bluuebunny/crossref_metadata_2025_split huggingface dataset:
Halal as a Distinct Competitive Edge for Islamic Higher Education in the Millennial Generation
Authors: Salman Abdul Matin bin , Rohman Nur , Halim Abd. , Susilayati Muslimah 
Published: April 2020

Increasing demand for halal products worldwide is one of the most prominent indicators of rising awareness of the Islamic halal concept. Thanks to increasing awareness of the benefits of halal, the concept has become a global trend in the Millennium era. Muslims are required to master the foundations of the concept of halal from the al-Qur’an and hadith, as well as its implementation in Maqasid Shariah and sciences. Mastery of halal concepts by the millennial generation can improve the competitiveness of the nation. Therefore, Islamic higher education can be seen as a significant platform for increasing halal knowledge and awareness in the millennium generation. Halal trends knowledge can provide a competitive edge in preparing the millennial generation for the increasing demands of the halal market. Purpose - This study aims to determine the implementation of halal as a distinct competitive advantage in Islamic higher education in preparing the millennial generation at The State Islamic Institute of Surakarta, Indonesia. Design/methodology/approach - The research used quantitative and qualitative methods (mixed method). Quantitative data was collected by giving out questionnaires to final semester students. Qualitative data was obtained from interviews with campus program planners. Data was analyzed with descriptive statistics before being interpreted. Findings - The results showed that 72.9% of students had studied the halal concept, 83.3% of students were able to identify halal products from MUI labels, and 45.8% understood the concepts of the Maqasid Shariah. Institutional development in halal understanding and awareness is ongoing through establishment of the halal study center and halal research center in collaboration with various parties.
Direct Anterior Approach Total Hip Arthroplasty Revisited
Authors: Flevas Dimitrios A. , Tsantes Andreas G. , Mavrogenis Andreas F. 
Published: April 2020

» In total hip arthroplasty, the advantages of the direct anterior approach (DAA) compared with the direct lateral and posterior approaches include a true intermuscular approach that spares the abductor musculature, protects the soft tissues surrounding the hip, and thus maintains hip joint stability.» The disadvantages of the DAA compared with the direct lateral and posterior approaches include a steep learning curve; intraoperative radiation exposure; injury to the nerves, vessels, and muscles; and intraoperative and early postoperative complications including blood loss, wound-healing problems, increased time under anesthesia, proximal femoral fractures and dislocations, complex femoral exposure and bone preparation, and sagittal malalignment of the stem leading to loosening and an increased revision rate.» Stem implantation in flexed sagittal position and early femoral-stem failures are more common with the DAA compared with the direct lateral and posterior approaches.
Advances in Techniques and Technology in Minimally Invasive Lumbar Interbody Spinal Fusion
Authors: Jain Deeptee , Ray Wilson Z. , Vaccaro Alexander R. 
Published: April 2020

» Minimally invasive lumbar interbody fusion has had a surge in popularity in the last decade.» Minimally invasive surgery (MIS) techniques reduce muscle dissection and soft-tissue disruption, offering faster recovery, reduced blood loss, and shorter hospital stays compared with open techniques. There is, however, a substantial learning curve associated with MIS techniques.» MIS approaches to the lumbar spine involve anterior, posterior, and combined options. This article reviews patient selection, techniques, outcomes, and complications of the common MIS approaches, including the MIS posterior approach (a transforaminal lumbar interbody fusion) and 3 MIS anterior approaches (a mini-open anterior lumbar interbody fusion, a lateral lumbar interbody fusion, and an oblique lumbar interbody fusion).
Fractures of the Cuboid Bone
Authors: Engelmann Esmee W.M. , Rammelt Stefan , Schepers Tim 
Published: April 2020

» Cuboid fractures rarely occur in isolation, and a high index of suspicion for the presence of Chopart, Lisfranc, or complex midfoot injuries should be raised.» The cuboid is the cornerstone of the lateral column and acts as a bridge between the lateral column and the transverse plantar arch. Its most important role is maintenance of lateral column length and associated motion in the midtarsal and tarsometatarsal joints.» To date, a classification system that is validated for clinical practice (i.e., guidance for management and prediction of outcome and prognosis) is lacking.» The principles of operative treatment are restoration of articular congruity, lateral column length, and stability of the Chopart and Lisfranc joints.» Nonoperative management is reserved for nondisplaced articular fractures (<1 mm) or avulsion fractures that are caused by low-energy trauma.
Team Approach: Complex Regional Pain Syndrome in Children and Adolescents
Authors: Tileston Kali R. , Griffin Anya , Wagner Jenny F.M. , O’Day Meaghan N. , Krane Elliot J. 
Published: April 2020

» Children and adolescents with chronic pain are best managed by an interdisciplinary team.» In cases of complex regional pain syndrome (CRPS), the interdisciplinary team consists of a pain management specialist, such as an anesthesiologist or physiatrist, a physical therapist, an occupational therapist, a pain psychologist, and an orthopaedist. It may also include other professions, such as a gastroenterologist, psychiatrist, nurse practitioner, nutritionist, endocrinologist, acupuncturist, or social worker.» Key factors include rapid recognition of CRPS and the initiation of appropriate treatment, both for the pain syndrome as well as for the orthopaedic injury.» Intensive therapies have been shown to be effective in treating CRPS in children. Children often are more responsive to noninvasive treatments than adults.
Diagnosis and Management of Common Hand Infections
Authors: Bilolikar Vivek K. , Seigerman Daniel A. , Ilyas Asif M. 
Published: April 2020

» While many hand infections are superficial, diligent evaluation, diagnosis, and treatment of these infections are central for preventing disability and morbidity.» Maintaining a wide differential diagnosis is important as some hand infections may mimic others.» In geographic areas with more than a 10% to 15% prevalence of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) hand infections, empiric antibiotics should adequately cover MRSA.» Once culture results are available, antibiotic regimens should be narrowed to reduce the development of resistant pathogens.
Effects of Discharge Current and Target Thickness in Dc-Magnetron Sputtering on Grain Size of Copper Deposited Samples
Authors: Et al. Yahya 
Published: April 2020

A study of the effects of the discharge (sputtering) currents (60-75 mA) and the thickness of copper target (0.037, 0.055 and 0.085 mm) on the prepared samples was performed. These samples were deposited with pure copper on a glass substrate using dc magnetron sputtering with a magnetic flux density of 150 gauss at the center. The effects of these two parameters were studied on the height, diameter, and size of the deposition copper grains as well as the roughness of surface samples using atomic force microscopy (AFM).The results of this study showed that it is possible to control the specifications of copper grains by changing the discharge currents and the thickness of the target material. The increase in discharge current values ​​led to a decrease in height copper grain's values ​​of 20% at a current of 75 mA and target thickness of 0.085 mm. Furthermore, the increasing in the current caused a decrease in the diameter and size values of deposition copper grains. Finally, the surface roughness of the samples was reduced by a 15% by changing the current and target material thickness at 75 mA and 0.085mm respectively.
Hepatoprotective Effects of Resveratrol in Non-Alcoholic Fatty Live Disease
Authors: Tejada Silvia , Capó Xavier , Mascaró Catalina Mª , Monserrat-Mesquida Margalida , Quetglas-Llabrés Mª Magdalena , Pons Antoni , Tur Josep A. , Sureda Antoni 
Published: April 2020

Background:
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic
liver disease worldwide, directly related to the progressive increase in body weight and obesity. The accumulation
of lipids in patients with NAFLD contributes to the development of insulin resistance, inflammatory response and
oxidative stress in hepatocytes and alteration of the circulating lipid and glycaemic profile. However, to date,
there are no effective pharmacological treatments for patients with NAFLD. Lifestyle changes and dietary modifications
aimed at weight loss are the best current alternatives; therefore, new approaches should be considered.
Resveratrol, a natural polyphenol of the stilbene group, is a potential candidate for the management of NAFLD
for its anti-inflammatory, antioxidant properties, and calorie restriction-like effects.

Methods:
In this review, the available information on the potential therapeutic effects of resveratrol on NAFLD,
found mainly in animal models and in some clinical trials, is summarizes.

Results:
In vitro and animal model studies have shown beneficial effects of resveratrol treatment on NAFLD.
Resveratrol reduces the hepatic accumulation of lipids and improves lipid and glycaemic metabolism. Some of
the mechanisms of action are the signalling pathways of AMP-activated protein kinase, sirtuin 1 and nuclear
factor κB. However, the results obtained in clinical trials are inconclusive.

Conclusion:
Although preclinical trials have shown promising results of resveratrol against NALFD, the lack of
clear results in clinical trials makes it necessary to conduct more studies with a larger number of patients and for a
longer time.
The Long-Term Effect of Medically Enhancing Melanin Intrinsic Bioenergetics Capacity in Prematurity
Authors: Herrera Arturo S. , Solís Arias Paola E. , del C.A. Esparza María , Bernal Luis F.T. , Bondarev Andrey D. , Fisenko Vladimir P. , Chubarev Vladimir N. , Minyaeva Nina N. , Mikhaleva Liudmila M. , Tarasov Vadim V. , Somasundaram Siva G. , Kirkland Cecil E. , Aliev Gjumrakch 
Published: April 2020

Background:
The ability of the human body to produce metabolic energy from light modifies
fundamental concepts of biochemistry.

Objective:
This review discusses the relationships between the long-accepted concept is that glucose
has a unique dual role as an energy source and as the main source of carbon chains that are precursors
of all organic matter. The capability of melanin to produce energy challenges this premise.

Methods:
The prevalent biochemical concept, therefore, needs to be adjusted to incorporate a newly
discovered state of Nature based on melanin’s ability to dissociate water to produce energy and to reform
water from molecular hydrogen and oxygen.

Results and Discussion:
Our findings regarding the potential implication of QIAPI-1 as a melanin
precursor that has bioenergetics capabilities.

Conclusion:
Specifically, we reported its promising application as a means for treating retinopathy of
prematurity (ROP). The instant report focuses on the long-term treatment medical effects of melanin in
treating ROP.
(+)- and (-)-Itampolin A: First Total Synthesis, Anticancer Effect Through Inhibition of Phospho p38 Expression
Authors: Liang Jingwei , Li Xinyang , He Xin , Sun Qi , Zhang Tingjian , Meng Fanhao 
Published: April 2020

Aim and Objective:
The brominated tyrosine alkaloids which have broad biological activity are
commonly found in marine sponges of the Verongida order, However, with the discovery of itampolin A and B
from the Madagascan sponge, Iotrochota purpurea, a plurality of brominated tyrosine derivatives have been
found in the sponge Iotrochota purpurea. This study was undertaken to study antitumor activity of itampolin A
and to explore the possible mechanism.

Material and Method:

The total synthesis of itampolin A was first performed to obtain purified brominated
tyrosine alkaloid, then the cytotoxicities of itampolin A were evaluated by MTT method against H460 and
A549 cells. To explore the possible mechanism, potential target identification by latest integrated pharmacophore
matching platform of itampolin A was carried out using PharmMapper Server. Finally, expression of
phospho p38&alpha; protein was studied using the western blot analysis.

Results:

Itampolin A and enantiomer of itampolin A were obtained, the latter is a novel compound named (-)-
itampolin A, which exhibited significant anticancer activity in the biological tests. After potential target identification
by latest integrated pharmacophore matching platform of itampolin A, p38&alpha; was screened out as the
target protein. Then in the Western-blot analysis, it was proposed that (-)-itampolin A inhibited tumor cells by
reducing the phospho-p38&alpha; expression.

Conclusion:

(+)-itampolin A was a brominated tyrosine derivative, isolated from the sponge Iotrochota purpurea.
For the first time, the total synthesis of itampolin A was achieved. The enantiomer, (-)-itampolin A was
found to show inhibitory activity on the cultured lung cancer A549 cells. The underlying anticancer mechanisms
may be associated with its binding to p38&alpha; and then decrease in the phospho-p38 expression.
Stem Cell Therapies for the Treatment of Diabetic Neuropathies: Future Perspectives
Authors: de Figueiredo Camila Saggioro , dos Reis Luiz Carlos 
Published: April 2020

Background:
Background: Diabetic neuropathies (DN) are the most common complications in diabetic
patients, affecting about 70% of them. Patients with DN may lose sensation in certain areas of the body,
facilitating the onset of foot ulcers, as well as chronic pain. This is due to the progressive degeneration
of nerve fibers, demyelination, and axonopathy. Recent studies about stem cell therapies for the treatment
of DN show promising potential for tissue regeneration. Results with mesenchymal stem cells derived
from various organs/tissues demonstrate great therapeutic potential considering their easy obtainment,
as well as their immunomodulatory and pro-regenerative effects. However, problems such as cell
transplant rejection, tumor formation, transplantation safety, and effectiveness still need to be solved.
Developmental biology lacks detailed insights into some aspects of cell mechanisms, like the genetic
components of cell growth or differentiation. These gaps can limit a rapid advance in stem cell therapy
research and put it in the future a little bit farther from the expectations that have emerged in recent media.

Conclusion:
In the present review, we attempt to discuss the potential of most studied types of stem
cells, their application for the treatment of experimental diabetic neuropathies and associated clinical
manifestations including future perspectives around these themes.
FRAMING DAN GENDER DALAM KEPATUHAN PAJAK : STUDI EKSPERIMEN
Authors: Prastiwi Titisari Dian , Damayanti Theresia Woro 
Published: April 2020

Framing causes differences individual behavior in making various decisions. One of them is the decision regarding tax compliance. This research study’s aimed to examine where there are differences in tax compliance behaviour between those who receive positive and negative framing and differences in individual tax compliance behavior based on personal attributes in the form of masculine and feminine gender. Prospect theory used as a basis for explaining changes in individual behavior when receiving framing effects. This study was conducted by primary data in the scope of Bachelor’s Degree of Accountancy at FEB UKSW who took Taxation Management. This experiment design was consisted of 2 x 2 between subject factorial designs. The result of this study prove that there is no influence between framing and gender on tax compliance.The results that obtained from the examination of interaction also prove that there is no influence that is difference between positive and negative framing and or masculine and feminine gender on tax compliance.
Respon terhadap Otentisitas: Tanggapan Wisatawan Asing terhadap Unsur-unsur Budaya dalam Tiga Hotel Internasional di Bali
Authors: Prasista Bestari I Putu , Suryawardani I. G.A. Oka , Suryawan Wiranatha Agung 
Published: April 2020

Artikel ini meneliti bagaimana wisatawan mancanegara menanggapi elemen budaya Bali yang otentik yang ditampil-kan oleh pelaku bisnis perhotelan di Bali, dengan mengambil tiga hotel internasional sebagai objek studi, yaitu Nusa Dua Beach Resort dan Spa Hotel, W Hotel Seminyak, dan Four Seasons Resort di Ubud. Tiga hotel ini dipilih karena merupakan hotel internasional dan terletak di tiga tujuan wisata yang berbeda, tetapi semuanya menawarkan elemen budaya Bali dalam pelayanannya. Masalah yang dibahas adalah bagaimana tanggapan wisatawan terhadap unsur-unsur budaya Bali, terutama tentang arsitektur, makanan, seni budaya, dan pelayanan. Penelitian ini bersifat kualitatif, data diambil dengan teknik netnografi dalam bentuk komentar wisatawan tentang pelayanan di hteo tempatnya menginap yang diposting di web Tripadvisor. Data dianalisis dengan teori respons dan teori analisis konten interpretif. Analisis menunjukkan bahwa tertarik terhadap unsur-unsur budaya Bali yang otentik. Disaran agar hotel-hotel internasional menampilkan elemen budaya Bali secara eksplisit untuk mendukung citra Bali sebagai destinasi wisata budaya.Kata kunci: budaya Bali, arsitektur, makanan Bali, netnografi, hospitaliti
Incidence of Major Vascular Injuries with Extreme Lateral Interbody Fusion (XLIF)
Authors: Epstein Nancy E 
Published: April 2020

Background:
Extreme lateral interbody fusions (XLIF) and minimally invasive (MI) XLIF theoretically offer wide access to the lumbar disc space. The theoretical advantages of XLIF include; minimally disturbing surrounding structures (e.g. neural, vascular, soft-tissue), while offering stability. In addition to the well-known increased frequency of neurological deficits attributed to XLIF, here we explored how often major vascular injures occur with XLIF/MI XLIF procedures.

Methods:
In 13 XLIF/MI XLIF studies, we evaluated the frequency of major vascular injuries.

Results:
The studies citing the different frequencies of vascular injuries associated with XLIF/MI XLIF were broken down into three categories. Of the 5 small and larger case series, involving a total of 6,732 patients (e.g. range of 12 to 4,607 patients/study), the incidence of vascular injuries ranged from 0% (3 studies) up to 0.4%. Three case reports presented major vascular injuries attributed to XLIF/MI XLIF. Two involved the L4-L5 level. The three complications included: one fatal injury, one, a retroperitoneal hematoma with hemorrhagic shock, and one major vascular injury. For the 5 review articles, major vascular complications were just discussed in 2, one study cited 3 specific major vascular injuries (e.g. 1 fatal, 1 life threating, and 1 lumbar artery pseudoaneurysm requiring embolization), while 2 other studies stated the frequency of these injuries was 0.4% for XLIF, and 1.7 % for OLIF (Oblique Lumbar Interbody Fusion).

Conclusions:
According to 5 small and larger case series, 3 case reports, and 5 review articles, the incidence of major vascular injuries occurring during XLIF/MI XLIF ranges from 0 to 0.03% to 0.4%.
Colloquiality analysis on social networks
Authors: França Batista Andre Luiz , Da Silveira Campos Carlos Henrique , Ramos Pimentel Daniel 
Published: April 2020

Social network sites are present in a constant way in society. The manner people write in social network sites has their dynamism because of the speed information are replicated, the reach publications may have, network sites’ peculiarities and the seek for fame. This generates linguistic constructions that are not in accord with the standard norm of the Portuguese language. This quantitative work aims to relate the use of colloquial constructions on Twitter with user's popularity, posts popularity and other specific factors of this social network. This analysis was made using regular expressions, dictionaries, and frequency distribution to identify colloquial constructions. A support system was developed to perform analysis, management, and mining.
Symbolism of title in Goran's poem
Authors: Abdulla Abas Salih 
Published: April 2020

لەئەمڕۆدا ڕەخنەی كلاسیكی، بۆتە بنەماو بنچینەیەكی گرنگی رەخنەودیاریكردنی بنەماكانی رەخنەگرتن، ئەمەش لە سۆنگەی بۆچوونەكانی ئەرستۆڤانس وسۆكرات و ئەفلاتون و ئەرستۆوە سەرچاوەی گرتووەو بۆچونەكانیان بوونەتە بنەمایەكی زانستی بۆدیاریكردنی بنەماكانی شیعر و پێوانە ڕەخنەییەكان، لەم لێكۆڵینەوەیەدا هەوڵدراوە ئەو پێوانە رەخنەیانە دیاریبكرێت، كە لەئەدەبی یۆنانی و رۆمانیدا هەیە، تاوەكو پێوانەكانیان ببنە بنەمایەكی سەرەكی كاركردن لەدەقە ئەدەبییەكاندا، لێرەوە رەوتێكی رەٍخنەی بەهێز بۆدەقی ئەدەبی بونیاد دەنرێت .
جگەلەمەش ئەم پێوانە و پێوەرانە لەلایەك هۆكاری هەڵسەنگاندنن، لەلایەكی تریشەوە پێوانەی بریاردانن ، بۆیە چارەنووس و لاساییكردنەوەی دەق لەڕێگەی ئەم پێوانانەوە دەبێت.
The Symbolic Significance of the ‘Ring-Plot’ in Shakespeare’s The Merchant of Venice.
Authors: Rasheed Shirin Saadullah , Omar Kawa Osman 
Published: April 2020

ئەم توێژینەوە یە هەوڵ ئەدات بەشێکی گرنگ لە تەکنیکی گرێی درامی لە کۆمیدیای ڕۆمانسی ویلیەم شەکسپیر ( بازرگانی ڤینیسیا ) بخاتە ژێر شیکاری ئەدەبی. ئەوەی جێی سەرنجە پەیوەندیەکی پتەوی بابەتی و بونیادی لە نێوان چەندین گرێی درامی هەمەجۆر هەیە لە درامای شەکسپیردا، وهەر یەک لەو گرێ درامیانەش تایببەتمەندی خۆی هەیە لە دیاری کردنی ڕۆڵی پاڵەوانی ئافرەت لە کۆمیدیاکە بە تایبەتی تواناو لێهاتووی ئەو پاڵەوانە لە بەکارهێنانی ئاخاوتن و فێڵی درامی. توێژینەوەکە بەتایبەتی شیکاری ئەدەبی بۆ گرێی درامی سێیەم دەکات لە دراماکە، ئەویش بە هۆی گرنگی ئەم گرێدرامیە لە دیاری کردنی ڕۆڵی گرنگی پاڵەوانە ئافرەتەکە لە گۆڕینی ئاراستەی ڕوداوی سەرەکی دراماکە، هەروەها دەرخستنی ڕۆلی ئەو پالەوانە ئافرەتە لە گۆڕینی کەسایەتیە سەرەکیەکەی دراماکە بۆ کەسایەتیەکی پێگەیشتووی خاوەن خود ، لە هەمووی گرنگتر توێژینەوەکە شیکارێکی ئەدەبی ئەکات بۆدیاریکردنی پەیوەندیی لە نێوان تەکنیکی ئاخاوتنی تایبەت بە پاڵەوانە ئافرەتەکە و هەوڵی بەدەستهێنانی خودی خۆی لە گرێی درامی سێهەمدا.