bluuebunny/crossref_metadata_2025_split huggingface dataset:
A HAWAII-2RG Infrared Camera Operated Under Fast Readout Mode for Solar Polarimetry
Authors: Hanaoka Yoichiro , Katsukawa Yukio , Morita Satoshi , Kamata Yukiko , Ishizuka Noriyoshi 
Published: July 2020

Abstract
Polarimetry is a crucial method to investigate solar magnetic elds. From the viewpoint of space weather, the magnetic eld in solar laments, which occasionally erupt and develop into interplanetary ux ropes, is of particular interest. To measure the magnetic eld in laments, high-performance polarimetry in the near-infrared wavelengths employing a high-speed, large-format detector is required; however, so far, this has been difficult to be realized. Thus, the development of a new infrared camera for advanced solar polarimetry has been started, employing a HAWAII-2RG (H2RG) array by Teledyne, which has 2048 2048 pixels, focusing on the wavelengths in the range of 1.0{1.6 m. We solved the problem of the difficult operation of the H2RGs under \fast readout mode" synchronizing with high-speed polarization modulation by introducing a \MACIE" (Markury ASIC Control and Interface Electronics) interface card and new assembly codes provided by Markury Scientic. This enables polarization measurements with high frame-rates, such as 29{117 frames per seconds, using a H2RG. We conducted experimental observations of the Sun and conrmed the high polarimetric performance of the camera.
“Bridge over troubled water”: A first look at adolescent psychiatric outpatients transited from regular care to teletherapy during the COVID-19 outbreak using quantitative and qualitative analyses.
Authors: Huscsava Mercedes Maria , Scharinger Christian , Plener Paul L. , Kothgassner Oswald D. 
Published: July 2020

Abstract
BackgroundAdolescents suffering from psychiatric disorders are at risk of disproportionally suffering from the current COVID-19-pandemic. We aimed to assess their specific needs and to evaluate factors influencing a successful transition into teletherapy.MethodsThirty adolescent psychiatric outpatients participated in a series of interviews. The primary outcome was the level of psychosocial functioning. Secondary outcome were potential changes in differential symptom domains. Additionally, answers to open questions were analysed qualitatively.ResultsWithin-group effect size estimates revealed a significant decrease in the level of functioning within the first two months after transition from face-to-face therapy (M = 2·7, SD = 1·258) to teletherapy (M = 3·0, SD = 1·245) (T29 = -2·536, p = 0·017, d = 0·46). Qualitative analysis revealed a marked difference in the level of perceived social support in the subgroup of patients who deteriorated in their level of functioning. Those patients also showed a lower degree of verbal differentiation concerning emotions and affect, as well as a higher degree of introspection and rumination. ConclusionsDespite an overall deterioration, in absolute numbers most patients showed a stagnation in their level of functioning, even if difficulties were expressed. The most prominent difference in the subgroup who showed a decreased level of functioning, was the lack of perceived social support. Provision of strategies to enhance verbalisation and differentiation of emotions and affect might be beneficial.
Molecular Interactions of Fullerene-Based Derivatives and SARS-CoV-2
Authors: Gawad Alaa El-DinA. , Bayoumy Ahmed M. , Ibrahim Medhat A. 
Published: July 2020

Abstract
There are no expedient proven to stop the outbreak of SARS-CoV-2 at this phase. This leads to diversity of endeavors to find out the effective drug or vaccine. One of these possibilities is to exploit the unique characteristics of fullerene-based derivatives. A computer-aided method (molecular docking) was applied to assess the differential binding behavior of these compounds and determining hydrophobic forces, electrostatic interactions, and hydrogen bonds played vital roles in the interactions with SARS-CoV-2 spike protein. The molecular docking calculation clarifies the binding mode and the binding sites may facilitate the development of new or improved therapeutic regimes effective against COVID-19. Fulleropyrrolidine-NH2 seems to be promising candidate for interacting with SARS-CoV-2 binding site.
Jasonsmithite, a new phosphate mineral with a complex microporous framework, from the Foote mine, North Carolina, U.S.A
Authors: Kampf Anthony R. , Celestian Aaron J. , Nash Barbara P. 
Published: July 2020

Abstract
Jasonsmithite (IMA2019-121), Mn42+ZnAl(PO4)4(OH)(H2O)7·3.5H2O, is a pegmatite-phosphate mineral from the Foote Lithium Company mine, Kings Mountain district, Cleveland County, North Carolina, U.S.A. It is interpreted as having formed by late-stage, low-temperature hydrothermal alteration. Crystals are colorless to light brown, slightly flattened prisms to about 1 mm in length with wedge-shaped terminations. The mineral is transparent with vitreous luster, white streak, Mohs hardness 2, brittle tenacity, irregular fracture, and perfect {001} cleavage. The density is 2.63(2) g/cm3. Jasonsmithite is biaxial (–), with α = 1.561(2), β = 1.580(2), γ = 1.581(2), measured in white light. The 2V is 25(5)° and dispersion is r &lt; ν moderate. The optical orientation is Y = b, X ^ c = 18° in obtuse β. The Raman spectrum is dominated by vibrational modes of PO4 and ZnO4 tetrahedra, AlO6 and MnO6 octahedra, and OH groups. Electron microprobe analyses gave the empirical formula (Mn3.09Fe0.87)Σ3.96Zn1.05Al0.98(PO4)4(OH)(H2O)7·3.5H2O. The mineral is monoclinic, P21/c, a = 8.5822(3), b = 13.1770(6), c = 20.3040(14) Å, β = 98.485(7)°, V = 2271.0(2) Å3, and Z = 4. The structure (R1 = 0.0443 for 3685 I&gt;2σI reflections) contains zigzag chains of edge-sharing MnO6 octahedra that corner-link to adjacent chains and to PO4 tetrahedra to form sheets, which are decorated by ZnO4 tetrahedra. The sheets are linked to one another via dimers of AlO6 octahedra, forming a framework with large channels containing H2O groups. With H2O groups removed, the framework has a void space of 70.2% per unit cell, and a framework density of 14.5 polyhedral atoms/1000 Å3, which would place jasonsmithite among the most porous minerals.
A GPU-based 2D shallow water quality model
Authors: Gordillo Geovanny , Morales-Hernández Mario , Echeverribar I. , Fernández-Pato Javier , García-Navarro Pilar 
Published: July 2020

Abstract
In this study, a 2D shallow water flow solver integrated with a water quality model is presented. The interaction between the main water quality constituents included is based on the Water Quality Analysis Simulation Program. Efficiency is achieved by computing with a combination of a Central Processing Unit (CPU) and a Graphics Processing Unit (GPU) device. This technique is intended to provide robust and accurate simulations with high computation speedups with respect to a single-core CPU in real events. The proposed numerical model is evaluated in cases that include the transport and reaction of water quality components over irregular bed topography and dry–wet fronts, verifying that the numerical solution in these situations conserves the required properties (C-property and positivity). The model can operate in any steady or unsteady form allowing an efficient assessment of the environmental impact of water flows. The field data from an unsteady river reach test case are used to show that the model is capable of predicting the measured temporal distribution of dissolved oxygen and water temperature, proving the robustness and computational efficiency of the model, even in the presence of noisy signals such as wind speed.
Synthesis of nanoZrO2 via simple new green routes and its effective application as adsorbent in phosphate remediation of water with or without immobilization in Al-alginate beads
Authors: Biftu Wondwosen Kebede , Ravindhranath Kunta 
Published: July 2020

Abstract
Nano particles of ZrO2 of average size 10.91 nm are successfully synthesized via green routes from a solvent blend of water and ethylene glycol (4:1 v/v). Bio-extract of seeds of Sapindus plant is employed as stabilizing and/or capping agent and homogeneous method of precipitation is adopted to generate the precipitating agent. The nZrO2 particles are immobilized in aluminum alginate beads (nZrO2-Al- alig). Nano-ZrO2 and beads are investigated as adsorbents for the extraction of phosphate from water. The controlling physicochemical parameters are studied for the maximum phosphate removal using simulate water. The optimum conditions are: pH: 7; sorbent dosage: 0.1 g/100 mL for nZrO2 and 0.08 g/100 mL for beads; equilibration time: 30 min.for nZrO2 and 35 min for beads; initial phosphate concentration: 50 mg/L; temperature: 30 ± 1 °C; 300 rpm. The adsorption capacities are: 126.2 mg/g for nZrO2 and 173.0 mg/g for ‘nZrO2-Al- alig’ and they are higher than many reported in literature. The beads, besides facilitating the easy filtration, are exhibiting enhanced cumulative phosphate-adsorption nature of nanoZrO2 and Al-alginate. X-ray diffraction (XRD), Fourier transform infrared (FTIR), field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray (EDX) investigations are employed in characterizing the adsorbents. Of the various isotherm models analyzed to assess the nature of adsorption, Freundlich model provides the best correlation (R2 = 0.99 for nZrO2 and R2 = 0.99 for ‘nZrO2-Al-alig’), indicating the heterogeneous and multi-layered adsorption process. Thermodynamic studies reveal the endothermic and spontaneous nature of sorption. Pseudo-second-order model of kinetics describes the adsorption well. Spent adsorbents can be regenerated with marginal loss of adsorption capacity until five cycles. The sorbents are successfully applied to remove phosphate from polluted lake water samples.
PLGA Nanoparticles for Nose to Brain Delivery of Clonazepam: Formulation, Optimization by 32 Factorial Design, In Vitro and In Vivo Evaluation
Authors: Shah Pranav , Sarolia Jayant , Vyas Bhavin , Wagh Priti , Ankur Kaul , Kumar Mishra Anil 
Published: July 2020

Background:Intranasal administration of biodegradable nanoparticles has been extensively studied for targeting the drug directly to CNS through olfactory or trigeminal route bypassing blood brain barrier.Objective:The objective of the present study was to optimize Clonazepam loaded PLGA nanoparticles (CLO-PNPs) by investigating the effect of process variables on the responses using 32 full factorial design.Methods:Effect of two independent factors-amount of PLGA and concentration of Poloxamer 188, were studied at low, medium, and high levels on three dependent responses-%Entrapment efficiency, Particle size (nm), and % cumulative drug release at 24hr.Results:%EE, Particle size, and %CDR at 24hr of the optimized batch was 63.7%, 165.1 nm, and 86.96%, respectively. Nanoparticles were radiolabeled with99mTc and biodistribution was investigated in BALB/c mice after intranasal and intravenous administrations. Significantly higher brain/blood uptake ratios and AUC values in the brain following intranasal administration of CLO-PNPs indicated more effective brain targeting of CLO. Higher brain uptake of intranasal CLO-PNPs was confirmed by rabbit brain scintigraphy imaging. A histopathological study performed on goat nasal mucosa revealed no adverse response of nanoparticles. TEM image exhibited spherical shaped particles in the nano range. DSC and XRD studies suggested Clonazepam encapsulation within the PLGA matrix. The onset of occurrence of PTZ-induced seizures in rats was significantly delayed by intranasal nanoparticles as compared to intranasal and intravenous CLO-SOL.Conclusion:This investigation exhibits rapid rate and higher extent of CLO transport in the brain with intranasal CLO-PNPs suggesting a better option as compared to oral and parenteral route in the management of acute status epilepticus.
Analisis Implementasi Kebijakan Program Pengendalian Resistensi Antimikroba (PPRA)
Authors: Rukmini Rukmini , Siahaan Selma , Sari Ida Diana 
Published: July 2020

Antimicrobial resistance has become a problem in Indonesia. The Ministry of Health has established a policy ofAntimicrobial Resistance (AMR) Control Program in hospitals to resolve the issue. A qualitative case study was conducted at Dr. RSUP Wahidin Sudirohusodo hospital, Makassar in 2018 to analyze the implementation of AMR control program. The data were collected through in-depth interviews and analyzed descriptively. The study showed that policy AMR control program has not be carefully implemented. The function of AMR control program team is to make policies and guidelines for antibiotic use, to make surveillance of germ patterns and antibiotic sensitivity, clinical audits of antibiotic use, to conduct studies/research and to make evaluation that is reported to the Hospital Director. However, this AMR control program has not been optimally implemented due to many challenges such as lack of budget, lack of commitment and internal coordination between the AMR control program team members. Implementation of AMR control program in this hosptal management is not optimal. The Program dissemination and AMR team activities were not evenly distributed. High workload, inadequate infrastructure and antibiotic resistance issues of the referred patients. As a conclusion AMRcontrol program policy in RSUP. Wahidin Sudirohusodo, Makassar, has not been properly disseminated and implemented. Coordination, dissemination and discussion forums on PPRA policies internally and externally with cross-sectoral hospitals are needed to improve antimicrobial resistance control commitment.
The Association Between HbA1c and Time in Hypoglycemia During CGM and Self-Monitoring of Blood Glucose in People With Type 1 Diabetes and Multiple Daily Insulin Injections: A Randomized Clinical Trial (GOLD-4)
Authors: Seyed Ahmadi Shilan , Westman Klara , Pivodic Aldina , Ólafsdóttir Arndís F. , Dahlqvist Sofia , Hirsch Irl B. , Hellman Jarl , Ekelund Magnus , Heise Tim , Polonsky William , Wijkman Magnus , Schwarcz Erik , Lind Marcus 
Published: July 2020

OBJECTIVE
According to recent guidelines, individuals with type 1 diabetes should spend &lt;4.0% of time per day with glucose levels &lt;3.9 mmol/L (&lt;70 mg/dL) and &lt;1.0% per day with glucose levels &lt;3.0 mmol/L (&lt;54 mg/dL).

RESEARCH DESIGN AND METHODS
In the GOLD randomized crossover trial, 161 individuals with type 1 diabetes treated with multiple daily insulin injections (MDI) were randomized to continuous glucose monitoring (CGM) or conventional therapy with self-monitoring of blood glucose (SMBG) and evaluated over 16 months. We estimated the association between time spent in hypoglycemia and various mean glucose and HbA1c levels.

RESULTS
Time spent in hypoglycemia (&lt;3.9 mmol/L and &lt;3.0 mmol/L) increased significantly with lower mean HbA1c and mean glucose levels during both CGM and conventional therapy. During CGM, 24 (57.1%) individuals with HbA1c &lt;7.5% (&lt;58 mmol/mol) had &lt;1.0% time spent in hypoglycemia &lt;3.0 mmol/L and 23 (54.8%) had &lt;4.0% time spent in hypoglycemia &lt;3.9 mmol/L. During CGM, mean time spent in hypoglycemia for individuals with mean HbA1c 7.0% (52 mmol/mol) was estimated to be 5.4% for &lt;3.9 mmol/L and 1.5% for &lt;3.0 mmol/L. The corresponding values during SMBG were 9.2% and 3.5%, respectively. Individuals with mean glucose levels of 8 mmol/L spent 4.9% units more time with glucose levels &lt;3.9 mmol/L and 2.8% units more time &lt;3.0 mmol/L during SMBG compared with CGM.

CONCLUSIONS
Reaching current targets for time in hypoglycemia while at the same time reaching HbA1c targets is challenging for patients with type 1 diabetes treated with MDI both with CGM and SMBG monitoring. However, CGM is associated with considerably less time in hypoglycemia than SMBG at a broad range of HbA1c levels and is crucial for patients with MDI treatment if they are to have a chance to approach hypoglycemia targets.
EFFECT OF ENRICHED SANJEEVANI AND AGNIHOTRA ON GROWTH, YIELD AND QUALITY OF BRINJAL (Solanum melongena L.)
Authors: Tripathy Saswatik , Dutta Avijit Kr. 
Published: July 2020

Brinjal is a crop grown widely all over India and preferred by both rich and poor. The Chhotanagpur plateau of Jharkhand is famous for quality vegetable production and brinjal is very commonly grown in this region almost throughout the year. However, the most of the commercial growers using plant protection chemicals and synthetic fertilizers those are so expensive that poor farmers can’t afford. The extensive uses of agro-chemicals and synthetic fertilizers also reduce the quality of both the produce and the cultivated soil. In this context, an attempt has been made through the present investigation by growing different varieties of brinjal by adopting Vedic (Enriched Sanjeevani) Farming and Homa Induction (Agnihotra) techniques with their respective four non-chemical alternative growing approaches, viz. E1C1: Enriched Sanjeevani (1%), E1C2: Absolute Control (inherent fertility status of the experimental plot); E2C1: Enriched Sanjeevani (1%) + Homa Induction (Agnihotra), and E2C2: Only Homa Induction (Agnihotra). Five varieties of the crop, viz. V1: Swarna Pratibha; V2: Swarna Neelima; V3: Swarna Shakti; V4: Mukta Jhuri; V5: Long Green were grown with their four replications under four growing conditions and the Randomized Completed Block Design was adopted for field trials. Different growth, yield and quality attributing characters of the crop were taken into account and findings revealed that E2C1: Enriched Sanjeevani (1%) + Homa Induction (Agnihotra) was the most suitable growing condition for V2 (Swarna Neelima) with the maximum yield (72.37 t ha-1). Different growth and yield attributes of the crop varieties (especially in the case of V2: Swarna Neelima) were highly influenced by Enriched Sanjeevani (1%) + Homa Induction (Agnihotra) [E2C1] growing condition resulting higher benefit cost ratio of 6.78. Quality contributing attributes were also highly influenced by homa induction (Agnihotra), as a consequence, higher level of dry matter, TSS, and ascorbic acid contents were estimated from almost all samples collected from E2C1: Enriched Sanjeevani (1%) + Homa Induction (Agnihotra), and E2C2: Only Homa Induction (Agnihotra) growing conditions.
PROMOSI GIZI MELAUI METODE EMO DEMO UNTUK MERUBAH PERSEPSI IBU TENTANG MAKANAN JAJANAN BERBASIS PANGAN LOKAL
Authors: Hidayanti Lilik 
Published: July 2020

High consumption of food snacks can cause decreased of food intake of children aged 0-5 years. It is due to the children feel full so they refuse meal. Impact of this behaviour is decreasing level of energy adequacy and level of protein adequacy so eventually decreasing their nutritional status. Food snacks contain much of sucrose and salt but a little protein. In addition food snack often contains food additives and also not guaranteed of its safety. To solve this problem, mothers can make food snack by themselves from local foods. Promoting local food is very important to introduce and to increase of understanding of mother about composition and nutritional contain of local food. The aim of this activity was changing mother perception about used of local foods (breadfruit and Tilapia fish) as raw materials of food snack for children aged 0-5 years. This activity used Emo Demo method with theme “cheap food snack, Rich of nutrition”. Subjects were 30 mothers who had child aged 0-5 years and also always came to Posyandu in Sukarame, Tasikmalaya. Change of perception was measured by comparing pre test and post test results,and wilcoxon was used to analyze the difference of pre test and post test results. Mean of pre test score was 9,2 and post test score was 12,9. The result of wilcoxon test shown there was the difference of pre test and post test (p < 0,001). Based on this activity, the suggestion was to continue this activity with training so the subjects were able to make foods snack using local foods (Breadfruit and Tilapia fish) as raw materials.
FAKTOR-FAKTORYANG MEMPENGARUHI KESEJAHTERAAN HIDUP MASYARAKAT SUKU LAUT PULAU BERTAM KOTA BATAM
Authors: Sari Meri Enita Puspita , Pratiwi Diah Ayu 
Published: July 2020

Pemerintah Kota Batam telah melaksanakan berbagai usaha untuk meningkatkan kesejahteraan hidup dikalangan komunitas suku laut. Berbagai program, pelatihan dan pendidikan keterampilan telah dilakukan oleh pemerintah kepada Suku Laut ini untuk meningkatkan keterampilan dasar mereka, namun program-program yang dilaksanakan masih belum mampu meningkatkan keterampilan-keterampilan dasar yang diperlukan dalam kehidupan Suku Laut. Penelitian ini menggunakan metode penelitian kualitatif, metode ini digunakan untuk dapat menggambarakan dan mengkaji faktor-faktor yang mempengaruhi tingkat kesejahteraan masyarakat suku laut Pulau Bertam. Berdasarakan hasil penelitian, Perubahan hidup yang dijalankan oleh masyarakat suku laut pulau Bertam mempengaruhi kualitas hidup mereka terutama kesejahteraan sosial. komunitas Suku Laut masih bergantung kepada hasil tangkapan ikan secara tradisional saja dan hidup dalam kondisi yang serba kekurangan, hal tersebut terlihat dari kualitas air yang diperoleh, rumah yang ditempati dan peralatan tangkapan ikan yang belum memadai, diaspek sosial lainnya komunitas masyarakat Suku Laut didapati masih tidak melakukan aktivitas kemasyarakatan secara bersama antara satu sama lain. Selain faktor agama yang berbeda, masyarakat lebih banyak berkumpul dengan keluarga masing-masing dibanding berbaur dengan masyarakat lainnya yang lain. Aspek budaya juga mempengaruhi perubahan hidup masyarakat Suku laut. Hal ini terlihat dari mulai pudarnya budaya tradisi dalam hal kesenian dan generasi yang ada akan berhadapan dengan beberapa ancaman seperti kehilangan identitas Suku Laut sebagai penangkap ikan, kesulitan meneruskan kehidupan karana masyarakat mereka masih berada dalam tingkat pendidikan yang sangat rendah dan tidak mampu bersaing dalam dunia yang semakin berkembang.
Hypoglycemia in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Prospective Observational Study
Authors: Hong Susana , Presswala Lubaina , Harris Yael T. , Romao Isabela , Ross Daniel W. , Andrade Paz Hugo , Zhang Meng , Jhaveri Kenar D. , Sakhiya Vipul , Fishbane Steven 
Published: July 2020

Background
Glycemic management in patients with type 2 diabetes mellitus (T2DM) and CKD can become complicated. One factor that may affect treatment is hypoglycemia. Hypoglycemia risk may be increased by several biologic processes in CKD. The objective of this study was to determine the frequency, severity, and risk factors for hypoglycemia in patients with T2DM and CKD.

Methods
The design was a prospective observational study. A continuous glucose monitor (CGM) was worn by 80 patients for up to 14 days; glucose was measured every 15 minutes. Patients with T2DM and eGFR <45 ml/min were enrolled. Patients on dialysis were excluded. The primary outcome was to assess the frequency of hypoglycemic episodes during the study period. Hypoglycemic episodes were defined as a reduced glucose concentration (<70 mg/dl) lasting ≥15 minutes. Secondary outcomes included assessment of severity of hypoglycemia and risk factors for its development.

Results
A total of 80 patients wore the CGM for a mean of 12.7±2.9 days. Hypoglycemic events occurred in 61 of 80 patients (76%) with glucose <70 mg/dl, and 49 of 80 (61%) with glucose <60 mg/dl. Prolonged hypoglycemic events (CGM glucose <54 mg/dl for ≥120 consecutive minutes) occurred in 31 patients (39%) with 118 total events. Most hypoglycemic episodes occurred overnight, from 1:00 am to 9:00 am. By multivariate analysis, lower hemoglobin A1c and treatment with insulin were two modifiable risk factors for hypoglycemic events.

Conclusions
Patients with T2DM and CKD have frequent periods of hypoglycemia that can be severe and prolonged. Hemoglobin A1c does not portray the full scope of hypoglycemia risk. This study illustrates the need for careful monitoring of glucose levels in patients with T2DM and CKD.