bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparison of the quality of image acquisition between two different sidestream dark field video-microscopes
Authors: Coppel Jonny , Bountziouka Vassiliki , Martin Daniel , Gilbert-Kawai Edward 
Published: May 2020

AbstractSidestream dark field (SDF) imaging enables direct visualisation of the microvasculature from which quantification of key variables is possible. The new MicroScan USB3 (MS-U) video-microscope is a hand-held SDF device that has undergone significant technical upgrades from its predecessor, the MicroScan Analogue (MS-A). The MS-U claims superior quality of sublingual microcirculatory image acquisition over the MS-A, however, this has yet to be robustly confirmed. In this manuscript, we therefore compare the quality of image acquisition between these two devices. The microcirculation of healthy volunteers was visualised to generate thirty video images for each device. Two independent raters, blinded to the device type, graded the quality of the images according to the six different traits in the Microcirculation Image Quality Score (MIQS) system. Chi-squared tests and Kappa statistics were used to compare not only the distribution of scores between the devices, but also agreement between raters. MS-U showed superior image quality over MS-A in three of out six MIQS traits; MS-U had significantly more optimal images by illumination (MS-U 95% optimal images, MS-A 70% optimal images (p-value 0.003)), by focus (MS-U 70% optimal images, MS-A 35% optimal images (p-value 0.002)) and by pressure (MS-U 72.5% optimal images, MS-A 47.5% optimal images (p-value 0.02)). For each trait, there was at least 85% agreement between the raters, and all the scores for each trait were independent of the rater (all p-values > 0.05). These results show that the new MS-U provides a superior quality of sublingual microcirculatory image acquisition when compared to old MS-A
Interaction between endophytic Proteobacteria strains and Serendipita indica enhances biocontrol activity against fungal pathogens
Authors: del Barrio-Duque Alejandro , Samad Abdul , Nybroe Ole , Antonielli Livio , Sessitsch Angela , Compant Stéphane 
Published: May 2020

AbstractAimsPlants host communities of fungal and bacterial endophytes, establishing a complex network of multipartite interactions, but the mechanisms whereby they interact are poorly understood. Some fungi, such as the beneficial mycorrhiza-like fungusSerendipita(=Piriformospora)indica, can be helped by bacteria for establishment, survival and colonization. Although this fungus harbors aRhizobiumas an endofungal bacterium, we hypothesized that other bacteria might also establish associations with the fungus and combiningS. indicawith bacteria might enhance plant growth and health.MethodsThe interactions amongS. indicaand four endophytic Proteobacteria belonging toMethylobacterium,Tardiphaga,RhodanobacterandTrinickiaspp. were characterized in vitro and for their effect on tomato growth and biocontrol ofFusarium oxysporumandRhizoctonia solani. Possible mechanisms behind these interactions were described based on genome and microscopic analyses, using fungal and bacterial strains tagged with fluorescent markers.ResultsAll bacteria stimulatedS. indicagrowth in vitro. Moreover, several of the bacteria stimulated growth of tomato plants, but co-inoculations withS. indicaand bacteria did not perform better than single inoculations. Contrarily, combinations ofS. indicaand bacteria significantly reduced disease progression of fungal pathogens. These microbes seem to cooperate in the process of root colonization for instance by increasing fungal sporulation and hyphae expansion, showing multipartite interaction between microbes and plants. Interestingly, the strain ofTrinickiainternally colonizes spores ofS. indicaas an endofungal bacterium during in vitro-co-culturing, suggesting further that the fungus might acquire formerly unrecognized genera of bacteria and genome analysis of the bacteria revealed many genes potentially involved in fungal and plant growth stimulation, biocontrol and root colonization, highlighting putative mechanisms of plant-fungal-bacterial interaction.ConclusionsOur study represents an important step towards unraveling the complex interactions among plants,S. indica, endophytic bacteria and fungal pathogens, and indicates that adding bacteria to fungal inoculum could have a remarkable impact on the plant-S. indicasymbiosis.
How does monitoring set the stage for adaptive regulation or maladaptive behavior in collaborative learning?
Authors: Sobocinski Márta , Järvelä Sanna , Malmberg Jonna , Dindar Muhterem , Isosalo Antti , Noponen Kai 
Published: May 2020

AbstractIn collaborative learning situations, monitoring is needed to maintain common progress toward shared goals. The present study aimed to analyze group-level monitoring events, as well as groups’ reactions to these events, to identify instances of adaptive regulation and maladaptive behavior. Three dimensions of monitoring events were qualitatively coded from video data: the monitoring target, valence, and phase, which provided insight into identifying critical moments during the collaborative process when regulation is needed. By looking at what kind of monitoring the groups engaged in, and how the groups progressed after the need for regulation arose, different types of adaptive regulation and maladaptive behavior were distinguished. In addition, group-level physiological state transitions in the heart rate were explored to see whether changes in regulation (adaptive regulation and maladaptive behavior) were reflected in the state transitions. Nine groups of three students each participated in a collaborative exam for an advanced high school physics course, during which video and heart rate data were collected. The results showed that on-track sequences were the most common, followed by adaptive sequences. The temporality of these sequences was examined, and four categories of group progress are described with case examples. A correlation analysis showed that physiological state transitions were positively correlated with on-track sequences. The opportunities and limitations of using three dimensions of monitoring and heart-rate based physiological state transitions to study adaptive regulation are discussed.
Deep learning-based anatomical site classification for upper gastrointestinal endoscopy
Authors: He Qi , Bano Sophia , Ahmad Omer F. , Yang Bo , Chen Xin , Valdastri Pietro , Lovat Laurence B. , Stoyanov Danail , Zuo Siyang 
Published: May 2020

Abstract
Purpose
Upper gastrointestinal (GI) endoscopic image documentation has provided an efficient, low-cost solution to address quality control for endoscopic reporting. The problem is, however, challenging for computer-assisted techniques, because different sites have similar appearances. Additionally, across different patients, site appearance variation may be large and inconsistent. Therefore, according to the British and modified Japanese guidelines, we propose a set of oesophagogastroduodenoscopy (EGD) images to be routinely captured and evaluate its efficiency for deep learning-based classification methods.

Methods
A novel EGD image dataset standardising upper GI endoscopy to several steps is established following landmarks proposed in guidelines and annotated by an expert clinician. To demonstrate the discrimination of proposed landmarks that enable the generation of an automated endoscopic report, we train several deep learning-based classification models utilising the well-annotated images.

Results
We report results for a clinical dataset composed of 211 patients (comprising a total of 3704 EGD images) acquired during routine upper GI endoscopic examinations. We find close agreement between predicted labels using our method and the ground truth labelled by human experts. We observe the limitation of current static image classification scheme for EGD image classification.

Conclusion
Our study presents a framework for developing automated EGD reports using deep learning. We demonstrate that our method is feasible to address EGD image classification and can lead towards improved performance and additionally qualitatively demonstrate its performance on our dataset.
Self-set salaries and creativity
Authors: Brück Christian , Knauer Thorsten , Meier Harald , Schwering Anja 
Published: May 2020

AbstractOrganizations frequently try to incentivize employees to develop highly creative solutions. In this study, we examine self-set salaries as a specific type of incentive design. We investigate whether self-set salaries affect employees’ motivation and overall (creative) performance. Moreover, because self-set salaries potentially risk opportunistic employee behavior, we consider the effect of the observability of peer performance on employees’ level of self-set salaries. Using a laboratory experiment, we hold the average employee compensation constant and demonstrate that, in comparison with fixed-pay contracts, self-set salaries increase the quantitative performance in creative tasks without affecting the average creativity. However, we do not find significant differences between the amount of individuals’ self-set salaries with observability of peer performance and the amount for individuals without the chance to observe peer performance. Our findings are important for firms that rely on the development of creative ideas but are unsure about the effects of the introduction of self-set salaries.
A surrogate FRAX model for the Kyrgyz Republic
Authors: Lesnyak O. , Zakroyeva A. , Lobanchenko O. , Johansson H. , Liu E. , Lorentzon M. , Harvey N. C. , McCloskey E. , Kanis J. A. 
Published: May 2020

Abstract

Summary

The hip fracture rates from Kazakhstan were used to create a surrogate FRAX® model for the Kyrgyz Republic.

Introduction
The International Society for Clinical Densitometry and International Osteoporosis Foundation recommend utilizing a surrogate FRAX model, based on the country-specific risk of death, and fracture data based on a country where fracture rates are considered to be representative of the index country.

Objective
This paper describes a surrogate FRAX model for the Kyrgyz Republic.

Methods
The FRAX model used the incidence of hip fracture from the neighbouring country of Kazakhstan and the death risk for the Kyrgyz Republic.

Results
Compared with the model for Kazakhstan, the surrogate model gave somewhat higher 10-year fracture probabilities for men between 60 and 80 years of age and lower probabilities for men above the age of 80. For women the probabilities were similar up to the age of 75–80 years and then lower. There were very close correlations in fracture probabilities between the surrogate and authentic models (1.00) so that the use of the Kyrgyz model had little impact on the rank order of risk. It was estimated that 2752 hip fractures arose in 2015 in individuals over the age of 50 years in the Kyrgyz Republic, with a predicted increase by 207% to 8435 in 2050.

Conclusion
The surrogate FRAX model for the Kyrgyz Republic provides the opportunity to determine fracture probability among the Kyrgyz population and help guide decisions about treatment.
The Effectiveness of Grain Refinement by Machine Hammer Peening in High Deposition Rate Wire-Arc AM Ti-6Al-4V
Authors: Hönnige J. R. , Davis A. E. , Ho A. , Kennedy J. R. , Neto L. , Prangnell P. , Williams S. 
Published: May 2020

Abstract
Surface deformation, applied in-process by machine hammer peening (MHP), has the potential to refine the coarse columnar β-grain structures normally found in high deposition rate Wire-Arc Additive Manufacturing (WAAM) processes with Ti alloys like Ti-6Al-4V. Effective refinement, as well as a reduction in texture strength, has been achieved in relatively thick sections and to a depth that is greater than that expected from the surface deformation induced by MHP. By application of MHP to each deposition track, the average β-grain size could be reduced from cm’s to less than 0.5 mm. Systematic experiments have been performed to investigate the origin of this interesting effect, which included ‘stop-action’ trials and separation of the strain and temperature gradients induced by the two process steps. The maximum depth of the plastic deformation from MHP required to generate new β-grain orientations was determined by electron backscatter diffraction local average misorientation analysis to be < 0.5 mm, which was less than the melt pool depth in the WAAM process. Nevertheless, new β-grain orientations were observed to form within the peened layer ahead of the approaching heat source as the peak temperature rose above the β transus, which then grew into the less deformed core of the wall as the temperature rose. This allowed the new grain orientations to penetrate deeper than the melt pool depth and survive to act as substrates for epitaxial growth at the fusion boundary during solidification, resulting in significant grain refinement.
Return to Play After a Lateral Ligament Ankle Sprain
Authors: D’Hooghe P. , Cruz F. , Alkhelaifi K. 
Published: May 2020

Abstract
Purpose of Review
The purpose of this review is to describe the current evidence on the most common sports-related ankle injuries. Joint anatomy, epidemiology, clinical findings, diagnostic approach, and treatment are presented with a specific focus on the available evidence towards return to play.

Recent Findings
Recent findings show that ankle sprain is the most common injury in the world of sports. Bony fractures, cartilage defects, and syndesmotic lesions are frequently seen in association with the more severe type of ankle sprains.

Summary
In summary, the majority of the athletes’ ankle sprains are managed conservatively with excellent outcomes and full return to their pre-injury level of play. However, it is essential to differentiate the single ligament sprain from a more complex injury to the ankle joint. The evidence-based treatment and rehabilitation programmes are associated with a better prognosis and a faster time to return to sport participation.
Phosphodiesterase 10A Inhibition Leads to Brain Region-Specific Recovery Based on Stroke Type
Authors: Birjandi Shirin Z. , Abduljawad Nora , Nair Shyama , Dehghani Morteza , Suzuki Kazunori , Kimura Haruhide , Carmichael S. Thomas 
Published: May 2020

AbstractStroke is the leading cause of adult disability. Recovery of function after stroke involves signaling events that are mediated by cAMP and cGMP pathways, such as axonal sprouting, neurogenesis, and synaptic plasticity. cAMP and cGMP are degraded by phosphodiesterases (PDEs), which are differentially expressed in brain regions. PDE10A is highly expressed in the basal ganglia/striatum. We tested a novel PDE10A inhibitor (TAK-063) for its effects on functional recovery. Stroke was produced in mice in the cortex or the striatum. Behavioral recovery was measured to 9 weeks. Tissue outcome measures included analysis of growth factor levels, angiogenesis, neurogenesis, gliogenesis, and inflammation. TAK-063 improved motor recovery after striatal stroke in a dose-related manner, but not in cortical stroke. Recovery of motor function correlated with increases in striatal brain-derived neurotrophic factor. TAK-063 treatment also increased motor system axonal connections. Stroke affects distinct brain regions, with each comprising different cellular and molecular elements. Inhibition of PDE10A improved recovery of function after striatal but not cortical stroke, consistent with its brain localization. This experiment is the first demonstration of brain region-specific enhanced functional recovery after stroke, and indicates that differential molecular signaling between brain regions can be exploited to improve recovery based on stroke subtype.
Cucurbitane-Type Triterpene Glycosides from Momordica charantia and Their α-Glucosidase Inhibitory Activities
Authors: Gao Ya , Chen Jian-Chao , Peng Xing-Rong , Li Zhong-Rong , Su Hai-Guo , Qiu Ming-Hua 
Published: May 2020

Abstract
Ten cucurbitane-type triterpene glycosides, including five new compounds named charantosides H (1), J (2), K (3), momorcharacoside A (4), goyaglycoside-l (5), and five known compounds (6–10), were isolated from the EtOAc extract of Momordica charantia fruits. The chemical structures of these compounds were identified by 1D and 2D NMR and HRESIMS spectroscopic analyses. Configurations of new compounds were determined by ROESY correlations and comparison of their 13C NMR data with literature reported values. All compounds were evaluated for their inhibition against α-glucosidase, in which compounds 2, 5, 7, 8, 9 showed moderate inhibitory activities with IC50 values ranging from 28.40 to 63.26 μM comparing with the positive control (acarbose, IC50 87.65 ± 6.51 μM).

Graphic Abstract
A force levels and gestures integrated multi-task strategy for neural decoding
Authors: Hua Shaoyang , Wang Congqing , Xie Zuoshu , Wu Xuewei 
Published: May 2020

AbstractThis paper discusses the problem of decoding gestures represented by surface electromyography (sEMG) signals in the presence of variable force levels. It is an attempt that multi-task learning (MTL) is proposed to recognize gestures and force levels synchronously. First, methods of gesture recognition with different force levels are investigated. Then, MTL framework is presented to improve the gesture recognition performance and give information about force levels. Last but not least, to solve the problem that using the greedy principle in MTL, a modified pseudo-task augmentation (PTA) trajectory is introduced. Experiments conducted on two representative datasets demonstrate that compared with other methods, frequency domain information with convolutional neural network (CNN) is more suitable for gesture recognition with variable force levels. Besides, the feasibility of extracting features that are closely related to both gestures and force levels is verified via MTL. By influencing learning dynamics, the proposed PTA method can improve the results of all tasks, and make it applicable to the case where the main tasks and auxiliary tasks are clear.
The Principle of Introducing Halogen Ions Into β-FeOOH: Controlling Electronic Structure and Electrochemical Performance
Authors: Zhang Dongbin , Han Xuzhao , Kong Xianggui , Zhang Fazhi , Lei Xiaodong 
Published: May 2020

AbstractCoordination tuning electronic structure of host materials is a quite effective strategy for activating and improving the intrinsic properties. Herein, halogen anion (X−)-incorporated β-FeOOH (β-FeOOH(X), X = F−, Cl−, and Br−) was investigated with a spontaneous adsorption process, which realized a great improvement of supercapacitor performances by adjusting the coordination geometry. Experiments coupled with theoretical calculations demonstrated that the change of Fe–O bond length and structural distortion of β-FeOOH, which is rooted in halogen ions embedment, led to the relatively narrow band gap. Because of the strong electronegativity of X−, the Fe element in β-FeOOH(X)s presented the unexpected high valence state (3 + δ), which is facilitating to adsorb SO32− species. Consequently, the designed β-FeOOH(X)s exhibited the good electric conductivity and enhanced the contact between electrode and electrolyte. When used as a negative electrode, the β-FeOOH(F) showed the excellent specific capacity of 391.9 F g−1 at 1 A g−1 current density, almost tenfold improvement compared with initial β-FeOOH, with the superior rate capacity and cyclic stability. This combinational design principle of electronic structure and electrochemical performances provides a promising way to develop advanced electrode materials for supercapacitor.
Negative views of Islam in Switzerland with special regard to religiosity as an explanatory factor
Authors: Yendell Alexander , Huber Stefan 
Published: May 2020

AbstractDrawing on such theoretical paradigms as Social Identity Theory, the deprivation hypothesis, and the concept of trust, we sought to investigate how religiosity relates to attitudes towards Islam among the Swiss population. In this quantitative study based on the data of the Swiss Household Panel 2015 (n=10,848) we took into account both public religious practice and personal religiosity. A hierarchical linear regression analysis revealed that religiosity influenced attitudes towards Islam, in that affiliation to one of the large churches (Protestant or Catholic), had a weak positive influence, which might in turn reflect a focus within the large churches on religious freedom and inter-religious dialogue. The effect of church attendance in general on attitudes was positive albeit rather weak. In comparison, personal religiosity was important, with people with a high level of personal religiosity being more likely to have a positive attitude towards Islam. One important finding was that religiosity contributed more to explaining variance than did other factors such as social trust, political position or national identity. Other influential factors included political attitude and trust in other people. The study also revealed that those Swiss people for whom national identity was particularly important were more likely to have a negative view of Islam. While belonging to an Evangelical denomination was significant in our regression models, and exerted an even stronger negative impact when variables of religiosity were included, the impact lost its significance in models which included the importance of Swiss identity. We conclude that Evangelicals are more negative towards Islam not because of their religiosity, but because they tend to have a strong national identity.
Caring or Not Caring for Coworkers? An Empirical Exploration of the Dilemma of Care Allocation in the Workplace
Authors: Antoni Anne , Reinecke Juliane , Fotaki Marianna 
Published: May 2020

ABSTRACTOrganization and management researchers praise the value of care in the workplace. However, they overlook the conflict between caring for work and for coworkers, which resonates with the dilemma of care allocation highlighted by ethicists of care. Through an in-depth qualitative study of two organizations, we examine how this dilemma is confronted in everyday organizational life. We draw on the concept of boundary work to explain how employees negotiate the boundary of their caring responsibilities in ways that grants or denies care to coworkers. We argue that the possibility of an ethics of care for coworkers requires boundary work that suspends the separation of personal and professional selves and constitutes the worker as a whole person. We contribute to research on care in organizations by showing how care for coworkers may be enabled or undermined by maintaining or suppressing the care allocation dilemma.
Interpersonal violence and mental health: a social justice framework to advance research and practice
Authors: Tol W.A. 
Published: May 2020

Abstract
This editorial paper accompanies a special series in the journal Global Mental Health focused on the topic of interpersonal violence and mental health. This series included 24 papers reporting on data from 31 countries, published between 2017 and 2019. This accompanying paper provides a short summary of findings in the special series and reflects on next steps in research and practice. Collectively, the series’ 24 papers suggest intricate bi-directional relationships between interpersonal violence and mental health, situated in particular contexts and varying across the life course. In order to study this complexity, an overarching theoretical framework is critical. This paper takes the social justice theory developed by Powers and Faden (2006, 2019) as a starting point. It is argued that application of this social justice framework will be helpful to: strengthen conceptual clarity; provide a sense of direction for research and practice in the area of interpersonal violence and mental health; assist in conducting more fine grained analyses of contextually determined processes of disadvantage; and help situate disciplinary specific research and practice questions in their broader context, thereby strengthening multi-disciplinary research and multi-sectoral policy and programming efforts.