bluuebunny/crossref_metadata_2025_split huggingface dataset:
Machine Learning With Feature Domains Elucidates Candidate Drivers of Hospital Readmission Following Spine Surgery in a Large Single-Center Patient Cohort
Authors: Martini Michael L , Neifert Sean N , Oermann Eric K , Gal Jonathan , Rajan Kanaka , Nistal Dominic A , Caridi John M 
Published: April 2020

Abstract

BACKGROUND
Unplanned hospital readmissions constitute a significant cost burden in healthcare. Identifying factors contributing to readmission risk presents opportunities for actionable change to reduce readmission rates.

OBJECTIVE
To combine machine learning classification and feature importance analysis to identify drivers of readmission in a large cohort of spine patients.

METHODS
Cases involving surgical procedures for degenerative spine conditions between 2008 and 2016 were retrospectively reviewed. Of 11 150 cases, 396 patients (3.6%) experienced an unplanned hospital readmission within 30 d of discharge. Over 75 pre-discharge variables were collected and categorized into demographic, perioperative, and resource utilization feature domains. Random forest classification was used to construct predictive models for readmission from feature domains. An ensemble tree-specific method was used to quantify and rank features by relative importance.

RESULTS
In the demographics domain, age and comorbidity burden were the most important features for readmission prediction. Surgical duration and intraoperative oral morphine equivalents were the most important perioperative features, whereas total direct cost and length of stay were most important in the resource utilization domain. In supervised learning experiments for predicting readmission, the demographic domain model performed the best alone, suggesting that demographic features may contribute more to readmission risk than perioperative variables following spine surgery. A predictive model, created using only enriched features showing substantial importance, demonstrated improved predictive capacity compared to previous models, and approached the performance of state-of-the-art, deep-learning models for readmission.

CONCLUSION
This strategy provides insight into global patterns of feature importance and better understanding of drivers of readmissions following spine surgery.
Models or Stars: The Role of Asset Pricing Models and Heuristics in Investor Risk Adjustment
Authors: Evans Richard B , Sun Yang 
Published: April 2020

Abstract
We examine the role of factor models and simple performance heuristics in investor decision-making using Morningstar’s 2002 rating methodology change. Before the change, flows strongly correlated with CAPM alphas. After, when funds are ranked by size and book-to-market groups, flows become more sensitive to 3-factor alphas (FF3). Flows to a matched institutional sample (same managers/strategies) follow FF3 before and after the change but are unrelated to the CAPM. Placebo tests with sector funds and other factor loadings show no effects. Our results imply that improvements in simple performance heuristics can result in more sophisticated risk adjustment by retail investors.
Taper Tantrums: Quantitative Easing, Its Aftermath, and Emerging Market Capital Flows
Authors: Chari Anusha , Dilts Stedman Karlye , Lundblad Christian 
Published: April 2020

Abstract
This paper examines the spillover effects of U.S. unconventional monetary policy (UMP) on emerging market capital flows and asset prices. Affine term structure model estimates show that U.S. monetary policy shocks, identified with high-frequency Treasury futures data, represent revisions to expected short-term yields and term premia, especially during the UMP period. The policy shocks exhibit sizable effects on U.S. holdings of emerging market assets. These effects disproportionately manifest through valuation changes versus physical flows, are more pronounced for equity relative to bond markets, and are asymmetric between the quantitative easing and tapering periods, with flows more important during the unwinding.
Early variation of ultrasound halo sign with treatment and relation with clinical features in patients with giant cell arteritis
Authors: Ponte Cristina , Serafim Ana Sofia , Monti Sara , Fernandes Elisabete , Lee Ellen , Singh Surjeet , Piper Jennifer , Hutchings Andrew , McNally Eugene , Diamantopoulos Andreas P , Dasgupta Bhaskar , Schmidt Wolfgang A , Luqmani Raashid Ahmed 
Published: April 2020

Abstract

Objectives
To compare the ultrasound characteristics with clinical features, final diagnosis and outcome; and to evaluate the halo size following glucocorticoid treatment in patients with newly diagnosed GCA.

Methods
Patients with suspected GCA, recruited from an international cohort, had an ultrasound of temporal (TA) and axillary (AX) arteries performed within 7 days of commencing glucocorticoids. We compared differences in clinical features at disease presentation, after 2 weeks and after 6 months, according to the presence or absence of halo sign. We undertook a cross-sectional analysis of the differences in halo thickness using Pearson’s correlation coefficient (r) and Analysis of Variance (ANOVA).

Results
A total of 345 patients with 6 months follow-up data were included; 226 (65.5%) had a diagnosis of GCA. Jaw claudication and visual symptoms were more frequent in patients with halo sign (P =0.018 and P =0.003, respectively). Physical examination abnormalities were significantly associated with the presence of ipsilateral halo (P &lt;0.05). Stenosis or occlusion on ultrasound failed to contribute to the diagnosis of GCA. During 7 days of glucocorticoid treatment, there was a consistent reduction in halo size in the TA (maximum halo size per patient: r=−0.30, P =0.001; and all halos r=−0.23, P &lt;0.001), but not in the AX (P &gt;0.05). However, the presence of halo at baseline failed to predict future ischaemic events occurring during follow-up.

Conclusion
In newly diagnosed GCA, TA halo is associated with the presence of ischaemic features and its size decreases following glucocorticoid treatment, supporting its early use as a marker of disease activity, in addition to its diagnostic role.
FEASIBILITY OF DISPLAYED EXPOSURE INDEX IN IEC STANDARD FRAMEWORK AS A DOSE OPTIMISATION TOOL FOR DIGITAL RADIOGRAPHY SYSTEMS
Authors: Park Hyemin , Yoon Yongsu , Tanaka Nobukazu , Kim Jungsu , Kim Jungmin , Morishita Junji 
Published: April 2020

Abstract
International Electrotechnical Commission (IEC) established the framework for the use of exposure index (EI) for evaluating the exposure conditions with various digital systems. In this study, we investigated the feasibility of EI, as per the IEC, by comparing the EIs obtained through manual calculated and that displayed on the console of two computed radiography (CR) and digital radiography (DR) systems with radiation beam qualities of RQA3,5,7 and 9. As a result, both two systems indicated an uncertainty of less than 20% for both calculated and displayed EI with all beam qualities except displayed EI obtained by RQA3. However, the displayed EI values were different even under the same exposure conditions because of the characteristics of the imaging receptor materials, such as BaFI or CsI, of two systems. Therefore, when an operator attempts to introduce displayed EI for managing radiation dose, it is essential to understand the characteristics of the digital system.
Training Regimes and Skill Formation in France and Germany An Analysis of Change Between 1970 and 2010
Authors: Elbers Benjamin , Bol Thijs , DiPrete Thomas A 
Published: April 2020

AbstractHow do educational systems prepare workers for the labor market? Stratification research has often made a distinction between two ideal-types: “qualificational spaces,” exemplified by Germany with a focus on vocational education, and “organizational spaces,” exemplified by France with a focus on general education. However, most studies that investigated this distinction did so by focusing only on the size of the vocational sector, not on whether graduates with a vocational degree actually link strongly to the labor market. Moreover, they often studied male workers only, ignoring potential gender differences in how school-to-work linkages are established. In this paper, we map the change in education–occupation linkage in France and Germany between 1970 and 2010 using an approach that can distinguish between changes in rates and changes in the structure of school-to-work linkages. Surprisingly, we find that the German vocational system in 1970 was not, on average, substantially more efficient in allocating graduates to specific occupations than the French system. This finding is a major departure from earlier results, and it shows that the differences between 1970’s France and Germany, on which the qualificational-organizational distinction is based, are smaller than previously assumed. Partly, this is due to the fact that the female labor force was omitted from earlier analyses. We thus show that ignoring the female workforce has consequences for today’s conception of skill formation systems, particularly because a large share of educational expansion is caused by an increase in female enrollment in (higher) education.
“Me Perdía en la Escuela”: Latino Newcomer Youths in the U.S. School System
Authors: Szlyk Hannah Selene , Berger Cardoso Jodi , Barros Lane Liza , Evans Kerri 
Published: April 2020

AbstractUnaccompanied minors, or “newcomer youths,” come to the United States from Mexico and Central America to escape violence and persecution, and to seek financial and academic opportunities. Many newcomer youths arrive with gaps in their formal education attributed to the immigration process and the heterogeneity of their pre-U.S. lives. Once they are enrolled in the U.S. school system, many educators struggle to accommodate the academic needs of these students. Drawing on the framework of social and cultural capital, this article aimed to expand the current knowledge on the experiences of Latino unaccompanied youths in the U.S. school system. A thematic analysis of semistructured interviews with 30 newcomer students and 10 key informants revealed six themes: socialización con los demás compañeros (getting along with the other students); poca confianza (little trust); no sé lo que decían (I do not know what they were saying); it is a hard landing; education, interrupted; and estoy agradecido (I am grateful). The article offers suggestions for school social workers and educators on how to promote academic success, student resilience, and school connectedness for a vulnerable youth population.
Building Competence in Practice with the Polyamorous Community: A Scoping Review
Authors: Katz Mycah Idan Laufer , Graham John R 
Published: April 2020

Abstract
The landscape of relationships, gender, and sexuality continues to change rapidly across the world. This includes recognition of relationship styles such as polyamory, in which individuals have multiple romantic relationships with the knowledge and consent of all involved. In the academic literature on polyamory, social work perspectives are noticeably absent. Thus, a scoping review concerning social work, counseling, and polyamory was conducted to assess knowledge from the last decade and to contribute to the field. The themes that arose were the need for clinicians to examine their biases toward monogamy and polyamory, including perceptions of insecure attachment and a lack of commitment in polyamorous relationships. The literature also recognizes that polyamorous individuals often have fluid identities and sexual orientations. Finally, social workers have a duty to create a safe environment for polyamorous clients because of widespread societal stigma. As social work values client self-determination and examination of societal discourses, the field would benefit from further research into polyamory; this article is just the beginning.
Development and Testing of the Danger Assessment for Law Enforcement (DA-LE)
Authors: Messing Jill Theresa , Campbell Jacquelyn , Dunne Kelly , Dubus Suzanne 
Published: April 2020

AbstractOne-third of women are victimized by intimate partner violence (IPV) in their lifetime; when women are killed, they are often murdered by a previously abusive intimate partner. Risk-informed collaborative interventions, such as domestic violence high risk teams (DVHRTs), use IPV risk assessment to identify and intervene in high-risk IPV cases. This study reports on the development and testing of the Danger Assessment for Law Enforcement (DA-LE), an IPV risk assessment intended for use with DVHRTs. Data were collected through structured telephone interviews from service-seeking survivors of IPV at two time points approximately seven to eight months apart. One sample (n = 570) was used to develop the DA-LE and another (n = 389) was used to test the predictive validity of the instrument using the receiver operating characteristic area under the curve (AUC). The DA-LE predicted near fatal IPV on follow-up with similar or better accuracy than most validated IPV risk assessment instruments (AUC = 0.6864–0.7516). There were no significant differences in predictive validity based on survivor/offender race or ethnicity. The DA-LE has the potential to identify high-risk police-involved IPV cases. Risk-informed collaborative interventions may enhance outcomes for survivors of IPV by holding offenders accountable, increasing help seeking, and reducing future assaults.
Linguistic Complexity of Speech Recognition Test Sentences and Its Influence on Children’s Verbal Repetition Accuracy
Authors: van der Hoek-Snieders Hanneke E.M. , Stegeman Inge , Smit Adriana L. , Rhebergen Koenraad S. 
Published: April 2020

Objectives:
Speech recognition (SR)-tests have been developed for children without considering the linguistic complexity of the sentences used. However, linguistic complexity is hypothesized to influence correct sentence repetition. The aim of this study is to identify lexical and grammatical parameters influencing verbal repetition accuracy of sentences derived from a Dutch SR-test when performed by 6-year-old typically developing children.

Design:
For this observational, cross-sectional study, 40 typically developing children aged 6 were recruited at four primary schools in the Netherlands. All children performed a sentence repetition task derived from an SR-test for adults. The sentence complexity was described beforehand with one lexical parameter, age of acquisition, and four grammatical parameters, specifically sentence length, prepositions, sentence structure, and verb inflection. A multiple logistic regression analysis was performed.

Results:
Sentences with a higher age of acquisition (odds ratio [OR] = 1.59) or greater sentence length (OR = 1.28) had a higher risk of repetition inaccuracy. Sentences including a spatial (OR = 1.25) or other preposition (OR = 1.25) were at increased risk for incorrect repetition, as were complex sentences (OR = 1.69) and sentences in the present perfect (OR = 1.44) or future tense (OR = 2.32).

Conclusions:
The variation in verbal repetition accuracy in 6-year-old children is significantly influenced by both lexical and grammatical parameters. Linguistic complexity is an important factor to take into account when assessing speech intelligibility in children.
Utilization of Telemedicine Virtual Visits in Pediatric Spinal Deformity Patients: A Comparison of Feasibility and Patient Satisfaction at a Large Academic Center
Authors: Sultan Assem A. , Acuña Alexander J. , Samuel Linsen T. , Rabin Jacob M. , Grits Daniel , Gurd David P. , Kuivila Thomas E. , Goodwin Ryan C. 
Published: April 2020

Background:
Telemedicine platforms have been developed to support the convenient delivery of health care services to their patients while maintaining appropriate quality of care. However, it is unclear whether they can be utilized effectively in patients with pediatric spinal deformity (PSD). Therefore, this study aimed to evaluate the feasibility and patient satisfaction associated with virtual visit (VV) utilization in PSD patients in comparison to general pediatric orthopaedic indications.

Methods:
Of the 482 VVs offered to pediatric orthopaedic patients at a large academic health care system between January 1, 2017, and December 31, 2018, a total of 189 VVs conducted by board-certified orthopaedic surgeons were included in the final analysis. Patient satisfaction scores were collected at the end of each VV by patient and parent rankings of the surgeon and the telemedicine service. Data on patients, visits, and connectivity sessions characteristics were collected and statistically compared between PSD visits (n=33) versus those conducted for general pediatric orthopaedic indications (n=156).

Results:
Although PSD patients were older (15±3.7 vs. 12±4.7 y; P<0.01), mostly female (76% vs. 47%, P=0.003), and had longer VVs (8±4.6 vs. 5±3.6 min; P=0.003) versus their general pediatric orthopaedic counterparts, they demonstrated similarly high satisfaction scores for surgeon performance (5±0 vs. 4.8±0.1 points; P=0.08) and overall satisfaction (3±2.4 vs. 3.5±2.1; P=0.23). Approximately 80% of all VVs were conducted over mobile devices. Wait time was substantially less for PSD VVs relative to subsequent office visits (13±10 vs. 41±30 min; P<0.001).

Conclusions:
Our analysis found that telemedicine VVs provided a convenient alternative to traditional in-office visits for PSD patients. Specifically, we found that PSD patients received faster care with comparable satisfaction. The findings of our present analysis should encourage health care systems to continually evaluate and implement telehealth platforms to improve both the accessibility and appropriate quality of care.

Level of Evidence:
Level IV.
Doxorubicin and Olaratumab Versus Doxorubicin, Ifosfamide, and Mesna for Treatment of Advanced Soft Tissue Sarcomas
Authors: Hammer Kathryn J. , Copeland Vanessa C. , Loggers Elizabeth T. , Pollack Seth M. , Wagner Michael J. , Cranmer Lee D. 
Published: April 2020

Objective:
We compared the outcomes in soft tissue sarcoma (STS) treated with olaratumab and doxorubicin (OD) versus doxorubicin, ifosfamide, and mesna (AIM) to assess whether OD could supersede AIM in STS therapy.

Methods:
A single-institution, retrospective study of STS treated for advanced disease with OD or AIM in 2013 to 2017 was conducted. Demographic and clinical parameters were compared by Fisher’s exact test. Kaplan-Meier and Cox analyses examined progression-free survival (PFS) and overall survival (OS). Adverse events were compared.

Results:
Thirty patients (13 OD, 17 AIM) were included. OD was administered more commonly after first-line therapy (54% OD vs. 6% AIM, P=0.0005). The 2 groups did not differ in other parameters. Median OS [OD: 14.2 mo, 95% confidence interval (CI): 7.1-not reached; AIM 19.9 mo, 95% CI 9.5-35.5; hazard ratio: 0.99, 95% CI: 0.38-2.59, P=0.99] and PFS (OD: 2.6 mo, 95% CI: 1.3-7; AIM 6.4 mo, 95% CI: 1.5-14.5; hazard ratio: 0.57, 95% CI: 0.26-1.24, P=0.16) were not statistically different, although median values favored AIM. Grade 3 to 4 neutropenia, but not febrile neutropenia, was more frequent with OD.

Conclusions:
OD and AIM did not differ with respect to either OS or PFS. Although this study’s size initially appeared the most likely explanation, lack of significant activity of olaratumab was subsequently reported in the phase III trial of OD. Our results suggest that future conditional oncology drug approvals should be accompanied by mandated registries to monitor outcomes of patients treated after conditional approval, but before full approval.
Recurrence Rates Following Excision of Hidradenitis Suppurativa: A Systematic Review and Meta-analysis
Authors: Ovadja Zachri N. , Jacobs Wilco , Zugaj Mislav , van der Horst Chantal M.A.M. , Lapid Oren 
Published: April 2020

BACKGROUND
Surgery is considered to be the best treatment for recurrent hidradenitis suppurativa (HS). Varying recurrence rates have been reported in the literature.

OBJECTIVE
To provide an up-to-date systematic review of the complete literature for different excision strategies and their recurrence rates in HS.

METHODS
A systematic literature search of the complete available literature and a meta-analysis of proportions were performed on the included studies.

RESULTS
Of a total of 1,593 retrieved articles, 125 were included in the analysis. Most of these studies were retrospective with 8 prospective analyses and one randomized controlled trial (RCT). The techniques described were divided into partial excision (PE) and wide excision (WE), described in 33 and 97 included studies, respectively. The average estimated recurrences were 26.0% (95% confidence interval [CI], 16.0%–37.0%) for PE and 5.0% (95% CI, 3.0%–9.0%) for WE (p < .01). Female sex (p = .016) and HS caudal of the umbilicus (p = .001) were significantly associated with the overall recurrence rate. Quality of evidence was poor, and the reporting of results was mostly heterogeneous.

CONCLUSION
This systematic review showed higher recurrence rates when it was not intended to resect affected HS tissue with a radical margin. There is a need for more RCT's and uniformly reported treatment outcomes.
The Epidemiology of Extrapulmonary Non-tuberculous Mycobacterial Infection in a Pediatric Population
Authors: Aliano Danielle , Thomson Rachel 
Published: April 2020

Background:
Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and a well-known cause of lymphadenitis, skin and soft tissue infections. The aim of this study was to evaluate the epidemiology of extrapulmonary pediatric NTM infections occurring from 2000 to 2017 in Queensland, Australia.

Methods:
All cases of NTM and TB are notifiable under the Queensland Public Health Act (2005) and associated regulations (2005). Data from 2000 to 2017 inclusive was collected from the Notifiable Conditions Database, a laboratory based notification system that covers private and public laboratory systems. Pediatric population demographic data were obtained from the Australian Bureau of Statistics by researching the number of children 0–14 years of age in Queensland from 2000 to 2017; both annual and averaged population was determined. The statistical software SPSS and Tableau was used for analysis.

Results:
The mean age of diagnosis was 2.5 years with a majority of the cohort being women. Mycobacterium avium was the most commonly diagnosed pathogen. Geographic regions with the highest numbers of cases were predominantly tropical and coastal areas. M. haemophilum emerged as a more common pathogen from 2011 following a period of major flooding.

Conclusion:
Characteristics of the cohort of children susceptible to NTM disease appears consistent with previous reports. However, changes in the epidemiology of NTM infection (such as incidence, species, and geographic distribution) in children may be linked to environmental and weather factors.
Risk Stratification and Personal Protective Equipment Use in Pediatric Endoscopy During the Coronavirus Disease 2019 Outbreak
Authors: Say Daphne S. , de Lorimier Arthur , Lammers Cathleen R. , Natale JoAnne , Lakshminrusimha Satyan , Wiedeman Jean , Partridge Elizabeth 
Published: April 2020

ABSTRACTSARS‐CoV‐2, the novel coronavirus causing coronavirus disease 2019 (COVID‐19), is now a global pandemic. Human‐to‐human transmission has been documented to occur through respiratory secretions, feces, aerosols, and contaminated environmental surfaces. Pediatric patients present a unique challenge as they may have minimal symptoms and yet transmit disease. Endoscopists face risk for infection with viruses like SARS‐CoV‐2, as the aerosol generating nature of endoscopy diffuses respiratory disease that can be spread via an airborne and droplet route. We describe our center's methodology for pediatric patient risk stratification to facilitate responsible use of endoscopic resources during this crisis. We also describe our recommendations for use of personal protective equipment by endoscopists, with the goal of ensuring the safety of ourselves, our anesthesiology and endoscopy staff, and our patients.