bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of dietary diversity among adults on antiretroviral therapy in Debre Tabor Hospital, northwest Ethiopia: A cross-sectional study
Authors: Zerihun Kassaw Wubnew , Muhammad Esmael Ali , Biks Gashaw Andargie , Belew Aysheshim Kassahun , Hunegnaw Melkamu Tamir 
Published: January 2020

Abstract
Background: Diversified diet to improve better tolerates human immunodeficiency virus drugs, enhance antiretroviral therapy adherence and maintain a healthy weight to reduce mortality and morbidity. Therefore, the aim of this study was to assess dietary diversity and associated factors among adult human immunodeficiency virus positive patients who were on antiretroviral therapy at Debre Tabor Hospital northwest EthiopiaMethods: Institutional based cross-sectional study was conducted at Debre Tabor Hospital and participants selected by the systematic random sampling techniques. Data collection was done by using a structured interview questionnaire. Dietary diversity was computed from all food and drink list consumed in the 24 hours preceding the survey. A variable having p- value < 0.2 in the bivariate logistic regression was entered into the multivariable logistic regression, and independent variables having p-value < 0.05 was considered as significantly associated. Results: Of the total 341 adults on antiretroviral therapy 336 participants gave a complete response with a response rate of 98.50%. Among the participants 336 [32.4% (95% CI: 27.4, 37.1)] had adequate dietary diversity and 22.9% were BMI <18.5kg/m2. Government employment [AOR= 2.5; 95%CI: 1.28, 4.98) and diploma and above educational status [AOR=2.3; 95% CI: 1.01, 5.31) were factors for adequate dietary diversity. Conclusions: In this study the magnitude of adequate dietary diversity was low. Employment and educational status were significantly associated with dietary diversity among people living with HIV/AIDS. Hence, improving education status as well as income generation activities are highly recommended strategy to improve the dietary diversity of patients on antiretroviral therapy.
Understanding Women’s Perspectives on Breast Cancer is essential for cancer control: Knowledge, Risk Awareness, and Care-seeking in Mwanza, Tanzania
Authors: Chao Christina A. , Huang Liuye , Visvanathan Kala , Mwakatobe Kisa , Masalu Nestory , Rositch Anne 
Published: January 2020

Abstract
Background: Breast Cancer is the most common cancer in women worldwide. Since 2008, Mwanza, Tanzania, has worked to provide comprehensive cancer services through its Zonal consultant hospitals. A new policy focused on clinical breast exam requires that women be aware of and seek care for breast concerns. This new policy necessitates the understanding of community women’s perspectives on breast cancer and care-seeking behavior which are key to successful cancer control.Methods: A community-based survey was administered to conveniently sampled women aged 30 and older to assess women’s perspectives on breast cancer and care-seeking behavior.Results: Among 1,129 women with a median age of 37 (IQR: 31-44) years, 73% have heard of cancer and 10% have received breast health education. Women self-evaluated their knowledge of breast cancer (from 1-none to 10-extremely knowledgeable) with a median response of 3 (IQR: 1-4). Only 14% felt they knew any signs or symptoms of breast cancer. Encouragingly, 56% of women were fairly-to-very confident they would notice changes in their breasts, with 24% of women practicing self-breast examination and 21% reporting they had received a past breast exam. Overall, 74% said they would be somewhat-to-very likely to seek care if they noticed breast changes, with 96% noting severity of symptoms as a motivator. However, fear of losing a breast (40%) and fear of a poor diagnosis (38%) were most frequent barriers to care seeking. In assessing knowledge of risk factors, about 50% of women did not know any risk factors for breast cancer whereas 42% of women believed long term contraceptive use a risk factor. However, 37% and 35% of women did not think that family history or being older were risk factors, respectively.Conclusions: The success of efforts to improve early diagnosis in a setting without population-based screening depends on women being aware of breast cancer signs and symptoms, risks, and ultimately seeking care for breast concerns. Fortunately, most women said they would seek care if they noticed a change in their breasts, but the low levels of cancer knowledge, symptoms, and common risk factors highlight the need for targeted community education and awareness campaigns.
Metabolic Syndrome and Risk of Colorectal Cancer: Results of Propensity Score-based Analyses in a Community-based Cohort Study
Authors: Kim Jinsun , Park Eun Young , Park Eunjung , Lim Min Kyung , Oh Jin-Kyoung , Kim Byungmi 
Published: January 2020

Abstract
Background: This study aimed to determine the effects of metabolic syndrome (MetS) on colorectal cancer (CRC) using propensity score (PS) methods.Methods: The study subjects were 2,417 men and 4,568 women from the Korean National Cancer Center (KNCC) Community Cohort between 2003 and 2010 who were followed up by 2016. We calculated adjusted hazard risks (HRs) and 95% confidence intervals (CIs) using unadjusted and multiple Cox's hazard regression models, PS matching analysis, regression models adjusted by the PS or stratified into five strata according to PS, and PS weighting methods.Results: In women, MetS and abnormally high triglyceride (TG) levels were associated with an increased risk of CRC (HR for MetS, 2.11 [95% CI, 1.21-3.86] using the multiple Cox's hazard regression and 2.19 [95% CI, 1.10-4.36] using the PS matching analysis; HR for abnormal TG levels, 2.09 [95% CI, 1.21-3.62] using the multiple Cox's hazard regression and 2.10 [95% CI, 1.08-4.08] using the PS matching analysis). In men, MetS did not show a significant association with the risk of incident CRC no matter which analyses we performed (HR, 0.92 [95% CI, 0.42, 2.04] using the PS matching analysis).Conclusions: Our study might provide additional evidence that deteriorated metabolic profiles increase the risk of CRC in women rather than men. Thus, it may have an important role in effective population-level interventions for deteriorated metabolic profiles at an early stage.
Body Mass Index of children and adolescent participants in a voucher program designed to incentivise participation in sport and physical activity
Authors: Owen Katherine , Bellew B , Foley Bridget C , Bauman Adrian , Reece Lindsey J 
Published: January 2020

Abstract
Background There has been limited population-level success in tackling overweight and obesity. The Active Kids program is a state-wide intervention that aims to increase participation in organised physical activity and sport among children and adolescents in NSW, Australia. This study profiled children and adolescents who registered for the Active Kids program by examining the prevalence of overweight and obesity across subgroups and by social disadvantage in this sample. MethodsFor participating children, each parent or carer was required to complete an online registration form with information about the child’s height, weight, physical activity, sport participation, age, sex, primary language spoken at home, Aboriginality, disability status and postcode. Descriptive statistics were used to profile children and adolescents who registered in the program and multinomial regression models were used to determine which demographic characteristics were associated with an increased risk of overweight and obesity. Results In 2018, 671,375 parents registered a child or adolescent for the Active Kids Program. Among these children and adolescents, the prevalence of overweight and obesity was 17.2% and 7.6%, respectively. A large number of children and adolescents who lived in the most disadvantaged area (n = 99,583; 14.8%) registered for the program. There was a clear socio-economic gradient for obesity prevalence across areas of increasing disadvantage, with children and adolescents living in the most disadvantaged area being 1.87 (95% CIs 1.82, 1.93) times more likely to be overweight or obese compared with children and adolescents living in the least disadvantaged area. Conclusions The Active Kids program successfully reached a substantial proportion of overweight and obese children from socially disadvantaged backgrounds, providing financial support and opportunities for these children to participate in organised sport and physical activity. However, the program did not reach all children, and additional physical activity promotion strategies may be needed in a comprehensive approach. Nonetheless, these findings support government investment in reaching childhood overweight and obesity with large-scale programs.
TANA: efficient approach for predicting protein functions by transferring annotation via alignment networks
Authors: DJEDDI Warith Eddine , YAHIA Sadok BEN , NGUIFO Engelbert MEPHU 
Published: January 2020

Abstract
Background: One of the challenges of the post-genomic era is to provide accurate function annotations for orphan and unannotated protein sequences. With the recent availability of huge protein-protein interactions networks for many model species, the computational methods revealed a great requirement to elucidate protein function based on many strategies. In this respect, most computational approaches integrate diverse kinds of functional interactions to unveil protein functions by transferring annotations across different species by relying on similar sequence, structure 2D/3D, amino acid motifs or phylogenetic profiles. Results: In this work, we introduce a new approach called TANA for inferring protein functions. The main originality of the introduced approach stands on the function prediction for the unannotated protein by transferring annotation via a network alignment as well as from the direct interaction neighborhood within their PPI networks. Doing so, we are able to discover the functions of proteins that could not to be easily described by sequence homology. We assess the performance of our method using the standard metrics established by the CAFA and highlight a sharp significant improvement over other competitive methods, in particular for predicting molecular functions. Conclusions: This research is one of the first attempts that combine sequence and networks-multiple-alignment-based function prediction approaches. We have been able to assess the accuracy of the prediction using pairwise and multiple alignment of the PPI networks for the compared species. Therefore, we recommend using different strategies (i.e pairwise, multiple, with/without neighborhood networks) especially in situations where the functions of the protein are not known in advance.
A modern view on the treatment of chronic hepatitis C in children and adolescents
Authors: Volynets G. V. 
Published: January 2020

The purposeof the article is a summary overview of approaches to the treatment of infection caused by hepatitis C virus (HCV) in children and adolescents. The article is devoted to issues affecting indications, contraindications and optimal treatment regimens in children and adolescents with chronic HCV infection.All over the world, 13.2 (11.5–21.2) million children aged 1–15 years have HCV. Chronic HCV infection in children, as a rule, is more lethargic than in adults; extrahepatic manifestations mainly in the form of subclinical hypothyroidism and autoimmune thyroiditis occur, respectively, in 11 and 5.6% of cases. The risk of developing liver cirrhosis in children with chronic HCV infection ranges from 1 to 4%, while bridging fibrosis and severe liver inflammation are described in approximately 15%. The article discusses the issues of therapy: goals, endpoints, indications, contraindications and the optimal treatment regimen in children with chronic HCV infection. The recommendations made by the European Society for Pediatric Gastroenterologists, Hepatologists and Nutritionists (ESPGHAN) are provided.Conclusion.Chronic HCV infection in children in general is in a benign form, but treatment of the disease is required to achieve success in eliminating hepatitis C.
Prevalence and time trends of neural tube defects in regions of the Russian Federation
Authors: Demikova N. S. , Podolnaya M. A. , Lapina A. S. 
Published: January 2020

Neural tube defects – a group of severe congenital malformations with a high level of mortality, childhood disability. The average prevalence of these defects is approximately 1 per 1000 births. The main measures to reduce the prevalence of neural tube defects are primary and secondary prevention measures, the effectiveness of which can be determined by congenital malformations monitoring.Research purpose. To determine the prevalence of neural tube defects, as well as trends in their prevalence for 2011 to 2017 in the Russian Federation according to monitoring of congenital malformations.Results. The total prevalence of anencephaly among newborns and fetuses was 4.63 (95% confidence interval - CI 4.40–4.88) per 10000 births, spina bifida – 6.18 (95% CI 5.91–6.46) and encephalocele 1.34 (95% CI 1.21–1.47). At the same time, the prevalence of anencephaly only among live births was 0.11 (95% CI 0.08–0.15) per 10000, spina bifida – 2.24 (95% CI 2.08–2.41) and encephalocele – 0 25 (95% CI 0.20–0.31). The decrease in prevalence of birth defects among live births compared with the total prevalence is provided by a high level of detection of these defects by ultrasound examination during pregnancy with the subsequent elimination of the affected fetuses. The maximum proportion of eliminated fetuses is observed for anencephaly (90.5%), for encephalocele the proportion of aborted fetuses is 77.4% and for spina bifida – 59.3%. Over the 7-year period, the multidirectional prevalence trends were noted: the increasing trend for total prevalence of neural tube defects and the decreasing trend for prevalence of these defects among live-born children.Conclusion. Estimates of the prevalence of neural tube defects in Russian Federation regions are obtained. The dynamics of the studied defects prevalence indicates that the decreasing of neural tube defects prevalence among live births is associated with secondary prevention measures.
Prognostic value of connective tissue dysplasia in children with urinary tract infection
Authors: Pleshkova E. M. , Dlin V. V. 
Published: January 2020

Research purpose. To determine the frequency and severity of connective tissue dysplasia in children with urinary tract infection to predict the course of the disease and justify the scope of the survey.Characteristics of children and research methods. A prospective study was conducted during 5 years, which included 120 children with community-acquired urinary tract infection at the age of 1 to 17 years. There were 90 children with acute pyelonephritis and 30 patients with acute cystitis. All children underwent a clinical and instrumental examination with a study of the manifestations of connective tissue dysplasia and assessment of its severity.Results. Connective tissue dysplasia occurred in 30% of children with urinary tract infection and depended on the form and course of pyelonephritis. With secondary pyelonephritis, its frequency increased to 56% with a predominance of the first degree of severity. When prospectively observed, only in 2 out of 30 girls with acute cystitis, the disease took a chronic course; one of them was diagnosed with connective tissue dysplasia of the I degree of severity. A relapse-free course of pyelonephritis was observed in 54 (68%) children. In 25 (32%) patients with secondary pyelonephritis, the course of the disease was recurring; in this group, connective tissue dysplasia was significantly more frequent and was observed in 23 (92%) of 25 patients.Conclusion. If seven to ten external signs of connective tissue dysplasia are detected in children with pyelonephritis, it is necessary to examine not only the urinary system, but also other systems for complex treatment.
Combining artificial aeration and biological zeolite mulch for nitrogen removal from eutrophic water bodies
Authors: Lu Cheng , Cheng Wen , Wang Min , Zhou Zhiwei 
Published: January 2020

Abstract
Endogenous nitrogen pollution can be a major cause of eutrophication. Nitrogen species release from sediments can be reduced by biologically-enforced zeolite mulch or water column aeration. This study was about their combined effects. Water and surface sediment samples from the Yangzhou ancient canal were aerated and biozeolite mulching was applied separately and in combination for 81 days, while the nitrogen species removal rate was recorded. The combination of aeration and biozeolite mulching removed &gt;95% of the ammoniacal-nitrogen in 15 days. This was better than either the blank control or biozeolite mulch without aeration. The ammoniacal-nitrogen concentration was lowered faster by combined treatment than by aeration alone. Nitrate nitrogen was only detected during aeration between days 10 and18, and reached lower concentration in the presence of biozeolite. Nitrate was formed during aeration but its concentrations were higher and more variable in the absence of biozeolite; that is, mulching stabilized nitrate formation. The total nitrogen concentration reached its lowest levels after 81 days with biozeolite treatment alone, with 78% total nitrogen removal, whereas combined aeration with biozeolite achieved 41%. This shows that biozeolite mulching can remove nitrogen in eutrophic waters, even without aeration.
Is het gebed een dialoog?
Authors: Dekker P.D. 
Published: January 2020

This article explores the nature of prayer: is prayer dialogue? If so, how does this relate to the experience of the petitioner? In conversation with John Calvin, Sarah Coakley and Gerrit Immink, this essay argues that prayer is a dialogue in which the petitioner and God maintain their subjectivity, but in asymmetrical and reciprocal ways. It is argued that the affirmation of God’s subjectivity in prayer affects both the doctrine ofGod and theological anthropology in numerous ways. The most important of these is a diminished emphasis on causality in the approach to God and therefore a less deterministic history than is often assumed in the Reformed tradition. It also affords a serious reconsideration of the influence of the petitioner through prayer in Christ’s reign.
Hubungan Beban Kerja dan Peran Ganda dengan Kelelahan Kerja Pengrajin Batik
Authors: Herdianti Herdianti , Maryana Tatik , Supriatna Supriatna 
Published: January 2020

<p><em>Latar belakang: Di Batik Mawar, hampir semua pekerjaan dikerjakan secara manual menggunakan tangan dan lengan atas secara berkesinambungan yang dikombinasi dengan ketelitian kerja dan penggunaan alat-alat tradisional. Pekerjaan mempunyai beban kerja yang berat dikarenakan semua proses kerja dilakukan oleh pengrajin yang sama sehingga menimbulkan kelelahan disamping itu pekerjanya juga memiliki peran ganda. Tujuan penelitian ini adalah untuk mengetahui hubungan beban kerja dan peran ganda dengan perasaan lelah pada pengrajin batik mawar. Metode: Penelitian ini merupakan penelitian Kuantitatif dengan desain penelitian Cross Sectional. Populasi dalam penelitian ini adalah semua pengrajin di Batik Mawar. Pengambilan sampel pada penelitian ini menggunakan teknik total sampling dengan jumlah sampel penelitian sebanyak 40 responden. Analisis data yang digunakan Univariat dan Bivariat. Hasil: Hasil analisis data yang menggunakan uji Chi-Square untuk beban kerja didapatkan nilai p-Value = 0,001. Hasil analisis data yang menggunakan uji Chi-square untuk peran ganda didapatkan nilai p-value= 0,031. Dengan demikian disimpulkan bahwa ada hubungan yang bermakna antara beban kerja dan peran ganda dengan perasaan lelah. Sebaiknya pengrajin mencuci pakaian 2 kali sehari, memasak makanan siap saji, selain itu dengan cara bersama-sama dalam menyelesaikan pekerjaan dirumah</em></p><p><em><br /></em></p><p><em><em>Background: In Batik Mawar, almost all work is done manually using the hands and upper arms on a continuous basis combined with the rigor of work and the use of traditional tools. The work has a heavy workload because all the work process is done by the same craftsman causing fatigue besides that the worker also have double role. The purpose of this study is to determine the relationship between workload and dual role with feelings of fatigue on craftsmen batik roses.Method: This research is Quantitative research with Cross Sectional research design. The population in this study are all artisans in Batik Mawar. Sampling in this study using total sampling technique with the number of research samples as many as 40 respondents. Data analysis used by Univariat and Bivariat.Result: Result of data analysis using Chi-Square test for work load got value p-Value = 0,001. The result of data analysis using Chi-square test for double role got p-value = 0,031. Thus, it is concluded that there is a meaningful relationship between workload and dual role with feeling tired. We recommend that craftsmen wash clothes 2 times a day, cook ready meals, other than that together in completing the work at home</em></em></p>
Hubungan Paparan Media Informasi Tentang Vaksin Palsu Dengan Minat Ibu Dalam Melakukan Imunisasi
Authors: Zurhayati Zurhayati , Maria Sihotang Hetty , Serlinika Gita 
Published: January 2020

<p><em>H</em><em>a</em><em>sil Survei World Health Organitation (WHO) terdapat 1,5 juta anak mengalami kematian tiap tahunnya, disebabkan oleh penyakit yang sebetulnya bisa dicegah dengan imunisasi. Dilain pihak rasa ketakutan kepada efek samping vaksinasi menjadi lebih dominan dibandingkan dengan ketakutan terhadap penyakitnya. Tujuan penelitian untuk mengetahui hubungan paparan media informasi tentang vaksin palsu dengan minat ibu dalam imunisasi di wilayah kerja Puskesmas Rawat Inap Simpang Tiga Pekanbaru tahun 2017. Penelitian ini merupakan penelitian analitik kuantitatif dengan desain cross sectional. Analisis data terdiri dari analisis univariat. Bivariat menggunakan uji chi square. Populasi penelitian seluruh </em><em>ibu yang memiliki bayi dan balita berusia 0-12 bulan</em><em> berjumlah 216. Sampel diambil dengan teknik Random Sampling, didapatlah 140 sampel. Hasil penelitian menunjukkan mayoritas terpapar media informasi sebanyak 98 (70.0%), dan minoritas tidak terpapar media informasi sebanyak 42 (30%). Hasil uji chi square nilai (P value = 0,000 &lt; 0,05. Ada hubungan paparan media informasi tentang vaksin palsu dengan minat ibu dalam melakukan imunisasi.</em></p><p> </p><p><em>The results of the World Health Organitation Survey (WHO) have 1.5 million children experiencing death each year, caused by diseases that can actually be prevented by immunization. On the other hand the fear of the side effects of vaccination becomes more dominant than the fear of the disease. The purpose of the study was to determine the relationship of exposure to information media about fake vaccines with the interest of mothers in immunization in the working area of the Inpatient Health Center of Simpang Tiga Pekanbaru in 2017. This study was a quantitative analytical study with a cross sectional design. Data analysis consisted of univariate analysis. Bivariate uses the chi square test. The study population of all mothers who have infants and toddlers aged 0-12 months amounted to 216. Samples were taken by Random Sampling technique, obtained 140 samples. The results showed that the majority of information media were exposed to 98 (70.0%), and 42 (30%) were not exposed to information media. The value of the chi square test (P value = 0,000 &lt;0,05). There is a relationship between exposure to media information about fake vaccines with the interest of mothers in immunization.</em><em></em></p>