bluuebunny/crossref_metadata_2025_split huggingface dataset:
Liderazgo transformacional y desarrollo sostenible ambiental verde en docentes de la Universidad Nacional Herminio Valdizán
Authors: Santacruz Espinoza Atanacia , Montenegro Muguerza Humberto , Pizarro Alejandro Armando , Estacio Flores Hamilton 
Published: November 2020

El concepto desarrollo sostenible verde articula las diversas disciplinas científicas del saber actuar, pensar, vivir, sentir. Por ende, el líder transformador debe propiciar el cambio de una economía negra a una economía ambiental verde. Por ende, garantizar los derechos naturales a través del empoderamiento sostenible en el tiempo. La investigación fue aplicada, nivel explicativo, y diseño descriptivo-correlacional, con un muestreo probabilístico y estratificado. Por su alcance es descriptiva y por su finalidad cuantitativa, cualitativa y mixto. Metodológicamente, la investigación pone en diálogo fuentes bibliográficas diversas. Se ha realizado el análisis de los resultados utilizando los estadígrafos inferencial y descriptiva. El método utilizado es el método científico y como métodos específicos: hermenéutico, dogmático y heurístico.Se utilizó la técnica de encuesta y el instrumento cuestionario de encuesta. Como principal conclusión se tiene que existe una correlación directa fuerte (rho =0,788) y altamente significativo con (p-valor: 0,000) entre el liderazgo transformacional y el desarrollo sostenible verde Los estudiantes, docentes y administrativos de la Universidad nacional Hermilio Valdizán tuvieron un nivel medio o regular, se ha descubierto en ellos que dan orientación a la sociedad para el reciclado adecuado, propicia conversatorios para no pagar elevados precios por el consumo de electricidad, comprar solo lo que se necesita, dejar de comprar alimentos chatarra en pro de la salud, utilizar el transporte de la universidad o público en vez de privado; ello, para la sostenibilidad generacional con práctica de una economía circular a través del uso de tecnología responsable.
Antibiotic induced biofilm formation of novel multidrug resistant Acinetobacter baumannii ST2121 clone
Authors: Çimen Müberra , Düzgün Azer Özad 
Published: November 2020

AbstractThe aim of this study was to identify antimicrobial resistance and virulence factor genes exhibited by multidrug resistant (MDR)Acinetobacter baumannii, to analyze biofilm formation and to investigate clonal subtypes of isolate. Whole genome sequencing was done by Illumina NovaSeq 6,000 platform and multilocus sequence typing (MLST) was performed by Oxford and Pasteur typing schemes. Influence of imipenem and levofloxacin on biofilm formation was investigated in 96-well plates at 3 replicates. The strain was found to carry OXA-23, OXA-51-like, AmpC and TEM-1 beta-lactamases. The sequence of theblaOXA-51-likegene has been identified as ablaOXA-66. According to Pasteur MLST scheme the strain displayed ST2 allelic profile. However, based on Oxford MLST scheme this strain represents the new ST2121, as thegdhBgene has a single allelic mutation namely, thegdhB-227. It was determined that MDR isolate carriedbap, basABCDFGHIJ, csuA/BABCDE, bauABCDEF, plcD, pgaABCD, entE, barAB, ompA, abaIR, piT2EAFTE/AUBl, fimADT, cvaC, bfmR, bfmSvirulence genes. In our study imipenem induced the highest biofilm formation at a concentration of 32 µg/ml and levofloxacin at a concentration of 16 µg/ml. In conclusion, we detected a new MDRA. baumanniiST2121 clone harboringblaOXA-66gene that has been reported for the first time in Turkey.
Emergence of carbapenemase-producing and colistin resistant Klebsiella pneumoniae ST101 high-risk clone in Turkey
Authors: Hazırolan Gülşen , Karagöz Alper 
Published: November 2020

AbstractCarbapenemase-producing and colistin resistant Klebsiella pneumoniae has become a worldwide healthcare problem. This study describes molecular characterization of carbapenemase-producing and colistin resistant clinical K. pneumoniae isolates.A total of 93 non-replicate carbapenem and colistin resistant K. pneumoniae were recovered from clinical specimens in a university hospital during 2017–2019. Detection of blaOXA-48, blaKPC, blaNDM-1, blaIMP, blaVIM-1 and mcr-1, -2, -3, -4, -5, -6, -7, and -8 genes was performed by PCR. The bacterial isolates were assigned to clonal lineages by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST).All isolates harbored blaOXA-48 and only two isolates harbored blaOXA-48, and blaNDM-1 genes together. In colistin resistant K. pneumoniae, mcr-1 was detected in two (2.1%) isolates. Ninety three isolates of K. pneumoniae were categorized into three clusters and five pulsotypes. MLST revealed two different sequence types, ST101 (89/93) and ST147 (4/93).In our study ST101 was found to be a significantly dominant clone carrying blaOXA-48 and among our strains a low frequency of mcr-1 gene was determined. The emergence of colistin resistance was observed in K. pneumoniae ST101 isolates. ST101 may become a global threat in the dissemination of carbapenem and colistin resistance.
Academic mentoring projects between disadvantaged children and students. A method for the preparation of students for inclusive school settings
Authors: Heise Christina , Heinzel Friederike 
Published: November 2020

AbstractFuture teachers agree to meet a pupil once a week to engage in cultural, social and educational activities within the framework of two mentoring projects conducted at the University of Kassel. The students are supported at the University by an educational science seminar and by professional supervision (Garlichs et al., 2000; Heinzel et al., 2007). At the end of the project the students write a case study. Since 2015 these projects are part of PRONET, a government-funded bundle of various projects in the field of educational research, located at the University of Kassel, which are part of the nation-wide research initiative “Qualitätsoffensive Lehrerbildung”. This initiative aims at the improvement of teachers' education regarding inclusion by continuous evaluation of the projects. The mentoring projects promote students' inclusive attitude by stimulating their reflexive and cooperative skills and by raising their awareness for habitus-sensibility. Previous research has shown that mentoring projects can, for example, facilitate teachers' acceptance of heterogeneity of childhood experiences by providing insights into different social environments and by improving reflection on prejudices and stereotypes (Kottmann, 2014; Maas, 2007; Wenzler-Cremer, 2016). Following these findings, the actual research focuses on which kind of reflection students use and if they develop or strengthen inclusive orientations. With regards to data analysis, the qualitative content analysis of the case study is accompanied by sequential interpretation of audio statements, which the students produce at three points in time during their mentoring year. First results show that different kinds of reflection take place, that the students get confronted with inclusive and exclusive inconsistencies, and that they begin to reconceptualize ideas about normality.
ESX secretion system: The gatekeepers of mycobacterial survivability and pathogenesis
Authors: Roy Sadhana , Ghatak Debika , Das Payel , BoseDasgupta Somdeb 
Published: November 2020

AbstractMycobacterium tuberculosis, the causative agent of Tuberculosis has plagued humankind for ages and has surfaced stronger than ever with the advent of drug resistance. Mycobacteria are adept at evading the host immune system and establishing infection by engaging host factors and secreting several virulence factors. Hence these secretion systems play a key role in mycobacterial pathogenesis. The type VII secretion system or ESX (early secretory antigenic target (ESAT6) secretion) system is one such crucial system that comprises five different pathways having distinct roles in mycobacterial proliferation, pathogenesis, cytosolic escape within macrophages, regulation of macrophage apoptosis, metal ion homeostasis, etc. ESX 1–5 systems are implicated in the secretion of a plethora of proteins, of which only a few are functionally characterized. Here we summarize the current knowledge of ESX secretion systems of mycobacteria with a special focus on ESX-1 and ESX-5 systems that subvert macrophage defenses and help mycobacteria to establish their niche within the macrophage.
Economic growth and income distribution implications of public spending and tax decisions
Authors: Darvas Zsolt 
Published: November 2020

AbstractBoth the level and composition of public expenditures and revenues have implications for economic development, as argued by the ‘fiscal multiplier’ and the ‘quality of public finance’ literature. Public finance decisions also influence the distribution of income. By reviewing the literature, I argue for a fair distribution of income as reflected in low income inequality, not particularly because of the impact of income inequality on long-term growth (which is a controversial issue), but primarily because income inequality typically implies inequality of opportunity. European Union countries have very diverse public finance structures and different levels of effectiveness, and there is room for improvement in growth and equality impacts in all countries. A general guideline would be that the most effective approach comprises progressive taxes and inheritance taxes, spending on education, health and public infrastructure, and better government effectiveness. At the height of the 2008 global and the subsequent European financial and economic crises, the fiscal consolidation strategies of EU countries largely relied on cutting public investment and social spending (except pensions), which is the opposite of what is suggested in the literature. Better fiscal rules and good fiscal institutions are needed to safeguard growth- and distribution friendly expenditures in a crisis.
Sharing communities – Community currency in the sharing economy
Authors: Szemerédi Eszter , Tatay Tibor 
Published: November 2020

AbstractFor the further development and more efficient operation of the sharing economy, a fast and inexpensive peer-to-peer payment system is an essential element. The aim of this study is to outline a prototype that ensures the automation and decentralization of processes through smart contracts without blockchain technology. The model has been built based on the narrative that a community currency created through smart contracts can promote genuine practices of sharing as opposed to the profit-oriented approach that most of the currently operating sharing economy platforms have. Features of the model, such as ease of use, high-speed transactions without transaction cost are benefits that can provide a more efficient alternative to the traditional or to the cryptocurrency-based centralized sharing economy platforms.
Human Gait Cycle Analysis Using Kinect V2 Sensor
Authors: Müller Péter , Schiffer Ádám 
Published: November 2020

Examining a human movement can provide a wealth of information about a patient’s medical condition. The examination process can be used to diagnose abnormal changes (lesions), ability development and monitor the rehabilitation process of people with reduced mobility. There are several approaches to monitor people, among other things with sensors and various imaging and processing devices. In this case a Kinect V2 sensor and a self-developed LabView based application was used, to examine the movement of the lower limbs. The ideal gait pattern was recorded in the RoboGait training machine and the measured data was used to identify the phases of the human gait. During the evaluation, the position of the skeleton model, the associated body joints and angles can be calculated. The pre-recorded ideal and natural gait cycle can be compared.With the self-developed method the pre-recorded ideal and natural gait cycle can be compared and processed for further evaluation. The evaluated measurement data confirm that a reliable and mobile solution for gait analysis has been created.
Present Condition Analysis and Design of Sewer Collector Recovery
Authors: Csicsaiová Réka , Marko Ivana , Hrudka Jaroslav , Škultétyová Ivona , Stanko Štefan 
Published: November 2020

The aim of the study is to assess the hydraulic capacity of the sewer network and sewer collector recovery in the urban catchment area of Trnava.The analysis focuses on the evaluation of situations with different precipitation frequencies. Elaboration consists of modeling the current state of the assessed sewer collector B and subsequent loading of this collector by several block rainfalls. Based on the results of the analysis, the recovery of the sewer network proposed.
News Sentiment in Bankruptcy Prediction Models: Evidence from Russian Retail Companies
Authors: Makeeva Elena , Sinilshchikova Maria 
Published: November 2020

This study is aimed at investigating the application of news sentiment analysis to bankruptcy prediction models in the context of the Russian retail sector.
We analyse 190 companies: 95 Russian retail companies that went bankrupt in 2015-2019, and 95 non-defaulting analogue companies. This figure was attained from a larger pool of 312 companies retrieved from the Spark database on the basis of analysis of relevant financial data and further validated by the presence of pertinent news media coverage within 3 years of default date. The methodological base of this analysis is the logistic regression approach, used as a benchmark model, and several machine learning models: random forest, support vector machine, and multilayer perceptron.
The predictor set applied consists of 34 financial variables and sentiment variables, aggregated using the ‘bag-of-words’ from a total sample of 4877 news articles, from more than 800 distinct online resource locations. We establish a set of hypotheses based on a review of existing literature in the area, and evaluate their accuracy on the basis of our technical analysis.
Our results show that sentiment variables are statistically significant, and that adding sentiment variables improves the performance of bankruptcy prediction models. Also, the results indicate some reference characteristics of companies in terms of word-choice and descriptions in the news, indicating word choices correlated with financially stability and those correlated with financially instability.
Respuesta Autonómica de estrés en estudiantes de Doctorado
Authors: Clemente-Suarez Vicente Javier , Herrera-Mendoza Ketty , Montañez-Romero Miguel , Navarro Maria Camila , Crespo-Ribera William , Vargas Carlos , Arroyo-Alvis Katty , Morales Marcos , Fábregas Luis , Cadena-Díaz Ivan , Cala-Uribe Juliana 
Published: November 2020

La sustentación del proyecto de tesis doctoral es una situación que genera estrés con múltiples manifestaciones físicas y comportamentales. En este artículo se analizó la respuesta autonómica de estrés en estudiantes de doctorado en una defensa de su proyecto de tesis doctoral. El estudio conto con una muestra de 16 estudiantes de doctorado, a quienes se les analizó la variabilidad de la Frecuencia Cardiaca en estado basal y en la defensa de su proyecto para evaluar su respuesta autonómica de estrés. Se evidencio que los estudiantes presentaron un aumento en la modulación autonómica simpática en la exposición a la defensa de su proyecto de tesis doctorado, debido a la disminución de los valores de Porcentaje de diferencias entre R-R adyacentes normales intervalos mayores de 50 ms (PNN50) = 15.2±13.7 y la dispersión longitudinal de los puntos, respectivamente, obtenidos a partir del gráfico de Poincaré (SD1) = 34.0±22.2 y SD2= 77.1±42.8 durante la defensa de su proyecto de tesis. Podemos concluir que con base en los resultados obtenidos el incremento de la modulación simpática, por parte de los estudiantes de estudiantes de doctorado evidencia una baja capacidad adaptativa por parte de ellos a situaciones de alto nivel de estrés como sería la defensa de la propuesta de tesis doctoral, aspecto este que autores previos han relacionado con impedimentos en el rendimiento académico en estudiantes pregrado y posgrado pero que no están inmerso dentro de una actividad investigativa lo cual pone de manifiesto la necesidad de diseñar programas de regulación y entrenamiento del control y manejo del estrés en estudiantes de pregrado y posgrado. Esto permitirá mejorar los resultados académicos en contextos de educación superior como el evaluado en el presente trabajo.
Is gender a determinant for the outcome of laparoscopic cholecystectomy?
Authors: Bahadur Akshay , Bisht S. D. , Rathi Yanshul , Shukla Ashish , Aggarwal Aman 
Published: November 2020

Background: Currently, laparoscopic cholecystectomy is one of the most desirable procedures to treat symptomatic gallstone disease. Yet, various risk factors govern its conversion to open surgery. The impact of male sex as a risk factor for conversion has been a questionable issue. The study aimed to evaluate the role of male sex on outcomes of laparoscopic cholecystectomy.Methods: As per inclusion and exclusion criteria, medical records of all the patients aged 18-70 years who underwent elective LC for a period of 14 months were accessed retrospectively. Data related to patients’ demographic details, intra-operative and post-operative findings was recorded and subjected to analysis.Results: Out of 232 selected cases, 17.67% were males and 82.32% were females. Mean age in both gender groups was similar (p=0.139). Body mass index was also found to be similar in both the groups (p=0.232). There was no significant difference (p=0.85) in the mean operative time between men (29.37±9.29) and women (28.88±15.66). Conversion to open surgery was seen only in female group (1.57%) but it is not significantly from the male group (p=0.42). No significant difference was observed in both groups regarding unwanted intra-operative events (p=0.231) and post-operative complications (p=0.70) and post- operative stay (p=0.50).Conclusions: This study suggests that male gender may not be considered as an independent risk factor for outcome of laparoscopic cholecystectomy. However, extensive research in future may cast further light on this issue.
Isolated lingual cysticerscosis: a rare case report
Authors: Rajbhandari Pradeep , Shrestha Bijaya Kumar , Shrestha Roshani 
Published: November 2020

<p class="abstract">Taenia solium completes its life cycle in two hosts. Generally, cysticercosis results from accidental ingestion of the eggs of taenia solium through faeco‐oral contamination or autoinfection cysticercosis is commonly found in muscular and subcutaneous tissues. Central nervous system and eye are commonly affected. Despite abundant intermuscular tissue in oral cavity, it is uncommon site for cysticercosis because of high muscular activity and metabolic rate of oral tissues. We present a case of a 21-year-old male, presented with painless solitary swelling in the ventral aspect of tip of tongue at the centre. Excision of the swelling was done followed by histopathological examination. The histopathological examination revealed cysticercosis cellulosae in tongue musculature. Histopathological picture showed cysticercus larva surrounded by a double layered membrane. The patient was given albendazole 200 mg TDS for 30 days. One-year follow-up showed no signs of recurrence. Lingual cysticercosis usually presents as diagnostic dilemma. Complete excision along with histopathological examination is diagnostic. Infestation in this region is relatively mild as compared to ocular or neurocysticercosis. However, the patients should be examined thoroughly and followed up for possible concurrent ophthalmologic and neurologic involvements as well. </p>
Pharmacy professionals’ preparedness to use Mental Health First Aid (MHFA) behaviors
Authors: Witry Matthew J. , Fadare Olajide , Pudlo Anthony 
Published: November 2020

Background: There is a need to train healthcare professionals to provide first aid to people experiencing a mental health crisis. Research testing the association between Mental Health First Aid (MHFA) training and the use of MHFA behaviors could provide evidence of program effectiveness in the pharmacy setting.
Objectives: The objectives of this study were to measure the preparedness of pharmacy professionals to function in a MHFA role, and compare preparedness and the use of MHFA behaviors based on demographic characteristics.
Methods: Pharmacists and student pharmacists attended MHFA training under a multi-state pharmacy initiative in 2018. An anonymous electronic survey was administered to 227 participants using 4 contacts in May to June, 2019. The survey evaluated if participants had recommended MHFA to others, their preparedness to engage in MHFA behaviors (13 items), and their frequency of performing a set of MHFA behaviors (7 items). Descriptive statistics, bivariate analysis, and ANOVA were used to describe the sample and compare these variables across groups.
Results: The analysis was based on 96 responses (42.3%). Almost all respondents (96%) had recommended MHFA training to others. Respondents reported that the training program prepared them to provide a range of MHFA behaviors for multiple mental health conditions, particularly for depression and anxiety. Participants most often reported asking about a distressed mood and listening non-judgmentally. Almost half of participants had asked someone if they were considering suicide and a similar percent had referred someone considering suicide to resources. Those reporting the highest levels of preparedness engaged in significantly more MHFA behaviors than those with lower levels of preparedness (p=0.017). Preparedness and use of MHFA behaviors were not significantly associated with respondent demographic characteristics.
Conclusion: These data suggest that pharmacy professionals who had MHFA training felt prepared to engage in MHFA and many used behaviors like asking about suicide and making referrals since being trained in MHFA. Research is warranted to better understand what makes someone feel maximally prepared to use MHFA behaviors compared to lower feelings of preparedness.
ORF3a mediated-incomplete autophagy facilitates SARS-CoV-2 replication
Authors: Qu Yafei , Wang Xin , Zhu Yunkai , Wang Yuyan , Yang Xing , Hu Gaowei , Liu Chengrong , Li Jingjiao , Ren Shanhui , Xiao Zixuan , Liu Zhenshan , Wang Weili , Li Ping , Zhang Rong , Liang Qiming 
Published: November 2020

Abstract
SARS-CoV-2 is the causative agent for the COVID-19 pandemic and there is an urgent need to understand the cellular response to SARS-CoV-2 infection. Beclin-1 is an essential scaffold autophagy protein that forms two distinct subcomplexes with modulators Atg14 and UVRAG, responsible for autophagosome formation and maturation, respectively. In the present study, we found that SARS-CoV-2 infection triggers an incomplete autophagy response, elevated autophagosome formation but impaired autophagosome maturation, and declined autophagy by genetic knockout of essential autophagic genes reduces SARS-CoV-2 replication efficiency. By screening 28 viral proteins of SARS-CoV-2, we demonstrated that expression of ORF3a alone is sufficient to induce incomplete autophagy. Mechanistically, SARS-CoV-2 ORF3a interacts with autophagy regulator UVRAG to facilitate Beclin-1-Vps34-Atg14 complex but selectively inhibit Beclin-1-Vps34-UVRAG complex. Interestingly, although SARS-CoV ORF3a shares 72.7% amino acid identity with the SARS-CoV-2 ORF3a, the former had no effect on cellular autophagy response. Thus, our findings provide the mechanistic evidence of possible takeover of host autophagy machinery by ORF3a to facilitate SARS-CoV-2 replication and raises the possibility of targeting the autophagic pathway for the treatment of COVID-19.