bluuebunny/crossref_metadata_2025_split huggingface dataset:
Independent predictors of secondary invasive pancreatic remnant tumors after initial resection of an intraductal papillary mucinous neoplasm: a nationwide large-scale survey in Japan
Authors: Takigawa Yutaka , Kitago Minoru , Matsui Junichi 
Published: July 2020

Abstract
Purpose
There is no standardized surveillance protocol after intraductal papillary mucinous neoplasm (IPMN) resection. We report the findings of a large-scale survey in Japan, investigating the independent predictors of secondary invasive tumors by analyzing the epidemiology of secondary tumors of the remnant pancreas after initial IPMN resection.

Methods
An institutional questionnaire about the remnant pancreas after pancreas resection was distributed at the 41st Annual Meeting of the Japanese Society of Pancreatic Surgery in Tokyo. We retrospectively analyzed the patient data including pathological diagnosis, postoperative outcomes, and evaluation methods.

Results
Redo pancreatectomy was performed for secondary disease in 213 (1.4%) of a total 15,777 patients. Eighty-eight of these 213 patients had undergone initial resection of IPMN. The types of secondary tumors after IPMN resection significantly depended on those of the primary tumors. Through short-interval and long-term follow-up, most of the secondary tumors were detected within 1–4 years. Logistic regression analysis revealed that the initial pathological diagnosis of invasive IPMN was an independent predictor of secondary invasive tumors in the remnant pancreas.

Conclusion
Primary invasive IPMN proved to be a significant predictor of secondary invasive IPMN. Both short-interval and long-term follow-up may help to determine the prognosis of patients after IPMN resection.
Role of endoscopic ultrasound for gallbladder disease
Authors: Tanaka Kazunari , Katanuma Akio , Hayashi Tsuyoshi , Kin Toshifumi , Takahashi Kuniyuki 
Published: July 2020

AbstractEndoscopic ultrasonography (EUS) has excellent spatial resolution and allows more detailed examination than abdominal ultrasonography (US) in terms of qualitative diagnosis of tumors and evaluation of tumor invasion depth. To understand the role of EUS in gallbladder disease, we need to understand the normal gallbladder wall structure and how to visualize it on EUS. In addition, gallbladder lesions can be classified into two broad categories: protuberant and wall-thickening lesions. Here, the features on EUS were outlined. We also outlined the current status of EUS-FNA for gallbladder lesions as there have been scattered reports of EUS-FNA in recent years.
Electrocorticography Evidence of Tactile Responses in Visual Cortices
Authors: Gaglianese Anna , Branco Mariana P. , Groen Iris I. A. , Benson Noah C. , Vansteensel Mariska J. , Murray Micah M. , Petridou Natalia , Ramsey Nick F. 
Published: July 2020

AbstractThere is ongoing debate regarding the extent to which human cortices are specialized for processing a given sensory input versus a given type of information, independently of the sensory source. Many neuroimaging and electrophysiological studies have reported that primary and extrastriate visual cortices respond to tactile and auditory stimulation, in addition to visual inputs, suggesting these cortices are intrinsically multisensory. In particular for tactile responses, few studies have proven neuronal processes in visual cortex in humans. Here, we assessed tactile responses in both low-level and extrastriate visual cortices using electrocorticography recordings in a human participant. Specifically, we observed significant spectral power increases in the high frequency band (30–100 Hz) in response to tactile stimuli, reportedly associated with spiking neuronal activity, in both low-level visual cortex (i.e. V2) and in the anterior part of the lateral occipital–temporal cortex. These sites were both involved in processing tactile information and responsive to visual stimulation. More generally, the present results add to a mounting literature in support of task-sensitive and sensory-independent mechanisms underlying functions like spatial, motion, and self-processing in the brain and extending from higher-level as well as to low-level cortices.
Triclosan changes community composition and selects for specific bacterial taxa in marine periphyton biofilms in low nanomolar concentrations
Authors: Martin Eriksson Karl , Kemal Sanli , Henrik Nilsson Rickard , Alexander Eiler , Natalia Corcoll , Henrik Johansson Carl , Thomas Backhaus , Hans Blanck , Erik Kristiansson 
Published: July 2020

AbstractThe antibacterial agent Triclosan (TCS) is a ubiquitous environmental contaminant due to its widespread use. Sensitivity to TCS varies substantially among eu- and pro-karyotic species and its risk for the marine environment remains to be better elucidated. In particular, the effects that TCS causes on marine microbial communities are largely unknown. In this study we therefore used 16S amplicon rDNA sequencing to investigate TCS effects on the bacterial composition in marine periphyton communities that developed under long-term exposure to different TCS concentrations. Exposure to TCS resulted in clear changes in bacterial composition already at concentrations of 1 to 3.16 nM. We conclude that TCS affects the structure of the bacterial part of periphyton communities at concentrations that actually occur in the marine environment. Sensitive taxa, whose abundance decreased significantly with increasing TCS concentrations, include the Rhodobiaceae and Rhodobacteraceae families of Alphaproteobacteria, and unidentified members of the Candidate division Parcubacteria. Tolerant taxa, whose abundance increased significantly with higher TCS concentrations, include the families Erythrobacteraceae (Alphaproteobacteria), Flavobacteriaceae (Bacteroidetes), Bdellovibrionaceae (Deltaproteobacteria), several families of Gammaproteobacteria, and members of the Candidate phylum Gracilibacteria. Our results demonstrate the variability of TCS sensitivity among bacteria, and that TCS can change marine bacterial composition at concentrations that have been detected in the marine environment.
COVID-19 Pandemic: An Insult Over Injury for Lebanon
Authors: Bizri Abdul Rahman , Khachfe Hussein H. , Fares Mohamad Y. , Musharrafieh Umayya 
Published: July 2020

AbstractThe outbreak of the novel coronavirus disease in 2019 (COVID-19) caused a plethora of challenges worldwide and tested healthcare systems across the six continents. Lebanon had recently faced harsh political and economic crises. We aim to describe the effect of COVID-19 on an already crisis-stricken country. A descriptive analysis of the burden of COVID-19 pandemic on Lebanon was performed. Relevant data on COVID-19 was retrieved from the Lebanese Ministry of Public Health from February 21 till June 13th, 2020. Results obtained were analyzed and a literature review was performed. 1422 confirmed COVID-19 cases were identified and reported in Lebanon by June 13th, 2020, comprising an incidence rate of 208/million persons. There has been a total of 31 deaths thus far, with a reported death rate of 5/million persons. The age group with the highest number of cases was 20–29 years. Beirut was the district with the highest number of cases (18%). The COVID-19 crisis has impacted the country on a multifactorial level. COVID-19 could not have come at a worse time for Lebanon. The country is on brink of bankruptcy, the healthcare system is struggling for survival and the government is striving to regain the trust of the population.
New results for an open time-dependent scheduling problem
Authors: Gawiejnowicz Stanisław , Kurc Wiesław 
Published: July 2020

AbstractWe present several new results for a single machine time-dependent scheduling problem of minimizing the total completion time of a set of linearly deteriorating jobs with unit basic processing times. First, we show new properties of cyclic transformations of V-shaped sequences for this problem. Next, applying the results, we prove a new necessary condition of schedule optimality for the considered problem, which decreases the previous bound on the cardinality of the set containing all possible optimal schedules by a multiplicative factor which is at most proportional to the reciprocal of the square root of the number of jobs. Finally, we compare the strength of the new and the previous necessary conditions by estimation of the numbers of schedules satisfying the respective conditions.
Thermal decomposition and spectral characterization of di[carbonatotetraamminecobalt(III)] sulfate trihydrate and the nature of its thermal decomposition products
Authors: Franguelli Fernanda Paiva , Barta-Holló Berta , Petruševski Vladimir M. , Sajó Istvan E. , Klébert Szilvia , Farkas Attila , Bódis Eszter , Szilágyi Imre Miklós , Pawar Rajendra P. , Kótai László 
Published: July 2020

AbstractDetailed vibrational (IR, Raman, far-IR) and thermal (TGA, TG–MS, DSC) analysis has been performed on di[κ1O,κ2O-carbonatotetraamminecobalt(III)] sulfate trihydrate, ([Co(NH3)4CO3]2SO4·3H2O (1). Its isothermic heating at 100 °C leads to formation of [Co(NH3)4CO3]2SO4(compound2). UV and IR studies showed that the distorted octahedral arrangement around cis-O2CoN4core in compound1does not change during dehydration, which explains the reversible water loss and ability of compound2to rehydrate into compound1. Compound2decomposes at ~ 240 °C in inert atmosphere giving final decomposition products, which are two modifications of nanosized metallic cobalt (hcp-15 nm, fcc-250 nm) and CoO (55 nm). The redox reaction results in N2as an ammonia oxidation product. The decomposition intermediate is a cobalt(II) compound, Co2O1,14+δ(SO4)0.86(δ = the oxygen surplus due to the presence of 2.8% of Co(III) ion). The same reaction in air atmosphere resulted in Co2O1.25+δ(SO4)0.75(δ = the oxygen surplus due to the presence of 5.3% of Co(III) ion (compound3a). Compound3ais oxidized in air at 793 °C into Co3O4. The compound3aexhibits catalytic activity in photodegradation in Congo red. The photodegradation process follows pseudo-first-order kinetic (kapp = 1.0 and 7.0. at pH = 3.4 and 5.25, respectively).
Flexible here-and-now decisions for two-stage multi-objective optimization: method and application to energy system design selection
Authors: Hollermann Dinah Elena , Goerigk Marc , Hoffrogge Dörthe Franzisca , Hennen Maike , Bardow André 
Published: July 2020

AbstractThe synthesis of energy systems is a two-stage optimization problem where design decisions have to be implemented here-and-now (first stage), while for the operation of installed components, we can wait-and-see (second stage). To identify a sustainable design, we need to account for both economical and environmental criteria leading to multi-objective optimization problems. However, multi-objective optimization does not lead to one optimal design but to multiple Pareto-efficient design options in general. Thus, the decision maker usually has to decide manually which design should finally be implemented. In this paper, we propose the flexible here-and-now decision (flex-hand) approach for automatic identification of one single design for multi-objective optimization. The approach minimizes the distance of the Pareto front based on one fixed design to the Pareto front allowing multiple designs. Uncertainty regarding parameters of future operations can be easily included through a robust extension of the flex-hand approach. Results of a real-world case study show that the obtained design is highly flexible to adapt operation to the considered objective functions. Thus, the design provides an energy system with the ability to adapt to a changing focus in decision criteria, e.g., due to changing political aims.
10th Anniversary of a Two-Stage Design in Bioequivalence. Why Has it Still Not Been Implemented?
Authors: Kaza Michał , Sokolovskyi Alexander , Rudzki Piotr J. 
Published: July 2020

Abstract
Purpose
In 2010 the European Medicines Agency allowed a two-stage design in bioequivalence studies. However, in the public domain there are mainly articles describing the theoretical and statistical base for the application of the two-stage design. One of the reasons seems to be the lack of practical guidance for the Sponsors on when and how the two-stage design can be beneficial in bioequivalence studies.

Methods
Different variants with positive and negative outcomes have been evaluated, including a pivotal study, pilot + pivotal study and two-stage study. The scientific perspective on the two-stage bioequivalence study has been confronted with the industrial one.

Results
Key information needed to conduct a bioequivalence study – such as in vitro data and pharmacokinetics – have been listed and organized into a decision scheme. Advantages and disadvantages of the two-stage design have been summarized.

Conclusion
The use of the two-stage design in bioequivalence studies seems to be a beneficial alternative to the 2 × 2 crossover study. Basic information on the properties of the active substance and the characteristics of the drug form are needed to make an initial decision to carry out the two-stage study.
CEO chairman controversy: evidence from the post financial crisis period
Authors: Gontarek Walter , Belghitar Yacine 
Published: July 2020

AbstractRegulators generally discourage bank CEOs also holding the role of board Chairman, as this governance structure can hinder independent decision-making and effective risk oversight. This study examines the issue of CEO Duality, identifying a positive relation to greater risk-taking across a battery of sensitivity tests. In further analysis, the study controls for differences in supervisory monitoring levels to examine its impact. Banks led by CEO Chairmen which are subject to lower levels of supervision continue to report a robust association to risk-taking, as before. However, this association dissipates for banks which are subject to heightened supervisory monitoring. These findings indicate that agency costs related to Duality may be moderated by greater regulation. This paper weighs-in on the controversy relating to a single contentious governance structure (i.e., CEO Duality), thus informing boards, regulators and researchers of the need to consider the overall interplay of monitoring mechanisms.
Quantifying the higher-order influence of scientific publications
Authors: Franceschet Massimo , Colavizza Giovanni 
Published: July 2020

AbstractCitation impact is commonly assessed using direct, first-order citation relations. We consider here instead the indirect influence of publications on new publications via citations. We present a novel method to quantify the higher-order citation influence of publications, considering both direct, or first-order, and indirect, or higher-order citations. In particular, we are interested in higher-order citation influence at the level of disciplines. We apply this method to the whole Web of Science data at the level of disciplines. We find that a significant amount of influence—42%—stems from higher-order citations. Furthermore, we show that higher-order citation influence is helpful to quantify and visualize citation flows among disciplines, and to assess their degree of interdisciplinarity.
Telling the story of solar energy meteorology into the satellite era by applying (co-citation) reference publication year spectroscopy
Authors: Scheidsteger Thomas , Haunschild Robin 
Published: July 2020

AbstractStudying the history of research fields by analyzing publication records and topical and/or keyword searches with reference publication year spectroscopy (RPYS) has been introduced as a powerful tool to identify the corresponding root publications. However, for some research fields (e.g., rather new and interdisciplinary fields) like solar energy meteorology, encompassing such research fields via a keyword- or topic-based search query is not feasible to get a reasonably exhaustive publication set. Therefore, we apply its variant RPYS-CO to all publications co-cited with two highly important marker papers, using the cited references explorer for inspecting the RPYS-CO results. We obtain two lists of seminal papers, which are able to adequately tell us the story of solar energy meteorology up to the 1990s, respectively in its subfield using satellite-based methods for solar irradiance estimation even to very recent years. Consequently, we recommend this method to gain valuable insights in (new) research fields.
Education for Loneliness as a Consequence of Moral Decision-Making: An Issue of Moral Virtues
Authors: Horowski Jarosław 
Published: July 2020

AbstractThe direct reference point for these analyses is the process of making moral decisions, but a particular point of interest is the difficulty associated with making decisions when acting subjects are aware that their choice of moral good can lead to the breakdown of relationships with those close to them (family members or friends) or to their exclusion from the group(s) that have been most important to them so far in their lives, consequently causing them to experience loneliness. This difficulty is a challenge for education, which in supporting the moral development of a maturing person should prepare her/him for choosing moral good even if this requires personal sacrifices. In these analyses, assuming that knowledge of moral good is not sufficient for morally good actions, I refer mainly to the virtues of character that facilitate making morally good decisions and I seek the answer to the question: what character traits (moral virtues) should be shaped in maturing persons, so that as adults they can resist moral evil, even when this will clearly lead to the experience of loneliness? I propose these character traits as expressing moral virtues—especially the cardinal virtues of prudence, justice, temperance and fortitude (neo-Thomistic approach). In this way, I join in the discussion relating to the teleology of education. I do not touch on the methodology of education, however. The argument is presented in two parts. In the first, I introduce the problem of decision-making implying consent to loneliness. In the second, I reflect on the characteristics of a person who is capable of making such a decision.
Continuous Dynamics Related to Monotone Inclusions and Non-Smooth Optimization Problems
Authors: Csetnek Ernö Robert 
Published: July 2020

AbstractThe aim of this survey is to present the main important techniques and tools from variational analysis used for first and second order dynamical systems of implicit type for solving monotone inclusions and non-smooth optimization problems. The differential equations are expressed by means of the resolvent (in case of a maximally monotone set valued operator) or the proximal operator for non-smooth functions. The asymptotic analysis of the trajectories generated relies on Lyapunov theory, where the appropriate energy functional plays a decisive role. While the most part of the paper is related to monotone inclusions and convex optimization problems in the variational case, we present also results for dynamical systems for solving non-convex optimization problems, where the Kurdyka-Łojasiewicz property is used.
Gender differences in the susceptibility of hospital-acquired acute kidney injury: more questions than answers
Authors: Schiffl Helmut 
Published: July 2020

AbstractHospital-acquired acute kidney injury (HA-AKI) is a heterogeneous renal syndrome which occurs in different clinical settings. It is characterized by multiple aetiologies, various pathogeneses and unpredictable outcomes. HA-AKI, once predominantly viewed as a self-limited and reversible short-term condition, is now recognized as a harbinger for chronic kidney disease and a cause of long-term morbidity with an increased risk of cardiovascular, renal and cancer mortality. Recent clinical studies contradict the generally held belief that female sex is a risk factor for HA-AKI. They show, consistent with basic research performed with experimental models of AKI, that only male sex is associated with HA-AKI. The presence of testosterone, more likely than the absence of estrogen, plays a critical role in sex differences in the susceptibility of ischemia/reperfusion kidney injury. The conflicting data in epidemiological studies related to sex as susceptibility variable for human AKI, underscore the need for more rigorous, well designed observational studies taking into account the menopausal status and hormone therapy.
The role of individual personality in conceptualizing and measuring group characteristics
Authors: Deckers Marius , Altmann Tobias , Roth Marcus 
Published: July 2020

AbstractIn previous research, group characteristics have often been measured without taking the individual perspective of the group members into account. Therefore, the influence of individual personality (and other individual-level characteristics) on group characteristic ratings beyond the influence of the actual group remains largely unexplored. Additionally, some studies use group means of individual personality as group characteristics, however, evidence for interrelations or differences between these approaches has not yet been empirically based. In the present study, we employed a sample of 301 individuals from 54 teams, all of which rated both characteristics of themselves and their teams. By averaging both self-ratings and group-ratings within each team, we were able to compare both approaches to group characteristics and found them to likely measure unrelated constructs. We also found influences of individual Extraversion and Agreeableness from the HEXACO model on direct group characteristic ratings beyond the influence of the actual group. Years of work experience and work strain operationalized through burnout symptoms did not predict group characteristic ratings beyond the influence of the actual group and individual personality. Our findings imply that individual ratings of a group characteristic are influenced to a larger degree by the raters’ individual perspectives than by the presumed actual group characteristic itself. Further implications for research applying individual personality to groups are discussed.
Feeding the food insecure in Britain: learning from the 2020 COVID-19 crisis
Authors: Barker Margo , Russell Jean 
Published: July 2020

AbstractThe lockdown in Britain has rendered a large proportion of the population economically vulnerable and has at least quadrupled demand for emergency food relief. This paper looks critically at response to the crisis from the government and the voluntary sector with respect to provision of emergency food. In doing so, it has exposed gaps in understanding of the vagaries of the food supply for certain population groups and systemic weaknesses in the current system of emergency food aid. We make recommendations for healthier governmental capacity to react to a food security crisis, better relationships between the government and the voluntary sector, and further research into the dietary constraints of the precariate. Importantly, the social system needs to be responsive to short-term changes in people’s income if people are not to fall into food insecurity.