bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inclusion of plant immunity inducers in the fruit crops protection system for the purpose of reducing the pesticide load
Authors: Ya Ayba L , Karpun N N , Mikhailova Ye V , Pantiya G G 
Published: December 2020

Abstract
One of the new environmentally friendly areas of plant protection is the use of natural protective mechanisms in protection against phytopathogens. The purpose of this study was to evaluate the role of plant immunity inducers of various chemical nature (poly-beta-hydroxybutyric acid, arachidonic acid ethyl ester and chitosan lactate) when included in peach and apple protection systems against diseases dominating in the region of wet subtopics of Russia and Abkhazia (leaf curl and scab, respectively). Studies on peach against leaf curl were conducted on the variety ‘Redhaven’ (Sochi, Russia) in 2014-2016, and on the apple tree against scab on the variety ‘Golden Rangers’ (Gulripshi district, Abkhazia) in 2016-2019. The standard was the peach and apple tree chemical protection system adopted in the region. We studied the effectiveness of tank mixtures of plant immunity inducers (Albit®, Immunocytophite®, Ecogel®) with half dosages of pesticides used in the standard. The biological effectiveness of all mixtures with plant immunity inducers on peach exceeded the standard, and on the apple tree was at the standard level. The best results were obtained in variants with Ecogel® and Albit®. In variants with plant immunity inducers crop yields were 23-60% higher than in the control.
Monitoring productivity of Kazakh Bactrian and Arvana camels of Kazakhstan population
Authors: Baimukanov A , Alibayev N , Semenov V , Ermakhanov M , Abuov G 
Published: December 2020

Abstract
The purpose of the study is to perform monitoring of camels of Kazakh Bactrian and Arvana dromedary breeds in the South West region of Kazakhstan; to determine perspective genotypes of purebred camels according to their dairy productivity. The study of class composition of the selected Arvana female camels of the 1st lactation with a milk yield of not less than 1950 kg allowed identifying 21.8% of Elite Class and 78.2% of Class I among 125 animal units. Kazakh Bactrian female camels of the first lactation are also selected with the yield of 1000 kg minimum in the number of 309 animals in the basic collective farms of camel breeding zones. It was found out that of 309 animals, 23.0% compose the Elite Class and 77.0% make the Class I. The estimation of Kazakh Bactrian female camels according to the milking capacity coefficient allowed determining that the optimal parameter for selection is Rank 1.5-1.9. It was found that in female camels according to the fertility index of Rank 1 (up to 42%), colt safety is reliably higher that compared with female camels of the same age with Rank 2 (42-47%) and Rank 3 (47% and higher).
Biological and production capacities of Kazakh Bactrian camels of various pedigrees
Authors: Baimukanov D A , Semenov V G , Zh Iskhan K 
Published: December 2020

Abstract
Kazakh Bactrian (Camelus bactrianus) camels have biological and productive features. So far, there are no scientifically based data on modern breeding practices. The analysis of some peculiarities of Kazakh Bactrian female camels of various pedigrees and determination of their production features are of great importance to develop a productive camel breeding. In this paper some biological peculiarities of Kazakh Bactrian females and their production qualities are determined. It was found that with the decrease of pedigree fraction of Kazakh Bactrian camels the respiration rate increases up to the limit of the physiological standard, body temperature and pulse rate did not change with changing the pedigree of Kazakh Bactrian camels. The recorded data confirm that female camels are clinically healthy in all the physiological parameters. The data show the high level of changes in blood corpuscle concentration, which is 11% higher in red blood cells and 19% higher in white blood cells.
Comparative evaluation of potato varieties bred in Russia and Belarus
Authors: Filippova S , Eliseeva L , Selivanov A , Alexandrova A , Mefodiev G 
Published: December 2020

AbstractThe paper contains findings on comparative evaluation of potato varieties of varied times to maturity bred in Russia and Belarus. The study identified potato varieties that are best adapted to the soil and the climate of the Volga-Vyatka region. Samba and Gulliver varieties deliver the highest yields amongst Russia-bred variety – 53.7 and 50.0 t/ha. These cultivars had the most smooth-skinned tubers without cracks and other damage. Amongst Belarus-bred cultivars, Breeze cultivar stood out – 50.1 t/ha. Samba, Gulliver, Yanka and Zorachka cultivars had the best gustatory qualities. Tuber analysis showed that 82% of Charoite tubers fall into seed grade. Gulliver and Pennant varieties produced large amount of seed tubers – 69.7 and 69% of the total number of tubers, respectively. Samba, Gulliver, Yanka and Zorachka were the tastiest.
Influence of planting density of micro-plants on the number of potato mini-tubers
Authors: Filippova S , Eliseeva L , Isaev O , Ivanova T , Eliseev I , Shashkarov L , Malov N 
Published: December 2020

Abstract
For the first time in the conditions of the Volga-Vyatka region of the Russian Federation, we determined the parameters of planting micro-plants for the output of potato mini-tubers. The study has shown that to increase the yield of mini-tubers of potatoes, it is necessary to develop an optimal method for planting micro-plants that is most suitable for each variety. Some potato varieties, such as Reggae and Samba, produce more mini-tubers when the planting density increases. Whereas Bellarosa potato plants will produce more mini-tubers if the nutrition area for each plant is increased by reducing planting density. In potato varieties Reggie and Samba, by increasing the density of planting, the yield of mini-tubers increases. For the Bellarosa variety, a decrease in the planting density of micro-plants is required.
Assessment influence of recombinant interleukin-2 and polyoxidonium to physiological condition and formation of non-specific resistance of calves 30 days of age
Authors: Klyapnev A V , Velikanov V I , Terentev S S , Gorina A V , Sletov A O , Klyapnev N V , Dunaevskaya A A , Trunova E A 
Published: December 2020

Abstract
The basis of health and the possibility of realizing productive potential of farm animals are high level of natural resistance and immune status of their body. One of the reserves for increasing the productivity of young cattle is increase their resistance, especially in conditions of unbalanced feeding of mother cows and violations of the animal housing. The study period of 20-30 days of age of the calves was chosen taking into account the fact that during this period they have reduced resistance to infectious diseases, because immunoglobulins received with maternal colostrum, breaking by this age, and their own are just beginning to be produced. Active immunity is formed only by 1.5-2 months of age. The calves organism needs at this time stimulation of the immune system and nonspecific resistance, and the effect of immuno modulating drugs is more pronounced. The objective of the study was to assess the effect of recombinant interleukin-2 and polyoxidonium on the physiological state, morphological composition of the blood and the formation of nonspecific resistance of calves. The calves of the first experimental group were parenterally injected with recombinant interleukin-2. The calves of the second experimental group were injected polyoxidonium. The calves of the control group were injected physiological saline. The experimental part was performed on calves at farming enterprise Dalnekonstantinovsky district of Nizhny Novgorod region, Russia. The experimental work was conducted in the spring.
Regional aspects of food security
Authors: Filippova S P , Gordeeva L G , Abrosimova M S , Litvinova O V , Semenova A N , Nesterova N V 
Published: December 2020

Abstract
In the present work, we assessed the level of food security in the Chuvash Republic according to the level of physical availability and affordability as well as sufficiency of food products. Adequacy of consumption is determined by comparing the actual volume of product consumption with the rates authorized by the Ministry of Health of the Russian Federation. The analysis revealed a high level of physical availability of food in the region that it is not supported by a sufficient economic basis. As a result, a certain part of the population does not have the opportunity to receive foodstuff in quantity and quality within permissible recommended rates. Solution of the food security problem requires a systematic approach based on the development of agricultural production and solution of the social and economic problems aimed to improve the household quality of life.
A novel study on augmented physical parameters of nickel doped stannic oxide film
Authors: Babu A Victor , Murugan S , BerniceVictoria D C , Gnanamuthu S Joshua , Ravichandran S 
Published: December 2020

Abstract
A noval study on the fabrication of virgin and nickel (Ni) doped stannic oxide (SnO2) thin films with different doping extent have been conducted to augment the properties of stannic oxide thin films to incorporate into the electric cell which utilizes sun’s energy. The influence of the Ni doping with various extents on the structural, optical and magnetic properties of the different synthesized samples of stannic oxide thin films are investigated byX-ray diffraction (XRD), Scanning electron microscopy (SEM), UV-Visible spectrophotometer and Vibrating Sample Magnetometer (VSM). All the fabricated samples of SnO2: Ni(1at%, 2at%, 3at% and 4at%) exhibited tetragonal structure of stannic oxide. The fusion of Ni into the stannic oxide lattice makes imperfection in the crystal and the presence of additional peaks confirms that the nickel domination is well observed. Increase in the extent of Ni doping causes diminution in optical band gap. The magnetic study reveals that the ferromagnetic signal is gradually enhanced with augment in doping concentration.
Quantum correlations in

PT

-symmetric systems
Authors: Roccati Federico , Lorenzo Salvatore , Massimo Palma G , Landi Gabriel T , Brunelli Matteo , Ciccarello Francesco 
Published: December 2020

Abstract
We study the dynamics of correlations in a paradigmatic setup to observe

PT

-symmetric physics: a pair of coupled oscillators, one subject to a gain one to a loss. Starting from a coherent state, quantum correlations (QCs) are created, despite the system being driven only incoherently, and can survive indefinitely. Both total and QCs exhibit different scalings of their long-time behavior in the

PT

-broken/unbroken phase and at the exceptional point (EP). In particular,

PT

symmetry breaking is accompanied by non-zero stationary QCs. This is analytically shown and quantitatively explained in terms of entropy balance. The EP in particular stands out as the most classical configuration, as classical correlations diverge while QCs vanish.
Mechanical properties of colloidal crystals at fluid interfaces
Authors: Buttinoni Ivo , Dullens Roel P A 
Published: December 2020

Abstract
We characterise the local mechanical properties of two-dimensional colloidal crystals with hexagonal symmetry assembled at the flat interface between oil and water. Our experiments elucidate the conditions under which the material behaves isotropically, as opposed to those where the microstructure plays a major role. Brownian fluctuations are used to extract the stiffness of the lattice under the continuum approximation, whereas at larger displacements, obtained by optically driving one particle through the structure, the mechanical resistance of the lattice depends on both the area fraction and the direction of the applied force. Remarkably, the minimum resistance does not necessarily correspond to a probe being driven between neighbours, i.e. at 30° with respect to the crystal axes.
The moving spotlighter’s way of ‘unfreezing the spotlight’
Authors: Jhou Nihel H 
Published: December 2020

AbstractIn their 2020 paper ‘Unfreezing the spotlight’, Correia and Rosenkranz argue that the spotlight theory – the mix of the view that, always, everything always exists and the view that there is a metaphysically robust property of presentness for times – is sufficient for temporal passage, and that the fact ‘that this robust property of presentness attaches to different times as time goes by … is unnecessary’. In this paper, I shall reveal that Correia and Rosenkranz’s spotlight theory is a moving spotlight theory in disguise.
Identification of differentially expressed gene modules in heterogeneous diseases
Authors: Zolotareva Olga , Khakabimamaghani Sahand , Isaeva Olga I , Chervontseva Zoe , Savchik Alexey , Ester Martin 
Published: December 2020

Abstract

Motivation
Identification of differentially expressed genes is necessary for unraveling disease pathogenesis. This task is complicated by the fact that many diseases are heterogeneous at the molecular level and samples representing distinct disease subtypes may demonstrate different patterns of dysregulation. Biclustering methods are capable of identifying genes that follow a similar expression pattern only in a subset of samples and hence can consider disease heterogeneity. However, identifying biologically significant and reproducible sets of genes and samples remain challenging for the existing tools. Many recent studies have shown that the integration of gene expression and protein interaction data improves the robustness of prediction and classification and advances biomarker discovery.

Results
Here, we present DESMOND, a new method for identification of Differentially ExpreSsed gene MOdules iN Diseases. DESMOND performs network-constrained biclustering on gene expression data and identifies gene modules—connected sets of genes up- or down-regulated in subsets of samples. We applied DESMOND on expression profiles of samples from two large breast cancer cohorts and have shown that the capability of DESMOND to incorporate protein interactions allows identifying the biologically meaningful gene and sample subsets and improves the reproducibility of the results.

Availability and implementation
https://github.com/ozolotareva/DESMOND.

Supplementary information
Supplementary data are available at Bioinformatics online.
Lateralization in monogamous pairs: wild geese prefer to keep their partner in the left hemifield except when disturbed
Authors: Zaynagutdinova Elmira , Karenina Karina , Giljov Andrey 
Published: December 2020

AbstractBehavioural lateralization, which reflects the functional specializations of the two brain hemispheres, is assumed to play an important role in cooperative intraspecific interactions. However, there are few studies focused on the lateralization in cooperative behaviours of individuals, especially in a natural setting. In the present study, we investigated lateralized spatial interactions between the partners in life-long monogamous pairs. The male-female pairs of two geese species (barnacle, Branta leucopsis, and white-fronted, Anser albifrons geese), were observed during different stages of the annual cycle in a variety of conditions. In geese flocks, we recorded which visual hemifield (left/right) the following partner used to monitor the leading partner relevant to the type of behaviour and the disturbance factors. In a significant majority of pairs, the following bird viewed the leading partner with the left eye during routine behaviours such as resting and feeding in undisturbed conditions. This behavioural lateralization, implicating the right hemisphere processing, was consistent across the different aggregation sites and years of the study. In contrast, no significant bias was found in a variety of geese behaviours associated with enhanced disturbance (when alert on water, flying or fleeing away when disturbed, feeding during the hunting period, in urban area feeding and during moulting). We hypothesize that the increased demands for right hemisphere processing to deal with stressful and emergency situations may interfere with the manifestation of lateralization in social interactions.
Impact of Diet and Moisture Content on the Development ofMusca domestica(Diptera: Muscidae)
Authors: Kökdener Meltem 
Published: December 2020

AbstractThe purpose of this study was to investigate the effects of different diets and moisture levels on the life-history parameters of house flies. The experiments were carried out at the Animal Physiology Research Laboratory of Ondokuz Mayıs University in 2019. House fly larvae were reared on three diets (wheat bran, fish meal poultry meal) with 50, 60, 70, 80, and 90% moisture levels. The effects on the life-history parameters were compared with multivariate analysis of variance (MANOVA). Our results show significant differences in size, weight, survivorship, and development across the diet types, and moisture content tested. In this study, the larval development period was shortest when the moisture content of the poultry meal diet was 50%. Larvae of Musca domestica Linnaeus, 1758 (Diptera: Muscidae) did not develop on any diets at 90% moisture. The wheat bran diet was superior to the other diets for all parameters tested.
Transcatheter aortic valve implantation for tricuspid aortic valve with a calcium bridge between the cusps: a case report
Authors: Nakashima Masaki , Tada Norio , Hata Masaki 
Published: December 2020

Abstract

Background
Indications for transcatheter aortic valve (AV) implantation (TAVI) have been extended to patients with challenging anatomical features such as a bicuspid AV. However, no case reports of TAVI for tricuspid AV with a ‘calcium bridge’ have been published.

Case summary
We report the case of an 87-year-old woman with severe symptomatic aortic stenosis (AS). Pre-procedural multidetector computed tomography (MDCT) showed a calcium bridge between the non-coronary and left cusps. Although these cusps appeared to be fused together in the centre by the calcium bridge, the commissure area between the fused cusps appeared to normally open. We cracked apart the calcium bridge from the commissure area using balloon aortic valvuloplasty, which was guided by transoesophageal echocardiography. Subsequently, we successfully implanted a balloon-expandable transcatheter heart valve (THV).

Discussion
To our knowledge, this is the first report of TAVI for a tricuspid AV with a ‘calcium bridge’ between the non-coronary and left cusps. In our patient, the unique structure of cusp fusing in the centre seemed to be caused by an acquired atherosclerotic process, as documented using a contemporary technique, i.e. MDCT. Cracking the calcium bridge with a balloon aortic valvuloplasty ensured that the THV adequately expanded. Severe AS caused by a calcium bridge may be treated with detailed evaluation of the AV morphology together with a procedural strategy planning.
Development and Validation of a UPLC-DAD Method for the Simultaneous Quantification of Eight Antihypertensive Drugs in the Pharmaceutical Matrix
Authors: El Karbane Miloud , Benchekroun Yassine Hameda , Abousalih Fatima Zahra , Bennani Ismail , Azougagh Mohamed , Saffaj Taoufiq , Bouatia Mustapha 
Published: December 2020

Abstract

Background
Hypertension is a critical health problem; it is a prevalent risk factor for cardiovascular disease. Many treatments to combat hypertension are available, however many patients are resistant to the standard therapeutic approaches. The association of two or more substances in a fixed-dose combination is effective and tolerated as a substitute for the standard therapeutic approach.

Objective
The new ultra performance liquide chromatography method was developed and validated to assay a combination of eight antihypertensive drugs including a diuretic: hydrochlorothiazide, dihydropyridine calcium channel blocker: Amlodipine and angiotensin II type 1 receptor blockers (sartans): valsartan, candesartan, eprosartan, olmesartan, losartan, and irbesartan in the pharmaceutical matrix.

Methods
Chromatographic separation was performed on an Acquity® UPLC C18 1.7 µm 2.1 × 100 mm column, with a gradient of buffer solution and acetonitrile, in the proportion of (80:20 v/v).

Results
Good resolution was obtained, and an optimal analysis time of less than 5 min was achieved. The method was validated according to the International Conference on Harmonization guidelines following the classical approach and accuracy profile, and it is shown to be suitable for intended applications. The method was successfully used for quality control laboratories and the determination of these drugs combinations in pharmaceutical dosage forms.
The Quantification of Oxycodone and Its Phase I and II Metabolites in Urine
Authors: Truver Michael T , Jakobsson Gerd , Chermà Maria D , Swortwood Madeleine J , Gréen Henrik , Kronstrand Robert 
Published: December 2020

Abstract
The purpose of this research was to develop and validate an analytical method for the detection and quantification of noroxymorphone-3β-D-glucuronide (NOMG), oxymorphone-3β-D-glucuronide (NOMG), noroxymorphone (NOM), oxymorphone (OM), 6α-oxycodol (αOCL), 6β-oxycodol (βOCL), noroxycodone (NOC) and oxycodone (OC) in urine by liquid chromatography tandem mass spectrometry to be used in a human study. The method was validated according to the Academy Standards Board Standard Practices for Method Development in Forensic Toxicology. The method was then applied to a single-dose pilot study of a subject. Urine samples were collected from the subject after ingesting 10-mg OC as an immediate-release tablet. Additionally, urine specimens (n = 15) that had previously been confirmed positive for OC were analyzed using the validated method. The calibration range for NOMG and OMG was 0.05–10 μg/mL; for all other analytes, it was 0.015–10 μg/mL. Validation parameters such as bias, precision, carryover and dilution integrity, all met the validation criteria. After the method was validated, urine samples from the first subject in the controlled dose study were analyzed. It was observed that OC, NOC and OMG contained the highest concentrations and were present in either the 0.5 or 1 h void. NOC and OMG were detected until the 48 h collection, while OC was detectable till the 24 h collection. Time to reach maximum concentration (Tmax) in the urine was achieved within 1.5 h for OC and within 3 h for NOC and OMG. Maximum concentration (Cmax) in the urine for OC, NOC and OMG was 3.15, 2.0 and 1.56 μg/mg, respectively. OC concentrations in authentic urines ranged from 0.015 to 12 μg/mL. Ranges for NOMG and OMG were 0.054–9.7 μg/mL and 0.14–67 μg/mL, respectively. A comprehensive method for the quantification of NOMG, OMG, NOM, OM, αOCL, βOCL, NOC and OC in urine was optimized and met the validation criteria. The concentrations of NOMG and OMG presented in this study provide the details needed in the forensic community to better comprehend OC pharmacokinetics.