bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Determination of Nicotine and Sulfate in Supermarket Ground Beef Adulterated with Black Leaf 40
Authors: Dasenbrock CO , Ciolino LA , Hatfield CL , Jackson DS 
Published: December 2020

Abstract
In December 2002, approximately 250 lbs. of ground beef was adulterated with nicotine sulfate by a supermarket employee and subsequently sold to the public. Soon afterward, reports of illness associated with ground beef purchased at a single store were identified. Authorities suspected the ground beef was tainted with Black Leaf 40, a banned pesticide containing approximately 40% nicotine as nicotine sulfate. Ground beef submitted to our laboratory was analyzed in concert by high performance liquid chromatography-ultraviolet detection (HPLC-UV), gas chromatography-mass spectrometry (GC-MS), and high performance anion exchange chromatography with suppressed conductivity detection. GC-MS was used to identify the samples that contained nicotine. The nicotine was confirmed and quantitated by HPLC-UV. The sulfate was identified and quantitated by high performance anion exchange chromatography with suppressed conductivity detection. Our analysis revealed that the raw tainted beef contained about 350 mg/kg nicotine free base, a potentially lethal dose of nicotine per serving for an adult. Additionally, we found elevated sulfate levels in the samples that tested positive for nicotine, providing evidence that nicotine sulfate was the probable adulterant.
Metabolic Syndrome “Interacts” With COVID-19
Authors: Guo Zeling , Jiang Shanping , Li Zilun , Chen Sifan 
Published: December 2020

Significance statement
Coronavirus disease 2019 (COVID-19) has rapidly spread worldwide and has exerted a great influence on public health and society, urging scientists to find efficient therapeutics. Metabolic disturbance involving various organs has been found in these patients, including diabetes, fatty liver, acute kidney injury (AKI), etc. In turn, these preexisting metabolic syndromes could exacerbate COVID-19. In this review, we focus on the close interaction between COVID-19 and metabolic syndrome, as well as the potential of repurposing metabolic-related drugs and the importance of treating metabolic diseases in COVID-19 patients.

Abstract
COVID-19, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has emerged as a global pandemic and poses a great threat to public health and society in general. SARS-CoV-2 invades cells via its spike protein, which initiates endocytosis via its binding to host receptor angiotensin-converting enzyme 2 (ACE2) and membrane fusion after being cleaved by the serine protease, TMPRSS2. The most common clinical manifestations are fever, dry cough, fatigue and abnormalities on chest computed tomography (CT). However, some patients rapidly progress to severe pneumonia and develop acute respiratory distress syndrome (ARDS). Furthermore, SARS-CoV-2 triggers a severe cytokine storm, which may explain the deterioration of pre-existing metabolic disorders. Interestingly, conversely, underlying metabolic-related diseases, including hypertension, diabetes, cardiovascular disease, etc., are associated with progression and poor prognosis of COVID-19. The putative mechanisms are dysregulation of ACE2, impaired immunity especially uncontrolled hyperinflammation, hypercoagulability, etc. In this review, we summarize the crosstalk between COVID-19 and metabolic diseases and propose that in addition to controlling COVID-19, more intensive attention should be paid to the symptomatic treatment and prevention of pre-existing and foreseeable metabolic comorbidities.
CONOSCERE E CARTOGRAFARE L’IRAN, SPIE E CARTE DI IERI E DI OGGI. PIETRO DELLA VALLE E I VIAGGIATORI EUROPEI NELLA PERSIA DEL PRIMO ‘600 ALLA LUCE DEL PRESENTE
Authors: Mauriello Raffaele 
Published: December 2020

Una delle caratteristiche della prima età moderna è lo sviluppo della cartografia. Fra il 1450 e il 1650 le carte passarono da rappresentare il mondo in modo medievale, in termini di orbis terrae, a una divisione del globo terrestre in segmenti formati da reticolati e coordinate.
Questo cambio fu dovuto in particolare ai numerosi viaggi di esplorazione o avventura e di natura diplomatica intrapresi in quegli anni dagli europei. Anche l’Italia vanta nomi importanti di viaggiatori che contribuirono a questo sviluppo. Nel caso dell’Iran, che all’epoca gli europei chiamavano Persia, il “nostro uomo” è Pietro della Valle (1586-1652). Lui c’era, e con lui lo sguardo e gli interessi dell’Italia, rappresentata all’epoca dallo Stato della Chiesa e dalla Repubblica di Venezia.
Ma della Valle non era solo. Con lui c’erano anche l’inglese Sir Robert Sherley, il tedesco Heinrich von Poser und Groß Naedlitz e lo spagnolo don García de Silva y Figueroa. Essi, ed altri che li seguirono, cercarono di informarsi ed influire sugli affari dell’Iran e della più ampia geopolitica del Vicino Oriente, contribuendo al contempo attraverso i loro resoconti di viaggio ed altri scritti a cartografare il paese.
Mutatis mutandis e in alcuni casi letteralmente sulle tracce dei loro predecessori, oggi come ieri i viaggiatori europei continuano ad interessarsi del paese, e del suo rapporto con l’Europa.
Inteligencia emocional y tutoría docente en prácticantes pre profesionales de una universidad estatal limeña
Authors: Florian Angulo Nilda 
Published: December 2020

La investigación que presentamos, nace desde el interés de mejorar las capacidades relacionadas a las prácticas pre profesionales, las mismas que nos preparan para desenvolvernos como profesionales docentes al termino de los estudios universitarios, hemos observado desde nuestra experiencia universitaria alumnos que muestran inseguridad y vacíos durante el actuar en los mencionados cursos relacionados a las prácticas mencionadas, el estudio se realiza en estudiantes del ultimo año de formación en educación en una universidad pública de Lima. La muestra fue 40% del porcentaje total de estudiantes (122 futuros profesionales del X semestre del curso de práctica pre profesional). La presente investigación tiene por objetivo llegar a conocer e identificar de forma real y objetiva la relación entre tutoría docente con el intelecto emocional en los practicantes pre profesionales que están por egresar. Por las características y función del presente estudio es de corte cuantitativo, descriptivo correlacional de tipo transversal. Usamos el Test REUVEN BAR-ON, para la recolección de datos para la variable X, relacionada con la I.E, así como se utilizó un cuestionario LIKERT para la variable Y relacionada a la tutoría docente.
Según los datos estadísticos del estudio planteado, confirmamos la hipótesis general, determinando una relación significativa entre el acompañamiento docente e inteligencia emocional en los estudiantes de practica pre profesional en cuestión. Se concluye que existen algunas divergencias y carencias en cuanto al aspecto emocional y las habilidades profesionales – pedagógicas, en los practicantes de último ciclo; dado que no expresan respuestas contundentes.
Evaluation of pearl millet (Pennisetum glaucum L. (R. Br.)) landraces for resistance to stem borer (Coniesta ignefusalis Hampson.) infestation
Authors: ABUBAKAR Abdulhakeem , FALUSI Olamide A. , OLAYEMI Israel K. , ADEBOLA Matthew O. , DAUDU Yusuf O. A. , DANGANA Mohammed C. 
Published: December 2020

Characterisation of germplasm collection is imperative for identification and selection of new resistance sources in any crop breeding programmes. Thus, evaluation of pearl millet germplasm for resistance to stem borer infestation was carried out in view of the challenges of poor yield and quality reduction of pearl millet, elicited by its feeding activities. Thirty-five (35) pearl millet accessions were collected from different states where the crop is majorly cultivated in Nigeria. The accessions were characterised for resistance to stem borer infestation on the field. Further confirmation for selected potentially resistant accessions under artificial screen house conditions was done using a randomised complete block design (RCBD) with ten replications each. The field estimated selection index showed that out of the 35 accessions screened, 15 accessions were potentially resistant; 13 resistants with range value of 0.00 to 0.40 and 2 moderately resistant. Further nursery screening confirmed 9 of the 15 accessions to be resistant under artificial infestation. NS-JIL-01 accession was most highly resistant with significant least leaf damage score of 0.25. Significant and positive correlation (r = 0.32) was obtained between days to anthesis and number of larvae per plant at p < 0.01. Negative correlation of percentage internodes damage with panicle diameter (-0.26) and panicle weight (-0.25 gn) at p < 0.01 as well as weight of 1000 seeds (r = -0.19, p < 0.05) were also significant. The identification of potentially resistant accessions on field and confirmation of some of the accessions under artificial screen house conditions indicated, gene for resistance to stem borer infestation in pearl millet could be obtained from the natural eco-type germplasm.
Dysregulated Dynein-Mediated Trafficking of Nephrin Causes INF2-related Podocytopathy
Authors: Sun Hua , Perez-Gill Chandra , Schlöndorff Johannes S , Subramanian Balajikarthick , Pollak Martin R. 
Published: December 2020

Background
FSGS caused by mutations in INF2 is characterized by a podocytopathy with mistrafficked nephrin, an essential component of the slit diaphragm. Because INF2 is a formin-type actin nucleator, research has focused on its actin-regulating function, providing an important but incomplete insight into how these mutations lead to podocytopathy. A yeast two-hybridization screen identified the interaction between INF2 and the dynein transport complex, suggesting a newly recognized role of INF2 in regulating dynein-mediated vesicular trafficking in podocytes.

Methods
Live cell and quantitative imaging, fluorescent and surface biotinylation-based trafficking assays in cultured podocytes, and a new puromycin aminoglycoside nephropathy model of INF2 transgenic mice were used to demonstrate altered dynein-mediated trafficking of nephrin in INF2 associated podocytopathy.

Results
Pathogenic INF2 mutations disrupt an interaction of INF2 with dynein light chain 1, a key dynein component. The best-studied mutation, R218Q, diverts dynein-mediated postendocytic sorting of nephrin from recycling endosomes to lysosomes for degradation. Antagonizing dynein-mediated transport can rescue this effect. Augmented dynein-mediated trafficking and degradation of nephrin underlies puromycin aminoglycoside-induced podocytopathy and FSGS in vivo.

Conclusions

INF2 mutations enhance dynein-mediated trafficking of nephrin to proteolytic pathways, diminishing its recycling required for maintaining slit diaphragm integrity. The recognition that dysregulated dynein-mediated transport of nephrin in R218Q knockin podocytes opens an avenue for developing targeted therapy for INF2-mediated FSGS.
MAKING SILL TABLE WITH THE MATERIAL OF WOOD WASTE AND RESIN
Authors: Naim Sultono Bin , Irwanto Asep Ahmad Ruri 
Published: December 2020

ABSTRACT – The activity of workshop practicum construction materials-based, Construction Engineering of Civil Engineering Education Department’s Workshop, produces wastes such as woods pieces, sawdust, galvanized pipe pieces/PVC that are still not able to utilized maximally. Every semester, yield of the practicum activity becomes waste. The research making table from wood waste and resin is one of solution and innovation to utilize the waste to become having more economic values. In the previous study, with physical and mechanical test, it could be found that the tighter the assembly of wood waste, the stronger its capability to hold its tensile force.This research used qualitative method. From the supervising of the steps of making sill table from the material of wood waste and resin, there is one type of sill table which was implemented in this research, it is split the wood waste into elongated. This research was done by three times trials with different kinds formula of resin and catalyst.The result of this research is the steps and formula of the volume comparison of resin and catalyst to make sill table from waste and resin that could be a learning guidance for woods construction practice subject and interior finishing practice subject in Construction Engineering Education Study Program and giving solution as a form of responsibility for waste handling. Keywords: Wood waste, Table, Resin.
ENHANCING COMMUNITY ENVIRONMENTAL AWARENESS THROUGH INDOOR AIR QUALITY WORKSHOP
Authors: Kencanasari R.A Vesitara , Surahman Usep , Permana Asep Yudi , Nugraha Hari Din 
Published: December 2020

Abstract - This research is motivated by the poor air quality in the room at home that can cause Sick Building Syndrome (SBS). The purpose of this research is to increase public awareness of the environment through indoor air quality workshops, with a Pre-Experimental method and One Group Pre-Test Post-Test research design. The sample in this study was Pasteur RW6, Sukajadi District at Bandung City, which was selected based on criteria including non slum areas, as well as high community participation. The results showed that the level of public awareness, knowledge, attitudes, and actions on air quality in the room before the Workshop was in the medium category. Then it increased after the Workshop, which was on a relatively moderate increase in knowledge. This can be seen from the majority of people who already know the importance of indoor air quality, but the knowledge of specific components that affect indoor air quality is still not understood. Whereas attitudes and actions experienced a relatively small increase due to the knowledge gained in the Workshop not being implemented in the form of real attitudes and actions in daily life because people's habits are difficult to change. Keywords – Environmental Awareness, Indoor Air Quality, Workshop, Community Awareness
The failure by the court to take measures to return the criminal case to the prosecutor in accordance with art. 237 of the code of criminal procedure of the Russian federation as an unconditional basis for canceling the sentence
Authors: Perova E. A. 
Published: December 2020

Part 2 of Article 389.17 of the Criminal Procedure Code of the Russian Federation establishes a list of unconditionally significant violations of the norms of the criminal procedure law, the identification of which in a case entails the cancellation or change of the sentence in every case without exception. The range of these violations was determined by the legislator during the development of the Code of Criminal Procedure of the Russian Federation in 2001, and has not changed since then. However, the rules, violation of which can affect the quality of the sentence and lead to its cancellation in each case, have changed more than once. Including the norms governing the institution of returning the case to the prosecutor in accordance with Art. 237 of the Code of Criminal Procedure of the Russian Federation and determining the significance of this institution for the issuance of a legal, reasonable and fair sentence. In this regard, this article discusses the feasibility of expanding the list of unconditional grounds for canceling a sentence by including a violation associated with the failure of the court to take measures to return the criminal case to the prosecutor in accordance with Art. 237 of the Criminal Procedure Code of the Russian Federation, if there are grounds for that.
Rupture Process of theM6.5 Stanley, Idaho, Earthquake Inferred from Seismic Waveform and Geodetic Data
Authors: Pollitz Fred F. , Hammond William C. , Wicks Charles W. 
Published: December 2020

AbstractThe 2020 M 6.5 Stanley, Idaho, earthquake produced rupture in the north of the active Sawtooth fault in the northern basin and range at depth, without any observable surface rupture. Global Positioning System (GPS) and Interferometric Synthetic Aperture Radar (InSAR) data yield several millimeters of static offsets out to ∼100  km from the rupture and up to ∼0.1  m of near-field crustal deformation. We combine the GPS and InSAR data with long-period regional seismic waveforms to derive models of kinematic slip and afterslip. We find that the coseismic rupture is complex, likely involving up to 2 m combined left-lateral strike slip and normal slip on a previously unidentified ∼south-southeast-striking fault. This slip is predominantly left-lateral strike slip, different from the dominant east-northeast–west-northwest normal faulting of the region. At least one ∼northeast-trending fault, likely associated with the Trans-Challis fault system, is inferred to have accommodated a few decimeters of right-lateral afterslip, consistent with vigorous aftershock activity at depth along northeast-trending lineations.
Root Causes and Consequences of Extreme Poverty in Northern Bangladesh
Authors: Barman Ram Proshad , Islam Mousume 
Published: December 2020

Poverty has always become major concern due to multifarious reasons in the Northern part of Bangladesh from the very earlier years of independent Bengal. The concoction of this study is to find out the root causes and consequence of extreme poverty in Northern Bangladesh. Following purposive sampling a survey is conducted at 8 villages of Kurigram district from October December 2019. In addition, the researcher distributed a total of 106 surveys to respondents for analyzing and interpreting target population. The study revealed that the most vulnerable groups in the selected area were agricultural wage laborer’s, landless and marginal farmers, children, women and aged people while food shortages, livelihood patterns, lack of industry, extreme unemployment and overall dependency associated with poverty scales and such states create more penetration on these community. The study concluded that hazardous events, Monga situation, resource scarcity, poor socio-economic structure and underdeveloped infrastructure solely deployed extreme poverty in the study region. Lastly, it is also designed to suggest how to reduce the extreme poverty following various poverty reduction programs by NGOs and government of Bangladesh using measurement scales towards standard livelihood in northern region.
THE ROLE AND SIGNIFICANCE OF THE SHORT-TERM RESULT AND PRAXEOLOGICAL ANALYSIS OF THE COMPANY’S OPERATIONAL ACTIVITY (ON THE EXAMPLE OF PRZEDSIĘBIORSTWO GOSPODARKI KOMUNALNEJ W ŚREMIE SPÓŁKA Z O. O.)
Authors: Вартецький Анджей , Єрмач Веслав Жозеф 
Published: December 2020

The essence of the research is the cognitive and decision-making values of the result analysis and praxeological operational activity of the enterprise in a short period of time. The aim of the research is to indicate the role and importance of the above-mentioned decision-making instruments in the context of the dynamics of economic activity and quick feedback from the market.
The subject of the considerations presented in the article is to present the role and importance of a short-term analysis of the resulting operational and praxeological activity of an enterprise (on the example of Przedsiębiorstwo Gospodarki Komunalnej w Śremie Spółka z o. o.).
The essence of the considerations is contained in the specific solutions presented in the article in the field of controlling and indications of possible corrective and remedial actions, etc., e.g. the financial situation of the examined enterprise. Based on the results of the research, it can be concluded that the short-term financial analysis plays an important role in assessing the functioning of this type of companies. It is also an important instrument for optimizing activities and processes within the package of instruments, including those in the field of management engineering.
Saberes locais e autoria nas práticas de leitura e escrita: uma análise comparativa
Authors: De Oliveira Ribeiro Mariana Aparecida , Apoliano da Silva Raina Kathleem 
Published: December 2020

Este artigo teve por objetivo analisar as aulas de língua materna e os textos produzidos em contextos rurais e/ou multiculturais no Brasil e no Peru (Bacabal e Tumbes, respectivamente). Tivemos por objeto de pesquisa a relação entre saberes locais e autoria. Focamos analisar quais são e como os saberes locais são incorporados nas aulas de leitura e escrita nos dois países que fizeram parte desta investigação. Partimos da seguinte pergunta de pesquisa: em que medida a singularidade dos contextos locais onde estão inseridos os migrantes, imigrantes, quilombolas, integrantes de comunidades rurais e assemelhados é contemplada na aula de língua materna na qual se espera que esses participantes aprendam a ler e a escrever?. Realizamos uma pesquisa etnográfica com metodologia qualitativa, que se insere no projeto de estágio internacional Práticas escolares em contextos rurais e/ou multiculturais: um estudo sobre a leitura e escrita no Brasil e Peru financiado pela FAPEMA (Edital 037/2017) e resulta de uma pesquisa de Iniciação Científica (cota 2018-2019/FAPEMA). Fundamentamo-nos teoricamente em Barzotto (2016), Calil (2004), Possenti (2009) e Foucault (1970 [2000]). Os resultados apontaram que os saberes locais não foram inseridos no texto como argumento para modificar a direção argumentativa do texto e nem como um argumento inovador.
Autismo e inclusão escolar: em busca de diálogos interdisciplinares com a dança.
Authors: Pereira Andrade Douglas Louzakan , Otavio Murad Carla Regina Rachid 
Published: December 2020

O objetivo deste trabalho foi, a partir de uma revisão bibliográfica de estudos em dança e autismo, verificar o tipo de conhecimento que as práticas científicas de pesquisa nestes campos de conhecimento têm promovido no contexto escolar. O referencial teórico se pautou na noção de Michel Foucault (2004) de práticas discursivas que se constituem pela ordem do discurso poder-saber e que vai deixando marcas enunciativas constitutivas dos sujeitos através de práticas institucionais de produção escrita acadêmicas. Foram analisados quatro trabalhos de pesquisa escritos em língua portuguesa acessados e selecionados por meio das bases nacionais e internacionais publicadas nos últimos cinco anos. Os dados foram organizados e analisados em três frentes de indagação: interdisciplinaridade ou disciplinarização; educação e inclusão e sujeito e objetivo de pesquisa. Os resultados sugerem que as concepções de dança dos trabalhos provocam distorções nos desenhos metodológicos que, por sua vez, recortam os sujeitos em grupos-objetos segregados de controle. Concluímos que a escola, enquanto instituição, tem incorporado conhecimentos de diversos campos do saber com o objetivo precípuo de manter o controle destes sujeitos.
ПРОПАГАНДНА ПОЕТИКА КЛАУДИЈА КЛАУДИЈАНА ИЛИ НАМЕТНУТА КУЛТУРА СЕЋАЊА
Authors: Вукадиновић Снежана 
Published: December 2020

Аутор рада тумачи појам пропаганде са посебним освртом на поетику Клаудија Клаудијана, песника позне римске књижевности. У фокусу је његов први панегирик на латинском језику који се јавно читао у част двојице конзула, али браће, што до тада није био обичај.