bluuebunny/crossref_metadata_2025_split huggingface dataset:
De la naissance d’un duo à la constitution d’un système thérapeutique : le vécu expérientiel partagé comme vecteur de coévolution
Authors: Deltell Marion , Pujol Éloïse 
Published: November 2019

Cet article décrit comment de façon synchronisée et dans un processus de coévolution se sont réorganisées les interactions dans une famille et au sein d’un couple thérapeutique naissant. Nous souhaitons mettre en avant la notion de « vécu expérientiel partagé » et l’importance d’un travail au niveau sensori-moteur pour libérer l’imaginaire et le conceptuel. Suite à l’atelier proposé lors des 13 es Journées francophones de thérapie familiale de Lyon, nous voulons également témoigner de la poursuite de cette expérience partagée, qui a pu se prolonger grâce à l’apport des résonances des participants. En conclusion, nous souhaitons ouvrir des pistes de réflexion sur les apports de la sculpture en supervision et notamment comme outil de coévolution pour le couple thérapeutique lui-même.
Exploration of Factors Influencing Nurse Competence Through Nursing Profile Analysis
Authors: Jing Weihua , Zhang Xianying , Chi Rongxiang , Sun Xiufang , Lv Shuguang 
Published: November 2019

Background:
Nurse competence is a combination of knowledge, performance, skills, and attitudes that are required in fulfilling one's role as a nurse. So far, few comprehensive studies have explored the influencing factors of nurse competence.

Method:
The competence levels of 160 RNs in a Chinese hospital were evaluated using a questionnaire method, and the relationship between competence results and nursing characteristics was analyzed.

Results:
The competence of participating nurses was at a medium level. Among all the characteristics, education and staffing levels were two main factors influencing nurse competence.

Conclusion:

Quantity of nurses and quality of nursing service are two main issues facing the modern nursing system. The findings from this study provide useful information and suggestions on how to improve nurse competence to nurse industry personnel, including nurses, nursing employers, educators, and students.

[
J Contin Educ Nurs
. 2019;50(12):572–580.]
Splenic Red Pulp Macrophages Cross-Prime Early Effector CTL That Provide Rapid Defense against Viral Infections
Authors: Enders Marika , Franken Lars , Philipp Marie-Sophie , Kessler Nina , Baumgart Ann-Kathrin , Eichler Melanie , Wiertz Emmanuel J. H. , Garbi Natalio , Kurts Christian 
Published: November 2019

Abstract
Cross-presentation allows dendritic cells (DCs) to present peptides derived from endocytosed Ags on MHC class I molecules, which is important for activating CTL against viral infections and tumors. Type 1 classical DCs (cDC1), which depend on the transcription factor Batf3, are considered the main cross-presenting cells. In this study, we report that soluble Ags are efficiently cross-presented also by transcription factor SpiC-dependent red pulp macrophages (RPM) of the spleen. In contrast to cDC1, RPM used the mannose receptor for Ag uptake and employed the proteasome- and TAP-dependent cytosolic cross-presentation pathway, previously shown to be used in vitro by bone marrow–derived DCs. In an in vivo vaccination model, both cDC1 and RPM cross-primed CTL efficiently but with distinct kinetics. Within a few days, RPM induced very early effector CTL of a distinct phenotype (Ly6A/E+ Ly6C(+) KLRG1− CD127− CX3CR1− Grz-B+). In an adenoviral infection model, such CTL contained the early viral spread, whereas cDC1 induced short-lived effector CTL that eventually cleared the virus. RPM-induced early effector CTL also contributed to the endogenous antiviral response but not to CTL memory generation. In conclusion, RPM can contribute to antiviral immunity by generating a rapid CTL defense force that contains the virus until cDC1-induced CTL are available to eliminate it. This function can be harnessed for improving vaccination strategies aimed at inducing CTL.
Tumor Microenvironment following Gemcitabine Treatment Favors Differentiation of Immunosuppressive Ly6Chigh Myeloid Cells
Authors: Wu Caijun , Tan Xiaobin , Hu Xiaoling , Zhou Mingqian , Yan Jun , Ding Chuanlin 
Published: November 2019

Abstract
Regulation of myeloid-derived suppressor cells (MDSC) by ongoing inflammation following repeated chemotherapy remain elusive. In this study, we show that a multidose clinical regimen of gemcitabine (GEM) treatment enhances the immunosuppressive function of monocytic MDSC (M-MDSC), although tumor development is delayed in E0771 tumor-bearing mice. Accordingly, effector IFN-γ–producing CD4 and CD8 T cells are significantly decreased in the tumor microenvironment (TME) of GEM-treated mice. The conditioned medium of GEM-treated tumor cells enhances differentiation of mouse bone marrow cells and human PBMC into immunosuppressive M-MDSC. Cytokine profiling of GEM-treated tumor cells identifies GM-CSF as one of the most differentially expressed cytokines. Blockade or knockdown of GM-CSF can partially reduce immunosuppression of Ly6Chigh cells induced by GEM–conditioned medium. Knockdown of GM-CSF in tumor cells also delays tumor progression with decreased accumulation of M-MDSC in the TME. Mechanistically, enhanced production of reactive oxygen species and activation of NF-κB are observed in GEM-treated tumor cells. Treatment with the mitochondrial-targeted antioxidant and inhibitor of NF-κB signaling can abrogate GEM-induced hyperexpression of GM-CSF in E0771 cells. In addition, the phagocytic clearance of apoptotic tumor cells (efferocytosis) enhances the immunosuppressive function of bone marrow Ly6Chigh myeloid cells. Further, GEM treatment results in metabolic changes in residual tumor cells, leading to the resistance to T cell–mediated killing. Together, our results define an undesired effect of repeated GEM treatment promoting immunosuppression in TME via upregulation of GM-CSF and efferocytosis as well as deregulation of lipid metabolism in residual tumor cells.
Deep Learning
Authors: Kelleher John D. 
Published: November 2019

An accessible introduction to the artificial intelligence technology that enables computer vision, speech recognition, machine translation, and driverless cars.
Deep learning is an artificial intelligence technology that enables computer vision, speech recognition in mobile phones, machine translation, AI games, driverless cars, and other applications. When we use consumer products from Google, Microsoft, Facebook, Apple, or Baidu, we are often interacting with a deep learning system. In this volume in the MIT Press Essential Knowledge series, computer scientist John Kelleher offers an accessible and concise but comprehensive introduction to the fundamental technology at the heart of the artificial intelligence revolution.
Kelleher explains that deep learning enables data-driven decisions by identifying and extracting patterns from large datasets; its ability to learn from complex data makes deep learning ideally suited to take advantage of the rapid growth in big data and computational power. Kelleher also explains some of the basic concepts in deep learning, presents a history of advances in the field, and discusses the current state of the art. He describes the most important deep learning architectures, including autoencoders, recurrent neural networks, and long short-term networks, as well as such recent developments as Generative Adversarial Networks and capsule networks. He also provides a comprehensive (and comprehensible) introduction to the two fundamental algorithms in deep learning: gradient descent and backpropagation. Finally, Kelleher considers the future of deep learning—major trends, possible developments, and significant challenges.
Break On Through
Authors: Richert Lucas 
Published: November 2019

“Antipsychiatry,” Esalen, psychedelics, and DSM III: Radical challenges to psychiatry and the conventional treatment of mental health in the 1970s.
The upheavals of the 1960s gave way to a decade of disruptions in the 1970s, and among the rattled fixtures of American society was mainstream psychiatry. A “Radical Caucus” formed within the psychiatric profession and the “antipsychiatry” movement arose. Critics charged that the mental health establishment was complicit with the military-industrial complex, patients were released from mental institutions, and powerful antipsychotic drugs became available. Meanwhile, practitioners and patients experimented with new approaches to mental health, from primal screaming and the therapeutic use of psychedelics to a new reliance on quantification. In Break on Through, Lucas Richert investigates the radical challenges to psychiatry and to the conventional treatment of mental health that emerged in the 1970s and the lessons they offer for current debates.
Drawing on archives and government documents, medical journals, and interviews, and interweaving references to pop (counter)culture into his account, Richert offers fascinating stories of the decade's radical mental health practices. He discusses anti–Vietnam War activism and the new diagnosis of post–traumatic stress disorder given to some veterans; the radical psychiatrists who fought the system (and each other); the entry of New Age–style therapies, including Esalen's Human Potential Movement, into the laissez-faire therapeutic marketplace of the 1970s; the development of DSM III; and the use of LSD, cannabis, and MDMA.
Many of these issues have resonance today. Debates over medical marijuana and microdoses of psychedelics echo debates of the 1970s. With rising rates of such disorders as anxiety and depression, practitioners and patients continue to search for therapeutic breakthroughs.
The Meat Question
Authors: Berson Josh 
Published: November 2019

A provocative argument that eating meat is not what made humans human and that the future is not necessarily carnivorous.
Humans are eating more meat than ever. Despite ubiquitous Sweetgreen franchises and the example set by celebrity vegans, demand for meat is projected to grow at twice the rate of demand for plant-based foods over the next thirty years. Between 1960 and 2010, per capita meat consumption in the developing world more than doubled; in China, meat consumption grew ninefold. It has even been claimed that meat made us human—that our disproportionately large human brains evolved because our early human ancestors ate meat. In The Meat Question, Josh Berson argues that not only did meat not make us human, but the contemporary increase in demand for meat is driven as much by economic insecurity as by affluence. Considering the full sweep of meat's history, Berson concludes provocatively that the future is not necessarily carnivorous.
Berson, an anthropologist and historian, argues that we have the relationship between biology and capitalism backward. We may associate meat-eating with wealth, but in fact, meat-eating is a sign of poverty; cheap meat—hunger killing, easy to prepare, eaten on the go—enables a capitalism defined by inequality. To answer the meat question, says Berson, we need to think about meat-eating in a way that goes beyond Paleo diets and PETA protests to address the deeply entwined economic and political lives of humans and animals past, present, and future.
Molecular dynamics simulations of pentacene thin film growth: Stability of nuclei comprising standing molecules and their subsequent growth
Authors: Ikeda Susumu 
Published: November 2019

Abstract
Molecular dynamics (MD) simulations were applied to the study of nucleation and growth of pentacene thin films, and stability of clusters (nuclei) comprising standing molecules was investigated. In simulations, the clusters consisting of more than ten standing molecules could stably exist on hydrophobic surfaces, while several tens of molecules were necessary for stabilization on hydrophilic surfaces. Furthermore, the stabilized clusters could grow by incorporating additional molecules in MD simulations. These results suggest that nucleation occurs on hydrophobic surfaces easier than on hydrophilic surfaces and the critical size of the nuclei of “standing” pentacene is about ten molecules on hydrophobic surfaces.
“Resources-Demands Ratio”: Translating the JD-R-Model for company stakeholders
Authors: Jenny Gregor J , Bauer Georg F , Füllemann Désirée , Broetje Sylvia , Brauchli Rebecca 
Published: November 2019

Abstract

Objectives
Practitioners and organizational leaders are calling for practical ways to explain and monitor factors that affect workplace health and productivity. This article builds on the well-established Job Demands-Resources (JD-R) model and proposes an empirically tested ratio that aggregates indicators of job resources and demands. In this study, we calculate a ratio of generalizable job resources and demands derived from the JD-R model and then translate the ratio into the language of company stakeholders.

Methods
We calculated a ratio based on measures applied in a large stress management intervention study (n = 2983) and report the findings from cross-sectional analysis with health and productivity outcomes from same-source and separate-source data.

Results
Findings showed a strong and unambiguous increase in health and productivity measures with each step of increase in the ratio. Loss in explained variance due to aggregation of two factors into a single ratio is small for measures which are known to be predicted by both factors simultaneously.

Conclusions
A translation and visualization of the ratio that is accessible to practitioners and organizational leaders is presented and its use in companies discussed.
From Straw to Device Interface: Carboxymethyl‐Cellulose‐Based Modified Interlayer for Enhanced Power Conversion Efficiency of Organic Solar Cells
Authors: Wu Junying , Liu Yanjun , Islam Amjad , Zheng Qinghong , Li Jianguo , Ji Wei , Chen Lihui , Ouyang Xinhua 
Published: November 2019

AbstractAdvanced interface materials made from petrochemical resources have been extensively investigated for organic solar cells (OSCs) over the past decades. These interface materials have demonstrated excellent performances in OSC devices. However, the limited resources, high‐cost, and non‐ecofriendly nature of petrochemical‐based interface materials restrict their commercial applications. Here, a facile and effective approach to prepare cellulose and its derivatives as a cathode interface layer for OSCs with enhanced performance from rice straw of agroforestry residues is demonstrated. By employing this carboxymethyl cellulose sodium (CMC) into OSCs, a highly efficient inverted OSC is constructed, and a power conversion efficiency (PCE) of 12.01% is realized using poly[(2,6‐(4,8‐bis(5‐(2‐ethyl‐hexyl)‐thiophen‐2‐yl)‐benzo[1,2‐b:4,5‐b′] dithiophene))‐alt‐(5,5‐(1′,3′‐di‐2‐thienyl‐5′,7‐bis(2‐ethylhexyl)benzo[1′,2′‐c: 4′,5′‐c′]dithiophene‐4,8‐dione): 3,9‐bis(2‐methylene‐((3‐(1, 1‐dicyanomethylene)‐6/7‐methyl)‐indanone))‐5,5,11,11‐tetrakis(4‐hexylphenyl)‐dithieno[2,3‐d: 2′,3′‐d′]‐s‐indaceno[1,2‐b: 5, 6‐b′]dithiophene as the active layer, which shows over 9.4% improvement in PCE compared to that of a device without the CMC layer (PCE = 10.98%), especially the enhancement in short‐circuit current. The improved current densities and PCEs are attributed to the reduced work function, enhanced absorption, and improved interfacial contact by using CMC and ZnO as co‐interface. This approach of fabricating interface materials from biorenewable sources for OSCs is simple, scalable, and cost‐effective, representing a promising direction for the development of smart interface and green electronics.
Effect of Chemical Structure of Solid Lipid Matrix on Its Melting Behavior and Volumetric Expansion in Pressurized Carbon Dioxide
Authors: Yang Junsi , Ciftci Ozan N. 
Published: November 2019

AbstractSupercritical carbon dioxide (SC‐CO2) technology offers new opportunities for green processing of lipids; however, there is little information of the melting behavior and volumetric expansion of solid lipids in pressurized CO2. In this study, melting behavior and volumetric expansion of two different solid lipid classes and the effect of the structural differences within the same lipid class on the melting behavior in pressurized CO2 were investigated. The melting point of the solid lipids decreased linearly with increasing pressures up to a certain level; then, it stayed constant. The highest melting point depression was observed for soybean oil monoacylglycerol (SO‐MAG) at 51.5 °C/110 bar, whereas the lowest was for fully hydrogenated soybean oil (FHSO) containing 30% SO‐MAG at 55.0 °C/79 bar. Melting point depression depended on lipid class. SO‐MAG exhibited a higher melting point depression than FHSO (triacylglycerol form), and its blends with SO‐MAG. There was no difference in melting point depression between glyceryl 1,2‐distearate and glyceryl 1,3‐distearate up to 200 bar (P > 0.05). A positive correlation between the melting point depression and volumetric expansion of solid lipids was observed. The highest volumetric expansion was for SO‐MAG in the linear region of the melting point depression curve, achieving 14.4% expansion compared to 9.3% for FHSO (P < 0.05). The highest dT/dP value (0.17 °C bar−1) was obtained for SO‐MAG, whereas the FHSO (0.09 °C bar−1) had the lowest one. Findings of this study will help optimize solid lipid‐involving SC‐CO2 processes for better protection of heat‐sensitive compounds while improving energy efficiency.
Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy, Part II: Implementation
Authors: Dunn Debra , Ciccarelli Eileen , Moltzen Nina 
Published: November 2019

ABSTRACTCytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is an extensive procedure used to treat peritoneal carcinomatosis, which is either primary or secondary to other cancers (eg, ovarian, colorectal, appendiceal) that have metastasized to the peritoneum. Morbidity, mortality, and quality of life have improved for patients selecting CRS with HIPEC as a cancer treatment. At Holy Name Medical Center in Teaneck, New Jersey, an interdisciplinary team was established to plan and coordinate performing this new procedure in the OR. The team created a written protocol for implementing CRS with HIPEC before patients were scheduled for surgery. This article explores the perioperative facets of implementing CRS with HIPEC and discusses care of the patient undergoing CRS with HIPEC, with a focus on perioperative nursing considerations.
Guideline Implementation: Transmission‐Based Precautions
Authors: Link Terri 
Published: November 2019

ABSTRACTTransmission of an infectious agent requires a source of infection, a mode of transmission, and a vulnerable host. The most important interventions for preventing infection transmission are hand hygiene and use of standard precautions for all patients. Other precautions are based on how an organism is transmitted; these include contact, airborne, and droplet precautions. The cornerstone of transmission‐based precautions is appropriate use of personal protective equipment to protect personnel and patients from infection. This article discusses key takeaways from the “AORN guideline for transmission‐based precautions,” including using standard precautions; wearing personal protective equipment when exposure to blood, body fluids, or other potentially infectious materials is anticipated; and using contact precautions during care of patients known or suspected to be infected or colonized with pathogens transmitted by direct or indirect contact. Perioperative RNs should review the complete guideline for additional information and for guidance when writing and updating policies and procedures.
Low‐cost and biodegradable cellulose/PVP/activated carbon composite membrane for brackish water treatment
Authors: Ramadoss Preethi , Regi Thankam , Rahman Mohammed Isfahur , Arivuoli D. 
Published: November 2019

ABSTRACTA simple fabrication of a biodegradable membrane for use in water purification systems is presented in this work. Sodium carboxymethyl cellulose and PVP are dissolved in water and crosslinked with citric acid. The presence of glycerol has given immense flexibility and mechanical strength to the membrane. The addition of activated charcoal has enhanced its purification and dye adsorption capabilities at room temperature in dark and light conditions. The polymer semiconductor composites are completely soil degradable within a week and the membrane also exhibits good electrical conductivity when compared to the membrane without charcoal. The addition of glycerol has acted as molecular spacer between polymers composite's monomer backbone that allows good electron mobility of 9.9 cm2 V−1 s−1. The dye adsorption efficiency of the material with two commonly used toxic textile dyes is found to be 100% for methyl orange and up to 57% for Rhodamine B within 3 h. The material shows good dye adsorption efficiency under dark and light conditions with acidic, neutral, and alkaline pH. Salt rejection was also found to increase from 25.3 to 64.4% with applied voltage. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48746.
Synthesis of multifunctional core–shell toughening agent with light stability and its application in polycarbonate
Authors: Wang Lin , He Hui , Li Kunquan , Chen Rui , Chen Pingxu , Cen Yin 
Published: November 2019

ABSTRACTA light stabilizer compound of 2‐(2′‐propionyloxy‐5′‐methylphenyl) benzotriazole (AMB) was synthesized by the esterification of the 2‐(2′‐hydroxy‐5′‐methylphenyl) benzotriazole with acryloyl chloride (AC), and the AMB was then copolymerized with the methyl methacrylate (MMA), butyl acrylate (BA), and silicone monomers (D4) to prepare the silicone light toughener of poly(D4‐MMA‐BA‐AMB). Effects of the AMB monomer on the conversion and polymerization stability and the toughening and photostabilizing effects of the poly(D4‐MMA‐BA‐AMB) on the polycarbonate (PC) were studied. The prepared multifunctional toughening agent was characterized by Fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, thermogravimetric analyzer, transmission electron microscopy, dynamic light scattering analyzer, and ultraviolet absorption spectroscopy. Results show that the prepared poly(D4‐MMA‐BA‐AMB) toughening agent possessed core–shell structure and could effectively absorb the ultraviolet rays. Although the addition of the poly(D4‐MMA‐BA‐AMB) toughening agent had a negative effect on the tensile strength of the PC, it could greatly improve the low‐temperature notched impact strength, toughness performance, and yellowness performance of PC products after UV irradiation. Compared with the silicone toughening agent, the toughening agent of the poly(D4‐MMA‐BA‐AMB) had better anti‐ultraviolet property for the PC/poly(D4‐MMA‐BA‐AMB) composite. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2020,137, 48747.
Comprehensive Basicity Scales for N‐Heterocyclic Carbenes in DMSO: Implications on the Stabilities of N‐Heterocyclic Carbene and CO2 Adducts
Authors: Wang Zhen , Xue Xiao‐Song , Fu Yanhua , Ji Pengju 
Published: November 2019

AbstractA very broad acidity scale (≈40 pK units) for about 400 N‐heterocyclic carbene precursors (NHCPs) with various backbones and electronic features, including imidazolylidenes, 1,2,4‐triazolylidenes, cyclic diaminocarbenes (CDACs), diamidocarbenes (DACs), thiazolylidenes, cyclic (alkyl)(amino)carbenes (CAACs) and mesoionic carbenes (MICs), was established in DMSO by a well examined computational method. Varying the backbone structure or flanking N‐substituents can have different extent of acidifying effects, depending on both the nature and number of substituent(s). The Gibbs energies (ΔGrs) for the reactions between the corresponding NHCs and CO2 were also calculated. There is a good linear correlation between the pKas of most NHCPs and ΔGrs, suggesting that a greater basicity of NHC leads to a more stable NHC‐CO2 adduct. Interestingly, the nearby asymmetric environment has virtually no differential effect on the acidities of the chiral NHCP enantiomers, but has a pronounced effect on the ΔGr values.