bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nuclear Factor-Y (NF-Y), the Key Player in Plant Growth and Development: Prediction and Characterization of Vanilla planifolia
Authors: Arora Saavi , Ghai Devina , Sembi Jaspreet K. 
Published: November 2020

Background:
V. planifolia is of tremendous commercial importance as a source of an
important flavor, vanilla, which is the backbone of the culinary and perfumery industry. Hence, efforts
to ease cultivation and promote growth in this plant are the need of the hour. Nuclear factor-Y
(NF-Y) gene family, a class of vital transcription factors, plays a pivotal role in a large number of
developmental processes.

Objectives:
The present study aims to identify and characterize NF-Y gene family in Vanilla planifolia
which would bring insights to their role as key factors promoting growth and development in
this orchid.

Methods:
Physico-chemical characterization, protein structure prediction and interaction, the establishment
of evolutionary relationship and expression profiling were attempted using various in silico
tools.

Results:
Twenty five putative NF-Y members were identified in Vanilla planifolia, which were further
classified into three sub-classes, NF-YA (13), NF-YB (7) and NF-YC (5), on the basis of specific
domains and conserved regions. Prediction of three-dimensional structure was done on the basis
of structural similarity with NF-Y structure templates. Evolutionary analysis of the NF-Ys of
Arabidopsis thaliana and Oryza sativa classified these into three major clusters, which indicated
the similarity of functions. Variable expression of VpNF-Y genes confirmed their role in diverse
functions. VpNF-YA genes generally showed higher expression in vegetative tissues, while a few
VpNF-YBs showed seed-specific expression. Protein-protein interaction indicated complex formation
for optimum function.

Conclusions:
This work paves way for further functional characterization of NF-Y genes in Vanilla
planfolia.
The Recent Patents on Design and Investigation of Hydrostatic Spindle
Authors: Li Anling , He Qiang 
Published: November 2020

Background:
With the continuous improvement of spindle speed

Objective:
The purpose of this paper is to explore the problem of premature failure of hydraulic dynamic-
static bearing caused by temperature rise and vibration at high speed.

Methods:
The hydraulic dynamic-static spindles are taken as the research objects, and the spindles,
static pressure bearings, and oil system are carried out based on theoretical analysis design. MATLAB
is used to establish the mathematical model of hydraulic dynamic-static bearing, and thus the bearing
gap and the diameter of small holes are determined. ANSYS is used to carry out static and thermodynamic
simulation analysis of the main shaft and dynamic and static pressure bearings. In addition, the
temperature rise, rotation accuracy, and overall vibration, amplitude fluctuation and vibration power of
the spindle system are mainly tested, studied, and analyzed.

Results:
The highest temperature area of hydraulic dynamic-static bearings is mainly distributed around
the oil cavity inside the bearing and the bearing end surface; the speed of the spindle system continues
to increase, the rate of temperature rise accelerates, and the temperature stability range also rises. At the
same time, the vibration frequency is also increasing, and the operation is unstable during the acceleration
process. The rotation frequency of the spindle fluctuates greatly, but the vibration amplitude is
within the accuracy range.

Conclusion:
The obtained parameters will provide references for hydraulic dynamic-static spindle design
and reducing the design cycle.
Highly effective synthesis of dibromide of (+)-(1R, 2R)-and (-)-(1S, 2S) -1,2- diphenyl-1,2-ethylenediammonium (DPEN∙2HBr) assisted by microwave
Authors: Mitte Jeyson Andrés Cortés , Delgado Andrés Felipe Ojeda , Velásquez Luis Alberto Lenis 
Published: November 2020

Abstract::
In this work, the chiral salts (R,R)- and (S,S)-dibromide of 1,2-diphenyl-1,2-ethylenediammonium (R,R)-9 and
(S,S)-9 were synthesized, both by conventional and microwave heating, obtaining yields and optical rotations (c 0.43, H2O)
of 92%, +17.48° and 90%, -17.50°, respectively (conventional heating by 24 h) and 92%, +17.52° and 89%, -17.44°,
respectively (microwave heating by 1.4 h). These compounds were synthesized by means of the racemic intermediate (±)-
iso-amarine (±)-6, leading to the separation of their enantiomers, by fractional optical resolution and using as resolution
agents the enantiomers of (+)-(S)- and (-)-(R)-MA 3. The starting reagents were benzaldehyde and 28-30% NH4OH, which
are economical and commercially affordable. All synthesized compounds were characterized by melting point, solubility,
UV-vis, FT-IR (ATR). Imidazoline (±)-6 and salts (R,R)-9 and (S,S)-9 were additionally characterized by 1H and 13C NMR.
Polarimetry was determined to (R,R)-(+)-6, (S,S)-(-)-6, (S,R,R)-(+)-7, (R,S,S)-(-)-7, (S,S)-(+)-8, (R,R)-(-)-8, (R,R)-(+)-9
and (S,S)-(-)-9 compounds.
COVID-19 Pandemic: Current Scenario, Challenges and Future Perspectives
Authors: Zargar Ovais , Bashir Rohina , Zargar Mohammad Afzal , Hamid Rabia 
Published: November 2020

Background:
The new public health emergency of COVID-19 caused by a novel Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which originated in Wuhan, Hubei
province, China in December 2019, evolved into a pandemic in no time and is still in progression.
The novel virus mainly targets the lower respiratory system, leading to viral pneumonia, with other
associated complications of multi organ failure.

Discussion:
The bats, in particular Rhinolophus affinis, is a natural host of SARS-CoV-2 and the
virus is considered to have spread to humans through yet controversial intermediate host pangolins.
The incubation period ranges from 2-14 days and mode of person-to-person transmission is primarily
via the direct contact with the infected person or through the droplets generated by the infected
person during coughing or sneezing. The initiation of the infection process by SARS-CoV-2 virus
is the invasion of lung type II alveolar cells via a receptor protein called angiotensin-converting enzyme
2 (ACE2) present on the cell membrane with glycosylated spike (S) viral protein that mediates
host cell invasion. The main diagnostic tools employed are molecular methods based on nucleic
acid detection engaging real-time quantitative polymerase chain reaction (RT-qPCR) and a new
immunoassays based on antibodies IgM/IgG.

Conclusion:
Due to the lack of specific clinically approved anticovid-19 drugs or vaccines that
could be used for its prevention or treatment, the current management approach is essentially supportive
and symptomatic. The precautionary measures like, social distancing, cleaning hands with
soap or sanitizers, using disinfectant solutions to decontaminate the surfaces of things and proper
ventilation, wearing masks and other protective gears to curb transmission. The knowledge regarding
COVID-19 therapies is still evolving and collaborative efforts are being put in to discover
definitive therapies on different themes in the form of vaccines, repurposing drugs, RNA interference,
docking studies, etc.
Use of Virtual Reality to Assess Dynamic Posturography and Sensory Organization: Instrument Validation Study
Authors: Wittstein Matthew William , Crider Anthony , Mastrocola Samantha , Guerena Gonzalez Mariana 
Published: November 2020

Background
The Equitest system (Neurocom) is a computerized dynamic posturography device used by health care providers and clinical researchers to safely test an individual’s postural control. While the Equitest system has evaluative and rehabilitative value, it may be limited owing to its cost, lack of portability, and reliance on only sagittal plane movements. Virtual reality (VR) provides an opportunity to reduce these limitations by providing more mobile and cost-effective tools while also observing a wider array of postural characteristics.

Objective
This study aimed to test the plausibility of using VR as a feasible alternative to the Equitest system for conducting a sensory organization test.

Methods
A convenience sample of 20 college-aged healthy individuals participated in the study. Participants completed the sensory organization test using the Equitest system as well as using a VR environment while standing atop a force plate (Bertec Inc). The Equitest system measures the equilibrium index. During VR trials, the estimated equilibrium index, 95% ellipse area, path length, and anterior-posterior detrended fluctuation analysis scaling exponent alpha were calculated from center of pressure data. Pearson correlation coefficients were used to assess the relationship between the equilibrium index and center of pressure–derived balance measures. Intraclass correlations for absolute agreement and consistency were calculated to compare the equilibrium index and estimated equilibrium index.

Results
Intraclass correlations demonstrated moderate consistency and absolute agreement (0.5 < intraclass correlation coefficient < 0.75) between the equilibrium index and estimated equilibrium index from the Equitest and VR sensory organization test (SOT), respectively, in four of six tested conditions. Additionally, weak to moderate correlations between force plate measurements and the equilibrium index were noted in several of the conditions.

Conclusions
This research demonstrated the plausibility of using VR as an alternative method to conduct the SOT. Ongoing development and testing of virtual environments are necessary before employing the technology as a replacement to current clinical tests.
Cultura de seguridad de pacientes en profesionales de la salud en instituciones hospitalarias de Río Gallegos: Cultura de seguridad del adulto mayor
Authors: Perez Gabriela Bettina 
Published: November 2020

Dado el progresivo envejecimiento poblacional, los sistemas sanitarios deberán implementar políticas para una atención segura y de calidad. La propuesta de este trabajo es reflexionar y analizar la seguridad del paciente a través de los profesionales de la salud en dos Hospitales de la ciudad de Río Gallegos, Santa Cruz. Se presenta un diseño metodológico para la aplicación de un instrumento ya validado, versión traducida al español del cuestionario Hospital Surveyon Patient safety culture.
La Agricultura familiar en Santa Cruz, Patagonia Argentina: Caracterización de los núcleos agrícolas familiares
Authors: Birgi Jorge Alberto , Peri Pablo Luis , Ceconello Marcos Mauricio , Gargaglione Verónica Beatriz 
Published: November 2020

La agricultura familiar abarca a un grupo grande de personas que tienen distintos orígenes y una amplia diversidad cultural, pero que mantienen en común la producción de alimentos como forma de vida. El objetivo del presente trabajo fue caracterizar a la agricultura familiar de la provincia de Santa Cruz, determinando aspectos cualitativos, productivos y condiciones de producción de los núcleos de agricultura familiar. Se estudió el sector agrícola familiar de la provincia utilizando como base el análisis de 258 planillas del Registro Nacional de Agricultura Familiar relevadas durante los años 2014-2016. De dicho análisis surge que el tamaño medio de los predios en Santa Cruz es de 5 ha, se dedican principalmente a la agricultura y a la producción pecuaria, con predominio de la avicultura. En general, los productores realizan diversas actividades productivas en simultáneo. Se destaca por superficie implantada, la producción de forrajes, frutales, frutas finas y hortícolas de hoja. El presente trabajo es el primero en visibilizar numerosos aspectos de la agricultura familiar en Santa Cruz y presenta información inédita acerca de los núcleos de agricultura familiar en la provincia, contemplando a muchos productores que no figuran como tales en otros relevamientos como ser el Censo Agropecuario Nacional. Contar con este tipo de información resulta fundamental para las instituciones y los diversos actores sociales a fin de de monitorear su evolución en el tiempo y desarrollar políticas para su desarrollo y fortalecimiento.
Credit risk management and profitability: empirical evidence on Ethiopian commercial banks
Authors: Kidane Shibiru Tade 
Published: November 2020

The aim of the study was to assess the impact of credit risk management on the profitability commercial banks in Ethiopia. Secondary data was gathered from National Bank of Ethiopia for ten year periods (2010-2019). The study adopted Correlation analysis and fixed effect Model. Return on Asset was used to measure profitability of commercial banks, bank specific factors(Capital adequacy, Loan and Advances to total deposit, Non- Performing Loans, Bank size and Liquidity and macroeconomic factors (Inflation and Gross Domestic Product) as indicators of credit risk management. The findings showed that Credit Risk Management in terms of bank specific and macroeconomic factors has significant impact on profitability of commercial banks in Ethiopia. Also the result displayed that profitability of commercial banks is not affected by the amount of non- performing loans during the study. The study recommended that banks’ credit risk management should not give due devotion only to the internal factors but also to external factors exclusively (Gross Domestic Product and Inflation) in order to minimize their negative impact on profitability of commercial banks in Ethiopia
The Multiple Meanings of Jatio Sangsad Bhaban
Authors: Choudhury Bayezid Ismail , Armstrong Peter 
Published: November 2020

Jatio Sangsad Bhaban, the National Assembly Building of Bangladesh, is an iconic building and architectural landmark designed by American architect Louis I. Kahn. Jatio Sangsad Bhaban was constructed between 1962 and 1983 and is located in the heart of Dhaka, the nation’s capital. The extant literature on Louis I. Kahn’s work suggests that Jatio Sangsad Bhaban is a significant architectural masterpiece. One of its most notable features is its architectonic quality, providing it with the grandeur of a modern monumental building. In this context, this paper aims to examine the underlying multiple meanings, that is, socio-political, cultural, historic and philosophical meanings of the Jatio Sangsad Bhaban building By constructing and summarising meanings, rather than exploring the physical building itself, this paper supports the notion of multidimensional perspectives of monumental architecture. —The multiple meanings of icoic architecture through the lens of societal issues has been endorsed by many architectural critic. Accordingly, this paper considers the cultural, political, ethical and historical meanings of Jatio Sangsad Bhaban. Revealing and summarising other aspects apart from its architectonic dimensions is a new approach to understanding a widely acclaimed iconic building like Jatio Sangsad Bhaban
Factors Affecting Radiation Dose in Computed Tomography Angiograms for Pulmonary Embolism: A Retrospective Cohort Study
Authors: Nagpal Prashant , Priya Sarv , Eskandari Ali , Mullan Aidan , Aggarwal Tanya , Narayanasamy Sabarish , Parashar Kamesh , Bhat Ambarish P. , Sieren Jessica C. 
Published: November 2020

Objectives:
Computed tomography pulmonary angiogram (CTPA) is one of the most commonly ordered and frequently overused tests. The purpose of this study was to evaluate the mean radiation dose to patients getting CTPA and to identify factors that are associated with higher dose.

Material and Methods:
This institutionally approved retrospective study included all patients who had a CTPA to rule out acute pulmonary embolism between 2016 and 2018 in a tertiary care center. Patient data (age, sex, body mass index [BMI], and patient location), CT scanner type, image reconstruction methodology, and radiation dose parameters (dose-length product [DLP]) were recorded. Effective dose estimates were obtained by multiplying DLP by conversion coefficient (0.014 mSv•mGy−1•cm−1). Multivariate logistic regression analysis was performed to determine the factors affecting the radiation dose.

Results:
There were 2342 patients (1099 men and 1243 women) with a mean age of 58.1 years (range 0.2–104.4 years) and BMI of 31.3 kg/m2 (range 12–91.5 kg/m2). The mean effective radiation dose was 5.512 mSv (median – 4.27 mSv; range 0.1–43.0 mSv). Patient factors, including BMI >25 kg/m2, male sex, age >18 years, and intensive care unit (ICU) location, were associated with significantly higher dose (P < 0.05). CT scanning using third generation dual-source scanner with model-based iterative reconstruction (IR) had significantly lower dose (mean: 4.90 mSv) versus single-source (64-slice) scanner with filtered back projection (mean: 9.29 mSv, P < 0.001).

Conclusion:
Patients with high BMI and ICU referrals are associated with high CT radiation dose. They are most likely to benefit by scanning on newer generation scanner using advance model-based IR techniques.
Effect of coronavirus disease 2019 pandemic on case volume, spectrum, and perioperative coronavirus disease 2019 incidence in neurosurgical patients: An experience at a tertiary care center in India
Authors: Sharma Anil Kumar , Gandhoke Charandeep Singh , Nayak Nitish 
Published: November 2020

Background:The volume and spectrum of neurosurgical procedures being performed during the coronavirus disease 2019 (COVID-19) pandemic have significantly changed as compared to the pre-COVID-19 period. The objective of this study is to examine this change and draw useful conclusions.Methods:We collected data retrospectively of all patients who attended outpatient clinics and who were operated at our institute under the department of neurosurgery from October 23, 2019, to August 23, 2020. These data were then divided into two groups (pre-COVID period and during the COVID pandemic) and compared.Results:Out of the 388 surgeries performed, 284 surgeries were performed during the pre-COVID period, and 104 surgeries were performed during the COVID pandemic. During this ongoing COVID pandemic, the total number of surgeries performed by the department of neurosurgery decreased significantly by 63.38%, the proportion of routine surgeries performed decreased from 50.35% to 19.23% and the proportion of minor cases increased from 19.72% to 30.77%. The Outpatient Clinic Workflow decreased by 72.3% as compared to the pre-COVID period, and the perioperative COVID-19 reverse transcription-polymerase chain reaction positive incidence in our neurosurgical patients was 11.71%.Conclusion:This paper highlights the drastic reduction in the operative workflow and the outpatient clinic workflow during the ongoing corona pandemic which will have significant collateral damages in the long run. We will have to strike the right balance between providing our patients with the best medical treatment while limiting the spread of the COVID-19 infection.
Zastosowanie metodyk zarządzania projektami w górnictwie – cykl życia projektu górniczego
Authors: KACPERSKI Andrzej 
Published: November 2020

Zarządzanie projektami jest już obszerną i niezależną dziedziną nauki o zarządzaniu. Wiedza z tego zakresu jest rozpowszechniana nie tylko przez uczelnie wyższe, lecz również, a w zasadzie można by powiedzieć, że głównie przez stowarzyszenia zrzeszające praktyków i teoretyków zarządzania projektami takie jak IPMA czy Project Management Institute. Organizacje te prezentują różne podejścia do zarządzania projektami. Obecnie wiele firm zmaga się z dylematem, które podejście do zarządzania projektami stosować. Tradycyjne, dobrze znane przez większość praktyków zarządzania, czy zwinne, młodsze podejście. W referacie przedstawione zostało w jaki sposób popularne metodyki zarządzania projektami definiują projekt oraz jego cykl życia. Zostało to skonfrontowane z charakterystyką projektu górniczego co jednocześnie wskazuje, które z metodyk mają potencjał do zastosowania w górnictwie.
The implementation of traditional Balinese architecture in the theater of Badung Regency
Authors: Saputra Alan Darma , Herwindo Rahadhian Prajudi , Kusliansjah Yohanes Karyadi 
Published: November 2020

Bali Island is a famous tourist destination in the world and this has made it a gathering hub and multicultural meeting center for tourists from several countries, thereby, raising concern on the possibility of the area losing its traditional Balinese architecture. It is necessary to make adjustments by adopting the shape of the old Balinese building. This means the emergence of new functions is not a taboo but a new design challenge, therefore, the traditional Balinese architecture and theater provisions were combined to produce a neo-vernacular architecture by using descriptive qualitative method. This led to the application of Asta Kosala-kosali in the theater space, modification on the roof, body and legs shape of the Balinese building, and the integration of the construction system and materials in the Balinese theater architecture.
© 2020 Alan Darma Saputra, Rahadhian Prajudi Herwindo, Yohanes Karyadi Kusliansjah
A Prospective Observational Study of Hypomagnesemia in Critically Ill Paediatric Patients
Authors: Chandrashekhar Channanayaka , Pillai Reshmi , Vasudev Prajwala Hassan , Babu Tirin , Panachiyil George Mathew 
Published: November 2020

Introduction: Magnesium deficiency, a common finding in critically ill patients, is associated with increased need for respiratory support, increased duration of ICU stay and mortality. The primary objective of our study is to assess the prevalence of hypomagnesaemia in critically ill children (requiring inotropic support, respiratory support, and fluid resuscitation) on admission in the Paediatric Intensive Care Unit (PICU). The secondary objective is to evaluate its relationship with the length of hospital stay and mortality.
Methods: This prospective observational study was conducted in the PICU of a tertiary care hospital. In this study, serum magnesium levels at admission were measured along with other laboratory tests, after informed consent. Serum magnesium levels were assayed in our laboratory. The normal range of serum magnesium in our lab is 1.7-2.7 mg/dl. During admission in PICU, there was follow-up for ionotrope administration, need for mechanical ventilation, APACHE II score, PICU length of stay and mortality.
Results: In this study, 350 critically ill children requiring hemodynamic / respiratory support were chosen. However, 83 children were excluded from study as they were discharged against medical advice. The prevalence of hypomagnesemia in this study was 43.4%. There was no significant association between hypomagnesemia, duration of hospital stay and mortality.
Conclusion: Hypomagnesaemia is a common finding in critically ill paediatric patients, however there is no significant association noted in regards to length of hospital stay, duration of mechanical ventilation, inotropic support and mortality.