bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and morphological spectrum of cutaneous metastases on cytology: A study of 225 cases
Authors: Kapatia Gargi , Sahu Saumya , Rohilla Manish , Gupta Parikshaa , Gupta Nalini , Srinivasan Radhika , Rajwanshi Arvind , Dey Pranab 
Published: October 2020

AbstractIntroductionAny type of cutaneous metastasis indicates dismal outcome of the disease. Skin is an unusual location for metastatic deposits from any tumour and has an incidence of about 0.8%‐5%. Fine needle aspiration cytology (FNAC) helps in the rapid diagnosis of metastasis with minimum pain.AimTo study the cytomorphological spectrum of cutaneous metastasis on FNAC.Material and methodsA total of 225 patients with diagnosis of cutaneous metastasis on cytology were analysed. May‐Grünwald Giemsa and haematoxylin‐eosin‐stained smears were studied and examined for the cytomorphological spectrum of cutaneous metastasis. Cell block was prepared in a few cases. In a subset of cases, immunohistochemistry was done to pinpoint the primary.ResultsAmongst the 225 patients studied, the mean age was 53.9 years. There was female preponderance with 125 females and 100 males. The commonest site was abdominal wall (n = 89) followed by chest wall (n = 60). The most common type of metastasising tumour was adenocarcinoma.ConclusionClinicians and pathologists must be aware of the clinico‐morphological spectrum of cutaneous metastasis for instant diagnosis followed by prompt management.
Comment on “Potential short‐term earthquake forecasting by farm animal monitoring” by Wikelski, Mueller, Scocco, Catorci, Desinov, Belyaev, Keim, Pohlmeier, Fechteler, and Mai
Authors: Zöller Gert , Hainzl Sebastian , Tilmann Frederik , Woith Heiko , Dahm Torsten 
Published: October 2020

AbstractBased on an analysis of continuous monitoring of farm animal behavior in the region of the 2016 M6.6 Norcia earthquake in Italy, Wikelski et al., 2020; (Ethology, 126(9), 2020, 931) conclude that animal activity can be anticipated with subsequent seismic activity and that this finding might help to design a “short‐term earthquake forecasting method.” We show that this result is based on an incomplete analysis and misleading interpretations. Applying state‐of‐the‐art methods of statistics, we demonstrate that the proposed anticipatory patterns cannot be distinguished from random patterns, and consequently, the observed anomalies in animal activity do not have any forecasting power.
Ultrasonographic examination of the tuber calcanei area: Technique and normal ultrasonographic images
Authors: Emond A.‐L. , Coudry V. , Seignour M. , Denoix J.‐M. 
Published: October 2020

SummaryUltrasonographic examination is an essential diagnostic tool that complements radiographic examination in the diagnostic work‐up of injury to the tuber calcanei area. Using a plantar approach, the superficial digital flexor tendon, gastrocnemius tendon, the bone surfaces of the two lobes of the tuber calcanei and the gastrocnemius bursa and the calcaneal bursa of the superficial digital flexor tendon (if distended) can be accurately assessed. Using a collateral approach, the tenocalcaneal ligaments of the superficial digital flexor tendon and the branches of the calcaneal tendon of the caudal femoral muscles can be imaged. This paper describes the normal anatomy of the tuber calcanei area and presents the complete ultrasonographic procedure and normal ultrasonographic images of this region.
Effects of supplements containing turmeric and devil’s claw on equine gastric ulcer scores and gastric juice pH
Authors: St. Blanc M. , Banse H. , Retif M. , Arana‐Valencia N. , Keowen M. L. , Garza F. , Liu C.‐C. , Gray L. F. , Andrews F. M. 
Published: October 2020

SummarySupplements containing turmeric (Curcuma longa) and devil’s claw (Harpagophytum species) are commonly fed to horses to decrease inflammation and pain, but because these supplements contain spices and plant irritants, warning labels such as 'these supplements might cause gastric irritation' are required. The purpose of this study was to determine whether supplements containing turmeric and devil’s claw cause or worsen gastric ulcers in stall‐confined horses, as suggested in required cautions that appear on the labels of these animal products. Twelve clinically healthy Thoroughbred horses with naturally occurring equine gastric ulcer syndrome (EGUS) scores >0 were included in a noncrossover study design. Horses were stratified by EGUS score and assigned to either the treatment (supplements containing turmeric and devil’s claw) or control (same supplements without active ingredients) group and fed the supplements for 28 days. Gastroscopy was performed on Days 0, 14 and 28. The EGUS score, nonglandular ulcer number (NGN) and severity (NGS) scores, and glandular number (GN) and severity (GS) scores were recorded during each gastroscopy by a masked investigator (F.M.A.). In addition, bodyweight, gastric juice pH, packed cell volume (PCV), total protein (TP) and blood biochemical results were measured on Day 0 and Day 28. Mean EGUS and NGS scores were significantly lower in both treatment and control groups by Days 14 and 28, when compared to Day 0. NGN score was not different among groups. Bodyweight, gastric juice pH and blood parameters did not change during the study. In conclusion, supplements containing turmeric and devil’s claw did not cause or worsen gastric ulcers or alter health parameters after 28 days of feeding.
Water stress and insect herbivory interactively reduce crop yield while the insect pollination benefit is conserved
Authors: Raderschall Chloé A. , Vico Giulia , Lundin Ola , Taylor Astrid R. , Bommarco Riccardo 
Published: October 2020

AbstractClimate change is predicted to hamper crop production due to precipitation deficits and warmer temperatures inducing both water stress and increasing herbivory due to more abundant insect pests. Consequently, crop yields will be impacted simultaneously by abiotic and biotic stressors. Extensive yield losses due to such climate change stressors might, however, be mitigated by ecosystem services such as insect pollination. We examined the single and combined effects of water stress, insect herbivory and insect pollination on faba bean yield components and above‐ and belowground plant biomass under realistic field conditions. We used rainout shelters to simulate a scenario in line with climate change projections, with adequate water supply at sowing followed by a long period without precipitation. This induced a gradually increasing water stress, culminating around crop flowering and yield formation. We found that gradually increasing water stress combined with insect herbivory by aphids interactively shaped yield in faba beans. Individually, aphid herbivory reduced yield by 79% and water stress reduced yield by 52%. However, the combined effect of water stress and aphid herbivory reduced yield less (84%) than the sum of the individual stressor effects. In contrast, insect pollination increased yield by 68% independently of water availability and insect herbivory. Our results suggest that yield losses can be greatly reduced when both water stress and insect herbivory are reduced simultaneously. In contrast, reducing only one stressor has negligible benefits on yield as long as the crop is suffering from the other stressor. We call for further exploration of interactions among ecosystem services and biotic and abiotic stressors that simulate realistic conditions under climate change.
Population variation in the thermal response to climate change reveals differing sensitivity in a benthic shark
Authors: Gervais Connor R. , Huveneers Charlie , Rummer Jodie L. , Brown Culum 
Published: October 2020

AbstractMany species with broad distributions are exposed to different thermal regimes which often select for varied phenotypes. This intraspecific variation is often overlooked but may be critical in dictating the vulnerability of different populations to environmental change. We reared Port Jackson shark (Heterodontus portusjacksoni) eggs from two thermally discrete populations (i.e. Jervis Bay and Adelaide) under each location's present‐day mean temperatures, predicted end‐of‐century temperatures and under reciprocal‐cross conditions to establish intraspecific thermal sensitivity. Rearing temperatures strongly influenced ṀO2Max and critical thermal limits, regardless of population, indicative of acclimation processes. However, there were significant population‐level effects, such that Jervis Bay sharks, regardless of rearing temperature, did not exhibit differences in ṀO2Rest, but under elevated temperatures exhibited reduced maximum swimming activity with step‐wise increases in temperature. In contrast, Adelaide sharks reared under elevated temperatures doubled their ṀO2Rest, relative to their present‐day temperature counterparts; however, maximum swimming activity was not influenced. With respect to reciprocal‐cross comparisons, few differences were detected between Jervis Bay and Adelaide sharks reared under ambient Jervis Bay temperatures. Similarly, juveniles (from both populations) reared under Adelaide conditions had similar thermal limits and swimming activity (maximum volitional velocity and distance) to each other, indicative of conserved acclimation capacity. However, under Adelaide temperatures, the ṀO2Rest of Jervis Bay sharks was greater than that of Adelaide sharks. This indicates that the energetics of cooler water population (Adelaide) is likely more thermally sensitive than that of the warmer population (Jervis Bay). While unique to elasmobranchs, these data provide further support that by treating species as static, homogeneous populations, we ignore the impacts of thermal history and intraspecific variation on thermal sensitivity. With climate change, intraspecific variation will manifest as populations move, demographics change or extirpations occur, starting with the most sensitive populations.
The psychopath in the corner office: A multigenre
Authors: Suskind Dorothy C. 
Published: October 2020

AbstractWorkplace bullies can be found in all organizations. Using a Narrative Inquiry and Arts‐Based Research methodological framework, this article shares the findings of a multiyear study in which 185 womens, in 27 states, and 15 countries share their stories of workplace abuse. Narrative Inquiry reflects the multilayered complexity of people’s lived lives by inviting research texts that utilize diverse genres and mediums to tell the story of the findings. Art‐Based Research invites the researcher to mine for meaning on a level not fully accessible through traditional narratives and then share out insights in genres that generate deep cognitive dissonance while evoking empathy and urging response. The stories, poems, book review, observational field notes, dialogues, lists, charts, and visual genres were crafted by the researcher as representations of the saturated themes that emerged from the data and are supported by other empirical research. This is a multigenre that tells the stories of successful psychopaths and the resilient women who survived them.
Dermatologic uses of bloodroot: a review and reappraisal
Authors: Fravor Lauren , Khachemoune Amor 
Published: October 2020

AbstractBloodroot (Sanguinaria canadensis) is a plant, native to North America, containing bioactive compounds that interrupt biological processes. It has been around for centuries and is known for its medicinal properties. Today, naturopathic remedies are becoming more and more popular, especially for skin ailments. There are an alarming number of online vendors marketing their bloodroot‐containing products as cures for skin cancer without any scientific evidence supporting such claims. Clinical data concerning the efficacy of bloodroot primarily come from case studies with unfavorable outcomes involving patients who self‐treated with bloodroot‐containing black salves. However, recent preclinical studies have concluded that sanguinarine, the active component of bloodroot, shows positive evidence of being an efficacious treatment for skin cancers at micromolar doses. This article reviews the mechanism of action of bloodroot as a skin cancer treatment, its misuse in clinical dermatology, and the FDA’s stance on products containing bloodroot that are marketed and sold to laypersons. Members of the public should be made aware of the dangers of self‐treating with bloodroot‐containing products through effective communication and education by clinicians.
Defining the target value of the coefficient of variation by continuous glucose monitoring in Chinese people with diabetes
Authors: Mo Yifei , Ma Xiaojing , Lu Jingyi , Shen Yun , Wang Yufei , Zhang Lei , Lu Wei , Zhu Wei , Bao Yuqian , Zhou Jian 
Published: October 2020

AbstractAims/IntroductionTo define the target value for the percentage coefficient of variation for glucose (%CV) as a measure of glycemic variability (GV) in Chinese diabetes patients.Materials and MethodsThis retrospective study included 3,007 diabetes patients who underwent continuous glucose monitoring for 3 days. Type 2 diabetes was divided into groups according to the received treatment: group 1, non‐insulinotropic agent (n = 138); group 2, insulinotropic agent (n = 761); group 3, basal insulin therapy (n = 100); group 4, premixed insulin (n = 784); and group 5, intensive insulin therapy (n = 612). Type 1 diabetes patients were included as group 6 (n = 612). %CV and percentage of time per day within, below (3.9mmol/L; TBR3.9) and above (10.0 mmol/L) the target glucose range (3.9–10.0 mmol/L) were computed. TBR3.9 ≥4% was defined as excessive hypoglycemia.ResultsType 2 diabetes with a premixed or intensive insulin regimen had an increased %CV compared with those receiving oral therapy or basal insulin. The upper limit of %CV in group 1 was 33%, which was adopted as the threshold to define excessive GV. For each treatment group, the percentage of people with TBR3.9 ≥4% was significantly greater in the subgroup with %CV >33% than ≤33% (P < 0.001). In participants who achieved TBR3.9 <4%, the time per day spent within the target glucose range of 3.9–10.0 mmol/L > 70% and time per day above 10.0 mmol/L <25%, the 95th percentile of %CV was 32.70%. Further receiver operating characteristic curve analysis showed that the cut‐off values of %CV for predicting TBR3.9 ≥4% varied by the type of diabetes and glycated hemoglobin categories.ConclusionsA %CV of 33% was set as the threshold for excess glucose variability in Chinese diabetes patients. Meanwhile, glycated hemoglobin and the type of diabetes should be considered for the goal‐setting of %CV.
Combination therapy of trichloroacetic acid, human autologous fibroblast injection and fibroblast seeded microfibrous collagen scaffold as a novel treatment for osteomyelitis diabetic foot ulcer
Authors: Nilforoushzadeh Mohammad Ali , Heidari‐Kharaji Maryam , Zare Mehrak , Zare Sona , Baiat Tork Batool , Jaffary Fariba 
Published: October 2020

AbstractA severe complication associated with diabetes is diabetic foot ulcer (DFU). Most patients with DFU require amputation. Although treatment of non‐healing diabetic ulcers is challenging, the use of novel therapies can be effective. In this report, we present the case of a woman with type 2 diabetes with DFU‐related osteomyelitis, who was treated with a combination therapy of trichloroacetic acid, calcium alginate and foam dressings, human autologous fibroblast injection, and a fibroblast cell‐seeded collagen scaffold. The results showed the positive effects of combination therapy on DFU. In the initial treatment, the wound area was measured to be 14 × 7 cm2, with a depth of 4 cm. After 6 months, the wound was measured to be 1.5 cm2, showing a 90% reduction of the wound area. Overall, this combination therapy was highly effective in the treatment of DFU‐related osteomyelitis, and could markedly prevent amputation among DFU patients.
Detection of scale drop disease virus from non‐destructive samples and ectoparasites of Asian sea bass, Lates calcarifer
Authors: Charoenwai Onanong , Senapin Saengchan , Dong Ha Thanh , Sonthi Molruedee 
Published: October 2020

AbstractNon‐destructive sampling methods offer practical advantages to detection and monitoring of viral pathogens in economically important farmed fish and broodstock. Here, we investigated whether blood, mucus and fin can be used as non‐lethal sample sources for detection of scale drop disease virus (SDDV) in farmed Asian sea bass, Lates calcarifer. Detection of SDDV was performed in parallel from three non‐destructive and seven destructive sample types, collected from both clinically sick fish and subclinical fish obtained from an affected farm. The results showed that SDDV was detectable in all 10 sample types with the percentage ranging from 20% to 100%. Blood was the best non‐destructive sample source exhibited by the fact that it yielded 100% SDDV‐positive tests from both sick (n = 12, 95% CI: 69.9–99.2) and clinically healthy fish (n = 4, 95% CI: 39.6%–97.4%) and is considered a “sterile” sample. This study also revealed concurrent infection of SDDV and two ectoparasites Lernanthropus sp. and Diplectanum sp., in all affected fish (n = 8, 95% CI: 46.7–99.3) during the disease outbreak. These ectoparasites also tested positive for SDDV by PCR, indicating that they were potential sample sources for PCR‐based detection of SDDV and possibly other viruses infecting Asian sea bass.
Palmer's test usefulness in the correct positioning of the Veress needle and the reduction of complications during laparoscopic access maneuvers
Authors: Brenner‐Anidjar Rony D , Rojo‐Novo Sara , Frías‐Sánchez Zoraida , Montaño‐Serrano María , Pantoja‐Rosso Francisco J , Terracina Dan , Pantoja‐Garrido Manuel 
Published: October 2020

AbstractAimAbdominal cavity access accounts for 50% of complications during laparoscopic surgery. Different safety maneuvers have been used to try to diminish these. Our study aims to establish the usefulness of Palmer's test in the correct positioning of the Veress needle and the reduction of complications during laparoscopic access maneuvers, when used in addition to the determination of intraabdominal pressure.MethodsProspective observational analytic multi‐centered cohort study with 370 patients undergoing gynecologic laparoscopy between July 2014 and November 2019, comparing the additional use of Palmer's test in 185 patients (Palmer‐Test‐Yes, PTY), with intraabdominal pressure determination alone in 185 patients (Palmer‐Test‐No, PTN).ResultsIntergroup homogeneity was described for the basic characteristics of both population samples, except for mean age and percentage of previous laparotomy. A total of 19 complications were recorded, 10 in PTY and 9 in PTN, with no significant differences (P = 0.814). No differences were found in the analysis of these complications, except for the rate of conversion to laparotomy, which occurred four times in the PTY group and none in PTN (P = 0.044). Furthermore, no differences were found once fixed for the history of previous laparotomy (P = 514.), nor for the percentage of successful access after the first attempt between both groups (P = 0.753).ConclusionPalmer's test, when used in addition to intraabdominal pressure determination, has not shown to be effective in preventing failed access to abdominal cavity or reducing complications associated with access maneuvers with the Veress needle. Hence, its systematic use is not justified, since it could generate a sense of false security.
Beyond direct contact: The theoretical and societal relevance of indirect contact for improving intergroup relations
Authors: White Fiona A. , Borinca Islam , Vezzali Loris , Reynolds Katherine J. , Blomster Lyshol Johanna K. , Verrelli Stefano , Falomir‐Pichastor Juan M. 
Published: October 2020

AbstractToday, physical and psychological barriers can reduce opportunities for the type of direct face‐to‐face intergroup contact first identified by Gordon Allport. Consequently, social psychological researchers have identified, developed and tested a burgeoning array of different forms of indirect contact, including, extended contact, Electronic‐ or E‐contact, imagined contact, vicarious contact and parasocial contact. In addition to providing a critical review of each of these forms, we argue that indirect contact is more than just a simple “replacement” for direct contact, but instead has the potential to improve intergroup relations for both minority and majority members in its own right. Relatedly, we acknowledge that indirect contact occurs within specific normative contexts embodied in legislation, institutions, and media and political contents. In fact, we recognize that indirect contact requires an integrative understanding of the role of intergroup norms and affective processes in order to effectively achieve public policy objectives to optimize effects on prejudice reduction.
Time is on the side of change in dentistry
Authors: Cothron Annaliese , McLeod Caroline 
Published: October 2020

AbstractThe 2020 environment challenges health professionals and stakeholders to reconsider oral health‐care design and business operations to drive meaningful change toward improving the oral health of all. The Three Domain Framework reinforces connections between social and structural determinants of health while promoting new opportunities to demonstrate value‐based solutions that connect care providers, individuals, and communities.
Profile of fatty acid lipid fractions of omega‐3 fatty acid‐enriched table eggs
Authors: Corrales‐Retana Leonor , Ciucci Francesca , Conte Giuseppe , Casarosa Laura , Mele Marcello , Serra Andrea 
Published: October 2020

AbstractThe omega‐3 fatty acid (FA) enrichment of yolk is a key means one of the main objectives to improve the nutraceutical properties of eggs. We evaluated the effect of the dietary inclusion of extruded linseed fed to laying hens on the fatty acid composition of the polar and non‐polar lipid classes of the eggs. Two groups of 36 Lohmann White Leghorn layers (65 weeks old) were each fed one of two different diets for a period of 12 weeks. The two diets consisted of a conventional cereal‐based diet concentrate (C) and a diet concentrate containing 5% linseed (L). The inclusion of linseed in the diet increased the content of α‐linolenic (C18:3n‐3), eicosapentaenoic (C20:5n‐3) and docosahexaenoic (C22:6n‐3) acids in neutral lipids, while a concomitant decrease in arachidonic acid (C20:4n‐6) was observed. As regards the polar fraction, the fatty acid composition was slightly affected by the dietary treatments except for C18:0 (+1.14 fold), C18:2n‐6 (+1.23 fold), C18:3n‐3 (+2.8 fold) and C22:6n‐3 (+1.41 fold). Principal component analysis demonstrated that very long‐chain FAs were more representative of polar lipids, except for C20:5n‐3, while neutral lipids were characterized by dietary n‐3 FA (C18:3n‐3).
Georgia Rural Hospital Tax Credit: Perspectives of Rural Health Executives
Authors: Opoku Samuel T. , Apenteng Bettye A. , Owens Charles , Kimsey Linda , Peden Angie , Ekpo Imaobong , Mase William A. , Akowuah Emmanuel 
Published: October 2020

AbstractPurposeIn 2016, Georgia implemented a rural hospital tax credit program through a legislative mandate that allows individuals and corporations to donate to qualifying rural hospitals in exchange for state income tax credit. The study examines the importance, success, and challenges of the program, and opportunities for improvement, from the perspective of Georgia rural hospital executives.MethodsThe study was a qualitative study using data from key informant telephone interviews with 21 hospital executives and administrators of eligible rural hospitals.FindingsHospital executives described the program as a valuable lifeline for struggling rural hospitals and an instrument for community engagement. They provided recommendations for legislative and programmatic modifications to ensure stability, transparency, and accountability.ConclusionResults highlight the popularity of the program among rural hospital leaders, but they also identify potential areas for improvement. The findings of the study can inform policy‐making efforts targeted at improving the nation's rural health infrastructure.