bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two replications of Raymond, Shapiro, and Arnell (1992), The Attentional Blink
Authors: Grassi Massimo , Crotti Camilla , Giofrè David , Boedker Ingrid , Toffalini Enrico 
Published: August 2020

AbstractIn order to improve the trustworthiness of our science, several new research practices have been suggested, including preregistration, large statistical power, availability of research data and materials, new statistical standards, and the replication of experiments. We conducted a replication project on an original phenomenon that was discovered more than 25 years ago, namely the attentional blink (Raymond, Shapiro, & Arnell, Human Perception and Performance, 18(3), 849–860, 1992), which has been conceptually replicated hundreds of times with major variations. Here, we ran two identical experiments, adopting the new practices and closely reproducing the original experiment. The two experiments were run by different research groups in different countries and laboratories with different participants. Experiment 1 shared remarkable similarities (in magnitude and duration of the effect) with the original study, but also some differences (the overall accuracy of participants, the timing of the effect, and lag-1 sparing). Experts interviewed to evaluate our results stressed the similarities rather than the differences. Experiment 2 replicated nearly identically the results observed in Experiment 1. These findings show that the adoption of new research practices improves the replicability of experimental research and opens the door for a quantitative and direct comparison of the results collected across different laboratories and countries.
TRATAMENTO CONSERVADOR DE RÂNULA EM CRIANÇA: UM RELATO DE CASO
Authors: Lemes Weberson Dantas , Amaral Lara Ricardo Ferreira , Felga Cláudio Souto França , Martins Allisson Filipe Lopes 
Published: August 2020

Introdução: A Rânula é uma lesão de característica cística localizada em soalho de boca, acontece devidoao extravasamento de muco das glândulas sublingual e submandibular. A lesão é flutuante e varia de cordo azulado ao rósea e correspondendo a variação da mucocele. As principais causas são traumas eobstrução de ductos salivares. Ela pode ser indolor, ter remissão espontânea e seu tratamento pode serconservador ou não, no entanto tratamentos agressivos, como a exérese da lesão e da glândula afetada,são descritos. Objetivo: relatar um caso de rânula em paciente de dez anos, tratado com sucesso a partirda marsupialização. Relato do caso: Paciente do sexo feminino, dez anos de idade, compareceu aoconsultório com queixa de “caroço debaixo da língua”. A responsável relatou aparecimento de bolha emsoalho de boca, assintomático, com um mês de evolução. Foi relatado histórico de câncer de língua nafamília (tio). Ao exame clínico foi observada bolha de aproximadamente 2cm, de aspecto translúcido,consistência flutuante localizada soalho de boca posterior do lado esquerdo. A hipótese de diagnóstico foide rânula e uma abordagem não cirúrgica foi proposta, por meio da utilização do uso de sialogogos,aumento da ingestão de água e massagem da glândula. No entanto foi necessária uma abordagemcirúrgica, levando em consideração o tamanho da lesão, a idade da paciente e o insucesso com otratamento não cirúrgico, foi realizada a marsupialização. Considerações Finais: A marsupialização deveser levada em consideração, pois além de ser menos invasiva possibilita ao paciente uma melhor qualidadede vida.
Palavras-chaves: rânula; mucocele; glândulas salivares
Computational Insight into Diatomic Molecules as Probes to Measure the Variation of the Proton-to-electron Mass Ratio
Authors: Syme Anna-Maree , McKemmish Laura K. 
Published: August 2020

Abstract
Astrophysical molecular spectroscopy is an important means of searching for new physics through probing the variation of the proton-to-electron mass ratio, μ. New molecular probes could provide tighter constraints on the variation of μ and better direction for theories of new physics. Here we summarize our previous paper for astronomers, highlighting the importance of accurate estimates of peak molecular abundance and temperature as well as spectral resolution and sensitivity of telescopes in different regions of the electromagnetic spectrum. While none of the 11 astrophysical diatomic molecules we investigated showed enhanced sensitive rovibronic transitions at observable intensities for astrophysical environments, we have gained a better understanding of the factors that contribute to high sensitivities. From our results, CN, CP, SiN and SiC have shown the most promise of all astrophysical diatomic molecules for further investigation, with further work currently being done on CN.
Comparing the 2009 and 1997 World Health Organization dengue case classifications in a large cohort of South Asian patients
Authors: Jayarajah Umesh , Dissanayake Upul , Abeysuriya Visula , De Silva Pradeep K , Jayawardena Priyankara , Kulatunga Aruna , Fernando Harshini , Madarasinghe Manohari , Hapugoda Damayanthi , Perera Lakshika , Kannangara Vibhavee , Udayangani Champika , Peiris Ranga , Faizer Shuaib , Yasawardene Pamodh , De Mel Sanjay , De Zoysa Ishan , Seneviratne Suranjith L 
Published: August 2020

Introduction: Due to the shortcomings in the 1997-World Health Organisation (WHO) dengue case classification (DCC), a revised classification was proposed in 2009. This study was aimed to assess the clinical usefulness of the two classifications during a large dengue epidemic.
Methodology: Clinical data of dengue patients admitted to selected units at National Hospital of Sri Lanka, Panadura Base Hospital and Nawaloka Hospital Colombo between June and August 2017 were collected prospectively. Cases were classified using the 1997 and 2009 WHO DCCs.
Results: 1,878 patients [adult = 1,573 (83.8%)] were studied. Based on 1997-WHO-DCC-DF (Dengue Fever): 1,316 (70.1%), DHF (Dengue Haemorrhagic Fever) -1: 468 (24.9%), DHF-2: 86 (4.6%) and DHF-3: 8 (0.4%). Based on 2009-WHO-DCC–Dengue with warning signs (WS): 1647 (87.7%), Dengue without WS: 231 (12.3%) and severe dengue (SD): 41 (2.18%). A total of 1,088 (82.7%) DF and 559 (99.5%) DHF patients developed WS. Of those without WS, 228 (17.3%) were DF patients and 3 (0.5%) were DHF patients. Three (0.23%) DF and 38 (6.76%) DHF patients had SD. All SD patients had WS. The level of agreement between the two systems of classification was poor (Kappa = - 0.035, p < 0.001).
Conclusions: The 2009-WHO-DCC was more useful than 1997-WHO-DCC in predicting dengue disease severity as few DF patients also had SD. Furthermore, the presence of WS identified patients with SD. However, the 2009-WHO-DCC may not suit the resource limited countries as WS are non-specific, and lack of diagnostic tests can result in case overload.
Transmission dynamics of Covid-19 in Italy, Germany and Turkey considering social distancing, testing and quarantine
Authors: Gul Serdar , Tuncay Kagan , Binici Baris , Aydin Beyazit Bestami 
Published: August 2020

Introduction: There are significant differences in the active cases and fatality rates of Covid-19 for different European countries.
Methodology: The present study employs Monte Carlo based transmission growth simulations for Italy, Germany and Turkey. The probabilities of transmission at home, work and social networks and the number of initial cases have been calibrated to match the basic reproduction number and the reported fatality curves. Parametric studies were conducted to observe the effect of social distancing, work closure, testing and quarantine of the family and colleagues of positively tested individuals.
Results: It is observed that estimates of the number of initial cases in Italy compared to Turkey and Germany are higher. Turkey will probably experience about 30% less number of fatalities than Germany due its smaller elderly population. If social distancing and work contacts are limited to 25% of daily routines, Germany and Turkey may limit the number of fatalities to a few thousands as the reproduction number decreases to about 1.3 from 2.8. Random testing may reduce the number of fatalities by 10% upon testing least 5/1000 of the population. Quarantining of family and workmates of positively tested individuals may reduce the total number of fatalities by about 50%.
Conclusions: The fatality rate of Covid-19 is estimated to be about 1.5% based on the simulation results. This may further be reduced by limiting the number of non-family contacts to two, conducting tests more than 0.5% of the population and immediate quarantine of the contacts for positively tested individuals.
« Je ne veux pas organiser les femmes ». Travail social féministe et pouvoir d’agir
Authors: Cardoso Auréline 
Published: August 2020

S’appuyant sur une ethnographie de trois mois menée au sein d’une association féministe gérant un service d’accueil de femmes victimes de violences, cet article propose d’interroger le potentiel transformateur du travail social féministe mis en œuvre dans cette association. Il s’intéresse aux processus d’ empowerment et de conscientisation que les professionnelles de l’association tentent d’impulser chez les femmes qu’elles accueillent, ces dernières étant le plus souvent éloignées des idées et du militantisme féministe. Une première partie présente le travail social féministe, en s’attachant à mettre en lumière son inscription dans le travail social comme son opposition à certaines de ses pratiques. Les deux parties suivantes, plus ethnographiques, donnent à voir le travail de conscientisation en direction des femmes accueillies, et les effets de celui-ci en termes de pouvoir d’agir individuel. Il s’agit de montrer comment certaines valeurs du travail social féministe peuvent entrer en contradiction avec la mise en œuvre d’un réel travail de mobilisation des femmes accueillies, qui nécessiterait pour les professionnelles d’adopter une posture « d’avant-garde » qu’elles rejettent.
RIPK3–MLKL–Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α
Authors: Wang Xiaoliang , Gessier Francois , Perozzo Remo , Stojkov Darko , Hosseini Aref , Amirshahrokhi Keyvan , Kuchen Stefan , Yousefi Shida , Lötscher Pius , Simon Hans-Uwe 
Published: August 2020

Abstract
Cytokine-primed neutrophils can undergo a nonapoptotic type of cell death using components of the necroptotic pathway, including receptor-interacting protein kinase-3 (RIPK3), mixed lineage kinase-like (MLKL) and NADPH oxidase. In this report, we provide evidence for a potential role of serine proteases in CD44-mediated necroptotic death of GM-CSF–primed human neutrophils. Specifically, we observed that several inhibitors known to block the enzymatic function of fibroblast activation protein-α (FAP-α) were able to block CD44-mediated reactive oxygen species production and cell death, but not FAS receptor–mediated apoptosis. To understand how FAP-α is involved in this nonapoptotic death pathway, we performed immunoblotting experiments in the presence and absence of inhibitors of RIPK3, MLKL, p38 MAPK, PI3K, and FAP-α. The results of these experiments suggested that FAP-α is active in parallel with RIPK3, MLKL, and p38 MAPK activation but proximal to PI3K and NADPH oxidase activation. Interestingly, neutrophils isolated from the joints of patients suffering from rheumatoid arthritis underwent a GM-CSF–independent necroptosis following CD44 ligation; this effect was also blocked by both FAP-α and MLKL inhibitors. Taken together, our evidence shows that the RIPK3–MLKL pathway activates NADPH oxidase but requires, in addition to p38 MAPK and PI3K, a serine protease activity, whereby FAP-α is the most likely candidate. Thus, FAP-α could be a potential drug target in neutrophilic inflammatory responses to avoid exaggerated nonapoptotic neutrophil death, leading to tissue damage.
Diversity Outbred Mice Reveal the Quantitative Trait Locus and Regulatory Cells of HER2 Immunity
Authors: Wei Wei-Zen , Gibson Heather M. , Jacob Jennifer B. , Frelinger Jeffrey A. , Berzofsky Jay A. , Maeng Hoyoung , Dyson Gregory , Reyes Joyce D. , Pilon-Thomas Shari , Ratner Stuart , Wei Kuang-Chung 
Published: August 2020

Abstract
The genetic basis and mechanisms of disparate antitumor immune response was investigated in Diversity Outbred (DO) F1 mice that express human HER2. DO mouse stock samples nearly the entire genetic repertoire of the species. We crossed DO mice with syngeneic HER2 transgenic mice to study the genetics of an anti-self HER2 response in a healthy outbred population. Anti-HER2 IgG was induced by Ad/E2TM or naked pE2TM, both encoding HER2 extracellular and transmembrane domains. The response of DO F1 HER2 transgenic mice was remarkably variable. Still, immune sera inhibited HER2+ SKBR3 cell survival in a dose-dependent fashion. Using DO quantitative trait locus (QTL) analysis, we mapped the QTL that influences both total IgG and IgG2(a/b/c) Ab response to either Ad/E2TM or pE2TM. QTL from these four datasets identified a region in chromosome 17 that was responsible for regulating the response. A/J and NOD segments of genes in this region drove elevated HER2 Ig levels. This region is rich in MHC-IB genes, several of which interact with inhibitory receptors of NK cells. (B6xA/J)F1 and (B6xNOD)F1 HER2 transgenic mice received Ad/E2TM after NK cell depletion, and they produced less HER2 IgG, demonstrating positive regulatory function of NK cells. Depletion of regulatory T cells enhanced response. Using DO QTL analysis, we show that MHC-IB reactive NK cells exert positive influence on the immunity, countering negative regulation by regulatory T cells. This new, to our knowledge, DO F1 platform is a powerful tool for revealing novel immune regulatory mechanisms and for testing new interventional strategies.
Debenture as Alternate Scheme of Raising Investment Fund and Its Prospects under Ethiopian Company Law
Authors: Anebo Lantera Nadew 
Published: August 2020

With a view to attracting investors, the Government of Ethiopia has offered a variety of incentives and financing schemes. However, the incentives or loan options can be inadequate, susceptible to corrupt practices and inaccessible to many business undertakings. This article examines other possible options of raising investment fund privately from the general public by issuing debt security (debenture). Instead of looking for hand outs of governments or sole reliance on bank loan, investors can raise investment fund from the general public –even beyond national borders– by offering debenture bonds for public subscription. A debenture is debt security that entitles its holder to collect periodic interest until the loan is paid back. Compared to bank loans, raising investment fund through the instrumentality of debentures is more advantageous. The rate of interest, the volume of loan needed for running business, and the time for repayment can be determined by investors. Moreover, the loan is not generally subject to collateral. This article highlights the nature, form, and class of debenture under Ethiopian law, and discusses the legal requirements for the issuance of debenture, the amount of money that can be raised by issuing debentures, the status of debentures in Ethiopia, and legal safeguards for repayment of the loan.
Key terms
Debenture, Bond, Investor, Floating charge, Creditor, Debtor, Ethiopia
Literatura e Arte no ensino de Ciências: a formação de professores para alunos com deficiências visuais no Ensino Fundamental
Authors: Barbosa-Lima Maria da Conceição De Almeida 
Published: August 2020

Trata o presente trabalho de uma proposta de formação de professores inclusivistas, ou seja, aqueles que acreditam que alunos sem quaisquer problemas detectados e alunos com quaisquer deficiências, possam estudar em escolas regulares. Fazemos uma conjugação entre Arte, especialmente a Literatura, no formato de histórias infantis para o ensino de tópicos elementares de Física nos anos iniciais de escolarização. Consideramos essencial o ensino equânime dos alunos considerados sem problemas aparentes e aqueles com deficiência visual. Apresentamos nossas atuações anteriores no campo de estudo da conjugação entre Literatura e Física e Arte Plástica e Física, como exercícios para chegarmos ao ponto em que hoje nos encontramos. Estamos certos de que os professores necessitam exercitar sua imaginação e criatividade, tanto para elaborar as histórias, quanto para avaliar sua compreensão, no que diz respeito ao tópico em pauta. Relatamos o que esperamos da formação de licenciandos de nossa Universidade e os tópicos do Manifesto CiênciArte, que seguimos em nossa prática, tanto na formação, quanto em nossa atuação profissional.
Paisajes culturales y proyecto territorial: un balance de treinta años de experiencia
Authors: Sabaté Bel Joaquín , Benito del Pozo Paz 
Published: August 2020

En este artículo se desarrolla una valoración sintética de la consideración que han ido ganando los “paisajes del trabajo” en España durante los últimos treinta años, del marco en el que se han desenvuelto y de las principales intervenciones sobre los mismos. Se quiere destacar, en primer lugar, cómo algunos agentes han construido un “estado de opinión”, contribuyendo a un creciente interés por dicho patrimonio. Esto incluye a profesionales,departamentos universitarios y centros de investigación, pero asimismo se considera la labor de difusión a través de publicaciones, congresos y museos. Del marco en el que se han desenvuelto cabe referirse a algunas normas que han tenido una clara incidencia en este campo.
Finalmente se pretende verificar como en bien pocos años hemos ido desarrollando instrumentos de intervención cada vez más complejos, comprometidos y de mayor escala, desde los primeros inventarios, catálogos y trabajos de documentación; a las intervenciones aisladas, de recuperación y reutilización de edificios singulares; a los planes y programas donde se integra el patrimonio industrial (del trabajo en general) en propuestas coordinadas de mayor ambición y finalmente, a proyectos territoriales, donde dicho patrimonio constituye el eje de la intervención y puede devenir motor de desarrollo local.
En el límite cabría aspirar a que el patrimonio industrial, el del trabajo en general, juegue un papel equivalente en cualquier proyecto o plan territorial, al que ha alcanzado el patrimonio natural; que cultura y natura se conviertan en ejes de reflexión y medida de nuestras intervenciones sobre el territorio.
Cuenca del Cebollatí: nuestro territorio, un proyecto compartido: formulación de las bases de ordenamiento territorial y desarrollo sostenible
Authors: Martínez Susana , Benevides Alessandra , Falkenstein Alejandro , Varela Alma , Saravia Matilde 
Published: August 2020

Este documento presenta los resultados de un trabajo interdisciplinar de carácter analítico-propositivo realizado en el ámbito de la Maestría de Ordenamiento Territorial y Desarrollo Urbano (Facultad de Arquitectura,
Universidad de la República ). Relata una experiencia que coordinó esfuerzos y
acciones entre el ámbito académico, el gobierno nacional y los gobiernos
locales.
El trabajo toma como unidad de estudio y propuesta el territorio de la Cuenca
del Río Cebollatí, y tiene como objetivo formular las bases de ordenamiento
territorial que habiliten la preservación de los recursos naturales y culturales de
la zona, así como la revalorización de los elementos de identidad, sus tradiciones. Está desarrollado en el marco de la Ley de Ordenamiento territorial y Desarrollo Sostenible que definió nuevas pautas y roles institucionales en la temática. En este contexto, la construcción de políticas de ordenamiento territorial para la Cuenca implicó un proceso participativo, como una sacudida de tradiciones, voces y sensaciones, novedoso en Uruguay.
This paper presents the results of an interdisciplinary analytical-propositional
work that was made within the scope of Planning and Urban Development Master Studies (School of Architecture, Udelar). It shows a coordinated experience between the academia, national and local governments.
The work takes as its unit of analysis and proposal the Cebollatí Basin, and its
aims is to formulate the planning bases that enables the preservation of its
natural and cultural resources as well as the appreciation of its identity and
traditions. The work is developed within the scope of Planning and Sustainable
Development Law that defines new guidelines and institutional roles in this subject. In this context, the construction of planning policies for the Basin involved a participatory process, like a jolt of traditions, voices and feelings,
which is new in Uruguay.
Proyecto García: construcción de la ciudad de la costa
Authors: Secco Terra Gabriela 
Published: August 2020

Se analiza el proceso de urbanización de la Ciudad de la Costa, complejo y
creciente territorio metropolitano montevideano, que a la vez es la segunda
ciudad más importante de Uruguay. Entendido siempre como un proceso
espontáneo y sin planificación de formación del territorio, se sugiere una mirada
al mismo como un proyecto de suelo global que se realiza en un siglo, donde la
agrimensura y la forestación adquieren crucial importancia. El proyecto se inicia
con la adquisición de un gran campo por parte de un empresario que comienza
a utilizar la forestación como instrumento de recuperación y cualificación de tierras pantanosas. Una primera partición de la tierra marca las principales trazas en el territorio, y un sucesivo proceso de fraccionamiento del suelo rural con visión urbanizadora, primero motivado por un reparto equitativo entre los descendientes de Doroteo García, pero luego por un proyecto urbanizador basado en la cultura de sol y playa y la especulación inmobiliaria, define los principales componentes de este proyecto.
This article analyses the urbanization process of the Ciudad de la Costa, a
complex and growing metropolitan territory in Montevideo and the second largest city of Uruguay. Always understood as a spontaneous configuration process and an unplanned territory, a view of a global land project is suggested, completed in one century and in which the surveying and afforestation acquires crucial importance. The project begins with the acquisition of a large field by a businessman who starts using forestry as a tool for recovery and qualification of
wetlands. A first land partition defines the main traces in the territory, and it is
followed by a process of rural land fragmentation with an urban vision: first
motivated by an equal distribution among the descendants of Doroteo Garcia, but then by an urbanizing project based in the sun and beach culture and real estate speculation. This defines the main components of this project.