bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leading Transformation with Digital Innovations in Schools and Universities: Beyond Adoption
Authors: Kowch Eugene 
Published: January 2021

AbstractDigital innovations in schools and universities matter. New leadership approaches and new organization knowledge are necessary for leaders to realize long-term school and university transformations afforded by important digital innovation experiments. This chapter takes a hard look at leadership and organization theory and practice, along with a critical look at innovation adoption to help digital school and university innovation teams find more sustainable, impactful innovations. First, we examine research and theory on formal leadership and organization to argue that classical, formal leaders separate people from the work of others, limiting innovation teamwork. We also examine formal organizations as “houses,” finding that these over-structure people and power in vertical functional “boxes” in bureaucracies that limit school or university readiness to adapt—even when great digital innovations offer transformation potential. Less formal leadership and organization is then explored with evidence from the author’s research on leading complex adaptive teams as more adaptable organization network forms. We conclude that less formal leadership and less formal organizing structures offer more innovation potential by creating adaptive spaces for digital innovations. We present a new theory and guidelines for leading and participating in high-impact digital innovation networks working to lead learning organization emergence (transformation) via digital innovations.
Sounding the Alarm: The Council of Europe As the Guardian of the Rule of Law in Contemporary Europe
Authors: Polakiewicz Jörg , Kirchmayr Julia Katharina 
Published: January 2021

AbstractThe Council of Europe was founded upon the Rule of Law as one of its three core principles. This transpires from the preamble of the Council’s Statute and the requirements for membership, as enshrined in Article 3 where “every member of the Council of Europe must accept the principles of the Rule of Law [emphasis added] and of the enjoyment by all persons within its jurisdiction of human rights and fundamental freedoms, and collaborate sincerely and effectively in the realisation of the aim of the Council.”
A Potential Constitutional Moment for the European Rule of Law: The Importance of Red Lines
Authors: von Bogdandy Armin , Bogdanowicz Piotr , Canor Iris , Rugge Giacomo , Schmidt Matthias , Taborowski Maciej 
Published: January 2021

AbstractThis contribution deals with the current European rule of law crisis. It does so by analyzing the recent CJEU’s judgment in re LM and by considering its possible ramifications for the future of the rule of law in the EU. In particular, it is argued that, as a result of this judgment, the European rule of law as provided for by Art. 2 TEU has become a legally enforceable value. The CJEU has indeed made clear that this value features a set of minimum standards that the Member States cannot bluntly disregard. In the present context, which is characterized by the inaction of the supranational and national political institutions, a prominent role in safeguarding a liberal understanding of the European rule of law is played by the entire European judiciary (the so-called ‘Gerichtsverbund’), including national courts and tribunals.
Constitutional Crisis in Poland 2015–2016 in the Light of the Rule of Law Principle
Authors: Wiącek Marcin 
Published: January 2021

AbstractThis chapter concerns the constitutional crisis in Poland that began in 2015. It was triggered by appointing judges of the Constitutional Tribunal, by the outgoing Parliament, and then by re-appointing new judges for the same vacancies. Thus, the status of three judges elected by the previous Parliament and three judges elected by the current Parliament remains disputable.One of the crucial elements of the rule of law is the principle of legality. There are two aspects of this principle: the presumption of legality that covers all acts of state bodies; the revoking of this presumption may be performed only within procedures prescribed by the law. The law should indicate a state body competent to revoke the presumption of legality and define the legal effects of such revoking. If the law is incomplete, incoherent or imprecise in that scope—that may lead to legal and political crisis. Polish legislation and Constitution fail to comply with the said standard. This is one of the causes of the constitutional crisis in Poland.In a state governed by the rule of law state bodies should mutually respect their acts. State bodies should not treat acts or decisions issued by other state bodies as invalid or non-existent, unless it is declared within a procedure prescribed by the law. Otherwise, a legal chaos may occur. Courts are not empowered to evaluate the lawfulness of the Tribunal’s judgments. One of the crucial elements of the rule of law principle is the certainty of law.
Suspending Horizontal Solange: A Decentralized Instrument for Protecting Mutual Trust and the European Rule of Law
Authors: Canor Iris 
Published: January 2021

AbstractMutual trust is the basis on which the Member States’ judiciaries are expected to deal with each other in the European Union. By constitutionalizing the principle of mutual trust, the CJEU has introduced an axiological addition to the basic structure of the European Union. From a Union which concentrated on the vertical relationships between each Member State and the central Union’s institutions, the Union has turned out to be additionally preoccupied with the horizontal relationships among the Member States, which are based on what might be called a doctrine of Horizontal Solange.According to the principle of mutual trust, each Member State must presume that all other Member States are in compliance with EU law, in particular promote its values and respect European fundamental rights. This presumption, however, can be rebutted in exceptional circumstances. These exceptional circumstances are based on a two-prong test: first, the violation of the values or the fundamental rights must amount to a systemic deficiency; second, there is a need for an assessment whether the individual concerned will be the victim of this systemic deficiency.This contribution critically analyses these exceptional circumstances. Regarding the first prong, it is argued that the existence of systemic deficiencies should ideally be established by the CJEU via preliminary ruling references or via direct infringement proceedings. Alternatively, such systemic deficiencies may also be established by domestic courts in a host Member State. Regarding the second prong, it is argued that the individual test is redundant in cases where the systemic deficiency imposes challenges to the existing legal order of the Member State in question. Finally, it is argued that the suspension of mutual trust can serve as a decentralized instrument for protecting the European rule of law by pressuring the violating state to restore the rule of law.
Fever and Rheumatology
Authors: Cheikh Mohamed , Bahabri Nezar 
Published: January 2021

AbstractIn all the patients with rheumatic diseases, fever should prompt an immediate and thorough evaluation. There are different disorders that can cause fever and arthritis. Fever that is thought to be due to active rheumatic disease is seen in over 50% of patients with SLE30. However, it can be also related to or a sequel of an infectious process. There are many infectious diseases with rheumatological manifestations. The aim of this chapter therefore is to address variable relationships of fever with patients with arthritis. Fever of unknown origin will be addressed as some systemic rheumatic disease may present with fever. It is always a dilemma when an established patient with arthritis presents with fever. What should you do? This issue is addressed with a suggested diagnostic approach that guides you in a stepwise manner until you reach to the definitive diagnosis.
Gestational Rheumatology
Authors: Al-Osaimi Hanan , Althubiti Areej 
Published: January 2021

AbstractThere are changes that occur in the maternal organ systems due to increased demands of pregnancy. Most of the rheumatic disorders occur in the reproductive age group. The hormonal changes that occur during pregnancy may mimic the signs and symptoms of rheumatic disorders thereby making the diagnosis difficult. Rheumatological disorders need to be diagnosed and treated at least 6 months before the onset of pregnancy; otherwise they may have considerable effect on the prognosis of the disease. This is particularly evident in cases of SLE and anti-phospholipid antibody syndrome. Therefore, pregnancy is a crucial issue that needs to be clearly addressed in details in all female patients in the reproductive age group having some of the rheumatological disorders.
Eye and Rheumatology
Authors: Al-ghamdi Abdullah A 
Published: January 2021

AbstractThe ocular involvement in rheumatology can be in a wide variety; it ranges from simple episcleritis to significant visual loss. Early detection followed by appropriate management can reserve vision. Ophthalmic involvement may occur in all of the rheumatic disorders. Ocular manifestation may be a presenting sign in some disorders, as in juvenile idiopathic arthritis (JIA), ankylosing spondylitis (AS), and Sjogren’s syndrome (SjS), or can be a presenting sign with the systemic involvement as insystemic lupus erythematosus(SLE), polyarteritis nodosa (PAN), granulomatosis with polyangiitis (GPA), and systemic sclerosis. Thus ocular manifestations in rheumatologic diseases (Table 19.1) can be the link in approaching the diagnosis.
Diabetes and Rheumatology
Authors: Monjed Alaa 
Published: January 2021

AbstractDiabetes mellitus (DM) is a chronic disease characterized by persistent hyperglycaemia that happens as a result of a pancreatic insulin deficiency and/or insulin resistance. Its morbidity and mortality are primarily related to the resultant microvascular and macrovascular complications. Its prevalence has grown widely, which will result in higher rates of diabetic complications including rheumatic manifestations.
Towards Feynman rules for conformal blocks
Authors: Hoback Sarah , Parikh Sarthak 
Published: January 2021

Abstract
We conjecture a simple set of “Feynman rules” for constructing n-point global conformal blocks in any channel in d spacetime dimensions, for external and exchanged scalar operators for arbitrary n and d. The vertex factors are given in terms of Lauricella hypergeometric functions of one, two or three variables, and the Feynman rules furnish an explicit power-series expansion in powers of cross-ratios. These rules are conjectured based on previously known results in the literature, which include four-, five- and six-point examples as well as the n-point comb channel blocks. We prove these rules for all previously known cases, as well as two new ones: the seven-point block in a new topology, and all even-point blocks in the “OPE channel.” The proof relies on holographic methods, notably the Feynman rules for Mellin amplitudes of tree-level AdS diagrams in a scalar effective field theory, and is easily applicable to any particular choice of a conformal block beyond those considered in this paper.
Analyticity of off-shell Green’s functions in superstring field theory
Authors: Bhattacharya Ritabrata , Mahanta Ratul 
Published: January 2021

Abstract
We consider the off-shell momentum space Green’s functions in closed superstring field theory. Recently in [1], the off-shell Green’s functions — after explicitly removing contributions of massless states — have been shown to be analytic on a domain (to be called the LES domain) in complex external momenta variables. Analyticity of off-shell Green’s functions in local QFTs without massless states in the primitive domain is a well-known result. Using complex Lorentz transformations and Bochner’s theorem allow to extend the LES domain to a larger subset of the primitive domain. For the 2-, 3- and 4-point functions, the full primitive domain is recovered. For the 5-point function, we are not able to obtain the full primitive domain analytically, only a large part of it is recovered. While this problem arises also for higher-point functions, it is expected to be only a technical issue.
Non-minimal (self-)running inflation: metric vs. Palatini formulation
Authors: Racioppi Antonio 
Published: January 2021

Abstract
We consider a model of quartic inflation where the inflaton is coupled non-minimally to gravity and the self-induced radiative corrections to its effective potential are dominant. We perform a comparative analysis considering two different formulations of gravity, metric or Palatini, and two different choices for the renormalization scale, widely known as prescription I and II. Moreover we comment on the eventual compatibility of the results with the final data release of the Planck mission.
World-volume effective theories of locally non-geometric branes
Authors: Shiozawa Kenta , Sasaki Shin 
Published: January 2021

Abstract
We study world-volume effective theories of five-branes in type II string theories. We determine the bosonic zero-modes of the NS5-brane, the Kaluza-Klein monopole, the exotic Q5-, R5-branes and a space-filling brane, by direct calculations within the formalism of double field theory (DFT). We show that these zero-modes are Nambu-Goldstone modes associated with the spontaneously broken gauge symmetries in DFT. They are organized into the bosonic part of the six-dimensional $$ \mathcal{N} $$
N
= (1) vector and the $$ \mathcal{N} $$
N
= (2, 0) tensor multiplets. Among other things, we examine the locally non-geometric R5-branes and space-filling branes that are characterized by the winding space. We also study effective theories of five-branes with string worldsheet instanton corrections.
Giant gravitons in the Schrödinger holography
Authors: Georgiou George , Zoakos Dimitrios 
Published: January 2021

Abstract
We construct and study new giant graviton configurations in the framework of the non-supersymmetric Schrödinger holography. We confirm in the original Schrödinger spacetime, the picture discovered previously in the pp-wave limit of the geometry, namely that it is the giant graviton that becomes the energetically favored stable configuration compared to the point graviton one. Furthermore, there is a critical value of the deformation above which the point graviton disappears from the spectrum. The former fact leads also to the possibility of tunnelling from the point graviton to the giant graviton configuration. We calculate, explicitly, the instanton solution and its corresponding action which gives a measure of the tunnelling probability. Finally, we evaluate holographically the three-point correlation function of two giant gravitons and one dilaton mode as a function of the Schrödinger invariant.
Risk of UTI in kidney stone formers: a matched-cohort study over a median follow-up of 19 years
Authors: Brain Eleanor , Geraghty Robert M. , Cook Paul , Roderick Paul , Somani Bhaskar 
Published: January 2021

Abstract
Purpose
To describe risk of UTI in Stone formers comparing to non-stone formers.

Methods
Retrospective cohort study using electronic records for patients across southern England. Stone formers referred to a tertiary referral centre in Southern England, comparator patients were age and sex matched with 3:1 ratio from same database. Those with no documentation were excluded. UTI defined using ICD-10 codes. Risk of UTI presented as hazard ratio with 95% confidence interval, generated using cox regression. Sample size calculated using 80% power and significance set at 0.05.

Results
Eight hundred and nineteen stone formers were included after 1000 records were screened for inclusion, with 2477 age and sex matched non-stone formers extracted from the same database. Sample size was calculated at 287 per group. Stone formers were at significantly increased risk of developing a UTI (HR 5.67; 95% CI 4.52–7.18, p < 0.001). Median follow-up was 19 years (IQR: 15–22).

Conclusions
Kidney stone formers are at increased risk of developing urinary tract infections.
Atmospheric blocking events in the North Atlantic: trends and links to climate anomalies and teleconnections
Authors: Wazneh Hussein , Gachon Philippe , Laprise René , de Vernal Anne , Tremblay Bruno 
Published: January 2021

AbstractAtmospheric blockings are generally associated with large-scale high-pressure systems that interrupt west-to-east atmospheric flow in mid and high latitudes. Blockings cause several days of quasi-stationary weather conditions, and therefore can result in monthly or seasonal climate anomalies and extreme weather events on the affected regions. In this paper, the long-term coupled CERA-20C reanalysis data from 1901 to 2010 are used to evaluate the links between blocking events over the North Atlantic north of 35° N, and atmospheric and oceanic modes of climate variability on decadal time scales. This study indicates more frequent and longer lasting blocking events than previous studies using other reanalyses products. A strong relationship was found between North Atlantic blocking events and North Atlantic Oscillation (NAO), Atlantic Multidecadal Oscillation (AMO) and Baffin Island–West Atlantic (BWA) indices, in fall, winter and spring. More blocking events occur during the negative phases of the NAO index and positive phases of the BWA mode. In some situations, the BWA patterns provide clearer links with the North Atlantic blocking occurrence than with the NAO alone. The correlation between the synchronous occurrences of AMO and blocking is generally weak, although it does increase for a lag of about 6–10 years. Convergent cross mapping (CCM) furthermore demonstrates a significant two-way causal effect between blocking occurrences and the NAO and BWA indices. Finally, while we find no significant trends in blocking frequencies over the last 110 years in the Northern Hemisphere, these events become longer lasting in summer and fall, and more intense in spring in the North Atlantic.
Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study
Authors: Attems Johannes , Toledo Jon B. , Walker Lauren , Gelpi Ellen , Gentleman Steve , Halliday Glenda , Hortobagyi Tibor , Jellinger Kurt , Kovacs Gabor G. , Lee Edward B. , Love Seth , McAleese Kirsty E. , Nelson Peter T. , Neumann Manuela , Parkkinen Laura , Polvikoski Tuomo , Sikorska Beata , Smith Colin , Grinberg Lea Tenenholz , Thal Dietmar R. , Trojanowski John Q. , McKeith Ian G. 
Published: January 2021

AbstractCurrently, the neuropathological diagnosis of Lewy body disease (LBD) may be stated according to several staging systems, which include the Braak Lewy body stages (Braak), the consensus criteria by McKeith and colleagues (McKeith), the modified McKeith system by Leverenz and colleagues (Leverenz), and the Unified Staging System by Beach and colleagues (Beach). All of these systems use semi-quantitative scoring (4- or 5-tier scales) of Lewy pathology (LP; i.e., Lewy bodies and Lewy neurites) in defined cortical and subcortical areas. While these systems are widely used, some suffer from low inter-rater reliability and/or an inability to unequivocally classify all cases with LP. To address these limitations, we devised a new system, the LP consensus criteria (LPC), which is based on the McKeith system, but applies a dichotomous approach for the scoring of LP (i.e., “absent” vs. “present”) and includes amygdala-predominant and olfactory-only stages. α-Synuclein-stained slides from brainstem, limbic system, neocortex, and olfactory bulb from a total of 34 cases with LP provided by the Newcastle Brain Tissue Resource (NBTR) and the University of Pennsylvania brain bank (UPBB) were scanned and assessed by 16 raters, who provided diagnostic categories for each case according to Braak, McKeith, Leverenz, Beach, and LPC systems. In addition, using LP scores available from neuropathological reports of LP cases from UPBB (n = 202) and NBTR (n = 134), JT (UPBB) and JA (NBTR) assigned categories according to all staging systems to these cases. McKeith, Leverenz, and LPC systems reached good (Krippendorff’s α ≈ 0.6), while both Braak and Beach systems had lower (Krippendorff’s α ≈ 0.4) inter-rater reliability, respectively. Using the LPC system, all cases could be unequivocally classified by the majority of raters, which was also seen for 97.1% when the Beach system was used. However, a considerable proportion of cases could not be classified when using Leverenz (11.8%), McKeith (26.5%), or Braak (29.4%) systems. The category of neocortical LP according to the LPC system was associated with a 5.9 OR (p < 0.0001) of dementia in the 134 NBTR cases and a 3.14 OR (p = 0.0001) in the 202 UPBB cases. We established that the LPC system has good reproducibility and allows classification of all cases into distinct categories. We expect that it will be reliable and useful in routine diagnostic practice and, therefore, suggest that it should be the standard future approach for the basic post-mortem evaluation of LP.
Patient and family financial burden associated with cancer treatment in Canada: a national study
Authors: Longo Christopher J. , Fitch Margaret I. , Loree Jonathan M. , Carlson Linda E. , Turner Donna , Cheung Winson Y. , Gopaul Darin , Ellis Janet , Ringash Jolie , Mathews Maria , Wright Jim , Stevens Christiaan , D’Souza David , Urquhart Robin , Maity Tuhin , Balderrama Fanor , Haddad Evette 
Published: January 2021

Abstract
Goal
To determine patient-reported financial and family burden associated with treatment of cancer in the previous 28 days across Canada.

Methods
A self-administered questionnaire (P-SAFE v7.2.4) was completed by 901 patients with cancer from twenty cancer centres nationally (344 breast, 183 colorectal, 158 lung, 216 prostate) measuring direct and indirect costs related to cancer treatment and foregone care. Monthly self-reported out-of-pocket-costs (OOPCs) included drugs, homecare, homemaking, complementary/ alternative medicines, vitamins/supplements, family care, accommodations, devices, and “other” costs. Travel and parking costs were captured separately. Patients indicated if OOPC, travel, parking, and lost income were a financial burden.

Results
Mean 28-day OOPCs were CA$518 (US Purchase Price Parity [PPP] $416), plus CA$179 (US PPP $144) for travel and CA$84 (US PPP $67) for parking. Patients self-reporting high financial burden had total OOPCs (33%), of CA$961 (US PPP $772), while low-burden participants (66%) had OOPCs of CA$300 (US PPP $241). “Worst burden” respondents spent a mean of 50.7% of their monthly income on OOPCs (median 20.8%). Among the 29.4% who took time off work, patients averaged 18.0 days off. Among the 26.0% of patients whose caregivers took time off work, caregivers averaged 11.5 days off. Lastly, 41% of all patients had to reduce spending. Fifty-two per cent of those who reduced spending were families earning < CA$50,000/year.

Conclusions
In our Canadian sample, high levels of financial burden exist for 33% of patients, and the severity of burden is higher for those with lower household incomes.
Magnetic resonance imaging template to standardize reporting of anal fistulas
Authors: Sudoł-Szopińska I. , Santoro G. A. , Kołodziejczak M. , Wiaczek A. , Grossi U. 
Published: January 2021

AbstractAnal fistula (AF) is a common referral to colorectal surgeons. Management remains challenging and sometimes controversial. Magnetic resonance imaging (MRI) is commonly performed in initial workup for AF. However, reports often lack key information for guiding treatment strategies. It has been shown that with structured radiology reports, there is less missing information. We present a structured MRI template report including 8 key descriptors of anal fistulas, whose effectiveness and acceptability are being assessed in a cross-sectional study (NCT04541238).