bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dietary habits of High School Population in Mostar, Bosnia and Herzegovina
Authors: Coric Nevena , Juric Anita , Tambic Antonio , Vujevic Leonarda , Knezovic Zrinka 
Published: May 2020

Abstract
Background

Adolescence is a period of life when prevalence of overweight, obesity and chronic non-communicable diseases rise the fastest. This period of life is very important for adoption of healthy lifestyle habits. Those include regular physical activity and diet, which could prevent nutrient deficiencies and may limit harmful behaviors contributing to the epidemic of non-communicable diseases in adulthood. There are a small number of surveys on a large number of high school and student population about this topic in low-to middle income countries.
Methods

The aim of this study was to examine dietary habits and frequency of physical activity and presence of non-communicable diseases in immediate family. Survey was conducted in 6 secondary schools of city of Mostar through an anonymous questionnaire. The study involved 482 adolescents (279 boys and 203 girls) aged 17 and 18. For data entry and analysis SPSS (version 25) was used. Association between variables was determined using chi-square.
Results

Collected data showed low breakfast consumption by adolescents, low everyday consumption of vegetables, fruits, and dairy products. There is a high trend of daily consumption of meat, especially processed meat as also as relatively high consumption of soft drinks. In addition, data showed difference in physical activity of boys and girls.
Conclusion

There were significant deviations in dietary habits of participants compared with health needs recommended for adolescent population. Therefore, it is necessary to develop and organize better nutritional education for adolescents and involve wider community to implement public health programs in order to adopt a healthier lifestyle for adolescents.
A Patient perspective of Complementary and Integrative Medicine (CIM) for Migraine Treatment: A social media survey
Authors: Kuruvilla Deena E , Mehta Amit , Ravishankar Nidhi , Cowan Robert 
Published: May 2020

Abstract
OBJECTIVE: To survey persons with migraine who use social media about Complementary and Integrative Medicine (CIM) for the treatment of migraine.BACKGROUND: CIM encompasses medical treatments that are not part of ,but are used in concert with, mainstream medicine. Between 28–82% of people with migraine use non-drug approaches, and approximately 50% of people with migraine do not discuss non-drug treatments with their healthcare providers (HCPs) 9. it is important for providers to be conversant with CIM treatments and the available evidence-based data. To further this effort, the Complementary and Integrative Medicine Special Interest Section (CIMSIS) of the American Headache Society surveyed migraine patients directly through social media to identify CIM practices in which they engage.METHODS: In collaboration with the American Migraine foundation (AMF) and Yakkety Yak, a digital marketing agency, we posted a 17-question survey on the Move Against Migraine (MAM) Facebook group, which has 20,000 + members. The goals of the survey were to assess the attitudes toward CIM among this group, to identify which CIM modalities are being used and to determine what patients considered to be the most effective CIM modalities. While Yakkety Yak posted the survey link on the group page, the survey itself was hosted on Qualtrics, a confidential survey service. Qualtrics provides tools to configure survey properties and to customize privacy settings, so respondents cannot be tracked to an IP or email address, name or ticket number, which allows for anonymous responses. Our study was submitted for review to the IRB (institutional review board) and was exempted.RESULTS: 372 MAM members (approximately 2%) responded to the questionnaire, of which 335 reported using CIM; between 114–139 (34–42%) found CIM modalities to be at least mildly effective. Of note, 164 (49%) reported using cannabis derivatives or cannabinoids, specifically with, 64/164 (39%) reporting that cannabis was not effective for them.CONCLUSIONS: This study provides an initial investigation into the demographic and practice patterns of patients who use CIM. While it must this sampling may not reflect CIM use across all individuals with migraine, it does strongly suggest the need for better education on the role of, and evidence for, CIM among headache care providers, and the need to ask patients specifically about their use of and interest in CIM.
LncRNA IMFlnc1 promotes porcine intramuscular adipocyte differentiation by sponging miR-199a-5p to up-regulate CAV-1
Authors: Wang Jing , Chen Junfeng , Chen Mingyue , Hua Liushuai , Ren Qiaoling , Zhang Jiaqing , Cao Hai , Bai Xianxiao , Pan Chuanying , Xing Baosong 
Published: May 2020

Abstract
Background Local Chinese local pig breeds have better meat quality, such as thinner muscle fiber and higher intramuscular-fat (IMF) content. However, its molecular regulation mechanism has not been discussed in-depth. Studies indicated that long non coding RNAs (lncRNAs) participate in the regulation of muscle and fat development. The expressional differences of lncRNAs in the longissimus dorsi (LD) muscle were identified between Huainan pigs (local Chinese pigs, fat-type, HN) and Large White pigs (lean-type, LW) at 38, 58, and 78 days post conception (dpc).Results In total, 2131 novel lncRNAs were identified in 18 samples, and 291, 305, and 683 differentially expressed lncRNAs (DELs) were found between these two breeds at three stages, respectively. GO and KEGG analysis of the DEL co expressed mRNAs showed that muscle development and energy metabolism were more active at 58 dpc in HN, but at 78 dpc in LW pigs. Muscle cell differentiation and myofibril assembly might contribute to earlier myogenesis and primary-muscle-fiber assembly in HN, and cell proliferation, insulin, and the mitogen-activated protein kinase (MAPK) pathway might contribute to longer proliferation in LW pigs. The PI3K/Akt and cAMP pathways were associated with higher IMF deposition in HN. IMFlnc1 was selected for functional verification, and results indicated that it regulated the expressional level of caveolin-1 (CAV-1) as a competing endogenous RNA (ceRNA) for miR-199a-5p.Conclusion Our data contributed to understanding lncRNAs in porcine-muscle development and IMF deposition, and provided valuable information for improving pig-meat quality.
Geographic and Socioeconomic Disparities in Nutritional Status of Women in Pakistan: Secondary Analysis from Pakistan National Nutrition Survey
Authors: Sadiq Kamran , Mahmood Bushra , Kureishy Sumra , Ariff Shabina , Mustafa Ghulam , Khan Gul Nawaz , Umer Muhammad , Memon Zahid , Janjua Naveed , Soofi Sajid , Bhutta Zulfiqar A 
Published: May 2020

Abstract
Background: Pakistan is experiencing a rapid nutrition transition with a shift from underweight to overweight and obesity. This paper will examine the role of household socioeconomic position (SEP), community SEP and urbanicity on the nutritional status (underweight, overweight and obesity) of Pakistani women. Methods: We analysed data on 34,391 women aged ≥20 years enrolled in 2011 National Nutritional Survey of Pakistan (NNS). The NNS is a nationally representative survey employing a multistage stratified cluster sampling design. We assessed household SEP through a wealth index constructed using items from household possessions, utilities and housing conditions. We assessed the relationship of urbanicity, household and community SEP with categories of body mass index (BMI) using multinomial logistic regression where normal BMI (18.6-22.5 kg/m 2 ) was the reference category. Results: Overall, 15% of women were underweight (BMI<18.5 kg/m 2 ), 14% were pre-overweight (BMI 23.00-24.9 kg/m 2 ), 22% were overweight (BMI 25.0-29.99 kg/m 2 ) and 12% were obese (BMI≥30.0 kg/m 2 ). Households with higher SEP were associated with increased levels of overweight-1 (aOR: 2.91; 95%CI: 2.41-3.50), overweight-2 (aOR: 4.15; 95%CI: 3.31-5.19) and obesity (aOR: 6.20; 95%CI: 4.92-7.81) among women. Women were more likely to be obese in major urban (aOR: 2.34; 95%CI: 2.02-2.71) and urban (aOR: 1.84; 95%CI: 1.62-2.09) areas compared to rural areas. At the community level, communities in rural areas were more likely to have higher levels of underweight, while communities in urban areas were more likely to have higher levels of obesity. Furthermore, the likelihood of underweight and overweight women coexisting within the same community was low in major urban (r=0.67), urban (r=0.55) and rural (r=0.54) areas. Conclusions: In Pakistan, overweight and obesity among women is associated with urbanicity and household and community SEP. Women living in urban areas with high household and community SEP were associated with higher levels of overweight and obesity. Our findings suggest the importance of interventions targeting undernutrition in rural areas and overnutrition in urban areas.
Travelling and COVID-19: A Mathematical Model
Authors: Banerjee Sankha 
Published: May 2020

Abstract
A non-linear mathematical model is proposed to study the impacts of travelling in human-human transmission of COVID- 19.Two different regions are considered and transmission dynamics of COVID-19 dissemination in two regions caused by travelling from one region to other and infection during travel are discussed.Besides contacts between susceptible and infected population of a region off the travel,transmission of disease due to contacts during travel is also considered.The proposed model is analysed using stability theory of ordinary differential equation and feasibility of qualitative results ia checked through numerical simulations.From obtained results,it is shown that travelling and population dispersal can aggravate disease spreading in each region.It is also inferred that rate of travelling and rate of contacts during travel and off the travel can ease the disease to take endemic form and for high rates,it may become pandemic. Further numerical calculations are performed and critical limits of the major factors enhancing spreading of disease.It is revealed that when the rates goes higher than their corresponding critical limits,disease may not be controlled due to high infection.It is also imparted that when the rates are high, disease can only be controlled with high rate of quarantine.Also approximate time or stability is evaluated for maximum as well as minimum rates of key parameters.The results obtained by analyzing the model recommends that for early stability of endemic situation, key factors must be kept as minimum as possible within estimated limits and quarantining infected class to control the transmission of disease.
Computational studies on Gene Ontology for Molecular functions, Cellular component and Biological process of SARS-CoV-2 targeted proteins
Authors: Manikyam Hemanth kumar 
Published: May 2020

Abstract
World is facing pandemic COVID-19 caused by SARS-CoV-2.Researchers are working to identify potential cure and treatment for COVID-19. Many Repurposed drugs been proposed to treat the infection with good success rate in some cases. But still there is an urgency to discover potential cure and treatment. In order to discover potential cure we should understand the Gene Ontology of targeted proteins of SARS-CoV-2 for their Molecular functions, cellular component and Biological process. Spike glycoproteins, Main protease (Mpro), Papain like protease (PLpro) are three main proteins that aid viral host cell entry and its replication causing pathogenesis. Using MetaGO an algorithm an algorithm for predicting Gene Ontology (GO) of proteins the Molecular functions, Cellular component and Biological process of SARS-CoV-2 proteins studied. MetaGO analysis had predicted Spike protein gene ontology functions include host cell surface binding, receptor binding, host cell surface receptor binding, structural molecule activity, carbohydrate binding. Main Protease (Mpro) and Papain like protease (PLpro) gene ontology functions predicted hydrolase activity, RNA-directed RNA polymerase activity, ubiquitinyl hydrolase activity, Lys48-specific deubiquitinase activity, mRNA (nucleoside-2'-O-)-methyltransferase activity, mRNA (guanine-N7-)-methyltransferase activity, double-stranded RNA binding, 3'-5'-exoribonuclease activity, helicase activity, single-stranded RNA binding, cysteine-type endopeptidase activity, omega peptidase activity, zinc ion binding, thiol-dependent ubiquitinyl hydrolase activity, ATP binding, endonuclease activity among which PLpro had shown inhibition of ISG15 activity in additional. Inhibition of ISG15 indicates down regulation of interferon production particularly Interferon Type 1. PYCR1 (Pyrroline-5-carboxylate reductase 1) which protects the cells from mitochondrial damage due to oxidative stress shown to be inhibited by Spike protein hydrolase like activity and leading to cell death.PYCR1 can be a diagnostic tool to detect novel coronavirus infection. Viral proteins also use cellular Ubiquitinyl enzymes for its replication and survival in host cell. Thus through gene ontology studies we propose use of Interferon type 1 therapy against COVID-19 caused by SARS-CoV-2.
Applicability of urban streets as temporary open floodways
Authors: Skrede Thea Ingeborg , Muthanna Tone Merete , Alfredesen Knut 
Published: May 2020

Abstract
Climate change coupled with urbanization and its increasing impervious surfaces have caused major challenges for the water sector worldwide. In Norway, an ageing infrastructure with already insufficient drainage capacities results in large amounts of runoff during high-intensity rainfall events causing frequent floods in urban areas. Due to limited available space to handle the future projected increase in stormwater, there is a need to utilize already occupied space for stormwater management, such as roads and streets, during extreme events. Limited research has been done on the design and applicability of urban streets as temporarily flood ways diverting stormwater to the nearest recipient. This paper will study the benefits and limitations of adapting urban streets as safe flood ways to route stormwater by modelling an urban street as a floodway. Streets as floodways will require additional hydraulic performance criteria and safety criteria. Performance criteria are identified and evaluated, and a method is proposed for the evaluation of urban streets applicability as floodways. The method can be used to evaluate the applicability of multifunctional streets used as urban floodways and can be adapted by municipalities as a decision support tool for stormwater management.
Solar energy-based water treatment system applicable to the remote areas: Case of Indonesia
Authors: Wibowo Arsanto Ishadi , Chang Keh-Chin 
Published: May 2020

Abstract
Remote areas usually lack basic clean water services. Considering low population, poor geographical accessibility and lack of electricity, a small-scaled water treatment system capable of producing clean fresh water associated with solar thermal/photovoltaic applications, which is characterized with low capital cost, easy operation and less need of maintenance, is employed in the techno-economic study. Indonesia is one of the countries which owns considerable water resources in their territories but has moderate coverage in basic water services, and is chosen as a case for demonstration. The price of clean water from this system is profitable as compared to that of bottled water, which is an accessible safe water in these areas, but still much higher than that of municipal water.
This article has been made Open Access thanks to the generous support of a global network of libraries as part of the Knowledge Unlatched Select initiative.
A comparative study on rainfall runoff control indicators of green roof
Authors: Zhou Ke 
Published: May 2020

Abstract
The rainfall runoff reduction effect on green roofs was analyzed and tested by comparative rainfall runoff monitoring on impermeable roofs (sloping, plane). The evaluation index of rainfall runoff interception benefit (relative runoff reduction rate, rainfall control rate) on green roofs was studied. The results show that compared with sloping and level roofs, the change range of green roof runoff reduction rate relative to level and sloping roofs is 20.0–98.3% and 3.8–92.3%, and the mean value is 48.4% and 34.3% respectively. It is obvious that the green roof has better rainfall runoff reduction effect. It can be seen from the single rainfall control effect that the variation range of green roof rainfall runoff control rate is 36.0% to 99.0%, and the total rainfall control rate is 57.6%, which reflects that the green roof has the better rainfall control effect. Through comparative study, it can be concluded that the rainfall runoff control rate is more suitable for the design index of green roofs.
Świątynia pod wezwaniem Zesłania Ducha Świętego w Otwocku, jej wystrój, symbolika i treści teologiczne dekoracji
Authors: Kobielus Stanisław 
Published: May 2020

W powstaniu struktury architektonicznej budowli świątyni pod wezwaniem Zesłania Ducha Świętego w Otwocku miał udział zespół architektów. Udział w dyskusji nad programem dekoracji wzięli: ks. Stanisław Kobielus, ks. Henryk Herkt oraz artysta Andrzej Zaborowski. Budowę świątyni ukończono w 1987 r. zaś konsekracji dokonał 7 maja 1988 r. ks. biskup Marian Duś. Świątynia posiada bardzo bogaty program ideowy związany z symboliką figur geometrycznych i odwołujący się do tekstów Pisma Świętego, Ojców Kościoła, a także Katechizmu Kościoła Katolickiego. Na ścianie ołtarzowej przedstawiono scenę Zesłania Ducha Świętego, ponieważ parafia i świątynia noszą takie wezwanie. Jednak ideą przewodnią w dekoracji kościoła jest tematyka Niebiańskiej Jerozolimy, która do dziś w Kościele jest uznawana za alegoryczne miejsce ostatecznego szczęścia człowieka po śmierci.
The Pentecost church in Otwock. Symbolism and theological meaning of its decoration
A group of architects worked on the form of the building of the Pentecost church in Otwock. Rev. Stanisław Kobielus, Rev. Henryk Herkt and artist Andrzej Zaborowski discussed the decoration and detailing. The building was finished in 1987 and it was consecrated on the 7th May 1988 by Bishop Marian Duś. The complex ideological decoration of the church is related to the symbolism of geometric figures and refers back to the Scriptures, the writings of the Fathers of the Church and the Catechism of the Catholic Church. The altar centrepiece presents the Pentecost scene referring to the invocation of the church and its parish. However, the main theme in the decoration of the church is the representation of the New Jerusalem which until today is considered by the Church as an allegorical place of eternal happiness after death.
Anticancer Properties of Asian Water Monitor Lizard (Varanus salvator), Python (Malayopython reticulatus) and Tortoise (Cuora kamaroma amboinensis)
Authors: Jeyamogan Shareni , Khan Naveed A. , Sagathevan Kuppusamy , Siddiqui Ruqaiyyah 
Published: May 2020

Background:Cancer contributes to significant morbidity and mortality despite advances in treatment and supportive care. There is a need for the identification of effective anticancer agents. Reptiles such as tortoise, python, and water monitor lizards are exposed to heavy metals, tolerate high levels of radiation, feed on rotten/germ-infested feed, thrive in unsanitary habitat and yet have prolonged lifespans. Such species are rarely reported to develop cancer, suggesting the presence of anticancer molecules/mechanisms.Methods:Here, we tested effects from sera of Asian water monitor lizard (Varanus salvator), python (Malayopython reticulatus) and tortoise (Cuora kamaroma amboinensis) against cancer cells. Sera were collected and cytotoxicity assays were performed using prostate cancer cells (PC3), Henrietta Lacks cervical adenocarcinoma cells (HeLa) and human breast adenocarcinoma cells (MCF7), as well as human keratinized skin cells (Hacat), by measuring lactate dehydrogenase release as an indicator for cell death. Growth inhibition assays were performed to determine the effects on cancer cell proliferation. Liquid chromatography mass spectrometry was performed for molecular identification.Results:The findings revealed that reptilian sera, but not bovine serum, abolished viability of Hela, PC3 and MCF7 cells. Samples were subjected to liquid chromatography mass spectrometry, which detected 57 molecules from V. salvator, 81 molecules from Malayopython reticulatus and 33 molecules from C. kamaroma amboinensis and putatively identified 9 molecules from V. salvator, 20 molecules from Malayopython reticulatus and 9 molecules from C. kamaroma amboinensis when matched against METLIN database. Based on peptide amino acid composition, binary profile, dipeptide composition and pseudo-amino acid composition, 123 potential Anticancer Peptides (ACPs) were identified from 883 peptides from V. salvator, 306 potential ACPs from 1074 peptides from Malayopython reticulatus and 235 potential ACPs from 885 peptides from C. kamaroma amboinensis.Conclusion:To our knowledge, for the first time, we reported comprehensive analyses of selected reptiles’ sera using liquid chromatography mass spectrometry, leading to the identification of potentially novel anticancer agents. We hope that the discovery of molecules from these animals will pave the way for the rational development of new anticancer agents.
Roma locuta, causa finita?
Authors: Verdoodt Frans-Jos 
Published: May 2020

De Heilige Stoel, d.w.z. het hoogste bestuurslichaam van de Rooms-Katholieke Kerk, toonde tijdens de Eerste Wereldoorlog in ruime mate begrip voor de verzuchtingen van de Vlaamse beweging. In de ogen van ‘Rome’ waren die verzuchtingen terecht: op grond van hun miskenning in het verleden, verdienden de Vlamingen, na de afloop van de oorlog, een tegemoetkomende houding vanwege de burgerlijke en kerkelijke overheid. Dat de katholieke aartsbisschop Désiré Mercier (1851-1926) die tegemoetkoming radicaal bleef afwijzen, stuitte in Rome nauwelijks op begrip. En dat de kardinaal-aartsbisschop zich daarenboven steeds meer profileerde als het symbool van het verzet tegen de Duitse bezetter versterkte het ongenoegen bij sommige leden van de Romeinse Curie.De Heilige Stoel mocht dan wel oordelen dat de Vlaamse Kwestie na de oorlog moest worden beslecht, zolang die oorlog woedde, wenste men een pragmatisch standpunt in te nemen: de bezetting was beslist een kwaad, maar daarom diende men nog niet op te roepen tot een burgeroorlog.__________
Roma locuta, causa finita?
The Holy See, that is to say, the highest administrative body of the Roman Catholic Church, demonstrated a broad understanding for the aspirations of the Flemish Movement during the First World War. In the eyes of ‘Rome’ these aspirations were just: on account of the poor treatment that they had received in the past, the Flemings deserved an accommodating attitude from the civil and ecclesiastical authorities after the end of the war. The fact that Catholic archbishop Désiré Mercier (1851-1926) remained radically opposed to this accommodation was met with bewilderment in Rome. What’s more, the fact that the Cardinal-Archbishop also began to present himself more and more as the symbol of resistance to the German occupier strengthened the displeasure among some members of the Roman Curia.The Holy See could certainly proclaim that the Flemish Question needed to be settled after the war; so long as the war raged they wanted to take a pragmatic point of view: the occupation was certainly wicked, but still, one did not have to call for a civil war on its account.