bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regime specific spillover across cryptocurrencies and the role of COVID-19
Authors: Shahzad Syed Jawad Hussain , Bouri Elie , Kang Sang Hoon , Saeed Tareq 
Published: January 2021

AbstractThe aim of this study is to examine the daily return spillover among 18 cryptocurrencies under low and high volatility regimes, while considering three pricing factors and the effect of the COVID-19 outbreak. To do so, we apply a Markov regime-switching (MS) vector autoregressive with exogenous variables (VARX) model to a daily dataset from 25-July-2016 to 1-April-2020. The results indicate various patterns of spillover in high and low volatility regimes, especially during the COVID-19 outbreak. The total spillover index varies with time and abruptly intensifies following the outbreak of COVID-19, especially in the high volatility regime. Notably, the network analysis reveals further evidence of much higher spillovers in the high volatility regime during the COVID-19 outbreak, which is consistent with the notion of contagion during stress periods.
Preliminary engagement of a patient advisory board of African American community members with type 2 diabetes in a peer-led medication adherence intervention
Authors: Shiyanbola Olayinka O. , Kaiser Betty L. , Thomas Gay R. , Tarfa Adati 
Published: January 2021

Abstract
Background
The Peers Supporting Health Literacy, Self-efficacy, Self-Advocacy, and Adherence (Peers LEAD) program is a culturally tailored educational-behavioral 8-week intervention that addressed psychosocial and sociocultural barriers to diabetes medication adherence in African Americans. A brief 3-week version of the Peers LEAD intervention used a community engagement approach to examine the feasibility and acceptability of the intervention amongst patient stakeholders.

Main body
African Americans who were adherent to their diabetes medicines were paired with those who were non-adherent to their medicines. Together, they participated in the group and phone-based medication adherence intervention. Input from this brief intervention was important for the design of the remainder weeks of the 8-week program. The intervention targeted negative beliefs about diabetes, use of diabetes medicines, and offering culturally tailored peer support to improve medication adherence in African Americans. To receive input in the development and implementation of the program, we worked with community advisors and a peer ambassador board of African Americans who were adherent to their diabetes medicines. The peer ambassador board and community advisors reviewed intervention materials to ensure they were understandable and appropriate for the community. As well, they provided feedback on the process for intervention delivery.

Conclusion
The active engagement of the peer ambassador board and community advisors led to a revised intervention process and materials for a medication adherence program for African Americans with type 2 diabetes.
In vivo optical endomicroscopy: two decades of translational research towards next generation diagnosis of eosinophilic esophagitis
Authors: Wartak Andreas , Garber John G. , Yuan Qian , Shreffler Wayne G. , Hesterberg Paul E. , Katz Aubrey J. , Osman Hany , Leung Hui Min , Gao Anna , Otuya David O. , Grant Catriona , Gardecki Joseph A. , Nishioka Norman , Tearney Guillermo J. , Apiou-Sbirlea Gabriela 
Published: January 2021

AbstractHistopathologic analysis of biopsy specimens obtained via white light endoscopy (WLE) is the gold standard for the diagnosis of several mucosal diseases in the upper gastrointestinal (GI) tract. However, this standard of care entails a series of critical shortcomings such as missing depth information, high costs, time inefficiency, low-resolution imaging in vivo, high sampling variability, missing intrinsic tissue-specific contrast, and anesthesia related risk. In the quest for a diagnostic technology to replace the current standard of care, in vivo optical endomicroscopy has emerged as a promising alternative. This paper tells the story of a cluster of optical microscopy-based modalities invented, further developed, or first-validated in the laboratory of Dr. Guillermo J. Tearney (Tearney Lab) at the Wellman Center for Photomedicine of Massachusetts General Hospital over the past two decades, that combined lead to a novel method for diagnosis of eosinophilic esophagitis (EoE). Rather than being a comprehensive literature review, this paper aims to describe the translational journey towards a disease specific diagnostic and research tool for this increasingly recognized yet poorly understood immune-mediated disorder of the esophagus.
Effects of soil water content and light intensity on the growth of Molinia japonica in montane wetlands in South Korea
Authors: Choi Yu Seong , Park Hyun Jun , Kim Jae Geun 
Published: January 2021

Abstract
Background
Montane wetlands are unique wetland ecosystems with distinct physicochemical characteristics, and Molinia japonica often makes dominant communities in montane wetlands in South Korea. In order to figure out the environmental characteristics of M. japonica habitats and the major factors for the growth of M. japonica, field surveys were conducted in five wetlands from September to October 2019. Also, soil was collected at every quadrats installed in surveyed wetlands to analyze the physicochemical features.

Results
The relative coverage of M. japonica was higher in low latitude wetlands than in high latitude. Redundancy analysis showed that soil water content had the strongest effect on the growth of M. japonica (F = 23.0, p < 0.001). Soil water content, loss on ignition, and relative light intensity showed a high correlation with the density (R = 0.568, 0.550, 0.547, respectively, p < 0.01) and the coverage of M. japonica (R = 0.495, 0.385, 0.514, respectively, p < 0.01). Soil water content, loss on ignition, and pH were highly correlated with each other.

Conclusions
Molinia japonica lives in acidic wetlands at high altitude in temperate zone of low latitude, with peat layer placed on the floor. Also, M. japonica prefers open spaces to secure enough light for photosynthesis. High shoot production of M. japonica resulted in adding new peat material in every year, and this layer enforces the environmental characteristics of M. japonica habitats. This study may provide insights for further understanding of the method how wetlands maintain acidic condition by itself in montane wetlands in temperate zone.
Transpedal approach for femoral-popliteal chronic total occlusions using the outback® elite re-entry device
Authors: Gorenchtein Mike , Rajper Naveed , Green Philip , Khullar Pankaj , Amoruso Daniel , Bulacan Christian Franz , Kwan Tak , Puma Joseph , Ratcliffe Justin 
Published: January 2021

Abstract
Background
Transpedal access is increasingly utilized for the treatment of peripheral artery disease (PAD). Femoral-popliteal artery chronic total occlusions (CTOs) are some of the most difficult lesion subsets that sometimes require the use of re-entry support devices during percutaneous intervention. Limited data is available on the use of re-entry devices when treating femoral-popliteal CTOs via transpedal access. The aim of this study was to demonstrate the feasibility of using the Outback® Elite re-entry device for the treatment of femoral-popliteal CTOs via the transpedal approach in an outpatient based lab setting.

Methods
Seventeen patients presented with femoral-popliteal CTOs in which treatment required the use of the Outback® Elite re-entry device. All procedures were performed in a single outpatient based lab. Patients were followed at 1 week and 1 month post-procedure, with lower extremity arterial duplex ultrasound assessment during the 1 month follow-up.

Results
The average patient age was 78 years-old, with 71% being males. Most patients presented with Rutherford class IV symptoms. Procedural success was achieved in all patients with no requirement to convert to femoral artery access in any of the cases. No immediate post-procedural complications nor at any time during follow-up were observed. Ultrasonography at 1 month follow-up showed patent intervention sites and access site vessels in all patients.

Conclusion
The use of the Outback® Elite re-entry device for the treatment of femoral-popliteal CTOs via transpedal access is a feasible option and may have potential benefits by avoiding risks associated with traditional femoral artery access.
Physiological response of sweet corn (Zea mays Ls.) grown under sandy soil to α-tocopherol treatments and different irrigation systems
Authors: Badr Elham Abd Elmoneim , Sadak Mervat Shamoon , Bakhoum Gehan Shaker , Khedr Howida Hassan Ahmed 
Published: January 2021

Abstract
Background
Antioxidants or vitamins are organic compounds that are needed in tiny quantities and have stimulatory role on growth and productivity of different plants. Two field experiments were conducted in two summer seasons to investigate the role of two irrigation systems (spraying and dripping) and α-tocopherol foliar treatment with different concentrations (0, 100 and 200 mg/L) on some growth indices and physiological aspects, yield and its components of sweet corn plants.

Results
The results show that dripping irrigation system was more effective than Sprinkler system on increasing the studied growth indices and biochemical attributes as well as yield quantity and quality. The results also show the enhancing effect of different α-tocopherol treatments on growth indices, and yield quantity and quality of the sweet corn varieties via enhancing photosynthetic pigments, indole acetic acid, phenolics, carbohydrates constituents, free amino acids and proline contents. Moreover, the interaction between the two irrigation systems and different concentrations α-tocopherol showed that, dripping irrigation with 200 mg/L α-tocopherol was the most effective treatment on increasing growth, yield and yield components of sweet corn plants.

Conclusion
It could be concluded that dripping irrigation system was more effective than Sprinkler system on increasing the studied growth indices and physiological aspects, yield and its constituents. Moreover, treatment of maize plant with α-tocopherol could improve the studied growth indices, physiological aspects and consequently yield.
A renewable energy forecasting and control approach to secured edge-level efficiency in a distributed micro-grid
Authors: Anaadumba Raphael , Liu Qi , Marah Bockarie Daniel , Nakoty Francis Mawuli , Liu Xiaodong , Zhang Yonghong 
Published: January 2021

AbstractEnergy forecasting using Renewable energy sources (RESs) is gradually gaining weight in the research field due to the benefits it presents to the modern-day environment. Not only does energy forecasting using renewable energy sources help mitigate the greenhouse effect, it also helps to conserve energy for future use. Over the years, several methods for energy forecasting have been proposed, all of which were more concerned with the accuracy of the prediction models with little or no considerations to the operating environment. This research, however, proposes the uses of Deep Neural Network (DNN) for energy forecasting on mobile devices at the edge of the network. This ensures low latency and communication overhead for all energy forecasting operations since they are carried out at the network periphery. Nevertheless, the cloud would be used as a support for the mobile devices by providing permanent storage for the locally generated data and a platform for offloading resource-intensive computations that exceed the capabilities of the local mobile devices as well as security for them. Electrical network topology was proposed which allows seamless incorporation of multiple RESs into the distributed renewable energy source (D-RES) network. Moreover, a novel grid control algorithm that uses the forecasting model to administer a well-coordinated and effective control for renewable energy sources (RESs) in the electrical network is designed. The electrical network was simulated with two RESs and a DNN model was used to create a forecasting model for the simulated network. The model was trained using a dataset from a solar power generation company in Belgium (elis) and was experimented with a different number of layers to determine the optimum architecture for performing the forecasting operations. The performance of each architecture was evaluated using the mean square error (MSE) and the r-square.
Routine pre-employment echocardiography assessment in young adults: cost and benefits
Authors: Gaafar Ahmed , Gaafar Asmaa 
Published: January 2021

Abstract
Background
Conventional echocardiography is a safe, available, and accurate tool for cardiac structural and functional evaluation, but it should not cancel clinical assessment and history tacking, and indeed both are complementary. A pre-employment assessment is important for employees and community safety and suitability for a specific work requirement.

Results
Aiming to assess the value of routine pre-employment echocardiography for the detection of cardiac abnormalities, we examined seven hundred ninety-five persons who were routinely referred to us for pre-employment conventional echocardiography. Only 9 persons had structural cardiac abnormalities (1.3%) and distributed as follows: two had bicuspid aortic valve with isolated aortic regurgitation, one of them had mild AR, and the other had moderate AR. Two cases had mitral valve prolapse, one of them had trivial MR, while the other had a flail anterior leaflet with severe MR. One patient had atrial septal defect 1.5 cm with mild pulmonary hypertension and right-sided chambers dilatation. One patient had dextrocardia (situs inversus totalis) without other cardiac problems. One had moderate pulmonary hypertension and modest right-sided chambers dilation. Two patients had left ventricular hypertrophy. Surprisingly, we did not detect rheumatic valvular heart disease. The money cost of echocardiography tests for those 795 persons was 198,750 Egyptian pounds (LE); their transportation cost was about 19.800LE. The total group time cost of the tests was 265 h, total time lost at the waiting room was 1590 h, total transportation time lose was 2385 h, so the total time cost was about 4000 h. Using psychological stress questionnaire, 33 participants (4.2%) had results suggestive of a low sense of psychological pressure due to echocardiography examination, 221 participants (27.8%) had results suggestive of a moderate feeling of stress, while 541 participants (68%) had results suggestive of a high sense of stress.

Conclusion
We recommend against routine echocardiography for cardiac assessment in pre-employment assessment and to do it only for persons with abnormal clinical or ECG findings.
Imaging features associated with survival outcomes among colorectal cancer patients with and without KRAS mutation
Authors: Promsorn Julaluck , Chadbunchachai Payia , Somsap Kulyada , Paonariang Krisada , Sa-ngaimwibool Prakasit , Apivatanasiri Chaiwat , Lahoud Rita Maria , Harisinghani Mukesh 
Published: January 2021

Abstract
Background
Mutations in Kirsten rat sarcoma proto-oncogene (KRAS) have been shown to be associated with advanced-stage colorectal cancer (CRC), negative disease outcomes, and poor response to treatment. The purpose of this study was to investigate which CT features are biomarkers for KRAS gene mutation and impact the survival outcomes of colorectal cancer patients.

Results
Of the 113 CRC patients included in the study, 46 had KRAS mutations (40.71%) and 67 had no mutations (59.29%). Regional lymph node necrosis was the only imaging feature significantly associated with KRAS mutation (P = 0.011). Higher T staging and liver, lung, and distant metastasis were prognostic factors for CRC (P = 0.014, P < 0.001, P = 0.022, P < 0.001, respectively). There were no significant differences in overall survival between patients with KRAS mutations and those without (P = 0.159). However, in patients with no KRAS mutation, those with CRC on the left side had a significantly higher rate of survival than those with CRC on the right (P = 0.005).

Conclusion
Regional lymph node necrosis may be an imaging biomarker of CRC with KRAS mutation, possibly indicating poor prognosis.
Optimal reactive power dispatch: a bibliometric analysis
Authors: Shanono Ibrahim Haruna , Muhammad Aisha , Abdullah Nor Rul Hasma , Daniyal Hamdan , Tiong Meng Chung 
Published: January 2021

AbstractOptimal reactive power dispatch (ORPD) plays a significant role in the control and smooth operation of the power system through the enhancement of the network’s reliability, security, and economic aspects. This paper presents a bibliometric and visual analysis of ORPD-related research articles extracted from the Web of Science (WoS) database from its inception to October 29, 2019. A total of 263 articles drawn from 166 journals, published between 1989 and 2019, were retrieved and analysed using Excel, HistCite, and VOSviewer visualisation software. The total number of citations for the 263 articles ranges from 0 to 297. The top three journals with the most significant number of ORPD publications were the International Journal of Electrical Power and Energy Systems, Applied Soft Computing, and two journals qualified for the third place, IEEE Transaction on Power Systems and IET Generation Transmission and Distribution. The most active researcher is Provas Kumar Roy, with nine (9) articles from Kalyani Government Engineering College. The most trending/cited researcher is Yi Jia Cao, with 129 Total Local Citation Scores from Hunan University, Changsha. In terms of contribution by countries, India, China, Iran, and the United States were the most significant contributors with 27.8%, 20.9%, 11.8%, and 8% of the total articles, respectively. The top 5 most frequently used substantive keywords to identify the trending topic and research direction were Particle Swarm Optimisation, Genetic Algorithm, Gravitational Search Algorithm, Linear Programming, Evolutional Algorithm, and Hybrid Algorithm. This study provides a detailed outline and reveals the future research directions for both experienced and novice ORPD researchers to identify research topics, questions, and collaboration partners.
Three-dimensional fatigue crack propagation analysis of welded steel beam based on global-local numerical model
Authors: Zong Liang , Shi Gang 
Published: January 2021

AbstractThe existing fatigue assessment approaches were mainly conducted on the component level. The interaction of local component damage and the global response cannot be well addressed. In this study, three-dimensional (3D) fatigue crack propagation analysis approach based on global-local numerical model was implemented, and examined to be accurate and effective through a series of systematic experimental data obtained by Fisher. Afterwards, the approach was introduced into a typical steel truss bridge for realizing more refined fatigue assessment from the global structural level. The fatigue performance of the longitudinal steel welded beam in the steel truss bridge was investigated based on global-local model and local model respectively. It was found that there is no difference in terms of the fatigue crack growth mechanism between the simulation between global-local model and local model due to that the stress level of the whole structure is relatively low. At last, the effect of heavy haul train operation on the fatigue performance of the steel truss bridge was analyzed. It was observed that the residual life of the longitudinal steel welded beam would have an obvious reduction when the axle load was increasing. The research work in this study presents a technical solution for the fatigue assessment of the global structure and can provide beneficial reference for relevant practical engineering projects.
Impact of Community-Based Clinical Breast Examinations in Botswana
Authors: Dykstra Michael , Malone Brighid , Lekuntwane Onica , Efstathiou Jason , Letsatsi Virginia , Elmore Shekinah , Castro Cesar , Tapela Neo , Dryden-Peterson Scott 
Published: January 2021

PURPOSEWe evaluated a clinical breast examination (CBE) screening program to determine the prevalence of breast abnormalities, number examined per cancer diagnosis, and clinical resources required for these diagnoses in a middle-income African setting.METHODSWe performed a retrospective review of a CBE screening program (2015-2018) by Journey of Hope Botswana, a Botswana-based nongovernmental organization (NGO). Symptomatic and asymptomatic women were invited to attend. Screening events were held in communities throughout rural and periurban Botswana, with CBEs performed by volunteer nurses. Individuals who screened positive were referred to a private tertiary facility and were followed by the NGO. Data were obtained from NGO records.RESULTSOf 6,120 screened women (50 men excluded), 452 (7.4%) presented with a symptom and 357 (5.83%) were referred for further evaluation; 257 ultrasounds, 100 fine-needle aspirations (FNAs), 58 mammograms, and 31 biopsies were performed. In total, 6,031 were exonerated from cancer, 78 were lost to follow-up (67 for ≤ 50 years and 11 for > 50 years), and 11 were diagnosed with cancer (five for 41-50 years and six for > 50 years, 10 presented with symptoms). Overall breast cancer prevalence was calculated to be 18/10,000 (95% CI, 8 to 29/10,000). The number of women examined per breast cancer diagnosis was 237 (95% CI, 126 to 1910) for women of age 41-50 years and 196 (95% CI, 109 to 977) for women of age > 50 years. Median time to diagnosis for all women was 17.5 [1 to 32.5] days. CBE-detected tumors were not different than tumors presenting through standard care.CONCLUSIONIn a previously unscreened population, yield from community-based CBE screening was high, particularly among symptomatic women, and required modest diagnostic resources. This strategy has potential to reduce breast cancer mortality.