bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Report Infestasi Psitocobrossus sp pada Macaw (Ara macao)
Authors: Yesica Reza 
Published: November 2020

ABSTRAKMacaw termasuk jenis burung yang berukuran besar dan bersuara keras. Dengan nama latin Ara macao, burung ini mempunyai sifat yang lincah, cerdas, dan sangat ramah. Di dunia terdapat 18 spesies macaw, beberapa di antaranya termasuk spesies yang dilindungi. Ektoparasit merupakan salah satu parasit yang banyak ditemukan pada hewan peliharaan dan satwa liar. Salah satu ektoparasit yang sering menyerang burung adalah infestasi kutu. Kutu (lice) memakan bulu dan kulit. Spesies kutu eksklusif dalam kelompok burung beo adalah Psittacobrosus. Kutu ini termasuk dalam keluarga menoponidae. Dalam penelitian ini diambil sampel dari macaw betina berumur 3 tahun yang dibawa ke Rumah Sakit Hewan Pendidikan Universitas Brawijaya. Hasil pemeriksaan menunjukkan bahwa ektoparit yang diduga tergolong Psittacobrosus sp. Pengobatan yang digunakan pada kasus ini adalah dengan Carbaryl 5%, Tetraclorvinphos spray 0,5% serta menjaga kebersihan kandang.
The Impact of Islamic Economics and Finance Courses on Islamic Financial Literacy
Authors: Alfarisi Mohamad Fany , Agestayani A. , Delfiani Silvi 
Published: November 2020

<p class="Abstract">The present study seeks to investigate the impact of Islamic economics courses on Islamic financial literacy of university students. Additionally, it intends to compare Islamic financial literacy of those who have taken Islamic economics and finance courses and those who have not. With respect to the approach, the current study employed a quantitative approach to explain the linkage between the two variables. The population of the present study was all currently enrolled students of public universities in Padang particularly those from the faculty of economics and business. A self-administered questionnaire had been used to collect primary data. From the total distributed questionnaire, 300 of them were completed and included in the sample. As a result the respond rate is 71.3%. The results show 145 respondents are in the category of having poor Islamic financial knowledge, while 155 respondents are in the category of moderate From 145 respondents with poor Islamic financial knowledge 79 respondents (66%) have (not) taken (any) Islamic economics and finance courses. From 155 respondents with moderate financial knowledge 114 respondents (41%) have not taken any Islamic economics and finance courses. The findings of the present study suggest that most respondents can be categorized as having moderate knowledge and attending formal Islamic economics and finance courses can positively contribute to have a greater level of Islamic financial literacy.</p>
Incidence of Symptomatic Pediatric Tarsal Coalition in Olmsted County
Authors: Jackson Taylor J. , Larson A. Noelle , Mathew Smitha E. , Milbrandt Todd A. 
Published: November 2020

Background:
Tarsal coalitions are an important reason for foot pain in children. Early estimates placed the prevalence at up to 2%, while more recent data suggest that it is as high as 11% to 13%. To our knowledge, there have been no population-based studies to determine the true incidence of symptomatic tarsal coalitions in a pediatric population.

Methods:
A population-based database was used to identify all new diagnoses of symptomatic tarsal coalitions in children 18 years old or younger between 1966 and 2018. Patient records were reviewed for clinical data, and comparisons were made between the types and characteristics of the coalitions identified to determine differences in the affected populations. The annual age-specific, sex-specific, and type-specific incidence rates were estimated.

Results:
During the study period, 58 patients with a total of 79 symptomatic tarsal coalitions were identified (annual incidence = 3.5 per 100,000 children). There were 43 calcaneonavicular (CN) coalitions (annual incidence = 1.9 per 100,000 children), 27 talocalcaneal (TC) coalitions (annual incidence = 1.2 per 100,000 children), as well as 9 other coalitions (7 talonavicular, 1 naviculocuboid, and 1 naviculocuneiform) (annual incidence = 0.4 per 100,000 children). The overall incidence peaked between the ages of 10 and 14 years for both boys and girls (8.1 per 100,000 and 7.4 per 100,000 children, respectively). Statistical differences were identified between the types of tarsal coalitions. TC coalitions present at an older age relative to CN and other coalitions (mean,13.9, 12.7, and 11.4 years, respectively; p = 0.02). While CN and TC coalitions were similar in composition (23% and 30%, respectively, were osseous as opposed to fibrocartilaginous), other coalitions were more likely to be osseous (78%) (p = 0.0035). Other coalitions were also less likely to require surgery than CN and TC coalitions (11%, 74%, and 56%, respectively; p = 0.0015).

Conclusions:
This population-based study demonstrates differences in the clinical presentation of tarsal coalitions and provides an estimate of the true incidence of symptomatic tarsal coalitions in a pediatric population.
SOLVING THE PUZZLE OF THE BIVALVE SHELL FRAGMENT: INFERRING THE ORIGINAL ABUNDANCE AND SIZE FREQUENCY FROM THE FRAGMENTED RECORD
Authors: POWELL ERIC N. 
Published: November 2020

ABSTRACTMuch of the contribution of bivalves to paleoecology is based on the fraction preserved whole. The use of fragments has been limited by the inability to reconstruct the whole shell. For this study, shells of selected species were broken, metrics obtained for shell reconstruction, and a stepwise model developed and tested to evaluate the potential of reconstructing whole shells from fragments. The model is based on the facts that shell thickness is well correlated with shell length, width, and weight, that fragments can be assigned to shell areas, and that each shell area can be matched to a potential donor shell by combinations of length, width, and weight. Simulations using the model show that shell reconstructions are feasible and that the size frequency can be reconstructed more accurately than the number of shells. If all fragments are preserved, shell number tends to be modestly overestimated. Assuming fragment loss, the shell number estimated will be a conservative estimate of original abundance. Reconstructed size frequencies did not differ significantly from the original size frequencies of the whole shells even if 40% of the fragments were not preserved. Biovolume, consequently, may also be estimable. Standardly, bivalve fragments are enumerated by counting intact umbos. If all fragments are preserved, this approach is preferable, as shell model reconstructions overestimate abundance under that circumstance. However, the expectation that fragments with intact umbos are uniquely well preserved is unrealistic and if fragment loss has occurred, relying on all fragments may provide an improved estimate of the original abundance and, in addition, an estimate of the size frequency and the latter proves to be robust even with 40% of the fragments lost.
Modeling the Contribution of Individual Coal Seams on Commingled Gas Production
Authors: Santiago Vanessa , Ribeiro Ayrton , Hurter Suzanne 
Published: November 2020

SummaryIn coal-seam-gas (CSG) fields, where single wells tap multiple seams, it is likely that some of the individual seams hardly contribute to gas recovery. This study aims to examine the contribution of individual seams to the total gas and water production considering that each seam can have different properties and dimensions. A sensitivity analysis using reservoir simulation investigates the effects of individual seam properties on production profiles.A radial model simulates the production of a single CSG well consisting of a stack of two seams with a range of properties for permeability, thickness, seam extent, initial reservoir pressure, coal compressibility and porosity. The stress dependency of permeability obeys the Palmer and Mansoori (1998) model. A time coefficient (α) relates seam radius, viscosity, porosity, fracture compressibility, and permeability. It is used to aid interpretation of the sensitivity study. Finally, two hypothetical simulation scenarios with five seams of different thicknesses and depths obtained from producing wells are explored. The range in properties represents conditions found in the Walloon Coal Measures (WCM) of the Surat Basin, relevant to the Australian CSG industry.Each seam in the stack achieves its peak production rate at different times, and this can be estimated using α. Seams with lower α reach the peak gas rate earlier than those with higher α-coefficient. The distinct behavior of gas-production profiles depends on the combination of individual seam properties and multiseam interaction. At a αratio &gt; 1 (i.e., αtop/αbottom &gt; 1), the bottom seam peaks first but achieves lower gas recovery than the top seam. An increasing αratio is associated with the inhibition of less-permeable seams and reduced overall well productivity. For αratio &lt; 1, the top seam experiences fast depletion and total gas-production rates decrease drastically. This outcome is confirmed by a more realistic scenario with a higher number of coal layers. Poor combination of seams leads to severe production inhibition of some coal reservoirs and possible wellbore crossflow. The contrast of the seam-lateral extent in the stack and fracture compressibility play an important role in well productivity in the commingled operation of a stack of coal seams. Unfortunately, the lateral extent of individual coal seams is difficult to estimate and poorly known and, therefore, represents a major uncertainty in gas-production prognosis. The αratio analysis is a useful tool to gain understanding of modeled well productivity from commingled CSG reservoirs.
Evolution of comorbidities in people living with HIV between 2004 and 2014: Cross-sectional analyses from ANRS CO3 Aquitaine Cohort
Authors: Bonnet Fabrice , Marec Fabien Le , Leleux Olivier , Gerard Yann , Neau Didier , Lazaro Estibaliz , Duffau Pierre , Caubet Olivier , Vandenhende Marrie-Anne , Mercie Patrick , Cazanave Charles , Dabis Francois 
Published: November 2020

Abstract
Background:The objective of the study was to describe the evolution of chronic non-AIDS related diseases and their risk factors, in patients living with HIV (PLHIV) in the French ANRS CO3 Aquitaine prospective cohort, observed both in 2004 and in 2014 in order to improve long-term healthcare management.Methods:The ANRS CO3 Aquitaine cohort prospectively collects epidemiological, clinical, biological and therapeutic data on PLHIV in the French Aquitaine region. Two cross sectional analyses were performed in 2004 and 2014, to investigate the patient characteristics, HIV RNA, CD4 counts and prevalence of some common comorbidities and treatment.Results:2,138 PLHIV (71% male, median age 52.2 years in 2014) were identified for inclusion in the study, including participants who were registered in the cohort with at least one hospital visit recorded in both 2004 and 2014. Significant increases in the prevalence of diagnosed chronic kidney disease (CKD), bone fractures, cardiovascular events (CVE), hypertension, diabetes and dyslipidaemia, as well as an increase in treatment or prevention for these conditions (statins, clopidogrel, aspirin) were observed. It was also reflected in the increase in the proportion of patients in the “high” or “very high” risk groups of the disease risk scores for CKD, CVE and bone fracture score.Conclusions:Between 2004 and 2014, the aging PLHIV population identified in the French ANRS CO3 Aquitaine prospective cohort experienced an overall higher prevalence of non-HIV related comorbidities, including CKD and CVD. Long-term healthcare management and long-term health outcomes could be improved for PLHIV by: careful HIV management according to current recommendations with optimal selection of antiretrovirals, and early management of comorbidities through recommended lifestyle improvements and preventative measures.
Common social determinants for overweight and obesity, and dental caries among adolescents in Northern Norway: a cross-sectional study from the Tromsø Study Fit Futures cohort.
Authors: Stangvaltaite-Mouhat Lina , Furberg Anne-Sofie , Drachev Sergei N. , Trovik Tordis A. 
Published: November 2020

Abstract
Background. Non-communicable general and oral health conditions share common risk factors. Studies investigating common social determinants as risk factors for overweight/obesity and dental caries among the same adolescents are scarce and inconclusive. Methods. This cross-sectional study included data from 464 girls and 494 boys from the population-based Tromsø study Fit Futures, which included first-year students attending upper secondary school in 2010-2011 from two municipalities in Northern Norway (1038 participants in total, 93% participation rate). Multivariable binary logistic regression analyses stratified by sex were used to investigate the association between socioeconomic position indicators (adolescent’s own study program, parents’ education and employment status) and overweight/obesity indicated by body weight and waist circumference, untreated dental caries in dentine, and when these conditions were considered simultaneously.Results. Boys enrolled in the general studies and sports programs (versus vocational) had lower odds of being overweight/obese (POR 0.42, 95% CI 0.20-0.86 and POR 0.24, 95% CI 0.08-0.73, respectively), of having high waist circumference (POR 0.39, 95% CI 0.21-0.75 and POR 0.25, 95% CI 0.10-0.64, respectively), dental caries (POR 0.57, 95% CI 0.32-0.99 and POR 0.47, 95% CI 0.22-0.98, respectively), and being simultaneously overweight/obese, having high waist circumference and dental caries (POR 0.24, 95% CI 0.07-0.81 and POR 0.11, 95% CI 0.01-0.98, respectively). Girls enrolled in the general studies program (versus vocational) had lower odds of having dental caries (POR 0.50, 95% CI 0.30-0.84). Conclusions. Adolescent’s own study program was identified to be a common social determinant for overweight/obesity and dental caries among boys. These results support the broader concept of social determinants as common risk factors for general and oral health conditions, and call for common preventive strategies addressing these common social determinants among adolescents. However, there is a need for more studies to investigate and better understand the influence of social determinants on health conditions among adolescents.
Decrease in Membrane Fluidity and Traction Force Induced by Silica-Coated Magnetic Nanoparticles
Authors: Shin Tae Hwan , Ketebo Abdurazak Aman , Lee Da Yeon , Lee Seungah , Kang Seong Ho , Basith Shaherin , Manavalan Balachandran , Park Sungsu , Lee Gwang 
Published: November 2020

Abstract
Background Nanoparticles are being used increasingly due to their unique physical and chemical properties and small size. It is well-known that nanoparticles cause side effects, however their biophysical assessment remains challenging. We addressed this issue by investigating the effects of silica-coated magnetic nanoparticles containing rhodamine B isothiocyanate [MNPs@SiO2(RITC)] on the biophysical aspects, such as membrane fluidity and traction force of human embryonic kidney 293 (HEK293) cells. We further extended our understanding on the biophysical effects of nanoparticles on cells using a combination of metabolic profiling and transcriptomic network analysis. Results Overdose (1.0 μg/µl) treatment of MNPs@SiO2(RITC) induced lipid peroxidation and decreased membrane fluidity in HEK293 cells. During membrane damage, HEK293 cells were morphologically shrunk and aspect ratio of the cells were significantly decreased upon MNPs@SiO2(RITC) treatment. Each of traction force (measured in micropillar) was found to be increased, thereby increasing the total traction force in MNPs@SiO2(RITC)-treated HEK293 cells. Due to the reduction in membrane fluidity and elevation of traction force, velocity of the cell movement was significantly decreased in MNPs@SiO2(RITC)-treated HEK293 cells. Moreover, intracellular ATP also decreased in a dose dependent manner upon MNPs@SiO2(RITC) treatment. To understand the biophysical changes in cells, we analysed transcriptome and metabolic profiles and generated metabotranscriptomics network. The network showed relationships among peroxidation of lipid, focal adhesion, cell movement, and related genes and metabolites. Furthermore, in silico prediction of the network showed increment in the peroxidation of lipid and suppression of focal adhesion and cell movement.Conclusion Taken together, our results demonstrate that overdosage of MNPs@SiO2(RITC) impairs cellular movement, followed by changes in the biophysical properties of cells, thus highlighting the need for biophysical assessment of nanoparticle-induced side effects.
Conformer-Dependent VUV Photodynamics and Chiral Asymmetries in Pure Enantiomers of Gas Phase Proline
Authors: Hadidi Rim , Bozanic Dusan , Ganjitabar Hassan , Garcia Gustavo , Powis Ivan , Nahon Laurent 
Published: November 2020

Abstract
Proline is a unique amino-acid, with a secondary amine fixed within a pyrrolidine ring providing specific structural properties to proline-rich biopolymers. Gas-phase proline possesses four main H-bond stabilized conformers differing by the ring puckering and carboxylic acid orientation. The latter defines two classes of conformation, whose large ionization energy difference allows a unique conformer-class tagging via electron spectroscopy. Photoelectron circular dichroism (PECD) is an intense chiroptical effect sensitive to molecular structures, hence theorized to be highly conformation-dependent. Here, besides a conformer-dependant cation fragmentation behaviour, we present experimental evidence of an intense and striking conformer-specific PECD, measured in the VUV photoionization of proline. This finding, combined with theoretical modelling, allows a refinement of the conformational landscape and energetic ordering, that proves inaccessible to current molecular electronic structure calculations. Additionally, astrochemical implications regarding a possible link of PECD to the origin of life’s homochirality are considered in terms of plausible temperature constraints.
Characterization of Stable Hypoxia-Preconditioned Dental Pulp Stem Cells: Implication for Pulp Regeneration
Authors: Zayed Mohammed , Iohara Koichiro , Watanabe Hideto , Ishikawa Mami , Tominaga Michiyo , Nakashima Misako 
Published: November 2020

Abstract
Background: Dental pulp stem cells (DPSCs) have been developed as a potential source of mesenchymal stem cells (MSCs) for regeneration of dental pulp and other tissues. However, further strategies to isolate highly functional DPSCs beyond the colony-forming methods are required. Our clinical study has demonstrated safety and efficacy of DPSCs isolated by G-CSF-induced mobilization and cultured under normoxia (mobilized DPSCs, MDPSCs) for pulp regeneration. It is well known that the oxygen concentration is closely linked to the maintenance of stemness. Thus, in this investigation, hypoxia-preconditioned DPSCs (hpDPSCs) was characterized to develop and improve the clinical utility for regeneration of dental pulp in endodontics.Methods: Colony-forming DPSCs were isolated and preconditioned with hypoxia in a stable closed cultured system and compared with MDPSCs isolated from the individual dog teeth. We examined the proliferation rate, migration potential, anti-apoptotic activity and gene expression of the stem cell markers and angiogenic/neurotrophic factors. Trophic effects of the conditioned medium (CM) were also evaluated. In addition, the expression of immunomodulatory molecules upon stimulation with IFN-γ were investigated. The pulp regenerative potential and transplantation safety of hpDPSCs were further assessed in pulpectomized teeth in dogs by histological and immunohistochemical analyses and by chemistry of blood and urine. tests Results: hpDPSCs demonstrated higher proliferation rate and expression of a major regulator of oxygen homeostasis, HIF-1α, and a stem cell marker, CXCR-4. The direct migratory activity of hpDPSCs in response to G-CSF was significantly higher than MDPSCs. The CM of hpDPSCs stimulated neurite extension. However, there were no changes in angiogenic, migration and anti-apoptotic activities compared with the CM of MDPSCs. The expression of immunomodulatory gene, PTGE was significantly up-regulated by IFN gamma in hpDPSCs compared with MDPSCs. However, no difference in nitric oxide was observed. The regenerated pulp tissue was quantitatively and qualitatively similar in hpDPSC transplants compared with MDPSC transplants in dog teeth. There was no evidence of toxicity or adverse events of the hpDPSC transplantation Conclusions: These results demonstrated that hpDPSCs improved stem cell properties compared to MDPSCs, suggesting their potential clinical utility for pulp regeneration.
Dental Pulp Stem Cells: an Alternative Source of Mesenchymal Stem Cells with Potential Osteogenic Regenerative Capacities
Authors: Mucientes Arkaitz , Herranz Eva , Moro Enrique , González-Corchón Aranzazu , Peña-Soria María Jesús , Pena Pilar , Baudín Carmen , Abasolo Lydia , Rodriguez-Rodriguez Luis , Lamas José Ramón , Fernandez-Gutierrez Benjamin 
Published: November 2020

Abstract
Background: Bone innate ability to repair without scaring is surpassed by major bone damage. Current gold-standard strategies do not achieve a full recovery of the bone biomechanical properties. To bypass these limitations, tissue engineering techniques based on hybrid materials made up of osteoprogenitor cells, like mesenchymal stem cells (MSCs), and bioactive ceramic scaffolds, like calcium phosphate-based (CaPs), are promising. Biological properties of the MSCs, including osteogenic potential, are influenced by the tissue source. The aim of this study is to define the MSC source and construct (MSC and scaffold combination) most interesting for its clinical application in the context of bone regeneration.Methods: MSCs of 9 healthy donors were isolated from adipose tissue, bone marrow and dental pulp. MSCs were cultured both on plastic surface and on CaPs (hydroxyapatite and β-tricalcium phosphate) to compare their biological features: proliferation rate, osteogenic potential, cell viability and activity, ability to colonize the CaPs and ALP activity. Results: iTRAQ results generated the hypothesis that anatomical proximity to bone has a direct effect on MSC phenotype. On plastic, MSCs isolated from dental pulp (DPSCs) were the MSCs with the highest proliferation capacity and the greatest osteogenic potential. On both CaPs, DPSCs are the MSCs with the greatest capacity to colonize bioceramics. Furthermore, results show a trend for DPSCs are the MSCs with the most robust increase in the ALP activity.Conclusion: Based in our results, we propose DPSCs as a suitable MSCs for bone/dental regeneration cell-based strategies.