bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demographic Factors Associated with Insertional and Noninsertional Achilles Tendinopathy
Authors: Levitsky Matt , Greisberg Justin , Vosseller J Turner , Dey Shirin , Hickey Briana 
Published: October 2019

Category: Sports Introduction/Purpose: Achilles tendinopathy is a common clinical entity encountered by orthopaedic surgeons, although the demographics of patients that suffer from this pathology are incompletely understood. It has been suggested that there may be differences in patients that get insertional (IAT) and noninsertional Achilles tendinopathy (NIAT), and our clinical experience has been that older, less active patients tend to get insertional tendinopathy. The goal of this study is to further investigate the features of patients in a single institution who presented with Achilles tendinopathy. Methods: We used ICD-9 and ICD-10 codes to find patients who presented with Achilles tendinopathy to two foot and ankle surgeons at one academic medical center from 2007-2018. We made note of patient characteristics such as age, gender, BMI, medical comorbidities, and level of activity. Physical examination, including the presence of a gastrocnemius equinus, was noted as well. Characteristics of insertional and non-insertional tendinopathy subgroups were compared using Student’s T-tests and chi- squared tests. Results: The characteristics of 948 consecutive patients were analyzed. The mean age was 55 years and 50.5% of the patients were male. Patients with IAT had significantly higher BMIs than did those with NIAT (30.5 compared to 28.0, p < .05). The mean age was 54.5 years in the IAT group compared to 55.8 years in the NIAT group (p>.05). Patients with NIAT self-identified as active a greater percentage of the time (63% vs 45%, p<0.5). 76% of the IAT group had a gastrocnemius equinus on physical examination, compared to 67% of the non-insertional group. Antecedent fluoroquinolone antibiotic use was only reported in 10% of patients, and all of these patients presented with NIAT. Conclusion: The age at which patients present with insertional and noninsertional Achilles tendinopathy is not significantly different, although patients with NIAT had a lower BMI and self-identified as active a greater percentage of the time. A gastrocnemius equinus was present in a high percentage of patients with both IAT and NIAT. Fluoroquinolone use was not involved in most cases, although, when it was, patients presented with NIAT.
Adverse Events in Total Ankle Arthroplasty, Analysis of the FDA Medical and User Facility Device Experience Database
Authors: Mahmoud Karim , Metikala Sreenivasulu , O’Connor Kathryn , Farber Daniel 
Published: October 2019

Category: Ankle Arthritis Introduction/Purpose: Total ankle replacement has become a popular treatment option for end stage ankle arthritis. Most of the reports of adverse events following total ankle replacement have been from high volume institutions and are subject to either observational or selection bias as well as potential under-reporting as they do not include the experience of community and lower volume centers and surgeons. The FDA’s Medical and User Facility Device Experience (MAUDE) Database provides a more complete scope of adverse events due to the mandatory reporting requirements by the FDA of implant manufactures. We reviewed the database to identify the common modes of failure and complications of total ankle implants Methods: We retrospectively reviewed reports of the MAUDE database from November 2011 to September 2018 regarding all total ankle implants. Each device in the MAUDE database is classified with a 3-letter code, we identified the 2 codes assigned to total ankle arthroplasty devices, and manually searched the FDA’s published Device Classification list for adverse events. All events were reviewed and classified. Data related to patient age or sex, surgeon, medical center location are not available in the database Results: We identified 1000 adverse reports in the period between November 2011 and September 2018. After exclusion of duplicate reports for single events or reports irrelevant to total ankle arthroplasty, a total of 697 adverse event reports were noted. The most common mode of failure was aseptic loosening (21%), followed by infection (16%), alignment and mechanical issues (instability, malalignment, malposition, stiffness, impingement) (15%), implantation issues (pin, screw or drill breakage, alignment guide problems) (9%), polyethylene related problems (wear, displaced or fractured implants) (7%), bony and soft tissue overgrowth (6%), and peri-prosthetic fractures (5%). Conclusion: Our analysis reveals that the most reported mode of failure was aseptic loosening followed by infection. However, it is notable that there are a significant number of issues with implant alignment and mechanics, complications during implantation and polyethylene component failure that are under-reported in the literature. Knowledge of these adverse events may help surgeons avoid similar complications as well as lead to improvement in component implantation and design
Gastrocnemius Muscle Structure Remodels Within the First Month Following Acute Achilles Tendon Rupture
Authors: O’Connor Kathryn M , Hullfish Todd J. , Baxter Josh R. 
Published: October 2019

Category: Sports, Trauma, Achilles Tendon Introduction/Purpose: Two out of three patients Achilles tendon ruptures have limited plantarflexor function 1-year following Achilles tendon rupture. While tendon elongation has been reported as a possible mechanism of functional deficits, the effects of rupture on plantarflexor muscle structure has not been as rigorously investigated. A recent study found that gastrocnemius fascicle length was decreased 6-months following Achilles tendon rupture compared to the uninjured limb. However, the changes in muscle structure following the first month of injury – when the healing tendon is most susceptible to elongation – has not yet been established. The purpose of this study was to quantify the structural changes to the medial gastrocnemius in patients who suffered acute Achilles tendon ruptures and were treated non-operatively. Methods: To test our hypothesis that plantarflexor structure would undergo rapid remodeling following Achilles tendon rupture, we quantified muscle structure in ten patients (9 male, Age: 44 ± 12; BMI: 28.6 ± 6.5) who provide informed written consent in this IRB approved study. We acquired B-mode ultrasound images of the medial gastrocnemius muscle at the initial presentation (week 0), two weeks, and four weeks following the injury. The same investigator acquired all the ultrasound images and measured fascicle length, pennation angle, muscle thickness, and echo intensity. These measurements had a coefficient of variation less than 10%. We compared these structural measurements of the injured muscle at each time point with the contralateral muscle scans at the initial presentation using paired t-tests. Results: Gastrocnemius muscle structure following an acute Achilles tendon rupture differed with the healthy-contralateral muscle throughout the first four weeks following injury (Figure). Fascicle length was 15% shorter (P < 0.001) and pennation angle was 21% greater (P < 0.001) at the presentation of injury (week 0). These differences in fascicle length (P < 0.001) and pennation angle persisted throughout the 4 weeks after the injury (P < 0.008). Muscle thickness changes were not detected at any of the post-injury visits. Muscle quality, measured as mean echo intensity, was 8% lower in the injured limb immediately (P= 0.008) and 11% lower 2 weeks following injury (P < 0.001). At week 4 muscle quality had returned to within 1% of the contralateral limb (P = 0.393). Conclusion: Our findings support our hypothesis that the gastrocnemius muscle fascicles of the affected side would demonstrate shorter length and greater pennation angle than the contralateral control muscle. These findings are a preliminary set of data from a larger clinical cohort of patients that were enrolled in an ongoing 1-year long prospective study. Achilles tendon ruptures elicit rapid changes in the configuration and quality of the medial gastrocnemius, which may explain long-term functional deficits.
Rising Burden of Alcohol-Associated Foot and Ankle Fractures Presenting to U.S. Emergency Departments: 2000-2017
Authors: Pirruccio Kevin , Farber Daniel C. 
Published: October 2019

Category: Ankle, Trauma, Epidemiology Introduction/Purpose: The most frequent cause of traumatic foot and ankle fractures is a fall to the ground. Alcohol consumption, especially in excess, has the potential to impart a significant fall risk on patients by reducing postural control resulting in imbalance. However, the relationship between the consumption of alcohol and the risk of traumatic foot and ankle fracture is poorly characterized. The purpose of this study was to report national estimates, injury mechanisms, and demographic characteristics of patients presenting to U.S. emergency departments (EDs) with traumatic foot and ankle fractures associated with alcohol consumption. Methods: This cross-sectional, retrospective epidemiological study analyzes case narratives in the National Electronic Injury Surveillance System (NEISS) database to examine national estimates of traumatic foot and ankle fractures associated with alcohol consumption presenting to U.S. emergency departments between 2000 and 2017, sampling in two-year intervals. Data from the Organisation for Economic Co-operation and Development (OECD) on the “Value for Total U.S. Adult Alcohol Consumption in Liters/Capita” was used in a simple regression model to demonstrate how increased alcohol consumption in the United States has predicted changes in the national number of alcohol-associated foot and ankle fractures over time. Results: Nationally, alcohol-associated foot and ankle fractures increased significantly between the 2000-2001 (N=2,878; C.I. 1,869-3,887) and 2016-2017 (N=8,778; C.I. 6,751-10,806) periods (p<0.001). Simple regression (R2 = 0.87; p<0.001) demonstrated that in the U.S., a one-tenth increase in the total liters of alcohol consumed per capita predicted an additional 606 alcohol-associated foot and ankle fractures presenting to U.S. EDs. About two-thirds of patients suffered ankle fractures (65.6%; C.I. 61.1%-70.1%). Fractures were commonly sustained by male patients (58.4%; C.I. 53.9%-62.9%) at home (46.5%; C.I. 40.9%- 52.2%); roughly one-third of patients required admission to the hospital (29.7%; C.I. 24.5%-34.9%). The most common injury mechanisms for alcohol-associated foot and ankle fractures were falls to the ground from standing height (33.0%; C.I. 28.8%- 37.2%), and falls down stairs or steps (31.0%; C.I. 26.1%-35.9%). Conclusion: Falls to the ground mechanistically link alcohol consumption to traumatic fractures of the foot and ankle. These new findings highlight how the negative societal impacts of alcohol – and potentially other substances – may be overlooked. As a result, this information should serve as an impetus to direct national attention towards awareness and preventative measures. Furthermore, our findings may help clinicians identify, educate, and counsel patients with certain demographic risk factors for alcohol-associated foot and ankle fractures.
Clinical Significance of Ankle Arthroscopy in the Diagnosis of Type B Ankle Fracture Associated with the Distal Tibiofibular Syndesmosis Injury
Authors: Qiang Huang , Xiangyang Xu 
Published: October 2019

Category: Arthroscopy, Trauma Introduction/Purpose: To investigate clinical significance of ankle arthroscopy in the diagnosis of type B ankle fracture associated with the distal tibiofibular syndesmosis injury. Methods: From February 2014 to December 2016, the authors diagnosed and treated 35 cases of type B ankle fractures. including 23 males and 12 females; with an average age of (43.05±12.480) years. Each patient underwent preoperative assessment: according to the patient’s clinical manifestations and imaging examination, and before the operation and after internal fixation of ankle fracture, the Cotton test and the external rotation test were done in the C arm X-ray, the initial diagnosis whether there is the distal tibiofibular syndesmosis injury. When the Cotton test and the external rotation test was used, Ankle arthroscopy was used to observe and evaluate whether there is the distal tibiofibular syndesmosis injury. For patients with the distal tibiofibular syndesmosis injury, In addition to the internal fixation of the ankle fracture, the TightRope was used to repair the injury. And observation of repair effect by ankle arthroscopy. Results: After internal fixation of ankle fracture, the Cotton test and the external rotation test was performed under the C arm X-ray, there were no the distal tibiofibular syndesmosis injury in 22 patients. Preoperative CT showed 6 cases of combined the distal tibiofibular syndesmosis injury, Preoperative MRI showed 13 cases of combined the distal tibiofibular syndesmosis injury. Ankle arthroscopy confirmed 11 cases of combined the distal tibiofibular syndesmosis injury. The sensitivity of ankle arthroscopy and MRI diagnosis combined with the distal tibiofibular syndesmosis injury was higher than that of CT sensitivity(P<0.05). The sensitivity of ankle arthroscopy for the diagnosis of the distal tibiofibular syndesmosis injury was weaker than that of MRI in the diagnosis of the distal tibiofibular syndesmosis injury (P<0.05). MRI diagnosis of the distal tibiofibular syndesmosis injury can be false positive. Conclusion: Ankle arthroscopy can directly observe the medial triangle ligament of the ankle, the distal tibiofibular syndesmosis injury, which provides the basis for correct diagnosis and treatment of Type B ankle fracture with the distal tibiofibular syndesmosis injury. And it can evaluate the stability of ankle after repairing the distal tibiofibular syndesmosis injury.
Clinical Outcomes of Acute Achilles Tendon Rupture Repair Utilizing Supine Positioning
Authors: Rogero Ryan , Beck David , Larwa Joseph , Fuchs Daniel , Raikin Steven M. 
Published: October 2019

Category: Sports, Trauma Introduction/Purpose: With no consensus regarding the optimal technique for repair of Achilles tendon ruptures, identifying techniques which minimize complications and maximize functional outcomes is essential. Previous studies on Achilles repair performed in the supine position have demonstrated low complication rates, avoidance of issues related to anesthesia set-up of prone positioning, and decreased operating room times, though these studies have included relatively low patient numbers and lacked functional outcomes. The purpose of this study is to evaluate the clinical outcomes of a large cohort of patients undergoing acute Achilles tendon repair in the supine position. Methods: We conducted a retrospective review of patients undergoing open repair of acute Achilles tendon ruptures with supine positioning by one fellowship-trained foot & ankle surgeon at a single outpatient surgical location from 2010-2016. During each procedure, a longitudinal incision was made just medial to the tendon extending approximately 3.5 cm both proximally and distally from the level of the rupture. Exclusion criteria included age <18 years old, repair >21 days from date of injury, and undergoing any additional procedures other than concomitant tendon transfers. Postoperative chart notes were reviewed to identify any complications experienced by patients, and surgical site records were reviewed for tourniquet times. Patients were contacted and asked about their satisfaction with surgical outcome and to complete the Foot & Ankle Ability Measure (FAAM)- Activities of Daily Living (ADL) and –Sports subscales, as well as the Visual Analog Scale (VAS) for pain. Results: Two-hundred eleven patients, including 31 (14.7%) females, were included in the study, with a mean age of 40.9 years and mean BMI of 28.8 kg/m2. Patients had an average of duration from injury to surgery of 8.5 days (range, 1-21 days) and mean tourniquet time of 35.5 minutes (range, 16-77 minutes). Four patients (1.9%) experienced a postoperative complication, including 2 superficial wound infections and 2 deep vein thromboses. There were no sural nerve-related injuries or tendon re-ruptures. At an average of 56.8 months postoperatively (range 24-99 months), patients reported a mean VAS pain of 0.6 ± 1.3/10 and mean FAAM-ADL and FAAM-Sports scores of 93.9 ± 12.4/100 and 84.7 ± 19.6/100, respectively. Additionally, 91.4% reported being satisfied with the outcome of the surgery. Conclusion: With an extremely low complication rate, mid- to long-term functional scores comparable to other reported Achilles tendon repair techniques, and high rate of patient satisfaction, open repair of Achilles tendon ruptures performed in a supine position offers surgeons a safe and effective treatment method.
Clinical and Radiographic Outcomes of 3D Printed Total Talus Arthroplasty
Authors: Scott Daniel , Steele John , Fletcher Amanda , Parekh Selene 
Published: October 2019

Category: Ankle, Ankle Arthritis, Hindfoot, Trauma Introduction/Purpose: Patients with talar avascular necrosis have limited treatment options to manage their symptoms. Historically, surgical options have been limited and can leave patients with little ankle motion and have high failure rates. The use of custom 3D printed total talar replacements (TTR) has arisen as a treatment option for these patients, possibly allowing for better preservation of hind-foot motion. Patients undergoing TTR will demonstrate a statistically significant improvement in FAOS scores at one year after surgery. Methods: We retrospectively reviewed 15 patients who underwent a TTR over 2 years. Patient outcomes were reviewed including age, sex, comorbidities, etiology of talar pathology, number and type of prior surgeries, pre-operative and post-operative weight bearing radiographs, as well as FAOS and VAS scores, and range of motion. Data analysis performed with student T-test and multivariate regression. Results: Results: FAOS scores showed statistically significant improvements post-operatively as compared to pre-operative scores. There was a statistically significant decrease in VAS pain scores from 7.0 pre-operatively to 3.4 post operatively. There was no significant difference in pre-operative and post-operative coronal and sagittal alignment on weight bearing radiographs. All FAOS sub-score shows statistically significant improvements, with the exception of the sports/recreation sub-scale, did show a trend towards improved outcomes (p =0.19). Average follow-up was 12.8 months. Conclusion: Our hypothesis was confirmed that these patients show statistically significant improvements in AOFS and VAS scores at 1 year. Sagittal and coronal alignment was well maintained at an average of 1 year following surgery. TTR represents an exciting treatment options for patients with talar avascular necrosis, though longer-term follow-up is needed.
The Prevalence of Hallux Rigidus and its Risk Factors
Authors: Senga Yoshiyuki , Nishimura Akinobu , Sudo Akihiro 
Published: October 2019

Category: Midfoot/Forefoot Introduction/Purpose: Hallux rigidus (HR) is known as osteoarthritis of the first metatarsophalangeal joint (MPJ). The radiographical findings of HR are characterized by joint space narrowing, osteophytic lipping of the metatarsal head and proximal phalanx and sesamoid hypertrophy. HR is not so rare in daily medical practice, but its prevalence and risk factors are not completely understood. The purpose of this cross-sectional study, using a population-sample from Japan, is to investigate the prevalence of HR and its risk factors among Japanese community dwellers. Methods: In this study, we analyzed the cohort studies in 2009, 2011, 2013 and 2015 covering the elderly (=50 years). We excluded the participants with hallux valgus (HV) because it is difficult to distinguish HR from HV completely. Knee osteoarthritis (KOA) was scored according to the Kellgren-Lawrence grading system and was defined as grade=2. HR was scored according to the Hattrup and Johnson classification and was defined as grade=1. Continuous and categorical variables were compared using the t-test and chi-square test, respectively. The logistic regression model was used to examine the relationship between predictor variables and HR. The Cochran-Armitage trend test was used to examine the relationships between the presence or absence of HR and the severity of KOA in a linear trend. All p values presented are two-sided and p values < 0.05 were considered statistically significant. Results: A total of 416 (171 men, 245 women) participants fulfilled this study criterion. The prevalence of HR was 17.8%. The rate of grade0, grade1, grade2, and grade3 of HR were 82.2%, 10.1%, 6.7%, and 0.96%, respectively. Univariate analysis revealed age (=65), KOA, and Gout Attack (GA) were significantly associated with HR (Table 1). In addition, they were confirmed as independent risk factors of HR in the multivariate analysis. All parameters were significantly associated with HR. The odds ratio of age, KOA, and GA were 2.46, 1.83, and 4.87, respectively (p <0.05). KOA severity is significantly associated with the presence or absence of HR (p <0.05). Conclusion: While previous reports have demonstrated a higher prevalence of HR (27.2-44.4%), HV was not excluded in that study. To achieve the accurate evaluation, we examined the epidemiology and prevalence of HR among participants without HV. HR prevalence in the elderly (=50 years) was 17.8%. Although multifactorial risk factors have been proposed in the literature, our study revealed that age (=65), KOA, and GA were the independent risk factors for HR. KOA severity was associated with the presence or absence of HR.
Nosocomial spread of OXA-232-producing Klebsiella pneumoniae ST15 in a teaching hospital, Shanghai, China
Authors: Li Xin , Ma Wei , Qin Qin , Liu Shanrong , Ye Liyan , Yang Jiyong , Li Boan 
Published: October 2019

Abstract

Background
The spread and outbreak of Enterobacteriaceae producing OXA-48-like carbapenemases have become more and more prevalent in China.

Results
A total of 62 non-duplicated OXA-232-producing K. pneumoniae (OXA232Kp) were isolated between 2015 and 2017. An outbreak of OXA232Kp was observed in burn ICU. The 62 OXA232Kp isolates were all belongs to ST15 and categorized into two PFGE types (A and B). Type A was dominated of the isolates, which contained 61 clinical isolates and divided into 10 subtypes (A1-A10). In addition, most of OXA232Kp strains exhibited low-level carbapenems resistance. All strains carried a 6141 bp ColKP3 plasmid harboring the blaOXA-232 gene which is highly homologous to other blaOXA-232-bearing plasmids involved in other studies in eastern China.

Conclusions
In this study, clone transmission of OXA232Kp ST15was observed. Highly significant homology among the blaOXA-232-bearing plasmids indicated the important role of the 6.1 kb ColE-like plasmid on the prevalence of blaOXA-232 gene in China.