bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strength training restores force‐generating capacity in patients with schizophrenia
Authors: Nygård Mona , Brobakken Mathias Forsberg , Taylor Joshua Landen , Reitan Solveig Klæbo , Güzey Ismail Cüneyt , Morken Gunnar , Lydersen Stian , Vedul‐Kjelsås Einar , Wang Eivind , Heggelund Jørn 
Published: October 2020

Patients with schizophrenia spectrum disorders have impaired skeletal muscle force‐generating capacity (FGC) of the lower extremities, that is, one repetition maximum (1RM) and rapid force development, and poor functional performance. We therefore investigated whether 12 weeks of maximal strength training (MST) could (a) restore FGC and functional performance to the level of healthy references, (b) increase patient activation and quality of life, and (c) explore associations between symptom severity, defined daily dose of medication, illness duration, level of patient activation, and improvements in FGC and functional performance. Forty‐eight outpatients were randomized to a training group (TG) or control group (CG). TG performed leg press MST 2 day/week at ~ 90% 1RM. The CG received two introductory training sessions and encouragement to train independently. Leg press 1RM, rapid force development, a battery of functional performance tests, Patient Activation Measure‐13, and 36‐Item Short Form Health Survey were tested. Healthy references performed baseline tests of FGC and functional performance. Thirty‐six patients completed the study (TG: 17, CG: 19). TG improved 1RM (28%) and rapid force development (20%, both P < .01) to a level similar to healthy references, while no change was apparent in the CG. TG’s improvement in rapid force development was negatively associated with defined daily dose of medication (r = −0.5, P = .05). Both TG and CG improved 30‐second sit‐to‐stand test performance (P < .05) which was associated with improved rapid force development (r = 0.6, P < .05). In conclusion, 12 weeks of MST restored patients’ lower extremity FGC to a level similar to healthy references and improved 30‐second sit‐to‐stand test performance.
Effects of including sprints during prolonged cycling on hormonal and muscular responses and recovery in elite cyclists
Authors: Almquist Nicki Winfield , Ellefsen Stian , Sandbakk Øyvind , Rønnestad Bent R. 
Published: October 2020

This study investigated the acute effects of including 30‐second sprints during prolonged low‐intensity cycling on muscular and hormonal responses and recovery in elite cyclists. Twelve male cyclists (VO2max, 73.4 ± 4.0 mL/kg/min) completed a randomized crossover protocol, wherein 4 hours of cycling at 50% of VO2max were performed with and without inclusion of three sets of 3 × 30 seconds maximal sprints (E&S vs E, work‐matched). Muscle biopsies (m. vastus lateralis) and blood were sampled at Pre, immediately after (Post) and 3 hours after (3 h) finalizing sessions. E&S led to greater increases in mRNA levels compared with E for markers of fat metabolism (PDK4, Δ‐Log2 fold change between E&S and E ± 95%CI Post; 2.1 ± 0.9, Δ3h; 1.3 ± 0.7) and angiogenesis (VEGFA, Δ3h; 0.3 ± 0.3), and greater changes in markers of muscle protein turnover (myostatin, ΔPost; −1.4 ± 1.2, Δ3h; −1.3 ± 1.3; MuRF1, ΔPost; 1.5 ± 1.2, all P < .05). E&S showed decreased mRNA levels for markers of ion transport at 3h (Na+‐K+ α1; −0.6 ± 0.6, CLC1; −1.0 ± 0.8 and NHE1; −0.3 ± 0.2, all P < .05) and blunted responses for a marker of mitochondrial biogenesis (PGC‐1α, Post; −0.3 ± 0.3, 3h; −0.4 ± 0.3, P < .05) compared with E E&S and E showed similar endocrine responses, with exceptions of GH and SHBG, where E&S displayed lower responses at Post (GH; −4.1 ± 3.2 μg/L, SHBG; −2.2 ± 1.9 nmol/L, P < .05). Both E&S and E demonstrated complete recovery in isokinetic knee extension torque 24 hours after exercise. In conclusion, we demonstrate E&S to be an effective exercise protocol for elite cyclists, which potentially leads to beneficial adaptations in skeletal muscle without impairing muscle recovery 24 hours after exercise.
Is “Latino” useful? Diversity, commonality, and politics
Authors: Licea Ricardo 
Published: October 2020

AbstractThe Latino classification is distinct from all other racial or ethnic classifications employed in the United States as it is not based on shared physical appearance or geographical origin, instead Latinos are those who hail from a portion of the territories that once belonged to the Spanish Empire regardless of their ancestry or physical appearance. The diversity within the Latino classification means that it is unclear what is being measured when the Latino classification is used to conduct science. Regardless of the Latino classification's usefulness for science the Latino classification has been defended for its usefulness in helping redress the consequences of racism against Latinos. However, the ultimate cause of this discrimination is that most Latinos have a non‐White appearance making the Latino classification a poor proxy for any effort to address racism. The solution is not to return to the classification system that existed prior to the creation of the Latino classification but to instead adopt more granular classifications employed in Latin America such as Mestizo and Mulatto. This will allow for a more detailed study of discrimination and the redirection of resources to those most in need.
Co‐occurrence of and risk factors for Cryptosporidium and Giardia in brown rats from Buenos Aires, Argentina
Authors: Hancke Diego , Suárez Olga Virginia 
Published: October 2020

AbstractA rodent survey was conducted in different landscape units of the city of Buenos Aires (Argentina) to determine the prevalence of Cryptosporidium and Giardia in Rattus norvegicus and to, ultimately, assess the biotic, environmental and meteorological factors that explain the variations of the likelihood of infection for both parasites in an urban environment. The results of this study revealed a ubiquitous presence of Cryptosporidium and Giardia in R. norvegicus within an urban environment with the likelihood of infection depending on environmental and meteorological conditions for both parasites. The overall prevalence was greater for Cryptosporidium (p = 50.4%) than for Giardia (20.3%). The prevalence for both parasites separately was higher in parks compared to shantytowns and scrap metal yards. Generalized Linear Mixed Models revealed that the occurrence of these parasites separately, at an individual level, was positively related with rainfall variables and that the effect of temperature depended on the landscape unit. The similarities in the transmission modes, which are affected by common extrinsic factors, may facilitate the co‐occurrence of Cryptosporidium and Giardia in urban rats. Rattus norvegicus is recognized as a good model for epidemiological studies and the results of this work suggest that, from an epidemiological point of view, the probability of contact with infectious oocysts and cysts of these parasites can be modulated through environmental management and healthy behaviour towards risk factors. The information presented here will be useful to improve the understanding of the dynamics of zoonotic diseases within urban environments and to contribute to the decision‐making of new and effective prophylactic measures.
Application of Transient Electromagnetic Method in Municipal Buried Gas Pipeline Detection
Authors: Song Pan , Pu Zhe , Ren Bin , Tang Xiaoying , Wang Jielu 
Published: October 2020

Abstract
The safe operation of gas pipeline is related to the liveihood of people, in the process of operation, many factors will cause pipeline failure, leakage and accidents and thus impair people’s well-being and property safety. This paper puts forward the transient electromagnetic method for in-service detection of municipal buried gas pipeline, mainly introduces the principle of transient electromagnetic method and the factor analysis of pipeline failure, and comprehensively analyzes the problems existing in the application of transient electromagnetic method in in-service detection of municipal buried gas pipeline combined with two examples of gas pipeline detection. The result shows that transient electromagnetic method is practical in the detection of municipal buried gas pipeline, which can better distinguish corrosion thinning and interference, and provide reliable theoretical data basis for in-service safe operation detection and maintenance of municipal buried gas pipeline.
Outcomes of Three Large Scale Fire Reference Tests Conducted in BAM Fire Test Facility
Authors: Feldkamp Martin , Quercetti Thomas , Wille Frank 
Published: October 2020

Abstract
Packages for the transport of high-level radioactive material are designed to withstand severe accidents. Hypothetical severe accident conditions are defined in the IAEA Regulations for the Safe Transport of Radioactive Materials. One of these accident conditions is the thermal test, mainly consisting of a 30 minute fully engulfing 800°C pool fire or an equally severe fire test. The heat fluxes into the package depend substantially on the fire characteristics and the surface temperature of the package.
Fire tests can be performed at BAM on a propane gas fire test facility. In order to investigate the heat fluxes over a wide range of surface temperatures in this test facility a fire reference package was designed for multiple use. The package represented the outer geometry of a specific transport cask for radioactive waste. The fire reference package is a closed steel sheet cylinder with a wall thickness of 10 mm, a length of 1500 mm and a diameter of 1050 mm. The package was instrumented with thermocouples and filled with heat resistant insulation material. Three open-air fire tests were performed in the BAM propane gas fire test facility. The flames exposure time period varied slightly for the fire tests. The wind direction as well as the wind speed were measured and changed between and during the tests. Test stand parameters such as wind shield location and propane gas volume flow were chosen constant for the three tests. The locally measured fire reference package steel sheet temperatures were used for the calculation of heat fluxes as function of time and surface temperature. The measured temperatures allowed further calculations. In a first approach effective fire characteristics of the propane gas fire, including the flame temperature, the fire convection coefficient and a radiation exchange coefficient mathematically describing the determined average heat flux over the surface temperature were calculated.
Measuring Fatigue Crack Growth Behavior of Ferritic Steels Near Threshold in High Pressure Hydrogen Gas
Authors: Ronevich Joseph , San Marchi Chris , Nibur Kevin A. , Bortot Paolo , Bassanini Gianluca , Sileo Michele 
Published: October 2020

Abstract
Following the ASME codes, the design of pipelines and pressure vessels for transportation or storage of high-pressure hydrogen gas requires measurements of fatigue crack growth rates at design pressure. However, performing tests in high pressure hydrogen gas can be very costly as only a few laboratories have the unique capabilities. Recently, Code Case 2938 was accepted in ASME Boiler and Pressure Vessel Code (BPVC) VIII-3 allowing for design curves to be used in lieu of performing fatigue crack growth rate (da/dN vs. ΔK) and fracture threshold (KIH) testing in hydrogen gas. The design curves were based on data generated at 100 MPa H2 on SA-372 and SA-723 grade steels; however, the data used to generate the design curves are limited to measurements of ΔK values greater than 6 MPa m1/2. The design curves can be extrapolated to lower ΔK (&lt; 6 MPa m1/2), but the threshold stress intensity factor (ΔKth) has not been measured in hydrogen gas. In this work, decreasing ΔK tests were performed at select hydrogen pressures to explore threshold (ΔKth) for ferritic-based structural steels (e.g. pipelines and pressure vessels). The results were compared to decreasing ΔK tests in air, showing that the fatigue crack growth rates in hydrogen gas appear to yield similar or even slightly lower da/dN values compared to the curves in air at low ΔK values when tests were performed at stress ratios of 0.5 and 0.7. Correction for crack closure was implemented, which resulted in better agreement with the design curves and provide an upper bound throughout the entire ΔK range, even as the crack growth rates approach ΔKth. This work gives further evidence of the utility of the design curves described in Code Case 2938 of the ASME BPVC VIII-3 for construction of high pressure hydrogen vessels.
Study on Multifunctional Base Isolation System Using Air-Floating Technique
Authors: Furuya Osamu , Takito Kiyotaka , Kurabayashi Hiroshi , Sampei Kunio , Yamazaki Koji 
Published: October 2020

Abstract
Vibration isolation devices are generally applied to equipment that dislikes vibration installed in buildings. Since the vibration isolator is intended for small vibration input, the damage has been frequently confirmed with excessive vibration input such as an huge earthquake motion. Therefore, the development of a seismic isolation device with a vibration isolation function is desired for important equipment and expensive manufacturing equipment.
However, the vibration region targeted by the vibration isolator and the vibration region of the seismic input are at completely different levels. In this study, the authors propose a seismic isolation system using air floating technique to cope with such different vibration levels. In this paper, basic concept, basic performance, preliminary performance evaluation by nonlinear time response analysis, and performance evaluation by shaking table test.
Assessing the efficiency of countries in making progress towards universal health coverage: a data envelopment analysis of 172 countries
Authors: Jordi Emma , Pley Caitlin , Jowett Matthew , Abou Jaoude Gerard Joseph , Haghparast-Bidgoli Hassan 
Published: October 2020

IntroductionMaximising efficiency of resources is critical to progressing towards universal health coverage (UHC) and the sustainable development goal (SDG) for health. This study estimates the technical efficiency of national health spending in progressing towards UHC, and the environmental factors associated with efficient UHC service provision.MethodsA two-stage efficiency analysis using Simar and Wilson’s double bootstrap data envelopment analysis investigates how efficiently countries convert health spending into UHC outputs (measured by service coverage and financial risk protection) for 172 countries. We use World Bank and WHO data from 2015. Thereafter, the environmental factors associated with efficient progress towards UHC goals are identified.ResultsThe mean bias-corrected technical efficiency score across 172 countries is 85.7% (68.9% for low-income and 95.5% for high-income countries). High-achieving middle-income and low-income countries such as El Salvador, Colombia, Rwanda and Malawi demonstrate that peer-relative efficiency can be attained at all incomes. Governance capacity, income and education are significantly associated with efficiency. Sensitivity analysis suggests that results are robust to changes.ConclusionWe provide a 2015 baseline for cross-country UHC technical efficiency scores. If countries wish to improve their UHC outputs within existing budgets, they should identify their current efficiency and try to emulate more efficient peers. Policy-makers should focus on strengthening institutions and implementing known best practices to replicate efficient systems. Using resources more efficiently is likely to positively impact UHC coverage goals and health outcomes, and without addressing gaps in efficiency progress towards achieving the SDGs will be impeded.
In pursuit of ‘safe’ water: the burden of personal injury from water fetching in 21 low-income and middle-income countries
Authors: Venkataramanan Vidya , Geere Jo-Anne L , Thomae Benjamin , Stoler Justin , Hunter Paul R , Young Sera L 
Published: October 2020

IntroductionWater fetching for household needs can cause injury, but documentation of the burden of harm globally has been limited. We described the frequency, characteristics and correlates of water-fetching injuries in 24 sites in 21 low-income and middle-income countries in Asia, Africa and Latin America and the Caribbean.MethodsIn a survey of 6291 randomly selected households, respondents reported whether and how they had experienced water-fetching injuries. Responses were coded for injury type, mechanism, bodily location and physical context. We then identified correlates of injury using a multilevel, mixed-effects logistic regression model.ResultsThirteen per cent of respondents reported at least one water-fetching injury. Of 879 injuries, fractures and dislocations were the most commonly specified type (29.2%), and falls were the most commonly specified mechanism (76.4%). Where specified, 61.1% of injuries occurred to the lower limbs, and dangerous terrain (69.4%) was the most frequently reported context. Significant correlates included being female (aOR=1.50, 95% CI 1.15 to 1.96); rural (aOR=4.80, 95% CI 2.83 to 8.15) or periurban residence (aOR=2.75, 95% CI 1.64 to 4.60); higher household water insecurity scores (aOR=1.09, 95% CI 1.07 to 1.10) and reliance on surface water (aOR=1.97, 95% CI 1.21 to 3.22) or off-premise water sources that required queueing (aOR=1.72, 95% CI 1.19 to 2.49).ConclusionThese data suggest that water-fetching injuries are an underappreciated and largely unmeasured public health challenge. We offer guidelines for comprehensive data collection on injuries to better capture the true burden of inadequate water access. Such data can guide the design of interventions to reduce injury risk and promote equitable water access solutions.
“I’m in a very good frame of mind”: a qualitative exploration of the experience of standing frame use in people with progressive multiple sclerosis
Authors: Dennett Rachel , Hendrie Wendy , Jarrett Louise , Creanor Siobhan , Barton Andrew , Hawton Annie , Freeman Jennifer A 
Published: October 2020

ObjectivesThe study aim was to explore the experiences of people with progressive multiple sclerosis (MS) and their standing assistants during their participation in Standing Up in Multiple Sclerosis, a randomised controlled trial (RCT) of a home-based, self-managed standing frame programme.DesignA qualitative approach, using audio diary methodology was used to collect data contemporaneously. Diary data were transcribed verbatim and analysed using thematic analysis.SettingParticipants were recruited from eight healthcare organisations in two regions of the UK. The intervention was home-based.ParticipantsAs part of the RCT, 140 participants were randomly allocated to either usual care or usual care plus a standing frame programme. Using a sampling matrix 12 people with progressive MS (6 female, aged 35–71 years, Expanded Disability Status Scale 6.5–8.0) and 8 standing assistants (4 female) kept audio diaries of their experiences.InterventionThe standing frame programme involved two face-to-face home-based physiotherapy sessions to set up the standing frame programme, supplemented by educational material designed to optimise self-efficacy. Participants were encouraged to stand for at least 30 min, three times a week for the 36-week study period.ResultsFour main themes were identified: “Feeling like the old me”; ‘Noticing a difference’; “I want to do it right” and “You have a good day, you have a bad day”.ConclusionsSupported standing helped people with progressive MS feel more like their old selves and provided a sense of normality and enjoyment. People noticed improvements in physical and psychological symptoms, which were often associated with increased participation in activities they valued. Provision of support from a physiotherapist and recognition of the variable nature of the condition were highlighted as factors to consider when establishing a standing programme.Trial registration numberISRCTN69614598.
Effects of bright light therapy for depression during pregnancy: a randomised, double-blind controlled trial
Authors: Bais Babette , Kamperman Astrid M , Bijma Hilmar H , Hoogendijk Witte JG , Souman Jan L , Knijff Esther , Lambregtse-van den Berg Mijke P 
Published: October 2020

ObjectivesApproximately 11%–13% of pregnant women suffer from depression. Bright light therapy (BLT) is a promising treatment, combining direct availability, sufficient efficacy, low costs and high safety for both mother and child. Here, we examined the effects of BLT on depression during pregnancy.DesignRandomised, double-blind controlled trial.SettingPrimary and secondary care in The Netherlands, from November 2016 to March 2019.Participants67 pregnant women (12–32 weeks gestational age) with a DSM-5 diagnosis of depressive disorder (Diagnostic and Statistical Manual of Mental Disorders).InterventionsParticipants were randomly allocated to treatment with either BLT (9000 lux, 5000 K) or dim red light therapy (DRLT, 100 lux, 2700 K), which is considered placebo. For 6 weeks, both groups were treated daily at home for 30 min on awakening. Follow-up took place weekly during the intervention, after 6 weeks of therapy, 3 and 10 weeks after treatment and 2 months postpartum.Primary and secondary outcome measuresDepressive symptoms were measured primarily with the Structured Interview Guide for the Hamilton Depression Scale—Seasonal Affective Disorder. Secondary measures were the Hamilton Rating Scale for Depression and the Edinburgh Postnatal Depression Scale. Changes in rating scale scores of these questionnaires over time were analysed using generalised linear mixed models.ResultsMedian depression scores decreased by 40.6%–53.1% in the BLT group and by 50.9%–66.7% in the DRLT group. We found no statistically significant difference in symptom change scores between BLT and DRLT. Sensitivity and post-hoc analyses did not change our findings.ConclusionsDepressive symptoms of pregnant women with depression improved in both treatment arms. More research is necessary to determine whether these responses represent true treatment effects, non-specific treatment responses, placebo effects or a combination hereof.Trial registration numberNTR5476.
Predictive validity of PRISMA-7 as a screening instrument for frailty in a hospital setting
Authors: Hoffmann Sarah , Wiben Amalie , Kruse Marie , Jacobsen Katja Kemp , Lembeck Maurice A , Holm Ellen Astrid 
Published: October 2020

ObjectivesFrailty is a major clinical geriatric syndrome associated with serious adverse events including functional disability, falls, hospitalisation, increased morbidity and mortality. The aim of this study was to study the associations between frailty defined as Program of Research to Integrate Services for the Maintenance of Autonomy (PRISMA-7) score ≥3 and use of healthcare resources in hospital and in the municipality as well as association between frailty and mortality.DesignRegister-based retrospective study.SettingThe target population consists of patients aged 75 years or above who, during hospital stay, were assessed by a physiotherapist, and at discharge from hospital were prescribed further physical training in the community.Participants973 individuals aged 75+ years were included.Outcome measuresWe examined associations between frailty and use of healthcare resources in hospital and in the municipality as well as the association between frailty and mortality.Results973 individuals aged 75+ years were included. Of these, 63.9% had a PRISMA-7 score ≥3 and were thus defined as frail. Frail individuals were older compared with non-frail with mean ages of 84.6 and 80.4 years, respectively, p>0.001. Age and gender-adjusted mortality after 1 year was higher among the frail (OR 2.46, 95% CI 1.53 to 3.97). Use of healthcare services in the municipality as well as hospital admissions was significantly higher among frail individuals.ConclusionsBased on these findings we consider PRISMA-7 to be useful in an in-hospital setting as a screening tool to identify frail elderly patients who may profit from further geriatric assessment during hospital stay.Trial registration numberID REG-070-2017.