bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing Mucus Clearance by Cough Through Repeated Pulses
Authors: Tuna Duygu L. , Ünal Mehmet Altay , Arı Fikret , Krumpe Peter , Evrensel Cahit A. 
Published: June 2020

AbstractThe aim of this study is to investigate the potential increase in the efficiency of the mucus clearance by repeated pulses of the same maximum speed and total air volume compared to single pulse simulated cough and to explore the effect of mucus simulant rheology and duration between repeated pulses on it. Experiments are conducted to study the behavior and clearance of a mucus simulant through a D-shaped rigid plexiglass horizontal tracheal model by approximately rectangular pulses. Mucus simulants with viscoelastic properties like mucus of patients with chronic obstructive pulmonary disease (COPD) or similar illnesses, a moderate increase in elastic modulus, and a sharp decrease in viscosity with increasing frequency were prepared by locust bean gum and borax-de-ionized water solutions (Ragavan, A. J., Evrensel, C. A., and Krumpe, P., 2010, “Interactions of Airflow Oscillation, Tracheal Inclination, and Mucus Elasticity Significantly Improve Simulated Cough Clearance,” Chest, 137(2), pp. 355–361). Displacement of 0.3 ml mucus simulant aliquot is measured during single or repeated airflow pulses with a total air volume of about 1.1 L and the same maximum velocity. The desired flow pattern is generated by a compressor set at 4.5 bar and a computer-controlled on–off valve. Displacement of the same volume of mucus aliquot increases with the increasing number of pulses with the same total volume of air and maximum velocity and increasing of elasticity of mucus simulants. The increased maximum airflow velocity of repeated pulses affects the displacement of mucus aliquot positively. Moreover, when the duration length between the repeated pulses increased up to 100 ms, the displacement of aliquot increased up to but after 100 ms to 150 ms started to decrease.
Heat Transfer From a Heated Flat Surface Due to Swirling Coaxial Turbulent Jet Impingement
Authors: Afroz Farhana , Sharif Muhammad A.R. 
Published: May 2020

Abstract
Heat transfer from an isothermally hot flat surface due to swirling coaxial turbulent jet impingement is investigated numerically. The coaxial jet construction consists of implanting a thin-walled round tube inside a coaxial outer pipe. Two different fluid streams or jets, having different average velocities, flow through the inner tube, and the annular space between the inner tube and the outer pipe. The ratio of the average velocities of the jets, the ratio of the pipe diameters, the jet exit Reynolds number, the strength of the swirl, and the separation distance from the jet exit to the impingement surface are the main parameters for this flow configuration. The effects of the swirl strength on the jet impingement heat transfer at the target surface are investigated by computing the flow and thermal fields for various combinations of the problem parameters. The presented results contain the plots of the flow streamlines, the contours of the temperature, the contours of the swirl velocity, as well as the distribution of the local and average Nusselt number on the impingement surface. It is found that, compared to the single round jet, the coaxial jet produces enhanced and more uniform heat transfer at the heated surface. The jet-spreading and mixing are affected by the imposed jet swirl which modifies the heat transfer process. Thus, the heat transfer compared to a non-swirling jet is either enhanced or diminished depending on the combination of the problem parameters.
Predictable patterns in stacking and distribution of channelized fluvial sand bodies linked to channel mobility and avulsion processes
Authors: Sahoo Hiranya , Gani M. Royhan , Gani Nahid D. , Hampson Gary J. , Howell John A. , Storms Joep E.A. , Martinius Allard W. , Buckley Simon J. 
Published: June 2020

Abstract
Despite the importance of channel avulsion in constructing fluvial stratigraphy, it is unclear how contrasting avulsion processes are reflected in stratigraphic-stacking patterns of channelized fluvial sand bodies, as a proxy for how river depocenters shifted in time and space. Using an integrated, geospatially referenced, three-dimensional data set that includes outcrop, core, and lidar data, we identify, for the first time in an outcrop study, a predictive relationship between channelized sand body architecture, paleochannel mobility, and stratigraphic-stacking pattern. Single-story sand bodies tend to occur in vertically stacked clusters that are capped by a multilateral sand body, indicating an upward change from a fixed-channel system to a mobile-channel system in each cluster. Vertical sand body stacking in the clusters implies reoccupation of abandoned channels after “local” avulsion. Reoccupational avulsion may reflect channel confinement, location downstream of a nodal avulsion point that maintained its position during development of the sand body cluster, and/or aggradation and progradation of a backwater-mediated channel downstream of a nodal avulsion point. Sand body clusters and additional multilateral sand bodies are laterally offset or isolated from each other, implying compensational stacking due to “regional” switching of a nodal avulsion point to a new, topographically lower site on the floodplain. The predictive links between avulsion mechanisms, channel mobility, and resultant sand body distributions and stacking patterns shown in our findings have important implications for exploring and interpreting spatiotemporal patterns of stratigraphic organization in alluvial basins.
Magma recharging beneath the Weishan volcano of the intraplate Wudalianchi volcanic field, northeast China, implied from 3-D magnetotelluric imaging
Authors: Gao Ji , Zhang Haijiang , Zhang Senqi , Xin Hailiang , Li Zhiwei , Tian Wei , Bao Feng , Cheng Zhengpu , Jia Xiaofeng , Fu Lei 
Published: June 2020

AbstractThe last volcanic eruptions at the intraplate Wudalianchi volcanic field in northeast China were ∼300 yr ago. Recent ambient noise tomography (ANT) imaged a potential magma chamber beneath one of its volcanoes, the Weishan volcano, which last erupted at ca. 50 ka. To image the spatial distribution of the magmatic system and estimate the melt fractions beneath the Weishan volcano, we use a dense magnetotelluric (MT) network (average site spacing of ∼1 km) around the Weishan cone to image a three-dimensional (3-D) resistivity structure beneath the volcano. For the first time, 3-D MT inversion illuminates the high-resolution spatial distribution of a very low-resistivity body of ∼0.3–3 Ω·m at depth of ∼2–15 km beneath the Weishan volcano. From the 3-D resistivity model, it can be deduced there exists a magma chamber in the upper and middle crust. From both low-velocity anomalies from ANT and low-resistivity anomalies from MT imaging, melt fractions of magma reservoirs are reliably estimated to be &gt;∼15%. From the morphology of magma reservoirs and the shallow magma chamber, the Weishan volcano can be best described by the model of transcrustal magmatic system. Considering the significant melt fractions and active earthquakes and tremors occurring around magma reservoirs, the Weishan volcano is likely in an active stage with magma recharging. Therefore, it needs more active monitoring for better forecasting of its potential future eruptions.
‘Turning the tide’ on hyperglycemia in pregnancy: insights from multiscale dynamic simulation modeling
Authors: Freebairn Louise , Atkinson Jo-an , Qin Yang , Nolan Christopher J , Kent Alison L , Kelly Paul M , Penza Luke , Prodan Ante , Safarishahrbijari Anahita , Qian Weicheng , Maple-Brown Louise , Dyck Roland , McLean Allen , McDonnell Geoff , Osgood Nathaniel D 
Published: June 2020

IntroductionHyperglycemia in pregnancy (HIP, including gestational diabetes and pre-existing type 1 and type 2 diabetes) is increasing, with associated risks to the health of women and their babies. Strategies to manage and prevent this condition are contested. Dynamic simulation models (DSM) can test policy and program scenarios before implementation in the real world. This paper reports the development and use of an advanced DSM exploring the impact of maternal weight status interventions on incidence of HIP.MethodsA consortium of experts collaboratively developed a hybrid DSM of HIP, comprising system dynamics, agent-based and discrete event model components. The structure and parameterization drew on a range of evidence and data sources. Scenarios comparing population-level and targeted prevention interventions were simulated from 2018 to identify the intervention combination that would deliver the greatest impact.ResultsPopulation interventions promoting weight loss in early adulthood were found to be effective, reducing the population incidence of HIP by 17.3% by 2030 (baseline (‘business as usual’ scenario)=16.1%, 95% CI 15.8 to 16.4; population intervention=13.3%, 95% CI 13.0 to 13.6), more than targeted prepregnancy (5.2% reduction; incidence=15.3%, 95% CI 15.0 to 15.6) and interpregnancy (4.2% reduction; incidence=15.5%, 95% CI 15.2 to 15.8) interventions. Combining targeted interventions for high-risk groups with population interventions promoting healthy weight was most effective in reducing HIP incidence (28.8% reduction by 2030; incidence=11.5, 95% CI 11.2 to 11.8). Scenarios exploring the effect of childhood weight status on entry to adulthood demonstrated significant impact in the selected outcome measure for glycemic regulation, insulin sensitivity in the short term and HIP in the long term.DiscussionPopulation-level weight reduction interventions will be necessary to ‘turn the tide’ on HIP. Weight reduction interventions targeting high-risk individuals, while beneficial for those individuals, did not significantly impact forecasted HIP incidence rates. The importance of maintaining interventions promoting healthy weight in childhood was demonstrated.
Patient ownership of primary biliary cholangitis long-term management
Authors: Leighton Jessica , Thain Collette , Mitchell-Thain Robert , Dyson Jessica K , Jones David E 
Published: June 2020

ObjectivePatient ownership of disease is vital in rare diseases like primary biliary cholangitis (PBC). This survey of UK members of the PBC foundation aimed to assess patients’ perception of their disease management, focusing on key biomarkers and problematic symptoms.DesignRegistered PBC foundation members were surveyed on their experiences on their most recent clinic visit, covering the type of hospital and clinician and whether biochemical response and symptom burden were discussed, including who initiated these conversations. Respondents were also asked about their willingness to initiate these conversations.ResultsAcross 633 respondents, 42% remembered discussing alkaline phosphatase, the key biochemical response measure, and the majority of discussions were initiated by the healthcare provider. 56% of respondents remembered discussing itch, a key PBC symptom. There was no distinction between the grade of healthcare professional, but both patients and clinicians were significantly more likely to discuss symptoms over disease progression. Reassuringly, 84% of respondents felt willing to initiate conversations about their illness, regardless of the grade of managing clinician.ConclusionsThis work lays a positive foundation for patient education and empowerment projects, likely to improve clinical outcomes. Key aspects of management (biochemical response to treatment and symptom burden) should be emphasised as topics of discussion to both patients and clinicians managing PBC. We suggest a simple cue card to prompt patient-led discussion.
Reductions in bilateral transverse sinus pressure gradients with unilateral transverse venous sinus stenting for idiopathic intracranial hypertension
Authors: Larson Anthony , Rinaldo Lorenzo , Chen John J , Cutsforth-Gregory Jeremy , Theiler Amy R , Brinjikji Waleed 
Published: June 2020

BackgroundVenous sinus stenting is an effective treatment for papilledema associated with idiopathic intracranial hypertension (IIH). It is unclear whether unilateral transverse-sigmoid sinus (TSS) stenting adequately decompresses the contralateral TSS system in cases of bilateral transverse sinus stenosis. The objective of this study was to compare changes in bilateral TSS pressure gradients following unilateral TSS stenting in a series of patients with IIH.MethodsConsecutive patients from a single institution who underwent venous sinus stenting for IIH with measurement of bilateral pressure gradients before and after stenting for IIH were enrolled. Pressure gradients in both TSS pre- and post-stenting were measured during the procedure. The TSS with the highest gradient was stented. Changes in TSS pressure gradients following stent placement were calculated for both TSS. Mean changes in pressure gradients of ipsilateral and contralateral TSS were calculated.ResultsSixteen patients with IIH who underwent TSS stenting were included. All were female. Mean age was 36.4 years. The right-sided TSS was the stented side in 12 (75.0%) patients. The mean pre-stent pressure gradient of the ipsilateral TSS was 19.3 mmHg (SD=10.8), which was reduced to a mean of 3.8 mmHg (3.4) following stent placement (P =<0.0001). On the contralateral (non-stented) side, the mean pre-stent gradient of 15.1 mmHg (7.5) was reduced to a mean of 7.8 mmHg (6.6) following stenting (P=0.006).ConclusionsThe use of a single stent provides some venous decompression of the contralateral non-stented stenosis in most cases of IIH treated with endovascular therapy.
Effects of enhanced STI partner notification counselling and provider-assisted partner services on partner referral and the incidence of STI diagnosis in Cape Town, South Africa: randomised controlled trial
Authors: Mathews Catherine , Lombard Carl , Kalichman Moira , Dewing Sarah , Banas Ellen , Dumile Sekelwa , Mdlikiva Amanda , Mdlikiva Thembinkosi , Jennings Karen Ann , Daniels Johann , Berteler Marcel , Kalichman Seth C 
Published: June 2020

ObjectivesWe investigated the effects of an enhanced partner notification (PN) counselling intervention with the offer of provider-assisted referral among people diagnosed with STI in a Cape Town public clinic.MethodsParticipants were adults diagnosed with STI at a community clinic. After the standard STI consultation, participants were randomly allocated in a 1:1:1 ratio to (1) ‘HE’: 20 min health education; (2) ‘RR’: 45 min risk reduction skills counselling; or (3) ‘ePN’: 45 min enhanced partner notification communication skills counselling and the offer of provider-assisted referral. The primary outcome was the incidence of repeat STI diagnoses during the 12 months after recruitment, and the secondary outcome was participants’ reports 2 weeks after diagnosis of notifying recent partners. Incidence rate ratios (IRRs) were used to compare the incidence rates between arms using a Poisson regression model.ResultsThe sample included 1050 participants, 350 per group, diagnosed with STI between June 2014 and August 2017. We reviewed 1048 (99%) participant records, and identified 136 repeat STI diagnoses in the ePN arm, 138 in the RR arm and 141 in the HE arm. There was no difference in the annual incidence of STI diagnosis between the ePN and HE arms (IRR: 1.0; 95% CI 0.7 to 1.3), or between the RR and HE arms (IRR: 0.9; 95% CI 0.7 to 1.2). There was a greater chance of a partner being notified in the ePN condition compared with the HE condition, 64.3% compared with 53.8%, but no difference between the RR and HE arms.ConclusionsPN counselling and education with provider-assisted services has the potential to change the behaviour of people diagnosed with STIs, increasing the number of partners they notify by more than 10%. However, these changes in behaviour did not lead to a reduction of repeat STI diagnoses.Trial registration numberPACTR201606001682364.
Exclusive and diffractive $$\gamma \gamma $$ production in PbPb collisions at the LHC, HE-LHC and FCC
Authors: Coelho R. O. , Gonçalves V. P. , Martins D. E. , Rangel M. 
Published: May 2020

AbstractIn this paper we present a detailed analysis of the contribution of the Light-by-Light (LbL), Durham and double diffractive processes for the diphoton production in ultraperipheralPbPbcollisions at the Large Hadron Collider (LHC), High-Energy LHC (HE-LHC) and Future Circular Collider (FCC). The acceptance of the central and forward LHC detectors is taken into account and predictions for the invariant mass, rapidity, transverse momentum and acoplanarity distributions are presented. Our results indicate that the contribution of the Durham process is negligible and that the double diffractive process can be strongly suppressed by the exclusivity cuts, which will allow to perform a precise analysis of the LbL scattering, as well the search of beyond Standard Model physics in this final state.
Suppression of the cavity oscillation using high-speed mass injection
Authors: Wang Xiansheng , Yang Dangguo , Zhou Fangqi , Wu Junqiang , Lu Bo 
Published: May 2020

The cavity flow oscillation is a typical unsteady, nonlinear flow phenomenon, accompanied by resonance with strong pressure oscillation and intense turbulence. A control method is proposed to suppress the cavity oscillation using high-speed mass injection. Wind-tunnel experiments are performed to validate the control method. A length-to-depth six cavity is employed in the experiments with a Mach number 1.8 of the incoming flow. The upstream injection is generated in the leading edge of the cavity with a large momentum coefficient (more than 10%). Effects of the high-speed mass injection on the cavity oscillation are validated by a significant reduction of the overall sound pressure level inside the cavity. The broadband cavity noise is reduced by more than 10 dB, with a great suppression of the cavity tones. Owing to the high-speed mass injection, the cavity oscillation has been effectively suppressed in the supersonic condition. Because there is no need of additional gas supply in the control system, the control strategy is considered to be a potential and practical candidate for engineering applications.
Experimental study on the entrainment performance and flow choking phenomenon of a two-stage multi-nozzle ejector
Authors: Chen Pei 
Published: May 2020

A two-stage multi-nozzle ejector experimental system is established, and the pressure distribution on the wall and in the flow field of the test model is measured when the total pressure of the two-stage primary flow changes. Results show that when the total pressure of primary flow increases, vacuum chamber static pressure decreases to its lowest limit of 1 kPa, and then begins to rise. Flow choking mechanism of two stage ejector is clarified. If the total pressure of the first stage primary flow is low, the flow in the second stage ejector first reaches the choking state when the total pressure of the second stage primary flow increases, which causes the rise of first stage back pressure, and then the first stage ejector reaches the choking state. If the total pressure of the first stage primary flow is high, the increase of total pressure of the second stage primary flow reduces the back pressure of the first stage ejector and therefore the first stage ejector first reaches the choking state, and then the second stage reaches the choking state.
A thermally tunable terahertz three-dimensional perfect metamaterial absorber for temperature sensing application
Authors: Zou Haijun , Cheng Yongzhi 
Published: May 2020

We present a three-dimensional (3D) perfect metamaterial absorber (PMA) for temperature sensing application in terahertz region. The PMA consists of a 3D metal resonator structure array and a continuous metal film separated by an indium antimonide (InSb) layer. The numerical simulations demonstrate that the PMA can achieve perfect absorption (about 99.9%) with the high [Formula: see text]-factor of about 18.8 at 2.323 THz when the temperature is 300 K (room temperature). Further simulation results indicate that this terahertz PMA is polarization-insensitive and wide-angle for both transverse electric (TE) and transverse magnetic (TM) waves. The electric field and surface current distributions of the unit-cell structure indicate that the perfect absorption is originated from the excitation of the fundamental magnetic and electric dipole resonance mode. Since the permittivity of the InSb is sensitive to the external temperature, the resonance absorption frequency of the PMA can be dynamically adjusted. The temperature sensitivity of the PMA is about 15.24 GHz/K, which may have potential prospects in temperature sensing and detection.
Challenges in Designing a Fully Autonomous Socially Assistive Robot for People with Parkinson’s Disease
Authors: Wilson Jason R. , Tickle-Degnen Linda , Scheutz Matthias 
Published: June 2020

Assistive robots are becoming an increasingly important application platform for research in robotics, AI, and HRI, as there is a pressing need to develop systems that support the elderly and people with disabilities, with a clear path to market. Yet, what remains unclear is whether current autonomous systems are already up to the task or whether additional HRI work is needed to make these systems acceptable and useful.
In this article, we report our efforts of developing and evaluating an architecture for a fully autonomous robot designed to assist older adults with Parkinson’s disease (PD) in sorting their medications. The main goal for the robot is to aid users in a manner that maintains the autonomy of the user by providing cognitive and social support with varying levels of assistance. We first evaluated the robot with subjects drawn from a pool of university students, which is common practice in experimental work in psychology and HRI. As the results were very positive, we followed up with an evaluation using people with Parkinson’s disease, who surprisingly had mostly negative outcomes. We thus report our analysis of the differences in the evaluations and discuss the challenges for HRI posed by the sources of the negative evaluations: (1) designing a robot to adapt to the many routines the participants use at home, (2) unique needs of participants with PD not present in student participants, and (3) the role of familiar technologies in designing and evaluating a new technology. While it is unlikely, given the current state of technology, that fully autonomous assistive robots for older adults will be available in the near term, we believe that our work exposes a critical need in HRI to involve the target population as early as possible in the design process.
Designing Digital Vertigo Experiences
Authors: Byrne Richard , Marshall Joe , Mueller Florian ‘Floyd’ 
Published: June 2020

Many people enjoy “vertigo” sensations caused by intense playful bodily activities such as spinning in circles, and riding fairground rides. Game scholar Caillois calls such experiences “vertigo play,” elucidating that these enjoyable activities are a result of confusion between sensory channels.
In HCI, designers are often cautious to avoid deliberately causing sensory confusion in players, but we believe there is an opportunity to transition and extend Caillois’ thinking to the digital realm, allowing designers to create novel and intriguing digital bodily experiences inspired by traditional vertigo play activities.
To this end, we present the Digital Vertigo Experience framework. Derived from four case studies and the development of three different digital vertigo experiences, this framework aims to bring the excitement of traditional vertigo play experiences to the digital world, allowing designers to create more engaging and exciting body-based games, and provides players with more possibilities to enjoy novel and exciting play experiences.