bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phenotypic segregation of seedling UCB-1 hybrid pistachio rootstock
Authors: Jacygrad Ewelina , Preece John E. , Palmer William J. , Michelmore Richard , Golino Deborah 
Published: November 2019

AbstractKey messageThe growth of UCB-1 pistachio rootstock seedlings in the earliest years is a poor predictor of subsequent growth. Therefore, rogueing during the 1st years of growth is not effective.AbstractThe UCB-1 hybrid, produced from a controlled cross betweenPistacia atlantica(female) andP. integerrima(male), is the main pistachio rootstock used in the USA. Variation has been observed in orchards planted with seedling UCB-1 rootstocks for over 20 years. Reduced vigor and stunting of some trees are of particular concern to growers due to decreased nut yield. This study was conducted to better understand the growth of non-grafted UCB-1, as well as between UCB-1 rootstock andPistacia verascions in commercial orchards. Phenotypic traits were evaluated in the non-grafted orchard. Grafted tree data were collected for bothP. verafemale scions and their UCB-1 seedling rootstocks in commercial orchards. The uniformity of tree height, trunk caliper, and canopy volume decreased annually during the first 5 years of growth. Individual tree growth was not linear and was poorly synchronized among siblings, causing the population to become increasingly less uniform as it aged. Consequently, growth in the earliest years is a poor predictor of subsequent growth. The strongest correlation was between growth parameters during the later years. There was a significant correlation between rootstock and scion caliper of the grafted trees in commercial orchards, with the least vigorous rootstocks producing the least vigorous scions. These data confirm the need to reliably rogue out seedlings that later will not be vigorous; however, our data show that rogueing based on the 1st years of growth is ineffective. This study suggests the need to develop predictive molecular markers for rootstock vigor.
External quality assessment for molecular diagnostic laboratories in Belgium: Can we improve it?
Authors: Dufraing Kelly , Lierman Els , Vankeerberghen Anne , Franke Sabine , Dequeker Els 
Published: November 2019

AbstractExternal quality assessment (EQA) is an essential part of performance monitoring for molecular laboratories. At the moment, a national law regulates participation in EQA schemes for clinical biology and pathology in Belgium. This study aimed (1) to get insights on how laboratories organize their EQA participation, (2) to poll satisfaction with the current situation (selection of EQA programs in advance by a governmental body), (3) to provide guidance for choosing the most relevant EQA provider and (4) to propose a new model for national performance monitoring. A survey was sent to Belgian laboratories performing molecular tests in the field of microbiology, hematology and pathology with (1) general questions on how they select an EQA provider and (2) their satisfaction of each provider. In total, 25 molecular laboratories [microbiology (N = 13), hematology (N = 8) and pathology (N = 4)] from 14 different hospitals completed the survey regarding their EQA organization. All three laboratory groups indicated to prefer EQA schemes using real patient materials as well as those with varying targets and concentrations. For molecular microbiology and hematology, schemes with a syndromic approach are sought. Since annual participation in EQA becomes burdensome in most laboratories, this paper also offers a risk-based strategy for determining the participation frequency. Based on the needs of Belgian laboratories, three proposals were made: (1) for the proper selection of an EQA scheme, (2) for determining the minimal participation frequency and (3) for the national organization of EQA schemes.
The Mediating Role of Depression in the Relationship Between Body Image Dissatisfaction and Cyberbullying Perpetration
Authors: Balta Sabah , Emirtekin Emrah , Kircaburun Kagan , Griffiths Mark D. 
Published: November 2019

AbstractPreliminary evidence suggests that psychopathological factors (e.g., depression) are associated with higher engagement in cyberbullying perpetration, and those with elevated body image dissatisfaction (BID) are more susceptible to depression. However, the possible impact of body image dissatisfaction (BID) on cyberbullying remains untested. The present study examined the direct and indirect relationships of BID with cyberbullying via depression among a sample of 507 university students (mean age, 21.37 years; range 18–44 years). t tests showed that males had a higher prevalence of cyberbullying than females. Structural equation modeling indicated that BID was directly and indirectly associated with cyberbullying via depression among the total sample and males. However, BID was only indirectly related to cyberbullying via depression among females. Depression fully explained the relationship between BID and cyberbullying among females, although there were additional mediating factors between BID and cyberbullying among males. The findings are in accordance with theoretical models suggesting that individuals’ personal characteristics including psychopathological factors are associated with cyberbullying. Furthermore, males attempt to cope with their body image–related psychopathology with more externalizing behaviors than females.
Risk Stratification for Sudden Cardiac Death in Non-Ischaemic Dilated Cardiomyopathy
Authors: Akhtar M. , Elliott P. M. 
Published: November 2019

Abstract
Purpose of Review
Non-ischaemic dilated cardiomyopathy (DCM) occurs in 1 in 2500 individuals in the general population and is associated with considerable morbidity and mortality. Studies involving large numbers of unselected DCM patients have led to consensus guidelines recommending implantable cardioverter-defibrillator (ICD) implantation for protection against sudden cardiac death (SCD) in those with LVEF ≤35%. The purpose of this article is to review the literature for other potential markers including serological, electrocardiographic, echocardiographic, cardiac magnetic resonance, ambulatory ECG and genetic data, to highlight other potential markers that may optimise risk stratification for SCD in this cohort and thereby allow a more personalized approach to ICD-implantation.

Recent Findings
Recent studies including the Danish study to assess the efficacy of ICDs in patients with non-ischemic systolic heart failure on mortality (DANISH) trial have questioned the benefits of ICD implantation in this group of patients with no changes in all-cause mortality. Recent pooled cohorts of patients with genetic DCM and in particular in those with Lamin A/C (LMNA) mutations have identified patients at increased risk of SCD and allowed the creation of algorithms to prognosticate SCD risk in mutation carriers. Furthermore, genetic testing has identified other DCM-causing genes including filamin C (FLNC) and RBM20 which may be associated with higher rates of ventricular arrhythmia.

Summary
To date, risk-stratification for SCD has been hampered by the utilisation of heterogenous subsets of idiopathic DCM patients and by use of static risk models where predictions are based on a single time point with a lack of consideration of disease progression. The current focus of personalised risk-stratification for SCD is shifting towards better characterisation of underlying DCM aetiology and the development of multi-parametric risk-stratification models that incorporate time-dependent disease characteristics and novel biomarkers.
An elderly man with progressive focal nodular hyperplasia
Authors: Hamada Koichi , Saitoh Satoshi , Nishino Noriyuki , Fukushima Daizo , Techigawara Kae , Koyanagi Ryota , Horikawa Yoshinori , Shiwa Yoshiki , Sakuma Hideo , Kondo Fukuo 
Published: November 2019

AbstractPatients with focal nodular hyperplasia (FNH) develop benign hepatocellular nodules. FNH most frequently occurs in young women. There are no reports of the onset of FNH in elderly men. We report a case of FNH in an elderly man, whose nodules increased in number and size. The patient underwent surgery for carcinoma of the left renal pelvis at 69 years of age; no liver masses were noted on yearly follow-up contrast-enhanced computed tomography (CECT). Ten years later, CECT revealed a hepatic mass, and magnetic resonance imaging suggested FNH. The nodules increased in number and size in subsequent follow-up examinations.
How Uncertain is the Survival Extrapolation? A Study of the Impact of Different Parametric Survival Models on Extrapolated Uncertainty About Hazard Functions, Lifetime Mean Survival and Cost Effectiveness
Authors: Kearns Ben , Stevens John , Ren Shijie , Brennan Alan 
Published: November 2019

AbstractBackground and ObjectiveThe extrapolation of estimated hazard functions can be an important part of cost-effectiveness analyses. Given limited follow-up time in the sample data, it may be expected that the uncertainty in estimates of hazards increases the further into the future they are extrapolated. The objective of this study was to illustrate how the choice of parametric survival model impacts on estimates of uncertainty about extrapolated hazard functions and lifetime mean survival.MethodsWe examined seven commonly used parametric survival models and described analytical expressions and approximation methods (delta and multivariate normal) for estimating uncertainty. We illustrate the multivariate normal method using case studies based on four representative hypothetical datasets reflecting hazard functions commonly encountered in clinical practice (constant, increasing, decreasing, or unimodal), along with a hypothetical cost-effectiveness analysis.ResultsDepending on the survival model chosen, the uncertainty in extrapolated hazard functions could be constant, increasing or decreasing over time for the case studies. Estimates of uncertainty in mean survival showed a large variation (up to sevenfold) for each case study. The magnitude of uncertainty in estimates of cost effectiveness, as measured using the incremental cost per quality-adjusted life-year gained, varied threefold across plausible models. Differences in estimates of uncertainty were observed even when models provided near-identical point estimates.ConclusionsSurvival model choice can have a significant impact on estimates of uncertainty of extrapolated hazard functions, mean survival and cost effectiveness, even when point estimates were similar. We provide good practice recommendations for analysts and decision makers, emphasizing the importance of considering the plausibility of estimates of uncertainty in the extrapolated period as a complementary part of the model selection process.
An international, interprofessional investigation of the self-reported podcast listening habits of emergency clinicians: A METRIQ Study
Authors: Thoma Brent , Goerzen Scott , Horeczko Timothy , Roland Damian , Tagg Andrew , Chan Teresa M , Bruijns Stevan , Riddell Jeff ,   The METRIQ Podcast Study Collaborators
Published: November 2019

ABSTRACTObjectivesPodcasts are increasingly being used for medical education. A deeper understanding of usage patterns would inform both producers and researchers of medical podcasts. We aimed to determine how and why podcasts are used by emergency medicine and critical care clinicians.MethodsAn international interprofessional sample (medical students, residents, physicians, nurses, physician assistants, and paramedics) was recruited through direct contact and a multimodal social media (Twitter and Facebook) campaign. Each participant completed a survey outlining how and why they utilize medical podcasts. Recruitment materials included an infographic and study website.Results390 participants from 33 countries and 4 professions (medicine, nursing, paramedicine, physician assistant) completed the survey. Participants most frequently listened to medical podcasts to review new literature (75.8%), learn core material (75.1%), and refresh memory (71.8%). The majority (62.6%) were aware of the ability to listen at increased speeds, but most (76.9%) listened at 1.0 x (normal) speed. All but 25 (6.4%) participants concurrently performed other tasks while listening. Driving (72.3%), exercising (39.7%), and completing chores (39.2%) were the most common. A minority of participants used active learning techniques such as pausing, rewinding, and replaying segments of the podcast. Very few listened to podcasts multiple times.ConclusionsAn international cohort of emergency clinicians use medical podcasts predominantly for learning. Their listening habits (rarely employing active learning strategies and frequently performing concurrent tasks) may not support this goal. Further exploration of the impact of these activities on learning from podcasts is warranted.
Feasibility of connecting regional research programs to national multisite trials emanating from the CTSA Trial Innovation Network
Authors: Hassell Laurie , Gregor Charlie , Melvin Ann , Goss Christopher , Coker Robert H. , Laukes Cindi , Albritton Sandra , Brant Jeannine , Amoroso Paul , Whitener Nichole , Tuttle Katherine R. 
Published: November 2019

AbstractA collaborative research model was developed and tested to enable regional healthcare systems to join multisite clinical trials emanating from the Clinical and Translational Science Award (CTSA) Trial Innovation Network (TIN) by the Institute of Translational Health Sciences at the University of Washington and the Northwest Participant and Clinical Interactions (NW PCI) Network. The NW PCI is a collaborative group of regional research programs located at medical centers, healthcare systems, and universities across Washington, Wyoming, Alaska, Montana, and Idaho. This article describes the purpose, development, barriers, and initial experience with feasibility assessment for TIN-supported studies in the NW PCI. The tools and processes of the NW PCI Network were adapted to enable network sites to assess studies for clinical relevance and feasibility. Seven of seventeen TIN-supported studies were reviewed for consideration; three of which resulted in successful completion of study documentation for site selection by NW PCI sites. The NW PCI/TIN model can be adapted by other CTSAs to increase involvement of regional research programs in national multisite clinical research studies. Barriers to expanding TIN-supported trials to regional networks include short timelines for study document submissions, insufficient site reimbursement rates, and non-feasible study designs.
The Twilight of the Two-State Solution in Israel-Palestine: Shared Sovereignty and Nonterritorial Autonomy as the New Dawn
Authors: Nimni Ephraim 
Published: November 2019

AbstractThis article analyzes the international consensus on the Israeli-Palestinian conflict that there should be a two state solution and finds it unworkable on several counts. The conflict has no territorial solution: high population density makes partition impossible without leaving unwanted pockets of one people in the territory of the other; it is not possible for any Israeli government to dismantle settlements in the West Bank without causing a civil war; and in such a small and overcrowded territory, it is not feasible to have monocultural nation-states when the population is now evenly divided between the two conflicting national communities that reside in overlapping areas. Demographic forecasts show in the short term, a decrease in the proportion of Israeli Jews and an increase in the proportion of Palestinians. In the face of this stalemate, the article recalls the 90-year-old proposal by enlightened Jewish personalities to create a binational state under the modality of national-cultural autonomy. Furthermore, and paradoxically, in a reversal of the situation 90 years ago, Palestinian Israeli citizens are slowly creating a bottom-up series of autonomous communal organizations that provide self-government without territorial control, a model for nonterritorial autonomy in a manner that reminds of the earlier proposals of the Jewish personalities. The article concludes that this could potentially be a way out of this stalled and protracted conflict. A plurinational state in Israel-Palestine based on the model of National Cultural Autonomy with shared sovereignty and collective rights for all communities.
Educational level and its relationship with body height and popliteal height in Chilean male workers
Authors: Viviani Carlos , Castellucci Héctor Ignacio , Arezes Pedro , Bartsch Ángelo , Bragança Sara , Molenbroek Johan F. M. , Martínez Marta , Aparici Verónica 
Published: November 2019

AbstractA secular trend in body height has been experienced in many nations and populations, hypothesized to be the result of better living conditions. Educational level has been shown to be closely associated with body height. This study examined the changes in body height and popliteal height in a group of adult Chilean male workers by age cohort and the relationship of these with educational level. The body heights and popliteal heights of 1404 male workers from the Valparaíso and Metropolitan regions of Chile were measured in 2016. The sample was grouped by level of education (primary, secondary, technical and university) and age (21–30, 31–40 and 41–50 years). Robust ANOVA and post-hoc analyses using a one-step modified M-estimation of location were conducted based on bootstrap resampling. Both body height and popliteal height increased from the older to the younger age cohort. The largest increase was from the 41–50 to the 21–30 group, with a 1.1% increase in body height and 1.7% increase in popliteal height. When educational level was introduced into the analysis there was a marked increase in both body height and popliteal height for each cohort, but only in primary- and secondary-educated workers. Despite showing an overall increase in body height and popliteal height, younger workers with the highest levels of education showed fewer differences between them than did older workers with less education. The differences were larger in the older than in the younger cohorts. Similarly, this trend was less clear in workers with higher levels of education (technical and university), probably because of a dilution effect caused by increased access to higher education by workers in the lower income quintiles.
Sentence repetition and non-word repetition in early total French immersion
Authors: Scheidnes Maureen 
Published: November 2019

AbstractRecent research has focused on bilingual children’s performance on non-word repetition (NWR) and sentence repetition (SR) tasks, but it remains unclear how their scores can be expected to vary as a function of language exposure, which creates challenges for developing age-appropriate performance expectations. With the goal of examining the impact of limited language exposure on these tasks, French NWR and SR performance from 33 first graders (mean age 6 years, 10 months) in early total French immersion in English-speaking Canada was compared to prior work on bilinguals acquiring French in France. With a mean length of exposure of 1 year, 7 months, but a mean cumulative length of exposure of only 3 months, the children in immersion have much less daily exposure to French than the bilinguals in France. The results showed that children in immersion patterned with the other bilinguals for NWR, but had much weaker SR performance. Within-subjects analyses revealed that, for SR, the children in immersion had stronger scores on wh-questions and relative clauses, which suggests that these structures may be less sensitive to language exposure.
Adaptive Sliding Mode Impedance Control of Single-Link Flexible Manipulators interacting with the Environment at an Unknown Intermediate Point
Authors: Fayazi Ali , Pariz Naser , Karimpour Ali , Feliu-Batlle V. , HosseinNia S. Hassan 
Published: November 2019

SUMMARYThis paper proposes an adaptive robust impedance control for a single-link flexible arm when it encounters an environment at an unknown intermediate point. First, the intermediate collision point is estimated using a collision detection algorithm. The controller, then, switches from free to constrained motion mode. In the unconstrained motion mode, the exerted force to environment is nearly zero. Thus, the reference trajectory is a prescribed desired trajectory in position control. In the constrained motion mode, the reference trajectory is determined by the desired target dynamic impedance. The simulation results demonstrate the efficiency of proposed control scheme.
How do context variables affect food insecurity in Mexico? Implications for policy and governance
Authors: Vilar-Compte Mireya , Gaitán-Rossi Pablo , Flores Diana , Pérez-Cirera Vanessa , Teruel Graciela 
Published: November 2019

AbstractObjective:To assess, from a systems perspective, how climate vulnerability and socio-economic and political differences at the municipal and state levels explain food insecurity in Mexico.Design:Using a cross-sectional design with official secondary data, we estimated three-level multinomial hierarchical linear models.Setting:The study setting is Mexico’s states and municipalities in 2014.Participants:Heads of households in a representative sample of the general population.Results:At the municipal level, vulnerability to climate disasters and a poverty index were significant predictors of food insecurity after adjusting for household-level variables. At the state level, gross domestic product and the number of nutrition programmes helped explain different levels of food insecurity but change in political party did not. Predictors varied in strength and significance according to the level of food insecurity.Conclusions:Findings evidence that, beyond food assistance programmes and household characteristics, multiple variables operating at different levels – like climate vulnerability and poverty – contribute to explain the degree of food insecurity. Food security governance is a well-suited multisectoral approach to address the complex challenge of hunger and access to a nutritious diet.
Groundwater Variations From Autocorrelation and Receiver Functions
Authors: Kim D. , Lekic V. 
Published: November 2019

AbstractUsing a 20‐year continuous broadband record and two independent single‐station techniques—ambient noise autocorrelation and receiver functions—we document a relationship between subsurface seismic response and groundwater levels (GWLs) in the Gulf Coast Aquifer System of southern Texas. We find that a surge of GWL following three consecutive hurricanes and documented at an adjacent monitoring well is accompanied with changes in receiver function power spectra and ambient noise autocorrelations. Using a simple physical model, we show that GWL changes should affect P‐ (VP) more strongly than S‐wave (VS) velocities, consistent with our observations and previous ones based on inter‐station correlations. Agreement between receiver function and ambient noise analyses shows that both can be used to reliably estimate temporal changes in subsurface properties on long timescales. Due to their sensitivity to VP, single‐station techniques respond more strongly to GWL changes, making them useful for characterizing and monitoring aquifer systems.