bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Implications of Jump Distance on Landing Error Scoring System Scores
Authors: Hanzlíková Ivana , Hébert-Losier Kim 
Published: November 2020

Abstract
Context: The Landing Error Scoring System (LESS) screens for risk of non-contact Anterior Cruciate Ligament injury. The LESS requires individuals to jump forward from a 30-cm box to a distance of 50% of their body height. However, different landing distances have been used in the scientific literature.
Objective: To examine whether landing distance influences LESS outcomes.
Design: Cross-sectional.
Setting: Laboratory.
Participants: Seventy young active individuals (34 males, 36 females).
Intervention: Participants performed 3 × 30-cm jump-landing tasks under two landing conditions in randomized order: (1) 50% of body height (d50%), (2) self-selected distance (dss).
Main outcome measures: Mean LESS scores, proportions of individuals categorized at high (LESS ≥ 5 errors) and low (LESS &lt; 5 errors) injury risk, and landing distances were compared between conditions using Generalized Estimating Equations. Consistency of risk categorization was examined using odds ratios (OR) and McNemar's tests. McNemar's and Wilcoxon signed rank tests were used to compare occurrence of specific LESS errors.
Results: Participants landed significantly closer to the box under the dss condition (difference: −23.28 [−20.73 to −25.81]%, p &lt; 0.001). Group mean LESS scores (difference: −0.01 [−0.59 to 0.57] error, p = 0.969) and risk categorization (OR: 0.94 [0.47 to 1.88], p = 0.859) were similar between conditions. However, individual-level risk categorization was inconsistent in 33% of participants, as was the occurrence of specific errors.
Conclusion: Using dss during LESS might lead to different LESS errors and risk categorization at an individual level compared to d50%. Given that individual LESS scores are of primary interest in clinical and sport settings, and the injury-risk threshold has not been validated for dss, the use of the original LESS protocol is recommended. When only group mean LESS scores or proportions of at risk individuals is of interest, using dss is possible to facilitate large cohort testing.
CXCR4 and RIF1 overexpression induces resistance of epithelial ovarian cancer to cisplatin-based chemotherapy
Authors: Sad Lamiss Mohamed Abd Elaziz , Mohamed Dareen Abdelaziz , Elanwar Noha M , Elkady Assama 
Published: November 2020

Introduction:
The chemoresistance of epithelial ovarian cancer (EOC) is a major problem. Thus, the search for novel biomarkers associated with cisplatin sensitivity is overwhelming. Previous studies have shown that CXC chemokine receptor 4 (CXCR4) is associated with tumor growth, angiogenesis, and distant metastases, and replication timing regulatory factor 1 (RIF1) is responsible for the repair of double-strand DNA breaks. This study, thus, aimed to identify the correlation between CXCR4 and RIF1 overexpression and cisplatin sensitivity in EOC.

Materials and Methods:
Fifty-five EOC patients were recruited to assess the chemosensitivity of EOC to cisplatin-based chemotherapy at the Oncology Department in Tanta University Hospitals, Egypt.

Results:
The results showed that patients with a higher CXCR4 and RIF1 expression exhibited a significantly lower chemosensitivity, worse overall survival, and poorer progression-free survival. The only prognostic associated with overall survival was CXCR4.

Conclusion:
Our study showed that CXCR4 and RIF1expression levels are not associated only with poor prognostic features of epithelial ovarian cancer but also with its chemoresistance to cisplatin, and consequently, with worse overall survival and progression free survival.
Erratum: Limiting properties of the distribution of primes in an arbitrarily large number of residue classes
Authors: Devin Lucile 
Published: November 2020

AbstractAs pointed out by Alexandre Bailleul, the paper mentioned in the title contains a mistake in Theorem 2.2. The hypothesis on the linear relation of the almost periods is not sufficient. In this note, we fix the problem and its minor consequences on other results in the same paper.
Isap v2.0
Authors: Dobraunig Christoph , Eichlseder Maria , Mangard Stefan , Mendel Florian , Mennink Bart , Primas Robert , Unterluggauer Thomas 
Published: November 2020

We specify Isap v2.0, a lightweight permutation-based authenticated encryption algorithm that is designed to ease protection against side-channel and fault attacks. This design is an improved version of the previously published Isap v1.0, and offers increased protection against implementation attacks as well as more efficient implementations. Isap v2.0 is a candidate in NIST’s LightWeight Cryptography (LWC) project, which aims to identify and standardize authenticated ciphers that are well-suited for applications in constrained environments. We provide a self-contained specification of the new Isap v2.0 mode and discuss its design rationale. We formally prove the security of the Isap v2.0 mode in the leakage-resilient setting. Finally, in an extensive implementation overview, we show that Isap v2.0 can be implemented securely with very low area requirements.
https://isap.iaik.tugraz.at
A survey of perioperative complications with Clavien-Dindo classification: a cross-sectional study
Authors: Muhammad Talha Khan  , Talha Akhtar  , Muhammad Atif Yasin  , Noman Ahmed Chaudhary  , Abdullah Sadiq  , Ahsan Tameez ud din  
Published: November 2020

Abstract
Objectives: To determine the incidence of complications in elective surgeries and to grade them according to the Clavien-Dindo Classification System.
Method: The cross-sectional study was conducted in the General Surgery Operation Theatre of Holy Family Hospital, Rawalpindi, Pakistan, from February to April 2018, and comprised patients undergoing elective surgeries. Age, gender, region of surgery, type and grade of complications, were recorded using Clavien-Dindo Classification proforma. Data was analysed using SPSS 23.
Results: Of the total 212 patients, 36(16.9%) had some complication. There were significantly more complications in people aged 40 years or above compared to those <40 years (p<0.05). Of the total surgeries, 126(59.43%) were in the abdomino-pelvic region.
Conclusion: Peri-operative complications were found to be significantly related with age of the patient and the type of surgery.
Key Words: Classification, Peri-operative procedures, Continuous...
Rudolf Malter e o pessimismo crítico schopenhaueriano
Authors: Durante Felipe dos Santos 
Published: November 2020

Este artigo tem por objetivo, a partir da leitura do célebre livro de Rudolf Malter – O pensamento único: introdução à filosofia de Arthur Schopenhauer (Der Eine Gedanke: Hinführung zur Philosophie Arthur Schopenhauers), em especial da seção intitulada Característica conclusiva: Pessimismo – um conceito crítico (Abschließende Charakteristik: Pessimismus – ein kritischer Begriff ) –, apresentar a hipótese hermenêutica de um dos mais eminentes interpretes da filosofia schopenhaueriana, a qual versa sobre o pessimismo enquanto conceito crítico, e que pode ser entendida como um dos pontos de sustentação para a justificativa de interpretação da filosofia schopenhaueriana a partir de um viés soteriológico.
El lápiz color piel y el sufrimiento racial en la socialización de los infantes de la negritud
Authors: Mena Garcia Maria Isabel 
Published: November 2020

En diferentes escenarios ha sido constante la idea que Colombia, no es solo es un país multiétnico, plurilinguístico sino también poliracial. Los dos primeros calificativos están más presentes en la vida nacional, mientras que la imagen de varias razas, representa en el mejor de los casos un pánico social difícil de nombrar, fácil de polemizar al negar o admitir su existencia. Particularmente, donde la revelación de los colores de la piel, provoca mayor sensibilidad es en la escuela, por ello este avance, se suma a la corriente de estudios que se ocupan de las consecuencias de la raza en la vida de los infantes escolarizados. Para delimitar el alcance de este artículo se precisa que éste, corresponde a los resultados preliminares de una tesis doctoral en curso cuyo tema central es la identidad racial de niños y niñas negros, para situar este debate, se pregunta ¿Con que colores pinta la niñez de la negritud, su color de piel y fenotipo? En términos metodológicos, se escogió el método cualitativo que a través de talleres sobre el dibujo del cuerpo posibilitara la participación protagónica de los infantes, para a partir de esas fuentes, provocar nuevas interrogaciones al sujeto niño negro, cuyos conocimientos en los estudios de la infancia, siguen brillando por su ausencia. Las respuestas iniciales señalan que estos dibujantes, no se pintan mayoritariamente con colores distintos al color piel o rosado, tan común en las cajas de colores infantiles, situación que corrobora hallazgos de hace décadas en torno a una conciencia racial, que muestra confusiones por parte de los renacientes de la negritud.
Long-term follow-up results of patients diagnosed with nonspecific pleuritis by video-assisted thoracoscopic surgery biopsy
Authors: Agca Meltem , Yildiz Reyhan , Akyil Fatma T. , Sen Aycim , Kosif Aysun , Akyil Mustafa , Sevim Tulin 
Published: November 2020

IntroductionNon-specific pleuritis (NSP) is a fibrinous or inflammatory pleurisy that is not attributable to a benign or malign etiology. The long-term follow-up results of patients diagnosed with NSP following video-
assisted thoracoscopic surgery (VATS) were investigated in this study.Material and methodsThis investigation focused on 593 patients with exudative pleural effusion who underwent VATS between 2011 and 2014. Of the 137 patients diagnosed with NSP, a total of 39 patients were excluded from the study.ResultsOut of the 98 patients, 78 were male (80%) with their mean age being 52.2 ±15.9 years. The mean follow-up period was 1919 ±744 days. Of these patients, 70 (71.4%) had no specific diagnosis, while 28 patients (28.6%) did have specific diagnoses. Malignancy was detected in seven (7.1%) of those with specific diagnoses, with most of the diagnoses of malignancy detected within the first 36 months. Malignant diseases included mesothelioma (n = 2), lung cancer (n = 2), chronic lymphocytic leukemia (n = 1), soft tissue sarcoma (n = 1), and multiple myeloma (n = 1). Chest radiographs of malignant patients showed that statistically significantly larger amounts of fluid (40% vs. 6.9%, p = 0.026), pleural plaque (20% vs. 1.1%, p = 0.020) and nodules (20% vs. 7.7%, p = 0.020) were detected compared to patients with a benign course.ConclusionsMost patients diagnosed with NSP after VATS had a benign disease course. There was a probability of malignancy, although it was low. Mesothelioma and other malignancies could be seen within the first 36 months after the biopsy. Apart from mesothelioma, other malignancies should also be considered, and further follow-up recommended for patients with a large amount of fluid, plaque and nodules found in the initial VATS images.
A novel homozygous ALMS1 protein truncation
mutation (c.2938dupA) revealed variable clinical
expression among Saudi Alström syndrome patients
Authors: Bdier Amnah Yousuf , Al-Qahtani Faten Abdullah , Kumar Verma Prashant , Alshoaibi Naeem Abdulmoneem , Mohammed Alrayes Nuha , Shaik Noor Ahmad , Foo Roger Sik Yin , Bhuiyan Zahurul Alam , Al-Aama Jumana Y. 
Published: November 2020

IntroductionAlström syndrome, ALMS (OMIM 203800) is a rare multi-systemic disease. The characteristic clinical features include blindness due to progressive cone-rod dystrophy, sensorineural hearing loss, type 2 diabetes mellitus, dilated cardiomyopathy, and childhood obesity. The aim of this study was to identify the genetic cause of Alström syndrome in patients who presented with variable clinical characteristics.Material and methodsClinical phenotyping and whole exome sequencing were performed in Saudi Alström syndrome patients. The Sanger sequencing was done to ascertain the segregation of Alström syndrome causative mutation in the family members. The rare prevalence of this mutation was further established by sequencing an additional 100 healthy Saudi controls.ResultsWhole exome sequencing analysis revealed that Alström syndrome patients have inherited a novel homozygous protein truncating mutation (c.2938dupA) in the ALMS1 gene segregated in an autosomal recessive fashion. This variant was absent in healthy controls. Genotype-phenotype analysis showed its interesting association with intra-familial clinical variability with regards to vision abnormalities, age at onset of dilated cardiomyopathy (DCM), obesity and hearing loss symptoms in the Alström syndrome patients.ConclusionsOur findings indicate that the atypical presentation of Alström syndrome, even within siblings, could sometimes lead to clinical misdiagnosis. Hence, the present study emphasizes the utility of exome sequencing to support the clinical diagnosis of Alström syndrome patients.
The effect of the spread of the new COVID-19 on the psychological and social adaptation of families of persons with disabilities in the Kingdom of Saudi Arabia
Authors: Khasawneh Mohammad 
Published: November 2020

BackgroundHelping families of persons with disabilities in times of the spread of COVID-19 is a major step to ensure their social and psychological adaptation. This call comes from the fact that from a health perspective, persons with disabilities have less immunity and are more vulnerable to deceases and infections. Many families of persons with disabilities have also expressed their concerns regarding the safety of their disabled member/s. Therefore, this study aimed to identify the impact of the new COVID-19 on the psychological and social adjustment of fam-ilies of persons with disabilities in the Kingdom of Saudi Arabia.Participants and procedureThe sample of the study was chosen randomly from the Asir region. The sample consisted of any member of the families of persons with disabilities (parents and siblings). Participants responded to a questionnaire, which was sent electronically via WhatsApp to the families of persons with disabilities. The questionnaire gathered demographic information about the disabled member from the family (age and level of disability). The ques-tionnaire underwent statistical treatment to extract data for analysis.ResultsThe results showed less ability for families of persons with disabilities to adapt psychologically and socially to the spread of COVID-19. The findings revealed the existence of fundamental differences in the levels of psy-chological and social adaptation among these families due to the level of disability of their member and due to the variable of age, and in favor of the age group of 11-15 years. The study recommended providing safe methods of communication with families of persons with disabilities to reduce the feeling of psychological iso-lation and loneliness as much as possible during the quarantine or curfew periods.ConclusionsThis study explored the levels of psychological and social adaptation of families of persons with disabilities in the time of COVID-19. The spread of the virus created a crisis in different counties and millions of people were infected. Persons with disabilities are among the categories affected most by the infection of the virus due to their weak immunity and their health problems. Therefore, response plans need to take measures that cover the needs of persons with disabilities and their families.
A comparative evaluation of the Eustachian tube cartilage between healthy and diseased ears using a 3 Tesla MRI
Authors: Aydın Nevin , Saylısoy Suzan , Adapınar Baki , Arslantas Didem 
Published: November 2020

IntroductionThe purpose of this study was to prospectively assess the Eustachian tube (ET) cartilage using 3 Tesla (3T) magnetic resonance imaging (MRI) and compare the results between healthy ears and those with a middle ear disease.Material and methodsThe study included 56 ears with a middle ear disease as the patient group and 100 ears without a middle ear disease as the control group. The patients’ age ranged from 18 to 65 years. The axial three-dimensional (3D) multiple echo recombined gradient echo (MERGE) sequence and oblique parasagittal planes were obtained. Visualisation of the ET cartilage was assessed on the MR images using a three-point numerical rating score. In the axial plane, the ET lumen’s diameter was measured from the mid-portion of the cartilage.ResultsThere was no significant difference between the patient group and the control group according to patients’ age and gender, and the medial laminal thickness of the ET cartilage. In the patient group, the diameter of the ET cartilage was significantly smaller than in the control group. The ET lumen diameter was significantly lower according to each of the three scoring systems.Conclusions3T MRI provides an evaluation of the ET cartilage and isthmus level, which are small but important anatomical localisations and surgical landmarks. MR imaging has the potential to provide essential information on ET prior to new surgical treatments, such as balloon dilation for middle ear diseases.
Correlation of texture feature analysis with bone marrow infiltration in initial staging of patients with lymphoma using 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography
Authors: Kenawy Mahmoud A. , Khalil Magdy M. , Abdelgawad Mahmoud H. , El-Bahnasawy H. H. 
Published: November 2020

IntroductionTo explore whether radiomic features of fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomo­graphy–computed tomography (PET/CT) has association with bone marrow infiltration (BMI) in comparison to other conventional PET metrics.Material and methodsForty-four patients (with pathologically proven lymphoma disease) underwent staging 18F-FDG PET/CT scan. Primary tumour was semi-automatically or manually segmented with a threshold standardised uptake value (SUV) of 3. A total of 73 features were extracted from eight different textures. Spearman correlation was used to test the correlation of features with conventional quantitative metrics such as SUV, metabolic tumour volume, and total lesion glycolysis. Specificity and sensitivity (including 95% confidence intervals [CI]) for each of the studied parameters were derived using receiver operative characteristic (ROC) curves. Univariate and multivariate analyses were used to identify independent predictors associated with BMI.ResultsCorrelation between conventional PET metrics and features ranged between 0.50 and 0.97 for positive correlation (33 significant association features) and ranged from –0.52 to –0.97 for inverse correlation (three significant association features) for both strong and moderate correlations. Analysis of ROC curves showed that high-intensity long-run emphasis 4 bin, high-intensity large zone emphasis 64 bin, long-run emphasis (LRE) 64 bin, large-zone emphasis 64 bin, max spectrum 8 bin, busyness 64 bin, and code similarity 32 and 64 bin were significant discriminators of BMI among other features (area under curve > 0.682, p < 0.05). Univariate analyses of texture features showed that code similarity and long-run emphasis (both 64 bin) were significant predictors of bone marrow involvement. Multivariate analyses revealed that LRE (64 bin, p = 0.031) with an odds ratio of 1.022 and 95% CI of (1.002–1.043) were independent variables for bone marrow involvement.Conclusions18F-FDG PET/CT radiomic features are synergistic to visual assessment of BMI in patients diagnosed with lymphoma using 18F-FDG PET/CT. Further assessment of long-run emphasis is highly warranted.
Analysis of a Telescoped Orogenic Gold System: Insights from the Fosterville Deposit
Authors: Voisey Christopher R. , Tomkins Andrew G. , Xing Yanlu 
Published: November 2020

Abstract
The Fosterville gold (Au) deposit is hosted in the Bendigo zone within the western Lachlan orogen, southeast Australia, and contains three distinct mineralization styles: (1) refractory Au in fine-grained arsenopyrite and arsenian pyrite disseminated throughout metasedimentary rocks near brittle faults, (2) visible Au hosted in fault-controlled quartz-carbonate veins associated with stibnite mineralization, and (3) vein-hosted visible Au with little or no associated stibnite. Refractory Au mineralization is found throughout the deposit, whereas visible Au ± stibnite occurs deeper in the system (&gt;800-m depth from surface). Thus, Fosterville provides a unique opportunity to study a telescoped orogenic Au system that changes mineralization style as a function of depth. Microscopy, neutron tomography, nanoscale secondary ion mass spectrometry, and field observations have been conducted to investigate mineralogical and structural controls on the various styles of Au mineralization. These observations are used as the foundation for reactive mass transport geochemical modeling using HCh software. Results are considered in the context of an evolving mineral system over the formation history of the deposit, and relative timing of mineralization is inferred. Two alternatives for the genesis of such a system include the following: (1) metal deposition was controlled by ongoing physicochemical changes at a very shallow level in the crust in one evolving mineralization stage or (2) two or three deposits formed in the same location, with each different style of mineralization representing a separate period of fluid infiltration, each potentially tens of millions of years apart. Based on careful observations, microanalysis, and thermodynamic modeling, we suggest that the latter is more likely. Therefore, we suggest that Fosterville is to be recognized as a telescoped orogenic Au system, where relatively high temperature mineralization and alteration assemblages were overprinted vertically by later, lower-temperature assemblages.
Nuclear microsatellites reveal population genetic structuring and fine-scale pattern of hybridization in the Japanese mantis shrimpOratosquilla oratoria
Authors: Cheng Jiao , Zhang Nan , Sha Zhongli 
Published: November 2020

The interplay between historical and contemporary processes can produce complex patterns of genetic differentiation in the marine realm. Recent mitochondrial and nuclear sequence analyses revealed cryptic speciation in the Japanese mantis shrimpOratosquilla oratoria. Herein, we applied nuclear microsatellite markers to examine patterns and causes of genetic differentiation in this morphotaxon. Population structure analyses revealed two genetically divergent and geographically structured clades inO. oratoria, one dominating the temperate zone of the Northwestern (NW) Pacific and the other occurring in the subtropical and tropical waters where are influenced by the Kuroshio Current. Two sympatric zones, one around the Changjiang Estuary in China coast and the other in the northern Japan Sea, were demonstrated to be hybrid zones where introgressive hybridization occurred asymmetrically. The interaction between historical climate shifts and contemporary factors (e.g., freshwater discharge, temperature gradient and isolation by distance) may contribute to the present-day genetic architecture in the Japanese mantis shrimp. Range shift induced by climate changes and oceanographic factors may promote hybridization and gene flow between theO. oratoriacomplex. Our results provide insights into the interacting mechanisms that give rise to diversification and speciation of coastal species in the NW Pacific.