bluuebunny/crossref_metadata_2025_split huggingface dataset:
Platelets and Immature Neutrophils in Preterm Infants with Feeding Intolerance
Authors: Alhamad Moath M.A. , Kumar Ambuj , Chaaban Hala , Wickline Karen M. , Ho Thao T.B. 
Published: May 2020

Objective Feeding intolerance (FI) is a common presentation of necrotizing enterocolitis (NEC) and sepsis. NEC and sepsis are associated with hematological changes, but these changes alone are not reliable biomarkers for early diagnosis. This study examined whether the combination of hematological indices and FI can be used as an early diagnostic tool for NEC or sepsis.
Study Design This retrospective cohort study included infants born at <1,500 g or <30 weeks who had symptoms of FI. The exclusion criteria were congenital or chromosomal disorders, thrombocytopenia or platelet transfusion before the onset of FI, and history of bowel resection. We compared the hematological indices from infants with pathologic FI (due to NEC or sepsis) to infants with benign FI.
Results During the study period, 211 infants developed FI; 185 met the inclusion criteria. Infants with pathologic FI (n = 90, 37 cases with NEC and 53 with sepsis) had lower birth gestational age and weight compared with 95 infants with benign FI (n = 95). Pathologic FI was associated with lower platelet count (median 152 × 103/μL vs. 285 × 103/μL, p < 0.001) and higher immature-to-total neutrophil (I/T) ratio (median 0.23 vs. 0.04, p < 0.001) at the onset of FI. Pathologic FI was also associated with a decrease in baseline platelets compared with an increase in benign FI. For diagnosis of pathologic FI, a decrease ≥10% in platelets from baseline had a sensitivity and specificity of 0.64 and 0.73, respectively, I/T ratio ≥0.1 had a sensitivity and specificity of 0.71 and 0.78, respectively, and the combination of both parameters had a sensitivity and specificity of 0.50 and 0.97, respectively.
Conclusion FI caused by NEC or sepsis was associated with a decrease in platelets from baseline, and a lower platelet level and higher I/T ratio at the onset of FI. These findings can help clinicians in the management of preterm infants with FI.
Key Points
Bevacizumab for Retinopathy of Prematurity: 2-Year Neurodevelopmental Follow-up
Authors: Zayek Michael , Parker Kaitlyn , Rydzewska Monika , Rifai Aref , Bhat Ramachandra , Eyal Fabien 
Published: May 2020

Objective This study aimed to determine whether infants who were treated with intravitreal bevacizumab (IVB) for retinopathy of prematurity (ROP) were at higher risk of death or neurodevelopmental impairment (NDI) when compared with infants who were not treated with IVB (Laser only).
Study Design This retrospective study included 146 infants born from 2009 through 2016 with a birth weight (BW) <1,000 g, gestational age <27 weeks, and required ROP therapy. Death and NDI rates were assessed at 18 to 24 months' corrected age.
Results Rates of death or severe NDI were 62 and 53% in the IVB (n = 61) and Laser only (n = 85) groups, respectively. This difference was not statistically different despite sample selection bias in treating growth-restricted infants with IVB, BW (median [IQR]) was 481 (420–583) versus 547 (473–640) g in IVB and Laser only groups, respectively, p = 0.003. The adjusted odds ratio and 95% confidence interval of death or severe NDI was 0.86 (0.33–2.20).
Conclusion Bevacizumab therapy for ROP did not affect survival and neurodevelopment of extremely preterm infants.
Key Points
Embolotherapy for Hepatic Oncology: Current Perspectives and Future Directions
Authors: Bajwa Raazi , Madoff David C. , Kishore Sirish A. 
Published: May 2020

AbstractPrimary and secondary liver cancers are a major cause of mortality worldwide. Transarterial liver-directed therapy, or embolotherapy, represents an important locoregional treatment strategy for primary and secondary liver tumors. Embolotherapeutic modalities include bland embolization (transarterial embolization), chemoembolization (transarterial chemoembolization), and radioembolization or selective internal radiotherapy. A brief technical overview of embolotherapeutic modalities as well as supportive evidence for the treatment of most common primary and secondary liver tumors will be discussed in this review. Several potential future applications, including synergy with systemic therapy, interventional theranostics, and artificial intelligence will also be reviewed briefly.
Giant Cell Tumor of Bone: 6 Years Institutional Retrospective Review
Authors: Ali Nadeem , Nabi Dar Ghulam , Shah Azad Ahmad , Kawoosa Altaf Ahmad , Mumtaz Mohammad Umar 
Published: May 2020

Abstract
Introduction Surgery is the cornerstone for the management of giant cell tumors (GCTs). There are no definite guidelines for the management. The purpose of this series was to study the patient demography and results of the surgical intervention for skeletal GCTs in our population.
Materials and Methods All the histologically diagnosed cases of GCT of bone from year 2012 to 2018 were retrospectively analyzed for patient demographics, site, and grade of the lesion, type of biopsy taken (if any), nature of surgical intervention, and final outcome with respect to complications.
Results Seventeen cases of skeletal GCT were diagnosed on histopathology. The mean age at presentation was 31.5 ± 10.9 years with females affected 1.4 times more. Proximal tibia was the most common site (29.4%) followed by distal radius and distal femur in that order. About 58.8% of the lesions were of Campanacci grade 2 and remaining were grade 3 lesions. Ten patients had extended curettage, five had en bloc resection, and one had amputation as the primary treatment. Twenty percent patients (n = 3) had local recurrence of the pathology and one patient developed distant recurrence (lung metastasis).
Conclusion Proximal tibia followed by distal radius was the most common site of GCT in our population. The tumor behavior and recurrence cannot be predicted with any grading system. The goal should be salvage of the joint by intralesional curettage, with resection reserved for distal radius GCTs, cases with extensive soft tissue extension or those with destruction of the articular cartilage and joint involvement.
Language ideological debates about linguistic landscapes
Authors: Vessey Rachelle , Sheyholislami Jaffer 
Published: May 2020

AbstractIn 2013, Richmond city council was presented with a petition calling for the regulation of all language signs, drawing national attention to the amount of Chinese-only signage. The signage debate has become well-known in Canada as a result of the media, which has provided a platform for debate through online reader commentary. By applying concepts from linguistic landscapes, language ideologies and nationalism in addition to analytical tools from SFL, we employ critical discourse studies to examine how representations of and responses to language signage in online news commentary contribute to the construction of in-groups and out-groups in the Canadian context. Findings show that stereotypical representations of ethnicity and culture are represented as a threat to the Canadian status quo. Also, contradictory ideologies of Canadian official bilingualism are employed to justify discrimination against Chinese language speakers. Findings suggest that language ideologies remain deeply tied to understandings of Canadian nationhood and belonging.
Learning the properties of Buton asphalt as an oil shale in Buton island to expand the knowledge of students about physics
Authors: Zainuddin E S , Hendrajaya L 
Published: May 2020

Abstract
Asphalt in Buton Island, Southeast Sulawesi, Indonesia, has a large reserve amount of around 650 million tons. In Buton, asphalt is only used for road construction, but this asphalt has characteristics that can be utilized as a substance to produce crude oil. The purposes of this research are to increase or expand the knowledge of educated participants about the characteristics and advantages of Buton asphalt and oil shale as community natural resources and to compare the density of each asphalt mining area namely Kabungka (winto mine), Lawele, and Sampolawa. It aims is to make Buton asphalt as a source of learning. The research method used is the literature study and experiment. The results of the study are that the characteristics of asphalt Buton approach the characteristics of oil shale in Green River, US. The density of Buton asphalt in each region is different. Conclusion of the research that asphalt/tar sand on Buton Island is categorized as a solid/semi-solid type hydrocarbon oil shale. The implementation of this study can be used for senior high school of class X student by visiting the asphalt mine to conduct simple experiments such as measuring the height of the asphalt cliff and determining the direction of the wind eye. Asphalt is used to measure its density. The experiment procedure is made in a module that will later be used by students.
Construction and testing of decision-problem solving skills test instruments related basic physics content
Authors: Yusal Y , Suhandi A , Setiawan W , Kaniawati I 
Published: May 2020

Abstract
The aim of this study is to produce test instrument items decision-problem solving skills related to the content of Heat Transfer. The construction of the test instrument has been done using scaffolding which includes stages: description of indicator of decision-problem solving skills, operationalization of indicators, construction of items scenarios, writing of test items, validation of test items, and test of reliability. Validation of test items has been done by five experts namely three education evaluation experts and two physics experts. Test of reliability was carried out by involving 35 students of physics education program at one of the universities in South Sulawesi province. The construction process of the test instrument produced two items of test decision problem solving skills related to the concept of conduction and heat radiation. The results of expert validation of the decision-problem solving test items stated that the constructed items had high validity, and the results of the test reliability showed that the constructed test instruments had a high degree of consistency permanence. These results indicate that the product of decision-problem solving test instrument is worthy of being used for measuring decision-problem solving skills for students of Physics education programs who contract Basic Physics courses.
Improving the mental model of high school students related to the concept of global warming through the implementation of the context based learning (CBL) model combined with the CM2RA strategy
Authors: Ulum A S , Basori H , Suhandi A , Samsudin A 
Published: May 2020

Abstract
The aim of this study was to improve the mental model of high school students related to the concept of global warming through the application of the CBL model using the CM2RA strategy (context, microscopic models, macroscopic phenomena, and analogy representation). The mental model categories reviewed include scientific, synthetic and initial mental models. This mental model category is determined based on the test results data level of conceptual understanding. A pre-experiment method with one group pretest-posttest design was used in this research. The number of research subjects was 40 students consisting of 24 female students and 16 male students, in one of the high schools in the Tasikmalaya district of West Java province. The instrument used to collect data is a test of understanding the concept of global warming in the form of essays covering three parts of the question. The results showed that before the application of CBL, the number of students in each mental model category was: scientific mental model (5%), synthetic (40%), and initial (55%), whereas after the application of CBL, the number of students in each category of mental models becomes: scientific mental model (78%), synthetic (15%), and initial (7%). These results indicate that the implementation of CBL with CM2RA strategies has high effectiveness in facilitating the achievement of the scientific mental model.
PhET simulation software-based learning to improve science process skills
Authors: Haryadi R , Pujiastuti H 
Published: May 2020

Abstract
The purpose of this study is to find out the results of the application of media PhET Simulation in physics learning in matter of temperature and heat. The research design used was a randomized design control group pre-test post-test. The study population was all 11th grade students of SMA Y Serang which numbered five classes. The research sample consisted of one experimental class and one control class. The results showed that the application of physics learning using media PhET simulation on temperature and heat material produced a 37% higher N-gain value than the control class using direct learning. It can be concluded that PhET simulation software-based learning is interactive learning in physics learning and can improve students’ science process skills.
The exploration of character education contents in the physics textbooks about newton’s law
Authors: Dewi T S , Suresman E , Ramalis T R 
Published: May 2020

Abstract
Character education is recommended to be integrated into all school subjects as an effort to solve the problem of moral degradation among the Indonesian students. Therefore, this study aims to explore the character education contents in the physics textbooks used by the teachers in the learning process. The findings demonstrated that there were 14 character values contained in the textbooks, which have had recommendations from the Ministry of National Education of Indonesia as the feasible learning sources.
Pre-service teacher’s physics attitude towards physics laboratory in Aceh
Authors: Saputra H , Suhandi A , Setiawan A , Permanasari A 
Published: May 2020

Abstract
This research aims to find out the pre-service teacher’s physics attitude towards physics laboratory in one of the Universities in Aceh. The research method uses a quantitative descriptive approach. Data collection techniques used a scale questionnaire that was adapted from several previous researchers. The Subject of this study is 45 physics student prospective students who were taken from the semester, II, IV, and IV as subjects of the study. The data analysis technique is done by calculating the mean of each aspect and indicator and the independent t-test to see differences in attitudes based on gender. Overall, the results of the study showed a negative attitude towards physical practicum activities with the acquisition of a mean of 2.78. The statistical test results for normally distributed and homogeneous data show no significant differences (df. 43, sig. 0.90> 0.04) between the attitudes of male and female students. Negative attitudes towards physics laboratory are caused by the design of practicum verification that does not provide benefits to improve understanding, practice scientific inquiry skills, thinking skills, and solving physics problems. Efforts to improve attitudes toward physics practicum can be done through the design of practical activities oriented to humanistic psychology and constructivism by involving students actively investigating.
The role of science project based peer interaction on improving collaborative skills and physical problem solving: a mini review
Authors: Setyowidodo I , Jatmiko B , Susantini E , Handayani A D , Pramesti Y S 
Published: May 2020

Abstract
Problem solving and collaborative skills are part of the 21st century skills that students need to have. So it is necessary to develop a model of learning that can enhance those abilities. The methods of this study is literatur review. The literature about Problem Based Learning and the weakness of Problem Based Learning are discussed to find the Science Project Based Peer Interaction (SPBPI). This research technique uses a literature analysis. This study aims at efforts to improve student’s collaborative skills and problem solving through the learning of Science Project Based Peer Interaction (SPBPI). The results of this study will later be implemented in learning to improve collaborative skills and student problem solving through learning ScienceProject-Based Peer Interaction (SPBPI). By the implementation of this Science Project ScienceProject-Based Peer Interaction (SPBPI), student’s collaborative skill and problem soling ability will enhance.
Practicality of physics module based on contextual learning accompanied by multiple representations in physics learning on senior high school
Authors: Mahardika I K , Delftana R E , Rasagama I G , Suprianto  , Rasyid A N , Sugiartana I W 
Published: May 2020

Abstract
The purpose of this research was to describe the practicality of a physics module based on contextual learning accompanied by multiple representations. Practicality of this module could be determined from observation of learning implementation using this module and student’s response after using this module. This research used development model of 4-D (define, design, develop, and disseminate). Practicality was determined to develop a step and disseminate steps. However, practicality could be determined after the module was valid. Based on the results of logic validity and empiric validity data analysis, the module could be said to be very valid with a percentage of 86.88% and 89.96% respectively. Limited trial and class trial in develop step was done in SMA Nuris Jember and disseminate trial was done in MA Nuris Jember. Based on observation of learning implementation using this module, it could be known that this module was very practical with an average percentage of 80.46%. Based on student’s responses after using the module, it could be known that this module was very practical with an average percentage of 95.22%. Therefore, the physics module based on contextual learning that accompanied by multiple representations was very practical to use in physics learning on senior high school.
Effectiveness of edmodo to improve senior high school students’ creative thinking skills in momentum and impulse topics
Authors: Hadjarati Y A , Arota A S , Mursalin  , Odja A H 
Published: May 2020

Abstract
The study was aimed to investigate the effectiveness of e-learning-based innovative learning set employing Edmodo to improve the senior high school student’s creative thinking in momentum and impulse learning material. It applied an experimental method with one group pretest-posttest design. The study was conducted in Integrated Senior High School Wira Bhakti Gorontalo by having 20 students of the class of X IPA 2 as respondents. It was a research and development type using research stages by Jerold F. Kemp consisting of determining general instructional goal, analyzing student’s characteristics, determining specific instructional goals, determining learning materials, determining the pre-test, determining teaching and learning strategies, media, and sources, coordinating the supporting facilities, and evaluating (post-test). The developed learning set was syllabus, lesson plan, learning material, student’s worksheet, and test of creative thinking ability as well as an appropriate assessment instrument. Data analysis result revealed that there was an improvement of student’s creative thinking ability proved by the average value of N-Gain for 0,70 in the high category. Based on the data analysis, it can be concluded that an e-learning-based innovative learning set employing Edmodo was effective to improve the senior high school student’s creative thinking in momentum and impulse learning material.
Effectiveness of student worksheets on environmental project-based e-learning model in building student character
Authors: Sarah I , Rani S 
Published: May 2020

Abstract
Education world through learning in the classroom has a huge influence in building the values of student characters. Mathematics as a subject is given at all levels of education and has more time allocated each week than other subject has the opportunity to build student character value. This study aims to develop mathematics student worksheets and their effectiveness in the context of student character. This type of research is research with design and development. This research consists of three stages, namely Self Evaluation, Prototyping, and Field Test. The initial step of the research is to use various sources in the field and literature review. Product design is done by preparing student worksheets and student character observation sheets. Products that have been designed are then developed by means of judgment, trials and revisions. From the results of the development then a student worksheets hypothetical product is obtained and will be tested for its effectiveness. Effectiveness testing is carried out in the use of trial activities through the implementation of student worksheets hypothetical product. The results showed that the hypothetical student worksheets was effective in establishing honest, maos, mamaos, tanginas, someah, sauyunan, and discipline characters.
Attitude towards statistics among pre-service teachers of institute of teacher education
Authors: Mustam A A , Adnan M , Johnny J , Setambah M A B 
Published: May 2020

AbstractStatistics is increasingly being recognized as a necessary component in many colleges, universities and teacher training programs. The importance of this component of mathematics is essential to bettering one’s economic prospects, gaining employment, keeping employment, and obtaining better employment. The main objective of this study was to determine the attitude of pre-service teachers towards statistics. This study also aimed to investigate the relationship between attitude towards statistics with gender, major and campus respectively. The participants comprised of 80 undergraduates from the Institute of Teacher Education (IPG) who were enrolled in the preparatory programme for the bachelor’s degree in education; whereby, they need to undertake the Basic Statistics Course. They consisted of 3 main majors, namely, Malay Language; Physical Education and Health; and Design and Technology from two campuses which are Bahasa Melayu Campus and Temenggong Ibrahim Campus. The Survey of Attitudes toward Statistics (SATS 36) which was translated into Malay language and contains 36 items that assess six constructs (r=.827) was used to answer the main objective of this study. The study found that the attitude of pre-service teachers towards statistics were ranked medium (3.437).
Students mathematical communication ability in geometry
Authors: Pangaribuan T R , Martadiputra B A P , Usdiyana D , Sihotang R O 
Published: May 2020

Abstract
The aim of this study is to describe the communication ability of grade 8 students in Euclidean solid space topics based on Prior Mathematical Ability (PMA). The subject of this study consisted of 30 students. This research approach was quantitative with a descriptive method. Data collected by the test which developed based on indicators of mathematical communication. The indicators of mathematical communication used in this study are: (1) expressing a mathematical idea to the form of image; (2) expressing real objects or image to the form of mathematics; (3) state daily events in a language or mathematical symbol; (4) explain ideas, situations, and pictures in writing to mathematical form. The results showed that the average percentage of communication ability of all students was 47.68%. While the average percentage of students achieving in a high category was 62.5%. That was above the overall average of students. The average percentage of student achievement in a moderate category was 45.54%, and the percentage of students achievement in a low category was 45.00%.