bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two World Systems Collide: Negotiating between Manding and American1 Sensibilities
Authors: Feder Lisa 
Published: July 2020

SummaryWhen jaliya crosses cultural boundaries, distinct differences emerge between Manding and American sensibilities that throw into question whether relating at all is worth the effort. In this article, the author describes three weeks spent in New York where she produces an album for Famoro Dioubaté, a Guinean musician and oral historian called a jali in the Manding language. Historically, jalis render a service to the people in their community through their specialized music and words. In return they receive, sometimes handsome, donations on which they depend for their livelihood. As jalis move to cities like New York and Paris, their habitual ways of doing business do not translate across cultural lines. In this three‐week project, the author uses self‐reflection to describe the assumptions and tensions that mounted around the exchange of money and time. Drawing on their knowledge of both cultural systems, the players involved strive to reach common ground. The following is a detailed account of such interactions.
Reading with robot and human companions in library literacy activities: A comparison study
Authors: Yueh Hsiu‐Ping , Lin Weijane , Wang S‐Chen , Fu Li‐Chen 
Published: July 2020

AbstractMotivated by mixed evidence on the effectiveness of reading companions on children’s reading performance, as well as the clear and present need for libraries to conduct literacy education, this study sought to investigate the feasibility of using social robots in library literacy activities and to extract the essential functions of effective reading companions by comparing human and robot co‐readers. A humanoid robot, Robot Julia, was developed as a social robot to provide oral conversation and offer children tactful and stimulating support for their reading. An experimental study was conducted to examine child patrons’ perceptions and performance in reading activities with the robot companion as compared to human companions. A total of 36 elementary school children participated in the study. The results positively supported that the participants perceived the robot companion as more favourable and desirable to read with than a human co‐reader. The children favoured robotic verbalisation over human verbalisation. According to the results of the comparison, cognitively it was found that human and robot companions facilitated children’s reading comprehension in different ways and that the children performed similarly well with both kinds of reading companions. Affectively, the robot co‐reader induced more social interaction during the reading sessions. Despite all the positive aspects, it is also necessary to consider the limitations including the novelty effect of the approach. This study contributes empirical evidence in the pragmatic field of library science and expands upon social robot research by exploring one‐on‐one child–robot interactions in reading, as opposed to the group contexts in previous studies.
Environmental drivers of femaleness of an inter‐Andean monoecious shrub
Authors: Vélez‐Mora Diego , Ramón Pablo , Vallejo César , Romero Alex , Duncan David , Quintana‐Ascencio Pedro F. 
Published: July 2020

AbstractHetero‐and conspecific interactions, nutrient availability, climate, habitat heterogeneity, and disturbances can generate variation and spatial patterns of femaleness in plants. We assessed whether year, site, plant size, plant density, and canopy area of conspecific neighbors influenced the expression and spatial aggregation of femaleness in Croton aff. wagneri, a monoecious shrub from dry shrublands of the inter‐Andean valleys in Ecuador. We georeferenced in two sites (1,700 and 1,400 m.a.s.l) in five 10 × 10 m plots, within each site, the position of each Croton reproductive plant during first part of flowering season in two years, and measured their height, length, and width. The femaleness index of each plant was determined by the number of female and male buds and flowers. Plant density was determined for each plot, along with the number of neighbors and the summed canopy area of conspecific neighbors (at 1.0, 2.0, and 2.5 m radius, and the five closest plants) from each focal plant. Croton´s femaleness at the lower elevation site was greater than at the higher elevation site and increased with plant size and with canopy of the closest five neighbors. Soil at the lower elevation site had higher temperatures and lower water content. Aggregate patterns of femaleness were found in more plots at the lower elevation site. Our results indicate that location, plant size, and canopies of conspecific neighbors of Croton can affect femaleness and its aggregation and support the hypothesis that femaleness can be influenced by facilitative interactions.Abstract in Spanish is available with online material.
Locoregional control, progression‐free survival and morbidity rates in N3 head and neck cancer patients with low primary tumour burden: A 301‐patient study
Authors: Carsuzaa Florent , Dufour Xavier , Gorphe Philippe , Righini Christian , Cosmidis Alain , Rogé Maximilien , De Mones Erwan , Servagi Vernat Stéphanie , Tonnerre Denis , Morinière Sylvain , Dugas Amaury , Malard Olivier , Pasquier François , Vergez Sébastien , Schick Ulrike , Gérard Michael , Salleron Julia , Thariat Juliette 
Published: July 2020

AbstractObjectivesIn patients with N3 head and neck squamous cell carcinoma (HNSCC), N3 disease is associated with high regional relapse and metastatic risks. Patients with resectable N3 disease have better prognosis although their metastatic risk may be similar as in patients with unresectable disease. Neoadjuvant chemotherapy has been associated with lower metastatic rates, but N3 patients may die of rapid locoregional progression. We assessed outcomes with the three modalities in patients with low primary burden to better assess the specific prognosis of N3 disease.MethodsThis retrospective multicentric study included T0‐2 N3 HNSCC patients. Outcomes and morbidity in upfront neck dissection (uND) vs non‐surgical groups were analysed and oncological outcomes and morbidity compared between patients undergoing chemoradiation or neoadjuvant chemotherapy in patients with initially unresectable N3 nodes.ResultsOf 301 patients, 142 (47%) underwent uND, 68 (23%) neoadjuvant chemotherapy and 91 (30%) chemoradiation. The 24‐ and 60‐month incidence of locoregional relapse was 23.2% [18.3%; 28.4%] and 27.4% [21.8%; 33.3%]; it was lower in patients undergoing uND (P = .006). In patients with non‐surgical treatments, success rates were 57.8% [49.4%; 66.3%] after chemoradiation and 38.1% [29.6%; 46.7%] after neoadjuvant chemotherapy (P = .001). Overall morbidity was more frequent in patients undergoing uND (68.8%) (P < .001).ConclusionuND improved locoregional control but increased morbidity and showed no survival benefit. Success rates were better after chemoradiation versus neoadjuvant chemotherapy. Neoadjuvant chemotherapy did not reduce metastatic rates but non‐responders to chemoradiation had poor PFS and survival rate, suggesting that predictive criteria are warranted.
Where are the bats? An environmental complementarity analysis in a megadiverse country
Authors: Aguiar Ludmilla M. S. , Pereira Maria João R. , Zortéa Marlon , Machado Ricardo B. 
Published: July 2020

AbstractAimField surveys are necessary to overcome Wallacean shortfalls. The task is even more important when human pressure on tropical—megadiverse—ecosystems is considered. However, due to financial constraints, spatial and temporal prioritization is required. Here, we used the concept of environmental complementarity to identify non‐surveyed regions for bats that are environmentally different from other already surveyed regions. We highlighted regions in Brazil where field inventories could be conducted to locate new occurrences or even new bat species.LocationBrazil.MethodsWe based our analysis on environmental characterization aiming to identify dissimilar regions to those already sampled for bats in Brazil. We used 21 environmental variables to characterize 1,531 unique localities where bats occur. Then, we applied the parameters of a generalized linear model (GLM) to extrapolate the expected values of the environmental variables for the entire country. We compared the predicted values of localities with newly described bat species occurrence against the values for other bat species.ResultsWe found that sites from which recently discovered species were described are environmentally distinct from the sites where previously described species occur. Therefore, new occurrences and even new species could be found in regions that are environmentally dissimilar from those already surveyed. By crossing the model with a human footprint map, we defined temporal priorities for field inventories. Regions such as the Northern Cerrado and Western Caatinga should be surveyed first. Similar approaches could be undertaken for other biological groups or regions, allowing the identification of spatial congruence and the development of a comprehensive national programme for biological field inventories.Main conclusionNewly described species occurred in environments dissimilar to those previously identified, showing that environmental complementarity analysis is a valid approach to define priority regions for new bat inventories.
Real‐world evidence of the effectiveness on glycaemic control of early simultaneous versus later sequential initiation of basal insulin and glucagon‐like peptide‐1 receptor agonists
Authors: Rosenstock Julio , Ampudia‐Blasco Francisco Javier , Lubwama Robert , Peng Xuejun Victor , Boss Anders , Shi Lizheng , Fonseca Vivian 
Published: July 2020

AbstractAimTo assess the impact of the timing of initiating both basal insulin and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) on reaching glycaemic control targets over 6 and 12 months in people with type 2 diabetes (T2D) uncontrolled on oral antihyperglycaemic drugs with an HbA1c of 9% or higher.MethodsThis retrospective cohort study assessed the impact of the timing of initiating both basal insulin and GLP‐1 RA therapies on reaching glycaemic targets (HbA1c < 7% and <8%, and ≥1% and ≥2% HbA1c reduction) over 12 months in people with markedly uncontrolled T2D (HbA1c ≥ 9%) on oral antihyperglycaemic drugs identified on the Optum Humedica database (electronic medical records; 1 January 2011 to 30 June 2017). Study cohorts were defined by the days between initiating each injectable: cohort A, 30 days or less (simultaneous initiation) and cohorts B, 31‐90, C, 91‐180, D, 181‐270 and E, 271‐360 days (sequential initiation).ResultsCohort A had the best glycaemic outcomes at 6 and 12 months for all four endpoints, followed by cohort B. The likelihood of achieving an HbA1c of less than 7% did not significantly differ between cohorts A and B (hazard ratio [95% confidence interval]: 0.87 [0.76‐1.01]); cohorts C, D and E were significantly less likely to achieve an HbA1c of less than 7% than cohort A (0.62 [0.53‐0.72]; 0.62 [0.53‐0.72]; 0.63 [0.54‐0.73]).ConclusionsIn people with uncontrolled T2D requiring treatment with a GLP‐1 RA and basal insulin, greater improvements in glycaemic control were observed when both therapies were initiated within close proximity of one another (≤90 days) compared with initiation 91‐360 days apart.
The pervasive and multifaceted influence of biocrusts on water in the world's drylands
Authors: Eldridge David J. , Reed Sasha , Travers Samantha K. , Bowker Matthew A. , Maestre Fernando T. , Ding Jingyi , Havrilla Caroline , Rodriguez‐Caballero Emilio , Barger Nichole , Weber Bettina , Antoninka Anita , Belnap Jayne , Chaudhary Bala , Faist Akasha , Ferrenberg Scott , Huber‐Sannwald Elisabeth , Malam Issa Oumarou , Zhao Yunge 
Published: July 2020

AbstractThe capture and use of water are critically important in drylands, which collectively constitute Earth's largest biome. Drylands will likely experience lower and more unreliable rainfall as climatic conditions change over the next century. Dryland soils support a rich community of microphytic organisms (biocrusts), which are critically important because they regulate the delivery and retention of water. Yet despite their hydrological significance, a global synthesis of their effects on hydrology is lacking. We synthesized 2,997 observations from 109 publications to explore how biocrusts affected five hydrological processes (times to ponding and runoff, early [sorptivity] and final [infiltration] stages of water flow into soil, and the rate or volume of runoff) and two hydrological outcomes (moisture storage, sediment production). We found that increasing biocrust cover reduced the time for water to pond on the surface (−40%) and commence runoff (−33%), and reduced infiltration (−34%) and sediment production (−68%). Greater biocrust cover had no significant effect on sorptivity or runoff rate/amount, but increased moisture storage (+14%). Infiltration declined most (−56%) at fine scales, and moisture storage was greatest (+36%) at large scales. Effects of biocrust type (cyanobacteria, lichen, moss, mixed), soil texture (sand, loam, clay), and climatic zone (arid, semiarid, dry subhumid) were nuanced. Our synthesis provides novel insights into the magnitude, processes, and contexts of biocrust effects in drylands. This information is critical to improve our capacity to manage dwindling dryland water supplies as Earth becomes hotter and drier.
Molecular mechanisms activating the NAIP‐NLRC4 inflammasome: Implications in infectious disease, autoinflammation, and cancer
Authors: Kay Callum , Wang Runli , Kirkby Max , Man Si Ming 
Published: July 2020

AbstractCytosolic innate immune sensing is a cornerstone of innate immunity in mammalian cells and provides a surveillance system for invading pathogens and endogenous danger signals. The NAIP‐NLRC4 inflammasome responds to cytosolic flagellin, and the inner rod and needle proteins of the type 3 secretion system of bacteria. This complex induces caspase‐1‐dependent proteolytic cleavage of the proinflammatory cytokines IL‐1β and IL‐18, and the pore‐forming protein gasdermin D, leading to inflammation and pyroptosis, respectively. Localized responses triggered by the NAIP‐NLRC4 inflammasome are largely protective against bacterial pathogens, owing to several mechanisms, including the release of inflammatory mediators, liberation of concealed intracellular pathogens for killing by other immune mechanisms, activation of apoptotic caspases, caspase‐7, and caspase‐8, and expulsion of an entire infected cell from the mammalian host. In contrast, aberrant activation of the NAIP‐NLRC4 inflammasome caused by de novo gain‐of‐function mutations in the gene encoding NLRC4 can lead to macrophage activation syndrome, neonatal enterocolitis, fetal thrombotic vasculopathy, familial cold autoinflammatory syndrome, and even death. Some of these clinical manifestations could be treated by therapeutics targeting inflammasome‐associated cytokines. In addition, the NAIP‐NLRC4 inflammasome has been implicated in the pathogenesis of colorectal cancer, melanoma, glioma, and breast cancer. However, no consensus has been reached on its function in the development of any cancer types. In this review, we highlight the latest advances in the activation mechanisms and structural assembly of the NAIP‐NLRC4 inflammasome, and the functions of this inflammasome in different cell types. We also describe progress toward understanding the role of the NAIP‐NLRC4 inflammasome in infectious diseases, autoinflammatory diseases, and cancer.
Circular RNA circ_001842 plays an oncogenic role in renal cell carcinoma by disrupting microRNA‐502‐5p‐mediated inhibition of SLC39A14
Authors: Zeng Jiawei , Feng Qian , Wang Yaodong , Xie Gang , Li Yuanmeng , Yang Yuwei , Feng Jiafu 
Published: July 2020

AbstractRenal cell carcinoma (RCC) is a common urologic malignancy, and up to 30% of RCC patients present with locally advanced or metastatic disease at the time of initial diagnosis. Increasing evidence suggests that circular RNAs (circRNAs) serve as genomic regulatory molecules in various human cancers. Our initial in silico microarray‐based analysis identified that circRNA circ_001842 was highly expressed in RCC. Such up‐regulation of circ_001842 in RCC was experimentally validated in tissues and cell lines using RT‐qPCR. Thereafter, we attempted to identify the role of circ_001842 in the pathogenesis of RCC. Through a series of gain‐ and loss‐of function assays, cell biological functions were examined using colony formation assay, Transwell assay, annexin V‐FITC/PI‐labelled flow cytometry and scratch test. A high expression of circ_001842 in tissues was observed as associated with poor prognosis of RCC patients. circ_001842 was found to elevate SLC39A14 expression by binding to miR‐502‐5p, consequently resulting in augmented RCC cell proliferation, migration and invasion, as well as EMT in vitro and tumour growth in vivo. These observations imply the involvement of circ_001842 in RCC pathogenesis through a miR‐502‐5p‐dependent SLC39A14 mechanism, suggesting circ_001842 is a potential target for RCC treatment.
Development and testing of a practicum matching program for baccalaureate nursing education, a local public health unit
Authors: McCullagh Marjorie C. , Mecomber Jennifer , Hubscher Jayne J. , Kingsinger Olivia G. , McBride Kayla M. , Park Soyeon , Souksay Karina J. , Velasquez Chloe Marie V. , Yake Lauren M. 
Published: July 2020

AbstractThis article describes a novel approach to nursing education, designed to improve the experience of both students in public health nursing, and the local public health unit where they affiliate. Students, faculty, and public health department staff developed a method for matching programs and needs of the local public health unit to the skills and learning needs of nursing students. We describe our experience articulating student competencies, program‐specific functions, and an approach to matching student interests and learning opportunities to agency needs. Students, faculty, and staff rated the program moderately to very high in feasibility, satisfaction, and acceptability. Data suggest the novel program served to improve the quality of the practicum affiliation, to the satisfaction of both the school and agency, while contributing to a robust public health learning experience for emerging professional nurses.
Food insecurity as a predictor of metabolic syndrome in U.S. female adults
Authors: Park So‐Hyun , Strauss Shiela M. 
Published: July 2020

AbstractObjectivesTo examine the association between household food insecurity and metabolic syndrome in the U.S. female adult population.DesignWe analyzed the 2007–2014 U.S. National Health and Nutrition Examination Survey data.SampleSample included 4,249 female adults who had complete data on metabolic syndrome components, household food security, and important potential socio‐demographic predictors of metabolic syndrome.MeasurementsHousehold food security was categorized as full, marginal, low, and very low. F‐tests were used to compare those in full food security households and those in each of the other food security category households for prevalence and potential socio‐demographic predictors of metabolic syndrome. Logistic regression analyses were used to determine the association between household food security and metabolic syndrome.ResultsWomen in low food security households were significantly more likely to have a waist circumference ≥88 cm and to have fasting glucose >100 mg/dl. Women in very low food security households were significantly more likely to have high density lipoprotein <50 mg/dl. Women in low and very low food security households were significantly more likely to have triglycerides ≥150 mg/dl.ConclusionsFindings suggest that women in low and very low food security households are at increased risk for metabolic syndrome.
Metrology and sensors as dermo‐cosmetic technology opportunities for a change of paradigm
Authors: Bollinger Caroline , Duong Tu Anh , Genain Gilles , Almaric Nicolas , Moga Alain , Richard William , Vandier Stanislas 
Published: July 2020

AbstractObjectiveMetrology and measures are changing the way patients and consumers behave and help find new, more effective solutions.MethodsThis Review and Prospective Paper identifies applications in the field of dermatology and beauty tech.ResultsThe review of skincare as well as dermatological applications and analysis provides a comprehensive picture of the dynamics in the process of impacting the complete value chain in the field of dermo‐cosmetics, as well as the opportunities offered by a strict approach around new and innovative measures, especially in the field of better patient/consumer knowledge, understanding, and personalized solution offering. It identifies the new business models or opportunities for the cosmetic industry.ConclusionAdapting metrology and measures to skincare is a significant opportunity to change the way things are done today.
Skin-to-skin care alters regional ventilation in stable neonates
Authors: Schinckel Nicholas F , Hickey Leah , Perkins Elizabeth J , Pereira-Fantini Prue M , Koeppenkastrop Sienna , Stafford Isabella , Dowse Georgie , Tingay David G 
Published: July 2020

ObjectiveSkin-to-skin care (SSC) has proven psychological benefits; however, the physiological effects are less clearly defined. Regional ventilation patterns during SSC have not previously been reported. This study aimed to compare regional ventilation indices and other cardiorespiratory parameters during prone SSC with supine and prone position cot-nursing.DesignProspective observational study.SettingSingle quaternary neonatal intensive care unit in Australia.Patients20 infants spontaneously breathing (n=17) or on non-invasive ventilation (n=3), with mean (SD) gestational age at birth of 33 (5) weeks.InterventionsThirty-minute episodes of care in each position: supine cot care, prone SSC and prone cot care preceding a 10 min period of continuous electrical impedance tomography measurements of regional ventilation.Main outcome measuresIn each position, ventral–dorsal and right–left centre of ventilation (CoV), percentage of whole lung ventilation by region and percentage of apparent unventilated lung regions were determined. Heart and respiratory rates, oxygen saturation and axillary temperature were also measured.ResultsHeart and respiratory rates, oxygen saturation, temperature and right-left lung ventilation did not differ between the three positions (mixed-effects model). Ventilation generally favoured the dorsal lung, but the mean (95% CI) ventrodorsal CoV was −2.0 (−0.4 to –3.6)% more dorsal during SSC compared with prone. Supine position resulted in 5.0 (1.5 to 5.3)% and 4.5 (3.9 to 5.1)% less apparently unventilated lung regions compared with SSC and prone, respectively.ConclusionsIn clinically stable infants, SSC generates a distinct regional ventilation pattern that is independent of prone position and results in greater distribution of ventilation towards the dorsal lung.