bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring Frequency-Dependent Brain Networks from Ongoing EEG Using Spatial ICA During Music Listening
Authors: Zhu Yongjie , Zhang Chi , Poikonen Hanna , Toiviainen Petri , Huotilainen Minna , Mathiak Klaus , Ristaniemi Tapani , Cong Fengyu 
Published: March 2020

AbstractRecently, exploring brain activity based on functional networks during naturalistic stimuli especially music and video represents an attractive challenge because of the low signal-to-noise ratio in collected brain data. Although most efforts focusing on exploring the listening brain have been made through functional magnetic resonance imaging (fMRI), sensor-level electro- or magnetoencephalography (EEG/MEG) technique, little is known about how neural rhythms are involved in the brain network activity under naturalistic stimuli. This study exploited cortical oscillations through analysis of ongoing EEG and musical feature during freely listening to music. We used a data-driven method that combined music information retrieval with spatial Fourier Independent Components Analysis (spatial Fourier–ICA) to probe the interplay between the spatial profiles and the spectral patterns of the brain network emerging from music listening. Correlation analysis was performed between time courses of brain networks extracted from EEG data and musical feature time series extracted from music stimuli to derive the musical feature related oscillatory patterns in the listening brain. We found brain networks of musical feature processing were frequency-dependent. Musical feature time series, especially fluctuation centroid and key feature, were associated with an increased beta activation in the bilateral superior temporal gyrus. An increased alpha oscillation in the bilateral occipital cortex emerged during music listening, which was consistent with alpha functional suppression hypothesis in task-irrelevant regions. We also observed an increased delta–beta oscillatory activity in the prefrontal cortex associated with musical feature processing. In addition to these findings, the proposed method seems valuable for characterizing the large-scale frequency-dependent brain activity engaged in musical feature processing.
PERK-eIF2α-ATF4 signaling contributes to osteogenic differentiation of periodontal ligament stem cells
Authors: Yang Shuangyan , Hu Lihua , Wang Chunling , Wei Fulan 
Published: March 2020

AbstractProtein kinase-like endoplasmic reticulum kinase (PERK) is a type I transmembrane protein located in the endoplasmic reticulum (ER). The PERK-eukaryotic initiation factor 2α (eIF2α)-activating transcription factor 4 (ATF4) pathway has been proved to be involved in osteoblast differentiation, but the involvement of the PERK-eIF2α-ATF4 signaling pathway in osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) has remained unclear. Therefore, the aim of this study was to explore the role of PERK in osteogenic differentiation of hPDLSCs and to assess whether PERK-eIF2α-ATF4 contributes to the process of osteogenic differentiation in hPDLSCs. In our study, we constructed PERK-overexpressed and PERK-silenced hPDLSCs by lentiviral transduction. Furthermore, lentivirus-transfected cells were induced to differentiate into osteoblast cells for different days. Alkaline phosphatase (ALP) activity and Alizarin Red staining were used to evaluate the mineralization capacity, and the expression levels of related genes-ATF4, ALP, bone sialoprotein, runt-related transcription factor 2 (Runx2), and osteocalcin were measured to evaluate the osteogenic differentiation of hPDLSCs. The results showed that over-expression of PERK greatly increased ALP activity and the expression levels of related osteogenic genes, which displayed the strongest osteogenesis capacity. However, suppression of PERK caused decreased ALP activity and the weakest osteogenesis capacity, and the levels of ATF4 and p-eIF2α in PERK-silenced hPDLSCs were also decreased. Our results indicated that the PERK gene plays an important role in the differentiation of hPDLSCs to osteoblast-like cells. The PERK-eIF2α-ATF4 signaling pathway contributes to osteoblast differentiation of hPDLSCs.
Expression and Circulating Levels of Perlecan in Breast Cancer - Implications for Oestrogen Dependent Stromal Remodeling
Authors: Jansson Malin , Billing Ola , Herdenberg Carl , Lundin Christina , Tolockiene Egle , Nazemroaya Anoosheh , Sund Malin 
Published: March 2020

AbstractLocalised breast cancer can be cured by surgery and adjuvant treatments, but mortality remains high as some tumours metastasize early. Perlecan is a basement membrane (BM) protein involved in tumour development and progression. Here, mRNA and protein expression of perlecan, and mRNA expression of matrix degrading enzymes were studied in normal breast and invasive breast cancer, and correlated to prognostic risk factors, in particular oestrogen status. Moreover, plasma levels of perlecan were measured in patients with breast cancer and compared with controls. mRNA data was extracted from the Cancer Genome Atlas database. Perlecan protein expression was visualized using immunofluorescence and plasma levels measured by ELISA assay. Perlecan mRNA levels were twice as high in normal breast compared with breast cancer tissue. A strong correlation was found between mRNA expression of perlecan and several matrix-degrading enzymes in oestrogen receptor positive (ER+) tumours. Perlecan protein was localized to both epithelial and vascular BMs, but absent in the stroma in normal breast. In breast cancer, the expression of perlecan in epithelial BM was fragmented or completely lost, with a marked upregulation of perlecan expression in the stroma. Significantly higher levels of perlecan were found in plasma of ER+ patients when compared with ER- patients. This study shows that perlecan expression and degradation in breast cancer may be linked to the ER status of the tumour.
Rational requirements for suspended judgment
Authors: Rosa Luis 
Published: March 2020

AbstractHow does rationality bind the agnostic, that is, the one who suspends judgment about whether a given proposition is true? In this paper I explore two alternative ways of establishing what the rational requirements of agnosticism are: the Lockean–Bayesian framework and the doxastic logic framework. Each of these proposals faces strong objections. Fortunately, however, there is a rich kernel of requirements of agnosticism that are vindicated by both of them. One can then endorse the requirements that belong to that kernel without thereby committing oneself to the problematic implications that stem from either of the aforementioned proposals.
unarXive: a large scholarly data set with publications’ full-text, annotated in-text citations, and links to metadata
Authors: Saier Tarek , Färber Michael 
Published: March 2020

AbstractIn recent years, scholarly data sets have been used for various purposes, such as paper recommendation, citation recommendation, citation context analysis, and citation context-based document summarization. The evaluation of approaches to such tasks and their applicability in real-world scenarios heavily depend on the used data set. However, existing scholarly data sets are limited in several regards. In this paper, we propose a new data set based on all publications from all scientific disciplines available on arXiv.org. Apart from providing the papers’ plain text, in-text citations were annotated via global identifiers. Furthermore, citing and cited publications were linked to the Microsoft Academic Graph, providing access to rich metadata. Our data set consists of over one million documents and 29.2 million citation contexts. The data set, which is made freely available for research purposes, not only can enhance the future evaluation of research paper-based and citation context-based approaches, but also serve as a basis for new ways to analyze in-text citations, as we show prototypically in this article.
Die Einführung der Kennzeichnungspflicht für Polizeibeamte: Ein QCA-basierter Bundesländervergleich
Authors: Bandau Frank , Bothner Fabio 
Published: March 2020

ZusammenfassungWiederholte Vorfälle von Polizeigewalt bei Demonstrationen haben in Deutschland zu Forderungen nach einer individuellen Kennzeichnung von Polizeibeamten bei derartigen Einsätzen geführt. In der Folge hat ein Teil der Bundesländer eine nummerische Kennzeichnung eingeführt, während dies in anderen Bundesländern bisher nicht geschehen ist. Der Artikel geht der Frage nach, wie diese Varianz zwischen den Ländern zu erklären ist, und ermittelt, unter welchen Bedingungen es zur Einführung der Kennzeichnungspflicht kommt. Eine crisp-set Qualitative Comparative Analysis (csQCA) dient dabei der Identifizierung von Konfigurationen von Erklärungsfaktoren, die zur Einführung der Kennzeichnung von Polizisten führen. Ergänzt wird die QCA um kurze Fallstudien (Berlin, Hessen, Mecklenburg-Vorpommern, Rheinland-Pfalz und Schleswig-Holstein), die dazu dienen, die zuvor proklamierten Kausalmechanismen zu überprüfen. Basierend auf diesem methodischen Vorgehen gelangt die Studie zu dem Ergebnis, dass die Regierungsbeteiligung von Grünen oder Linken als Agenda-Setter eine notwendige Bedingung für die Einführung der Kennzeichnung darstellt. Darüber hinaus zeigt sich, dass das Auftreten eines Agenda-Setters bei gleichzeitigem Fehlen eines Blockierers in Form von CDU/CSU eine günstige Regierungskonstellation für die Kennzeichnungspflicht darstellt. Damit es tatsächlich zur Einführung kommt, müssen aber entsprechende Rahmenbedingungen herrschen. Beim Vorreiter Berlin war dies durch das Auftreten eines Focusing Events der Fall, bei den Nachzüglern begünstigte der resultierende Diffusionsdruck die Durchsetzung der Kennzeichnungspflicht.
Virucidal Efficacy of Olanexidine Gluconate as a Hand Antiseptic Against Human Norovirus
Authors: Imai Kaoru , Hagi Akifumi , Inoue Yasuhide , Amarasiri Mohan , Sano Daisuke 
Published: March 2020

AbstractHuman noroviruses are the major cause of non-bacterial acute gastroenteritis worldwide. Since no therapeutic agent has been proven to prevent human norovirus infection yet, preventive healthcare interventions to block the infection routes play an important role in infection control. One of the possible infection routes of human noroviruses are through contaminated hands, but no hand antiseptics have been proven effective. Olanexidine gluconate is a new biguanide compound that has already been approved for sale as an antiseptic for the surgical field in Japan. A new hand antiseptic was developed using olanexidine gluconate in this study, and its virucidal efficacy against human noroviruses was evaluated using modified RT-qPCR that can account for genome derived from intact viruses using RNase A and photo-reactive intercalators. We tested the virucidal efficacy of five materials; two olanexidine gluconate antiseptics (hand rub formulation and surgical field formulation), two kinds of ethanol solutions at different pH (approx. 3 or 7), and a base component of olanexidine gluconate hand rub formulation against 11 human norovirus genotypes by culture-independent methods. The infectivity of murine norovirus (MNV), a surrogate for human norovirus, was significantly reduced after use of the antiseptics. The olanexidine gluconate hand rub demonstrated the strongest virucidal efficacy against human norovirus among the five tested materials. This study showed that olanexidine gluconate has the potential to become a strong tool for the prevention of human norovirus infection.
Utilization of Municipal Plastic and Wood Waste in Industrial Manufacturing of Wood Plastic Composites
Authors: Basalp Dildare , Tihminlioglu Funda , Sofuoglu Sait C. , Inal Fikret , Sofuoglu Aysun 
Published: March 2020

Abstract
In this study, Wood Plastic Composites (WPCs) were produced from post-consumer bulky wastes of recycled plastic and wood in order to minimize waste, decrease environmental effects of plastics, reserve natural resources, and support circular economy for sustainable production and consumption. Five different types of polypropylene (PP) or polyethylene (PE) based recycled plastics and wood obtained from urban household bulky wastes were used in the production of recycled WPC composites, r-WPCs. Virgin WPC (v-WPC) and r-WPC compounds were prepared with wood flour (WF) and maleic anhydride grafted compatibilizer (MAPP or MAPE) to evaluate the effect of recycled polymer type and compatibilizer on the mechanical properties. It was found that tensile strength properties of r-WPCs produced from recycled PP (r-PP) were higher than that of the r-WPCs produced from mixed polyolefins and recycled PE. r-WPCs containing anti-oxidants, UV stabilizers, and compatibilizer with different WF compositions were produced from only recycled garden fraction PP (PPFGF) to determine the optimum composition and processing temperature for pilot scale manufacturing of r-WPCs. Based on tensile, impact, flexural, and water sorption properties of r-WPC compounds with different formulations, the optimum conditions of r-WPC compounds for industrial manufacturing process were determined. Surface morphology of fractured surfaces as well as tensile, flexural and density results of r-WPC compounds revealed the enhancement effect of MAPP on interfacial adhesion in r-WPCs. r-WPC products (crates and table/chair legs) based on bulky wastes were produced using an injection molding process at industrial scale by using 30 wt% WF-filled r-WPC compound. This study demonstrated that r-WPC compounds from recycled bulky plastic and wood wastes can be used as a potential raw material in plastic as well as WPC industry, contributing to circular economy.

Graphic Abstract
Assessment of agricultural potential of a river command using geo-spatial techniques: a case study of Himalayan river project in Northern India
Authors: Akhtar M. P. , Roy L. B. , Vishwakarma K. M. 
Published: March 2020

AbstractAgriculture and associated sectors are one of the primary sources of living for the global population. Sustainability in agriculture will yield long-term benefits requisite to accomplish development and mitigation of resource scarcity. Hence, realistic assessment of water requirement for agricultural use or alternatively agricultural potential from available water resources is imperative to sustainable water management keeping in view of possible scarce situation in relation to freshwater availability across the Globe. The present study focuses on assessment of the water requirement for potential agricultural use for the command area of a Himalayan river project, namely Gandak river project in Northern India using extensive geo-spatial techniques. Detailed information of extensive canal network is derived from high-resolution satellite images using GIS tools, along with other spatially distributed information for relevant parameters such as rainfall, temperature, soil type, elevation, water-holding capacity and agricultural productivity. The study reasonably identifies the spatial variability in water requirement potential in the project command with rational indication of maximum water demand in north-central section of the study area where the lowest aridity index characterized by very low slope and deep sandy loam soil is recorded. Efficient usage with growing scarcity of this essential natural resource warrants efficiency optimization of water usage with realistic assessment. This approach unlike traditional method uses high-resolution satellite data that are more scientific and accurate and will undoubtedly facilitate development of rational decision support system for efficient management of available surface water use for different purposes in the region.
Exponential finite difference methods for solving Newell–Whitehead–Segel equation
Authors: Hilal Nayrouz , Injrou Sami , Karroum Ramez 
Published: March 2020

AbstractThis work presents two different finite difference methods to compute the numerical solutions for Newell–Whitehead–Segel partial differential equation, which are implicit exponential finite difference method and fully implicit exponential finite difference method. Implicit exponential methods lead to nonlinear systems. Newton method is used to solve the resulting systems. Stability and consistency are discussed. To illustrate the accuracy of the proposed numerical methods, some examples are delivered at the end.
Insecticide resistance management against thrips (Thysanoptera: Thripidae) on onion in the central Rift Valley of Ethiopia
Authors: Negash Belete , Azerefegn Ferdu , Ayalew Gashawbeza 
Published: March 2020

AbstractTwo field experiments were conducted in the Central Rift Valley of Ethiopia in the hot and cool dry seasons of 2016/2017 with the objective to develop an insecticide resistance management program on thrips infesting onion. The first experiment dealt with the evaluation of four different insecticides namely profenofos, λ–cyhalothrin, imidacloprid, and spinetoram in different sequences on thrips population and their effect on yield. The second experiment examined the effect of admixing the surfactant organosilicone with imidacloprid, spinetoram and dimethoate. A Randomized Complete Block Design with three replications was used for both experiments. Data on number of thrips, bulb yield and economic returns were collected. The insecticide imidacloprid and spinetoram resulted in fewer numbers of thrips and higher yields than profenofos and λ –cyhalothrin. Application of the more effective insecticides when the thrips population was high followed by less effective insecticides resulted in better control and higher economic return. Surfactant added insecticides gave a fewer numbers of thrips and higher yields than the corresponding insecticides applied without surfactant. The sequential application of spinetoram and imidacloprid with less effective λ-cyhalothrin and profenofos by mixing with adjuvant are recommended for thrips control as an integral component of thrips management in the Central Rift Valley of Ethiopia.
Acute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor–receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels
Authors: Romero-Fernandez Wilber , Zhou Zilong , Beggiato Sarah , Wydra Karolina , Filip Malgorzata , Tanganelli Sergio , Borroto-Escuela Dasiel O. , Ferraro Luca , Fuxe Kjell 
Published: March 2020

AbstractBackgroundAntagonistic adenosine A2A receptor (A2AR)-dopamine D2 receptor (D2R) receptor–receptor interactions have previously been demonstrated in A2AR–D2R heteroreceptor complexes in the rat dorsal striatum. They mainly involve a reduction of affinity in the high-affinity component of the D2R agonist binding site upon activation in vivo of the A2AR by an A2AR agonist. Upon cocaine self-administration, this antagonistic A2AR–D2R interaction disappeared in the dorsal striatum.MethodsIn the current experiments, it was tested whether such modifications in the antagonistic A2AR–D2R receptor–receptor interactions can develop also after an acute systemic injection of a low cocaine dose (1 mg/kg; sc).ResultsMicrodialysis experiments indicated that acute cocaine did not significantly alter the extracellular dopamine levels in the dorsal striatum of the awake Wistar rats. Competition dopamine receptor binding experiments demonstrated that in the acute cocaine group, the A2AR agonist CGS-21680 produced significantly larger increases in the D2RKi, Highvalues (reduction of high-affinity) versus the saline-injected (i.e. control) group. Furthermore, in the dorsal striatum membrane preparation from acute cocaine-injected rats, CGS-21680 also produced significant increases in the D2RKi, Lowvalues (reduction of low-affinity) and in the proportion of D2Rs in the high-affinity state (RH). Such significant effects were not observed with CGS-21680 in the control group.ConclusionsThe molecular mechanism involved in the acute cocaine-induced increase in the antagonistic allosteric A2AR–D2R receptor–receptor interactions may be an increased formation of higher-order complexes A2AR–D2R-sigma1R in which cocaine by binding to the sigma1R protomer also allosterically enhances the inhibitory A2AR–D2R interaction in this receptor complex.
Coniferous woods from the Upper Triassic of southwestern Gondwana, Tronquimalal Group, Neuquén Basin, Mendoza Province, Argentina
Authors: Gnaedinger Silvia C. , Zavattieri Ana María 
Published: March 2020

AbstractLate Triassic coniferous species of silicified woods are described from the Tronquimalal Group, Llantenes Depocenter of the Neuquén Basin, southern Mendoza Province, Argentina. The new speciesAgathoxylon cozzoiandAgathoxylon lamaibandianusCrisafulli and Herbst, 2011 described in this study were found in proximal volcaniclastic facies deposited in alluvial fans and proximal braided river plains of the Chihuido Formation, which is the basal unit of the Group. The speciesA.lamaibandianusCrisafulli and Herbst,Protojuniperoxylon ischigualastense(Bonetti, 1966) Bodnar and Artabe, 2007, and the new speciesCupressinoxylon llantenesensealso described in this study were collected from the upper fluvio-deltaic plain and delta-plain deposits that prograded into a large, meromictic and wedge-shaped lake of the overlying Llantenes Formation. The Tronquimalal Group yields abundant and well-known Triassic plant remains of the Southern Gondwana “DicroidiumFlora,” although it also contains typical early Jurassic taxa displaying age affinities with other Argentinean “Florian Stage” communities of Late Triassic (Norian–?Rhaetian). The lignotaxa described from both units of the Tronquimalal Group may all together represent coniferous forests of the extratropical area of the Southwestern Province of Gondwana. Deciduous conifer forests associated with herbaceous and shrub communities dominated by ferns and smaller corystosperms, and other taxa including theLinguifoliumleaves within the Llantenes Depocenter environments, were developed on the western margin of the continent under seasonal temperate-warm and humid to sub-humid climate with a marine influence from the west.
Iconicity in American Sign Language–English translation recognition
Authors: ANIBLE BENJAMIN 
Published: March 2020

abstractReaction times for a translation recognition study are reported where novice to expert English–ASL bilinguals rejected English translation distractors for ASL signs that were related to the correct translations through phonology, semantics, or both form and meaning (diagrammatic iconicity). Imageability ratings of concepts impacted performance in all conditions; when imageability was high, participants showed interference for phonologically related distractors, and when imageability was low participants showed interference for semantically related distractors, regardless of proficiency. For diagrammatically related distractors high imageability caused interference in experts, but low imageability caused interference in novices. These patterns suggest that imageability and diagrammaticity interact with proficiency – experts process diagrammatic related distractors phonologically, but novices process them semantically. This implies that motivated signs are dependent on the entrenchment of language systematicity; rather than decreasing their impact on language processing as proficiency grows, they build on the original benefit conferred by iconic mappings.