bluuebunny/crossref_metadata_2025_split huggingface dataset:
Re‐Investigating the UIP Hypothesis: Recent Evidence From BRICS Economies
Authors: Bhatia Madhur 
Published: December 2024

ABSTRACTThe study re‐investigates the existence of the Uncovered interest parity (UIP) hypothesis and substantially adds to the literature by offering the most recent evidence during the period from 2000 to 2022 from developing and emerging economies. The study further augments the literature by extending the standard UIP hypothesis to account for the monetary policy stance and risk premium. The estimates of nonlinear autoregressive distributed lag (NARDL) and component generalised autoregressive conditional heteroscedasticity (C‐GARCH) show that the UIP hypothesis does not exist in any of the BRICS economies. Nevertheless, after accounting for the risk premium and monetary policy stance using inflation levels, the interest rate differential significantly and positively influences the expected changes in the spot exchange rates. This indicates three important aspects: first, the necessity of risk premium to make up for the higher risk that comes with holding the foreign bond for the benefit of domestic investors. Second that the UIP puzzle does not hold, such that higher interest differential depreciates the domestic currency. Third, the analysis underscores the substantial and direct impact of US inflation level, particularly for Brazil, Russia and India, in determining the changes in the spot exchange rate. These insights hold crucial implications for policymakers and regulators.
Tip efficiency of a customized lingual appliance: Performance of wires with two different ligatures
Authors: Drago Sara , Lagazzo Alberto , De Mari Anna , Rizzi Luigi , Stradi Roberto , Menini Maria , Migliorati Marco 
Published: December 2024

AbstractTip control in lingual orthodontics may be challenging because of the presence of a vertical slot and the particular configuration of the customized appliances. The aim of this in vitro experimental study was to investigate the role of the ligature–wire–slot system in achieving better tip control. A set of customized lingual brackets was obtained for a dedicated typodont made of extracted human teeth. A compression/traction machine tested two types of ligatures in combination with seven different wires, and the tipping angle of each configuration was derived. A statistically significant difference was found between ligatures when the complete set of data was tested. In addition, differences between ligatures were found when testing each wire separately. A statistically significant difference was found among all wires. Full‐size wires showed the smallest angles, which correspond to the greatest efficiency of the slot–archwire–ligation system in terms of tip control, and this efficiency appeared to be ligature‐related. The role played by the type of ligature was more relevant for undersized wires.
Clinical and Biochemical Efficacies of Green and White Tea Extract Mouthwashes in the Management of Plaque‐Induced Gingivitis
Authors: Kose Oguz , Sarac Gul Yagmur , Altin Ahmet , Bostan Semih Alperen , Faiz Ozlem , Akyildiz Kerimali , Yilmaz Adnan 
Published: December 2024

ABSTRACTObjectiveIn this clinical study, chlorhexidine gluconate (CHX) was chosen as the positive control group, and the clinical and biochemical efficacy of mouthwashes with green tea, white tea and essential oil (EO) as the active ingredients were aimed to be examined comprehensively.MethodsA total of 112 participants with gingivitis were randomly assigned to four different groups and different mouthwashes were used for 4 weeks: CHX‐MW group (as a positive control group), EO‐MW group, GT‐MW group and WT‐MW group. The effects of the mouthwashes on plaque, inflammation and dental staining were evaluated by indexed scores at the beginning and 4th week. Markers related to gingival inflammation and oxidative stress were evaluated on samples from the gingival crevicular fluid.ResultsIn the 4th week, significant improvements in clinical parameters were found in all groups (p < 0.05) with the more pronounced improvement in the CHX‐MW group (p < 0.05). However, only the CHX caused a significant discolouration of both teeth and tongue (p < 0.05). The levels of IL‐1β and MMP‐8 were found to be lower in all groups compared to the first measurements (p < 0.05). Furthermore, the antioxidant effect of EO mouthwash was found significantly low compared to the other three mouthwashes (p < 0.05).ConclusionGreen and white tea extracts provided clinical benefits in the short term (1 month) with no statistical difference from each other and mouthwash with EO as the active ingredient while they provided a lower clinical benefit compared to CHX. Products with tea as the active ingredient may be an alternative to EO mouthwash for short‐term and long‐term use.
The Predictive Effects of L2 Writing Anxiety on Motivational Regulation Strategies: A Person‐Centered Approach
Authors: Huang Zhenlei , Hu Xinjian , Jin Hui 
Published: December 2024

ABSTRACTUsing a person‐centered approach, the present study aimed to investigate the potential profiles of motivational regulation strategies for writing (MRSW) and examine the predictive effect of L2 writing anxiety on the membership of MRSW profiles. Data were collected from a sample of 604 secondary school students with two questionnaires. The Second Language Writing Strategies for Motivational Regulation Questionnaire (L2WSMRQ) was employed to identify the possible MRSW profiles, and the Second Language Writing Anxiety Inventory (SLWAI) was administered to reveal the association between these profiles and L2 writing anxiety among this population. Three distinct profiles (i.e., low, medium, and high MRSW profile) were identified via latent profile analysis. Multinomial logistic regression revealed that cognitive anxiety and avoidance behavior served as effective predictors of the membership of MRSW profiles. These findings may shed light on the heterogeneous configuration patterns of strategy use in EFL writing and provide practical implications for practitioners and researchers aiming to offer personalized instructions tailored to different profiles and anxiety levels.
Satisfaction with social care in the UK: Assessing the interactive effects of age and ideology
Authors: Kevins Anthony , Lightman Naomi 
Published: December 2024

AbstractSocial care is a pressing policy issue in the UK, where it is widely acknowledged that the status quo—including who pays, profits, and receives/delivers care—is unsustainable. Yet we know relatively little about the factors shaping satisfaction with the current system, as most prior research has been either descriptive in nature or focused on assessing funding priorities. This study investigates determinants of social care satisfaction for the UK general population, paying particular attention to the potentially interactive effect of age and ideology. Using 2012–2019 BSA Survey data, we find that middle‐aged respondents are particularly dissatisfied with social care, but that ideology complicates this dynamic: while conservatives were broadly more satisfied with social care than progressives, this ideology effect disappears among older respondents. This result is largely driven by a modest increase in satisfaction among older progressives—though satisfaction remains low even among comparatively more satisfied groups.
Rationales for service user participation in social care: A regulatory perspective
Authors: Dolev Hilla , Benish Avishai 
Published: December 2024

AbstractThis study examined the regulator's perspective on service user participation in social care. To date, empirical research has focused on the participatory methods themselves rather than on regulators' motivations for using them. Drawing on case studies of social care regulators in England (Care Quality Commission), Australia (Aged Care Quality and Safety Commission), and Sweden (Health and Social Care Inspectorate), we identified three distinct rationales for promoting service user participation: gaining public trust and legitimacy, improving regulatory processes, and empowering service users. Each rationale embeds different underlying assumptions about the contribution of service users to the regulatory process and the regulator's role to promote it. Furthermore, these distinct assumptions are associated with participatory methods that reflect different participatory approaches: democratic or consumerist, collective, or individual.
Job demands‐control, job support, and depressive symptoms: Unraveling job support's moderating mechanism among social workers in China
Authors: Ge Ting , Lu Xiaoqiong , He Guangye , Ren Yiqi , Ji Feng 
Published: December 2024

AbstractWork‐induced stress poses significant mental health risks in high‐stress professions, such as social workers. This study, grounded in the Job Demands‐Control‐Support model and Conservation of Resources theory, explores how job stressors affect social workers' depressive symptoms, focusing on job demands, job control, and their combinations, alongside the moderating role of job support. Analyzing data from the 2019 China Social Work Longitudinal Study through a city‐level fixed‐effects model, we find that job demands (role ambiguity and role conflict) and job control influence depressive symptoms both independently and interactively. Specifically, high job demands increase depressive symptoms, while greater job control reduces them. When looking at the combination of job demands and control, social workers facing low job demands with high job control report the lowest levels of depressive symptoms, followed by those with low demands and low job control. Moreover, coworker support emerges as crucial in reducing depression, especially for those grappling with high‐role ambiguity and job control. Additionally, in high role conflict with low job control scenarios, support from leaders and supervisors is essential for lessening depressive symptoms. These findings highlight the essential role of job support in mitigating the impact of job stressors on social workers' mental health in China.
Loss of acid suppression during dosing with H2‐receptor antagonists
Authors: Wilder‐Smith C. , Halter F. , Ernst T. , Gennoni M. , Zeyen B. , Varga L. , Roehmel J. J. , Merki H. S. 
Published: December 2024

SUMMARYThe suppression of intragastric acidity with H2‐receptor antagonists may diminish with repeated administration. To assess the degree and dose‐dependance of this tolerance after short‐term dosing, two doses of the H2‐receptor antagonists, ranitidine (300 mg node or q.d.s.) and sufotidine (300 mg or 600 mg b.d.), were given to healthy volunteers for 1 and 2 weeks, respectively. After 1 and 7 days of dosing with ranitidine 300 mg q.d.s. the median 24‐h and night‐time pH, measured by continuous 24‐h pH‐metry, dropped from 3.7 to 2.2 and 5.8 to 3.2, respectively (P < 0.0001 for both). The decline in median pH with ranitidine 300 mg node was only significant during the night (from 4.1 to 2.9) (P < 0.04). There was little change in plasma gastrin concentrations between days 1 and 7 with either dosage. With sufotidine 300 mg b.d. and 600 mg b.d. for 1 and 14 days, the median 24‐h pH fell from 3.7 to 2.1 and from 4.6 to 2.6, respectively (P < 0.0001). The equivalent medians for the night decreased‐from 6.3 to 2.3 and from 6.6 to 3.1 (P < 0.0001). Gastrin concentrations did not change after 14 days of dosing with sufotidine 300 mg b.d., but increased significantly during dosing with sufotidine 600 mg b.d. (P < 0.001).Significant tolerance developed in 7‐14 days and it seemed to show some dose relationship. The mechanisms behind tolerance and the role of gastrin are discussed, but remain unclear.
Tolerance during 8 days of high‐dose H2‐blockade: placebo‐controlled studies of 24‐hour acidity and gastrin
Authors: Smith J. T. L. , Gavey C. , Nwokolo C. U. , Pounder R. E. 
Published: December 2024

SUMMARYSimultaneous 24‐h intragastric and plasma gastrin concentrations were measured in 36 healthy subjects, when receiving placebo (day 0) and on days 1 and 8 of dosing with either placebo (n = 8), or high‐dose H2‐blockade with either ranitidine 300 mg q.d.s. (n = 8), ranitidine 1200 mg o.m. (n = 8), or sufotidine 600 mg b.d. (n = 12).Triplicate placebo studies demonstrated good reproducibility for this technique, with no significant differences of acidity or plasma gastrin concentration between the studies.There was a decrease in the anti‐secretory activity of all three high‐dose H2‐antagonist regimens on day 8, when compared with that observed on day 1. This occurred in the presence of sustained or increasing hypergastrinaemia.It is concluded that a degree of tolerance develops during‐continued H2‐blockade, and that this could be due to increasing gastrin drive to the parietal cells.
Dynamic and thermodynamic behavior of supercooled Na–Ba metaphosphate liquids: Role of modifier cation ordering
Authors: Chuang Shih‐Yi , Yu Ping , Sen Sabyasachi 
Published: December 2024

AbstractThe Q‐speciation and the role of modifier dynamics on network relaxation in the supercooled mixed‐alkali–alkaline‐earth (MAAE) Na–Ba metaphosphate liquids are investigated using a combination of 31P nuclear magnetic resonance (NMR) spectroscopy, calorimetric, electrical conductivity, and rheological measurements. Progressive replacement of Na with Ba in these glasses is shown to result in an increasing disproportionation of Q2 species via the reaction: 2Q2 = Q1 + Q3. Unlike mixed‐alkali liquids, the Na–Ba metaphosphate liquids display a monotonic variation in isothermal electrical conductivity, glass transition temperature, calorimetric and kinetic fragility, and isothermal viscosity. It is hypothesized that this monotonic variation arises from the lack of elastic facilitation of network relaxation via coupled hopping of Na–Ba pairs as these modifier cations are prohibited from mixing randomly due to the differences between their size, mass, charge, and mobility. Isobaric heat capacity measurements provide supporting evidence in favor of a such a nonrandom mixing between the modifier cations in Na–Ba metaphosphate glasses and liquids.
Multielectrode Radiofrequency Balloon Catheter for Paroxysmal Atrial Fibrillation: Results From the Global, Multicenter, STELLAR Study
Authors: Goyal Sandeep K. , Pappone Carlo , Grimaldi Massimo , Lee Sung W. , Mountantonakis Stavros , DeVille J. Brian , Sagi Venkata S. , Jiang Chen‐Yang , Jafri Haseeb , Wimmer Alan P. , Wu Li‐Qun , Dukkipati Srinivas , Rashid Haroon , Calkins Hugh , Mansour Moussa , Roman‐Gonzalez Javier , Natale Andrea , Ciconte Giuseppe , Aryana Arash ,   STELLAR investigators
Published: December 2024

ABSTRACTIntroductionThe safety and efficacy of paroxysmal atrial fibrillation (PAF) ablation with the HELIOSTAR multielectrode radiofrequency (RF) balloon catheter have been demonstrated in European studies; data from elsewhere are lacking. This prospective, multicenter study conducted in the United States, Italy, and China investigated the safety and efficacy of pulmonary vein isolation (PVI) using HELIOSTAR in drug‐refractory symptomatic PAF.MethodsThe primary effectiveness endpoint (PEE) was 12‐month freedom from documented atrial fibrillation/atrial flutter/atrial tachycardia plus freedom from acute procedural failure, nonstudy catheter failure, repeat ablation failure, direct current cardioversion (DCCV), and Class I/III antiarrhythmic drug (AAD) failure. The primary safety endpoint was the occurrence of early‐onset primary adverse events (PAEs). Cerebral magnetic resonance imaging (MRI) and cardiac computed tomography were performed in a patient subset to assess silent cerebral lesions (SCLs) and severe pulmonary vein (PV) stenosis, respectively.ResultsAcross 36 centers, 257 eligible subjects in the main phase had the study catheter inserted. Acute PVI was achieved in all subjects, with the majority (94.1%) using the balloon catheter only. In 67.7% and 92.2% of subjects, respectively, PEE and freedom from repeat ablation were met; clinical success rate was 77.7%. The PAE rate was 5.1%. One of 15 (6.7%) subjects with MRI showed a new SCL at 1 month postablation, which resolved at 3 months. Clinically meaningful improvements in Atrial Fibrillation Effect on QualiTy‐of‐life scores were seen at 3 months and were sustained to 12 months postablation, and accompanied with reduction of Class I/III AAD use and DCCV.ConclusionSTELLAR confirmed the safety and efficacy of the HELIOSTAR catheter for PVI, with clinically meaningful improvements in quality of life in patients with drug‐refractory symptomatic PAF. Most PVIs were achieved without focal touch‐up, and > 90% of patients were free from repeat ablation at 12 months.Trial RegistrationClinicalTrials.gov Identifier: NCT03683030.
The Impact of Socioeconomic Inequalities on the Risk of Hypertension in Bangladesh: A Systematic Review and Meta‐Analysis
Authors: Hossain Kabir , Shuvo Tonmoy Alam , Hosna Asma‐Ul , Dey Dipu Rani 
Published: December 2024

ABSTRACTHypertension is a prevalent health issue in Bangladesh, impacting a significant portion of the population. This meta‐analysis explored how social status inequalities impact hypertension risk in Bangladesh. We systematically searched various electronic databases and rigorously selected 12 studies for inclusion in the analyses. The I2 statistic measured between study heterogeneity, and pooled effect estimates were obtained using the DerSimonian and Laird random effects model to address this variability. Publication bias was assessed through a funnel plot and Egger's test. Sensitivity analysis was conducted to evaluate the robustness of the findings. All analyses were performed using STATA 17. The analyses indicated that females had a significantly higher risk of developing hypertension compared to males, with a pooled odds ratio (OR) of 1.15 (95% confidence interval [CI]: 1.02–1.27). Urban residents showed a pooled OR of 1.11 (95% CI: 1.03–1.19) compared to rural residents. The pooled ORs for hypertension were 1.02 (95% CI: 0.89–1.14) for primary education, 1.07 (95% CI: 0.94–1.21) for secondary education, and 1.25 (95% CI: 1.03–1.47) for higher secondary education, suggesting an increasing risk with higher education levels. Wealth status showed a pooled OR of 1.08 (95% CI: 0.87–1.29) for the poorer class, 1.13 (95% CI: 1.04–1.22) for the middle class, 1.38 (95% CI: 0.68–2.07) for the richer class, and 1.49 (95% CI: 0.97–2.00) for the richest class, indicating a greater risk of hypertension among wealthier individuals. Working individuals had a 39% lower risk of hypertension (OR = 0.61, 95% CI: 0.43–0.80) compared to nonworking individuals.
PDIA3 rs2788: An Independent Risk Factor for Hypertension and Its Interaction With Antihypertensive Medications
Authors: Lan Hongtao , Xi Yingbin , Kang Baoxu , Tong Zhoujie , Peng Jie , Zhang Wei , Zhong Ming , Gong Huiping , Wang Zhihao 
Published: December 2024

ABSTRACTHypertension is a multifactorial condition influenced by both genetic and environmental factors. Protein disulfide isomerase family A member 3 (PDIA3) is a key endoplasmic reticulum protein which may contribute to increased blood pressure. However, the relationship between PDIA3 polymorphisms and hypertension remain unclear. This study aims to explore the relationship between PDIA3 polymorphisms and hypertension. First, Mendelian randomization (MR) analyses were performed to assess the causal link between PDIA3 and hypertension. Second, key gene polymorphism on PDIA3 was identified using online databases and analyzed with Haploview software. Third, multivariate‐adjusted logistic regression analyses were employed to evaluate the associations between PDIA3 rs2788 and hypertension. Finally, stratified analyses were conducted to further assess interactions between PDIA3 rs2788 and antihypertensive medications. MR analyses indicated a causal relationship between PDIA3 and hypertension. The rs2788 gene polymorphism locus on PDIA3 was identified using online databases and Haploview software. Multivariable‐adjusted logistic regression analyses revealed that PDIA3 rs2788 was an independent risk for hypertension (OR: 4.603, 95% CI: 2.946–7.194; p < 0.001). Significant interactions were identified between PDIA3 and antihypertensive medications, particularly ACEI/ARB treatments (p = 0.013 for interaction). Similar findings were observed regarding the causal relationship between antihypertensive treatments and hypertension. PDIA3, particularly its rs2788 polymorphisms, may represent a novel biomarker for hypertension. These findings may contribute to the development of targeted screening strategies and personalized treatment approaches for hypertension management.
Association Between Uric Acid to High‐Density Lipoprotein Cholesterol Ratio and Kidney Function in Patients With Primary Aldosteronism: A Cross‐Sectional Study
Authors: Wu Meng‐Bo , Wang Rui , Zeng Qing‐Tian , Shuai Wen‐Liang , Zhang Hang‐Cheng , Dong Yi‐Fei 
Published: December 2024

ABSTRACTThe relationship between the uric acid to high‐density lipoprotein cholesterol ratio (UHR) and kidney function in patients with primary aldosteronism (PA) is unclear. Therefore, this research explored the link between the UHR and kidney function in PAs. This research was conducted at the 2nd Affiliated Hospital of Nanchang University and involved PA individuals hospitalized between October 2017 and April 2022. A total of 653 eligible participants were included in the analysis for this research. The kidney function was assessed by the estimated glomerular filtration rate (eGFR), which is calculated using the modification of diet in renal disease (MDRD) equation. Chronic kidney disease (CKD) was defined as an eGFR <60 mL/min per 1.73 m2 or the ratio of urine microalbumin to creatinine (UACR) ≥30 mg/g. The study used multivariable‐adjusted linear regression analyses to investigate the association between log‐transformed UHR levels and, eGFR and CKD. After multivariable adjustments, the results indicated an inverse association between Lg‐UHR and eGFR (per SD increment; β: −9.02; 95% CI: −11.59, −6.46). Compared to PA patients with the lowest level of Lg‐UHR (T1), patients with the highest level of Lg‐UHR (T3) had a lower eGFR (β: −20.14, 95% CI: −26.25, −14.04). Conversely, Lg‐UHR and CKD showed a positive association cross‐sectionally (per SD increment; OR: 1.67; 95% CI: 1.26, 2.23). Compared to PA patients in T1 level, patients in T3 level had a higher prevalence of CKD (OR: 2.52, 95% CI: 1.26, 5.05). In patients with PA, UHR is inversely associated with eGFR and positively associated with CKD.