bluuebunny/crossref_metadata_2025_split huggingface dataset:
Altered brain microstructure in association with repetitive subconcussive head impacts and the potential protective effect of jugular vein compression: a longitudinal study of female soccer athletes
Authors: Myer Gregory D , Barber Foss Kim , Thomas Staci , Galloway Ryan , DiCesare Christopher A , Dudley Jonathan , Gadd Brooke , Leach James , Smith David , Gubanich Paul , Meehan III William P , Altaye Mekibib , Lavin Philip , Yuan Weihong 
Published: November 2019

Purpose
To (1) quantify white matter (WM) alterations in female high school athletes during a soccer season and characterise the potential for normalisation during the off-season rest period, (2) determine the association between WM alterations and exposure to repetitive subconcussive head impacts, and (3) evaluate the efficacy of a jugular vein compression collar to prevent WM alterations associated with head impact exposure.

Methods
Diffusion tensor imaging (DTI) data were prospectively collected from high school female soccer participants (14–18 years) at up to three time points over 9 months. Head impacts were monitored using accelerometers during all practices and games. Participants were assigned to a collar (n=24) or non-collar group (n=22). The Tract-Based Spatial Statistics approach was used in the analysis of within-group longitudinal change and between-group comparisons.

Results
DTI analyses revealed significant pre-season to post-season WM changes in the non-collar group in mean diffusivity (2.83%±2.46%), axial diffusivity (2.58%±2.34%) and radial diffusivity (3.52%±2.60%), but there was no significant change in the collar group despite similar head impact exposure. Significant correlation was found between head impact exposure and pre-season to post-season DTI changes in the non-collar group. WM changes in the non-collar group partially resolved at 3 months off-season follow-up.

Discussion
Microstructural changes in WM occurred during a season of female high school soccer among athletes who did not wear the collar device. In comparison, there were no changes in players who wore the collar, suggesting a potential prophylactic effect of the collar device in preventing changes associated with repetitive head impacts. In those without collar use, the microstructural changes showed a reversal towards normal over time in the off-season follow-up period.
Exercise treatment effect modifiers in persistent low back pain: an individual participant data meta-analysis of 3514 participants from 27 randomised controlled trials
Authors: Hayden Jill A , Wilson Maria N , Stewart Samuel , Cartwright Jennifer L , Smith Andrea O , Riley Richard D , van Tulder Maurits , Bendix Tom , Cecchi Francesca , Costa Leonardo O P , Dufour Ninna , Ferreira Manuela L , Foster Nadine E , Gudavalli Maruti R , Hartvigsen Jan , Helmhout Pieter , Kool Jan , Koumantakis George A , Kovacs Francisco M , Kuukkanen Tiina , Long Audrey , Macedo Luciana G , Machado Luciana A C , Maher Chris G , Mehling Wolf , Morone Giovanni , Peterson Tom , Rasmussen-Barr Eva , Ryan Cormac G , Sjögren Tuulikki , Smeets Rob , Staal J Bart , Unsgaard-Tøndel Monica , Wajswelner Henry , Yeung Ella W 
Published: November 2019

BackgroundLow back pain is one of the leading causes of disability worldwide. Exercise therapy is widely recommended to treat persistent non-specific low back pain. While evidence suggests exercise is, on average, moderately effective, there remains uncertainty about which individuals might benefit the most from exercise.MethodsIn parallel with a Cochrane review update, we requested individual participant data (IPD) from high-quality randomised clinical trials of adults with our two primary outcomes of interest, pain and functional limitations, and calculated global recovery. We compiled a master data set including baseline participant characteristics, exercise and comparison characteristics, and outcomes at short-term, moderate-term and long-term follow-up. We conducted descriptive analyses and one-stage IPD meta-analysis using multilevel mixed-effects regression of the overall treatment effect and prespecified potential treatment effect modifiers.ResultsWe received IPD for 27 trials (3514 participants). For studies included in this analysis, compared with no treatment/usual care, exercise therapy on average reduced pain (mean effect/100 (95% CI) −10.7 (−14.1 to –7.4)), a result compatible with a clinically important 20% smallest worthwhile effect. Exercise therapy reduced functional limitations with a clinically important 23% improvement (mean effect/100 (95% CI) −10.2 (−13.2 to –7.3)) at short-term follow-up. Not having heavy physical demands at work and medication use for low back pain were potential treatment effect modifiers—these were associated with superior exercise outcomes relative to non-exercise comparisons. Lower body mass index was also associated with better outcomes in exercise compared with no treatment/usual care. This study was limited by inconsistent availability and measurement of participant characteristics.ConclusionsThis study provides potentially useful information to help treat patients and design future studies of exercise interventions that are better matched to specific subgroups.Protocol publicationhttps://doi.org/10.1186/2046-4053-1-64
Implementation of maternal and perinatal death reviews: a scoping review protocol
Authors: Kinney Mary V , Walugembe David Roger , Wanduru Phillip , Waiswa Peter , George Asha S 
Published: November 2019

IntroductionMaternal and perinatal death surveillance and response (MPDSR), or any related form of audit, is a systematic process used to prevent future maternal and perinatal deaths. While the existence of MPDSR policies is routinely measured, measurement and understanding of policy implementation has lagged behind. In this paper, we present a theory-based conceptual framework for understanding MPDSR implementation as well as a scoping review protocol to understand factors influencing MPDSR implementation in low/ middle-income countries (LMIC).Methods and analysisThe Consolidated Framework for Implementation Research will inform the development of a theory-based conceptual framework for MPDSR implementation. The methodology for the scoping review will be guided by an adapted Arksey and O’Malley approach. Documents will include published and grey literature sourced from electronic databases (PubMed, CINAHL, SCOPUS, Web of Science, JSTOR, LILACS), the WHO Library, Maternal Death Surveillance and Response Action Network, Google, the reference lists of key studies and key experts. Two reviewers will independently screen titles, abstracts and full studies for inclusion. All discrepancies will be resolved by an independent third party. We will include studies published in English from 2004 to July 2018 that present results on factors influencing implementation of MPDSR, or any related form. Qualitative content and thematic analysis will be applied to extracted data according to the theory-based conceptual framework. Stakeholders will be consulted at various stages of the process.Ethics and disseminationThe scoping review will synthesise implementation factors relating to MPDSR in LMIC as described in the literature. This review will contribute to the work of the Countdown to 2030 Drivers Group, which seeks to explore key contextual drivers for equitable and effective coverage of maternal and child health interventions. Ethics approval is not required. The results will be disseminated through various channels, including a peer-reviewed publication.
Central exclusive diffractive production of two-pion continuum at hadron colliders
Authors: Ryutin R. A. 
Published: November 2019

AbstractCalculations of central exclusive diffractive di-pion continuum production are presented in the Regge–eikonal approach. Data from ISR, STAR, CDF and CMS were analyzed and compared with the theoretical description. We also consider theoretical predictions for LHC, possible nuances and problems of calculations and prospects of investigations at present and future hadron colliders.
Conceptions of Masculinity in the Scrolls and the Gendered Emotion of Anger
Authors: Mermelstein Ari 
Published: November 2019

AbstractThis paper considers the sectarian construction of masculinity as it pertains to the emotion of anger. The hegemonic masculinity in antiquity reserves legitimate expressions of anger for men. Sectarian anger, which is a hierarchical emotion bound up in power relations, likewise reflects the sectarian conception of masculinity.The sect’s view of anger approximates Aristotle’s insistence that anger should be limited to certain circumstances and in relation to certain people. Intra-sectarian anger is inappropriate because it endangers the spirit of love or respect for high-status members that should characterize sectarian relations. Anger toward outsiders, however, is not only permitted but expected. The sect’s awareness of the coming “day of vengeance” demands that they align themselves with God by passing judgment on the sinner. By properly calibrating their manliness through the emotion of anger, the sect navigates a fine line between assertions of power and an acknowledgement that their power ultimately is attributable to God.
Afterlife of the Hebrew/Aramaic Component of Judeo-Greek in Non-standard Varieties of Modern Greek
Authors: Krivoruchko Julia G. 
Published: November 2019

Abstract
The article presents fourteen case studies of the Judeo-Greek lexemes of Hebrew and Aramaic origin that have passed into the dialects and sub-standard sociolects of Modern Greek, and aims at improving their lexicological and etymological analysis. Starting with a brief description of the sources, it continues with a reconstruction of the semantic development of Hebrew/Aramaic loanwords and their derivatives on the background of typological parallels from other Jewish and non-Jewish languages.
Effects of ceramic particle size on cell attachment and viability in polyurethane-based bone adhesive composites
Authors: Erken Meryem , Tevlek Atakan , Hosseinian Pezhman , Topuz Bengisu , Aydin Halil Murat 
Published: November 2019

Millions of people require bone injury treatment and there have been many methods suggested for the stabilization of bone fractures. The need for the development of new methods is obvious since current stabilization methods are inadequate. Here, we described the development of polyurethane-based bone adhesives composites containing β-tricalcium phosphate ceramics in different sizes and ratios. To characterize the proposed materials, Fourier transform infrared spectroscopy, hydrogen-nuclear magnetic resonance, differential scanning calorimetry analyses together with scanning electron microscopy observations, and micro-computerized tomography imaging were examined. Furthermore, in vitro performance of the produced materials was tested by using MG63 human osteosarcoma cell line, and an ex vivo modeling study was conducted to test the mechanical performance of resulting materials using bovine rib bone. All materials were exhibited high porosity (above 90%) and homogeneous distribution of ceramic particles. Polyurethane scaffolds containing 40% (w/w) 1–2 mm β-tricalcium phosphate were shown the highest compressive strength as 1.34 ± 0.10 MPa. In addition, 85.75% cell viability was recorded according to the cytotoxicity analysis and also the cell proliferation was found highest in the same group. Taken into account the obtained results, the prepared polyurethane-based bone adhesive materials containing ceramics has a great potential to transform into a final product and meet a clinically significant medical need.
Urinary stone composition analysis of 3684 patients in the eastern Shandong region of China
Authors: Zhang Xuebao , Ma Jiajia , Wang Ning , Lin Chunhua 
Published: November 2019

Objective There has not been a study that analyzed the composition of urinary stones from patients in the eastern Shandong region of China. Thus, we explored the composition of urinary stones in the eastern Shandong region of China and discuss the clinical significance of the findings. Methods A total of 3684 urinary calculi from the eastern Shandong region were collected in our study. Compositions of the stones were analyzed using an Automatic Infrared Spectrum Analysis System (type LIIR-20). The results were verified through manual analysis of the spectrograms, which was accompanied by polarizing microscopy and chemical analysis if necessary. Results Among the 3684 specimens, there were 1767 single-component stones and 1917 mixed-component stones. According to the main components of the stones, the stones were divided into the following types: calcium oxalate monohydrate stones (1779, 48.3%), anhydrous uric acid stones (1105, 30.0%), carbonate apatite stones (590, 16.0%), ammonium magnesium phosphate hexahydrate stones (143, 3.9%), calcium oxalate dihydrate stones (36, 1.0%), and cystine stones (31, 0.8%). Conclusions There was a relatively high rate of uric acid stones in patients from the eastern Shandong region of China.
Prevalence of common causes of neuropathic pain in Korea: population-based observational study
Authors: Bang Seunguk , Kim Yee Suk , Lee Soyeon , Park Uijin , Kim Tae-kwan , Choi Yuna 
Published: November 2019

Objective To investigate the prevalence of complex regional pain syndrome (CRPS), post-herpetic neuralgia (PHN), trigeminal neuralgia (TN), and diabetic neuropathy (DN), common causes of neuropathic pain encountered in pain clinics. Methods We investigated the period prevalence rate of CRPS, PHN, TN, and DN using data from a Korean national electronic database from 2009 to 2013. Results The prevalence of CRPS decreased slightly throughout the study period, while the prevalence of PHN increased from 2009 to 2013. The prevalence of TN was reduced over the same period. The prevalence of DN increased from 2009 to 2012 but decreased in 2013. All four neuropathic diseases were more prevalent in individuals aged over 70 years. The prevalence of CRPS, PHN, and TN were more common in women than in men, but DN showed no gender difference. Conclusion While the prevalence of CRPS and TN has decreased in Korea, that of PHN and DN has increased. With the exception of DN, the neuropathic diseases were more prevalent in women. Further studies are necessary to investigate the risk factors and socioeconomic burden for each disease, and national efforts are essential to limit the development of these preventable neuropathic diseases.
Pediatric Stroke Impairs Theory of Mind Performance
Authors: Lo Warren , Li Xiangrui , Hoskinson Kristen , McNally Kelly , Chung Melissa , Lee JoEllen , Wang Ji , Lu Zhong-Lin , Yeates Keith 
Published: November 2019

Aim: This pilot study explored whether childhood stroke impairs performance on theory of mind (ToM) tasks and whether ToM task performance correlates with resting state connectivity in brain regions linked with social cognition. Method: We performed a case-control study of 10 children with stroke and 10 age- and gender-matched controls. They completed 2 ToM tasks, and resting state connectivity was measured with functional magnetic resonance imaging (MRI). Results: Children with stroke performed worse than controls on conative ToM tasks. Resting state connectivity in the central executive network was significantly higher and connectivity between right and left inferior parietal lobules was significantly decreased in children with stroke. Resting state activity and ToM performance were not significantly correlated. Interpretation: Childhood stroke results in poorer performance on specific ToM tasks. Stroke is associated with changes in resting state connectivity in networks linked with social cognition including ToM. Although the basis for these changes in connectivity is not well understood, these results may provide preliminary insights into potential mechanisms affecting social cognition after stroke. The findings suggest that further study of the effect of childhood stroke on network connectivity may yield insights as to how stroke affects cognitive functions in children.
Serum Biomarkers for Risk Assessment of Intrahospital Transports in Mechanically Ventilated Neurosurgical Intensive Care Unit Patients
Authors: Bender Michael , Stein Marco , Kim Seong Woong , Uhl Eberhard , Schöller Karsten 
Published: November 2019

Objective: Intrahospital transports (IHTs) of neurosurgical intensive care unit (NICU) patients can be hazardous. Increasing intracranial pressure (ICP) and/or decreasing cerebral perfusion pressure (CPP) as well as cardiopulmonary alterations are common complications of an IHTs, which can lead to secondary brain injury. This study was performed to assess several serum biomarkers concerning their potential to improve safety of IHTs in mechanically ventilated NICU patients. Methods: All IHTs of mechanically ventilated and sedated NICU patients from 03/2017 to 01/2018 were retrospectively analyzed. Intracranial pressure and CPP measurements were performed in all patients. Serum hemoglobin, hematocrit, and serum sodium were defined as serum biomarkers. Demographic data, computed tomography scan on admission, Simplified Acute Physiology Score and Acute Physiology and Chronic Health Evaluation II, modified Rankin Scale, indication and consequence of IHTs were analyzed. Alteration of ICP/CPP, hemodynamic and pulmonary events were defined as complications. The study population was stratified into patients with the occurrence of a complication and absence of a complication. Results: We analyzed a total number of 184 IHTs in 70 NICU patients with an overall complication rate of 57.6%. Of all, 32.1% IHTs had no direct therapeutic consequence. In patients with higher hemoglobin values prior to IHT less complications occurred, concerning ICP ( P = .001), CPP ( P = .001), hemodynamic ( P = .005), and pulmonary ( P < .0001) events. In addition, complications concerning ICP ( P = .001), CPP ( P = .001), hemodynamic ( P = .005), and pulmonary problems ( P = .002) were significantly lower in patients with higher hematocrit values before IHT. Conclusion: Intrahospital transports of mechanically ventilated NICU patients carry a high risk of increased ICP and hemodynamic complications and should be performed restrictively. Higher values of hemoglobin and hematocrit prior to IHT were associated with less complications with regard to ICP, CPP as well as hemodynamic and pulmonary events and could be helpful to assess the potential risk of complications prior to IHTs.
The nature and extent of prisoners’ social care needs: Do older prisoners require a different service response?
Authors: Tucker Sue , Hargreaves Claire , Cattermull Mark , Roberts Amy , Walker Tammi , Shaw Jennifer , Challis David 
Published: November 2019

Summary In light of longstanding concern about the lack of social care in prisons, the 2014 Care Act made local authorities in England responsible for identifying, assessing and meeting prisoners’ social care needs. However, service planning is difficult, for little is known about the level of demand or the extent to which the needs of older and younger prisoners differ. Against this background, face-to-face interviews (including screens for social care needs, substance misuse and mental health problems) were undertaken with a sample of male prisoners in North-West England. Findings Three hundred and ninety-nine participants were aged 18–49 and 80 aged 50 plus. Overall, more than a 10th of participants had problems maintaining personal hygiene, dressing and/or getting around the prison safely; a significant minority lacked meaningful occupation; and approaching a sixth acknowledged problems forming/maintaining relationships. Older prisoners were significantly more likely than younger prisoners to need help with personal hygiene, dressing and moving around safely and to identify problems with their physical health and memory. Applications The findings highlight the substantial number of older prisoners who could potentially benefit from some form of social care and support if they are to maintain their safety and dignity and make best use of their time in prison. They also underline the need to develop suitable screening and assessment tools for older prisoners, and for further research on the best service models for prisoners requiring intimate personal care.
Professional identity formation: The experience of regulated pharmacy technicians in Ontario
Authors: Gregory Paul , Austin Zubin 
Published: November 2019

Background: Despite being regulated and spoken about as professionals, there is little formal research examining professional identity formation among regulated pharmacy technicians. Methods: A semistructured interview protocol was generated, based on Holden et al.’s typology of professional identity formation (PIF). Regulated pharmacy technicians in Ontario with a minimum of 2 years’ experience working a minimum of 32 hours/week were recruited to participate. Interviews were transcribed, coded and analyzed based on professional identity formation. Results: A total of 15 regulated pharmacy technicians from southern Ontario participated in this study. Regardless of demographic background, most participants demonstrated identity splinting as the dominant form of professional identity formation. Issues related to social valuing of the role of the technician and environmental opportunities to develop and grow were highlighted as significant barriers. Interpretation: These findings suggest regulated pharmacy technicians have incomplete professional identities due in part to reasons linked to pharmacists and the pharmacy profession. The type of professional identity expressed by participants in this study may limit opportunities for full and optimal expression of their role. Conclusions: Further work is necessary to better understand the professional identity formation of regulated pharmacy technicians, to help support the evolution of this role. Can Pharm J (Ott) 2020;153:xx-xx.