bluuebunny/crossref_metadata_2025_split huggingface dataset:
Old Dog, New Tricks: Influenza A Virus NS1 andIn VitroFibrillogenesis
Authors: Shaldzhyan A.A. , Zabrodskaya Y.A. , Baranovskaya I.L. , Sergeeva M.V. , Gorshkov A.N. , Savin I.I. , Shishlyannikov S.M. , Ramsay E.S. , Protasov A.V. , Kukhareva A.P. , Egorov V.V. 
Published: August 2020

ABSTRACTThe influenza NS1 protein is involved in suppression of the host immune response. Recently, there is growing evidence that prion-like protein aggregation plays an important role in cellular signaling and immune responses. In this work, we obtained a recombinant, influenza A NS1 protein and showed that it is able to form amyloid-like fibrilsin vitro. Using proteolysis and subsequent mass spectrometry, we showed that regions resistant to protease hydrolysis highly differ between the native NS1 form (NS1-N) and fibrillar form (NS1-F); this indicates that significant structural changes occur during fibril formation. The discovery of the ability of NS1 to form amyloid-like fibrils may be relevant to uncovering relationships between influenza A infection and modulation of the immune response.
Integrating genetics, morphology, and fungal host specificity in conservation studies of a vulnerable, selfing, mycoheterotrophic orchid
Authors: Fama Nicole M. , Sinn Brandon T. , Barrett Craig F. 
Published: August 2020

ABSTRACTMycoheterotrophic plants derive most or all carbon and nutrients from fungal partners and represent poorly understood components of forest biodiversity. Many are rare or endangered yet can be ecological indicators of forest ecosystem function due to their often highly specific fungal host requirements. One such species is the IUCN red-listed (‘vulnerable’), fully mycoheterotrophic orchid,Corallorhiza bentleyi. This recently described species is among the rarest plants in Appalachia, known from five counties in Virginia and West Virginia, USA. The species has a restricted range, small population size, and is self-pollinating. Here we take an integrative approach to conservation genetic assessment inC. bentleyiusing floral morphometrics, simple-sequence repeats, and fungal host DNA to characterize variation within and among sampling localities. Morphology reveals some differentiation among individuals from six sampling localities. Surprisingly, most genetic variation is found within localities, contra to the expectation for a selfing species. Fungal host DNA reveals extreme specificity upon a few genotypes of a single ectomycorrhizal host species,Tomentella fuscocinerea,across all localities. We discuss the conservation implications of morphological, genetic, and symbiotic diversity in this vulnerable species, and recommend additional assessment of conservation status based on: an obligate reproductive mode of selfing, preventing benefits of outcrossing among genetically non-identical individuals; extreme host specificity, severely restricting niche space; and highly fragmented habitat under threat from anthropogenic disturbance. This study underscores the importance of integrative conservation assessment, analyzing multiple data sources, and reveals patterns not readily apparent from census-based assessments alone.
Teaching strategies for linking knowledge acquisition and application in the architectural design studio
Authors: Saghafi Mahmoud Reza 
Published: August 2020

PurposeIn the context of architecture education, design studio projects usually start with “research” on the design theme and the context, but often there is no strong link between this research and its application in the project and the resultant design product. This paper explores strategies which link knowledge acquisition and knowledge application in design studio teaching and learning.Design/methodology/approachThese strategies have been applied in several design studios and master’s theses and involve sixteen years of research by the author through observation, surveys and analysis of student work.FindingsThe results show that these strategies are not limited to the design studio, with more than half of them (eight out of fourteen) also applicable in theoretical subjects that sit outside the design studio unit and generate knowledge of relevance to studio projects. As such, the paper advocates for a multi-level approach involving the following: course design and curriculum development, teaching and learning pedagogies and organizational decisions regarding the deployment of staff as for collaborative team-based teaching.Research limitations/implicationsThe results also recognize the relevance of problem-based and project-based learning to the broader higher education context and its dependence on a collaborative approach.Originality/valueThis paper which synthesizes this work contributes to the literature on architecture pedagogy, specifically that related to the integration of theoretical and practical subjects.
Exploring the moderated mediation relationship between leader narcissism and employees’ innovative behavior
Authors: Yang Jie , Chang Mingchao , Li Jian , Zhou Lulu , Tian Feng , Zhang JiangJiang 
Published: August 2020

PurposeBased on the social information processing theory, the purpose of this study is to propose a conceptualized moderated mediation model for testing the linkage between leader narcissism and employees’ innovative behavior through the mediating effect of employees’ cognitive dependency and the moderating effect of environmental uncertainty between employees’ cognitive dependency and their innovative behavior.Design/methodology/approachIn this study, multisource data from 266 employees and their supervisors in 11 large high-tech Chinese companies were collected through a field study and an online survey. The hypotheses were tested using structural equation modeling and bootstrapping.FindingsThe results of this study show that leader narcissism has a negative impact on employees’ innovative behavior and that employees’ cognitive dependency plays a mediating role between leader narcissism and employees’ innovative behavior. Cognitive dependency and environmental uncertainty play moderated mediation roles between leader narcissism and employees’ innovative behavior.Research limitations/implicationsIn the future, longitudinal research and experimental methods can be used to avoid common method bias. Further studies could allow leaders to evaluate environmental uncertainty and explore the emotional path by which leader narcissism has negative effects on followers’ innovation from social information processing theory. In addition, future studies can explore cognitive dependency more deeply from the perspectives of forced obedience and active worship.Practical implicationsOrganizations should warn leaders to control the dark side of narcissism and minimize environmental uncertainty to reduce barriers to innovation.Originality/valueThis study constructs the path of the effect of leader narcissism on employees’ innovation through employees’ cognitive dependency in a specific context, which enriches theoretical research on the link between leaders’ traits and employees’ innovative behavior. Along with the finding of leader narcissism’s negative effect on employees’ innovative behavior, this study explores the dark side of leader narcissism in the context of China’s high-tech firms and environmental uncertainty.
Dimensions of governance in interorganizational project networks
Authors: Kujala Jaakko , Aaltonen Kirsi , Gotcheva Nadezhda , Lahdenperä Pertti 
Published: August 2020

PurposeThe purpose of this study is to create a framework to analyze approaches for coordination, adaptation and safeguarding of exchanges in interorganizational project networks.Design/methodology/approachAn analysis framework to analyze governance in project networks was created based on a systematic review of existing literature. The framework was applied to analyze governance approaches used in a large infrastructure project implemented with an alliance project delivery method to illustrate the practical validity of the framework.FindingsThe analysis framework categorized governance in project networks in six dimensions: goal setting, rewarding, monitoring, roles and decision-making, coordination and capability building. A set of questions for each governance dimension was created and the analysis framework was applied in the context of a project alliance.Research limitations/implicationsThe focus of this research is on governance internal to a project network. The authors identified dimensions of governance in project networks and related governance approaches based on a systematic literature review. The practical applicability of the framework was validated in a single case study setting.Practical implicationsThe paper introduces a concept of governance in project networks, which takes the perspective that all actors that have an influence on project implementation are part of an interorganizational project network. The focal organization may have had a significant role in the design of governance, but governance also emerged from the network structure of companies and the interactions among them. The analysis framework created in this research can be used to design and analyze governance in different type of project context.Originality/valueThe paper introduces a concept of governance in project networks, which takes the perspective that all actors that have an influence on project implementation are part of an interorganizational project network.
Assessing project risks from a supply chain quality management (SCQM) perspective
Authors: Gaudenzi Barbara , Qazi Abroon 
Published: August 2020

PurposeProject-driven supply chain risks pose a significant threat to the success of complex development projects, in terms of achieving key performances such as quality, time and efficiency. The purpose of this paper is to adopt a supply chain quality perspective in order to explore and better understand the unique attributes of risks associated with project-driven supply chains for continuously improving the quality of both processes and products.Design/methodology/approachTheoretically grounded in the framework of Bayesian Belief Networks and Game theory, this paper develops a structured process for assessing and managing risks in project-driven supply chains. The application of the proposed approach is demonstrated through a simulation case study conducted on the development project of Boeing 787 aircraft.FindingsThe conflicting incentives amongst stakeholders in a supply chain can jeopardise the success of a project and therefore, assessment of this category of risks classified as “Game theoretic risks” needs special consideration. Project-driven supply chain risks pose a significant threat to the success of complex projects. The results of the study clearly revealed that without mitigating the game theoretic risks, the main objective of timely completion of the Boeing 787 project was not materialised. Further, the lack of management expertise was the major factor contributing to the overall project costs including cost of quality.Originality/valueThe proposed process and analyses present a significant and original insight in terms of capturing the key determinants of both product and service quality such as product performance, convenience and reliability of service, timeliness, ease of maintenance, flexibility, and customer satisfaction and comfort. Propositions are developed for ascertaining the significance of information sharing in a project-driven supply chain, and a fair sharing partnership is introduced to help supply chain managers in managing game theoretic risks in order to achieve the goals of quality, time and efficiency.
Destination central district: the representation of the conflict
Authors: Macías Rodríguez Damián , Del Espino Hidalgo Blanca , Pérez Cano María Teresa 
Published: August 2020

PurposeThe purpose of this paper is to represent the conflict of touristification in the central district of Seville to evaluate the dimension of the problem. Therefore, it focuses on the diagnostic representation of the conflict between citizens and tourists, to help define the coexistence of opposing interests and to bring solutions in favour of a liveable urban landscape.Design/methodology/approachThe research has implied a detailed analysis beyond the observation of data and statistics, which facilitated a complex diagnosis for decision-making. This has led to consider as an initial framework the main tourist resources, official agreements and civil manifestations regarding touristification. Then, factors of tourist density and one in-depth case study of changes in use have been mapped.FindingsFirst, an analysis of the urban spaces affected by the tourist dynamics following the degree of habitability of the resident citizens has been led. Second, of the conflict resulting from a relationship between economic activities, the attractiveness of the urban landscape and the tourist use of the space has been mapped.Originality/valueThrough the study of the central district of a city of great heritage value where conflicts begin to occur as a result of tourism, it is intended to contribute to the development of the spatial syntax of the tourist conflict, what could lead to improve responsible urban and social city policies.
Conceptualization of wasta and its main consequences on human resource management
Authors: Alsarhan Fadi , Valax Marc 
Published: August 2020

Purpose
This paper aims to offer a review of the concept of wasta, as a form of social capital in Arab societies. Furthermore, this paper seeks to elucidate the main implications of the use of wasta among human resource management (HRM) practices on the workplace environment and the overall performance of institutions.

Design/methodology/approach
The authors embraced a qualitative approach in this paper. A total of 27 semi-structured interviews were conducted with HR officials from different levels in a number of Jordanian public organizations.

Findings
The results obtained indicate that wasta has negative consequences on the overall performance of organizations, through the influence it exerts on employee motivation, morale and job satisfaction, frustration, workplace diversity, turnover, brain drain, as well as its effect on the image and reputation of the individuals and organizations alike.

Originality/value
In this paper, the authors attempted to illustrate the concept of wasta as a form of social capital and to analyze its links with the features of the Jordanian culture through two of Hofstede’s dimensions. Furthermore, this paper is based both on the available literature and on data obtained through the semi-structured interviews. The findings through this process not only corroborate what we already know in the literature but they also generate an understanding of the hidden mechanisms that link the different implications of wasta together, creating the actual known consequences of this practice.
A framework of hiring strategy for manpower hiring in a hyper-local food delivery organization
Authors: Das Debadyuti , Yadav Chirag 
Published: August 2020

PurposeThe present work attempts to determine an appropriate number of different categories of Delivery Persons for a Hyper-local Food Delivery Organization for different intervals within a day and across days within a week which would provide a satisfactory level of service to the target customers and at the same time would become cost-efficient.Design/methodology/approachCurrently the firm estimates the required number of Delivery Persons for “lunch peak” and “dinner peak” of the next week's weekdays and weekend based on the maximum number of orders occurring during the same period of both weekdays and weekend in the current week. The proposed approach involves determining the projected demand in every four-hourly interval of both week-days and weekend in the next week. Subsequently, the study has developed a simple integer programming model for determining the optimum number of Delivery Persons based on the projected demand data.FindingsThe existing approach followed by the firm indicates that the Delivery Persons remain unutilized during periods of low demand. The proposed model demonstrated savings to the tune of 21.4% in manpower cost without any erosion in the service level.Originality/valueThe study has made three tangible contributions. First, the development of a simple methodology for estimating the demand of next period allows the Managers to utilize dynamic demand data. Second, the development of a simple integer programming model helps managers determine an appropriate number of Delivery Persons in different intervals in both weekdays and weekend. Third, the development of a framework of hiring strategy aids managers in adopting a particular hiring strategy under a particular context keeping in mind the magnitude of demand for food, demand for delivery service and the cost of providing the service.
Money laundering with cryptocurrency: open doors and the regulatory dialectic
Authors: Dupuis Daniel , Gleason Kimberly 
Published: August 2020

Purpose
The purpose of this study is to describe the opportunities and limitations of cryptocurrencies as a tool for money laundering through six currently available “open doors” (exchange mechanisms). The authors link the regulatory dialectic paradigm to know your customer and anti-money laundering evasion techniques, highlight six tactics to launder funds with virtual assets and investigate potential law enforcement and regulatory alternates used to reduce the incidence of money laundering with digital coins.

Design/methodology/approach
The methodology used is the analysis of significant recent events and the availability of “fintech” crime-fighting tools and a literature review focusing on the application of the regulatory dialectic to innovations in existing crypto-asset markets that make them compelling to money launderers.

Findings
The authors examine the illicit use of cryptocurrency through Kane’s regulatory dialectic paradigm, identify a number of avenues for crypto to fiat exchange that are still available for those seeking to launder money using digital coins, review recently “closed doors” and make recommendations regarding the regulation of crypto-related markets that may assist in making them less desirable for potential criminals.

Research limitations/implications
The research is constrained by the state of the market for crypto to fiat exchange as of time of writing; the technology and products to launder money using these open doors is continually changing (as predicted by the regulatory dialectic).

Social implications
The regulatory dialectic predicts that regulatory response is reactive and often increasingly burdensome or oppressive. There is continuous innovation in the cryptocurrency market, which seeks to preserve privacy and anonymity with which regulators seek to keep up. From a social perspective, the response of bank regulators worldwide to existing open doors for crypto to fiat exchange used for money laundering may prove costly to individuals engaging in legitimate transactions, as well as financial criminals and may also erode the ability of individuals to maintain privacy regarding their financial information.

Originality/value
To the authors’ knowledge, there are yet no broad overview regarding the feasibility of money laundering across crypto-related assets within the paradigm of the regulatory dialectic.
Stakeholders’ categorization of the sustainable public procurement system: the case of Brazil
Authors: Oliveira Marcus Vinicius de Souza Silva , Simão João , Caeiro Sandra Sofia Ferreira da Silva 
Published: August 2020

PurposeEncouraged by the State, the Brazilian public organizations practice sustainable procurement as one of the strategies to promote sustainable development. Performing them requires understanding to manage stakeholders. The purpose of this study is to identify and categorize the stakeholders of Brazilian public organizations’ sustainable procurement system.5Design/methodology/approachPreliminarily, the stakeholders were identified in the literature and by interviews with experts. Later, in a multi-case study, it was categorized by the model of stakeholder salience.FindingsIn general, governmental and intra-organizational stakeholders were classified as more salient. However, some stakeholders considered important by literature and experts have been categorized as less salient by organizations.Originality/valueThe proposed categorization is useful for the system comprehension and will serve as a basis for the development of future works, notably those who propose to understand or evaluate the sustainable public procurement (SPP). Additionally, this work aims to enlarge the knowledge and the better practices of SPP in a large emerging South American country, giving its contribution to the transition to more sustainable societies.
CEO characteristics and bank performance: evidence from India
Authors: Gupta Neeraj , Mahakud Jitendra 
Published: August 2020

PurposeThe purpose of this study is to examine the impact of chief executive officer (CEO) personal characteristics on the performance of Indian commercial banks. Additionally, it also analyses the nonlinear relationship of CEO age and CEO tenure on the bank performance.Design/methodology/approachA balanced panel data approach has been used in this study. Particularly, the fixed effect estimation technique is used to examine the relationship between CEO characteristics and bank performance during the period 2009–2010 to 2016–2017.FindingsThe authors find that professional qualification of CEOs in finance stream enhances performance. Additionally, the impact of CEO duality is found to be positive and significant on performance. Male CEOs are beneficial for bank performance. Well experienced CEOs contribute to higher performance. The results are robust across the various proxies of bank performance, and sub-samples based on ownership, size of the bank and board size.Practical implicationsThis study provides insights to policy regulators and policymakers who are entrusted with the appointment of the CEOs in the banks in the light of the ongoing regulatory reforms.Originality/valueThis study can be considered as one of the early studies, which examines the association between CEO characteristics and bank performance from an emerging economy perspective. It also extends the existing study by considering both public and private banks operating in India.