bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bioimpedance Guided Fluid Management in Peritoneal Dialysis
Authors: Tian Na , Yang Xiao , Guo Qunying , Zhou Qian , Yi Chunyan , Lin Jianxiong , Cao Peiyi , Ye Hongjian , Chen Menghua , Yu Xueqing 
Published: April 2020

Background and objectives
Bioelectrical impedance analysis (BIA) devices can help assess volume overload in patients receiving maintenance peritoneal dialysis. However, the effects of BIA on the short-term hard end points of peritoneal dialysis lack consistency. This study aimed to test whether BIA-guided fluid management could improve short-term outcomes in patients on peritoneal dialysis.

Design, setting, participants, & measurements
A single-center, open-labeled, randomized, controlled trial was conducted. Patients on prevalent peritoneal dialysis with volume overload were recruited from July 1, 2013 to March 30, 2014 and followed for 1 year in the initial protocol. All participants with volume overload were 1:1 randomized to the BIA-guided arm (BIA and traditional clinical methods) and control arm (only traditional clinical methods). The primary end point was all-cause mortality and secondary end points were cardiovascular disease mortality and technique survival.

Results
A total of 240 patients (mean age, 49 years; men, 51%; diabetic, 21%, 120 per group) were enrolled. After 1-year follow-up, 11(5%) patients died (three in BIA versus eight in control) and 21 patients were permanently transferred to hemodialysis (eight in BIA versus 13 in control). The rate of extracellular water/total body water decline in the BIA group was significantly higher than that in the control group. The 1-year patient survival rates were 96% and 92% in BIA and control groups, respectively. No significant statistical differences were found between patients randomized to the BIA-guided or control arm in terms of patient survival, cardiovascular disease mortality, and technique survival (P>0.05).

Conclusions
Although BIA-guided fluid management improved the fluid overload status better than the traditional clinical method, no significant effect was found on 1-year patient survival and technique survival in patients on peritoneal dialysis.
Early Metabolic Features of Genetic Liability to Type 2 Diabetes: Cohort Study With Repeated Metabolomics Across Early Life
Authors: Bell Joshua A. , Bull Caroline J. , Gunter Marc J. , Carslake David , Mahajan Anubha , Davey Smith George , Timpson Nicholas J. , Vincent Emma E. 
Published: April 2020

OBJECTIVE
Type 2 diabetes develops for many years before diagnosis. We aimed to reveal early metabolic features characterizing liability to adult disease by examining genetic liability to adult type 2 diabetes in relation to metabolomic traits across early life.

RESEARCH DESIGN AND METHODS
Up to 4,761 offspring from the Avon Longitudinal Study of Parents and Children were studied. Linear models were used to examine effects of a genetic risk score (162 variants) for adult type 2 diabetes on 229 metabolomic traits (lipoprotein subclass–specific cholesterol and triglycerides, amino acids, glycoprotein acetyls, and others) measured at age 8 years, 16 years, 18 years, and 25 years. Two-sample Mendelian randomization (MR) was also conducted using genome-wide association study data on metabolomic traits in an independent sample of 24,925 adults.

RESULTS
At age 8 years, associations were most evident for type 2 diabetes liability (per SD higher) with lower lipids in HDL subtypes (e.g., −0.03 SD [95% CI −0.06, −0.003] for total lipids in very large HDL). At 16 years, associations were stronger with preglycemic traits, including citrate and with glycoprotein acetyls (0.05 SD; 95% CI 0.01, 0.08), and at 18 years, associations were stronger with branched-chain amino acids. At 25 years, associations had strengthened with VLDL lipids and remained consistent with previously altered traits, including HDL lipids. Two-sample MR estimates among adults indicated persistent patterns of effect of disease liability.

CONCLUSIONS
Our results support perturbed HDL lipid metabolism as one of the earliest features of type 2 diabetes liability, alongside higher branched-chain amino acid and inflammatory levels. Several features are apparent in childhood as early as age 8 years, decades before the clinical onset of disease.
Islam dalam Budaya Jawa Perspektif Al-Qurâ€™an
Authors: Umar Mohamad Toha 
Published: April 2020

The purpose of this study is to unfold the relations between culture and Islam in the Qurâ€™anic perspective. This paper examines the traditions that are absorbed into the aesthetic values of Islam, namely Sedekah Laut (sea offerings) and Wayang (shadow puppet). The data were collected through observations and library studies to find out the perspective of the Quran in viewing culture and tradition. The results of this study indicated that the Quran provides spaces for humans to constantly do ijtihad (seeking) that tradition and culture (â€˜urf) can be positioned as a source of Islamic law (fiqh). In the meantime, the rule of ushul fiqh for this case is â€œall cases are basically permitted until an argument comes to forbid them.â€ The results of this study showed that the Javanese traditions and culture, especially Sedekah Laut and Wayang, contained the values of Aqidah (faith), Muamalah (social values), and Akhlaqul Karimah (morals). In the Aqidah value, Wayang and Sedekah Laut are positioned as symbols of obedience and gratitude to Allah SWT. In the Muamalah value, tradition can evoke the strength of the community in various fields, for example, social and economy because both traditions, especially the sea offering are able to attract people. Meanwhile, the Akhlaqul Karimah value of the sea offering is that it represents the relationship between humans and nature, while the puppet is that it becomes disposition symbols aimed at Allah SWT.

Tujuan penelitian ini untuk mengungkap hubungan antara budaya dan Islam dalam perspektif al-Qurâ€™an. Tulisan ini mengkaji tradisi yang diserap ke dalam nilai estetika Islam, yakni sedekah laut dan wayang. Data dalam tulisan ini berdasarkan observasi dan data kepustakaan untuk mengetahui perspektif al-Qurâ€™an dalam memandang budaya dan tradisi. Hasil penelitian ini menunjukkan bahwa Al-Qurâ€™an memberikan ruang bagi manusia untuk senantiasa berijtihad bahwa tradisi dan budaya (â€™urf) dapat diposisikan sebagai sumber hukum (fiqh) Islam. Dalam pada itu, kaidah ushul fiqhnya adalah â€œpada mulanya semua perkara diperbolehkan, sebelum ada dalil yang mengharamkannya.â€ Hasil kajian ini menunjukkan bahwa dalam tradisi dan budaya (Jawa), khususnya wayang dan sedekah laut terdapat nilai aqidah, muamalah dan akhlaqul karimah. Dalam nilai aqidah, wayang dan sedekah laut diposisikan sebagai simbol ketaatan dan rasa syukur kepada Allah SWT. Dalam nilai muamalah, tradisi tersebut dapat membangkitkan kekuatan publik (kelompok) dalam berbagai bidang, misalnya sosial dan ekonomi karena kedua tradisi itu, khususnya sedekah laut mampu mengundang animo massa. Nilai akhlaqul karimah dalam sedekah laut merupakan representasi dari hubungan esoterik manusia dengan alam, sedangkan dalam wayang menjadi simbol perwatakan yang mengarah kepada Allah SWT.
HUBUNGAN ANTARA ETOS KERJA, PENGETAHUAN MANAJEMEN, DAN KINERJA PROFESIONAL GURU TEKNOLOGI DI SULAWESI UTARA
Authors: Waworuntu Jimmy 
Published: April 2020

AbstrakKarena mutu pendidikan di Indonesia nampak belum begitu baik, kinerja guru hendaknya di perbaiki. Dua variabel di teliti yakni etos kerja dan pengetahuan manajemen untuk melihat apakah variabel-variabel tersebut mempunyai hubungan positif dengan kinerja profesional guru. Penelitian ini sudah dilaksanakan pada guru-guru teknologi di beberapa sekolah menengah kejuruan di Sulawesi Utara, Indonesia. Ini merupakan suatu penelitian korelasional dengan 55 guru sebagai sampel yang diambil secara acak dan proporsional dari tiga sekolah menengah kejuruan yang mewakili. Tiga instrument penelitian digunakan untuk mengumpul data yaitu kinerja profesional dan etos kerja sebagai angket, dan pengetahuan manajemen sebagai test. Hasil penelitian menunjukan (1) ada hubungan positif antara etos kerja dan kinerja profesional, (2) ada hubungan positif antara pengetahuan manajemen dan kinerja profesional, dan (3) ada hubungan positif etos kerja dan pengetahuan manajemen secara bersama-sama dengan kinerja profesional. Hasil penelitian tersebut dapat menjadi informasi yang penting bagi kepala sekolah, dinas pendidikan dan pemerintah bahwa untuk meningkatkan kinerja profesional guru teknologi dapat dicapai melalui peningkatan etos kerja dan pengetahuan manajemen mereka. Dengan demikian mutu pendidikan juga dapat ditingkatkan.Kata kunci: Kinerja Profesional, Etos Kerja, Pengetahuan Manajemen, Guru Teknologi
An Overview of Novel Corona Virus 2019-nCoV and Their Clinical and Immune Responses
Authors: Sheetal Devi  , Manish Kumar  , Prabhat Kumar Upadhyay  , Anuj Malik  , Beena Kumari  , Raj Singh  , Anil Kumar  , Pandurangan A  
Published: April 2020

The novel virus such as corona virus 2019 is the main cause of the disease that is declared by the WHO (World Health Origination). Some other virus similar to this virus were also discovered in initial year of 21th century such as SARS-CoV in 2003, HCoV NL63 in 2004, HKU1 in 2005, MERS-CoV in 2012, and SARS-CoV-2 in 2019. The first few cases of covid-19 were detected from direct contact to the infected animal to human which is also called as animal to human transmission. Due to direct exposure of this virus to infected animals the human to human transmission of the virus is as well possible, which is also likely to be consider and measured as core form of transmission. According to the reports of WHO by 26 February 2020, patients suffering from COVID-19 reduced gradually in China but rapidly increased in countries like Italy, Iran and South Korea. The infection caused by the COVID 19 is detected by looking at the symptoms and it ultimately confirmed by the reverse transcription polymerase chain reaction (rRT-PCR) of infected secretions with 71% sensitivity and computed tomography scan with 98%. The antimalarial medicate, hydroxychloroquine, is authorized for the chemoprophylaxis and treatment of intestinal sickness and as a disease changing antirheumatic drugs. Pharmacological demonstrating dependent on observed drug absorptions and in vitro drug testing propose that prophylaxis with hydroxychloroquine at affirmed portions could anticipate SARS-CoV-2 contamination and improve viral shedding. Clinical preliminaries of hydroxychloroquine treatment for COVID-19 pneumonia are in progress in China (NCT04261517 and NCT04307693).
¿Quién soy yo? Reflexiones teórico sistémicas acerca de la indentidad individual
Authors: Morales Francisco Xavier 
Published: April 2020

The problem of identity is an issue of contemporary society that is not only expressed in daily life concerns but also in discourses of politics and social movements. Nevertheless, the I and the needs of self-fulfillment usually are taken for granted. This paper offers thoughts regarding individual identity based on Niklas Luhmann’s systems theory. From this perspective, identity is not observed as a thing or as a subject, but rather as a “selfillusion” of a system of consciousness, which differentiates itself from the world, event after event, in a contingent way. As concerns the definition of contents of self-identity, the structures of social systems define who is a person, how he or she should act, and how much esteem he or she should receive. These structures are adopted by consciousness as its own identity structures; however, some social contexts are more relevant for self-identity construction than others. Moral communication increases the probability that structure appropriation takes place, since the emotional element of identity is linked to the esteem/misesteem received by the individual from the interactions in which he or she participates.
Debatir el populismo: Lógicas, afectos y ciclos de conflictividad.
Authors: Raza Sebastián , Vasquez Jorge Daniel 
Published: April 2020

En lo que sigue, trazaremos tres distinciones con el objetivo de poner en diálogo las contribuciones y descubrir lo que consideramos como coordenadas elementales para una discusión acerca del populismo a partir de las contribuciones presentes en este dossier. En un primer momento, mediante la distinción entre acercamientos que buscan atrapar una lógica del populismo y aquellos que buscan explicarlos en su dimensión histórico-concreta, pondremos en diálogo a nuestras contribuciones al tiempo que buscaremos resaltar puntos de debate importantes, como el del lugar de los afectos en la política populista. En un segundo momento, nos guiará la distinción entre populismo como fenómeno anti-institucional y populismo como momento instituyente para enmarcar nuestras contribuciones, y resaltar ciertos puntos de encuentro y desencuentro entre las distintas contribuciones. Por último, trataremos acerca de la globalidad del populismo como fenómeno y como categoría, en contraste con su regionalidad en tanto experiencia política. Al final de esta introducción, esperamos poner en evidencia las coordenadas que pueden guiar debates sobre populismo, así como la interrelación entre las distinciones realizadas. De igual manera, se evidenciará y enmarcará la discusión del populismo como tema global con matices particulares y regionales.
Upaya Cegah Premarital Seks dengan Pemberdayaan Teman Sebaya
Authors: Izah Nilatul , Hidayah Seventina Nurul , Rakmita Rakmita , Aldina Himdya 
Published: April 2020

Hasil zero survey yang dilakukan diseluruh wilayah Kabupaten Tegal sejak 1996-2006 menunjukkan 27 orang mengdap HIV positif dan klinik VCT mencatat lima orang terinfeksi. Kalisapu merupakan salahsatu Desa di yang terletak di Kabupaten Tegal Kecamatan Slawi. Pendidikan di Desa Kalisapu terbilang masih kurang meskipun di daerah sekitar terdapat perguruan tinggi, hal tersebut terjadi karena banyaknya perempuan yang bekerja dan memaksa anaknya untuk bekerja setelah lulus SMP atau SMA. Terdapat pabrik teh yang dekat dengan Desa Kalisapu menyebabkan para remaja memilih bekerja daripada meneruskan pendidikan. Kesibukan bekerja membuat para remaja mendapatkan informasi kesehatan yang sangat minim terutama tentang kesehatan reproduksi. Berdasarkan studi pendahuluan terdapat beberapa remaja yang terpaksa menikah dalam usia muda (<20 tahun) dikarenakan telah hamil. Melihat fenomea yang ada penting sekali dilakukan pendidikan kesehatan kesehatan reproduksi khusunya bagi para remaja di Desa Kalisapu. Metode yang digunakan adalah pemberian penyuluhan dengan diskusi dan membentuk kader teman sebaya untuk kesehatan reproduksi pada remaja. Kegiatan Pengabdian dilaksanakan selama 2 hari pada tanggal 31 Juli dan 1 Agustus 2019 dengan jumlah peserta sebanyak 10 remaja yang terdiri dari remaja putra dan remaja putri yang bergabung dalam remaja Majlis Taklim Nurus Saadah. Kegiatan ini diawali dengan menilai sejauh mana pengetahuan remaja tentang esehatan reproduksi khusunya pada remaja, bagaimana upaya –upaya yang seharusnya dilakukan oleh remaja guna mencegah terjadinya pre marital seks pada remaja. Penilaian pengetahuan yang dilakukan yaitu melalui pertanyaan – pertanyaan yang diajukan tim sebelum melakukan sosialisasi, setelah mengetahui sejauhmana pengetahuan remaja tentang kesehatan reproduksi pada remaja selanjutnya dilakukan kegiatan pemberian materi tentang kesehatan reproduksi serta upaya yang dapat mereka lakukan sebagai teman sebaya yang harus memberikan informasi tentang kespro remaja pada teman – teman mereka agar terjadinya pre marital seks dapat terhindari dengan diskusi. Setelah para remaja mengatakan mengerti dan sudah tidak ada diskusi selanjutnya tim melakukan evaluasi tentang kesehatan reproduksi remaja pada peserta. Hasil pengabdian yang telah dilaksanakan dapat disimpulkan remaja yang menjadi peserta pengabdian masyarakat mengalami peningkatan pengetahuan khususnya pegetahuan tentang kesehatan reproduksi remaja dalam upaya mencegah pre marital seks.
A Community Empowerment Model through Pesantren-Based Family Empowerment Post (POSDAYA)
Authors: Meiriki Andri , Rahayu Ety , Resnawaty Risna 
Published: April 2020

Purpose: This paper aims to analyze A Community Empowerment Model through Pesantren-based Family Empowerment Post (Posdaya).
Design/methodology/approach: The method used is composes a reality to be a story, describing a problem, event, phenomenon orderly, followed by analysis and interpretation to analyze the data in a perfect sequence.
Findings: 3 hypotheses are rejected while the other 3 is accepted.
Research limitations/implications: These components were: 1) Data collection; this was done through interviews. Besides, the data were also collected through a literature study. 2) Data Reduction, after the data were gathered, the researcher focused on removing unnecessary data and arrange the data to gain a conclusion. 3) Data display, this was done through sentences and structured story. 4) Conclusion drawing, this was done to gain full meaning from the processed data, creating a clear, complete synopsis.
Practical implications: Results show that from the 3 hypotheses proposed accepted, 1) Pesantren-based Posdaya needs to improve its resources through training or organizational education in order to improve the quality of empowerment program and the continuity of Posdaya activities. 2) Pesantren-based Posdaya needs to strengthen its social capital by establishing stronger social relationships with stakeholders, thus opening accessibility for community empowerment, or family empowerment in particular. 3) Pesantren-based Posdaya should strengthen its organizational structure and workgroup as the program implementer, and continuously monitor the program.
Originality/value: This paper is original.
Pemenuhan Hak Bekerja bagi Penyandang Disabilitas Fisik di Kota Batam
Authors: Tan Winsherly , Ramadhani Dyah Putri 
Published: April 2020

Negara Indonesia merupakan negara yang menjunjung tinggi hak asasi manusia. Perlindungan terhadap hak asasi manusia merupakan sebuah kewajiban bagi Pemerintah Indonesia. Perlindungan tersebut diberikan juga kepada penyandang disabilitas fisik. Indonesia telah memiliki seperangkat hukum yang memberikan perlindungan mengenai hak bekerja bagi penyandang disabilitas namun pada kenyataannya, Indonesia masih menghadapi problematika dalam pemenuhan hak tersebut termasuk pemerintah Kota Batam menghadapi problematika dalam memenuhi hak bekerja bagi penyandang disabilitas. Tujuan dari penelitian ini adalah untuk mengetahui pemenuhan hak bekerja bagi penyandang disabilitas dan tantangan yang mereka hadapi. Metode penelitian yang digunakan adalah pendekatan sosiologis yuridis. Teknik penelitian yang dilakukan adalah wawancara. Teori hukum yang digunakan dalam menganalisis penelitian ini adalah Teori Efektivitas Hukum oleh Soejono Soekanto dan Teori Keadilan Hukum oleh Jhon Rawls. Hasil penelitian menyatakan bahwa pemenuhan hak bekerja bagi penyandang disabilitas fisik di Kota Batam belum efektif dengan beberapa tantangan yaitu lemahnya peraturan di daerah Kota Batam dan lemahnya kemampuan yang mereka miliki.
Microstructure and Mechanical Properties of Al-Mg-Sc-Zr Alloy Modified by Friction-Stir Processing
Authors: Li M. , Zhou S. , Wang W. , Liu F. , Li H. , Qin Y. , Zhang Z. , Wu Y. 
Published: April 2020

Abstract
In this work, the effect of friction stir processing (FSP) on microstructure and mechanical properties of an Al-5Mg-0.2Sc-0.1Zr alloy was investigated in detail. The results showed that the as-cast alloy exhibited equiaxed grain structure with a large number of primary Al3(Sc,Zr) particles inside. FSP imposed a significant grain-refining effect on the alloy, changing the average grain size of 50.5 μm to 2.4 μm, which is attributed to the occurrence of dynamic recrystallization and generation of nanoscaled Al3(Sc,Zr) precipitates. These Al3(Sc,Zr) dispersoids intense impeded the movement of dislocation and grain boundaries and hindered the growth of recrystallized grains, resulting in a remarkable grain-refining strengthening, substructure strengthening and precipitation strengthening effect. On the other hand, the residual primary Al3(Sc,Zr) particles gave rise to a loss in ductility.
Examining the Expression of miR-205 and CEA mRNA in Peripheral Blood of Patients with OSCC(Oral Squamous Cell Carcinomas) and Comparing them with Healthy People
Authors: Nazarian Ameneh , Mohamadnia Abdolreza , Danaee Elham , Bahrami Naghmeh 
Published: April 2020

Introduction: Cancer is one of the most important causes of mortality in the world. So, in this study the changes of expressing miR-205 and CEA in oral cancer in peripheral blood were examined for early detection and better treatment.
Methods: In this study, we selected the number of 30 patient people and 30 healthy people. We measured their blood miR-205 and CEA using Real-Time PCR technique and evaluated the relationship between the expression of these biomarkers with tumor staging and cancer progression.
Findings: there is no a significant difference in mean age by comparing these two groups using t-test. The CEA mRNA biomarker was positive in 24 out of 30 people of the patient people group and was positive in 4 out of 30 people of the healthy people group. Statistical comparison represented a statistically significant difference between the two groups (P-value <0.001). The miR-205 biomarker was positive in 9 out of 30 people of the patient people group and was positive in 22 out of 30 people of the healthy people group. Statistical comparison represented a statistically significant difference the two groups (P-value <0.001).
Conclusion: In general, the research result can be considered as a screening test for early detection of the disease in the early stages. It is recommended to conduct more extensive studies with larger sample sizes to further proof of the research results.
Larangan Pemberian Dot/Kempeng dan Makanan/Minuman selain ASI dengan Cakupan ASI Eksklusif di Kabupaten Pangkep
Authors: Nasriani Nasriani 
Published: April 2020

Sehubungan dengan Sustainable Development Goals (SDGs) atau Tujuan Pembangunan Berkelanjutan 2030, menyusui merupakan salah satu langkah pertama bagi seorang manusia untuk mendapatkan kehidupan yang sehat dan sejahtera. Sayangnya, tidak semua orang mengetahui hal ini.PemerintahIndonesiatelah melakukanupaya peningkatanpemberianASI eksklusif dengan berbagaicara.Menerbitkanperaturan dan perundang- undangan mengenai pemberian ASI eksklusif pun sudah dilakukan, namun pelaksanaannya belum sesuai dengan Standar nasional Indonesia (SNI).Rendahnya cakupan pemberian ASI eksklusif ini dapat berdampak pada kualitas hidup generasi penerus bangsa dan juga pada perekonomian nasional. Penelitian ini bertujuan untuk menganalisa hubungan larangan pemberian dot/kempeng dan larangan pemberian makanan/minuman selain ASI Dengan Cakupan ASI Eksklusif Di Kabupaten Pangkep. Penelitian ini adalah observasional analitik dengan rancangn cross sectional study. Populasi dalam penelitian ini adalah kepala puskesmas /penanggung jawab program dan ibu post partum yang berada di seluruh puskemas Kabupaten Pangkep yaitu sebanyak 23 puskesmas. Penarikan sampel dari populasi penelitian dilakukan dengan carapurposive sampling yaitu puskesmas yang memiliki rawat inap di kabupaten pangkep sebanyak 22 puskesmas. Pengumpulan data dilakukan dengan cara melihat laporan ASI Eksklusif Dinas Kesehatan kabupaten Pangkep, pembagian kuesioner, wawancara kemudian diolah dengan menggunakan program SPSS dengan uji chi square. Teknik analisa data dengan menggunakan uji univariat, bivariat dan multivariate dengan metode forward stepwice (conditional). Menunjukkan bahwa p=1,000 (p>0,05)yang berarti H0 diterima. Dengan demikian tidak ada hubungan larangan pemberian dot/kempeng dan larangan pemberian makanan/minuman selain ASI berhubungan dengan cakupan ASi eksklusif. Pemberian informasi serta edukasi kepada Ibu-Ibu menyusui tentang pentingnya pemberian ASI dan dampak negatif dari penggunaan dot/kempeng.