bluuebunny/crossref_metadata_2025_split huggingface dataset:
Why do we need renewables?
Authors: Jelley Nick 
Published: March 2020

Abstract
‘Why do we need renewables?’ describes the dangers of fossil fuels and explains the importance of renewable energy as an alternative. It shows that the use of fossil fuels causes global warming and climate change, leading to widespread concern, and also to a growing realization of the harm caused by the air pollution from coal burning and from internal combustion engines in cars and lorries. These threats are causing a switch away from fossil fuels to renewables that is gaining impetus from the growing awareness of the increased intensity and frequency of extreme weather seen in recent years. This transition is also being aided by the falling price of clean energy from renewables, in particular, solar and wind farms, which will become the dominant sources. The area of land or sea required for these farms is readily available, as are the back-ups required to handle their variability. Alternative supplies of low-carbon energy are examined. In the Paris Agreement in 2015, it was recognized that carbon dioxide emissions must reach net-zero by 2050 to avoid dangerous climate change.
Other low-carbon technologies
Authors: Jelley Nick 
Published: March 2020

Abstract
‘Other low-carbon technologies’ examines other low-carbon technologies, and sees how they fare against those already discussed in previous chapters. These are the renewables: tidal, wave, and geothermal power; and the low-carbon technologies of nuclear power and carbon capture. The contribution from tidal and wave power is small, with only a few tidal stream and underwater wave devices under development, and that the power from geothermal sources is potentially large, but difficult to extract. The deployment of nuclear power has been affected by concerns over its safety, the disposal of its waste, and its cost. By 2050, the total generation from all renewables and nuclear power could be close to 90 per cent of current global demand. While capture at fossil-fuel power plants looks uncompetitive, air capture through reforestation and through using chemical absorbers might remove 10 per cent of the emissions of carbon dioxide and help the world to be on target to achieve net-zero emissions.
Renewable electricity and energy storage
Authors: Jelley Nick 
Published: March 2020

Abstract
‘Renewable electricity and energy storage’ addresses the transmission of electricity using high voltage alternating or direct current (HVAC or HVDC), the effect of the variability of renewable energy supplies, and the importance of energy storage. Solar and wind farms are now providing an increasing proportion of electricity on many electricity grids. This is changing the requirements on power plants, requiring fast-reacting generators, interconnectors to other grids, demand response, smart grids, and energy storage. There is a cost in accommodating the variability in supply of electricity from wind and solar farms, and surplus supply can lower revenues and give rise to a ‘missing money problem’. Lithium-ion batteries are increasingly important in providing storage for the grid and for electric vehicles. Other storage options are explored, including pumped and compressed air storage, flow batteries, and using electricity to heat or cool water or to generate a combustible fuel (power-to-gas), such as hydrogen, which can be used to provide heat sustainably.
Self-reported Age of Hypertension Onset and Hypertension-Mediated Organ Damage in Middle-Aged Individuals
Authors: Suvila Karri , McCabe Elizabeth L , Lima Joao A C , Aittokallio Jenni , Yano Yuichiro , Cheng Susan , Niiranen Teemu J 
Published: March 2020

Abstract

Background
Objectively defined early onset hypertension, based on repeated blood pressure measurements, is a strong risk factor for cardiovascular disease (CVD). We aimed to assess if also self-reported hypertension onset age is associated with hypertension-mediated organ damage (HMOD). Additionally, we evaluated the agreement between self-reported and objectively defined hypertension onset age.

Methods
We studied 2,649 participants (50 ± 4 years at the time of outcome assessment, 57% women) of the Coronary Artery Risk Development in Young Adults (CARDIA) study who underwent measurements for echocardiographic left ventricular hypertrophy (LVH), left ventricular diastolic dysfunction (LVDD), coronary calcification, and albuminuria. We divided the participants into groups according to self-reported hypertension onset age (&lt;35 years, 35–44 years, ≥45 years, and no hypertension). We used multivariable-adjusted logistic regression models to assess the relation between self-reported hypertension onset age with the presence of HMOD, with those who did not report hypertension as the referent group.

Results
Compared with individuals without self-reported hypertension, self-reported hypertension onset at &lt;35 years was associated with LVH (odds ratio (OR), 2.38; 95% confidence interval (CI), 1.51–3.76), LVDD (OR, 2.32; 95% CI, 1.28–4.18, coronary calcification (OR, 2.87; 95% CI, 1.50–5.47), and albuminuria (OR, 1.62; 95% CI, 0.81–3.26). Self-reported hypertension onset at ≥45 years was only associated with LVDD (OR, 1.81; 95% CI, 1.06–3.08). The agreement between self-reported and objectively defined hypertension onset age groups was 78–79%.

Conclusions
Our findings suggest that self-reported hypertension onset age, a pragmatically feasible assessment in clinical practice, is a reasonable method for assessing risk of HMOD and CVD.
Indigenous Destinies
Authors: Cox James H 
Published: March 2020

Abstract
Gerald Vizenor displays his playful wit and provocative theorizing of Indigenous creativity in Native Provenance (2019), a collection of essays adapted from material that appeared in other forms between 2004 and 2019. He uses familiar concepts (survivance, transmotion, gossip theory) to drive discussions of familiar topics (World War I veterans from White Earth, the White Earth constitution, Indigenous abstract expressionist painters). Devoted readers of Vizenor will appreciate but also wonder about the persistence in his work over many decades of certain topics and critical emphases. A decreased interest in crossbloods as trickster figures represents one of the most significant shifts in emphasis from the middle to the later part of Vizenor’s career. Louis Owens admired Vizenor’s work on crossbloods, and he lived an experience fundamental to his view of the world that he called, similarly, “mixedblood.” Yet, as many of the contributors to Louis Owens: Writing Land and Legacy (2019) demonstrate, Owens consistently recognized distinct Native and non-Native worlds in his scholarship and drew upon tribal nation-specific beliefs and practices in his novels. His characters often struggled to understand their connection to Indigenous histories, communities, and families, all of which Owens valued, even when they remained inaccessible, either to him or his characters.
Safe Composite Calf Augmentation: A Staged Procedure
Authors: Andjelkov Katarina , Atanasijevic Tatjana C , Popovic Vesna M , Colic Milan , Llull Ramon 
Published: March 2020

Abstract

Background
Calf augmentation can be achieved by fat grafting, calf implants, or a combination of both methods (composite augmentation). For safety reasons, it is important to be aware of important calf anatomic features, specific physiologic considerations, and some health conditions that can hinder the outcome of these procedures.

Objectives
The aim of this study was to present our experience with performing composite calf augmentation, and to describe indications, surgical techniques and safety issues.

Methods
We retrospectively analyzed 63 patients who had undergone composite calf augmentation for cosmetic and reconstructive surgery in our practice. We reviewed group demographics, complications, and results, and identified all the pitfalls encountered in our cases. Additionally, dissection of the calf regions in fresh cadavers was performed to obtain more accurate anatomy. We also measured intracompartmental pressures before and after calf augmentation with implants in 6 cases to determine pressure changes.

Results
All cases received subfascial implant insertion and fat grafting as a delayed procedure. If there is a need for multiple implants, we recommend a staged procedure. Our study showed high muscle sensitivity to pressure increase after augmentation. Hence, from the standpoint of safety, we advocate subcutaneous fat grafting only. No patients developed compartment syndrome.

Conclusions
Composite calf augmentation surgery is safe and easy to reproduce, with a short recovery period and a low complication rate when done as a staged procedure and respecting specific anatomic and physiologic calf features.

Level of Evidence: 4
Histological Evaluation of the Skin After Fat Grafting: A Blinded, Randomized, Controlled Clinical Study
Authors: Maricevich Juan P B R , Lima Marcel F M B , Maricevich Ana Carolina , Maricevich Marco A B R , Silva Larissa F J , Takano Daniela M , Anlicoara Rafael , Ferraz Álvaro Antônio Bandeira 
Published: March 2020

Abstract

Background
Autologous fat graft is often employed to treat body contour defects. There is currently increased interest in the regenerative properties of fat grafting.

Objectives
The authors evaluated the histological changes of fat grafting in a blinded randomized controlled trial of staged fat grafting-abdominoplasty.

Methods
Ten women between 24 and 55 years of age with a body mass index &lt;30 kg/m2 and previous cesarean scar were submitted to fat grafting followed by staged abdominoplasty. The C-section scar served as a landmark for standardization of fat grafting site and control. One side of the abdomen was fat grafted and the other was left intact (control). At the time of abdominoplasty, 4 months later, a full-thickness skin sample from each hemi abdomen (fat-grafted area and control) was collected and sent to histological analysis.

Results
All of the fat-grafted samples showed extracellular lipids and signs of fat graft viability, whereas no such changes occurred in the control group. There were no statistically significant differences in fat-grafted vs control samples regarding skin inflammatory infiltrate (P = 0.582), dermis thickness (P = 0.973), vascular density (P = 0.326), and amount of elastic fibers (P = 1).

Conclusions
The histological evaluation of women’s abdominoplasty surgical site skin after 4 months of fat grafting showed signs of fat graft in 100% of the grafted sides but no change in skin inflammatory infiltrate, dermis thickness, vascularity density, or elastic fiber quantity.
The Traditional or Reverse Algorithm for Diagnosis of Syphilis: Pros and Cons
Authors: Ortiz Daniel A , Shukla Mayur R , Loeffelholz Michael J 
Published: March 2020

AbstractWe reviewed relevant syphilis diagnostic literature to address the question “What diagnostic considerations should be taken into account when screening for syphilis using the traditional or reverse algorithm?” Improved laboratory diagnosis of syphilis is an important element of the effort to reduce syphilis rates. Screening for syphilis is performed using either a nontreponemal or treponemal test (part of the traditional or reverse algorithm, respectively). Both syphilis algorithms are used by laboratories. However, there are limited data on the performance and cost-effectiveness of the algorithms. An expert panel generated “key questions” in the laboratory diagnosis of syphilis. This paper pertains to the key factors that should be considered when deciding whether to screen for syphilis using either the traditional or the reverse algorithm. A systematic literature review was performed, and tables of evidence were created to address this question.
Resist the Temptation of Response-Adaptive Randomization
Authors: Proschan Michael , Evans Scott 
Published: March 2020

AbstractResponse-adaptive randomization (RAR) has recently gained popularity in clinical trials. The intent is noble: minimize the number of participants randomized to inferior treatments and increase the amount of information about better treatments. Unfortunately, RAR causes many problems, including (1) bias from temporal trends, (2) inefficiency in treatment effect estimation, (3) volatility in sample-size distributions that can cause a nontrivial proportion of trials to assign more patients to an inferior arm, (4) difficulty of validly analyzing results, and (5) the potential for selection bias and other issues inherent to being unblinded to ongoing results. The problems of RAR are most acute in the very setting for which RAR has been proposed, namely long-duration “platform” trials and infectious disease settings where temporal trends are ubiquitous. Response-adaptive randomization can eliminate the benefits that randomization, the most powerful tool in clinical trials, provides. Use of RAR is discouraged.
Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry
Authors: Boyer Annabel , Lanot Antoine , Lambie Mark , Guillouet Sonia , Lobbedez Thierry , Béchade Clémence 
Published: March 2020

Abstract

Background
There is limited information available on the use of assisted peritoneal dialysis (PD) over time and the impact of economic incentives on its utilization. The aim of this study was to describe the trends in assisted PD utilization and the type of assistance provided. We wanted to estimate if an economic incentive implemented in 2011 in France was associated with an increase in the utilization of nurse-assisted PD.

Methods
This retrospective, multicentre study, based on data from the French Language Peritoneal Dialysis Registry, analysed 11 987 patients who initiated PD in France between 1 January 2006 and 31 December 2015. Adjusted Cox regression with robust variance was used to examine the initiation of assisted PD, both nurse-assisted and family-assisted, accounting for the nonlinear impact of the PD starting time.

Results
There were 6149 (51%) incident patients on assisted PD, 5052 (82%) on nurse-assisted PD and 1097 (18%) on family-assisted PD over the study period. In the adjusted analysis, calendar time was associated with the assisted PD rate: it declined from 2008 until 2013 before flattening out and then it increased after 2014. Nurse-assisted PD utilization increased significantly after 2012, whereas family-assisted PD utilization decreased linearly over time (prevalence ratio = 0.94, 95% confidence interval 0.92–0.97).

Conclusions
The assisted PD rate decreased until 2013, mainly because of a decline in family-assisted PD. The uptake in nurse-assisted PD observed from 2013 reflects the effect of an economic incentive adopted in late 2011 to increase PD utilization.
2015 Guidelines for Cardiopulmonary Resuscitation and survival after adult and paediatric out-of-hospital cardiac arrest
Authors: Granfeldt Asger , Holmberg Mathias J , Donnino Michael W , Andersen Lars W ,   CARES Surveillance Group
Published: March 2020

Abstract

Aims
To evaluate whether the introduction of the 2015 Guidelines for Cardiopulmonary Resuscitation were associated with a change in outcomes after out-of-hospital cardiac arrest (OHCA).

Methods and results
Patients with OHCA were divided into adults (≥18 years) and paediatric cases (&lt;18 years). An interrupted time-series analysis was used to compare survival before (pre-guidelines 1 January 2013 to 31 October 2015) and after (post-guidelines 1 May 2016 to 31 December 2018) introduction of the 2015 guidelines. We fitted a regression model after dividing the time-period into segments with separate intercept and slope estimates. We included 309 499 adults and 8668 children with OHCA. There was no difference in the change in survival to hospital discharge with a favourable functional outcome per year between the two periods for adults {slope difference: −0.07% [95% confidence interval (CI) −0.30 to 0.16], P = 0.55} and paediatric cases [slope difference: −0.01% (95% CI −1.35 to 1.32), P = 0.98]. Likewise, we found no immediate change in survival to hospital discharge with a favourable functional outcome between the two periods for adults [0.20% (95% CI −0.21 to 0.61), P = 0.33] and paediatric cases [−1.08 (95% CI −3.44 to 1.27), P = 0.37].

Conclusion
Publication of the 2015 Guidelines for Cardiopulmonary Resuscitation was not associated with an increase in survival to hospital discharge with a favourable functional outcome after OHCA. Outcomes for OHCA have not improved the last 6 years in the USA.
Rapid two-stage Starnes approach in high-risk neonates with Ebstein anomaly
Authors: Asou Toshihide , Kawataki Motoyoshi , Takeda Yuko , Asai Hidetsugu , Tachibana Tsuyoshi , Toyoshima Katsuaki , Kim Ki-Sung , Ueda Hideaki 
Published: March 2020

Abstract

OBJECTIVES
The purpose of this study is to review the short- and long-term outcomes of high-risk neonates with Ebstein anomaly treated with a newly developed rapid 2-stage Starnes procedure, which is aimed at reducing the size of the enlarged right side of the heart.

METHODS
Fifty-two foetuses with Ebstein anomaly were analysed in this study and divided into 2 groups. The control group comprised 25 foetuses, referred to us before 2008, and the study group was composed of 27 foetuses, referred to us after 2009. The right atrial area index was defined as high risk when it was &gt;1.5. We applied our management approach to 6 high-risk neonates in the study group. This approach consisted of reducing the size of the right side of the heart through a 2-stage process: (i) right atrial plication without the use of a bypass and (ii) a Starnes procedure. Cox proportional hazards models were used to evaluate the effects of our management approach on the survival rates of the neonates.

RESULTS
The mean follow-up period was 7.5 ± 3.3 years. All 6 high-risk neonates in the study group survived. The overall hazard ratio was 0.12 (95% confidence interval of 0.03–0.43) in the study group as compared with the control group (P = 0.0007). A Fontan operation was completed in all but 1 case, with the remaining case awaiting a Fontan operation.

CONCLUSIONS
We suggest that a rapid 2-stage Starnes approach can be effective in the treatment of high-risk neonates with Ebstein anomaly.
Individualized Relationship Practices and Union Dissolution: Differences Between Marriage and Cohabitation
Authors: Hiekel Nicole , Wagner Michael 
Published: March 2020

AbstractEmotional disclosure, self-determination and egalitarianism are considered central benefits of individualized relationships. Yet, the body of research linking relationship practices and union stability is sparse. We study the extent to which relationship practices in the spheres of intimacy, autonomy, and democracy affect the risk of union dissolution, comparing marriage and cohabitation. Using longitudinal data from nine waves of the German Pairfam survey, we predict union dissolution of n = 3,650 cohabiting and married women and men. Cohabiters report higher levels of individualized relationship practices compared to the married. Intimacy is the key dimension predicting union stability. Individuals thus exhibit relatively low resilience towards decline in emotional gratification in their couple relationships. Autonomy and democracy are not empirically relevant to predict union stability beyond the extent to which they were connected to levels of intimacy. Differences between cohabitation and marriage were marginal with spouses’ benefits from higher levels of intimacy for union stability being larger compared to cohabiting individuals. Our study contributes to the analytical clarification of the consequences of the changing meaning of intimate relationships in individualized societies, and ultimately, to cultural explanations for increased relationship instability.
Understanding seismic path biases and magmatic activity at Mount St Helens volcano before its 2004 eruption
Authors: Gabrielli S , De Siena L , Napolitano F , Del Pezzo E 
Published: March 2020

SUMMARYIn volcanoes, topography, shallow heterogeneity and even shallow morphology can substantially modify seismic coda signals. Coda waves are an essential tool to monitor eruption dynamics and model volcanic structures jointly and independently from velocity anomalies: it is thus fundamental to test their spatial sensitivity to seismic path effects. Here, we apply the Multiple Lapse Time Window Analysis (MLTWA) to measure the relative importance of scattering attenuation vs absorption at Mount St Helens volcano before its 2004 eruption. The results show the characteristic dominance of scattering attenuation in volcanoes at lower frequencies (3–6 Hz), while absorption is the primary attenuation mechanism at 12 and 18 Hz. Scattering attenuation is similar but seismic absorption is one order of magnitude lower than at open-conduit volcanoes, like Etna and Kilauea, a typical behaviour of a (relatively) cool magmatic plumbing system. Still, the seismic albedo (measuring the ratio between seismic energy emitted and received from the area) is anomalously high (0.95) at 3 Hz. A radiative-transfer forward model of far- and near-field envelopes confirms this is due to strong near-receiver scattering enhancing anomalous phases in the intermediate and late coda across the 1980 debris avalanche and central crater. Only above this frequency and in the far-field diffusion onsets at late lapse times. The scattering and absorption parameters derived from MLTWA are used as inputs to construct 2-D frequency-dependent bulk sensitivity kernels for the S-wave coda in the multiple-scattering (using the Energy Transport Equations—ETE) and diffusive (AD, independent of MLTWA results) regimes. At 12 Hz, high coda-attenuation anomalies characterize the eastern side of the volcano using both kernels, in spatial correlation with low-velocity anomalies from literature. At 3 Hz, the anomalous albedo, the forward modelling, and the results of the tomographic imaging confirm that shallow heterogeneity beneath the extended 1980 debris-avalanche and crater enhance anomalous intermediate and late coda phases, mapping shallow geological contrasts. We remark the effect this may have on coda-dependent source inversion and tomography, currently used across the world to image and monitor volcanoes. At Mount St Helens, higher frequencies and deep borehole data are necessary to reconstruct deep volcanic structures with coda waves.