bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safe Ground Transport of Pediatric COVID-19 Patients—A Single-Center First-Surge Experience
Authors: McPherson Mona L. , Krennerich Emily C. , Arrington Amy S. , Sitler S. Garry , Graf Jeanine M. 
Published: December 2020

Objectives
The COVID-19 pandemic has brought new challenges to pediatric transport programs. The aims of this study were to describe the transport of pediatric patients with confirmed COVID-19 and to review the operational challenges that our transport system encountered.

Methods
A retrospective descriptive study was performed to review all COVID-19 pediatric transport performed over a 6-month period during the initial pandemic surge in 2020. Pediatric patients with a known positive SARS-CoV-2 polymerase chain reaction test at the time of transport were included. Patients' hospital records, including their transport record, were reviewed for demographics, diagnoses, transport interventions and complications, and admission disposition. Descriptive statistics were used to describe the patient cohort.

Results
Of the 883 transports performed between April and October 2020, 146 (16%) tested positive for COVID-19 during the initial surge in our geographical area. Patient acuity was diverse with 40% of children having a chronic complex medical condition. More than 25% of children required aerosol-generating procedures during transport. The most common medical diagnosis was respiratory compromise, and the most common surgical diagnosis was appendicitis. No adverse events occurred during transports, and no transport team members contracted COVID-19 because of workplace exposure. Transport program operational challenges ranged from rapidly changing system logistics/policies to educational and utilization of proper personal protective equipment.

Conclusions
Children with COVID-19 can be transported safely with adaption of transport program procedures. Change management and team stress should be anticipated and can be addressed with repeated education and messaging.
Posttraumatic Stress Disorder and Chronic Pain Conditions in Men: A Twin Study
Authors: Gasperi Marianna , Panizzon Matthew , Goldberg Jack , Buchwald Dedra , Afari Niloofar 
Published: December 2020

ABSTRACT

Objective
Posttraumatic stress disorder (PTSD) is highly comorbid with chronic pain conditions that often co-occur such as migraine headaches, temporomandibular disorder, irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, chronic prostatitis/chronic pelvic pain syndrome, and tension headaches. Using a genetically informative sample, the current study evaluated the genetic and environmental factors contributing to the co-occurrence of PTSD and chronic pain conditions.

Methods
Data from 4680 male twins in the Vietnam Era Twin Registry were examined. Biometric modeling was used to estimate genetic and environmental variance components and genetic and environmental correlations between PTSD and multiple chronic pain conditions.

Results
Heritabilities were estimated at 43% (95% confidence interval [CI] = 15%–63%) for PTSD and 34% (95% CI = 27%–41%) for the combined history of any one or more pain condition. Specific pain condition heritabilities ranged from 15% (95% CI = 0%–48%) for tension headaches to 41% (95% CI = 27%–54%) for migraine headaches. Environmental influences accounted for the remaining variance in pain conditions. The genetic correlation between PTSD and combined history of any one or more pain condition was r
g
= 0.61 (95% CI = 0.46–0.89) and ranged for individual pain conditions from r
g
= 0.44 (95% CI = 0.24–0.77) for migraine headache to r
g
= 0.75 (95% CI = 0.52–1.00) for tension headaches.

Conclusions
PTSD and chronic pain conditions are highly comorbid, and this relationship can be explained by both genetic and environmental overlap. The precise mechanisms underlying these relationships are likely diverse and multifactorial.
Brain Contrast-Enhanced Ultrasound Evaluation of a Pediatric Swine Model
Authors: Hwang Misun , Khaw Kristina , Sridharan Anush , Poznick Laura , Hallowell Thomas , Delso Nile , Roberts Anna L. , Kilbaugh Todd J. 
Published: December 2020

Abstract
Brain injury remains a leading cause of morbidity and mortality in children. We evaluated the feasibility of using a pediatric swine model to develop contrast-enhanced ultrasound (CEUS)–based measures of brain perfusion for clinical application in various types of brain injury monitoring. Six-week-old, 10-kg swine (N = 10) were anesthetized, and an acoustic window was created in the right frontal cranium to provide visualization of an oblique coronal plane and bilateral thalami. Ultrasound contrast agent was administered via a femoral venous catheter as a weight-based (0.03 mL/kg) bolus. After localization of the imaging plane, CEUS cine clips were acquired for 90 seconds. Bolus injection of contrast agent provided global visualization of cerebral perfusion and highlighted microvasculature in the brain. Preliminary evaluation of bolus kinetics in piglets showed a central gray nuclei–to–cortex ratio similar to human infants with a steep wash-in that crossed and remained above the 1.0 threshold for most of the enhancement period. We demonstrated the similarity in brain perfusion between piglets and human infants, specifically central gray nuclei–to–cortex ratio, showing preliminary feasibility of its use as a pediatric model of brain perfusion. Contrast-enhanced ultrasound can be performed at the bedside as a minimally invasive procedure, and quantitative CEUS may provide critical information regarding changes in brain perfusion as a result of injury or as a response to therapy.
Can general and particularistic types of trust mix? Advancing the trust (dis-) continuity debate in a Chinese context
Authors: Horak Sven , Klein Andreas , Li Xiaomei 
Published: December 2020

PurposeWe challenge the discontinuity (also called incompatibility) hypothesis of generalized and particularistic trust, suggesting that the two types of trust are incompatible. This view is problematic because if so, it remains unclear, for instance, how communities scoring high in particularistic trust can ever develop further when transferring trust to spheres outside the community is not an option. In this research, we explore the potential permeability of different types of trust in an emerging market context using the case of China.Design/methodology/approachUsing a purposeful sampling technique, we gathered data among Chinese professionals (n = 290) in the Jingjinji Metropolitan Region in Tianjin. We analyzed the data by performing structural equation modeling.FindingsAs we identify interdependencies between generalized and particularistic types of trust, our results speak in favor of the continuity hypothesis. We find that the more people trust other people from an outside group (out-group trust), the less they trust quasi-familiar others (in-group trust). Further, in-group trust increases once the environment urges people to engage in informal network (guanxi)-based transactions.Originality/valueAdvancing the common view of China being a typical low-trust society, in which distrust in strangers (outsiders) prevails, we find a recent trend of an increase in general trust, which might lead to increases of out-group and in-group trust alike. Contrary to the wide spread idea thatguanxiis declining in the present day, we findguanxito be persistent.
An emerging genre of contemporary fact-checking
Authors: Juneström Amalia 
Published: December 2020

PurposeBy exploring the social features of contemporary fact-checking this study aims to increase our understanding of fact-checking as a genre and shed light on some of the aspects that underpin the communication that fact-checkers engage in.Design/methodology/approachBy analyzing one snapshot of early COVID-19 coverage by three well-known fact-checkers and another one six months later, this study explores fact-checking as a genre. The material was examined for recurrent characteristics and the findings were categorized into corresponding themes that emerged through an open coding process.FindingsThree aspects were found to underpin a contemporary fact-checking genre. Firstly, the fact-checkers strive to facilitate accessibility. Secondly, the notion of building trust underlies the way fact-checkers promote themselves. Thirdly, fact-checking is underpinned by a pedagogical aspect. While the values and beliefs that are known to characterize traditional news media discourses are predominant in the construction of a fact-checking genre, fact-checkers also draw on conceptions typically found within academia to enact professional practices.Originality/valueContemporary fact-checking is still a fairly unexplored topic of research. This is particularly the case outside the field of journalism and media studies. This study complements earlier research from the perspective of information studies by exploring how fact-checking practices impact the communication and production of news in society.
Acting hot or not? Testing the citing to show-off hypothesis
Authors: Nicolaisen Jeppe , Frandsen Tove Faber 
Published: December 2020

PurposeCitation analysis as a method for studying scientific communication is frequently criticized for being based on biased citation practices. Questionable motives for the reference selection have been suggested including the claim that authors tend to cite hot papers in order to show-off. In this study, the authors investigate the claim that authors tend to cite the recent literature in order to show-off.Design/methodology/approachFollowing Moed and Garfield (2004), the authors investigate the claim by analyzing the proportion of recent references as a function of the length of the reference lists of citing papers. The authors analyze reference lists of citing papers in the fields of biomedical engineering, economics, medicine, psychology and library and information science between 2010 and 2019. From each of these fields, a number of journals are included in the analysis to represent the field. In total, 42 journals are included in the analyses comprising a selection of almost 65,000 journal articles. The proportion of recent references is calculated using two citation windows. The proportion of recent references as a function of the length of the reference lists is calculated through simple linear regressions to predict the share of recent references based on the number of references.FindingsThe results of the linear regressions indicate that in most cases, there are a statistically significant relationship between the share of recent references and the number of references. This study’s results show that when authors display selective referencing behavior, references to the recent literature tend to be only marginally increased, and some results even display the opposite tendency (marginally overciting the older literature).Originality/valueThis study of the claim that authors tend to cite the recent literature in order to show-off does not confirm the hypothesis.
Senior housing in Scotland: a development and investment opportunity?
Authors: Fyfe Andrew , Hutchison Norman 
Published: December 2020

PurposeThis article aims to understand the housing needs of older people and to ascertain the level of demand and supply of age-related housing in Scotland. It also explores interest in different types of retirement accommodation and tenure options.Design/methodology/approachA review of existing literature is undertaken on senior housing preferences and residential satisfaction. Primary data is collected from an online survey of people over 55 in Scotland to ascertain demand side requirements with secondary data on current supply obtained from the Elderly Accommodation Counsel and data on future pipeline collated from market reports.FindingsThe results from the survey confirm earlier research that seniors when looking for accommodation in their retirement years particularly focus on the local area, access to shops, social relations with neighbours and the design of the home interior. Current analysis of the level of supply at a county level reveals that there is significant undersupply with some particularly striking regional differences. Along with a desire for owner occupation there is interest, particularly among the 75 plus age group, to lease their accommodation, perhaps a consequence of volatile property markets, insufficient pension provision or a desire to pass wealth to their family prior to death. This shortfall in supply highlights development opportunities and raises the possibility of introducing a build-to-rent senior housing offering, which may be of interest to institutional investors.Practical implicationsThe Scottish Government is currently reviewing its strategy for Scotland's older people. The results are of practical benefit as they expose the gaps in supply of age-related stock at county level. This may require the government to introduce policy measures to encourage a mix of housing types suited for the ageing demographics of the population. This research highlights opportunities for developers and investors to fill that gap and explains why advancements in technology should be incorporated in the design process.Originality/valueThis paper brings together supply side data of senior housing in Scotland and provides insights into the housing preferences of seniors. It will be of direct value and interest to developers and institutional investors.
Information management during a crisis – providing an open and reliable information infrastructure for a sustainable world
Authors: Saarti Jarmo 
Published: December 2020

PurposeThe purpose of this paper is to analyze the impact of the corona situation on the academic library services, policies and activities.Design/methodology/approachThe methodology of the paper is opinion piece based on experiences.FindingsThere is a need for global policymaking for both the open academic resources dissemination and crisis management.Originality/valueThe originality of the paper is based on recent experiences.
Toxin or medication? Immunotherapeutic effects of nicotine on a specialist caterpillar
Authors: Garvey Michael , Bredlau Justin , Kester Karen , Creighton Curtis , Kaplan Ian 
Published: December 2020

Abstract

A core tenant in the field of ecological immunology is that immune responses trade off with other physiological functions due to resource allocation costs. Caterpillars, for example, tend to exhibit reduced immune responses when reared on more toxic food plants due to a cost from detoxifying or sequestering secondary metabolites, also known as the ‘vulnerable host hypothesis’. However, support for this hypothesis is mixed, and studies have not yet mechanistically isolated the relative contributions of total plant defences, specific metabolites or macro‐nutritional quality.

We used the tobacco hornworm Manduca sexta, a specialist herbivore on plants in the nightshade family (Solanaceae), to investigate trade‐offs in immune response. This system is ideal given the availability of solanaceous plant lines varying in general (i.e. jasmonate‐induced) and specific (i.e. nicotine) resistance traits. We also applied a geometric diet stoichiometry approach to examine how phytochemical toxicity and nutritional quality interactively impact insect immunity and performance. We predicted that as plant toxicity increased, immune activity and herbivore performance would decrease.

Increasing food plant toxicity reduced insect growth and development, as predicted, but contrary to our hypothesis, plant toxicity did not trade off with immune parameters. Surprisingly, specific plant chemicals, in this case nicotine, appeared immunotherapeutic, stimulating the phenoloxidase (PO) immune response of M. sexta. Available nutrients in artificial diets, mainly protein, also strongly impacted insect growth, but did not affect PO activity, while diets supplemented with nicotine enhanced the PO and melanization response.

This work highlights how specific secondary metabolites, and not overall plant toxicity, impact the immune response. Importantly, our data also suggest an alternative mechanism (i.e. immune enhancement) for reduced parasitoid performance when reared from hosts on toxic plants via tritrophic interactions.

A free Plain Language Summary can be found within the Supporting Information of this article.
Research Note: Recovering sparse models in 3D potential‐field inversion without bound dependence or staircasing problems using a mixed Lp norm regularization
Authors: Sun Jiajia , Wei Xiaolong 
Published: December 2020

ABSTRACTSparse inversions have proven to be useful for interpreting potential‐field data because the recovered models are characterized by sharp boundaries, compact features and elevated values, compared with conventional smoothness‐based inversion results. However, several open problems remain to be addressed, including the bound dependence and staircasing problems. The former results in recovered anomalous values being close to the upper bound, while the latter leads to recovered anomalous bodies with either horizontal or vertical boundaries. We have developed a mixed Lp norm regularization strategy to address these two problems. Inversion results based on two synthetic examples confirm the validity of our approach.
Cell and extracellular matrix interaction models in benign mesothelial and malignant pleural mesothelioma cells in 2D and 3D in‐vitro
Authors: Jagirdar Rajesh M. , Papazoglou Eleftherios D. , Pitaraki Eleanna , Kouliou Olympia A. , Rouka Erasmia , Giannakou Lydia , Giannopoulos Stefanos , Sinis Sotirios I. , Hatzoglou Chrissi , Gourgoulianis Konstantinos I. , Zarogiannis Sotirios G. 
Published: December 2020

AbstractMalignant pleural mesothelioma (MPM) is an aggressive tumour that grows in the pleural cavity. MPM spheroids released in the pleural fluid can form new tumour foci. Cell–cell, cell–extracellular matrix (ECM) interactions in 2D and 3D impact malignant cell behaviour during cell adhesion, migration, proliferation and epithelial–mesenchymal transition (EMT). In this study, epithelioid, biphasic and sarcomatoid MPM cell types as well as benign mesothelial cells were tested with regards to the above phenotypes. Fibronectin (FN) and homologous cell‐derived extracellular matrix (hcd‐ECM) treated substratum differentially affected the above phenotypes. 3D MPM spheroid invasion was higher in FN‐collagen matrices in the epithelioid and biphasic cells, while 3D cell cultures of epithelioid and sarcomatoid MPM cells in FN‐collagen showed a higher contractility compared to hcd‐ECM‐collagen. Cell aggregates demonstrated invasive behaviour in hcd‐ECM matrices alone. Our results suggest that ECM and the dimensionality affect malignant cell behaviour during cell culture studies.
Analysis of bacterial communities in a municipal duck pond during a phytoplankton bloom and isolation of Anatilimnocola aggregata gen. nov., sp. nov., Lacipirellula limnantheis sp. nov. and Urbifossiella limnaea gen. nov., sp. nov. belonging to the phylum Planctomycetes
Authors: Kallscheuer Nicolai , Rast Patrick , Jogler Mareike , Wiegand Sandra , Kohn Timo , Boedeker Christian , Jeske Olga , Heuer Anja , Quast Christian , Glöckner Frank Oliver , Rohde Manfred , Jogler Christian 
Published: December 2020

SummaryWaterbodies such as lakes and ponds are fragile environments affected by human influences. Suitable conditions can result in massive growth of phototrophs, commonly referred to as phytoplankton blooms. Such events benefit heterotrophic bacteria able to use compounds secreted by phototrophs or their biomass as major nutrient source. One example of such bacteria are Planctomycetes, which are abundant on the surfaces of marine macroscopic phototrophs; however, less data are available on their ecological roles in limnic environments. In this study, we followed a cultivation‐independent deep sequencing approach to study the bacterial community composition during a cyanobacterial bloom event in a municipal duck pond. In addition to cyanobacteria, which caused the bloom event, members of the phylum Planctomycetes were significantly enriched in the cyanobacteria‐attached fraction compared to the free‐living fraction. Separate datasets based on isolated DNA and RNA point towards considerable differences in the abundance and activity of planctomycetal families, indicating different activity peaks of these families during the cyanobacterial bloom. Motivated by the finding that the sampling location harbours untapped bacterial diversity, we included a complementary cultivation‐dependent approach and isolated and characterized three novel limnic strains belonging to the phylum Planctomycetes.
A delicate balance between control and flexibility: Experiences of care and support among pre‐teenage children with type 1 diabetes and their families
Authors: Pals Regitze Anne Saurbrey , Coyne Imelda , Skinner Timothy , Grabowski Dan 
Published: December 2020

AbstractFor children with type 1 diabetes, the period of adolescence is associated with higher blood glucose levels and increased psychological distress compared to other age groups. Focusing on pre‐teens (9‐12 years) with type 1 diabetes and their families has been suggested as key to understanding and reducing these challenges. The aim of this study was to explore: 1, how diabetes affects family life, 2, experiences of and needs for support and 3, how care responsibilities are negotiated among pre‐teens with type 1 diabetes and their families. Data were obtained from four interactive workshops with pre‐teens (n = 17), their parents (n = 26) and their siblings (n = 14). Dialogue tools, for example quotes and picture cards, were used to facilitate discussion and reflection concerning family life with type 1 diabetes. Data analysis resulted in three themes: 1, diabetes takes up ‘a lot of space’, 2, giving and receiving support and 3, balancing control and flexibility. While diabetes took up significant space in the families, family members protected each other from their respective frustrations. The findings point to the significance of considering all key family members and their interactions in diabetes interventions. This includes balancing control and flexibility, negotiating responsibilities and building trust.
Heterotopia of the road: driving and drifting in Siberia
Authors: Argounova‐Low Tatiana 
Published: December 2020

AbstractThe article demonstrates how development of the car cultures in the city of Yakutsk, northeastern Russia, is facilitated by the proximity of Japan, where street racing and drift driving became popular through such outlets as the manga series, animation films, YouTube, and a blockbuster film, The Fast and the Furious: Tokyo Drift. These influences, which arrived in Siberia from across the Sea of Japan and Hollywood, highlight the shifting geographies and multiple cultural entanglements of the technological advancements in the global space. Through these cultural engagements, young people in the city establish a different perception of the road, endowing it with heterotopic qualities. The article explores the heterotopia of the road in anthropology.