bluuebunny/crossref_metadata_2025_split huggingface dataset:
O fantasma do cárcere: percepção ambiental da enseada de Dois Rios, Ilha Grande (RJ).
Authors: Farias Ana Beatriz Costa , Da Gama Sonia Vidal Gomes 
Published: October 2019

O presente trabalho tem como tema a percepção ambiental, articulada com os conceitos de paisagem cultural e o histórico de uso e ocupação do solo. Dentro do território insular da Ilha Grande, Angra dos Reis (RJ), destacam-se as unidades prisionais, as unidades de conservação e a atividade turística que resultam em uma morfodinâmica dos acontecimentos de forma singular, e são expressadas em diversos imaginários sobre o espaço. O objetivo é analisar as relações deste imaginário, quando veiculado aos usos das agências de viagens, com as percepções dos visitantes na enseada de Dois Rios. A metodologia está sustentada em dois autores: Paulo César da Costa Gomes e Yi-Fu Tuan. O primeiro auxiliando na inventariação dos patrimônios – tratados como paisagens culturais e com funções de atrativos turísticos – a partir dos discursos utilizados pelas agências; e o segundo, no intuito de trazer para a Geografia o sentimento pelo lugar, na perspectiva fenomenológica, exercendo a percepção do visitante, a partir de um questionário voltado para a sua capacidade de sentir e perceber o ambiente através dos seus sentidos, e reconhecer seu conhecimento ambiental. Os resultados apresentam diferentes interpretações dos patrimônios, e relações entre o homem e os atrativos, apontando um contato que, na maioria das vezes, se distancia, e em casos pontuais, aproxima-se com as ideias já propagadas pelo turismo no território insular.PALAVRAS-CHAVE: Turismo, Uso e Ocupação, Paisagem Cultural. ABSTRACTThe present work has as its theme the environmental perception articulated with the concepts of cultural landscape and the historic land’s use and occupation. In the insulate territory of Ilha Grande, Angra dos Reis (RJ), point out the prison units, conservation units, and tourism activity that result in a morphodynamic singular way of the events, and are expressed in several imaginaries about the space. The objective is to analyze the relationships of this imaginary, when conveyed to the uses of travel agencies, with the perceptions of visitors in Dois Rios cove. The methodology is supported by two authors: Paulo César da Costa Gomes and Yi-Fu Tuan. The first assisting in the inventory of assets - treated as cultural landscapes and functions of tourist attractions - from the speeches used by agencies; and the second, in order to bring to Geography the feeling about the place, in the phenomenological perspective, exercising the perception of the visitors from a questionnaire focused on their ability to feel and notice through their senses, and recognize their environmental knowledge. The results presents different interpretations of the assets, and relations between the man and the attractions, pointing to a contact that, in most cases, distances itself, and in specific cases, is approaching the ideas already propagated by tourism in the insulate territory.KEYWORDS: Tourism, Use and Occupation, Cultural Landscape.
Neural precursors of decisions that matter—an ERP study of deliberate and arbitrary choice
Authors: Maoz Uri , Yaffe Gideon , Koch Christof , Mudrik Liad 
Published: October 2019

The readiness potential (RP)—a key ERP correlate of upcoming action—is known to precede subjects' reports of their decision to move. Some view this as evidence against a causal role for consciousness in human decision-making and thus against free-will. But previous work focused on arbitrary decisions—purposeless, unreasoned, and without consequences. It remains unknown to what degree the RP generalizes to deliberate, more ecological decisions. We directly compared deliberate and arbitrary decision-making during a $1000-donation task to non-profit organizations. While we found the expected RPs for arbitrary decisions, they were strikingly absent for deliberate ones. Our results and drift-diffusion model are congruent with the RP representing accumulation of noisy, random fluctuations that drive arbitrary—but not deliberate—decisions. They further point to different neural mechanisms underlying deliberate and arbitrary decisions, challenging the generalizability of studies that argue for no causal role for consciousness in decision-making to real-life decisions.Editorial note: This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that all the issues have been addressed (<xref ref-type="decision-letter" rid="SA1">see decision letter</xref>).
High-responsivity turbostratic stacked graphene photodetectors using enhanced photogating
Authors: Shimatani Masaaki , Yamada Naoki , Fukushima Shoichiro , Okuda Satoshi , Ogawa Shinpei , Ikuta Takashi , Maehashi Kenzo 
Published: October 2019

Abstract
High-responsivity graphene photodetectors were fabricated using turbostratic stacked graphene, which provided enhanced photogating. Photogating is a promising means of increasing the responsivity of graphene photodetectors, and this effect is proportional to carrier mobility. Turbostratic stacked graphene exhibits higher carrier mobility than conventional monolayer graphene because it has the same band structure as monolayer graphene while preventing scattering by the underlying SiO2 layer. The photoresponse of these devices at a wavelength of 642 nm was approximately twice that obtained for a conventional monolayer graphene photodetector. The results reported show the feasibility of producing high-responsivity graphene-based photodetectors using a simple fabrication technique.
Mitochondrial carriers of Ustilago maydis and Aspergillus terreus involved in itaconate production: same physiological role but different biochemical features
Authors: Scarcia Pasquale , Gorgoglione Ruggiero , Messina Eugenia , Fiermonte Giuseppe , Blank Lars Mathias , Wierckx Nick , Palmieri Luigi , Agrimi Gennaro 
Published: October 2019

Itaconic acid (IA) is a naturally occurring dicarboxylic acid with applications in the manufacture of polymers. IA can be produced by fermentation using the fungi Aspergillus terreus or Ustilago maydis as biocatalysts. Indirect evidence has suggested that the mitochondrial carriers U. maydis Um_Mtt1 and A. terreus At_MttA export mitochondrially synthesized cis‐aconitate to the cytosol for IA synthesis using malate as a countersubstrate. Here, by assaying the transport features of recombinant Um_Mtt1 and At_MttA in reconstituted liposomes, we find that both proteins efficiently transport cis‐aconitate, but malate is well transported only by Um_Mtt1 and 2‐oxoglutarate only by At_MttA. Bioinformatic analysis shows that Um_Mtt1 and At_MttA form a distinctive mitochondrial carrier subfamily. Our data show that although fulfilling the same physiological task, Um_Mtt1 and At_MttA have different biochemical features.
Direct Visualization of Optical Activity in Chiral Substances Using a Helical Nanofilament (B4) Liquid Crystal Phase
Authors: Park Wongi , Wolska Joanna M. , Pociecha Damian , Gorecka Ewa , Yoon Dong Ki 
Published: October 2019

AbstractDetecting the chirality of material is very important in material science, chemistry, pharmacology, and biomaterial science because it is useful for identifying and discarding unintended side effects. Here, directly visualized is the optical activity of chiral samples using an orientation‐controlled helical nanofilament (HNF, B4) liquid crystal (LC) phase made of achiral bent‐shaped molecules. The vertical orientation of the HNFs is induced by shining unpolarized UV light. Right‐ or left‐handed domains of the HNFs are formed because of the lack of molecular chirality, each single‐handed domain is large enough to be seen with the naked eye, up to ≈several mm2. The periodic arrays of aligned HNFs reflect a specific color, here green, due to the Bragg reflection. Such a reflector enables an easy detection of optical activity of a sample placed on it. The device is tested with naturally chiral substances, like fructose and glucose, which exhibit opposite sense of optical activity, as well as with structurally chiral nematic LC phase and reveals high sensitivity of a detection.
Fine‐tuned, molecular‐composite, organosilica membranes for highly efficient propylene/propane separation via suitable pore size
Authors: Guo Meng , Kanezashi Masakoto , Nagasawa Hiroki , Yu Liang , Yamamoto Kazuki , Gunji Takahiro , Tsuru Toshinori 
Published: October 2019

AbstractFine‐tuned, molecular‐composite, organosilica membranes were fabricated via the co‐condensation of organosilica precursors bis(triethoxysilyl)acetylene (BTESA) and bis(triethoxysilyl)benzene (BTESB). Fourier transform infrared and UV–vis spectra confirmed the co‐condensation behaviors of BTESA and BTESB. The evolution of the network structure indicated that the incorporated BTESB decreased the membrane pore size, which was determined by a modified gas translation model according to the steric effect of the phenyl groups. The incorporation of BTESB to BTESA finely tuned the membrane structure and endowed the resultant composite membrane with improved separation properties. The BTESAB 9:1 membrane (molar ratio of BTESA/BTESB was 9:1) exhibited high C3H6 permeance at 4.5 × 10−8 mol m−2 s−1 Pa−1 and a C3H6/C3H8 permeance ratio of 33 at 50°C. One of the most important developments of this study involved clearly defining the relationship between membrane pore size and C3H6/C3H8 separation performance for organosilica membranes in single and binary separation systems.
Evaporative Cooling and Self‐Thermalization in an Open System of Interacting Fermions
Authors: Kolovsky Andrey R. , L. Shepelyansky Dima 
Published: October 2019

AbstractDepletion dynamics of an open system of weakly interacting fermions with two‐body random interactions is studied. In this model, fermions are escaping from the high‐energy one‐particle orbitals, that mimics the evaporation process used in laboratory experiments with neutral atoms to cool them to ultra‐low temperatures. It is shown that due to self‐thermalization the system instantaneously adjusts to the new temperature which decreases with the course of time.
Deriving Structure‐Performance Relations of Chemically Modified Chitosan Binders for Sustainable High‐Voltage LiNi0.5Mn1.5O4 Cathodes
Authors: Kuenzel Matthias , Porhiel Regis , Bresser Dominic , Asenbauer Jakob , Axmann Peter , Wohlfahrt‐Mehrens Margret , Passerini Stefano 
Published: October 2019

AbstractThe implementation of aqueous electrode processing for lithium‐ion positive electrodes is key towards the realization of environmentally benign and cheap battery production. One of the water‐soluble binders that has attracted most attention is chitosan, the second‐most abundant natural biopolymer. Herein, the use of chitosan for high‐voltage, cobalt‐free LiNi0.5Mn1.5O4 cathodes is reported for the first time. A detailed comparison of three different grades of chitosan with varying chain length and degrees of deacetylation (DD) is provided to explore the impact of these properties on the electrochemical performance. In fact, bio‐derived chitosan with a relatively lower DD outperforms synthetic chitosan‐especially after crosslinking with citric acid‐yielding about 10 % higher capacities. Higher molecular weight appears additionally advantageous for the cycling stability. Finally, guar gum is employed as slurry thickener, co‐crosslinking with chitosan. This allows for achieving 50 % higher mass loadings than for chitosan only and stable capacities above 130 and 120 mAh g−1 at C/3 and 1 C, respectively.
Prognosis in triple‐negative apocrine carcinomas of the breast: A population‐based study
Authors: Wu Wenyu , Wu Meiying , Peng Guowen , Shi Degang , Zhang Jian 
Published: October 2019

AbstractBackgroundTriple‐negative apocrine carcinoma (TNAC) of the breast is a very rare type of breast cancer. Furthermore, the clinicopathological features, prognosis, and potential impact of treatment strategies in TNAC remain unclear.MethodsData from the Surveillance, Epidemiology, and End Results (SEER) program were used to identify breast cancer patients diagnosed between 2010 and 2016 with TNAC and triple‐negative breast cancer (TNBC, IDC [invasive ductal carcinoma], NOS [not otherwise specified]). Chi‐squared tests were used to examine the categorical variables between the two groups. Overall survival (OS) of TNAC and TNBC was assessed by Kaplan‐Meier analyses and Cox regression. Breast cancer‐specific survival (BCSS) was evaluated by Nelson‐Aalen analyses and competing risk regression.ResultsWe identified 31 362 patients from the SEER database, including 366 patients with TNAC and 30 996 patients with TNBC. TNAC was correlated with older age, lower T stage and lower tumor grade. Patients with TNAC had better OS compared with TNBC patients; the 5‐year OS rates were 82.2% vs 73.5% (P < .001). The breast cancer‐related death rate was significantly lower in patients with TNAC than in patients with TNBC, with a 5‐year cumulative incidence of 9.1% vs 22.9% (P < .001). Chemotherapy was significantly associated with improved OS in TNAC patients, but radiotherapy was not associated with OS in TNAC patients. In the multivariable Cox regression, TNAC was still associated with improved OS (HR [hazard ratio], 0.61; 95% CI [confidence interval] 0.45‐0.83; P = .002). In the multivariable competing risk regression, the significantly higher BCSS in patients with TNAC compared patients with TNBC remained (subdistribution HR [SHR], 0.42; 95% CI, 0.27‐0.64; P < .001).ConclusionPatients with TNAC had a better prognosis than patients with TNBC, and chemotherapy was associated with survival advantages in TNAC patients.
High expression of ALDH1A3 might independently influence poor progression‐free and overall survival in patients with glioma via maintaining glucose uptake and lactate production
Authors: Ni Wei , Xia Yaoxiong , Luo Lin , Wen Fan , Hu Dong , Bi Yuxu , Qi Junhui 
Published: October 2019

AbstractRecent studies have found that the acetaldehyde dehydrogenase 1A3 (ALDH1A3) gene is a marker of glioma stem cells. A total of 115 brain glioma specimens were collected and classified into grade I–IV, while non‐tumor brain tissue specimens, taken from 12 patients of vascular malformation surgery, were used as control. ALDH1A3 gene promoter methylation in glioma tissues was detected by pyrosequencing, while immunohistochemistry and western blot were used to detect ALDH1A3 protein expressions in different grades of glioma tissues and normal brain tissues. The expression of ALDH1A3 in the glioma cell line U87 was detected by quantitative real‐time polymerase chain reaction and RNA‐Seq technology was applied to investigate differentially expressed genes before and after silencing the ALDH1A3 gene. Among the 115 glioma tissue specimens, 50 (43.48%) showed low and 65 (56.52%) high expression of ALDH1A3, but no expression was detected in the control. Univariate and multivariate COX regression analyses showed that the patient's tumor pathological grade, the methylation status of ALDH1A3 promoter, and the expression of ALDH1A3 protein were risk factors for progression‐free survival (PFS) and overall survival (OS) (all P < 0.05) and the OS of mice with silenced ALDH1A3 in a glioma nude mouse model was prolonged. U87 experiments revealed that ALDH1A3 expression had significant effects on apoptosis, proliferation, cell cycle, mitochondrial membrane potential, glucose consumption, lactate production, invasion ability, and expression of the pyruvate kinase M2 (PKM2) and hexokinase 2 (HK2) in glioma cells. ALDH1A3 protein expression is a marker for poor PFS and OS in glioma patients.
Assessment of repeat target lesion percutaneous coronary intervention as a quality measure for public reporting and general quality assessment for PCIs
Authors: Hannan Edward L. , Zhong Ye , Ling Frederick S. K. , Tamis‐Holland Jacqueline , Berger Peter B. , Jacobs Alice K. , Walford Gary , Venditti Ferdinand J. , King Spencer B. 
Published: October 2019

AbstractBackgroundTarget lesion percutaneous coronary intervention (TLPCI) within 1 year of PCI has been proposed by critics of public reporting of short‐term mortality as an alternative measure for PCI reporting.MethodsNew York's PCI registry was used to identify 1‐year repeat TLPCI and 1‐year repeat TLPCI/mortality for patients discharged between December 1, 2013 and November 30, 2014. Significant independent predictors of the outcomes were identified. Hospital and cardiologist risk‐adjusted outcomes were calculated, and outlier status and correlations of risk‐adjusted rates were examined for the three outcomes.ResultsThe adverse outcome rates were 1.30, 4.21, and 8.97% for in‐hospital/30‐day mortality, 1‐year repeat TLPCI, and 1‐year repeat TLPCI/mortality. There were many commonalities but also many differences in significant predictors of the outcomes. Hospital and cardiologist risk‐adjusted 1‐year repeat TLPCI rates and repeat TLPCI/mortality rates were poorly correlated with risk‐adjusted in‐hospital/30‐day mortality rates (eg, Spearman R = −.16 [p = .23] and .27 [p = .04], respectively, for hospital 1‐year repeat TLPCI vs. in‐hospital/30‐day mortality). Many more providers were found to have significantly higher and lower rates for repeat TLPCI than for short‐term mortality.ConclusionsHospital and cardiologist quality assessments are very different for TLPCI and repeat TLPCI/mortality than they are for short‐term mortality. Repeat TLPCI/mortality rates are highly correlated with repeat TLPCI rates, but outlier providers differ. More study of repeat TLPCI and all the patient, cardiologist, and hospital factors associated with it may be required before using it as a supplement to, or in lieu of, short‐term mortality in public reporting of PCI outcomes.
Local and generalized sensitization of thermally evoked defensive behavior in caterpillars
Authors: Mukherjee Ritwika , Trimmer Barry A. 
Published: October 2019

AbstractIn addition to camouflage and chemical toxicity, many caterpillars defend themselves against predators with sudden sharp movements. For smaller species, these movements propel the body away from the threat, but in larger caterpillars, such as the tobacco hornworm, Manduca sexta, the movement is a defensive strike targeted to a noxious stimulus on the abdomen. Previously, strikes have been studied using mechanical stimulation like poking or pinching the insect, but such stimuli are hard to control. They also introduce mechanical perturbations that interfere with measurements of the behavior. We have now established that strike behavior can be evoked using infra‐red lasers to provide a highly localized and repeatable heat stimulus. The latency from the end of an effective stimulus to the start of head movement decreased with repeated stimuli and this effect generalized to other stimulus locations indicating a centrally mediated component of sensitization. The tendency to strike increased with two successive subthreshold stimuli. When delivered to different locations or to a single site, this split‐pulse stimulation revealed an additional site‐specific sensitization that has not previously been described in Manduca. Previous work shows that strong stimuli increases the effectiveness of sensory stimulation by activating a long‐lasting muscarinic cation current in motoneurons. Injection of muscarinic cholinergic antagonists, scopolamine methyl bromide or quinuclidinyl benzilate, only decreased the strike probability evoked by paired stimuli at two locations and not at a single site. This strongly suggests a role of muscarinic acetylcholine receptors in the generalized sensitization of nociceptive responses in caterpillars.
Crystal Structure and Reversible Photochromism of Pb(II)‐N,N‐Dimethylformamide Modified Keggin‐Type Polyoxometalates
Authors: Pang Tao , Zhou Zhen , Li Dong , Liu Hong , Zhang Zhanshu , Qi Liwei , Song Chao‐Yu , Gao Guang‐Gang , Lv Yuguang 
Published: October 2019

AbstractTwo Pb(II)‐DMF complex modified Keggin‐type polyoxometalate compounds, [Pb(DMF)7]2[SiW12O40] 2DMF (1) and [Pb(DMF)4(H2O)2][Pb2(μ2‐DMF)2(DMF)8][PW12O40]2 (2) (DMF = N,N‐dimethylformamide), have been demonstrated in this work. Both 1 and 2 are characterized by X‐ray single crystal diffraction, Fourier transform infrared (FTIR), and UV–vis spectra, and elemental analyses. The crystal structure analysis indicates that compound 1 is composed of Pb(II)‐DMF complex and Keggin‐type [SiW12O40]4− polyoxoanion, in which the Pb2+ coordinates to the polyoxoanion by different Pb−O bonds, while compound 2 is composed of [Pb(DMF)4(H2O)2]2+, dimeric [Pb2(μ2‐DMF)2(DMF)8]4+ cations, and two kinds of Keggin‐type [PW12O40]2− polyoxoanions. By ultraviolet irradiation, both 1 and 2 display the reversible color change from white (for 1) or light yellow (for 2) to blue, which can be applied as new crystalline photochromic materials. Upon heating, the blue color of the two compounds can be recovered within 5 min. The successful syntheses of compounds 1 and 2 provide a new route for the design and synthesis of reversible photochromic crystalline materials.
Fossil evidence of evolutionary convergence in juvenile dental morphology and upper canine replacement in sabertooth carnivores
Authors: Wysocki Matthew Aleksander 
Published: October 2019

AbstractThe convergent suite of morphological traits characterizing the mammalian sabertooth ecomorphology is well documented, including modifications of the dental and osteological portions of the masticatory apparatus from a less‐specialized carnivore condition. Equally important is how those specialized adult morphologies developed through ontogeny because previous studies have shown that growing such specialized craniodental traits may require evolutionary modification of growth patterns and tooth replacement mechanisms. Despite the understanding of convergent morphological specialization in adult sabertooth carnivores, the possibility of a convergent ontogenetic trajectory toward those adult morphologies has not been rigorously examined. The present study examines numerous previously undescribed juvenile nimravid specimens. The results provide insights about nimravid ontogeny and show, for the first time, that the nimravid sabertooth lineage included species in which the permanent upper canine erupted within a lingual concavity of the deciduous upper canine until it reached comparable crown height beyond the alveolar border. Furthermore, this investigation assesses the juvenile morphology and upper canine replacement of felid and barbourofelid sabertooth taxa. The results provide evidence of convergence in deciduous upper canine morphology of three sabertooth carnivore lineages (i.e., nimravid, felid, and barbourofelid), as well as preliminary evidence of convergence in the upper canine replacement process. It might be beneficial for studies of extreme morphological specialization to simultaneously consider convergence in adult morphologies and how morphologies change through ontogeny.