bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decline of ovarian function in patients with rheumatoid arthritis: serum anti-Müllerian hormone levels in a longitudinal cohort
Authors: Brouwer Jenny , Dolhain Radboud J E M , Hazes Johanna M W , Erler Nicole S , Visser Jenny A , Laven Joop S E 
Published: October 2020

ObjectiveRheumatoid arthritis (RA) often affects women in their fertile age, and is known to compromise female fertility. Serum anti-Müllerian hormone (AMH) levels are a proxy for the total number of primordial follicles, and a reliable predictor of the age at menopause. Our objective was to study the longitudinal intra-individual decline of serum AMH levels in female RA patients.MethodsFemale RA patients from a nationwide prospective cohort (2002–2008) were re-assessed in 2015–2016. Serum AMH levels were measured using the picoAMH assay and compared with healthy controls. A linear mixed model (LMM) was built to assess the effect of RA-related clinical factors on the decline of AMH levels.ResultsA group of 128 women were re-assessed at an age of 42.6±4.4 years, with a median disease duration of 15.8 (IQR 12.7–21.5) years. The time between first and last AMH assessments was 10.7±1.8 (range 6.4–13.7) years. Participants represented a more fertile selection of the original cohort. At follow-up, 39% of patients had AMH levels below the 10th percentile of controls (95% CI 31% to 48%), compared with 16% (95% CI 9.3% to 22%) at baseline. The LMM showed a significant decline of AMH with increasing age, but no significant effect of RA-related factors on AMH.ConclusionAMH levels in RA patients showed a more pronounced decline over time than expected, supporting the idea that in chronic inflammatory conditions, reproductive function is compromised, resulting in a faster decline of ovarian function over time and probably an earlier age at menopause.
Effects of dosage of warm mix asphalt additive on stiffness, cracking susceptibility, and moisture sensitivity characteristics
Authors: Materu Salvatory , Shalaby Ahmed , Ghazy Ahmed 
Published: October 2020

Warm mix asphalt (WMA) technology has the capability of lowering asphalt mixing and compacting temperature by 30 °C or more without compromising the performance of asphalt pavement. This results to a lower cooling rate that allows for long haul, and sufficient compaction time. The objective of this study is to evaluate the effectiveness of the common chemical additives on the properties of WMA mixtures through field and laboratory testing programs. Three dosages (0.3, 0.5, and 0.7% by weight of asphalt cement) were used without changing the job mix formula. Among the different additive dosage used, 0.5% had a better overall performance. For example, the moisture sensitivity test for the 0.5% WMA indicated the highest tensile strength ratio; subsequently, low moisture damage. All WMA mixtures had low rutting resistance potential and higher cracking resistance compared to conventional mix.
Charged-pion production in $$\mathbf {Au+Au}$$ collisions at $$\sqrt{\mathbf {s}_{\mathbf {NN}}} = 2.4~{\mathbf {GeV}}$$
Authors:   HADES Collaboration, Adamczewski-Musch J. , Arnold O. , Behnke C. , Belounnas A. , Belyaev A. , Berger-Chen J. C. , Blanco A. , Blume C. , Böhmer M. , Bordalo P. , Chernenko S. , Chlad L. , Ciepał I. , Deveaux C. , Dreyer J. , Epple E. , Fabbietti L. , Fateev O. , Filip P. , Fonte P. , Franco C. , Friese J. , Fröhlich I. , Galatyuk T. , Garzón J. A. , Gernhäuser R. , Gläßel S. , Golubeva M. , Greifenhagen R. , Guber F. , Gumberidze M. , Harabasz S. , Heinz T. , Hennino T. , Hlavac S. , Höhne C. , Holzmann R. , Ierusalimov A. , Ivashkin A. , Kämpfer B. , Karavicheva T. , Kardan B. , Koenig I. , Koenig W. , Kohls M. , Kolb B. W. , Korcyl G. , Kornakov G. , Kornas F. , Kotte R. , Kugler A. , Kunz T. , Kurepin A. , Kurilkin A. , Kurilkin P. , Ladygin V. , Lalik R. , Lapidus K. , Lebedev A. , Lopes L. , Lorenz M. , Mahmoud T. , Maier L. , Malige A. , Mangiarotti A. , Markert J. , Matulewicz T. , Maurus S. , Metag V. , Michel J. , Mihaylov D. M. , Morozov S. , Müntz C. , Münzer R. , Naumann L. , Nowakowski K. , Parpottas Y. , Pechenov V. , Pechenova O. , Petukhov O. , Piasecki K. , Pietraszko J. , Przygoda W. , Pysz K. , Ramos S. , Ramstein B. , Rathod N. , Reshetin A. , Rodriguez-Ramos P. , Rosier P. , Rost A. , Rustamov A. , Sadovsky A. , Salabura P. , Scheib T. , Schuldes H. , Schwab E. , Scozzi F. , Seck F. , Sellheim P. , Selyuzhenkov I. , Siebenson J. , Silva L. , Singh U. , Smyrski J. , Sobolev Yu. G. , Spataro S. , Spies S. , Ströbele H. , Stroth J. , Sturm C. , Svoboda O. , Szala M. , Tlusty P. , Traxler M. , Tsertos H. , Usenko E. , Wagner V. , Wendisch C. , Wiebusch M. G. , Wirth J. , Wójcik D. , Zanevsky Y. , Zumbruch P. 
Published: October 2020

AbstractWe present high-statistic data on charged-pion emission from Au + Au collisions at $$\sqrt{s_{\mathrm{NN}}} = 2.4~\hbox {GeV}$$

s
NN

=
2.4

GeV

(corresponding to $$E_{beam} = 1.23~\hbox {A GeV}$$

E

beam

=
1.23

A GeV

) in four centrality classes in the range 0–40% of the most central collisions. The data are analyzed as a function of transverse momentum, transverse mass, rapidity, and polar angle. Pion multiplicity per participating nucleon decreases moderately with increasing centrality. The polar angular distributions are found to be non-isotropic even for the most central event class. Our results on pion multiplicity fit well into the general trend of the available world data, but undershoot by $$2.5~\sigma $$

2.5

σ

data from the FOPI experiment measured at slightly lower beam energy. We compare our data to state-of-the-art transport model calculations (PHSD, IQMD, PHQMD, GiBUU and SMASH) and find substantial differences between the measurement and the results of these calculations.
Weak cosmic censorship conjecture for the novel 4D charged Einstein–Gauss–Bonnet black hole with test scalar field and particle
Authors: Yang Si-Jiang , Wan Jun-Jie , Chen Jing , Yang Jie , Wang Yong-Qiang 
Published: October 2020

AbstractRecent researches of the novel 4D Einstein–Gauss–Bonnet (EGB) gravity have attracted great attention. In this paper, we investigate the validity of the weak cosmic censorship conjecture for a novel 4D charged EGB black hole with test charged scalar field and test charged particle respectively. For the test charged field scattering process, we find that both extremal and near-extremal black holes cannot be overcharged. For the test charged particle injection, to first order, an extremal black hole cannot be overcharged while a near-extremal 4D charged EGB black hole can be destroyed. To second order, however, both extremal and near-extremal 4D charged EGB black holes can be overcharged for positive Gauss–Bonnet coupling constant; for negative Gauss–Bonnet coupling constant, an extremal black hole cannot be overcharged and the validity of the weak cosmic censorship conjecture for a near-extremal black hole depends on the Gauss–Bonnet coupling constant.
Is there evidence for a hotter Universe?
Authors: Bengaly Carlos A. P. , Gonzalez Javier E. , Alcaniz Jailson S. 
Published: October 2020

AbstractThe measurement of present-day temperature of the Cosmic Microwave Background (CMB), $$T_0 = 2.72548 \pm 0.00057$$

T
0

=
2.72548
±
0.00057

K (1$$\sigma $$
σ
), made by the Far-InfraRed Absolute Spectrophotometer (FIRAS) as recalibrated by the Wilkinson Microwave Anisotropy Probe (WMAP), is one of the most precise measurements ever made in Cosmology. On the other hand, estimates of the Hubble Constant, $$H_0$$

H
0

, obtained from measurements of the CMB temperature fluctuations assuming the standard $$\varLambda $$
Λ
CDM model exhibit a large ($$4.1\sigma $$

4.1
σ

) tension when compared with low-redshift, model-independent observations. Recently, some authors argued that a slightly change in $$T_0$$

T
0

could alleviate or solve the $$H_0$$

H
0

-tension problem. Here, we investigate evidence for a hotter or colder universe by performing an independent analysis from currently available temperature-redshift T(z) measurements. Our analysis (parametric and non-parametric) shows a good agreement with the FIRAS measurement and a discrepancy of $$\ge 1.9\sigma $$

≥
1.9
σ

from the $$T_0$$

T
0

values required to solve the $$H_0$$

H
0

tension. This result reinforces the idea that a solution of the $$H_0$$

H
0

-tension problem in fact requires either a better understanding of the systematic errors on the $$H_0$$

H
0

measurements or new physics.
Characters and group invariant polynomials of (super)fields: road to “Lagrangian”
Authors: Banerjee Upalaparna , Chakrabortty Joydeep , Prakash Suraj , Rahaman Shakeel Ur 
Published: October 2020

AbstractThe dynamics of the subatomic fundamental particles, represented by quantum fields, and their interactions are determined uniquely by the assigned transformation properties, i.e., the quantum numbers associated with the underlying symmetry of the model under consideration. These fields constitute a finite number of group invariant operators which are assembled to build a polynomial, known as the Lagrangian of that particular model. The order of the polynomial is determined by the mass dimension. In this paper, we have introduced an automated $${\texttt {Mathematica}}^{\tiny \textregistered }$$

Mathematica

®

package, GrIP, that computes the complete set of operators that form a basis at each such order for a model containing any number of fields transforming under connected compact groups. The spacetime symmetry is restricted to the Lorentz group. The first part of the paper is dedicated to formulating the algorithm of GrIP. In this context, the detailed and explicit construction of the characters of different representations corresponding to connected compact groups and respective Haar measures have been discussed in terms of the coordinates of their respective maximal torus. In the second part, we have documented the user manual of GrIP that captures the generic features of the main program and guides to prepare the input file. We have attached a sub-program CHaar to compute characters and Haar measures for $$SU(N), SO(2N), SO(2N+1), Sp(2N)$$

S
U
(
N
)
,
S
O
(
2
N
)
,
S
O
(
2
N
+
1
)
,
S
p
(
2
N
)

. This program works very efficiently to find out the higher mass (non-supersymmetric) and canonical (supersymmetric) dimensional operators relevant to the effective field theory (EFT). We have demonstrated the working principles with two examples: the standard model (SM) and the minimal supersymmetric standard model (MSSM). We have further highlighted important features of GrIP, e.g., identification of effective operators leading to specific rare processes linked with the violation of baryon and lepton numbers, using several beyond standard model (BSM) scenarios. We have also tabulated a complete set of dimension-6 operators for each such model. Some of the operators possess rich flavour structures which are discussed in detail. This work paves the way towards BSM-EFT.
Completely 0-simple semigroup with the basis property
Authors: Al-Dayel Ibrahim , Al Khalaf Ahmad 
Published: October 2020

A semigroup [Formula: see text] is said to have the Basis Property if for any subsemigroup [Formula: see text] of a semigroup [Formula: see text], any two bases for [Formula: see text] have the same cardinality. The structure of completely [Formula: see text]-simple semigroup with the Basis Property is described. In particular, we proved that each completely [Formula: see text]-simple semigroup [Formula: see text] has the Basis Property if and only if [Formula: see text] satisfies one of the following conditions: (1) [Formula: see text] is produced from a completely simple semigroup with adjoint zero. (2) [Formula: see text] is an isomorphic to Rees’s semigroup [Formula: see text] over a group [Formula: see text] with sandwich matrix [Formula: see text] such that [Formula: see text], [Formula: see text], in addition [Formula: see text] has a zero in every row and column.
Patients With Acute Ischemic Stroke Who Receive Brain Magnetic Resonance Imaging Demonstrate Favorable In‐Hospital Outcomes
Authors: Lee Hwan , Yang Yifeng , Liu Baoqiong , Castro Simon A. , Shi Tiantian 
Published: October 2020

Background
Use of inpatient brain magnetic resonance imaging (MRI) in patients with acute ischemic stroke is highly institution dependent and has been associated with increased length and cost of hospital stay. We examined whether inpatient brain MRI in patients with acute ischemic stroke is associated with improved clinical outcomes to justify its resource requirements.

Methods and Results

The National Inpatient Sample database was queried retrospectively to find 94 003 patients who were admitted for acute ischemic stroke and then received inpatient brain MRI between 2012 and 2014. Multivariable regression analysis was performed with respect to a control group to assess for differences in the rates of inpatient mortality and complications, as well as the length and cost of hospital stay based on brain MRI use. Inpatient brain MRI was independently associated with lower rates of inpatient mortality (1.67% versus 3.09%; adjusted odds ratio [OR], 0.60; 95% CI, 0.53–0.68;
P
<0.001), gastrostomy (2.28% versus 2.89%; adjusted OR, 0.82; 95% CI, 0.73–0.93;
P
<0.001), and mechanical ventilation (1.97% versus 2.82%; adjusted OR, 0.68; 95% CI, 0.60–0.77;
P
<0.001). Brain MRI was independently associated with ≈0.32 days (8%) and $1131 (11%) increase in the total length (
P
<0.001) and cost (
P
<0.001) of hospital stay, respectively.

Conclusions
Inpatient brain MRI in patients with acute ischemic stroke is associated with substantial decrease in the rates of inpatient mortality and complications, at the expense of marginally increased length and cost of hospitalization.
Successful resuscitation after hyperkalemic cardiac arrest during liver transplantation by converting veno-venous bypass to veno-arterial ECMO
Authors: Van Hoof Lucas , Rega Filip , Devroe Sarah , Degezelle Karlien , Pirenne Jacques , Neyrinck Arne 
Published: October 2020

Introduction: Intraoperative cardiac arrest (ICA) is a feared complication during liver transplantation (LTx), typically occurring during reperfusion. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been used for post-reperfusion cardiac arrest. Case report: We present a case of successful resuscitation after hyperkalemic ICA during the pre-anhepatic phase of a second liver transplantation by converting veno-venous bypass (VVB) to VA-ECMO. Discussion: While this technique has been recommended for ICA during reperfusion, it has never been reported during the pre-anhepatic phase. VA-ECMO can be a lifesaving extension to cardiopulmonary resuscitation for ICA during LTx with beneficial neurological outcome by providing perfusion while the cause of ICA is reversed. Conclusion: Conversion of VVB to VA-ECMO should be considered in all patients who suffer from ICA during LTx with use of VVB. With VVB installed, conversion to VA-ECMO is fast and effective. If VVB is not used, early VA-ECMO should be considered for ICA.
Postmigratory Perceptions of Female Genital Mutilation: Qualitative Life History Research
Authors: Pastor-Bravo María del Mar , Almansa-Martínez Pilar , Jiménez-Ruiz Ismael 
Published: October 2020

Introduction Female genital mutilation/cutting (FGM/C) is a practice, in breach of human rights, which currently extends to European countries. Given that migration to a Western country can involve cultural change, the aim of the present study is to explore the experiences and perceptions of sub-Saharan women regarding FGM/C following migration to Spain. Method A qualitative exploratory research design utilizing life history methodology was applied. Participants ( n = 24) were recruited until data saturation was reached. Results Sub-Saharan women describe their experience of FGM/C. Once in Spain, they begin to demystify the justifications for which FGM/C is practiced and to break the taboo that surrounds the practice. Discussion Migration leads individuals to reflect on the traditional practices from their countries of origin. The nursing profession must accompany migrant women throughout their process of change and provide objective information from a position of cultural understanding, avoiding attitudes that might create a sense of revictimization while their resultant health consequences are being attended to.
Midterm Results of Fresh-Frozen Osteochondral Allografting for Osteochondral Lesions of the Talus
Authors: Chu Chung-Hua , Chen Ing-Ho , Yang Kai-Chiang , Wang Chen-Chie 
Published: October 2020

Background: Osteochondral lesions of the talus (OLT) are relatively common. Following the failure of conservative treatment, many operative options have yielded varied results. In this study, midterm outcomes after fresh-frozen osteochondral allograft transplantation for the treatment of OLT were evaluated. Methods: Twenty-five patients (12 women and 13 men) with a mean age 40.4 (range 18-70) years between 2009 and 2014 were enrolled. Of 25 ankles, 3, 13, 4, and 4 were involved with the talus at Raikin zone 3, 4, 6, and 7 as well as one coexisted with zone 4 and 6 lesion. The mean OLT area was 1.82 cm2 (range, 1.1-3.0). The mean follow-up period was 5.5 years (range, 4-9.3). Outcomes evaluation included the American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot score, visual analog scale score, and 12-item Short Form Health Survey (SF-12). Result: AOFAS ankle-hindfoot score increased from 74 preoperatively to 94 at 2 years postoperatively ( P < .001) and the SF-12 physical health component scores increased from 32 to 46 points ( P < .001). Incorporation was inspected in all patients in the latest follow-up, and graft subsidence and radiolucency were observed in 2 and 7 cases, respectively, whereas graft collapse and revision OLT graft were not observed. Bone sclerosis was found in 6 of 25 patients. Conclusion: With respect to midterm results, fresh, frozen-stored allograft transplantation might be an option in the management of symptomatic OLT. Level of Evidence: Level IV, retrospective case series.
Early Failures of Polyvinyl Alcohol Hydrogel Implant for the Treatment of Hallux Rigidus
Authors: Shimozono Yoshiharu , Hurley Eoghan T. , Kennedy John G. 
Published: October 2020

Background: The purpose of this study was to evaluate the clinical and radiological outcomes following a polyvinyl alcohol hydrogel implant in the treatment of hallux rigidus. Methods: A retrospective cohort study investigating patients treated with a polyvinyl alcohol hydrogel implant for hallux rigidus was performed. Clinical outcomes were evaluated with the Foot and Ankle Outcomes Score (FAOS) and visual analog scale (VAS) score at the final follow-up. Plain radiographs were assessed postoperatively. Eleven patients (11 feet) with a mean follow-up of 20.9 months (range, 14-27 months) were included. The mean age was 60.3 years. Results: All FAOS subscales showed pre- to postoperative improvements, but there was no statistical significance in all subscales. The mean VAS score showed improvement from 4.1 to 3.0 ( P = .012). On postoperative plain radiographs, implant subsidence was observed 60% (6/10) at 4 weeks after surgery and 90% (9/10) at the final follow-up. Fifty percent (5/10) showed radiologic lucency around the implant. Forty percent (4/10) had erosion of the proximal phalanx of the great toe. Four patients (36%) reported no improvement following surgery at the final follow-up, which were considered as failures. Three patients required additional surgery related to the implants. An additional patient is waiting to revise the implant. Conclusion: Our current cohort study demonstrated a high failure rate with the polyvinyl alcohol hydrogel implant in patients with hallux rigidus. Significant radiologic subsidence with lysis around the implant, erosion of the proximal phalanx countersurface, and implant wear are harbingers for concern in the long term. Level of Evidence: Level IV, case series.
Analysis of Changes in Cancer-Related Fatigue of Breast Cancer Patients Receiving an Integrative Medicine Program
Authors: Schad Friedemann , Thronicke Anja , von Trott Phillipp , Oei Shiao Li 
Published: October 2020

Introduction: Cancer-related fatigue (CRF) occurs frequently in breast cancer patients. The aim of this real-world study was to analyze the longitudinal changes of CRF in breast cancer patients receiving an integrative medicine program, which includes the application of non-pharmacological interventions (NPIs) and Viscum album L. (VA) extracts. Methods: All data were collected from the clinical register of the Network Oncology of a German certified breast cancer center of the Gemeinschaftskrankenhaus Havelhöhe (GKH). Primary breast cancer patients, treated upon initial diagnosis with integrated NPIs, comprising art and exercise therapy, nursing interventions, and educational components, during their hospital stay, and who had answered the German Cancer-Fatigue Scale (CFS-D) questionnaire at first diagnosis and 12 months later, were included. The associations between NPIs and CFS-D changes were analyzed with adjusted multivariable regression analyses, considering received treatment regimens and demographic variables, using the software R. Results: 231 female breast cancer patients of all tumor stages were evaluated. While chemotherapy exhibited significant severe deterioration, add-on VA applications seem to partially mitigate this impairment on CRF. 36 separate multivariable regression analyses for all NPIs showed that in particular significant associations between CFS-D improvements and the interventions nursing compresses (6 point change; P = .0002; R² = 28%) or elaborate consultations and life review (ECLR) (4 point change; P = .0002; R² = 25%) were observed. Conclusions: Breast cancer patients benefit from a hospital-based integrative medicine program. To alleviate fatigue symptoms during oncological therapy, an expansion of this concept should be developed in the future.
A Music-Based Digital Therapeutic: Proof-of-Concept Automation of a Progressive and Individualized Rhythm-Based Walking Training Program After Stroke
Authors: Hutchinson Karen , Sloutsky Regina , Collimore Ashley , Adams Benjamin , Harris Brian , Ellis Terry D. , Awad Louis N. 
Published: October 2020

Background The rhythm of music can entrain neurons in motor cortex by way of direct connections between auditory and motor brain regions. Objective We sought to automate an individualized and progressive music-based, walking rehabilitation program using real-time sensor data in combination with decision algorithms. Methods A music-based digital therapeutic was developed to maintain high sound quality while modulating, in real-time, the tempo (ie, beats per minute, or bpm) of music based on a user’s ability to entrain to the tempo and progress to faster walking cadences in-sync with the progression of the tempo. Eleven individuals with chronic hemiparesis completed one automated 30-minute training visit. Seven returned for 2 additional visits. Safety, feasibility, and rehabilitative potential (ie, changes in walking speed relative to clinically meaningful change scores) were evaluated. Results A single, fully automated training visit resulted in increased usual (∆ 0.085 ± 0.027 m/s, P = .011) and fast (∆ 0.093 ± 0.032 m/s, P = .016) walking speeds. The 7 participants who completed additional training visits increased their usual walking speed by 0.12 ± 0.03 m/s after only 3 days of training. Changes in walking speed were highly related to changes in walking cadence ( R2 > 0.70). No trips or falls were noted during training, all users reported that the device helped them walk faster, and 70% indicated that they would use it most or all of the time at home. Conclusions In this proof-of-concept study, we show that a sensor-automated, progressive, and individualized rhythmic locomotor training program can be implemented safely and effectively to train walking speed after stroke. Music-based digital therapeutics have the potential to facilitate salient, community-based rehabilitation.