bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation of a united information space of a research library
Authors: Gerasimenko A. Yu. 
Published: January 2020

Over the past decade, the issue of uncontrolled growth of unsystematic information in Internet has remained acute for the scientific community. The problem of finding relevant information related to the distribution and autonomy of scientific information resources remains. A priority in the field of centralized access to the key scientifically significant sources of information is the creation of a united information space (UIS). The study aims to identify the main models to form systems integrating distributed information resources, and as a result to determine the structure of UIS formation in a research library. Two models were considered and analyzed in the study: a meta-aggregator and an integrated electronic library. During the analysis, elements, structure and a set of functions for users and employees of a research library are revealed for each model. The study allowed the drawing of the following conclusions:• The choice of a model for the UIS formation depends mostly on the formulation of tasks, the solution of which is the purpose of creating a system, as well as on the technological potential of the organizations involved in the process.•Multifunctionality of the system allows simultaneous use of the above-mentioned formation models.• Adding the element of interactivity to the structure of UIS of the research library will allow timely monitoring of changes in the information needs of scientists, reduction of time, labor and financial costs of both the library and a user. The article presents the criteria for choosing a model. For the first time the optimal effective structure of the UIS in the research library is described.
The Relationship of Nutmeg (Myristica fragrans Houtt.) Tidore, Ternate and Bogor Based on Morphological Marker
Authors: Arlianti Tias , Wirnas Desta , Sobir NFN , Rostiana Otih 
Published: January 2020

<em>Banda Nutmeg (</em>Myristica fragrans<em>), is one of Indonesia's main spices commodities. Maluku Island, North Maluku, Siau, and Papua are the center of origins and center of nutmeg diversity; whereas, Bogor is the largest nutmeg cultivation area in West Java. The diversity and relationship between Bogor nutmeg with Maluku nutmeg have not been studied, even though it is crucial for local varieties selection and seeds provision. The study aimed to determine the diversity and relationship of nutmegs from Tidore, Ternate, and Bogor. The experiment was conducted in eight locations: Tidore (Gurabunga and Jaya), Ternate (Marikurubu), and Bogor (Cigombong, Ciawi, Leuwisadeng, Sukajadi, and Tamansari) from November 2017 - December 2018. Materials used were 46 nutmeg accessions of 8 – 30 year old plants with good growth and known of their origin. The experiments were performed using direct observation methods on habitus, leaf, fruit, seed, mace, and flower followed IPGRI descriptor. The results showed that qualitative diversity was</em> <em>observed in the fruit shape, shape of fruit-based and fruit-tip, fruit color, and tree shape. Mace thickness was the most substantial diversity for the quantitative character (50.38 %). The difference within intra-population in all aspects observed was low, except for the fruit character and mace weight. The genetic relatedness of the Bogor population was closer to Ternate (60 %) than Tidore (46 %). The genetic relationship amongst five Bogor populations found to be very close. Further, Leuwisadeng, Tamansari, and Sukajadi populations were found to have the highest genetic relationship and similarity (80 %).</em>
Looking Ahead of the Bit Using Surface Drilling and Petrophysical Data: Machine-Learning-Based Real-Time Geosteering in Volve Field
Authors: Gupta Ishank , Tran Ngoc , Devegowda Deepak , Jayaram Vikram , Rai Chandra , Sondergeld Carl , Karami Hamidreza 
Published: January 2020

SummaryPetroleum reservoirs are often associated with multiple target zones or a single zone adjacent to nonproductive intervals. Real-time geosteering therefore becomes important to remain in zone or to dynamically steer toward a target. This requires knowledge of the petrophysical/rock mechanical properties of the rock surrounding the bit. Although logging while drilling can provide this information, a cost-effective and almost-real-time solution is lacking. In general, there is a depth lag, and therefore, a time delay, between what the logging-while-drilling sub relays to the surface and the bit performance. This study focuses on relating drill-bit- and drillstring-performance data in a machine-learning (ML) workflow to predict the lithology at the bit while drilling. The method we are proposing offers several advantages in terms of cost and time savings for real-time geosteering applications, where going out of zone requires costly intervention.In this study, we have used a public data set from Volve Field on the Norwegian continental shelf. Within our proposed workflow, as a first step, logs sensitive to lithology [such as density, gamma ray (GR), and sonic] are grouped into three electrofacies. We also had access to core data, which helped us interpret the electrofacies in terms of mineralogy. The three electrofacies corresponded to quartz-rich (sandstone/siltstone), clay-rich (shale), and carbonate-rich (limestone) lithologies.The next step is to predict the electrofacies using various measurement-while-drilling (MWD) variables, such as rate of penetration (ROP), weight on bit (WOB), and several others that are monitored in real time. Supervised classification algorithms were used to relate real-time surface measurements to lithology. The algorithms were able to predict lithology in test wells with more than 80% accuracy. These results, although encouraging, constitute a small step toward drilling-automation/advisory systems. The development of such systems can prevent costly out-of-zone drilling and minimize rig time and equipment use, thereby potentially reducing capital expenditures. This study was specifically performed in Volve Field in the North Sea using petrophysical and surface drilling data from vertical wells. However, the workflow has a potential to be extended to other formations in other fields in different well types.
Experimental Correlations for the Performance and Aperture Selection of Wire-Wrapped Screens in Steam-Assisted Gravity Drainage Production Wells
Authors: Montero Pallares Jesus David , Wang Chenxi , Haftani Mohammad , Nouri Alireza 
Published: January 2020

Summary
Wire-wrapped screens (WWSs) are one of the most-commonly used devices by steam-assisted gravity drainage (SAGD) operators because of the capacity to control plugging and improve flow performance. WWSs offer high open-to-flow area (OFA) (6 to 18%) that allow a high release of fines, hence, less pore plugging and accumulation at the near-screen zone. Over the years, several criteria have been proposed for the selection of aperture sizes on the basis of different industrial contexts and laboratory experiments. Generally, existing aperture-sizing recommendations include only a single point of the particle-size distribution (PSD). Operators and academics rely on sand-control testing to evaluate the performance of sand-control devices (SCDs). Scaled laboratory testing provides a straightforward tool to understand the role of flow rate, flowing phases, fluid properties, stresses, and screen specifications on sand retention and flow impairment.
This study employs large-scale prepacked sand-retention tests (SRTs) to experimentally assess the performance of WWSs under variable single-phase and multiphase conditions. The experimental results and parametric trends are used to formulate a set of empirical equations that describe the response of the WWS. Several PSD classes with various fines content and particle size are tested to evaluate a broad range of PSDs. Operational procedures include the coinjection of gas, brine, and oil to emulate aggressive conditions during steam-breakthrough events.
The experimental investigation leads to the formulation of predictive correlations. Additional PSDs were prepared to verify the adequacy of the proposed equations. The results show that sanding modes are both flow-rate and flowing-phase dependent. Moreover, the severity or intensity of producing sand is greatly influenced by the ratio of grain size to aperture size and the ability to form stable bridges. During gas and multiphase flow, a dramatic amount of sanding was observed for wider apertures caused by high multiphase flow velocities. However, liquid stages displayed less-intense transient behaviors. Remarkably, WWSs rendered an excellent flow performance even for low-quality sands and narrow apertures. Although further and more complete testing is required, empirical correlations showed good agreement with experimental results.
Emergency Department and Inpatient Utilization among U.S. Older Adults with Multiple Chronic Conditions: A Post-Reform Update
Authors: Ahn SangNam , Hussein Mustafa , Mahmood Asos , Smith Matthew Lee 
Published: January 2020

Abstract
Background. The Affordable Care Act (ACA) was enacted to enhance access to care primarily among nonelderly and low-income populations; however, several provisions addressed key determinants of emergency department (ED) and inpatient visits among Medicare beneficiaries over age 65 years. We take stock of the overall changes in these visits among older Medicare beneficiaries, focusing on those with multiple chronic conditions (MCCs), and provide a nationally representative post-reform update.
Methods. We analyzed a sample of 32,919 older adults (65+) on Medicare from the 2006-2015 Medical Expenditure Panel Survey (MEPS). Using a survey-weighted two-part model, we examined changes in ED visits, inpatient visits, and length of stay (LOS) by MCC status, before (2006-2010), during (2011-2013), and after the ACA (2014-2015).
Results. Prior to the ACA, 18.1% of Medicare older adults had ≥1 ED visit, whereas 17.1% had ≥1 inpatient visits, with an average of 5.1 nights/visit. Following ACA reforms, among those with 2+ chronic conditions, the rate of ever having an ED visit increased by 4.3 percentage points [95% confidence intervals [CI]: 2.5, 6.1, p < 0.01], whereas the rate of inpatient visits decreased by 1.4 percentage points [95%CI: -2.9, 0.2, p < 0.1], after multivariable adjustment.
Conclusions. We found sizable increases in ED visits and nontrivial decreases in inpatient visits among older Medicare beneficiaries with MCCs, underscoring the continuing need for improving access to and quality of care among older adults with MCCs to decrease reliance on the ED and reduce preventable hospitalizations.
Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period
Authors: Deis Amanda S. , Schnetz Michael P. , Ibinson James W. , Vogt Keith M 
Published: January 2020

Abstract
Background : Awareness with recall under general anesthesia remains a rare but important issue that warrants further study.
Methods : We present a series of seven cases of awareness that were identified from provider-reported adverse event data from the electronic anesthesia records of 647,000 general anesthetics.
Results : The low number of identified cases suggests an under-reporting bias. Themes that emerge from this small series can serve as important reminders to anesthesia providers to ensure delivery of an adequate anesthetic for each patient. Commonalities between a majority of our identified anesthetic awareness cases include: obesity, use of total intravenous anesthesia, use of neuromuscular blockade, and either a lack of processed electroencephalogram (EEG) monitoring or documented high depth of consciousness index values. An interesting phenomenon was observed in one case, where adequately-dosed anesthesia was delivered without technical issue, processed EEG monitoring was employed, and the index value suggested an adequate depth of consciousness throughout the case.
Conclusions : Provider-reported adverse event data in the immediate post-operative period are likely insensitive for detecting cases of intraoperative awareness. Though causation cannot firmly be established from our data, themes identified in this series of cases of awareness with recall under general anesthesia provide important reminders for anesthesia providers to maintain vigilance in monitoring depth and dose of anesthesia, particularly with total intravenous anesthesia.
Oral Impact on Daily Performance (OIDP) scale for use in Sri Lankan Adolescents: a cross sectional modification and validation study
Authors: Amilani Uttara , Jayasekara Prasanna , Perera Irosha R , Carter Hannah E , Senanayake Sameera , Kularatna Sanjeewa 
Published: January 2020

Abstract
Background
Oral Health Related Quality of Life (OHRQoL) measures play an important role in understanding subjective patient experiences in oral health care. The Oral Impact on Daily Performance (OIDP) scale is a validated OHRQoL tool that measures the impact and extent to which an individual’s daily activities may be compromised by their oral health. The aim of this study was to modify and validate a Sinhalese version of the OIDP for use in Sri Lankan adolescents.

Methods
Stage I involved cultural adaptation of the tool through translation and modification. Stage II involved the exploring factor structure and validity assessment. After translation and cultural adaptation, stage II was conducted among 220 students aged 15-19 in the Gampaha district, Sri Lanka. Participants completed the modified OIDP scale along with questions on self-reported perceived oral health problems and treatment need which were used to assesses the concurrent validity of the modified OIDP scale. Factorability was assessed by inspection of correlation matrix, Kaiser-Meyer-Olkin and Bartlett's Test of Sphericity as a measure of sampling adequacy. An exploratory factor analysis was carried out using Principal Component Analysis (PCA) method and factors were rotated using the oblimin method.

Results
The Kaiser-Meyer-Olkin measure was 0.87 and Bartlett’s test of Sphericity was significant (p<0.001) Cronbach’s alpha was calculated as 0.88, indicating a high level of internal consistency of the modified OIDP scale. The PCA is produced two factors with Eigen values ranging from 1.12 to 4.40, explaining 70.0% of total variance. Concurrent validity was satisfactory as the OIDP score increased when the adolescents’ perceived oral health decreased. The final modified OIDP consists of eight self-reported items which assesses the impact severity of eight daily performances over past three months. Participant scores ranged from 0 to 24 out of a worst possible score of 40, and nearly 48% of the responders reported at least one impact during past three months. The most prevalent oral health impact related to chewing and enjoying foods, reported by 36.8% of respondents.

Conclusion
This study suggests that the modified OIDP scale has promising psychometric properties and is appropriate for use among adolescents in Sri Lanka.
Women’s knowledge of and attitudes toward cervical cancer and cervical cancer screening in Zanzibar, Tanzania: a cross-sectional study
Authors: Weng Qiao , Jiang Jie , Haji Fatma Mrisho , Nondo Lamlet Hassan , Zhou Huaijun 
Published: January 2020

Abstract
Background: Cervical cancer is the most common cancer and the leading cause of cancer death among women in Tanzania. Knowledge of and willingness to receive a cervical cancer screening are important determinants of prevention. This study aimed to describe women's awareness of cervical cancer and to explore the attitudes toward, acceptability of and barriers to cervical cancer screening (CCS) in Zanzibar.
Methods: A cross-sectional study was conducted from March to June 2018 involving 1483 women from 10 districts in Zanzibar who responded to questionnaires concerning their general demo-graphic characteristics, screening willingness and awareness of cervical cancer. Chi-square tests, analysis of variance (ANOVA) and stepwise multiple regression were conducted using STATA 15.1 software.
Results: The average total knowledge score (TKS) was 7.84±5.32 on a 23-point scale. Educational level and family income were positively correlated with the TKS. Previous schistosomiasis history and family genetic disease history were strong predictors of screening willingness. Women were less likely to be screened freely if they had 7 or more deliveries and were unaware of any previous family tumor history. Age and educational level were negatively associated non-free screening willingness, while family income was positively associated; being divorced/widowed or single and being unaware of any previous family tumor history were predictors of screening reluctance, while previous disease history was a strong predictor of non-free screening willingness. Fear of screening and inconvenience were the primary concerns among the Zanzibari interviewees. Compared to the 20-49 age group, more women in the less than 20 and 50 or more age groups thought cervical cancer screening was not necessary. The highest rate of cognitive accuracy in regard to cervical cancer warning signs and risk factors was only 37.76%.
Conclusions: The findings revealed that knowledge of cervical cancer was poor. Educational level, family income and awareness of previous disease history were significant influencing factors of screening uptake. Specific awareness programs to increase knowledge of cervical cancer and screening willingness should be designed and implemented in the public without delay, especially for younger and elderly women.
Keywords: Knowledge, Cervical cancer, Screening, Zanzibar
Individual and healthcare system factors influencing antenatal care attendance in Saudi Arabia
Authors: Alanazy Wdad , Brown Amy 
Published: January 2020

Abstract
Background: The World Health Organisation recommends women have at least four antenatal care visits (ANC) during a low risk pregnancy. However, in Saudi Arabia, many mothers miss these appointments, placing their health and that of their baby at risk. Limited research which has explored why this is happening has focused on low maternal education or personal barriers such as lack of transport . The aim of the current research was therefore to understand what factors at the individual and healthcare systems level were associated with missing antenatal care in Saudi Arabia.

Methods: Two hundred and forty-two pregnant women in their third trimester completed a questionnaire examining their care attendance (appointments missed, planned future attendance, timing of first appointment) alongside barriers to attending care. These included maternal demographic background, health literacy, personal barriers, health care system factors and staff communication).

Results: Over half of women surveyed had missed at least one appointment and a third had delayed their care. Mothers who had missed or delayed appointments blamed health care system factors such as poor clinic facilities and waiting times. Attending care was not associated with maternal education or literacy, although mothers with a lower level of literacy were more likely to delay care. However, perceptions of staff communication, consistency and care were lower amongst mothers who had missed at least one appointment.

Conclusions: Although in previous research health professionals believe it is maternal education that leads to poor attendance, in our sample at least, perceptions of staff communication and clinic facilities were instead associated with attendance. Making changes at the health care level e.g. through adapting clinic times and investing in staff training may increase antenatal care attendance in Saudi Arabia.
Effects of non-surgical periodontal therapy on systemic inflammation and metabolic markers in patients undergoing haemodialysis and/or peritoneal dialysis: a systematic review and meta-analysis
Authors: Yue Hui , Xu Xinxin , Liu Qin , Li Xiaozhi , Xiao Yiting , Hu Bo 
Published: January 2020

Abstract
Background: This systematic review aimed to investigate whether non-surgical periodontal therapy (NSPT) can reduce systemic inflammatory levels and improve metabolism in patients undergoing haemodialysis (HD) and/or peritoneal dialysis (PD).
Methods: Electronic databases (PubMed, EMBASE, CENTRAL, CNKI, and WFPD) were searched for randomized controlled trials (RCTs) performed through July 2019. The risk of bias within studies was assessed with the Cochrane Collaboration’s risk assessment tool. The systemic inflammatory and metabolic outcomes included the highly sensitive C-reactive protein (hs-CRP), interleukin 6 (IL-6), tumour necrosis factor-a (TNF-a), the albumin (Alb), and lipid metabolite levels Meta-analyses (MAs) were performed to calculate the overall effect size where appropriate.
Results: Five RCTs were included in this study. Compared with untreated periodontitis groups, the dialysis patients after NSPT significantly showed decreased hs-CRP levels at less than or equal to 2 months (standardized mean difference: -1.53, 95% confidence interval -2.95 to -0.11). No significant difference was found in IL-6 and Alb levels following NSPT at either the 3- or 6- month follow-ups. No MAs could be performed on the TNF-a level and the lipid metabolic markers.
Conclusions: NSPT can moderately reduce serum hs-CRP levels in HD and/or PD patients, but did not significantly change IL-6 or Alb levels. For TNF-a and lipid metabolism markers, no sufficient evidence supports that these levels are changed after NSPT. Additional scientific research is necessary to assess the effects of NSPT on systemic inflammation and metabolic parameters in dialysis patients.
Effect of gga-miR-155 on Cell Proliferation, Apoptosis and invasion of Marek’s disease Virus (MDV) transformed cell line MSB1 by targeting RORA
Authors: Ding Ke , Yu Zuhua , Yu Chuan , Jia Yanyan , He Lei , Liao Chengshui , Li Jing , Zhang Chunjie , Li Yingju , Wu Tingcai , Cheng Xiangchao , Zhou Zhiyu , Yu Zuling 
Published: January 2020

Abstract
Background Marek's disease (MD) is an avian lymphoproliferative neoplasm caused by the oncogenic Marek's disease virus (MDV). MicroRNAs (miRNAs) act as oncogenes or tumor suppressors in most cancers. The gga-miR-155 is downregulated in the MDV-infected chicken tissues or lymphocyte lines, although its exact role in tumorigenesis remains unclear. The aim of this study was to analyze the effects of gga-miR-155 on the proliferation, apoptosis and invasiveness of an MDV-transformed lymphocyte line MSB1 and elucidate the underlying mechanisms.Results The expression level of gga-miR-155 was manipulated in MSB1 cells using specific mimics and inhibitors. While overexpression of gga-miR-155 increased proliferation, decreased the proportion of G1 phase cells relative to that in S and G2 phases, reduced apoptosis rates and increased invasiveness. However, its downregulation had the opposite effects. Furthermore, gga-miR-155 directly targeted the RORA gene and downregulated its expression in the MSB1 cells.Conclusion The gga-miR-155 promotes the proliferation and invasiveness of the MDV-transformed lymphocyte line MSB1 and inhibits apoptosis by targeting the RORA gene.