bluuebunny/crossref_metadata_2025_split huggingface dataset:
Actividad neuroprotectora de Solanum ovalifolium (Solanaceae) contra la toxicidad inducida por rotenona en Drosophila melanogaster
Authors: Jiménez Erika V. , Tovar Jennifer , Mosquera Oscar M. , Cardozo Fernando 
Published: April 2020

Los objetivos de este trabajo fueron evidenciar la presencia de flavonoides en el extracto metanólico de Solanum ovalifolium por cromatografía líquida de alta eficiencia (HPLC-UV), analizar la actividad antioxidante por los métodos de 1,1-difenil-2-picrilhidrazilo (DPPH•) y ácido 2,2'-azinobis-(3-etilbenzotiazolina)-6-sulfónico (ABTS•+), cuantificar el glutatión (GSH), las unidades de enzima antioxidante superóxido dismutasa (SOD) y determinar el efecto neuroprotector contra la toxicidad inducida por rotenona (100 µM) con el modelo in vivo de Drosophila melanogaster mediante geotaxis negativa y cuantificación de la dopamina (DA) de las células cerebrales por (HPLC-UV). A través del perfil fitoquímico por cromatografía líquida de alta eficiencia (HPLC-UV) se evidenció un alto contenido de flavonoides, principalmente dihidroxiflavona (83.33%) y flavona-flavonol (16.66%), el extracto presentó una concentración media inhibitoria para los radicales DPPH• y ABTS•+de 179.8 µg/mL y 34.4 µg/mL respectivamente. En el extracto de S. ovalifolium a 1000 mg/L se cuantificó 4.28 nmol de GSH/ mL de extracto y 1.43 unidades SOD/mL del extracto. En la evaluación del efecto neuroprotector, las moscas macho variedad silvestre (75) co-expuestas a 7 días de tratamiento con el extracto metanólico de S. ovalifolium 0.1% presentaron un menor efecto tóxico y una protección completa contra el estrés oxidativo inducido por rotenona. El contenido de dopamina fue de 61-65 µg/L. Adicionalmente, este trabajo confirma la utilidad del modelo in vivo de D. melanogaster como una etapa en la evaluación de posibles medicamentos neuroprotectores.
CONCEPTUAL MODEL OF POLITICS IN AMERICAN ENGLISH
Authors: Tatsenko Nataliia , Stepanov Vitalii , Shcherbak Hanna 
Published: April 2020

Purpose of the study: The research is aimed at reconstructing a conceptual model of POLITICS as a social phenomenon that is activated by the word politics in the minds of American people.
Methodology: As an appropriate methodology, “the semantics of lingual networks” (SLN)is used to analyze a 1000-context sample of the word politics from the Corpus of Contemporary American English (COCA). Specifically, a range of logical predicates (associated with POLITICS) is established and sorted by propositional schemas of basic frames. The latter is reproduced graphically in the network conceptual form and equated to the denotative meaning of POLITICS.
Main findings: The conducted research made it possible to define 26 propositional schemas that are regarded as the conceptual model of POLITICS in American English.
Novelty/originality: The research is the first attempt to study social phenomena via linguistic tools only – those of cognitive linguistics (the SLN methodology) and corpus linguistics (analysis of a COCA sample where these phenomena are represented) – rather than via techniques of politology, sociology, psychology and other social sciences themselves. Along with the conceptual model of POLITICS, the first-ever idea to convert it into the field cognitive model is offered as well (via operations of cognitive interpretation and prominence). As a result, the final model can be used to define what features of POLITICS are mentally the most relevant for the American community. The possibility of comparing several cognitive models of POLITICS is also stated.
Applications of the study: The research results can be used for politological, sociological and psychological studies; to compile new curricula for philology undergraduates and postgraduates.
FINANCIAL MANAGEMENT MODEL FOR FORMAL WORKERS IN INDONESIA
Authors: Indrawati Novy Karmelita , Widjaja Sri Umi Mintarti , Wahjoedi  , Haryono Agung 
Published: April 2020

Purpose of the study: This paper is intended to understand the investment pattern for formal workers in Indonesia. Thus, it is also aimed to provide a specific form of variable construction of productive financial management for workers.
Methodology: This study followed qualitative research by emphasizing the active interaction of the subject and the object of researchers in the form of a discussion to determine the ideas or basic reference model of productive financial management, specifically and focus on each individual form in which the organization is located. The data were gathered using in-depth interviews with respondents in the category of civil servants, state-owned and private employees with lower, middle, and upper-level segregation of interests and reasons for making investment decisions.
Main Findings: The findings showed that the investment decision making for formal sector workers are motivated by benefits and financial security in the future. Their investment decision also considers the income received by individuals in each type of institution. Lastly, technology contributes to change investors’ economic behaviour. The ease of getting information strengthens the motivation of formal sector workers in productive financial management.
Applications of this study: This study provides an investment decision model for formal workers that can be considered ways to enhance the individual understanding of investment.
Novelty/Originality of this study: This study aims to contribute to this growing area of research by exploring investment patterns for formal workers then propose a financial management model for workers.
RELIGIOUS CULTURE DEVELOPMENT IN COMMUNITY SCHOOL: A CASE STUDY OF BOYOLALI MIDDLE SCHOOL, CENTRAL JAVA, INDONESIA
Authors: Fatimah Meti , Sutama  , Aly Abdullah 
Published: April 2020

Purpose: This study aims to explore the religious culture development in the community school for public junior high schools in Boyolali, Indonesia.
Methodology: This research employs a qualitative approach with interviews and observation as its main research tools for data collection. Three schools participated in this study. Namely: SMP Negeri 4 Boyolali, SMP Negeri 2 Boyolali, and SMP Negeri 6 Boyolali.
Findings: This research reveals three main themes for developing a religious culture in the school community; firstly creating a systematic model of school policy; secondly, building cooperation with school leaders and citizens; and lastly, developing a religious culture through extracurricular activities.
Implications of the study: The results of this study may be useful for the government in Indonesia as a reference in the development of religious culture in schools or may be useful for the development of religious cultural education in an area.
Novelty: Student backgrounds greatly influence religious behavior, as well as school policies, which will also influence the development of religious culture, so the development of religious culture will affect the growth of student character.
This study creates a systematic school policy model, builds cooperation between school leaders and citizens, and develops a religious culture through extracurricular activities in the school community, to be further enhanced by good management and clear regulations. The 2003 National Education System Law states that the first and foremost criteria in the formulation of these goals are people who believe in and fear of God Almighty and have good character. For religious culture to be applied in educational institutions, the importance of religion, cultural education needs to be developed.
THE CONDUCT OF RISK MANAGEMENT IN TRADE FINANCING PROCESSES: EXPLORING THE PROSPECTS AND CHALLENGES IN FINTECH ERA
Authors: Mohd Sapian Safeza , Ibrahim Norhazlina , Hj. Shahwan Syahidawati 
Published: April 2020

Purpose of the study: To investigate the conduct of risk management in trade financing processes as well as to identify potential issues in risk management relating to fintech in trade financing. At the same time, this study had the opportunity to explore all possible prospects and challenges that this new era of digital could offer to the banking industry.
Methodology: The study employed an interview with experts for the means of data collection with the aim of gathering a wide range of information and opinion from the industry experts on the subjects of this study. The data collected from interview transcripts are analysed contextually based on thematic analysis and framework analysis.
Main Findings: The findings suggested risk management in trade financing processes is critical due to the nature of cross-country transactions and the current era of fintech has further escalated the risk exposure to fintech-related types of risk. Strategies to improve the current conduct of risk management in trade finance processes have been identified where opportunities and challenges can be managed effectively.
Applications of this study: Findings from this study will give valuable insights to the banking and finance industry’s practitioners, especially those who are directly involved in trade financing processes as well as the top management of the banks to further improve current risk management practices in particular catering for the new fintech era. This is essential in facing the wave of the 4th industrial revolution.
Novelty/Originality of this study: This study has contributed to the limited number of published studies in this area. Most importantly, the attempt to investigate the current practice of risk management and identify actual issues and problems in trade financing processes through financial technology platform has not been researched and explored before.
Prevalencia de lesión escamosa intraepitelial en pacientes con atipias de células glandulares. Hallazgos colposcópicos e histopatológicos en una institución de referencia en Bogotá, Colombia
Authors: Corredor-Sánchez Eugenia , Castillo Marcos 
Published: April 2020

Objetivos: determinar la prevalencia de la lesión escamosa intraepitelial y la validez diagnóstica del curetaje endocervical en pacientes con citología informada con atipias en células glandulares.Metodología: se llevó a cabo un estudio de corte transversal en pacientes con atipias en células glandulares en la citología, del Hospital Universitario de La Samaritana, de tercer nivel de atención en Bogotá, Colombia, durante el periodo de enero del 2000 a junio del 2006.Criterios de inclusión: información completa de citología con atipias glandulares, colposcopia y curetaje endocervical. Los datos se procesaron en el programa estadístico SPSS, V.15.Resultados: se analizaron 105 mujeres con resultados positivos de citología para atipias glandulares. La prevalencia de lesión cervical intraepitelial fue del 53% en mujeres con AGC, de estas correspondió a LEI de bajo grado el 46,5% y LEI de alto grado el 7%. El curetaje endocervical fue informado en el 86,7% como negativo para la lesión, el 13,3% reportaron lesión intraepitelial de bajo grado y en 22 como muestra insuficiente. La lectura del epitelio exocervical fue negativa en 46,5% e igual proporción para lesión intraepitelial de bajo grado y de alto grado en el 7%. La concordancia entre la biopsia exocervical y el curetaje endocervical mostró un Kappa de 0,07.Conclusión: hay una alta prevalencia de lesión cervical intraepitelial, fue del 53% en mujeres con AGC. Ninguna de las mujeres tuvo resultado positivo para carcinoma escamocelular o adenocarcinoma.
Traquelectomía laparoscópica después de histerectomía subtotal: reporte de dos casos en Medellín, Colombia
Authors: De Los Ríos José F. , Ochoa Juan C. , Castañeda Juan D. 
Published: April 2020

Objetivo: reportar dos casos de traquelectomía por laparoscopia.Institución: Unidad de Cirugía Endoscópica Ginecológica, Clínica del Prado, Medellín, Colombia.Diseño: se presenta el reporte de dos pacientes con muñón cervical sintomático después de histerectomía subtotal y su manejo por vía laparoscópica.Variables: se describen los datos demográficos de las pacientes, el diagnóstico prequirúrgico, la técnica empleada para la remoción del cérvix y los datos de la evolución posoperatoria.Conclusiones: la evidencia disponible cataloga el abordaje laparoscópico como seguro para la realización de traquelectomía en casos de enfermedad benigna. Este es el primer reporte de traquelectomía laparoscópica publicado en la literatura colombiana.
Doppler de arteria umbilical con flujo reverso intermitente en embarazo gemelar monocorial biamniótico con RCIU selectivo: reporte de un caso y revisión de la literatura
Authors: Gálvez María L. , Rodríguez Nadiezdha , Gómez Iván , Puccini Giuliana , Sarmiento Andrés , Quijano Fabio 
Published: April 2020

Objetivo: revisar la literatura existente acerca del retardo de crecimiento intrauterino discordante en el embarazo gemelar, en cuanto a las características de doppler de la arteria umbilical, la fisiopatología del patrón que representan sus ondas y las implicaciones como factor pronóstico de bienestar fetal y manejo.Se presenta un caso clínico de paciente con estudio de doppler reverso intermitente de arteria umbilical en feto con restricción de crecimiento intrauterino (RCIU) discordante de gestación gemelar monocorial biamniótico.Discusión: la literatura revisada mostró que el embarazo gemelar monocorial tiene formas únicas de relaciones vasculares entre sus fetos, que hacen que se dibujen ondas doppler específicas para la arteria umbilical que tienen al parecer una correlación clínica directa con el desenlace de estos embarazos; sin embargo, falta evidencia suficiente que soporte estos hallazgos para poder, de manera concreta, definir patrones de doppler de la arteria umbilical y dar un pronóstico certero de cada uno.
Antagonistas de receptores de progesterona (PRA) y moduladores selectivos de receptores de progesterona (SPRM): aplicaciones en ginecología y obstetricia
Authors: Suárez-Calderón Diana Marcela , Díaz-Yamal Ivonne 
Published: April 2020

Dos décadas de estudio bioquímico, farmacológico y clínico han permitido la síntesis de antagonistas del receptor de la progesterona (PRA) y moduladores selectivos de receptores de progesterona (SPRM).El receptor de progesterona (PR) comparte la estructura de los receptores esteroideos que al ser estimulados sufren un cambio conformacional y subsecuentemente activan la transcripción genética en un tejido específico. Dicho proceso depende, particularmente en el PR, del equilibrio existente entre coactivadores y correpresores que ya han sido identificados. El mifepristone ha sido catalogado como PRA, mientras que el asoprisnil es el clásico SPRM agonista-antagonista. Múltiples estudios experimentales y clínicos han evidenciado la utilidad de los PRA y los SPRM en escenarios clínicos tan comunes como la miomatosis uterina, la endometriosis, la terminación del embarazo y la anticoncepción. Sin embargo, aún no existe la molécula ideal y faltan estudios que respalden la seguridad y eficacia de mifepristone y asoprisnil a largo plazo. El objetivo del presente documento es revisar la farmacodinamia y usos clínicos de estos medicamentos en ginecología y obstetricia.
Analysis of Final-year Students Self-Awareness Using Reference Management Software
Authors: Avidiansyah Zulfa , Kurniajaya James Frederich 
Published: April 2020

Background of the study: Academic environments such as universities have never been separated from the activities of scientific writing. In scientific writing, there is information that needs to be studied through various literature as a basis for writing. Literature as reference material in scientific papers needs to be managed so that it can be included in the bibliographic list according to the applicable rules. Management of bibliographic lists with various writing styles can be helped by using software assistance. Observations made by the authors at the Universitas Gadjah Mada (UGM) Graduate School Library, many of theses from students are still not appropriate in the procedure for writing the bibliography. So, it becomes a question of how the final level self-awareness of students in the use of citation/reference software. Purpose: Therefore, in this pilot study, the aim was to see and provide an initial description of the final-year students of self-awareness in the use of citations/reference management software. Method: Quantitative methods were used in this study and surveys were conducted to obtain data by adopting and modifying the Self-Awareness Outcomes Questionnaire (SAOQ) to measure student self-awareness. Findings: The results of the survey that have been carried out, the final level students of the Master of Culture and Media Study Program, the Graduate School of UGM have self-awareness in the use of citation/reference software. Conclusion: This researchcan be used as an initial step in further research and a reflection for libraries to always assist students.
Native Mycorrhizal Fungi in Land Contaminated Cr, Co and Cu
Authors: Akib Muhammad Akhsan , Nuddin Andi , Prayudyaningsih Retno , Syatrawati Syatrawati , Setiawaty Henny 
Published: April 2020

Mycorrhizal fungi that are capable of adapting and resistant to heavy metal contaminated environments have received special attention for phytorhizoremediation researchers. The aim of the study was to explore native mycorrhizal fungi from areas contaminated with heavy metals to be used as starter biological agents in the phytorhizoremediation program. This research was carried out in two phases, i.e. rhizosphere sampling of Polypodium glycyrrhiza, Sumasang sp (local name) and Spathoglottis plicata at coordinates 2O31'57,6"S and 121O22'50,7"E. Rhizosphere of Chromolaena odorata, Melastama affine and Nephrolepis exaltata at coordinates 2O31'53,5"S and 121O22'35,4"E, Sorowako, Indonesia; While the other phase is isolating and identifying mycorrhizal spores in the Microbiology Laboratory, Research and Development Center for Environment and Forestry in Makassar, Indonesia. The results showed that be discovered three genus of mycorrhizal fungi were able to adapt and resistant in areas contaminated with Cr, Co, and Cu, i.e. 44.44% to 75.86% Acaulospora sp; 9.52% to 44.44% Gigaspora sp, and 3.38% to 19.05% Glomus sp. which could be used as source of inoculum in Phyto-rhizoremediation program. We recommend using native mycorrhizal fungi combined with endemic plant of location to rehabilitation heavy metal contaminated soils.
Phytoremediation effect of Medicago sativa colonized by Piriformospora indica in the phenanthrene and cadmium co-contaminated soil
Authors: Li Liang , Zhu Pengyue , Wang Xiaoyang , Zhang Zhenhua 
Published: April 2020

Abstract
Background: The coexistence of polycyclic aromatic hydrocarbons (PAHs) and heavy metals has deleterious effects on environmental quality. Few reports have studied the mechanisms of plant inoculation with Piriformospora indica to remediate PAH-metal co-contaminated soil by analyzing the chemical speciation of the contaminants. This study investigated the influence of the inoculation of Medicago sativa with P. indica to remediate soil co-contaminated with phenanthrene (a kind of PAH) and cadmium (a heavy metal) by analyzing plant growth, physiological parameters and chemical speciation in rhizosphere and nonrhizosphere soils.Results: The presence of P. indica significantly increased plant tolerance, chlorophyll a, chlorophyll b, maximum quantum efficiency of PSII photochemistry and electron transport rate values in phenanthrene- and/or cadmium-contaminated soil. P. indica inoculation in M. sativa roots increased fluorescein diacetate activities in soils contaminated with phenanthrene, cadmium or both, especially in the nonrhizosphere. The presence of phenanthrene prevented the inoculated plant from accumulating cadmium to some extent, whereas the presence of cadmium did not prevent the degradation of phenanthrene in either the rhizosphere or the nonrhizosphere after P. indica colonization. Although the low bioavailability of cadmium in the rhizosphere restricted its transportation into the stem, P. indica colonization in plants effectively increased cadmium accumulation in roots in soil co-contaminated with cadmium and phenanthrene.Conclusions: In conclusion, this work provides a theoretical basis for the use of P. indica combined with M. sativa for the remediation of PAH-metal co-contaminated soil.
Depression, anxiety, and burnout among medical students and residents of a medical school in Nepal: a cross-sectional study
Authors: Pokhrel Nishan Babu , Khadayat Ramesh , Tulachan Pratikchya 
Published: April 2020

Abstract
Background: Medical students and residents were found to have suffered from depression, anxiety, and burnout in various studies. However, these entities have not been adequately explored in the context of Nepal. We proposed to determine the prevalence of depression, anxiety, burnout, their associated factors, and identify their predictors in a sample of medical students and residents in a Nepalese medical school.Methods: It was a cross-sectional study with 651 medical students and residents chosen at random between December 2018 and February 2019. The validated Nepali version of Hospital Anxiety and Depression Scale, the Copenhagen Burnout Inventory, and Medical Students' Stressor Questionnaire were used to assess depression, anxiety, burnout, and stressors respectively. We used univariate and multivariable logistic regression analyses to identify the correlation of predictor variables with depression, anxiety, and burnout.Results: The overall prevalence of burnout (48.8%; 95% CI 44.9-52.7) and anxiety (45.3%; 95% CI 41.4-49.2) was more than that of depression (31%; 95% CI 27.5-34.7). Burnout and depression were more prevalent in residents than in medical students (burnout: 64.5% vs 37.6%, P-value < 0.0001; depression: 33.7% vs 29.1%, P-value 0.21). Whereas, medical students were found more anxious than residents (46.3% versus 43.96%, P-value 0.55). Academic related stressors caused high-grade stress to participants. Multivariable model for depression significantly showed anxiety, personal burnout, and work-related burnout as risk enhancing correlates; satisfaction with academic performance as a protective correlate. Similarly, the multivariate model for anxiety significantly identified female gender, depression, personal burnout, teaching and learning related stressors, and past history of mental illness as risk enhancing correlates; being satisfied with academic performance, getting adequate sleep, and being a second-year resident as protective correlates. The logistic model for burnout significantly showed being a first-year resident, depression, anxiety, and drive and desire related stressors as positive predictors. None of the variables were identified as significant negative predictors of burnout. Conclusions: A high prevalence of depression, anxiety, and burnout was seen among medical students and residents. Most of them were stressed with academic-related factors. A strong correlation between teaching and learning-related stressors with depression and anxiety may be a call for an efficient and more student-friendly curriculum.