bluuebunny/crossref_metadata_2025_split huggingface dataset:
Challenging and redesigning a new model to explain intention to leave nursing
Authors: Slater Paul , Roos Mervi , Eskola Suvi , McCormack Brendan , Hahtela Nina , Kurjenluoma Kaisa , Suominen Tarja 
Published: June 2020

BackgroundIt is important to have a full and detailed understanding of the factors that influence intention to leave nursing. It has been shown to be the best predictor of actual turnover, and turnover has a significant financial impact and also on the provision of care.AimsThe aim is to examine the impact of predictive work environment factors on nurses’ intention to leave their position and to explore contributing factors.MethodsCross‐sectional survey using a convenience sample (n = 605) of Finnish nurses drawn from five clinical settings. The Nursing Context Index, an internationally used and psychometrically validated tool, was used to measure workplace practice environment, work stress, job satisfaction and intention to leave. A response rate of 29.4% was achieved, exceeding power calculation estimates.ResultsPersonal satisfaction and satisfaction with profession and resources, and organisational commitment were significantly related to intention to leave. Younger nurses reported higher levels of intention to leave and there was variability among clinical specialties. Measures of stress and practice environment had no significant relationship with intention to leave.DiscussionThis study provides a new theoretical model for understanding intention to leave. Having a better understanding of the factors that may help reduce intention to leave allows for targeted interventions to be developed and implemented. This would help reduce the personal and financial implications associated with turnover.Implications for practice, policy, management and educationThe findings have significant implications for all aspects of nursing. Educators need to prepare new nursing staff for the working environment; policymakers must ensure that nursing satisfaction is promoted to strengthen organisational commitment and nurse managers and leaders respond accordingly in implementing effective interventions.
Reconceptualizing the Enclave: Measuring Success Among Latino‐Owned Businesses
Authors: Orozco Marlene 
Published: June 2020

ObjectiveThis study considers whether ethnic economy characteristics, such as serving a primarily co‐ethnic customer base or having a business located among co‐ethnics (i.e., enclaves), promote greater success for Latino‐owned businesses. Previous studies offer unclear accounts of how the enclave is measured and have suffered from issues of selection bias. I validate spatial measures with additional measures related to ethnic economies.MethodsRather than starting with a predetermined geographic location, I leverage a national business sample, the 2018 Survey of U.S. Latino Business Owners (N = 4,024), to estimate an ordered logistic regression that predicts the successful characteristics of the economic niche under which Latino‐owned businesses operate.ResultsI find Latino‐owned businesses have the greatest profitability selling Latino products but see the greatest revenue returns serving mostly non‐Latino customers. I uncover the largest effect sizes among Latino‐owned businesses that mainly employ co‐ethnics rather than among businesses located within a defined geography.ConclusionThese findings suggest ethnic economies are not geographically bounded, as previously theorized, but rather culturally based.
SARS‐CoV‐2 infection in kidney transplant recipients: Experience of the italian marche region
Authors: Maritati Federica , Cerutti Elisabetta , Zuccatosta Lina , Fiorentini Alessandro , Finale Carolina , Ficosecco Marta , Cristiano Fabrizio , Capestro Alessandro , Balestra Emilio , Taruscia Domenica , Vivarelli Marco , Donati Abele , Perna Gian Piero , Giacometti Andrea , Tavio Marcello , Onesta Maicol , Di Sante Laura , Ranghino Andrea 
Published: June 2020

AbstractBackgroundInfection related to Coronavirus‐19 (CoV‐2) is pandemic affecting more than 4 million people in 187 countries worldwide. By May 10, 2020, it caused more than 280 000 deaths all over the world. Preliminary data reported a high prevalence of CoV‐2 infection and mortality due to severe acute respiratory syndrome related CoV‐2 (SARS‐CoV‐2) in kidney‐transplanted patients (KTRs). Nevertheless, the outcomes and the best treatments for SARS‐CoV‐2‐affected KTRs remain unclear.MethodsIn this report, we describe the clinical data, the treatments, and the outcomes of 5 KTRs with SARS‐CoV‐2 admitted to our hospital in Ancona, Marche region, Italy, from March 17 to present. Due to the severity of SARS‐CoV‐2, immunosuppression with calcineurin inhibitors, antimetabolites, and mTOR‐inhibitors were stopped at the admission. All KTRs were treated with low‐dose steroids. 4/5 KTRs were treated with hydroxychloroquine. All KTRs received tocilizumab up to one dose.ResultsOverall, the incidence of SARS‐CoV‐2 in KTRs in the Marche region was 0.85%. 3/5 were admitted in ICU and intubated. One developed AKI with the need of CRRT with Cytosorb. At present, two patients died, two patients were discharged, and one is still inpatient in ICU.ConclusionsThe critical evaluation of all cases suggests that the timing of the administration of tocilizumab, an interleukin‐6 receptor antagonist, could be associated with a better efficacy when administered in concomitance to the drop of the oxygen saturation. Thus, in SARS‐CoV‐2‐affected KTRs, a close biochemical and clinical monitoring should be set up to allow physicians to hit the virus in the right moment such as a sudden reduction of the oxygen saturation and/or a significant increase in the laboratory values such as D‐dimer.
Numerical Study on Flow Field Distribution Regularities in Wet Gas Desulfurization Tower Changing Inlet Gas/Liquid Feature Parameters
Authors: Deng Qingbo , Ran Jingyu , Niu Juntian , Yang Zhongqing , Pu Ge , Yang Lin 
Published: June 2020

Abstract
In the wet gas desulphurization tower, the uneven distribution of flue gas will have a negative impact on the desulphurization process. The effect should be counterbalanced by increasing the amount of slurry spray, which will increase the operating costs. Adding deflectors will also bring negative effects and increase the expenses. In order to avoid the negative influence, this paper studied the flow field distribution regularities of flue gas in desulfurization tower at different inlet velocities and liquid–gas ratios. Velocity field distribution character was evaluated by uniformity index. The results showed that the flue gas forms a vortex in the tower and a local high-speed gas-flow appears in the empty tower, which led to a poor flow field uniformity. After adding the spray, the flow field is integrated into uniformity. The slurry has obvious integration effect on flue gas. The lower the inlet flue gas velocity is, the higher the velocity uniform index in the desulfurization tower will be, and the heat exchange between the two phases more sufficient. To achieve the same uniformity, the less amount of slurry is required while the inlet velocity is slower. The energy consumption and material consumption of the desulfurization system can be effectively reduced by reducing the import speed reasonably.
Study of Aerodynamic Performance and Power Output for Residential-Scale Wind Turbines
Authors: Hasan Alaa S. , Abousabae Mohammed , Salem Abdel Rahman , Amano Ryoichi S. 
Published: June 2020

Abstract
This study presents the rotor blade airfoil analysis of residential-scale wind turbines. On this track, four new airfoils (GOE 447, GOE 446, NACA 6412, and NACA 64(3)-618) characterized by their high lift-to-drag ratios (161.3, 148.7, 142.7, and 136.3, respectively). These new airfoils are used to generate an entire 7 m long blades for three-bladed rotor horizontal axis wind turbine models tested numerically at low, medium, and rated wind speeds of 7.5, 10, and 12.5 m/s, respectively, with a design tip speed ratio of 7. The criterion to judge each model’s performance is power output. Thus, the blades of the model that produce the highest power are selected to undergo a tip modification (winglet) and leading-edge modification (tubercles), seeking power improvement. It is found that the GOE 447 airfoil outperformed the other three airfoils at all tested wind speeds. Thus, it is opted for adding winglets and tubercles. At 12.5 m/s, winglet design produced 5% more power, while tubercles produced 5.5% more power than the GOE 447 baseline design. Furthermore, the computational domain is divided into two regions: rotating (the disc that encloses the rotor) and stationary (the rest of the flow domain). Meanwhile, the numerical model is validated against the experimental velocity measurements. Since Reynolds-averaged Navier–Stokes with k–ω shear stress transport turbulence model can capture the laminar-to-turbulent boundary layer transition, it is used in the 18 simulations of the current work. However, large eddy simulation (LES) can deal successfully with the various scale eddies resulting from the rotor blades and its interactions with the surrounding flow. Thus, the LES was used in the six simulations done at the rated wind speed. LES power output calculation is 7.9% to 11.9% higher than the RANS power output calculation.
Reducing Instrumentation Errors Caused by Circumferential Flow-Field Variations in Multistage Axial Compressors
Authors: Chilla M. , Pullan G. , Gallimore S. 
Published: June 2020

Abstract
The effects of blade row interactions on stator-mounted instrumentation in axial compressors are investigated using unsteady numerical calculations. The test compressor is an eight-stage machine representative of an aero-engine core compressor. For the unsteady calculations, a 180-deg sector (half-annulus) model of the compressor is used. It is shown that the time-mean flow field in the stator leading edge planes is circumferentially nonuniform. The circumferential variations in stagnation pressure and stagnation temperature, respectively, reach 4.2% and 1.1% of the local mean. Using spatial wave number analysis, the incoming wakes from the upstream stator rows are identified as the dominant source of the circumferential variations in the front and middle of the compressor, while toward the rear of the compressor, the upstream influence of the eight struts in the exit duct becomes dominant. Based on three circumferential probes, the sampling errors for stagnation pressure and stagnation temperature are calculated as a function of the probe locations. Optimization of the probe locations shows that the sampling error can be reduced by up to 77% by circumferentially redistributing the individual probes. The reductions in the sampling errors translate to reductions in the uncertainties of the overall compressor efficiency and inlet flow capacity by up to 50%. Recognizing that data from large-scale unsteady calculations are rarely available in the instrumentation phase for a new test rig or engine, a method for approximating the circumferential variations with single harmonics is presented. The construction of the harmonics is based solely on the knowledge of the number of stators in each row and a small number of equispaced probes. It is shown how excursions in the sampling error are reduced by increasing the number of circumferential probes.
Coolant Jets Interaction in Effusion Cooling System: Experimental and Numerical Study
Authors: Jiang Y. , Murray A. V. , Ireland P.T. , di Mare L. 
Published: June 2020

AbstractThe interaction of coolant jets is significant in effusion settings as a result of the short streamwise and spanwise distance between films. This complicates the design of effusion cooling devices because computing the interaction between numerous, closely spaced rows of films is a challenging task. A flat plate effusion cooling model is investigated at both low and high blowing ratios. Pressure-sensitive paint (PSP) is used to measure film effectiveness. Computational fluid dynamics (CFD) calculations are performed to examine the cooling flow features in detail. The mesh sensitivity is studied to demonstrate the effect of mesh size on film effectiveness. The solution obtained by coarse mesh may not capture the correct trend with blowing ratio variation. Results of the computational work by fine mesh demonstrate good agreement with the measured effectiveness. Coolant jets interaction is also investigated. The profile of quantities such as velocity, temperature, kinetic energy, and Reynolds stress at several locations in the flow field is compared. The boundary layer profiles are scaled by the thermal boundary layer thickness to study the feature of heat transfer. It is observed that profiles of the flow quantities are self-similar. Two distinct scalings are found: an outer scaling based on boundary layer thickness which collapses the upper part of the profiles; an inner scaling which collapses the profiles at distances from the wall comparable to the penetration depth of a single jet. The latter scaling is based on the distance from the wall to the minimum temperature profile. This distance identifies the location of the coolant leaving the effusion cooling device.
The Impact of Combustor Turbulence on Turbine Loss Mechanisms
Authors: Folk Masha , Miller Robert J. , Coull John D. 
Published: June 2020

Abstract
A blade row that is located downstream of a combustor has an extremely high turbulence intensity at the inlet, typically above 10%. The peak turbulent length scale is also high, at around 20% of the chord of the downstream blade row. In a combustor, the turbulence is created by impinging jets in crossflow. This may result in the turbulence being anisotropic in nature. The aim of this paper is to investigate the effect of combustor turbulence on the loss mechanisms which occur in a turbine blade row. The paper has a number of important findings. The combustor turbulence is characterized and is shown to be isotropic in nature. It shows that, when no pressure gradient is present, combustor turbulence increases the loss of a turbulent boundary layer by 22%. The mechanism responsible for this change is shown to be a deep penetration of the turbulence into the boundary layer. It shows that the presence of combustor turbulence increases the profile loss and endwall loss in the turbine cascade studied by 37% and 47%, respectively. The presence of combustor turbulence also introduces a freestream loss resulting in the total loss of the turbine cascade rising by 47%. When these loss mechanisms were applied to the vane alone, of an engine representative high-pressure turbine, it was found to result in a 1.3% reduction in stage efficiency.
Topical Sodium Bicarbonate: No Improvement in Blood Buffering Capacity or Exercise Performance
Authors: McKay Alannah K.A. , Peeling Peter , Binnie Martyn J. , Goods Paul S.R. , Sim Marc , Cross Rebecca , Siegler Jason 
Published: June 2020

Purpose: To assess the efficacy of a topical sodium bicarbonate (0.3 g/kg body weight NaHCO3) application (PR lotion; Amp Human) on blood buffering capacity and performance in recreationally active participants (study A) and moderately trained athletes (study B). Methods: In Study A, 10 participants completed 2 experimental trials: oral NaHCO3 (0.3 g/kg body weight + placebo lotion) or PR lotion (0.9036 g/kg body weight + oral placebo) applied 90 minutes prior to a cycling task to exhaustion (30-s sprints at 120% peak power output with 30-s rest). Capillary blood was collected and analyzed for pH, bicarbonate, and lactate every 10 minutes throughout the 90-minute loading period and postexercise at 5, 10, and 15 minutes. In Study B, 10 cyclists/triathletes completed 2 experimental trials, applying either PR or placebo lotion 30 minutes prior to a cycling performance task (3 × 30-s maximal sprints with 90-s recovery). Capillary blood samples were collected at baseline, preexercise, and postexercise and analyzed as per study A. Results: In Study A, pH and bicarbonate were significantly elevated from baseline after 10 minutes in the oral NaHCO3 condition and throughout recovery compared with no elevation in the PR lotion condition (P < .001). No differences in cycling time occurred between PR lotion (349 [119] s) and oral NaHCO3 (363 [80] s; P = .697). In Study B, no differences in blood parameters, mean power (P = .108), or peak power (P = .448) were observed between conditions. Conclusions: PR lotion was ineffective in altering blood buffering capacity or enhancing performance in either trained or untrained individuals.
Teenage boy with bullous rash
Authors: Boyd McKenna Elizabeth , Yusuf Shabana 
Published: June 2020

­
A 14-year-old boy with recent antibiotic treatment for
tonsillitis, presented to the emergency department with 1-week
history of worsening rash and haemorrhagic bullae involving the
bilateral legs, trunk and hands (figures 1 and 2). Laboratory
results were significant for proteinuria (2+protein) and haematuria
(1+, 5–10 red blood cells/high power field); 24 hours urinary
protein and renal function were within normal limits. The patient
had an inconclusive skin biopsy.

Figure 1

Left and right images show palpable purpura with some
overlying bullae and vesiculation coalescing into plaques on
both lower extremities.

Figure 2

Left image shows rash on abdominal wall and right image
shows coalesced haemorrhagic bullae on hands.

Questions

What is the most probable diagnosis?

Bullous Ig A vasculitis

Meningococcemia

Bullous impetigo

Eosinophilic granulomatosis with
polyangiitis

Cryoglobulinemia

What is the best test which will establish the diagnosis in
this patient?

Renal ultrasound

Renal biopsy

Abdominal ultrasound

Creatinine clearance

What is first line of treatment in this patient?

Antibiotics

Steroids

Surgical debridement

Multispecialty consultation

Immunosuppressants such as azothioprine

What other systems can this condition affect besides the
skin?

Lungs

Kidneys

Spleen

Nervous system

A, B and D

Answers can be found on page 02.
Deep learning for natural language processing of free-text pathology reports: a comparison of learning curves
Authors: Senders Joeky T , Cote David J , Mehrtash Alireza , Wiemann Robert , Gormley William B , Smith Timothy R , Broekman Marike L D , Arnaout Omar 
Published: June 2020

IntroductionAlthough clinically derived information could improve patient care, its full potential remains unrealised because most of it is stored in a format unsuitable for traditional methods of analysis, free-text clinical reports. Various studies have already demonstrated the utility of natural language processing algorithms for medical text analysis. Yet, evidence on their learning efficiency is still lacking. This study aimed to compare the learning curves of various algorithms and develop an open-source framework for text mining in healthcare.MethodsDeep learning and regressions-based models were developed to determine the histopathological diagnosis of patients with brain tumour based on free-text pathology reports. For each model, we characterised the learning curve and the minimal required training examples to reach the area under the curve (AUC) performance thresholds of 0.95 and 0.98.ResultsIn total, we retrieved 7000 reports on 5242 patients with brain tumour (2316 with glioma, 1412 with meningioma and 1514 with cerebral metastasis). Conventional regression and deep learning-based models required 200–400 and 800–1500 training examples to reach the AUC performance thresholds of 0.95 and 0.98, respectively. The deep learning architecture utilised in the current study required 100 and 200 examples, respectively, corresponding to a learning capacity that is two to eight times more efficient.ConclusionsThis open-source framework enables the development of high-performing and fast learning natural language processing models. The steep learning curve can be valuable for contexts with limited training examples (eg, rare diseases and events or institutions with lower patient volumes). The resultant models could accelerate retrospective chart review, assemble clinical registries and facilitate a rapid learning healthcare system.
Co-occurrence of germline BRCA1 and CDH1 pathogenic variants
Authors: Villy Marie-Charlotte , Mouret-Fourme Emmanuelle , Golmard Lisa , Becette Véronique , Callet Nasrine , Marx Gilles , Colas Chrystelle , Lamarque Dominique , Rouleau Etienne , Stoppa-Lyonnet Dominique 
Published: June 2020

Introduction: We report a very rare case of familial breast cancer and diffuse gastric cancer, with germline pathogenic variants in both BRCA1 and CDH1 genes. To the best of our knowledge, this is the first report of such an association.Family description: The proband is a woman diagnosed with breast cancer at the age of 52 years. She requested genetic counselling in 2012, at the age of 91 years, because of a history of breast cancer in her daughter, her sister, her niece and her paternal grandmother and was therefore concerned about her relatives. Her sister and maternal aunt also had gastric cancer. She was tested for several genes associated with hereditary breast cancer.Results: A large deletion of BRCA1 from exons 1 to 7 and two CDH1 pathogenic cis variants were identified.Conclusion: This complex situation is challenging for genetic counselling and management of at-risk individuals.
ANALYSIS OF THE RESULTS OF STUDYING VOCATIONAL TRAINING OF FUTURE JUNIOR SPECIALISTS IN NURSING IN COLLEGES
Authors: Demianchuk М. R. 
Published: June 2020

The article reproduces the results of theoretical analysis of scientific studies which have been conducted to improve various aspects of vocational training of future junior specialists in nursing. The expediency of conducting a scientific and research work in the process of students’ study in medical colleges. It has been generalized that scholars studied problems of formation of professional competence, identity, readiness to different types of activities (research, project, promotion and implementation of healthy lifestyle ideas) in students of medical colleges.
It has been argued that in order to prove the effectiveness of the author’s methodic of vocational training of future junior specialists in nursing in medical colleges is necessary to organize experimental research and make analysis of its results. Comparative analysis of results at different stages of the scientific and research work contributed to establishing the effectiveness of the author’s methodic for organizing educational process.
The methods of questionnaire, testing, interviewing, observation, evaluation of students’ participation in solving professional-situational and simulation problems, etc. have been used to examine readiness of medical colleges students to professional work. In order to determine the formation of students’ motives and valuable orientations, to establish the level of knowledge, practical abilities, skills, readiness to professional development at all stages of research students from seven medical colleges have been involved.
The structure of readiness to professional activity of future junior specialists in nursing is presented. The results of the incoming and final controls to determine the levels of formation of all four components and readiness to professional work of students from control and experimental groups in general have been compared. The results of comparative analysis have stated that organization of training of students from experimental groups led to better results in vocational training of future junior specialists in nursing than in the case of traditional training in control groups.