bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vivo and in vitro assessment of Trichoderma species and Bacillus thuringiensis integration to mitigate insect pests of brinjal (Solanum melongena L.)
Authors: Nawaz Ahmad , Gogi Muhammad Dildar , Naveed Muhammad , Arshad Muhammad , Sufyan Muhammad , Binyameen Muhammad , Islam Shams Ul , Waseem Muhammad , Ayyub Muhammad Bilal , Arif Muhammad Jalal , Ali Habib 
Published: May 2020

AbstractThe present study was performed to assess the individual and combined potential of 3 different concentrations of Trichoderma sp. (Ts) and Bacillus thuringiensis (Bt) to control brinjal insect pests. Tested formulations were applied on larval and adult stages of the pest. The Trichoderma laboratory bioassays revealed 73% mortality of the aphid species, Aphis gossypii (Glover), and 53% mortality of the cotton leafhopper (Jassids) Amrasca bigutulla bigutulla (Ishida), while opposite results were observed in case of Bt at the highest concentration (1 × 108 cfu ml−1) used. In vivo results revealed that Ts caused a significant population reduction of the aphid (87%) than the jassid (72%), 7 days of post-treatment, at the highest concentration, while non-significant results were observed at the lowest concentrations. A. gossypii was significantly found more susceptible to the mixture of Trichoderma + Bt than the jassid (62%) and brinjal shoot and fruit borer (65%) even after 48 h of treatment application. The combined application (Trichoderma + Bt) showed maximum population reduction of jassid (88%), aphid (95%), and BSFB (96%), respectively, 7 days post-applications. The positive correlation among time and concentration was observed. The result may imply that consortium of these microbial organisms could be effective and can be incorporated in IPM programs for effective control of sucking and chewing insect pests of brinjal.
The Table of the Dead at the celebration of the deceased in the Ecuadorian Coastal Lowlands region
Authors: Silva Gómez Efrén , Quezada Tobar David , Orden Mejía Miguel , Quezada Tobar Estefanía 
Published: May 2020

AbstractEcuador is considered a multi-ethnic and multicultural country. It has several celebrations that are part of its traditions. One of these celebrations is the feast of All Souls Day, commemorated in a different way in the four regions of the country. In the coastal lowlands region, especially in the province of Santa Elena, the Tugaduaja community performs a ritual called theTable of the Dead, which consists of displaying various foods that the deceased relatives loved. The objective of this article is to describe the elaboration of this ritual from the ethnographic point of view, for which in-depth interviews and observation cards were used. TheTable of the Deadis held 2 days a year, on one occasion for dead children and on the other for dead adults. The festive meals that can never be absent from the table are roasted sweet potato, dead man’s bread, corn custard, and goat stew. This social, ritual and festive use contributes to the dialog and respect between the different cultures and communities of Ecuador.
Computer-aided analysis in evaluation and grading of interstitial lung diseases in correlation with CT-based visual scoring and pulmonary function tests
Authors: Higazi Mahmoud M. , Abdelgawad Ehab Ali , Kaseem Ahmed H. , Adly Kerria Raif 
Published: May 2020

Abstract
Background
Interstitial lung diseases (ILDs) represent a large group of more than 200 different entities. High resolution computed tomography (HRCT) is accepted as the gold standard imaging modality in the diagnosis of ILD. The visual-based scoring offers an advantage in finding a specific type of ILD. Computer-aided CT attenuation histogram is another way of characterizing and quantifying diffuse lung disease. The histogram analysis (HIST) consists of calculating skewness, kurtosis, and mean lung density to quantify lung disease and monitor progression. The aim of our study was to investigate the value of computer-aided analysis of HRCT for interstitial lung diseases in correlation with scoring and pulmonary function tests.

Results
This prospective study included 50 patients with suspected ILD. The mean age of patients was 46.7 years ± 12.5. Mean forced expiratory volume FEV1 was 63.6 ± 20.9. HRCT examination was done for all patients followed by CT-based visual scaling. Most of the studied patients (43.3%) had a CT visual semi-quantitative scoring ranged between 40 and 64. CT-based lung density histograms (LDH) were obtained for all patients using the 3D Slicer Software (Chest Imaging Platform). There was a significant difference between patient’s groups of different (mild, moderate, and severe) grades of ILD according to FEV1 regarding MLD, skewness, and kurtosis of corresponding CT-based density histograms (p values < 0.001). More significant and higher correlation was observed between computerized aided CT quantified mean lung densities (MLD) and (FEV1) (p value < 0.001 and r = − 0.570). The ROC curve analysis demonstrated good performance for CT visual scoring with PFT (AUC = 0.71); a cutoff scoring 15 or higher was associated with best sensitivity (75%) and specificity (100%). Meanwhile, ROC curve analysis for MLD and FEV1 demonstrated an excellent performance for computer-based CT quantification (AUC = 0.85) with a value of − 769 HU which increased sensitivity to 65% and specificity to 100%.

Conclusion
Visual-based scoring techniques offer an advantage in finding a specific type of ILD. Computer-based quantification system could be a means for accurately monitoring the disease progression or response to therapy.
Factors Associated With Chemotherapy-Induced Vomiting Control in Pediatric Patients Receiving Moderately or Highly Emetogenic Chemotherapy: A Pooled Analysis
Authors: Dupuis L. Lee , Tomlinson George A. , Pong Annpey , Sung Lillian , Bickham Kara 
Published: May 2020

PURPOSE To identify factors associated with chemotherapy-induced vomiting (CIV) control in pediatric patients receiving highly emetogenic chemotherapy (HEC) or moderately emetogenic chemotherapy (MEC). MATERIALS AND METHODS An individual, patient‐level, pooled analysis was performed using data from five clinical trials of aprepitant or fosaprepitant in pediatric patients receiving HEC or MEC. The proportion of individuals who experienced no vomiting (complete CIV control) during the phase of interest was the primary study end point. The association of acute-phase complete CIV control (from first chemotherapy dose to 24 hours after the last chemotherapy dose of the chemotherapy block) with age, sex, race, cancer type, acute-phase duration, and antiemetic regimen was examined. Association of the same factors and acute-phase complete CIV control with complete CIV control in the delayed phase (end of acute phase until ≤ 96 hours later) was examined. RESULTS A total of 735 patients (mean age, 8.9 years; range, 0.3 to 17.9 years) were included in the acute-phase analysis. Acute-phase complete CIV control was less likely in older patients (relative risk [RR], 0.97 per year; 95% CI, 0.96 to 0.98 per year) and longer acute-phase duration (RR, 0.89 per day; 95% CI, 0.84 to 0.94 per day). Receipt of ondansetron plus aprepitant or fosaprepitant was associated with a higher likelihood of acute-phase complete CIV control versus ondansetron alone (RR, 1.28; 95% CI, 1.09 to 1.50). Delayed-phase complete CIV control was more likely in patients with acute-phase complete CIV control (RR, 1.19; 95% CI, 1.06 to 1.34) and in those who received aprepitant or fosaprepitant. CONCLUSION Younger age, shorter acute-phase duration, and antiemetic regimen were associated with acute-phase complete CIV control in pediatric patients receiving HEC or MEC. Acute-phase complete CIV control and antiemetic regimen were associated with delayed-phase complete CIV control.
A Drosophila model to study retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8
Authors: Stanković Dimitrije , Claudius Ann-Katrin , Schertel Thomas , Bresser Tina , Uhlirova Mirka 
Published: May 2020

ABSTRACT
Retinitis pigmentosa (RP) represents genetically heterogeneous and clinically variable disease characterized by progressive degeneration of photoreceptors resulting in a gradual loss of vision. The autosomal dominant RP type 13 (RP13) has been linked to the malfunction of PRPF8, an essential component of the spliceosome. Over 20 different RP-associated PRPF8 mutations have been identified in human patients. However, the cellular and molecular consequences of their expression in vivo in specific tissue contexts remain largely unknown. Here, we establish a Drosophila melanogaster model for RP13 by introducing the nine distinct RP mutations into the fly PRPF8 ortholog prp8 and express the mutant proteins in precise spatiotemporal patterns using the Gal4/UAS system. We show that all nine RP-Prp8 mutant proteins negatively impact developmental timing, albeit to a different extent, when expressed in the endocrine cells producing the primary insect moulting hormone. In the developing eye primordium, uncommitted epithelial precursors rather than differentiated photoreceptors appeared sensitive to Prp8 malfunction. Expression of the two most pathogenic variants, Prp8S&gt;F and Prp8H&gt;R, induced apoptosis causing alterations to the adult eye morphology. The affected tissue mounted stress and cytoprotective responses, while genetic programs underlying neuronal function were attenuated. Importantly, the penetrance and expressivity increased under prp8 heterozygosity. In contrast, blocking apoptosis alleviated cell loss but not the redox imbalance. Remarkably, the pathogenicity of the RP-Prp8 mutations in Drosophila correlates with the severity of clinical phenotypes in patients carrying the equivalent mutations, highlighting the suitability of the Drosophila model for in-depth functional studies of the mechanisms underlying RP13 etiology.
This article has an associated First Person interview with the first author of the paper.
Current status of global research on novel coronavirus disease (COVID-19): a bibliometric analysis and knowledge mapping
Authors: Hossain Md Mahbub 
Published: May 2020

Background: Novel coronavirus disease (COVID-19) is a major global health concern due to its pathogenicity and widespread distribution around the world. Despite a growing interest, little is known about the current state of research on COVID-19. This bibliometric study evaluated the contemporary scientific literature to assess the evolution of knowledge on COVID-19, identify the leading research stakeholders, and analyze the conceptual areas of knowledge development in this domain. Methods: Bibliometric data on COVID-19 related studies published until April 1, 2020, were retrieved from Web of Science core collection. Further, a quantitative evaluation and visualizations of knowledge areas in COVID-19 research were created by statistical and text-mining approaches using bibliometric tools and R software. Results: A total of 422 citations were retained in this study, including journal articles, reviews, letters, and other publications. The mean number of authors and citations per document was 3.91 and 2.47, respectively. Also, the top ten articles, authors, and journals were identified based on the frequencies of citations and publications. Networks of contributing authors, institutions, and countries were visualized in maps, which highlight discrete developments in research collaborations. Major areas identified through evaluating keywords and text data included genetic, epidemiological, zoonotic, and other biological topics associated with COVID-19. Conclusions: Current status of COVID-19 research shows early development in different areas of knowledge. More research should be conducted in less-explored areas, including socioeconomic determinants and impacts of COVID-19. Also, global research collaboration should be encouraged for strengthening evidence-based decision-making preventing and addressing the COVID-19 pandemic and aftermath.
Recent advances in the technology of anesthesia
Authors: Seger Christian , Cannesson Maxime 
Published: May 2020

The practice of anesthesiology is inextricably dependent upon technology. Anesthetics were first made possible, then increasingly safe, and now more scalable and efficient in part due to advances in monitoring and delivery technology. Herein, we discuss salient advances of the last three years in the technology of anesthesiology. Consumer technology and telemedicine have exploded onto the scene of outpatient medicine, and perioperative management is no exception. Preoperative evaluations have been done via teleconference, and copious consumer-generated health data is available. Regulators have acknowledged the vast potential found in the transfer of consumer technology to medical practice, but issues of privacy, data ownership/security, and validity remain. Inside the operating suite, monitoring has become less invasive, and clinical decision support systems are common. These technologies are susceptible to the “garbage in, garbage out” conundrum plaguing artificial intelligence, but they will improve as network latency decreases. Automation looms large in the future of anesthesiology as closed-loop anesthesia delivery systems are being tested in combination (moving toward a comprehensive system). Moving forward, consumer health companies will search for applications of their technology, and loosely regulated health markets will see earlier adoption of next-generation technology. Innovations coming to anesthesia will need to account for human factors as the anesthesia provider is increasingly considered a component of the patient care apparatus.
Compressed single-shot hyperspectral imaging for combustion diagnostics
Authors: He Zichen , Williamson Nathan , Smith Cary D. , Gragston Mark , Zhang Zhili 
Published: May 2020

This paper demonstrates a compressed sensing-based single-shot hyperspectral imaging system for combustion diagnostics. The hyperspectral system can capture well-resolved spectra in a 2D plane through a single shot, i.e., converting a 3D data cube of 2D spatial and 1D spectral information into a compressed 2D hyperspectral image. Experimentally, the light emissions are first coded by a random binary pattern to generate the hyperspectral content, which is then sent through a spectrometer. The resulting compressed hyperspectral image is computationally analyzed to recover original 2D spatial and 1D spectral information.

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chemiluminescence emissions of a methane/air flame at various equivalence ratios are measured using the compressed hyperspectral imaging technique. Comparison to traditional measurements shows good agreement in the correlation of emission ratio to equivalence ratio. The technique can be further applied to other laser-based combustion diagnostics.
IJEN CAR FREE DAY: Gelanggang Olahraga Imajiner di Kota Malang
Authors: Harjo Indhar Wahyu Wira 
Published: May 2020

The availability of sports facilities and the number of residents in Malang shows a lack of balance in proportion. The government of Malang city has made some attempts to collaborate with any parties to allocate the proportional sports facilities for the residents. To deal with the problem, the government has designed a program called Ijen Car Free Day (ICFD) as one alternative of solutions. The Ijen Street, which mostly functions as the main street, has also served as a sport center. The present study aims at investigating the utilization of roads of Ijen Street as one of sports centers. The analysis is carried out to re-observe the use of public space that has experienced some transformations. The data collected are examined thoroughly by implementing the research method of descriptive qualitative. The result of the study indicates that the Ijen Street is a sterile road section of motor vehicles at 06:00 up to 10:00, and during the time, the road is used for some sports activities. The so-called elite region of Malang city has transformed into courts for morning gymnastics and jogging tracks along the way. In addition, the area is also used as a social, economic, and cultural spaces. The visitors of Ijen CFD often takes the chance to sell some products, join some communities, and perform some shows of art and culture. The comprehension of the models of space use is necessary to optimize the management of Ijen CFD in the future. Proporsi ketersediaan fasilitas olahraga dengan jumlah penduduk di Kota Malang memperlihatkan ketimpangan. Pemerintah Kota Malang berupaya melakukan kerja sama dengan berbagai pihak untuk menyediakan fasilitas olahraga yang proporsional bagi warga. Untuk mengatasi permasalahan tersebut, Pemerintah Kota Malang merancang Program Ijen Car Free Day (ICFD) sebagai alternatif solusi dengan mengalihfungsikan Jalan Besar Ijen sebagai wahana olahraga. Penelitian ini menelaah penggunaan ruas Jalan Besar Ijen sebagai gelanggang olahraga. Telaah tersebut untuk meninjau kembali penggunaan ruang publik yang mengalami transformasi pemanfaatan. Data diulas menggunakan metode penelitian kualitatif deskriptif. Hasil penelitian menunjukkan bahwa kawasan Jalan Ijen menjadi ruas jalan yang steril dari kendaraan bermotor sejak pukul 06.00 hingga 10.00. Di rentang waktu itu, jalan raya dimanfaatkan untuk ruang olahraga. Sepanjang kawasan itu berubah menjadi ‘lapangan’ untuk senam pagi, joging track, atau jalan santai. Selain itu, kawasan tersebut juga digunakan sebagai ruang sosial, ekonomi dan budaya. Para pengunjung ICFD acapkali menggunakan kesempatan itu untuk berjualan, berkumpul dengan komunitas, dan melakukan pertunjukan seni-budaya. Pemahaman terhadap model-model penggunaan ruang tersebut diperlukan untuk mengoptimalkan pengelolaan Ijen CFD.
Note sur la réception du
Testament d’Abraham
dans la tradition arabo-islamique
Authors: Croq Alice 
Published: May 2020

Abstract
This brief note aims at contributing to the study of the reception of parabiblical narratives in hadith literature and Islamic historiography. Taking the Testament of Abraham as a case study, it sets out to analyse a particular literary motif shared by this text and an early version of the miʿrāǧ (Ascension) of the Prophet Muhammad. The comparative analysis demonstrates that the Testament of Abraham could have provided a number of elements for the redaction of at least one particular section of the miʿrāǧ. This hypothesis finds support in other cases of textual correspondence between several sections of the Testament of Abraham and other Islamic works such as the Tafsīr of Muqātil ibn Sulaymān (d. 150/767), the unedited Kitāb Mubtadaʾ al-dunyā wa-qiṣaṣ al-anbiyāʾ of Abū Ḥuḏayfa al-Buḫārī Isḥāq ibn Bišr (d. 206/821) and Ibn ʿAsākir’s Taʾrīḫ madīnat Dimašq (d. 571/1176). The examined material thus throws additional light on the continuity between late antique apocrypha and nascent Arabic literature.
Inflammation Induced by Natural Neuronal Death and LPS Regulates Neural Progenitor Cell Proliferation in the Healthy Adult Brain
Authors: Larson Tracy A. , Tokareva Yekaterina , Cole Marianne Meritt , Brenowitz Eliot A. 
Published: May 2020

AbstractInflammation is typically considered a negative response to injury or insult; however, recent advances demonstrate that inflammatory cells regulate development, plasticity, and homeostasis through anticytotoxic, progenerative responses. Here, we extend analyses of neuroinflammation to natural neurodegenerative and homeostatic states by exploiting seasonal plasticity in cytoarchitecture of the avian telencephalic song control nucleus, high vocal center [HVC (proper name)], in the songbird Gambel’s white-crowned sparrow (Zonotrichia leucophrys gambelii). We report that local injection of the endotoxin lipopolysaccharide into HVC of birds in both breeding (high circulating testosterone level) and nonbreeding (low circulating testosterone level) conditions increased neural progenitor cell proliferation in the nearby but distinct ventricular zone. Additionally, we found that oral administration of the anti-inflammatory drug minocycline during seasonal regression of HVC reduced microglia activation in HVC and prevented the normal proliferative response in the ventricular zone to apoptosis in HVC. Our results suggest that local neuroinflammation positively regulates neural progenitor cell proliferation and, in turn, contributes to the previously described repatterning of HVC cytoarchitecture following seasonally induced neuronal loss.
Human Face-Selective Cortex Does Not Distinguish between Members of a Racial Outgroup
Authors: Reggev Niv , Brodie Kirstan , Cikara Mina , Mitchell Jason P. 
Published: May 2020

AbstractPeople often fail to individuate members of social outgroups, a phenomenon known as the outgroup homogeneity effect. Here, we used functional magnetic resonance imaging (fMRI) repetition suppression to investigate the neural representation underlying this effect. In a preregistered study, White human perceivers (N = 29) responded to pairs of faces depicting White or Black targets. In each pair, the second face depicted either the same target as the first face, a different target from the same race, or a scrambled face outline. We localized face-selective neural regions via an independent task, and demonstrated that neural activity in the fusiform face area (FFA) distinguished different faces only when targets belonged to the perceivers’ racial ingroup (White). By contrast, face-selective cortex did not discriminate between other-race individuals. Moreover, across two studies (totalN = 67) perceivers were slower to discriminate between different outgroup members and remembered them to a lesser extent. Together, these results suggest that the outgroup homogeneity effect arises when early-to-mid-level visual processing results in an erroneous overlap of representations of outgroup members.
Predicting Neural Response Latency of the Human Early Visual Cortex from MRI-Based Tissue Measurements of the Optic Radiation
Authors: Takemura Hiromasa , Yuasa Kenichi , Amano Kaoru 
Published: May 2020

AbstractAlthough the non-invasive measurement of visually evoked responses has been extensively studied, the structural basis of variabilities in latency in healthy humans is not well understood. We investigated how tissue properties of optic radiation could predict interindividual variability in the latency of the initial visually evoked component (C1), which may originate from the primary visual cortex (V1). We collected C1 peak latency data using magnetoencephalography (MEG) and checkerboard stimuli, and multiple structural magnetic resonance imaging (MRI) data from 20 healthy subjects. While we varied the contrast and position of the stimuli, the C1 measurement was most reliable when high-contrast stimuli were presented to the lower visual field (LVF). We then attempted to predict interindividual variability in C1 peak latency in this stimulus condition with a multiple regression model using MRI parameters along the optic radiation. We found that this model could predict >20% of variance in C1 latency, when the data were averaged across the hemispheres. The model using the corticospinal tract did not predict variability in C1 latency, suggesting that there is no evidence for generalization to a non-visual tract. In conclusion, our results suggest that the variability in neural latencies in the early visual cortex in healthy subjects can be partly explained by tissue properties along the optic radiation. We discuss the challenges of predicting neural latency using current structural neuroimaging methods and other factors that may explain interindividual variance in neural latency.