bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ethnobotanical study on wild edible plants used by three trans-boundary ethnic groups in Jiangcheng County, Pu' er, Southwest China
Authors: Cao Yilin , li ren , Zhou Shishun , Song Liang , Quan Ruichang , Hu Huabin 
Published: October 2020

Abstract
Background: Dai, Hani, and Yao people, in the trans-boundary region between China, Laos, and Vietnam, have gathered plentiful traditional knowledge about wild edible plants during their long history of understanding and using natural resources. The ecologically rich environment and the multi-ethnic integration provide a valuable foundation and driving force for high biodiversity and cultural diversity in this region. However, little study has uncovered this unique and attractive culture to the world. Methods: We conducted Ethnobotanical survey in 20 villages of Jiangcheng County from 2016 to 2020. Altogether 109 local Dai, Hani, and Yao people were interviewed, and their traditional knowledge about wild edible plants was recorded. Voucher specimens were identified by the authors and deposited in the herbarium of Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences (HITBC). The use value was used as a quantitative index to evaluate the consume frequency and relative importance of the wild edible plants. The Jaccard index was calculated to assess the usage similarity of different areas. The relationship of age and recognized wild edible plants by different ethnic people was performed by R. Results: A total of 211 wild edible plants, belonging to 71 families and 151 genera, were recorded. These plants were consumed as wild edible vegetables, seasonal fruits, salads, spices, sour condiments, tonic soups, tea substitutes, liquor brewing, or dyeing materials. The use value (UV), current cultivation, market availability, as well as the quantitative traditional knowledge inheritance situation of these wild edible plants among different generations were analyzed. Based on the data from threatened species list of China’s higher plants and the IUCN Red List, the food plant list for Asia Elephant, the Subject Database of China Plant and the calculated UV score, the top 30 most important wild edible plants were selected for further cultivation in some local villages. Conclusion: Traditional knowledge of wild edible plants, owned by Dai, Hani, and Yao people in Jiangcheng County, is rich but at risk of being lost among the young generation. Diversified cultivation of wild edible plants by the local communities could be a solution for sustainable use of natural resources and to conserve the endangered species in this trans-boundary region.
Digital Consultations in Swedish Primary Health Care: A Qualitative Study of Physicians’ Job control, Demand and Support
Authors: Fernemark Hanna , Skagerstrom Janna , Seing Ida , Ericsson Carin , Nilsen Per 
Published: October 2020

Abstract
Background: Digital consultation with primary care physicians via mobile telephone apps has been spreading rapidly in Sweden since 2014. Digital consultation allows remote working because physicians can work from home, outside their traditional primary care environment. Despite the spread of digital consultation in primary care, there is a lack of knowledge concerning how the new service affects physicians’ psychosocial work environment. Previous research has focused primarily on the patients’ point of view and the cost-effectiveness of digital consultation. Hence, there is a paucity of studies from the perspective of physicians, focusing on their psychosocial work environment. The aim of this study was to investigate primary care physicians’ perceived work demands, control over working processes, and social support when providing digital consultation to primary care patients.Methods: The study has a qualitative design, using semi-structured interviews conducted in Sweden in 2019. We used a purposeful sampling strategy to achieve a heterogeneous sample of physicians who represented a broad spectrum of experiences and perceptions. The interviews were conducted by video meeting, telephone, or a personal meeting, depending on what suited the participant best. The interview questions were informed by the Job Demand-Control-Support (JDCS) model, which was also used as the framework to analyze the data by categorizing the physicians’ perceptions and experiences into the three categories of the model (Demand, Control, Support), in the deductive analysis of the data.Results: Analysis of the data yielded 9 subcategories, which were mapped onto the 3 categories of the JDCS model. Overall, the participants saw numerous benefits with digital consultations, not only with regard to their own job situation but also for patients and the health care system in general even though they identified some shortcomings and risks with digital care.Conclusions: This study has demonstrated that physicians perceive working with digital consultation as flexible with a high grade of autonomy and reasonable to low demands. According to the participants, digital consultation is not something you can work with full time if medical skills and abilities are to be maintained and developed.
Development of a behaviour change workplace-based intervention to improve nurses’ eating and physical activity
Authors: Power Brian , Kiezebrink Kirsty , Allan Julia L , Campbell Marion K 
Published: October 2020

Abstract
Background: There is a critical need for an intervention to improve nurse’s eating and physical activity behaviours. As nurses spend a substantial proportion of their waking hours at work, concerted efforts to deliver such interventions in the workplace is growing. This study formed part of a multiphase programme of research that aimed to systematically develop an evidence-based and theory-informed workplace intervention to promote changes in eating and physical activity among nurses. Methods: The intervention was developed iteratively, in line with Medical Research Council complex intervention guidelines. It involved four activities; (1) identifying the evidence base; (2) understanding the determinants of nurses’ eating and physical activity behaviour change through theory-based qualitative interviews and survey; (3) identifying intervention options using the Behaviour Change Wheel; and (4) specifying intervention content and implementation options using a taxonomy of behaviour change techniques.Results: Data from 13 randomised controlled trials indicated that workplace-based behaviour change interventions targeted to this population are effective in changing behaviour. The evidence base was, however, limited in quantity and quality. Nurses’ beliefs about important factors determining their eating and physical activity behaviour were identified across 16 qualitative interviews and 245 survey responses and key determinants included: environmental context and resources; behavioural regulation; emotion; beliefs about consequences; knowledge and optimism. Based on these findings, 22 behaviour change techniques suitable for targeting the identified determinants were identified and combined into a potential workplace intervention.Conclusions: An evidence-based and theory-informed intervention tailored to the target population and setting has been explicitly conceptualised using a systematic approach. The proposed intervention addresses previous evidence gaps for the user population of nurses. Further to this, such an intervention, if implemented, has the potential to impact nurses’ eating and physical activity behaviours and in turn, the health of nurses and the quality of healthcare delivery.
Socioeconomic inequalities in hypertension in Kenya: A decomposition analysis of 2015 Kenya STEPwise survey on non-communicable diseases risk factors
Authors: Gatimu Samwel Maina , John Thomas Wiswa 
Published: October 2020

Abstract
Background: One in four Kenyans aged 18–69 years have raised blood pressure. Despite this high prevalence of hypertension and known association between socioeconomic status and hypertension, there is limited understanding of factors explaining inequalities in raised blood pressure in Kenya. Hence, we quantified the socioeconomic inequality in hypertension in Kenya and decomposed the determinants contributing to such inequality.Methods: We used data from the 2015 Kenya STEPwise survey for non-communicable diseases risk factors. We included 4,422 respondents aged 18–69 years. We estimated the socioeconomic inequality using the concentration index (C) and decomposed the C using Wagstaff decomposition analysis.Results: The overall concentration index of hypertension in Kenya was −0.08 (95% CI: −0.14, −0.02; p = 0.005), showing socioeconomic inequalities in hypertension disfavouring the poor population. About half (47.1%) of the pro-rich inequalities in hypertension was explained by body mass index while 26.7% by socioeconomic factors (wealth index (10.4%), education (9.3%) and paid employment (7.0%)) and 17.6% by sociodemographic factors (female gender (10.5%), age (4.3%) and marital status (0.6%)). Regional differences explained 7.1% of the estimated inequality with the Central region alone explaining 6.0% of the observed inequality. Our model explained 99.7% of the estimated socioeconomic inequality in hypertension in Kenya with a small non-explained part of the inequality (−0.0002).Conclusion: The present study shows substantial socioeconomic inequalities in hypertension in Kenya, mainly explained by metabolic risk factors (body mass index), individual health behaviours, and socioeconomic factors. Kenya needs gender- and equity-focused interventions to curb the rising burden of hypertension and inequalities in hypertension.
Nutritional Status of HIV-Positive Pregnant Women in Luanda, Angola
Authors: Santana Marli Stela , FILIPE Maura Eunice João 
Published: October 2020

Abstract
During pregnancy, maternal intake of nutrients and their nutritional status affects both mother and baby. Good nutritional status plays an important role for a healthy pregnancy, for this it is necessary that the pregnant woman have a healthy diet to assist in weight gain.Objective: To evaluate the pregestational and gestational nutritional status of HIV-positive women.Methods: This is a cross-sectional and descriptive study, conducted from August to November 2018 in which 171 HIV-positive pregnant women were selected at random, in order of arrival and submitted to nutritional assessment through the Global Subjective Evaluation, whose data collected, were analyzed using EpiInfo software version 7.2.Results: From the main results found it was observed the presence of maternal nutritional eutrophic, considering the pre-gestational Body Mass Index (BMI) of 107 (62.56%), and the gestational BMI of 94 (54.97%). It was found 31(18.12%) of pre-gestational overweight and 54 (28.07%) of overweight during pregnancy, and it was also observed that 12 (7%) of pregnant women were obese before pregnancy and 15 (15.28%) became obese during pregnancy. A significant association was found between pregestational BMI, height (p˂0.0001), gestational BMI, current weight (p˂0.0003), brachial perimeter (p˂0.002), and uterine height (p˂0.005).Conclusion: The results of this study indicate the need to develop nutritional care programs for HIV-positive women, in order to ensure an adequacy of their nutritional status.
Older age and multi-joint external fixator are two risk factors of complications in ulnar lengthening in children with hereditary multiple exostosis
Authors: Zheng Chao , Han Huanli , Cao Yujiang 
Published: October 2020

Abstract
Objectives:
Hereditary multiple exostosis (HME) often involves forearm deformities. The aim of this study was to present the clinical results of 37 children who underwent ulnar lengthening with two different types of unilateral external fixators, and to investigate the risk factors of complications.
Methods:
We evaluated 37 children with forearm deformities caused by HME treated in our hospital from January 2008 to July 2019. The surgical procedures included resection of exostosis, osteotomy of the ulna, and gradual lengthening of the ulna with a single arm external fixator. According to the type of external fixator they received, the children were divided into two groups: group A received monorail fixators, and group B received multi-joint fixators. Radiographic and functional parameters were assessed. Complications were recorded.
Results:
All patients were followed up for an average of 4.6 years (3.0 to 6.5). In both group A and group B, the ulna shortening (US), radial articular angle (RAA), carpal slip (CS), elbow flexion, forearm pronation, supination, and Mayo Elbow Performance Score (MEPS) values improved significantly from preoperatively to postoperatively ( p < 0.05). However, ulnar deviation was observed in 4 cases in group B and no cases in group A. According to logistic regression, the difference was only related to age ( p <0.05) and the type of external fixator ( p <0.05).
Conclusions:
Ulnar lengthening with unilateral external fixation is a safe and effective procedure for the treatment of HME. Regarding complications, deviation of the ulna axis was more likely to occur in older children with multi-joint external fixators.
Effect of a natural plant ingredient — Pulsatilla saponin B4 on clinical mastitis and serum inflammatory indices in dairy cows
Authors: Shen Liuhong , Qian Bolin , You Liuchao , Zhang Yue , Shen Yu , Lv Shangkui , Xiao Jinbang , Su Zhetong , Dong Ke , Zong Xiaolan , Yu Shumin , Cao Suizhong , Yang Shilin , Feng Yulin 
Published: October 2020

Abstract
Background: Bovine mastitis is an inflammatory reaction of the breast caused by pathogenic bacteria infection or breast injury, which affect milk yield and quality and poses severe threat to the health of dairy cows. Pulsatilla chinensis has antibacterial, anti-inflammatory, and immune enhancing effects, etc. However, there was no research about the therapeutic effect of it towards the treatment of cow mastitis. In the study, twelve healthy cows were selected as the control group (group A), and 36 cows with mastitis were equally and randomly divided into group B, C and D. Group A didn’t accept treatment, while group B, C and D were treated with 15, 30 and 60 mL Pulsatilla saponin B4 (a purified extract form Pulsatilla chinensis) injection by brachiocephalicus intramuscular injection once a day for 4-6 day and the optimal dose was selected from them. Then, we investigated the effect of this extract on the clearance rates of pathogenic bacteria, the regulation of somatic cell count (SCC) and inflammatory factors the in appropriate dose group.Results: Pulsatilla saponin B4 was effective in all test groups and showed a dose-effect relationship. The extract had inhibitory effects on Streptococcus agalactiae, Streptococcus dysenteriae, Klebsiella species, Mycoplasma bovis, Escherichia coli and Staphylococcus aureus. Group C cured more cows than group B and D during the 6 days of treatment and was determined as the optimal dose group. The milk SCC, serum haptoglobin (HP), prostaglandin E2 (PGE2), interleukin-1 alpha (IL-1α), interleukin-1 beta (IL-1β), interleukin-2 (IL-2), interleukin-8 (IL-8), interleukin-10 (IL-10) and tumour necrosis factor alpha (TNF-α), interleukin-4 (IL-4) and leukotriene B4 (LTB4) in Group C were significantly higher than those of healthy cows (P < 0.05) on the first day but had no significant difference with group A after treatment. Conclusion: 30 mL Pulsatilla saponin B4 applied through intramuscular injection once a day for 4-6 days leaded to the significant amelioration of bacterial infection, SCC and levels of serum inflammatory factors in cows with clinical mastitis.
Current Perception Threshold Testing in Chronic Ankle Instability
Authors: Zhang Ran , Zhang Xi , Chen Yaping , Song Weiqun 
Published: October 2020

Abstract
Background: Damage to sensory input is one of the pathologies underlying chronic ankle instability (CAI). Therefore, it is necessary to evaluate the sensory function of patients with CAI. This study aims to quantitatively evaluate sensory nerve function in patients with CAI and healthy controls using current perception threshold (CPT) measurements.Methods: Fifty-nine subjects with CAI and 30 healthy control individuals participated in this study. CPT values at the anterior talofibular ligament region were tested on the injured and uninjured sides in CAI patients and on a random side in the healthy control group.Results: There were no significant differences in age, gender, height, weight or BMI between the CAI and healthy control groups. The CPT values did not show significant gender differences. The CPT values were not significantly correlated with age or BMI. Compared to the control group (250 Hz: 24.32±9.28, 5 Hz: 6.87±1.56), the CAI group had significantly higher CPT values on the injured (250 Hz: 42.83±28.49, 5 Hz: 23.43±18.53) and uninjured sides (250 Hz: 38.62±19.98, 5 Hz: 18.84±14.21) under 250 Hz and 5 Hz electrical stimuli (p<0.01). No significant difference was observed under 2000 Hz stimuli. There were correlations among CPT values at different frequencies (p<0.01).Conclusion: This study revealed increased sensory thresholds in injured and uninjured ankles of 250 Hz- and 5 Hz-related sensory nerve fibers among patients with CAI. The bilateral change in sensory threshold may indicate a central sensory modulation process.Level of Evidence: Level III, case-control study.
Epidemiological Survey and Screening Strategy for Dengue Virus in Blood Donors from Yunnan Province
Authors: LI LING , LI YING , Lu Shaofang , Dong Jing , Xu Haixia , Zhang Qian , Weng Rong , Yin Yundi , He Rui , Fang Peng , Shi Hua , Yu Yinghan , Wu Ji , Liu Zhong , Hess John R. 
Published: October 2020

Abstract
BACKGROUNDDengue virus (DENV) can be transmitted through blood transfusion. DENV was not screened regularly in Xishuangbanna blood center. This study was conducted in Xishuangbanna blood center with an attempt to develop DENV screening strategies in one of China’s high-incidence areas.METHODSBlood samples were collected randomly between June 2019 and August 2019. These samples were first screened for anti-DENV IgG and IgM using enzyme-linked immunosorbent assay (ELISA). All reactive samples and some randomly-chosen non-reactive samples were used to detect DENV RNAs using real-time polymerase-chain-reaction (RT-PCR) assay. After RT-PCR assay, these samples were further tested for soluble nonstructural protein 1 (NS1) using the colloidal gold method. The demographic data of donors were collected.RESULTSA total of 2,254 donor samples were collected and tested for anti-DENV IgG and IgM by ELISA between June 2019 and August 2019. ELISA testing revealed that 598 donor samples were anti-DENV IgG and/or IgM reactive, with a serological prevalence of 26.53%. Among all the donor samples, 26 were RT-PCR positive and/or NS1 positive. Moreover, there were significant differences in the prevalence of DENV in terms of occupation (P=0.001), education(P<0.001) and ethnicity (P=0.026).CONCLUSIONThe prevalence of DENV in Xishuangbanna Blood Center was higher than most other blood centers that have implemented DENV donor screening. Our study provides the first-hand data about the prevalence of DENV and allows the development of a screening strategy for clinical use.
Multi-omics examination of Q fever fatigue syndrome identifies similarities with chronic fatigue syndrome
Authors: Raijmakers Ruud , Roerink Megan E. , Jansen Anne F.M. , Keijmel Stephan P. , Gacesa Ranko , Li Yang , Joosten Leo A.B. , Meer Jos W.M. van der , Netea Mihai G. , Bleeker-Rovers Chantal P. , Xu Cheng-Jian 
Published: October 2020

Abstract
Background: Q fever fatigue syndrome (QFS) is characterised by a state of prolonged fatigue that is seen in 20% of acute Q fever infections and has major health-related consequences. The molecular mechanisms underlying QFS are largely unclear. In order to better understand its pathogenesis, we applied a multi-omics approach to study the patterns of the gut microbiome, blood metabolome, and inflammatory proteome of QFS patients, and compared these with those of chronic fatigue syndrome (CFS) patients and healthy controls (HC). Methods: The study population consisted of 31 QFS patients, 50 CFS patients, and 72 HC. All subjects were matched for age, gender, and general geographical region (South-East part of the Netherlands). The gut microbiome composition was assessed by Metagenomic sequencing using the Illumina HiSeq platform. A total of 92 circulating inflammatory markers were measured using Proximity Extension Essay and 1607 metabolic features were assessed with a high-throughput non-targeted metabolomics approach. Results: Inflammatory markers, including 4E-BP1 (P = 9.60-16 and 1.41-7) and MMP-1 (P = 7.09-9 and 3.51-9), are significantly more expressed in both QFS and CFS patients compared to HC. Blood metabolite profiles show significant differences when comparing QFS (319 metabolites) and CFS (441 metabolites) patients to HC, and are significantly enriched in pathways like sphingolipid (P = 0.0256 and 0.0033) metabolism. When comparing QFS to CFS patients, almost no significant differences in metabolome were found. Comparison of microbiome taxonomy of QFS and CFS patients with that of HC, shows both in- and decreases in abundancies in Bacteroidetes (with emphasis on Bacteroides and Alistiples spp.), and Firmicutes and Actinobacteria (with emphasis on Ruminococcus and Bifidobacterium spp.). When we compare QFS patients to CFS patients, there is a striking resemblance and hardly any significant differences in microbiome taxonomy are found.Conclusions: We show that QFS and CFS patients are similar across three different omics layers and 4E-BP1 and MMP-1 have the potential to distinguish QFS and CFS patients from HC.
Analysis and Prediction of COVID-19 Pandemic in Bangladesh by using Long short-term memory network (LSTM) and Adaptive neuro fuzzy inference system(ANFIS)
Authors: Chowdhury Anjir Ahmed , Hasan Khandaker Tabin , Hoque Khadija Kubra Shahjalal 
Published: October 2020

Abstract
Objectives: The dangerously contagious virus named SARS-CoV-2 has hit the world hard that has locked downed billion people in their homes for stopping fur- ther spread. All the researchers and scientists in various fields are working around the clock to come up with a vaccine and prevention methods to save the world from this invisible pathogen. However, reliable prediction of the epidemic may help contain the contagion until cure becomes available. The machine learning techniques is one of the frontier in predicting the future trend and behavior of this outbreak. Our research is focused on finding a suitable machine learning model that can pre- dict on small dataset with higher accuracy.Methods: In this research, we have used the Adap- tive Neuro-Fuzzy Inference System (ANFIS) and the long short-term memory[LSTM] to foresee the newly infected cases in Bangladesh. We have compared both the results of the experiments and it can be forenamed that LSTM has shown more satisfactory results.Results: Upon study and testing on several models, we have showed that LSTM works better on scenario based model for Bangladesh with MAPE 4.51, RMSE 6.55 and Correlation Coefficient 0.75.Conclusion: This study is expected to shade light on Covid-19 prediction models for researchers working with machine learning techniques and help avoid proven failures specially for small imprecise dataset.