bluuebunny/crossref_metadata_2025_split huggingface dataset:
Luminescence and Radiocarbon Dating of Mortars at Milano-Bicocca Laboratories
Authors: Panzeri Laura , Maspero Francesco , Galli Anna , Sibilia Emanuela , Martini Marco 
Published: February 2020

ABSTRACTThis work shows the results of optically stimulated luminescence (OSL) and radiocarbon (14C) dating applied to mortars of historical structures in northern Italy. All the results are compared with archaeological evidence and thermoluminescence (TL) dating of bricks. The main issue for OSL mortar dating is that the quartz grains contained in the mortar may be only partially bleached, leading to an overestimation of the sample age. In order to identify the best protocol to apply, both multi-grain (MG) and single grain (SG) methods were used. The minimum age model (MAM) statistical approach was applied to refine their accuracy. However, the identification of the bleached grains is not always successful, indicating that further investigations are needed to develop suitable dating protocol. For the 14C technique, a crucial aspect is the selection of anthropogenic calcite. In this work the mortars were treated using a Cryosonic method to select anthropogenic calcite from raw material, and the obtained powder was sieved to select the finer fraction. Unfortunately, only in two cases an acceptable amount of sample could be obtained. All the fractions were dated via accelerator mass spectrometry (AMS), and the results compared with independently obtained dates. The results show that the execution of the dating analysis requires previous characterizations to assess the nature of the mortar components and avoid unusable fractions.
Aragonite Fraction Dating of Vermetids in the Context of Paleo Sea-Level Curves Reconstruction
Authors: Moreira Vinicius N , Macario Kita D , Guimarães Renato B , Dias Fábio F , Araujo Julia C , Jesus Perla , Douka Katerina 
Published: February 2020

ABSTRACTIdentifying and tackling recrystallization is a critical factor in the reliable radiocarbon (14C) dating of carbonates, since exogenous carbon can be incorporated and thus mask the real age of the samples. Vermetids are among the most important bioindicators used for paleo sea-level reconstruction, and the accuracy of their chronology can significantly impact sea-level curves. Age differences larger than 1 14C kyr before and after acid etching, combined with X-ray diffraction (XRD) analysis that indicates a significant amount of calcite still remains in the shell, led us to apply the previously developed carbonate density separation protocol (CarDS). Using a solution of sodium polytungstate, with density of 2.80 g/cm3, we successfully separated different carbonate fractions for a set of 10 vermetid samples from the coast of Rio de Janeiro, southeast of Brazil. Each separation was verified by XRD analysis and the 14C concentrations of different fractions were compared. The results show that the calcite fraction in the studied vermetid samples varied from 12 to 63% and aragonite fraction ages are up to 2 14C kyr older than the raw samples, thus confirming the efficacy of CarDS in removing young carbonates and the importance of density separation to vermetids prior to accelerator mass spectrometry (AMS) dating.
Fed by Famine: The Hindu Mahasabha's politics of religion, caste, and relief in response to the Great Bengal Famine, 1943–1944
Authors: SARKAR ABHIJIT 
Published: February 2020

AbstractThis article demonstrates how the Great Bengal Famine of 1943–1944 and relief activism during it fed the politics of the Hindu right, a development that has not previously received much scholarly attention. Using hitherto unused primary sources, the article introduces a novel site to the study of communal politics, namely, the propagation of Hindu communalism through food distribution during a humanitarian crisis. It examines the caste and class bias in private relief and provides the first in-depth study of the multifaceted process whereby the Hindu Mahasabha used the famine for political purposes. The party portrayed Muslim food officials as ‘saboteurs’ in the food administration, alleged that the Muslim League government was ‘creating’ a new group of Muslim grain traders undermining the established Hindu traders, and publicized the government's failure to avert the famine to prove the economic ‘unviability’ of creating Pakistan. This article also explores counter-narratives, for example, that Hindu political leaders were deliberately impeding the food supply in the hope that starvation would compel Bengali Muslims to surrender their demand for Pakistan. The politics of religious conversion played out blatantly in famine-relief when the Mahasabha accused Muslim volunteers of converting starving Hindus to Islam in exchange for food, and demanded that Hindu and Muslim famine orphans should remain in Hindu and Muslim orphanages respectively. Finally, by dwelling on beef consumption by the army at the time of an acute shortage of dairy milk during the famine, the Mahasabha fanned communal tensions surrounding the orthodox Hindu taboo on cow slaughter.
Can Emergency Medical Services (EMS) Shorten the Time to Stroke Team Activation, Computed Tomography (CT), and the Time to Receiving Antithrombotic Therapy? A Prospective Cohort Study
Authors: Alabdali Abdullah , Yousif Sami , Alsaleem Abdullah , Aldhubayb Mazen , Aljerian Nawfal 
Published: February 2020

AbstractIntroduction:Stroke is a major emergency that can cause a significant morbidity and mortality. Advancement in stroke management in recent years has allowed more patients to be diagnosed and treated by stroke teams; however, stroke is a time-sensitive emergency that requires a high level of coordination, particularly within the prehospital phase. This research is to determine whether patients received by Emergency Medical Services (EMS) at a tertiary health care facility had shorter stroke team activation, time to computed tomography (CT), or time to receive intravenous thrombolytics.Methods:This research is a prospective cohort study of adults with stroke symptoms who required stroke team activation at a tertiary medical facility. The study included all patients received from September 1, 2017 through August 31, 2018. The primary outcome was the time difference to stroke team activation between patients received by EMS compared to patients that arrived by a private method of transportation. The secondary outcomes were the difference in time to CT scan and the time to receive intravenous recombinant tissue plasminogen activator (rtPA).Results:There were 75 (34.1%) patients who had been received by EMS, while 145 (65.9%) patients arrived via private transportation method (private car or by a friend/family member). The mean time to stroke team activation, time to CT, and time to receive thrombolytic therapy for the EMS group were: 8.19 (95% CI, 6.97 - 9.41) minutes; 18 (95% CI, 15.9 - 20.1) minutes; and 13.1 (95% CI, 6.95 - 19.3) minutes, respectively. Those for the private car group, on the other hand, were: 16 (95% CI, 12.4 - 19.6) minutes; 23.39 (95% CI, 19.6 - 27.2) minutes; and nine (95% CI, 4.54 -13.5) minutes, respectively. There was a significantly shorter time to stroke team activation for patients arriving via EMS compared to private car (P ≤ .00), but no significant difference was found on time to CT (P = .259) or time to receive rtPA (P = .100).Conclusion:Emergency Medical Service transportation of stroke patients can significantly shorten the time to stroke team activation, leading to shorter triage and accelerated patient management. However, there was no statistical difference in time to CT or time to receive rtPA. Patients with stroke symptoms may benefit more from EMS transportation compared to private methods of transportation.
Study of Medical Demand-Supply Balance for the Nankai Trough Earthquake
Authors: Takada Yosuke , Otomo Yasuhiro 
Published: February 2020

AbstractIntroduction:The Nankai Trough, which marks the boundary between the Eurasian and Philippine Sea plates, is forecasted to create a catastrophic earthquake and tsunami within 30 years. The Japanese government believes that the number of casualties would be huge. However, the exact number of severely injured (SI) people who would need emergency and intensive care has not been identified.Objective:This study, therefore, aimed to clarify the gap between medical supplies and forecasted demand.Methods:The official data estimating the number of injured people were collected, together with the number of intensive care unit (ICU) and high care unit (HCU) beds from each prefecture throughout Japan. The number of SI cases was recalculated based on official data. The number of hospital beds was then compared with the number of SI people.Results:The total number of hospitals in Japan is 8,493 with 893,970 beds, including 6,556 ICU and 5,248 HCU beds. When the Nankai Trough earthquake occurs, 187 of the 723 disaster base hospitals (DBHs) would be located in the areas with a seismic intensity of an upper six on the Japanese Seismic Intensity Scale (JSIS) of seven, and 79 DBHs would be located in the tsunami inundation area. The estimated total number of injured people would be 661,604, including 26,857 severe, 290,065 moderate, and 344,682 minor cases.Conclusion:Even if all ICU and HCU beds were available for severe patients, an additional 15,053 beds would be needed. If 80% of beds were used in non-disaster times, the available ICU and HCU beds would be only 2,361. The Cabinet Office of Japan (Chiyoda City, Tokyo, Japan) assumes that 60% of hospital beds would be unavailable in an area with an upper six on the JSIS. The number of ICU and HCU beds that would be usable during a disaster would thus further decrease. The beds needed for severe patients, therefore, would be significantly lacking when the Nankai Trough earthquake occurs. It would be necessary to start the treatment of those severe patients who are “more likely to be saved.”
The Sun Herald Sydney City-2-Surf Fun Run – Historical Injury Patterns and Factors Influencing Injury Type and Frequency
Authors: Vassil John C. , Winn Linda , Heslop David J. 
Published: February 2020

AbstractIntroduction:The Sydney City-2-Surf (Australia) fun run is the world’s largest annual run entered by around 80,000 people. First aid planning at mass-participation running events such as the City-2-Surf is an area in the medical literature that has received little attention. Consequently, first aid planning for these events is based on experience rather than evidence. The models for predicting casualties that currently exist in the literature are either dated or not statistically significant.Aim:The aim of this study was to characterize patterns of injuries linked to geographic location across the course of the City-2-Surf, and to explore relationships of injury types with location and meteorological conditions.Methods:Records for formally treated casualties and meteorological conditions were obtained for the race years 2010-2016 and statistically analyzed to find associations between meteorological conditions, geographic conditions, casualty types, and location.Results:The most common casualties encountered were heat exhaustion or hyperthermia (39.2%), musculoskeletal (25.4%), and physical exhaustion (10.2%). Associations were found between gradient and the location. Type of casualty incidence with the individual distribution trends of casualty types were quite clear. Clusters of musculoskeletal casualties emerged in the parts of the course with the steepest negative gradients, while a cluster of cardiovascular events was found to occur at the top of the “heartbreak hill,” the longest climb of the race. Regression analysis highlighted the linear relationship between the number of heat and physical exhaustion casualties and the apparent temperature (AT) at 12:00pm (R2 = 0.59; P = .044). This linear equation was used to formulate a model to predict these casualties.Conclusion:The findings of this study demonstrate the relationship between meteorological conditions, geographic conditions, and casualties. This will assist planners of other similar events to determine optimum allocation of resources to anticipated injury and illness burden.
In-transit cold treatment: a case of institutional path dependence
Authors: Lubello Pasquale , Codron Jean-Marie 
Published: February 2020

AbstractIn-transit cold treatment consists of exposing food commodities – generally fresh agricultural products – to temperatures approaching 0 °C for a variable number of days during shipping in purpose-equipped containers in order to manage the risks of quarantine contamination. In this paper, we show that in-transit cold treatment is frequently required in the international trade of apples potentially affected by Mediterranean fruit fly (Ceratitis Capitata), despite the existence of potentially less costly and equally effective alternative means of applying the same treatment, in particular ‘cold storage’. We then try to understand why these alternative methods do not emerge spontaneously or become more widespread. We suggest that technical aspects and their respective costs are not always the most important factors. Transaction costs may also come into play. In accordance with ‘institutional path dependence’ literature, we suggest that the negotiation costs a country has to bear in order to encourage its trading partners to adopt an alternative treatment are high enough for it to be preferable to continue using the current solution, despite its higher adoption cost.
Confirmation and characterization of cyhalofop-butyl–resistant Chinese sprangletop (Leptochloa chinensis) populations from China
Authors: Peng Yajun , Pan Lang , Liu Ducai , Cheng Xiaomei , Ma Guolan , Li Sifu , Liu Xueyuan , Wang Lifeng , Bai Lianyang 
Published: February 2020

AbstractChinese sprangletop [Leptochloa chinensis (L.) Nees] is one grass weed severely affecting rice (Oryza sativa L.) growth in paddies in China. Cyhalofop-butyl is the main herbicide used to control grass weeds in Chinese paddy fields, especially for controlling L. chinensis; however, L. chinensis has evolved resistance to cyhalofop-butyl due to continuous and extensive application. To investigate cyhalofop-butyl resistance levels and mechanisms in L. chinensis in some of the Chinese rice areas, 66 field populations were collected and treated with cyhalofop-butyl. Of these tested populations, 10 showed a high level of resistance to cyhalofop-butyl; the 50% effective dose ranged within 108.4 to 1,443.5 g ai ha−1 with resistance index values of 9.1 to 121.8 when compared with the susceptible population. Acetyl-coenzyme A carboxylase genes (ACCase) of susceptible and all 10 resistant populations were amplified and sequenced. Among them, Ile-1781-Leu, Trp-2027-Cys, Trp-2027-Ser, and Ile-2041-Asn mutations were found in five resistant populations. No known resistance-related mutations were found in the other five resistant populations, indicating that resistance to cyhalofop-butyl in these populations was likely to be endowed by non–target site resistance mechanisms. Notably, the Ile-1781-Leu and Trp-2027-Cys substitutions have previously been reported, but this is the first report of Trp-2027-Ser and Ile-2041-Asn mutations in L. chinensis. Furthermore, three derived cleaved amplified polymorphic sequence methods were developed to rapidly detect these mutations in L. chinensis.
Pore‐Scale Investigation Of Methane Hydrate‐Bearing Sediments Under Triaxial Condition
Authors: Lei Liang , Seol Yongkoo 
Published: February 2020

AbstractMechanical behavior of hydrate‐bearing sediments is critical for well stability, reservoir deformation, and sea floor settlement during gas production. Current understanding on the mechanism of hydrate strengthening hosting sediments relies on conceptual models based on idealistic pore‐scale assumptions. Yet pore‐scale study is rare and limited to hydrate‐bearing sediments formed with surrogate guest molecules rather than methane. We present for the first time pore‐scale triaxial test results of methane hydrate‐bearing sediments. Besides the traditional stress‐strain relationship, we further explored (1) sand particle crushing and (2) pressure‐temperature dependent strength variations and (3) creep of hydrate‐bearing sediments. Results show that as hydrate enables the sand skeleton to bear additional loads, the potential of sand crushing upon hydrate dissociation also increases. Strength of hydrate‐bearing sediments decreases as pressure‐temperature condition approaches hydrate phase boundary. Hydrate‐bearing sediments creep and heal with time. The new observations suggest additional complications to be considered during gas production.
Retrievals of Convective Detrainment Heights Using Ground‐Based Radar Observations
Authors: Starzec M. , Mullendore G. L. , Homeyer C. R. 
Published: February 2020

AbstractTo better constrain model simulations, more observations of convective detrainment heights are needed. For the first time, ground‐based S band radar observations are utilized to create a comprehensive view of irreversible convective transport over a 7‐year period for the months of May and July across the United States. The radar observations are coupled with a volumetric radar echo classification scheme and a methodology that uses the convective anvil as proxy for convective detrainment to determine the level of maximum detrainment (LMD) for deep moist convection. The LMD height retrievals are subset by month (i.e., May and July), by morphology (i.e., mesoscale convective system, MCS, and quasi‐isolated strong convection, QISC), and region (i.e., northcentral, southcentral, northeast, and southeast). Overall, 135,890 deep convective storms were successfully sampled and had a mean LMD height of 8.6 km or tropopause‐relative mean LMD height of
4.3 km; however, LMD heights were found to extend up to 2 km above the tropopause. May storms had higher mean tropopause‐relative LMD heights, but July storms contained the highest overall LMD heights that more commonly extended above the tropopause. QISC had higher mean tropopause‐relative LMD heights and more commonly had LMD heights above the tropopause while only a few MCSs had LMD heights above the tropopause. The regional analysis showed that northern regions have higher mean LMD heights due to large amounts of diurnally driven convection being sampled in the southern regions. By using the anvil top, the highest possible convective detrainment heights extended up to 6 km above the tropopause.
GEOS‐S2S Version 2: The GMAO High‐Resolution Coupled Model and Assimilation System for Seasonal Prediction
Authors: Molod Andrea , Hackert Eric , Vikhliaev Yury , Zhao Bin , Barahona Donifan , Vernieres Guillaume , Borovikov Anna , Kovach Robin M. , Marshak Jelena , Schubert Siegfried , Li Zhao , Lim Young‐Kwon , Andrews Lauren C. , Cullather Richard , Koster Randal , Achuthavarier Deepthi , Carton James , Coy Lawrence , Friere Julliana L. M. , Longo Karla M. , Nakada Kazumi , Pawson Steven 
Published: February 2020

AbstractThe Global Modeling and Assimilation Office (GMAO) has recently released a new version of the Goddard Earth Observing System (GEOS) Subseasonal to Seasonal prediction (S2S) system, GEOS‐S2S‐2, that represents a substantial improvement in performance and infrastructure over the previous system. The system is described here in detail, and results are presented from forecasts, climate equillibrium simulations, and data assimilation experiments. The climate or equillibrium state of the atmosphere and ocean showed a substantial reduction in bias relative to GEOS‐S2S‐1. The GEOS‐S2S‐2 coupled reanalysis also showed substantial improvements, attributed to the assimilation of along‐track absolute dynamic topography. The forecast skill on subseasonal scales showed a much improved prediction of the Madden‐Julian Oscillation in GEOS‐S2S‐2, and on a seasonal scale the tropical Pacific forecasts show substantial improvement in the east and comparable skill to GEOS‐S2S‐1 in the central Pacific. GEOS‐S2S‐2 anomaly correlations of both land surface temperature and precipitation were comparable to GEOS‐S2S‐1 and showed substantially reduced root‐mean‐square error of surface temperature. The remaining issues described here are being addressed in the development of GEOS‐S2S Version 3, and with that system GMAO will continue its tradition of maintaining a state‐of‐the‐art seasonal prediction system for use in evaluating the impact on seasonal and decadal forecasts of assimilating newly available satellite observations, as well as evaluating additional sources of predictability in the Earth system through the expanded coupling of the Earth system model and assimilation components.
ROS in cancer therapy: the bright side of the moon
Authors: Perillo Bruno , Di Donato Marzia , Pezone Antonio , Di Zazzo Erika , Giovannelli Pia , Galasso Giovanni , Castoria Gabriella , Migliaccio Antimo 
Published: February 2020

AbstractReactive oxygen species (ROS) constitute a group of highly reactive molecules that have evolved as regulators of important signaling pathways. It is now well accepted that moderate levels of ROS are required for several cellular functions, including gene expression. The production of ROS is elevated in tumor cells as a consequence of increased metabolic rate, gene mutation and relative hypoxia, and excess ROS are quenched by increased antioxidant enzymatic and nonenzymatic pathways in the same cells. Moderate increases of ROS contribute to several pathologic conditions, among which are tumor promotion and progression, as they are involved in different signaling pathways and induce DNA mutation. However, ROS are also able to trigger programmed cell death (PCD). Our review will emphasize the molecular mechanisms useful for the development of therapeutic strategies that are based on modulating ROS levels to treat cancer. Specifically, we will report on the growing data that highlight the role of ROS generated by different metabolic pathways as Trojan horses to eliminate cancer cells.