bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contenidos de enseñanza de fracciones en 6to de primaria, México: Un análisis interconductual
Authors: Hernández-Rodríguez César , Bazán-Ramírez Aldo 
Published: July 2020

El presente trabajo tuvo por objetivo analizar desde la taxonomía de Ribes y López (1985), los contenidos de la enseñanza de fracciones matemáticas en sexto grado de primaria. A partir de los aprendizajes esperados propuestos en los planes y programas para trabajar fracciones, además de realizar una revisión del libro de desafíos matemáticos 6to grado, se identificaron los ejercicios que los estudiantes tienen que realizar al trabajar con el tema de fracciones. Posterior a la revisión, se clasificaron los contenidos de acuerdo con la taxonomía funcional. Partiendo de la idea que las matemáticas se deberían trabajar desde niveles sustitutivos, al contar con su propio medio de contacto convencional, se pretendía encontrar actividades que promovieran dicho nivel de desligamiento funcional. Como principales resultados se encontraron: 1. Las actividades que promueven los libros no están de acuerdo con los aprendizajes esperados planteados en los planes y programas, 2. Las actividades en el libro de texto, así como los aprendizajes esperados resaltados en el plan y programa de estudios, corresponden a actividades de enseñanza y de aprendizaje de niveles más simples de desligamiento funcional de acuerdo con la taxonomía funcional asumida. Estas actividades en su mayoría de tipo procedimental, correspondería a un nivel de desligamiento de tipo suplementario.
Provisional selves, revolving teams & temporary workspaces
Authors: Dunston Emelia 
Published: July 2020

When you look at the division of staff responsibilities among student affairs units at most midsize to large institutions, you will see that many professionals have adopted a specialist persona. This is a common outcome found with the organizational structures used within student affairs. The overlap of roles and responsibilities does not occur, leading to silos. Silos perpetuate isolation, discourage collaboration, and make advancement difficult for professionals. To help our field combat this problem, we need to structure our units to develop professionals into generalists. Blending concepts developed by Ancona & Bresman (2007) and Petriglieri, Petriglieri & Wood (2017), this paper proposes a new workplace model for student affairs professionals that encourages the formation of provisional selves, revolving teams and temporary workspaces.
Tennessee Education Savings Account: Tipping the Scales From Equity to Choice
Authors: Curtin Erin 
Published: July 2020

This article provides an analysis of Tennessee’s newly signed Education Savings Account policy, a school choice initiative. The policy provides vouchers, in the form of a debit card, to students in grades K-12 who are at or below 200% of the federal poverty line and are zoned to attend a Nashville, Shelby County, or Achievement School District school. Using the Policy Window Framework the author uncovers that the policy was created in a federal and state-level political convergence, which attempted to place equity at the forefront of the issue. However, using Levin's Comprehensive Education Privatization Framework, we can see that neoliberal ideals of choice and efficiency conquer equity in the finalized policy. The author predicts the outcomes of this new policy using this framework in tandem with 3 case studies: Louisiana Scholarship Program, DC Opportunity Scholarship Program, and Tennessee’s Individualized Education Accounts.
Culturally Responsive Pedagogy in Mathematics
Authors: Nagasawa Kenta 
Published: July 2020

Purpose: This paper is a thematic literature review to examine the current state of research about Culturally Responsive Pedagogy in mathematics. The main themes are students’ perception, teacher education for pre-service teacher and professional development for teachers.
Research methods/ approach: Literature was collected from Eric, which is a research engine of the education field. Also, Google Scholar is used to find articles of major scholars introduced by Dr. Rich Milner, who is the instructor of this course.
Findings: Students faced microaggressions in mathematics class, which discouraged them to learn mathematics. The effect of teacher education was inconsistent in terms of the awareness of culturally responsive pedagogy and lesson plans. Research of professional development mentioned that mathematics was cultural.
Implications for research and practice: It is more interesting to conduct long term or follow-up research to find the teacher’s practice after a taking professional development program. Also, it is critical to expand research scope besides African American and Latino students. Finally, evidence-based research is needed to change the political situation.
Keywords: culturally responsive teaching, mathematics, teacher education, professional development, student’s perception
Analyzing Patterns of Qualified Teachers and the Impact of Teacher Education Requirements in Small Island Developing States
Authors: Jurewicz Nicole , Yeldell Jasmyne 
Published: July 2020

This paper analyzes existing patterns in the percentage of qualified teachers in primary school in Small Island Developing States (SIDS) as well as patterns in the current required minimum level of education to teach primary school in those countries. Sustainable Development Goal Target 4.C aims to substantially increase the supply of qualified teachers by 2030, including through international cooperation for teacher training in developing countries, especially least developed countries and Small Island Developing States. Using data from the World Policy Centre and the World Bank, this study finds that in a sample of Small Island Developing States (N = 23) the percentage of teachers who are qualified is lower than the global average (78.1 percent compared to 85.6 percent). When looking at minimum teacher educational requirements for primary education, only 29.2 percent of countries require a Bachelor's degree with training (compared to 48.8 percent globally). This study further aimed to determine whether stricter educational requirements for primary school teachers in SIDS is related to higher literacy rates of ages 15-24 and GDP per capita. No significant relationship between educational requirements and either measure was found using a Pearson’s product-moment correlation coefficient. However, in a global sample (N = 168), a significant positive correlation between teacher educational requirements and GDP was found. In addition, a marginally significant positive correlation between educational requirements and literacy rate ages 15-24 was found. The results suggest that having qualified teachers and stricter educational requirements may lead to economic and educational benefits, though the results from SIDS-only analyses were inconclusive. This paper also recommends for changes in policy in order to achieve Sustainable Development Goal 4.C, including the development of a clearer universal definition of qualified teacher and the development of programs to help individuals attain teaching credentials and higher education.
Revisiting a Long-Lasting Legacy
Authors: Zhang Shiqing 
Published: July 2020

This review of literature will address the influences of knowledge of Chinese characters on the reading development of English. This question stems from an increasing number of children of Chinese heritage enrolling in school in the U.S. who wish to gain biliteracy in English and Chinese. On the one hand, bilingualism is acknowledged to be beneficial to young readers’ language and cognitive development. However, on the other hand, the logographic nature of Mandarin Chinese makes it difficult for many educators in the country who only know alphabetic languages like English and Spanish to understand how Chinese-English bilingual readers reconcile two different systems and envision what support they may need.
This review will primarily focus on the basics of Mandarin Chinese and developmental models of the two languages to examine how proficiency in Chinese can transfer to and facilitate the reading development of English. Departing from the comparison and contrast between linguistic features and developmental models of the two languages, this review will investigate contributions of Chinee characters to English word reading at the levels of cognition, morphology, and phonology. While Chinese characters as logograms demand predominantly morphological knowledge than phonological awareness from readers, it is phonological awareness that contributes most to reading English words among beginning readers in kindergarten and first grade.
Clinical trials for cellular therapy products: conclusions reached by foreign regulatory bodies
Authors: Melnikova E. V. , Merkulova O. V. , Merkulov V. A. 
Published: July 2020

Currently, the problem of adopting viable human cell-based drugs – biomedical cell products (BCPs) – in medical practice in the Russian Federation includes, among others, lack of experience in clinical trials for such drugs and insufficient expert assessment under the national state registration procedure. In global practice, by the beginning of 2020, there were over 30 cellular therapy products (human cellular- and tissue-based products) known to have undergone clinical trials for sales licenses from regulatory bodies in the United States, European Union, Japan, and South Korea. Most cellular therapy products are intended for treatment of severe orphan diseases and lifethreatening conditions that currently cannot be treated by traditional drugs or methods. The aim of this study is to analyze the global experience in clinical trials for cellular therapy products and also to examine conclusions reached by regulatory authorities with regards to issuance of sales licenses for the products. Particular attention was paid to clinical trials that subsequently led to granting of sales license (state registration). In reviewing such trials, we also focused on the types and number of clinical trials, the number of patients involved in the clinical trials, conclusions made by expert regulatory agencies on the efficacy, safety and risk/benefit ratio. Most of the products were approved for use based on uncontrolled phase II clinical trials. In the clinical trial, apart from the historical group and the placebo-controlled group, there was also a control group that received nothing. The number of patients in most clinical trials was limited, especially for drugs intended for treatment of rare genetic diseases, as well as drugs approved for use in Japan.
Use of peroxiredoxin for preconditioning of heterotopic heart transplantation in a rat
Authors: Grudinin N. V. , Bogdanov V. K. , Sharapov M. G. , Bunenkov N. S. , Mozheiko N. P. , Goncharov R. G. , Fesenko E. E. , Novoselov V. I. 
Published: July 2020

Peroxiredoxin 6 (Prdx6) is an antioxidant enzyme in the human body that performs a number of important functions in the cell. Prdx6 restores a wide range of peroxide substrates, thus playing a leading role in maintaining redox homeostasis in mammalian cells. In addition to peroxidase activity, Prdx6 has an activity of phospholipase A2, thus taking part in membrane phospholipid metabolism. Due to its peroxidase and phospholipase activity, Prdx6 participates in intracellular and intercellular signal transmission, thereby facilitating the initiation of regenerative processes in the cell, suppression of apoptosis and activation of cell proliferation. Given the functions performed, Prdx6 can effectively deal with oxidative stress caused by various factors, including ischemia-reperfusion injury. On an animal model of rat heterotopic heart transplantation, we showed the cardioprotective potential of exogenous recombinant Prdx6, introduced before transplantation and subsequent reperfusion injury of the heart. It has been demonstrated that exogenous Prdx6 effectively alleviates the severity of ischemia-reperfusion injury of the heart by 2–3 times, providing normalization of its structural and functional state during heterotopic transplantation. The use of recombinant Prdx6 can be an effective approach in preventing/alleviating ischemia-reperfusion injury of the heart, as well as in maintaining an isolated heart during transplantation.
The prevalence of wide QRS complex (≥110 ms) among the population, depending on sex, age and place of residence
Authors: Muromtseva G. A. , Vilkov V. G. , Shalnova S. A. , Konstantinov V. V. , Deev A. D. , Evstifeeva S. E. , Balanova Yu. A. , Imaeva A. E. , Kapustina A. V. , Karamnova N. S. , Shlyakhto E. V. , Boytsov S. A. , Nedogoda S. V. , Shabunova A. A. , Chernykh T. M. , Belova O. A. , Indukaeva E. V. , Grinshteyn Yu. I. , Trubacheva I. A. , Efanov A. Yu. , Astakhova Z. T. , Kulakova N. V. 
Published: July 2020

Aim. To assess the prevalence of wide QRS complex (≥110 ms) among the population, depending on sex, age, place of residence (urban or rural area), the presence of obesity and cardiovascular disease.Material and methods. The analysis was based on the ESSE-RF study (n=17,364, men — 38%). Twelve-lead resting electrocardiography (ECG) data from the regions participating in the study were analyzed according to the Minnesota code manual. Patients were divided into groups of QRS <110 ms and ≥110 ms (wide QRS).Results. QRS groups did not differ in heart rate and age. The prevalence of wide QRS complex in the population amounted to 17,2%. Men were likely to have wide QRS than women (18,5% and 16,2%, respectively, p<0,0005) due to the increased frequency of “preblock” QRS duration (110-119 ms; 12,3% vs 10,9%, respectively, p<0,025). The prevalence of QRS≥120 ms in the sex groups was the same, almost 7%. The prevalence of widened QRS in the population significantly exceeded other unfavorable prognostic ECG indicators, such as major ECG abnormalities, conduction disorders, abnormal Q wave (QS). The prevalence of wide QRS complex increased with age from 11,1% to 19,2, (p<0,001). The highest increase in prevalence of wide QRS complex was observed after 55 years; nondynamic periods were recorded in men from 25, and in women from 35 to 54 years. In contrast to women, the prevalence of wide QRS in men did not depend on the place of residence (18,6% in urban and 18,3% in rural areas); in rural women this parameter was observed as often as in men. This may indicate a more severe epidemiological situation of car - diovascular disease in rural residents. Obesity, high blood pressure, and a history of coronary artery disease were more common in the group of wide QRS complex.Conclusion. For wide QRS complex, the same age and sex relationships are cha - racteristic as for the basic routine ECG indicators. The prevalence of wide QRS in the population exceeds major ECG abnormalities, conduction disorders, abnormal Q wave (QS). In rural residents, the increased prevalence of wide QRS is probably due to the greater prevalence of obesity and hypertension.
Efficacy and safety of statin therapy in multimorbid outpatients with very high cardiovascular risk
Authors: Izmozherova N. V. , Popov A. A. , Bakhtin V. M. 
Published: July 2020

Aim. To analyze the efficacy and safety of statin therapy in multimorbid outpatients with very high cardiovascular risk in actual clinical practice.Material and methods. The study included 131 patients with an established very high cardiovascular risk. History and anthropometric data were collected. The Charlson Comorbidity Index (CCI) was calculated; patients were divided into groups of moderate (№ 1, ≤6 points) and high (№ 2,> 6 points) multimorbidity. The frequency of prescribing statins, the range of doses used, the achievement of lipid metabolism targets, and the incidence of adverse effects were evaluated.Results. The median of the CCI was 6 (5÷8) points. Group 1 included 72 patients, group 2 — 59 patients. Statins received 87 (66,4%) patients, more often in group 1 (n=54) than 2 (n=33), p=0,026. The minimum doses were taken by 17 patients, the mean — 66, the maximum — 4. Patients of group 2 received higher dosages (χ2 =9,3, p=0,010). The target level of total cholesterol was achieved in 8 (6,1%) patients, low-density lipoprotein cholesterol — no one (0,0%). Of the 106 patients ever taking statins, they were withdrawn in 19 (17,9%) patients. The reason for discontinuation in 7 patients were adverse effects, in 5 — the high cost of therapy; in 7 patients, the reason was identified. Adverse effects were recorded in 12 (11,3%) patients; there were no differences between groups (p=0,118).Conclusion. Patients with a very high cardiovascular risk are characterized by high multimorbidity. Statins are less commonly prescribed for patients with severe polymorbidity, but at higher doses. Despite the sufficient prescribing statins and the use of mean doses, target lipid levels were not achieved. The presence of multimorbidity was not associated with an increase in the incidence of statin adverse effects.
The results of using lean technologies in assessing the cardiovascular risk based on ultrasound markers of atherosclerosis
Authors: Tsukanova E. I. , Aleksanin S. S. 
Published: July 2020

Aim. To establish the practical value of studying ultrasound markers of atherosclerosis for assessing cardiovascular risk as a part of screening of the population based on lean technologies.Material and methods. The study included 305 patients. The age of participants ranged from 31 to 84 years, the median age was 61,0 years. The object of study was 1830 extracranial vessels, including common carotid arteries, internal carotid arteries, subclavian arteries. Duplex ultrasound was using an Acuson 2000 ultrasound system with a frequency of 3-9 MHz. An abbreviated ultrasound protocol was used. The obtained data were processed using the software package Statistica 12.0 (StatSoft, USA).Results. As a result of lean technology application, the duration of procedure was significantly reduced, and the process was improved by 6 times. Changes in intimamedia thickness (IMT) were detected in 42,6% of cases, and significantly more changes in IMT were found in women (48,1%) than in men (25,0%), p=0,0005. Atherosclerotic plaques (ASP) were detected in 53,4% of cases (men — 68,1%; women — 48,9%), p=0,0043. In men <50 years of age, a more intense increase in ASP prevalence than in women was recorded. Starting from 50 years old, ASP prevalence has leveled off. The prevalence of carotid atherosclerosis at any age was higher in men. From the age of 50, sex differences had no significance, p=0,133. In 87,1% of cases, ASP was located within the bifurcation. In the studied groups, obstruction to 50% were more common (46,2%, p=0,0005). Questioning revealed that over the past three years, duplex ultrasound was performed in 21% of patients. Satisfaction with the quality of the procedure was 57,0% (174/305).Conclusion. The results of the study indicate the high practical value of ultrasonic markers of atherosclerosis using abbreviated ultrasound protocol as a part of screening of the population. The inclusion of noninvasive vascular imaging data in screening programs will help to achieve targets for reducing cardiovascular mortality and personalize the assessment of cardiovascular risk.
Parameters of stressful events at a young age (data of cross-sectional epidemiological studies)
Authors: Akimov A. M. 
Published: July 2020

Aim. To determine the parameters of family and work stress in the open population of the medium urban city of Western Siberia among young men and women.Material and methods. The study of nonconventional (psychosocial) risk factors for coronary artery disease was carried out according to the WHO program “MONICA-psychosocial” using the standard “Knowledge and attitude to your health” questionnaire. Family and work stress was determined by a face-to-face interview.Results. Stress in the family among young people in the medium urban city of Western Siberia was manifested mainly by the loss or severe illness of relatives, family conflicts; in men as well — a change in marital status, in women — lack of home rest. Stress at work was manifested mainly in high or low workplace responsibility; in men as well — in changing occupation, increasing workload and responsibility over the past year, changing job, in women — in the change of manager, lack of home rest among working women.Conclusion. Consequently, the sex characteristics of psychosocial risk factors for cardiovascular diseases, regarding chronic social stress factors, are even more significant, which specifies the need for a further study of psychosocial factors, and thereby the possibilities for changing the epidemiological situation of cardiovascular diseases in region. This also confirms the need for future research on the relationships of psychological disorders with cardiovascular diseases.
The effect of aerobic exercise on muscle tissue in patients with severe heart failure and normal body weight
Authors: Galenko V. L. , Lelyavina T. A. , Sitnikova M. Yu. , Yukina G. Yu. , Bortsova M. A. , Dmitrieva R. I. 
Published: July 2020

Aim. To assess the response of skeletal muscle and myocardium to original aerobic exercise (AE) program in patients with heart failure (HF) with reduced ejection fraction (HFrEF); to assess morphometric changes in skeletal muscle fiber after AE.Material and methods. The study included 100 patients with class III HFrEF (age — 52±5,2 years; body mass index (BMI) — 23,5±2,8 kg/m2). At baseline and after 6 months of AE, an echocardiogram, peak oxygen uptake (VO2peak), exercise tolerance and quality of life (QOL) were evaluated. Lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) activity were evaluated in biopsy material of lower leg muscles.Results. After 6 months of AE, the left ventricular ejection fraction (LVEF) increased by 10,5±2,3%, QOL — by 24,8±3,5 points, exercise tolerance — by 9,7±0,5 points, VO2peak — by 5,2±0,5 ml/min/kg (p1,2,3,4< 0,05). In 6 patients, the diameter of muscle fiber decreased slightly. The activity of ALP (initially — 0,33±0,09 D) increased by 24,2% (p< 0,05); LDH in glycolytic fibers was initially 0,213±0,08 D, in oxidative fibers — 0,083±0,04, and after 6 months of AE, decreased by 24,4% and 6,0%, respectively (p1 <0,05, p2 >0,05). A positive relationship was found between the dynamics of HF class and fiber diameter (r=0,4, p=0,05); an increase in сardiopulmonary exercise test was associated with ALP activity (r=0,5, p=0,05).Conclusion. 1. Dosed aerobic exercise in patients with stable class III HFrEF, normal BMI, based on reaching the lactate threshold, had a positive effect on LVEF, QOL, exercise tolerance and VO2peak. 2. With exercise training, a decrease in fiber diameter and LDH activity in both oxidative and glycolytic fibers, an increase in ALP activity were revealed. 3. The functional relationship between the increase in exercise tolerance and ALP content in muscle tissue was revealed.