bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH SUBSTITUSI TEPUNG DAUN SINGKONG (Manihot Utilisima) YANG DIFERMENTASI MENGGUNAKAN Rhizopus sp. PADA PAKAN TERHADAP PERTUMBUHAN DAN KELANGSUNGAN HIDUP BENIH IKAN MAS (Cyprinus carpio)
Authors: Rahmadani Sri , Setyowati Dewi Nur’aeni , Lestari Dewi Putri 
Published: May 2020

Penelitian ini bertujuan untuk untuk mengetahui pertumbuhan dan kelangsungan hidup benih ikan mas (Cyprinus carpio) yang diberi pakan tepung daun singkong fermentasi menggunakan Rhizopus sp. Metode yang digunakan dalam penelitian ini adalah metode eksperimental menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 5 perlakuan an 3 kali ulangan sehingga diperoleh 15 unit percobaan, yakni P0 (tanpa penambahan tepung daun singkong fermentasi), P1 (penambahan tepung daun singkong fermentasi 10%), P2 (penambahan tepung daun singkong fermentasi 15%), P3 (penambahan tepung daun singkong fermentasi 20%), P4 (penambahan tepung daun singkong fermentasi 25%). Hasil penelitian menunjukkan bahwa tidak adanya pengaruh yang nyata terhadap pertumbuhan mutlak, laju pertumbuhan harian, Rasio Konversi Pakan (FCR), dan Kelangsungan Hidup ikan mas. Diketahui bahwa P1 (penambahan tepung daun singkong fermentasi 10%) merupakan perlakuan terbaik pada semua parameter uji. Sedangkan untuk kelangsungan hidup P3 (penambahan tepung daun singkong fermentasi 20%) dan P4 (penambahan tepung daun singkong fermentasi 25%) merupakan perlakuan terbaik untuk kelangsungan hidup yaitu 100%.
PENINGKATAN NISBAH IKAN NILA JANTAN MENGGUNAKAN 17α-METILTESTOSTERON MELALUI PAKAN
Authors: Barades Epro , Hartono Dwi Puji , Witoko Pindo , Aziz Rahmadi 
Published: May 2020

Keberhasilan maskulinisasi pada ikan nila menunjukkan bahwa penggunaan hormon 17α-metiltestosteron (MT) lebih efektif dibandingkan suhu. Akan tetapi penggunaan hormon dengan cara pemberian melalui pakan belum menunjukkan hasil yang lebih baik dibandingkan dengan perendaman larva. Padahal secara aplikasi melalui pemberian pakan lebih mudah dilakukan. Oleh karena itu, pada penelitian kali ini akan dilakukan pemberian hormon melalui pakan dengan waktu percobaan pemberian pakan melebihi waktu kritis tertinggi, yaitu selama 30 dan 50 hari. D'Cotta et al. (2007) dan Ijiri et al. (2008) menyatakan bahwa waktu kritis untuk dilakukannya perubahan jenis kelamin pada ikan tilapia adalah 9-15 hari setelah pembuahan / day post fertilization / dpf. Tujuan yang ingin dicapai dalam penelitian ini adalah untuk mendapatkan periode waktu pemberian hormon 17α Metiltestosteron yang optimal melalui pakan untuk menghasilkan ikan nila monosex jantan.Perlakuan menggunakan hormon 17α-metiltestoteron dengan dosis 60 mg /kg dengan perlakuan lama pemberian pakan 0, 30 dan 50 hari. Pengaruh lama waktu pemberian pakan mengandung hormon di uji menggunakan uji anova pada selang kepercayaan 95%. Hasil yang diperoleh menunjukkan bahwa penggunaan 17α-metiltestoteron dalam sex reversal dengan dosis 60 mg/kg pakan dengan lamawaktu pemberian 0, 30 dan 50 hari menunjukkan adanya perbedaan jumlah kelamin ikan nila jantan yang dihasilkan. Akan tetapi tidak terlihat adanya perbedaan nyata pada nisbah kelamin jantan pada perlakukan 30 dan 50 hari pemebrian pakan. Sehingga dapat disimpulkan bahwa pemberian pakan hormon 17α-metiltestoteron melalui pakan selama 30- 50 hari setelah penetasan dapat meningkatkan nisbah kelamin jantan pada ikan nila lebih dari 80%.
RETRACTED NOTICE: Upacara Adat Kelahiran Sebagai Nilai Sosial Budaya Pada Masyarakat Suku Sasak Desa Pengadangan
Authors: Suhupawati Suhupawati 
Published: May 2020

Artikel yang ditulis oleh saudara Suhupawati dengan judul "Upacara Adat Kelahiran Sebagai Nilai Sosial Budaya Pada Masyarakat Suku Sasak Desa Pengadangan" dihapus dari Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan pada Volume 1 Nomor 1 2017 dengan alamat https://e-journal.hamzanwadi.ac.id/index.php/fhs/article/view/581 karena Editor menemukan artikel dengan judul yang sama telah terbit di Historis: Jurnal Kajian, Penelitian dan Pengembangan Pendidikan Sejarah pada Volume 2 Nomor 2 2017 dengan tautan url https://journal.ummat.ac.id/index.php/historis/article/view/188. Artikel dipublish dalam rentang waktu berbeda dengan isi artikel yang sama, walaupun dengan tambahan penulis berbeda. Oleh karena itu, setelah melewati pertimbangan Tim Editor demi menjaga kualitas dan integritas akademik artikel dimaksud kami cabut. Demikian untuk diketahui dan dimaklumi. Terima kasih
Eksistensi Tradisi Jati Suara dalam Acara Khitanan di Desa Darmasari Lombok Timur (Suatu Tinjauan Sejarah Budaya)
Authors: Rasyad Abdul , Hanapi Hanapi 
Published: May 2020

Tujuan penelitian ini adalah; (1) Untuk mengetahui sejarah Tradisi Jati Suara dalam acara khitanan di Desa Darmasari Kecamatan Sikur Kabupaten Lombok Timur; (2) Untuk mengetahui proses pelaksanaan Tradisi Jati Suara dalam acara khitanan di Desa Darmasari Kecamatan Sikur Kabupaten Lombok Timur; dan (3) Untuk mengetahui dampak tradisi Jati Suara terhadap kehidupan sosial dan ekonomi masyarakat di Desa Darmasari Kecamatan Sikur Kabupaten Lombok Timur. Adapun metode penelitian yang digunakan dalam penelitian ini adalah metode sejarah. Metode sejarah dalam pengertian yang lebih umum adalah penelitian suatu atas masalah dengan mengaplikasikan jalan pemecahannya dari perspektif historis. Peneliti menggunakan metode sejarah, karena dalam penelitian ini mengkaji eksistensi tradisi Jati Suara dalam Acara Khitanan di Desa Darmasari Kecamatan Sikur Kabupaten Lombok Timur. Metode sejarah merupakan cara atau teknik dalam merekonstruksi peristiwa masa lampau melalui empat tahapan kerja, yaitu heuristik, kritik sumber, interpretasi, dan historiografi.
Sintesis Tetrapeptida Linear (DPAP) Menggunakan Metode Sintesis Peptida Fasa Padat (SPPS) Dan Aktivitas Insektisidanya Terhadap Ulat Krop Kubis
Authors: Yanti Eka Fitri , Maharani Rani 
Published: May 2020

Crop cabbage worm (Crocidolomia pavonana) is one of the pests that has a bad effect on the cabbage production in Indonesia. One of the efforts that has been applied to control this pest is by using bayrusil. However, the bayrusil can cause negative effects such as poisoning and environmentally polluting effects. To prevent the undesired effects, it has been developed the use of environmentally friendly insecticide and one of them is the use of insecticidal peptide. Tripsin-modulating oostatic factor (TMOF) and ist analogues is one of the peptides that has an insecticidal activity. The aim of this research is to synthesise a linear tetrapeptide (DPAP) an analogues of TMOF and to test insecticidal activities against crop cabbage worm. A DPAP has been synthesised by Solid Phase Peptide Synthesis on 2-chlorotrytil chloride resin. Fmoc strategy was applied on the synthesis and a combination DIC/Oxime was employed in the coupling reaction.The tetrapeptidyl resin was cleaved by TFA:water:EDT (90:5:5). The peptide was purified by reverse-phase column chromatography and characterized by TOF ES-MS spectroscopy. A linear peptide was biologically tested towards the C. pavonana, showing percentage of mortality values at 1000 ppm.
Kinetika Reaksi Hidrogenasi Ester Lemak Menjadi Alkohol Lemak Dengan Katalis Tembaga- Mangan
Authors: Gunawan Melia Laniwati , Makertihartha IGBN , Subagjo Subagjo 
Published: May 2020

Fatty alcohol (FAOH) can be produced by hydrogenating of fatty acid methyl ester (FAME) using the copper-based catalyst. Copper-Chrom (Cu-Cr) is the best catalyst for high-pressure reaction condition, which is copper (Cu) as the main active component and chrom (Cr) as a promoter. Since Cr is feared to be toxic, one of the best replacement candidates is manganese (Mn). The research aims is to find the kinetic equation of hydrogenation FAME to FAOH using a Cu-Mn commercial catalyst. FAME with methyl laurate and methyl myristate as the main compounds is used as feedstock. The main products are lauryl alcohol and myristyl alcohol. The reaction was carried out in an isothermal continuous fixed bed reactor under conditions of temperature 220 – 240 oC, pressure 50 bar, and liquid hourly space velocity (LHSV) 5-12.5 hr-1. The kinetic equation is determined using the power law model. The FAME hydrogenation on copper - manganese catalyst is the half order reaction. The activation energy value is 86.32 kJ/mol and the Arrhenius constant value is 5.87x106 M0.5/s.
Stability Indicating RP-HPLC for Quantification Mangiferin in Extract of Three Species Mango Leaves
Authors: Retnaningtyas Yuni , Kristiningrum Nia , Renggani Hidayah Dwi , Sary Indah Purnama 
Published: May 2020

The stability indication of Reversed Phase-High Performance Liquid Chromatography (RP-HPLC) method was validated for quantitative determination of mangiferin on three species mango leaves (Mangifera odorata Griff, Mangifera foetida Lour, and Mangifera indica L.). The samples were extracted by maseration method using methanol and concentrated using rotary evaporator. The method carried out on stationary phase a purospher RP-18 endcapped (25 cm × 4.6 mm i.d., 5 µm) column with a mobile phase consisting of methanol: phosphoric acid 0.1% (v/v) (31:69); flow rate:0.8 mL/min; solvent methanol, detection was carried out at 258 nm. The analytical performace this measurement is good with the value of linearity (r2=0.998), precision (%RSD=0.649%), and accuration (10.67%). The forced degradation studies were carried out according to the International Conference on Harmonization (ICH) guidelines. The results indicating that the complete separation between degradation products and mangiferin peak occured. The degradation limit of mangiferin 5–20% (according to the guideline of ICH) except in basic condition (100%). The method was succesful applied to determine of the mangiferin in pakel (Mangifera foetida), kweni (Mangifera indica) and kopyor (Mangifera odorata) extract. The mangiferin content was obtained are pakel (9.95%), kopyor (7.40%) and kweni (Mangifera odorata) (2.49%) respectively.
Primary PCI in COVID-19 Pandemic: Be Cautious, It Might Reveal Itself Later
Authors: Parama Arief Luthfi , Rifanda Dmitri , Widodo Wishnu Aditya , Ruslim Daniel 
Published: May 2020

Background: Acute ST-segment–elevation myocardial infarction (STEMI) is a disease of high mortality and morbidity, and primary percutaneous coronary intervention (PPCI) is the preferred therapy for patient in golden period or with hemodynamic instability.1,2 Currently the world has been declared under COVID-19 (coronavirus disease 2019) pandemic by the World Health Organization (WHO).3 Signs and symptoms of COVID-19 patients can mimic acute decompensated heart failure, or induce acute cardiovascular problem.3 Screening is key, but there are conditions where physicians might miss positive COVID-19 cases, especially in critical cardiovascular emergency.
Case Illustration: A 60-year old male came to emergency room with breathlessness and chest pain 8 hours prior. He was diagnosed as acute inferior STEMI with acute lung edema and cardiogenic shock (KILLIP IV, acute heart failure wet and cold). COVID-19 screening was negative. Patient underwent PPCI, found to have total occlusion of right coronary artery (RCA) with thrombus and tight stenosis in left coronary artery (LAD). Successful PPCI to RCA was performed with TIMI 3 flow result, and hemodynamic improved. Ten hours after PPCI, hemodynamic deteriorated and peripheral oxygen saturation dropped. Patient was intubated and put on ventilator. Repeated chest X-Ray and thoracic CT showed lung condition has abruptly worsened – with ground glass opacity (GGO) found. His condition worsened quickly, and family agreed to a do not resuscitate (DNR) consent.
Conclusion: Acute cardiovascular condition in COVID-19 Pandemics represent big challenges, especially in early diagnostic and cardiovascular intervention decision. We were presenting a case where signs and symptoms of COVID-19 might appear later. Therefore, in this pandemic era every emergency cardiovascular intervention with signs of respiratory problem should be performed as if patient was a positive COVID-19 case.
COVID 19 with Cardiac Injury Complication, A case Report
Authors: Saus Puti Sarah , Hanafy Dicky , Barack Rossana 
Published: May 2020

Background : The Corona virus Disease COVID-19 have been independently associated with the cause of pneumonia and acute respiratory distress syndrome with high risk of mortality. Mounting evidence substantiates the presence of cardiac injury in patients with COVID-19. Although a recent study reported that 12% of patients had COVID-19 associated acute cardiac injury.
Case presentation : A 38 year old male was admitted with pneumonia and cardiac symptoms. He was genetically confirmed as COVID-19 by swab PCR testing, 1 week after admission. He also had elevated CKMB and Hs troponin T level, high Ferritin level, CRP, lymphopenia, and a slight increase in N/L ratio. Chest radiography showed bilateral pneumonia. The patient was confirmed to the diagnosis of Myocardial injury. After receiving tocilizumab and immunoglobulin, his condition improved gradually with the declining laboratory inflammation marker, but there was a secondary infection with an increased of leucocyte and worsen chest radiography, escalating antibiotic and metilprednisolon was given, the patient gradually improving.
Conclusion : COVID-19 patients may develop cardiac complication such as cardiac injury or myocarditis, and this is our first case of COVID-19 infection complicated with cardiac injury.
Cardiomyopathy in COVID-19 Survivors: Mechanism, Management, and Prevention
Authors: Sukmawan Renan 
Published: May 2020

Coronavirus disease (COVID-19) caused by infection of SARS-CoV-2 as of April 2020 has been confirmed in more than 2.3 million people, with more than 150 thousands deaths across the globe. It has been known that COVID-19 patients with underlying cardiovascular diseases and its risks including: hypertension, diabetes, coronary artery disease, and cerebrovascular diseases may develop more severe respiratory track symptoms requiring intensive care. Some patients may presenting with myocarditis or acute cardiomyopathy, which has high mortality and morbidity. There was also evidence of myocardial Injury with an increase of troponin in one-third of those infected by covid-19. It is conceivable that among those who recover from COVID-19 infection, there is a risk of developing further cardiomypathy once the pandemic receding in the future. It is important to pay attention to this survivor group since the pandemic may be lasting for longer period. Optimal medical treatment and comprehensive prevention should be taken to manage those high risk patients of developing cardiomyopathy during hospital care as well post discharge. These includes provide best available COVID-19 drugs, cardiovascular medications, and social preventive measures.
Tantangan Penatalaksanaan STEMI di Pandemi Covid-19
Authors: Ng Sunanto , Juzar Dafsah Arifa 
Published: May 2020

The necessity of timely management of ST-elevation myocardial infarction (STEMI) is now disrupted by the Covid-19 pandemic. This paper discussed the challenge to manage STEMI in Indonesia due to Covid-19. It also discussed the alternative strategies for solution. Challenge can occur in term of the healthcare safety as well as STEMI patient safety. Healthcare safety potentially impaired by the problem of STEMI mimicry due to cardiovascular complication of Covid-10, inaccuracy of Covid-19 screening, lack of effective personal protection equipment for the healthcare and appropriate catheterisation laboratory to anticipate virus contamination. The safety of STEMI patient is potentially impaired due to prolonged ischemia time, and the risk of cross-infection. Solution for this challenge should include mass screening, rapid and accurate test to rule-out Covid-19, dual system of hospital units - Covid and non-Covid, and algorithm for triage patients with STEMI and Covid-19.
Mobitz Type II Second-Degree Atrioventricular Block in a Pilot : To Pace or Not to Pace?
Authors: Salim Stephanie , Raharjo Sunu Budhi , Hermanto Dony Yugo , Hanafy Dicky Armein , Yuniadi Yoga , Salim Stephanie , Raharjo Sunu Budhi , Hermanto Dony Yugo , Hanafy Dicky Armein , Yuniadi Yoga 
Published: May 2020

Background: Atrioventricular (AV) block is a threatening condition that caused sudden loss of consciousness and death, notably if happened to aircraft pilot will compromise the reliability of flight operations and safety. Cardiac arrhythmia is well known as one of the main disqualifier for loss of flying license, and discriminating between benign and potentially significant rhythm abnormalities remains a challenge. The present case describes the electrophysiological feature of a high-grade AV block in an aircraft pilot.
Case illustration: A 60-year-old male worked as commercial aircraft pilot presented with asymptomatic high-grade AV block during inflight Holter monitoring. He had never experienced any remarkable symptoms nor history of near syncope, but had a history of percutaneous coronary intervention (PCI) with one stent at left circumflex (LCx) coronary artery. Electrophysiology (EP) study revealed AH interval of 105 ms, HV interval of 50 ms, AV node effective refractory period of 280 ms and Weckenbach point of 330 ms, suggesting a normal EP study. Stimulation with atrial pacing and ATP showed prolongation of AH interval without changes in HV interval, showing the presence of a supra-Hisian AV node dysfunction. The highly demanding physiological environment in aircraft elucidate the likelihood of vagotonic cause of his condition and pacemaker implantation was not warranted.
Conclusion: Atrioventricular (AV) block is an AV conduction disorder that can manifests in various symptoms and severity. Electrophysiology study is considered as a modality to locate the site of block that allows the avoidance of unnecessary permanent pacing and the appropriate prophylactic pacing.
Transient ischemic dilation as a diagnostic marker in myocardial perfusion SPECT protocols: a systematic review and meta-analysis
Authors: Namiranian Nasim , Emami Mahmood , Naghedi Aryan , Razavi-Ratki Seid Kazem 
Published: May 2020

Abstract
Background: Transient ischemic dilation (TID) measures left ventricle (LV) volume changes which can be associated with combination of myocardial and endocardial ischemia. Various stress methods, single photon emission computerized tomography (SPECT) imaging protocol, camera and software incite controversy on TID cut off. The purpose of this study was to evaluate the TID ratio in detection of coronary artery disease (CAD) categories in a systematic review and meta-analysis. Method: We conducted a systematic search of electronic databases (PubMed, Scopus, Embase and Web of Science) up to 1 January 2017. The reference lists of all included studies were searched for a higher accuracy. The search strategy was according a defined PICO as P: none, I: Transient ischemic dilation, O: Coronary Artery Diseases, C: Angiographies. Statistical analysis was done by Comprehensive meta-analysis software version 2 (CMA-2).
Result: After study selection process, 7 studies were selected for data extraction. TID was studied from 1987. The sample size of included studies ranged between 86 and 545. The mean age of included patients varied between 58 and 69 years old. Ranges of TID in CAD categories were excluded. The pooled estimates of TID in single and dual pharmacological stress test in three CAD categories were calculated.
Conclusion: Our findings show that more studies are needed to compare the TID variability. Although in this study meta-analysis was done and TID was summarized from studies but the software differences were ignored.
Effect of Remote Ischemic Postconditioning on miRNA-145 and Troponin I levels in STEMI patients undergoing primary percutaneous coronary intervention
Authors: Permatasari Pradita Diah , Fadil Muhammad , Syafri Masrul 
Published: May 2020

Background: Primary Percutaneous Coronary Intervention Procedure (PPCI) results in reperfusion injury which will result in more extensive infarction. Remote Ischemic Postconditioning (RIPC) is a protective strategy to reduce the increase in the area of ??infarction. miRNA-145 also plays a role in the protective effect of IPC and RIPC.

Research Methods: This study uses a pre and post test approach only with control group design with experimental research designs. Data is taken at the Integrated Heart Services Installation RSUP Dr. M. Djamil Padang from July to November 2019, 40 patients with ST-segment elevation myocardial infarction (STEMI) performed RIPC. Bivariate analysis was performed to determine differences in levels of miRNA-145 and troponin I in STEMI patients underwent PPCI with and without RIPC using the Wilcoxon test and the Mann Whitney test.

Results:A total of 40 patients who underwent the PPCI procedure were divided into two groups PPCI + RIPC (n = 20) and PPCI without RIPC (n = 20). There were no significant differences in the basic characteristics between the two groups. There were no significant difference in escalation of median expression of miRNA-145 in PPCI+ RIPC [pre test 36.33 (27.44-52.39), post test 34.83 (27.65-65.26), p = 0.765] compared to PPCI without RIPC [pre test 31.66 (26.31-43.28), post test 33.43 (26.83-64.97), p = 0.765]. There were an increase in median troponin I levels in both groups, PPCI+ RIPC [pretest 4,104.70 (67.30-40,000.00), post test 30,448.50 (120.00-16.3192.20), p = 0.001] and PPCI without RIPC [pretest 826.50 (17.00-48.259.00), post test 42.784.50 (2,119.00-162.897.00), p = <0.001].

Conclusion:There were no significant difference in median expression of miRNA-145 in STEMI patients before and after (48 hours) underwent PPCI+RIPC and PPCI without RIPC. There were a significant difference in median levels of troponin I in STEMI patients before and after (48 hours) underwent PPCI+RIPC and PPCI without RIPC.
Keywords: Remote Ischemic Postconditioning, miRNA-145, troponin I
Deteksi dan Penanganan Awal Miokarditis dan Miokarditis Fulminan
Authors: Nauli Siti Elkana , Prameswari Hawani Sasmaya 
Published: May 2020

Miokarditis umumnya terjadi akibat infeksi sistemik dari virus yang bersifat kardiotropik. Pada kondisi miokarditis akut ini dapat menyebabkan gangguan hemodinamik atau aritmia letal. Studi terbaru menunjukkan tatalaksana miokarditis terkait penyebab ditambah dengan “guideline directed medical care” akan memberi keluaran yang baik. Presentasi klinis miokarditis beragam dari yang tidak terlalu berat sampai dengan syok kardiogenik. Dengan perkembangan terapi saat ini, bantuan sirkulasi extracorporeal membrane oxygenation (ECMO) dan deteksi dini miokarditis fulminan, maka miokarditis dapat tertangani dengan baik. Dugaan miokarditis fulminan pada COVID-19 telah dilaporkan pada beberapa laporan kasus namun belum ada bukti patologi yang telah terkonfirmasi dari spesimen miokard adanya keterlibatan virus pada miokarditis COVID-19. Pada kasus dengan gambaran critical ill didapatkan tanda dan bukti peningkatan biomarker kerusakan miokard (cTn) dan peningkatan biomarker akibat stress dinding ventrikel kiri (BNP atau NTproBNP). Pada beberapa kasus, pemberian imunosupresan dan monitoring yang baik dapat meningkatkan peluang remisi.
Kata kunci : Miokarditis, fulminan, COVID 19