bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Hemorrhagic Edema of Infancy: A Diagnostic Challenge for the General Pediatrician
Authors: Leung Alexander K.C. , Leong Kin F. , Lam Joseph M. 
Published: July 2020

Background::
Acute hemorrhagic edema of infancy (AHEI), a benign and self-limited
disease, can be easily mistaken to be a number of diseases with similar dermatological manifestations
but with potentially adverse outcomes.

Objective:
This review aimed to familiarize pediatricians with the natural history, clinical manifestations,
diagnosis, and management of AHEI.

Methods:
A PubMed search was conducted in February 2020 in Clinical Queries using the key
terms “acute hemorrhagic edema of infancy” OR “Finkelstein disease” OR “Seidlmayer disease”.
The search strategy included meta-analyses, randomized controlled trials, clinical trials, observational
studies, and reviews published within the past 10 years. Only papers published in the English
literature were included in this review. The information retrieved from the above search was used
in the compilation of the present article.

Results:
AHEI, a rare cutaneous leukocytoclastic small-vessel vasculitis, typically presents with
palpable purpura, peripheral acral edema, and frequently with fever, most often in children between
4 and 24 months of age. A significant number of children experience prodromal symptoms of an
upper respiratory infection. Fever is typically low grade and is present in approximately 50% of
cases. The cutaneous lesions are characterized by rapid onset of small erythematous macules or
papules that progress to well demarcated, annular, rosette, medallion-like, or targetoid purpuric
plaques or ecchymosis in 24 to 48 hours. The skin lesions are typically palpable, nonpruritic, and
symmetrically distributed. Sites of predilection include the face, auricles, and extremities. Edema is
typically nonpitting and asymmetrical and occurs primarily on the dorsum of the hands and feet,
the face, and the auricles. In spite of the acuteness and extent of the cutaneous findings, the child
looks well and nontoxic. Systemic and/or visceral involvement are rare. The differential diagnosis
is broad and includes, among others, Henoch-Schönlein purpura. It is crucial to distinguish AHEI
from the other diseases since the management of these diseases is quite different. The clinical features
of mimickers of AHEI are reviewed and clues to differentiate AHEI from these mimickers are
highlighted..AHEI is a benign, self-limited disease with complete spontaneous recovery in one to
three weeks in the majority of cases.

Conclusion:
Recognizing this rare disease is important for the pediatrician to rapidly differentiate
AHEI from other potentially serious diseases that require prompt therapy and monitoring. With
rapid recognition of AHEI, unnecessary investigations and inappropriate interventions can be prevented
and parental anxiety can be avoided.
In silico Study to Evaluate the Antiviral Activity of Novel Structures against 3C-like Protease of Novel Coronavirus (COVID-19) and SARS-CoV
Authors: Chunduru Kiran , Sankhe Runali , Begum Farmiza , Sodum Nalini , Kumar Nitesh , Kishore Anoop , Shenoy Rekha R. , Rao Chamallamudi M. , Saravu Kavitha 
Published: July 2020

Background:
Globally, over 4.3 million laboratory confirmed cases of COVID-19 have
been reported from over 105 countries. No FDA approved antiviral is available for the treatment of
this infection. Zhavoronkov et al., with their generative chemistry pipeline, have generated structures
that can be potential novel drug-like inhibitors for COVID-19, provided they are validated. 3C–like
protease (3CLP) is a homodimeric cysteine protease that is present in coronaviruses. Interestingly,
3CLP is 96.1% structurally similar between SARS-CoV and SARS-CoV-2.

Objective:
To evaluate interaction of generated structures with 3CLP of SARS-CoV (RCSB PDB ID:
4MDS).

Methods:
Crystal structure of human SARS-CoV with a non-covalent inhibitor with resolution: 1.598
Å was obtained and molecular docking was performed to evaluate the interaction with generated
structures. The MM-GBSA and IFD-SP were performed to narrow down to the structures with better
binding energy and IFD score. The ADME analysis was performed on top 5 hits and further MD
simulation was employed for top 2 hits.

Results:
In XP docking, IFD-SP and molecular dynamic simulation studies, the top 2 hits 32 and 61
showed interaction with key amino acid residue GLU166. Structure 61, also showed interaction with
HIS164. These interactions of generated structure 32 and 61, with GLU166 and HIS164, indicate the
binding of the selected drug within the close proximity of 3CLP. In the MD simulation, the protein–
ligand complex of 4MDS and structure 61 was found to be more stable for 10ns.

Conclusion:
These identified structures can be further assessed for their antiviral activity to combat
SARS-CoV and COVID-19.
COVID 19, All a Radiologist Needs to Know: A Narrative Review
Authors: Shobeirian Farzaneh 
Published: July 2020

Background:
Coronaviruses are non-segmented enveloped positive-sense single-strand
RNA viruses, and COVID-19 is the seventh known coronavirus, infecting humans.

Objective:
As the COVID-19 continued to spread the world wildly, every radiologist or clinician
needs to be familiar with its imaging findings.

Methods:
In this study, we reviewed available studies to provide a comprehensive statement on
COVID-19 imaging findings.

Results:
Ground-glass opacities, linear opacities, interlobular septal thickening, consolidation, and
Crazy-paving patterns are the most frequent findings in computed tomography (CT) of lungs in
patients with COVID-19 pneumonia, which are mostly bilateral, multifocal, and peripheral. Staff
needs to follow some rules to reduce infection transmission.

Conclusion:
COVID-19 pneumonia is a new global concern that has many unknown features. In this
article, the radiologic characteristics of COVID-19 pneumonia are discussed. We also discussed
appropriate protective measures that the radiology team should be aware of.
Levofloxacin Versus Ceftriaxone for the Treatment of Acute Pyelonephritis in Iranian Adults
Authors: Tehrani Shabnam , Elyasi Fereshteh , Abolghasemi Sara 
Published: July 2020

Introduction:
Acute pyelonephritis is among the most common bacterial infections. Options
for initial treatment of pyelonephritis include an extended-spectrum cephalosporin or a fluoroquinolone.
This study aimed to compare the clinical outcomes of patients receiving ceftriaxone to
those who received levofloxacin for the treatment of acute pyelonephritis.

Methods:
In this randomized, open-label trial, hospitalized adults with acute pyelonephritis were
treated with ceftriaxone (1g IV every 12 hours) or levofloxacin (750 mg IV daily) for at least 7
days. Clinical and microbiological characteristics were compared among patients treated with ceftriaxone
and levofloxacin.

Results:
A total of 59 patients were randomized, 30 to the ceftriaxone group and 29 to the levofloxacin
group. The clinical response was that 68.0% of patients in the ceftriaxone group and
56.0% of patients in the levofloxacin group were cured. The microbiological response, i.e. pathogen
eradication rates was 68.7% in the ceftriaxone group and 21.4% in the levofloxacin group. (P
value=0.00028) Escherichia coli was the most common pathogen (n = 31), followed by Klebsiella
pneumoniae (n = 21). High resistance rates were detected for cotrimoxazole (55%), ciprofloxacin
(48%), and ceftriaxone (34.4%) in isolated E.coli. Likewise, all K. pneumoniae isolates were resistant
to ciprofloxacin.

Conclusions:
This study indicates that ceftriaxone was more effective than levofloxacin in the treatment
of acute pyelonephritis, on the basis of microbiological response, but there were no statistically
significant differences between the treatment groups in the rates of clinical cure. The resistance
of uropathogens to the most used antibiotics was relatively high. Choosing the treatment regimen
based on susceptibility testing results and shortening the duration of the therapy are now recommended
to be the most important approaches to decrease the spread of antibiotic resistance worldwide.
One Pot Conversion of Carboxylic Acid to Ketone Using Trimethylsilyl Chloride
Authors: Mekonnen Habtamu G. , Jana Samaresh 
Published: July 2020

Background:
Ketone is abundant in many natural products and in pharmaceuticals. It is believed to be one of
the important functional groups in organic chemistry. Till date,several research approaches have been made to access ketone from a readily available starting materials. One such notable transformation consists of the conversion of carboxylic
acid to the corresponding ketone in a one pot manner.

Objective:
We aimed to develop a simple one pot reaction for the conversion of carboxylic acid to ketone. This reaction
could be useful to convert all types of carboxylic acid to ketone in a facile manner.

Methods:
In this procedure, a carboxylic acid has been converted to the corresponding trimethylsilyl ester using trimethylsilyl chloride in the presence of a base. A suitable organometallic reagent can interact with the ester formed at 20°C
to produce the corresponding ketone.

Results:
Under the optimized reaction conditions, various aromatic, aliphatic and heteroaromatic carboxylic acids have
been converted to the corresponding ketones using organolithium reagents, in a one pot manner. Moderate to good yields
of the desired ketones were observed in most of the transformations.

Conclusion:
Conversion of carboxylic acid to ketone has been reported in a one pot fashion, where carboxylic acid has been
transformed to its silyl ester. Organolithium reagents were used as nucleophile for our reaction purpose, whereas the organomagnesium reagents were not useful for this transformation. Aliphatic, aromatic and heteroaromatic carboxylic acids have
been converted to the ketones following a simple process.
Design of Automatic Recharging System of Robot Based on RFID Radio Frequency Technology
Authors: Xiao Zheng 
Published: July 2020

Background:
In order to study the interference of wired transmission mode on robot motion,
a mobile robot attitude calculation and debugging system based on radio frequency (RF) technology
are proposed.

Methods:
Microcontroller STM32 has been used as the control core for the attitude information of
the robot by using MEMS gyroscope and accelerometer. The optimal attitude Angle of the robot is
calculated through nRF24L01, which is the core of the wireless communication module, attitude
acquisition module and wireless data communication upper computer application platform.

Results:
The results show that the positioning accuracy is better than ± 5mm.

Conclusion:
Radio frequency, automatic recharging, infrared ray, positioning accuracy, radio frequency identification, system
structure.
A Novel Dynamic Weight Allocation Method for Assessing the Health Status of Remote Terminal Unit in Distribution Automation System Based on AHM and GRA
Authors: Bian Xinhao , Tang Jinrui , Chen Guoyan , Mo Wenxiong , Wang Hongbin 
Published: July 2020

Background:
The Remote Terminal Units (RTUs) in the Distribution Automation System
(DAS) are widely used in the field in recent years. It is lack of sample data in different operation
status that makes the RTU maintenance improper. The weight allocation for the monitoring indicators
in the health status evaluation needs to be identified efficiently and properly.

Methods:
A systematic health status assessment indicator system is constructed firstly. Then, a hybrid
indicator weight allocation algorithm based on the Attribute Hierarchy Model (AHM) and grey
relational degree (GRA) is proposed to identify the elementary item in the weight allocation under
small sample condition. The final indicator weight would be dynamically adjusted according to the
equilibrium coefficient, which is determined by the indicator condition parameter.

Results:
The simulation results show that the weight allocation can be effectively and reasonably
adjusted according to the indicator value even under small sample condition.

Conclusion:
The expert experience and objective data laws are combined and used in our proposed
dynamic weight allocation method. It can be used to assess the health status of RTU in the electrical
power distribution network.
A Fast and Reliable Balanced Approach for Detecting and Tracking Road Vehicles
Authors: Farag Wael 
Published: July 2020

Introduction:
An advanced, reliable and fast vehicle detection-and-tracking technique
is proposed, implemented and tested. In this paper, an advanced-and-reliable vehicle detectionand-
tracking technique is proposed and implemented. The Real-Time Vehicle Detection-and-
Tracking (RT_VDT) technique is well suited for Advanced Driving Assistance Systems (ADAS)
applications or Self-Driving Cars (SDC).

Methods:
The Real-Time Vehicle Detection-and-Tracking (RT_VDT) is proposed, and it is
mainly a pipeline of reliable computer-vision and machine-learning algorithms that augment
each other and take in raw RGB images to produce the required boundary boxes of the vehicles
that appear in the front driving space of the car. The main emphasis is the careful fusion of the
employed algorithms, where some of them work in parallel to strengthen each other in order to
produce a precise and sophisticated real-time output.

Results:
The RT_VDT is tested and its performance is evaluated using actual road images and
videos captured by the front-mounted camera of the car as well as on the KITTI benchmark. The
evaluation of the RT_VDT shows that it reliably detects and tracks vehicle boundaries under
various conditions.

Discussion:
Robust real-time vehicle detection and tracking is required for Advanced Driving
Assistance Systems (ADAS) applications or Self-Driving Cars (SDC).
REKONTRUKSI ECORELIGIUS ORANG MELAYU Solusi Penyelamatan Lingkungan
Authors: Thamrin, M.Si Husni 
Published: July 2020

Anthropocentric paradigm has distanced humans from nature, as well as causing the humans themselves become exploitative in attitude and do not really care about the nature. In relation, ecological crisis also can be seen as caused by mechanistic-reductionistic-dualistic of Cartesian science. The perspective of anthropocentric is corrected by biocentrism and ecocentrism ethics, particularly Deep Ecology, to re-look at the nature as an ethical community. The concept of ecoculture is already practiced from the beginning by indigenous or traditional societies in elsewhere. The perspective of the human being as an integral part of the nature, and the behaviour of full of resposibility, full of respect and care about the sustainability of all life in the universe have become perspectives and behaviours of various traditional people. The majority of local wisdom in the maintenance of the environment is still surviving in the midst of shifting currents waves by a pressure of anthropocentric perspective. There is also in a crisis because a pressure of the influences of a modernization. While others, drifting and eroding in the modernization and the anthropocentric perspective.In that context, ecoculture, particularly Deep Ecology, support for leaving the anthropocentric perspective, and when a holistic life perspective asks for leaving the anthropocentric perspective, the humans are invited to go back to thelocal wisdom, the old wisdom of the indigenous people. in other words, environmental ethics is to urge and invite the people to go back to the ethics of the indigenous people that are still relevant with the times. The essence of this perspective is back to the nature, back to his true identity as an ecological human in the ecoreligion perspective.
STRATEGI PEMBELAJARAN AKIDAH AKHLAK MELALUI PENDEKATAN SUFISTIK UNTUK MADRASAH TSANAWIYAH PROPINSI RIAU
Authors: Thamrin, M.Si Husni , Yatimin Yatimin 
Published: July 2020

Penelitian tentang Strategi pembelajaran Akidah Akhlak melalui pendekatan sufistik untuk Madrasah Tsanawiyah di Provinsi Riau, merupakan suatu tindakan melatih pikiran siswa sedemikian rupa sehingga dalam sikap hidup dan tindakan dipengaruhi oleh nilai spritual. Mengantar manusia pada prilaku dan perbuatan yang berpedoman pada syari’at Allah.Pembelajaran Akidah Akhlak bukan sekedar “transfer of knowledge” ataupun “transfer of training”. Tetapi lebih merupakan suatu sistem yang di tata di atas pondasi keimanan dan kesalehan. Siklus perkembangan perubahan pembelajaran Akidah Akhlak telah mengikut alur perubahan. Kalau tidak mengikuti alur perubahan, maka pembelajaran Akidah Akhlak akan ketinggalan dari perubahan zaman. Untuk itu pada era tersebut konsep, materi dan kurikulum dihadapkan pada tantangan kehidupan manusia modern, yang serba simpel dan praktis sesuai perkembangan teknologi.Penelitian tentang strategi pembelajaran Akidah Akhlak melalui pendekatan sufistik untuk Madrasah Tsanawiyah merupakan penelitian perpaduan antara penelitian kepustakaan (Library Research), dan penelitian lapangan (Field Research), metode analisis yang digunakan ialah metode content analisis yaitu berangkat dari aksioma bahwa studi tentang proses dan isi komunitas ini merupakan dasar bagi ilmu sosial. Subjek penelitian terdiri Guru Akidah Akhlak dan siswa kelas VII Madrasah Tsanawiyah yang dijadikan sampel di Provinsi Riau. Informan penelitian terdiri dari Kepala madrasah, anggota MGMP Akidah Akhlak dan komponen yang terkait. Tehnik pengumpulan data dengan wawancara, observasi dan dokumentasi. Keabsahan data dengan tehnik trianggulasi metode dan sumber. Tehnik analisis data menggunakan metode content analisis yang terdiri dari; pengumpulan data, reduksi data, penyajian data, dan verifikasi.Hasil penelitian menujukkan: Pembelajaran Akidah Akhlak melalui pendekatan sufistik untuk madrasah tsanawiyah di Provinsi Riau telah menanamkan tiga aspek civic knowledge, civic disposition, civic skill sesuai dengan realitas. Pada akhir pembelajaran tumbuh kesadaran to regcognation and the other dalam kehidupan peserta didik yang beragam sehingga diharapkan menjadi smart and good citizenship dalam konteks sebenarnya.
Peningkatan Pengetahuan dan Keterampilan Pangkas Rambut di Kenagarian Sariak Laweh Kecamatan Akabiluru Kabupaten 50 Kota
Authors: Hayatunnufus Hayatunnufus , Yanita Merita , Dewi Siska Miga 
Published: July 2020

Kegiatan pengabdian ini dilatarbelakangi oleh permintaan dari ibu-ibu PKK Kenagarian Sariak Laweh, Kecamatan Akabiluru, Kabupaten 50 Kota untuk memberikan pelatihan tentang pangkas rambut dalam rangka meningkatkan keterampilan ibu-ibu anggota PKK. Adapun tujuannya (1) memiliki wawasan kemampuan dan keterampilan tentang pemangkasan rambut, (2) meningkatkan mutu proses dan hasil pemangkasan rambut, (3) menumbuhkembangkan keterampilan bidang pangkas rambut sehingga bermanfaat untuk diri sendiri dan orang lain, (4) memberi peluang untuk membuka usaha dan meningkatkan usahanya di bidang pangkas rambut sehingga menambahkan in come bagi keluarga. Target luaran kegiatan ini jurnal berISSN dan video kegiatan. Target yang akan dicapai yaitu meningkatkan keterampilan pangkas rambut dan meningkatkan penghasilan keluarga. Kegiatan ini dilaksanakan di PKK Kenagarian Sariak Laweh, Kecamatan Akabiluru, Kabupaten 50 Kota yang pesertanya terdiri dari 15 orang. Kegiatan ini dilakukan dengan metode ceramah untuk menyampaikan konsep dasar pemangkasan rambut, demonstrasi bagaimana cara melakukan pangkas rambut, tanya jawab, pelatihan pemangkasan rambut dan diberi bimbingan serta metode resitasi pada saat pelatihan. Hasil yang dicapai pada kegiatan ini peserta memperoleh informasi, penyuluhan, serta keterampilan pangkas rambut, sehingga diharapkan peserta pelatihan membuka usaha salon kecantikan khususnya di bidang pangkas rambut. Hasil penelitian terhadap penilaian program, sangat setuju 56,7%, setuju 43,3%, dan kepuasan 73,3% sangat setuju, 26,7% setuju.
Pelatihan Perancangan Kuis dan Video Pembelajaran Interaktif, Sebagai Upaya Peningkatan Kompetensi Pedagogik Guru SLTPN 7 Kota Payakumbuh
Authors: Rahmi Elvi , Cerya Efni 
Published: July 2020

Pemanfaatan teknologi digital dalam pembelajaran di SLTPN 7 Kota Payakumbuh masih belum maksimal, baik sebagai media pembelajaran maupun untuk evaluasi. Metode yang dilakukan dalam pelatihan ini dimulai dengan orientasi materi, setelah dicapai kesepakatan maka pada saat pelatihan diberikan pemaparan mengenai konsep media, evaluasi dan prosedur bagaimana memanfaatkan aplikasi media pembelajaran interaktif (lectora inspire) dan aplikasi kuis (quiz maker). Setelah tahap pemaparan dilanjutkan dengan diskusi dan tanya jawab mengenai tata cara penggunaan aplikasi lectora inspire dan quiz maker. tahap berikutnya adalah latihan terbimbing, latihan mandiri dan ditutup dengan evaluasi.bHasil yang diperoleh dari pelatihan ini adalah guru-guru di SLTPN 7 Kota Payakumbuh bisa mendapatkan pengetahuan, keterampilan, dan pengalaman dalam menggunakan aplikasi lectora inspire dan quiz maker yang berguna untuk meningkatkan kualitas pembelajaran
Pelatihan merancang Jumping Task melalui penerapan Lesson Study for Learning Community (LSLC) bagi guru-guru Bahasa Inggris di MTSN 1 & 6 Padang
Authors: Rozimela Yenni , Anwar Desvalini 
Published: July 2020

Kegiatan pelatihan merancang Jumping Task melalui penerapan Lesson Study for Learning Community (LSLC) bagi guru-guru Bahasa Inggris di MTSN 1 & 6 Padang bertujuan untuk meningkatkan pemahaman dan keterampilan guru dalam mengintegrasikan aktivitas-aktivitas belajar yang dapat mengasah keterampilan berpikir tingkat tinggi dan kritis siswa atau yang dikenal dengan istilah HOTS (High Order Thinking Skill). Jumping Task adalah sejenis tugas yang yang bersifat menantang yang dirancang guru agar siswa-siswanya dapat mengerahkan segenap usaha maksimalnya untuk menyelesaikannya. Tugas-tugas atau latihan-latihan berbasis Jumping Task mendorong siswa untuk tidak hanya berpikir kritis dan kreatif tetapi juga mengembangkan sikap dan nilai-nilai kerja sama atau kolaborasi. Lewat pemberian tugas Jumping Task yang dirancang guru diharapkan siswa menjadi terbiasa berkolaborasi dengan teman sejawatnya, saling berinteraksi dan mengembangkan sikap saling menghargai satu sama lainnya. Kegiatan pelatihan yang berlangsung selama lima kali pertemuan ini melibatkan dua orang dosen sebagai narasumber dan 15 orang guru Bahasa Inggris dari MTSN 1 & MTSN 6 Padang. Pelatihan diisi dengan kegiatan memberikan Pre-Test, pemaparan materi, tanya jawab, merancang latihan-latihan Jumping Task, presentasi, memberikan Post-Test dan melakukan refleksi.
Language in Multicultural Society
Authors: Samajdar Dr. Neerja 
Published: July 2020

Learning a language, is not only learning sounds, alphabets and grammar, but it also means learning the customs and cultural norms. We all grow up in social circles, we informally learn how to use language expressions, gestures, tones. We get to learn the acceptable behaviors or language use in our society. We all speak Languages. We all imbibe Cultures. Language expresses a particular meaning that represents the culture of a particular social group. We interact with a language and culture becomes its reference point.
Krober(1923) expresses, "Culture, then, began when speech was present, and from then on, the enrichment of either means the further development of the others". Hence, language and culture are complex, yet inseparable form of human interactions. Culture is complexly intertwined with language. Human interactions are defined as communication. The communicative force of culture works not only in representing aspects of reality, but also in connecting one context with another.
According to the linguistic relativity principle, the way we think about the world, gets influenced by the language we use to express it and vice versa. Therefore, consciously or unconsciously, we show certain behaviors and carry certain language habits which are deeply rooted in our culture. Thus learning a language means learning and adopting that culture.
This paper deals with this very relationship of language and culture with a cross-cultural interaction, how teaching and learning a foreign language plays a role in learning the target culture. This paper will make recommendations for effective culture education in foreign language classroom to develop intercultural competence.