bluuebunny/crossref_metadata_2025_split huggingface dataset:
Value creation and destruction in social marketing services: a review and research agenda
Authors: Zainuddin Nadia , Gordon Ross 
Published: May 2020

Purpose
This paper aims to provide a review of the extant literature on value creation and destruction in social marketing services for social change, for the purposes of developing a research agenda for future research in this area. Creating value in social marketing services is now identified as a key focus for social marketing (Russell-Bennett et al., 2009; Domegan et al., 2013), yet work in this area is nascent and conceptual, methodological, and empirical work is needed to advance the research agenda (Zainuddin et al., 2013; 2016).

Design/methodology/approach
To help shape the future of research on value in social marketing services, this paper appraises the contributions of the current research literature, and identifies gaps in the current knowledge. A systematic literature review was conducted, following the PRISMA protocol for conducting and reporting systematic reviews (Moher et al., 2009). The review covers the areas of value creation in social marketing, value destruction in social marketing, dimensions of value in social marketing, and from value-in-exchange, to value-in-use, to value-in-behaviour in social change.

Findings
A research agenda for further work in this area is provided within the themes of 1. conceptual development, 2. broadening ontological, epistemological, and methodological foundations, 3. research contexts, and 4. measuring and evaluating value in social marketing services. Within each of these themes, a series of research questions are provided to guide further work in the four identified themes.

Originality/value
This paper is the first to offer a review of the extant literature on value creation and destruction in social marketing and social marketing services, and offer a research agenda for future work in this area. This paper contributes to services marketing and the development of service thinking as key component of social marketing, and the role that value creation plays in this (Russell-Bennett et al., 2013).
Responsible leadership and triple-bottom-line performance—do corporate reputation and innovation mediate this relationship?
Authors: Javed Muzhar , Ali Hafiz Yasir , Asrar-ul-Haq Muhammad , Ali Moazzam , Kirmani Syed Ali Ashiq 
Published: May 2020

PurposeDrawing on stakeholder theory and contingency theory, this study empirically investigates the relationship between responsible leadership (RL) and each dimension of triple-bottom-line (TBL) performance. Moreover, we tested the mediating effect of corporate reputation (CR) and innovation between RL and TBL performance.Design/methodology/approachPerceptual data were collected from 227 senior-level Pakistani managers using a questionnaire survey. Structural equation modeling (SEM) was used to test the direct and mediating effect hypotheses.FindingsThe results revealed that RL significantly and positively affects each dimension of TBL performance. Further, innovation mediated the relationship between RL and each dimension of TBL performance. However, CR did not mediate the relationship between RL and environmental performance.Originality/valueThis is maiden study to empirically investigate the effect of RL on meso-level outcome. Further, this study would be among the few ones to use TBL as a measure of corporate performance. Moreover, it will be the first study to test the mediating role of CR and innovation in the above-mentioned relationship and will also validate contingency theory.
Marginality and team building in collaborative crowdsourcing
Authors: Wang Rong 
Published: May 2020

PurposeExisting studies on crowdsourcing have focused on analyzing isolated contributions by individual participants and thus collaboration dynamics among them are under-investigated. The value of implementing crowdsourcing in problem solving lies in the aggregation of wisdom from a crowd. This study examines how marginality affects collaboration in crowdsourcing.Design/methodology/approachWith population level data collected from a global crowdsourcing community (openideo.com), this study applied social network analysis and in particular bipartite exponential random graph modeling (ERGM) to examine how individual level marginality variables (measured as the degree of being located at the margin) affect the team formation in collaboration crowdsourcing.FindingsSignificant effects of marginality are attributed to collaboration skills, number of projects won, community tenure and geolocation. Marginality effects remain significant after controlling for individual level and team level attributes. However, marginality alone cannot explain collaboration dynamics. Participants with leadership experience or more winning ideas are also more likely to be selected as team members.Originality/valueThe core contribution this research makes is the conceptualization and definition of marginality as a mechanism in influencing collaborative crowdsourcing. This study conceptualizes marginality as a multidimensional concept and empirically examines its effect on team collaboration, connecting the literature on crowdsourcing to online collaboration.
Sleep disturbances in adults with frailty and sarcopenia
Authors: Chiba Reona , Ohashi Yuki , Ozaki Akiko 
Published: May 2020

Purpose
Several epidemiological studies have reported an age-related increase in the prevalence of sleep disturbances. This study aims to investigate the relationship between sleep and sarcopenia/frailty in older adults and clarify issues that remain to be addressed in future studies.

Design/methodology/approach
PubMed was searched for relevant studies with the following keywords in the title: “sleep” and “sarcopenia” or “sleep” and “frailty.” A total of 15 studies published in English between 1998 and 2018 were reviewed.

Findings
Among the four studies that examined the relationship between sarcopenia and sleep, two reported that long or short sleep duration increased the risk of sarcopenia and this association was more pronounced in women than men. Among the seven studies examining the relationship between frailty and sleep, four reported that higher Pittsburgh Sleep Quality Index (PSQI) scores were associated with an increased risk of frailty.

Practical implications
Most previous studies have focused on interventions targeting a single area such as muscle strength or exercise habits, in older adults at risk for frailty. The results suggest that interventions targeting improved sleep may positively impact the maintenance of muscle strength.

Originality/value
The literature review revealed that too much or too little sleep increases the risk of sarcopenia in older adults. Further, sleep deprivation, greater night-time wakefulness and reduced sleep quality increase the risk of frailty. Interestingly, the risk of mortality is increased in individuals with daytime functional disorders such as excessive drowsiness or napping habits.
Review on sensitive and selective ethylene detection methods for fruit ripening application
Authors: Kathirvelan Jayaraman , Vijayaraghavan Rajagopalan 
Published: May 2020

Purpose
This work encompasses the various laboratory-based and portable methods evolved in recent times for sensitive and selective detection of ethylene for fruit-ripening application. The role of ethylene in natural and artificial fruit ripening and the associated health hazards are well known. So there is a growing need for ethylene detection. This paper aims to highlight potential methods developed for ethylene detection by various researchers, including ours. Intense efforts by various researchers have been on since 2014 for societal benefits.

Design/methodology/approach
The paper focuses on types of sensors, fabrication methods and signal conditioning circuits for ethylene detection in ppm levels for various applications. The authors have already designed, developed a laboratory-based set-up belonging to the electrochemical and optical methods for detection of ethylene.

Findings
The authors have developed a carbon nanotube (CNT)-based chemical sensor whose performance is higher than the reported sensor in terms of material, sensitivity and response, the sensor element being multi-walled carbon nanotube (MWCNT) in comparison to single-walled carbon nanotube (SWCNT). Also the authors have developed infrared (IR)-based physical sensor for the first time based on the strong IR absorption of ethylene at 10.6 µm. These methods have been compared with literature based on comparable parameters. The review highlights the potential possibilities for development of portable device for field applications.

Originality/value
The authors have reported new chemical and physical sensors for ethylene detection and quantification. It is demonstrated that it could be used for fruit-ripening applications A comparison of reported methods and potential opportunities is discussed.
A Systematic Literature Review on ICT Architectures for Smart Mauritian Local Council
Authors: Gobin-Rahimbux Baby , Cadersaib Zarine , Chooramun Nitish , Gooda Sahib-Kaudeer Nuzhah , Heenaye-Mamode Khan Maleika , Cheerkoot-Jalim Sudha , Kishnah Somveer , Elaheeboccus Shabneez 
Published: May 2020

Purpose
Cities have recognised information and communication technology (ICT) as a major enabler for transforming into “smarter” service providers. Mauritius is considering embarking on a smart island initiative, and as such, the existing towns in Mauritius have a major role to play in the transformation process. This study aims to focus on a systematic analysis of ICT architectures. This study proposes recommendations with regard to ICT infrastructures. This study elicits the contribution of those services towards the overall transformation of the towns, which in turn will form an integral part of the smart island initiative of the country.

Design/methodology/approach
A first step towards developing a smart ICT architecture is to understand what a smart ICT architecture constitutes of and the frameworks that can be used to develop these architectures. The main objectives of this systematic literature review (SLR) are as follows: understand what a smart ICT architecture consists of and derive a definition that will be used throughout the research for the development of ICT architecture for the smart local councils for Mauritius; analyse various frameworks, architectures and models that have been used in existing literature for the development of smart ICT architectures.

Findings
This SLR was conducted with a view to investigate ICT architectures with respect to smart governance. An in-depth review, followed by a critical analysis was performed based on the research questions set. The contribution of this study include the formulation of a definition for ICT architecture for smart local councils, which can be applied to any sphere characterised by similar aspects with reference to smart local governance. Albeit existing frameworks such as The Open Group Architecture Framework, Federal Enterprise Architecture and Zachman Framework, it was observed that in most cases, ICT architectures were built from scratch potentially because of specificities of each country/city.

Originality/value
This work proposes ICT architectures for smart local council.
Interorganizational learning: a bibliometric review and research agenda
Authors: Anand Amitabh , Brøns Kringelum Louise , Øland Madsen Charlotte , Selivanovskikh Louisa 
Published: May 2020

PurposeScholarly interest in interorganizational learning (IOL) has spiked in the past decade because of its potential to absorb, transfer and create valuable knowledge for enhanced innovative performance and sustained competitive advantage. However, only a handful of review studies exists on the topic. The evolution of IOL has not been studied explicitly and there is a lack of understanding of the field trends. To fill this gap, this paper aims to comprehensively review the literature on IOL and map its evolution and trends using bibliometric techniques. In particular, the authors use visualization of science mapping freeware to systematize the findings and interpret the results.Design/methodology/approachThe authors synthesize the findings using “evaluative bibliometric techniques” to identify the quality and quantity indicators of the IOL research and use “relational bibliometric techniques” to determine the structural indicators of the IOL field such as the intellectual foundations and emerging research themes of IOL research.FindingsThrough an analysis of 208 journal publications obtained from the Scopus database, the authors determine the leading authors, countries, highly cited papers and their contributions to the IOL literature. By identifying the key hotspots, intellectual foundations and emerging trends of IOL, the authors provide promising avenues in IOL research.Originality/valueTo the best of the knowledge, this study is the first to systematically review the IOL literature and provide future research directions.
Vesiduction: the fourth way of HGT
Authors: Soler Nicolas , Forterre Patrick 
Published: May 2020

SummaryBesides the canonical gene transfer mechanisms transformation, transduction and conjugation, DNA transfer involving extracellular vesicles is still under appreciated. However, this widespread phenomenon has been observed in the three domains of life. Here, we propose the term ‘Vesiduction’ as a fourth mode of intercellular DNA transfer.
Exogenous maltose enhances Zebrafish immunity to levofloxacin‐resistant Vibrio alginolyticus
Authors: Jiang Ming , Yang Lifen , Chen Zhuang‐gui , Lai Shi‐shi , Zheng Jun , Peng Bo 
Published: May 2020

SummaryUnderstanding the interplay between bacterial fitness, antibiotic resistance, host immunity and host metabolism could guide treatment and improve immunity against antibiotic‐resistant pathogens. The acquisition of levofloxacin (Lev) resistance affects the fitness of Vibrio alginolyticus in vitro and in vivo. Lev‐resistant (Lev‐R) V. alginolyticus exhibits slow growth, reduced pathogenicity and greater resistance to killing by the host, Danio rerio (zebrafish), than Lev‐sensitive (Lev‐S) V. alginolyticus, suggesting that Lev‐R V. alginolyticus triggers a weaker innate immune response in D. rerio than Lev‐S V. alginolyticus. Differences were detected in the metabolome of D. rerio infected with Lev‐S or Lev‐R V. alginolyticus. Maltose, a crucial metabolite, is significantly downregulated in D. rerio infected with Lev‐R V. alginolyticus, and exogenous maltose enhances the immune response of D. rerio to Lev‐R V. alginolyticus, leading to better clearance of the infection. Furthermore, we demonstrate that exogenous maltose stimulates the host production of lysozyme and its binding to Lev‐R V. alginolyticus, which depends on bacterial membrane potential. We suggest that exogenous exposure to crucial metabolites could be an effective strategy for treating and/or managing infections with antibiotic‐resistant bacteria.
Treatment patterns among patients with malignant pleural mesothelioma: An Italian, population‐based nationwide study
Authors: Trama Annalisa , Proto Claudia , Signorelli Diego , Garassino Marina C. , Lo Russo Giuseppe , Ganzinelli Monica , Prelaj Arsela , Mensi Carolina , Gangemi Manuela , Gennaro Valerio , Chellini Elisabetta , Caldarella Adele , Angelillo Italo F. , Ascoli Valeria , Pascucci Cristiana , Tagliabue Giovanna , Cusimano Rosanna , Bella Francesca , Falcini Fabio , Merler Enzo , Masanotti Giuseppe , Ziino Antonio , Michiara Maria , Gola Gemma , Storchi Cinzia , Mangone Lucia , Vitale Maria F. , Cirilli Claudia , Tumino Rosario , Scuderi Tiziana , Fanetti Anna C. , Piffer Silvano , Tiseo Marcello , Gatta Gemma , Botta Laura ,   the LUME study WG
Published: May 2020

AbstractBackgroundMalignant pleural mesothelioma (MPM) is a rare cancer with a poor prognosis. Centralization of rare cancer in dedicated centers is recommended to ensure expertise, multidisciplinarity and access to innovation. In Italy, expert centers for MPM have not been identified in all regions. We aimed to describe the treatment patterns among MPM patients across different Italian regions and to identify factors associated with the treatment patterns across the regions.MethodsWe performed an observational study on a random sample of 2026 MPM patients diagnosed in 2003–2008. We included 26 population‐based registries covering 70% of the Italian population. To identify factors associated with treatment patterns, across the different regions, we fitted a multinomial logistic regression model adjusted by age, sex, stage, histology and hospital with thoracic surgical department.ResultsMPM patients mostly received chemotherapy alone (41%) or no cancer‐directed therapy (36%) especially the older patients. The first course of treatment for MPM patients differed across regions. Patients from Piedmont, Liguria and Campania were more likely to receive no cancer‐directed therapy; those living in Tuscany and Sicily were more likely to get surgery; patients from Marche and Lazio were more likely to receive chemotherapy. These differences were not explained by age, sex, stage, histology and availability of a thoracic surgery department.ConclusionsThere is limited expertise available and lack of a network able to maximize the expertise available may contribute to explaining the results of our study. Our findings support the need to ensure the appropriate care of all MPM patients in reorganizing the health care services.Key pointsSignificant findings of the study:MPM patients mostly received chemotherapy alone or no cancer‐directed therapy especially the older patients. The first course of treatment for MPM patients differed across Italian regions.What this study adds:Differences in MPM clinical management are not explained by the age, stage, histology nor by the availability of a thoracic surgery department. Limited expertise for MPM contribute to explaining the unequal access to appropriate care for MPM patients in Italy.
microRNA‐100 functions as a tumor suppressor in non‐small cell lung cancer via regulating epithelial‐mesenchymal transition and Wnt/β‐catenin by targeting HOXA1
Authors: Han Weizhong , Ren Xiaoxia , Yang Yupeng , Li Haixia , Zhao Lin , Lin Zhaoxia 
Published: May 2020

BackgroundNon‐small cell lung cancer (NSCLC) is a leading subtype in lung cancer, with high morbidities and mortalities worldwide. microRNA (miRNA) has appeared to play indispensable roles in a variety of solid carcinomas. The current study focused on the functions of miR‐100 in NSCLC.MethodsqRT‐PCR was performed to detect miR‐100 and HOXA1 expressions in NSCLC tissues and cells. MTT and transwell assays were used to determine the functions of miR‐100 in NSCLC cell proliferation, invasion and migration abilities. Western blot was used to measure related protein expressions.ResultsqRT‐PCR results showed that miR‐100 expressions were dramatically decreased in NSCLC tissues. MTT assays indicated that miR‐100 restoration inhibited NSCLC cell proliferation. Furthermore, transwell assay was performed to determine the impacts of miR‐100 on NSCLC invasion and migration abilities. As expected, the invasion and migration capacities were significantly repressed. Direct interactions between HOXA1 and miR‐100 were also verified via dual‐luciferase reporter assays. Western blot analysis demonstrated that miR‐100 exerted suppressive functions via regulating EMT and Wnt/β‐catenin in NSCLC cells.ConclusionsOur results showed that miR‐100 served antitumor roles in NSCLC, providing new evidence of miR‐100 as a promising therapeutic biomarker in NSCLC.
Maternal host responses to poly(I:C) during pregnancy leads to both dysfunctional immune profiles and altered behaviour in the offspring
Authors: Garcia‐Valtanen Pablo , van Diermen Bianca A. , Lakhan Nerissa , Lousberg Erin L. , Robertson Sarah A. , Hayball John D. , Diener Kerrilyn R. 
Published: May 2020

AbstractProblemAutism spectrum disorder (ASD)‐like phenotypes in murine models are linked to elevated pro‐inflammatory cytokine profiles caused by maternal immune activation (MIA), but whether MIA alters the immune response in the offspring remains unclear.Method of studyPolyinosinic:polycytidylic acid (poly:[IC]) was used to induce MIA in immunocompetent and control TLR3‐deficient pregnant mice, and cytokine levels were measured in maternal and foetal organs. Furthermore, cytokines and behaviour responses were tested after challenge with lipopolysaccharide in 7‐day‐old and adult mice.ResultsMIA induced on E12 resulted in changes in the cytokine expression profile in maternal and foetal organs and correlated with TNFα and IL‐18 dysregulation in immune organs and brains from neonatal mice born to MIA‐induced dams. Such changes further correlated with altered behavioural responses in adulthood.ConclusionMIA induced by pathogens during pregnancy can interfere with the development of the foetal immune and nervous systems leading to dysfunctional immune responses and behaviour in offspring.
In vivo evaluation of Vivere bovine pericardium valvular bioprosthesis with a new anti‐calcifying treatment
Authors: Braile‐Sternieri Maria C. V. B. , Goissis Gilberto , Giglioti Aparecida de F. , Ramirez Vladimir D. A. , Pereira Nathalia P. , de Vasconcellos Adriano , Basso‐Frazzato Glaucia G. , Braile Domingo Marcolino 
Published: May 2020

AbstractThe objective of this study was to evaluate the effect of chemical treatment with glutamic acid to avoid calcification of biological cardiac valves. The bovine pericardium (BP) tissues were fixed with 0.5% glutaraldehyde (BP/GA), followed by treatment with glutamic acid (BP/GA + Glu) for neutralization of the free aldehyde groups. Microscopic analysis showed that the wavy structure of collagen fibrils was preserved, but changes in elastin's integrity occurred. However, the treatment did not promote undesirable changes in the thermal and mechanical properties of the modified BPs. These samples were systematically studied in rat subcutaneous tissue: control (BP/GA) and anticalcificant (BP/GA + Glu). After 60 days, both groups induced similar inflammatory reactions. In terms of calcification, BP/GA + Glu remained more stable with a lower index (3.1 ± 0.2 μg Ca2+/mg dry tissue), whereas for BP/GA it was 5.7 ± 1.3 μg Ca2+/mg dry tissue. Bioprostheses made from BP/GA + Glu were implanted in the pulmonary position in sheep, and in vivo echocardiographic analyses revealed maintenance of valvar function after 180 days, with low gradients and minimal valve insufficiency. The explanted tissues of the BP/GA + Glu group had a lower average calcium content 3.8 ± 3.0 μg Ca2+/mg dry tissue. The results indicated high anticalcification efficiency of BP/GA + Glu in both subcutaneous implant in rats and in the experimental sheep model, which is an advantage that should encourage the industrial application of these materials for the manufacture of bioprostheses.