bluuebunny/crossref_metadata_2025_split huggingface dataset:
Closed laparoscopic and endoscopic cooperative surgery for early gastric cancer with difficulty in endoscopic submucosal dissection: a report of three cases
Authors: Saito Hiroshi , Nishimura Akihiro , Sakimura Yusuke , Tawara Hiroki , Hayashi Kengo , Kato Kaichiro , Tsuji Toshikatsu , Yamamoto Daisuke , Kitamura Hirotaka , Kadoya Shinichi , Bando Hiroyuki 
Published: September 2020

Abstract
Background
Endoscopic submucosal dissection (ESD) is increasingly applied for early gastric cancer. ESD is a less invasive procedure and could be a radical treatment. However, in some cases, ESD cannot be completed owing to patient or technical factors. In such cases, which could have the potential for curative resection with ESD, standard gastrectomy is excessively invasive. Through closed laparoscopic and endoscopic cooperative surgery (LECS), gastric tumor can be precisely resected without exposing tumor cells to the abdominal cavity. Compared with standard gastrectomy, closed LECS is less invasive for the treatment of early gastric cancer.

Case presentation
We performed closed LECS for three cases of early gastric cancer after failed ESD. In all three cases, ESD was interrupted owing to technical and patient factors, including perforation, respiratory failure, and carbon dioxide narcosis. All three cases successfully underwent closed LECS with complete tumor resection and showed an uneventful postoperative course. All three patients remain alive and have experienced no complications or recurrence, with a median follow up of 30 (14–30) months.

Conclusions
Closed LECS is less invasive and useful procedure for the treatment of early gastric cancer, particularly in cases with difficulty in ESD.
Biodiversity of butterflies in endosulfan-affected areas of Kerala, India
Authors: Raghavendra K. N. , Arvind Kumar , Anushree G. K. , Grace Tony 
Published: September 2020

Abstract
Background
Butterflies are considered as bio-indicators of a healthy and diversified ecosystem. Endosulfan was sprayed indiscriminately in large plantations of Kasaragod district, Kerala which had caused serious threats to the ecosystem. In this study, we surveyed the butterflies for their abundance and diversity in three differentially endosulfan-affected areas viz., Enmakaje—highly affected area, Periye—moderately affected area, Padanakkad—unaffected area, carried out between the end of the monsoon season and the start of the winter season, lasting approximately 100 days. Seven variables viz., butterfly abundance (N), species richness (S), Simpson’s reciprocal index (D), the Shannon–Wiener index (H′), the exponential of the Shannon–Wiener index (expH′), Pielou’s evenness (J) and species evenness (D/S), related to species diversity were estimated, followed by the one-way ANOVA (F = 25.01, p < 0.001) and the Kruskal-Wallis test (H = 22.59, p < 0.001).

Results
A population of three different butterfly assemblages comprised of 2300 butterflies which represented 61 species were encountered. Our results showed that Enmakaje displayed significantly lower butterfly diversity and abundance, compared to the other two communities.

Conclusion
So far, this is the first study concerning the effect of endosulfan on the biodiversity of butterfly in the affected areas of Kasaragod, Kerala, India. This study may present an indirect assessment of the persisting effects of endosulfan in the affected areas, suggesting its long-term effects on the ecosystem.
Concurrent breast adenoid cystic carcinoma and primary squamous cell carcinoma: report of a rare case with single institutional case reviews
Authors: Yan Mingfei , Bomeisl Phillip , Gilmore Hannah , Harbhajanka Aparna 
Published: September 2020

Abstract
Background
Adenoid cystic carcinoma and primary squamous cell carcinoma are both rare breast neoplasms, which possess drastically different morphological and molecular features as well as distinguishing clinical behaviors and prognosis.

Case presentation
In this report, we described a rare case in which concurrent adenoid cystic carcinoma and keratinizing squamous cell carcinoma were diagnosed in contralateral breasts in an 85 year-old female patient. The patient had a history of adenoid cystic carcinoma diagnosed 11 years ago, which was treated by partial mastectomy followed by whole breast radiation. The recurrent carcinoma on the same side of the breast was small in size but appeared to involve an intraductal papilloma. Also, a newly occurred large cystic mass was identified on the contralateral breast, which histologically presented as a keratinizing squamous cell carcinoma with no glandular differentiation. No in situ or invasive carcinoma was identified in the overlying skin of the lesion, and no malignancy in a second site was found by PET-CT. Therefore, this lesion was mostly likely a primary squamous cell carcinoma of the breast.

Conclusion
The concurrence of two such rare neoplasms was likely an incidental finding or was therapy-related. However, more mechanistic studies are needed in order to understand whether predisposing genetic alterations exist in this rare case. Besides, cases of both breast adenoid cystic carcinoma and carcinoma with predominant squamous differentiation diagnosed in our institution were reviewed, which help to better characterize their clinicopathological features.
Ruptured pancreaticoduodenal pseudoaneurysm causing arterioportal fistula: combined transarterial and transportal embolization
Authors: Waguri Nobuo , Azumi Rie , Osaki Akihiko , Sato Munehiro , Aiba Tsuneo , Furukawa Koichi 
Published: September 2020

Abstract
Background
Arterioportal fistulas are rare vascular disorders of the abdominal viscera. They are arteriovenous communications between the splanchnic arteries and the portal vein or its tributaries. We herein report a case of an extrahepatic arterioportal fistula that was caused by rupture of a pseudoaneurysm of the pancreaticoduodenal artery and successfully treated with embolization using a combination of the arterial and percutaneous transhepatic portal venous approaches.

Case presentation
A 79-year-old man was transferred to our hospital because of the sudden appearance of a hematoma containing a large pseudoaneurysm in the mesentery of the duodenum. Emergency abdominal angiography revealed that a pseudoaneurysm of the anterior inferior pancreaticoduodenal arterial branch had perforated into the portal system (arterioportal fistula). We performed coil embolization via the inflow artery and portal vein using a percutaneous transhepatic approach. The patient recovered without complications and was discharged.

Conclusion
This rare vascular disorder was successfully treated with an unplanned combination therapy. We believe that flexible strategy changes led to the successful treatment in this case.
Microbial co-occurrence networks of gut microbiota reveal community conservation and diet-associated shifts in cichlid fishes
Authors: Riera Joan Lluís , Baldo Laura 
Published: September 2020

Abstract
Background
The extent to which deterministic rather than stochastic processes guide gut bacteria co-existence and ultimately their assembling into a community remains largely unknown. Co-occurrence networks of bacterial associations offer a powerful approach to begin exploring gut microbial community structure, maintenance and dynamics, beyond compositional aspects alone. Here we used an iconic model system, the cichlid fishes, with their multiple lake assemblages and extraordinary ecological diversity, to investigate a) patterns of microbial associations that were robust to major phylogeographical variables, and b) changes in microbial network structure along dietary shifts. We tackled these objectives using the large gut microbiota sequencing dataset available (nine lakes from Africa and America), building geographical and diet-specific networks and performing comparative network analyses.

Results
Major findings indicated that lake and continental microbial networks were highly resembling in global topology and node taxonomic composition, despite the heterogeneity of the samples. A small fraction of the observed co-occurrences among operational taxonomic units (OTUs) was conserved across all lake assemblages. These were all positive associations and involved OTUs within the genera Cetobacterium and Turicibacter and several OTUs belonging to the families of Peptostreptococcaceae and Clostridiaceae (order Clostridiales). Mapping of diet contribution on the African Lake Tanganyika network (therefore excluding the geographic variable) revealed a clear community change from carnivores (C) to omnivores (O) to herbivores (H). Node abundances and effect size for pairwise comparisons between diets supported a strong contrasting pattern between C and H. Moreover, diet-associated nodes in H formed complex modules of positive interactions among taxonomically diverse bacteria (mostly Verrucomicrobia and Proteobacteria).

Conclusions
Conservation of microbial network topologies and specific bacterial associations across distinct lake assemblages point to a major host-associated effect and potential deterministic processes shaping the cichlid gut microbiota. While the origin and biological relevance of these common associations remain unclear, their persistence suggests an important functional role in the cichlid gut. Among the very diverse cichlids of L. Tanganyika, diet nonetheless represents a major driver of microbial community changes. By intersecting results from predictive network inferences and experimental trials, future studies will be directed to explore the strength of these associations, predict the outcome of community alterations driven by diet and ultimately help understanding the role of gut microbiota in cichlid trophic diversification.
Collaborating with health economists to advance implementation science: a qualitative study
Authors: Barnett Miya L. , Dopp Alex R. , Klein Corinna , Ettner Susan L. , Powell Byron J. , Saldana Lisa 
Published: September 2020

Abstract
Background
Implementation research infrequently addresses economic factors, despite the importance of understanding the costs of implementing evidence-based practices (EBPs). Though partnerships with health economists have the potential to increase attention to economic factors within implementation science, barriers to forming these collaborations have been noted. This study investigated the experiences of health economists and implementation researchers who have partnered across disciplines to inform strategies to increase such collaborations.

Methods
A purposeful sampling approach was used to identify eight health economists and eight implementation researchers with experience participating in cross-disciplinary research. We used semi-structured interviews to gather information about participants’ experiences with collaborative research. Thematic analysis was conducted to identify core themes related to facilitators and barriers to collaborations.

Results
Health economists and implementation researchers voiced different perspectives on collaborative research, highlighting the importance of increasing cross-disciplinary understanding. Implementation researchers described a need to measure costs in implementation studies, whereas many health economists described that they seek to collaborate on projects that extend beyond conducting cost analyses. Researchers in both disciplines articulated motivations for collaborative research and identified strategies that promote successful collaboration, with varying degrees of convergence across these themes. Shared motivations included improving methodological rigor of research and making a real-world impact. Strategies to improve collaboration included starting partnerships early in the study design period, having a shared interest, and including health economists in the larger scope of the research.

Conclusions
Health economists and implementation researchers both conduct research with significant policy implications and have the potential to inform one another’s work in ways that might more rapidly advance the uptake of EBPs. Collaborative research between health economists and implementation science has the potential to advance the field; however, researchers will need to work to bridge disciplinary differences. By beginning to develop strong working relationships; increasing their understanding of one another’s disciplinary culture, methodology, and language; and increasing the role economists have within research design and execution, both implementation researchers and health economists can support successful collaborations and robust and informative research.
Meloxicam quantification in rabbit plasma by RP-HPLC: optimization and application to pharmacokinetic study
Authors: Salunkhe Nitin , Jadhav Namdeo , Bhinge Somnath 
Published: September 2020

Abstract
Background
The goal of the proposed study was to validate a rapid, simple, an accurate, robust, and sensitive bioanalytical method for quantifying Meloxicam and Lornoxicam (as internal standard) in rabbit plasma.

Result
Limit of detection and limit of quantification for Meloxicam were found to be 0.0081 and 0.1035 μg mL−1, respectively. The bioanalysis was continued according to standard guidelines and successfully used for bioavailability studies of meloxicam after single dose administration of pure drug and the formulation in rabbit plasma. Finally, obtained results proved its simplicity and an efficiency to be applied for the therapeutic drug monitoring and bioequivalence studies.

Conclusion
Therefore, the set RP-HPLC bioanalysis is simple, convenient, and acceptable to analyze meloxicam in bulk and pharmaceutical formulations in rabbit plasma.

Graphical abstract
Effects of short-term fasting on spontaneous activity and excess post-exercise oxygen consumption in four juvenile fish species with different foraging strategies
Authors: Li Xiuming , Zhang Yaoguang , Fu Shijian 
Published: September 2020

ABSTRACT
To investigate the effects of short-term fasting on spontaneous activity and excess post-exercise oxygen consumption (EPOC) in sit-and-wait carnivorous southern catfish (Silurus meridionalis), active carnivorous black carp (Mylopharyngodon piceus), active herbivorous grass carp (Ctenopharyngodon idellus) and active filter-feeding silver carp (Hypophthalmichthys molitrix), each species was divided into a control group and a fasting group (deprived of food for 14 days). Both groups were maintained at 25°C and, at the end of the experimental period, the total movement distance (TMD), percent time spent moving (PTM), ventilation frequency (Vf), pre-exercise oxygen consumption (M(•)O2) and EPOC response of the experimental fish were measured. The TMD and PTM obtained for the control group of southern catfish were lower than those found for the control groups of the three active species. Short-term fasting resulted in decreases in the TMD and PTM of the southern catfish and black carp and increases in the TMD of grass carp and silver carp. The Vf of southern catfish was significantly higher than those of grass carp and silver carp, whereas the latter was also significantly higher than that of black carp. Short-term fasting resulted in significant increases in the Vf and decreases in the pre-exercise M(•)O2 of southern catfish and silver carp. Southern catfish and black carp exhibited lower peak post-exercise M(•)O2 and recovery rates, and relatively higher EPOC magnitudes than grass carp and silver carp. Short-term fasting exerted no significant effects on the peak post-exercise M(•)O2, but resulted in relatively higher EPOC magnitudes in the four fish species. These results suggest that (1) different fish species exhibit significantly different levels of spontaneous activity and post-exercise M(•)O2 profiles with different characteristics and that (2) short-term fasting exerts different effects on the level of spontaneous activity in four fish species with different foraging strategies.
Genotype frequency and use of single nucleotide polymorphisms for detection of informative allele by polymerase chain reaction
Authors: Nayyar Ayesha , Ahmed Suhaib 
Published: September 2020

Objective: To determine genotype frequency of biallelic single nucleotide polymorphisms and its use in detection of informative allele in donor/recipient pairs (sibling pairs) having undergone haematopoietic stem cell transplantation with various haematological disorders using a PCR based method.
Methods: This descriptive study was conducted at GRC Lab Rawalpindi from Jan 2018 - Oct 2019. A total of twenty donor/ recipient pairs (sibling pairs) were studied for genotype frequency and informativeness of single nucleotide polymorphisms. Genomic DNA was extracted from the peripheral blood and amplification of single nucleotide polymorphisms was done by PCR based method. The amplified DNA was seen by electrophoresis on 6% polyacrylamide gel.
Results: A sharp band of DNA on the polyacrylamide gel indicated a positive reaction. At least two or more informative SNP markers were found in every sibling pair.
Conclusion: Our results demonstrate that PCR amplification of polyacrylamide gel electrophoresis using single nucleotide polymorphism has allowed the successful screening and detection of informative allele in all the donor/recipient pairs. (Sibling pairs). This PCR based assay using SNPs appears to be a quick, simple, reliable and technically feasible method for a use in a Pakistani setting.
doi: https://doi.org/10.12669/pjms.36.7.2998
How to cite this:Nayyar A, Ahmed S. Genotype frequency and use of single nucleotide polymorphisms for detection of informative allele by polymerase chain reaction. Pak J Med Sci. 2020;36(7):1567-1571. doi: https://doi.org/10.12669/pjms.36.7.2998
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Thoughtful surgical practice for therapeutic self: A randomized control trial
Authors: Fatima Tausief , Khan Rehan Ahmed , Azher Faryal , Mahboob Usman 
Published: September 2020

Objectives: To determine the role of structured reflection in teaching basic surgical skills in undergraduate students.
Methods: A randomized control trial was done in two medical colleges of Punjab, from January to December 2017 in which participants were divided into two groups through stratified random sampling. Structured reflection was done by interventional group after training. Post-test was taken to assess their surgical skills. Independent t-test compared the mean of two groups. One-way ANOVA was calculated to measure the difference within the different sub-categories of experimental group.
Results: Out of 140 students that participated in the study, 138 students stayed till the end (retention rate 98.5%, attrition rate 1.5%). Independent t-test (p-value = 0.01) showed statistically significant difference in both control and interventional groups. One-way ANOVA with robust test of equality of Means showed a positive relationship of reflective capacity and acquisition of surgical skills.
Conclusion: The novices who demonstrates better reflective capacity exhibit better acquisition of surgical skills.
doi: https://doi.org/10.12669/pjms.36.7.3038
How to cite this:Fatima T, Khan RA, Azhar F, Mahboob U. Thoughtful surgical practice for therapeutic self: A randomized control trial. Pak J Med Sci. 2020;36(7):1466-1470. doi: https://doi.org/10.12669/pjms.36.7.3038
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Bachs Bibliothek. Eine Weiterführung der Arbeit von Hans Preuß
Authors: Wilhelmi Thomas 
Published: September 2020

Auf der Grundlage neuer bibliografischer Untersuchungen wurde eine vollständige Auflistung der theologischen Werksammlung Bachs erstellt. Mit diesem Katalog werden zahlreiche Lücken bei der Identifizierung von Büchern geschlossen und vollständige Titelzitate, kurze Zusammenfassungen sowie Quellorte angegeben. (Übertragung des englischen Resümees am Ende des Bandes)

Vergleiche auch: Werner Neumann: Zur Frage der Gesangbücher Johann Sebastian Bachs. BJ 1956, S. 112-123
Robin A. Leaver: Bach und die Lutherschriften seiner Bibliothek. BJ 1975, S. 124-132
"Ein Sammelband aus Johann Peter Kellners Besitz"
Authors: Stinson Russell 
Published: September 2020

Das nahezu 400 Seiten umfassende Konvolut SBB Mus. ms. P 804 zählt zu den wichtigsten Quellen für die Instrumentalmusik J. S. Bachs. Der Artikel bietet ein Inventar, das auf Grundlage neuer Forschungen erstmals eine Übersicht zu Inhalt, Originaltiteln, Papiersorten, Schreibern, Vorlagen und Datierungen gibt. Zwei Anhänge geben darüber hinaus Auskunft zu weiteren Bach-Abschriften Johann Peter Kellners und Wolfgang Nicolaus Meys.

Erwähnte Artikel: Hartwig Eichberg: Unechtes unter Johann Sebastian Bachs Klavierwerken. BJ 1975, S. 7-49
Andreas Glöckner: Neuerkenntnisse zu Johann Sebastian Bachs Aufführungskalender zwischen 1729 und 1735. BJ 1981, S. 43-76
Yoshitake Kobayashi: Zur Chronologie der Spätwerke Johann Sebastian Bachs. Kompositions- und Aufführungstätigkeit von 1736 bis 1750. BJ 1988, S. 7-72
Zu Johann Sebastian Bachs Hallenser Probestück von 1713
Authors: Dürr Alfred 
Published: September 2020

Der Beitrag setzt sich mit der von Friedrich Chrysander 1858 aufgebrachten Vermutung auseinander, J. S. Bach habe bei seiner Bewerbung in Halle die Kantate Ich hatte viel Bekümmernis aufgeführt. Die Entstehung und Weiterentwicklung der These wird umrissen, ehe der Autor sich zur seiner Ansicht nach entscheidenden Frage äußert, ob die „Per ogni tempo“ bezeichnete Kantate an einem 2. Adventssonntag, dem Tag der Bach'schen Probeaufführung in Halle, hätte Verwendung finden können und dürfen.

Erwähnte Artikel: Martin Petzoldt: „Die kräfftige Erquickung unter der schweren Angst-Last“. Möglicherweise Neues zur Entstehung der Kantate BWV 21. BJ 1993, S. 31-46
Peter Wollny: Bachs Bewerbung um die Organistenstelle an der Marienkirche zu Halle und ihr Kontext. BJ 1994, S. 25-39
Ein frühes Schriftzeugnis aus Carl Philipp Emanuel Bachs Berliner Zeit
Authors: Wollny Peter 
Published: September 2020

Der Beitrag bemüht sich um die Erhellung der frühen Berliner Jahre C. P. E. Bachs und stellt dazu ein Archivdokument vor. Das Gutachten einiger Berliner Hofmusiker im Zusammenhang mit der Wiederbesetzung der Organistenstelle an St. Nikolai enthält auch einen eigenständigen autografen Passus C. P. E. Bachs vom 4. Juni 1741.

Erwähnter Artikel: Ulrich Leisinger, Peter Wollny: „Altes Zeug von mir“. Carl Philipp Emanuel Bachs kompositorisches Schaffen vor 1740. BJ 1993, S. 127-204
Vergleiche auch: Christoph Henzel: Neues zum Hofcembalisten Carl Philipp Emanuel Bach. BJ 1999, S. 171-178
Bach, Telemann und das Fanfarenthema
Authors: Boyd Malcolm 
Published: September 2020

Im Anschluss an einen Artikel Klaus Hofmanns im BJ 1995 (Link s.u.) trägt der Artikel weitere Beispiele des fraglichen Themas aus Werken Bachs zusammen und stellt eine weitere ähnliche Motivik bei Telemann vor.

Erwähnter Artikel: Klaus Hofmann: "Großer Herr, o starker König" – Ein Fanfarenthema bei Johann Sebastian Bach. BJ 1995, S. 31-46
Vergleiche auch: Klaus Hofmann: Nochmals: Bachs Fanfarenthema. BJ 1997, S. 177-180