bluuebunny/crossref_metadata_2025_split huggingface dataset:
Willingness to adopt wearable devices with behavioral and economic incentives by health insurance wellness programs: results of a US cross-sectional survey with multiple consumer health vignettes
Authors: Soliño-Fermández Diego , Ding Alexander , Bayro-Kaiser Esteban , Ding Eric L. 
Published: October 2019

Abstract
Background: The number of health-related wearable devices is growing but it is not clear if Americans are willing to adopt health insurance wellness programs based on wearables and the incentives with which they would be more willing to adopt.

Methods: In this cross-sectional study we used a survey methodology, usage vignettes and a dichotomous scale to examine U.S. residents’ willingness to adopt wearables (WTAW) in six use-cases where it was mandatory to use a wearable device and share the resulting data with a health insurance company. Each use-case was tested also for the influence of additional economic incentives on WTAW.

Results: A total of 997 Americans across 46 states participated in the study. Most of them were 25 to 34 years old (40.22%), 57.27% were female, and 74.52% were white. On average, 69.5% of the respondents were willing to adopt health-insurance use-cases based on wearable devices, though 77.8% of them were concerned about issues related to economic benefits, data privacy and to a lesser extent, technological accuracy. WTAW was 11-18% higher among consumers in use-cases involving health promotion and disease prevention. Furthermore, additional economic incentives combined with wearables increased WTAW overall. Notably, financial incentives involving providing healthcare credits, insurance premium discount, and/or wellness product discounts had particularly greater effectiveness for increasing WTAW in the consumer use-cases involving participation: for health promotion (RR=1.06 for financial incentive, 95% CI: 1.01-1.11; P=0.018); for personalized products and services (RR=1.11 for financial incentive, 95% CI: 1.01-1.21; P=0.018); and for automated underwriting discount at annual renewal (RR=1.28 for financial incentive, 95% CI: 1.20-1.37; P<0.001).

Conclusions:
Under the adequate economic, data privacy and technical conditions, 2 out of 3 Americans would be willing to adopt health insurance wellness programs based on wearable devices, particularly if they have benefits related to health promotion and disease prevention, and particularly with financial incentives.
Neonatal Mortality and Its Determinates in Public Hospitals of Gamo and Gofa Zones, Southern Ethiopia: Prospective Follow up Study
Authors: Mersha Abera , Bante Agegnehu , Shibiru Shitaye 
Published: October 2019

Abstract
Abstract
Background: The neonatal period is the most vulnerable time for child survival. The declines in the neonatal mortality rate have been slower than the post-neonatal under-five mortality rate in the majority of countries. This trend is also similar in Ethiopia, that neonatal mortality was high as compared to the post-neonatal mortality rate. A large proportion of neonatal deaths occur during the 48 hours after delivery. Different studies were conducted in assessing determinates for neonatal mortality but there is a need to assess the immediate postnatal (within two days following delivery) cause of neonatal mortality that the majority of deaths occurred at that time. So, this study is to fill those gaps of the aforementioned studies, in assessing the determinate factors affecting neonatal mortality in public hospitals of Gamo and Gofa Zones, Southern Ethiopia.
Methods: A prospective follow up study was conducted among 6,986 study participants from April 5, 2018, to March 5, 2019. All live births at the hospitals during the study period were included in this study. Data on causes of neonatal death were collected by using a structured verbal autopsy questionnaire. Data were entered into Epi data version 3.1 and exported to Stata version 15 for analysis. Crude and adjusted estimate β with 95%CI was calculated in the binary logistic regression model. The goodness of fit was tested by a log-likelihood ratio (LR). In this study P-value < 0.05 was considered to declare a result as a statistically significant association.
Results: In this study, neonatal mortality incidence ratio was 9.6 (95%CI: 7.5, 12.2) per 1000 live births. Age of the mother, number of antenatal care, hemorrhage, sex of the neonate, presentation, gestational age and birth weight were identified as the significant determinates for neonatal mortality. Prematurity, infection, and birth asphyxia were the most common causes of neonatal mortality cases.
Conclusions: This study indicated that a significant number of neonates died during the neonatal period. Both maternal and neonatal factors were identified. Therefore, early identification of obstetric complications and immediate interventions, strengthening the provision of quality antenatal and postnatal care services are recommended.
Keywords: Neonatal Mortality; Neonatal Deaths
The Use of Data Science to Analyse Physiology of Oxygen Delivery in the Extracorporeal Circulation
Authors: Lukaszewski Marceli , Lukaszewski Rafal , Kosiorowska Kinga , Jasinski Marek 
Published: October 2019

Abstract
Background Recent scientific reports brought into light a new concept of goal-directed perfusion (GDP) that aims to recreate physiological conditions in which the risk of end-organ malperfusion is minimalized. The aim of our study was to analyse patient’s interim physiology while on cardiopulmonary bypass based on the haemodynamic and tissue oxygen delivery measurements. We also aimed to create a universal formula that may help in the further implementation of the GDP concept. Methods We retrospectively analysed patients operated at Wroclaw University Hospital between June 2017 and December 2018. Since our observations provided a huge amount of data, including the patient's demographics, surgery details, and the perfusion-related data, the Data Science methodology was applied. Results A total of 272 (mean age 62.5±12.4, 74% male) cardiac surgery patients were included in the study. To study the relationship between haemodynamic and tissue oxygen parameters, the data for three different values of DO2i (280 ml/min/m2, 330 ml/min/m2 and 380ml/min/m2), were evaluated. Each set of those lines showed a descending function of CI in Hb concentration for the set DO2i. Conclusions Modern calculation tools make it possible to create a common data platform from a very large database. Using that methodology, we created models of haemodynamic compounds describing tissue oxygen delivery. The obtained unique patterns may both allow the adaptation of the flow in relation to the patient’s unique morphology that changes in time and contributes to the wider and safer implementation of tailored to individual patient’s needs perfusion strategy.
Phytoremediation effect of Medicago sativa colonized by Piriformospora indica in the phenanthrene and cadmium co-contaminated soil
Authors: Li Liang , Zhu Pengyue , Wang Xiaoyang , Zhang Zhenhua 
Published: October 2019

Abstract
Background:Coexistence of polycylic aromatic hydrocarbons (PAHs) and heavy metals deleteriously threatens the quality of environmental health. Few reports uncover the mechanism of inoculation plants with Piriformospora indica for remediating PAH-metal co-contaminated soil by analyzing the chemical speciations of contaminants. This study investigated the influence of inoculation Medicago sativa with Piriformospora indica to remediate phenanthrene (kind of PAHs), and cadmium (one of heavy metals) co-contaminated soil by analyzing the plant growth, physiological parameters and chemical speciation in rhizosphere and non-rhizosphere.

Results:The presence of P. indica significantly increased plants tolerance, Chlorophyll a, Chlorophyll b, maximum quantum efficiency of PSII photochemistry and electron transport rate values in phenanthrene and/or cadmium contaminated soil. P. indica inoculation in Medicago sativa root increased fluorescein diacetate activities in phenanthrene, cadmium and both of that co-contaminated soil, especially in non-rhizosphere. The presence of phenanthrene hindered the inoculated plant from accumulating cadmium to some extent; Whereas the presence of cadmium did not hinder the degradation of phenanthrene in both rhizosphere and non-rhizosphere after P. indica colonization. Although the poor bioavailability of cadmium in rhizosphere restricted the transportation into stem, P. indica colonization in plant efficiently increased cadmium accumulation in root in cadmium and phenanthrene co-contaminated soil.

Conclusions: In conclusion, the work provides the theoretical basis that Piriformospora indica combined with Medicago sativa contributed to the remediation of PAH-Metal co-contaminated soil.
Perceptions of pregnant women on reasons for late initiation of antenatal care: A qualitative interview study
Authors: Warri Denis , George Asha 
Published: October 2019

Abstract
Background: Antenatal care serves as a key entry point for a pregnant woman to receive a broad range of services and should be initiated at the onset of pregnancy. The aim of the study was to understand the reasons for late initiation of antenatal by pregnant women in Nkwen Baptist Health Center, Cameroon. Methods: The study applied purposive sampling to recruit eighteen pregnant women and three key informants for data collection through individual interviews. Pregnant women who initiated antenatal care after the first trimester were recruited during antenatal care clinics and interviewed in a room at the antenatal care unit. Key informants were midwives working at the antenatal care unit. Participation in the study was voluntary. Participants were explained the purpose of the study and signed a consent form if they were willing to participate in the research. Data was collected using an audio tape and analyzed using Thematic Coding Analysis. Results: Pregnant women place low value on early antenatal care due to the fact that they perceive pregnancy as a normal health condition or not a serious issue that requires seeking health care. Furthermore previous pregnancy outcomes that were positive regardless of accessing care made them less motivated to initiate antenatal care early. The booking system is perceived as user-unfriendly with overcrowded conditions, long waiting times and rudeness of some service providers. Cost of services and distance to health facilities with uncomfortable transport and poor road network were identified as perceived barriers. The absence of effective community health programmes, perceived lack of support from parents and spouses, fear of bewitchment and stigma due to cultural beliefs about early initiation of antenatal care were also identified as variables influencing late initiation. Conclusion: Pregnant women lack information on the purpose of early antenatal care. Health facility barriers as well as socio cultural beliefs also have significant influence on timing of antenatal care initiation. The government of Cameroon should strengthen the health system and implement activities that engage communities to improve timing of care seeking for antenatal care and thereby improve the maternal health status of women.
Application value of tissue tuberculosis antigen combined with Xpert MTB/RIF detection in differential diagnosis of intestinal tuberculosis and Crohn’s disease
Authors: fei baoying , zhou lin , zhang yu , Luo Linhe , Chen Yuanyuan 
Published: October 2019

Abstract
Abstract
Background: The purpose of this study was to evaluate the value of Xpert MTB/RIF detection and tuberculosis antigen detection of Mycobacterium tuberculosis (MTB) in intestinal tissues for differentiating intestinal tuberculosis (ITB) from Crohn’s disease (CD).
Materials and Methods: A total of 110 patients who were clinically diagnosed with CD or ITB were monitored. Several specimens of intestinal tissue from endoscopic biopsy or surgical excision were used for MTB culture and Xpert MTB/RIF detection, respectively. Four antigens (38KDa, ESAT-6, MPT64, Ag85 complex) of MTB in intestinal tissue were detected by immunohistochemistry.
Results: A total of 42 cases of intestinal tuberculosis and 46 cases of CD were included in the experimental analysis. Perianal lesions and longitudinal ulcers were more common in CD patients (p < 0.05), while caseous granuloma and annular ulcers were more common in ITB patients (P < 0.05). The positive rate of M. tuberculosis detected by Xpert MTB/RIF in intestinal tissue samples of ITB patients was 33.33%, which was significantly higher compared to CD patients (p < 0.05) and compared to acid-fast staining smears (9.52%) (p < 0.05). The positive MPT64 expression rate in patients with intestinal tuberculosis was 40.48%, which was significantly higher than that observed in CD patients, which was 19.56% (p<0.05).
Conclusions: The detection of Xpert MTB/RIF in intestinal tissue was conducive to the quick and early diagnosis of intestinal tuberculosis. Xpert MTB/RIF and MPT64 antigen in intestinal tissues had certain value in the differential diagnosis of intestinal tuberculosis and Crohn’s disease. The combination of these two methods could improve detection sensitivity.
MRI-based Radiomics of Rectal Cancer: Preoperative Assessment of the Pathological Features
Authors: Ma Xiaolu , Shen Fu , Jia Yan , Xia Yuwei , Li Qihua , Lu Jianping 
Published: October 2019

Abstract
[EXSCINDED]

Abstract

Background
This study aimed to evaluate the significance of MRI-based radiomics model derived from high-resolution T2-weighted images (T2WIs) in predicting tumor pathological features of rectal cancer.Methods

A total of 152 patients with rectal cancer who underwent surgery without any neoadjuvant therapy between March 2017 and September 2018 were included retrospectively. The patients were scanned using a 3-tesla magnetic resonance imaging, and high-resolution T2WIs were obtained. Lesions were delineated, and 1029 radiomics features were extracted. Least absolute shrinkage and selection operator was used to select features, and multilayer perceptron (MLP), logistic regression, support vector machine (SVM), decision tree, random forest (RF), and K-nearest neighbor were trained using fivefold cross-validation to build a prediction model. The diagnostic performance of the prediction models was assessed using the receiver operating characteristic curves.Results

A total of 1029 features were extracted, and 15, 11, and 11 features were selected to predict the degree of differentiation, T stage, and N stage, respectively. The best performance of the radiomics model for the degree of differentiation, T stage, and N stage was obtained by SVM [area under the curve (AUC), 0.862; 95% confidence interval (CI), 0.750–0.967; sensitivity, 83.3%; specificity, 85.0%], MLP (AUC, 0.809; 95% CI, 0.690–0.905; sensitivity, 76.2%; specificity, 74.1%), and RF (AUC, 0.809; 95% CI, 0.690–0.905; sensitivity, 76.2%; specificity, 74.1%).Conclusion

This study demonstrated that the high-resolution T2WI–based radiomics model could serve as pretreatment biomarkers in predicting pathological features of rectal cancer.
Factors associated with depression of the parents who lost their only child in western China city
Authors: Author) Chao Rong(Former Corresponding , Zheng Wei-Jun , Liu Tian-Li , Shen Shu-Hua , Fan Hong , Shen Wei-Wei , Author) Hui-Ling Yuan(New Corresponding 
Published: October 2019

Abstract
Background : The number of families who lost their only child is estimated to be 10 million by 2035. The parents who lost their only child are forced to endure psychological suffering and cope with elderly care problems alone. Long-term poor mental health can affect physical health and reduce the quality of life and well-being. Methods : 130 participants were selected using the method of combining stratified sampling with cluster sampling. The study used Geriatric Depression Scale (GDS) and adopted a generalized linear regression model to investigate the parents who lost their only child in Anshun city, Guizhou province, China, to comprehensively and systematically explore the depression status and it's influencing factors of the parents. Results : The parents who lost their only child of different self-rated health status ( P =0.004) and the number of chronic diseases ( P =0.001) had different GDS scores. European quality of life-5 dimensions (EQ-5D) score( P =0.019) and Social Support Rating Scale (SSRS) score ( P <0.001) were significantly associated with the depression of the parents who lost their only child. Conclusion : The parents who lost their only child is a high-risk group of depression, and targeted interventions should be carried out for them. The family doctor team should increase the frequency and content of serving them, and promptly manage their health. A diverse social support system should be built and consolidated for these parents.
Adolescent Lipid Screening and Associations with Socioeconomic Variables
Authors: Hudson Stephen E , Feigenbaum Matthew S. , Patil Nirav , Ding Elan , Ewing Alex , Trilk Jennifer L. 
Published: October 2019

Abstract
Background and Objective
The Southern region of the United States is home to substantial populations with obesity, dyslipidemia, and hypertriglyceridemia, while also housing a large percentage of America’s minority, rural, and low socioeconomic status (SES) peoples. Adult-onset cardiovascular disease (CVD) research may be informed by investigating associations(s) between late adolescent demographic variables and lipid values. Our objective was to investigate lipid parameter associations with college-age socioeconomic status, which may improve age-specific screening algorithms for management or prevention of adult-onset CVD.
Methods
Using an Analysis of Variance test and a general linear model, associations between gender, race/ethnicity, SES, and athletic participation on lipid parameters (VLDL-C, LDL-C, TG, TC, and HDL-C) were analyzed in 4423 private liberal arts college students enrolled in freshman-level wellness courses at Furman University in Greenville, SC. Comparative data were collected from an age-matched sample (National Health and Nutrition Examination Survey: NHANES 2003-2016). Our main outcomes were statistically significant relationships between any lipid values (TC, HDL-C, LDL-C, TG) and any demographic variables (gender, SES, ethnicity, athlete status).
Results
Males demonstrated lower TC and LDL-C, and higher HDL-C values. HDL-C was highest in athletes. African-American students demonstrated healthier VLDL-C, TG, and HDL-C values. With similar distributions, the age-matched NHANES comparison group showed unhealthier values in nearly all categories.
Conclusions
College students may have better lipid health than the general population. African-Americans may have seemingly healthier lipid values than age-matched individuals independent of athletic or college enrollment which has already been demonstrated in other studies. Future research should include SES relationships in lipid screening paradigms along with other appropriate risk factors for cardiovascular disease. Based on our comparative data, pediatric health providers and researchers may consider education as a potential protective factor against poor lipid health when considering lipid screening protocols for students.
Factors influencing adoption of facility-assisted delivery - a qualitative study of women and other stakeholders in a Maasai community in Ngorongoro District, Tanzania
Authors: Mosley Paul D , Saruni Kisiaya , Lenga Bernadetha 
Published: October 2019

Abstract
BACKGROUND: Tanzania’s One Plan II health sector program aims to increase facility deliveries from 50% to 80% from 2015-2020. Success is uneven among certain Maasai pastoralist women in Northern Tanzania who resist going to a facility for birth even after completing 4+ ANC visits. Ebiotishu Oondomonok Ongera (EbOO) is a program in Nainokanoka ward to promote facility-births through a care-group model using trained traditional birth attendants (TBAs) as facilitators. Results to date are promising but show a consistent gap between women completing ANC and those going to a facility for delivery. A qualitative study was conducted to understand psychosocial preferences, agency for decision-making, and access barriers that influence where a woman in the ward will deliver.
METHODS: In-depth interviews, focus group discussions and key-informant interviews were conducted with 24 pregnant and/or parous women, 24 TBAs, 3 nurse midwives at 3 health facilities, and 24 married men, living in Nainokanoka ward. Interviews and discussions were transcribed, translated, and analyzed thematically using a grounded theory approach.
RESULTS: Most women interviewed expressed preference for a home delivery with a TBA and even those who expressed agency and preference for a facility delivery usually had their last delivery at home attributed to unexpected labor. TBAs are engaged by husbands and play a significant influential role in deciding place of delivery. TBAs claim to support facility deliveries but in practice use them as a last resort and reported a significant trust gap based on a bad experience at a facility where women in labor were turned away.
CONCLUSIONS: EbOO project data and study results show a slow but steady change in norms around delivery preference in Nainokanoka ward. Gaps between expressed intention and practice, especially around ‘unexpected labor’ present opportunities to accelerate this process by promoting birth plans and perhaps constructing a maternity waiting house in the ward. Rebuilding trust between facility midwives, TBAs, and the community on the availability of health facility services, and increased sensitivity to women’s cultural preferences, could also close the gap between the number of women who are currently using facilities for ANC and those returning for delivery.
Fecal DNA Isolation and Degradation in Clam Cyclina sinensis: Noninvasive DNA Isolation for Conservation and Genetic Assessment
Authors: Zhang Min , Wei Min , Dong Zhiguo , Mao Shuang , Duan Haibao , Feng Senlei , Li Wenqian , Sun Zepeng , Li Jiawei , Yan Kanglu , Liu Hao , Meng Xueping , Ge Hongxing 
Published: October 2019

Abstract
Background

To avoid destructive sampling for conservation and genetic assessment, we isolated the DNA of clam Cyclina sinensis from their feces. DNA electrophoresis and PCR amplification were used to determine the quality of fecal DNA. And we analyzed the effects of different conditions on the degradation of feces and fecal DNA.Results

The clear fecal DNA bands were detected by electrophoresis, and PCR amplification using clam fecal DNA as template was effective and reliable, suggesting that clam feces can be used as an ideal material for noninvasive DNA isolation. In addition, by analyzing the effects of different environmental temperatures and soaking times on the degradation of feces and fecal DNA, we found that the optimum temperature was 4 °C. In 15 days, the feces maintained good texture, and the quality of fecal DNA was good. At 28 °C, the feces degraded in 5 days, and the quality of fecal DNA was poor.Conclusions

The clam feces can be used as an ideal material for noninvasive DNA isolation. Moreover, the quality of fecal DNA is negatively correlated with environmental temperature and soaking time.