bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the potential use of powdered activated carbon in the treatment of effluents from bleached kraft pulp mills
Authors: Del’Antonio Nelson Rubens Nascimento , Silva Cláudio Mudadu , de Oliveira Kátia Dionísio , Nascimento Bernardo Albuquerque , Fonseca do Amaral João Pedro 
Published: December 2024

Abstract
Pulp mill effluents contain organic compounds derived from wood processing that resist conventional biological treatment. Studies suggest that powdered activated carbon (PAC) can enhance the quality of these effluents. Two types of PAC, chemically activated (PAC1) and physically activated (PAC2), were characterized and applied in dosages of 1, 2, and 3 g/L to reduce chemical oxigen demand (COD) and color in kraft pulp mill effluent. In Phase 1, physicochemical tests identified the optimal PAC type, dosage, and maximum cycles for effective COD and color reduction. In Phase 2, biological aerobic sequencing batch reactors (SBR) were tested with the optimal PAC from Phase 1. Results indicated PAC1 could be reused for COD reduction for up to 8 cycles and PAC2 for up to 6 cycles. For color reduction, PAC1 was effective for up to 4 cycles, while PAC2 failed to reduce color. The type of activation used by PAC1 proved to be more effective in reducing both COD and color than PAC2. Adding PAC1 (3 g/L) to the SBR increased COD removal from 70.5 % to 75.5 % and color removal from 26.6 % to 43.8 %, also improving sludge settling.
The effect of nanocellulose to coated paper and recycled paper
Authors: Durmaz Ekrem , Ates Saim , Atik Celil 
Published: December 2024

Abstract
This study investigated the properties of paper coated with nanocelluloses and nanocellulose-enhanced recycled paper derived from diverse waste paper sources. The grammages and thicknesses of both coated and recycled paper increased proportionally with the number of coating layers and the concentration of added cellulose nanofibrils (CNF) and cellulose nanocrystals (CNC). While the tensile index and modulus of elasticity of coated paper decreased post-coating, these properties of recycled paper improved with higher CNF concentrations, with minimal changes observed with CNC. The burst strength of coated paper increased with additional coating layers, regardless of whether CNF or CNC was used. The tear index of coated paper surpassed that of the base paper, while the burst strength of recycled paper with CNF exceeded that of CNC. Recycled paper with added nanocellulose exhibited higher tear index values than control paper, with CNF addition notably enhancing tear index compared to CNC. The types of nanocellulose significantly influenced the optical and barrier properties of both coated and recycled paper. In conclusion, this study suggests that leveraging CNF and CNC can enhance the quality of low-grade and recycled paper, potentially opening new avenues for their applications.
Venezuela y Bolivia en la Construcción de una Nueva Educación Pública Desafíos pedagógicos para el Socialismo del Siglo XXI
Authors: Imen Pablo 
Published: December 2024

El presente artículo se propone recorrer, en el marco de América Latina y asumiendo la existencia de un nuevo mapa regional, aspectos político-educativos y pedagógicos de dos de los países que se han propuesto recrear el proyecto del Socialismo del Siglo XXI. Se hace foco en la orientación de las políticas públicas, algunos dispositivos y proposiciones desplegadas en Venezuela y Bolivia, haciendo particular énfasis en las definiciones discursivas emanadas de las nuevas Cartas Constitucionales, y de las políticas educativas implementadas por los gobiernos. La exploración de estos procesos complejos habilita nuevas preguntas sobre la continuidad de dichos procesos y de confrontar con cierta eficacia frente a las pervivencias — especialmente en educación — de las posiciones tecnocráticas sostenidas por los proyectos neoliberal-conservadores que encuentran aún fuerzas de soporte en ámbitos de la sociedad civil y en espacios estatales aún colonizados por la perspectiva de la derecha política y pedagógica. ABSTRACT This article proposes to discuss, in the context of Latin America and assuming the existence of a new regional map, political-educational and pedagogical aspects of two countries that have been proposing themselves to recreate the project of the socialism in the XXI Century. It focus the orientation of public policies, some devices and propositions deployed in Venezuela and Bolivia, with particular emphasis on discursive definitions originated from the new Charters, and from educational policies implemented by the governments. The exploration of these complex processes enables new questions about the continuity of these processes and to confront with some efficiency the survivals — especially in education — of the technocratic positions held by neoliberal-conservative projects that are still supported by areas of civil society and in state spaces still colonized by the right political spectrum and pedagogical perspectives.
Educação em Atos de Pesquisa
Authors: Medeiros Cristina Carta Cardoso de 
Published: December 2024

O presente texto objetiva apresentar alguns dos artigos do sociólogo francês Pierre Bourdieu publicados na Revista Actes de la Recherche en Sciences Sociales, em que o autor aborda o tema Educação, a fim de identificar seu quadro teórico de análise. A partir da indicação de tal referencial, pretende-se contribuir para a divulgação dos pressupostos teórico-metodológicos desenvolvidos nesses textos e para a discussão de suas possibilidades de apropriação e utilização na construção de conhecimento em Educação no campo educacional brasileiro. Palavras-chave: Pierre Bourdieu, conceitos, Actes de la Recherche en Sciences Sociales
Mais anos na escola, mais tempo diário na escola: qualidade no ensino fundamental?
Authors: Coelho Lígia Martha da Costa , Fernandes Claudia de Oliveira 
Published: December 2024

No Brasil, o desempenho dos alunos do Ensino Fundamental tem levado a alternativas de reversão dos fracos índices apresentados e, neste início de século, duas possibilidades têm sido apontadas: o aumento dos anos de escolaridade e a ampliação da jornada escolar. O estudo analisa essas duas possibilidades, problematizando o significado da expressão qualidade escolar, quando a elas relacionada, pautando-se em reflexões acerca do tempo escolar e o ensino fundamental de nove anos, focalizados em uma perspectiva sociopolítica. Em relação ao tempo, chegamos a um referencial que discute o tempo na escola e a implantação de políticas públicas nesse sentido. Já qualidade é conceito aprofundado em suas múltiplas possibilidades, tomando-se como referência a qualidade social. O ensino fundamental de nove anos é abordado a partir de sua implementação pelo MEC. Nas considerações, relacionamos as diversas manifestações de ampliação do tempo de escola/de escolaridade e o que denominamos qualidade social do trabalho pedagógico exercido nas escolas públicas brasileiras. Palavras-chave: Ensino fundamental de nove anos; jornada escolar ampliada; qualidade no ensino fundamental
Educação, meio ambiente e história: a formação de professores em tempos de crise
Authors: Barreto Marcos 
Published: December 2024

O presente artigo procura fundamentar uma experiência pedagógica desenvolvida com estudantes de um curso de pedagogia (UFF), tendo em vista a gravidade da crise socioambiental contemporânea. Partindo do pressuposto de que tal crise expressa a insustentabilidade dos atuais padrões de produção e consumo de bens materiais e simbólicos, temos procurado identificar e trabalhar com as representações sociais dos estudantes sobre as relações entre as sociedades humanas e a natureza, sobre as noções de meio ambiente, de sustentabilidade, de impactos e riscos socioambientais. Para dialogar com os limites e as possibilidades críticas das representações elaboradas pela(o)s estudantes, temos recorrido aos estudos identificados com o campo da História Ambiental, explorando suas contribuições para entendermos as raízes históricas da presente crise, considerando os ambientes naturais do passado, os modos humanos de produção, assim como os modos de pensamento. Palavras-chave: educação, meio ambiente, história.
Investigating factors influencing quality of life in thyroid eye disease: insight from machine learning approaches
Authors: Zhang Haiyang , Wu Shuo , Yang Lehan , Fan Chengjing , Chen Huifang , Wang Hui , Zhu Tianyi , Li Yinwei , Sun Jing , Song Xuefei , Zhou Huifang , Smith Terry J , Fan Xianqun 
Published: December 2024

AimsThyroid eye disease (TED) is an autoimmune orbital disorder that diminishes the quality of life (QOL) in affected individuals. Graves’ ophthalmopathy (GO)-QOL questionnaire effectively assesses TED’s effect on patients. This study aims to investigate the factors influencing visual functioning (QOL-VF) and physical appearance (QOL-AP) scores in Chinese TED patients using innovative data analysis methods.MethodsThis cross-sectional study included 211 TED patients whose initial visit to our clinic was from July 2022 to March 2023. Patients with previous ophthalmic surgery or concurrent severe diseases were excluded. GO-QOL questionnaires, detailed medical histories and clinical examinations were collected. The distribution of GO-QOL scores was analyzed, and linear regression and machine learning algorithms were utilized.ResultsThe median QOL-VF and QOL-AP scores were 64.29 and 62.5, respectively. Multivariate linear regression analysis revealed age (P = 0.013), ocular motility pain (P = 0.012), vertical strabismus (P < 0.001) and diplopia scores as significant predictors for QOL-VF. For QOL-AP, gender (P = 0.013) and clinical activity (P = 0.086) were significant. The XGBoost model demonstrated superior performance, with an R2 of 0.872 and a root mean square error of 11.083. Shapley additive explanations (SHAP) analysis highlighted the importance of vertical strabismus, diplopia score and age in influencing QOL-VF and age, clinical activity and sex in QOL-AP.ConclusionTED significantly affects patient QOL. The study highlights the efficacy of XGBoost and SHAP analyses in identifying key factors influencing the QOL in TED patients. Identifying effective interventions and considering specific demographic characteristics are essential to improving the QOL of patients with TED.
Area and severity of ischemia according to dynamic single-photon emission computed tomography and myocardial perfusion scintigraphy in patients with multivessel coronary artery disease: comparison with the results of coronary angiography
Authors: Mochula A. V. , Tsygikalo A. A. , Maltseva A. N. , Mochula O. V. , Shipulin V. V. , Zatolokin V. V. , Alisherev Yu. U. , Kunitsyn S. A. , Kozlov B. N. , Zavadovsky K. V. 
Published: December 2024

Aim. To study the relationship between the coronary atherosclerosis involvement area and ischemia severity in terms of the consistency of dynamic single-photon emission computed tomography (SPECT) and myocardial perfusion scintigraphy (MPS) data with coronary angiography in patients with multivessel coronary artery (CAD) disease.Material and methods. The study included 327 patients with suspected or confirmed coronary artery disease (CAD), who previously underwent dynamic SPECT, MPS and invasive or computed tomography coronary angiography. Based on the data on coronary artery (CA) involvement, patients were selected: 1) with multivessel CAD (n=171), 2) with single-vessel CAD (n=71) and 3) non-obstructive CAD (n=85). Based on the MPS data, the presence and impaired perfusion area at rest and during the stress test, as well as the degree of their discrepancy were assessed: summed stress score (SSS), summed rest score (SRS) and summed difference score (SDS). The values of myocardial blood flow (MF) and MF reserve (MFR) were assessed using dynamic myocardial SPECT.Results. Standard MPS indices did not differ between the groups with non-obstructive, single-vessel and multivessel CAD as follows: 2,0 (0,0; 4,0) vs 5,0 (2,0; 7,0) vs 5,0 (3,0; 9,0) — SSS; 0,0 (0,0; 1,0) vs 3,0 (0,0; 5,0) vs 2,0 (0,0; 4,0) — SRS; 2,0 (0,0; 3,0) vs 3,0 (1,0; 6,0) vs 2,0 (0,0; 5,0) — SDS, respectively. The transient ischemic dilation did not differ between the study groups.Dynamic SPECT revealed a decrease (p<0,01) in global stress MF and MFR in patients with multivessel CAD compared to groups with non-obstructive and isolated single-vessel atherosclerosis: 1,07 (0,69; 1,49) vs 1,46 (1,08; 1,88) vs 1,48 (0,93; 1,89); 1,64 (1,16; 2,33) vs 2,28 (1,52; 2,93) vs 2,36 (1,58; 3,07), respectively.Net Reclassification analysis showed that MFR allows for correct reclassification of a significant proportion of patients with CAD compared to MPS (NRI=0,31, p=0,001).Conclusion. Dynamic myocardial SPECT is an adequate tool for assessing the ischemia volume in patients with extensive coronary involvement, and global MFR can be considered as one of the selection criteria for myocardial revascularization. The results obtained in this study require further study.
Long-term prognosis of life of patients after primary and recurrent myocardial infarction: data from two Russian registries (LIS-3 and RIMIS)
Authors: Martsevich S. Yu. , Zagrebelny A. V. , Zolotareva N. P. , Ginzburg M. L. , Kuzmina I. M. , Afonina O. S. , Sichinava D. P. , Drapkina O. M. 
Published: December 2024

Aim. To compare the long-term survival of patients after primary and recurrent myocardial infarction (MI) in the LIS-3 and RIMIS registries.Material and methods. The retrospective RIMIS registry included patients with acute transmural MI admitted to the emergency cardiology department of one of the Moscow vascular centers in 2017. A total of 214 patients were included, of which 23 people died in hospital and 191 people were included in the prospective registry part. Long-term vital status was assessed on average 6 years after discharge from hospital and was determined in 178 patients. The response rate was 93,19%. The prospective registry LIS-3 included all patients admitted to the Lyubertsy Regional Hospital with a diagnosis of acute coronary syndrome, of which 78 patients were discharged after confirmed MI in the first 9 months of 2014, and 164 patients were discharged after confirmed MI in the first 9 months of 2018. A total of 242 patients were included. Long-term vital status was determined in 207 patients. The response rate 85,5%. The median follow-up was 872 days. Comparative analysis of patient cohorts from the RIMIS and LIS-3 registries did not reveal any significant differences in the main demographic, anamnestic, and clinical parameters. The frequency of percutaneous coronary intervention in the acute stage of MI was higher in the RIMIS registry than in the LIS-3 registry (96,9 and 62,3%, respectively).Results. During the follow-up period, 31,4% of patients died in the RIMIS registry, and 20,8% of patients in the LIS-3 registry. Kaplan-Meier curves did not reveal any significant differences in patient survival in both registries. At the same time, in both registries, the long-term survival of patients after recurrent MI was significantly worse than that of patients who had a primary MI.Conclusion. Patients who had an acute MI, despite modern treatment in the acute stage, have a high residual risk of death. This is especially true for patients who had a recurrent MI.
Uterine sarcoma: the possibility of modeling a rare tumor and providing its morphological description
Authors: Frantsiyants E. M. , Shikhlyarova A. I. , Neskubina I. V. , Kaplieva I. V. , Trepitaki L. K. , Bandovkina V. A. , Pogorelova Yu. A. , Surikova E. I. , Moiseenko T. I. , Cheryarina N. D. , Tolmakh E. R. , Vereskunova A. A. , Ishonina O. G. , Verenikina E. V. , Menshenina A. P. 
Published: December 2024

Purpose of the study. To create a model of uterine sarcoma in female white mongrel rats and provide description of its morphological features. Materials and methods. In the in vivo experiment, white mongrel female laboratory rats (n = 20) weighing 250 ± 25 g were used, and the M1 strain of rat sarcoma was used as an experimental tumor model. The studied groups of animals: Group 1 (n = 10) – administration of 0.5 ml of tumor suspension containing 2.5–3.5 × 106 cells using an intravenous catheter with an injection port 22G, 0.9 × 25 mm; group 2 (n = 10) – donors of tumor material with subcutaneous M1 grafting according to the standard method. Xylazine‑ zolethyl anesthesia was used during surgical interventions. The duration of the experiment was 21 days. After killing the animals, median longitudinal histological sections were made from the tumor node, 5–7 microns thick, stained with hematoxylin‑ eosin. Results. Unlike subcutaneous grafting of sarcoma M1, the tumor growing in the uterine horn was characterized by the presence in the abdominal cavity of many nodules and tumor dropouts on the mesentery, i. e. lymph nodes. According to the cellular composition, tumors formed from a suspension of M1 sarcoma cells injected into the right horn of the uterus were characterized by a polymorphocellular type of structure against the background of pronounced neoangiogenesis. Necrosis and hemorrhages were noted in certain sections of the preparations with a polyp‑like tumor form, which corresponds to destructive signs of rapid growth and development of uterine sarcoma. Conclusion. The possibility of modeling a relatively rare tumor by introducing a suspension of M1 sarcoma cells into the right uterine horn of female rats has been established. The nature of multinodular tumor growth with pronounced polymorphism of the cellular composition, areas of necrotization and hemorrhage demonstrates the adequacy of the uterine sarcoma model for the implementation of research tasks in clinical oncology.
Investigating the Impact of the Hospital Information System on the Performance of Management Units at Pasteur Hospital in Bam from the Perspective of Managers
Authors: Akbarian Bafghi Mohammad Javad , Shafa Shaghayegh , Baghdervazeh Saeideh , Khosravi Sajjad , Pourhamidi Rasheed 
Published: December 2024

Background: The Hospital Information System (HIS) is a comprehensive information management system in hospitals that plays a significant role in the quality of managers' decisions. Therefore, this study aimed to examine the impact of the HIS on the performance of management units at Pasteur Hospital in Bam from the managers' perspective in the year 2023.
Method: The present study was an applied, descriptive, and cross-sectional study conducted in 2023. The performance of management units was examined in three clinical, human resources, and financial indicators. The study population consisted of all the managers at Pasteur hospital in Bam at three levels: executive, middle, and top management, who were entered into the study through a census (38 individuals). Information was collected using a standardized questionnaire, and for data analysis, SPSS 27 software and appropriate descriptive and analytical statistical tests (independent t-test and ANOVA) were used.
Results: Participating managers were 76.30 % women and 23.70 % men. 73.70 % of them had a bachelor's degree and most of them were in the category of operational and middle managers. From the point of view of the managers of the HIS, the greatest impact on the indicators of the trend of treatment activities (28.60 ± 5.35), cost (50.00 ± 3.60), productivity and training (32.35 ± 12.81) and the least impact on the indicators of information exchange (25.50 ± 4.67), income (32.33 ± 0.57), salary and wages (10.50 ± 5.00). In this study, three components—clinical, financial, and human resources—were examined separately by gender, education level, and management levels. The results of the independent t-test indicated that there was a significant difference only in the clinical component based on gender (p = 0.04)
Conclusion: To enhance the effectiveness of the HIS on managers' performance, it is essential to first conduct a comprehensive needs assessment of all management units. This needs assessment should identify the essential tasks and specific needs of each unit, and based on that, the enhancement of the HIS should be aligned with these needs. Moreover, paying special attention to the dimensions and indicators that receive less impact from this system can help improve the overall performance of the system and enhance its effectiveness in all aspects.
Design and Development of Novel Herbal Suppository Formulation for Prostatitis Treatment
Authors: Golembiovska Olena , Dmytrenko Oleksandra , Galkin Alexander 
Published: December 2024

Background. Prostatitis is a common inflammatory condition of the prostate gland, often treated with antibiotics and anti-inflammatory drugs, which may have limited efficacy and side effects. Herbal therapies offer a promising alternative due to their natural anti-inflammatory properties.
Objective. This study aims to design, develop, and evaluate physicochemical, biopharmaceutical and microbiological properties of novel herbal suppository formulations for the treatment of prostatitis, optimizing their biopharmaceutical profiles.
Methods. Excipients were selected to form suppositories with herbal ingredients known for their anti-inflammatory effects, specifically lovage, saw palmetto, and calendula CO2 extracts. The formulations were assessed based on key quality parameters, including organoleptic characteristics, average mass, melting point, deformation time, disintegration time, microbiological purity, and pH, ensuring compliance with European Pharmacopoeia (Ph. Eur.) standards. Biopharmaceutical studies compared the release profiles of active compounds from different suppository bases.
Results. Suppositories based on Witepsol® H15 exhibited satisfactory organoleptic properties, appropriate melting points, and acceptable deformation and disintegration times. The pH levels were within the required range, and microbiological tests confirmed purity. Biopharmaceutical evaluations showed that Witepsol® H15 suppositories had the most appropriate release rates of active compounds compared to those made with other bases.
Conclusions. The novel herbal suppositories developed in this study show promise for managing prostatitis based on preliminary evaluations of their physicochemical, microbiological, and biopharmaceutical properties. Further clinical studies are required to confirm their efficacy and safety.