bluuebunny/crossref_metadata_2025_split huggingface dataset:
The nonlinear deflection response of CNT/nanoclay reinforced polymer hybrid composite plate under different loading conditions
Authors: Lal Achchhe , Kanu Nand Jee 
Published: June 2020

Abstract
The carbon nanotubes (CNTs) are used as significant reinforcement materials in the advanced composites due to their improved mechanical properties. The carbon nanotubes reinforced nanocomposites have improved mechanical strength, and stiffness properties in addition to their reduced weight. Only a few percentages of CNTs (2–5% by weight) could be added to these nanocomposites as more volume fraction will deteriorate their mechanical properties. A computational approach is used in the present investigation to find the mechanical properties of the hybrid nanocomposite which is modeled by adding nanoclay particles into the conventional CNTs reinforced epoxy system. Using Halpin-Tsai approach (which is based on the micromechanical modeling) the mechanical properties of hybrid nanocomposites are evaluated. The effect of the CNTs and the nanoclay particles on the nonlinear transverse central deflection response of nanocomposite plate under different loading conditions is studied in detail. The simulation results of present investigation have been validated with the data sets of the deflection responses available in the references.
Optical and Gas sensing properties of BaxSr1-xTiO3 (with x=0.5 and x=0.7) thin films grown using Pulse Laser Deposition
Authors: Shastri Nipa M. , Raval Adhish V. , Joshi V.G. 
Published: June 2020

Abstract
Thin films of Barium Strontium Titanate (BST) have been fabricated using Pulse Laser Deposition (PLD) technique. Two stoichiometries of BaxSr1-xTiO3 with x=0.5 and x=0.7 are deposited on well cleaned quarts substrates in high vacuum chamber with oxygen pressure of 0.13mbar at 700˚C. XRD pattern shows perovskite structure of the films. Energy Dispersive X-ray (EDX) is used to determine the element concentration of both the films. Transmittance spectra of UV characterization shows decrement in transparency of the film as Barium (Ba) concentration increase and sharp cut-offs are observed at the band edge. Refractive Index (n), absorption coefficient (α), extinction coefficient (k), optical conductivity (σ) and optical band gap (Eg) are derived from UV-Vis spectroscopy. The calculated parameters for Ba0.5Sr0.5TiO3 and Ba0.7Sr0.3TiO3 are presented in this work. The present work also includes study of BST thin films as gas sensors.
Study on Effect of Abrasive Water Jet Machining Process Parameter on Taper Angle during Machining of Epoxy Resin Glass Fibre
Authors: Gawade Meghna K , Jatti Vijaykumar S , Phule Vaibhav V , Sawant Pranita V 
Published: June 2020

Abstract
Abrasive Water Jet Machining (AWJM) is one of the most advanced machining processes, which has the ability to machine various materials. In this paper, experiment was performed on cutting of epoxy fibre glass by AWJM. Epoxy fibre glass is a composite which consists of fibre glass cloth and epoxy resin as binder, achieved under specific heat and pressure. There are various process parameters such as water pressure, standoff distance, abrasive flow rate, traverse rate, abrasive etc. The water pressure and standoff distance was varied while performing the experiment and rest all parameters were kept constant. From this experiment taper angle was measured and it was observed that taper angle increases as the standoff distance increases, this is because the shape of the jet diverges with larger standoff distance. Minimum taper angle was observed as 0.34° at 32 ksi pressure, having 2 mm standoff distance. It was also observed that width of cut has significant effect on taper angle. From further calculations, the deviation of the cut slot for top width was observed as +1% to 5% and for bottom width it was -1% to 2%.
Blast resistance of steel plate shear walls designed for seismic loading
Authors: Sunagar Prashant , Bhashyam Aravind , Dharek Manish S , Sreekeshava K S , Ramegowda R S , Lakshmi H S 
Published: June 2020

Abstract
Since a blast loading or explosion can create nonlinear wave action and impact pressure on a structure, it necessary to construct a structure to resist blast loading as like other loads. In this study the nonlinear behaviour of a blast loading is simulated by calculating the pressure diagram with respect to time under the guidance of IS 4991 – 1968, code for “Criteria for Blast Resistant Design of Structures for Explosions above Ground”. The study carried out for different charge weight (100kg TNT, 200kg TNT and 400kg TNT) and standoff distances of 20metre. Nonlinear behaviour of a Blast loading to steel structures with shear plates of thickness 6 mm, 8 mm and 10 mm are modelled in ETABS and the analysis is carried out to obtain base shear, story displacement, story deformation pattern, column forces, etc.
Spatial variation of climate change issues using remote sensing technique
Authors: Rao Kumar R , Sreekeshava K S , Dharek Manish S , Sunagar Prashant C , Ganesh C R 
Published: June 2020

Abstract
The assessment of climate change can be carried out by analysing rainfall variability, temporal climatic changes, spatial interpolation of climatic factors and climatic risking. The climatic changes have consequences on precipitation pattern changes, temperature variation, and crop growing season alteration, increase of sea ice and grounded ice sheets. This has implications on ecosystem, human health, settlement and agriculture. Some of the repercussions attributed to temperature and precipitation increase is an increase of Cyclonic activities with increase of cyclonic wind speeds, Increase in Extreme Precipitation events like floods and droughts, agricultural yield is projected to decrease and negative impact on subsistence agriculture. The Tropical Cyclones intensifying in eastern Indian Ocean and crossing the coasts of Indian subcontinent year after year is a major cause of concern. The Latent Heat Release (LHR) of cyclones of Bay of Bengal carried out using advanced sensors like SSM/I (Special Sensor Microwave/Imager) on-board DMSP satellites (Defence Meteorological Satellite Program of US) for assessing spatial distribution of precipitation since LHR is responsible for maintenance and intensification of tropical cyclones and LHR can also enable measurement of brightness temperatures of atmospheric/ocean surfaces. The images of the clouds in visible and infrared region provide information about cloud aerial extent, type, and growth/decay. The raining clouds have high visible band reflectance and are tall due to upward motion indicating deep convection. These issues pertaining to climate changes through Remote sensing techniques is discussed in the paper.
In vitro evaluation of antimicrobial activity of chlorhexidine hexametaphosphate nanoparticle coatings on orthodontic elastomeric chains
Authors: Subramani Karthikeyan , Seo Han Na , Dougherty Joseph , Chaudhry Kishore , Bollu Prashanti , Rosenthal Kenneth S , Zhang Jian Feng 
Published: June 2020

Abstract
This study was conducted to evaluate antimicrobial activity of orthodontic elastomeric chains (OECs) coated with chlorhexidine (CHX) hexametaphosphate (HMP) nanoparticles and its effect on force decay. OECs were coated with CHX-HMP-5 (5 mM CHX and HMP), CHX-HMP-1 (1 mM CHX and HMP) nanoparticle colloidal solutions, CHX-5 (5 mM CHX) and CHX-1 (1 mM CHX) solutions. Release of CHX from coated OECs was evaluated over 28 days. Antimicrobial activity of the eluate collected on day 1 was tested against Streptococcus mutans and Lactobacillus rhamnosus by measuring the zone of inhibition after 4 days. OECs were observed by scanning electron microscope (SEM) to observe surface characteristics comparing: (1) uncoated and coated OECs and (2) before and after release of CHX. Force decay of OECs were measured over 28 days. SEM analysis showed that OECs were coated with nanoparticles. OECs coated with CHX-HMP-5 and CHX-HMP-1 released CHX over 28 days. The eluate from the coated OECs produced zones of inhibition after day 4 towards S. mutans and L. rhamnosus. Both CHX-HMP nanoparticle coated OEC released CHX over a period of 28 days that was capable of inhibiting the growth of S. mutans and L. rhamnosus. For all groups, the largest mean loss of force occurred over the first 24 h, followed by a relative plateau. All groups maintained >50% of the initial mean force over entire experiment of 28 days. This study showed that OECs can be coated with CXH-HMP nanoparticles that continuously elute the antimicrobial for extended periods. The coatings did not alter the force decay of OECs. Use of such coating on OECs can provide antibacterial activity to aid in the reduction of biofilm buildup and prevention of white spot lesions. This approach offers promising clinical applications.
Characterization of oscillation amplitude of contact angle during AC electrowetting of water droplets
Authors: Wikramanayake Enakshi , Bahadur Vaibhav 
Published: June 2020

Abstract
Most studies on electrowetting (EW) involve the use of AC electric fields, which cause droplets to oscillate in response to the sinusoidal waveform. Oscillation-driven mixing in droplets is the basis for multiple microfluidic applications. Presently, we study the voltage and AC frequency-dependent oscillations of electrowetted water droplets on a smooth, hydrophobic surface. We introduce a new approach towards analyzing droplet oscillations, which involves characterization of the oscillation amplitude of the contact angle (CA). An experimentally validated, fundamentals-based model to predict voltage and frequency-dependent CA oscillations is developed, which is analogous to the Lippmann’s equation for predicting voltage-dependent CAs. It is seen that this approach can help estimate the threshold voltage more accurately, than from experimental measurements of CA change. Additionally, we use a coplanar electrode configuration with high voltage and ground electrodes arranged on the substrate. This configuration eliminates measurement artefacts in the classical EW configuration associated with a wire electrode protruding into the droplet. An interesting consequence of this configuration is that the system capacitance is reduced substantially, compared to the classical configuration. The coplanar electrode configuration shows a reduced rate of CA change with voltage, thereby increasing the voltage range over which the CA can be modulated.
Hölder stability in determining elastic coefficients of Biot's system in poroelastic media
Authors: Zhang Wensheng , Jiang Zifan 
Published: June 2020

Abstract
In this paper, we investigate an inverse problem of determining the four spatially varying elastic coefficients of Biot’s system simultaneously, i.e., the two Lamé parameters, the dilatational coupling factor and the bulk modulus, by a single measurement of data on a neighbourhood of the boundary. Following the idea of the B-K method, we prove the Hölder stability estimate of this inverse problem based on Carleman estimates.
DeepAntigen: a novel method for neoantigen prioritization via 3D genome and deep sparse learning
Authors: Shi Yi , Guo Zehua , Su Xianbin , Meng Luming , Zhang Mingxuan , Sun Jing , Wu Chao , Zheng Minhua , Shang Xueyin , Zou Xin , Cheng Wangqiu , Yu Yaoliang , Cai Yujia , Zhang Chaoyi , Cai Weidong , Da Lin-Tai , He Guang , Han Ze-Guang 
Published: June 2020

Abstract

Motivation
The mutations of cancers can encode the seeds of their own destruction, in the form of T-cell recognizable immunogenic peptides, also known as neoantigens. It is computationally challenging, however, to accurately prioritize the potential neoantigen candidates according to their ability of activating the T-cell immunoresponse, especially when the somatic mutations are abundant. Although a few neoantigen prioritization methods have been proposed to address this issue, advanced machine learning model that is specifically designed to tackle this problem is still lacking. Moreover, none of the existing methods considers the original DNA loci of the neoantigens in the perspective of 3D genome which may provide key information for inferring neoantigens’ immunogenicity.

Results
In this study, we discovered that DNA loci of the immunopositive and immunonegative MHC-I neoantigens have distinct spatial distribution patterns across the genome. We therefore used the 3D genome information along with an ensemble pMHC-I coding strategy, and developed a group feature selection-based deep sparse neural network model (DNN-GFS) that is optimized for neoantigen prioritization. DNN-GFS demonstrated increased neoantigen prioritization power comparing to existing sequence-based approaches. We also developed a webserver named deepAntigen (http://yishi.sjtu.edu.cn/deepAntigen) that implements the DNN-GFS as well as other machine learning methods. We believe that this work provides a new perspective toward more accurate neoantigen prediction which eventually contribute to personalized cancer immunotherapy.

Availability and implementation
Data and implementation are available on webserver: http://yishi.sjtu.edu.cn/deepAntigen.

Supplementary information
Supplementary data are available at Bioinformatics online.
In search of lost mixing time: adaptive Markov chain Monte Carlo schemes for Bayesian variable selection with very largep
Authors: Griffin J E , Łatuszyński K G , Steel M F J 
Published: June 2020

SummaryThe availability of datasets with large numbers of variables is rapidly increasing. The effective application of Bayesian variable selection methods for regression with these datasets has proved difficult since available Markov chain Monte Carlo methods do not perform well in typical problem sizes of interest. We propose new adaptive Markov chain Monte Carlo algorithms to address this shortcoming. The adaptive design of these algorithms exploits the observation that in large-$p$, small-$n$ settings, the majority of the $p$ variables will be approximately uncorrelated a posteriori. The algorithms adaptively build suitable nonlocal proposals that result in moves with squared jumping distance significantly larger than standard methods. Their performance is studied empirically in high-dimensional problems and speed-ups of up to four orders of magnitude are observed.
“Treat them as a human being”: dignity in police detention and its implications for ‘good’ police custody
Authors: Skinns Layla , Sorsby Angela , Rice Lindsey 
Published: June 2020

AbstractHere, we examine the factors influencing whether those detained by the police feel treated with dignity. We develop a human rights-oriented conception of dignity rooted in the equal worth of human beings, encapsulated in detainees’ desire to be ‘treated like a human being’. The predictors of this are examined using multilevel modelling of survey data collected from 371 detainees in 27 custody facilities in 13 police forces in England and Wales in an Economic and Social Research Council-funded study of ‘good’ police custody. We found that perceptions of the material conditions predicted feelings of dignity, as did detainees’ reactions to being detained, their perceptions of the culture of police custody and the mechanisms used to hold the police to account. Feelings of dignity were also less likely for younger adults and for Black Asian and Minority Ethnic detainees, with these experiences being mediated by less trust in accountability mechanisms. This paper concludes by examining the implications for ‘good’ police custody.
The synstigma turns the fig into a large flower
Authors: Teixeira Simone P , Costa Marina F B , Basso-Alves João Paulo , Kjellberg Finn , Pereira Rodrigo A S 
Published: June 2020

AbstractThe synstigma is a structure formed by clusters of two to several stigmas, whether in the same or between different flowers. Although rare in angiosperms, synstigmas are found in c. 500 out of the c. 750 Ficus spp. (Moraceae). This floral structure is associated with fig-fig wasp pollinating mutualism. The synstigma structure and pollen tube pathways were studied in six Ficus spp. from Ficus section Americanae to test the hypothesis that the synstigma allows pollen grains deposited on a stigma to emit pollen tubes that can grow laterally and fertilize surrounding flowers. Syconia containing recently pollinated stigmas were collected and dissected, and the stigmas were processed for analyses with light and scanning and transmission electron microscopy. The arrangement of the synstigmas across species can be spaced or congested, with the number of stigmas per synstigma ranging from two to 20. Contact between the stigmas in a synstigma occurs by the intertwining of the stigmatic branches and papillae; their union is firm or loose. The pollen tube grows through live cells of the transmitting tissue until reaching the ovule micropyle. Curved pollen tubes growing from one stigma to another were observed in five out of the six species studied. The curvilinear morphology of pollen tubes probably results from competition by pollen between the stigmas composing a synstigma via chemotropic signals. The synstigma appears to be a key adaptation that ensures seed production by flowers not exploited by the fig wasps in actively pollinated Ficus spp.
A clinical-radiological framework of the right temporal variant of frontotemporal dementia
Authors: Ulugut Erkoyun Hulya , Groot Colin , Heilbron Ronja , Nelissen Anne , van Rossum Jonathan , Jutten Roos , Koene Ted , van der Flier Wiesje M , Wattjes Mike P , Scheltens Philip , Ossenkoppele Rik , Barkhof Frederik , Pijnenburg Yolande 
Published: June 2020

Abstract
The concept of the right temporal variant of frontotemporal dementia (rtvFTD) is still equivocal. The syndrome accompanying predominant right anterior temporal atrophy has previously been described as memory loss, prosopagnosia, getting lost and behavioural changes. Accurate detection is challenging, as the clinical syndrome might be confused with either behavioural variant FTD (bvFTD) or Alzheimer’s disease. Furthermore, based on neuroimaging features, the syndrome has been considered a right-sided variant of semantic variant primary progressive aphasia (svPPA). Therefore, we aimed to demarcate the clinical and neuropsychological characteristics of rtvFTD versus svPPA, bvFTD and Alzheimer’s disease. Moreover, we aimed to compare its neuroimaging profile against svPPA, which is associated with predominant left anterior temporal atrophy. Of 619 subjects with a clinical diagnosis of frontotemporal dementia or primary progressive aphasia, we included 70 subjects with a negative amyloid status in whom predominant right temporal lobar atrophy was identified based on blinded visual assessment of their initial brain MRI scans. Clinical symptoms were assessed retrospectively and compared with age- and sex-matched patients with svPPA (n = 70), bvFTD (n = 70) and Alzheimer’s disease (n = 70). Prosopagnosia, episodic memory impairment and behavioural changes such as disinhibition, apathy, compulsiveness and loss of empathy were the most common initial symptoms, whereas during the disease course, patients developed language problems such as word-finding difficulties and anomia. Distinctive symptoms of rtvFTD compared to the other groups included depression, somatic complaints, and motor/mental slowness. Aside from right temporal atrophy, the imaging pattern showed volume loss of the right ventral frontal area and the left temporal lobe, which represented a close mirror image of svPPA. Atrophy of the bilateral temporal poles and the fusiform gyrus were associated with prosopagnosia in rtvFTD. Our results highlight that rtvFTD has a unique clinical presentation. Since current diagnostic criteria do not cover specific symptoms of the rtvFTD, we propose a diagnostic tree to be used to define diagnostic criteria and call for an international validation.
Neuronal Network Topology Indicates Distinct Recovery Processes after Stroke
Authors: Latifi Shahrzad , Mitchell Simon , Habibey Rouhollah , Hosseini Fouzhan , Donzis Elissa , Estrada-Sánchez Ana María , Nejad H Rezaei , Levine Michael , Golshani Peyman , Carmichael S Thomas 
Published: June 2020

Abstract
Despite substantial recent progress in network neuroscience, the impact of stroke on the distinct features of reorganizing neuronal networks during recovery has not been defined. Using a functional connections-based approach through 2-photon in vivo calcium imaging at the level of single neurons, we demonstrate for the first time the functional connectivity maps during motion and nonmotion states, connection length distribution in functional connectome maps and a pattern of high clustering in motor and premotor cortical networks that is disturbed in stroke and reconstitutes partially in recovery. Stroke disrupts the network topology of connected inhibitory and excitatory neurons with distinct patterns in these 2 cell types and in different cortical areas. These data indicate that premotor cortex displays a distinguished neuron-specific recovery profile after stroke.
Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
Authors: Jamal Alainna J , Mozafarihashjin Mohammad , Coomes Eric , Powis Jeff , Li Angel X , Paterson Aimee , Anceva-Sami Sofia , Barati Shiva , Crowl Gloria , Faheem Amna , Farooqi Lubna , Khan Saman , Prost Karren , Poutanen Susan , Taylor Maureen , Yip Lily , Zhong Xi Zoe , McGeer Allison J , Mubareka Samira ,   Toronto Invasive Bacterial Diseases Network COVID-19 Investigators, Coleman Brenda L , Chen Danny , Farshait Nataly , Gold Wayne , Kandel Christopher E , Katz Kevin , Kozak Robert , Mazzulli Tony , Muller Matthew , Opavsky Anne , Ostrowski Mario , Plevneshi Agron , Rau Neil , Ricciuto Daniel , Richardson David , Rose David , Sales Valerie , Walmsley Sharon 
Published: June 2020

Abstract
We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness.
Model-based Cost-effectiveness of State-level Latent Tuberculosis Interventions in California, Florida, New York, and Texas
Authors: Jo Youngji , Shrestha Sourya , Gomes Isabella , Marks Suzanne , Hill Andrew , Asay Garrett , Dowdy David 
Published: June 2020

Abstract

Background
Targeted testing and treatment (TTT) for latent tuberculosis (TB) infection (LTBI) is a recommended strategy to accelerate TB reductions and further TB elimination in the United States. Evidence on cost-effectiveness of TTT for key populations can help advance this goal.

Methods
We used a model of TB transmission to estimate the numbers of individuals who could be tested by interferon-γ release assay and treated for LTBI with 3 months of self-administered rifapentine and isoniazid (3HP) under various TTT scenarios. Specifically, we considered rapidly scaling up TTT among people who are non–US-born, diabetic, living with human immunodeficiency virus (HIV), homeless or incarcerated in California, Florida, New York, and Texas—states where more than half of US TB cases occur. We projected costs (from the healthcare system perspective, in 2018 dollars), 30-year reductions in TB incidence, and incremental cost-effectiveness (cost per quality-adjusted life-year [QALY] gained) for TTT in each modeled population.

Results
The projected cost-effectiveness of TTT differed substantially by state and population, while the health impact (number of TB cases averted) was consistently greatest among non–US-born individuals. TTT was most cost-effective among persons with HIV (from $2828/QALY gained in Florida to $11 265/QALY gained in New York) and least cost-effective among people with diabetes (from $223 041/QALY gained in California to $817 753/QALY in New York).

Conclusions
The modeled cost-effectiveness of TTT for LTBI varies across states but was consistently greatest among people with HIV; moderate among people who are non–US-born, incarcerated, or homeless; and least cost-effective among people with diabetes.