bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early indirect impact of COVID-19 pandemic on utilization and outcomes of reproductive, maternal, newborn, child and adolescent health services in Kenya
Authors: Shikuku Duncan , Nyaoke Irene , Gichuru Sylvia , Maina Onesmus , Eyinda Martin , Godia Pamela , Nyaga Lucy , Ameh Charles 
Published: September 2020

AbstractBackgroundThe COVID-19 global pandemic is expected to result in 8.3–38.6% additional maternal deaths in many low-income countries. The objective of this paper was to determine the initial impact of COVID-19 pandemic on reproductive, maternal, newborn, child and adolescent health (RMNCAH) services in Kenya.MethodsData for the first four months (March-June) of the pandemic and the equivalent period in 2019 were extracted from Kenya Health Information System. Two-sample test of proportions for hospital attendance for select RMNCAH services between the two periods were computed.ResultsThere were no differences in monthly mean (±SD) attendance between March-June 2019 vs 2020 for antenatal care (400,191.2±12,700.0 vs 384,697.3±20,838.6), hospital births (98,713.0±4,117.0 vs 99,634.5±3,215.5), family planning attendance (431,930.5±19,059.9 vs 448,168.3±31,559.8), post-abortion care (3,206.5±111.7 vs 448,168.3±31,559.8) and pentavalent 1 immunisation (114,701.0±3,701.1 vs 110,915.8±7,209.4), p>0.05. However, there were increasing trends for adolescent pregnancy rate, significant increases in FP utilization among young people (25.7% to 27.0%), injectable (short-term) FP method uptake (58.2% to 62.3%), caesarean section rate (14.6% to 15.8%), adolescent maternal deaths (6.2% to 10.9%) and fresh stillbirths (0.9% to 1.0%) with a reduction in implants (long-term) uptake (16.5% to 13.0%) (p< 0.05). No significant change in maternal mortality ratio between the two periods (96.6 vs 105.8/100,000 live births, p = 0.1023) although the trend was increasing.ConclusionCOVID-19 may have contributed to increased adolescent pregnancy, adolescent maternal death and stillbirth rates in Kenya. If this trend persists, recent gains achieved in maternal and perinatal health in Kenya will be lost. With uncertainty around the duration of the pandemic, strategies to mitigate against catastrophic indirect maternal health outcomes are urgently needed.
Alleviation of neuropathic pain by over-expressing a soluble colony-stimulating factor 1 receptor
Authors: Gushchina Svetlana , Yip Ping K. , Parry Glesni A. , Sivakumar Haripriya , Li Jie , Liu Min , Bo Xuenong 
Published: September 2020

AbstractIn this study, we aim to alleviate neuropathic pain by suppressing microgliosis and macrophage accumulation, which is achieved by over-expressing a non-functional soluble colony-stimulating factor 1 receptor using adeno-associated virus 9 vectors (AAV9/sCSF1R). AAV9/sCSF1R and AAV9/GFP were intrathecally administered into mouse lumbar spine. Two weeks later, these mice underwent partial sciatic nerve ligation to induce neuropathic pain. GFP and sCSF1R were highly expressed in dorsal root ganglia (DRG) and spinal cords in AAV9-injected mice. Nerve ligation alone or pre-treated with AAV9/GFP led to significant microgliosis in the lumbar spinal cords and macrophage accumulation in DRG and sciatic nerves. In nerve-ligated mice pre- treated with AAV9/sCSF1R the microglia densities in the dorsal and ventral horns and macrophage densities in DRG and sciatic nerves were significantly lower compared to nerve-ligated mice pre-treated with AAV9/GFP. Behavioural tests showed that nerve-ligated mice pre- treated with AAV9/sCSF1R had a significantly higher paw withdrawal threshold, indicating the alleviation of neuropathic pain. The results implicate that viral vector-mediated expression of sCSF1R may represent a novel strategy in long-term alleviation of neuropathic pain.
Overconfidence in visual perception in Parkinson’s disease
Authors: Halperin Orly , Karni Roie , Israeli-Korn Simon , Hassin-Baer Sharon , Zaidel Adam 
Published: September 2020

AbstractBackgroundIncreased dependence on visual cues in Parkinson’s disease (PD) can unbalance the perception-action loop, impair multisensory integration, and affect everyday function of PD patients. It is currently unknown why PD patients seem to be more reliant on their visual cues.ObjectivesWe hypothesized that PD patients may be overconfident in the reliability (precision) of their visual cues. In this study we tested coherent visual motion perception in PD, and probed subjective (self-reported) confidence in their visual motion perception.Methods20 patients with idiopathic PD, 21 healthy aged-matched controls and 20 healthy young adult participants were presented with visual stimuli of moving dots (random dot kinematograms). They were asked to report: (1) whether the aggregate motion of dots was to the left or to the right, and (2) how confident they were that their perceptual discrimination was correct.ResultsVisual motion discrimination thresholds were similar (unimpaired) in PD compared to the other groups. By contrast, PD patients were significantly overconfident in their visual perceptual decisions (p=0.002 andp<0.001 vs. the age-matched and young adult groups, respectively).ConclusionsThese results suggest intact visual motion perception, but overestimation of visual cue reliability, in PD. Overconfidence in visual (vs. other, e.g., somatosensory) cues could underlie accounts of increased visual dependence and impaired multisensory integration in PD, and could contribute to gait and balance impairments. Future work should investigate PD confidence in somatosensory function. A better understanding of altered sensory reliance in PD might open up new avenues to treat debilitating symptoms.
ErbB dysregulation impairs cognition via myelination-dependent and - independent oligodendropathy
Authors: Hu Xu , Xiao Guanxiu , He Li , Zhu Qingyu , Niu Xiaojie , Li Huashun , Xu Qi , Wei Zhengdong , Huang Hao , Luan Yifei , Qiu Mengsheng , Tanaka Kenji F. , Shen Ying , Tao Yanmei 
Published: September 2020

AbstractWhite matter abnormalities are an emerging pathological feature of schizophrenia. However, their attributions to the disease remain largely elusive. ErbB receptors and their ligands, some of which are essential for peripheral myelination, confer susceptibility to schizophrenia. By synergistically manipulating ErbB receptor activities in a oligodendrocyte-stage-specific manner in mice after early development, we demonstrate the distinct effects of ErbB signaling on oligodendrocytes at various differentiation states. ErbB overactivation, in mature oligodendrocytes, induces necroptosis causing demyelination, whereas in oligodendrocyte precursor cells, induces apoptosis causing hypomyelination. In contrast, ErbB inhibition increases oligodendrocyte precursor cell proliferation but induces hypomyelination by suppressing the myelinating capabilities of newly-formed oligodendrocytes. Remarkably, ErbB inhibition in mature oligodendrocytes diminishes axonal conduction under energy stress and impairs working memory capacity independently of myelin pathology. This study reveals the etiological implications of oligodendrocyte vulnerability induced by ErbB dysregulation, and elucidates the pathogenetic mechanisms for variable structural and functional white matter abnormalities.
Domestic waste policy in Ireland – economization and the role of accounting
Authors: Quinn Martin , Feeney Orla 
Published: September 2020

PurposeThis paper examines how accounting concepts were utilised in domestic waste collection services in Ireland over the past two decades or so. In comparison to other former “free” services in the Irish context, the prevalence of accounting concepts has been greater and delivered a more successful outcome.Design/methodology/approachDrawing on the concepts of calculation, the “economic” and economization, events around domestic waste policy in Ireland are examined, and the increasing prevalence of concepts such as price, cost and profitability in these processes are a focal point. Publicly available documents such as government policy documents, parliamentary records and media reports are utilised to draw out these concepts. The period of analysis is 1996–2018.FindingsThe findings reveal the role of accounting concepts in the economization of domestic waste policy in Ireland. The result of the economization process was a fully privatised, profit-oriented, price-monitored system.Research limitations/implicationsThis research provides a broad view of accounting concepts in the management of domestic waste. It highlights how waste policy in Ireland travelled through instances of being political and economic over time. The research is limited by its use of secondary data.Originality/valueThis study highlights how accounting concepts were used in varying ways to bring about a satisfactory solution to domestic waste disposal in Ireland, namely the privatisation of waste services.
Contribution of prejudiced clustering education system in developing horizontal and vertical mismatch in job market: quality of employees in banking sector
Authors: Alam Gazi Mahabubul , Roslan Samsilah 
Published: September 2020

PurposeEducation system supplies the required manpower in order to ensure the national prosperity. A salient link between education and business sector is a prerequisite to cater economically productive manpower. Economic and social development supplements each other that can only be ensured via a functional education system. A dysfunction education system created by a biased clustering policy develops a greater horizontal and vertical mismatch with the job market in many developing nations. This mismatch dents the quality of business management that halts the national prosperity. Therefore, the role of education has become questionable. This research aims to bridge between education and business sectors.Design/methodology/approachGiven the differentiated nature of research questions, multiple techniques are used to collect the data. However, this research bears the norms of qualitative method. Both secondary and primary data are used. While, secondary data are collected by the banks, Bangladesh Bureau of Educational Information and Statistics (BANBEIS) and by the University Grants Commission (UGC), primary data are collected through interviews. Document review and data collected through personal communication with members of staff of sampled banks and institutes of HE also supplements. Data were collected from six commercial banks and from the Central Bank.FindingsFindings suggest that clustering system favours science graduates by depriving business counterpart, which creates an atmosphere of educational disparity. This disparity affects the symbiotic and reciprocal relationship that exists amongst different provisions (i.e. secondaryand tertiary) of education. Favoured clustering system further contributes for a larger “horizontal educational mismatch” with job market. Therefore, science graduates occupy the places in the banks where business graduates should ideally be employed. Being a dysfunction system, education fails to support substantially for social and economic developments.Originality/valueA few studies are conducted in the area of HE in Bangladesh but none covers the issue of impact of clustering system of education in secondary provision on HE and job market. Graduates' performance in carrying out the jobs is seen as the most important element for the business management. This study has suggested a unique way forward which would be able to reduce the mismatch between education system and job market, enabling a substantial business management process. Considering this, the paper is first on its kind.
Global to small island; a cross-scale foresight scenario exercise
Authors: Drakes Crystal , Cashman Adrian , Kemp-Benedict Eric , Laing Timothy 
Published: September 2020

PurposeThe use of socio-economic scenarios in small island developing states (SIDS) when assessing, and planning for, the impacts of global changes on national socioeconomic and environmental systems is still in its infancy. The research conducts a cross-scale foresight scenario exercise to produce regional scenarios and national storylines for Caribbean islands that are of “partial” consistency to the shared socioeconomic pathways (SSPs) and representative concentration pathways (RCPs) and shows how future socioeconomic and climatic changes can be applied to inform natural resource management decisions.Design/methodology/approachTo develop the scenarios, the study uses a three-staged linking process using mixed methods to “triangulate” each technique to compensate for weaknesses of one method by introducing a complementary method at each stage. A participatory-expert stepwise approach with feedback loops is used and complemented with a climate sensitive tourism water demand model.FindingsFour regional exploratory socio-economic scenarios were constructed that are partially consistent with global scenarios. In addition, national storylines for four island states were developed based on the regional scenarios. Using RCP 4.5 hotel water demand in Barbados is estimated under three of the regional scenarios based on compatibility. The results indicate there is a 17% difference between the highest and lowest estimated water demand, indicating the effect of varying socio-economic conditions on water demand.Originality/valueThe paper contributes to the literature by presenting regional socio-economic scenarios, specifically for SIDS, that are partially consistent with both global climatic RCPs and SSPs using a cross-scale approach. The scenarios are then used to demonstrate how future socio-economic pathways impact on freshwater demand.
Human resource management systems and intellectual capital: is the relationship universal in knowledge-intensive firms?
Authors: Sokolov Dmitri , Zavyalova Elena 
Published: September 2020

PurposeWhile prior research suggests that human resource management (HRM) practices are crucial drivers of a firms' intellectual capital, few studies have tried to deconstruct this relationship and investigate how HRM practices specifically affect intellectual capital resources. Furthermore, prior research treated this relationship as universal and rarely tried to introduce important contingent factors that may alter the mechanisms involved in how HRM practices influence firms' intellectual capital. In this study, the authors examine the relationships between the ability-, motivation- and opportunity-enhancing dimensions of HRM systems and human, social and structural capital and investigate how companies' codification and personalization knowledge management (KM) strategies may alter these relationships.Design/methodology/approachThe data were collected using a telephone survey of 215 knowledge-intensive companies operating in Russia. The paper utilizes partial least squares structural equation modeling (PLS–SEM) to evaluate the measurement model and test hypothesized relationships.FindingsThe findings indicate positive relationships between ability-enhancing practices and firms' human capital between motivation-enhancing practices and firms' human and social capital and between opportunity-enhancing practices and firms' social and structural capital. The authors’ results reveal the limited moderating role of KM strategies in the relationships between HRM and intellectual capital. While a personalization strategy had no impact on any of the proposed relationships, a codification strategy positively moderated the relationship between opportunity-enhancing HRM practices and firms' structural capital.Originality/valueThe study expands the debates in strategic HRM literature by looking “inside” the HRM–intellectual capital relationship. Additionally, the authors’ findings reveal the complexity of the contingent effect that KM strategies of codification and personalization have on the relationship between HRM practices and intellectual capital. Although some of the relationships were not moderated by the KM strategy of the firm, the HRM–intellectual capital relationship cannot be considered fully universal.
Distributed manufacturing: a new form of localised production?
Authors: Srai Jagjit Singh , Graham Gary , Hennelly Patrick , Phillips Wendy , Kapletia Dharm , Lorentz Harri 
Published: September 2020

PurposeThe emergence of distributed manufacturing (DM) is examined as a new form of localised production, distinct from previous manifestations of multi-domestic and indigenous production.Design/methodology/approachSupply network (SN) configuration and infrastructural provisioning perspectives were used to examine the literature on established localised production models as well as DM. A multiple case study was then undertaken to describe and explore the DM model further. A maximum variation sampling procedure was used to select five exemplar cases.FindingsThree main contributions emerge from this study. First, the research uniquely brings together two bodies of literature, namely SN configuration and infrastructure provisioning to explore the DM context. Second, the research applies these theoretical lenses to establish the distinctive nature of DM across seven dimensions of analysis. Third, emerging DM design rules are identified and compared with the more established models of localised production, drawing on both literature and DM case evidence.Practical implicationsThis study provides a rich SN configuration and infrastructural provisioning view on DM leading to a set of design rules for DM adoption, thus supporting practitioners in their efforts to develop viable DM implementation plans.Originality/valueThe authors contribute to the intra- and inter-organisational requirements for the emerging DM context by providing new perspectives through the combined lenses of SN configuration and infrastructural provisioning approaches.
Which future path to pick? A contingency approach to omnichannel warehouse configuration
Authors: Kembro Joakim Hans , Norrman Andreas 
Published: September 2020

PurposeRecent studies have highlighted the importance of adopting a contingency approach to configuring omnichannel warehouses. Nonetheless, research on how various contextual factors influence the selection of warehouse configuration is scarce. This study fills this knowledge gap by exploring how and why certain configurations fit in different omnichannel contexts.Design/methodology/approachA case study is conducted with six leading Swedish omnichannel retailers. Focusing on outbound warehouse configurations, data are collected through interviews, on-site observations, and secondary sources. A multistep analysis is made, including both pattern matching and explanation building.FindingsThe qualitative analysis reveals 16 contextual factors, of which assortment range, requested online order fulfillment times, goods size and total transactions are the most influential. The study shows how contextual factors create different challenges, thereby influencing the choice of the configurations. In addition to market dynamics and task complexity, the study describes four categories of the factors and related challenges that are particularly important in omnichannels: speed, space, economies of scale and tied-up capital.Research limitations/implicationsThe findings highlight the importance of understanding context and imply that multiple challenges may require trade-offs when selecting configurations, for example, regarding what storage, processes and resources to integrate or separate. To confirm, extend, challenge and further operationalize the ideas and observations put forward in this paper, an agenda with future research issues is given for this accelerating, contemporary phenomenon.Practical implicationsManagers could leverage the frameworks proposed for the contextual profiling of their current and future positions. The frameworks provide support for understanding the important challenges and potential trade-offs and developing aligned configurations.Originality/valueThis study is original in the way it provides in-depth, case study findings about contextual factors and their influence on omnichannel warehouse configuration.
Sampling-based estimation method for parameter estimation in big data business era
Authors: Alim Abdul , Shukla Diwakar 
Published: September 2020

PurposeThis paper aims to present sample-based estimation methodologies to compute the confidence interval for the mean size of the content of material communicated on the digital social media platform in presence of volume, velocity and variety. Confidence interval acts as a tool of machine learning and managerial decision-making for coping up big data.Design/methodology/approachRandom sample-based sampling design methodology is adapted and mean square error is computed on the data set. Confidence intervals are calculated using the simulation over multiple data sets. The smallest length confidence interval is the selection approach for the most efficient in the scenario of big data.FindingsResultants of computations herein help to forecast the future need of web-space at data-centers for anticipation, efficient management, developing a machine learning algorithm for predicting better quality of service to users. Finding supports to develop control limits as an alert system for better use of resources (memory space) at data centers. Suggested methodologies are efficient enough for future prediction in big data setup.Practical implicationsIn IT sector, the startup with the establishment of data centers is the current trend of business. Findings herein may help to develop a forecasting system and alert system for optimal decision-making in the enhancement and share of the business.Originality/valueThe contribution is an original piece of thought, idea and analysis, deriving motivation from references appended.
COVID-19. Scenarios of a superfluous crisis
Authors: Roth Steffen , Clausen Lars , Möller Sören 
Published: September 2020

Purpose
This study aims to highlight the critical role case fatality rates (CFR) have played in the emergence and the management of particularly the early phases of the current coronavirus crisis.

Design/methodology/approach
The study presents a contrastive map of CFR for the coronavirus (SARS-CoV-2) and influenza (H1N1 and H2N2).

Findings
The mapped data shows that current CFR of SARS-CoV-2 are considerably lower than, or similar to those, of hospitalised patients in the UK, Spain, Germany or international samples. The authors therefore infer a possible risk that the virulence of the coronavirus is considerably overestimated because of sampling biases, and that increased testing might reduce the general CFR of SARS-CoV-2 to rates similar to, or lower than, of the common seasonal influenza.

Originality/value
This study concludes that governments, health corporations and health researchers must prepare for scenarios in which the affected populations cease to believe in the statistical foundations of the current coronavirus crisis and interventions.