bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ferroptosis: regulated cell death
Authors: Čepelak Ivana , Dodig Slavica , Dodig Daniela Čepelak 
Published: July 2020

Abstract
Ferroptosis is a recently identified form of regulated cell death that differs from other known forms of cell death morphologically, biochemically, and genetically. The main properties of ferroptosis are free redox-active iron and consequent iron-dependent peroxidation of polyunsaturated fatty acids in cell membrane phospholipids, which results in the accumulation of lipid-based reactive oxygen species due to loss of glutathione peroxidase 4 activity. Ferroptosis has increasingly been associated with neurodegenerative diseases, carcinogenesis, stroke, intracerebral haemorrhage, traumatic brain injury, and ischemia-reperfusion injury. It has also shown a significant therapeutic potential in the treatment of cancer and other diseases. This review summarises current knowledge about and the mechanisms that regulate ferroptosis.
Performance Analysis of Static Precise Point Positioning Using Open-Source GAMP
Authors: Malik Jabir Shabbir 
Published: July 2020

Abstract
In addition to Global Positioning System (GPS) constellation, the number of Global Navigation Satellite System (GLONASS) satellites is increasing; it is now possible to evaluate and analyze the position accuracy with both the GPS and GLONASS constellation. In this article, statistical analysis of static precise point positioning (PPP) using GPS-only, GLONASS-only, and combined GPS/GLONASS modes is evaluated. Observational data of 10 whole days from 10 International GNSS Service (IGS) stations are used for analysis. Position accuracy in east, north, up components, and carrier phase/code residuals is analyzed. Multi-GNSS PPP open-source package is used for the PPP performance analysis. The analysis also provides the GNSS researchers the understanding of the observational data processing algorithm. Calculation statistics reveal that standard deviation (STD) of horizontal component is 3.83, 13.80, and 3.33 cm for GPS-only, GLONASS-only, and combined GPS/GLONASS PPP solutions, respectively. Combined GPS/GLONASS PPP achieves better positioning accuracy in horizontal and three-dimensional (3D) accuracy compared with GPS-only and GLONASS-only PPP solutions. The results of the calculation show that combined GPS/GLONASS PPP improves, on an average, horizontal accuracy by 12.11% and 60.33% and 3D positioning accuracy by 10.39% and 66.78% compared with GPS-only and GLONASS-only solutions, respectively. In addition, the results also demonstrate that GPS-only solutions show an improvement of 54.23% and 62.54% compared with GLONASS-only PPP mode in horizontal and 3D components, respectively. Moreover, residuals of GLONASS ionosphere-free code observations are larger than the GPS code residuals. However, phase residuals of GPS and GLONASS phase observations are of the same magnitude.
Effect of Different Pre-Treatments on Antinutrients and Antioxidants of Rice Bean (Vigna umbellata)
Authors: Kaur Damanpreet , Dhawan Kajal , Rasane Prasad , Singh Jyoti , Kaur Sawinder , Gurumayum Sushma , Singhal Somya , Mehta C. M. , Kumar Vikas 
Published: July 2020

Abstract
Rice bean (Vigna umbellata) is a legume that belongs to Vigna genus. Native to Indo-Chinese region, it is considered to be an ‘under-utilized’ or ‘orphan’ crop. Rice bean is known to possess high nutritional potential and antioxidant activity. But the use of rice bean supplementation in routine diet is limited despite its high nutritional profile due to the presence of non-nutritional factors. Thus, various pre-treatments like soaking, germination, oven roasting, sand roasting, boiling and pressure cooking at different time and temperature were carried out to reduce the anti-nutritional content of rice bean and to study its effect on antioxidant activity and phytochemical content. All the pre-treatments were able to significantly reduce the anti-nutrient content in rice bean, but germination showed the maximum reduction. Also germinated rice bean showed the maximum antioxidant potential and maximum content of total phenols, total flavonoids, vitamin C and carotenoids. Rice bean has been underutilized so far, owing to its antinutrient content and low popularity. This experiment attempted to use low cost processing to reduce the content of antinutrients and track the antioxidant content in rice bean. The concluded processing could be adopted for commercial applications for dietary supplementation.
The origin and course of severe thunderstorm outbreaks in Poland on 10 and 11 August, 2017
Authors: Sulik Sławomir , Kejna Marek 
Published: July 2020

Abstract
This study documents the evolution of severe thunderstorm outbreaks that occurred on 10 and 11 August, 2017 in Poland. This study used cloud-to-ground lightning-strike data from the PERUN lightning detection network managed by the Polish Institute of Meteorology and Water Management – National Research Institute. In the description of storm phenomena the authors also applied synoptic maps, meteorological radar data, vertical atmosphere soundings and meteorological data from the station in Poland. The aim of this study was to trace the causes of the upward movement of supercells including the Mesoscale Convective System day by day, and to examine relationships between lighting distributions on 10 and 11 August, 2017. In Poland, on August 10, 2017, 154,524 cloud-to-ground flashes (CG) occurred, and 56,510 CG flashes the next day. On August 10, around 18% of all flashes had a positive current, but 29% the next day. The spatial distribution of the lightning in Poland was computed for 10×10-km grid cells. Based on the map analysis it was found that on those two days most of the positive flashes occurred in Greater Poland and Kuyavian-Pomeranian voivodeships, as well as on the border of Opolskie and Lower Silesia.
Identifying High Nature Value farmlands on a national scale based on multivariate typology at municipality (LAU 2) level
Authors: Mądry Wiesław , Olik Marcin , Roszkowska-Mądra Barbara , Studnicki Marcin , Gozdowski Dariusz , Wójcik-Gront Elżbieta 
Published: July 2020

Summary
High Nature Value farmlands in Europe are of greatest importance in the conservation of biodiversity. Their environmental importance has been recognized for some time, and has been studied mostly in Western Europe. This article describes the results of multivariate statistical analyses performed on data (13 variables) collected from the latest National Agricultural Census and the CORINE database to provide a typology of farmlands with respect to their nature value at municipality level (LAU 2, Local Administrative Units level 2) across Poland. All municipalities were grouped into eight categories (types). Some of the farmland categories were considered to be High Nature Value farmland (HNVf). The following interrelated variables mostly contributed to the identification of HNVf: share of protected areas and forest, grassland, arable land and fallow, farmland cover diversity, and rate of nitrogen fertilization. HNVf was identified in 958 out of 2173 municipalities, covering 44% of the territory of Poland. The identified HNVf also overlaps partially (61%) with LFAs (Less Favored Areas). Farmlands with the highest nature value are located mostly across mountain and hilly areas, close to forests, and protected areas on lowlands and river valleys. The identified HNV farmlands are characterized by low-input farming systems and a large share of semi-natural habitats with a high landscape mosaic.
Flow rate effect on partially modified potato starch microspheres formation process
Authors: Muneer Roaa Mohammed , Hadi Nizar Jawad , Al-Zubiedy Ali 
Published: July 2020

Abstract
Natural biopolymers are the most likely choice for biomedical applications, and starches can be considered the best materials for such applications. This comes from the fact of their natural origin and their high biodegradable behavior. Native starches have weak hydrogen bonding and a leaching behavior – making it a candidate for drug delivery application. Still, to make starch useful as a drug delivery carrier, this hydrogen bonding must be strengthened. In this work, native sweet potato starch was used, and the hydrogen bonding between starch molecules was enhanced by introducing glycerol as a hydrogen bonding source and sodium alginate (SA) as a thickener. This blend was tested by means of FTIR and DSC, and based on the test results, improved hydrogen bonding had taken place. Furthermore, potato starch microspheres were successfully produced at different flow rates. In the work, a microfluidic capillary device was harnessed to form microsphere generating total flow rates ranging between (0.00031 and 0.00054) cm3/sec. Herein, a starch/sodium alginate/glycerol mixture was used as a dispersed phase and PVA+tween 80 was used as continuous phase. At high flow rates (0.00062-0.00054) cm3/sec, the microspheres took an oval shape. At flow rates (0.00034-0.00048) cm3/sec, the microspheres took a spherical shape. At very low flow rate (0.00031) cm3/sec, the microspheres shell was weak and caused core oozing. In this work, starch microspheres were successfully formed with diameter ranging from (151-263) µm.
The Liverpool Care Pathway for the dying patient: Euthanasia through the back door, or the sign of poor death education?
Authors: Jones Allan R. 
Published: July 2020

Abstract
The Liverpool Care Pathway for the Dying Patient (LCP) was an integrated care pathway for patients in the final days or hours of life, developed at the Royal Liverpool University Hospital in conjunction with the Marie Curie Palliative Care Institute, Liverpool. The LCP became increasingly the normative style of care for patients in the terminal stage across NHS England from the 1990s onwards. Following significant questions raised in Parliament, by the media and other stakeholders, an independent review panel was established under Baroness Neuberger in 2013 to investigate the LCP. The findings of the panel were published as More Care Less Pathway: a Review of the Liverpool Care Pathway identifying significant failings in the delivery of the LCP thus leading to it being phased out some six months later. Rather than being euthanasia through the backdoor, many of the criticisms of the LCP and its poor implementation are indicative of poor communication, limited knowledge of the dying process and a paucity of death education.
Recycling of Oil Fly Ash in the Adsorption of Dyes From Industrial Wastewater
Authors: Primerano Patrizia , Milazzo Maria Francesca 
Published: July 2020

Abstract
The use of oil fly ash after the recovery of heavy valuable metals was investigated. More specifically, its use, as an adsorbent of dyes from industrial wastewater, was evaluated. Methylene blue was used as a model compound to study the adsorption capacity of the proposed carbonaceous residue from metal recovery treatments. The effects of contact time, initial dye concentration, and absorbent dose were investigated. The maximum amount of dye was adsorbed after one hour. Moreover, 1-3 g of residues were necessary for the removal of 200-1000 mg dm–3 from 0.050 dm3 of contacted solution. The Langmuir isotherm model was in good agreement with the adsorption equilibrium data, indicating a maximum monolayer saturation capacity of approximately 40 mg/g at 25 °C. High abatement efficiencies (up to 99 %) were obtained, and the adsorbed dye was released almost immediately by re-contacting with water. The adsorption capacity was at least four times lower than that of commercially available active carbon. The double treatment of oil fly ash with deionised water and hydrochloric acid allows for the extraction of over 85 % of the vanadium, iron, and nickel content in the ash. However, the negligible or zero cost of solid residues, otherwise disposed in landfills, indicates their potential as a valid alternative. The use of oil fly ash for both recovery of heavy valuable metals and the subsequent removal of dyes from wastewater suggest a zero-waste process.
The Influence of the Slope Exposure on the Soil Aggregation and Structure, Water Stability of Aggregates, and Ecological Microstructure Formation of the Ravine Forest Soils in Pre-Dnipro Region (Ukraine)
Authors: Bozhko Kateryna , Bilova Natalia 
Published: July 2020

Abstract
The soil aggregation and structure, water stability of aggregates, and peculiarities of microstructure formation of the ravine forest soils in Dnipropetrovsk region on the example of the northern variant of the ravine forest “Kapitanivskiy” have been identified. The soil properties of southern and northern ravine exposures have been compared. The soil structure, aggregate composition, water stability of aggregates as well as soil-forming processes of the ravine ecosystem have been analyzed. Micro-morphological studies have shown a high degree of aggregation of the upper (0–60 cm) horizons of the soil profile. The structure-forming process is of a zoogenic origin. Aggregates of coprolite nature contain well-disintegrated plant remains. Dark gray, almost black color along the entire area of the micromorphological slide is due to a large amount of organic compounds, which indicates active processes of humification. Fine-dispersed humus consists of a large number of evenly spaced humus clusters. The type of humus is mull. The skeleton consists of minerals of various sizes, dominated by quartz and feldspars. Plasma is humus-clay, homogeneous throughout the entire slide, anisotropic with speckled glowing. Microstructure is mainly aggregated and, in some places, spongy, depending on a microzone of the soil slide. Elemental microstructure is of plasma-silty type. The area of the visible surface of the pores in the upper horizons of the soil profile is fairly large (40%). Pores are round and elongated, of regular shape, here and there with remains of small invertebrates. The deeper the soil slide is, the smaller the area of visible pores along with aggregation becomes. Correlating with micromorphological characteristics, water resistance of structural aggregates reaches very high (90.01% ± 3.07) values in the upper horizons of the soil slide, decreasing at depths. The coefficient of pedality is rather high (7.83 ± 0.81) in the upper horizons, decreasing at depths.
Local community participation in wildlife conservation and management in Rungwa Game Reserve, Tanzania
Authors: Tarimo Kileti V. , Olotu Moses I. 
Published: July 2020

Abstract
Local community participation in wildlife conservation and management is known to have existed for many years. However, the socio-economic activities regarding community participation remain questionable. Incorporating the views of the local community in the process of decision-making and providing alternative livelihood solutions are important steps towards sustainable conservation. The main aim of this study was to investigate the effects of community participation in sustainable wildlife management in Rungwa Game Reserve. A survey was conducted of the households in Rungwa and Mwamagembe villages with a sample size of 98 respondents. The study used a cross-sectional research design. Data were collected from different respondents at a single point in time. The main research methods used for data collection included: questionnaire surveys, key informant interviews, field observations, focus group discussions and a review of documents. Descriptive data were summarised and presented in frequency tables and charts. Content analysis was also used to determine relationships between the variables measured. The findings revealed both positive and negative effects of wildlife conservation and management. The results revealed that local communities provided confidential information pertaining to illegal activities. The findings further indicated that there was a failure of the game reserve authorities to allow meaningful local participation and equitable sharing of the benefits, which could be attributed to hatred, resentment, and illegal harvesting of natural resources from the game reserve, resulting in poor wildlife conservation. This study recommends the encouragement and a strengthening of the involvement of local communities in wildlife conservation for the sustainable utilisation of natural resources.
Nutrition Intake, Health Status, Education and Economic Growth: A Causality Investigation
Authors: Raji Rahman Olanrewaju 
Published: July 2020

Abstract
This paper examines the causal relationship between nutrition intake, health status, education and economic growth within a six-variate VEC framework, forecast error variance decomposition and impulse response function techniques, covering the period from 1990 to 2013, using quarterly data in Nigeria. This paper includes control variables in order to eliminate variable omission bias, unlike most existing studies. The results suggest the presence of long-run, bicausal relationships between the candidate variables of the study. In addition, the short-run unidirectional causal relationships are found between main variables, including a causal relationship running from nutrition and fiscal policy to education, as well as a causal link running from education and economic growth to health status. These findings support the existing theories. The results based on the model and empirical data suggest that the government should allocate more resources to human development in order to enhance productivity and boost economic growth. Similarly, there is a need to design adequate mechanisms to ensure proper allocation of the limited resources and avoid their embezzlement by corrupt government officials.
Numerical Solution of SDRE Control Problem – Comparison of the Selected Methods
Authors: Hałas Krzysztof , Krysiak Eugeniusz , Hałas Tomasz , Stępień Sławomir 
Published: July 2020

Abstract
Methods for solving non-linear control systems are still being developed. For many industrial devices and systems, quick and accurate regulators are investigated and required. The most effective and promising for nonlinear systems control is a State-Dependent Riccati Equation method (SDRE). In SDRE, the problem consists of finding the suboptimal solution for a given objective function considering nonlinear constraints. For this purpose, SDRE methods need improvement.
In this paper, various numerical methods for solving the SDRE problem, i.e. algebraic Riccati equation, are discussed and tested. The time of computation and computational effort is presented and compared considering selected nonlinear control plants.
Isozyme polymorphism and seed and cone variability of Scots pine (Pinus sylvestris l.) in relation to local environments in Poland
Authors: Przybylski Paweł , Masternak Katarzyna , Jastrzębowski Szymon 
Published: July 2020

Abstract
Evolutionary processes lead to the survival of individuals best adapted to local environment. This gives rise to allele polymorphism and genetic diversity of populations. Isoenzyme proteins, which are the product of gene expression, are an effective tool for tracking these changes. On the other hand, the reproductive potential of a given population can be assessed based on its ability to produce viable and efficiently germinating seeds. The present results combine molecular analyses of isoenzyme proteins with anatomical and morphological studies of Scots pine seeds (Pinus sylvestris L.). The study was conducted in 6 populations that are characteristic of this species occurrence range in the country. The results confirm the correlation between seed weight and embryo size. They also show a population from northeastern Poland had a higher effective number of alleles and seed with lower germinative energy and capacity. There was genetic homogeneity in all except for the population from Woziwoda, which was significantly different based on the Fst test. The genetic characteristics of Scots pine from Woziwoda may be associated with the lower levels of rainfall that occur there during the growing season. The results improve our knowledge of Scots pine variability and contribute to the discussion of the impact of local environment on genetic variability.
Foodborne Pathogens on Meat Stored in Major Central Cold Rooms in Ibadan and their Susceptibility to Antimicrobial Agents
Authors: Adesokan H. K. , Funso-Adu K. , Okunlade O. A. 
Published: July 2020

Abstract
Foodborne pathogens are the leading cause of illness and death in developing countries and are often associated with poor hygiene and unsafe food storage conditions. Using central cold rooms with alternate power supply in preserving meats due to erratic power supply is common among meat traders in Nigeria. However, the public health safety of the operations of this practice remains un-investigated. We conducted a microbial assessment of aseptically collected meat swabs from three selected major cold rooms in Ibadan for Staphylococcus aureus, Listeria monocytogenes, Salmonella spp. and Escherichia coli using standard procedures. Antibiotic susceptibility was determined using 14 different antibiotics at standard concentrations following Kirby-Bauer Assays. The data were analysed with Stata 12.0 using bivariate and logistic regression analyses. Of 180 meat swabs collected, 42.2 % were positive for S. aureus, 22.2 % for L. monocytogenes, 20.0 % for Salmonella spp. and 6.7 % for E. coli. All of the isolates exhibited total resistance to seven of the antibiotics. Escherichia coli showed the highest resistance to 12 antibiotics, followed by Salmonella spp. (11 antibiotics), L. monocytogenes (10 antibiotics) and S. aureus (7 antibiotics). Sampling locations were significantly associated with the prevalence of L. monocytogenes (P = 0.008) and S. aureus (P = 0.000), but not with Salmonella spp. (P = 0.435) or E. coli (P = 0.117). The study revealed a heavy microbial contamination with major foodborne pathogens characterized by a high level of antibiotic resistance. These findings portend that the current operations associated with the practice of using central cold rooms in meat preservation in Nigeria undermine public health safety and need to be urgently addressed.
Evaluation of the effectiveness of high-speed rail projects in the Czech Republic in terms integration potential
Authors: Viturka Milan , Pařil Vilém 
Published: July 2020

Abstract
The paper deals with the evaluation of the effectiveness of the construction of high-speed rails/HSR in the Czech Republic with an emphasis on the perception of their potential impact on labour market integration. The introductory part analyses the position of the main Central European metropolises in the HSR network as a tool for transnational integration, where the leading position of German and Swiss metropolises was confirmed. The main goal of the paper is assessing the impact of HSR construction projects on the work attractiveness of Czech metropolitan regions using the model of marginal rate of labour mobility model determined by the ratio of income and cost increases (including variant scenarios of lost time costs as negative externality). Its application combines economic and geographic analysis and thus contributes to the integration of space and time into economic theory. The performed analyses demonstrate the most significant positive impacts of the construction of HSR on the work attractiveness of Prague, followed by Brno. Regarding the adequate effects of the operating speed, it is possible to evaluate them as secondary due to the small distances of the affected residential centres. Overall, we expect that the implementation of the discussed projects will not have a significant impact on the labour mobility of the population and it is therefore necessary to pay attention to their other benefits.