bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond counts and averages: Relating geodiversity to dimensions of biodiversity
Authors: Read Quentin D. , Zarnetske Phoebe L. , Record Sydne , Dahlin Kyla M. , Costanza Jennifer K. , Finley Andrew O. , Gaddis Keith D. , Grady John M. , Hobi Martina L. , Latimer Andrew M. , Malone Sparkle L. , Ollinger Scott V. , Pau Stephanie , Wilson Adam M. 
Published: January 2020

AbstractAimWe may be able to buffer biodiversity against the effects of ongoing climate change by prioritizing the protection of habitat with diverse physical features (high geodiversity) associated with ecological and evolutionary mechanisms that maintain high biodiversity. Nonetheless, the relationships between biodiversity and habitat vary with spatial and biological context. In this study, we compare how well habitat geodiversity (spatial variation in abiotic processes and features) and climate explain biodiversity patterns of birds and trees. We also evaluate the consistency of biodiversity–geodiversity relationships across ecoregions.LocationContiguous USA.Time period2007–2016.Taxa studiedBirds and trees.MethodsWe quantified geodiversity with remotely sensed data and generated biodiversity maps from the Forest Inventory and Analysis and Breeding Bird Survey datasets. We fitted multivariate regressions to alpha, beta and gamma diversity, accounting for spatial autocorrelation among Nature Conservancy ecoregions and relationships among taxonomic, phylogenetic and functional biodiversity. We fitted models including climate alone (temperature and precipitation), geodiversity alone (topography, soil and geology) and climate plus geodiversity.ResultsA combination of geodiversity and climate predictor variables fitted most forms of bird and tree biodiversity with < 10% relative error. Models using geodiversity and climate performed better for local (alpha) and regional (gamma) diversity than for turnover‐based (beta) diversity. Among geodiversity predictors, variability of elevation fitted biodiversity best; interestingly, topographically diverse places tended to have higher tree diversity but lower bird diversity.Main conclusionsAlthough climatic predictors tended to have larger individual effects than geodiversity, adding geodiversity improved climate‐only models of biodiversity. Geodiversity was correlated with biodiversity more consistently than with climate across ecoregions, but models tended to have a poor fit in ecoregions held out of the training dataset. Patterns of geodiversity could help to prioritize conservation efforts within ecoregions. However, we need to understand the underlying mechanisms more fully before we can build models transferable across ecoregions.
Community geography as a model for improving efforts of environmental stewardship
Authors: Lopez Christina W. 
Published: January 2020

AbstractEnvironmental stewardship (ES) is an established area of research in numerous fields of study, whereas community geography (CG) is a more recent and growing subfield of geography that aims to build capacity and affect change in communities through university–community partnerships. As such, CG demonstrates a shift in geographic research trends that provide benefits not only to the university but also to the students and community/ies as well. I argue that ES and CG research agendas are characterized by a meaningful overlap and attempts to synthesize them will add value to both bodies of knowledge. This paper overviews both of these research agendas, identifies major challenges and gaps in the extant literature in ES, and suggests how CG can help move the ES research agenda forward. I conclude with the notion that incorporating a CG research approach can (a) better develop the ES literature and (b) provide important benefits for universities, communities, and students who are looking for hands‐on civic engagement experiences.
An innovative method of immersion vacuum cooling for cooked meat products: immersion vacuum cooling with ultrasonic assistance
Authors: Liao Caihu , Yu Yigang 
Published: January 2020

SummaryIn this paper, immersion vacuum cooling with ultrasonic assistance (IVCUA) is compared with immersion vacuum cooling alone (IVC) and vacuum cooling (VC) for cooling time, mass loss, colour, texture profile and water mobility and compartmentalization for cooked meat products. The results reveal that IVCUA clearly enhances the boiling intensity of impregnation liquid compared to IVC. The total cooling time using IVC (126.56 min) for samples from 72 to 4 °C was significantly longer (P < 0.05) than that of IVCUA (96.89 min) and VC (80.48 min). The cooling time of samples from 10 to 4 °C by IVC (46.26 min) was higher (P < 0.05) than that by IVCUA (28.55 min). There were no significant differences (P > 0.05) in mass loss, colour and texture profile among all samples. However, IVCUA had a higher transverse relation time of bulk water (T24) and MRI proton densities (P < 0.05), as well as a more uniform water distribution compared to IVC.
The use of intracardiac echocardiography catheters in endocardial ablation of cardiac arrhythmia: Meta‐analysis of efficiency, effectiveness, and safety outcomes
Authors: Goya Masahiko , Frame Diana , Gache Larry , Ichishima Yoko , Tayar Daiane Oliveira , Goldstein Laura , Lee Stephanie Hsiao Yu 
Published: January 2020

AbstractAimsThe optimal use of intracardiac echocardiography (ICE) may reduce fluoroscopy time and procedural complications during endocardial ablation of cardiac arrhythmias. Due to limited evidence in this area, we conducted the first systematic literature review and meta‐analysis to evaluate outcomes associated with the use of ICE.Methods and ResultsStudies reporting the use of ICE during ablation procedures vs without ICE were searched using PubMed/MEDLINE. A meta‐analysis was performed on the 19 studies (2186 patients) meeting inclusion criteria, collectively representing a broad range of arrhythmia mechanisms. Use of ICE was associated with significant reductions in fluoroscopy time (Hedges' g −1.06; 95% confidence interval [CI] −1.81 to −0.32; P < .01), fluoroscopy dose (Hedges' g −1.27; 95% CI −1.91 to −0.62; P < .01), and procedure time (Hedges' g −0.35; 95% CI −0.64 to −0.05; P = .02) vs ablation without ICE. A 6.95 minute reduction in fluoroscopy time and a 15.2 minute reduction in procedure time was observed between the ICE vs non‐ICE groups. These efficiency gains were not associated with any decreased effectiveness or safety. Sensitivity analyses limiting studies to an atrial fibrillation (AF) only population yielded similar results to the main analysis.ConclusionThe use of ICE in the ablation of cardiac arrhythmias is associated with significantly lower fluoroscopy time, fluoroscopy dose, and shorter procedure time vs ablation without ICE. These efficiency improvements did not compromise the clinical effectiveness or safety of the procedure.
Ethics in contemporary health care management and medical education
Authors: Balak Naci , Broekman Marike L.D. , Mathiesen Tiit 
Published: January 2020

AbstractRationaleThe health care landscape is changing: it has become the largest part of the economy and changes in public management systems will greatly affect how we practice medicine in the future. Medical education will be more important than ever to ensure patients get the best care with empathy. However, new public management systems implemented without thorough analysis might challenge medical education. An increasing number of public health care institutions provide services based on competitive market rules and express their goals in financial terms and have set financial gains as their main goal, which contradicts the fundamental nature of medical ethics and practice.Aims and objectivesTo explore new public management to identify potential problems and offer possible solutions for medical education and health care institutions.MethodsA scoping review of the literature on public administration, hospital management, professionalism, ethics, and medical education was undertaken to map evidence on the topic and identify main concepts and knowledge gaps in the influence of management systems on the quality of medical educational practices.ResultsIf the accelerating changes in public management are cursorily analysed, medical education may lose the esteem in which it has long been held globally. Without precautions, the so‐called new public management medical faculties will—at best—generate economic benefit, following a business model with strict quality rules, regulations, standardized products, and complex analysis and measurement systems. However, these faculties will function at a level far below the ideal of teaching institutions distinguished for their outstanding components, creativity, and ambience.ConclusionsPatients and teaching values are not reducible to financial terms only and the acknowledgement of non‐financial values is fundamental to achieve quality in health care and education. The most essential step could be selecting managers who will implement public management principles while taking into account both business requirements and medical ethics.
Taming the Factor Zoo: A Test of New Factors
Authors: FENG GUANHAO , GIGLIO STEFANO , XIU DACHENG 
Published: January 2020

ABSTRACTWe propose a model selection method to systematically evaluate the contribution to asset pricing of any new factor, above and beyond what a high‐dimensional set of existing factors explains. Our methodology accounts for model selection mistakes that produce a bias due to omitted variables, unlike standard approaches that assume perfect variable selection. We apply our procedure to a set of factors recently discovered in the literature. While most of these new factors are shown to be redundant relative to the existing factors, a few have statistically significant explanatory power beyond the hundreds of factors proposed in the past.
Efficacy of scaffold‐mediated localized chemotherapy in cancer: A systematic review of current research
Authors: Gupta Archana A , Kheur Supriya , Arakeri Gururaj , Thirumal Raj A , Badhe Ravindra V. , Patil Shankargouda , Rao US Vishal , Patil Shekhar , Gomez Ricardo S. , Thomson Peter , Brennan Peter A 
Published: January 2020

AbstractObjectiveTo assess the efficacy of scaffold‐mediated localized chemotherapy in cancer.MethodsDatabases including PubMed, Cochrane Library, and SCOPUS were searched for articles reporting the use of scaffold‐mediated localized drug delivery in cancer. Essential data including scaffold fabrication material and methods, drug dosage and release duration and its effect on the cancer cells were extracted.Results15 articles out of 60 screened, fulfilled the eligibility criteria. Among the 15 studies, 5 studies included only cell lines and 2 studies were on mouse models, while 8 studies involved a combination of cell lines and mouse models. Scaffold materials included both synthetic polymers such as poly‐lactide, polycaprolactone and natural materials including d‐periosteum and human micro‐fragmented adipose tissueA wide number of other variables included the fabrication procedure, drugs used, and the methods used to assess the effects on cancer. As a result, it was not possible to make any direct comparison of the efficacy of the therapeutic strategy used in each of these studies.ConclusionIrrespective of the many variables, a common consensus in all the included studies was that scaffold mediated localized drug delivery effectively reduced cancer cell viability by increasing drug bioavailability to the target tissue, while its localized effect reduced the risk of systemic toxicity.
Preparation, characterization and preliminary pharmacokinetic study of pH-sensitive Hydroxyapatite/Zein nano-drug delivery system for doxorubicin hydrochloride
Authors: Zha Liqiong , Wang Beilei , Qian Jiajia , Fletcher Brock , Zhang Caiyun , Dong Qiannian , Chen Weidong , Hong Lufeng 
Published: January 2020

Abstract

Objectives
Zein nanoparticles (Zein NPs) were used as a hydroxyapatite (HA) biomineralization template to generate HA/Zein NPs. Doxorubicin hydrochloride (DOX) was loaded on HA/Zein NPs (HA/Zein-DOX NPs) to improve its pH-sensitive release, bioavailability and decrease cardiotoxicity.

Methods
HA/Zein-DOX NPs were prepared by phase separation and biomimetic mineralization method. Particle size, polydispersity index (PDI), Zeta potential, transmission electron microscope, X-ray diffraction and Fourier-transform infrared spectroscopy of HA/Zein-DOX NPs were characterized. The nanoparticles were then evaluated in vitro and in vivo.

Key findings
The small PDI and high Zeta potential demonstrated that HA/Zein-DOX NPs were a stable and homogeneous dispersed system and that HA was mineralized on Zein-DOX NPs. HA/Zein-DOX NPs showed pH-sensitive release. Compared with free DOX, HA/Zein-DOX NPs increased cellular uptake which caused 7 times higher in-vitro cytotoxicity in 4T1 cells. Pharmacokinetic experiments indicated the t1/2β and AUC0–t of HA/Zein-DOX NPs were 2.73- and 3.12-fold higher than those of DOX solution, respectively. Tissue distribution exhibited HA/Zein-DOX NPs reduced heart toxicity with lower heart targeting efficiency (18.58%) than that of DOX solution (37.62%).

Conclusion
In this study, HA/Zein-DOX NPs represented an antitumour drug delivery system for DOX in clinical tumour therapy with improved bioavailability and decreased cardiotoxicity.
Belief in Supernatural Evil and Mental Health: Do Secure Attachment to God and Gender Matter?
Authors: Jung Jong Hyun 
Published: January 2020

AbstractThis study examines whether belief in supernatural evil is associated with mental health. In addition, it assesses how secure attachment to God moderates this association and how gender conditions the moderating effect of secure attachment to God. Among a variety of mental health outcomes, this study focuses on general mental health problems as well as anxiety‐related disorders (e.g., general anxiety, social anxiety, and paranoia). Using data from the 2010 Baylor Religion Survey (N = 1,627), the analyses reveal that belief in supernatural evil is positively associated with general anxiety and paranoia. In addition, secure attachment to God buffers the positive associations between belief in supernatural evil and social anxiety and paranoia. Yet, when general mental health problems and general anxiety serve as the outcome measures, secure attachment to God attenuates the positive associations of belief in supernatural evil with mental health only for women, but not men. These results underscore the ways that religious beliefs have both positive and negative implications for mental health. Furthermore, they highlight the importance of gender in the complex relationships between religious beliefs and mental health.
On the Nature of Philosophy
Authors: Žanić Joško 
Published: January 2020

AbstractThis paper claims that what philosophy primarily does is interpret our notions, offer ways of understanding these notions that are not scientific in nature but not contrary to science either. The paper draws a distinction between conceptual analysis, a highly constrained enterprise that is supposed to bring to light what was in the concept all along, and the interpretation of notions, a creative enterprise that offers ways of understanding notions that were not already prefigured by the content of these notions—philosophy consists in the latter, not the former. It explains how these interpretations are justified and what the difference is between better and worse interpretations. The remainder of the paper is organized around three headings: philosophy and science, philosophy and language, and philosophy and progress. It claims that in philosophy there is no real progress, but that philosophy does move forward because the notions at issue are endlessly interpretable.
Emotional regulation training for intensive and critical care nurses
Authors: Kharatzadeh Hamid , Alavi Mousa , Mohammadi Abolfazl , Visentin Denis , Cleary Michelle 
Published: January 2020

AbstractProfessional quality of life is related to psychological well‐being for nurses with implications for quality patient care. This study evaluated the effectiveness of emotional regulation training on depression, anxiety and stress, and professional quality of life for intensive and critical care nurses. In this experimental comparison trial, 60 intensive and critical care nurses were randomly assigned to treatment and wait‐list control groups. The treatment group received six sessions of emotional regulation training, while the wait‐list control group received no treatment. Outcome measures were: the Cognitive Emotion Regulation Questionnaire; the Depression, Anxiety and Stress Scale; and the Professional Quality of Life Scale in a pre‐post design. The treatment group demonstrated greater improvements in burnout and compassion satisfaction compared with the wait‐list control group. No significant reduction in compassion fatigue was found compared with controls. Some cognitive coping strategies improved in the treatment group compared with controls, with greater reductions in depression, anxiety, and stress. This study indicates the benefits of implementing emotional regulation training programs to improve psychological well‐being and professional quality of life for intensive and critical care nurses.
Anodal transcranial direct current stimulation and intermittent theta‐burst stimulation improve deglutition and swallowing reproducibility in elderly patients with dysphagia
Authors: Cosentino Giuseppe , Tassorelli Cristina , Prunetti Paolo , Bertino Giulia , De Icco Roberto , Todisco Massimiliano , Di Marco Salvatore , Brighina Filippo , Schindler Antonio , Rondanelli Mariangela , Fresia Mauro , Mainardi Luca , Restivo Domenico A. , Priori Alberto , Sandrini Giorgio , Alfonsi Enrico 
Published: January 2020

AbstractBackgroundDysphagia in the elderly, known as presbydysphagia, has become a relevant public health problem in several countries. Swallowing disorders may be a consequence of different neurological disorders (secondary presbydysphagia) or the expression of the aging process itself (primary presbydysphagia). We aimed to test the therapeutic potential of two different non‐invasive brain stimulation (NIBS) techniques in subjects with primary or secondary presbydysphagia.MethodsA blinded randomized controlled trial with crossover design was carried out in 42 patients, randomly assigned to anodal transcranial direct current stimulation (tDCS) or intermittent theta‐burst stimulation (TBS) group. Both tDCS and TBS were applied for 5 consecutive days over the right swallowing motor cortex. The swallowing function was assessed before and 1 and 3 months after the stimulation using the Dysphagia Outcome and Severity Scale (DOSS), scored based on clinical assessment and fiberoptic endoscopic evaluation of swallowing. An electrophysiological method was also applied to evaluate changes in the reproducibility of the swallowing behavior.Key ResultsBoth real tDCS and TBS had beneficial effects on the swallowing function in patients with primary and secondary presbydysphagia. Anodal tDCS resulted in an improvement of 0.5 points in DOSS at 1‐month follow‐up (P = .014), whereas intermittent TBS induced an increase of 0.7 and 0.6 points at 1‐ and 3‐month follow‐up evaluations, respectively (P = .0001 and P = .005, respectively). Reproducibility of both the oral and pharyngeal phases of swallowing significantly increased at 1‐month follow‐up.Conclusions and InferencesOur results suggest that non‐invasive cortical stimulation may be useful for dysphagia recovery in elderly patients.
Multiobjective record‐to‐record travel metaheuristic method for solving forest supply chain management problems with economic and environmental objectives
Authors: She Ji , Chung Woodam , Vergara Hector 
Published: January 2020

AbstractMultiobjective optimization is increasingly used to assist decision‐making in forest management when multiple objectives are considered and conflict with each other. Since forest management problems may deal with combinatorial optimization, as the scale of a problem increases, the computation complexity increases exponentially beyond the practical use of exact methods. We propose a multiple‐objective metaheuristic method, referred to as multiobjective record‐to‐record travel (MRRT), to solve such challenging problems. We examined the performance of MRRT and compared it to a mixed integer programming (MIP) optimizer on a forest supply chain multiobjective optimization problem that simultaneously maximizes net revenues and greenhouse gas emission savings from salvage harvest and utilization of beetle‐killed forest stands. Testing on four cases of different problem sizes showed that MRRT performed satisfactorily in approximating the actual Pareto fronts in terms of convergence and coverage, and the distribution of solutions was approximately uniform. The gap between MRRT and MIP solutions increased as the problem size increased. But MRRT produced all solutions within a reasonable computation time, where the computational advantage over MIP was more apparent for large‐scale test cases.Recommendations for Resource Managers

Multiobjective optimization shows trade‐offs among conflicting objectives and assists decision‐making to enhance sustainable forest management.
Multiobjective record‐to‐record travel (MRRT) has a simple algorithm structure and easy parameterization process so that it is adaptable to solve various multiobjective optimization problems.
MRRT produces high‐quality solutions for large‐scale multiobjective optimization problems within a reasonable computation time, which promotes its applicability in practice.
Breeding tepary bean (Phaseolus acutifolius) for drought adaptation: A review
Authors: Mwale Saul Eric , Shimelis Hussein , Mafongoya Paramu , Mashilo Jacob 
Published: January 2020

AbstractTepary bean (Phaseolus acutifolius A. Gray) is a relatively higher drought‐tolerant crop than common bean (P. vulgaris), serving as genetic resource for food and genetic enhancement of related legumes. Tepary bean production is hampered by cultivation of low yielding and abiotic stress‐susceptible cultivars. Targeted selection of agronomic, physiological and biochemical traits that maximizes yield gains using Phaseolus gene pool is useful to develop stress‐tolerant and high‐performing genotypes. The objective of this review is to provide breeding progress made regarding tepary bean improvement for drought adaptation. Agronomic, physiological and biochemical traits utilized for selection of drought‐tolerant genotypes are highlighted. Genetic and genomic resources developed for tepary bean or closely related species such as common bean useful for genetic analysis and breeding are discussed. Opportunities and challenges to facilitate breeding of tepary bean genotypes with improved abiotic stress adaptation are highlighted. This will enable development of drought‐tolerant tepary bean genotypes targeting selection of agronomic, physiological and biochemical traits. Use of genetically related and complementary Phaseolus species and marker‐assisted selection method is key to developing drought‐tolerant genotypes.
Stüve‐Wiedemann syndrome with multiple eruptive vellus hair cysts and clefted tongue
Authors: Lobato‐Berezo Alejandro , Tormo‐Mainar Sara , Pujol Ramon M. 
Published: January 2020

AbstractStüve‐Wiedemann syndrome is a rare autosomal recessive congenital primary skeletal dysplasia, characterized by small stature, bowed long bones, joint restrictions, hyperthermic episodes, dysautonomia, and respiratory and feeding difficulties, that usually leads to early mortality. Cutaneous manifestations have rarely been reported. We report the case of a girl with Stüve‐Wiedemann syndrome presenting with progressive development of multiple eruptive vellus hair cysts.