bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pluriversos indígenas y ejercicios de resistencia
Authors: Garzón Mantilla Anamaría , Fabbri Juan 
Published: December 2020

Esta edición de post(s) nace de la escucha atenta de los movimientos de protesta que ocurrieron en las calles de distintas ciudades Latinoamericanas en el 2019. Nace de la observación de los gestos de diversas instituciones artísticas y académicas que empiezan a cuestionar sus propios cánones. Nace también para acoger unas potentes voces indígenas que, desde la academia, los activismos y la praxis artística, demandan pensar y repensar distintos campos de pensamiento, metodologías de investigación y formas de relación con lxs otrxs y con la historia.
La convocatoria, escrita por Juan Fabbri, proponía una provocación para pensar en prácticas artísticas contemporáneas y su relación con las naciones indígenas, originarias y campesinas, pensando en qué papel juega el arte en un escenario de cambios, reivindicaciones y luchas sociales. Pero los artículos que se presentan en esta edición van más allá de eso. El tema se desbordó y quienes acudieron al llamado de la revista la ocuparon y cambiaron la agenda. Desde el equipo editorial de post(s), dirigido por Anamaría Garzón, acogemos esa ocupación con entusiasmo y los ensayos que se presentan hablan de practicas artísticas y curatoriales, sí, pero también hablan de conflictos de raza, de disidencias sexo genéricas, de las vidas marcadas por las migraciones, del bilingüismo, de prácticas de la cultura popular, de resistencias frente al extractivismo y del lugar de lxs cuerpos mestizxs, campurías, criollxs y racializadxs en estas conversaciones
The City of Man and the critique of fascism: The perspective of Hermann Broch
Authors: Lichański Jakub Z. 
Published: December 2020

The City of Man initiative, with a conscious reference to Saint Augustine’s De civitate Dei, wanted to build a system after the First World War that would ensure free and unfettered human development. This initiative was undertaken by emigrants from Europe and eminent American intellectuals: they all hoped that a realized democracy in the classical Greek sense of the word would not only give us peace, but also open a perspective that, among other things, would eliminate socialism in its fascist and Bolshevik variants.
Why do I open, however, an article devoted to this somewhat forgotten initiative with remarks on the subject of Hermann Broch, who, though he played an important role in the work of this group, was simply “one of many” (exactly one of the seventeen members of the group)? This is due to the fact that his voice was weighty. I also follow Paul Michael Lützeler’s suggestions; it must be remembered that the issues raised in the manifesto of the aforementioned group were taken up by the writer and philosopher, from the beginning of his activity, i.e. from his debut in 1931. It is worth looking at how the artist solved the same problems, which he then “tried” to describe and analyze as a philosopher and theoretician of economics.
Dos efectos de la Covid-19 en Colombia: profundización de la desigualdad y retorno al hiperpresidencialismo
Authors: Barrera Varela Pedro Javier 
Published: December 2020

El presente artículo tiene como objeto analizar desde una postura crítica, con soporte teórico y fáctico, los cambios que ha sufrido el ordenamiento jurídico colombiano a partir de la declaratoria del Estado de excepción. La investigación propone como tesis que el excesivo incremento normativo en cabeza dellegislador excepcional arrojó dos nefastas consecuencias para la sociedad colombiana: profundización de la desigualdad y retorno al hiperpresidencialismo. Así, para sustentar la tesis anteriormente mencionada, se desarrollaron tres argumentos. Primero, se plantea que en el contexto colombiano persisten dos constantes: desigualdad y exclusión. Para defender esta premisa fueron analizadas algunas sentencias proferidas por las altas cortes y datos estadísticos que la confirman. También, se presenta la radiografía del derecho a la salud, la cual pone en evidencia que el sector padece la enfermedad de la corrupción sistémica.Segundo, se analiza el diseño constitucional colombiano para concluir que, en el escenario actual, los distintos poderes han sido cooptados por el presidente de la república. Tercero, se realiza una valoración crítica de los decretos legislativos expedidos en el marco del Estado de excepción, y se concluye que, por lo menos, 34 decretos eran innecesarios, inconvenientes o inconstitucionales. Lo más crítico del último argumento fue evidenciar el débil papel de la Corte Constitucional en su ejercicio de control automático de constitucionalidad.
Del Ulises desatado al Ulises extraviado: la crisis sanitaria en el contexto de la crisis constitucional chilena
Authors: Morales Antonio 
Published: December 2020

El presente artículo ofrece un análisis de la reacción institucional a la pandemia de COVID-19 en el caso chileno, centrándose en el rol de los poderes ejecutivo y legislativo, así como en el impacto que el contexto actual ha tenido en las dinámicas de interacción entre ambos poderes del Estado. Las formas de control de la crisis sanitaria encuentran un antecedente directo en las formas de control implementadas para reaccionar a la crisis social iniciada en octubre de 2019. Dado lo anterior, el escrito detecta las continuidades e interrupciones identificables en las respuestas a ambas crisis, analizando qué representa la trayectoria institucional del último año para el presidencialismo chileno en tanto cultura política y forma jurídica degestión del poder público. La evaluación del caso chileno se realiza a partir de la tensión entre dos modelos de análisis para estudiar la vigencia actual del principio de separación de poderes: por un lado, la propuestadel ejecutivo desatado, desarrollada por Posner y Vermeule; por otro lado, el modelo deliberativo expuesto por Ginsburg y Versteeg. El artículo concluye brindando una perspectiva propia a modo de diagnóstico dela situación actual, analizando elementos de diseño institucional que resultan relevantes para el proceso constitucional actualmente en curso en el país.
Emergencia pública, presidencialismo y Estado de Derecho en Argentina en el contexto del COVID-19
Authors: Altavilla Cristian 
Published: December 2020

La pandemia generada por el COVID-19 activó los resortes institucionales previstos por la Constitución argentina para enfrentar emergencias públicas. Sin embargo, la magnitud e impacto de la situación generada por la pandemia del COVID-19 superó y excedió cualquier previsión legal y/o constitucional.La emergencia sanitaria puso de resalto una serie de problemas tanto sociales, políticos y económicos, como del propio diseño institucional del sistema constitucional argentino. El objetivo del presente trabajoes analizar el rol de los poderes del Estado Argentino en esta situación extraordinaria de emergencia pública sanitaria y su desempeño en el mismo, a través de una mirada crítica sobre su actuación, para examinar si seha desarrollado en el marco de legalidad establecido por el régimen constitucional, o si bien ha estado al margen de dicha legalidad. La República Argentina comparte con sus hermanas naciones latinoamericanas el fenómeno denominado “hiperpresidencialismo”, manifestado en la gran cantidad de atribuciones (de hecho y de derecho) que ejerce el presidente de la nación, como encargado del poder ejecutivo, situación que termina por generar un peligroso desequilibrio de poderes que atenta contra el sistema democrático y republicano. La pandemia, en este sentido, no hizo más que poner de resalto esta anomalía del sistemaconstitucional.
EDUCAÇÃO SEXUAL EMANCIPATÓRIA E O PENSAMENTO CRÍTICO: REFLEXÕES SOBRE SABERES E FAZERES DO GRUPO EDUSEX
Authors: Melo Sonia Maria Martins de , Pacheco Raquel Da Veiga , Freitas Marcia De 
Published: December 2020

Reflexões sobre parte da caminhada de 30 anos do Grupo EDUSEX Formação de Educadores e Educação Sexual na Universidade do Estado de Santa Catarina, na sensibilização dos envolvidos em processos educativos formais e não formais, subsidiando o resgate da sua capacidade de pensamento crítico sobre o contexto, em interfaces com educação sexual. Sintetiza o significado de educação sexual e educação sexual emancipatória, via materialismo sócio-histórico-dialético como base de possibilidades concretas da construção de projetos intencionais em educação sexual emancipatória, com dois exemplos: os resultados relacionados ao mapeamento do estado da produção do conhecimento sobre a categoria educação sexual em PPGE no Brasil e os resultados de estágio doutoral, na Universidade de Aveiro (PT), em programas de rádios comunitárias com interfaces entre educação sexual emancipatória e pensamento crítico.
Maldonado
Authors: Brito Vinícius 
Published: December 2020

O corpo de Salvador Maldonado ficou desaparecido por dois meses, depois de o jovem de 28 anos ter participado de um protesto em defesa da comunidade mapuche Pu Lof em Resistência, na comuna rural de Cushamen, a 1º de agosto de 2017. No dia 17 de outubro daquele ano, porém, o ativista foi encontrado sem vida no rio Chubut, próximo ao local onde a polícia nacional (“gendarmería”) havia repreendido, de forma truculenta, o ato mapuche, em agosto. A partir daí, o debate público, as organizações sociais e a família de Maldonado cobraram investigação do governo nesse caso, que mostra luzes/sombras do poder, frente aos direitos humanos (BARBUTO, 2017). Sustentada por peritos, a versão oficial para a morte do ativista é de afogamento, negando, portanto, a repressão violenta dos policiais e a responsabilidade do Estado.
O desaparecimento e a morte de Maldonado ressoaram em diversas mobilizações sociais no segundo semestre de 2017 na Argentina, viabilizando, entre outros, o ativismo artístico (CAPASSO, BUGNONE, 2019). Ao mesmo tempo, a “inscrição” do militante em fotografias/cartazes de movimentos sociais no espaço urbano marca, segundo Catela (2019), o cenário violento da relação entre Estado e povos originários, como os mapuches, e, também, remete aos regimes autoritários, na história recente da América Latina e, em especial, a da Argentina.
Há três anos da desaparição/morte de Maldonado, inicio esta série de foto-colagens com a Imagem 1, sobre cartazes afixados nas paredes de Buenos Aires, capital argentina. Nela, vemos fragmentos de dois anúncios, parcialmente rasgados, nos quais lemos “aparición con vida ya de Santiago Maldonado” e “el gobierno y el Estado son responsables”. Em ambos, reproduz-se, em desdobramento, uma fotografia de um cartaz de manifestação pela vida do mapuche (no canto superior, à direita) e uma imagem contrastada dele (no canto inferior, à esquerda). A esta foto-colagem chamo, a princípio, de “abstrata”, porque mostra esse funcionamento de desdobramento do cartaz, que remete a outros cartazes/dizeres, dentro de certa memória do ativismo latino-americano.
PENDEKATAN INSTRUKSIONAL PADA PERMAINAN ‘FAST FOR WORD READING SERIES’ UNTUK PERKEMBANGAN KETERAMPILAN MEMBACA BAHASA INGGRIS ANAK DWIBAHASA
Authors: Zakiyah Fitriyatuz 
Published: December 2020

Abstrak Aplikasi Permainan ‘Fast for Word Reading Series’ menawarkan proses pengajaran membaca bahasa Inggris yang efektif hanya dalam kurun waktu kurang dari satu tahun. Aplikasi ini menggunakan pendekatan Effective Reading yang telah dipaparkan oleh National Learning Corporation. Tujuan dari penelitian ini adalah untuk menganalisis peran pendekatan instruksional Effective Reading pada sebuah game untuk meningkatkan kemampuan membaca bahasa Inggris anak. Penelitian ini merupakan deskriptif kualitatif untuk menjelaskan secara rinci bagaimana metode yang digunakan oleh permainan tersebut dinilai efektif dalam meningkatkan keterampilan membaca anak. Objek pada penelitian ini adalah aplikasi Fast for Word Reading Series. Hasil menunjukkan bahwa lima pendekatan dari effective Reading telah diterapkan dalam permainan Fast for Word Reading Series. Kelima tahap itu, telah membagi permainan ini menjadi enam seri. Sehingga anak mampu meningkatkan keterampilan dan pemahaman membaca bahasa Inggris dengan baik. Selain itu, melalui pendekatan yang efektif dan pembelajaran yang dimulai dari dasar yaitu kesadaran fonemik hingga mampu mebaca dan memahami suatu teks yang mereka baca.
POSITIVE POLITENESS STRATEGIES USED BY DAVID MUIR AND DONALD TRUMP ON “ABC NEWS” AND IN “CHARLIE ROSE SHOW”
Authors: Marpudianto Kharis 
Published: December 2020

Abstract This research examines Donald Trump and David Muir’s Utterances on ABC News and in Charlie Rose Show. The researcher also focuses positive politeness used by David Muir and Donald Trump. The researcher mainly utilized Pragmatics theory by Brown and Levinson which consists of four strategies, there are positive politeness, negative politeness, bald on record, and off record but, the researcher only focuses in positive politeness. As the methodology, the researcher used descriptive-qualitative approach to concern the description and the interpretation of Donald Trump videos. Under descriptive-qualitative method, this research significantly gives a wider understanding about how linguistic subjects emerges through pragmatics structure. The researcher gathered the data by downloading the interviews of Donald Trump on ABC News and in Charlie Rose Show, also the factors that influenced positive politeness used by David Muir and Donald Trump. As the result, there are 28 data were collected in this research and contained 10 types of positive politeness strategies based on Brown and Levinson’s theory. Moreover, there are two factors that influenced David Muir and Donald Trump. Those are social distance and relative power. Keywords: Pragmatics, Politeness Strategy, Positive Politeness, Donald trump, David Muir.Abstrakpenelitian ini meneliti ucapan Donald Trump dan David Muir di ABC News dan Charlie Rose Show. Peneliti juga memfokuskan pada strategi kesantunan positif yang digunakan oleh David Muir dan Donald Trump. Peneliti menggunakan teori pragmatik dari Brown and Levinson yang terdiri dari empat strategi yaitu, kesantunan positif, kesantunan negatif, ujaran secara langsung, ujaran secara tidak langsung. Tetapi, peneliti hanya lebih fokus di strategi kesantunan positif. Peneliti menggunakan metode deskriptif kualitatif yang berhubungan dengan deskripsi dan interpretasi dari video Donald Trump. Dengan menggunakan metode deskriptif kualitatif bisa memberikan pengertian lebih luas tentang pelajaran linguistik dengan melalui teori pragmatik. Peneliti memperolah data dengan mengunduh video wawancara Donald Trump di ABC News dan Charlie Rose Show dan ada dua faktor yang mempengaruhi David Muir dan Donald Trump. Sebagai hasil dari penelitian ini, peneliti menemukan 28 data yang terdapat di penelitian ini dan ada 10 macam srategi kesantunan positif. Selain itu ada 2 sebab yang mempengaruhi David Muir dan Donald Trump untuk melakukan strategi kesopanan positif yaitu jarak sosial dan kekuasaan tidak mutlak. Kata kunci: Pragmatik, Strategi Kesantunan, Kesantunan Positif, Donald Trump, David Muir.
Estimation of the cost price of the enterprise with the possibility of modeling contract positions
Authors: Damarad A. V. , Shcherbakova V. P. 
Published: December 2020

The need to account for cost price occupies an important place in the enterprise management system. One of the important tasks of accounting for cost price is to control the cost of production. The cost price includes the total costs necessary for the enterprise to carry out production and commercial activities related to the production and sale of products, that is, everything that the enterprise costs to produce and sell products.To determine the economic benefits of selling the company’s finished products, it is necessary to know the final cost of the proposed contract. The amount of profit directly depends on the correctness of setting the sales price of products. This article discusses the assessment of the economic effect when modeling various contract positions based on the cost price of the enterprise, which will allow you to quickly solve production issues.The source data is information stored in the SAP ERP (Enterprise Resource Planning System) system: materials, component lists, component standards, etc. The source data processing and analysis system is SAP BI (Business Intelligence). To display the final result, we use a program designed for working with Microsoft Excel spreadsheets.
Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro
Authors: Raut Snehal , Patel Ronak , Al-Ahmad Abraham 
Published: December 2020

Abstract
Background: Alzheimer’s disease (AD) is the most common form of neurodegenerative disease. It is an irreversible condition marked by irreversible cognitive loss, commonly attributed to the loss of hippocampal neurons due to the formation of senile plaques and neurofibrillary tangles. Although the sporadic form is the most prevalent, the presence of familial form (involving several genes such as APP, PSEN1, and PSEN2) of the disease is commonly used as a model for understanding the pathophysiology of the disease. The aim of this study is to investigate the effect of a mutation on PSEN1 and PSEN2 genes on the BBB function using induced pluripotent stem cells (iPSCs).Methods: iPSC lines from patients suffering from a familial form of Alzheimer’s disease and harboring mutations in PSEN1 or PSEN2 were used in this study and compared to a control iPSC line. Cells were differentiated into brain microvascular endothelial cells (BMECs) following established differentiation protocols. Barrier function was assessed by measuring TEER and fluorescein permeability, drug transporter activity was assessed by uptake assay, glucose uptake and metabolism assessed by cell flux analyzer, mitochondrial potential by JC-1, and lysosomal acidification by acridine orange. Results: iPSC-derived BMECs from the FAD patient presenting a mutation in the PSEN1 gene showed impaired barrier function compared to the FAD patient harboring a mutation in PSEN2 and to the control group. Such impaired barrier function correlated with poor tight junction complexes and reduced drug efflux pump activity. In addition, both PSEN1 and PSEN2-BMECs displayed reduced bioenergetics, lysosomal acidification, autophagy, while showing an increase in radical oxygen species (ROS) production. Finally, PSEN1- and PSEN2-BMECs showed an elevated secretion of Ab1-40 peptides compared to control-BMECs.Conclusion: Our study reports that iPSC-derived BMECs obtained from FAD patients showed impaired barrier properties and BMEC metabolism. In particular, mutation in the PSEN1 gene was associated with a more detrimental phenotype than mutation in PSEN2, as noted by a reduced barrier function, reduced drug efflux pump activity, and diminished glucose metabolism. Therefore, assessing the contribution of genetic mutations associated with Alzheimer’s disease will allow us to better understand the contribution of the BBB in dementia, but also other neurodegenerative diseases.
Glycyrrhizin improves the pathogenesis of psoriasis through IL-17A and the SIRT1-STAT3 axis
Authors: Qiong Huang , Han Ling , Zhang Nan , Chen Hu , Yan Ke , Zhang Zheng , Ma Ying , Xu Jin 
Published: December 2020

Abstract
Background: The anti-inflammatory effect of glycyrrhizin has been widely recognized, while the specific mechanism of glycyrrhizin in psoriasis remains poorly understood. Results: Here, in an imiquimd-induced mouse model of psoriasis (IMD), we found that glycyrrhizin can substantially improve the adverse symptoms in mice. The hematoxylin-eosin staining results showed that glycyrrhizin can also improve the pathological state of skin cells in IMD mice. Using enzyme-linked immunosorbent assay (ELISA), we found that glycyrrhizin substantially inhibited the expression of IL-17A and IFN-γ in the serum of IMD mice. In order to simulate the effect of IL-17A on keratinocytes in psoriasis, we treated HaCaT cells with 100 ng/mL IL-17A (IL-17A-HaCaT cells) for 48 h. Then, using cell-counting kit-8 (CCK-8) and ELISA assays, we found that glycyrrhizin inhibited the proliferation of IL-17A-HaCaT cells and reversed the promotion of IL-6, CCL20, and TNF-α induced by IL-17A. Further, western blotting (WB) results indicated that glycyrrhizin promoted the expression of SIRT1 and inhibited the expression of STAT3 and phosphorylated STAT3 (p-STAT3). By treating IL-17A-HaCaT cells with EX-527 (a potent and selective inhibitor of SIRT1), combined with CCK-8 and WB experiments, we initially found that EX-527 inhibited the proliferation of IL-17A-HaCaT cells and promoted the expression of STAT3, p-STAT3, and acetylated STAT3 (a-STAT3). However, when glycyrrhizin was added at the same time, the proliferation of IL-17A-HaCaT cells increased, and the expression of STAT3, p-STAT3, and a-STAT3 reduced. We then knocked down the expression of SIRT1 via small interfering RNA in IL-17A-HaCaT cells, and the results were consistent with those of EX-527. Conclusions: Together, these results indicated that glycyrrhizin improved psoriasis by inhibiting the expression of IL-17A and IFN-γ in vivo and suppressed the proliferation of IL-17A-HaCaT cells and the expression of STAT3, p-STAT3, and a-STAT3 by upregulating SIRT1 in vitro.
Quantitative assessment of the effectiveness of joint measures led by the Fangcang shelter hospitals in the response of COVID-19 epidemic in Wuhan, China
Authors: Jiang Hui , Song Pengfei , Wang Siyi , Yin Shuangshuang , Yin Jinfeng , Zhu Chendi , Cai Chao , Xu Wangli , Li Weimin 
Published: December 2020

Abstract
Objective

To quantitatively evaluate the effectiveness of Fangcang shelter hospitals, designated hospitals, and time interval from illness onset to diagnosis in the prevention and control of COVID-19 epidemic.
Methods

We use SEIAR and SEIA-CQFH warehouse models to simulate the two-stage epidemic in Wuhan and calculate the time dependent basic reproduction number (BRN) of symptomatic infected individuals, asymptomatic infected individuals, exposed individuals and community isolated infected individuals. Scenarios that varied in the maximum numbers of open beds in Fangcang shelter hospitals and designated hospitals, the intervals from onset to visit hospitals and diagnosis, are considered to quantitatively assess the optimal measures.
Findings:

The BRN is decreased from 4.50 on Jan 22 to 0.18 on March 18. Without Fangcang shelter hospitals, the case number of cumulative and death will increase by 18.58% and 51.73%. If the number of beds in the designated hospitals decrease by 1/2 or 1/4, the number of cumulative cases will increase by 178.04% and 92.1%. If the time interval from illness onset to hospital visit is 4 days, the number of cumulative cases and deaths will increase by 2.79% and 6.19%. If Fangcang shelter hospitals are not established, the number of beds in designated hospitals reduce 1/4 and the time interval from visiting hospitals to diagnosis is 4 days, the cumulative number of cases will increase 268.97%.