THE PREVALENCE OF VULVOVAGINAL CANDIDIASIS IN PREGNANT WOMEN ATTENDING SEVERAL HOSPITALS IN SANA’A, YEMEN
Authors: Humaid Abdulrahman , Alghalibi Saeed M , Al-Mahbashi Anes , AL-Arossi Aml , Edrees Wadhah Hassan 
Published: January 2020

Candida species are opportunistic yeasts affecting the genitourinary tract which causes the vulvovaginal candidiasis in the most female especially in developing countries. This study aims to determine the prevalence of vulvovaginal candidiasis caused by Candida species causing among pregnant women in Sana'a City, Yemen. This study was carried out at the department of microbiology of AL-Kuwait University Hospital. 250 vaginal swabs were collected and cultured on Sabouraud dextrose agar. Candida species identification and antifungal susceptibility testing were determined according to standard microbiological methods. The results showed that out of 250 samples, 63(25.2%) were positive for Candida species. It was found that the C. albicans (68.3%) was the most common species isolated followed by non-albicans species that are C. tropicalis (20.6%), C. glabrata (6.3%), and C. kefyr (4.8%). Also, it was recorded that the highest prevalence of Candida species was within group aged of 36-46 year. Susceptibility tests revealed that the most isolated species of C. andida were sensitive to nystatin (95%). miconazole was the next effective drug with 64% sensitive followed by amphotericin B (29%) and clotrimazole (24%). But only 6% of the isolates were sensitive to fluconazole. It can be concluded that the vulvovaginal candidiasis are quite common in Yemen country with a high prevalence. Also, the nystatin remains the effective agent against all isolated of Candida species. In contrast, the increase resistance of Candida species to fluconazole that commonly used antifungal is an alarming increase of vaginal candidiasis caused by antifungal-resistant Candida species.
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Received file

Average Peer review marks at initial stage: 5.0/10
Average Peer review marks at publication stage: 8.0/10
Reviewer(s) detail:
Name: Dr. Hassan A.H. Al-Shamahy
Affiliation: Sana'a University, Yemen
E-mail: shmahe@yemen.net.ye

Name: Dr. Tamer Mohamed Ali El Habibi
Affiliation: Suez Canal University, Egypt.
E-mail: tamer_hassan@pharm.suez.edu.eg

Name: Rola Jadallah
Affiliation: Arab American University, Palestine
E-mail: rola@aauj.edu
Comments of reviewer(s):

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