bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nomenclatural anomalies among Kunth's Rubiaceae
Authors: Kirkbride Joseph H. , Wiersema John H. 
Published: February 2020

AbstractHumboldt and Bonpland made one of the most important early expeditions yielding plant collections from Latin America. Carl Sigismund Kunth prepared the Nova genera et species plantarum for their magnificent Voyage aux régions équinoctiales du Nouveau Continent, fait en 1799–1804. At almost the same time, Roemer and Schultes were publishing the 16th edition of Linnaeus's Systema vegetabilium. Many Latin American species were treated in both publications under different names. In most cases, Kunth's names have priority over those published in Roemer and Schultes, but there are exceptions. Six rubiaceous names of Kunth are illegitimate because he cited prior valid names as synonyms: Declieuxia chiococcoides, Hedyotis cervantesii, Hedyotis hypnoides, Spermacoce distans, Spermacoce diversifolia (≡ Crusea simplex, comb. nov.), and Spermacoce tenella, and one, Macrocnemum tinctorium, because it is a later homonym. Many botanists have treated these names as available or improperly typified them; all are illegitimate and not to be used, and their typification is resolved.
UV constraints on massive spinning particles: lessons from the gravitino
Authors: Melville Scott , Roest Diederik , Stefanyszyn David 
Published: February 2020

Abstract
Self-interacting massive particles with spin ≥ 1 unavoidably violate unitarity; the question is at what scale. For spin-1 the strong coupling scale (at which perturbative unitarity is lost) cannot be raised by any finite tuning of the interactions, while for spin-2 there exists a special tuning of the Wilson coefficients which can raise this scale (and enjoys numerous special properties such as ghost-freedom). Here, we fill in the missing piece by describing how the self-interactions of a massive spin-3/2 field, or “massive gravitino”, become strongly coupled at high energies. We show that while several different structures appear in the leading order potential, the strong coupling scale cannot be raised (in the absence of additional fields). At the level of the off-shell Lagrangian, it is always the non- linear symmetries of the longitudinal Stückelberg mode that dictate the strong coupling, and we show that in general it is only possible to parametrically raise the strong coupling scale if Wess-Zumino structures exist for these symmetries. We complement this off-shell approach with a first analysis of positivity bounds for a massive spin-3/2 particle, showing that any potential self-interaction which contributes to an on-shell 2-to-2 elastic process at tree level must vanish if this low-energy theory is to have a standard UV completion. We identify the mixing between the longitudinal mode and the transverse modes as the main obstacle to positivity, and clarify how the non-Abelian nature of non-linear (dRGT) massive gravity allows it to satisfy positivity where all known spin ≥ 3/2 Abelian theories fail. Our results imply that a massive gravitino cannot appear alone in a controlled EFT — it must be accompanied by other particles, e.g. as part of a supermultiplet. Together with the spin-1 and spin-2 cases, we suggest features which will persist in even higher spin massive theories.
Gauge-invariant spectral description of the U (1) Higgs model from local composite operators
Authors: Dudal D. , van Egmond D.M. , Guimarães M.S. , Holanda O. , Palhares L.F. , Peruzzo G. , Sorella S.P. 
Published: February 2020

Abstract
The spectral properties of a set of local gauge-invariant composite operators are investigated in the U(1) Higgs model quantized in the ’t Hooft Rξ gauge. These operators enable us to give a gauge-invariant description of the spectrum of the theory, thereby surpassing certain incommodities when using the standard elementary fields. The corresponding two-point correlation functions are evaluated at one-loop order and their spectral functions are obtained explicitly. As expected, the above mentioned correlation functions are independent from the gauge parameter ξ, while exhibiting positive spectral densities as well as gauge-invariant pole masses corresponding to the massive photon and Higgs physical excitations.
Analytical amplitudes from numerical solutions of the scattering equations
Authors: De Laurentis Giuseppe 
Published: February 2020

Abstract
The CHY formalism for massless scattering provides a cohesive framework for the computation of scattering amplitudes in a variety of theories. It is especially compelling because it elucidates existing relations among theories which are seemingly unrelated in a standard Lagrangian formulation. However, it entails operations that are highly non-trivial to perform analytically, most notably solving the scattering equations. We present a new Python package (seampy1) to solve the scattering equations and to compute scattering amplitudes. Both operations are done numerically with high-precision floating-point algebra. Elimination theory is used to obtain solutions to the scattering equations for arbitrary kinematics. These solutions are then applied to a variety of CHY integrands to obtain tree amplitudes for the following theories: Yang-Mills, Einstein gravity, biadjoint scalar, Born-Infeld, non-linear sigma model, Galileon, conformal gravity and (DF)2. Finally, we exploit this high-precision numerical implementation to explore the singularity structure of the amplitudes and to reconstruct analytical expressions which make manifest their pole structure. Some of the expressions for conformal gravity and the (DF)2 gauge theory are new to the best of our knowledge.
Baseline SD-OCT characteristics of diabetic macular oedema patterns can predict morphological features and timing of recurrence in patients treated with dexamethasone intravitreal implants
Authors: Eandi Chiara M. , De Geronimo Daniele , Giannini Daniela , Polito Maria Sole , Tosi Gian Marco , Neri Giovanni , Le Mer Yannick , Varano Monica , Parravano Mariacristina 
Published: February 2020

Abstract
Aims
To evaluate the timing and spectral-domain optical coherence tomography (SD-OCT) features of diabetic macular oedema (DME) recurrence according to baseline OCT patterns in patients treated with dexamethasone implant (DEX-I).

Methods
This is a retrospective observational study (72 eyes/65 patients). Best-corrected visual acuity, timing of DME recurrence, and SD-OCT pattern [intraretinal cysts (IRC), IRC plus subretinal fluid (mixed), external limiting membrane (ELM), ellipsoid (IS/OS) layer integrity] were assessed at baseline and monthly until first DME recurrence.

Results
Forty-two (58.3%) and 30 (41.6%) DME eyes had an IRC and mixed DME pattern at baseline, respectively. Twenty-four out of thirty mixed eyes (80%) relapsed without subretinal fluid. At baseline, mixed eyes showed similar changes in ELM and IS/OS (60 and 76.6% of eyes, respectively) versus IRC eyes (42.8 and 80.9% of eyes). After DME recurrence, more mixed eyes at baseline showed ELM and IS/OS changes (63.3 and 86.6%) than IRC eyes (50 and 76.2%). 33.3% of mixed eyes had DME recurrence at ≥ 6 months from first DEX-I implant versus 19% of IRC eyes.

Conclusions
Mixed DME eyes were treated with DEX-I relapse later and more frequently without subretinal fluid than IRC eyes. SD-OCT characteristics of different DME patterns at baseline can predict morphological features and timing of DME recurrence.
d-Amino acids and kidney diseases
Authors: Kimura Tomonori , Hesaka Atsushi , Isaka Yoshitaka 
Published: February 2020

Abstractd-Amino acids are the recently detected enantiomers of l-amino acids. Accumulating evidence points their potential in solving the long-standing critical problems associated with the management of both chronic and acute kidney diseases. This includes estimating kidney function, early diagnosis and prognosis of chronic kidney disease, and disease monitoring. Among the d-amino acids, d-serine levels in the blood are strongly correlated with the glomerular filtration rate and are useful for estimating the function of the kidney. Urinary d-serine also reflects other conditions. The kidney proximal tubule reabsorbs serine with chiral-selectivity, with d-serine being reabsorbed much less efficiently than l-serine, and urinary excretion of d-serine is sensitive to the presence of kidney diseases. Therefore, assessing the intra-body dynamics of d-serine by measuring its level in blood and urinary excretion can be used to detect kidney diseases and assess pathophysiology. This new concept, the intra-body dynamics of d-serine, can be useful in the comprehensive management of kidney disease.
Hot-Band Anti-Stokes Fluorescence Properties of Alexa Fluor 568
Authors: Gajdos Tamás , Hopp Béla , Erdélyi Miklós 
Published: February 2020

AbstractHot-band absorption and anti-Stokes emission properties of an organic fluorescent dye, Alexa Fluor 568, were characterized and compared with those of Rhodamine 101. The comparison of the properties (e.g., quantum efficiency, spectral distribution, thermal properties, and fluorescence lifetime) between the two dyes confirms that both dyes undergo the same process when excited in the red spectral region. Possible undesirable crosstalk effects and applications in dSTORM microscopy were demonstrated and discussed.
The Predictive Value of Return to Work Self-efficacy for Return to Work Among Employees with Cancer Undergoing Chemotherapy
Authors: Rosbjerg Rikke , Hansen Dorte Gilså , Zachariae Robert , Hoejris Inger , Lund Thomas , Labriola Merete 
Published: February 2020

AbstractPurpose The aim of the present study was to examine the predictive value of Return to Work Self-efficacy (RTWSE) on Return to Work (RTW) among employees undergoing chemotherapy for cancer and to examine the relative contribution of RTWSE as predictor variable compared to personal, health-related, illness- and treatment-related and work-related factors. Methods A sample of 114 sickness absent employees with various cancers (age 18–62) included in the study on average 33 days after initiating chemotherapy were followed for 15 months. Data sources included patient questionnaires (RTWSE, depression, fatigue, performance status), sociodemographic factors (age, sex, job type, and perceived support from the workplace), patient records (type of cancer, treatment intention, number of treatment modalities, time since diagnosis and time since initiation of chemotherapy), and Danish national registries (RTW and education). Associations between RTWSE at baseline and weeks until full RTW during 15-months follow-up were analyzed using Cox proportional hazards regression. Results In the univariate analysis, high RTWSE was associated with shorter time to RTW (Hazard Ratio (HR) 1.84, 95% confidence interval (CI) 1.12–3.03). In the multivariate model, RTWSE failed to reach statistical significance (HR 1.12, 95% CI 0.62–2.02), whereas female sex (HR 0.30, 95% CI 0.15–0.60) and receiving palliative treatment (HR 0.15, 95% CI 0.05–0.44) were significantly associated with later RTW. Conclusion Compared to other factors of significance, RTWSE was not the strongest predictor of RTW when examined among employees undergoing chemotherapy for cancer. Before using the RTWSE questionnaire to identify employees with cancer at risk of late RTW, it is important to recognize that the predictive value of RTWSE may be different for employees on sick leave due to cancer than for other sickness absence populations.
Combined use of refraction seismic, MASW, and ambient noise array measurements to determine the near-surface velocity structure in the Selinunte Archaeological Park, SW Sicily
Authors: Schwellenbach Iris , Hinzen Klaus-G. , Petersen Gesa Maria , Bottari Carla 
Published: February 2020

AbstractSeismic refraction, multichannel analysis of surface waves (MASW) and ambient noise array measurements using the wireless array analysis (WARAN) system were applied to acquire near-surface profiles of seismic velocities in the Selinunte Archaeological Park. This ancient city is famous for numerous temples, which according to the literature, were destroyed by at least two earthquakes in antiquity. The morphology of the archeological park is affected by two rivers which in combination with the temple remains suggests three study sites. We determined the subsurface velocity at these three locations as essential information for further studies of the response of the temple structures to earthquake ground motions. The stratigraphy of the site indicates that low-velocity layers might exist. Seismic refraction profiles with 69 m spread and 24 geophones were employed during the active seismic experiments. The measured P-wave velocities of the top two layers were used as a constraint during the inversion of dispersion relations from the MASW and WARAN data. The reliability of the velocity profiles was tested by forward calculation of synthetic seismograms. P-wave velocities which were not well constraint throughout the dispersion curve inversions were adjusted through suitable Poisson’s ratios based on the well constraint S-velocities. The combined use of the three different kinds of measurements and multi-mode interpretation of the dispersion curves revealed velocity profiles including low-velocity layers which are supported by de-amplification observed in ratios of horizontal and vertical components of noise spectra.
Excitation dynamics in Photosystem I trapped in TiO2 mesopores
Authors: Szewczyk S. , Białek R. , Giera W. , Burdziński G. , van Grondelle R. , Gibasiewicz K. 
Published: February 2020

AbstractExcitation decay in closed Photosystem I (PSI) isolated from cyanobacterium Synechocystis sp. PCC 6803 and dissolved in a buffer solution occurs predominantly with a ~ 24-ps lifetime, as measured both by time-resolved fluorescence and transient absorption. The same PSI particles deposited in mesoporous matrix made of TiO2 nanoparticles exhibit significantly accelerated excitation decay dominated by a ~ 6-ps component. Target analysis indicates that this acceleration is caused by ~ 50% increase of the rate constant of bulk Chls excitation quenching. As an effect of this increase, as much as ~ 70% of bulk Chls excitation is quenched before the establishment of equilibrium with the red Chls. Accelerated quenching may be caused by increased excitation trapping by the reaction center and/or quenching properties of the TiO2 surface directly interacting with PSI Chls. Also properties of the PSI red Chls are affected by the deposition in the TiO2 matrix: they become deeper traps due to an increase of their number and their oscillator strength is significantly reduced. These effects should be taken into account when constructing solar cells’ photoelectrodes composed of PSI and artificial matrices.
On discernibility in symmetric languages: the case of quantum particles
Authors: Bigaj Tomasz 
Published: February 2020

AbstractIn this paper I consider the question of whether absolute discernibility is attainable in symmetric languages. Simon Saunders has proven that all facts expressible in first-order language with identity can be equivalently stated within its symmetric sublanguage. I use this result to show specifically how particles of the same type can be absolutely discerned in the permutation-invariant language of the quantum theory of many particles.
Metabolic characterisation of THP-1 macrophage polarisation using LC–MS-based metabolite profiling
Authors: Abuawad Alaa , Mbadugha Chidimma , Ghaemmaghami Amir M. , Kim Dong-Hyun 
Published: February 2020

AbstractIntroductionMacrophages constitute a heterogeneous population of functionally distinct cells involved in several physiological and pathological processes. They display remarkable plasticity by changing their phenotype and function in response to environmental cues representing a spectrum of different functional phenotypes. The so-called M1 and M2 macrophages are often considered as representative of pro- and anti-inflammatory ends of such spectrum. Metabolomics approach is a powerful tool providing important chemical information about the cellular phenotype of living systems, and the changes in their metabolic pathways in response to various perturbations.ObjectivesThis study aimed to characterise M1 and M2 phenotypes in THP-1 macrophages in order to identify characteristic metabolites of each polarisation state.MethodsHerein, untargeted liquid chromatography (LC)–mass spectrometry (MS)-based metabolite profiling was applied to characterise the metabolic profile of M1-like and M2-like THP-1 macrophages.ResultsThe results showed that M1 and M2 macrophages have distinct metabolic profiles. Sphingolipid and pyrimidine metabolism was significantly changed in M1 macrophages whereas arginine, proline, alanine, aspartate and glutamate metabolism was significantly altered in M2 macrophages.ConclusionThis study represents successful application of LC–MS metabolomics approach to characterise M1 and M2 macrophages providing functional readouts that show unique metabolic signature for each phenotype. These data could contribute to a better understanding of M1 and M2 functional properties and could pave the way for developing new therapeutics targeting different immune diseases.
Increased autophagy/mitophagy levels in primary tumours of patients with pancreatic neuroendocrine neoplasms
Authors: Daskalakis Kosmas , Alexandraki Krystallenia I. , Kloukina Ismini , Kassi Evanthia , Felekouras Evangelos , Xingi Evangelia , Pagakis Stamatis N. , Tsolakis Apostolos V. , Andreakos Evangelos , Kaltsas Gregory , Kambas Konstantinos 
Published: February 2020

Abstract
Background/aims
We assessed the levels of autophagy and mitophagy, that are linked to cancer development and drug resistance, in well differentiated pancreatic neuroendocrine neoplasms (PanNENs) and correlated them with clinico-pathological parameters.

Methods
Fluorescent immunostaining for the autophagy markers LC3Β and p62/or LAMP1 was performed on 22 PanNENs and 11 controls of normal pancreatic tissues and validated through Western blotting. Autophagy quantitative scoring was generated for LC3B-positive puncta and analysed in relation to clinico-pathological parameters. TOMM20/LC3B qualitative assessment of mitophagy levels was undertaken by fluorescent immunostaining. The presence of autophagy/mitophagy was validated by transmission electron microscopy.

Results
Autophagy levels (LC3B-positive puncta/cell) were discriminative for normal vs. NEN pancreatic tissue (p = 0.007). A significant association was observed between autophagy levels and tumour grade (Ki67 < 3% vs. Ki67 ≥ 3%; p = 0.021), but not functionality (p = 0.266) size (cut-off of 20 mm; p = 0.808), local invasion (p = 0.481), lymph node- (p = 0.849) and distant metastases (p = 0.699). Qualitative assessment of TOMM20/LC3B demonstrated strong mitophagy levels in PanNENs by fluorescent immunostaining as compared with normal tissue. Transmission electron microscopy revealed enhanced autophagy and mitophagy in PanNEN tissue. Response to molecular targeted therapies in metastatic cases (n = 4) did not reveal any patterns of association to autophagy levels.

Conclusions
Increased autophagy levels are present in primary tumours of patients with PanNENs and are partially attributed to upregulated mitophagy. Grade was the only clinico-pathological parameter associated with autophagy scores.
Moving the prevention timeline: A scoping review of the literature on precursors to sexual risk in early adolescence among youth of color
Authors: Tuitt Nicole R. , Asdigian Nancy L. , Whitesell Nancy Rumbaugh , Mousseau Alicia , Al‐Tayyib Alia , Kaufman Carol E. 
Published: February 2020

ABSTRACTIntroductionSexual health disparities are leading causes of morbidity among youth of color in the United States. We conducted a scoping review of the literature on precursors to sexual risk‐taking among young adolescents of color (ages 10–14) to assess precedents of sexual experience and their utility as measurable proximal constructs and behaviors gauging sexual risk and sexual risk prevention efforts.MethodsThis study was conducted using the PRISMA extension for scoping reviews (PRISMA‐ScR) guidelines. We searched for quantitative studies that assessed the relationships between precursors and subsequent sexual behaviors, incorporated youth of color, and specified young adolescents as the study sample. All articles were in English, however we explored both U.S. and International databases.ResultsThe database search yielded 11 studies published between 2000 and 2017. Most literature focused on youth in urban settings, and on Black and Latinx youth, while only two addressed the special circumstances of American Indian and Alaska Native youth. Sex expectancies outcomes for youth of color were likely to predict sexual risk taking and self‐efficacy about sex was related to abstinence.ConclusionsEtiologic studies that seek to understand precursors to sexual risk taking among youth of color are limited and this paucity truncates the ability to develop sexual risk prevention programs for the age group in which prevention is most needed.
Dependence of Sudden Stratospheric Warmings on Internal and External Drivers
Authors: Salminen A. , Asikainen T. , Maliniemi V. , Mursula K. 
Published: February 2020

AbstractA sudden stratospheric warming (SSW) is a large‐scale disturbance of the wintertime stratosphere, which occurs especially in the Northern Hemisphere. Earlier studies have shown that SSW occurrence depends on atmospheric internal factors and on solar activity. We examine SSW occurrence in northern winters 1957/1958–2016/2017, considering several factors that may affect the SSW occurrence: Quasi‐Biennial Oscillation (QBO), El Niño–Southern Oscillation (ENSO), geomagnetic activity, and solar radiation. We confirm the well‐known result that SSWs occur more often in easterly QBO phase than in westerly phase. We show that this difference depends on how the QBO phase is determined. We find that the difference in SSW occurrence between easterly and westerly QBO winters strengthens (weakens) if geomagnetic activity or solar activity is low (high), or if the ENSO is in a cold (warm) phase. In easterly QBO phase significantly more SSWs occur during low geomagnetic activity than high activity.
High‐Order Solar Migrating Tides Quench at SSW Onsets
Authors: He Maosheng , Forbes Jeffrey M. , Chau Jorge L. , Li Guozhu , Wan Weixing , Korotyshkin Dmitry V. 
Published: February 2020

AbstractSudden stratospheric warming events (SSWs) are the most spectacular atmospheric vertical coupling processes, well‐known for being associated with diverse wave activities in the upper atmosphere and ionosphere. The first four solar tidal harmonics have been reported as being engaged. Here, combining mesospheric winds detected by three midlatitude radars, we demonstrate at least the first six harmonics that occurred during SSW 2018. Wave number diagnosis demonstrates that all six harmonics are dominated by migrating components. Wavelet analyses reveal that the fourth, fifth, and sixth harmonics quench after the SSW onset. The six harmonics and the quenching appear also in a statistical analysis based on near‐12‐year observations from one of the radars. We attribute the quenching to reversal of the background eastward wind.