bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Profile and Outcome of Indian Children with Aromatic L-Amino Acid Decarboxylase Deficiency: A primary CSF Neurotransmitter Disorder Mimicking as Dyskinetic Cerebral Palsy
Authors: Gowda Vykuntaraju K. , Vegda Hemadri , Nagarajan Balamurugan B. , Shivappa Sanjay K. 
Published: July 2020

AbstractAromatic L-amino acid decarboxylase (AADC) deficiency is a disorder of neurotransmitter synthesis. It presents with psychomotor delay, dystonia, oculogyric crisis, and autonomic features. There is paucity of literature on this disorder. Hence, we are reporting this series with an objective to study profile and outcome of Indian children with AADC deficiency. In this retrospective review, all case records of genetically confirmed cases of AADC deficiency at the pediatric neurology department in a tertiary care hospital, from March 2014 to March 2020, were analyzed. The data were extracted in a predesigned proforma and analyzed. Out of seven cases, five were males. Median age of onset of symptoms was 4 months but median age of diagnosis was 12 months. All of them had developmental delay, oculogyric crisis, dystonia, increased sweating, intermittent fever, feeding and sleep disturbance, irritability, failure to thrive, axial hypotonia with dyskinetic quadriparesis, and normal magnetic resonance imaging (MRI) of brain and electroencephalogram (EEG). All of them were treated with pyridoxal 5-phosphate, trihexyphenidyl and pramipexole and six cases, in addition, were given bromocriptine. One case was additionally treated with selegiline. One case showed good improvement, five showed partial improvement, and one case expired. In conclusion, AADC deficiency should be suspected in any child with dyskinetic quadriparesis, oculogyric crisis, autonomic disturbances like increased sweating, intermittent fever, and sleep disturbance with normal neuroimaging.
Profile of Indian Children with Childhood Ataxia and Central Nervous System Hypomyelination/Vanishing White Matter Disease: A Single Center Experience from Southern India
Authors: Gowda Vykuntaraju K. , Srinivasan Varunvenkat M. , Nagarajan Balamurugan , Bhat Maya , Shivappa Sanjay K. , Benakappa Naveen 
Published: July 2020

Abstract
Background Childhood ataxia with central nervous system hypomyelination (CACH) is a recently described childhood inherited white matter disease, caused by mutations in any of the five genes encoding eukaryotic translation initiation factor (eIF2B).
Methods Retrospective review of the charts of children with CACH was performed from January 2014 to March 2020 at tertiary care center from Southern India. Diagnosis was based on magnetic resonance imaging (MRI) criteria or genetic testing.
Results Total number of children with CACH enrolled were 18. Male/female ratio was 10:8. Mean age of presentation was 37.11 months (range =  6–144 months). Affected siblings were seen in five (28%) cases. All children had spasticity, ataxia, and diffuse white matter changes with similar signal as cerebrospinal fluid on all pulse sequences on MRI brain. Of the 18 children, only nine are alive. Duration of illness among deceased children was 9.6667 months (range = 2–16 months). Waxing and waning of symptoms were seen in seven cases. Genetic analysis of EIF2B gene was performed in five cases, among which three mutations were novel.
Conclusion A diagnosis of childhood ataxia with central nervous system hypomyelination should be considered in patients presenting with acute onset neuroregression following infection or trauma with associated neuroimaging showing classical white matter findings.
Caused-Motion and Caused-Position
Authors: Joo Ian , Liu Meichun 
Published: July 2020

AbstractAccording toGoldberg (1995), placement verbs (such asput) are instantiated in the Caused-Motion Construction.Rohde (2001), however, argued that placement verbs in fact occur in a different construction, which she names the Caused-Position Construction, whose semantic value is not ‘cause to move’ but rather ‘cause to be positioned’. The present paper redefines and justifies the postulation of Caused-Position Construction. The Caused-Position Construction is compatible with not only placement verbs but also a variety of other verbs, such as verbs of creation (writeorbuild) or certain stative verbs (wantorneed), many of which also occur in the Locative Inversion construction. Further, a similar distinction between Caused-Motion and Caused-Position can be attested in Mandarin as well, which suggests that the distinction between two patterns of spatial causation may not be idiosyncratically confined to the English language but motivated by the general patterns of human cognition.
‘More than a million’: the politics of accounting for the dead of the Rwandan genocide
Authors: Reydams Luc 
Published: July 2020

ABSTRACT
Accounting for the dead after a humanitarian catastrophe is often fraught with methodological and/or political pitfalls. The genocide against the Tutsi in Rwanda is a case in point. A UN Commission of Experts estimated that between April and July 1994 at least 500,000 civilians had been murdered. The post-genocide Rwandan government soon made clear that foreign help with demographic and forensic investigations was neither appreciated nor needed, and proceeded with its own counts of genocide victims. The article critically examines these counts; contrasts them with accounting efforts after the Bosnian conflict of the mid 1990s; compares the official Rwandan numbers with scholarly estimates; proposes an alternative method for calculating the death toll; and concludes that the official death toll roughly doubled the number of genocide victims. The article provides insight into how history is written in the new Rwanda.
Finite element simulation for sensitivity measurement of a shear horizontal surface acoustic wave micro pressure sensor with a groove structure
Authors: Li Yuanyuan , Yang Jian , Jiang Bei , Cao Le , Shen Xiangyi , Shao Meng 
Published: July 2020

Abstract
Shear horizontal surface acoustic wave (SH-SAW) sensors have great application potential due to their advantages of easy integration, miniaturization and suitability in liquid environments. In this paper, the finite element method is used to analyse a new SH-SAW micro pressure sensor, in which there are many groove structures along the direction of wave propagation on the delay path. We use the transient response simulation method to calculate and analyse the output voltage signal at the output interdigital transducer and surface average stress at the delay path of this new SH-SAW sensor, and its pressure sensitivity is analysed by uniformly applying an appropriate surface pressure on the resonant beam formed after grooving. The simulation results show that the surface average stress can be enhanced in a certain range of groove depth during the vibration of the groove structure. When the groove depth and width are set to 0.7 μm and 0.5 μm, respectively, the sensitivity of the SH-SAW sensor with a groove structure is four times higher than that of the traditional SH-SAW sensor. The increase of pressure sensitivity is the result of the increase of average stress caused by the groove structure. The new groove structure SH-SAW sensor provides a new basis for research on high-sensitivity micro-pressure sensors and lays a foundation for subsequent device design and manufacture.
Influence of ion-induced secondary electron emission parameters in PICMC plasma simulations with experimental validation in DC cylindrical diode and magnetron discharges
Authors: Richard T , Furno I , Sublet A , Taborelli M 
Published: July 2020

Abstract
Niobium thin films are used at CERN (European Organization for Nuclear Research) for coatings of superconducting radio-frequency (SRF) accelerating cavities. Numerical simulations can help to better understand the physical processes involved in such coatings and provide predictions of thin film properties. In this article, particle-in-cell Monte Carlo 3D plasma simulations are validated against experimental data in a coaxial cylindrical system allowing both DC diode and DC magnetron operation. A proper choice of ion induced secondary electron emission parameters enables to match experimental and simulated discharge currents and voltages, with argon as the process gas and niobium as the target element. Langmuir probe measurements are presented to further support simulation results. The choice of argon gas with a niobium target is driven by CERN applications, but the methodology described in this paper is applicable to other discharge gases and target elements.Validation of plasma simulations is the first step towards developing an accurate methodology for predicting thin film coatings characteristics in complex objects such as SRF cavities.
Controlled plasma–droplet interactions: a quantitative study of OH transfer in plasma–liquid interaction
Authors: Oinuma Gaku , Nayak Gaurav , Du Yanjun , Bruggeman Peter J 
Published: July 2020

Abstract
Plasmas in contact with liquids are a rich source of OH radicals and have been extensively studied in the last decade to leverage the ability to generate chemically reactive species in gas phase plasmas to decompose organics. Multiphase transfer of OH radicals is highly transport limited and to overcome transport limits, the plasma activation of aerosols, small liquid droplets, interspersed in the plasma has been proposed. In this work, we report a combined experimental and modeling study of a controlled plasma–droplet interaction experiment using a diffuse RF glow discharge in He + 0.2% H2O with detailed plasma diagnostics, ex situ analysis of the plasma-induced chemistry in the droplet containing formate, droplet trajectory and size measurements. This enables a quantitative study of the reactivity transfer of OH from the gas phase plasma to the liquid phase and how its diffusion limitations impact formate decomposition in the water droplet. For a droplet with a diameter of 36 μm, we observed 50% reduction in formate concentration in the droplets after plasma treatment for droplet residence times in the plasma of ∼10 ms. These short droplet residence times in the plasma allow in some cases for droplet size reductions of ∼5% in spite gas temperatures of 360 K. A one-dimensional reaction–diffusion model was used to calculate the OH transport and formate oxidation inside the droplet and was able to predict the conversion of formate by plasma in a droplet without any fitting parameters. The model further shows that formate conversion is dominated by near-interfacial reactions with OH radicals and is limited by diffusion of formate in the droplet. The results show that a controlled plasma–micro-droplet reactor as reported in this study might be an excellent tool for detailed quantitative plasma–liquid interaction studies.
The photon vortex beam in rotating medium
Authors: Wei Jianye , Jia Wei , Peng Xubiao , Zhao Qing , Ge Molin 
Published: July 2020

Abstract
In this paper, we demonstrate that there are vortex beam solutions for the photon in the rotating medium. By constructing the photon wave function with Riemann–Silberstein vector, we derive the dynamic equation of the photon in moving medium from the Maxwell equations and the non-relativistic Minkowski relations. In case of the stationary state, the dynamic equation of the photon can be written as a Dirac-like equation, where the velocity of the medium plays the role of a vector potential. By giving the medium different forms of rotating velocity fields, we obtain different vortex beam solutions of the photon, such as the diffracting and non-diffracting Laguerre–Gaussian (LG) beam solutions via proper approximations. For the diffracting LG beam solution, we acquire a new term arising from the medium rotation that can change the Gouy phase, and then accordingly predict the rotation behavior of the photon interference pattern. In addition, the rotation of the medium can lead to the change of the relative intensity distribution of the interference pattern. Furthermore, our theory predicts the existence of the Landau levels of transverse photon energy in the nondiffracting LG beam solution.
Low-dimensional vanadium dioxide nanomaterials: fabrication, properties and applications
Authors: Liu Chang , Wang Yang , Tian Ziao , Mei Yongfeng 
Published: July 2020

Abstract
Vanadium dioxide (VO2) receives a great deal of attention because of its intriguing properties of metal-insulator transition and its wide applications in electronics, optoelecronics, smart coatings, and so on. To further enhance the performance of their applications, low dimensional VO2 nanomaterials, such as nanobeams and nanomembranes, have become a research hotspot due to their structural advantages, including large specific surface area, convenient miniaturization, light weight, and softness. In this paper, the recent studies of low dimensional VO2 nanomaterials are discussed, focusing on their preparation methods, properties, and applications, as well as the existing challenges and future prospectives.
The imaginary part of the high-harmonic cutoff
Authors: Pisanty Emilio , Ciappina Marcelo F , Lewenstein Maciej 
Published: July 2020

Abstract
High-harmonic generation—the emission of high-frequency radiation by the ionization and subsequent recombination of an atomic electron driven by a strong laser field—is widely understood using a quasiclassical trajectory formalism, derived from a saddle-point approximation, where each saddle corresponds to a complex-valued trajectory whose recombination contributes to the harmonic emission. However, the classification of these saddle points into individual quantum orbits remains a high-friction part of the formalism. Here we present a scheme to classify these trajectories, based on a natural identification of the (complex) time that corresponds to the harmonic cutoff. This identification also provides a natural complex value for the cutoff energy, whose imaginary part controls the strength of quantum-path interference between the quantum orbits that meet at the cutoff. Our construction gives an efficient method to evaluate the location and brightness of the cutoff for a wide class of driver waveforms by solving a single saddle-point equation. It also allows us to explore the intricate topologies of the Riemann surfaces formed by the quantum orbits induced by nontrivial waveforms.
Notions of Stein spaces in non-Archimedean geometry
Authors: Maculan Marco , Poineau Jérôme 
Published: July 2020

Let

k
k

be a non-Archimedean complete valued field and let

X
X

be a

k
k

-analytic space in the sense of Berkovich. In this note, we prove the equivalence between three properties: (1) for every complete valued extension

k
′

k’

of

k
k

, every coherent sheaf on

X

×

k

k
′

X \times _{k} k’

is acyclic; (2)

X
X

is Stein in the sense of complex geometry (holomorphically separated, holomorphically convex), and higher cohomology groups of the structure sheaf vanish (this latter hypothesis is crucial if, for instance,

X
X

is compact); (3)

X
X

admits a suitable exhaustion by compact analytic domains considered by Liu in his counter-example to the cohomological criterion for affinoidicity.

When

X
X

has no boundary the characterization is simpler: in (2) the vanishing of higher cohomology groups of the structure sheaf is no longer needed, so that we recover the usual notion of Stein space in complex geometry; in (3) the domains considered by Liu can be replaced by affinoid domains, which leads us back to Kiehl’s definition of Stein space.
Evidence for pollination ecotypes in the African cycadEncephalartos ghellinckii(Zamiaceae)
Authors: Suinyuy Terence N , Johnson Steven D 
Published: July 2020

AbstractGeographical variation in pollinator assemblages can result in divergent selective pressures and consequently drive the evolution of phenotypically distinct pollination ecotypes. Intraspecific divergence in pollination systems is well known among angiosperms, but is poorly studied among gymnosperms, often considered a relictual group not undergoing recent radiations. We investigated whether geographical divergence in the chemistry of volatiles emitted by cones of the cycad Encephalartos ghellinckii can be linked with functions for attracting different pollinators. We tested the pollination effectiveness of different insects in terms of deposition of fluorescent dye on micropyles and investigated whether daily fluctuations in cone temperature are correlated with insect pollinator activity. We also performed field bioassays to test the responses of insects to key volatiles and laboratory y-maze experiments to determine whether insects discriminate among cones of the two forms. Experiments confirmed that the beetles Metacucujus goodei and Erotylidae sp. nov. are the most effective pollinators of the mountain and lowland forms, respectively. A peak in cone temperatures in the afternoon was associated with extensive movement of insects among cones of mountain plants, but only limited movement of insects among cones of lowland plants. In field bioassays, Metacucujus goodei beetles were attracted mainly to (3E)-1,3-octadiene, a dominant component of the scent of mountain plants, whereas Erotylidae sp. nov. responded to camphene, a dominant component of the scent of lowland plants. When offered a choice, beetles preferred cones from the local population over those from a different population. The results suggest that E. ghellinckii consists of two pollination ecotypes with modifications in scent chemistry being correlated with an apparent shift between different pollinators. The relationship between thermogenesis and pollinator activities varies between ecotypes, with mountain plants showing a push–pull type of system and the lowland plants a system in which insects depart from cones with declining quality. This study highlights the role of insect pollinators in driving the evolution of cycads and the importance of thermogenesis and volatile emissions for mediating some beetle pollination systems.
Performance of three iGrav superconducting gravity meters before and after transport to remote monitoring sites
Authors: Schäfer Florian , Jousset Philippe , Güntner Andreas , Erbas Kemal , Hinderer Jacques , Rosat Séverine , Voigt Christian , Schöne Tilo , Warburton Richard 
Published: July 2020

SUMMARY
High spatial and temporal resolution of gravity observations allows quantifying and understanding mass changes in volcanoes, geothermal or other complex geosystems. For this purpose, accurate gravity meters are required. However, transport of the gravity meters to remote study areas may affect the instrument's performance. In this work, we analyse the continuous measurements of three iGrav superconducting gravity meters (iGrav006, iGrav015 and iGrav032), before and after transport between different monitoring sites. For 4 months, we performed comparison measurements in a gravimetric observatory (J9, Strasbourg) where the three iGravs were subjected to the same environmental conditions. Subsequently, we transported them to Þeistareykir, a remote geothermal field in North Iceland. We examine the stability of three instrumental parameters: the calibration factors, noise levels and drift behaviour. For determining the calibration factor of each instrument, we used three methods: First, we performed relative calibration using side-by-side measurements with an observatory gravity meter (iOSG023) at J9. Secondly, we performed absolute calibration by comparing iGrav data and absolute gravity measurements (FG5#206) at J9 and Þeistareykir. Thirdly, we also developed an alternative method, based on intercomparison between pairs of iGravs to check the stability of relative calibration before and after transport to Iceland. The results show that observed changes of the relative calibration factors by transport were less than or equal to 0.01 per cent. Instrumental noise levels were similar before and after transport, whereas periods of high environmental noise at the Icelandic site limited the stability of the absolute calibration measurements, with uncertainties above 0.64 per cent (6 nm s–2 V–1). The initial transient drift of the iGravs was monotonically decreasing and seemed to be unaffected by transport when the 4K operating temperatures were maintained. However, it turned out that this cold transport (at 4 K) or sensor preparation procedures before transport may cause a change in the long-term quasi-linear drift rates (e.g. iGrav015 and iGrav032) and they had to be determined again after transport by absolute gravity measurements.
Invasive Mucinous Neoplasm of the Appendix Masquerading as Recurrent Urinary Tract Infections: a Case Report
Authors: Ciampa Maeghan L , Chohonis James P , Otto Richard S , Franklin Benjamin T 
Published: July 2020

Abstract
We report on a case of a healthy male patient who was referred to Urology for recurrent persistent urinary tract infections. Investigation revealed a large intraabdominal inflammatory collection abutting the cecum and bladder suspicious for ruptured appendicitis and colovesical fistula. He was taken to the operating room for exploratory laparotomy with General Surgery and Urology and found to have a ruptured appendix secondary to mucinous appendiceal neoplasm with invasion into the cecum and the bladder wall. He then underwent systemic chemotherapy followed by hyperthermic intraperitoneal chemotherapy. He is well with stable right lower quadrant inflammatory collection and without evidence of metastatic disease 22 months following initial surgery. This case presents a rare presentation of a rare disease process that is easy to misdiagnose or be delayed in diagnosis because of its vague and often varied presentation.
Challenges for China's medical education in the coming post-COVID-19 era
Authors: Shao Li , Zhao Weijie 
Published: July 2020

Abstract
The year of 2020 has been overshadowed by the COVID-19 pandemic. Medical workers throughout China have played critical roles in battling severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) and saving lives. The whole of society has now fully realized the significance of medical workers and many began to think about medical education in China: How can we further improve medical education for the next generation of clinicians, medical scientists, nurses, public-health workers and administrators related to medical care, so that they are well prepared to meet societal needs for medical care in the ever-changing world? In this panel discussion, medical-education experts from several prominent medical schools in China gathered to discuss the reform and future development of China's medical education.
Xiang Chen

President of Xiangya School of Medicine, Vice President of Central South University, Changsha, China
Baorong Chi

Professor of Norman Bethune Health Science Center of Jilin University, Changchun, China
Yiqun Hu

Vice Chancellor of Shanghai Jiao Tong University School of Medicine, Shanghai, China
Yang Ke

Professor of Peking University Health Science Center, former Vice President of Peking University, Beijing, China
Ming Kuang

Vice President of Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
Mengfeng Li

President of Southern Medical University, Guangzhou, China
Hongbing Shen

President of Nanjing Medical University, Nanjing, China
Xuehong Wan

Professor of West China Medical Center, Vice President of Graduate School of Sichuan University, Chengdu, China
Hong Yan

President of Xi’an Jiaotong University Health Science Center, Vice President of Xi’an Jiaotong University, Xi’an, China
Guoqiang Chen (Chair)

Chancellor of Shanghai Jiao Tong University School of Medicine, Vice President of Shanghai Jiao Tong University, Shanghai, China