bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using Technology to Support Expectant and Parenting Youth through Case Management: Lessons Learned in the Field
Authors: Kang Nichole , Patrick Morgan , Williams Frances , Hemady Katharine , Aussendorf Mara , Greenbacker Livia , Kannam Allison 
Published: May 2020

Abstract
Introduction
The Support. Empower. Learn. Parenting Health Initiative (SELPHI) provides expectant and parenting youth ages 16–24 in Philadelphia with supports to improve educational, social, and economic outcomes to shape their health and the health of their children. Phone, text, video-based, and social media communication technology is built in to SELPHI’s program design to facilitate case management and connect clients to a broad referral network. Given the novelty of using information and communication technology (ICT) in case management, the reported lessons learned seek to give providers a specific and nuanced picture of ICT in case management.

Methods
In its initial 6-month implementation period, SELPHI’s five case managers, called Navigators, served 59 clients. Data from feedback surveys and case records were collected from clients and Navigators. Data included client demographic characteristics, needs assessment, and contact records to inform continuous quality improvement (CQI).

Results
ICT’s benefits included having multiple ways to connect to difficult-to-reach clients, the ability to be more responsive to clients, and the flexibility to address scheduling and transportation barriers. ICT’s challenges are related to Navigators’ boundary setting, limitations on rapport building, and data security considerations. CQI data are presented to illustrate the lessons learned. Text messages were the most prevalent ICT; phone calls were most successful in engaging clients. Clients’ ICT preferences differed by purpose of communication.

Discussion
Findings suggest that programs should understand the nuances of client contact preferences. To maximize the benefits of ICT, programs must develop or adapt protocols based on preference and purpose of communication.
CCL20 induced by visfatin in macrophages via the NF-κB and MKK3/6-p38 signaling pathways contributes to hepatic stellate cell activation
Authors: Heo Yu Jung , Choi Sung-E , Lee Nami , Jeon Ja Young , Han Seung Jin , Kim Dae Jung , Kang Yup , Lee Kwan Woo , Kim Hae Jin 
Published: May 2020

AbstractChemokines interact with hepatic resident cells during inflammation and fibrosis. CC chemokine ligand (CCL) 20 has been reported to be important in inflammation and fibrosis in the liver. We hypothesized that visfatin, an adipocytokine, could play a role in hepatic fibrosis via CCL20. We investigated the effect of visfatin on CCL20 in THP-1 human promonocytic cells and examined the molecular mechanisms involved. Following treatment of THP-1 cells with visfatin, CCL20 expression and secretion were assessed. We assessed the intracellular signaling molecules IKK/NF-κB, JAK2/STAT3, MAPKs, and MKK3/6 by western blotting. We treated THP-1 cells with visfatin and signaling inhibitors, and examined CCL20 mRNA and protein levels. To investigate the effect of visfatin-induced CCL20 expression in hepatic stellate cells (HSCs), LX-2 cells were co-cultured with the culture supernatant of THP-1 cells with or without anti-CCL20 neutralizing antibodies, and fibrosis markers were examined by RT-PCR and immunoblotting. In THP-1 cells, visfatin increased the CCL20 mRNA and protein levels. visfatin increased the activities of the NF-κB, p38, and MLK3/6 signaling pathways but not those of the JAK2/STAT3 and ERK pathways. Visfatin treatment together with an NF-κB, p38, or MLK3 inhibitor reduced the mRNA and protein levels of CCL20. The visfatin-induced CCL20 increased the expression of fibrosis markers and CCR6 in HSCs. Following neutralization of CCL20, the levels of fibrosis markers and CCR6 were decreased. Visfatin increases the expression of CCL20 via the NF-κB and MKK3/6-p38 signaling pathways in macrophages, and visfatin-induced CCL20 expression promotes the fibrosis markers in HSCs.
Nonrestorative sleep scale: a reliable and valid short form of the traditional Chinese version
Authors: Li S. , Fong D. Y. T. , Wong J. Y. H. , Wilkinson K. , Shapiro C. , Choi E. P. H. , McPherson B. , Lau E. Y. Y. , Lam C. L. K. , Huang L. X. , Ip M. S. M. 
Published: May 2020

Abstract
Purpose
Previous research has suggested the essential unidimensionality of the 12-item traditional Chinese version of the Nonrestorative Sleep Scale (NRSS). This study aimed to develop a short form of the traditional Chinese version of the NRSS without compromising its reliability and validity.

Methods
Data were collected from 2 cross-sectional studies with identical target groups of adults residing in Hong Kong. An iterative Wald test was used to assess differential item functioning by gender. Based on the generalized partial credit model, we first obtained a shortened version such that further shortening would result in substantial sacrifice of test information and standard error of measurement. Another shortened version was obtained by the optimal test assembly (OTA). The two shortened versions were compared for test information, Cronbach’s alpha, and convergent validity.

Results
Data from a total of 404 Chinese adults (60.0% female) who had completed the Chinese NRSS were gathered. All items were invariant by gender. A 6-item version was obtained beyond which the test performance substantially deteriorated, and a 9-item version was obtained by OTA. The 9-item version performed better than the 6-item version in test information and convergent validity. It had discrimination and difficulty indices ranging from 0.44 to 2.23 and − 7.58 to 2.13, respectively, and retained 92% of the test information of the original 12-item version.

Conclusion
The 9-item Chinese NRSS is a reliable and valid tool to measure nonrestorative sleep for epidemiological studies.
Assessment of Structural Monitoring by Analyzing Some Modal Parameters: An Extended Inventory of Methods and Developments
Authors: Rebenciuc Mihai , Bibic Simona Mihaela , Toma Antonela 
Published: May 2020

AbstractThe SHM (structural health monitoring) evaluation consists to determining the modes (resonances) of vibration characteristic of the structure and each of them is represented by its modal parameters which can be obtained experimentally and can be analyzed by different procedures. In the present paper (except subsections 2.1.1, 3.1.1) the coefficients (including the coefficient of displacement) are constant; in this regard, it is made an inventory of some methods of classical and non-classical mathematics with the specific computing scheme. All methods of classical mathematics that were considered, i.e., second-order linear nonhomogeneous differential equations, Laplace operational method, analytical conditional form, approximations with error evaluation (according to contraction principle) are inventoried and then developed—and the first two methods by comparison. As methods of the non-classical mathematics the dyadic wavelet method, the approximation (transform) fuzzy method and the grammatical evolution method are inventoried and then the first is developed. In addition, there are illustrated the calculus techniques by few examples and also computing wavelet coefficients for healthy and damaged structures. Notice that in the subsection 2.1.1 in which the coefficients (including the coefficient of displacement) are considered variable there are some transformations of (non)homogeneous equations in the scaled forms. In addition in the subsection 3.1.1 exact solutions, respectively approximations with error evaluation (according to contraction principle) relative to remarkable equations in literature (including the corresponding standard form) are obtained by using the results of 2.1.1.
Using Person-Reported Outcomes (PROs) to Motivate Young People with Diabetes
Authors: de Wit Maartje , Versloot Judith , Zenlea Ian , Goethals Eveline R. 
Published: May 2020

AbstractPurpose of ReviewThis manuscript describes how person-reported outcomes (PROs) can be utilized in care for young people with diabetes in the context of motivation.Recent FindingsThe use of person-reported outcome measures (PROMS) in clinical care is feasible and acceptable, and helps focus the clinical encounter on life domains important to the person with diabetes. Results with regard to impact on self-management and glycemic outcomes are limited. Motivation is an important factor for self-management. Based on self-determination theory, autonomy-supportive, person-centered, and collaborative communication by diabetes care providers is associated with better outcomes. PROMs can facilitate this conversation.SummaryUnderstanding of youth motivation for maintaining or improving self-management behaviors requires a person-centered approach. PROMs can be used to facilitate an autonomy-supportive and person-centered conversation in clinical care. Training diabetes care providers in autonomy-supportive, person-centered conversation skills to discuss PROs might help to tap into youth’s motivation, but further research is needed.
From Psoriasis to Psoriatic Arthritis: Insights from Imaging on the Transition to Psoriatic Arthritis and Implications for Arthritis Prevention
Authors: Zabotti Alen , Tinazzi Ilaria , Aydin Sibel Zehra , McGonagle Dennis 
Published: May 2020

AbstractPurpose of ReviewTo describe the recent advances in the field towards the prevention and early recognition of Psoriatic Arthritis (PsA).Recent FindingsDefining the preclinical phase of PsA remains challenging since up to 50% of subjects with psoriasis have subclinical imaging enthesopathy, but many of these do not progress to PsA. Nevertheless, there is evidence that subjects with subclinical imaging enthesopathy are at increased risk of developing PsA. In recent years, it has been shown that both PsA and anti-citrullinated protein antibodies (ACPA) positive rheumatoid arthritis (RA) are characterized by a subclinical phase of non-specific or brief duration arthralgia with shared imaging features accounting for joint symptomatology. Sonographically determined tenosynovitis and enthesitis are the key imaging features present in non-specific PsO arthralgia that are at risk of future PsA development. Furthermore, the early phases of PsA are complicated by factors including body mass index (BMI), which is a risk factor for PsA, but BMI is also associated with imaging abnormalities on enthesopathy. Fully disentangling these clinical and imaging factors will be important for enrichment for imminent PsA so that disease prevention strategies can be investigated.SummaryPsoriasis patients with arthralgia have a higher prevalence of tenosynovitis and imaging enthesopathy is at higher risk of transitioning to overt PsA.
Thioredoxin System Protein Expression Is Associated with Poor Clinical Outcome in Adult and Paediatric Gliomas and Medulloblastomas
Authors: Yao Anqi , Storr Sarah J. , Al-hadyan Khaled , Rahman Ruman , Smith Stuart , Grundy Richard , Paine Simon , Martin Stewart G. 
Published: May 2020

AbstractThe thioredoxin (Trx) system is an important enzyme family that regulates cellular redox homeostasis. Protein expression of Trx system family members has been assessed in various cancers and linked to various clinicopathological variables, disease progression, treatment response and survival outcomes but information is lacking in brain tumours. Expression of the system was therefore examined, by immunohistochemistry in different brain tumour types, adult and paediatric cases, to determine if expression was of importance to clinical outcome. Trx system proteins were expressed, to variable levels, across all brain tumour types with significant variations in expression between different tumour types/grades/regions. High Trx reductase (TrxR) expression was linked to worse prognosis across all cohorts. High cytoplasmic TrxR expression was significantly associated with adverse overall survival (OS) in adult glioblastoma (P = 0.027) and paediatric low-grade glioma (LGG) patients (P = 0.012). High expression of nuclear TrxR, cytoplasmic and nuclear Trx and Trx-interacting protein (TxNIP) was associated with improved OS in paediatric LGGs (P = 0.031, P < 0.001, P = 0.044 and P = 0.018, respectively). For patients with high-grade gliomas, both high cytoplasmic TrxR and Trx expression were associated with poor OS (P = 0.002 and P = 0.007, respectively). In medulloblastoma, high expression of cytoplasmic TrxR and Trx and nuclear Trx was associated with worse prognosis (P = 0.013, P = 0.033 and P = 0.007, respectively); with cytoplasmic TrxR and nuclear Trx remaining so in multivariate analysis (P = 0.009 and P = 0.013, respectively). The consistent finding that high levels of cytoplasmic TrxR are associated with a worse prognosis across all cohorts suggests that TrxR is an important therapeutic target in brain cancers.
Resource-harvester cycles caused by delayed knowledge of the harvested population state can be dampened by harvester forecasting
Authors: Adamson Matthew W. , Hilker Frank M. 
Published: May 2020

AbstractThe monitoring of ecosystems and the spread of information concerning their state among human stakeholders is often a lengthy process. The importance of mutual feedbacks between socioeconomic and ecological dynamics is being increasingly recognised in recent studies, but it is generally assumed that the feedback from the environment is instantaneous, ignoring any delay in the spread of ecosystem knowledge and the resulting potential for system stability loss. On the other hand, human actors rarely make purely myopic socioeconomic decisions as is often assumed. Rather, they show a degree of foresight for future utility which may have an opposing, stabilising effect to any delay in knowledge. In this paper, we consider a generic resource-harvester model with delayed ecosystem knowledge and predictive behaviour by the harvesters. We show that delays in the spread of information about the resource level can destabilise the bioeconomic equilibrium in the system and induce harvesting cycles or the collapse of the resource. Sufficiently farsighted prediction by the harvesters can stabilise the system, provided the delay is not too long. However, if the time horizon of prediction is too long relative to the timescale of resource growth, prediction can be destabilising even in the absence of delay. The results imply that effective monitoring of ecosystems and fast dissemination of the results are necessary for their sustainable use and that efforts to promote appropriate foresight among ecosystem users on the personal and institutional level would be beneficial to the stability of coupled socioeconomic-ecological systems.
The multivariate method strikes again: New power functions with low differential uniformity in odd characteristic
Authors: Felke Patrick 
Published: May 2020

AbstractLet f(x) = xd be a power mapping over $\mathbb {F}_{n}$

F

n

and $\mathcal {U}_{d}$

U

d

the maximum number of solutions $x\in \mathbb {F}_{n}$
x
∈

F

n

of ${\Delta }_{f,c}(x):=f(x+c)-f(x)=a\text {, where }c,a\in \mathbb {F}_{n}\text { and } c\neq 0$

Δ

f
,
c

(
x
)
:
=
f
(
x
+
c
)
−
f
(
x
)
=
a
, where

c
,
a
∈

F

n

and

c
≠
0
. f is said to be differentially k-uniform if $\mathcal {U}_{d} =k$

U

d

=
k
. The investigation of power functions with low differential uniformity over finite fields $\mathbb {F}_{n}$

F

n

of odd characteristic has attracted a lot of research interest since Helleseth, Rong and Sandberg started to conduct extensive computer search to identify such functions. These numerical results are well-known as the Helleseth-Rong-Sandberg tables and are the basis of many infinite families of power mappings $x^{d_{n}},n \in \mathbb {N},$

x

d

n

,
n
∈
ℕ
,
of low uniformity (see e.g. Dobbertin et al. Discret. Math. 267, 95–112 2003; Helleseth et al. IEEE Trans. Inform Theory, 45, 475–485 1999; Helleseth and Sandberg AAECC, 8, 363–370 1997; Leducq Amer. J. Math. 1(3) 115–123 1878; Zha and Wang Sci. China Math. 53(8) 1931–1940 2010). Recently the crypto currency IOTA and Cybercrypt started to build computer chips around base-3 logic to employ their new ternary hash function Troika, which currently increases the cryptogrpahic interest in such families. Especially bijective power mappings are of interest, as they can also be employed in block- and stream ciphers. In this paper we contribute to this development and give a family of power mappings $x^{d_{n}}$

x

d

n

with low uniformity over $\mathbb {F}_{n}$

F

n

, which is bijective for p ≡ 3 mod 4. For p = 3 this yields a family $x^{d_{n}}$

x

d

n

with $3\leq \mathcal {U}_{d_{n}}\leq 4,$
3
≤

U

d

n

≤
4
,
where the family of inverses has a very simple description. These results explain “open entries” in the Helleseth-Rong-Sandberg tables. We apply the multivariate method to compute the uniformity and thereby give a self-contained introduction to this method. Moreover we will prove for a related family of low uniformity introduced in Helleseth and Sandberg (AAECC, 8 363–370 1997) that it yields permutations.
Socio-Economic Differences in the Development of Six-Year-Old Children in Rural Areas of East Poland
Authors: Jopkiewicz Andrzej , Nowak Stanisław Bogdan , Jopkiewicz Agata Maria , Lelonek Magdalena 
Published: May 2020

AbstractThe aim of this study is to evaluate socio-economic differences in physical, cognitive, and motor development among six-year-old children living in rural areas. The study encompassed 228 children, including 118 girls and 110 boys living in different rural settlements in the Świętokrzyskie Province in Poland, who were selected through a combination of nonprobability and random sampling. The study was carried out from April to June 2014. A questionnaire was used to collect information from the parents of the children concerning the parents’ education, number of children in the family, and the number of persons per room. Based on the concept of socio-economic status (SES), three levels of quality of life conditions of each family, i.e., high, average, and low, were distinguished. The study noted considerable differences in BMI, and especially the cognitive development of the children with respect to the socio-economic status of their family. It was observed that children from rural areas who live in bad socio-economic conditions are exposed to a wide range of negative factors affecting their health, which leads to lower educational results and negative long-term biological and psychosocial consequences. The chance for more rapid alignment of development deficits for those children would have been their earlier cover of school duty.
Accuracy of the UAV-Based DEM of Beach–Foredune Topography in Relation to Selected Morphometric Variables, Land Cover, and Multitemporal Sediment Budget
Authors: Rotnicka Joanna , Dłużewski Maciej , Dąbski Maciej , Rodzewicz Mirosław , Włodarski Wojciech , Zmarz Anna 
Published: May 2020

AbstractRecent developments in unmanned aerial vehicles (UAVs) have resulted in high-resolution digital elevation models (DEMs) of vulnerable coastal environments, including beach–foredune topography. If performed repetitively, they can offer an excellent tool to determine the spatial and temporal changes in the sediment budget, which may be required for proper land management. However, the quality of a UAV, slope parameters, and vegetation significantly influence DEM accuracy. The aim of this study is to compare precise GPS-RTK transects across a section of the South Baltic coast in Poland with those obtained from a DEM based on high-resolution and high-accuracy images obtained by a wind-resistant, high-quality fixed-wing UAV during beyond visual line of sight operation (BVLOS). Different land cover classes, slope inclination, and general curvature, as well as surface roughness, were taken into consideration as possible factors influencing the uncertainty. The study revealed that marram grass greatly affects the accuracy of the UAV-derived model and that the uncertainty of the UAV-derived DEM increases together with increasing slope inclination and, to a lesser degree, with increasing general slope curvature. We showed that sediment budget determinations with the use of a UAV-based DEM are correct only where grass cover is sparse, in our study, up to 20% of the area.
From ice to space: a greenhouse design for Moon or Mars based on a prototype deployed in Antarctica
Authors: Maiwald Volker , Vrakking Vincent , Zabel Paul , Schubert Daniel , Waclavicek René , Dorn Markus , Fiore Lorenzo , Imhof Barbara , Rousek Tomas , Rossetti Vittorio , Zeidler Conrad 
Published: May 2020

AbstractThe future of human space exploration is aimed at long-term missions to Moon and Mars. Currently, plans are elaborated by NASA, ESA, CNSA and others for a return to the lunar environment within the next decade as an intermediate step towards the goal of reaching the surface of Mars. For sustenance and crew comfort the crew of such long-duration missions should be provided with fresh food on the lunar or Martian surface. Due to the associated power demand, the required resources and technological complexity, this is a major challenge for this kind of missions. To continuously provide fresh food without the need for cargo transfer from Earth towards Moon or Mars an on-site greenhouse system is required, producing the fresh food in situ. The associated effort and cost for all resources to be transported to the base of operation prohibit any waste of resources, requiring a system operating in a (nearly) closed loop. Developing and validating a prototype for an effective and efficient greenhouse, labeled future exploration greenhouse (FEG) for space exploration has been the goal of the EDEN ISS project, funded by the EU, in the past 4 years. This paper shows the results of a design elaboration of the FEG into a greenhouse for planetary deployment on Moon or Mars. Guided by lessons learned from operating the FEG in Antarctica for one year and based on assumptions concerning the mission scenario, e.g. assuming an existing base infrastructure on-site, the presented design incorporates a plant growth area which is more than a factor of two larger than the prototype. The total mass of the cylindrical system, including equipment required during launch, transfer and landing, is about 19 mT, fitting into a Falcon 9 launcher. The versatile design is compatible with a wide variety of mission scenarios, e.g. ESA’s Moon Village, and currently public mission plans.
Duloxetine-Induced Neural Cell Death and Promoted Neurite Outgrowth in N2a Cells
Authors: Gao Wanli , Chen Rui , Xie Nan , Tang Daolin , Zhou Borong , Wang Ding 
Published: May 2020

AbstractDuloxetine is a clinical drug that is primarily used for treatment of depression and pain, but it has side effects of addiction and tolerance. Cytochrome P450 (CYP) is its metabolic enzyme, and the drug’s biofunction results from its neuro-protective effect in animal and cell models. We aimed to investigate the duloxetine-induced neural cytotoxicity effect and its performance in an N2a cell neurite outgrowth model. Cell death was assessed as cell viability using a Cell Count Kit-8 and further evaluated using bright-field images, propidium iodide (PI) and annexin V staining, colony-formation analysis, TUNEL staining of the cells, and biochemical testing. N2a cells were committed to differentiation by serum withdrawal and RA induction, and the neurite outgrowth was evaluated as the number of differentiated cells, longest neurite length, and average neurite length. Cell cycle analysis, PI and annexin V staining, mRNA expression, and biochemical testing were used to evaluate the drug effects on differentiation. The induction of neural cell death by duloxetine was not affected by classic cell death inhibitors but was promoted by the CYP inducer rifampicin. N2a cell neurite outgrowth was promoted by duloxetine via reduction of the CYP2D6 and MDA levels and induction of Bdnf protein levels. Duloxetine induces neural cell death through effects on CYP and promotes N2a cell neurite outgrowth by regulating CYP, Bdnf protein, and the intracellular lipid peroxidation level.