bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Calcination Temperature on the Structure of Chitosan-Modified Montmorillonites and their Adsorption of Aflatoxin B1
Authors: Lian Chi , Wang Gaofeng , Lv WenQiang , Sun Zhiming , Zheng Shuilin 
Published: February 2020

AbstractChitosan (CTS) modified montmorillonite (Mnt) composites (CTS-Mnt), which have been widely reported for the adsorption of heavy-metal ions and biological dyes, have not been applied to the field of mycotoxin adsorption. The current study was focused on the preparation of CTS-Mnt by calcination as a mycotoxin adsorbent for the efficient removal of aflatoxin B1 (AFB1). The CTS-Mnt samples obtained were characterized using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and nitrogen adsorption/desorption analysis. The CTS-Mnt samples prepared at various calcination temperatures exhibited varying structural configurations, surface hydrophobicities, and texture properties. The results revealed that stable CTS-Mnt speciments, obtained at <350°C, displayed superior adsorption capacity for AFB1 from a simulated gastrointestinal tract, increasing from 0.51 mg/g of raw Mnt to 4.97 mg/g. With increased calcination temperature, the effect of pH on the adsorption process of AFB1 becomes negligible. This study demonstrates that the novel CTS-Mnt has tremendous potential as an AFB1 adsorbent.
Contestation in Multi-Stakeholder Initiatives: Enhancing the Democratic Quality of Transnational Governance
Authors: Arenas Daniel , Albareda Laura , Goodman Jennifer 
Published: February 2020

ABSTRACTThis article studies multi-stakeholder initiatives (MSIs) as spaces for both deliberation and contestation between constituencies with competing discourses and disputed values, beliefs, and preferences. We review different theoretical perspectives on MSIs, which see them mainly as spaces to find solutions to market problems (economic approach), as spaces of conflict and bargaining (political approach), or as spaces of consensus (deliberative approach). In contrast, we build on a contestatory deliberative perspective, which gives equal value to both contestation and consensus. We identify four types of internal contestation which can be present in MSIs—procedural, inclusiveness, epistemic, and ultimate-goal—and argue that embracing contestation and engaging in ongoing revision of provisional agreements, criteria, and goals can enhance the democratic quality of MSIs. Finally, we explore the implications of this perspective for theorizing about the democratic quality in MSIs and about the role of corporations in transnational governance.
Microbial dysbiosis-induced obesity: role of gut microbiota in homoeostasis of energy metabolism
Authors: Amabebe Emmanuel , Robert Faith O. , Agbalalah Tarimoboere , Orubu Ebiowei S. F. 
Published: February 2020

AbstractThe global obesity epidemic has necessitated the search for better intervention strategies including the exploitation of the health benefits of some gut microbiota and their metabolic products. Therefore, we examined the gut microbial composition and mechanisms of interaction with the host in relation to homoeostatic energy metabolism and pathophysiology of dysbiosis-induced metabolic inflammation and obesity. We also discussed the eubiotic, health-promoting effects of probiotics and prebiotics as well as epigenetic modifications associated with gut microbial dysbiosis and risk of obesity. High-fat/carbohydrate diet programmes the gut microbiota to one predominated by Firmicutes (Clostridium), Prevotella and Methanobrevibacter but deficient in beneficial genera/species such as Bacteroides, Bifidobacterium, Lactobacillus and Akkermansia. Altered gut microbiota is associated with decreased expression of SCFA that maintain intestinal epithelial barrier integrity, reduce bacterial translocation and inflammation and increase expression of hunger-suppressing hormones. Reduced amounts of beneficial micro-organisms also inhibit fasting-induced adipocyte factor expression leading to dyslipidaemia. A low-grade chronic inflammation (metabolic endotoxaemia) ensues which culminates in obesity and its co-morbidities. The synergy of high-fat diet and dysbiotic gut microbiota initiates a recipe that epigenetically programmes the host for increased adiposity and poor glycaemic control. Interestingly, these obesogenic mechanistic pathways that are transmittable from one generation to another can be modulated through the administration of probiotics, prebiotics and synbiotics. Though the influence of gut microbiota on the risk of obesity and several intervention strategies have been extensively demonstrated in animal models, application in humans still requires further robust investigation.
GAPS BETWEEN CONSECUTIVE UNTWISTING NUMBERS
Authors: MCCOY DUNCAN 
Published: February 2020

AbstractFor p ≥ 1, one can define a generalisation of the unknotting number tup called the pth untwisting number, which counts the number of null-homologous twists on at most 2p strands required to convert the knot to the unknot. We show that for any p ≥ 2 the difference between the consecutive untwisting numbers tup–1 and tup can be arbitrarily large. We also show that torus knots exhibit arbitrarily large gaps between tu1 and tu2.
A comparative study of extraction techniques for maximum recovery of β-galactosidase from the yogurt bacterium Lactobacillus delbrueckii ssp. bulgaricus
Authors: Gyawali Rabin , Oyeniran Ayowole , Zimmerman Tahl , Aljaloud Sulaiman O. , Krastanov Albert , Ibrahim Salam A. 
Published: February 2020

AbstractThe study reported in this research communication evaluates the chemical (solvents) and mechanical (sonication, bead-beater) extraction methods to determine the maximum recovery of β-galactosidase from L. bulgaricus spp. Among all extraction techniques, sonication-assisted extraction yielded the highest amounts of enzyme activity (between 1892–2156 Miller Units) in cell-free extract (supernatant). Interestingly, solvent extracted enzyme activities were found to be very low (between 83–153 Miller Units) in supernatant. SDS-polyacrylamide gel electrophoresis and the total protein determination showed that mechanical methods can completely lyse the cells. Our results thus demonstrated that the mechanical extraction method of sonication is the best one for recovering the maximum amount of lactase from L. bulgaricus strains.
Reassessment of an introduced cheetah Acinonyx jubatus population in Matusadona National Park, Zimbabwe
Authors: van der Meer Esther , Sousa Lara L. , Loveridge Andrew J. 
Published: February 2020

AbstractTranslocations are used to mitigate human–wildlife conflict, secure population viability of isolated populations and introduce or reintroduce populations in former or new range. With wild species increasingly confined to small patches of habitat embedded in human-dominated landscapes, the use of translocations is likely to increase. The cheetah Acinonyx jubatus is a large carnivore species with a long history of translocations. As for other species, evaluation of the success of cheetah translocations is complicated by a scarcity of published results, especially of failed attempts. Yet, such information is crucial to improve future translocations. A relatively well documented case is the translocation of alleged problem cheetahs into Matusadona National Park, Zimbabwe, in the early 1990s. In this study we used a combination of survey methods to reassess the status of Matusadona's cheetah population and model current occupancy in relation to densities of competing carnivores and altitude. Our findings indicate this cheetah population has effectively been extirpated, highlighting the importance of thorough planning and standardized long-term monitoring of translocated populations for the understanding of the factors that affect translocation success.
Tracking foraging green turtles in the Republic of the Congo: insights into spatial ecology from a data poor region
Authors: Metcalfe Kristian , Bréheret Nathalie , Bal Gaëlle , Chauvet Eva , Doherty Philip D. , Formia Angela , Girard Alexandre , Mavoungou Jean-Gabriel , Parnell Richard J. , Pikesley Stephen K. , Godley Brendan J. 
Published: February 2020

AbstractGlobally, marine turtles are considered threatened throughout their range, and therefore conservation practitioners are increasingly investing resources in marine protected areas to protect key life history stages and critical habitats, including foraging grounds, nesting beaches and inter-nesting areas. Empirical data on the distribution of these habitats and/or the spatial ecology and behaviour of individuals of many marine turtle populations are often lacking, undermining conservation efforts, particularly along the Atlantic coast of Africa. Here we contribute to the knowledge base in this region by describing patterns of habitat use for nine green turtles Chelonia mydas tagged with satellite platform transmitter terminals at a foraging ground in Loango Bay, Republic of the Congo, one of only a few documented mainland foraging grounds for marine turtles in Central Africa. Analyses of these data revealed that core areas of habitat use and occupancy for a wide range of size/age classes were restricted to shallow waters adjacent to Pointe Indienne in Loango Bay, with most individuals showing periods of high fidelity to this area. These data are timely given the Congolese government recently announced its intention to create a marine conservation zone to protect marine turtles in Loango Bay. Despite the small sample size of this study, these data exemplify the need for comprehensive strategies that span national jurisdictions, as we provide the first documented evidence of linkages between green turtle foraging sites in Central Africa (Loango Bay, Republic of the Congo) and Southern Africa (Mussulo Bay, Angola).
Posttraumatic stress disorder symptom trajectories within the first year following emergency department admissions: pooled results from the International Consortium to predict PTSD
Authors: Lowe Sarah R. , Ratanatharathorn Andrew , Lai Betty S. , van der Mei Willem , Barbano Anna C. , Bryant Richard A. , Delahanty Douglas L. , Matsuoka Yutaka J. , Olff Miranda , Schnyder Ulrich , Laska Eugene , Koenen Karestan C. , Shalev Arieh Y. , Kessler Ronald C. 
Published: February 2020

AbstractBackgroundResearch exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics.MethodsThis analysis pooled data from six longitudinal studies of adult survivors of civilian-related injuries admitted to general hospital emergency departments (EDs) in six countries (pooled N = 3083). Each study included at least three assessments of the clinician-administered PTSD scale in the first post-trauma year. Latent class growth analysis determined the proportion of participants exhibiting various PTSD symptom trajectories within and across the datasets. Multinomial logistic regression analyses examined demographic characteristics, type of event leading to the injury, and trauma history as predictors of trajectories differentiated by their initial severity and course.ResultsFive trajectories were found across the datasets: Low (64.5%), Remitting (16.9%), Moderate (6.7%), High (6.5%), and Delayed (5.5%). Female gender, non-white race, prior interpersonal trauma, and assaultive injuries were associated with increased risk for initial PTSD reactions. Female gender and assaultive injuries were associated with risk for membership in the Delayed (v. Low) trajectory, and lower education, prior interpersonal trauma, and assaultive injuries with risk for membership in the High (v. Remitting) trajectory.ConclusionsThe results suggest that over 30% of civilian-related injury survivors admitted to EDs experience moderate-to-high levels of PTSD symptoms within the first post-trauma year, with those reporting assaultive violence at increased risk of both immediate and longer-term symptoms.
Moral motivation and the evil-god challenge
Authors: WILSON LUKE 
Published: February 2020

AbstractThe evil-god challenge holds that theism is highly symmetrical to the evil-god hypothesis and thus it is not more reasonable to accept one rather than the other. But, since it is not reasonable to accept the evil-god hypothesis, it is not reasonable to accept theism. This article will primarily focus on defending the challenge from two recent objections which hold that it follows from the nature of moral motivation that theism is intrinsically much more likely to be true than the evil-god hypothesis. However, I will also argue that there is a different intrinsic asymmetry between the hypotheses which favours theism.
Arch intervention following stage 1 palliation in hypoplastic left heart syndrome is associated with slower feed advancement: a report from the National Pediatric Quality Cardiology Improvement Collaborative
Authors: Chaves Alicia H. , Baker-Smith Carissa M. , Rosenthal Geoffrey L. 
Published: February 2020

AbstractIntroduction:Infants undergoing stage 1 palliation for hypoplastic left heart syndrome may have post-operative feeding difficulties. Although the cause of feeding difficulties in these patients is multi-factorial, residual arch obstruction may affect gut perfusion, contributing to feeding intolerance. We hypothesised that undergoing arch reintervention following stage 1 palliation would be associated with post-operative feeding difficulties.Methods:This was a retrospective cohort study. We analysed data from the National Pediatric Cardiology Quality Improvement Collaborative, which maintains a multicentre registry for infants with hypoplastic left heart syndrome discharged home following stage 1 palliation. Patients who underwent arch reintervention (percutaneous or surgical) prior to discharge following stage 1 palliation were compared with those who underwent non-aortic arch interventions after stage 1 palliation and those who underwent no intervention. Median post-operative days to full enteral feeds and weight for age z-scores were compared. Predictors of post-operative days to full feeds were identified.Results:Among patients who underwent arch reintervention, post-operative days to full enteral feeds were greater than for those who underwent non-aortic arch interventions (25 versus 16, p = 0.003) or no intervention (median days 25 versus 12, p < 0.001). Arch intervention, multiple interventions, gestational age, and the presence of a gastrointestinal anomaly were predictors of days to full feeds.Conclusions:Repeat arch intervention is associated with a longer time to achieve full enteral feeding in patients with hypoplastic left heart syndrome after stage 1 palliation. Further investigation of this association is needed to understand the role of arch obstruction in feeding problems in these patients.
The Risk of Cancer from CT Scans and Other Sources of Low-Dose Radiation: A Critical Appraisal of Methodologic Quality
Authors: Schultz Carl H. , Fairley Romeo , Murphy Linda Suk-Ling , Doss Mohan 
Published: February 2020

AbstractIntroduction:Concern exists that radiation exposure from computerized tomography (CT) will cause thousands of malignancies. Other experts share the same perspective regarding the risk from additional sources of low-dose ionizing radiation, such as the releases from Three Mile Island (1979; Pennsylvania USA) and Fukushima (2011; Okuma, Fukushima Prefecture, Japan) nuclear power plant disasters. If this premise is false, the fear of cancer leading patients and physicians to avoid CT scans and disaster responders to initiate forced evacuations is unfounded.Study Objective:This investigation provides a quantitative evaluation of the methodologic quality of studies to determine the evidentiary strength supporting or refuting a causal relationship between low-dose radiation and cancer. It will assess the number of higher quality studies that support or question the role of low-dose radiation in oncogenesis.Methods:This investigation is a systematic, methodologic review of articles published from 1975–2017 examining cancer risk from external low-dose x-ray and gamma radiation, defined as less than 200 millisievert (mSv). Following the PRISMA guidelines, the authors performed a search of the PubMed, Cochrane, Scopus, and Web of Science databases. Methodologies of selected articles were scored using the Newcastle Ottawa Scale (NOS) and a tool identifying 11 lower quality indicators. Manuscript methodologies were ranked as higher quality if they scored no lower than seven out of nine on the NOS and contained no more than two lower quality indicators. Investigators then characterized articles as supporting or not supporting a causal relationship between low-dose radiation and cancer.Results:Investigators identified 4,382 articles for initial review. A total of 62 articles met all inclusion/exclusion criteria and were evaluated in this study. Quantitative evaluation of the manuscripts’ methodologic strengths found 25 studies met higher quality criteria while 37 studies met lower quality criteria. Of the 25 studies with higher quality methods, 21 out of 25 did not support cancer induction by low-dose radiation (P = .0003).Conclusions:A clear preponderance of articles with higher quality methods found no increased risk of cancer from low-dose radiation. The evidence suggests that exposure to multiple CT scans and other sources of low-dose radiation with a cumulative dose up to 100 mSv (approximately 10 scans), and possibly as high as 200 mSv (approximately 20 scans), does not increase cancer risk.
Exploring differences between private and public prices in the English care homes market
Authors: Allan Stephen , Gousia Katerina , Forder Julien 
Published: February 2020

AbstractThis work quantitatively assesses the potential reasons behind the difference in prices paid by care home residents in England. Evidence suggests that the price paid by private payers is higher than that paid for publicly supported residents, and this is often attributed to the market power wielded by local authorities as the dominant purchaser in local markets. Estimations of private prices at the local authority level are used to assess the difference in price paid between private and public prices, the fees gap, using data from 2008 to 2010. Controlling for local area and average care home characteristics, the results indicate that both care home and local authority market power play a role in the price determination of the market.
Particle drift potential of glyphosate plus 2,4-D choline pre-mixture formulation in a low-speed wind tunnel
Authors: Vieira Bruno C. , Butts Thomas R. , Rodrigues Andre O. , Schleier Jerome J. , Fritz Bradley K. , Kruger Greg R. 
Published: February 2020

AbstractThe introduction of 2,4-D–resistant soybean and cotton provided growers a new POST active ingredient to include in weed management programs. The technology raises concerns regarding potential 2,4-D off-target movement to sensitive vegetation, and spray droplet size is the primary management factor focused on to reduce spray particle drift. The objective of this study was to investigate the droplet size distribution, droplet velocity, and particle drift potential of glyphosate plus 2,4-D choline pre-mixture (Enlist Duo®) applications with two commonly used venturi nozzles in a low-speed wind tunnel. Applications with the TDXL11004 nozzle had larger DV0.1 (291 µm), DV0.5 (544 µm), and DV0.9 (825 µm) values compared with the AIXR11004 nozzle (250, 464, and 709 µm, respectively), and slower average droplet velocity (8.1 m s−1) compared with the AIXR11004 nozzle (9.1 m s−1). Nozzle type had no influence on drift deposition (P = 0.65), drift coverage (P = 0.84), and soybean biomass reduction (P = 0.76). Although the TDXL11004 nozzle had larger spray droplet size, the slower spray droplet velocity could have influenced the nozzle particle drift potential. As a result, both TDXL11004 and AIXR11004 nozzles had similar spray drift potential. Further studies are necessary to understand the impact of droplet velocity on drift potential at field scale and test how different tank solutions, sprayer configurations, and environmental conditions could influence the droplet size and velocity dynamics and consequent drift potential in pesticide applications.
Postoperatively increased bioactive adrenomedullin is related to	adverse outcome after complex aortic surgery
Authors: Gombert Alexander , Doukas Panagiotis , Marx Gernot , Hartmann Oliver , Bergmann Deborah , Schulte Janin , Stoppe Christian , Jacobs Michael , Simon Tim 
Published: February 2020

Summary: Background: Open and endovascular thoracoabdominal aortic aneurysm repair is related to major complications and increased mortality rates. Up to now, specific biomarkers for adverse outcome are scarce, although routine usage of such biomarkers could enable an earlier and more appropriate treatment of complications during the postoperative course after complex aortic aneurysm repair. Patients and methods: In a prospective single-center study including 33 patients (48.5 % women, mean age 63.0 ± 16.2 years) undergoing elective complex open and endovascular aortic aneurysm repair, bioactive adrenomedullin (bio-ADM) was measured for 72 h perioperatively and an association with clinical endpoints, namely cardiogenic shock, death and the combined endpoint of the two aforementioned parameters was assessed. Furthermore, the association between bio-ADM and baseline characteristics and perioperative details including sepsis biomarkers score were assessed. Results: 51.5 % (n = 17) of patients developed postoperative acute kidney injury, 21.2 % (n = 7) pneumonia and 18.2 % (n = 6) sepsis. Cardiogenic shock was observed in 12.1 % (n = 4) patients. The in-hospital mortality rate was 18.2 % (n = 6), and 24.2 % (n = 8) of patients developed cardiogenic shock and/or died in hospital. A significant correlation of bio-ADM concentrations from all available time points was observed with leukocytes (r = 0.37, P < 0.0001), C-reactive protein (r = 0.56, P < 0.001) and serum creatinine levels (r = 0.52, P < 0.001). Increased bio-ADM at 12 h, 24 h, 48 h and 72 h after admission to ICU was associated with both, in-hospital death and cardiogenic shock, with an area under the curve for the combined endpoint of 0.598, 0.720, 0.880 and 0.967. Bio-ADM concentrations at 48 h and 72 h after admission to ICU were predictive for in-hospital death and cardiogenic shock (both P < 0.01). Conclusions: Bio-ADM may serve as postoperative biomarker for cardiogenic shock and death after complex open and endovascular aortic aneurysm repair, potentially enabling an earlier and by that more adequate treatment of adverse outcome after major surgery.