bluuebunny/crossref_metadata_2025_split huggingface dataset:
A composite of clay, cement, and wood as natural support material for the immobilization of commercial titania (P25, P90, PC500, C-TiO2) towards photocatalytic phenol degradation
Authors: Morjène L. , Tasbihi M. , Schwarze M. , Schomäcker R. , Aloulou F. , Seffen M. 
Published: May 2020

AbstractDifferent types of commercial titania (P25, P90, PC500, and C-TiO2) were immobilized as single or mixed photocatalyst onto the surface of a natural support material made of cement, clay, and wood fibers. The successful immobilization was studied by different techniques showing a composite material with the mechanical properties of the support material and the photocatalytic behavior of the immobilized titania. The supported photocatalyst showed high mechanical stability and was applied to the photocatalytic degradation of phenol as a model pollutant under UV light irradiation. As the most active photocatalytic material, a mixture PC500 and P90 (comp-PC500/P90) was identified with an apparent pseudo first-order kinetic rate constant (kapp) of 0.010 min−1 at a degradation efficiency of 100%. The catalyst was used several times and showed minor loss in activity during four runs due to degradation intermediates adsorbed to the surface, shown by a color change from white to yellow.
Effects of Chlorine Dioxide on Oral Hygiene - A Systematic Review and Meta-analysis
Authors: Kerémi Beáta , Márta Katalin , Farkas Kornélia , Czumbel László M. , Tóth Barbara , Szakács Zsolt , Csupor Dezső , Czimmer József , Rumbus Zoltán , Révész Péter , Németh Adrienn , Gerber Gábor , Hegyi Péter , Varga Gábor 
Published: May 2020

Background:
Effective and selective oral rinses are required in the daily medical and dental practice.
Currently mouthwashes used have substantial side effects.

Objectives:
Our aim was to evaluate the efficacy of chlorine dioxide-containing mouthwashes in comparison with
other previously established mouth rinses in healthy adults using oral hygiene indices.

Methods:
This work was registered in PROSPERO (CRD42018099059) and carried out using multiple databases
and reported according to the PRISMA statement. The search terms used were “chlorine dioxide” AND “oral”,
and only randomised controlled trials (RCTs) were included. The primary outcome was the alteration of the
plaque index (PI), while the secondary outcomes were the gingival index (GI) and bacterial counts. For the risk of
bias assessment, the Cochrane Risk of Bias Tool was used. Statistical analysis for data heterogeneity was performed
by Q-value and I2-tests.

Results:
364 articles were found in the databases. After the selection process, only five RCTs were eligible for
meta-analysis. Data heterogeneity was low. There were no statistical differences in effectiveness between chlorine
dioxide and other effective mouth rinses in PI (0.720±0.119 vs 0.745±0.131; 95%; confidence intervals (CIs):
0.487-0.952 vs 0.489-1.001, respectively) and GI (0.712±0.130 vs 0.745±0.131; 95% CIs: 0.457–0.967 vs 0.489–
1.001, respectively) and also in bacterial counts.

Conclusion:
Chlorine dioxide reduces both plaque and gingival indices and bacterial counts in the oral cavity
similar to other routinely used oral rinses, however, the evidence supporting this outcome is very limited. Therefore,
further large scale RCTs are needed to decrease the risk of bias.
Exosome-based Tumor Therapy: Opportunities and Challenges
Authors: Li Chunmei , Hou Xiaoming , Zhang Peng , Li Juan , Liu Xiaoguang , Wang Yuping , Guan Quanlin , Zhou Yongning 
Published: May 2020

Background:Exosomes play an important role in transferring information among different cell types, as they transport materials from the cell membrane to the cytoplasm. They are involved not only in normal physiological functions, but also in the occurrence and development of a variety of diseases. Cancer is a major health problem affecting humans. Currently, exosomes are considered novel stars in tumor therapy.Objective:To present a review focusing on the role of exosomes in tumorigenesis and development and the possibility of treating tumors with exosome-targeted therapies or using exosomes as carriers.Methods:We reviewed literature related to the biological origin and function of exosomes and exosome-tumor relationship.Results:Exosomes are closely related to tumor immunity, angiogenesis, pre-metastasis microenvironment, chemoresistance, energy metabolism, etc. Tumor therapy involving the targeting of exosomes involves block the generation, secretion, uptake of exosomes, and elimination of circulating exosomes, and develop antitumor vaccines. Exosome as delivery vehicles can be loaded with chemotherapeutic drugs, therapeutic genes, and other therapeutic drugs to target cells. Prospects and challenges of exosome-based tumor therapy are also discussed.Conclusion:Exosomes are involved in multiple processes during tumor development and should be further studied as novel targets for cancer therapy.
Hydralazine-Induced ANCA Associated Vasculitis (AAV) Presenting with Pulmonary-Renal Syndrome (PRS): A Case Report with Literature Review
Authors: Doughem Karim , Battisha Ayman , Sheikh Omar , Konduru Lakshmi , Madoukh Bader , Al-Sadawi Mohammed , Shaikh Shakil 
Published: May 2020

:
Hydralazine, an arterial vasodilator, is a widely used medication for the management of
hypertension and heart failure, especially for patients who cannot tolerate the use of ACEIs or
ARBs. It is generally well-tolerated and has a safe profile in pregnancy. However, hydralazine can
induce immune-mediated side effects, such as hydralazine-induced lupus and less commonly hydralazine-
induced ANCA vasculitis. The latter most commonly affects the kidneys with or without
other organ involvement. There are several cases reported in the literature of hydralazine-induced
ANCA associated vasculitis (AAV) that have pulmonary manifestations, also known as hydralazine-
induced pulmonary-renal syndrome (PRS), a condition with a high risk of mortality. We are
reporting a case of Hydralazine-induced ANCA associated glomerulonephritis with severe diffuse
alveolar hemorrhage (DAH). In addition, we will review the current literature and discuss the importance
of prompt diagnosis and early management to decrease mortality and morbidity associated
with this serious condition.
The Role of Direct Oral Anticoagulant in Patients with Acute Coronary Syndrome on Single or Dual Antiplatelet Regime: Review of Opportunities and Challenges
Authors: Elnour Asim A. , Komócsi András , Kupó Péter , El Khidir Israa Y. , Zachariah Seeba , Sam Kishore G. , Asim Sahar , Sadeq Adel 
Published: May 2020

Background:
Despite the developments of single or dual antiplatelet therapy consisting
of aspirin and/or clopidogrel, prasugrel or ticagrelor, post-acute coronary syndrome a room for potential
improvement towards optimal prevention persist. The addition of a direct oral anticoagulant
to the antiplatelet treatment of patients with the acute coronary syndrome is clinically practiced in
cases where anticoagulation is indicated by high thromboembolic risk.

Objective:
The main objective of this review was to explore the role of supplementation with a direct
oral anticoagulant to antiplatelet (aspirin or P2Y12 inhibitor) in patients with the acute coronary
syndrome.

Methods:
We have searched the Medline for studies involving direct oral anticoagulant use in acute
coronary syndrome. We have reviewed specific relevant 9 meta-analyses between the years 2012 to
2019.

Results:
Our review of nine meta-analyses has revealed that the addition of direct oral anticoagulant
to antiplatelet therapy compared with antiplatelet alone was beneficial about the composite endpoints
of major ischemic events in patients with the acute coronary syndrome. Furthermore, the
combined regimen of single antiplatelet plus direct oral anticoagulant is as effective as the triple
regimen of dual antiplatelet plus direct oral anticoagulant and results in less bleeding.

Conclusion:
Cardiologists should balance the efficacy with a higher risk of bleeding with more
intensified DOAC therapy. Better risk characterization and timely adaptation of the regime to the
patient's need should be tested. Recurrent ischemic events and bleeding event risk scoring should
guide individualized treatment.
Chronic Suppurative Otitis Media: A Case Report
Authors: Yazdi M.M. Karimi , Ghalavand Zohreh , Yazdi Alireza K. , Kodori Mansoor , Taheri Marzieh , Tabriz Mahboobeh S. , Eslami Gita 
Published: May 2020

Background Context:
Chronic Suppurative Otitis Media (CSOM) is a common cause
of hearing impairment and disability. CSOM caused by Pseudomonas aeruginosa is usually
treated with topical ciprofloxacin and resistance to ciprofloxacin in CSOM isolates has rarely been
reported.

Case Presentation:
A 24-year-old male patient with CSOM due to p. aeruginosa was reported.
CSOM was prolonged for ten years and physician prescribed topical ciprofloxacin drops, pus suctioning
and ear pH alteration. The treatment wasn’t effective and the patient came back to the
clinic with relapse of suppurative otitis media. P. aeruginosa was isolated as the cause of CSOM
and the isolate was resistant to ciprofloxacin, aztreonam, imipenem, gentamicin, doripenem, cefepime,
levofloxacin, amikacin and susceptible to colistin and ceftazidime. There were two mutations
in gyrA and eight mutations were observed in nfxB genes. Finally, tympanomastoidectomy
was done.

Conclusion:
Usually topical antibiotics, especially ciprofloxacin, is effective against ear infections
but our case was different and the P. aeruginosa isolated from CSOM was resistant to most
of the antibiotics. One reason for CSOM recurrence might be surgery failure. The routine and primary
treatment for CSOM did not seem sufficient and tympanomastoidectomy is suggested to be
the best treatment approach for these patients.
The Combination of rTMS and Pharmacotherapy on In Vitro Models: A Mini-Review
Authors: Pourzitaki Chryssa , Dardalas Ioannis , Poutoglidou Frideriki , Kouvelas Dimitrios , Kimiskidis Vasilios K. 
Published: May 2020

Background:Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive brain stimulation technique that is being actively explored as a potential therapeutic modality in various neuropsychiatric disorders, such as depression, neuropathic pain, epilepsy, multiple sclerosis, and neurodegenerative disorders, including the Parkinson’s and Alzheimer’s disease. The Food and Drug Administration (FDA) approved rTMS for the treatment of major depression, migraine-associated headaches, and Obsessive Compulsive Disorder (OCD). The fact that a significant proportion of patients suffering from these disorders fail to respond to current pharmacological interventions indicates the need for alternative therapies like rTMS.Objective:The objective was to find and summarize all studies combining the use of rTMS and pharmacological interference in vitro, in order to facilitate future studies.Methods:The results of studies combining the use of rTMS with pharmacological interference in vitro were focused on. The PubMed database was searched using the terms “rTMS”, “repetitive”, “transcranial”, “magnetic”, “stimulation”, “in vitro”, “in vivo”, “cell cultures” untilMarch 2019 and 7 eligible studies were found.Results:Overall results show a synergistic effect of rTMS and pharmacotherapy in vitro with additive effectiveness, better prognosis, and superior potential management.Conclusion:The limited amount of knowledge denotes the need for additional in vitro studies on the combination of rTMS and pharmacotherapy, which could be extended to in vivo studies and ultimately help design clinical trials so as to improve the therapeutic management of patients with a wide array of neuropsychiatric disorders.
Een sensitieve snelle benoemtest voor woordvindproblemen bij patiënten met een laaggradig glioom
Authors: Ras Priscilla , Satoer Djaina , Rutten Geert-Jan , Vincent Arnaud , Visch-Brink Evy 
Published: May 2020

Patiënten met een laaggradig glioom (langzaam groeiende hersentumor) rapporteren vaak woordvindproblemen, terwijl deze met de huidig gebruikte benoemtests in de praktijk vaak niet geobjectiveerd worden. In deze studie worden de resultaten van een sensitieve snelle benoemtest (SBT) voor objecten besproken, toegepast bij deze patiëntengroep.
Via deze nieuwe test werden reactietijden verzameld van 18 patiënten met een vermeend laaggradig glioom en van 20 gezonde participanten. Om uit te sluiten dat bij glioompatiënten tragere reactietijden worden gevonden als gevolg van algehele cognitieve traagheid, zijn de resultaten van een test voor cognitieve snelheid (Trail Making Test-A, TMT-A) meegenomen in het onderzoek. De resultaten op de SBT zijn vergeleken met de resultaten op de klinisch veel gehanteerde Boston Naming Test (BNT) om zo de toegevoegde waarde van de SBT te kunnen evalueren. Tevens is het effect van woordfrequentie en Age of Acquisition (AoA) op de benoemtijden onderzocht. Glioompatiënten waren significant langzamer in het benoemen van de objecten dan de gezonde participanten. De tragere reactietijdenwerden niet verklaard door een algeheel tragere verwerkingssnelheid. Ook de BNT-scores konden de lagere reactietijden op de SBT niet verklaren. Een kwalitatieve vergelijking tussen de resultaten van de BNT en de SBT duidde op een hogere sensitiviteit van de SBT voor woordvindproblemen. In de groep gezonde participanten wordt een effect gevonden van woordfrequentie en AoA op de benoemsnelheden, in de patiëntengroep is echter geen effect van deze variabelen waar te nemen.
De resultaten laten een duidelijk verschil in benoemsnelheid zien tussen laaggradige glioompatiënten en gezonde participanten, terwijl patiënten zelden een afwijkende score behaalden op de BNT. Het lijkt zinvol om de SBT te gebruiken in de klinische praktijk, waarbij reactietijden als een belangrijk component meegenomen worden voor het diagnosticeren van woordvindproblemen bij glioompatiënten.
Effects of Stem Cutting Time and Height on Yield Components and Yield of Rice Ratun System (Oryza sativa L.)
Authors: Nuzul Vicky Silvia 
Published: May 2020

Ratun is the ability of the rice plant to regenerate new tillers after harvest, so it can be increased rice productivity. The aim of this research was to compare the yield components and yield between rice ratun with the parent rice, to analyze influence of stem cutting time and height on yield components and yield of rice ratun system and also to determine optimum cutting time and height for the yield components and yield of rice ratun. This research was heald in Pusat Inovasi Agroteknologi (PIAT) of Gadjah Mada University, Kalitirto, Berbah, Sleman, Yogyakarta on March to June 2017. The experiment used split-plot design with cutting time as the main plot and cutting height as sub plot with 3 blocks as replication. The cutting time consisted of 3 levels i.e. at harvest time, 7 days after harvest time, and 14 days after harvest time. Meanwhile, cutting height consisted of 4 levels i.e. 3 cm, 13 cm, 23 cm, and 33 cm above the ground.The research showed that the yield components and yield of rice ratun lower than the parent rice. Cutting time at harvest time, 7, 14 days after harvest time with the cutting height close to the ground increase yield component and yield of rice ratun but delay the generative phase. The highest yield components and yield of rice ratun achieved at harvest time cutting time with cutting height 3 cm above the ground.
Karakter Morfologi Akar dan Hasil Padi Ratun (<em>Oryza sativa</em> L.) pada Perbedaan Waktu dan Tinggi Pemotongan Tunggul Sisa Panen
Authors: Pratama Ananta Bayu , Indradewa Didik , Ambarwati Erlina 
Published: May 2020

Penelitian ini bertujuan untuk menentukan waktu dan tinggi pemotongan tunggul sisa panen yang optimal untuk mendukung pertumbuhan akar sehingga diperoleh daya hasil padi ratun maksimal. Percobaan lapangan disusun dalam Rancangan Acak Lengkap split plot 2 faktor dan 3 blok sebagai ulangan. Percobaan lapangan disusun dalam Rancangan Acak Kelompok Lengkap split plot 2 faktor dan 3 blok sebagai ulangan. Petak utama berupa waktu pemotongan tunggul, terdiri dari 3 taraf yaitu: saat panen (0 HSP), 7 hari setelah panen (7 HSP) dan 14 hari setelah panen (14 HSP). Anak petak berupa tinggi pemotongan tunggul, terdiri dari 4 taraf yaitu: 4 cm, 14 cm, 24 cm dan 34 cm. Variabel yang diamati berupa variabel morfologi akar dan hasil padi ratun. Data yang diperoleh dianalisis varians (ANOVA) dengan taraf kepercayaan 95%, dilanjutkan dengan uji polinomial orthogonal. Hubungan antar variabel pengamatan ditentukan dengan analisis korelasi. Hasil penelitian memberi informasi bahwa waktu pemotongan tunggul sisa panen hanya berpengaruh nyata terhadap diameter akar dengan waktu pemotongan terbaik 10 HSP yang menghasilkan diameter terbesar 0,89 mm, ketika dilakukan pemotongan tunggul setinggi 4 cm di atas permukaan tanah, namun tidak berpengaruh nyata terhadap sifat perakaran lainnya. Fase vegetatif yang paling lama (44 hari) dan produktivitas gabah yang paling tinggi (3,39 – 3,54 ton/ha) diperoleh bila tunggul dipotong setinggi 4 cm di atas permukaan tanah, namun perbedaan waktu pemotongan tunggul tidak berpengaruh nyata terhadap kedua variabel tersebut.
Serapan Hara N, P, K dan Hasil Biji Kedelai (<em>Glycine max </em>L. Merrill) pada Pemberian Bokashi Pelepah Pisang pada Tanah Pasir Pantai
Authors: Faozi Khavid , Yudono Prapto , Indradewa Didik , Ma'as Azwar 
Published: May 2020

The ability of several soybean varieties to absorb nutrient nitrogen, phosphorus and potassium (NPK) may be different in the new growing environment in coastal sands which are treated with bokashi made from banana stem. The aim of this study was to determine the NPK nutrient uptake and the responses of several soybean varieties to the level of banana stem bokashi application in coastal sand fields and to determine the optimum dose based on the yield of soybean seeds. The research was a field experiment conducted for 4 months from January until April 2017. Pot experiments in the field have been done in Samas coastal sands, Srigading Village, Sanden Sub-district, Bantul Regency, Special Region of Yogyakarta. The factorial experiment (4x12) was repeated 3 times, arranged in a complete randomized block design (RCBD). The first factor was dose banana stem bokashi including 0, 20, 40, and 60 t.ha-1; was tested on 12 soybean cultivars namely Anjasmoro, Argomulyo, Burangrang, Demas 1, Dena 1, Devon 1, Gamasugen 1, Gema, Gepak Ijo, Grobogan, Kaba, and Slamet. The observational data were analyzed by the variant analysis of the error rate of 5% and if significantly different was followed by DMRT 5% error level. The results showed that bokashi made from the banana stem can be used as a soil enhancer for coastal sandy soil, as well as providing nutrients for the growth of soybean plants. Nutrient uptake of N, P, K, plant dry weight, and seed yields of Anjasmoro varieties, Argomulyo, Demas 1, Devon 1, Gepak Ijo, Kaba and Slamet increased with the application of banana stem bokashi at doses of 20 and 40 t.ha-1, and decreases at bokashi doses reaching 60 t.ha-1. The optimum dose of bokashi made from banana stem doses equals 35.80 t.ha-1 with a maximum seed yield of 22.24 g.pot-1.
Tanggapan Teki terhadap Cekaman Kekeringan pada Berbagai Jenis Tanah
Authors: Paiman Paiman 
Published: May 2020

Teki (Cyperus rotundus) merupakan salah satu gulma dominan yang dapat tumbuh pada berbagai lahan pertanian dan berbagai jenis tanah pada kondisi air yang terbatas. Penelitian ini bertujuan untuk mengetahui pertumbuhan dan tanggapan teki terhadap cekaman kekeringan pada berbagai jenis tanah. Penelitian ini menggunakan percobaan pot yang disusun dalam rancangan tersarang dan diulang tiga kali. Faktor pertama yaitu jenis tanah yang terdiri atas 4 jenis yaitu tanah pasir pantai, alluvial, vulkanik dan grumusol. Faktor kedua yaitu cekaman kekeringan yang terdiri atas empat aras yaitu 25%, 50%, 75% dan 100% kapasitas lapang. Pengamatan meliputi tinggi gulma, panjang akar, jumlah umbi, luas daun, berat daun khas, rasio tajuk akar, kandungan prolin dan bobot kering gulma. Data hasil pengamatan dianalisis dengan analisis varian pada jenjang nyata 5%. Perbedaan antara perlakuan dianalisis dengan uji jarak berganda Duncan pada jenjang nyata 5%. Hasil penelitian menunjukkan pertumbuhan teki pada tanah grumusol memiliki tinggi lebih tinggi, akar lebih panjang, berat kering gulma lebih berat. Namun, teki yang tumbuh pada tanah pasir pantai memiliki jumlah umbi lebih banyak, daun lebih luas, rasio tajuk akar dan kandungan prolin lebih tinggi. Daun teki terluas ditemukan pada teki yang tumbuh pada tanah pasir pantai dan grumusol. Daun tertebal ditemukan pada tanah vulkanik. Teki yang tumbuh pada tanah dengan kadar air 25% kapasitas lapang mennujukkan tinggi dan panjang akar lebih pendek, daun lebih sempit, jumlah umbi lebih sedikit, bobot kering lebih rendah dan kandungan prolin lebih tinggi. Terjadi interaksi nyata antara jenis tanah dan cekaman kekeringan pada parameter kandungan prolin daun.
A paixão do Entusiasmo, em Diana Luz Pessoa de Barros. Elucubrações semio-patafísicas
Authors: Beividas Waldir 
Published: May 2020

Este texto de homenagem à nossa sempre mestre e guia teórico, Diana Luz Pessoa de Barros, pretende indicar breves pistas de estudos semióticos sobre a paixão do entusiasmo, tomando por inspiração a fina análise modal que Greimas fizera sobre a paixão da cólera, nos anos 1980, mas, desta feita, advertida quanto aos movimentos tensivos da semiótica de Zilberberg. A ideia foi mostrar que o estilo de pesquisa e de atitude teórico-acadêmica de Diana está balizado numa verdadeira paixão de entusiasmo, intenso, perante as ações de si própria e perante as ações do outro. Num segundo movimento do texto, a homenagem utiliza expedientes da ciência patafísica de Alfred Jarry para tecer certas elucubrações sobre onomástica, aplicada às quatro grandezas que definem o nome da homenageada: Diana, Luz, Pessoa, Barros.
THE USE OF DIGITAL TECHNOLOGY IN ESP: CURRENT PRACTICES AND SUGGESTIONS FOR ESP TEACHER EDUCATION
Authors: Kakoulli Constantinou Elis , Papadima-Sophocleous Salomi 
Published: May 2020

Developments in Information and Communication Technology (ICT) have transformed the way people communicate, interact and also the way they learn. ICT tools are widely used in language teaching and learning, and the benefits have been repeatedly expressed in literature. ESP is yet another area of language education that has been affected by these developments. Despite the fact that there are ESP practitioners who utilise technologies in their teaching, more research is needed in order to identify how widely technology tools are used in ESP, so that action is taken to empower practitioners and provide them with the help they need in order to integrate technology in their practices. This paper reports on the findings of a study conducted among 67 ESP practitioners from Tertiary Education in Greece and the Republic of Cyprus, the data of which were obtained through the use of an electronic questionnaire. The paper aims at examining the profiles of ESP practitioners in Greece and the Republic of Cyprus describing their use of technology (hardware and software) for the preparation and delivery of their courses. Furthermore, it outlines ESP practitioners’ views on the inclusion of a component on the use of technology in ESP teacher education. The paper concludes with suggestions regarding opportunities for professional development on issues related to the integration of ICT tools in ESP teaching and learning.