bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histerectomía laparoscópica total en la unidad de endoscopia ginecológica de la Clínica del prado, Medellín (Colombia) 2002 - 2008
Authors: De Los Ríos José F. , Castañeda Juan D. , Calle Gustavo A. , Serna Eduardo , Vásquez Ricardo A. , Arango Adriana M. , Flórez Orlando J. , Mejía Ana M. , Arango Victoria , Palacio Tatiana 
Published: February 2020

Objetivo: describir la experiencia en la práctica de Histerectomía Laparoscópica Total (HLT) con énfasis en las complicaciones presentadas.Metodología: el presente es un estudio de cohorte histórica en el cual se incluyeron las pacientes que fueron intervenidas entre diciembre de 2002 y abril de 2008 y en quienes, además, se completó al menos 90% de la información requerida en un formulario prediseñado. Durante la investigación, se evaluaron las características sociodemográficas, las indicaciones de cirugía, el porcentaje de laparoconversión y las causas de la misma, el tiempo quirúrgico, la pérdida sanguínea estimada, el tiempo de hospitalización, el número de dosis de analgésicos requeridos, los días de incapacidad y las complicaciones intraoperatorias y postoperatorias.Resultados: en total se incluyeron 837 pacientes, cuya edad promedio fue 42,7 años. 83,8% de las mujeres eran ASA I (American Society of Anesthesiologists) y la principal enfermedad de base fue la hipertensión arterial (9,9%). En 822 de ellas, el procedimiento se llevó a cabo por laparoscopia mientras que 15 (1,7%) requirieron laparoconversión. Las indicaciones más frecuentes para la cirugía fueron miomatosis (43,8%) y hemorragia uterina anormal (36,1%). Adicional a esto, el tiempo quirúrgico promedio fue 85,9 minutos, la pérdida sanguínea media fue de 60,6 mL y la tasa total decomplicaciones llegó a ser 12,5%; de lacuales,3,1% lo constituyeron complicaciones mayores.Conclusiones: la tasa de complicaciones de la histerectomía laparoscópica total es similar a la informada en la literatura y está acompañada de una estancia hospitalaria breve.
Mutu Pendidikan Sekolah Dasar di Kabupaten Kutai Timur
Authors: Hasanah Siti Nur 
Published: February 2020

This research is motivated by the quality of education in East Kutai District. It was not equally between infrastructure and suprastructure school developments in the rural and the urban areas. It also can be effect to the quality of educations in East Kutai District, especially in rural areas. The aims of this research are describes the quality condition of elementary schools in East Kutai District, discribes supporting factors and obstacle factors, and the efforts of goverment (ministry of education) to improve the quality education of elementary schools in East Kutai District.This is descriptive qualitative research. It was located in education goverment office (ministry of education).The result of this research was indicated that the quality education of elementary school in East Kutai Distric is excellent. It shows from the increase accreditation result every year. At 2016 all of elementary schools in East Kutai District was accredited. It was good progress. Eight national education standarts have been achieved. The supporting factors to increase the quality education of elementary school in East Kutai District, such us: qualified human resources, a lot of budget funds, between elementary schools and ministry of education has been mutual support, good infrastructure development, and good geographic location. Even while obstacle factors such us: small budget funds, the school locations are so far from the town, education policies always change every a new minister education, and different understanding about education mindset. The efforts from education department goverment (ministry of education) to improve the quality education of elementary school in East Kutai District are: complete the database, reorganized institution, change mindset the teachers from teachers become educators, make a program training and coaching, adjusting teacher qualifications, make a program one sub district one favorite school, make a curriculum development, strengthening of character education, make a programe one student one book of curriculum 2013, make a mapping and dissemination for all teachers, rolling teachers and head master, make a program rehabilitation of all facilities and infrastructure, do controling from UPT.
The Method of Sources and Sinks—A Perspective
Authors: Raghavan Rajagopal 
Published: February 2020

Abstract
Professor Henry J. Ramey once remarked that he wished he had devoted more time to the study of recovery problems but that the intellectual challenges of issues in well-test analysis were much too enticing. Among his myriad interests, the method of sources and sinks had a special place. Undoubtedly, his early work in thermal recovery1 served as a spark for his "deep affection" for the method of sources and sinks. This communication is a bird's-eye-view of this subject as it pertains to well-test analysis. I hope that this note will spark an interest in this topic for those unfamiliar with this method of solving partial differential equations and at the same time provide additional insights to those familiar with this topic. The examples considered here have been chosen with two perspectives. First, given the nature of this contribution, they serve a historical purpose. Second, they address some issues that need to be highlighted.
A New Material for Deep Well Cementing
Authors: Smith Dwight K. 
Published: February 2020

Published in Petroleum Transactions, Volume 207, 1956, pages 59–64.

Abstract
A new pozzolanic composition has been developed for cementing oil wells where moderate to high temperatures prevail. This material is an entirely different concept to other oil well cementing materials, such as portland cements, cements containing additives, or liquid resins. Its characteristics are such that it is not, at present, recommended for use at temperatures less than 140°F. It can be either accelerated or retarded across a wide range of well conditions.
This new cement is composed of a pozzolanic material, hydrated lime, and a chemical activator to give it early initial strength. This material can be used in wells from 6,000 to 18,000 or more feet where temperature conditions are similar to those along the Gulf Coast. This cement, when set, has no soluble portion subject to leaching or any compounds that should be attacked by sulfate waters or brines. For this reason, it should be permanent when placed adjacent to formations carrying any type of fluid.
The compressive strengths in 24 hours are more than adequate for wells where temperatures are 140°F and higher. These values are in excess of many other types of cementing composition presently in use in the field. This pozzolanic composition does not retrogress in strength at high temperatures as do some other types of cementing materials.
The slurry weights of this material will vary slightly according to the specific gravity and water requirements of the pozzolan itself. The materials covered herein will mix from 13.5 to 14.3 lb/gal, and will have a waiting-on-cement time comparable to other materials used under the same conditions.
Economically speaking, this composition is less expensive than either portland cements or retarded cements presently being used under deep well conditions.

Introduction
Pozzolans are "siliceous material which, though not cementitious in themselves, contain constituents which at ordinary temperatures will combine with lime in the presence of water to form compounds which have a low solubility and possess cementing properties." The use of pozzolanic materials dates back many hundreds of years and both the ancient Greeks and Romans were aware that certain volcanic deposits, if finely ground and mixed with lime and sand, yielded a mortar which possessed special properties. Generally, the early strengths of such materials were rather weak and were considered insufficient for modern commercial usages.
Effect of Clay and Water Salinity on Electrochemical Behavior of Reservoir Rocks
Authors: Hill H.J. , Milburn J.D. 
Published: February 2020

Published in Petroleum Transactions, Volume 207, 1956, pages 65–72.

Abstract
In quantitative interpretation of electrical logs the presence of clay minerals introduces an additional variable which further complicates an already complex problem. Although recognizing the difficulties introduced as a result of the heterogeneity of natural sediments and despite the present incomplete state of knowledge regarding electrochemical behavior of shades, disseminated clay minerals and concentrated electrolytes, it was felt that useful empirical correlations might be obtained from experimental investigation.
Six typical sandstone formations, having a wide variety of petrophysical properties, were selected for the study. Approximately 45 samples from each formation were selected to satisfactorily represent the range of pore size distribution within the particular formation. As a matter of general interest, four limestone formations were also included in the investigation.
Previously proposed equations relating to resistivity, SP and interrelationship of the two phenomena have, where possible, been tested with data obtained in this investigation. These equations do not satisfactorily describe experimental behavior of samples through all degrees of shaliness or throughout the range of brine solution resistivities normally encountered in logging practice.
An empirical equation has been developed which quantitatively relates formation resistivity factor to saturating solution resistivity, porosity, and "effective clay content." This relation is indicated to be uniformly applicable to clean or shaly reservoir rocks.
It is shown that both the SP and resistivity phenomena of shaly samples are related to the sample cation exchange capacity per unit pore volume. The independent chemical determination of this parameter is thus a means of determining the "effective clay content" of samples.
Some implications regarding theory and electric log interpretation of shaly sands are discussed.

Introduction
The use of electrical resistivity logs as a means for estimating formation porosity is based upon the original work of Archie.
Identification of NHXs in Gossypium species and the positive role of GhNHX1 in salt tolerance
Authors: Long Lu , Zhao Jing-Ruo , Guo Dan-dan , Ma Xiao-Nan , Xu Fu-Chun , Yang Wen-Wen , Gao Wei 
Published: March 2020

Abstract
Background: Plant Na+/H+ antiporters (NHXs) are membrane-localized proteins that maintain cellular Na+/K+ and pH homeostasis. Considerable evidence highlighted the critical roles of NHX family in plant development and salt response; however, NHXs in cotton are rarely studied.Results: The comprehensive and systematic comparative study of NHXs in three Gossypium species was performed. We identified 12, 12, and 23 putative NHX proteins from G. arboreum, G. raimondii, and G. hirsutum, respectively. Phylogenetic study revealed that repeated polyploidization of Gossypium spp. contributed to the expansion of NHX family. Gene structure analysis showed that cotton NHXs contain many introns, which will lead to alternative splicing and help plants to adapt to high salt concentrations in soil. The expression changes of NHXs indicate the possible differences in the roles of distinct NHXs in salt response. GhNHX1 was proved to be located in the vacuolar system and intensively induced by salt stress in cotton. Silencing of GhNHX1 resulted in enhanced sensitivity of cotton seedlings to high salt concentrations, which suggests that GhNHX1 positively regulates cotton tolerance to salt stress.Conclusion: We characterized the gene structure, phylogenetic relationship, chromosomal location, and expression pattern of NHX genes from G. arboreum, G. raimondii, and G. hirsutum. Our findings indicated that the cotton NHX genes are regulated meticulously and differently at the transcription level with possible alternative splicing. The tolerance of plants to salt stress may rely on the expression level of a particular NHX, rather than the number of NHXs in the genome. This study could provide significant insights into the function of plant NHXs, as well as propose promising candidate genes for breeding salt-resistant cotton cultivars.
Birth outcomes in a Swedish population of women reporting a history of violence including domestic violence during pregnancy: A longitudinal cohort study
Authors: Finnbogadóttir Hafrún , Baird Kathleen , Thies-Lagergren Li 
Published: March 2020

Abstract
Background: Victimisation of women is encountered in all countries across the world, it damages the mental and physical health of women. During pregnancy and the postpartum period, women are at a greater risk of experiencing violence from an intimate partner. The aim of this study was to explore childbirth outcomes in a Swedish population of women reporting a history of violence including domestic violence during pregnancy.
Methods: A longitudinal cohort design was used. In total, 1939 pregnant women ≥ 18 years were recruited to answer two questionnaires, both questionnaires were administered in the early and late stages of their pregnancy. The available dataset included birth records of 1694 mothers who gave birth between June 2012 and April 2014. Statistical analyses included descriptive statistics, T-test and bivariate logistic regression. Results: Of 1694 mothers 38.7 % (n = 656) reported a history of violence and 2% (n = 34) also experienced domestic violence during pregnancy. Women who were single, living apart from their partner, unemployed, smoked and faced financial distress were at a higher risk of experiencing violence (p = 0.001). They also had significant low scores on the SOC-scale and high EDS-scores ≥ 13 (p =0.001) when compared to women without a history of violence (p = 0.001). Having a history of violence increased the woman’s risk of undergoing a caesarean section (OR 1.33, 95 % CI 1.02 -1.70). A history of emotional abuse also significantly increased the risk of having a caesarean section irrespective of whether it was a planned or an emergency caesarean section (OR 1.50, 95% CI 1.09-2.06). Infants born to a mother who reported a history of violence, were at significant risk of being born premature < 37 weeks of gestation compared to infants born by mothers with no history of violence (p = 0,049). Conclusions: A history of violence and/or exclusively a history of emotional abuse has a negative impact on childbirth outcomes including caesarean section and premature birth. Therefore, early identification of a history of or ongoing violence is crucial to provide women with extra support which may have positive impact on her birth outcomes.
Analysis of the causes of cervical lymphadenopathy using Fine-Needle Aspiration Cytology combining cell block in Chinese Patients with and without HIV infection
Authors: Sun Lei , Zhang Liang , Yang Kun , Chen Xiang-mei , Chen Jia-min , Xiao Jiang , Zhao Hong-xin , Ma Zhi-yuan , Qi Li-ming , Wang Peng 
Published: March 2020

Abstract
Background

Cervical lymphadenopathy refers to a frequently observed clinical presentation in numerous pathological conditions. A wide spectrum of diseases can cause cervical lymphadenopathy, irrespective of the fact that the patients are infected with HIV or not. The present study focuses on validating whether the causes of cervical lymphadenopathy differ significantly in HIV and non-HIV patients by using fine-needle aspiration cytology (FNAC) combining cell block.

Methods

A total of 589 patients with cervical lymphadenopathy were recruited in the FNA clinic. The samples were obtained by an auto-vacuumed syringe that benefited the sampling more materials. The cytological smears were prepared by Hematoxylin and Eosin (HE), Periodic Acid Schiff (PAS), Gomori’s methenamine silver (GMS) and acid-fast staining. Cell blocks were made if required, and immunohistochemistry stain was performed on the cell block section.

Results

The study found 453 (76.9%) patients with HIV and 136 (23.1%) patients without HIV infection. The average age of HIV-infected patients was 34.8 ±10.2 years, which was significantly lower than that of non-HIV-infected patients (42.9 ±18.1 years) (p<0.01). Of all patients infected with HIV, 390 (86.1%) were males. This proportion was significantly higher than that of non-HIV-infected patients [65/136 (47.8%)] (p<0.01). The major causes of cervical lymphadenopathy in HIV positive patients were mycobacterial infection (38.4%), reactive hyperplasia (28.9%), non-specific inflammation (19.9%), and malignant lesions (4.2%). In contrast, the most common causes in HIV negative patients were reactive hyperplasia (37.5%), malignancy (20.6%), non-specific inflammation (19.1%) and mycobacterial infection (12.5%). Opportunistic infections such as non-tuberculous mycobacteria (4.2%), cryptococcosis (1.5%), Talaromyces marneffei (1.5%) and other fungi (0.4%) were found only in HIV-infected individuals. Non-Hodgkin’s lymphoma (2.4%) was the most common malignant lesion in patients with HIV infection, followed by Kaposi's sarcoma (0.9%) and metastatic squamous cell carcinomas (0.7%). However, the most common malignancy in non-HIV-infected patients was metastatic carcinomas (14%) including small cell carcinomas, adenocarcinomas, squamous cell carcinomas and hepatocellular carcinoma, which were noticeably greater than the HIV patients (p<0.01).

Conclusions

There were significantly different causes of cervical lymphadenopathy in HIV infected and non-HIV infected patients. FNAC was a useful diagnostic method for differential diagnosis of cervical lymphadenopathy.
Identifying Phenogroups in Patients with Subclinical Diastolic Dysfunction Using Unsupervised Statistical Learning
Authors: Kaptein Yvonne E. , Karagodin Ilya , Zuo Hongquan , Lu Yu , Zhang Jun , Kaptein John S. , Strande Jennifer 
Published: March 2020

Abstract
Background Subclinical dysfunction is a precursor for developing heart failure with preserved ejection fraction (HFpEF); yet not all patients progress to HFpEF. Our objective was to evaluate clinical and echocardiographic variables to identify patients who develop HFpEF. Methods Clinical, laboratory, and echocardiographic data were retrospectively collected for 81 patients without HF and 81 matched patients with HFpEF at the time of first documentation of subclinical diastolic dysfunction. Density-based clustering or hierarchical clustering to group patients based on 65 total variables including 19 categorical and 46 numerical variables. Logistic regression analysis was conducted on the entire study population as well as each individual cluster to identify independent predictors of HFPEF. Results Unsupervised clustering identified 3 subgroups which differed in gender composition, severity of cardiac hypertrophy and aortic stenosis, NT-proBNP, percentage of patients who progressed to HFpEF, and timing of disease progression from diastolic dysfunction to HFpEF to death. Clusters that had higher percentages of women had progressively milder cardiac hypertrophy, less severe aortic stenosis, lower NT-proBNP, were diagnosed at an older age with HFpEF, and survived to an older age. Independent predictors of HFpEF for the entire cohort included diabetes, chronic kidney disease, atrial fibrillation, and diuretic use, with additional predictive variables found for each cluster. Conclusions Cluster analysis can identify phenotypically distinct subgroups of patients with diastolic dysfunction. Clusters differ in HFpEF and mortality outcome. In addition, the variables that correlate with and predict HFpEF outcome differ among clusters.
Maple Syrup Urine Disease in Brazilian Patients: Variants and Clinical Phenotype Heterogeneity
Authors: Margutti Ana Vitoria Barban , Silva Wilson Araújo , Garcia Daniel Fantozzi , de Molfetta Greice Andreotti , Marques Adriana Aparecida , Amorim Tatiana , Prazeres Vânia Mesquita Gadelha , Silva Raquel Tavares Boy da , Miura Irene Kazue , Neto João Seda , Santos Emerson de Santana , Santos Mara Lúcia Schmitz Ferreira , Lourenço Charles Marques , Tonon Tássia , Sperb-Ludwig Fernanda , de Souza Carolina Fischinger Moura , Schwartz Ida Vanessa Döederlein , Junior José Simon Camelo 
Published: March 2020

Abstract
Background: Maple syrup urine disease (MSUD) is an autosomal recessive inherited metabolic disease caused by deficient activity of the branched-chain α-keto acid dehydrogenase (BCKD) enzymatic complex. BCKD is a mitochondrial complex encoded by BCKDHA , BCKDHB , DBT , and DLD genes. MSUD is predominantly caused by Variants in BCKDHA , BCKDHB , and DBT genes encoding the E1α, E1β, and E2 subunits of BCKD complex, respectively. The aim of this study was to characterize the genetic basis of MSUD by identifying the point variants in BCKDHA , BCKDHB , and DBT genes in a cohort of Brazilian MSUD patients and to describe their phenotypic heterogeneity. It is a descriptive cross-sectional study with 21 MSUD patients involving PCR and sequencing. Results: Nine new variants predicted as pathogenic were found between 30 variants identified in the 21 patients analyzed: two in the BCKDHA gene (p.Gly56Arg, and p.Tyr120Ter); five in the BCKDHB gene (p.Gly131Val, p.Glu146Glnfs*13, p.Phe149Cysfs*9, p.Cys207Phe, and p.Lys211Asn); and two in the DBT gene (p.Glu148Ter and p.Glu417Val). Seventeen pathogenic variants were previously described and four variants showed no pathogenicity according to in silico analysis. Conclusion: Given that most of the patients received late diagnoses, the study results do not allow us to state that the molecular features of MSUD variant phenotypes are predictive of clinical severity. Keywords: inborn errors of metabolism; maple syrup urine disease; branched-chain amino acids; valine; leucine; isoleucine.
The Adoption Level of Electronic Health Records in Turkish Hospitals and the Relation with Hospital Sizes
Authors: Kose Ilker , Rayner John , Birinci Suayip , Ulgu Mustafa Mahir , Yilmaz Ismayil , Guner Seyma 
Published: March 2020

Abstract
Background: Considering the benefits of using electronic health records (EHR) for maintaining the overall quality of clinical care, the nationwide adoption of EHR in hospitals has become a policy priority. The electronic medical record maturity model (EMRAM) is one of the most popular survey tools developed by the Healthcare Information and Management Systems Society (HIMSS) that measures the level of adoption for EHR functions in a hospital or a secondary care setting. Turkey has accomplished many standardizations and infrastructural studies in the health IT domain as a part of the first phase of the Health Transformation Program between 2003 and 2017. The Turkish MoH applied a bottom-up approach to adopting EHR in public hospitals, as the USA did. This study aims to measure the EHR adoption level of public hospitals in Turkey and criticize the relation between adoption and hospital size. Methods: EMRAM surveys were completed by 600 (68.9%) public hospitals of Turkey between 2014 and 2017. The availability and prevalence of medical information systems and EHR functions were measured. The association between hospital size and the availability/prevalence of EHR functions was also calculated. Results: We found that 63.1% of all hospitals in Turkey have at least basic EHR functions, and 36% have comprehensive EHR functions, which is better than the results of Korean hospitals of 2017 but still lower than the USA hospitals of 2015 and 2017. Our findings suggest that small hospitals are better than larger hospitals at adopting certain EHR functions. Conclusion: Measuring the overall adoption level of EHR functions is an emerging approach and a beneficial tool for the strategic management of countries. This study is the first one covering all public hospitals in a country by using EMRAM. It can be suggested that using a bottom-up approach as applied by the USA on adopting EHR in public hospital gives successful results also in Turkey. The results are used by MoH of Turkey to disseminate the benefits of EHR functions overall in the country.