bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prospective First‐Trimester Ultrasound Imaging of Low Implantation and Placenta Accreta Spectrum
Authors: Happe Sarah K. , Rac Martha W. F. , Moschos Elysia , Wells C. Edward , Dashe Jodi S. , McIntire Donald D. , Twickler Diane M. 
Published: May 2020

ObjectivesTo prospectively evaluate low implantation of the gestational sac and other first‐trimester ultrasound (US) parameters for prediction of placenta accreta spectrum (PAS).MethodsWomen with a diagnosis of low implantation on clinically indicated first‐trimester US underwent a transvaginal US examination at 10 to 13 weeks’ gestation to assess the trophoblast location, anechoic areas, bridging vessels, and smallest myometrial thickness (SMT). The placental location was evaluated in the second trimester, and serial US examinations were performed in cases of low placentation. Placenta accreta spectrum was based on clinical findings and confirmed by histologic results.ResultsOf 68 women, 40 (59%) had prior cesarean delivery (CD). Hysterectomy was performed in 8, all with prior CD. Of these, 7 (88%) had US suspicion of PAS. In 16 with prior CD and basalis overlying the internal os, 9 (56%) had second‐trimester placenta previa, and 7 of 9 (78%) underwent hysterectomy with pathologic confirmation of PAS. Of 28 without prior CD, there were no cases of persistent low placentation in the third trimester regardless of the trophoblast location. Ultrasound parameters associated with PAS were a smaller distance from the inferior trophoblastic border to the external os, disruption of the bladder‐serosal interface, bridging vessels, anechoic areas, and the SMT. In women with prior CD, use of the SMT in the sagittal plane yielded an area under the receiver operating characteristic curve of 0.96 (95% confidence interval, 0.91–1.00).ConclusionsFirst‐trimester low implantation increases the risk of persistent placenta previa and PAS in women with prior CD. All parameters were associated with PAS, the most predictive being the SMT.
Recent Advances of pH‐Induced Charge‐Convertible Polymer‐Mediated Inorganic Nanoparticles for Biomedical Applications
Authors: Yang Hong Yu , Li Yi , Lee Doo Sung 
Published: May 2020

AbstractThe incorporation of functional polymers and inorganic nanoparticles into nanoplatforms has the potential to produce personalized nanomedicine systems for further biomedical applications. Polymers that endow inorganic nanoparticles with unique surface properties for prolonged blood circulation and improved tumor targeting and cellular uptake are especially desired. pH‐induced charge‐switchable polymers are sensitive to the pH of the tumor environment and maintain a negative or neutral charge in blood circulation, increasing their circulation time and enhancing tumor accumulation via the enhanced permeability and retention effect. This type of polymer further transforms its charge to positive in acidic tumor locations to promote cellular uptake. Furthermore, the combination of pH‐induced charge‐switchable polymers with various inorganic nanoparticles (e.g., magnetic nanoparticles, gold nanoparticles, quantum dots, and upconversion materials) activates their intrinsic functions in in situ diagnosis and disease therapy. This review briefly overviews the recent progress in the development and application of various pH‐induced charge‐convertible polymers functionalized with different types of inorganic nanoparticles for different biomedical applications. More importantly, future developments in this field are also discussed.
Can Ferroelectricity Improve Organic Solar Cells?
Authors: Abdu‐Aguye Mustapha , Doumon Nutifafa Y. , Terzic Ivan , Dong Jingjin , Portale Giuseppe , Loos Katja , Koster L. Jan Anton , Loi Maria Antonietta 
Published: May 2020

AbstractBlends of semiconducting (SC) and ferroelectric (FE) polymers have been proposed for applications in resistive memories and organic photovoltaics (OPV). For OPV, the rationale is that the local electric field associated with the dipoles in a blend could aid exciton dissociation, thus improving power conversion efficiency. However, FE polymers either require solvents or processing steps that are incompatible with those required for SC polymers. To overcome this limitation, SC (poly(3‐hexylthiophene)) and FE (poly(vinylidene fluoride‐trifluoroethylene)) components are incorporated into a block copolymer and thus a path to a facile fabrication of smooth thin films from suitably chosen solvents is achieved. In this work, the photophysical properties and device performance of organic solar cells containing the aforementioned block copolymer consisting of poly(vinylidene fluoride‐trifluoroethylene): P(VDF‐TrFE), poly(3‐hexylthiophene): P3HT and the electron acceptor phenyl‐C61‐butyric acid methyl ester: [60]PCBM are explored. A decrease in photovoltaic performance is observed in blends of the copolymer with P3HT:[60]PCBM, which is attributed to a less favorable nanomorphology upon addition of the copolymer. The role of lithium fluoride (the cathode modification layer) is also clarified in devices containing the copolymer, and it is demonstrated that ferroelectric compensation prevents the ferroelectricity of the copolymer from improving photovoltaic performance in SC‐FE blends.
A 1 V 25 to 30 GHz three‐stage linear CMOS power amplifier using driver stage RF predistortion technique
Authors: Choi Sunkyu , Kim Hyeon‐June , Lee Eun‐Gyu , Choi Han‐Woong , Lim Jeong‐Taek , Kim Choul‐Young 
Published: May 2020

AbstractThis article presents a three‐stage 25 to 30 GHz linear CMOS power amplifier (PA) for fifth‐generation (5G) applications. In order to improve the linearity by compensating AM‐AM/AM‐PM distortion, we propose a driver stage RF predistortion technique in which a first drive amplifier (DA) operates in class C mode and a second DA operates in class A mode. By enhancing the linearity with the technique, the PA can be operated at more deep class‐AB bias condition with less back‐off. As a result, the efficiency of the PA at operating output power can thus be increased. The PA with the predistortion technique is designed and fabricated in bulk 65 nm 1 V CMOS process. The linear PA achieves 16.9 dBm Psat with 34.5% power‐added efficiency (PAE) and 15.9 dBm P1dB with 32% PAE at 27 GHz. At an average power of 9.3 dBm, the PA achieves the EVM of −25 dBc and PAE of 11.4% at 27 GHz.
The Diabetes Risk and Determinants of Transition from Metabolically Healthy to Unhealthy Phenotypes in 49,702 Older Adults: 4‐Year Cohort Study
Authors: Feng Siyuan , Gong Xiaowen , Liu Hongwei , Lu Rui , Duan Tongqing , Wang Mengyang , Wang Jiao , Wang Hui , Chen Jiageng , Liu Yuanyuan , Li Changping , Ma Jun , Liu Hongyan , Wu Linna , Lin Yao , Hou Fang , Zhang Yourui , Liu Hao , Lu Chunlan , Yu Pei , Cui Zhuang 
Published: May 2020

ObjectiveThis study aimed to assess whether metabolically healthy obesity (MHO) increases the risk of diabetes and to explore how the occurrence of metabolic disorders affects the risk of diabetes and which factors determine metabolic health.MethodsThis study examined 49,702 older people without diabetes via the Binhai Health Screening Program in Tianjin.ResultsCompared with individuals with metabolic health and normal weight, the risk of diabetes was increased in older adults with MHO (hazard ratio [HR]: 1.786, 95% CI: 1.407‐2.279) but was not significantly increased when metabolic health was characterized by the absence of metabolic abnormalities. The older adults who were initially affected by MHO and then converted to having an unhealthy phenotype had a higher diabetes risk than older individuals with stable and healthy normal weight (HR: 3.727, 95% CI: 2.721‐5.105). Waist circumference was an independent predictor of the transition from a metabolically healthy status to an unhealthy status in all BMI categories (odds ratio: 1.059, 95% CI: 1.026‐1.032).ConclusionsThe MHO phenotype was associated with an increased incidence of diabetes in older adults. The presence of metabolic disorders in the group with MHO was associated with an increased diabetes risk and was predicted by the waist circumference at baseline.
The influence of amino substituents on the signal‐output, selectivity, and sensitivity of a hydroxyaromatic 1,2,3‐triazolyl chemosensor for anions—A structure–property relationship investigation
Authors: Ghosh Debanjana , Landge Shainaz , Zhu Lei , Ofulue Unodinma , Akinsoji Oluwagbotemi A. , Govan Richard D. , Ugboya Aikohi , Hernandez Vincent , Yates Kayley , Henderson Arneshia , Aiken Karelle S. 
Published: May 2020

AbstractThe influence of strongly electron donating amino groups on a hydroxyaromatic 1,2,3‐triazolyl anion chemosensor was investigated with spectroscopic studies (ultraviolet‐visible [UV‐vis], fluorescence, and nuclear magnetic resonance [NMR]) and computational analyses. This work focused on 2‐, 3‐ and 4‐amino derivatives of the parent molecule, 2‐(4‐phenyl‐1H‐1,2,3‐triazol‐1‐yl)phenol (PTP). The effect on signal‐output, selectivity, sensitivity, and the mechanism of response was explored. In all cases, the incorporation of the amino group enhances fluorescence during anion detection while retaining key properties (the receptor site, a blue‐fluorescent response, and the ability to detect F−, H2PO4−, and AcO−—strongest response to F−). Specifically, sensitivity to F− is impacted by the amino group's location. The 2‐amino is most responsive to F−, more than PTP and the other amino regioisomers. Results from this work are important for developing predictive, structure‐signal tuning models, which will be used in the targeted design of sensors based on the PTP scaffold.
Back Cover
Authors: Zhang Kun , Chen Mengli , Wang Hao , Duan Wenbo , Wang Qiang , Li Fen , Deng Denghui , Bandason Elizabeth , Wu Shaoying 
Published: May 2020

The back cover image is based on the Research Article Molecular characterization and functional expression of voltagegated sodium channel variants in Apolygus lucorum (Meyer‐Dür) by Kun Zhang et al., https://doi.org/10.1002/ps.5748.
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Extended filtering high‐gain output feedback controller for a class of uncertain nonlinear systems subject to external disturbances
Authors: Ma Tong 
Published: May 2020

AbstractIn this article, an extended filtering high‐gain output feedback controller is developed for a class of uncertain nonlinear systems subject to external disturbances. The nonlinearities under consideration satisfy a semiglobal Lipschitz condition. The proposed control architecture integrates the extended state observer (ESO), high gain, and low‐pass filter together. None of them is used alone. The ESO can not only estimate the unknown internal state, but also deliver a good property of disturbance rejection simultaneously due to the presence of high gain. Since the high gain deteriorates the robustness of the system, a low‐pass filtering mechanism is added in the control law to filter away aggressive signals and recover the robustness. The filtering control law is designed to compensate the nonlinear uncertainties and deliver a good tracking performance with guaranteed stability. The matched uncertainties are canceled directly by adopting their opposite in the control signal, whereas a dynamic inversion of the system is required to eliminate the effect of the mismatched uncertainties on the output. Since the virtual reference system defines the best performance that can be achieved by the closed‐loop system, the uniform performance bounds are derived for the states and control signals via comparison. Numerical examples are provided to illustrate the effectiveness of the novel design via comparisons with the model reference adaptive control method and L1 adaptive controller.
Photoelectrocatalytic Reduction of CO2 over CuBi2O4/TiO2‐NTs under Simulated Solar Irradiation
Authors: Cao Huazhen , Yu Hailing , Lu Yueheng , Zhang Huibin , Hou Guangya , Tang Yiping , Zheng Guoqu 
Published: May 2020

AbstractThe present study focused on the photoelectrocatalytic reduction of CO2 on CuBi2O4/TiO2‐NTs(TiO2 nanotube arrays)catalyst under simulated solar irradiation. CuBi2O4 was successfully loaded on TiO2‐NTs via pulse deposition regime from a nitric acid aqueous solution with Bi3+/Cu2+ molar ratio of 2, followed by calcination in air at 450 °C. A series of condition experiments were conducted to obtain excellent‐performance CuBi2O4 film. The crystalline structure, morphology and elemental composition of catalysts were characterized by X‐ray diffractometer(XRD), field‐emission scanning electron microscope (FE‐SEM) and energy dispersive spectroscopy (EDS). Light absorption characteristics were analyzed by ultraviolet‐visible spectrophotometer (UV‐Vis). Experimental results show that the coupling of CuBi2O4 and TiO2‐NTs leads to a better visible light response and photoelectrocatalytic performance for CO2 reduction. The photocurrent on CuBi2O4/TiO2‐NTs electrode increases significantly compared with that on TiO2‐NTs. Under optimized experimental condition, the photocurrent is up to 0.5 mA cm−2 at potential of −0.5 V vs. SCE. The liquid products determined by Gas Chromatograph are mainly composed of ethanol with minor formaldehyde.
Electrochemical Evaluation of Folic Acid by Low Concentration of Methylene Blue Coated on a Green‐Synthesized ZnO Nanoparticles Suspension Solution
Authors: Hashemnia Sedigheh , Mokhtari Zaynab , Solati Zahra , Azimpanah Razieh , Nikoozad Mahsa 
Published: May 2020

AbstractHere, we have reported an effective and simple electrochemical technique to determine folic acid (FA) in a colloidal suspension solution containing FeIII ion, methylene blue (MB) surface‐coated ZnO nanoparticles (MB@ZnONPs) and sodium dodecyl sulfate (SDS) (FeIII/MB@ZnONPs/SDS). MB, and ZnONPs were used as redox indicator and signal amplification element respectively. Low‐concentration of MB (2.5 μM) strongly is maintained at ZnONPs surface. SDS was used to improve the dispersion stability of the suspension. ZnONPs were synthesized through biological pathway using cordia myxa leaves extract. To investigate physicochemical properties of ZnONPs and MB@ZnONPs, fourier‐transform infrared spectra, nitrogen desorption/adsorption isotherms, field emission scanning electron microscopy and energy dispersive X‐ray spectroscopy were used. Cyclic voltammetry and differential pulse voltammetry showed the positive effect of FeIII ion, on the redox behavior of the suspension solution, probably due to inhibiting effect of this cation on the agglomeration of MB@ZnONPs/SDS suspension. Addition of FA to suspension solution, caused a sharp decrease in the peak current. Therefore, the colloidal suspension solution employed as an analytical probe for FA determination. The response of the probe showed a linear dependence on the logarithm of FA concentration in the range of 1.42 nm to 3.30 μM (I/μA=‐0.26 Log [FA]+0.03, R2=0.99). The calculated limit of detection was 0.98 nM.
Core‐Shell Structured Bi‐Amorphous SiO2@TiO2 Composite for Lithium‐Ion Batteries Anode Material with Ultra‐Stable Performance
Authors: Yao Yixin , Li Yao , Li Cheng , Zhou Junshuai , Wu Qibing , Zheng Yan‐Zhen , Wu Jiaojiao , Zhou Zhou , Ding Haiyang , Tao Xia 
Published: May 2020

AbstractSurface coating strategies have shown to be effective for improving the cyclability of SiO2 anode materials of lithium‐ion batteries (LIBs). Herein, we prepared commercially amorphous SiO2 nanoparticles encapsulated in amorphous titanium oxide shells (a‐TiO2) (SiO2@a‐TiO2) by a facile hydrolysis of titanium isopropylate in alkaline alcohol system. The elastic a‐TiO2 shell can mitigate the volume change of amorphous SiO2 in the lithiation/delithiation processes and improve the electrical conductivity of SiO2‐based anodes. By delicately optimizing the a‐TiO2 shell (12.18 wt.%), SiO2@a‐TiO2 composite delivers a superior cycling capacity of 647 mA h g−1 at a current density of 0.1 A g−1 after 300 cycles, corresponding to an admirable capacity retention rate of 87.3% from the 2nd to 300th cycle. The SiO2@a‐TiO2 composite with core‐shell structures has outstanding electrochemical performance, which is prepared by a low‐cost and facile solution approach, thus it is expected to realize the large‐scale production of SiO2‐based anode materials.
Enzyme Mimics for the Catalytic Generation of Nitric Oxide from Endogenous Prodrugs
Authors: Yang Tao , Zelikin Alexander N. , Chandrawati Rona 
Published: May 2020

AbstractThe highly diverse biological roles of nitric oxide (NO) in both physiological and pathophysiological processes have prompted great interest in the use of NO as a therapeutic agent in various biomedical applications. NO can exert either protective or deleterious effects depending on its concentration and the location where it is delivered or generated. This double‐edged attribute, together with the short half‐life of NO in biological systems, poses a major challenge to the realization of the full therapeutic potential of this molecule. Controlled release strategies show an admirable degree of precision with regard to the spatiotemporal dosing of NO but are disadvantaged by the finite NO deliverable payload. In turn, enzyme‐prodrug therapy techniques afford enhanced deliverable payload but are troubled by the inherent low stability of natural enzymes, as well as the requirement to control pharmacokinetics for the exogenous prodrugs. The past decade has seen the advent of a new paradigm in controlled delivery of NO, namely localized bioconversion of the endogenous prodrugs of NO, specifically by enzyme mimics. These early developments are presented, successes of this strategy are highlighted, and possible future work on this avenue of research is critically discussed.
Development and validation of assay and impurities methods for acetaminophen and diphenhydramine tablets
Authors: Kirkpatrick Douglas , Momot Magdalene , Anthony Clydewyn 
Published: May 2020

AbstractThe United States Pharmacopeia compendium does not currently contain a documentary standard for acetaminophen and diphenhydramine hydrochloride tablets to determine quality. To address this gap, high‐performance liquid chromatography methods for assay and impurities were developed and validated. Marketed products contain different amounts of drug substances per unit (325–500 mg of acetaminophen and 12.5–25 mg of diphenhydramine), so two methods specific to each substance were required. Methods were designed for high throughput by limiting analysis time, and complexity was reduced by utilizing similar materials and instrumental configurations across methods. For each method, specificity, linearity, accuracy, and precision were demonstrated for the assay and impurity determination. Both methods were shown to be fit‐for‐purpose and may be considered for adoption as United States Pharmacopeia compendial standards.
Integrierter Hebeprozess für hybride Gittermastrohrtürme der Windenergie
Authors: Richter Carl , Pak Daniel , Rebelo Carlos , Mohammadi Mohammad Reza Shah 
Published: May 2020

AbstractHöhere Ausbeute an Windenergie bedeutet höhere Windtürme. In einem vom Research Fund for Coal and Steel (RFCS) geförderten Projekt „Steel Hybrid Onshore Wind Towers Installed with Minimal Effort“ (SHOWTIME) wurde sich mit der Frage beschäftigt, wie sehr große Nabenhöhen (> 180 m) wettbewerbsfähig in Stahlbauweise realisiert werden können. Als Lösung wird ein Stahlhybridturm mit einem unteren Teil in Gittermastbauweise und einem oberen Teil in Rohrvollwandbauweise angestrebt. Da Mobilkräne zur Erreichung solcher Nabenhöhen teuer und teilweise gar nicht verfügbar sind, wurde nach alternativen Möglichkeiten gesucht, den Turm zu errichten. So wurde ein integriertes Hebekonzept entwickelt, mit dem das obere Rohrteil am Übergangsstück per Litzenhub nach oben gehoben wird. Wichtig in diesem Zusammenhang ist auch die temporäre Verbindung der beiden Turmteile im Übergangsstück während des Hebevorgangs, da ein Verkippen des Rohrturms während des Hubs verhindert werden muss. In diesem Beitrag werden der innovative Hebevorgang und verschiedene Schritte zur Auslegung des Hebevorgangs und des Übergangsstücks sowie der durchgeführte Demonstrationsversuch vorgestellt.
Asymmetrical LVRT of DFIG incorporating feed‐forward transient current control and controllable resistive‐type fault current limiter
Authors: Huang Jiejie , Li Shenghu 
Published: May 2020

AbstractDuring the low‐voltage ride‐through (LVRT) of the doubly fed induction generator (DFIG), the change rate of the stator flux is introduced as the feed‐forward compensation (FFC) to prevent the stator flux oscillation from affecting the rotor current control. The dual‐sequence FFC is proposed for the asymmetrical LVRT of the DFIG. To reduce the rotor voltage increase due to the FFC, the controllable resistive‐type fault current limiter (CRTFCL) is implemented at the stator side to improve damping to the stator flux oscillation. The resistance of the CRTFCL is controlled based on the ramp function to relieve oscillations resulted from the switch‐out of the CRTFCL. With the dual‐sequence FFC and CRTFCL applied to the asymmetrical LVRT, analytical expressions of the stator current, rotor current, and rotor voltage are derived. The accuracy of the analytical expressions and the improved LVRT performance with the dual‐sequence FFC and the CRTFCL are verified based on the time‐domain simulations. © 2020 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
Entanglement contour and modular flow from subset entanglement entropies
Authors: Wen Qiang 
Published: May 2020

AbstractThe Entanglement contour function quantifies the contribution from each degree of freedom in a region $$ \mathcal{A} $$
A
to the entanglement entropy $$ {S}_{\mathcal{A}} $$

S
A

. Recently in [1] the author gave two proposals for the entanglement contour in two-dimensional theories. The first proposal is a fine structure analysis of the entanglement wedge, which applies to holographic theories. The second proposal is a claim that for general two-dimensional theories the partial entanglement entropy is given by a linear combination of entanglement entropies of relevant subsets inside $$ \mathcal{A} $$
A
. In this paper, we further study the partial entanglement entropy proposal by showing that it satisfies all the rational requirements proposed previously. We also extend the fine structure analysis from vacuum AdS space to BTZ black holes. Furthermore, we give a simple prescription to generate the local modular flows for two-dimensional theories from only the entanglement entropies without refer to the explicit Rindler transformations.