bluuebunny/crossref_metadata_2025_split huggingface dataset:
Underdiagnosis of VT due to cycle length variation among cardiac sarcoidosis patients having ICD: Problem with stability discriminator
Authors: Bera Debabrata , Pavri Behzad B. , Saggu Daljeet Kaur , Devidutta Soumen , Yalagudri Sachin , Subramanian Muthiah , Sridevi Chennapragada , Narasimhan Calambur 
Published: April 2020

AbstractBackgroundImplantable cardioverter defibrillator (ICD) is recommended for patients with ventricular tachycardia (VT) due to cardiac sarcoidosis (CS). Programming supraventricular tachycardia (SVT) discriminators (onset, stability, and morphology/template match) is generally recommended to minimize inappropriate therapies. However, VT in patients with CS is known to show cycle length variability (CLV) and pleomorphism.ObjectiveTo determine whether the stability criterion, designed to prevent inappropriate therapy during atrial fibrillation with rapid ventricular rates, could potentially lead to incorrect classification of VT as SVT and inappropriately delay or inhibit ICD therapy.MethodsCases of biopsy‐proven CS with VT were analyzed. For patients with implanted devices, all recorded electrograms of tachycardia episodes and ICD therapies were analyzed at last follow up.ResultsA total of 142 patients were included (mean age 38 years, 87 males). One hundred and three of 142 patients had implanted devices (ICD or CRT‐D). Thirty eight of 103 (36.9%) patients received appropriate ICD therapies over 3 ± 2.2 years follow up. Four of 38 (10.5%) of patients experienced delayed‐detection or underdetection of VT related to CLV, resulting in VT counters being repeatedly “reset” (classified as “unstable” rhythms). Retrospective analysis of other VT episodes in 70 of 103 (68%) patients revealed that 25 of 80 (31.3%) episodes had > 50 ms cycle length oscillations.ConclusionAmong CS patients with VT, CLV is a common occurrence seen in two‐thirds of VT episodes. Routine programming of the stability criterion may result in underdetection of VT in a subset of such patients. We recommend that the stability criterion should be programmed “OFF” for patients with CS, unless the patient has documented atrial fibrillation.
Current tools measuring anxiety in parents of food‐allergic children are inadequate
Authors: Soller Lianne , To Sharon , Hsu Elaine , Chan Edmond S. 
Published: April 2020

AbstractBackgroundIn the context of food allergy, excessive parental anxiety can be maladaptive and lead to unnecessary restriction of social activities. No validated tool exists to measure food allergy–associated anxiety (FAAA). This study sought to explore factors associated with parental FAAA, determine sensitivity and specificity of using generic state anxiety measure—State‐Trait Anxiety Inventory (STAI) versus FAAA, and determine whether validated tools for generalized anxiety or food allergy–specific quality of life (QoL) could be used as surrogates for FAAA.MethodsCanadian parents of food‐allergic children completed an online survey. Without a validated tool for FAAA, a visual analogue scale was used to assess parent‐reported FAAA. Multivariable linear regression was performed with FAAA as the outcome. Sensitivity and specificity analysis of state anxiety vs. FAAA, and factor analysis of state anxiety and QOL, was performed to determine whether these could be used as surrogates for FAAA.ResultsA total of 548 of 1244 parents (44.1%) completed the survey. Factors positively associated with FAAA included parental burden, risk perception, state anxiety, intolerance of uncertainty and perceived severity of child's food allergy; personal/family history of mental health was negatively associated. Sensitivity and specificity of state anxiety were 68.6% and 70.0%. Factor analysis revealed that state anxiety and QOL were correlated (r = 0.54, P < .001) but distinct constructs.ConclusionOur study identified factors associated with FAAA, and determined that generic anxiety and QOL tools do not accurately categorize parents with self‐reported high FAAA. Future research will develop a validated screening tool to help allergists identify anxious parents and provide psychosocial resources.
Patient–therapist congruent exchanges engaged with the potential‐to‐experience is associated with better outcome of psychotherapy
Authors: Bar Mor , Saad Amit , Slonim‐Atzil Dana , Tuval‐Mashiach Rivka , Gour Tamir , Baron Noga , Mendlovic Shlomo 
Published: April 2020

BackgroundThe concept of potential‐to‐experience is a major component in psychodynamic theory and assumed to be an important component of psychotherapeutic technique. However, as this assumption has never been empirically tested, the relationship between such interventions and treatment outcome is unclear. The aim of this pilot study is to explore the relationship between patient–therapist congruence of potential‐to‐experience engaged statements and the outcome of psychodynamic treatments.MethodsTranscripts of 90 sessions from good‐ and poor‐outcome treatments (N = 18) were encoded using the MATRIX – a novel content analysis tool of psychodynamic psychotherapy. Based on fixed algorithms, this observer‐coding system is designed to identify different types of clinical interventions, including those which focus on the potential‐to‐experience. Total number of MATRIX codes analysed was 11,125. We compared the total congruence/incongruence ratio of such statements in good and poor treatments. The importance of the congruence/incongruence ratio of the potential‐to‐experience statements was measured by applying general linear models to classify treatment outcome.ResultsThe congruence/incongruence ratio of the potential‐to‐experience engaged statements was significantly higher in good treatments. In the best model for classifying treatment outcome based on the congruence/incongruence ratios of several parameters, the congruence/incongruence ratio of the potential‐to‐experience engaged statements was the single most important predictor.DiscussionMaintaining the congruence of potential‐to‐experience engaged statements within the therapeutic session is associated with better clinical outcome. This provides an initial empirical indication to the importance of the potential‐to‐experience discourse in psychotherapy praxis.Practitioner points

The concept of potential‐to‐experience is a major component in psychodynamic theory and assumed to be an important component of psychotherapeutic technique.

The current results suggest that the ability of both patient and therapist to maintain the congruence of potential‐to‐experience statements within the session may improve clinical outcomes.

These findings suggest a practical approach for a better management of the therapeutic process. Mainly, it recommends therapists to implement a very careful, active listening to potential‐to‐experience‐related content throughout the session, while highlighting the patient’s associations for their potential to become new modus operandi.

Moreover, the current study presents an integrative, micro‐level tool that enables the translation of complex theoretical concepts in psychotherapy into measurable constructs, aiming at the creation of a bridge between clinical theory and evidence‐based practice.
Levetiracetam‐induced pediatric toxic epidermal necrolysis successfully treated with etanercept
Authors: Estébanez Andrea , Sáez‐Martín Luis Carlos , Muñoz Juan Ignacio , Silva Esmeralda , Monrabal Alicia , Monteagudo Carlos , Ramón María Dolores 
Published: April 2020

AbstractSuccessful management of toxic epidermal necrolysis (TEN) with tumor necrosis factor‐α inhibitors has been described in adults, but few cases have been reported in children. To date, only four pediatric cases of TEN treated with infliximab and one with etanercept have been published. We present the case of an 8‐year‐old boy diagnosed with TEN induced by levetiracetam, successfully treated with etanercept, systemic corticosteroids, and intravenous immunoglobulin.
Pediatric liver transplantation from a living donor in mitochondrial disease: Good outcomes in DGUOK deficiency?
Authors: Hassan Shahzeb , Mahmoud Ali , Mohammed Taha Osman , Mohammad Saeed 
Published: April 2020

AbstractDGUOK deficiency is an autosomal recessive mitochondrial disorder characterized by hepatic and neurological manifestations. In patients with liver failure, the decision to perform LT can be difficult due to the likelihood of progressive neurological disease. We present a case of a 9‐month‐old boy who had DGUOK deficiency (E227K/R118H genotype) intact neurological status and liver failure. His MRI indicated extensive white matter changes, which created hesitation to perform LT. After a multidisciplinary evaluation, he underwent LT from a living donor at 11 months of age. Six years post‐transplant, he has had no significant complications and no progression of neurological symptoms. Our case supports that even in the presence of neurological MRI findings, but in the absence of significant neurological symptoms, LT represents a viable option in DGUOK‐deficient patients who have the E227K/R118H mutation combination along with liver failure.
Psychophysiological responses to eye contact in a live interaction and in video call
Authors: Hietanen Jonne O. , Peltola Mikko J. , Hietanen Jari K. 
Published: April 2020

AbstractAnother person's gaze directed to oneself elicits autonomic arousal and facial reactions indicating positive affect in its observer. These effects have only been found to occur with mutual, live eye contact and not in response to direct gaze pictures or when the observer believes that the live person cannot see them. The question remains whether the physical presence of the other person is necessary for these effects. We measured psychophysiological responses to another person's direct versus averted gaze in three conditions: live interaction, bidirectional video call, and watching a mere video. Autonomic arousal was measured with skin conductance responses and facial reactions with facial electromyography. In the live and video call conditions, but not in the mere video condition, direct gaze increased autonomic arousal in comparison to averted gaze. In all three conditions, however, direct gaze elicited positive affective facial reactions. Therefore, an experience of being seen is essential for the autonomic reactions but not for the facial responses that are elicited by another person's direct gaze. Most importantly, the results suggest that the physical presence or proximity of the other person is not necessary for these psychophysiological responses to eye contact.
An Optimal Design for Hierarchical Generalized Group Testing
Authors: Malinovsky Yaakov , Haber Gregory , Albert Paul S. 
Published: April 2020

SummaryChoosing an optimal strategy for hierarchical group testing is an important problem for practitioners who are interested in disease screening with limited resources. For example, when screening for infectious diseases in large populations, it is important to use algorithms that minimize the cost of potentially expensive assays. Black and co-workers described this as an intractable problem unless the number of individuals to screen is small. They proposed an approximation to an optimal strategy that is difficult to implement for large population sizes. We develop an optimal design with respect to the expected total number of tests that can be obtained by using a novel dynamic programming algorithm. We show that this algorithm is substantially more efficient than the approach that was proposed by Black and co-workers. In addition, we compare the two designs for imperfect tests. R code is provided for practitioners.
Bringing new plasma donors back: testing the efficacy of telephone and e‐mail communications with first‐time donors
Authors: Thorpe Rachel , Masser Barbara M. , Nguyen Lilly , Gemelli Carley N. , Davison Tanya E. 
Published: April 2020

BACKGROUNDAs demand for plasma‐derived products grows, retention of voluntary nonremunerated plasmapheresis donors is crucial for many blood collection agencies. Currently, there is limited evidence of how to encourage first‐time plasmapheresis donors to return and establish a high‐frequency donation routine. This study tested the effectiveness of an intervention designed to increase retention of first‐time plasmapheresis donors, increase donation frequency, and reduce time to return.STUDY DESIGN AND METHODSA total of 6788 first‐time plasmapheresis donors were randomly assigned to one of four conditions. Donors received an alternative e‐mail or the business‐as‐usual control e‐mail paired or not with a phone call. Outcomes were compared to the control e‐mail in intention‐to‐treat analyses.RESULTSCompared with control, donors in all intervention conditions were more likely to donate plasma as their first return donation in 6 months; however, there were no significant differences between intervention conditions. Rates of plasma donation in the alternative e‐mail, control e‐mail plus call, and alternative e‐mail plus call conditions were 17.0, 15.0, and 18.0% higher than control. While the extra donations obtained in the alternative e‐mail condition were cost neutral, the cost of one additional donation in the call conditions ranged from 20.14‐20.89 AUD (13.08‐13.56 USD).CONCLUSIONCommunications specifically designed to encourage first‐time plasmapheresis donors to view regular plasmapheresis donations as “easy”; to forward‐book more than one appointment; and to provide education about plasma are effective in encouraging donors to return to plasma, to donate more frequently, and to return faster.
Evaluating the influence of extending hydrologic time series in extreme quantile estimation
Authors: Jesus Lucas Filipe Lucena , Costa Veber , Fernandes Wilson 
Published: April 2020

AbstractReliable estimates of quantiles associated with mid‐to‐large return periods are required in the everyday practice of Hydrologic Engineering. However, the usually small samples pose numerous challenges for inferring such quantiles. Therefore, augmenting sample sizes via extension techniques could be beneficial for statistical inference. This paper attempts to provide a comprehensive assessment of the performance of a collection of such techniques in estimating rare and extreme quantiles. Regression models, such as the ordinary least squares (OLS) approach and the Generalised Linear Models (GLM), as well as techniques specifically designed for time series extension, such as the Maintenance of Variance (MOVE) family, were evaluated by means of Monte Carlo simulations. Results show that, for both two and three‐parameter distributional models and any level of association, the MOVE3 and MOVE4 techniques appear to provide the best balance between bias and precision of extreme quantile estimates.
Discussion: “Effect of Porous Medium in Stagnation Point Flow of Ferrofluid Due to a Variable Convected Thicked Sheet” [ASME J. Heat Transfer, 2019, 141 (11), p. 112602]
Authors: Awad M. M. 
Published: April 2020

Abstract
The current discussion is presented to increase the awareness among the readers of ASME Journal of Heat Transfer. Comments are presented on the paper by Imtiaz et al. [1], where the authors investigated the influences of porous medium and stagnation point flow on ferrofluid flow past a variable-thicked sheet. Correction for the definition of the stream function (ψ) is given. These correct relations of the stream function (ψ) satisfies the continuity equation. In addition, correction for the first boundary condition is given.
Internal Wind Pressures and Buckling Behavior of Large Cylindrical Floating-Roof Tanks Under Various Liquid Levels
Authors: Zhao Yang , Liu Qing , Cai Shuqi , Dong Shilin 
Published: April 2020

Abstract
In this paper, two practical large cylindrical floating-roof tanks with diameters of 60 m and 100 m are selected as research objects. Wind pressures on the internal wall of tank shells under various liquid levels are carefully investigated by both experimental and numerical methods, especially those around the sealing device. It is found that computational fluid dynamics (CFD) simulation gives similar but generally greater results than wind tunnel tests (WTTs), and that wind pressures around the sealing device increase with the rise of liquid level. Geometrically nonlinear analyses (GNA) are then performed to figure out the variation of buckling behavior of tank shells with the liquid level. Two buckling modes are specified, featured by large buckles in the unstiffened region and local short-wave buckles in the stiffened region, respectively. Buckling loads are found to increase stepwise with the liquid level, with critical heights roughly calculated by positions of stiffening rings. Finally, recommendations on liquid levels maintained in strong wind conditions are given, considering the safety of both sealing devices and tank shells.
Analytical Solutions for the Lateral-Torsional Buckling of Serpentine Interconnects in Stretchable Electronics
Authors: Feng Peng , Yuan Jianghong , Huang Yin , Li Xiangyu 
Published: April 2020

Abstract
Serpentine interconnects, as an integral part of island-bridge layouts, enable extremely large reversible deformation under the action of mechanical loads and are thus widely used in the emerging new field of stretchable electronics. In this paper, the lateral-torsional buckling is analytically studied for a simplified S-shaped serpentine structure that consists of five straight components rigidly connected at point joints. Simple analytic scaling laws between the dimensionless critical buckling load and the aspect ratio of the serpentine structure are newly derived and uniformly expressed in terms of generalized hypergeometric series for various types of boundary conditions, which can serve as the benchmark of numerical simulations. These scaling laws, fully verified by finite element analysis, may well capture the implied connection between stretching- and compression-induced buckling, the strong dependence of buckling modes on end conditions, and the monotonic/asymptotic properties of the critical load with respect to the aspect ratio of serpentine structures.
Numerical Study on Effect of Secondary Surface on Rectangular Vortex Generator
Authors: Kashyap Uddip , Das Koushik , Debnath Biplab Kumar , Kashyap Upasana , Saha Sandip K. 
Published: April 2020

Abstract
One way of achieving higher efficiency in electro-mechanical is by inducing vortices over the heated surface with the help of a vortex generator (VG). The strength of these vortices is proportionate to the amount of heat transported. In this paper, the evolution and propagation of the produced primary vortex behind a VG with the attached secondary surface (SS) are studied experimentally and numerically. The addition of SS is found to augment heat transfer significantly with an additional drag. The obtained experimental results complement the numerical predictions for the modified VG. Linear regression analysis is performed to optimize the geometry of SS for a higher heat extraction rate and lower drag. The SS placed at an optimum location increases the Nusselt number on the heated plate by 8.9%, with a decrement in the drag by 3.2%, compared to the reference case. The addition of SS produces a vortex of higher strength and propagates downstream at a slower rate. Moreover, it exposes the vortex to higher shear in the flow, which in turn enhances the heat transfer rate.
Trace-elemental and petrographic constraints on the severity of hydrographic restriction in the silled Midland Basin during the late Paleozoic ice age
Authors: Peng Junwen , Fu Qilong , Larson Toti E. , Janson Xavier 
Published: April 2020

AbstractEnrichment of redox-sensitive trace elements in ancient marine shales is conventionally believed to be controlled by marine benthic redox conditions, whereas the influence of hydrographic conditions on trace element enrichment pattern has been rarely considered. Here, we present newly obtained data sets from the Upper Pennsylvanian organic-rich Cline Shale in the Midland Basin, Texas, to illustrate the influence of hydrographic circulation on the trace-element enrichment pattern and the stratigraphic record of mudrocks. Various lithofacies, including siliceous mudrocks, argillaceous mudrocks, skeletal-bearing argillaceous mudrocks, calcareous mudrocks, and wackestone, are identified in the Cline Shale. Significant changes in the trace-element enrichment pattern, mineral composition, texture of framboidal pyrite, and other bulk geochemical parameters in different lithofacies are interpreted to have been caused by high-amplitude and high-frequency glacio-eustatic sea-level oscillations in the silled Midland Basin during the late Paleozoic ice age. Specifically, glacio-eustatic sea-level falls generally resulted in the severe isolation of the Midland Basin from the Panthalassic Ocean, highly restricted hydrographic circulation, long deep-water renewal time, euxinic bottom-water conditions, depleted seawater Mo (molybdenum) in the silled basin, and low sediment Mo/TOC (total organic carbon), coupled with significant extrabasinal detrital quartz input, forming siliceous mudrocks. Enhanced phosphorus cycling and excellent preservation conditions are considered to be responsible for the high TOC observed in siliceous mudrocks. In contrast, glacio-eustatic sea-level rises substantially enhanced water exchange between the basin and the Panthalassic Ocean, created overall suboxic to anoxic bottom-water conditions, resupplied seawater Mo, elevated sediment Mo/TOC, and increased platform carbonate production in the basin, forming calcareous mudrocks and wackestone.
Ontology to identify pregnant women in electronic health records: primary care sentinel network database study
Authors: Liyanage Harshana , Williams John , Byford Rachel , de Lusignan Simon 
Published: April 2020

ObjectiveTo develop an ontology to identify pregnant women from computerised medical record systems with dissimilar coding systems in a primary care sentinel network.Materials and methodsWe used a three-step approach to develop our pregnancy ontology in two different coding schemata, one hierarchical and the other polyhierarchical. We developed a coding system–independent pregnancy case identification algorithm using the Royal College of General Practitioners Research and Surveillance Centre sentinel network database which held 1.8 million patients’ data drawn from 150 primary care providers. We tested the algorithm by examining individual patient records in a 10% random sample of all women aged 29 in each year from 2004 to 2016. We did an external comparison with national pregnancy data. We used χ2test to compare results obtained for the two different coding schemata.Results243 005 women (median age 29 years at start of pregnancy) had 405 591 pregnancies from 2004 to 2016 of which 333 689 went to term. We found no significant difference between results obtained for two populations using different coding schemata. Pregnancy mean ages did not differ significantly from national data.DiscussionThis ontologically driven algorithm enables consistent analysis across data drawn from populations using different coding schemata. It could be applied to other hierarchical coding systems (eg, International Classification of Disease) or polyhierarchical systems (eg, SNOMED CT to which our health system is currently migrating).ConclusionThis ontological approach will improve our surveillance in particular of influenza vaccine exposure in pregnancy.