bluuebunny/crossref_metadata_2025_split huggingface dataset:
An artificial intelligence framework for automatic segmentation and volumetry of vestibular schwannomas from contrast-enhanced T1-weighted and high-resolution T2-weighted MRI
Authors: Shapey Jonathan , Wang Guotai , Dorent Reuben , Dimitriadis Alexis , Li Wenqi , Paddick Ian , Kitchen Neil , Bisdas Sotirios , Saeed Shakeel R. , Ourselin Sebastien , Bradford Robert , Vercauteren Tom 
Published: December 2019

OBJECTIVEAutomatic segmentation of vestibular schwannomas (VSs) from MRI could significantly improve clinical workflow and assist in patient management. Accurate tumor segmentation and volumetric measurements provide the best indicators to detect subtle VS growth, but current techniques are labor intensive and dedicated software is not readily available within the clinical setting. The authors aim to develop a novel artificial intelligence (AI) framework to be embedded in the clinical routine for automatic delineation and volumetry of VS.METHODSImaging data (contrast-enhanced T1-weighted [ceT1] and high-resolution T2-weighted [hrT2] MR images) from all patients meeting the study’s inclusion/exclusion criteria who had a single sporadic VS treated with Gamma Knife stereotactic radiosurgery were used to create a model. The authors developed a novel AI framework based on a 2.5D convolutional neural network (CNN) to exploit the different in-plane and through-plane resolutions encountered in standard clinical imaging protocols. They used a computational attention module to enable the CNN to focus on the small VS target and propose a supervision on the attention map for more accurate segmentation. The manually segmented target tumor volume (also tested for interobserver variability) was used as the ground truth for training and evaluation of the CNN. We quantitatively measured the Dice score, average symmetric surface distance (ASSD), and relative volume error (RVE) of the automatic segmentation results in comparison to manual segmentations to assess the model’s accuracy.RESULTSImaging data from all eligible patients (n = 243) were randomly split into 3 nonoverlapping groups for training (n = 177), hyperparameter tuning (n = 20), and testing (n = 46). Dice, ASSD, and RVE scores were measured on the testing set for the respective input data types as follows: ceT1 93.43%, 0.203 mm, 6.96%; hrT2 88.25%, 0.416 mm, 9.77%; combined ceT1/hrT2 93.68%, 0.199 mm, 7.03%. Given a margin of 5% for the Dice score, the automated method was shown to achieve statistically equivalent performance in comparison to an annotator using ceT1 images alone (p = 4e−13) and combined ceT1/hrT2 images (p = 7e−18) as inputs.CONCLUSIONSThe authors developed a robust AI framework for automatically delineating and calculating VS tumor volume and have achieved excellent results, equivalent to those achieved by an independent human annotator. This promising AI technology has the potential to improve the management of patients with VS and potentially other brain tumors.
Patterns of care for ruptured aneurysms of the middle cerebral artery: analysis of a Swiss national database (Swiss SOS)
Authors: Maldaner Nicolai , Steinsiepe Valentin K. , Goldberg Johannes , Fung Christian , Bervini David , May Adrien , Bijlenga Philippe , Schaller Karl , Roethlisberger Michel , Zumofen Daniel W. , D’Alonzo Donato , Marbacher Serge , Fandino Javier , Maduri Rodolfo , Daniel Roy Thomas , Burkhardt Jan-Karl , Chiappini Alessio , Robert Thomas , Schatlo Bawarjan , Seule Martin A. , Weyerbrock Astrid , Regli Luca , Stienen Martin Nikolaus , _ _ 
Published: December 2019

OBJECTIVEThe objective of this study was to determine patterns of care and outcomes in ruptured intracranial aneurysms (IAs) of the middle cerebral artery (MCA) in a contemporary national cohort.METHODSThe authors conducted a retrospective analysis of prospective data from a nationwide multicenter registry of all aneurysmal subarachnoid hemorrhage (aSAH) cases admitted to a tertiary care neurosurgical department in Switzerland in the years 2009–2015 (Swiss Study on Aneurysmal Subarachnoid Hemorrhage [Swiss SOS]). Patterns of care and outcomes at discharge and the 1-year follow-up in MCA aneurysm (MCAA) patients were analyzed and compared with those in a control group of patients with IAs in locations other than the MCA (non-MCAA patients). Independent predictors of a favorable outcome (modified Rankin Scale score ≤ 3) were identified, and their effect size was determined.RESULTSAmong 1866 consecutive aSAH patients, 413 (22.1%) harbored an MCAA. These MCAA patients presented with higher World Federation of Neurosurgical Societies grades (p = 0.007), showed a higher rate of concomitant intracerebral hemorrhage (ICH; 41.9% vs 16.7%, p < 0.001), and experienced delayed cerebral ischemia (DCI) more frequently (38.9% vs 29.4%, p = 0.001) than non-MCAA patients. After adjustment for confounders, patients with MCAA were as likely as non-MCAA patients to experience DCI (aOR 1.04, 95% CI 0.74–1.45, p = 0.830). Surgical treatment was the dominant treatment modality in MCAA patients and at a significantly higher rate than in non-MCAA patients (81.7% vs 36.7%, p < 0.001). An MCAA location was a strong independent predictor of surgical treatment (aOR 8.49, 95% CI 5.89–12.25, p < 0.001), despite statistical adjustment for variables traditionally associated with surgical treatment, such as (space-occupying) ICH (aOR 1.73, 95% CI 1.23–2.45, p = 0.002). Even though MCAA patients were less likely to die during the acute hospitalization (aOR 0.52, 0.30–0.91, p = 0.022), their rate of a favorable outcome was lower at discharge than that in non-MCAA patients (55.7% vs 63.7%, p = 0.003). At the 1-year follow-up, 68.5% and 69.6% of MCAA and non-MCAA patients, respectively, had a favorable outcome (p = 0.676).CONCLUSIONSMicrosurgical occlusion remains the predominant treatment choice for about 80% of ruptured MCAAs in a European industrialized country. Although patients with MCAAs presented with worse admission grades and greater rates of concomitant ICH, in-hospital mortality was lower and long-term disability was comparable to those in patients with non-MCAA.
Fluorescein-guided removal of peripheral nerve sheath tumors: a preliminary analysis of 20 cases
Authors: Vetrano Ignazio G. , Acerbi Francesco , Falco Jacopo , Devigili Grazia , Rinaldo Sara , Messina Giuseppe , Prada Francesco , D’Ammando Antonio , Nazzi Vittoria 
Published: December 2019

OBJECTIVEBenign peripheral nerve sheath tumors (PNSTs) include mainly schwannomas—the most common tumors arising from peripheral nerves—and neurofibromas. Due to their origin, distinguishing between functional intact nerve and the fibers from whence the PNST arose may not always be easy to perform. The introduction of intraoperative tools to better visualize these tumors could be helpful in achieving a gross-total resection. In this study, the authors present a series of patients harboring PNST in which the surgery was performed under fluorescein guidance.METHODSBetween September 2018 and February 2019, 20 consecutive patients with a total of 25 suspected PNSTs underwent fluorescein-guided surgery performed under microscopic view with a dedicated filter integrated into the surgical microscope (YELLOW 560) and with intraoperative monitoring. All patients presented with a different degree of contrast enhancement at preoperative MRI. Fluorescein was intravenously injected after intubation at a dose of 1 mg/kg. Preoperative clinical and radiological data, intraoperative fluorescein characteristics, and postoperative neurological and radiological outcomes were collected and analyzed.RESULTSSix patients were affected by neurofibromatosis or schwannomatosis. There were 14 schwannomas, 8 neurofibromas, 1 myxoma, 1 reactive follicular hyperplasia, and 1 giant cell tumor of tendon sheath. No patient experienced worsening of neurological status after surgery. No side effects related to fluorescein injection were found in this series. Fluorescein allowed an optimal intraoperative distinction between tumor and surrounding nerves in 13 of 14 schwannomas and in all neurofibromas. In 6 neurofibromas and in 1 schwannoma, the final YELLOW 560 visualization showed the presence of small tumor remnants that were not visible under white-light illumination and that could be removed, obtaining a gross-total resection.CONCLUSIONSFluorescein was demonstrated to be a feasible, safe, and helpful intraoperative adjunct to better identify and distinguish PNSTs from intact functional nerves, with a possible impact on tumor resection, particularly in diffuse neurofibromas.
ORTAÖĞRETİMDE GÖREV YAPAN ÖĞRETMENLERİN SINIF YÖNETİMİ KAYGI DÜZEYLERİNİN İNCELENMESİ
Authors: SADIK Fatma , NASIRCI Hasan 
Published: December 2019

Öğretmenlerin sınıf yönetimi açısından temel görevi, olumlu bir öğrenme ortamı oluşturma ve öğretimin etkili olmasını sağlamaktır. Ancak günlük hayatta karşılaşılan güç ilişkileri çoğu zaman sınıf ortamında da kendini gösterebilmekte, bu durum gerek deneyimli gerekse mesleğinin ilk yıllarında olan öğretmenlerin sınıf yönetimi konusunda kaygılanmasına neden olabilmektedir. Bu araştırmanın amacı ortaöğretim kurumlarında çalışan öğretmenlerin sınıf yönetiminde yaşadıkları kaygı düzeyini belirleyerek, bazı değişkenler açısından incelemektir. Araştırmaya 2017-2018 eğitim-öğretim döneminde Adana’daki merkez ilçelerde bulunan liselerde çalışan öğretmenlerden 187’si gönüllü olarak katılmıştır. Verilerin toplanmasında “Kişisel Bilgi Formu” ve “Sınıf Yönetimi Kaygı Ölçeği” kullanılmış, verilerin analizinde Mann Whitney-U ve Kruskal Wallis testleri kullanılmıştır. Araştırmanın sonucunda öğretmenlerin sınıf yönetimi konusunda kaygı düzeylerinin genel olarak düşük olduğu saptanmış, erkek öğretmenlerin kaygı düzeylerinin nispeten daha yüksek düzeyde olduğu görülmüştür. Ulaşılan sonuçlara göre meslek liselerinde meslek derslerine giren ve mevcudu daha az olan sınıflarda çalışan öğretmenlerin sınıf yönetimi kaygı düzeyi daha yüksektir.
Becoming Balinese Islam: Bale Banjar and Subak in Islamic Village of Segara Katon, Karangasem, Bali.
Authors: Segara I Nyoman Yoga 
Published: December 2019

Muslims in Karangasem are relatively homogeneous since they originate from the Sasak tribe, Lombok. The story of the conquest of the kingdom in Lombok by the Kingdom of Karangasem turned out to be the beginning of the Sasak tribe Muslims occupying 25 of the 26 Islamic villages, except the Saren Javanese Islamic Village from Demak, Java. The pattern of settlement through the Islamic Village further spreads around the Kingdom of Karangasem. Sasak tribe Muslims were then currently placed in the catu land which belonged to the kingdom. One of the numerous fascinating Muslim villages is Segara Katon. Some of its residents are still of Balinese origin as the result of the marriage of converted Gamongan people to Segara Katon women. Another uniqueness is the existence of the bale banjar which even though it has been acknowledged as a form of acculturation between Hinduism and Islam in the past, yet, it has been left standing although its function has presently begun to shift along with the establishment of the Nurul Jihad Mosque. The long history and traditions that they experienced in a relatively long time were made a fabulous social capital to survive in the midst of various changes, including being active and creative in strengthening peaceful relations with Hindus through multiple local wisdom. To be able to explore data and analyze how Balinese Muslim people in Segara Katon see themselves and their social world, field research was carried out through interviews, observation, and document studies.
Representation of the Context of Petik Laut (Sea-Picked) Traditions in the Macapat Mursada Text
Authors: Ummah Khothibhatul , Suryadi Suryadi 
Published: December 2019

This article aims to analyze a series of Petik Laut traditions that are the background for the emergence of the Mursada song text. Culture that is continuously carried out will form a tradition. One of the traditions found in Indonesia is the tradition of Petik Laut carried out in Muncar. Another term for the sea quotation is charity marine coastal communities. In its implementation, the Petik Laut tradition has several series of events that must be carried out. The series of events became the background for the emergence of the Mursadasong text that was read when one day before the core event was held. This research is a qualitative descriptive study. The main data source is a series of Petik Laut traditions and tembang macapat texts. The provision of data is obtained by observation-participation techniques, interviews, and document analysis. The data were analyzed using linguistic anthropological theory to find out how the context of the tradition of seas was based on the emergence of the text of the Mursadasong in the Muncar fishing community. The results showed that the context of the sea-picking tradition behind the emergence of the text of the Mursadasong was the opening, the macapatan, the ider bumiand the release of offerings, and the pilgrimage of the grave.
Communication Behaviour of Street Children and Beggars in Makassar
Authors: Bahfiarti Tuti 
Published: December 2019

The purpose of this reseach is to explore, and categorize verbal and non verbal communication behavior in the performances of street children and beggars in Makassar. This study explored the operational actions and motivations of street children and beggars who work the streets. This study uses a qualitative method that seeks to interpret the meaning of data to understand a community's social life. The ethnographic approach to communication studies focuses on studying the interactions and activities of individuals as social creatures in using verbal and non-verbal symbols. Primary data collection was carried out through in-depth interviews with 21 street children informants and beggars operating in three sectors, namely, the Panakukang/ Fly Over/Red Light Sector, the Losari Beach Platform Sector, and the Hertasning Sector. Non-participant observation by repeatedly observing themselves both verbally and non-verbally in performing actions and actions in front of benefactors. This study found verbal and non verbal communication behaviors that are displayed as a form of impression management on the front stage in attracting the sympathies of benefactors. Verbal communication behavior in the form of spoken and written language based on categorical finding verbal symbols of street children and beggars using three elements, namely the structure of the message, the style of the message, and the attractiveness of the message. Furthermore, the categorization of non-verbal communication behaviors is facial expressions, body movements (kinetic), physical appearance (body and manner of dress), and paralinguistic(vocalic).
Exploring Male-Female Dynamics in Muslim Society: A Review of Mernissi’s Beyond the Veil (Revised Edition)
Authors: Al Isra Andi Batara 
Published: December 2019

This is a review of Mernissi’s Beyond the Veil, one of the most influential book discussing Islam and gender.I have to admit that I have not read Mernissi before I take a course called Anthropology and World Religions focusing in Islam in the University of Auckland. Later I know that the reason why her name rarely echoed in anthropological atmosphere in Indonesia (particularly in Sulawesi) is because Mernissi only well-known in gender studies (especially in Islam) and Islamic studies. I know it because the only colleague who knows Mernissi is my professor who studied anthropology and gender (and Islam). Beyond the Veil is an interesting book. It explores the relation and the dynamics within male-female Muslims which even I, as a Muslim, have not realised it before. Excluding the introduction (with three different versions) and the conclusion, Beyond the Veil is divided into two parts. Part one consist of three chapters which are more theoretic (or conceptual) background of the book and I think, it would be easier for the readers to understand the context and to grasp Mernissi’s arguments briefly. Part two consist of six chapters which are more ethnographic oriented (fieldwork-based) since it tells the readers about the dynamics between men and women in modern Morocco (as a case or sample of modern Islamic society).
PEMBERDAYAAN PEREMPUAN BALI DALAM MEMBUAT UPAKARA DI BANJAR GEMEH
Authors: Novia Indriani Made 
Published: December 2019

Perempuan di Bali dituntut banyak menguasai hal yang berkaitan dengan prosesi ritual, persembahyangan, adat dan budaya serta prosesi upacara adat sesuai tata cara Hindu. Salah satu yang wajib perempuan Hindu di Bali kuasai adalah mejejaitan, yang merupakan tahapan kegiatan dalam membuat upakara banten. Upakara atau banten tersebut sebagai sarana untuk berhubungan/mendekatkan diri dengan Ida Sang Hyang Widhi Wasa/manifestasi-Nya yang akan dihadirkan dalam ritual persembahyangan. Pemberdayaan perempuan Bali dalam membuat upakara di Br. Gemeh ini, juga mampu mewujudkan fungsi-fungsi banjar adat baik di bidang agama, adat, budaya, sosial dan ekonomi.
Zaleya decandra exerts anti-cancer activity in HCT-116 cancer cells by impairing mitochondrial activity
Authors: Deivasigamani Malarvizhi , Chandrasekar Ajay Kasivishwanathan , Muthusami Sridhar , Kanniappan Gopalakrishnan Velliyur , Lakshmanan Hariprasath 
Published: December 2019

An attempt has been made to investigate the role of Zaleya decandra on the survival of HCT colon cancer cells in vitro. The cell viability and apoptosis were assessed using MTT assay and acridine orange/ethidium bromide staining, respectively. Mitrochondrial membrane permeability was assessed using rhodamine-123 staining. The activities of caspases were evaluated using ELISA kits. Treatment with Z. decandra extract increased the production of ROS in HCT cells and impaired the mitochondrial activity as evidenced by decreased reduction of tetrazolium salt and enhanced mitochondrial membrane permeability. The onset of apoptosis was evident in cells treated with the extact in acridine orange/ethidium bromide staining and was associated with elevated levels of initiator and effector caspases in the conditioned medium. In conclusion, Z. decandra treatment promoted the apoptosis of HCT colon cancer cells.
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Evaluasi Program Indonesia Pintar Pada Dinas Pendidikan Dan Kebudayaan Kota Baubau Tahun 2017
Authors: Zahimu Hartini 
Published: December 2019

Penelitian ini bertujuan untuk mengetahui evaluasi Program Indonesia Pintar di lingkup Dinas Pendidikan dan Kebudayaan Kota Baubau tahun 2017 dan untuk mengetahui apakah ada hambatan yang ditemukan dalam pelaksanaan programIndonesia Pintar pada Dinas Pendidikan dan Kebudayaan Kota Baubau tahun 2017. Populasi dalam penelitian ini adalah Penerima Program Indonesia Pintar tahun 2017, sedangkan Sampel yang digunakan pada penelitian ini yaitu data pada instansi Dinas Pendidikan dan Kebudayaan Kota Baubau tahun 2017, Jenis data Data Kuantitatif dan Data kualitatif, yaitu Analisis yang digunakan pada penelitian ini adalah Analisis Deskriptif Kualitatif. (3) Berdasarkan hasil penelitian bahwa pelaksanaan Program Indonesia Pintar pada Dinas Pendidikan dan Kebudayaan Kota Baubau tahun 2017, terdapat 9.413 penerima PIP, terdapat sebanyak 8.456 telah tersalurkan, serta sebanyak 957 penerima PIP yang dana nya dikembalikan ke pusat (Pemerintah Pusat) dikarenakan telah meninggal dunia, sudah tidak aktif di Sekolah dan siswa/siswi tersebut telah pindah sekolah.
Pentingnya Pojok ASI Bagi Pekerja Buruh Pabrik Di Kecamatan Bergas Kabupaten Semarang
Authors: Diah L Moneca , Aliviani P Risma , Lestari Puji 
Published: December 2019

Air Susu Ibu (ASI) merupakan makanan bayi dengan standar emas. Sebagian besar ibu di Bergas terutama di Desa Ngempon bekerja sebagai buruh pabrik. Ibu yang bekerja pabrik dan sedang dalam proses menyusui ada 60 orang. Sebagian besar ibu jarang berhasil memberikan ASI Eksklusif karena kendala pekerjaan dan waktu serta ketidaktahuan tentang pentingnya Pojok ASI di tempat kerja. Tujuan kegiatan pengabdian masyarakat meningkatkan pengetahuan dan sikap ibu yang sedang dalam proses menyusui dan bekerja sebagai buruh pabrik tentang pentingnya pojok ASI. Metode pelaksanaan dengan cara penyuluhan (ceramah dan demonstrasi). Penyuluhan di lakukan 2 tahap dengan melalukan pre dan post penyuluhan menggunakan kuesioner.Hasil yang di dapatkan yaitu pengetahuan dan sikap ibu tentang pentingnya pojok ASI sebelum penyuluhan masih rendah. Sebelum dilakukan penyuluhan pengetahuan ibu sebagian besar dengan kategori kurang yaitu 36 ibu (60%). Setelah di lakukan penyuluhan dalam kategori pengetahuan baik sebanyak 40 ibu ( 66,67 %). Sikap ibu tentang pentingnya pojok ASI sebelum di lakukan penyuluhan dalam kategori tidak mendukung yaitu sebanyak 38 ibu ( 63,33% ), sedangkan setelah di lakukan dalam kategori mendukung tentang pentingnya pojok ASI di tempat kerja sebanyak 47 ibu ( 78,33 % ). Hal ini menunjukkan ada peningkatan pengetahuan dan perubahan sikap ibu tentang pentingnya pojok ASI di tempat kerja setelah di lakukan penyuluhan. Ibu di harapkan lebih meningkatkan pengetahuan tentang pentingnya pojok ASI sehingga dapat memanfaatkan pojok ASI dengan baik. Untuk Bidan Desa harus memberikan penyuluhan pada ibu setelah melahirkan tentang pentingnya pojok ASI terutama pada ibu bekerja.
IbM Hidup Sehat Dan Cantik Tanpa Narkoba Dan Kosmetika Berbahaya Di Desa Nyatnyono Ungaran
Authors: Laila Vifta Rissa , Yuswantina Richa , Sunnah Istianatus 
Published: December 2019

Penggunaan narkoba, dewasa ini telah meluas sampai pada kalangan keluarga. Hal ini disebabkan oleh adanya distribusi narkoba pada kalangan ibu rumah tangga, siswa sekolah baik dari SD maupun mahasiswa Perguruan Tinggi.. Parameter kecantikan sampai saat ini, dinilai dari kulit wajah yang putih, halus dan mulus. Beberapa kaum wanita menggunakan produk kosmetika untuk menunjang penampilannya. Kosmetika yang sering kali digunakan antara lain : krim antiaging, bleaching (pemutih wajah), hand body, krim tabir surya. Produk - produk kecantikan yang digunakan tersebut sering kali diperoleh dari distributor yang tidak resmi. Beberapa produk kosmetik yang ditawarkan kadang tidak memiliki izin edar dari BPOM. Akibat yang sering kali ditimbulkan oleh pemakaian kosmetika yang tidak terdaftar, antara lain dapat memberikan efek yang cepat (dalam hitungan hari) tetapi efek jangka lama menyebabkan terjadinya iritasi, kehitaman pada kulit maupun kanker kulit. Edukasi perlu diberikan kepada para bu rumah tangga, remaja putri maupun anggota karang taruna guna peningkatan pengetahuan tentang narkoba maupun kosmetika berbahaya sehingga dapat mengurangi ancaman penggunaan narkoba dan resiko kanker kulit akibat kosmetika berbahaya.