bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case report of recurrent spontaneous coronary artery dissection and Takotsubo cardiomyopathy: a treatment dilemma
Authors: Ghafoor Hafiz U , Bose Abhishek , El-Meligy Amr , Hannan Joseph 
Published: February 2020

AbstractBackgroundSpontaneous coronary artery dissection (SCAD) is an uncommon cause of acute coronary syndrome in younger females with no pre-existing history of coronary artery disease. Recurrent SCAD is common after a first episode and can involve the same coronary artery or present as a new dissection unrelated to the initial lesion. Current recommendations advise for a conservative approach in the absence of haemodynamic compromise and flow limitations. Conversely, there are no clear guidelines for the management of early recurrent SCAD.Case summaryA 52-year-old woman with history of obesity, asthma, and prediabetes presented with chest pain and electrocardiogram (ECG) showing inferior wall ST-elevation myocardial infarction (STEMI). Coronary angiography revealed proximal right coronary artery (RCA) dissection and distal left anterior descending artery (LAD) dissection, while left ventriculogram showed Takotsubo cardiomyopathy (TC). Angiography revealed no flow limitations so conservative management was pursued. She returned within a couple of days with recurrent chest pain and ECG showing similar findings of inferior STEMI. Repeat angiography confirmed progression of the proximal RCA SCAD with resolution of distal LAD SCAD. Since flow through the distal RCA was still preserved, conservative medical management was continued. She presented a third time for palpitations only and another repeat coronary angiogram showed healing RCA SCAD.DiscussionManagement of early recurrent SCAD continues to be a clinical dilemma. In addition, our patient had features of TC which shares a similar clinical risk factor profile with SCAD thus it may be prudent to further investigate for TC in patients presenting with SCAD and have suggestive features of TC on history and echocardiography.
Feasibility of novel transapical off pump beating heart mitral valve repair in a patient with dextrocardia and situs inversus
Authors: Bhatia Inderjeet , Chan Daniel Tai-Leung , Lam Simon Chi-Cheung , Au Timmy Wing-Kuk 
Published: February 2020

Abstract
We present a case to demonstrate the feasibility of transapical beating heart mitral valve repair in a patient with dextrocardia. This minimally invasive technique provides simple, safe and satisfactory mitral repair. The surgical technique, outcome and prognosis are not affected by the condition.
Proceedings from the 3rd European Clinical Consensus Conference for clinical trials in device-based hypertension therapies
Authors: Mahfoud Felix , Azizi Michel , Ewen Sebastian , Pathak Atul , Ukena Christian , Blankestijn Peter J , Böhm Michael , Burnier Michel , Chatellier Gilles , Durand Zaleski Isabelle , Grassi Guido , Joner Michael , Kandzari David E , Kirtane Ajay , Kjeldsen Sverre E , Lobo Melvin D , Lüscher Thomas F , McEvoy John William , Parati Gianfranco , Rossignol Patrick , Ruilope Luis , Schlaich Markus P , Shahzad Atif , Sharif Faisal , Sharp Andrew S P , Sievert Horst , Volpe Massimo , Weber Michael A , Schmieder Roland E , Tsioufis Costas , Wijns William 
Published: February 2020

Abstract
Food components and diet habits: chief factors of cancer development
Authors: Ksouri Rihab 
Published: February 2020

AbstractFood is a vital need for everyone. Today, there is food for all, but the world still suffers from under- and over-nutrition and risk of cancer development and chronic diseases can follow both cases. Worldwide, cancer is a leading cause of mortality after cardiovascular disease; it is considered the second reason for death globally. Role of nutritional habits, the quality of food, the consumption of canned foods, genetically modified fruits and vegetables and exposed food to certain pesticides and carcinogens agents, and unhealthy lifestyle behaviours such as smoking, alcohol, obesity, and fast-foods consumption may be at risk to the development of some cancers. In recent decades, researchers have carried out attention in this field to improve the quality of life and to limit nutrition problems. Thus, this study aims to summarize current evidence on the relationship between nutritional factors and cancer expansion, how nutrition can be a heal and a source of fatal illness leading to death. In detail, this review will highlight the influence of specific foodstuffs on the threat of cancer incidence and recurrence by providing some examples of most carcinogenic compounds.
Finite element error analysis of wave equations with dynamic boundary conditions:L2 estimates
Authors: Hipp David , Kovács Balázs 
Published: February 2020

Abstract$L^2$ norm error estimates of semi- and full discretizations of wave equations with dynamic boundary conditions, using bulk–surface finite elements and Runge–Kutta methods, are studied. The analysis rests on an abstract formulation and error estimates, via energy techniques, within this abstract setting. Four prototypical linear wave equations with dynamic boundary conditions are analysed, which fit into the abstract framework. For problems with velocity terms or with acoustic boundary conditions we prove surprising results: for such problems the spatial convergence order is shown to be less than 2. These can also be observed in the presented numerical experiments.
Determination of Naringin and Neohesperidin in Orange Juice by Liquid Chromatography with UV Detection to Detect the Presence of Grapefruit Juice: Collaborative Study
Authors: Widmer Wilbur ,   Collaborators:, Brause A , Coppola E , Daniels K , Feicht R , Hendricks S , Kirksey S T , Kline L L , Krueger D , Martin S F , Matos J , Metcalf L , Nolan S , Smith C , Smith R , Trama T 
Published: February 2020

Abstract
Fifteen collaborating laboratories were sent 9 samples of citrus juice mixtures as blind duplicates for determination of naringin and neohesperidin by liquid chromatography. Two sample pairs were 100% orange juice and did not contain any naringin or neohesperidin. The remaining 7 sample pairs contained naringin at levels ranging from 3.9 to 46.5 ppm and neohesperidin at levels ranging from 0.14 to 35.6 ppm. Five sample pairs consisted of orange juice mixtures containing 1, 3, and 5% grapefruit juice; 5% sour orange; and 5% K-Early citrus variety. Two sample pairs were orange juice spiked with naringin, neohesperidin, sodium benzoate, and potassium sorbate. Data were received from 13 laboratories. Data from 1 collaborator were eliminated because the method protocol was not followed. Neohesperidin values from another laboratory were also not used because of problems with a coeluting component. Repeatability relative standard deviations ranged from 2.95 to 15.23% for naringin and from 3.00 to 11.74% for neohesperidin. Reproducibility relative standard deviations ranged from 11.34 to 31.94% for naringin and from 10.45 to 26.17% for neohesperidin. The method is reliable for detecting the presence of grapefruit juice in orange juice as indicated by a finding of ≥10 ppm naringin and ≤2 ppm neohesperidin. The method was adopted First Action by AOAC INTERNATIONAL.
Validation of the Microbiological Methods Hygicult Dipslide, Contact Plate, and Swabbing in Surface Hygiene Control: A Nordic Collaborative Study
Authors: Salo Satu , Laine Annikki , Alanko Timo , Sjöberg Anna-Maija , Writanen Gun ,   Collaborators:, Guðbjörnsdóttir B , Jessen B , Langsrud S , Lindquist K , Lundén J , Mäki M , Nerbrink E , Niclasen Ó , Tuominen P , Tuompo H , Vatunen E , Woivalin A 
Published: February 2020

Abstract
A collaborative study on total aerobic bacterial count was conducted to validate the Hygicult® TPC dipslide against contact plates and swabbing, using stainless-steel surfaces artificially contaminated with different microbes at various levels. Twelve laboratories took part in the validation procedure. The total number of collaborative samples was 108. The microbial level in each sample was assessed in triplicate using the 3 above-mentioned methods under 3 different incubation conditions (at 25 ± 1°C for 48 and 72 h and at 30 ± 1°C for 48 h). Surface sampling methods detached 25–30% at the lowest (theoretical yield, 1.4 cfu/cm2), 18–20% at the middle (theoretical yield, 10.7 cfu/cm2), and 16–21% at the highest (theoretical yield, 43.6 cfu/cm2) levels of microbes from the test surfaces. The percentage of acceptable results after removing outliers was 89%. Repeatability standard deviations ranged from 27.2 to 74.6% and reproducibility standard deviations ranged from 42.1 to 97.5%. There were no significant differences between results obtained at different incubation temperatures (25 and 30°C) or incubation times (48 and 72 h) for all 3 methods. The Hygicult TPC dipslide, contact plate, and swabbing methods gave similar results at all 3 microbial levels tested: 0.35–0.43 cfu/cm2 at the lowest level, 1.9–2.2 cfu/cm2 at the middle level, and 7.1–9.1 cfu/cm2 at the highest level.
Analysis of DDT Residues in Soil by ELISA: An International Interlaboratory Study
Authors: Maestroni Britt M , Skerritt John H , Ferris Ian G , Ambrus Arpad ,   Collaborators:, Amin R , Bajet N , Dagher S , Genhai Y , Ghanem I , Guo J , Hock B , Jebakumar S R D , Maestroni B , Maqbool U , Matthews W , Merino R , Montoya A , Mukherjee P K , Prapamontol T , Skerritt J , Stanker L , Takyi E , Yücel Ü 
Published: February 2020

Abstract
An international interlaboratory study was conducted to determine the performance of a group of laboratories from developing and developed countries. The study used a commercial microwell ELISA on unknown samples spiked with different levels of DDT. The study design was based on Youden pairs and balanced replicates. Two soils, differing in particle size distributions, organic matter content, and cation-exchange capacities and thought to be DDT-free, were spiked at 5 DDT levels between 0.025 and 2 mg/kg. Nineteen laboratories in 17 countries took part in the collaborative trial; of these, the majority were modestly equipped laboratories in developing countries. Samples were analyzed without filtration or cleanup and using standards of pure DDT in methanol. Data were analyzed for repeatability and reproducibility, and average recoveries at the spike levels were calculated. Mean real recoveries for both soils were similar (103% for soil A and 100% for soil B), with values between 0.1 and 2 mg/kg DDT. Precision estimates were best in the linear working range of the assay (0.1–0.5 mg/kg DDT), with reproducibility relative standard deviations (RSDR) typically averaging about 38 and 46% near the upper and lower detection limits, respectively. Corresponding repeatability relative standard deviation (RSDr) values were 20–36% and 36–57%. Thus, even though much of the trial was performed under developing country conditions, performance statistics were similar to other reported results obtained with ELISAs on small molecules of agricultural importance, such as mycotoxins and pesticide and antibiotic residues.
Immunoaffinity Column Cleanup with Liquid Chromatography for Determination of Aflatoxin M1 in Liquid Milk: Collaborative Study
Authors: Dragacci Sylviane , Grosso Frederic , Gilbert John ,   Collaborators:, Agnedal M , Hyndrick L , Jamet G , Jorgensen K , Miller J , Oliveira Palavras L , Pittet A , Rousi V , Sharron P , Sizoo E A , Spott M , Strassmeier E 
Published: February 2020

Abstract
A collaborative study was conducted to evaluate the effectiveness of an immunoaffinity column cleanup liquid chromatographic method for determination of aflatoxin M1 in milk at proposed European regulatory limits. The test portion of liquid milk was centrifuged, filtered, and applied to an immunoaffinity column. The column was washed with water, and aflatoxin was eluted with pure acetonitrile. Aflatoxin M1 was separated by reversed-phase liquid chromatography (LC) with fluorescence detection. Frozen liquid milk samples both naturally contaminated with aflatoxin M1 and blank samples for spiking, were sent to 12 collaborators in 12 different European countries. Test portions of samples were spiked at 0.05 ng aflatoxin M1 per mL. After removal of 2 noncompliant sets of results, the mean recovery of aflatoxin M1 was 74%. Based on results for spiked samples (blind pairs at 1 level) and naturally contaminated samples (blind pairs at 3 levels) the relative standard deviation for repeatability (RSDr) ranged from 8 to 18%. The relative standard deviation for reproducibility (RSDR) ranged from 21 to 31%. The method showed acceptable within- and between-laboratory precision data for liquid milk, as evidenced by HORRAT values at the low level of aflatoxin M1 contamination.
The relative controls of temperature and soil moisture on the start of carbon flux phenology and net ecosystem production in two alpine meadows on the Qinghai-Tibetan Plateau
Authors: Chai Xi , Shi Peili , Song Minghua , Zong Ning , He Yongtao , Li Yingnian , Zhang Xianzhou , Liu Yanjiao 
Published: February 2020

Abstract

Aims
Variations in vegetation spring phenology are widely attributed to temperature in temperate and cold regions. However, temperature effect on phenology remains elusive in cold and arid/semiarid ecosystems because soil water condition also plays an important role in mediating phenology.

Methods
We used growing degree day (GDD) model and growing season index (GSI) model, coupling minimum temperature (Tmin) with soil moisture (SM) to explore the influence of heat requirement and hydroclimatic interaction on the start of carbon uptake period (SCUP) and net ecosystem productivity (NEP) in two alpine meadows with different precipitation regimes on the Qinghai-Tibet Plateau (QTP). One is the water-limited alpine steppe-meadow, and the other is the temperature-limited alpine shrub-meadow.

Important Findings
We observed two clear patterns linking GDD and GSI to SCUP: SCUP was similarly sensitive to variations in preseason GDD and GSI in the humid alpine shrub-meadow, while SCUP was more sensitive to the variability in preseason GSI than GDD in the semiarid alpine steppe-meadow. The divergent patterns indicated a balance of the limiting climatic factors between temperature and water availability. In the humid meadow, higher temperature sensitivity of SCUP could maximize thermal benefit without drought stress, as evidenced by the stronger linear correlation coefficient (R2) and Akaike’s information criterion (AIC) between observed SCUPs and those of simulated by GDD model. However, greater water sensitivity of SCUP could maximize the benefit of water in semiarid steppe-meadow, which is indicated by the stronger R2 and AIC between observed SCUPs and those of simulated by GSI model. Additionally, although SCUPs were determined by GDD in the alpine shrub-meadow ecosystem, NEP was both controlled by accumulative GSI in two alpine meadows. Our study highlights the impacts of hydroclimatic interaction on spring carbon flux phenology and vegetation productivity in the humid and semiarid alpine ecosystems. The results also suggest that water, together with temperature should be included in the models of phenology and carbon budget for alpine ecosystems in semiarid regions. These ﬁndings have important implications for improving vegetation phenology models, thus advancing our understanding of the interplay between vegetation phenology, productivity and climate change in future.
Self-gravity in magnetized accretion discs as a result of a dynamo mechanism with outflows
Authors: Karimzadeh S , Khesali A R , Khosravi A 
Published: February 2020

ABSTRACT
We investigate the stationary model of a geometrically thin, magnetized accretion disc, which has a dipole-symmetry magnetic field that is produced by an α−ω dynamo and can emanate winds from the disc’s surfaces. Although self-gravity has an important role in the evolution of astrophysical systems, it has been disregarded in many cases, because the equations become more complicated when the mass distribution of the disc is included in the total gravitational potential. In this paper, we consider the effects of self-gravity on the above-mentioned model. It is shown that in the presence of vertical self-gravity, while the magnetic diffusivity decreases, the magnetic field bends and the inflow speed increases. Also, in the inner parts of the disc, mass flux resulting from the wind has a positive value compared with the non-self-gravitating solution, in which all accreted materials are lost. These results can be used for the discs of active galactic nuclei, in which self-gravity is only important in the vertical direction. However, for other types, such as the discs surrounding young stellar objects, self-gravity can be considered in both vertical and radial directions. Here, our analysis of fully self-gravitating discs has revealed that, in this case, the inflow speed depends on the radius. In the model we study, it is also found that the outflows have no effective contribution to the removal of angular momentum for certain radii r ≥ 6R, as is &gt; 60°. However, the system cannot be stabilized by viscous dissipation.
Long-term NIR variability in the UKIDSS Ultra Deep Survey: a new probe of AGN activity at high redshift
Authors: Elmer E , Almaini O , Merrifield M , Hartley W G , Maltby D T , Lawrence A , Botti I , Hirst P 
Published: February 2020

ABSTRACT
We present the first attempt to select active galactic nuclei (AGN) using long-term near-infrared (NIR) variability. By analysing the K-band light curves of all the galaxies in the UKIRT Infrared Deep Sky Survey (UKIDSS) Ultra Deep Survey, the deepest NIR survey over ∼1 deg2, we have isolated 393 variable AGN candidates. A comparison to other selection techniques shows that only half of the variable sources are also selected using either deep Chandra X-ray imaging or Infrared Array Camera (IRAC) colour selection, suggesting that using NIR variability can locate AGN that are missed by more standard selection techniques. In particular, we find that long-term NIR variability identifies AGN at low luminosities and in host galaxies with low stellar masses, many of which appear relatively X-ray quiet.
Spectroscopy of hot γ Doradus and A–F hybrid Kepler candidates close to the hot border of the δ Scuti instability strip
Authors: Kahraman Aliçavuş F , Poretti E , Catanzaro G , Smalley B , Niemczura E , Rainer M , Handler G 
Published: February 2020

ABSTRACT
If γ Dor-type pulsations are driven by the convective blocking mechanism, a convective envelope at a sufficient depth is essential. There are several hot γ Dor and hybrid star candidates in which there should not be an adequate convective envelope to excite the γ Dor-type oscillations. The existence of these hot objects needs an explanation. Therefore, we selected, observed, and studied 24 hot γ Dor and hybrid candidates to investigate their properties. The atmospheric parameters, chemical abundances, and vsin i values of the candidates were obtained using medium-resolution (R  =  46 000) spectra taken with the Fibre-fed Échelle Spectrograph instrument mounted at the Nordic Optical Telescope. We also carried out frequency analyses of the Kepler long- and short-cadence data to determine the exact pulsation contents. We found only five bona fide hot γ Dor and three bona fide hot hybrid stars in our sample. The other 16 stars were found to be normal γ Dor, δ Sct, or hybrid variables. No chemical peculiarity was detected in the spectra of the bona fide hot γ Dor and hybrid stars. We investigated the interplay between rotation and pulsational modes. We also found that the hot γ Dor stars have higher Gaia luminosities and larger radii compared to main-sequence A–F stars.
On the wave optics effect on primordial black hole constraints from optical microlensing search
Authors: Sugiyama Sunao , Kurita Toshiki , Takada Masahiro 
Published: February 2020

ABSTRACT
Microlensing of stars, e.g. in the Galactic bulge and Andromeda galaxy (M31), is among the most robust, powerful method to constrain primordial black holes (PBHs) that are a viable candidate of dark matter. If PBHs are in the mass range $M_{\rm PBH} {\,\,\lesssim \,\,}10^{-10}\mathrm{ M}_\odot$, its Schwarzschild radius (rSch) becomes comparable with or shorter than optical wavelength (λ) used in a microlensing search, and in this regime the wave optics effect on microlensing needs to be taken into account. For a lensing PBH with mass satisfying rSch ∼ λ, it causes a characteristic oscillatory feature in the microlensing light curve, and it will give a smoking gun evidence of PBH if detected, because any astrophysical object cannot have such a tiny Schwarzschild radius. Even in a statistical study, e.g. constraining the abundance of PBHs from a systematic search of microlensing events for a sample of many source stars, the wave effect needs to be taken into account. We examine the impact of wave effect on the PBH constraints obtained from the r-band (6210 Å) monitoring observation of M31 stars in Niikura et al., and find that a finite source size effect is dominant over the wave effect for PBHs in the mass range MPBH ≃ [10−11, 10−10]M⊙. We also discuss that, if a denser cadence (10 s), g-band monitoring observation for a sample of white dwarfs over a year time-scale is available, it would allow one to explore the wave optics effect on microlensing light curve, if it occurs, or improve the PBH constraints in $M_{\rm PBH} {\,\,\lesssim \,\,}10^{-11}\mathrm{ M}_\odot$ even from a null detection.