bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical Composition and Combinatory Antifungal Activities of Ammoides verticillata, Allium sativum and Curcuma longa Essential Oils Against Four Fungi Responsible for Tomato Diseases
Authors: Senouci Hanane , Benyelles Nassira G. , Dib Mohammed E.A. , Costa Jean , Muselli Alain 
Published: February 2020

Background:
Tomato is considered a model plant in genetics and is one of the most
economically important crops of all those that exist in the world. Several species of fungi are
reported on tomato fruit, causing damage both during cultivation and after harvest. Some of the
appropriate actions that could be initiated to resolve the problem are to develop and search for new
antimicrobial substances isolated from the bioactive natural products, such as essential oils.

Aim and Objective:
The aim of this work was to determine the chemical composition of essential
oils of Ammoides verticillata, Allium sativum and Curcuma longa, to evaluate their in-vitro antifungal
activities and in-vivo antifungal effect of essential oils to prevent the diseases caused by tomato.

Materials and Methods:
The essential oils obtained from aerial parts of plants were analyzed by
GC/MS and tested for their antifungal activities against Penicillium expansum, Fusarium solani,
Rhizopus stolonifer and Alternaria alternata using the radial growth technique method. The
effectiveness in-vivo of the association between Allium sativum and Curcuma longa essential oils
was also investigated on tomatoes inoculated by fungi.

Results:
The essential oil from A. verticilata was mainly composed of phenolic compounds
(54.4%), the A. sativum oil was mainly composed of sulfur compounds (91.5%) and C. longa oil
was dominated by oxygenated monoterpenes (82.0%). The obtained results in-vitro antifungal
revealed that individual essential oils of A. verticillata and A. sativum were more active than the
essential oil of C. longa against all screened microorganisms. An important antifungal effect of A.
sativum and C. longa essential oils blend was obtained against P. expansum (100%), F. solani
(95.2%), R. stolonifer (95.1%) and A. alternata (48.5%). Furthermore, A. sativum and C. longa
essential oils blends have demonstrated promising in-vivo antifungal activity to control infection of
tomato against P. expansum and R. stolonifer.

Conclusion:
A. sativum and C. longa essential oil blends can be used as a natural food preservative
and alternative to chemical fungicides to protect stored tomato against many phytopathogens.
Survival after Kidney Transplantation during Childhood and Adolescence
Authors: Francis Anna , Johnson David W. , Melk Anette , Foster Bethany J. , Blazek Katrina , Craig Jonathan C. , Wong Germaine 
Published: February 2020

Background and objectivesSurvival in pediatric kidney transplant recipients has improved over the past five decades, but changes in cause-specific mortality remain uncertain. The aim of this retrospective cohort study was to estimate the associations between transplant era and overall and cause-specific mortality for child and adolescent recipients of kidney transplants.Design, setting, participants, & measurementsData were obtained on all children and adolescents (aged <20 years) who received their first kidney transplant from 1970 to 2015 from the Australian and New Zealand Dialysis and Transplant Registry. Mortality rates were compared across eras using Cox regression, adjusted for confounders.ResultsA total of 1810 recipients (median age at transplantation 14 years, 58% male, 52% living donor) were followed for a median of 13.4 years. Of these, 431 (24%) died, 174 (40%) from cardiovascular causes, 74 (17%) from infection, 50 (12%) from cancer, and 133 (31%) from other causes. Survival rates improved over time, with 5-year survival rising from 85% for those first transplanted in 1970–1985 (95% confidence interval [95% CI], 81% to 88%) to 99% in 2005–2015 (95% CI, 98% to 100%). This was primarily because of reductions in deaths from cardiovascular causes (adjusted hazard ratio [aHR], 0.25; 95% CI, 0.08 to 0.68) and infections (aHR, 0.16; 95% CI, 0.04 to 0.70; both for 2005–2015 compared with 1970–1985). Compared with patients transplanted 1970–1985, mortality risk was 72% lower among those transplanted 2005–2015 (aHR, 0.28; 95% CI, 0.18 to 0.69), after adjusting for potential confounders.ConclusionsSurvival after pediatric kidney transplantation has improved considerably over the past four decades, predominantly because of marked reductions in cardiovascular- and infection-related deaths.
A mimese mediada como estratégia de midiatização da psicanálise no programa Terra Dois da TV Cultura-SP
Authors: Do Carmo Hebe Rios , Zanotti Carlos Alberto 
Published: February 2020

Este trabalho pretende demonstrar a estratégia de midiatização da psicanálise desenvolvida no programa Terra Dois da TV Cultura - SP a partir da convergência entre gêneros televisivos, identificada com o conceito de mimese
mediada. Foi aplicado o método de análise pragmática da narrativa, baseado em estudos sobre comunicação narrativa realizados por Motta (2013) e França (2004). Vozes narrativas dos campos da mediação e da representação compõem o formato criado para midiatizar a psicanálise na emissora voltada para programas de cunhos educativo, cultural e científico. Conclui-se que a mimese mediada apresenta características diferentes em cada um dos três blocos de Sinfonia sem fim, primeiro episódio da primeira temporada do seriado. O modelo inaugural do formato de Terra Dois fomenta ainda a perspectiva de diversificação de formatos em televisão para a veiculação de programas de cunhos científico, educativo e cultural.
A cone-beam computed tomographic evaluation of alveolar bone dimensional changes and the periodontal limits of mandibular incisor advancement in skeletal Class II patients
Authors: Matsumoto Kensuke , Sherrill-Mix Scott , Boucher Normand , Tanna Nipul 
Published: February 2020

ABSTRACT

Objectives
To evaluate the presence of dehiscences and changes in alveolar bone height and width in the area of the mandibular central incisors pre- and post-orthodontic treatment.

Materials and Methods
In 60 skeletal Class II patients, cone-beam computed tomographic (CBCT) images were obtained and the patients were divided into four groups based on the presence of dehiscences at pre- and post-orthodontic treatment. The alveolar bone height and width were measured on CBCT in cross section along the long axis of the teeth. Lateral cephalograms were analyzed.

Results
The changes in L1-NB and IMPA appeared to be correlated with vertical bone loss and dehiscence. Alveolar bone height appeared to follow a segmented relationship with these two variables, with changes below a threshold (L1-NB = 0.71 mm, IMPA = 3.02°) having relatively minimal or no effect on bone loss but with changes beyond the threshold correlated with extensive bone loss. Similarly, increases in L1-NB or IMPA correlated with decreases in alveolar bone width (L1-NB: −0.25 mm/mm, IMPA: −0.07 mm/°) and increased the probability of developing dehiscences, with an estimated 50% probability of vertical bone loss at a L1-NB change of 2.00 mm or, equivalently, an IMPA change of 8.02° was estimated.

Conclusions
When treating skeletal Class II patients, the limits of incisor proclination/protraction are less than previously thought. To prevent undesired periodontal outcomes, careful three-dimensional diagnosis is advisable. Furthermore, when excessive protrusion and/or proclination is planned, additional treatment modalities, including orthognathic surgery, tooth extraction, and corticotomy with bone graft, should be considered.
Simultaneous determination of warfarin and 7-hydroxywarfarin in rat plasma by HPLC-FLD
Authors: Zayed Aref , Babaresh Wahby M. , Darweesh Ruba S. , El-Elimat Tamam 
Published: February 2020

Abstract
In this study, high-performance liquid chromatography with fluorescence detection (HPLC-FLD) has been used for the first time, for direct determination of warfarin and its major metabolite, 7-hydroxywarfarin, in rat plasma. The simple and sensitive method was developed using Fortis® reversed-phase diphenyl column (150 × 4.6 mm, 3 μm) and a mobile phase composed of phosphate buffer (25 mmol L−1)/methanol/acetonitrile (70:20:10, V/V/V), adjusted to pH 7.4, at a flow rate of 0.8 mL min−1. The diphenyl chemistry of the stationary phase provided a unique selectivity for separating the structurally related aromatic analytes, warfarin and 7-hydroxywarfarin, allowing their successful quantification in the complex plasma matrix. The method was linear over the range 0.01–25 μg mL−1, for warfarin and 7-hydroxywarfarin, and was found to be accurate, precise and selective in accordance with US FDA guidance for bioanalytical method validation. The method was sensitive enough to quantify 0.01 μg mL−1 of warfarin and 7-hydroxywarfarin (LLOQ) using only 100 μL of plasma. The applicability of this method was demonstrated by analyzing samples obtained from rats after oral administration of a single warfarin dose, and studying warfarin and 7-hydroxywarfarin pharmacokinetics.
Advanced flow cell design for in vitro release testing of mucoadhesive buccal films
Authors: Grilc Blaž , Zdovc Jurij , Planinšek Odon 
Published: February 2020

Abstract
Films for buccal application are a slowly emerging new platform for drug delivery. There remains a lack of analytical techniques for the determination of in vitro active pharmaceutical ingredient release. The aim here was to develop an alternative method to the commonly used United States Pharmacopoeia (USP) 2 method, based on the flow-through cell. This system extends the release time and enables more detailed sample discrimination according to formulation. It could be used as a tool for in vivo prediction of drug release rates from buccal film formulations. The flow cell contains two chambers separated by a membrane through which the released active pharmaceutical ingredient is measured. Vital system variables and their effects on the release rate of the model active pharmaceutical ingredient are presented for formulations based on sodium alginate polymer. The method reflects the differences between films and is shown to be discriminatory for evaluation of buccal formulations.
A new finding of a uniquely large population of Anacamptis morio (Orchidaceae) on the Left-Bank Ukraine
Authors: Shevchyk Vasyl L. , Solomakha Igor V. , Shevchyk Oksana V. , Dvirna Tetyana S. , Solomakha Volodymyr A. , Shevchyk Taras V. , Fitsailo Tetyana V. 
Published: February 2020

Abstract
The paper presents the results of the research of local population of Anacamptis morio (L.) R. M. Bateman on the territory of the Left-Bank Ukraine. The size of this population was estimated at about 250-300 thousand individuals. The average density of individuals per 1 m2 is 12, while in terms of age structure, dominate individuals in the generative stage (70-75%). A. morio inhabits fresh, forest-meadow biotopes. Its populations are found in fresh eutrophic and moist mesotrophic meadows and in coastal floodplain forests. This species is a part of vegetation of the Koelerio-Corynephoretea and Molinio-Arrhenatheretea classes. Considering the characteristics of the investigated A. morio population and its habitat we assert that the studied territory is unique, valuable and perspective for the creation of a nature reserve.
The Quercetine Containing Drugs in Pharmacological Correction of Experimental Diabetes with Myocardial Injury
Authors: Stechyshyn Iryna , Pavliuk Bohdana 
Published: February 2020

AbstractBackground and aims:The prevalence of diabetes mellitus is becoming an epidemic. The diversity of etiological factors contributes to the fact that both types of diabetes mellitus occur among different age groups and among different segments of the population. Activation of various types of processes that lead to oxidative stress, endothelial dysfunction, the development of atherosclerotic changes, increases the risk of macro- and microvascular complications in diabetes mellitus.Material and methods: The experiments were performed on 172 white Wistar rats weighing 120–150 g. All animals were kept on a standard I. Horbachevsky Ternopil National Medical University (TNMU), vivarium diet. In our studies, for the first time was established a distinct cardioprotective effect of quercetin-containing drugs, Corvitin and Lipoflavon, for the purpose of normalizing disorders in type 1 and type 2 diabetes mellitus coupled with obesity, which opens wide opportunities for the introduction of these drugs into diabetic cardiomyopathy.Results:The results obtained are an experimental rationale for extending the indications of clinical use of Corvitin and Lipoflavon.Conclusion:Lipoflavon in the experimental type 1 and type 2 diabetes mellitus coupled with obesity significantly outperforms Corvitin in terms of TBA-active products and diene conjugates.
Assessment of Common Risk Factors and Lifestyle Habits Associated with Atherogenic Risk and Lipid-Lowering Therapy in Men with Type 2 Diabetes
Authors: Hadj-Benali Zakia , Diaf Mustapha , Khaled Méghit Boumediene 
Published: February 2020

Abstract

Background and aims: Our objective was to determine common risk factors and lifestyle habits associated with atherogenic risk and with the use of lipid-lowering therapy in men with type 2 diabetes.

Material and Methods: A comparative cross-sectional study was performed in the northwestern Algeria during eleven months on adult men patients with type 2 diabetes. Anthropometric parameters, blood pressures and lipid profile were evaluated. Data of common risk factors and lifestyle habits associated to atherosclerosis were compared between two groups according to the lipid lowering therapy use based on statins.

Results: 147 adult men patients with type 2 diabetes were involved in the study, 68 (46.26%) were under statins therapy and 79 (53.74%) were not. Significant associations with statins use were observed regarding the age group of 61-70 years (OR: 0.156 [0.043-0.570]; p=0.005), a salary of less than 30000 Algerian dinars (≈250.60$) (OR: 5.758 [1.299-25.512]; p=0.021), age of diabetes of 2-3 years (OR: 0.105 [0.013-0.867]; p=0.036) as well as with lipid ratios and body mass index (BMI). However, no significant associations were noted regarding the other studied parameters (marital status, educational level, occupation, salary, and family history, smoking status, alcohol consumption and sports practices) with lipid lowering therapy.

Conclusion: Age of patients, diabetes duration, lipid ratios and the low income of patients are the strongest factors associated with the use of lipid lowering therapy (statins). However, largest longitudinal studies are needed to determine whether modifiable lifestyle habits could influence the lipid lowering therapies prescription in diabetic patients over time.
Pharmacogenomics: introduction and use in clinical practice
Authors: Saunders Hollie , Harris Dana , Chirilă Răzvan M. 
Published: February 2020

Abstract
Pharmacogenomics describes the link between the genetic code and variations in drug response or adverse effects. It is rapidly gaining in both interest and accessibility. The knowledge of the gene-drug pairing for a wide range of medications will allow the clinician to select drugs with the best efficacy, appropriate dose and lowest likelihood of serious side effects.
In order to apply this knowledge, practitioners need to be familiar with the basic principles of pharmacodynamics and pharmacokinetics and how these relate to drug response. Once these are understood, so can be the genetic variations that lead to different phenotypes. Our review explains these concepts and uses examples of commonly prescribed medications and their gene pairings. At the present time, the Food and Drug Administration (FDA) guidelines remain sparse in regards to pharmacogenomic testing but, despite this, direct-to-consumer testing is widely available. In this context, we detail how to interpret a pharmacogenomic report, we review the indications for testing, as well as its limitations.
This information is a step ahead towards invidualized medicine, in the hope that tailoring medications and doses to an individual’s genetic make-up will predict a safe and effective response.
The speech act of threatening in German and Polish: Semantic and pragmatic aspects
Authors: Misiukajtis Joanna 
Published: February 2020

The major objectives of this study are to attempt to situate the speech act of threatening in the classification of speech acts and – on the basis of the linguistic and social factors conditioning the use of this speech act – to define the speech act of threatening for the purpose of analyzing the linguistic material. Additionally, the paper seeks to propose the main structure of the aforementioned speech act and a variety of factors conditioning its use in modern German and Polish.
The primary object of research in this work is the speech act of threatening analysed within the methodology of pragmalinguistics. The research material is composed of examples of the speech act of threatening in modern spoken Polish and German.
The analysis of the speech act of threatening presented in this study is an introduction and it will be further elaborated on in a monograph study of this topic.
Dihydromyricetin Attenuates Streptozotocin‐induced Liver Injury and Inflammation in Rats via Regulation of NF‐κB and AMPK Signaling Pathway
Authors: Chen Lei , Yao Maojun , Fan Xiaoyun , Lin Xiujun , Arroo Randolph , Silva Aline , Sungthong Bunleu , Dragan Simona , Paoli Paolo , Wang Shaoyun , Teng Hui , Xiao Jianbo 
Published: February 2020

Dihydromyricetin (DHM) dramatically improved the quality of life for Streptozotocin (STZ)‐induced diabetic rats and significantly increased the activity of antioxidant enzymes in the liver. Moreover, DHM successfully ameliorated diabetes‐induced liver damage by suppression of apoptosis in the liver, as indicated by the decreased levels of Bax and cleaved caspase‐3. In diabetic rats, the levels of tumor necrosis factor‐α and interleukin‐1β in the liver were significantly increased. However, the administration of DHM (100–400 mg/kg/day) for 6 weeks restored the cytokine levels to their normal values in a dose‐dependent manner in diabetic rats by the regulation of nuclear factor‐kappa B signaling pathway. In addition, DHM significantly induced 5′ AMP‐activated protein kinase (AMPK) phosphorylation and decreased MyD88, TLR4, p38, GSK‐3β protein expression levels in the liver of diabetic rats. In conclusion, DHM could improve STZ‐induced liver impairment by preventing oxidative stress, apoptosis, and inflammation.
So Your School is Becoming More Religiously Diverse...
Authors: Kumar Beth , Baker Drew , Milas Patrick 
Published: February 2020

Over the past decade, many Atla-member institutions have become increasingly religiously diverse. From larger actions like starting new interreligious programs or partnering with other institutions to smaller steps like changing branding and programming, many institutions have actively sought to become more ecumenical and/or interreligious and attract more students from religious traditions beyond the institutions’ particular historical traditions. Given this reality, how can librarians at these schools adapt to serve their increasingly religiously diverse students better? What do librarians whose institutions are moving in more ecumenical or interreligious directions need to consider? From collection development to reference and instruction, this panel reflected on this topic as the panelists raised important questions and provided helpful, practical advice based on their experiences at their institutions.
All three panelists are part of the World Religions Interest Group (WRIG) of Atla. More information on WRIG is at https://www.atla.com/learning-engagement/groups/ig/wrig/
Sistem Informasi Akuntansi Pemesanan dan Pembayaran (Ordering and Billing) Makanan dan Minuman Berbasis Android Pada RM. Ayam Goreng “Padamara” Purbalingga
Authors: Marifati Imam Soleh , Maarif Vadlya 
Published: February 2020

Abstract - Ordering and billing transactions of food and beverages in a restaurant business are in the revenue cycle. Transactions in the revenue cycle have an important role for the company because from this transaction the company gets cash income. The use of information technology to support the transaction process can increase the effectiveness of the transaction process. Transactions can be processed quickly and accurately. Restaurant business can use accounting information systems to improve the effectiveness and efficiency of transaction processes in the revenue cycle. A computer-based accounting information system is needed in processing transactions. In this study, the authors developed the application of accounting information systems to process transactions in the revenue cycle for restaurant business activities. This application processes transaction data starting from ordering, payment and making revenue reports from restaurant business activities.
Keywords: Order, Billing, Accounting Information System
Implementasi Metode SAW Pada Sistem Informasi Penyeleksian Peserta WUBI
Authors: Prasetya Erawan , Alawiyah Tuti , Ratningsih Ratningsih 
Published: February 2020

Abstract - The BI Entrepreneurship Program is an annual Bank Indonesia Tasikmalaya Program with the aim of producing entrepreneurs who are quality and sustainable with a lot of knowledge from starting their respective product introductions to the Promotion Strategy. Participants who qualify for WUBI Selection will get funding from BI as the business capital of the participants. In the WUBI Participant Selection Implementation they still use a conventional system so that the WUBI Participant Selection Process takes a long time so it is not effective and efficient. Existing computerization systems that have not been computerized often cause difficulties in finding participant data because they still use files or documents. Solution to the problem in the selection of WUBI Participants, the authors designed the WUBI Participant Participation System based on the website and the Selection of Participants using the SAW Method using four criteria, namely Business Survey, Innovation, Creativity and Financial Managerial as supporting criteria for WUBI Participant Selection.
Keywords: SAW, selection information system, WUBI
PEMBELAJARAN MATEMATIKA BERBANTUAN ANDROID UNTUK MENINGKATKAN PEMAHAMAN KONSEP MATEMATIS
Authors: Meliyana Meliyana , Rahmatudin Jajang , Hidayat Rifqi 
Published: February 2020

Penelitian ini menguji akan kemampuaan pemahaman konsep matematis siswa SMK setelah diterapakannya pembelajaran matematika berbantuan android (aplikasi geogebra). Penelitian ini didasari oleh rendahnya pemahaman konsep matematis siswa SMK dalam pembelajaran matematika. Tujuan Penelitian ini adalah untuk mengetahui perbedaan serta peningkatan pemahamana konsep matematis siswa SMK yang pembelajaran matematikanya berbantuan android (aplikasi geogebra) dengan siswa yang pembelajaran matematikanya secara konvensional. Penelitian ini merupakan penelitian Quasi Experimental Design dengan bentuk Nonequivalent Control Group Design. Populasi dalam penelitian ini adalah kelas X SMK Plus Al-Hilal Arjawinangun Kabupaten Cirebon Tahun Pelajaran 2019/2020. Sampel penelitian melibatkan 30 siswa kelas X Teknik Komputer dan Jaringan (TKJ) sebagai kelas eksperimen dan 30 siswa kelas X Perbankan (PRB) sebagai kelas kontrol. Sampel dalam penelitian ini menggunakan teknik sampling purposive. Instrumen yang digunakan dalam penelitian ini berupa tes kemampuan pemahaman konsep matematis, lembar observasi guru dan siswa. Analisis data dilakukan secara kuantitatif menggunakan uji Independent Samples T-Test dan uji Mann-Whiney U (nonparametrik). Hasil penelitian ini menunjukan bahwa: (1) Kemampuan pemahaman konsep matematis siswa yang pembelajarannya berbantuan android (aplikasi geogebra) lebih baik daripada siswa yang pembelajarannya secara konvensional; (2) Peningkatan pemahamana konsep matematis siswa yang pembelajarannya berbantuan android (aplikasi geogebra) lebih baik daripada siswa yang pembelajarannya secara konvensional.