bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of tissue Doppler imaging in the assessment of diastolic dysfunction in children with chronic lung diseases
Authors: Draz Iman H. , Mostafa Fatma El Zahraa , AbdelMassih Antoin F. , El-Sayed Dalia , El-Kaffas Rania 
Published: June 2020

AbstractBackgroundChronic lung diseases (CLD) in children such as bronchiectasis and interstitial lung disease represent a major public health problem with limited therapeutic options. These patients develop pulmonary hypertension (and core-pulmonale in severe cases) because of the recurrent hypoxia and chronic inflammation; which results in right heart enlargement and ventricular hypertrophy. The early identification and convenient treatment of diastolic dysfunction can prevent further complications of the disease including diastolic heart failure and death. We aim to demonstrate the usefulness of tissue Doppler imaging echocardiography (TDI) in the detection of subtle myocardial affection in interstitial lung disease and bronchiectasis as subgroups of (CLD) in children. We studied echocardiographic parameters of 40 pediatric patients with chronic lung disease using conventional M mode and tissue Doppler imaging and compared them with 40 healthy controls of matching age and sex distribution.ResultsMyocardial performance index (MPI) showed that 28 subjects had abnormal right ventricular (RV) MPI (10 with severe affection ≥ 0.6) and 21 subjects had abnormal LV MPI (11 severe affections ≥ 0.6). Thirty percent (30%) of the cases had affected lateral E/E' and 47.5% had affected septal E/E' when compared to controls. Grades of diastolic dysfunction were: 0, 1, 2, 3 in 18, 15, 6, and 1 patients, respectively. MPI LV and MPI RV showed statistically higher values in patients compared to controls (P< 0.001).ConclusionThis study proved that TDI can accurately detect subtle myocardial dysfunction in pediatric CLD patients.
Assessment of the validity of image-defined risk factors (IDRFs) in abdominal neuroblastoma
Authors: Mohamed Ahmed Hassan Ali , Mahmoud Ikram Hamed , Seif El Dein Hadeel Mohammed , Sallam Kareem Raouf , Wahba Hisham Samir 
Published: June 2020

Abstract
Background
Neuroblastoma is the third most common childhood cancer. It is the most common extra-cranial solid tumor of childhood. It accounts for about 15% of all pediatric cancer fatalities.
The International Neuroblastoma Risk Group (INRG) Project proposed a new staging system which is dependent on whether image-defined risk factors (IDRFs) are or are not present, and IDRFs are surgical risk factors, detected on images, that make total tumor excision risky or difficult.
The purpose of the study is to assess the validity of using the image-defined risk factors (IDRFs) of abdominal neuroblastoma as predictors of the surgical resectability and complications.

Methods
We retrospectively studied the clinical, imaging, and surgical data of 43 patients with abdominal neuroblastoma, and then the results were correlated with each. For comparing categorical data, chi-square (χ2) test was performed. P values less than 0.05 were considered as statistically significant.

Results
At least 1 pre-operative IDRF was present in 33 cases (76.7%), and they were absent in 10 cases (23.3%). There was statistical significant correlation between the pre-operative IDRFs and surgical resectability, and the complete resection rate if no IDRF was found was 80% in this study. Out of the 13 cases with surgical complications, pre-operative IDRFs were present in 12 cases.

Conclusion
The neuroblastoma IDRFs are useful predictors of the surgical resectability and the risk of surgical complications and should be considered in surgical planning.
Urban Pedogeneses
Authors: Meulemans Germain 
Published: June 2020

AbstractThis article examines the rise of urban soils as a topic of scientific inquiry and ecological engineering in France, and questions how new framings of soil as a material that can be designed reconfigure relationships between urban life and soils in a context of fast-growing cities. As a counterpoint to the current situation, the article first examines how the hard-surfacing of Paris, in the nineteenth century, sought to background the vital qualities of soils in urban areas, making their absence seem perfectly stable and natural. It then shows how the new urban soil science moved away from classical descriptive approaches to soils, and set out to fabricate soils as a research experiment on anthropo-pedogenesis. In the French context, urban soil scientists soon formed new bonds with the worlds of urbanism, administration, and waste management, reframing their approach as a technical response to issues brought by sprawling cities, backgrounding soils again under a trope centered on the management of soil services. These stories allow to critically inhabit soil scientists’ claim that humans participate in pedogenesis by examining the specific conditions in which modern modes of being in the world and urban soils become entangled or disentangled in modern metropolis.
Ethical Acknowledgment of Soil Ecosystem Integrity amid Agricultural Production in Australia
Authors: O’Brien Anne Therese 
Published: June 2020

AbstractThe growing adoption of no-till cropping and other minimal-impact farming practices in recent decades signals a shift in how soil is understood and valued. Eschewing vigorous disturbance, standard in the West (and beyond) since the Neolithic Revolution, farmers instead learn to intervene with the soil profile more sensitively. This article focuses on the concept of soil integrity and its significance for farmers’ ethical relationship to soils in everyday practice, using the case study of pasture cropping, an Australian form of agriculture that extends no-till methods to embrace ecological relationships within and beyond the soil. Prioritizing the integrity of soil ecosystems often requires reconceiving what soil is and should be. Soil can be difficult to see as ethically significant partly because it often appears as a granular bulk good, seemingly featureless and fungible. To counteract this, farmers who care for soil integrity use various heuristic and aesthetic strategies to render soil integrity more perceptible and intelligible. The author considers how a keener perception of soil integrity may enable greater attunement toward the soil condition, acknowledgement of soil distress, and thus ethical responsiveness. The article considers this through a broader discussion of phenomenological ethics.
Everyday Ecocide, Toxic Dwelling, and the Inability to Mourn
Authors: Jones Owain , Rigby Kate , Williams Linda 
Published: June 2020

Abstract
In responding to the spatiotemporally specific geographies of extinction charted in the articles in this special section, this article reflects on the sociocultural factors that inform the ways in which extinction is framed and impede recognition of the enormity of the anthropogenic extinction event in which we are all bound. This article argues that we are living in an era of ecocide, where the degradation of biodiversity and eradication of species go hand-in-hand with the degradation and eradication of nonmodern culture and identity, and it explores some possible reasons why modern society is failing to respond to impending crisis. Fine-grained stories of spatiotemporally specific geographies of extinction can help to counter the logic of colonization and bring everyday ecocide into view. For the particular multispecies communities they concern, they can also feed into the creation of ritual practices of penitential mourning in ways that enable a collective grieving process poised to activate an ecosocial transformation. The authors consider the implications of grief and mourning—and of not mourning—in what can be seen as not only a terrible time but also the end of (lived) time. They conclude with some reflections of local acts of resistance, witnessing, and narrative.
Dynamic neurotransmitter specific transcription factor expression profiles during Drosophila development
Authors: Estacio-Gómez Alicia , Hassan Amira , Walmsley Emma , Le Lily Wong , Southall Tony D. 
Published: June 2020

ABSTRACT
The remarkable diversity of neurons in the nervous system is generated during development, when properties such as cell morphology, receptor profiles and neurotransmitter identities are specified. In order to gain a greater understanding of neurotransmitter specification we profiled the transcription state of cholinergic, GABAergic and glutamatergic neurons in vivo at three developmental time points. We identified 86 differentially expressed transcription factors that are uniquely enriched, or uniquely depleted, in a specific neurotransmitter type. Some transcription factors show a similar profile across development, others only show enrichment or depletion at specific developmental stages. Profiling of Acj6 (cholinergic enriched) and Ets65A (cholinergic depleted) binding sites in vivo reveals that they both directly bind the ChAT locus, in addition to a wide spectrum of other key neuronal differentiation genes. We also show that cholinergic enriched transcription factors are expressed in mostly non-overlapping populations in the adult brain, implying the absence of combinatorial regulation of neurotransmitter fate in this context. Furthermore, our data underlines that, similar to Caenorhabditis elegans, there are no simple transcription factor codes for neurotransmitter type specification.
This article has an associated First Person interview with the first author of the paper.
LA BONNE FOI ET LE PRECEDENT: BHASIN C. HRYNEW ET LA COMMON LAW CANADIENNE
Authors: Pallard Henri R. , Giroux Michel 
Published: June 2020

En common law canadienne, la bonne foi dans les obligations contractuelles se limite à des domaines précis ; il n’y a pas d’obligation générale. Dans Bhasin c. Hrynew, la Cour suprême du Canada à cherché à pallier cette insuffisance en posant un principe directeur général de bonne foi et une obligation d’agir honnêtement dans l’exécution de ses obligations contractuelles. Elle laissait aux cours inférieures la tâche de déterminer les modalités de mise en application du nouveau principe. La Cour a utilisé la méthodologie de la common law pour sortir des limites analytiques restreintes de la common law et élargir la portée de la bonne foi. Or ce précédent n’a pas eu l’effet escompté. La définition limitée de la bonne foi donnée par la Cour suprême du Canada a conduit les cours inférieures à réduire Bhasin c. Hrynew à un cas d’espèce. Devant l’indétermination du principe et de sa portée, les cours d’appel ont utilisé une gamme de techniques pour le distinguer, entre autres, un recours aux règles de la common law pour limiter son champ d’application au lieu d’un recours à la nouvelle décision pour modifier les règles de la common law. Le Uniform Commercial Code (UCC) et le Code civil du Québec (CCQ), auxquels la Cour s’était référée pour justifier l’introduction du principe directeur général en common law fournissait une feuille de route pour son élaboration que les juridictions inférieures ont refusé de suivre.
OS MANIFESTOS DE CRIAÇÃO DE CRIPTOMOEDAS: ELEMENTOS POLÍTICO-IDEOLÓGICOS NOS WHITE PAPERS E SUA CONSIDERAÇÃO POR REGULADORES
Authors: Quirino Carina De Castro , Cunha Marcella Brandão Flores da 
Published: June 2020

O artigo busca identificar se os white papers que acompanham o lançamento de criptomoedas trazem discursos/posicionamentos meramente técnicos. A pesquisa se justifica por haver uma crescente discussão a respeito da regulação de criptomoedas, diante de um cenário em que parecem ter sido criadas justamente para se afastarem da longa manus do Estado. Em um primeiro momento, foi analisada a conceituação de white paper e seus propósitos, para que então se pudesse compreender o que, de fato, é o mais relevante da pesquisa: o conteúdo de white papers lançados com as criptomoedas de maior market cap no momento de realização da pesquisa, de modo a aferir se era possível identificar a presença de conteúdo político-ideológico aliado ao conteúdo técnico nesses documentos. Em razão do resultado apresentado, considera-se que elementos político-ideológicos em white papers podem servir ao agente regulador no seu processo de tomada de decisão, seja para decidir regular ou não criptomoedas, mas também para definir os limites de sua atuação.
LEGALIMPLICATIONS OF STREET ART AS A ‘DEMOCRATIZED’/’OPEN’ FORM OF ART
Authors: Bastos Fernando Loureiro 
Published: June 2020

The prestige of street art as an artistic expression has increased year after year. The analysis of its legal implications must take into account the difficulties in reaching a general operative concept of street art and the need to legally frame the creation, preservation and transaction of street art productions. Since the legal concept is not equivalent to the theoretical concept or the history of art, each State and even each municipality can create their own legal concepts, acting in accordance with these specific concepts in order to control production, to punish execution as vandalism or, in contrast, to protect works produced as part of their cultural heritage. Although street art is created in and for open spaces, usually as an ephemeral art, the commercial interest in street art productions raises questions of due diligence during its transaction, such as those related to ownership, authenticity and even provenance. As an expression of an artistic movement started about half a century ago, can street art works be equated with “traditional” works of art (such as “goods” or “merchandises”), being subject to ownership, commercial sale and copyright, or must they be appreciated as artifacts that can be preserved as part of the cultural heritage or, alternatively, starting from the specific artistic and creative intent of the artist, be understood as a type of works of art that require the creation of new legal categories and forms of understanding its meaning?
Impact of 1.5 oC and 2 oC global warming scenarios on malaria transmission in East Africa
Authors: Ogega Obed Matundura , Alobo Moses 
Published: June 2020

Background: Malaria remains a global challenge with approximately 228 million cases and 405,000 malaria-related deaths reported in 2018 alone; 93% of which were in sub-Saharan Africa. Aware of the critical role than environmental factors play in malaria transmission, this study aimed at assessing the relationship between precipitation, temperature, and clinical malaria cases in E. Africa and how the relationship may change under 1.5 oC and 2.0 oC global warming levels (hereinafter GWL1.5 and GWL2.0, respectively). Methods: A correlation analysis was done to establish the current relationship between annual precipitation, mean temperature, and clinical malaria cases. Differences between annual precipitation and mean temperature value projections for periods 2008-2037 and 2023-2052 (corresponding to GWL1.5 and GWL2.0, respectively), relative to the control period (1977-2005), were computed to determine how malaria transmission may change under the two global warming scenarios. Results: A predominantly positive/negative correlation between clinical malaria cases and temperature/precipitation was observed. Relative to the control period, no major significant changes in precipitation were shown in both warming scenarios. However, an increase in temperature of between 0.5 oC and 1.5 oC and 1.0 oC to 2.0 oC under GWL1.5 and GWL2.0, respectively, was recorded. Hence, more areas in E. Africa are likely to be exposed to temperature thresholds favourable for increased malaria vector abundance and, hence, potentially intensify malaria transmission in the region. Conclusions: GWL1.5 and GWL2.0 scenarios are likely to intensify malaria transmission in E. Africa. Ongoing interventions should, therefore, be intensified to sustain the gains made towards malaria elimination in E. Africa in a warming climate.
Second-harmonic generation and manipulation in lithium niobate slab waveguides by grating metasurfaces
Authors: Fang Bin , Li Hanmeng , Zhu Shining , Li Tao 
Published: June 2020

Nonlinear optical processes in waveguides play important roles in compact integrated photonics, while efficient coupling and manipulations inside the waveguides still remain challenging. In this work, we propose a new scheme for second-harmonic generation as well as beam shaping in lithium niobate slab waveguides with the assistance of well-designed grating metasurfaces at

λ
=
1064

nm

. By encoding the amplitude and phase into the holographic gratings, we further demonstrate strong functionalities of nonlinear beam shaping by the metasurface design, including dual focusing and Airy beam generation. Our approach would inspire new designs in the miniaturization and integration of compact multifunctional nonlinear light sources on chip.
Pasang Surut, Arus dan Gelombang Berdasarkan Data Pengukuran Acoustic Doppler Current Profiler di Perairan Pulau Cilik, Karimunjawa
Authors: Indrayanti Elis , Wijayanti Diah Permata , Siagian Hendry Syahputra Ropinus 
Published: June 2020

Pulau Cilik merupakan gugusan pulau di Karimunjawa yang menjadi salah satu destinasi wisata bahari di Indonesia. Perairan ini kaya akan terumbu karang dan ikan berwarna-warni dengan tutupan karang hidup yang masih tinggi. Proses hidrodinamika seperti pasang surut, arus laut dan gelombang laut secara langsung maupun tidak langsung berpengaruh terhadap kondisi terumbu karang, oleh karena itu penelitian ini perlu dilakukan. Tujuan penelitian adalah untuk mengetahui karakteristik pasang surut, arus laut dan gelombang berdasarkan data pengukuran Acoustic Doppler Current Profiler (ADCP) di Perairan Pulau Cilik, Karimunjawa. Pengukuran dilaksanakan selama 7x24 jam dengan interval waktu 600 dt dan sample rate 300 dt. Posisi ADCP pada -5.8177°S dan 110.5096°E. Kedalaman total pengukuran 14 m dengan kedalaman aktif pengukuran 12 m, yang terbagi menjadi 6 lapisan kedalaman yaitu 2 m, 4 m, 6 m, 8 m, 10 m, dan 12 m. Hasil pengukuran menunjukkan bahwa Perairan Pulau Cilik, Karimunjawa memiliki tipe pasang surut campuran condong harian tunggal dengan nilai formzahl sebesar 2.55. Kecepatan arus bervariasi dengan rata-rata pada seluruh lapisan antara 5.57–6.35 cm/dt, sedangkan arahnya bi-directional yaitu memiliki dua muka arah (timur dan barat-barat daya). Tinggi dan periode gelombang yang didapatkan pada saat pengamatan relatif kecil. Cilik Island Waters in Karimunjawa is one of the marine tourism destinations in Indonesia. These waters are rich in coral reefs and colorful fish with high live coral cover. Hydrodynamic processes as tides, ocean currents, and waves influence the performance of coral reef through direct or indirect effects. Therefore this research needs to be done. The purpose of this study was to determine the characteristics of tides, ocean currents, and waves based on Acoustic Doppler Current Profiler (ADCP) measurement data in Cilik Island Waters, Karimunjawa. Measurements were carried out for 7 x 24 hours (2 April 2017 - 9 April 2017) with a time interval of 600 s and a sample rate of 300 s. The ADCP position is -5.8177 ° S and 110.5096 ° E. The total depth is 14 m with an actual measurement depth of 12 m, which is divided into 6 layers of depth namely 2 m, 4 m, 6 m, 8 m, 10 m, and 12 m. Result shown that Cilik Island, Karimunjawa, have a single mixed daily tidal type with a formzahl value of 2.55. Current velocity varies with the average in all layers between 5.57-6.35 cm/s, while the direction is bi-directional, which has two faces (east and west-southwest). The height and wave period obtained at the time of observation are relatively small.
Constant sign and nodal solutions for superlinear (p, q)–equations with indefinite potential and a concave boundary term
Authors: Papageorgiou Nikolaos S. , Zhang Youpei 
Published: June 2020

Abstract
We consider a nonlinear elliptic equation driven by the (p, q)–Laplacian plus an indefinite potential. The reaction is (p − 1)–superlinear and the boundary term is parametric and concave. Using variational tools from the critical point theory together with truncation, perturbation and comparison techniques and critical groups, we show that for all small values of the parameter, the problem has at least five nontrivial smooth solutions, all with sign information and which are linearly ordered.
New genetic diversity for endangered bottlenose dolphin subspecies along the Argentine coast
Authors: Loizaga Rocío , Grandi Florencia , Cunha Haydée , Crespo Enrique 
Published: June 2020

Abstract
This study analyzed mtDNA sequences of two bottlenose dolphin subspecies found along the northern Patagonian coast, Argentina: the endangered Tursiops truncatus gephyreus and the data deficient Tursiops truncatus truncatus. Three haplotypes were recovered from nine samples. The most frequent haplotype represented the coastal morph, also two haplotypes showing falcate dorsal fin, a characteristic describing the oceanic morph. This finding suggests that both morphs may exist in sympatry in Argentina. Furthermore, sampling was extended beyond the species’ previously known range, including individuals as far as seven hundred kilometers to the south. Therefore, new genetic data, despite being preliminary, hint at an unexpectedly higher genetic diversity of matrilines than previously anticipated.
The molecular characterization of anisotropic Herz-type Hardy spaces with two variable exponents
Authors: Guo Qingdong , Wang Wenhua 
Published: June 2020

Abstract
In this article, the authors establish the characterizations of a class of anisotropic Herz-type Hardy spaces with two variable exponents associated with a non-isotropic dilation on

ℝ

n

{{\mathbb{R}}}^{n}

in terms of molecular decompositions. Using the molecular decompositions, the authors obtain the boundedness of the central δ-Calderón-Zygmund operators on the anisotropic Herz-type Hardy space with two variable exponents.
Some aspects of human consent to sex with robots
Authors: Levy David 
Published: June 2020

AbstractPart of the ethical debate about sex with robots concerns whether sex with a robot is rape of that robot. It therefore makes sense for us to debate what should be the boundaries of consent, decades from now, i.e. consent given by humans to robots. How will the sexbot landscape look in situations when it is the human who is consenting, or not, to a sexual invitation or advance by the robot? The sexbot will have responsibilities towards its human partner, and there will be moral and legal consequences if it fails to deliver on those responsibilities. An unresolved ethical argument employed by many of those who deplore the coming advent of sex robots is that robots are unable to proffer a meaningful indication of sexual consent, and therefore a human deciding to have sex with a robot is committing rape of the robot. A parallel question, as yet to be addressed, is under what circumstances should a robot be considered to be acting in a sexually inappropriate or illegal manner towards a human? And this question embraces some others, including: “How can a robot determine, with any degree of certainty, whether or not a proximate human wants or at least consents to sex?”; “What behaviours by a robot are permissible within the #MeToo context when the robot is exploring a proximate human’s current level of sexual interest in the robot?”; and “If a robot oversteps the accepted bounds of sexual behaviour with a human, who is responsible and what should be the legal consequences?” We discuss these issues and speculate on how the sex robots of the future will be able to conform to the ethics of consent.
Recent advances in reactions promoted by amino acids and oligopeptides
Authors: Triandafillidi Ierasia , Voutyritsa Errika , Kokotos Christoforos G. 
Published: June 2020

Abstract
During the last 20 years, Organocatalysis has become one of the major fields of Catalysis. Herein, we provide a recent overview on reactions where the use of amino acids and peptides as the organocatalysts was employed. All aspects regarding aldol reactions, Michael reactions, epoxidation, Henry reactions and many others that are crucial for the reaction conditions and reaction mechanisms are discussed.