bluuebunny/crossref_metadata_2025_split huggingface dataset:
Procès climatiques : le magistrat (à nouveau) au cœur du droit
Authors: Papaux Alain 
Published: December 2019

Les procès climatiques se fondent souvent sur les Principes généraux, lesquels, de par leur nature vague, délèguent de facto la substance du droit de l'environnement au magistrat dont la parole devient alors quasi existentielle. Pareille gravité s'entend déjà dans « pollution » désignant, à l'origine, la profanation du sacré ; dans sa parole résonne alors toute une anthropologie des droits humains menacée par les « actions par omission » de l'homme lui-même. Elle ravive aussi le ressort sacré du politique : l'auto-fondation des institutions, à la J.-J. Rousseau. Mais l'entrée en Anthropocène l'oblige à reconfigurer la liberté.
L'indépendance de la justice au Sénégal
Authors: Teliko Souleymane 
Published: December 2019

Malgré la constitution sénégalaise de 1963 qui consacre le principe de l'indépendance du « pouvoir judicaire », force est de constater qu'en réalité il n'en est rien. Le pouvoir exécutif domine le Conseil supérieur de la magistrature et reste le chef du parquet d'un double point de vue fonctionnel et statutaire. Cet article fait des propositions afin de renforcer l'indépendance de la justice : autonomie plus grande du CSM, statut du parquet rénové, gestion des juridictions mieux adaptées à leurs besoins sont ses thèmes principaux de réforme.
(Faire) participer en tant qu’indigènes. Gouvernement et contestation dans les usages de la consultation en Amazonie – Pérou
Authors: Buu-Sao Doris 
Published: December 2019

À partir d’une ethnographie de la « consultation préalable » au Pérou, cet article interroge l’ambivalente ethnicisation de dispositifs participatifs destinés aux groupes « indigènes ». Il analyse dans un premier temps le rôle joué par la consultation préalable dans le système péruvien de gestion des conflits sociaux ciblant les groupes indigènes, à travers la production de catégories ethno-raciales neutralisées. Dans un second temps, il souligne la capacité des participant·e·s à repolitiser ces catégories, en fonction des socialisations à l’action contestataire qui les caractérisent. Mais celles-ci restent inégales d’une personne à l’autre, conduisant à mieux saisir la force pacificatrice de la consultation préalable, qui a finalement marginalisé les plus réfractaires aux catégories prescrites par le format consultatif.
A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome
Authors: Bhatta Ankit , Atianand Maninjay , Jiang Zhaozhao , Crabtree Juliet , Blin Juliana , Fitzgerald Katherine A. 
Published: December 2019

Abstract
Functional peptides encoded by short open reading frames are emerging as important mediators of fundamental biological processes. In this study, we identified a micropeptide produced from a putative long noncoding RNA (lncRNAs) that is important in controlling innate immunity. By studying lncRNAs in mice macrophages, we identified lncRNA 1810058I24Rik, which was downregulated in both human and murine myeloid cells exposed to LPS as well as other TLR ligands and inflammatory cytokines. Analysis of lncRNA 1810058I24Rik subcellular localization revealed that this transcript was localized in the cytosol, prompting us to evaluate its coding potential. In vitro translation with 35S-labeled methionine resulted in translation of a 47 aa micropeptide. Microscopy and subcellular fractionation studies in macrophages demonstrated endogenous expression of this peptide on the mitochondrion. We thus named this gene mitochondrial micropeptide-47 (Mm47). Crispr–Cas9–mediated deletion of Mm47, as well as small interfering RNA studies in mice primary macrophages, showed that the transcriptional response downstream of TLR4 was intact in cells lacking Mm47. In contrast, Mm47-deficient or knockdown cells were compromised for Nlrp3 inflammasome responses. Activation of Nlrc4 or Aim2 inflammasomes were intact in cells lacking Mm47. This study therefore identifies, to our knowledge, a novel mitochondrial micropeptide Mm47 that is required for the activation of the Nlrp3 inflammasome. This work further highlights the functional activity of short open reading frame–encoded peptides and underscores their importance in innate immunity.
A Case Report of a Cutaneous Mucinous Reaction Associated with Erlotinib Therapy Used in the Treatment of Metastatic Tonsillar Sinus Squamous Cell Carcinoma
Authors: Freemyer Benjamin D , Cabala Torres-Carlos A , Patel Anisha B 
Published: December 2019

Abstract
Cutaneous mucinoses are a diverse group of diseases that are occasionally seen in the context of an adverse drug reaction. We report the case of a 59-year-old male who presented with an asymptomatic, acneiform rash on his forehead, scalp, nose, upper chest, and upper back that had developed after treatment with erlotinib therapy used in the treatment of metastatic tonsillar sinus squamous cell carcinoma. Biopsy of these lesions demonstrated atypical histology that had features of both follicular mucinosis and myxedema. This histologic phenomenon is a rare drug reaction that has not previously been described in association with erlotinib.
Fibulin-3 serum and urine levels in the diagnosis and severity assessment of primary knee osteoarthritis
Authors: Nassif Mary 
Published: December 2019

ObjectivesOsteoarthritis (OA) is the most widespread joint disease and is a major cause of joint pain and disability in the middle aged and elderly population. The diagnosis of OA is based on clinical and radiographic changes that occur late after disease progression, and hence does not allow early detection of structural damage. Therefore, there is an acute need for reliable biochemical markers that can facilitate its earlier diagnosis. This study was commenced to identify fibulin-3 levels in serum and urine of patients with primary knee OA and to investigate their relationship with severity of the disease.Material and methodsFifty female patients with primary knee OA were compared to 25 healthy female controls. Fibulin-3 in serum and urine were measured using enzyme-linked immunosorbent assay (ELISA). Severity of knee pain was assessed by the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index and the Knee Outcome Survey Activities of Daily Living (KOS-ADL) scale. Radiographic grading of knee OA was performed by Kellgren-Lawrence (K-L) criteria.ResultsSerum and urine fibulin-3 were higher in patients (286.00 ±145.00 ng/ml and 104.60 ±32.73 ng/ml, respectively) than in controls (26.00 ±5.77 ng/ml and 13.60 ±4.21 ng/ml, respectively). Fibulin-3 in serum and urine correlated (p < 0.001) with each other (r = 0.930) and with the severity of knee pain by WOMAC index (r = 0.909 and 0.928, respectively), inversely correlated with KOS-ADL (r = –0.913 and –0.953, respectively), and with radiographic grading of K-L (r = 0.855 and 0.875, respectively).ConclusionsFibulin-3 serves as a biomarker of knee OA disease severity and could predict disease progression. Assessing urine fibulin-3 could be an applicable and easy method to diagnose knee OA and to follow up disease progression.
Ability of a soil–vegetation–atmosphere transfer model and a two-source energy balance model to predict evapotranspiration for several crops and climate conditions
Authors: Bigeard Guillaume , Coudert Benoit , Chirouze Jonas , Er-Raki Salah , Boulet Gilles , Ceschia Eric , Jarlan Lionel 
Published: December 2019

Abstract. The heterogeneity of Agroecosystems, in terms of hydric conditions, crop types and states, and meteorological forcing, is difficult to characterize precisely at the field scale over an agricultural landscape. This study aims to perform a sensitivity study with respect to the uncertain model inputs of two classical approaches used to map the evapotranspiration of agroecosystems: (1) a surface energy balance (SEB) model, the Two-Source Energy Balance (TSEB) model, forced with thermal infrared (TIR) data as a proxy for the crop hydric conditions, and (2) a soil–vegetation–atmosphere transfer (SVAT) model, the SEtHyS model, where hydric conditions are computed from a soil water budget. To this end, the models' skill was compared using a large and unique in situ database covering different crops and climate conditions, which was acquired over three experimental sites in southern France and Morocco. On average, the models provide 30 min estimations of latent heat flux (LE) with a RMSE of around 55 W m−2 for TSEB and 47 W m−2 for SEtHyS, and estimations of sensible heat flux (H) with a RMSE of around 29 W m−2 for TSEB and 38 W m−2 for SEtHyS. A sensitivity analysis based on realistic errors aimed to estimate the potential decrease in performance induced by the spatialization process. For the SVAT model, the multi-objective calibration iterative procedure (MCIP) is used to determine and test different sets of parameters. TSEB is run with only one set of parameters and provides acceptable performance for all crop stages apart from the early growing season (LAI < 0.2 m2 m−2) and when hydric stress occurs. An in-depth study on the Priestley–Taylor key parameter highlights its marked diurnal cycle and the need to adjust its value to improve flux partitioning between the sensible and latent heat fluxes (1.5 and 1.25 for France and Morocco, respectively). Optimal values of 1.8–2 were highlighted under cloudy conditions, which is of particular interest due to the emergence of low-altitude drone acquisition. Under developed vegetation (LAI > 0.8 m2 m−2) and unstressed conditions, using sets of parameters that only differentiate crop types is a valuable trade-off for SEtHyS. This study provides some scientific elements regarding the joint use of both approaches and TIR imagery, via the development of new data assimilation and calibration strategies.
The FluxEngine air–sea gas flux toolbox: simplified interface and extensions for in situ analyses and multiple sparingly soluble gases
Authors: Holding Thomas , Ashton Ian G. , Shutler Jamie D. , Land Peter E. , Nightingale Philip D. , Rees Andrew P. , Brown Ian , Piolle Jean-Francois , Kock Annette , Bange Hermann W. , Woolf David K. , Goddijn-Murphy Lonneke , Pereira Ryan , Paul Frederic , Girard-Ardhuin Fanny , Chapron Bertrand , Rehder Gregor , Ardhuin Fabrice , Donlon Craig J. 
Published: December 2019

Abstract. The flow (flux) of climate-critical gases, such as carbon dioxide
(CO2), between the ocean and the atmosphere is a fundamental component
of our climate and an important driver of the biogeochemical systems within
the oceans. Therefore, the accurate calculation of these air–sea gas fluxes
is critical if we are to monitor the oceans and assess the impact that these
gases are having on Earth's climate and ecosystems. FluxEngine is an open-source software toolbox that allows users to easily perform calculations of
air–sea gas fluxes from model, in situ, and Earth observation data. The original
development and verification of the toolbox was described in a previous
publication. The toolbox has now been considerably updated to allow for its use
as a Python library, to enable simplified installation, to ensure verification of its
installation, to enable the handling of multiple sparingly soluble gases, and to enable the
greatly expanded functionality for supporting in situ dataset analyses. This new
functionality for supporting in situ analyses includes user-defined grids, time
periods and projections, the ability to reanalyse in situ CO2 data to a
common temperature dataset, and the ability to easily calculate gas fluxes
using in situ data from drifting buoys, fixed moorings, and research cruises. Here
we describe these new capabilities and demonstrate their application
through illustrative case studies. The first case study demonstrates the
workflow for accurately calculating CO2 fluxes using in situ data from four
research cruises from the Surface Ocean CO2 ATlas (SOCAT) database. The
second case study calculates air–sea CO2 fluxes using in situ data from a
fixed monitoring station in the Baltic Sea. The third case study focuses on
nitrous oxide (N2O) and, through a user-defined gas transfer
parameterisation, identifies that biological surfactants in the North
Atlantic could suppress individual N2O sea–air gas fluxes by up to
13 %. The fourth and final case study illustrates how a dissipation-based
gas transfer parameterisation can be implemented and used. The updated
version of the toolbox (version 3) and all documentation is now freely
available.
Development of gluten-free non-yeasted dough structure as factor of bread quality formation
Authors: Shanina Olga , Galyasnyj Ivan , Gavrysh Tetyana , Dugina Kateryna , Sukhenko Yuriy , Sukhenko Vladyslav , Miedviedieva Natalia , Mushtruk Mikhailo , Rozbytska Tatyana , Slobodyanyuk Natalia 
Published: December 2019

The article is devoted to the study of the influence of hydrocolloids and animal protein concentrates on the formation of the foam-like structure of gluten-free non-yeast dough as the main factor for bread quality formation. The use of CMC in a concentration of 0.5% is found to be appropriate. The bread volume increases to 236 cm3.100g-1 in comparison with the control sample in water – 202 cm3.100g-1. It is proved that the suggested additives in the amounts of 0.5 ‒ 1.0% Helios-11 and 0.5% CMC solution cause 100% resistance of egg white foam. In this case, the foaming ability increases with the addition of Helios-11 only in amounts up to 1.0%, then decreases for higher amounts of Helios-11 or in the presence of CMC. This can be explained by the increase in density of the whipping mass and the ability of both additives to thicken solutions. In the presence of the additives, the foamy texture of the dough changes. The number of large pores (0.7 – 1.5 mm) decreases almost fourfold, and the number of small and very small pores (0.1 ‒ 0.5 mm) increases significantly. The index of form resistance of the control sample is 32, and in the presence of 0.5% CMC with 0.5 ‒ 1.0% APC is 20 ‒ 21, which indicates a decrease in the surface tension of the aqueous solutions with additives, to a large extent, in the case of joint use.
Plum (Prunus rossica Erem.) fruit field and laboratory researces depending on the scion-stock combinations
Authors: Motyleva Svetlana , Upadysheva Galina , Kulikov Ivan , Upadyshev Mikhail , Medvedev Sergei , Panischeva Dariya 
Published: December 2019

The results of the field observations and biochemical researches of plum (PrunusrossicaErem.) fruits grown in the garden of intensive type with agrogenic soil in row spacing are presented in the article. The fruits of plum breeds Kubanskaya kometa и Naidena were gathered from the trees grafted on different stocks. The influene of the stock on the trees productivity, the fruit weight and biochemical structure of the plum fruits were studied. Basic chemical analyses, ascorbic acid concentration, antioxidant activity and fruit ash content were determined. The variation limits of the parameters under study depending on the used stock were shown. The best degustation evaluation parameters were found at the combinations of Kubanskaya kometa on stocks OPA-15-2 and Novinka, Naidena on OPA-15-2 (more than 4,5 points). The high positive correlation (r= 0.92) was marked between solutable solids and sugars content.The researches about the stock influence on the plum fruits titratable acidity change we have not found.The correlation between AA and ascorbic acid content in the fruits was determined (r =0.7). The decreasing row of the elements content in the plum fruits ash is the following: K>P>Mg>Ca>Mo>Cu>S>Ni>Fe≈Si>Mn. The proportion of K is from 18.67 (Naidena/ОРА-15-2) to 27.48 (Kubanskaya kometa/Novinka); P from 3.35 (Kubanskaya kometa/seedlings P.cerasifera Ehrh. to 6.39 (Kubanskaya kometa/Novinka), Mg from 1.11 (Nnaidena/ОРА-15-2) to 2.43 (Naidena/seedlings P.cerasifera Ehrh.) and Ca from 0.39 (Naidena/13-11) to 1.85 (Naidena/OPA-15-2) mass % respectively. The proportion of the rest elements is not more than 1 mass %. Under the OPA-15-2 stock influence the trees productivity and the single fruit weight increased, solutable solids, sugars and ascorbic acid concentration in the fruit in comparison with standard stock by the seedling rootstock of alycha (PrunuscerasiferaEhrh. seedlings). While ingrafting by Novinka stocks the parameters under study decreased.
Deliberative Polling Comes of Age
Authors: Mansbridge Jane 
Published: December 2019

AbstractDemocracy When the People Are Thinking reveals how Deliberative Polls are today becoming embedded to various degrees in the policy processes of some democratic states. Some are legally required and even given close to decisional power at points in the democratic process. Here I warn that the more powerful Deliberative Polls and other minipublics based on “civic lotteries” become—the more they make important decisions instead of merely giving advice—the more they will come under attack from individuals and groups who benefit comparatively from traditional democratic processes. The more they come under attack, the more they will require both normative and perceived legitimacy. Robust legitimacy derives not only from appropriate delegation but from the design and the public presentation of the mini-publics themselves. A contingent analysis argues that the more embedded these institutions become in the state, the more important it will be first to ensure and then to publicize effectively the representativeness of the randomized assembly, the balanced and comprehensive nature of the materials and experts that the citizen deliberators consult, and the quality of the deliberation. Some practical suggestions follow.
Las ciencias cognitivas: preámbulo para comprender el funcionamiento de los esquemas del ser humano
Authors: Escobar Soriano Álvaro Antonio 
Published: December 2019

Varias generaciones de estudios de las ciencias cognitivas, han dado como resultado una amplia cantidad de teorías. En estas, se abordan diferentes aspectos del sistema que permiten al ser humano funcionar en diferentes ambientes. Esto es posible, porque el sistema cerebral es plástico (adaptable), se reestructura a sí mismo en una escala de la realidad, imperceptible para los sentidos humanos. A la par de esta cualidad, existen otras que codifican información. Ese es el caso del sistema neuronal espejo que codifica las intenciones de los demás, lo que permite entendernos. Los esquemas de aprendizaje se pueden estructurar, considerando el modelo holográfico de la mente, que expone la manera cómo la conciencia se distribuye por todo el sistema cerebral y funciona como un mecanismo de recuperación de información desde las diferentes áreas. Estos sistemas tienen como producto lo que en neurociencia se denomina memoria, la que es individual y colectiva. Finalmente, el lenguaje sustenta estas capacidades mentales y permite la manifestación comunicativa de los esquemas, a través de la interacción con los demás.
Estrategias Didácticas para mejorar el desempeño ortográfico en palabras de uso frecuente con c/s/z, a través del trabajo con textos expositivos y narrativos, en estudiantes de octavo grado del I.P.T Jeptha B. Duncan, Distrito de Panamá.
Authors: Hernández Maribel , Morales Ana Isabel 
Published: December 2019

El presente informe da cuenta de los resultados obtenidos en una investigación enfocada en bajar el nivel de errores ortográficos luego de observar en un pretest reiteradas faltas en sus escritos. Se implementó un seminario de ortografía en el que se trabajaron estrategias de lectoescritura y actividades de motivación. El estudio se aplicó a un grupo de 100 estudiantes de octavo grado en el distrito de Panamá. Los resultados generales muestran que en la escritura de palabras con c/s/z hubo una disminución de errores en un 13%. Se encontraron serias deficiencias en el manejo general de la ortografía.
Palabras clave: ortografía, textos expositivos, textos narrativos, faltas ortográficas, estrategias.
Keywords: spelling, expository texts, narrative texts, spelling mistakes, strategies.
Estudo de caso sobre os aspectos psicológicos após diagnóstico de sarcoma e realização de amputação
Authors: Leal Deborah Nóbrega da Silva , Rodicz Aline Mariana 
Published: December 2019

Os Sarcomas Sinoviais são tumores raros, marcados por sua agressividade e mau prognóstico. A principal forma de tratamento ainda é a ressecção cirúrgica do tumor primário, sendo a cirurgia de amputação uma dessas alternativas. Este procedimento pode acarretar em um grande impacto físico e emocional para o sujeito, não só pela perda do membro e de sua função, mas também pelos demais aspectos subjetivos que envolvem o próprio procedimento cirúrgico. Por isso faz-se importante a intervenção da psicologia ao paciente no pré, trans e pós cirúrgico, com o objetivo de minimizar suas ansiedades e angústias, possibilitando a expressão dos sentimentos e auxiliando na compreensão da situação vivenciada. Dessa forma,este estudo de caso vem ilustrar a intervenção psicológica à uma paciente durante todo seu processo de adoecimento (diagnóstico, tratamentos e cuidados paliativos) que, por sua vez, proporcionou redução no sofrimento emocional e melhora na qualidade de vida.
O ajustamento de crianças com doença crônica
Authors: Antão Joana , Portugal Gabriela , Silva Carlos 
Published: December 2019

Este trabalho procura averiguar o impacte das doenças crônicas no ajustamento psicológico das crianças, tendo em conta diferentes tipos de doenças, as suas características e a perceção dos pais acerca das mesmas.
A amostra é constituída por 176 crianças, dos 3 aos 10 anos, distribuídas por quatro grupos: crianças com asma, com cancro, com patologia uro-nefrológica e sem doença. A recolha de dados ocorreu nas salas de espera de dois hospitais portugueses.
Os instrumentos utilizados foram a Escala de Observação do Brincar (POS), itens do Revised Illness Perception Questionnaire (IPQ-R) e o Questionário de Capacidades e de Dificuldades (SDQ).
A análise dos resultados permitiu perceber que não existe uma relação linear entre o ajustamento psicológico e a presença de uma doença crónica e que a avaliação do ajustamento da criança através da observação direta do brincar nem sempre é coincidente com a perspetiva dos pais acerca desse ajustamento.
Living with a Severe Spinal Deformity: An Innovative and Personal Patient Account of Self-Management Using a Corset, Postural Correction, and Exercises
Authors: Gogala Andrej 
Published: December 2019

Conservative treatment of scoliosis using brace and exercises usually ends when growth stops. Scoliosis may, however, deteriorate in adulthood especially when curves are larger. The author decided to try to help himself when he was 43 years old. He had been diagnosed with juvenile idiopathic scoliosis when he was 7 years old, but his treatment with a Milwaukee brace ended when he was 11 years old. When his growth ended, the author had a severe scoliosis with a thoracic curve of around 100° Cobb. In adulthood, a corset from fabric with steel reinforcements was used for part of the day intermittently which also included days without wear. To derotate the rib cage, pressure to the rib hump was applied from behind. After some years it was obvious from photo documentation that some derotation had been achieved. The rib hump is smaller; ribs can now be seen on the concave side where they were not seen previously, and a skin mark which was located laterally before moved to the front side. Curves to the side as seen in anteroposterior X-ray images, however, did not improve. But the therapy proved helpful as marked cosmetic improvement was achieved and curve increase was most likely prevented.