bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extensão universitária: Hanseníase na escola, em busca de um diagnóstico precoce
Authors: Maia Maria Ambrosina Cardoso , Silva Bruna Adriane Andrade , Silva Rafael Chagas 
Published: April 2020

O projeto de extensão teve como objetivo desenvolver atividades educativas sobre hanseníase, visando o esclarecimento sobre sinais da doença e possível detecção de casos novos, de forma a avaliar a situação da hanseníase na população do ensino fundamental do município de Passos-MG. Foram selecionadas intencionalmente 10 escolas públicas com ensino fundamental da área urbana do município de Passos-MG no ano de 2018. Inicialmente realizou-se palestras aos discentes e docentes para inteirá-los a respeito da hanseníase e de seu tratamento. Em um segundo momento, por meio de uma triagem, selecionou-se os alunos que possuíam lesões de pele pigmentadas pelo corpo. Esses alunos, após autorização dos pais, foram convidados a realizar o exame dermatoneurológico e, aqueles com análise sugestiva para hanseníase, encaminhados à Estratégia de Saúde da Família. Participaram das palestras 329 docentes e 2.962 discentes, sendo que 305 discentes foram submetidos ao exame dermatoneurológico. Desses, seis casos foram sugestivos para hanseníase e encaminhados para a Estratégia de Saúde da Família. Notou-se grande desconhecimento por parte da população a respeito da doença, principalmente em relação à cura. A busca ativa de casos é um método importante para o controle da hanseníase.
Palavras-chave: Hanseníase; Doença Infectocontagiosa; Relações Comunidade-Instituição

Health students' perceptions on interdisciplinary work: experience at the outreach project smile on duty
Abstract: The objective of the extension project was to develop educational activities about leprosy, aiming at the clarification of the disease symptoms and possible detection of new cases, to assess the leprosy scenario among elementary school students in the city of Passos, Minas Gerais state. Ten public elementary schools in the urban area of Passos were selected intentionally in 2018. Initially, lectures were held to students and teachers in order to brief them about leprosy and its treatment. At a second stage, students who had pigmented skin lesions on their bodies were selected through a screening. These students, after parental consent, were invited to undergo an exam dermato-neurological, and those with a suggestive analysis for leprosy were referred to the Family Health Strategy program. A total of 329 teachers and 2,962 students attended the lectures, and of these students, 305 underwent the exam dermato-neurological. Six cases were indicative of leprosy and committed to the Strategy of Family Health program. There was a significant lack of knowledge on the part of the population about the disease, mainly concerning the cure. Thus, active searching for cases is an essential method for leprosy control. demands, promoting their potential to work collectively and answer to the current demands of interdisciplinary healthcare.
Keywords: Leprosy; Communicable Diseases; Community-Institutional Relations
<b>Book Review of <i>Dancing with Disaster: Environmental Histories, Narratives, and Ethics for Perilous Times</i></b> // Reseña de <i>Dancing with Disaster: Environmental Histories, Narratives, and Ethics for Perilous Times</i>
Authors: Fibisan Veronica 
Published: April 2020

Book review of Kate Rigby's Dancing with Disaster: Environmental Histories, Narratives, and Ethics for Perilous Times.Resumen Reseña de Dancing with Disaster: Environmental Histories, Narratives, and Ethics for Perilous Times de Kate Rigby.
Наш современник в зеркале рекламы
Authors: Yudina A.D. 
Published: April 2020

В статье говорится о языковых изменениях, которые произошли в рекламе за последние годы. Автор обращает внимание на заимствованные слова, расширение круга лексической сочетаемости некоторых используемых в рекламе слов, активное употребление местоимений, обращение к именам предшественников, языковые игры для привлечения потенциальных потребителей рекламируемых товаров и услуг.The article talks about the changes that have occurred in advertising in recent years. The author draws attention to the excessive fascination of contemporaries with borrowed words, to the expansion of the lexical compatibility of some words used in advertising, on active use of pronouns, on indifference of contemporaries to names of great predecessors and on language games for attraction of potential consumers of the advertised goods and services.
PENERAPAN PENGATURAN PEMBUANGAN LIMBAH MINYAK KE LAUT OLEH KAPAL TANKER DILIHAT DARI PERSPEKTIF HUKUM LINGKUNGAN DI INDONESIA
Authors: Permata W Diah Okta , Gusmayanti Irma , Sari Ria Maya 
Published: April 2020

AbstrakPencemaran lingkungan laut karena minyak bumi umumnya bersumber dari kapal tanker, baik yang berasal dari tangki bahan bakar kapal itu sendiri atau minyak kotor yang terdapat di dalam kamar mesin maupun minyak sebagai kargo (muatan). Pencemaran laut dapat berdampak sangat luas terhadap segala kehidupan baik di laut maupun daratan yang terkena pencemaran, sehingga adanya pemikiran siapa yang akan memberikan ganti rugi apabila terjadi pencemaran laut perlu diatur secara jelas. Pengaturan mengenai tanggung jawab pencemaran laut bagi kapal-kapal yang mengangkut minyak sebagai muatan (tanker) terdapat dalam Civil Liability Convention 1969. Upaya pencegahan dan penanggulangan pencemaran laut telah dilakukan oleh Indonesia dengan meratifikasi beberapa konvensi internasional seperti Civil Liability Convention 1969. Bagi Negara peserta Civil Liability Convention 1969, langkah-langkah yuridis yang perlu disiapkan adalah menyusun dan menetapkan ketentuan peraturan nasional di bidang pencemaran lingkungan laut dan/atau perairan di sekitarnya, dalam hal ini ketentuan peraturan oleh masing-masing Negara peserta disesuaikan dengan kebutuhannya dengan berpegang atau berpedoman pada tatanan hukum internasional yang berlaku. AbstractThe marine environmental pollution due to oil are generally sourced from the tanker, both derived from the fuel tank of the vessels itself or dirty oil inside engine compartment and oil as cargo. Marine environmental pollution can impact very broadly against all life either in the sea or land affected by the pollution, so any thought of who would provide compensation in the event of marine environmental pollution needs to be clearly regulated. The regulation of marine environmental pollution liability for vessels that carry oil as cargo (tanker) are regulated in Civil Liability Convention 1969 (CLC 1969). The Preventions and controls of marine pollution have been made by Indonesia to ratify several international Conventions such as Civil Liability Convention 1969. For the member states of Civil Liability Convention 1969, juridical measures that need to be prepared is to compose and establish national regulations in the field of marine environmental pollution and/or the surrounding waters, in the provisions of regulation by each the member states needs to be adjusted to hold or guided by existing international legal order.
PERAN HUKUM DI INDONESIA DALAM PENANGGULANGAN DAMPAK PERUBAHAN IKLIM
Authors: Amelina Fitri 
Published: April 2020

AbstrakPerubahan iklim telah menjadi permasalahan global yang memberikan dampak pasti dan tidak terelakan lagi di tingkat regional maupun internasional. Meningginya permukaan air laut, mencairnya es di kutub, sampai kerugian ekonomi di wilayah Pasifik sebagaimana dilansir oleh Asian Development Bank di tahun 2013. Meningkatnya pemanasan global dan produksi gas rumah kaca memberikan ancaman tersendiri untuk pembangunan berkelanjutan. Adanya komitmen warga dunia dalam menjalin kerja sama guna menekan produksi gas rumah kaca dan menanggulangi dampak perubahan iklim dapat dilihat dari beberapa instrumen internasional terkait hal tersebut yang secara bertahap telah dihasilkan dan diemplementasikan. Adanya kerja sama dari negara-negara maju sebagai penyumbang gas emisi terbanyak dengan negara-negara berkembang seharusnya mampu menghasilkan kolaborasi yang cukup baik dalam upaya penanganan dampak perubahan iklim. Indonesia, dalam hal ini sesuai dengan prinsip common but differentiated responsibilities turut serta dalam upaya penanganan perubahan iklim dengan ratifikasi perjanjian internasional, implementasi melalui satuan petugas khusus di bidang perubahan iklim, dan penegakan hukum dalam upaya melestarikan lingkungan. AbstractClimate change has become a global problem and has certain and uninevitable impacts globally or internationally. Sea level rising, ice melting in the pole or even economic damages in Pacific region released by 2013 Asian Development Bank. Increasing of global warming and greenhouse gasses production provide a separate threat to sustainable development. The commitment of the worldwide community to cooperate in order to reduce the production of greenhouse gasses and mitigate the impact of climate change could be seen from several international instruments related to it has gradually produced and implemented. The cooperation of the developed countries as the largest contributor to the emissions and developing countries should be able to produce a pretty good collaboration in efforts to address climate change impacts. Indonesia, in this case in accordance with the principle of common but differentiated responsibilities to participate in efforts to address climate change with the ratification of international treaties, the implementation through a special unit of officers in the field of climate change, and law enforcement in an effort to preserve the environment.
Numerical Modeling of Suprathermal Electron Transport in the Solar Wind: Effects of Whistler Turbulence
Authors: Tang Bofeng , Zank Gary P. , Kolobov Vladimir I. 
Published: April 2020

Abstract
The solar wind electron velocity distribution function deviates significantly from an equilibrium Maxwellian distribution and is composed of a Maxwellian core, a suprathermal halo, a field-aligned component strahl, and a higher-energy superhalo. Wave–particle interactions associated with whistler wave turbulence are introduced into the kinetic transport equation to describe the interaction between the suprathermal electrons and the whistler waves and to explain the observation that the halo and the strahl relative densities vary in an opposite sense. An efficient numerical method has been developed to solve the Fokker–Planck kinetic transport equation. Application of the numerical method to suprathermal electrons in the solar wind in the presence of whistler waves is presented. Comparison and analysis between the numerical results and observations are made.
An Accurate, Extensive, and Practical Line List of Methane for the HITEMP Database
Authors: Hargreaves Robert J. , Gordon Iouli E. , Rey Michael , Nikitin Andrei V. , Tyuterev Vladimir G. , Kochanov Roman V. , Rothman Laurence S. 
Published: April 2020

Abstract
A methane line list for the HITEMP spectroscopic database, covering 0–13,400 cm−1 (>746 nm), is presented. To create this compilation, ab initio line lists of 12CH4 from Rey et al. ApJ, 847, 105 (provided at separate temperatures in the TheoReTS information system), are now combined with HITRAN2016 methane data to produce a single line list suitable for high-temperature line-by-line calculations up to 2000 K. An effective-temperature interpolation model was created in order to represent continuum-like features over the temperature range of study. This model is advantageous to previously used approaches that employ so-called “super-lines,” which are suitable only at a given temperature and require separate line lists for different temperatures. The resultant HITEMP line list contains ∼32 million lines and is significantly more flexible than alternative line lists of methane, while accuracy required for astrophysical or combustion applications is retained. Comparisons against experimental observations of methane absorption at high temperatures have been used to demonstrate the accuracy of the new work. The line list includes both strong lines and quasi-continuum features and is provided in the common user-friendly HITRAN/HITEMP format, making it the most practical methane line list for radiative-transfer modeling at high-temperature conditions.
Pharmacotherapy and other aspects of senior medical students’ knowledge in community-acquired pneumonia: the final results of the KNOCAP II project
Authors: Bontsevich Roman A. , Gavrilova Anna A. , Adonina Anna V. , Vovk Yana R. , Goncharova Natalya Y. , Batisheva Galina A. , Cherenkova Olga V. , Myronenko Olena V. , Luchinina Elena V. , Barysheva Valeriya O. , Ketova Galina G. , Bochanova Elena N. , Tilekeeva Ulankul M. , Dauletbekov Nurbek D. 
Published: April 2020

Introduction: Community-acquired pneumonia (CAP) remains an extensive medical and social problem. It is the most common human disease and one of the leading causes of death from infectious diseases. Increasing the level of senior medical students’ knowledge of the diagnosis, treatment and prevention of CAP will improve the level of medical care to the population.
The aim of the study: to determine the level of senior medical students’ basic knowledge of CAP prevention, diagnosis and treatment with the help of a pharmacoepidemiological study.
Materials and methods: The multicenter study “KNOCAP” (the full name of the project “The Assessment of Phy­sicians’ and Students’ Knowledge of Community-acquired Pneumonia Basics”) presents the results of an anonymous prospective survey aimed at assessing the knowledge and preferences of senior medical students in terms of the CAP pharmacotherapy. In the second stage of the project (2017–2019). The results from 394 senior students from 8 centers of Russia, Ukraine and Kyrgyzstan were received and analyzed. An original questionnaire was developed for this study on the basis of the current clinical guidelines.
Conclusion: The final results of a prospective survey revealed an insufficient level of students’ basic knowledge of diag­nosis, treatment and prevention of CAP. The study revealed a statistically significant heterogeneity of knowledge levels in different centers, which indicates the need for the introduction of unified and in-depth training programs in this area.
Pilot Study of the Juvenile Dermatomyositis Consensus Treatment Plans: A CARRA Registry Study
Authors: Liu Kuan , Tomlinson George , Reed Ann M. , Huber Adam M. , Saarela Olli , Bout-Tabaku Sharon M. , Curran Megan , Dvergsten Jeffrey A. , Eberhard Barbara A. , Jung Lawrence K. , Kim Susan , Ringold Sarah , Rouster-Steven Kelly A. , Tesher Melissa , Wahezi Dawn M. , Feldman Brian M. 
Published: April 2020

Objectives.To determine the feasibility of comparing the Childhood Arthritis and Rheumatology ResearchAlliance (CARRA) consensus treatment plans (CTP) in treating moderate new-onset juvenile dermatomyositis (JDM) using the CARRA registry, and to establish appropriate analytic methods to control for confounding by indication and missing data.Methods.A pilot cohort of 39 patients with JDM from the CARRA registry was studied. Patients were assigned by the treating physician, considering patient/family preferences, to 1 of 3 CTP: methotrexate (MTX) and prednisone (MP); intravenous (IV) methylprednisolone, MTX, and prednisone (MMP); or IV methylprednisolone, MTX, prednisone, and IV immunoglobulin (MMPI). The primary outcome was the proportion of patients achieving moderate improvement at 6 months under each CTP. Statistical methods including multiple imputation and inverse probability of treatment weighting were used to handle missing data and confounding by indication.Results.Patients received MP (n = 13), MMP (n = 18) and MMPI (n = 8). Patients in all CTP had significant improvement in disease activity. Of the 36 patients who remained in our pilot study at 6 months, 16 (44%) of them successfully achieved moderate improvement at 6 months (6/13, 46% for MP; 7/15, 47% for MMP; 3/8, 38% for MMPI). After correcting for confounding, there were no statistically significant pairwise differences between the CTP (P= 0.328–0.88).Conclusion.We gained valuable experience and insight from our pilot study that can be used to guide the design and analysis of comparative effectiveness studies using the CARRA registry CTP approach. Our analytical methods can be adopted for future comparative effectiveness studies and applied to other rare disease observational studies.
Tumor Necrosis Factor Inhibitor Monotherapy Versus Combination Therapy for the Treatment of Psoriatic Arthritis: Combined Analysis of European Biologics Databases
Authors: Thomas Matthew L. , Shaddick Gavin , Charlton Rachel , Cavill Charlotte , Holland Richard , Iannone Florenzo , Lapadula Giovanni , Lopriore Simona , Závada Jakub , Uher Michal , Pavelka Karel , Szczuková Lenka , Sidiropoulos Prodromos , Flouri Irini , Drosos Alexandros , Möller Burkhard , Nissen Michael J. , Müller Rüdiger B. , Scherer Almut , McHugh Neil , Nightingale Alison 
Published: April 2020

Objective.To investigate whether tumor necrosis factor inhibitor (TNFi) combination therapy with conventional synthetic disease-modifying antirheumatic drugs (csDMARD) is more effective for psoriatic arthritis (PsA) and/or improves TNFi drug survival compared to TNFi monotherapy.Methods.Five PsA biologics cohorts were investigated between 2000 and 2015: the ATTRA registry (Czech Republic); the Swiss Clinical Quality Management PsA registry; the Hellenic Registry of Biologics Therapies (Greece); the University of Bari PsA biologics database (Italy); and the Bath PsA cohort (UK). Drug persistence was analyzed using Kaplan-Meier and equality of survival using log-rank tests. Comparative effectiveness was investigated using logistic regression with propensity scores. Separate analyses were performed on (1) the combined Italian/Swiss cohorts for change in rate of Disease Activity Score in 28 joints (DAS28); and (2) the combined Italian, Swiss, and Bath cohorts for change in rate of Health Assessment Questionnaire (HAQ).Results.In total, 2294 patients were eligible for the drug survival analysis. In the Swiss (P= 0.002), Greek (P= 0.021), and Bath (P= 0.014) databases, patients starting TNFi in combination with methotrexate had longer drug survival compared to monotherapy, while in Italy the monotherapy group persisted longer (P= 0.030). In eligible patients from the combined Italian/Swiss dataset (n = 1056), there was no significant difference between treatment arms in rate of change of DAS28. Similarly, when also including the Bath cohort (n = 1205), there was no significant difference in rate of change of HAQ.Conclusion.Combination therapy of a TNFi with a csDMARD does not appear to affect improvement of disease activity or HAQ versus TNFi monotherapy, but it may improve TNFi drug survival.
Utility of the Brief Illness Perception Questionnaire to Monitor Patient Beliefs in Systemic Vasculitis
Authors: Schwartz Mollie N. , Rimland Casey A. , Quinn Kaitlin A. , Ferrada Marcela A. , Gribbons K. Bates , Rosenblum Joel S. , Goodspeed Wendy , Novakovich Elaine , Grayson Peter C. 
Published: April 2020

ObjectiveTo assess the validity and clinical utility of the Brief Illness Perception Questionnaire (BIPQ) to measure illness perceptions in multiple forms of vasculitis.MethodsPatients with giant cell arteritis (GCA), Takayasu arteritis (TA), antineutrophil cytoplasmic antibody–associated vasculitis (AAV), and relapsing polychondritis (RP) were recruited into a prospective, observational cohort. Patients independently completed the BIPQ, Multidimensional Fatigue Inventory (MFI), Medical Outcomes Study 36-item Short Form survey (SF-36), and a patient global assessment (PtGA) at successive study visits. Physicians concurrently completed a physician global assessment (PGA) form. Illness perceptions, as assessed by the BIPQ, were compared to responses from the full-length Revised Illness Perception Questionnaire (IPQ-R) and to other clinical outcome measures.ResultsThere were 196 patients (GCA = 47, TA = 47, RP = 56, AAV = 46) evaluated over 454 visits. Illness perception scores in each domain were comparable between the BIPQ and IPQ-R (3.28 vs 3.47,P= 0.22). Illness perceptions differed by type of vasculitis, with the highest perceived psychological burden of disease in RP. The BIPQ was significantly associated with all other patient-reported outcome measures (rho = |0.50–0.70|,P< 0.0001), but did not correlate with PGA (rho = 0.13,P= 0.13). A change in the BIPQ composite score of ≥ 7 over successive visits was associated with concomitant change in the PtGA. Change in the MFI and BIPQ scores significantly correlated over time (rho = 0.38,P= 0.0008).ConclusionThe BIPQ is an accurate and valid assessment tool to measure and monitor illness perceptions in patients with vasculitis. Use of the BIPQ as an outcome measure in clinical trials may provide complementary information to physician-based assessments.
Clinical Characteristics of Acne Fulminans Associated With Chronic Nonbacterial Osteomyelitis in Pediatric Patients
Authors: Meinzer Ulrich , See Helene , Bader-Meunier Brigitte , Juillard Caroline , Duquesne Agnes , Melki Isabelle , Faye Albert , Bourrat Emmanuelle 
Published: April 2020

ObjectiveAcne fulminans (AF) is a rare, explosive systemic form of acne. Chronic nonbacterial osteomyelitis (CNO) or chronic recurrent multifocal osteomyelitis (CRMO) is a primarily pediatric autoinflammatory disorder characterized by sterile osteolytic bone lesions. Concomitant occurrence of CNO/CRMO and AF is very rare, and little is known about the epidemiological and clinical particularities of this association. The aim of this retrospective observational study was to describe the characteristics of pediatric patients with CNO/CRMO associated to AF.MethodsElectronic mailing lists of French medical societies were used to call for patients with CNO/CRMO and AF. A search for published patients with CNO/CRMO and AF was performed by screening PubMed.ResultsWe identified 5 original patients and 10 patients from the literature. All patients were adolescent boys. Mean age at disease onset was 14.8 years. Nine of 15 patients had received isotretinoin before the sudden onset of AF. Osteoarticular symptoms appeared within < 1–3 months after the onset of AF. The mean numbers of clinical and radiological bone lesions were 3.6 and 5.6, respectively. The percentages of patients with involvement of vertebrae, pelvis, chest, and cranial were 40%, 40%, 33.3%, and 6.6%, respectively. Arthritis was observed in 69.2% of patients and sacroiliac arthritis in 46.2%.ConclusionCNO/CRMO associated to AF occurs predominantly in male adolescents and is characterized by frequent involvement of the axial skeleton and arthritis. Epidemiological and clinical features of these patients differ from general CNO/CRMO cohorts. Clinical management requires careful handling of isotretinoin doses.