bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Drop Angle Variation and Restraint Mechanisms on Surface Mount Electronics Under High G Shock
Authors: Lall Pradeep , Pandurangan Aathi Raja Ram , Dornala Venkata Kalyan Reddy , Suhling Jeff , Deep John , Lowe Ryan 
Published: December 2019

Abstract
Defense and Aerospace applications increasingly rely on commercial off-the shelf electronics. Electronics in defense applications may be exposed to harsh environments including high-g acceleration loads. The horizontal board configuration is most frequently tested. However, other shock orientations may be more damaging depending on technology and design. The out-of-plane displacement and strain values highly depend on the angle of shock on the electronic components in the printed circuit board. The effect of variation in drop angle under high G conditions, and efficacy of supplemental restraint mechanisms on the reliability have not been studied at high-g acceleration loads in the range of 10,000g–50,000g. In this study the reliability of fine-pitch electronics and large 3640 capacitors with C0G dielectric has been studied in presence of potting compounds, different shock orientations. A circular printed circuit board has been designed with daisy-chained packages. The drop angle has been varied from zero-degree to 30-degree. A drop-tower with dual mass shock amplifier has been used to achieve the desired acceleration pulse. Transient dynamic deformation has been measured using high-speed imaging in conjunction with digital image correlation.
Evaluation of the efficacy and safety of text messages targeting adherence to cardiovascular medications in secondary prevention: the txt2heart Colombia randomised controlled trial protocol
Authors: Bermon Anderson , Uribe-Rodríguez Ana Fernanda , Pérez-Rivero Paula Fernanda , Prieto-Merino David , Cáceres Rivera Diana Isabel , Guio Elizabeth , Atkins Louise , Horne Robert , Murray Elizabeth , Serrano Díaz Norma Cecilia , Free Caroline , Perel Pablo , Casas Juan P 
Published: December 2019

IntroductionAnti-platelet therapy, angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers, beta-blockers and statins are cost-effective in patients with atherosclerotic cardiovascular diseases (ASCVD) for reducing the risk of ASCVD events. Unfortunately, there is abundant evidence that adherence to these cardiovascular medications is far from ideal. A recent Cochrane review showed a potential beneficial effect of Short Message Service (SMS) interventions on adherence to medication in ASCVD patients.Methods and analysisThe txt2heart study is a pragmatic randomised single-blind controlled trial. The objective is to evaluate the efficacy and safety of an intervention with SMS messages delivered by mobile phones to improve adherence to cardiovascular medications in patients with ASCVD. The intervention consists of behavioural techniques delivered via SMS. The primary outcome is change in blood serum low-density lipoprotein cholesterol levels as an indicator of adherence to statins. Secondary outcomes will include systolic blood pressure as an indicator of adherence to blood-lowering therapies and heart rate as an indicator of adherence to beta-blockers, urine levels of11-dehydrothromboxane B2, self-reported adherence to cardiovascular medications and rates of cardiovascular death or hospitalisation due to cardiovascular disease.Ethics and disseminationThe study will be performed in compliance with the protocol, regulatory requirements, Good Clinical Practice and ethical principles of the Declaration of Helsinki. The Ethics Committee of Fundación Cardiovascular de Colombia evaluated and approved the trial. The txt2heart Colombia trial aims to provide robust evidence to evaluate whether SMS messages delivered through mobile telephones change the behaviour of Colombian patients who have suffered a cardiovascular event. Trial results will be presented to the local health authorities, and if the intervention is effective and safe, we hope this strategy will be implemented quickly because of its low cost and wide-reaching impact on the population.Trial registration numberNCT03098186.
Use of smartphones for detecting diabetic retinopathy: a protocol for a scoping review of diagnostic test accuracy studies
Authors: Tan Choon Han , Quah Willie-Henri , Tan Colin S H , Smith Helen , Tudor Car Lorainne 
Published: December 2019

IntroductionDiabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus and the leading cause of impaired vision in adults worldwide. Early detection and treatment for DR could improve patient outcomes. Traditional methods of detecting DR include the gold standard Early Treatment Diabetic Retinopathy Study seven standard fields fundus photography, ophthalmoscopy and slit-lamp biomicroscopy. These modalities can be expensive, difficult to access and require involvement of specialised healthcare professionals. With the development of mobile phone technology, there is a growing interest in their use for DR identification as this approach is potentially more affordable, accessible and easier to use. Smartphones can be employed in a variety of ways for ophthalmoscopy including the use of smartphone camera, various attachments and artificial intelligence for obtaining and grading of retinal images. The aim of this scoping review is to determine the diagnostic test accuracy of various smartphone ophthalmoscopy approaches for detecting DR in diabetic patients.Methods and analysisWe will perform an electronic search of MEDLINE, Embase and Cochrane Library for literature published from 2000 onwards. Two reviewers will independently analyse studies for eligibility and assess study quality using the QUADAS-2 tool. Data for a 2⨉2 contingency table will be extracted. If possible, we will pool sensitivity and specificity data using the random-effects model and construct a summary receiver operating characteristic curve. In case of high heterogeneity, we will present the findings narratively. Subgroup analysis and sensitivity analysis will be performed where appropriate.Ethics and disseminationThis scoping review aims to provide an overview of smartphone ophthalmoscopy in DR identification. It will present findings on the accuracy of smartphone ophthalmoscopy in detecting DR, identify gaps in the literature and provide recommendations for future research. This review does not require ethical approval as we will not collect primary data.
Efficacy of a web-based self-help tool to reduce problem gambling in Switzerland: study protocol of a two-armed randomised controlled trial
Authors: Baumgartner Christian , Bilevicius Elena , Khazaal Yasser , Achab Sophia , Schaaf Susanne , Wenger Andreas , Haug Severin , Keough Matthew , Hodgins David , Schaub Michael P 
Published: December 2019

IntroductionThe past-year prevalence of problem gambling worldwide averages 2.3%. Switzerland exhibits a slightly lower past-year prevalence rate, of 1.1%, among adults. Only a minority of these adults attend outpatient treatment. Surveyed problem gamblers have explained that they wanted to handle the problem on their own. The option of a web-based self-help programme could potentially reach those users who hesitate to approach treatment centres and help them to reduce or stop their problem gambling. The effectiveness of such web-based interventions has been shown in other countries.Methods and analysisThis two-armed randomised controlled trial (RCT) will examine the efficacy of a web-based self-help intervention, relative to an active control condition with a self-help manual, at reducing problem gambling. The active intervention programme, spanning 8 weeks, consists of nine modules developed to reduce gambling and attenuate psychopathological comorbidity, including depression, anxiety and stress-related disorder symptoms, relying on motivational interviewing and cognitive behavioural therapy. With a target sample size of 352, questionnaire data will be collected at baseline, and at 8 and 24 weeks after baseline. Primary outcomes will be the number of days one has gambled in the last 30 days. Secondary outcomes will include money and time spent on gambling activities, changes in gambling-related problems (Problem Gambling Severity Index, Gambling Symptom Assessment Scale), use of alcohol and cigarettes, and psychopathological comorbidity. All data analysis will comply with the intention-to-treat principle.Ethics and disseminationThe RCT will be conducted in accordance with the Declaration of Helsinki; the consort eHealth Guidelines for studies on medical devices; the European Directive on medical devices 93/42/EEC, Swiss Law and Swiss Regulatory Authority requirements. The study was approved by the ethics committee of the Canton of Zurich. Results will be published in a scientific peer-reviewed journal. Participants will be informed via e-mail about study results via a lay-person-friendly summary of trial findings.Trial registration numberCurrent Controlled Trials registry (ISRCTN16339434).
Concomitant intraperitoneal and systemic chemotherapy for extensive peritoneal metastases of colorectal origin: protocol of the multicentre, open-label, phase I, dose-escalation INTERACT trial
Authors: de Boer Nadine Leonie , Brandt-Kerkhof Alexandra R M , Madsen Eva V E , Diepeveen Marjolein , van Meerten Esther , van Eerden Ruben A G , de Man Femke M , Bouamar Rachida , Koolen Stijn L W , de Hingh Ignace H J T , Bakkers Checca , Rovers Koen P , Creemers Geert-Jan M , Deenen Maarten J , Kranenburg Onno W , Constantinides Alexander , Mathijssen Ron H J , Verhoef Cornelis , Burger Jacobus W A ,   Dutch Peritoneal Oncology Group (DPOG)
Published: December 2019

IntroductionCytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) has become standard of care for patients with peritoneal metastases of colorectal origin with a low/moderate abdominal disease load. In case of a peritoneal cancer index (PCI) score >20, CRS-HIPEC is not considered to be beneficial. Patients with a PCI >20 are currently offered palliative systemic chemotherapy. Previous studies have shown that systemic chemotherapy is less effective against peritoneal metastases than it is against haematogenous spread of colorectal cancer. It is suggested that patients with peritoneal metastases may benefit from the addition of intraperitoneal chemotherapy to systemic chemotherapy. Aim of this study is to establish the maximum tolerated dose of intraperitoneal irinotecan, added to standard of care systemic therapy for colorectal cancer. Secondary endpoints are to determine the safety and feasibility of this treatment and to establish the pharmacokinetic profile of intraperitoneally administered irinotecan.Methods and analysisThis phase I, ‘3+3’ dose-escalation, study is performed in two Dutch tertiary referral centres. The study population consists of adult patients with extensive peritoneal metastases of colorectal origin who have a good performance status and no extra-abdominal metastases. According to standard work-up for CRS-HIPEC, patients will undergo a diagnostic laparoscopy to score the PCI. In case of a PCI >20, a peritoneal access port will be placed in the abdomen of the patient. Through this port we will administer intraperitoneal irinotecan, in combination with standard systemic treatment consisting of 5-fluorouracil/leucovorin with oxaliplatin and the targeted agent bevacizumab. Therapy consists of a maximum of 12 cycles 2-weekly.Ethics and disseminationThis study protocol is approved by a research medical ethics committee (Rotterdam, Netherlands) and the Dutch Competent Authority (CCMO, The Hague, Netherlands). The results of this trial will be submitted for publication in a peer-reviewed scientific journal.Trail registration numberNL6988 and NL2018-000479-33; Pre-results.
Effect of gluon condensate on light quark energy loss
Authors: Zhang Zi-qiang 
Published: December 2019

AbstractApplying the AdS/CFT correspondence, we study the jet quenching of light quarks traversing in a deformed AdS background with backreaction due to the gluon condensate. We perform the analysis using the falling string and shooting string cases, respectively. It is found that the two methods lead to a unanimous conclusion: the inclusion of the gluon condensate enhances the energy loss. In particular, the energy loss decreases as the value of the gluon condensate decreases in the deconfined phase, and at high temperature, it is nearly not modified by the gluon condensate, in agreement with the findings of the jet quenching parameter and drag force.
Analogue Hawking radiation and quantum soliton evaporation in a superconducting circuit
Authors: Tian Zehua , Du Jiangfeng 
Published: December 2019

AbstractHawking radiation is one of the most intriguing and elusive predictions of quantum field theory in curved spacetime. Previous works simulating Hawking radiation have been mostly based on Unruh’s scenario, where the propagation of quantum field in classical gravitational background is mimicked. Here, guided by the duality between black holes in Jackiw-Teitelboim (JT) dilaton gravity and solitons in sine-Gordon (SG) field theory, we propose the use of a superconducting circuit for investigating analogue Hawking radiation. $$1+1$$1+1 dimensional black holes can be realized as solitons of the SG equation of superconducting phase. It is found despite the absence of field theoretic dynamical modes, the analogue Hawking radiation is emitted in terms of the quantum soliton evaporation as a result of quantum perturbation of the black hole metric. Our theoretical proposal could not only facilitate the observation of relativistic quantum effects in lab, but also contribute to experimentally exploring the quantum mechanics of solitons, especially to the deep relationship between such mechanics and black hole physics.
New five-dimensional Bianchi type magnetically charged hairy topological black hole solutions in string theory
Authors: Naderi F. , Rezaei-Aghdam A. 
Published: December 2019

AbstractWe construct black hole solutions to the leading order of string effective action in five dimensions with the source given by dilaton and magnetically charged antisymmetric gauge B-field. Presence of the considered B-field leads to the unusual asymptotic behavior of the solutions which are neither asymptotically flat nor asymptotically (A)dS. We consider the three-dimensional space part to correspond to the Bianchi classes and so the horizons of these topological black hole solutions are modeled by seven homogeneous Thurston’s geometries of $$E^3$$E3, $$S^3$$S3, $$H^3$$H3, $$ H^2 \times E^1$$H2×E1, $$\widetilde{{SL_2R}}$$SL2R~, nilgeometry, and solvegeometry. Calculating the quasi-local mass, temperature, entropy, dilaton charge, and magnetic potential, we show that the first law of black hole thermodynamics is satisfied by these quantities and the dilaton charge is not independent of mass and magnetic charge. Furthermore, for Bianchi type V, the T-dual black hole solution is obtained which carries no charge associated with B-field and the entropy turns to be invariant under the T-duality.
A hint towards mass dimension one Flag-dipole spinors
Authors: Rogerio R. J. Bueno , Villalobos C. H. Coronado , Aguirre A. R. 
Published: December 2019

AbstractIn this report we advance in exploring further details concerning the formal aspects of the construction of a Flag-dipole spinor. We report a (re-)definition of the dual structure which provide a Lorentz invariant and non-null norm, ensuring a local theory. With the new dual structure at hands, we look towards define relevant physical amounts, e.g., spin sums and quantum field operator. As we will see, the Flag-dipole and the Elko’s theory are quite familiar. In this vein, it is possible, via a matrix transformation, to write Flag-dipole spinors in terms of Elko spinor, evincing that both spinors are physically related and some physical amounts may be stated as equivalent.
Superalgebras with superinvolution or graded involution with colengths sequence bounded by 3
Authors: Ioppolo Antonio 
Published: December 2019

Let [Formula: see text] be a superalgebra with superinvolution or graded involution over a field of characteristic zero and let [Formula: see text], [Formula: see text], be the [Formula: see text]-cocharacter of [Formula: see text]. The ∗-colengths sequence, [Formula: see text], [Formula: see text], is the sum of the multiplicities in the decomposition of the [Formula: see text]-cocharacter [Formula: see text], for all [Formula: see text]. The main purpose of this paper is to classify the superalgebras with superinvolution with ∗-colengths sequence bounded by three. Moreover, we shall extend to the general case, the analogous result proved by do Nascimento and Vieira in [Superalgebras with graded involution and star-graded colength bounded by 3, Linear Multilinear Algebra 67(10) (2019) 1999–2020] for finite-dimensional superalgebras with graded involution.
Temporal Trends and Site Variation in High‐Risk Coronary Intervention and the Use of Mechanical Circulatory Support: Insights From the Veterans Affairs Clinical Assessment Reporting and Tracking (CART) Program
Authors: Bricker Rory S. , Glorioso Thomas J. , Jawaid Omar , Plomondon Mary E. , Valle Javier A. , Armstrong Ehrin J. , Waldo Stephen W. 
Published: December 2019

Background

Patients undergoing percutaneous coronary intervention (
PCI
) are older with greater medical comorbidities and anatomical complexity than ever before, resulting in an increased frequency of nonemergent high‐risk
PCI
(
HR
‐
PCI
). We thus sought to evaluate the temporal trends in performance of
HR
‐
PCI
and utilization of mechanical circulatory support in the largest integrated healthcare system in the United States.

Methods and Results

A cohort of high‐risk adult patients that underwent nonemergent
PCI
in the Veterans Affairs Healthcare System between January 2008 and June 2018 were identified by objective clinical, hemodynamic, and anatomic criteria. Temporal trends in the performance of
HR
‐
PCI
, utilization of mechanical circulatory support, and site‐level variation were assessed. Of 111 548 patients assessed during the study period, 554 met 3 high‐risk criteria whereas 4414 met at least 2 criteria for
HR
‐
PCI
. There was a significant linear increase in the proportion of interventions that met 3 (
P
<0.001) or at least 2 (
P
<0.001) high‐risk criteria over time, with rates approaching 1.9% and 11.2% in the last full calendar year analyzed. A minority of patients who met all high‐risk criteria received
PCI
with mechanical support (15.7%) without a significant increase over time (
P
=0.193). However, there was significant site‐level variation in the probability of performing
HR
‐
PCI
(4.0‐fold higher likelihood) and utilizing mechanical circulatory support (1.9‐fold higher likelihood) between high and low utilization sites.

Conclusions

The proportion of cases categorized as
HR
‐
PCI
has increased over time, with significant site‐level variation in performance. The majority of
HR
‐
PCI
cases did not utilize mechanical support, highlighting a discrepancy between current recommendations and clinical practice in an integrated healthcare system.
Rupture Risk of Small Unruptured Intracranial Aneurysms in Japanese Adults
Authors: Suzuki Takashi , Takao Hiroyuki , Rapaka Saikiran , Fujimura Soichiro , Ioan Nita Cosmin , Uchiyama Yuya , Ohno Hiroshi , Otani Katharina , Dahmani Chihebeddine , Mihalef Viorel , Sharma Puneet , Mohamed Ashraf , Redel Thomas , Ishibashi Toshihiro , Yamamoto Makoto , Murayama Yuichi 
Published: December 2019

Background and Purpose—
Therapeutic decision making for small unruptured intracranial aneurysms (<10 mm) is difficult. We aimed to develop a rupture risk model for small intracranial aneurysms in Japanese adults, including clinical, morphological, and hemodynamic parameters.

Methods—

We analyzed 338 small unruptured aneurysms; 35 ruptured during the observation period, and 303 remained stable. Clinical, morphological, and hemodynamic parameters were considered. Computational fluid dynamics was used to calculate hemodynamic parameters based on computed tomography images of all aneurysms in their unruptured state. Differences between the ruptured and unruptured groups were tested by the Mann-Whitney
U
or Fisher exact tests. Multivariate logistic regression was applied to obtain a rupture risk model. Its predictive ability was investigated by receiver operating characteristic analysis.

Results—

The risk model revealed that rupture may be more likely to in younger patients (odds ratio [OR], 0.92 for each age increase of 1 year [95% CI, 0.88−0.96]
P
<0.001) with multiple aneurysms (OR, 2.58 [95% CI, 1.07−6.19]
P
=0.03), located at a bifurcation (OR, 5.45 [95% CI, 1.87−15.85]
P
=0.002), with a bleb (OR, 4.09 [95% CI, 1.42−11.79]
P
=0.009), larger length (OR, 1.91 for each increase of 1 mm [95% CI, 1.42−2.57]
P
<0.001), and lower pressure loss coefficient (OR, 0.33 for each decrease of 1 unit [95% CI, 0.14−0.77]
P
=0.01). The sensitivity, specificity, and area under the curve were 0.800, 0.752, and 0.826 (95% CI, 0.739−0.914) respectively.

Conclusions—
Younger age, presence of multiple aneurysms, location at a bifurcation, presence of a bleb, larger length, and lower pressure loss coefficient were identified as risk factors for rupture of small intracranial aneurysms. The risk model should be validated in further studies.
Soil nematode communities as indicators of soil health in different land use types in tropical area
Authors: Gao Dandan , Wang Faming , Li Jian , Yu Shiqin , Li Zhian , Zhao Jie 
Published: December 2019

Summary
The study of soil nematode communities is a powerful tool that has been widely used as an indicator of soil health. This study explored whether soil nematode composition of different land use types could be used as a baseline to indicate the soil health of both natural and anthropogenic ecosystems. The soil nematode community compositions were documented for five land use types in tropical China: bare land, secondary forest, old forest, eucalyptus plantation and litchi orchards. The first three land use types are natural ecosystems and considered as a vegetation succession, whereas the other two are anthropogenically managed ecosystems. The vegetation succession from bare land to secondary and old forests increased soil nematode abundance, diversity, diversity-weighted abundance and complexity of community structure. During the wet season, the abundances of the total nematodes, bacterivores, fungivores and herbivores were significantly lower in eucalyptus plantation and litchi orchards than in secondary and old forests, but higher than in bare land. During the dry season, the abundances of the total nematodes and each trophic group were greatest in orchards. The pattern of the diversity-weighted abundance of each nematode trophic group was similar to that of nematode trophic group abundance. The results indicate that soil nematode communities of different land use types could be used for comparison of soil health conditions in natural and managed ecosystems. Particularly, the soil health conditions as indicated through nematode communities of the two managed ecosystems were not as good as those of secondary and old forests, whereas litchi orchards might have better soil health conditions than eucalyptus plantations in tropical China.
Streumer on Non-Cognitivism and Reductivism About Normative Judgement
Authors: Evers Daan 
Published: December 2019

Bart Streumer believes that the following principle is true of all normative judgements:
(A) When two people make conflicting normative judgements, at most one of them is correct. Streumer argues that noncognitivists are unable to explain why (A) is true, or our acceptance of it. I argue that his arguments are inconclusive. I also argue that our acceptance of (A) is limited in the case of instrumental and epistemic normative judgements, and that the extent to which we do accept (A) for such judgements can be explained by an assumption of shared standards of correctness. Finally, I argue that reductivists can appeal to the same ideas to defend their view that instrumental and epistemic normative judgements describe non-normative relations.