bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survivorship Care Plans in Cancer: A Meta-Analysis and Systematic Review of Care Plan Outcomes
Authors: Hill Rebecca E. , Wakefield Claire E. , Cohn Richard J. , Fardell Joanna E. , Brierley Mary-Ellen E. , Kothe Emily , Jacobsen Paul B. , Hetherington Kate , Mercieca-Bebber Rebecca 
Published: October 2019

Abstract

Background
The Institute of Medicine recommends that survivorship care plans (SCPs) be included in cancer survivorship care. Our meta-analysis compares patient-reported outcomes between SCP and no SCP (control) conditions for cancer survivors. Our systematic review examines the feasibility of implementing SCPs from survivors' and health care professionals' perspectives and the impact of SCPs on health care professionals’ knowledge and survivorship care provision.

Methods
We searched seven online databases (inception to April 22, 2018) for articles assessing SCP feasibility and health care professional outcomes. Randomized controlled trials comparing patient-reported outcomes for SCP recipients versus controls were eligible for the meta-analysis. We performed random-effects meta-analyses using pooled standardized mean differences for each patient-reported outcome.

Results
Eight articles were eligible for the meta-analysis (n = 1,286 survivors) and 50 for the systematic review (n = 18,949 survivors; n = 3,739 health care professionals). There were no significant differences between SCP recipients and controls at 6 months postintervention on self-reported cancer and survivorship knowledge, physical functioning, satisfaction with information provision, or self-efficacy or at 12 months on anxiety, cancer-specific distress, depression, or satisfaction with follow-up care. SCPs appear to be acceptable and potentially improve survivors’ adherence to medical recommendations and health care professionals’ knowledge of survivorship care and late effects.

Conclusion
SCPs appear feasible but do not improve survivors’ patient-reported outcomes. Research should ascertain whether this is due to SCP ineffectiveness, implementation issues, or inappropriate research design of comparative effectiveness studies.
Helenistik kulelerde yanal yüke ilişkin düzlem içi ve düzlem dışı duvar davranışının duvar profilleri ve açıklık tiplerine bağlı olarak incelenmesi
Authors: GENÇER Funda , HAMAMCIOĞLU TURAN Mine , AKTAŞ Engin 
Published: October 2019

Taş bloklar arasında herhangi bir
bağlayıcı malzeme kullanılmadan inşa edilmiş olan kuru yığma duvar örgülerine
Yunan, Helenistik ve Roma dönemlerine ait farklı yapı tiplerinde
rastlanmaktadır. Yığma yapım sistemlerinin kurgularının, depreme ilişkin gerekliliklerin
deneyimler ile olgunlaşması sonucunda oluştuğu düşünülmektedir. Kuru yığma
duvar profilleri; duvar kalınlığı, cidar sayısı, cidarların bağlantısı, taş
blokların boyutu, formu, dizilişi ve ilişkileri açısından çeşitlilik
göstermektedir. Bu çalışmada Helenistik Dönem’de inşa edilmiş kuru yığma duvar
örgüsüne sahip, kareye yakın planlı gözlem kulelerinin depreme karşı dayanımını
arttıran detayların ortaya çıkarılması hedeflenmiştir. Çalışma; yanal yük
altında düzlem içi ve düzlem dışı duvarlarda meydana gelen şekil değişimlerinin,
farklı duvar profilleri ve açıklık düzenlerine sahip kuleler üzerinde
incelenmesiyle sınırlanmıştır.

Öncelikle; antik dönemde Karya, Pamfilya
ve Kilikya Bölgeleri’nde bulunan, yapısal özgünlük ve bütünlüğünü kaybetmemiş
ya da özgün bilgisi bulunan kuru yığma gözlem kulelerinin duvar profilleri ve
açıklık tipleri belgelenmiştir. Elde edilen veriler ile, farklı duvar
profillerine sahip, farklı açıklık tipleri bulunan hipotetik kuleler
tasarlanmıştır. Rijit bloklardan oluşan 3 boyutlu hipotetik kulelerin yanal
yüke ilişkin düzlem içi ve düzlem dışı duvar davranışının belirlenebilmesi için
denge durumuna (equilibrium) dayanan statik-benzeri
(quasi-static) eğme analizlerinin bilgisayar ortamında simülasyonu
yapılmış, kulelerin yıkılma açıları ve duvarlardaki şekil değişimleri
belirlenmiştir. Farklı duvar profilleri ve açıklık organizasyonlarına sahip
kulelerin; yanal yük altındaki davranışı incelenerek, kulelerin dayanımını
etkileyen özellikler saptanmaya çalışılmıştır.
Granüler yol malzemeleri için regresyon yöntemiyle Esneklik modülü (Mr) tahmin modeli geliştirilmesi
Authors: YILMAZ Altan 
Published: October 2019

Yol üstyapılarının mekanik-ampirik tasarımında
granüler malzemelerin mekanik direncinin tespiti amacıyla kullanılabilecek en
gerçekçi parametre Esneklik modülü olarak karşımıza çıkmaktadır. Esneklik
modülü uygulanan gerilme durumuna, yükleme süresine, su muhtevasına, kuru
yoğunluğa ve gradasyon gibi faktörlere bağlı olarak değişim göstermektedir.

Bu çalışma kapsamında, ülkemizdeki yol
inşaatlarında kullanılmakta olan volkanik kökenli agregalardan elde edilen
deneysel bulgular kullanılarak agrega karışımlarının Esneklik modülünü (Mr)
tahmin etmek amacıyla matematiksel bir model oluşturulmuştur. Çalışmada
kullanılan agrega örnekleri (bazalt ve traki-bazalt) Anadolu yarımadasının
güney ve iç bölgelerinden farklı ocaklardan temin edilmiştir. Çalışmanın
deneysel kısmında dinamik üç eksenli deneyi uygulanarak silindirik numunelerin
esneklik modülü bulunmuştur. Daha sonra elde edilen deneysel bulgular
kullanılarak matematiksel bir model oluşturulmuştur.

Çoklu regresyon yöntemiyle oluşturulan modelde,
agrega fiziksel özellikleri, agrega karışım özellikleri ve numune yükleme
durumu ile ilgili parametreler (8 farklı değişken) giriş verisi olarak alınmış
ve agrega karışımlarına ait Mr değeri çıkış parametresi olarak elde
edilmiştir. Yeni ortaya konan model, Uzan modeli gibi geleneksel tahmin
modellerine alternatif olarak ortaya konmuş ve bu modeller ile istatistiki
olarak karşılaştırılmıştır. Çoklu regresyon yöntemiyle elde edilen performans
değerleri oldukça yüksek çıkmıştır (R2:0,98,
SE:10,51). Model belirli değişkenler kullanılarak, yeni giriş değerleri için
sonuç üretebilmektedir. Bunun sonucu olarak, gerçek-zamanlı olarak farklı
gerilmeler altındaki esneklik modülü değerinin hesaplanabilmesini mümkün
kılmaktadır.
Exploring the Role of Computers in Knowledge Construction of Young Learners in a Constructionist Classroom
Authors: Joshi Archana , Darasawang Pornapit , Tepsuriwong Saowaluck 
Published: October 2019

This is an exploratory study which investigates a young learner constructionist classroom’s knowledge constructions by using computers. It is part of an on-going research which had ten participants ranging between 6-7 years of age. However, in this study only three participants out of the ten have been covered. The study was conducted in a project-based classroom where the participants had to build artefacts for knowledge construction. Data was collected through field observations, semi-structured interviews, learner journals and learner logs. The evidence of knowledge construction was found in the artefacts made by the participants. The results show that using computers to mediate the participants’ learning at different stages facilitated meaningful interactions between participants and peers and participants and facilitators, encouraged autonomy and provided itself as a source of information for exploration of ideas, which had a positive impact on participants’ knowledge construction.
Upper gastrointestinal endoscopy in patients with dysphagia: our experience
Authors: T. Zameerulla , D. Vivekanand , B. N. Hanumathappa 
Published: October 2019

Background: One of the common indications for upper gastrointestinal (GI) endoscopy is dysphagia. Dysphagia is usually associated with serious underlying disorder that requires immediate attention. The current study aimed to determine the frequency of common endoscopic findings in patients presenting with dysphagia.Methods: This retrospective study was conducted at the S.S Institute of Medical Science and Research center Davangere from January 2015 to June 2019. Patients admitted with complaints of dysphagia, OPD patients and references with complaints of dysphagia underwent upper GI endoscope by different endoscopist were included in the study. Register in endoscopic room was referred for different endoscopic findings in dysphagia patients.Results: A total of 158 patients presenting with dysphagia were studied, 83 (52.53%) were males and 74 (47.46%) were females. The mean age was 55years. Normal study present in 63 (39.87). Malignant oesophageal stricture was the next common finding noted in 47 (29.74%) patients. Among these patients 25 (53.19%) males and 22 (46.80%) females patients. It was followed by reflux esophagitis in 31 (19.62%) patients. Benign oesophageal strictures in 9 (5.69%) patients while achalasia was noted in 1 (0.63%) patients, 7 (4.46%) patients had findings other than the ones mentioned above. Malignant lesions commonly present in elderly patients with age. Benign lesions present commonly in younger age group.Conclusions: Malignancies, reflux esophagitis, benign oesophageal strictures are a more common cause of dysphagia in our population. Early diagnosis of can result in proper treatment of many of these cases.
Delayed presentation of extensor pollicis longus tendon injury treated using extensor indicis proprius tendon transfer
Authors: Ghelani Nilesh B. , Shah Sankit , B. P. Sunmathi , Patel Samir 
Published: October 2019

Spontaneous closed rupture of EPL tendon are frequently associated with rheumatoid arthritis, Colles fracture, sports related injury. In cases of delayed presentation direct tendon repair is not feasible and a tendon transfer is usually recommended. In this study we evaluated the results of extensor indicis proprius (EIP) to extensor pollicis longus (EPL) transfers for EPL ruptures. Four patients, (two male and two females); mean age 32 years (range 20 to 45 years) with EPL tendon rupture underwent EIP to EPL tendon transfer. The mean duration from rupture to surgery was 4.5 weeks (range 4 to 6 weeks). Range of motion of the metacarpophalangeal (MCP), interphalangeal joints (IP) of the thumb and index finger of the operated side was compared with the normal side. The results were scored using geldmacher scheme, for the thumb four functions were scored, the radial abduction angle, the elevation deficit, the opposition distance and flexion extension deficit of MP and IP joints. The mean follow-up period was 5 months. All the four patients were able extend the thumb at MCP joint and oppose the thumb to the MCP of little finger after mean follow up of 5 months. Based on the questionnaire, the results of tendon transfer scored by three (75%) patients was excellent and by one (25%) patient was good. Independent extension of the index finger of operated hand was possible in all 4 patients. The procedure of EIP to EPL tendon transfer provides excellent result for extension of thumb. It is a safe procedure.
Smallpox: leaving its mark on public health
Authors: Moore Corey B. 
Published: October 2019

Smallpox was one of the most lethal human pathogens in history. It originated around 10,000 years before common era (BCE) in North-eastern Africa, and spread world-wide through human migration and increasing population densities with periodic epidemics throughout the world. By the middle of the 18th century, around one million Europeans each year were contracting the disease with approximately one third of adults and 90 percent of infants succumbing to it. The mortality rate in the immune-naïve populations of the Aztecs and the Incas were as high as 90%. Survivors were left with disfiguring scars and one third were blinded. After the bubonic plague, it was the most feared disease. It affected the outcome of many wars, conquests and the development of many civilisations.
SOCIOLOGICAL MONITORING OF THE QUALITY OF DENTAL CARE FOR EMPLOYEES IN A CLOSED INDUSTRIAL ENTERPRISE
Authors: Березин Вениамин , Berezin Veniamin , Шулаев Алексей , Shulaev Aleksey , Старцева Елена , Statseva Elena , Березин Константин , Berezin konstantin 
Published: October 2019

Subject. The article examines the results of the sociological survey and questionnaire of employees of the special economic zone "Alabuga" of the Republic of Tatarstan, including the analysis of data on the organization, quality and availability of dental care at work.
Purpose of the research is to determine the satisfaction level of the industrial enterprise`s employees with the quality of dental care.
Material and methods. Such methods as sociological survey, questionnaire, statistical analysis of the data are used in accordance with the aim and objectives of this study. The sampling included 370 questionnaires consisting of 13 general questions characterizing the social status, awareness of the quality of dental care, as well as their need for various types of dental services.
Results. According to the results of the the survey, it has been found out that 63.0% of the company`s employees sought dental treatment if necessary, 23.5 and 13.5 % of those interviewed accordingly underwent dental examination 1 or 2 times a year, the need to consult a dentist was revealed in 49.9 % respondents. Unsatisfactory conditions of the fundamental substance of the teeth and the level of hygiene of the oral cavity were reported by 31.6 % and 25.4 % of the respondents correspondingly, the satisfactory conditions were reported by 4.3% and 17.8 % of the employees, 14.6 % of respondents were undecided on the issue of assessing the condition of the teeth and gums. The questionnaire survey showed the absence of information concerning individual treatment plans and prevention methods (28.1 %), 71.6 % of the respondents indicated the presence of knowledge about the guaranteed dental care by the compulsory health insurance, as 28.4 % of the respondents reported the lack of knowledge. The study revealed a large percentage of respondents in need of a consultation by a dentist. Subjective assessments of dental health were characterized by a high proportion of uncertain responses, which may explain the low level of survey`s data of respondents.
Summary. The conducted sociological survey allowed to determine the directions of improvement of dental care among the employees of the special economic zone "Alabuga" of the Republic of Tatarstan.
CAUSES, DIAGNOSIS AND TREATMENT OF MAXILLARY SINUSITIS, THE CURRENT STATE OF THE PROBLEM
Authors: Дрегалкина Анна , Dregalkina Anna , Костина Ирина , Kostina Irina , Салий Ольга , Salii Olga 
Published: October 2019

Object. Patients with inflammatory diseases of paranasal sinuses make up about 1/3 of the total number of patients admitted to hospitals with diseases of the upper respiratory tract.
The aim of the study was to describe the causes and methods of treatment of maxillofacial sinusitis according to the Department of maxillofacial surgery and otorhinolaryngology SB "SOKB № 1" AND compare them for the periods from 2006 to 2007 and from 2015 to 2018 g.
Methodology. A retrospective study of nosology according to the annual reports and protocols of operating journals, patient histories of the Department of maxillofacial surgery and otorhinolaryngology SB "SOKB № 1" FOR the periods from 2006 to 2007, and from 2015 to 2018.
Results. Over the investigated period, the proportion of hospitalized patients with sinusitis increased 1.9 times. Between 2016 and 2017, 2.7 times more patients with chronic sinusitis and rhinosinusitis were hospitalized than in 2006-2007. The number of hospitalized patients with acute sinusitis decreased significantly (9.5 times). The frequency of chronic inflammation in the maxillary sinus is 3.3-7.4 times higher than in other paranasal sinuses. Women predominate among patients with sinusitis. The age of patients with sinusitis is varied, but middle-aged and young people make up the majority. Analysis of factors of infection of the maxillary sinus showed that the most common cause of inflammation of the maxillary sinus in hospitalized patients were foreign bodies and perforations of the bottom of the sinus when removing the upper teeth. The analysis of surgical treatment methods of chronic maxillary sinusitis in different years showed that in 2006-2007 Caldwell—Luke sinusotomy prevailed, and now – endoscopic sinusotomy.
Conclusion. Pathology of maxillary sinuses requires a comprehensive approach of an otorhinolaryngologist, dentist and maxillofacial surgeon in matters of diagnostic and therapeutic tactics.
LABORATORY-CLINICAL SUBSTANTIATION OF ATRAVMATICITY OF USING INDIVIDUAL HEALING ABUTMENT OF THE AUTHOR'S DESIGN
Authors: Нерсесян Петрос , Nersesyan Petros , Жолудев Сергей , Zholudev Sergey , Базарный Владимир , Bazarnyy Vladimir , Полушина Лариса , Polushina Larisa , Максимова Арина , Maksimova Arina , Жолудев Денис , Zholudev Denis 
Published: October 2019

Subject. To improve the effectiveness of prosthetics for tooth loss, an abutment is proposed, which is used both as an artificial crown and a gum former, which is especially important for prosthetics in the frontal group of teeth. An analysis was made of the local content of matrix metalloproteinases (MMP) 8 and 9 and their tissue inhibitor (TIMP) and buccal cytology in patients before and after dental implantation surgery using the author's technique and the traditional protocol.
Objective ― to evaluate the effectiveness and non-invasiveness of using the author’s abutment design under immediate loading by evaluating oral homeostasis and the level of cell proliferation.
Methodology. Three groups of patients were examined: the main of 25 patients from 30 to 60 years old, who used the original technique, comparisons - 40 patients of the same age, where prosthetics and implantation were performed according to the traditional two-stage protocol and a control group of 40 somatically preserved patients of the same age, which do not require dental prosthetics. In all groups, MPP 8, 9, TIMP were studied, and the buccal cytology was also evaluated.
Results. The pathogenetic role of disorders of the connective tissue matrix in the development of early complications of dental implantation was revealed.
Findings: Laboratory studies and clinical observations of patients of the main group and the comparison group indicate the effectiveness and non-invasiveness of the original methods of prosthetics on implants using an individual abutment with a gingiva shaper.
The course of chronic heart failure in patients with early rheumatoid arthritis on the anti-rheumatic therapy
Authors: Kirillova I. G. , Novikova D. S. , Popkova T. V. , Udachkina H. V. , Markelova E. I. , Gorbunova Yu. N. , Korsakova Yu. O. 
Published: October 2019

Objective: To evaluate the effect of the “treat to target” anti-rheumatic therapy on the course of chronic heart failure (CHF) in patients with early rheumatoid arthritis (RA). Materials and methods: The study included 22 patients (17, or 77% female) with CHF with valid diagnosis of RA (ACR/EULAR criteria, 2010), median (Me) age of 60 years, and median disease duration of 7 months. Ten patients (45%) were seropositive for IgM rheumatoid factor and 22 (100%) had antibodies to cyclic citrulline peptide. Their median (1st; 3rd quartiles) DAS28 was 5.6 [4.8; 6.5]. The diagnosis of CHF was confirmed in accordance with the guidelines on the diagnosis and treatment of CHF by the Russian Society of Specialists in Heart Failure (2013). NT-proBNP levels were measured by electrochemiluminescence (Elecsys proBNP II, Roche Diagnostics, Switzerland). All patients were started on subcutaneous methotrexate (MT) with rapid dose titration to 30 mg weekly. If the MT was insufficiently effective, a biological disease-modifying antirheumatic drug (bDMARD) was added to the therapy after 3 months, mainly a TNF-alpha inhibitor. After 18 months, 10 (45%) patients were in remission and had low disease activity, 6 (60%) patients underwent MT therapy in combination with bDMARDs. Results: At baseline, 21 (95%) patients were diagnosed with CHF with preserved ejection fraction and one patient had CHF with reduced ejection fraction. After 18 months there was an improvement of clinical symptoms, echocardiographic parameters (reduction of the left atrium diameter and the left atrium end-systolic volume index, IVRT, E'LV), and diastolic function of the left ventricle (LV). No episodes of acute CHF deterioration were registered. LV diastolic function normalized in 7 (32%) patients who reached the target level of blood pressure, remission (n=5) and low disease activity (n=2), mainly under the treatment with MT and bDMARDs. In patients with RA and CHF, the NT-proBNP levels decreased from 192.2 [151.4; 266.4] to 114.0 [90.4; 163.4] pg/ml (p<0.001) and became normal in 16 of 22 (73%) patients (p<0.001) with remission or low RA activity. In 5 (22%) patients, clinical CHF manifestations resolved, LV diastolic function and NT-proBNP levels were normalized. Conclusion: In the patients with early RA and CHF anti-rheumatic therapy improves the clinical course of CHF, LV diastolic function and reduces NT-proBNP levels.
Murathan Mungan’ın Şairin Romanı İsimli Eserinin Yapısalcı Metodoloji Çerçevesinde İncelenmesi
Authors: YAZBAHAR Zehra 
Published: October 2019

Edebî
eseri anlamak ya da anlamlandırmak için ortaya atılan pek çok yöntem ve kuram
vardır. Esere anlam kazandırmaya çalışan bu yöntemlerden biri de yapısalcılıktır.
Batı dünyasında “structuralism” olarak bilinen, temelinde Rus biçimciliğinin
olduğu ve 20. yüzyılda ortaya çıkan yapısalcı yöntemde incelenen herhangi bir
nesnenin kendi içinde anlaşılabilir olmasını sağlamak esastır. Genel hatlarıyla
nesneyi “yapı” kavramından hareketle açıklamaya çalışan bu kuramın özünü
oluşturan ana öge, yapıdır. Edebî eser
bazında düşündüğümüzde ise her eser, bütünlük arz eden çeşitli yapı
unsurlarından oluşur. Eserde anlam bütünlüğünü sağlayan yapıyı “anlatıcı”, “olay
örgüsü”, “kişiler”, “zaman”, “mekân”, “dil ve üslup” gibi unsurların meydana
getirdiği söylenebilir. Yapısalcılık
kuramı doğrultusunda Murathan Mungan’ın
2011 yılında yayımlanan Şairin Romanı
isimli eserinin ele alındığı bu çalışmada söz konusu eser, “anlatıcı ve anlatma
yöntemi”, “içerik”, “olay örgüsü ve vaka takdimi”, “dil ve üslup” unsurları
yönünden incelenmiştir. Diğer bir ifadeyle yapı unsurları arasındaki ilişki
verilerek romanın kurgusal özellikleri tespit edilmeye çalışılmış ve romanın
yapısal çözümlemesi yapılmıştır.