bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Inhaled Iloprost on Lung Mechanics and Myocardial Function During One-Lung Ventilation in Chronic Obstructive Pulmonary Disease Patients Combined With Poor Lung Oxygenation
Authors: Kim Namo , Lee Su Hyun , Joe Youngeun , Kim Taelim , Shin Heesoo , Oh Young Jun 
Published: March 2020

BACKGROUND:
The ventilation/perfusion mismatch in chronic obstructive pulmonary disease (COPD) patients can exacerbate cardiac function as well as pulmonary oxygenation. We hypothesized that inhaled iloprost can ameliorate pulmonary oxygenation with lung mechanics and myocardial function during one-lung ventilation (OLV) in COPD patients combined with poor lung oxygenation.

METHODS:
A total of 40 patients with moderate to severe COPD, who exhibited the ratio of partial pressure of arterial oxygen to the fraction of inspired oxygen (Pao
2/Fio
2) <150 mm Hg 30 minutes after initiating OLV, were enrolled in this study. Patients were randomly allocated into either ILO group (n = 20) or Control group (n = 20), in which iloprost (20 μg) and saline were inhaled, respectively. The Pao
2/Fio
2 ratio, dead space, dynamic compliance, and tissue Doppler imaging with myocardial performance index (MPI) were assessed 30 minutes after initiating OLV (pre-Tx) and 30 minutes after completion of drug inhalation (post-Tx). Repeated variables were analyzed using a linear mixed-model between the groups.

RESULTS:
At pre-Tx, no differences were observed in measured parameters between the groups. At post-Tx, Pao
2/Fio
2 ratio (P < .001) and dynamic compliance (P = .023) were significantly higher and dead space ventilation was significantly lower (P = .001) in iloprost group (ILO group) compared to Control group. Left (P = .003) and right ventricular MPIs (P < .001) significantly decreased in ILO group compared to Control group.

CONCLUSIONS:
Inhaled iloprost improved pulmonary oxygenation, lung mechanics, and cardiac function simultaneously during OLV in COPD patients with poor lung oxygenation.
Coordination Behaviors of Diphenylketene Adsorbed in the Nanocages of Zeolite NaY and AgY
Authors: Shibata Shintaro , Masui Yoichi , Onaka Makoto 
Published: March 2020

Abstract
We investigated in detail how polar cumulene molecules like diphenylketene were accommodated in faujasite zeolite pores based on 13C CP/MAS and DD/MAS NMR analyses as well as quantum chemical calculations after adsorbing the molecule into the zeolite NaY or AgY having “hard” sodium ions or “soft” silver ions. Since the diphenylketene has such a specific structure that a carbonyl group (a hard base) is accumulated by a carbon-carbon double bond (a soft π base), which is conjugated with two benzene rings (soft π bases), it is possible for the diphenylketene to adopt multicoordination modes to different metal ions in the zeolite. Compared with the coordination modes of benzophenone and 1,1-diphenylethene adsorbed in the NaY and AgY, those of diphenylketene were identified, and specific coordination behaviors in the zeolite’s supercages were classified depending on the hard or soft metal characters: The C=O and phenyl coordination modes to Na+ in NaY prevail, while the C=C and phenyl coordination to Ag+ in AgY is favored. We also unveiled the difference in the molecular mobility depending on the types of cations in the zeolite by comparing the 13C CP/MAS and DD/MAS NMR spectra.
Effectiveness and cost-effectiveness of out-of-hours palliative care: a systematic review
Authors: Johnston Bridget M. , McCauley Rachel , McQuillan Regina , Rabbitte Mary , Honohan Caitriona , Mockler David , Thomas Steve , May Peter 
Published: March 2020

Background: Out-of-hours palliative care is a priority for patients, caregivers and policymakers. Approximately three quarters of the week occurs outside of typical working hours, and the need for support in care of serious and terminal illness during these times is commonplace. Evidence on relevant interventions is unclear. Aim: To review systematically the evidence on the effect of out-of-hours specialist or generalist palliative care for adults on patient and caregiver outcomes, and costs and cost-effectiveness. Methods: A systematic review of peer-reviewed and grey literature was conducted. We searched Embase, MEDLINE [Ovid], Cochrane Library, CINAHL, Allied and Complementary Medicine [Ovid], PsycINFO, Web of Science, Scopus, EconLit (Ovid), and grey literature published between 1 January 2000 and 12th November 2019. Studies that comparatively evaluated the effect of out-of-hours specialist or generalist palliative care for adults on patient and caregiver outcomes, and on costs and cost-effectiveness were eligible, irrespective of design. Only English-language studies were eligible. Two reviewers independently examined the returned studies at each stage (title and abstract review, full-text review, and quality assessment). Results: We identified one eligible peer-reviewed study, judged as insufficient quality. Other sources returned no eligible material. The systematic review therefore included no studies. Conclusions: The importance of integrated, 24-hour care for people in line with a palliative care approach is not reflected in the literature, which lacks evidence on the effects of interventions provided outside typical working hours. Registration: PROSPERO CRD42018111041.
Recensão ao Livro Escola pública. Tempos difíceis, mas não impossíveis
Authors: Damião Maria Helena 
Published: March 2020

Krawczyk, Nora (Org.) (2018). Escola pública. Tempos difíceis, mas não impossíveis. Campinas: Faculdade de Educação da Universidade Estadual de Campinas.
“Escola pública. Tempos difíceis, mas não impossíveis” é o título de um livro publicado em finais de 2018 com a chancela da Faculdade de Educação da Universidade Estadual de Campinas. Apresentando, em subtítulo, um diagnóstico preocupante da escola estatal, abre, em simultâneo, portas à sua superação. Esta é a linha de reflexão, predominantemente sociológica, que dá coerência à obra.
Resultando de um congresso internacional, com o mesmo título, realizado em 2017, aquando das comemorações dos quarenta e cinco anos dessa Faculdade, detêm-se no contexto educativo brasileiro, que, à semelhança de muitos outros, segue, de maneira próxima, a ideia de educação que se afirma como global. Organizado por uma professora da Faculdade (Nora Krawczyk), que escreveu a Introdução, tem Prefácio das suas Diretora e Diretora Associada (Dirce Zan e Débora Mazza). São duas partes que, apesar de breves, traduzem um compromisso claro e, devemos reconhecer, corajoso, para com a escola pública, o qual se vê replicado nos vários textos.
(...)
PPIs and GI Cancers: Impeached But Likely to Be Acquitted
Authors: Howden Colin W. 
Published: March 2020

Abstract
In this edition of the journal, there is an important nested case-control study from investigators at Kaiser Permanente, Northern California. Proton pump inhibitor exposure for 10 or more years was not associated with any increased risk of gastric cancer. Small observed increased risks of colorectal, hepatocellular, and pancreatic cancers with 10 or more years of exposure are likely to have been spurious. If proton pump inhibitors were to be impeached on the basis of gastrointestinal cancer risk, they are likely to be subsequently acquitted.
Koagulasi Pewarna Indigo Karmina (Disodium-3,3’-dioxo-2,2’-bi-indolylidene-5,5’-disulfonat) dengan Metode Elektrolisis Menggunakan Anoda Seng
Authors: Darmawan Adi , Suhartana Suhartana , Kristinawati Leny 
Published: March 2020

Zat warna indigo karmina merupakan salah satu senyawa organik yang digunakan dalam proses pewarnaan tekstil. Zat warna ini menghasilkan limbah cair yang mengakibatkan pencemaran dan kerusakan lingkungan. Sementara seng sisa juga mudah ditemukan. Elektrolisis merupakan suatu metode yang digunakan untuk memanfaatkan kembali kedua limbah tersebut. Logam seng dimanfaatkan sebagai elektroda untuk mendekolorisasi pewarna indigo karmina. Elektrolisis dilakukan selama 7 menit dan tegangan eksternal 6 Volt dengan variasi pH dan temperatur. Hasil elektrolisis dianalisis dengan Spektrofotometer UV-Vis. Hasil penelitian menunjukkan bahwa elektrodekolorisasi dipengaruhi oleh pH dan temperatur. Elektrodekolorisasi pewarna indigo karmina efektif dilakukan pada pH asam yaitu 4 dengan persen dekolorisasi 94,52% dan pada temperatur 70oC dengan persen dekolorisasi 98,09 %.
Amobilasasi Biomassa Chlorella Sp pada Silika Gel sebagai Adsorben Tembaga
Authors: Hastuti Rum , Gunawan Gunawan 
Published: March 2020

Amobilisasi Biomassa Chlorella sp pada Silika gel sebagai adsorben, merupakan salah satu upaya untuk meningkatan kapasitas adsorpsi adsorben . Silika gel dan Biomassa Chlorella sp keduanya merupakan adsorben yang mempunyai keterbatasan kemampuan adsorpsin. Dengan melakukan amobilsasi Biomassa Chlorella sp pada silica gel diharapkan kesinergian sebagai adsorben dapat meningkatkan kapasitas adsorpsi adsorben tersebut. Uji kapasitas adsorpsi diterapkan pada larutan tembaga (II) melalui beberapa parameter perlakuan, yaitu pH larutan, waktu kontak dan konsentrasi larutan tembaga (II). Dari hasil pengamatan diperoleh peningkatan kapasitas adsorpsi 5 kali lebih besar. Kapasitas adsorpsi maksimal adsorben biomassa chlorella sp teramobilisasi terjadi pada pH=5 dengan kapasitas adsorpsi 24,91 mg/g, sedangkan kapasitas adsorpsi maksimal biomassa chlorella sp tanpa amobilisasi pada silica gel hanya 23,58 mg/g. pada pH=4
Daya Pemacu Pertumbuhan Monosodium Glutamat dan Efek Sampingnya pada Ren Ayam (Gallus sp)
Authors: Muliani Hirawati 
Published: March 2020

Penelitian ini bertujuan untuk mengetahui pengaruh monosodium glutamat terhadap pertumbuhan ayam petelur betina dan untuk mengetahui efek sampingnya terhadap ren. Dua puluh empat ekor ayam petelur betina diaklimasi selama 3 minggu. Ayam-ayam tersebut kemudian dikelompokkan menjadi 4 kelompok perlakuan, dengan 6 ulangan dalam tiap kelompok. Perlakuan yang diberikan adalah 0 mg; 7,5 mg; 15 mg; 22,5 mg monosodium glutamat per oral sekali sehari selama 3 minggu. Parameter utama yang diamati adalah pertambahan bobot badan, tinggi sel epitelium tubulus kontortus proksimalis, tinggi sel epitelium tubulus kontortus distalis, dan perubahan struktur glomerulus. Parameter penunjang yang diamati adalah berat ren pada akhir perlakuan. Data kuantitatif yang didapat dianalisis dengan analisis varians dengan Rancangan Acak Lengkap dan Uji Beda Nyata Terkecil. Hasil yang didapat menunjukkan bahwa monosodium glutamat dapat memacu pertumbuhan ayam petelur betina tetapi menyebabkan efek samping terjadinya glomerulonefritis pada ren.
Serum FGF-21 and FGF-23 in association with gestational diabetes: a longitudinal case-control study
Authors: Mosavat Maryam , Omar Siti Zawiah , Sthanshewar Pavai 
Published: March 2020

Abstract

Background
Fibroblast growth factors (FGFs); FGF-21 and FGF-23, have been proposed to be associated with metabolic syndrome. However, data on the role of these peptides in gestational diabetes mellitus (GDM) are limited. Therefore, this study was designed to assess the association of serum FGF-21 and FGF-23 with the risk of GDM. Furthermore, we evaluated the circulation of these peptides in pregnancy and post-puerperium.

Materials and methods
Fifty-three pregnant subjects with GDM and 43 normal glucose tolerance (NGT) pregnant women participated in this study. Serum FGF-21 and FGF-23 were measured during pregnancy and post-puerperium.

Results
FGF-21 and FGF-23 were low in GDM compared to NGT during pregnancy. There were no significant differences in the level of these peptides post-puerperium. Using logistic regression, FGF-23 [odds ratio (OR) 0.70 (95% confidence interval [CI]: 0.50–0.96)] was inversely associated with GDM, so a 1-μg/mL decrease in FGF-23 levels was associated with a 1.4-fold increased risk of developing GDM and this remained statistically significant after adjustment for confounders [adjusted OR (aOR) 0.70 (95% CI: 0.50–0.98)]. There was no association of FGF-21 with the development of GDM risk.

Conclusions
Lower FGF-23 concentrations could be involved in the pathophysiology of GDM. FGF-21, even though associated with metabolic risk factors in pregnancy, may not be a fundamental factor in GDM.
Preparation and electromagnetic properties characterization of reduced graphene oxide/strontium hexaferrite nanocomposites
Authors: Du Shumin , Chen Huaiyin , Hong Ruoyu 
Published: March 2020

Abstract
With the rapid development of electronics and information technology, electronics and electrical equipment have been widely used in our daily lives. The living environment is full of electromagnetic waves of various frequencies and energy. Electromagnetic wave radiation has evolved into a new type of environmental pollution that has been listed by the WHO (World Health Organization) as the fourth largest source of environmental pollution after water, atmosphere, and noise. Studies have shown that when electromagnetic wave radiation is too much, it can cause neurological disorders. And electromagnetic interference will cause the abnormal operation of medical equipment, precision instruments and other equipment, and therefore cause incalculable consequences. Therefore, electromagnetic protection has become a hot issue of concern to the social and scientific circles.
Review on the research progress of cement-based and geopolymer materials modified by graphene and graphene oxide
Authors: Liu Changjiang , Huang Xiaochuan , Wu Yu-You , Deng Xiaowei , Liu Jian , Zheng Zhoulian , Hui David 
Published: March 2020

Abstract
In recent years, with the higher requirements for the performance of cement-based materials and the call for energy conservation and environmental protection, a wave of research on new materials has set off, and various high-performance concrete and more environmentally friendly geopolymers have appeared in the public. With a view to solving the defects of energy consumption, environmental protection and low toughness of traditional cement-based materials. At the same time, nanomaterials have become a focus of current research. Therefore, the research on the properties of cement-based materials and geopolymers modified by graphene and its derivatives has aroused extensive interest of researchers. Graphene-based nanomaterials are one of them. Because of their large specific surface area, excellent physical properties have been favored by many researchers. This paper reviews the research progress of graphene-based nanomaterials in improving the properties of cement-based materials and geopolymer materials, and points out the main challenges and development prospects of such materials in the construction field in the future.
Using Czechoslovakia and Yugoslavia to predict the outcome of the dissolution of states: factors that lead to internal conflict and civil war
Authors: Kennedy Thomas 
Published: March 2020

AbstractDuring the process of the dissolution of countries, there exist multiple critical junctures that lead to the partition of the territory, where the different groups cannot find a consensus on who rules and how to organize the government. The outcome of these crossroad decisions and political dynamics, who are often set-up centuries ago, either lead to conflict or relative peace between the nations and peoples who express opprobrium towards each other. The most recent cases of the divorce of Yugoslavia and Czechoslovakia have many similitudes and are therefore appropriate to attempt to theoretically analyze the essential difference between these two types of partitions. The Yugoslav situation led to War between the nations of Croatia, Bosnia, Slovenia and Serbia, with an estimated 140,000 citizens of the former Yugoslav Republics killed, while the Czechoslovak case led to an innocuous settlement of differences and the creation of the Czech Republic and Slovakia, who joined the European Union ten years later and saw zero casualties.It is worthwhile to study the relationship between the dissolution of states and conflict using the Czechoslovak and Yugoslav cases for three main reasons. First, the similitude of the two instances enables one to identify variables that bring the outcome of having either peaceful relations or conflict between divorcing nations. Second, it is possible to compare the opposing disposition of variables with other countries that faced dissolution at one moment in history. Third, the sources and research for the two events are extensive, but very seldom put into conflict, since the causes for dissolution in both instances seem patent and explicit, contrasting significantly in scope and depth. This paper may be an occasion to disprove the notion that unworkable forces were at play here and demonstrate that the situation could have skewed in either direction, even though those structural forces are what lay the groundwork of the situation devolving into conflict.
Octafluorobiphenyl-4,4′-dicarboxylate as a ligand for metal-organic frameworks: progress and perspectives
Authors: Cheplakova Anastasia M. , Samsonenko Denis G. , Fedin Vladimir P. 
Published: March 2020

Abstract
While metal-organic frameworks based on aromatic carboxylates are very numerous and well investigated, the chemistry of their fully fluorinated analogues is at the very beginning. This minireview aims at summarizing all metal complexes with octafluorobiphenyl-4,4′-dicarboxylate (oFBPDC2−) anion and in particular, porous coordination polymers, their syntheses, crystal structures and functional properties highlighting the importance of further investigation of such systems.
Using Tensiomyography to Assess Changes in Knee Muscle Contraction Properties After Concentric and Eccentric Fatiguing Muscle Actions
Authors: Muñoz-López Alejandro , De Hoyo Moisés , Nuñez Francisco J. , Sañudo Borja 
Published: March 2020

Abstract
Muñoz-López, A, De Hoyo, M, Nuñez, FJ, and Sañudo, B. Using tensiomyography to assess changes in knee muscle contraction properties after concentric and eccentric fatiguing muscle actions. J Strength Cond Res 36(4): 935–940, 2022—The purposes of this study were to analyze the effects of different types of muscle contraction (concentric and eccentric) on the passive muscular contraction properties of knee muscles and how muscle contraction can affect the muscles in different knee functions. In total, 23 active healthy men (age: 24.65 ± 1.95 years, height: 1.78 ± 0.05 m, mass: 75.33 ± 8.37 kg) participated in this study. Muscle soreness, muscle contractile properties assessed with tensiomyography (TMG) (vastus lateralis [VL] and biceps femoris [BF]), and isometric peak torque were tested before and immediately after 32 maximal repetitions of an isokinetic leg extension and flexion exercise at 180° per second. Muscle contractions were randomized to each subject's leg. From the TMG variables, only contraction velocity showed significant interactions in time × muscle × contraction (p = 0.046; partial

= 0.19). A greater reduction was observed in the BF (−29.03%) than in the VL (−21.25%). There was a significant decrease in contraction velocity after concentric p < 0.001, d = 1.18) and eccentric (p = 0.007, d = 0.51) exercise for the BF, while for VL, a decrease was only observed after concentric exercise (p = 0.007, d = 0.66). The leg extension exercise showed reductions in the isokinetic peak torque (p < 0.001; partial

= 0.83). Isometric peak torque (p < 0.001; partial

= 0.80) and muscle soreness (p < 0.001; partial

= 0.70) decreased after exercise. In conclusion, muscle mechanical properties were differently affected in relation to the muscle contraction and knee muscles involved, after a fatiguing leg extension isokinetic exercise. Isometric peak torque and muscle soreness were also reduced immediately after exercise. These results are particularly important to understand how TMG parameters are modified depending on the type of contraction.
A rare cause of severe Cushing’s syndrome
Authors: Zaman Shamaila , Patel Bijal , Glynne Paul , Vanderpump Mark , Alsafi Ali , Khan Sairah , Flora Rashpal , Palazzo Fausto , Wernig Florian 
Published: March 2020

Summary
Ectopic adrenocorticotropic hormone (ACTH) production is an uncommon cause of Cushing’s syndrome and, rarely, the source can be a phaeochromocytoma. A 55-year-old man presented following an episode of presumed gastroenteritis with vomiting and general malaise. Further episodes of diarrhoea, joint pains and palpitations followed. On examination, he was hypertensive with no clinical features to suggest hypercortisolaemia. He was subsequently found to have raised plasma normetanephrines of 3.98 nmol/L (NR <0.71) and metanephrines of 0.69 nmol/L (NR <0.36). An adrenal CT showed a 3.8 cm right adrenal nodule, which was not MIBG-avid but was clinically and biochemically consistent with a phaeochromocytoma. He was started on alpha blockade and referred for right adrenalectomy. Four weeks later, on the day of admission for adrenalectomy, profound hypokalaemia was noted (serum potassium 2.0 mmol/L) with non-specific ST-segment ECG changes. He was also diagnosed with new-onset diabetes mellitus (capillary blood glucose of 28 mmol/L). He reported to have gained weight and his skin had become darker over the course of the last 4 weeks. Given these findings, he underwent overnight dexamethasone suppression testing, which showed a non-suppressed serum cortisol of 1099 nmol/L. Baseline serum ACTH was 273 ng/L. A preliminary diagnosis of ectopic ACTH secretion from the known right-sided phaeochromocytoma was made and he was started on metyrapone and insulin. Surgery was postponed for 4 weeks. Following uncomplicated laparoscopic adrenalectomy, the patient recovered with full resolution of symptoms.

Learning points:

Phaeochromocytomas are a rare source of ectopic ACTH secretion. A high clinical index of suspicion is therefore required to make the diagnosis.

Ectopic ACTH secretion from a phaeochromocytoma can rapidly progress to severe Cushing’s syndrome, thus complicating tumour removal.

Removal of the primary tumour often leads to full recovery.

The limited literature suggests that the presence of ectopic Cushing’s syndrome does not appear to have any long-term prognostic implications.