bluuebunny/crossref_metadata_2025_split huggingface dataset:
Photodynamic therapy in oncology: Present and future
Authors: Korshunova O. V. , Plekhova N. G. 
Published: November 2020

There is progress in applying photodynamic therapy in cancer clinic during the last decade. The promising direction to develop this way of treatment is the use of photosensitizers with given characteristics. It is based on a local activation of a photosensitizer in a cancer tissue by using luminous radiation of an appropriate wave length to launch photochemical reaction following the atypical cells’ destruction. In spite of a successful experience of using photodynamic therapy in different areas of medicine, not all its opportunities are studied. There are general information in this literature survey about the use of photodynamic therapy and its perspectives in oncology.
Stomach cancer on the territory of the Far Eastern Federal District
Authors: Gordienko V. P. 
Published: November 2020

Objective: General indexes of the disease and death rate among the Far East region due to stomach cancer during the last decade (2008–2017).Methods: Disease and death rates, statistical reports of patients with oncology and official documents by public health authorities were analyzed.Results: there were 25,155 new registered cancer cases in Far East region in 2017. It’s 26.6% higher than 10 years ago. 128,776 patients (2.1% of the region population) were under outpatient observation. In the structure of primary morbidity stomach cancer takes the fourth place, and in overall death-rate it’s on the 2nd place, going after trachea, bronchial and lung tumor. The number of patients having I–II phase of stomach cancer had increased from 2008 to 2017, the disease rate among women significantly decreased. The percentage of actively defined cases has increased by several orders for ten years. However the index of accumulation of contingents of the diseased with stomach cancer has decreased. The rate of morphological confirmation of such diagnosis turned out to be lower than the average rate in Russia. The proportion of the diseased registered for 5 years or more has exceeded average numbers. The death rate was the highest during the 1st year of being diagnosed. It can be explained by a very high rate of neglecting.Conclusions: comparing the increasing number of cancer diseased in Far Eastern Region, the constant decrease of the disease and death rates were noticed at the beginning of the 21st century. This fact can’t be explained by an exact reason now.
Generation of secondary radiation on the surface of endoprostheses used for breast reconstruction during mastectomy, after radiation therapy
Authors: Gulian I. S. , Nikiforova N. O. , Kustov V. N. , Temchenko V. V. , Mandryko A. S. , Nevozhay V. I. , Pankratov I. V. , Matvienko N. A. , Rudyuk V. P. 
Published: November 2020

Objective: Experimental estimate of the secondary radiation on the surface of implants and expanders, used for breast reconstruction in case of mastectomy, after making radiation therapy.Methods: Special equipment was constructed by radiation study department. It consists of linear accelerator as a source of ionizing radiation and a gamma-ray spectrometer with the detector on the basis of ultrapure germanium. The objects of research were the implants and expanders of the different producers.Results: The maximum amount of the secondary photons on the implants and expanders was generated on the energy level lower than 700 KEV. The level of photons’ generation between 600–300 KEV was higher on the surface of the implants than on the surface of expander filled with saline.Conclusion: The photons of the secondary radiation with the energy level from 100 to 700 KEV are generated under the influence of ionizing radiation on the implants and tissue expander filled with saline. It can be one of the causes of capsular contractures development after mastectomy.
Rekonstruksi Tujuan Pendidikan Islam: Studi Komparasi Pemikiran Majid Irsan al-Kilani dan Ahmad Dahlan
Authors: Ramadhan Ossi Marga 
Published: November 2020

The process of education always goes through dynamic stages. It always adapts to the atmosphere of the students' conditions and current development. Therefore the reconstruction of Islamic education’s purpose is very important. Especially during the era of al-Kilani and Ahmad Dahlan, both of them met their respective concerns so that they thought to modify and to change Islamic education’s purpose. This article aims to find the standpoint of their version of Islamic education’s purpose. It was library research that referred to the sources of related literature and was processed using comparative descriptive analysis. The finding showed that there were similarities between them, such as first, the similarity in the setting of purpose formulation. Second, there were also similarities in the basic foundation for their educational purpose which are Al-Qur'an and Al-Hadith. However, there were a few differences from their standpoint such as in aspects of educational background and intellectual heritage.
AVALIAÇÃO DE FERIDAS CUTÂNEAS EM JUMENTOS TRATADAS COM POMADA À BASE DE EXTRATO DE AMEIXA-BRAVA A 10%
Authors: Souza Juliany Alves de , Bezerra Francisco Ermerson Ferreira , Gonçalves José Bruno Landim , Moura Maria Francicarla Nascimento , Ramos Luís Carlos Estrela , Felix Naianne Araújo , Beltrão Eduardo Santiago , Knupp Sheila Nogueira Ribeiro 
Published: November 2020

<p><span style="font-size: medium;">: Objetivou-se com este trabalho avaliar feridas cutâneas em jumentos tratadas com pomada à base de <em>Ximenia americana</em> (ameixa-brava) 10%. Foram utilizados sete asininos adultos, machos, da raça nordestina. Os mesmo animais foram submetidos a dois tipos de tratamentos distintos, o tratado e o controle, utilizando-se uma ferida em cada hemitórax. Foram avaliados parâmetros macroscópicos e medidas das áreas das feridas. Também foi calculado o percentual de contração das feridas. Durante a inspeção dos parâmetros macroscópicos, não foi observada diferença entre os grupos. Na avaliação do percentual de contração das feridas o grupo tratado mostrou uma discreta maior contração. A partir dos resultados obtidos conclui-se que a pomada à base de extrato de ameixa-brava a 10% não demonstrou capacidade de acelerar o processo cicatricial.</span></p>
DIABETES MELLITUS ASSOCIADO A NEOPLASIA MAMÁRIA E OUTROS FATORES EM CÃO – RELATO DE CASO
Authors: Oliveira Susana Pereira de , Araújo Sandy Beatriz Silva de , Landim Camila Pontes , Dias Diane Cristina de Araújo , Filho Ewerton De Medeiros 
Published: November 2020

<p>A diabetes mellitus é uma doença sistêmica causada pela falta relativa ou absoluta de insulina. Suas complicações crônicas são as principais causas da morbidade e mortalidade. O objetivo deste trabalho foi relatar um caso de diabetes mellitus em cadela com neoplasia mamária. Na anamnese, foi relatado polifagia, poliúria, polidipsia, perda de peso e cegueira. No exame físico, foi constatado nódulo mamário na região torácica cranial esquerda, o qual foi caracterizado como neoplasia benigna. Foram solicitados exames complementares para a confirmação do diagnóstico. O animal foi então diagnosticado com diabetes mellitus, havendo indícios de demais acometimentos e endocrinopatias possivelmente correlacionadas. Optou-se pela mastectomia unilateral esquerda e controle da diabetes por insulinoterapia e dieta com ração formulada para diabéticos.</p><p> </p><p> </p><p> </p><p><strong>Palavras-chave: </strong>endocrinopatias; complicações crônicas; doença sistêmica.</p>
Tl-concentration dependence of scintillation properties in Tl-doped CsBr single crystals
Authors: Takahashi Kentaro , Kimura Hiromi , Nakauchi Daisuke , Kato Takumi , Kawaguchi Noriaki , Yanagida Takayuki 
Published: November 2020

Abstract
Photoluminescence and scintillation properties of CsBr single crystals with various concentrations of Tl (0.1%, 0.2%, 0.3%, 0.5% and 1%) were examined. Under an excitation at 260–280 nm and X-ray excitation, all the samples exhibited emission peaking around 360 and 510 nm with the decay time constants of μs order. The former emission would be due to 3P1 → 1S0 transitions of Tl+ ion associated with tetragonal structures, and the latter one was due to off-center configurations of self-trapped excitons localized near Tl+ ions at trigonal structures. The pulse height analysis under 137Cs γ-ray (662 keV) irradiation indicated that the 0.3%Tl-doped sample possessed the highest scintillation output among the prepared samples. From the results under various γ-ray irradiation, we confirmed that the scintillation output showed a good proportional response against γ-ray energy up to 1274 keV.
Low-energy cross-sectional cathodoluminescence analysis of the depth distribution of point defects in Si-ion-implanted β-Ga2O3
Authors: Sugie Ryuichi , Uchida Tomoyuki , Hashimoto Ai , Akahori Seishi , Matsumura Koji , Tanii Yoshiharu 
Published: November 2020

Abstract
Low-energy cross-sectional cathodoluminescence (CL) with a beam energy of 1 keV was applied to Si-ion-implanted β-Ga2O3 (−201) wafers to investigate implantation damage and recovery. The semi-quantitative CL-intensity depth profiles were obtained by considering nonradiative recombination at the surface. We found that the CL intensity did not fully recover, even after annealing at 1273 K. Such insufficient recovery was prominent in the Si-diffusion region, suggesting that Si-dopant activation and Si diffusion are strongly correlated through interaction with point defects generated by implantation, such as Si interstitials and Ga vacancies.
Zbuntowane oko
Authors: Giżycki Marcin 
Published: November 2020

Oko fascynuje artystów, pisarzy i filmowców od dawna. Najczęściej jednak i w literaturze, i w kinie pojawia się w szokującym kontekście – jest wyłupiane, oślepiane itp. Autor zastanawia się nad tym fenomenem, ale skupia się na dwóch filmach, które nie epatują okrucieństwem: Filmie Samuela Becketta i Alana Schneidera z 1965 r. i Klatce Sidneya Petersona z 1947 r. Oba filmy trwają dwadzieścia kilka minut i są nieme, ale łączy je też to, że można je interpretować, jako opowieści o rozdwojeniu jaźni.
Une « famille cathédrale » normande à la fin du XII e siècle. La famille de Cierrey, l’évêque Garin et le chapitre cathédral d’Évreux
Authors: Combalbert Grégory 
Published: November 2020

L’article propose d’abord un examen et une identification des membres de la famille de Cierrey qui appartiennent au chapitre cathédral d’Évreux à la fin du xii e et au tout début du xiii e siècle, y compris de l’évêque Garin (1193-1201), dont la carrière et la parenté demeurent sources de questions. Il identifie notamment tous les archidiacres qui proviennent assurément de la famille ou qui lui sont apparentés ainsi que le moment auquel ceux-ci sont entrés en fonction, ce qui met en lumière la manière dont l’évêque Garin s’appuie sur sa famille pour contrôler le chapitre et le diocèse. Il décrypte précisément les relations de parenté qui existent entre les différents personnages appartenant à la famille, en tenant compte des contradictions des sources à ce sujet. Il pose enfin la question de l’identification de l’évêque Garin de Cierrey et d’un personnage habituellement nommé Garin de Cissey, connu comme chantre du chapitre d’Évreux, à partir de leur dénomination dans les sources, de leur carrière respective et de la relation de chacun d’eux avec le duc Richard Cœur de Lion et les proches de ce dernier.
La prédominance de la « voie de cour » dans les coutumiers normands du XIII e siècle
Authors: Martin Vincent 
Published: November 2020

Les coutumiers normands du Moyen Âge valorisent particulièrement la résolution des litiges par la « voie de cour », qui confie aux personnes en charge de la justice le soin de trancher les différends au terme d’un procès. Ce constat n’est pas nouveau : il transparaît en particulier dans certains travaux de Jean Yver. La présente étude revient sur la prédominance du traitement judiciaire des conflits dans les usages normands du xiii e siècle en scrutant les dispositions du Très ancien coutumier de Normandie et de la Summa de legibus Normannie in curia laicali . Cette démarche permet non seulement de confirmer en les synthétisant nombre d’analyses effectuées par les chercheurs durant les dernières décennies, mais également de les enrichir par des réflexions nouvelles, en particulier en mettant en valeur certains passages qui, dans les coutumiers précités, n’ont guère été utilisés concernant la problématique envisagée. Cet article permet également de compléter les travaux plus anciens en mettant davantage en perspective les solutions normandes avec celles mises en œuvre, à la même époque, dans le reste du royaume.
L’identité fantasmée : altérités, métissages et races au Japon
Authors: Clercq Lucien-Laurent 
Published: November 2020

Le Japon est souvent appréhendé comme un ensemble ethniquement et culturellement homogène. Pourtant, les récents débats concernant l’identité japonaise enflammant les réseaux sociaux de l’archipel ne manquent pas de remettre en cause cette assertion. En effet, l’émergence d’un nombre important de personnalités métisses, appelées hâfu en japonais, questionne les fondements de la japonité : que signifie et d’où vient ce terme problématique confinant à une « moitié de », incluant ou excluant de l’identité japonaise selon les circonstances ? Ce terme met en exergue les nombreux enjeux qui furent liés à la pureté raciale et au racisme d’État censés garantir les bases d’une nation saine au Japon comme aux États-Unis, dans un contexte de forte rivalité des impérialismes.
Chapitre 3. De-colonizar la Bio-ética y el Ambiente: una tarea prioritaria del Pensamiento Ambiental Sur, en tiempos de penuria
Authors: Noguera De Echeverri Ana Patricia 
Published: November 2020

Comprendre les relations profondes entre biologie (logique de la vie, langage de la vie), bioéthique (ethos de la vie) et environnement (fruit de la relation écosystème-culture, Angel Maya, A. 1996), depuis le Sud que nous incarnons, implique de décoloniser, déconstruire ces trois termes depuis la Pensée Environnementale Sud. Il s’agit de les désanthropiser et de les reconfigurer depuis la géo-pensée, c’est-à-dire la pensée qui naît de notre terre. Considérer de manière tellurique l’éthique implique de la sentir dans la terre, comme compréhension de la langue de nature et de la vie. De la vie humaine, certes, mais sans exclure les formes de vie autres. Au contraire, il s’agit de dénoncer la manière à travers laquelle la vie est exploitée, mise au service de la production industrielle. La Pensée Environnementale Sud connecte la bioéthique avec l’environnement pour montrer l’étroite relation esthético-complexe entre ces deux mots. Le terme Abya Yala rend compte de cette réalité. D’origine Cuna, ce mot signifie bien-vivre et renvoie à la façon d’habiter de l’humain non-occidentalisé. Il signifie aussi la Terre généreuse, fertile et en floraison, mots qui évoquent la manière à travers laquelle l’Habitat permet à l’habitant d’habiter poétiquement la Terre. Naissent ainsi de nouveaux épistèmes éthico-esthétiques : des manières de connaître-comprendre-recréer, désoccidentalisées, configurées à partir d’autres logiques, d’autres façons de sentir, et qui montrent le gouffre abyssal entre la pensée occidentale et la pensée Sud.
Chapitre 4. Agriculture et Société : estompement de la norme ?
Authors: de Paul de Barchifontaine Christian 
Published: November 2020

L’industrialisation a développé des activités ingénieuses à des fins de profit. Cela touche tous les secteurs y compris l’agriculture et le souci est de vérifier les interactions positives ou négatives qu’on les différentes activités économiques les unes sur les autres. Pour ce faire, il est urgent d’intégrer les sciences de la Vie, dont fait partie l’agriculture, à une réflexion beaucoup plus globale pour l’avenir de la société en prenant en compte la diversité culturelle, les disparités économiques et sociales mais d’abord et avant tout en y intégrant les « constantes vitales » sans lesquelles il risque de ne pas y avoir d’avenir du tout.
Spatialités sociales à Paris à la veille de la Révolution
Authors: Varet-Vitu Anne , Marraud Mathieu , Mermet Éric 
Published: November 2020

La spatialisation des groupes sociaux est réputée difficile dans les villes d’Ancien Régime. Or, par la mise en place d’un SIG et la mobilisation de plusieurs méthodes et d’opérateurs spatiaux, 22 000 adresses parisiennes pour l’année 1789 ont pu être relevées dans les sources et spatialisées sur la ville à la veille de la Révolution. Le géocodage offre ainsi une vision globale de la localisation d’une grande fraction des habitants et en dévoile les répartitions à partir d’analyses socio-démographiques. Grâce à divers traitements et cartes thématiques, de nombreuses représentations des implantations sociales et des structures globales de la ville sont révélées, questionnant d’autant les cultures et pratiques de l’espace alors en usage. Tandis que chaque profession et activité sont détaillées par zones de densité, c’est aussi une exploration des proximités et des éloignements entre elles qui devient possible, nécessitant d’analyser le sens que ces relations spatiales pouvaient avoir sous la période.
Evaluation of the prevention of mother-to-child transmission programme at a primary health care centre in South Africa
Authors: Akinsanya Olusegun Solomon , Wiseman-Firtell Jill , Akpomiemie Goodman , Adeniyi Oladele Vincent , Kaswa Ramprakash 
Published: November 2020

Aim: To evaluate the effectiveness of the prevention of mother-to-child transmission (PMTCT) of the HIV programme at Levai Mbatha Community Health Centre (CHC), Evaton, South Africa.

Methods: A retrospective analysis of HIV-infected mother–infant pairs was conducted between 1 August 2009 and 31 July 2010. The infants’ HIV status was determined using HIV-specific qualitative DNA polymerase chain reaction (PCR). Demographic characteristics, mode of mother to child transmission (MTCT), choice of infant feeding, mode of delivery and CD4 count were included.

Results: Of the 206 mothers, 10 infants had positive DNA PCR results at 6 weeks. The MTCT rate was 4.9%. The mean age of HIV-infected mothers was 28 years (SD 5.7, range 16–42 years). Overall, 74.2% (152) of HIV-positive mothers received dual therapy
and 28.8% (53) were on HAART alone. Mothers with CD4 count < 200cells/μl (OR = 0.09 [CI, 0.01–0.75]; p = 0.026) and lack of prophylaxis during labour (OR = 9.50 [CI, 1.59–56.66]; p = 0.013) were identified as significant risk factors associated with MTCT.

Conclusions: The PMTCT programme at Levai Mbatha CHC is effective in reducing the MTCT of HIV. Lack of ART prophylaxis and low CD4 count were the significant determinants of MTCT in the study.

(Full text of the research articles are available online at www.medpharm.tandfonline.com/ojfp)

S Afr Fam Pract 2017; DOI: 10.1080/20786190.2016.1254933
Degree gaps for multipliers and the dynamical André–Oort conjecture
Authors: Ingram Patrick 
Published: November 2020

AbstractWe demonstrate how recent work of Favre and Gauthier, together with a modification of a result of the author, shows that a family of polynomials with infinitely many post-critically finite specializations cannot have any periodic cycles with multiplier of very low degree, except those that vanish, generalizing results of Baker and DeMarco, and Favre and Gauthier.
LncRNA gas5 regulates granulosa cell apoptosis and viability following radiation by x-ray via sponging miR-205- 5p and Wnt/β-catenin signaling pathway in granulosa cell tumor of ovary
Authors: Li Yan , Ma Xing , Li Jun , He Saifei , Zhuang Juhua , Wang Guoyu , Ye Ying , Xia Wei 
Published: November 2020

Purpose: To investigate the role of lncRNA gas5 in ovarian granulosa cells exposed to x-ray in granulosa cell tumor of ovary (GCTO).
Methods: KGN cell line was exposed to X-ray to mimic the radiotherapy for GCSO patients in vitro, cell viability was checked by CCK8 assays. RNA expression of apoptosis-related genes was determined by quantitative reverse transcriptase-polymerase reaction (qRT-PCR) while Western Blot for biomarkers in wnt/β-catenin signaling. Differential expressions of lncRNA gas5 were examined after cells were exposed to a ray for 0,24,48hs. We over expressed gas5 and assessed resultant cell viability, apoptosis and signaling. The sponging between gas5 and miR-205-5p was verified by luciferase assay. CCK8, qRT-PCR and Western blot were applied to investigate the correlation between miR-205-5p, cell viability, and apoptosis after miR-205-5p augmentation. Similarly, interaction between gas5 and miR-205-5p was assessed after co-transfection of miR-205-5p mimics and oe-gas5. Finally, wnt inhibitor was used to study the role of signaling pathway in KGN cells.
Results: Exposure of KGN to x-ray reduced cell viability and increased apoptosis. Gas5showed reduced expression in the cells, while miR-205-5p expression increased. Gas5 upregulation protected the cells against apoptosis and contributed to cell viability and activation of wnt//β-catenin signaling. lncRNA gas5 targeted miR-205-5p and miR-205-5p mimics counteracted the functions of up-regulated lncRNA gas5, regulating Wnt/β-catenin signaling pathway. Inactivation of Wnt/β-catenin suppressed cell viability.
Conclusions: lncRNA gas5 regulates cell apoptosis and viability following cellular radiation, thus presenting a potential therapeutic target for the application radiotherapy in GCTO patients.
Keywords: Ovary, Proliferation, Apoptosis, lncRNA gas5, Radiotherapy, β-catenin signaling
Hubungan Dukungan Keluarga Dengan Kepatuhan Diet Pada Penderita Hipertensi Di Wilayah Kerja Puskesmas Pancur Kabupaten Lingga Tahun 2020
Authors: Sari Nilam , Agusthia Mira , Rachmawaty M Noer  
Published: November 2020

Keberhasilan pengobatan hipertensi adalah kepatuhan melaksanakan diet. Dukungan keluarga berpengaruh terhadap kepatuhan diet hipertensi. Dukungan keluarga meliputi dukungan informasi, finansial, dukungan emosional dan dukungan penilaian atau penghargaan. Tujuan Penelitian untuk mengetahui hubungan dukungan keluarga dengan kepatuhan diet penderita hipertensi di wilayah kerja Puskesmas Pancur Kabupaten Lingga Tahun”2019?”.”Penelitian menggunakan metode deskriptif korelasi pendekatan secara cross sectional, pemilihan sampel dengan tekhikpurposive sampling, jumlah sampel 55 responden. Hasil penelitian diuji dengan uji Spearman Rho dengan derajat kemaknaan α = 0,00, diperoleh hasil p=0,000 dimana (p≤0,05), dengan kekuatan (r=0,851) yaitu sangat kuat dan arah hubungan positif artinya koefisien korelasi adalah signifikan, berarti”ada Hubungan Dukungan Keluarga Dengan Kepatuhan Diet Pada Penderita Hipertensi Di Wilayah Kerja Puskesmas Pancur Kabupaten Lingga”Tahun 2019. Diharapkan agar perawat dapat memberikan bimbingan pelayanan kesehatan bagi pasien hipertensi untuk dapat menyadari pentingnya kepatuhan diet hipertensi dan membantu keluarga agar memberi dukungan keluarga untuk membantu pasien mengotrol diet hipertensi