bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors associated with MRI detection of occult lesions in newly diagnosed breast cancers
Authors: Wecsler Julie , Jeong Young Ju , Raghavendra Akshara S. , Mack Wendy J. , Tripathy Debasish , Yamashita Mary W. , Sheth Pulin A. , Hovanessian Larsen Linda , Russell Christy A. , MacDonald Heather , Sener Stephen F. , Lang Julie E. 
Published: January 2020

AbstractBackgroundThe use of preoperative magnetic resonance imaging (MRI) for newly diagnosed breast cancer remains controversial. We examined factors associated with detection of occult multicentric, multifocal, and contralateral malignant lesions only seen by MRI.MethodsWe performed a retrospective analysis of consecutive patients undergoing preoperative MRI for breast cancer. Clinicopathologic data were assessed regarding the findings of multifocality, multicentricity, and the presence of contralateral lesions. We analyzed the association of factors with these findings on MRI.ResultsOf 857 patients undergoing MRI, 770 patients met inclusion criteria. Mean age was 54.7 years. Biopsy‐proven detection rates by MRI for multifocal, multicentric, and contralateral cancers were 6.2% (48 of 770), 1.9% (15 of 770) and 3.1% (24 of 770), respectively. African American race and heterogeneously or extremely dense mammographic density were associated with multifocal cancers on MRI. Larger lesion size and mammographic density were associated with multicentric cancers. Invasive lobular carcinoma (ILC) and progesterone receptor (PR)‐positivity were associated with contralateral cancers.ConclusionsAfrican American race, heterogeneously or extremely dense mammographic density, ILC, and PR‐positivity were associated with additional biopsy‐proven cancers based on MRI. These factors should be considered when assessing the clinical utility of preoperative breast MRI.
Diagnosis of Acute Heart Failure Using Inferior Vena Cava Ultrasound
Authors: Darwish Omar S. , Mahayni Abdullah , Kataria Saisha , Zuniga Eric , Zhang Lishi , Amin Alpesh 
Published: January 2020

ObjectivesThe utility of bedside inferior vena cava (IVC) ultrasound (US) in the diagnosis of heart failure (HF) is unclear. The aim of this study was to determine whether IVC parameters in patients with acute heart failure (AHF) are statistically different from those without HF.MethodsThe MEDLINE database of English‐language publications from 1966 to August 2018 was searched. Retrospective and prospective studies that included either IVC expiratory diameter (IVCexp) or IVC collapsibility index (IVC‐CI) values were collected in patients with and without HF. to determine whether there was a statistical difference in the IVC parameters between these groups.ResultsA total of 27 articles with a total of 1472 patients with AHF were included. The standard mean differences for the IVCexp and IVC‐CI for the control group versus the AHF group were found to be statistically significant (P < .0001). The combined mean IVCexp values were 15.11 mm (95% confidence interval [CI], 14.19–16.02 mm) for the control group and 20.26 mm (95% CI, 14.82–25.71 mm) for the AHF group. The combined mean IVC‐CI values were 61.6% (95% CI, 48.4%–74.7%) for the control group and 30.5% (95% CI, 26.4%–34.6%) for the AHF group.ConclusionsBedside IVC US showed that a statistically significant difference existed in the IVC parameters between patients with and without AHF. Based on mean calculations, an IVCexp of greater than 2.0 cm and an IVC‐CI of less than 30% are reasonable cutoffs to suggest that a patient with acute dyspnea is more likely to have AHF than a non‐AHF condition. Given the high degree of heterogeneity across the studies and the high risk of bias, larger randomized studies are warranted to explore the use of IVC US in patients with HF.
Experimental measurement of rolling bearing torque loss in a modified Four‐Ball machine: An improved setup
Authors: Marques Pedro M. T. , Martins Ramiro C. , Seabra Jorge H. O. 
Published: January 2020

AbstractThis work presents an improved method for the measurement of the rolling bearing torque loss using a modified Four‐Ball machine. The new assembly allowed precise and accurate rolling bearing torque loss, while operating at constant temperature, controlled by means of liquid cooling‐heating system in which a thermal fluid is carried through the centre of the driving shaft. Several rolling bearing test campaigns are performed, using a fully formulated ISO VG 150 poly‐α‐olefin gear oil. The frictional torque loss is measured and compared with models available and the surface roughness of the rolling bearing races is observed using an optical profilometer.
Probing the nonuniform corrosion of pipeline weldments under stepwise increasing solution temperature using a coupled multielement electrical resistance sensor
Authors: Zhu Yesen , Xu Yunze , Song Shide , Wang Xiaona , Liu Gang , Huang Yi 
Published: January 2020

AbstractA coupled multielement electrical resistance sensor (MERS) was designed to probe the nonuniform corrosion of an X65 pipeline weldment under a stepwise increasing solution temperature. In conjunction with electrochemical impedance spectroscopy (EIS) measurements, the initiation and propagation of the nonuniform corrosion on different welding areas, that is, base metal (BM), heat‐affected zone (HAZ), and welding metal (WM) were well understood. The results show that the contributions of galvanic current (current flowing across the three different welding areas) and internal current (current flowing in a certain welding area) for the steel loss of BM, HAZ, and WM were significantly different under each solution temperature. The main contributor to the steel loss of HAZ gradually transformed from internal current to galvanic current with the solution temperature increasing. The WM would change from anodes to cathodes due to the preprecipitation of the FeCO3 crystals on WM when the solution temperature increased over 40°C. The BM would transform from cathodes to anodes at 40°C and the steel loss of BM was mainly induced by the internal current in BM over the whole test duration.
Changes in mechanical properties of dental alloys induced by saliva and oral probiotic supplements
Authors: Musa Trolic I. , Turco G. , Contardo L. , Perissinotto F. , Katic V. , Spalj S. 
Published: January 2020

AbstractThe effects of the saliva and oral probiotic supplements on roughness, friction and microhardness of the stainless steel (SS) and nickel‐titanium (NiTi) alloys used in dentistry was studied. The specimens of stainless steel, uncoated, rhodium‐coated and nitrided NiTi were exposed to artificial saliva with pH 4.8 and artificial saliva with addition of probiotic supplements containing bacteria Lactobacillus reuteri Prodentis through 28 days. First 5 days specimens were subjected to thermocycling to simulate intraoral conditions, 2500 cycles from 5 °C to 50 °C and the following days to the temperature of the 37±2 °C. Analyses demonstrated that oral probiotic supplements do not influence microhardness, roughness or friction of stainless steel above the influence of saliva. Probiotics increase roughness in NiTi, but without significant influence on friction, while microhardness in NiTi is not influenced. Surface nitriding reduces the influence of probiotics on roughness while rhodium coating increases it.
Effect of friction stir welding process parameters on the tensile strength of dissimilar aluminum alloy AA2024‐T3 and AA7075‐T6 joints
Authors: Padmanaban R. , Balusamy V. , Vaira Vignesh R. 
Published: January 2020

AbstractThis work investigates the influence of friction stir welding parameters on the mechanical properties of the dissimilar joint between AA2024‐T3 and AA7075‐T6. Experiments are conducted consistent with the three‐level face‐centered composite design. Response surface methodology is used to develop the regression model for predicting the tensile strength of the joints. The analysis of variance technique is used to access the adequacy of the developed model. The model is used to study the effect of key operating process parameters namely, tool rotation speed, welding speed and shoulder diameter on the tensile strength of the joints. The results indicate that friction stir welding of aluminum alloys at a tool rotation speed of 1050 min−1, welding speed of 40 mm/min and a shoulder diameter of 17.5 mm would produce defect less joint with high tensile strength.
Benthic Habitats, as Derived from Classification of Side-Scan-Sonar Mapping Data, Are Important Determinants of Reef-Fish Assemblage Structure in the Eastern Gulf of Mexico
Authors: Switzer Theodore S. , Tyler-Jedlund Amanda J. , Keenan Sean F. , Weather Eric J. 
Published: January 2020

Abstract
Increasingly restrictive management regulations have greatly reduced the utility of fishery-dependent data for characterizing temporal changes in the abundance of managed fish populations, so fishery-independent data are becoming more important for the accurate assessment of stock status. A notable downside to fishery-independent data is the high cost of conducting surveys, and efforts to maximize survey efficiency are critical given ongoing reductions in agency funding. We conducted a pilot study to explore the utility of classifying side-scan-sonar mapping data to provide a practical a priori characterization of reef habitat in the eastern Gulf of Mexico. An analysis of side-scan-sonar mapping data identified five distinct reef habitat types (low-relief hard bottom, mixed hard bottom, fragmented hard bottom, ledges, and potholes) that were subsequently sampled with stereo baited remote underwater video (S-BRUV) arrays and trap-mounted GoPro cameras. The permutational analysis of variance indicated that the assemblage structure of reef fish differed significantly (P &lt;0.01) among all of the pairs of habitats except ledges and fragmented hard bottom; assemblage structure did not differ among cameras (P =0.45). Overall species richness and diversity were significantly higher in the habitats with greater vertical relief, as were the abundances of several economically and ecologically important reef fishes, although many taxa were observed across all of the habitat types. Benthic habitats that are identified from side-scan-sonar mapping data are important determinants of reef-fish assemblage structure and may prove to be useful as a stratification scheme for reef-fish surveys, although additional research is necessary to explore the transferability of these results to the rest of the eastern Gulf of Mexico.
Pelvic floor and abdominal muscle responses during hypopressive exercises in women with pelvic floor dysfunction
Authors: Navarro Brazález Beatriz , Sánchez Sánchez Beatriz , Prieto Gómez Virginia , De La Villa Polo Pedro , McLean Linda , Torres Lacomba María 
Published: January 2020

AbstractAimTo measure the neuromuscular activation of the pelvic floor and abdominal muscles concurrently with vaginal closure forces induced during a hypopressive exercise (HE) and to identify the contribution of the HEs sequences (posture and maneuver) in the muscle's activation.MethodsA cross‐sectional study design was employed. Sixty‐six women who had participated in a physical therapy program focused on HEs were recruited. Pelvic floor muscle (PFM) activation was measured using surface electromyography (sEMG) in supine and in the orthostatic position, and vaginal closure force was measured through vaginal dynamometry in supine. Activation of the abdominal, gluteal, and hip adductor muscles was measured using sEMG. Maximum effort voluntary contractions (MVCs) of the PFMs and reference contractions of the abdominal and hip muscles were acquired for normalization purposes. A HE was then performed in a supine position with one leg raised, then in an orthostatic position.ResultsDuring the supine HE, the peak PFM sEMG amplitude was 74.4% to 86.5% (49.6%‐109.6%) of MVC, the peak vaginal closure force was between 51.2% and 55.7% (95.5%‐382.9%) of MVC, and the muscles of the lateral abdominal wall were activated between 25.4% and 35.3% of the reference contraction. During the orthostatic HE, PFM activation was 61.4% (40.1%‐105.6%) of MVC, and the lateral abdominal wall muscles contracted at 22.8% of the reference activation level.ConclusionsThe PFMs, abdominal, gluteal, and adductor muscles are activated during the performance of a HE. The activation level of the PFMs and abdominal muscles is likely insufficient to result in strength gains; however, they could have an endurance effect.
Interpretation of uroflow curves: A global survey measuring inter and intra rater reliability
Authors: Netto Jose M. B. , Hittelman Adam , Lambert Sarah , Murphy Kaitlyn , Collette‐Gardere Therese , Franco Israel 
Published: January 2020

AbstractIntroductionThere is a large amount of intra and inter observer variability in defining curve shapes. This study aims to evaluate inter and intra rater reliability (RR) on evaluating uroflow curves in a broad spectrum of international practitioners.MethodsEight hundred sixty‐four questionnaires were sent by email to health professionals that care for children with voiding dysfunction. It included demographic questions and 11 different uroflow curves and two duplicates.ResultsFour hundred forty‐one emails were opened and 29.5% of those responded. Seventy percent of responders were physicians, including 46% pediatric urologists. Europe, South America, North America, Oceania, and Asia represented respondents. For the repeated bell smooth curve the intra rater agreement was 82.1% utilizing the International Children's Continence Society (ICCS) classification and 92.3% for the shape of the curve (bell, plateau, and tower [BPT]) (P = .04). For the repeated interrupted plateau curve it was 69.5% and 97.5% for ICCS and for the continuity of the curve (smooth or fractionated [SF]) classifications, respectively (P < .001). The curves were then divided into two groups for evaluation of inter RR. For the set of seven smooth curves, the inter RR was low in all classifications with α = .282, .497, and .242 for ICCS, SF, and BPT, respectively. The group of six fractionated curves showed a slightly better agreement with α = .533, .404, and .662 for ICCS, SF, and BPT, respectively.ConclusionsThis is the largest study looking at inter and intra RR of uroflows in a disparate population of readers. It was evident from our findings that inter RR was poor and additionally intra RR was equally poor, indicating the unreliability of uroflow shapes to be used for research purposes.
Factorized sensitivity estimation for artifact suppression in phase‐cycled bSSFP MRI
Authors: Bıyık Erdem , Keskin Kübra , UH Dar Salman , Koç Aykut , Çukur Tolga 
Published: January 2020

Objective: Balanced steady‐state free precession (bSSFP) imaging suffers from banding artifacts in the presence of magnetic field inhomogeneity. The purpose of this study is to identify an efficient strategy to reconstruct banding‐free bSSFP images from multi‐coil multi‐acquisition datasets.Method: Previous techniques either assume that a naïve coil‐combination is performed a priori resulting in suboptimal artifact suppression, or that artifact suppression is performed for each coil separately at the expense of significant computational burden. Here we propose a tailored method that factorizes the estimation of coil and bSSFP sensitivity profiles for improved accuracy and/or speed.Results: In vivo experiments show that the proposed method outperforms naïve coil‐combination and coil‐by‐coil processing in terms of both reconstruction quality and time.Conclusion: The proposed method enables computationally efficient artifact suppression for phase‐cycled bSSFP imaging with modern coil arrays. Rapid imaging applications can efficiently benefit from the improved robustness of bSSFP imaging against field inhomogeneity.
A case of probable interpersonal violence from the Early Neolithic site at Smilčić, Croatia
Authors: Janković Ivor , Marijanović Brunislav , Čavka Mislav , Carić Mario , Novak Mario 
Published: January 2020

AbstractArchaeological excavations at the Early/Middle Neolithic site at Smilčić‐Barica in 2016/2017 revealed skeletal remains of three people. Of particular interest is the skeleton from Grave 2, directly dated to 5616 and 5485 cal BCE, that is, to the Early Neolithic Impresso Pottery Culture. The skeleton was positioned on its left side, in a crouched position with bended knees and its right arm flexed at the elbow. Based on metric and morphological observations, the skeleton belongs to a young male, aged between 25 and 35 years. The most interesting feature is a penetrating trauma, probably caused by a projectile, located at intertrochanteric crest on the posterior proximal side on the left femur. A 15 × 4 × 3 mm lithic fragment is still embedded in the bone. Due to post‐mortem damage around the injury, it was not possible to establish possible signs of healing and/or inflammation. However, osteogenic reaction around the fragment is noted on computer tomography, indicating survival for a longer period. This is the earliest example of interpersonal violence recorded on the eastern Adriatic coast.
The WORD: Outcomes of a Behavioral Weight Loss Maintenance Effectiveness Trial in Rural Black Adults of Faith
Authors: Yeary Karen H. Kim , Cornell Carol E. , Moore Page C. , Gauss C. Heath , Prewitt T. Elaine , Turner Jerome 
Published: January 2020

ObjectiveRural black communities bear a disproportionate burden of obesity. To increase reach among underserved groups, community‐based weight loss and maintenance interventions are crucial.MethodsThe Diabetes Prevention Program (DPP) was adapted for rural black adults of faith to create The Wholeness, Oneness, Righteousness, Deliverance (WORD) trial, a group‐based, community health worker–delivered weight loss intervention. A Weight Loss Only arm (16 sessions) was compared with a Weight Loss + Maintenance arm (16 + 12 sessions) in a cluster randomized controlled trial of 31 churches (n = 440). Weight and related behaviors were assessed at 0, 6, 12, and 18 months.ResultsThe WORD produced weight loss from baseline to 6 months (percentage body weight change −2.47 [−3.13 to −1.80]). Among those who lost 5% of their baseline weight, there was a statistical trend of lower weight regain in the Weight Loss + Maintenance arm compared with control. Maintenance arm participants reported higher activity at 12 months. There were no between‐arm differences at 18 months.ConclusionsThe WORD produced weight loss from baseline to 6 months on par with that produced by other DPP adaptations for black communities, including adaptations using health professionals. Weight regain was also consistent with that reported in prior literature. Continuing sessions as part of the church’s mission may foster adoption of DPP‐based weight loss programs.
Implantation‐based passivating contacts for crystalline silicon front/rear contacted solar cells
Authors: Limodio Gianluca , Yang Guangtao , De Groot Yvar , Procel Paul , Mazzarella Luana , Weber Arthur W. , Isabella Olindo , Zeman Miro 
Published: January 2020

AbstractIn this work, we develop SiOx/poly‐Si carrier‐selective contacts grown by low‐pressure chemical vapor deposition and boron or phosphorus doped by ion implantation. We investigate their passivation properties on symmetric structures while varying the thickness of poly‐Si in a wide range (20‐250 nm). Dose and energy of implantation as well as temperature and time of annealing were optimized, achieving implied open‐circuit voltage well above 700 mV for electron‐selective contacts regardless the poly‐Si layer thickness. In case of hole‐selective contacts, the passivation quality decreases by thinning the poly‐Si layer. For both poly‐Si doping types, forming gas annealing helps to augment the passivation quality. The optimized doped poly‐Si layers are then implemented in c‐Si solar cells featuring SiO2/poly‐Si contacts with different polarities on both front and rear sides in a lean manufacturing process free from transparent conductive oxide (TCO). At cell level, open‐circuit voltage degrades when thinner p‐type poly‐Si layer is employed, while a consistent gain in short circuit current is measured when front poly‐Si thickness is thinned down from 250 to 35 nm (up to +4 mA/cm2). We circumvent this limitation by decoupling front and rear layer thickness obtaining, on one hand, reasonably high current (JSC‐EQE = 38.2 mA/cm2) and, on the other hand, relatively high VOC of approximately 690 mV. The best TCO‐free device using Ti‐seeded Cu‐plated front contact exhibits a fill factor of 75.2% and conversion efficiency of 19.6%.
Glycine Receptor Complex Analysis Using Immunoprecipitation‐Blue Native Gel Electrophoresis‐Mass Spectrometry
Authors: van der Spek Sophie J. F. , Koopmans Frank , Paliukhovich Iryna , Ramsden Sarah L. , Harvey Kirsten , Harvey Robert J. , Smit August B. , Li Ka Wan 
Published: January 2020

AbstractThe pentameric glycine receptor (GlyR), comprising the α1 and β subunits, is a major inhibitory ionotropic receptor in brainstem and spinal cord. GlyRs interact with gephyrin (GPHN), a scaffold protein that anchors the GlyR in the plasma membrane and enables it to form clusters in glycinergic postsynapses. Using an interaction proteomics approach, evidence of the ArfGEFs IQ motif and Sec7 domain 3 (IQSEC3) and IQ motif and Sec7 domain 2 (IQSEC2) as two novel synaptic proteins interacting with GlyR complexes is provided. When the affinity‐isolated GlyR complexes are fractionated by blue native gel electrophoresis and characterized by mass spectrometry, GlyR α1β‐GPHN appears as the most abundant complex with a molecular weight of ≈1 MDa, and GlyR α1β‐GPHN‐IQSEC3 as a minor protein complex of ≈1.2 MDa. A third GlyR α1β‐GPHN‐IQSEC2 complex exists at the lowest amount with a mass similar to the IQSEC3 containing complex. Using yeast two‐hybrid it is demonstrated that IQSEC3 interacts with the GlyR complex by binding to the GPHN G domain at the N‐terminal of the IQSEC3 IQ‐like domain. The data provide direct evidence of the interaction of IQSEC3 with GlyR‐GPHN complexes, underscoring a potential role of these ArfGEFs in the function of glycinergic synapses.
The mediating effect of activity restriction on the relationship between perceived physical symptoms and depression in cancer survivors
Authors: Hata Kotone , Ono Haruka , Ogawa Yuko , Suzuki Shin‐ichi 
Published: January 2020

AbstractPurposeSeveral studies have explored factors causing depression in cancer survivors, including perceived physical symptoms. Another critical factor in the depression symptomatology of cancer survivors is activity restriction (AR). We investigated how AR mediate the effects of perceived pain and fatigue on depression in cancer survivors.MethodsCancer survivors (n = 61; mean age 56.16 years) that were recruited through cancer support groups in Japan participated in this study. Participants completed a battery of questionnaires comprising demographic and clinical information, the Pain Catastrophizing Scale, the Cancer Fatigue Scale, the Activity Restriction Scale for Cancer Patients, and the Hospital Anxiety and Depression Scale.ResultsMediation analysis indicated that AR partially mediates the effect of pain on depression. Direct paths from pain to AR, AR to depression, and pain to depression were significant (P < .005). Moreover, indirect paths from pain to AR, AR to depression, and pain to depression were also significant at the 95% level [0.04‐0.13]. However, AR did not mediate the effect of fatigue on depression, and fatigue had a significant direct path to both AR and depression (P < .005).ConclusionThis study aimed to explore the mediating effect of AR in the relationships of perceived pain and fatigue and depression in cancer survivors. We found that AR mediates perceived pain to depression, however not for perceived fatigue. In addition, because AR was experienced in the face of any survivorship period, AR may need to be treated as a long‐term effect of the cancer diagnosis