bluuebunny/crossref_metadata_2025_split huggingface dataset:
Discovery and characterization of llama VHH targeting the RO form of human CD45
Authors: Rokkam Deepti , Lupardus Patrick J. 
Published: September 2020

AbstractCD45 is an abundant and highly active cell-surface protein tyrosine phosphatase (PTP) found on cells of hematopoietic origin. CD45 is of particular importance for T-cell function, playing a key role in the activation/inactivation cycle of the T-cell receptor signaling complex. The extracellular domain of CD45 is comprised of an N-terminal mucin-like domain which can be alternatively spliced to a core domain (RO) consisting of four domains with fibronectin 3 domain (FN3)-like topology. The study of CD45 has been hampered by a small set of publicly available antibodies, which we characterized as specific to the N-terminal FN3 domains of CD45 RO. To broaden the human CD45 reagent set, we identified anti-CD45 single domain VHH antibodies from a post-immune llama phage display library. Using a yeast display domain mapping system and affinity measurement we characterized seven unique clonotypes specific for CD45 RO, including binders that target each of the four FN3-like domains. These VHH molecules are important new tools for studying the role of CD45 in T-cell functionin vitroandin vivo.
The limits of institutional work: a field study on auditors' efforts to promote sustainability assurance in a trust society
Authors: Silvola Hanna , Vinnari Eija 
Published: September 2020

PurposeThe purpose of this paper is to enrich extant understanding of the role of both agency and context in the uptake of sustainability assurance. To this end, the authors examine auditors' attempts to promote sustainability assurance and establish it as a practice requiring the professional involvement of auditors.Design/methodology/approachApplying institutional work (Lawrence and Suddaby, 2006) and institutional logics (Thornton, 2002; Thorntonet al., 2012) as the method theories, the authors examine interview data and a variety of documentary evidence collected in Finland, a small society characterized by social and environmental values, beliefs in functioning institutions and public trust in companies behaving responsibly.FindingsWith this study, the authors make two main contributions to extant literature. First, the authors illustrate the limits that society-level logics related to corporate social responsibility, together with the undermining or rejected institutional work of other agents, place especially on the political and cultural work undertaken by auditors. Second, the study responds to Power's (2003) call for country-specific studies by exploring a rather unique context, Finland, where societal trust in companies is arguably stronger than in many other countries and this trust appears to affect how actors perceive the need for sustainability assurance.Originality/valueThis is one of the few accounting studies that combines institutional logics and institutional work to study the uptake of a management fashion, in this case sustainability assurance.
Troubled beginnings: the adverse childhood experiences and placement histories of a detained adolescent population with developmental disorders
Authors: Morris Deborah J. , Webb Elanor Lucy , Parmar Emma , Trundle Grace , McLean Anne 
Published: September 2020

Purpose
People with developmental disorders are significantly more likely to experience adverse childhood experiences (ACEs), although the impact of ACEs on this population is not well understood. Furthermore, considerably less is known about the exposure to, and impact of, ACEs in detained adolescents with complex developmental disorder needs. This paper aims to explore the exposure to ACEs in an adolescent population detained in a secure specialist developmental disorder service.

Design/methodology/approach
A retrospective file review was used to explore ACEs and placement histories within a specialist developmental disorder inpatient service. Data was collated for a convenience sample of 36 adolescents, 9 of whom were female, aged 13–20 years (M = 17.28 years).

Findings
A total of 33 participants (91.7%) had experienced at least 1 ACE, with 58% experiencing 4 or more ACEs and 36% experiencing 6 or more ACEs. The most common ACEs reported were physical abuse (61.6%), parental separation (58.3%) and emotional abuse (55.6%). The majority of participants had also experienced high levels of disruption prior to admission, with an average of four placement breakdowns (range 1–13, standard deviation = 3.1). ACEs held a significant positive association with the total number of placement breakdowns and total number of mental health diagnoses.

Practical implications
Adolescents detained in specialist developmental disorder secure care had, at the point of admission, experienced high levels of adversities and had been exposed to high levels of experienced and observed abuse. The level of exposure to adversity and ongoing disruptions in care suggests that Child and Adolescent Mental Health Services’ developmental secure services should consider adopting dual treatment frameworks of developmental disorder and trauma-informed care.

Originality/value
This study explored the early-life and placement experiences of a marginalised and understudied population.
A bibliometric analysis of recycled concrete research (1978–2019)
Authors: Oshodi Olalekan Shamsideen , Awuzie Bankole Osita , Akotia Julius , Ademiloye Adesola S. , Ngowi Alfred 
Published: September 2020

PurposeThe use of recycled concrete (RC) can reduce the greenhouse emissions associated with the production of cement, which is one of the primary materials used for the execution of construction projects. This research aims to review the state of knowledge in the field of RC research. An understanding of the state of the art in the RC domain justifies future research in this field.Design/methodology/approachA systematic and comprehensive search of RC-related literature was conducted using the Scopus database. In this research, the bibliometrix R-package was used for the analysis of bibliometric information of the selected papers. The software was used to create a map, which highlights the trends and gaps in the RC knowledge domain.FindingsThe results reveal the research themes, clusters, collaboration networks and advancement of knowledge in the field of RC research. The study integrates the literature focussed on RC research and provides a platform for progression of knowledge in this field.Originality/valueThe study contributes to the growing body of knowledge by providing an up-to-date RC knowledge map based on an analysis of bibliographic data. Information gleaned from previous studies suggests that bibliometric review can strengthen and complement the findings emerging from other forms of literature reviews. The study reported here is one of the first studies to provide insights into the evolution of RC research.
Aspirations and environmental performance feedback: a behavioral perspective for green supply chain management
Authors: Shou Yongyi , Shan Shuo , Chen Anlan , Cheng Yang , Boer Harry 
Published: September 2020

PurposeThis study investigates the relationships between environmental performance feedback and green supply chain management (GSCM). It explores how environmental performance above or below aspirations affects the implementation of GSCM practices (specifically sustainable production [SP] and sustainable sourcing [SS]) through the lens of the behavioral theory of the firm (BTOF), which has received scant attention in the operations management literature.Design/methodology/approachThe study used data from the sixth round of the International Manufacturing Strategy Survey (IMSS). It employed hierarchical linear regression to test the proposed hypotheses. Moreover, the study tested an alternate model to rule out the possible role of financial performance aspirations in explaining the implementation of SP and SS.FindingsThe results indicate that organizations determine their efforts put into the two GSCM practices according to environmental performance feedback: the greater the aspiration–environmental performance discrepancy, the stronger the efforts put into implementing GSCM practices.Originality/valueThis study contributes to the GSCM literature by revealing the impact of environmental performance aspirations on the implementation of GSCM practices through the lens of the BTOF. It also extends the BTOF by applying it in the GSCM context and indicating that performance feedback is based on environmental performance instead of financial performance in this specific context.
Smart epidemic tunnel: IoT-based sensor-fusion assistive technology for COVID-19 disinfection
Authors: Pandya Sharnil , Sur Anirban , Kotecha Ketan 
Published: September 2020

Purpose
The purpose of the presented IoT based sensor-fusion assistive technology for COVID-19 disinfection termed as “Smart epidemic tunnel” is to protect an individual using an automatic sanitizer spray system equipped with a sanitizer sensing unit based on individual using an automatic sanitizer spray system equipped with a sanitizer sensing unit based on human motion detection.

Design/methodology/approach
The presented research work discusses a smart epidemic tunnel that can assist an individual in immediate disinfection from COVID-19 infections. The authors have presented a sensor-fusion-based automatic sanitizer tunnel that detects a human using an ultrasonic sensor from the height of 1.5 feet and disinfects him/her using the spread of a sanitizer spray. The presented smart tunnel operates using a solar cell during the day time and switched to a solar power-bank power mode during night timings using a light-dependent register sensing unit.

Findings
The investigation results validate the performance evaluation of the presented smart epidemic tunnel mechanism. The presented smart tunnel can prevent or disinfect an outsider who is entering a particular building or a premise from COVID-19 infection possibilities. Furthermore, it has also been observed that the presented sensor-fusion-based mechanism can disinfect a person in a time of span of just 10 s. The presented smart epidemic tunnel is embedded with an intelligent sanitizer sensing unit which stores the essential information in a cloud platform such as Google Fire-base. Thus, the proposed system favours society by saving time and helps in lowering the spread of coronavirus. It also provides daily, weekly and monthly reports of the counts of individuals, along with in-out timestamps and power usage reports.

Practical implications
The presented system has been designed and developed after the lock-down period to disinfect an individual from the possibility of COVID-19 infections.

Social implications
The presented smart epidemic tunnel reduced the possibility by disinfecting an outside individual/COVID-19 suspect from spreading the COVID-19 infections in a particular building or a premise.

Originality/value
The presented system is an original work done by all the authors which have been installed at the Symbiosis Institute of Technology premise and have undergone rigorous experimentation and testing by the authors and end-users.
Corporate governance mechanisms and corporate performance of firms in Nigeria and Ghana
Authors: Coleman Martha , Wu Mengyun 
Published: September 2020

PurposeThis study investigates the impact of corporate governance (CG) mechanisms with inclusion of compliance and diligence index on corporate performance (CP) of firms in Nigeria and Ghana. It further examines the moderating effect of financial distress on the relationship between CG and CP.Design/methodology/approachThe study used panel data of 102 nonfinancial listed firms of Nigeria and Ghana stock exchange for the period 2012–2016 with total observation of 510. The study first used OLS in estimating the influence of CG mechanisms on CP. Due to multicollinearity in the independent variables, ridge regression was employed.FindingsIt was revealed that ownership structure index and board compliance and diligence index, board size, board disclosure, ownership structure, shareholders' right and board compliance and diligence index had positive influence on ROA and ROE. Growth of Tobin's Q depends on board procedure and board compliance and diligence index. Also, financial distress (ZFS) negatively moderates the relationship between board structure index, board disclosure index, board procedure index, shareholders' right and performance (ROA and ROE) but negatively moderates between ownership structure index and Tobin's Q.Practical implicationsThis study provides interesting findings to policymakers in full implementation of CG codes as stated by OCED (2015) by West African firms with greater emphasis on compliance and diligence index since it positively influences all CP measures.Originality/valueThe study provides evidence of the importance of the introduction of the new index: compliance and diligence, which looks at disclosure of CSR activities. This has been overlooked by most researchers especially in Africa in assessing quality CG mechanisms.
Utilization of Olympic Stadiums: a conceptual stadium legacy framework
Authors: Preuss Holger , Plambeck Anke 
Published: September 2020

PurposeOlympic Stadiums are expensive and large constructions. The media often report on cost overruns based on the extravagant appearance of an Olympic Stadium and the lack of its postgames utilization. The aim of this paper is to provide a conceptual stadium legacy framework consisting of four dimensions and twelve functions that an Olympic Stadium can potentially have.Design/methodology/approachThese were identified by an extensive literature research and an analysis of the findings. Additionally, we collected available data on the specific Olympic Stadiums under review (1984–2016).FindingsThe utilization of Olympic Stadiums varies greatly from city to city. However, 12 functions can be observed as being valid for Olympic Stadiums. The dimensions with its functions are interpreted by the positive/negative values which Olympic Stadiums can have for particular stakeholders. The benefits can be local, regional, national or international. The framework also delivers interconnections of the functions and shows how they interlock and how they can potentially boost the benefits.Practical implicationsFuture bid cities that consider constructing a large stadium can plan their stadium legacy by developing business cases based on the 12 functions developed in this paper. This offers a direct link to marketing, as iconic stadiums and urban development support city marketing.Originality/valueTo date, the complexity of functions and their interconnections, as well as their potential values, have not been examined. Thus, many (media) critiques oversee the benefits an Olympic Stadium can have besides its proper sport utilization.
Estimating and assessing second-order constructs using PLS-PM: the case of composites of composites
Authors: Schuberth Florian , Rademaker Manuel Elias , Henseler Jörg 
Published: September 2020

PurposeThe purpose of this study is threefold: (1) to propose partial least squares path modeling (PLS-PM) as a way to estimate models containing composites of composites and to compare the performance of the PLS-PM approaches in this context, (2) to provide and evaluate two testing procedures to assess the overall fit of such models and (3) to introduce user-friendly step-by-step guidelines.Design/methodology/approachA simulation is conducted to examine the PLS-PM approaches and the performance of the two proposed testing procedures.FindingsThe simulation results show that the two-stage approach, its combination with the repeated indicators approach and the extended repeated indicators approach perform similarly. However, only the former is Fisher consistent. Moreover, the simulation shows that guidelines neglecting model fit assessment miss an important opportunity to detect misspecified models. Finally, the results show that both testing procedures based on the two-stage approach allow for assessment of the model fit.Practical implicationsAnalysts who estimate and assess models containing composites of composites should use the authors’ guidelines, since the majority of existing guidelines neglect model fit assessment and thus omit a crucial step of structural equation modeling.Originality/valueThis study contributes to the understanding of the discussed approaches. Moreover, it highlights the importance of overall model fit assessment and provides insights about testing the fit of models containing composites of composites. Based on these findings, step-by-step guidelines are introduced to estimate and assess models containing composites of composites.
Knowledge, attitudes and practices of sustainability in two university populations, Colombia
Authors: Salas-Zapata Walter , Cardona-Arias Jaiberth Antonio 
Published: September 2020

PurposeThe objective of this study was to analyze knowledge, attitudes and practices (KAP) on the sustainability in two populations of university students.Design/methodology/approachA cross-sectional analytical study with university students.FindingsThe scale employed showed remarkable psychometric properties of reproducibility and validity. Besides, KAP levels were found to be related in the studied population, with higher levels of knowledge and attitudes than those of practice. Knowledge was found to be related to educational cycle and age, attitudes with sex and age and practices with age.Originality/valueThis is one of the few studies in the field of KAP related to sustainability and environmental issues in using a validated psychometric scale. As a consequence, this study also offers methodological details necessary to make comparisons with similar populations in other countries.
Planning for active office intervention in Thailand: survey and in-depth interview of university employees
Authors: Maphong Raweewan , Nakhonket Kasem , Sukonthasab Suchitra 
Published: September 2020

PurposeThis study aimed to explore knowledge, attitude, behavior and causes of sedentary behavior (SB) among office workers and guidelines for active office intervention.Design/methodology/approachThe study was comprised of a survey and an interview. In total, 39 nonacademic office workers responded to the Past-day Adults Sedentary Time-University (PAST-U) and workplace sitting break (SITBRQ) questionnaire to measure SB level, sitting bout, frequency and duration of sitting interrupted in 1 h and in whole working hours. Eleven executives and staffs participated in in-depth interviews to understand knowledge, attitude, behavior and cause of SB and guidelines for active office intervention.FindingsParticipants commonly spend most of their working time in SB (383.85 ± 93.03 min or 6 h 23 min). The interview indicated that at an individual level, participants lack knowledge and understanding of SB. The most common causes of SB are huge workload, personal characteristics and the weather. At the organizational level, there is no policy, no support from colleagues or organizations, while the physical environment is not conducive to reducing SB.Originality/valueThe outcomes of the study are used as basic information and guidelines for establishing an active office intervention in accordance with the culture and context of Thai society. There have been studies in Thailand that examine SB but no studies that have been conducted to study basic information on knowledge, attitudes, behaviors and causes of SB to be used in planning active office intervention to reduce SB.
Open innovation and patenting activity in health care
Authors: Orlando Beatrice , Ballestra Luca Vincenzo , Magni Domitilla , Ciampi Francesco 
Published: September 2020

PurposeThe study aims to explore the interplay between open innovation and intellectual property. Differently from previous studies, we argue that open innovation fosters firm's patenting activity.Design/methodology/approachWe use linear regression analysis to test model's hypotheses. Data are drawn from the Eurostat statistics and refer to a large sample of European firms (NACE Rev.2).FindingsThe findings confirm that open innovation fosters patenting activity in health care, also thanks to huge governments' expenditures in this market.Research limitations/implicationsThe study focuses solely on European firms and it adopts a traditional linear approach. So, we cannot exclude that different dynamics may occur across European borders. Future research should address this concern by focusing on multi-country comparative studies.Practical implicationsOpen innovation is the most suitable model for health industry, because it improves both innovation performance and intellectual capital of firms.Originality/valueThe study tackles an existing gap of the literature by considering how the presence of large customers impacts the strength of intellectual property protection.
Impact of blue economy factors on economic growth in the SAARC countries
Authors: Alharthi Majed , Hanif Imran 
Published: September 2020

Purpose
This study aims to examine the influence of the blue economy factors on the economic growth of the South Asian Association for Regional Cooperation (SAARC) countries.

Design/methodology/approach
Secondary data from 1995 to 2018 have been used for the analysis of eight countries. The contributing factors that measure the fishing production are total aquaculture production, total fisheries production and agriculture, forestry and fishing. Trade and the rate of inflation are used as control variables. Using the feasible generalized least square technique.

Findings
It was found that the blue economy factors play a statistically significant role in the economic growth of SAARC countries and contribute to the achievement of Goal 14 of the United Nations’ sustainable development goals: to conserve and sustainably use the oceans, seas and marine resources for sustainable development.

Originality/value
This study highlights the fact that proper management and utilization of water resources may assist the stimulation of economic growth and meet the challenges of food insecurity by improving the supply of seafood in developing South Asian countries. The study proposes that the sustainable management of water resources requires an alliance across nation states. The alliance will be useful in understanding the concept of the blue economy and the role it plays in ensuring economic growth in developing nations throughout the world.