bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of firm-level attributes on listed real estate company performance
Authors: Haran Martin Edward , Lo Daniel , McCord Michael , Davis Peadar , Lim Lay Cheng 
Published: August 2020

PurposeThe purpose of this paper is to test the extent to which company-specific attributes including market capitalisation, capital structure and investment focus impact upon the performance of European listed real estate companies. Enhanced understanding of firm-level performance drivers is important for investors in order to diversify their investment portfolios and to mitigate company-specific risks at different points in the real estate cycle.Design/methodology/approachThe study centres on six key listed European real estate markets selected on the basis of market capitalisation, diversity, transparency and maturity. A series of statistical tests are undertaken using EPRA and Bloomberg data for the period of 2007–2017 using 113 listed property companies, all of whom were contemporaneous constituents of EPRA indices in this period. A series of customised performance indices were constructed to evaluate firm-level performance attributes.FindingsFirm-level attributes collectively account for more variation of risk-adjusted return than sector-level attributes over the investigation period. The impact of firm-specific attributes on performance varies significantly from country to country attributable to the contrasting cyclical property market trends in the pre– and post–Global Financial Crisis period. REITs outperformed non-REITs on a risk-adjusted basis attributed to the strong performance of “niche” market entrants allied with stronger regulatory structure. Finally, the findings showcase that sector specialist firms outperform diversified companies inferring that investors should seek to attain diversification through portfolio-based approaches rather than firm-level strategies.Practical implicationsThe results have implications for real estate companies aiming to raise capital internally for growth as higher return on equity in general signals reduced cost of capital. Secondly, the findings should be of practical use to multinationals specialising in international real estate trading in designing their business plans in general and formulating cross-country investment strategies in particular. Last but not least, a more refined conceptualisation of corporate-level performance drivers should complement existing professional practices in relation to business/company appraisal.Originality/valueThe research integrates EPRA and Bloomberg data sets to create a series of bespoke index constructs to measure the impact of firm-specific attributes on European listed real estate companies. Additionally, the authors construct a Herfindahl Index (H.I.) to further the debate on the impacts of diversification within the listed real estate sector. This serves to further heighten investor understanding of investment allocation and portfolio optimisation strategies for the listed real estate sector given the increasingly diverse range of investment opportunities within emerging sub-markets.
Perinatal mental health amongst refugee and asylum-seeking women in the UK
Authors: Giscombe Tkaya , Hui Ada , Stickley Theodore 
Published: August 2020

Purpose
Refugee and asylum-seeking women are particularly vulnerable to experiencing mental health difficulties during the perinatal period, with social factors compounding these experiences. Research is limited into the mental health needs of perinatal women who are refugees or seeking asylum. The purpose of this paper is to examine the best available international evidence on this topic and to discuss the findings with relevance to the UK context.

Design/methodology/approach
A modified population, intervention, comparison, outcome was used to formulate the research question and search strategy. Databases searched were: cumulative index of nursing and allied health literature, Medline, PsychINFO, Web of Science and Scopus. Guided by the Preferred Reporting Items for Systematic Reviews and Meta-analysis framework, results were screened against an inclusion and exclusion criteria. Each study underwent a quality assessment in which they were appraised using the mixed methods appraisal tool.

Findings
Eight papers were retrieved, and a thematic analysis was conducted. Two major themes were identified: mental health needs and social influences. Refugees and asylum seekers are likely to have experienced trauma as reasons for migration. Post-migration stressors, including hostility and dispersal from social networks, lead to cumulative trauma. These each add to the mental health needs of perinatal refugee and asylum-seeking women that cannot be ignored by policymakers, health and social care services or professionals.

Originality/value
Refugee and asylum-seeking women are particularly vulnerable to mental health difficulties in the perinatal period. Stressors accumulated pre-, during and post-migration to the host country exacerbate mental distress. In the UK, the treatment of this population may be detrimental to their mental health, prompting the need for greater critical awareness of the socioecological environment that refugee or asylum-seeking women experience.
Optimal currency hedge and the carry trade
Authors: Filipozzi Fabio , Harkmann Kersti 
Published: August 2020

PurposeThis paper aims to investigate the efficiency of different hedging strategies for an investor holding a portfolio of foreign currency bonds.Design/methodology/approachThe simplest strategies of no hedge and fully hedged are compared with the more sophisticated strategies of the ordinary least squares (OLS) approach and the optimal hedge ratios found by the dynamic conditional correlation-generalised autoregressive conditional heteroskedasticity approach.FindingsThe sophisticated hedging strategies are found to be superior to the simple strategies because they lower the portfolio risk in domestic currency terms and improve the Sharpe ratios for multi-asset portfolios. The analyses also show that both the OLS and dynamic hedging strategies imply holding a limited carry position by being long in high-yielding currencies but short in low-yielding currencies.Originality/valueThe performance of multi-currency portfolios is examined using more realistic assumptions than in the previous literature, including a weekly frequency and a constraint of no short selling. Furthermore, carry trades are shown to be part of an optimal portfolio.
The impact of personality, morphotype and shore height on temperature‐mediated behavioural responses in the beadlet anemone Actinia equina
Authors: Maskrey Daniel K. , Sneddon Lynne U. , Arnold Kathryn E. , Wolfenden David C. C. , Thomson Jack S. 
Published: August 2020

Abstract

Between‐individual variation in behavioural phenotype, termed personality, is an important determinant of how populations cope with acute environmental fluctuation related to climate change.

Personality in the beadlet sea anemone Actinia equina is linked to genetically distinct morphotypes, which are associated with different heights on the shore. In the intertidal zone, high‐shore environments experience more environmental fluctuation due to longer periods of exposure, and animals adapted to live in these environments are predicted to deal more effectively with environmental perturbation than their low‐shore counterparts.

We collected beadlet anemones of two different morphotypes from three different shore heights. We investigated variation in two behaviours at three different temperatures and in a temporal control treatment where the temperature was not changed: startle response time, the time it took an anemone to re‐extend its tentacles after a threatening stimulus, and immersion response time, the time to re‐extend tentacles after simulated tidal immersion. These behaviours reflect risk‐taking and allow individuals to be categorized as bold, shy or intermediate based upon response times.

Both behaviours showed significant changes as the temperature increased. For immersion response, the morphotype associated with the low‐shore‐lengthened response times at high temperatures. For startle response, all animals lengthened their response times at high temperatures but animals collected from the low‐shore lengthened theirs to the greatest degree. At the individual level, although control individuals exhibited temporal changes in their response times, a clear effect of temperature was present in both behaviours. Shy and bold individuals became more intermediate at higher temperatures in immersion response (this effect was present to a lesser degree in control individuals), while intermediate individuals raised their response times at higher temperatures for startle response.

Given that prolonged tentacle retraction reduces foraging opportunities and can negatively impact respiratory efficiency, our data suggest that some individuals within a single population of A. equina, particularly those associated with the lower shore, may exhibit less effective behavioural responses to temperature shifts than others. These findings demonstrate that acute temperature changes influence risk‐taking, and could have profound short and long‐term implications for survival in the face of climate change.
Occupational therapy, cancer, and occupation‐centred practice: impact of training in the model of human occupation
Authors: Bowyer Patricia , Muñoz Lauro , Tiongco Cynthia Gorter , Tkach Melanie Morriss , Moore Cary C. , Burton Brittney , Lim Daisy 
Published: August 2020

AbstractIntroductionThis study examined the influence of training in an occupation‐centred model on the practice of occupational therapists working in a cancer hospital. There is an increased need for occupation‐based rehabilitation services for individuals with and surviving cancer. Incorporating an occupation‐centred model into practice has unique challenges for occupational therapists working in oncology settings. Utilizing an occupation‐centred model of practice may influence the therapeutic reasoning of occupational therapists.MethodsA generic qualitative inquiry (Patton, 2015) was used to examine therapeutic reasoning as related to post‐professional training in a specific occupation‐centred model, the Model of Human Occupation (MOHO). Initially, ten occupational therapists with various levels of experience, working across populations in a large cancer centre completed a training session about the MOHO. This was followed by participation in monthly focus groups with an emphasis on the use of MOHO in daily practice (Taylor, 2017). Focus group sessions were video recorded and transcribed. The transcripts were then analysed using open coding and theme generation (Patton, 2015).ResultsThree major themes were extracted from the data during the thematic analysis: understanding and using MOHO language; challenges in incorporating a conceptual model of occupation‐centred practice in an oncology setting; and therapeutic reasoning implications. Patterns in the themes indicated a progression from learning the model, to applying the model, to reflection on practice.ConclusionPost‐professional training in an occupation‐based model influenced the therapeutic reasoning and practice of occupational therapists in an oncology setting.
Control of pathogenic and spoilage bacteria in meat and meat products by high pressure: Challenges and future perspectives
Authors: Li Hui , Sun Xiaohong , Liao Xiaojun , Gänzle Michael 
Published: August 2020

AbstractHigh‐pressure processing is among the most widely used nonthermal intervention to reduce pathogenic and spoilage bacteria in meat and meat products. However, resistance of pathogenic bacteria strains in meats at the current maximum commercial equipment of 600 MPa questions the ability of inactivation by its application in meats. Pathogens including Escherichia coli, Listeria, and Salmonelle, and spoilage microbiota including lactic acid bacteria dominate in raw meat, ready‐to‐eat, and packaged meat products. Improved understanding on the mechanisms of the pressure resistance is needed for optimizing the conditions of pressure treatment to effectively decontaminate harmful bacteria. Effective control of the pressure‐resistant pathogens and spoilage organisms in meats can be realized by the combination of high pressure with application of mild temperature and/or other hurdles including antimicrobial agents and/or competitive microbiota. This review summarized applications, mechanisms, and challenges of high pressure on meats from the perspective of microbiology, which are important for improving the understanding and optimizing the conditions of pressure treatment in the future.
Where have our patients gone? The impact of COVID‐19 on stroke imaging and intervention at an Australian stroke center
Authors: Amukotuwa Shalini A , Bammer Roland , Maingard Julian 
Published: August 2020

AbstractIntroductionAustralia has fortunately had a low prevalence coronavirus disease 2019 (COVID‐19), and our healthcare system has not been overwhelmed. We aimed to determine whether, despite this, a decline in acute stroke presentations, imaging and intervention occurred during the pandemic at a busy stroke centre.MethodsThe number of ‘code stroke’ activations, multimodal CTs and endovascular clot retrievals (ECRs) performed during the pandemic period (3/1/2020–5/10/2020) at a large comprehensive stroke centre was compared against the pre‐pandemic period (3/1/2019–1/31/2019) using Z‐statistics. Year‐on‐year comparison of the number of patients with large vessel occlusions (LVOs) and ECRs performed per month was also made.ResultsThe number of ‘code stroke’ activations and patients undergoing multimodal CT per month decreased significantly (P < 0.0025) following lockdown on 29th March. The number of ECRs also decreased (P = 0.165). The nadir in the weekly number of CTs coincided with lockdown and the peak of new COVID‐19 cases. The number of patients with LVOs and ECRs increased by 15% and 14%, respectively, in March but decreased by 55% and 48%, respectively, in April.ConclusionsThe significant decrease in volume of ‘code stroke’ activations and acute stroke imaging following lockdown was accompanied by a concomitant decrease in patients with LVOs and ECRs. The decrease in imaging was therefore not driven purely by patients with mild strokes and stroke mimics, but also included those with severe strokes. Since Australia had a low prevalence of COVID‐19, this observed decrease cannot be attributed to hospital congestion and is instead likely driven by patient fear.
Law, Language, and a Nonsovereign Caribbean
Authors: Cabatingan Lee 
Published: August 2020

ABSTRACTThis article argues that the Caribbean Court of Justice (CCJ), a tribunal serving twelve independent primarily Anglophone Caribbean states, uses a variety of linguistic techniques in its pursuit of a regional future. Created upon a complicated (post)colonial landscape and charged with resolving the nonsovereignty of its member states, which, for the most part, continue to utilize the United Kingdom's Privy Council for their final court of appeal, the CCJ does not view sovereignty as a solution. Instead, as I demonstrate through several examples of the Court's use of, talk about, and abstention from language, the CCJ's judges and employees seek to constitute a yet‐to‐be‐fully‐defined nonsovereign region that carves out a Caribbean people, pointedly rejects ongoing British legacies and logics, refuses to adopt the legal practices associated with sovereignty, and strives to remain untethered to either nation‐state or suprastate. [law, language, sovereignty, region, Caribbean]
Full‐field electroretinography in age‐related macular degeneration: an overall retinal response
Authors: Forshaw Thomas Richard Johansen , Kjær Troels Wesenberg , Andréasson Sten , Sørensen Torben Lykke 
Published: August 2020

AbstractPurposeAge‐related macular degeneration (AMD) is generally considered a disease of the macula. However, recent studies show peripheral retinal lesions are prevalent in patients with AMD, indicative of a disease process that is more widespread. Full‐field electroretinography (ffERG) measures an electrical response, not only from the macula, but from the entire retina. We wanted to study the ffERG response in eyes with AMD.MethodsWe performed full‐field electroretinography (RETI‐port/scan 21, Roland, Berlin) in 13 patients with early AMD, 25 patients with late AMD and 24 individuals without vitreoretinal disease as a control group. Dawson–Trick–Litzkow fibre electrodes were used. Statistical analysis was performed and a p‐value <0.05 was considered significant.ResultsAfter adjusting for multiple comparisons, both the light‐adapted 3.0 a‐wave implicit time (p < 0.001) and 30‐Hertz flicker peak time (p = 0.012) showed significant difference between patients with late AMD and individuals without vitreoretinal disease. There was a significant difference in the light‐adapted 3.0 a‐wave implicit time (p = 0.011) between patients with early AMD and the control group, but the difference in 30 Hz flicker peak time was not significant (p = 0.256).ConclusionThe difference in cone function measured by light‐adapted 3.0 a‐wave implicit time and 30‐Hertz flicker peak time in early and late AMD when compared to healthy controls suggests a more diminished overall response when AMD has reached later stages.
Use of a physiologically based pharmacokinetic–pharmacodynamic model for initial dose prediction and escalation during a paediatric clinical trial
Authors: Johnson Trevor N. , Abduljalil Khaled , Nicolas Jean‐Marie , Muglia Pierandrea , Chanteux Hugues , Nicolai Johan , Gillent Eric , Cornet Miranda , Sciberras David 
Published: August 2020

AimsTo build and verify a physiologically based pharmacokinetic (PBPK) model for radiprodil in adults and link this to a pharmacodynamic (PD) receptor occupancy (RO) model derived from in vitro data. Adapt this model to the paediatric population and predict starting and escalating doses in infants based on RO. Use the model to guide individualized dosing in a clinical trial in 2‐ to 14‐month‐old children with infantile spasms.MethodsA PBPK model for radiprodil was developed to investigate the systemic exposure of the drug after oral administration in fasted and fed adults; this was then linked to RO via a PD model. The model was then expanded to include developmental physiology and ontogeny to predict escalating doses in infants that would result in a specific RO of 20, 40 and 60% based on average unbound concentration following a twice daily (b.i.d.) dosing regimen. Dose progression in the clinical trial was based on observed concentration–time data against PBPK predictions.ResultsFor paediatric predictions, the elimination of radiprodil, based on experimental evidence, had no ontogeny. Predicted b.i.d. doses ranged from 0.04 mg/kg for 20% RO, 0.1 mg/kg for 40% RO to 0.21 mg/kg for 60% RO. For all infants recruited in the study, observed concentration–time data following the 0.04 mg/kg and subsequent doses were within the PBPK model predicted 5th and 95th percentiles.ConclusionTo our knowledge, this is the first time a PBPK model linked to RO has been used to guide dose selection and escalation in the live phase of a paediatric clinical trial.
Surgical treatment of peri‐implantitis defects with two different xenograft granules: A randomized clinical pilot study
Authors: Polymeri Angeliki , Anssari‐Moin David , van der Horst Joyce , Wismeijer Daniel , Laine Marja L. , Loos Bruno G. 
Published: August 2020

AbstractObjectivesTo investigate whether xenograft EB (EndoBon) is non‐inferior to xenograft BO (Bio‐Oss) when used in reconstructive surgery of peri‐implant osseous defects.Materials and methodsDental patients with one implant each demonstrating peri‐implantitis were randomized to receive surgical debridement and defect fill with either BO or EB. Changes in bone level (BL) and intrabony defect depth (IDD) evaluated radiographically were the primary outcomes. The secondary outcomes included changes in probing pocket depth (PPD), bleeding on probing (BoP), and suppuration on probing (SoP). All outcomes were recorded before treatment and at 6 and 12 months post‐treatment.ResultsTwenty‐four patients (n = 11 BO,n = 13 EB) completed the study. Both groups demonstrated significant within‐group improvements in all clinical and radiographic parameters at 6 and 12 months (p ≤ .001). At 12 months, both groups presented with IDD reductions of 2.5–3.0 mm on average. The inter‐group differences were not statistically significant at all time points and for all the examined parameters (p > .05). While the radiographic defect fill in both groups exceeded > 1 mm and can be considered treatment success, successful treatment outcomes as defined by Consensus Reporting (no further bone loss, PPD ≤ 5 mm, no BOP, and no SoP) were identified in 2/11 (18%) BO and 0/13 (0%) EB individuals (Fisher's exact test,p = .199).ConclusionsWithin the limitations of this pilot study, the application of xenograft EB showed to be non‐inferior to xenograft BO when used in reconstructive surgery of peri‐implant osseous defects.
Berufsbedingte Allergie gegen Phytase: Fallserie von acht Produktionsmitarbeitern, die Futtermittelzusatzstoffen ausgesetzt waren
Authors: Kuske Marvin , Berndt Katja , Spornraft‐Ragaller Petra , Neumeister Volker , Raulf Monika , Sander Ingrid , Koschel Dirk , Bickhardt Jakob , Beissert Stefan , Bauer Andrea 
Published: August 2020

ZusammenfassungHintergrundIn der landwirtschaftlichen Fleischproduktion ist der Zusatz von Enzymen wie Phytase zu Tierfutter weit verbreitet, aber es gibt nur wenig Bewusstsein über das allergene Potenzial und die Gesundheitsrisiken dieser Pilzenzyme.Patienten und MethodenWir berichten über acht Patienten, die in einem Betrieb arbeiten, der Phytase‐Granulat herstellt. Alle Patienten litten an einer berufsbedingten Rhinitis, die sechs Monate nach Beginn der Exposition gegenüber Phytase‐Staub auftrat. Asthmatische Symptome und Kontakturtikaria traten ebenfalls auf. Anhand von Prick‐, Epikutan‐ und Basophilenaktivierungstests, die mit dem Fabrikprodukt durchgeführt wurden, konnten wir eine Sensibilisierung gegen Phytase nachweisen. Außerdem wurden die IgE‐ und IgG‐Antikörper gegen Phytase bestimmt.ErgebnisseSieben der acht Patienten zeigten im Pricktest eine positive Reaktion auf Phytase. Bei vier der acht Patienten wurde Phytase‐spezifisches IgE und bei sechs der acht Patienten Phytase‐spezifisches IgG nachgewiesen. Während der Basophilenaktivierungstest bei vier von sieben Patienten positiv ausfiel, war der Epikutantest bei allen getesteten Patienten negativ. Die Versetzung an einen anderen Arbeitsplatz ohne Exposition gegenüber Phytase führte zur vollständigen Rückbildung der Symptome.SchlussfolgerungenEnzyme von Schimmelpilzen wie Phytase sind hochwirksame Berufsallergene. Zum Gesundheitsschutz der Beschäftigten ist die konsequente Umsetzung von Arbeitsschutzmaßnahmen essentiell.