bluuebunny/crossref_metadata_2025_split huggingface dataset:
The DEDO Forest Conservation Culture a Means to Conserves the Ororo (Ekebergia Capensis) Tree.
Authors: Shoddo Getaneh Haile 
Published: October 2020

Abstract
BackgroundThe forest people around the world through their indigenous knowledge contribute to the sustainable management of forests. This article argues that the Sheka people in southwestern Ethiopia by their ecological knowledge, values, and spiritual use could manage the Ororo tree (Ekebergia capensis). The Ororo tree (Ekebergia capensis) is one of the most important endemic tree species in the Sheka zone southwestern Ethiopia and, at the same time, one of the most endangered species. MethodsData collected on the indigenous ecological knowledge of the Sheka people and how the Ororo tree could be managed and conserved through the DEDO culture documented and the spiritual connection between the Ororo trees and the Sheka people traditional belief system measured. ResultsThe findings revealed that through their traditional forest-related knowledge, the Sheka people conserve and manage a single larger tree called Ororo. The Ororo tree is a special type of tree that has cultural and spiritual attachments that are presently non-existent. This unique forest conservation practice has been referred to as the DEDO culture. Thus, The culture of DEDO described in this article shows that it still exists in every element of local forest protection, and management Ororo tree (Ekebergia capensis). As the study clearly shows, the DEDO culture is productive and efficient for forest management, and this useful culture has demonstrated its significance in the protection of various forest types and tree species, contributing to the conservation of biodiversity.ConclusionThus, The culture of DEDO described in this article shows that it still exists in every element of local forest protection, and management Ororo tree (Ekebergia capensis). As the study clearly shows, the DEDO culture is productive and efficient for forest management, and this useful culture has demonstrated its significance in the protection of various forest types and tree species, contributing to the conservation of biodiversity.
Artificial Neural Network Model to Predict Post-Hepatectomy Early Recurrence of Hepatocellular Carcinoma without Macroscopic Vascular Invasion
Authors: Mai Rong-yun , M.M. Jie Zeng , Meng M.M. Wei-da , Lu Hua-ze , Liang Rong , Lin Yan , Wu Guo-bin , Li Le-qun , Ma Liang , Ye Jia-zhou , Bai Tao 
Published: October 2020

Abstract
Background: The accurate prediction of post-hepatectomy early recurrence (PHER) for hepatocellular carcinoma (HCC) is of great significance in determining postoperative adjuvant treatment and monitoring. This research aimed to develop and validate an artificial neural network (ANN) model to predict PHER in HCC patients without macroscopic vascular invasion.Methods: 903 patients who underwent curative liver resection for HCC were collected. They were randomly divided into a derivation cohort (n = 679) and a validation cohort (n = 224). The ANN model was then developed in the derivation cohort and verified in the validation cohort.Results: The morbidity of PHER in the derivation and validation cohorts was 34.8% and 39.2%, respectively. Multivariate analysis revealed that hepatitis B virus DNA load, γ-glutamyl transpeptadase, α-fetoprotein, tumor diameter, tumor differentiation, microvascular invasion, satellite nodules and blood loss were significantly associated with PHER. Incorporating these factors, the ANN model had greater discriminatory abilities than conventional Cox model, existing recurrence models and commonly used staging systems for predicting PHER. Stratification into two risk groups indicated a statistically significant discrepancy in recurrence-free survival curves. Conclusion: The ANN model has a significant advantage in predicting PHER for HCC patients without macroscopic vascular invasion when compared to other models and staging systems.
Usefulness of Monitoring Circulating Tumor Cells as a Therapeutic Biomarker in Melanoma with BRAF Mutation
Authors: Okuyama Ryuhei , Kiniwa Yukiko , Nakamura Kenta , Mikoshiba Asuka , Ashida Atsuko , Akiyama Yasuyuki , Morimoto Atsushi 
Published: October 2020

Abstract
Background: Circulating tumor cells (CTCs) are non-invasive biomarkers that could be used to characterize changes in tumors. In this study, we monitored the number of CTCs, as well as the BRAF genotype of individual CTCs. Methods: CTCs were isolated from peripheral blood using a high-density dielectrophoretic microwell array, followed by labeling with melanoma-specific markers (MART-1 and/or gp100) and a leukocyte marker (CD45). Results: Examination of patients with stage 0–III melanoma detected CTCs even in patients with early disease (stage 0 or I). Next, we analyzed CTCs in five patients with stage IV melanoma during treatment with BRAF/MEK inhibitors. The number of CTCs fluctuated in association with the drug response in four of the five patients, suggesting that the total number of CTCs usually reflected the drug response. Interestingly, one of those patients had CTCs with seven different BRAF genotypes, and the mutated CTCs disappeared upon treatment with BRAF/MEK inhibitors, except for those harboring BRAFA598V.Conclusions: CTCs are present even in the early stage of melanoma, and the number of CTCs seems to reflect drug response during treatment with BRAF/MEK inhibitors. Furthermore, genetic heterogeneity of BRAF may contribute to drug resistance of BRAF/MEK inhibitor. Our findings demonstrate the usefulness of CTC analysis in melanoma for monitoring targeted therapies and understanding mechanism of drug resistance.
Risk factors of mortality for intensive care COVID-19 patients: A retrospective cohort study.
Authors: Gu Yanli , Wang Donghui , Chen Cen , Lu Wanjun , Liu Hongbing , Lv Tangfeng , Song Yong , Zhang Fang 
Published: October 2020

Abstract
Aims: To identify the risk factors of mortality for coronavirus disease 19 (COVID-19) patients admitted to intensive care units (ICU), we conducted a retrospective analysis.Methods: The demographic characteristics, laboratory findings and chest X-ray data of COVID-19 patients admitted to ICU of Huoshenshan Hospital from February 10 to April 10, 2020 were retrospectively analyzed. Student's t test and chi-square test were used to compare continuous variables, categorical variables respectively. Logistic regression model was used to seek risk factors of mortality.Results: A total of 57 patients (38 males and 19 females) were included in this retrospective study, including 20 patients in deceased group and 37 patients in surviving group. Leukocyte count, neutrophil count, lymphocyte count, eosinophil count, neutrophil-to-lymphocyte ratio (NLR), urea nitrogen, lactate dehydrogenase (LDH), interleukin-6 (IL-6), C-reactive protein (CRP), arterial partial pressure of oxygen/oxygen concentration (PaO2/FiO2) and imaging findings were statistically different between the two groups. The multivariate logistic regression analysis identified IL-6 and PaO2/FiO2 as independent risk factors of mortality. The area of under curves (AUC) of IL-6 and PaO2/FiO2 were 0.9 (95%CI:0.823-0.977, p<0.0001) and 0.865 (95%CI:0.774-0.956, p<0.0001) respectively. The cut-off value of IL-6 was 25.69 pg/mL, the sensitivity was 95% and the specificity was 75.7%, while the cut-off value of PaO2/FiO2 was 167.79 mmHg, the sensitivity was 75.7% and the specificity was 85%.Conclusion: Clinicians should pay enough attention to IL-6 and PaO2/FiO2, especially when IL-6>25.69 pg/ml and PaO2/FiO2<167.79 mmHg, and take active intervention measures as early as possible.
Benchmarking the efficiency of a metamodeling-enabled algorithm for the calibration of surface water quality models
Authors: Kandris K. , Romas E. , Tzimas A. 
Published: October 2020

Abstract
Computational efficiency is a major obstacle imposed in the automatic calibration of numerical, high-fidelity surface water quality models. To surpass this obstacle, the present work formulated a metamodeling-enabled algorithm for the calibration of surface water quality models and assessed the computational gains from this approach compared to a benchmark alternative (a derivative-free optimization algorithm). A radial basis function was trained over multiple snapshots of the original high-fidelity model to emulate the latter's behavior. This data-driven proxy of the original model was subsequently employed in the automatic calibration of the water quality models of two water reservoirs and, finally, the computational gains over the benchmark alternative were estimated. The benchmark analysis revealed that the metamodeling-enabled optimizer reached a solution with the same quality compared to its benchmark alternative in 20–38% lower process times. Thereby, this work manifests tangible evidence of the potential of metamodeling-enabled strategies and sets out a discussion on how to maximize computational gains deriving from such strategies in surface water quality modeling.
Using corncob-based biochar to intercept BTEX in stormwater filtration systems
Authors: Wang Huannan , Yan Dandan , Zeng Huan , He Jiajie 
Published: October 2020

Abstract
A biochar material made from corncobs was tested for its capability in BTEX adsorption/interception in stormwater filtration systems. Batch experiments were conducted to examine the adsorption kinetics, adsorption isotherms, and adsorption thermodynamics of BTEX onto this biochar. The feasibility of applying this biochar in stormwater filtration was studied by dynamic transport experiments and model simulations. The result showed that this biochar can adsorb BTEX and the adsorption is a thermodynamically spontaneous, and endothermic process. The BTEX adsorption kinetic experiment and adsorption retarded BTEX transport experiment indicated that the BTEX adsorption kinetics can be changed by the driving force between the BTEX concentrations and the active adsorption site as well as the contact time between BTEX and the biochar. In terms of applying this biochar in stormwater filtration, the Monte Carlo uncertainty analysis indicated that the BTEX interception is sensitive to the hydraulic conductivity of the biochar filter and the adsorption kinetics of the biochar material. Although this corncob-made biochar demonstrated effective pollutant adsorption capability, the biochar adsorption capability should be utilized to retain the pollutant long enough for biodegradation to take effect for ultimate pollutant attenuation.
Nitrate removal from aqueous solutions by cobalt ferrite nanoparticles synthesized by co-precipitation method: isotherm, kinetic and thermodynamic studies
Authors: Kamranifar Mohammad , Naghizadeh Ali , Masoudi Fatemehsadat , Osmani Farahnaz , Davoodi Maryam , Nabavian Mohammad Reza 
Published: October 2020

AbstractThe purpose of this study was to examine the nitrate adsorption by cobalt ferrite (CFO) nanoparticles. The adsorbent was synthesized by co-precipitation method and its structure was characterized using scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and vibrating-sample magnetometry. In batch adsorption studies, the effects of various parameters like pH (3–11), adsorbent dose (0.2–0.8 g/L), contact time (5–120 min), initial nitrate concentration (50–200 mg/L), and temperature (283–313 K) on the adsorption process were examined. The results of this study indicated that the maximum adsorption capacity was 107.8 mg/g (optimum condition pH = 3, adsorbent dosage: 0.2 g/L, nitrate concentration: 200 mg/L, contact time: 20 min and temperature: 313 K). The adsorption isotherm had a proper match with Langmuir (R2 = 0.99) and Freundlich (R2 = 0.99) models. The adsorption of nitrate by CFO followed pseudo-second-order kinetics. The results of the thermodynamics of the nitrate adsorption process by CFO showed that all the values of Gibbs free energy change, enthalpy change and entropy change were positive. Therefore, this process was endothermic and non-spontaneous.
A Cationic Gallium Phthalocyanine Inhibits Amyloid β Peptide Fibril Formation
Authors: Tabassum Shatera , Sheikh Abdullah Md. , Yano Shozo , Ikeue Takahisa , Mitaki Shingo , Michikawa Makoto , Nagai Atsushi 
Published: October 2020

Background:
Amyloid β (Aβ) peptide deposition is considered as the main cause of Alzheimer’s
disease (AD). Previously, we have shown that a Zn containing neutral phthalocyanine (Zn-Pc)
inhibits Aβ fibril formation.

Objective:
The objective of this study is to investigate the effects of a cationic gallium containing Pc
(GaCl-Pc) on Aβ fibril formation process.

Methods and Results:
Aβ fibril formation was induced by incubating synthetic Aβ peptides in a fibril
forming buffer, and the amount of fibril was evaluated by ThT fluorescence assay. GaCl-Pc dosedependently
inhibited both Aβ1-40 and Aβ1-42 fibril formation. It mainly inhibited the elongation phase of
Aβ1-42 fibril formation kinetics, but not the lag phase. Western blotting results showed that it did not inhibit
its oligomerization process, rather increased it. Additionally, GaCl-Pc destabilized preformed Aβ1-
42 fibrils dose-dependently in vitro condition, and decreased Aβ levels in the brain slice culture of APP
transgenic AD model mice (J20 strain). Near-infrared scanning results showed that GaCl-Pc had the
ability to bind to Aβ1-42. MTT assay demonstrated that GaCl-Pc did not have toxicity towards a neuronal
cell line (A1) in culture rather, showed protective effects on Aβ-induced toxicity. Moreover, it dosedependently
decreased Aβ-induced reactive oxygen species levels in A1 culture.

Conclusion:
Thus, our result demonstrated that GaCl-Pc decreased Aβ aggregation and destabilized the
preformed fibrils. Since cationic molecules show a better ability to cross the blood-brain barrier, cationic
GaCl-Pc could be important for the therapy of AD.
Developing Value Innovation Strategy In The "Blue Ocean Shift" Framework At The Flat Glass Industry In Indonesia
Authors: Subagio Rudy 
Published: October 2020

Competition in the flat glass market in Indonesia since 2015 has been increasingly severe because much imported glass has entered Indonesia. The rapid rate of imported glass is due to two factors: the enactment of the free trade pact in Southeast Asia and the expansion of the Chinese glass factory that built new factories in the Southeast Asia region, especially in Malaysia. Most of the imported glass entering Indonesia is commodity glass at a lower than local products, so they have begun to take a portion of the market share of local products. This competition is getting more onerous because the local flat glass industry has difficulties in reducing the price to be equal or lower than competitors' price due to the production cost structure is already too high. This research explores the basic concepts of strategies carried out by local flat glass companies in the face of competition in the flat glass industry. This is based on the concept of value innovation in the framework of “blue ocean shift.” The research method used is an exploratory case study draws on an in-depth field study conducted in a local flat glass company based in Indonesia.
John Saxe-Fernández (coordinador), Sociología política del colapso climático antropogénico. Capitalismo fósil, explotación de combustibles no convencionales y geopolítica de la energía
Authors: Sánchez Ricardo Carlos Alberto 
Published: October 2020

En 1960, el filósofo polaco Günther Anders publicó, por petición de sus alumnos, “Tesis para la Era Atómica” (Thesen zum Atomseitalket). Las “Tesis…” de Anders son el resultado de un seminario en la Universidad Libre de Berlín, realizado en 1959, cuya temática giró en torno a las implicaciones morales de la Era Atómica.Anders analizó los componentes morales, éticos y filosóficos de la era civilizacional, iniciada el 6 de agosto de 1945 en Hiroshima, caracterizada por un grado de desarrollo de la racionalidad hasta el punto de dar al ser humano la capacidad material de destruir a la humanidad, a la vida no humana e inclusive al planeta entero.
El procedimiento de la fuerza ficticia: un símil del método del potencial unidimensional equivalente en la solución del problema de Kepler
Authors: González Sierra Hernando , Toledo Chavarro Cristian Camilo 
Published: October 2020

Se elabora un procedimiento alternativo al del método del potencial unidimensional equivalente para describir las características cualitativas del movimiento de dos partículas bajo el efecto de fuerzas centrales, aplicándolo al caso específico del problema de Kepler relacionado con el movimiento de los planetas alrededor del sol; es decir, para la ley de fuerza atractiva inversamente proporcional al cuadrado de la distancia. El nuevo tratamiento denominado “Método de la fuerza ficticia” es implementado en el contexto de la Mecánica Clásica y difiere del método del potencial unidimensional equivalente a que en lugar de emplear el potencial ficticio se usa la fuerza ficticia; desde esta última perspectiva, se identifica que se está tratando con un símil, ya que se actúa en la misma área del conocimiento, y que se refiere a una nueva herramienta de características geométricas para obtener soluciones de tipo cualitativo a los efectos cinemáticos cuando se tienen fuerzas centrales entre dos cuerpos. El símil, para el caso particular tratado en el presente, conduce a los mismos resultados del método del potencial unidimensional equivalente, que proporciona secciones cónicas como trayectorias para la fuerza atractiva del cuadrado inverso entre los cuerpos, pero tiene la ventaja de que se pueden cuantificar los valores de la fuerza efectiva para algunas órbitas específicas. Al igual que el método del potencial unidimensional equivalente, el símil de la fuerza ficticia puede ser aplicado a otras leyes de fuerzas centrales de forma arbitraria y, lo más importante, el procedimiento podría mostrar su potencialidad en otras áreas de la física contemporánea, ciencias físicas y afines e ingenierías.
Local Wisdom in Designing Interior Design, Review of Cultural Arts and Design Style
Authors: Suroso Putro Tunjung Atmadi , Putra Yananto Mihadi , Ramadhan Ali 
Published: October 2020

Local wisdom is a system of values and norms that are arranged, practiced, understood and applied to local communities based on the understanding and their experience in interacting with the environment, in the development of interior design, local wisdom It can also be very instrumental in the design of interior design. Can collaborate on styles of interior design can be realized, it will be very interesting interior design, as well as safe, comfortable and harmonious. Based on the above, then the exposure in this study the author wanted to examine the application of the local wisdom in designing interior design that is associated with the development of the design. The methods used in this study is a qualitative descriptive method, approach to interior design pragmatically, topologies and have that is an important element in the design. The concept of Paul Laseau how to review the achievement of the concept of local wisdom applied in the process of designing the interior design. Special purpose to be achieved in this research is publication research and development results through on higher education, Journal of national and international journals. Expected in this research study is to apply the concept of local wisdom on designing the interior design, which is applied to the shaper of space.
Language Mastery of Refugee Children in Malaysia Despite Adverse Circumstances
Authors: Fernandez Aspin Janet , Cheong Loh Sau 
Published: October 2020

Refugee education is a challenge to the Malaysian government, with the ever rising influx of refugees into the country. Malaysia has policies in place whereby refugee children are not entitled or allowed an education in the government school system. They are encouraged to secure private education. The researcher was appointed as the external examiner for Year Six, the final year of Primary Education, whereby it was noted that a number of students had mastery of languages despite their adverse circumstances as refugee children. Eleven students from the refugee camp were randomly selected on the basis of anonymity. They were interviewed within a secure environment and this data was analysed along with the test answer scripts. The study seeks to explore plausible reasons for their language mastery despite adverse circumstances and offers insights for the findings to be applied within a local context where English is taught as a second language. Key words: refugee, education, mastery, languages
Rancang Bangun Kontrol Smart Parking Otomatis Berbasis Arduino
Authors: Salamah Ketty Siti , Putra Dolly Lovfinha 
Published: October 2020

Seiring dengan pertumbuhan kendaraan bermotor dan tidak seimbang antara pertumbuhan kendaraan dengan lahan parkir yang tersedia, hal ini terlihat dengan semakin menyempitnya fasilitas tersebut khususnya ditempat tempat keramaian seperti pasar, rumah sakit, pertokoan, perkantoran, dan juga tempat-tempat pendidiakan, kasus ini sering terjadi pada kota-kota yang sudah padat akan penduduknya serta tinggi kerapatan bangunannya. Smart Parking merupakan suatu sistem yang tepat untuk mengatasi permasalahan tersebut khususnya untuk smart parking bertingkat. Otomatisasi yang diterapkan pada sistem parkir ini menggunakan metode kontrol otomatis berupa arduino uno sebagai pusat sistemnya yang akan mengatur proses sistem parkiran mulai dari mobil masuk sampai mobil keluar area parkiran. Smart parking ini terdiri dari potensiometer yan berfungsi untuk menentukan posisi dari setiap slot parkir dan keypad yang digunakan untuk input user ID (Password) setiap pengguna yang sebelumnya sudah didaftarkan kedalam sistem sehingga tingkat keamanannya cukup baik
Acción directa: una plaza de nadie y de todos
Authors: Álvarez Pedrosian Eduardo , Vigo Denise Ivette 
Published: October 2020

Resumen: En este artículo nos sumergimos en una experiencia urbana particularmente interesante, en tanto es resultado de una experimentación colectiva: una plaza creada sobre las ruinas de un predio en una esquina de Montevideo por parte de un grupo autodefinido como anarquista. En primer término hacemos una introducción para contextualizar la aproximación etnográfica en la investigación mayor dentro de la cual se llevó a cabo, referida a las formas de habitar contemporáneas en los territorios del histórico segundo ensanche de Montevideo, el que consideramos como un laboratorio de exploración antropológica. Posteriormente presentamos el caso desde las concepciones y prácticas de ocupación anarquista, desde el devenir que nos lleva de las ruinas a su “recuperación” para la ciudad. Luego, problematizamos la noción de “acción directa” y las alternativas frente a la precariedad del habitar urbano, para llegar a analizar el fenómeno en los términos de las fuerzas que movilizan estos colectivos desde el anonimato en el diseño de espacialidades disruptivas. Palabras clave: Etnografía urbana. Anarquismo. Intervención urbana. Plaza. Esquina. DIRECT ACTION: A SQUARE OF NOBODY AND EVERYONEAbstract: In this paper we immerse ourselves in a particularly interesting urban experience, as it is the result of collective experimentation: a square created on the ruins of a building in a corner of Montevideo by a group that defined itself as an anarchist. Firstly, we make an introduction to contextualize the ethnographic approach in the major research within which it was carried out, referring to contemporary ways of dwelling in the territories of the historic second enlargement of Montevideo, which we consider as an anthropological laboratory for exploration. Later we present the case from the conceptions and practices of anarchist “occupation”, from the becoming that takes us from the ruins to its “recovery” for the city. Then, we problematized the notion of “direct action” and the alternatives to the precariousness of urban dwell, in order to analyze the phenomenon in terms of the forces that these groups mobilize from anonymity in the design of disruptive spatialities.Keywords: Urban ethnography. Anarchy. Urban intervention. Square. Street corner.