bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diş Aşınmaları Nedeniyle Dikey Boyut Kaybı Oluşan Hastanın Direkt Kompozit Restorasyonlar İle Rehabilitasyonu (Olgu Sunumu).
Authors: AL RAWİ Yasser İsmail , ÇETİN Ali Rıza 
Published: December 2019

Özet: Diş aşınmaları yaşlı hastalarda en sık karşılaşılan durumlardan biridir. Dikey boyut kaybı nedeniyle hem fonksiyonel hem de estetik problemleri neden olmaktadır. Normal dikey boyutu yeniden kazanabilmek için birkaç tedavi seçenekleri vardır. Sunulan vakada 51 yaşındaki erkek hastada yaygın diş aşınmaları ve çiğneme fonksiyonunda sorunlar mevcuttu. Dikey boyutun geri kazanılması amacıyla premolar dişlerin restorasyonu ile dikey boyut düzenlenmiş ve posterior dişler için implant destekli sabit protez yapılması planlanmıştır. Hastanın estetiğini düzeltmek, fonksiyona katkı sağlamak ve dikey boyutunun alışmasını kolaylaştırmak için üst alt anterior dişlere kompozit veneer restorasyonlar yapılmıştır. Bu restorasyonlar rehabilitasyonun ilk aşamasını oluşturacak ve hastanın planlanan tedavi sürecine alışmasını ve konforunu artıracaktır.Anahtar kelimeler: Diş Aşınmaları, Dikey Boyut Kaybı, Dental Kompozit. Abstract: Teeth wear is one of the most common conditions seen in elderly patients. Loss of normal occlusal vertical dimension can severely affect both function and esthetic. There are many approaches to regain the normal occlusal vertical dimension. In the presented case a 51 years old male patient had severe tooth wear in the maxillary and mandibular anterior teeth with loss of interocclusal space due to early loss of his posterior teeth. In order to regain the vertical dimension, premolar teeth were restored with composite restoration and the vertical dimension corrected for some extent, implant-supported fixed prosthesis was planned for the posterior area. For the anterior teeth, composite veneer restorations were made to upper and lower teeth in order to provide esthetic, function and to facilitate the patient’s adaptation of the increased vertical dimension. These restorations will create the first stage of rehabilitation and will increase the adaptation and comfort of the patient in the planned treatment process. Keywords: Tooth wear, Vertical Dimension Lose, Dental Composite.
Burnout in Pediatric Residents: Three Years of National Survey Data
Authors: Kemper Kathi J. , Schwartz Alan , Wilson Paria M. , Mahan John D. , Schubert Charles J. , Staples Betty B. , McClafferty Hilary , Serwint Janet R. , Batra Maneesh ,   PEDIATRIC RESIDENT BURNOUT-RESILIENCE STUDY CONSORTIUM
Published: December 2019

BACKGROUND:
We aimed to describe the national epidemiology of burnout in pediatric residents.

METHODS:
We conducted surveys of residents at 34 programs in 2016, 43 programs in 2017, and 49 programs in 2018. Survey items included the Maslach Burnout Inventory, demographics, program characteristics, personal qualities, experiences, and satisfaction with support, work-life balance, and learning environment. Analyses included cross-sectional comparisons and cross-sectional and longitudinal regression.

RESULTS:
More than 60% of eligible residents participated; burnout rates were &gt;50% in all years and not consistently associated with any demographic or residency characteristics. Cross-sectional associations were significant between burnout and stress, sleepiness, quality of life, mindfulness, self-compassion, empathy, confidence in providing compassionate care (CCC), being on a high-acuity rotation, recent major medical error, recent time off, satisfaction with support and career choice, and attitudes about residency. In cross-sectional logistic regression analyses, 4 factors were associated with an increased risk of burnout: stress, sleepiness, dissatisfaction with work-life balance, and recent medical error; 4 factors were associated with lower risk: empathy, self-compassion, quality of life, and CCC. Longitudinally, after controlling for 2017 burnout and 2018 risk factors (eg, recent error, sleepiness, rotation, and time off), 2017 quality of life was associated with 2018 burnout; 2017 self-compassion was associated with lower 2018 stress; and 2017 mindfulness, empathy, and satisfaction with learning environment and career choice were associated with 2018 CCC.

CONCLUSIONS:
A majority of residents met burnout criteria. Several identified factors (eg, stress, sleepiness, medical errors, empathy, CCC, and self-compassion) suggest targets for interventions to reduce burnout in future studies.
Retratos profanados: uma análise sobre morte e fotografia na poesia de Carlos Drummond de Andrade
Authors: Rocha Mariane Pereira , Martins Aulus Mandagará 
Published: December 2019

O presente artigo tem como objetivo identificar as funções que a fotografia desempenha na relação que o eu-lírico drummondiano estabelece com os mortos nos poemas “Os mortos” de Lição de coisas (1962), “Os mortos de sobrecasaca” de Sentimento do mundo (1940), “Os rostos imóveis” de José (1940) e “Necrológio dos desiludidos do amor” de Brejo das almas (1932), a partir da perspectiva de Giorgio Agamben (2007) Susan Sontag (2004), Georges Didi-Huberman (1998) e Joan Fontcuberta (2010), utilizando a metodologia bibliográfica na perspectiva dos estudos comparados. Discute-se, assim, que indo na contramão do discurso comum sobre a fotografia, em que ela é vista como mera representação da realidade ou como um registro fiel e confiável do passado, a fotografia, enquanto temática drummondiana, vai se apresentar como um dispositivo frágil e que constantemente o relembra da impossibilidade da permanência da memória, contribuindo para um contínuo desencontro do eu-lírico com os mortos, que se manifesta em um tom irônico e de afronta, bem como em uma dificuldade de elaborar o passado.
Ilustração e complementariedade fotoliterária: o caso de Nadja, de André Breton
Authors: Estanislau de Ataíde Mantovani Juliana 
Published: December 2019

Este artigo se propõe a descrever e a analisar as relações fotoliterárias presentes em Nadja (1928), primeira narrativa em prosa de André Breton, bem como os efeitos dos sentidos gerados no todo da obra. Em nossa discussão, nos fundamentaremos nos conceitos basilares da Fotoliteratura (MONTIER, 2008 e 2015) e faremos a análise pontual desse livro, com ênfase em alguns excertos textuais e em algumas imagens fotográficas inseridas na obra bretoniana. Nessa perspectiva, refletiremos também sobre o potencial conotativo da fotografia e, por fim, objetivaremos – a partir de tais investigações – a compreender as interações e as interferências estabelecidas entre o texto e a imagem, com a finalidade de defender a existência nessa obra de uma forma de ilustração em complementariedade.
Vulnerabilidades en salud de garimpeiros de una región amazónica
Authors: Ferreira do Nascimento Vagner , Gineli de Jesus Walber , Pereira Terças-Trettel Ana Cláudia , Yuri Hattori Thalise , Benevenuto Reis Juliana , Roma Greve Nodari Poliana 
Published: December 2019

El objetivo del estudio fue identificar las vulnerabilidades en salud de los garimpeiros de una región amazónica. Se trata de un estudio exploratorio y cualitativo, realizado en un garimpo en la Amazonia Legal, en el interior de Rondônia, Brasil, en marzo de 2017. Se realizaron entrevistas semiestructuradas y los datos empíricos obtenidos fueron transcritos en su totalidad y sometidos al análisis de contenido. Se evidenció que la actividad garimpeira amplía la situación de vulnerabilidad del trabajador, acercándolo a situaciones de enfermedad, especialmente por la no adopción de medidas preventivas. A pesar de que las vulnerabilidades que la actividad implica, condiciones peligrosas e insalubridad en el trabajo, los garimpeiros no desean abandonar el garaje. La vulnerabilidad de estos garimpeiros es agravada por tener poco conocimiento sobre los factores de riesgo, como el contacto directo y prolongado con el agua, exposición solar e inutilización de EPI, por no disponer de servicio de salud y no realizar prácticas seguras de autocuidado. Al término del estudio, se notó que la existencia de actuales políticas del sector, no garantizan condiciones de vida, salud y acceso a los servicios públicos, lo que sostiene la vulnerabilidad de esos trabajadores.
Percepção de adolescentes escolares masculinos quanto ao cuidado à sua saúde
Authors: Carvalho Ana Carolina Tavares de , Silva Darine Marie Rodrigues da , Brandão Neto Waldemar , Pereira Emanuela Batista Ferreira e , Menezes Maria Lúcia Neto de , Aquino Jael maria de 
Published: December 2019

Objetivo: comprender las percepciones de los adolescentes escolares de sexo masculino sobre el cuidado de su salud. Métodos: estudio descriptivo, con abordaje cualitativo, realizado con 32 estudiantes de una escuela pública estadual del municipio de Recife-PE. Para la recolección de datos se empleó una entrevista semiestructurada, siendo las declaraciones descompuestas y organizadas mediante la técnica del Discurso del Sujeto Colectivo. Resultados: Surgieron cinco Ideas Centrales resultado de los DSC: Busca de los adolescentes por aclaraciones de dudas y cuestiones de salud, Actuación de la escuela en la estrategia de educación en salud, Percepción de los adolescentes en relación al concepto de salud, Comportamiento de los adolescentes en el cuidado a la salud, Busca por mejoras en las condicione de salud. Conclusión: Fue evidenciado que la participación de la familia, escuela y profesionales de salud, especialmente los de enfermería ejercen importante influencia en el proceso de formación del adolescente. En este sentido, es fundamental la implicación de estos actores para el fortalecimiento de acciones de promoción de la salud y autocuidado de los adolescentes.
NEUROIMMUNOENDOCRINE REGULATION OF THE SKIN FUNCTIONING
Authors: Bashkina O. A. , Samotrueva M. A. , Azhikova A. K. , Paknnova L. R. 
Published: December 2019

The review deals with modern ideas of neuroimmunoendocrine regulation of physiological and pathophysiological processes in skin. The present data are provided which indicate to composite mechanisms of intercellular interactions in complex regulating systems (nervous, immune, endocrine) acting at the level of skin in normal conditions, as well during the posttraumatic period. We describe different modes for participation of endocrine and nervous systems in immunologically induced skin inflammation. The data are provided confirming localization of adrenergic receptors on membranes of immunocompetent cells and leukocytes, on regulatory effects of hypothalamus upon immune functions, about multidirectional actions upon inflammation of sympathetic and parasympathetic nervous system etc.There are sufficient data on promotion of pathophysiological changes and reconstitution processes in the skin due to effects of local immune cells and bioactive substances expressed by them. The course of skin wound regeneration depend on the type of damage, degree and a phase of healing process. Posttraumatic reparative potential of skin is often limited by the infectious processes initiated by local microflora, products of cell disintegration and necrotic tissues. The cause-effect relationship is proven by arising inflammation which is implemented by inclusion of immune protection responses. The increased necrotic area and suppuration of the wound occurs die to inhibition of system of the phagocytizing macrophages. However, activation of this system brings about formation of the connective tissue capsule around the inflammation focus within early terms.We also discuss the issues of reparative skin regeneration which of great medico-social value, in connection with considerable prevalence of traumatic events and their social consequences, followed by expressed cosmetic defects. Evolving neurocognitive problems lead to decreased quality of the patient’s life, development of social disadaptation and further deprivation. The role of nervous system and psychological frustration in genesis of skin manifestations requires future development of the modern scientific direction, i.e., psychodermatology.Understanding of molecular mechanisms regulating the neuroimmunocutaneous interactions offers new prospectives in treatment of some skin diseases, as well as activation of the damaged skin recovery. According to the data presented in the review article, one may conclude on relevance of further studies on reparative potential of skin under interactions of homeostatic regulatory systems.
CHARACTERISTICS OF AUTOIMMUNE INFLAMMATION IN THE PATIENTS WITH LUNG TUBERCULOSIS
Authors: Starshinova A. A. , Malkova A. М. , Zinchenko Yu. S. , Basantsova N. Yu. , Pavlova M. V. , Belyaeva E. N. , Lapin S. V. , Masing A. V. , Surkova E. A. , Yablonsky P. K. 
Published: December 2019

Tuberculosis is a granulomatous disease caused by Mycobacterium tuberculosis, being characterized by the development of caseous granulomas in various organs, mainly in lungs. M. tuberculosis is known to be a trigger for autoimmune inflammation, due to the possible mimicry of bacterial proteins as autoantigens. Recently, a significance of mesenchymal vimentin as an autoantigen in mycobacterial infections has been actively discussed. The aim of the present study was to determine autoantibodies for various vimentin modifications in the patients with tuberculosis.The study was performed in 2014-2017 and included 28 patients with pulmonary tuberculosis (group I), 30 patients with nonspecific lung diseases (group II): 15 with granulomatous polyangiitis, and 15 with different alveolites. Control group consisted of healthy subjects (n = 40). Concentration of antibodies to mutated citrullinated vimentin (anti-MCV) was measured using ELISA (ORGENTEC, Germany). The patients with elevated anti-MCV levels were tested for antibodies to cyclic citrullinated peptide (anti-CCP) using ELISA technique (EUROIMMUN, Germany). Statistical analysis was carried out using GraphPad Prism 6 (GraphPad Software, USA), Statistica 10 (Statsoft, USA) using nonparametric analysis of samples with Mann-Whitney and Chi-square criteria, and Spearman method for correlation analysis. The differences were considered statistically significant at p < 0.05.The anti-MCV concentrations were significantly higher in patients with tuberculosis (group I, 60.7% of cases, 17/28) than in group II, and control group (23.6 and 25.0% of cases, respectively). No statistically significant differences were revealed between the results of anti-MVC and anti-CCP levels in comparison group with the control group (p = 0.18).High levels of anti-MCV antibodies in the patients with pulmonary tuberculosis reflect an opportunity of developing autoimmune process in the disease pathogenesis. Measurement of plasma anti-MCV antibody concentrations may be important for correction of the therapy, especially upon administration of immunosuppressive and hormonal corticosteroid drugs. It has been shown that anti-CCP are not characteristic to the lung diseases.
Reindeer carcasses provide foraging habitat for insectivorous birds of the alpine tundra
Authors: Badia Rudy , Steyaert Sam MJG , Puliti Stefano , Blaalid Rakel , Frank Shane C 
Published: December 2019

On August of 2016, almost an entire herd (n = 323) of wild tundra reindeer (Rangifer tarandus) was killed by lightning on Hardangervidda in southern Norway. While conducting fieldwork for another study in 2017, we opportunistically registered the occurrence and behaviour of birds on carcasses from this mass die-off. Several passerine species other than corvids were observed actively foraging on arthropods, such as blowfly (Calliphoridae sp.) adults and larvae, which are typically associated with carcass decomposition. We quantified observations of those birds, and described their foraging behaviour at the carcass site. In decreasing order of abundance, five passerine species were observed taking arthropods at the site: Meadow Pipit (Anthus pratensis), Northern Wheatear (Oenanthe oenanthe), Common Reed Bunting (Emberiza schoeniclus), Bluethroat (Luscinia svecica,), and Lapland Bunting (Calcarius lapponicus). Systematic surveys of passerines utilizing carcass sites would further our understanding of how such resources may affect behaviour and life history of various bird species.
Identification of a new methylation site in the Sept9 promoter region for the diagnosis of hepatocellular carcinoma
Authors: Lazarevich N. L. , Abramov P. M. , Fedorova M. D. , Kustova I. F. , Shavochkina D. A. , Katargin A. N. , Kisseljova N. P. , Dyakova N. A. , Botezatu I. V. , Kondratova V. N. , Kudashkin N. E. , Patyutko Yu. I. , Lichtenstein A. V. , Vinokurova S. V. 
Published: December 2019

Background. Over 600,000 people die from hepatocellular carcinoma (HCC) each year worldwide. The disease is often detected at advanced stages and in many cases is not curable. Early diagnostic and monitoring of HCC recurrences remains a substantial problem in clinical oncology. That determines the need for a search for highly sensitive and specific biomarkers for the non-invasive of HCC diagnostics. The objective of the study. Identification of the hypermethylated locus in the promoter region of the septin 9 (Sept9) gene based on the annotated methylomes from the public databases. Experimental validation of methylation on a pilot panel of paired clinical samples of patients with HCC, as well as tissue samples from patients with benign liver tumors and lymphocytes from healthy donors. Materials and methods. To analyze the methyl data, samples of HCC from TCGA, hepatocellular adenoma from GEO (Gene Expression Omnibus) depository, peripheral blood cells and tissues of healthy donors from Methbank were used. Experimental validation of methylation levels of the identified site was carried out on a pilot panel of clinical samples by bisulphite pyrosequencing using PyroMark Q24.Results. Based on the analysis of methylome data, we selected cg20275528 site, which is characterized by high level of methylation in HCC tissues and minimal levels of methylation in non-tumor liver tissue, hepatocellular adenoma and peripheral blood of healthy donors. Experimental testing on a pilot panel of clinical specimens showed that the level of marker site methylation in HCC (42 % median) is significantly higher than in non-tumor liver tissues (3 % median) and benign neoplasms (1.5 % median) and exceeds the threshold value in HCC compared to paired samples of adjacent non-tumor liver tissue in 20 out of 30 studied cases (66.6 %). The general possibility for cg20275528 methylation detection in circulating DNA of plasma in HCC patients was shown.Conclusion. The obtained results indicate that the approach to the detection and experimental verification of diagnostically significant markers developed and tested in this study can be used to identify new differentially methylated sites and to establish new approaches for non-invasive HCC diagnosis.
Determination of chemoresistance of ovarian cancer cells in vitro
Authors: Kuzin K. A. , Fetisov T. I. , Knyazev R. I. , Fomina L. Ya. , Meheda L. V. , Lesovaya E. A. , Belitsky G. A. , Yakubovskaya M. G. , Kirsanov K. I. 
Published: December 2019

Objectives: to provide a rationale for existing approaches for the evaluation of chemoresistance of ovarian cancer in vitro, to perform a comparative analysis of the methods and to assess the perspectives of their further application.Materials and methods. For the review preparation, we analyzed articles on experimental testing of ovarian cancer resistance to chemotherapeutic agents, available at biomedical literature databases SciVerse Scopus (158), PubMed (323), Web of Science (285), RSCI (64). The review cited 37 recent publications, 12 of them being published over the past three years, and 16 articles being referred as pioneer publications on techniques previously and used today.Results. Peculiarities of the main methods for assessing the resistance and sensitivity of a cancer to various chemotherapeutic drugs using primary cultures of tumor cells obtained from biopsy or surgical material are analyzed. Proliferative and metabolic activities as well as the level of cell death were considered as the main evaluated characteristics of tumor cells. The methodological features of the described methods are discussed, as well as the prospects for their further application.Conclusion. Predictive detection of chemoresistance of ovarian cancer is based on testing the viability of tumor cells in the presence of a chemotherapeutic drug. The results of studies of the key mechanisms of chemoresistance development in tumor cells provide the rationale for improving in vitro testing.
ANALISIS BUDAYA ORGANISASI TERHADAP MOTIVASI KERJA DALAM MENINGKATKAN KINERJA KARYAWAN FIS UNIVERSITAS NEGERI MALANG
Authors: Az zuhri Fahmi Muhammad , Permanasari Kartika Indah Permanasari 
Published: December 2019

Kinerja karyawan yang optimal merupakan salah satu sasaran organisasi untuk mencapai produktivitas kerja yang tinggi. Sikap mental karyawan yang pro dan positif terhadap situasi kerja itulah yang memperkuat motivasi kerjanya untuk mencapai kinerja maksimal. Tujuan penelitian ini adalah untuk mengetahui apakah ada pengaruh langsung antara Budaya Organisasi terhadap Kinerja karyawan Fakultas Ilmu Sosial Universitas Negeri Malang dan untuk mengetahui apakah ada pengaruh tidak langsung antara Budaya Organisasi terhadap Kinerja Karyawan Fakultas Ilmu Sosial Universitas Negeri Malang melalui Motivasi kerja Karyawan. Jumlah sampel yang digunakan adalah 99 responden. Alat analisis yang digunakan adalah Path Analysis. Hasil menunjukkan bahwa terdapat pengaruh langsung yang signifikan antara budaya organisasi terhadap kinerja karyawan FIS UM. Terdapat pengaruh tidak langsung antara budaya organisasi terhadap kinerja karyawan melalui motivasi karyawan
The benefits of Functional Movement Screen in judo
Authors: Simenko Jozef 
Published: December 2019

With the development of screening methods, simple screening tools could commonly be used to assess movement quality in real-world conditions. One of those methods is the functional movement screen (FMS), that was developed to helps determine the fundamental movement patterns of an individual. FMS test was administered to 9 elite judokas aged 22 ± 4.24 years, height 176.44 ± 7.44 and weight 79.44 ± 15.92 kg. The overall FMS score was 17.56 ± 1.59. No significant asymmetries were noted in the bilateral test. The lowest score was achieved in shoulder mobility 1.89 ± 0.6 which represent and issue that needs to be addressed to prevent the occurrence of injuries. Overall the FMS testing could be a beneficial tool to strength and conditioning coaches in judo, especially in the preseason to assess the functional movement status of judo athletes and to address any issues that could be identified. It represents a fast and affordable screening tool, but it needs to be administered by a qualified assessor. The data of this study could serve as a reference score to other FMS research in judo or other combat sports or martial arts.