bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oleophylic Nanospheres Self-Assembly by Emulsion Technique Utilizing the Automatic Nanoscalar Interfacial Alternation (ANIAE)
Authors: Ran Hao , Liu Weibin , Pan Xin , Wu Chuanbin , Quan Guilan , Huang Ying , Cui Yingtong 
Published: June 2020

Background:
The administration of many pharmaceutical active ingredients is often performed
by the injection of an aqueous-based solution. Numerous active ingredients are however, insoluble
in water, which complicates their administration and restricts their efficacy.

Objective:
The current solutions are hindered by both, a time-consuming manufacturing process and
unsuitability for hydrophilic and hydrophobic materials.

Method:
Emulsions of oleophilic active ingredients and polyprotein microspheres are an important
step to overcome insolubility issues.

Results:
Polyprotein microspheres offer a versatile modifiable morphology, thermal responsivity, and
size variation, which allows for the protection and release of assembled biomaterials. In addition, nanospheres
present promising cell phagocytosis outcomes in vivo.

Conclusion:
In this research, a reproducible multifunctional approach, to assemble nanospheres in one
step, using a technique termed “automatic nanoscalar interfacial alternation in emulsion” (ANIAE) was
developed, incorporating a thermally controlled release mechanism for the assembled target active ingredients.
These results demonstrate a viable, universal, multifunctional principal for the pharmaceutical
industry.
Enhance the Quality of Collaborative Filtering Using Tagging
Authors: Banda Latha , Singh Karan 
Published: June 2020

Background:
Due to enormous data on web sites, recommending users for every item
is impossible. For this problem, Recommender Systems (RS) are introduced. RS is categorized into
Content-Based (CB), Collaborative Filtering (CF) and Hybrid RS. Based on these techniques,
recommendations are made to the user. In this, CF is the recent technique used in RS in which
tagging features also provided.

Objective:
Three main issues occur in RS are scalability problem which occurs when there is a
huge data, sparsity problem occurs when rating data is missing and cols start user or item problem
occurs when new user or new item enters in the system. To avoid these issues, here we have proposed
Tag and Time weight model with GA in Collaborative Tagging.

Methods:
Here we have proposed a method Collaborative Tagging (CT) with Tag and Time
weight model with real value genetic algorithm which enhances the recommendation quality by
removing the issues of sparsity and cold start user problems with the help of missing value prediction.
Here in this system, the sparsity problem can be removed using missing value prediction and
cold start problems are removed using tag and time weight model using GA.

Results:
In this study, we have compared the results of Collaborative Filtering with Cosine Similarity
(CF-CS), Collaborative Filtering with Diffusion Similarity (CF-DS), Tag and Time Weight
Model with Diffusion Similarity (TAW-TIW-DS) and Tag and Time Weight Model Using Diffusion
Similarity and Genetic Algorithm (TAW-TIW-DS-GA).

Conclusion:
Here we have compared the proposed approach with the baseline approaches and the
metrics are used MAE, prediction percentage, Hit-rate and Hit-rank. Based on these metrics for
every split, TAW-TIW-DS-GA showed best results as compared to the existing approach.
The Rohingya Crisis: Demand for international pressure for a change in Myanmar
Authors: Ibrahim @ Musa Hariati , Mohd Akahsah Namirah 
Published: June 2020

The notorious violation of the human rights of ethnics in Myanmar has attracted the attention of the international community. Such abuse is threatening the South East Asia peace and security. This article unravels the legal and historical nexus between the Rohingya and Myanmar, supporting their claim for the rights of citizenship. This article suggests a tripartite model of which involves cooperation between the government of Myanmar, ASEAN and, the United Nations. The collective efforts from these three parties are vital to ensure a change in the crisis.
Keywords: ASEAN, Human rights, Rohingya, United Nations.
eISSN: 2398-4287 © 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v5iSI1.2302
NUMBER NEEDED TO TREAT AS A TOOL FOR COST EFFECTIVENESS ANALYSIS: A CASE STUDY IN RENAL TRANSPLANTATION
Authors: GUPTA POOJA , GAMAD NANDA , MOHAN PRAFULL 
Published: June 2020

Objective: To assess the utility of number needed to treat (NNT) as a tool for cost effectiveness analysis.
Methods: Two monoclonal antibodies (MAbs), used for induction therapy viz basiliximab and daclizumab in renal transplantation, were identified. Pivotal placebo controlled clinical trials, mentioned in the innovator package inserts, were compared and analyzed for acute graft rejection and graft survival at 12 mo. NNT viz-a-vis cost was calculated and compared.
Results: Daclizumab was comparable to basiliximab for acute graft rejection (NNT 10 vs. 9) but better for graft survival (20 vs. 25) at 12 mo, when used along with triple drug regimen (cyclosporine, azathioprine and corticosteroid). However, considering the cost of regimen for these drugs, in terms of NNT, basiliximab was more cost effective (INR 12,52,044 vs. 28,70,400 for acute rejection and INR 34,77,900 vs. 57,40,800 for graft survival). On the other hand, when these MAbs were used along with dual drug regimen (cyclosporine and corticosteroid), daclizumab was more cost effective for graft survival at 12 mo. The higher cost of daclizumab regimen (INR 2,87,040 vs. 1,39,116 for basiliximab) was offset by its substantially lower NNT (20 vs. 58-75 for one extra graft survival at 12 mo).
Conclusion: This study demonstrates the utility of NNT in ascertaining relative effectiveness of treatment modalities that would help to formulate appropriate healthcare policies.
Artemisia cina 30 CH homeopathic treatment against Haemonchus contortus
Authors: Higuera-Piedrahita Rosa Isabel , López-Arellano Maria Eugenia , López-Arellano Raquel , Cuenca-Verde César , Cuéllar-Ordaz Jorge Alfredo 
Published: June 2020

The anthelmintic resistance problem is widely recognized in sheep production. Therefore, new methods of control against gastrointestinal nematodes (GIN) need to be integrated. The aim of this work was to assess the toxicity of A. cina 30 CH as a homeopathic product against Haemonchus contortus in in vitro and in vivo assays. A. cina 30 CH was obtained from a commercial laboratory, and confirmation of artemisinin as a key ingredient was performed with mass spectrophotometry. The A. cina 30 CH and the artemisinin pure reagent were used for the inhibition of egg hatching (IEH) and for the inhibition of larval migration of H. contortus L3 (ILM). In addition, three groups of 10 naturally infected lambs with GIN were treated with A. cina 30 CH and albendazole, and 10 were used as control. The parasitic infection was monitored at 0, 7, 14 and 28 d postreatment (PT) to determine the number of eggs per gram (epg) and FAMACHA index. The in vitro data showed 100 % IEH and 64.7 % ILM by A. cina 30 CH, and nonlethal activity was observed with the artemisinin pure reagent. The toxicity of A. cina 30 CH against H. contortus in infected lambs was observed after 7 d of infection. Administration of the A. cina 30 CH yielded a 69 % reduction in the epg at 28 d PT, similar to the albendazole (P<0.05). In conclusion, A. cina 30 CH had the ability to IEH and ILM of H. contortus in in vitro assays and reduced the number of eggs of H. contortus, which is the primary parasitic nematode in grazing lambs, thereby reducing infection.
MASS PRODUCTION OF ENTOMOPATHOGENIC NEMATODES OF LOCAL ISOLATES AS BIOLOGICAL CONTROL AGENTS OF COFFEE BERRY BORER (Hypothenemus hampei Ferr.)
Authors: Wagiyana Wagiyana , Sulistyanto Didik , Waluyo Joko 
Published: June 2020

Entomopathogenic Nematodes (EpNs) that serve as biological control agents include Steinernema spp and Heterorhabditis spp. EPNs Heterorhabditis indicus (Bromo Isolate) has a high toxicity against larvae Lepidoptera and Coleoptera and was successfully developed for mass production in Biological Control Laboratory of Jember University. These nematodes will be formulated as solid and liquid biopesticides. This research aims: to find EPNs local isolates from smallholder coffee plantations; to identify local and in vivo and in vitro cultured EPNs isolates; to determine the pathogenicity of EpNs local isolate against Coffee Berry Borrer (CBB) Hypothenemus hampei Ferr and to formulate EpNs in vitro culture as a liquid and solid formula. These formula were tested for the patogenicity and viability of EpNs to the larvae of H. hampei, Tenebrio molitor and Galleria melonella. The results showed that the pathogenecity of EpNs isolate to the larvae of CBB in Silo was 30% after 24 hours and 90% after 48 hours of in vivo inoculation. However, the mortality of CBB larvae was only 10% by liquid spraying on the coffee berry. The viability was 524 IJ (Infective Juvenile) on liquid formula packed on polyurethane sponge, and this was higher than that on solid formula (330 IJ).
Yerfıstığında Karlılık, Rekabet Edebilirlik Ve Politika Etkileri: Politika Analiz Matrisi
Authors: ÖZALP Burhan , ÖREN Necdet 
Published: June 2020

Amaç: Bu çalışmanın amacı, yerfıstığının karlılık, rekabet edebilirlik durumunu ve yerfıstığında uygulanan tarım politikalarının etkilerini ortaya koymaktır.
Metodoloji: Bu çalışmada yerfıstığının karlılık, rekabet edebilirlik durumunu ve yerfıstığında uygulanan tarım politikalarının etkilerini ortaya koymak için Politika Analiz Matrisi kullanılmıştır.Design/methodology/approach: Bu çalışmada yerfıstığı üretiminin karlılık, rekabet edebilirlik durumunu ve yerfıstığı üretiminde uygulanan tarım politikalarının etkilerini ortaya koymak için Politika Analiz Matrisi kullanılmıştır.Bulgular: PAM sonuçlarına göre, kabuklu yerfıstığı üretiminin 2016 yılı için özel karı 0,28 TL/kg, sosyal karı 2.70 TL/kg olarak bulunmuştur. Kabuklu yerfıstığı üretiminin özel ve sosyal karlılığının pozitif çıkması kabuklu yerfıstığı üretiminin karlı olduğunu ifade etmektedir. PAM kapsamında PAM tablosundan kabuklu yerfıstığı üretimine dair PCR-DRC gibi rekabet edebilirlik ve NPCO-NPCI-EPC gibi politika etkisini gösteren katsayılar hesaplanmıştır. Bütün katsayılar 1’den küçük çıkmıştır. Bu duruma bakarak, yerfıstığı üretiminin karlı ve rekabet edebilir olduğunu ve piyasalarına da ciddi anlamda bir müdahalenin olmadığını ifade etmek mümkündür.Özgünlük/değer: Yerfıstığının karlılık, rekabet edebilirlik durumu ve politika etkileri kantitatif bir şekilde analiz edilerek ortaya konulmuştur.
Signal Analysis of Optical Interference in Relation to Colorimetry for Measurements Made Along Individual Myofibers in Cooked Beef
Authors: Swatland Howard J. 
Published: June 2020

Subsurface reflective interference from A-bands in roast beef persisted under water and some myofibers had interference peaks exceeding the reflectance of white barium sulfate. The number of interference peaks was correlated with CIE (Commission Internationale de lâ€™Ã‰clairage) Y% (r = 0.51, P < 0.001). As the number of peaks increased, the distance from the central white of the CIE chart decreased (r = - 0.52, P < 0.001). Â Myofibers with low scattering had fewer interference peaks (2.9 Â± 0.3, n =10) than myofibers with high scattering (4.9 Â± 1.3, n = 31, P < 0.001).Â Thus, the number of reflecting and interfering layers may be important in relating light scattering along myofibers to surface iridescence. One or a few reflective layers may produce strong interference colors while many layers may produce colorless scattering.Â
Predisposising Factors of Uterine Myoma General Hospital
Authors: Martini Rus , Prasetyorini Tri , Sudiro Karningsih , Hamidah Hamidah , B Yomina 
Published: June 2020

Introduction and Aims : The occurrence of uterine myomas will increase morbidity in women of reproductive age. Uterine myoma is the most common benign tumor in women. This study aims to identify factors related to the occurrence of uterine myoma..Â Method: This research is a descriptive research with cross-sectional design. Data collection is primary data in 2015.Â Results: The study used 74 study subjects, 27 patients who were diagnosed with uterine myoma and 47 patients who were diagnosed with other obstetric diseases. Bivariate analysis showed that there was no relationship between age and parity of patients with the incidence of uterine myoma p = 0.840 and 0.324, there was a significant relationship between the age of menarch and the use of contraception to the incidence of uterine myoma (p = 0.002 [(OR 6.7) 95% Cl2.027 -22.3] and (p = 0.003 [(OR) 8.6 (CI) 95% 2.1-35.2].Â Conclusion: Women who suffer from uterine myoma are > 30 years, with parity > 3 and menarch age < 15 years and using hormonal contraceptives associated with uterine myoma. Suggestion: For health workers can provide information and early screening / early detection on patients, especially on patients who have risk factors.
The Effect of Betel Quid Extract on Wound Healing Process in Male Wistar Rats (Rattus norvegicus L.)
Authors: Puspa Dewi Siti Rusdiana , Fatonah Adelina 
Published: June 2020

Wound can be occured during dental treatment. In outline, there are several phases of wound healing; inflammatory phase, proliferative phase, and maturation phase. Various drugs in various forms are used to accelerate the healing process, but mostly they have side effects. Therefore, traditional medicine, such as betel quid consisted of betel leaf, areca nut, gambier, and calcium hydroxide, is developed. The aim of this study was to investigate the effect of wound healing process in male Wistar rats. A total of 30 male Wistar rats were taken and divided into 5 groups:Â Group 1, 2, and 3 (K1,K2, K3)Â were given 5%, 10% and 15% concentrations of betel quid extract oinments; Group 4 (K4) was positive controlÂ (hyaluronic acid 0.2% oinment); Group 5 (K5) was negative control (placebo oinment). One mm- diameter of lower lip mucosal wounds on rats were created by usingÂ cylinder diamond bur. The oinments were applied twice daily for 10 days. The number of netrophils on first and third day were measured and the thickness of ephitelium on 10 days were determined. All groups ofÂ betel quid extracts exhibited the reduction of the number of neutrophils on inflammatory phase. Group 3 shown as the highest effect and had no significant different with positive control. Betel quid extracts in all groups also improved epithelial thickness on proliferative phase, in which group II and group III had no significant different with positive control. Betel quid extract had effect on wound healing process in male Wistar rats due to its ability in supressing inflamation and in increasing reepithelization.
Organotin (IV) based Rabeprazole and Pregabalin Complexes Formation and Biocidal Investigation
Authors: Tariq Muhammad , Qureshi Ahmad Kaleem , Hamid Muhammad , Abbas Naseem , Hussain Ajaz , Khan Muhammad Naeem 
Published: June 2020

Abstract
New organotin (IV) complexes with NaL1 (sodium salt of 2-[[4-(3-methoxy-propoxy) 3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide) and NaL2 (sodium salt of 3- aminomethyl-5-methylhexanoic acid) were synthesized by the reaction of diorganotin (IV) and triorganotin (IV) salt (Bu3SnCl, Ph3SnCl, Bu2SnCl2, Me2SnCl2) using the solvent (dry toluene) by constant stirring and refluxing. All the organotin (IV) complexes were characterized by different diagnostic techniques such as FT-IR (Infra-red) and UV-visible spectroscopy. The results exhibited that ligand NaL1 (sodium salt) is attached to tin metal by a nitrogen atom of benzimidazole ring and the oxygen atom of the sulfonyl group. While ligand NaL2 (sodium salt) coordinate with tin(IV) moiety through oxygen atom of the carboxylate group. The newly synthesized complexes 1 & 2 of ligand NaL1 (sodium salt) showed trigonal bipyramidal geometry while complexes 3 & 4 octahedral geometry around tin(IV) centre. The organotin(IV) complexes 5-7 of ligand NaL2 (sodium salt) have the tetrahedral geometry around tin(IV) centre. The synthesized complexes (1-7) were tested for antifungal and antibacterial microbial activities. All the complexes showed significant antibacterial and anti-fungal activities against tested bacterial and fungal strains.
Nature Tourism Satisfaction in Okomu National Park, Edo State, Nigeria
Authors: Digun-Aweto Oghenetejri , Fawole Ogbanero Pipy , Van Der Merwe Peet 
Published: June 2020

Abstract

Introduction.
This paper examines the nature tourism satisfaction of tourists visiting Okomu National Park (ONP) in Edo State, Nigeria.

Material and methods.
Questionnaires were randomly administered to tourists visiting the park. Factor analysis was employed to identify the major issues influencing tourist satisfaction when visiting national parks.

Results.
The results indicated that the majority of the tourists were youth and were first-time visitors. Furthermore, the results revealed that management, interpretation, accessibility, and expectation are the major requirements for ensuring a good experience and satisfaction when visiting national parks.

Conclusion. The results of the research reveal that in order to promote tourist satisfaction, managers of national parks need to pay attention to the proper management of the flora and fauna, including the interpretation of natural features.
Lingua Materna, Lingua Receptiva, Lingua Franca, Multilingua Franca? The Linguascape of the Polish-Czech Borderland from the Perspective of Sustainable Multilingualism
Authors: Steciąg Magdalena , Karmowska Anna 
Published: June 2020

Summary
As statistical surveys show, both Poland and the neighbouring Czech Republic are single-ethnic and highly monolingual countries. The observation of the linguistic landscape of the Polish-Czech borderland suggests, however, that the display of common natural heritage is conducive to weakening monolingualism and the development of multilingual practices instead. The hypothesis is being checked in a comparative analysis of the linguistic landscape of two picturesque locations - Czech Adršpach and Polish Karłów where a lot of natural sights in the form of rocks can be found. The case study proves that different languages and communication modes are used to describe these attractions: lingua materna, lingua receptiva, and global or regional lingua franca. The research material includes 211 signs photographed in the Rock City in Adršpach and 283 signs photographed at local tourist attractions near Karłów, namely, on the Szczeliniec Wielki mountain peak and in the Błędne Skały area. The analysis covers both the language hierarchy as well as the specific multilingual character of information signs which refer mainly to the rock objects. The selected photographs are presented in the paper in the attempt to illustrate the particular linguistic practices in examples. The research is based on the assumption of applied ecolinguistics that the diversity of languages should be maintained through appropriate language policy and other activities supporting the preservation of the linguistic and natural heritage. This perspective might shed a new light on the moment of transition from the monolingual paradigm to more open and sustainable multilingual practices in the linguistic landscape of Polish-Czech borderland.
The Forms and Meanings of American Slangs Used inTED 2 Movie Scripts
Authors: Erawanto I Gusti Bagus Kasuto , Parthama I Gusti Ngurah 
Published: June 2020

The title of this paper is “ The Forms and Meanings of American Slang Use in ”TED 2” Movie Script. The aims of this study are to know and describe the forms and types of slang words and phrases used by the characters in TED 2 movie script, and to analyze the meanings of slangs found in TED 2 movie script. The data were collected from the TED 2 movie scripts. The data were collected through internet source. The data was analyzed by descriptive method. The theory used to analyze the problem was proposed by chapman (1998) about the types and forms of slang, while for the meaning of slang the theory used was proposed by Lyons (1981). Theresult of data analysis were presented with descriptive method. The findings of the research found that, there are two kind of slangs in the data, there are primary slang and secondary slang. The total number of data of primary slangs was found are twenty one, while for the secondary slangs they are found nineteen. As to the meaning of slang, there are two kind of meaning found in the data, they are literal meaning and figurative meaning.
Space Design in Batur Sari Villa in Sanur, Bali
Authors: Putra Ida Bagus Gede Kresnayana , Wiryawan I Wayan 
Published: June 2020

Villa is a temporary place, which is located in a distant from crowded area in general villas are built in a place with not many residents and surrounded by beautiful nature to give comfort and serenity. One of the demands is how to maximiz-ing environmental atmosphere into design. Batur Sari villa is located in Sanur, which is identic with the coast. The de-mands is how to create the beach atmosphere in a villa and put into a design. An interior design with nautical concept could be a solution. The aims of interior design is for the development the function and psychological space and with this concept it can gives an environmental atmosphere inside the villa. Nautical concept identic with holyday feels in the beach. Sunshine, waves and sands could become inspirations, with the application of the concept inside the villa, a villa design could fulfill the needs of relax and serenity atmosphere with sorroundings characteristics that’s is needed.
Index Terms— villa, interior design, nautical concept
Study on Application of Design Criteria on the Openstage of Latest Rooms and Displays in Gianyar, Bali
Authors: Krisnha Ida Bagus Gde Wira , Paturusi Syamsul Alam , Bharuna Anak Agung Gde Djaja 
Published: June 2020

The purpose of Open Stage Anyar in Gianyar is to provide a facility or facilitate activities associated with Balinese tradi-tional performing arts, modern performing arts and various types of performances related to the elements of preserva-tion, development of interests and talents to Balinese arts. Criteria of design to help determine the final outcome of a desired design to match the function of the building. Some things in the review of the Criteria of design which includes layout and appearance of the building. the spatial arrangement shows the results of macro and micro-based analysis of the site and and the activities in it. In terms of appearance the building gives an impression or atmosphere that re-flects local knowledge of an area and can also make people become interested when looking at the view of the build-ing.
Index Terms— open stage, arts, performances.
De mãos dadas: ensino e pesquisa na formação docente
Authors: Fernandes Nunes Celia Maria , Tolêdo Corrêa Hércules Tolêdo 
Published: June 2020

Este artigo tem como objetivo apresentar as contribuições de estudos que temos desenvolvido procurando integrar o ensino e a pesquisa junto à formação de professores das séries iniciais do Ensino Fundamental. Nossa metodologia consistiu na coleta de memoriais de leitura e escrita produzidos por alunos do curso de Pedagogia e numa análise de três memoriais escritos por alunos que, além de terem coeficiente de aproveitamento de ensino igual ou superior a nove, interagiram mais com os pesquisadores e apresentaram textos que se destacaram dos demais, tendo em vista suas reflexões e trajetórias. Os resultados mostram três textos com características bem distintas e que nos permitem desvelar as memórias e trajetórias singulares dos pedagogos em formação.