bluuebunny/crossref_metadata_2025_split huggingface dataset:
Governance in Crisis. Examining the Role of TSOs in Asylum Seekers Reception in France and Italy
Authors: Trasciani Giorgia 
Published: December 2024

Abstract
Although third sector organizations (TSOs) played a vital role in supporting public authorities during the European migration crisis, their involvement in governance structures remains underexplored. This paper examines the evolving relationships between TSOs and public authorities in this sector, focussing on the governance shifts triggered by the crisis. By comparing Italy and France – two countries with distinct roles and responses – the study reveals a convergence in their crisis management strategies and the resulting impact on TSOs. Despite initial differences, both nations experienced a marketization of relations, transforming service provision and governance models. This paper analyzes the mechanisms regulating the crisis and their effects on the roles and interactions of key actors. The comparative analysis underscores a broader trend toward the normalization of crisis response systems, providing critical insights into the future of governance models in migration management.
Assessing the soil physical and chemical properties of long-term pomelo orchard based on tree growth
Authors: Linh Tran Ba , Thang La Cao , Khoi Chau Minh , Phuong Nguyen Thi Kim , Thuc Le Vinh 
Published: December 2024

Abstract
The investigation in three groups of pomelo trees (good, average, bad) was conducted. Each group included 15 orchards. The number of soil samples collected for analysis is 15 samples × 2 depths (0–15 cm and 15–30 cm) × 3 groups of plants = 90 soil samples. The results indicated that the soil texture of the good pomelo orchard group and the average pomelo orchard group is silty clay loam, and the bad pomelo orchard group has a silty clay. The average pH value in the bad pomelo orchard group is lower than the average pomelo orchard group and the good pomelo orchard group at both soil depths of 0–15 cm and 15–30 cm. The soil EC of the three groups of pomelo orchards is not different at depths of 0–15 cm and 15–30 cm and does not affect the plants. The average organic matter content at both soil depths 0–15 cm and 15–30 cm of the good pomelo orchard group shows the highest organic matter value. Soil bulk density in the group of bad pomelo orchards had the highest value at both depths of 0–15 cm and 15–30 cm. The porosity of the good pomelo orchard group has the highest value at two depths, 0–15 cm and 15–30 cm. Field capacity of good pomelo orchards have the highest values at both depths of 0–15 cm and 15–30 cm. The K
sat at a depth of 0–15 cm of the good pomelo orchard group is quite slow, while the average pomelo orchard group and the bad pomelo orchard group are at a slow level. The bad physical and chemical properties had negative effects on pomelo growth.
Interplay of cell death pathways and immune responses in ischemic stroke: insights into novel biomarkers
Authors: Daneshpour Arian , Shaka Zoha , Rezaei Nima 
Published: December 2024

Abstract
Stroke is a severe neurological disease and a major worldwide issue, mostly manifesting as ischemic stroke (IS). In order to create effective treatments for IS, it is imperative to fully understand the underlying pathologies, as the existing therapeutic choices are inadequate. Recent investigations have shown the complex relationships between several programmed cell death (PCD) pathways, including necroptosis, ferroptosis, and pyroptosis, and their correlation with immune responses during IS. However, this relationship is still unclear. To address this gap, this review study explored the cellular interactions in the immune microenvironment of IS. Then, to validate prior findings and uncover biomarkers, the study investigated bioinformatics studies. Several pathways, including nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), Toll-like receptor 4 (TLR4), and receptor-interacting protein kinase (RIPK), were involved in PCD-immune interactions. The bioinformatics studies reported key biomarkers such as glutathione peroxidase 4 (GPX4), NOD-like receptor family pyrin domain containing 3 (NLRP3), gasdermin D (GSDMD), and TLR4, which have important implications in ferroptosis, cuproptosis, pyroptosis, and necroptosis respectively. These biomarkers were associated with PCD mechanisms such as oxidative stress and inflammatory reactions. The immune infiltration analysis consistently revealed a significant correlation between PCD pathways and detrimental immune cells, such as neutrophils and γδ T cells. Conversely, M2 macrophages and T helper cells showed protective effects. In conclusion, considering the intricate network of interactions between immune responses and PCD pathways, this study emphasized the necessity of a paradigm shift in therapeutic approaches to address the injuries that are related to this complex network.
Dynamic Panel Threshold Spatial Durbin Model with an Application to the Relationship between Financial Development and Green Growth
Authors: Wei Lili , Zhang Chunli 
Published: December 2024

Abstract
This paper studies computation, estimation, inference and specification testing in dynamic panel threshold spatial Durbin (DPTSD) model with multiple thresholds. We first develop a new Markov chain Monte Carlo (MCMC) based algorithm to jointly estimate the threshold parameters and simultaneously construct the confidence intervals for the parameters, after suggesting a within-group spatial two-stage least squares estimator. We then construct test statistics for threshold effect and the number of thresholds. Monte Carlo experiments indicate that the proposed estimator and tests have desired performance in finite samples. We finally apply the DPTSD model to investigate the relationship between financial development and green growth, and find that the empirical results based on the DPTSD model are quite different from these based on the dynamic panel threshold model.
When Data “Screams,” Women Speak with Their Own Voices
Authors: Skórzyńska Izabela 
Published: December 2024

This is an extended review of Violence and Gender Disparities against Women: A Global Scenario, edited by Anupama Vohra, Jasbir Singh, Parveen Kumari, and Barbara Wejnert (Punjab, India: White Falcon, 2022), considering the multicultural and multi-perspective nature of its authors’ research on gender disparities violence and against women and girls.
The Western perspective on this pressing problem, dominant in public discourse, desensitizes us to the historical and socio-cultural aspects of violence against women and girls and its local specificity. The reviewed book is an attempt to expand this perspective to the Asian countries in a glocal approach, the result of collectively conducted and presented research effects “from home.” Thus the book is the result of mapping the issues related to violence against women and girls different regions of the world. It is also an interventionist publication that points out what we as societies still have to do to address gender violence.
Notions of Nobility in the 16th Century Grand Duchy of Lithuania: Lineage and Virtue
Authors: Čižauskas Karolis 
Published: December 2024

The aim of this text is two-fold. Firstly, a general view of terminological difficulties arising when attempting to name nobility as a whole is presented with the main issue to be faced is the fact that terms such as ‘bajorija’ (a Lithuanian term) or ‘szlachta’ (a Polish one) simultaneously denote a specific and smaller subclass of nobility. Therefore, the Lithuanian neologism ‘kilnuomenė’ has been presented and introduced. It is justified as etymologically bearing two significant notions which were core to the nobility – that of lineage plus nobleness (by nobility, we mean here a ‘noble’ quality of personality character, a virtue). Secondly, departing from this proposed concept of nobility, a historical enquiry and analysis have been carried out whose main purpose was that of demonstrating how both lineage and nobleness (via virtue) functioned in defining membership in the group and acting as an important element of self-representation.
Implementação do Novo Ensino Médio na Rede Estadual de Ensino de Pernambuco
Authors: Silva Luanna Ferreira da , Guimarães Edilene Rocha 
Published: December 2024

Objetiva-se analisar as orientações para implementação do Novo Ensino Médio nos documentos normativos nacionais e da Rede Estadual de Ensino de Pernambuco. A metodologia utilizada tem abordagem qualitativa e seguiu o método da pesquisa documental. O tratamento dos dados se deu por meio da análise de conteúdo categorial. Os resultados foram agrupados em categorias com orientações para: implementação do Novo Ensino Médio; Currículo do Ensino Médio de Pernambuco, Itinerários Formativos e suas Trilhas. As orientações dos documentos normativos definem uma abordagem pedagógica com base na interdisciplinaridade, na autonomia, no protagonismo e na inovação, buscando integrar os Itinerários Formativos a quatro eixos estruturantes: investigação científica; processos criativos; mediação e intervenção sociocultural; e empreendedorismo, com vistas a desenvolver habilidades diversas para a formação integral. Entretanto, concluiu-se que a atual Arquitetura do Currículo do Novo Ensino Médio ofertado nas escolas estaduais de Pernambuco promove um retrocesso na formação integral e omnilateral dos estudantes.
ATP-Gated P2X7-Ion Channel on Kidney-Resident Natural Killer T Cells and Memory T Cells in Intrarenal Inflammation
Authors: Junge Marten , Liaukouskaya Nastassia , Schwarz Nicole , Pinto-Espinoza Carolina , Schaffrath Alessa Z. , Rissiek Björn , Krebs Christian F. , Rattay Guido , Mittrücker Hans-Willi , Tomas Nicola M. , Nicke Annette , Haag Friedrich , Huber Tobias B. , Meyer-Schwesinger Catherine , Koch-Nolte Friedrich , Wanner Nicola 
Published: December 2024

Key Points

Parenchymal T cells in the kidney expressed much higher levels of P2X7 than vascular T cells.P2X7-blocking nanobodies uncover a large fraction of kidney-resident natural killer T and tissue-resident memory T cells.These cells were lost during cell preparation because of activation of P2X7 by NAD+ released from damaged cells, unless blocked by nanobodies.

Background
The P2X7 ion channel, a key sensor of sterile inflammation, has been implicated as a therapeutic target in GN, and P2X7-antagonistic nanobodies can attenuate experimental GN. However, little is known about the expression of P2X7 on renal immune cells.

Methods
We used conventional immunofluorescence of kidney sections and intraperitoneal injection of nanobodies in mice followed by flow cytometry analysis of parenchymal T cells and RNA sequencing to elucidate the expression and function of P2X7 on parenchymal and vascular immune cells in the mouse kidney.

Results
Our study showed that parenchymal T cells, including a large subset of natural killer T cells and CD69+ tissue-resident memory T cells, display much higher cell surface levels of P2X7 than vascular T cells. After a single intraperitoneal injection of P2X7-blocking nanobodies, P2X7 on parenchymal T cells was fully occupied by the injected nanobodies within 30 minutes. This resulted in an effective protection of these cells from nicotinamide adenine dinucleotide–induced cell death during cell preparation. Conversely, systemic injection of nicotinamide adenine dinucleotide that mimics sterile inflammation results in the selective depletion of P2X7hiCD69hi T cells from the kidney parenchyma.

Conclusions
Our study uncovered a novel purinergic regulatory mechanism affecting kidney-resident T-cell populations.
Features of the course of non‑small cell lung cancer and the percentage of lymphocytes in the blood of patients who had recovered from COVID‑19
Authors: Zhukova G. V. , Frantsiyants E. M. , Kharagezov D. A. , Shikhlyarova A. I. , Kaplieva I. V. , Mirzoyan E. A. , Milakin A. G. , Lisunova Z. P. , Avanesova K. A. 
Published: December 2024

Purpose of the study. This study aimed to identify the characteristics of the course of cell lung cancer (LC) and the information content of the indicators of the adaptation status of patients of different sexes who had COVID‑19, confirmed by PCR diagnostic results before the start of antitumor treatment. Patients and methods. We have studied traditional clinical and laboratory parameters, and the white blood cell count in patients with non‑small cell LC st. I–III, men (59) and women (32) aged 36–75 years. The main groups included 32 men and 16 women who had COVID‑19, confirmed by real‑time PCR, 2–9 months before hospitalization. Patients in the control groups denied having a history of diagnosed COVID‑19. Before the start of antitumor treatment, the percentage of lymphocytes in the blood was assessed. Cases of LC progression and mortality within a year after antitumor treatment were noted. Results. In men of the main group a 2.7‑fold increase (p < 0.05) in cases of early lung cancer stagings with a simultaneous tendency towards an increase in the number of incidences of metastasizing and mortality within a year after inpatient treatment in comparison with control indexes were observed. Signs of disease severity worsening and a decrease in the effectiveness of treatment were observed without significant changes in the ratio of the patients with tumors of various stagings in female patients. In patients of the main groups, a disturbance of the correspondence between the percentage of lymphocytes and the prevalence and dynamics of the malignant process was noted. In men of the main group who died within the first year after the end of antitumor treatment, the percentage of lymphocytes before the start of treatment reached 28–45 %, corresponding to antistress adaptational reactions, 4 times more often than in the control group (p < 0.01) Conclusion. COVID‑19 flow before the start of LC treatment contributes to a decrease in the body's antitumor resistance and a violation of the informativeness of the percentage of blood lymphocytes as an indicator of adaptation status. Changes depend on sex. In women, the observed changes reflected an aggravation of the malignant process and systemic disorders, as well as a decrease in the effectiveness of treatment. In men, a sharp increase in the number of cases of one year mortality with high percentage of blood lymphocytes before the start of treatment, as well as the number of cases of early‑ stage LC, indicates a more significant change in the state of lymphocytes compared to that observed only in LC, as well as the possibility of acceleration of the transition of precancerous cells into malignant process in the lungs under the influence of a previous coronavirus infection.
IMPLEMENTASI PEMBELAJARAN BERDIFERENSIASI DENGAN PENDEKATAN TEACHING AT THE RIGHT LEVEL DALAM PEMBELAJARAN MEMAKNAI INFORMASI TEKS BERITA KELAS VII SMPN 2 PAKIS
Authors: Ananda Dea , Adi Pidekso 
Published: December 2024

Pembelajaran berdiferensiasi dengan pendekatan Teaching at the Right Level (TaRL) adalah salah satu pendekatan pembelajaran yang disusun sebagai upaya untuk mengakomodasi perbedaan antar peserta didik sebagai individu dalam satu kelas agar tidak timbul kesenjangan yang signifikan antar peserta didik dan tercipta pembelajaran yang inklusif, responsif, dan mendukung kebutuhan semua peserta didik. Berdasarkan hasil observasi karakteristik peserta didik kelas VII-C SMPN 2 Pakis, diketahui bahwa tingkat capaian peserta didik kelas VII-C beragam khususnya dalam mata pelajaran Bahasa Indonesia. Oleh karena itu, penelitian ini bertujuan untuk mendeskripsikan langkah-langkah implementasi pembelajaran berdiferensiasi dengan pendekatan Teaching at the Right Level dalam pembelajaran memaknai informasi teks berita di kelas VII-C sebagai upaya menciptakan pembelajaran yang sesuai dengan tingkat capaian peserta didik. Metode yang digunakan penelitian ini adalah kualitatif deskriptif dengan triangulasi data sebagai teknik pengumpulan datanya. Hasil penelitian menunjukkan bahwa tingkat capaian peserta didik di kelas VII-C dipetakan menjadi tiga kelompok, tujuh siswa sangat mahir, sepuluh siswa mahir, dan tiga belas siswa perlu bimbingan. Berdasarkan hasil pemetaan tersebut dirancang pembelajaran diferensiasi TaRL dengan strategi diferensiasi konten dan proses dengan hasil penilaian pengerjaan tugas yang diberikan, hanya ada satu kelompok yang mendapat nilai dibawah 75 (KKM sekolah) dan itu dari kelompok peserta didik mahir.
EFEKTIVITAS MODEL PEMBELAJARAN FLIPPED CLASSROOM PADA MATERI FLUIDA STATIS UNTUK MENINGKATKAN KETERAMPILAN PEMECAHAN MASALAH SISWA KELAS XI
Authors: Saharani Savilla Nadya , Khusaini Khusaini , Sulur Sulur 
Published: December 2024

Penelitian ini bertujuaniuntuk mengetahui peningkatan keterampilan pemecahan masalah siswa karena penerapan model pembelajaran Flipped Classroom. Penelitian ini dilakukan di MAN Kota Batu menggunakan penelitian kuantitatif dengan desain The One Group Pretest Posttest Design. Jumlah sampel pada penelitian ini sebanyak 35 siswa dari kelas XI MIPA 1. Instrumen yang digunakan berupa tes menggunakan google formulir. Berdasarkan hasil analisis uji paired sample t-test dengan taraf siginfikansi 5% didapatkan sebesar 6,45 > 2,03 sehingga ditolak atau terdapat perbedaan yang signifikan dari keterampilan pemecahan masalah siswa sebelum dan setelah pembelajaran, dan peningkatan keterampilan pemecahan masalah sebesar 35%. Dengan demikian dapat disimpulkan bahwa model pembelajaran Flipped Classroom dapatimeningkatkan keterampilan pemecahan masalah siswa dan peningkatan keterampilan pemecahan masalah siswa setelah diberi perlakuan berada dalam kategori sedang. Penelitian berikutnya diharapkan dapat menemukan aplikasi yang lebih baik untuk melakukan e-assessment.
Pengaruh Sistem Zonasi Terhadap Prestasi Belajar Ditinjau Dari Kualitas Input Peserta Didik di SMP Negeri 2 Jogoroto Kabupaten Jombang
Authors: Sari Dwi Kumala , Sunandar Asep , Gunawan Imam , Timan Agus 
Published: December 2024

Abstract: The zoning system is a policy for admitting prospective new students by using the radius closest to the school. This study aims to (1) find out how high the quality level of input is student, (2) find out how high the level of student learning achievement, (3) determine whether or not the zoning system has significant influence on learning achievement in terms of the quality input of student, (4) knowing whether or not there is a difference in thevalue input and student achievement in zoning and non-zoning systems. This study uses a quantitative approach with simple and comparative linear regression methods using data in the form of report cards and national examination scores. The conclusions of this study are: (1) there is a significant difference between the quality of input of students of the 2018/2019 class and the 2016/2017 class, (2) there is no significant difference between the learning achievement of students of the 2018/2019 class and the 2016/2017 class. (3) there is no influence of the zoning system on student achievement in terms of the quality input of studentin SMP Negeri 2 Jogoroto, Jombang Regency, (4) there is a difference in the sample mean of the two pairs ofquality input, but there is no difference in the average sample. on two pairs of learning achievement.
Abstrak: Sistem zonasi merupakan kebijakan dalam penerimaan calon peserta didik baru dengan menggunakan radius jarak terdekat dengan sekolah. Penelitian ini bertujuan untuk (1) mengetahui seberapa tinggi tingkat kualitas input peserta didik, (2) mengetahui seberapa tinggi tingkat prestasi belajar peserta didik, (3) mengetahui ada atau tidaknya pengaruh yang signifikan sistem zonasi terhadap prestasi belajar ditinjau dari kualitas input peserta didik, (4) mengetahui ada atau tidak perbedaan nilai input dan prestasi belajar peserta didik pada sistem zonasi dan non zonasi. penelitian ini menggunakan metode pendekatan kuantitatif dengan metode regresi linier sederhana dan komparatif yang menggunakan data berupa nilai rapor dan nilai UN. Kesimpulan penelitian ini yaitu: (1) terdapat perbedaan yang signifikan antara kualitas input peserta didik angkatan 2018/2019 dengan angkatan 2016/2017, (2) tidak terdapat perbedaan yang signifikan antara prestasi belajar peserta didik angkatan 2018/2019 dengan angkatan 2016/2017, (3) tidak adanya pengaruh sistem zonasi terhadap prestasi belajar peserta didik ditinjau dari kualitas input peserta didik di SMP Negeri 2 Jogoroto Kabupaten Jombang, (4) terdapat perbedaan rata-rata sampel pada dua pasangan kualitas input, namun tidak terdapat perbedaan rata-rata sampel pada dua pasangan prestasi belajar.
Peningkatan Hasil Belajar Matematika Materi FPB dan KPK Menggunakan Media “DASI” (Dakon Multifungsi) pada Siswa Kelas V SDN Gadang 3 Kota Malang
Authors: Fikriyah Samrotul , Hakim Arief Rahman , Setiawan Dwi Agus , Kusumawati Dina Ari , Lestari Tri 
Published: December 2024

Abstract: This research aims to describe the improvement in learning outcomes using the "DASI" (Dakon Multifunction) media in mathematics learning on FPB and KPK material for class V students at SDN Gadang 3, Malang City. This research uses the Kemmis & MC model of Classroom Action Research. Taggart. The research subjects were 32 class V students at SDN Gadang 3, Malang City. Data collection techniques use observation, tests and documentation. The research results show that learning mathematics using the "DASI" (Dakon Multifunction) media can improve student learning outcomes in FPB and KPK material. Student learning outcomes increased, namely from 32 students the percentage of completeness of learning outcomes in the pre-cycle was 16%, in the cycle it became 38%, in the second cycle it became 56%, and in the third cycle it became 78%. The average value of student learning outcomes also increased from pre-cycle of 34.6, cycle I to 55, cycle II to 75, and cycle III to 84.4. So it can be concluded that the use of "DASI" (Dakon Multifunction) media can improve mathematics learning outcomes for FPB and KPK material in class V students at SDN Gadang 3, Malang City.
Abstrak: Penelitian ini bertujuan untuk mendeskripsikan peningkatan hasil belajar menggunakan media “DASI” (Dakon Multifungsi) pada pembelajaran matematika materi FPB dan KPK pada siswa kelas V SDN Gadang 3 Kota Malang. Penelitian ini menggunakan jenis Penelitian Tindakan Kelas model Kemmis & MC. Taggart. Subjek penelitian yakni siswa kelas V SDN Gadang 3 Kota malang berjumlah 32 siswa. Teknik pengumpulan data menggunakan observasi, tes, dan dokumentasi. Hasil penelitian menunjukkan pembelajaran matematika menggunakan media “DASI” (Dakon Multifungsi) dapat meningkatkan hasil belajar siswa pada materi FPB dan KPK. Hasil belajar siswa meningkat yaitu dari 32 siswa persentase ketuntasan hasil belajar pada pra siklus adalah sebesar 16%, pada siklus menjadi 38%, siklus II menjadi 56%, dan siklus III menjadi 78%. Nilai rata-rata hasil belajar siswa juga meningkat dari pra siklus sebesar 34,6, siklus I menjadi 55, siklus II menjadi 75, dan siklus III menjadi 84,4. Sehingga dapat disimpulkan bahwa penggunaan media “DASI” (Dakon Multifungsi) dapat meningkatkan hasil belajar matematika materi FPB dan KPK pada siswa kelas V SDN Gadang 3 Kota Malang.