bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of big data analytics on improvement of corporate social/green performance
Authors: Mishra Bibhu Prasad , Biswal Bibhuti Bhusan , Behera Ajay Kumar , Das Harish Chandra 
Published: September 2020

PurposeIn spite of the fact that literature shows that big data analytics (BDA) pass on a distinct corporate ability, little is thought about their performance impacts, specifically logical conditions. Establishing this research in the dynamic capability view (DCV) and corporate culture and dependent on an sample of 310 Indian production industries, the purpose of this paper is to experimentally study the impacts of BDA on corporate social performance (CSP) and corporate green performance (CGP) using variance-based structural equation modeling (for example, PLS).Design/methodology/approachA questionnaire was used to accumulate data sets to examine research hypothesis. The authors pre-examined the survey with six scholastics and six directors from production firms in India. With the help of their sources of data, the authors have adjusted their wordings to improve the transparency and guarantee that length of the survey is accurate. Finally, the questionnaire was prepared for definite data collection.FindingsThe authors conclude that BDA has noteworthy effect on CSP/CGP. Notwithstanding, the authors did not find proof for directing role of flexible direction and control direction in the connections among BDA and CSP/CGP. This research offers a more nuanced comprehension of the performance ramifications of BDA, and in this way, it is tending to the critical inquiries of how and when BDA can improve in supply chains.Originality/valueThis investigation makes helpful commitments to the BDA research and its effect on CSP/CGP. To the authors’ best of information, this is the first hypothesis-focused approach to clarify the effect of BDA on ecological and social supportability. Second, this investigation likewise gives empirical proof that BDA impact on CSP/CGP and is free of flexible or control direction of the industry.
Demande extérieure et offre agricole de long terme: Cas des noix de cajou dans l'Union Economique et Monétaire Ouest‐Africaine (UEMOA)
Authors: Oloukoi Laurent 
Published: September 2020

RésuméL'objectif de ce papier est de vérifier si les pays de l'UEMOA ont atteint le seuil critique d'offre de noix de cajou où la demande extérieure de ce produit serait une contrainte. Le modèle de Thirlwall (1979) est utilisé avec des données allant de 1980 à 2016. Les résultats révèlent, entre autres, que: (i) le seuil critique de croissance de l'offre de cajou dans l'UEMOA est supérieur à l'offre observée, (ii) les pays de l'UEMOA offrent seulement 58% de leur seuil critique en matière de noix de cajou, (iii) la demande extérieure de noix de cajou n'est pas une contrainte. La stratégie de development de la filière cajou ne sera donc pas celle préconisée par la théorie de la croissance contrainte par l’équilibre extérieur.
Educational Goods Reconsidered: A Response
Authors: Brighouse Harry , Ladd Helen F , Loeb Susanna , Swift Adam 
Published: September 2020

Abstract
We gratefully reply to our five commentators, responding to their criticisms and comments under the following headings: parochialism and curriculum; rationality and truth; production and distribution; perfectionism, decision-making and disagreement; adultism and parents' interests; non-consequential educational goods; and self-education.
Introduction and application of a composite insect trap for the National Ecosystem Survey of Korea
Authors: Han Yong‐Gu , Hong Eui jeong , Kim Do‐Sung , Kim Chulgoo , Cha Jin Yeol 
Published: September 2020

AbstractThis study aimed to establish the best applicable method for the National Ecosystem Survey (NES) guidelines by (i) verifying the efficiency of an insect trap that combined the Malaise trap, flight intercept trap, and pitfall trap (MFP trap) as part of the improvement for the terrestrial insect field in the fifth NES, and (ii) comparing the result with the currently used Malaise trap and pitfall trap (MP traps). We found that the efficiency of attaining species diversity was much higher with the added flight intercept trap function than the current Malaise trap alone for flying insect collection. For collecting ground insects, the efficiency of attaining species diversity of the pitfall trap from the MFP trap was lower than that from the MP trap. Besides, the Malaise trap of the MP trap showed superior efficiency than that of the MFP trap in species diversity. The results suggested that modification, supplementation, and re‐testing should be performed by analyzing various factors such as the trap material, barrier size, capturing container inlet, and mesh size, with consideration of the design of the current Malaise trap. Therefore, in survey‐based research, which aims at identifying insects species diversity and inhabiting status—such as the NES, it is necessary to introduce the MFP trap with the flight intercept trap function added to the Malaise trap function, and for the pitfall trap function of the MFP trap, it can be operated as a separate trap from the MFP trap.
Regionalization of Default Parameters for Urban Stormwater Quality Models
Authors: Bell Colin D. , Wolfand Jordyn M. , Hogue Terri S. 
Published: September 2020

AbstractAccurate parameterization of water quality routines within stormwater models can improve simulation, prediction of system behavior, and lead to more informed decision making. This work recognizes that factors controlling runoff concentrations and treatment in stormwater best management practices (BMPs) vary with region, assumes region is a proxy for these factors, and seeks to improve tool parameterization by (1) identifying a regionalization scheme that best explains variability in national datasets of runoff water quality and BMP performance, (2) generating region‐specific model parameter values, and (3) demonstrating how model output varies when using national vs. regional parameters. Of the four regionalization schemes tested, the National Climatic Data Center’s Regions best explained variance in pollutant runoff concentrations from the National Stormwater Quality Database, accounting for more data variability (1.1%) than the watershed’s land use (0.4%). For BMP performance extracted from the International Stormwater BMP Database, the United States (U.S.) Environmental Protection Agency’s Rain Zones explained the most variance (1.1%), which is one‐fifth of the variance explained by BMP type (5.0%). These results were used to generate regional parameter lookup tables for stormwater quality modeling. Test cases from the 100 most populous cites in the U.S. showed national parameters predicted BMP effluent concentrations that were 15% lower than the regional parameters for five pollutants.
Risk factors correlated with immunosuppressant discontinuation in antineutrophil cytoplasmic antibody‐associated vasculitis patients
Authors: Murosaki Takamasa , Sato Takeo , Nagatani Katsuya , Sato Kojiro , Minota Seiji 
Published: September 2020

AbstractAimThe use of an immunosuppressant is recommended as a treatment for remission induction in anti‐neutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV). However, the immunosuppressant is sometimes discontinued due to an adverse event. We sought to identify the cause and risk factors for immunosuppressant discontinuation in patients with AAV receiving remission induction treatment.MethodsWe retrospectively analyzed the cases of AAV patients treated in 2005‐2016 with immunosuppressants to induce remission. We defined “discontinuation” as stopping, switching, or delaying immunosuppressant administration due to adverse events. We performed a multivariate analysis to identify risk factors for immunosuppressant discontinuation.ResultsWe identified 50 patients treated with an immunosuppressant for remission induction: cyclophosphamide was used in 45 patients (90%), methotrexate in 4 (8%), and cyclosporine A in 1 patient (2%). Among them, 26 patients (52%) underwent discontinuation of the immunosuppressant. Infection and myelosuppression were the major causes of discontinuation. Multivariate Cox proportional hazards regression analysis revealed that a cumulative dose of prednisolone ≥ 2000 mg (hazard ratio [HR] =2.18, 95% confidence interval [CI] =1.37‐3.70, P < .001), performance status of 3‐4 (HR = 1.80, 95% CI = 1.07‐3.03, P = .027), and oral cyclophosphamide (HR = 1.81, 95% CI = 1.11‐2.97, P = .018) were independent risk factors correlated with immunosuppressant discontinuation.ConclusionPhysicians should be aware of risk factors predicting immunosuppressant discontinuation when treating AAV patients with an immunosuppressant.
Reliably predicting pollinator abundance: Challenges of calibrating process‐based ecological models
Authors: Gardner Emma , Breeze Tom D. , Clough Yann , Smith Henrik G. , Baldock Katherine C. R. , Campbell Alistair , Garratt Michael P. D. , Gillespie Mark A. K. , Kunin William E. , McKerchar Megan , Memmott Jane , Potts Simon G. , Senapathi Deepa , Stone Graham N. , Wäckers Felix , Westbury Duncan B. , Wilby Andrew , Oliver Tom H. 
Published: September 2020

Abstract

Pollination is a key ecosystem service for global agriculture but evidence of pollinator population declines is growing. Reliable spatial modelling of pollinator abundance is essential if we are to identify areas at risk of pollination service deficit and effectively target resources to support pollinator populations. Many models exist which predict pollinator abundance but few have been calibrated against observational data from multiple habitats to ensure their predictions are accurate.

We selected the most advanced process‐based pollinator abundance model available and calibrated it for bumblebees and solitary bees using survey data collected at 239 sites across Great Britain. We compared three versions of the model: one parameterised using estimates based on expert opinion, one where the parameters are calibrated using a purely data‐driven approach and one where we allow the expert opinion estimates to inform the calibration process.

All three model versions showed significant agreement with the survey data, demonstrating this model's potential to reliably map pollinator abundance. However, there were significant differences between the nesting/floral attractiveness scores obtained by the two calibration methods and from the original expert opinion scores.

Our results highlight a key universal challenge of calibrating spatially explicit, process‐based ecological models. Notably, the desire to reliably represent complex ecological processes in finely mapped landscapes necessarily generates a large number of parameters, which are challenging to calibrate with ecological and geographical data that are often noisy, biased, asynchronous and sometimes inaccurate. Purely data‐driven calibration can therefore result in unrealistic parameter values, despite appearing to improve model‐data agreement over initial expert opinion estimates. We therefore advocate a combined approach where data‐driven calibration and expert opinion are integrated into an iterative Delphi‐like process, which simultaneously combines model calibration and credibility assessment. This may provide the best opportunity to obtain realistic parameter estimates and reliable model predictions for ecological systems with expert knowledge gaps and patchy ecological data.
A Call to Action: A Systematic Review Examining the Failure to Include Females and Members of Minoritized Racial/Ethnic Groups in Clinical Trials of Pharmacological Treatments for Alcohol Use Disorder
Authors: Schick Melissa R. , Spillane Nichea S. , Hostetler Katherine L. 
Published: September 2020

AbstractAlcohol use disorder (AUD) presents a significant public health concern given the high prevalence estimates and numerous deleterious‐associated consequences. The FDA currently has approved 3 pharmacological treatments for alcohol use disorder: acamprosate, naltrexone, and disulfiram. Previous research suggests that there may exist differences in the prevalence of and outcomes related to AUD across sex and racial/ethnic groups. Other work indicates that there may be differences in the efficacy of existing pharmacological treatments for AUD across demographic groups. The purpose of the present study was to examine the inclusion of women and members of minoritized racial/ethnic groups in published randomized clinical trials of pharmacological treatments for alcohol use disorder since 1994, in accordance with the NIH Revitalization Act of 1993. PubMed was systematically searched using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) statement. The initial search located 842 articles. After exclusion of ineligible articles, 102 remained for analysis. Of those included in the review, only 11.8% reported full sex and racial/ethnic characteristics of their study participants. Of the total sample, 6 articles were specifically examining 1 racial/ethnic group, and 11 were specifically examining 1 sex. Two articles (2.2%) did not report information regarding the sex breakdown of their participants, while 47 (49.0%) did not report any information regarding the racial/ethnic breakdown of their sample. Despite guidelines set forth by NIH, only 5.9% of articles conducted subgroup analyses to examine differences in treatment outcomes by sex or race/ethnicity, and only 16.7% of articles included considerations related to cultural inclusion when discussing study limitations. These results varied by medication type. Results suggest that considerably greater efforts must be put forth by the larger scientific community regarding the inclusion, analysis, and reporting of data focused on women and non‐White racial and ethnic groups.
Accuracy of serological testing for SARS‐CoV‐2 antibodies: First results of a large mixed‐method evaluation study
Authors: Brigger Daniel , Horn Michael P. , Pennington Luke F. , Powell Abigail E. , Siegrist Denise , Weber Benjamin , Engler Olivier , Piezzi Vanja , Damonti Lauro , Iseli Patricia , Hauser Christoph , Froehlich Tanja K. , Villiger Peter M. , Bachmann Martin F. , Leib Stephen L. , Bittel Pascal , Fiedler Martin , Largiadèr Carlo R. , Marschall Jonas , Stalder Hanspeter , Kim Peter S. , Jardetzky Theodore S. , Eggel Alexander , Nagler Michael 
Published: September 2020

AbstractBackgroundSerological immunoassays that can identify protective immunity against SARS‐CoV‐2 are needed to adapt quarantine measures, assess vaccination responses, and evaluate donor plasma. To date, however, the utility of such immunoassays remains unclear. In a mixed‐design evaluation study, we compared the diagnostic accuracy of serological immunoassays that are based on various SARS‐CoV‐2 proteins and assessed the neutralizing activity of antibodies in patient sera.MethodsConsecutive patients admitted with confirmed SARS‐CoV‐2 infection were prospectively followed alongside medical staff and biobank samples from winter 2018/2019. An in‐house enzyme‐linked immunosorbent assay utilizing recombinant receptor‐binding domain (RBD) of the SARS‐CoV‐2 spike protein was developed and compared to three commercially available enzyme‐linked immunosorbent assays (ELISAs) targeting the nucleoprotein (N), the S1 domain of the spike protein (S1), and a lateral flow immunoassay (LFI) based on full‐length spike protein. Neutralization assays with live SARS‐CoV‐2 were performed.ResultsOne thousand four hundred and seventy‐seven individuals were included comprising 112 SARS‐CoV‐2 positives (defined as a positive real‐time PCR result; prevalence 7.6%). IgG seroconversion occurred between day 0 and day 21. While the ELISAs showed sensitivities of 88.4% for RBD, 89.3% for S1, and 72.9% for N protein, the specificity was above 94% for all tests. Out of 54 SARS‐CoV‐2 positive individuals, 96.3% showed full neutralization of live SARS‐CoV‐2 at serum dilutions ≥ 1:16, while none of the 6 SARS‐CoV‐2‐negative sera revealed neutralizing activity.ConclusionsELISAs targeting RBD and S1 protein of SARS‐CoV‐2 are promising immunoassays which shall be further evaluated in studies verifying diagnostic accuracy and protective immunity against SARS‐CoV‐2.
Social Dimensions of Health: Ritual Practice, Moral Orders, and Worlds of Meaning in Brazilian Candomblé and Umbanda Temples
Authors: Markus Wiencke 
Published: September 2020

AbstractIn Western medicine the interpretation prevails that mental illness is a psychological and/or biological disorder. Most important concepts in health psychology, such as sense of coherence, self‐efficacy, hope, or dispositional optimism are all very cognition and individual centered. In this individualized perspective, mental illness is constructed in such a way that it can be treated in a dyadic doctor–patient or therapist–patient relationship with the help of drugs or therapeutic techniques. In this article, I would like to develop a contrasting social construction of mental illness. In Umbanda and Candomblé temples in Brazil, what is interpreted in the Western model as illness is understood as a “spiritual problem.” Here, the individual is constructed in relationship to the community, and individual health and healing is footed in moral‐spiritual orders. In presenting the details of my investigation, I will apply Grawe’s common factors as a foil for developing the link between mental illness and its social context.
Ocular complications of oak processionary caterpillar setae in the Netherlands; case series, literature overview, national survey and treatment advice
Authors: Tan Matthew K. H. , Jalink Maarten B. , Sint Jago Naïlah F. M. , Ho Lintje , Arnold van Vliet J. H. , Das Tridib , de Faber Jan Tjeerd H. N. , Wisse Robert P. L. 
Published: September 2020

AbstractDuring early summer 2019, the Netherlands experienced an outbreak of the exotic oak processionary caterpillar. The vast number of caterpillars, which live in large nests on oak trees before they turn into moths, possess thousands of small, barbed hairs (setae) that are disseminated with the wind. The hairs cause a range of primarily dermatologic problems. However, Dutch ophthalmologists started reporting patients with ophthalmologic complaints caused by the penetrating hairs of the oak processionary caterpillar. This paper focuses on the ophthalmologic complications caused by the caterpillar hairs. We collected a series of four cases with reports ranging from a corneal erosion with hairs lodged into the cornea, to a sterile endophthalmitis in which hairs were found in the vitreous. A literature review for similar cases was performed using the PubMed and Embase database. Together with the Dutch Ophthalmic Society (Nederlands Oogheelkundig Gezelschap, NOG), a national survey was issued to determine the scale of this new problem. This showed that oak processionary caterpillar related complaints are primarily limited to the south of the Netherlands. Suggested ophthalmic treatment guidelines are presented. With the next summer at the doorstep, and limited preventative measures against the caterpillar hairs, we expect a new wave of ophthalmologic complaints coming year as well.
Fitness‐associated substitutions following failure of direct‐acting antivirals assessed by deep sequencing of full‐length hepatitis C virus genomes
Authors: Fourati Slim , Rodriguez Christophe , Soulier Alexandre , Donati Flora , Hamadat Sabah , Poiteau Lila , Demontant Vanessa , Brillet Rozenn , Ahnou Nazim , Gricourt Guillaume , Chevaliez Stéphane , Ahmed‐Belkacem Abdelhakim , Pawlotsky Jean‐Michel 
Published: September 2020

SummaryBackgroundIn hepatitis C virus (HCV) infection, treatment failure is generally associated with the selection of resistance‐associated substitutions (RAS) conferring reduced susceptibility to direct‐acting antiviral (DAA) drugs. Resistant variants continue to replicate after the end of treatment with potential for transmission. This may result from the selection of “fitness‐associated substitutions”.AimTo characterise potential “fitness‐associated substitutions” in patients infected with genotype 3a failing DAA drugsMethodsBy means of shotgun metagenomics, we sequenced full‐length HCV genomes at treatment initiation and at virological relapse in eight patients infected with genotype 3a with cirrhosis failing sofosbuvir and an NS5A inhibitor. The impact of amino acid changes occurring outside of DAA target regions selected in at least two patients were assessed on the in vitro susceptibility to an NS5A inhibitor and replication capacity.ResultsAt treatment failure, besides selection of known NS5A RASs, especially Y93H, a large number of amino acid changes was observed outside of DAA target regions. We identified four amino acid positions at which observed changes substantially improved in vitro replication capacity without affecting NS5A inhibitor susceptibility.ConclusionsThis is the first in vivo observation combined with in vitro confirmation of selection of phenotypically characterised “fitness‐associated substitutions” together with RASs at the time of sofosbuvir‐NS5A inhibitor treatment failure in patients infected with genotype 3a with cirrhosis. Our findings may explain the persistence of resistant HCV variants after treatment in patients who did not achieve sustained virological remission.
Does the time from symptom onset to surgery affect the outcomes of patients with acute appendicitis? A prospective cohort study of 255 patients
Authors: Jiang Li , Liu Zhonghui , Tong Xiaojun , Deng Yang , Liu Jianwen , Yang Xuefei , Chan Fion S.Y. , Fan Joe K.M. 
Published: September 2020

AbstractIntroductionThe objective of this study was to evaluate the impact of operative timing on outcomes of acute appendicitis.MethodsThis study examined adult patients who had presented to the hospital with acute appendicitis and had undergone appendectomy from December 2017 to February 2019. Time delay and outcomes of perforated and non‐perforated appendicitis were compared. Patients were classified into five groups based on the period from symptom onset to operation: group 1, <24 hours; group 2, ≥24 and <48 hours; group 3, ≥48 and <72 hours; group 4, ≥72 and <96 hours; and group 5, ≥96 hours. The five groups were compared, with risk of perforation assessed in particular.ResultsA total of 255 patients were included in the analysis. Symptom duration, operative time, and length of postoperative hospital stay (P < .001) were significantly longer in the perforated group (n = 49) than in the non‐perforated group (n = 206). The perforated group also had a higher conversion rate to open procedures (P = .002) and a higher rate of wound infection (P = .034). Group 1 had 53 patients, group 2 had 95 patients, group 3 had 57 patients, group 4 had 32 patients, and group 5 had 18 patients. The incidence of appendiceal perforation and median operative time progressively increased along with symptom duration in the five groups. In multivariate analyses, independent risk factors for appendiceal perforation were male gender (odds ratio = 2.33, 95% confidence interval [CI]: 1.07‐5.08) and symptom duration ≥48 hours (relative to ≥24 and <48 hours) (odds ratio = 4.64, 95%CI: 1.76‐12.27). Patients with symptom duration ≥72 hours had a significantly longer operative time than those with symptom duration ≥48 and <72 hours (β = 21.38, 95%CI: 5.66‐37.11, P = .008).ConclusionThe risk of perforation increased significantly 48 hours after the onset of appendicitis. Symptoms duration ≥72 hours was associated with a longer operative time.