bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impaired empathy and increased anger following social exclusion in non-intoxicated opioid users
Authors: Carlyle Molly , Rowley Megan , Stevens Tobias , Karl Anke , Morgan Celia J. A. 
Published: November 2019

Abstract

Rationale
Social functioning is modulated by the endogenous opioid system. In opioid use disorder, social functioning appears disrupted, but little research has delineated the nature of these deficits and their relationship to acute opioid use.

Objectives
The current study aimed to assess both emotional and cognitive empathy, along with subjective and physiological responses to social exclusion in opioid users who were either acutely intoxicated or non-intoxicated from using opioids.

Methods
Individuals on an opioid substitution medication (OSM) were divided into ‘intoxicated users’ (had taken their OSM the same day as testing, n = 20) and ‘non-intoxicated users’ (had taken their OSM > 12 h ago, n = 20) and compared with opioid-naïve controls (n = 24). Empathy was assessed using the multifaceted empathy test and self-report questionnaire. Participants also underwent a period of social exclusion (Cyberball Game) and completed measures of mood and physiological responses (salivary cortisol and heart rate).

Results
Non-intoxicated users had significantly lower emotional empathy (the ability to experience others’ emotions), as well as greater anger after social exclusion when compared with the intoxicated users and controls. Anger did not change with social exclusion in the intoxicated user group and cortisol levels were lower overall.

Conclusions
Reduced ability to spontaneously share the emotions of others was reported in non-intoxicated users, particularly regarding positive emotions. There was some support for the idea of hyperalgesia to social pain, but this was restricted to an enhanced anger response in non-intoxicated users. Equivalent rates of empathy between the intoxicated users and controls could indicate some remediating effects of acute opioids.
Novel approach to passivation of InAs/GaSb type II superlattice photodetectors
Authors: Papis-Polakowska E. , Kaniewski J. , Jasik A. , Czuba K. , Sankowska I. , Karbownik P. , Runka T. , Martyński T. , Makowiecki J. , Łapiński A. 
Published: November 2019

Abstract
The innovative two-step passivation by octadecanethiol (ODT) self-assembled monolayers (SAMs) and the following silicon dioxide (SiO2) deposition was used for the type-II InAs/GaSb superlattice photodetector. To understand the mechanism of passivation, the (100) GaSb surface covered with the ODT and, for comparison, with the biphenyl thiol (BPT), was characterized by the atomic force microscopy, Raman spectroscopy and contact angle analysis. The results of the study indicated the presence of the homogeneous both the ODT and the BPT monolayers; however, the ODT SAMs were more stable. Therefore, the ODT-based wet treatment was used in the two-step passivation resulting in a reduction of the dark current by one order of magnitude for passivated detector compared with an unpassivated device.
How fly neurons compute the direction of visual motion
Authors: Borst Alexander , Haag Jürgen , Mauss Alex S. 
Published: November 2019

AbstractDetecting the direction of image motion is a fundamental component of visual computation, essential for survival of the animal. However, at the level of individual photoreceptors, the direction in which the image is shifting is not explicitly represented. Rather, directional motion information needs to be extracted from the photoreceptor array by comparing the signals of neighboring units over time. The exact nature of this process as implemented in the visual system of the fruit flyDrosophila melanogasterhas been studied in great detail, and much progress has recently been made in determining the neural circuits giving rise to directional motion information. The results reveal the following: (1) motion information is computed in parallel ON and OFF pathways. (2) Within each pathway, T4 (ON) and T5 (OFF) cells are the first neurons to represent the direction of motion. Four subtypes of T4 and T5 cells exist, each sensitive to one of the four cardinal directions. (3) The core process of direction selectivity as implemented on the dendrites of T4 and T5 cells comprises both an enhancement of signals for motion along their preferred direction as well as a suppression of signals for motion along the opposite direction. This combined strategy ensures a high degree of direction selectivity right at the first stage where the direction of motion is computed. (4) At the subsequent processing stage, tangential cells spatially integrate direct excitation from ON and OFF-selective T4 and T5 cells and indirect inhibition from bi-stratified LPi cells activated by neighboring T4/T5 terminals, thus generating flow-field-selective responses.
Celiac disease and complement activation in response to Streptococcus pneumoniae
Authors: Tjernberg Anna Röckert , Woksepp Hanna , Sandholm Kerstin , Johansson Marcus , Dahle Charlotte , Ludvigsson Jonas F , Bonnedahl Jonas , Nilsson Per , Ekdahl Kristina Nilsson 
Published: November 2019

Abstract
Individuals with celiac disease (CD) are at increased risk of invasive pneumococcal disease (IPD). The aim of this study was to explore whether the complement response to Streptococcus pneumoniae differed according to CD status, and could serve as an explanation for the excess risk of IPD in CD. Twenty-two children with CD and 18 controls, born 1999–2008, were included at Kalmar County Hospital, Sweden. The degree of complement activation was evaluated by comparing levels of activation products C3a and sC5b-9 in plasma incubated for 30 min with Streptococcus pneumoniae and in non-incubated plasma. Complement analyses were performed with enzyme-linked immunosorbent assay (ELISA). Pneumococcal stimulation caused a statistically significant increase in C3a as well as sC5b-9 in both children with CD and controls but there was no difference in response between the groups. After incubation, C3a increased on average 4.6 times and sC5b-9 22 times in both the CD and the control group (p = 0.497 and p = 0.724 respectively).
Conclusion: Complement response to Streptococcus pneumoniae seems to be similar in children with and without CD and is thus unlikely to contribute to the increased susceptibility to invasive pneumococcal disease in CD.What is Known:• An excess risk of pneumococcal infections has been demonstrated in individuals with celiac disease.• Infectious complications can depend on hyposplenism but alternative mechanisms are sparsely examined.What is New:• Complement activation in response to Streptococcus pneumoniae was examined in children with and without celiac disease but no differences could be demonstrated.
Value of information in multiple criteria decision making: an application to forest conservation
Authors: Eyvindson Kyle , Hakanen Jussi , Mönkkönen Mikko , Juutinen Artti , Karvanen Juha 
Published: November 2019

Abstract
Developing environmental conservation plans involves assessing trade-offs between the benefits and costs of conservation. The benefits of conservation can be established with ecological inventories or estimated based on previously collected information. Conducting ecological inventories can be costly, and the additional information may not justify these costs. To clarify the value of these inventories, we investigate the multiple criteria value of information associated with the acquisition of improved ecological data. This information can be useful when informing the decision maker to acquire better information. We extend the concept of the value of information to a multiple criteria perspective. We consider value of information for both monetary and biodiversity criteria and do not assume any fixed budget limits. Two illustrative cases are used describe this method of evaluating the multiple criteria value of information. In the first case, we numerically evaluate the multiple criteria value of information for a single forest stand. In the second case, we present a forest planning case with four stands that describes the complex interactions between the decision maker’s preference information and the potential inventory options available. These example cases highlight the importance of examining the trade-offs when making conservation decisions. We provide a definition for the multiple criteria value of information and demonstrate the potential application when conservation issues conflict with monetary issues.
Upgraded bidirectional approach video-assisted neck surgery (BAVANS) using a rigid endoscope with variable viewing direction for advanced endoscopic lymph node dissection in thyroid cancer patients
Authors: Nakajo Akihiro , Minami Koji , Shinden Yoshiaki , Toda Hiroko , Hirashima Tadahiro , Nagata Ayako , Nomoto Yuki , Maemura Kosei , Natsugoe Shoji 
Published: November 2019

Abstract
In 2011, we developed bidirectional approach video-assisted neck surgery (BAVANS) for endoscopic thyroid cancer surgery. BAVANS combines two different approach pathways at 180 degrees to the cervical lesion for endoscopic thyroidectomy and complete cervical lymphadenectomy. We reported previously that the cranio-caudal approach is extremely useful for endoscopic complete lymph node dissection around the trachea. In 2014, we upgraded the initial BAVANS for better maneuverability and quality of lymph node dissection. A new high-tech rigid endoscope with a variable viewing direction (EndoCAMeleon™), has enabled us to reduce the camera port in the anterior neck while keeping the easy maneuverability and the same quality of central lymph node dissection (LND) as with the initial BAVANS. Endoscopic thyroid cancer surgery is now evolving concurrently with new visual technology.
Active control of multiscale features in wall-bounded turbulence
Authors: Cui Xiaotong , Jiang Nan , Zheng Xiaobo , Tang Zhanqi 
Published: November 2019

Abstract
This study experimentally investigates the impact of a single piezoelectric (PZT) actuator on a turbulent boundary layer from a statistical viewpoint. The working conditions of the actuator include a range of frequencies and amplitudes. The streamwise velocity signals in the turbulent boundary layer flow are measured downstream of the actuator using a hot-wire anemometer. The mean velocity profiles and other basic parameters are reported. Spectra results obtained by discrete wavelet decomposition indicate that the PZT vibration primarily influences the near-wall region. The turbulent intensities at different scales suggest that the actuator redistributes the near-wall turbulent energy. The skewness and flatness distributions show that the actuator effectively alters the sweep events and reduces intermittency at smaller scales. Moreover, under the impact of the PZT actuator, the symmetry of vibration scales’ velocity signals is promoted and the structural composition appears in an orderly manner. Probability distribution function results indicate that perturbation causes the fluctuations in vibration scales and smaller scales with high intensity and low intermittency. Based on the flatness factor, the bursting process is also detected. The vibrations reduce the relative intensities of the burst events, indicating that the streamwise vortices in the buffer layer experience direct interference due to the PZT control.
Risk of Depression in the Offspring of Parents with Depression: The Role of Emotion Regulation, Cognitive Style, Parenting and Life Events
Authors: Loechner Johanna , Sfärlea Anca , Starman Kornelija , Oort Frans , Thomsen Laura Asperud , Schulte-Körne Gerd , Platt Belinda 
Published: November 2019

Abstract
Children of depressed parents are at heightened risk for developing depression, yet relatively little is known about the specific mechanisms responsible. Since preventive interventions for this risk group show small effects which diminish overtime, it is crucial to uncover the key risk factors for depression. This study compared various potential mechanisms in children of depressed (high-risk; n = 74) versus non-depressed (low-risk; n = 37) parents and explored mediators of parental depression and risk in offspring. A German sample of N = 111 boys and girls aged 8 to 17 years were compared regarding children’s (i) symptoms of depression and general psychopathology, (ii) emotion regulation strategies, (iii) attributional style, (iv) perceived parenting style and (v) life events. Children in the high-risk group showed significantly more symptoms of depression and general psychopathology, less adaptive emotion regulation strategies, fewer positive life events and fewer positive parenting strategies in comparison with the low-risk group. Group differences in positive and negative attributional style were small and not statistically significant in a MANOVA test. Maladaptive emotion regulation strategies and negative life events were identified as partial mediators of the association between parental depression and children’s risk of depression. The study highlights the elevated risk of depression in children of depressed parents and provides empirical support for existing models of the mechanisms underlying transmission. Interestingly, the high-risk group was characterised by a lack of protective rather than increased vulnerability factors. These results are crucial for developing more effective preventive interventions for this high-risk population.
The life cycle of the Atlantic Beach-Cricket, Pseudomogoplistes vicentae Gorochov, 1996
Authors: Vahed Karim 
Published: November 2019

AbstractThe Atlantic Beach-Cricket,Pseudomogoplistes vicentae, inhabits shingle beaches, with a range that extends from the UK to the Canary Islands. Little is known about the natural history of this species, which is listed by the IUCN as Vulnerable. In the present study, a combination of field sampling (by pitfall trapping and direct searching) in spring, summer, autumn and late winter at two different sites in the UK, together with culturing eggs and nymphs in captivity, was used to determine the life cycle. Eggs laid in August in captivity showed no visible embryonic development until May and hatched the following July. There was no difference in the time taken to hatch between eggs maintained over winter at either 4 or 11 °C. Nymphal instars present in the field indicated that the majority of eggs hatch from June to early August. From October to February in the field, the majority of nymphs were estimated to be at the 7th instar. Development appeared to resume by April and nymphs reached adulthood by July to August in the field, two years after the eggs from which they hatched were likely to have been laid. The number of nymphal instars ranged from 10 to 11 (mode: 11) in males and 11 to 13 (mode: 12) in females. In captivity, most adult males died by the end of November, while 35% of females survived until March. Females preferred to oviposit in driftwood rather than in sand in the laboratory. This fact, together with the early embryonic diapause, suggests that the species might be able to disperse by rafting at the egg stage.
Convergence education—an international perspective
Authors: Herr Daniel J. C. , Akbar Bushra , Brummet Jennifer , Flores Sarah , Gordon Ashley , Gray Brian , Murday James 
Published: November 2019

Abstract
The US National Science Foundation defines convergence as the deep integration of knowledge, techniques, and expertise from multiple fields to form new and expanded frameworks for addressing scientific and societal challenges and opportunities. Because convergence research is progressing at a rapid clip, the quick evolution of non-traditional perspectives that it engenders will present a number of challenges/opportunities to education. NSF, the Organization for Economic Cooperation and Development; the US National Academies of Sciences, Engineering and Medicine; and the University of Southern California sponsored a workshop, with global participation, to explore actions that would facilitate convergence in education. A descriptive of the workshop and the key action items it identified are presented.
How Reflective and Critical Norm-Usage Paves the Way to the Public Power of Judgement
Authors: Cern Karolina M. 
Published: November 2019

Abstract
The purpose of this paper is to demonstrate that Neil MacCormick’s conception of norm-usage makes it necessary to address the concept of the public power of judgement as the key concept for understanding the democratic legitimization of current law. Therefore, firstly I analyse MacCormick’s conception of norm-usage, secondly I demonstrate that it leads to the idea of the institutionalisation of judgemental–interpretative practice, and thirdly, I show that the latter paves the way to the public power of judgement. Finally, I argue that this power needs to be elaborated in terms of competencies which are broader than legal skills and legal reasoning, and, further, that these competencies condition the use of both legal skills and reasoning. Importantly, MacCormick’s contribution to understanding the public power of judgement—when further developed—may indicate the profound role of comprehending the proper significance of law in a democratic polity and its relationship to the citizenry.
Secular trends in adiposity and musculoskeletal dimensions of elite heavyweight boxers between 1889 and 2019
Authors: Han Thang S. , Callis Tracy G. , Sharma Pankaj , Lean Michael E. J. 
Published: November 2019

Abstract

Purpose
With improving nutrition and health, athletes have grown taller and heavier over the past century. Since there is no weight restriction in the heavyweight class, secular changes in anthropometric measurements of heavyweight boxers may mirror those of contemporary general populations.

Objectives
We aimed to (1) examine secular trends in adiposity and musculoskeletal measurements in heavyweight boxers, (2) determine anthropometric differences between champions and unsuccessful challengers.

Methods
Detailed demographics taken at time of contest (first official World Championship to current contest: 1889–2019) were collected from media archives.

Results
All 237 boxers (83 champions, 154 challengers) contesting a recognised heavyweight World Championships were identified. They had mean (± SD) age = 28.9 ± 4.1 years, height = 187.3 ± 6.5 cm, reach = 195.2 ± 9.4 cm, weight = 97.5 ± 11.5 kg, BMI = 27.8 ± 2.4 kg/m2 and waist = 87.9 ± 6.2 cm. Contest years explained 25.9% (p < 0.001) of the variance in BMI for champions and 30.9% (p < 0.001) for challengers, 9.1% (p < 0.071) in WC for champions and 19.9% (p < 0.001) for challengers. Contest years correlated with height (r = 0.531, p < 0.001), reach (r = 0.341, p < 0.001), weight (r = 0.603, p < 0.001) and BMI (r = 0.370, p = 0.001) among all documented boxers, and with waist only in challengers (r = 0.349, p < 0.001) but not in champions (r = 0.078, p = 0.509). Compared with challengers, champions had greater stature by + 3.4 cm (p < 0.001), reach + 3.6 cm (p = 0.005) and weight + 3.7 kg (p = 0.017), with similar BMI and waist. Champions had larger biceps and forearms but did not differ from challengers in other musculoskeletal dimensions.

Conclusions
Over 130 years elite heavyweight boxers have increased in size (BMI) and reach but waists in champions have remained static. Being heavier, taller with longer and bigger arms, but with similar in BMI and waist, appear to be differentiating factors between champions and challengers.
Important Goals, Meanings, and Relationships in Flourishing and Languishing States: Towards Patterns of Well-being
Authors: Wissing Marié P. , Schutte Lusilda , Liversage Christelle , Entwisle Brenda , Gericke Marianne , Keyes Corey 
Published: November 2019

AbstractQualitative studies of lay people’s perspectives on facets of well-being are scarce, and it is not known how the perspectives of people with high and low levels of well-being dovetail or differ. This research explored the experiences of people with high/flourishing versus low/languishing levels of positive mental health in three cross-sectional survey design studies. Languishing and flourishing participants were selected in each study based on quantitative data from the Mental Health Continuum - Short Form as reported by Keyes et al. (Journal of Health and Social Behavior43:207–222, 2002). Qualitative content analyses were conducted on written responses to semistructured open-ended questions on the what and why of important meaningful things (study 1,n = 42), goals (study 2,n = 30), and relationships (study 3,n = 50). Results indicated that well-being is not only a matter of degree—manifestations differ qualitatively in flourishing and languishing states. Similar categories emerged for what flourishing and languishing people found important with regard to meaning, goals, and relationships, but the reasons for the importance thereof differed prominently. Languishing people manifested a self-focus and often motivated responses in terms of own needs and hedonic values such as own happiness, whereas flourishers were more other-focused and motivated responses in terms of eudaimonic values focusing on a greater good. We propose that positive mental health can be conceptualized in terms of dynamic quantitative and qualitativepatterns of well-being.Interventions to promote well-being may need to take into account the patterns of well-being reflecting what people on various levels of well-being experience and value.
Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival
Authors: Tong Dan , Zhang Li , Ning Fei , Xu Ying , Hu Xiaoyu , Shi Yan 
Published: November 2019

Abstract
Common γ chain cytokines are important for immune memory formation. Among them, the role of IL-2 remains to be fully explored. It has been suggested that this cytokine is critically needed in the late phase of primary CD4 T cell activation. Lack of IL-2 at this stage sets for a diminished recall response in subsequent challenges. However, as IL-2 peak production is over at this point, the source and the exact mechanism that promotes its production remain elusive. We report here that resting, previously antigen-stimulated CD4 T cells maintain a minimalist response to dendritic cells after their peak activation in vitro. This subtle activation event may be induced by DCs without overt presence of antigen and appears to be stronger if IL-2 comes from the same dendritic cells. This encounter reactivates a miniature IL-2 production and leads a gene expression profile change in these previously activated CD4 T cells. The CD4 T cells so experienced show enhanced reactivation intensity upon secondary challenges later on. Although mostly relying on in vitro evidence, our work may implicate a subtle programing for CD4 T cell survival after primary activation in vivo.