bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-tumor necrosis factor therapy in patients with inflammatory bowel disease; comorbidity, not patient age, is a predictor of severe adverse events
Authors: Asscher Vera E. R. , van der Vliet Quirine , van der Aalst Karen , van der Aalst Anniek , Brand Eelco C. , van der Meulen-de Jong Andrea E. , Oldenburg Bas , Pierik Marieke J. , van Tuyl Bas , Mahmmod Nofel , Maljaars P. W. Jeroen , Fidder Herma H. ,   On behalf of the Dutch ICC
Published: August 2020

Abstract
Purpose
To assess safety and effectiveness of anti-tumor necrosis factor (anti-TNF) therapy in IBD patients ≥ 60 years.

Methods
Ninety IBD patients ≥ 60 years at initiation of anti-TNF therapy, 145 IBD patients ≥ 60 years without anti-TNF therapy and 257 IBD patients < 60 years at initiation of anti-TNF therapy were retrospectively included in this multicentre study. Primary outcome was the occurrence of severe adverse events (SAEs), serious infections and malignancies. Secondary outcome was effectiveness of therapy. Cox regression analyses were used to assess differences in safety and effectiveness. In safety analyses, first older patients with and without anti-TNF therapy and then older and younger patients with anti-TNF therapy were assessed.

Results
In older IBD patients, the use of anti-TNF therapy was associated with serious infections (aHR 3.920, 95% CI 1.185–12.973, p = .025). In anti-TNF-exposed patients, cardiovascular disease associated with serious infections (aHR 3.279, 95% CI 1.098–9.790, p = .033) and the presence of multiple comorbidities (aHR 9.138 (1.248–66.935), p = .029) with malignancies, while patient age did not associate with safety outcomes. Effectiveness of therapy was not affected by age or comorbidity.

Conclusion
Older patients receiving anti-TNF therapy have a higher risk of serious infections compared with older IBD patients without anti-TNF therapy, but not compared with younger patients receiving anti-TNF therapy. However, in anti-TNF-exposed patients, comorbidity was found to be an indicator with regards to SAEs. Effectiveness was comparable between older and younger patients.
Hedonicity in functional motor disorders: a chemosensory study assessing taste
Authors: Cecchini Maria Paola , Tamburin Stefano , Zanini Alice , Boschi Federico , Demartini Benedetta , Goeta Diana , Dallocchio Carlo , Marotta Angela , Fiorio Mirta , Tinazzi Michele 
Published: August 2020

AbstractThe aim of this study was to explore hedonicity to basic tastes in patients with functional motor disorders (FMDs) that are often associated with impairment in emotional processing. We recruited 20 FMD patients and 24 healthy subjects, matched for age and sex. Subjects were asked to rate the hedonic sensation (i.e., pleasant, neutral, and unpleasant) on a − 10 to +10 scale to the four basic tastes (sweet, sour, salty, and bitter) at different concentrations, and neutral stimuli (i.e., no taste stimulation) by means of the Taste Strips Test. Anxiety, depression, and alexithymia were assessed. FMD patients rated the highest concentration of sweet taste (6.7 ± 2.6) as significantly more pleasant than controls (4.7 ± 2.5, p = 0.03), and the neutral stimuli significantly more unpleasant (patients: − 0.7 ± 0.4, controls: 0.1 ± 0.4, p = 0.013). Hedonic ratings were not correlated to anxiety, depression, or alexithymia scores. Hedonic response to taste is altered in FMD patients. This preliminary finding might result from abnormal interaction between sensory processing and emotional valence.
Advanced materials and technologies for supercapacitors used in energy conversion and storage: a review
Authors: Abdel Maksoud M. I. A. , Fahim Ramy Amer , Shalan Ahmed Esmail , Abd Elkodous M. , Olojede S. O. , Osman Ahmed I. , Farrell Charlie , Al-Muhtaseb Ala’a H. , Awed A. S. , Ashour A. H. , Rooney David W. 
Published: August 2020

AbstractSupercapacitors are increasingly used for energy conversion and storage systems in sustainable nanotechnologies. Graphite is a conventional electrode utilized in Li-ion-based batteries, yet its specific capacitance of 372 mA h g−1 is not adequate for supercapacitor applications. Interest in supercapacitors is due to their high-energy capacity, storage for a shorter period and longer lifetime. This review compares the following materials used to fabricate supercapacitors: spinel ferrites, e.g., MFe2O4, MMoO4 and MCo2O4 where M denotes a transition metal ion; perovskite oxides; transition metals sulfides; carbon materials; and conducting polymers. The application window of perovskite can be controlled by cations in sublattice sites. Cations increase the specific capacitance because cations possess large orbital valence electrons which grow the oxygen vacancies. Electrodes made of transition metal sulfides, e.g., ZnCo2S4, display a high specific capacitance of 1269 F g−1, which is four times higher than those of transition metals oxides, e.g., Zn–Co ferrite, of 296 F g−1. This is explained by the low charge-transfer resistance and the high ion diffusion rate of transition metals sulfides. Composites made of magnetic oxides or transition metal sulfides with conducting polymers or carbon materials have the highest capacitance activity and cyclic stability. This is attributed to oxygen and sulfur active sites which foster electrolyte penetration during cycling, and, in turn, create new active sites.
How Robust is Robust Control in Discrete Time?
Authors: Tucci Marco P. 
Published: August 2020

AbstractBy applying robust control, the decision maker wants to make good decisions when his model is only a good approximation of the true one. Such decisions are said to be robust to model misspecification. In this paper it is shown that, in many situations relevant in economics, a decision maker applying robust control implicitly assumes that today’s worst-case adverse shock is serially uncorrelated with tomorrow’s worst-case adverse shock. Then, further investigation is needed to see how strong is the ‘immunization against uncertainty’ provided by these popular frameworks.
Smart water consumption measurement system for houses using IoT and cloud computing
Authors: Fuentes Henry , Mauricio David 
Published: August 2020

AbstractPresently, in several parts of the world, water consumption is not measured or visualized in real time, in addition, water leaks are not detected in time and with high precision, generating unnecessary waste of water. That is why this article presents the implementation of a smart water measurement consumption system under an architecture design, with high decoupling and integration of various technologies, which allows real-time visualizing the consumptions, in addition, a leak detection algorithm is proposed based on rules, historical context, and user location that manages to cover 10 possible water consumption scenarios between normal and anomalous consumption. The system allows data to be collected by a smart meter, which is preprocessed by a local server (Gateway) and sent to the Cloud from time to time to be analyzed by the leak detection algorithm and, simultaneously, be viewed on a web interface. The results show that the algorithm has 100% Accuracy, Recall, Precision, and F1 score to detect leaks, far better than other procedures, and a margin of error of 4.63% recorded by the amount of water consumed.
Absolute points of correlations of $$PG(3,q^n)$$
Authors: Donati Giorgio , Durante Nicola 
Published: August 2020

AbstractThe sets of the absolute points of (possibly degenerate) polarities of a projective space are well known. The sets of the absolute points of (possibly degenerate) correlations, different from polarities, of $${{\mathrm{PG}}}(2,q^n)$$

PG
(
2
,

q
n

)

, have been completely determined by B.C. Kestenband in 11 papers from 1990 to 2014, for non-degenerate correlations and by D’haeseleer and Durante (Electron J Combin 27(2):2–32, 2020) for degenerate correlations. In this paper, we completely determine the sets of the absolute points of degenerate correlations, different from degenerate polarities, of a projective space $${{\mathrm{PG}}}(3,q^n)$$

PG
(
3
,

q
n

)

. As an application we show that, for q even, some of these sets are related to the Segre’s $$(2^h+1)$$

(

2
h

+
1
)

-arc of $${{\mathrm{PG}}}(3,2^n)$$

PG
(
3
,

2
n

)

and to the Lüneburg spread of $${{\mathrm{PG}}}(3,2^{2h+1})$$

PG
(
3
,

2

2
h
+
1

)

.
Adsorption properties of iodine on fused silica surfaces when evaporated from tellurium in various atmospheres
Authors: Karlsson Erik , Neuhausen Jörg , Eichler Robert , Vögele Alexander , Türler Andreas 
Published: August 2020

AbstractThe evaporation of iodine containing species from tellurium has been investigated together with their adsorption behavior on a fused silica surface. In inert gas, the formation of two species was observed with adsorption enthalpies of around − 90 to − 100 and − 110 to − 120 kJ/mol, respectively. For reducing environments, a single species identified as monatomic iodine was observed with an adsorption enthalpy around − 95 kJ/mol. In oxidizing conditions, species with low adsorption enthalpies ranging from − 65 to − 80 kJ/mol were observed. Presumably, these are iodine oxides as well as oxo-acids of iodine (HIOx). The results of the thermochromatography experiments performed here prove the usefulness of the employed production method for carrier-free iodine isotopes and enhance the understanding of the evaporation and deposition behavior of iodine under various chemical conditions.
A highly flexible laboratory setup to demonstrate granular flow characteristics
Authors: Heinze Thomas 
Published: August 2020

AbstractDynamics of snow avalanches or landslides can be described by rapid granular flow. Experimental investigations of granular flow at laboratory scale are often required to analyze flow behaviour and to develop adequate mathematical and numerical models. Most investigations use image-based analysis, and additional sensors such as pressure gauges are not always possible. Testing various scenarios and parameter variations such as different obstacle shapes and positions as well as basal topography and friction usually requires either the construction of a new laboratory setups for each test or a cumbersome reconstruction. In this work, a highly flexible and modular laboratory setup is presented based on LEGO bricks. The flexibility of the model is demonstrated, and possible extensions for future laboratory tests are outlined. The setup is able to reproduce published laboratory experiments addressing current scientific research topics, such as overflow of a rigid reflector, flow on a bumpy surface and against a rigid wall using standard image-based analysis. This makes the setup applicable for quick scenario testing, e.g. for hypothesis testing or for low-cost testing prior to large-scale experiments, and it can contribute to the validation of external results and to benchmarks of numerical models. Small-scale laboratory setups are also very useful for demonstration purposes such as education and public outreach, both crucial in the context of natural hazards. The presented setup enables variation of parameters such as of slope length, channel width, height and shape, inclination, bed friction, obstacle position and shape, as well as density, composition, amount and grain size of flowing mass. Observable quantities are flow type, flow height, flow path and flow velocity, as well as runout distance, size and shape of the deposited material. Additional sensors allow further quantitative assessments, such as local pressure values.
Explaining the political use of evaluation in international organizations
Authors: Eckhard Steffen , Jankauskas Vytautas 
Published: August 2020

AbstractDespite a growing literature on the politics of evaluation in international organizations (IOs) and beyond, little is known about whether political or administrative stakeholders indeed realize ex-ante political interests through evaluations. This is, however, especially important considering the booming business of evaluation and the proliferation of institutional assessments both in domestic and international politics. We argue that formally independent IO evaluation units informally orientate towards either member states or the IO administration, depending on who controls the unit’s budget, staff, and agenda resources. This should enable either actor to also use evaluation results along pre-defined strategic interests. Interview data gathered among evaluators, secretariat officials, and member state representatives of six IOs support the expected pattern, highlighting striking differences in the orientation of evaluation staff and evaluation use. Findings challenge the technocratic, apolitical image of evaluation, offering practical and theoretical implications for future research.
Investigating temporal and spatial correlates of the sharp decline of an urban exploiter bird in a large European city
Authors: Mohring Bertille , Henry Pierre-Yves , Jiguet Frédéric , Malher Frédéric , Angelier Frédéric 
Published: August 2020

AbstractIncreasing urbanisation and human pressure on lands have huge impacts on biodiversity. Some species, known as “urban exploiters”, manage to expand in urban landscapes, relying on human resources. The House Sparrow (Passer domesticus) is the perfect example of a human-commensal species. Surprisingly, this urban exploiter has been declining all over Europe over the past decades. The proximate causes of this decline remain poorly understood. We particularly lack understanding about urban habitat characteristics that are particularly unfavourable for House Sparrows. In the present study, we analysed fine-scale habitat characteristics of House Sparrow population sizes and trends using a fifteen-year House Sparrow census (2003–2017) covering the urban diversity of Paris (nearly 200 census sites), one of the densest European cities. We documented for the first time the dramatic decline (−89%) of the species in Paris over the study period. The temporal decline over the whole city correlates with the concomitant increase in the number of breeding Sparrowhawks. We could not detect statistical influences of annual variations in weather conditions and pollution. The decline of House Sparrows is spatially heterogeneous. Indeed, site-scale analyses revealed sharpest declines at sites that initially hosted the largest numbers of sparrows, which are areas with a relatively high proportion of green spaces and new buildings. Further experimental studies are now needed to disentangle the exact impact of specific characteristics of the urban environment on House Sparrow populations.
Spin excitations and spin wave gap in the ferromagnetic Weyl semimetal Co3Sn2S2
Authors: Liu Chang , Shen JianLei , Gao JiaCheng , Yi ChangJiang , Liu Di , Xie Tao , Yang Lin , Danilkin Sergey , Deng GuoChu , Wang WenHong , Li ShiLiang , Shi YouGuo , Weng HongMing , Liu EnKe , Luo HuiQian 
Published: August 2020

AbstractWe report a comprehensive neutron scattering study on the spin excitations in the magnetic Weyl semimetal Co3Sn2S2 with a quasi-two-dimensional structure. Both in-plane and out-of-plane dispersions of the spin waves were revealed in the ferromagnetic state. Similarly, dispersive but damped spin excitations were found in the paramagnetic state. The effective exchange interactions were estimated using a semi-classical Heisenberg model to consistently reproduce the experimental TC and spin stiffness. However, a full spin wave gap below Eg = 2.3 meV was observed at T = 4 K. This value was considerably larger than the estimated magnetic anisotropy energy (~0.6 meV), and its temperature dependence indicated a significant contribution from the Weyl fermions. These results suggest that Co3Sn2S2 is a three-dimensional correlated system with a large spin stiffness, and the low-energy spin dynamics can interplay with the topological electron states.
Probabilistic information fusion to model the pose-dependent dynamics of milling robots
Authors: Busch Maximilian , Schnoes Florian , Semm Thomas , Zaeh Michael F. , Obst Birgit , Hartmann Dirk 
Published: August 2020

AbstractConventional industrial robots are increasingly used for milling applications of large workpieces due to their workspace and their low investment costs in comparison to conventional machine tools. However, static deflections and dynamic instabilities during the milling process limit the efficiency and productivity of such robot-based milling systems. Since the pose-dependent dynamic properties of the industrial robot structures are notoriously difficult to model analytically, machine learning methods are recently gaining more and more popularity to derive system models from experimental data. In this publication, a modeling concept based on a modern information fusion scheme, fusing simulation and experimental data, is proposed. This approach provides a precise model of the robot’s pose-dependent structural dynamics and is validated for a one-dimensional variation of the robot pose. The results of two information fusion algorithms are compared with a conventional, data-driven approach and indicate a superior model accuracy regarding interpolation and extrapolation of the pose-dependent dynamics. The proposed approach enables decreasing the necessary amount of experimental data needed to assess the vibrational properties of the robot for a desired pose. Additionally, the concept is able to predict the robot dynamics at poses where experimental data is very costly to gather.
A Literature Systematic Review with Meta-Analysis of Symptoms Prevalence in Covid-19: the Relevance of Olfactory Symptoms in Infection Not Requiring Hospitalization
Authors: Giorli A. , Ferretti F. , Biagini C. , Salerni L. , Bindi I. , Dasgupta S. , Pozza A. , Gualtieri G. , Gusinu R. , Coluccia A. , Mandalà Marco 
Published: August 2020

Abstract
Purpose of review
To investigate the association between the olfactory dysfunction and the more typical symptoms (fever, cough, dyspnoea) within the Sars-CoV-2 infection (COVID-19) in hospitalized and non-hospitalized patients.

Recent findings
PubMed, Scopus and Web of Science databases were reviewed from May 5, 2020, to June 1, 2020. Inclusion criteria included English, French, German, Spanish or Italian language studies containing original data related to COVID19, anosmia, fever, cough, and dyspnoea, in both hospital and non-hospital settings. Two investigators independently reviewed all manuscripts and performed quality assessment and quantitative meta-analysis using validated tools. A third author arbitrated full-text disagreements. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), 11 of 135 studies fulfilled eligibility. Anosmia was estimated less prevalent than fever and cough (respectively rate difference = − 0.316, 95% CI: − 0.574 to − 0.058, Z = − 2.404, p < 0.016, k = 11 and rate difference = − 0.249, 95% CI: − 0.402 to − 0.096, Z = − 3.185, p < 0.001, k = 11); the analysis between anosmia and dyspnoea was not significant (rate difference = − 0.008, 95% CI: − 0.166 to 0.150, Z = − 0.099, p < 0.921, k = 8). The typical symptoms were significantly more frequent than anosmia in hospitalized more critical patients than in non-hospitalized ones (respectively [Q(1) = 50.638 p < 0.000, Q(1) = 52.520 p < 0.000, Q(1) = 100.734 p < 0.000).

Summary
Patient with new onset olfactory dysfunction should be investigated for COVID-19. Anosmia is more frequent in non-hospitalized COVID-19 patients than in hospitalized ones.
Experimental study on the working performance of different milling tools for multistage fracturing ball seats
Authors: Che Jia-Qi , Wang Han-Xiang , Zhang Yan-Wen , Du Ming-Chao , Ma Shao-Hua 
Published: August 2020

AbstractTo achieve the secondary production in multistage fracturing wells of tight oil, milling tools are usually used to remove the multistage fracturing ball seats to achieve production with a large diameter in later. In this paper, first of all, the working mechanism of milling tools for multistage fracturing ball seats was studied and a mechanical analysis model of single abrasive grain was established. Then, an experimental system for milling tools was developed, and the experimental tests of the flat, the blade, and the slope milling tool were conducted in order. Besides, the morphology of chips and the surface morphology of the workpiece after the experiment were analyzed. Also, the working performance of milling tools was evaluated from the perspectives of working safety, working efficiency, and wear resistance of the milling tool. The results show that the torque of the milling tool increases nonlinearly with the increase in the cutting depth of the abrasive grain and increases linearly with the increase in the cutting width. Also, the chips are irregular particles and the size is mainly from 10 to 50 μm. So, the chips should be pumped up with a small pump pressure and a large displacement. Besides this, the cutting depths of the abrasive grains are from 216.20 to 635.47 μm and the bottom surface of the milling tool should be eccentric to avoid the zero point of cutting speed. Furthermore, the torque of the slope milling tool is 23.8% larger than that of the flat milling tool, which is also 30.4% smaller than that of the blade milling tool. Compared with the flat milling tool, the working efficiency of the blade milling tool improves by 79.9% and the slope milling tool improves by 111.1%. Also, the wear resistance of the blade milling tool decreases by 102.7%, while the slope milling tool declines by 32.6% when compared with the flat milling tool. Therefore, the slope milling tool has the characteristics of moderate torque, stable working conditions, the highest working efficiency, and fine wear resistance, which is preferably used to mill multistage fracturing ball seats. This study provides a theoretical basis and guidance for milling multistage fracturing ball seats on-site and realizing production with a large diameter in later stages of multistage fracturing wells.
Rapid aerobic granulation using biochar for the treatment of petroleum refinery wastewater
Authors: Wang Xin , Ming Jie , Chen Chun-Mao , Yoza Brandon A. , Li Qian-Wei , Liang Jia-Hao , Gadd Geoffrey Michael , Wang Qing-Hong 
Published: August 2020

Abstract
Aerobic granular sludge technology has great potential for the treatment of petroleum refinery wastewater. However, strategies to shorten the granulation time and improvement the stability still need to be developed. In this work, biochar was prepared from waste petroleum activated sludge (biochar-WPS) and used in a sequencing batch reactor for the treatment of petroleum refinery wastewater. Biochar-WPS presented the surface area of 229.77 m2/g, pore volume of 0.28 cm3/g, H/C and O/C atomic ratios of 0.42 and 0.21, respectively. The porous structure and a high degree of hydrophilicity were found to facilitate microbial colonization and adhesion as well as particle aggregation. Application of biochar-WPS resulted in the formation of more substantial and stable aerobic granules (~ 66% of granules > 0.46 mm diameter) 15 days earlier compared with the control. The addition of biochar-WPS enhanced the average removal efficiency of chemical organic demand (~ 3%), oil (~ 4%) and total nitrogen (~ 10%) over the control. Increased microbial richness and diversity were observed within the formed granules and had an increased (~ 4%) proportion of denitrifying bacteria. These results indicate that an aerobic granulation mechanism using biochar-WPS is a feasible option for the treatment of petroleum refinery wastewater.