bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of penol on the GABA receptor-coupled Cl/HCO-ATPase from rat brain in / experiments
Authors: Мензиков С.А. 
Published: December 2020

Фенол (гидроксибензол) является токсичным веществом. Одним из клинических признаков проявления эффекта высоких доз фенола на животных является судорожная активность, молекулярные механизмы которой остаются неясными. Цель исследования - изучение молекулярных механизмов судорожной активности при действии токсиканта (фенол) с нервно-паралитической природой действия. Методика. Исследована роль Cl/HCO-АТФазы, которая участвует в ГАМК рецептор-сопряженном АТФ-зависимом Cl-транспорте через нейрональные мембраны мозга животных. Результаты. Исследования in vivo показали, что после внутрибрюшинной инъекции животным фенола (300 мг/кг) наблюдается судорожная реакция, при этом АТФазная активность мозга крыс не выявляется. В экспериментах in vitro установлено, что фенол (500 мкМ) полностью ингибирует функциональную активность Cl/HCO-АТФазы нейрональных мембран мозга крыс. Заключение. Делается вывод о важной роли нейрональной Cl/HCO-АТФазы в патогенезе и проявлении судорожных ответов у животных.
Phenol (hydroxybenzene) is a toxic substance with a neuroparalytic nature of action. One of the clinical signs of the manifestation of the effect high doses of phenol on animals is convulsive activity, the molecular mechanisms of which remain unclear. Aim. In order to clarify these mechanisms, in the present work we investigated the role of Cl/HCO-ATPase, which is involved in GABA receptor-coupled ATP-dependent Cl-transport through the plasma membranes of the neurons of animals brain. Results. In vivo studies have been shown that after intraperitoneal injection of phenol at a dose of 300 mg/kg to the animals, a convulsive reaction is observed, while the Cl/HCO-ATPase of the rat brain is not detected. In in vitro experiments, it was established that phenol (500 мM) completely inhibits the functional activity of the Cl/HCO-ATPase of the neuronal membranes from rat brain. It was assumed the important role of neuronal Cl/HCO-ATPase in the pathogenesis of phenolic neurotoxicity and the manifestation of convulsive responses in animals.
The brain-derived neurotrophic factor (BDNF) system as a therapeutical target for development of drugs restoring innervation
Authors: Стамбольский Д.В. , Плеханова О.С. , Юдина И.Ю. , Калинина Н.И. , Карагяур М.Н. , Дубров В.Э. , Кочиш А.Ю. , Семина Е.В. , Акопян Ж.А. , Голубев И.О. , Антонов А.В. , Сафин Ш.М. , Ткачук В.А. 
Published: December 2020

Мозговой нейротрофический фактор (BDNF) является одним из основных нейротрофических факторов, участвующих в поддержании функционирования и регенерации нервной системы. В последние годы BDNF рассматривают как многообещающую терапевтическую мишень, на основании полученных данных о том, что BDNF улучшает регенерацию нейронов. Цель обзора - суммировать данные об экспрессии BDNF, его сигнализации, эффектах и механизмах стимуляции реиннервации. Анализ исследований последних десятилетий позволяет сделать заключение о целесообразности и перспективности разработок, направленных на создание лекарственных препаратов на основе BDNF для регенерации компонентов нервной системы.Brain-derived neurotrophic factor (BDNF) is a major neurotrophic factor maintaining the nervous system function and regeneration. Based on reports indicating that BDNF enhances neuronal regeneration, in recent years, BDNF has been considered a promising therapeutic target. The aim of this review was to summarize current data on BDNF expression, signaling, and mechanisms for stimulation of reinnervation. Conclusion. Recent studies of the role of BDNF showed that continuation of research and development of BDNF-based drugs stimulating regeneration of nervous system components is advisable and promising.
Pengaruh Kepatuhan Wajib Pajak Terhadap Peningkatan Pendapatan Pajak Kendaraan Bermotor Di Kantor Samsat Kabupaten Enrekang
Authors: Riswanto Riswanto , Hakim Lukman , Haerana Haerana 
Published: December 2020

ABSTRACTThe purpose of this study was to determine taxpayer compliance, increase in tax revenue and the effect of taxpayer compliance on the increase in motor vehicle tax revenue at Samsat Office of Mamuju Regency. This study used quantitative. The number of samples was 99 taxpayers registered at Samsat Office of Mamuju Regenc. Data collection techniques were observation, questionnaires and documentation. The type of research used quantitative research. The results showed that there was a direct effect of taxpayer compliance on the increase in motor vehicle tax revenue at the Samsat Office of Mamuju Regency. Based on the results of the study showed that there was a positive and significant relationship so there was an effect of tax compliance (x) on an increase in motor vehicle tax revenue (y) in the Samsat Office of Mamuju Regency by 54.9% and the remaining 45.1% was influenced by other variables not examined in this research. From the results of this study known that there were still several important indicators that still needed more attention to increase tax revenue in Mamuju Regency.Keywords: Taxpayer compliance, Increased tax revenue
DIREITO À CIDADE E PESSOAS COM DEFICIÊNCIA: O BEM-ESTAR URBANO COMO VETOR PARA A EFETIVAÇÃO DE DIREITOS
Authors: Nery da Silva Rogério Luiz , Mattiello Darléa Carine Palma 
Published: December 2020

A pesquisa insere-se no estudo da efetivação dos direitos sociais para as pessoas com deficiência, com recorte no direito à cidade, sustentabilidade e bem-estar urbano. O objetivo geral do trabalho é verificar os fatores determinantes para averiguar os critérios de efetivação dos direitos sociais às pessoas com deficiência nas cidades a partir da apuração do índice de bem-estar urbano. A pesquisa é bibliográfica e documental, com abordagem qualitativa e predominância do método dedutivo. Em conclusão, o trabalho aponta que parâmetros como mobilidade e infraestrutura são alicerces para a aferição da efetividade de direitos às pessoas com deficiência nas cidades.
Precariedad y abyección en Wilson Paccha
Authors: Córdova Franciné 
Published: December 2020

El presente análisis aborda la práctica artística de Wilson Paccha y su estrategia para manipular las normas del arte desde la marginalidad, insertando lo imposible de ser nombrado al arte contemporáneo del contexto quiteño, pero también me interesa hacer una crítica al proceso de abyección de Paccha, como efecto de los regímenes estéticos en “el reparto de lo sensible”[1] con el modelo de lo tradicional establecido en ciertos espacios académicos, cuyo centro creó un otro que quedó por fuera, sin parte. La irrupción de un arte tocante a lo etnográfico es la contra mirada de las nuevas formas de producir arte. Paccha de formación tradicional ve en este arte la oportunidad para entrar y salir del campo artístico con su obra, pone en entre dicho la visualidad de las formas artísticas tradicionales del arte representacional, instaladas en el imaginario como las únicas formas estéticas del arte.

[1] “Un reparto de lo sensible fija al mismo tiempo algo común repartido y ciertas partes exclusivas” (Ranciere 2014, 19)
El sueño en la penúltima escena en la película No country for old men de los Hermanos Coen y una interpretación del poema Sailing to Byzantium de William Butler Yeats
Authors: Benalcázar Pijal Corina 
Published: December 2020

La presente investigación propone una lectura de la penúltima escena de la película: No country for old men (No es país para viejos) (2007) de los hermanos Joel y Ethan Coen. El filme es una adaptación de la novela homónima de Cormac McCarthy (2005), y ésta, a su vez, es una interpretación del poema Sailing to Byzantium de William Butler Yeats (1928). Si bien el resultado cinematográfico guarda una relación directa con la novela, también lo hace con el poema, pero no de manera evidente. De modo que el presente texto analiza tanto la penúltima escena de la película como el poema, para platear una relación entre ellos.
O colapso no sistema penitenciário do sul da Bahia: o dever do estado e as parcerias público-privadas
Authors: Bogo Ademar , Santos Sérgio , Fagundes Rosélia 
Published: December 2020

Este é o resultado de um estudo realizado junto ao sistema prisional na particularidade da região Sul da Bahia. Buscou investigar como vem sendo implantadas as Parcerias Público-Privadas no sistema prisional em colapso, observando em que medida o Estado tem cumprido com o dever expresso no artigo 1º, inciso III, da Constituição da República Federativa do Brasil de 1988 – postulado central do ordenamento jurídico pátrio, um fundamento axiológico sob o qual está constituído o Estado Democrático de Direito: dignidade da pessoa humana, aos que encontram-se subsumidos nas barbáries do sistema prisional brasileiro especificamente. Trata-se de um estudo bibliográfico com consulta a documentos disponíveis e escritos de autores sobre a temática, bem como o suporte de dados e opiniões extraídas de entrevistas realizadas com autoridades vinculadas ao sistema prisional no Sul do Estado da Bahia. Os resultados evidenciados apontam que as Parcerias Público-Privadas no Sul da Bahia vêm sendo implantadas parcialmente devido à opção pelo sistema de cogestão que é apenas um estágio intermediário entre o papel de encarcerar e a responsabilidade de reeducar o apenado. Tendo em vista as condições de superlotação dos presídios, o pouco envolvimento dos presos nos programas e o alto índice de reincidência, o sistema carcerário no Sul da Bahia, em estado de colapso, precisa de urgente reformulação.
USE OF ICT BASED LIBRARY RESOURCE AND SERVICES IN CONSTITUENT FIRST GRADE COLLEGES AFFILIATED TO UNIVERSITY OF MYSORE: STUDY
Authors: Chikkamanju  , Ambika  , Ali Hydar 
Published: December 2020

The study investigated the ICT based library and Information services in Constituent First Grade Colleges affiliated to University of Mysore .The present study demonstrates and elaborates the primary way to learn about ICTs, the purpose of using ICT enabled library services, to assess to what extent users are utilized ICT based library services and facilities, various aspects of Internet usage, favourite search engines, NLIST resources and services Suggestions have been given to make the service more beneficial in the library users.
The aims were to examine impacts of ICT on motivation and related issues such as learning outcomes, behaviour, and attendance and to quantify any impacts where possible. The study also set out to consider the ways in which ICT can best be used by under graduate students to enhance motivational impacts for pupils, especially for those disaffected with traditional forms of learning.
The present study aims to examine the ICT based library and Information services in Constituent First Grade Colleges affiliated to University of Mysore. The questionnaire method was adopted for the present study to collect the necessary data, keeping in view the objectives of the study. Total 236 questionnaires were distributed and 163 filled in questionnaires were collected back. The rate of response of 69.06 %. The collected data has been analysed using appropriate statistical techniques with SPSS such as chi-square test, mean and standard deviation for the analysis.
The majority mean value of 3.28 SD being 1.66 I read e-Books of respondents110(67.48%) of students opine as ‘Excellent’, with a mean value of 1.59 and SD being 1.00. for Preferred search engine 20(12.26%) respondents use ‘Annual Reviews’ Use of N-List resources and Services
From the analysis, it showed that our colleges should always embark on strategies towards adding more value to their ICT based library services. ICT based library services awareness program should be rendered to the graduate students at the very point of enrolment into the graduate studies for this will help the students to - wards understanding the need of utilizing the library properly and also appreciate technology more in their lives.
Penerapan Strategi Pembelajaran (Think Talk Write) TTW Untuk Meningkatkan Hasil Belajar Dan Kemampuan Berfikir Kritis Matematika Pada Materi Pokok Bahasan Persamaan lingkaran Matematika Di Kelas XI SMK Amanatul Ummah Pegantenan Pamekasan
Authors: Rohmah Ulfatur , Maulana Aslih 
Published: December 2020

Penelitian ini bertujuan untuk mengetahui: apakah penerapan (Think Talk Write) TTW pada materi pokok bahasan persamaan lingkaran dapat hasil belajar dan kemampuan berfikir kritis matematika peserta didik kelas XI SMK Amanatul Ummah Pegantenan Pamekasan. Jenis penelitian ini adalah penelitian tindakan kelas(PTK). Subjek penelitian ini adalah peserta didik kelas XI SMK amanatul umamah pegantenan pamekasan yang jumlah peserta didiknya 23 orang, terdiri dari 11 perempuan dan 12 laki-laki.. Metode pengumpulan data yang digunakan adalah observasi dan tes. Penelitian tindakan kelas ini dirancang dalam 2 (dua) siklus, setiap siklus ada 4 (empat) tahap yaitu perencanaan (planning), tindakan (action), Pengamatan(observation), dan refleksi (reflection
Hasil belajar pada kondisi awal rata-rata sebelum dilakukan penelitian yaitu 60 dengan presentase ketuntasan 39%. Setelah dilakukan penelitian siklus I menggunakan strategi pembelajaran Think-Talk-Write mengalami peningkatan dengan nilai rata-rata 77,44 dengan peresentase ketuntasan mencapai 83%.untuk kemampuan berpikir kritis pada kondisi awal rata-rata sebelum dilakukan penelitian yaitu 50,5 (tidak kritis) dengan presentase 44,7% (tidak kritis). Setelah dilakukan penelitian siklus I menggunakan strategi pembelajaran Think-Talk-Write mengalami peningkatan dengan nilai rata-rata 72,8 (kritis) dengan peresentase mencapai 79,3% (kritis).
Dari data tersebut, dapat disimpulkan bahwa model pembelajaran (Think Talk Write) TTW dengan melalui delapan langkah- langkahnya dapat meningkatkan hasil belajar dan berpikir kritis peserta didik pada pokok pada materi pokok persamaan lingkaran kelas XI SMK Amanatul Ummah Pegantenan Pamekasan. Keberhasilan penggunaan metode tersebut diharapkan bisa digunakan sebagai alternatif pendekatan pembelajaran yang inovatif. Selanjutnya para guru dapat lebih berkreasi dalam menggunakan model pembelajaran yang sesuai dengan tujuan pembelajaran.
KORUMA AMAÇLI TOPRAK EDİNİMLERİ TOPRAK GASPININ BİR PARÇASI VE TAMAMLAYICISI OLARAK DEĞERLENDİRİLEBİLİR Mİ?
Authors: AK KURAN Sabriye 
Published: December 2020

ÖZ
İnsanlık tarihi boyunca gıda insanların temel ihtiyaçlarından birisi olmuş ve küresel nüfustaki artışa bağlı olarak gıda ürünlerine olan talep de sürekli artmıştır. Sınırlı bir kaynağa sahip olan gezegenimizde bu talebin karşılanabilmesi, toprağın metalaştırılması yoluyla gerçekleştirilmiştir. Literatürde bu olguya toprak gaspı denilmektedir.
Buradan hareketle çalışmada, ilk olarak toprak gaspı kavramı, kapsamı, toprak gaspında arazi kullanım biçimleri ve gaspın etkileri analiz edilmektedir. İkinci olarak, koruma amaçlı toprak ediniminin (yeşil gasp) toprak gaspı kapsamında değerlendirilip değerlendirilemeyeceği tartışılmaktadır. Arjantin, Meksika, Kolombiya, Mozambik ve Uganda’daki yeşil gasp örnekleri koruma amaçlı toprak ediniminin toprak gaspının tamamlayıcısı ve destekleyicisi olduğunu göstermektedir. Ayrıca söz konusu saha araştırmaları toprağı metalaştırma yoluyla korumanın mümkün olamayacağına ilişkin işaretlerle doludur.
Anahtar Kelimeler: Toprak Gaspı, Yeşil Gasp, Metalaştırma, Koruma, Gıda Egemenliği.
Trama de vinculaciones personales y profesionales desde la voz del profesor
Authors: García Martel María Luisa , Mieres Ilda Avelina 
Published: December 2020

<p>Este artículo se configura en torno a una indagación respecto del currículum vitae de una docente y al análisis del mismo desde la perspectiva relacionada con la noción de currículum como espacio de formación disciplinaria. Cobró sentido en este trabajo la idea de significatividad; entendida ésta como principio subyacente de selección que explica las elecciones; actitudes; decisiones y adhesiones que el individuo expresa y realiza; en este caso particular en relación con la vida profesional.</p><p>El enfoque cualitativo fue el pilar metodológico de este trabajo ya que se buscó comprender una situación particular; contextualizada en un tiempo histórico determinado. Por ello se revalorizó la perspectiva de los actores involucrados.</p><p>Las conclusiones giran; en principio; en torno a la posibilidad de describir el trayecto profesional de un docente; mostrando diferentes actividades de una persona en un ordenamiento espacial y temporal determinado. Se pueden identificar períodos o etapas en diferentes niveles y funciones y se advierten; además; períodos de aceleramiento y condensación de actividades que hace pensar en una intensificación laboral. Asimismo; se identifican segmentos temporales en los que el camino se presenta pautado; lento; sereno; por tramas particulares de la vida personal. Vale la pena destacar la importancia ejercida por las presiones políticas y sociales en tiempos de ocupar cargos jerárquicos; siendo detonantes de renuncias en el desempeño profesional. La cuestión de la significatividad puso en el centro de la escena el entramado singular de la esfera personal con la esfera profesional. </p>
Abordajes del Curriculum desde la inclusión de la dimensión ambiental en ofertas académicas en la Universidad Nacional del Nordeste
Authors: Sudar Klappenbach Luciana , Peralta Erica Silvana 
Published: December 2020

<p>Este trabajo denominado “Abordajes del Curriculum desde la inclusión de la dimensión ambiental en ofertas académicas en la Universidad Nacional del Nordeste”; es parte de los primeros resultados de un Proyecto de Investigación acreditado por la Secretaría General de Ciencia y Técnica de la Universidad Nacional del Nordeste.</p><p>El objetivo fue identificar y analizar la presencia o ausencia de la Dimensión Ambiental (DA) en las ofertas académicas de la UNNE a partir del análisis de los Planes de Estudio. Se adoptó; en esta instancia una metodología de naturaleza cualitativa; de carácter descriptivo apoyada en un trabajo de Eschenhagen Durán (2009). En esta ocasión se hizo una revisión de todas las carreras; a fin de poder identificar aquellas que contemplaban en los Planes de Estudio la inclusión de la DA. Para lo cual se emplearon técnicas descriptivas basadas en la revisión y análisis de documentos oficiales; tales como los planes de estudio; enmarcadas en la revisión de antecedentes y bibliografía especializada; y posteriormente la sistematización de información y lectura cuantitativa de los datos.</p><p>Los avances hasta aquí alcanzados permitieron identificar la existencia en la UNNE de un total de 51 carreras de grado; con 14 de pregrados (tecnicaturas); distribuidas en 12 Unidades Académicas; de las cuales 20 carreras se vinculan con la DA; 17 corresponden a nivel de grado y 3 en pregrado. Realizar el análisis de las siete áreas posibilitó también identificar el contexto en que la DA toma protagonismo al momento de definir la formación universitaria.</p>
A Fast and Reliable Screening Method of Organic Materials for Crop Cultivation
Authors: Park Seunghye , Joo Se-hwan , Kim A-Leum , Shin Ji-Hwan 
Published: December 2020

Strategic utilization of organic material for agriculture is important for improve efficiency in organic agriculture. Waste from food processing is a good candidate for compost material, and the first critical step is to choose proper raw material. In this study, we tried to establish a reliable screening method by comparing growth of different plant parts in different crops in combination with serial dilution of raw material extracts. The raw materials compared here are tangerine pomace, herbal medicinal plant waste, bread, spent coffee ground (SCG). We also compared effect of organic fertilizer made of SCG, natural pesticides made of pyrethrum extract and neem oil. The results obtained from different kind of crops and plant parts give insight into growth enhancing or inhibitory effect of tested material which will be useful screening raw material to make organic fertilizer and crop protective materials.
Int. J. Appl. Sci. Biotechnol. Vol 8(4): 417-421
Evaluation and Release of High Yielding and High Oil Containing Mustard for Terai and Inner Terai of Nepal
Authors: Yadav Bisheswar Prasad , Rasaily Santosh , Wagle Pramod , Malla Razan , Kandel Manoj , B.K. Nabina , Aryal Sheetal 
Published: December 2020

In Recent years, cultivation of Mustard (Brassica juncea) is growing popularity but there is lack of suitable high yielding and oil contenting variety in Nepal. With Objective of identifying and releasing of high yielding variety, evaluation of exotic genotypes were done in the research field and farmers field. Coordinated Varietal Trial (CVT) was conducted for three years in three different location (Nawalpur, parwanipur and Khajura) in RCBD design. 4 Elite genotypes were selected and further evaluate under Coordinated Farmer Field Trial (CFFT) for 5 years where each farmer was considered as Replication. Nutrients Analysis was done to find out the moisture, oil and protein content of selected elite genotypes. In combined ANNOVA of CVT, ICJ 9704 was found to be high yielding genotypes. Similarly, In CFFT, genotypes was significantly for yield where ICJ 9704 produced highest yield (906.75 kg/ha) where as Divya, Pusa Jagarnath and Krishna produced yield of 798.12 kg/ha, 790 kg/ha and 767.392 kg/ha. ICJ 9704 has high oil content 37.3 % with 36.3 % protein content. In 2017, ICJ 9704 was release as Morang rayo and was recommended to grow in the terai and inner terai. Hope this variety will be popular among mustard growing farmer and will help to meet the national demand of the Nation.
Int. J. Appl. Sci. Biotechnol. Vol 8(4): 454-456
Gender Differences in the Clinical Characteristics of Patients with Acute Coronary Syndrome in the Eastern Region of Nepal
Authors: Dhungana Sahadeb Prasad , Adhikari Roshna , Khatiwada Sameen 
Published: December 2020

Background: Studies from other regions show gender-based differences in the clinical characteristics of patients with the acute coronary syndrome (ACS) with conflicting results. There is a lack of definite data from our population.
Materials and Methods: This is a hospital-based cross-sectional study in patients with ACS admitted to the tertiary care center from January 2019 to June 2020. Risk factors, co-morbidities, clinical symptoms, duration of symptoms onset, modalities of treatment offered, complications, and in-hospital outcome were noted in the pre-structured questionnaire by convenient sampling. Data were analyzed by using Microsoft excel 2007 and SPSS 20.
Results: Among 384 participants, 65.9% were male and 34.1% were female. The mean age of males was 60.6 ± 12.1 and females 62.3 ± 11.1 years (P=0.21). Females had a higher prevalence of dyslipidemia (p<0.001). The prevalence of hypertension, diabetes, and smoking was similar. The mean hemoglobin level was higher in males (11.8 ± 2.2 gm/dl vs. 11.1 ± 4.57 gm/dl, P = 0.01). The majority presented with chest pain (94.9%) in males and 87.8% in females, P=0.44), and sweating (76.7% in males and 80.2% in females, P=0.43). Non-anginal symptoms were almost similar in both the genders except nausea which was more common in males (P=0.03). The timing of presentation, treatment with reperfusion therapy, and arterial territory involved were not significantly different. Prevalence of mechanical and arrhythmic complications as well as mortality was similar.
Conclusion: Our study did not show significant gender-based differences in clinical profile, treatment modalities, in-hospital complications, and mortality.