bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying Change Targets for Posttraumatic Stress Disorder Among Suicidal and Self‐Injuring Women With Borderline Personality Disorder
Authors: Harned Melanie S. , Fitzpatrick Skye , Schmidt Sara C. 
Published: March 2020

AbstractResearch on psychotherapies for posttraumatic stress disorder (PTSD) is increasingly focused on understanding not only which treatments work but why and for whom they work. The present pilot study evaluated the temporal relations between five hypothesized change targets—posttraumatic cognitions, guilt, shame, general emotion dysregulation, and experiential avoidance—and PTSD severity among women with PTSD, borderline personality disorder, and recent suicidal and/or self‐injurious behaviors. Participants (N = 26) were randomized to receive 1 year of dialectical behavior therapy (DBT) with or without the DBT prolonged exposure (DBT PE) protocol for PTSD. Potential change targets and PTSD were assessed at 4‐month intervals during treatment and at 3‐month posttreatment follow‐up. Time‐lagged mixed‐effects models indicated that between‐person differences in all change targets except guilt were associated with more severe PTSD, η2s = .32–.55, and, except for general emotion dysregulation, slowed the rate of change in PTSD severity over time, η2s = .20–.39. In DBT but not in DBT + DBT PE, individuals with higher levels of guilt and experiential avoidance relative to their own average had more severe PTSD at the next assessment point, η2s = .12–.25. The associations between the proposed change targets and PTSD severity were not bidirectional, except for general emotion dysregulation, η2 = .50; and posttraumatic cognitions, η2 = .06. These preliminary findings suggest that trauma‐related cognitions, shame, and guilt, as well as problems regulating them, may be important change targets for improving PTSD in this patient population.
The effects of romantic motives on numerical preferences
Authors: Kim Aekyoung 
Published: March 2020

AbstractThe current research considers whether romantic pair‐bond motivations influence numerical preferences. Across cultures and throughout history, the number “2” has been symbolic of a romantic pair bond. We propose that reminders of romance lead people to prefer the number “2” and other associated even numbers. A series of studies demonstrate that romantic motives—goals related to forming a romantic pair‐bond—increase preference for the number “2” and other numbers of its parity (i.e., even vs. odd numbers) as well as marketing stimuli featuring even (vs. odd) numbers. This effect is specific to romantic motives and does not occur for motives related to other social relationships, such as work relationships, kinship, and friendship. Consistent with the motivational perspective, the desire to form a romantic relationship statistically mediates the effect of romantic cues on preference for even numbers. Subsequently, the effect of romantic motives on preference for even (vs. odd) numbers are suppressed when the focal goal has been already achieved (i.e., having a romantic relationship) or when an individual endorses a promiscuous lifestyle (i.e., having multiple partners simultaneously).
Multi‐institution validation of a new high spatial resolution diode array for SRS and SBRT plan pretreatment quality assurance
Authors: Rose Mark S. , Tirpak Lena , Van Casteren Kristin , Zack Jeff , Simon Tom , Schoenfeld Andreas , Simon William 
Published: March 2020

PurposeThe SRS MapCHECK®, a recently developed patient‐specific quality assurance (PSQA) tool for end‐to‐end testing of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), was evaluated in a multi‐institution study and compared with radiochromic film.MethodsThe SRS MapCHECK was used to collect data on 84 SBRT or SRS PSQA plans/fields at nine institutions on treatment delivery devices (TDD) manufactured by Varian and Elekta. PSQA plans from five different treatment planning software (TPS) were selected and executed on TDDs operating at beam energies of 6 and 10 MV with and without a flattening filter. The patient plans were all VMAT except for ten conformal arc therapy fields. The plans were selected to encompass a range of size and tumor sites including brain, lung, spine, abdomen, ear, pancreas, and liver. Corresponding radiochromic film data was acquired in 50 plans/fields. Results were evaluated using gamma analysis with absolute dose criterion of 3% global dose‐difference (DD) and 1 mm distance‐to‐agreement (DTA).ResultsThe mean 3% DD/1 mm DTA Gamma pass rate of SRS MapCHECK in comparison to film was 95.9%, whereas comparison of SRS MapCHECK to the treatment planning software was 94.7%. 80% of SRS MapCHECK comparisons against film exceed 95% pass rate, and about 30% of SRS MapCHECK comparisons against film exceed 99% pass rate. To maintain good agreement between SRS MapCHECK and film or TPS, authors recommend avoiding plans with a modified modulation complexity score (MMCS) <0.1 arbitrary units (a.u.). In the examples presented, this coincides with avoiding plans with a mu/dose limit of >3 µ/cGy.ConclusionsStereotactic radiosurgery MapCHECK has been validated for PSQA for a variety of clinical SRS/SBRT plans in a wide range of treatment delivery conditions. The SRS MapCHECK comparison with film demonstrates near‐equivalence for analysis of patient‐specific QA deliveries comprised of small field measurements.
Deletion of BAF250a affects oocyte epigenetic modifications and embryonic development
Authors: Zhou Qian , Meng Qing‐Ren , Meng Tie‐Gang , He Qi‐Long , Zhao Zheng‐Hui , Li Qian‐Nan , Lei Wen‐Long , Liu Shu‐Zhen , Schatten Heide , Wang Zhen‐Bo , Sun Qing‐Yuan 
Published: March 2020

AbstractBRG1‐associated factor 250a (BAF250a) is a component of the SWI/SNF adenosine triphosphate‐dependent chromatin remodeling complex, which has been shown to control chromatin structure and transcription. BAF250a was reported to be a key component of the gene regulatory machinery in embryonic stem cells controlling self‐renewal, differentiation, and cell lineage decisions. Here we constructed Baf250aF/F;Gdf9‐cre (Baf250aCKO) mice to specifically delete BAF250a in oocytes to investigate the role of maternal BAF250a in female germ cells and embryo development. Our results showed that BAF250a deletion did not affect folliculogenesis, ovulation, and fertilization, but it caused late embryonic death. RNA sequencing analysis showed that the expression of genes involved in cell proliferation and differentiation, tissue morphogenesis, histone modification, and nucleosome remodeling were perturbed in Baf250aCKO MII oocytes. We showed that covalent histone modifications such as H3K27me3 and H3K27ac were also significantly affected in oocytes, which may reduce oocyte quality and lead to birth defects. In addition, the DNA methylation level of Igf2r, Snrpn, and Peg3 differentially methylated regions was decreased in Baf250aCKO oocytes. Quantitative real‐time polymerase chain reaction analysis showed that the relative messenger RNA (mRNA) expression levels of Igf2r and Snrpn were significantly increased. The mRNA expression level of Dnmt1, Dnmt3a, Dnmt3l, and Uhrf1 was decreased, and the protein expression in these genes was also reduced, which might be the cause for impaired imprinting establishment. In conclusion, our results demonstrate that BAF250a plays an important role in oocyte transcription regulation, epigenetic modifications, and embryo development.
Fish Diversity, Endemism, Threats, and Conservation in the Jinsha River Basin (Upper Yangtze River), China
Authors: Liu Han , Guo Chuanbo , Qu Xiao , Xiong Fangyuan , Paukert Craig P. , Chen Yushun , Su Wei 
Published: March 2020

Abstract
The Jinsha River, which comprises the upper reaches of the Yangtze River, has among the highest freshwater fish biodiversity and endemism in China, but these characteristics have rarely been quantitatively evaluated at the basin scale. We used fish presence–absence data collected from the entire Jinsha River basin (JRB) from 1964 to 2017 to determine patterns in fish biodiversity. In total, 229 freshwater fish species from 9 orders, 26 families, and 110 genera were recorded. Of these species, 161 were endemic to China, with 94 species being endemic to the Yangtze River basin, and 39 species were threatened. Fish species richness was higher in the downstream river reaches and was higher in the main stem than in the tributaries. Overfishing, water pollution, and dam construction have been threatening fish diversity in the JRB for several decades. Conservation strategies similar to those used in North America may be applicable to the JRB to help protect native fishes in this important river basin. Such strategies include (1) assessment of several tributaries as fish reserves; (2) regular adjustment of turbine operations during the fish spawning period; and (3) regulation of the many co-occurring human stressors in the JRB.
Enteral and Parenteral Order Writing Survey—A Collaborative Evaluation Between the Academy of Nutrition and Dietetics’ Dietitians in Nutrition Support Dietetics Practice Group and the American Society for Parenteral and Enteral Nutrition (ASPEN) Dietetics Practice Section
Authors: Peterson Sarah , Dobak Stephanie , Phillips Wendy , Malone Ainsley , Ireton‐Jones Carol , Haney Amanda , Rybicki Mary , Guenter Peggi 
Published: March 2020

AbstractIntroductionIn 2014 and 2017, the Centers for Medicare and Medicaid Services authorized nutrition‐related ordering privileges for registered dietitian nutritionists (RDNs) in hospital and long‐term care settings, respectively. Despite this practice advancement, information describing current parenteral nutrition (PN) and enteral nutrition (EN) ordering practices is lacking. Dietitians in Nutrition Support, a dietetic practice group of the Academy of Nutrition and Dietetics and the Dietetics Practice Section of the American Society of Parenteral and Enteral Nutrition (ASPEN) utilized a survey to describe PN and EN ordering practices among RDNs in the United States.MethodsA cross‐sectional study design was utilized to describe RDN PN and EN ordering privileges. Respondents were asked to describe PN and EN ordering privileges, primary practice setting, primary patient population served, nutrition specialty certification, highest degree earned, career length, and if applicable, the nature of prior denials for ordering privileges or reasons for not applying for ordering privileges.ResultsSeven hundred two RDNs completed the survey (12% response rate), with 664 RDNs providing complete data. The majority of respondents (n = 558) cared for adult/geriatric patients. Among this subset, 47% had no PN ordering privileges; 14% could order and sign PN; 28% could order PN with provider cosignature; 10% could order partial PN with provider cosignature. Nineteen percent of RDNs had no EN ordering privileges; 37% could order and sign EN; 44% could order EN with provider cosignature. RDNs with ordering privileges were more likely to have a nutrition specialty certification and work in an academic or community hospital setting.ConclusionPN and EN ordering privileges are varied because of institution and state requirements. Future research describing the outcomes associated with RDN ordering privileges is needed. This paper has been approved by the Academy's Research, International, and Scientific Affairs team and Council on Research and the ASPEN Board of Directors. This article has been co‐published with permission in the Journal of the Academy of Nutrition and Dietetics. The articles are identical except for minor stylistic and spelling differences in keeping with each journal's style. Either citation can be used when citing this article.
A hybrid modified grey wolf optimization‐sine cosine algorithm‐based power system stabilizer parameter tuning in a multimachine power system
Authors: Devarapalli Ramesh , Bhattacharyya Biplab 
Published: March 2020

SummaryDamping of low‐frequency oscillations due to the unpredictable perturbations of a power network has always been a challenging task. In an interconnected power network, power system stabilizers (PSSs) are in practice to damp out these low‐frequency oscillations by providing a necessary control signal to the automatic voltage regulator unit based on the deviation in generator speed/power output. This article proposes a novel approach of hybrid modified grey wolf optimization‐sine cosine algorithm for tuning the parameters of PSS of an interconnected multimachine power system. The optimal parameter tuning of PSS with the proposed algorithm is achieved by considering a multiobjective function comprises of improving the damping and eigenvalue characteristics of the consolidated multimachine system. A benchmark model of two area four machine system is adopted to investigate the performance achieved with the proposed algorithm in the simultaneous damping of the local and interarea mode of oscillations in a multimachine power system. The system study has been carried out under a self‐clearing fault condition, and the detailed analysis is presented by analyzing the eigenvalues, and their corresponding natural frequencies, damping ratios. The damping nature achieved for the system states under system uncertainties with the proposed algorithm is also presented. The performance obtained from the proposed hybrid algorithm has been compared with the standalone and state‐of‐the‐art optimization methods.
Fabrication of chitosan/collagen/hydroxyapatite scaffolds with encapsulated Cissus quadrangularis extract
Authors: Thongtham Nareerat , Chai‐in Poowadon , Unger Onuma , Boonrungsiman Suwimon , Suwantong Orawan 
Published: March 2020

AbstractHere, we demonstrated the fabrication of a composite scaffold (chitosan [CS], collagen [Col], and hydroxyapatite [HA]) with the incorporation of encapsulated Cissus quadrangularis (CQ) extract for tissue engineering applications. First, the crude extract of CQ loaded nanoparticles were synthesized via double emulsion technique using polycaprolactone (PCL) and polyvinyl alcohol (PVA) as oil and aqueous phases, respectively. Both PCL (20, 40, and 80 mg/mL) and PVA (0.5%, 1%, and 3% w/v) concentrations were varied to determine the optimum concentrations for CQ‐loaded nanoparticle preparation. The CQ‐loaded PCL nanoparticles (CQ‐PCL NPs), prepared with 20 mg/mL PCL and 0.5% (w/v) PVA, exhibited the smallest size of 334.22 ± 43.21 nm with 95.54 ± 1.49% encapsulation efficiency. Then, the CQ‐PCL NPs were incorporated into the CS/Col/HA scaffolds. These scaffolds were also studied for their ultrastructure, pore sizes, chemical composition, compressive modulus, water swelling, weight loss, and biocompatibility. The results showed that the addition of CQ‐PCL NPs into the scaffolds did not dramatically alter the ultrastructure and properties of the scaffolds, compared to CS/Col/HA scaffolds alone. However, incorporation of CQ‐PCL NPs in the scaffolds improved the release profile of CQ by preventing the initial burst release and prolonging the release rate of CQ. In addition, the CQ‐PCL NPs‐loaded CS/Col/HA scaffolds supported the attachment and proliferation of MC3T3‐E1 osteoblast cells.
Detecting kinsenoside from Anoectochilus roxburghii by HPLC‐ELSD with dual columns of NH2 and AQ‐C18
Authors: Wei Mi , Chen Xuemin , Yi Liwen , Yuan Yuanyuan , Zhang Hua , Fu Chunhua , Yu Longjiang 
Published: March 2020

AbstractIntroductionKinsenoside is a characteristic component of Anoectochilus roxburghii and accounts for this herb's medicinal and edible values. No international certified standard method is available for kinsenoside analysis as well as extraction and preservation.ObjectiveTo develop a more accurate analytical method of kinsenoside. The effects of extraction and drying methods of A. roxburghii on kinsenoside efficiency were investigated for the first time, as well as to examine the kinsenoside stability.Material and methodsThe amino (NH2) and AQ‐C18 columns for detecting kinsenoside extract was systematically compared by high‐performance liquid chromatography evaporative light‐scattering detector (HPLC‐ELSD) and HPLC‐diode‐array detector (DAD), respectively. Kinsenoside, its epimer goodyeroside A and the degradation product during preservation were identified through HPLC‐electrospray ionization mass spectrometry (ESI‐MS).ResultsAn accurate method of kinsenoside detection by HPLC‐ELSD with dual columns of NH2 and AQ‐C18 was established. The ratio of Cgoodyeroside A to Ckinsenoside (Y) was determined using the AQ‐C18 column method. The concentration detected by the NH2 column was multiplied by 1/(1 + Y) as the corrected result. Using this novel method, the average deviations were reduced by 7.64%. Moreover, the efficiency of kinsenoside extraction with water was almost twice that of extraction with ethanol. Freeze drying also led to a higher extraction efficiency (38.47% increase) than hot‐air drying did. Furthermore, the degradation of kinsenoside extract exceeded 70% when stored at 37 °C for 3 months.ConclusionThis study provides a reliable experimental method and theoretical basis for the quality control of kinsenoside from A. roxburghii, as well as other glycosides.
Why farmers deviate from recommended pesticide timing: the role of uncertainty and information
Authors: Möhring Niklas , Wuepper David , Musa Tomke , Finger Robert 
Published: March 2020

AbstractBACKGROUNDPrecise timing of pesticide applications, as recommended by decision‐support systems, can ensure crop protection, while maintaining efficient use of pesticides, yet farmers often deviate from recommended timing strategies. Here, we assess and explain farmersʼ choices to follow or not follow recommendations for the timing of fungicide applications against potato late blight in Switzerland.RESULTBased on daily fungicide application records as well as regional application recommendations and disease pressure, we found that 36% of applications took place earlier than recommended. Using regression analysis, we identified the exposure to economic risks of infection, susceptibility of the planted potato varieties to late blight infections, as well as yearly differences in disease occurrence as the most important determinants of farmersʼ application decision.CONCLUSIONOur results indicate that decisions to not follow application recommendations and apply early are linked to available information and uncertainty with respect to disease predictions. Based on our results, we make recommendations on how to account for farmersʼ uncertainty with regard to the timing of pesticide applications in the design of pesticide policies and agricultural decision‐support systems. These include the use of new technologies and data, mandatory reporting and tailor‐made taxes and insurance solutions. Although the focus of this article is on late blight in Switzerland, our analysis can easily be extended to other countries and important plant diseases like powdery mildew in grapevines or Fusarium head blight in winter wheat. © 2020 Society of Chemical Industry
Reframing SU(1,1) Interferometry
Authors: Caves Carlton M. 
Published: March 2020

AbstractSU(1,1) interferometry, proposed in a classic 1986 paper by Yurke, McCall, and Klauder, involves squeezing, displacing, and then unsqueezing two bosonic modes. It has, over the past decade, been implemented in a variety of experiments. Here, SU(1,1) interferometry is taken apart, to see how and why it ticks. SU(1,1) interferometry arises naturally as the two‐mode version of active‐squeezing‐enhanced, back‐action‐evading measurements aimed at detecting the phase‐space displacement of a harmonic oscillator subjected to a classical force. Truncating an SU(1,1) interferometer, by omitting the second two‐mode squeezer, leaves a prototype that uses the entanglement of two‐mode squeezing to detect and characterize a disturbance on one of the two modes from measurement statistics gathered from both modes.
When suppliers shift my boundaries: Supplier employee mobility and its impact on buyer firms' sourcing strategy
Authors: Chondrakis George , Sako Mari 
Published: March 2020

AbstractResearch summaryBuyer firms respond to supplier employee mobility by reshuffling work among suppliers. However, the extant literature has not considered plural‐sourcing firms which can bring work back in‐house. In this paper, we develop a governance framework in which buyers engage in a comparative assessment of the costs associated with different sourcing modes following supplier employee mobility. Due to the imperfect transferability of social capital and associated uncertainty, buyers face increased contracting costs when supplier employees move. This prompts plural‐sourcing buyers to increase their reliance on insourcing when the costs of adjusting in‐house capacity are relatively low and when the costs of switching to alternative suppliers are relatively high. The analysis of data on patent prosecution activities and patent attorney mobility provides support to our theory.Managerial summaryThis study provides a decision framework for buyer firms when their suppliers experience employee departures. Buyers may choose to (a) stay with the suppliers suffering employee losses or (b) follow mobile employees to their new suppliers. However, in both cases contracting becomes more difficult due to the disruption in supplier relationships or the need to work with new suppliers. There is a third option (c) though which is to bring work in‐house. We explain that buyers opt for option (c) when it is easy to expand in‐house capacity and when the costs of switching to alternative suppliers already in use are relatively high. Thus, supplier employee mobility may lead buyer firms to adjust their reliance on outsourcing even when there are no buyer employee departures.
Who violates expectations when? How firms' growth and dividend reputations affect investors' reactions to acquisitions
Authors: Blagoeva Radina R. , Kavusan Korcan , Jansen Justin J. P. 
Published: March 2020

AbstractResearch summaryWe investigate the role of a firm's dividend and growth reputations in shaping investors' interpretations of acquisitions as a negative or positive expectation violation. While our findings reveal that both an acquiring firm's dividend and growth reputations trigger positive investor reactions, they also show that investors react negatively to an acquisition of a target firm with a strong growth reputation when the acquiring firm has a strong dividend reputation. We also find that investors are inclined to give managers “the benefit of the doubt” to the extent that an acquiring firm strategically frames an acquisition announcement in such a way that it provides assurance to investors that the acquisition is meant to exceed investors' expectations about shareholder value creation.Managerial summaryWe study why investors respond to some acquisitions positively and others negatively. We find that the way acquiring and target firms have created shareholder value in the past, and the information conveyed in the acquisition announcements are important determinants of investors' differential reactions to acquisitions. Our findings show that while investors generally react positively to acquisitions by firms known for creating value either through dividends or growth, their reactions become negative when a firm known for value creation through dividends acquires a target known for value creation through growth. We further find that managers can favorably influence investor reactions by making it salient in the acquisition announcement how the acquisition is intended to exceed investors' value creation expectations from the acquiring firm.