bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of 311 contemporary cases of stereotactic biopsies in patients with neoplastic and non-neoplastic lesions—diagnostic yield and management of non-diagnostic cases
Authors: Pasternak Krystyna Agnieszka , Schwake Michael , Warneke Nils , Masthoff Max , Zawy Alsofy Samer , Suero Molina Eric , Stummer Walter , Schipmann Stephanie 
Published: September 2020

AbstractStereotactic biopsies are an established tool for obtaining diagnosis of unclear brain lesions. However, non-diagnostic biopsies still occur. We aimed to analyze the contemporary diagnostic yield of stereotactic biopsies, predictors for non-diagnostic biopsies, outcome, and follow-up strategy after non-diagnostic biopsy. We conducted a single-center retrospective study of 311 adult patients undergoing stereotactic biopsies due to a newly diagnosed lesion at our department between 2012 and 2018. Patient data regarding comorbidities, presenting symptoms, imaging features, and non-invasive diagnostic procedures were obtained. The overall diagnostic yield was 86.2% and differed significantly between the various suspected diagnosis groups and was the highest when suspecting primary brain tumor compared with non-neoplastic lesions (91.2% vs. 73.3%, p > 0.001). Predicators for non-diagnostic biopsies were small lesion size, lack of contrast-enhancement, presence of sepsis, or underlying hemato-oncological disease. In case of non-diagnostic biopsy, a re-biopsy was performed in 12 cases, revealing a final diagnosis in 75%. In 16 cases, empiric therapy was started based on the suspected underlying disease. Close follow-up was performed in the remaining 15 cases. We showed that stereotactic biopsy is a safe procedure with reasonable diagnostic yield even for non-neoplastic lesions, when non-invasive diagnostic was inconclusive. In addition, we developed treatment recommendations for cases of non-diagnostic biopsies.
Integration of a Building Energy Model in an Urban Climate Model and its Application
Authors: Jin Luxi , Schubert Sebastian , Fenner Daniel , Meier Fred , Schneider Christoph 
Published: September 2020

AbstractWe report the ability of an urban canopy model, coupled with a regional climate model, to simulate energy fluxes, the intra-urban variability of air temperature, urban-heat-island characteristics, indoor temperature variation, as well as anthropogenic heat emissions, in Berlin, Germany. A building energy model is implemented into the Double Canyon Effect Parametrization, which is coupled with the mesoscale climate model COSMO-CLM (COnsortium for Small-scale MOdelling in CLimate Mode) and takes into account heat generation within buildings and calculates the heat transfer between buildings and the urban atmosphere. The enhanced coupled urban model is applied in two simulations of 24-day duration for a winter and a summer period in 2018 in Berlin, using downscaled reanalysis data to a final grid spacing of 1 km. Model results are evaluated with observations of radiative and turbulent energy fluxes, 2-m air temperature, and indoor air temperature. The evaluation indicates that the improved model reproduces the diurnal characteristics of the observed turbulent heat fluxes, and considerably improves the simulated 2-m air temperature and urban heat island in winter, compared with the simulation without the building energy model. Our set-up also estimates the spatio–temporal variation of wintertime energy consumption due to heating with canyon geometry. The potential to save energy due to the urban heat island only becomes evident when comparing a suburban site with an urban site after applying the same grid-cell values for building and street widths. In summer, the model realistically reproduces the indoor air temperature and its temporal variation.
Efficacy of left atrial plication for atrial functional mitral regurgitation
Authors: Matsumori Masamichi , Kawashima Motoharu , Aihara Takamitsu , Fujisue Jun , Fujimoto Masato , Fukase Keigo , Nomura Yoshikatsu , Tanaka Hiroshi , Murakami Hirohisa , Mukohara Nobuhiko 
Published: September 2020

Abstract
Objective
Atrial functional mitral regurgitation (AFMR) is caused by atrial fibrillation and left atrial enlargement. Our study aimed to evaluate the efficacy of left atrial plication (LAP) for AFMR.

Methods
Of 1164 mitral valve surgery patients at our hospital from January 2000 to May 2019, 22 patients underwent surgery for AFMR. Our retrospective analysis divided the patients with AFMR into two groups according to whether LAP was performed (LAP + group, n = 9; LAP − group, n = 13). Mitral valve angle (MV angle) (horizontal inclination of mitral valve) was measured by pre- and post-operative computed tomography scan. Individuals with type II mitral regurgitation, left ventricular ejection fraction of < 55%, males with left ventricular endo-diastolic dimension of > 60 mm and females with > 55 mm, aortic valve disease, mitral valve calcification, hypertrophic obstructive cardiomyopathy, and both “redo” and emergency cases were excluded.

Result
Mitral valve replacement was performed in 6 patients and mitral ring annuloplasty in 16 cases. No recurrence of mitral regurgitation or structural valve deterioration occurred during the follow-up period. There were no hospital deaths; 3 deaths occurred during the follow-up period. Compared to the LAP − group, the LAP + group demonstrated a significantly greater decrease of MV angle (16.6 ± 8.1° vs. 1.2 ± 6.9°, p < 0.01) and left atrial dimension (18.4 ± 7.0 mm vs. 6.9 ± 14.6 mm, p = 0.02).

Conclusions
Surgical results of AFMR were satisfactory. LAP may be appropriate for correcting the angle of a mitral valve tilted horizontally. More cases need to be considered in the future.
The effect of nanoparticles on reservoir wettability alteration: a critical review
Authors: Eltoum Hilmy , Yang Yu-Long , Hou Ji-Rui 
Published: September 2020

AbstractA novel concept of treating oil reservoirs by nanofluids is being developed to improve oil recovery and reduce the trapped oil in hydrocarbon reservoirs. Nanoparticles show great potential in enhancing oil recovery under ambient conditions. In this paper, the approaches of wettability alteration by using nanofluid, stability of nanofluids, and the most reliable wettability alteration mechanisms associated with variant types of nanoparticles have been reviewed. Moreover, the parameters that have a significant influence on nanofluid flooding have been discussed. Finally, the recent studies of the effect of nanoparticles on wettability alteration have been summarised and analysed. Furthermore, this paper presents possible opportunities and challenges regarding wettability alteration using nanofluids.
Intuitions About the Reference of Proper Names: a Meta-Analysis
Authors: van Dongen Noah , Colombo Matteo , Romero Felipe , Sprenger Jan 
Published: September 2020

AbstractThe finding that intuitions about the reference of proper names vary cross-culturally (Machery et al. Cognition 92: 1–12. 2004) was one of the early milestones in experimental philosophy. Many follow-up studies investigated the scope and magnitude of such cross-cultural effects, but our paper provides the first systematic meta-analysis of studies replicating (Machery et al. Cognition 92: 1–12. 2004). In the light of our results, we assess the existence and significance of cross-cultural effects for intuitions about the reference of proper names.
A Survey on Learning-Based Robotic Grasping
Authors: Kleeberger Kilian , Bormann Richard , Kraus Werner , Huber Marco F. 
Published: September 2020

AbstractPurpose of ReviewThis review provides a comprehensive overview of machine learning approaches for vision-based robotic grasping and manipulation. Current trends and developments as well as various criteria for categorization of approaches are provided.Recent FindingsModel-free approaches are attractive due to their generalization capabilities to novel objects, but are mostly limited to top-down grasps and do not allow a precise object placement which can limit their applicability. In contrast, model-based methods allow a precise placement and aim for an automatic configuration without any human intervention to enable a fast and easy deployment.SummaryBoth approaches to robotic grasping and manipulation with and without object-specific knowledge are discussed. Due to the large amount of data required to train AI-based approaches, simulations are an attractive choice for robot learning. This article also gives an overview of techniques and achievements in transfers from simulations to the real world.
Global Patterns of Recent Mass Movement on Asteroid (101955) Bennu
Authors: Jawin E. R. , Walsh K. J. , Barnouin O. S. , McCoy T. J. , Ballouz R.‐L. , DellaGiustina D. N. , Connolly H. C. , Marshall J. , Beddingfield C. , Nolan M. C. , Molaro J. L. , Bennett C. A. , Scheeres D. J. , Daly M. G. , Al Asad M. , Daly R. T. , Bierhaus E. B. , Susorney H. C. M. , Kaplan H. H. , Enos H. L. , Lauretta D. S. 
Published: September 2020

AbstractThe exploration of near‐Earth asteroids has revealed dynamic surfaces characterized by mobile, unconsolidated material that responds to local geophysical gradients, resulting in distinct morphologies and boulder distributions. The OSIRIS‐REx (Origins, Spectral Interpretation, Resource Identification, and Security‐Regolith Explorer) mission confirmed that asteroid (101955) Bennu is a rubble pile with an unconsolidated surface dominated by boulders. In this work, we documented morphologies indicative of mass movement on Bennu and assessed the relationship to slope and other geologic features on the surface. We found globally distributed morphologic evidence of mass movement on Bennu up to ~70° latitude and on spatial scales ranging from individual boulders (meter scale) to a single debris flow ~100 m long and several meters thick. The apparent direction of mass movement is consistent with the local downslope direction and dominantly moves from the midlatitudes toward the equator. Mass movement appears to have altered the surface expression of large (≥30m diameter) boulders, excavating them in the midlatitudes and burying them in the equatorial region. Up to a 10 ± 1 m depth of material may have been transported away from the midlatitudes, which would have deposited a layer ~5 ± 1 m thick in the equatorial region assuming a stagnated flow model. This mass movement could explain the observed paucity of small (<50‐m diameter) craters and may have contributed material to Bennu's equatorial ridge. Models of changes in slope suggest that the midlatitude mass movement occurred in the past several hundred thousand years in regions that became steeper by several degrees.
Australian Social Work Research: An Empirical Study of Engagement and Impact
Authors: Tilbury Clare , Bigby Christine , Fisher Mike , Hughes Mark 
Published: September 2020

Abstract
Internationally, non-academic research impact is assessed by governments as part of evaluating the quality of publicly funded research. A case study method was used to investigate the non-academic impact of Australian social work research. Interviews were conducted with fifteen leading researchers about outputs (research products, such as publications and reports), engagement (interaction between researchers and end-users outside academia to transfer knowledge, methods or resources) and impact (social or economic contributions of research). Twelve case studies were prepared using a standardised template. Content analysis highlighted examples of impact, and theoretical and in vivo coding uncovered processes of engagement and impact. Different types of engagements with research end-users influenced impact in three areas: legislation and policy; practices and service delivery; and quality of life of community members. Engagement and impact were intertwined as research altered policy discourses and illuminated hidden social issues, preparing ground for subsequent, more direct impact. Likewise, academic and non-academic impacts were intertwined as research rigour and academic credibility were perceived to leverage influence. There was no evidence of achieving impact simply through the trickle-down effect of scholarly publication. The findings broaden understandings of how research influences policy and practice and iterative and indirect relationships between engagement and impact.
Preschool autism services: A tale of two Canadian provinces and the implications for policy
Authors: Smith Isabel M , Waddell Charlotte , Ungar Wendy J , den Otter Jeffrey , Murray Patricia , Vezina Francine , D’Entremont Barbara , Flanagan Helen E , Garon Nancy 
Published: September 2020

Abstract
For children with autism spectrum disorder (ASD), a lifelong neurodevelopmental condition, assessment and treatment services vary widely across Canada—potentially creating inequities. To highlight this, the Preschool Autism Treatment Impact study compared children’s services and outcomes in New Brunswick (NB) and Nova Scotia (NS). Diagnostic practices, service delivery models, wait times, and treatment approaches differed, as did children’s 1-year outcomes and costs for families and the public sector. Considering NB and NS strengths, we suggest that an optimal system would include: rapid access to high-quality diagnostic and intervention services; adherence to research-informed practice guidelines; interventions to enhance parents’ skills and self-efficacy; and measures to minimize financial burdens for families. Our results also suggest that provinces/territories must do more to ensure equitable access to effective services, including sharing and reporting on national comparative data. Canadian children with ASD deserve access to effective and consistent services, no matter where they live.
VIII Renaissance Drama: Excluding Shakespeare
Authors: McEvilla Joshua , Wilkinson Kate , Cryar Jennifer Jenny , Ragni Cristiano , Equestri Alice 
Published: September 2020

AbstractThis chapter has three sections: 1. Editions and Textual Matters; 2. Theatre History; 3. Criticism. Section 1 is by Joshua McEvilla; section 2 is by Kate Wilkinson; section 3(a) is by Jennifer Cryar; section 3(b) is by Cristiano Ragni; section 3(c) is by Alice Equestri.
Retention Strategies for Medications for Opioid Use Disorder in Adults: A Rapid Evidence Review
Authors: Chan Brian , Gean Emily , Arkhipova-Jenkins Irina , Gilbert Jennifer , Hilgart Jennifer , Fiordalisi Celia , Hubbard Kimberly , Brandt Irene , Stoeger Elizabeth , Paynter Robin , Korthuis Philip Todd , Guise Jeanne-Marie 
Published: September 2020

Objectives:
Although medications for opioid use disorder (MOUD) save lives, treatment retention remains challenging. Identification of interventions to improve MOUD retention is of interest to policymakers and researchers. On behalf of the Agency for Healthcare Research and Quality, we conducted a rapid evidence review on interventions to improve MOUD retention.

Methods:
We searched MEDLINE and the Cochrane Library from February 2009 through August 2019 for systematic reviews and randomized trials of care settings, services, logistical support, contingency management, health information technology (IT), extended-release (XR) formulations, and psychosocial interventions that assessed retention at least 3 months.

Results:
Two systematic reviews and 39 primary studies were included; most did not focus on retention as the primary outcome. Initiating MOUD in soon-to-be-released incarcerated people improved retention following release. Contingency management may improve retention using antagonist but not agonist MOUD. Retention with interventions integrating medical, psychiatric, social services, or IT did not differ from in-person treatment-as-usual approaches. Retention was comparable with XR- compared to daily buprenorphine formulations and conflicting with XR-naltrexone monthly injection compared to daily buprenorphine. Most psychosocial interventions did not improve retention.

Discussion:
Consistent but sparse evidence supports criminal justice prerelease MOUD initiation, and contingency management interventions for antagonist MOUD. Integrating MOUD with medical, psychiatric, social services, delivering through IT, or administering via XR-MOUD formulations did not worsen retention. Fewer than half of the studies we identified focused on retention as a primary outcome. Studies used different measures of retention, making it difficult to compare effectiveness. Additional inquiry into the causes of low retention would inform future interventions.
Registration: PROSPERO: CRD42019134739
Neonatal Sepsis
Authors: Glaser Margaret A. , Hughes Lauren M. , Jnah Amy , Newberry Desi 
Published: September 2020

Background:
Early-onset sepsis, occurring within 72 hours of birth, and late-onset sepsis, occurring after this time period, present serious risks for neonates. While culture-based screening and intrapartum antibiotics have decreased the number of early-onset cases, sepsis remains a top cause of neonatal morbidity and mortality in the United States.

Purpose:
To provide a review of neonatal sepsis by identifying its associated risk factors and most common causative pathogens, reviewing features of the term and preterm neonatal immune systems that increase vulnerability to infection, describing previous and the most current management recommendations, and discussing relevant implications for the neonatal nurse and novice neonatal nurse practitioner.

Methods/Search Strategy:
An integrative review of literature was conducted using key words in CINAHL, Google Scholar, and PubMed.

Findings/Results:
Group B streptococcus and Escherichia coli are the most common pathogens in early-onset sepsis, while Coagulase–negative staphylococci comprise the majority of cases in late-onset. The neonatal immune system is vulnerable due to characteristics including decreased cellular activity, underdeveloped complement systems, preferential anti-inflammatory responses, and insufficient pathogenic memory. Blood cultures remain the criterion standard of diagnosis, with several other adjunct tests under investigation for clinical use. The recent development of the sepsis calculator has been a useful tool in the management of early-onset cases.

Implications for Practice:
It is vital to understand the mechanisms behind the neonate's elevated risk for infection and to implement evidence-based management.

Implications for Research:
Research needs exist for diagnostic methods that deliver timely and sensitive results. A tool similar to the sepsis calculator does not exist for preterm infants or late-onset sepsis, groups for which antibiotic stewardship is not as well practiced.

Video Abstract available at
https://journals.lww.com/advancesinneonatalcare/Pages/videogallery.aspx?autoPlay=false&videoId=40
What Is the Long-Term Impact of an Implant Stewardship Program on Orthopaedic Trauma Implant Pricing?
Authors: Morellato John , O'Hara Nathan N. , Baker Mitchell , O'Toole Robert V. , Pollak Andrew N. 
Published: September 2020

Objectives:
To analyze the effectiveness of an implant stewardship program on implant cost containment and to estimate surgeons' responsiveness to implant price changes.

Design:
Interrupted time series.

Setting:
Level I trauma center.

Patients/Participants:
Monitored usage of 5 trauma constructs by 10 surgeons over a 5-year period.

Intervention:
Red-Yellow-Green (RYG) implant pricing comparison chart.

Main Outcome Measurements:
Primary outcomes were changes in the mean price, minimum price, and the number of price changes. The secondary outcome was surgeons' responsiveness to RYG/cost changes.

Results:
The study consisted of 2468 procedures. A mean construct price decrease of $66 per year [95% confidence interval (CI), $−170 to $−151], with distal femoral plates demonstrating the largest mean annual price decline ($486; 95% CI, $−540 to $−432). The minimum construct price decreased by $131 per year (95% CI, $−155 to $−111), with the largest reductions observed for distal femoral plates (−$436 per year; 95% CI, $−516 to $−354) and external fixators (−$122 per year; 95% CI, $−258 to $−136). The median price decrease was $407 (range: $6 to $2491) or 12.5% of the previous price. Positive changes in RYG levels increased surgeons' usage of tibial nails by 115%, femoral nails by 106%, and external fixators by 104%. Surgeons' implant selection was insensitive to RYG changes for distal femoral plates [RYG elasticity (E

RYG
): −0.74] and proximal tibia plates (E

RYG
: −0.21).

Conclusions:
The implant stewardship program was associated with substantial implant price reductions. Surgeons' implant selection was especially sensitive to price changes for intramedullary nails and external fixators.
Effects of Restoration of Sagittal Alignment on Adjacent Segment Degeneration in Instrumented Lumbar Fusions
Authors: Kim Sang-Il , Min Hyung-Ki , Ha Kee-Yong , Park Hyung-Youl , Cho Chang-Hee , Cho Ryu-Kyoung , Kim Young-Hoon 
Published: September 2020

Study Design.
Retrospective case-control study.

Objective.
To investigate the effects of postoperative sagittal alignment on radiographic adjacent segment degeneration (ASD) after lumbar fusion surgery.

Summary of Background Data.
ASD is one of inherent problems with fusion surgery. Many confounding factors are related to the development of ASD. Recently, sagittal alignment has been emphasized for its significance on ASD.

Methods.
Seventy-three patients who underwent four-level lumbar fusion surgery (L2–S1) were divided into two groups according to postoperative sagittal alignment (pelvic incidence–lumbar lordosis [PI–LL] ≥ or <9°): 44 patients (matched group, including 10 patients who underwent pedicle subtraction osteotomy [PSO] at L4) and 29 patients (mismatched group). The general demographics, radiographic parameters, and clinical outcomes were recorded. Preoperative disc degeneration at L1–2 was evaluated by Pfirrmann grade and Kellgren-Lawrence (K-L) grade. Disc degeneration at L1–2 was evaluated by the K-L grade on 2-year postoperative X-rays.

Results.
The incidence of radiographic ASD (11 [25%] vs. 16 patients [55%], P = 0.02) and Oswestry Disability Index (ODI) scores (36.9 ± 19.9 vs. 49.4 ± 20.7, P = 0.015) at postoperative 2 years were significantly higher in the mismatched group. There were no significant differences in other demographic and radiographic parameters between the two groups. On subgroup analysis between 10 PSO patients and the mismatched group, the mismatched group showed a higher incidence of radiographic ASD (16 [55%] vs. 1 patient [10%], P = 0.041) and worse ODI scores (49.7 ± 20.5 vs. 39.0 ± 20.7, P = 0.040). Preoperative Pfirrmann grade at L1–2 (odds ratio [OR] = 4.191, 95% confidence interval [CI]: 1.754–10.013, P = 0.001) and postoperative PI–LL mismatch (OR = 4.890, 95% CI: 1.550–15.427, P = 0.007) showed significant relationships with the development of radiographic ASD at postoperative 2 years.

Conclusion.
The restoration of optimal sagittal alignment, even with PSO, may provide a protective effect on the development of radiographic ASD, although the preoperative disc degeneration grade was a risk factor for radiographic ASD.

Level of Evidence: 3