bluuebunny/crossref_metadata_2025_split huggingface dataset:
Groundwater flow below construction pits and erosion of temporary horizontal layers of silicate grouting
Authors: Dekker Joris M. , Sweijen Thomas , Zech Alraune 
Published: October 2020

AbstractInjection of silicate grouting materials is widely used to create temporary horizontal layers for reducing inflow of groundwater at construction sites, in regions with shallow water tables. The erosion of a grouting layer was investigated by means of analytical solutions for groundwater flow and transport within a pit after construction finished. Erosion is assumed to occur by dissolution of the temporary injection layer and subsequent advective transport. Thereby, the hydraulic conductivity changes with time. This paper presents novel analytical solutions and approximate solutions for the major fluxes in the construction pit as a function of the domain settings, aquifer gradient and hydraulic conductivity. In addition, the mass flux and the dilution ratio of erosion-related components leaving the construction pit and entering the aquifer are quantified. Derived solutions are verified against numerical simulations. A sensitivity study shows the impact of domain settings on fluxes and dilution ratio. The results confirm that mass flux of grout components increases with ongoing erosion. Thus, its effect on groundwater quality increases with time after construction ceased.
An optimal monotone contention resolution scheme for bipartite matchings via a polyhedral viewpoint
Authors: Bruggmann Simon , Zenklusen Rico 
Published: October 2020

AbstractRelaxation and rounding approaches became a standard and extremely versatile tool for constrained submodular function maximization. One of the most common rounding techniques in this context are contention resolution schemes. Such schemes round a fractional point by first rounding each coordinate independently, and then dropping some elements to reach a feasible set. Also the second step, where elements are dropped, is typically randomized. This leads to an additional source of randomization within the procedure, which can complicate the analysis. We suggest a different, polyhedral viewpoint to design contention resolution schemes, which avoids to deal explicitly with the randomization in the second step. This is achieved by focusing on the marginals of a dropping procedure. Apart from avoiding one source of randomization, our viewpoint allows for employing polyhedral techniques. Both can significantly simplify the construction and analysis of contention resolution schemes. We show how, through our framework, one can obtain an optimal monotone contention resolution scheme for bipartite matchings, which has a balancedness of 0.4762. So far, only very few results are known about optimality of monotone contention resolution schemes. Our contention resolution scheme for the bipartite case also improves the lower bound on the correlation gap for bipartite matchings. Furthermore, we derive a monotone contention resolution scheme for matchings that significantly improves over the previously best one. More precisely, we obtain a balancedness of 0.4326, improving on a prior 0.1997-balanced scheme. At the same time, our scheme implies that the currently best lower bound on the correlation gap for matchings is not tight. Our results lead to improved approximation factors for various constrained submodular function maximization problems over a combination of matching constraints with further constraints.
Drag Distribution in Idealized Heterogeneous Urban Environments
Authors: Sützl Birgit S. , Rooney Gabriel G. , van Reeuwijk Maarten 
Published: October 2020

AbstractLarge-eddy simulations of nine idealized heterogeneous urban morphologies with identical building density and frontal area index are used to explore the impact of heterogeneity on urban airflow. The fractal-like urban morphologies were generated with a new open-source Urban Landscape Generator tool (doi:10.5281/zenodo.3747475). The vertical structure of mean flow and the dispersive vertical momentum transport within the roughness sublayer are shown to be strongly influenced by the building morphologies. The friction velocity and displacement height show high correlations with the maximum building height rather than the average height. Well-known roughness parametrizations of the logarithmic layer cannot adequately capture the large spread observed in the large-eddy simulation data. A generalized frontal area index $${\Lambda }_f$$

Λ
f

is introduced that characterizes the vertical distribution of the frontal area in the urban canopy. The vertically distributed stress profiles, which differ significantly per simulation, are shown to roughly collapse upon plotting them against $${\Lambda }_f$$

Λ
f

. The stress distribution representing urban drag can be fitted with a third degree polynomial. The results can be used for more detailed and robust representations of building effects in the development of urban canopy models.
Determinants of pain in advanced HCC patients recieving hepatic artery infusion chemotherapy
Authors: Wu Zhiqiang , Guo Wenbo , Chen Song , Zhuang Wenquan 
Published: October 2020

SummaryPurpose Hepatic arterial infusion chemotherapy (HAIC) is one of the options to treat unresectable hepatocellular carcinoma (HCC). The majority of HCC patients suffer great pain in the course of HAIC treatment. To improve the quality of life and the efficacy of HAIC treatment, the causes of pain, the choice of an analgesic regimen, and the relationship between pain and prognosis of HCC were analyzed. Methods A total of 376 HCC patients under HAIC in our hospital were recriuted between March 2017 and September 2019. Multivariate linear regression analysis (stepwise) was used to calculate the potential factors related to the severe pain in HCC patients under HAIC. Analgesics treatments were carried out based on the results of the visual analogue scale (VAS) score which was used to evaluate the pain. Results The mean value of the VAS score is 3.604, which indicates that the pain in most patients is mild and endurable. Intra-arterial lidocaine injection is an effective method in most patients (96%, 361 of 376), and the total score of VAS is reduced from 1355 to 195 following lidocaine injection. Multivariate analysis suggestes that oxaliplatin (OXA) preparation time, hepatic artery diameter and OXA manufacturers (R2 = 0.859) are influential factors for pain scores. Conclusion This study demonstrates an effective way to systematically assess and ease pain in HCC patients with HAIC treatment. OXA preparation time, hepatic artery diameter, and OXA manufacturers are the potential influencing factors for pain. This work presented here will provide a detailed understanding of the clinical application of HAIC in advanced HCC patients.
Comparative judgement, proof summaries and proof comprehension
Authors: Davies Ben , Alcock Lara , Jones Ian 
Published: October 2020

AbstractProof is central to mathematics and has drawn substantial attention from the mathematics education community. Yet, valid and reliable measures of proof comprehension remain rare. In this article, we present a study investigating proof comprehension via students’ summaries of a given proof. These summaries were evaluated by expert judges making pairwise comparisons, which were used to generate a score for each summary. This approach, known as comparative judgement, has been demonstrated to generate reliable and valid scores when assessing other mathematical constructs. Our findings suggest that comparative judgement can produce valid and reliable assessments of the quality of student-produced proof summaries. We also explored which features of students’ proof summaries were most valued by the expert judges, and found that high-scoring summaries referenced a proof’s logical structure and the mechanism by which it reached a contradiction.
Barth syndrome cardiomyopathy: targeting the mitochondria with elamipretide
Authors: Sabbah Hani N. 
Published: October 2020

AbstractBarth syndrome (BTHS) is a rare, X-linked recessive, infantile-onset debilitating disorder characterized by early-onset cardiomyopathy, skeletal muscle myopathy, growth delay, and neutropenia, with a worldwide incidence of 1/300,000–400,000 live births. The high mortality rate throughout infancy in BTHS patients is related primarily to progressive cardiomyopathy and a weakened immune system. BTHS is caused by defects in the TAZ gene that encodes tafazzin, a transacylase responsible for the remodeling and maturation of the mitochondrial phospholipid cardiolipin (CL), which is critical to normal mitochondrial structure and function (i.e., ATP generation). A deficiency in tafazzin results in up to a 95% reduction in levels of structurally mature CL. Because the heart is the most metabolically active organ in the body, with the highest mitochondrial content of any tissue, mitochondrial dysfunction plays a key role in the development of heart failure in patients with BTHS. Changes in mitochondrial oxidative phosphorylation reduce the ability of mitochondria to meet the ATP demands of the human heart as well as skeletal muscle, namely ATP synthesis does not match the rate of ATP consumption. The presence of several cardiomyopathic phenotypes have been described in BTHS, including dilated cardiomyopathy, left ventricular noncompaction, either alone or in conjunction with other cardiomyopathic phenotypes, endocardial fibroelastosis, hypertrophic cardiomyopathy, and an apical form of hypertrophic cardiomyopathy, among others, all of which can be directly attributed to the lack of CL synthesis, remodeling, and maturation with subsequent mitochondrial dysfunction. Several mechanisms by which these cardiomyopathic phenotypes exist have been proposed, thereby identifying potential targets for treatment. Dysfunction of the sarcoplasmic reticulum Ca2+-ATPase pump and inflammation potentially triggered by circulating mitochondrial components have been identified. Currently, treatment modalities are aimed at addressing symptomatology of HF in BTHS, but do not address the underlying pathology. One novel therapeutic approach includes elamipretide, which crosses the mitochondrial outer membrane to localize to the inner membrane where it associates with cardiolipin to enhance ATP synthesis in several organs, including the heart. Encouraging clinical results of the use of elamipretide in treating patients with BTHS support the potential use of this drug for management of this rare disease.
Theoretical study of the phase transitions and electronic structure of (Zr0.5, Mg0.5)N and (Hf0.5, Mg0.5)N
Authors: Gharavi M. A. , Armiento R. , Alling B. , Eklund P. 
Published: October 2020

AbstractRock-salt scandium nitride has gained interest due to its thermoelectric properties including a relatively high Seebeck coefficient. This motivates research for other semiconductor materials that exhibit similar electronic structure features as ScN. Using density functional theory calculations, we have studied disordered solid solutions of (Zr0.5, Mg0.5)N and (Hf0.5, Mg0.5)N using the special quasi-random structure model. The results show that within a mean-field approximation for the configurational entropy, the order–disorder phase transformation between the monoclinic LiUN2 prototype structure and the rock-salt cubic random alloy of these mentioned solid solutions occur at 740 K and 1005 K for (Zr0.5, Mg0.5)N and (Hf0.5, Mg0.5)N, respectively. The density-of-states for the two ternary compounds is also calculated and predicts semiconducting behavior with band gaps of 0.75 eV for (Zr0.5, Mg0.5)N and 0.92 eV for (Hf0.5, Mg0.5)N. The thermoelectric properties of both compounds are also predicted. We find that in the range of a moderate change in the Fermi level, a high Seebeck coefficient value at room temperature can be achieved.
Structural Characterization of Two Polymorphs of 1-(4-Methylpyridin-2-yl)thiourea and Two Derived 2-Aminothiazoles
Authors: Böck Denise , Beuchel Andreas , Goddard Richard , Imming Peter , Seidel Rüdiger W. 
Published: October 2020

Abstract
Two polymorphic forms of 1-(4-methylpyridin-2-yl)thiourea (1) and the crystal and molecular structures of the 2-aminothiazoles N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (2) and N-(4-methylpyridin-2-yl)-4-(pyrazin-2-yl)thiazol-2-amine (3), derived from 1 and the respective α-bromoketone via the Hantzsch reaction, are described. Both polymorphic forms 1α (space group P21/c, Z = 4) and 1β (space group P21/n, Z = 8) crystallize in the monoclinic system but exhibit distinctly different intermolecular hydrogen bonding patterns. Compound 2 (orthorhombic, space group Pca21, Z = 8) forms polymeric N–H⋯N hydrogen-bonded zigzag tapes in the polar crystal structure, with a significant twisting between the thiazole and pyridine rings. In contrast, the crystal structure of 3 (monoclinic, space group P21/c, Z = 4) features nearly planar centrosymmetric N–H⋯N hydrogen-bonded dimers, which are laterally joined through long C–H⋯N contacts, affording a π⋯π stacked layered structure.

Graphic Abstract
Two polymorphs of 1-(4-methylpyridin-2-yl)thiourea and the crystal and molecular structures of two 2-aminothiazoles, derived from 1-(4-methylpyridin-2-yl)thiourea and α-bromoketones via Hantzsch reaction, are reported.
Modeling the Depositional Environment of the Sandstone Reservoir in the Middle Miocene Sidri Member, Badri Field, Gulf of Suez Basin, Egypt: Integration of Gamma-Ray Log Patterns and Petrographic Characteristics of Lithology
Authors: Radwan Ahmed E. 
Published: October 2020

AbstractUnderstanding the depositional setting of siliciclastics reservoir is fundamental process to exploration and development of hydrocarbon reservoirs and to the multi-phase cycle of the oil and gas industry. Typically, core samples from existing or potential reservoirs can be used for interpretation of depositional environment. However, the lack of core samples in certain reservoirs represents a challenge for reservoir development plans and further exploration. To overcome the absence of core samples in the middle Miocene Sidri Member in the Badri field, Gulf of Suez, this study aimed to reconstruct its depositional settings by coupling well logging patterns and petrographic characterization of ditch cuttings. Consequently, 30 thin section samples representing the reservoir section of four wells were described in detail and standard petrographic characteristics were determined. Then, gamma-ray (GR) log patterns of the studied reservoir wells were used for interpretation of depositional environment. Petrographic analysis indicates that the sandstone reservoir is fine- to medium-grained arkose with dominant siliceous cement and composed mainly of quartz, feldspars, and lithic fragments. Pores reflecting primary and secondary porosity as well as inter-granular pores are dominant. The facies analysis indicates that the studied member has a heterogeneous nature and rapid facies change; its main lithofacies are blocky sandstones, intercalated sandstones and shales, and shales. Three electrofacies were interpreted in the studied section: (1) electrofacies-A (blocky sandstones), which is characterized by a cylindrical-shaped (right boxcar) GR trend; (2) electrofacies-B (intercalated sandstones and shales), which is characterized by an irregular log trend with serrated shape; and (3) electrofacies-C (shales), which is characterized by irregular GR trend and has no character. The interpreted results indicate a tidal channel depositional setting for electrofacies-A, mixed tidal flat depositional setting for electrofacies-B, and low relief offshore mudstone depositional setting for electrofacies-C. Finally, the results illustrate how the coupling of GR patterns with the analysis of petrographic characteristics can be used to understand the depositional setting of a hydrocarbon reservoir that lacks core samples. This work could be useful for assessment of reservoir distribution and quality, for reduction of uncertainty during field development, as well as for providing useful insight to similar hydrocarbon reservoirs elsewhere.
Interpreting, analysing and modelling COVID-19 mortality data
Authors: Sornette Didier , Mearns Euan , Schatz Michael , Wu Ke , Darcet Didier 
Published: October 2020

AbstractWe present results on the mortality statistics of the COVID-19 epidemic in a number of countries. Our data analysis suggests classifying countries in five groups, (1) Western countries, (2) East Block, (3) developed Southeast Asian countries, (4) Northern Hemisphere developing countries and (5) Southern Hemisphere countries. Comparing the number of deaths per million inhabitants, a pattern emerges in which the Western countries exhibit the largest mortality rate. Furthermore, comparing the running cumulative death tolls as the same level of outbreak progress in different countries reveals several subgroups within the Western countries and further emphasises the difference between the five groups. Analysing the relationship between deaths per million and life expectancy in different countries, taken as a proxy of the preponderance of elderly people in the population, a main reason behind the relatively more severe COVID-19 epidemic in the Western countries is found to be their larger population of elderly people, with exceptions such as Norway and Japan, for which other factors seem to dominate. Our comparison between countries at the same level of outbreak progress allows us to identify and quantify a measure of efficiency of the level of stringency of confinement measures. We find that increasing the stringency from 20 to 60 decreases the death count by about 50 lives per million in a time window of 20 days. Finally, we perform logistic equation analyses of deaths as a means of tracking the dynamics of outbreaks in the “first wave” and estimating the associated ultimate mortality, using four different models to identify model error and robustness of results. This quantitative analysis allows us to assess the outbreak progress in different countries, differentiating between those that are at a quite advanced stage and close to the end of the epidemic from those that are still in the middle of it. This raises many questions in terms of organisation, preparedness, governance structure and so on.
Challenges of Implementing a Performance and Reward System in Higher Education Institutions in Pakistan: Perceptions of Top Leaders in Contending Regulatory Bodies
Authors: Khan Tayyeb Ali , Christensen Tom 
Published: October 2020

AbstractThis article is a study of the challenges of implementing a performance and rewards management system for academics (Tenure Track System - TTS) in Pakistan over the last decade. The main empirical focus is on the perceptions of the leading implementer, the Higher Education Commission (HEC). These are supplemented by the perceptions of the Provincial Higher Education Commission (PHEC) in Punjab. Semi-structured interviews and document analysis were the two methods used to collect data. The study is based on two perspectives from organizational theory, a structural and a cultural perspective. The main findings highlight how leaders implemented TTS despite its incompatibility with the structure and culture of public universities in Pakistan. The study also revealed tensions between two reward systems – BPS and TTS – as well as the effects of the 18th constitutional amendment on the implementation of higher education programs. This study contributes insights into the reform of the higher education system in developing countries in the context of NPM.
Analyzing temporal patterns of topic diversity using graph clustering
Authors: Hashimoto Takako , Shepard David Lawrence , Kuboyama Tetsuji , Shin Kilho , Kobayashi Ryota , Uno Takeaki 
Published: October 2020

AbstractDuring a disaster, social media can be both a source of help and of danger: Social media has a potential to diffuse rumors, and officials involved in disaster mitigation must react quickly to the spread of rumor on social media. In this paper, we investigate how topic diversity (i.e., homogeneity of opinions in a topic) depends on the truthfulness of a topic (whether it is a rumor or a non-rumor) and how the topic diversity changes in time after a disaster. To do so, we develop a method for quantifying the topic diversity of the tweet data based on text content. The proposed method is based on clustering a tweet graph using Data polishing that automatically determines the number of subtopics. We perform a case study of tweets posted after the East Japan Great Earthquake on March 11, 2011. We find that rumor topics exhibit more homogeneity of opinions in a topic during diffusion than non-rumor topics. Furthermore, we evaluate the performance of our method and demonstrate its improvement on the runtime for data processing over existing methods.
Historical Trends in Children Living in Multigenerational Households in the United States: 1870–2018
Authors: Pilkauskas Natasha V. , Amorim Mariana , Dunifon Rachel E. 
Published: October 2020

AbstractOver the last two decades, the share of U.S. children under age 18 who live in a multigenerational household (with a grandparent and parent) has increased dramatically. Yet we do not know whether this increase is a recent phenomenon or a return to earlier levels of coresidence. Using data from the decennial census from 1870 to 2010 and the 2018 American Community Survey, we examine historical trends in children’s multigenerational living arrangements, differences by race/ethnicity and education, and factors that explain the observed trends. We find that in 2018, 10% of U.S. children lived in a multigenerational household, a return to levels last observed in 1950. The current increase in multigenerational households began in 1980, when only 5% of children lived in such a household. Few differences in the prevalence of multigenerational coresidence by race/ethnicity or education existed in the early part of the twentieth century; racial/ethnic and education differences in coresidence are a more recent phenomena. Decomposition analyses do little to explain the decline in coresidence between 1940 and 1980, suggesting that unmeasured factors explain the decrease. Declines in marriage and in the share of White children most strongly explained the increase in multigenerational coresidence between 1980 and 2018. For White children with highly educated parents, factors explaining the increase in coresidence differ from other groups. Our findings suggest that the links between race/ethnicity and socioeconomic status and multigenerational coresidence have changed over time, and today the link between parental education and coresidence varies within racial/ethnic groups.
Does RE still matter?
Authors: Orchard Janet 
Published: October 2020

AbstractThe role which subject Religious Education (RE) plays in promoting religious literacy matters in my view, acknowledging that I am biased in my judgement, as my professional raison d’etre, thus livelihood, rests on it continuing. However, others similarly are biased, whether from a specific moral and religious or ideological perspective or their academic positioning. Given whether subject RE exists in schools, or not, is a normative affair. I re-visit an established philosophical discussion of possible justifiable aims for compulsory RE in schools considering these reasons in turn, with particular reference to the RE curriculum in England and South Africa. Resisting the urge to identify one over-riding aim for RE, for reasons I explain, I suggest all three of these potentially justifiable reasons can be seen to inter-relate and reflect on whether they might be re-considered more broadly and used to strengthen more recent theoretical work concerned with studying religion in inter-disciplinary ways which promote religious and related ‘literacies’? On the understanding of RE I seek to develop, the implications for teacher education and continuing professional development would be significant but worthwhile, I conclude, if RE is to be promoted as an entitlement which is taught well and adequately resourced to contribute to the flourishing of many children and young people.