bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiological and pathological characteristics of Cutaneous Leishmaniasis from Baluchistan Province of Pakistan
Authors: Khan Aisha , Sajid Rawan , Gul Shaista , Hussain Ashiq , Zehri Mohammad Tahir , Naz Shumaila , Simsek Sami , Waseem Shahid , Afzal Muhammad Sohail , Naqvi Syed Kamran Ul Hassan , Qasim Muhammad , Ahmed Haroon 
Published: December 2020

AbstractCutaneous Leishmaniasis (CL) is considered a neglected tropical disease which in Pakistan can now be considered as a growing public health problem. The exact figures on the magnitude of the disease are lacking both at the national and regional level and only a few health centres are available for diagnosis of CL. The present study was designed to identify the epidemiology of CL infection from August 2018 to December 2019 and to assess clinical aspects of CL in Baluchistan Province of Pakistan. A total of 4072 clinically suspected CL cases were analysed statistically. The highest number of CL cases were reported in May, followed by April, January and then July, February and June and the lowest number of cases were observed in March and November. The highest prevalence rate was found in males where 38% of reported cases were aged 0–9 years. The majority (24.4%) of lesions were found on the hands followed by the face in which cheeks, ears and nose were the effected organs. About 50% of the participants have single lesion while 14% of the participants had two and nearly 3% of the participants have six lesions. The atypical clinical presentations were observed in Baluchistan and common unusual presentations were lupus erythematosus. The study findings suggest that more epidemiological studies and health education campaigns are needed for the population awareness regarding CL in Baluchistan. It is recommended that risk factors should be evaluated to establish control and management strategies to prevent disease at the individual and community level.
Intergovernmental Organizations and the Possibility of Institutional Learning: Self-Reflection and Internal Reform in the Wake of Moral Failure
Authors: Erskine Toni 
Published: December 2020

AbstractOne type of change that has lurked at the edges of scholarly discussions of international politics—often assumed, invoked, and alluded to, but rarely interrogated—islearning. Learning entails a very particular type of change. It is deliberate, internal, transformative, and peaceful (in the sense of being uncoerced). In this contribution to the roundtable “International Institutions and Peaceful Change,” I ask whether intergovernmental organizations (IGOs) can learn in a way that is comparable to the paradigmatic learning of individual human beings. In addressing this question, I take three steps. First, I explore references to corporate entities “learning” within the discipline of international relations (IR) and ask whether what is being proposed is, in fact, genuine learning by the organizations themselves. Second, I attempt to construct a robust account of institutional learning that departs from these conceptions and acknowledges instead the self-reflection and structural transformation that I argue learning at the corporate level requires. Third, for the purpose of illustration, I turn briefly to the UN following the 1994 genocide in Rwanda and the slaughter of more than eight thousand men and boys outside Srebrenica in 1995 to identify examples of each stage of institutional learning. Finally, I offer three provisional claims about my proposed conception of institutional learning that warrant attention in future work. Namely, I suggest that institutional learning: (1) cannot be equated with moral progress; (2) is possible despite formal organizations being incapable of emotional responses such as shame or regret; and, perhaps most controversially, (3) can occur at the level of the IGOwithoutprior or parallel learning taking place at the level of the state or individual human actor.
COMPENSATION AND CONTINUITY
Authors: Steel Sandy 
Published: December 2020

ABSTRACTThis article examines accounts of the moral basis of compensatory duties that explain such duties as the continuation, in some way, of the pre-wrong normative situation. I identify, contrast, and assess three versions of this view—duty continuity, right continuity, and reasons continuity. I argue that each version is defensible, once properly articulated. The article responds to a range of objections to these views that have not received much critical attention by their proponents.
Fruit and vegetable consumption among older adults: influence of urban food environment in a medium-sized Brazilian city
Authors: Almeida Luciene Fátima Fernandes , Novaes Taiane Gonçalves , Pessoa Milene Cristine , do Carmo Ariene Silva , Mendes Larissa Loures , Ribeiro Andréia Queiroz 
Published: December 2020

AbstractObjective:To examine the association between urban food environment and regular consumption of fruits and vegetables (FV) by older adults from a medium-sized Brazilian city.Design:Cross-sectional study based on data related to (1) objective assessment of establishments with predominant sale of unprocessed/minimally processed foods, mixed establishments and establishments with predominant sale of ultra-processed foods; (2) regular consumption of FV (≥ 5 times/week), health and socio-demographic variables of community-dwelling older adults. Tertiles of proximity between food establishments and older adults’ residence were calculated. Poisson generalised estimating equations with robust variance, adjusted for individual and contextual variables, were used to estimate the independent association between the proximity of establishments and regular consumption of FV.Setting:Medium-sized Brazilian city.Subjects:Representative sample of community-dwelling older adults (n 549).Results:Older adults travelled the longest distances to establishments with predominant sale of unprocessed/minimally processed foods. The longer the distance to establishments with predominant sale of unprocessed/minimally processed foods, the lower the prevalence of regular consumption of FV (tertile 2: prevalence ratio (PR) = 0·86; 95 % CI = 0·74, 0·99; tertile 3: PR = 0·84; 95 % CI = 0·72, 0·97). Older adults living larger distance tertiles from establishments with predominant sale of ultra-processed foods, mixed establishments or all categories of establishments had 16 % (PR = 0·84; 95 % CI = 0·73, 0·96), 19 % (PR = 0·81; 95 % CI = 0·71, 0·93) and 19 % (PR = 0·81; 95 % CI = 0·70, 0·94) lower prevalence of regular consumption of FV, respectively.Conclusion:The food environment is associated with regular consumption of FV among older adults. Longer distances from the residence of older adults to food establishments are independently associated with lower prevalence of regular consumption of FV.
Shelved Forever? How the Pandemic has Helped Flick the Digital Switch
Authors: Breslin Jas 
Published: December 2020

AbstractThis article argues that a migration from print resources to electronic access is required to democratise access to legal information for lawyers, and that resource managers should seize this opportunity to ‘go digital’ while lawyers are more accepting of change and open to new technologies as a result of forced changes to working practices during the Covid-19 pandemic. The author, Jas Breslin, a law library professional with 20-plus years of experience, explains how the sector is now grasping the nettle.
Saved by Dissections. The Popularity of Jigsaw Puzzles in Times of Calm and of Crisis. Are Librarians Dissectologists and What Might We Learn from the Bigger Picture?
Authors: Million Alison 
Published: December 2020

AbstractIn the 1760s a newly qualified apprentice to the King's Geographer hit upon the idea of cutting up maps for children to assemble as a geographical teaching aid. Dissected maps remain popular to this day in their evolved form as jigsaw puzzles. This article, written by Alison Million during the Covid-19 lockdown when jigsaws have exploded in popularity, looks at their history and at research projects which have established their cognitive benefits or have used them as an inexpensive non-digital tool. By considering papers written on librarians’ thinking styles and on personality it seeks to establish with the help of a short survey whether parallels might exist between the cognitive skillsets of the jigsaw puzzler and those of the librarian.
Kauri Tree‐Ring Stable Isotopes Reveal a Centennial Climate Downturn Following the Antarctic Cold Reversal in New Zealand
Authors: Pauly M. , Turney C. S. M. , Palmer J. G. , Büntgen U. , Brauer A. , Helle G. 
Published: December 2020

AbstractThe dynamics of the Late Glacial have been demonstrated by numerous records from the Northern Hemisphere and far fewer from the Southern Hemisphere (SH). SH paleoclimate records reveal a general warming trend, interrupted by a deglaciation pause Antarctic Cold Reversal (ACR; ∼14,700–13,000 cal BP). Here, we present decadal tree‐ring stable isotope chronologies (δ18O, δ13C) from New Zealand (NZ) subfossil kauri trees (n = 6) covering the post‐ACR millennium from 13,020 to 11,850 cal BP. We find a distinct, simultaneous downturn (∼12,625–12,375 cal BP) in all tree‐ring proxies paralleling regional tree growth declines, suggesting a widespread climate deterioration. This downturn was characterized by sustained high precipitation, low temperatures, and high relative humidity in NZ with incoming weather fronts from the South Ocean. Despite these promising results, questions remain about what drove the Kauri Downturn and how the hydroclimatic conditions were altered during this time period.
Comparison between the first and second mass eruptions from progenitors of Type IIn supernovae
Authors: Kuriyama Naoto , Shigeyama Toshikazu 
Published: December 2020

Context. Some massive stars experience episodic and intense mass loss phases with fluctuations in the luminosity. Ejected material forms circumstellar matter around the star, and the subsequent core collapse results in a Type IIn supernova that is characterized by interaction between supernova ejecta and circumstellar matter. The energy source that triggers these mass eruptions and dynamics of the outflow have not been clearly explained. Moreover, the mass eruption itself can alter the density structure of the envelope and affect the dynamics of the subsequent mass eruption if these events are repeated. A large amount of observational evidence suggests multiple mass eruptions prior to core collapse.
Aims. We investigate the density structure of the envelope altered by the first mass eruption and the nature of the subsequent second mass eruption event in comparison with the first event.
Methods. We deposited extra energy at the bottom of the hydrogen envelope of 15 M⊙ stars twice and calculated the time evolution by radiation hydrodynamical simulation code. We did not deal with the origin of the energy source, but focused on the dynamics of repeated mass eruptions from a single massive star.
Results. There are significant differences between the first and second mass eruptions in terms of the luminosity, color, and amount of produced circumstellar matter. The second eruption leads to a redder burst event in which the associated brightening phase lasts longer than the first. The amount of ejected matter is different even with the same deposited energy in the first and second event, but the difference depends on the density structure of the star.
Conclusions. Upcoming high cadence and deep transient surveys will provide us a lot of pre-supernova activities, and some of which might show multi-peaked light curves. These should be interpreted taking the effect of density structure altered by the preceding outburst events into consideration.
Edge-on boxes with X-features as parts of galactic bars
Authors: Patsis P. A. , Xilouris E. M. , Alikakos J. , Athanassoula E. 
Published: December 2020

Context. This paper is a contribution to the discussion about whether the X/peanut component is part of the bar, or the bar itself.
Aims. Our goal is to present a clear-cut case of a barred-spiral galaxy in which all structural components (i.e. the thick and thin part of the bar and the spiral arms) can be observed in its image and their dimensions directly measured there.
Methods. We obtained deep images of the nearby galaxy NGC 352, which has an ideal inclination allowing us to observe all of the parts that compose its morphology, estimate their relative sizes, and determine the topology of the luminous matter of this galaxy. We successfully compare our findings with the existence and the relative dimensions of the corresponding components encountered in the disc of a GADGET N-body model.
Results. NGC 352 is a barred spiral galaxy with a bar of about 13 kpc radius. Its bar has a central thick part that extends up to a distance about 5 kpc from the centre of the galaxy along its major axis, while its thickness reaches a height of 3.8 kpc. Thus, the thick part of the bar occupies the central part of the bar component, and its length is about 40% of that of the thin bar. The branches of the X-feature are characterised by the presence of ‘hooks’ at their extremities. The profile along the major axis of the bar is characterised by the presence of ‘shoulders’, the end of which is associated with local surface brightness enhancements on the equatorial plane. A central disc with a spiral-like feature embedded in it dominates in the innermost 1.7 kpc.
Conclusions. NGC 352 offers a case in which we directly observe that the X/peanut component is unambiguously part of the bar. This boxy structure is neither a separate bulge component nor the bar itself. The relative extent of the peanut with respect to the bar is well inside the range predicted in the majority of the simulated N-body bars. The hooks of the X-feature and the local surface brightness enhancements on the equatorial plane have their counterparts in surface density features of models based on the orbital theory, as well as of models based on response calculations and of fully selfconsistent N-body calculations.
Activation of Mechanoreflex, but not Central Command, Delays Heart Rate Recovery after Exercise in Healthy Men
Authors: Peçanha Tiago , de Brito Leandro Campos , Fecchio Rafael Yokoyama , de Sousa Patricia Nascimento , Silva Natan Daniel , Couto Patricia Guimaraes , de Abreu Andrea Pio , da Silva Giovanio Vieira , Mion Decio , Low David A. , de Moraes Forjaz Claudia Lucia 
Published: December 2020

AbstractThis study tested the hypotheses that activation of central command and muscle mechanoreflex during post-exercise recovery delays fast-phase heart rate recovery with little influence on the slow phase. Twenty-five healthy men underwent three submaximal cycling bouts, each followed by a different 5-min recovery protocol: active (cycling generated by the own subject), passive (cycling generated by external force) and inactive (no-cycling). Heart rate recovery was assessed by the heart rate decay from peak exercise to 30 s and 60 s of recovery (HRR30s, HRR60s fast phase) and from 60 s-to-300 s of recovery (HRR60−300s slow phase). The effect of central command was examined by comparing active and passive recoveries (with and without central command activation) and the effect of mechanoreflex was assessed by comparing passive and inactive recoveries (with and without mechanoreflex activation). Heart rate recovery was similar between active and passive recoveries, regardless of the phase. Heart rate recovery was slower in the passive than inactive recovery in the fast phase (HRR60s=20±8vs.27 ±10 bpm, p<0.01), but not in the slow phase (HRR60−300s=13±8vs.10±8 bpm, p=0.11). In conclusion, activation of mechanoreflex, but not central command, during recovery delays fast-phase heart rate recovery. These results elucidate important neural mechanisms behind heart rate recovery regulation.
Relationship Between Humeral Energy Flow During the Baseball Pitch and Glenohumeral Stability
Authors: Barfield Jeff W. , Wasserberger Kyle W. , Oliver Gretchen D. 
Published: December 2020

AbstractResearchers suggest that motion deriving energy from the more proximal segments of the body is important to reduce injury susceptibility. However, limited clinical assessments have been associated with efficient energy flow within a complex movement such as the baseball pitch. This research aimed to determine the relationship between glenohumeral stability as determined by the closed kinetic chain upper extremity stability test and energy transfer into and out of the humerus during the baseball pitching motion. Kinematic and kinetic data were collected at 240 Hz on twenty-four baseball pitchers. Participants performed the closed kinetic chain upper extremity stability test prior to throwing three fastballs at game speed to a catcher with the fastest fastball used for analysis. Spearman’s Rho were used to examine relationships between energy flow in and out of the humerus with glenohumeral stability as determined by the average score and normalized stance width during the closed kinetic chain upper extremity stability test. There was a significant negative correlation between the average score and normalized peak power leaving the humerus (r
s[22]=−0.42, p=0.04). This result provides preliminary support for the use of the closed kinetic chain upper extremity stability test as a clinical assessment of a pitcher’s ability to efficiently transfer energy within the upper extremity during the pitch.
A Generalized Equation for Prediction of VO2peak from a Step Test
Authors: Selland Corey A. , Kelly Joshua , Gums Kathleen , Meendering Jessica R. , Vukovich Matt 
Published: December 2020

AbstractThis study aimed to develop an equation to reduce variability of VO2peak prediction from a step test and compare VO2peak prediction from the new equation to the Queen’s College Step Test (QCST). The development group (n=86; 21.7±2 years) was utilized to develop the SDState step test equation to predict relative VO2peak. The cross-validation group (n=99; 21.6±2 years) was used to determine the validity of the SDState step test VO2peak prediction equation. A regression analysis was used to identify the best model to predict VO2peak. Analysis of variance (ANOVA) was further used to determine differences among predicted and measured VO2peak values. Forward stepwise multiple regression identified age, sex, abdominal circumference, and active heart rate at the 3-min mark of the step test to be significant predictors of VO2peak (mL·kg−1·min−1). No differences among measured VO2peak (47.3±7.1 mL·kg−1·min−1) and predicted VO2peak (QCST, 46.9±9.3 mL·kg−1·min−1; SDState 48.3±5.7 mL·kg−1·min−1) were found. Pearson correlations, ICC, SEE, TEE, Bland-Altman plots, and Mountain plots indicate the SDState step test equation provides less variation in the prediction of VO2peak compared to the QCST. The SDState step test equation is effective for predicting VO2peak from the YMCA step test in young, healthy adults.
Maßnahmen zur Verbesserung der allgemeinen ambulanten Palliativversorgung aus Sicht hausärztlicher Praxisteams
Authors: Zimansky Manuel , Gerdes Amrei , Schneider Nils , Stiel Stephanie 
Published: December 2020

Zusammenfassung
Hintergrund Zur Stärkung von AAPV fehlt es oftmals an Konkretisierung der Handlungsfelder für hausärztliche Praxisteams. Im Projekt „ALLPRAX“ wurde der Frage nachgegangen, welche Maßnahmen aus Sicht von Hausärzten und Medizinischen Fachangestellten das Potenzial haben, die AAPV in ihren jeweiligen Praxen zu verbessern.
Methode Acht Praxisteams wählten in jeweils einem Workshop anhand eines in einer vorherigen Projektphase entwickelten Maßnahmenkatalogs, geeignete Maßnahmen für eine Erprobung und Weiterentwicklung in ihrer eigenen Praxis aus.
Ergebnisse Die Praxisteams erachteten 35 aus 120 Maßnahmen für geeignet, die Palliativversorgung in ihrem Zuständigkeitsbereich zu verbessern. Am häufigsten wurden Maßnahmen zur vorausschauenden Versorgung von Patienten, Patienten- und Angehörigen-Beratung sowie Bildungsmaßnahmen für die Praxisteams ausgewählt.
Schlussfolgerung Zur Weiterentwicklung von AAPV in Hausarztpraxen bedarf es eines umfangreichen und zugleich differenzierten Interventionspakets.
Dosage of Anticoagulants in Obesity: Recommendations Based on a Systematic Review
Authors: Abildgaard Anders , Madsen Sofie A. , Hvas Anne-Mette 
Published: December 2020

AbstractAnticoagulants are frequently used as thromboprophylaxis and in patients with atrial fibrillation (AF) or venous thromboembolism (VTE). While obesity rates are reaching epidemic proportions worldwide, the optimal dosage for obese patients has not been established for most anticoagulants, including low-molecular-weight heparin (LMWH), non–vitamin K antagonist oral anticoagulants (NOAC), and pentasaccharides (fondaparinux). The aim of the present systematic review was to summarize the current knowledge and provide recommendations on dosage of LMWH, NOAC, and fondaparinux in obese patients (body mass index [BMI] ≥ 30 kg/m2 or body weight ≥ 100 kg). Based on a systematic search in PubMed and Embase, a total of 72 studies were identified. For thromboprophylaxis with LMWH in bariatric surgery (n = 20 studies), enoxaparin 40 mg twice daily, dalteparin 5,000 IE twice daily, or tinzaparin 75 IU/kg once daily should be considered for patients with BMI ≥ 40 kg/m2. For thromboprophylaxis with LMWH in nonbariatric surgery and in medical inpatients (n = 8 studies), enoxaparin 0.5 mg/kg once or twice daily or tinzaparin 75 IU/kg once daily may be considered in obese patients. For treatment with LMWH (n = 18 studies), a reduced weight-based dose of enoxaparin 0.8 mg/kg twice daily should be considered in patients with BMI ≥ 40 kg/m2, and no dose capping of dalteparin and tinzaparin should be applied for body weight < 140 kg. As regards NOAC, rivaroxaban, apixaban, or dabigatran may be used as thromboprophylaxis in patients with BMI < 40 kg/m2 (n = 4 studies), whereas rivaroxaban and apixaban may be administered to obese patients with VTE or AF, including BMI > 40 kg/m2, at standard fixed-dose (n = 20 studies). The limited available evidence on fondaparinux (n = 3 studies) indicated that the treatment dose should be increased to 10 mg once daily in patients weighing > 100 kg.
Rivaroxaban Compared to Placebo for the Treatment of Leg Superficial Vein Thrombosis: A Randomized Trial
Authors: Kearon Clive , Carrier Marc , Gu Chu-Shu , Schulman Sam , Bates Shannon M. , Kahn Susan R. , Chagnon Isabelle , Nguyen Doan Trang , Wu Cynthia , Rudd-Scott Lisa , Julian Jim A. 
Published: December 2020

AbstractThe role of rivaroxaban in the treatment of leg superficial venous thrombosis (SVT) is uncertain. This article aims to determine if rivaroxaban is an effective and safe treatment for leg SVT. Patients with symptomatic leg SVT of at least 5 cm length were randomized to 45 days of rivaroxaban 10 mg daily or to placebo, and followed for a total of 90 days. Treatment failure (required a nonstudy anticoagulant; had proximal deep vein thrombosis or pulmonary embolism; or had surgery for SVT) at 90 days was the primary efficacy outcome. Secondary efficacy outcomes included leg pain severity, and venous disease-specific and general health-related quality of life over 90 days. Major bleeding at 90 days was the primary safety outcome. Poor enrollment led to the trial being stopped after 85 of the planned 600 patients were randomized to rivaroxaban (n = 43) or placebo (n = 42). One rivaroxaban and five placebo patients had a treatment failure by 90 days (absolute risk reduction = 9.0%, 95% confidence interval: −22 to 5.9%). Leg pain improvement did not differ at 7 (p = 0.16) or 45 days (p = 0.89), but was greater with rivaroxaban at 90 days (p = 0.011). There was no difference in venous disease-specific (p = 0.99) or general health-related (p = 0.37) quality of life over 45 days. There were no major bleeds or deaths in either group. There were no identifiable differences in efficacy or safety between rivaroxaban and placebo in patients with symptomatic SVT but comparisons were undermined by a much smaller than planned sample size (NCT1499953).