bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond knowledge acquisition: multilevel factors influencing family planning utilization among women in conservative communities in Rural Burundi.
Authors: HAKIZIMANA SONIA , Odjidja Emmanuel Nene 
Published: April 2020

Abstract
BackgroundWith a fertility rate of 5.5 children per woman, Burundi has been ranked as fourth highest country with the highest fertility rate in the world. Family planning is known to allow couples to achieve the desired family size, appropriate space birth and the limitation of pregnancies. Also, family planning can contribute to mitigating some health issues such as unintended pregnancies and abortions all of which, are often associated with multi-parity. In conservative community in rural Burundi, knowledge on family planning is high and such services are free yet utilisation is low. Employing a mixed methods, this study first quantifies contraceptive prevalence and second, explore the contextual multilevel factors associated with low family planning utilisation MethodsAn explanatory sequential mixed study was conducted. Five hundred and thirty women in union were interviewed using structured and pre-tested questionnaire. Next, 11 focus group discussions were held with community members (n=132). The study was conducted in eighteen collines of two health districts of Vyanda and Rumonge in provinces of Bururi and Rumonge respectively. Quantitative data was analysed with SPSS and qualitative data was coded and deductive thematic methods were applied to find themes and codes.ResultsThe overall contraceptive prevalence was 22.6%. Injectables (40%), Implants (24.6%), Male condom (10.8%) and pills (6.2%) were the major contraceptive methods utilized by study participants. Natural contraceptive methods were used by 13.8% of women interviewed. The reasons for not using modern contraceptive methods were side effects (51%), perceived postpartum (18.8%), religious beliefs (12.9%), partner’s opposition (8.4%), partner absenteeism (6.4%) and lack of awareness (2.5%). The qualitative component identified fear of side effects, religious beliefs, cultural barriers, spousal communication gap and refusal of family planning services by health practitioners as factors.ConclusionThe study suggests that low uptake of family planning can be attributed to perceived or experienced side effects as well as deeply rooted negative beliefs which are reinforced by religious beliefs. Men and religious leaders’ involvement in family planning initiatives can positively impact behaviour change and increase family planning acceptance.
Dynamics Modeling of Corneal Deformation under Air Puﬀ with Linear and Nonlinear Viscoelastic Model
Authors: Kim Jong Ryeol , Ko Match Wai Lun , Zhalgas Aidana , Wei Dongming 
Published: April 2020

Abstract
Background: The aim of the study is to model the corneal dynamic deformation under an air puﬀ excitation. The deformation response of the cornea was modeled by using linear and nonlinear viscoelastic models. The corneal deformation responses generated from the linear and nonlinear viscoelastic model were correlated with the clinical results, which were obtained from Corneal Visualization Scheimpﬂug Tonometer (Corvis ST) to evaluate the comparable biomechanical parameters of the cornea. Methods: A prompt deformation occurs when the external force applied to the cornea. Then a continuous deformation follows. A simple mass, spring and dashpot system were used to model human eyeball. Results: In linear viscoelastic model, the corneal elastic stiﬀness commanded behavior of the corneal deformation and its maximum, when the viscous component aﬀected for its lateral shifting and marginally alter the magnitude.Whereas, in the nonlinear viscoelastic model, the corneal material nonlinearity commanded the behavior and maximum of the corneal deformation, while the viscous component marginally contributed for its lateral shifting and demonstrated the minimum aﬀect on the magnitude and form. A multi-objective genetic algorithm-based optimization procedure was used to identify the material properties in the nonlinear viscoelastic model for 29 eyes of 20 normal people. Conclusion: The corneal deformation response model with nonlinear viscoelastic model showed to have a better ﬁt with the corneal dynamic deformation behavior under an air pulse excitation. The biomechanical properties of the cornea in vivo can be evaluated by using and analysing dynamic deformation of the cornea under an air puﬀ excitation model.
A Numerical Study of Wind Turbine Airfoil Combined Oscillations Considering Phase Difference under Yaw Loads
Authors: Yin Yufeng , Ji Zhengjie , Zhang Jin , Yin Xuan , Feng Yijie , Liu Peishan 
Published: April 2020

Abstract
In order to further improve the operating efficiency of wind turbines and explore the aerodynamic performance of the complex motion of wind turbine blades under yaw loads. In this study, the change in the angle of attack of the blade section airfoil under yaw load can be modeled as an oscillating airfoil and combined with the blade's flapwise motion. The NREL S809 airfoil are chosen for the research, based on the SST k-ω turbulence model with transition correction, under the condition of Reynolds number of 10 6 . The effect of phase difference on its aerodynamic performance under combined flapwise and pitching motion in various flapwise amplitudes and working conditions were analyzed. For the combined oscillations, the effects of the flapwise amplitude ( h ) in the range of 0.2≤ h ≤0.5 are investigated with the phase differences of Φ=±3π/4, ±π/2, ±π/4, 0. The results show that the phase difference between the pitching motion and the flapping motion and the different flapping amplitudes can have a large impact on the aerodynamic performance of the airfoil during dynamic stall, but the degree of influence is greatly different in different situations.
Impact of metastatic lymph nodes on survival in well and moderately differentiated appendiceal neuroendocrine tumors: whether current “lymph node-decided” surgical strategy benefits?
Authors: Lin Haiping , Wang Liyuan , Bai Yang , Yu Shian 
Published: April 2020

Abstract
Background Current guidelines recommended right hemicolectomy for appendiceal neuroendocrine tumors (A-NETs) patients with lymph node (LN) metastasis. Prognoses of these patients are favorable, and the prognostic impact of metastatic LN is controversial.Objective The study aims to evaluate the prognostic factors of well and moderately differentiated A-NETs, and explore whether right hemicolectomy/ more extended procedure (RHCM) improves prognosis compared to less extended than right hemicolectomy (LRHC).Methods The Fine-Gray proportional hazards model was established to calculate subdistribution hazard ratios of prognostic factors. A propensity score matching was performed to balance intergroup differences between the LRHC and RHCM groups. Survival difference between the after-matched groups was tested using the Gray test, and subgroup analyses were conducted.Results In the multivariate analysis, age, race, histological type and distant metastatic status were associated with prognosis, while tumor size and nodal status were not. After propensity score matching, the patients’ characteristics were well balanced. RHCM did not confer survival advantage in the whole after-matched patients or any subgroup.Conclusions Metastatic LN does not significantly impact prognosis, and RHCM fails to improve prognosis compared to LRHC. Therefore, the current “LN-decided” surgical procedure may not be suitable for patients with well and moderately differentiated A-NETs.
Case report: A bulla mistaken for a pneumothorax
Authors: Aujayeb Avinash 
Published: April 2020

Abstract
Introduction:Vanishing lung syndrome, also known as giant bullous emphysema is a condition usually reported in young male thin smokers. There are numerous case reports that have added to the body of evidence. There are also case reports of the giant bulla being misinterpreted for a pneumothoraxCase report:A 61 year old male with severe chronic obstructive lung disease presented to Accident and Emergency with progressive breathlessness. A chest radiograph showed a giant right sided bulla that was initially misinterpreted as a tension pneumothorax. Further review of his imaging and lung function pointed to him having vanishing lung syndrome. He was referred for a cardiothoracic opinion but was eventually managed conservatively.Discussion:Vanishing lung syndrome is characterised by a slowly enlarging upper lobe bulla that compresses normal lung parenchyma and causes mediastinal shift, with the patients experiencing increasing dyspnoea and reduced exercise tolerance. Smoking cessation is the mainstay of treatment. If they are relatively asymptomatic, patients are managed conservatively. Otherwise a variety of lung volume reduction techniques can be consideredConclusion:A large bulla can look the same as a pneumothorax but the former does not have a lung edge and has a more rounded appearance. A CT scan is very useful in differentiating between the two pathologies. Bullae are predominantly caused by smoking. Bullae will cause high total lung volumes and residual volumes, but low alveolar volumes. Bullae can be observed or treated by surgical techniques
Integrative multi-omics analysis reveals the landscape of Cyclin-Dependent Kinase (CDK) family genes in pan-cancer
Authors: Chen Erlin , Bian Saiyan , Ni Wenkai , Wang Peng , Wang Feiran 
Published: April 2020

Abstract
Cyclin-Dependent Kinases (CDKs) get widely involved in cancer development. However, A wealth of conflicting data raise the question whether CDKs serve as oncogenes or cancer suppressors. Here, we integrate multi-omics analysis to explore the core genes of CDK family across multiple cancer types. To our surprise, CDKs are overexpressed in a wide range of cancers, where heterozygous amplification contributed to such transcriptional dysregulation. To explore the functional impact of such overexpression, further pathway analysis revealed that CDK genes cancer hallmarks such as apoptosis and cell cycle. CDK expression associates with 58 drug sensitivity including Trametinib and I-BET-762. Taken together, our study define the landscape of CDKs in a system level and open potential therapeutic opportunities for cancer patients.
Perpaduan Cakrawalamu dan Cakrawalaku: Hermeneutik Gadamer dan Sumbangsihnya bagi Pendidikan Teologi di Indonesia
Authors: Simanjuntak Wilda 
Published: April 2020

AbstractReading messages from the past to fi nd their implications for the present is a difficult task of interpretation. Certain hermeneutical skills are needed to prevent failure to bridge the gap in perspective between writers andreaders, and to meet the contextual needs. The focus of this article is the framework of Hans-Georg Gadamer’s hermeneutic theory. Studying Gadamer provides important benefits for contextual hermeneutic studies. This article suggests that Gadamer’s hermeneutics is beneficial for theological education struggling to overcome the diversity of horizons in the process of discovering the meaning of scriptures.
AbstrakMembaca pesan dari masa lalu, menemukan implikasinya bagi masa sekarang adalah tugas memaknai yang tidak mudah. Dibutuhkan keterampilan hermeneutis tertentu untuk mencegah kegagalan menjembatani kesenjangan cara pandang yang ada di antara penulis dan pembaca, dan memenuhi kebutuhan lingkungan yang kontekstual. Fokus artikel ini adalah kerangka teori hermeneutik Hans-Georg Gadamer. Hasil studi terhadap Gadamer ini memberi manfaat penting bagi studi hermeneutik dalam semangatnya mencarimakna yang kontekstual. Studi ini menyarankan bahwa hermeneutik Gadamer bermanfaat bagi pendidikan teologi yang selalu bergumul mengatasi kepelbagaian horizon dalam proses menemukan makna Kitab Suci.
Rehabilitación neuropsicológica en niños con TDAH: ¿Qué dice la evidencia sobre el entrenamiento neurocognitivo?
Authors: Fernández Martha 
Published: April 2020

Los programas de entrenamiento cerebral son cada vez más populares entre los niños. El objetivo general del estudio fue realizar una revisión sistemática sobre el entrenamiento cognitivo en niños con TDAH. Metodología: Se realizó una búsqueda en PubMed, Web of Science, EBSCO, ELSEVIER, ERIC, SciELO, Redalyc, PsycINFO, MEDLINE, DOAJ, Latindex y Dialnet. Ademas en buscadores como Google Académico. Los documentos debían estar publicados entre 2013 hasta 2018. Por cada programa de entrenamiento neurocognitivo se acordó un tope de 50 estudios y la población objeto de estudio fue niños y adolescentes con TDAH. Resultados: La mayoría de los estudios sobre entrenamiento neurocognitivo informan que el Cogmed, Lumosity, Learning Rx, CogniFit, TDAH Kids Trainer, BrainHQ, Captain’s Log Mind Power Builder, Engage, ETAM, Jungle Memory, MeMotiva Junior y TEAMS son de gran utilidad, siendo los 5 primeros los más empleados, seis de los cuales se dirigen al entrenamiento neurocognitivo de niños con TDAH. Conclusiones: Hace falta evidencia científica que respalde la utilidad de los programas de entrenamiento neurocognitivo en niños con TDAH.
Catalytic Longevity of Hierarchical SAPO-34/AlMCM-41 Nanocomposite Molecular Sieve In Methanol-to-Olefins Process
Authors: Roohollahi Hossein , Halladj Rouein , Askari Sima 
Published: April 2020

Introduction:
SAPO-34/AlMCM-41, as a hierarchical nanocomposite molecular sieve was
prepared by sequential hydrothermal and dry-gel methods studied for catalytic conversion of methanol
to light olefins. Pure AlMCM-41, SAPO-34, and their physical mixture were also produced and
catalytically compared. Physicochemical properties of materials were mainly investigated using XRD,
N2 isothermal adsorption-desorption, FESEM, FT-IR, NH3-TPD, and TG/DTG/DTA techniques.

Methods:
Micro-meso hierarchy of prepared composite was demonstrated by XRD and BET analyses.
Catalytic performance of materials illustrated that the methanol conversion of the prepared composite
was about 98% for 120 min, showing a higher activity than the other catalysts. The initial reaction
selectivity to light olefins of the composite was also comparable with those for the other catalysts.
Furthermore, the results revealed that SAPO-34/AlMCM-41 preparation decreased the concentration
and strength of active acid sites of the catalyst which could beneficially affect the deposition of heavy
molecular products on the catalyst. However, as observed, the prepared composite was deactivated in
olefins production faster than pure SAPO-34.

Results:
The small mean pore diameter of composite could be mainly responsible for its pore blockage
and higher deactivation rate. Meanwhile, since the SAPO-34 prepared by dry-gel method had
inherently high mesoporosity, the AlMCM-41 introduction did not promote the molecular diffusion in
the composite structure.

Conclusion:
The coke content was found 15.5% for deactivated composite smaller than that for the SAPO-
34 catalyst which could be due to the pore blockage and deactivation of the composite in a shorter period.
A Sequence-Based Predictor of Zika Virus Proteins Developed by Integration of PseAAC and Statistical Moments
Authors: Hussain Waqar , Rasool Nouman , Khan Yaser D. 
Published: April 2020

Background:
IKV has been a well-known global threat, which hits almost all of the
American countries and posed a serious threat to the entire globe in 2016. The first outbreak of
ZIKV was reported in 2007 in the Pacific area, followed by another severe outbreak, which
occurred in 2013/2014 and subsequently, ZIKV spread to all other Pacific islands. A broad
spectrum of ZIKV associated neurological malformations in neonates and adults has driven this
deadly virus into the limelight. Though tremendous efforts have been focused on understanding the
molecular basis of ZIKV, the viral proteins of ZIKV have still not been studied extensively.

Objectives:
Herein, we report the first and the novel predictor for the identification of ZIKV proteins.

Methods:
We have employed Chou’s pseudo amino acid composition (PseAAC), statistical
moments and various position-based features.

Results:
The predictor is validated through 10-fold cross-validation and Jackknife testing. In 10-
fold cross-validation, 94.09% accuracy, 93.48% specificity, 94.20% sensitivity and 0.80 MCC
were achieved while in Jackknife testing, 96.62% accuracy, 94.57% specificity, 97.00% sensitivity
and 0.88 MCC were achieved.

Conclusion:
Thus, ZIKVPred-PseAAC can help in predicting the ZIKV proteins efficiently and
accurately and can provide baseline data for the discovery of new drugs and biomarkers against ZIKV.
Biochemical and Computational Approaches for the Large-Scale Analysis of Protein Arginine Methylation by Mass Spectrometry
Authors: Musiani Daniele , Massignani Enrico , Cuomo Alessandro , Yadav Avinash , Bonaldi Tiziana 
Published: April 2020

The absence of efficient mass spectrometry-based approaches for the large-scale analysis of protein arginine methylation has hindered the understanding of its biological role, beyond the transcriptional regulation occurring through histone modification. In the last decade, however, several technological advances of both the biochemical methods for methylated polypeptide enrichment and the computational pipelines for MS data analysis have considerably boosted this research field, generating novel insights about the extent and role of this post-translational modification.Here, we offer an overview of state-of-the-art approaches for the high-confidence identification and accurate quantification of protein arginine methylation by high-resolution mass spectrometry methods, which comprise the development of both biochemical and bioinformatics methods. The further optimization and systematic application of these analytical solutions will lead to ground-breaking discoveries on the role of protein methylation in biological processes.
Active Immunotherapy with 12-mer Aβ1-42-like Assembly Vaccine Shows Efficacy in Aged 3×Tg-AD Mice
Authors: Fang Hao , Zhou Guo , Li Qingli , Wang Haichao , Pang Xiaobin , Xu Qing , Yu Yunzhou 
Published: April 2020

Background:
Alzheimer's disease (AD) is the most common progressive
neurodegenerative disorder characterized by senile plaques and neurofibrillary tangles
(NFTs). The amyloid-oligomer hypothesis indicates that the buildup of toxic oligomers in
vivo is likely to impair memory and synaptic function.

Methods:
In our study, a kind of novel recombinant chimeric 12×(Aβ1-15-Th) antigen
was developed as 12-mer Aβ1-42-like assembly vaccine. We designed this 12×(Aβ1-15-
Th) antigen to mimic the assembly states of Aβ1-42 using twelvefold Aβ1–15 (B cell
epitopes of human Aβ1-42) and foreign human T helper (Th) epitopes (as the T cell
epitopes of Aβ1-42) constructs. Its immunogenicity as a subunit vaccine was tested on
C57/BL6 mice, and the efficacy was shown by applying it to AD mice.

Results:
This 12×(Aβ1-15-Th) vaccine induced robust Aβ-specific antibodies in 3×Tg-
AD and C57/BL6 mice. As early immunotherapeutic agent of AD, the 12×(Aβ1-15-Th)
vaccine significantly improved the behavior performance of aged 3 × Tg-AD mice, and
reduced the levels of soluble Aβ oligomers and soluble Aβ in the brain. In aged 3 × Tg-
AD mice, immunotherapy with the 12×(Aβ1-15-Th) vaccine could prevent Aβ-induced
decrease of synaptic proteins, which suggested that it had neuroprotective effects on the
brain.

Conclusion:
The novel recombinant 12×(Aβ1-15-Th) chimeric vaccine targeting of
pathological conformations of Aβ oligomers has shown obvious neuroprotective benefits
in the preclinical AD model mouse, which indicates that it is a good candidate vaccine
for the prophylaxis of AD.
Chemical Analysis of Traditional Food Additive Dokhora Khar Derived from Water Hyacinth (Eichhornia crassipes)
Authors: Talukdar Anjumani , Deka Dibakar C. 
Published: April 2020

Background:
Dhokora khar (solid alkali), derived from water hyacinth (Eichhornia crassipes)
is used by the people of Assam as a traditional food additive and as an antacid. It is usually
prepared from the aqueous extract of water hyacinth ash. It is very popular in lower Assam particularly
in the district of Barpeta and nearby areas. Apart from its use as a food additive in preparing
palatable dishes, it is also used for the cure of ailments arising from stomach acidity and indigestion.
In rural Assam, this khar finds applications as a natural fertilizer as well as a cleansing agent.

Methods:
Standard chemical and spectral procedures have been used to confirm the presence of acid
and basic radicals. SEM-EDX, Atomic Absorption Spectrometry and Flame Photometry were used
for information on chemical constituents.

Results:
Standard chemical and spectral procedures have been used to confirm the presence of acid
and basic radicals. SEM-EDX, Atomic Absorption Spectrometry and Flame Photometry were used
for information on chemical constituents.

Conclusion:
The investigation suggests that dokhora khar consists of a mixture of carbonates, chlorides,
sulfates and phosphates of various metals such as K, Mg, Ca, Na, Fe, Mn, Zn, Cu, etc. Some of
these metals such as Fe, Co, Mn, Ni, Cu, Zn, Cr, etc., are essential nutrients. Hence the results establish
that the consumption of this traditional food additive by the natives of Assam provides health
benefits.
Study on the Effect of Xylitol and Maltitol as Alternative Sweeteners in Sponge Cakes
Authors: Javanmardi Fardin , Mousavi Mir-Michael , Ghazani Afsaneh T. , Mahmoudpour Mansour , Taram Faran , Pilevar Zahra 
Published: April 2020

Background:
As the main sweetener in sponge cakes, sucrose provides not only energy
and structure, but also acts as a stabilizer and tenderizer. Due to its high-calorie content, alternative
sweeteners such as xylitol and maltitol are used in its place.

Objective:
The purpose of this study is to substitute sugar with xylitol and maltitol in sponge cake.

Methods:
In this study, the possibility of producing sugar free sponge cakes with xylitol and maltitol
was evaluated (control: 100% sucrose, M1: 100% xylitol, M2: 75% xylitol-25% maltitol, M3: 50%
xylitol-50% maltitol and M4: 25% xylitol- 75% maltitol). Sensory evaluations and physicochemical
properties of the final product such as water activity, moisture content, firmness, cake volume, crust
color and sensory analyses were determined.

Results:
Based on the results obtained from the four samples, M3 and M4 resulted in a significant
decrease in volume. The highest specific volume was obtained in M2. The last two samples, M1 and
M2 showed lower water activity than the control. In addition, the highest dark crust color was obtained
in M1. M2 produced a softer texture and thus produced cakes with the highest flavor.

Conclusion:
The results of the study showed that complete substitution of sucrose with 75% xylitol
and 25% maltitol (M2) produced samples with similar crust color, firmness, volume and porosity in
comparison with control cakes.
BOARD OF DIRECTORâ€™S CHARACTERISTICS, INTELLECTUAL CAPITAL, AND BANK PERFORMANCE An empirical examination of Indonesian Banking Sector
Authors: Rositha Annisa Hilmy , Firdausi Nila , Darmawan Ari 
Published: April 2020

Abstract The purpose of this study is to examine the effect of board of directorsâ€™characteristics on intellectual capital and bank performance. This research applies explanatory research with a quantitative approach. The data derived from secondary bank annual report data. The total sample consisted of 12 Indonesian Conventional Banks for a period of 3 years ranging from 2015 to 2017. Partial Least Square (PLS) Analysis is used to analyze the collected data. The results of this study indicated that the board of directorsâ€™ characteristics have a positive and significant influence on intellectual capital. Further testing, the board of directorsâ€™ characteristics has a positive and significant influence on bank performance. Intellectual Capital has a positive and significant influence on bank performance.Â Keyword: Corporate Governance, Board of Directors, Intellectual Capital, BankÂ Â Â Performance, Indonesian Banking