bluuebunny/crossref_metadata_2025_split huggingface dataset:
STEVENS JOHNSON SYNDROME PADA PASIEN HIV
Authors: Citra Bevi Dewi , Masri Raveinal 
Published: May 2020

<p><em>Stevens Johnson Syndrome (SJS) are form of drugs hypersensitivity reaction with high morbidity besides Toxic Epidermal Necrolysis (TEN). HIV-patients are one of the population with higher risk. Its due to, in this population had multifactorial aspects and related with drug metabolism, dysregulation of the immune systems (immune hyperactivation, patients cytokine profile and CD4 cell count),</em> <em>oxidative stress, genetic predisposition,and viral factors. A case of female, 42 years old, who had been known as HIV patients with clinical stage 3 had Stevens Johnson Syndrome. Allegedly, it caused by antiretroviral drugs (nevirapine), which she consumed for 3 weeks. Patient also has fever and hepatitis drug induced. For the the treatment, we stopped previous combination of antiretroviral drugs immediately and replaced by another combination. Furthermore, patient also had corticosteroid therapy and others supportive treatments, such as intra venous fluid, adequate nutrition, antibiotic, antifungal and also had eyelid, oral, nose and skin treatment. Patient showed clinical improvements and and improvement of liver function test after received treatments for one week in hospital </em></p><p><strong><em>Keywords: </em></strong><em>Stevens Johnson Syndrome, HIV, antiretroviral</em><em></em></p>
Microflares and nanoflares in the solar corona
Authors: Bogachev S A , Ulyanov A S , Kirichenko A S , Loboda I P , Reva A A 
Published: May 2020

Abstract

Due to the increase in the spatial and temporal resolution of observations of the solar atmosphere, which is mainly associated with progress in space research, we now understand that the Sun’s activity not only is associated with large centers, but also extends to significantly smaller scales. Each new advance in experimental technology over the past 60 years has led to the discovery of more and more numerous and small solar structures: X-ray active regions in the 1960s, hot X-ray points in the 1970s, solar microflares in the 1980s, and finally, from the end of the 20th century, solar nanoflares. At the same time, the total energy release, obtainable from observations, is still insufficient to ensure a balance between heating of the corona and its rapid radiative cooling. For the smallest-scale phenomena, nanoflares, it is still not possible to resolve their structure and mechanism, which raises the question of whether it is correct to classify them as flares. We present a review of the main results obtained so far in the field of small-scale solar activity, mainly microflares and nanoflares, and discuss the main issues that need to be solved in order to move forward.
Wigner’s friend paradox: does objective reality not exist?
Authors: Belinsky A V 
Published: May 2020

Abstract
It is shown that the lack of objective existence of the results of quantum measurements of the state of collapse of the state vector of a remote localized system cannot be proved by an experiment using the reality of violation of Bell’s inequality in the Clauser–Horne–Shimony–Holt form. Arguments of a general nature and a specific calculation example confirming this conclusion are also given.
ANALISIS KAUSAL MASA STUDI MAHASISWA PROGRAM STUDI MATEMATIKA UNIVERSITAS ANDALAS DENGAN MENGGUNAKAN METODE CART
Authors: Izzati Rahmi  , Hazmira Yozza  
Published: May 2020

To provide a quality and sustainable education, each study program needs to evaluate the effectiveness and productivity of education, one of which is using indicator of the length of the study. The length of study is influenced by various factors. In this study observations and evaluations of the factors affecting the study period of students of Study Program of Mathematics at Andalas University were conducted by using CART (Classification and Regression Tree) method. The results showed that the most significant factor influencing the length of the study is the Grade Point Average (GPA). Students with high GPA will have a higher chance of graduating on time. Another factor influencing the length of the study is student achievement during high school. Students who consistently perform well (always get the highest rank) when in high school have a high chance of graduating on time. The analysis also showed that students who joined the organization while in high school had a higher chance of graduating on time than those who did not participate. The interesting thing is the students who choose the Study Program of Mathematics at Andalas University as the third choice had a higher chance of graduating on time than the students who choose it as the first or second choice.
Dalam upaya menyelenggarakan pendidikan yang berkualitas dan berkesinambungan, maka setiap program studi perlu melakukan evaluasi terhadap efektifitas dan produktivitas pendidikan, salah satunya dengan menggunakan indikator masa studi. Masa studi mahasiswa dipengaruhi oleh berbagai faktor. Dalam penelitian ini dilakukan analisis terhadap faktor-faktor yang mempengaruhi masa studi mahasiswa Program Studi Matematika Universitas Andalas dengan menggunakan metode CART. Hasil penelitian menunjukkan bahwa faktor yang paling signifikan mempengaruhi masa studi mahasiswa adalah Indeks Prestasi Kumulatif (IPK). Mahasiswa dengan IPK tinggi akan mempunyai peluang lulus tepat waktu lebih tinggi. Faktor lain yang berpengaruh adalah prestasi mahasiswa sewaktu SMA. Mahasiswa yang konsisten berprestasi baik (selalu juara) ketika SMA mempunyai peluang yang tinggi untuk lulus tepat waktu. Hasil analisis juga menunjukkan bahwa mahasiswa yang mengikuti organisasik etika SMA mempunyai peluang lulus tepat lebih tinggi dibandingkan yang tidak ikut organisasi. Suatu hal yang cukup menarik adalah berdasarkan urutan pilihan ketika memasuki perguruan tinngi, kelompok mahasiswa yang memilih Program Studi Matematika Universitas Andalas sebagai pilihan ketiga justru memiliki peluang lulus tepat waktu yang lebih tinggi dibandingkan kelompok mahasiswa yang memilih matematika sebagai pilihan pertama atau kedua.
Assessment of antibacterial effectiveness of ultrasonic scaling in combination with calcium hydroxyappatite suspension among patients with type-1 diabetes
Authors: Orekhova L. Yu. , Musaeva R. S. , Loboda E. S. , Grinenko E. V. , Vorobyeva N. V. , Shumilina E. D. 
Published: May 2020

Relevance. Type-1 diabetes mellitus affects usual oral microbiome for active growth of periodontal pathogenic bacteria concentration in geometric progression, which leads to decrease in function of local immunity of oral cavity, inflammation of periodontal tissues and resorption of alveolar bone – the characteristics of chronic generalized periodontitis. This article provides analysis of qualitative and quantitative composition of microflora of periodontal pocket among type-1 diabetes patients before and after conservative periodontal therapy using ultrasonic treatment technique with a polishing suspension based on calcium hydroxide («Vector Paro», Durr Dental).Purpose. To evaluate the antibacterial effectiveness of professional oral hygiene complex with the additional treatment of periodontal pockets with «Vector Paro» device among patients with type-1 diabetes and chronic generalized mild periodontitis.Materials and methods. 30 patients with chronic generalized mild periodontitis and type-1 diabetes were examined with using analyses of periodontal pockets microflora contents. All patients underwent a standard complex of professional oral hygiene and gentle periodontal therapy with the «Vector Paro» device. Re-examination was in 4 weeks.Results. The performed complex of conservative periodontal therapy improved periodontal status in both groups, but in control group changes were more significant.Conclusion. Dynamic monitoring of qualitative and quantitative composition of periodontal pockets in combination with conservative periodontal therapy using the «Vector Paro» apparatus improves hygienic and periodontal status among patients with type-1 diabetes.
Comparative assessment of average clinical smile parameters in male and female patients with orthognathic occlusion
Authors: Galonsky V. G. , Tarasova N. V. , Aliamovskii V. V. , Leonovich I. S. 
Published: May 2020

Relevance. Separate issues in anthropomorphic sizes of relative norm of the ideal smile, its qualitative and qualitative parameters have not been addressed to sufficiently and are not properly reflected in scientific literature.Purpose. To determine distinguishing features in average smile parameters of the smile in male and female patients with orthognathic occlusion.Materials and methods. A clinical and anthropometric evaluation of parameters in main smile types was carried out for 150 young males and 150 young females aged 19-24 who had identical physiological development parameters.Results. It has been revealed that occurrence frequency of main smile types in patients with orthognathic occlusion has pronounced signs of sexual dimorphism which in over one half of the cases lies in predominance of the incisal smile type in males (52.7%) and the fascial type in females (55.3%). Occurence frequency of the cervical smile type totaled 25% among the studied patients of both genders. Average vertical size parameters in the incisal smile lies within the diapason of 3.91-4.91mm with surpassing by 1mm in males. Analogical data for the fascial smile type form the diapason of 6.21-6.73mm with surpassing by 0.52mm in females. The cervical smile type is characterised by larger vertical size forming the diapason of 7.94-8.91mm with surpassing by 0.97mm in males.Conclusion. The results of the study have shown that the “beautiful and ideal smile” is a relative concept having varied anthropometric characteristics and pronounced signs of sexual dimorphism lying in a broad spectrum of the dentofacial system norm notion with specific vectors for individual morphological deviations.
Decompensated (compromised) dentition (philosophical essay)
Authors: Trezubov V. N. , Rozov R. A. 
Published: May 2020

Relevance. In our clinical practice we’ve noticed a substantial amount of patients seeking prosthodontic treatment with the situation where all the teeth in dental arches (maxilla or mandible) have to be extracted due to distrophic, degenerative periodontal conditions. We started to define this condition as “decompensated dental arch” (compromised dentition). However, there is no information on treatment tactics in such patients.Purpose. To develop medical tactics in the dental treatment of patients with decompensated dental arches.Materials and methods. We examined 211 patients (74 males, 134 females) aged from 54 to 83 years old (mean age: 72.4 ± 6.3) with 275 decompensated (compromised) upper (73) and lower (202) dental arches. We used clinical and paraclinical (additional) diagnostic methods such as ultrasound, Doppler, electromyography, CT scan, OPG evaluation.Results. Comprehensive description of “decompensated dentition” (compromised)lead us to implementation of radical treatment approach during preparation for prosthodontic rehabilitation. First of all that approach facilitates quick transition from handicapped condition to the high quality of life in case of applying principals of immediate (including implant supported) prosthetics. Clinical experience proves that “Merciful” (tooth saving) tactics with the attempt to relative saving of some teeth with conservative approach will prolong the agony of decompensated dentition (compromised) especially in case of treating elderly patients with compromised medical condition. Radical approach helps to get long term survival of implants and prostheses.Conclusion. That’s the reason that in cases of clinical situation of decompensated dentition (compromised) we have to focus on more radical preparation to prosthodontic -especially implant supported – rehabilitation.
Epulises: current problem
Authors: Burdina P. A. , Turin A. G. 
Published: May 2020

Relevance. Nowadays an important problem in dentistry is the early diagnosis and the treatment of tumors and tumor-like lesions. One of the most frequent lesions of the orofacial region, and particularly of the periodontium, is a non-tumor lesion called epulis. Some tumors and tumor-like lesions may be both clinically and histologically similar, hence the diagnosis and the differential diagnosis of the epulis is still complicated and need to pay attention. Moreover, every type of epulis has particular histological features that make a clinician use a specific treatment in each clinical case. The treatment success and the necessity of the further observations are determined by the correct diagnosis. However, there is still controversial data about epulis diagnosis. Moreover, the reliable criteria for correct diagnosis of each type of epulis have not been discussed yet.Purpose. The aim of this study is to determine the most relevant methods for differential diagnosis of every type of epulis and other tumor and tumor-like lesions of the alveolar ridge with the same clinical and histological descriptions was performed.Materials and methods. In this article the review of the literature is presented. A comprehensive literature search of the studies from 1970 through 2019 in PubMed database regarding the epulis and other tumor and tumor-like lesions with the same clinical and histological descriptions was performed. 71 relevant articles were selected.Results. “Epulis” is a term that refers to tumor and tumor-like lesions of the alveolar ridge. Due to their morphological features it is frequently necessary to carry out not only the histological studies but also use immunohistochemical and genetic analyses. It is not complicated to verify vascular epulis and fibrous epulis. If there is a plasma-cell infiltration of fibrous epulis stroma, clinician is to differ it from IgG4-assosiated diseases. In some cases to discern pyogenic granuloma and hemangioma it is necessary to carry out immunohistochemical study of the blood vessel wall components. It is also important to know diagnostics of giant-cell epulis. Here to divide peripheral and central giant-cell granulomas genetic analysis should be carried out.Conclusion. Usually microscopic study of fibrous and vascular epulis helps to differentiate it with other lesions. The IgG4associated diseases are to exclude by immunohistochemical study. Diagnostics of giant-cell epulis may include both immunochemical and genetic studies. Methods presented in this article are important both for treatment and for prognosis of the disease.
The impact of the viral-bacterial consortium on occurrence and development of chronic periodontitis
Authors: Tsarev V. N. , Yagodina E. A. , Tsareva T. V. , Nikolaeva E. N. 
Published: May 2020

Relevance. The current theory of specific bacterial biofilm fails explain why a part of patients experiences inflammatory periodontal diseases while the absence of detected specific types of “red complex” bacteria.Purpose. To clarify the microbiological and immunological mechanisms of the influence of the viral and bacterial consortium in the etiology and pathogenesis of inflammatory periodontal diseases.Materials and methods. Articles survey with elements of metanalisis. Literature review based on discussion of research results on the topic of 48 sources including 33 foreign ones.Results. The review provides evidences of the possible participation of viruses of the Herpesviridae family in the development of chronic generalized periodontitis. Evidences for the role of herpes simplex viruses of type 1.2, Epstein-Barr virus, and cytomegalovirus in the development of periodontal inflammation are analyzed. It is proven that all herpesviruses induce the release of proinflammatory cytokines that activate osteoclasts and matrix metalloproteinases, as well as violate antibacterial immune mechanisms. In turn that leads to a progressive increase of periodontal pathogenic bacteria in both the biofilm and periodontal tissues.Conclusion. It is made a conclusion that an active herpetic infection can initiate damage to periodontal tissus and participate in the development of relapses of the disease.
Complex treatment of periodontitis: patient’s reaction to the therapy
Authors: Iordanishvili A. K. , Guk V. A. , Golovko A. A. 
Published: May 2020

Relevance. The success of treatment of periodontal diseases directly depends on the patient’s response to the therapy, therefore, the characteristics of the person’s personal characteristics can affect both the effectiveness of treatment and the prevention of relapse of the disease.Purpose. To study the features of the internal picture of the disease in the process of complex treatment of adult patients suffering from chronic generalized periodontitis.Materials and methods. The generally accepted comprehensive treatment of chronic generalized periodontitis in 69 middle-aged and elderly men was carried out taking into account the personal response of patients Solovyov «Psychosensory-anatomical-functional maladaptation syndrome».Results. When patients were discharged from the hospital, there was a difference in the phenomena of maladaptation among the elderly and middle-aged: in middle-aged people, sufficient adaptation to the conditions of existence was determined; in elderly people, due to the existing comorbid pathology, a state of maladaptation was diagnosed, which was caused by the presence of complaints of defects in the dentition.Conclusion. In elderly people, as soon as possible after completion of treatment in a hospital, dental rehabilitation cannot be considered completed, which requires the adoption of organizational measures for their timely provision of dentures.
YAŞLILARIN HASTANE FİZİKSEL ORTAMINA BAĞLI YAŞADIĞI SORUNLAR VE ETKİLEYEN FAKTÖRLER / THE PROBLEMS AND FACTORS THAT EFFECT THE ELDERLY RELATED TO THE HOSPITAL PHYSICAL ENVIRONMENT
Authors: Kılıç Mahmut , Uslukılıç Güllü 
Published: May 2020

Amaç: Bu çalışmada, yaşlı bireyin hastanenin fiziksel ortamına bağlı yaşanan sorunlar ve yaşam kalitesiyle birlikte etkileyen faktörleri tespit etmektir.
Gereç ve Yöntem: Araştırma kesitsel tipte olup, 2019 yılında üniversite araştırma hastanesi ile şehir hastanesine başvuran 65 yaş ve üstü yaşlılar arasında yapılmıştır. Araştırmaya 400 yaşlı alınmıştır. Veriler, sosyo-demografik veri formu, yaşam kalitesi kısa formu (SF12) ve hastane içi ve çevresi fiziki düzenlemelerin uygunluğunu belirleyen anket formu aracılığıyla elde edilmiştir. Anketler, araştırmacı tarafından görüşmeci aracılığıyla doldurulmuştur. Veriler SPSS programı ile değerlendirilmiştir. Yeterli olma düzeyi ki-kare testi ve binary lojistik regresyon ile analiz edilmiştir.
Bulgular: Araştırmaya katılanların %47,3’ü kadın, %67,5’i evli, %48,3’ü 65-69 yaş grubunda, %80,5’nin en az 1 kronik hastalığı bulunmakta ve %65,5’i yardımcı araç kullanmaktadır. Fiziksel ve ruhsal sağlık puan ortalaması sırasıyla 37,94 ve 41,85’dir. Yaşlıların %67,0’si hastane içi ve %23,8’i hastane çevresi düzenlemelerin güvenlik ve konforu için olumlu görüş bildirmiştir. Hastane içi düzenlemeleri yeterli düzeyde güvenli ve konforlu bulma olasılığı, şehir hastanesine başvuranlar, erkekler, evliler, il merkezinde yaşayanlar, fiziksel sağlık puanı yüksek olanlar arasında daha yüksek saptanmıştır.
Sonuç:	Yaşlıların 2/3’ü hastane içi düzenlemelerin güvenlik ve konforunu yeterli olarak değerlendirmiştir. Yaşlıların fiziksel yaşam kalitesi yükseldikçe hastaneyi fiziksel olarak daha yeterli değerlendirirken, ruhsal yaşam kalitesi ile bir ilişki bulunmamıştır.
Öncü Sûfîlerden Fudayl b.‘Iyâd’ın (öl.187/802) İlmî Şahsiyeti
Authors: AKDAĞ Eyyup 
Published: May 2020

Tâbi‘înden sonraki ilk tabakada yer alan öncü sûfîlerden Fudayl b.
‘Iyâd, İslam ilim tarihinin önemli isimlerinden birisidir. Neseben Arap olan Fudayl’ın hayatı Horasan,
Kûfe ve Mekke olmak üzere üç bölgede geçmiştir. Kûfe yıllarını yoğun bir
şekilde ilim tahsili ile geçiren Fudayl’ın üstadları arasında Ebû Hanîfe, Mansûr
b. el-Mu‘temir, ‘Atâ b. es-Sâib, Ebû Muhammed el-A‘meş ve Süfyân es-Sevrî gibi
bazı isimler yer almaktadır. İslâm ilim tarihinin etkili şahsiyetler eliyle
yetişen Fudayl’ın talebeleri arasında Süfyân b. ‘Uyeyne, Abdullah b. Mübârek ve
İmâm Şâfi‘î gibi bazı önemli isimleri de zikretmek gerekir. Zamanın önde gelen
âlimlerinden kabul edilen Fudayl, tasavvufî neşvesiyle de temeyyüz etmektedir.
Bu çalışmada Fudayl’ın tasavvufî yönü değil daha ziyade ilmî yönü ele
alınacaktır. İlim ve amel bütünlüğünü savunan Fudayl amele sevketmeyen ilmi faydasız
ve fuzuli gördüğü gibi ameli de imanın bir parçası görmüş, amelsiz imanı kabul
etmemiştir. Manevî hayatını hep ilmin rehberliğinde tanzim etmiştir. Kur’ân ve
sünnet bütünlüğüne dikkat çeken Fudayl, dinî hayatın ikâmesinde Kur’ân ve
sünnetten sadece biriyle yetinilmesini doğru bulmamıştır. Görüş ve
düşünceleriyle Ehl-i sünnetin teşekkülüne ve bu anlayışın toplumda hâkim
olmasına katkı sağlayan Fudayl, Ehl-i sünnet dışı gördüğü bid‘at ehli fırkalara
karşı da yoğun bir fikrî mücâdele içinde yer almıştır. Onun anlayışına göre
dinin ikâmesi ancak ehl-i bid‘atle mücâdeleyle mümkün olmaktadır.
Síndrome de apnea obstructiva del sueño y origen fetal arteria cerebral posterior: primer reporte de caso
Authors: Amado-Galeano Steve , Posada-Alvarez Mary Eugenia , Parra-Correa Laura 
Published: May 2020

Los pacientes que presentan síndrome de Apnea-Hipopnea Obstructiva del sueño asociado a malformaciones cerebrovasculares tienen un riesgo aumentado de complicaciones vasculares isquémicas al no recibir el manejo médico adecuado y afectar asi su calidad de vida. La incidencia de malformaciones cerebrovasculares en este tipo de pacientes es desconocida, por lo que es necesario realizar estudios imagenológicos y polisomnográficos en pacientes que cursan con eventos cerebrovasculares.
Se presenta caso clínico de un paciente masculino de 57 años de edad, con antecedente de dos eventos cerebrovasculares asociado a cefalea de difícil control, somnolencia diurna, roncopatia crónica y apnea del sueño, a quien se le realizaron estudios de extensión, se diagnosticó Síndrome de Apnea-Hipopnea Obstructiva del sueño severa asociado a Origen fetal de arteria cerebral posterior; recibió manejo con equipo de presión positiva con el cual ha tenido control de síntomas y mejoría de su calidad de vida.
Resultados postoperatorios de cierre quirúrgico de perforación septal con injertos de cartílago.
Authors: Taborda María Alejandra , Orozco Manuela , Zamora Cely Lina Margarita 
Published: May 2020

Introduccio?n: Las perforaciones septales y su correccio?n quiru?rgica constituyen un reto para los otorrinolaringo?logos. Se encuentran descritas en la literatura diferentes te?cnicas para el cierre de perforaciones septales; sin embargo, sus resultados en te?rminos de efectividad son muy variables y con pocos pacientes. Desde hace 8 an?os se viene realizando la te?cnica de cierre de perforacio?n septal con injertos de carti?lago en el servicio de otorrinolaringologi?a del Hospital San Jose? y se ha observado una respuesta cli?nica exitosa.
Objetivo: describir los resultados postoperatorios de los pacientes manejados con la te?cnica de cierre quiru?rgico de perforacio?n septal con injertos de carti?lago, en te?rminos de aparicio?n de complicaciones y frecuencia de perforacio?n septal residual. Disen?o: estudio de tipo cohorte descriptiva.
Metodologi?a: se describe una cohorte de pacientes manejados con la te?cnica de cierre quiru?rgico de perforacio?n septal con injertos de carti?lago de banco o carti?lago auto?logo. Se incluyeron pacientes a partir de enero de 2014 a junio de 2018. Se extrajeron de la historia cli?nica los datos demogra? cos, cli?nicos, complicaciones y presentacio?n de perforacio?n septal residual.
Resultados: la tasa de e?xito de cierre de perforacio?n septal fue de 78,3 %; siendo las etiologi?as ma?s frecuentes antecedente de cirugi?a e idiopa?tica. La complicacio?n ma?s comu?n fue epistaxis en el 26 % de los pacientes, seguida de dolor en el 21,7 % en el postoperatorio mediato, el cual mejoro? en los controles posteriores. Conclusio?n: Los resultados con la te?cnica de cierre de perforacio?n septal con injerto de banco fueron satisfactorios en esta poblacio?n.