bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electrophysical properties of the (SnSe)1−x–(SmSe)x solid solutions at high and low temperature
Authors: Abdurahmanova V. A. , Abdullaev N. M. , Ismayilov Sh. S. 
Published: December 2019

The temperature range of [Formula: see text] = 77–770 K in the system alloys: Holl coefficient [Formula: see text], thermo-emf [Formula: see text], electric conductivity [Formula: see text], measured [Formula: see text]-density of components and analyzed. It has been established that samarium additive atoms contain donor-type properties and the effectiveness increases with the temperature increase: up to 40% proportional to [Formula: see text] K in [Formula: see text]-type specimens, whereas in [Formula: see text]-type samples this increase is higher and covers the contents of pH varying from [Formula: see text] to [Formula: see text]. An electrical conductivity of compounds increased due to the carrier activation with further increase of temperature. The activation energy of carriers at low temperatures ([Formula: see text] K) is [Formula: see text] eV for [Formula: see text] mol.% and [Formula: see text] mol.% compounds at [Formula: see text] = 77–320 K and for [Formula: see text] mol.% and [Formula: see text] mol.% compounds are [Formula: see text] eV. [Formula: see text] const at [Formula: see text]–400 K for [Formula: see text] mol.% and [Formula: see text] mol.% compounds, and passing with minimum increases at [Formula: see text] = 400–500 K.
Influence of multi-sintering on the thermoelectric properties of Bi2Sr2Co2Oy ceramics
Authors: Zhang Y. , Fan M. M. , Ruan C. C. , Zhang Y. W. , Li X.-J. , Song H. Z. 
Published: December 2019

[Formula: see text] ceramic samples have a structure similar to phonon glass electronic crystals, and their thermoelectric properties can be effectively adjusted through repeated grinding and sintering. The results show that multi-sintering can make their grain refined and increase their grain boundary, which will effectively increase density and phonon scattering. Finally, multi-sintering can reduce the resistivity and thermal conductivity, thus obviously improve thermoelectric figure of merit [Formula: see text] of [Formula: see text]. The optimum [Formula: see text] value of 0.26 is achieved at 923 K by the third sintered sample.
Performance: Música em Movimento
Authors: Palermo Filho Silas da Luz 
Published: December 2019

A música é uma atividade; e como tal, exige-se o fazer humano. A despeito das abstrações teóricas, ela não é simplesmente algo conceitual, mas pensamento em ação. Música somente se dá a partir do movimento de pessoas imbuídas no processo do fazer, do performar. O objetivo do presente trabalho é abordar a origem do pensamento idealista ocidental em música e como este influenciou todo o desenvolvimento musical gerando uma hierarquização entre teoria e práxis, valorizando mais um em detrimento de outro, resultando em reducionismo no significado do fazer música, antes de se pensar no significado da música em si, mas da música para nós. O conceito de Obra musical apegada somente a notação musical e seu autor sem considerar o intérprete e sua contribuição ativa, não apenas reativa, é restrito e idealizado. Contrapomos o pensamento de Platão, Aristóteles, Pitágoras, Boécio, entre outros, com o de Sexto Empírico, como pensadores precursores no ocidente; o neoplatonismo da era cristã, e ainda musicólogos modernos que se defrontaram sobre questões estéticas da música. Entendemos que o fazer-música é cerne da existência dela, a música.
Dysphagia Screening for Pneumonia Prevention in a Cancer Hospital: Results of a Quality/Safety Initiative
Authors: Ebersole Barbara , Lango Miriam , Ridge John , Handorf Elizabeth , Farma Jeffrey , Clark Sarah , Jamal Nausheen 
Published: December 2019

ObjectiveHospital‐acquired aspiration pneumonia remains a rare but potentially devastating problem. The best means by which to prevent aspiration in a cancer hospital population has not been evaluated. The aim of this study was to evaluate the impact of dysphagia screening on aspiration pneumonia rates in an acute care oncology hospital.MethodsA prospective single‐institution quality improvement dysphagia screening protocol at a comprehensive cancer center. Effect of dysphagia screening implemented in 2016 on hospital‐acquired aspiration pneumonia rates coded “aspiration pneumonitis due to food/vomitus” was compared with rates from 2014 to 2015 prior to implementation. Screening compliance, screening outcomes, patient demographics, and medical data were reviewed as part of a post hoc analysis.ResultsOf 12,392 admissions in 2014 to 2016, 97 patients developed aspiration pneumonia during their hospitalization. No significant change in aspiration pneumonia rate was seen during the dysphagia screening year when compared to prior years (baseline, 7.36; screening year, 8.78 per 1000 discharges; P =. 33). Sixty‐eight of the cases (66%) were associated with emesis/gastrointestinal obstruction or perioperative aspiration and only 15 (15%) with oropharyngeal dysphagia. Multivariate analysis found that patients admitted to gastrointestinal surgery had an aspiration risk equivalent to patients admitted to head and neck, thoracic, and pulmonary services (odds ratio, 0.65; P =. 2).DiscussionNursing‐initiated dysphagia screening did not decrease aspiration pneumonia rates. The causes of aspiration‐associated pneumonia were heterogeneous. Aspiration of intestinal contents is a more common source of hospital‐acquired pneumonia than oropharyngeal dysphagia.
The effectiveness of the Internet-based self-management program for cancer-related fatigue patients: a systematic review and meta-analysis
Authors: Huang Junting , Han Yang , Wei Jiejie , Liu Xiaobo , Du Yanying , Yang Linqing , Li Ying , Yao Wanxia , Wang Ruijun 
Published: December 2019

Objective: To systematically investigate how fatigue, depression, anxiety, sleep quality, and life quality are influenced by the Internet-based self-management program (IBSMP) among cancer patients. Data sources: Eight databases (Cochrane Library, Ovid, Web of Science, Medline, Embase, Chinese biomedical database (CBM), China National Knowledge Infrastructure (CNKI), and Wanfang) were systematically searched from inception to January 2019. Methods: The aim of this study is to identify randomized controlled trials (RCTs) associated with the IBSMP among cancer-related fatigue (CRF) patients. Two reviewers independently screened 1128 records and selected 13 articles, including 1603 patients for inclusion. The quality of the evidence was assessed at the study level and at the outcome level. Results: The meta-analysis showed that the IBSMP was effective for ameliorating fatigue and related symptoms among cancer survivors (the Brief Fatigue Index, relative risk = 0.74, 95% confidence interval (CI; 0.69, 0.79), P < 0.01; the Cancer Fatigue Scale or the Multidimension Fatigue Scale, weighted mean difference = −10.15, 95% CI (−11.42, −8.89), P < 0.01; the Self-rating Anxiety scale, relative risk = 1.07, 95% CI (0.55, 2.05), P < 0.01; the Self-rating Depression scale, relative risk = 0.70, 95% CI (0.60, 0.81), P < 0.01; the Pittsburgh Sleep Quality Index, relative risk = 0.46, 95% CI (0.33, 0.62), P < 0.01; and the Function Assessment of Cancer Therapy—General scale or the Function Assessment of Cancer Therapy—Breast, weighted mean difference = 13.76, 95% CI (3.38, 24.14), P < 0.01.) Conclusion: This meta-analysis demonstrates that the IBSMP, as one of the rehabilitation forms, can reduce the incidence of fatigue, depression, and anxiety and improve sleep quality and life quality among CRF patients.
Morphological Assessment of MACI Grafts in Patients with Revision Surgery and Total Joint Arthroplasty
Authors: Beck Aswin , Wood David , Vertullo Christopher J. , Ebert Jay , Janes Greg , Sullivan Martin , Zheng Ming-Hao 
Published: December 2019

Objective To compare the histological and immunohistochemical characteristics of matrix-assisted chondrocyte implantation (MACI) grafts between patients with revision surgery and patients with total joint arthroplasty. Methods Biopsies of MACI grafts from patients with revision and total joint arthroplasty. The graft tissue characteristics and subchondral bone were examined by qualitative histology, ICRS (International Cartilage Repair Society) II scoring and semiquantitative immunohistochemistry using antibodies specific to type I and type II collagen. Results A total of 31 biopsies were available, 10 undergoing total knee arthroplasty (TKA) and 21 patients undergoing revision surgery. Patients in the clinically failed group were significantly older (46.3 years) than patients in the revision group (36.6 years) ( P = 0.007). Histologically, the predominant tissue in both groups was of fibrocartilaginous nature, although a higher percentage of specimens in the revision group contained a hyaline-like repair tissue. The percentages of type I collagen (52.9% and 61.0%) and type II collagen (66.3% and 42.2%) were not significantly different between clinically failed and revised MACI, respectively. The talar dome contained the best and patella the worst repair tissue. Subchondral bone pathology was present in all clinically failed patients and consisted of bone marrow lesions, including edema, necrosis and fibrosis, intralesional osteophyte formation, subchondral bone plate elevation, intralesional osteophyte formation, subchondral bone cyst formation, or combinations thereof. Conclusions MACI grafts in patients with revision and total joint arthroplasty were predominantly fibrocartilage in repair type, did not differ in composition and were histologically dissimilar to healthy cartilage. Clinically failed cases showed evidence of osteochondral unit failure, rather than merely cartilage repair tissue failure. The role of the subchondral bone in relation to pain and failure and the pathogenesis warrants further investigation.
Overexpression of TCP8 delays Arabidopsis flowering through a FLOWERING LOCUS C-dependent pathway
Authors: Wang Xiaoyan , Xu Xintong , Mo Xiaowei , Zhong Luyao , Zhang Jiancong , Mo Beixin , Kuai Benke 
Published: December 2019

AbstractBackgroundFlowering is a key process in the life cycle of plants. The transition from vegetative to reproductive growth is thus under sophisticated regulation by endogenous and environmental signals. The plant-specific Teosinte Branched 1/Cycloidea/Proliferating Cell Factors (TCP) family transcription factors are involved in many biological processes, but their roles in regulating flowering have not been totally elucidated.ResultsWe explored the role of ArabidopsisTCP8in plant development and, especially, in flowering control. Overexpression ofTCP8significantly delayed flowering under both long-day and short-day conditions and dominant repression byTCP8led to various growth defects. The upregulation ofTCP8led to more accumulated mRNA level ofFLOWERING LOCUS C(FLC), a central floral repressor of Arabidopsis.TCP8functions in an FLC-dependent manner, asTCP8overexpression in theflc-6loss-of-function mutant failed to delay flowering. The vernalization treatment could reverse the late flowering phenotype caused byTCP8overexpression.ConclusionsOur results provide evidence for a role ofTCP8in flowering control and add to our knowledge of the molecular basis ofTCP8function.
Graft failure of IgA nephropathy in renal allografts following living donor transplantation: predictive factor analysis of 102 biopsies
Authors: Zhang Jin , Chen Guo-dong , Qiu Jiang , Liu Guo-chang , Chen Li-zhong , Fu Kai , Wu Zi-xuan 
Published: December 2019

AbstractBackgroundTo investigate predictive factors related to graft failure of IgA nephropathy(IgAN) in renal allografts following living donor transplantation.MethodsWe identified a series of 102 biopsies diagnosed as IgAN in renal allografts following living donor transplantation from July 2004 to January 2017 at our center, and assess the predict value of the Lee’s classification and the 2009 Oxford classification in IgAN in renal allografts, clinical, ultrasonic and pathological characteristics at biopsy and the outcomes were retrospectively analyzed.ResultsThe 5-year graft cumulative survival rate after transplantation was 91.4%. The 4-year graft cumulative survival rate after biopsy diagnosis of IgAN in renal allografts was 59.6%. The mean time ± SD to disease was 4.7 ± 3.5 years. The color doppler ultrasound and blood flow imagine showed the echo enhancement, the reduced blood flow distribution, the reduced peak systolic velocity of main renal artery, and the increased resistance index of arcuate renal artery were valuable in evaluating the graft dysfunction. The Cox multivariate analysis revealed that the 24-h urinary protein level (HR 1.6 for 1-g increase, 95%CI 1.2–2.0), estimated glomerular filtration rate (eGFR) (HR 1.0 for 1-mL/min/1.73 m^2 decline, 95%CI 1.0–1.1), and mesangial C1q deposition (HR 3.0, 95%CI 1.2–7.4) at biopsy were independent predictive factors of graft failure of IgAN in renal allografts.ConclusionsIgAN in renal allografts occurred frequently within 5 years after transplantation. The risk of graft failure should be taken seriously in patients who exhibit heavy proteinuria and/or a declined eGFR as the initial symptoms; a high lesion grade (grade IV-V of Lee’s classification) and/or mesangial C1q deposition may also indicated a poor outcome.
Why acute ischemic stroke patients in the United States use or do not use emergency medical services transport? Findings of an inpatient survey
Authors: Xirasagar Sudha , Tsai Meng-han , Heidari Khosrow , Hardin James W. , Wu Yuqi , Wronski Robert , Hurley Dana , Jauch Edward C. , Sen Souvik 
Published: December 2019

Abstract
Background
Patients with acute ischemic stroke (AIS) who use emergency medical services (EMS) receive quicker reperfusion treatment which, in turn, mitigates post-stroke disability. However, nationally only 59% use EMS. We examined why AIS patients use or do not use EMS.

Methods
During 2016–2018, a convenience sample of AIS patients admitted to a primary stroke center in South Carolina were surveyed during hospitalization if they were medically fit, available for survey when contacted, and consented to participate. The survey was programed into EpiInfo with skip patterns to minimize survey burden and self-administered on a touchscreen computer. Survey questions covered symptom characteristics, knowledge of stroke and EMS importance, subjective reactions, role of bystanders and financial factors. Descriptive and multiple regression analyses were performed.

Results
Of 108 inpatients surveyed (out of 1179 AIS admissions), 49% were male, 44% African American, mean age 63.5 years, 59% mild strokes, 75 (69%) arrived by EMS, 33% were unaware of any stroke symptom prior to stroke, and 75% were unaware of the importance of EMS use for good outcome. Significant factors that influenced EMS use decisions (identified by regression analysis adjusting for stroke severity) were: prior familiarity with stroke (self or family/friend with stroke) adjusted odds ratio, 5.0 (95% confidence interval, 1.6, 15.1), perceiving symptoms as relevant for self and indicating possible stroke, 26.3 (7.6, 91.1), and bystander discouragement to call 911, 0.1 (0.01,0.7). Further, all 27 patients who knew the importance of EMS had used EMS. All patients whose physician office advised actions other than calling EMS at symptom onset, did not use EMS.

Conclusion
Systematic stroke education of patients with stroke-relevant comorbidities and life-style risk factors, and public health educational programs may increase EMS use and mitigate post-stroke disability.
Does HOTAIR expression level in the peripheral blood have veritably predictive/prognostic impact on breast cancer patients?
Authors: Ezzatizadeh Vahid , Mozdarani Hossein 
Published: December 2019

AbstractAs a peripheral blood biomarker, the crucial role of long non-coding RNA (lncRNA) HOTAIR has recently been suggested in many types of disorder. Among these reports, few investigations have indicated overexpression of HOTAIR transcript in the breast cancer patients’ peripheral blood. In this regard, we studied the potential impact of radiotherapy on the peripheral blood HOTAIR expression of different breast cancer patients. Curiously, no significant expression level of HOTAIR was determined in the breast cancer patients’ peripheral blood, before and after radiotherapy (10 Gy exposure). Deliberating these investigations raised some debates on the specificity of the utilized methods, the corresponding obtained findings and impact of HOTAIR expression on breast cancer predication, as a potential peripheral blood biomarker, which is discussed in this article.
Beneficial effects of xenon inhalation on behavioral changes in a valproic acid-induced model of autism in rats
Authors: Dobrovolsky A. P. , Gedzun V. R. , Bogin V. I. , Ma D. , Ichim T. E. , Sukhanova Iu. A. , Malyshev A. V. , Dubynin V. A. 
Published: December 2019

AbstractBackgroundXenon (Xe) is a noble gas that has been used for the last several decades as an anesthetic during surgery. Its antagonistic effect on glutamate subtype of NMDA (N-methyl-d-aspartate) receptors resulted in evaluation of this gas for treatment of CNS pathologies, including psychoemotional disorders. The aim of this study was to assess the behavioral effects of acute inhalation of subanesthetic concentrations of Xe and to study the outcomes of Xe exposure in valproic acid (VPA)-induced rodent model of autism.MethodsWe have conducted two series of experiments with a battery of behavioral tests aimed to evaluate locomotion, anxiety- and depression-like behavior, and social behavior in healthy, VPA-treated and Xe-exposed young rats.ResultsWe have shown that in healthy animals Xe exposure resulted in acute and delayed decrease of exploratory motivation, partial decrease in risk-taking and depressive-like behavior as well as improved sensorimotor integration during the negative geotaxis test. Acute inhalations of Xe in VPA-exposed animals led to improvement in social behavior, decrease in exploratory motivation, and normalization of behavior in forced-swim test.ConclusionBehavioral modulatory effects of Xe are probably related to its generalized action on excitatory/inhibitory balance within the CNS. Our data suggest that subanesthetic short-term exposures to Xe have beneficial effect on several behavioral modalities and deserves further investigation.
HDAC2 hyperexpression alters hippocampal neuronal transcription and microglial activity in neuroinflammation-induced cognitive dysfunction
Authors: Sun Xiao-Yu , Zheng Teng , Yang Xiu , Liu Le , Gao Shen-Shen , Xu Han-Bing , Song Yu-Tong , Tong Kun , Yang Li , Gao Ya , Wu Tong , Hao Jing-Ru , Lu Chen , Ma Tao , Gao Can 
Published: December 2019

Abstract
Background
Inflammation can induce cognitive dysfunction in patients who undergo surgery. Previous studies have demonstrated that both acute peripheral inflammation and anaesthetic insults, especially isoflurane (ISO), are risk factors for memory impairment. Few studies are currently investigating the role of ISO under acute peri-inflammatory conditions, and it is difficult to predict whether ISO can aggravate inflammation-induced cognitive deficits. HDACs, which are essential for learning, participate in the deacetylation of lysine residues and the regulation of gene transcription. However, the cell-specific mechanism of HDACs in inflammation-induced cognitive impairment remains unknown.

Methods
Three-month-old C57BL/6 mice were treated with single versus combined exposure to LPS injected intraperitoneally (i.p.) to simulate acute abdominal inflammation and isoflurane to investigate the role of anaesthesia and acute peripheral inflammation in cognitive impairment. Behavioural tests, Western blotting, ELISA, immunofluorescence, qRT-PCR, and ChIP assays were performed to detect memory, the expressions of inflammatory cytokines, HDAC2, BDNF, c-Fos, acetyl-H3, microglial activity, Bdnf mRNA, c-fos mRNA, and Bdnf and c-fos transcription in the hippocampus.

Results
LPS, but not isoflurane, induced neuroinflammation-induced memory impairment and reduced histone acetylation by upregulating histone deacetylase 2 (HDAC2) in dorsal hippocampal CaMKII+ neurons. The hyperexpression of HDAC2 in neurons was mediated by the activation of microglia. The decreased level of histone acetylation suppressed the transcription of Bdnf and c-fos and the expressions of BDNF and c-Fos, which subsequently impaired memory. The adeno-associated virus ShHdac2, which suppresses Hdac2 after injection into the dorsal hippocampus, reversed microglial activation, hippocampal glutamatergic BDNF and c-Fos expressions, and memory deficits.

Conclusions
Reversing HDAC2 in hippocampal CaMKII+ neurons exert a neuroprotective effect against neuroinflammation-induced memory deficits.
Early and intermediate outcomes for surgical management of infective endocarditis
Authors: Volk Lindsay , Verghis Nina , Chiricolo Antonio , Ikegami Hirohisa , Lee Leonard Y. , Lemaire Anthony 
Published: December 2019

Abstract
Objective
The treatment of active infective endocarditis (IE) presents a clinical dilemma with uncertain outcomes. This study sets out to determine the early and intermediate outcomes of patients treated surgically for active IE at an academic medical center.

Methods
A retrospective chart review was conducted to identify patients who underwent surgical intervention for IE at our institution from July 1st, 2011 to June 30th, 2018. In-patient records were examined to determine etiology of disease, surgical intervention type, postoperative complications, length of stay (LOS), 30-day in-hospital mortality, and 1-year survival.

Results
Twenty-five patients underwent surgical intervention for active IE. The average age of the patients was 47 ± 14 years old and most of the patients were male (N = 15). The majority of the patients had the mitral valve replaced (N = 10), with the remaining patients having tricuspid (N = 8) and aortic (N = 7) valve replacements. The etiology varied and included intravenous drug use (IVDU), and presence of transvenous catheters. The 30-day in-hospital mortality was 4% with 1 patient death and the 1-year survival was 80%. The average LOS was 27 days ±15 and the longest LOS was 65 days.

Conclusions
Surgical management of IE can be difficult and challenging however mortality can be minimized with acceptable morbidity. The most common complication was CVA. The average LOS is longer than traditional adult cardiac surgery procedures and the recurrence rate of valvular infection is not minimal especially if the underlying etiology is IVDU.