bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilisation des données administratives pour comprendre la distribution géographique de la détermination des cas
Authors: Yiannakoulias N. , Schopflocher D.P. , Svenson L.W. 
Published: October 2020

Résumé

Nous avons examiné la variabilité géographique de l’information générée à partir de différentes définitions de cas d’asthme infantile, provenant des données administratives sur la santé utilisées en Alberta, au Canada. Notre objectif était de déterminer si les analyses fondées sur différents algorithmes de détermination des cas permettent ou non de définir les groupes géographiques dans la même région que celle sur laquelle porte l’étude. Notre groupe d’étude reposait sur une cohorte fermée d’enfants asthmatiques nés en 1988. Nous avons utilisé une statistique sur l’analyse spatiale pour établir les variations de l’emplacement approximatif des groupes géographiques liés à l’asthme selon différentes définitions de cas. Nos résultats indiquent que l’algorithme de détermination des cas et la source de données n’ont pas une très grande incidence sur les profils géographiques. Par exemple, les asthmatiques identifiés à partir des données sur les réclamations au titre de frais médicaux ont démontré un regroupement semblable à celui des asthmatiques définis à partir des données sur l’hospitalisation et provenant du service d’urgence. Cependant, il faut bien prendre en considération les estimations de la prévalence et de l’incidence et les valider par rapport aux autres sources de données.
Association of obesity with mood and anxiety disorders in the adult general population
Authors: Gadalla T.M. 
Published: October 2020

Abstract

Obesity is a major health concern. It has been implicated as a risk factor for several physical illnesses, functional limitations and poor quality of life. However, while the physical consequences of obesity are well established, the relationship between obesity and mental health is still unclear. This study used data collected in the Canadian Community Health Survey, cycle 3.1 (2005) to examine this relationship in adults 20 to 64 years old. Obesity was significantly associated with mood disorders, but not with anxiety disorders. When adjusting for sex, place of birth, smoking, and functional limitations, all of which were significantly associated with obesity, the odds of obesity remained significantly higher in persons with mood disorders (with or without anxiety disorders). It is still unclear whether the relationship between obesity and depression is causal, and if so, whether obesity causes depression or depression causes obesity. Implications for health care providers and suggestions for future research are discussed.
The comorbidity burden of the treated asthma patient population in British Columbia
Authors: Prosser R. , Carleton B. , Smith A. 
Published: October 2020

Abstract

To date there has been little investigation of the prevalence of comorbid conditions in asthma patients. Using 1996/97 cross-sectional health services administrative data for British Columbia, we compared the prevalence of comorbid conditions in treated adult asthma patients with the general adult population using a standardized comorbidity identification methodology, the Adjusted Clinical Group (ACG) Case-Mix System. We also profiled the comorbidity burden of pediatric asthma patients. Adults with asthma were significantly more likely to have a range of comorbidities, including respiratory infections, allergic rhinitis and 8 high impact/high prevalence chronic conditions (HIHPCCs). One in 4 adults with asthma had depression, the most prevalent HIHPCC. Children with asthma had a lower comorbidity burden than adults, but 12.6% had a stable or unstable chronic medical condition, with the most prevalent HIHPCC also depression. Adults with asthma had a high and complex comorbidity burden, particularly in terms of multiple chronic conditions. We discuss the implications for services planning and delivery.
Heidegger y el despertar: una articulación de su perspectiva del obrar y de la praxis en 1929-1930
Authors: Butierrez Luis Fernando 
Published: October 2020

En este trabajo indagaremos en torno al estatuto de la acción y la praxis en la obra de Heidegger a partir de un análisis de la figura del despertar relativa al aburrimiento profundo, en su trabajo de 1929-1930. Con ello, buscaremos demostrar que las implicancias relativas al actuar, pensar y filosofar allí expuestas, permiten cotejar continuidades y diferencias de tipo fronterizo tanto con sus elaboraciones anteriores, como respecto a su perspectiva posterior a la kehre. Para dar cuenta de ello, primero abordaremos aspectos fundamentales de su interpretación de la filosofía práctica aristotélica y sus reelaboraciones hasta Sein und Zeit.
Two-level cervical disc arthroplasty in patients with Klippel-Feil syndrome: A case report and review of the literature
Authors: Ryu Robert C. , Behrens Phillip H. , Burkert Blake A. , Johnson J. Patrick , Kim Terrence T. 
Published: October 2020

Background:
Klippel-Feil syndrome (KFS) is defined by multiple abnormal segments of the cervical spine with congenital synostosis of two or more cervical vertebrae. KFS patients who demonstrate progressive symptomatic instability and/or neurologic sequelae are traditionally managed with operative decompression and arthrodesis.

Case Description:
A 44-year-old female with chronic neck pain and radiculopathy and a C7-T1 KFS presented with adjacent segment degenerative disc disease at the C5-6 and C6-7 levels. She was successfully managed with a two-level cervical disc arthroplasty (CDA).

Conclusion:
Patients with KFS and disease at two contiguous, adjacent levels (e.g., cervical disc disease) may be safely and effectively managed with two-level CDA.
PENGARUH KECERDASAN EMOSIONAL TERHADAP PRESTASI BELAJAR MATEMATIKA KELAS XII SMAN 1 PAKEL
Authors: Waluyo Adi 
Published: October 2020

Penelitian ini bertujuan untuk mengetahui ada tidaknya pengaruh kecerdasan emosional terhadap prestasi belajar matematika siswa. Penelitian kuantitatif dengan jenis korelasional ini dilaksanakan di SMA Negeri 1 Pakel dengan populasi 134 dan sampel diambil secara Cluster Random Sampling sehingga didapat 1 kelas yaitu kelas XII MIPA 2 +dengan jumlah siswa 34. Pengumpulan data dilakukan dengan angket dan tes yang telah .diuji cobakan di kelas XII IPA-3 dan memenuhi syarat validitas, tingkat kesukaran dan realibilitas. Analisis data menggunakan analisis variansi korelasi linear sederhana dengan uji F. Dari hasil perhitungan analisis variansi korelasi linear sederhana dengan uji F dengan taraf signifikan ? = 0,05 didapat Fhitung = 24,42 dan Ftabel = 4,15. Karena hasil Fhitung &gt; Ftabel maka Ho ditolak. Kesimpulan adalah Ada pengaruh positif kecerdasan emosional terhadap prestasi belajar matematika siswa kelas XII IPA SMA Negeri 1 Pakel Tulungagung Tahun Pelajaran 2018/2019
Pengembangan buku panduan guru berbasis penemuan terbimbing pada materi statistika siswa SMP
Authors: Nasir Ahmad , Nazihah Zuhrotun 
Published: October 2020

<p class="Abstrak">Penelitian pengembangan ini bertujuan untuk menghasilkan produk pengembangan buku panduan guru berbasis penemuan terbimbing pada materi statistika untuk siswa kelas VII SMPN 1 Grati, yang memenuhi kriteria valid, efektif dan praktis. Proses pengembangan menggunakan model pengembangan 4-D, dengan modivikasi 3-D, yaitu tahap <em>define </em>(pendefinisian), <em>design</em> (perancangan), dan <em>development</em> (pengembangan) tanpa tahapan <em>dessiminate </em>(penyebaran). Subjek penelitian ini adalah guru dan siswa kelas VII-D dan kelas VII-G SMPN 1 Grati. Instrumen yang digunakan yaitu: lembar validasi buku panduan guru dan RPP untuk mengukur kevalidan produk, lembar observasi aktivitas guru dan lembar observasi aktivitas siswa untuk mengukur kepraktisan, dan soal tes pembelajaran untuk mengukur keefektifan. Hasil validitas dari buku panduan guru yang ditunjukkan dengan nilai rata-rata sebesar 4,7. Hasil kepraktisan dari buku panduan guru ditunjukkan dengan nilai rata-rata aktivitas guru sebesar 4,9 dan nilai rata-rata aktivitas siswa 4,8. Sedangkan hasil keefektifan produk sebesar 93%. </p>
Yield and seed productivity of pear rootstock forms in the conditions of the steppe zone of the Southern Urals
Authors: Lokhova A. I. , Savin E. Z. , Rusanov A. M. , Mushinskiy A. A. 
Published: October 2020

The article presents the results of studying the diversity of pear rootstock forms in terms of yield and seed productivity. The research was carried out at the experimental sites of the Orenburg Experimental Station of Horticulture and Viticulture of AllRussian Horticultural Institute for Breeding, Agrotechnology and Nursery and the Botanical Garden of the Orenburg State University in 2017-2019, in typical soil and climatic conditions of the Orenburg city. The purpose of the study is to identify pear rootstock forms characterized by high yield and stable seed productivity for use in the future as a seed rootstock. During the research, 15 pear accessions were studied; the planting scheme was 6x4 m. As a result of research, it was found that the rootstock form Temno-zelenaya is characterized by a high yield (40 kg/tree). High seed productivity of more than 6 seeds in one fruit was observed in samples: Vernaya (6.0-6.5 pcs.), SK-1, SK-3 (6.1-7.8 pcs.), SK-2 (7.0-7.5 pcs.), Chang Bai Li (7.4-7.7 pcs.), Semennaya 214 (7.5-7.8 pcs.). It was revealed that the Xiao he Bai Li variety is characterized by the maximum weight of 1000 seeds (65.2 g). Analysis of accessions by seed yield established that a consistently high yield is observed in the varieties Chang Bai Li (2.5-4.2 %), Vernaya (3.96-4.18 %) and forms SK-1 (2.0-3.25%), SK-2 (2.25-2.75 %), SK-3 (1.43-4.0 %). Pear rootstock forms Chang Bai Li, Vernaya, Semennaya 214, SK-1, SK-2, SK-3 were identifi ed, which can be recommended for production testing as seed pear rootstocks for the conditions of the steppe zone of the Southern Urals.
Long-term survival in patients with primary intracranial germ cell tumors treated with surgery, platinum-based chemotherapy, and radiotherapy: a single-institution study
Authors: Shimizu Hiroyuki , Motomura Kazuya , Ohka Fumiharu , Aoki Kosuke , Tanahashi Kuniaki , Hirano Masaki , Chalise Lushun , Nishikawa Tomohide , Yamaguchi Junya , Yoshida Jun , Natsume Atsushi , Wakabayashi Toshihiko 
Published: October 2020

OBJECTIVE
The current study aimed to evaluate the treatment outcomes and toxicities of patients with intracranial germ cell tumors (GCTs).

METHODS
This study retrospectively included 110 consecutive patients (70 patients in the germinomatous group and 40 patients in the nongerminomatous GCT [NGGCT] groups) receiving surgery, platinum-based chemotherapy, and radiotherapy for newly diagnosed primary intracranial GCTs. In the authors’ protocol, patients with GCTs were further divided into the following four groups: the germinomatous group and the NGGCT groups (mature teratoma, intermediate prognosis, or poor prognosis).

RESULTS
The median overall survival (OS) and progression-free survival (PFS) rates of the patients in the germinomatous group were significantly higher than those in the NGGCT group (p < 0.001). The 5-, 10-, and 20-year OS rates in the germinomatous group were 97.1%, 95.7%, and 93.2%, respectively, with a median follow-up of 11.0 years. On the contrary, the 5-, 10-, and 20-year OS rates in the NGGCT group were 67.3%, 63.4%, and 55.4%, respectively. The 5-, 10-, and 20-year PFS rates were 91.4%, 86.6%, and 86.6%, respectively, in the germinomatous group, whereas those of the NGGCT group were approximately 67.4%, 60.2%, and 53.5%, respectively. Based on the four types of classification in our study, the 5-, 10-, and 20-year OS rates in the NGGCT intermediate prognosis group were 78.9%, 71.8%, and 53.8%, respectively. On the contrary, the 3- and 5-year OS rates in the NGGCT poor prognosis group were 42.9% and 34.3%, respectively. Moreover, toxicities with the treatment of intracranial GCTs were found to be tolerable in the present study population. The multivariate survival models for OS in the NGGCT intermediate prognosis and poor prognosis groups demonstrated that only the alpha-fetoprotein status was significantly associated with worsened OS (HR 3.88, 95% CI 1.29–11.66; p = 0.02).

CONCLUSIONS
The authors found that platinum-based chemotherapy and radiotherapy result in favorable survival outcomes in patients with germinomatous GCTs. Clinical outcomes were still unfavorable in the NGGCT intermediate prognosis and poor prognosis groups; therefore, a new protocol that increases the survival rate of patients belonging in both groups should be considered.
Soft tissue density within the foramen magnum, a predictor for surgical intervention in pediatric patients with Chiari malformation type I
Authors: Fuell William , Elwy Reem , Harkey Thomas , Carey Matthew , Albert Gregory W. 
Published: October 2020

OBJECTIVEChiari malformation type I (CMI) is diagnosed as herniation of the cerebellar tonsils by at least 5 mm below the foramen magnum. However, the degree of tonsillar herniation is a poor predictor of the need for decompression surgery. Exploration for an alternative morphological predictor for surgical intervention could provide greater insight into the development of an appropriate treatment plan for these patients. To investigate this issue, the authors calculated the soft tissue density within the foramen magnum as a measure of impaction of the cerebellar tonsils. Soft tissue density within the foramen magnum and degree of tonsillar herniation were then assessed for their correlation with the need for surgical intervention.METHODSThe authors conducted a retrospective, longitudinal chart review of pediatric patients with CMI. Those who had undergone surgical intervention were considered symptomatic and those who had been treated conservatively, as asymptomatic. Soft tissue density was found by dividing the soft tissue occupancy of the foramen magnum (brainstem and cerebellar tonsils) by the total area of the bony foramen magnum. The predictive value of these two measurements for the need of surgery was determined.RESULTSOf the 465 patients seen for CMI at the authors’ institution between July 1, 2011, and May 31, 2017, 80 underwent surgical intervention and 385 were asymptomatic. The average tissue density was significantly greater in the surgical group than in the asymptomatic group (83.3% and 78.6%, respectively, p < 0.0001). The average tonsillar descent for surgical patients was 10.8 mm compared to 9.8 mm for asymptomatic patients (p = 0.140). The point-biserial correlation coefficient was assessed, and soft tissue density was found to positively correlate with the need for surgical intervention (rpb = 0.199, p = 0.0001), whereas tonsillar herniation did not correlate with the need for surgery (rpb = 0.083, p = 0.115). Additionally, the degree of tonsillar herniation did not correlate with soft tissue density (r = 0.09), indicating that soft tissue density is an independent morphological parameter.CONCLUSIONSThe study findings suggest that the need for surgical intervention in CMI patients is positively correlated with increasing soft tissue density within the foramen magnum, whereas the degree of tonsillar herniation did not show a correlation with the need for surgical intervention. Additionally, soft tissue density is a factor independent of the degree of tonsillar herniation. Further investigation of tissue density within the foramen magnum is needed in the hope of discovering a clinically applicable parameter that would indicate a need for surgical intervention in patients with CMI.
Effects of intraoperative liposomal bupivacaine on pain control and opioid use after pediatric Chiari I malformation surgery: an initial experience
Authors: Lu Victor M. , Daniels David J. , Haile Dawit T. , Ahn Edward S. 
Published: October 2020

OBJECTIVEPediatric Chiari I malformation decompression is a common neurosurgical procedure. Liposomal bupivacaine (LB) is a novel formulation that can have an impact on postoperative recovery for particular procedures, but its potential role in pediatric neurosurgery is largely unexplored. The authors sought to describe and assess their initial experience with LB in pediatric Chiari I malformation decompression to better define its potential role as an analgesic agent in a procedure for which the postoperative course is often remarkably painful.METHODSA retrospective review of all pediatric Chiari procedures performed at the authors’ institution between 2018 and 2020 was conducted. Patients were divided into those who were treated with a single intraoperative dose of LB (LB group) and those who were not (control group). Comparisons of total opioid use and pain control were made using chi-square and Wilcoxon rank-sum tests.RESULTSA total of 18 patients were identified, 9 (50%) in the LB group and 9 (50%) in the control group. Overall, there were 13 (72%) female and 5 (28%) male patients with a mean age of 15.9 years. No surgical complications were observed over a mean length of stay of 2.7 days. Within the first 24 hours after surgery, the LB group had significantly lower total opioid use than the control group (17.5 vs 47.9 morphine milligram equivalents, respectively; p = 0.03) as well as lower mean pain scores reported by patients using a 10-point visual analog scale (3.6 vs 5.5 for the LB vs control groups, p = 0.04). However, from the first 24 postoperative hours to discharge, total opioid use (p = 0.51) and mean pain scores (p = 0.09) were statistically comparable between the two groups. There were 2/9 (22%) LB patients versus 0/9 (0%) control patients who did not require opioid analgesia at any point during hospitalization.CONCLUSIONSThe use of a single intraoperative dose of LB in pediatric Chiari I malformation surgery appears to be safe and has the potential to reduce pain scores and opioid use when administered during the first 24 postoperative hours. From that time period to discharge, however, there may be no significant difference in total opioid use or pain scores.
Economic analysis of 90-day return to the emergency room and readmission after elective lumbar spine surgery: a single-center analysis of 5444 patients
Authors: Wiley Marcel R. , Carreon Leah Y. , Djurasovic Mladen , Glassman Steven D. , Khalil Yehia H. , Kannapel Michelle , Gum Jeffrey L. 
Published: October 2020

OBJECTIVEIn the future, payers may not cover unplanned 90-day emergency room (ER) visits or readmissions after elective lumbar spine surgery. Prior studies using large administrative databases lack granularity and/or use a proxy for actual cost. The purpose of this study was to identify risk factors and subsequent costs associated with 90-day ER visits and readmissions after elective lumbar spine surgery.METHODSA prospective, multisurgeon, single-center electronic medical record was queried for elective lumbar spine fusion surgeries from 2013 to 2017. Predictive models were created for 90-day ER visits and readmissions.RESULTSOf 5444 patients, 729 (13%) returned to the ER, most often for pain (n = 213, 29%). Predictors of an ER visit were prior ER visit (OR 2.5), underserved zip code (OR 1.4), and number of chronic medical conditions (OR 1.4). In total, 421 (8%) patients were readmitted, most frequently for wound infection (n = 123, 2%), exacerbation of chronic obstructive pulmonary disease (n = 24, 0.4%), and sepsis (n = 23, 0.4%). Predictors for readmission were prior ER visit (OR 1.96), multiple chronic conditions (OR 1.69), obesity (nonobese, OR 0.49), race (African American, OR 1.43), admission status (ER admission, OR 2.29), and elevated hemoglobin A1c (OR 1.80). The mean direct hospital cost for an ER visit was $1971, with 75% of visits costing less than $1890, and the average readmission cost was $7347, with 75% of readmissions costing less than $8820. Over the 5-year study period, the cost to the institution for 90-day return ER visits was $5.1 million.CONCLUSIONSRisk factors for 90-day ER visit and readmission after elective lumbar spine surgery include medical comorbidities and socioeconomic factors. Proper patient counseling, appropriate postoperative pain management, and optimization of modifiable risk factors prior to surgery are areas to focus future efforts to lower 90-day ER visits and readmissions and reduce healthcare costs.
Does the Global Alignment and Proportion score overestimate mechanical complications after adult spinal deformity correction?
Authors: Baum Griffin R. , Ha Alex S. , Cerpa Meghan , Zuckerman Scott L. , Lin James D. , Menger Richard P. , Osorio Joseph A. , Morr Simon , Leung Eric , Lehman Ronald A. , Sardar Zeeshan , Lenke Lawrence G. 
Published: October 2020

OBJECTIVEThe goal of this study was to validate the Global Alignment and Proportion (GAP) score in a cohort of patients undergoing adult spinal deformity (ASD) surgery. The GAP score is a novel measure that uses sagittal parameters relative to each patient’s lumbosacral anatomy to predict mechanical complications after ASD surgery. External validation is required.METHODSAdult ASD patients undergoing > 4 levels of posterior fusion with a minimum 2-year follow-up were included. Six-week postoperative standing radiographs were used to calculate the GAP score, classified into a spinopelvic state as proportioned (P), moderately disproportioned (MD), or severely disproportioned (SD). A chi-square analysis, receiver operating characteristic curve, and Cochran-Armitage analysis were performed to assess the relationship between the GAP score and mechanical complications.RESULTSSixty-seven patients with a mean age of 52.5 years (range 18–75 years) and a mean follow-up of 2.04 years were included. Patients with < 2 years of follow-up were included only if they had an early mechanical complication. Twenty of 67 patients (29.8%) had a mechanical complication. The spinopelvic state breakdown was as follows: P group, 21/67 (31.3%); MD group, 23/67 (34.3%); and SD group, 23/67 (34.3%). Mechanical complication rates were not significantly different among all groups: P group, 19.0%; MD group, 30.3%; and SD group, 39.1% (χ2 = 1.70, p = 0.19). The rates of mechanical complications between the MD and SD groups (30.4% and 39.1%) were less than those observed in the original GAP study (MD group 36.4%–57.1% and SD group 72.7%–100%). Within the P group, the rates in this study were higher than in the original study (19.0% vs 4.0%, respectively).CONCLUSIONSThe authors found no statistically significant difference in the rate of mechanical complications between the P, MD, and SD groups. The current validation study revealed poor generalizability toward the authors’ patient population.