bluuebunny/crossref_metadata_2025_split huggingface dataset:
Addition of Pachira aquatica oil and Platonia insignis almond in cookies: Physicochemical and sensorial aspects
Authors: Silva Tania G. , Kasemodel Marcia G. C. , Ferreira Otávio M. , da Silva Rogério C. L. , Souza Clitor J. F. , Sanjinez‐Argandona Eliana J. 
Published: May 2020

AbstractThis article investigated the use of Pachira aquatica (PA) fat and Platonia insignis (PI) nuts as ingredients in the preparation of cookies. Seven formulations containing PA fat and/or PI nuts were studied by changing the formulation proposed by AACC, and samples were evaluated considering physical–chemical, microbiological, and sensory characteristics. Formulations F1, F4, and F5 showed higher mass loss and lower expansion factor after cooking. Formulations F4, F6, and F7 presented a greater increase in diameter. In turn, formulations F5, F6, and F7 presented greater thickness. The content of fatty acids varied according to the composition of each biscuit, and formulations 2 and 3 presented the best lipid profile (oleic acid ~32%). In addition, it was observed that the addition of PI almond increased the fiber content (~7.15%). The sensory evaluation showed that formulation F5 obtained a score of 5, proving that the partial replacement of hydrogenated vegetable fat with PA fat and grated coconut with PI almond favored the panelists' purchasing decision. The results indicate that unconventional sources of lipids and nuts can be used without loss of quality in biscuits.
Nondestructive monitoring storage quality of apples at different temperatures by near‐infrared transmittance spectroscopy
Authors: Guo Zhiming , Wang Mingming , Shujat Ali , Wu Jingzhu , El‐Seedi Hesham R. , Shi Jiyong , Ouyang Qin , Chen Quansheng , Zou Xiaobo 
Published: May 2020

AbstractApple is the most widely planted fruit in the world and is popular in consumers because of its rich nutritional value. In this study, the portable near‐infrared (NIR) transmittance spectroscopy coupled with temperature compensation and chemometric algorithms was applied to detect the storage quality of apples. The postharvest quality of apples including soluble solids content (SSC), vitamin C (VC), titratable acid (TA), and firmness was evaluated, and the portable spectrometer was used to obtain near‐infrared transmittance spectra of apples in the wavelength range of 590–1,200 nm. Mixed temperature compensation method (MTC) was used to reduce the influence of temperature on the models and to improve the adaptability of the models. Then, variable selection methods, such as uninformative variable elimination (UVE), competitive adaptive reweighted sampling (CARS), and successive projections algorithm (SPA), were developed to improve the performance of the models by determining characteristic variables and reducing redundancy. Comparing the full spectral models with the models established on variables selected by different variable selection methods, the CARS combined with partial least squares (PLS) showed the best performance with prediction correlation coefficient (Rp) and residual predictive deviation (RPD) values of 0.9236, 2.604 for SSC; 0.8684, 2.002 for TA; 0.8922, 2.087 for VC; and 0.8207, 1.992 for firmness, respectively. Results showed that NIR transmittance spectroscopy was feasible to detect postharvest quality of apples during storage.
Biodiesel Production using Lewis Catalysts under Ultrasonic Activation
Authors: Kolet Mirit , Zerbib Daniel , Molina Karen , Nakonechny Faina , Nisnevitch Marina 
Published: May 2020

AbstractBiodiesel can be produced by transesterification of oil triglycerides, as well as by esterification of fatty acids using feedstock materials rich in free fatty acids)FFAs). Utilization of such feedstocks can gain substantial economical profit and solve a problem of disposal of residual raw materials. To find an effective method of biodiesel production from FFA, we developed esterification of FFAs under ultrasonic activation using Lewis acids as catalysts. Homologous catalyst BF3 and heterogeneous AlCl3 were highly effective in reactions of model FFAs methylation under ultrasonic activation, when the reaction yield reached 100 %. Ethylation at the same conditions was less successful.
Severe necrosis of the glans penis associated with calciphylaxis treated by partial penectomy
Authors: Tezuka Masato , Mizusawa Hiroya , Tsukada Manabu , Mimura Yuji , Shimizu Takaaki , Kobayashi Aya , Takahashi Yasufumi , Maejima Toshitaka 
Published: May 2020

IntroductionCalciphylaxis is characterized by marked vascular calcification and painful skin ulcers, and it has a poor prognosis.Case presentationThe patient was a 72‐year‐old male. He was referred for penile pain. He had a 4‐year history of dialysis therapy under a diagnosis of diabetic nephropathy. Black and yellow necrosis was observed involving the entire glans, accompanying severe pain. Computed tomography revealed marked calcification involving the thoracoabdominal aorta to iliac arteries, the dorsal artery of the penis and the corpus cavernosum, leading to a diagnosis of calciphylaxis. Penile pain gradually exacerbated and partial penectomy was performed. After surgery, penile pain promptly subsided. Pathological examination confirmed marked calcification of the microvascular wall and narrowing of the lumen.ConclusionWe reviewed 15 Japanese patients with calciphylaxis who had undergone penile surgery. Surgical treatment was considered to be effective at relieving penile pain, but the prognosis remained poor.
Current status and perspectives regarding the association between allergic disorders and cancer
Authors: Fereidouni Mohammad , Ferns Gordon A. , Bahrami Afsane 
Published: May 2020

AbstractWhile activation of immune system may lead to a lower risk of some diseases, it has been shown that a history of atopic allergic disorders such as asthma, hay fever, eczema, and food allergies could be related to several types of cancer. However, the evidence is not entirely conclusive. Two proposals suggest a possible mechanism for the association between allergic disorders and cancers: immune surveillance and the antigenic stimulation. The association of allergy and cancer may vary by cancer site and the type of exposure. The aim of current review was to summarize the current knowledge of the association between allergic diseases and the risk of cancers with particular emphasis on case–controls and cohort studies to estimate the cancer risk associated with allergy.
Multisite cell‐ and neural‐dynamics‐resolving deep brain imaging in freely moving mice with implanted reconnectable fiber bundles
Authors: Pochechuev Matvey S. , Solotenkov Maxim A. , Fedotov Ilya V. , Ivashkina Olga I. , Anokhin Konstantin V. , Zheltikov Aleksei M. 
Published: May 2020

AbstractWe demonstrate a reconnectable implantable ultraslim fiber‐optic microendoscope that integrates a branching fiber bundle (BFB) with gradient‐index fiber lenses, enabling a simultaneous fluorescence imaging of individual cells in distinctly separate brain regions, including brain structures as distant as the neocortex and hippocampus. We show that fluorescence images of individual calcium‐indicator‐expressing neurons in the brain of freely moving transgenic mice can be recorded, via the implanted BFB probe, in parallel with time‐ and cell‐resolved traces of calcium signaling, thus enabling correlated circuit‐dynamics studies at ‐multiple sites within the brain of freely moving animals.
Use of hemostatic agents for surgical bleeding in laparoscopic partial nephrectomy: Biomaterials perspective
Authors: Pacheco Margarida , Barros Alexandre A. , Aroso Ivo M. , Autorino Riccardo , Lima Estêvão , Silva Joana M. , Reis Rui L. 
Published: May 2020

AbstractIn recent years, there was an abrupt increase in the incidence of renal tumors, which prompt up the appearance of cutting‐edge technology, including minimally invasive and organ‐preserving approaches, such as laparoscopic partial nephrectomy (LPN). LPN is an innovative technique used to treat small renal masses that have been gaining popularity in the last few decades due to its promissory results. However, the bleeding control remains the main challenge since the majority of currently available hemostatic agents (HAs) used in other surgical specialities are inefficient in LPN. This hurried the search for effective HAs adapted for LPN surgical peculiarities, which resulted on the emergence of different types of topical HAs. The most promising are the natural origin HAs because of their inherent biodegradability, biocompatibility, and lowest toxicity. These properties turn them top interests' candidates as HAs in LPN. In this review, we present a deep overview on the progress achieved in the design of HAs based on natural origin polymers, highlighting their distinguishable characteristics and providing a clear understanding of their hemostat's role in LPN. This way it may be possible to establish a structure–composition properties relation, so that novel HAs for LPN can be designed to explore current unmet medical needs.
Semisolid vs Liquid Nutrients and 30‐Day Readmission in Gastrostomy Tube–Fed Patients: A Propensity‐Matched Analysis
Authors: Shinozaki Nana , Morita Kojiro , Matsui Hiroki , Jo Taisuke , Yasunaga Hideo 
Published: May 2020

AbstractBackgroundSemisolid nutrients have been widely used to prevent complications related to enteral nutrition (EN) in Japan. However, there are few data on the effect of feeding semisolid nutrient preparations. We compared 30‐day readmission rates of gastrostomy tube–fed patients who had been prescribed semisolid vs liquid nutrients on discharge.MethodsThis is a retrospective observational study using a Japanese nationwide inpatient database of data entered between June 2014 and March 2018. We identified patients aged ≥18 years who had received EN through gastrostomy during hospitalization. Patients were classified as having been prescribed semisolid vs liquid EN on discharge. After one‐to‐one propensity score matching, all‐cause 30‐day readmission rates were compared between the 2 groups.ResultsIn total, 5331 patients were identified, including a semisolid‐nutrients group (n = 2089) and a liquid‐nutrients group (n = 3242). Propensity score matching created 1912 pairs. The 30‐day readmission rates were 15.6% and 13.9% in the semisolid‐nutrients and liquid‐nutrients groups, respectively. No significant difference was observed between the groups (risk difference, 1.7%; 95% CI, −0.6 to 4.0%; P = .14).ConclusionAll‐cause 30‐day readmission of patients receiving gastrostomy tube feeding did not differ between those prescribed semisolid vs liquid nutrients on discharge. Randomized controlled trials are needed to accurately determine the effect of semisolid nutrients on clinical outcomes.
ASPEN Lipid Injectable Emulsion Safety Recommendations, Part 1: Background and Adult Considerations
Authors: Mirtallo Jay M. , Ayers Phil , Boullata Joseph , Gura Kathleen M. , Plogsted Steven , Anderson Collin R. , Worthington Patricia , Seres David S. , Nicolai Emily , Alsharhan Mohammad , Gutsul Liliia , Mason Angelina E. 
Published: May 2020

AbstractLipid injectable emulsions (ILEs) are complex pharmaceutical formulations used as a source of energy and essential fatty acids in parenteral nutrition. Issues associated with ILE use are distinctly different from oral fat and arise from emulsion stability, dose, and infusion tolerance. Since 1975, soybean oil has been the consistent source oil used in ILE formulations in the US. Partly because of safety concerns with the soybean‐based ILE and frequent and long‐standing problems with product inventory shortages, new ILE products have become available. Gaps in ILE best practices create a risk for ILE safety errors in prescribing, compounding, and administration of these products. This paper provides information on appropriate indications, dosing, and methods to avoid potential errors with ILE products in the US. This paper (Part 1) will focus on ILE background, information, and recommendations for adult patients, whereas Part 2 of this series will focus on neonatal and pediatric patient–specific information.
Dielectric barrier discharge plasma treatment affects stability, metal ion coordination, and enzyme activity of bacterial superoxide dismutases
Authors: Krewing Marco , Jung Christoph K. , Dobbelstein Elena , Schubert Britta , Jacob Timo , Bandow Julia E. 
Published: May 2020

AbstractA molecular‐level understanding of the effects of atmospheric‐pressure plasma on biological samples requires knowledge of the effects on proteins. Superoxide dismutases, which detoxify superoxide under oxidative stress conditions, play a key role in bacterial plasma resistance. Investigation of the impact of dielectric barrier discharge (DBD) treatment on purified superoxide dismutases SodA and SodB of Escherichia coli showed that DBD treatment caused a rapid protein degradation, with only 8% of protein remaining after 10 min. The affinity of SodA for the metal cofactor Mn2+ was reduced. Mass spectrometry, in conjunction with coupled‐cluster calculations, revealed that modifications of amino acid residues in the active site can explain the decreased metal affinity and a distortion of the coordination geometry responsible for the activity loss.
A conjugate BFGS method for accurate estimation of a posterior error covariance matrix in a linear inverse problem
Authors: Niwa Yosuke , Fujii Yosuke 
Published: May 2020

AbstractOne effective data assimilation/inversion method is the four‐dimensional variational method (4D‐Var). However, it is a non‐trivial task for a conventional 4D‐Var to estimate a posterior error covariance matrix. This study proposes a method to estimate a posterior error covariance matrix applied to the linear inverse problem of an atmospheric constituent. The method was constructed within a 4D‐Var framework using a quasi‐Newton method with the Broyden–Fletcher–Goldfarb–Shanno (BFGS) algorithm. The proposed method was constructed such that conjugacy among the set of increment vector pairs was ensured. It is theoretically demonstrated that, when this conjugate property is coupled with preconditioning, an analytical solution of a posterior error covariance matrix could be obtained from the same number of vector pairs as observations. Furthermore, to accelerate the speed of convergence, the method can be coupled with an ensemble approach. By performing a simple advection test, it was confirmed that the proposed method could obtain an analytical matrix of the posterior error covariance within the same number of iterations as the observations. Furthermore, the method was also evaluated using an atmospheric CO2 inverse problem, which demonstrated its practical utility. The evaluation revealed that the proposed method could provide accurate estimates not only of the diagonal but also of the off‐diagonal elements of the posterior error covariance matrix. Although far more expensive than optimal state estimation, the computational efficiency was found to be reasonable for practical use, especially in conjunction with an ensemble approach. The accurate estimation of a posterior error covariance matrix resulting from the proposed method could provide valuable quantitative information regarding the uncertainties of estimated variables as well as the observational impacts, which would be beneficial for designing observation networks. Furthermore, error correlations derived from the estimated off‐diagonal elements could benefit the interpretation of optimised parameter variations.
Variation in Reproductive Investment among Ohio Reservoir Largemouth Bass Populations
Authors: Pritt Jeremy J. , Zweifel Richard D. , Tyszko Stephen M. , Conroy Joseph D. 
Published: May 2020

AbstractReproductive investment, expressed in terms of fecundity and egg quality produced by individual female fish, varies among populations for many species, reflecting plasticity in life history strategies related to intraspecific density dependence or environmental variability. Fisheries scientists and managers have long sought to understand differences in Largemouth Bass Micropterus salmoides population dynamics, yet basic life history traits, such as variation in reproductive investment, remain largely unknown. We determined the fecundity–weight and ovary energy density–weight relationships (where fecundity indexes egg quantity and ovary energy density indexes egg quality) for Largemouth Bass populations from 19 Ohio reservoirs and examined factors that were correlated with population‐specific differences. We found that both relationships varied among reservoir populations, with some interannual variation in reservoirs sampled in multiple years. We then related fecundity and ovary energy density to (1) population characteristics, including population density (as indexed by standard shoreline boat electrofishing CPUE, fish/h) and growth (as indexed by the growth coefficient k from the von Bertalanffy growth function); and (2) reservoir characteristics, including reservoir size (as surface area) and productivity (as Secchi transparency depth). We found that populations with greater fecundity also exhibited greater ovary energy density, indicating that the quantity and quality of reproductive output were greater in some populations than in others. Populations with high reproductive investment were associated with low Largemouth Bass density, fast growth, large reservoir size, and high productivity (i.e., low Secchi transparency). The among‐population variation in reproductive investment provides evidence of density‐dependent control of fecundity and egg quality.
Outlook for the Future
Authors: Joshi C. , Caldwell A. , Muggli P. , Holmes S. D. , Shiltsev V. D. 
Published: May 2020

AbstractThe charge separation between electrons and ions that exists within an electron plasma density wave can create large electric fields. In 1979 Tajima and Dawson first recognized that the longitudinal component of the field of a so-called “relativistic” wave (one propagating with a phase velocity close toc), could be used to accelerate charged particles to high energies in a short distance [1]. The accelerating gradient of such a plasma wave,Eo, can be approximated—assuming a total separation of electrons and ions in such a wave with wavelengthλp = 2πc/ωp—as
Modeling radio-frequency energy-induced heating due to the presence of transcranial electric stimulation setup at 3T
Authors: Kozlov Mikhail , Horner Marc , Kainz Wolfgang , Weiskopf Nikolaus , Möller Harald E. 
Published: May 2020

Abstract
Purpose
The purpose of the present study was to develop a numerical workflow for simulating temperature increase in a high-resolution human head and torso model positioned in a whole-body magnetic resonance imaging (MRI) radio-frequency (RF) coil in the presence of a transcranial electric stimulation (tES) setup.

Methods
A customized human head and torso model was developed from medical image data. Power deposition and temperature rise (ΔT) were evaluated with the model positioned in a whole-body birdcage RF coil in the presence of a tES setup. Multiphysics modeling at 3T (123.2 MHz) on unstructured meshes was based on RF circuit, 3D electromagnetic, and thermal co-simulations. ΔT was obtained for (1) a set of electrical and thermal properties assigned to the scalp region, (2) a set of electrical properties of the gel used to ensure proper electrical contact between the tES electrodes and the scalp, (3) a set of electrical conductivity values of skin tissue, (4) four gel patch shapes, and (5) three electrode shapes.

Results
Significant dependence of power deposition and ΔT on the skin’s electrical properties and electrode and gel patch geometries was observed. Differences in maximum ΔT (> 100%) and its location were observed when comparing the results from a model using realistic human tissue properties and one with an external container made of acrylic material. The electrical and thermal properties of the phantom container material also significantly (> 250%) impacted the ΔT results.

Conclusion
Simulation results predicted that the electrode and gel geometries, skin electrical conductivity, and position of the temperature sensors have a significant impact on the estimated temperature rise. Therefore, these factors must be considered for reliable assessment of ΔT in subjects undergoing an MRI examination in the presence of a tES setup.
Right ventricular free wall longitudinal strain and strain rate quantification with cardiovascular magnetic resonance based tissue tracking
Authors: Qu Yang-Yang , Li Hao , Rottbauer Wolfgang , Ma Gen-Shan , Buckert Dominik , Rasche Volker 
Published: May 2020

AbstractCardiovascular magnetic resonance based tissue tracking (CMR-TT) was reported to provide detailed insight into left ventricular mechanical features. However, inadequate knowledge of the right ventricle (RV) mechanical deformation has been acquired by this advanced technique so far. It was the aim of this study to establish reference values of RV free wall (RVFW) global, regional and segmental longitudinal peak strain and strain rate (LS and LSR), and to investigate the gender- and age-related difference as well as the base-to-apex gradient of RVFW-LS and LSR with CMR-TT. 150 healthy volunteers (75 males/females) were retrospectively and continuously recruited and subdivided into three age groups (G20–40, G41–60 and G61–80). RVFW global, regional (basal, middle-cavity and apical) and segmental LS (GLS, RLS, SLS) along with systolic and diastolic LSR were generated by post-hoc CMR-TT analysis of standard steady-state free precession long-axis four-chamber view cine images acquired at 1.5T field strength. The reference value of myocardial RVFW-GLS was − 24.9 ± 5.2%. We found that females showed more negative GLS than males except in the youngest group, and no age-related difference of GLS was observed in both gender groups. RLS and SLS presented with the same age-related tendency as GLS. The basal and middle-cavity LS were similar between each other and significantly larger than apical LS. RVFW-GLSR resulted as − 1.73 ± 0.58 s−1 and 1.69 ± 0.65 s−1 during systolic and diastolic phases, respectively. The diastolic GLSR of males tended to decline with the ageing and was significantly lower than that of females in G61–80 group. Regional and segmental LSR showed significant gender-related differences in certain basal and apical region/segments without any age-related effects. CMR-TT overcomes the difficulty in measuring RV global and segmental deformation. The establishment of the vendor-, gender- and segment-specific reference values of RVFW-LS and LSR is essential for the rapid and efficient utilization of CMR-TT modality in the clinical routine.