bluuebunny/crossref_metadata_2025_split huggingface dataset:
Преваленција на метаболички синдром кај пациенти со шизофренија во Центарот за ментално здравје "Пролет", Психијатриска болница – Скопје
Authors: Isjanovski Viktor , Isjanovski Igor 
Published: November 2020

Шизофренијата е поврзана со зголемен ризик од кардио-метаболички морбидитет и морталитет. Метаболичкот синдром (МС) e релевантен предиктор за морбидитет и морталитет на кардиоваскуларните заболувања, исто така, се покажа дека е поприсутен кај пациенти со шизофренија. Цел на ова истражување беше да ја утврдиме преваленцијата на МС во примерок од пациенти со шизофренија во Центарот за ментално здравје - "Пролет", Психијатриска болница - Скопје и потенцијалните ризик фактори поврзани со него. Материјали и методи: примерокот се состои од 50 пациенти со шизофренија. Кај сите пациенти е земена венска крв за да се одреди нивото на холестерол HDL, триглицериди и гликоза, измерена е телесна тежина, телесна висина и обемот на половината. МС е дефиниран според критериумите за Национална програма за холестеролска програма за возрасни третман - панели III (NCEP ATP III). Резултати: Преваленцијата на МС кај пациенти со шизофренија изнесуваше 46,0%. Се покажа дека зголемувањето на индексот на телесна маса (BMI) е значително поврзано со преваленцијата на МС. Заклучок: Оваа студија покажала висока преваленција на МС кај пациенти со шизофренија и дека BMI може да биде фактор на ризик во развојот на МС. Оваа информација е клинички релевантна бидејќи BMI рутински се мери во психијатриска пракса и може да се користи за следење на развојот на МС кај пациентите со шизофренија.
Cor triatriatum sinister - ретка вродена срцева мана- наши искуства во дијагнозата и третманот во детска возраст
Authors: Kuzevska-Maneva Konstandina , Kacarska Rozana , Gjurkova- Angelovska Beti , Jovanovska Valentina , Neshkovska-Shumenkovska Marija , Maneva Elita , Ilic Slobodan , Dukic Milan , Cadikovski Vladimir 
Published: November 2020

Cor triatriatum sinister е ретка срцева мана кај која левата преткомора е поделена на два дела со фибромускулна мембрана. Проксималната преткомора ги прима пулмоналните вени заедно со крвта која тие ја носат, а дисталната или (вистинска) преткомора е вообичаено празна и таа е поделена од комората со митралната валвула. Има постојана комуникација помеѓу двата дела на поделената преткомора преку која крвта се пренасочува кон левата комора. Маната е многу ретка, најчесто е изолирана, но може да оди во комбинација со други срцеви мани. Презентираме случаи на две деца на возраст од 8 и 3 години во времето кога е поставена дијагнозата. Кај обете причина за дијагнозата бил замор и чуен срцев шум. За поставување на дијагнозата беа користени анамнезата, клиничките знаци и симптоми, ЕКГ, рендген на срце и бели дробови и златниот стандард - ехокардиографијата. Дефинитивно излекување беше направено со изведување на кардиохируршка ресекција на фибромускулната мембрана со користење на екстракорпорална циркулација. Потребно е регуларно периодично следење на децата со цел откривање на доцни компликации од типот на нарушувања на срцевиот ритам.
Tay Sachs-ова болест -приказ на случај
Authors: Isjanovski Igor , Golubovik Arsovska Milena 
Published: November 2020

Tay Sachs-овата болест е ретко нарушување, генетски наследено од родители на дете. Тоа е предизвикано од отсуство на ензим кој помага во разградувањето на масните супстанци. Овие масни супстанции, наречени ганглиозиди, се издигнуваат до токсични нивоа во мозокот на детето и влијаат врз функцијата на нервните клетки. Со напредување болеста, детето губи мускулна контрола. На крајот, доведува до слепило, парализа и смрт.Најчесто новороденчето почнува да покажува симптоми на возраст од околу 6 месеци. Знаци и симптоми на Tay Sachs-овата болест можат да бидат: губење на моторни вештини, губење на способноста за превртување, седење или ползење. Потоа следат напади, губење на слухот и неможност за движење, зголемени реакции кога бебето слуша гласни звуци, губење на видната острина, појава на "Cherry-red" дамки во очите, мускулна слабост
New Antiarrhythmic Agent to Stabilize Functional Activity of Rat Heart Sinus Node Cardiomyocytes
Authors: Mirzoyan Ruben S. , Turilova Antonina I. , Gan’shina Tamara S. , Avdyunina Nina I. , Pyatin Boris M. , Meshchaninova Alexandra D. , Rodina Anastasia S. , Shagaleeva Olga Yu. , Zolotarev Valentin I. , Sutyagin Pavel V. 
Published: November 2020

Introduction: The aim of this study was to explore the antiarrhythmic activity of the new antiarrhythmic drug, succinic acid ester of 5-hydroxyadamantane-2-one (ADK-1110) and its effect on the functional activity of rat heart sinus node.
Materials and methods: Experiments were performed on 80 non-linear white awake male rats weighing 200 g, using calcium chloride and aconitine arrhythmia models. The ECG was recorded from all the animals in the II standard lead before the start of the experiment. The effect of ADK-1110 on the electrical activity characteristics of rat heart sinus node pacemakers in vitro was studied on 26 outbred Wistar rats of both sexes with a body weight of 160 to 200 g, using the microelectrode technique.
Results and discussion: The compound significantly exceeds the known reference drugs in terms of the antiarrhythmic in­dex. The agent also surpasses our previously proposed adamantane derivative ADK-1100 on calcium chloride model and is not inferior to the aconitine one. The electrophysiological analysis of the sinus node pacemaker cardiomyocytes character­istics in vitro under the influence of ADK-1110 revealed that the compound expands the area occupied by true pacemakers.
Discussion: The obtained data indicate the presence of properties of antiarrhythmics of classes I, III, and IV in ADK-1110. The indicated functional remodeling stabilizes the functional activity of the central part of the sinus node.
Conclusion: ADK-1110 stabilizes the functional activity of the central part of the sinus node. ADK-1110 also has a cerebrovascular anti-ischemic property.
Religion, European Elections and EU politics
Authors: Foret François , Mondo Emilie 
Published: November 2020

L’objectif de cet article est de mieux saisir la résurgence de la religion dans l’agenda politique d’une Europe laïque. L’accent est placé ici sur l’Union européenne (UE). Le facteur religieux est envisagé tour à tour comme un facteur d’influence sur les attitudes et les comportements politiques, comme une composante idéologique et partisane, et en tant qu’enjeu politique controversé. Nous analysons ainsi les effets du facteur religieux lors des précédentes élections européennes en tant qu’élément cadrant la perception de l’intégration européenne ainsi que le vote. Nous documentons ensuite la crise qui affecte la famille démocrate-chrétienne incarnée par le Parti populaire européen (PPE) et les récits concurrents sur la religion visant à revendiquer le leadership dans la redéfinition de l’idéologie centrale et des démarcations de cette famille politique. Deux études de cas sont développées : la « crise hongroise » et la politique identitaire promue par Viktor Orban ; et le processus Spitzenkandidaten destiné à sélectionner le candidat du PPE briguant la présidence de la Commission européenne. Enfin, nous étudions le traitement de la religion comme une question politique au sein du Parlement européen (PE), et l’envisagerons aussi en tant qu’éventuelle pomme de discorde pour la législature 2019-2024.
Multiple pulmonary nodules presenting a difficult diagnostic challenge
Authors: Turrin Martina , Tinè Mariaenrica , Semenzato Umberto , Cosio Manuel , Saetta Marina , Lokar Oliani Kim 
Published: November 2020

We describe the case of a 56 years-old man with a subacute onset of symptoms mimicking a granulomatosis with polyangiitis. He was admitted to our hospital with acute respiratory failure requiring oxygen therapy, fever and crusted rhinitis. Despite initial improvement in radiological and clinical features with a steroids therapy, his condition worsened rapidly and he was re admitted to our department with ARDS. Despite antibiotic, antiviral and antifungal therapy, an endotracheal intubation was necessary and ultimately the patient passed away. Only a histological examination on autopsy had shown the presence of a diffuse Anaplastic Large Cell Lymphoma (ALCL), a rare type of non-Hodgkin lymphoma (NHL) originated from mature post-thymic T cells. It represents 1–3% of NHL. Different subtypes have been described: Kinase (ALK)-negative ALCL, ALK-positive ALCL and breast implantassociated ALCL. ALK-negative ALCL affects mainly old males and has the worst prognosis.
Upaya Menjaga Keseimbangan Pekerjaan Dengan Keluarga
Authors: Marbun Purim 
Published: November 2020

AbstractThis research has motivated by the fact in the field that to balance the job and the family is problem of the most people today, especially of the servant of God (pastor, priest, lecturers, etc). The are faced with the choice of priority between family and work. Research by Keene and Quadgno’s explain that 60% of working adults find it difficult to achieve work balance with the family. The research method used to discuss this topic is a qualitative research study with a literature study approach by discussing various literatures related to the research topic. The researcher read, analyzed and found the issues that caused the imbalance between work and family. The final results of this study after alternatives and strategies to balance job with family life.Keywords: Job; Family; BalanceAbstrakPenelitian ini dilatarbelakangi fakta di lapangan bahwa keseimbangan pekerjaan dengan kehidupan keluarga merupakan persoalan mayoritas masyarakat masa kini secara khusus para hamba Tuhan (pendeta, gembala, dosen, dll). Mereka diperhadapkan pada pilihan mengutamakan keluarga atau pekerjaan. Penelitian Keene dan Quadagno menyebutkan bahwa 60 % orang dewasa yang bekerja sulit mencapai keseimbangan pekerjaan dengan keluarga. Metode penelitian yang digunakan membahas topik ini ialah studi penelitian kualitatif dengan pendekatan studi pustaka dengan membahas berbagai literatur terkait dengan topik penelitian. Peneliti membaca dan menganalisis serta menemukan masalah penyebab ketidakseimbangan pekerjaan dengan keluarga. Hasil akhir dari penelitian ini menawarkan strategi dan upaya menyelaraskan pekerjaan dengan waktu bersama keluarga. Kata Kunci: Pekerjaan; Keluarga; Keseimbangan
Etika Guru Agama Kristen Dan Relevansinya Terhadap Pendidikan Iman Naradidik
Authors: Nainggolan Alon Mandimpu , Janis Yanice 
Published: November 2020

AbstractThis paper describes the ethics of Christian religion teachers and their relevance to the faith of students using literature approach. The importance of the ethics for a Christian religion teacher is because being a Christian religion teacher is not just transferring knowledge, understanding and skills to students, but also educating students to experience a complete life transformation, especially experiencing a faith that is rooted, growing and fruitful in the Lord Jesus. To produce mature students in faith, Christian religious teachers must live the knowledge, understanding, and values of Christianity. This research is a qualitative research method with a literature study approach. From this research, it was found that the integration between teaching and living examples of a Christian religion teacher is an urgent matter and must be fulfilled because it is relevant to the faith education of the students.Keywords: Ethics; Christian religion teacher; faith education, student. AbstrakTulisan ini mendeskripsikan mengenai etika guru agama Kristen dan relevansinya terhadap pendidikan iman naradidik dengan menggunakan pendekatan literatur­. Pentingnya etika bagi seorang guru agama Kristen adalah karena menjadi guru agama Kristen bukan hanya sekadar mentransfer pengetahuan, pemahaman dan keterampilan terhadap naradidik, melainkan mendidik naradidik agar mengalami transformasi hidup secara utuh, khususnya mengalami iman yang berakar, bertumbuh dan berbuah di dalam Tuhan Yesus. Untuk mewujudkan naradidik yang dewasa dalam iman, maka guru agama Kristen harus menghidupi pengetahuan, pemahaman dan nilai-nilai agama Kristen. Penelitian ini merupakan metode penelitian kualitatif dengan pendekatan studi liteartur. Dari penelitian ini didapati bahwa integrasi antara pengajaran dan keteladanan hidup dari seorang guru agama Kristen menjadi hal yang mendesak dan sebuah keharusan untuk dipenuhi karena memiliki relevansi terhadap pendidikan iman naradidik.Kata Kunci: Etika; Guru Agama Kristen; Pendidikan Iman; Naradidik.
COVID-19 Mengubah Kehidupan Kita
Authors: Darwis Patrianef 
Published: November 2020

Sejawat sekalian, tahun 2020 adalah tahun yang berat bagi kita bersama. Bukan hanya bagi kita dibidang kesehatan, tetapi juga mengenai seluruh bidang kehidupan dan bukan hanya di Indonesia tetapi di seluruh dunia. Tantangan yang berat itu diakibatkan kemunculan virus COVID-19 yang mewabah di seluruh dunia.
Wabah COVID-19 ini di bidang kesehatan berpengaruh besar. Terjadi peningkatan kasus COVID-19 ini diseluruh dunia termasuk di Indonesia. Di Indonesia sendiri ada kesan awalnya pemerintah khususnya Kementerian Kesehatan sedikit gagap dan terkesan lambat dalam bertindak. Bahkan untuk proses diagnostik awalnya semua spesimen pemeriksaan swab tenggorokan dipusatkan di satu tempat sehingga untuk konfirmasi diagnosis memerlukan waktu yang lama sehingga proses konfirmasi diagnosis yang diperlukan untuk membatasi penyebaran penyakit dan proses pengobatan sedikit terhambat.
Di sisi lain kita sebagai dokter spesialis bedah yang melakukan pelayanan pasien terjadi perubahan besar. Proses pelayanan pasien termasuk pembedahan menyebabkan kita berkontak erat dengan pasien yang selama proses pelayanan bisa saja menderita COVID-19 dengan gejala ringan bahkan tanpa gejala. Demikian juga dokter lain yang tidak melakukan pembedahan. Angka kesakitan dan kematian dokter dan tenaga kesehatan lain meningkat dengan cepat. Angka kesakitan tersebut tinggi selain akibat faktor kontak juga akibat kekurang-siapan kita dalam penyediaan Alat Pelindung Diri (APD) yang diperlukan dalam perlindungan dokter dan tenaga kesehatan selama melayani pasien. Alhamdulillah, kekurangan APD tersebut pelan pelan dapat berkurang dan jumlah kesakitan dan kematian dokter serta tenaga kesehatan perlahan mulai menurun.
Sebagai dokter, proses pelayanan pasien yang memerlukan kontak erat dengan pasien menyebabkan kita rentan terkena COVID-19. Selain berpotensi terkena kita sendiri juga berpotensi menyebarkan COVID-19 di lingkungan keluarga kita bahkan kepada pasien lain. Untuk itu kita perlu taat dan patuh serta konsisten menggunakan APD yang tepat serta protokol kesehatan lain selama pelayanan pasien.
Kepada sejawat para dokter spesialis bedah, kita harus mengingat bahwa sebagai dokter, kita justru merupakan pihak yang rentan dan gampang tertular COVID-19. Untuk itu selama proses pelayanan pasien kita harus selalu menjaga jarak, mengenakan masker demikian juga selama di rumah kita harus menjaga keluarga kita dari penularan virus ini.
Mudah mudahan wabah COVID-19 ini cepat berlalu bukan hanya di Indonesia, tetapi diseluruh dunia sehingga kehidupan kita sebagai tenaga medis dapat kembali seperti sedia kala. Insyaallah
Accuracy of D-Dimer Levels and C-reactive Protein in Predicting Perforation of Acute Appendicitis
Authors: Lesmana Gema Putra , Rudiman Reno , Septrina Rani 
Published: November 2020

Introduction: D-Dimer as the primary product of fibrin degradation, was found to be increased in appendicitis patients. CRP still gives different results in predicting perforated appendicitis. The purpose of this study is to find out the accuracy of D-Dimer and CRP in predicting appendicitis perforation at the Central General Hospital Dr. Hasan Sadikin Bandung 2019.
Method: This study used prospective observational design with cross-sectional approach. The subject were taken from the Emergency Department (ED) patient between September 2018-September 2019 who met the inclusion criteria. Preoperative D-Dimer and CRP serum were measured and the results of the surgery were noted. Chi-Square test was conducted and the data were analyzed using SPSS Version 22.0 for windows at a 95% confidence level. The value is significant if p <0.05.
Results: The sample included in this study were 41 patients, with 24 perforated appendicitis patients. The average age of patients was 34.8 ± 13.8. The majority of patients were male, 24 patients ( 58.5%). Area for ROC curve for D-Dimer is 0.929, with a cut-off point of 0.51 mg / l for sensitivity perforation appendicitis 95.8%, specificity 76.5%, positive predictive value (PPV) 85.2%, negative predictive value (NPV) 92.9% and accuracy 87.8%. For CRP with a cut-off point at 18.84 for sensitivity perforation appendicitis 58.3%, specificity 94.1%, positive predictive value (PPV) 93.3%, negative predictive value (NPV) 61.5% with an accuracy of 73.2%.
Conclusion: D-dimer and CRP level can be used in predicting perforation of appendicitis.
(ISSN 2723-7494 J Bedah Indonesia. 2020;48:3-14)
A narrative study on work place based conflicts in obstetrics & gynecology department
Authors: Khadija Waheed  , Mohamed Al-Eraky  , Noor-i-kiran Naeem  , Sara Ejaz  , Amna Khanum  
Published: November 2020

Abstract
Objective: To explore the patterns in research and underlying factors of conflicts in obstetrics and gynaecology and its effect on restricting the quality of education and training of residents.
Methods: The narrative study was conducted at the Obstetrics and Gynaecology Department, Lady Aitchison Hospital, King Edward Medical University, Lahore, Pakistan, from October 2018 to January 2019, and comprised narrative essays by residents associated with the department. Data was subjected to thematic analysis.
Results: Of the 27 residents, 26(96.3%) were females and 1(3.7%) was male. Overall, 19(70.3%) were aged 25-30 years and 8(29.6%) were aged 30-35 years. Three levels of conflict were identified: organisational, interpersonal and individual. Causes of organisational conflict included inadequate facilities, poor security and unclear duty appointments. Interpersonal factors included lack of communication, lack of patient autonomy, non-cooperative co-workers, illiteracy of attendants and unprofessional behaviour. Individual factors were overburdening duty hours and duty negligence.
Continuous...
Educación Ambiental para el Desarrollo de Capacidades en Comunidades Rurales del Parque Nacional Pico de Orizaba
Authors: Landero-Hernández Lourdes , Chamorro-Zarate María de los Ángeles , Domínguez-González Nancy , Viveros-Contreras Rodolfo , Narave-Flores Venancio 
Published: November 2020

El Área Natural Protegida Parque Nacional Pico de Orizaba, tiene una superficie de 19, 750 ha, es la montaña con mayor altitud en México con 5, 636 msnm. Brinda valiosos servicios ambientales, es una importante área de captación para la recarga de acuíferos, mantiene la red hidrológica superficial de varias cuencas, abasteciendo de agua a más de un millón de personas resguardándolas además, ante fenómenos climáticos extremos. Conservar los bosques de coníferas y páramos de altura de esta zona, contribuye a conservar el único glaciar presente en la montaña. A pesar de ser importante por los servicios que provee, actualmente enfrenta diferentes problemáticas ambientales (caza de fauna silvestre, tala e incendios forestales, por mencionar algunos), que merman las acciones de conservación implementadas. La pérdida de biodiversidad debido principalmente a las actividades realizadas por las comunidades rurales con un alto grado de marginación que se encuentran colindantes, han afectado a especies de gran importancia. En el presente trabajo se aplicaron diferentes estrategias de Educación Ambiental como: capacitaciones, gestión de proyectos, vinculación con otros sectores y con otras comunidades, fortaleciendo las acciones de conservación. Las estrategias se implementaron en dos comunidades: Puerto Nacional en el municipio de Tlachichuca del estado de Puebla y Rancho Nuevo en el municipio de La Perla del estado de Veracruz. Se propició el desarrollo de capacidades de las comunidades, mediante la aplicación de cinco capacitaciones abordando diferentes temas y la creación de grupos de trabajo dando pauta a alternativas laborales que permitan la conservación de la diversidad biológica del parque.
The Use of Determinants of Length of Stay in the Post-anesthesia Care Unit (PACU) at the Philippine General Hospital among Postoperative Patients who Underwent Elective Surgeries to Create a Predictive Model for PACU Length of Stay
Authors: Aspi Maria Teresita B. , Ko-Villa Evangeline 
Published: November 2020

Background. The aims of this study were to determine the average length of stay in the Post-anesthesia CareUnit (PACU LOS) in the Philippine General Hospital (PGH) and to create a model that will predict the PACU LOSbased on the factors that significantly affect the LOS. Determination and prediction of PACU LOS is essential inresource utilization, and in cost containment and reduction. Addressing the modifiable variables that affect thePACU LOS may lead to an improvement in the LOS of patients in the PACU and, consequently, to better recoveryroom staffing and a reduced cost for the patients and the hospital.
Methods. A prospective chart review of 400 postoperative patients admitted in the PGH PACU was done. Summarystatistics were presented. Using the set of variables found to be significant, a regression model was formulatedto estimate the PACU LOS.
Results. The mean PACU LOS was 4.59 hours. There were significant differences in the mean PACU LOS basedon the occurrence of complications. There were also significant differences in the median PACU LOS based onthe type and duration of surgery, anesthetic technique, and duration of anesthesia. The multiple linear regressionmodel that best predicted PACU LOS included ASA-PS classification, type of surgery, duration of surgery, anesthetictechnique, and occurrence of intraoperative or postoperative complications.
Conclusions. The mean PACU LOS of the Philippine Genera Hospital is higher than that of published data. Thefactors included in the model that best predicts PACU LOS may be studied to improve the PACU LOS.
The Electronic Payment as an Effective Way to Improve the Electronic Government Services: Electronic "Tasdeed" Technology in Kuwait as a Model
Authors: Zouaouid Lazhari , Hajej Nafissa 
Published: November 2020

This study aimed to highlight the effectiveness of electronic payment in improving electronic government services, as an important tool that can raise the level of satisfaction of clients and businesses on the performance and quality of services by the government. The analytical descriptive approach was used in the study as the most appropriate to answer its problem, which is mainly focused on the contribution of the electronic payment method to improving e-government services, this topic was also dropped on the experience of the State of Kuwait through the project "Tasdeed" to push the government which represents the distinctive electronic payment of government fees and income through the provision of advanced electronic services to the government.
The study reached a set of results, most notably that the government electronic payment system "Tasdeed" in Kuwait is an ambitious model that contributed effectively to the embodiment and establishment of e-government by improving and improving the services.