bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel application of deep learning with image cropping: a smart city use case for flood monitoring
Authors: Mishra Bhupesh Kumar , Thakker Dhavalkumar , Mazumdar Suvodeep , Neagu Daniel , Gheorghe Marian , Simpson Sydney 
Published: February 2020

AbstractEvent monitoring is an essential application of Smart City platforms. Real-time monitoring of gully and drainage blockage is an important part of flood monitoring applications. Building viable IoT sensors for detecting blockage is a complex task due to the limitations of deploying such sensors in situ. Image classification with deep learning is a potential alternative solution. However, there are no image datasets of gullies and drainages. We were faced with such challenges as part of developing a flood monitoring application in a European Union-funded project. To address these issues, we propose a novel image classification approach based on deep learning with an IoT-enabled camera to monitor gullies and drainages. This approach utilises deep learning to develop an effective image classification model to classify blockage images into different class labels based on the severity. In order to handle the complexity of video-based images, and subsequent poor classification accuracy of the model, we have carried out experiments with the removal of image edges by applying image cropping. The process of cropping in our proposed experimentation is aimed to concentrate only on the regions of interest within images, hence leaving out some proportion of image edges. An image dataset from crowd-sourced publicly accessible images has been curated to train and test the proposed model. For validation, model accuracies were compared considering model with and without image cropping. The cropping-based image classification showed improvement in the classification accuracy. This paper outlines the lessons from our experimentation that have a wider impact on many similar use cases involving IoT-based cameras as part of smart city event monitoring platforms.
Identification of a norovirus outbreak on a hematopoietic stem cell transplant unit and development and implementation of a novel infection prevention algorithm for controlling transmission
Authors: Branch-Elliman Westyn , Araujo-Castillo Roger V. , Snyder Graham M. , Sullivan Bernadette F. , Alonso Carolyn D. , Wright Sharon B. 
Published: February 2020

ABSTRACTControlling norovirus transmission in units with immunocompromised patients is challenging. We present a cluster of norovirus cases that occurred on a stem-cell transplant unit and the prevention efforts that were implemented to limit the outbreak. Protocols developed to control this cluster may provide a model for other facilities.
Association of e-cigarette use and smoking cessation among Canadian young adult smokers: secondary analysis of data from a randomised controlled trial
Authors: Saxena Arti , Baskerville Neill Bruce , Garcia John M. 
Published: February 2020

AbstractAimsThis study examined the reasons for e-cigarette (EC) use, changes in self-efficacy and association between EC use and cessation of tobacco among Canadian young adult smokers over a 6-month period.MethodsA secondary analysis was conducted using data from a randomised controlled trial (RCT) of young adult Canadian smokers. EC exposure was defined as persistent, transient and non-use of ECs at baseline and follow-up. The association between EC exposure and cessation was examined using logistic regression and adjusting for co-variates.ResultsAt 6-month follow-up, persistent EC use was associated with a lower cessation rate (13%) than transient (23%) or non-use (29%). After adjusting for covariates, non-use and transient use were associated with higher odds of cessation than persistent use (AOR = 3.23, 95% CI = 1.41–7.40, P < 0.01; AOR = 2.40, 95% CI = 1.01–5.58, P < 0.05). At 6-month follow-up, persistent users (68%) had high self-efficacy as compared to transient (15%) or non-use (12%). Top reasons for EC use included use as a quit aid (67%), perceived use as less harmful (52%) and taste (32%).ConclusionsAmong young adult Canadian smokers enrolled in a RCT of a cessation intervention, persistent and transient use of ECs was associated with a lower smoking cessation rate at 6 months.
Evolution of mobile phases in cometary interiors
Authors: Fellows Christopher M. , Brown Trevor C. , Cooper Andrew , Parigi Marco 
Published: February 2020

Abstract
Beginning with loose aggregations of dust particles coated with heterogeneous ices under vacuum at Kuiper Belt temperatures, moving to Jupiter/Saturn distances and eventually to low-perihelion orbit, we consider the likely development of the gaseous phase within a cometary nucleus over the course of its lifetime. From the perspective of physical chemistry, we consider limits on the spatial and temporal distribution and composition of this gaseous phase. The implications of the gaseous phase for heat transfer and for the possible spatial and temporal development of liquid phases are calculated. We conclude that the likely temperatures, pressures, and compositions beneath the outer crust of typical cometary nuclei are such that fluidised phases can exist at significant depths and that these reservoirs give a coherent explanation for the high-intensity outbursts observed from cometary nuclei at large distances from perihelion.
Rare sapphire-bearing syenitoid pegmatites and associated granitoids of the Hamedan region, Sanandaj–Sirjan zone, Iran: analysis of petrology, lithogeochemistry and zircon geochronology / trace element geochemistry
Authors: Sepahi Ali A , Vahidpour Hamed , Lentz David R , McFarlane Chris RM , Maanijou Mohammad , Salami Sedigheh , Miri Mirmohammad , Mansouri Mehrak , Mohammadi Razieh 
Published: February 2020

AbstractPegmatites and associated granitoids are integral parts of the Alvand plutonic complex in the Sanandaj–Sirjan zone, Iran. Whole rock major- and trace-element lithogeochemistry together with zircon U–Pb geochronology and zircon geochemistry are examined to evaluate the petrogenesis of sapphire-bearing pegmatites and other peraluminous pegmatites in the region. Pegmatites vary in their chemical compositions from mostly peraluminous, high-K calc-alkaline to shoshonitic signatures. A rare variety of extremely peraluminous sapphire-bearing syenitoid pegmatite (Al2O3> 30 wt %; A/CNK > 2) exists. This silica-undersaturated pegmatite and its sapphire crystals have a primary igneous origin. U–Pb zircon geochronology of three separate samples from this pegmatite indicates the following ages: 168 ± 1 Ma, 166 ± 1 Ma and 164 ± 1 Ma. The zircon grains have notable amounts of Hf (up to 17 200 ppm), U (up to 13 580 ppm), Th (up to 5148 ppm), Y (up to 4764 ppm) and ∑REE (up to 2534 ppm). There is a positive correlation between Hf and Th, Nb and Ta, U and Th, and Y and HREE and a negative correlation between Hf and Y values in the zircons. These zircons exhibit pronounced positive Ce anomalies (Ce/Ce* = 1.15–68.06) and negative Eu anomalies (Eu/Eu* = 0.001–0.56), indicative of the relatively oxidized conditions of the parent magma. Ti-in-zircon thermometry reveals temperatures from as low as ~683 °C up to ~828 °C (average = 755° ± 73 °C). Zircon and monazite saturation equilibria are also consistent with these temperatures. Zircon grains are magmatic (average La < 1.5, (Sm/La)N> 100 and Th/U > 0.7), with chemical characteristics similar to zircons from continental crust.
Personal and Clinical Factors Associated with Older Drivers’ Self-Awareness of Driving Performance
Authors: Chen Yu-Ting , Gélinas Isabelle , Mazer Barbara , Myers Anita , Vrkljan Brenda , Koppel Sjaan , Charlton Judith L. , Marshall Shawn C. 
Published: February 2020

ABSTRACTMost older adults perceive themselves as good drivers; however, their perception may not be accurate, and could negatively affect their driving safety. This study examined the accuracy of older drivers’ self-awareness of driving ability in their everyday driving environment by determining the concordance between the perceived (assessed by the Perceived Driving Ability [PDA] questionnaire) and actual (assessed by electronic Driving Observation Schedule [eDOS]) driving performance. One hundred and eight older drivers (male: 67.6%; age: mean = 80.6 years, standard deviation [SD] = 4.9 years) who participated in the study were classified into three groups: underestimation (19%), accurate estimation (29%), and overestimation (53%). Using the demographic and clinical functioning information collected in the Candrive annual assessments, an ordinal regression showed that two factors were related to the accuracy of self-awareness: older drivers with better visuo-motor processing speed measured by the Trail Making Test (TMT)-A and fewer self-reported comorbid conditions tended to overestimate their driving ability, and vice versa.
Examining income dynamics and externalizing and internalizing trajectories through a developmental psychopathology lens: A nationally representative study
Authors: Miller Portia , Betancur Laura , Whitfield Kendra , Votruba-Drzal Elizabeth 
Published: February 2020

AbstractPrior research has documented elevations in levels of internalizing and externalizing behaviors among children in lower income families in comparison to more advantaged peers. However, most studies focus on behavior problems at a single point in time or within a short developmental period. Associations between income dynamics and developmental trajectories of behavior problems over time are less understood. To address this, the current study uses data from the National Longitudinal Study of Youth (N= 7,476; 50.8% male) to examine how income dynamics (annual income and income volatility) across three distinct developmental periods from early childhood to early adolescence relate to trajectories of externalizing and internalizing problems. Group-based mixture modeling revealed a five-group trajectory model for externalizing behavior and a four-group trajectory model for internalizing behavior. Higher cumulative annual income predicted greater likelihood of belonging to the low-stable group compared to the other, more problematic groups for both externalizing and internalizing trajectories. In addition, income losses predicted higher risk of membership in any group other than the low-stable group for internalizing and externalizing behavior. Developmental period-specific income dynamics, though not as consistent as cumulative dynamics, also predicted trajectory group membership.
Long-term dietary flavonoid intake and change in cognitive function in the Framingham Offspring cohort
Authors: Shishtar Esra , Rogers Gail T , Blumberg Jeffrey B , Au Rhoda , Jacques Paul F 
Published: February 2020

AbstractObjective:To examine the association between long-term intake of total and the six classes of dietary flavonoids and decline in cognitive function over a follow-up period of up to 15 years.Design:In this longitudinal study, we evaluated change in eight cognitive domain scores (verbal and visual memory, verbal learning, attention and concentration, abstract reasoning, language, visuoperceptual organisation and the global function) based on three neuropsychological exams and characterised the annualised change between consecutive exams. Long-term intakes of total and six flavonoid classes were assessed up to four times by a validated FFQ. Repeated-measures regression models were used to examine the longitudinal association between total and six flavonoid classes and annualised change in the eight cognitive domains.Setting:The Framingham Heart Study (FHS), a prospective cohort study.Participants:One thousand seven hundred and seventy-nine subjects who were free of dementia, aged ≥45 years and had attended at least two of the last three FHS Offspring cohort study exams.Results:Over a median follow-up of 11·8 years with 1779 participants, nominally significant trends towards a slower decline in cognitive function were observed among those with higher flavanol and flavan-3-ol intakes for global function, verbal and visual memory; higher total flavonoids and flavonoid polymers for visual memory; and higher flavanols for verbal learning.Conclusions:In spite of modest nominal trends, overall, our findings do not support a clear association between higher long-term flavonoid intake and slowing age-related cognitive decline.
Regional planning for meaningful person-centred care in mental health: context is the signal not the noise
Authors: Rock D. , Cross S. P. 
Published: February 2020

Abstract
Person-centred care is at the core of a value-based health system. Its transformative potential is to enable and support key policy, planning and service developments across the system even when these go against the self-interest of individual major players. It offers a potent test for decision makers at all levels. It demands responses that are multi-level, empirically grounded, expert-informed and data-driven that must converge on the singularity of individuals in the places that they live. This requires different approaches that recognise, respect and reconcile two necessary but constitutionally disparate perspectives: the bureaucratic, overtly decontextualised, top-down, policy and planning objectives of central governments and the formally complex, dynamic and contextualised experience of individuals in the system. Conflating the latter with the former can lead unwittingly to a pervasive and reductive form of quasi-Taylorism that nearly always creates waste at the expense of value. This has parallel application in the treatment domain where outcomes are non-randomly clustered and partitioned by socioeconomic status, amplifying unwarranted variation by place that is striking in its magnitude and heterogeneity. In this paper, we propose that a combination of (1) relevant, local and sophisticated data planning, collection and analysis systems, (2) more detailed person-centred service planning and delivery and (3) system accountability through co-design and transparent public reporting of health system performance in a manner that is understandable, relevant, and locally applicable are all essential in ensuring planned and provided care is most appropriate to more than merely the ‘average’ person for whom the current system is built. We argue that only through a greater appreciation of healthcare as a complex adaptive (eco)system, where context is everything, and then utilising planning, analysis and management methodologies that reflect this reality is the way to achieve genuine person-centred care.
Active Fault Scarps in Southern Malawi and Their Implications for the Distribution of Strain in Incipient Continental Rifts
Authors: Wedmore L. N. J. , Biggs J. , Williams J. N. , Fagereng Å. , Dulanya Z. , Mphepo F. , Mdala H. 
Published: February 2020

AbstractThe distribution of deformation during the early stages of continental rifting is an important constraint on our understanding of continental breakup. Incipient rifting in East Africa has been considered to be dominated by slip along rift border faults, with a subsequent transition to focused extension on axial segments in thinned crust and/or with active magmatism. Here, we study high‐resolution satellite data of the Zomba Graben in southern Malawi, an amagmatic rift whose topography is dominated by the west‐dipping Zomba fault. We document evidence for five subparallel fault scarps between 13 and 51 km long spaced ~10–15 km apart. The scarps consist of up to five segments between 4 and 18 km long, separated by minima in scarp height and river knickpoints. The maximum height of each fault scarp ranges from 9.5 ± 4.2 m to 35.3 ± 14.6 m, with the highest scarp measured on the intrabasin Chingale Step fault. We estimate that the scarps were formed by multiple earthquakes of up to Mw7.1 and represent a previously unrecognized seismic hazard. Our calculations show that 55 ± 24% of extensional strain is accommodated across intrabasin faults within the ~50 km wide rift. This demonstrates that a significant proportion of displacement can occur on intrabasin faults during early‐stage rifting, even in thick continental lithosphere with no evidence for magmatic fluids.
An Experimental Study of Longitudinal Incisional Grooves in a Mixed Bedrock–Alluvial Channel
Authors: Inoue Takuya , Nelson Jonathan M. 
Published: February 2020

AbstractNatural bedrock rivers have various bedforms created by erosion. Flow‐parallel incisional grooves formed longitudinally in bedrock are one common example of such bedforms. Although several studies have been conducted regarding these grooves, their formation processes are not well understood. In this study, we conducted a flume experiment to investigate the relationship between the flow structure and longitudinal grooves. The experimental results strongly suggest that longitudinal grooves are formed by moving sediment concentrated in multiple longitudinal pathways by turbulence‐driven secondary flows. The sediment preferentially abrades the bedrock along these flow‐parallel pathways resulting in longitudinal grooves in the bedrock. Measurements of the flow velocity distribution show that the positions of secondary flow cells producing the initial formation of the grooves are altered by the formation of those grooves. Because displaced secondary flows tend to make the sediment collide with the sidewalls of the longitudinal grooves, the grooves grow wider over time and some grooves partially combine with other adjacent grooves. The initial maximum number of longitudinal grooves Nmax strongly depends on the river width‐depth ratio B/D, which defines the number of secondary flow cells, and can be expressed as Nmax = 0.5B/D. However, because some grooves coalesce with other grooves due to the effects of the displacement of secondary flows, the average number of grooves showed a relationship that can be expressed as N = 0.41B/D. Based on this relationship, we inversely estimated the flow discharge of the Abashiri River using the number of longitudinal grooves observed in the river. The result was consistent with the observed annual maximum flow discharge of the river. This suggests that the number of longitudinal grooves can be used as an indicator for estimation of the formative flow discharge in bedrock rivers.
Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury
Authors: Pan Hong , Steixner-Kumar Agnes A. , Seelbach Anna , Deutsch Nadine , Ronnenberg Anja , Tapken Daniel , von Ahsen Nico , Mitjans Marina , Worthmann Hans , Trippe Ralf , Klein-Schmidt Christina , Schopf Nadine , Rentzsch Kristin , Begemann Martin , Wienands Jürgen , Stöcker Winfried , Weissenborn Karin , Hollmann Michael , Nave Klaus-Armin , Lühder Fred , Ehrenreich Hannelore 
Published: February 2020

AbstractCirculating autoantibodies (AB) of different immunoglobulin classes (IgM, IgA, and IgG), directed against the obligatory N-methyl-d-aspartate-receptor subunit NR1 (NMDAR1-AB), belong to the mammalian autoimmune repertoire, and appear with age-dependently high seroprevalence across health and disease. Upon access to the brain, they can exert NMDAR-antagonistic/ketamine-like actions. Still unanswered key questions, addressed here, are conditions of NMDAR1-AB formation/boosting, intraindividual persistence/course in serum over time, and (patho)physiological significance of NMDAR1-AB in modulating neuropsychiatric phenotypes. We demonstrate in a translational fashion from mouse to human that (1) serum NMDAR1-AB fluctuate upon long-term observation, independent of blood–brain barrier (BBB) perturbation; (2) a standardized small brain lesion in juvenile mice leads to increased NMDAR1-AB seroprevalence (IgM + IgG), together with enhanced Ig-class diversity; (3)CTLA4(immune-checkpoint) genotypes, previously found associated with autoimmune disease, predispose to serum NMDAR1-AB in humans; (4) finally, pursuing our prior findings of an early increase in NMDAR1-AB seroprevalence in human migrants, which implicated chronic life stress as inducer, we independently replicate these results with prospectively recruited refugee minors. Most importantly, we here provide the first experimental evidence in mice of chronic life stress promoting serum NMDAR1-AB (IgA). Strikingly, stress-induced depressive-like behavior in mice and depression/anxiety in humans are reduced in NMDAR1-AB carriers with compromised BBB where NMDAR1-AB can readily reach the brain. To conclude, NMDAR1-AB may have a role as endogenous NMDAR antagonists, formed or boosted under various circumstances, ranging from genetic predisposition to, e.g., tumors, infection, brain injury, and stress, altogether increasing over lifetime, and exerting a spectrum of possible effects, also including beneficial functions.
Phase-adjusted estimation of the number of Coronavirus Disease 2019 cases in Wuhan, China
Authors: Wang Huwen , Wang Zezhou , Dong Yinqiao , Chang Ruijie , Xu Chen , Yu Xiaoyue , Zhang Shuxian , Tsamlag Lhakpa , Shang Meili , Huang Jinyan , Wang Ying , Xu Gang , Shen Tian , Zhang Xinxin , Cai Yong 
Published: February 2020

AbstractAn outbreak of clusters of viral pneumonia due to a novel coronavirus (2019-nCoV/SARS-CoV-2) happened in Wuhan, Hubei Province in China in December 2019. Since the outbreak, several groups reported estimated R0 of Coronavirus Disease 2019 (COVID-19) and generated valuable prediction for the early phase of this outbreak. After implementation of strict prevention and control measures in China, new estimation is needed. An infectious disease dynamics SEIR (Susceptible, Exposed, Infectious, and Removed) model was applied to estimate the epidemic trend in Wuhan, China under two assumptions of Rt. In the first assumption, Rt was assumed to maintain over 1. The estimated number of infections would continue to increase throughout February without any indication of dropping with Rt = 1.9, 2.6, or 3.1. The number of infections would reach 11,044, 70,258, and 227,989, respectively, by 29 February 2020. In the second assumption, Rt was assumed to gradually decrease at different phases from high level of transmission (Rt = 3.1, 2.6, and 1.9) to below 1 (Rt = 0.9 or 0.5) owing to increasingly implemented public health intervention. Several phases were divided by the dates when various levels of prevention and control measures were taken in effect in Wuhan. The estimated number of infections would reach the peak in late February, which is 58,077–84,520 or 55,869–81,393. Whether or not the peak of the number of infections would occur in February 2020 may be an important index for evaluating the sufficiency of the current measures taken in China. Regardless of the occurrence of the peak, the currently strict measures in Wuhan should be continuously implemented and necessary strict public health measures should be applied in other locations in China with high number of COVID-19 cases, in order to reduce Rt to an ideal level and control the infection.