bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contacts parent-enfant en contexte de placement : liens entre la sensibilité du parent d’accueil et les réactions des enfants à la suite des contacts
Authors: Auger Lisa , Karine Poitras  , George M. Tarabulsy  
Published: August 2020

Cadre de la recherche :Au Québec, la Loi sur la protection de la jeunesse encourage le maintien des contacts entre les enfants placés en famille d’accueil et leurs parents biologiques. Or, il n’existe pas de consensus empirique quant aux conséquences de ces contacts sur les enfants placés.Objectifs :Notre étude vise à examiner les liens entre la sensibilité du parent d’accueil et les réactions des enfants à la suite de ces contacts, en considérant trois facteurs potentiellement confondants soit la sécurité d’attachement, l’âge au moment du premier placement et la fréquence des contacts.Méthodologie :Il s’agit d’une étude quantitative réalisée auprès de 51 enfants placés âgés de 12 à 45 mois. Une entrevue individuelle auprès du parent biologique nous permet de documenter la fréquence des contacts réalisés auprès de l’enfant. Les réactions de l’enfant, à la suite des contacts, sont rapportées par le parent d’accueil. La sensibilité parentale et la sécurité d’attachement sont observées lors d’une visite au domicile du parent d’accueil. Résultats :La plupart des enfants affichent au moins une réaction négative à la suite des contacts. Les réactions négatives rapportées sont associées significativement à l’insensibilité du parent d’accueil. Conclusions :Notre étude suggère que la sensibilité du parent d’accueil peut être un facteur favorable à de meilleures transitions à la suite des contacts.Contribution :Cet article contribue à la réflexion sur la tenue des contacts suivant une mesure de placement et sur les réactions manifestées par les enfants à la suite de ces contacts.
Agronomic Behavior of Six Saladette Tomato Hybrids Grown under Shade Mesh
Authors: Cortez María del Pilar Marín , Montejo Neymar Camposeco 
Published: August 2020

Aims: The objective was to evaluate six indeterminate saladette tomato hybrids in Southeast, Coahuila, Mexico. Under shade house covered with anti-aphid mesh, to determine their performance, commercial quality and adaptability.
Study Design: The experimental design used in each test was completely randomized model with six treatments and three repetitions each. The treatments were hybrids Lubino were Lubino F1, Zopilote F1, Sahariana F1, Raptor F1, Quetzal F1 and RTF-713172 F1.
Place and Duration of Study: The site was Parras Valley Tomatoes in Parras, Coahuila, México. During april to November 2017.
Methodology: The distance between the lines were 1.80 m, between the plantpots 36 cm and two plants per plantpots, with approximately 30,000 plants per hectare calculated. The genotypes used were Lubino F1, Zopilote F1, Sahariana F1, Raptor F1, Quetzal F1 and RTF-713172 F1. The following agronomic characteristics were evaluates: yield, total number of fruits, average fruit weight, number of fruits per bunch, length between clusters, length of internodes, main stem thickness and commercial quality of fruit.
Results: The results indicate that the highest yielding hybrid was Zopilote with 4.3 kg plant-1, followed by Saharan, the average weight of the product obtained best in Saharan and Quetzal with 122.33 and 118.33 g respectively, the most compact variety was Zopilote due to the shorter distance between bunches, contrary to what was demonstrated by Lubino.
Conclusion: The best variety for the Southeast of Coahuila is Zopilote F1, due to its higher yield and for being a compact plant.
Left Main and Right Coronary Artery Arising from Single Coronary Trunk: A Very Rare Cardiac Anomaly
Authors: Gupta Aditya , Rai Rohit , Shaikh Shakil , Munde Kalyan , Bansal Narendra O. 
Published: August 2020

Aim: Single coronary artery is a rare anomaly. Patients may present with syncope, angina or rarely sudden cardiac death.
Presentation of Case: Patient presented with dyspnea on exertion for one year. On 2D Echo patient had small restrictive VSD. On coronary angiography single coronary artery from right cusp was seen. On CT angiography anomalous origin was confirmed. There was no malignant course of coronary artery.
Discussion: Anomalous origin of coronary arteries are rare cardiac anomalies. It can present as syncope, angina, or sudden cardiac death especially in patients with malignant course of coronary artery passing between aorta and pulmonary artery. Hence CT coronary angiography is useful to rule out the malignant course. In our patient, there was no malignant course hence managed conservatively.
Conclusion: Anomalous origin of coronary artery is a rare anomaly and requires tailored treatment according to type and course of artery.
Maturation and Fecundity of Large Freshwater Prawn Macrobrachium malcolmsonii and Macrobrachium gangeticum in the Ganga River System in India
Authors: Prasad Suday 
Published: August 2020

The Ganga is the largest perennial river in India. The prawns’ fishery resources are declining in middle stretch of the river Ganga near Patna. The present paper deals with the maturation and fecundity of large size Macrobrachium species like Macrobrachium gangeticum (Bate) and Macrobrachium malcolmsonii (Edwards) were estimated for the period of two years. Maturity and fecundity of prawn were evaluated according to the size of prawn, ovary and breeding frequency. The initial stage developing ovaries of M. gangeticum were observed small & light yellowish green colour but at stage II to mature gonad of M. gangeticum were found deep yellow green mass in the carapace, whereas in M. malcolmsonii the developing stage of ovaries was observed large yellowish in colour and matured female gonad were found comparatively in large and deep yellow in the carapace. The gravid females observed long setae at the base of genital aperture and 1- 4 pleopodes in both species. After mating, eggs were transferred by both the female prawn from ovary to brood pouch. Berried prawn M. gangeticum one week old fertilized eggs were looked as yellowish green finally brawn color. Whereas, in M. malcolmsonii, one week fertilized eggs were looked as yellowish-grey then finally changed deep gray. M. gangeticum and M. malcolmsonii female releases of eggs, her ovaries displayed either stage resting or zero characteristics. The species of M. gangeticum possess minimum of 8000 eggs with size 75 mm and the maximum 76,240 eggs with respective size 190 mm, whereas M. malcolmsonii the minimum fecundity observed 8100 eggs with size 75 mm and the maximum fecundity was 81,200 eggs of 190 mm size. The total weights of the eggs per female prawn as well as the mean number of eggs were improved with cumulative length and weight. The breeding frequency of both species were found four times and in first breeding the number of eggs was found slight, but it increased comparatively in second and third breeding and got decreased again in fourth breeding.
Assessment of Chemoprotective Potential of Curcumin against DMBA-Croton Oil Induced Skin Cancer in Mice
Authors: Sharma Sarita , Koneri Raju , Sharma Gaurav Kumar , Chandrul Kaushal K. 
Published: August 2020

Background: Skin cancer is the most aggressive form of cancer with a high mortality rate. Different medications of skin cancer are accessible, yet because of improvement of multi-drug resistance, flow and rising chemotherapies have a generally low achievement rate. This emphasize the importance of discovering new compounds that are both safe and effective against skin cancer. This study used and compared different routes of administration of a natural compound curcumin to investigate the anti-cancer effect.
In this investigation it has been resolved that the curcumin expands CAT and SOD levels alongside decline in the TBARS levels.
Methods: The hindrance of tumour rate Curcumin was assessed in mice on two phase procedure of skin carcinogenesis incited by single utilization of DMBA/7,12-Dimethylbenz[a]-anthracene (100 µg/100 µl of CH3)2CO), and after 2 weeks advanced by rehashed use of croton oil (1% CH3)2CO/thrice in seven days) till the finish of the trial (i.e. 16 weeks). Oral administration of drug at a dose of 500 mg/kg body weight/day at the pre-initiation stage (i.e. 7 days prior and 7 days after DMBA application), promotional stage (for example from the time of croton oil application) and at both the stages (i.e. 7 days before DMBA application and proceeded till the finish of investigation) to the mice Treatment were started 1 week before the exposure to the carcinogen and continued till 25 weeks daily. At the end of experimental period all the animals were sacrificed and observed for various parameters.
Results: The following parameters (body weight, biochemical studies, haematological studies) were observed and data was collected time to time and calculated statistically to evaluate the anticancer effect of curcumin was found to effective against the skin cancer.
Susceptibility Pattern of Different Parts of Moringa oleifera against Some Pathogenic Fungi, Isolated from Sputum Samples of HIV Positive Individuals Co-Infected with Pulmonary Tuberculosis
Authors: Onuoha Vivian C. , Enweani Ifeoma B. , Okereke Ogbonnia Ekuma- 
Published: August 2020

Background: Opportunistic fungal infection in HIV positive individualshas a high risk of morbidity and mortality as it could be a pointer to systemic infection. Moringa oleifera is one of the 14 species of the family Moringaceae with traditional effectiveness in anti–helminthic, analgesic, anti-ulcerative, anti-microbial, etc.
Aim: This study was designed to determine the susceptibility pattern of different parts of Moringa oleifera against some pathogenic fungi using dried Morringa oleifera seed, bark, pod, and leaf extracts/fractions as agents.
Materials and Methods: A total of 132 subjects (62 males and 70 females) attending outpatient clinics (OPD) at Nnamdi Azikiwe University Teaching Hospital Nnewi, and Holy Rossary Hospital Emekuku Owerri, Nigeria were recruited for this study. The HIV status of the test subjects was confirmed using immuno-chromatographic technique and their sputum screened for Tuberculosis (TB) using Ziehl Nelsen staining technique. The sputum samples were also cultured on Sabouaurd dextrose agar with and without chloramphenicol incubated at 25oC with examination of growth every 3 days for two weeks. Identification of isolates was done using Gram staining methods, chromogenic media and slide culture.700g, 220g, 500g, and 250g each of the different parts of the pulverized Moringa oleifera (seeds, barks, pods, and leaves) were weighed and exctracted using Soxhlet extractor and methanol as solvent.
Results: The prevalence of fungi isolates from test subjects shows that Candida albicans has the highest frequency of 25(26.6%), with the least prevalent being Aspergillus flavus and Phialemonium curvatum at 2(2.1%) respectively. There was also a positive significant correlation between TB and fungi infection in HIV-sero positive subjects (P<0.05).The invitro antifungal activity of these Moringa oleifera extracts/fractions against the test isolates showed no antifungal activity except for ethyl acetate fraction which demonstrated the most prominent activity against A. fumigatus with zones of inhibition of 3-10mm diameter with the least activity against C. krusei with zones of inhibition of 3-6mm diameter. However, the antifungal activities of fluconazole which served as a control in the antifungal susceptibility against the test isolates were more effective than the extract/fractions against the test isolates with a minimum inhibition concentration (MIC) of 50-200mg/ml against 25-100mg/ml for ethylacetate fraction.
Conclusion: The comparable antifungi effect of ethylacetate fraction of M. oleifera leaf with that of fluconazole, suggests that ethylacetate fraction of M. oleifera leaf could aid the treatment of pathogenic fungi due to its potential applications in Pharmaceutical industry, thereby ameliorating the morbidity and mortality rate of HIV positive co-infected TB subjects.
Fungal Infections in Plateau State, Nigeria
Authors: Enurah L. U. , Shaibu S. J. , Bitrus A. A. , Zekeri A. H. Momoh- , Lombin L. H. , Barde I. J. 
Published: August 2020

This paper describes a study carried out on people of different ages with various skin diseases who submitted themselves for examination and diagnoses at the Dermatophylosis Research Centre of the National Veterinary Research Institute, Vom, Plateau State, Nigeria. Samples of skin scrapping were collected and cultured on Sabouraud Dextrose Agar (SDA) while some were examined under the microscope for possible morphological identification of the fungi. The results showed that out of the thirty samples analyzed, nine genera of fungi were isolated comprising of Trichophyton 10 (33.3%), Aspergillus 9 (30%), Penicillum 4 (13.32%), Microsporum 2 (6.70%), Epidermorphyton 1 (3.33%), Trichosporum 1 (3.33%), Cryptococcus 1 (3.33%), Mucor 1 (3.33%), and Cephalosporium 1 (3.33).
The study revealed high incidence of human fungal diseases, a situation that calls for good hygiene practices in the study area to mitigate and possibly eradicate the prevalence of human skin diseases in the rural area of Plateau State.
Labor scheduling using NPV estimates of the marginal benefit of additional labor capacity
Authors: Thompson Garry M. 
Published: July 2002

AbstractAn extensive literature exists on the problems of daily (shift) and weekly (tour) labor scheduling. In representing requirements for employees in these problems, researchers have used formulations based either on the model of Dantzig (1954) or on the model of Keith (1979). We show that both formulations have weakness in environments where management knows, or can attempt to identify, how different levels of customer servve affect profits. These weaknesses results in lower‐than‐necessary profits.This paper presents a New Formulation of the daily and weekly Labor Scheduling Problems (NFLSP) designed to overcome the limitations of earlier models. NFLSP incorporates information on how changing the number of employees working in each planning period affects profits. NFLP uses this information during the development of the schedule to identify the number of employees who, ideally, should be working in each period. In an extensive simulation of 1,152 service environments, NFLSP outperformed the formulations of Dantzig (1954) and Keith (1979) at a level of significance of 0.001. Assuming year‐round operations and an hourly wage, including benefits, of $6.00, NFLSP's schedules were $96,046 (2.2%) and $24,648 (0.6%) more profitable, on average, than schedules developed using the formulations of Danzig (1954) and Keith (1979), respectively. Although the average percentage gain over Keith's model was fairly small, it could be much larger in some real cases with different parameters. In 73 and 100 percent of the cases wa simulated NFLSP yielded a higheprofit than the models of Keith (1979) and Danzig (1954), respectively.
Early postnatal appearance of enhanced noradrenaline content in the brain of vasopressin‐deficient brattleboro rat; normal adrenoceptor densities and aberrant influences of vasopressin treatment
Authors: Boer G.J. , Feenstra M.G.P. , Botterblom M.J.A. , Korse V. , Te Riele P. 
Published: July 2002

AbstractThe course of postnatal development of noradrenaline (NA) and its unconjugated free metabolite 3‐methoxy‐4‐hydroxyphenylglycol (MHPG), as well as the influence on early chronic vasopressin treatment, were investigated in various brain regions of the hereditary vasopressin‐deficient (homozygous di/di) Brattleboro rat. In addition, the densities of the adrenergic receptor subtypes were measured in adult brain.Brain NA levels of di/di pups appeared enhanced already at 7 days of age when compared with data of heterozygous (+/di) controls. This was also seen in areas not known to receive a vasopressinergic input, e.g. the frontal cortex. Levels of MHPG also differed between genotypes, but changes were slight and either a decrease or increase, depending on age and region tested. Saturation analyses of α1‐, α2‐, and β‐adrenoceptor binding on crude membrane preparations of some brain regions revealed no differences in adulthood.Chronic treatment with vasopressin between 6 and 13 days of age reduced the enhanced NA brain levels throughout the brain of the di/di Brattleboro pups. The known vasopressin‐mediated enhancement of NA turnover in adult brain was also measurable in +/di pups of this neonatal period (MHPG/NA ratios), indicating the early maturation of the interaction of vasopressinergic and NAergic systems. However, the dose‐response in the di/di Brattleboro rat was biphasic with a decrease at a low dose of vasopressin.Since changes were found throughout the brain, it was concluded that vasopressin deficiency had altered the maturation of NA neurons of the locus coeruleus which may be due to the absence of a presumed inhibitory control of vasopressin on synthesis and storage mechanisms at the perikaryal level.
Brain large neutral amino acids and catecholamines in parenterally nourished preterm rabbits
Authors: Lopez Suzanne M. , Rassin David K. 
Published: July 2002

AbstractTotal parenteral nutrition (TPN) has been adapted as a standard for providing nutrition to ill term and preterm infants. The availability of tyrosine in amino acid preparations utilized for TPN is limited and may potentiate a tyrosine‐deficient state. Phenlyalanine hydroxylase activity, responsible for catalyzing tyrosine synthesis, has been suggested to be decreased in fetal and neonatal animals. Parenterally nourished premature rabbits (n=16) and suckled rabbits (n=19) were studied in order to compare growth parameters and amino acids in the plasma and brain, as well as whole brain catecholamine concentrations. Influx velocities into the brain of amino acids were also determined in these two groups.The preterm rabbit's average birth weight (42.6±6.0) was less than that of term rabbits (56.7±8.7, P<0.005). Significantly lower concentrations of the catecholamine precursor tyrosine were found in both the plasma and brain of the parenterally nourished animals compared to the suckled animals. Tyrosine is reduced in the brain in TPN‐supported animals reflecting both low tyrosine intake and increased plasma concentrations of large neutral amino acids that compete for uptake at the blood‐brain barrier. However, no difference was observed between the two groups in their brain catecholamine concentrations.The seven‐day parenterally nourished rabbit appears to be tyrosine‐deficient but no evident effects on brain catecholamine concentrations were seen. The effects and impact of a tyrosine‐deficient state might better be evaluated by regional evaluation of catecholaminergic areas of the brain or over a longer period of parenteral nutrition.
TYROSINE PHOSPHORYLATION INDUCED BY INTEGRIN‐MEDIATED ADHESION OF RETINAL NEURONS TO LAMININ
Authors: Malosio Maria Luisa , Curtis Ivan De 
Published: July 2002

AbstractIntegrin α6β1 is a laminin receptor involved in adhesion and neurite extension of retinal neurons on laminin. The present study was carried out to understand some of the intracellular mechanisms which allow integrin‐mediated neurite extension on laminin in primary neuronal cultures. Both integrin‐mediated adhesion to laminin and antibody‐induced integrin clustering resulted in the increased tyrosine phosphorylation of a 120 kDa polypeptide which was identified as the focal adhesion kinase. The kinetics of phosphorylation and dephopsphorylation of this kinase were dramatically different in neurons plated on laminin, than in neurons in which the receptors were clustered with anti‐integrin antibodies. To look at possible interactions of the focal adhesion kinase with integrins, we made use of sucrose velocity gradients, which have allowed the identification of a large complex containing the α6β1 laminin receptor. Analysis of the gradients showed that the focal adhesion kinase was not associated with the integrin receptors under these experimental conditions, while about 26% of the c‐Src kinase codistributed with the integrin receptor complex, and showed a molecular size and a distribution similar to that of a 59 kDa phosphoprotein co‐migrating with the α6β1 receptor. Our results suggest that integrin‐induced tyrosine phosphorylation is an early intracellular event during neuronal adhesion, and that the integrin‐mediated increase in tyrosine phosphorylation of the focal adhesion kinase is not sufficient per se for the induction of neurite outgrowth. Furthermore, our data indicate that Src kinase may be involved in integrin‐mediated neuronal interactions with laminin.
Osteoprotegerin ameliorates sciatic nerve crush induced bone loss
Authors: Bateman Ted A. , Dunstan Colin R. , Lacey David L. , Ferguson Virginia L. , Ayers Reed A. , Simske Steven J. 
Published: July 2002

AbstractThis study examines the ability of osteoprotegerin (OPG) to prevent the local bone resorption caused by sciatic nerve damage. Sixty‐five 18‐week‐old male mice were assigned to one of six groups (n = 10–11/group). A baseline control group was sacrificed on day zero of the 10‐day study. The remaining groups were placebo sham operated, placebo nerve crush (Plac NC) operated, 0.1 mg/kg/day OPG + nerve crush (LOW), 0.3 mg/kg/day OPG + nerve crush (MED), and 1.0 mg/kg/day OPG + nerve crush (HI). Nerve crush or sham operations were performed on the right leg. The left leg served as a contralateral control to the nerve crushed (ipsilateral) leg. The difference in mass between the right and left femur and tibia was examined. Additionally, quantitative histomorphometry was performed on the right and left femur and tibia diaphyses. Nerve crush resulted in a significant loss of bone mass in the ipsilateral side compared to the contralateral side. Bone mass for the ipsilateral bones of the Plac NC group were significantly reduced by 3.8% in the femur and 3.5% in the tibia compared to the contralateral limb. The percent diminution was reduced for OPG treated mice compared to the Plac NC group for both the femur and tibia. In the femur, the percent reduction of ipsilateral bone mass was reduced to 1.0% (LOW), 1.3% (MED) and 1.6% (HI) compared to the contralateral limb. In the tibia, loss of bone mass in the ipsilateral limb was reduced to 1.4% (LOW), 1.4% (MED), and 2.4% (HI) compared to the contralateral. OPG also decreased the amount of tibial endocortical resorption compared to the Plac NC group. In summary, OPG mitigated bone loss caused by damage to the sciatic nerve. © 2001 Orthopaedic Research Society. Published by Elsevier Science Ltd. All rights reserved.