bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vivo production of entomopathogenic nematodes using Galleria mellonella: costs and effect of diets on nematode pathogenicity
Authors: Kotchofa Régina , Baimey Hugues 
Published: December 2019

Abstract
Five separate diets – beeswax (BW), glycerol (Gly), and three types of dog croquettes (DC1, DC2, and DC3) – were used to rear larvae of the greater wax moth, Galleria mellonella. The larvae were later inoculated with five different isolates of entomopathogenic nematodes (EPN) emerging from the insect larvae reared on the five diets. Insect cadavers were then conserved for 1, 2, 3, and 4 wks (T1, T2, T3, and T4, respectively) to evaluate the nematodes’ progeny production and to assess the pathogenicity of emerging nematodes to G. mellonella larvae. Larvae fed on DC1 weighed the least (0.18 ± 0.03 g) and those fed on Gly weighed the most (0.22 ± 0.04 g). Gly was effective for insect development but was the most expensive to produce at 6.30 US dollars/kg. No significant difference (P = 0.851) was observed between mortality rates of larvae for nematode isolates for the three best diets (Gly, BW, and DC1) during 1 wk (T1) and 3 wks (T3) after processing at 3 d post-inoculation. All nematode isolates emerged and had the highest population density per insect larva at T1 for isolate Ze4 (Heterorhabditis sonorensis) on BW (553.63 ± 311.97 infective juveniles (IJs)/50 μ l of suspension, 276,815 IJs/larva) and at T2 on DC1 (488.63 ± 321.37 IJs/50 μ l, 244,315 IJs/larva) and for isolate Aglali (H. sonorensis) at T1 on Gly (615.18  ±  309.63 IJs/50 μ l, 307,590 IJs/larva). This study shows the costs and effectiveness of different diets on development and production of G. mellonella larvae and the EPN produced in vivo.
The problem of patient compliance with treatment for respiratory infections
Authors: Zaytsev A. A. , Sinopalnikov A. I. 
Published: December 2019

Patient compliance describes the degree, to which a patient follows treatment regimen. At present, non-compliance with medical recommendations is one of the key problems for outpatient practice. Even in case of respiratory infections, patients often violate the prescribed treatment regimen, which leads to growth of ineffective treatment cases, complications, and is also accompanied by a high risk of selection of drug-resistant infectious organisms and rise in expenditures for managing patients. The most common mistakes made by patients include the change by patients of the prescribed antibiotic dosing regimen and premature termination of antimicrobial therapy. Factors affecting patient compliance are extremely diverse. Among them are factors associated with treatment and a disease, patient-associated factors of «doctor - patient» contact, and demographic predictors of low compliance, drug dosage frequency. The most important factors affecting adherence to treatment are duration of therapy; drug tolerance/safety; dosage forms (tablets, syrup, sachet); patient confidence in medical recommendations (presence of «doctor - patient» relationship); severity of the disease; patient age and sex; social activity/employment of the patient; social status of the patient, level of education; marital status; presence of a concomitant pathology in the patient; presence of bad habits (smoking, alcohol) in the patient. The main factor affecting the compliance with therapy is the drug dosage frequency. It is known that compliance is highest, if a patient is required to take a single dose of the drug per day. Duration of therapy is another important factor affecting the patient compliance. For instance, pharmacotherapy for 7 days is characterized by better compliance compared to longer antibiotic treatment regimens. Methods of improving compliance with antimicrobial therapy: reduction in the drug dosage frequency; short courses of antibiotic therapy; favourable safety profile; the cost of the drug; a patient-friendly form of antibiotic dosage form; patient education, clear information of the patient; monitoring the treatment process (repeat visits, phone contacts, etc.). The most effective way to increase compliance is to use an antibiotic drug 1-2 times per day. The use of short antibiotics courses (less than 7 days) is also a good way to increase adherence to treatment. The use of antibiotics with a good safety profile is another important approach to improving the compliance. The article also discusses other ways to enhance the patient compliance with the treatment for respiratory infections.
β-amyloid and Oxidative Stress: Perspectives in Drug Development
Authors: Caruso Giuseppe , Spampinato Simona F. , Cardaci Vincenzo , Caraci Filippo , Sortino Maria A. , Merlo Sara 
Published: December 2019

:Alzheimer’s Disease (AD) is a slow-developing neurodegenerative disorder in which the main pathogenic role has been assigned to β-amyloid protein (Aβ) that accumulates in extracellular plaques. The mechanism of action of Aβ has been deeply analyzed and several membrane structures have been identified as potential mediators of its effect. The ability of Aβ to modify neuronal activity, receptor expression, signaling pathways, mitochondrial function, and involvement of glial cells have been analyzed. In addition, extensive literature deals with the involvement of oxidative stress in Aβ effects. Herein we focus more specifically on the reciprocal regulation of Aβ, that causes oxidative stress, that favors Aβ aggregation and toxicity and negatively affects the peptide clearance. Analysis of this strict interaction may offer novel opportunities for therapeutic intervention. Both common and new molecules endowed with antioxidant properties deserve attention in this regard.
A Novel Modified Artificial Bee Colony for DOA Estimation
Authors: Parsa Seyed Ahmadreza Hashemi , Zadeh Ataolah Ebrahim , Kazemitabar Seyed Javad 
Published: December 2019

Aims:
We consider the Direction of Arrival (DOA) estimation for code division multiple
access (CDMA) signals. Background: Solving this problem requires non-linear optimization
and thus the speed of convergence becomes crucial.

Objective:
A novel Modified Artificial Bee Colony (MABC) has been proposed. We use secondorder
Taylor series expansion of the cost function to ameliorate the searchability of artificial bee
colony (ABC) for finding the globally optimal solution.

Methods:
The main idea is to harness the exploration and exploitation features. The optimum point
of second-order Taylor expansion of cost function is used as a velocity factor of the ABC algorithm.

Results:
The proposed technique is used for solving the DOA estimation problem of a CDMA
system. Simulation results confirm the performance improvement of our proposed algorithm.

Conclusion:
The cost function of the DOA estimation usually leads to a non-linear optimization
problem. Using evolutionary algorithms can improve convergence rate of such problems.
Health Care Consumer Shopping Behaviors and Sentiment: Qualitative Study
Authors: Gordon Deborah , Ford Anna , Triedman Natalie , Hart Kamber , Perlis Roy 
Published: December 2019

Background
Although some health care market reforms seek to better engage consumers in purchasing health care services, health consumer behavior remains poorly understood.

Objective
This study aimed to characterize the behaviors and sentiment of consumers who attempt to shop for health care services.

Methods
We used a semistructured interview guide based on grounded theory and standard qualitative research methods to examine components of a typical shopping process in a sample size of 54 insured adults. All interviews were systematically coded to capture consumer behaviors, barriers to shopping behavior, and sentiments associated with these experiences.

Results
Participants most commonly described determining and evaluating options, seeking value, and assessing or evaluating value. In total, 83% (45/54) of participants described engaging in negotiations regarding health care purchasing. The degree of positive sentiment expressed in the interview was positively correlated with identifying and determining the health plan, provider, or treatment options; making the decision to purchase; and evaluating the decision to purchase. Conversely, negative sentiment was correlated with seeking value and making the decision to buy.

Conclusions
Consumer shopping behaviors are prevalent in health care purchasing and can be mapped to established consumer behavior models.
Flash, Spirit, Plex, Stretch: A Trans-Disciplinary View of the Media Sensorium
Authors: McEwen Rhonda N. 
Published: December 2019

Background This article takes a transdisciplinary view of the media sensorium by applying humanities, social science, and engineering perspectives to the relationships among sensory perception, cognition, and how people come to understand their worlds through the senses. Analysis The goal of this article is to engage with the provocation that the sensorium, a concept that Marshall McLuhan brought to media studies in the 1960s, provides the lens through which we observe that communication is the expression of cognition via the combined potentiality of physiology and technology. “Sensory technologies” are used as analytical vehicles in a technological journey from the Walkman to 21st-century telecommunications. Conclusion and implications The reader is given a call to action to use the full spectrum of the sensorium to locate and act on transformative contemporary processes underway.
URINOTHORAX: AN UNUSUAL CAUSE OF MASSIVE PLEURAL EFFUSION
Authors: Bauza Quetglas Jose Luis , Fullana Maria Isabel , Asensio Javier , Díaz Manuel , Pinheiro A.M. , Asensio Javier , Casu Vasile Cristian , Del Rio Manuel 
Published: December 2019

A 74 year-old male with a history of high blood pressure and hyperuricemia was admitted to the hospital with asthenia, unquantified weight loss, dyspnea on moderate exertion for 2 weeks, and diffuse abdominal pain. Blood leukocyte count was 12400/uL, creatinine 0.98 mg/dL, CRP 19 mg/dL, and LDH 318 U/L. The chest X-ray showed a right pleural effusion and the pleural fluid was suggestive of an exudate. Thorax and abdominal CT scan revealed a polycystic right kidney with grade IV hydronephrosis and suggested the presence of a nephropleural fistula. The thoracocentesis was repeated and the pleural fluid / serum ratio of creatinine obtained was higher than 1 (1.35 mg/dL), which is a diagnostic criterion for urinothorax. Finally, a retrograde pyelography was carried out, and confirmed the passage of urinary tract fluid into the pleural cavity. A thoracic drainage tube and a nephrostomy through the superior calyx were placed, both draining purulent material. One month later, the control CT shows a right atrophic kidney and a reduction of the size of the fistulous path.
Urinothorax is an infrequent and underdiagnosed pathology, with few cases reported. It is usually presented as a transudative pleural effusion. Currently, no test is available to confirm the diagnosis, although the ratio of serum creatinine/pleural creatinine could suggest the presence of urinothorax. Radiographic imaging is useful to support the diagnosis. Management of a urinothorax requires a multidisciplinary approach with an emphasis on the correction of the underlying urinary tract pathology, and once corrected, this often leads to a rapid resolution of the pleural effusion.
Biomijuridika: Pemikiran Ilmu Hukum Pidana Berketuhanan dari Barda Nawawi Arief
Authors: Rustamaji Muhammad 
Published: December 2019

This article discusses the legal thought from Barda Nawawi Arief, named biomijuridika. The concept of biomijuridika is actually an invitation for legal learner to reflect on whether the life of law and the development of law in Indonesia are secular. If jurisprudence contains in it the science of “regulating or arranging”, Barda questioned is not “God Most Regulating and Arranging”, and therefore the law must also be in accordance with God’s teachings. Therefore according to Barda, legal education and legal science in Indonesia should not be secular. Consequently, legal education and national law must also explore and examine the law of the One Godhead. This article shows that in the Indonesian context, the biomijuridika of Barda are actually in line with the Pancasila as the state foundation. On the basis of Pancasila, the life of the nation and state of Indonesia must be based on the Pancasila, which in the life of the law means must, one of them, be based on the One Godhead. However, the legal thought of biomijuridika from Barda still seems to leave a discourse space that seems to have not been answered thoroughly, namely when this concept was proposed as one of the alternative models of legal reform especially in the field of criminal law. Such criticism in particular can be examined in the facets of the development of theoretical and practical law.
Abstrak
Artikel ini membahas pemikiran hukum dari Barda Nawawi Arief yang diberi nama biomijuridika. Konsep biomijuridika sejatinya sebuah ajakan bagi pembelajar hukum untuk merenung tentang apakah kehidupan berhukum dan pengembangan hukum di Indonesia bersifat sekuler. Jika ilmu hukum mengandung di dalamnya ilmu “mengatur atau menata”, Barda mempertanyakan bukankah “Tuhan Maha Mengatur dan Maha Menata”, dan karenanya hukum pun mesti sesuai dengan ajaran Tuhan. Oleh karenanya menurut Barda pendidikan hukum dan ilmu hukum di Indonesia seharusnya tidak bersifat sekuler. Konsekuensinya, pendidikan tinggi hukum dan ilmu hukum nasional harus juga menggali dan mengkaji ilmu hukum berketuhanan Yang Maha Esa. Artikel ini menunjukkan bahwa dalam konteks Indonesia, biomijuridika dari Barda sesungguhnya sejalan dengan dasar negara Pancasila. Dengan dasar negara Pancasila, maka kehidupan berbangsa dan bernegara Indonesia mesti didasarkan pada Pancasila, yang dalam kehidupan berhukum berarti mesti, salah satunya, didasarkan pada “Ketuhanan Yang Maha Esa”. Namun demikian, pemikiran hukum biomijuridika dari Barda tampaknya masih menyisakan ruang diskursus yang agaknya belum dijawab dengan tuntas, yaitu ketika konsep ini diajukan sebagai salah satu model alternatif pembaruan hukum utamanya pada bidang hukum pidana. Kritik demikian khususnya dapat dicermati pada faset pengembanan hukum teoretis dan pengembanan hukum praktis.
GEOGRAFIA DO COTIDIANO: O ENSINO DOS CONTEÚDOS GEOGRÁFICOS MEDIANTE A TÉCNICA DA TEMPESTADE DE IDEIAS
Authors: Tavares Cícero Antonio Jatanael Da Silva 
Published: December 2019

Este artigo aborda sobre o uso da “tempestade de ideias” no ensino de Geografia. Essa técnica é de origem paradidática e ao adequá-la para o ensino, é possível usá-la com os alunos, despertando seus interesses pelos conteúdos mediante problematizações referentes a seus cotidianos e a eventos externos aos seus espaços vividos, desde que abarquem os seus saberes. Assim, esteve proposto a verificação da eficiência desse recurso quanto a essa função pedagógica. Mediante a prática realizada, é plausível efetivar a sua aplicação ao identificar que os alunos se tornaram mais participantivos nas aulas e, consequentemente, aprenderam os conteúdos.
System Analytical Model to Estimate and Optimize Oil Well Performance
Authors: Okologume Wilfred Chinedu , Omars-Ofugara Silver 
Published: December 2019

The use of separated flow models to specify the vertical lift performance of an oil well is usually somewhat complex- due to the many equations and correlations involved in the determination of the required variables. Consequently, coding these models in the computer presents an extent of difficulty. In this study however, with the view of developing a computer model (DOBB) to perform nodal analysis for oil wells, an efficient algorithm was established to facilitate the determination of the operating pressure and liquid flow rate of oil wells (which is the point of intersection between the VLP and IPR curve). More so, Hagedorn Brown model was incorporated into the computer model to account for liquid hold ups and various flow regimes (excluding bubble flow regime) in the tubing string. The computer model developed in this study is equipped with the ability to determine fanning friction factor of the tubing string provided that the roughness of the pipe is known. Also, when the developed computer model was tested with some ranges of data points, nodal analysis plots were obtained from the different data points. Nonetheless, DOBB (a production engineering toolkit developed in this study) was proven to be efficient on the part of performing nodal analysis for oil wells.
ANALISIS BAURAN PEMASARAN DI HOTEL PANGERAN BEACH PADANG
Authors: Widyastuti Nurmala 
Published: December 2019

Abstract. Based on this study to analyze the marketing mix at the Pangeran Beach Hotel Padang. This type of research is a qualitative descripptive. Determination of informants using purposive sampling technique that is many as eight research informants consisting of hotel marketing and hotel consumers. The results obtained from this study are as follows : 1) The products offered by the Pangeran Beach Hotel Padang are quality attractive and of high quality and the service provide to guests are good, 2) The Price set by the Pangeran Beach Hotel Padang is quite high and is only affordable for middle and upper class people, 3) Promotions carried out by the Pangeran Beach Hotel Padang have been maximized so that guests are still intererted in staying at the hotel, 4) The Place or location of the Pangeran Beach Hotel Padang is already strategic annd in the city center, and works together to travel agents so that guests know the location of the Pangeran Beach Hotel Padang.
Keywords : Marketing, Marketing mix
Pengaruh Proporsi Pati Bengkuang dan Tepung Kentang Terhadap Hasil Jadi Masker Perawatan Kulit Wajah
Authors: Amalia Vitri 
Published: December 2019

Facial skin problems such as blemishes, black spots, dull skin, premature aging and so on, require more optimal treatment, one of them using a mask Facial skin masks are one type of traditional cosmetics that can be used as a facial treatment to maintain the health of facial skin, namely by using yam starch and potato flour. The purpose of this study was to describe the various proportions of the results of the yam starch mask and potato flour with indicators of aroma, stickiness and panelist preference level and to analyze comparisons to assess the best proportion. This research is a research with true experimental method. The oup consisted of the results of the masked starch mask and potato flour with the proportion of 10g and 40g (X1), the proportion of 20g and 30g (X2) and the proportion of 30g and 20g (X3). The type of data used in this study is primary data. Data analysis techniques using ANOVA analysis and using Duncan's analysis as a further test. The results of the hypothesis test state that the price of F count> F table (27,271> 3,110) this proves that the hypothesis that reads "There are differences in the proportion of yam and potato starch (10g: 40g), (20g: 30g) and (30g: 20g) starch on the results of the facial skin care mask seen from the aroma, stickiness, and level panelist's preference "received at 95% significancy.
Keywords: masks, starch, potato
PENGUATAN KAPASITAS PEMERINTAH DESA DUNGGALA KECAMATAN TIBAWA MENUJU DESA BERBASIS INFORMATION AND COMMUNICATION TECHNOLOGY
Authors: Dako Amirudin Yunus , Ilham Jumiati 
Published: December 2019

Desa Dunggala terletak di kecamatan Tibawa Kabupaten Gorontalo, memiliki tipologi persawahan dengan klasifikasi desa swakarya pada kategori lanjut. Observasi awal yang telah dilakukan mendapatkan bahwa desa ini belum memiliki dokumen profil desa, monografi desa, peta desa, website desa serta data yang ada tidak menyatu dalam dokumen yang utuh. Pengelolaan data desa sudah dilakukan dengan komputer tetapi masih terpisah-pisah dan menggunakan aplikasi yang berbeda-beda dan tidak sesuai peruntukannya. Program pengabdian ini ditujukan untuk melakukan penguatan kapasitas pemerintah desa dalam mewujudkan desa Dunggala sebagai desa berbasis information and communication technology, melalui serangkaian kegiatan penguatan kapasitas untuk memetakan aset dan sumber daya desa serta analisis kondisi desa untuk dituangkan dalam dokumen profil desa yang komprehensif dan lengkap sesuai ketentuan yang berlaku, dikelola secara berkelanjutan dalam sistem informasi desa berbentuk website sebagai sarana penyampaian informasi yang terakses secara mudah dan global.Setelah melalui serangkaian pelatihan dan pendampingan, pada akhir program pengabdian aparat pemerintah desa telah dapat mengelola data profil desa di dalam sebuah website desa berbasis sistem informasi geografis yang terakses global dan dikelola secara berkelanjutan, yang memuat peta desa, data kependudukan, profil desa, monografi desa, desa dalam angka, dilengkapi modul surat menyurat otomatis dan papan informasi digital.
Uso de magnetometría terrestre en la exploración de pelitas ferruginosas en canteras del Distrito minero Barker, provincia de Buenos Aires
Authors: Tessone Mario , Nigro Joaquín , Perdomo Santiago , Etcheverry Ricardo , Fernández Raúl , Tessone Nicolás , Caballé Marcelo 
Published: December 2019

En la Sierra de La Juanita y la Cuchilla de las Águilas, cercanas a la localidad de Barker, se extraen rocas ferruginosas destinadas a la industria del cemento. La falta de continuidad lateral de los bancos constituye un problema para los productores, tanto en la planificación de la explotación como de la recuperación ambiental. Con el fin de contribuir a la solución o mitigar esta problemática se aplicaron técnicas geofísicas y a partir de ello se realizaron reinterpretaciones geológicas de las áreas. Sobre la base de la información de superficie se planteó la utilización de un método geofísico rápido y de bajo costo, consistente en mediciones de susceptibilidad magnética en las rocas de canteras seleccionadas. Comprobada la respuesta positiva de los niveles ferríferos por sus valores elevados de susceptibilidad, se programó una exploración magnetométrica terreste en el área de influencia de las canteras, con el fin de evaluar su eficacia para detectar en el subsuelo capas con altos tenores de Hierro y ajustar el tratamiento de los datos para la obtención de resultados óptimos.