bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evidenciación contable de las organizaciones sin fines lucrativos de asistencia social en Feira de Santana (BA): enfoque de acuerdo con las normas brasileñas de contabilidad
Authors: Acmar Feliz dos Santos de Santana  , Tânia Cristina Azevedo  
Published: January 2020

Objetivo: el trabajo tenía como objetivo analizar la conformidad de la divulgación contable de las Organizaciones sin Ánimo de Lucro (en Brasil OSFL), poseedoras del Certificado de Entidad Benéfica de Asistencia Social (CEBAS) en Feira de Santana (BA), de acuerdo con las Normas Brasileñas de Contabilidad, y mediante la adopción de la Interpretación Técnica General – ITG 2002 (R1).
Metodología: se trata de un estudio cualitativo en cuanto al enfoque, realizado por medio de la investigación bibliográfica y documental. La etapa empírica de la investigación se realizó mediante un levantamiento de datos de las Entidades de Asistencia Social registradas en la página web del Ministerio de Desarrollo Social (MDS), seguido de la recogida de la información contable que allí se divulga y utilizando la estadística descriptiva para el tratamiento de los datos.
Resultados: la investigación demostró que el nivel de atención a la ITG 2002 (R1) puede ser considerado razonable, no obstante, los hallazgos de la investigación revelan que las áreas de gestión administrativo-financiera de las Entidades Benéficas de Asistencia Social (EBAS) no priorizan la elaboración y divulgación de la información contable para ser usada o para rendir cuentas a usuarios diversos.
Contribuciones del estudio: la contribución de la presente investigación reside en su fuente que está inspirada en las prácticas contables previstas en la ITG 2002 (RI) adoptadas por las EBAS, propiciando así el avance de futuras investigaciones en entidades que actúan en otros sectores.
Novel Thiazole-Based Thiazolidinones as Potent Anti-infective Agents: In silico PASS and Toxicity Prediction, Synthesis, Biological Evaluation and Molecular Modelling
Authors: Tratrat Christophe 
Published: January 2020

Aims and Objective:
The infectious disease treatment remains a challenging concern
owing to the increasing number of pathogenic microorganisms associated with resistance to
multiple drugs. A promising approach for combating microbial infection is to combine two or more
known bioactive heterocyclic pharmacophores in one molecular platform. Herein, the synthesis
and biological evaluation of novel thiazole-thiazolidinone hybrids as potential antimicrobial agents
were dissimilated.

Materials and Methods:
The preparation of the substituted 5-benzylidene-2-thiazolyimino-4-
thiazolidinones was achieved in three steps from 2-amino-5-methylthiazoline. All the compounds
have been screened in PASS antibacterial activity prediction and in a panel of bacteria and fungi
strains. Minimum inhibitory concentration and minimum bacterial concentration were both
determined by microdilution assays. Molecular modeling was conducted using Accelrys Discovery
Studio 4.0 client. ToxPredict (OPEN TOX) and ProTox were used to estimate the toxicity of the
title compounds.

Results:
PASS prediction revealed the potentiality antibacterial property of the designed thiazolethiazolidinone
hybrids. All tested compounds were found to kill and to inhibit the growth of a vast
variety of bacteria and fungi, and were more potent than the commercial drugs, streptomycin,
ampicillin, bifomazole and ketoconazole. Further, in silico study was carried out for prospective
molecular target identification and revealed favorable interaction with the target enzymes E. coli
MurB and CYP51B of Aspergillus fumigatus. Toxicity prediction revealed that none of the active
compounds was found toxic.

Conclusion:
Substituted 5-benzylidene-2-thiazolyimino-4-thiazolidinones, endowing remarkable
antibacterial and antifungal properties, were identified as a novel class of antimicrobial agents and
may find a potential therapeutic use to eradicate infectious diseases.
Determination and Modeling on Ultraviolet Light Degradation of Pyridaben Based on Fluorescence Spectrum
Authors: Ji Rendong , Ma Shicai , Bian Haiyi , Wang Xiaoyan , Yu Chenyue , Zhang Yulin 
Published: January 2020

Aim and Objective:
Pesticide residues seriously affect human health, so it is very important to
study the degradation of pesticide residues for food safety. The degradation of pyridaben by ultraviolet
(UV) irradiation was studied, the degradation characteristics and modeling were analyzed in this paper.
This study was undertaken to fully reveal the degradation mechanism of UV irradiation for pyridaben
residue and provided the evaluation method of degradation effect.

Materials and Methods:
Firstly, the fluorescence spectra of pyridaben samples were measured by LS55
fluorescence photometer, and the relationship between pyridaben concentration and the fluorescence
intensity of characteristic peak was established. Then, using UV irradiation approach, the pyridaben was
degraded to different degrees by controlling the irradiation time. The degradation process was
characterized according to the change of fluorescence characteristic peak intensity before and after
degradation. The relationship between degradation time and fluorescence intensity was established at last.

Results:
The results showed that the fluorescence characteristic peak of pyridaben was located at 356 nm.
The pyridaben content prediction model function was obtained with the correlation coefficient of 0.9989
and the average recovery of 99.70%. The relative standard deviation (RSD%), the limit of detection (LOD)
and the limit of quantity (LOQ) was 1.71%, 0.0058 ug/ml and 0.0193 ug/ml, respectively. The exponential
function model between UV degradation time and fluorescence intensity was obtained, the corresponding
correlation coefficient was 0.9991, and the average recovery was 100.49%.

Conclusion:
UV light irradiation can effectively degrade pyridaben, degradation process can be
characterized by the change of fluorescence intensity, and the degradation model was tested to be accurate.
Access to a Library of 1,3-disubstituted-1,2,3-triazenes and Evaluation of their Antimicrobial Properties
Authors: Seck Insa , Ndoye Samba F. , Ba Lalla A. , Fall Alioune , Diop Abdoulaye , Ciss Ismaïla , Ba Abda , Sall Cheikh , Diop Amadou , Boye Cheikh S. , Gomez Generosa , Fall Yagamare , Seck Matar 
Published: January 2020

Background:
Due to the rapid development of microbial resistance, finding new molecules
became urgent to counteract this problem.

Objective:
The objective of this work is to access 1,2,3-triazene-1,3-disubstituted, a class of molecule with
high therapeutic potential.

Methods:
Here we describe the access to 17 new triazene including six with an imidazole-1,2,3-triazene
moiety and eleven with an alkyl-1,2,3-triazene moiety and their evaluation against five strains: two
gram (-): Escherichia coli ATCC 25921 and Pseudomonas aeruginosa ATCC 27253; two gram (+) :
Staphylococcus aureus ATCC 38213 and Enterococcus faecalis ATCC 29212; and one fungi: Candida
albicans ATCC 24433.

Results:
All strains were sensitive and the best MIC, 0.28 µM, is observed for 4c against Escherichia
coli ATCC 25921. Compound 9, 3-isopropynyltriazene, appears to be the most interesting since it is
active on the five evaluated strains with satisfactory MIC 0.32 µM against Escherichia coli and Pseudomonas
aeruginosa and 0.64 µM against Enterococcus faecalis and Pseudomonas aeruginosa.

Conclusion:
Comparing the structure activity relationship, electron withdrawing groups appear to increase
antimicrobial activity.
Chemometrics-assisted Spectrophotometric Method for Simultaneous Estimation of Antipsychotic Drugs in Biological Fluid
Authors: Alibakhshi Mojdeh , Sohrabi Mahmoud Reza , Davallo Mehran 
Published: January 2020

Background:Haloperidol (HP) and Risperidone (RIS) are antipsychotic drugs and the simultaneous determination of these drugs is important. Estimation of HP and RIS alone or in combination with other drugs has been performed in a variety of ways.Objective:The aim of this paper was to propose a rapid, simple, accurate, and robust method for the simultaneous determination of HP and RIS using Artificial Neural Networks (ANNs), Partial Least Squares (PLS), and Principal Component Regression (PCR) methods along with spectrophotometry technique.Methods:The simultaneous spectrophotometric determination of HP and RIS in synthetic mixtures and biological fluid was performed by applying ANNs Containing Feed-forward Backpropagation (FFBP) and Radial Basis Function (RBF) networks as intelligent methods, as well as PLS, and principal component regression PCR as multivariate calibration methods. The Levenberg- Marquardt (LM), Scaled Conjugate Gradient (SCG), and Resilient Back-propagation (RP) algorithms with different layers and neurons were used in FFBP network and obtained results were compared with each other.Results:Among various algorithms of the FFBP network, the LM algorithm was selected as the best model with a lower Mean Square Error (MSE). MSE of the RBF model was 1.46×10-25and 1.62×10-23for HP and RIS, respectively. On the other hand, the mean recovery of PLS and PCR was 99.91%, 100.01% and 98.60%, 101.90% for HP and RIS, respectively.Conclusion:The proposed models and High-Performance Liquid Chromatography (HPLC) as a reference method were compared with each other by one-way Analysis of Variance (ANOVA) test at the 95 % confidence level for the urine sample. It was observed that the developed methods presented comparable results for the simultaneous determination of HP and RIS.
Formalization and Semantic Integration of Heterogeneous Omics Annotations for Exploratory Searches
Authors: Irshad Omer , Ghani Khan Muhammad Usman 
Published: January 2020

Aim:
To facilitate researchers and practitioners for unveiling the mysterious functional aspects of human cellular system through performing exploratory searching on semantically integrated heterogeneous and geographically dispersed omics annotations.

Background:
Improving health standards of life is one of the motives which continuously instigates researchers and practitioners to strive for uncovering the mysterious aspects of human cellular system. Inferring new knowledge from known facts always requires reasonably large amount of data in well-structured, integrated and unified form. Due to the advent of especially high throughput and sensor technologies, biological data is growing heterogeneously and geographically at astronomical rate. Several data integration systems have been deployed to cope with the issues of data heterogeneity and global dispersion. Systems based on semantic data integration models are more flexible and expandable than syntax-based ones but still lack aspect-based data integration, persistence and querying. Furthermore, these systems do not fully support to warehouse biological entities in the form of semantic associations as naturally possessed by the human cell.

Objective:
To develop aspect-oriented formal data integration model for semantically integrating heterogeneous and geographically dispersed omics annotations for providing exploratory querying on integrated data.

Method:
We propose an aspect-oriented formal data integration model which uses web semantics standards to formally specify its each construct. Proposed model supports aspect-oriented representation of biological entities while addressing the issues of data heterogeneity and global dispersion. It associates and warehouses biological entities in the way they relate with

Result:
To show the significance of proposed model, we developed a data warehouse and information retrieval system based on proposed model compliant multi-layered and multi-modular software architecture. Results show that our model supports well for gathering, associating, integrating, persisting and querying each entity with respect to its all possible aspects within or across the various associated omics layers.

Conclusion:
Formal specifications better facilitate for addressing data integration issues by providing formal means for understanding omics data based on meaning instead of syntax
A Short Scale Trial to Study and Evaluate the Safety and Efficacy of a Herbal Composition; Verona Anti-BPH Capsule to Treat Benign Prostatic Hyperplasia in Men Older than 40 Years of Age
Authors: Hasan Ifrah , Naqvi Saba Fatima , Khan Amraa , Hasan Yamna , UzairUllah Mir 
Published: January 2020

Aims and objective:Benign Prostatic Hyperplasia (BPH) is a condition that causes the proliferation of the cells of the prostate causing urine retention, renal insufficiency, bladder calculi, recurrent Lower Urinary Tract Infections (LUTS) and in complicated cases, hematuria with unbearable pain. The trial was conducted to study the safety and efficacy of novel herbal product Verona anti- BPH capsules at a local clinic of Sharafi Goth, Karachi Pakistan.Introduction:Benign Prostatic Hyperplasia (BPH) is one major condition. The prevalence of the disease increases to around 8-60% in men at the age of 40 years which is caused mainly by hormonal change, lifestyle changes or diet. The disease is mainly defined as increased cellular proliferation of the prostate glands or an enlarged prostate. 50% men of age 65 years and above of the total population of Pakistan are at risk of having Benign Prostatic Hyperplasia (BPH).Method:This was a single blind, placebo control phase I clinical trial. A total of 35 patients were enrolled in the study, out of which 2 patients got dropped out. 23 patients received Verona anti-BPH capsules and 10 patients received placebo. The sample paired t-test was applied to evaluate the significant level.Results:Verona Anti-BPH capsules were found safe and effective in the treatment of Benign Prostatic Hyperplasia (anti-BPH).Conclusion:Verona anti-BPH capsules were known to be effective with no harmful side effects.
Texto literário e modos de organização do discurso: uma análise semiolinguística do conto fantástico 'Sonata', de Erico Verissimo
Authors: Moreira Jorge de Azevedo 
Published: January 2020

Propomos um estudo relacionando as características do gênero literário fantástico aos modos de organização do discurso, de acordo com a teoria semiolinguística de Patrick Charaudeau. Segundo Tzvetan Todorov, o fantástico caracteriza-se pelo efeito de hesitação produzido no texto. Torna-se importante examinar, então, de que modo esse efeito se insere nos modos de organização narrativo e descritivo. Utilizaremos o conto Sonata, de Erico Verissimo, a fim de ilustrar nossas ideias a esse respeito.
PROJECT-BASED LEARNING APPROACH TO IMPROVE STUDENTS’ WRITING SKILL
Authors: Zulaeha Dedeh Eha , Marpaung Dian Priyantini 
Published: January 2020

This research was held during the internship at SMPK BPK PENABUR Cimahi by taking the material taught in English lesson for 8th grade students at first semester. The objective of this research is to find out the improvement of writing imperative sentence using Project-Based Learning approach. The use of Project Based Learning approach suited with the Kurikulum 2013, which has been used by this school since 2013. The method used Classroom Action Research (CAR), which held on two cycles for seven meetings. Each cycle covered the step of planning, acting, observing and reflecting. The data was collected from test and observation. The data from test showed that treatments are successful in improving writing imperative sentences skill for the students. The improvements covered two points, (1) improvement on their mean score. Mean score of pre-test was 54.967, mean score of post-test1was 64.467 and mean score of post-test2 was 80.033. (2) Improvement of their behaviors. Their activeness individually and participation in the group indicated that the Project Based Learning approach was the right approach to be applied in the classroom teaching. Keywords: CAR, Project-Based Learning Approach, Writing Skill
THE USE OF CLUSTERING TECHNIQUE TO IMPROVE STUDENTS’ SKILL IN WRITING DESCRIPTIVE TEXT
Authors: Hanafiawi Della , Muharam Harry , Parmawati Aseptiana 
Published: January 2020

Students have to learn the four basic language skill, they are listening, reading, writing, speaking. One of the most important skill that is Writing. It can make students to share the ideas into written form in the text or paragraph with the right order of generic structure. The purpose of this research was to find out the improving of students writing skill of descriptive text using clustering technique at seventh grade students of SMPN 11 Cimahi in the Academic Year of 2018 – 2019. This research used Classroom Action Research. The research was carried out in two cycles and each cycle consisted of four steps, they are Planning, Action, Observation, and Reflection. Most of the students gradually gained good scores at the end of each cycles. The students responses showed that they interested to learn writing.The score of Minimum Mastery Criterion of English lesson was 75. The Students mean score of pretest 45,7. The mean score in postest 1 was 53,7. The mean score of posttest 2 was 79,3. From this result, the researcher concludes that teaching descriptive text using clustering technique can improve their writing ability and the atmosphere of the class was more alive. Keywords: CAR, Writing Skill
A IMPORTÂNCIA DE ENSINAR RESISTÊNCIA BACTERIANA NO ENSINO MÉDIO: UMA ANÁLISE DE LIVROS DIDÁTICOS DE BIOLOGIA SELECIONADOS PELO PNLEM/2018
Authors: Alves Carvalho Marcelle , Sanches Pereira Carlos Alberto , Oliveira Souza Lidiane de Fátima de , Cunha Pereira Ana Paula 
Published: January 2020

O presente trabalho é fruto de uma pesquisa que investiga o tema da resistência bacteriana e suas relações com o campo do ensino e as discussões que tangem o tema da saúde, gerando o objetivo desta pesquisa: verificar o trato do tema resistência bacteriana, abordada em livros didáticos e sua explanação relativa a importância do uso correto de antibióticos. Para isso, lançamos mão de uma metodologia de cunho qualitativo, empreendendo um estudo descritivo de 10 (dez) livros didáticos de Biologia indicados pelo Programa Nacional do Livro Didático para o Ensino Médio (PNLEM/2018). A análise considerou a presença de quatro critérios: C1- doenças bacterianas e seu tratamento; C2- Resistência Bacteriana; C3- Problematização do tema Resistência Bacteriana; C4- Incentivo as práticas de uso correto de antibióticos. Dos livros analisados 80% estão adequados quanto ao ensino de doenças bacterianas e tratamento. O tema resistência bacteriana apareceu em 50% dos livros com tópicos extremamente pequenos e explicações rasas. A problematização da resistência bacteriana apareceu em 70% dos livros com número de questões insignificantes. O uso correto de antibióticos apareceu somente em 40% dos livros. Concluímos que se faz necessário a criação de outras formas didáticas para o ensino destas temáticas em sala de aula.
O PROCESSO INVESTIGATIVO-REFLEXIVO COMO PROPULSOR DA CONSTITUIÇÃO DOCENTE
Authors: Novakowski Kierepka Janice Silvana , Bremm Daniele , Costa Güllich Roque Ismael da 
Published: January 2020

O trabalho objetiva reconhecer o papel da reflexão e das narrativas no processo de constituição docente. Para tanto, foram analisados diários de formação de duas professoras de Ciências, que participam dos Ciclos Formativos em Ensino de Ciências e Matemática, projeto de extensão do Grupo de Estudos e Pesquisa em Ensino de Ciências e Matemática (GEPECIEM) da Universidade Federal da Fronteira Sul (UFFS) Campus Cerro Largo. Foi possível identificar avanços na formação dessas professoras à medida que se distinguem diferentes níveis de reflexão, o que vai gradativamente transformando teorias e práticas. Também foi possível identificar progressos ocorridos nas práticas pedagógicas, de uma perspectiva tradicional para a valorização da pesquisa em sala de aula, diversificando as metodologias empregadas, porém mantendo alguns aspectos da aula tradicional. As reflexões no diário de bordo propiciam a explicitação das concepções de docência, Ciência e de ensino de Ciências, o que implica um processo de transformação das teorias e práticas.
A REFORMA DO ENSINO MÉDIO POR MEIO DA LEI Nº 13.415/2017 E SEUS IMPACTOS NO ENSINO MÉDIO INTEGRADO DOS INSTITUTOS FEDERAIS
Authors: Santos Stering Silvia Maria dos , Mary Adam Joyce 
Published: January 2020

Este artigo evidencia os impactos da Reforma do Ensino Médio - REM no Ensino Médio Integrado - EMI nos Institutos Federais – IF`s via pesquisa qualitativa, bibliográfica e documental. Analisamos normativas e legislações que tratam dos itinerários formativos na Lei Nº 13.415/2017 em articulação com as reformas de cunho neoliberais que almejam reduzir gastos públicos e encaminhamento da classe trabalhadora para o mercado de trabalho, além de comparar com o fenômeno ocorrido no Chile na década de 80. O texto reflete as concepções de Educação Profissional e Tecnológica - EPT com foco na proposta de EMI, que demanda uma visão crítica sobre o contexto no qual o sujeito está inserido e busca na tecnologia a produção de conhecimentos que visem à formação integral. O estudo aponta que a lei não impactou a oferta dos cursos, uma vez que os IF`s não aderiram à mesma, tendo em vista que se destacam pela qualidade e condições de funcionamento necessárias à formação humana mediante integração entre ciência, tecnologia, cultura e trabalho como eixos norteadores do currículo. A REM consiste no fortalecimento da dualidade educacional e de uma orientação mercadológica; precarização da docência que não afetou os Institutos Federais, dado a sua condição de autarquia.
Politics and Literature English Literary Work as a Model
Authors: Blaiha Marouan 
Published: January 2020

This paper tries to tackle the political aspects in literature during the 19th century, and to reveal the political tendency in the literary work, which means shedding lights on the effect of the environments and the political atmospheres during the 19th century in shaping the aesthetic work.
On the other hand, the paper takes a specific literary work during this era and reveals its relation with the political events. In addition, we expostulate the strong relation-ship between the socio-economic status of the writer and literature. Meanwhile, the paper relies on the systematic analysis of the political scientist David Histon in explaining the issue in question. We are going to reveal this tendency in the second chapter.
A Study on Knowledge on Breastfeeding Practices in Rural Area
Authors: Rajalakshmi Dr. S. , Kalaivani Dr. P. 
Published: January 2020

Introduction
Breastfeeding is the universally accepted means of infant feeding. The World Health Organization (WHO) recommends exclusive breastfeeding for the first six months of life and thereafter continued breastfeeding until two years of age along with complementary feeds (WHO, 2009).
The Digital Economy
Authors: Bazzoun Mohammed 
Published: January 2020

Five major technology trends have collided to shape what is becoming known as the digital economy: Hyper-connectivity, supercomputing, cloud computing, cyber security, and smart products have created a world where the traditional boundaries of products vs. service offerings no longer exist. Individuals, businesses, and societies are connecting in real time, creating a world that is more collaborative, intelligent, and responsive.
Fortunately, the oil and gas industry has been highly automated and digitized for decades. Yet the technology powering the digital economy is taking connectivity to a new level, transforming nearly every aspect of operations and customer engagement. Early adopters are growing shareholder and stakeholder value faster than their peers while those failing to adapt are falling behind. Staying ahead of the curve means taking a hard look at existing practices and reimagining everything from business models and processes to work management solutions.