bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful treatment of xanthelasma palpebrarum with a combination of radiofrequency ablation and wound suturing
Authors: Singh Anupama , Tiwary Pankaj Kumar , Jha Abhijeet Kumar , Zeeshan Md. , Ranjan Amit 
Published: August 2020

AbstractBackgroundXanthelasma palpebrarum is a common disfiguring condition of eyelids often causing cosmetic concern and psychological distress. Various treatment modalities have been used to clear the lesions but none have been found to be fully satisfactory.AimsTo evaluate a novel combination of radiofrequency (RF) ablation and primary wound closure for treatment of xanthelasma palpebrarum (XP).MethodsForty‐five patients were selected after clinical examination and grading of lesions. Radiofrequency ablation was used to remove the lesion followed by suturing of the wound. Efficacy of treatment was evaluated on the basis of clinical examination and photographic images.ResultsExcellent response was seen in all patients. Of these, in 43 patients complete clearance could be achieved in a single sitting. In the other 2, an additional sitting of RF was done because of the presence of either multiple lesions or significant projection from the main lesion. Recurrence was seen in only two patients at the end of one year.ConclusionRadiofrequency removal combined with wound closure showed excellent response with good cosmetic result, no scarring, and rare relapse at end of 1 year. This was achieved in 43(96%) of the total 45 patients in a single sitting.
Consensus report on the use of PN‐HPT™ (polynucleotides highly purified technology) in aesthetic medicine
Authors: Cavallini Maurizio , Bartoletti Emanuele , Maioli Laura , Massirone Alberto , Pia Palmieri Isabella , Papagni Marco , Priori Maurizio , Trocchi Gloria ,   As Members of The Polynucleotides HPT™ Priming Board, Collegio Italiano delle Società Scientifiche di Medicina Estetica (Italian College of the Aesthetic Medicine Scientific Societies) — SIME, AGORÀ, SIES
Published: August 2020

AbstractBackgroundInjective procedures using polynucleotides‐based products to promote dermal rejuvenation and revitalization are steadily evolving, yet no structured protocols are available that discuss and provide guidance in aesthetic treatments with highly purified polynucleotides. The goal of this document was to provide consensus‐based recommendations for the safe and effective use of Polynucleotides Highly Purified Technology™ (PN‐HPT™) devices for skin rejuvenation.Patients/MethodsA team of eight experts with extensive experience in treatments for skin rejuvenation and revitalization integrated the best available evidence and clinical judgment and devised a series of practical guidance to support dermatologists, plastic surgeons, and aesthetic physician in the use of PN‐HPT™ products, alone and in combination, in aesthetic medicine.ResultsFor most items, the expert group achieved a majority consensus. “Recommendations” (consensus >80%) were reached for the face, periocular area, décolleté and neck, hands, scalp, and stretch marks. Recommendations include details of techniques, information on dosage, volumes to be injected, and the ideal number of required treatment sessions, as well as time intervals between them for different areas of face and body. A lower agreement level of 60% was reached on but one item related to the initial treatment cycle for the face, leading to a “Consensus statement” for that area instead of a full “Recommendation.”ConclusionThe expert consensus illustrates the value of natural‐origin, highly purified polynucleotides (PN‐HPT™) as biostimulatory booster strategy for skin priming and revitalization of face and body and provides a detailed guide for the use.
The role of a shelf‐ready, human‐derived, soft tissue injectable adipose matrix for facial volume correction
Authors: Gold Michael H. , Andriessen Anneke , Day Doris , Dayan Steven H. , Fabi Sabrina G. , Goldberg David J. , Kaufman Joely , Lorenc Z. Paul , Mandy Steven H. 
Published: August 2020

AbstractBackgroundSynthetic soft tissue fillers frequently used to restore facial volume do not provide a regenerative framework, limiting their sustained efficacy. Autologous fat transfer for facial rejuvenation supports tissue regeneration but has unpredictable outcomes depending on the quality of harvesting, processing, and implantation.AimsExploration of the pros and cons of available tissue fillers and the role of an injectable Allograft Adipose Matrix (AAM) for facial rejuvenation.MethodsThe results of a literature review conducted by two clinicians with extensive experience in this field were discussed by a panel of dermatologists and surgeons who regularly treat patients with signs and symptoms of facial aging. A manuscript was prepared and reviewed by the panel taking into account the evidence and their clinical experience treating patients for facial rejuvenation.ResultsFacial rejuvenation needs to address the volume deficiency and repositioning of ptotic soft tissues. Frequently used synthetic fillers are suitable candidates for improving the facial appearance of fine lines and for molding. A better understanding of facial volume loss has allowed the use of adipose fat cells for facial rejuvenation. The injectable AAM is readily available and provides a regenerative framework for sustainable results. Prospective clinical and randomized studies support the effective and safe use of AAM for facial rejuvenation.ConclusionAAM may offer an alternative to synthetic fillers and autologous fat implantation in the face without the cumbersome process of fat harvesting and processing. More robust studies are to confirm the positive results obtained in smaller studies using the soft tissue bio stimulatory injectable.
The Role of Substantive Actions in Sensemaking During Strategic Change
Authors: Weiser Ann‐Kristin 
Published: August 2020

AbstractWhile prior research has provided rich insights into how strategic change unfolds through sensemaking and sensegiving, the existing literature conceptualizes these activities largely as cognitive and discursive accomplishments. Although leaders commonly also modify organizational structures, processes, and practices, prior research has paid little attention to how these substantive actions shape the interpretive change process. Based on a qualitative case study of a top‐management‐led change initiative, I identify four ways in which substantive actions can support strategic change beyond the influence of discursive sensegiving: actualizing, concretizing, formalizing, and materializing. I incorporate my findings into an integrative model that relates my observations of the distinct influence of different types of sensemaking cues to differences in the sensemaking content and describes sensemaking during strategic change not just as an intellectual but as a multimodal process.
Factors associated with the number of microorganisms on the tongue surface in patients following acute stroke
Authors: Furuya Junichi , Beniya Akane , Suzuki Hiroyuki , Hidaka Rena , Matsubara Chiaki , Obana Michiyo , Yoshimi Kanako , Yamaguchi Kohei , Hara Koji , Nakagawa Kazuharu , Nakane Ayako , Tohara Haruka , Minakuchi Shunsuke 
Published: August 2020

AbstractBackgroundOral hygiene management of patients with acute stroke is important for preventing aspiration pneumonia and ensuring oral intake. The tongue coating score can be useful for evaluating the oral hygiene level since it reflects the microorganism number on the tongue surface in elderly patients. However, the relationship between the number of oral microorganisms and the tongue coating score in patients with acute stroke remains unclear.ObjectivesWe aimed to investigate the relationships between the microorganism number on the tongue surface and oral factors, including tongue coating score, tongue surface moisture level and tongue function.MethodsThis cross‐sectional study enrolled 73 patients with acute stroke who were hospitalised at an acute care hospital and underwent dental intervention. Potential explanatory factors, including sex, age, Glasgow Coma Scale score, tongue coating score, tongue surface moisture level, nutrition intake method, number of functional teeth and tongue function, were evaluated. Logistic regression analysis determined their association with the microorganism number on the tongue surface.ResultsThe tongue coating score (odds ratio: 1.31) and tongue surface moisture level (odds ratio: 1.10) were significantly associated with increased microorganism numbers on the tongue surface.ConclusionThe tongue coating score, which reflects the actual number of microorganisms on the tongue surface, could be an effective tool for evaluating oral hygiene level in patients with stroke. Moreover, reducing oral microorganisms in saliva through oral hygiene management, including removing the tongue coating, could contribute towards the prevention of aspiration pneumonia.
Oral mucosal lesions in psoriatic patients based on disease severity and treatment approach
Authors: Olejnik Maria , Osmola‐Mańkowska Agnieszka , Ślebioda Zuzanna , Adamski Zygmunt , Dorocka‐Bobkowska Barbara 
Published: August 2020

AbstractBackgroundThis observational case‐control study was designed to investigate the frequency of oral lesions in psoriatic patients and to identify an association between mucosal involvement, the severity of the disease, and a form of treatment.MethodsOne hundred twenty‐seven patients diagnosed with psoriasis were enrolled in this study from November 2018 to September 2019. The oral mucosa evaluation was based on the clinical appearance, location, and morphology of the lesions. All patients completed a general medical history and a Dermatology Life Quality Index (DLQI) questionnaire. The severity of skin involvement was assessed using the Psoriasis Area and Severity Index (PASI) scale.ResultsThe most common oral lesions in patients with psoriasis were found to be fissured (FT), white coated (CT), and geographic tongue (GT). A significantly lower prevalence of GT was evident in the group managed with a new class of biological drugs and smokers. There appeared to be no association between the oral manifestation and the PASI score. FT appeared significantly more often in patients that experienced an extremely large effect of psoriasis on their quality of life as determined by the DLQI questionnaire and smokers. Only 25% of patients presented normal oral mucosa.ConclusionsTongue lesions seem to be associated with skin psoriasis regardless of the treatment. The severity of the disease, according to the PASI scale, does not influence mucosal involvement. The type of treatment may affect the prevalence of oral lesions. Further investigations are required to confirm the influence of biological therapies on mucosal improvement.
Distinct microRNA expression profiles in saliva and salivary gland tissue differentiate patients with primary Sjögren's syndrome from non‐Sjögren's sicca patients
Authors: Sembler‐Møller Maria Lynn , Belstrøm Daniel , Locht Henning , Pedersen Anne Marie Lynge 
Published: August 2020

AbstractObjectivesIncreasing evidence suggests that aberrant expression of microRNAs (miRNAs) is involved in the pathogenesis of primary Sjögren's syndrome (pSS). The aim was thus to characterize the miRNA profile in saliva, salivary gland tissue, and plasma from patients with pSS and compare findings with those of patients having Sjögren‐like disease (non‐pSS). In addition, to correlate miRNA levels and clinicopathological features of pSS.MethodsmiRNA real‐time quantitative polymerase chain reaction was performed on saliva, plasma, and salivary gland tissue samples from 24 patients with pSS and 16 non‐pSS in 384‐well plates. T test was used for comparison of miRNA profiles, followed by Benjamini‐Hochberg correction. The discriminatory power of miRNAs was evaluated by receiver‐operating characteristic curves, and Pearson/Spearman correlation was used for correlation analyses.ResultsIn saliva, 14 miRNAs were significantly differentially expressed between pSS and non‐pSS, including downregulation of the miR‐17 family in pSS. In salivary gland tissue of patients with pSS, miR‐29a‐3p was significantly upregulated. Plasma miRNAs did not differ between the two groups, although the miR‐17 family tended to be downregulated. The combination of miR‐17‐5p and let‐7i‐5p in saliva yielded an area under curve of 97% (CI 92%‐100%). Several miRNAs correlated significantly with one another and with salivary flow rates and histopathology.ConclusionOur findings indicate that the miRNA expression profile in saliva may enable to discriminate between pSS and non‐pSS patients. However, further validation in larger cohorts is needed as well as functional analyses of the miRNAs of interest.
Making and maintaining relationships through the prism of the dark triad traits: A longitudinal social network study
Authors: Rogoza Radosław , Danieluk Barnaba , Kowalski Christopher Marcin , Kwiatkowska Katarzyna , Kwiatkowska Maria Magdalena 
Published: August 2020

AbstractObjectiveWe investigated how Dark Triad traits influence the development and maintenance of social relations.MethodParticipants completed the Short Dark Triad questionnaire and a measure of social relations at three time points: at the beginning of their first year in high school, 3 months later, and at the end of their first year. We investigated whether the Dark Triad traits are stable over time using Multilevel Modeling (N = 265; 59.6% girls), and how Dark Triad traits predict incoming and outgoing agentic and communal relations using Temporal Exponential Random Graph Models (N = 192; 60.4% girls).ResultsOverall, the Dark Triad traits were stable over a one‐year period. Narcissism did not predict an increase in communal and agentic relations in the short‐term, but predicted slightly less incoming communal and more agentic relations in the long‐term. In the short‐term, Machiavellianism predicted a small increase while psychopathy predicted a small decrease in the incoming agentic and communal relations. In the long‐term, however, neither Machiavellianism nor psychopathy was a significant predictor of any incoming relations.ConclusionsOur results shed new light on the dynamics of making and maintaining social relations through the prism of the Dark Triad traits.
Did Marketplace coverage really offer financial protection? Financial gains from the Affordable Care Act's private insurance policies among the previously uninsured
Authors: Zewde Naomi 
Published: August 2020

AbstractWhile the Affordable Care Act successfully expanded health insurance access, the law's private insurance component drew far fewer participants than projected. This study investigates the attractiveness of Marketplace insurance relative to uncompensated care provisions for those who remain uninsured. Using restricted‐access Medical Expenditure Panel Survey data, I find that for one in four previously uninsured consumers, bankruptcy costs less than meeting the deductible of the subsidized benchmark policy. Marketplace insurance reduces spending in only the top 3% most catastrophic potential scenarios these consumers face, on average. Net financial gain is more common among individuals in poor health (11% vs. 1%) or with assets to protect (3% vs. <1%). High‐deductible insurance aims to protect wealth in catastrophic scenarios. However, hospitals substantially discount care for the uninsured in such scenarios. High‐deductible coverage might not be an effective driver of financial security for the uninsured, which may help to explain low Marketplace enrollment.
Low allergen content of commercial baby foods
Authors: Netting Merryn J , Gold Michael S , Palmer Debra J 
Published: August 2020

AimIntroduction of allergenic solid foods, especially peanut and hen's egg reduces the risk of food allergy development in early childhood. Ideally, parents will offer their infants home‐prepared foods; however, many rely on the availability of convenient ready to purchase infant foods. This audit aimed to assess the major food allergen content of commercial infant foods.MethodsInfant foods available for sale in 2019 in Australia were the focus of this audit. The major food allergens investigated were peanut, tree nuts, hen's egg, cows milk, wheat, fish, shellfish, soy, sesame and lupin. Websites of infant food manufacturers and major supermarkets were used to identify ingredient lists of infant foods available for purchase. Where ingredients listings were unavailable this information was sourced directly from the product labels in the supermarket.ResultsFourteen companies were identified, manufacturing over 251 foods specifically for the infants aged less than 1 year of age. Although there were many choices available containing wheat (27 products) and cows milk proteins (73 products), none contained peanut, tree nuts, sesame, shellfish or lupin.ConclusionsDespite infant feeding advice encouraging early introduction to food allergens, of 251 commercial baby foods surveyed only 1% contained egg and none contained peanut, the most common food allergies in young Australian infants. This low food allergen content may be disadvantageous for infants fed mostly commercial infant foods as they are unlikely to be exposed to sufficient amounts of the major food allergens on a regular basis during infancy.
A dis‐ordered personality? It’s time to reframe borderline personality disorder
Authors: Brand Gabrielle , Wise Steve , Walpole Katherine 
Published: August 2020

Accessible summaryWhat is known on the subject

Integrating strengths‐based, co‐produced, consumer‐driven resources into mental health workforce education has the potential to dissolve hierarchical mental health care relationships.

What the paper adds to existing knowledge

Humanities‐based pedagogy that draws from photography and multi‐voiced narratives is a powerful reflective learning tool to bridge clinical and human experiences of Borderline Personality Disorder (BPD).

The Depth of Field reflective learning methodology aims to provoke, prod, reveal and challenge assumptions and/or unconscious bias towards BPD and stimulate raw and reflective discussions that have the potential to inspire critical reflection and move health professionals towards more humanistic, recovery centred models of mental health care.

What are the implications for mental health nursing

At the core of co‐production in research, education and practice lies a reciprocal, transformational learning experience. This relationship needs to be further explored in order to reframe mental health education that honours and legitimizes consumers as experts of their own lives and recovery experiences.
The importance of historical ecology for interpreting evolutionary processes in plants of oceanic islands
Authors: Stuessy Tod F. 
Published: August 2020

AbstractOceanic islands and archipelagos are natural laboratories for investigating patterns and processes of evolution. Islands change with the course of time, resulting in a dynamic ontogeny over millions of years. The combined forces of tectonic plate subsidence and erosion from waves, wind, and rainwater bring about substantial geomorphological change over millions of years, until islands eventually disappear under the sea. Added to these long‐term natural changes to the environment of the islands are the changes caused by human activities in recent centuries. After humans reach a previously unpopulated island, they utilize the natural resources for their own survival, cutting forests for making houses, boats, and firewood. The size of the human population and the length of time on the island determine the degree of environmental impact. Evolutionary processes in plants of oceanic islands take place during ontogeny of the islands, resulting in population divergence, speciation, and hybridization. Due to the dramatic alterations suffered by many islands over millions of years, the present patterns of distribution and ecology of species within endemic groups may have little to do with the patterns when the species originated. Understanding these environmental changes is fundamental to infer a founder effect, reasons for levels of genetic variation within and among populations, and modes of speciation. Special caution must be exercised while making comparisons between groups located on islands of different geological ages and that have endured differing environmental modifications from humans. Examples are provided from the Juan Fernández Archipelago and Lord Howe Island.
Bioavailability, rheology, and sensory evaluation of mayonnaise fortified with vitamin D encapsulated in protein‐based carriers
Authors: Khan Wahab Ali , Butt Masood Sadiq , Pasha Imran , Saeed Muhammad , Yasmin Iqra , Ali Maratab , Azam Muhammad , Khan Muhammad Shahroz 
Published: August 2020

AbstractVitamin D lost its functionality during processing and storage, thus, encapsulation with proteins is desirable to preserve bioactivity. The aim of the current study was to develop encapsulated vitamin D fortified mayonnaise (VDFM) using whey protein isolates (WPI) and soy protein isolates (SPI) as encapsulating materials in three different formulations, that is, 10% WPI, 10% SPI, and 5/5% WPI/SPI. Increased shear stress decreased the apparent viscosity along with significant effects on the loss modulus of VDFM. WPI encapsulates showed better results as compared to SPI. WPI based VDFM (M1) depicted the best results in terms of size and dispersion uniformity of oil droplets. Hue angle and total change differed significantly among treatments. The highest value for overall acceptability was acquired by M3 (5:5%WPI:SPI‐encapsulates) thus proceed for in vivo trials. Serum vitamin D level was significantly higher in the encapsulated VDFM rat group (58.14 ± 6.29 nmol/L) than the control (37.80 ± 4.98 nmol/L). Conclusively, WPI and SPI encapsulates have the potential to improve the stability and bioavailability of vitamin D.
Effect of laver powder on textual, rheological properties and water distribution of squid (Dosidicus gigas) surimi gel
Authors: Yang Rong , Xu Anqi , Chen Yanting , Sun Nan , Zhang Jinjie , Jia Ru , Huang Tao , Yang Wenge 
Published: August 2020

AbstractIn order to ameliorate the gel quality of Dosidicus gigas surimi, the effects of laver powder on gel properties, rheological properties, and water‐holding capacity (WHC) were investigated. Results indicated that the addition of laver powder could significantly increase the hardness, chewiness, and breaking force of surimi gels. However, the texture indexes and gel strength began to decline when additional amount exceeded 0.6%. Rheological results demonstrated that the addition of laver powder increased the storage modulus (G′) and viscosity of surimi, prolonged protein denaturation temperature in surimi gels. Moreover, the WHC of surimi gel was improved with the increase of laver powder. Further analyses in low‐field nuclear magnetic resonance revealed that laver powder could shorten the transverse relaxation time, enhanced the combination with water, and altered the distribution of different water categories. The proportion of bound water and immobilized water reached its maximum and minimum at 0.6% of laver powder, respectively. Correlation analyses showed that WHC of surimi gel was negatively correlated well with the proportion of loose‐bound water, but positively correlated with the strong‐bound water and free water. In conclusion, the results supported that 0.6% was the optimal additional amount of laver powder for the squid‐based surimi production based on the current ingredients of surimi products.