bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of Home Delivery among Women Aged 15-24 Years in Tanzania
Authors: Kimario Florence F. , Festo Charles , Shabani Josephine , Mrisho Mwifadhi 
Published: April 2020

Background: The United Nation’s Sustainable Development Goal number 3 aims at reducing the maternal mortality rate by less than 70/100,000 live births globally and 216/100,000 live births in developing regions by 2030. Despite several interventions in Tanzania, maternal mortality has increased from 454/100,000 live births in 2010 to 556/100,000 live births in 2015. Home delivery and maternal young age contribute to maternal deaths. Reducing home deliveries among women aged 15-24 years may likely decrease the prevalence of maternal deaths in Tanzania. This study investigated the determinants of home delivery among women aged 15- 24 years in rural and mainland districts of Tanzania.
Methods: This study uses a mixed-methods approach using data collected as part of the evaluation of government and UNICEF interventions in 13 districts of Tanzania mainland from October and November 2011. Results from the secondary analysis were supplemented by qualitative data collected between February and April 2019 from four rural districts: Bagamoyo, Tandahimba, Magu, and Moshi.
Results: A total of 409 adolescents and young women who delivered one year before the quantitative data collection were included in the final analysis. A quarter of them gave birth at home. Having at least four antenatal care (ANC) visits (OR=0.23, 95% CI: 0.12-0.41, p<0.01), planning place of delivery (OR=0.22, 95%CI: 0.14-0.36 p<0.01), and knowledge of the danger signs during pregnancy (OR=0.36, 95% CI: 0.22- 0.57, p<0.01) were significantly associated with the place of delivery.
Conclusion and Global Health Implications: Maternal level of education, number of ANC visits attended, planned place of delivery, and knowledge of danger signs during pregnancy were the determinants of the choice of place of delivery among women aged 15-24 years in Tanzania. Understanding these risk factors is important in designing programs and interventions to reduce maternal deaths from women of this age group which contributes about 18% of all maternal deaths in Tanzania.
Key words: • Adolescents • Young women • Home delivery • Tanzania • Sub-Saharan Africa

Copyright © 2020 Kimario et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Variability in Groundwater Flow and Chemistry in the Houzhai Karst Basin, Guizhou Province, China
Authors: Barna Joshua M. , Fryar Alan E. , Cao Le , Currens Benjamin J. , Peng Tao , Zhu Chen 
Published: April 2020

ABSTRACT
Understanding how karst aquifers store and transmit water and contaminants is an ongoing problem in hydrogeology. Multiple flow paths and recharge heterogeneity contribute to the complexity of these systems. This study explored karst-conduit connectivity and water-chemistry variability within the Houzhai catchment in Guizhou Province, China. Artificial tracer tests were conducted during both the monsoon and dry seasons to understand temporal variability in connectivity and water velocity between karst features. Multiple flow paths through the catchment were activated during the monsoon season and partially abandoned during the dry season. Additionally, gradient reversals during monsoonal high-flow events and as a result of pumping were observed. Synoptic water samples from several karst features taken during both monsoon and dry seasons elucidated spatial and temporal variability within the catchment. Water residence time was generally longer during the dry season, and flow within the Houzhai catchment was determined to be temporally dependent. Time-series sampling at the outlet spring following a monsoonal storm event captured chemical variability and identified multiple flow paths. Overall, this study refines widely applicable methods for studying karst systems to this catchment and provides a foundation for future studies in similar settings.
Identificación de las capacidades tecnológicas y de investigación de la Escuela de Suboficiales y Nivel Ejecutivo Gonzalo Jiménez de Quesada
Authors: Parra-Bernal León Darío , Argote-Cusi Milenka Linneth , Montoya-Parraga Lucy Alcira , Martinez-Rozo Nelly 
Published: April 2020

Rev.esc.adm.neg
En el plan nacional de desarrollo «prosperidad para todos» en sus capítulos VII y VIII se resaltó la importancia de fortalecer el sistema nacional de ciencia y tecnología, a partir de la articulación entre la Universidad, el Estado y el sector productivo. Para que dicha articulación surta efecto, se hace necesario el fortalecimiento de capacidades institucionales de transferencia de resultados de investigación, que sirvan como puentes facilitadores entre las necesidades de la sociedad y el sector privado y público, y la oferta de productos en ciencia y tecnología emanada de cada universidad, que pueda dar solución total o parcial a dichas necesidades.
Pensando en ello, el proyecto del cual surge este artículo tuvo como propósito caracterizar el estado actual del proceso de transferencia de resultados de investigación y gestión del conocimiento, que ha realizado la escuela de suboficiales de la policía, Gonzalo Jiménez de Quesada, como un caso de estudio que documenta la metodología utilizada para mapear las capacidades de transferencia y gestión del conocimiento en una organización. De acuerdo con lo anterior, uno de los principales hallazgos de la investigación fue identificar cuáles serían los principales cuellos de botella para mejorar el proceso de desarrollo y maduración de los proyectos y productos de investigación, susceptibles de ser transferidos al sector público. Se observó que el mayor obstáculo a superar es la continuidad de los proyectos o iniciativas, bajo nivel de divulgación de las mismas, falta de capacitación y el desarrollo de tutoriales para la implementación de estos.
Participation of adults with cognitive, physical, or psychiatric impairments in family of origin and intimate relationships: a grounded theory study
Authors: Pfister Andreas , Georgi-Tscherry Pia , Berger Fabian , Studer Michaela 
Published: April 2020

Abstract
Background: How adults with disabilities perceive participation has received little attention. Our purpose was to formulate a grounded theory on participation, based on the subjective experience of adults with cognitive, physical, or psychiatric impairment(s), and to identify barriers, facilitators, and support needs concerning participation in different areas of life. We aimed to explore whether the United Nations’ Convention on the Rights of Persons with Disabilities (CRPD), ratified by Switzerland in 2014, and its principles are being met. Here we report on the main category and focus on the participation areas ‘family of origin’ and ‘intimate relationships.’ Methods: In a qualitative, grounded theory study, we conducted problem-centered interviews with 23 adults with cognitive, physical, or psychiatric impairments (30­-53 years; 11 men, 12 women), with different housing (on their own, assisted living, with parents) and work situations (primary vs. secondary labor market) in nine German-speaking Swiss cantons. Results: Participation can be understood as a continuum that extends on a horizontal level (from participation is restricted to participation takes place) and a vertical level (separative setting vs. inclusive setting). In separative as well as in inclusive settings, diverse levels of participation are possible. Many participants were stuck in an ‘in-between’ area between separative and inclusion-oriented settings. In the family of origin, there was a thin line between fulfilling relations that enhance participation and conflictual relations and overprotective parenting that limit participation. In intimate relationships, opportunities for participation were limited overall. Many interviewees were single. Social environment and family of origin (e.g., parents) can enable and facilitate intimate relationships and sexual contacts but can also be an important barrier.Conclusions: Participation can be understood as a continuum. Participation restrictions exist in separative as well as in inclusive-oriented settings, also in the areas of family of origin and intimate relationships. Participation barriers must be torn down in separative as well as in inclusion-oriented settings. Trajectories to inclusive settings should be facilitated. Families with children with impairment(s) should be supported from early on to create the best possible participation possibilities for the (adult) person with impairment(s) and to support the family of origin itself.
Peripheral Non-enzymatic Antioxidants in Patients with Schizophrenia：A Case-control Study
Authors: Lu Zhe , Wen Tianyang , Wang Yingtan , Kan Weijing , Xun Guanglei 
Published: April 2020

Abstract
Background: Recent studies show that oxidative stress is associated with the pathogenesis of schizophrenia. There are two major types of antioxidant systems in vivo, namely enzymatic antioxidants and non-enzymatic antioxidants. This study investigated differences of non-enzymatic antioxidants between schizophrenia patients and healthy controls. Methods: Peripheral UA, ALB, and TBIL of 107 schizophrenic patients in the acute stage and 101 in the remission stage were measured respectively, so were 273 healthy controls. Results: The levels of UA ( P =0.020) and TBIL ( P <0.001) of schizophrenic patients in acute stage were higher than those of healthy controls, while the level of ALB ( P <0.001) was lower. Similar results were detected form schizophrenic patients in the remission stage. Schizophrenic patients in acute stage were divided into antipsychotics-use subgroup (n=56) and antipsychotics-naïve/free subgroup (n=51). The level of UA ( P =0.001) in the antipsychotics-use subgroup was higher than that in the antipsychotics-naïve/free subgroup, while the level of TBIL ( P =0.002) was lower than that in antipsychotics-naïve/free subgroup. 77 schizophrenic patients in the acute stage were followed up, and there was no significant difference in the level of UA before and after treatment, but levels of ALB ( P <0.001) and TBIL ( P <0.001) decreased significantly after the treatment. Conclusion: This study demonstrated that the dysfunction of the peripheral non-enzymatic anti-oxidation system might be involved in the pathogenesis of schizophrenia.
The Role of Complement Immune Response on Artemisinin Combination Therapy in a Population from Malaria Endemic Region of Western Kenya
Authors: Wanjala Christine , Bergmann-Leitner Elke , Akala Hoseah M , Odhiambo Geoffrey , Ogutu Bernhards R , Andagalu Ben , Kamau Edwin , Ochiel Daniel 
Published: April 2020

Abstract
Background Naturally acquired immunity (NAI), which is characterized by protection against overt clinical disease and high parasitaemia, is acquired with age and transmission intensity. The role of NAI on the efficacy of anti-malarial drugs, including artemisinin-based combinations used as the first-line treatment for uncomplicated Plasmodium falciparum, has not been fully demonstrated. This study investigated the role of NAI in response to artemisinin-based combination therapy (ACT), in symptomatic patients living in western Kenya, a high malaria transmission area. Methods Sera samples from malaria immune participants (n = 105) in a therapeutic efficacy study were assessed for in vitro growth inhibitory activity against the 3D7 strain of P. falciparum using a fluorescent-based growth inhibition assay (GIA). Participants’ age and parasite clearance parameters were used in the analysis. Pooled sera from malaria naïve participants (n = 6) with no Plasmodium infection from malaria non-endemic regions of Kenya was used as negative control.Results The key observations of the study were as follows: (1) Sera with intact complement displayed higher GIA activity at lower (1%) serum dilutions (p < 0.0001); (2) there was significant relationship between GIA activity, parasite clearance rate (p = 0.05) and slope half-life (p = 0.025); and (3) age was a confounding factor when comparing the GIA activity with parasite clearance kinetics. Conclusion This study demonstrates for the first time there is synergy of complement, pre-existing immunity, and drug treatment in younger patients with symptomatic malaria in a high-transmission area.
Schizophyllum commune induced oxidative stress and immunosuppressive activity in Spodoptera litura
Authors: Kaur Mandeep , Chadha Pooja , Kaur Sanehdeep , Kaur Amarjeet , Kaur Rajvir 
Published: April 2020

Abstract
Background: In the last few decades, considerable attention has been paid to fungal endophytes as biocontrol agents, however little is known about their mode of action. This study aimed to investigate the toxic effects of an endophytic fungus Schizophyllum commune by analyzing activities of antioxidant and detoxifying enzymes as well as morphology of haemocytes using Spodoptera litura as a model. Results: Ethyl acetate extract of S.commune was fed to the larvae of S.litura using the artificial diet having 276.54µg/ml (LC 50 of fungus) concentration for different time durations. Exposed groups revealed, significant (p≤0.05) increase in the activities of various enzymes viz. Catalase, Ascorbate peroxidase, Superoxide dismutase, Glutathione-S-Transferase. Furthermore, haemocytes showed various deformities like breakage in the cell membrane, cytoplasmic leakage and appearance of strumae in the treated larvae. A drastic reduction in the percentage of normal haemocytes was recorded in the treated groups with respect to control. Conclusion: The study provides important information regarding the oxidative stress causing and immunosuppressant potential of S.commune against S.litura and its considerable potential for incorporation in pest management programmes.
Implementing selective-prevention primary care interventions targeting cardio-metabolic diseases in five European countries: the SPIM-EU project
Authors: Lionis Christos D , Anastasaki Marilena , Bertsias Antonios , Angelaki Agapi , Carlsson Axel C , Gudjonsdottir Hrafnhildur , Wändell Per , Sonderlund Anders L , Thilsing Trine , Søndergaard Jens , Seifert Bohumil , Kral Norbert , Wit Niek de , Hollander Monika , Korevaar Joke , Schellevis François G 
Published: April 2020

Abstract
Background

Cardio-metabolic diseases are the most common cause of death worldwide. Implementing selective prevention strategies has proven a substantial challenge, especially in primary care.
Objectives

As part of a collaborative European study, this paper aims to assess the implementation of primary care selective prevention interventions in the Czech Republic, Denmark, Greece, the Netherlands and Sweden. We sought to determine participants’ cardio-metabolic risk profile, as well as their evaluation of the intervention in terms of feasibility and impact in promoting a healthy lifestyle.
Methods

A selective prevention intervention, including patient invitation and cardio-vascular risk assessment using country-adjusted tools, was implemented. Eligible participants were primary care patients, 40–65 years of age, without any diagnosis of cardio-metabolic disease. Main outcomes included intervention acceptance and completion rates. Patient demographics, lifestyle-related cardio-metabolic risk factors, and opinions on intervention feasibility were recorded. Findings are summarized descriptively.
Results

In each country, 200 patients were invited to participate in the study. Acceptance rates varied from 19.5% (n = 39/200) in Sweden to 100% in the Czech Republic (n = 200/200). Risk assessment completion rates ranged from 65.4% (n = 70/107) in Greece to 100% (n = 39/39) in Sweden. Twelve individuals (6.9%) were identified as being at high risk of cardio-vascular disease in the Czech Republic, five (8.6%) in Denmark, eight (11.4%) in Greece, 21 (36.8%) in the Netherlands and none (0%) in Sweden. On a ten-point scale, the median (25%-75% quartile) of participant-reported intervention feasibility ranged from 7.4 (6.9–7.8) in Greece to 9.2 (8.2–9.9) in Sweden. Willingness to change lifestyle exceeded 80% in all countries, with the desire for better health representing the main motivating factor for more than half of the participants.
Conclusions

Although substantial variations in patient cardio-metabolic risk profile and intervention receptiveness were observed, our findings add to existing evidence regarding the implementation of selective prevention programs in European primary care and can be used as part of future cardio-metabolic risk reduction strategies.
Rigorous Measures are Vital for Preventing and Controlling Coronavirus Disease 2019 (COVID-19): A Cross-sectional Study
Authors: Yu Lushi , Wang Yi , He Haihua , Chu Yuxin , Feng Hongyan , Wei Yuehua , Zhou Jin , Song Qibin , Gong Hongyun 
Published: April 2020

Abstract
Background Since December 2019, a novel corona virus disease named COVID-19 outbreak in Wuhan, China and spread worldwide then. Active prevention and control measures have been carried out in China, such as vigorous publicity, active screening and rapid isolation. As the major epidemic area, the passages in and out of Wuhan were temporarily closed since January 23. We aimed to demonstrate the effectiveness of rigorous measures by comparing the characteristics of patients hospitalized before and after implementation of vital measures. Methods Clinical data of patients admitted to hospital with COVID-19 during January 17-23 (Phase I) and February 3-9 (Phase II) were collected and compared. The cut-off date for follow-up was March 13, 2020. Results Of 176 patients with COVID-19, 97 were admitted in Phase I (43 [44.3%] male; mean age: 47.7), and 79 were in Phase II (33 [41.8%] male; mean age: 50.1). The proportions of severe cases were 21.6% and 10.1% respectively. Fewer patients had comorbidities (13 [16.5%] vs. 7 [7.2%]) and more asymptomatic patients were in Phase II (27.8% vs. 13.9%). Patients in Phase II had less fever (53.2% vs. 70.1%), cough (34.2% vs. 52.6%) and myalgia (11.4% vs.28.9%), while more diarrhea (11.4% vs. 2.1%). Lymphopenia and elevated CRP, as well as eosinopenia and elevated SAA were common in two groups, but all of that were significantly better in Phase II. More patients in Phase II preformed normal CT image on admission (10 [12.7%] vs. 7 [7.2%]). And lower CT scores (3 [2-4] vs. 2 [1-3]) were observed in Phase II. Up to cut-off date, average response time on CT image were 11.2 and 8.1 days in Phase I and II respectively. Shorter average hospitalized days were in Phase II (18.9 vs. 23.3 days). Four patients (4.1%) in Phase I and two (2.5%) in Phase II died. Conclusions Various actions (including vigorous publicity, active screening and rapid isolation) prompted more early patients with COVID-19 found, diagnosed and remedied, leading to good prognosis. Call for pretty attention to the epidemics of COVID-19 and timely measures around the world.
“…This facility has all that is Required for Safe Baby Delivery in Case of An Emergency There is a Theater…” Exploring Experiences and Perceptions of Quality of Maternity Care in a Rural Sub-County. A Qualitative Study
Authors: Oluoch-Aridi Jackline Akinyi , Wafula Francis , Kokwaro Gilbert O , Adam Mary B 
Published: April 2020

Abstract
Background Maternal mortality still remains a big health system challenge in Kenya. Free maternity policy resulted in an increase in Facility-based delivery. However, this has not been accompanied with a reduction in maternal mortality. This research aims at establishing women’s experiences and perceptions with regard to the quality of maternal health services received at health facilities during delivery. This contextual knowledge will assist policy makers to better understand patterns of health system utilization critical for forging strategies for reducing inequities and providing high quality maternal care.Methods Women aged between 18 and 49 who had recently delivered and were attending six-week immunization clinics were purposively selected at six different health facilities and focus group discussions were conducted with the women. The data was analyzed using thematic content analysis. Verbatim excerpts from the women were provided to illustrate the themes identified. The WHO vision for quality of care was used to assess the themes on experiences of care described by the womenResults Six themes were identified as facilitators to access maternal health services 1) Perceived quality of delivery services 2) Financial access to delivery services 3) Referrals to public tertiary health facilities 4) Social influence 5) operation times at public primary health facilities 6) Distance to the health facility. A few barriers were identified under the perceived quality of services most prominent been the mistreatment of women by night-shift nurses and the operation time at the primary health facilitiesConclusion The findings suggest that the rural women tend to prefer tertiary maternity health facility and there are a number of factors related to quality of care based on their experiences that predispose their choices. Most prominent was the availability of equipment such as theatres for obstetric complications. Another emerging issue was respectful care during maternity services. Auxiliary costs still present a challenge despite the free maternity services. Future studies need to focus on ensuring in depth contextual understanding of women’s perceptions of the experience of care with regard to patient-centered care. Understanding these aspects will help in forging strategies to reduce inequities that are leading to high maternal mortality