bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of integrated antenatal care implementation in primary health care
Authors: Afrizal Sandra Hakiem , Hidayanto Achmad Nizar , Handayani Putu Wuri , Besral Besral , Martha Evi , Markam Hosizah , Budiharsana Meiwita , Eryando Tris 
Published: March 2020

PurposeThis study was aimed to evaluate the implementation of an integrated antenatal care (ANC) scheme through a retrospective document study using a checklist for measuring the adequacy of the cohort ANC register documented by midwives in an urban area and to describe the barriers for the midwives during the ANC record process.Design/methodology/approachAn exploratory descriptive study using a sequential mixed method was utilised where a quantitative method was employed by collecting secondary data of 150 entries of the cohort ANC register and followed by in-depth interviews among midwives and community health workers.FindingsThe results show that the cohort registry indicators for integrated care such as laboratory and management were poorly recorded. Several barriers were found and categorised during the implementation of the integrated ANC, namely (1) governance and strategy, (2) process of care, (3) organisation and management support.Research limitations/implicationsThe contribution of this present research is that it provides empirical data of the integrated ANC implementation in primary health care (PHC) which has the responsibility to deliver an integrated level of care for ANC using a cohort registry for pregnancy registration monitoring which facilitates the continuity and quality of care.Practical implicationsPractical implication of the finding is that functional integration such as the clinical information system to facilitate an efficient and effective approach during the implementation of integrated ANC in primary care should be considered to support the clinical, professional, organisational, system and normative integration.Originality/valueSince only limited studies have been conducted to assess the quality of the cohort ANC registry and to investigate the barriers against integrated ANC implementation in Indonesia, the research findings are valuable information for the national and local governments to improve the ANC service in Indonesia.
Compulsory purchase and the state redistribution of land
Authors: Mitchell Edward 
Published: March 2020

Purpose
The compulsory purchase of land forms the subject of much legal and urban regeneration research. However, there has been little examination of the contractual arrangements between local authorities and private sector property developers that often underpin the compulsory purchase process. This paper aims to examine local authority/private developer contractual behaviour in this context.

Design/methodology/approach
An empirical examination of property development contracts made for the “Silver Hill” project in Winchester, a small city in southern England, and the Brent Cross shopping centre extension in north London. Drawing on Macneil’s (1983) relational contract theory, the paper analyses key contract terms and reviews local authority documentation related to the implementation of those terms.

Findings
The contracts had two purposes as follows: to provide a development and investment opportunity through the compulsory purchase and redistribution of private land; and to grant the private developers participating in the projects freedom to choose if they wished to take up that opportunity. While the contracts look highly “relational”, the scope for flexibility and reciprocity is both carefully planned and tightly controlled. This exposes an asymmetric power imbalance that emerges in and is rearticulated by this type of contractual arrangement.

Originality/value
The empirical analysis of contract terms and contractual behaviour provides a rare opportunity to scrutinise the local authority-private developer relationship underpinning both property development practice and compulsory purchase.
Get Give Make Live
Authors: Toscher Ben , Dahle Yngve , Steinert Martin 
Published: March 2020

PurposeThis study aims to explore the motivations and business ideation processes of 776 entrepreneurs from three diverse cohorts of technology, youth and arts entrepreneurs.Design/methodology/approachUsing an inductive approach inspired by grounded theory, observations resultant from the use of a Web-based digital test environment are openly coded, in which 776 individual entrepreneurs have stated their objectives for engaging in entrepreneurship and performed a business ideation process.FindingsThe study inductively derives a typology of objectives types – “GET GIVE MAKE LIVE” – and finds that beyond the pursuit of profitable opportunities, there is considerable variation, complexity and combinations to the reasons why individuals engage in entrepreneurship. A total of 76 percent of the population in this study have more than one objective, with 48% having more than one type of objective. While the arts entrepreneurs tended to engage in entrepreneurship to “LIVE” and the tech entrepreneurs were more inclined to “GET,” the most frequently observed objective type in all cohorts was to “MAKE.” A total of 74 percent of the entrepreneurs took an effectual approach and began defining their business idea with their core competency, yet technology entrepreneurs were the most likely to start by defining their key market.Practical implicationsEntrepreneurship educators, trainers and helpers should refrain from a standardized approach which assumes that entrepreneurs share the same set of singular motivations. Interventions might benefit from a student-centered program which promotes reflection and articulation of the entrepreneurs’ objectives and their diversity.Originality/valueThis study answers the call for research to embrace entrepreneurial diversity and compliment previous explorations of entrepreneurs’ motivations through an empirically grounded study of three diverse cohorts of entrepreneurs.
Impact of international tourism receipts on public revenue in developed and developing countries
Authors: Gnangnon Sena Kimm 
Published: March 2020

Purpose
This paper aims to investigate empirically how international tourism receipts influence public revenue, in particular non-resource revenue.

Design/methodology/approach
The analysis relies on an unbalanced panel of 156 countries (including both developed and developing countries) over the period 1995-2015. The empirical analysis uses the two-step system generalized methods of moments estimator.

Findings
The empirical results show that international tourism receipts exert a positive and significant impact on non-resource tax revenue. In addition, this effect increases as countries' development levels rise, which signifies that in terms of non-resource tax revenue, an increase in international tourism receipts benefit much more to advanced economies than to less advanced economies.

Research limitations/implications
These findings call for governments notably in developing countries to develop the tourism sector and concurrently to strengthen tax administrations (and possibly design appropriate tax policy for the tourism sector) to derive the full advantage in terms of public revenue from the rise in international tourism receipts.

Practical implications
The analysis highlights the importance of international tourism receipts for public revenue. This would help scholars and policymakers have a clearer view, at least in terms of magnitude, on the impact of international tourism receipts on non-resource tax revenue.

Originality/value
To the best of the author’s knowledge, this is first the study that investigates this topic.
The Impact of Governmental Intervention on the Association Between Initial Public Offering and Future Stock Issuance
Authors: Gounopoulos Dimitrios , Guney Yilmaz , Leng Jingsi , Patsika Victoria 
Published: March 2020

AbstractWe examine the effect of initial public offering (IPO) characteristics on seasoned equity offering (SEO) decisions in relation to governmental intervention in China. Our results confirm the process of underpriced IPOs in promoting earlier and larger SEOs in the Chinese context. The study examines three channels through which the Chinese government intervenes in equity issuance activities, namely state ownership, politically connected executives and economic development areas. We find that the connection between IPOs and SEOs becomes less apparent in government‐intervened firms. We attribute these results to the conflict between the state and minority shareholders, which leads to high uncertainty and risk in government‐intervened firms.
Multispectral imaging for predicting the water status in mushroom during hot‐air dehydration
Authors: Younas Shoaib , Liu Changhong , Qu Hao , Mao Yu , Liu Wei , Wei Liyang , Yan Ling , Zheng Lei 
Published: March 2020

AbstractIn‐depth understanding of the shifting of water status during dehydration is crucial for obtaining better quality of dried food. In this work, we report a nondestructive method to measure the water status in hot‐air dried mushroom via multispectral imaging (MSI) technology combined with chemometric methods. The low‐field nuclear magnetic resonance (LF‐NMR) measurements were performed as reference. During drying process, the moisture content changed dramatically with notable migration and conversion of different water phases. Partial least squares (PLS), back propagation neural network (BPNN), and least squares‐support vector machine (LS‐SVM) models were applied to develop quantitative models. Among all, BPNN model showed considerably better performance of prediction with coefficient of determination R2c = 0.9829, R2p = 0.9639. The results demonstrated that MSI technology combined with chemometric methods is an impressive approach for determination of the water status in hot‐air dried mushrooms, which would facilitate infield of food processing by providing applicable and appropriate platform.Practical ApplicationExperimental investigation of different water status during food processing. Assessment of the potential of multispectral imaging to predict water status. Usage of novel measurement method for food processors.
Antioxidant, α‐amylase and α‐glucosidase activity of various solvent fractions of I. obliquus and the preventive role of active fraction against H2O2 induced damage in hepatic L02 cells as fungisome
Authors: Gao Xudong , Santhanam Ramesh Kumar , Xue Zihan , Jia Yanan , Wang Yajie , Lu Yangpeng , Phisalaphong Muenduen , Chen Haixia 
Published: March 2020

AbstractInonotus obliquus is a traditional mushroom well known for its therapeutic value. In this study, various solvent fractions of I. obliquus were preliminarily screened for their antioxidant, α‐amylase and α‐glucosidase inhibition properties. To improve the drug delivery, the active fraction (ethyl acetate fraction) of I. obliquus was synthesized into fungisome (ethyl acetate phophotidyl choline complex, EAPC) and its physical parameters were assessed using Fourier transform infrared spectroscopy (FTIR), High performance liquid chromatography (HPLC), Scanning electron microscope (SEM), and ς potential analysis. Then normal human hepatic L02 cells was used to evaluate the cytotoxicity of EAPC. The results showed that EA fraction possesses significant free radical scavenging, α‐amylase and α‐glucosidase inhibition properties. FTIR, SEM, and HPLC analysis confirmed the fungisome formation. The particle size of EAPC was 102.80 ± 0.42 nm and the ς potential was −54.30 ± 0.61 mV. The percentage of drug entrapment efficiency was 97.13% and the drug release rates of EAPC in simulated gastric fluid and simulated intestinal fluid were 75.04 ± 0.29% and 93.03 ± 0.36%, respectively. EAPC was nontoxic to L02 cells, however it could selectively fight against the H2O2 induced oxidative damage in L02 cells. This is the first study to provide scientific information to utilize the active fraction of I. obliquus as fungisome.Practical ApplicationsInonotus obliquus (IO) is a traditional medicinal fungus. The extracts of IO have obvious antioxidant and hypoglycemic activities. Ethyl acetate (EA) fraction of IO was encapsulated in liposomes to form EAPC. EAPC has a sustained‐release effect. It has nontoxic to L02 cells and could protect L02 cells from oxidative damage caused by hydrogen peroxide. This study could provide new ideas for the treatment of diabetes.
‘Got together in a riotous and tumultous manner’: Crowds and the Palace of Westminster, c.1700‐1800
Authors: Eagles Robin 
Published: March 2020

AbstractThe old palace of Westminster was a porous complex of medieval buildings and later additions. At times such a heterogeneous agglomeration prompted concerns about guarding Parliament's privileged spaces. This was true for public events such as state trials held in Westminster Hall but also during moments of high political tension such as the Wilkeite disturbances and Gordon Riots. This article considers the topography of the palace and assesses the relative openness of this space, how this made Parliament vulnerable to crowds and to being crowded, and the measures taken to ensure the palace's security from internal and external pressures.
The role of the insula in internet gaming disorder
Authors: Turel Ofir , He Qinghua , Wei Lei , Bechara Antoine 
Published: March 2020

AbstractInternet gaming disorder (IGD) is a concerning issue that requires further research. Here, we seek to examine its neural etiology with an emphasis on the role of the insula. To do so, we relied on the tripartite neurocognitive model of addictive behaviors as applied to IGD. We hypothesized that (a) video game cues will elicit stronger reward system activation and weaker prefrontal activation in gamers vs controls, (b) the IGD scores of gamers will be positively associated with activation of the reward system and negatively with activation of prefrontal regions, (c) deprivation from video gaming will result in increased activation of the insula, when gamers are exposed to video game cues vs to neutral cues, and (d) in deprivation conditions, there will be positive and negative coupling, respectively, between activation of the insula and the reward and prefrontal regions in gamers. We tested these hypotheses with a design with one between‐subjects factor (gamers vs controls) and two within‐subjects factors: stimuli (gaming vs neutral; for all participants) and session (deprivation vs satiety; only for gamers). Findings based on functional magnetic resonance imaging (fMRI; applied to all 52 subjects, 26 gamers, and 26 controls) and psychophysiological interaction (PPI; applied to the 26 gamers) engaged in a video reactivity task supported our assertions. The IGD score positively correlated with activity in the right ventral striatum and negatively with activity in the right dorsolateral prefrontal cortex (DLPFC). Left insular cortex activity was the highest when observing video gaming cues under deprivation. Lastly, there was an increased coupling between the left insula and left ventral striatum and a decreased coupling with left DLPFC when observing video gaming cues compared with when watching control videos in the deprivation condition.
Smoking and snuff use in pregnancy and the risk of asthma and wheeze in pre–schoolchildren—A population‐based register study
Authors: Lundholm Cecilia , Gunnerbeck Anna , D'Onofrio Brian M , Larsson Henrik , Pershagen Göran , Almqvist Catarina 
Published: March 2020

AbstractBackgroundAssociations between tobacco smoking during pregnancy and offspring asthma have been observed, but the role of nicotine and familial factors remains unclear.ObjectiveTo estimate the association between tobacco use in pregnancy, both smoking and Swedish oral moist snuff, and asthma/wheeze in the offspring, how it varies by the child's age and explore the influence of measured and unmeasured familial confounding.MethodsRegister‐based cohort study with sibling comparisons. The cohort included 788 508 children, born in Sweden 2005‐2012 with information on maternal tobacco use in pregnancy, followed until December 2015. Asthma was based on a validated algorithm using asthma diagnoses from hospital visits and prescribed asthma drugs from nation‐wide registers, both as incident asthma/wheeze in age 0‐8 years and current asthma at ages 2, 3, 4, 5 and 6 years.ResultsFor smoking during pregnancy (SDP), we saw a pattern with higher hazard ratios for asthma/wheeze around ages 5 and 18 months. Snuff did not show the same pattern. For current asthma, we saw the strongest association at age 2 years (adjOR = 1.22, 95% CI: 1.17‐1.28), for snuff it was weaker (adjOR = 1.06, 95% CI: 0.96‐1.18). When using sibling controls, the estimates for SDP were clearly attenuated, albeit with wide confidence intervals.Conclusion and clinical relevanceWe saw an association between SDP and asthma at early age. The association with snuff was clearly weaker. The associations with SDP were attenuated when adjusting for measured and unmeasured familial factors shared by siblings. Based on those results, nicotine seems to have a limited role in the association between SDP and asthma; rather environmental tobacco smoke and other familial factors seem to explain observed associations.
Segregation of caffeine reward and aversion in the rat nucleus accumbens shell versus core
Authors: Yee Mandy , Maal‐Bared Geith , Ting‐A‐Kee Ryan , Chwalek Michal , Mackay‐Clackett Isabel , Bergamini Michael , Grieder Taryn E. , van der Kooy Derek 
Published: March 2020

AbstractCaffeine, the most commonly consumed psychoactive drug in the world, is readily available in dietary sources, including soft drinks, chocolate, tea and coffee. However, little is known about the neural substrates that underlie caffeine's rewarding and aversive properties and what ultimately leads us to seek or avoid caffeine consumption. Using male Wistar rats in a place conditioning procedure, we show that systemic caffeine at a low intraperitoneal dose of 2 mg/kg (or 100 µM injected directly into the rostral, but not caudal, portion of the ventral tegmental area) produced conditioned place preferences. By contrast, high doses of systemic caffeine at 10 and 30 mg/kg produced conditioned place aversions. These aversions were not recapitulated by a caffeine analog restricted to the periphery. Both caffeine reward and aversion were blocked by systemic D1‐like receptor antagonism using SCH23390, while systemic D2‐like receptor antagonism with eticlopride had smaller effects on caffeine motivation. Most important, we demonstrated that pharmacological blockade of dopamine receptors using α‐flupenthixol injected into the nucleus accumbens shell, but not core, blocked caffeine‐conditioned place preferences. Conversely, α‐flupenthixol injected into the nucleus accumbens core, but not shell, blocked caffeine‐conditioned place aversions. Thus, our findings reveal two dopamine‐dependent and functionally dissociable mechanisms for processing caffeine motivation, which are segregated between nucleus accumbens subregions. These data provide novel evidence for the roles of the nucleus accumbens subregions in mediating approach and avoidance behaviours for caffeine.
Neuroinflammation and depression: A review
Authors: Troubat Romain , Barone Pascal , Leman Samuel , Desmidt Thomas , Cressant Arnaud , Atanasova Boriana , Brizard Bruno , El Hage Wissam , Surget Alexandre , Belzung Catherine , Camus Vincent 
Published: March 2020

AbstractSome recent clinical and preclinical evidence suggests that neuroinflammation is a key factor that interacts with the three neurobiological correlates of major depressive disorder: depletion of brain serotonin, dysregulation of the hypothalamus–pituitary–adrenal (HPA) axis and alteration of the continuous production of adult‐generated neurons in the dentate gyrus of the hippocampus. This review discusses the main players in brain immunity as well as how inflammation interacts with the above three mechanisms. It is reported that kynurenine (KYN) pathway alteration in favour of its excitotoxic component and HPA axis dysregulation have the common effect of increasing extracellular glutamate levels and glutamate neurotransmission, which can impact hippocampal neurogenesis. This pathophysiological cascade appears to be triggered or sustained and reinforced by any chronic inflammatory condition involving increased circulating markers of inflammation that are able to cross the blood–brain barrier and activate microglia; it can also be the consequence of primary brain neuroinflammation, such as in neurodegenerative disorders with early manifestations that are frequently depressive symptoms. Further recent data indicate that primary microglial activation may also result from a direct impact of chronic stress on vascular function. The intricated dynamic crosstalk between neuroinflammation and other relevant neurobiological correlates of depression add to evidence that neuroinflammation may be a key therapeutic target for future therapeutic strategies in major depressive disorder.
The logic behind Quine's criterion of ontological commitment
Authors: Smid Jeroen 
Published: March 2020

AbstractThis article first explains why Quine took first‐order classical logic to be the only language in which we should formulate a theory or declarative statement to determine its ontological commitments. I then argue that Quineans cannot relax Quine's restriction to classical logic such thatanynonclassical logic may be used to uncover a theory's ontological commitments. The reason is that this leads to radical ontological relativism according to which the ontological commitments of a theory are relative to a logic. This is not a Quinean picture of ontology, but a Carnapian one. Finally, I consider whether Quineans can go beyond Quine by allowing for classical and plural logic, but no other logics. I claim that this is not possible because plural logic is not transparent: it allows for ontologically nonequivalent theories to be formulated such that they come out as ontologically equivalent.
Limits to wealth in the history of Western philosophy
Authors: Kramm Matthias , Robeyns Ingrid 
Published: March 2020

AbstractIn contemporary political philosophy, it has recently been proposed that upper limits should be put on individual wealth acquisition. In this article, we discuss the arguments made by canonical writers in the history of economic and political philosophy about ideas that can be considered prototypes of limitarianism. In contemporary discussions, a distinction has been made between intrinsic and non‐intrinsic limitarianism, whereby it has been doubted that, in present‐day pluralistic societies, the former can be justified. We have found proto‐limitarian claims or justifications for limitarianism in four moral domains: moral psychology, moral reasoning, virtue ethics and political morality. While in the present‐day context, the view that there should be an upper limit to wealth may sound much too radical, we show that throughout history, many influential philosophers made limitarian or proto‐limitarian claims, including many intrinsic arguments for wealth limitarianism. We end the article by outlining the implications of those historical insights for systematic contemporary discussions of limitarianism.