bluuebunny/crossref_metadata_2025_split huggingface dataset:
A distração da meninada nas ruas de São Paulo no início do século XX
Authors: Mimesse Prado Eliane 
Published: March 2020

As crianças e jovens que viviam na cidade paulistana nos anos iniciais do século XX tiveram seus momentos para a diversão, normalmente com grupos de amigos. Identificaram-se brincadeiras e jogos conhecidos entre esses sujeitos. A cidade de São Paulo crescia a cada dia, com a entrada de imigrantes das mais diversas etnias. As novas fábricas atraiam a mão de obra que estava ociosa no interior do estado. O aumento no fluxo de bondes para o transporte de passageiros e de carroças de serviços nas ruas cresceu, na mesma proporção que as fábricas. As ruas tornaram-se mais movimentadas e, consequentemente, mais perigosas, começaram a ameaçar e restringir a diversão da meninada. A fonte primária para este estudo foram as notícias de um periódico em circulação chamado O Estado de S. Paulo. As referências teóricas foram compostas por Cruz (2013) quando tratou da urbanização da cidade paulistana e de Pereira (2010) que focou no desenvolvimento fabril e urbano no início do século XX; Moura (2000) abordou a questão do trabalho infantil na urbe; e Autor (2018) por estudar os abandonados e órfãos na capital paulista; entre outros. Conclui-se que, apesar da expansão da cidade e do breve trânsito nas ruas, as crianças e jovens conseguiram divertir-se e encontrarem locais para sua recreação
UJI DAYA HAMBAT ANTIBAKTERI AIR PERASAN DAGING BUAH NANAS (ANANAS COMOSUS (L) MERR VAR. QUEEN) TERHADAP BAKTERI PROPIONIBACTERIUM ACNES
Authors: Sarwendah Sarwendah , Yusliana Yusliana , G Laia Heronimus Candra , Daely Pieter Julius , Chiuman Linda 
Published: March 2020

Abstrak: Buah nanas (Ananas comosus (L) Merr) merupakan salah satu jenis buah-buahan tropis yang banyak diminati masyarakat. Buah nanas biasa dingunakan masyarakat sebagai antibakteri, antiinflamasi, antikoagulan, dan antikanker. Tujuan dari penelitian ini untuk mengetahui uji daya hambat anti bakteri air perasan daging buah nanas (Ananas comosus (L) Merr Var.ÃÂ Queen) terhadap bakteri Propionibacterium acnes. Penelitian ini merupakan penelitian eksperimental laboratorium dengan menggunakan metode difusi kertas cakram. Hasil dari penelitian menunjukkan bahwa air perasan daging buah nanas (Ananas comosus (L) Merr Var. Queen) pada konsentrasi 25%, 50%, 75%, 100% memiliki efektivitas sedang sebagai antibakteri dalam menghambat pertumbuhan bakteri Propionibacterium acnes, pada kontrol positif yang menggunakan klindamisin dengan rata-rata diameter zona hambat sebesar 25,8 mm memiliki pengaruh antibakteri yang sangat kuat dan untuk kontrol negatif dengan menggunakan aquades tidak menunjukkan zona hambat 0 mm pada bakteri Propionibacterium acnes.Kata kunci: Buah nanas, propionibacterium acnes, daya hambat antibakteri.Abstract: Pineapple (Ananas comosus (L) Merr) is one of the most popular fruit among people, Pineapple is used as antibacterial, anti-inlfammatory, anticoagulant and anticancer. The purpose of this study is to determine the antibacterial inhibitory test of pineapple juice (Ananas comosus (L) Merr Var. Queen) against Propionibacterium acnes. This research is a laboratory experimental using paper disc diffisuion method. The results of this study indicate that pineapple juice at concentration of 25%, 50%, 75%, 100% it has a moderately antibacterial effectiveness in inhibit the growth of Propionibacterium acnes, positive control using clindamycin with an average inhibition zone diameter of 25.8 mm has a very strong antibacterial effect and for negative control using aquades does not show 0 mm inhibition zone in Propionibacterium acnes bacteria.Keywords: Pineapple fruit, propionibacterium acnes, antibacterial inhibition.
Perbedaan Keterampilan Proses Sains Biologi Siswa Sekolah Menengah Atas Berdasarkan Tingkat Akreditas Sekolah
Authors: Safahi Luthpi , Akbar Budhi , Selvianah Anah , Astuti Yuni , Anugrah Devi 
Published: March 2020

Penelitian ini bertujuan untuk mengetahui perbedaan keterampilan proses sains (KPS) Biologi siswa sekolah menengah atas akreditasi A dengan siswa sekolah menengah atas akreditasi B. Metode yang digunakan adalah deskriptif kausal kompratif. Populasi penelitian ini adalah siswa kelas XI SMA Swasta di Jakarta Barat Wilayah 1 Kecamatan Cengkareng tahun ajaran 2015/2016 yang berjumlah ±1.680 siswa. Pengambilan sampel dengan menggunakan teknik Cluster Random Sampling dan terpilih empat sekolah SMA Swasta dua Sekolah Akreditasi A (40 orang) dan dua Sekolah Akreditasi B (40 orang). Penelitian dilakukan pada bulan Januari – Juni 2016. Instrumen penelitian menggunakan tes objektif KPS yang terdiri dari 34 soal. Data penelitian dianalisis menggunakan Uji-t. Hasilnya menunjukkan thit (4,60) > ttabel (0,975) (1,99), Hipotesis ditolak, sehingga ada perbedaan keterampilan proses sains Biologi siswa sekolah menengah atas akreditasi A dengan siswa sekolah menengah atas akreditasi B.
Crowd Engineering – Produktentwicklung in der Community
Authors: Hertwig Michael , Barwasser Adrian , Lentes Joachim , Adam Frauke , Kalkuhl Johannes , Siee Maik 
Published: March 2020

Kurzfassung
Fachkräftemangel, immer kürzere Produktlebenszyklen und der zunehmende Bedarf an kundenindividuellen Produkten führen zu steigenden Herausforderungen für Entwicklungsabteilungen produzierender Unternehmen. Die Einbindung von externen Experten aus einer Community in firmeninterne Produktentwicklungsprozesse ist ein erfolgversprechender Ansatz für die schnellere, kostengünstigere und bedarfsangepasste Entwicklung von Produkten. Mit Crowd Engineering wird die Einbindung einer Community in eine Produktentwicklung realisiert. Dieser Beitrag soll einen Einblick in den aktuellen Forschungsstand des Crowd Engineerings geben und den Nutzen für Unternehmen aufzeigen.
Handlungsmuster der Feuerwehr für das Störungsmanagement?
Authors: Gronau Norbert 
Published: March 2020

Kurzfassung
Einsatzorganisationen, wie z. B. Feuerwehr oder Technisches Hilfswerk, müssen sehr schnell auf teilweise unbekannte Lagen reagieren und angemessene Hilfeleistung erbringen. Können Handlungsweisen und vorbereitende Maßnahmen dieser Organisationen auf die Störungsbeseitigung in Produktionssystemen übertragen werden? Ein Experiment in einem Cyber-Physischen Produktionssystem geht dieser Frage nach. Es zeigt sich, dass durch die Anwendung geeigneter Handlungsmuster sowohl die Dauer von Störungen als auch die Zeit für die Behebung verkürzt werden können.
Ứng xử ngang của gối cách chấn đàn hồi cốt sợi không liên kết hình khối hộp chịu chuyển vị lớn
Authors: Việt Vũ Quang , Thuyết Ngô Văn 
Published: March 2020

Gối cách chấn đàn hồi cốt sợi không liên kết (gọi tắt là gối U-FREI) là một loại gối cách chấn tương đối mới đang được phát triển trên thế giới. Các nghiên cứu về gối U-FREI ở Việt Nam mới chỉ xem xét gối U-FREI chịu chuyển vị ngang với giá trị nhỏ (nhỏ hơn 1,0tr, trong đó tr là tổng chiều dày các lớp cao su trong gối U-FREI). Trong nghiên cứu này, ứng xử ngang của gối U-FREI hình khối hộp chịu đồng thời tải trọng thẳng đứng có giá trị không đổi và chuyển vị ngang vòng lặp dạng hàm điều hòa có độ lớn tăng dần đến giá trị 2,0trđược khảo sát bằng phương pháp phân tích mô hình số. Nghiên cứu chỉ ra rằng tại các chuyển vị nhỏ, độ cứng ngang của gối U-FREI giảm xuống do gối cách chấn có biến dạng cuộn, nhưng ở các chuyển vị lớn, độ cứng ngang của gối U-FREI tăng lên.
Từ khóa:
gối cách chấn; gối cách chấn đàn hồi cốt sợi không liên kết; biến dạng cuộn; ứng xử ngang; chuyển vị ngang lớn.
EVALUASI PENGGUNAAN OBAT PADA PASIEN OSTEOARTRITIS DI INSTALASI RAWAT JALAN RSUD DR. M. ASHARI PEMALANG PERIODE MARET-APRIL 2018
Authors: S Fithri Zahara , A Ebta Narasukma , N.S.H Maria Caecilia 
Published: March 2020

ABSTRACT
Osteoarthritis (OA) is a degenerative joint illness characterized by cartilage destruction and
often found on older people. The drugs commonly used to treat OA symptoms is paracetamol,
nonsteroidal anti-inflammatory drugs (NSAIDs), food supplements such as glucosamine and
chondroitin. The purposes of these studies are identifying the OA patient's characteristics
(including gender and age), drug use evaluation based on the right patient, indication, and dose, as
well as the potency of drug interactions on OA patients. This research is non-experimental
research with a non-analytical descriptive design. The data was collected retrospectively with a
purposive sampling method from outpatients OA medical records in RSUD Dr. M. Ashari
Pemalang (March to April 2018 period). The results of this study indicate that patients have
suffered OA for 1-2 years (40%), generally women (72.94%) with an age range of 46-55 years
(39%). Most patients have an elementary school educational background (41%), and 43.53% of
them are overweight (BMI 25.00-29.99). All medicines prescribed for OA patient therapy have
been the right indication and patient. As many as 80.95% of the prescribed medicines had the right
dose, and 19.05% of prescription drugs case categorized as underdosing. Drug interactions
potency occurs in 30.58% of patients, with 29 cases.
Keywords: Osteoarthritis, drugs use evaluation, outpatient
Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage
Authors: Cicognola Claudia , Satir Tugce Munise , Brinkmalm Gunnar , Matečko-Burmann Irena , Agholme Lotta , Bergström Petra , Becker Bruno , Zetterberg Henrik , Blennow Kaj , Höglund Kina 
Published: March 2020

Background: Tau aggregation in neurons and glial cells characterizes tauopathies as Alzheimer’s disease (AD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Tau proteolysis has been proposed as a trigger for tau aggregation and tau fragments have been observed in brain and cerebrospinal fluid (CSF). Our group identified a major tau cleavage at amino acid (aa) 224 in CSF; N-terminal tau fragments ending at aa 224 (N-224) were significantly increased in AD and lacked correlation to total tau (t-tau) and phosphorylated tau (p-tau) in PSP and CBD. Objective: Previous studies have shown cleavage from calpain proteases at sites adjacent to aa 224. Our aim was to investigate if calpain-1 or -2 could be responsible for cleavage at aa 224. Methods: Proteolytic activity of calpain-1, calpain-2, and brain protein extract was assessed on a custom tau peptide (aa 220–228), engineered with fluorescence resonance energy transfer (FRET) technology. Findings were confirmed with in-gel trypsination and mass spectrometry (MS) analysis of brain-derived bands with proteolytic activity on the FRET substrate. Finally, knock-down of the calpain-2 catalytic subunit gene ( CAPN2) was performed in a neuroblastoma cell line (SH-SY5Y). Results: Calpain-2 and brain protein extract, but not calpain-1, showed proteolytic activity on the FRET substrate. MS analysis of active gel bands revealed presence of calpain-2 subunits, but not calpain-1. Calpain-2 depletion and chemical inhibition suppressed proteolysis of the FRET substrate. CAPN2 knock-down caused a 76.4% reduction of N-224 tau in the cell-conditioned media. Conclusions: Further investigation of the calpain-2 pathway in the pathogenesis of tauopathies is encouraged.
Analisis Pengaruh Variabel Ekonomi Makro terhadap Indeks Saham Syariah Indonesia (ISSI) periode 2016 - 2019
Authors: Chotib Emet , Huda Nurul 
Published: March 2020

Penelitian bertujuan untuk mengetahui pengaruh Nilai Tukar terhadap Pergerakan Indeks Saham Syariah Indonesia (ISSI); pengaruh Sertifikat Bank Indonesia Syariah (SBIS) terhadap Pergerakan Indeks Saham Syariah Indonesia (ISSI); pengaruh Sertifikat Bank Indonesia (SBI) terhadap Pergerakan Indeks Saham Syariah Indonesia (ISSI), dan pengaruh Penawaran Uang (M2) terhadap Pergerakan Indeks Saham Syariah Indonesia (ISSI). Metode analisa data yang digunakan adalah Analisa VAR dengan menggunakan software Eviews 5.0. Data diperoleh selama periode Januari 2016 sampai Januari 2019. Hasil penelitian menunjukkan bahwa Nilai Tukar berpengaruh terhadap pergerakan Indeks Saham Syariah Indonesia (ISSI) dan mendorong menurunnya Indeks Saham Syariah Indonesia (ISSI). Sertifikat Bank Indonesia Syariah (SBIS) berpengaruh terhadap pergerakan Indeks Saham Syariah Indonesia (ISSI) dan mendorong menurunnya Indeks Saham Syariah Indonesia (ISSI). Bank Indonesia Rate (BI) berpengaruh terhadap pergerakan Indeks Saham Syariah Indonesia (ISSI) dan mendorong meningkatnya Indeks Saham Syariah Indonesia (ISSI). Penawaran Uang (M2)/Jumlah Uang Beredar (JUB) berpengaruh terhadap pergerakan Indeks Saham Syariah Indonesia (ISSI) dan mendorong meningkatnya Indeks Saham Syariah Indonesia (ISSI).
‘The very sky and sea-line of her soul’: Nature, Destruction, and Desire in Dante Gabriel Rossetti's Poems
Authors: Trowbridge Serena 
Published: March 2020

When critics write of ‘truth to nature’ in Pre-Raphaelite poetry and painting, they rarely refer specifically to Rossetti. While his paintings situate women in medievalised environments saturated with floral imagery, nature itself seems relegated to an aesthetic function. This trope seems to be continued in his ballads in Poems, where the natural world is allied to the female figure and can be read as directly relating to the beauty of the woman. This essay will argue for a more complex and nuanced relationship between the poet and his poetic figures. Rossetti wrote of his concern that his poems should be free of ‘painter's tendencies’ (Fredeman IV: 413), and though the parallels between his paintings and his poems have been explored thoroughly, I shall argue that there is a disjunction when it comes to the depiction of the natural world, which serves a different, less aesthetic, and more intricate function in many of the poems. This approach is best traced in ‘The House of Life’ sonnets, where the relationship between the speaker's emotions, depicted through a series of environmental metaphors, and the concepts with which he struggles is one which can be unpicked by exploring his changing approach to nature.
The Role of the Glucocorticoid System in Anchorage-independence during Progression of Squamous Cell Carcinoma
Authors: Kennedy David , Pignatelli Massimo , Hassona Yazan , Prime Stephen S. , Cirillo Nicola 
Published: March 2020

Background: Topical and systemic corticosteroids are widely used for the treatment of mucocutaneous disorders including those with malignant potential. We have shown previously that normal keratinocytes regulate the local concentration of active steroids, as well as synthesize hydrocortisone de novo following stimulation with ACTH. The role of locally produced hydrocortisone in tumour progression is unclear.
Objective: To examine the ability of endogenously-produced and exogenously-administered hydrocortisone on the capacity of human keratinocytes to promote the formation of anchorage-independent multicellular aggregates (MCAs) in vitro.
Methods: The human keratinocyte cell line HaCaT derived from irradiated facial skin and c-Ha-ras-transfected HaCaT cell clones (I-7, II-3, RT-3) demonstrate increasing tumorigenic and metastatic potential in vivo and are ideally suited to studies of keratinocyte tumour progression. The formation of multicellular aggregates (MCAs) in vitro was used as a paradigm of metastatic potential in vivo.
Results: Non-tumorigenic (HaCaT), benign (I-7), malignant with low metastatic potential (II-3) and malignant with high metastatic capacity (RT-3) keratinocytes secreted basal levels of cortisol, activated cortisone and differentially synthesized cortisol de novo in the presence of ACTH; malignant cells (II-3 and RT-3) produced the highest levels of the steroid. When the cells were cultured in the absence of a substrate, RT-3 cell in particular were highly effective in forming MCAs and hydrocortisone further promoted MCA formation. Stimulation of the endogenous glucocorticoid system by ACTH caused an increase in MCA formation by II-3.
Conclusions: The data demonstrate that stimulation of the endogenous glucocorticoid system promotes anchorage independence of malignant keratinocytes in vitro.
A Panoramic Landscape of the Sagittarius Stream in Gaia DR2 Revealed with the STREAMFINDER Spyglass
Authors: Ibata Rodrigo , Bellazzini Michele , Thomas Guillaume , Malhan Khyati , Martin Nicolas , Famaey Benoit , Siebert Arnaud 
Published: March 2020

Abstract
We present the first full six-dimensional panoramic portrait of the Sagittarius stream, obtained by searching for wide stellar streams in the Gaia DR2 data set with the STREAMFINDER algorithm. We use the kinematic behavior of the sample to devise a selection of Gaia RR Lyrae, providing excellent distance measurements along the stream. The proper motion data are complemented with radial velocities from public surveys. We find that the global morphological and kinematic properties of the Sagittarius stream are still reasonably well reproduced by the simple Law & Majewski model (LM10), although the model overestimates the leading arm and trailing arm distances by up to ∼15%. The sample newly reveals the leading arm of the Sagittarius stream as it passes into very crowded regions of the Galactic disk toward the Galactic anticenter direction. Fortuitously, this part of the stream is almost exactly at the diametrically opposite location from the Galactic center to the progenitor, which should allow an assessment of the influence of dynamical friction and self-gravity in a way that is nearly independent of the underlying Galactic potential model.
Stabilization of Dayside Surface Liquid Water via Tropopause Cold Trapping on Arid Slowly Rotating Tidally Locked Planets
Authors: Ding Feng , Wordsworth Robin D. 
Published: March 2020

Abstract
Terrestrial-type exoplanets orbiting nearby red dwarf stars (M dwarfs) are among the best targets for atmospheric characterization and biosignature searches in the near future. Recent evolutionary studies have suggested that terrestrial planets in the habitable zone of M dwarfs are probably tidally locked and have limited surface water inventories as a result of their host stars’ high early luminosities. Several previous climate simulations of such planets have indicated that their remaining water would be transported to the planet’s permanent nightside and become trapped as surface ice, leaving the dayside devoid of water. Here we use a three-dimensional general circulation model with a water cycle and accurate radiative transfer scheme to investigate the surface water evolution on slowly rotating tidally locked terrestrial planets with limited surface water inventories. We show that there is a competition for water trapping between the nightside surface and the substellar tropopause in this type of climate system. Although under some conditions the surface water remains trapped on the nightside as an ice sheet, in other cases liquid water stabilizes in a circular area in the substellar region as a wetland. Planets with 1 bar N2 and atmospheric CO2 levels greater than 0.1 bar retain stable dayside liquid water, even with very small surface water inventories. Our results reveal the diversity of possible climate states on terrestrial-type exoplanets and highlight the importance of surface liquid water detection techniques for future characterization efforts.
L’extase déchiffrée
Authors: Kaltenbeck Franz 
Published: March 2020

Dans son essai sur Proust, Samuel Beckett explique, en 1930, la fonction que l’art a pour l’auteur d’ À la recherche du temps perdu . Proust suppose à l’art la clarté, écrit Beckett. Grâce à cette qualité, l’art peut déchiffrer « l’extase énigmatique » éprouvée par le narrateur de la Recherche quand il contemple « les formes impénétrables » de certains objets. Contrairement à l’esthétique de Schopenhauer, ce ne sont pas des objets extraordinaires qui déclenchent les extases de Proust. Beckett précise néanmoins que « le mystère, l’Idée, l’essence » y sont « prisonniers de la matière ». En relisant Proust et Beckett, nous montrons l’impact de ce débrouillage de l’extase par l’art pour la psychanalyse.
Religion de l’Égypte ancienne
Authors: Zivie-Coche Christiane 
Published: March 2020

Programme de l’année 2006-2007 : I. L’Ogdoade : élaboration et évolution d’une cosmogonie, du Nouvel Empire à l’époque ptolémaïque (suite) — II. Géographie religieuse : une approche du delta oriental
Institutions religieuses des cités grecques
Authors: Georgoudi Stella 
Published: March 2020

Programme de l’année 2004-2005 : La question controversée du sacrifice humain et les oracles grecs — Programme de l’année 2005-2006 : Dieux « olympiens », « ouraniens », « chthoniens » : nouvelles perspectives — Programme de l’année 2006-2007 : Organisation des sanctuaires et activité oraculaire en Béotie antique
Deux systèmes religieux dans l’Ancien Testament : de la concurrence à la convergence
Authors: Gonçalves Francolino J. 
Published: March 2020

Programme de l’année 2006-2007 : Introduction — I. Le yahvisme fondé sur le mythe de la création — II. Le yahvisme fondé sur l’histoire d’Israël avec son Dieu — III. La fusion des deux yahvismes
Techniques de la recherche en histoire moderne et contemporaine
Authors: Guillon Hélène 
Published: March 2020

Programme de l’année 2005-2006 : Ce séminaire a réuni des étudiants inscrits en Master II et en début de doctorat. Il avait pour but de fournir à ces étudiants de Sciences religieuses des outils méthodologiques leur permettant d’aborder la recherche historique […]
Histoire des chrétiens d’Orient (xvie-xxie siècle)
Authors: Heyberger Bernard 
Published: March 2020

Programme de l’année 2006-2007 : L’étude des parcours de « médiateurs », de ces chrétiens qui ont circulé entre l’Orient et l’Occident, ou qui, sans voyager, ont été entre les deux mondes de par leur situation : chrétiens gyrovagues et quêteurs d’aumônes dans l’Europe catholique […]
Histoire de l’exégèse chrétienne au Moyen Âge
Authors: Dahan Gilbert 
Published: March 2020

Programme de l’année 2006-2007 : I. Le Décalogue dans l’exégèse et la théologie, xiie‑xiiie siècles — II. L’exégèse du récit des pèlerins d’Emmaüs (Luc 24, 12‑35)
Le politique entre vie et mort
Authors: Revault d’Allonnes Myriam 
Published: March 2020

Programme de l’année 2006-2007 : « Le thème des conférences a poursuivi le travail des années précédentes, mené autour de la constitution affective du politique. En réfléchissant aujourd’hui sur sa propre spécificité mais aussi sur les conditions de l’actualité, la philosophie politique ne saurait manquer d’intégrer une analyse de la dynamique affective qui sous-tend la constitution des communautés politiques. […] »
Recherches sur les courants ésotériques dans l’Europe moderne et contemporaine
Authors: Faivre Antoine 
Published: March 2020

Programme de l’année 2006-2007 : I. Approches méthodologiques et constructions théoriques (depuis 1964 environ) portant sur l’objet de la spécialité — II. Les illustrations des œuvres de Böhme par Michael Andreae (1682) — III. Nouvelles enquêtes portant sur l’« éloquence magique »
« Entendre ce qui est sans voix » – le continent noir de la psychanalyse
Authors: Ginésy Pierre 
Published: March 2020

Programme de l’année 2006-2007 : « Cette conférence se propose d’interroger les impasses actuelles de la psychanalyse par l’interrogation de ses textes classiques, et, au‑delà, par le recours aux travaux d’épistémologie contemporaine, à l’ethnographie et à l’anthropologie historique. […] »