bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safety Analysis of an Automobile Workshop Using Qualitative Risk Assessment Method and Risk Analysis Through the Structural Equation Modelling
Authors: Akintimehin Ayomide Olawale , Oke Sunday Ayoola 
Published: December 2019

Abstract
Automobile repair service hazards are risk factors for multiple severe accidents, and scientific proof reveals a relationship between repair activity hazards and accidents in the auto-mechanic workshop. In this research, the investigators approximated the impact of risk factors for automobile repair activities, using novel parameters, for severity of hazards and influences on subjects, and based on literature. Next, insights into the relationship between latent variables which are appraised by manifest variables using the structural equation modelling were pursued. The respondents answered questionnaires on probability of hazard occurrence, severity and some identified measured variables. The authors appraised 44 out of the 80 and 98 out of 99 distributed questionnaires for the first and second modules, respectively. The risk levels ranged between low and medium for the medium scale establishment due to the nature of work done in the automobile repair centre which exposes the workers to the level of risk. For the second module involving the use of structural equation modelling, the factor loading was the least for safety behaviours (0.06) and highest for machine efficiency (0.90). Of the fifteen hypotheses formulated six were accepted. It is concluded that the safety behaviour of workers depends safety on the workers in the firm irrespective of other factors such as management commitment to safety, environmental contributions and safety, communications. Understanding the impact of risk factors for automobile repair activities in workers is necessary in elevating awareness absent these parameters and to eliminate accidents.
A series of new layered lithium europium(II) oxoniobates(V) and -tantalates(V)
Authors: Funk Christian , Köhler Jürgen , Schleid Thomas 
Published: December 2019

AbstractThe new Ruddlesden-Popper-related phasesAn+1BnO3n+1(n = 3) with the compositions Li2Eu2Nb3O10, Li2Eu1.5Ta3O10, Li2EuKNb3O10, and Li2EuKTa3O10were synthesized by solid-state reactions from Li2[CO3] (+ K2[CO3]) and the corresponding refractory metals along with their oxides in a high-frequency furnace at temperatures aboveT = 1600°C. Their structures have been determined by single-crystal X-ray diffraction studies. Characteristic features are triple layers of corner-sharing [MO6]7−octahedra (M = Nb and Ta), which are connected via [LiO4]7−tetrahedra. The Eu2+cations are cuboctahedrally surrounded by 12 oxygen atoms and according to the Eu–O distances of around 275 pm, they have the oxidation state +2, as confirmed by XPS measurements. In the potassium-containing samples they share their positions with K+cations. The black compounds are stable in air at room temperature. Measurements of the magnetic susceptibilities in the range ofT = 5–300 K revealed Li2Eu2Nb3O10, Li2Eu1.5Ta3O10and Li2EuKTa3O10to be paramagnetic without any ordering.
Distribution of Midbrain Cholinergic Axons in the Thalamus
Authors: Huerta-Ocampo Icnelia , Hacioglu-Bay Husniye , Dautan Daniel , Mena-Segovia Juan 
Published: December 2019

AbstractCholinergic transmission is essential for adaptive behavior and has been suggested to play a central role in the modulation of brain states by means of the modulation of thalamic neurons. Midbrain cholinergic neurons from the pedunculopontine nucleus (PPN) and the laterodorsal tegmental nucleus (LDT) provide dense innervation of the thalamus, but a detailed connectivity mapping is missing. Using conditional tracing of midbrain cholinergic axons in the rat, together with a detailed segmentation of thalamic structures, we show that projections arising in PPN and LDT are topographically organized along the entire extent of the thalamus. PPN cholinergic neurons preferentially innervate thalamic relay structures, whereas LDT cholinergic neurons preferentially target thalamic limbic nuclei. Moreover, both PPN and LDT provide a dense innervation of the intralaminar thalamic nuclei. Notably, we observe a differential synaptic density that functionally dissociates between PPN and LDT innervation. Our results show that midbrain cholinergic neurons innervate virtually all thalamic structures and this innervation is functionally segregated.
Midkine-a Is Required for Cell Cycle Progression of Müller Glia during Neuronal Regeneration in the Vertebrate Retina
Authors: Nagashima Mikiko , D'Cruz Travis S. , Danku Antoinette E. , Hesse Doneen , Sifuentes Christopher , Raymond Pamela A. , Hitchcock Peter F. 
Published: December 2019

In the retina of zebrafish, Müller glia have the ability to reprogram into stem cells capable of regenerating all classes of retinal neurons and restoring visual function. Understanding the cellular and molecular mechanisms controlling the stem cell properties of Müller glia in zebrafish may provide cues to unlock the regenerative potential in the mammalian nervous system. Midkine is a cytokine/growth factor with multiple roles in neural development, tissue repair, and disease. Inmidkine-aloss-of-function mutants of both sexes, Müller glia initiate the appropriate reprogramming response to photoreceptor death by increasing expression of stem cell-associated genes, and entering the G1phase of the cell cycle. However, transition from G1to S phase is blocked in the absence of Midkine-a, resulting in significantly reduced proliferation and selective failure to regenerate cone photoreceptors. Failing to progress through the cell cycle, Müller glia undergo reactive gliosis, a pathological hallmark in the injured CNS of mammals. Finally, we determined that the Midkine-a receptor, anaplastic lymphoma kinase, is upstream of the HLH regulatory protein, Id2a, and of the retinoblastoma gene,p130, which regulates progression through the cell cycle. These results demonstrate that Midkine-a functions as a core component of the mechanisms that regulate proliferation of stem cells in the injured CNS.SIGNIFICANCE STATEMENTThe death of retinal neurons and photoreceptors is a leading cause of vision loss. Regenerating retinal neurons is a therapeutic goal. Zebrafish can regenerate retinal neurons from intrinsic stem cells, Müller glia, and are a powerful model to understand how stem cells might be used therapeutically. Midkine-a, an injury-induced growth factor/cytokine that is expressed by Müller glia following neuronal death, is required for Müller glia to progress through the cell cycle. The absence of Midkine-a suspends proliferation and neuronal regeneration. With cell cycle progression stalled, Müller glia undergo reactive gliosis, a pathological hallmark of the mammalian retina. This work provides a unique insight into mechanisms that control the cell cycle during neuronal regeneration.
A Multiple-Trait Bayesian Lasso for Genome-Enabled Analysis and Prediction of Complex Traits
Authors: Gianola Daniel , Fernando Rohan L 
Published: December 2019

AbstractA multiple-trait Bayesian LASSO (MBL) for genome-based analysis and prediction of quantitative traits is presented and applied to two real data sets. The data-generating model is a multivariate linear Bayesian regression on possibly a huge number of molecular markers, and with a Gaussian residual distribution posed. Each (one per marker) of the T×1 vectors of regression coefficients (T: number of traits) is assigned the same T−variate Laplace prior distribution, with a null mean vector and unknown scale matrix Σ. The multivariate prior reduces to that of the standard univariate Bayesian LASSO when T=1. The covariance matrix of the residual distribution is assigned a multivariate Jeffreys prior, and Σ is given an inverse-Wishart prior. The unknown quantities in the model are learned using a Markov chain Monte Carlo sampling scheme constructed using a scale-mixture of normal distributions representation. MBL is demonstrated in a bivariate context employing two publicly available data sets using a bivariate genomic best linear unbiased prediction model (GBLUP) for benchmarking results. The first data set is one where wheat grain yields in two different environments are treated as distinct traits. The second data set comes from genotyped Pinus trees, with each individual measured for two traits: rust bin and gall volume. In MBL, the bivariate marker effects are shrunk differentially, i.e., “short” vectors are more strongly shrunk toward the origin than in GBLUP; conversely, “long” vectors are shrunk less. A predictive comparison was carried out as well in wheat, where the comparators of MBL were bivariate GBLUP and bivariate Bayes Cπ—a variable selection procedure. A training-testing layout was used, with 100 random reconstructions of training and testing sets. For the wheat data, all methods produced similar predictions. In Pinus, MBL gave better predictions that either a Bayesian bivariate GBLUP or the single trait Bayesian LASSO. MBL has been implemented in the Julia language package JWAS, and is now available for the scientific community to explore with different traits, species, and environments. It is well known that there is no universally best prediction machine, and MBL represents a new resource in the armamentarium for genome-enabled analysis and prediction of complex traits.
O “apelo direto” está alterando o formato de comunicação dos partidos políticos: as redes sociais ganham espaço e reduzem as estruturas tradicionais de mediação
Authors: Biffignandi Fernando 
Published: December 2019

Realizada em seu gabinete na Universidade de Perugia, Itália, a entrevista com Paolo Mancini é um importante documento que nos instiga a pensar sobre um novo modelo de comunicação baseado na relação direta entre fonte e usuário, entre o político e o eleitor, um reflexo claro dos processos de transparência da informação. Mancini reforça que esta nova tendência de comunicação se aplica aos partidos políticos alterando algumas práticas tradicionais dentro das sociedades democráticas. Ao interagir diretamente com o eleitor, o político abre uma nova via comunicativa, um novo canal sem a intermediação tradicional. Mancini classifica este fenômeno como “apelo direto”, um estilo populista que permite ao político adaptar-se às ideias, linguagem e valores já compartilhados pelo cidadão. Para Mancini as administrações públicas são compelidas a publicar os dados, não apenas para cumprir a lei, mas porque indivíduos têm a possibilidade de acessar e fazer circular a informação através da rede.
Quantitative and qualitative estimation of Moroccan Trichoderma isolates capacity to solubilize rock phosphate
Authors: Kribel S. , Qostal S. , Ouazzani Touhami A. , Selmaoui K. , Mouria A. , Benkirane R. , Achbani El. H. , Douira A. 
Published: December 2019

Thirty Trichoderma isolates isolated from compost, various crops and soil with roots of adjacent sites to the phosphate mines of Morocco, were tested in vitro for their potential to solubilize phosphorus from phosphate rock. The qualitative assessment of phosphate solubilization by Trichoderma isolates was performed on Modified Pikovskaya Agar (MPA) solid medium. The visual observation of the 3- and 6-day-old cultures did not show any clear zone around the colony. However, all the isolates were able to grow on the culture medium 3 days after incubation, the maximum recorded diameter was 58.6 mm for isolate TR-B 98 (3) and the minimum value was 34.8 mm for isolate TS-EM-98 (2). After 6 days, they showed good radial growth that exceeded 79.8 mm with variable appearance of the mycelial density such as the isolates TS-B 98, TS-EM-98 (1) and TR-CB 2000 (1) that presented, respectively, high, regular and low mycelial density. Also, the Trichoderma isolates produced variable number of conidia on MPA medium. Quantitative estimation on the Modified Pikovskaya Broth (MPB) liquid medium showed a variable potential of the Trichoderma isolates to solubilize phosphate when the amount of soluble phosphorus remained low in the liquid medium without the fungus (0.26 mgL−1). The maximum concentration of soluble phosphorus was 11.92 mgL−1 with percentage of soluble phosphorus equal to 95.39% recorded by the isolate TR-TB 2000 after 9 days of incubation, followed by the isolates TR-B 98 (3), TS-B 98 and TR-EM 2 respectively, 11.20, 10.47 and 9.61 mgL−1 and 89.6, 83.76 and 76.38%. In addition, treatments with Trichoderma isolates provided a lower final broth pH which varied between 6.81 for TOL isolate and 3.40 for TS-B-2000 (2) compared to initial pH (7.2). The isolates that proved potent for phosphate solubilization displayed the highest fresh and dry weights such as TR-TB 2000 (FW = 4.11 g and DW = 2.56 g), while the lowest fresh and dry weight were noted in the weakest isolates for phosphate solubilization such as T27 (FW = 1.025 g and DW = 0.58 g).
The high solubilization potential of Trichoderma isolates can be exploited for the solubilization of fixed phosphorus present in the soil, thus improving soil fertility and plant growth.
The occurrence of grapevine rugose wood disease in Algeria
Authors: Bachir A. , Selmi I. , Lehad A. , Louanchi M. , Mahfoudhi N. 
Published: December 2019

Rugose wood disease constitutes one of the major grapevine disease complexes causing significant economic damage worldwide. It is widely distributed in all grapevine growing areas of the world and comprised of four individual syndromes, which may be caused by different viruses. These syndromes are Corky bark, LN 33 stem grooving, Kober stem grooving and Rupestris stem pitting (RSP). The present study focuses on the prevalence of three viruses associated with rugose wood complex (RWC) in Algeria.
Field inspections and collection of symptomatic samples were conducted on autumn 2012 in the table wine and autochthone accession in the western and central regions of Algeria. A total of 202 samples were tested by RT-PCR using specific primers for Grapevine virus A (GVA), Grapevine virus D (GVD) and Grapevine rupestris stem pitting associated virus (GRSPaV).
The results of RT-PCR indicated the presence of the viruses GVA, GVD and GRSPaV with 68,81% (139 out of 202 infected samples) total average infection rate. The results also indicated the predominance of GRSPaV compared to the prevalence of GVA and GVD with an infection rate of 57,92% vs. 36,63% (74 out of 202) and 2,97% (6 out of 202), respectively. Mixed infections of these three viruses were not observed in any of the samples analysed, however the mixed infection of GVA and GRSPaV was noted with a high rate of 26.73%. The grapevine cultivars; Kings Rubi, Carignan and Mersguerra were the most infected, while the Alicante Bouschet cultivar presented the lowest infection rate. To the best of our knowledge, the present study reports for the first time on the presence of GVD in Algeria.
Inhaled 5-methoxy-N,N-dimethyltryptamine: Supportive context associated with positive acute and enduring effects
Authors: Sepeda Nathan D. , Clifton John M. , Doyle Laura Y. , Lancelotta Rafael , Griffiths Roland R. , Davis Alan K. 
Published: December 2019

Background and aims 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a potent, short-acting psychedelic that produces strong hallucinogenic effects. The association between the context (i.e., set and setting) of 5-MeO-DMT use and the acute and enduring effects of the substance is unknown. Therefore, this study examined these associations using secondary data from two cross-sectional survey studies. Methods The acute and enduring effects of inhaled synthetic 5-MeO-DMT were compared between individuals who used 5-MeO-DMT in a non-structured context (NSC; n = 216, female = 10%, Mage = 35.5, SD = 11.8) and those who used in a structured context (SC; n = 362, female = 45%, Mage = 47.7, SD = 13.3). Questionnaires were administered online and responses were anonymized for privacy purposes. Respondents were asked to retrospectively rate their first experience with synthesized 5-MeO-DMT on measures of mystical experience, challenging experience, and enduring effects. Results Both groups endorsed high ratings on the Mystical Experience Questionnaire; however, mean scores were significantly higher in the SC group compared to the NSC group. Similarly, the proportion of respondents who had a complete mystical experience was significantly larger in the SC group (83%) compared to the NSC group (54%). Ratings of enduring effects (i.e., meaningfulness, spirituality, and well-being) were also significantly higher, and the intensity of challenging experiences was significantly lower, in the SC group compared to the NSC group. Conclusions 5-MeO-DMT appears to occasion mystical-type experiences with enduring positive effects, which are more intense when 5-MeO-DMT is administered in a safe and supportive context. Future prospective experimental studies should examine the effects of 5-MeO-DMT and its interactive relationship with supportive contextual factors.
Politecnia e Ensino Médio Integrado: aproximações e distanciamentos
Authors: Curi Luciano Marcos , Giordani Camila Cunha Oliveira 
Published: December 2019

O artigo em questão trata do Ensino Médio Integrado dentro do atual debate sobre a aprovação da Lei Federal nº 13.415, de 16 de fevereiro de 2017. Tal legislação, a chamada Lei da Reforma do Ensino Médio, alterou a estrutura deste nível de ensino, ignorando experiências brasileiras exitosas, desenvolvidas na última década no nível médio e que, no mínimo, deveriam ter ser ouvidas num debate tão importante. Este estudo se trata, portanto, de uma pesquisa de mestrado, em andamento, que visa demonstrar o mérito do Ensino Médio Integrado (EMI) neste contexto de disputa político-social. Teve como metodologia a pesquisa bibliográfica e documental, fundamentadas em autores como Marx, Manacorda, Saviani, dentre outros, a fim de refletir sobre a finalidade pedagógica e política EMI no âmbito da educação brasileira.
A FORMAÇÃO E ATUAÇÃO DOCENTE DOS PROFESSORES DA EDUCAÇÃO PROFISSIONAL E TECNOLÓGICA: O QUE REVELAM AS PESQUISAS DOS ÚLTIMOS DEZ ANOS?
Authors: Pires Fabíula Tatiane 
Published: December 2019

Em 2018 os Institutos Federais de Educação, Ciência e Tecnologia (IF) completaram dez anos de sua criação. Eles tiveram sua origem a partir da reestruturação dos Centros Federais de Educação Tecnológica (CEFET), das escolas técnicas e agrotécnicas federais e das escolas vinculadas às Universidades Federais, seu marco legal data da promulgação da lei 11.892/08. Nesse período um número significativo de professores ingressou nos IF’s, dada a expansão e a interiorização dos mesmos. Assim, esse trabalho tem como objetivos identificar, analisar e sintetizar a produção científica da área no que se refere à formação e atuação dos docentes da Educação Profissional e Tecnológica (EPT). Para tanto realizou-se um levantamento bibliográfico, no mês de dezembro de 2018, nas seguintes fontes de referência: Revista Brasileira de Educação, Revista Educação & Sociedade, Revista Brasileira da Educação Profissional e GT 8 - Formação de Professores da ANPEd, no período de 2008 a 2018. Os resultados encontrados revelam a predominância de algumas temáticas, a saber: legislação referente a formação de professores da EPT; saberes docentes; formação continuada; conteúdo de formação; atuação marcada pela inserção no mercado de trabalho; identidade em construção.
Bir Ara Fenomenolojisine Doğru: Berzahtaki İslam Sanatı
Authors: GÖZEL Özkan 
Published: December 2019

Bu çalışmada İbn Arabî’nin berzah ve hayal kavramlarından hareketle genel olarak
İslam sanatını, özel olarak da sanat eserini yeni baştan düşünmeyi deniyoruz. Bize göre
İslam sanatı hem güncel hem de metafizik anlamda berzahta (“ara”da) bulunmaktadır. İlk
olarak, bu sanat hâlihazırda “eski” ile “modern” arasında tereddütler geçirmektedir. Bu
zor durumun dezavantajları yanı sıra avantajları vardır. Zira, hakkı verildiği takdirde, bu
arada bulunuş, İslam sanatının zenginleştirici bir imkânına dönüştürülebilir. İkinci olarak,
İslam sanatı tam da metafizik anlamda arada yani berzahta bulunmakta ve gerçekte verimlerini
oradan devşirmektedir. İslam sanatı haddizatında aisthesis’ten ziyade ara-da-lık
ile karakterize olan hayal’e dayanmaktadır. Bu çalışmada biz İslam sanatının metafiziğini
İbn Arabî’ye ait berzah kavramıyla onunla özsel anlamda bağlantılı olan hayal kavramından hareketle yeni baştan düşünmeyi teklif ediyoruz. Bu maksatla da örnekler arasında bir örneğe, Süleymaniye Camisi örneğine başvuruyor ve bu eserin hakikatini “ara” kavramına
müracaatla açıklığa kavuşturmayı deniyoruz. Bu çalışmada aynı zamanda eserden
hareketle bir ara fenomenolojisi geliştirilmek amaçlanmaktadır. İslam sanatını değerlendirirken
onun ardında yatan metafiziğe ve bu arada tasavvuf metafiziğine başvurmak gerekliliği
bu çalışmada altı çizilen başka bir husustur.
Vakfiyesi Işığında Şah Sultan ve Zal Mahmud Paşa Külliyesi
Authors: KAHRAMAN Betül 
Published: December 2019

Bu makalede Osmanlı medeniyetinin en önemli değerlerinden olan vakıflar’ın bir
örneği olarak Şah Sultan ve Zal Mahmud Paşa Vakfı ele alınmıştır. 16. yüzyıl sonunda kurulan
bu vakfın kurucuları II. Selim’in kızı Şah Sultan ile eşi Vezir Zal Mahmud Paşa’nın
hayatı ve kurmuş oldukları vakıflar irdelenmiştir.
Vinclozolin’ in Galleria mellonella L. (Lepidoptera: Pyralidae)’ nın Glukoz Oksidaz, Katalaz ve Ksantin Oksidaz Aktiviteleri Üzerine Etkisi
Authors: ÖZTÜRK Rahile , MALTAŞ ÇAĞIL Esra 
Published: December 2019

Bu çalışmada, özellikle savunma mekanizmasında etkili olan
katalaz enzim aktivitesi, karbonhidrat metabolizmasında rol alan glukoz oksidaz
ile nükleotid metabolizmasında görev alan ksantin oksidaz enzim aktiviteleri
ölçülmüştür. Aktivite sonuçları incelendiğinde; 20, 40 ve 60 ppm vinclozolin
içeren besinle beslenen larvalarda, vinclozilin konsantrasyonundaki artışa
bağlı olarak katalaz ve glukoz oksidaz aktivitelerinin arttığı, ksantin oksidaz
aktivitesinin ise sabit kaldığı gözlenmiştir. Bu çalışma, vinclozolinin, arıcılıkta peteklere zarar veren
ve ekonomik yönden zararlı bir tür olan Galleria mellonella (Lepidoptera: Pyralidae)’ nın bazı enzim
aktiviteleri (Glukoz Oksidaz, Katalaz ve Ksantin Oksidaz) üzerine etkisini
belirlemek amacıyla yapılmıştır. Deney grupları için, stok kültürlerden elde
edilen yumurtalar, farklı dozlarda (20, 40 ve 60 ppm) vinclozolin karıştırılmış
besin içine bırakılmış ve yumurtadan çıkan larvaların bu besinle beslenmeleri
sağlanmıştır. Aynı vinclozolin oranlarında homojenattaki protein
miktarlarındaki değişimleri incelemek için böcekten protein izolasyonu
gerçekleştirilmiştir. Homojenatlardaki toplam protein miktarı Bradford metodu
ile belirlenmiş ve ekstraktlara SDS- PAGE analizi yapılarak protein profilleri
çıkartılmıştır. Elde edilen ekstraktlar, enzim aktivite analizleri için
kullanılmıştır.
Seryum Oksit Katkılı Doğal Obsidyen Camların Mekanik Özellikleri
Authors: AKTAŞ Bülent , YALÇIN Şerife , AÇIKGÖZ Abuzer , ŞERBETÇİ Rahime 
Published: December 2019

Bu
çalışmanın amacı, seryum oksidin (ağırlıkça %0,5-10 CeO2)
eklenmesiyle yüksek mekanik özelliklere sahip doğal obsidyen camların
üretilmesidir. Obsidyen cam örnekleri geleneksel ergitme metodu ile 1300
oC de 2 saat bekletilerek üretilmiştir. Saf
ve CeO2 katkılı obsidyen örneklerinin yoğunluğu Arşimet prensibi ile
belirlenmiştir. Numunelerin sertlik ve kırılma tokluğu, Micro-Vickers çentik
testi kullanılarak ölçülmüştür. CeO2 katkılı obsidyen camın XRD desenleri,
tüm CeO2 katkılarında silikon oksit içerdiğini göstermiştir. CeO2
ilavesi ile obsidyen camın yoğunluğu artmıştır. Mekanik test sonuçları CeO2'nin
obsidyene %1'e kadar ilave edilmesinin sertlikte hafif bir artışa neden
olduğunu gösterdi. Ayrıca, obsidyen cam numunelerinin kırılma tokluğu,
ağırlıkça %5 CeO2 ilave edilerek 1,65 ila 1,91 MPa.m0,5 arasında
değişmiştir. Böylece, obsidyen camların
mekanik özellikleri CeO2 ilavesiyle arttırılabilir.