bluuebunny/crossref_metadata_2025_split huggingface dataset:
MODAL AND STRUCTURAL ANALYSIS STUDIES OF THE TRANSFER LINE CARRIER CONSTRUCTION
Authors: VOLKAN Barış 
Published: June 2020

In this study, the analysis studies carried out to assist the design stages of the part transfer line to be used in an automobile factory and the experiences gained from these analysis studies are emphasized. These experiences are very important in similar product developments in industrial design. Design and analysis studies carried out prior to manufacturing ensure that production can be carried out without any problems. For this reason, special importance should be given to the design stages in the process and alternative solutions should be created by revising the design in every aspect. Analysis studies should be carried out to select the best design among these solutions. The finite element approach, which is the approach used by today's special analysis software, was preferred in this study. Many analyses were carried out on the model whose boundary conditions were determined and the real-life behaviour of the design was foreseen. In the analysis studies, modal analyses and structural displacements were carried out in order to understand the dynamic behaviours and the stresses will not exceed certain limits. A finite element based simulation software was used in the analysis studies. Here, the importance of design experiences based on past experiences has emerged in the optimization of the design.
The design steps to be presented in the paper and the analysis results obtained through the design were also very useful in the prototype manufacturing phase and the transfer line was safely demonstrated. As a result of the trials, the transfer line was delivered to the customer and still fulfils its duty safely.
SAC ŞEKİLLENDİRME İŞLETMESİNDE SMED ÇALIŞMASINA BİR ÖRNEK
Authors: Edis Rabia , Yalçın Caner , Sınmazçelik Tamer , Özzaim Pelin , Durali Haluk , Yurdakul Yiğit 
Published: June 2020

SMED, Single Minute Exchange of Dies (Tekli Dakikalarda Kalıp Değişimi), üretim süreci boyunca oluşan kalıp değişiminden kaynaklanan kayıpları minimize etmek için kullanılan önemli bir yöntemdir. Özellikle otomotiv sektöründe saniyeler bile önemli iken dikkatsiz tasarlanan kalıplar ve bu yanlış tasarımın bir sonucu olarak uzun süren kalıp değişim süreleri üretimi ciddi anlamda olumsuz etkilemektedir ve verimliliği düşürmektedir. Mümkün olan en kısa sürede, en kaliteli ürünü üretmek günümüzün önemli gereksinimlerindendir. Bu kapsamda SMED yöntemi bu çalışmanın temel kaynağı olarak kullanılmıştır.
Bu çalışmada, işletmede kullanılan manuel pres hattında üretilen 6 farklı ürün için kullanılan kalıplar referans alınmıştır. Bu 6 ürün manuel üretimin %85’ini oluşturan ürünlerdir. Ürünler maksimum 5 farklı manuel pres kullanılarak üretilmektedir. Bu preslerde ürünlerin kalıp değişim süreleri 3,5 aylık bir gözlem sonucu belirlenmiştir. Bu süreler detaylı bir şekilde incelenerek, kalıp tasarımından veya kullanılan bağlama ekipmanlarından kaynaklı olduğu tespit edilmiştir. Kalıplar üzerinde yapılabilecek iyileştirmeler ve kullanılan ekipmanlarda yapılacak yenilikler veya iyileştirmeler belirlenmiştir. Gerekli iyileştirmeler yapıldığı zaman oluşacak kazanç hesaplanarak SMED yaklaşımının sac imalat sektörüne etkisi hakkında kantitatif sonuçlar verilmiştir.
Cross Layer Based Cooperative Communication Protocol for Improving Network Performance in Underwater Sensor Networks
Authors: Kim Kihyun , Kim Sunmyeng 
Published: June 2020

For underwater sensor networks (USNs), cooperative communications have been introduced to improve network performance with the help of relay nodes. The previous cooperative communications select the best relay node on a hop-by-hop basis. Therefore, they have limitations in improving performance. In order to get better performance, a cooperative communication protocol based on the cross layer is proposed in this paper. The proposed protocol uses the information provided by a routing protocol at the network layer for the erroneous data packet delivery. It selects one with the minimum routing cost among relay candidate nodes. The routing protocol in the selected relay node provides the MAC layer with the address of the next hop node on the path to the sink node. Then, the MAC layer in the selected relay node forwards the erroneous data packet to the next hop node rather than a receiver node. Performance studies are carried out through simulation. Simulation results show that the proposed protocol has about 21.8% lower average delay and about 14.4% lower average number of nodes passed than the previous protocol, regardless of the maximum transmission range.
Pluralidad ciudadana y unidad del cuerpo político
Authors: Ternavasio Marcela 
Published: June 2020

El presente artículo es en un breve ejercicio de reflexión sobre algunos de los dilemas que abrió la coexistencia de los dos dispositivos de organización política moderna: la representación electoral y el principio de división de poderes. Para ilustrarlos se analiza el caso del Río de la Plata en dos momentos sucesivos de la primera mitad del siglo XIX. El objetivo del ejercicio es recrear muy rápidamente los ambientes políticos y los horizontes de ideas que atravesaron a ambos momentos y presentar de manera estilizada las alternativas que se fueron configurando sobre un problema más general que puede hacerse extensivo a los experimentos políticos que se estaban ensayando en las nuevas comunidades soberanas surgidas del colapso de los imperios.
TAX REVENUE AND ECONOMIC GROWTH NEXUS: EMPIRICAL EVIDENCE FROM THE NIGERIAN ECONOMY
Authors: Agunbiade Olabode , Idebi Alesanmi Abraham 
Published: June 2020

<p>This paper examined the relationship between tax revenue and economic growth in Nigeria over 1981–2019 period, with special focus on Companies Income Tax, Value Added Tax and Petroleum Profits Tax. The data were sourced from the National Bureau of Statistics (NBS) and the Federal Inland Revenue Service (FIRS). The study employed the Vector Error Correction Model (VECM) to establish the nature and strength of the relationship between taxation and economic growth. The Johansen test of cointegration reveals that there is at least one cointegrating equation in the long-run between the variables. Granger causality test found a causal relationship among Real GDP and the different tax components. The impulse response functions and the variance decomposition analysis uphold the findings that the impact of the shock in the indirect tax (VAT) and direct tax (CIT and PPT) on GDP growth does not die out over the specified period under consideration. Variance decomposition analysis found that the effect of the shock to the direct tax (CIT and PPT) on GDP growth tends to be low, whereas the effect of the shock to the indirect tax (VAT) on GDP growth tends to be significant to increase over the period. Therefore, this study recommended that in order to expand tax revenue, there should be a broad base tax strategy, focusing on all key areas of the tax system with measurable outcomes. Emphasis should be on simplification of the tax system and ease of implementation with priority given to quick wins and low hanging fruits, while more challenging aspects should be deferred until positive results are being recorded. The regulatory authorities charged with the responsibility of collecting tax should further be strengthened to enforce compliance by taxpayers, among other recommendations.</p><p> </p><p><strong>JEL: </strong>C1, H20, H21</p>
There Isn’t Belief, Just Believing: RethinkingBeliefas a Keyword of Folklore Studies
Authors: Gatling Benjamin 
Published: June 2020

AbstractBelief as a term in folklore scholarship encompasses a range of competing concepts. This article posits a number of problems with belief’s standard usage: beliefs are reified and abstracted from social action; beliefs are systematized and explanatory of behavior; and beliefs are rendered as universal, cross-cultural features of social life. This article argues that reconceptualizing belief carries with it a decolonial justice imperative, and folklorists should jettison belief as a keyword of the discipline.
Death by cat bite: Pasteurella multocida: Autopsy findings and review of the literature
Authors: Humphrey William , Crothers Jessica W. , Stowman Anne M. , Mount Sharon L. 
Published: June 2020

Pasteurella multocida, a gram-negative bacillus, is present in the oropharyngeal secretions of livestock, wild animals, and domesticated pets and can cause infection in humans. The most common route of entry has been shown to be via an animal bite, but a significant portion of cases of human infection lack evidence of such a wound. Review of the literature reveals that patients with a history of an animal bite tend to have a less aggressive clinical course than patients without an animal source of infection. We present a case, however, of Pasteurella multocida bacteremia which resulted in the death of an immunocompromised 80-year old woman in which the route of infection was found at autopsy to be a cat bite. This case highlights the importance of educating patients, particularly those with underlying immunocompromised conditions, of the possible lethal complications that can result from animal inflicted wounds and the importance of seeking medical assistance should a bite occur.
SPANXN2 functions a cell migration inhibitor in testicular germ cell tumor cells
Authors: Zhu Fang , Bo Hao , Liu Guangmin , Li Ruixue , Liu Zhizhong , Fan Liqing 
Published: June 2020

Background
SPANX family members are thought to play an important role in cancer progression. The SPANXN2 is a gene expressed mainly in normal testis, but its role in testicular germ cell tumors (TGCTs) has yet to be investigated. TGCT is one of the most common solid tumors in young men and is associated with poor prognosis; however, effective prognostic indicators remain elusive. Therefore, we investigated the role of SPANXN2 in TGCT development.

Methods
SPANXN2 expression levels were validated by quantitative real-time polymerase chain reaction (qRT-PCR) analyses of 14 TGCT samples and five adjacent normal tissue samples. SPANXN2 was transiently overexpressed in TGCT cells to study the consequences for cell function. The effects of SPANXN2 on cell migration were evaluated in transwell and wound healing assays. The effects on cloning ability were evaluated in colony formation assays. MTT assays and cell cycle analysis were used to detect the effects of SPANXN2 on cell proliferation. The expression levels of EMT- and AKT-related proteins in cells overexpressing SPANXN2 were analyzed by Western blotting.

Results
Compared with adjacent normal tissues, the Gene Expression Profiling Interactive Analysis database showed SPANXN2 expression was downregulated in TGCTs which was consistent with the qRT-PCR analysis. SPANXN2 overexpression reduced cell migration and colony formation capability and downregulated expression of EMT- and AKT-related proteins, Vimentin, Snail, AKT, and p-AKT.

Conclusion
Our results suggest that SPANXN2 regulates TGCT cell migration via EMT- and AKT-related proteins although its role in the occurrence and development of TGCT remains to be fully elucidated.
An indirect high iodine (131I) effective dose used for thyroid ablation in patients with thyroid cancer. Is the method of measurement important?
Authors: Al‐Shakhrah Issa A. 
Published: June 2020

AbstractBackgroundRadiation effective dose to the red bone‐marrow, a critical organ in the therapy of differentiated thyroid carcinoma (DTC) with radioiodine‐131 (131I), cannot be measured directly. As radioiodine concentration is comparable in blood and most organs, and is believed to be similar in red marrow, the effective dose to the blood seems to be a good first‐order approximation of the radiation effective dose to the hematopoietic system and a better means to quantifying exposure from therapy compared to the total amount of activity administered.PurposeWe applied four formulas (Lassmann et al (standard) [2008], Eur J Nucl Med Molecul Imaging, 35:1405–1412), (Thomas et al. [1993], Nucl Med Biol, 20:157–162), (Sisson et al. [2003], J Nucl Med, 44:898–903; Ha¨nscheid et al. [2009], Endocr Relat Cancer, 16:1283–1289) and (Ha¨nscheid et al. [2006], J Nucl Med, 47:648–654) and compared between the estimated values of the effective dose that were obtained by three formulas and those obtained by the standard one.Materials and methodsTwenty‐seven patients, 22 women and 5 men, suffering from DTC were enrolled in this study. Whole‐body probe measurements and blood collections (2 mL whole‐blood samples) were conducted at 2, 6, 24, 48, 72–96 h after the administration of 131I to obtain time–activity curves. Whole‐body measurements were performed as conjugate view (anterior and posterior) counts by scintillation camera imaging.ResultsBy comparing the values of blood effective dose that were obtained by applying Thomas et al. [1993], Nucl Med Biol, 20:157–162; Sisson et al. [2003], J Nucl Med, 44:898–903 and Ha¨nscheid et al. [2009], Endocr Relat Cancer, 16:1283–1289, and Ha¨nscheid et al. [2006], J Nucl Med, 47:648–654, techniques, with those obtained by (Lassmann et al (standard technique) [2008], Eur J Nucl Med Molecul Imaging, 35:1405–1412), we found that these values are, respectively, 15.0%, 40.0%, and 41.0% more than those obtained by using the standard method. To our knowledge no papers have been published previously that compare between these dosimetric approaches.ConclusionHighly overestimated or highly underestimated results obtained by a certain method or technique, compared with those obtained by the standard method, are not desirable, they tend to exaggerate in applying radiation protection procedures, by increasing or decreasing, which, in both cases, become far from the realistic or recommended procedures. As an operating philosophy, the objective of radiation safety practices simply should not be to keep radiation doses within legal limits or maximum permissible doses (MPDs), but to keep them “as low as reasonably achievable” (ALARA concept). MPDs should not be considered as thresholds below which exposure to radiation is of no concern, they are not assumed to be totally risk free, and any reasonable technique for reducing radiation dose may have potential benefits in the long run.
Imidazodipyridines via DMAP Catalyzed Domino N−H Carbonylation and 6π‐Electrocyclization: Synthetic Scope and Application
Authors: Zhang Kena , El Bouakher Abderrahman , Lévaique Hélène , Bignon Jérome , Retailleau Pascal , Alami Mouad , Hamze Abdallah 
Published: June 2020

AbstractIn this work, we report a domino reaction for access to highly functionalized imidazo[1,2‐a:5,4‐b′]dipyridines simply by stirring Boc2O in the presence of DMAP as a catalyst with readily prepared 3‐amino‐2‐(vinyl)imidazo[1,2‐a]pyridine. This methodology enables the synthesis of highly functionalized imidazodipyridines. The process proved to be compatible with a wide variety of substrates. The synthetic potential of this method was illustrated by performing a Suzuki‐Miyaura coupling on 4‐phenylimidazo‐dipyridin‐2‐ol derivatives. Screening of the biological activity of the newly generated compounds led to the identification of a new hit. Compound 7 l exhibits good antiproliferative activity in the submicromolar range against the human colon cancer cell line.magnified image
Diffuse infantile hepatic hemangiomas in a patient with Beckwith–Wiedemann syndrome: A new association?
Authors: Macchiaiolo Marina , Markowich Anna H. , Diociaiuti Andrea , Gonfiantini Michaela V. , Buonuomo Paola S. , Rana Ippolita , Monti Lidia , El Hachem May , Bartuli Andrea 
Published: June 2020

AbstractBeckwith–Wiedemann syndrome (BWS) is an overgrowth syndrome, caused by alterations in a cluster of imprinted genes located within the chromosome region 11p15.5. Common clinical features are overgrowth, macroglossia, lateralized overgrowth, abdominal wall defects, neonatal hypoglycemia and an increased risk of embryonal tumors, such as hepatoblastomas. Periodic screening for abdominal tumors is recommended. Vascular tumors are uncommon in BWS. Diffuse infantile hepatic hemangiomas (DIHHs) are rare vascular tumors with potentially lethal complications, in particular acquired consumptive hypothyroidism, high‐output cardiac failure, liver failure and abdominal compartment syndrome. We describe a 2‐month‐old patient with hallmark clinical features of BWS and confirmed a genetic diagnosis with mosaic paternal uniparental disomy of chromosome 11p15.5 (UPD[11]pat). The patient developed hepatomegaly and elevated alpha‐fetoprotein (AFP) and was therefore suspected of having a hepatoblastoma. Abdominal echo‐color Doppler and a CT‐scan allowed diagnosis of DIHHs. She was closely monitored and underwent treatment with propranolol. Oral propranolol was effective in reducing hepatic lesions without side effects. This report may suggest that vascular tumors can also be associated with BWS.
Genome‐wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways
Authors: Sherva Richard , Gross Alden , Mukherjee Shubhabrata , Koesterer Ryan , Amouyel Philippe , Bellenguez Celine , Dufouil Carole , Bennett David A. , Chibnik Lori , Cruchaga Carlos , del‐Aguila Jorge , Farrer Lindsay A. , Mayeux Richard , Munsie Leanne , Winslow Ashley , Newhouse Stephen , Saykin Andrew J. , Kauwe John S.K. ,   the Alzheimer's Disease Genetics Consortium, Crane Paul K. , Green Robert C. 
Published: June 2020

AbstractIntroductionVariability exists in the disease trajectories of Alzheimer's disease (AD) patients. We performed a genome‐wide association study to examine rate of cognitive decline (ROD) in patients with AD.MethodsWe tested for interactions between genetic variants and time since diagnosis to predict the ROD of a composite cognitive score in 3946 AD cases and performed pathway analysis on the top genes.ResultsSuggestive associations (P < 1.0 × 10−6) were observed on chromosome 15 in DNA polymerase‐γ (rs3176205, P = 1.11 × 10−7), chromosome 7 (rs60465337,P = 4.06 × 10−7) in contactin‐associated protein‐2, in RP11‐384F7.1 on chromosome 3 (rs28853947, P = 5.93 × 10−7), family with sequence similarity 214 member‐A on chromosome 15 (rs2899492, P = 5.94 × 10−7), and intergenic regions on chromosomes 16 (rs4949142, P = 4.02 × 10−7) and 4 (rs1304013, P = 7.73 × 10−7). Significant pathways involving neuronal development and function, apoptosis, memory, and inflammation were identified.DiscussionPathways related to AD, intelligence, and neurological function determine AD progression, while previously identified AD risk variants, including the apolipoprotein (APOE) ε4 and ε2 variants, do not have a major impact.
A Multi‐responsive Fluorescent Probe Reveals Mitochondrial Nucleoprotein Dynamics with Reactive Oxygen Species Regulation through Super‐resolution Imaging
Authors: Yang Guanqing , Liu Zhengjie , Zhang Ruilong , Tian Xiaohe , Chen Juan , Han Guangmei , Liu Bianhua , Han Xinya , Fu Yao , Hu Zhangjun , Zhang Zhongping 
Published: June 2020

AbstractUnderstanding the biomolecular interactions in a specific organelle has been a long‐standing challenge because it requires super‐resolution imaging to resolve the spatial locations and dynamic interactions of multiple biomacromolecules. Two key difficulties are the scarcity of suitable probes for super‐resolution nanoscopy and the complications that arise from the use of multiple probes. Herein, we report a quinolinium derivative probe that is selectively enriched in mitochondria and switches on in three different fluorescence modes in response to hydrogen peroxide (H2O2), proteins, and nucleic acids, enabling the visualization of mitochondrial nucleoprotein dynamics. STED nanoscopy reveals that the proteins localize at mitochondrial cristae and largely fuse with nucleic acids to form nucleoproteins, whereas increasing H2O2 level leads to disassociation of nucleic acid–protein complexes.
Persistent Room Temperature Phosphorescence from Triarylboranes: A Combined Experimental and Theoretical Study
Authors: Wu Zhu , Nitsch Jörn , Schuster Julia , Friedrich Alexandra , Edkins Katharina , Loebnitz Marcel , Dinkelbach Fabian , Stepanenko Vladimir , Würthner Frank , Marian Christel M. , Ji Lei , Marder Todd B. 
Published: June 2020

AbstractAchieving highly efficient phosphorescence in purely organic luminophors at room temperature remains a major challenge due to slow intersystem crossing (ISC) rates in combination with effective non‐radiative processes in those systems. Most room temperature phosphorescent (RTP) organic materials have O‐ or N‐lone pairs leading to low lying (n, π*) and (π, π*) excited states which accelerate kisc through El‐Sayed's rule. Herein, we report the first persistent RTP with lifetimes up to 0.5 s from simple triarylboranes which have no lone pairs. RTP is only observed in the crystalline state and in highly doped PMMA films which are indicative of aggregation induced emission (AIE). Detailed crystal structure analysis suggested that intermolecular interactions are important for efficient RTP. Furthermore, photophysical studies of the isolated molecules in a frozen glass, in combination with DFT/MRCI calculations, show that (σ, B p)→(π, B p) transitions accelerate the ISC process. This work provides a new approach for the design of RTP materials without (n, π*) transitions.
Metal–Ligand Cooperativity of the Calix[4]pyrrolato Aluminate: Triggerable C−C Bond Formation and Rate Control in Catalysis
Authors: Ebner Fabian , Sigmund Lukas Maximilian , Greb Lutz 
Published: June 2020

AbstractMetal‐ligand cooperativity (MLC) had a remarkable impact on transition metal chemistry and catalysis. By use of the calix[4]pyrrolato aluminate, [1]−, which features a square‐planar AlIII, we transfer this concept into the p‐block and fully elucidate its mechanisms by experiment and theory. Complementary to transition metal‐based MLC (aromatization upon substrate binding), substrate binding in [1]− occurs by dearomatization of the ligand. The aluminate trapps carbonyls by the formation of C−C and Al−O bonds, but the products maintain full reversibility and outstanding dynamic exchange rates. Remarkably, the C−C bonds can be formed or cleaved by the addition or removal of lithium cations, permitting unprecedented control over the system's constitutional state. Moreover, the metal‐ligand cooperative substrate interaction allows to twist the kinetics of catalytic hydroboration reactions in a unique sense. Ultimately, this work describes the evolution of an anti‐van't Hoff/Le Bel species from their being as a structural curiosity to their application as a reagent and catalyst.
Magnetically Induced CO2Methanation Using Exchange‐Coupled Spinel Ferrites in Cuboctahedron‐Shaped Nanocrystals
Authors: Rivas‐Murias Beatriz , Asensio Juan M. , Mille Nicolas , Rodríguez‐González Benito , Fazzini Pier‐Francesco , Carrey Julian , Chaudret Bruno , Salgueiriño Verónica 
Published: June 2020

AbstractMagnetically induced catalysis can be promoted taking advantage of optimal heating properties from the magnetic nanoparticles to be employed. However, when unprotected, these heating agents that are usually air‐sensitive, get sintered under the harsh catalytic conditions. In this context, we present, to the best of our knowledge, the first example of air‐stable magnetic nanoparticles that: 1) show excellent performance as heating agents in the CO2methanation catalyzed by Ni/SiRAlOx, with CH4yields above 95 %, and 2) do not sinter under reaction conditions. To attain both characteristics we demonstrate, first the exchange‐coupled magnetic approach as an alternative and effective way to tune the magnetic response and heating efficiency, and second, the chemical stability of cuboctahedron‐shaped core–shell hard CoFe2O4–soft Fe3O4nanoparticles.