bluuebunny/crossref_metadata_2025_split huggingface dataset:
A New Concept for the Treatment and Rehabilitation of Patients with Pathologic Comorbidities Using Cutting-Edge Digital Technologies in Dental Orthopaedics
Authors: Yumashev Alexey V. , Mikhailova Maria V. , Fomin Igor V. , Li Jiaqi , Yang Bowen 
Published: July 2020

AbstractObjectives This article investigates the specific aspects of overactive or exaggerated vomiting reflexes affecting the procedure of dental examination and impression in patients with complete secondary adentia, who need orthopaedic dental treatment.Materials and Methods The prevailing manifestation degree of exaggerated vomiting reflex was diagnosed among patients with complete secondary adentia and exaggerated vomiting reflex.Statistical Analysis Exaggerated vomiting reflexes occur when a patient suffers from dentophobia, the term, which is otherwise known as the fear of dentists. The study was performed using methods of mathematical statistics, including the Pearson χ2 criterion and the statistical probability criterion (p).Results The role of an exaggerated vomiting reflex was revealed in the development of patients’ dentophobic experiences, and the nature of such experiences was established. Variations in dentophobic reactions were distinguished and management strategies were studied for patients with complete secondary adentia and exaggerated vomiting reflex.Conclusions These studies were aimed at preventing the development of vomiting reflex during dental procedures and at identifying an optimal strategy for stopping exaggerated vomiting reflex. The role of the vomiting reflex in the orthopaedic treatment of dental patients was determined.
Bilateral Proptosis in a Child—A Rare Manifestation of Ventriculoperitoneal Shunt Obstruction
Authors: Verma Deepti , Low David Chyi Yeu , Lim Joel Kian Boon 
Published: July 2020

AbstractVentriculoperitoneal shunt (VPS) obstruction may have a myriad of presentations. We reported a case of an 11-year-old girl presenting with acute, bilateral proptosis secondary to VPS obstruction. While neuroimaging was interpreted as unremarkable, fundoscopy revealed bilateral papilledema and lumbar puncture showed elevated intracranial pressure. Neurosurgical exploration demonstrated VPS valve obstruction and a new VPS was inserted. Postoperatively, she developed a recurrent extradural hematoma, which was initially evacuated and later managed conservatively. To our knowledge, this is the first report of bilateral proptosis secondary to VPS obstruction. This case highlights the value of key clinical findings and limitations of neuroimaging.
Predicting Lipid-Lowering Medication Persistence after the First Cardiovascular Disease Hospitalization
Authors: Hu Feiyu , Warren Jim , Exeter Daniel J. 
Published: July 2020

Abstract
Objectives This study analyzed patient factors in medication persistence after discharge from the first hospitalization for cardiovascular disease (CVD) with the aim of predicting persistence to lipid-lowering therapy for 1 to 2 years.
Methods A subcohort having a first CVD hospitalization was selected from 313,207 patients for proportional hazard model analysis. Logistic regression, support vector machine, artificial neural networks, and boosted regression tree (BRT) models were used to predict 1- and 2-year medication persistence.
Results Proportional hazard modeling found significant association of persistence with age, diabetes history, complication and comorbidity level, days stayed in hospital, CVD diagnosis type, in-patient procedures, and being new to therapy. BRT had the best predictive performance with c-statistic of 0.811 (0.799–0.824) for 1-year and 0.793 (0.772–0.814) for 2-year prediction using variables potentially available shortly after discharge.
Conclusion The results suggest that development of a machine learning-based clinical decision support tool to focus improvements in secondary prevention of CVD is feasible.
Effect of Hydrogel-Based Antibiotic Intracanal Medicaments on Push-Out Bond Strength
Authors: Yaghmoor Rayan B. , Platt Jeffrey A. , Spolnik Kenneth J. , Chu Tien Min Gabriel , Yassen Ghaeth H. 
Published: July 2020

Abstract
Objective This study aimed to evaluate the effects of typical clinical concentration (1,000 mg/mL), low concentration (1 mg/mL) triple antibiotic pastes (TAP), and double antibiotic pastes (DAP) on the bond strength between various root cements and radicular dentin.
Materials and Methods Intact single-rooted human teeth (n = 144) were horizontally decoronated and canals instrumented. The roots were treated for 4 weeks with Ca(OH)2, 1,000 mg/mL of TAP or DAP, and 1 mg/mL of TAP or DAP. Untreated roots served as a control. After treatment, the medicaments were irrigated and each group was divided into three subgroups receiving MTA, Biodentine, or Endosequence putty cement. After 2 weeks, coronal and middle root cylinders were obtained from each root. Push-out bond strength test and failure analysis were performed for all root cylinders.
Statistical Analysis  Three-way ANOVA, pairwise comparisons and logistic regression were used for statistical analyses. A significance level of 5% was used.
Results  For MTA applied in the coronal part of the roots, 1 mg/mL DAP and TAP and Ca(OH)2 demonstrated significantly higher bond strength compared with the typical clinical concentration and the control groups. For Biodentine applied coronally in the roots, 1 mg/mL of DAP resulted in significantly higher bond strength than all other groups. For Endosequence putty cement applied coronally in the roots, 1 mg/mL of DAP offered significantly higher bond strength than all groups except for Ca(OH)2.
Conclusion The use of 1 mg/mL DAP resulted in significantly higher push-out bond strength compared with the typical clinical concentration of TAP and DAP regardless of the type of the root cement used.
GATA4 Deletions Associated with Congenital Heart Diseases in South Brazil
Authors: Floriani Maiara A. , Glaeser Andressa B. , Dorfman Luiza E. , Agnes Grasiela , Rosa Rafael F. M. , Zen Paulo R. G. 
Published: July 2020

AbstractThe normal development of the heart comprises a highly regulated machinery of genetic events, involving transcriptional factors. Congenital heart disease (CHD), have been associated with chromosomal abnormalities and copy number variants (CNVs). Our goal was to investigate through the multiplex ligation-dependent probe amplification (MLPA) technique, the presence of CNVs in reference genes for normal cardiac development in patients with CHD. GATA4, NKX2–5, TBX5, BMP4, and CRELD1 genes and 22q11.2 chromosome region were analyzed in 207 children with CHD admitted for the first time in a cardiac intensive care unit from a pediatric hospital. CNVs were detected in seven patients (3.4%): four had a 22q11.2 deletion (22q11DS) (1.9%), two had a GATA4 deletion (1%) and one had a 22q11.2 duplication (0.5%). No patients with CNVs in the NKX2–5, TBX5, BMP4, and CRELD1 genes were identified. GATA4 deletions appear to be present in a significant number of CHD patients, especially those with septal defects, persistent left superior vena cava, pulmonary artery abnormalities, and extracardiac findings. GATA4 screening seems to be more effective when directed to these CHDs. The investigation of CNVs in GATA4 and 22q11 chromosome region in patients with CHD is important to anticipating the diagnosis, and to contributing to family planning.
Large Mesenteric Gaucheroma Responds to Substrate Reduction Therapy: A New Management of Gaucheromas
Authors: Yano Shoji , Moseley Kathryn , Mahajan Neha , Warren Mikako , Vachon Linda 
Published: July 2020

AbstractGaucheromas, which are pseudotumors consisting of a cluster of Gaucher cells, are rare complications in Gaucher's disease (GD) and reported in patients treated with enzyme replacement therapy (ERT). Gaucheromas commonly develop in the lymph nodes in the mesenteric and mediastinal regions and can cause serious complications including protein-losing enteropathy. A large mesenteric Gaucheroma showed a significant reduction in size after initiation of substrate reduction therapy (SRT) with eliglustat in an adult patient with GD type 3. Combination therapy with ERT and SRT should be considered to prevent Gaucheromas in patients with GD.
Two Novel Compound Heterozygous ADGRG1/GPR56 Mutations Associated with Diffuse Cerebral Polymicrogyria
Authors: Jha Ruchika , Kovilapu Uday B. , Devgan Amit , Sondhi Vishal 
Published: July 2020

Abstract
Background Polymicrogyria (PMG) has environmental or genetic etiologies. We report a 8-year-old boy with diffuse PMG and two novel adhesion G protein-coupled receptor G1 (ADGRG1)/G protein-coupled receptor 56 (GPR56) mutations.
Case Report The proband has intellectual disability, spastic quadriparesis, and intractable epilepsy without antenatal or perinatal insults. Brain magnetic resonance imaging revealed PMG involving fronto-polar, parietal and occipital lobes with decreasing antero-posterior gradient, and a thinned-out brain stem. Targeted exome sequencing identified two novel compound heterozygote ADGRG1/GPR56 mutations (c.C209T and c.1010dupT), and each parent carries one of these mutations. Subsequent pregnancy was terminated because the fetus had the same mutations.
Conclusion The detected mutations expanded the genetic etiology of PMG and helped the family to avoid another child with this devastating condition.
A spatial minimum spanning tree filter
Authors: Jin Yusheng , Zhao Hong , Gu Feifei , Bu Penghui , Na Mulun 
Published: July 2020

Abstract
It is well-known that the minimum spanning tree (MST) is widely used in image segment, edge-preserving filtering, and stereo matching. However, the non-local (NL) filter based on the MST generally results in overly smooth images, since it ignores spatial affinity. In this paper, we propose a new spatial minimum spanning tree filter (SMSTF) to improve the performance of the NL filter by designing a spatial MST to avoid over-smoothing problems, by introducing recursive techniques to implement the filtering process. The SMSTF has the advantages that: (1) the kernel of our filter considers spatial affinity and similarity of intensity; (2) The size of the filter kernel is the entire image domain; (3) the complexity of the SMSTF is linear to the number of image pixels. For these reasons, our filter achieves excellent edge-preserving results. Extensive experiments demonstrate the versatility of the proposed method in a variety of image processing and computer vision tasks, including edge-preserving smoothing, stylization, colorization, and stereo matching.
A deep neural network for estimating the bladder boundary using electrical impedance tomography
Authors: Konki S K , Khambampati A K , Sharma S K , Kim K Y 
Published: July 2020

Abstract

Objective: Accurate bladder size estimation is an important clinical parameter that assists physicians, enabling them to provide better treatment for patients who are suffering from urinary incontinence. Electrical impedance tomography (EIT) is a non-invasive medical imaging method that estimates organ boundaries assuming that the electrical conductivity values of the background, bladder, and adjacent tissues inside the pelvic domain are known a priori. However, the performance of a traditional EIT inverse algorithm such as the modified Newton–Raphson (mNR) for shape estimation exhibits severe convergence problems as it heavily depends on the initial guess and often fails to estimate complex boundaries that require greater numbers of Fourier coefficients to approximate the boundary shape. Therefore, in this study a deep neural network (DNN) is introduced to estimate the urinary bladder boundary inside the pelvic domain. Approach: We designed a five-layer DNN which was trained with a dataset of 15 subjects that had different pelvic boundaries, bladder shapes, and conductivity. The boundary voltage measurements of the pelvic domain are defined as input and the corresponding Fourier coefficients that describe the bladder boundary as output data. To evaluate the DNN, we tested with three different sizes of urinary bladder. Main results: Numerical simulations and phantom experiments were performed to validate the performance of the proposed DNN model. The proposed DNN algorithm is compared with the radial basis function (RBF) and mNR method for bladder shape estimation. The results show that the DNN has a low root mean square error for estimated boundary coefficients and better estimation of bladder size when compared to the mNR and RBF. Significance: We apply the first DNN algorithm to estimate the complex boundaries such as the urinary bladder using EIT. Our work provides a novel efficient EIT inverse solver to estimate the bladder boundary and size accurately. The proposed DNN algorithm has advantages in that it is simple to implement, and has better accuracy and fast estimation.
Multilevel memristive non-volatile look-up table using two transmission gates one memristor memory cells
Authors: Ian Wong C W , Ho Patrick W C 
Published: July 2020

Abstract
Memory structures can be found in most electronic devices ranging from field programmable gate arrays to smart devices. There is an increasing demand for these devices to be energy efficient, small, fast and have high density for storage. Memory devices such as the static random access memory (SRAM) are widely used in many electronic devices, however SRAMs have a volatile memory architecture. A memristor is a unique electronic component with binary memory capabilities that are non-volatile which could replace the conventional memory cell architectures. This paper proposes the use of memristors in a quaternary 2-bit multileveled memory cell as a non-volatile look-up table (MNVLUT). The MNVLUT uses a dynamic ground with two transmission gates one memristor architecture with Schmitt triggers for the read and write operations. The proposed MNVLUT achieves lower energy consumption and writing time when compared to other existing memory architectures.
Experimental validation of solar panel integrated modified three-port active clamp flyback converter fed micro-inverter
Authors: Kumarasabapathy N , Manoharan P S , Ramasamy M 
Published: July 2020

Abstract
In this paper, a photovoltaic (PV) tied modified three-port active flyback converter (MTPACFC) operated three-phase micro-inverter is presented to provide enhanced voltage gain with fewer components. The proposed micro-inverter transfers the power generated on the 12 V PV power generation system to 400 V, AC grid. Generally, the DC-DC converter designed with an active clamp circuit provides improved power transfer capability to transfer the power from the PV array. The conventional active clamp flyback converters are designed to offer a limited boost factor for the input voltage. The recommended three-port altered flyback converter is intended to offer double boosting for the input voltage with extended performance. Besides, a synchronous reference frame theory with an artificial neural network based grid side controller is adapted to provide low total harmonic distortion at the point of common coupling. The outcomes of the simulated and test models are introduced to approve the boosting capacity and performance of the proposed MTPACFC.
Photon blockade in a double-cavity optomechanical system with nonreciprocal coupling
Authors: Wang Dong-Yang , Bai Cheng-Hua , Liu Shutian , Zhang Shou , Wang Hong-Fu 
Published: July 2020

Abstract
Photon blockade is an effective way to generate single photon, which is of great significance in quantum state preparation and quantum information processing. Here we investigate the statistical properties of photons in a double-cavity optomechanical system with nonreciprocal coupling, and explore the photon blockade in the weak and strong coupling regions respectively. To achieve the strong photon blockade, we give the optimal parameter relations under different blockade mechanisms. Moreover, we find that the photon blockades under their respective mechanisms exhibit completely different behaviors with the change of nonreciprocal coupling, and the perfect photon blockade can be achieved without an excessively large optomechanical coupling, i.e., the optomechanical coupling is much smaller than the mechanical frequency, which breaks the traditional cognition. Our proposal provides a feasible and flexible platform for the realization of single-photon source.
Orthogonal Optimization Design of Scour Protection Device with Flexible Material for Pile Foundation
Authors: Wang Tianying , Zhou Yanjun , Tang Honglin , Tian Haiqing 
Published: July 2020

Abstract
To apply the scour protection device with the flexible material developed by the author to engineering practice, orthogonal optimization design of the device for a fixed offshore platform in Chengdao Oilfield as a case study was presented. The influences of main design parameters, such as pile diameter, thickness of flexible material and elastic modulus of flexible material on the protective effect of the device were studied by two-way fluid-solid interaction numerical simulation based on ANSYS workbench platform. Then, the optimal design plan of the scour protection device with flexible material was determined. Furthermore, by comparing and contrasting the results of the flow field calculation for the pile legs with versus without protective devices were compared and analysed, the device’s good effective protection effect functionality was demonstrated. The research results will shed light on the practical engineering design of the flexible energy dissipation guiding antiscour device.
Permeability of A Composite Seawall: Effect of the Orientation of Gaps in the Structure
Authors: Dabir Vaishnavi , Deki Sonam , Agarwal Kunal , Ranjan Ashish , Khare Kanchan 
Published: July 2020

Abstract
A Seawall requires reflecting and dissipating entire wave energy with zero transmission. The permeability would significantly affect its hydraulic stability under wave loads. Thus, the permeability of a structure changes with the material and consequently a variation in the composite structure may give a different perspective on the hydraulic performance of a seawall altogether. As a first step towards establishing the composite seawall, a comprehensive permeability test is performed as a preliminary assessment of hydraulic conductivity. In the current research, a bag made of non-woven geotextile polymer filled with sand and a roll of non-woven needle punched coir geotextile is investigated. A total number of 20 model tests were performed by varying the orientation and positions of the material composites and thereby the gaps in the structure. The results are noted and future research possibilities into the design and development of a composite seawall as an alternative to traditional seawall are thus presented.
Dynamic Response Computation of Single-Point Mooring of Product Tanker Based on AQWA
Authors: Zhang Xuan , Hu Jinpeng , Hong Bo 
Published: July 2020

Abstract
This paper took the product tanker at sea and its mooring positioning system as the research object and used the time-frequency domain method to calculate the movement of the product tanker. In the three-dimensional potential flow theory, a single-point mooring system was established as a numerical model in the ANSYS Workbench. The frequency-domain computing module was to analyze the hydrodynamic response of the tanker under the unit regular waves, the dynamic response amplitude operators (RAOs) of the tanker, and the motion conditions under different frequency distributions. The time-domain computing module was to analyze the response of a single-point mooring system under the actions of wind, wave, and current. Setting the mooring point, pretension, layout, mooring radius, and other parameters, of the mooring product tanker was calculated lasted 1 hour for the time-domain coupling analysis under the extreme offshore environment. The tension of each cable was compared with the minimum breaking strength of the mooring cable to determine its safety.
Study on Design Strategies About Single-sided Natural Ventilation in Residential Buildings
Authors: Lei Jingbo , Chen Hong , Song Risheng 
Published: July 2020

Abstract
Natural ventilation is an effective measure to reduce energy consumption and improve indoor environment. The enlargement of the depth of high-rise residential buildings allows only single-sided natural ventilation, which makes the problem of poor natural ventilation itself more serious. In this study, CFD numerical analysis was used to verify the optimal design strategy of one-sided ventilation residence in a practical case, and the results showed that the design strategy could improve the ventilation effect of one-sided ventilation houses [1].
Pore type characterization of kais carbonate reservoir using differential effective medium
Authors: Prananda A , Rosid M S , Widodo R W 
Published: July 2020

Abstract
The Kais Formation is a hydrocarbon reservoir that produces in the Salawati Basin. However, the success in drilling has diminished so a new concept of exploration is needed to characterizing the pore type. Carbonate reservoirs are classified into three pore types based on pore geometry, namely interparticle pore, stiff pore, and crack pore. The pore geometry of carbonate reservoir is very complicated which is compared to siliciclastic rock. The process has greatly affects heterogeneity and pore geometry complexity are cementation, dissolution, and fracturing. These processes modify the pore geometry which correlates with rock porosity. The modification of pore geometry will change the rock elastic properties. It can be identified from the P-wave velocity (Vp). The change in P-wave velocity (Vp) has an effect of 40 %, as a result of modification of the pore geometry. Therefore, studies of rock physical properties that take into account the complexity of pore geometry are very important in characterizing carbonate rocks. Differential Effective Medium (DEM) is one of the elastic rock modeling methods which calculates the geometry aspect of the pore by including porosity into the parent material. The aim of this study is to characterize pore type using DEM in the three different wells; MEI-1 well, MEI-2 well, and APR-1 well. The result of this study shows that MEI-1 and APR-1 well is dominated by interparticle and crack pore, while MEI-2 well is dominated by interparticle and stiff pore.