bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengendalian Tata Ruang di Kota Tasikmalaya
Authors: Rais Abdul Ba'its  
Published: November 2020

Belum maksimalnya upaya kebijakan Pemerintah Kota Tasikmalaya dalam pengendalian penataan tata ruang di Kota Tasikmalaya tentu harus dicarikan akar permasalahannya secara akademis. Langkah awal untuk mengetahui tentang berbagai permasalahan dalam penataan ruang pemanfaatan ruang di Kota Tasikmalaya adalah melakukan studi tentang pengendalian kebijakan. Studi tentang pengendalian tata ruang diharapkan dapat mengetahui tentang berbagai persoalan yang dihadapi dalam mengendalikan, mengawasi dan penerapan kebijakan penataan ruang dari berbagai faktor yang mempengaruhinya. Nampaknya diindikasikan bahwa pengendalian tata ruang dalam pemanfaatan ruang di Kota Tasikmalaya yang dilakukan oleh Dinas Pekerjaan Umum dan Penataan Ruang Kota Tasikmalaya masih menyimpan beberapa permasalahan, diantaranya sebagai berikut: Tujuan penelitian ini adalah untuk mengetahui dan menganalisis pengendalian tata ruang di Kota Tasikmalaya (Studi Dinas Pekerjaan Umum dan Penataan Ruang Kota Tasikmalaya). Metode penelitian yang digunakan adalah adalah metode deskriptif dengan menggunakan pendekatan kualitatif. Pengumpulan data terdiri dari data primer dan data sekunder, dengan teknik pengumpulan data secara teknik pengamatan langsung (Observasi langsung), teknik wawancara mendalam, dan studi dokumentasi. Teknik pemeriksaan data yang digunakan adalah triangulasi sumber. Analisis data dilakukan sejak sebelum memasuki lapangan, selama di lapangan dan setelah selesai di lapangan. Berdasarkan hasil penelitian dan yang telah dilaksanakan dan pembahasan yang telah diuraikan, maka penelitian Pengendalian Tata Ruang di Kota Tasikmalaya.” (Studi Dinas Pekerjaan Umum dan Penataan Ruang Kota Tasikmalaya) kurang optimal, hal tersebut dapat dilihat dari variabel sebagai berikut: Menentukan alat pengukuran (standar) bahwa pengendalian tata ruang dan peraturan zonasi di wilayah Kota Tasikmalaya belum sepenuhnya bisa dikatakan ideal sebagai alat ukur, karena. Konsep perubahan tata ruang tersebut hanya melihat kepentingan Dinas, tidak memperhatikan kepentingan masyarakat lainnya sebagai pengguna fasilitas mereka mengeluhkan mengenai pembangunan yang telah dilakukan Pemerintah Kota Tasikmalaya
REGIONAL CHEMOTHERAPY IN TREATMENT FOR UNRESECTABLE COLORECTAL CANCER METASTASES TO THE LIVER RESISTANT TO SYSTEMIC CHEMOTHERAPY
Authors: Polikarpov Aleksey , Tarazov Pavel , Granov Dmitriy , Kagacheva T. 
Published: November 2020

Aim. To determine the effectiveness of regional chemotherapy (RChT) in the treatment of patients with unresectable colorectal metastases to the liver, resistant to systemic chemotherapy (SChT).
Materials and methods. Between 2011 and 2017, we treated 60 patients with unresectable colorectal metastases to the liver, resistant to SChT from 2011 to 2017 y. All patients received previously 3-35 cycles of SCht which were ineffective in 54 and was discontinued in 6 patients because of grade III-IV toxicity. In all patients, antitumor drugs which were most effective in SChT were used for RChT,. In the absence of effect on any schemes of SChT, monotherapy with the Mitomycinum C was done. Hepatic arterial infusion (HAI) was carried out for hypovascular metastases using 4-6 gr 5-fluorouracil, 15-20 mg mitomycinum C, 150-200 mg oxaliplatinum, 160200 mg irinotecan. Transcatheter arterial chemoembolization (TACE) for hypervascular metastases was performed by selective infusion of suspension of Lipidol with chemotherapeutic drug: mitomycin C 10-20 mg or irinotecan 160-200 mg or doxorubicinum 50-80 mg and followed by arterial occlusion by gelfoam. Combination, TACE+HAI, was performed with difficult anatomical variants of hepatic artery.
Results. We performed 222 cycles of RChT (from 2 to 15, average 6 per patient). There were no complication and lethality. Time to progression after the onset of RChT was 12.4 months in both groups. The median survival from the start of the first cycle SChT was 22 mo in the group with synchronous metastases of colorectal cancer to the liver and 23 mon for metachronic group.
Conclusion. Our preliminary results showed prospect of using RChT in the treatment of patients with chemo-resistant colorectal metastases to the liver.
Optimization Zakat for Sustainable Development Goals: Evidence from Baitul Mal Aceh
Authors: Riyaldi Muhammad Haris , Suriani Suriani , Nurdin Ridwan 
Published: November 2020

Zakat as a wealth distribution mechanism has an impact on reducing poverty as the most important point in achieving the sustainable development goals (SDGs). An important role can be played by zakat institutions in reducing poverty levels, especially zakat institutions in regions in Indonesia. This study aims to explain the mechanism of zakat as an instrument of Islamic economy in order to contribute to the achievement of SDGs in Aceh Province by optimizing the role of the Aceh Baitul Mal. With the grounded research method, this research is carried out by collecting data through interviews with academics of Islamic studies, Islamic boarding school scholars and zakat practitioners who are competent to assess the role of zakat in poverty alleviation in Aceh. The results showed that to achieve the sustainable development goals (SDGs) Baitul Mal Aceh must optimize zakat as a transfer of wealth from muzakki to mustahik, both optimizing the collection and optimizing the distribution of zakat. Optimization of zakat collection is carried out by means of education, socialization, and good zakat services, while optimization of distribution is carried out by prioritizing zakat for poverty alleviation programs, ensuring the accuracy of zakat recipients, and distribution using consumptive and productive methods.
Keywords: zakat collection, zakat distribution, SDGs
New records of six moth (Lepidoptera: Erebidae, Lasiocampidae) species in south African countries, with comments on their distribution
Authors: Delabye Sylvain , Sedláček Ondřej , Maicher Vincent , Tropek Robert 
Published: November 2020

Southern Africa hosts a high diversity of ecosystems and habitats with a tremendous diversity of Lepidoptera. Although it is one of the most studied parts of the Afrotropics, the knowledge on diversity and distribution of south African moth fauna remains insufficient. To partly fill this gap, we surveyed macromoths by automatic light traps in five localities in two relatively less sampled south African countries.
We reported six species and one genus (Remigioides) of moths which had not yet been recorded in Namibia or Zimbabwe. Although none of these records broadened the known distribution of individual species to a new biogeographical region, they still fill important gaps in their distributions. The known distributional ranges of two species have been substantially extended, although they are still within the same biogeographical regions: ca. 800 km southwards for Remigioides remigina (Mabille, 1884) and ca. 600 km westwards for Haplopacha cinerea Aurivillius, 1905.
Des mariages à tout prix ? Genèse, contestation et régulation du marché de la rencontre (1840-1940)
Authors: Gaillard Claire-Lise 
Published: November 2020

Depuis le début du xix e siècle jusqu’à la veille de la Seconde Guerre mondiale, la société française assiste à l’invention d’un marché de la rencontre. L’émergence de ce marché se heurte à une solide contestation morale : les agences matrimoniales sont perçues comme une dangereuse extension des activités marchandes à la sphère intime. L’article entreprend de montrer que cette critique de la marchandisation est profondément paradoxale pour la société du xix e siècle, puisque l’émergence de ce marché ne s’accompagne pas d’une dérégulation des rencontres amoureuses et d’un désencastrement du choix du conjoint au sens où l’entendrait Eva Illouz, mais qu’il s’appuie, au contraire, sur un écosystème du choix du conjoint très largement dominé par les cadres sociaux, économiques et familiaux. Puisque le critère économique est la première règle d’appariement des couples bourgeois, les agences matrimoniales ne sont pas coupables de l’intrication de l’argent avec l’intimité, mais seulement de la rendre visible. Dès lors que cette exhibition nourrit la contestation du marché, elle conduit également marchands et clientèle à élaborer des stratégies diverses pour rendre acceptables aux yeux de la morale autant l’intrication économie/intime que le poids de l’économie dans les critères de choix du conjoint.
Une ration contre un soir au cabaret : pratiques et représentations des « bienfaiteurs » et « sugar daddies » au Burundi
Authors: Courtois Anne-Claire 
Published: November 2020

Cet article propose d’illustrer les pratiques et représentations d’une forme spécifique d’échange économico-sexuel au Burundi, celle des « bienfaiteurs », en la resituant dans la longue durée. Le recours aux « bienfaiteurs » se présente comme une stratégie de subsistance et de survie pour les femmes cheffes de ménage de la capitale. Cette pratique de sexe transactionnel, mise en regard avec celle, plus connue, des « sugar daddies », conforte et révèle un système global de domination masculine et de séniorité.
Une incertaine alliance
Authors: Mélandri Pierre 
Published: November 2020

1973, l’« Année de l’Europe ». 1983, l’« Année des euromissiles ». Les deux dates délimitent une décennie cruciale pour l’Alliance atlanti­que. En 1973, elle tente de s’adapter aux changements profonds inter­venus depuis sa création. Mais doit-elle le taire selon la vision de Henry Kissinger ou celle de Michel Jobert ? Le débat est à peine entamé que le premier « choc » pétrolier détourne les démocraties vers d’autres prio­rités. Renforcée par l’esquisse d’une coopération trilatérale, leur solida­rité n’en est pas moins ébranlée par le retour des problèmes militaires et par leurs divergences sur la détente. Aussi, loin de les rapprocher, l’invasion de l’Afghanistan tend-elle plutôt à les diviser. En 1983, les grandes querelles se sont un peu apaisées et les Pershing-II et les mis­siles de croisière américaine ont pu être déployés. Mais rien n’est vrai­ment réglé. Et l’histoire de l’Occident est encore dominée par toutes sor­tes d’incertitudes (sur le leadership d’une Amérique en déclin relatif, sur la place de l’Allemagne, sur la stratégie atomique) apparues ou renfor­cées au cours de ces dix années.

Fondé sur le dépouillement des principales sources disponibles et sur plusieurs dizaines d’interviews (dont une grande partie réalisée lors d’un séjour, en juillet 1983, au Wilson Center de Washington), cet ouvrage recourt à une approche historique pour éclairer l’actualité.
Le port de New York et le commerce extérieur américain
Authors: Heffer Jean 
Published: November 2020

Pendant la guerre de Sécession, le port de New York a atteint son apogée relatif dans le commerce extérieur américain. Cependant la fin de ces conditions exceptionnelles ne marque pas le retour au statu quo car, désormais, jusqu’à la fin du XIXe siècle, le roi-coton doit partager sa couronne avec les céréales. Si New York maintient son hégémonie aux importations, il voit sa suprématie contestée aux exportations, principalement de grains, par ses riveaux les plus proches, Boston, Philadelphie et Baltimore. L’objet de cet ouvrage est l’analyse de la rivalité entre ports pour la domination du commerce des États-Unis, à un moment où ce pays devient le grenier de l’Europe industrielle. Une fois établis les faits, est proposée une gamme d’interprétations, qui s’appuient sur des modèles partiels ou sur les arguments avancés par les contemporains, afin de jeter quelques lumières sur la hiérarchie des causes.
PRMT1 Modulates Processing of Asthma-Related Primary MicroRNAs (Pri-miRNAs) into Mature miRNAs in Lung Epithelial Cells
Authors: Zhai Weiqi , Sun Haoming , Li Zhi , Li Li , Jin Ai , Li Yuwen , Chen Jian , Yang Xiaojun , Sun Qingzhu , Lu Shemin , Roth Michael 
Published: November 2020

Abstract
Protein arginine methyltransferase-1 (PRMT1) is an important epigenetic regulator of cell function and contributes to inflammation and remodeling in asthma in a cell type–specific manner. Disease-specific expression patterns of microRNAs (miRNA) are associated with chronic inflammatory lung diseases, including asthma. The de novo synthesis of miRNA depends on the transcription of primary miRNA (pri-miRNA) transcript. This study assessed the role of PRMT1 on pri-miRNA to mature miRNA process in lung epithelial cells. Human airway epithelial cells, BEAS-2B, were transfected with the PRMT1 expression plasmid pcDNA3.1-PRMT1 for 48 h. Expression profiles of miRNA were determined by small RNA deep sequencing. Comparing these miRNAs with datasets of microarrays from five asthma patients (Gene Expression Omnibus dataset), 12 miRNAs were identified that related to PRMT1 overexpression and to asthma. The overexpression or knockdown of PRMT1 modulated the expression of the asthma-related miRNAs and their pri-miRNAs. Coimmunoprecipitation showed that PRMT1 formed a complex with STAT1 or RUNX1 and thus acted as a coactivator, stimulating the transcription of pri-miRNAs. Stimulation with TGF-β1 promoted the interaction of PRMT1 with STAT1 or RUNX1, thereby upregulating the transcription of two miRNAs: let-7i and miR-423. Subsequent chromatin immunoprecipitation assays revealed that the binding of the PRMT1/STAT1 or PRMT1/RUNX1 coactivators to primary let-7i (pri-let-7i) and primary miR (pri-miR) 423 promoter was critical for pri-let-7i and pri-miR-423 transcription. This study describes a novel role of PRMT1 as a coactivator for STAT1 or RUNX1, which is essential for the transcription of pri-let-7i and pri-miR-423 in epithelial cells and might be relevant to epithelium dysfunction in asthma.
A Whole Blood Enzyme-Linked Immunospot Assay for Functional Immune Endotyping of Septic Patients
Authors: Mazer Monty B , C. Caldwell Charles , Hanson Jodi , Mannion Daniel , Turnbull Isaiah R , Drewry Anne , Osborne Dale , Walton Andrew , Blood Tessa , Moldawer Lyle L , Brakenridge Scott , Remy Kenneth E , Hotchkiss Richard S 
Published: November 2020

Abstract
Sepsis initiates simultaneous pro- and anti-inflammatory processes, the pattern and intensity of which vary over time. The inability to evaluate the immune status of patients with sepsis in a rapid and quantifiable manner has undoubtedly been a major reason for the failure of many therapeutic trials. Although there has been considerable effort to immunophenotype septic patients, these methods have often not accurately assessed the functional state of host immunity, lack dynamic range, and are more reflective of molecular processes rather than host immunity. In contrast, ELISpot assay measures the number and intensity of cytokine-secreting cells and has excellent dynamic range with rapid turnaround. We investigated the ability of a (to our knowledge) novel whole blood ELISpot assay and compared it with a more traditional ELISpot assay using PBMCs in sepsis. IFN-γ and TNF-α ELISpot assays on whole blood and PBMCs were undertaken in control, critically ill nonseptic, and septic patients. Whole blood ELISpot was easy to perform, and results were generally comparable to PBMC-based ELISpot. However, the whole blood ELISpot assay revealed that nonmonocyte, myeloid populations are a significant source of ex vivo TNF-α production. Septic patients who died had early, profound, and sustained suppression of innate and adaptive immunity. A cohort of septic patients had increased cytokine production compared with controls consistent with either an appropriate or excessive immune response. IL-7 restored ex vivo IFN-γ production in septic patients. The whole blood ELISpot assay offers a significant advance in the ability to immunophenotype patients with sepsis and to guide potential new immunotherapies.
Il servizio di bioetica dell’azienda ospedaliera di Padova: un’esperienza italiana di consulenza e formazione etico-clinica
Authors: Benciolini P. , Pegoraro R. , Cadelli F. 
Published: November 2020

L’articolo presenta il Servizio di Bioetica dell’Azienda Ospedaliera di Padova collocandolo nel contesto internazionale della consulenza etico-clinica, della quale fornisce un quadro generale e sintetico.
La consulenza etico-clinica, sviluppatasi soprattutto nel Nord America a partire dalla fine degli anni Sessanta, può essere definita come un servizio fornito da un consulente singolo, da un team o da un comitato avente come oggetto le questioni etiche coinvolte in uno specifico caso clinico.
La storia della consulenza etico-clinica è strettamente connessa con quella dei Comitati Etici Ospedalieri, anche nel senso che essa costituisce in parte un tentativo di superamento di alcuni limiti ravvisati in tale forma di comitati e di ridefinizione delle loro funzioni. In quest’ottica, alcuni propongono la presenza, negli ospedali, sia di servizi di consulenza che di comitati, con ruoli complementari focalizzati rispettivamente sulla consulenza e sull’elaborazione di linee guida, e con ruoli formativi distinti.
Il Servizio di Bioetica di Padova, che è attivo dal settembre 1996, è unico nel suo genere in Italia, soprattutto con riferimento al fatto di non riportare ad un comitato etico. Le sue finalità principali sono: consulenza etica sui casi clinici rivolta agli operatori sanitari; formazione etica degli operatori sanitari; elaborazione di linee guida in collaborazione con i comitati etici presenti nel contesto sanitario padovano; definizione di un progetto per la costituzione di un Comitato etico dell’Azienda.
L’attività del Servizio di Bioetica ha finora interessato le funzioni di consulenza e formazione, volutamente scelte come prioritarie, ed il bilancio è positivo sotto entrambi i profili.
Cost and Treatment Characteristics of Sport-Related Knee Injuries Managed by Athletic Trainers: A Report From the Athletic Training Practice-Based Research Network
Authors: Lam Kenneth C. , Marshall Ashley N. , Welch Bacon Cailee E. , Valovich McLeod Tamara C. 
Published: November 2020

Context
Knee injuries are common during sport participation. However, little is known about the overall management and estimated direct costs of care associated with these injuries when under the care of athletic trainers.

Objective
To describe the treatment characteristics and direct costs of care for athletic training services provided for patients with knee injuries.

Design
Descriptive study.

Setting
Ninety-five athletic training facilities across 24 states.

Patients or Other Participants
A total of 117 athletic trainers (females = 56.4%, age = 29.4 ± 8.7 years, years certified = 4.7 ± 6.0, years employed at site = 1.6 ± 4.1).

Main Outcome Measure(s)
Complete patient cases were identified using International Classification of Disease-10 diagnostic codes between 2009 and 2020. Summary statistics were calculated for patient demographics, treatment characteristics, and direct costs of care. Treatment characteristics included the type of athletic training service, duration, amount (eg, number of visits), and direct costs of care.

Results
A total of 441 patient cases were included. The most common injuries reported were cruciate ligament sprain (18.1%, n = 80), medial collateral ligament sprain (15.4%, n = 68), and knee pain (14.1%, n = 62). Injuries occurred most frequently during football (35.4%, n = 156), basketball (14.7%, n = 65), and soccer (12.7%, n = 56). A total of 8484 athletic training services were recorded over 4254 visits, with therapeutic exercise (29.8%, n = 2530), hot or cold pack (25.8%, n = 2189), and therapeutic activities (11.2%, n = 954) being the most frequently reported services. The median duration of care was 23 days and number of visits was 8. The median total cost of care was $564 per injury and $73 per visit.

Conclusions
Patients with knee injuries demonstrated greater time loss than those with other lower extremity injuries. Thus, it is unsurprising that knee injuries were associated with a longer duration and higher cost of care than other lower extremity injuries such as ankle sprains. Future researchers should examine the effectiveness of common treatment strategies and aim to identify treatments that can reduce costs and improve patient outcomes.
Influencia de variables meteorológicas sobre el rendimiento de la caña de azúcar
Authors: Sieiro Miranda Grethel L. , González Hidalgo Maribel , Lozano Rodríguez Miguel A. , Raya Cruz Blanca E. , González Salas Miguel Á. , Aguirre López Enrique 
Published: November 2020

Se seleccionaron 14 ingenios azucareros pertenecientes a las provincias Artemisa, Mayabeque y Matanzas, con sus respectivas estaciones meteorológicas asociadas. Los datos anuales de rendimiento agrícola e industrial de la caña de azúcar y los registros diarios de precipitaciones y temperaturas en el período comprendido entre 1980 y 2011 (30 años), sirvieron de base para el estudio. El análisis de los datos arrojó que en todo el período, la temperatura máxima (Tmáx) no experimentó cambios, la temperatura media (Tm) aumentó en 0,93ºC, mientras que la temperatura mínima (Tmín) lo hizo en 0,62ºC y la amplitud térmica (AT) se redujo en 0,72ºC. De todas las regiones estudiadas, la estación meteorológica de Bahía Honda fue la que mostró los menores valores de AT. Las precipitaciones incrementaron en 33,78%, mientras que RA disminuyó en 52,83% con relación a su valor inicial. Se encontró una dependencia inversa entre la AT y la Tmín, mientras que hubo una fuerte dependencia entre RI y Prec (97%) en las tres provincias. Estas últimas, 10 días antes de la cosecha, tuvieron un ligero efecto negativo sobre RI, en tanto que, éste no fue prácticamente afectado. Se concluyó que la provincia Matanzas fue la que presentó las mejores condiciones climáticas para el cultivo de la caña de azúcar y dentro de ella, la zona más propicia para su desarrollo fue el municipio Jovellanos.
Revisión de las técnicas para el modelado de la distribución de las especies
Authors: Becerra López Jorge Luis , Romero Méndez Ulises , Ramírez Bautista Aurelio , Becerra López Jesús Salvador 
Published: November 2020

En los últimos años se ha generalizado una nueva herramienta que permite analizar objetivamente los patrones espaciales de presencia de organismos: los modelos de distribución de especies. Estos modelos se basan en procedimientos estadísticos y cartográficos que a partir de datos reales de presencia permiten inferir zonas potencialmente idóneas en función de sus características ambientales. Los datos de colecciones de historia natural pueden ser utilizados para este fin adquiriendo así una nueva utilidad. En este trabajo se hace una revisión sobre la variedad de métodos utilizables, sus potencialidades e inconvenientes y los factores limitantes que influyen en la interpretación de los modelos de distribución.