bluuebunny/crossref_metadata_2025_split huggingface dataset:
Obstruktív koszorúér-betegség nélkül kialakuló heveny szívizominfarktus (MINOCA) – gyakoriság és prognózis
Authors: Jánosi András , Ferenci Tamás , Kőszegi Zsolt , Nagy Gergely György , Jambrik Zoltán , Ruzsa Zoltán , Lupkovics Géza , Csanádi Zoltán , Becker Dávid , Merkely Béla , Andréka Péter 
Published: November 2019

Abstract: Introduction: There are conflicting data on the prevalence and prognosis of AMI patients with non-obstructive coronary artery disease (MINOCA). Aim: We studied the prevalence and prognosis of MINOCA patients. Method: In the Hungarian Myocardial Infarction Registry (HUMIR) 45,223 patients (pts) with acute myocardial infarction (AMI) were found who were treated between Jan 1, 2014, and June 30, 2018, and coronary arteriography was performed. ST-elevation myocardial infarction was diagnosed in 22,469 pts (49.7%). Patients without obstructive coronary artery disease who had no previous myocardial infarction, heart failure, PCI and CABG procedure were selected to the MINOCA group (n = 2003). Patients with obstructive coronary artery disease belonged to the MICAD group (n = 43,220). We investigated clinical characteristics of the patients, overall survival and reinfarction. Survival curves were estimated with the Kaplan–Meier method and were modeled with the Cox proportional hazards model. Results: The proportion of MINOCA pts among all myocardial infarction was by 4.4% higher in the STEMI pts compared to the NSTEMI group (2.0% vs. 6.8%). The MINOCA pts were younger (age 64.0 ± 14.4 vs. 65.5 ± 12.2 years), and the proportion of women was higher (55.7% vs. 36.5%). Hypertension, diabetes mellitus and peripheral artery disease were more common in the MICAD group (79.1% vs. 73.7%, 33.0% vs. 21.2%, and 12% vs. 8%). The mortality was higher among the MICAD pts. In the MINOCA group, the mortality of men did not differ between STEMI and NSTEMI, as opposed to women: women with STEMI had higher mortality than women with NSTEMI. The risk of reinfarction was higher in the MICAD group, especially in NSTEMI, the risk in the MINOCA group was lower, and there was no substantial difference between types. Conclusion: In this real word, retrospective, observational study, we found a significant difference in the prevalence of MINOCA pts according to different types of myocardial infarction. In the MINOCA group, the mortality of women with STEMI was substantially higher. Orv Hetil. 2019; 160(45): 1791–1797.
Mit tudunk az e-cigaretta káros hatásairól?
Authors: Nagy László Béla 
Published: November 2019

Abstract: Electronic cigarettes are becoming increasingly popular with smokers worldwide. This has created an entirely new public health dilemma. The central issue in the debate is the disease risk imposed by e-cigarettes. It is generally acknowledged that e-cigarettes are unlikely to be as harmful as conventional cigarettes, but there are little data that quantify their relative harms. Experiments in cell cultures and animal studies show that e-cigarettes can have multiple negative effects. Scientific evidence regarding their human acute health effects is limited. The long term effects in humans are unknown, and there is no evidence that e-cigarettes are safer than tobacco in the long term. This review higlights the recent data regarding e-cigarettes toxicity impact on lung and cardiovascular system. Orv Hetil. 2019; 160(45): 1767–1773.
Association of T715P (RS6136), M62I (RS2228315), S290N (RS6131), V640L (RS6133) polymorphisms in the P-selectin gene and its ligand with acetylsalicylic acid resistance in patients with coronary artery disease after coronary artery bypass grafting
Authors: Kosinova A. A. , Mongush T. S. , Goncharov M. D. , Subbotina T. N. , Semashchenko K. S. , Kochmareva G. Yu. , Grinshtein Yu. I. 
Published: November 2019

Aim.To study the association of T715P (rs6136), M62I (rs2228315), S290N (rs6131), V640L (rs6133) polymorphisms in the P-selectin gene with resistance to acetylsalicylic acid (ASA) in patients with coronary artery disease after coronary artery bypass grafting (CABG).Material and methods. The study included 90 patients aged 61,5±6,9 years (70 men and 20 women) with II-IV functional class (FC) angina pectoris, according to the Canadian Cardiovascular Society grading. The atherosclerotic nature of coronary artery disease is confirmed by coronary angiography. Patients stopped taking antiplatelet agents before CABG for at least 5 days. The aggregation study was carried out with an optical aggregometer using ADP inducers (5 pM) and arachidonic acid (1 µМ) before CABG, on 1-3 and 8-10 days after surgical treatment.DNA samples were examined for the presence of T715P (rs6136), M62I (rs2228315), S290N (rs6131), V640L (rs6133) polymorphisms in the P-selectin gene using realtime PCR with allele-specific primers.Results.When comparing aPTT, fibrinogen level, platelet aggregation activity with ADP inducers (5 µМ) and arachidonic acid (1 µМ), no differences were found among groups of patients with homozygous and heterozygous variants of the studied polymorphisms genotypes, both before and on 1-3, 8 -10 days after CABG. Regarding presence of ASA resistance, patient groups with homozygous variants of genotypes (T715P (rs6136), M62I (rs2228315), S290N (rs6131), V640L (rs6133)) did not statistically differ in prevailing or rare alleles from the corresponding groups with heterozygous genotypes. In the first 10 days of the postoperative period, thrombotic events (4,4%) were observed in 4 patients in the study group: acute myocardial infarction, acute cerebrovascular accident. Regarding frequency of adverse events in the first 10 days after CABG, between groups of patients with homozygous variants of the studied genotypes (T715P (rs6136), M62I (rs2228315), S290N (rs6131), V640L (rs6133) in prevailing allele and groups with heterozygous variants of the corresponding genotypes there were also no statistically significant differences.Conclusion.Rs6133, rs6163, rs2228315, rs6131 polymorphisms in the platelet P-selectin gene are not associated with ASA resistance and are not associated with increased platelet aggregation activity in patients with coronary artery disease. The rare T, C, G, A alleles of the studied polymorphisms do not lead to an increase in the risks of adverse events in the first 10 days after CABG.
Association of single nucleotide polymorphisms rs7164665, rs71461059, rs74765750, rs6762529 with sudden cardiac death
Authors: Ivanova A. A. , Maksimov V. N. , Malutina S. K. , Novoselov V. P. , Voevoda M. I. 
Published: November 2019

Aim. To confirm the association between sudden cardiac death (SCD) and single nucleotide polymorphisms rs7164665, rs71461059, rs74765750, rs6762529, identified in own genome-wide associative study as new molecular genetic markers of SCD.Material and methods. As design we used case-control study. The SCD group was formed using the SCD criteria of the European Society of Cardiology (n=438, average age 53,2±9,1 years, male — 72,7%, women — 28,3%). The control group (n=435, average age 53,2±8,9 years, men — 70,0%, women — 30,0%) was selected by gender and age for the SCD group from the DNA bank of the international projects MONICA and HAPIEE. DNA was isolated by phenol-chloroform extraction from myocardial tissue in the SCD group and venous blood in the control group. Genotyping was performed by polymerase chain reaction followed by analysis of estriction fragment length polymorphism. The results are statistically processed using the SPSS 16.0 software package.Results. No carriers of the rare allele A of the single nucleotide polymorphism rs74765750 were found in the SCD group and the control group. No statistically significant differences were found between the SCD group and the control group relating to frequencies of genotypes and alleles of single nucleotide polymorphisms rs7164665 and rs71461059. In the age group older than 50 years, the proportion of carriers of the heterozygous CT genotype of the single nucleotide polymorphism rs6762529 in the SCD group is statistically significantly lower compared to the control group (CT vs CC+TT: OR=0,686, 95% CI 0,483-0,967 p=0,035).Conclusion. The CT genotype of the single nucleotide polymorphism rs6762529 is associated with a protective effect on SCD for people over 50 years of age. The association with single nucleotide polymorphisms rs7164665, rs71461059, rs74765750 with SCD has not been confirmed.
A study to assess the clinical profile of patients with snake bites in a tertiary care hospital
Authors: M. R. Keshava Murthy , Ramesh Aruna C. 
Published: November 2019

Background: Snakebite is a life-threatening medical emergency. It occurs frequently among rural people, especially those working in the fields. Most houses in rural areas of India are made of mud and have many crevices where rodents flourish. Delay in seeking medical aid or ignorance among primary care physicians about the correct treatment of snakebite is responsible for the high morbidity and mortality. Authors objective was to study the clinical profile of snake bite at a rural tertiary care centre.Methods: A hospital based cross sectional study was conducted at M S Rammaih Medical College Bangalore from June 2017 to June 2018. The incidence of Snake bite in Karnataka is 0.5% and at 95% confidence interval with Margin of error at 1% the estimated sample size was 197, but in this study author were able to collect data of 237 cases, hence all the cases were included in the study and analyzed.Results: Majority of the respondents were middle aged between 21-50 years. Around 63.3% of the respondents were male and nearly 56.2% were farmers. The incidence of snake bite of Cobra was seen in 8.9%, Krait 5.1% and viper 4.2%. Around 70% patients had no significant complications following hospitalization in our study. Around 20% had hematotoxic like ARF, DIC and local gangrene.Conclusions: Snakebite is one of the common hazards especially in rural setup as agriculture being the main occupation. Snake bite can present with various manifestations at bite sites, neurotoxicity, hematotoxicity.
THE ACADEMIC PRACTICE OF COMPARATIVE LITERATURE IN ASSAM: THE ROLE OF DIBRUGARH AND GAUHATI UNIVERSITY
Authors: Sarmah Pallabika , Saikia Samutjal 
Published: November 2019

Purpose: This paper aims to present a picture of the evolution, present condition and the prospect of Comparative Literature in the academic world of Assam by mainly giving example of the numerous works done on the discipline in Assam, the syllabus of Dibrugarh and Gauhati University and the research works and projects done in these respective universities.
Methodology: The research methods mainly used in this study are analytical and survey methods. The necessary materials are collected from library and used, with proper observation and analysis, to justify the proposed ideas.
Main Findings: This paper, with clear data, seems to cast light on the trajectory of Comparative Literature in Assam, especially of the present situation and with the observation of these data, an effort is made to get a view of its prospect.
Application: Besides getting acquainted with the evolution of the discipline of Comparative Literature in Assam, this paper seems to be beneficial in comprehending the required adaptation and changes for the discipline in the current situation.
Novelty/Originality: The significance of this paper lies in its effort to give a critical look at the discipline from its beginning to the present situation and most importantly, the discussion of the lacks and faults of its practice and of various steps for the development of the discipline in the state will be very relevant and instrumental in the context of Assam.
EMIRATI WOMEN’S PERCEPTIONS OF POLYGAMY ACCORDING TO AGE, EMPLOYMENT, AND EDUCATIONAL LEVEL
Authors: M. AL-Tkhayneh Khawlah , Khamis Nser Khaled 
Published: November 2019

Purpose of the study: The study investigates the Emirati Women’s perceptions of polygamy according to three variables, namely age, employment, and educational level. It also explores where there are possible reasons that may drive these women to accept polygamy in certain circumstances and their reactions if it actually happens.
Methodology: To achieve this, semi-structured interviews were conducted with 50 Emirati women to get more insight into their choice, reasons, and reactions.
Main findings: The results reveal that 88% of the participants refused the entire idea of polygamy while the rest accepted it. The results also show that the three social variables played an important role in their choice. The participants who consented to polygamy did so due to religious and cultural reasons. In case the husband went along with his remarriage, the participants indicated that they would file for divorce, especially those who are young and employed, or stay with their husbands unhappy. The latter were mostly older and unemployed.
Applications of this study: The Emirati women’s concerns of polygamy and its consequences on family life should be taken into account when revising social policies in the UAE.
The originality of this study: The study is one of its kinds to address polygamy in the UAE. It contributes to the body of knowledge through identifying Emirati women’s concerns of polygamy and discussing the reasons for accepting/rejecting polygamy.
PROJECT MANAGEMENT IMPLEMENTATION IN GOVERNING INSTITUTIONS OF RUSSIA: AIMS AND RESULTS
Authors: A. Lomovceva Olga , A. Tkhorikov Boris , A. Gerasimenko Olga , V. Sobolev Aleksandr , A. Merezhko Anna 
Published: November 2019

Purpose: The article views applied aspects of an important scientific problem - efficiency improvement of state management based on project management that allows solving complex tasks under the conditions of severe restrictions in time, financial and other resources.
Methodology: Methodical approach to project management includes process and targeted approaches that provide current operating activity long with innovative solutions implementation.
Result: The article proves the implementation approach of project management in governing institutions based on the corporate culture, motivation and employee competencies transformation.
Applications: This research can be used for universities, teachers, and students.
Novelty/Originality: In this research, the model of Project Management Implementation In Governing Institutions of Russia: Aims and Results are presented in a comprehensive and complete manner.
DEVELOPMENT OF THE PROCEDURE OF TESTING WITH THE APPLICATION OF THE EXPERT EVALUATION METHOD IN PSYCHOPHYSIOLOGY
Authors: V. Igrunova Svetlana , V. Nesterova Elena , D. Ivaschuk Orest , G. Nesterov Valery , V. Lomazov Alexandr , K. Igrunov Konstantin 
Published: November 2019

Purpose: This article provides a detailed description of the stages of development of an information system of personalized psychophysiological testing using expert evaluation. The process of the information system design is presented, the developed functional models, database and algorithm of testing by students-experts are demonstrated.
Methodology: As a result of the analysis, the features of commercial educational institutions in the field of practical psychology, as the main influencing factor can be identified as the amount of practical training in the direction of «Psychology», which is very different from the standard curriculum.
Result: In the learning process, students, who acts experts, face following problems: absence of a clear structured hierarchy of indicators (test questions) in the evaluation of tests; lack of a procedure for formalization and evaluation of various qualitative and quantitative indicators (certain types of tests; lack of an effective tool that provides support for decision-making on the selection of personality type. The proposed system will solve these problems.
Applications: This research can be used for universities, teachers, and students.
Novelty/Originality: In this research, the model of Development of the Procedure of Testing with the Application of the Expert Evaluation Method in Psychophysiology is presented in a comprehensive and complete manner.
DEVELOPING SOCIAL EMOTIONAL INTELLIGENCE THROUGH PLAYING ACTIVITIES FOR EARLY CHILDHOOD
Authors: Astuti Yuni , Prajana Andika , Damrah  , Erianti  , Pitnawati  
Published: November 2019

Purposes of the study: The purpose of this study was to describe the way to develop social-emotional intelligence in early childhood through play activities. A child doesn’t have social Emotional intelligence naturally in early childhood, but it must be nurtured and developed by parents and teachers in schools through developing social and emotional aspects of early childhood that can be done with various methods.
Methodology: This study used a qualitative approach to the literature model. The method used in this study is a qualitative method with content analysis techniques consisting of developing the social and emotional aspects of early childhood is through playing activities.
Result: The researcher found that playing activities by children can develop social-emotional of early childhood among others. The activities such as playing in small groups like children’s traditional games or playing with tools such as balls, marbles, rubber and, other tools.
Implication/Applications: The findings of this study can help young children to be able to improve the development of social-emotional intelligence caused by hereditary factors and the environment through play activities. In this play, the activity can increase positive attitudes including honest behavior, independence, responsibility, fair, confident, fair, loyal friends, and the nature of compassion towards others and have high tolerance and demanded cooperation between others
A STUDY OF POST-DEMONETIZATION IMPACT OF LIMITED-CASH RETAILING IN UTTARAKHAND, INDIA
Authors: Kandpal Vinay , Mehrotra Rajat , Gupta Sumeet 
Published: November 2019

Purpose of Study: The paper aims to assess the new face of retailing after demonetization with specific focus to the role of financial intermediaries and it also focuses on Long term solutions to drive the digital cash enabled retailing in India.
Methodology: This study used a questionnaire for data collection among 250 retailers in Uttarakhand, India. The questionnaire was later on analyzed using SPSS. Qualitative data was gathered from the interview with the officials from 100 financial intermediaries from banks.
Findings: The Indian retail market has been fostered by the cash dealings. The step of demonetization caught the black marketers, retailers and common people by surprise. The move was supported by the majority of people despite facing difficulties. After the demonetization, people started using the adoption of different forms of digital payment options. The trade in the market was affected and the retail sales witnessed a severe dip. The market is recovering but the actual recovery will depend on devising the substitute for the cash payments at all levels of retailers.
Social implications: Financial inclusion is important for inclusive growth and bank to have a crucial role to play in financial literacy campaigns and should ensure that those deprived sections that come to exchange their old notes are properly taken care of. Banks could make unbanked people aware about the financial instruments available with banks and the importance of saving and putting their money in these instruments. This step would further help the economy move from unorganized to organized sector.
The originality of Study: This study is original and first of its kind conducted in Uttarakhand, India.
Relation between Self-efficacy and Creative Thinking at Writing Skill Learning
Authors: Deviana Ade Destri , Asri Fauzi , Rusuly Usfiyatur 
Published: November 2019

Self-efficacy is a person's belief in his ability to solve planned activities. Self-efficacy reflects a person’s confidence in their ability to perform tasks creatively and optimistically. The elements to Self-efficacy are mastery experience, vicarious experience, social persuasion, affecative physiological states. Creative thinking is ability to find new ideas originally that are surprising to define it, and also valuable in sensitivity, and the factors are fluency, flexibility, originality, sensitivity, and elaboration. Learning at class need self-efficacy and creative thinking based, the both have relation that influence. Researcher will reveal it at writing skill learning. This study aims at investigating the relationship between self-efficacy and creative thinking of university students at writing skill learning. The method uses quantitative with correlation of two variables with paired sample test. The subject of the study is 53 third semester students of Arabic Language Education Department of Arabic Literature Faculty of State University of Malang Indonesia at writing skill class. Its coefficient correlation is 0,799 and p-value 0,000. The result of this study indicates significant correlation between self-efficacy and creative thinking at writing skill learning. The Fact, self-efficacy increased so creative thinking increased much and otherwise. The Teacher has important role of writing skill learning as facilitator or instructor so that the students like the learning and enhancement of trust.
Learning Innovation Management on Effective Classes at SMPIT Cordova Samarinda
Authors: Hanim Zaenab , Masyni Masyni , Soe`oed Rahmad , Asiah Siti Nor 
Published: November 2019

The research is intended to find out (1) the concept of learning innovation, (2) the implementation of learning innovation management functions, (3) the implication of learning innovation management, and (4) obstacles and solutions of the implementation of learning innovation management at effective classes at Integrated Islamic Secondary School (SMPIT) Cordova Samarinda. This research used a qualitative approach with case study and the data was collected through deep interview, observation and documentation. The informans of the research are the head and his vice of the foundation, coordinator of the effective classes, teachers and students. The data was analysed by using descriptive technique. For the research findings, it was found that (1) the concept of learning innovation for effective classes is built through middle input with an effective learning process and produces an effective output; (2) the implementation of learning innovation management functions of effective classes was carried out through planning design by determining input sellection standard, an effective process standard, an effective output standard, learning innovation organization through enriched curriculum, time allocation, teachers’ roles and duties, learning sources, learning innovation through moving class, a standardized teachers, IT-based management, full day school program, and three evaluations of learning innovation, namely test and non-test with mastery learning standard, and high competition class assessment; (3) the implication of learning innovation management covers integrated learning management system, better teacher qualification standard, and increase school reputation; and (4) obstacles and solution disrupt the implementation of learning innovation management of effective classes at SMPIT Cordova Samarinda.