bluuebunny/crossref_metadata_2025_split huggingface dataset:
Work in Roman Catholic Thought
Authors: Himes Kenneth R. 
Published: October 2020

AbstractThis essay examines the idea of work in the Catholic social tradition. Following introductory comments about the Christian vision of work found in the writings of St. Paul and other early Christian authors, the essay provides seven claims as a summary of how work is treated in modern Catholic social teaching. Based on those summary claims, a vision of what good work in the Catholic tradition looks like is then developed. Finally, the phenomenon of the “gig economy” is presented as a contemporary threat to the meaning of good work.
Artificial Intelligence and Human Flourishing
Authors: Clark Charles M. A. , Gevorkyan Aleksandr V. 
Published: October 2020

AbstractThe polarization of the debate about artificial intelligence (AI) pulls in two mutually exclusive directions of either complete takeover of future jobs by omnipotent algorithms or an absolute bliss with robots at work while humans reap the benefits of endless vacation. Add this to conflicting views of work as either a disutility to be minimized or as an essential component in human flourishing, and it is no wonder a wide range of views are expressed on AI and human flourishing. The literature, from Smith to Keynes and beyond, offers some initial methodological guidance. Still, the true social and economic implications of an AI‐type environment in production and labor markets are yet to be fully understood. This article argues that neither of the predictions are realistic. Instead, the global economy may be passing, albeit at a faster speed, through a phase of technological change, similar to those experienced before. While a nuanced balance is emerging, with an emphasis on human skills in future employment, the benefits may not be equitably distributed, as equality of opportunities for human development may not be reachable, though visible, in the AI‐driven society. Hence, as firms seek efficiency gains, much weight is shifted onto governments and quasi‐private entities in maintaining decent living standards conducive to human flourishing in unprecedented times of the COVID‐19 pandemic. The article reviews various popular concerns and advances new public policy measures aimed at tackling some of the immediate fears of automation.
The role of institutions and immigrant networks in firms’ offshoring decisions
Authors: Moriconi Simone , Peri Giovanni , Pozzoli Dario 
Published: October 2020

Abstract. The offshoring of production by firms has expanded dramatically in recent decades, increasing their potential for economic growth. What determines the location of offshore production? How do countries’ policies and characteristics affect a firm's decision about where to offshore? Do firms choose specific countries because of the countries’ policies or because they know them better? In this paper, we use a rich dataset on Danish firms to analyze how decisions to offshore production depend on the institutional characteristics of the country and firm‐specific bilateral networks. We find that institutions that reduce credit risk and corruption increase the probability that firms will offshore there, while those that increase regulation in the labour market decrease this probability. We also show that a firm's probability of offshoring increases with the share of its employees who are immigrants from that country of origin. Finally, our analysis reveals that the negative impact of institutions that hinder offshoring is attenuated by a strong bilateral network of foreign workers.
Trichoblastic carcinosarcoma in a 34‐year‐old woman with histopathologic and molecular analysis, including re‐demonstration of a CDKN2A p.(R58*) mutation
Authors: Kim Chris , Brown Angela , Osipov Vladimir 
Published: October 2020

AbstractTrichoblastic carcinosarcomas are rare, adnexal‐type cutaneous carcinosarcomas that are thought to be related histogenetically to trichoblastomas, yet in which both the epithelial and stromal components show features of malignancy. Ten cases have been described in the literature thus far, with a predilection for the head and neck of older males. We present a case of cutaneous carcinosarcoma in sun‐damaged skin of a 34‐year‐old woman showing features of a trichoblastic carcinosarcoma, with histopathologic analysis along with targeted next‐generation sequencing of 50 cancer‐associated genes. Two pathogenic variants in TP53 were identified, p.(R158C), p.(R273P), along with a likely pathogenic variant CDKN2A, p.(R58*). In particular, it is noted that the CDKN2A p.(R58*) missense mutation has been described in two previous cases of cutaneous carcinosarcomas, including a case of trichoblastic carcinosarcoma.
The impact of nationwide alcohol ban during the COVID‐19 lockdown on alcohol use‐related internet searches and behaviour in India: An infodemiology study
Authors: Singh Swarndeep , Sharma Pawan , Balhara Yatan Pal Singh 
Published: October 2020

AbstractIntroduction and AimsTo control the spread of COVID‐19, India imposed a nationwide lockdown in phases including lockdown 1.0 (25 March–14 April) and 2.0 (15 April–3 May). Among other restrictions, it involved a complete ban of alcohol sales. We aimed to examine and interpret the changes in online search interest for keywords representing different alcohol‐related themes during the lockdown period in India.Design and MethodsData were extracted using the framework described for using Google Trends in health‐related research. The list of alcohol‐related search queries was prepared for four broad themes: types of alcoholic beverages consumed; means of accessing alcohol; problems experienced due to break in alcohol supply; and help‐seeking for alcohol use disorders. The mean relative search volumes across three time periods (pre‐lockdown; lockdown 1.0; lockdown 2.0) were compared using spss version 23.0.ResultsA significant increase in online search interest for keywords related to the procurement of alcohol was observed in lockdown 1.0 but not during lockdown 2.0, compared with pre‐lockdown. A significant increase in online search interest for alcohol withdrawal was observed during lockdown 1.0 compared to the pre‐lockdown period. A significant increase in online search interest for keywords representing benzodiazepines was observed in lockdown 2.0.Discussion and ConclusionsIndian internet users exhibited significantly increased online interest for alcohol‐related searches during lockdown. It seems that the challenges associated with offering interventions for alcohol use‐related problems are likely to continue once the lockdown is lifted and people have the option to access alcohol and treatment services freely.
Nested variational autoencoder for topic modelling on microtexts with word vectors
Authors: Trinh Trung , Quan Tho , Mai Trung 
Published: October 2020

AbstractMost of the information on the Internet is represented in the form of microtexts, which are short text snippets such as news headlines or tweets. These sources of information are abundant, and mining these data could uncover meaningful insights. Topic modelling is one of the popular methods to extract knowledge from a collection of documents; however, conventional topic models such as latent Dirichlet allocation (LDA) are unable to perform well on short documents, mostly due to the scarcity of word co‐occurrence statistics embedded in the data. The objective of our research is to create a topic model that can achieve great performances on microtexts while requiring a small runtime for scalability to large datasets. To solve the lack of information of microtexts, we allow our method to take advantage of word embeddings for additional knowledge of relationships between words. For speed and scalability, we apply autoencoding variational Bayes, an algorithm that can perform efficient black‐box inference in probabilistic models. The result of our work is a novel topic model called the nested variational autoencoder, which is a distribution that takes into account word vectors and is parameterized by a neural network architecture. For optimization, the model is trained to approximate the posterior distribution of the original LDA model. Experiments show the improvements of our model on microtexts as well as its runtime advantage.
Internationalization of SMEs in the Baltic Sea Region: Barriers of cross‐national collaboration considering regional innovation strategies for smart specialization
Authors: Mueller‐Using Susanne , Urban Wieslaw , Wedemeier Jan 
Published: October 2020

AbstractThis paper provides new evidence on barriers that hamper small and medium‐sized enterprises (SME) in the Baltic Sea Region (BSR) to establish international collaboration. Our analysis makes use of collected data concerning internationalization of SMEs in seven BSR countries. Our logistic multivariate regression model, which we applied after selecting relevant variables using the LASSO method, indicates a significant positive effect for the entities´ demand in support to acquire clients as well as the absence of foreign markets operations. A significant adverse effect is found for cooperation agreements as a support tool for internationalization as well as the interest to participate in an innovation and internationalization system. SMEs rather desire their internationalization capacity building than direct support in acquiring clients. Overall, our results support the hypothesis that strengthening cross‐national collaborations and establishing appropriate support programs are important toward innovativeness and competitiveness among SMEs in the BSR. Smart Specialization Strategies (S3) could provide a framework for building cross‐national collaborations.
Religiosity and food waste reduction intentions: A conceptual model
Authors: Elhoushy Sayed , Jang SooCheong (Shawn) 
Published: October 2020

AbstractAre religious consumers less wasteful? If so, to what extent and by what mechanisms does religiosity motivate consumers to reduce food waste? To address these questions, this study proposes a conceptual model and evaluates it empirically using PLS‐SEM and data from 583 consumers. The results reveal that religiosity encourages food waste reduction. Specifically, religiosity is positively related to consumer attitudes, activism and personal and subjective norms to reduce food waste. Consumers’ activism and personal norms are significant mediating mechanisms that convey the impact of religiosity on food waste reduction intentions. Interestingly, however, consumers’ attitudes and subjective norms show no significant effects on their food waste reduction intentions. In addition, perceived behavioural control (PBC) appears to be an important determinant of consumer intentions, but it plays a direct role rather than a moderating role. These results extend the previous literature by (a) proposing novel intervening mechanisms to explain the understudied religiosity‐consumer behaviour relationship and (b) shedding light on the controversy regarding the additive versus moderating effect of PBC. Ultimately, this study provides a basis for religious‐based interventions for policy makers and marketers as well as ideas to motivate food waste reduction at the consumer level.
Crosstalk between circadian rhythms and the microbiota
Authors: Pearson James Alexander , Wong Florence Susan , Wen Li 
Published: October 2020

SummaryCircadian rhythms influence daily molecular oscillations in gene/protein expression and aspects of biology and physiology, including behaviour, body temperature and sleep–wake cycles. These circadian rhythms have been associated with a number of metabolic, immune and microbial changes that correlate with health and susceptibility to disease, including infection. While light is the main inducer of circadian rhythms, other factors, including the microbiota, can have important effects on peripheral rhythms. The microbiota have been of significant interest to many investigators over the past decade, with the development of molecular techniques to identify large numbers of species and their function. These studies have shown microbial associations with disease susceptibility, and some of these have demonstrated that alterations in microbiota cause disease. Microbial circadian oscillations impact host metabolism and immunity directly and indirectly. Interestingly, microbial oscillations also regulate host circadian rhythms, and the host circadian rhythms in turn modulate microbial composition. Thus, it is of considerable interest and importance to understand the crosstalk between circadian rhythms and microbiota and especially the microbial influences on the host. In this review, we aim to discuss the role of circadian microbial oscillations and how they influence host immunity. In addition, we discuss how host circadian rhythms can also modulate microbial rhythms. We also discuss potential connections between microbes and circadian rhythms and how these may be used therapeutically to maximize clinical success.
Urinary sodium excretion and its association with blood pressure in Nigeria: A nationwide population survey
Authors: Odili Augustine N. , Chori Babangida S. , Danladi Benjamin , Nwakile Peter C. , Okoye Innocent C. , Abdullahi Umar , Zawaya Kefas , Essien Ime , Sada Kabiru , Nwegbu Maxwell M. , Ogedengbe John O. , Aje Akinyemi , Isiguzo Godsent C. 
Published: October 2020

AbstractAssessment of level of salt intake in a population is the first step toward planning strategies aimed at salt reduction. As a surrogate of salt intake, we measured a single 24‐hour urine sodium (uNa) of free‐living 2503 adults in a nationally representative sample of Nigerians drawn from 12 rural and urban communities; and evaluated the community‐level association of uNa with blood pressure (BP). Overall, the median (interquartile range (IQR)) of uNa was 99 (105) mmol, ranging from 23.8 (32.4) in rural north‐central to 172.8 (131.0) mmol in urban northwestern region. Daily uNa was significantly higher (p < .001) in men compared to women (107.1 vs 93.9 mmol); and urban compared to rural dwellers (114.9 vs 86.0mmol). About one‐half of participants excreted uNa in excess of recommended daily maximum value (86mmol). In a model adjusted for age, sex, body mass index (BMI), level of education, place of residence, and use of antihypertensive medication; being a man (odds ratio, OR 1.69, 95% confidence Interval CI, 1.21‐2.37, p = .002) and being < 60 years of age (OR 1.74, 95% CI 1.23‐2.45, p = .002), were associated with excreting higher than recommended uNa. In a fully adjusted model of the community‐level analysis, urinary sodium, potassium, and sodium‐to‐potassium ratio each showed no significant independent association with both systolic and diastolic BPs. Among adult Nigerians, the median daily uNa excretion was 99 mmol and it had no significant association with blood pressure indices.
Glycemic control before admission is an important determinant of prognosis in patients with coronavirus disease 2019
Authors: Liu Li , Wei Wang , Yang Kun , Li Shengzhong , Yu Xuefeng , Dong Chen , Zhang Benping 
Published: October 2020

AbstractAims/IntroductionThis study aimed to explore the association between glycemic control before admission with severity and mortality of coronavirus disease 2019, and tried to reveal the mechanism.Materials and MethodsA total of 77 inpatients were grouped into sufficient control group (glycated hemoglobin [HbA1c] <6.5%, n = 49) and insufficient control group (HbA1c ≥6.5%, n = 28). Regression models were used to analyze the clinical data.ResultsCompared with patients with HbA1c <6.5, patients with HbA1c ≥6.5 showed higher heart rate (101 vs 89 b.p.m., P = 0.012), lower percutaneous oxygen saturation (93 vs 97%, P = 0.001), higher levels of multiple indicators of inflammation, such as white blood cell count (7.9 vs 5.9 × 109/L, P = 0.019), neutrophil count (6.5 vs 4.1 × 109/L, P = 0.001), high‐sensitivity C‐reactive protein (52 vs 30 mg/L, P = 0.025) and serum ferritin (1,287 vs 716 μg/L, P = 0.023), as well as lower levels of lymphocyte count (0.7 vs 0.8 × 109/L, P = 0.049) at hospital admission. Thus, patients with HbA1c ≥6.5 were more likely to develop secondary respiratory infections (25 [89%] vs 33 [67%], P = 0.032) and acute respiratory distress syndrome (17 [61%] vs 14 [29%], P = 0.006) than patients with HbA1c <6.5, resulting in a higher proportion of critically ill patients (19 [68%] vs 18 [37%], P = 0.009) and non‐survivors (13 [46%] vs 11 [22%], P = 0.029). After adjustment for potential risk factors, HbA1c was independently associated with in‐hospital death.ConclusionHbA1c was an independent risk factor for poor outcomes in coronavirus disease 2019 patients. Severe pulmonary infection and consequent acute respiratory distress syndrome might be the primary causes of death in insufficient glycemic control patients.
A position paper on the management of itch and pain in atopic dermatitis from the International Society of Atopic Dermatitis (ISAD)/Oriented Patient‐Education Network in Dermatology (OPENED) task force
Authors: Misery L. , Belloni Fortina A. , El Hachem M. , Chernyshov P. , von Kobyletzki L. , Heratizadeh A. , Marcoux D. , Aoki V. , Zaniboni M.C. , Stalder J.‐F. , Eichenfield L.F. 
Published: October 2020

AbstractAtopic dermatitis (AD) is a disease that can have a high impact on quality of life, especially due to itch and skin pain. This paper utilizes expertise from members of the International Society of Atopic Dermatitis (ISAD)/Oriented Patient‐Education Network in Dermatology (OPENED) task force to review the epidemiology, pathophysiology and exacerbating factors of itch and pain in atopic dermatitis. General principles of treatment are provided, as well as a more detailed evaluation of topical and systemic therapies. Educational and psychological approaches to itch and pain in atopic dermatitis are proposed, along with expert recommendations for the management of itch and pain in atopic dermatitis.
Offspring sex ratios are stable across the life course inDrosophila simulans
Authors: Archer C. Ruth , Carey Matthew Robert , Noda Tomohito , Store Stefan J. , Hosken David J. 
Published: October 2020

AbstractWithin populations, adult sex ratios influence population growth and extinction risk, mating behaviours and parental care. Sex ratio adjustment can also have pronounced effects on individual fitness. Accordingly, it is important that we understand how often, and why, offspring sex ratios deviate from parity. InDrosophila melanogaster, females appear to improve their fitness by producing fewer sons when paired with older males. However, facultative sex ratio adjustment inD. melanogasteris controversial, and our understanding of how sex ratio skew affects fitness is hampered by pronounced sexual conflict in this species. Additionally, it is unclear whether maternal age or quality interacts with paternal age to influence offspring sex ratios. Here, we test whether offspring sex ratios vary as a function of maternal quality, and maternal and paternal age inDrosophila simulans, a sister species ofD. melanogasterthat lacks overt sexual conflict. We find that offspring sex ratios are slightly male‐biased overall, but constant across the female life course, and independent of female quality, or paternal age. To really understand if, how and when females skew offspring sex ratios, we need studies linking offspring sex ratios to paternal and maternal phenotypes that are predicted to shift optimal investment in sons and daughters.
Ovarian fluid proteome variation associates with sperm swimming speed in an externally fertilizing fish
Authors: Johnson Sheri L. , Borziak Kirill , Kleffmann Torsten , Rosengrave Patrice , Dorus Steve , Gemmell Neil J. 
Published: October 2020

AbstractSperm velocity is a key trait that predicts the outcome of sperm competition. By promoting or impeding sperm velocity, females can control fertilization via postcopulatory cryptic female choice. In Chinook salmon, ovarian fluid (OF), which surrounds the ova, mediates sperm velocity according to male and female identity, biasing the outcome of sperm competition towards males with faster sperm. Past investigations have revealed proteome variation in OF, but the specific components of OF that differentially mediate sperm velocity have yet to be characterized. Here we use quantitative proteomics to investigate whether OF protein composition explains variation in sperm velocity and fertilization success. We found that OF proteomes from six females robustly clustered into two groups and that these groups are distinguished by the abundance of a restricted set of proteins significantly associated with sperm velocity. Exposure of sperm to OF from females in group I had faster sperm compared to sperm exposed to the OF of group II females. Overall, OF proteins that distinguished between these groups were enriched for vitellogenin and calcium ion interactions. Our findings suggest that these proteins may form the functional basis for cryptic female choice via the biochemical and physiological mediation of sperm velocity.
Publication and associated factors of clinical trials registered in Peru
Authors: Heredia Paula , Alarcon‐Ruiz Christoper A. , Roque‐Roque Joel Sack , De La Cruz‐Vargas Jhony A. , Quispe Antonio M. 
Published: October 2020

AbstractObjectiveWe aim to determine the percentage of publication and its associated factors of clinical trials (CTs) registered in Peru.MethodsUsing a cross‐sectional study design, we assessed CTs registered at the CT's Peruvian Registry (REPEC) during the 2011‐2016 period, and evaluated its percentage of publication and associated factors. We used a bibliographic search algorithm to determine if the CTs were published and assessed the associated factors by using a Cox regression to estimate the adjusted hazard ratios (aHR) as the magnitude of association of interest.ResultsWe analyzed 228 CTs, of which 63% were published. The regression analysis identified the year of registration (aHR 2012 = 1.15 [0.58‐2.27]; aHR 2013 = 0.45 [0.21‐0.95]; aHR 2014 = 0.89 [0.43‐1.82]; aHR 2015‐2016 = 0.16 [0.05‐0.58]), total number of participants (aHR = 1.12; 1.05‐1.18), and phase III‐IV (aHR = 2.15; 0.1.16‐4.03) as factors associated with the publication of the CTs.ConclusionsThe percentage of publication of CTs executed in Peru is insufficient, and it increases the older the year of its registration in the REPEC, mayor of the number of participating countries, and if it is a phase III or IV study.