bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of a dorsal closing wedge calcaneal osteotomy versus a posterosuperior prominence resection for the treatment of Haglund syndrome
Authors: Ge Zilu , Ma Lin , Tang Hong , Yang Mingyu , Yang Aining , Yuan Chengsong , Tao Xu , Zhou Binghua , Tang Kanglai , Chen Wan 
Published: January 2020

Abstract
Background Haglund syndrome is a common disease that causes posterior heel pain. The objective of this study was to compare the clinical outcomes between the dorsal closing wedge calcaneal osteotomy (DCWCO) and the posterosuperior prominence resection (PPR) for the treatment of this disease. Methods The retrospective study included 12 patients who received DCWCO and 32 who patients received PPR from January 2010 to August 2016. The patients were evaluated in terms of the American Orthopedic Foot Ankle Society ankle-hindfoot scale (AOFAS), the Victorian Institute of Sport Assessment Scale for Achilles tendinopathy (VISA-A), the Fowler-Philip angle, Bohler’s angle, and the calcaneal pitch angle, both pre- and postoperatively (at 3 months, 6 months, 1 year, and the latest follow-up). Results Both groups showed a significance increase in their AOFAS and VISA-A scores after the operation. The DCWCO group showed a lower AOFAS score than the PPR group after 6 months (77.6 ± 5.1 vs. 82.8 ± 7.8, P =0.037), but received higher scores in the latest follow-up (98.2 ± 2.3, vs. 93.4 ± 6.1, P =0.030). For the VISA-A scores, the DCWCO group had lower scores for 3 months (56.9 ± 13.9, vs. 65.2 ± 11.0, P =0.044), but showed higher scores in the latest follow-up (98.2 ± 2.6, vs. 94.3 ± 5.0, P =0.010) when compared with the PPR group. Both groups had a significant change in the Fowler-Philip angle and Bohler’s angle after the operation. The postoperative Fowler-Philip angle in the DCWCO group was greater than that of the PPR group (35.9° ± 4.9°, vs. 31.4° ± 6.2°, P =0.026). However, there was no statistical difference in any other angle between the two groups, postoperatively. Conclusions The DCWCO group had poorer short-term clinical outcomes but better long-term function and symptom remission, as compared with the PPR group, in the treatment of Haglund syndrome.
Role of parathyroid hormone and vitamin D supplementation in stroke among patients on peritoneal dialysis
Authors: You Xiaohan , Zhou Ying , Zhang Jianna , Zhou Qiongxiu , Shi Yanling , Su Zhen , Chen Chaoshen , Shao Rongrong , Zhang Ji 
Published: January 2020

Abstract
Background Continuous ambulatory peritoneal dialysis (CAPD) patients have a high incidence of stroke and commonly have increased parathyroid hormone levels and vitamin D insufficiency. We seek to investigate the incidence of stroke and the role of parathyroid hormone and vitamin D supplementation in stroke risk among CAPD patients.Methods This is a retrospective study enrolled a Chinese cohort of 980 CAPD patients who were routinely followed up in our department. The demographic and clinical data recorded at the time of initial CAPD and during follow-up time are collected. The included cases were separated into nonstroke and stroke groups. The role of parathyroid hormone and vitamin D supplementation for stroke in CAPD patients is evaluated. The primary endpoint is defined as the first-time occurrence of stroke, and composite endpoint events are defined as death or switch to hemodialysis during follow-up.Results A total of 757 eligible CAPD patients with a mean follow-up time of 54.7 (standard deviation (SD) 33) months were included in the study. The median incidence of stroke among our CAPD patients was 18.9 (IQR, 15.7 - 22.1) per 1000 person-years. A significant nonlinear correlation between baseline iPTH and hazard of stroke (p value of linear association = 0.2 and nonlinear association = 0.002) was observed in our univariate Cox regression analysis, and low baseline iPTH levels (≤150 pg/ml) were associated with an increased cumulative hazard of stroke. Multivariate Cox regression analysis indicated a significant interaction effect between age and iPTH after adjusting for other confounders. Vitamin D supplementation during follow-up was a predictive factor for stroke in our cohort.Conclusions CAPD patients suffered a high risk of stroke. Lower iPTH levels were significantly associated with an increased risk of stroke. Vitamin D supplementation is an independent predictive factor for stroke among CAPD patients.
The prevalence and immunological features of anti-glomerular basement membrane antibody in patients with HIV/AIDS
Authors: Wang Wenjing , Jia Xiao-yu Jia , Cui Zhao , Chen Yan , Wang Wei , Lou Jin-li , Zhao Ming-hui , Ying Sun 
Published: January 2020

Abstract
Background Anti-glomerular basement membrane disease (GBM) is an autoimmune disease caused by the deposition of circulating anti-GBM antibodies. The main target antigens are the non-collagen region of the α3(IV)NC1(α3 chain of type IV collagen). EA and EB are two classical antigen epitopes on α3. It has been reported that anti-glomerular basement membrane (GBM) antibodies could be detected in HIV/AIDS patients, but its immunological characteristics are still unclear. In this study, the immunological characteristics of the target antigens were clarified.Methods Total 93 HIV/AIDS patients and 20 healthy volunteers were selected in Beijing Youan Hospital from 2017 to 2018. Recombinant humanα1-α5(IV)NC1, chimeric protein E A , E B were used as solid phase antigens. Enzyme-linked immunosorbent assay was employed to measure concentrations and subtypes of serum IgG autoantibodies specially against GBM.Results Five out of the 93 patients with HIV/AIDS had low to moderate levels of anti-GBM antibodies. However, these patients presented with no clinical manifestation of any kidney injury or pulmonary hemorrhages. Compared with HIV/AIDS patients with negative antibodies, there were no significant differences in gender, age, CD4 + T cell count and HIV viral load. All five patients recognized non-collagenous domain1 (NC1) of alpha 3 chain of type IV collagen [(α3(IV)NC1] as classic anti-GBM patients, followed by α5(IV)NC1. The antibodies against α3(IV)NC1 was IgG3 predominant, but did not react with either of the classic epitopes on α3 (E A and E B ).Conclusion These data suggest a distinct immunological profile of anti-GBM antibodies in patients with HIV/AIDS, and might explain the non-pathogenic features of HIV/AIDS associated anti-GBM antibodies.
Effect of sugammadex versus glycopyrrolate–neostigmine mixture on catheter-related bladder discomfort after retrograde intrarenal surgery: A retrospective observational analysis
Authors: Koh Gi-Ho , Park Jun-Young , Yu Jihion , Seo Jin-Young , Lee Sang-A , Go YoonJu , Hwang Jai-Hyun , Seo Hyungseok , Kim Young-Kug 
Published: January 2020

Abstract
Background: Catheter-related bladder discomfort (CRBD) is one of the most common postoperative symptoms. Although sugammadex and glycopyrrolate–neostigmine mixture are both used for the reversal of neuromuscular blockade, their effects on CRBD have not been compared side-to-side. We investigated the effect of the neuromuscular blockade reversal agents on CRBD after urologic surgery. Methods: We retrospectively reviewed the medical records of 136 patients who underwent retrograde intrarenal surgery between July 2018 and January 2019. Patients were divided into the S group (sugammadex; n = 65) and the G group (glycopyrrolate–neostigmine mixture; n = 71). Primary outcome was moderate-to-severe CRBD at 0 h postoperatively. We also evaluated moderate-to-severe CRBD at 1, 2, and 6 h postoperatively, duration of postanesthetic care unit (PACU) stay, postoperative pain, postoperative analgesic requirement, and drug-related side effects. Results: The incidence of moderate-to-severe CRBD at 0 h postoperatively was significantly lower in the G group than in the S group (39.4% vs. 69.2%, p = 0.001). The two groups did not show significant differences in the incidences of moderate-to-severe CRBD at 1, 2, and 6 h postoperatively, postoperative pain, and postoperative analgesic requirement. The duration of PACU stay was significantly shorter in the G group (46.0 min vs. 53.0 min, p = 0.047). Except for dry mouth, drug-related side effects did not show significant differences between the two groups. Conclusion: Compared with sugammadex, glycopyrrolate–neostigmine mixture was associated with a lower incidence of CRBD immediately after urologic surgery and shorter PACU stay.
Low uptake of continuous subcutaneous insulin infusion therapy in people with type 1 diabetes in Ireland: a retrospective cross-sectional study.
Authors: Gajewska Katarzyna Anna , Bennett Kathleen , Biesma Regien , Sree Seamus 
Published: January 2020

Abstract
Background: The uptake of continuous subcutaneous insulin infusion (CSII) therapy in those with type 1 diabetes varies internationally and is mainly determined by the national healthcare reimbursement systems. The aim of this study is to estimate national and regional uptake of CSII therapy in children, adolescents and adults with type 1 diabetes in Ireland. Methods: A retrospective cross-sectional study was conducted utilizing the national pharmacy claims database in 2016. Individuals using CSII were identified by dispensing of infusion sets. The uptake of CSII was calculated as the percentage of people with type 1 diabetes claiming CSII sets in 2016, both in children and adolescent (age <18 years) and adult populations (≥18 years). Descriptive statistics including percentages with 95% confidence intervals (CIs) are presented, stratified by age-groups and geographical regions, and chi-square tests used for comparisons. Results: Of 20,081 people with type 1 diabetes, 2,111 (10.5%, 95%CI: 10.1%-10.9%) were using CSII in 2016. Uptake was five-fold higher in children and adolescents at 34.7% (95%CI: 32.9%-36.5%) than in adults at 6.8% (95%CI: 6.4%-7.2%). Significant geographical heterogeneity in CSII uptake was found, from 12.6% to 53.7% in children and adolescents (p<0.001), and 2% to 9.6% in adults (p<0.001). Conclusions: Uptake of CSII in people with type 1 diabetes is low in Ireland, particularly in those ≥18 years. Identification of barriers to uptake, particularly in this group, is required.
Employment of PSO algorithm to improve the neural network technique for radial distribution system state estimation
Authors: Hussein Husham Idan , Salman Ghassan Abdullah , Ghadban Ahmed Majeed 
Published: January 2020

Abstract
This study presented a new hybrid algorithm to improve the state estimation (SE) of radial distribution power systems (PSs). The proposed particle swarm optimization–neural network (PSO–NN) algorithm constructed an independent and fast monitoring system with high accuracy that can detect abnormal conditions or failures in a PS. In this study, PSO was adopted to determine the appropriate weights of the NN model. The speed and accuracy of PSO with the NN model were evaluated in the SE of power system networks (PSNs). The information obtained through SE was used to enhance the operations and customer service delivery in terms of energy consumption and power quality in PSNs. Capacitor banks were installed to reduce the losses and improve the voltage profiles. The PSO–NN algorithm was assessed on IEEE (9, 33, and 69) bus standards. Simulation results proved that the new technique can be tested on any distribution network because of its accurate and efficient SE. Results indicated that the PSO–NN algorithm had better performance than the phasor measurement units.
Implementing a lightweight Schmidt-Samoa cryptosystem (SSC) for sensory communications
Authors: Al-Haija Qasem Abu , Marouf Ibrahim , Asad Mohammad M. , Nasr Kamal Al 
Published: January 2020

Abstract
One of the remarkable issues that face wireless sensor networks (WSNs) nowadays is security. WSNs should provide a way to transfer data securely particularly when employed for mission-critical purposes. In this paper, we propose an enhanced architecture and implementation for 128-bit Schmidt-Samoa cryptosystem (SSC) to secure the data communication for wireless sensor networks (WSN) against external attacks. The proposed SSC cryptosystem has been efficiently implemented and verified using FPGA modules by exploiting the maximum allowable parallelism of the SSC internal operations. To verify the proposed SSC implementation, we have synthesized our VHDL coding using Quartus II CAD tool targeting the Altera Cyclone IV FPGA EP4CGX22CF19C7 device. Hence, the synthesizer results reveal that the proposed cryptographic FPGA processor recorded an attractive result in terms of critical path delay, hardware utilization, maximum operational frequency FPGA thermal power dissipation for low-power applications such as the wireless sensor networks.
Assessment of Cau River water quality assessment using a combination of water quality and pollution indices
Authors: Son Cao Truong , Giang Nguyen Thị Huong , Thao Trieu Phuong , Nui Nguyen Hai , Lam Nguyen Thanh , Cong Vo Huu 
Published: January 2020

Abstract
This research aims at using a combined water quality index (WQI) and pollution index (PI) to assess and characterize river water quality of Cau River which is one of the longest rivers in the north of Vietnam. Five different water quality and water pollution indices were used including the Water Quality Index (WQI), Comprehensive Pollution Index (CPI), Organic Pollution Index (OPI), Eutrophication Index (EI), and Trace Metal Pollution Index (TPI). The combined water pollution indices show more serious pollution towards the river downstream. In particular, CPI and OPI reveal a high risk of eutrophication. Cluster analysis was applied to classify water monitoring points into different quality groups in order to provide a better understanding of the water status in the river. This study indicates that a combined water quality analysis could be an option for decision making water use purposes while its single index shows the current situation of water quality.
MColiPAT kit for early detection of coliforms in water
Authors: Tambi Ashish , Brighu Urmila , Gupta A. B. 
Published: January 2020

Abstract
Determining the microbial quality of drinking water by assessing the presence/absence (P/A) or enumeration of indicator bacteria continues to be widely practiced worldwide. However, rapid tests are required for microbiological water quality assessment so that the information is available in the shortest possible time for initiating a timely intervention. Traditional methods for the enumeration of indicator bacteria are not only expensive but also need trained personnel. We have developed a low-cost kit, MColiPAT, and have validated its application for detection of coliforms in drinking water using the IDEXX Colilert-18 Quanti tray method. MColiPAT kit medium was able to detect coliforms down to a level of 3.1 MPN/100 ml within 10.5 hours. The sensitivity and specificity of the kit were 95.45% and 100% respectively. MColiPAT is found to be reliable and accurate for the detection of coliforms in drinking water.
The Power of Matrix Factorization: Methods for Deconvoluting Genetic Heterogeneous Data at Expression Level
Authors: Liu Yuan , Wen Zhining , Li Menglong 
Published: January 2020

Background::
The utilization of genetic data to investigate biological problems has recently
become a vital approach. However, it is undeniable that the heterogeneity of original samples at the
biological level is usually ignored when utilizing genetic data. Different cell-constitutions of a sample
could differentiate the expression profile, and set considerable biases for downstream research. Matrix
factorization (MF) which originated as a set of mathematical methods, has contributed massively to
deconvoluting genetic profiles in silico, especially at the expression level.

Objective:
With the development of artificial intelligence algorithms and machine learning, the
number of computational methods for solving heterogeneous problems is also rapidly abundant.
However, a structural view from the angle of using MF to deconvolute genetic data is quite limited.
This study was conducted to review the usages of MF methods on heterogeneous problems of genetic
data on expression level.

Methods:
MF methods involved in deconvolution were reviewed according to their individual
strengths. The demonstration is presented separately into three sections: application scenarios, method
categories and summarization for tools. Specifically, application scenarios defined deconvoluting
problem with applying scenarios. Method categories summarized MF algorithms contributed to
different scenarios. Summarization for tools listed functions and developed web-servers over the latest
decade. Additionally, challenges and opportunities of relative fields are discussed.

Results and Conclusion:
Based on the investigation, this study aims to present a relatively global
picture to assist researchers to achieve a quicker access of deconvoluting genetic data in silico, further
to help researchers in selecting suitable MF methods based on the different scenarios.
Annotating Narrative Levels: Review of Guideline No. 8
Authors: McEnaney Tom 
Published: January 2020

“Let me tell you a story.” The proposed guidelines suggest that this phrase serve as the heuristic that readers supply at the beginning of any possible embedded narrative to identify a shift in narrative frames or levels. (The difference between “frame” and “level,” although perhaps confusing in the history of narratology, does not seem like an important distinction at this stage of the project.) This simple phrase, the author suggests, can replace a field of narrative theory they feel would “simply confuse my student annotators.” However simple the phrase might seem, however, it, in fact, conceals a number of key narratological issues: focalization, temporal indices, diction / register, person, fictional paratexts, duration, and, no doubt, others. The question for the guidelines is whether one can leapfrog the particularity of these issues if students use the above phrase to annotate texts with XML tags and produce operational scripts that identify the nested narratives. As it currently stands, students seem capable of learning the basic idea of nested narratives and tagging changes in narrative frames, but there are no real results to confirm the project’s success, as the author reports they are not yet able to confirm any inter-annotation agreement.
Cost–effectiveness analysis of ocriplasmin versus watchful waiting for treatment of symptomatic vitreomacular adhesion in the US
Authors: Khanani Arshad M , Dugel Pravin U , Haller Julia A , Wagner Alan L , Lescrauwaet Benedicte , Schmidt Ralph , Bennison Craig 
Published: January 2020

Aim:
Evaluate the cost–effectiveness of ocriplasmin in symptomatic vitreomacular adhesion (VMA) with or without full-thickness macular hole ≤400 μm versus standard of care.
Methods:
A state-transition model simulated a cohort through disease health states; assignment of utilities to health states reflected the distribution of visual acuity. Efficacy of ocriplasmin was derived from logistic regression models using Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole trial data. Model inputs were extracted from Phase III trials and published literature. The analysis was conducted from a US Medicare perspective.
Results:
Lifetime incremental cost–effectiveness ratio was US$4887 per quality-adjusted life year gained in the total population, US$4255 and US$10,167 in VMA subgroups without and with full-thickness macular hole, respectively.
Conclusion:
Ocriplasmin was cost effective compared with standard of care in symptomatic VMA.
Técnica híbrida (TH) versus estándar(TS) en la punción con aguja fina guiada por ecoendoscopia para lesiones sólidas del páncreas
Authors: Gómez Zuleta Martín Alonso , Ruíz Morales Oscar Fernando , Lúquez Minndiola Adán José 
Published: January 2020

La ultrasonografía endoscópica (USE) se usa ampliamente para evaluar enfermedades pancreatobiliares, especialmente masas pancreáticas. La USE tiene una buena capacidad para detectar masas pancreáticas, pero no es suficiente para el diagnóstico diferencial de varios tipos de lesiones. La aspiración endoscópica con aguja fina guiada por ultrasonido (USE-PAF) es el método de diagnóstico de elección para masas pancreáticas y su precisión se afecta por diversos métodos de punción.
Materiales y métodos: nuestro objetivo fue evaluar el rendimiento diagnóstico de la técnica de succión estándar (TS) versus la técnica húmeda híbrida (TH) en el estudio de lesiones sólidas en páncreas, utilizando un diseño prospectivo, con ocultación única, aleatorizado y controlado, que incluye a pacientes con diagnóstico de lesión sólida en páncreas a los que se realizó USE-PAF desde mayo de 2014 a junio de 2016.
Resultados: en total incluimos 65 pacientes, 34 (52,3%) se asignaron a USE-PAF con TH y 31 (47,7%) pacientes a USE-PAF con TS. Se encontró que la frecuencia relativa porcentual respecto a la técnica de punción en la USE-PAF en lesiones sólidas de páncreas, que permite obtener la cantidad de tejido adecuado para el diagnóstico citológico, fue de 85,2% para la TH y 71% para la TS, con un OR de 2,35 (IC 95%; 1,2-4,7) a favor de la TH.
Conclusión: este estudio sugiere que la TH es superior a la TS en el diagnóstico de las lesiones sólidas del páncreas, por lo cual, dado que la implementación de esta técnica no aumenta costos y es muy sencilla, sugerimos que sea la técnica de elección cuando se necesita puncionar una lesión sólida.
Integration of digital maxillary dental casts with 3D facial images in orthodontic patients:
Authors: Xiao Zhuoxing , Liu Zijin , Gu Yan 
Published: January 2020

ABSTRACT

Objective
To evaluate three-dimensional (3D) accuracy and reliability of nonradiographic dentofacial images integrated with a two-step method.

Methods
3D facial images, cone-beam computed tomography (CBCT) images and digital maxillary dental casts were obtained from 20 pre-orthodontic subjects. Digital dental casts were integrated into 3D facial images using a two-step method based on the anterior tooth area. 3D coordinate values of five dental landmarks were identified in both dentofacial images and CBCT images. The accuracy of the integration method was assessed with paired t-tests between dentofacial images and CBCT-based reference standards. Intraclass correlation coefficients (ICCs) were assessed for the reliability of dentofacial images and CBCT-based images. Analysis of variance and Kruskal-Wallis tests evaluated the accuracy of the method in different dimensions.

Results
There was no statistical difference between dentofacial images and CBCT reference standards in both translational and rotational dimensions (P &gt; .05). Translational mean absolute errors for full dentitions were within 0.42 mm and ICCs were over 0.998 in x, y, and z directions. Rotational mean absolute errors for full dentitions were within 0.92° and ICCs over 0.734 in pitch, yaw, and roll orientations. Integration errors were significantly greater in the first molar, z-translation, and pitch rotation (P &lt; .05).

Conclusions
Integrating 3D dentofacial images with the two-step method is precise and acceptable for clinical diagnostics and scientific purposes. Errors were greater in the molar region, z-translation, and pitch rotation.