bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Water-Alternating-Gas Injection on Gas and Water Production Control in Carbonate Reservoirs
Authors: Zhao Chuang , Song Zhaojie , Yao Yang , Li Yunbo , Liu Qiang , Qi Mei , Hou Jirui , Xu Likun , Han Bin , Song Liguang 
Published: November 2019

Abstract
The viscous fingering during continuous gas flooding and water channeling during water flooding will reduce the sweep efficiency and ultimately affect the displacement efficiency. In this paper, extensive experiments with different injection modes were conducted to study their effect on production performance.
Experimentally, based on the geological characteristics and development conditions of the target carbonate reservoir, a laboratory physical model was established to study the migration characteristics and occurrence state of the injected gas and water. The effect of different injection modes, including continuous gas flooding, water-alternating-gas (WAG) flooding and water flooding, on water and gas production and oil-displacement efficiency was investigated. Experimental results indicated that the rising of water cut of WAG flooding was much lower than that of water flooding, presenting a good effect on delaying water production. WAG injection showed a relatively plateau period of gas-oil ratio, indicating injected water delayed gas channeling. WAG flooding achieved the highest oil recovery, followed by continuous gas flooding and water flooding.
This study provided an improved understanding of gas and water channeling behavior, and proposed schemes for delaying gas channeling and improving gas flooding.
Recovery Potential and Mechanism Investigation of the Supercritical CO2 EOR in the Bakken Tight Formation
Authors: Wang Sai , Han Juan , Wang Yanbo , Ling Kegang , Jia Bao , Wang Hongsheng , Long Yifu 
Published: November 2019

Abstract
The low recovery of oil from the tight liquid-rich formations is still a main challenge for the tight reservoir. Thus, in order to break the chains and remove the obstacle such as the low recovery factor in the Bakken tight formation, even though the horizontal drilling and hydraulic fracturing technologies were already well applied in this field, the supercritical CO2 flooding was proposed as an immense potential recovery method for the production improvement.
In this research, we conducted a series of CO2 flooding experiments under various injection pressure (2500psi, 2800psi, 3000psi, 3500psi), to investigate the recovery potential of the core sample from Bakken tight formation. Also, the NMR analysis was processed of the core samples flooded with CO2 agent under the above injection pressure variables. The result comparison demonstrates that, with the supercritical CO2 injection pressure increase, the recovery factor gets incremental trend from 8.8% up to 33% recovery. Also, the macro pore and natural fracture system were proved to contribute more on the recovery potential. After reaching the miscible phase between the CO2 and oil in the sample, the hydrocarbon existed in the micro pores start the contribution to the recovery potential. Thus, The CO2 was identified as a potential recovery agent and the supercritical CO2 EOR method was proposed as the potential recovery technology due to the high recovery factor obtained in the immiscible and miscible processes.
Identification of genes and functional coexpression modules closely related to ulcerative colitis by gene datasets analysis
Authors: Zhu Jie , Wang Zheng , Chen Fengzhe , Liu Changhong 
Published: November 2019

BackgroundUlcerative colitis is a type of inflammatory bowel disease posing a great threat to the public health worldwide. Previously, gene expression studies of mucosal colonic biopsies have provided some insight into the pathophysiological mechanisms in ulcerative colitis; however, the exact pathogenesis is unclear. The purpose of this study is to identify the most related genes and pathways of UC by bioinformatics, so as to reveal the core of the pathogenesis.MethodsGenome-wide gene expression datasets involving ulcerative colitis patients were collected from gene expression omnibus database. To identify most close genes, an integrated analysis of gene expression signature was performed by employing robust rank aggregation method. We used weighted gene co-expression network analysis to explore the functional modules involved in ulcerative colitis pathogenesis. Besides, biological process and pathways analysis of co-expression modules were figured out by gene ontology enrichment analysis using Metascape.ResultsA total of 328 ulcerative colitis patients and 138 healthy controls were from 14 datasets. The 150 most significant differentially expressed genes are likely to include causative genes of disease, and further studies are needed to demonstrate this. Seven main functional modules were identified, which pathway enrichment analysis indicated were associated with many biological processes. Pathways such as ‘extracellular matrix, immune inflammatory response, cell cycle, material metabolism’ are consistent with the core mechanism of ulcerative colitis. However, ‘defense response to virus’ and ‘herpes simplex infection’ suggest that viral infection is one of the aetiological agents. Besides, ‘Signaling by Receptor Tyrosine Kinases’ and ‘pathway in cancer’ provide new clues for the study of the risk and process of ulcerative colitis cancerization.
Adaptation, phylogeny, and covariance in milk macronutrient composition
Authors: Blomquist Gregory E. 
Published: November 2019

BackgroundMilk is a complicated chemical mixture often studied through macronutrient concentrations of fat, protein, and sugar. There is a long-standing natural history tradition describing interspecific diversity in these concentrations. However, recent work has shown little influence of ecological or life history variables on them, aside from maternal diet effects, along with a strong phylogenetic signal.MethodsI used multivariate phylogenetic comparative methods to revisit the ecological and life history correlates of milk macronutrient composition and elaborate on the nature of the phylogenetic signal using the phylogenetic mixed model. I also identified clades with distinctive milks through nonparametric tests (KSI) and PhylogeneticEM evolutionary modeling.ResultsIn addition to the previously reported diet effects, I found increasingly aquatic mammals have milk that this is lower in sugar and higher in fat. Phylogenteic heritabilities for each concentration were high and phylogenetic correlations were moderate to strong indicating coevolution among the concentrations. Primates and pinnipeds had the most outstanding milks according to KSI and PhylogeneticEM, with perissodactyls and marsupials as other noteworthy clades with distinct selection regimes.DiscussionMammalian milks are diverse but often characteristic of certain higher taxa. This complicates identifying the ecological and life history correlates of milk composition using common phylogenetic comparative methods because those traits are also conservative and clade-specific. Novel methods, careful assessment of data quality and hypotheses, and a “phylogenetic natural history” perspective provide alternatives to these traditional tools.
The Prevalence of Polyparasitism in Oju, Local Government Area of Benue State, Nigeria
Authors: Akor J. O. , Obisike V. U. , Omudu E. A. , Imandeh G. N. 
Published: November 2019

Intestinal and urinary parasitic infections remain an important public health problem in the tropics where poor hygiene and sanitation are a norm rather than an exception. This study was designed to determine the prevalence and distribution of polyparasitic infections and to determine the impact of health education and treatments .Stool and urine samples from 350 participants were analyzed using macroscopic and microscopic direct stool examination of wet and Lugol’siodine preparations and Formal-ether concentration techniques and microscopic examination of simple centrifuged samples of urine. Out of the 350 participants, 101were infected with intestinal parasites with the male and female participants having 29 (66.0%), 41 (71.9%) prevalence of Entamoeba histolytica, 9 (20.5%), 8(14%) Eschericia coli, 2 (4.6), 6(10.5%) Trichomonas hominis and4 (9.1%), 2 (3.5%) Chilomastix mesnilli respectively. Out of the infected 101 participants, 14 of them had co-infection (polyparasitism). The result of polyparasitism in the Local Government is not significant (p>0.05).The overall infection before health education and treatment was high and least after health education and treatment 0(0%) (p<0.05). The results of this study indicated improper hygiene and sanitation conditions.
Protective Effect of Terminalia chebula Extract in Doxorubicin Induced Hyperlipidemic Rats
Authors: Muneer Aamina , Rabbani S. I. 
Published: November 2019

Aim: To study the anti-hyperlipidemic activity of Terminalia chebula in rats.
Study Design: Hyperlipidemia was induced by administering doxorubicin and the effect of Terminalia chebula was studied in male and female rats.
Methodology: Three doses of hydroalcoholic extract of Terminalia chebula (0.25, 0.5 and 1.0 gm/kg, body weight, per orally for 28 days) was tested against the doxorubicin (0.25 mg/kg, intra-peritoneal, 6 doses for 12 days) in male and female rats. Serum levels of total cholesterol, triglycerides, low-density lipoprotein (LDL-cholesterol) and high-density lipoprotein (HDL-cholesterol) were estimated. The antioxidant effect was determined by estimating the serum peroxidation levels. The result of the data was analyzed statistically by One-way Anova followed by Bonferroni comparison test. p<0.05 was considered to indicate the significance of the results.
Results and Discussion: The data indicated that a dose-dependent significant (p<0.05) reversal was observed in the doxorubicin-induced elevated total cholesterol, triglycerides, LDL-cholesterol and diminished HDL-cholesterol upon treatment with Terminalia chebula in male rats. In the female rats, only the highest tested dose of Terminalia chebula (1 gm/kg) produced the inhibitory effect in the elevated lipid levels without affecting significantly the HDL-cholesterol activity. Further, when Terminalia chebula was tested separately at 0.5 g before and after the administration of doxorubicin, a significant inhibition was observed in the post treatment in both sexes. Serum lipid peroxidation was found to be significantly (p<0.05) reduced by the extract compared to the doxorubicin group.
Conclusion: The results suggest that Terminalia chebula extract might have the potential to reduce doxorubicin-induced hyperlipidemic complications if administered together or after the doxorubicin therapy.
Gordon Dry Gin (Moringa Citrus Blend) Induce Adenomatous Hyperplasia in Female Sprague Dawley Rats
Authors: Eric E. U. , Alade T. O. , Eruvwahwe E. F. 
Published: November 2019

Objectives: This study aim to investigate the histopathological effects of binge consumed Gordon’s dry gin moringa citrus blend on the uterus of adult female dawley Sprague rats.
Materials: Fifty female rats (weighing range; 120±2.6 g - 250±3.5 g) were divided into four groups (A, B and C & D). Group A, B, C (15 animals each) were orally administered with Gordon’s dry gin moringa citrus blend, 43% ethanol, and 200 mg/kg moringa extract, respectively, while Group D (5 animals) did not receive any treatment and was used as negative control. In groups A, B, and C, five animals were sacrificed on the 7th, 14th and 21st day of administration, whereas animals of group D were sacrificed on day 21. The uterus of each rat was harvested, processed and stained with haematoxylin and eosin solution for histological analysis.
Results: Results of the study revealed histological alterations in the uterus of treated animals. Such alterations include adenomatous hyperplasia and cystic hyperplasia.
Conclusion: The oral administration of gordon’s dry gin moringa citrus and moringa extract at 200 mg/kg induced cystic and adenomatous hyperplasia in rat uterus, inferring that both gordon dry gin and moringa might yield antifertility activity.
Assessing Individual Medication Adherence among Chronic Kidney Disease Patients: A Multi-centered Study
Authors: Kadir Tengku Nur Izzati Tengku Abd , Islahudin Farida , Abdullah Muhammad Zulhilmi , Ibrahim Norkasihan , Bing Pau Kiew 
Published: November 2019

Aims: This study aims to identify differences in outcomes of assessing overall versus individual adherence and factors associated with adherence to medication therapy in chronic kidney disease patients.
Study Design: This is a cross-sectional study.
Place and Duration of Study: Nephrology Clinic, Universiti Kebangsaan Malaysia Medical Centre and Ministry of Health Hospitals between June 2018 and June 2019.
Methodology: We included 491 patients (243 men, 248 women); average age of 54.5 (±14.6) years with chronic kidney disease and prescribed at least one medication, using a validated questionnaire.
Results: Patients were prescribed an average of 7.0±2.4 medications. Majority were categorized as adherent (n=404, 82.3%) based on an overall assessment. In contrast, only 27.5% (n=135) were adherent when medications were assessed individually. Based on individual medication assessment, a multivariate logistic regression demonstrated patients aged >55 years were 2.3 times more likely to be adherent toward medicines (P=.001). Those with <3 comorbidities and <7 medications increased the odds of adherence by 2.1 (P=.002) and 2.2 (P=.001) times respectively. Having a drug knowledge score >80% increase the odds of adherence by 8.7 times compared to their counterparts (P<.01).
Conclusion: Potential strategies for targeted management should be developed in order to remove barriers towards medication adherence in chronic kidney disease patients.
Ultra‐Strong Ionogel Adhesives via in situ Microphase Separation
Authors: Huang Yangyu , Ming Xiaoqing , Tang Zhe , Chen Guoqing , Duan Xiaozheng , Zhu He , Zhu Shiping , Zhang Qi 
Published: December 2024

AbstractIonogels hold great promise due to their numerous charges and abundant polarities, which facilitate strong interfacial interactions with substrates. However, the plasticizing effect of ionic liquid weakens their mechanical properties, limiting the adhesive performance of ionogel adhesives. Developing high‐strength ionogel adhesives, therefore, remains a significant challenge. In this work, an exceptional ionogel adhesive is achieved by copolymerizing methyl methacrylate (MMA) and acrylic acid (AA) in 1‐ethyl‐3‐methylimidazolium bis(trifluoromethyl sulfonyl)imide (EMITFSI). The distinct solubilities of the polymers in this ionic liquid result in in situ microphase separation. This novel ionogel exhibits an ultrahigh adhesion strength, with a lap shear strength of 13.41 MPa on glass, surpassing most values reported to date. The remarkable properties of this ionogel are primarily attributed to microphase separation, which enhances adhesion through the arrangement of hydrogen bonds at the interface and improves cohesion by dissipating energy within the bulk. This study offers promising prospects for the design and application of high‐performance ionogel adhesives.
A Wireless Wearable Sensor System Based on a Silver Nanowire‐Decorated Silicon Nanomembrane for Precise and Continuous Hazardous Gas Monitoring
Authors: Shin Jongwoon , Kim Kyubeen , Min In Sik , Sang Mingyu , Lee Ju Young , Hwang Kyuhyun , Kang Yunsung , Kim Jongbaeg , Yu Ki Jun 
Published: December 2024

AbstractWearable wireless gas sensors have attracted enormous interest due to precise, real‐time healthcare and environmental monitoring without temporal and spatial limitations. Among various toxic gases, detecting ammonia is crucial because of its highly hazardous nature and applicability as a noninvasive biomarker for diagnosing health conditions. In this study, silver nanowires‐decorated silicon nanomembrane (AgNW‐SiNM) chemiresistive gas sensor with high selectivity to ammonia is fully integrated with an ultrathin flexible Joule heater and wireless communication system to fabricate wearable wireless real‐time toxic gas monitoring system. The sensor exhibits improved performance to ammonia gas, attributed to heating‐induced changes in adsorption/desorption rates, along with electronic and chemical sensitization facilitated by AgNW decoration. The gas sensing system exhibits stable and high responses of ≈1.83, 1.47, and 1.19 on the ammonia exposure at concentrations of 10, 5, and 1 ppm even under mechanical deformations. The real‐time dynamic response of the sensor is wirelessly transmitted to portable electronics and displayed on the screen. Moreover, the system alerts the users in advance through the integrated haptic interface when exposed to dangerous gas environments for early evacuation. The system paves the way for timely warnings from hazardous gas and more accurate noninvasive medical diagnosis related to respiratory disorders.
Co‐construction of Weak Interlayer Constraint and Sulfur Vacancies Structure in Molybdenum Disulfide to Induce Fast Ammonium Ion Diffusion Kinetics
Authors: Liang Wenlong , Xu Huixin , Yan Junwei , Zeng Yuquan , Zhang Jianli , Hou Guangya , Chen Qiang , Tang Yiping 
Published: December 2024

Abstract2D layered materials, combined with ion intercalation and diffusion storage mechanisms, are among the most promising storage materials for high‐performance rechargeable ion batteries (especially NH4+ storage systems). However, slow interlayer ion diffusion dynamics hinder their development. Most of the research focuses on the diffusion mechanism of interlayer hydrogen bonds, ignoring the special structure and function of the interlayer. In this study, the Mg(H2O)62+ intercalation strategy of MoS2 is proposed and the weak interlayer constraint and sulfur vacancy interlayer structure are co‐constructed. It is found that the intercalation of ions increased the interlayer spacing, effectively increased the ion storage space, and reduced the interlayer constraint of NH4+; Meanwhile, sulfur vacancy reduces the activity and number of NH4+ coordination sites. This special interlayer structure promotes the diffusion kinetics of NH4+. This aspect of concern has been almost ignored in previous studies. This work advances to provide insights and a fundamental understanding of ion diffusion behavior in layered structural features, paving the way for the development of sustainable energy storage systems.
Melt Electrowriting of Elastic Scaffolds Using PEOT‐PBT Multi‐block Copolymer
Authors: Amirsadeghi Armin , Gudeti Pavan Kumar Reddy , Tock Sietse , Koch Marcus , Parisi Daniele , Kamperman Marleen , Włodarczyk‐Biegun Małgorzata Katarzyna 
Published: December 2024

AbstractMelt electrowriting (MEW) is a powerful additive manufacturing technique to produce tissue engineering scaffolds. Despite its strength, it is limited by a small number of processable polymers. Therefore, to broaden the library of materials for MEW, we investigated the printability of poly(ethylene oxide terephthalate)‐poly(butylene terephthalate) (PEOT‐PBT), a thermoplastic elastomer. The effect of different printing parameters and material thermal degradation are studied. It is observed that the material is stable for >60 min at a printing temperature of 195 °C in a nitrogen environment. Next, two types of designs are printed and characterized: mesh‐like and semi‐random scaffolds. For both types of designs, PEOT‐PBT scaffolds reveal a higher yield strain, and lower Young's modulus as compared to control polycaprolactone scaffolds. Biological studies performed using mouse embryonic fibroblasts (NIH‐3T3) show good cell viability and metabolic activity on all print scaffolds. SEM imaging reveals actively migrating cells on PEOT‐PBT mesh scaffolds after 24 h of culture and 98.87% of pore bridging by cells after 28 days of culture. Immunofluorescence staining shows decreased expression of alpha‐smooth muscle actin from day 14 to day 28 in PEOT‐PBT mesh scaffolds. Overall, it is shown that melt electrowritten PEOT‐PBT scaffolds have great potential for soft tissue regeneration.
Functional Hydrogels for Aqueous Zinc‐Based Batteries: Progress and Perspectives
Authors: Mao Lei , Li Guanjie , Zhang Binwei , Wen Kaihua , Wang Cheng , Cai Qinqin , Zhao Xun , Guo Zaiping , Zhang Shilin 
Published: December 2024

AbstractAqueous zinc batteries (AZBs) hold great potential for green grid‐scale energy storage due to their affordability, resource abundance, safety, and environmental friendliness. However, their practical deployment is hindered by challenges related to the electrode, electrolyte, and interface. Functional hydrogels offer a promising solution to address such challenges owing to their broad electrochemical window, tunable structures, and pressure‐responsive mechanical properties. In this review, the key properties that functional hydrogels must possess for advancing AZBs, including mechanical strength, ionic conductivity, swelling behavior, and degradability, from a perspective of the full life cycle of hydrogels in AZBs are summarized. Current modification strategies aimed at enhancing these properties and improving AZB performance are also explored. The challenges and design considerations for integrating functional hydrogels with electrodes and interface are discussed. In the end, the limitations and future directions for hydrogels to bridge the gap between academia and industries for the successful deployment of AZBs are discussed.
Recent Advances in Photoredox/Chromium Dual‐Catalyzed Carbonyl Addition Reactions: A Review
Authors: Xiao Bin , Wu Kangping , Zhang Mianling , Hu Haixiang , Guo Xiaochong 
Published: December 2024

AbstractThe chromium‐catalysed Nozaki‐Hiyama‐Kishi (NHK) reaction is a very dependable technique for alcohol synthesis and is extensively used in the complete synthesis of natural compounds. The majority of these reactions occur via a reductive‐radical‐polar crossover (RRPCO) mechanism, which is crucial for the transformation of reactive radical intermediates. The production of radicals using photoinduced catalytic reactions is now among the most effective approaches. The photoinduced chromium‐catalysed addition reaction to carbonyl compounds is an effective technique for alcohol synthesis that integrates the benefits of photocatalysis with chromium catalysis. Photocatalysis significantly enhances the diversity of radical production, hence broadening the substrate scope in the chromium‐catalysed NHK reaction. This paper primarily examines the photoredox chromium dual‐catalysed carbonyl addition process for alcohol synthesis, including numerous methods for radical generation.
Study on Influence of AC Poling on Bulk Photovoltaic Effect in Pb(Mg1/3Nb2/3)O3‐PbTiO3 Single Crystals
Authors: Balanov Vasilii , Peräntie Jani , Palosaari Jaakko , Yadav Suhas , Bai Yang 
Published: December 2024

AbstractThe bulk photovoltaic effect (BPVE) provides a theory of surpassing the Schockley–Queisser limit. However, improving the BPVE efficiency to a level comparable to that of the semiconductor‐based efficiencies is challenging in practice due to conflicting material design requirements. Previous works have shown that a stacked domain structure in a rhombohedral BiFeO3 ferroelectric epitaxial thin film is able to satisfy the criteria of both a small mean free path for an optimized photocurrent and a large distance between electrodes for an optimized photovoltage. Nevertheless, this hypothesis has remained difficult to verify with other materials due to the complication of domain wall manipulation. This work takes advantage of the recent advances in controlling the domain structure in rhombohedral Pb(Mg1/3Nb2/3)O3‐PbTiO3 (PMN‐PT) single crystals via AC poling. By comparing the photovoltage and photocurrent values after domain manipulations in four types of commercial PMN‐PT samples, this work validates the hypothesis of the stacked domain structure enhancing the BPVE by witnessing a simultaneous increase of over 35% for both the open‐circuit voltage and short‐circuit current from DC to the AC‐poled states under a 405 nm laser illumination. This result paves the way for further improving the BPVE efficiency in ferroelectrics.