bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short-distance distribution patterns of testate amoebae in an Arctic ice-wedge polygon mire (Berelekh-Indigirka lowlands, NE Siberia)
Authors: de Klerk Pim , Bobrov Anatoly , Theuerkauf Martin , Joosten Hans 
Published: August 2020

AbstractThe Arctic is experiencing substantial warming with possibly large consequences for global climate when its large soil carbon stocks are mobilized. Yet the functioning of permafrost peatlands, which contain considerable amounts of carbon, is still not fully understood. Palaeoecological studies may contribute to unravelling this functioning but require actuo-ecological calibration of the environmental proxies used. Testate amoebae may be valuable proxies for palaeoecological reconstruction, but indeed still large gaps exist regarding their present-day distribution in Arctic peatlands. This study presents the distribution of testate amoebae taxa with high (1 m) spatial resolution along a transect crossing an Arctic ice-wedge polygon mire. Whereas the polygon ridges are characterised by taxa that are known to be typical of dry environments or hydrologically indifferent, the low-lying wet settings show a mixture of wet- and dry-living taxa, indicating seasonally rapidly changing conditions. High testate amoebae concentrations were only found on the dry polygon ridges. Archerella flavum occurs in various moss species in drier polygon settings, in contrast to temperate regions where the species is exclusively known from wet sites with Sphagnum, which probably relates to the special moisture conditions associated with permafrost. To compare the results of full testate amoebae analysis with those of palynology, each surface sample was split into two parts and prepared and analysed following standard testate amoebae analysis and palynological methods, respectively. Clear differences in qualitative content were found and can be attributed to the different preparation methods and to possible small (a few cm) differences in sample location. Nevertheless, the indicative value of testate amoebae found in pollen samples adds importantly to the ecological inference of palynological studies. Overall testate amoebae research is very valuable for the recognition of past ecological settings and the accurate reconstruction of past hydrological regimes in Arctic mires. Considerably more research is, however, necessary to cover the total (ecological) diversity of testate amoebae populations in NE Siberia.
Comparison of postoperative CT- and preoperative MRI-based breast tumor bed contours in prone position for radiotherapy after breast-conserving surgery
Authors: Dong Yinping , Liu Yang , Chen Jinhu , Li Wanhu , Li Yongqing , Zhao Qian , Chen Yiru , Huang Wei 
Published: August 2020

Abstract
Objectives
To compare the target volume of tumor bed defined by postoperative computed tomography (post-CT) in prone position registered with or without preoperative magnetic resonance imaging (pre-MRI).

Methods
A total of 22 patients were included with early-stage breast invasive ductal cancer, who have undergone breast-conservative surgery and received the pre-MRI and post-CT in prone position. The MRI sequences (T1W, T2W, T2W-SPAIR, DWI, dyn-eTHRIVE, sdyn-eTHRIVE) were delineated and manually registered to CT, respectively. The clinical target volumes (CTVs) and planning target volumes (PTVs) were contoured on CT and different MRI sequences, respectively. Differences were measured in terms of consistence index (CI), dice coefficient (DC), geographical miss index (GMI), and normal tissue index (NTI).

Results
The differences of delineation volumes among CT and MRIs were significant, both in the CTVs (p = 0.035) and PTVs (p < 0.001). The values of CI and DC for sdyn-eTHRIVE registration to CT were the largest among all MRI sequences, but GMI and NTI were the smallest. No obvious linear correlation (p > 0.05) between the CI derived from the registration of CT and sdyn-eTHRIVE of CTV with the breast volume, the cavity visualization score (CVS) of CT, time interval from surgery to CT simulation, the maximum diameter of the intraoperative mass, and the number of titanium clips, respectively.

Conclusions
The CTVs and PTVs in MRI sequences were all smaller than those in CT. The pre-MRI, especially the sdyn-eTHRIVE, could be used to optimize the post-CT-based target delineation of breast cancer.

Key Points
• Registered pre-MRI to post-CT in order to improve the accuracy of target volume delineation of breast cancer.
• The CTVs and PTVs in MRI sequences were all smaller than those in CT.
• The sdyn-eTHRIVE of pre-MRIs may be a better choice to improve the delineation of CT-based CTV and PTV.
Association of butterflyfishes and stony coral tissue loss disease in the Florida Keys
Authors: Noonan Kara R. , Childress Michael J. 
Published: August 2020

AbstractSince 2014, stony coral tissue loss disease (SCTLD) has rapidly spread throughout the Florida reef tract infecting and killing dozens of coral species. Previous studies have found that corallivorous fishes, such as butterflyfishes, are positively correlated with coral disease prevalence at both local and regional scales. This study investigates the association of SCTLD infection and butterflyfish abundance and behaviors on ten reefs in the middle Florida Keys. Divers conducted video surveys of reef fish abundance and disease prevalence in June 2017, 2018, and 2019; before, during, and after the outbreak of SCTLD infections. SCTLD prevalence increased from 3.2% in 2017 to 36.9% in 2018 and back to 2.7% in 2019. Butterflyfish abundances also showed a similar pattern with a twofold increase in abundance in 2018 over abundances in 2017 and 2019. To better understand the association of individual species of butterflyfishes and diseased corals, 60 coral colonies (20 healthy, 20 diseased, 20 recently dead) were tagged and monitored for butterflyfish activity using both diver-based AGGRA fish counts and 1-h time-lapse videophotography collected in the summers of 2018 and 2019. All reef fishes were more abundant on corals with larger surface areas of live tissue, but only the foureye butterflyfish preferred corals with larger surface areas of diseased tissues. Estimates of association indicate that foureye butterflyfish were found significantly more on diseased corals than either healthy or recently dead corals when compared with the other species of butterflyfishes. Foureye butterflyfish were observed to feed directly on the SCTLD line of infection, while other butterflyfish were not. Furthermore, association of foureye butterflyfish with particular diseased corals decreased from 2018 to 2019 as the SCTLD infections disappeared. Our findings suggest that foureye butterflyfish recruit to and feed on SCTLD-infected corals which may influence the progression and/or transmission of this insidious coral disease.
Birth experience from the perspective of the fathers
Authors: Vischer Lena C. , Heun Xenia , Steetskamp Joscha , Hasenburg Annette , Skala Christine 
Published: August 2020

Abstract
Purpose
As men nowadays often attend the delivery of their own child, they also have to go through the labor period. In this study, the condition of the expectant fathers attending labor was evaluated.

Methods
In 2016, fathers who went through labor with their partners in the University medical center of Mainz were interviewed within the first days after delivery and 6 months later. They received a “Fathers questionnaire” concerning their motivation, the valuation of their attendance, their emotions during labor, and concerning the service in the labor ward. Six months later, they also received the validated Impact of Event Scale questionnaire (IES-R). In total, 318 participants answered the “Fathers’ Questionnaire”, 226 the IES-R.

Results
Father’s attendance during labor was considered to be beneficial for fathers themselves (254, 79.8%), for the mother (272, 85.5%), for the newborn child (187, 58.8%), for the relationship (234, 73.6%). Only four could not see a purpose in their attendance. 73 men (23%) felt helpless, 47 (14.8%) were overwhelmed by the situation, 116 (36.5%) felt fear, 299 (94%) were happy to be present at birth, 27 (8.5%) felt traumatized by experiencing their partners in labor. According to the IES-R, none of the 226 men surveyed showed all symptoms of post-traumatic stress disorder.

Conclusion
Childbirth is related to positive and negative emotions. Positive emotions are predominant, but come along with negative feelings. In this survey, posttraumatic stress disorder did not occur among men after delivery. Nevertheless, fathers’ needs should be kept in view.
3D ultrasound as a surgical quality control of conization in patients with severe dysplasia: a prospective study
Authors: Dückelmann Anna M. , Wordell Julia , Richter Rolf , Sehouli Jalid 
Published: August 2020

Abstract
Purpose
To compare the techniques for cone measurement with ultrasound to determine the size of the resected tissue and to evaluate parameters which may be relevant for stratifying women at risk who need surveillance when pregnant.

Methods
The present study included women with a pathological cervical biopsy. Cervical length and volume were determined by transvaginal ultrasound prior to conization. The pathologist measured the volume of the removed tissue by the fluid displacement technique and using a ruler. A repeat transvaginal ultrasound was performed during a follow-up visit. Factors affecting cone volume as well as the correlation between measurement techniques were analyzed.

Results
A total of 28 patients underwent cervical excision treatment. The mean cervical volumes measured sonographically before and after the operation were 17.72 ± 7.34 and 13.21 ± 5.43 cm3, respectively. The proportion of volume excised was 25.50 ± 17.43%. A significant correlation was found between the cone depth and the cone volume measured by the fluid displacement technique, and histopathologically and sonographically measured difference in cervical volume. The interobserver reliability coefficient was > 0.9. Analyzing influential parameters, only age affected the extent of cone volume and the correlation between the three measurement techniques.

Conclusion
Commonly applied techniques of cervical and cone measurement are equivalent and interchangeable. Our ultrasound data show variety in the volume and length of the cervix, and in the proportion of the volume excised at conization. Ultrasound measurements may help the surgeon to estimate not only the dimension of the remaining cervix but also its function.
Differential responses of macroinvertebrate ionomes across experimental N:P gradients in detritus-based headwater streams
Authors: Prater Clay , Bumpers Phillip M. , Demi Lee M. , Rosemond Amy D. , Jeyasingh Punidan D. 
Published: August 2020

AbstractDiverse global change processes are reshaping the biogeochemistry of stream ecosystems. Nutrient enrichment is a common stressor that can modify flows of biologically important elements such as carbon (C), nitrogen (N), and phosphorus (P) through stream foodwebs by altering the stoichiometric composition of stream organisms. However, enrichment effects on concentrations of other important essential and trace elements in stream taxa are less understood. We investigated shifts in macroinvertebrate ionomes in response to changes in coarse benthic organic matter (CBOM) stoichiometry following N and P enrichment of five detritus-based headwater streams. Concentrations of most elements (17/19) differed among three insect genera (Maccaffertium sp.,Pycnopsyche spp., andTallaperla spp.) prior to enrichment. Genus-specific changes in the body content of: P, magnesium, and sodium (Na) inTallaperla; P, Na, and cadmium inPycnopsyche;and P inMaccaffertiumwere also found across CBOM N:P gradients. These elements increased inTallaperlabut decreased in the other two taxa due to growth dilution at larger body sizes. Multivariate elemental differences were found across all taxa, and ionome-wide shifts with dietary N and P enrichment were also observed inTallaperlaandPycnopsyche. Our results show that macroinvertebrates exhibit distinct differences in elemental composition beyond C, N, and P and that the ionomic composition of common stream taxa can vary with body size and N and P enrichment. Thus, bottom-up changes in N and P supplies could potentially influence the cycling of lesser studied biologically essential elements in aquatic environments by altering their relative proportions in animal tissues.
Electroanalysis based on stand-alone matrices and electrode-modifying films with silica sol-gel frameworks: a review
Authors: Miecznikowski Krzysztof , Cox James A. 
Published: August 2020

AbstractSilica sol-gel matrices and its organically modified analogues that contain aqueous electrolytes, ionic liquids, or other ionic conductors constitute stand-alone solid-state electrochemical cells when hosting electrodes or serve as modifying films on working electrodes in conventional cells. These materials facilitate a wide variety of analytical applications and are employed in various designs of power sources. In this review, analytical applications are the focus. Solid-state cells that serve as gas sensors, including in chromatographic detectors of gas-phase analytes, are described. Sol-gel films that modify working electrodes to perform functions such as hosting electrochemical catalysts and acting as size-exclusion moieties that protect the electrode from passivation by adsorption of macromolecules are discussed with emphasis on pore size, structure, and orientation. Silica sol-gel chemistry has been studied extensively; thus, factors that control its general properties as frameworks for solid-state cells and for thin films on the working electrode are well characterized. Here, recent advances such as the use of dendrimers and of nanoscale beads in conjunction with electrochemically assisted deposition of silica to template pore size and distribution are emphasized. Related topics include replacing aqueous solutions as the internal electrolyte with room-temperature ionic liquids, using the sol-gel as an anchor for functional groups and modifying electrodes with silica-based composites.
Contact force network evolution in active earth pressure state of granular materials: photo-elastic tests and DEM
Authors: Leśniewska D. , Nitka M. , Tejchman J. , Pietrzak M. 
Published: August 2020

AbstractThe paper deals with a quasi-static behaviour of cohesion-less granular material in active earth pressure state. Photo-elastic model tests on a rigid wall, translating out of the granular material, are analyzed. Grain crushing tests are used to estimate the range of contact forces during the model tests. Substitute granular material (low optical sensitivity glass granules) is employed. The focus is on the evolution of contact force network with deformation of granular material. The model tests are simulated using the discrete element method (DEM) to compare physical and numerical full-field force network structure and the maximum/minimum stress level. The same model geometry, loading scheme and grain size distribution, as in the model tests, are accepted in DEM simulations, although only a single layer of grains is modelled. DEM model correctly predicts the overall structure of the force network and its characteristic features, including localization. It also gives the stress level close to the experimental one and properly identifies the areas of phase transitions.
Graphical Abstract
Tuberculosis and viral hepatitis in patients treated with certolizumab pegol in Asia-Pacific countries and worldwide: real-world and clinical trial data
Authors: Lau Chak Sing , Chen Yi-Hsing , Lim Keith , de Longueville Marc , Arendt Catherine , Winthrop Kevin 
Published: August 2020

Abstract
Introduction/objectives
To evaluate the incidence rate (IR) of tuberculosis (TB) and viral hepatitis B and C (HBV/HCV) during certolizumab pegol (CZP) treatment, worldwide and in Asia-Pacific countries, across clinical trials and post-marketing reports (non-interventional studies and real-world practice).

Method
CZP safety data were pooled across 49 clinical trials from 1998 to June 2017. Post-marketing reports were from initial commercialization until March 2015 (TB)/February 2017 (HBV/HCV). All suspected TB and HBV/HCV cases underwent centralized retrospective review by external experts. Incidence rates (IRs) were calculated per 100 patient-years (PY) of CZP exposure.

Results
Among 11,317 clinical trial patients (21,695 PY), 62 TB cases were confirmed (IR 0.29/100 PY) including 2 in Japan (0.10/100 PY) and 3 in other Asia-Pacific countries (0.58/100 PY). From > 238,000 PY estimated post-marketing CZP exposure, there were 31 confirmed TB cases (0.01/100 PY): 5 in Japan (0.05/100 PY), 1 in other Asia-Pacific countries (0.03/100 PY). Reported regional TB IRs were highest in eastern Europe (0.17/100 PY), central Europe (0.09/100 PY), and Mexico (0.16/100 PY). Across clinical trials, there was 1 confirmed HBV reactivation and no HCV cases. From > 420,000 PY estimated post-marketing CZP exposure, 5 HBV/HCV cases were confirmed (0.001/100 PY): 2 HCV reactivations; 1 new HCV; plus 2 HBV reactivations in Japan (0.008/100 PY).

Conclusions
CZP TB risk is aligned with nationwide TB rates, being slightly higher in Asia-Pacific countries excluding Japan. Overall, TB and HBV/HCV risk with CZP treatment is currently relatively low, as risk can be minimized with patient/physician education, screening, and vigilant treatment, according to international guidelines.

Key Points:• TB rates were highest in eastern/central Europe, Mexico, and Asia-Pacific regions.• With the implementation of stricter TB screening and risk evaluations in 2007, especially in high TB incidence countries, there was a notable reduction TB occurrence.• Safety profile of biologics in real-world settings complements controlled studies.• TB and hepatitis (HBV/HCV) risk with certolizumab pegol (CZP) treatment is low.
Mechanical Manipulation of Electrical Behaviors of Piezoelectric Semiconductor Nanofibers by Time-Dependent Stresses
Authors: Huang Haoyu , Qian Zhenghua , Yang Jiashi 
Published: August 2020

AbstractWe study electric currents in a piezoelectric semiconductor fiber under a constant voltage and time-dependent axial stresses applied locally. From a nonlinear numerical analysis based on a one-dimensional phenomenological model using the commercial software COMSOL, it is found that pulse electric currents can be produced by periodic or time-harmonic stresses. The pulse currents can be tuned by the amplitude and frequency of the applied stress. The result obtained provides a new approach for the mechanical control of electric currents in piezoelectric semiconductor fibers and has potential applications in piezotronics.
Trump’s Trade Policy, BREXIT, Corona Dynamics, EU Crisis and Declining Multilateralism
Authors: Welfens Paul J. J. 
Published: August 2020

AbstractSince 1991 there has been a reinforcement of the World Market Economy, not least since China and the, then new Russian Federation have joined the World Trade Organization and because of EU Eastern enlargement and ASEAN integration deepening, while the Transatlantic Trade and Investment Partnership (TTIP) and Trans-Pacific Partnership (TPP) negotiations seemed to indicate stronger regional integration dynamics. With the Trump Administration, the situation has changed dramatically as President Trump is supportive of neither multilateralism in general nor of the EU, which is weakened through BREXIT, in particular. Trump’s focus on the US merchandise trade balance deficit is ill-placed and import tariffs imposed on China seem to be excessive as the optimum tariff rate is miscalculated on the basis of the traditional formula – while a new adequate formula would include the role of sectoral US outward FDI stocks. Asia, the EU and the US could define fighting the Corona World Recession as a global public good, but the United States is weakened in the corona pandemic crisis; the EU is facing serious problems in avoiding a Euro Crisis 2 problem and the €750 billion EU loan package could undermine the Eurozone’s stability while being inadequate to minimize the risk of a Euro Crisis 2. At the same time, the prospects for EU cooperation are declining due to political disappointment concerning the national corona pandemic policy in some member countries. An effective anti-corona pandemic policy would mean to organize a consistent EU-ASEAN cooperation or a G20 cooperation with a later extension to UN Organizations, including the IMF, the World Bank and the WHO. Post-corona, global governance could change strongly because of the long-term political scarring effects of the pandemic shock which could undermine EU and Western stability. Networked international leadership in support of multilateralism is an innovative – but difficult - option for EU-ASEAN-Mercosur.
A three-year longitudinal study of healthy lifestyle behaviors and adherence to pharmacological treatments in newly diagnosed patients with acute coronary syndrome: hierarchical linear modeling analyses
Authors: Greco Andrea , Brugnera Agostino , D’Addario Marco , Compare Angelo , Franzelli Cristina , Maloberti Alessandro , Giannattasio Cristina , Fattirolli Francesco , Steca Patrizia 
Published: August 2020

Abstract
Aim
Healthy lifestyle behaviors and a good adherence to pharmacological treatments are important predictors of lower recurrence rates and better overall outcomes among patients with an established acute coronary syndrome (ACS). The present study sought to investigate the longitudinal trajectories of these behaviors years after the onset of an ACS.

Subject and methods
We recruited a sample of 275 newly diagnosed consecutive patients at their first ACS event (mean age: 57.1 ± 7.87 years; 84% males) admitted to a cardiac rehabilitation program from three large public hospitals in Northern Italy. Patients completed a battery of sociodemographic questionnaires, which evaluated healthy lifestyles (smoking status, alcohol intake, diet, and physical activity) and adherence to pharmacological treatments, at five time-points (pre-event, 6-, 12-, 24-, and 36-month follow-ups). Longitudinal trajectories were examined through hierarchical (generalized) linear models, controlling for several demographic and clinical variables.

Results
We found significant changes in all healthy lifestyles from pre-event to the 6-month follow-up, suggesting the adoption of healthier behaviors soon after the cardiac event. However, from the 6-month up to the 3-year follow-up, patients experienced small but significant declines in their self-reported levels of healthy dietary behaviors and physical activity. Further, we found that the odds of being at medium risk of non-adherence to the pharmacological treatments significantly increased over the course of 3 years.

Conclusion
Given the negative long-term trajectories in specific lifestyles and adherence to pharmacological treatments, cardiac rehabilitation programs are suggested to provide repeated psychological interventions aimed at fostering patients’ capabilities to self-regulate their habitual behaviors.