bluuebunny/crossref_metadata_2025_split huggingface dataset:
A narrative review on sexual wellbeing and dysfunctions: Research in the past 15 years
Authors: Sawant Neena , Vaidyanathan Sreelakshmi , Rao T S Sathyanarayana , Telang Suparna 
Published: December 2024

Background:
Psychosexual health is an important aspect of mental and physical wellbeing. Though Indian culture has a rich history of sexuality, over the years, our population has been reticent in talking about the same. With the advent of technology and new legislations protecting the rights of LGBTQIA population, awareness is also on the rise.

Methods:
This review focuses on research published by Indian authors over the past 15 years, with search of databases like PubMed, Scopus, Google Scholar, and Litmaps to include original articles and case reports.

Results:
Most studies focus on male sexual dysfunctions. Some emerging research showed promise in female sexual dysfunctions, the elderly, and the LGBTQIA population. The majority of research in sexual health continues to concentrate on dysfunctions, primarily prevalence, associations, or risk factors. Several studies investigated various medical/psychiatric comorbidities associated with sexual dysfunctions. A few studies have explored management strategies as well.

Conclusion:
This review highlights the need for a more holistic approach to management to sexual health issues. It further underscores the importance of grassroots-level initiatives working on improving the training of all medical practitioners and postgraduate students, increasing the availability of services for sexual disorders, promoting sexual health research in areas with gaps, and raising awareness in the general population.
Unveiling the landscape of antistigma interventions for individuals with substance use disorders: A scoping review
Authors: Ghosh Abhishek , Sharma Babita , Sood Arshia , Sharma Kshitiz 
Published: December 2024

Background:
Stigma against persons living with substance use disorders (PLSUD) fosters social and health inequities.

Aim:
We aimed to map different populations targeted by antistigma interventions, analyze specific characteristics of these interventions, and identify and categorize the theoretical frameworks used in these interventions.

Methods:
We examined randomized controlled trials and quasi or pre-experimental studies targeting stigma against PLSUD. Using two English databases, our analysis involved mapping study populations, antistigma interventions, and trial characteristics through a narrative synthesis. We adhered to the Workgroup for Intervention Development and Evaluation Research (WIDER) checklist for assessing reporting quality. The Theoretical Domain Framework (TDF) identified intervention domains and constructs of the interventions.

Results:
Of 698 studies, 29 met eligibility, with three from low-middle-income countries: 12 studies addressed the public, 11 self, and 5 structural stigmas. Reduction in stigma or improvements in knowledge of and attitude toward PLSUD was observed in 23 studies. Eight used social contact-based interventions, and one used direct social contact. Other interventions were psychoeducation, collaborative community care and linkage to social services, acceptance and commitment therapy, and gatekeepers’ training. Five focused on injection drug use stigma; others were not substance-specific. Most studies reported the characteristics of the recipients (n = 28), mode of delivery (n = 28), and delivery settings (n = 24). Adherence to delivery protocol was the least reported (n = 5). The number of theoretical domains varied: 18 studies had 1–5 domains, 3 studies had 10, and 8 studies had 6–9 domains.

Conclusion:
Social contact-based interventions show promise for PLSUD; future research must improve the quality of reporting and design theory-informed interventions.
Influence of Light Curing Time on the Bond Strength of Orthodontic Brackets Using Different Light Curing Units – An In vitro Study
Authors: Tripathi Anand A. , Baxi Shalabh , Singhal Manika , Tiwari Anurag , Prasad P. Narayana , Bagde Hiroj 
Published: December 2024

ABSTRACT

Background:
The bond strength of orthodontic brackets is crucial for successful orthodontic treatment. Light curing units (LCUs) play a significant role in this process, with varying light curing times potentially impacting bond strength.

Materials and Methods:
This in vitro study involved 60 extracted human premolars, randomly divided into three groups (n = 20) based on the type of LCU used: halogen, LED, and plasma arc. Each group was subdivided into two subgroups (n = 10) based on light-curing time (10 sec and 20 sec). The brackets were bonded using a standardized adhesive system. The bond strength was tested using a universal testing machine, and the data were statistically analyzed using ANOVA and post-hoc tests.

Results:
The results showed that the bond strength of orthodontic brackets varied significantly with different LUCs and curing times. The halogen LCU group demonstrated a mean bond strength of 12.5 MPa for 10 sec and 15.3 MPa for 20 sec. The LED LCU group showed a mean bond strength of 14.2 MPa for 10 sec and 16.8 MPa for 20 sec. The plasma arc LCU group exhibited a mean bond strength of 13.8 MPa for 10 sec and 17.1 MPa for 20 sec. Statistical analysis revealed that the LCU type and the light curing time significantly affected the bond strength (P < 0.05).

Conclusion:
The bond strength of orthodontic brackets is influenced by the type of LCU and the duration of light-curing.
A Comparative Evaluation of Fracture Resistance of Three Post Systems and Their Mode of Failure: An In-Vitro Study
Authors: Sundesha Manish , Choudhary Anita , Gubrellay Priyanka , Negi Eishita , Chhina Harleen , Jain Omni P. , Patel Nikita 
Published: December 2024

ABSTRACT

Aim:
To analyze the fracture resistance of three post systems and their mechanism of failure.

Materials and Procedures:
Forty-five newly excised human mandibular single-rooted pre-molar, for periodontal or orthodontic reasons, were used. The teeth were separated into three groups (n = 15) based on the post system utilized. Group A had teeth restored with custom cast post; Group B had prefabricated glass fiber posts (Angelus post); and Group C with edelweiss composite post (Edelweiss Post).

Results:
The custom cast posts provided the highest fracture resistance but exhibited more unfavorable fractures. The edelweiss posts exhibited the least fracture resistance.

Conclusion:
Further investigations should be targeted at elucidating the force dynamics of this newer post system.
Premature ovarian insufficiency (POI) in childhood cancer survivors
Authors: Gunasheela Devika , Veerambudhi Akhila Mandyam 
Published: December 2024

Abstract
The advancement in the area of cancer therapy has resulted in an overall increase in the long-term survival rate of cancer survivors, especially in children. These advances in cancer therapy also come with certain long term side effects among the adult survivors of childhood cancers, one of which is reduced fertility. The long-term effects range over a spectrum from life-altering to life-threatening, but infertility is different from others as it not only involves the patients but also their partners and family members. Premature ovarian insufficiency (POI) is one of the delayed ill effects of childhood cancer therapy. It can present as premature menopause in females who retain their ovarian function after cancer therapies. POI was mostly found among women who have previously had Hematopoietic stem cell transplantation (HSCT), abdominal irradiation, central nervous system irradiation and chemotherapy. Multiple efforts have been made to formulate screening recommendations for the late effects of cancer treatment in childhood cancer survivors. The POI surveillance recommendations for female survivors were reviewed in 2016. There still remains a wide gap in knowledge and awareness among oncology providers and the female childhood cancer survivors regarding need for surveillance of gonadal function and timely referral to gynaecologists. The discussion about this effect and counselling of available options of fertility preservation is mostly never done or is missed out. The need for a fertility status assessment at adulthood should be emphasized among most oncology providers who interact with such group of patients and timely referral to a gynaecologist/reproductive medicine specialist should be advised accordingly.
Preliminary evidence of renal function improvement in chronic progressive kidney disease using autologous CD34+ cell therapy: A clinical trial
Authors: Ohtake Takayasu , Sato Tsutomu , Tsukiyama Toshitaka , Muraoka Suguru , Mitomo Ayaka , Maruyama Haruka , Yamano Mizuki , Mochida Yasuhiro , Ishioka Kunihiro , Oka Machiko , Moriya Hidekazu , Hidaka Sumi , Masuda Haruchika , Asahara Takayuki , Kobayashi Shuzo 
Published: December 2024

BACKGROUND
To date, no specific treatment has been established to reverse progressive chronic kidney disease (CKD).
AIM
To evaluate the safety and efficacy of autologous CD34+ cell transplantation in CKD patients who exhibited a progressive decline in renal function.
METHODS
The estimated glomerular filtration rate (eGFR) at the beginning of the study was 15.0-28.0 mL/minute/1.73 m2. After five days of treatment with the granulocyte colony-stimulating factor, mononuclear cells were harvested and CD34+ cells were magnetically collected. CD34+ cells were directly injected into the bilateral renal arteries twice (at 0 and 3 months), and their safety and efficacy were evaluated for 6 months.
RESULTS
Four patients were enrolled and completed the study. Three of four patients showed improvement in eGFR slope (eGFR slope > 0 mL/minute/1.73 m2), with the monthly slope of eGFR (delta eGFR) changing from -1.36 ± 1.1 (pretreatment) to +0.22 ± 0.71 (at 6 months) mL/minute/1.73 m2/month (P = 0.135) after cell therapy. Additionally, intrarenal resistive index (P = 0.004) and shear wave velocity (P = 0.04) were significantly improved after cell therapy. One patient experienced transient fever after cell therapy, and experienced bone pain during granulocyte colony-stimulating factor administration. However, no severe adverse events were reported.
CONCLUSION
In conclusion, our findings suggest that repetitive peripheral blood-derived autologous CD34+ cell transplantation into the renal arteries is safe, feasible, and may be effective for patients with progressive CKD. However, a large-scale clinical trial is warranted to validate the efficacy of repetitive regenerative cell therapy using autologous CD34+ cells in patients with progressive CKD.
Mesenchymal stem cell therapy in atherosclerosis: A bibliometric and visual analysis
Authors: Cheng Xing , Li Ya-Ling , Wang Heng , Zhang Rui-Jing , Fan Ke-Yi , Qi Xiao-Tong , Zheng Guo-Ping , Dong Hong-Lin 
Published: December 2024

BACKGROUND
Mesenchymal stem cells (MSCs) are capable of self-renewal and differentiation, and extensive studies have demonstrated their therapeutic potential in atherosclerosis (AS).
AIM
To conduct a bibliometric analysis of studies on the use of MSC therapy for AS over the past two decades, assess key trends and provide insights for future research directions.
METHODS
We systematically searched the Web of Science Core Collection database for articles published between 1999 and 2023, yielding a total of 556 articles. Visual representation and bibliometric analysis of information and trends were facilitated using CiteSpace, the R package ‘bibliometrix’ and VOSviewer.
RESULTS
The analyzed articles were predominantly from 52 countries/regions, with prominent contributions from China and the United States. A cohort of 3057 authors contributed to these publications, with the works of Libby P distinguished by their influence and citation count. Int J Mol Sci has emerged as the journal with the highest publication volume, prominently disseminating influential papers and identifying citation outbreaks. Furthermore, our analysis identified current research hotspots within the field, focusing on vascular progenitor cells, inflammatory mechanisms, and extracellular vesicles. Emerging research frontiers, such as extracellular vesicles and oxidative stress, have been highlighted as areas of burgeoning interest. Finally, we offer perspectives on the status of research and future directions of MSC therapy in AS.
CONCLUSION
This comprehensive analysis provides valuable insights for advancing scientific research on MSC therapy for AS. By elucidating pivotal trends and research directions, this study aimed to foster innovation and promote the progress of disciplines in this field, thereby contributing to advancing scientific knowledge and clinical practice.
Employability of Beed (Bachelor of Elementary Education) Graduates from 2018-2020: Implication to Sustainable Development Goals
Authors: Vera Jocelyn Sagun-De 
Published: December 2024

Objectives: This paper examined the employability results of Bachelor of Elementary Education (BEED) graduates who specialized in Enhanced General Education from Pangasinan State University, Alaminos City Campus, from 2018 to 2020.

Theoretical Framework: The study was guided by theories of employability and labor market dynamics, emphasizing the influence of educational credentials and skills acquisition on graduates' job prospects.

Method: A descriptive survey methodology was utilized, including questionnaires disseminated via Google Forms and social media sites like Facebook and Messenger. It involves 207 graduate respondents as to their employment status, determinants affecting their employment, and job security.

Results and Discussion: Based on results a proportion of the 2018 graduates (38.03%) had attained employment as private school teachers, or instructors, while 12.68% got permanent items in public schools. Likewise, the 2019 cohort indicated that 16.21% were hired as public-school educators, while 26.12% were engaged in private institutions under probationary status. Graduates of 2020, affected by the pandemic, secured positions as teachers/instructors, sales executives, call center representatives, administrative aides, and microfinance officers in the private sector under contractual agreements.

Research Implications: Hence, it only proved from the results that there is a need for teachers especially in primary education as conduits or agents for ensuring inclusive and quality education and promoting lifelong learning opportunities, especially for the underprivileged and demarcated members of society. Thus, it fosters inclusive, sustainable economic growth and ensures decent work for all.

Originality/Value: This research is unique since it focused on the implications for sustainable development goals for the Bachelor of Elementary Education.
Establishing an Environmental Court in Indonesia: Addressing Legal Challenges for Environmental Justice in Line with SDG 13 and SDG 16
Authors: Jumas  , Maskun  , Wahid AM Yunus , Magassing Abdul Maasba 
Published: December 2024

Objectives: This study examines the challenges facing environmental law enforcement in Indonesia, particularly in achieving environmental justice.

Theoretical Framework: This research is based on environmental justice theory, which emphasizes fair treatment and meaningful involvement of all people in environmental law and policy. Additionally, the principles of sustainable development and constitutional mandates for environmental protection serve as the foundation for analyzing Indonesia's legal framework and its alignment with Sustainable Development Goals (SDGs), particularly SDG 13 and SDG 16.

Method: This study uses a normative legal research approach, analyzing relevant laws, regulations, legal principles, and universal environmental management frameworks to assess Indonesia's current environmental legal structures and the necessity of an Environmental Court.

Results and Discussion: The establishment of an Environmental Court is proposed as a solution to address Indonesia’s environmental law enforcement issues. This court would provide a legal forum for environmental disputes, promoting community access to justice and enhancing public participation in environmental protection. Aligned with SDG 16 (Peace, Justice, and Strong Institutions) and SDG 13 (Climate Action), the court would uphold the constitutional right to a healthy environment, reinforcing Indonesia’s commitment to sustainable development and strengthening its legal framework for environmental justice.

Research Implications: The study suggests that a dedicated Environmental Court could fill a crucial gap in Indonesia’s environmental governance structure.

Originality/Value: This research contributes original insights by proposing the establishment of an Environmental Court in Indonesia, a concept not yet fully explored in existing literature.
Sparking Deeper Understanding: The Impact of Individual Argumentation on Student Understanding in Chemical Kinetic to Support SDG-4 Quality Education
Authors: Yonata Bertha , Suyono  , Azizah Utiya 
Published: December 2024

Objectives: This study explored the individual argumentation activities to improve students’ understanding of chemical kinetics. This study support one of the indicators of SDG-4 that is ensuring all students achieve the knowledge and skills needed to drive sustainable development.

Theoretical Framework: Argumentation is one of several activities using higher ordert thinking skills. Students were engaged in an independent activity that encouraged them to develop arguments related to chemical kinetics concepts using an independent argumentation worksheet.

Method: Nineety-six students participated in a single-group pre-post design, engaging in a structured individual argumentation exercise that focused on four key topics in chemical kinetics: reaction rate, half-life, catalysts, and reaction mechanisms.

Results and Discussion: The Wilcoxon Signed-Rank test revealed a statistically significant increase in students’ scores from pretest to posttest (Z = -8.520, p < .000), indicating the effectiveness of the argumentation intervention. The results showed that students who engaged in the independent argumentation activity showed significant improvements in their cognitive completeness.

Research Implications: These findings suggest that incorporating argumentation into independent learning can result in significant learning gains, leading to deeper conceptual understanding through critical thinking skills.

Originality/Value: This study highlights the potential of argumentation as a pedagogical tool to move beyond memorization and foster deeper conceptual understanding in chemical kinetics. Thus, independent argumentation can be considered as an effective strategy in chemistry learning to help students achieve deeper understanding and better cognitive mastery learning.
Tracking Education Transformation Towards Sustainable Development Goals: A Bibliometric Review on the Influence of Socioeconomic Factors in the Education Ecosystem
Authors: Ali Mohamad , Waston  , Tamami Fauziyah Qurrota A’yun , Rahmawati Siti , Muthoifin  , Elbanna Mariam , Mahmudulhassan  , Andri Nirwana AN  
Published: December 2024

Objective: This study aims to map the development and direction of research on socioeconomic factors within the education ecosystem, focusing on publications indexed in the Scopus database. It seeks to provide an accessible literature overview for researchers in this field and offer recommendations for future research.

Method: The research used to Using a quantitative approach with bibliometric data analysis techniques, this research examines all publications indexed in Scopus from 1990 to 2023 related to socioeconomic factors in the education ecosystem. Data were analyzed using Excel and R/R-Studio, and VOSViewer was employed for visual analysis of keyword occurrences and document citations.

Results: A total of 772 relevant publications matching the function, subject, and study criteria were identified. The findings reveal an annual growth rate and distribution of publications by scientific field and annual publication volume. This study is limited to data indexed in Scopus and does not account for other national or international databases.

Contribution: This article provides a concise literature review accessible to researchers in the field of socioeconomic factors in the education ecosystem and offers recommendations for future research development.
Stress Management in Higher Education: The Role of On-line Yoga and Digital Learning
Authors: Sudhan P. , Parveen S. Jahira 
Published: December 2024

Aim and Objective: The National Education Policy (NEP) 2020 supports blended learning, allowing up to 40% of coursework online to enhance accessibility and inclusivity, with online yoga sessions offering stress relief for higher education students, especially during the pandemic. The study aims to investigate the effectiveness of online yoga as a stress management tool for higher education students, assessing its impact on reducing perceived stress levels. Additionally, it seeks to evaluate how online and digital learning methods in yoga can foster mindfulness and resilience against academic stress, in line with the NEP 2020’s emphasis on blended and accessible education.

Design/Methodology: The study employed a pre- and post-test experimental design involving 30 higher education students from SRM Institute of Science and Technology. Participants were divided into an experimental group, which underwent a 12-week online yoga program, and a control group, which received no intervention. Stress levels were measured using the Perceived Stress Scale (PSS) before and after the intervention, with a follow-up assessment three months later. Data analysis was performed using SPSS 19.0, specifically the Wilcoxon Signed-Rank Test, to compare stress level changes within and between groups.

Results: The Wilcoxon Signed-Rank Test revealed a statistically significant reduction in stress levels in the yoga group (Z = -3.413, p = 0.001), with all participants showing improvement. In contrast, the control group exhibited mixed results, with no significant change in stress levels (Z = -0.345, p = 0.730). This indicates that the online yoga program was effective in reducing stress, likely due to enhanced mindfulness practices, such as self-compassion, reduced self-criticism, and better emotional regulation.

Findings: The findings support the role of online and digital learning for yoga in managing academic stress, providing students with practical tools like asanas, pranayama, and meditation. Additionally, mindful internet and social media use were promoted as part of the program, offering a holistic approach to stress relief. Incorporate online yoga programs into the higher education curriculum to address stress and promote well-being, aligning with the NEP’s focus on blended learning. Mindfulness practices, including self-compassion and emotional regulation, should be integrated into stress management strategies . Expanding the yoga program to a larger, diverse student body will validate its effectiveness across academic settings.