bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical Simulation on the Cavity-Induced Boundary Layer Transition
Authors: Guo Peixu , Gao Zhenxun , Jiang Chongwen , Lee Chun-Hian 
Published: May 2020

Abstract
The boundary layer transition can be triggered in either natural or forced way. In this paper, a Mach 3 cavity-induced boundary layer transition is simulated using the implicit large eddy simulation, in order to study the transition caused by the surface gap on the vehicles in the real condition. One of the characteristics of this paper is that no disturbance is imposed in the inflow condition such that the boundary layer transition is triggered by the self-sustained fluctuation in the upstream cavity. Results show that the transition appears in the natural scenario and the stage of the linear instability seems to be followed by the process of the secondary instability. Linear stability analyses are also utilized to show the development of the unstable modes.
A modified active disturbance rejection control for fast steering mirror in aerospace application
Authors: Zheng Xintao , Huang Hai , Li Weipeng 
Published: May 2020

Abstract
Active disturbance rejection control (ADRC) has proved to be an effective tool in dealing with engineering problems related to the plant along with dynamic uncertainties, disturbances, nonlinearities. A modified active disturbance rejection control (MADRC) method is proposed to design the Fast Steering Mirror (FSM) controller. The modified extended state observer (ESO) incorporate with identified plant information is employed to reject the disturbances, nonlinear factors and modelling errors which meant to constraint the plant to a nominal form. Therewith, an well-designed analytical method is introduced to calculate the parameters of a feedback loop to force the plant response like a pre-designed model. Besides, a Lead-Leg Controller (LLC) consisting of two Tracking-Differentiator (TD) is designed to improve the performance of the controller. LLC generates a filtered output based on the expected plant dynamics to increase the FSM bandwidth, and LLC can also help to improve the stability of the system by restricting the tracking error in a limited range when there is an abrupt command input. The MADRC strategy is proven an effective solution for FSM. Simulation results show that the MADRC method can achieve a excellent performance without tedious tuning work. The experiment results proved the validation in practical application.
Effect of different manual brewing techniques to the sensory profile of the Indonesian Arabica and Robusta “natural coffees”
Authors: Sunarharum W B , Ahmad R , Primadiani E 
Published: May 2020

Abstract
The “natural coffee” produced through sun-drying has been a common coffee post-harvest processing practice and well-known to exhibit specific sensory characters. However, the sensory profile of coffee in a cup could be influenced by many other factors including the brewing techniques. The objective of this research was to study the effect of different manual brewing techniques i.e. Indonesian “tubruk” method, Vietnam drip, cold brew, and aero press to the sensory profile of two Indonesian “natural coffees” origin i.e. Robusta Gayo and Arabica Kerinci. Evaluation was performed on 33 sensory attributes using Sensory Descriptive Analysis method employing 10 trained student panellists. Data analysis was performed using Minitab 17 and the Unscrambler® X MVA software. The result showed that in total; as many as 21 attributes were rated by the panellist. The two samples showed different sensory profiles, particularly in some sensory attributes assessed. The different manual brewing techniques was also found to have significant impact (α = 0.05) on 17-18 sensory attributes, showing that each technique will be responsible for certain sensory characters perceived by coffee consumer.
The physical properties of coffee caviar as influenced by sodium alginate concentration and calcium sources
Authors: Sunarharum W B , Kambodji A D , Nur M 
Published: May 2020

Abstract
Coffee caviar is a product of spherification technique, which is one of well-known technique in molecular gastronomy. Spherification is a process when liquid turns into spheres in a bath due to the reaction such as between sodium alginate, calcium chloride, and calcium lactate in the gelation process. The objectives of this study are to know the effect of different formula used for caviar making to the physical characteristics of coffee caviar, and to choose the best formula for coffee caviar. Research was conducted under Randomized Block Design involving two variables i.e. the different concentration of sodium alginate (1%, 1.5% and 2 %) and different calcium sources (calcium lactate or calcium chloride). Evaluation was performed on the coffee-alginate solution (alginate sol) for viscosity, color (L*a*b*), total soluble solids, and pH, while the produced caviar was analyzed for texture, syneresis, as well as sensory properties (appearance, color, aroma, flavor, texture, overall liking, chewiness and gel strength). The result showed that the physical characteristic of the coffee caviars were diverse depending on the different formula used. The sodium alginate concentrations and calcium sources had significant effects (α=0.05) on the caviar texture, chewiness and gel strength. The best proportion for coffee caviar based on Derringer’s desirability function was 1.5% concentration of sodium alginate with the use of calcium chloride as calcium ions sources.
Viability of Crassocephalum crepidioides seeds due to Boron application
Authors: Lestari M W , Mardiyani S A , Murwani I , Ulfah M 
Published: May 2020

Abstract
Boron (B) is a microelement that is needed in plant growth, because it plays an important role in the production of grain, increases carbohydrate transport and increases enzyme activity, if it is given in the appropriate amount. This study aimed to determine the concentration of Boron to obtain the best viability of the seeds of Crassocephalum crepidioides. The research was conducted at the greenhouse, using Random Block Design. The treatment was the concentration level of Boron, consisting of four levels (0%, 50 mg/L, 100 mg/L, and 150 mg/L), carried out in triplicate. The observed variables included the number of flowers (florets), number of seeds per flower, seed germination (%), speed of seed germination, and growth potential (%). The results showed that the number of flowers and the number of seeds per floret was not significantly different for all treatments tested. Boron concentration of 150 mg/L produces better performance in seed germination, speed of seed germination, and growth potential.
Antioxidant activity optimisation of young Robusta coffee leaf kombucha by modifying fermentation time and withering pre-treatment
Authors: Fibrianto K , Zubaidah E , Muliandari N A , Wahibah L Y , Putri S D , Legowo A M , Al-Baarri A N 
Published: May 2020

Abstract
Kombucha is a fermented drink made from liquid tea. The fermentation is involving bacteria and yeast called Symbiotic Culture of Bacteria and Yeast (SCOBY) The current study aims to investigate the possibility of young Robusta coffee leaf tea as a raw material for kombucha, by optimizing its antioxidant activity and applying withering pre-treatment. The Response Surface Methodology (RSM) was applied to design the observation up to 21 days. Within the duration of fermentation, the optimum IC50 was observed on the third days of fermentation. The results showed that withering treatment significantly affect the pH values, total sugar, total phenolic content, and IC50 of young coffee leaf kombucha. The sensory quality also shows that 5 out of 19 attributes, including brown color, sour taste, bitter taste, alcoholic aroma, sour aroma were also affected by the treatment (p-value<0.05). Regardless the chemical and sensory qualities, the kombucha was still significantly accepted (p-value<0.05) by the respondents.
Analysis of pulsed electric field (PEF) specific input energy and its effect to the tannin content of Areca (Areca catechu L.) seed powder extract
Authors: Rahmah N L , Sukardi  , Ahsan A M 
Published: May 2020

Abstract
Areca (Areca catechu L.) is one of the plants that contain phenolic compounds as tannin as antioxidant. Pre-treatment priorplant extraction using Pulsed Electric Field (PEF) has been reported to improve the yield and the qualityof the extracts. The specific input energy of PEF, counted an energy needed during the PEF process, was found to be influenced by voltage and duration of PEF. In this study, the relationship between specific input energy using variation voltage and duration of PEF was studied on extraction of areca seed. This research examined tannin levels and changes in areca cell structure before and after PEF. This research used Factorial Randomized Block Design with two factors. The first factor was PEF voltage with three levels of 3, 4 and 5 kV and the second factor was PEF duration with three levels of 3, 5 and 7 minutes. The obtained data was analyzed using one-way ANOVA. The results revealed that specific input energy of PEF in the range of 1.92-12.44 kJ/cm3did not have significant effects ontannin content of areca seeds extract. However, when it compared with control (without PEF pretreatment), better results was obtained on the tannin content. Scanning Electron Microscopy-Energy Dispersive X-ray (SEM-EDX) analysis of areca seed powder demonstrated significane differences in structure and element concentration of samples with and without PEF pretreatment. The findings confirmed that PEF pretreatment offers great promise in tannin extraction.
The influence of temperature in swelling power, solubility, and water binding capacity of pregelatinised sweet potato starch
Authors: Ulfa G M , Putri W D R , Fibrianto K , Prihatiningtyas R , Widjanarko S B 
Published: May 2020

Abstract
Sweet potato is a common tuber in Indonesia, however it is less popular than cassava and corn. Sweet potato is alsorich for starch that can be used for many industrial applications, although it still have many drawbacks in native form. Pregelatinization can be used to overcome those drawbacks and increase its value. The swelling power (SP), solubility (S), and water binding capacity (WBC) of pregelatinized white sweet potato starch were analyzed. The starch were pregelatinized with different temperature at 35, 40, 45, 50, 55, 60°C. The swelling power and solubility of sweet potato starch ranged from 16.26-30.30 g/g and 1.58-26.39 %, respectively. Moreover, the WBC obtained are 76.07-232.37 %. Pregelatinized sweet potato starch showed a higher SP, S, and WBC as the increasing of temperature until some point. The variation obtained in the starches’ properties was important for some industrial requirements.
The changing profiles of organosulfuric compounds during black garlic processing
Authors: Ammelia S M , Suharti  , Retnosari R , Utomo Y , Sukarianingsih D , Wonorahardjo S 
Published: May 2020

Abstract
Black garlic is popular as food supplement as well as herbal medicine due to its rich and beneficial chemical contents. However, the chemical changes during the process are rarely investigated. The purpose of this study was to determine the effect of heating time on sulfur-containing compound profiles and antioxidant activity during fermentation process at 60°C by solvent extraction followed by GC-MS analysis, as well as antioxidant activity, using DPPH method. The result indicated that black garlic underwent changes of sulfur-containing organic secondary metabolites, such as allicin and its derivative compounds. The process also increased antioxidant activity in black garlic.
Effect of drying techniques on microstructure and functional properties of tragacanth-insulin microparticles
Authors: Nur M 
Published: May 2020

Abstract
Numerous antimicrobials, hormones and enzymes as bioactive peptides/proteins could take advantage of oral delivery. Microparticles produced by complexation of two polyelectrolytes may have prospective use as a carrier for oral administration of proteins/peptides. Food polysaccharides like alginate, carrageenan, pectin, tragacanth and dextran can be potential excipients for this purpose. In this research, microparticles were created by the inclusion of bioactive protein/peptides into a tragacanth hydrogel accompanied by drying process. Insulin was utilized as a bioactive proteins model. Bioactive protein and tragacanth microparticles created at various pH and drying methods (freeze drying and spray drying) were assessed by SEM analysis and ATR Fourier transform infrared (ATR FTIR). The SEM study revealed that sub spherical microparticle was produced using spray drying process while the porous structure was produced using the freeze-drying method. In FTIR study, the complexes between tragacanth and insulin displayed amide absorption bands appearing in the protein spectra and exhibited the formation of new chemical substances. This finding indicates that both spray and freeze dried microparticles may act as a potentially promising device for oral delivery of bioactive proteins and peptides
Performance analysis and traceability system using SCOR method in the orange fruit supply chain of Citrus reticulata Blanco (Case study in Batu City, East Java)
Authors: Kamal M A , Kurniawan M , Santoso I 
Published: May 2020

Abstract
Orange Fruit Batu 55 is a typical plant from the Batu City East Java in addition to apple plants. This orange has the advantage of sweet, fresh and harvest times 3 times a year. The level of competition is quite high in the market, making the Batu 55 tangerine fruit must be able to survive especially in facing the competition with imported products. Increasing the level of dependence and complexity of the current supply chain network makes supply chains as a whole more vulnerable to disruption. This study aims to describe the supply chain using the framework of the Food Supply Chain Network, measure supply chain performance, and identify the implementation of traceability systems of specific strain of Citrus reticulata Blanco namely Keprok Batu 55.
Determination pollution load capacity of Ngrowo River as wastewater receiver from hospital activities
Authors: Lusiana N , Rahadi B , Anggita Y 
Published: May 2020

Abstract
Industrialization and domestic activities very potentially to contribute water pollution addition especially into a river. One of domestic activities that may produce wastewater is a hospital activity. Public Regional Hospital in Tulungagung is located at Kedungwaru that will developed in order to further support the existing infrastructure. Assessment towards water quality and load pollution capacity of Ngrowo River as wastewater receiver is very important before hospital development began. The method used in this research was mass balance method, pollution index to determine of water pollution status based on the parameters of temperature, pH, total suspended solids (TSS), dissolved oxygen (DO), biochemical oxygen demand (BOD), chemical oxygen demand (COD), nitrate and phosphate. The quality parameters obtained in this study were compared with the class II water quality standard. The maximum pollutant load was calculated to determine the pollution load capacity. The result show that water quality of Ngrowo River was categorized in low pollution (around 3.75 – 3.99 for index pollution) based on class of II of water quality standard. Load pollution capacity at downstream have exceeded 28,673.3 kg/day for BOD and 34,339.3 kg/day for COD in existing condition. Based on the findings in this study, it is recommended that hospitals are obliged to have wastewater treatment plant installed. Such approach is critical to maintain the quality of surroundings environments as well as to prevent water pollution to occur.
Computational study of the potential of phenolic acids berries as an inhibitor of aldose reductase for diabetes mellitus treatment
Authors: Purnamasari V , Estiasih T , Sujuti H , Widjanarko S B 
Published: May 2020

Abstract
Berries are known to contain bioactive compounds that can function physiologically to optimise health status. One type of bioactive compound found in berries is phenolic acid. Fruits are known to have activities to inhibit aldose reductase (AR). Inhibition of AR can control of microvascular complications of diabetes mellitus, such as blindness, nephropathy and neuropathy. But some AR inhibitors show side effects due to cross-reactions with analogous enzymes, so the purpose of this study is to predict the ability of phenolic acids berries binding to AR and predict selectivity of berries phenolic acids as AR inhibitor through in silico studies. The inhibition activity of twelve berry phenolic acids on AR was analysed using in silico and compared with epalrestat as a commercial AR inhibitor. The phenolic acids were docked to AR using Autodock Vina in PyRx 0.8. 3D molecular interactions visualized using PyMOL were then analyzed with LigPlot+. Chlorogenic acid and neochlorogenic acid show binding energy are higher affinity (-8.0 and -8.3 kcal/mol) than binding energy of epalrestat as a commercial AR inhibitor. The orientation of chlorogenic acid and neochlorogenic acid with the active side of AR showed that the binding of two compounds on the active side of AR occupies the same position as the binding position of epalrestat. Analysis of the interaction of the chlorogenic acid and neochlorogenic acid with AR indicates binding occurs in the pocket specificity of the active side of AR, so indicates that the two compounds have the potential as AR inhibitors.
The conversion of lignocellulosic biomass to bioethanol: pretreatment technology comparison
Authors: Wardani A K , Tanaka N C , Sutrisno A 
Published: May 2020

AbstractThe barrier to realising the potential of lignocellulosic bioethanol is the recalcitrance of cellulosic biomass. Overcoming this biomass recalcitrance is the key challenge to large scale production of lignocellulosic bioethanol. Pretreatment is an important and critical step that enables enzyme hydrolysis of lignocellulose conversion to ethanol. Finding a pretreatment method for reducing the high recalcitrance via cost-effective pretreatment methods would therefore be of great benefit. This study aims at investigating the effect of pretreatment on delignification process of sugarcane bagasse and oil palm trunk. Two methods of pretreatment were compared i.e. alkaline hydrogen peroxide pretreatment (1% and 5% H2O2) and subcritical water pretreatment (170°C, 2.2 MPa) for the effectiveness of reducing the lignin content. Scanning Electron Microscopy (SEM) analysis was also performed to investigate the effect of pretreatment on surface of lignocellulosic biomass. It was observed that alkaline hydrogen peroxide pretreatment gave better results than subcritical water pretreatment based on the lignin content for both lignocellulosic biomass. Pretreated sugarcane bagasse presented lower lignin content than pretreated oil palm trunk. Lignin was successfully removed until 56.99% under the best condition of 5% of alkaline hydrogen peroxide, at 28°C for 72 hours incubation. This study confirmed that alkaline pretreatment was found to have a better method for the conversion of lignocellulosic materials. Furthermore, sugarcane bagasse has a greater potential as basic raw materials used for the bioethanol production than oil palm trunk because it has lower content of lignin with higher content of cellulose.
Cognitive health expectancies of cardiovascular risk factors for cognitive decline and dementia
Authors: Zheng Lidan , Matthews Fiona E , Anstey Kaarin J 
Published: May 2020

Abstract

Background
Cognitive health expectancy estimates the proportion of the lifespan that is lived in good cognitive health at the population level. A number of cardiovascular diseases have been identified to be risk factors for cognitive decline and dementia including diabetes, stroke, heart diseases and hypertension. The aim of this study was to examine how these cardiovascular conditions relate to cognitive health expectancy.

Methods
Longitudinal data were obtained from the US Health and Retirement Study. Multistate modelling was used to estimate total life expectancy (LE), cognitive impairment free life expectancy (CIFLE) and years spent with cognitive impairment (CILE) across self-reported diabetes, hypertension, heart problems and stroke. Individual and cumulative effects of multiple cardiovascular conditions were examined.

Results
The presence of cardiovascular disease was associated with a 5- to 9-year decrease in LE and 4- to 8-year decrease in CIFLE at age 55. The outcomes varied in a hierarchical fashion by cardiovascular condition. Relative to other conditions, individuals with stroke had the shortest LE and CIFLE. Analysis of multiple cardiovascular risk factors revealed that each additional cardiovascular condition was associated with an exponential decrease in LE and CIFLE.

Conclusions
Having a cardiovascular condition is associated with a lower CIFLE and higher proportion of life lived with cognitive impairment. However, the outcomes vary depending on the type of cardiovascular condition. Reducing incidence of stroke and minimising exposure to multiple cardiovascular risk factors may be beneficial in helping to improve population estimates of cognitive health expectancy.
Practice-enhancing publications about the medication-use process in 2018
Authors: Vest Tyler A , Gazda Nicholas P , Schenkat Daniel H , Eckel Stephen F 
Published: May 2020

Abstract

Purpose
This article identifies, prioritizes, and summarizes published literature on the medication-use process (MUP) from calendar year 2018 that can impact health-system pharmacy daily practice. The MUP is the foundational system that provides the framework for safe medication utilization within the healthcare environment. The MUP is defined in this article as having the following steps: prescribing/transcribing, dispensing, administration, and monitoring. Articles that evaluated one of the steps were gauged for their usefulness toward daily practice change.

Summary
A PubMed search was conducted in February 2019 for articles published in calendar year 2018 using targeted Medical Subject Headings (MeSH) keywords, targeted non-MeSH keywords, and the table of contents of selected pharmacy journals, providing a total of 43,977 articles. A thorough review identified 62 potentially significant articles: 9 for prescribing/transcribing, 12 for dispensing, 13 for administration, and 28 for monitoring. Ranking of the articles for importance by peers led to the selection of key articles from each category. The highest-ranked articles are briefly summarized, with a mention of why they are important within health-system pharmacy. The other articles are listed for further review and evaluation.

Conclusion
It is important to routinely review the published literature and to incorporate significant findings into daily practice. This article assists in identifying and summarizing recent impactful contributions to the MUP literature. Health-system pharmacists have an active role in improving the MUP in their institution, and awareness of significant published studies can assist in changing practice at the institutional level.