bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adsorpsi Logam Ni (II) pada Adsorben ‘Ramah Lingkungan’ Asam Humat Kotoran Kuda
Authors: Rohmatullaili Rohmatullaili 
Published: December 2020

<p>Ekstraksi asam humat dari kotoran kuda telah dilakukan dengan prosedur standar International Humic Substance Society (IHSS) di bawah atmosfer udara. Penelitian ini dilakukan untuk memanfaatkan asam humat kotoran kuda (AHKK) sebagai adsorben limbah logam Ni (II). Dugaan awal adanya Asam Humat dalam kotoran kuda dikarenakan kandungan lignin di dalamnya. Persentase ekstraksi asam humat murni dari kotoran kuda mencapai 0,4%. Interaksi AHKK dengan logam Ni(II) dilakukan dalam larutan. Aspek adsorpsi yang dipelajari meliputi pengaruh pH, waktu kontak, kinetika, kapasitas adsorpsi, dan model isoterm adsorpsi Asam Humat Kotoran Kuda terhadap logam Ni (II). Adsorpsi logam Ni (II) pada AHKK mengikuti model isoterm adsorpsi Langmuir. Hasil penelitian menunjukkan bahwa Asam Humat dapat diekstraksi dari kotoran kuda, dan dapat mengadsorpsi logam Ni (II) pada situs aktifnya. Adsorpsi yang terjadi hanya pada lapisan tunggal, yang berarti situs aktif pada permukaan adsorben memiliki kemampuan adsorpsi yang sama dan terdistribusi secara merata.</p><p><em><br /></em></p>
Studi Density Functional Theory (DFT) Pengaruh Co-doping Zn dan N pada TiO2 Anatas
Authors: Shofiyullah Muhammad , Udaibah Wirda , Fitriani Ika Nur 
Published: December 2020

<p>Titanium dioksida (TiO<sub>2</sub>) merupakan salah satu bahan yang menjanjikan yang memenuhi persyaratan fotokatalis. Penelitian ini mempelajari pengaruh doping Zn dan N pada struktur geometri dan elektronik TiO<sub>2</sub> anatas. Untuk mengetahui struktur dan proses kinerja fotokatalitik digunakan perhitungan <em>density functional theory</em> (DFT) dengan algoritma generalized <em>gradient approximation</em> (GGA) menggunakan parameterisasi Perdew-Burke-Ernzerhof (PBEsol). Perhitungan struktur elektronik menggunakan parameter Hubbard <em>U</em>. Setelah optimasi terjadi distorsi volume kisi doping Zn 1,011 Å, doping N 1,209 Å dan co-doping Zn-N 1,646 Å. Data tersebut menunjukkan bahwa doping dapat mempengaruhi perubahan struktural. Perhitungan struktur elektronik menghasilkan celah pita TiO<sub>2</sub> murni sebesar 3,18 eV, kemudian terjadi penyempitan celah pita yang disebabkan oleh dopan. Celah pita doping Zn 2,9 eV, doping N 2,78 eV dan co-doping Zn-N 2,74 eV. Struktur elektronik baru hasil doping tidak hanya menyebabkan penyempitan celah pita tapi juga dapat menghambat rekombinasi pasangan elektron-hole, secara signifikan dapat meningkatkan aktivitas fotokatalitik TiO<sub>2</sub> di daerah cahaya tampak.</p>
Analisis Kualitas Air pada Reservoir PDAM Kota Semarang Menggunakan Uji Parameter Fisika, Kimia, dan Mikrobiologi, serta Dikombinasikan dengan Analisis Kemometri
Authors: Rohmawati Yunita , Kustomo Kustomo 
Published: December 2020

<p>Air menjadi kebutuhan yang sangat penting untuk kehidupan manusia. Perusahaan Daerah Air Minum (PDAM) Tirta Moedal merupakan Badan Usaha Milik Daerah (BUMD) Kota Semarang yang memberikan pelayanan air bersih dan air minum kepada warga masyarakat Kota Semarang. Tujuan dari penelitian ini adalah untuk menganalisis kualitas air pada parameter fisika, kimia, dan mikrobiologi pada enam titik lokasi reservoir di Kota Semarang kemudian hasilnya dibandingkan dengan standar baku mutu air bersih dan minum sesuai dengan Peraturan Menteri Kesehatan No.416/Menkes/Per/IX/1990 Tentang Persyaratan Kualitas Air Bersih dan Peraturan Menteri Kesehatan Republik Indonesia No.492/Menkes/Per/IV/2010 Tentang Persyaratan Kualitas Air Minum. Hasil penelitian menunjukan semua reservoir memenuhi standar baku air bersih. Berdasarkan hasil analisis kemometri menggunakan uji t satu sampel diperoleh bahwa t<sub>hitung </sub>&lt; t<sub>tabel</sub> atau 1.72 &lt; 2.57 dengan taraf signifikansi 95%, maka disimpulkan bahwa H<sub>o</sub> diterima dan Ha ditolak, atau tidak ada perbedaan kualitas air pada ke-enam reservoir PDAM Tirta Moedal Kota Semarang dengan standar baku mutu air yang ditetapkan pemerintah (µ = standar baku mutu).</p>
Behaver and risk factors for health of operators employed in oil production and preparation enterprises
Authors: Latyshevskaya N. I. , Mirochnik V. V. , Davydenko L. A. 
Published: December 2020

Objective: to evaluate the behavioral risk factors of the workers of the primary oil refining workshop with the aim of using them as a tool for substantiating management decisions and forming vectors of preventive measures.Materials and methods: the method of active survey investigated the prevalence of behavioral risk factors among operators in two age groups (20 – 35 and 36 – 60 years old).Results: the main vectors of behavioral risks for operators of different age groups were established: lack of motor activity, smoking, low medical activity, low perception of behavioral risks. Violations of lifestyle are predominantly combined (violations by 2 – 4 indicators). For older operators are more characterized by low motor and medical activity, disturbances in diet, an overestimation of the degree of influence of environmental and occupational factors on health when the significance of individual behavior is underestimated.Conclusions: Social policy at the enterprise should take into account the main vectors of behavioral risks, lower motivation and the implementation of a healthy style of behavior typical of older workers.
Relationship of the damage level of cell genetic apparatus with reproductive health disorder degree under conditions of harmful production
Authors: Morgul E. V. , Belik S. N. , Avetisyan Z. E. , Kvasov A. R. , Chebotareva Yu. Yu. , Evdokimova E. P. , Morgul A. R. 
Published: December 2020

Purpose: to determine the relationship of the damage level of cell genetic apparatus with reproductive health disorder degree under conditions of harmful production.Materials and methods: the study involved 36 poultry farm female workers of childbearing age. The first group was made up by 22 workers of the main production. The control group included the other 14 employees who were administrative and managerial personnel. Clinical statistical study of reproductive health was carried out with simultaneous investigation of the cariological indices of buccal epithelium using a fluorescence microscope. At least 1000 cells in a monolayer were analyzed on each micropreparation. Statistical data analysis was made using Statistica 6.0.Results: in workers of the main production, there was a high spread of inflammatory gynecological diseases (90.9 % versus 57.1 % in the control group), uterine fibroids (9.1 %, versus 7.1 %). At the same time a statistically significant increase in the number of cells with micronuclei was revealed in this group by 2.6 times (p < 0.05), with protrusions by 1.8 times (p < 0.05), an increase in the total proliferation index by 2.3 times (p < 0.05), and the two-nuclear cells made the greatest contribution to these differences. The integral indicator of cytogenetic disorders of women of the 1st group was also significantly higher by 2.0 times (p < 0.05). Conclusion: negative influence of factors of poultry house production environment on cell genome stability disturbance was revealed. It has been established that the reproductive health disorder degree has a direct proportional dependence on the damage level of cell genetic apparatus.
Heart rate variability in patients with stable angina pectoris as a risk factor for adverse clinical prognosis: relationship with affective depressive symptoms
Authors: Lobe A. O. , Chebotova A. I. , Ivanchenko D. N. , Dorofeeva N. P. , Pleskachev A. S. , Radchenko E. Yu. , Shlyk S. V. 
Published: December 2020

Objective: to investigate the heart rate variability (HRV) parameters of patients with a stable angina pectoris depending of presence depressive disorders; to identify the influence of affective symptoms on the clinical outcome during 12 months of observation.Material and methods: there are 121 male patients included in research with a stable angina pectoris II – III functional classes, hospitalized for a drug treatment and planned percutaneous coronary intervention (PCI) with stenting. The severity of affective symptoms and HRV are being assessed.Results: patients with depressive symptoms in the conservative treatment group had low SDNN level; patients with psychoemotional disorders in the surgical treatment group had differences by all HRV parameters (SDNN, SDANN, SDNN, rMSSD pNN50). Clinically unfavorable outcome, including intermediate points such as increase in angina attacks, re-hospitalization, stent’s restenosis, were mostly registered during 12 months of observation in the groups with affective symptoms.Conclusions: presence of depressive symptoms of patients with stable angina pectoris is accompanied with low HRV parameters, which is connected with worsening of cardiac prognosis.
Cytokine status disorders in children with urticaria
Authors: Maltsev S. V. , Sizyakina L. P. , Lebedenko A. A. , Pampura A. N. 
Published: December 2020

Objective: to study the state of cytokine status in children with acute and chronic urticaria.Materials and methods: 264 children of both sexes aged from 6 to 16 years with different variants of urticaria were examined. Clinical research methods included analysis of anamnestic data, objective examination of the child to determine the severity of urticaria. Immunological research methods included determination of IL-4, IL-6, IL-17, and IFN-γ levels by the method of enzyme immunoassay of blood serum.Results: cytokine profile analysis revealed hyperproduction of IL-17, γ-IFN with reduced IL-4 synthesis in children with acute urticaria. In children with chronic urticaria, IL-6 hyperproduction is noted against the background of a significant decrease in IL-4 synthesis.Conclusion: there was a significant relationship between the development of severe acute urticaria and the levels of proinflammatory cytokines IL-6, IL-17, and between the formation of chronic urticaria and the level of IL-6.
The effect of renin-angiotensin system blockers on aldosterone levels in patients with chronic heart failure with preserved ejection fraction
Authors: Shevelok A. N. 
Published: December 2020

Objective: to evaluate the effect of renin-angiotensin-aldosterone system (RAAS) blockers on aldosterone level in patients with chronic heart failure with preserved ejection fraction (HFpEF).Materials and methods: the prospective study included 158 patients (58 men and 100 women, mean age 62,3 ± 7,4 years) with HFpEF (> 50 %) and left ventricular diastolic dysfunction. All patients had no history of primary aldosteronism and did not use the mineralocorticoid receptor antagonists during the last 6 weeks. We evaluated the duration of treatment with angiotensin-converting enzyme (ACE) inhibitors or angiotensin-2 receptor antagonists (ARA-2) and its average daily dose. The dose of RAAS blockers was assessed during previous 6 months as a percentage of target. Aldosterone plasma concentration was measured and the normal level was 40 – 160 pg/ml.Results: according to laboratory results 99 patients (62,7 %) had normal aldosterone level (nAld) and 59 patients (37,3 %) had high aldosterone level (hAld). hAld patients had significantly higher duration of RAAS blockers treatment (6 (3; 8) versus 4 (2; 5) years, p < 0,001) and dose (50 (25; 50) % vs 25 (12,5; 50) % of target, р=0,01). Multiple regression analysis showed that after standartization for age, severity of HFpEF, duration of arterial hypertension and comorbidity only long-term (more than 5 years) treatment with RAAS blockers remained the independent risk factor of high aldosterone level (odds ratio 3,16, 95 % confidence interval 2,08 – 8,24).Conclusions: in HFpEF patients’ plasma aldosterone level is closely associated with RAAS blockers treatment. Long-term (more than 5 years) therapy with ACE inhibitors or ARA-2 is the independent risk factor of secondary hyperaldosteronism.
A rare case of type i glutaric aciduria in an early child
Authors: Lebedenko A. A. , Berezhanskay S. B. , Todorova A. S. , Vostrykh N. N. , Kaushanskay E. Y. , Lukyanova E. A. , Papsheva E. A. , Smykova G. N. , Taranenko L. N. 
Published: December 2020

Glutaric aciduria type I (deficiency of glutaryl-COA dehydrogenase, glutaric acidemia type I) is a rare autosomal recessive disease caused by mutations in the gene encoding the enzyme glutaryl – COA - dehydrogenase (GCDH). Cerebral organic aciduria, caused by a deficiency of glutaryl-COA - dehydrogenase, is generally considered a neurological disorder.The phenotypic spectrum of untreated GA-1 varies from a more common and pronounced form (a disease with infancy) to a low-symptom and less common form. In people with the same genotype, the clinical manifestations and depth of CNS damage can vary widely depending on the age of manifestation of acute encephalopathic crises. It is assumed that with early detection and treatment of “asymptomatic” newborns (in the context of screening for this disease), most people who would have developed manifestations of GA-1 with childhood or late onset will remain asymptomatic.
Some features of the epidemic spread of the new coronavirus infection (COVID-19) in the Rostov Region
Authors: Kovalev E. V. , Slis S. S. , Yanovich E. G. , Pichurina N. L. , Volovikova S. V. , Gaevskaya N. E. , Chemisova O. S. , Karpushchenko G. V. , Litovko A. R. , Noskov A. K. 
Published: December 2020

Purpose: to analyze the epidemiological situation for a new coronavirus infection (COVID-19), to identify some regional features of the Rostov region that contribute to spread of infection.Materials and methods: when assessing the epidemiological situation for a new coronavirus infection in the Rostov region, we used information provided by the Department of the Federal service for supervision of consumer protection and human welfare in the Rostov region. Processing of statistical data was performed by means of generally accepted method.Results: the spreading of a new coronavirus infection in the Rostov region is uneven in nature. When differentiating the territories of the region we identified groups of municipalities with a very high, medium and low number of patients. The administrative territories division of the Rostov region into the “Rostov urban agglomeration” and cluster of municipalities in which pronounced factors and conditions determining the “pendulum” migration of the population are absent, allow analyzing the specific features of the region and identification of territory with the highest risk of epidemic process intensification of a new coronavirus infection.Conclusions: the carried out differentiation of municipalities made it possible to identify and analyze some territorial features of the Rostov region, contributing to the spread of a new coronavirus infection. The obtained results could be used for development of measures aimed at reducing intensification of the epidemic process COVID-19 in condition infection.
Rationale of specialized medical care for patients with chronic heart failure in the Russian Federation
Authors: Fomin I. V. , Vinogradova N. G. 
Published: December 2020

Objectives:to determine the causes of ineffective observation and poor prognosis in patients undergoing ADHF, in real clinical practice and to consider the basics of the formation of specialized medical care for patients with heart failure (HF).Materials and methods:the study was conducted based on the City Center for the treatment of heart failure (center HF), N. Novgorod. The study consistently included 942 patients with heart failure (HF) at the age of 18 years and older who underwent ADHF and received inpatient treatment in center HF between March 4, 2016 and March 3, 2017. Based on the decisions of patients to continue outpatient monitoring in center HF, two groups of patients were distinguished: patients who continued to be monitored in center HF (group I, n = 510) and patients who continued to be monitored in outpatient clinics at the place of residence (group II, n = 432). The assessment of adherence to treatment, overall mortality, survival and re-admission to a depth of two years of observation was carried out. Statistical data processing was performed using Statistica 7.0 for Windows and the software package R.Results:all patients in the study groups had high comorbidity. Group 2 patients turned out to be statistically significantly older, more often had III functional class (FC) HF, lower the baseline test score of 6-minute walk, and higher the baseline clinical assessment scale. After 2 years of follow-up in group II, there was a significant deterioration in adherence to basic therapy of HF compared with group I. According to the results of multifactorial proportional risk Cox models, it was shown that observation of patients in the group 1 is an independent factor increasing the risk of overall mortality by 2.8 times by the end of the second year of observation. Survival after two years of follow-up was: in group I — 89.8 %, and in group II — 70.1 % of patients (OR = 0.3, 95 % CI 0.2 – 0.4; p1/2 < 0.001). After two years of follow-up, the proportion of re-hospitalized patients in group II was greater (78.0 % of patients) versus group 1 (50.6 % of patients, OR = 3.5, 95 % CI 2.6 – 4.6; p1/2 <0.001). The independent risk of re-hospitalization according to multinominal logit regression was 3.4 times higher in group II and 2.4 times for III – IV FC HF.Conclusions:the inclusion of patients with HF in the system of specialized medical care improves adherence to treatment, prognosis of life and reduces the risk of repeated hospitalizations. Patients of an older age and with an initially greater clinical severity refused specialized supervision in center HF.
High-frequency electrocardiography as an additional method for diagnosing myocardial ischemia in patients with СHD of various ages
Authors: Kolosova K. S. , Grigoreva N. Y. , Kosuga Y. I. 
Published: December 2020

Objectives: to study the relationship between high-frequency electrocardiography (ECG) and selective coronary angiography data.Materials and methods: the study was conducted on 125 patients with a diagnosis of coronary heart disease (CHD), who were sent for selective coronary angiography. Patients were divided into groups: I group - young age, II group 2- middle age, III group — senile and elderly age. All patients were recorded high-frequency ECG in 12 common leads using a computer electrocardiograph, the data obtained were analyzed by special software.Results: according to the selective coronary angiography data, hemodynamically insignificant lesions of the coronary arteries were present in 34 (27.2%) people, and in 49 (39.2 %) people - hemodynamically significant lesions of the coronary arteries. Hemodynamically significant coronary artery stenoses are more often detected in elderly and senile patients. Stenotic lesions of the coronary arteries were more common in group 3 as opposed to group 2 (p = 0.002). High-frequency ECG analysis revealed a significant difference in the amount of RAZ between elderly and senile patients compared to young and middle-aged patients (p 1–2 = 0.373; p 1–3 = 0.006; p 2–3 = 0.008). The RAZ parameter of a high-frequency ECG in 12 common leads has a relationship with the age of patients, the number of coronary arteries with stenotic lesions, and the number of hemodynamically significant stenoses.Conclusion: the results of the study show that high-frequency ECG can be further developed as an additional method for diagnosing myocardial ischemia.
Influence of dosed walking on the course of arterial hypertension in patients with chronic obstructive pulmonary disease
Authors: Kryuchkova O. N. , Bubnova M. A. , Bubnov S. E. 
Published: December 2020

Objective: to study the influence of dosed walking on the course of hypertension and quality of life in patients with chronic obstructive pulmonary disease.Materials and methods: the study included 85 patients with a combination of arterial hypertension and chronic obstructive pulmonary disease, with an average age of 60.9 ± 1.06 years. Group A patients were prescribed dosed walking in addition to medication, while group B patients received only antihypertensive medications, statins, and basic treatment for chronic obstructive pulmonary disease. The effectiveness of treatment was determined after 6 weeks based on a standard examination, daily monitoring of blood pressure and ECG, and quality of life indicators. Long-term results were evaluated after 6 months.Results: patients whose treatment plan included physical training, in contrast to patients receiving only medication, noted a decrease in complaints of headache (p=0.034), dizziness (p=0.041), tachycardia (p=0.029), general weakness (p=0.003), head noise and tinnitus (p=0.018), sleep disturbance (p=0.010) and shortness of breath (p=0.004). They had normalization of all indicators of quality of life according to the SF-36 questionnaire: scales physical functioning (p<0.001), role functioning due to physical condition (p<0.001), pain intensity (p<0.001), general health (p=0.002), vital activity (p=0.001), social functioning (p=0.013), role functioning due to emotional state (p<0.001), mental health (p=0.008), physical component of health in general (p<0.001) and the mental health component (p=0.002). Improvement of well-being was accompanied by normalization of lipidogram indicators, daily heart rate and blood pressure: reduction of average daily indicators of blood pressure (p<0.001), pressure load index (p<0.001), blood pressure variability (p<0.05), pulse pressure (p<0.001) and the rate of morning rise in blood pressure (p<0.001).Conclusion: addition to standard medical therapy of dosed walking has a positive effect on the course of arterial hypertension in patients with chronic obstructive pulmonary disease.