bluuebunny/crossref_metadata_2025_split huggingface dataset:
Direct incorporation of [18F] into Aliphatic Systems: A promising Mn-catalysed Labelling Technique for PET Imaging
Authors: Cesarec Sara , Robson Jonathan A. , Carroll Laurence S. , Aboagye Eric O. , Spivey Alan C. 
Published: September 2020

Background:
One of the challenges in positron emission tomography (PET) is labelling complex aliphatic
molecules.

Objective:
To develop a method of metal-catalysed radiofluorination that is site-selective and works in moderate to good
yields under facile conditions.

Methods:
Herein, we report on the optimisation of an aliphatic C-H to C-18F bond transformation
catalysed by a Mn(porphyrin) complex.

Results:
The successful oxidation of 11 aliphatic molecules including progesterone are reported. Radiochemical
Incorporations (RCIs) up to 69% were achieved within 60 min without the need for pre-activation or specialist equipment.

Conclusion:
The method features mild conditions (60 °C) and promises to constitute a valuable approach to labelling of
biomolecules and drug substances.
Synthesis of Nanostructured Lipid Carriers Loaded Chitosan/ Carbopol Hybrid Nanocomposite Gel for Oral Delivery of Artemether and Curcumin
Authors: Kumar Arun , Behl Tapan , Uniyal Toshi , Chadha Swati 
Published: September 2020

Background:
Antimalarial therapy remains the utmost effective means for the management
of malarial parasites in the liver and red blood cells. The application of these therapeutic agents
is hampered by their improper application, hepato-toxicity caused by their continuous use, and degradation
by hepatic enzymes.

Methods:
Recent advancements in drug delivery applications have shown potential in improving the
pharmacological properties of artemether. Nanostructured lipid carriers (NLCs) loaded chitosan
(CH)/Carbopol (CB) hybrid gel was prepared using glycerol monostearate (GMS) as solid lipid and
clove oil as a liquid lipid for artemether (ART) and curcumin (CR) for its localized effect on the liver.

Results:
The smaller particle size (~118 ± 1.0 nm) and high zeta potential (- 41.1 ± 6.46 mV) confirm
the formulation and stability of NLCs. On the other hand, the shape and morphology of prepared
NLCs and gel showed a spherical and wrinkled surface with a size range of 150-250 nm. The release
studies of the NLC’s showed a controlled release of artemether (~ 92%) and curcumin (~ 83%) for
up to 30 h. Photostability data showed that, approximately, ~86.5 ± 0.3% and ~60 ± 0.9% of nanoencapsulated
artemether and curcumin were still detected on exposure to sunlight, respectively. It has
been found from the permeation study that 69.8% and 49.1% of the drug was permeated across the
mucus membrane in 24 h with a significant increase (P < 0.05) in flux as well as permeability coefficients.

Conclusion:
The overall results showed that prepared CH/CB/NLCs hybrid gel could be a promising
vehicle for the effective delivery of ART and CR for the management of malarial parasites.
Lay Summary: Antimalarial therapy remains the utmost effective means for the management of malarial
parasites in liver and red blood cells. Recent advancements in drug delivery applications have
shown potential in improving the pharmacological properties of artemether. Application of these
therapeutic agents hampered by their improper application, hepato-toxicity caused by their continuous
use and degradation by hepatic enzymes. To manage the above issues, we synthesize nanostructured
lipid carriers (NLC’s) loaded chitosan (CH)/Carbopol (CB) hybrid gel using glycerol monostearate
(GMS) as solid lipid and clove oil as liquid lipid for artemether (ATR) and curcumin (CR) for
its local action in liver and the major criteria were to find a protective barrier with hepatoprotective
nature of the curcumin.
Impact of Job Involvement on In-Role Job Performance and Organizational Citizenship Behaviour
Authors: Chughtai Aamir Ali 
Published: September 2020

This study examines the impact of job involvement on the self-report measures of inrole job performance and organizational citizenship behaviour. The results of this study revealed that job involvement was positively correlated with both in-role job performance (r = 0.30, p<0.01) and OCB (r = 0.43, p<0.01). In addition to this it was found that organizational commitment partially mediated the job involvement performance relationship. Furthermore the findings of this research uncovered that job involvement exerted a stronger impact on OCB than on in-role performance. Finally the practical implications of this research for organizations are discussed.
Impact of Chronic Use of Antimalarials on SARS-CoV-2 Infection in Patients With Immune-Mediated Rheumatic Diseases: Protocol for a Multicentric Observational Cohort Study
Authors: Gomides Ana , Ferreira Gilda , Kakehasi Adriana , Lacerda Marcus , Marques Cláudia , Mota Licia , Paiva Eduardo , Pileggi Gecilmara , Provenza José , Reis-Neto Edgard , Sampaio Vanderson , Xavier Ricardo , Pinheiro Marcelo 
Published: September 2020

Background
COVID-19, caused by the virus SARS-CoV-2, has brought extensive challenges to the scientific community in recent months. Several studies have been undertaken in an attempt to minimize the impact of the disease worldwide. Although new knowledge has been quickly disseminated, including viral mechanisms, pathophysiology, and clinical findings, there is a lack of information on the effective pharmacological management of this disease. In vitro studies have shown some benefits related to the use of antimalarials (chloroquine and hydroxychloroquine) for inhibiting SARS-CoV-2. However, the data from open clinical trials on COVID-19 patients are controversial.

Objective
We present the protocol for a research project that compares the potential protective effect of antimalarials in preventing moderate-to-severe forms of COVID-19 in two groups: (1) patients treated chronically with antimalarials for rheumatic diseases and (2) other members of the patients’ household who have not been diagnosed with rheumatic diseases and are not taking antimalarials.

Methods
This is a 24-week, prospective, observational cohort study comprising patients from public and private health services across Brazil, who chronically use antimalarials for the treatment of immune-mediated rheumatic diseases, osteoarthritis, or chikungunya-related arthropathy. A total of six sequential phone interviews were scheduled during the COVID-19 outbreak in five different regions of Brazil. Information regarding social, epidemiological, and demographic data, as well as details about rheumatic diseases, antimalarials, comorbidities, and concomitant medication, is being recorded using a specific online form in the REDCap database. Symptoms suggestive of COVID-19, including fever, cough, dyspnea, anosmia, and dysgeusia, are being self-reported and collected via phone interviews. Our main outcomes are hospitalization, need of intensive care unit, and death.

Results
Recruitment began at the end of March 2020, and the inclusion was done during an 8-week period (from March 29 to May 17) with a total of 10,443 individuals enrolled at baseline, 5166 of whom have rheumatic diseases, from 23 tertiary rheumatology centers across 97 Brazilian cities. Data analysis is scheduled to begin after all inclusion data have been collected.

Conclusions
This study, which includes a large sample of chronic antimalarial users, will allow us to explore whether SARS-CoV-2 infection may be associated with immune-mediated rheumatic diseases and long-term antimalarial usage.

Trial Registration
Brazilian Registry of Clinical Trials RBR–9KTWX6; http://www.ensaiosclinicos.gov.br/rg/RBR-9ktwx6/

International Registered Report Identifier (IRRID)
DERR1-10.2196/23532
Aneka Fungsi Bahasa Syair- Syair Lagu Ismail Marzuki
Authors: Wijana I Dewa Putu 
Published: September 2020

This article intends to reveal various language functions consisted in Ismail Marzuki’s song lyrics in the frame of the widely known Jakobson’s language function theory. By using data gathered from various sources, the research findings shows that Ismail Marzuki’s song lyrics are dominated by the use of language which is exploited to bear poetic function in order to enable the audiences experiencing the song’s messages and other language functions aesthetically. All Marzuki’s song lyrics concern with extralinguistic world. Accordingly, it is not surprising that none of the song lyric is used to convey metalinguistic function for explaining the internal structure of a language.
Penulis Karya Ilmiah dan Copyediting
Authors: Sugihastuti Sugihastuti 
Published: September 2020

Tulisan ini berlatar belakang sebagai berikut. Satu hal yang patut menjadi perhatian penulis dan proses penerbitan karya ilmiah adalah edit, yaitu memperbaiki naskah atau menyunting naskah. Kata kerja edit menjadi hal yang penting dalam proses pengeditan sebelum penulis menerbitkannya. Editor, dengan demikian, menjadi orang yang penting juga dalam mengedit naskah tulisan atau karangan yang akan diterbitkan. Orang dapat menyebutnya sebagai pengedit atau penyuting. Dalam hal yang lebih spesifik, editor bahasa diperlukan dalam penyuntingan naskah. Editor bahasa bekerja untuk menyunting naskah yang akan diterbitkan dengan memperhatikan ejaan, diksi, dan struktur kalimat. Tidak hanya dalam hal itu, berbagai hal tentang penyuntingan naskah dilakukan oleh penyunting naskah, termasuk editor bahasa; lalu bagaimanakah perihal penyuntingan naskah (copyediting)?
Masalah yang muncul dalam tulisan ini, antara lain, adalah perihal copyediting. Bagaimana copyediting dapat dilakukan dengan efektif dan efisien?
Berdasar pada teori kebahasaan beserta kaidah-kaidah teknik penulisan ilmiah, metode tulisan ini merupakan metode deskriptif-kualitatif tentang copyediting. Ada (a) aspek-aspek yang diedit, (b) proses pengeditan yang cerdas, (c) prinsip kerja pengeditan, (d) peralatan pengeditan, (e) dan peringatan untuk editor bahasa.
Hasil akhir tulisan ini merupakan masukan bagi penulis karya ilmiah. Masukan-masukan itu, antara lain, berupa hal-hal yang berkaitan dengan teks-naskah, format naskah, jenis pengeditan, gaya selingkung, dan detail administrasi.
Eufemisme Dalam Rubrik Konsultasi Psikologi Psyline.Id
Authors: Febriana Dhaulika 
Published: September 2020

Pengujaran secara langsung dan literal dapat menimbulkan ketersinggungan hati akibat adanya penggunaan isitilah-istilah yang dinggap kasar, sehingga eufemisme digunakan untuk mengganti istilah yang dianggap kasar menjadi istilah yang lebih halus dan dapat diterima dengan baik guna mengurangi dampak negatif yang bisa ditimbulkan. Penelitian ini membahas tentang satuan ekspresi eufemisme yang terdapat dalam rubrik konsultasi psikologi PsyLine.id. Tujuan dari penelitian ini adalah untuk (1) mendeskripsikan bentuk dari eufemisme yang ada dalam rubrik konsultasi PsyLine.id, (2) menjelaskan jenis-jenis dari eufemisme yang ada dalam rubrik konsultasi PsyLine.id. Penelitian ini merupakan penelitian deskriptif kualitatif. Objek penelitian ini yaitu semua ujaran atau kalimat yang mengandung makna eufemisme yang terdapat dalam rubrik konsultasi psikologi PsyLine.id. Teknik pengumpulan data dalam penelitian ini menggunakan teknik dasar simak dan teknik lanjutan simak bebas libat cakap (SBLC) dan teknik catat.
Hasil dari penelitian ini yaitu (1) bentuk satuan ekspresi eufemisme dalam rubrik konsultasi psikologi PsyLine.id. berupa kata, frasa dan kalimat. Eufemisme yang ditemukan pada tataran kata berupa kata sederhana, kata kompleks, kata majemuk dan kata singkatan, (2) jenis satuan ekspresi eufemisme yang terdapat dalam rubrik konsultasi psikologi PsyLine.id. adalah figurative expressions atau ekspresi figuratif, circumlocutions atau sirkumlokusi, acronyms atau akronim, general-for-specific atau bentuk umum untuk khusus, understatements atau pengecilan permasalahan, learned terms or technical jargons atau pemakaian istilah teknis, dan borrowing atau pemakaian istilah pinjaman dari bahasa lain.
Transformasi Nama Diri Masyarakat Aceh
Authors: Fajry Khairul 
Published: September 2020

Penelitian dengan paradigma sosiolinguistik ini berfokus pada transformasi penamaan diri masyarakat Aceh yang dipengaruhi oleh unsur-unsur bahasa asing di era globalisasi. Ada banyak pendapat tentang globalisasi dan pengaruhnya terhadap budaya lokal termasuk dalam penamaan diri yang mengikuti tren westernization atau kebarat-baratan. Sebelumnya, nama Arab atau Quranic words telah melekat sejak agama islam datang ke nusantara dan telah menjadi penanda identitas bagi masyarakat muslim Aceh. Unsur bahasa asing yang dimaksud dalam penelitian ini adalah bahasa Inggris dan bahasa-bahasa yang ada di benua Eropa. Penelitian ini mengambil 100 sampel data, data dianalisis menggunakan teknik pilah unsur penanda untuk menemukan unsur bahasa asing berupa fonem dan morfem. Hasil analisis kemudian disajikan dalam bentuk tabel dan penjelasan berupa deskripsi unsur bahasa. Dari hasil penelitian ditemukan sejumlah ortografi nama diri dengan unsur bahasa asing berupa penggunaan bentuk kata asing secara utuh, modifikasi nama diri dengan unsur bahasa asing, dan transliterasi nama Arab ke dalam bahasa Inggris dan bahasa-bahasa asing lainnya. Selain itu, ditemukan pula nama-nama diri dengan unsur nama-nama tokoh muslim dan nama-nama tempat asing yang dikenal di dunia barat. Faktor pendukung transformasi nama diri pada masyarakat Aceh di antaranya disebabkan oleh pengaruh keadaan politik, perkembangan teknologi dan pengaruh budaya serta nama-nama yang berkaitan dengan peristiwa bersejarah tertentu. Di samping itu, terdapat perubahan sikap bahasa atau language attitute terhadap penggunaan unsur bahasa asing serta adanya stereotipe bahwa bahasa asing memiliki nilai yang lebih prestise dan futuristik dengan perkembangan zaman.
Anteroposterior skeletofacial classification and its relationship to maxillary second molar buccopalatal angulation
Authors: Levine Timothy P. , Matthews Gregory J. , Salama Lydia A. , Yee Alan 
Published: September 2020

ABSTRACT

Objective
To compare second molar angulation to the occlusal plane with cephalometric measurements corresponding to AP skeletal discrepancy.

Materials and Methods
72 patients' pre-orthodontic records were analyzed. A plane was constructed along the cusps of the upper second molar and measured to a proxy for the occlusal plane. The angle between the planes was measured. ANB, Wits appraisal, U1-SN, IMPA, A-B perpendicular to Frankfort, and overjet were measured on the patients' cephalograms. Generalized additive mixed model analysis was performed to analyze the relationship between the second molar angulation and the cephalometric measurements.

Results
All six cephalometric measurements showed a significant relationship with the second molar angulation, with Class III patients having a larger angle than Class II and I patients.

Conclusions
Class III patients have upper second molars that are significantly tipped from the occlusal plane. The second molars require special attention for correction prior to orthognathic surgery for Class III patients in order to avoid deleterious effects from the malpositioned teeth.
Injury hospitalizations in Canada 2018/19
Authors: Yao Xiaoquan , Skinner Robin , McFaull Steven , Thompson Wendy 
Published: September 2020

Abstract

National injury hospitalization statistics are essential for understanding the burden and pattern of injuries. This paper used the Discharge Abstract Database to analyse injury hospitalizations in Canada (excluding Quebec) for fiscal year 2018/19. The results show that unintentional injuries were the eighth leading cause of hospitalization compared to all other diseases and conditions. For unintentional injury-related hospitalizations, in rank order, the leading causes were falls, suffocation, motor vehicle traffic crashes, poisonings, struck by/against, and fire/hot object/smoke. However, the rankings were different across age groups.
AVALIAÇÃO DA PRODUÇÃO DE FORRAGEIRAS EM ÁREA DE SEQUEIRO APÓS O CONSÓRCIO DE MILHO COM E SEM INOCULAÇÃO COM Azospirillum brasilense
Authors: RODRIGUES Letí­cia Nayara Fuzaro , NAKAO Allan Hisashi 
Published: September 2020

A constante utilização do solo na região do cerrado voltado, principalmente, à produção agropecuária, trouxe, na atualidade, problemas relacionados à degradação e, como conseqüência, uma baixa produtividade das culturas. O trabalho objetivou avaliar os componentes de produtividade da matéria seca dos capins para a simulação de pastejo. O trabalho foi desenvolvido na estação experimental do NEPE, pertencente ao Centro Universitário – UNIFUNEC, localizado no município de Santa Fé do Sul-SP. O delineamento adotado foi o inteiramente casualizado, em esquema fatorial 4 x 2, com quatro repetições, constituído por quatro variedades de forrageiras como Urochloa brizantha cv. Marandu, Urochloa brizantha cv. MG-13 Braúna, Megathyrsus maximum cv. Mombaça e Megathyrsus maximum cv. Tanzânia, com e sem inoculação de Azospirillum brasilense. A cada dois meses, foram coletadas amostras dos capins para a determinação da produtividade da matéria seca. Os dados foram submetidos à ANOVA pelo teste de F, com médias comparadas pelo teste de Tukey a 5% de probabilidade. A associação das bactérias diazotróficas com as raízes das forrageiras proporcionaram desempenhos significativos na massa fresca e seca dos cultivares, mesmo em períodos de baixa disponibilidade hídrica. O uso de Azospirillum brasilense proporciona incrementos na parte aérea das espécies forrageiras, mostrando ótimos resultados.

A REVIEW OF FORAGE GRASS PRODUCTION IN DRY AREAS AFTER CORN CONSORTIUM WITH AND WITHOUT INOCULATION OF Azospirillum brasile

ABSTRACT
The constant use of soil in the cerrado region, directed mostly for farming, has currently brought some problems related to degradation, and consequently, low productivity of the cultivations. The paper aims to review the grass dry matter productivity components for simulated grazing. This paper was carried out at the research station NEPE that is part of UNIFUNEC University Center based in the municipality of Santa Fé do Sul-SP. The design used was entirely randomized, factorial scheme 4x2, 4 repetitions, consisting of a variety of 4 forages such as Urochloa brizantha cv. Marandu grass, Urochloa brizantha cv. MG-13 Braúna, Megathyrsus maximum cv. Mombaça guinea grass and Megathyrsus maximum cv. Tanzania, with and without inoculation of Azospirillum brasilense. Grass samples were collected every two months to determine the productivity of the dry matter. Data were submitted to ANOVA by statistical F test, rates were compared by using Tukey’s range test 5% of probability. The association of diazotrophic bacteria and forage roots provided a significant performance on fresh and dry matter on the cultivations, even in periods of low water availability. The use of Azospirillum brasilense provided an increase in aerial parts from forage species, presenting great results.

Keywords: Forage grass. Inoculation. Productivity.
LA MÍSTICA DEL CUSANO:
Authors: Schmitt Alexia 
Published: September 2020

Al buscar conocer el mundo y a sí mismo el hombre busca en última instancia aproximarse al principio: tal es la dimensión mística del conocer humano en Nicolás. Se advertirán tres grandes coincidencias entre la mística del Cusano y el pensamiento de San Agustín. Primera, que previo al momento místico es necesario prepararse conociendo aquello que se busca amar. Segunda: durante el momento cognoscitivo los dos advierten sobre todo la infinitud divina, y por ende, concluyen su incomprehensibilidad respecto a nuestro conocer, culminando en una docta ignorancia. No obstante, al profundizar en el significado de ïncomprehensibilidad divina y “docta ignorancia” en cada uno de estos pensadores, veremos que adquieren alcances diferentes. Tercera: sin amor no se alcanza la posesión perfecta ni la asimilación al ejemplar. En suma, para ambos, tanto el conocimiento como el amor son necesarios para arribar a la verdadera unión con Dios. Ahora bien, tal posición implica a la vez una particular concepción de mens humana, unidad de intelligere y diligere.
“To Recognize and Read Something as a Document...”: (The Transfer of Things in Research Reflections by G.L. Dain)
Authors: Andreeva Irina V. 
Published: September 2020

This article examines the cultural aspects of museum documentation as a process of identifying items to be preserved and actualized as historical documents. In the system of concepts of museum technology, it is designated as a selection process, from the point of view of museum philosophy — as implementation of the specific/museum’s attitude to reality. In the categories of cultural studies, the documentation can be considered as a subject-contextual transfer of things. This case’s formation can be now traced in the articles by J. Dolák, A.N. Balash, A.A. Nikonova, E.V. Abroskina.Basing on the analysis of published materials of the art historian G.L. Dain’s expedition diaries, the article considers the path of a thing to a museum. In addition to institutional factors, the range of her research setting includes the scientific credo of a scientist with a pronounced cultural discourse. This is “the study of toys in living connections with folk life and art, as part of the entire complex of children’s culture”, the knowledge of “the spiritual side of the mechanism of succession in folk culture”. On its basis, a corpus of individual field work methods is formed, relevant to the logic of the modern interpretive turn in the cultural sciences. Their initial message is the perception of a thing as a textual model of national culture, the setting on its multi-layer readability based on the idea of culture as a text. The article considers the subject-contextual transfer of things on the examples of acquiring the items of Bashkir, Chukchi, Eskimo and Buryat traditional cultures for museum collections. Special attention is paid to recreating things from memory by the bearers of the tradition. As a result, a conclusion is made about the five-component structure of the museum documentation process, which includes: cultural metareality — thing — document — object of museum value — museum object. The logic of transformations of things is concretized by the scheme of systematic cultural analysis: document — text — context — discourse — interpretation.
THE EFFECT OF MIXING ON THE PRODUCTION OF BIODIESEL FROM NEEM SEED OIL USING METHANOL AND HOMOGENEOUS CATALYST
Authors: Sini F. , Atadashi I. M 
Published: September 2020

Biodiesel was prepared through alkali-catalysed transesterification of neem seed oil using sodium hydroxide as catalyst and ethanol. This process of was carried out firstly throuch eserification and then via transesterification. The process was carried out by varying stirring speed (350, 450, 550, 650, 750 and 850 rpm.) and keeping other variables constant (temperature of 60oC, catalyst concentration of 1w/w% and 6:1 oil to ethanol molar ratio). In this research work, a yield of 93w/w% was achieved at the stirring speed of 850 rpm. It was observed that the viscosity (3.73mm2/s at 400C) of neem oil methylester generated was within the limit (2-6mm2/s) specified by the American Society for Testing and Materials Standards. The density of neem biodiesel at ambient temperature (250C) was found to be 0.85g/ml, which is exactly close to the density of diesel (0.83g/ml). The Flash Point of the neem oil biodiesel produced was 153.60C which above the ASTM D6751 minimum standards for biodiesel fuel of 130oC. Furthermore, Neem oil biodiesel has a pour point of -40C and a cloud point of 20C. These values clearly indicate that the use of neem oil methyl esters in colder regions is limited. However, this value is also indicative of the high potential of this fuel as biodiesel particularly in Northern Nigeria where temperature is always above 20oC, a temperature at which the oil is fluid.