bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of genes and metabolites associated with propamocarb hydrochloride response in tobacco
Authors: Yang Huijuan , Zhang Yuning , Shi Hongzhi 
Published: July 2020

AbstractPropamocarb hydrochloride is a systemic fungicide used against Pythium and Phytophthora as well as other diseases in tobacco. This study aimed to understand the response of tobacco to propamocarb hydrochloride treatment at the transcriptome and metabolome levels. Transcriptomic and metabolomic analyses were conducted on tobacco leaves treated with or without propamocarb hydrochloride to identify differentially expressed genes (DEGs) and differential metabolites, which were used for further functional enrichment analyses. In all, 1364 to 2497 DEGs and 34 differential metabolites were identified in different comparable groups. The DEGs were significantly involved in functions related to photosynthesis and valine, leucine, and isoleucine degradation. Differential metabolites were mainly associated with arginine and proline metabolism (1,3‐diaminopropane; 4‐aminobutyric acid; and N‐(omega)‐hydroxyarginine) and glycerophospholipid metabolism (lysoPC(16:0), phosphorylcholine, and triethanolamine). Our study identified differential genes and metabolites that were associated with the response of tobacco leaves to propamocarb hydrochloride. Propamocarb hydrochloride could influence the photosynthesis, amino acid metabolism, and glycerophospholipid metabolism of tobacco leaves.
Investigation of the applicability of TiO2, BiVO4, and WO3 nanomaterials for advanced photocatalytic membranes used for oil‐in‐water emulsion separation
Authors: Nascimben Santos Erika , Ágoston Áron , Kertész Szabolcs , Hodúr Cecilia , László Zsuzsanna , Pap Zsolt , Kása Zsolt , Alapi Tünde , Krishnan S.A. Gokula , Arthanareeswaran Gangasalam , Hernadi Klara , Veréb Gábor 
Published: July 2020

AbstractIn the present study, a commercial TiO2, several BiVO4 photocatalysts, a WO3 nanomaterial, and their composites were used to prepare photocatalytic polyvinylidene fluoride (PVDF) ultrafilter membranes. Their photocatalytic activities and the effects of coatings on the filtration of oil‐in‐water emulsion (crude oil; coil = 100 mg L−1) were investigated. Fluxes, filtration resistances, purification efficiencies, and fouling resistance abilities—like flux decay ratios (FDRs) and flux recovery ratios (FRRs)—were compared. The solar light‐induced photocatalytic decomposition of the foulants was also investigated. WO3 was used as a composite component to suppress the electron–hole recombination with the goal of achieving higher photocatalytic activity, but the presence of WO3 was not beneficial concerning the filtration properties. However, the application of TiO2, one of the investigated BiVO4 photocatalysts, and their composites was also beneficial. In the case of the neat membrane, only 87 L m−2 h−1 flux was measured, whereas with the most beneficial BiVO4 coating, 464 L m−2 h−1 flux was achieved. Pure BiVO4 coating was more beneficial in terms of filtration properties, whereas pure TiO2 coating proved to be more beneficial concerning the photocatalytic regeneration of the membrane. The TiO2(80%)/BiVO4(20%) composite was estimated to be the most beneficial combination taking into account both the aspects of photocatalytic activity and filtration properties.
Optimization of sulfonated polyethyleneimine zwitterionic coating mediated by polydopamine for poly(vinyl chloride) antifouling
Authors: Xu Wei , Li Shuangyang , Ye Zhanpeng , Zhang Jianhua , Deng Liandong , Dong Anjie 
Published: July 2020

AbstractAlthough poly(vinyl chloride) (PVC) has been widely used as blood‐contacting materials in extracorporeal circuits and indwelling medical devices, its hydrophobicity also is a limitation due to the adsorption of plasma proteins and the immediately followed thrombosis cascade and bacterial infections. Herein, we developed a mild and simple strategy for improving the hydrophilicity and antifouling properties of the surface via mussel‐inspired chemistry. Different amounts of 1,3‐Propanesultone (1,3‐PS) were attached onto the polyethyleneimine (PEI), so as to modify it into the zwitterion, called PESX. Two layer‐by‐layer approaches about PESX grafting on PVC substrates were designed. One strategy was by coating PESX after coating polydopamine (PDA) on PVC surface, obtaining PDA‐PESX coatings. The other was by grafting PESX after co‐deposition treatment of PDA and PESX with appropriate feeding ratio on PVC, obtaining PDA/PESX‐PESX coatings. The study results indicated that the PDA/PES0.5‐PES0.5 coatings with optimized PEI molecular weight and sulfonation degree, presented about 2.5–3 times reduction in BSA adsorption (0.77 μg/cm2) compared with PDA/PES0.5 (1.93 μg/cm2) and PDA‐PES0.5 (2.26 μg/cm2), and kept long time antifouling stability. Moreover, the more excellent antifouling performance of PDA/PES0.5‐PES0.5 was also seen on fibrinogen (Fg), γ‐globulin (γ‐GL), and the mixture of these proteins. Meanwhile, PDA/PES0.5‐PES0.5 could prevent the adhesion of blood components and bacteria on the surface as well as maintain excellent hemocompatibility and cytocompatibility. We had hopes that our simple and mild strategy will find practical application in surface engineering of clinical use in blood‐contacting medical devices.
Poly(hydroxamic acid) ligand from palm‐based waste materials for removal of heavy metals from electroplating wastewater
Authors: Rahman Md Lutfor , Wong Zhi Jian , Sarjadi Mohd Sani , Abdullah Mohd Harun , Heffernan Maria A. , Sarkar Md Shaheen , O'Reilly Emmet 
Published: July 2020

AbstractHeavy metals pollutants are nonbiodegradable and their bioaccumulation results in detrimental environmental consequences. Therefore, it is important to effectively remove toxic heavy metal waste from industrial sewage. Thus, the main goal of this research is to synthesize an ideal cellulose‐based adsorbent from palm‐based waste materials (agro waste) in order to be utilized in real‐life practical applications with low cost as such removing common toxic heavy metals from industrial effluents. A poly(methyl acrylate) grafted palm cellulose was synthesized via a free‐radical initiation process, followed by an oximation reaction to yield poly(hydroxamic acid) ligands. The adsorption capacity (qe) of poly(hydroxamic acid) ligands for metal ions such as copper (Cu2+), iron (Fe3+), and lead (Pb2+) were 325, 220, and 300 mg g−1, respectively at pH 6. In addition, the X‐ray photoelectron spectrometry results are to be proved the binding of metal ions, for instance, Cu(II) ions showed typically significant BEs of 932.7 and 952.0 eV corresponding to the Cu2p3/2 and Cu2p1/2 species. The heavy metal ions adsorption followed a pseudo‐first‐order kinetic model pathway. The adsorption capacity (qm) is also derived from the Langmuir isotherm linear plot, which does not showed good correction coefficients. However, the results were correlated to the Freundlich isotherm model, where the R2 value showed significance (>0.98), indicating that multiple layer adsorption occurs on the synthesized ligand. The synthesized polymeric ligand is an excellent adsorbent for the removal of heavy metals from the industrial wastewater. In addition, the metal analysis results showed that about 98% removal of copper and iron ions from electroplating wastewater including lead, nickel, and chromium can be removed up to 85–97%.
An Efficient RuTe2/Graphene Catalyst for Electrochemical Hydrogen Evolution Reaction in Acid Electrolyte
Authors: Gu Xiaocong , Yang Xudong , Feng Ligang 
Published: July 2020

AbstractDeveloping efficient powder catalysts for hydrogen evolution reaction (HER) in the acidic electrolyte is significant for hydrogen generation in the proton exchange membrane (PEM) water electrolysis technique. Herein, we demonstrated an efficient catalyst for HER in the acid media based on the graphene supported ruthenium telluride nanoparticles (RuTe2/Gr). The catalysts were easily fabricated by a facile microwave irradiation/thermal annealing approach, and orthorhombic RuTe2 crystals were found anchored over the graphene surface. The defective structure was demonstrated in the aberration‐corrected transmission electron microscopy images for RuTe2 crystals and graphene support. This catalyst required an overpotential of 72 mV to drive 10 mA cm−2 for HER when loading on the inert glass carbon electrode; Excellent catalytic stability in acidic media was also observed to offer 10 mA cm−2 for 10 hours. The Volmer‐Tafel mechanism was indicated on RuTe2/Gr catalyst by Tafel slope of 33 mV dec−1, similar to that of Pt/C catalysts. The high catalytic performance of RuTe2/Gr could be attributed to its high dispersion on the graphene surface, high electrical conductivity and low charge transfer resistance. This powder catalyst has potential application in the PEM water electrolysis technique because of its low cost and high stability.
Advances in Total Synthesis of Some 2,3,5‐Trisubstituted Tetrahydrofuran Natural Products
Authors: Fernandes Rodney A. , Pathare Ramdas S. , Gorve Dnyaneshwar A. 
Published: July 2020

Abstract2,3,5‐Trisubstituted tetrahydrofuran moiety is ubiquitous in natural products. These have served as appealing candidates for total synthesis due to their varied bio‐ and pharmaceutical activities. This tutorial review delineates the ingenious efforts by many researchers in the total synthesis of selected natural products based on a common 2,3,5‐trisubstituted tetrahydrofuran core structure. Many of the syntheses display nuanced interplay between new methods and the ingenuity of planned strategies achieved through catalysis or cascade chemistry. In some cases, the chiron approach has come quite handy, wherein the structural features and the stereochemistry in select molecules could map well with naturally available starting materials. This compilation also aims to enhance the diversity space based on these natural products and further interest in sustainable total synthesis.
Luminescence of the near‐ultraviolet blue‐emitting Ba9Al2Si6O24:Ce3+ phosphor
Authors: Teng Yongfu 
Published: July 2020

AbstractA near‐ultraviolet (NUV) blue‐emitting phosphor Ba9Al2Si6O24:Ce3+ (BAS:Ce3+) was synthesized using a high‐temperature solid‐state reaction. BAS:Ce3+ had an excitation band peak at about 328 nm and showed a blue emission band. The NUV‐blue emission band had a peak at about 386 nm with a band width of about 60 nm, attributed to the 5d–4f transition of Ce3+. Fluorescent decay showed an exponential model with a lifetime of 27.2 nsec. At 150°C, the luminescence intensity decreased to 68.7% compared with the intensity at room temperature.
The cultural consensus of sustainability‐driven innovation: Strategies for success
Authors: Van Holt Tracy , Statler Matt , Atz Ulrich , Whelan Tensie , van Loggerenberg Mara , Cebulla James 
Published: July 2020

AbstractAlthough sustainability may have previously appeared to business leaders primarily as an additional cost, today there are many signs of a change where sustainability appears to business leaders as a source or driver of value instead. Prior research shows that solving sustainability challenges should lead to innovations, yet we do not see widespread changes across companies. One reason may be that sustainability professionals do not share the same knowledge about the drivers and benefits of innovations that emerge when people solve sustainability challenges. To study this, we ran a cultural consensus analysis with sustainability professionals to test whether those with more sustainability expertise—that is, those with longer work experience in sustainability or to those that worked in companies where sustainability was embedded into core business operations—had different perspectives than those with less expertise. We found an overwhelming agreement among professionals regardless of expertise. We then followed up and conducted interviews with expert sustainability professionals to understand more about the business practices that drive sustainability‐driven innovation in their organizations.
Does financial development stimulate environmental sustainability? Evidence from a panel study of 115 countries
Authors: Uddin Mirza Md Moyen 
Published: July 2020

AbstractThis paper investigates the moderation effect of financial development (FD) on the environmental Kuznets curve (EKC). Using comprehensive panel data of 115 countries spanning the 1990–2016 period and dividing the countries into different income groups, the researcher found systematic differences in the relationship between significant indicators of environmental degradation and economic growth. More specifically, the interaction effect of FD on the relationship between gross domestic product (GDP) growth and CO2 emissions are positive; nevertheless, the interaction effect of FD on the relationship between GDP squared and CO2 emissions become negative for all income groups and therefore supports the EKC. Moreover, the interaction effect of FD is negative on the relationship of GDP with both CH4 and PM2.5 emissions in the middle‐income groups, whereas the interaction effect of FD on the relationship between GDP squared and PM2.5 emissions are negative for the high‐income group. Our results suggest that FD can reduce environmental degradation without adversely impacting on growth.
TOX correlates with prognosis, immune infiltration, and T cells exhaustion in lung adenocarcinoma
Authors: Guo Longbin , Li Xuanzi , Liu Rongping , Chen Yulei , Ren Chen , Du Shasha 
Published: July 2020

AbstractBackgroundThymocyte selection‐associated high mobility group box (TOX) plays a crucial role on the development of innate immunity and tumor microenvironment. This study aims to explore the prognostic potential of TOX and comprehensively analyze the correlations between TOX, immune infiltration, and T cells function in diverse cancers particularly lung adenocarcinoma (LUAD).MethodsTIMER was used to analyze TOX expression in different cancers. Potential prognostic value of TOX was evaluated by the PrognoScan, Kaplan‐Meier Plotter, and GEPIA2. The relationships between TOX, immune infiltration, and related gene marker sets were analyzed by TIMER and GEPIA2. Single‐cell RNA‐seq for T cells in LUAD was analyzed to further investigate the correlations between TOX expression and different T cells populations.ResultsTOX downregulates in most of the cancer types and correlates with poor prognosis in LUAD. TOX shows significant impacts on survival of LUAD with early stage, ever‐smoking, or low‐TMB status. Increased TOX expression positively correlates with high immune infiltration levels in most of the immune cells and functional T cells including exhausted T cells. Moreover, multiple key genes of exhausted T cells comprising PD‐1, TIM‐3, TIGHT, and CXCL13 have remarkable interaction with TOX. Specifically, TOX is observed with high enrichment in exhausted CD4+ and CD8+ T cells populations in single‐cell RNA‐seq analysis for LUAD.ConclusionTOX is a prognosis‐related biomarker for multiple cancer types especially LUAD. Increased TOX expression significantly increase immune infiltration levels in most of the immune cells comprising CD8+ T cells, CD4+ T cells, mast cells, and functional T cells. Moreover, we verified that TOX highly correlates with exhausted T cells and is probable a critical regulator promoted T cells exhaustion in LUAD. Detection of TOX expression could help to predict prognosis and regulating TOX expression in exhausted T cells may offer a novel strategy in maximizing immunotherapy efficacy for LUAD.
Maturity Onset Diabetes of the Young and Generalized Stage III Grade C Periodontitis: A Case Report
Authors: Chew Ren Jie Jacob , Chee Hoe Kit 
Published: July 2020

IntroductionMaturity onset diabetes of the young (MODY) is a rare form of diabetes mellitus resulting from single nucleotide polymorphisms. There is a lack of evidence describing their periodontal condition and the management of these patients. The objective of this case report is to present the 6‐month outcomes following non‐surgical periodontal treatment of a patient diagnosed with MODY 5, the Renal Cyst and Diabetes Syndrome.Case PresentationThis case report describes the periodontal presentation and non‐surgical management of a 21‐year‐old patient, diagnosed with hyperglycemia (HbA1c >14%) and stage 4 chronic kidney disease. She presented with generalized severe chronic periodontitis and multiple periodontal abscesses. She was treated with quadrant debridement with adjunctive systemic amoxicillin and metronidazole and 0.2% chlorhexidine mouth rinse. Significant improvement was observed after treatment, remaining stable 6‐month post‐treatment, with only two sites with probing depths ≥5 mm. This was consistent with a reduction of the periodontal inflamed surface area from 3165 to 500 mm2. HbA1c was also reduced to 8.7% 6 months after treatment.ConclusionsMODY patients presenting with periodontitis can be successfully treated non‐surgically, concurrent with diabetic management.
Clinical Decision Making for Primary Peri‐Implantitis Prevention: Practical Applications
Authors: Geisinger Maria L. , Calvert Grosso Katherine , Kaur Maninder , Abou‐Arraj Ramzi V. , Basma Hussein , Ogdon Dorothy , Geurs Nicolaas C. 
Published: July 2020

Focused Clinical QuestionWhen planning dental implant therapy, what risk‐reduction strategies allow practitioners to select patients, sites, and restorative plans that decrease the incidence of peri‐implant disease?SummaryWith a marked increase in the number of patients receiving dental implants to treat partial or complete edentulism, it follows that the prevalence of peri‐implant mucositis and peri‐implantitis have increased. Risks associated with implant therapies may vary based upon underlying local, environmental, surgical, patient, prosthetic, and fixture‐related factors. Furthermore, an emphasis on preventative measures and maintenance should be undertaken to avoid development and progression of peri‐implant diseases. Thorough risk assessment, proper treatment planning, and early diagnosis and intervention are critical in the absence of definitive data of long‐term success of treatments for peri‐implant condition. Given the difficulty in intervention once peri‐implantitis is established, identification of risk factors and development of treatment plans to address those factors before dental implant therapy is critical to the long‐term health and success of dental implants.ConclusionsA patient‐centered, evidence based approach to dental implant treatment planning to reduce the risk for peri‐implantitis should be undertaken. Systematic diagnosis of disease state(s) and evaluation of the etiologic and modifying risk factors for peri‐implant diseases can yield more optimal outcomes to reduce peri‐implantitis rates.
A Bimane‐Based Peptide Staple for Combined Helical Induction and Fluorescent Imaging
Authors: Horsfall Aimee J. , Dunning Kylie R. , Keeling Kelly L. , Scanlon Denis B. , Wegener Kate L. , Abell Andrew D. 
Published: July 2020

AbstractThe thiol‐selective fluorescent imaging agent, dibromobimane, has been repurposed to crosslink cysteine‐ and homocysteine‐containing peptides, with the resulting bimane linker acting as both a structural constraint and a fluorescent tag. Macrocyclisation was conducted on nine short peptides containing two cysteines and/or homocysteines, both on‐resin and in buffered aqueous solution, to give macrocycles ranging in size from 16 (i,i+2) to 31 (i,i+7) atoms. The structures were defined by CD, NMR structure calculations by using Xplor‐NIH, NMR secondary shift and JHαNH analyses to reveal helical structure in the i,i+4 (1, 2), and i,i+3 (5) constrained peptides. Cellular‐uptake studies were conducted with three of the macrocycles. Subsequent confocal imaging revealed punctate fluorescence within the cytosol indicative of peptides trapped in endocytic vesicles. These studies demonstrate that dibromobimane is an effective tool for defining secondary structure within short peptides, whilst simultaneously introducing a fluorescent tag suitable for common cell‐based experiments.
Modified Galacto‐ or Fuco‐Clusters Exploiting the Siderophore Pathway to Inhibit the LecA‐ or LecB‐Associated Virulence of Pseudomonas aeruginosa
Authors: Madaoui Mimouna , Vidal Olivier , Meyer Albert , Noël Mathieu , Lacroix Jean‐Marie , Vasseur Jean‐Jacques , Marra Alberto , Morvan François 
Published: July 2020

AbstractGalacto‐ and fuco‐clusters conjugated with one to three catechol or hydroxamate motifs were synthesised to target LecA and LecB lectins of Pseudomonas aeruginosa (PA) localised in the outer membrane and inside the bacterium. The resulting glycocluster–pseudosiderophore conjugates were evaluated as Trojan horses to cross the outer membrane of PA by iron transport. The data suggest that glycoclusters with catechol moieties are able to hijack the iron transport, whereas those with hydroxamates showed strong nonspecific interactions. Mono‐ and tricatechol galactoclusters (G1C and G3C) were evaluated as inhibitors of infection by PA in comparison with the free galactocluster (G0). All of them exhibited an inhibitory effect between 46 to 75 % at 100 μM, with a higher potency than G0. This result shows that LecA localised in the outer membrane of PA is involved in the infection mechanism.
Spontaneous improvement of sarcoidosis mimicking a vertebral metastatic lesion: It's indeed possible!
Authors: Rahmouni Safa , Maatallah Kaouther , Ferjani Hanene , Riahi Hend , Manamani Lamia , Kaffel Dhia , Hamdi Wafa 
Published: July 2020

AbstractThe diagnosis of vertebral sarcoidosis can be challenging. Besides, there is no consensus for the treatment of these lesions. Exceptionally, lesions may show spontaneous regression. To our knowledge, there are only two case reports of spontaneous resolution of vertebral sarcoidosis documented by follow‐up MRI. Herein, we present a third case.
Methane Combustion Over Ni/CexZr1–xO2 Catalysts: Impact of Ceria/Zirconia Ratio
Authors: Chen Junjie , Carlson Benjamin D. , Toops Todd J. , Li Zhenglong , Lance Michael J. , Karakalos Stavros G. , Choi Jae‐Soon , Kyriakidou Eleni A. 
Published: July 2020

AbstractA series of CexZr1–xO2 (x=1, 0.83, 0.17, 0) supports and 2 wt.% Ni/CexZr1–xO2 catalysts were synthesized and evaluated for CH4 oxidation. The CexZr1–xO2 supports showed moderate activity (T50=519‐638 °C) with CO by‐product formation. Nickel incorporation onto CexZr1–xO2 lowered the T50 to 438–477 °C and eliminated the formation of CO. The results indicated that moderate Zr doping improved the support oxygen storage capacity (OSC) and reducibility of the catalyst at low temperatures (H2‐TPR) leading to an enhanced CH4 combustion turnover frequency: Ni/ZrO2<Ni/Ce0.17Zr0.83O2<Ni/CeO2<Ni/Ce0.83Zr0.17O2. The apparent activation energies of Ni/CexZr1–xO2 catalysts (87‐92 kJ/mol) were much lower than the ones of CexZr1–xO2 supports and Ni/quartz sand (111‐120 kJ/mol) indicating that CH4 oxidation is facilitated when Ni is deposited on CexZr1–xO2. Moreover, stability tests with H2O and CO2 showed that Zr doping can improve the catalyst stability, while H2O had a stronger reversible inhibition effect than CO2 for CH4 combustion.