bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary Microcephaly with Novel Variant of MCPH1 Gene in Twins: Both Manifesting in Childhood at the Same Time with Hashimoto's Thyroiditis
Authors: Pavone Piero , Pappalardo Xena Giada , Praticò Andrea Domenico , Polizzi Agata , Ruggieri Martino , Piccione Maria , Corsello Giovanni , Falsaperla Raffaele 
Published: April 2020

AbstractThis study is a clinical report on twin females affected by primary microcephaly who displayed at molecular analysis of heterozygous novel MCPH1 variant. The twins at the age of 10 years developed, in coincidental time, a diagnosis of autoimmune juvenile thyroiditis. The main clinical features presented by the twins consisted of primary microcephaly with occipitofrontal circumference measuring −2 or −3 standard deviation, facial dysmorphism, typical nonsyndromic microcephaly, and mild intellectual disability. Molecular analysis of the major genes involved in primary microcephaly was performed and the following result was found in the twins: MCPH1; chr8.6357416; c.2180 C > T (rs 199861426), p.Pro727. Leu; heterozygous; missense; variant of uncertain significance (class 3). At the age of 10 years, the twins started to have, in coincidental time, marked asthenia and episodes of emotiveness, and laboratory exams disclosed a high level of antithyroid peroxidase leading to the diagnosis of autoimmune juvenile thyroiditis with normal thyroid function. The novel heterozygous MCPH1 variant found in the twins may be directly or indirectly involved in the onset of the primary microcephaly. The thyroid disorder in the twins and its onset, in a coincidental time, confirmed the effect of genetic predisposition on the pathogenesis of the immune thyroiditis.
Testing for dependence on tree structures
Authors: Behr Merle , Ansari M. Azim , Munk Axel , Holmes Chris 
Published: April 2020

Significance
Tree-like structures are abundant in the empirical sciences as they can summarize high-dimensional data and show latent structure among many samples in a single framework. Prominent examples include phylogenetic trees or hierarchical clustering derived from genetic data. Currently, users employ ad hoc methods to test for association between a given tree and a response variable, which reduces reproducibility and robustness. In this paper, we introduce treeSeg, a simple to use and widely applicable methodology with high power for testing between all levels of hierarchy for a given tree and the response while accounting for the overall false positive rate. Our method allows for precise uncertainty quantification and therefore, increases interpretability and reproducibility of such studies across many fields of science.
Reduced perceptual narrowing in synesthesia
Authors: Maurer Daphne , Ghloum Julian K. , Gibson Laura C. , Watson Marcus R. , Chen Lawrence M. , Akins Kathleen , Enns James T. , Hensch Takao K. , Werker Janet F. 
Published: April 2020

Significance
The perceptual validity of synesthesia has been established by behavioral and neuroimaging evidence; however, its developmental origins remain unclear. Here we tested the hypothesis that synesthesia arises when there is less experience-dependent pruning during development. We did so by comparing adults with and without synesthesia on another phenomenon that results from experience-dependent pruning: perceptual narrowing of discrimination to native categories (native phonemes and upright human faces) to the detriment of non-native categories (non-native phonemes, chimp faces, and inverted human faces). Synesthetes were better than controls at all of the non-native discriminations, with no difference for the native categories. The results support the hypothesis that in synesthesia, there is decreased experience-dependent modification of the cortical hyperconnectivity present in early development.
The role of variability in the control of the basketball dribble under different perceptual setups
Authors: Robalo Ricardo A. M. , Diniz Ana M. F. A. , Fernandes Orlando , Passos Pedro J. M. 
Published: April 2020

AbstractWhen executing a sport‐specific movement, athletes cannot use all perceptual resources to control their actions. The complexity of a basketball match, demands that individuals command their attention towards the context to make decisions. The dependency on the perceptual sources to control a movement should be kept to a minimum. During a match due to situational constraints, players often see themselves with impaired perceptual sources (e.g. auditory and peripheral vision occlusions). Assuming that professional basketball players are more skilled than amateurs, we analysed how both groups were affected by perceptual impairment, within and in‐between groups in a dribbling task. A variability analysis (correlation dimension, approximate entropy and Lyapunov exponent) was used to evaluate how an increased variability or stability, in a specific joint movement, contributes to a better adaptive behaviour when facing perceptual impairment. Professionals showed a significantly lower variability of the wrist movements, but had a significantly higher value of variability in the shoulder horizontal movements (anterior‐posterior and lateral), and also in the lateral elbow movements when their downwards peripheral vision was impaired. The increase in variability in such joint movements reflects adaptive behaviour and might be a performance factor.
1SWASP J034439.97+030425.5: a short-period eclipsing binary system with a close-in stellar companion
Authors: Zhang Bin , Qian Sheng-Bang , Wang Jing-Jing , Zhi Qi-Jun , Dong Ai-Jun , Xie Wei , Zhu Li-Ying , Jiang Lin-Qiao 
Published: April 2020

AbstractFirst multi-wavelength photometric light curves (LCs) of the short-period eclipsing binary (EB) 1SWASP J034439.97+030425.5 (hereafter J0344) are presented and analyzed by using the 2013 version of the Wilson-Devinney (W-D) code. To explain the asymmetric LCs of J0344, a cool star-spot on the less massive component was employed. The photometric solutions suggest that J0344 is a W-subtype shallow contact EB with a contact degree off= 4.9% ± 3.0% and a mass ratio ofq= 2.456 ± 0.013. Moreover, an obvious third light was detected in our analysis. We calculated the average luminosity contribution of the third light to the total light, and that value reaches up to 49.78%. Based on theO−Cmethod, the variations of the orbital period were studied for the first time. OurO−Cdiagram reveals a secular decrease superimposed on a cyclic oscillation. The orbital period decreases at a rate ofdP/dt= −6.07 × 10−7d yr−1, which can be explained by the mass transfer from the more massive component to the less massive one. Besides, itsO−Cdiagram also shows a cyclic oscillation with an amplitude of 0.0030 d and a period about 7.08 yr, which can be explained by the presence of a third body with a minimum mass ofM3min= 0.15 ± 0.02M⊙. The third component may play an important role in the formation and evolution of J0344 by drawing angular momentum from the central system.
MHD simulations of inward shocks in Cassiopeia A
Authors: Yang Chu-Yuan , Bao Bi-Wen , Liu Si-Ming 
Published: April 2020

Abstract
Cassiopeia A, the brightest radio supernova remnant (SNR) in the sky, has several unique characteristics in comparison to its peers. Besides its radio brightness and prominent soft-concave radio spectrum, its γ-ray spectrum appears to have a low-energy cutoff near 2 GeV, and it is the only SNR with prominent hard X-ray emission. While the unusual radio properties may be attributed to strong emission from reverse shocks, the hard X-ray emission has been associated with high-speed inward shocks induced by high density gases. Then, the low-energy γ-ray spectral cutoff could be attributed to slow penetration of lower energy particles accelerated near the inward shocks into high-density emission zone. In this paper, we carry out magneto-hydrodynamic (MHD) simulations of shocks in Cassiopeia A and demonstrate that its inward shock structure can indeed be reproduced via shock interactions with clumps of gases with a density of ∼ 20 cm−3.
Toward accurate measurement of property-dependent galaxy clustering: I. Comparison of the Vmax method and the “shuffled” method
Authors: Yang Lei , Jing Yi-Peng , Li Zhi-Gang , Yang Xiao-Hu 
Published: April 2020

Abstract
Galaxy clustering provides insightful clues to our understanding of galaxy formation and evolution, as well as the universe. The redshift assignment for the random sample is one of the key steps to accurately measure galaxy clustering. In this paper, by virtue of the mock galaxy catalogs, we investigate the effect of two redshift assignment methods on the measurement of galaxy two-point correlation functions (hereafter 2PCFs), the V
max method and the “shuffled” method. We have found that the shuffled method significantly underestimates both of the projected 2PCFs and the two-dimensional 2PCFs in redshift space, while the V
max method does not show any notable bias on the 2PCFs for volume-limited samples. For flux-limited samples, the bias produced by the V
max method is less than half of the shuffled method on large scales. Therefore, we strongly recommend the V
max method to assign redshifts to random samples in the future galaxy clustering analysis.
FRB 171019: an event of binary neutron star merger?
Authors: Jiang Jin-Chen , Wang Wei-Yang , Luo Rui , Du Shuang , Chen Xuelei , Lee Ke-Jia , Xu Ren-Xin 
Published: April 2020

Abstract
The fast radio burst, FRB 171019, was relatively bright when discovered first by ASKAP but was identified as a repeater with three faint bursts detected later by GBT and CHIME. These observations lead to the discussion of whether the first bright burst shares the same mechanism with the following repeating bursts. A model of binary neutron star merger is proposed for FRB 171019, in which the first bright burst occurred during the merger event, while the subsequent repeating bursts are starquake-induced, and generally fainter, as the energy release rate for the starquakes can hardly exceed that of the catastrophic merger event. This scenario is consistent with the observation that no later burst detected is as bright as the first one.
The activity of modern agricultural technique, mina paddy, on salt water and the income of farmers in west matang raya-north aceh regency
Authors: Aziz D 
Published: April 2020

Abstract
This is a study of activity in agricultural modern technique, mina paddy, on salt water and the income of Kena group farmer in West Matang Raya, North Aceh district. This study focuses on identifying the activity of modern agricultural technique on salt water and the income of farmers in Kena group. The major objective of this research is to find out the activity of modern agricultural technique on salt water and the income of Kena group. This study was conducted on February, 2017 with 20 members of Kena group. The data were obtained through library studies, documentations, observation, questionnaires and interviews. The data were analyzed descriptively. Based on the result of this study, the proper activity of modern agricultural technique, mina paddy, can increase the productivity of agricultural products and also increase the farmers’ income compared to the agricultural activities in general. It is suggested that the government can encourage the farmers to do the mina paddy technique on the proper land and help them by providing the fertilizer, seed, pesticide and feed. Therefore, the farmers will have no difficulties and get the motivation to do the mina paddy technique which can improve their prosperity and ensure their food security for the future, especially for the farmers in Kena group, West Matang Raya.
Observation of the Saibatin Traditional House with Biological – Architecture Approach
Authors: Fadilasari Dewi , Lisa Diana 
Published: April 2020

Abstract
Traditional house was one of the symbol of a previous culture that was inherited from generation to generation of each tribe, with a design adapted from the natural conditions of its time, which were built in such ways as to be used and utilized as needed at that time. The Saibatin traditional house is one of Lampung traditional house type, often called lamban or nuwo, also known as stilt houses, where full of symbol, philosophies, and cosmological content of Lampung culture. The objective of this research is to observe the Saibatin traditional houses located in Pekon Kenali, West Lampung Regency, with the biological–architecture approach. The research was conducted by observation methods and descriptive research to identify the object by comparing between data from literature and the results of documentation, as well as observations from research samples. The data from the object of research would be described and juxtaposed with the theories of biologic-architecture. The observations of The Saibatin Traditional House were executed on the whole part of the house inclusive of roof, wall, floor, columns, beam, stairs, foundation and basement. The results show that most parts of The Saibatin Traditional House are using natural materials which are part of biological architecture. The conclusion of observation research of The Saibatin Traditional House that biological architecture is not only suitable for the ancient building of old time, it also adaptable to nowadays situation, proven their existence can still adjust to the development of the era without leaving local wisdom.
Finite Element Stress Analysis of Acrylic with Embedded Optical Fibre Sensors
Authors: Kurdi O , Widyanto S A , Haryadi G D , Suprihanto A , Yulianti I , Rahman A 
Published: April 2020

Abstract
Finite element (FE) techniques are used to analyse mechanical stress in optical fibre sensors embedded in acrylic. The models represent many features observed in real materials with embedded fibre optic for stress and strain sensor application such as for health monitoring of structures. Three thicknesses, namely 6 mm, 8 mm and 10 mm of acrylic were analyzed with the optical fibre embedded at the mid-plane of acrylic. The simulation was done by implementing Finite Element Method using ABAQUS software. Contact between acrylic and optical fibre was modelled as frictionless and with friction. The friction coefficient was varied for various values which are 0.3, and 0.5. This paper investigates the effect of friction coefficient and the effect of fibre optic’s depth embedded in acrylic to the their von Misses stress. Simulation result shows that the higher the friction coefficient the higher von Misses stress in fibre optic and the higher von Misses stress in acrylic. The higher the fibre’s depth the higher von Misses stress in fibre and the lower von Misses stress in acrylic. The maximum stress occurred for the coefficient of friction 0.5, with magnitude of 116.4 MPa and 58.72 MPa for acrylic and optical fibre respectively. The most significant effect of fibre’s depth to the von Misses stress was obtained for 1 mm depth for acrylic and 5 mm for optical fibre, with magnitude of 72.64 MPa and 57.65 MPa for acrylic and optical fibre respectively.
Study the Effect of Dummy Slot in Stator and Rotor on the Cogging Torque Reduction in Permanent Magnet Machine
Authors: Joe Liza Evelyn , Nur Tajuddin 
Published: April 2020

Abstract
In this study, the effect of dummy slot in stator core and magnet in rotor core greatly affects the value of the cogging torque reduction in permanent magnet machine. The structure of permanent magnet machine was analysed employed finite element based on the finite element method magnetic (2D). In this study, 4 type of permanent magnet machine structure has been analysed. Permanent magnet machine structure in rotor have 4 type design magnet, permanent magnet machine with initial structure magnet, bread loaf, magnet edge slotting, and magnet edge slotting-magnet slot of surface. The cogging torque reduction of the proposed permanent magnet machine were computed and compared with the initial structure. Using the finite element, authors have computed and found that the cogging torque reduction of type 3 and type 1. The cogging torque of proposed permanent magnet machine could be reduced to 97.17% by employing the dummy slot in stator core.
Study of The Effect of Height and Length of Slotting in Magnet Edge on the Cogging Torque Reduction of Fractional Slot Number in Permanent Magnet Machine
Authors: Nur Tajuddin , Joe Liza Evelyn 
Published: April 2020

AbstractCogging torque generated in permanent magnet machine effects to some undesirable vibration and noises. In order to minimize the cogging torque in permanent magnet is the most important issues recently. This paper investigated the influence of the value of height and length of slotting in magnet edge on the cogging torque reduction. For purpose of study the structure of 24 slot/10 pole of permanent magnet machines have been chosen. The 2-D finite element based on FEMM 4.2 software was implemented to compute the permanent magnet machine performance. Simulation results showed that by optimising the height and length of slotting in magnet edge can reduce the cogging torque of permanent magnet machine significantly. The most effective way by employing a-two step slotting with 2.5 mm of height and 0.7 mm of length of the slotting in magnet in the first step of slotting. In the second step of in magnet edge, the length of slotting has been assigned as much as 2.3 mm and the height of slotting was 0.588635 mm. By employing the FEMM, three of different magnet structures of permanent magnet machine were analysed. It was found that the cogging torque of permanent magnet machine proposed magnet structure as much as 99.7 % compared with the initial structure of the permanent magnet machine.
Road Improvement Overlay Pavement Flexible at Cibomo – Terumbu Road Serang City
Authors: Rosdiyani Telly , Artiwi Nila Prasetyo , Suratman Ogi 
Published: April 2020

Abstract
Cibomo - Terumbu road to makes an alternative as connecting road (Axis) residential area in Kasemen District, Serang City. There are some damage conditions on the road structure and there is absence of adequate drainage channel with heavy traffic through the road, which lead congestion and inconvenience in driving. It is necessary to solve these problems. This research was conducted to determine the thickness of the pavement layer, and to design the dimensions of the drainage channel. The method used in this planning was the calculation of Bina Marga 1987. Geometric control of the road based on the Road Geometric Planning Basics 1999, while drainage planning was used in the Procedure for Road Surface Drainage Planning (SNI-03-34241994). Planning period for 15 (fifteen) years. The final results of the plan require an additional layer of 6 (six) cm Laston (Concrete Asphalt Surface Coating) MS 590. The size of the drainage channel in accordance with the calculation, channel height (h) is 0.40 m, the channel width (b) is 0.30, and the watch height (w) is 0.45.
Thermal treatment for radioactive waste minimisation and hazard reduction: overview and summary of the EC THERAMIN project
Authors: Scourfield S J , Kent J E , Wickham S M , Nieminen M , Clarke S , Frasca B 
Published: April 2020

Abstract
The EC THERAMIN project aimed to identify which wastes could benefit from thermal treatment, which treatment technologies are under development in participating countries, and how these could be combined to deliver a wide range of benefits. Thermal pre-treatment or immobilisation processes result in significant volume reduction, waste passivation and destruction of organic materials, which reduces risks during waste storage and supports development of safety cases for geological disposal. This paper presents the key conclusions from the project. The potential for thermal treatment of European radioactive waste streams was evaluated and a “Value Assessment” framework was developed to assist in decision making, taking into account all stages of the waste management lifecycle. An overview is given of the strategy followed in performing demonstration trials and subsequent waste product characterisation for a range of waste groups. Case studies for select demonstrator-waste group combinations provide information about these processes in greater depth, including details about the treatment technique, resulting waste product and its characterisation, and disposability implications. Finally, the key conclusions from the project are summarised.
In-Can vitrification of ash
Authors: Fournier M , Massoni N , Hollebecque J F 
Published: April 2020

Abstract
The In-Can Melter is a metallic crucible heated in a refractory furnace using electrical resistors allowing in-container vitrification. The In-Can Melter trial aims to demonstrate the feasibility of the confinement in a glassy matrix of ash coming from existing incineration processes. The ash was pelletised to allow its introduction into the can without dust emissions and then incorporated in a 50 wt.% waste loading confinement matrix. The full-scale trial was preceded by laboratory- and bench-scale tests. The microstructure and chemical durability of the wasteform were characterised.
Hot Isostatically Pressed Zirconolite Wasteforms for Actinide Immobilisation
Authors: Blackburn L R , Gardner L J , Sun S K , Maddrell E R , Stennett M C , Corkhill C L , Hyatt N C 
Published: April 2020

Abstract
In order to demonstrate the deployment of Hot Isostatic Pressing (HIP) for the immobilisation of Pu stocks and residues, a series of active and inactive zirconolite formulations have been processed and characterised. In this instance, Ce, U, and Th have been applied as chemical surrogates for Pu4+. A range of formulations targeting isovalent Zr4+ site substitution (i.e. to simulate CaZr1-xPuxTi2O7) have been processed by HIP and characterised by powder X-ray diffraction, and scanning electron microscopy, in order to determine surrogate partitioning between the host zirconolite phase, and accessory phases that may have formed during the HIP process.
Development of Generic Criteria for Evaluating the Disposability of Thermally Treated Wastes
Authors: Harvey L , Galson D , Catherin S , Romero M-A , Fournier M , Fuller A , Wickham S 
Published: April 2020

Abstract
The potential to generate wasteforms with enhanced properties that support safe storage and disposal is one of the key factors driving thermal treatment of radioactive waste. Depending on the specific treatment method and waste substrate, thermal treatment can greatly reduce chemical reactivity, yielding a primary product that is more durable than wasteforms produced via non-thermal routes and with reduced potential for gas generation and other detrimental behaviour in a storage / disposal environment. On the other hand, thermal treatment can concentrate radioactivity into a smaller volume, potentially affecting waste handling and / or classification. It also generates secondary wastes whose management requires consideration as part of a holistic evaluation of thermal treatment. Moreover, some thermal treatment routes do not generate a primary product that is directly disposable without further conditioning. Generic disposability criteria have been derived that can be used to evaluate the primary products from any form of thermal treatment. These generic disposability criteria highlight the factors that are relevant for waste product disposability and the ways in which thermal treatment can impact on these factors (both positively and negatively). They are equally applicable to any packaging or disposal concept, regardless of the engineered barriers that are present, and in any disposal environment, regardless of its characteristics and the nature of the host rock / geology. They could aid waste management organisations in developing their own disposability criteria, tailored to a particular context, for application in national waste management programmes.