bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the induction heating contribution in magnetic pulse forming processes for tube forming application
Authors: Bay Francois , Alves Jose 
Published: January 2020

Purpose
The purpose of this paper is to study the influence of the induction heating phenomenon during magnetic pulse forming (MPF) of thin walled tube components. The approach is based on the advanced use of the multiphysics finite element software FORGE® coupling electromagnetism, heat transfer and solid mechanics. Although the global contribution of thermal effects is found to be almost negligible with respect to the volume forces, it can be observed that localized softening due to the heating process induces shock absorbing behavior.

Design/methodology/approach
Due to the strong multiphysics couplings between solid mechanics, electromagnetism and heat transfer, it is not always obvious to quantify the contributions of the various physical phenomena. It is thus intended here to take advantage of the numerical framework and tool that has developed to dissociate and quantify the influence of Joule heating phenomena due to eddy currents during MPF processes.

Findings
In this paper, the sensitivity of the MPF process has been analyzed to the induction heating source term for a specific tube forming case. An analysis of the electric output signal shows that inductance sensitivity to heating remains small when compared to the mechanical deformation. Regarding mechanical analysis of the process, induction heating contribution has a very slight impact at the global scale, but its effect is more noticeable at the small scale where it is likely that the localized heating induces shock absorption properties through softening. The extension of these results to other materials (for which the thermal dependency of mechanical behavior is different), as well as to a larger range of energy inputs, still needs to be carried out. Such phenomena should be considered for instance for high precision forming.

Originality/value
The analysis of the influence of heating due to eddy currents in magnetic pulse forming processes has not been extensively studied. The originality of this work is to try to quantify its effect on the process by using a numerical-based approach.
Impact of employee job satisfaction and commitment on customer perceived value
Authors: Charni Hanen , Brun Isabelle , Ricard Line 
Published: January 2020

PurposeThe purpose of this paper is to analyse the impact of employee job satisfaction and affective commitment as perceived by customers on customer perceived value, more specifically its benefits dimensions.Design/methodology/approachA total of 652 panellists from a large Canadian polling firm self-administer a web-based questionnaire. To measure customer perceived value, a formative index is used which contributes to topical literature through a unique methodology. Hypotheses are tested using a structural equation model.FindingsAn analysis of the direct, indirect and total effects confirms the unique positive impact of employee job satisfaction and affective commitment, as perceived by customers, on the emotional, social, relationship and epistemic benefits, as well as on the formative index of customer perceived value.Practical implicationsCustomer perceptions of employee attitudes (job satisfaction and affective commitment) represent a unique opportunity for banks to differentiate their value proposition in a hypercompetitive market.Originality/valueThis study is the first to consider customer perceptions of employee job satisfaction and affective commitment in relation to a formative index of customer perceived value and its related benefits dimensions.
Risk governance and bank profitability in ASEAN-5: a comparative and empirical study
Authors: Karyani Etikah , Dewo Setio Anggoro , Santoso Wimboh , Frensidy Budi 
Published: January 2020

PurposeThe purpose of this paper is to highlight the disparity between the disclosures of risk governance (RGOV) categories, namely, structures both at the board and management level, and RGOV practices among five of the Association of Southeast Asian Nations (ASEAN-5) countries. Furthermore, this paper investigates the effects of RGOV and its categories on return on assets (ROA).Design/methodology/approachUsing 285 ASEAN-5 bank-year observations comprising hand-collected data for the period of 2010–2014, RGOV indexes are developed on the basis of 12 of the 13 governance guidelines published by the Basel Committee.FindingsAlthough some banks are found to be early adopters, there is an increasing trend of disclosure for all of the investigated categories. Furthermore, there are no effects of the overall RGOV, board-level RGOV structure and risk management practice on ROA. However, the effect of the management-level RGOV structure on ROA is negative and significant.Research limitations/implicationsMeasurements of RGOV indexes are based solely on the examination of criteria that have not been previously tested. Other limitations are related to the information completeness, subjectivity and interpretation.Practical implicationsManagement-level RGOV tends to decrease profitability because of the additional costs related to its implementation. Financial regulators may find this result useful as feedback to evaluate the effectiveness of regulation and possible future improvements.Originality/valueThis paper’s uniqueness lies in constructing new RGOV indexes on the basis of the latest bank governance guidelines from the Basel Committee issued on July 9, 2015.
Synergistic impacts of co‐occurring invasive grasses cause persistent effects in the soil‐plant system after selective removal
Authors: Zenni Rafael D. , da Cunha Wanderson L. , Musso Carolina , de Souza Jocemara V. , Nardoto Gabriela B. , Miranda Heloisa S. 
Published: January 2020

AbstractHuman influence on the environment is so extensive that virtually all ecosystems on the planet are now affected by biological invasions. And, often, ecosystems are invaded by multiple co‐occurring non‐native species. Hence, it is important to understand the impacts these invasions are producing on biodiversity and ecosystem processes.Here, we present results of a 2‐year long field experiment where we tested the effects of co‐occurring invasive C4African grasses in a Cerrado area in central Brazil. We compared plant and arthropod communities, plant biomass, and soil nitrogen dynamics and soil chemical characteristics across five experimental treatments:Urochloa decumbensremoval;Melinis minutifloraremoval; bothU.decumbensandM.minutifloraremoval;U.decumbensandM.minutiflorainvaded plots; and uninvaded Cerrado. We hypothesized that selective removal of invasive grasses would have distinct effects on the native ecosystem structure and functioning. We expected that each invasive grass would produce a different type of impact on the native ecosystem and that their impacts would be synergistic when co‐occurring.Removal ofM.minutifloradoubled native plant diversity and biomass when compared to invaded plots, whereas removal ofU.decumbensdid not alter these parameters. Cerrado plots had four times more plant species than plots cleared of invasives. Removal of invasive grasses did not affect the species richness or community composition of soil epigeal fauna. Cerrado soils had lower fertility, organic matter content and pH than invaded soils. The effects were generally higher when both invasive grasses were removed, suggesting impacts were synergistic, butM.minutiflorahad greater effects on plants and soils thanU.decumbens. Both invasive species produced negative impacts, but a single species was the main driver. We also detected persistent effects of the invasive grass species on the ecosystem after 2 years of removal.We conclude that invasive species of the same functional group have similar types of effects in native ecosystems, but the magnitude of impact was largely dependent on invasive species biomass and cover. Where multiple invasive species are present, research and management of invaded ecosystems should tackle the interacting effects of co‐occurring invaders.
Antibacterial applications of metal–organic frameworks and their composites
Authors: Shen Mofei , Forghani Fereidoun , Kong Xueqian , Liu Donghong , Ye Xingqian , Chen Shiguo , Ding Tian 
Published: January 2020

AbstractMetal–organic frameworks (MOFs) are porous coordination materials composed of multidentate organic ligands and metal ions or metal clusters. MOFs have the great potential to be utilized in antibacterial materials for biological, environmental, and food antimicrobial fields. In recent years, MOFs have been applied to various antibacterial fields due to their sustained release capability, porosity, and structural flexibility in combination with many chemicals and/or materials (such as nanoparticles, antibiotics, phytochemicals, and polymers). This review offers a detailed summary of the antibacterial applications of MOFs and their composites, focusing on the combination types of MOFs composites and the antibacterial effect in different applications. These applications are illustrated by the examples discussed in this review.
The Effects of Creative Culture on Real Earnings Management*
Authors: Guggenmos Ryan D. , Van der Stede Wim A. 
Published: January 2020

ABSTRACTCreativity and innovation have been identified by senior executives as some of the most desired characteristics of corporate culture. Accordingly, managers strive to build these cultures within their organizations. However, research in psychology suggests that these attempts may have unintended negative consequences. In this study, I predict and find that managers in a more (versus less) innovative company culture will engage in higher levels of real earnings management (REM). I then test two construal level theory (CLT)‐based interventions designed to reduce REM. As I predict, I find that in more innovative corporate cultures an intervention that makes downside risk more salient reduces REM, but an intervention that encourages managers to consider the “big‐picture” impact of their decision reduces REM to a greater extent. Unexpectedly, I also find that the effect of the “big‐picture” intervention reverses in a less innovative corporate culture leading to an increase in REM. My findings contribute to the emerging accounting literature regarding REM. I also extend the psychology literature investigating the link between opportunistic behavior and creativity, and I also expand research into how interventions based on CLT can affect judgment and decision making in an accounting context.
Novel M2‐selective, Gi‐biased agonists of muscarinic acetylcholine receptors
Authors: Randáková Alena , Nelic Dominik , Ungerová Dana , Nwokoye Peter , Su Qiwen , Doležal Vladimír , El‐Fakahany Esam E. , Boulos John , Jakubík Jan 
Published: January 2020

Background and PurposeMore than 30% of currently marketed medications act via GPCRs. Thus, GPCRs represent one of the most important pharmacotherapeutic targets. In contrast to traditional agonists activating multiple signalling pathways, agonists activating a single signalling pathway represent a new generation of drugs with increased specificity and fewer adverse effects.Experimental ApproachWe have synthesized novel agonists of muscarinic ACh receptors and tested their binding and function (on levels of cAMP and inositol phosphates) in CHO cells expressing individual subtypes of muscarinic receptors, primary cultures of rat aortic smooth muscle cells and suspensions of digested native tissues from rats. Binding of the novel compounds to M2 receptors was modelled in silico.Key ResultsTwo of the tested new compounds (1‐(thiophen‐2‐ylmethyl)‐3,6‐dihydro‐2H‐pyridinium and 1‐methyl‐1‐(thiophen‐2‐ylmethyl)‐3,6‐dihydro‐2H‐pyridinium) only inhibited cAMP synthesis in CHO cells, primary cultures, and native tissues, with selectivity for M2 muscarinic receptors and displaying bias towards the Gi signalling pathway at all subtypes of muscarinic receptors. Molecular modelling revealed interactions with the orthosteric binding site in a way specific for a given agonist followed by agonist‐specific changes in the conformation of the receptor.Conclusions and ImplicationsThe identified compounds may serve as lead structures in the search for novel non‐steroidal and non‐opioid analgesics acting via M2 and M4 muscarinic receptors with reduced side effects associated with activation of the phospholipase C signalling pathway.
Diffuse capillary malformation with overgrowth contains somatic PIK3CA variants
Authors: Goss Jeremy A. , Konczyk Dennis J. , Smits Patrick , Sudduth Christopher L. , Bischoff Joyce , Liang Marilyn G. , Greene Arin K. 
Published: January 2020

AbstractDiffuse capillary malformation with overgrowth (DCMO) is a clinical diagnosis describing patients with multiple, extensive capillary malformations (CMs) associated with overgrowth and foot anomalies. The purpose of the study was to identify somatic variants in DCMO. Skin containing CM and overgrown subcutaneous adipose tissue was collected from patients with DCMO. Exons from 447 cancer‐related genes were sequenced using OncoPanel. Variant‐specific droplet digital PCR (ddPCR) independently confirmed the variants and determined variant allele frequencies (VAF). One subject contained a somatic PIK3CA p.G106V variant. A second patient had a PIK3CA p.D350G variant. VAF was 27% to 29% in skin and 16% to 28% in subcutaneous adipose. Variants were enriched in endothelial cells (VAF 50%‐51%) compared to nonendothelial cells (1%‐8%). DCMO is associated with somatic PIK3CA variants and should be considered on the PIK3CA‐related overgrowth spectrum (PROS). Variants are present in both skin and subcutaneous adipose and are enriched in endothelial cells.
Impact of fast‐food outlet density on incidence of myocardial infarction in the Hunter region
Authors: Saluja Tarunpreet , Davies Allan , Oldmeadow Chris , Boyle Andrew J. 
Published: January 2020

AbstractBackgroundThere is an established association between fast‐food consumption and metabolic diseases. Some studies also suggest that calorie‐dense food promotes a proinflammatory response, which is itself linked with myocardial infarction (MI). Whether increased fast‐food availability is a risk factor for MI remains unknown.AimTo investigate the role of fast‐food outlet density (FFD) as a novel environmental risk factor for MI in the Hunter region, New South Wales (NSW).MethodsWe conducted a retrospective cohort study using a database of all MI events between 1996 and 2013, extracted from the Hunter Cardiac and Stroke Outcomes unit. FFD was calculated for each local government area (LGA) of the Hunter region, allowing for a comparative analysis. Stratification by fast‐food outlet data and LGA resulted in a total of 3070 cases. Weighted linear regression was used to investigate the role of FFD on incidence of MI in regional and rural Australia.ResultsFFD was positively correlated with rates of MI, remaining consistent in both single and multivariate predictor models adjusting for age, obesity, hyperlipidaemia, hypertension, smoking status, diabetes and socioeconomic status (P < 0.001). An increase of one fast‐food outlet corresponded with four additional cases of MI per 100 000 people per year (4.07, 95% confidence interval, 3.86–4.28).ConclusionsFFD was positively associated with incidence of MI in both rural and metropolitan areas of NSW. This relationship remained consistent after multivariate adjustment for standard cardiovascular risk factors, highlighting the importance of an individual's food environment as a potential contributor towards their health.
Thermal properties and elastic constants of ζ‐Ta4C3−x
Authors: Schwind Evan C. , Hilmas Gregory E. , Fahrenholtz William G. 
Published: January 2020

AbstractThermal and elastic properties were measured for ceramics that contained as much as 96 wt% zeta phase tantalum carbide (ζ‐Ta4C3−x). The ceramics were produced from tantalum hydride that was milled to reduce particle size and then blended with carbon. Powders were reaction hot‐pressed at 1800°C for 2 hours under a flowing He environment, which resulted in ζ‐Ta4C3−x that was about 99% dense. The main secondary phases present in the reacted ceramic were TaC and Ta2O5. ζ‐Ta4C3−x had a thermal conductivity of 9.6 W/m·K and an electrical resistivity of 160 ± 4.2 μΩ‐cm, which are lower and higher than those of TaC, respectively. The Young's modulus was 379 ± 5 GPa and the hardness was 5.1 ± 0.7 GPa, which are also both lower than TaC. This study is the first to report the thermal properties and elastic moduli of high‐purity ζ‐Ta4C3−x.
An atrial fibrillation rotor, mapped conventionally
Authors: Varma Niraj , Rizzo Raymond , Wisnoskey Brian 
Published: January 2020

AbstractThis case illustrates that the condition of atrial fibrillation (AF) may harbor site(s) of regular rotational activity, reentry may be an underlying mechanism, high periodicity and wavebreak through areas of the scar may generate fibrillatory conduction, and disintegration of the “rotor” may not abolish AF.
Impact of paced left ventricular dyssynchrony on left ventricular reverse remodeling after cardiac resynchronization therapy
Authors: Gauthey Anaïs , Willemen Erik , Lumens Joost , Ploux Sylvain , Bordachar Pierre , Ritter Philippe , Prinzen Frits W. , Lejeune Sibille , Pouleur Anne‐Catherine , Garnir Quentin , Marchandise Sébastien , Scavée Christophe , Wauters Aurélien , le Polain de Waroux Jean‐Benoit 
Published: January 2020

AbstractIntroductionWe investigated whether pacing‐induced electrical dyssynchrony at the time of cardiac resynchronization therapy (CRT) device implantation was associated with chronic CRT response.Methods and ResultsWe included a total of 69 consecutive heart failure patients who received a CRT device. Left (LVp‐RVs) and right (RVp‐LVs) pacing‐induced interlead delays were measured intraoperatively and used to determine if there was paced left ventricular (LV) dyssynchrony, defined as present when LVp‐RVs is larger than RVp‐LVs. CRT response was defined as a reduction in LV end‐systolic volume ≥15%, 6 months after implantation. Paced left ventricular dyssynchrony (PLVD) was associated with ischemic cardiomyopathy (ICM) (χ2: 8; P = .005) but not with QRS morphology nor with pacing lead positions. In a univariate analysis, PLVD (odds ratio [OR], 6.53; 95% confidence interval [CI], 2.2‐18.9; P = .001), atypical left bundle branch block (LBBB) (OR, 3.3; 95% CI, 1.2‐9.4; P = .022), and ICM (OR, 5.2; 95% CI, 1.6‐17; P = .006) were associated with nonresponse. In a multivariate analysis, both PLVD (OR, 9.74; 95% CI, 2.8‐33.9; P < .0001) and atypical LBBB (OR, 5.6; 95% CI, 1.5‐20.3; P = .009) were independently associated with nonresponse. Adding PLVD to a model based on QRS morphology provided a significant and meaningful incremental value to predict LV reverse remodeling after CRT (χ2 to enter: 8; P < .005). Computer simulations corroborate these findings by showing that, while intrinsic electrical dyssynchrony is a prerequisite, the level of pacing‐induced dyssynchrony modulates acute CRT response.ConclusionIn addition to the intrinsic electrical substrate, PLVD is strongly associated with less LV reverse remodeling, demonstrating that measuring the electrical substrate during pacing has additional value for prediction of CRT response in an already well‐selected patient population.
Exogenous 8‐hydroxydeoxyguanosine ameliorates liver fibrosis through the inhibition of Rac1‐NADPH oxidase signaling
Authors: Shin Seung Kak , Kim Kyung‐Ok , Kim Se‐Hee , Kwon Oh Sang , Choi Cheol Soo , Jeong Sung Hwan , Kim Yun Soo , Kim Ju Hyun , Chung Myung‐Hee 
Published: January 2020

AbstractBackground and AimExogenous 8‐hydroxydeoxyguanosine (8‐OHdG) was suggested as an inhibitor of Rac1 and NADPH oxidase (NOX). The aim of this study was to evaluate the effects of the exogenous 8‐OHdG on hepatic fibrogenesis in vitro and in vivo model of liver fibrosis.MethodsAdult Sprague–Dawley rats were allocated to sham‐operated rats (n = 7), rats that underwent bile duct ligation (BDL) (n = 6), and BDL rats treated with 8‐OHdG (60 mg/kg/day by gavage, n = 6). All rats were sacrificed on day 21. Double immunofluorescence staining between either NOX1 or NOX2 and α‐smooth muscle actin (SMA) in liver was performed. Hepatic fibrotic contents were assessed by hydroxyproline assay and quantified by Sirius red staining. In vitro, hepatic stellate cell (HSC) line LX‐2 and HHSteC cells were stimulated by angiotensin II (10 μM). The reactive oxygen species (ROS) production was measured by confocal microscopy. The expressions of NOX1, NOX2, α‐SMA, transforming growth factor (TGF)‐β1, and collagen Iα were analyzed by quantitative real‐time polymerase chain reaction or immunoblotting.ResultsThe 8‐OHdG treatment in BDL rats reduced the NOX1 and NOX2 protein expression, which overlapped with α‐SMA compared with BDL rats. The 8‐OHdG treatment in BDL rats significantly decreased the mRNA expression of NOX1, NOX2, α‐SMA, TGF‐β1, and collagen Iα, and fibrotic contents. Increases of ROS production, Rac1 activation, NOX1, NOX2, and fibronectin expression induced by angiotensin II in HSCs were attenuated by 8‐OHdG.ConclusionsRac1 activation and NOX‐derived ROS are implicated to liver fibrosis. The 8‐OHdG ameliorates liver fibrosis through the inhibition of Rac1 activation and NOX‐derived ROS.
Adaptations in pediatric anesthesia care and airway management in the resource‐poor setting
Authors: Manyumwa Petros , Chimhundu‐Sithole Tsitsi , Marange‐Chikuni Danai , Evans Faye M. 
Published: January 2020

AbstractThe need for safe and quality pediatric anesthesia care in low‐ and middle‐income countries (LMICs) is huge. An estimated 1.7 billion children do not have access to surgical care, and the majority are in LMICs. In addition, most LMICs do not have the requisite surgical workforce including anesthesia providers. Surgery is usually performed at three levels of facilities: district, provincial, and national referral hospitals. Unfortunately, the manpower, equipment, and other resources available to provide surgical care for children vary greatly at the different level facilities. The majority of district level hospitals are staffed solely by non‐physician anesthesia providers with variable training and little support to manage complicated pediatric patients. Airway and respiratory complications are known to account for a large portion of pediatric perioperative complications. Management of the difficult pediatric airway pathology is a challenge for anesthesia providers regardless of setting. However, in the low‐resource setting poor infrastructure, lack of transportation systems, and crippled referral systems lead to late presentation. There is often a lack of pediatric‐sized anesthesia equipment and resources, making management of the local pathology even more challenging. Efforts are being made to offer these providers additional training in pediatric anesthesia skills that incorporate low‐fidelity simulation. Out of necessity, anesthesia providers in this setting learn to be resourceful in order to manage complex pathologies with fewer, less ideal resources while still providing a safe anesthetic.