bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre- and Postoperation Risk Factors for Hirschsprung-associated Enterocolitis in Vietnamese Children
Authors: Viet Hoang Tran , Minh Tuan Huynh , Truong Nhan Vu , Phuong Anh Huynh Thi , Bich Uyen Nguyen , The Hao Chung , Uy Linh Truong Nguyen 
Published: December 2024

Abstract

Hirschsprung-associated enterocolitis (HAEC) can occur before and after surgery, increasing the complication rates, hospital stay, and treatment costs.
Objective: This study aims to determine the incidence of preoperative and postoperative Hirschsprung-associated enterocolitis HAEC and the related risk factors.
Methods: A prospective cohort study was conducted at two children's hospitals in Ho Chi Minh City, Vietnam of Hirschsprung's disease patients under 16 years of age from December 2022 to June 2024. The postoperative follow-up is 12 months.
Results: We enrolled 84 pediatric patients, with a male-to-female ratio of 5.4/1 and an average age of 7.2 ± 1.07 months. Of these, 25% of the patients had preoperative enterocolitis at admission, and 34.5% had at least one episode of preoperative enterocolitis. Postoperative enterocolitis occurred in 14 patients (16.7%), at an average post-operative 4.03 months. Chi-squared and OR analysis revealed that risk factors for preoperative enterocolitis at admission included a history of enterocolitis (OR=3.53; p=0.024), low weight in hospital (p=0.001), and lack of preoperative treatment (p=0.01). Multiple logistic regression of postoperative enterocolitis was associated with a history of preoperative enterocolitis (OR=9.74; p<0.001), anastomotic stricture (OR=2.33; p=0.002), and the length of the aganglionic segment (p<0.05). No statistically significant association was found between the surgical method and the risk of postoperative enterocolitis.
Conclusion: A history of pre-operative enterocolitis, low weight, and anastomotic stricture are significant risk factors for postoperative enterocolitis in patients with Hirschsprung's disease. Therefore, preoperative medical treatment should be used if the patients have not yet undergone a definitive surgical procedure. This approach is suitable as the patients live far from medical centers in Vietnam.
Effects of acute pro-inflammatory stimulation and 25-hydroxycholesterol on hippocampal plasticity &amp; learning involve NLRP3 inflammasome and cellular stress responses
Authors: Izumi Yukitoshi , O'Dell Kazuko A. , Mennerick Steven , Zorumski Charles 
Published: December 2024

Abstract

Neuroinflammation is an increasingly important target for therapeutics in neuropsychiatry and contributes to cognitive dysfunction, disability and death across a range of illnesses. We previously found that acute effects of pro-inflammatory stimulation with lipopolysaccharide (LPS) on hippocampal long-term potentiation (LTP), a form of synaptic plasticity involved in learning and memory, requires synthesis of the oxysterol, 25-hydroxycholesterol (25HC) and exogenous 25HC mimics effects of LPS. However, downstream mechanisms engaged by LPS and 25HC remain uncertain. Here we use rat hippocampal slices and in vivo behavioral studies to provide evidence that acute modulation of synaptic plasticity by both LPS and 25HC requires activation of the NLRP3 inflammasome, caspase-1 and interleukin-1 receptor. Furthermore, both LPS and 25HC engage cellular stress responses including synthesis of 5a-reduced neurosteroids and effects on plasticity are prevented by modulators of these responses. In studies of acute learning using a one-trial inhibitory avoidance task, inhibition of learning by LPS and 25HC are prevented by pre-treatment with an inhibitor of NLRP3. The present studies provide strong support for the role of 25HC as a mediator of pro-inflammatory stimulation on hippocampal synaptic plasticity and for the importance of NLRP3 inflammasome and caspase-1 activation in the deleterious effects of acute inflammation.
Parameter Estimation of a 2D Mathematical Model for Multi-Stage Compound Channels
Authors: Jamali Abdolreza , Aminnejad Babak , Zahiri Abdolreza 
Published: December 2024

Abstract

While a significant body of research has been focused on classic compound channels, few studies have focused on the multi-stage compound channels. Multi-stage compound channels have more than one floodplain on each side of the main channel. In these channels, when the flood occurs and the main channel is filled, the first floodplain is activated, and then when this floodplain overflows, the second floodplain immediately participates. In this study, three parameters of the two-dimensional model of Shiono and Knight (SKM) are estimated for multi-stage compound channels. Through calibration process, it was found that the effect of eddy viscosity and secondary currents in these channels is significant and should be considered. The calibrated SKM showed a good agreement between the observed and calculated lateral velocity and also bed shear stress distributions, total flow discharges as well as the zonal flow rates. Mean and maximum errors in estimating the total flow discharges were 4.1 and 9.7 percents, respectively. These errors for main channel’s flow discharges estimation were obtained as 4.9 and 10.6 percents, respectively. Meanwhile, the vertical divided channel method, widely used in water engineering packages, with an average error of 23% and a maximum error of 32% does not provide reliable results for total flow discharges. Results showed that SKM can estimate the total and the subdivision flow discharges in multi-stage compound channels with reasonable accuracy.
Differential gene expression during pupal development of Lucilia sericata (Diptera: Calliphoridae) for improving postmortem interval estimation
Authors: Pereira Ana Julia , Sonzogni Silvina , Centeno Nestor , Guiñazu Natalia 
Published: December 2024

Abstract

The main objective of forensic entomology is to estimate the postmortem interval (PMI) by analyzing the size and duration of the immature stages of insects colonizing a cadaver. However, this estimation becomes difficult during the pupal stage due to the absence of significant visible morphological changes. This study explores the differential gene expression of Lucilia sericata (Calliphoridae) pupae as a molecular tool for PMI estimation. Pupae were collected daily under controlled conditions at 23°C, and RNA was extracted for transcriptomic analysis. Six target genes (ecdysone receptor, Hsp90, actin, regucalcin, wingless, and fat body protein 1) were identified and correlated with distinct percentages of pupal development. Our results suggests that the combination of the expression levels of at least three genes, such as ecdysone receptor, regucalcin, and wingless, is sufficient to infer the percentage of pupal development throughout the entire pupal stage. Additionally, graphical tools were developed to facilitate the use of individual and grouped genes as markers for L. sericata age estimation. Since the pupal period comprises approximately half of the Calliphoridae developmental cycle, these findings are particularly valuable when pupae represent the most advanced evidence recovered from a crime scene or autopsy.
Runoff prediction using combined machine learning models and signal decomposition
Authors: Zhang Xiaoli , Wang Ruoyu , Wang Wenchuan , Zheng Qimeng , Ma Rui , Tang Rong , Wang Yuntao 
Published: December 2024

ABSTRACT

Accurate forecasting of increasingly unpredictable river runoff is essential for effective water resource management in the face of climate change and human activities. This study uses four machine learning models of long short-term memory neural networks (LSTM), support vector machine (SVM), random forest, and artificial neural network models to improve runoff forecasting accuracy and explore combined forecasting models’ effectiveness. This study develops three advanced combined forecasting models (empirical mode decomposition (EMD)–LSTM, VMD–LSTM, wavelet analysis (WA)–LSTM) by combining preprocessing techniques of EMD, variational mode decomposition (VMD), and WA with the LSTM modeling method. These models use signal decomposition techniques to analyze 41 years of runoff data from the Huanren station (1980–2020). The findings reveal that the LSTM model outperforms the other three individual machine learning models when forecasting days with high runoff. Among the three decomposed combined models, the VMD–LSTM model demonstrates the best overall performance during the validation period, achieving root mean square error, Nash–Sutcliffe efficiency coefficient, and bias values of 52.14 m3/s, 0.96, and −0.002, respectively. The combination of LSTM with signal decomposition techniques shows promising potential for enhancing runoff prediction accuracy, with practical implications for water resource management and flood control strategies.
Effects of magnetotactic bacteria (MTB) on membrane fouling control in an ultrafiltration treatment of chromium-containing surface water
Authors: Lu Shuailiang , Liu Guicai , Dou Yingjie , Zhang Zhengzhou , Zhou Zhiyong , Xie Kang 
Published: December 2024

ABSTRACT

Ultrafiltration membranes are widely used in the treatment of surface water. However, membrane fouling is a core issue that needs to be addressed in its application. Magnetotactic bacteria (MTB) show early film-forming and magnetotactic behaviour in the presence of external magnetic fields. The objective of this study was to alleviate membrane fouling in ultrafiltration membranes using MTB, which can prioritise film formation and show directional movement under external magnetic fields. The concentration of Cr6+ in the water was 10 mg/L, and the dosage of MTB was 10 mg/L. Results show that the transmembrane pressure of the ultrafiltration membrane decreased by 5 kPa following the application of a magnetic field of 33.71 mT for a period of 90 min, and the membrane fouling could therefore be effectively controlled. With the addition of MTB, the average removal of Cr6+ from water by the ultrafiltration system was 20.10%, which was 14.56% higher than that of the conventional ultrafiltration system. The average removal of chromaticity was 20.13%, which was 10% higher than that achieved by the conventional ultrafiltration system. Furthermore, MTB progressively developed into the predominant flora during the operational phase, thereby enhancing the efficiency of the ultrafiltration system.
ANALISIS PENGARUH PEMBIAYAAN KREDIT PERBANKAN, LAMA USAHA, DAN MEDIA PEMASARAN DIGITAL TERHADAP KEBERLANGSUNGAN USAHA MIKRO (STUDI KASUS USAHA MAKANAN DAN MINUMAN DI KOTA MALANG)
Authors: Evita Safitri  , Farah Wulandari Pangestuty  
Published: December 2024

This research aims to analyze the influence of banking loan financing , business age, and digital marketing media on micro-sized enterprises income in Malang City. This research uses quantitative research methods with linear regression analysis. The data used in this research uses primary data in the form of a questionnaire distributed to 99 respondents who are micro-sized enterprises in Malang City. This research found that the results of banking loan financing had a significant positive effect on the income of Food and Beverage enterprises in Malang City, Business age had no significant effect on the income of food and Beverage enterprises in Malang City, and Digital marketing had a significant positive effect on the income of Food and Beverage enterprises in Malang City.
The Correlation of Snack Consumption and Physical Activity Between Nutritional Status in University Students
Authors: Aliya Donna Nathania , Pratama Satwika Arya 
Published: December 2024

The nutritional status of adolescents is a problem that requires special attention because it has a significant impact on their growth and physical development as adults. Possible nutritional problems that can occur in students include malnutrition, anemia (iron deficiency), obesity and other micronutrient deficiencies. This research uses quantitative research and a cross-sectional research design with the dependent variable, nutritional status. Meanwhile, the independent variables, namely snack consumption intake and physical activity, were analyzed univariately and bivariately using the Pearson test. The results of this study show that the relationship between consumption of energy, protein, fat and carbohydrate snacks is not related to nutritional status with a value of p0.05. Meanwhile, the results of the relationship between physical activity were not related to nutritional status with a p value of 0.05. Students at the Faculty of Engineering, Surabaya State University are advised to control the food they consume by choosing nutritious food and doing regular physical activity such as exercising and taking a leisurely walk.
STUDI TENTANG SELF-TALK POSITIVE DAN NEGATIVE ATHLETE: TINJAUAN DAN AGENDA MASA DEPAN DENGAN MENGGUNAKAN BIBLIOMETRIC ANALYSIS
Authors: Farhah Irsyad , Muluk Hamdi , Kurniawan Wawan 
Published: December 2024

Abstract Self-talk is a commonly used mental training strategy among athletes to manage emotions, enhance motivation, and improve performance in sports. Self-talk can be either positive or negative, with each type having different impacts on athletic performance. This study aims to explore various research on positive and negative self-talk in sports through a bibliometric analysis using data from Scopus. The analysis is conducted to understand publication trends, identify productive authors and journals, and examine emerging themes in this field. By utilizing VOSviewer and RStudio, this study is expected to provide a comprehensive overview of the development of self-talk literature in sports and offer insights for future research directions.Abstrak Self-talk merupakan salah satu strategi pelatihan mental yang sering digunakan atlet untuk mengelola emosi, meningkatkan motivasi, dan memperbaiki performa dalam olahraga. Self-talk dapat bersifat positif maupun negatif, dengan masing-masing jenis memiliki dampak yang berbeda terhadap performa atlet. Penelitian ini akan mengeksplorasi berbagai penelitian tentang self-talk positif dan negatif dalam konteks olahraga melalui analisis bibliometrik menggunakan data dari Scopus. Analisis dilakukan untuk memahami tren publikasi, identifikasi penulis dan jurnal yang produktif, serta tema-tema yang berkembang di bidang ini. Dengan menggunakan VOSviewer dan RStudio, penelitian ini diharapkan dapat memberikan gambaran yang komprehensif mengenai perkembangan literatur self-talk dalam konteks olahraga dan menawarkan wawasan untuk arah penelitian selanjutnya.
Using a Consumer Wearable Activity Monitoring Device to Study Physical Activity and Sleep Among Adolescents in Project Viva: Cohort Study
Authors: Zhang Yutong , Bornkamp Nicole , Hivert Marie-France , Oken Emily , James Peter 
Published: December 2024

Abstract

Background
The increasing prevalence of physical inactivity and insufficient sleep in adolescents likely contribute to worsening cardiometabolic and mental health. However, obtaining accurate behavioral measures is a challenge. Consumer wearable devices offer a user-friendly method to assess physical activity and sleep.

Objective
This study aimed to describe the process and the preliminary results of physical activity and sleep collected using a consumer wearable Fitbit device in an adolescent cohort.

Methods
We provided Fitbit Charge 2 or Charge 3 wrist-worn activity monitors to adolescent participants in Project Viva, a Boston, Massachusetts area cohort, from 2017 to 2022. We invited participants to wear the devices for ≥7 days for 24 hours a day to measure their physical activity, heart rate, and sleep, and allowed them to keep the device as a participation incentive.

Results
We collected over 7 million minutes of physical activity, heart rate, and sleep data from 677 participants, female. The mean (SD) age of participants was 17.7 (0.7) years. Among the 677 participants, were non-Hispanic White, non-Hispanic Black, were Hispanic, non-Hispanic Asian, and belonged to other races. Participants demonstrated a high adherence to the research protocol, with the mean (SD) wear duration of 7.5 (1.1) days, and 90% of participants (612/677) had 5 or more days wearing the device for >600 minutes/day. The mean (SD) number of steps was 8883 (3455) steps/day and the mean (SD) awake sedentary time was 564 (138) minutes/day. Male participants were more often engaged in very active (27 minutes/day) and moderately active physical activity (29 minutes/day) compared with female participants (15 and 17 minutes/day, respectively). Over 87% (588/677) of participants had sleep data available for 5 or more days, among whom the average nightly sleep duration was 7.9 (SD 0.9) hours.

Conclusions
This study demonstrated the feasibility of using consumer wearable devices to measure physical activity and sleep in a cohort of US adolescents. The high compliance rates provide valuable insights into adolescent behavior patterns and their influence on chronic disease development and mental health outcomes.
Exploring the Needs and Preferences of Users and Parents to Design a Mobile App to Deliver Mental Health Peer Support to Adolescents With Type 1 Diabetes: Qualitative Study
Authors: Yakubu Titilola I , Jhajj Poonamdeep , Pawer Samantha , West Nicholas C , Amed Shazhan , Tang Tricia S , Görges Matthias 
Published: December 2024

Background
Beyond physical health, managing type 1 diabetes (T1D) also encompasses a psychological component, including diabetes distress, that is, the worries, fears, and frustrations associated with meeting self-care demands over the lifetime. While digital health solutions have been increasingly used to address emotional health in diabetes, these technologies may not uniformly meet the unique concerns and technological savvy across all age groups.

Objective
This study aimed to explore the mental health needs of adolescents with T1D, determine their preferred modalities for app-based mental health support, and identify desirable design features for peer-delivered mental health support modeled on an app designed for adults with T1D.

Methods
A semistructured qualitative focus group study was conducted with adolescents with T1D and parents of adolescents with T1D. Data were collected through pre–focus group surveys, including sociodemographic background, diabetes status, health care experiences, and focus group sessions, including their opinions on peer support and technology. A thematic analysis following an inductive and iterative process was performed to develop themes and subthemes from the collected information.

Results
Focus group participants included 10 adolescents (mean 16, SD 1 years; 8/10, 80% female; who had been living with diabetes for an average of 9, SD 5 years) and 10 parents (mean age 51, SD 7 years; 9/10, 90% female). Four core themes emerged: (1) experience: navigating adolescence with T1D, (2) empowerment: support systems that enabled better management of their T1D, (3) obstacles: societal barriers that affect adolescents’ T1D management, and (4) innovation: adolescent-driven preferences for digital peer support platforms.

Conclusions
App-based peer support offers a promising avenue for addressing the mental health needs of adolescents with T1D. Understanding the unique support needs of these adolescents and using this information to suggest design considerations for a mental health peer support app is an important step toward addressing their complex emotional and social challenges.
RESISTENCIAS ANDINAS Y BUEN VIVIR FRENTE AL EXTRACTIVISMO MINERO DURANTE LAS ÚLTIMAS DÉCADAS, UNA PERSPECTIVA DECOLONIAL: EL CASO DE QUIMSACOCHA-LOMA LARGA EN ECUADOR Y CONGA EN PERÚ
Authors: ALVIRA BRIÑEZ YAMILE 
Published: December 2024

Durante las últimas décadas en América Latina, la adopción del neoliberalismo, y el posneoliberalismo en la región andina sudamericana, favoreció las condiciones para que países como Perú y Ecuador se convirtieran en objeto de imposición e incremento significativo de megaproyectos de despojo basados en la extracción de minerales e hidrocarburos, entre otros bienes naturales y comunes, fomentados y avalados por organismos financieros internacionales, los gobiernos de países y las empresas transnacionales, bajo el argumento de promover el desarrollo y el progreso para estos. Sin embargo, estos megaproyectos afectan cada vez más la autonomía y los derechos de las comunidades campesinas e indígenas sobre sus territorios, poniendo en riesgo la existencia de sus diversas formas: modos de ser, sentir, pensar y reproducir la vida.
En esta investigación, resulta de interés académico, político y psicosocial el estudio y comprensión de las resistencias andinas y las prácticas colectivas con potencial político-transformador orientadas hacia un Otro vivir/Buen vivir, protagonizadas por comunidades campesinas, pueblos originarios y nacionalidades indígenas en la región andina, a partir de sus propios conocimientos, sabidurías y subjetividades, ante la imposición y expansión global de megaproyectos que implican el despojo y la destrucción de los territorios a través de la explotación y mercantilización de los bienes naturales, de importancia sociocultural y económica para la supervivencia de las comunidades que se ven directamente afectadas por este tipo de conflictos.
El campo de estudio se delimitó mediante un continuo ejercicio de indaga-acción, problematización y previa revisión documental, que originó interrogantes en relación con: 1. El contexto histórico, político y social del despojo en la modalidad del extractivismo minero en la región andina; 2. La resistencia indígena y campesina ante este despojo; y 3. Las prácticas colectivas con potencial político transformador hacia un Otro Vivir/Buen Vivir. Sin embargo, esta investigación, responde a la pregunta de: ¿Cómo emergen diversas formas/modos, sentidos y significados de resistencias campesinas e indígenas frente al despojo y la destrucción de la Vida bajo la modalidad del extractivismo minero y cómo se configuran prácticas y propuestas con potencial político transformador orientadas hacia un Otro Vivir/Buen Vivir a partir de los casos estudiados y acompañados?
How to perform a transtracheal aspirate in horses for diagnosis of lower respiratory tract disease
Authors: Bishop Rebecca C. , Nobrega Ana D. , Mersich Ina , Wilkins Pamela A. 
Published: December 2024

Abstract

OBJECTIVE
To describe indications for and demonstrate the technique to perform a transtracheal aspirate in horses. Transtracheal aspirate is indicated to collect samples for cytology and bacteriologic culture in cases of suspected pneumonia or other lower respiratory tract disease.

ANIMALS
1 healthy university-owned horse was used for demonstration purposes. Images of clinical case samples from the University of Illinois Veterinary Teaching Hospital are shown.

METHODS
The horse is restrained and sedated with detomidine or xylazine to facilitate restraint and butorphanol to minimize coughing. The ventral neck is clipped and aseptically prepared. The site of planned puncture proximal to the bifurcation of the sternocephalicus is anesthetized with lidocaine. Two to three 30-mL syringes are filled with saline aseptically. A stab incision is made with a No. 15 blade to the depth of the trachea. The trocar is advanced between tracheal rings on midline, the stylet removed, and the aspiration catheter advanced through the trocar to the level of the proximal horizontal trachea. Sterile saline (30 mL) is infused rapidly, and suction is applied to the syringe while slowly withdrawing the catheter until fluid is retrieved. The catheter and trocar are withdrawn and the puncture site covered with antimicrobial ointment or a light bandage.

RESULTS
Samples are collected in a plain tube for bacteriologic culture and EDTA for cytology. The visual appearance of purulent effluent confirms severe pneumonia.

CLINICAL RELEVANCE
Transtracheal aspirate is minimally invasive and simple to perform with available kits. Samples provide valuable information to guide treatment decisions and selection of antimicrobials for horses with suspected lower respiratory tract disease.