bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expectativas e sentimentos de familiares cuidadores de crianças com necessidades especiais que realizam equoterapia
Authors: Pereira Luiza Tarsilado Vale , Pereira Charlene De Oliveira , Maia Paula Christianne Gomes Gouveia Souto , De Sousa Milena Nunes Alves 
Published: November 2019

<p><strong>Objetivo</strong>: avaliar as expectativas e sentimentos de familiares cuidadores de crianças com necessidades especiais que realizam equoterapia. <strong>Metodologia</strong>: pesquisa de campo, com caráter descritivo e com abordagem quantitativa. O estudo aconteceu na cidade de Patos, localizada no sertão da Paraíba, com 18 familiares cuidadores (94,74%) de crianças assíduas às atividades do<br />Centro de Equoterapia. O instrumento utilizado para a coleta de dados validado em português foi o “Questionário para a Família” e duas questões adicionais elaboradas pela pesquisadora. Os dados foram analisados a partir da estatística descritiva. <strong>Resultados</strong>: o convívio com crianças portadoras de necesidade especiais gera expectativas quanto ao bem-estar dos filhos (88,9%), sucesso na<br />escola (50,0%), autonomia na vida diária (72,2%), felicidade (66,7%), normalidade (66,7%), cuidados pessoais (50,0%). Quanto aos sentimentos, destacou-se a ansiedade (44,4%), sentido de proteção (55,6%) e tristeza (67%). <strong>Conclusão</strong>: cuidar de crianças portadoras de necessidades especiais gera nos cuidadores uma série de sentimentos e expectativas, sendo estes causados por dilemas e dúvidas em relação à vida e ao futuro da criança.</p>
Avaliação de potenciais interações medicamentosas em pacientes da unidade de terapia intensiva de um hospital universitário
Authors: Gomes Alice Madilza Palmeira , Dias Bezerra Karoline Gomes , Oliveira Fernando De Sousa 
Published: November 2019

<p><strong>Introdução:</strong> entende-se por interação medicamentosa a ação de um medicamento, alimento ou qualquer substância química sobre o efeito de outro medicamento gerando uma resposta farmacológica ou clínica. Associações de fármacos no tratamento de doenças crônicas são muito comuns, principalmente em pacientes de unidade de terapia intensiva, no entanto, podem causar algumas interações medicamentosas, as quais podem ser responsáveis por insucesso terapêutico e aumento dos custos hospitalares. <strong>Objetivo:</strong> analisar a ocorrência e o perfil de potenciais interações medicamentosas em pacientes da UTI do Hospital Universitário Alcides Carneiro em Campina Grande-PB. <strong>Metodologia:</strong> realizou-se um estudo transversal descritivo, com abordagem quantitativa e qualitativa, a partir de dados coletados de prescrições da UTI entre janeiro a junho de 2017, utilizando de um formulário específico. Para identificação das potenciais interações utilizou-se o <em>Drug-Reax System do software Micromedex<sup>®</sup> Health Series</em>. <strong>Resultados: d</strong>entre as 109 prescrições avaliadas, 69,7% apresentaram alguma interação, totalizando 244 potenciais interações. Foram detectados em média 6,9 medicamentos/prescrição. A maioria das interações apresentou mecanismo de ação farmacodinâmico, grau de severidade maior, razoável documentação e início de ação não especificado. Todas as prescrições com mais de 10 fármacos apresentaram algum tipo de interação. <strong>Conclusão:</strong> o surgimento de interações em UTI possui alta prevalência, mas as associações são justificadas pelo seu risco/benefício, por isso devem ser avaliadas e monitoradas pelo farmacêutico e a equipe de saúde, com intuito de reduzir o surgimento de potenciais interações que levem a falhas terapêuticas e risco ao paciente, aperfeiçoando assim o manejo clínico.</p>
Lipoma em região pterigomandibular. Relato de caso
Authors: Rocha de Souza Kelvin Borges , Silva Railla Souza , Teixeira de Carvalho Marister Ribeiro , Peixoto Medrado Alena Ribeiro , Costa Freire Tila Fortuna 
Published: November 2019

<p>O lipoma é um tumor benigno de crescimento lento, assintomático, com consistência amolecida. Clinicamente, apresenta-se como massa nodular, pedunculada ou séssil, de aspecto gelatinoso com superfície lisa recoberta por mucosa bucal saudável. Apesar de comum em outras partes do corpo, esse tumor raramente acomete a cavidade bucal. Seu tratamento consiste na excisão cirúrgica, e apresenta raras recidivas, devido à presença de uma pseudocápsula que separa a lesão dos tecidos circunvizinhos. <strong>Objetivo</strong>: este trabalho objetiva relatar o caso clínico de um paciente com lipoma em região peterigomandibular, tratado com sucesso por excisão irúrgica. <strong>Relato de caso</strong>: paciente masculino, de 51 anos, relatou aparecimento de aumento de volume assintomático em região posterior da cavidade bucal, com evolução de aproximadamente 8 meses. Foi realizada biópsia excisional da lesão sob anestesia local, sem complicações. A suspeita diagnóstica de lipoma foi confirmada por meio de laudo histopatológico. Paciente encontra-se no vigésimo mês de pós-operatório, sem recidiva da lesão. <strong>Conclusão</strong>: por ser raro na região maxilofacial, o tumor, quando acomete<br />a mucosa bucal, deve ser relatado na literatura. No caso descrito, a biópsia excisional, realizada em âmbito ambulatorial, mostrou-se eficaz no tratamento do lipoma em região peterigomandibular.</p>
Endogenous beta‐galactosidase activity marks a TREM2‐expressing Kupffer cell population in injured livers of Lgr5‐LacZ and wild‐type mice
Authors: Klaas Mariliis , Mäemets‐Allas Kristina , Lõhmussaar Kadi , Tooming Mikk , Viil Janeli , Jaks Viljar 
Published: November 2019

Lgr5‐LacZ mice harbor the Escherichia coli LacZ gene encoding β‐galactosidase (β‐gal) under the control of the Lgr5 promoter, a stem/progenitor cell marker. In injured livers of Lgr5‐LacZ mice, cells expressing β‐galactosidase (β‐gal) are considered as potential bipotent liver progenitors; however, their origin and identity remain unknown. Unexpectedly, using lineage tracing, we demonstrate that the β‐gal+ cells do not originate from liver parenchymal cells. Instead, β‐gal+ cells, isolated from injured livers of both Lgr5‐LacZ and wild‐type mice, are positive for markers of Kupffer cells, liver‐resident macrophages. The β‐gal expression in these cells is a result of elevated expression of the endogenous beta‐galactosidase Glb1. In injured livers of Lgr5‐LacZ mice, bacterial β‐gal expression is very low, suggesting transgene silencing. The gene expression profile of the β‐gal+ Kupffer cells from injured livers suggests a role in liver regeneration.
Electrochromic Infrared Light Modulation in Optical Waveguides
Authors: Kim Jin Tae , Song Juhee , Ryu Hojun , Ah Chil Seong 
Published: November 2019

AbstractElectrochromic materials and devices have attracted much attention with their ability to tune the transmissions of visible to infrared (IR) light, allowing the creation of smart windows. This study presents a novel electrochromic device (ECD)‐based photonic device that can modulate IR light intensity in a planar optical waveguide ECD. To configure it, a multilayer ECD made of WO3 is integrated on a polymer optical waveguide platform. By using the waveguide to change the optical properties of the ECD electrically, IR light propagating along the optical waveguide core undergoes electroabsorption loss due to the change in charge carrier density in WO3 layer and its intensity is modulated with an extinction depth of 0.6 dB mm−1. Experimental results show that the device is capable of discrete intensity attenuation by applying a distinct level gate voltage. Periodic application of gate voltage leads the device to serve as an optical modulator on the order of subseconds. The results also confirm that a new approach to consider ECD‐based optical modulators can pave the way for the development of planar photonic‐integrated circuits and systems.
Liver stiffness‐spleen size‐platelet ratio as a useful clinical predictor for esophageal varices bleeding in patients with viral cirrhosis
Authors: Yan Sheng‐Lei , Chen Chien‐Hua , Yeh Yung‐Hsiang 
Published: November 2019

AbstractThe aim of this study was to determine the diagnostic accuracy of liver stiffness measurement‐spleen size‐to‐platelet ratio score (LSPS) and clinical factors for predicting high‐risk esophageal varices (HREV) in patients with viral cirrhosis. From January 2016 to November 2017, cirrhotic patients with either chronic hepatitis B or hepatitis C were consecutively included in this study. All included patients underwent liver stiffness measurement (LSM) and esophagogastroduodenoscopy examinations during the study period. LSM was performed using transient elastography with FibroScan. HREV were defined as medium‐to‐large esophageal varices (EV) and small EV with red color signs, while low‐risk EV (LREV) as small EV without red color signs. A total of 151 patients with either HBV‐ or HCV‐related cirrhosis were included in this study. Multivariate analysis and stepwise logistic regression analysis showed that LSPS (P < .0001; odds ratio 12.4; 95% confidence interval (CI), 5.04‐30.62), platelet count/spleen size ratio (P < .0001; odds ratio 12.2; 95% CI, 5.10‐29.04), and albumin level (P < .0001; odds ratio 5.5; 95% CI, 2.52‐12.07) were confirmed as independent predictors of HREV. The values of area under the receiver‐operating characteristic (AUROC) curves were 0.82 (95% CI, 0.75‐0.89) for LSPS, 0.80 (95% CI, 0.72‐0.87) for platelet count/spleen size ratio, and 0.75 (95% CI, 0.67‐0.83) for albumin level. Receiver‐operating characteristic curve analysis and diagnostic performance showed that LSPS was superior over other noninvasive tests in terms of AUROC. At the optimal cutoff value of 2.3 for LSPS, the values of AUROC, sensitivity, specificity, negative predictive value, positive predictive value, and accuracy were 0.82 (95% CI, 0.75‐0.89), 85.4% (95% CI, 72.2%‐93.9%), 68.0% (95% CI, 58.0%‐76.8%), 90.9% (95% CI, 83.3%‐95.3%), 55.4% (95% CI, 47.8%‐62.8%), and 73.5% (95% CI, 65.7%‐80.4%), respectively. However, there were no significant differences between the values of AUROC for LSPS and other noninvasive tests (P > .05, DeLong test). The results of our study showed that LSPS provided good diagnostic accuracy for detecting HREV in patients with viral cirrhosis.
Electrospinning of polyacrylonitrile nanofibers embedded with zerovalent iron and cerium oxide nanoparticles, as Cr(VI) adsorbents for water treatment
Authors: Vazquez‐Velez E. , Lopez‐Zarate L. , Martinez‐Valencia H. 
Published: November 2019

ABSTRACTZerovalent iron (ZVI) and cerium oxide (CeO2) nanoparticles (NPs) embedded in polyacrylonitrile nanofibers (NFs) were obtained via electrospinning. Each NF was characterized using Fourier transform infrared spectroscopy and X‐ray diffraction. The scaffold morphology and average diameter of the NFs were determined using scanning electron microscopy (SEM). Energy dispersive X‐ray spectroscopy (EDS) mapping and Raman spectroscopy were used to characterize the NPs dispersion in the NFs. The Cr(VI) removal efficiency (%E) of ZVI and CeO2 NPs was compared with the efficiency of their corresponding NFs. CeO2 NPs showed 79% Cr(VI) removal; the efficiency was better for their NFs (96%). Regeneration of ZVI NFs was 98 %E. ZVI NPs were the best adsorbent with 99.9% efficiency. An adsorption mechanism was proposed using Langmuir, Freundlich, and Temkin isotherm models. SEM–EDS analyses revealed that Cr adsorbed on the NP and NF surfaces. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 137, 48663.
Properties of tire tread compounds based on functionalized styrene butadiene rubber and functionalized natural rubber
Authors: Sirisinha Chakrit , Sae‐oui Pongdhorn , Suchiva Krisda , Thaptong Puchong 
Published: November 2019

ABSTRACTTire tread compounds based on various rubber types, that is, solution styrene‐butadiene rubber (SSBR), functionalized (propylamine and dimethoxysilane) solution styrene‐butadiene rubber (F‐SSBR), natural rubber (NR), chloroacetate‐modified natural rubber (CNR), and their blends, were prepared and used as raw rubbers. Properties of tire tread compounds and tire performance were then investigated. Due to the presence of chloroacetate group on its mainchains, CNR demonstrates increases in glass transition temperature and rubber‐filler interaction compared to NR leading to a significant improvement in tire performance, particularly wet grip (WG; ~88%), fuel‐saving efficiency (FSE; ~15%), and abrasion resistance (~11%). Similarly, F‐SSBR shows a greater tire performance than SSBR (~20, ~13, and ~7% improvements in WG, FSE, and abrasion resistance, respectively). Among the rubber blends, F‐SSBR/CNR gives the highest tire performance, followed by F‐SSBR/NR, SSBR/CNR, and SSBR/NR, respectively. The results suggest the significant enhancement in properties of tire tread compounds by the presence of active functional groups in NR and SSBR molecules. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 137, 48696.
The genome of Chenopodium pallidicaule: An emerging Andean super grain
Authors: Mangelson Hayley , Jarvis David E. , Mollinedo Patricia , Rollano‐Penaloza Oscar M. , Palma‐Encinas Valeria D. , Gomez‐Pando Luz Rayda , Jellen Eric N. , Maughan Peter J. 
Published: November 2019

PremiseCañahua is a semi‐domesticated crop grown in high‐altitude regions of the Andes. It is an A‐genome diploid (2n = 2x = 18) relative of the allotetraploid (AABB) Chenopodium quinoa and shares many of its nutritional benefits. Cañahua seed contains a complete protein, a low glycemic index, and offers a wide variety of nutritionally important vitamins and minerals.MethodsThe reference assembly was developed using a combination of short‐ and long‐read sequencing techniques, including multiple rounds of Hi‐C–based proximity‐guided assembly.ResultsThe final assembly of the ~363‐Mbp genome consists of 4633 scaffolds, with 96.6% of the assembly contained in nine scaffolds representing the nine haploid chromosomes of the species. Repetitive element analysis classified 52.3% of the assembly as repetitive, with the most common repeat identified as long terminal repeat retrotransposons. MAKER annotation of the final assembly yielded 22,832 putative gene models.DiscussionWhen compared with quinoa, strong patterns of synteny support the hypothesis that cañahua is a close A‐genome diploid relative, and thus potentially a simplified model diploid species for genetic analysis and improvement of quinoa. Resequencing and phylogenetic analysis of a diversity panel of cañahua accessions suggests that coordinated efforts are needed to enhance genetic diversity conservation within ex situ germplasm collections.
Characterization of microsatellite loci in Brighamia insignis and transferability to other genera in the Hawai‘ian lobelioid group
Authors: Fant Jeremie B. , Fluckes Mereida , James Evana , Noble Hilary , Wood Jordan 
Published: November 2019

PremiseMicrosatellite markers were developed to measure genetic diversity and relatedness of ex situ collections of Brighamia insignis (Campanulaceae).Methods and ResultsPotential microsatellite markers were identified from two sources; 28 were developed for B. insignis and an additional 12 markers from a previously published study of Lobelia villosa. Primer pairs were tested on 30 individuals of B. insignis and 24 individuals of B. rockii to provide measures of genetic diversity and inbreeding. We assessed cross‐species amplification in an additional 13 taxa that represented all six genera within the Hawai‘ian lobelioid group to determine the broader applicability of the markers.ConclusionsResults indicate that these primers will provide useful estimates of genetic diversity and relatedness of ex situ collections of both Brighamia species. In addition, we have also demonstrated the widespread applicability of these markers for use in population genetic studies of several species within the Hawai‘ian lobelioid group.
How online word‐of‐mouth impacts receivers
Authors: Moore Sarah G. , Lafreniere Katherine C. 
Published: November 2019

AbstractOnline word‐of‐mouth (WOM) can impact consumers’ product evaluations, purchase intentions, and choices—but when does it do so? How do those receiving WOM know whether to rely on a particular message? This article suggests that the multiple players involved in online WOM (receivers, senders, sellers, platforms, and other consumers) each have their own interests, which are often in conflict. Thus, receivers of WOM are faced with a judgment task in deciding what information to rely on: They must make inferences about the product in question and about the players who provide or present WOM. To do so, they use signals embedded in various components of WOM, such as average star ratings, message content, or sender characteristics. The product and player information provided by these signals shapes the impact of WOM by allowing receivers to make inferences about (a) their likelihood of product satisfaction, and (b) the trustworthiness of WOM players, and therefore the trustworthiness of their content. This article summarizes how each player changes the impact of online WOM, providing a lens for understanding the current literature in online WOM, offering insights for theory in this context, and opening up pathways for future research.
Nucleic Acid Catalysis under Potential Prebiotic Conditions
Authors: Le Vay Kristian , Salibi Elia , Song Emilie Y. , Mutschler Hannes 
Published: November 2019

AbstractCatalysis by nucleic acids is indispensable for extant cellular life, and it is widely accepted that nucleic acid enzymes were crucial for the emergence of primitive life 3.5‐4 billion years ago. However, geochemical conditions on early Earth must have differed greatly from the constant internal milieus of today's cells. In order to explore plausible scenarios for early molecular evolution, it is therefore essential to understand how different physicochemical parameters, such as temperature, pH, and ionic composition, influence nucleic acid catalysis and to explore to what extent nucleic acid enzymes can adapt to non‐physiological conditions. In this article, we give an overview of the research on catalysis of nucleic acids, in particular catalytic RNAs (ribozymes) and DNAs (deoxyribozymes), under extreme and/or unusual conditions that may relate to prebiotic environments.
Glycerol valorization: conversion to lactic acid by heterogeneous catalysis and separation by ion exchange chromatography
Authors: Arcanjo Maria R. A. , da Silva Ivanildo J. , Cavalcante Célio L. , Iglesias José , Morales Gabriel , Paniagua Marta , Melero Juan A. , Vieira Rodrigo S. 
Published: November 2019

AbstractThe consumption and production of biodiesel has grown dramatically in recent decades, motivated by a strong interest in renewable energy. This has generated a surplus of its main by‐product, glycerol. Several catalytic processes have been proposed to generate alternatives for using this excess glycerol, mainly focusing on its transformation into high value‐added chemical products. Various products, ranging from syngas to organic acids, such as acrylic or lactic acid, along with 1,2‐propanediol, 1,3‐propanediol, glycerol ethers or even polymers, have been produced starting from glycerol. Among this multitude of possibilities, the production of lactic acid is one of the most interesting alternatives to valorize glycerol, because of the wide range of applications described for this organic acid. This review focuses on recent studies dealing with the catalytic conversion of glycerol to lactic acid, using different heterogeneous catalysts, and evaluates the factors influencing the oxidation catalytic process and the proposed reaction mechanisms. Finally, recent studies on the separation and purification of lactic acid using ion exchange chromatography resins are also reported. © 2019 Society of Chemical Industry and John Wiley & Sons, Ltd
Italy's nutraceutical industry: a process and bioeconomy perspective into a key area of the global economy
Authors: Pagliaro Mario 
Published: November 2019

AbstractFocusing on the development of Italy's nutraceutical industry, one of Europe's largest, this study offers a process and bioeconomy perspective that will be useful to countries willing to establish their own national dietary supplement industry as a key industrial asset in their economies. © 2019 Society of Chemical Industry and John Wiley & Sons, Ltd
Clinical significance of the presence of puff‐chandelier ruptures detected by nonobstructive aortic angioscopy
Authors: Yamaguchi Masao , Yonetsu Taishi , Hoshino Masahiro , Sugiyama Tomoyo , Kanaji Yoshihisa , Ohya Hiroaki , Hada Masahiro , Sumino Yohei , Kanno Yoshinori , Hirano Hidenori , Yuki Haruhito , Horie Tomoki , Hamaya Rikuta , Usui Eisuke , Sugano Akinori , Murai Tadashi , Lee Tetsumin , Kimura Shigeki , Fujii Hiroyuki , Hikita Hiroyuki , Kakuta Tsunekazu 
Published: November 2019

AbstractObjectiveThis study aimed to investigate the prevalence and prognostic significance of atherosclerotic aortic plaques (AAPs) or specific AAP types detected by nonobstructive angioscopy (NOA) in patients who underwent percutaneous coronary intervention (PCI).BackgroundAlthough recent studies have reported the presence of various patterns of AAPs, identified by NOA, the clinical significance of the presence of AAPs remains elusive.MethodsIn this retrospective, multicenter cohort study, a total of 167 patients who underwent PCI and intra‐aortic scans with NOA were studied. The association between AAPs and the incidence of major adverse cardiac events (MACEs), including cardiac death, myocardial infarction, stroke, and clinically driven unplanned revascularizations, was assessed.ResultsAAPs were detected in 126 patients (75%) who underwent NOA. MACEs occurred in 28 (17%) patients during the follow‐up (median 2.9 years [range 2.1–3.8]). Among all types of AAPs, only puff‐chandelier rupture (PCR) showed a significant difference in frequency between patients with and those without MACEs: 21 (75%) and 49 (35%), respectively (p < .001). Multivariable Cox proportional hazard analysis revealed that PCR (hazard ratio [HR] 3.73, 95% confidence interval [CI] 1.57–8.87, p = .004) and chronic kidney disease (HR 2.97, 95% CI 1.37–6.44, p = .010) were independent predictors of MACEs. Kaplan–Meier analysis revealed that PCR was significantly associated with more frequent MACEs.ConclusionThe detection of PCR in the aorta using NOA was significantly associated with an increased risk of subsequent adverse events after PCI.
Pseudocapacitance‐Enhanced Anode of CoP@C Particles Embedded in Graphene Aerogel toward Ultralong Cycling Stability Sodium‐Ion Batteries
Authors: Hao Siyue , Li Huijun , Zhao Zhenxin , Wang Xiaomin 
Published: November 2019

AbstractDeveloping an anode material with long‐cycling stability and excellent rate performance is critical for enhancing the Na+ storage performance. Herein, an effective method is applied to prepare the carbon‐coated CoP embedded into graphene aerogel (CoP@C/GA) as an anode material for sodium‐ion batteries (SIBs). GA network with large specific surface area and cross‐linked pores provides sites for loading CoP@C, which reduces the agglomeration of CoP@C and accelerates the electron and ion transfer kinetics. The CoP@C particles with abundant pores help to buffer the volume change of CoP during the Na+ insertion/extraction. Meanwhile, CoP crystal particles break down and become smaller during the long‐cycling, resulting in an increase of contact area with the electrolyte. Therefore, the CoP@C/GA anode exhibits ultralong cycling stability (172.8 mAh g−1 at 2000 mA g−1 over 4000 cycles with capacity retention ratio of 115.2 %), and superior rate performance (gradually increasing from 50 mA g−1 to 2000 mA g−1 and returning to 50 mA g−1, the capacity retention rate is 94.1 %). Furthermore, the storage mechanism of CoP@C/GA is mainly controlled by pseudocapacitive behavior, which leads to a rapid Na+ insertion/extraction and excellent rate performance. The prominent cycling stability of CoP@C/GA provides a bright prospect in SIB.