bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of different water pH on hatching and survival rates of African catfish Clarias gariepinus (Pisces: Clariidae)
Authors: Marimuthu Kasi , Palaniandya Harysooria , Muchlisin Zainal A. 
Published: November 2019

Water quality parameters influence the growth and survival of different stages of fishes and hence determining the optimal water quality variables is greatly important for any aquaculture farming. Among the variables, water pH is considered the key factors and plays an important role in the maintenance of the homeostasis in fishes. A study was conducted to determine the influence of different water pH on the incubation period, hatching rate and survival rate of African catfish (Clarias gariepinus) larvae. The fertilized eggs were incubated at 28.0 ± 1.0 °C with different levels of water pH ranging from 3-10. Twenty four pH levels were tested for incubation period and egg hatchability while 15 pH levels were tested for larval survivability in a completely randomized design with three replicates for each treatment. Just hatched larvae were used for this study and the effect was observed until 72 h post-hatching. Water pH was maintained by the addition of NaOH or H2SO4solutions. The incubation times of fertilized eggs were recorded to be 23.5–25.0 h at pH levels of 6.1–8.8. The increased incubation time was noticed at the rest of the acidic and alkaline pH levels. Significantly highest hatching rate was observed at the pH levels of 6.7–7.6 compared to those at lower and higher pH levels (P0.05). However, no significant differences (P0.05) were recognized in the hatching rates at the pH levels of 6.7 – 7.6. No hatching occurred at low pH levels between 3.1 and 3.4 and at high pH of 10. After 72 h of exposure to different pH levels, no larvae survived at pH levels below 4.5 and above 9.0. Highest larval survival (98%) was observed at pH 7.0 followed by 94% at pH 7.5 and 92% at pH 6.5. The results obtained in the present study revealed embryos and larvae can survive and tolerate to a low pH level of 3.7 and 4.5, respectively but the survival rates decreased with decreasing pH levels. Therefore, a water pH level of 6.7–7.5 is highly recommended for optimal hatching and highest larval viability of C. gariepinus.
Somatoendocrine disorders in nervous anorexia
Authors: Chazova T. Ye. , Kalinchenko S. Yu. 
Published: November 2019

Anorexia nervosa (AN) is expressed in the extremely stubborn desire to lose weight through targeted, long-term self-restraint in food, sometimes accompanied by intense physical exercise or taking large doses of a laxative. If it is impossible to withstand prolonged starvation, patients resort to a method such as inducing artificial vomiting.
AN is a pathology characteristic of adolescent girls and young girls, although it can sometimes occur in males of puberty or adolescence. AN is more common at the age of 15-25 years. The incidence among women is on average 10 times higher than among men. There is no information on the prevalence of AN in our country. According to foreign authors, the frequency of AN is 112 per 100,000 of the population. However, these data are underestimated, since only patients with severe, protracted forms of the course of AN go to the hospital and are subject to accounting. Patients with "mild" forms of AN remain outside the field of vision of doctors.
The beginning of a scientific study of AN was laid by W. Gull (1868) and E.-Ch. Laseque (1873). However, despite the increasing number of studies devoted to this interesting problem, AN still causes numerous discussions regarding its etiology, pathogenesis, and neuroendocrine disorders, and methods for their correction.
In this review, we tried to summarize the available data of recent years. One of the first reviews on the nature of neuroendocrine shifts in AN was made in 1984.
Enhancement of Glass Production Rate in Joule Heated Ceramic Melter
Authors: Suneel G. , Kaushik Chetan P. , Satya Sai P. M. , Gayen J. K. , Ravi K. V. 
Published: November 2019

Abstract
In this research work, experimental studies and numerical simulation of Joule Heated Ceramic Melter (JHCM) used for vitrification of radioactive liquid waste (RLW) were carried out. The isolation of the long-lived radioactive isotopes by fixing them in suitable host matrix is the only practical approach adopted for conditioning of highly radioactive waste generated from the nuclear fuel cycle. RLW and preformed glass beads are added simultaneously on a molten glass pool maintained at 1000 °C in JHCM to form a product that is qualified for long term storage. The sequence and kinetics of different reactions taking place in JHCM were identified and calculated by carrying out Thermogravimetric Analysis of the radioactive species present in RLW at different heating rates. The effects of these constituents on the melter throughput and quality of the Vitrified Waste Product (VWP) produced were assessed. The foam generated during vitrification process has a major influence on the design of melters. The amount of foam generated was quantified and its influence on glass production rate was analyzed. Melt rate limitations were determined for JHCM based on the measured thermo-physical properties. Minimum residence time required for producing product of the desired specification is determined. A model is developed for determining the glass melting rates. Experiments were carried out for generating data required for validation of the model. The model predictions are compared with experimental results. The factors affecting the product throughput and quality are identified with an objective of reducing the residence time of the product thereby increasing the throughput. The effect of agitation on the rate of melting of glass was determined.
Isomorphic co-expression of nominal predication subdomains: An Indo-Iranian case study
Authors: Shirtz Shahar 
Published: November 2019

AbstractThis paper explores the isomorphic co-expression of nominal predication subdomains across ten Indo-Iranian languages. Unlike many previous studies, this paper takes into account combinations of structural coding means, and does not limit its scope to the copula. Further this paper does not limit its attention to “primary” strategies and also takes into account “secondary” or “rare” attested strategies. Then, this paper presents a method based on bipartite graphs to visualize and compare patterns by which two subdomains of nominal predication are co-expressed by isomorphic combinations of coding means. The results show that every pair of subdomains is co-expressed at least somewhere across the family. In five of the ten languages studied here, predicative possession is expressed by the coding means usually used for equation or proper inclusion, but never as the main strategy to express predicative possession. This suggests that unlike what scholars have so far assumed, such situations may be crosslinguistically common but intra-linguistically rare. Another surprising result is the rare isomorphic co-expression of predicative possession and predicate location (i. e. with completely identical morphosyntax), but the much more common co-expression of predicative possession and existence. Altogether, this paper highlights the importance of taking into account intra-linguistic variation in morphosyntactic comparison.
Si metasurface half-wave plates demonstrated on a 12-inch CMOS platform
Authors: Dong Yuan , Xu Zhengji , Li Nanxi , Tong Jinchao , Fu Yuan Hsing , Zhou Yanyan , Hu Ting , Zhong Qize , Bliznetsov Vladimir , Zhu Shiyang , Lin Qunying , Zhang Dao Hua , Gu Yuandong , Singh Navab 
Published: November 2019

Abstract
Half-wave plate (HWP) is one of the key polarization controlling devices in optical systems. The conventional HWPs based on birefringent crystals are inherently bulky and difficult to be monolithically integrated with other optical components. In this work, metasurface-based HWPs with high compactness are demonstrated on a 12-inch silicon complementary metal-oxide-semiconductor platform. Three-dimensional finite difference time domain simulation is used to design the nanostructure and investigate the impact of fabrication process variation on the device performance. In addition, the cross- and co-polarization transmittance (T
cross and T
co) of the HWPs located at different wafer locations are characterized experimentally. The peak T
cross and valley T
co values of 0.69 ± 0.053 and 0.032 ± 0.005 are realized at the wavelength around 1.7 μm, respectively. This corresponds to a polarization conversion efficiency of 95.6% ± 0.8%.
Serological ferritin, 100A12, procalcitonin and APACHEII score in prediction the prognosis of acute respiratory distress syndrome
Authors: Chen Xubin , Zhou Jiancang , Xu Liangfei , Chen Ling , Mao Pingan , Yang Xuelin 
Published: November 2019

Abstract

Objective The aim of the present work was to investigate the prognostic value of serological ferritin, 100A12, procalcitonin (PCT) and APACHEII score in predicting death risk for patients with acute respiratory distress syndrome (ARDS).

Methods Forty eight ARDS patients were recruited from Feb. 2016 to Jan. 2019 from Lishui People’s Hospital. According to their prognosis (survival or death within 28 days), these 48 patients were further divided into the survival group (n=28) and death group (n=20). The serological levels of S100A12, PCT and ferritin of the 48 ARDS patients were examined within 24 hours after hospitalization. Demographic characteristics, serum S100A12, PCT and ferritin were compared between the two groups, and diagnostic analysis was performed to evaluate the clinical efficacy of these markers in predicting the death of ARDS patients.

Results The serum S100A12, ferritin and APACHEII scores of the death group were significantly higher than those of the survival group (p<0.05). However, serum PCT levels were not statistically different between the two groups (p>0.05). The death prediction sensitivity for serum S100A12, PCT, ferritin and APACHEII score were 65.0 (40.78-84.61)%, 60.00(36.05-80.88) %,75.0(50.90-91.34)% and 85.0(62.11-96.79)% respectively. The death prediction specificity for serum S100A12, PCT, ferritin and APACHEII score were 75.0(55.13-89.31)%, 60.00(36.05-80.88)%, 64.29(44.07-81.36)% and 82.14(63.11-93.94)%, respectively. The area under the ROC curve (AUC) for serum S100A12, PCT, ferritin and APACHEII score were 0.68(0.51-0.84), 0.63(0.46-0.79), 0.71(0.56-0.86) and 0.91(0.83-0.99) respectively.

Conclusion Serological ferritin, 100A12, PCT and APACHEII scores can be used as biomarkers to predict the death risk of ARDS patients.
Comparative Study of Photocarrier Dynamics in CVD-deposited CuWO4, CuO, and WO3 Thin Films for Photoelectrocatalysis
Authors: Hirst James , Müller Sönke , Peeters Daniel , Sadlo Alexander , Mai Lukas , Reyes Oliver Mendoza , Friedrich Dennis , Mitoraj Dariusz , Devi Anjana , Beranek Radim , Eichberger Rainer 
Published: November 2019

Abstract
The temporal evolution of photogenerated carriers in CuWO4, CuO and WO3 thin films deposited via a direct chemical vapor deposition approach was studied using time-resolved microwave conductivity and terahertz spectroscopy to obtain the photocarrier lifetime, mobility and diffusion length. The carrier transport properties of the films prepared by varying the copper-to-tungsten stoichiometry were compared and the results related to the performance of the compositions built into respective photoelectrochemical cells. Superior carrier mobility was observed for CuWO4 under frontside illumination.
Abnormal Photic Entrainment to Phase-Delaying Stimuli in the R6/2 Mouse Model of Huntington's Disease, despite Retinal Responsiveness to Light
Authors: Ouk Koliane , Aungier Juliet , Ware Michelle , Morton A. Jennifer 
Published: November 2019

AbstractThe circadian clock located in the suprachiasmatic nucleus (SCN) in mammals entrains to ambient light via the retinal photoreceptors. This allows behavioral rhythms to change in synchrony with seasonal and daily changes in light period. Circadian rhythmicity is progressively disrupted in Huntington’s disease (HD) and in HD mouse models such as the transgenic R6/2 line. Although retinal afferent inputs to the SCN are disrupted in R6/2 mice at late stages, they can respond to changes in light/dark cycles, as seen in jet lag and 23 h/d paradigms. To investigate photic entrainment and SCN function in R6/2 mice at different stages of disease, we first assessed the effect on locomotor activity of exposure to a 15 min light pulse given at different times of the day. We then placed the mice under five non-standard light conditions. These were light cycle regimes (T-cycles) of T21 (10.5 h light/dark), T22 (11 h light/dark), T26 (13 h light/dark), constant light, or constant dark. We found a progressive impairment in photic synchronization in R6/2 mice when the stimuli required the SCN to lengthen rhythms (phase-delaying light pulse, T26, or constant light), but normal synchronization to stimuli that required the SCN to shorten rhythms (phase-advancing light pulse and T22). Despite the behavioral abnormalities, we found thatPer1and c-fosgene expression remained photo-inducible in SCN of R6/2 mice. Both the endogenous drift of the R6/2 mouse SCN to shorter periods and its inability to adapt to phase-delaying changes will contribute to the HD circadian dysfunction.
Large cell neuroendocrine carcinoma with a solitary brain metastasis and low Ki-67: a unique subtype
Authors: Hermans B C M , Derks J L , Groen H J M , Stigt J A , van Suylen R J , Hillen L M , van den Broek E C , Speel E J M , Dingemans A-M C 
Published: November 2019

Introduction
Stage IV large cell neuroendocrine carcinoma (LCNEC) of the lung generally presents as disseminated and aggressive disease with a Ki-67 proliferation index (PI) 40–80%. LCNEC can be subdivided in two main subtypes: the first harboring TP53/RB1 mutations (small-cell lung carcinoma (SCLC)-like), the second with mutations in TP53 and STK11/KEAP1 (non-small-cell lung carcinoma (NSCLC)-like). Here we evaluated 11 LCNEC patients with only a solitary brain metastasis and evaluate phenotype, genotype and follow-up.

Methods
Eleven LCNEC patients with solitary brain metastases were analyzed. Clinical characteristics and survival data were retrieved from medical records. Pathological analysis included histomorphological analysis, immunohistochemistry (pRB and Ki-67 PI) and next-generation sequencing (TP53, RB1, STK11, KEAP1 and MEN1).

Results
All patients had N0 or N1 disease. Median overall survival (OS) was 12 months (95% confidence interval (CI) 5.5–18.5 months). Mean Ki-67 PI was 59% (range 15–100%). In 6/11 LCNEC Ki-67 PI was ≤40%. OS was longer for Ki-67 ≤40% compared to >40% (17 months (95% CI 11–23 months) vs 5 months (95% CI 0.7–9 months), P = 0.007). Two patients were still alive at follow-up after 86 and 103 months, both had Ki-67 ≤40%. 8/11 patients could be subclassified, and both SCLC-like (n = 6) and NSCLC-like (n = 2) subtypes were present. No MEN1 mutation was found.

Conclusion
Stage IV LCNEC with a solitary brain metastasis and N0/N1 disease show in the majority of cases Ki-67 PI ≤40% and prolonged survival, distinguishing them from general LCNEC. This unique subgroup can be both of the SCLC-like and NSCLC-like subtype.
SCHWANNOMA İLE KARIŞAN MALİGN SOLİTER FİBRÖZ TÜMÖR-BİR OLGU SUNUMU
Authors: AKIN Süleyman Emre , ESME Hıdır , DURAN Ferdane Melike 
Published: November 2019

Plevranın soliter fibröz tümörleri; tüm plevral
tümörler içerisinde %5’ den az görülür. %10-20 oranında malign olabilen bu
tümörler , çoğunlukla semptom vermeyip , toraks içerisinde büyük boyutlara
ulaşabilen iyi sınırlı kitlelerdir. Tanı ve tedavide komplet rezeksiyon
gereklidir. Nüks ve malign transformasyon
riski vardır. Bu çalışmada, kliniğimizde sol hemitoraksta kitle nedeni ile
opere edilen ve postoperatif patolojik tanısında çelişki görülen oldukça nadir
rastlanan bu olgu literatür bilgileri eşliğinde sunulmuştur.
Clinico-biochemical and morphological mapping in chronic liver diseases in patients of the senior age group
Authors: Stolov S. V. , Yamshchikova T. Yu. , Garan T. A. , Kochergina T. A. , Schwazman Z. D. , Makarova O. V. , Ugleva E. M. 
Published: November 2019

Diagnosis of chronic liver diseases in elderly patients has its own features due to polymorbidity, multiple organ failure, being subtle the course of the disease.
The purpose of the study was to identify correlations of inflammation biochemical parameters and hepatocellular failure with histology in chronic hepatitis (CH) and liver cirrhosis (LC) in elderly patients.
Materials and methods. The study included medical records of patients with chronic liver disease (CLD) who died in the Clinical Hospital for War Veterans of Saint Petersburg between 2009 and 2015 (with the average age of 81 year). The diagnosis of chronic hepatitis (45 cases) and chronic cirrhosis (54 cases) was confirmed by postmortem examination. Morphological changes in the liver were described according to Knodell creteria. The degree of inflammatory activity in the liver was evaluated in points (0.1 to 3.0) depending on the level of AST, ALT, -globulin, alkaline phosphatase, -GTP, bilirubin. For similar scoring severity hepatocellular insufficiency (0.13.0) considered total protein, albumin, prothrombin index, fibrinogen. For cirrhotic patients the Child-Pugh criteria were also used.
Results. Chronic liver disease (CLD) hepatitis and cirrhosis of the elderly is detected in 1,5% of cases. In most cases, CLD develop secondary to diseases of the cardiovascular system, and are accompanied by subtle symptoms, which limits their life-time diagnosis. The integral evaluation of the process activity degree according to biochemical indices was significantly higher in the group of chronic hepatitis than in the group of liver cirrhosis. Correlations of the inflammation bichemical parameters (AST and / or ALT, -globulin, alkaline phosphatase, -GTP) having a degree of Knodell Histological Activity Group chronic hepatitis and cirrhosis have not been established. The study established correlation of histological activity with total bilirubin levels in both groups of CLD. Integral assessment of hepatocellular deficiency by biochemical indicators of liver cirrhosis group was higher than in the group of chronic hepatitis.
Galant – new sort of tomato for the Far East
Authors: Kuzmitskaya Galina A. 
Published: November 2019

Relevance. Tomato is one of the most spreaded vegetable cultures in Khabarovsk Territory. Presence of the favourable weather conditions in the region, high ecological plasticity of tomato sorts promote the tomato cultivation in open and protected ground everywhere and in large areas. The main cause of crop failure or large losses of tomatoes in the Far East is a complex, unpredictable, not meeting anywhere else in Russia the monsoon climate causing a strong waterlogging observed almost every year in July-August, the period of the main tomato harvest forming. Such weather conditions promote the development of main diseases of the solanaceous cultures, and their most aggressive races often appear. Therefore a high natural infectious background and a sharply variable hydrothermal regime are the main limiting factors in the cultivation of tomatoes in the Khabarovsk Territory.Methods. Work on the creation of a new variety with the given parameters was started in 2007 by conducting intervarietal crossings between Volgogradsky 5/95 and Zarya Vostoka varieties, followed by multiple selections against a natural infectious background. The early ripening variety of Zarya Vostoka is a local selection variety, was used in the breeding process as an early maturity donor, and Volgogradsky 5/95, a stem type of plant. The main method of breeding work to create new varieties of tomato was analytical with continuous selection. All the necessary phenological, biometric and phytopathological observations and counts according to methods generally accepted in this culture. The purpose of our research was to create a new strain tomato variety with a short period of vegetation, forming the harvest of fruit before the appearance and spread of the disease and high productive potential.Results. This publication presents the information about the new local tomato sort Galant. This sort was received by inter-sort hybridization between the stem sort Volgogradsky 5/95 and local early ripening sort Zarya Vostoka. The sort was selected as a result long-term selection on the natural infectious background with the assessment by progeny of promising lines for a complex of morpho-biological and economically valuable traits in monsoon climate conditions of Priamurye. The new sort is different from other studied non-district and local sorts by fastripeness, high productivity, resistance to main diseases and also by stem type of plant.
Niños migrantes en México y el cumplimiento del derecho humano a la educación
Authors: Cornelio Landero Rosa 
Published: November 2019

El territorio mexicano se encuentra en la mira de las organizaciones internacionales que protegen los derechos humanos, ante la alza de flujo migratorio que van a los EEUU., los niños migrantes y su situación en el territorio mexicano que viajan en caravanas solos o con sus padres, son los más vulnerables por su corta edad a ser víctimas de violencia, trata de personas y abuso sexual, por lo que son los que requieren mayor atención y ayuda humanitaria, no discriminarlos por ninguna circunstancia; la UNICEF México es un organismo es el organismo encargado de buscar el trato digno a los niños y que se le otorgue su derecho humano a la salud, a la educación, derechos que se encuentran establecidos en las normas jurídicas mexicanas, por lo que es importante que el Estado mexicano cuente con políticas públicas en materia del derecho humano a la educación de los migrantes.
The precursor for nerve growth factor (proNGF) is not a serum or biopsy-rinse biomarker for thyroid cancer diagnosis
Authors: Rowe Christopher W , Faulkner Sam , Paul Jonathan W , Tolosa Jorge M , Gedye Craig , Bendinelli Cino , Wynne Katie , McGrath Shaun , Attia John , Smith Roger , Hondermarck Hubert 
Published: November 2019

Abstract
Background: Nerves and neurotrophic growth factors are emerging promoters of cancer growth. The precursor for Nerve Growth Factor (proNGF) is overexpressed in thyroid cancer, but its potential role as a clinical biomarker has not been reported. Here we have examined the value of proNGF as a serum and biopsy-rinse biomarker for thyroid cancer diagnosis. Methods: Patients presenting for thyroid surgery or biopsy were enrolled in separate cohorts examining serum (n=204, including 46 cases of thyroid cancer) and biopsy-rinse specimens (n=188, including 26 cases of thyroid cancer). ProNGF levels in clinical samples were analysed by ELISA. Multivariate statistical analyses testing for potential confounders were used to compare proNGF levels with clinicopathological parameters. Results: ProNGF was not detected in the majority of serum samples 176/204 (86%) and the detection of proNGF was not associated with thyroid cancer diagnosis. In the few cases where proNGF was detected in the serum, thyroidectomy did not affect proNGF concentration, demonstrating that the thyroid was not the source of serum proNGF. Intringuingly, an association between hyperthyroidism and serum proNGF was observed (OR 3.3, 95%CI 1.6-8.7 p=0.02). In biopsy-rinse, proNGF was detected in 73/188 (39%) cases, with no association between proNGF and thyroid cancer. However, a significant positive association between follicular lesions and biopsy-rinse proNGF was found (OR 3.3, 95% CI 1.2-8.7, p=0.02). Conclusions: ProNGF levels in serum and biopsy-rinse are not increased in thyroid cancer and therefore proNGF is not a clinical biomarker for this condition.