bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research of R/V “Akademik Tryoshnikov” hull structures response to ice actions during the first stage of the expedition “Transarktika-2019”
Authors: Maksimova P. V. , Chernov A. V. , Likhomanov V. A. , Krupina N. A. , Likhomanov V. A. 
Published: March 2020

At present, oil-producing offshore structures, as well as transport vessels transporting oil products extracted in the seas of the Russian Arctic are equipped with ice load monitoring systems (ILMS) to prevent environmental disasters. The ice-resistant self-propelled platform (IRSPP) that is under construction now, according to the design should be equipped with this system. First of all this system is the main system for ensuring the platform’s safety in ice conditions, and secondly makes the platform’s hull a unique tool for solving a wide range of tasks to study the effects of ice on any construction.The main goal of the research during the expedition “Transarktika-2019” was to obtain the necessary data for the development of an ice load monitoring system of the constructing IRSPP “North Pole” and testing the prototype of the ILMS at long vessel’s drift in ice.The measurements of stresses in the hull structures of the R/V “Akademik Tryoshnikov” were carried out during impacts on ice ridges and during ice compressions.The standard ship ice load monitoring system (SILMS) of the R/V “Akademik Tryoshnikov” and strain gauges additionally installed on the frames and a shell plating in the middle part of the hull were used to perform the measurements.The analysis of the obtained data showed that the maximal loads on the hull occurred during the forcing of ice ridges but the level of maximum stresses was not a danger to the hull.Compressions during the drift did not have a strong effect on the ship’s hull. The data obtained made it possible to identify a number of features for the operation of ILMS in similar conditions.Based on the results of the expedition research, recommendations for the design of the architecture of the ILMS for IRSPP were issued. The results of further analysis of the obtained materials will be used in the development of data processing algorithms for ILMS for IRSPP, as well as for the development of the prospective programs of scientific research of deformation, fracture and other processes of various scales that occur in drifting ice during the future drifts of the IRSPP “North Pole”.The authors have no competing interests.
Assessment of risk factors for multifocal atherosclerosis in the workers of the main professions of coal enterprises in the South of Kuzbass
Authors: Filimonov E. S. , Korotenko O. Yu. , Rumpel O. A. , Blazhina O. N. 
Published: March 2020

Introduction. The problem of high mortality from cardiovascular diseases is caused, among other things, by asymptomatic atherosclerosis, which proceeds latently for a long time and manifests itself as a serious vascular catastrophe, which is of particular importance for people working at production facilities with difficult and dangerous working conditions.The aim of the study was to assess the risk factors for atherosclerosis and the state of the vascular wall in the workers of the main professions of coal enterprises in the South of Kuzbass.Material and methods. In total, the study included 384 people (men), of whom 266 were the workers in coal mines in the South of Kuzbass and 118 people who were not employed in the coal industry, aged 40 to 55 years. The diagnosis of atherosclerosis was carried out on the ultrasound system “Vivid E9” of the manufacturing company GE using a linear sensor for measuring the thickness of the intima-media complex and visualization of atherosclerotic plaques. To identify significant risk factors, anthropometric, anamnestic data, indices of lipid and carbohydrate metabolism, and the presence of arterial hypertension were studied.Results. Significant differences in the frequency of asymptomatic atherosclerosis in the form of an increase in intima-media thickness by more than 1 mm and / or the presence of atherosclerotic plaques in both groups were not found: 60.2% among the miners and 62.3% among non-coal mining workers (p=0.703); at the same time, the percentage of detection of atherosclerotic plaques in arteries was significantly lower among coal workers — 46.9% versus 60.5% among people in the comparison group (p=0.016). The common risk factors for all examined subjects were arterial hypertension and increased level of glycated hemoglobin; in turn, in coal miners additional risk factors were increased values of low density lipoproteins and waist-hip index, as well as burdened heredity for cardiovascular diseases, and among the individuals not employed in the coal industry it was smoking.Conclusions. The most significant risk factors for atherosclerosis in coal industry workers were arterial hypertension, raised values of glycated hemoglobin, low density lipoproteins and waist-hip index, as well as burdened heredity for cardiovascular diseases. Significant differences in the frequency of asymptomatic atherosclerosis in the form of an increase in the thickness of the intima-media complex of the main arteries and the presence of atherosclerotic plaques in both groups were not established, but the percentage of the detection of atherosclerotic plaques was lower among coal miners.The authors declare no conflict of interests.
Influence of violations of autonomic regulation on the development of occupational polyneuropathy of the upper extremities in Kuzbass miners
Authors: Gidayatova M. O. , Fleishman A. N. , Yamshchikova A. V. , Martynov I. D. 
Published: March 2020

Introduction.Active coal mining in Kuzbass, with its unfavorable climatic and environmental conditions, necessitates the study of occupational diseases of workers in this industry. One of the most common occupationally caused diseases of miners is polyneuropathy of the upper extremities.The aim of the studyis to assess the effect of autonomic disorders on the course of occupational upper limb polyneuropathy in workers of the Kuzbass coal industry using various methods of analyzing heart rate variability.Materials and methods. 52 employees of coal enterprises aged from 43 to 64 years with the established diagnosis of “polyneuropathy of the upper extremities” were examined. The control group consisted of 16 healthy volunteers of the same age, engaged mainly in mental or light physical labor. Electroneuromyography was performed to assess the degree of damage to peripheral nerve fibers. Spectral and nonlinear parameters of heart rate variability were used to determine the state of autonomic regulation. The Mann-Whitney criterion was used to assess the statistical significance of differences between the study groups.Results.3 groups of patients with polyneuropathy were identified according to the severity of violations of impulse conduction in the peripheral nerves. In subjects with mild, initial disturbances of pulse conduction (n=8, 15.4%), a decrease in parasympathetic influence is determined, which is manifested by a statistically significant decrease in the power of high frequency oscillations of the heart rate variability spectrum. With moderate signs of polyneuropathy (28 cases, 53.9%), there is a shift in the autonomic balance towards sympathetic activation; a statistically significant increase in very low-frequency fluctuations in heart rate variability indicates an increase in the influence of suprasegmental autonomic centers. In subjects with gross violations of the peripheral nerve impulses (n=16, 30.7%), there is a decrease in the power of oscillations in all frequency ranges of heart rate variability.Conclusions. The obtained data confirm the influence of autonomic regulation on the course of occupational polyneuropathy.The authors declare no conflict of interests.
Relationship of subdepressive symptoms with phases of emotional burnout in representatives of “assisting professions”
Authors: Vlakh N. I. , Danilov I. P. , Gugushvili M. A. , Paneva N. Ya. , Logunova T. D. 
Published: March 2020

Introduction. The study of the problems of human stress resistance in various professions has shown that prolonged exposure to stress leads to such adverse consequences as a decrease in the overall mental stability of the body, the emergence of a sense of dissatisfaction with the results of their activities, the tendency to refuse to perform tasks in situations of increased demands, failures and defeats. Analysis of the factors that cause such symptoms in various activities has shown that there are a number of professions in which a person begins to experience a sense of internal emotional emptiness due to the need for constant contact with other people.The aim of the study is to study the subdepressive symptoms in accordance with the phases of emotional burnout.Materials and methods. The study involved 465 people, of whom 219 men and 246 women were representatives of various professional groups. The indicators of emotional burnout, including three phases-stages: “Tension”, “Resistance”, “Exhaustion” — each of which consists of 4 symptoms, are considered.Results. The correlation coefficient of the level of formation of symptoms of emotional burnout according to the method of V.V. Boyko with the level of severity of each of the components of emotional burnout according to the MBI method are calculated.Conclusions. It was found that people whose personal and professional lives are filled with meaning are only slightly or moderately susceptible to burnout syndrome. On the contrary, subjects with an existential vacuum showed, according to the MVI test, a high degree of severity of burnout syndrome.The authors declare no conflict of interests
Effectiveness of ischemic preconditioning for correction of neuroautonomic disorders in vibration disease
Authors: Yamshchikova A. V. , Fleishman A. N. , Gidayatova M. O. 
Published: March 2020

Introduction. Vibration disease, affecting the autonomic-vascular regulation at different levels, disrupts the balance of sympathetic and parasympathetic influences with the formation of vasospasm. The development of cardiac autonomic neuropathy leads to a worsening of the prognosis for the life of patients, and therefore, the search for effective methods for correcting autonomic disorders is an urgent task in the treatment of vibration disease.The aim of the study is to evaluate the effectiveness of ischemic preconditioning for the correction of neurovegetative manifestations of vibration disease.Materials and methods. A comparative assessment of the initial parameters of heart rate variability was carried out in the main group of patients with an established diagnosis of vibration disease (32 people), and in the control group (25 people who had never worked under the influence of industrial vibration). The main group of patients underwent ischemic preconditioning of the upper extremities for 4 days, followed by monitoring of heart rate variability. The Mann-Whitney criteria were used to compare two independent samples and Wilcoxon to assess the significance of changes in indicators before and after exposure. Values at p<0.05 were considered statistically reliable.Results. An initial decrease in the power level of all spectral parameters of heart rate variability in the main group with the formation of relative sympathicotonia and a decrease in the values of the approximated entropy was revealed. After ischemic preconditioning, heart rate variability significantly increases, which indicates a decrease in the severity of autonomous neuropathy and an improvement in the prognosis for life.Conclusions. In patients with vibration disease, all parts of the peripheral and central autonomic nervous system are involved in pathogenesis with the formation of persistent sympathicotonia and violation of regulatory mechanisms. Ischemic preconditioning can affect the identified disorders by inducing an adaptive vagal response.The authors declare no conflict of interests.
Radonotherapy in restoring statokinetic functions in the patients with occupational joint damage
Authors: Gordeeva R. V. , Filimonov S. N. , Kuzmenko O. V. , Kireeva L. N. , Martynova E. A. , Anishchenkova T. I. 
Published: March 2020

The results of the use of natural radon water in the form of general baths in patients working in the coal mining and metallurgical industry, with occupational diseases of the joints and spine, at the stage of rehabilitation are presented. Studies have shown that the course application of radon therapy has a pronounced analgesic and anti-inflammatory effect, a general sedative effect helps to restore the volume of movements in the affected joints, normalizes the statokinetic functions of the musculoskeletal system, slows down the progression of the joint process and the development of dystrophic changes in the musculoskeletal system.Indicators of statodynamic functions of the musculoskeletal system in patients with occupational diseases of the joints and spine in the rehabilitation system against the background of course use of natural radon waters in the form of shared baths were studied. The aim of the study is to explore the effect of radon waters of natural origin on the dynamics of statodynamic parameters according to the data of a stabilometric study in patients working in the coal mining and metallurgical industry, with occupational diseases of the joints and spine.Patients with occupational diseases of the joints and spine in rehabilitation were prescribed general radon baths (the main group). The control group of patients received freshwater baths. Before and after treatment were carried out studies of the static-dynamic functions stabiiloplatform (soft ware-hardware complex for clinical motion analysis “Biomechanics” published by the scientific-medical firm MBN), with the help of which the indicator of the common center of mass, the flexor setting up of the thigh, the coefficient of weight load on the foot, the inter-limb asymmetry, the vertical stance was determined in the initial position and in the Romberg position.The use of common radon baths in the main group allowed to normalize the statokinetic functions of the musculoskeletal system in the form of reducing the period of alignment of the pelvic flexor installations and asymmetry of the distribution of weight load on the affected limb; increasing the level of adaptation of patients to functional loads against the background of reducing pain and inflammatory syndrome. There were no significant changes in these indicators in the control group. The use of general radon baths on the rehabilitation stage in patients working in the coal mining and metallurgical industry, with occupational diseases of the joints and spine, helps to restore the statodynamic functions of the musculoskeletal system, the disappearance of pain syndrome, and reduces inflammation.The authors declare no conflict of interests.
On the issue of manganese intoxication
Authors: Gavrylyshena K. V. , Gurevich E. B. , Semenikhin V. A. , Strizhakov L. A. , Filimonov S. N. , Chasovskikh E. V. 
Published: March 2020

Currently, the proportion of workers exposed to manganese compounds is quite high, but due to increased safety measures and changes in working conditions, the number of new cases of chronic occupational manganese intoxication has decreased significantly. an attempt has been madeAn attempt has been made to highlight the difficulties of differential diagnosis of occupational chronic manganese intoxication and other neurological diseases on the example of clinical cases of examination of persons with extrapyramidal system lesions in the form of early development of Parkinson’s disease. The assessment of complaints, medical history, neurological status, laboratory tests, and instrumental studies to find the probable cause of Parkinsonism was carried out. The interest of the observations lies in the difficulty of interpreting the data obtained and the importance of studying the professional route of patients. Magnetic resonance imaging of the brain, electromyography of the extremities, electroencephalography, echoencephalography, the study of the concentration of metabolites characteristic of Niemann-Pik disease, copper indicators in the blood help in making a correct diagnosis.When examining a contingent of people working in contact with manganese compounds, if they suspect chronic occupational manganese intoxication, it is important consider other diseases that lead to the development of Parkinson’s disease.The authors declare no conflict of interests.
Milrinone for refractory cerebral vasospasm with delayed cerebral ischemia
Authors: Abulhasan Yasser B. , Ortiz Jimenez Johanna , Teitelbaum Jeanne , Simoneau Gabrielle , Angle Mark R. 
Published: March 2020

OBJECTIVEIntravenous (IV) milrinone is a promising option for the treatment of cerebral vasospasm with delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). However, data remain limited on the efficacy of treating cases that are refractory to standard therapy with IV milrinone. The aim of this study was to determine predictors of refractory vasospasm/DCI despite treatment with IV milrinone, and to analyze the outcome of rescue therapy with intraarterial (IA) milrinone and/or mechanical angioplasty.METHODSThe authors conducted a retrospective cohort study of all patients with aSAH admitted between 2010 and 2016 to the Montreal Neurological Institute and Hospital. Patients were stratified into 3 groups: no DCI, standard therapy, and rescue therapy. The primary outcome was frequency of DCI-related cerebral infarction identified on neuroimaging before hospital discharge. Secondary outcomes included functional outcome reported as modified Rankin Scale (mRS) score, and segment reversal of refractory vasospasm.RESULTSThe cohort included 322 patients: 212 in the no DCI group, 89 in the standard therapy group, and 21 in the rescue therapy group. Approximately half (52%, 168/322) were admitted with poor-grade aSAH at treatment decision (World Federation of Neurosurgical Societies grade III–V). Among patients with DCI and imaging assessing severity of vasospasm, 62% (68/109) had moderate/severe radiological vasospasm on DCI presentation. Nineteen percent (21/110) of patients had refractory vasospasm/DCI and were treated with rescue therapy. Targeted rescue therapy with IA milrinone reversed 32% (29/91) of the refractory vasospastic vessels, and 76% (16/21) of those patients experienced significant improvement in their neurological status within 24 hours of initiating therapy. Moderate/severe radiological vasospasm independently predicted the need for rescue therapy (OR 27, 95% CI 8.01–112). Of patients with neuroimaging before discharge, 40% (112/277) had developed new cerebral infarcts, and only 21% (23/112) of these were vasospasm-related. Overall, 65% (204/314) of patients had a favorable functional outcome (mRS score 0–2) assessed at a median of 4 months (interquartile range 2–8 months) after aSAH, and there was no difference in functional outcome between the 3 groups (p = 0.512).CONCLUSIONSThe aggressive use of milrinone was safe and effective based on this retrospective study cohort and is a promising therapy for the treatment of vasospasm/DCI after aSAH.
Preoperative embolization versus no embolization for WHO grade I intracranial meningioma: a retrospective matched cohort study
Authors: Przybylowski Colin J. , Zhao Xiaochun , Baranoski Jacob F. , Borba Moreira Leandro , Gandhi Sirin , Chapple Kristina M. , Almefty Kaith K. , Sanai Nader , Ducruet Andrew F. , Albuquerque Felipe C. , Little Andrew S. , Nakaji Peter 
Published: March 2020

OBJECTIVEThe controversy continues over the clinical utility of preoperative embolization for reducing tumor vascularity of intracranial meningiomas prior to resection. Previous studies comparing embolization and nonembolization patients have not controlled for detailed tumor parameters before assessing outcomes.METHODSThe authors reviewed the cases of all patients who underwent resection of a WHO grade I intracranial meningioma at their institution from 2008 to 2016. Propensity score matching was used to generate embolization and nonembolization cohorts of 52 patients each, and a retrospective review of clinical and radiological outcomes was performed.RESULTSIn total, 52 consecutive patients who underwent embolization (mean follow-up 34.8 ± 31.5 months) were compared to 52 patients who did not undergo embolization (mean follow-up 32.8 ± 28.7 months; p = 0.63). Variables controlled for included patient age (p = 0.82), tumor laterality (p > 0.99), tumor location (p > 0.99), tumor diameter (p = 0.07), tumor invasion into a major dural sinus (p > 0.99), and tumor encasement around the internal carotid artery or middle cerebral artery (p > 0.99). The embolization and nonembolization cohorts did not differ in terms of estimated blood loss during surgery (660.4 ± 637.1 ml vs 509.2 ± 422.0 ml; p = 0.17), Simpson grade IV resection (32.7% vs 25.0%; p = 0.39), perioperative procedural complications (26.9% vs 19.2%; p = 0.35), development of permanent new neurological deficits (5.8% vs 7.7%; p = 0.70), or favorable modified Rankin Scale (mRS) score (a score of 0–2) at last follow-up (96.0% vs 92.3%; p = 0.43), respectively. When comparing the final mRS score to the preoperative mRS score, patients in the embolization group were more likely than patients in the nonembolization group to have an improvement in mRS score (50.0% vs 28.8%; p = 0.03).CONCLUSIONSAfter controlling for patient age, tumor size, tumor laterality, tumor location, tumor invasion into a major dural sinus, and tumor encasement of the internal carotid artery or middle cerebral artery, preoperative meningioma embolization intended to decrease tumor vascularity did not improve the surgical outcomes of patients with WHO grade I intracranial meningiomas, but it did lead to a greater chance of clinical improvement compared to patients not treated with embolization.
TRANSFORMASI TOKOH BISMA DALAM CERPEN “PEREMPUAN YANG INGIN MEMBUNUH BISMA” KARYA GANUG NUGROHO ADI
Authors: Nasihin Agus 
Published: March 2020

Transformasi dalam bentuk karya sastra modern merupakan salah satu upaya pelestarian, pemertahanan eksistensi, dan penafsiran kembali konsep, nilai, dan norma-norma lama secara kontekstual. Dengan demikian, perlu adanya contoh analisis terhadap karya sastra yang berlatar belakang transformasi. Penelitian ini merupakan salah satu contoh analisis terhadap cerpen “Perempuan yang Ingin Membunuh Bisma” karya Ganug Nugroho Adi. Penelitian terhadap cerpen ini dimaksudkan untuk mengetahui bentuk transformasinya. Berdasar pada kisah pewayangan Bisma, transformasi secara utuh terjadi pada alur cerpen “Perempuan yang Ingin Membunuh Bisma”. Tidak ada alur peristiwa yang menyimpang dari hipogramnya. Demikian pula dengan nama-nama tokoh yang muncul dalam cerpen ini sama persis dengan nama-nama dalam kisah pewayangan tentang kehidupan Bisma. Yang membedakan cerpen “Perempuan yang Ingin Membunuh Bisma” dengan hipogramnya adalah penguatan pada unsur tema dan pemuatan nilai-nilai ideologis feminisme.

Kata kunci: transformasi, hipogram, cerita pendek