bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolomics window into the role of acute kidney injury after coronary artery bypass grafting in diabetic nephropathy progression
Authors: Wang Jiayi , Yan Wenzhe , Zhou Xiang , Liu Yu , Tang Chengyuan , Peng Youming , Liu Hong , Sun Lin , Xiao Li , He Liyu 
Published: May 2020

Introduction
Metabolomics has emerged as a valuable tool to discover novel biomarkers and study the pathophysiology of diabetic nephropathy (DN). However, the effect of postoperative acute kidney injury (AKI) on diabetes mellitus (DM) to chronic DN progression has not been evaluated from the perspective of metabolomics.

Methods
A group of type 2 diabetes mellitus (T2DM) inpatients, who underwent off-pump coronary artery bypass grafting (CABG), were enrolled in our study. According to whether postoperative AKI occurred, patients were grouped in either the AKI group (AKI, n = 44) or the non-AKI group (NAKI, n = 44). Urine samples were collected from these patients before and 24 h after operation. Six patients from the AKI group and six patients from the NAKI group were chosen as the pilot cohort for untargeted metabolomics analysis, with the goal of identifying postoperative AKI-related metabolites. To understand the possible role of these metabolites in the chronic development of renal injury among T2DM patients, trans-4-hydroxy-L-proline and azelaic acid were quantified by targeted metabolomics analysis among 38 NAKI patients, 38 AKI patients, 46 early DN patients (DN-micro group), and 34 overt DN patients (DN-macro group).

Results
Untargeted metabolomics screened 61 statistically distinguishable metabolites in postoperative urine samples, compared with preoperative urine samples. Via Venn diagram analysis, nine of 61 were postoperative AKI-related metabolites, including trans-4-hydroxy-L-proline, uridine triphosphate, p-aminobenzoate, caffeic acid, adrenochrome, δ-valerolactam, L-norleucine, 5′-deoxy-5′-(methylthio) adenosine, and azelaic acid. By targeted metabolomics analysis, the level of trans-4-hydroxy-L-proline increased gradually from the NAKI group to the AKI, DN-micro, and DN-macro groups. For azelaic acid, the highest level was found in the NAKI and DN-micro groups, followed by the DN-macro group. The AKI group exhibited the lowest level of azelaic acid.

Conclusions
The detection of urinary trans-4-hydroxy-L-proline after AKI could be treated as an early warning of chronic DN progression and might be linked to renal fibrosis. Urinary azelaic acid can be used to monitor renal function noninvasively in DM and DN patients. Our results identified markers of AKI on DM and the chronic progression of DN. In addition, the progression of DN was associated with AKI-like episodes occurring in DM.
Camel meat marketing and camel meat marketplace in the Algerian northern Sahara-case of the region of Souf-
Authors: Zakaria Brahimi , Abdelhakim Senoussi , Bernard Faye 
Published: May 2020

A field survey involving 62 camel butchers from Souf region the Algerian northern Sahara was implemented in order to establish a typology of camel butcher and collect data on camel meat marketing, the diversity in marketing practices and camel meat marketplace. The collected data allowed to identify 4 homogeneous groups of butchers well distinguished between them after cluster analysis. (specialized young camel butchers, non-specialized rural butchers, traditional non-specialized urban butchers, modern and old urban specialized butchers). The present study confirmed the predominance of beef meat compared to camel meat among consumers, camel meat consumption being less successful in its environment. In-depth studies on camel meat sector are mandatory to identify the bottlenecks invalidating the promotion of the camel meat consumption.
Impact of ultrasound processing on some milk-borne microorganisms and the components of camel milk
Authors: Dhahir Namariq , Feugang Jean , Witrick Katherine , Park Seongbin , AbuGhazaleh Amer 
Published: May 2020

Inactivation of pathogenic bacteria Escherichia coli O157: H7 and Salmonella Typhimurium in camel milk was investigated using ultrasound processing (900 W, 20 kHz, 100% power level). In addition, the effect of ultrasound treatment on raw camel milk components was studied to detect changes in fatty acid profile, lipid peroxides, protein fractions, and volatile compounds. Bacterial strains (106 CFU/ml) were added to pasteurized camel milk samples (70 ml) and transferred into a sterile aluminum container (30 mm x 120 mm, 100-ml total capacity) and then subjected to continuous ultrasound processing for 15 min in an ice water bath using a 13-mm diameter probe. The standard plate count (SPC) agar method and the in vivo imaging system (IVIS) were used to evaluate the viability of bioluminescence-transformed bacteria (E. coli O157: H7 and S. Typhimurium). The continuous ultrasound processing of camel milk resulted in significant (P<0.05) reductions in S. Typhimurium and E. coli O157: H7. Relative to unsonicated raw camel milk, the cis-9, trans-11 conjugated linoleic acid (CLA) and trans-10, cis-12 CLA contents were not affected (P>0.05) by the ultrasound processing. The TBAR values, a marker of lipid peroxidation, and milk protein fractions were also similar (P>0.05) between the sonicated and unsonicated raw camel milk. A total of 24 volatile compounds (VC) were identified including 8 aldehydes, 3 ketones, 5 acids, 5 esters, 2 aromatic hydrocarbonate, and 1 sulfo compound. Of these 24 VC, eleven VC increased (P<0.05) and seven decreased (P<0.05) after sonication. In conclusion, the results of this study showed that ultrasound processing of camel milk was efficient in inactivating subsets of milk-borne pathogens without detrimental effects on camel milk fatty acids, lipid peroxides, and protein fractions. However, there were some changes in milk VC which may affect the sensory quality of milk.
A Strategy for Polysulfides/Polyselenides Protection Based on Co9S8@SiO2/C Host in Na‐SeS2 Batteries
Authors: Yang Tingting , Qi Yuruo , Zhong Wei , Tao Mengli , Guo Bingshu , Wu Yuanke , Bao Shu‐Juan , Xu Maowen 
Published: May 2020

AbstractTo obtain unbroken sulfides with delicate morphology from metal–organic frameworks (MOFs), a method for in situ growth of SiO2 protective layers on the surface of MOFs is proposed. This strategy can be successfully expanded to a variety of MOFs (ZIF‐67, Cu‐MOF, ZIF‐8, and PBA). Importantly, room‐temperature Na‐SeS2 batteries with Co9S8@SiO2/C prepared from ZIF‐67 as cathode host are assembled. Due to the hollow structure that can relieve the volume expansion and the co‐adsorption of sodium polysulfides/sodium polyselenides by Co9S8@SiO2/C, the SeS2/Co9S8@SiO2/C cathode shows excellent rate performance and Coulombic efficiency. In addition, ex situ X‐ray diffraction and in situ Raman results show that S8 and Se8 are generated after the discharge of SeS2, and Se8 is preferentially oxidized during charging.
High Areal Capacity Dendrite‐Free Li Anode Enabled by Metal–Organic Framework‐Derived Nanorod Array Modified Carbon Cloth for Solid State Li Metal Batteries
Authors: Wang Tian‐Shi , Liu Xiaobin , Wang Yu , Fan Li‐Zhen 
Published: May 2020

AbstractLi metal is one of the most promising anode materials for high energy density batteries. However, uncontrollable Li dendrite growth and infinite volume change during the charge/discharge process lead to safety issues and capacity decay. Herein, a carbonized metal–organic framework (MOF) nanorod arrays modified carbon cloth (NRA‐CC) is developed for uniform Li plating/stripping. The carbonized MOF NRAs effectively convert the CC from lithiophobic to lithiophilic, decreasing the polarization and ensuring homogenous Li nucleation. The 3D interconnected hierarchal CC provides adequate Li nucleation sites for reducing the local current density to avoid Li dendrite growth, and broadens internal space for buffering the volume change during Li plating/stripping. These characteristics afford a stable cycling of the NRA‐CC electrode with ultrahigh Coulombic efficiencies of 96.7% after 1000 h cycling at 2 mA cm−2 and a prolonged lifespan of 200 h in the symmetrical cell under ultrahigh areal capacity (12 mAh cm−2) and current (12 mA cm−2). The solid‐state batteries assembled with the composite Li anode, high‐voltage cathode (LiNi0.5Co0.2Mn0.3O2), and composite solid‐state electrolyte also deliver excellent cyclic and rate performance at 25 °C. This work sheds fresh insights on the design principles of a dendrite‐free Li metal anode for safe solid‐state Li metal batteries.
Thermal Management Enables Bright and Stable Perovskite Light‐Emitting Diodes
Authors: Zhao Lianfeng , Roh Kwangdong , Kacmoli Sara , Al Kurdi Khaled , Jhulki Samik , Barlow Stephen , Marder Seth R. , Gmachl Claire , Rand Barry P. 
Published: May 2020

AbstractThe performance of lead‐halide perovskite light‐emitting diodes (LEDs) has increased rapidly in recent years. However, most reports feature devices operated at relatively small current densities (<500 mA cm−2) with moderate radiance (<400 W sr−1 m−2). Here, Joule heating and inefficient thermal dissipation are shown to be major obstacles toward high radiance and long lifetime. Several thermal management strategies are proposed in this work, such as doping charge‐transport layers, optimizing device geometry, and attaching heat spreaders and sinks. Combining these strategies, high‐performance perovskite LEDs are demonstrated with maximum radiance of 2555 W sr−1 m−2, peak external quantum efficiency (EQE) of 17%, considerably reduced EQE roll‐off (EQE > 10% to current densities as high as 2000 mA cm−2), and tenfold increase in operational lifetime (when driven at 100 mA cm−2). Furthermore, with proper thermal management, a maximum current density of 2.5 kA cm−2 and an EQE of ≈1% at 1 kA cm−2 are shown using electrical pulses, which represents an important milestone toward electrically driven perovskite lasers.
A Self‐Cleaning Heterostructured Membrane for Efficient Oil‐in‐Water Emulsion Separation with Stable Flux
Authors: Cai Yahui , Chen Dongyun , Li Najun , Xu Qingfeng , Li Hua , He Jinghui , Lu Jianmei 
Published: May 2020

AbstractLack of clean water is a major global challenge. Membrane separation technology is an ideal choice for the treatment of industrial, domestic sewage owing to its low energy consumption and cost. However, membranes are highly susceptible to contamination, particularly during wastewater treatment, which has limited their practical applications in this field. Similarly, the flux of the membrane decreases with prolonged use due to its reduced interlayer spacing. Preparation of membranes with anticontamination properties and stable flux is the key to addressing this problem. In this study, a 2D heterostructure membrane with visible‐light‐driven self‐cleaning performance is prepared via a self‐assembly process. Notably, the addition of palygorskite increases the interlayer spacing of the graphene and heterojunction structures, which increases the flux of the membrane and avoids a decrease of the interlayer spacing of the membrane under pressure. The presence of a heterojunction with visible light catalytic properties effectively avoids membrane fouling and avoids a sharp decrease of the permeation flux. Importantly, the prepared 2D membrane has excellent separation performance for oil–water emulsions with both high flux and efficiency. These features suggest great potential for the prepared 2D membrane in wastewater treatment applications.
Plasmonic Janus Microspheres Created from Pickering Emulsion Drops
Authors: Kim Jong Bin , Lee Su Yeon , Min Nam Gi , Lee Seung Yeol , Kim Shin‐Hyun 
Published: May 2020

AbstractMetal nanostructures have been created in a film format to develop unique plasmonic properties. Here, well‐defined metal nanostructures are designed on the surface of microspheres to provide plasmonic microgranules. As conventional techniques are inadequate for nanofabrication on spherical surfaces, photocurable emulsion drops with a regular array of silica particles are employed at the interface to create periodic nanostructures. The silica particles, originating from the dispersed phase, fully cover the interface by forming a non‐close‐packed hexagonal array after drop generation, and slowly protrude to the continuous phase during aging while their interparticle separation decreases. Therefore, hexagonal arrays of spherical dimples with controlled geometry and separation are created on the surface of microspheres by photocuring the drops and removing the particles. Directional deposition of either aluminum or gold results in a continuous film with a hexagonal array of holes on the outermost surface and isolated curved disks in dimples, which renders the hemisphere of microspheres plasmonically colored. The resonant wavelength is controlled by adjusting the aging time, metal thickness, and size of silica particles, providing various plasmonic colors. This granular format of the plasmonic Janus microspheres will open a new avenue of optical applications including active color pixels, optical barcodes, and microsensors.
Ultrabroadband Photodetectors up to 10.6 µm Based on 2D Fe3O4 Nanosheets
Authors: Yin Chujun , Gong Chuanhui , Chu Junwei , Wang Xudong , Yan Chaoyi , Qian Shifeng , Wang Yang , Rao Gaofeng , Wang Hongbo , Liu Yuqing , Wang Xianfu , Wang Jianlu , Hu Weida , Li Chaobo , Xiong Jie 
Published: May 2020

AbstractThe ultrabroadband spectrum detection from ultraviolet (UV) to long‐wavelength infrared (LWIR) is promising for diversified optoelectronic applications of imaging, sensing, and communication. However, the current LWIR‐detecting devices suffer from low photoresponsivity, high cost, and cryogenic environment. Herein, a high‐performance ultrabroadband photodetector is demonstrated with detecting range from UV to LWIR based on air‐stable nonlayered ultrathin Fe3O4 nanosheets synthesized via a space‐confined chemical vapor deposition (CVD) method. Ultrahigh photoresponsivity (R) of 561.2 A W−1, external quantum efficiency (EQE) of 6.6 × 103%, and detectivity (D*) of 7.42 × 108 Jones are achieved at the wavelength of 10.6 µm. The multimechanism synergistic effect of photoconductive effect and bolometric effect demonstrates the high sensitivity for light with any light intensities. The outstanding device performance and complementary mixing photoresponse mechanisms open up new potential applications of nonlayered 2D materials for future infrared optoelectronic devices.
Reconfigurable Large‐Scale Pattern Formation Driven by Topological Defect Separation in Liquid Crystals
Authors: Aya Satoshi , Salamon Peter , Eber Nandor , Buka Agnes , Araoka Fumito 
Published: May 2020

AbstractLarge‐scale patterning of topological defects is vital and challenging from both fundamental and technological points of view in anisotropic fluids. However, this is usually difficult because of their unfavorably high‐energy states. Here, a simple but general pathway for topology engineering is presented: processing topological defects and shape large‐scale patterns in materials with liquid crystalline nature. Dragging field is created through flowing materials at liquid–liquid crystal phase transition temperature or designing electric‐field driven temperature gradient. The dragging fields coupled to a dense colony of topological defects with random spatial distribution form nontrivial periodic ordered topological patterns that are energetically unfavorable compared to the uniform ground state, but are stable in the stationary state. Topological polymeric films based on the strategy are also fabricated. The dragging speed and surface interactions are found to be dominant factors in generating and stabilizing the patterns. This strategy endows fluids with regular and large‐scale topological patterns, paving a new way for the development of fluids and gels with spatially modulated topological nature.
Renewable Energy from Wildflowers—Perennial Wild Plant Mixtures as a Social‐Ecologically Sustainable Biomass Supply System
Authors: von Cossel Moritz 
Published: May 2020

AbstractA growing bioeconomy requires increasing amounts of biomass from residues, wastes, and industrial crops for bio‐based products and bioenergy. There is much discussion about how industrial crop cultivation could promote social–ecological outcomes such as environmental protection, biodiversity conservation, climate change adaptation, food security, greenhouse gas mitigation, and landscape appearance. In Germany, maize (Zea mays L.) is the main biogas substrate source, despite being associated with problems such as erosion, biodiversity losses, an increase in wild boar populations and lowered landscape diversity. The cultivation of perennial wild plant mixtures (WPM) addresses many of these problems. Despite being less developed than maize, WPM cultivation has received notable attention among scientists in Germany over the past decade. This is mainly because WPMs clearly outperform maize in social–ecological measures, despite their methane yield performance. This review summarizes and discusses the results of 12 years of research and practice with WPMs as a social‐ecologically more benign bioenergy cropping system.
Multistep Crystallization and Melting Pathways in the Free‐Energy Landscape of a Au–Si Eutectic Alloy
Authors: Kurtuldu Güven , Löffler Jörg F. 
Published: May 2020

AbstractCrystals do eventually melt if they are heated to their characteristic melting point. However, this is practically only the case for high‐temperature stable crystals, whereas low‐temperature metastable crystals generally transform, before melting, into a more stable solid during heating. Here, it is illustrated that low‐temperature crystals can, however, be melted via fast differential scanning calorimetry (FDSC), even in metallic systems where nucleation and growth kinetics are rapid. For a Au–Si eutectic alloy, various metastable and stable solid states, i.e., (Au–α), (Au–β), γ, and (Au–Si), which form under well‐controlled conditions and melt at high heating rates by preventing the metastable‐to‐stable solid phase transition, are isolated. It is demonstrated that Au81.4Si18.6 can fully melt at various temperatures, i.e., 294 °C, 312 °C, 352 °C, and 363 °C, with differing melting enthalpies ranging from 6.52 to 9.83 kJ mol−1. The melting and crystallization paths of the metastable solids are determined by constructing an energy−temperature diagram. This approach advances the general understanding of nucleation in metallic and other systems, and is expected to contribute to the detailed understanding of thermophysical phenomena that occur at spatially reduced dimensions and/or short time scales, for example in thin‐film deposition, nanomaterials production, or additive manufacturing.
Spatially and temporally disparate data in systems agriculture: Issues and prospective solutions
Authors: Kharel Tulsi P. , Ashworth Amanda J. , Owens Phillip R. , Buser Michael 
Published: May 2020

AbstractBig Data in agriculture is growing rapidly through advancements in metagenomics, precision agriculture, and on‐farm sensor technologies, as well as through increased capacity to collect, process, and store these data. Concurrent with 60% increases in food production demands by 2050 and the need for sustainable intensification, is the increased need for data synthesis across temporal and spatial scales. Therefore, in our data‐rich world, what is lacking is a data management system across spatial and temporal resolutions including workflows, interpretation methodology, and a delivery structure for identifying optimal systems for sustainable intensification or diversification. Consequently, the objective of this paper is to explore the current state of handling spatially and temporally disparate data and offer solutions for developing a platform for bridging component parts (encompassing multiple scales and disciplines) to analyze system functionality for greater resiliency, which may help manage risk. Two datasets were generated using bibliometrics (research articles from systematic literature reviews) evaluated trends and historical Big Data applications in agronomy. Results indicate research and industry progress is advancing towards web‐based real‐time output delivery systems using several well‐established Big Data handling platforms (e.g., Amazon Web Service, Google Cloud, Microsoft Azure), which are not yet widely used by or designed for agronomic researchers. Cloud‐based computing may provide opportunities to extrapolate agricultural research results across larger scales. Authors suggest training and educating agricultural practitioners on Big Data principles, database management, improved data visualization, as well as incentives for data sharing for optimizing Big Data in systems agriculture as these research innovations emerge.
Patient characteristics of suspected mast‐cell activation syndrome with sinonasal obstruction: a single institution experience
Authors: Kim Jee‐Hong , Xi Shijun , Ference Elisabeth H. , Ge Marshall , Liu Mona M. , Wrobel Bozena B. 
Published: May 2020

BackgroundMast‐cell activation syndrome (MCAS) is increasingly recognized. Sinonasal obstruction is common among these patients. There is a paucity of literature describing the characteristics of MCAS and treatment outcomes.MethodsRetrospective review of 192 patients with nasal congestion July 2017 to May 2019 among 3 providers (1 allergist, 2 rhinologists) was conducted. Suspected MCAS criteria were as follows: (1) at least 2 recurrent severe symptoms in addition to nasal congestion: flushing, pruritus, urticaria, angioedema, wheezing, throat swelling, headache, hypotension, diarrhea; (2) clinical response to medications that target mast cell mediators. Quality of life (QOL) outcomes were quantified using the 22‐item Sino‐Nasal Outcome Test (SNOT‐22).ResultsThirty‐two patients with nasal congestion were suspected of MCAS. The median age was 47 years; 24 of 32 were female; 13 of 32 had prior history of sinonasal surgery and 11 of 32 allergen immunotherapy. Out of 32, 19 had history of asthma, 10 drug allergy, 11 food allergy, and 10 anaphylaxis. The median number of medications targeting mast cell activation was 4 (range, 2‐7). Eleven patients were offered surgery by a rhinologist after adequate medical management. Three of 32 patients showed elevation of serum tryptase. Fourteen completed pretreatment and posttreatment SNOT‐22 (4/14 surgery, 10/14 medical management). Pretreatment score was 59.8 ± 6.2 (mean ± standard error [SEM]) and posttreatment score was 42.8 ± 6.7; the difference was statistically and clinically significant (p = 0.0015). Both groups showed a mean 17‐point reduction.ConclusionA multidisciplinary approach to the treatment of sinonasal symptoms using both escalation of medical therapy and surgical approaches may improve QOL of patients with suspected MCAS. Consensus criteria for MCAS, which includes elevation in tryptase over baseline during an episode, may exclude the full spectrum of individuals with MCAS from potentially beneficial treatment.
Bildung Stabiler All‐Silicium Varianten von 1,3‐Cyclobutandiyl im Gleichgewicht
Authors: Yildiz Cem B. , Leszczyńska Kinga I. , González‐Gallardo Sandra , Zimmer Michael , Azizoglu Akin , Biskup Till , Kay Christopher W. M. , Huch Volker , Rzepa Henry S. , Scheschkewitz David 
Published: May 2020

AbstractHauptgruppenanaloga von 1,3‐Cyclobutandiylen faszinieren mit ihrer einzigartigen Reaktivität und ihren elektronischen Eigenschaften. Bisher sind allerdings nur heteronukleare Vertreter isoliert worden. Wir berichten hier über die Isolierung und Charakterisierung von All‐Silicium‐1,3‐Cyclobutandiylen als stabile Singulettspezies mit geschlossenschaliger Konfiguration aus den reversiblen Reaktionen von Cyclotrisilen c‐Si3Tip4 (Tip=2,4,6‐Triisopropylphenyl) mit den N‐heterocyclischen Silylenen c‐[(CR2CH2)(NtBu)2]Si: (R=H oder Methyl) mit gesättigten Grundgerüsten. Bei erhöhten Temperaturen werden aus diesen Gleichgewichtsmischungen Tetrasilacyclobutene erhalten. Die analoge Reaktion mit dem ungesättigten N‐heterocyclischen Silylen c‐(CH)2(NtBu)2Si: verläuft direkt zum entsprechenden Tetrasilacyclobuten ohne Nachweis des angenommenen 1,3‐Cyclobutandiyl‐Zwischenprodukts.