bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexual Behavior Problems and Premature Termination From Pediatric Trauma‐Focused Treatment Among Sexually Abused Children
Authors: Wamser‐Nanney Rachel 
Published: June 2020

AbstractPremature termination from child trauma‐focused treatment is common; however, the role of children's level of symptoms as a risk factor for attrition remains uncertain. In particular, children's sexual behavior problems (SBPs) have received scant attention in the prior attrition literature, and no known studies to date have thoroughly examined SBPs in relation to premature treatment termination. The current study investigated whether higher levels of children's SBPs were associated with increased risk for attrition from trauma‐focused treatment in a sample of 242 sexually abused children aged 2–12 years (M = 7.48 years, SD = 2.68; 64.5% female, 54.1% White). To assess the potential associations between SBPs and treatment dropout more thoroughly, two definitions of attrition were utilized: (a) clinician‐rated dropout and (b) whether the child received an adequate dose of treatment (i.e., 12 or more sessions). Whereas only 34.3% of the children completed treatment per their clinician, 69.4% received an adequate dose of treatment. In contrast to the study hypotheses, neither development‐related nor sexual abuse–specific SBPs were associated with either clinician‐rated dropout or adequate dose status, ORs = 0.99–1.00. Sexual acting‐out behaviors in sexually abused children may not correspond with attrition from trauma‐focused treatment at multiple points of treatment. Given the heterogeneity of SBPs, further assessment of whether attrition patterns differ across subgroups of children who exhibit SBPs is needed.
Pharmaceutical Formulation and Characterization of Dipeptide Nanotubes for Drug Delivery Applications
Authors: Porter Simon L. , Coulter Sophie M. , Pentlavalli Sreekanth , Laverty Garry 
Published: June 2020

AbstractPeptide nanotubes are promising materials for a variety of biomedical applications with ultrashort (≤7 amino acids) forms providing particular promise for clinical translation. The manufacture of peptide nanotubes has, however, been associated with toxic organic solvents restricting clinical use. The purpose of this work is to formulate dipeptide nanotubes using mild techniques easily translated to industrial upscale and to characterize their physiochemical and biological properties. Phenylalanine‐phenylalanine variants can be successfully formulated using distilled water as demonstrated here. Formulations are homogenous in shape (tubular), with apparent size (50–260 nm) and a zeta potential of up to +30 mV. L‐(H2N‐FF‐COOH), and D‐enantiomers (H2N‐ff‐COOH) demonstrate no toxicity against glioblastoma cells and are explored for ability to deliver a model hydrophilic molecule, sodium fluorescein, at pH 5.5 (tumor) and 7.4 (physiological). Peptide nanotubes loaded with >85% sodium fluorescein, demonstrate burst release characteristics, fitting the Weibull model of drug release. This research provides important data contributing to the pharmaceutical formulation of peptide nanotubes as drug delivery platforms for hydrophilic drugs.
Mussel‐Inspired Biocoating for Improving the Adhesion of Dental Pulp Stem Cells in Dental Pulp Regeneration
Authors: Liu Yanan , Qiu Ying , Ni Shilei , Zhang Xuewei , Sun Hongchen , Song Wenlong , Li Xiangwei 
Published: June 2020

AbstractDental pulp engineering possesses a promising perspective to replacing lost pulp in the root canal and restoring its functions. Stable adhesion of dental pulp stem cells (DPSCs) on the root canal dentin wall is a key element required for reconstruction of a functional odontoblast layer in dental pulp regeneration. To address this challenge, dopamine‐modified hyaluronic acid (DA‐HA) is coated on dentin to obtain a stable adhesion of DPSCs. The dopamine segment provides adhesion ability to the coating, and the hyaluronic acid increases the biocompatibility. The results show that DPSCs can adhere on the DA‐HA coated dentin slice better than those without coating. Simultaneously, DPSCs proliferation can be further promoted on the prepared coating. Therefore, the DA‐HA coating may provide a possible way to immobilize odontoblast cell onto dentin surface for pulp regeneration.
HSPA1A gene polymorphism rs1008438 is associated with susceptibility to acute mountain sickness in Han Chinese individuals
Authors: Liu Zhicheng , Chen Hong , Xu Ting , Wang Xiaomei , Yao Chunyan 
Published: June 2020

AbstractBackgroundAcute mountain sickness (AMS) usually occurs among non‐acclimated individuals after rapid ascending to high‐altitude environments (generally ≥2,500 m). However, the precise molecular mechanism of AMS remains unclear. Our study aimed to investigate the relationship between several single nucleotide polymorphisms (SNPs) and AMS susceptibility.MethodsIn this work, sequencing data were obtained from 69 AMS patients and 95 matched acclimated Han Chinese individuals from southwest China. Five SNPs (rs1008438, rs150877473, rs1799983, rs2153364, and rs3025039) were systematically investigated in all the participants.ResultsIn our study, we found that allele frequencies of “A” (AMS 69.57% vs. non‐AMS 54.74%) and “C” (AMS 30.43% vs. non‐AMS 45.26%) in the HSPA1A gene rs1008438 were significantly different between the AMS and non‐AMS groups (p = .01). Genotypes “CC” and “CA” of the HSPA1A gene (rs1008438) were associated with lower risk of developing AMS than the genotype “AA.” Comparing the genotypes “CC + CA” and “AA,” we also observed that the “CC + CA” genotype of rs1008438 was associated with lower AMS risk.ConclusionsIn our case‐control study, there was a significant association between the rs1008348 polymorphism and AMS susceptibility, suggesting that this particular SNP might be a Han‐specific risk factor for AMS. We believe that this study establishes a foundation for further elucidation of the genetic mechanisms underlying AMS.
Thermodynamic Effects on Grade Transition of Polyethylene Polymerization in Fluidized Bed Reactors
Authors: Kardous Sabrine , McKenna Timothy F. L. , Sheibat‐Othman Nida 
Published: June 2020

AbstractAn off‐line dynamic optimization procedure is employed to optimize the transition between different grades of linear low density polyethylene in a fluidized bed reactor. This type of reactor is frequently operated under condensed mode, which consists of injecting induced condensing agents (ICA) to absorb part of the reaction heat. However, the presence of ICA affects the solubility of monomers in the polymer, so it is important to account for this effect in a grade transition optimization strategy. A kinetic model is combined with a thermodynamic model based on the Sanchez–Lacombe equation of state to describe the grade transitions. Simplified correlations are then suggested to predict the impact of ICA on ethylene and comonomer solubility in a quaternary system. The results highlight the importance of the thermodynamic model during grade transition.
Deep‐learned short tau inversion recovery imaging using multi‐contrast MR images
Authors: Kim Sewon , Jang Hanbyol , Jang Jinseong , Lee Young Han , Hwang Dosik 
Published: June 2020

PurposeTo generate short tau, or short inversion time (TI), inversion recovery (STIR) images from three multi‐contrast MR images, without additional scanning, using a deep neural network.MethodsFor simulation studies, we used multi‐contrast simulation images. For in‐vivo studies, we acquired knee MR images including 288 slices of T1‐weighted (T1‐w), T2‐weighted (T2‐w), gradient‐recalled echo (GRE), and STIR images taken from 12 healthy volunteers. Our MR image synthesis method generates a new contrast MR image from multi‐contrast MR images. We used a deep neural network to identify the complex relationships between MR images that show various contrasts for the same tissues. Our contrast‐conversion deep neural network (CC‐DNN) is an end‐to‐end architecture that trains the model to create one image from three (T1‐w, T2‐w, and GRE images). We propose a new loss function to take into account intensity differences, misregistration, and local intensity variations. The CC‐DNN‐generated STIR images were evaluated with four quantitative evaluation metrics, including mean squared error, peak signal‐to‐noise ratio (PSNR), structural similarity (SSIM), and multi‐scale SSIM (MS‐SSIM). Furthermore, a subjective evaluation was performed by musculoskeletal radiologists.ResultsOur method showed improved results in all quantitative evaluations compared with other methods and received the highest scores in subjective evaluations by musculoskeletal radiologists.ConclusionThis study suggests the feasibility of our method for generating STIR sequence images without additional scanning that offered a potential alternative to the STIR pulse sequence when additional scanning is limited or STIR artifacts are severe.
Schwingungstechnik und Schrumpffolien
Authors: Bulmahn Maren 
Published: June 2020

AbstractDas Familienunternehmen Freudenberg feierte im Jahr 2019 das 170. Jahr seiner Gründung. Heute produziert der Konzern Dichtungen, Vliesstoffe, Filter, Spezialchemie und Reinigungsprodukte.
Mineral statt Metall in Brennstoffzellen
Authors: Zhang Shifan , Koenders Eddie 
Published: June 2020

AbstractWer bei Brennstoffzellen nur an Metall‐ oder Graphitelektroden denkt, kennt die neuesten Forschungsergebnisse nicht: Denn richtig modifiziert eignen sich auch Zement oder Geopolymere als Trägersubstanzen.
Massenspektrometriker in Münster
Authors: Gross Jürgen 
Published: June 2020

AbstractDie 53. Jahrestagung der Deutschen Gesellschaft für Massenspektrometrie (DGMS) fand in diesem Jahr gemeinsam mit dem 27. ICP‐MS‐Anwendertreffen statt. Zu der viertägigen Veranstaltung Anfang März trafen sich etwa 560 Teilnehmer an der Universität Münster. Die lokale Organisation hatten Uwe Karst und Heiko Hayen (beide Univ. Münster) übernommen. Zusätzlich zu neun Plenarvorträgen, 90 eingereichten Vorträgen in vier parallelen Sessions und 235 Postern in zwei Sessions informierten 19 Firmen aus MS und anderer Analytik an ihren Ständen über Produkte und Neuentwicklungen. Seit der Tagung in Rostock 2019 nutzt die DGMS Englisch als Tagungssprache, um so dem durch Studierende, Wissenschaftler und Plenarvortragende aus aller Welt internationalen Charakter zu entsprechen.
Redoxreaktionen mit dem Springbrunnenversuch
Authors: Ducci Matthias 
Published: June 2020

AbstractDer Klassiker unter den Schulversuchen, der Springbrunnenversuch, lässt sich mit fluoreszierenden Farbstoffen spektakulärer gestalten als mit klassischen pH‐Indikatoren. Aber auch Redoxreaktionen, die in allen Bundesländern auf den Bildungsplänen stehen, setzt ein solcher solcher Versuch in Szene.
Bakelit: der erste seiner Klasse
Authors: Offermanns Heribert , Retzlaff Frank 
Published: June 2020

AbstractAm ersten industriell produzierten Kunststoff lässt sich die historische Rohstoffbasis der industriellen Chemie des 19. und frühen 20. Jahrhunderts erkennen: Die stoffliche Basis für die Bakelitsynthese waren Produkte der Holz‐ und der Teerchemie.
Socioeconomic drivers of urban pest prevalence
Authors: Sutherland Chris , Greenlee Andrew J. , Schneider Daniel 
Published: June 2020

Abstract

Bed bugs have re‐established themselves as a common household pest in the United States and pose significant public health and economic concerns, particularly in urban areas.

Documenting the scale of the bed bug resurgence and identifying the underlying predictors of the spatial patterns of their incidence is challenging, largely because available data come from biased self‐reporting through local government code enforcement.

Here, we make use of a novel source of systematically collected data from periodic inspections of multifamily housing units in Chicago to investigate neighbourhood drivers of bed bug infestation prevalence in Chicago.

Bed bug infestations are strongly associated with income, eviction rates and crowding at the neighbourhood level.

That bed bug prevalence is higher in lower‐income neighbourhoods with higher levels of household crowding and eviction notices provides unique empirical evidence of the disproportionate allocation of public health burdens upon neighbourhoods facing multiple dimensions of disadvantage.

A free Plain Language Summary can be found within the Supporting Information of this article.
A 3D Polymeric Platform for Photonic Quantum Technologies
Authors: Colautti Maja , Lombardi Pietro , Trapuzzano Marco , Piccioli Francesco S. , Pazzagli Sofia , Tiribilli Bruno , Nocentini Sara , Cataliotti Francesco S. , Wiersma Diederik S. , Toninelli Costanza 
Published: June 2020

AbstractThe successful development of future photonic quantum technologies will much depend on the possibility of realizing robust and scalable nanophotonic devices. These should include quantum emitters like on‐demand single‐photon sources and non‐linear elements, provided their transition linewidth is broadened only by spontaneous emission. However, conventional strategies to on‐chip integration, based on lithographic processes in semiconductors, are typically detrimental to the coherence properties of the emitter. Moreover, such approaches are difficult to scale and bear limitations in terms of geometries. Here an alternative platform is discussed, based on molecules that preserve near‐Fourier‐limited fluorescence even when embedded in polymeric photonic structures. 3D patterns are achieved via direct laser writing around selected molecular emitters, with a fast, inexpensive, and scalable fabrication process. By using an integrated polymeric design, detected photon counts of about 2.4 Mcps from a single cold molecule are reported. The proposed technology will allow for competitive organic quantum devices, including integrated multi‐photon interferometers, arrays of indistinguishable single‐photon sources, and hybrid electro‐optical nanophotonic chips.
Overexpression of HSP70 attenuates sarcopenia by suppressing the expression of miR‐133b
Authors: Nascimento Tábata L. , Mestril Ruben , Miyabara Elen H. 
Published: June 2020

AbstractBackgroundThe aim of the present investigation is to evaluate the effect of the overexpression of inducible 70‐kDa heat shock protein (HSP70) on sarcopenic muscles of aged mice.MethodsTibialis anterior muscles of aged and young transgenic mice overexpressing HSP70 and wild‐type mice were evaluated. Old mice were treated with the HSP inducer O‐[3‐piperidino‐2‐hydroxy‐1‐propyl]‐nicotinic amidoxime (BGP‐15) for 10 days, and their muscles were analysed.ResultsOld HSP70 transgenic mice presented a less pronounced decrease in myofiber size, lower protein levels of Foxo3a, and a spared increase in miRNA‐133b expression when compared with old wild‐type mice. Moreover, in BGP‐15‐treated old mice, the reduction in myofiber size was less intense, and the decline in muscle specific force was attenuated.ConclusionsThese results suggest that HSP70 overexpression attenuates sarcopenia in old mice, and this effect may be mediated by miR‐133b down‐regulation. In addition, BGP‐15 treatment may be a useful strategy to mitigate the effects of sarcopenia in old mice.
Controlling Ocean One: Human–robot collaboration for deep‐sea manipulation
Authors: Brantner Gerald , Khatib Oussama 
Published: June 2020

AbstractDeploying robots to explore venues that are inaccessible to humans, or simply inhospitable, has been a longstanding ambition of scientists, engineers, and explorers across numerous fields. The deep sea exemplifies an environment that is largely uncharted and denies human presence. Central to exploration is the capacity to deliver dexterous robotic manipulation to this unstructured environment. Unmanned underwater vehicles (UUVs) are successful in providing passive solutions for observation and mapping but currently are far from capable of delivering human‐level dexterity. The ones providing manipulation typically are UUVs coupled with position‐controlled hydraulic arms using disjoint controllers for navigation and manipulation that require expert operators. Ocean One is a humanoid underwater robot designed specifically for underwater manipulation. In this paper, we present Ocean One's control architecture that, through a collaboration between this humanoid robot and a human pilot, enables the deployment of dexterous robotic manipulation to the deep sea. We provide detailed descriptions of this architecture's two main components: first, a whole‐body controller that creates functional autonomy by coordinating manipulation, posture, and constraint tasks, and second, a set of haptic and visual human interfaces that enable intimate interaction while avoiding micromanagement. We test the presented methods in simulation and validate them in pool experiments and in two field deployments. On its maiden mission into the Mediterranean Sea, Ocean One explored the Lune, a French naval vessel that sank in 1664 off the coast of Toulon, France. In its second expedition, Ocean One assisted human divers in investigating underwater volcanic structures at Santorini, Greece.
Retraction: “Dissolution Behavior of Boron Nitride Inclusions and Segregation of Nb Element in Martensitic Ferritic Steel”
Authors: Ma Yulin , Zhang Jun , Zhang Junjia , Yang Jiaqi , Liu Chunming , Wang Pengzhe 
Published: June 2020

DOI: 10.1002/srin.201900488
The above article from steel research international, published online on 21 November 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor‐in‐Chief, Sandra Kalveram, and John Wiley and Sons Ltd. After publication in EarlyView section, the authors asked for this retraction as they noticed in subsequent experiments that the presented results are not reproduceable.
Hyperforin induces apoptosis through extrinsic/intrinsic pathways and inhibits EGFR/ERK/NF‐κB‐mediated anti‐apoptotic potential in glioblastoma
Authors: Hsu Fei‐Ting , Chen Wei‐Ting , Wu Ching‐Te , Chung Jing‐Gung 
Published: June 2020

AbstractGlioblastoma is the most common primary brain tumor with poor survival rate and without effective treatment strategy. Notably, amplification and active mutation of epidermal growth factor receptor (EGFR) occur frequently in glioblastoma patient that may be a potential treatment target. Several studies indicated that various type of herbal compounds not only regulate anti‐depressant effect but also shown capacity to suppress glioblastoma growth via inducing apoptosis and inhibiting oncogene signaling transduction. Hyperforin, an herb compound derived from St. John's wort was used to treat depressive disorder by inhibiting neuronal reuptake of several neurotransmitters. Although hyperforin can reduce matrix metallopeptidases‐2 (MMPs) and ‐9‐mediated metastasis of glioblastoma, the detail mechanism of hyperforin on glioblastoma is remaining unclear. Here, we suggested that hyperforin may induce extrinsic/intrinsic apoptosis and suppress anti‐apoptotic related proteins expression of glioblastoma. We also indicated that hyperforin‐mediated anti‐apoptotic potential of glioblastoma was correlated to inactivation of EGFR/extracellular signal‐regulated kinases (ERK)/nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) signaling.
Changes in Fish Communities of the Seine Basin over a Long-Term Perspective
Authors: Belliard Jérôme , Beslagic Sarah , Tales Evelyne 
Published: June 2020

AbstractUsing both historical and current data, we retrace the long-term evolution of fish assemblages in the Seine River basin since 1880, from headwaters to upstream of the Seine River estuary. Successive phases are observed, related to anthropogenic impacts on habitat conditions and river water quality. Temporal trajectories were thus reconstructed on several reaches based on the change of the proportion of species’ ecological traits, in order to detect the main drivers of alteration. Contrasted trends occur between large rivers and small streams of the basin. In this context, migratory fish declined, whereas the proportion of non-native species increased in the fish community of the Seine River.
Aquatic Organic Matter in the Seine Basin: Sources, Spatio-Temporal Variability, Impact of Urban Discharges and Influence on Micro-pollutant Speciation
Authors: Varrault G. , Parlanti E. , Matar Z. , Garnier J. , Nguyen P. T. , Derenne S. , Rocher V. , Muresan B. , Louis Y. , Soares-Pereira C. , Goffin A. , Benedetti M. F. , Bressy A. , Gelabert A. , Guo Y. , Cordier M.-A. 
Published: June 2020

AbstractThis research has been conducted over the last 10 years to characterise the spatio-temporal variability of aquatic organic matter (OM) composition in the Seine River watershed upstream and downstream of Paris Megacity and its effect on micro-pollutants. For this purpose, a large number of samples were collected under different hydrological conditions, and, over 1 year, three representative sites were monitored monthly. Furthermore, the evolution of the OM composition along an urbanisation gradient, from upstream to downstream of the Paris agglomeration, was characterised, highlighting the very strong impact of urban discharges, especially during low-water periods. Substantial differences in the chemical composition are emphasised relative to the urban or natural origin of the organic matter. Dissolved organic matter (DOM) interactions with metallic and organic micro-pollutants were studied, allowing us to (1) identify the key role of DOM on their speciation and bioavailability in aquatic systems and (2) demonstrate that these interactions depend on DOM composition and origin. The essential role of urban DOM on the speciation of trace metals in the Seine River downstream of the Paris agglomeration is also shown.
How Should Agricultural Practices Be Integrated to Understand and Simulate Long-Term Pesticide Contamination in the Seine River Basin?
Authors: Blanchoud H. , Schott C. , Tallec G. , Queyrel W. , Gallois N. , Habets F. , Viennot P. , Ansart P. , Desportes A. , Tournebize J. , Puech T. 
Published: June 2020

AbstractModelling long-term pesticide transfer to rivers at the catchment scale is still difficult due to a lack of knowledge of agricultural practices and poorly adapted field observation. The Orgeval experimental catchment was first investigated to validate a modelling approach. In addition to pesticide practices investigated over 20 years, directly collected from farmers, monthly integrated river samples were analysed for 10 years. To explicitly integrate agricultural practices and crop rotation, the STICS crop model was adapted to simulate pesticide transfer in soil. Annual load simulations were compared to observed pesticide fluxes in rivers. To simulate the contamination of groundwater, the STICS-Pest model was coupled to the MODCOU hydrogeological model. The results are discussed at the subbasin scale in relation to available data. To upscale the approach at the Seine River basin scale, other strategies need to be developed.