bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN TINGKAT PENGETAHUAN TENTANG HIPERTENSI DENGAN SIKAP DALAM PENCEGAHAN KOMPLIKASI HIPERTENSI PADA LANSIA PESERTA PROLANIS UPT PUSKESMAS JENAWI KARANGANYAR
Authors: Harjo Mujiran Sismi , Setiyawan Setiyawan , Rizqie Noerma Shovie 
Published: July 2020

<p><strong>Latar Belakang: </strong>Hipertensi seringkali disebut sebagai pembunuh gelap (<em>silent killer</em>), dan masih menjadi masalah kesehatan pada kelompok lansia karena jika tidak terkendali akan berkembang dan menimbulkan komplikasi yang berbahaya. Angka kejadian stroke di UPT Puskesmas Jenawi tahun 2015 sebanyak 15 kasus dengan 8 kasus rawat inap. Pada tahun 2016 sebanyak 23 kasus dengan 11 kasus rawat inap dan 8 penderita stroke meninggal. Tujuan penelitian ini adalah untuk mengetahui hubungan antara tingkat pengetahuan tentang penyakit hipertensi dengan sikap pencegahan komplikasi hipertensi pada lansia peserta Prolanis UPT Puskesmas Jenawi Kabupaten Karanganyar.</p><p><strong>Metode: </strong>Metode yang digunakan dalam penelitian ini adalah observasional<em> </em>analitik dengan pendekatan <em>cross sectional study.</em> Teknik pengambilan sampel dalam penelitian ini menggunakan <em>Total sampling</em> yaitu pengambilan sampel dari seluruh populasi yang ada yakni semua lansia penderita hipertensi peserta Prolanis UPT Puskesmas Jenawi Karanganyar Cara pengumpulan data dengan menggunakan kuesioner. Teknik analisis menggunakan uji <em>Gamma.</em></p><p><strong>Hasil: </strong>Berdasarkan hasil uji <em>gamma</em> didapatkan nilai p = 0,000, karena nilai p&lt;0,05 maka Ho ditolak sehingga Ha diterima.</p><p><strong>Kesimpulan: </strong>Ada hubungan antara pengetahuan responden tentang penyakit hipertensi dengan sikap pencegahan komplikasi hipertensi pada lansia peserta prolanis pada UPT Puskesmas Jenawi Kabupaten Karanganyar. Dari uji yang sama diperoleh nilai r = 0,994 , karena nilai r termasuk dalam rentang nilai 0,8 – 1,00, maka dapat disimpulkan bahwa keduanya mempunyai hubungan yang sangat kuat.</p>
GAMBARAN KEMANDIRIAN EKONOMI PADA LANSIA
Authors: Ada' Yeremia Rante , Musfiroh Mujahidatul , Priyo Desiderius , Wiyono Vinch 
Published: July 2020

<p><strong>Latar Belakang</strong>. Kemandirian ekonomi lansia merupakan kemampuan lansia untuk memenuhi kebutuhan ekonomi lansia dengan tidak bergantung pada orang lain. Penelitian ini bertujuan untuk mengetahui karakteristik lanjut usia dan gambaran kemandirian ekonomi pada salah satu kelompok lansia di kelurahan Mojosongo.</p><p><strong>Subjek dan Metode</strong>. Penelitian ini menggunakan metode deskriptif. Jumlah sampel penelitian yaitu 56 responden lansia yang hadir pada kegiatan Posyandu Lansia di Kelurahan Mojosongo Kota Surakart. Sampel dalam penelitian ini diperoleh dengan menggunakan teknik random sampling. Teknik pengumpulan data menggunakan teknik wawancara, observasi, dokumentasi, catatan lapangan, dan kepustakaan.</p><p><strong>Hasil Penelitian</strong>. Hasil penelitian menunjukkan bahwa 61% responden berusia sekitar 56-65 tahun, 55% responden berjenis kelamin perempuan, 75% responden masih aktif bekerja, 75% responden memiliki penghasilan &lt; Rp 1.802.700, 50% responden memiliki pengeluaran setiap bulan berkisar Rp 1.000.000-1.500.000 dengan jenis pengeluaran terbesar (84%) untuk memenuhi kebutuhan akan makanan dan kebutuhan lainnya seperti listik, air dan Rukun Tetangga, 77% responden tidak memiliki usaha dan 52% tidak memiliki jenis keterampilan tertentu.</p><p><strong>Simpulan</strong>. Gambaran ekonomi responden sudah baik. Banyak responden yang masih bekerja. Namun penghasilan yang diperoleh masih dibawah Upah Minimal Regional (UMR). Upaya pemenuhan kebutuhan ekonomi lansia tidak didukung dengan kepemilikan usaha dan ketrampilan lansia. Sehingga responden hanya bergantung pada pekerjaan yang upahnya masih dibawah UMR.</p>
HUBUNGAN POLA PEMBERIAN MAKANAN PENDAMPING ASI DENGAN BERAT BADAN BAYI USIA 6-12 BULAN DI KELURAHAN WONOREJO KABUPATEN KARANGANYAR
Authors: Hardiningsih Hardiningsih , Anggarini Sri , Yunita Fresthy Astrika , Yuneta Agus Eka Nurma , Kartikasari Nur Dewi , Ropitasari Ropitasari 
Published: July 2020

<p><strong>Latar Belakang:</strong> Pola pemberian makanan sangat mempengaruhi pertumbuhan berat badan bayi. ASI saja tidak bisa memenuhi semua kebutuhan energi dan zat gizinya, karena pemenuhan gizi bayi dari ASI hanya sebesar 65 – 80 %. Pola pemberian makanan pada bayi sangat berhubungan dengan berat badan bayi, karena pola tersebut memberikan gambaran frekuensi pemberian makan, jenis/ bentuk makanan maupun jumlah takaran yang diberikan. Tujuan penelitian ini yaitu<strong> </strong>enganalisis hubungan pola pemberian makanan pendamping ASI dengan berat badan bayi usia 6-12 bulan.</p><p><strong>Metode </strong><strong>penelitian:</strong> Desain penelitian adalah <em>cross sectional</em>. Penelitian dilakukan di posyandu kelurahan Wonorejo Kabupaten Karanganyar. Populasi yang digunakan dalam penelitian ini adalah ibu yang mempunyai bayi berusia 6-12 bulan di posyandu kelurahan Wonorejo. Teknik <em>cluster random sampling</em>. Alat ukur kuesioner, lembar wawancara, timbangan bayi dan KMS. Analisis data dengan uji statistik <em>Chi Square</em>.</p><p><strong>Hasil penelitian:</strong> Mayoritas responden yang diteliti memberikan MP-ASI secara tepat, baik dalam hal bentuk MP-ASI (65%), frekuensi pemberian (72.2%), dan jumlah takaran (70%). Pada variabel berat badan yaitu mayoritas berat badan bayi meningkat (17.5%). Selanjutnya, terdapat hubungan bentuk MP-ASI terhadap berat badan (OR= 18.75; p=0.02); terdapat hubungan frekuensi pemberian MP-ASI terhadap berat badan (OR= 11.25; p=0.04); serta terdapat hubungan jumlah takaran MP-ASI<em> </em>terhadap berat badan (OR= 27; p&lt;0.001).</p><p><strong>Kesimpulan:</strong> Pada penelitian ini, mayoritas responden yang diteliti telah memberikan MP-ASI sesuai pola yang dianjurkan. Pada variabel berat badan yaitu mayoritas berat badan bayi meningkat. Selanjutnya, terdapat hubungan bentuk, frekuensi, serta jumlah takaran MP-ASI terhadap berat badan.</p>
ВОЗМОЖНОСТИ ЭТИОТРОПНОЙ ТЕРАПИИ КОРОНАВИРУСНОЙ ИНФЕКЦИИ, ВЫЗВАННОЙ SARS-COV-2, У АМБУЛАТОРНЫХ ПАЦИЕНТОВ
Authors: Руженцова Татьяна 
Published: July 2020

В статье представлены промежуточные результаты клинического исследования эффективности и безопасности этиотропной терапии у амбулаторных пациентов с новой коронавирусной инфекцией, вызванной вирусом SARS-CoV-2.
Цель исследования: изучить эффективность и безопасность применения препарата фавипиравира у больных новой коронавирусной инфекцией (COVID-19) в амбулаторной практике в сравнении с рекомендованной стандартной терапией.
Материалы и методы. В исследование включали мужчин и женщин с заболеванием COVID-19 в возрасте от 18 до 60 лет. Основную группу составили пациенты, получавшие лечение препаратом фавипиравира, в группе сравнения пациентам назначалась этиотропная терапия в соответствии с актуальной версией Временных методических рекомендаций Минздрава России «Профилактика, диагностика и лечение коронавирусной инфекции (COVID-19)». Из 60 рандомизированных пациентов: 40 пациентов получали лечение фавипиравиром и 20 пациентов - терапию сравнения.
Эффективность и безопасность терапии определяли на основании оценки клинического улучшения по Порядковой шкале клинического улучшения ВОЗ, клинико-лабораторных данных, результатов компьютерной томографии органов грудной клетки и показателей элиминации вируса SARS-CoV-2.
Результаты. Проведенный сравнительный анализ эффективности показал, что клиническое улучшение по Порядковой шкале клинического улучшения ВОЗ, соответствующее положительной динамике или разрешению клинической симптоматики, в основной группе наступало, в среднем, на 6,95±4,55 день, в группе сравнения - на 10,4±5,0 день, (р<0,05). На 7-й день исследования клиническое улучшение отмечалось у 55% пациентов, получавших терапию фавипиравиром, в группе сравнения улучшение отмечено у 20%. Элиминация коронавируса SARS-CoV-2 на 3-и сутки этиотропной терапии достигалась у 65% пациентов группы фавипиравира и у 55% пациентов группы сравнения. На фоне приёма фавипиравира не было зарегистрировано случаев госпитализации амбулаторных пациентов, тогда как в группе сравнения 10% пациентов были госпитализированы в связи с нарастанием тяжести течения заболевания. Серьезных нежелательных явлений зарегистрировано не было.
Выводы. Применение фавипиравира для лечения инфекции, вызванной коронавирусом SARS-CoV-2, позволяет сократить период до наступления клинического улучшения, в среднем, на 3,45 дня. У амбулаторных пациентов с COVID-19 на фоне противовирусной терапии элиминация вируса достигается, в большинстве случаев, на 3-и сутки. Профиль безопасности фавипиравира соответствует описанному в литературных источниках. Общая частота нежелательных явлений в группе, получавшей фавипиравир, сопоставима с показателями на фоне стандартной терапии.
Rasio Keuangan dan Return Saham Syariah
Authors: Widyarini Dyah Putri , Ridha Muhammad Arsyadi 
Published: July 2020

This study investigates the effect of financial ratios on stock returns at companies listed in Indeks Saham Syariah Indonesia (ISSI) period 2012-2016. This study uses quantitative methods with secondary data collected from the company's financial statements. The population in this study were all companies listed on the Syariah Indonesia Stock Index (ISSI) during the period of 2012-2016 as many as 149 companies. Based on the sampling technique with purposive sampling method obtained a sample of 59 companies with data collected during the period 2012-2016 as many as 295 financial report data. In this study panel panel regression was used to see the effect of the independent variables consisting of ROCE, TATO, TIER, PER and CFR on the dependent variable namely Stock Return. Processing data in this study using Eviews 9. Software. Data analysis techniques in this study using statistical techniques with the help of Eviews 9 program. Based on 59 companies observed, fixed effect panel data regression models have been used to examine the relevance to the effect of financial ratios on stock returns. The result of the research, found that the Total Asset Turnover (TATO) and Time Interest Income Ratio (TIER) have a positive effect on stock returns. Total Asset Turnover (TATO) and Time Interest Earned Ratio (TIER) can be considered by investors to make decisions in choosing which companies have high stock returns. Return On Capital Employed (ROCE), Price To Earning Ratio (PER), and Cash Flow Ratio (CFR) are not related to stock returns.
Analisis Perbandingan Pola Konsumsi Masyarakat Kota Jambi Sebelum, Sesaat dan Sesudah Bulan Ramadhan
Authors: Habriyanto Habriyanto 
Published: July 2020

This study aims to see the level of comparison of the consumption patterns of Jambi netizen before, during and after the month of Ramadan. The research approach uses descriptive qualitative analysis method of data triangulation consisting of interview data, observations and questionnaires by comparing consumption expenditure financing. This study used 140 respondents with the findings that 95% of respondents said they had increased consumption costs in the month of Ramadan. The comparison of Jambi Netizen’s consumption level before, when and after Ramadhan measured by the level of food and drink, clothing expenditure. Expenditure ini Ramadan month has increased from 41% -50% and 91% -100% compared to other months, while the clothing’s expenditure in the Ramadan month compared to other months has increased by the ranges from 150% -249% and 250% -349%. The differences in consumption patterns in ramadhan month compared to other months can be seen in the increasing number of people who shop in the market for on one day before ramadhan to prepare consumption needs in the month of Ramadan and H-10 during Ramadan to prepare for buying Lebaran clothes and consumption of Eid preparations. At the time of Ramadan there is a tradition of going home, on average, the respondents claim spent accommodation funds ranging from Rp. 1,000,000 to Rp. 2,500,000 and also adjusted to the distance to the hometown plus the purchase of consumption and souvenirs for the family in the hometown.
The Determinants of Islamic Banking Capital Structure in Indonesia
Authors: Fauziah Fenty , Latief Azhar , Jamal Sri Wahyuni 
Published: July 2020

This study aims to analyze and explain the factors that influence capital structure. Capital structure (CS) is measured by Debt to Equity Ratio (DER). Profitability is determined by Return on Assets (ROA) and Net Profit Margin (NPM). Loan to Deposit Ratio (LDR) is used as an indicator of risThis study aims to analyze and explain the factors that influence capital structure. Capital structure (CS) is measured by the Debt to Equity Ratio (DER). Profitability is determined by Return on Assets (ROA) and Net Profit Margin (NPM). Financial to Deposit Ratio (FDR) is used as an indicator of risk. Firm size is projected with Ln TA. The population of this study is all Islamic banks contained in Bank Indonesia, with observation periods starting in 2010 until 2018. The selection of samples in this study is a purposive sampling method. Data analysis and hypothesis testing were carried out by using the Eviews 11 program. The results of the study showed that sharia banking companies, all the independent variables simultaneously had a significant effect on the capital structure. Return on Assets (ROA) and firm size have affected the capital structure. Islamic bank managers in Indonesia choose the capital structure obtained from internal funds and the larger the company, it is necessary to arrange capital structure, to obtain the sustainability of the company in the future.k. Firm size is projected with Ln TA. The population of this research is all Islamic banks contained in Bank Indonesia, with observation periods starting in 2010 until 2017. The selection of samples in this study is purposive sampling method. Data analysis and hypothesis testing were carried out by structural equation model approach using the SPSS program. The results of the study showed that in Islamic sharia companies, all the independent variables simultaneously had a significant effect on the capital structure, partially only the Loan to Deposit Ratio (LDR) variable that did not affect the capital structure, while the other independent variables had a significant temporary effect on conventional Research conducted by the researchers themselves used some of the same variables and using the PLS 3.0 analysis tool there were similar results that only risks did not affect the capital structure. The conclusion of this study is that there is no difference in capital structure in Islamic banking companies and conventional banking companies.
Kompetensi Sosial Guru Pendidikan Agama Islam dalam Meningkatkan Prestasi Siswa
Authors: Parnawi Afi 
Published: July 2020

As a proffesional person in the field of education, teacher has some roles, such as: being a teacher, mentor, class adminisrator, curriculum developer, profiessionla developer, and public relation. A competence, in the perspective of education, is a necessity, since it must be based on the mastery of a knowledge. The teacher’s social competence should be the tools of communcation and interaction to the students, fellow educators, educational officers, students’ parents, and the society. Education has an important role in improving the quality of human resources and as an efforts to realize the public welfare of the intelectual life of the nation. Taken from the decree of Indonesian government, it is stated that “Education is implemented to develop the capabilities and to shape the dignified national character aiming to develop the potetentials of Indonesian people to be faithful and devoted to Allah and to create the noble, healthy, knowledgable, capable, crative, and independent person as well as to become a democratic and responsible citizen.
Risk Factors of Metachronous Brain Metastasis in Patients with EGFR-Mutated Advanced Non-Small Cell Lung Cancer
Authors: Ouyang Wen , Yu Jing , Zhou Yan , Hu Jing , Huang Zhao , Zhang Junhong , Xie Conghua 
Published: July 2020

Abstract
Background NSCLC patients with EGFR mutation were at a higher incidence of developing brain metastasis (BM). Patients with BM are associated with high mortality. Reducing BM incidence becomes increasingly significant for NSCLC patients to achieve prolonged survival. The aim of the study was to explore the possible risk factors of developing metachronous BM during EGFR-TKIs treatment, and to identify the potential candidates for prophylactic cranial irradiation (PCI ) or the first-line osimertinib treatment. Methods A total of 157 consecutive EGFR-mutated advanced NSCLC patients without BM at initial diagnosis in our institution from 2012 and 2018 were retrospectively reviewed . Comparisons of OS were performed based on BM status. The cumulative incidence of metachronous BM was calculated by the Kaplan-Meier method, and the independent risk factors of metachronous BM were investigated by multivariate analysis. Results Patients developing metachronous BM had worse survival (mOS: 22.1 months) than patients not-developing BM (mOS: 44.8 months). Moreover, the multivariate analysis indicated that age ≤ 49 years ( P =0.035), number of extracranial metastases ( P =0.013), and malignant pleural effusion ( P =0.002) were independent risk factors of metachronous BM. Furthermore, the 1-year actuarial incidence of developing metachronous BM in patients with no risk factor (n =101), 1 risk factor (n =46), and 2 risk factors (n =10) were 7.01%, 14.61%, and 43.75%, respectively ( P <0.001). Conclusions Patients developing metachronous BM during EGFR-TKIs treatment have worse outcomes. Our results suggested that EGFR-mutated advanced NSCLC patients with ≥ 1 risk factors were candidates for PCI or the first-line Osimertinib treatment.
Three protein extraction methods for mass spectrometry proteomics of fresh frozen mouse tissue
Authors: Ser Zheng , Kentsis Alex 
Published: July 2020

Abstract
Human and animal tissues are frequently fresh frozen for archival storage. These specimens can be used for proteomic analysis to analyze proteome composition. A critical step in these proteomic analyses is the extraction of proteins from fresh frozen samples, which can affect the sampling of the proteomes. Here, we compare three different methods for protein extraction from fresh frozen mouse heart tissue: 1) extraction using SDS buffer followed by FASP purification, 2) extraction using SDS buffer followed by S-Trap purification, and 3) extraction using a guanidine hydrochloride buffer followed by in-solution digestion. Based on bicinchoninic acid assay, all three methods display similar recovery of total protein content. However, proteomics-based analysis identified far fewer proteins from the extraction guanidine hydrochloride. SDS-FASP identifies as many proteins as the SDS-STrap method with good coverage of proteins from different cellular compartments.
Modified pedicle screw-rod versus anterior subcutaneous internal pelvic fixation for unstable pelvic anterior ring fracture: A retrospective study and finite element analysis
Authors: Ding Sheng-Long , Chen Fan-Cheng , Huang Jun-Ming , Zhang Guang-Ming , Wang Fu-Yong , Lei Jing-Hui , Wu Xiao-Tian , Ruan Zhi-yong 
Published: July 2020

Abstract
Objectives: This study compared the stability and clinical outcomes of modified pedicle screw-rod fixation (MPSRF) and anterior subcutaneous internal pelvic fixation (INFIX) for the treatment of anterior pelvic ring fractures using Tornetta and Matta grading system and finite element analyses.Methods: In a retrospective review of a consecutive patient series, 63 patients with Orthopaedic Trauma Association (OTA)/Arbeitsgemeinschaft für Osteosynthesefragen (AO) type B or C pelvic ring fractures were treated by MPRSF (n=30) or INFIX (n=33). The main outcome measure were Majeed score, incidence of complications and adverse outcomes, and fixation stability was evaluated by finite element analysis (FEA).Results: two groups did not differ in terms of injury severity score, OTA classification, cause of injury, and time to pelvic surgery. However, the MPSRF group had a higher satisfactory rate according to the Tornetta and Matta grading system than the INFIX group (73.33% vs 63.63%) as well as a higher Majeed score (81.5±10.4 vs 76.3±11.2), which was statistically significant at 6 months’ post-surgery. FEA showed that MPRSF was stiffer and more stable than INFIX and had a lower risk of implant failure.Conclusions: Both MPSRF and INFIX have acceptable biomechanical stability for the treatment of unstable pelvic anterior ring fractures. However, MPRSF has better fixation stability and lower risk of implant failure, which can lead to better clinical outcomes.
Beauveria bassiana ERL836 and JEF-007 with similar virulence show different gene expression when infecting western flower thrips, Frankniella occidentalis
Authors: Kim Sihyeon , Kim Jong Cheol , Lee Se Jin , Lee Mi rong , Park So Eun , Li Dongwei , Baek Sehyeon , Shin Tae Young , Kim Jae Su 
Published: July 2020

Abstract
Background: Insect-killing fungal species, Beauveria bassiana, is as an environment-friendly pest management tool, and many isolates are on the track of industrialization. However, some of B. bassiana isolates show similar morphology and virulence against insect pests, and so it is hard to differentiate them. Herein we used two patented isolates, ERL836 and JEF-007, and investigated their virulence against western flower thrips, Frankliniella occidentalis, and further analyzed genome structures and transcriptional responses when infecting the thrips to see possible differences.

Results: The two isolates showed no significant differences in fungal growth, conidial production, and virulence against thrips, and they were structurally similar in genome. But, in transcription level, ERL836 appeared to infect thrips easily, while JEF-007 appeared to have more difficulty. In the GO analysis of ERL836 DEGs (differentially expressed genes), the number of up-regulated genes was much larger than that of down-regulated genes, when compared to JEF-007 DEGs (more genes down-regulated). Interestingly, in the enrichment analysis using shared DEGs between two infecting isolates, plasma membrane-mediated transporter activity and fatty acid degradation pathway including cytochrome P450 were more active in infecting ERL836.

Conclusion: The two B. bassiana isolates had similar morphology and virulence as well as genome structure, but in transcription level they differently infected western flower thrips. This comparative approach using shared DEG analysis could be easily applied to characterize the difference of the two B. bassiana isolates, JEF-007 and ERL836.