bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interview with the Inventor of the Future Network IPV9
Authors: Chen Guoshao , Wang Yubian 
Published: October 2020

Abstract
With the rapid development of the Internet, from the PC terminal to the mobile terminal, from big data systems to intelligent hardware, technology has shown the unique charm of the Internet. With the development of the Internet, the network information security and network sovereignty issues involved have become increasingly prominent. Therefore, only in an environment of security, equality, and mutual assistance can the Internet play its due economic and social value. The emergence of a new generation of Internet IPV9 marks a key step for China to move towards an autonomous and controllable future network. IPV9 is to further safeguard national network sovereignty on the basis of fully guaranteeing network information security. But the defamation of IPV9 still exists. Recently, in order to further clarify the facts, we hereby interviewed Xie Jianping, the inventor of the Decimal Network, to conduct an in-depth discussion on the new generation Internet IPV9.
Caracterización sensorial y percepción del nuevo consumidor de feijoa (Acca sellowiana (Berg) Burret)
Authors: Matías Jesús Alberto Nolasco , Montes Arturo Hernández , Medel Roberto Rendón , Cruz Castillo Juan Guillermo 
Published: October 2020

Introducción: El fruto de la feijoa ha cobrado relevancia internacional debido a sus altas propiedades nutraceúticas. En contraste con Nueva Zelanda, Colombia o Turquía, en México, su cultivo es incipiente y hasta el momento se produce solamente en los estados de México, Michoacán, Puebla y Veracruz. Un problema que existe en México para la venta de este fruto es su baja comercialización. Así, estudiar las variables que influyen en el proceso de decisión de compra es relevante. El objetivo del presente estudio fue caracterizar algunos atributos sensoriales del nuevo consumidor de feijoa fresca, así como el grado de afectividad que tienen por esta fruta.Método: Las características sensoriales de la feijoa (Acca sellowiana), carambola (Averrhoa carambola), kiwi (Actinidia chinensis) y guayaba (Psidium guajava) fueron analizadas. Con el perfil sensorial de estos frutos, se realizó un análisis descriptivo cuantitativo (ADC), y posteriormente se llevó a cabo una prueba de aceptabilidad que determinó la afectividad de los consumidores sobre determinados atributos sensoriales del fruto. También, se realizó una prueba de preferencia afectiva por pares entre la feijoa y la guayaba. Resultados y discusión: los atributos sensoriales que caracterizaron a la feijoa fueron su aroma dulce, intensidad de aroma y sabor residual frutal; la carambola sobresalió en jugosidad; la guayaba en intensidad de aroma y acidez; y el kiwi en acidez y homogeneidad. De las cuatro frutas comparadas, la feijoa presentó los valores más altos en acidez, aroma dulce, intensidad de aroma, homogeneidad, dureza y sabor residual frutal. En cuanto a aceptabilidad global, la guayaba, el kiwi y la feijoa fueron las más gustadas por los consumidores.Conclusión: La feijoa mostró superioridad en la mayoría de los atributos sensoriales. El aroma dulce y la intensidad del aroma favorecieron su aceptación con respecto al kiwi, carambola y guayaba. En contraste, su jugosidad, pegajosidad, y acidez tuvieron valores que afectaron negativamente su aceptabilidad. La guayaba fue aceptada mientras tenga menor acidez. El kiwi tuvo atributos como pegajosidad y bajo sabor residual frutal aceptados favorablemente. La carambola tuvo la menor aceptación debido a la alta acidez, sin embargo, tuvo atributos como homogeneidad y jugosidad que gustaron a los consumidores.
Znaczenie tomografii komputerowej w diagnostyce nowotworów wątroby
Authors: Głodek Aleksandra Monika 
Published: October 2020

Badania obrazowe są integralną częścią diagnostyki chorób nowotworowych. Do badań tych zalicza się między innymi: ultrasonografię (USG), tomografię komputerową (TK) oraz rezonans magnetyczny (MRJ). Wykonanie ultrasonografii jest stosunkowo proste i tanie. W oparciu o przeprowadzone badanie USG, radiolog zazwyczaj jest w stanie ocenić wielkość wątroby, echogeniczność, czy obecność struktur patologicznych w jej obrębie. W celu uzyskania bardziej szczegółowej wiedzy na temat zmiany, pacjentom zaleca się badanie tomograficzne lub badanie rezonansem magnetycznym z użyciem środka kontrastowego. TK wykorzystuje promieniowanie jonizujące, dzięki czemu powinna być zlecana według ściśle określonych wskazań. W trakcie jednego badania wykonuje się wiele zdjęć rentgenowskich, co istotnie wpływa na dawkę zaabsorbowaną w ciągu roku przez pacjenta. Nowotwory wątroby stanowią 7% wszystkich nowotworów. Do czynników zwiększających ryzyko zachorowania na nowotwór wątroby zalicza się między innymi marskość wątroby, zakażenie wirusem B lub C, a także nadużywanie alkoholu. Badanie TK pozwala na zdefiniowanie charakteru zmiany, a także jest pomocne w określeniu jej zasięgu. Procedura ta umożliwia opisanie stosunku guza do struktur położonych w pobliżu. MRJ może być alternatywą w przypadku braku uzyskania satysfakcjonującej wiedzy na temat nowotworu w badaniach poprzednich.
Spatial-temporal trends analysis of flood events in the Republic of Armenia in the context of climate change
Authors: Galstyan Hrachuhi , Khan Shamshad , Sayadyan Hovik , Sargsyan Artur , Safaryan Tatevik 
Published: October 2020

Abstract
The primary goal of the study is to analyze the spatial-temporal trends and distribution of flood events in the context of climate change in Armenia. For that purpose, some meteorological parameters, physical-geographical factors and the flood events data were studied for the 1994–2019 period. The linear trends demonstrate an increasing tendency of air temperature and precipitation. Those trends expressed increased flood occurrences, especially for the 2000s, whereas the Mann–Kendall (MK) trend test reveals no significant change. The number of flood events reaches its maximum in 2011 with its peak in May. Out of 191 flood events, half of the occurrences are recorded in the flat areas and southern aspects of the mountains (22% of the country's territory). There is a certain clustering of flood events in the areas with up to 5° slopes (66% of flood events). The most flood vulnerable areas were analyzed and mapped via Geographical Information System (GIS). The GIS-based mapping shows the location of flood vulnerable areas in the central, northern parts of the country, and the coastal areas of Lake Sevan. Our methodological approach elaborates the localization of flood-prone sites. It can be used for the flood hazard assessment mapping and risk management.
Risk Factors Associated with Acute Appendicitis in Pregnancy
Authors: Ahmadinejad Mojtaba , Hashemi Seyed Mozaffar , Jamee Mahnaz 
Published: October 2020

Backgrounds::
Acute appendicitis has been considered as the most common non-obstetric
indication that requires surgical intervention in pregnant women.

Objective:
The aim of this study is to compare clinical manifestations and para-clinical indices
between pregnant and non-pregnant patients who have undergone appendectomy.

Methods::
In this prospective cohort study, 57 pregnant and non-pregnant women presenting appendicitis
were compared in terms of diagnostic indicators, histopathological characteristics and laboratory
findings.

Results::
Periumbilical region was the point of initiation of the pain; however, it was more prominent
in non-pregnant women. Similarly, tenderness in RLQ (right lower quadrant) of the abdomen
was more detectable in the non-pregnant group, and some of the cases showed no rebound tenderness.
Pregnant women with appendicitis presented an abnormal increase in the WBC count.

Conclusion::
Pregnancy and appendicitis-related signs and symptoms have similarity among them.
Due to pregnancy, the physical examination might not present an exact diagnosis; therefore, pregnant
women susceptible to have appendicitis must undergo a complete and careful on-time examination
that includes ultrasound and labs.
Discovery and Design of Peptides as MMP9 Inhibitors through Structure-Based Molecular Docking for Targeted Mantle Cell Lymphoma Therapy
Authors: Yan Wei , Yang Ying , Yang Wei , Wei Minjie 
Published: October 2020

Background:
Enhanced expression and activation of metalloproteinase-9 (MMP9) are associated with
Mantle Cell Lymphoma (MCL) progression, invasion and metastasis.

Objective:
To find a potential peptide inhibitor against MMP9, which, in turn, could inhibit MCL progression.

Methods:
We performed CCK8 assay, western blot, and transwell assays for RNAi activity. Molecular Operating
Environment (MOE) software was applied for structural optimization as MMP9 and peptides were docked. We
used gelatin zymography and confocal microscopy to confirm that the peptides can inhibit MMP9 activity. We
applied CCK8 and transwell assay to evaluate cell proliferation and metastasis, and flow cytometry to evaluate
cell cycle progression and apoptosis.

Results:
High MMP9 expression was observed in 49 of 88 samples (55.7%). Patients with high MMP9
expression were more likely to present with high stage (Stage 3-4, P=0.01), bone marrow invasion (P=0.033),
and high-level LDH (P=0.000). High MMP9 expression was associated with significantly shorter overall survival
(OS, HR=2.378, P=0.012) and progression-free survival (PFS, HR=2.068, P=0.03). Multivariate analysis
identified high MMP9 expression (P= 0.027), high-risk mantle cell lymphoma international prognostic index
(MIPI, HR=2.327, P=0.023), and no radiation therapy (P=0.035) as adverse prognostic factors. The silencing of
MMP9 in Jeko-1 cells by RNAi suppressed cells migration and invasion in vitro (P<0.05). According to the
docking results, peptide M3 bound deeply in the binding pocket of MMP9 and had interaction with the active-site
Zn2+ ion in the catalytic domain. M3 was not only compatible with MMP9, but also inhibited its activity. M3
inhibited Jeko-1 cells proliferation, metastasis, and cell cycle progression, and promoted cell apoptosis rate
(P<0.05).

Conclusion:
We designed M3 through structure-based molecular docking, which can specifically bind to MMP9
and inhibit the activity of MMP9. M3 could be a potential antagonist in the treatment of MCL with MMP9
overexpression.
Mental and Emotional Wellbeing During the COVID-19 Pandemic: The Unprecedented Malaysian Experience
Authors: Mahmud Zamalia , Rahim Rosli Abdul , Abidin Aida Wati Zainan , Abdullah Nik Nairan Nik 
Published: October 2020

Background:
The Movement Control Order (MCO) due to COVID-19 has brought people’s
life to almost a standstill. How people across different ages and income groups are mentally and
physically adjusting to the unprecedented situation in Malaysia is yet to be documented. Hence, an
empirical study was conducted to capture this real-time situation during COVID-19 MCO.

Objective:
To describe the mental and emotional wellbeing of Malaysians and how they care for themselves
and their family during the COVID-19 pandemic and during MCO.

Methods:
A survey on 3,288 respondents was conducted towards the end of the first phase of MCO.
The questionnaire was administered through various online social media platforms using snowball and
convenience sampling.

Results:
About 90% of the respondents gave their priority to health needs and in providing food, shelter
and clothing for their family, while education is at the bottom of their priority list. The overall index
of mental wellbeing and emotional stability went beyond 57% up to 95%, indicating that people
are mentally and emotionally disturbed with COVID-19. The index ranges between 49% up until 90%
in the ability to care for themselves and family.

Conclusion:
Health needs were at the top of the priority list of the high income group and least in the
low income group. While for the low income group, the top most priority concerns their financial stability.
Education was given the least priority by all income groups. Their greatest fear is the infection
of COVID-19 that would harm their family’s health. They were also stressed with the COVID-19 pandemic
that could affect the Malaysian economy and thus worried about losing their sources of income
if this pandemic prolongs over an indefinite period.
The value placed on roles and attributes of clinical educators: An international comparison of Indian, South African and Australian undergraduate physiotherapy students.
Authors: Milanese Steve , Gordon Susan , Swaminathan Narasimman 
Published: October 2020

Aim and Background: Clinical Education opportunities for undergraduate Physiotherapy students are now increasingly occurring internationally. The clinical educator (CE) plays a significant role in the clinical education process particularly when a student undertakes a clinical placement in a different country as the CE often takes on a surrogate caretaker role. This study explores the self-reported perceptions of Physiotherapy students from three countries representing different global society clusters – South Africa (Sub-Saharan Africa), India (Southern Asia) and Australia (Anglo), regarding the roles and attributes of a CE that they value in the clinical education process.
Method: Data was collected from undergraduate Physiotherapy students in a university in India (n=23) and Australia (n=154) and compared with data from a similar student cohort in South Africa (n=70). Students were asked roles and attributes of a clinical educator were of most value in the clinical education setting.
Results: The relative values placed on CE roles/attributes across the three cohorts was similar, however specific differences between cohorts suggest that clinical educators should be aware of differences when supervising international students.
ALETHIC PLURALISM AND TRUTH-ATTRIBUTIONS
Authors: Wrenn Chase 
Published: October 2020

Abstract
The core of alethic pluralism is the idea that truth is a different property in some discourses from others. Orthodox pluralists such as Crispin Wright and Michael Lynch share three commitments that motivate their view. One is Ecumenicalism, the view that scientific and moral claims are both truth-apt. The second is Occasional Realism, the view that truth in science is a matter of justificationindependent, accurate representation, while truth in ethics is a matter of ideal epistemic justifiability. The third is Normativism, the view that truth-attributions are normative in a way deflationary theories cannot accommodate. This paper articulates the “aletheiological dilemma” for orthodox pluralists. The dilemma arises when we ask whether the truth-property relevant to truth-attributions is epistemic. Occasional Realism requires it not be, but Normativism and the pluralists’ other commitments require truth for truth-attributions to be a matter of ideal justifiability. The paper also considers some ways around the dilemma, none of which looks very promising for pluralists.
THE FORCE OF ALETHIC PLURALISM
Authors: Strollo Andrea 
Published: October 2020

AbstractBelief, according to many philosophers, aims at truth. In this paper I discuss in what measure a pluralist conception of truth is compatible with this claim. In particular, I argue that if the idea is understood according to a teleological account, alethic pluralism can be adopted also in a strong form. I contend that while the teleological account of belief requires a generic concept of truth, it poses a few constraints on the property (or the properties) of truth. By contrast, at least a moderate version of alethic pluralism is commanded by a normativist interpretation of the aim.
Political Patronage, Audit Quality, and the Properties of Analysts' Earnings Forecasts in Malaysia
Authors: Gist Willie E. , Abdul Wahab Effiezal Aswadi 
Published: October 2020

ABSTRACT
Based on a sample of 2,034 Malaysian listed firm-year observations for the period 2007–2014, this study shows a negative relationship between dimensions of political patronage (i.e., politically connected firms and the percentage of Bumiputera directors) and analysts' earnings forecast accuracy. Furthermore, the study documents a positive relationship between Bumiputera directors and earnings forecast dispersion. These results suggest that the political patronage of firms is associated with low-quality earnings. We also find that measures of high audit quality are associated with high financial reporting quality and that this is evident in firms with high audit quality showing a weaker negative (positive) relationship between forecast accuracy (dispersion) and political connections and high levels of Bumiputera directors. Overall, the findings suggest that high audit quality plays an important role in mitigating agency costs of information asymmetry by improving the financial information environment.
JEL Classifications: G24; G34; G38.
Immune Checkpoint Inhibitor–Associated Diabetes: A Single-Institution Experience
Authors: Byun David J. , Braunstein Rebecca , Flynn Jessica , Zheng Junting , Lefkowitz Robert A. , Kanbour Sarah , Girotra Monica 
Published: October 2020

OBJECTIVE
To characterize immune checkpoint inhibitor–associated diabetes mellitus (ICI-DM) in a single-institution case series.

RESEARCH DESIGN AND METHODS
Retrospective chart review of 18 patients with new-onset ICI-DM following anti–programmed cell death protein 1 (PD-1)/anti–programmed cell death protein ligand 1 (PD-L1) therapy for advanced carcinomas.

RESULTS
Of 18 patients, 9 had diabetic ketoacidosis (median glucose 27.92 mmol/L; median glucose before presentation 6.35 mmol/L). Median C-peptide at ICI-DM diagnosis was low, and it declined during follow-up. Median anti-PD-1/anti-PD-L1 duration before ICI-DM was 3.65 months (range 0.56–12.23 months). Time to ICI-DM onset was a median 1.4 months/3 ICI cycles and 6 months/10 cycles in those patients who were positive and negative for GAD65 autoantibodies, respectively. Time to ICI-DM onset was a median 2.5 months/3 ICI cycles and 4.8 months/8 cycles after anti-PD-L1 or anti-PD-1 therapy, respectively. Significant pancreatic atrophy was seen radiographically.

CONCLUSIONS
ICI-DM presents abruptly, appears irreversible, is characterized by pancreatic atrophy, and may occur both earlier following PD-L1 blockade compared with PD-1 inhibition and in those who have positive GAD65 autoantibodies.
LOGÍSTICA EM EVENTO: ESTUDO DE CASO DE UMA COMISSÃO DE FORMATURA LOCALIZADA NO INTERIOR DO SUL DE MINAS GERAIS
Authors: Ferreira Leticia Silva , Andrade Daniela Meirelles , Vieira Luciana Dos Santos , Gonçalves Vinicius Batista 
Published: October 2020

Esta pesquisa tem como objetivo identificar e descrever as atividades logísticas necessárias para a realização do mesmo. Além disso, pretende detectar as possíveis falhas e propor melhorias para que o nível de serviço prestado não seja comprometido. A organização do baile envolve quatro fases, quais sejam: concepção – levantamento de informações; pré-evento – planejamento e organização; transevento – execução; pós-evento – desmontagem e avaliação. Em termos metodológicos, trata-se de um estudo de caso de abordagem quantitativo e qualitativo. Para a coleta dos dados, foram realizadas entrevistas semiestruturadas, observação participante e aplicação de questionário de avaliação pós-evento com a finalidade de obter a percepção e satisfação do cliente. Na fase do pré-evento, existe um envolvimento maior dos organizadores em todo o planejamento do evento. Na execução do evento, é feita a conferência das atividades por meio do instrumento de controle checklist. Já no pós-evento, além da descrição das atividades de desmontagem, foi feita a avaliação por meio do questionário de satisfação do cliente. Conclui-se que o nível de serviço foi alcançado, mas existem algumas falhas a serem sanadas para os futuros eventos.
TEACHER QUESTIONING IN CLASSROOM INTERACTION
Authors: Matra Sarlita Dewi 
Published: October 2020

Questions play an important role in every classroomboth
students questions and teachers questions. The types of
question used by teacher can help students to lift their own
levels of understanding toward the concept given or even to
build up new ideas. The study explored (1) how eventually
teachers provide some ease to the students in creating an
interactive classroom interaction through questions and
answers exchanges; (2) how the questioning technique used by
the teachers might encourage the students to be active in
classroom interaction. By using Browns Interaction Analysis
System (BIAS) the data were analyzed in order to find out what
types of question were mostly used by the teachers during
teaching learning process in encouraging the students
activeness. The data were collected through observations in two
English classes in SMP N 2 Pekalongan with two different
English teachers. The data showed that the cognitive level of
teachers questions which mostly occurred was lower order
cognitive questions. The questions were aimed to invite the
learners to speak and deliver their ideas. Based on the observed
data, in details, the result showed that teachers used recall
questions for 52%, comprehension for 42% and application
occupied the remaining that was 6%. The target language was
usually used on several occasions such as praising, encouraging,
explaining and giving directions during the classroom
interaction. Therefore, the suggestions are given to the teacher
to understand practical uses of questioning techniques in
minimizingstudents barriers to speak up in English.
Phenotypic and genetic properties of susceptible and multidrug-resistant Pseudomonas aeruginosa isolates in Southern Serbia
Authors: Milojković Marko , Nenadović Željka , Stanković Slaviša , Božić Dragana D. , Nedeljković Nataša Stanković , Ćirković Ivana , Petrović Marija , Dimkić Ivica 
Published: October 2020

Abstract
Drug resistance of Pseudomonas aeruginosa is a leading problem in hospital infections. The aim of this study was to determine the best molecular genetic discrimination method for Pseudomonas spp. isolates among 94 outpatients and inpatients and see their grouping by phenotype characteristics (biofilm formation, frequency of serotypes, pigmentation, production of different class of beta-lactamases, and susceptibility to different antibiotic classes) and genotype. The most common serotypes were P1, P6, and P11, while co-productions of pyoverdine and pyocyanin were observed in 70 % of isolates. A total of 77.66 % isolates were mostly weak and moderate biofilm producers. Isolates were susceptible to colistin (100 %), aztreonam (97.87 %), imipenem (91.49 %), doripenem (90.43 %), and meropenem (84.04 %). MICs values confirmed susceptibility to ceftazidime and cefepime and singled out meripenem as the most effective inhibitor. Most isolates were resistant to aminoglycosides and fluoroquinolones. Only two isolates produced ESBL, eight were carbapenemase producers, and five isolates produced MBLs. Twenty-nine isolates were multidrug-resistant; 82.8 % of which produced both pigments, 58.3 % were non-typeable, while the P6 and P11 serotypes were equally distributed (16.7 %). Thirteen MDR isolates were strong enzyme producers. RAPD PCR analysis using primer 272 proved the best at discriminatory fingerprinting for Pseudomonas isolates, as it allocated 12 clusters. A correlation between DNA patterns and antibiotic resistance, production of pigments, serotypes distribution, and biofilm formation was not observed, and only confirmed higher genetic heterogeneity among P. aeruginosa isolates, which suggests that other molecular methods are needed to reveal potential relations between genotypic patterns and phenotypic characteristics.