bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kireç ve perlitle stabilize edilen yüksek plastisiteli kil zeminin geçirimliliği
Authors: ŞADOĞLU Erol , ÇALIK Ümit 
Published: December 2019

Bina,
köprü, yol ve baraj gibi mühendislik yapılarının üzerinde inşa edileceği
zeminler her zaman uygun özelliklerde olmayabilir. Mühendislik yapılarının inşa
edileceği zayıf zeminlerin oluşturduğu ortamlarda
geoteknik mühendisleri, zayıf zemini ıslah etme şeklindeki bir çözümü sıklıkla
tercih eder. Çeşitli katkılarla kimyasal reaksiyonlar yaptırılarak zemin
mühendislik özelliklerinin değiştirilmesine kimyasal stabilizasyon denir. Mekanik stabilizasyon
ile yeterli düzeyde ıslah edilemeyen zeminlere kimyasal stabilizasyon uygulanır.
Kimyasal stabilizasyon zeminin mukavemet, plastisite, kompaksiyon, durabilite
gibi özelliklerinde değişime yol açtığı gibi geçirimlilik özelliğinde de
değişime yol açmaktadır. Zeminlerin geçirimliliği, yeraltı suyu akımı ve sızma
problemlerinde önem arz etmektedir. Fakat, kimyasal stabilizasyonun
geçirimlilik üzerindeki etkisinin araştırıldığı çalışmalar oldukça azdır. Bu
çalışmada, yüksek plastisiteli kil zeminin kireç ve perlit kombinasyonları ile
kimyasal stabilizasyonunun, geçirimlilik üzerindeki etkisi araştırılmıştır. Yüksek plastisiteli kil zeminlerin
kireçle stabilizasyonunda, karışımın geçirimliliğinde 25 kata varan artışlar
meydana gelmektedir. Ayrıca bu tür zeminlerin stabilizasyonunda ikincil katkı
olarak kullanılabilen perlit geçirimlilikte ciddi azalmalara sebep olmaktadır.
Improving the Amplitude Source Location (ASL) Method Using Multicomponent Seismic Data: An Assessment with Active Source Seismic Data
Authors: Walsh Braden , Procter Jonathan , Jolly Arthur 
Published: December 2019

ABSTRACTHere, all three components of the seismic signal are applied for use with the amplitude source location (ASL) method to investigate if using all three components yield more accurate results than using just the vertical component. Eight active source events along a debris flow channel on Te Maari Volcano, New Zealand, are used as known source locations to conduct the test. Both coda-wave normalization (CWN) and horizontal-to-vertical (H/V) ratio methods are used to calculate amplification factors for station corrections. Average location errors for all the active seismic sources varied between 0.47 km for the vertical component and 0.51 km for three components while using the CWN method, and 0.92 km (vertical) and 0.83 km (three component) using the H/V method. We also conduct statistical analysis through an F-test by calculating root mean square errors (RMSEs) to determine if the results were statistically different. The RMSE analysis for the active source events shows location results for event 1 and 7 producing errors of 2.18±1.33 and 2.37±1.29  km for the vertical-component results, and 2.06±1.16 and 2.33±1.24  km for the three-component results. The F-test indicates that active source events higher up the debris flow channel (centrally located relative to the network) are statistically the same, whereas events lower down the channel (away from the center of the network) are statistically different. Results show that using all three components with the ASL method may not necessarily yield more accurate locations, but nevertheless may average the components to eliminate the extreme error values or amplify the signals, producing more precise results.
Bilateral Patellar Stress Fractures in a Skeletally Immature Athlete
Authors: Scully William F. , Rumley MAJ Jacob C. , Caskey Paul M. 
Published: December 2019

Case:This report describes the divergent course and management of bilateral patellar stress fractures in a 17-year-old skeletally immature male athlete. Beginning as bilateral incomplete tension-sided patellar fractures, the right patella healed uneventfully, whereas the left progressed to a complete, mildly displaced transverse fracture that eventually healed with nonoperative treatment measures to include temporary bracing, physical therapy, and vitamin D supplementation.Conclusions:Patellar stress fractures are exceptionally rare, particularly bilateral injuries in the pediatric population. Diligent workup is necessary for appropriate diagnosis, whereas knowledge of the salient features of these injuries is useful in treatment.
Lumbar Disc Herniation Within Solid Fused Segments After Removal of Pedicle Screws
Authors: Ha Kee-Yong , Kim Young-Hoon , Park Hyung-Youl , Min Hyung-Ki , Kim Sang-Il 
Published: December 2019

Case:
A 73-year-old man with instrumented fusion of L3-4-5 underwent the removal of previous pedicle screws and posterior instrumented fusion of L1-2-3. The solid dorsal fusion mass of L3-5 was identified intraoperatively and preoperatively. At 3 years after the second surgery, he presented with abrupt radiating pain in the left leg. Plain radiographs showed a collapse of the intervertebral disc space, and magnetic resonance imaging showed disc herniation of L3-4.

Conclusions:
Disc herniation even in solid fused segments may occur. Removal of pedicle screws and cranial extension of interbody fusion may increase the intradiscal stress associated with physiologic cantilever motion of the disc.
Radiology of Acquired Constriction Band Syndrome: An Unusual Cast Complication
Authors: L.G. Shyamasundar , Madhuri Vrisha 
Published: December 2019

Case:
A severe acquired constriction band in the proximal calf in an infant treated with a below-knee cast, which was protected with a waterproof sheet secured with a rubber band, is described. The radiological and computed tomography features of an elastic band causing the acquired constriction are presented for their novelty and uniqueness in the complication of cast treatment.

Conclusions:
The waterproof covering of plaster casts in children secured with a rubber band to prevent soiling can cause an acquired constriction band, which mimics osteomyelitis. The imaging modalities showed the elastic band shadow cutting through the bone and soft tissues as demonstrated in this case. We recommend that the complication can be prevented by avoiding the use of elastic bands to hold the waterproofing covers for the cast.
Molecular marker assisted gene stacking for disease resistance and quality genes in the dwarf mutant of an elite common wheat cultivar Xiaoyan22
Authors: zheng weijun , Li Song , Liu ZiHui , Zhou Qi , Feng Yanru , Chai ShouCheng 
Published: December 2019

Abstract
Development of wheat cultivars with multiple disease resistance and high quality are major objectives in modern wheat breeding programs. Gene stacking is an efficient approach to achieve this target. In this study, we pyramided yellow rust resistance gene (Yr26), powdery mildew resistance gene (ML91260) and high-molecular-weight glutenin subunits Dx5+Dy10 into the dwarf mutant of an elite wheat cultivar, Xiaoyan22. Six pyramided lines were obtained by molecular marker-assisted selection (MAS) and field evaluation of disease resistance. The desirable agronomic traits of pyramided lines, their identity with the original cultivar Xiaoyan22 except for plant height, tiller number and disease resistance, was achieved in this study. Meanwhile, the yield of pyramided lines is higher than Xiaoyan22 in the field test. In addition, analysis of flour quality indicated that the dough stability time of pyramided lines was longer than that of Xiaoyan22. These results demonstrate that it is feasible to improve multiple agronomic traits simultaneously by rational application of MAS.
Pathogenic fungi-induced susceptibility is mitigated by mutual Lactobacillus plantarum in the Drosophila melanogaster model
Authors: Su Wanzhen , Liu Jialin , Bai Peng , Ma Baocang , Liu Wei 
Published: December 2019

Abstract
Background Since animals frequently encounter a variety of harmful fungi in nature, their ability to develop sophisticated anti-fungal strategies allows them to flourish across the globe. Extensive studies have highlighted the significant involvement of indigenous microbial communities in human health. However, the daunting diversity of mammalian microbiota and host genetic complexity are major obstacles to our understanding of these intricate links between microbiota components, host immune genotype, and disease phenotype. In this study, we sought to develop a bacterium-fungus-Drosophilamodel to systematically evaluate the anti-fungal effects of commensal bacteria. Results We isolated the pathogenic fungal strain, Diaporthe FY, which was detrimental to the survival and development of Drosophilaupon infection. Using Drosophilaas a model system, Drosophila-associatedLactobacillus plantarumfunctioned as a probiotic, and protected the flies from mortality induced by Diaporthe FY. Our results show that L. plantarumhindered the growth of Diaporthe FY in vitro, and decreased the mortality rate of Diaporthe FY-infected flies in vivo, consequently mitigating the toxicity of Diaporthe FY to the hosts. Additionally, the presence of L. plantarumoverrode the avoidance of oviposition on Diaporthe FY-associated substrates. Conclusions Diaporthe FY was identified as a potential Drosophila pathogen. Commensal L. plantarummitigated the susceptibility of Drosophilato pathogenic fungi, providing insight into the natural interplay between commensal and pathogenic microbial communities that contribute to animal health and pathogenesis. Keywords L. plantarum, fungal infection, Drosophila, antagonist, oviposition.
Evaluation of the Safety and Tolerability of a Nutritional Formulation in Patients with Angelman Syndrome (FANS): Study Protocol for a Randomized Controlled Trial
Authors: Herber Donna L. , Weeber Edwin J. , D’Agostino Dominic P. , Duis Jessica 
Published: December 2019

Abstract
Background Ketogenic and low glycemic index diets are effective in treating drug resistant seizures in children with Angelman syndrome. Cognition, mobility, sleep, and gastrointestinal health are intrinsically linked to seizure activity and overall quality of life. Ketogenic and low glycemic diets restrict carbohydrate consumption and stabilize blood glucose levels. The ketogenic diet induces ketosis, a metabolic state where ketone bodies are preferentially used for fuel. The use of exogenous ketones in promoting ketosis in Angelman syndrome has not been previously studied. The study formulation evaluated herein contains the exogenous ketone beta-hydroxybutyrate to rapidly shift the body towards ketosis, resulting in enhanced metabolic efficiency. Methods This is a 16 week, randomized, double blind, placebo-controlled crossover study to assess the safety and tolerability of a nutritional formula containing exogenous ketones. It also examines the potential for exogenous ketones to improve the patient’s nutritional status which can impact the physiologic, symptomatic, and health outcomes liabilities of living with Angelman syndrome. Discussion This manuscript outlines the rationale for a study designed to be the first to provide data on nutritional approaches for patients with Angelman syndrome using exogenous ketones.
Husbands’ experience and perception of supporting their wives during childbirth in Tanzania
Authors: Kashaija Denis Kampayana , Mselle Lilian Teddy , Mkoka Dickson Ally 
Published: December 2019

Abstract

Background: In order improve the quality of birth care and women satisfaction with birthing process it is recommended that every woman should be offered the option to experience labour and childbirth with a companion of her choice. Involving husbands as decision makers in the household may a play role in reducing maternal mortality which is unacceptably high despite the targeted goal to reduce these mortality as targeted in the MDGs by 2015. This is still addressed in the Sustainable Development Goals (SDGs) of 2015/30. This study aimed to explore the experiences and perceptions of husbands’ support of their wives during pregnancy, labour and deliveries in Tanzania.Methods: Qualitative descriptive study design was employed; involving men aged between 24 and 63 years. Participants were selected purposefully at the clinic and in labour ward of SekouToure Regional Referral Hospital (SRRH). The in-depth interview, guided by semi structured interview guide was used to collect the audio recorded and hand written information. Data were analysed using qualitative content analysis Results; Nine (9) semi-structured interviews were conducted with husbands of women attended for antenatal care and those came for deliveries. Four themes emerged; Demonstrating care, love and affection, adopting modern life style, observing women’s right and meeting social economic difficulties. Husbands’ support to their partners is a good behaviour practiced during matrimonial lives. Husbands who support their partners during pregnancy and delivery consider themselves as being modern men as they at home take duties beside their usual tasks to let their wives have adequate time to rest during pregnancy. Poor road infrastructure makes difficult to get transport to the healthcare facility especially when labour is imminent. Also ward infrastructure is not supportive to accommodate husbands when they accompany their wives to the healthcare facility. Conclusions; The healthcare settings in low income countries need to accommodate men during the routine antenatal and intranatal care for the positive outcome of labour and delivery. Exploratory research should be conducted to understand how education and urbanisation affects men involvement in maternal and child health specifically in the low income countries.
A pilot study: A possible implication of Candida as an etiologically endogenous pathogen for oral lichen planus
Authors: He Hong , Xia Xinyu , Yang Haiping , Peng Qiao , Zheng Jiaoer 
Published: December 2019

Abstract
Background: The aim of this study was to investigate the prevalence and genotypic profiles of Candida albicans in patients with oral lichen planus (OLP). Materials and Methods:Positive rates and genotypic profiles of Candida albicansstrains from OLP patients and healthy controls were analyzed. Random amplified polymorphic DNA and internal transcribed spacer of ribosome DNApolymerase chain reactions were used to sequence the DNA of these strains, and then their geneticsimilarity was measured using BLAST, UIV Band, and Vector NTI Suite Sequence AnalysesSoftware. Results:The prevalence of C. albicansstrains detected from erosive-OLP, non-erosive OLP, and normal individuals was 18.87%, 18.75%, and 7.92%, respectively. Four different genotypes were revealed by the two methods. To be specific, type I was found only in the healthy subjects; type II a and II b were found in non-erosive OLP, and type III was identified in erosive OLP. Intragroup similarity coefficients, i.e. SABwere 100%, and inter-groups similarity coefficients, i.e. SABwere less than 30%. Conclusions:The genotypic results of C. albicansin OLP revealed an endogenous rather than exogenous infection of C. albicans. In addition, a possible pathogenic role of C. albicansin OLP, with the etiologic sense contributing to a more proper recognition on the pathogenesis, development, and progression of OLP, as well as some strategies for its diagnosis and treatment were identified.
Epidemiological analysis of the Kaohsiung city strategy for dengue fever quarantine and epidemic prevention
Authors: CHEN Chun-Hong , Pan Chao Ying , Liu Wei-Liang , Su Matthew P. , Chang Te Pin , Ho Hui-Pin , Huang Joh-Jong , Lin Li Jen , Shu Pei-Yun 
Published: December 2019

Abstract
Background. Dengue is endemic in over 100 countries and is an important public health problem worldwide. Dengue is not considered endemic in Taiwan however, with importation of dengue viruses from neighboring countries via close commercial links and air travel believed to be the cause of local outbreaks. Disease control efforts have therefore focused on preventing the importation of dengue into Taiwan. Here, we investigate the relationships between numbers of imported and indigenous dengue cases to test the validity of this strategy. Methods. Dengue-fever case data from between 2013 and 2018 was obtained from the surveillance systems of the Taiwan Center for Disease Control and Kaohsiung City Health department. Standard epidemiological data, including the monthly numbers of indigenous and imported dengue cases, was calculated. Potential associations between the number of indigenous and imported cases were investigated using correlation analyses. Results. We identified a possible relationship between the period of disease concealment and the number of reported imported dengue cases which resulted in indigenous dengue-fever epidemics within local communities. Further analysis of confirmed dengue cases during previous dengue-fever epidemics in Kaohsiung City found that the risk of indigenous dengue-fever may be related to the likelihood of patients suffering from imported cases of dengue-fever staying within local communities. Conclusion. Given the correlations found between imported and indigenous dengue-fever cases, as well as the relationship between disease concealment period and risk of indigenous dengue-fever, the major priorities for disease control remain prevention of disease importation and efficient identification of dengue cases within high-risk communities.
Repeat Induced Abortion And Associated Factors Among Women Seeking Abortion Care Services At Debre Markos Town Health Institutions, Amhara Regional State, Ethiopia, 2017.
Authors: Waktola Mahlet Imana , Mekonen Dawit Gebeyehu , Nigussie Tewodros Seyoum , Cherkose Endeshaw Adimasu , Abate Addisu Taye 
Published: December 2019

Abstract

Objective the aim of this study was to assess the proportion and determinants of repeat induced abortion among women seeking abortion care services at Debremarkos town health institutions, Amhara regional state, Ethiopia, 2017.Result from the total 567-sample size, 547 women were participated in the study making a response rate of 96.5%. In this study 191 woman reported that they had at least one previous abortion, making the proportion of repeat induced abortion 34.9%. In multivariable logistic regression analysis; illiteracy (AOR=8.45, 95%CI; 1.85, 36.49), living in an urban area (AOR=5.14, 95%CI; 2.29, 11.53), having multiple sexual partner (AOR=6.16, 95%CI; 3.25, 11.68), consuming alcohol (AOR=2.77, 95%CI; 1.52, 5.05) and having a history of physical violence by a male partner (AOR=2.68, 95%CI; 1.45, 4.94) were significantly associated with repeat induced abortion at p value less than 0.05.
Transcriptomic study of pedicels from GA3-treated table grape genotypes with different susceptibility to berry drop reveals responses elicited in cell wall yield, primary growth and phenylpropanoids synthesis.
Authors: Meneses Marco , García-Rojas Miguel , Muñoz-Espinoza Claudia , Carrasco-Valenzuela Tomás , Defilippi Bruno , González-Agüero Mauricio , Meneses Claudio , Infante Rodrigo , Hinrichsen Patricio 
Published: December 2019

AbstractBackground Gibberellins (GA3) are the most sprayed growth regulator for table grape production worldwide, increasing berry size of seedless varieties through pericarp cell expansion. However, these treatments also exacerbate berry drop, which has a detrimental effect on the postharvest quality of commercialized clusters. Several studies have suggested that pedicel stiffening caused by GA3 would have a role in this disorder. Nevertheless, transcriptional and phenotypic information regarding pedicel responses to GA3 is minimal.Results Characterization of responses to GA3 treatments using the lines L23 and Thompson Seedless showed that the former was up to six times more susceptible to berry drop than the latter. GA3 also increased the diameter and dry matter percentage of the pedicel on both genotypes. Induction of lignin biosynthesis-related genes by GA3 has been reported, so the quantity of this polymer was measured. The acetyl bromide method detected a decreased concentration of lignin seven days after GA3 treatment, due to a higher cell wall yield of the isolated fractions of GA3-treated pedicel samples which caused a dilution effect. Thus, an initial enrichment of primary cell wall components in response to GA3 was suggested, particularly in the L23 background. A transcriptomic profiling was performed to identify which genes were associated with these phenotypic changes. This analysis identified 1,281 and 1,787 genes differentially upregulated by GA3 in L23 and cv. Thompson Seedless, respectively. Concomitantly, 1,202 and 1,317 downregulated genes were detected in L23 and cv. Thompson Seedless (FDR≤0.05). Gene ontology analysis of upregulated genes showed enrichment in pathways including phenylpropanoids, cell wall metabolism, xylem development, photosynthesis and the cell cycle at seven days post GA3 application. Twelve genes were characterized by qPCR and striking differences were observed between genotypes, mainly in genes related to cell wall synthesis.Conclusions High levels of berry drop are related to an early strong response of primary cell wall synthesis in the pedicel promoted by GA3 treatment. Genetic backgrounds can produce similar phenotypic responses to GA3, although there is considerable variation in the regulation of genes in terms of which are expressed, and the extent of transcript levels achieved within the same time frame.
Clinical and microbiological effect of pulsed xenon ultraviolet disinfection to reduce multidrug-resistant organisms in the intensive care unit in a Japanese hospital: a before-after study
Authors: Morikane Keita , Suzuki Shoko , Yoshioka Jun , Yakuwa Jun , Nakane Masaki , Nemoto Kenji 
Published: December 2019

Abstract
Background No-touch environmental disinfection using ultraviolet devices has been highlighted in the past several years to control the transmission of multidrug-resistant organisms (MDROs). However, its effectiveness in non-US healthcare settings is yet to be examined. This study aimed to evaluate the effectiveness of disinfection by portable pulsed xenon ultraviolet (PX-UV) devices in controlling transmission of MDROs in a non-US healthcare setting. Methods All patients admitted in the intensive care unit in a 629-bed tertiary referral hospital in Japan from August 2016 to February 2019 were enrolled. During the study period, PX-UV disinfection was added to manual terminal cleaning after every patient transfer/discharge. For microbiological evaluation, surfaces were selected for sampling by contact plates before/after manual cleaning and after PX-UV. After overnight incubation, colonies on the plates were counted. Results The incidence of newly acquired methicillin-resistant Staphylococcus aureus (MRSA) declined significantly (13.8 to 9.9 per 10,000 patient days, incidence rate ratio 0.71, p=0.002), as well as that of newly acquired drug-resistant Acinetobacter (48.5 to 18.1, 0.37, p<0.001). The percent reduction of the microbiological burden by manual cleaning was 81%, but a further 59% reduction was achieved by PX-UV. Conclusions PX-UV is effective in further reducing the microbial burden and controlling MDROs in a non-US healthcare setting.