bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pertussis in the Voronezh Region: Epidemiology and Vaccination
Authors: Mamchik N. P. , Gabbasova N. V. , Sitnik T. N. , Steinke L. V. 
Published: November 2020

Relevance. In recent years, the increase in the incidence of pertussis has been observed in many countries despite high vaccination coverage of the child population.Purpose: was to study the epidemiological features of whooping cough in the Voronezh region for the period from 2008 to 2018 years.Methods. The research material was data the annual form No. 2, 5, 6 of Rosstat for 2008 through 2018. Statistical data processing was performed using Microsoft Excel 2007.Results. The epidemiological features of pertussis in the Voronezh region for the period from 2008 to 2018 have been studied. Despite the high coverage of preventive vaccinations in children of the first years of life, in recent years, the incidence of pertussis increased the average Russian rates by 3,5 times. In the age structure of the diseased there was a tendency to increase the proportion of schoolchildren and adults. Analysis of the reports showed that half of the cases were vaccinated at the prescribed age, but the interval after vaccination before the illness was an average of 9 years.Conclusions. In recent years, there has been a tendency to an increase in the incidence of whooping cough in the Voronezh region. The incidence of vaccinated indicates the natural extinction of post-vaccination immunity to school age and requires a decision on the introduction of revaccination of schoolchildren with actual acellular vaccines.
Evaluation of the Incidence of Rotavirus Infection and the Effectiveness of Vaccination in the Khanty-Mansi Autonomous Ugra District in 2014–2018
Authors: Girina A. A. , Petrovskiy F. I. , Sosykina N. V. , Zaplatnikov A. L. 
Published: November 2020

Relevance. Rotavirus infection (RVI) is recognized as the main cause of severe gastroenteritis in children worldwide and leads to 527 000 deaths annually.Aim. Present study was intended to evaluate the effectiveness of anti-epidemic measures and vaccination against RVI in children in Pyt-Yakh, Khanty-Mansiysk Autonomous Okrug-Ugra in 2016–2017.Materials and methods. An analysis of the incidence of intestinal infection and RVI was carried out within 2 years prior (2014–2015) to and 2 years after (2016–2017) the implementation of anti-epidemic measures.A separate study was conducted to evaluate the safety and efficacy of a live oral pentavalent vaccine in 593 children including 433 who received three doses of the vaccine in 2016–2017.Results. It was shown that anti-epidemic measures including vaccination decreased the chances of RVI in children aged 0–17 years 1.68 fold in 2017–2018 compared to 2015–2016 (odds ratio (OR) 0.59, 95% confidence interval (CI) 0.49–0.71, p < 0.001). The same data were obtained for children 12 months and younger (OR 0.57, 95% CI 0.35–0.95, р = 0.037) and children aged 1–2 years old (OR 0.62, 95% CI 0.45–0.84, р = 0.002). There were no cases of moderate or severe intestinal infections or hospitalizations in vaccinated population as well as postvaccinal complications.Conclusion. The incidence of intestinal and rotavirus infections in all population in 2018 compared to 2016decreased by 53% and 72% respectively.
„Przypomnij sobie…” (Ap 2,5; 3,3) Duch Święty żywą pamięcią Kościoła w świetle Apokalipsy Janowej
Authors: Podeszwa Paweł Adam 
Published: November 2020

Duch Święty przypomina Kościołowi wszystko, co powiedział i uczynił Jezusa. Dwa teksty z Apokalipsy Janowej wskazują wyraźnie na tę funkcję Parakleta, który mówi do wspólnoty, odwołując się jednocześnie do jej pamięci: w Liście do Kościoła w Efezie (2,5) oraz w Liście do Kościoła w Sardach (3,3). Oba pisma zawierają imperatyw „przypomnij sobie”. W ich świetle staramy się odpowiedzieć na podstawowe pytanie: o czym Duch Święty przypomina Kościołowi? Analizowane teksty, w których Duch Święty wzywa wspólnotę Kościoła do pobudzenia pamięci, wyraźnie wskazują, że chodzi przede wszystkim najpierw o przypomnienie fundamentów chrześcijańskiej wiary (wcielenie, misterium paschalne) oraz tożsamości chrześcijan, przez chrzest złączonych z ukrzyżowanym i zmartwychwstałym Jezusem i zrodzonych do nowego życia. Wezwanie do pamiętania jest równoznaczne z koniecznością gorliwego strzeżenia depozytu wiary oraz nawracania się, to znaczy przyjmowania mentalności i zamysłu samego Boga, co dalej ma owocować konkretnymi czynami wiary. Motywacją do takiej postawy chrześcijan jest pamięć o dobrodziejstwach i darach Boga. Duch Święty, nazywany przez Katechizm Kościoła Katolickiego „żywą pamięcią Kościoła” (1099), pobudzając i aktywując pamięć wspólnoty, mobilizuje do żywej i owocującej wiary, która wyraża się w prawdziwym chrześcijańskim świadectwie przynależności do Jezusa, braterskiej miłości oraz gorliwym głoszeniu Dobrej Nowiny.
Danuta Piekarz, (Nie) święty gniew. Co Biblia mówi o złości? (Kraków: Wydawnictwo WAM 2019)
Authors: Bąk Tomasz Bartłomiej 
Published: November 2020

Recenzja książki: Danuta Piekarz, (Nie) święty gniew. Co Biblia mówi o złości? (Kraków: Wydawnictwo WAM 2019). Ss. 168. PLN 24,90. ISBN 978-83-277-1642-2.
The Effect of Intestinal Natural Micro Flora Removal on Susceptibility to Have Seizure in Male Wistar Rats
Authors:   Department of Biology, Faculty of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, Iran., Tahmasebi Saeed , Oryan Sharbanoo ,   Department of Animal Biology, Faculty of Biological Science, University of Kharazmi, Tehran, Iran., Mohajerani Hamid Reza ,   Department of Microbiology, Faculty of Basic Science, Arak Branch, Islamic Azad University, Arak, Iran., Akbari Neda ,   Department of Microbiology, Faculty of Basic Science, Arak Branch, Islamic Azad University, Arak, Iran., Palizvan Mohammad Reza ,   Department of Physiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Published: November 2020

Background and Aim: Epilepsy is a common brain disorder. Brain function can be affected by the intestinal microflora. The intestinal microflora have a major role in modulating immune responses, producing essential metabolites and mediating neurotransmitters. Antibiotics can affect and reduce these roles and functions by eliminating the intestinal microflora. The aim of this study was to investigate the effect of intestinal natural micro flora removal on seizure susceptibility and seizure behavior modification with the use of probiotics in male Wistar rats. Methods & Materials: This study was performed on 32 male Wistar rats with weight range 200-250 gr. The animals were randomly divided into four groups: 1. Control group; 2. Antibiotic group; 3. Probiotic group and 4. Antibiotic + probiotic group. To remove the microflora, antibiotics (neomycin, ampicillin, and metronidazole) for three weeks and for replacement of microflora, probiotics (Lactobacilli casei, Lactobacillus acidophilus and Bifidobacterium bifidum) for four weeks were administered. Seizures were performed by intraperitoneal injection of pentylentrazole. The microflora was examined by the MRS Agar medium and the Pure Plate method. The data were statistically analyzed in Graph Pad Prism V. 8. Ethical Considerations: This study was approved by the Research Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1395.176). Results: The use of antibiotics lead to decrease the number of intestinal bacteria (P<0.0001), increased the severity and stability of seizure stages (P<0.05) and decreased the time delay of seizure onset (P<0.05) compared to the control group. Probiotic consumption by modifying the intestinal microflora (P<0.0001) reduced the severity of seizure and increased the time delay of seizure onset (P<0.05). Conclusion: Elimination of microflora has the potential to induce seizures, which can be compensated by administration of probiotics.
Low Vitamin D Levels Increase the Risk of Early Onset Neonatal Sepsis
Authors: Yuyun Lisnawati , Sungkar Ali , Rohsiswatno Rinawati , Wibowo Noroyono , Hermartin Denni , Kindi Agustin 
Published: November 2020

Abstract
Objective: To identify the association between maternal and umbilical cord vitamin D levels with suspects of early-onset of neonatal sepsis (EONS) in newborns from mothers with preterm premature rupture of membranes (PPROM).Methods: This is a retrospective cohort study conducted from January 2017 to Augusts 2018. Data was taken consecutively from medical records and previous study data at Dr. Cipto Mangunkusumo and Persahabatan Hospital, Jakarta.Results: From total of 72 infants from mothers with PPROM, 22 infants (31%) were EONS-suspected and 50 infants (69%) were not EONS-suspected. There was a significant association between maternal and umbilical cord vitamin D levels with EONS.Conclusion: There was a significant association between maternal and umbilical cord vitamin D levels with EONS.Keywords: early-onset neonatal sepsis, preterm premature rupture of membrane, vitamin D,

Abstrak
Tujuan: Untuk mengetahui hubungan antara kadar vitamin D maternal dan tali pusat dengan risiko tejadinya Sepsis Neonatal Awitan Dini (SNAD) pada bayi dari ibu dengan Ketuban Pecah Dini (KPD).Metode: Desain penelitian kohort retrospektif secara consecutive sampling. Data diambil dari rekam medis dan data penelitian sebelumnya di Rumah Sakit Umum Pusat Nasional (RSUPN) Dr. Cipto Mangunkusumo dan Rumah Sakit Umum Pusat (RSUP) Persahabatan, Jakarta. Hasil: Dari 72 bayi yang dilahirkan dari ibu dengan KPD, 22 bayi (31%) diantaranya diduga mengalami SNAD, sedangkan 50 bayi lainnya tidak mengalami SNAD. Terdapat hubungan yang bermakna antara kadar vitamin D maternal dan tali pusat dengan kejadian SNAD. Kesimpulan:Terdapathubungan yang bermakna antara kadar vitamin D maternal dan tali pusat dengan kejadian SNAD.Kata kunci: ketuban pecah dini, sepsis neonatal awitan dini, vitamin D
Accuracy Tests of Serum Vitamin D and Calcium Levels in Chorioamnionitis
Authors: C. Husna Muhammad F. , Lestari Peby M. , Syamsuri Ahmad K. , Theodorus  
Published: November 2020

Objective: To compare the sensitivity and specificity of the diagnosis of chorioamnionitis in preterm labor using serum vitamin D and calcium in Dr.Mohammad Hoesin Hospital Palembang.Method: This diagnostic test was carried out in the Obstetrics and Gynecology Department of Dr. Mohammad Hoesin Hospital Palembang from October 2018 to April 2019. Research subjects were women in preterm labor with chorioamnionitis. We collected 39 samples and 36 of them met the inclusion criteria.Results: Eighteen patients with hypovitaminosis vitamin D had chorioamnionitis with a sensitivity value of 94.74%, specificity 5, 88%, positive predictive value (PPV) 52.9% and negative predictive value (NPV) 50%. Two of the 4 patients with hypocalcemia had chorioamnionitis with sensitivity of 10.53%, specificity 88. 24%, positive predictive value (PPV) 50% and negative predictive value (NPV) 46. 9%.Conclusion: Reliability of diagnosis accuracy of serum vitamin and calcium levels against chorioamnionitis is poor.Keywords: accuracy tests, calcium, chorioamnionitis, vitamin D
Abstrak
Tujuan: Membandingkan sensitivitas dan spesifisitas diagnosis korioamnionitis pada partus prematurus antara serum vitamin D dan kalsium di Rumah Sakit Dr. Mohammad Hoesin Palembang.Metode: Uji diagnostik dilakukan di Departemen Obstetrik dan Ginekologi RSUP Dr. Mohammad Hoesin Palembang. Penelitian dilaksanakan sejak Oktober 2018 hingga April 2019. Subjek penelitian adalah wanita hamil prematur yang didiagnosa korioamnionitis. Terdapat 39 sampel dimana 36 sampel termasuk kriteria inklusi.Hasil: Terdapat 18 pasien dengan hipovitaminosis vitamin D memiliki luaran koriaoamnionitis memiliki nilai sensitivitas 94,74%, spesifisitas 5, 88%, positive predictive value (PPV) 52, 9% dan negative predictive value (NPV) 50%. 2 dari 4 pasien dengan hipokalsemia memiliki luaran korioamnionitis memiliki sensitivitas 10, 53%, spesifisitas 88, 24%, positive predictive value (PPV) 50% dan negative predictive value (NPV) 46, 9%.Kesimpulan: Akurasi diagnosis kadar serum vitamin dan kalsium terhadap luaran korioamnionitis memiliki derajat kesesuaian (realiabilitas) kurang baik.Kata kunci: kalsium, korioamnionitis, uji kesesuaian, vitamin D
Blood Transfusion in Obstetric Cases
Authors: Sungkar Ali , Surya Raymond 
Published: November 2020

Objective: To discuss about blood loss in an obstetric setting, the role of blood transfusion, and patient blood management.Methods: Literature review.Results: Severe anaemia with hemoglobin level less than 7 g/dL or late gestation (more than 34 weeks) and/ or significant symptoms of anaemia, the recommendation is giving only single unit transfusion followed by clinical reassessment for further transfusion. In postpartum hemorrhage (PPH), massive transfusion protocols are commonly used description as large volume of blood products over a brief period to a patient with uncontrolled or severe hemorrhage, transfusion more than 10 RBC units within 24 hours, transfusion more than 4 RBC units in 1 hour with anticipation of continued need for blood, replacement of more than 50% of total blood volume by blood products within 3 hours. All obstetric units have a clear-cut massive transfusion protocol for the initial management of life-threatening PPH, considering early transfusion therapy with RBCs and FFP.Conclusion: Patient blood management aims to maintain hemoglobin concentration, optimize haemostasis, and minimize blood loss in effort to improve patient outcomes. Massive transfusion protocol in management of life-threatening should depend on each obstetric unit.Keywords: blood transfusion, obstetric cases, patient blood management.

Abstrak
Tujuan: Untuk mendiskusikan tentang hilang darah dalam obstetric, peran transfusi darah, dan patient blood management.Metode: Kajian pustaka.Hasil: Anemia berat dengan nilai hemoglobin kurang dari 7 g/dL atau kehamilan lanjut (lebih dari 34 minggu) dan/ atau gejala nyata anemia, rekomendasi ialah memberikan satu unit transfusi diikuti dengan penilainan klinis untuk transfusi lebih lanjut. Pada perdarahan postpartum, protokol transfusi massif umum digambarkan sebagai volume darah yang dibutuhkan jumlah banyak dalam periode singkat, transfusi lebih dari 10 sel darah merah dalam 24 jam atau lebih dari 1 jam, penggantian lebih dari 50% total volume darah dalam 3 jam. Seluruh unit obstetric memiliki protokol transfusi massif yang jelas untuk taalaksana awal perdarahan postpartum dengan mempertimbangkan transfusi awal untuk komponen sel darah merah dan FFP.Kesimpulan: Patient blood management bertujuan untuk menjaga konsentrasi hemoglobin, optimalisasi hemostasis, dan minimalisasi hilang darah untuk meningkatkan luaran pasien. Protokol transfusi masfi dalam tatalaksana yang mengancam nyawa sangat bergantung pada setiap unit obstetrik.Kata kunci: kasus obstetri, patient blood management, transfusi darah
The Role of Giving High Dose Calcium for Preventing Preeclampsia
Authors: Prasojo Arief K. , Lestari Peby M. , Ansyori Hatta , Theodorus  
Published: November 2020

AbstractObjective: Knowing the effectiveness of high doses of calcium in preventing preeclampsia.Methods: Experimental analytical study with Randomized Controlled design Single-blind trial in the form of survival analysis (survival analysis) in the period June 2018 - May 2019 in fetomaternal outpatients clinic in Mohammad Hoesin Hospital, PalembangResults: The mean hemoglobin level at the last visit found that the average hemoglobin level between the two groups was 12.81 in the high calcium group and 12.61 in the low calcium group, while the mean hematocrit level between the two groups was 35.17 in the high calcium group and 34.84 in the low calcium group and the respective calcium levels each group is 10.1. In this study, after high calcium intervention, no pregnant women with preeclampsia were found, whereas in the low-dose calcium intervention group it was found that 3 of 17 patients (17.7%) had preeclampsia. With the McNemar test it was found that there was no difference in the incidence of preeclampsia both after highdose calcium and low-dose calcium interventions (p = 0.250).Conclusions: High-dose calcium (1.5g - 2g) is effective in preventing preeclampsia and there was no difference in effectiveness between administration of high-dose calcium with low-dose calcium administration to the incidence of preeclampsia.Keywords: high dose calcium, preeclampsia, randomized control trial.
AbstrakTujuan: Mengetahui efektivitas pemberian kalsium dosis tinggi dalam mencegah preeklamsia.Metode: Penelitian analitik eksperimental dengan desain randomized controlled trial single blind dalam bentuk ujian alias kesintasan (survival analysis) dalam kurun waktu Juni 2018 – Mei 2019 di Poliklinik Fetomaternal Rumah Sakit Umum Pendidikan Mohammad Hoesin, PalembangHasil: Rerata kadar hemoglobin pada kunjungan terakhir didapatkan rerata kadar hemoglobin antara kedua kelompok adalah 12,81 pada kelompok kalsium tinggi dan 12,61 pada kelompok kalsium rendah, sedangkan rerata kadar hematokrit antara kedua kelompok adalah 35,17 pada kelompok kalsium tinggi dan 34,84 pada kelompok kalsium rendah dan rerata kadar kalsium masing-masing kelompok adalah 10,1. Pada penelitian ini setelah intervensi kalsium tinggi tidak ditemukan ibu hamil yang mengalami preeklamsia, sedangkan pada kelompok intervensi kalsium dosis rendah ditemukan 3 dari 17 pasien (17,7%) menderita preeklamsia. Dengan uji Mc Nemar didapatkan hasil tidak terdapat perbedaan kejadian preeklamsia baik setelah intervensi kalsium dosis tinggi maupun kalsium dosis rendah (p = 0,250). Hal ini berarti kalsium dosis tinggi dan rendahefektif untuk mencegah preeklamsia.Kesimpulan: Kalsium dosis tinggi (1,5g – 2g) efektif dalam mencegah preeklamsia dan tidak ditemukan perbedaan efektivitas antara pemberian kalsium dosis tinggi dengan pemberian kalsium dosis rendah terhadap kejadian preeklamsia.Kata kunci: kalsium dosis tinggi, preeklamsia, randomized control trial.
Clavicle Morphometry for Sexual Dimorphism and Bilateral Asymmetry: Radiographic Assessment
Authors: KC Sudikshya , Shrestha Subina , Acharya Sumnima , Bhandari Keshav Raj 
Published: November 2020

Background: The clavicle, modified long bone, presents morphological and bilateral variations. This may be due to genetic factors, hormones, or environmental and occupational influences. Anthropometric studies in clavicle of Nepalese population using radiograph has not been reported to best of our knowledge. This study, aimed to determine the sexual dimorphism and bilateral asymmetry of clavicle in Nepalese Population using Postero-Anterior Chest X Ray.
Methods: Chest x-rays with normal and clearly visible both clavicles of 1260 Nepalese adults (591 male, 669 female), aged above 20 years were utilized. Inbuilt software “Computed Radiography Fuji Computer System 7” was used for measurements (in centimeter) of sternal head length, acromial end length, mid shaft diameter and length of clavicle. Demarcating point and identification point were calculated. Patients having history of clavicles fractures in the past were excluded.
Results: All the parameters in male is greater than female which is significant except Length/Mid Shaft Diameter. Similarly, all the parameters of right clavicle is significantly greater than left clavicle in both sexes except Sternal Head Length and Mid Shaft Diameter. Demarcating point calculated from length of the clavicle (right >16.17, left >16.10 for male and right <11.20, left <10.65 for female) and Mid Shaft Diameter (right >1.33, left >1.38 for male and right <0.66 and left <0.67 for female) are important parameters to determine sex.
Conclusions:The clavicle shows significant sexual dimorphism and bilateral asymmetry in Nepalese population. The result of this study is helpful to anthropologist and forensic medicine.
Keywords: Anthropometry; clavicle; demarcating point; postero-Anterior chest x-rays; sexual dimorphism
Depression and Quality of Life among the Chronic Kidney Disease Patients
Authors: Kunwar Dipak , Kunwar Rajyashree , Shrestha Barsha , Amatya Richa , Risal Ajay 
Published: November 2020

Background: Depression and other mental illness are very common among chronic kidney disease and also Quality of life has been found significantly impaired in chronic kidney disease. The objective of our study is to study Depression, Quality of life and its associations in chronic kidney disease.
Methods: This was a descriptive cross-sectional study. We used convenient method of sampling for data collection. The World Health Organization Quality-of-Life 8-question scale was used for estimating quality of life and Beck Depression Inventory was used for the assessment of depression. Independent samples t-test was conducted to analysed bivariate relationship of sociodemographic factors with depression and Quality of life scores and multiple linear regression analysis was performed to determine predictors of Quality of life.
Results: The 75.5% participants found to have depression. Depression was found statistically significant across socioeconomic status (p value 0.04) and other medical comorbidities (p value 0.04). Variables found to be significantly associated with total quality of life in multiple linear regression analysis were caste (p value 0.03), socioeconomic status (p value 0.009) and depression (p value 0.001).
Conclusions: Depression and reduced quality of life is very common among chronic kidney patients. Low socioeconomic status and comorbid medical conditions were associated with depression and caste, low socioeconomic status and depression were associated with low quality of life. Screening and management of depression should be included in the routine care and it could help improving the quality of life of patients with chronic kidney disease.
Keywords: chronic kidney disease; depression; quality of life
Pattern of Vaginal Birth after Cesarean, its Variables and Outcome at the Interval of One Decade in Dhulikhel Hospital
Authors: Tamrakar Suman Raj , Timilsina Neeta 
Published: November 2020

Background: There should be high index of suspicion for timely detection of any complications for safe trial of labor in case of vaginal birth after cesarean. Emergency obstetric care must be available. Even with these provisions the vaginal birth after cesarean rate is decreasing in Dhulikhel Hospital in recent years.
Methods: This retrospective study was conducted to compare different modes of delivery and pattern vaginal birth after cesarean in a gap of ten years in Dhulikhel Hospital (i.e. 2007 to 2009 versus 2017 to 2019). In this study factors associated with the successful vaginal birth after cesarean were also analyzed.
Results: A total of 4215 deliveries conducted in the year 2007 to 2009, of them 890 (21.1%) were cesarean deliveries. Likewise altogether 9298 deliveries conducted in the year 2017 to 2019, of them 2849 (30.6%) were cesarean deliveries. Vaginal birth after cesarean rate is significantly decreased from 18.33% (33/180) to 8.8% (63/713) (p value = 0.0004). Instrumental deliveries, normal vaginal deliveries were significantly decreased in comparison to these in the year 2007 to 2009. Duration of labor of vaginal birth after cesarean (7.05±1.25 vs 7.13±2.02, p=0.8362) and mean fetal weight of vaginal birth after cesarean baby (2818.71±686.37 vs 2820.79±511.78, p=0.9867) were not much different.
Conclusions: Over the years, vaginal birth after cesarean rate is decreased.
Keywords: Cesarean section; fetal distress; institutional delivery; obstetric care; uterine rupture