bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiple attenuation methods in short-offset 2D marine seismic data: a case study in Cendrawasih Bay
Authors: Yuza N H , Nainggolan T B , Manik H M 
Published: January 2020

Abstract
Real marine seismic data are typically embedded with free-surface multiples energy, which are troublesome in imaging an accurate seismic cross-section. In addition, more challenging situation is to bring optimum result with a short-offset streamer due to the coherent nature of multiples. In this study, we present a comparison of three methods for attenuating free-surface multiples energy in short-offset 2D seismic data from Cendrawasih Bay. Multiple attenuation methods include F-K filter, Radon transform, and Surface Related Multiple Elimination (SRME) are processed until the final Pre-Stack Time Migration (PSTM) results. Predictive deconvolution is applied in order to suppress short period multiples prior to free-surface multiple attenuation method. Predictive deconvolution successfully identifies and removes the predictable wavelet of short period multiples. Radon transform shows poor result in short-offset seismic data even if it is combined with F-K filter method. Combination of both F-K filter and SRME are successfully attenuate free-surface multiples and should be considered as proper solution to increase signal to noise ratio.
GIS-based spatio-temporal analysis on Yellow Fin Tuna catch in Eastern Indian Ocean off Sumatera
Authors: Nurholis  , Gaol J L , Syah A F , Dewi A K 
Published: January 2020

Abstract
Spatio-temporal analysis of yellow fin tuna fishing activity could give us new perception and perspective on studying this fisheries resource exploration. This study was carried out in Eastern Indian Ocean off Sumatera. Fishing data were collected between 2014 until 2018 from the hand line fishermen’s daily logbooks accessed from Bungus fishing port. Data were organized into a database and structured on a geographical reference to allow GIS-Based analysis. We performed raster calculator analysis and spatial statistical analysis to understand spatiotemporal distribution behaviour and fishing activity also employed the generalized additive model to understand the habitat preferences. The result of GIS-based analysis shows the dynamics of catch, effort and catch per unit effort distribution patterns, underlining the annual differences of geographical distribution and fishing pattern. The most concentrated fishing activity monitored in 2014 while the more dispersed fishing activity monitored in 2017. The geographic orientation of spatial distribution monitored at range between 72.90 degrees until 176.15 degrees. GIS provide an important and powerful tool to analyse fishing information to help decision makers in the EIO off Sumatera on Tuna management.
Double Vision: Adaptation, the Uncanny andInvasion of the Body Snatchers
Authors: Hodgkins John 
Published: January 2020

AbstractThis essay takes a renewed look at the 1978 film Invasion of the Body Snatchers, directed by Philip Kaufman, along with its source texts: Jack Finney’s 1954 novel The Body Snatchers and Don Siegel’s 1956 adaptation. Specifically, I use the uncanny as a conceptual lens for thinking about my own reaction to Kaufman’s movie, and what I argue is the film’s reaction to its literary and cinematic precursors. In the process, I try to demonstrate how the uncanny might prove a useful critical tool for theorizing adaptive works, especially those in the horror genre.
Range-wide neutral and adaptive genetic structure of an endemic herb from Amazonian Savannas
Authors: Silva Amanda R , Resende-Moreira Luciana C , Carvalho Carolina S , Lanes Eder C M , Ortiz-Vera Mabel P , Viana Pedro L , Jaffé Rodolfo 
Published: January 2020

AbstractConserving genetic diversity in rare and narrowly distributed endemic species is essential to maintain their evolutionary potential and minimize extinction risk under future environmental change. In this study we assess neutral and adaptive genetic structure and genetic diversity in Brasilianthus carajensis (Melastomataceae), an endemic herb from Amazonian Savannas. Using RAD sequencing we identified a total of 9365 SNPs in 150 individuals collected across the species’ entire distribution range. Relying on assumption-free genetic clustering methods and environmental association tests we then compared neutral with adaptive genetic structure. We found three neutral and six adaptive genetic clusters, which could be considered management units (MU) and adaptive units (AU), respectively. Pairwise genetic differentiation (FST) ranged between 0.024 and 0.048, and even though effective population sizes were below 100, no significant inbreeding was found in any inferred cluster. Nearly 10 % of all analysed sequences contained loci associated with temperature and precipitation, from which only 25 sequences contained annotated proteins, with some of them being very relevant for physiological processes in plants. Our findings provide a detailed insight into genetic diversity, neutral and adaptive genetic structure in a rare endemic herb, which can help guide conservation and management actions to avoid the loss of unique genetic variation.
Publication Bias and Editorial Statement on Negative Findings
Authors: Blanco-Perez Cristina , Brodeur Abel 
Published: January 2020

AbstractIn February 2015, the editors of eight health economics journals sent out an editorial statement which aimed to reduce the extent of specification searching and reminds referees to accept studies that: ‘have potential scientific and publication merit regardless of whether such studies’ empirical findings do or do not reject null hypotheses’. Guided by a pre-analysis, we test whether the editorial statement decreased the extent of publication bias. Our differences-in-differences estimates suggest that the statement decreased the proportion of tests rejecting the null hypothesis by 18 percentage points. Our findings suggest that incentives may be aligned to promote more transparent research.
Bilateral giant inguinoscrotal hernia. Presentation of a novel combined two-stage repair approach
Authors: Menenakos Charalambos , Albrecht Hendrik C , Gretschel Stephan 
Published: January 2020

Abstract
Giant inguinoscrotal hernia is typically defined as hernia extending below the midpoint of the inner thigh, in the standing position. These hernias can be a demanding surgical problem as replacing bowel contents into the abdomen that can cause a life-threatening increase in intra-abdominal pressures. Various techniques such as preoperative progressive pneumoperitoneum (PPP), debulking of abdominal contents with visceral resections with or without omentectomy and phrenectomy have been suggested. We report the case of a 65-year-old patient with giant bilateral inguinal hernia. We applied a novel two-stage combined approach consisting of PPP with simultaneous single shot injection of botulinum toxin Type A into the anterior abdominal wall, and a second stage laparotomy with hernia repair (Stoppa technique). This technique makes possible the successful treatment of giant inguinal hernias without the need for visceral resection. To our knowledge, this is the first presented case of this combined treatment modality.
Functional Movement Screen Items Predict Dynamic Balance Under Military Torso Load
Authors: Scudamore Eric M , Stevens Sandra L , Fuller Dana K , Coons John M , Morgan Don W 
Published: January 2020

AbstractIntroductionMusculoskeletal injuries threaten military readiness and impose a significant financial burden. The functional movement screen (FMS), a 7-item, preparticipation screening tool, may aid in identifying compensatory movement patterns that can hinder physical performance and lead to injuries in active-duty military personnel. The primary aim of our study was to determine if items scores from the traditional FMS or a modified FMS (mFMS) obtained under loaded conditions can predict dynamic balance scores while wearing a military load.Materials and MethodsThirty physically active adults (19 males and 11 females) who qualified for Army basic training completed unloaded and loaded FMS testing. Loaded balance was assessed using the Y balance test and the Biodex balance system. The mFMS and both loaded balance assessment protocols included a military load consisting of a standard issue rucksack (M.O.L.L.E.), kevlar helmet, and weighted vest (mass = 24.2 kg).ResultsmFMS item scores were significantly lower than FMS scores for six of the seven movement items. Both FMS and mFMS composite scores were correlated with Y balance scores (FMS: r = 0.53, P = 0.003; mFMS: r = 0.37, P = 0.043). Participants with higher composite scores (≥15) outperformed those with lower composite scores (≤14) for the FMS (P =0.006, d = 1.16) and mFMS (P = 0.031, d = 0.75). Lasso penalized regression analyses revealed that (1) higher unloaded in-line lunge subscores predicted better Y balance scores, (2) loaded trunk stability push-up scores of three predicted worse balance on the Biodex, and (3) unloaded and loaded shoulder mobility scores of 3 predicted better performance on the Biodex balance system.ConclusionsThe in-line lunge subscore from the FMS was the strongest predictor of torso-loaded balance, and the FMS may be more appropriate than a torso-loaded FMS battery when predicting torso-loaded balance among adults with body composition and fitness profiles similar to those of entering military recruits. These findings provide evidence supporting the use of the conventional FMS to identify active-duty personnel who exhibit greater balance deficits and may develop related musculoskeletal injuries while performing operational tasks that require the transport of heavy loads over long distances.
Practicing Military Medicine in Truly Austere Environments: What to Expect, How to Prepare, When to Improvise
Authors: Anagnostou Evangelos , Michas Athanasios , Giannou Christos 
Published: January 2020

AbstractIntroductionThe majority of the published literature on contemporary military medicine contradicts the concept of austere. Operational medicine is part of every armed conflict around the world, while armed forces of most countries internationally have limited medical resources especially in the front line. The aim of this review is to identify the particularities of a truly austere environment and present a short guide of preparation and action for military medical personnel internationally.Materials and MethodsAn exhaustive search of the existing English literature on operational and military medicine in austere environments was carried out in EMBASE and PubMed databases.ResultsThis review included seminal and contemporary papers on the subject and synthesized a multiperspective short guide for operational medical personnel.DiscussionExperience from forward surgical teams of the U.S. Army and humanitarian teams of physicians in war zones who work under precarious and austere circumstances has shown that the management of casualties requires different strategies than in higher levels of combat casualty care and in a civilian setting. A number of factors that must be controlled can be categorized into human, environmental, equipment-related, and socioeconomic. Surgeons and other medical personnel should have knowledge of these aspects beforehand and be adequately trained in peacetime. Physicians must master a number of essential skills and drugs, and be familiar with dosage regimens and side effects.ConclusionThe military surgeon must be specially trained and prepared to use a wide range of skills in truly austere environments in contemporary conflicts.
Conflict-of-laws rules on assignments of receivables in the United States and Canada
Authors: Deschamps Michel 
Published: January 2020

Abstract
This article describes the conflict-of-laws rules of the USA and Canada on the effectiveness against third parties and priority of an assignment of trade receivables. Comparisons are also made with the rules proposed on these issues by the European Commission’s Proposal of 12 March 2018 and the UNCITRAL Model Law on Secured Transactions. The conflict-of-laws rules examined in the article generally designate the location of the assignor as the place whose law applies to the effectiveness against third parties and the priority of an assignment.
The article shows however that the definition of the location of the assignor varies from one jurisdiction to another (statutory seat, chief executive office, state of constitution, etc.) Moreover, the US rules and certain Canadian rules define the location of a business corporation using a criterion which is different depending on the corporation’s jurisdiction of incorporation. In addition, the European Commission’s Proposal allows the parties to an assignment made in the course of a securisation transaction to deviate from the assignor’s location rule and select the law governing the receivable as the applicable law. All of these differences result in a lack of harmonization.
The article also summarizes the analysis that a financier must conduct to identify the jurisdiction(s) where the financier would normally want that an assignment in its favour be recognized. The relevant jurisdictions are normally the jurisdiction(s) in which insolvency proceedings relating to the assignor may take place and the other jurisdiction(s) where the debtors of the receivables could be located; a dispute might sometimes occur in these other jurisdictions with a competing claimant attempting to claim priority (e.g. a judgement creditor who would seize receivables owed by the debtors located in those jurisdictions). As the insolvency jurisdiction(s) and the other jurisdiction(s) in which the debtors are located may have different conflict-of-laws rules, a prudent financier should examine the applicable rules of all relevant jurisdictions.
Observed Progression of Parents' Understanding of Preterm Infants' Behavioral Signs at 33 to 35 Weeks Corrected Age
Authors: Nakai Aya , Nakamura Nobue 
Published: January 2020

Background:
Interventions aimed at improving parental understanding of preterm infants' behavioral signs have drawn increased attention in recent years. However, there are limited data regarding parents' actual perceptions of infants' behavior during parent–infant interactions while infants are in a light-sleep state.

Purposes:
(1) To describe parental perceptions of infants' behavior at 33 to 35 weeks' corrected age during light-sleep and (2) to identify changes in parental perceptions of preterm infants' behavior over time.

Methods:
This study used a qualitative, longitudinal design based on observations and interviews. Three sets of parents and their infants born between 29 and 30 weeks' gestational age were observed up to 3 times during light sleep states when the infants were 33 to 35 weeks' corrected age. Parents were interviewed regarding their perceptions of infant behavior/growth once at the time of observation and once more within 2 weeks of the final observation. The findings are based on the observation of parents' perception-driven interactions with infants.

Results:
Four themes emerged describing the transition of parental perception that progresses to gain a better understanding of their infant's behavior through repeated interaction.

Implications for Practice:
The findings of this study inform caregivers in neonatal intensive care units regarding the unique experience of parent–infant dyads. This knowledge can help promote family-centered developmental care efforts in neonatal intensive care units.

Implications for Research:
Further research should focus on studying a larger sample group to confirm the findings and refining strategies to incorporate the findings to enhance neonatal intensive care unit care.
Metabolic Responses to Metformin in Inoperable Early-stage Non–Small Cell Lung Cancer Treated With Stereotactic Radiotherapy
Authors: Chun Stephen G. , Liao Zhongxing , Jeter Melenda D. , Chang Joe Y. , Lin Steven H. , Komaki Ritsuko U. , Guerrero Thomas M. , Mayo Ray C. , Korah Bobby M. , Koshy Suja M. , Heymach John V. , Koong Albert C. , Skinner Heath D. 
Published: January 2020

Background:
Metformin reduces glucose uptake in physiologic tissues and has been shown to affect non–small cell lung cancer (NSCLC) metabolism. We hypothesized that positron emission tomography (PET) scans could detect the impact of metformin on glucose uptake in NSCLC and we sought to test this hypothesis in a prospective clinical trial.

Materials and Methods:
A single-blinded phase II clinical trial was performed with subjects randomized 6:1 to 3 to 4 weeks of metformin versus placebo for inoperable early-stage NSCLC. PET scans were performed at baseline, mid-treatment (after 2 wk study medication), and 6 months postradiation. The primary endpoint of the trial was tumor metabolic response to metformin by PERCIST before definitive radiation. Stereotactic body radiotherapy to 50 Gy in 4 fractions was used for peripheral tumors and 70 Gy in 10 fractions for central tumors.

Results:
There were 14 subjects randomized to the metformin and 1 to placebo. Histologies were 60% adenocarcinoma, 33.3% squamous cell carcinoma, and 6.7% poorly differentiated carcinoma. At mid-treatment PET scan, 57% of subjects randomized to metformin met PERCIST criteria for metabolic response, of which 75% had progressive metabolic disease and 25% had partial metabolic response, whereas the placebo subject had stable metabolic disease. At 6 months, the metformin arm had 69% complete metabolic response, 23% partial metabolic response and 1 progressive metabolic disease, and the subject treated with placebo had a complete metabolic response. There were no CTCAE grade ≥3 toxicities.

Conclusions:
Despite low accrual, majority of subjects treated with metformin had metabolic responses by PERCIST criteria on PET imaging. Contrary to the effect of metformin on most physiologic tissues, most tumors had increased metabolic activity in response to metformin.
Recent Health Care Expenditure Trends Among Adult Cancer Survivors in United States, 2009-2016
Authors: Rubens Muni , Ramamoorthy Venkataraghavan , Saxena Anshul , Das Sankalp , Bhatt Chintan , Veledar Emir , McGranaghan Peter , Sundil Subrina , Shehadeh Nancy , Viamonte-Ros Ana , Linhares Yuliya , Odia Yazmin , Chuong Michael , Kotecha Rupesh , Mehta Minesh P. 
Published: January 2020

Objective:
The objective of this study was to understand recent trends in direct health care expenditures among cancer survivors using novel cost-estimation methods and a nationally representative database.

Materials and Methods:
This study was a retrospective analysis of 193,003 adults, ≥18 years of age, using the Medical Expenditure Panel Survey during the years 2009-2016. Manning and Mullahy two-part model was used to calculate adjusted mean and incremental medical expenditures after adjusting for covariates.

Results:
The mean direct annual health care expenditure among cancer survivors ($13,025.0 [$12,572.0 to $13,478.0]) was nearly 3 times greater than noncancer participants ($4689.3 [$4589.2 to $4789.3]) and were mainly spent on inpatient services, office-based visits, and prescription medications. Cancer survivors had an additional health care expenditure of $4407.6 ($3877.6, $4937.6) per person per year, compared with noncancer participants after adjusting for covariates (P<0.001). The total mean annual direct health care expenditure for cancer survivors increased from $12,960.0 (95% confidence interval: $12,291.0-$13,628.0) in 2009-2010 to $13,807.0 ($12,828.0 to $14,787.0) in 2015-2016.

Conclusions:
Given the higher health care expenditures among cancer survivors and the increasing prevalence of cancers, cost-saving measures should be planned through multidisciplinary initiatives, collaborative research, and importantly, health care planning and policy changes. Our findings could be helpful in streamlining health care resources and interventions, developing national health care coverage policies, and possibly considering radically new insurance strategies for cancer survivors.
Geographic variations and potential macro-environmental exposure of hypertension: from the China hypertension survey
Authors: Pei Lijun , Wu Jilei , Wang Zengwu , Wang Xin , Chen Zuo , Li Jiajia , Zhang Linfeng , Fan Rujing , Zhang Zugui , Dong Ying , Zheng Congyi , Kang Yuting , Gao Runlin 
Published: January 2020

Objectives:
The study aimed to investigate the spatial variation of hypertension (HTN) and the associations between the risk of HTN and altitude, longitude, latitude in Chinese population.

Methods:
The newest China Hypertension Survey (CHS) study, which used a nationally representative sample, was conducted between 2012 and 2015. A total of 451 755 participants aged at least 18 years from 262 county-level regions in 31 provinces were analyzed to explore the geographical variations of HTN prevalence at county-level. A total of 444 375 participants were included in two-level logistic regression model to examine the association between HTN risk and exposure to altitude, longitude, and latitude after adjusting for potential confounding variables at individual level.

Results:
The findings of spatial analysis indicated that there were remarkably high and low HTN prevalence zones. High HTN prevalence zones extended from parts of the southeast to northern China and the northeast. The risk of HTN increased with increasing longitude, with adjusted odds ratios (aORs, 95% confidence interval [CI]) of 2.08 (1.04--4.18), 2.21 (1.15--4.22), 2.54 (1.31--4.93), 2.59 (1.32--5.08), and 2.81 (1.12--7.08) for longitudes of 90–100°E, 100–110°E, 110–120°E, 120–130°E, and at least 130°E, respectively, with a significant dose--response relationship that HTN risks increase as longitude rises from 90°E to ≥130°E(P
trend <0.001), compared with the longitude group of less than 80°E, consistent with the conclusion that geographical variations of high HTN prevalence zones by spatial analysis.

Conclusion:
The findings of remarkably high HTN prevalence zones modified previous understandings about the regional difference of HTN distribution, and provide an important basis for future efforts to prevent and control HTN in different regions of China.
The Use of Sirolimus for Treatment of Orbital Lymphatic Malformations: A Systematic Review
Authors: Shoji Marissa K. , Shishido Sachie , Freitag Suzanne K. 
Published: January 2020

Purpose:
Orbital lymphatic malformations are rare congenital choristomas associated with pain, proptosis, exposure keratopathy, and vision loss. Current treatments of surgery, drainage, and sclerotherapy may have adverse effects including risk of damage to surrounding structures, swelling, and malformation persistence or recrudescence. Sirolimus, which inhibits mammalian target of rapamycin, a regulator of cell growth and vascular endothelial growth factor expression, has successfully treated systemic vascular malformations. However, its efficacy and safety have not yet been well established for orbital lymphatic malformations.

Methods:
Systematic review and analysis of relevant published literature were performed. PubMed, Embase, and World of Science searches were conducted for studies involving sirolimus treatment of orbital lymphatic malformations through July 2019.

Results:
Nine case series and reports with 10 total patients who received sirolimus for treatment of orbital lymphatic malformations were included. The age at sirolimus initiation ranged from 1 week to 23 years. The malformation was lymphatic in 6 patients, lymphaticovenous in 3 patients, and lymphatic-arteriovenous in 1 patient. Six patients underwent ineffective prior therapy including sclerotherapy, surgery, or medical therapy. Initial sirolimus dosage ranged from 0.05 mg/kg twice a day to 1 mg twice a day, and duration ranged from 6 months to 53 months. Seven patients had partial response, and 3 patients, all of whom had a microcystic malformation component, experienced complete response. Adverse effects included mild reversible leukopenia, hypertriglyceridemia, hypercholesterolemia, and transaminitis with adverse effects denied or not specified for 6 patients.

Conclusions:
Sirolimus may be a safe and effective treatment for orbital lymphatic malformations, especially microcystic malformations.