bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between supportive attitudes and adoptive practice of control strategy against COVID-19 among college students in China, a cross-sectional study
Authors: Shen Dong , Liu Dan , Cai Miaochun , Chen Peiliang , Wang Zhenghe , Zhang Yujie , Li Zhihao , Zhang Xiru , Wu Xianbo , Yang Xingfen , Mao Chen 
Published: August 2020

Abstract
Background: This study aimed to explore college students’ attitudes and compliance toward the prevention strategy of using non-pharmaceutical interventions (NPIs) in containing coronavirus disease 2019. Methods: We conducted a cross-sectional online survey in four universities in Guangdong Province (China) based on purposive sampling. We used a self-made questionnaire to measure the supportive attitude towards outbreak control strategy and adoption of NPIs in respondents. Results: A total of 44,446 college students participated between 31 January and 10 February 2020; 92.7% of respondents supported the outbreak control strategy. 94.8% would avoid public places, 92.8% would wear a facemask, 91.2% would avoid of gatherings and 86.9% would wash hands more frequent. 76.5% respondents adopted all four measures. Supportive attitude was associated with NPI adoption. Students who were female, postgraduate, anxious, and not depressed tended to have higher supportive attitude and higher NPI adoption rate. Conclusions: Higher supportiveness towards the disease control strategy for public may lead to higher adoption rate of NPIs for individuals. Psychosocial factors are related to supportive attitude and adoption of the NPIs. We believe that our findings are instructive about the prevention and control of emerging infectious diseases like COVID-19.
Wireless Battery Free Fully Implantable Multimodal Recording and Neuromodulation Tools for Songbirds
Authors: Ausra Jokubas , Munger Stephanie , Azami Amirhossein , Burton Alex , Peralta Roberto , Miller Julie , Gutruf Philipp 
Published: August 2020

Abstract
Wireless battery free and fully implantable tools for the interrogation of the central and peripheral nervous system have quantitively expanded the capabilities to study mechanistic and circuit level behavior in freely moving rodents. The light weight and small footprint of such devices enables fully subdermal implantation that results in the capability to perform studies with minimal impact on subject behavior and yields broad application in a range of experimental paradigms. While these advantages have been successfully proven in rodents that move predominantly in 2D the full potential of a wireless and battery free device can be harnessed with species that move in 3D, where interrogation with tethered devices is very difficult or impossible. Here we report on a wireless, battery free and multimodal platform that enables optogenetic stimulation and physiological recording in a highly miniaturized form factor for use in songbirds. The systems are enabled by behavior guided primary antenna design and advanced energy management to ensure stable optogenetic stimulation and physiological recording throughout 3D experimental arenas. Collectively, these design approaches quantitatively expand the use of wireless subdermally implantable neuromodulation and sensing tools to species previously excluded from in vivo real time experiments.
Comparison of Full-Endoscopic Visualized Unilateral Laminotomy Bilateral Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion for One-Level Lumbar Spinal Stenosis
Authors: Hua Wenbin , Wang Bingjin , Ke Wencan , Wu Xinghuo , Zhang Yukun , Li Shuai , Yang Shuhua , Yang Cao 
Published: August 2020

Abstract
Background: The aim of the present study is to compare the clinical outcomes and postoperative complications of full-endoscopic visualized unilateral laminotomy bilateral decompression (FEV-ULBD) and minimally invasive surgery-transforaminal lumbar interbody fusion (MIS-TLIF) to treat one-level lumbar spinal stenosis (LSS) without degenerative spondylolisthesis or deformity. Methods: A retrospective analysis of 112 consecutive patients of one-level LSS undergoing either FEV-ULBD or MIS-TLIF was performed. Patient demographics, operation time, estimated blood loss, time to ambulation, length of hospitalization, intraoperative and postoperative complications were recorded. The visual analog scale (VAS) score for leg and back pain, the Oswestry Disability Index (ODI) score, and the Macnab criteria were used to evaluate the clinical outcomes. The healthcare cost was also recorded.Results: The operation time, estimated blood loss, time to ambulation and length of hospitalization of FEV-ULBD group were shorter than MIS-TLIF group. The postoperative mean VAS and ODI scores decreased significantly in both groups. According to the modified Macnab criteria, the outcomes rated as excellent/good rate were 90.6% and 93.8% in the two groups. The mean VAS scores, ODI scores and outcomes of the modified Macnab criteria of both groups were of no significant difference. The healthcare cost of FEV-ULBD group was lower than MIS-TLIF group. Two cases of intraoperative epineurium injury were observed in the FEV-ULBD group. One case of cauda equina injury was observed in the FEV-ULBD group. No nerve injury, dural injury or cauda equina syndrome was observed in MIS-TLIF group. However, one case with transient urinary retention, one case with pleural effusion, one case with incision infection and one case with implant dislodgement were observed in MIS-TLIF group. Conclusions: Both FEV-ULBD and MIS-TLIF are safe and effective to treat one-level LSS without degenerative spondylolisthesis or deformity. FEV-ULBD is a more minimally invasive option and of less economic burden compared with MIS-TLIF. Decompression plus instrumented fusion may be not necessary for one-level LSS without degenerative spondylolisthesis or deformity.
Symmetrical Dental Occlusion Blocking - What are the Required Changes of Pressure Distribution to be Clinical Relevant?
Authors: Maurer-Grubinger C , Avaniadi Ioanna , Adjami Frederic , Christian Wolfgang , Doerry Charlotte , Fay Viola , Fisch Vanessa , Gerez Ali , Goecke Julian , Kaya Ugur , Keller Julia , Krüger Dominik , Pflaum Jukia , Porsch Laurin , Wischnewski Christina , Scharnweber Benjamin , Sosnov Polyna , Oremek Gerhard , Groneberg David A. , Ohlendorf Daniela 
Published: August 2020

Abstract
Background: Symmetrical dental occlusion blocking (bicuspid region) is used in dentistry as a quick diagnostic test (“Meersseman test”) to check a possible influence of the temporomandibular system (TMS) on the movement system. Immediate effects between occlusal blocking and rest position on body sway and weight distribution in general and for both genders and for four age decades should be evaluated.Methods: 725 (396f/329m) healthy subjects (neither subjective signs of TMD nor acute/chronic complaints in the musculoskeletal system) volunteered (21 to 60 years) while both genders were divided into four age groups according to decades. A pressure measuring platform was used. The postural control (body sway and weight distribution) was recorded in two dental occlusion conditions (a) in rest position and (b) symmetrical blocking (bicuspid region) by cotton rolls. Results: The frontal sway reduced by 0.67mm (t(724) = -3.9 (p < 0.001)) and the sagittal sway by 0.33mm (t(724) = -3.4 (p < 0.001)). The relative pressure under the forefoot left increased by 0.33% (t(724) = 2.88 (p < 0.001)) and the relative pressure overall under the forefoot increased by 0.67% (t(724) = -3.4 (p < 0.001)). Gender-specific and age-specific reactions cannot be recorded.Discussion: In all subjects the postural sway improved slightly when blocking the occlusion ("Meersseman test") compared to the rest position. There is a slight shift of weight on the forefoot, especially the left forefoot. There exist no age- and gender-specific differences. Clinically relevant differences should apply outside the data between the 1st and 3rd quantile.
Spatial Distribution and Factors Associated with Risky Health Behaviour Among Adult Males Aged 15-59 Years in Ethiopia; Generalized Structural Equation Modelling
Authors: Kebede Sewnet Adem , Weldesenbet Adisu Birhanu , Tusa Biruk Shalmeno 
Published: August 2020

Abstract
Background: Alcohol drinking and tobacco smoking are the largest preventable cause of death and important risk factors for a number of non-communicable diseases and cause premature death and many socioeconomic consequences. Therefore, the present study aimed to assess the spatial distribution of risky health behaviour and its associated factors among adult males in Ethiopia. Methods: Secondary data analysis was conducted among 12,688 men (aged 15–59 years). The distribution of risky health behaviour across the country was observed by ArcGIS software. In SaTScan software, the Bernoulli model was fitted by Kulldorff methods to identify the purely spatial clusters of risky health behaviour. Generalized Structural Equation Model (GSEM) was used to determine factors associated with each domain of risky health behaviour (regular alcohol drinking and tobacco smoking).Results: Risky health behaviour had spatial variation across the country. The primary clusters were located in Tigray, Amhara and north-eastern Benishangul national regional states. Spatial scan statistics identified 118 primary clusters (Log-Likelihood ratio (LLR) =524.8, p < 0.001). Residence, frequency of listening to a radio, occupation and frequency of watching television were significantly associated with drinking alcohol whereas wealth index was associated with tobacco smoking. Age, region, educational status, marital status and religion had association with both domains of risky health behaviour.Conclusion: Risky health behaviour had spatial variation across the country. The national press media in ban of advertising and promotion of alcohol and tobacco should be strengthen. Aggressive health education efforts should be directed toward this high-risk population (Tigray, Amhara and north-eastern Benishangul regional states). Improving risky health behaviour is an important approach to reducing health disparities and for more cost-effective utilization of scarce resources in the public health sector.
Limiting potential COVID-19 contagion in squatting public toilets
Authors: Han Jia , Pan Li , Chen Shuang-lan , Guo Yi-sha , Du Yu-xiang , Wu Xiao-di , Jones Alice YM 
Published: August 2020

Abstract
Background: Since the outbreak of the SARS-CoV-2 virus in December 2019, the COVID-19 pandemic continues to threaten global stability. Transmission of SARS-CoV-2 is mostly by respiratory droplets and direct contact but viral RNA fragments have also been detected in the faecal waste of patients with COVID-19. Cleanliness and effective sanitation of public toilets is a concern, as flushing the toilet is potentially an aerosol generating procedure. When the toilets are of the squatting type and without a cover, there exists a risk of viral contamination through the splashing of toilet water and aerosol generation. Methods: This study reports an online survey of 134 people in China to determine whether the cleanliness of public toilets was a concern to the general population during the COVID-19 pandemic, and whether a squatting toilet was preferred to a seated design.Results: The survey showed that 91% of participants preferred squatting toilets, but that 72% were apprehensive of personal contamination when using public toilets. Over 63% of the respondents had encountered an incidence of water splash and would prefer public toilets to be covered during flushing and 83% of these respondents preferred a foot-controlled device.Conclusions: This survey suggests that consideration should be given to the installation of a simple foot-controlled device to cover public squatting toilets to help restrict potential COVID-19 contamination and to meet hygienic expectations of the public.
Impact of Delirium on Short-term Prognosis in Geriatric Patients with Hip Fracture
Authors: An Shuai , Wu Jingwei , Feng Mingli , Li Zheng , Li Zonghan , Cheng Jingbo , Cao Guanglei , Liu Limin , Lu Shibao 
Published: August 2020

Abstract
Background: To explore the effect of delirium on postoperative early prognosis of geriatric patients with hip fracture. Methods: According to whether postoperative delirium (POD) appeared in elderly patients with hip fracture, all cases were divided into two groups: delirium and non-delirium. General parameters, operative parameters, length of stay (LOS), and perioperative complications were recorded. Recurrent fracture, new stroke, and mortality within 1 year postoperatively were followed up and compared between the two groups. Results: Of 358 cases, 55 (15.4%) developed delirium. Compared with the non-delirium group, the delirium group had longer operative times (P=0.031); increased platelet (P=0.002) and C-reactive protein (P<0.001) levels; and reduced hemoglobin (P<0.001), calcium (P=0.040), albumin (P<0.001), prealbumin (P<0.001), and total cholesterol (P=0.019) levels. Complications occurred to some extent in 196 cases (54.7%). In the delirium group, complication rates of pulmonary infection (P=0.005), hypoalbuminemia (P<0.001), electrolyte disorder (P<0.001), dyspepsia (P=0.027), bedsore (P=0.012) and anemia (P=0.007) were higher. In addition, LOS was significantly longer (15.71 ± 4.72 vs 14.00 ± 5.30 days; P=0.026) in the delirium group. Within 1 year postoperatively, 31 individuals (8.7%) had died, 13 were treated for recurrent fracture, and 42 had a new stroke. In the delirium group, mortality within 1 year postoperatively was higher (27.3% vs 5.3%, P<0.001). Conclusions: The morbidity of POD is high in geriatric patients with hip fractures. There was longer surgery delay, higher complication rate, longer LOS, and increased mortality in the delirium group. Early intervention of POD has important clinical significance.
Community Stakeholder Preferences for Evidence-Based Practice Implementation Strategies in Behavioral Health: A Best-Worst Scaling Choice Experiment
Authors: Williams Nathaniel , Candon Molly , Stewart Rebecca , Byeon Y. Vivian , Bewtra Meenakshi , Buttenheim Alison , Zentgraf Kelly , Comeau Carrie , Shoyinka Sosunmolu , Beidas Rinad S. 
Published: August 2020

Abstract
Background: Community behavioral health clinicians, supervisors, and administrators play an essential role in implementing new psychosocial evidence-based practices (EBP) for patients receiving psychiatric care; however, little is known about these stakeholders’ values and preferences for implementation strategies that support EBP use, nor how best to elicit, quantify, or segment their preferences. This study sought to quantify clinician, supervisor, and administrator preferences for implementation strategies and to identify segments of these stakeholders with distinct preferences using a rigorous choice experiment method called best-worst scaling (BWS). Methods: A total of 240 clinicians, 74 clinical supervisors, and 29 administrators delivering publicly funded behavioral health services in a large metropolitan behavioral health system participated in a best-worst scaling choice experiment. Participants evaluated 14 implementation strategies developed through extensive elicitation and pilot work within the target system. Preference weights were generated for each strategy using hierarchical Bayesian estimation. Latent class analysis identified segments of stakeholders with unique preference profiles. Results: On average, clinicians, supervisors, and administrators preferred two strategies significantly more than all others—compensation for use of EBP per session and compensation for preparation time to use the EBP; two strategies were preferred significantly less than all others—performance feedback via email and performance feedback via leaderboard. However, latent class analysis identified four distinct segments of stakeholders with unique preferences: Segment 1 (n = 121, 35%) strongly preferred financial incentives over all other approaches; Segment 2 (n = 80, 23%) preferred technology-based strategies; Segment 3 (n = 52, 15%) preferred an improved waiting room to enhance client readiness and strongly disliked any type of clinical consultation; Segment 4 (n = 90, 26%) rejected financial incentives and strongly preferred strategies focused on clinical consultation. Conclusions: The presence of four heterogeneous subpopulations within this large group of behavioral health administrators, supervisors, and clinicians suggests optimal implementation may be achieved through targeted strategies derived via elicitation of stakeholder preferences. Best-worst scaling is a feasible, systematic, and rigorous method for eliciting stakeholders’ implementation preferences and identifying subpopulations with unique preferences in behavioral health settings.
The Anti Swing Strategy of Davit System to Unmanned Surface Vehicle at Sea
Authors: Wei Shao-Liang , Wang Haoqi , Feng Zhen-Wei , Zhang Shuai , Cheng Feng-Yu 
Published: August 2020

Abstract
Aiming at the problem that the marine mother ship's davit system cannot accurately and quickly hoist due to wind and waves during the process of recovering the unmanned boat, an anti-swaying gondolas recovery system is designed to realize the automatic hoisting and deployment of the unmanned boat for recovery or deployment. We created a tension-length gondola recovery and deployment system model, which reduced the swing angle of the unmanned boat davit system's hoisting and deployment through adaptive control of the tension and length of the davit ropes, thereby realizing the installation and deployment of unmanned maritime boats at sea. It’s accurate and fast. Simulation experiments show that under the combined action conditions of 10 ° roll angle and 5 ° pitch angle, the deflection range of the gondola system equipped with a deflection device can reach about 60%.
Association of the SLC6A4, SLC6A3, COMT and BDNF Gene Polymorphisms with Suicidal Behavior: A Case Control Study
Authors: Rafikova Ekaterina , Shadrina Maria I. , Slominsky Peter A. , Guekht Alla B. , Ryskov Aleksei P. , Shibalev Dmitry V. , Vasilyev Vasiliy A. 
Published: August 2020

Abstract
BackgroundSuicide causes about 1 million deaths per year. Familial transmission of suicide, as well as the involvement of serotonin and dopamine systems in suicidal behavior, was confirmed by previous studies. We investigated an effect of 11 polymorphisms of 9 genes related to dopamine and serotonin transmission (SLC6A4, HTR1A, HTR2A, HTR1B, SLC6A3, DRD4, DRD2, COMT, and BDNF) on the risk of suicide. MethodsThe study was performed on 100 psychiatric clinic patients with repeated suicide attempts. Genomic DNA was obtained from venous blood. Genotyping was performed using locus-specific PCR. Statistical analysis was carried out using a Pearson Chi-squared test, ORs, with the corresponding 95% CIs and one-way ANOVA.ResultsAssociation of the SLC6A3 40–45 bp VNTR and SLC6A4 rs25531 loci with suicidal behavior was tested for the first time. We have shown that a short allele of SLC6A3 40–45 bp VNTR locus might increase the risk of suicidal attempts (p = 0.009). Contrary to previous research, we have found that the Val-allele of COMT rs4680 is associated with suicide (p = 0.028). T-allele of BDNF rs6264 and A-allele of SLC6A4 rs25531 were associated with suicidal behavior with p = 0.029 and p = 0.047, respectively. ANOVA showed the lack of association between these loci and severity of depressive symptoms, but revealed a possible effect of SLC6A4 40 bp VNTR and HTR1B loci on anxiety symptoms. ConclusionsOur results suggest that allelic variants of SLC6A3, SLC6A4, COMT and BDNF genes might be considered as risk factors for repeated suicide attempts in patients with different mental disorders. Loci SLC6A4 40 bp VNTR and HTR1B rs6296 may affect anxiety symptoms.
The Attenuation of Insulin-Like Growth Factor Signaling May Be Responsible for Relative Reduction in Matrix Synthesis in Degenerated Areas of Osteoarthritc Cartilage
Authors: Tanaka Nobuho , Tsuno Hirotaka , Ohashi Satoru , Iwasawa Mitsuyasu , Furukawa Hiroshi , Kato Tomohiro , Fukui Naoshi 
Published: August 2020

Abstract
Background: In osteoarthritis (OA), cartilage matrix is lost gradually despite enhanced matrix synthesis by chondrocytes. This paradox may be explained, at least partly, by reduced chondrocyte anabolism in degenerated area of OA cartilage. However, to date, it is not known why chondrocyte anabolism is suppressed in those areas. Methods: Cartilage was obtained from control knees and end-stage OA knees in macroscopically preserved areas and degenerated areas, and gene expression was analyzed in respective regions of cartilage using laser capture microdissection and qPCR. For the cartilage protein analysis, cartilage was obtained from preserved areas and degenerated areas of OA knees in pairs, and proteins were extracted using urea buffer. Protein concentrations were determined by Luminex and compared between the areas. Cartilage explants prepared from preserved areas and degenerated areas of OA knees were cultured in the presence or absence of an AKT inhibitor, and the gene expression was evaluated by qPCR. Finally, the expression of SP1 was evaluated in OA and control cartilage, and the significance of Sp1 on the expression of IGF1R and IRS1 was investigated in experiments using primary cultured chondrocytes.Results: Within OA cartilage, the expression of IGF-1, IGF-2, IGF1R and IRS1 was reduced in degenerated areas compared to preserved areas, while the expression of all six IGF-binding protein genes examined was enhanced in the former areas. Consistent results were obtained by a protein analysis. In explant culture, the inhibition of AKT signaling abrogated the abundant matrix gene expression in the preserved areas over the degenerated areas, indicating that suppressed matrix synthesis in degenerated areas may be ascribed, at least partly, to attenuated IGF signaling. Within OA cartilage, the expression of Sp1 was considerably reduced in degenerated areas compared to preserved areas, which correlated well with the expression of IGF1R and IRS1. In experiments using primary cultured chondrocytes, the expression of IGF1R and IRS1 was enhanced by the induction of Sp1 expression and reduced by the suppression of Sp1 expression.Conclusions: The results of this study suggest that attenuated IGF signaling may be responsible, at least partly, for the reduced matrix synthesis in degenerated areas of OA cartilage.