bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Vancomycin MIC Creep Phenomenon in Methicillin-Resistant Staphylococcus aureus isolates in a Tertiary Care Hospital of Lahore
Authors: Arshad Faiqa , Saleem Sidrah , Jahan Shah , Tahir Romeeza 
Published: September 2020

Objective: To assess vancomycin MIC creep phenomenon in methicillin-resistant Staphylococcus aureus isolated from clinical specimens.
Methods: This descriptive study was conducted in Microbiology department of University of Health Sciences, Lahore from January 2016- December 2019. In this study, vancomycin MICs were revealed by E test method for clinical MRSA strains. For the final evaluation, a single isolate from each patient was taken. The reported vancomycin MICs results were used and the values were not rounded up to the next upward value. For every study year, MIC50, MIC90, median and geometrical mean MIC, percentages of susceptible and resistant strains were calculated.
Results: A total of 352 MRSA strains were isolated out of 2704 staphylococcal isolates. Our study showed elevated vancomycin MIC among MRSA isolates. The majority of isolates showed MIC values ≥1.5µg/ml. MIC50, MIC 90 was constant throughout four years period. However, geometric mean MIC increased gradually during the study period. The MIC greater than base year median was overall 17.3%. A complete shift can be observed between MIC “1.0” and “2.0” the percent of cases with MIC “1.0” decreased and with MIC “2.0” increased over time crossing each other in 2017.
Conclusion: Vancomycin MIC creep was identified in clinical isolates of MRSA, during four years of study period. Even though there is an absence of VISA and VRSA strains; this significant increase in vancomycin MIC trend is indeed worrying for the clinicians about the threat of potential failure of treatment in MRSA infections.
doi: https://doi.org/10.12669/pjms.36.7.3273
How to cite this:Arshad F, Saleem S, Jahan S, Tahir R. Assessment of Vancomycin MIC Creep Phenomenon in Methicillin-Resistant Staphylococcus aureus isolates in a Tertiary Care Hospital of Lahore. Pak J Med Sci. 2020;36(7):1505-1510. doi: https://doi.org/10.12669/pjms.36.7.3273
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The impact of environmental risk factors on delirium and benefits of noise and light modifications: a scoping review
Authors: Hashemighouchani Haleh , Cupka Julie , Lipori Jessica , Ruppert Matthew M. , Ingersent Elizabeth , Ozrazgat-Baslanti Tezcan , Rashidi Parisa , Bihorac Azra 
Published: September 2020

Background: To explore existing literature on the association between environmental risk factors and delirium, and to investigate the effectiveness of environmental modifications on prevention or management of delirium. Methods: This is a scoping review of peer-reviewed studies in PubMed and the reference lists of reviewed articles. Observational studies reporting the effect of noise, light, and circadian rhythm on delirium and interventional studies assessing delirium in modified environments were reviewed. Results: 37 studies were included, 21 of which evaluated the impact of environment on delirium and 16 studied possible solutions to mitigate those impacts. Mixed findings of the reviewed studies yielded inconclusive results; a clearly delineated association between high noise levels, abnormal amounts of light exposure, and sleep disruption with delirium could not be established. The environmental interventions targeted reducing noise exposure, improving daytime and mitigating night-time light exposure to follow circadian rhythm, and promoting sleep. The overall evidence supporting effectiveness of environmental interventions was also of a low confidence; however, quiet-time protocols, earplugs, and bright light therapy showed a benefit for prevention or management of delirium. Conclusions: Environmental modifications are non-invasive, risk-free, and low-cost strategies that may be beneficial in preventing and managing delirium, especially when used as part of a multi-component plan. However, given the limited evidence-based conclusions, further high-quality and larger studies focusing on environmental modifications and delirium outcomes are strongly recommended.
"Dein Ruhm wird wie ein Demantstein, ja wie ein fester Stahl beständig sein"
Authors: Maul Michael 
Published: September 2020

Der Artikel widmet sich eingangs den Beziehungen Johann Sebastian Bachs in seinem Leipziger Lebensumfeld und darüber hinaus und hinterfragt Bachs Beweggründe für die Pflege von Beziehungen. Dabei wird auf die hauptsächlich mangels Überlieferung entstehenden Schwierigkeiten hingewiesen, die den Versuch, diese Beziehungen Bachs nachzuvollziehen, erschweren. Speziell das Verhältnis der Familie zum kgl. preuß. Hofrat und Leibarzt Georg Ernst Stahl (1713-1772) wird untersucht. Als Indizien dienen Widmungen Carl Philipp manuel wie Wilhelm Friedemann Bachs an Stahl, der Aufenthalt J. S. Bachs im Hause Stahls in Berlin 1741 sowie besonders eine im Verzeichnis der Musikalien Stahls vermerkte Kantate J. S. Bachs. Diese wird als BWV 210 identifiziert, die Überlieferungsgeschichte dieses Werkes daraufhin neu formuliert und aus textlichen Verweisen und der Werkgeschichte die Vermutung begründet, Bach habe ein früheres Werk hier für die Hochzeit Stahls umgearbeitet. Somit wird erstmals die Aufführung einer weltlichen Huldigungsmusik Bachs in Berlin nachgewiesen und festgestellt, dass der Anteil solcher Werke im Œuvre Bachs einstmals einen zahlenmäßig weitaus größer gewesen sein müsse.
Vergleiche auch: Heinrich Miesner: Beziehungen zwischen den Familien Stahl und Bach. BJ 1933, S. 71-76
Heinrich Miesner: Graf v. Keyserlingk und Minister v. Happe, zwei Gönner der Familie Bach. BJ 1934, S. 101-115
Über die Schlußchoräle zweier Bachscher Ratswahlkantaten
Authors: Hofmann Klaus 
Published: September 2020

Johann Sebastian Bachs Ratswahlkantaten sind Kirchenmusik, aber zugleich politische Repräsentationskunst. In zwei Kantaten (BWV 119/9 und BWV 120/6) indessen fällt auf, dass die Schlusschoräle im schlichten Kantionalsatz gehalten sind. Satztechnische Details legen die Vermutung nahe, es könnten dazu heute verlorene Pauken- und Trompetenstimmen gegeben haben. (Oliver Schöner, Quelle: Bibliographie des Musikschrifttums online)
Vergleiche auch: Andreas Glöckner: "In Fine Intrada con Trombe e Tamburi". Trompeten und Pauken in den Schlußchorälen von Festkantaten - eine weitere Beobachtung. BJ 2002, S. 201-208
Neumeister versus Dedekind. Das deutsche Rezitativ und die Entstehung der madrigalischen Kantate
Authors: Scheitler Irmgard 
Published: September 2020

Der Artikel diskutiert die widersprüchlichen Standpunkte zur Einführung der madrigalischen Kantate in die Kirchenmusik. Dabei dient besonders Wolfram Steudes These, nicht wie bisher Erdmann Neumeister, sondern Constantin Christian Dedekind als Erfinder dieser Form anzunehmen, als Anstoß einiger grundsätzlicher Überlegungen. Diese widmen sich dem Rezitativvers und seiner Entwicklung, Neumeisters Urteil über Dedekind, Bestimmung und Form der Kantate im theatralischen Stil und dem Verhältnis Bachs zu Neumeisters madrigalischer Kantate.
Erwähnte Artikel:
Elisabeth Noack: Georg Christian Lehms, ein Textdichter Johann Sebastian Bachs. BJ 1970, S. 7-18
Helmut K. Krausse: Erdmann Neumeister und die Kantatentexte Johann Sebastian Bachs. BJ 1986, S. 7-32
Weiterführender Artikel:
Ferdinand Zander: Die Dichter der Kantatentexte Johann Sebastian Bachs. Untersuchungen zu ihrer Bestimmung. BJ 1968, S. 9-64
Laser annealing to improve PbSe thin film photosensitivity and specific detectivity
Authors: Jang Moon-Hyung , Kramer Michael T. , Yoo Sung-Shik , Gupta Mool C. 
Published: September 2020

PbSe thin films were deposited on

S
i
O

2

/

S
i

wafers using chemical bath deposition for mid-wave infrared (MWIR) detection. To enhance the photosensitivity of PbSe thin films, oxidation, followed by iodization, was performed to create a

P
b
I

2

/

P
b
S
e

two-layer system for efficient MWIR detection in the spectral range from 3 µm to 5 µm. A near-infrared (IR) laser annealing was performed after sensitization with 1070 nm wavelength at an energy density of

1

J

/

c
m

2

to selectively heat the PbSe thin films. After IR laser annealing, the change in resistance between dark condition and MWIR illumination improved significantly from 19.8% to 22.6%. In addition, the dark resistance increased by 32.5% after IR laser annealing. IR photoluminescence spectra after IR laser annealing shows an increase in the sub-peak intensities from iodine incorporation. The results indicate that more iodine is incorporated into Se sites at the outer regions of PbSe grains. Therefore, more donors (electrons) from iodine diffuse into PbSe and recombine with holes so that PbSe thin film after IR laser annealing shows much higher dark resistance. Test devices with NiCr electrodes at the bottom of PbSe were fabricated with feature sizes of 40 µm to investigate the effect of IR laser annealing on electrical properties and specific detectivity (

D

∗

). I-V characteristics show dark resistance increased after IR laser annealing. The specific detectivity increases significantly after IR laser annealing at the applied bias of 10 V at 270 K from

0.55
×

10

10

c
m

H

z

1

/

2

W

−
1

to

1.23
×

10

10

c
m

H

z

1

/

2

W

−
1

due to dramatic noise reduction, which is originated from higher dark resistance.
Toward lower-diameter large-scale HPC and data center networks with co-packaged optics
Authors: Maniotis Pavlos , Schares Laurent , Lee Benjamin G. , Taubenblatt Marc A. , Kuchta Daniel M. 
Published: September 2020

We investigate the advantages of using co-packaged optics for building low-diameter, large-scale high-performance computing (HPC) and data center networks. The increased escape bandwidth offered by co-packaged optics can enable high-radix switch implementations of more than 150 switch ports, which can be combined with data rates of up to 400 Gb/s per port. From the network architecture perspective, the key benefits of using co-packaged optics in future fat-tree networks include (a) the ability to implement large-scale topologies of

>

11

,

000

end points by eliminating the need for a third switching layer and (b) the ability to provide up to

4
×

higher bisection bandwidth compared to existing solutions, reducing at the same time the number of required switch application-specific integrated circuits by

>

80

%

. From the network operation perspective, both reduced energy consumption and lower packet delays can be achieved since fewer hops are required; i.e., packets need to traverse fewer serializer/deserializer lanes and fewer switch buffers, which reduces the probability of contending with other packets and improves the tolerance of network congestion. The performance of the proposed architecture is evaluated via discrete-event simulations for a wide range of representative HPC synthetic-traffic cases that include both hotspot and non-hotspot scenarios. The simulation results suggest that co-packaged optics form a promising solution to keep up with bandwidth scaling in future networks, while the reduced number of switching layers can lead to significant mean packet delay improvements that start from 30% and reach up to 74% for high-load conditions.
40  W, 780  nm laser system with compensated dual beam splitters for atom interferometry
Authors: Kim Minjeong , Notermans Remy , Overstreet Chris , Curti Joseph , Asenbaum Peter , Kasevich Mark A. 
Published: September 2020

We demonstrate a narrow-linewidth 780 nm laser system with up to

40

W

power and a frequency modulation bandwidth of 230 MHz. Efficient overlap on nonlinear optical elements combines two pairs of phase-locked frequency components into a single beam. Serrodyne modulation with a high-quality sawtooth waveform is used to perform frequency shifts with

>

96.5
%

efficiency over tens of megahertz. This system enables next-generation atom interferometry by delivering simultaneous, Stark-shift-compensated dual beam splitters while minimizing spontaneous emission.
Penggunaan Peraturan Bupati Untuk Mengatur Harga Tanah Dalam Pengenaan Bea Perolehan Hak Atas Tanah Dan Bangunan
Authors: Ispriyarso Budi 
Published: September 2020

Abstract This study aims to describe the use of regent regulations to regulate land prices in the Imposition of Fees for Acquisition of Land and Building Rights. This research is a normative legal research that uses the regulatory approach. the results showed that the use of District Regulation as a basis for setting land prices in the imposition of BPHTB in Kendal district, was a regulation made for the purpose of legal certainty about land prices, but from the juridical aspects, the regent regulation was not based on the delegation of authority in Kendal district regulation. Regulating BPHTB. Then the estimated price of land as regulated in Kendal Regulation No. 10 of 2017 is based on location criteria, namely Settlements, Agricultural Land, and Housing). And the estimated price of land which is regulated in Kendal Regulation Number 10 of 2017, functions as a comparison. Keywords: Land Prices. BPHTB, Land Tax. Abstrak Penelitian ini bertujuan untuk menguraikan Penggunaan Peraturan Bupati Untuk Mengatur Harga Tanah Dalam Pengenaan Bea Perolehan Hak Atas Tanah Dan Bangunan. Penelitian ini merupakan penelitian hukum normatif yang menggunakan pendekatan peraturan perundang undangan. hasil penelitian menunjukan bahwa Penggunaan Perbup sebagai dasar untuk menetapkan harga tanah dalam pengenaan BPHTB di kabupaten kendal, merupakan peraturan yang dibuat tujuan kepastian hukum tentang harga tanah, namun dari aspek yuridis peraturan bupati tersebut tidak didasarkan pada adanya delegasi kewenangan yang terdapat dalam Perda kabupaten Kendal yang mengatur BPHTB. Kemudian Perkiraan harga tanah yang diatur dalam Perbup Kendal Nomor 10 Tahun 2017 didasarkan pada kriteria lokasi yaitu Pemukiman, Tanah Pertanian dan Perumahan). Dan Perkiraan harga tanah yang diatur Dalam Perbup Kendal Nomor 10 Tahun 2017,berfungsi sebagai pembanding. Kata Kunci: Harga Tanah. BPHTB, Pajak Tanah.
Kelemahan Lembaga Keberatan Pajak
Authors: Ispriyarso Budi 
Published: September 2020

Abstract Tax disputes can occur between taxpayers or tax insurers with the government, among others because of differences in the amount of tax payable. One of the legal efforts that can be taken by taxpayers in the event of a tax dispute is an "Objection" legal effort. This objection is essentially a legal effort that is outside the Tax Court to appeal for justice in a tax dispute. The problem, what weaknesses are there in the objection institutions that exist today. Some of the weaknesses in this tax objection institution include the position within the Directorate General of Taxes or precisely a unit/part that is part of the Tax Service Office (KPP) or the Tax Office. Its position under the Directorate General of Taxation is what has caused criticism from many parties, especially with regard to independence in deciding a case, the Independent is doubtful, there is a conflict of interest. Another disadvantage is the provision that contains a "threat" to taxpayers in filing objections, namely a fine of 50% of the amount of tax payable after deducting the amount of tax paid if the decision rejects the objection filed by the taxpayer or partially grants. Keywords: Objection, tax dispute, the taxpayer Abstrak Sengketa pajak dapat terjadi antara wajib pajak atau penanggung pajak dengan pemerintah , antara lain karena perbedaan penghitungan besarnya pajak yang terutang. Salah satu upaya hukum yang dapat ditempuh wajib pajak dalam hal terjadi sengketa pajak adalah upaya hukum “Keberatan”. Keberatan ini pada hakekatnya merupakan upaya hukum yang berada diluar Pengadilan Pajak untuk memohon keadilan dalam sengketa pajak. Permasalahanya, Kelemahan-kelemahan apa yang terdapat dalam lembaga keberatan yang ada saat ini. Beberapa kelemahan yang terdapat dalam lembaga keberatan pajak ini antara lain adalah kedudukannya yang berada di lingkungan Direktorat Jenderal Pajak atau tepatnya suatu unit/bagian yang merupakan bagian yang ada pada Kantor Pelayanan Pajak (KPP) atau Kanwil Pajak. Kedudukannya yang berada di bawah Direktorat Jenderal Pajak inilah yang menimbulkan kritikan dari banyak pihak khususnya berkaitan dengan keindependenanya dalam memutus suatu perkara, Keindependenanya diragukan, ada conflict of interest. Kelemahan lainnya adalah adanya ketentuan yang mengandung “ancaman” terhadap wajib pajak dalam pengajuan keberatan yaitu adanya denda sebesar 50 % dari jumlah pajak terutang setelah dikurangi jumlah pajak yang telah dibayar, apabila keputusan menolak keberatan yang diajukan wajib pajak atau mengabulkan sebagian. Kata kunci: Keberatan, sengketa pajak, wajib pajak
Politik Hukum Pengakuan Hak atas Administrasi Kependudukan Bagi Penganut Penghayat Kepercayaan
Authors: Sukirno Sukirno 
Published: September 2020

Abstract This article is motivated by the existence of various laws and regulations that discredit and discriminate against believers to get their rights guaranteed by Article 29 paragraph (2) of the 1945 Constitution of the Republic of Indonesia which affirms the right to freedom of religion and belief. The problem raised is what legal politics underlie legislation that prevents trustees from obtaining the same rights as other Indonesian citizens. The search results found that the legal politics underlying the discrediting legislation and discriminating against religious believers were the legal politics of the world religions paradigm which gave the majority the religious role to intervene in government policies to marginalize religious minorities. Keywords: legal politics, belief groups. Abstrak Artikel ini dilatar belakangi adanya berbagai peraturan perundang-undangan yang mendiskreditkan dan mendiskriminasi penghayat kepercayaan untuk mendapatkan hak-haknya yang sudah dijamin oleh Pasal 29 ayat (2) UUD NRI 1945 yang menegaskan hak kebebasan beragama dan berkepercayaan. Permasalahan yang diangkat adalah politik hukum apa yang melandasi peraturan perundang-undangan yang menghalangi penghayat kepercayaan untuk memperoleh hak-hak yang sama sebagaimana warga negara Indonesia lainnya. Hasil penelusuran menemukan bahwa politik hukum yang melandasi peraturan perundang-undangan yang mendiskreditkan dan mendiskriminasi penghayat kepercayaan adalah politik hukum paradigma agama dunia yang memberikan peran agama mayoritas untuk mengintervensi kebijakan pemerintah untuk meminggirkan agama minoritas atau kepercayaan. Kata kunci: Politik Hukum, Penghayat Kepercayaan.
Diskresi Dalam Rekrutmen Pegawai Non Pegawai Negeri Sipil Setelah Pemberlakuan Peraturan Pemerintah Nomor 49 Tahun 2018 tentang Manajemen Pegawai Pemerintah Dengan Perjanjian Kerja
Authors: Juliani Henny 
Published: September 2020

Abstrak This research was conducted to find out legal consequencies as a result of discretion made by Government Officers in recruiting contract-based employees after Government Regulation Number 49 of 2018 concerning Management of Contract-based Public Servants (Manajemen PPPK). This research was conducted by using normative juridical method and analytical descritive approach. There is regulation regarding prohibition to recruit contract-based employees to fulfill lack of public servants position in government institutions. Hence, discretion cannot be used to comply manpower need, but still can be done through formation proposal of public servants and/or contract-based employees. Contract-based employees still have to conduct their job for maximum 5 years and have opportunity to be recruited as non-organic employees (non-organic public servants) as long as the employees comply conditions stated in Government Regulation Number 49 of 2019. Keywords: Discretion of Government Officers, Non-Organic Public Servants Abstrak Penelitian ini dilakukan untuk mengetahui akibat hukum yang timbul dari diskresi Pejabat Pemerintahan dalam perekrutan pegawai tidak tetap/non-PNS (honorer/kontrak) setelah berlakunya PP Nomor 49 Tahun 2018 tentang Manajemen PPPK. Metode pendekatan yang digunakan adalah yuridis normatif, spesifikasi penelitian yang digunakan adalah deskriptif analitis. Terdapat ketentuan tentang larangan perekrutan Pegawai tidak tetap/non-PNS untuk mengisi jabatan ASN di instansi pemerintahan. Oleh karena itu diskresi tidak dapat lagi digunakan untuk memenuhi kebutuhan pegawai, namun dapat dilakukan melalui usul formasi CPNS dan/atau PPPK. Pegawai tidak tetap/non-PNS masih tetap melaksanakan tugas paling lama 5 (lima) tahun dan dapat diangkat menjadi PPPK apabila memenuhi persyaratan yang diatur dalam PP Nomor 49 Tahun 2018. Kata Kunci: Diskresi Pejabat Pemerintahan, Pegawai non-PNS
Asas-Asas Umum Pemerintahan yang Baik dalam Pelayanan Publik
Authors: Solechan Solechan 
Published: September 2020

Abstract AAUPB (Asas asas umum pemerintahan yang Baik) has a long journey from the beginning of its birth in the Netherlands to its application in Indonesia today. AAUPB at first was only in the theoretical realm and then entered into law until AAUPB got a very important position in Law No. 30 of 2014. Initially, AAUPB was intended as a means of legal protection or rechtsbescherming and was even used as an instrument to increase legal protection or rechtsbescherming for citizens from government actions. AAUPB is then used as the basis for judgments in the judiciary and administrative efforts, as well as an unwritten legal norm for government actions The history of the development of AUPB in Indonesia can be seen from the development of the AUPB principle in various laws and regulations, the practice of implementing the AUPB in court decisions or jurisprudence and doctrine. The development of the AUPB principle arrangement had found an increasingly strong momentum when the Government Administration Act was passed in 2014. As a result of the adoption of the concept of the welfare state, the state must fulfill the welfare of the community, one of which is through public services. With the AAUPB, it is expected that the government as a public service provider, can accept the AAUPB as a legal norm that must be used as the basis by the civil service provider in carrying out its authority, as well as a means for citizens to sue deviant public service providers. Keywords: General principles of good governance, public service. Abstrak Asas-asas umum pemerintahan yang baik (selanjutnya disebut AAUPB) lahir dari praktik penyelenggaraan negara dan pemerintahan sehingga bukan produk formal suatu lembaga negara seperti undang-undang. Asas-asas umum pemerintahan yang baik dapat dipahami sebagai asas-asas umum yang dijadikan sebagai dasar dan tata cara dalam penyelenggaraan pemerintahan yang layak, yang dengan cara demikian penyelenggaraan pemerintahan itu menjadi baik, sopan, adil, dan terhormat, bebas dari kezaliman, pelanggaran peraturan, tindakan penyalahgunaan wewenang dan tindakan sewenang-wenang. Sejarah perkembangan AUPB di Indonesia dapat dilihat dari perkembangan prinsip AUPB dalam berbagai peraturan perundang-undangan, praktik penerapan AUPB dalam putusan pengadilan atau yurisprudensi serta doktrin. Perkembangan pengaturan prinsip AUPB menemukan momentumnya yang semakin kuat, tatkala UU Administrasi Pemerintahan disahkan pada tahun 2014. Sebagai akibat dari dianutnya konsepsi welfare state maka negara memiliki kewajiban untuk memenuhi kesejahteraan masyarakat salah satunya melalui pelayanan publik. Dengan adanya AAUPB diharapkan pemerintah sebagai pemberi pelayanan publik dapat menerima AAUPB sebagai norma hukum yang harus dijadikan dasar oleh penyelenggara pelayanan publik dalam menjalankan kewenangannya, sekaligus sarana bagi warga negara untuk menggugat penyelenggara pelayanan publik yang menyimpang. Kata Kunci : Asas-asas umum pemerintahan yang baik, Pelayanan Publik