bluuebunny/crossref_metadata_2025_split huggingface dataset:
اتجاهات طلبة جامعة بغداد / كلية التربية البدنية وعلوم الرياضة نحو المخدرات
Authors: Mahdi Abdalhadi Hameed , Mahdi Ali Maki , Ismaeil Karam Salam 
Published: July 2020

يهدف البحث الى التعرف على اتجاهات طلبة جامعة بغداد- كلية التربية البدنية وعلوم الرياضة من البنين والبنات وللمراحل اجمع نحو المخدرات ومقارنة الفروق بين الجنسين للسنة الدراسية 2018-2019 وطبق البحث على عينة قوامها 240 طالبا وطالبة وتوصلت الدراسة إلى ظهور اتجاهات ايجابية للبنين والبنات نحو تعاطي المخدرات مع وجود فروق معنوية ولصالح البنات علما ان قيمة الوسط للبنات والبنين اقل من قيمة المتوسط الفرضي والبالغ 110, وفي ضوء النتائج قدم الباحثون عددا من التوصيات والمقترحات ومنها ضرورة تنسيق الجامعات مع رجال الدين لعقد الندوات الهادفة حول الادمان ومخاطر ذلك على الفرد والمجتمع وتشجيعهم على تضمين خطبهم ودروسهم الدينية على دور العقل والروح والنفس في تكوين اتجاه مضاد لتعاطي المخدرات وتشجيع الرياضة بكافة مراحلها (المدرسية- الجامعية- العسكرية- الاندية والمنتخبات ) وينبغي العمل على مساعدة هؤلاء الشباب على تحقيق آمالهم وتقريبها من الواقع وتضييق الفجوة بين ما يسعون ويهدفون إليه والواقع الاجتماعي الملموس وإيصال برامج التوعية للأسر كي تقوم بدورها إزاء أبنائها في منظومة المكافحة الشاملة للمخدرات، وينبغي أن يكون للأسرة دور فاعل ومعتبر؛ فالأسرة تمثل خط الدفاع والحصانة الاجتماعية الأول والأبرز، فجهود المقاومة أو المكافحة ناقصة وعرضة للفشل إن لم تكن الأسرة واحدة من أركان هذه الجهود.
Improvement of Psychological Health Aspect of Tuberculosis Client Through Psychoeducation
Authors: Nisa Nurul Khoirun 
Published: July 2020

Introduction: Tuberculosis is well known as an infectious disease on lungs system caused by Mycobacterium tuberculosis in physical, social and mental health conditions.
Methods: This research applied quasi-experiment and consisted of pre and post-test on non-equivalent control group. The subjects were divided into two groups, control group (35) and treatment group (35) by using simple random sampling technique based on inclusion criteria. The research was conducted at Health Center, Jombang. The variables involved in this research were psycho-education psychological aspects.
Results: The results of the research showed that physical and psychological aspects on both treatment and control groups is with p = 0.000 (<0.05) which means that there is significant difference on psychological aspect between treatment and control groups. Psycho-education significantly influenced psychological among the patients with tuberculosis.
Conclusion: This change occurred due to the increase of health on the patient with tuberculosis in psychological aspects and also it followed by the decrease of symptoms on the patient.
Analisis Wisata Selam Berkelanjutan (Studi Kasus : Daya Dukung Lingkungan Terumbu Karang untuk Wisata Selam di Pulau Pari, Kepulauan Seribu)
Authors: Manaloe Oscar leonard 
Published: July 2020

Pulau Pari adalah gugusan dari Kepulauan Seribu yang terletak diantara 50 50’ LS–050 52’ LS dan 1060 34’ BT-1060 38’ BT. Pulau Pari yang memiliki potensi akan wisata, sehingga perlu adanya pengelolaan mengenai hal tersebut. Berdasarkan hal tersebut, maka perlu adanya analisis mengenai terumbu karang, daya dukung lingkungan, perilaku wisatawan, dan usulan mengenai pembagian kawasan konservasi perairan. Pendekatan riset yang dilakukan pada penelitian ini menggunakan mix method (kuantitatif dan kualitatif). Analisis yang digunakan pada riset ini adalah kondisi terumbu karang, data kelimpahan ikan karang, kesesuaian lahan perairan, daya dukung kawasan, dan analisis perilaku wisatawan. Hasil untuk kondisi tutupan terumbu karang di Pulau Pari pada Stasiun 1 dan stasiun 4 adalah kategori sangat buruk, Stasiun 2 kategori baik, dan Stasiun 3, stasiun 5, dan stasiun 6 termasuk dalam kategori buruk. Kelas kesesuaian pada Stasiun 2 adalah kategori sangat sesuai dan untuk kelas kesesuaian pada Stasiun 3 sampai dengan Stasiun 6 adalah kelas S2 atau sesuai. Pada analisis perilaku wisatawan sebanyak 50 responden, mendapatkan hasil bahwa wisata selam sendiri menyumbang 7,26% kerusakan terumbu karang. Daya dukung kawasan pada riset ini mendapatkan 221 orang/hari dan usulan pembagian kawasan menjadi 3 zona yaitu : zona perikanan berkelanjutan, zona pemanfaatan, dan zona rehabilitasi.
6.2. MACROECONOMIC AND MARKET FACTORS FOR PREDICTING REAL ESTATE PRICES IN THE EURO ZONE ON MIXED FREQUENCY DATA
Authors: Виноградов А.А. 
Published: July 2020

В данной работе исследуется динамика цен на недвижимость в зоне евро. Особенностями рынка недвижимости в зоне евро является разнородность стран, высокие объемы ипотечного рынка. Недвижимость является относительно неликвидным активом, а оценки ее стоимости публикуются реже, чем другие показатели. Актуальность работы заключается в построении модели для цены на недвижимость в зоне евро, которая позволяет построить прогноз и справедливую оценку для динамики цены на недвижимость. Новизной данной статьи является использование модель для данных смешанной частоты (MIDAS), которая позволяет совмещать высокочастотные рыночные показатели и низкочастотные данные по цене недвижимости для прогнозирования цен на жилую и коммерческую недвижимость. Среди факторов, влияющих на рынок недвижимости, были выделены ставки, отражающие состояние денежно-кредитной политики Европейского центрального банка (ЕЦБ) и объем активов ЕЦБ, отражающий меры нестандартной денежно-кредитной политики. В результате на основе высокочастотных данных была построена модель для цен на недвижимость, которая дает более точный прогноз, чем линейная модель, основанная только на квартальном росте валового внутреннего продукта зоны евро. Полученная модель может быть использована как для принятия управленческих решений, исходя из прогноза динамики цен на недвижимость, так и оценки справедливой динамики цен на недвижимость в зоне евро на основе фундаментальных факторов.
This paper examines the dynamics of real estate prices in the euro area. The features of the real estate market in the euro area is the heterogeneity of countries, high volumes of the mortgage market. Real estate is a relatively illiquid asset, and estimates of its value are published less frequently than other indicators. The relevance of the work is to build a model for real estate prices in the euro area, which allows one to build a forecast and a fair assessment for the price dynamics of real estate. The novelty of this article is the use of the mixed frequency data sampling model (MIDAS), which allows one to combine high-frequency market indicators and low-frequency data on the price of real estate, to predict the prices of residential and commercial real estate. Among the factors affecting the real estate market, the rates that reflect the state of the ECB's monetary policy and the volume of the ECB's assets reflecting the measures of a non-standard monetary policy were identified. As a result, based on high-frequency data, a model for real estate prices was built, which gives a more accurate forecast than a linear model based on only quarterly GDP growth in the euro area. The resulting model can be used both for making managerial decisions based on the forecast of real estate price dynamics, and for assessing the fair dynamics of real estate prices in the euro area based on fundamental factors.
2.1. USING TAKSONOMY XBRL IN ACCOUNTING, ANALYTICAL AND CONTROL PROCEDURES
Authors: Бурцева К.Ю. 
Published: July 2020

В исследовании изучены возможности применения технологий XBRL в учетном, аналитическом и контрольном инструментарии. Спецификации XBRL предоставляют собой технические аспекты создания документов для применения их пользователями в Интернете, также таксономии XRBL могут использоваться для улучшения функций и аппарата контроля, на их основе представляется возможным создание комплексной системы контроля, функционирующей на всех уровнях иерархии организации и во всех сферах ответственности. В статье изучены возможности применения технологий XBRL в различных аспектах деятельности организации. Исследован опыт компании Fujitsu, внедрившей XBRL во многих филиалах своей компании по всему миру, используя XML и XBRL для собственной внутренней стандартизации и отчетности. Выделены преимущества применения XBRL для целей документирования и представления информации о внутреннем контроле. Предложено использовать опыт зарубежных компаний для повышения прозрачности отчетности, эффективности мониторинга аспектов управления и контроля, также рекомендовано разрабатывать и внедрять таксономию XBRL корпоративного управления, которая согласуется с таксономиями финансовой отчетности для сбора нефинансовой информации о компании, касающейся политики управления, прав и обязанностей акционеров, информации о директорах. Стандартизация бизнес-отчетности с применением технологий XBRL поможет обеспечить прозрачность для инвесторов и кредиторов, облегчая функций мониторинга и контроля для регуляторных и надзорных органов.
The study examined the possibilities of using XBRL technologies in accounting, analytical and control tools. XBRL specifications provide the technical aspects of creating documents for use by users on the Internet, XRBL taxonomies can also be used to improve control functions, it seems possible to create a comprehensive control system that operates at all levels of the organization hierarchy and in all areas of responsibility. The article explores the possibilities of using XBRL technology in various aspects of the organization. The experience of Fujitsu, which has implemented XBRL in many branches of its company around the world, using XML and XBRL for its own internal standardization and reporting, is examined. The advantages of using XBRL for documenting and reporting internal control information are highlighted. It is proposed to use the experience of foreign companies to increase transparency of reporting, monitor the effectiveness of management and control aspects, it is also recommended to develop and implement a corporate governance XBRL taxonomy, which is consistent with the taxonomy of financial reporting to collect non-financial information about the company regarding management policies, rights and obligations of shareholders, information about directors. Standardizing business reporting with XBRL technology will help ensure transparency for investors and lenders by facilitating monitoring and control functions for regulators and supervisors.
7.6. Business planning for innovative startups
Authors: Ханафиева И.Р. 
Published: July 2020

В статье рассмотрены теоретические основы бизнес-планирования стартапа. Раскрыта сущность бизнес-плана как специального инструмента, используемого в современной рыночной экономике в качестве средства контроля и управления бизнесом.Определена важность соблюдения сбалансированности основных разделов бизнес-плана стартапа: необходимо, чтобы описательная часть и финансовый план согласовывались друг с другом, поскольку по отдельности они не отражают инновационную идею полностью.Рассмотрены функции бизнес-плана и задачи, на решение которых направлен бизнес-план в процессе достижения поставленной цели. Представлена последовательная структура бизнес-плана стартапа (инновационного проекта).
The article discusses the theoretical foundations of start-up business planning as a process where a business plan is a business card necessary to attract financial resources. The essence of the business plan as a special management tool used in the modern market economy as a means of monitoring and managing the business is revealed.The importance of balancing the main sections of the start-up business plan is determined: it is necessary that the narrative and financial plan are consistent with each other, because individually they do not fully reflect the innovative idea.The functions of the business plan and the tasks that are addressed by the business plan in the process of achieving this goal are considered. The consistent structure of a start-up business plan or innovation project is presented.The process of preparing a business plan for start-ups is a complex and time-consuming process, as a result of which the most well-known Western methods for developing business plans for innovative start-ups, which are the basis of Russian methods, are considered.
3.2. Transformation of the economic environment under the influence of digitalization
Authors: Морозко Н.И. , Бакулина А.А. 
Published: July 2020

На современном этапе инновации выступают направлением выхода из циклических кризисов на основе использования новейших цифровых технологий. В цифровом пространстве изменяются методы бизнеса, обеспечивающие получение более высокой добавленной стоимости в производстве товаров, работ и услуг. В работе использован системно-структурный метод анализа фаз экономического развития в контексте экономической теории больших циклов. Воздействие цифровых технологий приводит к эволюции всех существующих форм экономического взаимодействия.
At the present stage, innovation is the direction of getting out of cyclical crises through the use of the latest digital technologies. In the digital space, business methods are changing to ensure higher value added in the production of goods, works. A system-structural method of analysis of the phases of economic development in the context of the economic theory of large cycles is used in the work. The impact of digital technologies leads to the evolution of all existing forms of economic interaction.
7.4. EMS OF AIRCRAFT INDUSTRY HARDWARE DEVELOPMENT STRATEGIC PLANNING
Authors: Клочков В.В. 
Published: July 2020

На примере авиационной промышленности рассматриваются проблемы стратегического планирования материально-технической базы (МТБ) высокотехнологичной промышленности. Показано, что этот важнейший аспект стратегического планирования сейчас не нашел адекватного отражения в системе управления на отраслевом и корпоративном уровнях, выявлены другие институциональные проблемы. Обоснована двусторонняя взаимосвязь продуктовой стратегии и стратегии развития МТБ высокотехнологичных предприятий и отраслей. Особое внимание уделено стратегическому планированию развития производственных технологий, а также экспериментальной базы.
The problems of strategic planning of high-tech industry hardware are considered on the example of aircraft industry. It is shown that this important aspect of strategic planning has not been adequately reflected in the management system at the sectoral and corporate levels, and other institutional problems have been identified. The bilateral interrelation of the hi-tech enterprises and branches product strategy and strategy of hardware development is proved. Special attention is paid to the strategic planning of the d
Efficient validated method of HPLC to determine amlodipine in combinated dosage form containing amlodipine, enalapril and bisoprolol and in vitro dissolution studies with in vitro/ in vivo correlation
Authors: Logoyda Liliya 
Published: July 2020

Aim. A rapid and reproducible HPLC method has been developed for the determination of amlodipine in experimental combined dosage forms containing amlodipine, bisoprolol and enalapril and for drug dissolution studies.
Materials and methods. The separation was done using a column Phenomenex Polar Synergi, 5 μm, 4.6×50 mm and a mobile phase of methanol:phosphate buffer solution (65:35, v/v), flow-rate of 1.0 mL/min. The injection volume was 100 μL and the ultraviolet detector was set at 240 nm.
Results. The method was validated as per ICH guidelines. Under these conditions, amlodipine was eluted at 1.89 min. Total run time was shorter than 2.5 min. The linearity of the method had a good correlation with concentration and peak area. The correlation coefficient of amlodipine was found to be not less than 0.9991, which indicates good linear relationship over concentration range 0.625 mg/mL–5.000 mg/mL (1.250 mg/mL–5.000 mg/mL at pH 4.5). The % RSD values in intra-day and inter-day precision study were found to be less than 0.267 for amlodipine, which indicate method was precise. Hence, the present developed method was said to be suitable for the analysis of drugs in their pharmaceutical dosage form. Also, in vitro dissolution of amlodipine containing tablets were performed to validate the suitability of the proposed method. The dissolution pattern complies with the FDA standards, indicating suitability of the proposed method for the dissolution study of amlodipine. It will allow conducting comparative studies in vitro to confirm the equivalence of tablets containing amlodipine.
Conclusion. A simple and sensetive HPLC method was developed for the estimation of amlodipine in tablets containing amlodipine, enalapril and bisoprolol. The proposed method was applied successfully for quality control assay of amlodipine in experimental tablets and in vitro dissolution studies. In vitro / in vivo correlation of amlodipine has been conducted.
HPLC-MS/MS method development for the quantitative determination of nifedipine for Caco-2 permeability assay
Authors: Logoyda Liliya 
Published: July 2020

Aim. Poorly water-soluble drugs such as nifedipineoffer challenging problems in drug formulation as poor solubility is generally associated with poor dissolution characteristics and thus with poor oral bioavailability (BCS class II drugs). Methods of quantitative determination of nifedipine by methods of spectrophotometry and chromatography are described in the scientific literature. However, methods are not developedfor examination of nifedipine from Caco-2 cell monolayers. Caco-2 cell monolayers have been extensively used for years as a tool to test permeability, assess the oral absorption potential and study the absorption mechanism of compounds. Therefore, the aim of this study was to develop and validate an efficient HPLC MS/MS method for determination of nifedipine from Caco-2 cell monolayers.
Materials and methods. Chromatography was achieved on DiscoveryC18, 50 × 2.1 mm, 5 μm column. Samples were chromatographed in a gradient mode (eluent A (acetonitrile – water – formic acid, 5 : 95 : 0.1 v/v), eluent B (acetonitrile – formic acid, 100 : 0.1 v/v)). The initial content of the eluent B is 0%, which increases linearly by 1.0 min to 100% and to 1.01 min returns to the initial 0%. The mobile phase was delivered at a flow rate of 0.4 mL/min into the mass spectrometer ESI chamber. The sample volume was 5 μl.
Results. Under these conditions, nifedipine was eluted at 1.83 min. A linear response function was established at 1 – 100 ng/mL. The regression equation for the analysis was Y = 0.0323x-0.00121 with coefficient of correction (R2) = 0.9987. According to the Caco-2 test results, nifedipine showed high permeability. The within-run coefficients of variation ranged between 0.331% and 0.619% for nifedipine. The within-run percentages of nominal concentrations ranged between 98.80% and 100.63% for nifedipine. The between-run coefficients of variation ranged between 0.332% and 0.615% for nifedipine. The between-run percentages of nominal concentrations ranged between 98.98% and 101.71% for nifedipine. The assay values on both the occasions (intra- and inter-day) were found to be within the accepted limits.
Conclusion. From results of analysis, it can be concluded that developed method is simple and rapid for determination of nifedipine from confluent Caco-2 monolayers and from aqueous solution. Acquired results demonstrate that proposed strategy can be effortlessly and advantageously applied for examination of nifedipine from Caco-2 cell monolayers.
Bioanalytical method development and validation for the determination of metoprolol and meldonium in human plasma
Authors: Horyn Mariana , Logoyda Liliya 
Published: July 2020

Aim.The main purpose of this study was to develop a simple, precise, rapid and accurate method for the quantification of metoprolol and meldonium in human plasma.
Materials and methods. The resolution of peaks of metoprolol was best achieved with Discovery C18, 50 × 2.1 mm, 5 μm column and meldonium - ZORBAX HILIC Plus, 50 × 2.1 mm, 3.5 μm column. Samples of metoprolol were chromatographed in a gradient mode (eluent A (acetonitrile – water – formic acid, 5 : 95 : 0.1 v/v), eluent B (acetonitrile – formic acid, 100 : 0.1 v/v)). The initial content of the eluent B is 0%, which increases linearly by 1.0 min to 100% and to 1.11 min returns to the initial 0%. The mobile phase was delivered at a flow rate of 0.400 mL/min into the mass spectrometer ESI chamber. The injection volume was 5μl. Samples of meldonium were chromatographed in a isocratic using mobile phase water – acetonitrile – ammonium formate buffer 200 мМ, 20 : 75 : 5 v/v).
Results.The total chromatographic run time was 2.0 minutes and the elution of metoprolol, meldonium and IS occurred at ~1.39 and 1.18 minutes, respectively.A linear response function was established at 2 - 200 ng/mL for metoprolol and 50 -5000 ng/mL for meldonium in human plasma. The% mean recovery for metoprolol in LQC, MQC and HQC was 99.0%, 107.5% and 96.8%, for meldonium in LQC, MQC and HQC was 94.1%, 100.2% and 93.1% respectively. The lowest concentration with the RSD &lt;20% was taken as LLOQ and was found to be 2.31 ng/mL for metoprolol, 47.70 ng/mL for meldonium. The % accuracy of LLOQ samples prepared with the different biological matrix lots were found 115.4% for metoprolol and 95.5% for meldonium, which were found within the range of 80.00–120.00% for the seven different plasma lots. % CV for LLOQ samples was observed as 12.8% and 7.7% respectively, which are within 20.00% of the acceptance criteria.
Conclusion.A rapid method was developed for simultaneous determination of metoprolol and meldonium in human plasma. The method was strictly validated according to the ICH guidelines. Acquired results demonstrate that proposed strategy can be effortlessly and advantageously applied for routine examination of metoprolol and meldonium in human plasma.
4. La méthode photovoix
Authors: Rey Lynda , Affodégon Wilfried , Viens Isabelle , Fathallah Hind , José Arauz Maria 
Published: July 2020

Utiliser des méthodes évaluatives adaptées à la fois au contexte d’intervention, à l’objet de l’évaluation et aux populations ciblées est essentielle en évaluation de programmes. Toutefois, cela comporte des défis non négligeables dans le cas d’interventions complexes et de communautés marginalisées. Dans ce chapitre, nous présentons une méthode d’évaluation participative utilisant la photo comme support d’expression – la photovoix, – , particulièrement adaptée aux jeunes et aux communautés autochtones ciblées par un projet d’accès à l’eau, l’hygiène et l’assainissement au Mexique. Cette méthode qualitative a aussi été choisie pour son caractère créatif et artistique permettant de répondre à l’objectif de l’évaluation : évaluer les perceptions des jeunes par rapport aux activités artistiques auxquelles ils ont participé dans le cadre de la composante Art Social pour le Changement de Comportement ; les encourageant à adopter de meilleures pratiques en lien avec l’eau potable et l’hygiène. Les forces et les faiblesses de cette méthode sont exposées et le processus méthodologique décrit en détail. Les résultats de l’intervention mis en évidence par ce processus sont brièvement présentés et enfin, les leçons tirées de l’application de la photovoix sont décrites afin d’encourager l’utilisation de cette méthode qui s’est avérée particulièrement utile et concluante dans le cas présenté.