bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining the multiplicative relationships between teachers’ competence, value and pedagogical beliefs about technology integration
Authors: Cheng Sheng‐Lun , Chen Sheng‐Bo , Chang Jen‐Chia 
Published: November 2020

AbstractThe purpose of this study is to examine the relationship between competence beliefs, value beliefs, pedagogical beliefs and teachers’ technology integration. The sample includes two hundred and five in‐service teachers from 121 schools in Taiwan. Using the latent moderated structural equations approach, this study finds that there is a synergistic interaction between competence beliefs and traditional pedagogical beliefs. The negative effect of traditional pedagogical beliefs on technology integration is amplified when competence beliefs is at an extremely low level. On the contrary, the maladaptive nature of traditional pedagogical beliefs is neutralized when the level of competence beliefs increases. Value beliefs in terms of perceived interest and usefulness significantly predicted technology integration. However, when controlling for the effects of these beliefs, constructivist pedagogical beliefs and perceived cost are not significant predictors. These findings revealed that the additive effect model commonly seen in the literature is short of capturing the complexity of teacher beliefs about technology integration. Stakeholders are suggested to devote their resources to foster competence and value beliefs about technology integration instead of pedagogical beliefs.
Practitioner NotesWhat is already known about this topic:

Teacher beliefs demonstrate an additive relationship with technology integration.
Competence beliefs, value beliefs and pedagogical beliefs are significantly associated with teacher technology integration.
What this paper adds:

Teacher beliefs demonstrate a multiplicative relationship with technology integration.
Competence beliefs serve as a buffer between traditional pedagogical beliefs and technology integration.
Perceptions of cost and constructivist pedagogical beliefs are not significant predictors of teachers’ intention to integrate technology.
Implications for practice and policy:

Teachers’ beliefs about their capability, interest and the usefulness of integrating technology, not pedagogical beliefs, are suggested to be the reasonable targets for future intervention work.
Stakeholders may consider devoting their resources to first support teachers who have strong traditional pedagogical beliefs, low competence beliefs and low values beliefs about technology integration.
Implications of detecting serum monoclonal protein by MASS‐fix following stem cell transplantation in multiple myeloma
Authors: Abeykoon Jithma P. , Murray David L. , Murray Isaiah , Jevremovic Dragan , Otteson Gregory E. , Dispenzieri Angela , Arendt Bonnie K. , Dasari Surendra , Gertz Morie , Gonsalves Wilson I. , Kourelis Taxiarchis V. , Muchtar Eli , Dingli David , Warsame Rahma , Go Ronald S. , Lacy Martha Q. , Leung Nelson , Buadi Francis , Lin Yi , Kyle Robert A. , Rajkumar Vincent , Kumar Shaji , Kapoor Prashant 
Published: November 2020

SummaryMeasurable residual disease (MRD) assessment by marrow‐based next‐generation flow cytometry (NGF) following autologous stem cell transplantation (ASCT) may lead to false‐negative results due to patchy marrow involvement and extramedullary disease in patients with multiple myeloma. We assessed the value of simultaneous MRD evaluation with NGF and serum matrix‐assisted laser desorption ionization time‐of‐flight mass spectrometry (MASS‐FIX). Of all 61 complete responders who were NGF‐negative for MRD, around day‐100 post ASCT, 59% were MASS‐FIX‐positive. At median follow‐up of 26 months, 69% of MASS‐FIX(+)/NGF(−) patients were alive and progression‐free versus 96% of MASS‐FIX(‐)/NGF(−) patients, P = 0·02. MASS‐FIX, a simple peripheral blood‐based assay complements marrow‐based NGF to accurately prognosticate patients with myeloma.
Quality of life in children with tuberous sclerosis complex: A pediatric cohort study
Authors: Ding Yifeng , Wang Ji , Zhou Yuanfeng , Yu Lifei , Zhang Linmei , Zhou Shuizhen , Wang Yi 
Published: November 2020

AbstractAimsTo evaluate the quality‐of‐life (QOL) impairment and identify the possible risk factors in patients with tuberous sclerosis complex (TSC) in China.MethodsThe parent proxy‐report PedsQL 4.0 Generic Core Scales were administered to 124 caregivers of children with TSC (aged 2‐18 years). For comparison, the survey was also conducted in a demographically group‐matched sample of healthy controls (HCs) (aged 2‐18 years).ResultsA total of 124 children with TSC and 206 HCs were recruited. The mean parent proxy‐report total scale score, physical health summary score, and psychosocial health summary score for children with TSC were 65.0 (SD 19.7), 77.6 (SD 22.9), and 58.0 (SD 21.3), respectively, compared with the HC values of 83.6 (SD 14.3), 87.2 (SD 16.9), and 82.8 (SD 15.9). There were statistically significant differences between the two groups (P < .0001). TSC2 mutation (P = .033), epilepsy (P = .011), seizure before 2 years old (P = .001), course of epilepsy (more than 2 years) (P = .001), high reported seizure frequency (more than once a month) (HRSF) (P = .007), multiple antiepileptic drugs (≥2) (P = .002), intellectual disability (ID) (mild and moderate ID, P < .0001, and severe and profound ID, P < .0001), and TANDs (P < .0001) (ADHD, P = .004; agoraphobia, P = .007; and social anxiety disorder, P < .0001) were closely related to lower QOL scores.ConclusionThis study is the first large cohort study on QOL in children with TSC in China. The results of the PedsQL 4.0 indicated that the QOL of children with TSC is significantly lower than that of HCs. TSC2 mutation, epilepsy, early onset, long disease course and HRSF, ID, and TANDs are risk factors for poor QOL.
Dynamic planning method of economic operation optimization model
Authors: Jing Jing 
Published: November 2020

AbstractEnterprise dynamic planning is a branch of operations research and multi‐stage decision‐making processes. This method can be used to solve multi‐objective decision‐making problems, thereby optimizing the overall effect of the system. Aiming at the dynamic programming method of economic operation optimization model, this article studies a multi‐objective dynamic programming algorithm and improves the algorithm. Taking the optimization arrangement of enterprise production plan as an example, according to the production capacity, production cost and inventory cost of the enterprise, a dynamic planning method is adopted to establish a production plan arrangement model. The experimental results show that using the method proposed in this article to dynamically plan the economic operation optimization model can not only improve the convergence of the results but also improve its accuracy. This result solves the optimization problem of the enterprise's product production plan.
Post‐transplant lymphoproliferative disorder with cutaneous involvement: A series of four cases
Authors: Ferreira Maria Carolina Corsi , Arai Seque Camila , Enokihara Mílvia Maria Simões e Silva , Batista Mariana Dias , Tomimori Jane , Porro Adriana Maria 
Published: November 2020

AbstractBackgroundPost‐transplant lymphoproliferative disorders (PTLD) are lymphoid proliferations associated with post‐transplant immunosuppression. Most originate from B cells and are associated with Epstein‐Barr virus (EBV) infection. Although extranodal involvement is common, cutaneous presentation is rare.ObjectiveTo report and characterize cutaneous manifestations of PTLD from clinical, histopathologic, and immunohistochemistry standpoints.MethodsPatients' information was obtained retrospectively by reviewing medical records. Skin biopsies were submitted to histological and immunohistochemistry analysis, and EBV detection was performed by in situ hybridization and polymerase chain reaction (PCR) analysis. Staging examinations were included. A literature review of reported cutaneous PTLD cases was performed.ResultsWe describe two cases of primary cutaneous and 2 cases of systemic PTLD with secondary cutaneous manifestations. All had late onset disease, which presented at least 6 years after transplantation. Histopathologic findings were compatible with monomorphic PTLD in three cases and plasmacytic hyperplasia in one case. EBV was detected in two patients. Both patients with systemic disease had fatal outcome, and those with primary cutaneous involvement responded to treatment.LimitationsDue to the rare incidence of cutaneous manifestation of PTLD, the analysis of a large number of cases was not possible.ConclusionAlthough rare, PTLD should be considered in the differential diagnosis of late onset cutaneous complications post‐renal transplant.
Constraint‐induced movement therapy for children with neonatal brachial plexus palsy: a randomized crossover trial
Authors: Werner Julie M , Berggren Jamie , Loiselle Jennifer , Lee Gina Kim 
Published: November 2020

AimTo determine if constraint‐induced movement therapy (CIMT) is more effective than standard care in improving upper‐limb activity outcomes in children with neonatal brachial plexus palsy (NBPP).MethodTwenty‐one children with NBPP (mean age 25mo, SD=10.3, range=17–48mo; 11 males, 10 females) were enrolled in a crossover trial and randomly allocated to first receive CIMT or standard care, each for 8 weeks. The intervention arm consisted of 3 weeks of casting the unaffected limb followed by 5 weeks of transference activities. The Assisting Hand Assessment (AHA) was used to measure bimanual activity performance at baseline, 8 weeks, and 16 weeks, scored by blinded raters. The Pediatric Motor Activity Log‐Revised (PMAL‐R) was used as a caregiver‐reported secondary outcome measure.ResultsAfter concealed random allocation (n=21), there were no significant differences on demographics or baseline measures. CIMT was superior compared to control in terms of bimanual activity performance with a mean difference in AHA change score of 4.8 (SD=10.5, p=0.04, Cohen’s δ=0.46). There were no significant differences between treatment conditions on the PMAL‐R.InterpretationCIMT is favored over standard care for bimanual activity performance. Future research should investigate a longer follow‐up period, additional comparator interventions, and analyse differences by participant characteristics.What this paper adds

Gains in bimanual activity performance were greater after constraint‐induced movement therapy (CIMT) compared to no CIMT.
Frequency and quality of movement were not significantly different between treatment groups.
Factors contributing to energy loss in left ventricle during diastolic and systolic phases in elderly patients
Authors: Futami Shutaro , Ishikawa Joji , Maeda Teppei , Kawano Masuyo , Sakurayama Chieko , Harada Kazumasa 
Published: November 2020

AbstractBackgroundThe change of left ventricular function deteriorated with age because of gradual increases of blood pressure may result in increased energy loss (EL) in left ventricle (LV). The present study investigated EL in LV among hypertensive elderly patients and examined factors contributing to EL.MethodsA single‐center retrospective study was performed on elderly hypertensive outpatients (≥65 years) who underwent echocardiography (N = 105). EL in the LV was measured using a vector flow mapping system, and factors affecting peak EL during the early‐diastolic phase (ED‐EL), late‐diastolic phase (LD‐EL), and systolic phase (Sys‐EL) were evaluated.ResultMean age was 79.9 ± 6.4 years (male 43%). Mean ED‐EL, LD‐EL, and Sys‐EL were 42.1 ± 46.7, 75.6 ± 60.2, and 40.4 ± 40.2 mJ/N/s. In a stepwise regression analysis, the E/e’(lateral) (unstandardized B = 0.005, 95%CI −0.03 to 0.007, standardized β = 0.434, P < .001) was identified as factors affecting ED‐EL. The factors affecting LD‐EL were E/A ratio (B = −0.122, 95%CI −0.176 to −0.068, β = −0.470, P < .001) and time velocity integral (TVI) in LVOT (unstandardized B = 0.002, 95%CI 0.000 to 0.004, β = 0.247, P = .021). The factors influencing Sys‐EL were TVI in LVOT (B = 0.002, 95%CI 0.001 to 0.004, β = 0.390, P < .001), E/A ratio (B = −0.054, 95%CI −0.093 to −0.015, β = −0.258, P = .008), left ventricular outflow tract (LVOT) diameter (B = −0.006, 95%CI −0.010 to −0.002, β = −0.307, P = .006), and left ventricular mass index (B = 0.000, 95%CI 0.000 to 0.001, β = 0.208, P = .039).ConclusionPeak EL in the LV was higher during diastolic phase than systolic phase among elderly hypertensive patients. Peak EL both during late‐diastolic phase and systolic phase was affected by systolic blood flow in LVOT and LV transmitral flow pattern.
Pulmonary hypertension in connective tissue diseases, new evidence and challenges
Authors: Vonk Madelon C. , Vandecasteele Els , van Dijk Arie P. 
Published: November 2020

AbstractPulmonary arterial hypertension is a lethal complication of different connective tissue diseases such as systemic sclerosis, mixed connective tissue disease and systemic lupus erythematosus. Although the treatment possibilities for patients with pulmonary arterial hypertension have increased in the last two decades and survival of patients with idiopathic pulmonary arterial hypertension has improved, the latter is not the case for patients with pulmonary arterial hypertension associated with connective tissue disease. In this narrative review, we review recent literature and describe the improvement of early diagnostic possibilities, screening modalities and treatment options. We also point out the pitfalls in diagnosis in this patient category and describe the unmet needs and what the focus of future research should be.
The role of potassium in atherosclerosis
Authors: Sahranavard Toktam , Carbone Federico , Montecucco Fabrizio , Xu Suowen , Al‐Rasadi Khalid , Jamialahmadi Tannaz , Sahebkar Amirhossein 
Published: November 2020

AbstractBackgroundAtherosclerosis (AS) is a chronic progressive inflammatory condition with a leading prevalence worldwide. Endothelial dysfunction leads to low‐density lipoprotein trafficking into subendothelial space and the subsequent form of oxidized LDL (ox‐LDL) within intimal layer, perpetuating the vicious cycle of endothelial dysfunction. K+ exerts beneficial effects in vascular wall by reducing LDL oxidization, vascular smooth muscle cells (VSMCs) proliferation, and free radical generation. K+ also modulates vascular tone through a regulatory effect on cell membrane potential.Materials and MethodsThe most relevant papers on the association between ‘potassium channels’ and ‘atherosclerosis’ were selected among those deposited on PubMed from 1990 to 2020.ResultsHere, we provide a short narrative review that elaborates on the role of K+ in atherosclerosis. This review also update the current knowledge about potential pharmacological agents targeting K+ channels with a special focus on pleiotropic activities of agents such as statins, sulfonylureas and dihydropyridines.ConclusionIn this review, the mechanism of different K+ channels on vascular endothelium will be summarized, mainly focusing on their pathophysiological role in atherosclerosis and potential therapeutic application
A cross‐sectional evaluation of knowledge among Chinese dentists regarding the treatment of traumatic injuries in primary teeth
Authors: Wu Tian‐tian , Li Jin‐yi , Yang Ke‐yu , Wang Pan‐xi , Yuan Jia‐xue , Guo Qing‐yu , Liu Fei 
Published: November 2020

AbstractBackground/AimInjuries to the primary dentition affect children's esthetics, function, and mental health. They may also affect the development of the permanent teeth. The knowledge of dentists about deciduous tooth trauma is rarely evaluated. The aim of this study was to evaluate the knowledge and attitude of dentists in China regarding traumatic dental injuries to primary teeth.Material and MethodsA self‐administered online questionnaire containing questions on demographic data and knowledge based on a clinical scenario was given to a purposive sample of dentists, recruited by a non‐probability convenience sampling method. The chi‐square test was used for statistical analysis, with the significance level set at P <.05.ResultsA total of 394 out of 409 dentists provided valid data. There was no significant difference in demographic data. Questions about the treatment of hard dental tissue injuries in primary teeth presented a correct‐response rate of 66.4%, with the highest correct‐response rate for enamel fracture (n = 368, 93.4%) and lowest for complicated crown‐root fracture with pulp exposure (n = 104, 26.4%). Questions about treatment of luxation injuries in primary teeth presented a correct‐response rate of 66.6%, with subluxation presenting the highest correct‐response rate (n = 391, 99.2%). Factors associated with higher correct‐response rates were specialist disciplines, educational qualifications, workplaces, experience of injured teeth treated, and educational experience about primary tooth trauma. No significant differences were found in the correct‐response rates of dentists with different years of work experience. Lack of cooperation from children was considered a major obstacle for treatment. Special lectures and Internet courses were the most preferred methods of obtaining knowledge.ConclusionThe results suggest that it is necessary to enhance dental trauma education for dentists in China. More attention needs to be paid to trauma in primary dentition to ensure adequate treatment for traumatized primary teeth.
Mouthguard use and attitudes regarding dental trauma among elite cross‐country mountain biking and field hockey athletes
Authors: Tinoco Justine Monteiro Monnerat , Sassone Luciana Moura , Stevens Roy Harris , Martins Daniel Deluiz , Grangeiro Neto Joao Alves , Tinoco Eduardo Muniz Barretto 
Published: November 2020

AbstractBackground/AimsCross‐country mountain biking and field hockey are two Olympic sports that pose a potential risk for dentofacial trauma. However, mouthguard use is not mandatory in either of these sports and knowledge about tooth rescue among athletes is often neglected. The aim of this cross‐sectional epidemiological survey was to evaluate the prevalence of sports‐related dentofacial injuries, mouthguard use, and attitudes regarding tooth rescue among cross‐country mountain biking and field hockey athletes participating at pre‐Olympic competitions held in Rio de Janeiro, Brazil.Materials and MethodsA convenience sample of 217 athletes from 33 countries participating in cross‐country mountain biking (n = 82; mean age = 30.96 ± 8.52 years) and field hockey (n = 135; mean age = 19.72 ± 2.46 years) pre‐Olympic competitions were examined clinically, and they answered a questionnaire regarding previous history of sports‐related dentofacial injuries, attitudes toward mouthguard use, and tooth rescue.ResultsThere were 120 (55.30%) males and 97 (44.70%) females who participated in the study. The prevalence of facial trauma was higher in mountain biking (54.88%) than in field hockey (26.66%, P < .001). Fracture was the most prevalent facial injury in mountain biking (80%), while laceration was the most prevalent in field hockey (30.55%). Extensive dental injuries occurred more often in mountain biking (47.37%) than in hockey (12.50%). The teeth most often affected were the maxillary central incisors in both mountain biking (57.89%) and field hockey (93.75%). Mouthguard use was more frequent among field hockey athletes (41.48%) than in mountain biking (1.22%, P < .001). The overall knowledge about tooth rescue was low, and most of the athletes in both sports did not know what to do in case of an avulsed tooth.ConclusionsPrevalence of dentofacial injuries among XCO‐MTB and field hockey athletes participating at this pre‐Olympic event was high. The majority of the athletes in this study did not use mouthguards and were unaware of recommendations in the case of an avulsed tooth.
Hands‐on training based on quantifying radiant exposure improves how dental students cure composites: Skill retention at 2‐year follow‐up
Authors: Balhaddad Abdulrahman A. , Marghalani Abdullah A. , Raderman Michael A. , Miginsky Elaine , Massey Ward , Strassler Howard , Anne Melo Mary 
Published: November 2020

AbstractIntroductionThe durability and longevity of composite restoration are much dependent on the accurate delivery of the energy required to polymerise the material. This study aimed to investigate the extent to which undergraduate dental students acquire and retain light‐curing skills following hands‐on training.Materials and MethodsHands‐on training comprises faculty tutoring for critical aspects of the light‐curing procedure, such as distance and angulation of the light‐curing tip. Assessments of the students' ability to deliver a specified radiant exposure to class III and I simulated RBCs using a dental simulator (MARC‐PS®) at three different time points after the training. Data were analysed using repeated measure ANOVA.ResultsImmediately after the training, students' performance on curing was improved (p < .05). Overall, the radiant exposure increased after training, but the students lost some of the benefits with time. For curing in the anterior section (anterior sensor‐class III), the mean radiant exposure values increased by approximately 20% after the training. After 2 years, the values were 15% greater than baseline values. For curing in the posterior section (posterior sensor‐class I), the mean radiant exposure values increased by approximately 150% after the training. A significant decrease (p < .05) was observed; however, the radiant exposure values were still 82% greater than the baseline after 2 years.ConclusionA hands‐on training dedicated to light‐curing procedures facilitated acquisition and retention up to a 2‐year follow‐up of skill on how light cure composite inside the mouth. The training was more relevant for curing in posterior areas, where orientation can significantly impact light‐curing. A hands‐on training where the radiant exposure can be measure gave objective measurement metrics to guide the curing performance. This approach is an effective means of teaching practical skills to dental students.