bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of systemic conditions, tooth loss, body image, and quality of life of women with obesity and women who underwent gastric bypass surgery
Authors: Foratori‐Junior Gerson Aparecido , Máscoli Leonardo Silva , Jesuino Bruno Gualtieri , Missio Alana Luiza Trenhago , Sales‐Peres Silvia Helena de Carvalho 
Published: February 2020

AbstractAimTo evaluate the systemic conditions, tooth loss, oral health, body image perceptions, and quality of life of women with obesity and women who underwent bypass surgery.Methods and resultsSixty women were classified into the gastric bypass (G1, n = 30) and obesity (G2, n = 30) groups, and their systemic condition, oral health perception, oral hygiene, tooth loss, body image perception (Stunkard scale), and quality of life (WHOQOL‐bref) were evaluated. The t‐test, Mann‐Whitney, chi‐square, and multiple linear regression were used for statistical analysis (P < .05). G2 presented higher prevalence of hypertension (P = .020) and G1 higher prevalence of anemia (P = .040). G2 demonstrated less favorable perceptions of oral health, primarily associated with chewing (P = .0007) and speech (P = .005), and a lower frequency of dental floss usage (P = .047); however, there were no intergroup differences regarding the prevalence of missing teeth (P = .180). G1 demonstrated greater satisfaction with regard to their body image (P < .0001), contrary to those in G2, who negatively perceived the same (P = .001), particularly considering the physical, psychological, and environmental parameters (P < .05).ConclusionHigh body mass index (BMI) indicated a higher prevalence of hypertension and a negative impact on oral health perception and quality of life. However, bariatric surgery was associated with a positive body image perception and quality‐of‐life parameters.
Hidden Trilogies of Universal Quantifiers: A syntactically based analysis of arabickulland its kins
Authors: Fassi Fehri Abdelkader 
Published: February 2020

AbstractDistinct senses of universal quantification are expressed not only byvocabularyinventory variation, but also throughfeaturesandcategorieswhich build the various quantifier types. It can be shown that the most productive Arabic universalkull(and arguably its kins in Semitic and other languages) conveysthreeuniversal quantifier senses, roughly equivalent to Englishall,every, andeach(and not only justtwo, as commonly assumed). Similar trilogies are observed in Greek, French, or Hebrew (with two Q words, or just one). Thanks to their feature and category specifications, universal subtypes are more appropriately characterized in terms of Merge and Move syntactic operations, as in Chomsky (1995), Beghelli and Stowell (1997), and they conform to internal composition of variational quantifier meaning (as in e.g. Szabolcsi 2010, Mathewson 2013), and appealing results about distributivity (Tunstall 1998 & Champollion 2017, among others).
Reliability of labeling red cell units with minor antigen historical results and process considerations
Authors: DePalma Helene , Godbey Elizabeth A. , Opalka Andrew , Parsi Mahdokht , Vege Sunitha , Lomas‐Francis Christine , Westhoff Connie M. 
Published: February 2020

ABSTRACTBACKGROUNDSeveral approaches are used by blood centers when providing minor (non‐ABO/D) antigen‐negative RBCs to hospitals. Details vary but include providing results on the unit labeling intended for clinical use without retyping or providing results on packing documents or via computer query requiring confirmation. Recent regulatory changes allow labeling with historical minor antigen results, defined as previously performed by the donor center on two different donations with results linked to the donor and confirmed concordant. Here we investigate causes of discrepancies and identify critical process steps.STUDY DESIGN AND METHODSNine years (2009‐2017) of data were reviewed for number, antigen system, and root cause of discrepancies flagged by the computer when retyping donors prior to labeling (internal discrepancies) or reported by the hospital when retested (external discrepancies). Licensed automated (CcEeK) and tube methods were used.RESULTSAmong 300,000 samples phenotyped for CcEe, K, Fya/b, Jka/b, Ss (>3 million antigens), ∼1,389,960 were repeated on 2nd donation with 397 (1/3501) discordant; 205 Fy, 118 Rh, and 74 others. Of ∼682,691 antigen‐negative phenotypes provided on unit labeling, ∼37.5% (256,118) were retyped by hospitals with 29 discrepancies (1/8832), primarily Rh variants.CONCLUSIONWhen repeating minor antigen types by serology, discrepancies are primarily associated with weak Fyb, among Caucasian donors, and weak/partial Rh antigens in donors of African ancestry. DNA‐based testing avoids these. To label with historical results, accuracy is increased by automated testing with direct computer interface. Testing on two donations with results confirmed to be concordant is not inferior to testing on the current donation.
Risk factors for equine recurrent uveitis in a population of Appaloosa horses in western Canada
Authors: Sandmeyer Lynne S. , Kingsley Nicole B. , Walder Cheryl , Archer Sheila , Leis Marina L. , Bellone Rebecca R. , Bauer Bianca S. 
Published: February 2020

AbstractObjectiveTo characterize clinical manifestations, measure frequency, and evaluate risk factors for equine recurrent uveitis (ERU) in Appaloosa horses in western Canada.Animals145 Appaloosa horses.ProceduresOphthalmic examinations were completed and eyes were classified as having no or mild clinical signs, or moderate, or severe damage from ERU. Clinical signs, age, sex, base coat color, and pattern were recorded. Whole blood and/or mane hair follicles were collected for DNA extraction, and all horses were tested for the leopard complex (LP) spotting pattern allele. Pedigree analysis was completed on affected and unaffected horses, and coefficients of coancestry (CC) and inbreeding (COI) were determined.ResultsEquine recurrent uveitis was confirmed in 20 (14%) horses. The mean age of affected horses was 12.3 years (±5.3; range 3‐25). Age was a significant risk factor for ERU diagnosis (ORyear = 1.15) and classification (ORyear = 1.19). The fewspot coat pattern was significantly associated with increased risk for ERU compared to horses that were minimally patterned or true solids. TheLP/LPgenotype was at a significantly greater risk for ERU compared tolp/lp(OR = 19.4) andLP/lp(OR = 6.37). Classification of ERU was greater in theLP/LPgenotype compared toLP/lp. Affected horses had an average CC of 0.066, and there was a significant difference in the distribution of CC for affected horses versus the control group (P = .021). One affected horse was the sire or grandsire of nine other affected.ConclusionsAge, coat pattern, and genetics are major risk factors for the diagnosis and classification of ERU in the Appaloosa.
Comparison of femoral stem subsidence between three types of press‐fit cementless total hip replacement in dogs
Authors: Mitchell Megan M. , Hudson Caleb C. , Beale Brian S. 
Published: February 2020

AbstractObjectiveTo compare femoral stem subsidence and determine contributing factors in dogs undergoing total hip replacement (THR) with the traditional BFX, collared BFX, and BFX lateral bolt stems.Study designRetrospective radiographic study.Sample populationNinety‐three dogs with 101 THR including dogs undergoing THR with a BFX lateral bolt femoral stem (n = 40), BFX collared stem (n = 21), and traditional BFX stem (n = 40).MethodsRadiographs of traditional BFX (n = 40), collared BFX (n = 21), and BFX lateral bolt (n = 40) THR performed from 2015 to 2018 were reviewed. Subsidence, canal flare index (CFI), stem canal fill (CF), stem orientation, and complications confirmed on radiographs were recorded at postoperative and recheck radiographs. Analysis of variance tests were used to compare subsidence, CFI, stem orientation, and CF. A χ2 analysis was performed to compare complication rates between groups.ResultsSubsidence was lower after placement of BFX lateral bolt stems (median, 0.24 mm; interquartile range [IQR; 1.49) compared with collared (1.27 mm [2.29]) and BFX (1.35 mm [2.26]) stems. No difference in subsidence was detected between collared and BFX implants. Coronal CF was greater after placement of BFX (mean ± SD, 0.72 ± 0.06) compared with lateral bolt (0.69 ± 0.05) or collared (0.66 ± 0.07) stems. Sagittal CF differed between all groups (BFX 0.7 ± 0.05, lateral bolt 0.67 ± 0.06, and collared 0.61 ± 0.06). No differences were identified in CFI or stem orientation in the coronal and sagittal planes or in complication rates between implants.ConclusionThe BFX lateral bolt femoral stem was associated with less postoperative subsidence compared with the BFX collared and traditional BFX stems. No consistent changes in CF, CFI, or stem orientation or complication rates were identified in association with increased subsidence in this study.Clinical significanceImplantation of a lateral bolt femoral stem should be considered during THR to prevent subsidence.
Low‐dose lithium feeding increases the SERCA2a‐to‐phospholamban ratio, improving SERCA function in murine left ventricles
Authors: Hamstra Sophie I. , Kurgan Nigel , Baranowski Ryan W. , Qiu Liqun , Watson Colton J. F. , Messner Holt N. , MacPherson Rebecca E. K. , MacNeil Adam J. , Roy Brian D. , Fajardo Val A. 
Published: February 2020

New Findings

What is the central question of this study?
Inhibition of glycogen synthase kinase‐3 (GSK3) has been shown to improve cardiac SERCA2a function. Lithium can inhibit GSK3, but therapeutic doses used in treating bipolar disorder can have toxic effects. It has not been determined whether subtherapeutic doses of lithium can improve cardiac SERCA function.

What is the main finding and its importance?
Using left ventricles from wild‐type mice, we found that subtherapeutic lithium feeding for 6 weeks decreased GSK3 activity and increased cardiac SERCA function compared with control‐fed mice. These findings warrant the investigation of low‐dose lithium feeding in preclinical models of cardiomyopathy and heart failure to determine the therapeutic benefit of GSK3 inhibition.
AbstractThe sarco(endo)plasmic reticulum Ca2+‐ATPase (SERCA) pump is responsible for regulating calcium (Ca2+) within myocytes, with SERCA2a being the dominant isoform in cardiomyocytes. Its inhibitor, phospholamban (PLN), acts by decreasing the affinity of SERCA for Ca2+. Changes in the SERCA2a:PLN ratio can cause Ca2+ dysregulation often seen in patients with dilated cardiomyopathy and heart failure. The enzyme glycogen synthase kinase‐3 (GSK3) is known to downregulate SERCA function by decreasing the SERCA2a:PLN ratio. In this study, we sought to determine whether feeding mice low‐dose lithium, a natural GSK3 inhibitor, would improve left ventricular SERCA function by altering the SERCA2a:PLN ratio. To this end, male wild‐type C57BL/6J mice were fed low‐dose lithium via drinking water (10 mg kg−1 day−1 LiCl for 6 weeks) and left ventricles were harvested. GSK3 activity was significantly reduced in LiCl‐fed versus control‐fed mice. The apparent affinity of SERCA for Ca2+ was also increased (pCa50; control, 6.09 ± 0.03 versus LiCl, 6.26 ± 0.04, P < 0.0001) along with a 2.0‐fold increase in SERCA2a:PLN ratio in LiCl‐fed versus control‐fed mice. These findings suggest that low‐dose lithium supplementation can improve SERCA function by increasing the SERCA2a:PLN ratio. Future studies in murine preclinical models will determine whether GSK3 inhibition via low‐dose lithium could be a potential therapeutic strategy for dilated cardiomyopathy and heart failure.
Development and thyroid hormone dependence of skeletal muscle mitochondrial function towards birth
Authors: Davies K. L. , Camm E. J. , Atkinson E. V. , Lopez T. , Forhead A. J. , Murray A. J. , Fowden A. L. 
Published: February 2020

Key points
Skeletal muscle energy requirements increase at birth but little is known regarding the development of mitochondria that provide most of the cellular energy as ATP.
Thyroid hormones are known regulators of adult metabolism and are important in driving several aspects of fetal development, including muscle fibre differentiation.
Mitochondrial density and the abundance of mitochondrial membrane proteins in skeletal muscle increased during late gestation. However, mitochondrial functional capacity, measured as oxygen consumption rate, increased primarily after birth.
Fetal hypothyroidism resulted in significant reductions in mitochondrial function and density in skeletal muscle before birth.
Mitochondrial function matures towards birth and is dependent on the presence of thyroid hormones, with potential implications for the health of pre‐term and hypothyroid infants.
AbstractBirth is a significant metabolic challenge with exposure to a pro‐oxidant environment and the increased energy demands for neonatal survival. This study investigated the development of mitochondrial density and activity in ovine biceps femoris skeletal muscle during the perinatal period and examined the role of thyroid hormones in these processes. Muscle capacity for oxidative phosphorylation increased primarily after birth but was accompanied by prepartum increases in mitochondrial density and the abundance of electron transfer system (ETS) complexes I–IV and ATP‐synthase as well as by neonatal upregulation of uncoupling proteins. This temporal disparity between prepartum maturation and neonatal upregulation of mitochondrial oxidative capacity may protect against oxidative stress associated with birth while ensuring energy availability to the neonate. Fetal thyroid hormone deficiency reduced oxidative phosphorylation and prevented the prepartum upregulation of mitochondrial density and ETS proteins in fetal skeletal muscle. Overall, the data show that mitochondrial function matures over the perinatal period and is dependent on thyroid hormones, with potential consequences for neonatal viability and adult metabolic health.
Integrity Assessment of Internally Corroded Pipelines Rehabilitated With a Kevlar-Reinforced Flexible Liner
Authors: Fahed M. , Barsoum I. , Alfantazi A. , Islam M. D. 
Published: February 2020

Abstract
Contemporary approach of corrosion prevention is to use internal lining system to isolate the corrosive medium from the host pipe's inner surface. The liners serve to offer a longer lifecycle of pipelines, as well as a corrosion barrier against aggressive chemical agents. A recent lining technology based on a Kevlar-reinforced flexible polymer composite liner called the InField Liner (IFL) has been successfully installed in several pipelines. It has been theorized that the added inherent strength of the liner due to the Kevlar-reinforcement can give rise to an increase in burst pressure level of the corroded pipeline. The mechanical response of the IFL liner is established accurately and used to define the constitutive behavior of the IFL material in a nonlinear finite element model of liner installed in a host pipe with internal corrosion defect. The results reveal that an increase in burst pressure is achieved with the IFL liner, which is attributed to the interaction between the IFL and the internal corrosion defect. The increase in burst pressure is especially noted for rather deep and short length defects. The primary reason to the increase is the stretch of the Kevlar fabric into the defect cavity inducing a load transfer between the liner and pipe at the defect zone. A closed-form solution is developed, which can be used to assess the increase in burst of pipelines containing internal corrosion defects when rehabilitated with an IFL liner. The results of the study demonstrate that the IFL internal lining technology can be used as a corrosion barrier in steel pipelines for rehabilitation of old pipelines, as well as providing an increase in burst pressure level when the liner is installed due to its complex interaction with the internal corrosion defect.
Assessment on Strain-Based and Stress-Based Design Strategies for Components at Elevated Temperatures: A Comparative Study
Authors: Niu Tian-Ye , Gong Cheng , Gong Jian-Guo , Xuan Fu-Zhen , Chen Haofeng 
Published: February 2020

Abstract
Geometrical discontinuities (such as holes and grooves) widely exist in many components, which operate at elevated temperatures. Creep assessment of the geometrical discontinuities is essential for the safe operation of the system. In general, creep evaluations are conducted from the stress-based and strain-based strategies, but comparative studies on the extent of conservatism of these two design strategies are rarely included. In this work, creep test data of the notched components made of 9–12% Cr steel conducted by authors and that of 9Cr–1Mo steel collected from published works are employed for comparative evaluations. Results indicate that strain-based and stress-based strategies are both relatively conservative for notches in metal materials, and the conservatism of the assessment strategies increases with the notch acuity ratio of the component. The differences of the conservatism for strain-based and stress-based strategies are dependent on the notch acuity ratio and the ductility of the materials. For a blunt notch, the strain-based strategy is more conservative than the stress-based strategy for materials mentioned, while the dominant assessment strategy is dependent on stress redistribution performances of components with a sharp notch.
Evaluation of Stress Rupture Factors for Grade 91 Weldments
Authors: Kimura Kazuhiro , Yaguchi Masatsugu 
Published: February 2020

Abstract
Stress rupture factors and weld strength reduction factors for Grade 91 steel weldments in the codes and literatures have been reviewed. Stress rupture factors for weld metals proposed for code case N-47 in the mid 1980's was defined as a ratio of average rupture strength of the deposited filler metal to the average rupture strength of the base metal. Remarkable drop in creep rupture strength of weldments is significant issue of Grade 91, especially in the low-stress and long-term regime. A premature failure of Grade 91 steel weldments in the long-term, however, is caused by type IV failure which takes place in the fine grain heat affected zone (FG-HAZ), rather than fracture in the deposited weld metal. The stress rupture factor of the Grade 91 steel, therefore, was based on the creep rupture strength of cross weld test specimens. Creep rupture data of Grade 91 steel weldments reported in the publication of ASME STP-PT-077 were integrated with the creep rupture data collected in Japan and used for this study. Time- and temperature-dependent stress rupture factors for Grade 91 steel have been evaluated based on the consolidated database as a ratio of average creep rupture strength of cross weld test specimen to the average creep rupture strength of base metal.
Validation of the Moody and Henry–Fauske Critical Flow Models in apros Against Marviken Critical Flow Experiments
Authors: Tesinsky Milan 
Published: February 2020

Abstract
The Moody and Henry–Fauske critical flow models implemented in Advanced Process Simulation Software (apros) have been validated against Marviken critical flow experiments and compared with other available simulations of the same experiments. Both models in combination with discharge coefficient 0.75 (suggested for best estimate calculations) produce results close to the experimental data for two-phase flows, while one-phase flow of subcooled water is underpredicted. Using discharge coefficient 1.0 for subcooled water leads to a good match with the experimental results, while two-phase flows become overpredicted.
Tubular Locomotion and Positioning Using Tip Eversion for Endoscopy
Authors: Saxena Ankit , Pauli Eric M. , Haluck Randy S. , Fell Barry , Moore Jason 
Published: February 2020

Abstract
Colonoscopy is a minimally invasive procedure to examine the large intestine using a flexible endoscope. Currently, colonoscopic procedures require physically pushing the endoscope through the large intestine which potentially imparts damaging forces on the intestinal wall, requires a high level of expertise to perform safely, and can require extensive procedure time. This paper presents the use of inverted tubular element locomotion (ITEL) for improved endoscope translation and positioning that works via tip eversion of inverted plastic tubes. Experiments were performed to examine the fluid pressure required for locomotion through a large intestinal model and in both straight and curved paths and determine the optimal tube dimensions for insertion via ITEL. Experiments were then performed to compare intestinal forces during manual and ITEL-based insertion. The experiments established a relationship between the tip eversion pressure and the tube thickness and diameter. In addition, it was found that pressure required for locomotion was only minimally impeded by being enclosed in the intestinal manikin but significantly impacted by the curvature of the turn. Measured insertion forces for ITEL were found to be 10.1% less compared to traditional insertion. These results will aid in the future design and development of ITEL for endoscopic positioning.
Modal Control for Active Vibration Damping of Cable-Driven Parallel Robots
Authors: Cuvillon Loïc , Weber Xavier , Gangloff Jacques 
Published: February 2020

Abstract
Cable-driven parallel robots are well suited for applications that require a very large workspace. Thanks to their lightweight moving parts, they can achieve high dynamics while remaining pretty safe for nearby human workers. Furthermore, their size depends only on the length of the cables; thus, their scale is almost totally decoupled from their cost. However, due to the cables, the stiffness is very low with respect to rigid link robots, inducing slowly damped oscillations of the end effector. Previous works have shown that those vibrations can be effectively damped by the winch actuators thanks to active vibration damping techniques. In this paper, a gain scheduling approach is proposed based on a linearized model of the robot dynamics. This model is projected in the modal space yielding six decoupled transfer functions for six degrees-of-freedom (DoFs) of a cable-driven parallel robot using thin cables. The stability of the proposed control law is analyzed for a static and a moving end effector. The proposed control algorithm is validated experimentally on an eight-cable suspended robot prototype.
Efficient Spot Welding Sequence Optimization in a Geometry Assurance Digital Twin
Authors: Tabar Roham Sadeghi , Wärmefjord Kristina , Söderberg Rikard , Lindkvist Lars 
Published: February 2020

Abstract
A digital twin for geometry assurance contains a set of analyses that are performed to steer the real production for securing the geometry of the final assembly. In sheet metal assemblies, spot welding is performed to join the parts together. The sequence of the welding has a considerable influence on the geometrical outcome of the final assembly. In industry, the sequence of welding to secure the geometry is mainly derived by tacit manufacturing knowledge. Including such knowledge to mimic the production process requires extensive knowledge management, and the result might be just a good enough solution. Theoretically, spot welding sequence optimization for the optimal geometrical quality is among NP-hard combinatorial problems. In a geometry assurance digital twin, where assembly parameters are selected for the individual assemblies, time constraints define the quality of the optimal sequence. In this paper, an efficient method for spot welding sequence optimization with regards to the geometrical quality is introduced. The results indicate that the proposed method reduces 60–80% of the time for the sequencing of the spot welding process to achieve the optimal geometrical quality.