bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary Incidence of Autoimmune Tyroiditis in the Republic of Belarus and Radiation Factor
Authors: Rozhko V. , Veyalkin I. , Sharshakova T. 
Published: April 2020

Actuality: In the Belarus, the primary incidence of thyroid pathology is in the 2d rank among endocrine diseases after diabetes. Studying the trends in the primary incidence of autoimmune thyroiditis (AIT) in the Belarus is important for improving organizational decisions and further improving the quality of medical care for the population.
Purpose: Is to conduct a comparative analysis of the incidence of AIT in the population and in the affected population based on an epidemiological study in the Belarus, taking into account the radiation and organizational components in the formation of pathology.
Material and methods: The data of the republican statistical reports and the data of the Chernobyl Register from 1997 to 2017 were analyzed. Standard methods of descriptive epidemiology were used in the work.
Results: According to Chernobyl Registry, during the observation period (1997–2017), the primary incidence of AIT decreased by 1.4 times (1997 – 135.1 ± 15.77 0/0000; 2017 – 98.4 ± 7.55 0/0000). The incidence was statistically significantly higher in women than men (ratios ranged from 2.39: 1 in 2004 to 4.0: 1 in 2000). Moreover, the incidence according to Chernobyl Registry was higher than in the adult population, but in children where was no difference with population data. This indicates a high-quality clinical examination of the children’s population. Two organizational and medical approaches have been formed in the republic. The first approach (Grodno, Brest, Minsk regions and Minsk) is characterized by periods of moderate growth, decline, and growth again. In the second approach (Vitebsk, Mogilev and Gomel regions), there are two periods when the increase in incidence sharply changes to decrease before the end of the study period. An analysis of the odds ratio allowed us to conclude that insignificant effect of radioactive iodine on the incidence of AIT in children at the time of the accident and its absence in the adult population.
Conclusion: The study confirms the importance of the organizational component in the early diagnosis of AIT.
Molecular Imaging of Neuroendocrine Tumors by Somatostatin-Receptor Scintigraphy (SPECT/CT) with 99mTc-Tektrotyd
Authors: Slashchuk K. , Rumyantsev P. , Degtyarev M. , Serzhenko S. , Baranova O. , Trukhin A. , Sirota Ya. 
Published: April 2020

Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms constituting about 0.5 % of all cancer cases. In recent years, there has been a significant increase in the incidence of NETs, which is primarily due to the active development and improvement of medical imaging technologies. Successful treatment and prognosis for patients with NETs strongly depend on the stage of the disease. One of the effective methods of visualization and staging NETs in nuclear medicine is somatostin receptor scintigraphy (SRS), which is based on the use of partial somatostatin receptor agonists labeled with radioactive isotopes. The article presents an analysis of 55 patients with NETs of various localizations who underwent scintigraphy and SPECT/CT. Radiopharmaceutical was used as a tracer for SRS. It was prepared on the basis of a lyophilisate developed by Polatom (Poland) — Tektrotyd, labeled with 99mTc. According to the results of the study SRS with 99mTc-Tektrotyd is informative in the topical diagnosis of NETs, especially when PET/CT scan with 68Ga-labeled peptides is not available. Sensitivity varies depending on the NET localization. It is necessary to continue researches on the diagnostic value of SRS with 99mTc-Tektrotyd for tumors, in the pathogenesis of which somatostatin receptors play a significant role.
Synergistic interaction of education, science, and industry
Authors: Klimuk Vladimir , Tarasova Anna , Yulia Kuznetsova , Laura Dzhabrailova 
Published: April 2020

AbstractEconomic and social development of a country rely on advanced science and technology, skilled, educated workforce, extensive growth of innovation and population density. The process of innovation creation can be long and winding and should take into account the needs of technological development and definitely bring benefits to business. The concept of a science park has not been new. The United States of America were pioneers who in early 1950s suggested a brand new model for bridging the gap between academia and industry. Nowadays developed countries employ that model, though its objectives, funds, inputs and outcomes may vary. This paper will focus of the issue of real interaction of institutions of education, science and industry and will raise a number of controversial issues in the correction of the vector for socio-economic modernization. The authors analyzed a set of legislation acts on regulating the cooperation of academia and business. The paper gives a graphical model of reciprocity of institutions of education, science, and industry taking into account the interests of public authorities, and offers a set of additional indicators of evaluation of the efficiency of functioning of an innovation structure in the country (region).
As Escolas Médicas e os desafios da formação médica diante da epidemia brasileira da COVID-19: das (in)certezas acadêmicas ao compromisso social.
Authors: De Oliveira Sandro Schreiber , Postal Eduardo Arquimino , Afonso Denise Herdy 
Published: April 2020

A epidemia de Covid-19 no Brasil já se constitui uma das mais impactantes questões de saúde pública na realidade do País e no mundo moderno, em decorrência das múltiplas consequências e tensões que atingem a nossa sociedade. Ainda que o foco esteja na proteção aos usuários e à comunidade, o cenário de epidemia no Brasil interferiu de forma abrupta no processo educacional da formação médica e de outros cursos da saúde, exigindo um remodelamento emergencial e demandando atenção e diálogo ágil entre educadores, gestores e sociedade.
A preocupação com o impacto da epidemia na formação dos futuros médicos, está presente ao redor do mundo(1), com ênfase no desafio de adequação do processo formativo ao cenário de epidemia, em função da não integralização das cargas horárias preconizadas, do deslocamento das atividades previstas para alguns campos de prática diversos, da possibilidade e antecipação das formaturas e do uso adicional de tecnologias educacionais à distância, que podem impactar a execução do projeto pedagógico original dos cursos, bem como das próprias diretrizes curriculares nacionais.
Kajian Penerapan Simbiosis Industri Pada Rantai Pasok Otomotif
Authors: Masjud Yunita Ismail 
Published: April 2020

Pendekatan symbiosis industri merupakan salah satu pendekatan yang dapat dilakukan terhadap pengelolaan lingkungan industri. Pengelolaan lingkungan industry menjadi penting mengingat industry merupak sector yang paling besar berkontribusi terhadap Pendapatan Regional Bruto (PDB) dan juga menyerap tenaga kerja cukup besar. Pembentukan symbiosis industry membutuhkan sinergi dan kolaborasi pada awal pembentukannya. Sinergi dan kolaborasi terjadi di rantai pasok, termasuk rantai pasok otomotif. Penelitian ini bertujuan melihat pengaruh sinergi dan kolaborasi terhadap terjadinya pertukaran materi, pertukaran energi, pertukaran produk samping dan pertukaran air. Penelitian ini dilakukan terhadap perusahaan komponen otomotif yang berlokasi di Jabodetabek, yang merupakan suplayer PT Astra Daihatsu Motor (PT.ADM) dan memprodukdi komponen yang masa pakainya singkat (fast moving). Sampel dipilih secara purposive dan pengumpulan data menggunakan koesioner yang didistribusikan secara online. Data yang terkumpul dianalisis dengan menggunakan model regresi berganda dengan variable independent adalah sinergi dan kolaborasi, sedangkan variable dependen adalah pertukaran materi, pertukaran energi, pertukaran produk samping dan pertukaran air. Hasil yang diperoleh menunjukkan bahwa sinergi berpengaruh signifikan terhadap perubahan materi dan pertukaran air. Kolaborasi berpengaruhi signifikan terhadap pertukaran produk samping dan pertukaran energi tidak dipengaruhi secara signifikan oleh sinergi dan kolaborasi.
PENGARUH LATIHAN YOGA TERHADAP KADAR GLUKOSA DARAH PUASA PADA WANITA DEWASA AWAL
Authors: Lady Chantika , Dieny Fillah Fithra , Probosari Enny 
Published: April 2020

Latar Belakang : Lebih dari 90% penderita diabetes mellitus berstatus gizi obesitas. Olahraga yang tepat dilakukan dan direkomendasikan oleh American Diabetes Association dalam mengontrol kadar glukosa darah dan profil lipid adalah olahraga dengan intensitas sedang, seperti yoga. Penelitian ini bertujuan untuk mengetahui pengaruh latihan yoga terhadap kadar glukosa darah puasa (GDP) pada wanita dengan kelebihan berat badan. Metode: Penelitian quasi experiment dengan rancangan pre-post test with control group design sebanyak 22 subjek dan dipilih dengan menggunakan metode consecutive sampling, dibagi menjadi 2 kelompok dengan metode simple randomization. Subjek penelitian adalah 22 wanita usia 19-25 tahun yang dibagi menjadi 2 kelompok, yaitu kelompok perlakuan mendapat latihan yoga 60 menit sebanyak 10 kali selama 20 hari dan edukasi gizi, dan kelompok kontrol hanya mendapatkan edukasi gizi. Data glukosa darah puasa diukur 2 kali yaitu sebelum dan sesudah penelitian dengan alat spektofotometri dengan metode Glucocard TM Test Strip; sedangkan data asupan makanan diambil sebanyak 5 kali selama intervensi berlangsung dengan menggunakan metode Food Recall. Data dianalisis dengan uji Wilcoxon, Uji Mann Whitney, dan regresi linier untuk variable perancu selama intervensi. Hasil : Terdapat penurunan nilai Glukosa Darah Puasa yang bermakna (p = 0,01) pada kelompok perlakuan dengan nilai GDP dari 113,64 mg/dl ± 55,24 menjadi 102 mg/dl ± 52,69. Pada kelompok kontrol ada penurunan GDP namun tidak bermakna (p = 0,18) yaitu 117,73 mg/dl ± 60,32 menjadi 110,73 mg/dl ± 65,47. Berdasarkan selisih penurunan GDP antara kelompok perlakuan lebih besar (11,63 mg/dl ± 11,77) dibanding kelompok kontrol (7,00 mg/dl ± 17,07).Namun selisih GDP pada kedua kelompok setelah intervensi latihan yoga tidak bermakna (p = 0,18). Kesimpulan : Latihan yoga selama 10 kali pada wanita obesitas tidak signifikan berpengaruh terhadap penurunan kadar glukosa darah puasa.
PERBEDAAN KADAR ASAM URAT PADA WANITA LANSIA DENGAN PERSEN LEMAK TUBUH OBESITAS DAN NON-OBESITAS
Authors: Andarbeni Larasati , Probosari Enny 
Published: April 2020

Latar Belakang : Obesitas adalah suatu kelainan metabolisme, dimana terjadi ketidakseimbangan antara energi yang masuk dan energi yang keluar. Obesitas pada lansia merupakan salah satu masalah kesehatan paling serius didunia. Pada penderita obesitas, resiko untuk mengalami penyakit gout lebih tinggi. Penyakit gout lebih sering menyerang pada orang yang mengalami kelebihan berat badan lebih dari 30%. Penelitian ini bertujuan untuk mengetahui perbedaan kadar asam urat pada wanita lansia obesitas dan non obesitas.Metode :Jenis penelitian ini adalah observasional dengan rancangan cross-sectional. Jumlah subjek penelitian adalah 56 orang wanita dengan usia 60-74 tahun. Kadar asam urat diperoleh menggunakan metode enzimatik, sedangkan status obesitas diperoleh menggunakan alat BIA (Bioelectrical Impedance Analyser).Hasil :Kadar asam urat sebagian besar kadar asam urat subjek (78,6%) berada dalam rentang normal, yaitu antara 2,6 – 6 mg/dl, sementara 12 orang subjek (21,4%) mengalami hiperurisemia. Pada subjek obesitas ditemukan 7 orang subjek hiperurisemia (> 6mg/dl), sedangkan pada subjek non obesitas ditemukan 5 orang subjek hiperurisemia ( 6mg/dl). Hasil statistik menunjukkan bahwa tidak terdapat perbedaan kadar asam urat antara subjek obesitas dan non obesitas (p>0,05).
Challenges to Athletes During the Home Confinement Caused by the COVID-19 Pandemic
Authors: Andreato Leonardo V. , Coimbra Danilo R. , Andrade Alexandro 
Published: April 2020

ABSTRACT
The world is currently facing a serious coronavirus pandemic (COVID-19). This novel coronavirus is a new virus for which effective drugs and vaccines have not yet been developed. Amateur and professional athletic events around the world have been stopped, and teams and athletes have had to adopt social withdrawal measures, interrupting their training and preparation routines for competitions. Given this alarming scenario, this article aims to alert athletes to the importance of maintaining a conditioning routine during this confinement period.
Peripheral Nerve Single-Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth
Authors: Toma Jeremy S. , Karamboulas Konstantina , Carr Matthew J. , Kolaj Adelaida , Yuzwa Scott A. , Mahmud Neemat , Storer Mekayla A. , Kaplan David R. , Miller Freda D. 
Published: April 2020

AbstractPeripheral nerves provide a supportive growth environment for developing and regenerating axons and are essential for maintenance and repair of many non-neural tissues. This capacity has largely been ascribed to paracrine factors secreted by nerve-resident Schwann cells. Here, we used single-cell transcriptional profiling to identify ligands made by different injured rodent nerve cell types and have combined this with cell-surface mass spectrometry to computationally model potential paracrine interactions with peripheral neurons. These analyses show that peripheral nerves make many ligands predicted to act on peripheral and CNS neurons, including known and previously uncharacterized ligands. While Schwann cells are an important ligand source within injured nerves, more than half of the predicted ligands are made by nerve-resident mesenchymal cells, including the endoneurial cells most closely associated with peripheral axons. At least three of these mesenchymal ligands, ANGPT1, CCL11, and VEGFC, promote growth when locally applied on sympathetic axons. These data therefore identify an unexpected paracrine role for nerve mesenchymal cells and suggest that multiple cell types contribute to creating a highly pro-growth environment for peripheral axons.
The notion of state. Connotations of topical usage using discourse analysis
Authors: Kažoka Aija 
Published: April 2020

One of the most powerful political concepts in Europe, including Latvia, is the welfare state. Whether or not the Latvian language environment reveals hopes and expectations regarding the notion may be determined through a close study of the parliamentary discourse of the past five years, as well as the language user opinions regarding state. The goal of the research is to analyse the topical usage of the notion state and its connotations. As data collection tools, the study used language corpora which display the most frequent collocations and the related semantic fields of a given word. The data analysis was carried out via critical discourse analysis focusing on the dominant characteristics in the language use. The analysis found contradictory usage of the word state. Within the speeches of the members of the parliament, deviations from the definition of the state and new connotations attached to the notion were observed, implying a collective responsibility of the state instead of individual. Both language users and members of the parliament await a strict governmental management and wish to view it as an authority. The desire of a wealth-providing, generous state could signify a hope for a welfare state, albeit peculiarly interpreted.
Twelve tips for rapidly migrating to online learning during the COVID-19 pandemic
Authors: Sandars John , Correia Raquel , Dankbaar Mary , de Jong Peter , Goh Poh Sun , Hege Inga , Masters Ken , Oh So-Young , Patel Rakesh , Premkumar Kalyani , Webb Alexandra , Pusic Martin 
Published: April 2020

This article was migrated. The article was marked as recommended. The COVID-19 pandemic has resulted in a massive adaptation in health professions education, with a shift from in-person learning activities to a sudden heavy reliance on internet-mediated education. Some health professions schools will have already had considerable educational technology and cultural infrastructure in place, making such a shift more of a different emphasis in provision. For others, this shift will have been a considerable dislocation for both educators and learners in the provision of education. To aid educators make this shift effectively, this 12 Tips article presents a compendium of key principles and practical recommendations that apply to the modalities that make up online learning. The emphasis is on design features that can be rapidly implemented and optimised for the current pandemic. Where applicable, we have pointed out how these short-term shifts can also be beneficial for the long-term integration of educational technology into the organisations' infrastructure. The need for adaptability on the part of educators and learners is an important over-arching theme. By demonstrating these core values of the health professions school in a time of crisis, the manner in which the shift to online learning is carried out sends its own important message to novice health professionals who are in the process of developing their professional identities as learners and as clinicians.
SeisIO: A Fast, Efficient Geophysical Data Architecture for the Julia Language
Authors: Jones Joshua P. , Okubo Kurama , Clements Tim , Denolle Marine A. 
Published: April 2020

Abstract
SeisIO for the Julia language is a new geophysical data framework that combines the intuitive syntax of a high-level language with performance comparable to FORTRAN or C. Benchmark comparisons against recent versions of popular programs for seismic data download and analysis demonstrate significant improvements in file read speed and orders-of-magnitude improvements in memory overhead. Because the Julia language natively supports parallel computing with an intuitive syntax, we benchmark test parallel download and processing of multiweek segments of contiguous data from two sets of 10 broadband seismic stations, and find that SeisIO outperforms two popular Python-based tools for data downloads. The current capabilities of SeisIO include file read support for several geophysical data formats, online data access using a variety of services, and optimized versions of several common data processing operations. Tutorial notebooks and extensive documentation are available to improve the user experience. As an accessible example of performant scientific computing for the next generation of researchers, SeisIO offers ease of use and rapid learning without sacrificing computational efficiency.
Virtual Fault Ruptures in Area-Source Zones for PSHA: Are They Always Needed?
Authors: Bommer Julian J. , Montaldo Falero Valentina 
Published: April 2020

AbstractSeismic source models for probabilistic seismic hazard analysis (PSHA), except when using zoneless approaches based directly on the earthquake catalog, invariably include area-source zones, even if active fault sources are modeled explicitly. Because most modern ground-motion prediction equations (GMPEs) employ source-to-site distance metrics defined relative to extended fault ruptures rather than to the epicenter or hypocenter, it becomes necessary to generate virtual fault ruptures within the area-source zones to enable calculation of the correct distance of each earthquake scenario from the site of interest. For a site-specific PSHA, the work of defining the virtual rupture characteristics such as strike, dip, and style of faulting, for more distant source zones, and the computational effort of simulating these ruptures for each earthquake scenario in the hazard calculations, may be unnecessary. Beyond a certain distance from the site, it can be demonstrated that the loss of accuracy introduced by modeling the individual earthquake scenarios as point sources rather than as extended ruptures is usually sufficiently small to allow the distance metric in the GMPEs to be treated as epicentral or hypocentral distance. Such simplifications can significantly increase the efficiency of the hazard calculations and also relieve the seismic source modelers of considerable effort to characterize virtual ruptures far beyond the host zone of the site. Treating earthquake scenarios in the more remote source zones as points also brings the additional benefit of avoiding problems that can arise with the largest magnitude scenarios leading to ruptures that approach the site in cases for which the ruptures are not constrained to remain within the source boundaries.
A perspectiva vygotskyana na formação docente online: observações na educação superior
Authors: C. Lima Hallwass Lia 
Published: April 2020

A formação docente torna-se cada vez mais desafiadora no contexto da educação. Em meio a uma sociedade tecnológica, focada em desempenhos e resultados, a formação docente contempla discussões sobre a práxis e o complexo cenário de ensinar, apoiar a aprendizagem e avaliar em meio a tantas metodologias e abordagens psicológicas. Esse mesmo cenário requer qualificação constante, saberes e fazeres docentes e boas práticas. A formação docente precisa encontrar novas possibilidades. O objetivo deste trabalho é analisar as interações sociais entre professores universitários no projeto Sala (Virtual) dos Professores. O projeto foi baseado na perspectiva histórico-cultural de Vygotsky e no potencial das tecnologias, a fim de criar um processo contínuo de interação social e formação docente. Iniciado em 2014, o projeto acontece em um curso de Administração de uma instituição privada do Rio Grande do Sul. Os achados aqui apresentados foram obtidos por meio de observação participante e fichamento das atividades de 28 docentes do curso. Mediante análise temática, os resultados indicam que o projeto contribuiu para: aumentar a participação dos professores nas ações devido à sua flexibilidade espaço-temporal, para a troca de conhecimentos e experiência devido ao atendimento das necessidades específicas dos professores, de suas áreas e disciplinas. Além disso, permitiu estabelecer conexões pessoais, criar estratégias intencionais de forma colaborativa, qualificar as atividades docentes e avaliações, manter uma interação constante, apesar de não ter potencial para substituir a presencialidade necessária para subsidiar a atuação e a formação docente.
Publicaciones, interacciones, verdades y mentiras de adolescentes españoles en Instagram / Posts, interactions, truths and lies of Spanish adolescents on Instagram
Authors: Gil-Quintana Javier , Fernández-Galiano Amoros Manuel 
Published: April 2020

Este estudio indaga acerca de los hábitos de los adolescentes referidos al consumo, producción y creación en Instagram. Se han analizado los tipos de interrelaciones e interacciones que se producen en este espacio y, a su vez, la identidad personal acechada en ocasiones por peligros, verdades y mentiras. La investigación se basa en una metodología mixta, mediante la realización de un cuestionario a 171 adolescentes españoles y el desarrollo de 17 entrevistas grupales a otros 67. Se ha observado que los adolescentes consumen contenido multimedia, sin embargo, no son capaces de crear más allá de las propias interacciones que vienen fagocitadas por Instagram. Sus preferencias de interacción son amistades, influencers o youtubers y familia, con quienes establecen una retroalimentación de stories, likes, directos y otros comentarios. Se ha observado la existencia de peligros, como el acoso, la exclusión y la marginación que llevan al bloqueo de determinados perfiles por su seguridad.