bluuebunny/crossref_metadata_2025_split huggingface dataset:
Double VEGF/HGF Gene Therapy in Critical Limb Ischemia Complicated by Diabetes Mellitus
Authors: Barć Piotr , Antkiewicz Maciej , Śliwa Barbara , Frączkowska Katarzyna , Guziński Maciej , Dawiskiba Tomasz , Małodobra-Mazur Małgorzata , Witkiewicz Wojciech , Kupczyńska Diana , Strzelec Bartłomiej , Janczak Dariusz , Skóra Jan Paweł 
Published: September 2020

AbstractCritical leg ischemia (CLI) complicated by diabetes mellitus (DM), which is a very common and dangerous disease, represents the ultimate stage of peripheral arterial disease. Patients are treated with antiplatelet drugs, statins and limb revascularization, but a significant number of patients are not candidate for revascularization. Literature shows that in such cases, gene therapy could be a perfect therapeutic option. The aim of our study was to evaluate efficacy of double vascular endothelial growth factor/hepatocyte growth factor (VEGF/HGF) gene therapy in patients with CLI complicated by DM. We observed that 90 days after administration, serum level of VEGF and ankle-brachial index increased significantly (p < 0.001) and rest pain decreased significantly compared with the control group (p < 0.002). Moreover considerable improvement in vascularization was observed in computed tomography angiography (P = 0.04). Based on the results of this study, we suggest that the therapy with pIRES/VEGF165/HGF bicistronic plasmid administration is a safe and effective method of treatment of patients with both CLI and DM.
Can a Cultural Variant Dedicated to Arab-Muslim Tourists Save the Tunisian Tourism Sector?
Authors: Abdmouleh Rim , Kalai Maha 
Published: September 2020

AbstractUnanimously recognised as a growing sector in today’s world, cultural tourism continues to attract the attention of researchers seeking to exhume the mechanisms and dynamics that govern it. In terms of political and strategic choices, Tunisia is currently giving this sector an increasingly remarkable interest. It is in this perspective that we tried to carry out a survey that would highlight the opinions of Arab-Muslim visitors about cultural tourism in Tunisia. To this end, we relied on the principal component analysis and the probit models that we considered the most appropriate to deal with our problem. Using individual data from a sample of 300 Arab-Muslim tourists who visited Tunisia during the summer vacation of 2014, we tried to interpret the results that seemed very suggestive. Our analysis of the different results led us to deduce that it is difficult for the Tunisian destination to motivate the Arab-Muslim visitors by focusing on the cultural tourism (in its current state) and that it is not the best way to attract this category of tourists. In the light of the obtained results, we have proposed some solutions that could promote this destination and fructify this type of alternative tourism.
Is the concept of “peanut-free schools” useful in the routine management of peanut-allergic children at risk of anaphylaxis?
Authors: Reese Imke , Ahrens Birgit , Ballmer-Weber Barbara , Beyer Kirsten , Blümchen Katharina , Doelle-Birke Sabine , Heratizadeh Annice , Kleine-Tebbe Jörg , Lange Lars , Lau Susanne , Lepp Ute , Mahler Vera , Schäfer Christiane , Schnadt Sabine , Szepfalusi Zsolt , Wassmann-Otto Anja , Werfel Thomas , Worm Margitta 
Published: September 2020

Summary
Background
Parents of school-age children with food allergies and potential anaphylactic reactions want their children to have an unburdened and risk-free everyday school life. Thus, particularly in the case of peanut allergy, demands for peanut-free schools are put forward.

Results and discussion
The position paper of the food allergy working group of the German Society for Allergology and Clinical Immunology (Deutsche Gesellschaft für Allergologie und klinische Immunologie) highlights why the concept of peanut-free schools does not protect peanut allergic children, but rather bears potential disadvantages and risks for all those involved. The focus on peanut as a potential trigger of anaphylactic reactions ignores other relevant triggers.

Conclusion
In order to address the fears and concerns of patients, parents, and school staff, it is mandatory to develop various coping strategies. These should enable and ensure the safety and participation of food-allergic pupils in classes and other school activities. Therefore, it is important to implement adequate measures for allergen avoidance and emergency treatment for students with confirmed food allergies.
The Diagonality Problem of EU Rule of Law and Human Rights: Proposal for an Incorporation à l’européenne
Authors: Nagy Csongor István 
Published: September 2020

AbstractThe EU’s limited powers do not enable its institutions to effectively intervene in cases where Member State actions threaten fundamental values. The recent controversies emerging from some Member States’ human rights and rule of law backsliding turned this question to one of the core issues of the European project, calling for effective fundamental rights protection in the EU without suppressing national constitutional identities. Though EU law’s approach, at least at first glance, might appear to be idiosyncratic, it is far from unprecedented and, as far as multilevel constitutionalism is concerned, EU law may draw on the experiences of various regimes where centralized human rights protection and national or state constitutional identities coexist. This Article analyzes the current European approach as to the application of the federal bill of rights to states from a comparative perspective and explores the constitutional and jurisprudential patterns addressing the question of inquiry in a multilevel constitutional architecture. The Article analyzes the subject from a doctrinal, ontological, textual-conceptual, and institutional perspective with the aim of contributing to the current European debate with a new comparative perspective and fostering EU constitutional development with structural patterns. It submits that the currently prevailing paradigm of “scope” should be replaced or complemented with the paradigm of “core standards” and proposes a doctrine of European incorporation, arguing that the diagonally applicable rule of law and human rights requirements should be incorporated via Article 2 TEU to make them judicially applicable.
A Revised Democratic Critique of EU (Citizenship) Law: From Relative Homogeneity to Political Judgment
Authors: Neuvonen Päivi Johanna 
Published: September 2020

AbstractThe mainstream democratic critique of EU law rejects the argument that standard EU citizenship rights have a democracy-enhancing effect within the EU Member States. This Article shows how the democratic critique can benefit from a critique of critique that is missing in the discussion on the democratic effects of EU law. From this perspective, the Article makes an original contribution to critical EU legal studies at three levels. First, the critique of essentialist binary oppositions revisits what is political in the interests protected under EU citizenship rights. Second, the Article demonstrates how an Arendtian theory of political judgment counteracts the mainstream democratic critique in assessing the effects of EU citizenship law on democratic politics. Finally, reopening the question of what the conditions for democracy are translates into a methodological argument that rejectionist critique must yield to a more developed critical methodology in EU legal studies.
The Conceptualization of Constitutional Supremacy: Global Discourse and Legal Tradition
Authors: Romeo Graziella 
Published: September 2020

AbstractThis Article argues that a) constitutional supremacy is affected by the legal tradition, which implies that it is a concept largely shaped by the legal context in which it is elaborated, and b) the common law version of constitutional supremacy determines a sort of cultural resistance to constitutional imperialism. In making its argument, this Article begins with the doctrine of sources of law with a view to unpack its operational logic within the common law and, therefore, to understand how the supremacy of constitutions is conceptualized. It then examines the embryonic conceptualization of constitutional supremacy in the British legal culture by addressing the “constitutional statutes.” It goes on to analyse how constitutional supremacy is safeguarded in jurisdictions that are affected by the British tradition and equipped with written constitutions, to show how constitutions concretely established themselves as supreme laws without neglecting the relevance of traditions pre-dating the constitutional texts. It then shows how the common law finds its way to be applied alongside or even instead of the constitution. Eventually, this Article offers some conclusions as to the implications of such a conceptualization of constitutional supremacy for comparative and global constitutional studies.
Gauging “Ultra-Vires”: The Good Parts
Authors: Schneider Karsten 
Published: September 2020

AbstractThe Federal Constitutional Court’s ultra-vires case law—especially its most recent iterations—has more than its fair share of bad parts. It went from non-existence to global prominence in an alarmingly short period of time. Fortunately, the doctrine contains some extraordinarily good parts. Within the case law, there are three beautiful, elegant, and highly expressive elements that are buried under a massive tower of good intentions and hard luck: First, the principle of distinction between the two concepts of responsibility and accountability, second, the ban on transferring blanket empowerments, and third, the idea of a “program of integration”
as a good medium for expressing vague ideas. In combination, these elements constitute a constitutional mechanism that does not play hell with European law, but truly complements any union based on multi-level cooperation. Focusing on the good parts—and avoiding some bad parts—might help prospective ultra-vires reviews to steer clear of wreaking havoc. The subset of good parts can serve to shift the constitutional case law towards reliability, readability, robustness, foreseeability, and, if nothing else, explicability.
The European Economic Constitution after the PSPP Judgment: Towards Integrative Liberalism?
Authors: Goldmann Matthias 
Published: September 2020

AbstractThis article argues that the PSPP judgment effectively buries the era of financial liberalism, which has dominated the European economic constitution for decades. It raises the curtain on a new political paradigm, which I call “integrative liberalism”. Whereas the financial crisis put financial liberalism under strain, the development since then has been contradictory, torn between state intervention and market liberalism, focused above all on buying time rather than finding a new constitutional equilibrium. Now, together with the measures adopted in response to COVID-19, the PSPP judgment paves the way for profound change. Integrative liberalism is characterized by an overall shift from the market to the state, mitigating the post-crisis insistence on austerity and conditionality. Contrary to the embedded liberalism of the post-war era, integrative liberalism operates in a corrective and reactive mode with a focus on goals and principles, lacking the emphasis on long-term planning. Like every political paradigm, integrative liberalism ushers in a new understanding of the law. It puts the emphasis on context instead of discipline, and it elevates the proportionality principle. If integrative liberalism is to succeed, however, the democratic legitimacy of the Eurosystem and its independence require serious reconsideration.
Parent and Teacher Attitudes Towards Inclusive Education in Nauru
Authors: Page Angela , Berman Jeanette , Serow Penelope 
Published: September 2020

AbstractIt is recognised that the attitudes of parents and teachers are important in supporting inclusive education in developing countries. This study involved the application of quantitative research through the administration of a survey to determine the attitudes of parents and teachers in the Republic of Nauru. The results have provided preliminary data regarding attitudes related to the emergence of inclusive education in Nauru. Parents were more positive concerning issues that relate directly to the educational benefits of their children over more general benefits of inclusion in education. At this stage, teachers report higher levels of positive attitude than parents. A more fine-grained level of analysis revealed that there is a wide range of attitudes to aspects of education for students with disabilities, and areas of expertise needed to support inclusive education. This research has provided an understanding of current parental and teacher attitudes and levels of existing teacher expertise towards inclusion that is able to inform future policy development in Nauru.
MARINE RESERVOIR AGE CORRECTION FOR THE ANDAMAN BASIN
Authors: Raj Harsh , Bhushan Ravi , Muruganantham M , Nambiar Romi , Dabhi Ankur J 
Published: September 2020

ABSTRACTMarine reservoir age is an important component for correction in radiocarbon (14C) dating of marine and coastal samples. 14C concentration in pre-bomb marine samples of known age are used to derive marine reservoir age of a region. Annually banded coral from Landfall island in the northern Andaman has been analyzed for its 14C concentration during the pre-bomb period 1948–1951. 14C age and reservoir effect (∆R) are reported for these pre-bomb coral samples from the northern Andaman region. The mean 14C age of 331 ± 61 yr BP was obtained for the period 1948–1951 with an average reservoir age correction of –138 ± 61 yr. This reservoir age correction is lowest reported from the northern Indian Ocean. ∆R value of the northern Andaman and the Bay of Bengal appears lower than that of southern Andaman. The ∆R values obtained using mollusk shells and coral from the Andaman region shows large variability. The lower reservoir age correction for the Landfall Island situated in the northern part of the Andaman archipelago, could result due to freshwater flux and reduced upwelling in the region.
J. R. SEELEY AND JAPAN'S PACIFIC EXPANSION
Authors: DUSINBERRE MARTIN 
Published: September 2020

ABSTRACTIn the late nineteenth century, as Japanese scholars, traders, and labourers began to cross the Pacific Ocean in ever greater numbers, Tokyo-based intellectuals started to think about the significance of the ocean for the upcoming century. One prominent articulation of this ‘Pacific age’ was the result of an intellectual dialogue between a young Japanese student, Inagaki Manjirō (1861–1908), and his Cambridge professor, John Robert Seeley (1834–95). Traditionally framed as a relationship of ‘influence’ from teacher to pupil, and thus from West to East, the emergence of the ‘Pacific age’ was in fact the result of a sophisticated modulation of ideas from Seeley'sThe expansion of England(1883) into the rapidly changing politics of early 1890s Japan. This article traces that modulation in Inagaki's published works between 1890, when he graduated from Cambridge, and 1895, when Japan defeated China in the First Sino-Japanese War. It argues that Seeley's analyses, in Inagaki's hands, gave a significant impetus to existing expansionist visions in Japan, and thus constitute one example of late nineteenth-century history being written in the discursive space between Europe and East Asia.
DEVELOPMENTALISM IN LATE QING CHINA, 1874–1911
Authors: CHAPPELL JONATHAN 
Published: September 2020

AbstractThis article explores the changing historical referents that Qing officials used in arguing for the extension of direct governance to the empire's frontier regions from the 1870s to the 1900s. In the 1870s, Shen Baozhen and Zuo Zongtang made the case for a change of governance on Taiwan and in Xinjiang respectively by reference to past Chinese frontier management. However, in the first decade of the twentieth century Cen Chunxuan and Yao Xiguang both referred to the European past, and specifically the history of European colonialism, to argue for reform of frontier policy in Mongolia. I argue that this shift was a result of both the empire's altered political circumstances and a growing belief in the inevitability of an evolutionary fate which awaited nomadic peoples, who were destined to be colonized. Yet this was not a case of Chinese thinkers simply adopting European ideas and perspectives wholesale. The adoption of European historical referents was entangled with Han Chinese perceptions of Mongolian populations which had been carefully cultivated by the Manchu Qing state.
Compositional turnover in ecto- and endoparasite assemblages of an African bat,Miniopterus natalensis(Chiroptera, Miniopteridae): effects of hierarchical scale and host sex
Authors: Krasnov Boris R. , Junker Kerstin , Wood Simon , Ueckermann Edward A. , Venter Gert J. , van der Mescht Luther , Heyne Heloise , Jacobs David S. 
Published: September 2020

AbstractWe studied the compositional turnover in infracommunities and component communities of ecto- and endoparasites infesting a bat,Miniopterus natalensis(Chiroptera, Miniopteridae), across seven sampling sites using the zeta diversity metric (measuring similarity between multiple communities) and calculating zeta decline and retention rate (both scales) and zeta decay (component communities). We asked whether the patterns of zeta diversity differ between (a) infracommunities and component communities; (b) ecto- and endoparasites and (c) subsets of communities infecting male and female bats. The pattern of compositional turnover differed between infracommunities and component communities in endoparasites only. The shape of zeta decline for infracommunities indicated that there were approximately equal probabilities of ecto- and endoparasitic species to occur on/in any bat individual within a site. The shape of zeta decline for component communities suggested the stochasticity of ectoparasite turnover, whereas the turnover of endoparasites was driven by niche-based processes. Compositional turnover in component communities of ectoparasites was more spatially dependent than that of endoparasites. Spatial independence of compositional turnover in endoparasites was due to subcommunities harboured by female bats. We conclude that the patterns of compositional turnover in infracommunities were similar in ecto- and endoparasites, whereas the patterns of turnover in component communities differed between these groups.
WIKI-PIANO: EXAMINING THE CROWD-SOURCED COMPOSITION OF A CONTINUOUSLY CHANGING INTERNET-BASED SCORE
Authors: Kanga Zubin 
Published: September 2020

ABSTRACTAlexander Schubert's WIKI-PIANO.NET is an internet-based score, commissioned by the author and performed by him on an international tour from 2018 to 2020. The website score contains modules of notation, text, images, video and sound that can be edited by any member of the public, similar to a Wikipedia page. This article explores the huge volume and variety of content added to the score over the first 20 months after the premiere, and the extreme compositional approaches and unusual patterns of internet behaviour displayed. Examining these contributions offers insights into the online culture of new music, including its approaches to humour, its creative competitiveness, its mastery of memes, and its sophisticated subversions of the relationship between composer, performer and audience.
DECENTRING AND DISMANTLING: A CRITICAL AND RADICAL APPROACH TO DIVERSITY IN TERTIARY MUSIC EDUCATION
Authors: Ward Joanna 
Published: September 2020

AbstractThis article is a response, informed by my own recent experience of tertiary education in the UK, as well as my work as a composer, performer, researcher and activist, to the collection of articles published in TEMPO 292 addressing issues of diversity in music-making and tertiary music education in Australia. Though interventions have been successful in achieving better gender representation across musical contexts in Australian higher education institutions, I bring into question the long-term legitimacy of such empirical or revisionist approaches. Drawing on a range of feminist, poststructural, queer, and decolonial thought, I explore how conventional approaches to tertiary music education – both in terms of pedagogical methods, as well as assumed or prioritised content – enforce hegemonic and exclusionary value systems, hierarchies, ontologies and epistemologies. I also problematise some of the ways in which neoliberal and capitalist frameworks have become embedded within tertiary music education and advocate a process of destabilising and decentring assumed parameters, outlining how a critical, political and radical approach to music education might look.
Latitudinal shift in the timing of flowering of tree species across tropical Africa: insights from field observations and herbarium collections
Authors: Ouédraogo Dakis-Yaoba , Hardy Olivier J. , Doucet Jean-Louis , Janssens Steven B. , Wieringa Jan J. , Stoffelen Piet , Angoboy Ilondea Bhely , Baya Fidèle , Beeckman Hans , Daïnou Kasso , Dubiez Emilien , Gourlet-Fleury Sylvie , Fayolle Adeline 
Published: September 2020

AbstractTemporal and spatial patterns in flowering phenology were assessed for eight tropical African tree species. Specifically, the frequency and seasonality of flowering at seven sites in central Africa were determined using field data, graphical analysis and circular statistics. Additionally, spatial variation in the timing of flowering across species range was investigated using herbarium data, analysing the relative influence of latitude, longitude and timing of the dry season with a Bayesian circular generalized linear model. Annual flowering was found for 20 out of the 25 populations studied. For 21 populations located at the north of the climatic hinge flowering was occurring during the dry season. The analysis of herbarium collections revealed a significant shift in the timing of flowering with latitude forE. suaveolens, and with the timing of the dry season forM. excelsa(and to a lesser extentL. alata), with the coexistence of two flowering peaks near the equator where the distribution of monthly rainfall is bimodal. For the other species, none of latitude, longitude or timing of the dry season had an effect on the timing of flowering. Our study highlights the need to identify the drivers of the flowering phenology of economically important African tree species.