bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bisphenol-A and polycystic ovary syndrome: a review of the literature
Authors: Kechagias Konstantinos S. , Semertzidou Anita , Athanasiou Antonios , Paraskevaidi Maria , Kyrgiou Maria 
Published: July 2020

Abstract
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age with reproductive, metabolic and endocrine implications. While the exact pathophysiological mechanisms of the syndrome are unknown, its heterogeneity suggests a multifactorial causal background. In the last two decades, numerous environmental chemicals, including Bisphenol-A (BPA) that is used in the synthesis of polycarbonate plastics, have been proposed as potential contributors to the aetiology of PCOS. This review provides a holistic overview of the available data regarding the possible relation of PCOS with BPA exposure. We have included a total number of 24 studies. Eleven human case-control and 13 animal studies provided data regarding this potential relation. Accumulating evidence suggests that a correlation between high levels of BPA and the presence of PCOS may exist. Contradicting results from human and animal studies, however, render it difficult to conclude on the exact role of BPA in the pathogenesis of PCOS. BPA may constitute a consequence of the syndrome rather than a cause, but further research is still needed to clarify this. Continued efforts to study the early origins of PCOS, using prospective-designed studies, are required to identify the exact effect of BPA on women with PCOS.
Le plan de l’expression des images: Quelques réflexions sur support et apport
Authors: Dondero Maria Giulia 
Published: July 2020

AbstractIn this article we plan to revisit the notion of substance of the plane of expression, as found in semiotic studies of the image, and how this notion relates to the concepts of purport and form. The article is divided into three parts: The first section gives a brief history of the various ways substance has been addressed in (or excluded from) image analyses based on Greimassian semiotics and Groupe μ rhetoric. Drawing upon Jacques Fontanille’s semiotics of practices and Jean-François Bordron’s theory of iconicity, the second section concerns proposals that attempt to address the “moment” of giving substance in autographic works of art – and also in writing –, through notions of support, application, and the gestural act of inscription. The third section tests these methodological tools on chemical photography and on digital image-making in order to propose a new, specifically semiotic approach to studying the media characteristics of images.
„Das war mir dann zu weit weg von der Quelle“
Authors: Küper Judith , Thiel Corrie 
Published: July 2020

ZusammenfassungReflexion gilt im Lehrer*innenbildungsdiskurs als Qualitätsgarant. Mit ihr soll das Problem routinisierten Denkens und Handelns bearbeitet werden, indem gewohnte Denk- und Handlungsmuster unter Bezug auf wissenschaftliches Wissen hinterfragt werden. Empirische Untersuchungen zeigen aber, dass Reflexion dieser Art in schulpraktischen Reflexionsformaten kaum stattfindet. Diese Beobachtung wird in dem Beitrag zum Anlass genommen, um ausgehend von einem weiten Verständnis von Reflexion als Rückbeuge auf die eigene Praxis zu untersuchen, wie sich Reflexion in der praktischen Lehrer*innenbildung vollzieht, um von hier aus den Reflexionsbegriff des Lehrer*innenbildungsdiskurses weiterzuentwickeln. Hierfür wird eine Szene aus einem Unterrichtsnachgespräch, das im Rahmen eines Unterrichtsbesuches im Kontext des Referendariats stattfand, gesprächsanalytisch ausgewertet. Anschließend wird vorgeschlagen, mittranszendierenderundsituierenderReflexion zwischen zwei Reflexionsformen zu unterscheiden, die jeweils eigene Leistungen in der Ausbildung von Lehrkräften erbringen. Der Beitrag schließt mit der Darstellung von Implikationen der vorgestellten Befunde für die weitere Diskussion von Reflexion in der Lehrer*innenbildung.
Doubly constrained totally positive line insertion
Authors: Johnson Charles R. , Allen David W. 
Published: July 2020

AbstractIt is shown that in any TP matrix, a line (row or column) with two speci˝ed entries in any positions (and the others appropriately chosen) may be inserted in any position, as long as the two entries are consistent with total positivity. This generalizes an unconstrained result previously proven, and the two may not generally be increased to three or more. Applications are given, and this fact should be useful in other completion problems, as the unconstrained result has been.
Basal contralateral aldosterone suppression is rare in lateralized primary aldosteronism
Authors: Desrochers Marie-Josée , St-Jean Matthieu , El Ghorayeb Nada , Bourdeau Isabelle , So Benny , Therasse Éric , Kline Gregory , Lacroix André 
Published: July 2020

Context:
Unilateral aldosteronomas should suppress renin and contralateral aldosterone secretion. Complete aldosterone suppression in contralateral adrenal vein sample (AVS) could predict surgical outcomes.

Objectives:
To retrospectively evaluate the prevalence of basal contralateral suppression using Aldosterone (A)contralateral(CL)/Aperipheral(P) as compared to (A/Cortisol(C)CL)/(A/C)P ratio in primary aldosteronism (PA) patients studied in two Canadian centers. To determine the best cut-off to predict clinical and biochemical surgical cure. To compare the accuracy of ACL/AP to the basal and post-ACTH lateralization index (LI) in predicting surgical cure.

Methods:
In total, 330 patients with PA and successful AVS were included; 124 lateralizing patients underwent surgery. Clinical and biochemical cure at 3 and 12 months were evaluated using the PASO criteria.

Results:
Using ACL/AP and (A/C)CL/(A/C)P at the cut-off of 1, the prevalence of contralateral suppression was 6 and 45%, respectively. Using ROC curves, the ACL/AP ratio is associated with clinical cure at 3 and 12 months and biochemical cure at 12 months. (A/C)CL/(A/C)P is associated with biochemical cure only. The cut-offs for ACL/AP offering the best sensitivity (Se) and specificity (Sp) for clinical and biochemical cures at 12 months are 2.15 (Se: 63% and Sp: 71%) and 6.15 (Se: 84% and Sp: 77%), respectively. Basal LI and post-ACTH LI are associated with clinical cure but only the post-ACTH LI is associated with biochemical cure.

Conclusions:
In lateralized PA, basal contralateral suppression defined by ACL/AP is rare and incomplete compared to the (A/C)CL/(A/C)P ratio and is associated with clinical and biochemical postoperative outcome, but with modest accuracy.
ÇOCUKLARIN BOYU VE SÜT DİŞLERİNİN KURON BOYUTLARI ARASINDAKİ İLİŞKİ
Authors: ÖZCAN Hazal , YILMAZ Buse , UZ Sinem , İLİSULU Sabiha Ceren , AYDIN Ceren , KORUYUCU Mine , SEYMEN Figen 
Published: July 2020

Amaç:Diş gelişimi, çocuklarda
büyüme ve gelişmenin önemli bir göstergesidir. Büyüme sürecinde boy ve kilo
artışı ile diş boyutlarının artışı birbirlerine paralel seyreden
parametrelerdir. Bu çalışmanın amacı; süt dişlerinin kuron boyu ve meziodistal
(MD) genişlikleri ile çocuğun boyu, kilosu ve vücut kitle indeksi (VKİ)
arasındaki ilişkinin belirlenmesidir. Gereç ve Yöntemler:Çalışmaya;
İstanbul Üniversitesi Diş Hekimliği Fakültesi Pedodonti Anabilim Dalı kliniğine
başvurmuş olan 3-6 yaş grubu 68 çocuk (34 kız, 34 erkek) dahil edilmiştir.
Çocukların alt-üst çenesinden ölçü alınarak elde edilen alçı model üzerinden
dijital bir kumpas yardımıyla dişlerin klinik kuron boyu ve meziodistal
genişlik uzunlukları ile çocukların kilo, boy ve yaş değerleri kaydedilmiştir.
Kaydedilen bu değerler arasındaki ilişki istatiksel olarak değerlendirilmiştir.Bulgular:Çalışmaya katılan 68 çocuğun
25’i (%36,8) 3-4 yaş grubunda iken 22’si (%32,4) 5 yaş grubuna, 21’i ise
(%30,9) 6 yaş grubuna dahildir. Tüm yaş gruplarında 5. ve 7. bölgedeki dişlerin
kuron boyu ortalamaları arasında ve meziodistal genişliği arasında anlamlı bir
fark bulunmuştur (p=0,001). Gruplar arası karşılaştırmada erkeklerde #53
numaralı dişin kuron boyu için istatistiksel olarak anlamlılık saptanmıştır
(p=0,019). Değerlendirmeye alınan tüm dişlerin kuron boyu ve MD genişliği ile
VKİ değişkeni ile karşılaştırılmasında anlamlı bir ilişki bulunamamıştır
(p&gt;0,05).Sonuçlar:Bu çalışmada bireyin boyu
ile dişin meziodistal genişliğine göre bireyin boyu ile kuron boyu arasında daha
kuvvetli korelasyon olduğu belirlenmiştir. Bunun sonucunda süt dişlerinin kuron
boyu ve meziodistal genişliğinin, çocukların muhtemel boylarını tahmin etmede
kullanılması ve vücut ölçüleri arasında ilişki kurulmasının değerlendirilebileceği
düşünülmektedir.Anahtar Kelimeler:kuron boyu, meziodistal
genişlik, vücut kitle indeksi
Farklı asitleme işlemlerinin lityum disilikat seramik sistemlerin yüzey pürüzlülüğü ve bağlanma dayanımı üzerine etkileri
Authors: SAYIN ÖZEL Gülsüm , KARA Özlem 
Published: July 2020

Amaç: Bu
çalışmanın amacı hidroflorik (Hf) asit ve ısıyla uygulanan deneysel asit ile
pürüzlendirilmiş lityum disilikat seramiklerin rezin siman ile mikro gerilim bağlanma
dayanımlarını değerlendirmektir.Gereç ve Yöntemler:Bu
çalışmada 24 adet çürüksüz insan üçüncü molar diş kullanıldı. Dişler akrilik
rezin bloklara mine-sement sınırının 2 mm aşağısında olacak şekilde gömüldü.
Dişler üzerinde paraskop yardımıyla sınıf I inley kaviteler açıldı. Lityum
disilikat seramik restorasyonlar üretici firma talimatına göre üretildi.
Örnekler 2 gruba ayrıldı. 1) % 9’ luk Hf asit 20 sn), 2) ısıyla uygulanan
deneysel asit 30 dk. Simantasyon işlemlerinden sonra örnekler termal siklusa
(5000 siklus) tabi tutuldu. Sonrasında örneklere 1 mm/dk hızla mikro gerilim bağlanma
testi uygulandı. Elde edilen değerlere bağımsız Örneklem T testi yapıldı (p=0.05).
Yüzey pürüzlülüğü ve mikro gerilim bağlanma değerleri arasındaki ilişkiyi
analiz etmek amacıyla pearson korelasyon katsayısıyla korelasyon testi yapıldı (p=0.01).Bulgular:Hf asit lityum disilikat seramik yüzeylerinde deneysel asit ve ısıyla
karşılaştırıldığında daha fazla pürüzlülüğe ve mikro gerilim bağlanma
değerlerine neden olmuştur. Pearson korrelasyon sayısı, pürüzlülük ile mikro
gerilim bağlanma değerleri arasında yüksek bir değerle pozitif yönde bir
korelasyon olduğunu göstermektedir. Sonuçlar:Hf
asitin toksik etkileri nedeniyle lityum disilikat içerikli cam seramikleri pürüzlendirmede
Hf asitten daha iyi alternatif metodların arayışı devam etmektedir. Anahtar Kelimeler:Deneysel
sıcak asit, Hf asit, Mikro gerilim
bağlanma dayanımı
PERAN PEKERJA SOSIAL DALAM PENDAMPINGAN PSIKOSOSIAL ANAK KORBAN KEKERASAN SEKSUAL DI LEMBAGA KONSULTASI KESEJAHTERAAN KELUARGA (LK3) “MELATI” KABUPATEN KARAWANG
Authors: Kartika Al Ashzim Kartika Al Ashzim 
Published: July 2020

Abstract Children are the forerunner of the birth of the next generation that will determine the fate of the nation. Today many children do not get what they are entitled to. That way, the frequent occurrence of violence against children that occurs both in schools, homes, and in public places is more attention to protect children from acts of violence, both physical, psychological and sexual violence. This is the background to understanding the role of social workers in mentoring children victims of sexual violence in LK3 "Melati". This study uses qualitative methods that are descriptive. The results of this study prove that LK3 social workers "Melati" provide assistance by consulting client cases and then referring to relevant institutions. So that the stages of mentoring are carried out using case management stages. The method applied by LK3 social worker "Melati" is casework and case management methods. Of the seven roles of social workers according to Zastrow, social workers at LK3 "Melati" use the role of a case manager in psychosocial assistance to children victims of sexual violence. AbstrakAnak merupakan cikal bakal lahirnya generasi penerus yang akan menentukan nasib bangsa. Saat ini banyak anak yang tidak mendapatkan apa yang menjadi haknya. Dengan begitu, sering terjadinya kekerasan terhadap anak yang terjadi baik di lingkungan sekolah, rumah, maupun di tempat umum menjadi perhatian lebih untuk dapat melindungi anak dari tindak kekerasan, baik kekerasan fisik, psikis maupun seksual. Hal tersebut menjadi latar belakang untuk memahami bagaimana peran pekerja sosial dalam pendampingan anak korban kekerasan seksual di LK3 “melati”. Penelitian ini menggunakan metode kualitatif yang bersifat deskriptif. Hasil penelitian ini membuktikan bahwa pekerja sosial LK3 “melati” melakukan pendampingan dengan cara konsultasi kasus klien dan kemudian merujuk ke lembaga-lembaga yang terkait. Sehingga tahapan pendampingan yang dilakukan yaitu memakai tahapan manajemen kasus. Adapun metode yang diterapkan oleh pekerja sosial LK3 “Melati” adalah metode casework dan manajemen kasus. Dari ketujuh peran pekerja sosial menurut Zastrow, pekerja sosial di LK3 “Melati” lebih menggunakan peran sebagai case manager dalam melakukan pendampingan psikososial terhadap anak korban kekerasan seksual.
DAMPAK PROGRAM ELDERLY DAY CARE SERVICE TERHADAP KESEJAHTERAAN LANSIA DI PANTI SOSIAL TRESNA WERDHA BUDI DHARMA BEKASI
Authors: Yulianti Yulianti 
Published: July 2020

Abstract. Old age is a phase of a human being in the final life stage before the stage of death. At this stage the elderly require various needs and difficulties they experience, such as physical, psychological, social and spiritual challenges. Therefore, the Bekasi Tresna Budi Dharma Social Home has a program to improve the welfare of the elderly. The institution develops a program for the visiting elderly but receiving the same social services. The program is called Elderly Day Care Service. This research aims at the exploration of the program implementation process and the impact of the Elderly Day Care Service program affecting the welfare of the elderly. This research uses a descriptive qualitative approach. The research data collection technique is by means of interviews, observations, and documentation studies. The results show that the Elderly Day Care Service program at Bekasi Tresna Werdha Budi Dharma Social Home reseults a very positive effect on the elderly participating in the program. In addition, physical, psychological, social and spiritual problems are gradually resolved and make a prosperous elder; active, independent and productive. Abstrak. Lanjut usia merupakan fase seorang manusia berada pada tahap kehidupan akhir sebelum tahap kematian. Pada tahap ini lansia memiliki banyak kebutuhan dan permasalahan yang dialaminya, seperti kendala fisik, psikologis, sosial dan spiritual. Maka dari itu Panti Sosial Tresna Budi Dharma Bekasi memiliki program untuk meningkatkan kesejahteraan lansia. Dan Panti Sosial Tresna Werdha Budi Dharma Bekasi mengembangkan sebuah program bagi lansia yang tidak tinggal di panti namun mendapatkan pelayanan sosial yang sama. Program tersebut bernama Pelayanan Harian Lanjut Usia atau Elderly Day Care Service. Penilitian ini bertujuan untuk mengetahui proses pelaksanaan program dan dampak program Elderly Day Care Service yang dilakukan oleh Panti Sosial Tresna Werdha Budi Dharma Bekasi berpengaruh pada kesejahteraan lansia. Pendekatan dalam penelitian ini menggunakan kualitatif jenis deskriptif. Teknik pengumpulan data penelitian merupakan kumpulan data dari wawancara, observasi, dan studi dokumentasi. Hasil penelitian menunjukan bahwa program Elderly Day Care Service di Panti Sosial Tresna Werdha Budi Dharma Bekasi memiliki pengaruh yang sangat positif bagi para lansia yang mengikuti program tersebut. Selain itu, permasalahan baik fisik, psikis, sosial dan spiritual sedikit demi sedikit teratasi dan menjadikan lansia yang sejahtera yaitu aktif, mandiri dan produktif.
KUALITAS KELEKATAN ANAK DENGAN PENGASUH DI LEMBAGA KESEJAHTERAAN SOSIAL ANAK (LKSA) AL-KAUTSAR LEMBANG KABUPATEN BANDUNG BARAT
Authors: Sholihah Mu'alimatus , Kardeti Denti , Subardhini Meiti 
Published: July 2020

Abstract. Attachment refers to a relationship or emotional bonding that last for a long time, intertwined between individuals and attachment figures that are characterized by a desire to seek and maintain closeness to the attachment figures, especially in pressure time. This research aims to gain the empirical description about warmth of children to caregivers. The method in this research uses descriptive method with a quantitative approach. Sampling in this research is census, and data collection technique uses: 1) questionnaire, 2) interview, 3) observation, and 4) documentation study. As for the measuring instrument validity test uses face validity. Furthermore, the result analysed through quantitative and qualitative analysis. The result shows that the attachment quality of children to caregivers in Al-Kautsar’s Children Welfare Institution Lembang, West Bandung Regency is in moderate category. Therefore, it is necessary to make an improvement throught the proposed program which is EDUFAS (Education and Fun Sharing) “Improvement of The Attachment Quality of Children to Caregivers in Al-Kautsar’s Children Welfare Institution Lembang, West Bandung Regency”. Abstrak. Kualitas kelekatan (attachment) merujuk pada ikatan emosional yang bertahan dalam waktu yang lama, terjalin antara individu dengan figur lekatnya yang ditandai adanya keinginan untuk mencari dan memelihara kedekatan dengan figur lekat tersebut terutama pada saat-saat yang menekan. Penelitian ini bertujuan untuk mendapatkan gambaran empiris tentang kehangatan (warmth) anak dengan pengasuh. Metode penelitian yang digunakan dalam penelitian adalah metode kuantitatif dengan pendekatan deskriptif. Teknik penarikan sampel dalam penelitian ini adalah sensus, yaitu dengan jumlah responden sebanyak 38 anak. Teknik pengumpulan data yang digunakan adalah: 1) kuesioner, 2) wawancara tidak terstruktur, 3) observasi, dan 4) studi dokumentasi. Adapun uji validitas alat ukur menggunakan validitas muka (face validity). Selanjutnya hasil penelitian dianalisis menggunakan analisis kuantitatif dan kualitatif. Hasil penelitian menunjukkan bahwa kualitas kelekatan anak dengan pengasuh di Lembaga Kesejahteraan Sosial Anak Al-Kautsar Lembang Kabupaten Bandung Barat termasuk dalam kategori sedang. Begitu pula pada semua aspek dalam kualitas kelekatan termasuk dalam kategori sedang. Maka dari itu diperlukan upaya peningkatan melalui program yang diusulkan yaitu EDUFAS (Educating and Fun Sharing) “Peningkatan Kualitas Kelekatan Anak dengan Pengasuh di Lembaga Kesejahteraan Sosial Anak (LKSA) Al-Kautsar Lembang Kabupaten Bandung Barat”.
COVID-19 Disease Severity Risk Factors for Pediatric Patients in Italy
Authors: Bellino Stefania , Punzo Ornella , Rota Maria Cristina , Del Manso Martina , Urdiales Alberto Mateo , Andrianou Xanthi , Fabiani Massimo , Boros Stefano , Vescio Fenicia , Riccardo Flavia , Bella Antonino , Filia Antonietta , Rezza Giovanni , Villani Alberto , Pezzotti Patrizio ,   COVID-19 WORKING GROUP
Published: July 2020

OBJECTIVES:
To describe the epidemiological and clinical characteristics of coronavirus disease (COVID-19) pediatric patients aged &lt;18 years in Italy.

METHODS:
Data from the national case-based surveillance system of confirmed COVID-19 infections until May 8, 2020, were analyzed. Demographic and clinical characteristics of subjects were summarized by age groups (0–1, 2–6, 7–12, 13–18 years), and risk factors for disease severity were evaluated by using a multilevel (clustered by region) multivariable logistic regression model. Furthermore, a comparison among children, adults, and elderly was performed.

RESULTS:
Pediatric patients (3836) accounted for 1.8% of total infections (216 305); the median age was 11 years, 51.4% were male, 13.3% were hospitalized, and 5.4% presented underlying medical conditions. The disease was mild in 32.4% of cases and severe in 4.3%, particularly in children ≤6 years old (10.8%); among 511 hospitalized patients, 3.5% were admitted in ICU, and 4 deaths occurred. Lower risk of disease severity was associated with increasing age and calendar time, whereas a higher risk was associated with preexisting underlying medical conditions (odds ratio = 2.80, 95% confidence interval = 1.74–4.48). Hospitalization rate, admission in ICU, disease severity, and days from symptoms onset to recovery significantly increased with age among children, adults and elderly.

CONCLUSIONS:
Data suggest that pediatric cases of COVID-19 are less severe than adults; however, age ≤1 year and the presence of underlying conditions represent severity risk factors. A better understanding of the infection in children may give important insights into disease pathogenesis, health care practices, and public health policies.
‘Where no man has gone before!’ – Exploring new knowledge in design-based research projects: A treatise on phenomenology in design studies
Authors: Sloane Peter F. E. 
Published: July 2020

Design-based research (DBR) is a programme where researchers co-operate with practitioners to work out new solutions. In DBR researchers interfere in daily life and participate in practitioners’ working processes. One open question is: What kind of knowledge can be generated in these projects? My starting point here is a DBR project in vocational education and training in Germany which is used for an investigation of the epistemological background of this kind of research enterprise. The characteristics of DBR are reflected on the basis of phenomenological and hermeneutical approaches. The basic assumptions of these concepts are introduced and applied to the DBR approach to show how DBR generally works and how, specially, features of DBR like participation in daily life, co-operation with practitioners, gathering knowledge in the field a. s. o. can be handled.
The line of argumentation in this contribution is a radical switch between practical questions in daily work in DBR on one hand and theoretical re-assurance on the other hand. For researchers, DBR is an enterprise in a new world. The analytical paradigm does not prepare the voyagers for this journey. Therefore the non-analytic continental tradition of philosophy has to be re-discovered.
Playing with rusty nails: ‘Conceptual tinkering’ for ‘next’ practice
Authors: Leonard Simon N. , Belling Sarah , Morris Alexandra , Reynolds Eva 
Published: July 2020

An important issue for the Educational Design Research (EDeR) community to continue to deal with is the scalable and sustainable implementation of its methods, findings and designs beyond the bounds of specific projects. Those engaged in EDeR specifically seek out concurrent problems of theory and problems of practice, but this should not be seen as sufficient for ensuring their work has impact beyond their current project. Just as with other forms of research, EDeR practitioners must still reach out to and connect with educational institutions and teachers who are dealing with many competing demands.
This position paper offers a largely theoretical contribution to the discussion of the problem of implementation. It will introduce the concept of conceptual tinkering as an approach to engaging teachers in the skillsets and, more importantly, the mindsets of EDeR as an approach to educational improvement. Sketches and prototypes of tools to enable conceptual tinkering will be discussed.