bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desempeño de la cognición social en niños y niñas inmersos en la dinámica del acoso escolar en la ciudad de Neiva, Colombia
Authors: Bonilla Santos Jasmin , Bonilla- Santos Gisella , Gutiérrez Sterling Daniela , Gomez - Morales Duván Fernando , Gonzalez-Hernandez Alfredis 
Published: March 2020

La presente investigación tuvo como objetivo comparar el desempeño en ejecución de las pruebas de cognición social en los perfiles de niños y niñas vinculados al acoso escolar en una institución educativa pública de la ciudad de Neiva. Con un diseño de tipo transversal y a través de un muestreo no probabilístico de tipo intencional, se evaluaron 103 estudiantes de básica primaria seleccionados de acuerdo con los criterios de elegibilidad. Los resultados mostraron una mayor frecuencia de niños que se identificaron como observadores-víctimas y un desempeño inferior en las pruebas de faux pas-metida de pata, historias extrañas de Happé y test de miradas en la comparación por perfiles de acoso escolar y la edad. Los resultados sugieren profundizar en estudios que relacionen la convivencia escolar con el desarrollo de la cognición social que relacionen las características sociodemográficas en las poblaciones estudiadas.
Precipitation phase uncertainty in cold region conceptual models resulting from meteorological forcing time-step intervals
Authors: Feiccabrino James M. 
Published: March 2020

Abstract
Precipitation phase determination is a known source of uncertainty in surface-based hydrological, ecological, safety, and climate models. This is primarily due to the surface precipitation phase being a result of cloud and atmospheric properties not measured at surface meteorological or hydrological stations. Adding to the uncertainty, many conceptual hydrological models use a 24-h average air temperature to determine the precipitation phase. However, meteorological changes to atmospheric properties that control the precipitation phase often substantially change at sub-daily timescales. Model uncertainty (precipitation phase error) using air temperature (AT), dew-point temperature (DP), and wet-bulb temperature (WB) thresholds were compared using averaged and time of observation readings at 1-, 3-, 6-, 12-, and 24-h periods. Precipitation phase uncertainty grew 35–65% from the use of 1–24 h data. Within a sub-dataset of observations occurring between AT −6 and 6 °C representing 57% of annual precipitation, misclassified precipitation was 7.9% 1 h and 11.8% 24 h. Of note, there was also little difference between 1 and 3 h uncertainty, typical time steps for surface meteorological observations.
Experimental study of a novel solar multi-effect distillation unit using alternate storage tanks
Authors: Alsehli M. , Saleh B. , Elfasakhany A. , Aly Ayman A. , Bassuoni M. M. 
Published: March 2020

Abstract
In recent years, the use of solar energy has been growing exponentially and applied in a wider range of applications; one of the important applications for using solar energy is water desalination. The current work investigates the proof of concept experimental setup for a novel solar multi-effect distillation (MED) using alternate storage tanks. The experimental setup consists of a MED unit, two thermal storage tanks, and a solar collector. One storage tank is used as a charging tank while the other tank is used as a discharging tank. This unique dual-tank system stores the thermal energy to be used later in the MED unit, which improves the control of the water mass flow rate and water temperature throughout the MED process. The peak temperature achieved every day in the charging tank determines the MED production capacity. This system is designed for the tanks to alternate roles every 24 hours. The testing of this design was carried out during May 2019 in Saudi Arabia. The experimental results prove the novel concept design to work efficiently providing an average production rate of about 21 kg/day with total solar collector area of 2.7 m2 and average daily performance ratio of 2.5.
MVSC: A Multi-variation Simulator of Cancer Genome
Authors: Li Ning , Yang Jialiang , Zhu Wen , Liang Ying 
Published: March 2020

Background:
Many forms of variations exist in the genome, which are the main causes
of individual phenotypic differences. The detection of variants, especially those located in the
tumor genome, still faces many challenges due to the complexity of the genome structure. Thus,
the performance assessment of variation detection tools using next-generation sequencing
platforms is urgently needed.

Method:
We have created a software package called the Multi-Variation Simulator of Cancer
genomes (MVSC) to simulate common genomic variants, including single nucleotide
polymorphisms, small insertion and deletion polymorphisms, and structural variations (SVs), which
are analogous to human somatically acquired variations. Three sets of variations embedded in
genomic sequences in different periods were dynamically and sequentially simulated one by one.

Results:
In cancer genome simulation, complex SVs are important because this type of variation is
characteristic of the tumor genome structure. Overlapping variations of different sizes can also
coexist in the same genome regions, adding to the complexity of cancer genome architecture. Our
results show that MVSC can efficiently simulate a variety of genomic variants that cannot be
simulated by existing software packages.

Conclusion:
The MVSC-simulated variants can be used to assess the performance of existing tools
designed to detect SVs in next-generation sequencing data, and we also find that MVSC is memory
and time-efficient compared with similar software packages.
Production of Recombinant HIV-1 p24-Nef Protein in Two Forms as Potential Candidate Vaccines in Three Vehicles
Authors: Larijani Mona Sadat , Pouriayevali Mohammad Hassan , Sadat Seyed Mehdi , Ramezani Amitis 
Published: March 2020

Background:
Different approaches have been investigated to develop a preventive or therapeutic
vaccine, although none of them has been fully practical. Therapeutic vaccines against HIV-1
have been studied with the aim of eliminating the virus from reservoir cells with or without HAART
(Highly Active Antiretroviral Therapy). Fusion proteins with the most immunogenic features among
conserved regions can facilitate this achievement in such a variable virus. To achieve the most immunogenic
and also conserved regions, bioinformatics tools are widely used to predict antigens’ features
before applying them.

Objective:
This study aimed at the in vitro evaluation of p24 -Nef fusion protein based on the previous
in silico design to achieve a potential therapeutic subunit vaccine against HIV-1.

Methods:
The truncated form of p24-Nef using AAY flexible linker and the full protein were expressed
and evaluated in the prokaryotic system and confirmed by western blotting. We also used
pcDNA3.1 to transfect Lenti-X 293T cells. Moreover, lentiviral vectors were applied to produce recombinant
virions harboring the genes of interest and cell transduction.

Results:
Both fusion proteins in a truncated and a full form were expressed and confirmed by Anti Nef
polyclonal antibody in western blotting. Recombinant virions were generated and transduced Lenti-X
293T cells confirming by immunofluorescence microscope and p24 ELISA assay kit. Transduced cells
were analyzed by SDS-PAGE and western blotting, which resulted in approved protein expression.

Conclusion:
Fusion protein of p24 and Nef is well expressed in eukaryotic cell lines according to its
pre-evaluated features by bioinformatics tools.
Rapid Determining Contents of the Rhubarb Anthraquinones Compounds by Support Vector Machine Modeling based on Near Infrared Spectra
Authors: Liu Linqi , Luo JInhua , Zhao Chenxi , Zhang Bingxue , Fan Wei , Du Fuyou 
Published: March 2020

Background:
Measuring medicinal compounds to evaluate their quality and efficacy has
been recognized as a useful approach in treatment. Rhubarb anthraquinones compounds (mainly including
aloe-emodin, rhein, emodin, chrysophanol, and physcion) are the main effective components
in purgating drug. In the current Chinese Pharmacopoeia, the total anthraquinones content is designated
as its quantitative quality and control index, while the content of each compound has not been
specified.

Methods:
On the basis of forty rhubarb samples, the correlation models between the near infrared
spectra and UPLC analysis data were constructed using support vector machine (SVM) and partial
least square (PLS) methods, according to the Kennard and Stone algorithm for dividing the calibration/
prediction datasets. Good models mean they have high correlation coefficients (R2) and low root
mean squared error of prediction (RMSEP) values.

Results:
The models constructed by SVM have much better performance than those by PLS methods.
The SVM models have high R2 of 0.8951, 0.9738, 0.9849, 0.9779, 0.9411, and 0.9862 that correspond
to aloe-emodin, rhein, emodin, chrysophanol, physcion and total anthraquinones contents,
respectively. The corresponding RMSEPs are 0.3592, 0.4182, 0.4508, 0.7121, 0.8365, and 1.7910,
respectively. 75% of the predicted results have relative differences being lower than 10%. As for
rhein and total anthraquinones, all of the predicted results have relative differences being lower than
10%.

Conclusion:
The non-linear models constructed by SVM showed good performances with predicted
values close to the experimental values. This can perform the rapid determination of the main medicinal
ingredients in rhubarb medicinal materials.
A villamosenergia-piac egységesítésének esélyei az Európai Unióban
Authors: Sztanko Eva 
Published: March 2020

Az európai belső villamosenergia-piac még nem egységes, de egyes részterületeken már megindult e felé az elmúlt két évtizedben. Egyaránt javult a fogyasztók energiapiaci pozíciója, az európai villamosenergia-piacok likviditása, és felélénkült a határokon átnyúló kereskedelem is. A fokozódó verseny visszafogta az árakat a nagykereskedelmi piacokon. Ugyanakkor a kiskereskedelmi árak és a költségek növekedtek, mind a háztartások, mind az ipar esetében, a fogyasztás visszaeső vagy stagnáló szintje ellenére. Az EU-nak folytatnia kell a villamosenergiapiac átalakítását, szükség van a rugalmas energiarendszerek, versenypiacok kialakítására, a piaci jelzésekre reagáló fogyasztókra és költséghatékony állami/piaci eszközökre az áringadozások kezeléséhez, a beruházások finanszírozásához és a költségnövekedés minimalizálásához. Az Európai Bizottság legújabb átfogó javaslatcsomagja új villamosenergia-piaci modellt kíván megteremteni, kérdés azonban, milyen fogadtatásra talál majd a tagállamok részéről.
Journal of Economic Literature (JEL) kód: Q48
A méltányos kereskedelem hazai kutatási előzményei és magyarországi helyzete
Authors: Toth Eszter 
Published: March 2020

A fair trade egy olyan civil kezdeményezés, amelynek célja, hogy méltányos kereskedelmi feltételeket teremtsen a Harmadik Világ szegény termelői számára,ezáltal esélyt nyújtva számukra egy fenntartható fejlődési modellre kialakítására. A rendhagyó kereskedelmi partnerség a déli országok termelői és az északi félteke vásárlói között a hagyományos nemzetközi kereskedelem szabályait igyekszik megváltoztatni, és egy újszerű alternatívát ajánl helyette. A termékminősítéssel és nemzetközi intézményrendszerrel rendelkező méltányos kereskedelem célja az eddigi domináns gazdasági modell játékszabályainak megváltoztatása, ebben legfőbb eszköze a tudatos és felelősségvállalásra kész fogyasztói réteg elkötelezése. Az irodalomáttekintő cikk a mozgalom eddigi magyarországi eredményeit és a témában végzett kutatásokat igyekszik bemutatni.
Journal of Economic Literature (JEL) kódok: F13, F18, J81, P45
Digitally Enhanced Mentoring for Immigrant Youth Social Capital: Protocol for a Mixed Methods Pilot Study and a Randomized Controlled Trial
Authors: Radlick Rebecca Lynn , Svedberg Petra , Nygren Jens M , Przedpelska Sarah , Gammon Deede 
Published: March 2020

Background
There are large disparities between immigrants and native Norwegians in domains such as health, education, and employment. Reducing such disparities is essential for individual and societal well-being. Social capital is associated with positive effects on these domains, and mentoring programs have the potential to boost social capital. However, few studies have assessed mentoring as a social capital intervention among youth or the potential barriers and facilitators of implementing digitally augmented mentoring.

Objective
The goal of this paper is to describe a protocol for assessing the implementation and effectiveness of a digitally augmented mentoring program for immigrant youth as a health intervention to promote social capital. The two-stage analytical framework for a pilot study followed by a randomized controlled trial (RCT) is presented. The pilot aims to assess program fidelity and make necessary intervention adjustments before the RCT. The RCT aims to assess the effects of the implemented intervention program on social capital and the relationship between program fidelity and effects.

Methods
Both the pilot and RCT will use mixed methods with a process evaluation approach used to structure the intervention and a pre-post test survey component to measure social capital and fidelity of program implementation. Interviews will also be used to enrich the quantitative data from the survey.

Results
The pilot study is scheduled to begin in fall 2019. Based on data analyses in spring 2020, potential adjustments will be made to the intervention, with findings used in preparation for the full-scale RCT study.

Conclusions
Digitally enhanced mentoring programs may be a helpful intervention for providing immigrant youth with tools for increasing their social capital and indirectly improving health outcomes. This protocol provides new knowledge about the implementation and evaluation of such programs.

International Registered Report Identifier (IRRID)
PRR1-10.2196/16472
EVALUATION OF CURRENT SCENARIO OF CANCER DISEASE AT CHATTAGRAM IN BANGLADESH
Authors: Paul Emon , Islam Md. Shahidul 
Published: March 2020

Objective: Now a day Cancer is the furthermost dangerous diseases. It can develop almost anywhere in the body. Cancer is a disease whose treatment process takes too long time and also too costly.
Methods: This is a survey work on cancer due to current increasing of the number of cancer patients in Bangladesh. This evaluation was conceded in Chittagong Medical College Hospital, Bangladesh, from 10th November 2019 to 25th February 2020. Here, 31 cancer patients were evaluated.
Results: In this work, it is observed that most of the cancer patients were female. In this study, it was also observed the cancer was occurred highly at the age of 41-50 years (30%), then age limit 31-40 (20%).Most of the female are bearing ovary cancer (26%) and Breast cancer (29%) and also male are affected by Thyroid cancer (26%). We found that 60% of patients were being treated with chemotherapy alone. Doctors were commonly prescribed of chemo drugs Cisplatin (21%) and Folinic acid (29%).
Conclusion: Government should highlight on the expansion of specific cancer center. Such types of centers can also deliver rehabilitation as well as relaxing care for dangerous cancer patients to release their highdistress.
Peer Review History:
Received 26 February 2020; Revised 7 March; Accepted 9 March, Available online 15 March 2020
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Received file

Average Peer review marks at initial stage: 4.0/10
Average Peer review marks at publication stage: 7.0/10
Reviewer(s) detail:
Name: Dr. Dalia Kamal Zaffar Ali
Affiliation: Modern University for technology and information, Egypt
E-mail: dr.moda88@gmail.com

Name: Dr. Mohammad Tauseef
Affiliation: Department of Pharmaceutical Sciences
College of Pharmacy, Chicago State University
E-mail: mtauseef@csu.edu
Comments of reviewer(s):

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