bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19: Mental and Social Health-Related Complaints among Children and Adolescents in Nigeria: Parents’/Caregivers’ Perception – An Online Survey
Authors: Briggs Datonye Christopher , Kattey Kattey Amos 
Published: October 2020

Aim: This survey aimed to highlight the mental and social health-related complaints of children and adolescents during the lockdown in Nigeria.
Study Design: Descriptive cross-sectional.
Place and Duration of Study: Respondents from all six geopolitical zones in Nigeria, from May 9 to June 8, 2020.Nigeria.
Methodology: A snowball sampling technique was used to recruit 260 respondents, consisting of parents/caregivers of children 18 years and below from states affected by the lockdown. An online self-administered questionnaire was used to collect data. Logistic regression analysis was done on mental health-related complaints (dependent variables), with participation in the radio/TV sessions, presence of computer at home, access to the internet, and income-level of parents as independent variables. Adjusted odds ratios with 95% confidence intervals were calculated.
Results: The median age of respondents was 38 years (with an interquartile range of 9); 155 (59.7%) were females, 239 (91.9%) married, 167 (64.2%) had tertiary education, 83 (31.9%) were low-income earners, 202 (77.7%) had computer devices at home, 243 (93.5%) had internet access at home. Logistic regression revealed that children who participated in the radio/TV sessions were more likely to complain of being bored; and children without internet access at home were more likely to complain of being unhappy, express anxiety/fear and show signs of stress. However, 113 (43.4%) agreed their children learnt a new skill, and 159 (61.1%) agreed there was increased family bonding during the COVID-19 lockdown.
Conclusion: The pandemic threatens the mental and social wellbeing of Nigerian children. Policymakers must put in place measures that address factors which increase the likelihood of mental and social health-related complaints among children by improving access to the internet, subsidizing costs and developing child-focused mental health services with new strategies to reach those already affected.
Genotype x Environment Interaction and Stability Analysis in Okra [Abelmoschus esculentus (L.) Moench] in Cameroon
Authors: Célestin Dabandata , Bille Ngalle Hermine , Armand Nsimi Mva , Zenabou Ndiang , Constant Likeng L. I. Ngue Bénoit- , Bell Joseph Martin 
Published: October 2020

A study was conducted to assess genotype x environment interaction and also to determine stability of okra (Abelmoschus esculentus L. Moench) genotypes for nine traits in Cameroon. Eight okra genotypes (including five parents of Cameroon and three exotics) were evaluated across three different locations (Dibang, Yagoua and Yaounde) using a randomized complete block design (RCBD) with three replications. Each plot consisted of three rows of six plants each. Genotype x environment interaction has been evaluated using SAS Software. There was considerable variation for all traits studied among both genotypes and environments. Five different methods of stability analysis have been used for the comparison of the genotypes and also to determine the most suitable stability parameter of okra. The stability in relation to the characters is independent of the genotypes. A total correspondence (r=1) exist between the general mean and the Pi performance for characters such as 50 % flowering and the fruit peduncle length. For, the procedure of Lin and Binns appeared to be more of a genotype performance measure, rather than a stability measure. The Wricke’s and Shukla’s procedures of stability statistic showed the highest significant positive correlation (P<0.01) with the majority of the studied character. That makes these procedures equivalent for ranking purposes.
A Review of Nanofluids Synthesis, Factors Influencing Their Thermophysical Properties and Applications
Authors: Okello John A. , Mutuku Winifred N. , Oyem Anselm O. 
Published: October 2020

Heat-generating equipment (such as transformers, computer microchips, car engines, nuclear reactors, etc.) requires an efficient cooling mechanism to safeguard them from thermal degradation and to enhance their life span. The use of Nanofluids as opposed to conventional heat transfer fluids in their cooling system is to ensure that they are properly cooled. Nanofluids display superior thermal properties and they are synthesized from nanosized materials such as metals ((Copper (Cu), Silver (Ag), Nickel (Ni), and Gold (Au)), metal oxides (( Aluminum oxide (Al2O3), Cupric oxide (CuO), Magnesium oxide (MgO), Zinc oxide (ZnO), Silica (SiO2), Iron (III) oxide (Fe2O3), and Titania (TiO2)), metal carbide (such as Silicon carbide (SiC)), metal nitride (such as Aluminium nitride (AIN)), or Carbon materials ((Carbon nanotubes (CNTs), Multi-wall carbon nanotubes (MWCNTs), diamond, and graphite)) suspended in base fluids (such as water, ethylene glycol, engine oil, transformer oil, vegetable oil, kerosene, toluene, etc.). The current review explores methods used in the synthesis of nanofluids (One-step method, Two-step method, Solvothermal/Hydrothermal process), factors influencing their thermophysical properties (Particle volume concentration, pH, particle size, particle shape, particle material, base fluid material, temperature, shear rate, and surfactants) and their applications (Heat transfer applications, automotive applications, biomedical applications, electronic applications, Nano-based microbial fuel cells, and Nano-based brake fluids).
Compound Handling Automation: An Error Proof Solution in Eliminating Mold Misprocessing
Authors: Padilla Ernani D. , Birog Emmanuel P. 
Published: October 2020

This paper aims to identify and eliminate the weaknesses of the epoxy mold compound (EMC) thawing process that contributes to mold misprocessing occurrence such as wrong mold compound, under thawed or expired mold compound.
Creation of automation solutions addressing high risk areas such as barcoding of compound traceability, auto-locking system of thawing cabinet and thawing room access, automated map of compound status and upgrade of lot transaction system to link with EMC status and identity was implemented. Collectively this makes the process error proof from wrong judgement or negligence from human dependent activities.
The project was able to eliminate occurrence of possible mold misprocessing related to EMC thawing and serves as cost avoidance due to potential lots affected.
Preseptal Cellulitis: 13 Years Review in a Tertiary Hospital South-Eastern Nigeria
Authors: Apakama Akunne I. , Uzozie Chukwudi C. , Nnubia Chinasa A. 
Published: October 2020

Objectives: To determine the epidemiology and management outcome of preseptal cellulitis seen at a tertiary eye hospital within a period of 13 years.
Materials and Methods: The case files of all patients seen with preseptal cellulitis from 2005 to 2017 were reviewed. The information obtained included the patients’ demography, presenting symptoms and signs, research, treatment, outcome, complications and follow-up.
Results: Of the 123 patients with preseptal cellulitis reported on the study, 66 were males and 57 females. In a range of 0 to 80 years old, the mean age was 19 years. The commonest predisposing factor was trauma (20.3%) followed by upper respiratory tract infection (11.4%). Progression to orbital cellulitis was seen in 11.4% of the patients.
Conclusion: Preseptal cellulitis is not uncommon in adults as seen in previous studies. Trauma is now more common than sinusitis as a predisposing factor. Despite oral antibiotic therapy some cases may progress to orbital cellulitis.
Recent Progress in Artificial Muscles for Interactive Soft Robotics
Authors: Wang Jiangxin , Gao Dace , Lee Pooi See 
Published: October 2020

AbstractArtificial muscles are the core components of the smart and interactive soft robotic systems, providing the capabilities in shape morphing, manipulation, and mobility. Intense research efforts in the development of artificial muscles are based on the dielectric elastomer actuators, pneumatic actuators, electrochemical actuators, soft magnetic actuators, and stimulus responsive polymers. Recent progress has presented artificial muscles with impressive specific power output exceeding that of the natural muscles, dexterous shape morphing behavior that can be programmed and reconfigured, and exceptional high maneuverability to traverse surfaces with obstacles and different textures. Here, a succinct and critical summary is provided on the materials and strategies that have contributed to the important advancement of the artificial muscles in recent research. On that basis, the exciting opportunities are discussed in the integration of soft electronic devices with artificial muscles to enable smart and interactive soft robotic systems.
Combinatorial Strategy for Studying Biochemical Pathways in Double Emulsion Templated Cell‐Sized Compartments
Authors: dos Santos Elena C. , Belluati Andrea , Necula Danut , Scherrer Dominik , Meyer Claire E. , Wehr Riccardo P. , Lörtscher Emanuel , Palivan Cornelia G. , Meier Wolfgang 
Published: October 2020

AbstractCells rely upon producing enzymes at precise rates and stoichiometry for maximizing functionalities. The reasons for this optimal control are unknown, primarily because of the interconnectivity of the enzymatic cascade effects within multi‐step pathways. Here, an elegant strategy for studying such behavior, by controlling segregation/combination of enzymes/metabolites in synthetic cell‐sized compartments, while preserving vital cellular elements is presented. Therefore, compartments shaped into polymer GUVs are developed, producing via high‐precision double‐emulsion microfluidics that enable: i) tight control over the absolute and relative enzymatic contents inside the GUVs, reaching nearly 100% encapsulation and co‐encapsulation efficiencies, and ii) functional reconstitution of biopores and membrane proteins in the GUVs polymeric membrane, thus supporting in situ reactions. GUVs equipped with biopores/membrane proteins and loaded with one or more enzymes are arranged in a variety of combinations that allow the study of a three‐step cascade in multiple topologies. Due to the spatiotemporal control provided, optimum conditions for decreasing the accumulation of inhibitors are unveiled, and benefited from reactive intermediates to maximize the overall cascade efficiency in compartments. The non‐system‐specific feature of the novel strategy makes this system an ideal candidate for the development of new synthetic routes as well as for screening natural and more complex pathways.
Rhodium(III)‐Catalyzed Annulation of 2‐Arylimidazo[1,2‐a]pyridines with Maleimides: Synthesis of 1H‐Benzo[e]pyrido[1′,2′:1,2]imidazo[4,5‐g]isoindole‐1,3(2H)‐Diones and their Photophysical Studies
Authors: Shinde Vikki N. , Kanchan Roy Tapta , Jaspal Sonam , Nipate Dhananjay S. , Meena Neha , Rangan Krishnan , Kumar Dalip , Kumar Anil 
Published: October 2020

AbstractRhodium(III)‐catalyzed dehydrogenative annulation of 2‐aryl‐imidazo[1,2‐a]pyridines with maleimides is described. The reaction afforded 1H‐benzo[e]pyrido[1′,2′:1,2]imidazo[4,5‐g]isoindole‐1,3(2H)‐diones in high yields with wide range of functional group tolerance. The reaction proceeds through Rh(III)‐catalyzed C−H bond activation, followed by maleimide insertion and intramolecular cyclization. Photophysical properties of 1H‐benzo[e]pyrido[1′,2′:1,2]imidazo[4,5‐g]isoindole‐1,3(2H)‐diones were studied with UV‐visible and fluorescence spectroscopy and validated by quantum chemical calculations. All the annulated products showed large Stokes shift values with emission in the range of 530–618 nm, and moderate to high quantum yields.magnified image
Lymphedema distichiasis syndrome may be caused by FOXC2 promoter‐enhancer dissociation and disruption of a topological associated domain
Authors: Wallis Mathew , Pope‐Couston Rachel , Mansour Julia , Amor David J. , Tang Paisu , Stock‐Myer Sharyn 
Published: October 2020

AbstractLymphedema distichiasis syndrome (LDS) is a rare autosomal dominant condition characterized by lower limb lymphedema, distichiasis, and variable additional features. LDS is usually caused by heterozygous sequence variants in the FOXC2 gene located at 16q24, but in one previous instance LDS has resulted from a balanced reciprocal translocation with a breakpoint at 16q24, 120 kb distal to the FOXC2 gene suggesting a position effect. Here, we describe a second family with LDS caused by a translocation involving 16q24. The family were ascertained after detection of a paternally inherited balanced reciprocal translocation t(16;22)(q24;q13.1) in a pregnancy complicated by severe fetal hydrops. There was a past history of multiple miscarriages in the father's family, and a personal and family history of lymphedema and distichiasis, consistent with the diagnosis of LDS. Using whole genome amplified DNA from single sperm of the male proband, bead array analysis demonstrated that the FOXC2 gene was intact and the chromosome 16 breakpoint mapped to the same region 120Kb distal to the FOXC2 gene. This case highlights the clinical consequences that can arise from a translocation of genomic material without dosage imbalance, and that it is increasingly feasible to predict and characterize possible effects with improved access to molecular techniques.
Point‐of‐care lung ultrasound in the assessment of patients with COVID‐19: A tutorial
Authors: Cid Ximena , Wang Andrew , Heiberg Johan , Canty David , Royse Colin , Li Xiaoqiang , El‐Ansary Doa , Yang Yang , Haji Kavi , Haji Darsim , Denault Andre , Tivendale Lynda , Brooks Kyle , Hu Xiaobo , Royse Alistair 
Published: October 2020

AbstractThe adoption of point‐of‐care lung ultrasound for both suspected and confirmed COVID‐19 patients highlights the issues of accessibility to ultrasound training and equipment. Lung ultrasound is more sensitive than chest radiography in detecting viral pneumonitis and preferred over computed tomography for reasons including its portability, reduced healthcare worker exposure and repeatability. The main lung ultrasound findings in COVID‐19 patients are interstitial syndrome, irregular pleural line and subpleural consolidations. Consolidations are most likely found in critical patients in need of ventilatory support. Hence, lung ultrasound may be used to timely triage patients who may have evolving pneumonitis. Other respiratory pathology that may be detected by lung ultrasound includes pulmonary oedema, pneumothorax, consolidation and large effusion. A key barrier to incorporate lung ultrasound in the assessment of COVID‐19 patients is adequate decontamination of ultrasound equipment to avoid viral spread. This tutorial provides a practical method to learn lung ultrasound and a cost‐effective method of preventing contamination of ultrasound equipment and a practical method for performing and interpreting lung ultrasound.
autodE: Automated Calculation of Reaction Energy Profiles— Application to Organic and Organometallic Reactions
Authors: Young Tom A. , Silcock Joseph J. , Sterling Alistair J. , Duarte Fernanda 
Published: October 2020

AbstractCalculating reaction energy profiles to aid in mechanistic elucidation has long been the domain of the expert computational chemist. Here, we introduceautodE(https://github.com/duartegroup/autodE), an open‐source Python package capable of locating transition states (TSs) and minima and delivering a full reaction energy profile from 1D or 2D chemical representations.autodEis broadly applicable to study organic and organometallic reaction classes, including addition, substitution, elimination, migratory insertion, oxidative addition, and reductive elimination; it accounts for conformational sampling of both minima and TSs and is compatible with many electronic structure packages. The general applicability ofautodEis demonstrated in complex multi‐step reactions, including cobalt‐ and rhodium‐catalyzed hydroformylation and an Ireland–Claisen rearrangement.
Reduction of π‐Expanded Cyclooctatetraene with Lithium: Stabilization of the Tetra‐Anion through Internal Li+ Coordination
Authors: Zhou Zheng , Zhu Yikun , Wei Zheng , Bergner John , Neiß Christian , Doloczki Susanne , Görling Andreas , Kivala Milan , Petrukhina Marina A. 
Published: October 2020

AbstractThe chemical reduction of a π‐expanded polycyclic framework comprising a cyclooctatetraene moiety, octaphenyltetrabenzocyclooctatetraene, with lithium metal readily affords the corresponding tetra‐anion instead of the expected aromatic dianion. As revealed by X‐ray crystallography, the highly contorted tetra‐anion is stabilized by coordination of two internally bound Li+, while two external cations remain solvent separated. The variable‐temperature 7Li NMR spectra in THF confirm the presence of three types of Li+ ions and clearly differentiate internal binding, consistent with the crystal structure. Density‐functional theory calculations suggest that the formation of the highly charged tetra‐reduced carbanion is stabilized through Li+ coordination under the applied experimental conditions.
Rubber's dissipated energy quantification used in vibratory insulation and protection systems
Authors: Chiter Ammar 
Published: October 2020

AbstractIn vibratory protection and insulation systems, the major problem consist to choose suitable passive elements (spring, damper, others), which are inserted between the resonator and the exciter which have the role of preventing or reducing the transmission of dynamic forces. This work consists of characterizing a synthetic rubber (SR) sample of hollow circular shape (design requirement) by determining the coefficient of energy dissipation at an average ambient temperature of 20°C with a humidity of 25%. The mechanical load and discharge tests make it possible to draw hysteresis curves through which the dissipation coefficient will be determined, the load values is between 500 and 1000 N, with 30, 60, and 90 mm/min loading speeds and a number of cycles 2, 3, and 5, these values have been chosen so as not to cause the effect of cyclic hardening and softening and also to take into consideration, that the vibration limits movement at 3 cycles, which makes this test different from other tests such as fatigue. The processing of different curves, allows to determine energy dissipation coefficient of rubber specimen and also to examine its variation as a function of load, loading speed, and number of cycles; it is possible to determine other characteristics from this coefficient, such as, damping ratio, dynamic amplification factor, and so on, necessary to study efficiency of protection systems, design, and manufacture, based on the curve of transmissibility of dynamic forces to evaluate performance rubber conditions use.
Influence of Nitrogen to Phosphorus Ratio and CO2 Concentration on Lipids Accumulation of Scenedesmus dimorphus for Bioenergy Production and CO2 Biofixation
Authors: Omar Faruque Mohammed , Ilyas Muhammad , Mozahar Hossain Mohammad , Abdur Razzak Shaikh 
Published: October 2020

AbstractThe potential of Scenedesmus dimorphus microalgae for CO2 biofixation and lipid biosynthesis for bioenergy applications was evaluated in this study. Batch experiments were conducted using synthetic tertiary municipal wastewater samples at several nitrogen to phosphorus (NP) ratios (1 : 1 to 8 : 1) and CO2 concentrations (∼0%, 2%, 4%, and 6% CO2 in supplied air). Scenedesmus dimorphus was cultivated for 25 days and the growth is highly dependent on the CO2 concentration and the NP ratio. An NP ratio of 2 : 1 produces a biomass yield of 733 mg/L when the microalga culture was supplied with air enriched with 2% CO2. The maximum CO2 biofixation rate of 49.6 mg L−1 d−1 is at an NP ratio of 8 : 1 with 4% CO2. A colorimetric technique depending on sulpho‐phospho‐vanillin (SPV) was utilized for the determination of the intracellular lipid content. The highest lipid content of 31.6% as the dry weight of the biomass is at an NP ratio of 1 : 1 and 6% CO2. These results indicate that supplementation of suitable CO2 with favorable NP ratio has a considerable effect on lipid accumulation in the microalgae Scenedesmus dimorphus biomass.
Mapping the environmental and techno‐economic potential of biojet fuel production from biomass residues in Brazil
Authors: Cervi Walter Rossi , Lamparelli Rubens Augusto Camargo , Gallo Bruna Cristina , de Oliveira Bordonal Ricardo , Seabra Joaquim Eugênio Abel , Junginger Martin , van der Hilst Floor 
Published: October 2020

AbstractThis study assesses the environmental potential of crop residues and the techno‐economic potential of biojet fuel (BJF) production in Brazil. Different production routes are evaluated from two types of biomass residues (sugarcane straw and eucalyptus harvest residue), and four different technological pathways (alcohol to jet, Fischer–Tropsch, hydrothermal liquefaction and pyrolysis). The environmental potential of biomass residues is determined utilizing spatio‐temporal projections of land‐use change in Brazil and by explicitly modeling the erosion risk and the soil organic carbon (SOC) balance spatially. The assessment of the techno‐economic potential of BJF production from the environmental potential of sugarcane straw (SCS) and eucalyptus harvest residues (EHRs) considers the BJF total costs, which result from a summation of biomass residue recovery costs, BJF conversion costs, and BJF transportation costs. These BJF total costs are compared with the range of fossil jet fuel prices at Brazilian airports to quantify the techno‐economic potential. The environmental potential of biomass residues varies from 70 Mt in 2015 to 102 Mt in 2030, with SCS being highly constrained by SOC, whereas EHRs are more constrained by the high erosion risk. These quantities can generate a techno‐economic BJF potential ranging from 0.45 EJ in 2015 (46 US$/GJ – 65 US$/GJ) to 0.67 EJ in 2030 (19 US$/GJ – 65 US$/GJ). In 2030, several BJF production routes can be competitive with fossil jet fuel prices. The northeast and southeast regions have the highest potential, especially in 2030. © 2020 The Authors. Biofuels, Bioproducts, and Biorefining published by Society of Chemical Industry and John Wiley & Sons, Ltd.
The prognostic value of circRNAs for gastric cancer: A systematic review and meta‐analysis
Authors: Chen Hui , Liang Chengtong , Wang Xuechun , Liu Yu , Yang Zhanjun , Shen Ming , Han Chongxu , Ren Chuanli 
Published: October 2020

AbstractGastric cancer is the third leading cause of cancer‐related deaths worldwide. Novel biomarkers circRNAs can play an important role in the development of gastric cancer as oncogenes or tumor suppressor genes. The purpose of this study was to clarify the relationship between the abnormal expression of multiple circRNAs and their prognostic value in gastric cancer patients through a meta‐analysis. We researched articles reporting the relationship between circRNAs and the prognosis of gastric cancer published in PubMed, Cochrane, Embase, Web of Science, Wanfang, CNKI, and VIP databases before 31 December 2019. Thirty‐five articles were selected for the meta‐analysis, involving 3135 gastric cancer patients. The total HR values (95% CI) of OS and DFS related to highly expressed circRNAs that indicated worse prognosis were 1.83 (1.64‐2.03; p < 0.001) and 1.66 (1.33‐2.07; p < 0.001), respectively. The total HR (95% CI) of OS and DFS related to highly expressed circRNAs that indicated better prognosis was 0.54 (0.45‐0.66; p < 0.001) and 0.58 (0.43‐0.78; p < 0.001), respectively. Two panels of five circRNAs predicted a more considerable HR value (circ_0009910, hsa_circ_0000467, hsa_circ_0065149, hsa_circ_0081143, and circDLST; and circSMARCA5, circLMTK2, hsa_circ_0001017, hsa_circ_0061276, and circ‐KIAA1244). The results of the meta‐analysis were 2.63 (2.08‐3.33; p < 0.001) and 0.39 (0.27‐0.59; p < 0.001) for OS, respectively. The two panels of dysregulated circRNAs can be considered as more suitable potential prognostic tumor biomarkers in patients with gastric cancer because of their larger HR values.