bluuebunny/crossref_metadata_2025_split huggingface dataset:
Completion of the gut microbial epi-bile acid pathway
Authors: Doden Heidi L. , Wolf Patricia G. , Rex Gaskins H. , Anantharaman Karthik , Alves João M. P. , Ridlon Jason M. 
Published: September 2020

ABSTRACTBile acids are detergent molecules that solubilize dietary lipids and lipid-soluble vitamins. Humans synthesize bile acids with α-orientation hydroxyl groups which can be biotransformed by gut microbiota to toxic, hydrophobic bile acids, such as deoxycholic acid (DCA). Gut microbiota can also convert hydroxyl groups from the α-orientation through an oxo-intermediate to the β-orientation, resulting in more hydrophilic, less toxic bile acids. This interconversion is catalyzed by regio-(C-3 vs. C-7) and stereospecific (α vs. β) hydroxysteroid dehydrogenases (HSDHs). So far, genes encoding the urso-(7α-HSDH & 7β-HSDH) and iso-(3α-HSDH & 3β-HSDH) bile acid pathways have been described. Recently, multiple human gut clostridia were reported to encode 12α-HSDH, which interconverts DCA and 12-oxolithocholic acid (12-oxoLCA). 12β-HSDH completes the epi-bile acid pathway by converting 12-oxoLCA to the 12β-bile acid denoted epiDCA; however, gene(s) encoding this enzyme have yet to be identified. We confirmed 12β-HSDH activity in cultures of Clostridium paraputrificum ATCC 25780. From six candidate C. paraputrificum ATCC 25780 oxidoreductase genes, we discovered the first gene (DR024_RS09610) encoding bile acid 12β-HSDH. Phylogenetic analysis revealed unforeseen diversity for 12β-HSDH, leading to validation of two additional bile acid 12β-HSDHs through a synthetic biology approach. By comparison to a previous phylogenetic analysis of 12α-HSDH, we identified the first potential C-12 epimerizing strains: Collinsella tanakaei YIT 12063 and Collinsella stercoris DSM 13279. A Hidden Markov Model search against human gut metagenomes located putative 12β-HSDH genes in about 30% of subjects within the cohorts analyzed, indicating this gene is relevant in the human gut microbiome.
Technological transformation, culinary tourism and stakeholder engagement: emerging trends from a systematic literature review
Authors: Schimperna Federico , Lombardi Rosa , Belyaeva Zhanna 
Published: September 2020

Purpose
This paper aims to pinpoint the technological transformation impact on food as the cultural phenomenon for destination brand identity and management as the novel approach for the stakeholder causal scope (SCS) analysis in culinary tourism. Thus, this paper attempts to answer the following research question: What is the role of technological transformation in addressing stakeholder engagement of culinary tourism?

Design/methodology/approach
The research is based on the systematic two-decade literature review of technological transformation for SCS analysis in culinary tourism. This paper adopted a longitudinal study of ABS2018 list – 2-, 3-, 4- and 4*-star journal articles, collecting literature within the field “sector” and Scopus databases as relevant source to collect articles.

Findings
Following the current severe acute respiratory syndrome Coronavirus 2 emergency to move certain industries to digital space, including culinary tourism, the main findings are directed to advance technological transformation knowledge in culinary tourism to extend the existing framework on SCS.

Originality/value
The novelty of this research is confirmed with the contemporary call for technological transformation in culinary tourism assuming that SCS analysis allows examining the status quo and explores future research agenda and practical implications in post-Covid era.
Surviving the Arab Spring: socially beneficial product portfolios and resilience to political shock
Authors: Darendeli Izzet , Hill T.L. , Rajwani Tazeeb , Cheng Yunlin 
Published: September 2020

Purpose
This paper aims to explore the ideas that social legitimacy (acceptance by the public within a country) serves as a hedge against political risk and that the perceived social value of Multinational Enterprises (MNEs’) products or services improves firms’ social legitimacy and so resilience to political shock.

Design/methodology/approach
Drawing from a unique data concerning global construction activity and taking advantage of the Arab Spring as an exogenous, political shock, this paper teases out the relative effects of pre-shock experience and product/service emphasis.

Findings
The authors find that construction firms that worked on a higher proportion of socially beneficial projects – such as water infrastructure, transportation and telecommunications – recovered more quickly from political shock than did those that worked on projects primarily for manufacturing interests or the oil industry. The authors also find that deep experience in a country had no bearing on a firm’s ability to recover from political shock.

Originality/value
The findings suggest that market behaviors that enhance social legitimacy also enhance MNEs’ ability to survive in volatile political settings. These insights add to the political risk and nonmarket strategy literatures the idea that market strategies that are attentive to nonmarket strategic goals are an important addition to the toolkit for managing political risk. More specifically, when it comes to surviving political shock, pre-shock emphasis on socially beneficial products seems to create a social legitimacy buffer that enhances resilience more than do deep country experience and associated social and political ties with the political elite.
Online mental health communities, self-efficacy and transition to further support
Authors: Prescott Julie , Rathbone Amy Leigh , Hanley Terry 
Published: September 2020

PurposeThis study is exploratory research which aims to understand how users gain support from the online mental health community (OMHC) 18 percent and whether engagement with this community may possibly lead to increased self-efficacy.Design/methodology/approachIn total, 128 users of an OMHC, 18 percent, completed an online questionnaire that asked open-ended questions about the community and how users engaged with it. The results were analysed using quantitative and qualitative methods.FindingsBased on the construct of self-efficacy within social cognitive theory, it is evident that the platform provides users with increased self-efficacy and encourages further support seeking in a professional capacity, either via an online or offline platform.Originality/valueOMHCs provide a therapeutic, peer-to-peer space for users in times of crisis which have the possibility to increase self-efficacy when engaged with. However, users must acknowledge that although the online platform is an efficacious resource, it cannot be used as a principal proxy for offline treatment.
The effect of installed photovoltaic panels on the aesthetic perception and evaluation of the mosque architectural form in Jordan
Authors: Ibrahim Anwar , Ali Hikmat H. , Alqarra Wala'a 
Published: September 2020

Purpose
This study aims to evaluate the effect of the installed photovoltaic (PV) systems on the aesthetic perception of the mosque’s architectural form. It also aims to develop a framework for integrating PV cells with the various elements of the building type.

Design/methodology/approach
The study adopted a mixed-method approach comprising both qualitative and quantitative techniques for data collection procedures. This includes surveys, literature review, focus groups and an experiment.

Findings
The results revealed a negative impact of the building-applied PV panels on people’s perception of the mosque’s architectural form. However, integrating the PV cells with the mosque form was perceived as more aesthetically pleasing. Certain integrating PV strategies integrated more harmoniously with certain mosque styles.

Research limitations/implications
This study is focused on limited styles of one building type. Extra research is needed to explore the differences between the different participated groups.

Originality/value
There is a lack of research that explores the ways the installed PV systems impact the users’ architectural aesthetic perception of the mosque. This study informs the design process and practice and construction industry by highlighting the opportunities PV systems, as a legitimate sustainable energy resource, offers to architects and manufacturers.
Technology innovation in the Nigerian banking system: prospects and challenges
Authors: Ohiani Adeku Salihu 
Published: September 2020

PurposeThe banking system in Nigeria is gradually moving away from transactions “across the counter” to the fingertips of the customers with the adoption of modern technology. However, every development comes with its “pros and cons” because as technology innovation has improved service delivery and profitability of banks in Nigeria, crimes are also at a high side. To activating the minds of bank operators about the importance of technology adoption and its shortcomings, this paper aims to examine the prospects and challenges of technology innovation in the Nigerian banking system.Design/methodology/approachSecondary data were retrieved from the annual reports of Central Bank of Nigeria (CBN) and Nigeria Deposit Insurance Corporation (NDIC) from 2013 to 2017 to know the interaction between e-banking platforms and performance of banks in Nigeria. The study administered a questionnaire to the bank customers in Lagos Island, Nigeria to understand their perception towards e-banking. This study is anchored on prospect theory to ascertain the risk orientation of the Nigerian banks regarding how they adopt technology and reasoned action theory to understand the intention of bank customers in using the opportunities of e-banking copiously.FindingsThe findings of this study reveal the migration from cheques to electronic related transactions. It further indicates a high rate of fraud committed through those channels. The analysis of primary data shows that innovation adoption, service quality, cybercrime have significant relationship with the competitiveness of banks, the intention of bank customers, and perception of customers towards online services. However, the rate of frauds does not have significant relationship with the usage of mobile banking products which further studies can critically examine.Originality/valueThis study has revealed available huge potentials in the e-banking that are yet to be used in Nigeria. However, consumer orientation needs to be worked on, because, customers still have the fear that cybercrime is mostly committed via e-banking platforms. Unlike in developed countries whereby quite good numbers of customers make use of e-banking platforms, majority of bank customers in Nigeria still prefer using manual methods and the world is already on the verge of moving into 5 G from 4 G.
Hepatitis C virus genotypes in patients with chronic hepatitis C infection in southern Iran from 2016 to 2019
Authors: Namayandeh Mandana , Jamalidoust Marzieh , Heydari Marandi Nahid , Aliabadi Nasrin , Ziyaeyan Atoosa , Pouladfar Gholamreza , Ziyaeyan Mazyar 
Published: September 2020

AbstractHepatitis C is a liver disease caused by the hepatitis C virus (HCV). The treatment of HCV infection has become more complicated due to various genotypes and subtypes of HCV. The treatment of HCV has made significant advances with direct‐acting antivirals. However, for the choice of medicine or the combination of drugs for hepatitis C, it is imperative to detect and discriminate the crucial HCV genotypes. The main objective of this study was to determine the pattern of circulating HCV genotypes in southern Iran, from 2016 until 2019. The other aim of the study was to determine possible associations of patients’ risk factors with HCV genotypes. A total of 803 serum samples were collected in 4 years (2016–2019) from patients with HCV antibody positive results. A total of 728 serum samples were HCV‐RNA positive. The prevalence of HCV genotypes was detected using the genotype‐specific RT‐PCR test for serum samples obtained from 615 patients. The HCV genotype 1 (G1) was the most prevalent (48.8%) genotype in the area, with G1a, G1b, and mixed G1a/b representing 38.4%, 10.1%, and 0.3%, respectively. Genotype 3a was the next most prevalent (47.2%). Mixed genotypes 1a/3a were detected in 22 (3.6%) and finally G4 was found in 3 (0.5%) patients. The other HCV genotypes were not detected in any patient. Genotype 1 (1a and 1b alone, 1a/1b and 1a/3a coinfections) is the most prevalent HCV genotype in southern Iran. HCV G1 shows a significantly higher rate in people under 40 years old.
Assessing the effects of oil palm replanting on arthropod biodiversity
Authors: Pashkevich Michael D. , Aryawan Anak Agung Ketut , Luke Sarah H. , Dupérré Nadine , Waters Helen S. , Caliman Jean‐Pierre , Naim Mohammad , Turner Edgar C. 
Published: September 2020

Abstract

Palm oil is the most traded vegetable oil worldwide. Production is concentrated in Southeast Asia, where established oil palm plantations dominate the landscape in many regions. Although levels of biodiversity are much lower than in forest, mature oil palm plantations can support a wide range of generalist species. However, these species may be threatened, as large areas of plantation have already been, or will soon be, replanted as they near the end of their productive life (20–30 years). Replanting changes vegetation complexity and microclimate, but short‐ and long‐term effects on biodiversity are largely unstudied.

We surveyed an oil palm chronosequence (first‐generation mature palms, and replanted second‐generation palms aged 1, 3 and 8 years) in an industrial plantation in Riau, Indonesia to assess the impacts of replanting over an 8‐year period on arthropods in the ground, understorey and canopy microhabitats. Replanting was carried out using current recommended strategies, which included staggering replanting events to promote landscape‐level heterogeneity, retaining mature oil palm riparian buffers, planting a cover crop immediately after replanting, and using chopped mature palms as mulch after clearance. We assessed changes in total arthropod abundance and order‐level community composition, as well as specific changes in spider communities.

We observed no significant declines in total arthropod abundance after replanting, but arthropod order‐level community composition varied across the chronosequence in all microhabitats. These findings were replicated, or more pronounced, in spider‐specific analyses. Spider abundance and species richness decreased in the understorey in the first year after replanting (although these returned to pre‐replanting levels after 3 years), and spider species‐level community composition in all microhabitats differed significantly across the chronosequence.

Synthesis and applications. Our findings indicate that total arthropod abundance is resilient to replanting of oil palm, but that replanting changes total arthropod and spider community composition and decreases spider abundance and species richness in some microhabitats. While it is somewhat encouraging from a management perspective that recommended replanting strategies maintain overall arthropod abundance, the changes in arthropod composition and spider biodiversity that we observed may impact ecosystem processes, such as pest control, in second‐generation oil palm plantations, with potential implications for yield. Additional studies that focus on other taxonomic groups and assess the effects of individual replanting strategies are needed before the long‐term ecological impacts of replanting on existing oil palm plantations can be fully determined.
Macroeconomic Policy to Aid Recovery after Social Distancing for COVID‐19
Authors: McDonald Ian M. 
Published: September 2020

AbstractUsing the Keynesian model set out in McDonald (2020), in which downward wage rigidity is supported by worker loss aversion with respect to wages, this article shows that a period of social distancing (SD) can leave a post‐SD economy with both stimulatory and depressive effects. A loss of productive capacity is stimulating. Costs of restarting firms, lower labour productivity when restarted and a desire to restore wealth from debt incurred during the period of SD are depressive. If, as seems highly probable, the net effect on economic activity is negative then a fiscal expansion can restore activity. To avoid an increased government budget deficit, this expansion would probably require an increased tax rate. Reductions in real wages may also be necessary. A desire to balance the government budget combined with no increase in the tax rate would be unfortunate, because it would cause a further contraction in activity from its post‐SD level.
The ATO Longitudinal Information Files (ALife): A New Resource for Retirement Policy Research
Authors: Polidano Cain , Carter Andrew , Chan Marc , Chigavazira Abraham , To Hang , Holland Justin , Nguyen Son , Vu Ha , Wilkins Roger 
Published: September 2020

AbstractThe Australian Taxation Office release of annual longitudinally linked individual tax and superannuation records, known as the ATO Longitudinal Information Files (ALife), opens up opportunities for new research. In this study, we provide an overview of ALife, focusing on its use for retirement income research. To this end, we provide the first longitudinal estimates of superannuation outcomes for 1‐year birth cohorts. Results show marked increase in disparity of super balances in the lead‐up to retirement as those in the top quartile ramp‐up their contributions, possibly to take advantage of the favourable tax treatment of superannuation income in retirement years.
The Problem with Provocation in Trespass
Authors: Field Iain D. 
Published: September 2020

AbstractShould a defendant to an action in trespass be entitled to a reduction in compensatory damages on the basis of provocation by the claimant? Judges and academic commentators are divided on the issue, although the weight of authority is that, in Australia, New Zealand and the UK, no such reduction is permissible. This article demonstrates that the reasons conventionally offered in support of the current position are unpersuasive, and that a strong moral argument supports the reduction of damages in many commonplace scenarios. However, the article also shows that the continued rejection of provocation might be justified on the grounds that no principled basis exists upon which to preclude its operation in normatively problematic contexts, such as domestic violence and unwanted sexual advances. It is suggested that the best solution would be for the common law to recognise a partial defence of provocation, subject only to certain principled limitations, leaving it to parliament to ‘carve out’ appropriate policy exceptions.
Healing cultural trauma and its application to the Router programme
Authors: Merchant John 
Published: September 2020

AbstractThis paper explores the issue of cultural trauma, which is an area of concern in psychology generally and has emerged as one within the International Association for Analytical Psychology’s Router training programme. A summary of responses to the issues of cultural trauma and complexes (alongside cultural differences) within analytical psychology are presented, followed by an overview of findings from the IAAP’s evaluation of the Router training programme. These findings are then aligned with contemporary sociological research. The significant issues involved in healing cultural trauma seem to be ‘working through’, as well as the place of imagination, dreamwork, symbolism and metaphor. Research in Poland has specifically highlighted the importance of good governance, economic vitality, personal and social capital (as in education and social participation), a meaning system, certain external contingencies, channels of mobility and ritualism.
Maternal risk of hypertension 7–15 years after pregnancy: clues from the placenta
Authors: Holzman CB , Senagore P , Xu J , Dunietz GL , Strutz KL , Tian Y , Bullen BL , Eagle M , Catov JM 
Published: September 2020

ObjectiveTo assess whether pre‐eclampsia (PE)‐related placental/extraplacental membrane findings are linked to moderately elevated blood pressure (BP) in pregnancy and later‐life hypertension.DesignProspective cohort.Setting52 prenatal clinics, 5 Michigan communities.SampleThe POUCH Study recruited women at 16–27 weeks’ gestation (1998–2004) and studied a sub‐cohort in depth. This sample (n = 490) includes sub‐cohort women with detailed placental assessments and cardiovascular health evaluations 7–15 years later in the POUCHmoms follow‐up study.MethodsPE‐related placental/extraplacental membrane findings (i.e. mural hyperplasia, unaltered/abnormal vessels or atherosis in decidua; infarcts) were evaluated in relation to pregnancy BP and odds of Stage 2 hypertension at follow up using weighted polytomous regression. Follow‐up hypertension odds also were compared in three pregnancy BP groups: normotensives (referent) and moderately elevated BP with or without PE‐related placental/extraplacental membrane findings.Main outcome measuresStage 2 hypertension (SBP ≥140 mmHg and/or DBP ≥90 mmHg, or using antihypertensive medications) at follow up.ResultsAfter excluding women with pregnancy hypertension (i.e. chronic, PE, gestational), mural hyperplasia and unaltered/abnormal decidual vessels were each associated with Stage 2 hypertension at follow up: adjusted odds ratio (aOR) = 2.7, 95% CI 1.1–6.6, and aOR = 1.7 (95% CI 0.8–3.4), respectively. Women with moderately elevated BP in pregnancy and evidence of mural hyperplasia or unaltered/abnormal decidual vessels had greater odds of Stage 2 hypertension at follow up: aOR = 4.5 (95% CI 1.6–12.5 and aOR = 2.6, 95% CI 1.1–5.9, respectively.ConclusionsPE‐related placental/extraplacental membrane findings help risk‐stratify women with moderately elevated BP in pregnancy for later development of hypertension.Tweetable AbstractPlacental findings associated with mother’s risk of later‐life hypertension.
Capsicum annuum(hot pepper): An ancient Latin‐American crop with outstanding bioactive compounds and nutraceutical potential. A review
Authors: Hernández‐Pérez Talía , Gómez‐García María del Rocío , Valverde María Elena , Paredes‐López Octavio 
Published: September 2020

AbstractHot pepper (Capsicum annuum) fruits, usually termed as chili, have been used since ancient times as food vegetables, flavoring ingredients, natural colorants, and in traditional medicines. Nowadays, a wide variation of sweet and pungent peppers are consumed worldwide in a large variety of forms. Interestingly, the most important hot pepper at the global level in commercial terms isC. annuumwith a high number of varieties. This review comparesC. annuumto otherCapsicumspecies for plant agronomic traits, biochemical composition, the content of capsaicin and capsaicinoids and their nutraceutical and medical potentialities, and the effects of processing on quality and key components of the fruit, among other aspects. Chili contains important levels of pigments (i.e., chlorophyll, anthocyanin, and lutein) with potential health benefits; it also contains additional outstanding health‐promoting chemical compounds, such as vitamins, minerals, flavonoids, carotenoids, and capsaicinoids, in general. And capsaicin, the major active compound responsible for the pungent taste of these species has been proven to have a positive role in health. We report here on how dietary chili and capsaicinoids consumption, especially capsaicin, are involved in body weight reduction and their potential antiobesity effects, in urinary disorders, as well as antioxidants, antimicrobial, anticancer, and analgesic capacity. Selected characteristics of processing for the fruit preservation on its quality and content of these compounds are described as well. However, additional clinical research on the mechanism of action and efficacy of frequent capsaicinoid consumption on human health is needed.