the Clinical and Laboratory Standards
Institute (CLSI) levels mainly against P. aeruginosa ATCC 27853 (MIC 8-128 µg/mL) and MRSA
(MIC 32-128 µg/mL). In addition, the in vitro toxicity showed all derivatives with no hemolytic effects
on healthy human erythrocytes. Furthermore, the derivatives showed satisfactory theoretical absorption,
distribution, metabolism, excretion, toxicity (ADMET) parameters, and a similar profile to antibiotics
currently in use. Finally, the in silico evaluation pointed to a structure-activity relationship related to
lipophilicity for these compounds. This feature may help them in acting against Gram-negative strains,
which present a rich lipid cell wall selective for several antibiotics.

Conclusion:
Our data showed the potential of this series for exploring new and more effective antibacterial
activities in vivo against other resistant bacteria.
Influence of Electromagnetic Characteristics of Shell Materials on Motor Performance
Authors: Zheng Xinhua , Xu Yanan , Sun Junfeng 
Published: December 2019

Background:
In this paper, a two-pole 3 kW three-phase induction motor is taken as an
example to establish a two-dimensional finite element model. The correctness of the model is verified
by comparing the finite element calculation data with the experimental data.

Methods:
On this basis, the influence of electromagnetic characteristics of different shell materials
on the motor yoke saturation degree, loss, current and power factor are studied, it is determined
that the motor yoke saturation degree is the key factor affecting the power factor, current and loss
of the motor. The influence of different stator yoke thickness on the saturation degree of motor stator
yoke with the same shell material is further studied. The influences of motor stator yoke saturation
degree on motor current, loss and power factor are obtained when the stator yoke thickness is
different.

Results:
The optimum range of motor current, loss and power factor is obtained.

Conclusion:
Finally, by comparing the different shell materials to optimize the motor structure size, it
is determined that the motor stator yoke thickness can be reduced by using cast iron shell, and the motor
materials consumption can be saved to provide reference for motor optimization design.
Designing problem-based learning (PBL) model for tourism vocational education in 4.o industry
Authors: Ginaya Gede , Kanca I Nyoman , Sri Astuti Ni Nyoman 
Published: December 2019

The consequences of globalization should be anticipated and adjusted in education, especially the teaching and learning process. The revolution industry of 4.0 has caused some disruption in various aspects including education that is intended for the purpose of learning and innovation skills. The objective of this study is to improve the quality of learning by applying the literacy movement, character values as a provision for life and career skills using the PBL method in tourism vocational education. By applying the descriptive qualitative research method, the data, both primary and secondary, were collected through participant observation in three classes of different study programs in the Tourism Department, Bali State Polytechnic, interview, and literature study. The study found, so far, the implementation of PBL model in the classrooms has been effective. The essence of PBL is regarded as problem-solving activities, which is in the hierarchy of high order thinking skills (HOTS). As a result, the students while giving solutions to problems in various tourism workforce are able to master critical thinking skills, collaboration in teams/social interactions, and soft skills.
La cultura política de los futuros politólogos de la UNAM
Authors: Morales Mena Agustín , Hidalgo Lugo Brenda , Rubalcava Hernández Griselda , Llanos Olivier Jesús Guadalupe , Cuellar Mendoza Karla Daniela , Hernández Martínez Maricela , Puente Martínez Khemvirg 
Published: December 2019

<p>El presente artículo analiza los resultados de la Primera Encuesta de Cultura Política de los Estudiantes de Ciencia Política de la FCPYS (PECP), la cual rastreó durante el semestre 2018-1 los componentes cognitivos, afectivos y evaluativos, que convergen en estudiantes inscritos a nivel escolarizado de la carrera de Ciencia Política. Los hallazgos fueron analizados a la luz del contexto y de otros estudios de opinión a nivel nacional con el objetivo de resaltar puntos de encuentro y diferencias, que permitieron corroborar la diversidad de perfiles y culturas de la<br />comunidad de futuros politólogos de la UNAM</p>
Los prostituyentes en las políticas públicas mexicanas. Una historia de omisión
Authors: Luna Alfaro Ángel Christian 
Published: December 2019

<p>El presente artículo propone revisar mediante el análisis de algunas fuentes terciarias (bibliografía) las formas en que el Estado mexicano ha concebido la participación de hombres en la compra-venta de mujeres en situación de prostitución. La propuesta aún es descriptiva, esperando un análisis paulatino que aspire a conocer el tema discurrido. La pregunta es simple: ¿qué se dice sobre los varones prostituyentes en el marco de la explotación sexual femenina a<br />lo largo de la historia del Estado mexicano?</p>
Length-weight and length-length relationships of Red Scorpionfish (Scorpaena scrofa L. 1758) from Aegean Sea (Turkey)
Authors: Arslan Selin , Bostancı Derya 
Published: December 2019

In this study, the length-weight and length-length
relationships were investigated for S.
scrofa from İzmir Bay, Aegean Sea. All fish sample lengths and weights were
recorded to the nearest 0.01 cm and to 0.01 g. The measured total length values for females, males and combined sexes
were 16-30.2 cm; 17.7-28 cm and 16-30.2 cm respectively. The weight values for
females, males and combined sexes were 73.20-441 g; 89.80-378 g and 73.20-441 g
respectively. According to t test results, there were no
statistically significant differences for S.
scrofa species (P˃0.05); therefore, female and male samples were evaluated
together. The length-weight relationship equations as y=0.016x2.993(r²=0.914) for all specimens. The ‘b’ value of LWR was not significantly different from 3.0
and their growth type was isometric. Total length-standard length
relationship equations were determined as y=1.287x+0.112 (r²=0.97). This study is
helpful in providing information about length-weight and length-length
relationships and the current study can be useful to compare stocks of the
species in the different habitats.
Analisis SWOT Pelaksanaan Operasi SAR Kantor Pencarian dan Pertolongan Padang
Authors: Khairoza Anisa , Alhadi Zikri 
Published: December 2019

Abstrak
Penelitian ini bertujuan untuk menganalisis kekuatan, kelemahan, peluang dan ancaman yang dihadapi Kantor Pencarian dan Pertolongan Padang dalam melakukan Operasi SAR. Penelitian ini menggunakan metode penelitian kualitatif deskriptif. Hasil dari penelitian ini menunjukkan bahwa yang menjadi kekuatan Kantor Pencarian dan Pertolongan Padang dalam melakukan Operasi SAR adalah memiliki landasan hukum yang jelas dan sumber daya manusia yang berkualitas. Adapun kelemahan yang dihadapi adalah masih terbatasnya sarana dan prasarana disebabkan keterbatasan anggaran dana dari Pemerintah. Kemudian yang menjadi peluang adalah dengan adanya undang-undang nomor 29 tahun 2014 telah memberikan peluang untuk melakukan kerjasama dengan instansi yang memiliki potensi dalam melakukan Operasi SAR. Selanjutnya ancaman yang dihadapi adalah cuaca ekstrim dan keadaan lokasi kejadian. Adapun upaya yang dilakukan untuk mengatasi hambatan-hambatan yang dihadapi dalam melakukan Operasi SAR adalah melakukan kerjasama dengan instansi terkait sehingga dapat menutupi kelemahan-kelemahan yang ada.
Semiotik Panggilan Pasutri Pada Kalangan Remaja di Daerah Pasaman Barat
Authors: Samosir Uli Arta Meritua , Hasti Hasmira Mira 
Published: December 2019

Abstrak
Penelitian ini dilatarbelakangi oleh ketertarikan peneliti dalam melihat penggunaan panggilan pasutri di kalangan remaja yang berpacaran di daerah Pasaman Barat. Penelitian ini bertujuan untuk menjelaskan makna dari panggilan pasutri. Penelitian ini menggunakan kajian semiotik berdasarkan kajian semiotik model Charles Sanders Peirce. Teknik pemilihan informan menggunakan purposive sampling dengan jumlah informan 35 orang informan. Pengumpulan data dilakukan dengan cara observasi, wawancara dan dokumentasi yang dianalisis dengan menggunakan model triangle meaning semiotics. Hasil penelitian ini menunjukkan bahwa makna dari penggunaan panggilan pasutri di kalangan remaja yang berpacaran di Pasaman Barat yaitu ketika punya pacar, maka harus memiliki panggilan spesial. Ketika merasa rindu dan lelah harus diungkapkan dengan menggunakan panggilan pasutri agar apa yang dirasakan dapat tercurahkan. Selain itu makna panggilan pasutri yaitu panggilan pasutri dalam sebuah hubungan dapat meningkatkan keakraban atau kedekatan antara perempuan dan laki-laki yang sedang berpacaran. Dan yang terakhir makna dari panggilan pasutri yaitu ketika seseorang menggunakan panggilan pasutri pada saat berpacaran, maka hubungan mereka merupakan suatu hubungan pacaran yang serius. Selain itu penggunaan panggilan pasutri pada saat berpacaran ini juga dapat meningkatkan keseriusan dalam menjalin suatu hubungan.
Students' Conceptual Mindfulness about Learning Pronunciation at College Level
Authors: Saman Asma , Ali Muhammad Qasim , Kashif Dr. Najam Ul 
Published: December 2019

The study highlights students' conceptual mindfulness about learning pronunciation at college level. The objective of the study were; 1) to find out the usefulness of English language pronunciation among college students, 2) to highlight students' problems in the way of learning English pronunciation at college level and 3) to find out the perceptions of students toward English pronunciation competence at college level. It was a descriptive study and questionnaire was used as a research tool. All the college students in the three districts (Okara, Pakpattan & Sahiwal) were included in the population. Fifty college students took from each district through simple random sampling techniques. So, the total sample of the study was 150 college students from three districts. Data was analyzed and find the mean score value for all the statement and then marked the mean score value with Levels of opinion. The results of the study informed us that learning the pronunciation of the 2nd language is difficult but not impossible; little concentration, practice and hard work is required to learn pronunciation of English language. It is concluded that four integrated skills; reading, listening, writing and speaking should be used in the teaching learning process for pronunciation and also used the 'listen and repeat' technique should be used.
Bibliografía de filología hispánica
Authors: De Filología Hisp´ánica Nueva Revista 
Published: December 2019

Las reseñas se consignan a continuación del libro (o artículo reseñado). Cuando éste se ha descrito en una entrega anterior de la Bibliografía, se pone entre paréntesis el número de ficha correspondiente. También se hacen referencias a ediciones anteriores de una obra, a tomos anteriores de una obra en curso de publicación, etc. En estos casos, la cifra que precede al número de referencia indica el volumen de la NRFH en que figura la ficha en cuestión. Así, el "núm. 39-39695" corresponde a la ficha 39695, la cual está en el volumen 39 de la NRFH. Cuando no hay cifra inicial, ha de entenderse que el número remite a una ficha incluida en el presente fascículo.
Inflammatory reaction in patients with acquired bronchiectasis based on the interleukin 1α and interleukin 10 levels measured using the ELISA method
Authors: Lesan Andrei , Pop Carmen Monica 
Published: December 2019

Abstract
The main objective of this study was to determine the relationship between the pro- and anti-inflammatory response based on the interleukin 1α and interleukin 10 levels in the serum of patients with acquired bronchiectasis and healthy controls. This study was conducted on 77 subjects, divided into two lots: one lot comprising 57 patients with the aforementioned bronchiectasis and the second one comprising 20 healthy control subjects. The enzyme-linked immunosorbent assay method was used to perform the spectrophotometry test for the serum to detect and measure interleukin 1α and interleukin 10 levels. The results were significant from a statistical point on view but only in terms of the mean value of interleukin 10 that was much higher in the anti-inflammatory cytokine. Therefore, we can assume that there is a systemic anti-inflammatory reaction to the inflammation caused by bronchiectasis. Interleukin 1α is unspecific, and the values were similar in both groups; therefore, this interleukin should not be researched further in this direction. Future research is open in this field for the analysis of interleukin levels in bronchoalveolar lavage compared to serum levels.
Limited proteolysis and oxidative modification of proteins in the hepatocytes of patients with resistant forms of tuberculosis
Authors: Todoriko Lilia , Semianiv Ihor , Criṣan-Dabija Radu , Shevchenko Olʼha S. 
Published: December 2019

Abstract
The aim of this paper was to evaluate the oxidative modification of proteins and limited proteolysis in the hepatocytes of patients with resistant forms of pulmonary tuberculosis (TB).

Material and method:
This is a prospective pathomorphological study of 60 patients with confirmed pulmonary TB (clinically and anatomopathologically) deaths from various causes. To evaluate the intensity of free radical processes in hepatocytes, we used a methodology developed by Davydenko IS, 2003. Histological sections were stained with bromphenol blue by Michel-Calvo.

Results:
When comparing the digital data indicated in our study, it is evident that changes in proteins properties in average tendencies run virtually identically in the hepatocytes of different zones of the comparison group. Thus, the difference is unlikely (p > 0.05) when comparing red/blue ratio (specific staining of acid and basic proteins by Michel-Calvo) in the hepatocytes of zones I, II and III of the comparison group. A similar trend is observed in the analysis of average values of the optical density of a specific colouration on the free amino group of proteins by A. Yasuma and T. Ichikava.
The analysis of all parameters showed a linear increase in the intensity of oxidative protein modification and limited proteolysis from zone I to III (from the periportal to the centrolobular parts of the acinus) in all subgroups of the main group according to the acinus zone (by Rappoport).

Conclusions:
Pulmonary TB leads to increased processes of free radical oxidation of proteins with characteristic effects – increased proteolysis and oxidation of amino groups of proteins – in the hepatocytes of the liver.
EFFECT OF INTERCROPPING IN SHADING WITH CROTALARIA ON THE INITIAL DEVELOPMENT OF COFFEE TREE
Authors: Franco Junior Kleso Silva , Carvalho Terra Ana Beatriz , Florentino Ligiane Aparecida , Carvalho Julian Silva , Guimarães Bernardino Cangussu , Silva Nilton De Oliveira 
Published: December 2019

<p>Coffee cultivation in Brazil is still predominantly in full sun. However, the shading technique has gained prominence to increase the sustainability and profitability of production. Coffee intercropping legumes, besides contributing to shading, act as green manure, improving soil characteristics. Thus, in this study the objective was evaluating the shading intercropping effect on the initial development of coffee trees. The experiment was carried out at Sítio Santa Felicidade, municipality of Campestre - Southern Minas Gerais. Four species of the Crotalaria genus were used and one control treatment without any intermediate species, totaling 5 treatments. The planting was carried out in 4 replicates per treatment, in a randomized block system (DBC), with 16 coffee plants per plot. The 10 central plants were used for evaluation. The variables analyzed were: seedling setting (%), plant height (cm), leaf area index (LAI), number of plagiotropic branch internodes and 50 cm from ground level (cm²), temperature (°C) and soil moisture (%). Data were statistically interpreted by variance analysis and comparisons of averages performed by the Scott-Knott test at 5% probability, using the statistical software SISVAR®. It was observed that, except seedling setting (%) wherein there was no statistical difference among treatments, the other parameters showed positive responses in intercropping with crotalaria when compared to the control, showing the beneficial effect of the use of this legume when intercropped with coffee tree. </p>
Qualitative and Quantitative Analysis of Capsaicin from Capsicum annum Grown in Jordan
Authors: Ali Al-Samydai  , Talal Aburjai  , Walhan Alshaer  , Hanan Azzam  , Farah Al-Mamoori  
Published: December 2019

As there is an increasing demand for Capsaicin from pharmaceutical firms worldwide, the aim of the present study is to find a simple, fast, and reproducible method for its extraction from the fruit of capsicum annuum. Soxhlet extraction method using n-hexan as a solvent was used. Capsaicin was isolated and purified using a combination of column chromatography (CC), and thin-layer chromatography (TLC). High-Performance Liquid Chromatography (HPLC) was used for qualitative and quantitative analysis. Capsaicin was further identified by a spectroscopic method, including nuclear magnetic resonance (NMR) and Mass spectroscopy). The extraction yield was 11.5%, and Capsaicin concentrations in the extract was 8332.3 mg/kg with purity up to 73.95%, then purification of the extract was done by column chromatography, through using two solvent system until the purified Capsaicin detected and collected. Our results present a simple, fast, and reproducible method for the extraction of Capsaicin from the fruit of C. annuum with an almost high yield. The main advantage of the present method, in addition to its simplicity, it cut many steps that usually found in the literature.
PENAMAAN KULINER DALAM MASYARAKAT DAYAK MAANYAN
Authors: Septiana Dwiani 
Published: December 2019

The purpose of this research is to describe culinary naming in Dayak Maanyan community. This research uses the theory of onomastics as part of semantics science that learn names. The method used in this research is ethnographic research methods. According to Bramwell (2016) naming used in a society can be investigated by ethnographic research. The data for this research are collected by recording all lexicons related to culinary names and recording the understanding of Dayak Maanyan community about culinary in their society. The results indicate that in terms of word structure, culinary names in the Dayak Maanyan language have single forms, derivative forms, and compound forms. In terms of naming process, the culinary names in the Dayak Maanyan language can be grouped into seven types: naming based on similarity in shape, taste, cooking process, place of origin, borrowing from other languages, main ingredient, and arbitrary by the speakers.
ANALISIS STRUKTUR FUNGSIONAL MODEL A.J GREIMAS DALAM LEGENDA LANTING MIHING
Authors: Kambang NFN 
Published: December 2019

This study examines the Functional structure of Model A.J Greimas In Legends Lanting Mihing. The legend of Lanting Mihing is a folklore from the Kahayan river basin. This legend revolves around the courage of the central figure gained the expertise of how to make Lanting Mihing. The purpose of this writing is to know the structure in the legend story of Lanting Mihing the method in this writing is a qualitative method. To reveal the courage of this central figure then use functional structure theory proposed by A. J. Greimas. The results of Legend Lanting Mihing research led to a central figure named Bowak, there are 4 backgrounds in Legend Lanting Mihing ie background place, time, social, and psychology. Mandate delivered so that the younger generations do not forget the traditions that have been made by the ancestors, one of which way of making Lanting Mihing.