bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer
Authors: Škapik Ivana Paskov , Giacomelli Chiara , Hahn Sarah , Deinlein Hanna , Gallant Peter , Diebold Mathias , Biayna Josep , Hendricks Anne , Olimski Leon , Otto Christoph , Kastner Carolin , Wolf Elmar , Schülein-Völk Christina , Maurus Katja , Rosenwald Andreas , Schleussner Nikolai , Jackstadt Rene-Filip , Schlegel Nicolas , Germer Christoph-Thomas , Bushell Martin , Eilers Martin , Schmidt Stefanie , Wiegering Armin 
Published: February 2025

Abstract
Protein synthesis is an essential process, deregulated in multiple tumor types showing differential dependence on translation factors compared to untransformed tissue. We show that colorectal cancer (CRC) with loss-of-function mutation in the APC tumor suppressor depends on an oncogenic translation program regulated by the ability to sense phosphorylated eIF2α (p-eIF2α). Despite increased protein synthesis rates following APC loss, eIF2α phosphorylation, typically associated with translation inhibition, is enhanced in CRC. Elevated p-eIF2α, and its proper sensing by the decameric eIF2B complex, are essential to balance translation. Knockdown or mutation of eIF2Bα and eIF2Bδ, two eIF2B subunits responsible for sensing p-eIF2α, impairs CRC viability, demonstrating that the eIF2B/p-eIF2α nexus is vital for CRC. Specifically, the decameric eIF2B linked by two eIF2Bα subunits is critical for translating growth-promoting mRNAs which are induced upon APC loss. Depletion of eIF2Bα in APC-deficient murine and patient-derived organoids establishes a therapeutic window, validating eIF2Bα as a target for clinical intervention. In conclusion, we demonstrate how the expression of the oncogenic signature in CRC is crucially controlled at the translational level.
Drosophila Alms1 proteins regulate centriolar cartwheel assembly by enabling Plk4-Ana2 amplification loop
Authors: Brunet Marine , Thomas Joëlle , Lapart Jean-André , Krüttli Léo , Laporte Marine H , Riparbelli Maria Giovanna , Callaini Giuliano , Durand Bénédicte , Morel Véronique 
Published: February 2025

Abstract
Centrioles play a central role in cell division by recruiting pericentriolar material (PCM) to form the centrosome. Alterations in centriole number or function lead to various diseases including cancer or microcephaly. Centriole duplication is a highly conserved mechanism in eukaryotes. Here, we show that the two Drosophila orthologs of the Alström syndrome protein 1 (Alms1a and Alms1b) are unexpected novel players of centriole duplication in fly. Using Ultrastructure Expansion Microscopy, we reveal that Alms1a is a PCM protein that is loaded proximally on centrioles at the onset of procentriole formation, whereas Alms1b caps the base of mature centrioles. We demonstrate that chronic loss of Alms1 proteins (with RNA null alleles) affects PCM maturation, whereas their acute loss (in RNAi KD) completely disrupts procentriole formation before Sas-6 cartwheel assembly. We establish that Alms1 proteins are required for the amplification of the Plk4-Ana2 pool at the duplication site and the subsequent Sas-6 recruitment. Thus, Alms1 proteins are novel critical but highly buffered regulators of PCM and cartwheel assembly in flies.
Structure of the MUC5AC VWD3 assembly responsible for the formation of net-like mucin polymers
Authors: Trillo-Muyo Sergio , Ermund Anna , Hansson Gunnar C 
Published: February 2025

Abstract
Gel-forming mucins MUC5AC and MUC5B constitute the main structural component of the mucus in the respiratory system. Secreted mucins interact specifically with each other and other molecules giving mucus specific properties. We determined the cryoEM structures of the wild type D3 assembly of the human MUC5AC mucin and the structural single nucleotide polymorphisms (SNP) variants Arg996Gln and Arg1201Trp that affect intermolecular interactions. Our structures explain the MUC5AC N-terminal non-covalent oligomerization after secretion. The D3 assembly forms covalent dimers that can appear in two alternative conformations, open and closed, where the closed conformation dimers interact through an arginine-rich loop in the TIL3 domain to form tetramers. Our study provides a model to explain MUC5AC net-like structures and how the two SNPs will affect mucus organization, something that might affect lung and other diseases.
‘Wanting of hir wille’: Arendtian sovereignty and plurality in The Knight’s Tale
Authors: Cibula Peter 
Published: February 2025

Abstract

The Knight’s Tale presents patriarchal sovereignty in the figure of Theseus, who exercises his power through the capacities of homo faber (man the tool user and craftsman). This fashioned political realm is seductive; however, Hannah Arendt argues that the transformation of the political realm through homo faber’s work creates an anti-politics that survives through a Stoic illusion of freedom. Arendt’s work allows us to recognize why Theseus’s use of the capacities of homo faber to master Arcite and Palamon never truly arrives at its intent since it thrives through the suppression of what Arendt denotes as the human political condition: plurality. I argue that reading Emelye’s prayer and the negotiation of Chaucer’s gods through Arendt allows us to understand how sovereignty is a weaker exercise of man’s capacities than speech and action which, following Arendt, operate within the non-sovereign reality of human life.
When seeing is not believing: self-efficacy and cynicism in the era of intelligent media
Authors: Liu Qiang , Wang Lin , Luo Mengyu 
Published: February 2025

Abstract
The rise of deep synthesis technology has garnered significant attention with the advancement of artificial intelligence (AI). Social media platforms are increasingly populated with news content featuring AI-generated images. When browsing fragmented online information, it remains uncertain whether users pay attention to the source of this content. This study examines AI self-efficacy and user cynicism, exploring users’ cognitive and perceptual attitudes, as well as their behavioural tendencies toward news images generated by deepfake technology. The results of two experiments (N = 1826) suggest that when AI self-efficacy is lowered, users display greater cynicism toward the authenticity of news. Furthermore, differences in information processing strategies were observed depending on the content features of the news. Specifically, users with reduced AI self-efficacy were more likely to express cynicism toward high-relevance news compared to low-relevance news. Similarly, they were more likely to question the authenticity of low-risk news compared to high-risk news.
Simple, highly stable transfer cavity for laser stabilization based on a carbon-fiber reinforced polymer spacer
Authors: Zwettler T. , Xue Z. , Bolognini G. , Bühler T. , Hruby L. , Fabre A. , Donner T. , Brantut J.-P. 
Published: February 2025

We describe the design and operation of a high-stability Fabry–Pérot cavity, for laser stabilization in cavity quantum-electrodynamics experiments. Our design is based on an inexpensive and readily available uniaxial carbon-fiber reinforced polymer tube spacer, featuring an ultra-low thermal expansion coefficient. As a result, our 136 mm-long cavity, which has a finesse of 5160, shows a coefficient of thermal expansion of 1.6 × 10−6 K−1. Enclosing it in a hermetic chamber at room-pressure and using simple temperature stabilization, we observe absolute frequency excursions over a full day below 50 MHz for a laser operating at 446.785 THz. The frequency stability is limited by the imperfect thermal isolation from the environment and can be corrected using a built-in piezoelectric actuator. In addition, we discuss a different variant of this design and identify future improvements. Our system provides a cost-effective and robust solution for transferring laser stability over different wavelengths, as well as for linewidth reduction or spectral filtering of CW laser sources for applications in quantum science.
A long-lifetime and maintenance-free atomic cell for laser spectroscopy experiment of 6Li atoms
Authors: Song Hong-Fang , Wu Jie , Li Ke , Wang Fu-Qiang 
Published: February 2025

We report a hot pipe for a laser spectroscopy experiment of lithium atoms, which can work at a relatively low temperature of ∼280 °C for observing a nearly lifetime-limited laser spectrum of D2 line transitions of 6Li atoms. The spectrum has a high signal-to-noise ratio and serves as a stable reference for laser frequency stabilization. The main structure of the pipe includes an 80-cm-long stainless steel tube with a 19.05 mm inner diameter and several standard vacuum components, leading to an overall axial length of ∼1.1 m. Instead of filling noble atomic gas to protect the viewports from contamination, we find that the residual gas around both windows can act as buffer gas, and almost no contamination is discernible after over four years of operation. Furthermore, the pipe exhibits characteristics of free maintenance and simple operation, as no vacuum pumping process is needed after preparation. Even when being idle in a cold state for months, the vacuum can be recovered by heating the pipe to a higher temperature above the melting point (∼181 °C) of bulk lithium for a day.
Status and prospect of weak radiative hyperon decays
Authors: Shi Rui-Xiang , Jia Zekun , Geng Li-Sheng , Peng Haiping , Zhao Qiang , Zhou Xiaorong 
Published: February 2025

Abstract
Weak radiative hyperon decays represent a rich interplay between weak interactions and the internal structure of baryons, offering profound insights into Quantum Chromodynamics and weak interactions. Recent experimental observations, particularly from BESIII, have revealed deviations from theoretical predictions. These deviations could signal new physics or the need for refined theoretical models incorporating intermediate resonance effects. This review discusses recent theoretical advancements and key experimental findings, focusing on recent measurements from BESIII and their implications for strong interactions and baryon structure.
Cherenkov Telescope Array Observatory sensitivity to heavy Galactic Cosmic Rays and the shape of particle spectrum
Authors: Dubos C. , Sharma P. , Patel S. , Suomijärvi T. 
Published: February 2025

Abstract
The origin of Galactic Cosmic Rays (GCRs) and the potential role of Supernova Remnants (SNRs) as cosmic-ray (CR) accelerators remain subjects of ongoing debate. To shed more light on this topic, we have studied the spectral shapes of two SNRs, RX J1713.7-3946 and HAWC J2227+610, performing simulations for the Cherenkov Telescope Array Observatory (CTAO).
The previous multi-wavelength (MWL) analysis on these two sources showed an important hadronic contribution at high energies. The interaction of the GCRs accelerated by the SNRs with the medium around the accelerator leads to a process of pion decay (PD) that produces gamma-rays (γ-rays). These emissions, detectable by CTAO, offer an indirect means of pinpointing the CR source.

Two scenarios have been considered: the contribution of heavy CRs and different cut-off sharpnesses (β) of the particle spectra.
The simulations were performed by using different CR composition distributions (protons, CNO, Fe) and different sharpness values ranging from β = 0.5 to β = 1.5.

The results show that, in the cases studied here, CTAO will increase the sensitivity to the spectral shape of γ-rays. This allows us to distinguish protons from heavy CRs and obtain information on β values and therefore on different acceleration scenarios.
Improving Hydrogen Production in Plasma-Assisted Bi-Reforming of Methane: Experimental Study in Rotating Gliding Arc Plasma Reactor
Authors: Pathak Ram Mohan , Rao Lakshminarayana 
Published: February 2025

Abstract
This research examines how different flow regimes transient, and turbulent affect the electrical and optical properties and Hydrogen production of Bi reforming of methane (CO2/CH4/H2O) in a rotating gliding arc (RGA) reactor. The f
arc parameter was measured using a high-speed camera and Fast Fourier Transform voltage analysis. Optical Emission Spectroscopy captured the RGA’s visible emission spectrum, while the rotational temperature was determined via C2 Swan band analysis using SPECAIR. Gas Chromatography with thermal conductivity detector and flame Ionization Detector determined the product gas composition. Different operating parameters, including the RGA swirl hole diameter (1 mm), steam to carbon (S/C) ratios (0.33 and 0.66), and flow rates varying from 6.7 to 40 SLPM, were tested to improve H2 and CO production. At 6.7 SLPM with S/C0.33, maximum H2 and CO production was 3.4% and 4.2% while at 8 SLPM with S/C0.66 maximum H2 and CO production was 3.9% and 5%. Increasing Q to 37.5 SLPM with S/C0.33 reduced H2 and CO production to 0.7%, and 1.7% while at 40 SLPM and S/C0.66, H2 and CO production reduced to 0.8% and 2.0%, due to lower residence time. These findings are essential for scaling up and optimizing the RGA reactor for H2 production.
Exploring waste heat recovery in hydrogen internal combustion engine buses for absorption air conditioning
Authors: Li Zhiyong , Hou Jingxin 
Published: February 2025

Abstract
This paper presents the recovery of waste heat in hydrogen internal combustion engine (ICE) buses for absorption air conditioning, specifically through the integration of a double-effect lithium bromide absorption cooling system. The study reveals significant potential for effectively harnessing waste heat to meet cabin cooling demands. An energy balance analysis indicates that the waste heat generated by hydrogen ICE buses can adequately satisfy cooling load requirements when ambient temperatures are below 34°C, and remains capable of addressing over 80% of the cooling demand as temperatures rise between 35°C and 40°C, with a decrease in system coverage of approximately 4% for each 1°C increase in ambient temperature. Additionally, large buses exhibit superior energy efficiency compared to their medium-sized buses. To address onboard space limitations, a split lithium bromide absorption cooling system is proposed, featuring a rooftop cooling tower and compact integration of essential components within the bus. This configuration minimizes disruption to passenger space while maintaining system efficacy. The case study further demonstrates that the system can be implemented in large buses without compromising spatial efficiency, achieving a well-balanced combination of operational performance and passenger comfort while remaining compatible with urban transport and operational constraints.
Numerical investigation on the dry low NOx of hydrogen combustion
Authors: Tamang Sajan , Park Heesung 
Published: February 2025

Abstract
Globally, energy is predominantly generated through the combustion of fossil fuels. However, the emissions from these fuels severely impact the ecological balance and environment. As a result, there is a growing emphasis on clean and renewable energy sources as alternatives. Hydrogen is a promising and clean energy source for gas turbines, transportation, and industrial applications. Nevertheless, due to significant differences in hydrogen’s thermophysical properties, it cannot be directly integrated into conventional combustion systems. Therefore, a specialized micromix combustion model must be developed to achieve stable combustion with low dry NOx emissions. In this study, a novel micromix combustor is developed based on the cross-flow mixing of air and injected hydrogen fuel. Under this concept, hydrogen combustion occurs through diffusion-type flames, with the reaction taking place in a very short time. This micromix combustor design ensures inherently stable combustion, resistant to flashback while maintaining low dry NOx emissions. The results indicate that the stability of the flame structure and thermal NOx emissions are controlled by the operating equivalence ratios. A stable hydrogen flame was particularly formed in the shear regions between the two vortices. Thermal NOx generation was strongly influenced by the flame front temperature, with measurements ranging from approximately 0.66 to 11.14 ppm (at 15% oxygen concentration). Consequently, thermal NOx emissions increased by up to 16 times under an equivalence ratio of 0.5.
State of Health Prediction for Lithium-Ion Battery Pack Using a Shared Embedding Layer-Based Quantum Long Short-Term Memory with Transfer Learning
Authors: Wang Fu-Kwun , Kebede Getnet Awoke , Woldegiorgis Bereket Haile 
Published: February 2025

Abstract
In this paper, an approach leveraging a shared embedding layer-based quantum long short-term memory (QLSTM) neural network and transfer learning technique is proposed to enhance the accuracy of lithium-ion battery (LIB) pack degradation predictions. The model is especially applied for lithium-ion battery (LIB) aging prognosis when there is limited real-time training data. The framework integrates various methods, including a shared linear embedding layer, QLSTM algorithm, and sliding window techniques. It employs a QLSTM with embedding layers to compress feature dimensions and make predictions. The model is trained offline using historical pack capacity degradation data from a source domain (LIB1) and then transferred and fine-tuned to a target domain (LIB2). Comparative experiments demonstrate the robustness of the proposed model, with the root mean square errors (RMSEs) of pack LIB capacity predictions consistently below 0.002 as the training data increases. The proposed approach exhibits promising results in improving the accuracy of pack capacity degradation predictions for LIB aging prognosis.
Laser surface modification on titanium bipolar plate for resistance enhancement of bonding interface to thermal and acidic corrosion
Authors: Min Junying , Zhang Xinyi , Lin Jianping , Wan Hailang 
Published: February 2025

Abstract
Adhesive bonding has become one of the joining and sealing technologies for titanium bipolar plates in proton exchange membrane fuel cells. However, the bonding interface of titanium bipolar plates is prone to fracture due to the effect of thermal-acidic environment inside the fuel cell, making it crucial to ensure the service stability of bonding interface. This study applied laser surface modification to addressing this challenge, and further investigated the effect of laser power and overlap ratio on the corrosion resistance of titanium bonding interface under thermal-acidic environment of 80 °C and 5 ppm fluoride ion. It is found that laser surface modification with higher overlap ratio fabricates deeper and denser pits on titanium surface, and with higher laser power generates complex dendritic structures around the pits. These factors effectively inhibit the degradation of bonding interface under corrosion in the thermal-acidic environment. The strength degradation was decreased to 18.9 % with residual strength maintaining above 20 MPa at optimal process parameters of 6 W power and 50 % overlap ratio. Additionally, the study revealed that corrosion temperature significantly affected the strength degradation of untreated joints, while caused negligible effect on the strength degradation of laser-treated joints. Higher temperature accelerated the diffusion of corrosive ions along the untreated interface, whereas the penetration of corrosive ions was prevented by laser-treated interface. Moreover, the dominant role of water was found for the degradation of titanium bonding interface.
Semantic-Based Link Prediction in Dynamic Technology Innovation Networks
Authors: Teng Fei , Sun Yuling , Wang Lu , Liu Jiangfeng 
Published: February 2025

Abstract
Technological innovation networks are essential for advancing technologies and fostering scientific breakthroughs. However, a significant challenge remains in their limited capacity to accurately capture semantic relationships and predict future technological developments. To address this, a dynamic innovation network for the technologies is constructed by integrating the LDA topic model and the word2vec algorithm, allowing for the exploration of its evolving patterns. Then, by optimizing the link prediction algorithm, potential relationships within the network are identified, revealing under-explored technological development directions. The results, focusing on hydrogen energy technology, indicate that technologies focused on enhancing the efficiency and performance of power systems, improving the reliability of hydrogen energy systems, and advancing high-efficiency electrolysis-based hydrogen production and supply systems exhibit sustained research momentum. Notably, high-efficiency electrolysis-based hydrogen production systems have experienced significant growth in research attention in recent years. It is anticipated that future advancements will involve greater integration and relevance of technologies aimed at improving power system efficiency, potentially catalyzing a leap development of hydrogen energy technologies.
Exploring the Aging Dynamics of Lithium-Ion Batteries for Enhanced Lifespan Understanding
Authors: Madani Seyed Saeed , Allard François , Shabeer Yasmin , Fowler Michael , Panchal Satyam , Ziebert Carlos , Mekhilef Saad , Dou Shi Xue , See Khay , Wang Zolu 
Published: February 2025

Abstract
This review examines the aging mechanisms and performance decline of lithium-ion batteries under various conditions, focusing on temperature effects, charge/discharge efficiency, and operational limits. It covers high-temperature aging and its impact on the solid electrolyte interphase (SEI) layer, as well as thermal runaway risks. Low-temperature aging is also discussed, emphasizing reversible capacity loss, increased resistance, and lithium plating. The review addresses degradation from overcharge/over-discharge scenarios and explores coulombic efficiency (CE) degradation and its link to capacity loss. By synthesizing current research, it provides insights into optimizing battery management and enhancing performance.