bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radon concentration measurement and effective dose assessment in different brands of commercial bottled water produced in China
Authors: Yong Jinlong , Feng Guangwen , Liu Qian , Tang Chao , Wu Baoshan , Hu Youhua , Cai Changlong , Mao Peihong 
Published: April 2020

Abstract
Radon and its progeny often exist in daily drinking water, and may pose a potential health threat to the public. In this study, the radon concentrations of 15 different brands of bottled drinking water and their radiological hazards were measured and evaluated. The results indicate that the concentration range of radon in water is 13.3 ± 4.7 to 300.0 ± 21.6 mBq/L, and is lower than the limit level (11.11 Bq/L). The results compared with radon concentrations from other countries or regions show that the radon concentrations in this study are almost within the range of those of all the others. The average annual effective dose for infants, children and adults in the three age-groups is 0.657, 0.535 and 0.665 μSv/y respectively, which is lower than the recommended level of 0.1 mSv/y. The results also show that the bottled water does not pose a major health hazard to the public. Moreover, combined with statistical analysis, it is concluded that the concentration of total dissolved solids (TDS) and Ca2+ in bottled mineral water has a strong correlation with the radon concentration in the water.
Methodological Features of GDP Formation Within the Framework of the System of National Accounts
Authors: Alekseev K. A. 
Published: April 2020

Purpose of the study. The aim of this work is to examine methodological approaches to the formation of gross domestic product on an annual and quarterly basis within the framework of the System of National Accounts, using the example of 189 countries. The work is based on a dynamic and structural analysis of statistical information of gross domestic product published on the official websites of statistical agencies and the International Monetary Fund.Materials and methods. The information base of the study is the official statistical data of countries published on the website of the International Monetary Fund, as well as methodological provisions for the formation of gross domestic product. The research methodological base is represented by statistical methods of information analysis and empirical research.Results. The analysis of data and methodological approaches to gross domestic product formation in different countries has been carried out, as a result of which the main problems of a number of countries regarding the accuracy and relevance of gross domestic product data have been identified. These problems are grouped into six key criteria based on practical macroeconomic approaches, in particular gross domestic product: updating of the base year, annual and quarterly gross domestic product data, timeliness of reporting gross domestic product data, method of compiling gross domestic product (production, expenditure, income), use of the international standard “System of national accounts, 2008”.Conclusion. Despite a rather large volume of macroeconomic indicators, one of the main indicators is gross domestic product, the dynamics of which reflects the development of the economy. Therefore, reliable data on gross domestic product play a key role in the analysis of macroeconomic and financial policies, as well as in the analysis and accuracy of forecasting the development of the country’s economy. The study revealed that 50% of the countries surveyed had acceptable base years, meaning that the transition to the new base year did not exceed 10 years. Virtually all countries generate annual gross domestic product data, while quarterly estimates of gross domestic product form about 65% of countries. The timeliness of data dissemination also varies from country to country, and many do not publish date information. 72% surveyed countries provide annual gross domestic product data in a timely manner, while 55% surveyed countries provide quarterly gross domestic product data in a timely manner. The production method is the most common of the three methods of calculating gross domestic product (the production method, the method of using income and the generation of gross domestic product by source of income). Gross domestic product formation in accordance with the current version of the international standard “System of National Accounts, 2008” is applied in 52% of countries, and in most other countries the previous version of the international standard “System of National Accounts, 1993” is used.
A violência institucional contra crianças, adolescentes e suas famílias: contexto histórico e perspectivas para a psicologia brasileira
Authors: Silva Flávio Joni Duarte , Andrade Maria Clara de Mello 
Published: April 2020

O presente artigo versa sobre a violência institucional contra a criança e o adolescente. Faz-se a tentativa, recorrendo a todo um aparato histórico, de mostrar que essas ações praticadas hoje, tem uma história e são herdeiras de outras ainda mais escancaradas e violentas. Em um primeiro momento vê-se a história das primeiras leis com o intuito de proteção das crianças e adolescentes, como algumas diretrizes do Código Penal de 1830 e a primeira lei brasileira que versava sobre diretrizes das vidas infantis, o Código de Menores. Na segunda parte, discorre-se sobre a reelaboração do Código Mello Matos e sobre o Estatuto da Criança e do Adolescente. Em sua terceira parte, o trabalho se dá em cima da questão do olhar psicológico e da prática da psicologia nestes locais de internação e reenquadramentos sociais. Será que estamos realmente fazendo nosso papel? Como guisa de conclusão, tenta-se verificar novas oportunidades para a psicologia, e discussões que ela deve ter consigo mesma para não cair em discursos que não são pertinentes e humanitários.
In Silico Analysis, Synthesis, and Biological Evaluation of Triazole Derivatives as H1 Receptor Antagonist
Authors: Badeliya Sandip N. , Panchal Ishan I. , Panigrahi Bibhuranjan , Patel C. N. 
Published: April 2020

Introduction:
Histamine, a biological amine, is considered as a principal mediator of
many pathological processes regulating several essential events in allergies and autoimmune diseases.
Numerous derivatives have been developed that strive with histamine at the H1 receptor
and prevent binding of histamine at the H1 receptor, thereby preventing allergic reactions. Molecules
containing a triazole ring fused with six-membered ring systems are found to possess broad
applications in the field of medicine and industry. The present study is an attempt to characterize
the impact of the nature of the substituent introduced at 5 positions of the-4H-1,2,4-triazole-3-thiol
on their capacities to bind with the H1 receptor.

Methods:
Molecular docking (PDB ID: 3RZE) revealed that synthesized derivatives and target
proteins were actively involved in binding with Tyr-108, Thr-112, Ala-216, and Phe-432 subunits.
A pharmacophore model, new 5-(4-substituted phenyl)-4-(phenylamino)-4-H-1,2,4-triazole-3-
thiols (5a-5h) were designed and evaluated for H1-blocking activity using isolated segments from
the guinea pig ileum.

Results:
According to in silico analysis, all the compounds have a topological polar
surface area (TPSA) less than 140 Å squared, so they tend to a good penetration in cell
membranes. The results show that most of the compounds are non-inhibitors of CYP450
substrates that play a fundamental role in drug metabolism. Compounds 5d
(50.53±12.03), 5h (50.62±12.33) and 7a (55.07±12.41) are more active than others.

Conclusion:
Finally, these derivatives were screened for H1 receptor antagonist activity
using guinea pig ileum taking chlorpheniramine maleate as a standard. Most of the
compounds possesses better antihistamine activity.
Identifying the Molecular Targets of an Anti-pathogenic Hydroalcoholic Extract of Punica granatum Peel Against Multidrug-resistant Serratia marcescens
Authors: Joshi Chinmayi , Patel Pooja , Godatwar Pawan , Sharma Sanjeev , Kothari Vijay 
Published: April 2020

Background:
Antibiotic-resistant members of the family Enterobacteriaceae are
among the serious threats to human health globally. This study reports the anti-pathogenic activity
of Punica granatum peel extract (PGPE) against a multi-drug resistant, beta-lactamase producing
member of this family i.e. Serratia marcescens.

Objective:
This study aimed at assessing the anti-pathogenic activity of PGPE against the gramnegative
bacterial pathogen S. marcescens and identifying the molecular targets of this extract in
the test bacterium.

Methods:
Effect of PGPE on S. marcescens growth and quorum sensing (QS)-regulated pigment
production was assessed through broth dilution assay. In vivo anti-infective and prophylactic activity
of PGPE was assessed employing the nematode worm Caenorhabditis elegans as a model
host. Differential gene expression in PGPE-exposed S. marcescens was studied through a whole
transcriptome approach.

Results:
PGPE was able to modulate QS-regulated pigment production in S. marcescens without
exerting any heavy growth-inhibitory effect at concentrations as low as ≥2.5 μg/mL. It could attenuate
the virulence of the test bacterium towards the worm host by 22-42% (p≤0.01) at even
lower concentrations (≥0.5 μg/mL). PGPE also exerted a post-extract effect on S. marcescens.
This extract was found to offer prophylactic benefit too, to the host worm, as PGPE-pre-fed
worms scored better (34-51%; p≤0.001) survival in face of subsequent bacterial attack. Differential
gene expression analysis revealed that PGPE affected the expression of a total of 66 genes in
S. marcescens by ≥1.5 fold.

Conclusion:
The anti-virulence effect of PGPE against S. marcescens is multifaceted, affecting
stress-response machinery, efflux activity, iron homeostasis, and cellular energetics of this bacterium
notably. Among the major molecular targets identified in this study are LPS export
transporter permease (LptF), t-RNA pseudouridine synthase (TruB), etc.
T9-T10 Osteomyelitis, Epidural Abscess and Cord Compression Secondary to Mycobacterium abscessus: A Case Report
Authors: Davis Michelle A. , Antony Suresh 
Published: April 2020

Case Report:We report a case of spinal abscess/osteomyelitis at the T9-T10 levels in a non-immunocompromised patient who presented with lower extremity weakness secondary to a Mycobacterium abscessus infection. This patient was successfully treated with surgical debridement with amikacin-tigecycline-imipenem triple therapy before and after her debridement. Outcomes and treatment with this rare cause of epidural abscess/osteomyelitis are not well defined at this time.Background:Clinical Presentations with this species of mycobacterium are usually systemic with patients presenting with pulmonary and soft tissue infections. The primary presentation of spinal epidural abscess/osteomyelitis is unusual, especially when there is no primary focus such as a lung infection or concurrent bacteremia.Conclusion:This paper presents a new case of spinal osteomyelitis without a primary source in addition to 10 previously reported M. abscessus cases. The treatment plans and outcomes suggest that surgical debridement along with a macrolide-based combination therapy should be considered a definitive treatment against Mycobacterium abscesses.
Review and Improvement of the Finite Moment Problem
Authors: Hjouj Fawaz , Jouini Mohamed Soufiane 
Published: April 2020

Background:
This paper reviews the Particle Size Distribution (PSD) problem in detail. Mathematically, the problem faced while recovering a function from a finite number of its geometric moments has been discussed with the help of the Spline Theory. Undoubtedly, the splines play a major role in the theory of interpolation and approximation in many fields of pure and applied sciences. B-Splines form a practical basis for the piecewise polynomials of the desired degree. A high degree of accuracy has been obtained in recovering a function within the first ten to fifteen geometric moments. The proposed approximation formula has been tested on several types of synthetic functions. This work highlights some advantages, such as the use of a practical basis for the approximating space, the exactness of computing the moments of these basis functions and the reduction of the size along with an appropriate transformation of the resulting linear system for stability.

Objective: The aim is to recover a function from a finite number of its geometric moments.

Methods: The main tool is the Spline Theory. Undoubtedly, the role of splines in the theory of interpolation and approximation in many fields of pure and applied sciences has been well- established. B-Splines form a practical basis for the piecewise polynomials of the desired degree.

Results: A high degree of accuracy has been obtained in recovering a function within the first ten to fifteen geometric moments. The proposed approximation formula is tested on several types of synthetic functions.

Conclusion: This work highlights some advantages, such as the use of a practical basis for the approximating space, the exactness of computing the moments of these basis functions and the reduction of the size along with the data transformation of the resulting linear system for stability.
Magnetic Resonance Imaging (MRI) findings of Cervical Spine Derangement (CSD) among Iraqi Working Dentists
Authors: Al Shammari Ghassan Abdulateef Abbas , Al-Esawi Sattar Razzaq , Taher Abbas , Albujeer Ammar H 
Published: April 2020

Objective:
To assess the cervical spine derangement among working dentists using MRI in order to establish a relationship between job parameters and cervical derangement changes.

Methods:
A cross-sectional study was carried out at the MRI unit of Al-Sader Medical city of Al Najaf health directorate from June 2015 to December 2016. The involved 43 working dentist volunteers of varying age and sex, who underwent an MRI of their cervical spine.

Results:
The MRI was normal in 16 (37.3%) and abnormal in 27 (62.8%) participants. The abnormality was due to cervical spine spondylitis changes.

Conclusion:
Intervertebral Discs (IVD) degeneration was the most frequent finding, followed by IVD herniation.
Assessment of Peri-implant Buccal Bone Thickness Using Digital Imaging Techniques: A Systematic Review and Meta-analysis
Authors: Bohner Lauren , Hanisch Marcel , Chilvarquer Israel , Kleinheinz Johannes , Tortamano Pedro 
Published: April 2020

Objectives:
This systematic review aimed to answer the following focused question: Do the currently available imaging techniques provide accuracy in the assessment of peri-implant buccal bone thickness?

Methods:
A search strategy was conducted in eight electronic databases, followed by an additional manual search in grey literature and references of selected articles. Studies evaluating the accuracy of imaging techniques to measure peri-implant buccal bone thickness were included. Individual risk of bias was assessed by the Quality Assessment Tool for Diagnostic Accuracy Studies-2 (QUADAS-2). Meta-analysis was performed to evaluate CBCT accuracy. The overall effect size was determined by means of the Z-test. Q test was used to evaluate the homogeneity of effect sizes among studies and I2 was applied to determine the variance within studies.

Results:
After an initial screening, 83 studies were further selected for full reading and 13 of them were considered eligible for this review. In sum, the accuracy of Cone-beam Computed Tomography (CBCT), of ultrasound, and of computed tomography were assessed. There was no statistically significant difference between CBCT and the gold standard (p=0.81). The mean difference between measurements of bone thickness obtained by CBCT and the goldstandard was -0.0.3mm [95%CI -0.29;0.253mm].

Conclusion:
CBCT showed acceptable accuracy for assessing peri-implant bone. No meaningful conclusion could be drawn about other techniques.
A New Study of Shape and Size-dependent Properties of Nanocrystals Utilizing the Fractional Fourier Transform
Authors: Salem Aeshah 
Published: April 2020

Background:
Possessions of components, described by their shape and
size (S&S), are certainly attractive and has formed the foundation of the developing
field of nanoscience.

Methods:
Here, we study the S&S reliant on electronic construction and possession
of nanocrystals by semiconductors and metals to explain this feature. We formerly
considered the chemical dynamics of mineral nanocrystals that are arranged
according to the S&S not only for the big surface area, but also as a consequence of
the considerably diverse electronic construction of the nanocrystals.

Results:
The S&S of models, approved by using the Fractional Fourier Transform
Infrared Spectroscopy (FFTIR), indicate the construction of CdSe and ZnSe
nanoparticles.

Conclusion:
In order to study the historical behavior of the nanomaterial in terms
of S&S and estimate further results, the FFTIR was used to solve this project.
The Quality of Life in Mothers of Children with Attention Deficit Hyperactivity Disorder: A Comparative Study in Tehran, Iran
Authors: Vafaee-Shahi Mohammad , Purfallah Mehrnoosh , Shirazi Elham , Noorbakhsh Samileh 
Published: April 2020

Background & Aim:
Attention deficit hyperactivity disorder (ADHD) is the most common mental
health disorder among young children that affects the mothers’ lifestyles The aim of the present study
was to consider the quality of life in Iranian mothers with ADHD children.

Objective:
In this comparative study, we compared the quality of life between mothers of ADHD
children and mothers of normal children.

Methods:
In this descriptive study (2018-2019), a total of 75 mothers with ADHD children and
75 mothers with normal children, who were referred to referral educational hospital (Rasoul Hospital;
Tehran, Iran) were evaluated. ADHD criteria were assessed by means of the SNAP-IV questionnaire,
while the quality of life was evaluated by the SF-36 questionnaire. All data were analyzed by SPSS
software. The environmental, mental, social physical, health and quality of life were compared
between 2 groups.

Results:
The economic situation of mothers with normal children was average (73.3%) to good
(16%), while in mothers with ADHD children the economic situation was average (45.3%) to poor
(37.3%). Mothers’ employment in normal children group was 41.3%, but it was 14.6% in mothers
with ADHD children. A significant difference was reported between two groups in the mean of environmental
health score (p<0.05), social relationships (p<0.05), mental health (p<0.05), physical
health (p<0.01) and quality of life (p<0.01). The mean score of environmental health, social relationships,
mental health, physical health and quality of life in ADHD mothers was significantly
lower than mothers with normal children.

Conclusion:
The difficulties in the management of ADHD children negatively affect the quality of
mothers’ lifestyles. Therefore, preventive, educational and therapeutic interventions are recommended
to improve the mental health and the quality of life of mothers.
Keefektifan pembelajaran berbasis proyek ditinjau dari prestasi belajar, kemampuan berpikir kritis, dan kepercayaan diri siswa
Authors: Azizah Isnaini Nur , Widjajanti Djamilah Bondan 
Published: April 2020

Tujuan penelitian ini untuk mendeskripsikan keefektifan pembelajaran berbasis proyek pada materi statistika ditinjau dari prestasi belajar, kemampuan berpikir kritis, dan kepercayaan diri siswa SMP kelas VII. Pembelajaran berbasis proyek terdiri dari enam langkah yaitu: (1) penentuan proyek; (2) perancangan langkah-langkah penyelesaian proyek; (3) penyusunan jadwal pelaksanaan proyek; (4) penyelesaian proyek dengan fasilitasi dan monitoring guru; (5) penyusunan laporan dan presentasi/publikasi hasil proyek; dan (6) evaluasi dan hasil proyek. Populasi dalam penelitian ini adalah siswa kelas VII SMPN 1 Yogyakarta. Instrumen yang digunakan adalah tes prestasi belajar, tes kemampuan berpikir kritis, angket kepercayaan diri, dan lembar observasi keterlaksanaan pembelajaran. Uji hipotesis menggunakan uji proporsi Z pada taraf signifikan 95% (α = 5%). Berdasarkan hasil uji hipotesis diperoleh proporsi siswa yang prestasi belajarnya telah mencapai KKM lebih dari 75%. Proporsi siswa yang memiliki kemampuan berpikir kritis dan kepercayaan diri pada kategori minimal “baik” lebih dari 75%. Dengan demikian dapat disimpulkan bahwa pembelajaran berbasis proyek efektif ditinjau dari prestasi belajar, kemampuan berpikir kritis, dan kepercayaan diri siswa. The effectiveness of project-based learning viewed from students’ learning achievement, critical thinking skill, and self-confidenceAbstractThe purpose of this study was to describe the effectiveness of project-based learning in statistical material viewed from learning achievement, critical thinking skills, and self-confidence of seventh-grade junior high school students. Project-based learning consists of six steps: (1) determining the project; (2) designing project completion steps; (3) preparing the project implementation schedule; (4) completion of the project with facilitation and monitoring from the teacher; (5) preparation of reports and presentation/ publication of project results; and (6) evaluation and results of the project. The population in this study was seventh-grade students of SMP 1 Yogyakarta, Indonesia. The instruments used were a learning achievement test, a critical thinking ability test, a self-confidence questionnaire, and an observation sheet of learning accomplishments. Hypothesis testing uses the proportion Z test at a significant level of 95% (α = 5%). Based on the results of the hypothesis test, the proportion of students who have learning achievement reached KKM was more than 75%. The proportion of students who have critical thinking skills and self-confidence in the minimum category of "good" was more than 75%. Thus it could be concluded that project-based learning was an effective view from students’ learning achievement, critical thinking skills, and self-confidence.