bluuebunny/crossref_metadata_2025_split huggingface dataset:
Navigating motherhood: biological and landscape factors affecting postpartum movement in white-tailed deer
Authors: Holland Angela M. , Haus Jacob M. , Dion Justin R. , Rogerson Joseph E. , Bowman Jacob L. 
Published: December 2024

Abstract
Background
Population growth and management in cervid species is dependent on reproductive ecology and factors influencing juvenile survival. Aspects of the female’s movement behavior likely affect juvenile survival and movement patterns of pregnant and lactating females differ from non-pregnant or non-lactating females. Explanations for these differing movement patterns include change in nutritional demands for the female, isolation during parturition, and predator avoidance. White-tailed deer (Odocoileus virginianus) are an important managed cervid and a better understanding of their reproductive ecology, including the relationships between resources, movement, and juvenile survival, can better inform management.

Methods
Our objective was to determine if biological factors, such as female age, fawn age, number of fawns, as well as characteristics of prepartum range affected the female’s postpartum daily movement or overlap of space used pre- and postpartum in Sussex County, Delaware, USA (2,420 km2). We collected GPS locations 2 weeks pre- and postpartum on 22 individual females from 2016 to 2017. In total, we recorded data from 263 days of postpartum movement for an average of 12 days/individual. We used a hierarchical modeling process to test biological factors and prepartum home range characteristics on two aspects of postpartum movement behavior, mean hourly displacements and daily use of prepartum home range.

Results
Mean hourly displacement decreased with increased female age and increased with number of known fawns alive and the female’s home range size prior to parturition. We found that as fawns aged the doe increased use of the prepartum home range.

Conclusions
Our results indicate that younger females are moving more than older females during lactation potentially to access higher quality habitat. This increased movement increases nutritional demand and may play a role in fawn survival. Females are more likely to use more of their prepartum home range as fawns age, a finding congruent with previous research. This differentiation in metric response (movement rate vs. space use) emphasizes the complexities of movement ecology and the importance of considering multiple dependent variables for complex behavior.
PtrA, Piz-t, and a novel minor-effect QTL (qBR12_3.3–4.4) collectively contribute to the durable blast-resistance of rice cultivar Tainung 84
Authors: Wang Sheng-Shan , Chang Wei-Bin , Hsieh Ming-Chien , Chen Szu-Yu , Liao Dah-Jing , Liao Ching-Ying , Shen Wei-Chiang , Chen Hong-Hua , Chen Chieh-Yi , Chen Yi-Chia , Lin Yueh-Lin , Tung Chih-Wei , Chen Ruey-Shyang , Chung Chia-Lin 
Published: December 2024

Abstract
Background
Rice blast caused by Pyricularia oryzae is a major threat to rice production worldwide. Tainung 84 (TNG84) is an elite japonica rice cultivar developed through the traditional pedigree method. It has maintained superior blast resistance since its release in 2010. This study aimed to investigate the genetic factors underlying the durable resistance of TNG84 in Taiwan.

Results
Quantitative trait locus (QTL) mapping was conducted using 122 F2 individuals and F2:3 families derived from the cross of TNG84 and a susceptible japonica cultivar Tainan 11 (TN11). Using 733 single nucleotide polymorphisms (SNPs) obtained through genotyping-by-sequencing and three P. oryzae isolates (D41-2, 12CY-MS1-2, and 12YL-TT4-1) belonging to different physiological races and Pot2 lineages, a major QTL was identified in the region of 52–54 cM (9.54–15.16 Mb) on chromosome 12. Fine-mapping using 21 F5:6 recombinants delimited the QTL to a 140.4-kb region (10.78 to 10.93 Mb) containing the known resistance gene Ptr. Sequencing analysis indicated that TNG84 carries the resistant PtrA allele and TN11 carries the susceptible PtrD allele. Investigation of the Ptr haplotypes in 41 local japonica rice cultivars revealed that eight PtrA-containing cultivars (19.5%) consistently exhibited good field resistance in Taiwan from 2008 to 2024. Subsequently, a few F5:6 lines (P026, P044, P092, and P167) lacking the resistant Ptr allele were observed to exhibit a resistant phenotype against P. oryzae 12YL-TT4-1-lab. Trait-marker association analyses using eight F6:7 homozygous recombinants, 378 BC1F2 from P044 backcrossed to TN11, and 180 BC1F2 from P092 backcrossed to TN11, identified Piz-t on chromosome 6 and a new QTL located between 3.3 Mb and 4.4 Mb on chromosome 12 (designated as qBR12_3.3–4.4). Analysis of 12 selected BC1F2:3 lines derived from P044 demonstrated that in the absence of Ptr and Piz-t, qBR12_3.3–4.4 alone reduced the disease severity index from approximately 6.3 to 3.9.

Conclusions
PtrA is likely the primary gene responsible for the broad-spectrum and durable resistance of TNG84. Piz-t confers narrow-spectrum resistance, while qBR12_3.3–4.4 contributes partial resistance. The discovery of qBR12_3.3–4.4 has provided a new source of blast resistance, and the markers developed in this study can be utilized in future breeding programs.
A systematic review of deep learning applications in database query execution
Authors: Milicevic Bogdan , Babovic Zoran 
Published: December 2024

AbstractModern database management systems (DBMS), primarily designed as general-purpose systems, face the challenging task of efficiently handling data from diverse sources for both analytical services and online transactional processing (OLTP). The volume of data has grown significantly, with distributions ranging from linear to highly skewed, sometimes involving very slow changes or rapid, intensive updates. Recent research in this field has been significantly influenced by advances in machine learning (ML), particularly deep learning (DL), and these developments have led to the application of various ML algorithms to enhance the efficiency of different parts of the query execution engine. While previous research studies were mostly focused on identifying drawbacks to individual components, such as the query optimizer, there is a notable lack of studies examining the applicability and effectiveness of various machine learning approaches across multiple aspects of the query execution engine. This article aims to provide a systematic review of approaches that apply deep learning models at various levels within the query execution engine. We categorize these approaches into three groups based on how such models are applied: improving performance of index structures and consequently data manipulation algorithms, query optimization tasks, and externally controlling query optimizers through parameter tuning. Furthermore, we discuss the key challenges associated with implementing deep learning algorithms in DBMS.
Respiratory physiotherapy for critically ill children: concern regarding a recommendation
Authors: Shime Nobuaki 
Published: December 2024

AbstractThe guideline entitled “Japanese Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients 2023” was published by the Japanese Society of Intensive Care Medicine in 2023. However, there is an issue with the clinical question and recommendation for respiratory physiotherapy in mechanically ventilated children. Although the evidence was based on two randomized controlled trials regarding prone positioning, the recommendation may have risk of misunderstanding as a recommendation for all respiratory physiotherapy. There are abundant evidence-based recommendations against chest physiotherapy for infants with bronchiolitis with no benefit and possible adverse events. Revising the recommendation for respiratory physiotherapy in critically ill, mechanically ventilated children should be considered.
Do personal recommendations need to be personalized? Investigating the relationships between student differences and educational recommendations
Authors: Dai Yiling , Hoppe Heinz Ulrich , Flanagan Brendan , Takami Kyosuke , Ogata Hiroaki 
Published: December 2024

AbstractEducational recommender systems have been supporting personalized learning in various ways. However, less discussion is conducted about whether and how to personalize the strategies to generate recommendations based on student differences. In this study, we aim at investigating how students judge recommendations based on different strategies, and how these judgments relate to student characteristics. We conducted a large-scale questionnaire survey to measure students’ Big-Five personality traits, confidence in the subjects, and their judgments on six types of recommendations. The answers collected from 735 high school students in Japan indicate that students had different judgments across different recommendation strategies, but similarly for English and mathematics. Furthermore, the correlations between student characteristics and their judgments on recommendations were stronger if the subject to learn was inconsistent with the subject they preferred. The results provide insights on how to design educational recommendations that not only cater to students’ traits, but also help foster and enhance their traits for better learning.
Spatial and temporal variations of the 3-year earthquake swarm activities leading up to the M7.6 Noto Peninsula earthquake and interpretations of their activities
Authors: Kumazawa Takao , Ogata Yosihiko 
Published: December 2024

AbstractThe seismic swarm activity that began and expanded in four separate regions in the northern Noto Peninsula at the end of 2020 was followed by the M6.5 earthquake in May 2023, which cascaded into the M7.6 earthquake on New Year’s Day 2024. To this series of earthquake events, we estimate temporal changes in the background intensity of the nonstationary ETAS model by inversion for each region. We then interpret how this series of earthquakes was driven by subsurface fluid motion and slow slip at each stage, based on the correspondence between the background seismicity changes and the temporal changes in oblique distance and elevation differences between nearby GNSS stations, as well as the spatiotemporal earthquake patterns.
Graphical Abstract
Improving the prediction of patient survival with the aid of residual convolutional neural network (ResNet) in colorectal cancer with unresectable liver metastases treated with bevacizumab-based chemotherapy
Authors: Chiu Sung-Hua , Li Hsiao-Chi , Chang Wei-Chou , Wu Chao-Cheng , Lin Hsuan-Hwai , Lo Cheng-Hsiang , Chang Ping-Ying 
Published: December 2024

Abstract
Background
To verify overall survival predictions made with residual convolutional neural network-determined morphological response (ResNet-MR) in patients with unresectable synchronous liver-only metastatic colorectal cancer (mCRC) treated with bevacizumab-based chemotherapy (BBC).

Methods
A retrospective review of liver-only mCRC patients treated with BBC from December 2011 to Apr 2021 was performed. Patients who had metachronous liver metastases or received locoregional treatment before the initiation of BBC were excluded. The percentage of downstaging to curative treatment and overall survival (OS) were recorded. Two abdominal radiologists evaluated portal venous phase CT images based on the morphological criteria and divided the images into Groups 1, 2, and 3. These images were used to establish the radiologists-determined morphological response (RD-MR), which classified patients into responders and non-responders based on the morphological change 3 months after the initiation of BBC. Then, the Group 1 and 3 images classified by the radiologists were input into ResNet as the training dataset. The trained ResNet then redivided the Group 2 images into Groups 1, 2 and 3. The ResNet-MR was determined on the basis of these redivided images and the initial Group 1 and 3 images classified by the radiologists.

Results
Eighty-four patients were included in this study (53 males and 31 females, with a median age of 60.0 years). The follow-up time ranged from 10 to 86 months. A total of 407 CT images were input into ResNet as the training dataset. Both RD-MR and ResNet-MR correlated with OS (p value = 0.0167 and 0.0225, respectively). Regarding discriminatory ability for mortality, ResNet-MR had higher area under curve than RD-MR at both 1 year and 2 years and showed a significant difference in discriminatory ability (p-value = 0.0321) at 2 years. RD-MR classified 28 patients (33.3%) as responders, and ResNet-MR classified an additional 16 patients (19.0%) as responders; these 16 patients had longer OS than the remaining non-responders in the RD-MR group (27.49 versus 21.20 months, p value = 0.043) and had a higher percentage of downstaging (37.5% versus 17.5%, p value = 0.1610).

Conclusions
In CRC patients with liver metastases treated with BBC, prediction of survival can be improved with the aid of ResNet, enabling optimized individualized treatment.
Development and validation of intravoxel incoherent motion diffusion weighted imaging-based model for preoperative distinguishing nuclear grade and survival of clear cell renal cell carcinoma complicated with venous tumor thrombus
Authors: Zhao Jian , Xu Honghao , Fu Yonggui , Ding Xiaohui , Wang Meifeng , Peng Cheng , Kang Huanhuan , Guo Huiping , Bai Xu , Zhou Shaopeng , Liu Kan , Li Lin , Zhang Xu , Ma Xin , Wang Xinjiang , Wang Haiyi 
Published: December 2024

Abstract
Objective
To assess the utility of multiparametric MRI and clinical indicators in distinguishing nuclear grade and survival of clear cell renal cell carcinoma (ccRCC) complicated with venous tumor thrombus (VTT).

Materials and methods
This study included 105 and 27 patients in the training and test sets, respectively. Preoperative MRI, including intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI), was performed. Renal lesions were evaluated for IVIM-DWI metrics and conventional MRI features. All the patients had postoperative histologically proven ccRCC and VTT. An expert uropathologist reviewed all specimens to confirm the nuclear grade of the World Health Organization/ International Society of Urological Pathology (WHO/ISUP) of the tumor. Univariate and multivariable logistic regression analyses were used to select the preoperative imaging features and clinical indicators. The predictive ability of the logistic regression model was assessed using receiver operating characteristic (ROC) analysis. Survival curves were plotted using the Kaplan–Meier method.

Results
High WHO/ISUP nuclear grade was confirmed in 69 of 105 patients (65.7%) in the training set and 19 of 27 patients (70.4%) in the test set, respectively (P = 0.647). Dp_ROI_Low, tumor size, serum albumin, platelet count, and lymphocyte count were independently related to high WHO/ISUP nuclear grade in the training set. The model identified high WHO/ISUP nuclear grade well, with an AUC of 0.817 (95% confidence interval [CI]: 0.735–0.899), a sensitivity of 70.0%, and a specificity of 77.8% in the training set. In the independent test set, the model demonstrated an AUC of 0.766 (95% CI, 0.567–0.966), a sensitivity of 79.0%, and a specificity of 75.0%. Kaplan–Meier analysis showed that the predicted high WHO/ISUP nuclear grade group had poorer progression-free survival than the low WHO/ISUP nuclear grade group in both the training and test sets (P = 0.001 and P = 0.021).

Conclusions
IVIM-DWI-derived parameters and clinical indicators can be used to differentiate nuclear grades and predict progression-free survival of ccRCC and VTT.
Minimally invasive balloon-assisted sinus floor elevation vs. conventional transcrestal procedure in terms of new bone formation in a split-mouth Goettingen minipig model
Authors: Kolk Andreas , Bauer Florian , Weitz Jochen , Stigler Robert , Walch Benjamin , Grill Florian , Boskov Marko 
Published: December 2024

Abstract
Purpose
Currently, maxillary sinus floor (SF) elevation is based on off-the-shelf allogeneic, xenogeneic or synthetic bone augmentation materials (BAM) that are implanted via an open lateral sinus wall approach (OSFE). However, this invasive method is associated with postoperative complications caused by an inadequate blood supply of the alveolar ridge. Balloon-assisted procedures are minimal invasive alternatives with lower complication rates. The aim was to evaluate local new bone (NB) formation in the SF following the application of a particulate BAM (Easy graft) via two different SF elevation techniques in a split mouth mini-pig sinus augmentation model.

Material and methods
Seven adult Goettingen minipigs were used for evaluation of a biphasic ceramic (PLGA/ß-TCP) BAM in the elevated SF region. Treatments were randomized to the contralateral sinus sites and included two procedures: OSFE (control group) versus minimally invasive SF elevation by a balloon-lift-control system (BLC) (treatment group). The animals were euthanized after 28 and 56 days for analysis of new bone (NB) formation.

Results
The biphasic synthetic BAM implanted via BLC increased more NB formation (5.2 ± 1.9 mm and 4.9 ± 1.6 mm vs. 2.6 ± 0.5 mm) and osseointegration of the particles (18.0 ± 6.0% and 25.1 ± 18.2% vs. 10.1 ± 8.0%, p < 0.05) compared to the control.

Conclusions
Implantation of a biphasic synthetic BAM enhanced NB formation in the mini-pig maxillary sinus at both time points and in both groups, although BLC resulted in a slightly better total NB formation compared to the control.

Graphical abstract
“Do good and talk about it”: informal representation and migrant-led civil society organizations’ mediation between low-wage labor migrants and state institutions in the GCC countries
Authors: Burmeister-Rudolph Mira 
Published: December 2024

AbstractLow-wage labor migrants experience major human and working rights abuses in the Gulf Cooperation Council countries despite national labor laws and signatures to various human rights conventions. On paper, India has established an institutional framework of transnational social protection for its officially estimated 5.5 million low-wage workers migrating to the Gulf Cooperation Council countries, e.g., financial emergency support, repatriation services, and walk-in centers. However, migrants in low-wage employment often cannot access substantive social rights in practice. Indian upper/middle-class migrant civil society groups mediate their access to Indian embassies’ services and the destination countries’ state institutions. The realization of social rights via informal, third-party representation stems from a representational disjuncture between low-wage labor migrants and the Indian state, which is rooted in their historical socioeconomic marginalization, limitations of the formal political system, and the constitutive role of informality in shaping and structuring citizen-state interactions in India. Through the lens of Piper and von Lieres’ (2015) concept of mediated citizenship and based on data from semi-structured interviews and participant observation of migrant support networks in the Gulf countries, this article examines why mediation takes place and how volunteers speak and take action for marginalized migrants in low-wage employment and consequences of mediation. It argues that migrant volunteer organizations and individuals are powerful stakeholders in the migration governance in the GCC region, as they possess leverage over who has (better) access to state institutions and the provision of social and human rights. Their status as intermediaries underlines the disaggregation of Indian citizenship along class and caste lines, which can be (mis)-used by mediators to pursue their interests, resulting in ambiguous effects. The article contributes to perspectives on migration governance in the GCC region, transnational social policies, and migrant volunteering.
Long-term evaluation of Elmelegy’s technique of local muscle transposition for the functional restoration of large upper or lower lip defects
Authors: Elmelegy Nader G. 
Published: December 2024

Abstract
Background
Although more than 200 techniques have been reported for the reconstruction of the upper and lower lip defects since 1000 BC, none of them is ideal.
Local flaps may result in extra skin incisions and in some cases, the surgeon may be confronted with the lack of sufficient tissues for the reconstruction of large defects.
Several techniques have been described for near-total lip reconstruction. The two major available techniques are local flap reconstruction (Bernard–von Burrow–Webster technique) and free micro-vascular tissue transfer.
In this study, we are going to evaluate the functional results of using local muscles transposition-assisted dermal fat flap and muco-buccal flap in the treatment of large upper or lower lip defects.

Materials and methods
This study was carried out on 128 patients, who presented to us with malignant tumors affecting the lips.

Results
Lip defect sizes ranged from 4 to 6 cm in diameter. No flap failure was seen and desirable function and accepted esthetic results were obtained. The flap survival was 100%, and healing was eventful in all cases. No cases of microstomia were reported.

Conclusion
The use of local muscle transposition-assisted dermal fat flap and muco-buccal flap technique, showed excellent results in regaining oral competence and lip mobility, and as much as possible, increased the aesthetic outcome.

Level of evidence
IV therapeutic study.
The relationship of macular vessel density and foveal avascular zone with pulse wave velocity and central blood pressure in healthy adults: Persian cohort study
Authors: Heidarzadeh Hamid Reza , Ebrahimi Miandehi Elaheh , Shoeibi Nasser , Ansari Astaneh Mohammad Reza , Hosseini Seyedeh Maryam , Abrishami Majid , Motamed Shariati Mehrdad , Eslami Saeid , Arjmand Parnian , Abrishami Mojtaba 
Published: December 2024

Abstract
Background
To evaluate the correlation of macular vessel density (VD) and foveal avascular zone (FAZ) parameters measured on optical coherence tomography angiography (OCTA) with systemic arterial stiffness using pulse wave velocity (PWV), pulse wave analysis, arterial age, and central blood pressure (CBP) measurements in healthy subjects.

Methods
In a comparative, cross-sectional, observational study, healthy adults who participated in the PERSIAN Cohort study at Mashhad University of Medical Sciences were included in this study. The study involved using a spectral domain OCTA device to obtain 3 × 3 and 6 × 6 mm scans of the macular superficial capillary plexus (SCP) VD, deep capillary plexus (DCP) VD, and FAZ vascular analysis. Additionally, we used the SphygmoCor XCEL System (AtCor, Itasca, IL) to analyze systemic vascular parameters like CBP and PWV.

Results
The study included 296 healthy participants with a mean age of 39.2 ± 6.7 years, and 152 subjects (51.3%) were female. Female participants were found to have higher DCP VD and FAZ area values. Age showed a negative correlation with SCP and DCP VDs. PWV showed a negative correlation with parafoveal DCP VDs, but no correlation was observed between macular VDs and aortic diastolic and systolic pressures.

Conclusion
In conclusion, age was found to have a negative impact on macular SCP and DCP VDs. In addition, higher arterial stiffness was found to correlate with a lower parafoveal DCP VD value. These findings suggest macular OCTA parameters may be used as early markers of systemic arterial disease.