bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding the effects of perceived organizational support and high-performance work systems on health harm through sustainable HRM lens: a moderated mediated examination
Authors: Chillakuri Bharat , Vanka Sita 
Published: May 2020

PurposeThe purpose of this paper is to provide an empirical investigation into the mediating effect of high-performance work systems (HPWS) on health harm (HH). The paper also examines the role of perceived organizational support (POS) and its indirect effect on work intensification (WI) and HH through HPWS. Further, the implications of the HH on individuals, organizations, families and societies are also presented. Recognizing the need for sustainable human resource management (HRM) practices that drive employee well-being and reducing HH is also highlighted.Design/methodology/approachData for the study were collected using four established scales. The data collected from 345 executives were analyzed using the SPSS 25.0 Version and Amos 21.0.FindingsThe study confirmed that work intensification causes HH. The results also indicate the significant mediation of HPWS and the moderation of POS between WI and HH, thus suggesting the inevitability of HR intervention for implementing sustainable HRM practices, which reduce the negative harm of the work.Research limitations/implicationsData were collected from executives working in IT organizations in India. However, IT work exhibits broadly similar technology/platforms across the world and hence, applicable to the other contexts as well.Practical implicationsThe study suggests that organizations should formulate policies and initiate interventions toward the care of employees, motivating toward higher performance and support them to prevent HH of work. It is difficult to categorize what comprises the care of employees in the current context of HPWS and treating employees as an end in itself. Generally, it is seen in terms of health and safety, work–life balance, remuneration, workload, job role and job design. People are core to sustainable development, and the HR must design and develop systems so that the organization can retain a healthy and productive workforce from a sustainability perspective. Moreover, sustainable work performance is a function of high resource levels of employees (energy, time and competences) and the allocation of resources, leading to resource regeneration. Hence, organizations need to source from a variety of sources and balance it for the sustainable performance of employees.Originality/valueThe HRM literature reveals the positive effect of POS on employee health, but studies that investigated the adverse impact of POS are notably absent. The study bridges this gap and is novel, as it explores the moderating role of POS on HPWS and HH and reaffirms the need for building sustainable organizations and sustainable HRM practices. Moreover, the paper provides contextual support to the literature, where studies relating to sustainable HRM practices in developing countries like India are absent.
Digital marketing capabilities in international firms: a relational perspective
Authors: Wang Fatima 
Published: May 2020

PurposeDifferences in digital adoption between firms call for a clearer conceptualization of digital marketing capabilities (DMCs). The purpose of this paper is twofold: (1) to offer a conceptualization of DMCs from a relational dynamic capabilities perspective and (2) to explore performance outcomes of DMCs for international firms, taking into account firm size and entrepreneurial orientation.Design/methodology/approachA survey on a sample of 167 international firms is used and analyzed using hierarchical regression.FindingsDMCs contribute positively to performance. Firms with greater entrepreneurial orientation leverage DMCs more effectively and have better performance. Small firms with strong digital capabilities perform as well as medium-sized firms. Large firms perform marginally better than small and medium-sized firms.Research limitations/implicationsThis paper complements previous IB studies that only study customer-related or supplier- and channel-related IT adoption. It is based on a more holistic conceptualization of DMCs, and draws on market sensing, customer-linking, customer retention, supplier relationship and channel bonding capabilities. It offers new empirical evidence for the positive impact of DMCs on firm performance. It also contributes to small and medium-sized enterprise and digital entrepreneurship literature by comparing the performance outcomes of DMCs for different size firms with varying degrees of entrepreneurial orientation.Practical implicationsThis study provides implementable measures of DMCs. The findings encourage firms to develop entrepreneurial orientation alongside DMCs.Originality/valueThis paper presents DMCs as relational dynamic capabilities and shows the moderating effect of entrepreneurial orientation and firm size on the DMCs–performance relationship.
Market power and cost efficiency in the African banking industry
Authors: Asongu Simplice , Nting Rexon , Nnanna Joseph 
Published: May 2020

PurposeIn this study, we test the so-called “Quiet Life Hypothesis” (QLH), which postulates that banks with market power are less efficient.Design/methodology/approachWe employ instrumental variable Ordinary Least Squares, Fixed Effects, Tobit and Logistic regressions. The empirical evidence is based on a panel of 162 banks consisting of 42 African countries for the period 2001–2011. There is a two-step analytical procedure. First, we estimate Lerner indices and cost efficiency scores. Then, we regress cost efficiency scores on Lerner indices contingent on bank characteristics, market features and the unobserved heterogeneity.FindingsThe empirical evidence does not support the QLH because market power is positively associated with cost efficiency.Originality/valueOwing to data availability constraints, this is one of the few studies to test the QLH in African banking.
Determinants of CSR disclosure: an evidence from India
Authors: P. Fahad , K.B. Nidheesh 
Published: May 2020

PurposeThis paper aims to undertake an empirical investigation on firm characteristics determining corporate social responsibility (CSR) disclosure and its subcategories such as environmental, social and governance disclosures.Design/methodology/approachThe sample consisted of listed companies in BSE 500 index for a period of 10 years from 2007 to 2016. Panel data regression method is used for the analysis. Seven variables are analyzed, namely, firm age, financial leverage, firm size, foreign ownership, promoter ownership, export performance, innovation and firm popularity.FindingsThe result shows that firm age and financial leverage are positively influencing CSR, environmental and social disclosure score but both are negatively influencing governance score. Firm size is positively associated with all four disclosure scores. Among ownership variables, foreign ownership shows a positive influence and promoters ownership shows a negative influence towards CSR, environment and social disclosures. No association is found between both ownership variables and governance disclosure score. Further analysis also finds that there is a difference in this relationship during crisis period.Research limitations/implicationsThe study focuses only on listed companies in Indian capital market. In terms of implication, theoretical bases discussed in the literature review and hypotheses development are mostly validated.Practical implicationsThe findings are important for the firm, stakeholders and policymakers. A firm may think about appointing experts in CSR to spend the amount wisely and improve CSR disclosure to compete in the international market; stakeholders have to pressure the firm to provide more CSR disclosure and for policymakers this study study provides useful inputs to design legal framework on CSR.Originality/valueThe measurement of CSR disclosure using environmental, social and governance (ESG) score is novel in Indian context, even though the methodology is often used in literature.
Formal institutional uncertainty and equity sought on foreign market entry: does industry matter?
Authors: Ahmed Kashif , Bebenroth Ralf , Hennart Jean-François 
Published: May 2020

Purpose
This study aims to examine how the effect of host country formal institutional uncertainty on the percentage of equity sought in cross-border acquisitions (CBAs) is moderated by the host country industry (i.e. targets from the technology versus those from the non-technology industry).

Design/methodology/approach
This study is based upon the legitimacy perspective of institutional theory and uses Tobit regression analysis on a sample of 1,340 CBAs.

Findings
Results show that cross-border acquirers prefer a lower equity level for targets in institutionally less developed countries and that this negative effect of the host country institutional risk on the equity percentage sought is more pronounced for technology-based targets.

Research limitations/implications
Three major limitations of the study are as follows: The data were collected from only Japanese acquirers. The study measured formal institutional uncertainty by applying only secondary data. The study used the Bloomberg Industry Classification Systems, instead of the Standard Industry Classification that has been used widely in prior studies.

Practical implications
This study shows that the industry selected has a bearing on equity sought in CBAs. Investing in institutionally less developed countries is particularly challenging when the targets of acquisition are in the technology industry.

Originality/value
To the best of the authors’ knowledge, this is the first study that investigates the moderating effects of an industry on the relationship between host country formal institutional uncertainty and the percentage of equity sought in CBAs.
The roseoflavin producer Streptomyces davaonensis has a high catalytic capacity and specific genetic adaptations with regard to the biosynthesis of riboflavin
Authors: Kißling Lena , Schneider Carmen , Seibel Katharina , Dorjjugder Nasanjargal , Busche Tobias , Kalinowski Jörn , Mack Matthias 
Published: May 2020

SummaryThe bacterium Streptomyces davaonensis synthesizes the antibiotic roseoflavin in the stationary phase of growth. The starting point for roseoflavin biosynthesis is riboflavin (vitamin B2) and four enzymes (RibCF, RosB, RosA and RosC) are necessary to convert a vitamin (riboflavin) into a potent, broad‐spectrum antibiotic (roseoflavin). In S. davaonensis, seven enzymatic functions are required to synthesize the roseoflavin precursor riboflavin from the central building blocks GTP and ribulose 5‐phosphate. When compared with other bacterial and in particular Streptomyces genomes the S. davaonensis genome contains an unusual high number (21) of putative riboflavin biosynthetic genes (rib genes), including a rib gene encoding an additional riboflavin synthase originating from an Archaeon. We show by complementation analyses and enzyme assays that 17 out of these 21 putative rib genes indeed encode for riboflavin biosynthetic enzymes. Biochemical analyses of selected enzymes support this finding. Transcriptome analyses show that all of the rib genes are expressed either in the exponential or in the stationary phase of growth and thus do not represent silent genes. We conclude that the Rib enzymes produced in the stationary phase represent a physiological adaptation to support roseoflavin biosynthesis.
Subclinical keratoconus detection with three‐dimensional (3‐D) morphogeometric and volumetric analysis
Authors: Toprak Ibrahim , Cavas Francisco , Velázquez José S. , Alio del Barrio Jorge L. , Alio Jorge L. 
Published: May 2020

AbstractPurposeTo assess the efficacy of morphogeometric and volumetric characterization of the cornea based on three‐dimensional (3‐D) modelling in diagnosis of subclinical keratoconus (KC).MethodsCross‐sectional study. Ninety‐three eyes with subclinical KC with a best spectacle‐corrected distance visual acuity ≥20/20 (grade zero KC according to the RETICS classification) and 109 control eyes were included. Computer‐based 3‐D corneal morphogeometric model was generated using raw topographic data. Distance‐, area‐ and volume‐based parameters were used for statistical analysis. Distance parameters included deviation of anterior (Dapexant)/posterior (Dapexpost) apices and minimum thickness points (Dmctant, Dmctpost) from corneal vertex, and Dapexant‐Dapexpost difference. Areal variables were derived from anterior (Aant) and posterior (Apost) corneal surfaces, sagittal plane passing through corneal apices (Aapexant, Aapexpost) and thinnest point (Amctant, Amctpost). Total corneal volume (Vtotal) and volumetric distribution (with 0.1mm steps) centred to thinnest corneal point (VOLmct) and anterior (VOLaap)/posterior (VOLpap) apices comprised the volume‐based parameters.ResultsIn the subclinical KC group, all D values, Dapexant‐Dapexpost difference, Aant, Apost and Aapexant values were higher (p < 0.001), while Aapexpost, Amctpost, Vtotal, VOLmct, VOLaap and VOLpap values were lower when compared to the control group (p < 0.001). Regression analysis‐based formula correctly classified 96.8% of the eyes with subclinical KC and 94.5% of the normal ones (p < 0.0001).ConclusionsEyes with subclinical KC seem to represent asymmetrically displaced anterior and posterior corneal apex, corneal thinning and volume loss. 3‐D morphogeometric and volumetric parameters and differentiation formula can be incorporated into topography software to detect subclinical KC with high sensitivity and specificity in clinical practice.
Venular oxygen saturation is increased in young patients with type 1 diabetes and mild nonproliferative diabetic retinopathy
Authors: C.B.B. Veiby Nina , Simeunovic Aida , Heier Martin , Brunborg Cathrine , Saddique Naila , Moe Morten C. , Dahl‐Jørgensen Knut , Margeirsdottir Hanna D. , Petrovski Goran 
Published: May 2020

AbstractPurposeTo clarify how early in the development of diabetic retinopathy (DR) can oxygen (O2) saturation changes be detected.MethodsRetinal oximetry was performed in a cross‐sectional study, involving 14‐ to 30‐year‐old individuals: 185 with type 1 diabetes (T1D) and 94 controls. The subjects were divided into four groups according to the grade of DR. One‐way ANOVA and post hoc tests were used to test for differences in the mean O2 saturations between the groups.ResultsFifty‐eight (31 %) of the T1D patients had nonproliferative DR. There was no significant difference in O2 saturations between controls and T1D patients with no DR. Arteriolar and venular O2 saturations in T1D patients were significantly higher in moderate/severe DR than in no DR (p = 0.009 and p > 0.001), while venular O2 saturation was significantly higher in mild DR than in no DR (p = 0.013).ConclusionIncrease in venular O2 saturation could not be detected before mild retinopathy had developed, and the retinal O2 saturation increase was measurable on the venular side first. Our results suggest that the increase in O2 saturation is likely a consequence of DR.
Bilateral pheochromocytoma: Clinical characteristics, treatment and longitudinal follow‐up
Authors: Kittah Nana Esi , Gruber Lucinda M. , Bancos Irina , Hamidi Oksana , Tamhane Shrikant , Iñiguez‐Ariza Nicole , Babovic‐Vuksanovic Dusica , Thompson Geoffrey B. , Lteif Aida , Young William F. , Erickson Dana 
Published: May 2020

AbstractObjectiveComprehensive data about patients with bilateral pheochromocytoma are limited. We aimed to describe the clinical presentation, genetic analysis, treatment and outcomes of patients with bilateral pheochromocytoma.DesignA retrospective study at a tertiary care centre.PatientsAll patients with bilateral pheochromocytoma evaluated at Mayo Clinic in Rochester, Minnesota between January 1951 and December 2015.MeasurementsTumour size, genetic testing, plasma/urine metanephrines and catecholamines.ResultsA total of 94 patients (51% women) were diagnosed with bilateral pheochromocytoma at a median age at first presentation of 31 years (range, 4‐70). Bilateral disease was noted in 8.0% of pheochromocytoma patient overall and 37.5% of patients 18 years of younger. Most patients presented with synchronous tumours (80%). Median time to metachronous tumours was 4.5 years (range, 1‐38). Genetic disease was identified in 75 (80%) patients, including MEN 2A (42.6%), VHL (19.1%), MEN 2B (9.6%) and NF1 (8.5%). Excess catecholamines were present in 97% of patients. Patients with synchronous pheochromocytoma commonly underwent simultaneous bilateral adrenalectomy (99%), and 18 (24%) had cortical‐sparing surgery. Multicentric tumours were reported in 23 of 77 (30%) patients with available data. Recurrent disease was found in 9.6% of patients, and 8.5% developed metastatic disease. Median follow‐up was 8.5 years. At the study conclusion, 4 patients had died due to pheochromocytoma or adrenalectomy.ConclusionsBilateral pheochromocytoma occurred in 7.0% of adults with pheochromocytoma and 37.5% of paediatric patients. Genetic disease was identified in 80% of patients, predominantly MEN2A. Multicentric tumours were common, but most were still cured following adrenalectomy.
Ambulance dispatch calls attributable to influenza A and other common respiratory viruses in the Netherlands (2014‐2016)
Authors: Monge Susana , Duijster Janneke , Kommer Geert Jan , van de Kassteele Jan , Krafft Thomas , Engelen Paul , Valk Jens P. , de Waard Jan , de Nooij Jan , Riezebos‐Brilman Annelies , van der Hoek Wim , van Asten Liselotte 
Published: May 2020

AbstractBackgroundAmbulance dispatches could be useful for syndromic surveillance of severe respiratory infections. We evaluated whether ambulance dispatch calls of highest urgency reflect the circulation of influenza A virus, influenza B virus, respiratory syncytial virus (RSV), rhinovirus, adenovirus, coronavirus, parainfluenzavirus and human metapneumovirus (hMPV).MethodsWe analysed calls from four ambulance call centres serving 25% of the population in the Netherlands (2014‐2016). The chief symptom and urgency level is recorded during triage; we restricted our analysis to calls with the highest urgency and identified those compatible with a respiratory syndrome. We modelled the relation between respiratory syndrome calls (RSC) and respiratory virus trends using binomial regression with identity link function.ResultsWe included 211 739 calls, of which 15 385 (7.3%) were RSC. Proportion of RSC showed periodicity with winter peaks and smaller interseasonal increases. Overall, 15% of RSC were attributable to respiratory viruses (20% in out‐of‐office hour calls). There was large variation by age group: in <15 years, only RSV was associated and explained 11% of RSC; in 15‐64 years, only influenza A (explained 3% of RSC); and in ≥65 years adenovirus explained 9% of RSC, distributed throughout the year, and hMPV (4%) and influenza A (1%) mainly during the winter peaks. Additionally, rhinovirus was associated with total RSC.ConclusionHigh urgency ambulance dispatches reflect the burden of different respiratory viruses and might be useful to monitor the respiratory season overall. Influenza plays a smaller role than other viruses: RSV is important in children while adenovirus and hMPV are the biggest contributors to emergency calls in the elderly.
Evaluation of a mobile health approach to improve the Early Warning System of influenza surveillance in Cameroon
Authors: Monamele Chavely Gwladys , Messanga Essengue Loique Landry , Ripa Njankouo Mohamadou , Munshili Njifon Hermann Landry , Tchatchueng Jules , Tejiokem Mathurin Cyrille , Njouom Richard 
Published: May 2020

AbstractBackgroundRapid reporting of surveillance data is essential to better inform national prevention and control strategies.ObjectivesWe compare the newly implemented smartphone‐based system to the former paper‐based and short message service (SMS) for collecting influenza epidemiological data in Cameroon.MethodsOf the 13 sites which collect data from persons with influenza‐like illness (ILI), six sites send data through the EWS, while seven sites make use of the paper‐based system and SMS. We used four criteria for the comparison of the data collection tools: completeness, timeliness, conformity and cost.ResultsRegarding the different collection tools, data sent by the EWS were significantly more complete (97.6% vs 81.6% vs 44.8%), prompt (74.4% vs n/a vs 60.7%) and of better quality (93.7% vs 76.1% vs 84.0%) than data sent by the paper‐based system and SMS, respectively. The average cost of sending a datum by a sentinel site per week was higher for the forms (5.0 USD) than for the EWS (0.9 USD) and SMS (0.1 USD). The number of outpatient visits and subsequently all surveillance data decreased across the years 2017‐2019 together with the influenza positivity rate from 30.7% to 28.3%. Contrarily, the proportion of influenza‐associated ILI to outpatient load was highest in the year 2019 (0.37 per 100 persons vs 0.28 and 0.26 in the other 2 years).ConclusionAll sentinel sites and even other disease surveillance systems are expected to use this tool in the near term future due to its satisfactory performance and cost.
A five‐microRNA signature for individualized prognosis evaluation and radiotherapy guidance in patients with diffuse lower‐grade glioma
Authors: Zhang Jian‐Hua , Hou Ruiqin , Pan Yuhualei , Gao Yuhan , Yang Ying , Tian Wenqin , Zhu Yan‐Bing 
Published: May 2020

AbstractDespite the prognostic value of IDH and other gene mutations found in diffuse glioma, markers that judge individual prognosis of patients with diffuse lower‐grade glioma (LGG) are still lacking. This study aims to develop an expression‐based microRNA signature to provide survival and radiotherapeutic response prediction for LGG patients. MicroRNA expression profiles and relevant clinical information of LGG patients were downloaded from The Cancer Genome Atlas (TCGA; the training group) and the Chinese Glioma Genome Atlas (CGGA; the test group). Cox regression analysis, random survival forests‐variable hunting (RSFVH) screening and receiver operating characteristic (ROC) were used to identify the prognostic microRNA signature. ROC and TimeROC curves were plotted to compare the predictive ability of IDH mutation and the signature. Stratification analysis was conducted in patients with radiotherapy information. Gene ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed to explore the biological function of the signature. We identified a five‐microRNA signature that can classify patients into low‐risk or high‐risk group with significantly different survival in the training and test datasets (P < 0.001). The five‐microRNA signature was proved to be superior to IDH mutation in survival prediction (AUCtraining = 0.688 vs 0.607). Stratification analysis found the signature could further divide patients after radiotherapy into two risk groups. GO and KEGG analyses revealed that microRNAs from the prognostic signature were mainly enriched in cancer‐associated pathways. The newly discovered five‐microRNA signature could predict survival and radiotherapeutic response of LGG patients based on individual microRNA expression.