bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stereotactic irradiation of non-small cell lung cancer brain metastases: evaluation of local and cerebral control in a large series
Authors: Fessart Etienne , Mouttet Audouard Raphaëlle , Le Tinier Florence , Coche-Dequeant Bernard , Lacornerie Thomas , Tresch Emmanuelle , Scherpereel Arnaud , Lartigau Eric , Mirabel Xavier , Pasquier David 
Published: July 2020

AbstractStereotactic radiotherapy (SRT) of brain metastases (BM) results are often reported in the heterogeneous primitive population. Here, we report our experience in consecutively treated patients who underwent SRT alone for BM from non-small cell lung cancer (NSCLC). This retrospective analysis included consecutive patients with no history of cerebral treatment who underwent Cyberknife™ SRT for BM from NSCLC in our institution from 2007 to 2016. One hundred patients were included in the study, with a median follow-up of 33 months (20–64). Mean age was 63 years (SD ± 10); 88% had Karnofsky Performance Status (KPS) > 70; 67% had unique BM; 18 patients received single-fraction SRT (20–25 Gy), and 82 received hypo-fractionated SRT (HSRT) (24–36 Gy in 3–5 fractions). We reported a complication rate of 17% (2% of G3-4). Median survival was 10.1 months [95% confidence interval (CI) 7.8–13.9]. At 1 year, local and cerebral control rates were respectively 78.7% (95% CI 70–86.5%) and 43% (95% CI 33.5–53%). Thirty patients underwent salvage treatment (whole brain radiation therapy, n = 13; SRT, n = 14; surgery, n = 3). Cyberknife™-based SRT is an effective treatment associated with high local control rate with low morbidity for patients with NSCLC’s BM. Close follow-up is necessary to perform salvage treatment.
Comments on ‘Association of FcϵRIβ polymorphisms with risk of asthma and allergic rhinitis: evidence based on 29 case–control studies’
Authors: Yang Haijun , Zheng Lan , Zhang Yanmei , Yang Min , Wei Sha 
Published: July 2020

Abstract
Guo et al. (Bioscience Reports (2018) 38, BSR20180177) published a meta-analysis concerning the association between five single nucleotide polymorphisms (SNPs) in the high-affinity IgE receptor β chain (FcεRIβ) gene, namely E237G, -109 C/T, RsaI_in2, RsaI_ex7, and I181L, and risk of asthma and allergic rhinitis based on available 29 case–control studies. Summary odds ratios (ORs) and 95% confidence intervals (CIs) were used to assess the strength of association of SNPs in FcεRIβ gene with allergic diseases risk. They found that FcεRIβ E237G (237G vs. 237E: OR = 1.28, 95% CI = 1.06–1.53) and −109 C/T (TT vs. CT+CC: OR = 1.58, 95% CI = 1.26–1.98) were risk factors for allergic diseases. Guo et al.’s findings are interesting, but we found that several issues should be clarified after carefully reading the paper. Here, we intended to comment on these data clarifications.
Toward an Individualized Neural Assessment of Receptive Language in Children
Authors: Petit Selene , Badcock Nicholas A. , Grootswagers Tijl , Rich Anina N. , Brock Jon , Nickels Lyndsey , Moerel Denise , Dermody Nadene , Yau Shu , Schmidt Elaine , Woolgar Alexandra 
Published: July 2020

Purpose
We aimed to develop a noninvasive neural test of language comprehension to use with nonspeaking children for whom standard behavioral testing is unreliable (e.g., minimally verbal autism). Our aims were threefold. First, we sought to establish the sensitivity of two auditory paradigms to elicit neural responses in individual neurotypical children. Second, we aimed to validate the use of a portable and accessible electroencephalography (EEG) system, by comparing its recordings to those of a research-grade system. Third, in light of substantial interindividual variability in individuals' neural responses, we assessed whether multivariate decoding methods could improve sensitivity.

Method
We tested the sensitivity of two child-friendly covert N400 paradigms. Thirty-one typically developing children listened to identical spoken words that were either strongly predicted by the preceding context or violated lexical–semantic expectations. Context was given by a cue word (Experiment 1) or sentence frame (Experiment 2), and participants either made an overall judgment on word relatedness or counted lexical–semantic violations. We measured EEG concurrently from a research-grade system, Neuroscan's SynAmps2, and an adapted gaming system, Emotiv's EPOC+.

Results
We found substantial interindividual variability in the timing and topology of N400-like effects. For both paradigms and EEG systems, traditional N400 effects at the expected sensors and time points were statistically significant in around 50% of individuals. Using multivariate analyses, detection rate increased to 88% of individuals for the research-grade system in the sentences paradigm, illustrating the robustness of this method in the face of interindividual variations in topography.

Conclusions
There was large interindividual variability in neural responses, suggesting interindividual variation in either the cognitive response to lexical–semantic violations and/or the neural substrate of that response. Around half of our neurotypical participants showed the expected N400 effect at the expected location and time points. A low-cost, accessible EEG system provided comparable data for univariate analysis but was not well suited to multivariate decoding. However, multivariate analyses with a research-grade EEG system increased our detection rate to 88% of individuals. This approach provides a strong foundation to establish a neural index of language comprehension in children with limited communication.

Supplemental Material

https://doi.org/10.23641/asha.12606311
It's About Time: Minimizing Hardware and Software Latencies in Speech Research With Real-Time Auditory Feedback
Authors: Kim Kwang S. , Wang Hantao , Max Ludo 
Published: July 2020

Purpose
Various aspects of speech production related to auditory–motor integration and learning have been examined through auditory feedback perturbation paradigms in which participants' acoustic speech output is experimentally altered and played back via earphones/headphones “in real time.” Scientific rigor requires high precision in determining and reporting the involved hardware and software latencies. Many reports in the literature, however, are not consistent with the minimum achievable latency for a given experimental setup. Here, we focus specifically on this methodological issue associated with implementing real-time auditory feedback perturbations, and we offer concrete suggestions for increased reproducibility in this particular line of work.

Method
Hardware and software latencies as well as total feedback loop latency were measured for formant perturbation studies with the Audapter software. Measurements were conducted for various audio interfaces, desktop and laptop computers, and audio drivers. An approach for lowering Audapter's software latency through nondefault parameter specification was also tested.

Results
Oft-overlooked hardware-specific latencies were not negligible for some of the tested audio interfaces (adding up to 15 ms). Total feedback loop latencies (including both hardware and software latency) were also generally larger than claimed in the literature. Nondefault parameter values can improve Audapter's own processing latency without negative impact on formant tracking.

Conclusions
Audio interface selection and software parameter optimization substantially affect total feedback loop latency. Thus, the actual total latency (hardware plus software) needs to be correctly measured and described in all published reports. Future speech research with “real-time” auditory feedback perturbations should increase scientific rigor by minimizing this latency.
Determination of the working area of a hydraulic excavator
Authors: Shestakov Victor , Bezkorovainyy Pavel , Franz Tatyana 
Published: July 2020

The relevance of the work is due to the need of the design departments involved in the design of hydraulic excavators in techniques that reduce the mass of excavators while providing the required technological capabilities. Existing methods are aimed at determining the size of working equipment on the condition of providing a given working area. The methods are based on an algorithm for calculating the boundaries of the working area for the input dimensions of the boom, stick and bucket, if the obtained boundaries do not correspond to the specified ones, then the dimen-sions of the equipment are adjusted and the calculations are repeated. The boundaries of the working zone determined by these algorithms do not take into account the power capabilities - the bucket can be at a given point, but the realized forces on the teeth do not ensure separation of the rock. The article discusses the methodology in which possible digging efforts are calculated at all points where the bucket can be located.
Results. For a hydraulic excavator with working equipment “direct shov-el”, a mathematical model for calculating digging forces, an algorithm and a program in algorithmic language have been developed to determine possible forces in the elements of the working equipment.
Peptide Cyclization at High Concentration
Authors: Raj Monika , Wills Rachel D. , Adebomi Victor T. 
Published: July 2020

The emergence of cyclic peptides as pharmaceuticals has led to an eruption of new methodologies for macrocyclization. However, the cyclization of peptides at high concentrations presents a challenge due to the production of side products like dimers and oligomers. This factor is more pronounced with the cyclization of peptides composed of fewer than seven amino acids, thus has created a need for a new synthetic strategy. Herein, we will elucidate a new chemoselective method termed ‘CyClick’ that works in an exclusively intramolecular fashion preventing the formation of commonly occurring side products such as dimers and oligomers, even at relatively high concentration.1	Introduction2	Known Methodologies3	Novel CyClick Chemistry4	Conclusion and Outlook
A corpus study ofkasama‘companion’ in Tagalog
Authors: Klimenko Sergei 
Published: July 2020

AbstractThis paper presents a corpus-based study of a number of different types of previously undescribed constructions formed with the Tagalog nounkasama‘companion’. Apart from independent and attributive uses,kasamafrequently occurs as the predicate of an adjunct clause that can introduce a comitative participant, a semantically depictive secondary predicate, an event-oriented adjunct, or a predicative complement. The study analyses the frequency ofkasamain all of these types of constructions and looks into their specific properties. This includes: the semantic distinction between additive and inclusory constructions withkasama; animacy agreement between arguments ofkasamain additive constructions; variation in case marking of arguments ofkasama; the preponderance of the absence of linkers – commonly known to introduce adverbial clauses in Tagalog – which are used to attach thekasamaclause to the main clause; attested controllers of thekasamaclause; positions available for thekasamaclause in the sentence. Variation in case marking and compatibility with linkers suggests a classification of Tagalog adjunct clauses similar to that of Tagalog adverbials and prepositions. There is also some evidence to believe thatkasamais being grammaticalized as a preposition. Comitative and semantically depictive constructions withkasama, which account for a quarter of the corpus sample, have never been studied before, despite the fact that Tagalog is included in several typological studies on comitative and depictive constructions.
Is inhibition involved in the processing of opaque compound words?
Authors: Park Juana , Sana Faria , Gagné Christina L. , Spalding Thomas L. 
Published: July 2020

AbstractWe examined whether inhibition skills were recruited during the processing of compound words. Using an individual differences perspective, we analyzed whether participants’ scores on the Stroop test predicted performance on lexical decision tasks involving compound words varying in their level of semantic opacity. The results show that inhibition is involved in the comprehension of fully opaque (e.g.,hogwash) and fully transparent (e.g.,blueberry) compound words, but we found no evidence for such an effect in the comprehension of partially opaque compound words (e.g.,strawberry,jailbird).
Negotiating embodied space in anxiety narratives
Authors: Knapton Olivia 
Published: July 2020

Abstract
In recent years, studies from social/cultural geography and social psychology have shown the importance of the subjective experience of space in anxiety disorders. This study investigates how lived space in anxiety is discursively negotiated in interactional narratives, with a focus on the co-construction of time, physical space and epistemic modality, and the ways in which metaphors contribute to the representation of spatial experience. The data are two case studies taken from television programmes in which a figure in the public eye is being interviewed about their experiences of anxiety. The analysis showcases two distinct kinds of lived space in anxiety, one in which the self is continually moving through a space experienced as too expansive, and another in which other people/entities are moving around the self in a space experienced as too small. Both experiences involve spatial responses that serve to bring some relief from anxiety. The analysis also has methodological implications by exemplifying how metaphors feed into spatial gestalts that are collaboratively constructed as narratives unfold in situated interaction.
A mixed-method analysis of image-schematic metaphors in describing anger, anxiety, and depression
Authors: Yu Yating , Tay Dennis 
Published: July 2020

Abstract
The importance of metaphor in psychotherapy and counseling has been shown by a growing number of studies.
Image-schematic metaphors, which derive from experience of sensory processes and space, are potential resources for
conceptualizing major themes like anger, anxiety, and depression in therapeutic discourse. To test the potential correlation
between image-schematic metaphors and the themes of anger, anxiety, and depression, this study employs a mixed-method approach,
integrating corpus linguistics techniques, discourse analysis, and statistical analysis, to examine a specialized corpus of
therapeutic transcripts which contains approximately three million words. The findings show that containment, force,
path, and vertical orientation are the most frequent types of image-schematic metaphors for describing the
therapeutic themes of anger, anxiety, and depression in the corpus, and there is a significant correlation between the two
variables (i.e., “types” and “themes”). This study has implications for how image-schematic metaphors can be used to facilitate
the descriptions of anger, anxiety, and depression in therapeutic conversations.
The ‘transformative’ power of ‘integrated metaphor’ in counselling
Authors: Ferrari Federica 
Published: July 2020

Abstract
Given the centrality of metaphor in the (re)structuring of experience (Burns,
2005; Loue, 2008; Roffman, 2008)
and of bodily experience to the notion of conceptual metaphor in cognitive theory (Lakoff
& Johnson, 2003 [1980]; Lakoff, 1993; Gibbs, 2006), this paper investigates the ‘transformative power’ of metaphor in ‘talking cure’
practices – Counselling and Psychotherapy – to implement its application potential. An experimental integrated “metaphor-based and
-driven” model is presented by adapting textual identification procedures (Steen, 1999;
Ferrari, 2007; Pragglejaz, 2007) to an
integrated psychological approach (Rogers, 2003 [1951]; Perls, 1951) in order to
further develop metaphor transformation guidelines. The ‘M’ psycho-test had been created to evaluate the power of metaphor in
counselling sessions in a diachronic perspective, providing both qualitative and quantitative data. Some preliminary cases (e.g.
‘the frog’, ‘eating’, ‘the hare’, ‘the desolated land’) are presented, with relative Transformational score, as examples of test
application and metaphor potential. Test evidence has allowed for quantitative and qualitative observations. The evidence gathered
shows: (1) Applying a metaphor-based experimental integrated approach can offer alternative for action in the practice; (2)
Measuring the transformational power of metaphor through ‘M’ psycho-test can offer further degree of awareness for both counsellor
and client.
Rewriting burnout as metaphor
Authors: Johnson Carissimo Melissa 
Published: July 2020

Abstract
Today’s healthcare professionals shoulder consequences of budget cuts, staff shortages, longer hours and a
growing, aging patient population. To address support for both patients and staff in this challenging context, the kidney dialysis
unit of a major Italian hospital was chosen for a three-phase pilot study of Metaphoric Affect Processing (MAP). MAP is a
metaphor-based interview technique designed to enhance wellbeing in hospital settings by facilitating the identification,
verbalization and regulation of affect as metaphor. The subject of this article is Phase 1 of the study, which focused on
mitigation of burnout symptoms among peritoneal and hemodialysis nurses. In Phase 1, nurses were offered weekly group sessions of
MAP training. All participants learned to use codified, “poetic” dialogue to explore, share and metaphorically “rewrite”
present-moment feelings. By the end of training, a number of nurses also qualified as MAP facilitators themselves. Nurses’
pre-training burnout levels were measured in subcategories of depressive anxiety, loss of empathy, and reduced sense of personal
achievement. Assessment after MAP training confirmed nurses’ self-reports of having engaged metaphor to address these aspects of
burnout, reducing stress levels, increasing empathy among colleagues and expanding perspective. Phase 1 outcomes suggest that MAP
may be an effective intervention to boost wellbeing for healthcare workers at high risk for burnout, and merits further study.
This article also offers an overview of MAP’s early development with patient populations in cancer treatment and acute care
psychiatric settings.
Cause analysis of transverse breakage of ultra high-strength steel shell after hydraulic blasting test
Authors: Wang H Y , Wang X , Yao Ch Ch , Liang X P , Zh Ren Zh , Chen X Y , Zhou F L , Wi Tong Sh 
Published: July 2020

Abstract
To ensure product quality, the inspection and analysis were carried out on the ultra high-strength steel welded shell with transverse rupture after qualified hydraulic blasting test. Firstly, we carried out spot investigation of hydraulic blasting test, breakage morphological analysis, investigation on production technology, reexamination of wall-thickness and X-ray film of welding joint; in case of different opinions on fast analysis, then, we carried out contrast detection and analysis on stripe of fracture, metallographic analysis on cross section of welding joint, TEM detection and analysis on fracture, and inspection and analysis on welding size and offset. The analysis results showed that, the transverse rupture of test sample after hydraulic blasting test was caused by the failure of part incomplete joint penetration on welding joint, which was due to welding arc deviation. Therefore, with the improvements of welding equipments, tooling and operation methods to prevent radial and weld offset, the welding quality was assured and improved.
The influences of annealing on surface morphology and microstructure of NdFeB thin film
Authors: Guo Z Z , Cao J W , Yan D M , Liu F F , Zhang C , Guo J B , Fu Y D 
Published: July 2020

Abstract
NdFeB thin films are produced by DC magnetron sputtering. The influences of annealing on surface morphology and microstructure of NdFeB thin films are studied in this paper. The result shows that the formation of Nd2Fe14B is prevented by depositing film directly on the substrates. Nd2Fe14B phase exists in crystalline films with Mo as a buffer layer and protective layer. Mo is a good material for being a buffer layer and protective layer. The (110) oriented texture of Mo is formed on (100) mirror polished Si after annealing. The deposited films are amorphous. SEM results show that the grain size is fine and uniform after annealing. Atomic Force Microscope investigation reveals that the film is smoother and denser after annealing. It is found that the films are still amorphous with annealing temperature below 400 °C, and the films begin to crystallize after annealing at 500 °C; the films annealed at 600 °C are fully crystallized.
Investigations on the influence of one and two-sided jet deflector on acoustic environment of multi-nozzle launch vehicle at lift-off
Authors: Xing Ch L , Le G G , Zhao Ch F , Zheng H 
Published: July 2020

Abstract
To study the acoustic environment of multi-jet impinging the jet deflector when the launch vehicle takes off, a compressible flow model of gas-air is established. The turbulence equation of scale-adaptive simulation (SAS) and the acoustic analogy method (FW-H) are solved numerically by using the second-order Roe scheme. The jet noise of a single rocket engine is numerically simulated. The error between numerical results and experimental data is within 3dB, and the reliability of the numerical method is verified. On this basis, the flow field and acoustic environment of the multi-nozzle launch vehicle are studied, and the effects of the jet deflector configurations on the acoustic environment of the vehicle are analyzed. The results show that, compared with the one-sided jet deflector, the two-sided jet deflector can reduce the overall sound pressure level around the vehicle by up to 6.6%. For the one-sided jet deflector, the overall sound pressure level of the receivers at the outlet of the jet deflector is larger than that of the other side. The analysis method and research results in this paper provide reference for predicting the acoustic environment of the launch vehicle and improving the acoustic environment.
The design of low-velocity penetrating equipment for high-energy explosives
Authors: Mei FENG 
Published: July 2020

Abstract
Accident scenarios involving explosive workers handling cased charges can result in low-velocity impact incidents. A series of low-velocity penetrating safety researches and experiments should be performed to high-energy explosives, and to determine whether such a penetrating impact can cause ignition and violent reaction, and to demonstrate heat generation mechanisms of low-velocity penetrations. This design of low-velocity penetrating equipment seeks to imitate the accident scenarios, perform safety researches and experiments, and demonstrate heat generation mechanisms of low-velocity penetrating for high-energy explosive. The structure design, controller design, control software design and test effects were elaborated in this paper.