bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trainee Operative Autonomy in Plastic Surgery
Authors: Vargas Christina R. , Long Tobias C. , Kumar Anand R. 
Published: January 2020

Background
Appropriate, progressive trainee autonomy is critical for training competent plastic surgeons who are adequately prepared to enter independent practice. Evaluation and reporting of meaningful operative autonomy among trainees in plastic surgery are understudied.

Methods
Parallel survey instruments were developed using the Zwisch metric for progressive operative autonomy and distributed electronically to trainees and faculties in all accredited training programs. Trainees were queried about their operative autonomy in 17 core plastic surgery procedures, associated approach to logging cases, and perceived readiness to enter practice. Faculties provided assessment of their final-year trainees using the same metrics.

Results
Trainees in 28 programs and faculties in 35 programs participated. Final-year trainees reported the most operative independence with breast tissue expander reconstruction and carpal tunnel release and the least with facelift and rhinoplasty. A mean of 40% of final-year trainees reached supervision only autonomy in the procedures queried; none achieved this with rhinoplasty. Faculties identified the highest final-year trainee operative autonomy with botulinum toxin injection and burn excision and grafting; the least trainee independence was reported with rhinoplasty, cleft lip repair, and facelift. Faculty perception of final-year trainee autonomy was higher than that of trainees for 82% of procedures queried.

Conclusions
Although plastic surgery trainees endorse gradual operative autonomy overall, a majority of final-year trainees do not perceive supervision only independence in the majority of core procedures queried. Faculties perceive higher trainee operative autonomy than trainees for most procedures. Discordant approaches to case logging were identified both among trainees and between trainees and faculties. Standardization may improve both progression and assessment of operative autonomy in plastic surgery training.
A Randomized Controlled Trial Comparing Short-term Outcomes of Self-Gripping (Progrip) Mesh Versus Fibrin Sealant in Laparoscopic Total Extraperitoneal Hernioplasty
Authors: Law Tsz Ting , Ng Ka Kin , Wei Rockson , Yip Jeremy , Ng Lily , Wong Kin Yuen , Foo Chi Chung 
Published: January 2020

Background:
There are no data comparing the use of self-gripping mesh with standard mesh in total extraperitoneal repair (TEP). In this prospective study we aim to study the incidence of chronic pain between Progrip (PG) and standard mesh fixed by fibrin sealant (FS).

Materials and Methods:
Under Institutional Review Board approval, from April 2016 to May 2017, patients with primary unilateral or bilateral inguinal hernia eligible for TEP were recruited. Before mesh insertion they were randomized into PG or FS (Tisseel). Demographics, intraoperative, and postoperative data were recorded. Patients were followed up for at least 1 year. Visual Analog Scale was used to record pain scores. Primary outcome was the incidence of chronic pain at 3 months after surgery.

Results:
One hundred fifty patients were randomized. Of the 150 patients (193 hernias), 76 were randomized to PG and 74 randomized to FS. Demographic data such as age, presence of comorbidities, smoking history, mean body mass index was comparable in both groups. Bilateral hernias occurred in 25 (32.9%) and 18 (24.3%) patients in PG and FS group, respectively. Mean mesh deployment time was 283.7 seconds (range, 140 to 720 s) in PG group and 301.9 seconds (range, 67 to 1006 s) in FS group (P=0.30). A total of 5 patients were lost at follow-up and they were excluded from subsequent data analysis. Seroma occurred in 15 (20.3%) and 16 (22.5%) patients in PG and FS group, respectively (P=0.45). Mean Visual Analog Scale at 2 weeks (cough) was highest at 1.05 and 1.02 in PG and FS group, respectively (P=0.62). Eight (12.3%) and 15 (23.4%) patients in PG and FG group, respectively, reported pain at 3-month follow-up (P=0.1). Of those who experienced pain, majority was mild pain which did not affect activities of daily living. At a mean follow-up of 13.1±5.4 months, no recurrence was detected.

Conclusions:
There was no significant difference in terms of chronic pain between PG and FS group. The use of PG is effective in TEP.
Effects of Low-Dose Ketamine on the Antidepressant Efficacy and Suicidal Ideations in Patients Undergoing Electroconvulsive Therapy
Authors: Chen Qibin , Dong Jun , Luo Jie , Ren Li , Min Su , Hao Xuechao , Luo Qinghua , Chen Jianmei , Li Xiao 
Published: January 2020

Objectives
It remains controversial whether a subanesthetic dose of ketamine could modulate the antidepressant effect of electroconvulsive therapy (ECT) in patients with major depressive disorder. We investigated the effect of ketamine on accelerating the antidepressant efficacy of ECT.

Methods
One hundred twenty-seven patients with major depressive disorder were included in this randomized, placebo-controlled, double-blind study. The study group received 0.3 mg/kg ketamine, and the control group received an isovolumetric dose of normal saline before undergoing ECT under propofol anesthesia. The main outcome was the Hamilton Depression Rating Scale score after each ECT session. Suicidal ideation (SI) was also evaluated using the Hamilton Depression Rating Scale. The response, remission, and recurrence rates were analyzed using time-to-event analysis.

Results
No significant differences were found in the overall response, remission, and relapse rates between the groups (P > 0.05). The median number of ECT sessions for achieving response was 4.0 ± 0.41 in the study group and 7.0 ± 0.79 in the control group (P < 0.05). The median number of ECT sessions for achieving remission in the study and control groups was 8.0 ± 0.29 and 9.0 ± 0.48, respectively (P < 0.05). The median number of ECT sessions for achieving SI reduction in the study and control groups was 3.0 ± 0.75 and 6.0 ± 1.19, respectively (P < 0.05).

Conclusions
Low-dose ketamine (0.3 mg/kg) could modulate the antidepressant efficacy of ECT via accelerating the onset of its effects and reducing the number of ECT sessions required to obtain response, remission, and SI reduction, without influencing the relapse rates in remitting patients after ECT treatment.
GTO: a toolkit to unify pipelines in genomic and proteomic research
Authors: Almeida João R. , Pinho Armando J. , Oliveira José L. , Fajarda Olga , Pratas Diogo 
Published: January 2020

AbstractSummaryNext-generation sequencing triggered the production of a massive volume of publicly available data and the development of new specialised tools. These tools are dispersed over different frameworks, making the management and analyses of the data a challenging task. Additionally, new targeted tools are needed, given the dynamics and specificities of the field. We present GTO, a comprehensive toolkit designed to unify pipelines in genomic and proteomic research, which combines specialised tools for analysis, simulation, compression, development, visualisation, and transformation of the data. This toolkit combines novel tools with a modular architecture, being an excellent platform for experimental scientists, as well as a useful resource for teaching bioinformatics inquiry to students in life sciences.Availability and implementationGTO is implemented in C language and it is available, under the MIT license, athttp://bioinformatics.ua.pt/gto.Contactpratas@ua.ptSupplementary informationSupplementary data are available at publisher’s Web site.
Dose-Dependent Induction Of CPP Or CPA By Intra-pVTA Ethanol: Role Of Mu Opioid Receptors And Effects On NMDA Receptors
Authors: Campos-Jurado Yolanda , Martí-Prats Lucía , Morón Jose A. , Polache Ana , Granero Luis , Hipólito Lucía 
Published: January 2020

AbstractThe neurobiological mechanisms underlying alcohol motivational properties are still not fully understood, however, the mu-opioid receptors (MORs) have been evidenced as central elements in the manifestation of the alcohol reinforcing properties. Drug-associated environmental stimuli can trigger alcohol relapse and promote alcohol consumption whereby N-methyl-D-aspartate (NMDA) receptors play a pivotal role. Here we sought to demonstrate, for the first time, that ethanol induces conditioned place preference or aversion (CPP or CPA) when administered locally into the ventral tegmental area (VTA) and the associated role of MORs. We further analyzed the changes in the expression and mRNA levels of GluN1 and GluN2A subunits in designated brain areas. The expression of CPP or CPA was characterized following intra-VTA ethanol administration and we showed that either reinforcing (CPP) or aversive (CPA) properties are dependent on the dose administered (ranging here from 35 to 300 nmol). Furthermore, the critical contribution of local MORs in the acquisition of CPP was revealed by a selective antagonist, namely β-Funaltrexamine. Finally, modifications of the expression of NMDA receptor subunits in the Nucleus Accumbens (NAc) and Hippocampus after ethanol-induced CPP were analyzed at the proteomic and transcriptomic levels by western blot andIn SituHybridation RNAscope techniques, respectively. Results showed that the mRNA levels of GluN2A but not GluN1 in NAc are higher after ethanol CPP. These novel results pave the way for further characterisation of the mechanisms by which ethanol motivational properties are associated with learned environmental cues.
Titanium carbide’s effects on coatings formed on D16T aluminum alloy by plasma electrolytic oxidation
Authors: Liu Wanying , Yang Junjie , Qiu Yuhong , Liu Ying , Deng Kuanhai 
Published: January 2020

Purpose
The preferable concentration of titanium carbide was optimized and added as an additive to the micro-arc oxidation electrolyte to produce a high corrosion-resistant coating on D16T aluminum alloy.

Design/methodology/approach
Ceramic coatings were deposited on D16T aluminum alloy by plasma electrolytic oxidation in alkaline silicate electrolytes with micron titanium carbide particle suspending at different concentrations. Influences of additive concentration on morphology, elemental and phase composition and corrosion resistance of doped PEO coatings were evaluated by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD) and electrochemical methods, respectively.

Findings
Results revealed that suspending titanium carbide additives incorporated into ceramic coatings through discharging channels and chemically transformed into amorphous stage. The content of titanium in the doped coatings increased with the increasing concentration of suspending micron additive. Compared with the coating without particle addition, the corrosion resistance of the coating produced in 8 g/L titanium carbide suspension increased more than 20 times. The result indicated that the incorporation of titanium into the PEO coatings formed on the D16T aluminum alloy could effectively improve the corrosion resistance.

Originality/value
The mechanism of corporation of TiC and the mechanism of improving the corrosion resistance of the coating were proposed.
“Accelerating” and “jumping” internationalization
Authors: Weihong Chen , Xi Zhong , Lan Hailin , Zhiyuan Li 
Published: January 2020

PurposeIn recent years, the phenomena of “accelerating” and “jumping” during the international expansion of Chinese enterprises have attracted a lot of attention from scholars. However, while a CEO’s career horizon can significantly affect his or her enterprise’s strategic decision-making, few studies have explored the role of CEO career horizon in terms of “accelerating” and “jumping” internationalization.Design/methodology/approachBased on a sample of China’s A-share listed manufacturing companies from 2008 to 2017, this study explores the impact of CEO career horizon on the internationalization pace and international rhythm of enterprises.FindingsFirst, the shorter the CEO’s career horizon, the more likely the CEO can avoid risky strategic decisions, which ultimately causes a negative relationship between CEO career horizon and the internationalization pace and rhythm of the enterprise. Second, for larger and older boards of directors, there is a more negative impact of the CEO’s short-term career horizon on the internationalization pace and internationalization rhythm of the company. However, given a larger proportion of female directors and non-executive directors, the CEO’s short-term career horizon has a weaker negative impact on international pace and the rhythm of internationalization.Originality/valueFirst, based on upper echelon theory, this study interprets the influence of CEO career horizon on the time dimension of corporate internationalization (including internationalization pace and international rhythm), deepening the theory’s explanatory power. Second, by clarifying the important predictive effect of CEO career horizon on internationalization pace and international rhythm, this research enriches extant research on both variables’ antecedents, as well as that on the influence of CEO career horizon. Finally, by introducing the regulatory role of the board’s supervisory ability, this study clarifies the boundary conditions for the influence of the CEO’s career horizon on international pace and rhythm, and it expands the literature on how CEOs and boards of directors can influence corporate strategic decisions during the internationalization process.
Advanced heavy water reactor control with the aid of adaptive second-order sliding mode controller
Authors: Roy Rupam Gupta , Ghoshal Dibyendu 
Published: January 2020

Purpose
Advanced heavy water reactor (AHWR) is a pressure tube type of heavy water reactor. It eliminates high-pressure heavy water coolant resulting in a reduction of heavy water leakage losses and eliminating heavy water recovery system. It recovers the heat generated in the moderator for feed water heating. However, it requires a satisfactory technological response to develop an effective controller that attains the challenges of the very high-level safety system. Hence, they require application-specific improvement for better controlling performance.

Design/methodology/approach
The purpose of this study intends to propose a system for controlling state vectors v1 and v2and in AHWR using Grey Wolf second-order sliding mode control (GW-SoSMC) technique. The main aim of the paper is to minimize the errors between the predicted and desired azimuthal angles of the system. With this proposed method, it is possible to mitigate both the chattering phenomenon and controlling performance of AHWR system. It implements a SoSMC controller based on GWO algorithm for the purpose of controlling the state vectors in the AHWR system. It aims to accomplish a controller for improving the performance of the AHWR system.

Findings
Through the performance analysis, the efficiency of the proposed GW-SoSMC technique was verified by comparing it with various conventional algorithms, such as GW-SMC, FF-SoSMC, ABC-SoSMC, GS-SoSMC and GA-SoSMC. From the analysis, it was obtained that the implemented GW-SoSMC technique was 65.3 per cent superior to GW-SMC, 65.32 per cent superior to both FF-SoSMC and 65 per cent superior to ABC-SoSMC, 65.8 per cent superior to the GS-SoSMC and 58 per cent superior to the GA-SoSMC methods. Thus, the effectiveness of the proposed method in controlling the state vectors in AHWR was obtained.

Originality/value
This paper presents a technique for controlling the state vectors in the AHWR system using GWO algorithm. This is the first work that uses GWO-based optimization for controlling state vectors in the AHWR system.
Modeling and simulation of sheets ply separation induced by air flow
Authors: He Xin , Li XiaoPing , Yang Jinrong 
Published: January 2020

Purpose
The purpose of this paper is to investigate the mechanism of sheets ply separation induced by air flow through numerical simulation with two-way FSI (fluid-structure interaction) simulation using ANSYS and theoretical speculation.

Design/methodology/approach
The paper primarily establishes a simplified physical model of the sheets ply separation induced by air flow. Then, the force of the air flow acting on the sheet has been analyzed based on the model, and the main factor leading to separation was obtained. Furthermore, the parameter analysis was investigated based on linear stability analysis, from which the factors that affect stable separation are obtained. Finally, a series of numerical simulations are performed to verify the conclusions.

Findings
This study shows that the main separation factor is the variable air pressure in the gap between the sheets caused by the dynamic pressure air flow. Increasing the inlet velocity of the flow field will increase the separation distance but excessive velocity will lead to instability. The viscous resistance acting on the sheet and the bending stiffness of the sheet are factors that stabilize the system, and the sheet density and the restoring force can lead to instability.

Originality/value
The paper is one of the first in the literature that investigates the problem of sheets ply separation induced by air flow, which is the primary method for multi-layer separation in sheets de-stacking operations, especially for the high-speed occasion.
Analysis of the concrete shrinkage effects on the real behavior of the spatial concrete and reinforced concrete structures using the thermal analogy
Authors: Džolan Ante , Kožul Mladen , Harapin Alen , Ćubela Dragan 
Published: January 2020

Purpose
This paper aims to present an approach for the numerical simulation of concrete shrinkage. First, some physical mechanisms of shrinkage are described and then the developed numerical model for the analysis of shrinkage of spatial three-dimensional structures using thermal analogy is presented. Results of the real behavior of structures because of concrete shrinkage using the developed numerical model are compared with the experimental and it is clearly shown that the developed numerical model is an efficient tool in predicting the time-dependent behavior of all concrete structures.

Design/methodology/approach
In this paper, Fib Model Code 2010 to predict shrinkage deformation of concrete is used, and it was incorporated in the three-dimensional numerical model using the thermal analogy. Mentioned three-dimensional numerical model uses the modified Rankine material law to describe concrete behavior in tension and modified Mohr-Coulomb material law to describe concrete behavior in compression. The developed three-dimensional numerical model successfully analyzes the behavior of reinforced and/or prestressed concrete structures including time-dependent deformations of concrete as well.

Findings
Results are shown in this paper clearly demonstrate the reliability of the developed numerical model in predicting the shrinkage strain, as well as its impact on concrete and reinforced concrete structures. The results obtained using the developed numerical model are in better agreement with the experimental results, than the results obtained using the numerical models from literature that also use the Fib Model Code 2010 to predict the shrinkage strain. So, it can be concluded that for a real simulation of concrete structures, alongside the model for predicting the shrinkage strain, the models for concrete behavior in tension and compression have a very important role.

Originality/value
Results of the developed three-dimensional numerical model were compared with experimental results from literature and with theoretical foundations, and it can be talked that this numerical model presents a good tool for analysis of reinforced and prestressed concrete structures including shrinkage deformation of concrete. Results obtained using the developed three-dimensional numerical model are better agreed with experimental than results of other numerical model from literature.
Computational mechanics of the paddlefish rostrum
Authors: Riveros Guillermo A. , Acosta Felipe J. , Patel Reena R. , Hodo Wayne 
Published: January 2020

Purpose
The rostrum of a paddlefish provides hydrodynamic stability during feeding process in addition to detect the food using receptors that are randomly distributed in the rostrum. The exterior tissue of the rostrum covers the cartilage that surrounds the bones forming interlocking star shaped bones.

Design/methodology/approach
The aim of this work is to assess the mechanical behavior of four finite element models varying the type of formulation as follows: linear-reduced integration, linear-full integration, quadratic-reduced integration and quadratic-full integration. The paper also presents the load transfer mechanisms of the bone structure of the rostrum. The base material used in the study was steel with elastic–plastic behavior as a homogeneous material before applying materials properties that represents the behavior of bones, cartilages and tissues.

Findings
Conclusions are based on comparison among the four models. There is no significant difference between integration orders for similar type of elements. Quadratic-reduced integration formulation resulted in lower structural stiffness compared with linear formulation as seen by higher displacements and stresses than using linearly formulated elements. It is concluded that second-order elements with reduced integration are the alternative to analyze biological structures as they can better adapt to the complex natural contours and can model accurately stress concentrations and distributions without over stiffening their general response.

Originality/value
The use of advanced computational mechanics techniques to analyze the complex geometry and components of the paddlefish rostrum provides a viable avenue to gain fundamental understanding of the proper finite element formulation needed to successfully obtain the system behavior and hot spot locations.