bluuebunny/crossref_metadata_2025_split huggingface dataset:
Managers' risk perception and the adoption of sustainable consumption strategies in the hospitality sector: the moderating role of stakeholder salience attributes
Authors: ElShafei Rasha 
Published: July 2020

PurposeThis study investigates the relationship between managers' risk perception and the adoption of sustainable water consumption strategies and analyzes the moderating effect of stakeholders' salience attributes on this relationship.Design/methodology/approachA conceptual framework that builds on the stakeholder theory was developed to illustrate the direct and moderating role of the study variables. The derived hypotheses were tested quantitatively using multiple regression analysis.FindingsResults indicate that managers' risk perception and the three stakeholder salience attributes were significantly associated with sustainable water consumption strategies, and that the legitimacy attribute was a successful moderator between the study variables.Research limitations/implicationsThe limited ability to generalize results as the study is centered on the hospitality sector. Although the results were comparable to other studies, it is not possible to claim that the findings represent the views of the majority of managers in different industry sectors.Practical implicationsThe research highlights to managers in the hospitality sector, the significant influence of risk perception and stakeholder salience attributes on the adoption of sustainable water consumption strategies.Social implicationsThe research revealed that media, consumers and competitors are powerful, legitimate and urgent stakeholders, respectively. Therefore, the research findings will guide policymakers and nonprofit organizations to support those stakeholders in order to strengthen their power, legitimacy and urgency attributes.Originality/valueAlthough it has been claimed that risk perception has the potential to influence sustainable consumption of natural resources, few studies empirically investigated the association of risk perception of a specific environmental threat with responsible consumption. Moreover, even though there is general agreement in the literature that the adoption of sustainable water consumption strategies is shaped by the degree to which stakeholders exercise their salience attributes, studies that empirically examine the influence of these attributes within the hospitality sector are lacking. Therefore, this study fills a gap in the current literature by empirically examining the influence of managers' risk perception and stakeholder's salience attributes on firms' adoption of sustainable consumption strategies.
Scoundrel or freedom fighter? Creating historical empathy inquiries
Authors: Muetterties Carly C. , Bronstein Erin A. 
Published: July 2020

PurposeThis work explores the creation and purposes of an inquiry about Emilio Aguinaldo, a Filipino revolutionary and sometimes United States ally, as a means to discuss the value of both inquiry and historical empathy in bridging history instruction and civic life. Though history is often identified as a means to foster democratic dispositions, learning can often feel disconnected from students' lived experiences, let alone directly connect to their out-of-classroom circumstances. Teaching with historical empathy allows students to affectively engage with content, resulting in complex reasoning and content acquisition.Design/methodology/approachThe authors explain an original inquiry that uses the Inquiry Design Model (IDM) and historical empathy to help students complicate Emilio Aguinaldo and his legacy. By combining historical empathy and the inquiry model, the authors structured their work for practitioner use but also as a way to draw on rarely emphasized content in US or World history courses.FindingsIn using this model, students will be able to apply their learning in a civic engagement task related to modern questions of US geopolitics.Originality/valueThe authors offer and explore the process of an original inquiry as a way to help practitioners and scholars consider how to create other such rigorous opportunities for students to practice global citizenship.
Clinical characteristics, trichoscopy, histopathology and treatment outcomes of frontal fibrosing alopecia in an Asian population: A retro‐prospective cohort study
Authors: Panchaprateep Ratchathorn , Ruxrungtham Pariya , Chancheewa Bussabong , Asawanonda Pravit 
Published: July 2020

AbstractFrontal fibrosing alopecia (FFA) is a distinctive lymphocytic scarring alopecia with rapid increase in prevalence. Most FFA series are retrospectively reported from Caucasians with only few from Asians. The objective of this study was to characterize the clinical, trichoscopic and histopathological findings as well as treatment outcomes. This was a retro‐prospective cohort study of patients diagnosed with FFA from 1 January 2010 to 1 November 2019. All patients were asked to present for re‐examination. Clinical, trichoscopic, histopathological and laboratory data were recorded. A questionnaire was used to investigate hair care, hairstyle and facial skin care compared with age‐matched normal controls. Multivariate analysis was performed in order to clarify factors associated with severity. All 58 FFA patients were female, of whom 27.6% were premenopausal, 37.7% had a history of surgical menopause, 13.8% had thyroid diseases, 69% had eyebrow loss and 32.8% facial papules. On physical examination, 10.3% showed linear pattern, 46.6% diffuse pattern and 43.1% pseudo‐fringe sign. Concomitant lichen planopilaris was found in 25.9%, lichen planus pigmentosus in 24.1% and female pattern hair loss in 48.3%. The most common trichoscopic characteristics in the frontal hairline were lack of follicular ostia (91.4%), perifollicular scales (79.3%) and perifollicular erythema (63.8%). Up to 90% of patients reported FFA as improved or stable after receiving antiandrogen (finasteride or dutasteride) or antimalarial with topical treatment. Multivariate analyses revealed that facial lentiginous macules and trichoscopic perifollicular erythema at the frontal area were FFA severity‐associated factors. “Front puff” Thai hairstyle was associated with FFA, while sunscreens and other cosmetic products were not. In conclusion, diffuse and pseudo‐fringe sign pattern are common in Asian FFA. The most common autoimmune systemic comorbidity is thyroid disease, while common concomitant dermatological diseases are female pattern hair loss, lichen planopilaris and lichen planus pigmentosus. Antiandrogens or antimalarial plus topical treatment are the most useful therapy.
Interactive persistent effects of past land‐cover and its trajectory on tropical freshwater biodiversity
Authors: Santos Edineusa P. , Wagner Helene H. , Ferraz Sílvio F. B. , Siqueira Tadeu 
Published: July 2020

Abstract

Evidence indicating that ecological communities show delayed responses to environmental change has raised the need to better understand the effects of landscape history on biodiversity.

We investigated how freshwater biodiversity is related to both recent and past land use change in tropical river catchments. More specifically, we analysed the relationship between biodiversity and change in forest cover that occurred across five decades, including landscape trajectories of forest gain and loss.

The abundance of stream insects showed a more delayed response to landscape change than rarefied richness, whereas the Tsallis diversity index was not related to past forest cover. However, both alpha diversity and local abundance were related to mean forest cover across the five decades when conditioned by the trajectory of change. We found a negative relationship between the historical mean of forest cover and community descriptors in streams embedded in landscapes on a trajectory of forest loss, but a positive relationship in landscapes on a trajectory of forest gain.

We provide the first evidence of delayed responses of tropical freshwater insect communities to landscape history and suggest that the magnitude of change in forest cover, mediated by its trajectory, is a major driver of delayed responses. We show that a trajectory of forest loss might result in both immediate loss of species and a set of species doomed for future extinction.

Synthesis and applications. Delayed responses of multispecies communities to past landscape changes depend on their extent, frequency and intensity. Our findings indicate that, beyond the relative amount of forest cover within river catchments, the magnitude of change in forest cover mediated by its historical trajectory can be a major driver of delayed responses in stream communities. We suggest that, if biodiversity conservation is the main aim, stream restoration should be prioritized in catchments with higher forest cover, as even under a forest gain trajectory, stream communities continue responding to past landscape changes depending on how widespread and intensive changes were.
Materialities in supported housing for people with mental health problems: a blurry picture of the tenants
Authors: Friesinger Jan G. , Topor Alain , Bøe Tore Dag , Larsen Inger Beate 
Published: July 2020

AbstractOur daily lives and sense of self are partly formed by material surroundings that are often taken for granted. This materiality is also important for people with mental health problems living in supported housing with surroundings consisting of different healthcare services, neighbourhoods, buildings or furniture. In this study, we explored how understandings of tenants are expressed in the materialities of supported housing. We conducted ethnographic fieldwork in seven different supported accommodations in Norway and analysed the resultant field notes, interviews, photographs and documents using Situational Analysis. The analysis showed that supported housing materialities expressed a blurry picture comprising widening and narrowing understandings of tenants, both by others and by themselves. Widening understandings concerned how tenants were living their lives in their own ways in private rooms while maintaining a social life in common areas. Narrowing understandings pertained to understand the tenants based solely on their diagnosis and need for care and control in hospital‐like buildings. The following discussion focusses on the ideas that underlie narrowing materialities and on the importance of striving for atmospheres that entail a sense of belonging.
Physiological role of plasma and its components and the clinical implications of different methods of apheresis: A narrative review
Authors: Ahmadpoor Pedram , Aglae Cedric , Cariou Sylvain , Pambrun Emilie , Renaud Sophie , Garo Florian , Darmon Ruben , Schultz Celine , Prelipcean Camelia , Reboul Pascal , Moranne Olivier 
Published: July 2020

AbstractNowadays, therapeutic plasmapheresis (TP) is accepted as part of the treatment for specific groups of diseases. The availability of different methods, including double filtration and adsorption, increases selectivity for the removal of substances. However, the use of these techniques requires a thorough understanding of the characteristics and components of plasma. By considering pivotal papers from several databases, the aim of this narrative review is to describe the characteristics of plasma related to apheresis techniques. We have tried to cover the clinical implications including physiology, estimation of plasma volume, viscosity, and a description of its components including the size, volume of distribution, and half‐lives of the different substances to be removed or maintained depending on the clinical situation and applied apheresis technique. Applying this knowledge will help us to choose the right method and dosage and improve the efficacy of the procedure by preventing or addressing any complications.
SEVA 3.1: enabling interoperability of DNA assembly among the SEVA, BioBricks and Type IIS restriction enzyme standards
Authors: Damalas Stamatios G. , Batianis Christos , Martin‐Pascual Maria , de Lorenzo Victor , Martins dos Santos Vitor A. P. 
Published: July 2020

SummaryRobust synthetic biology applications rely heavily on the design and assembly of DNA parts with specific functionalities based on engineering principles. However, the assembly standards adopted by different communities vary considerably, thus limiting the interoperability of parts, vectors and methods. We hereby introduce the SEVA 3.1 platform consisting of the SEVA 3.1 vectors and the Golden Gate‐based ‘SevaBrick Assembly’. This platform enables the convergence of standard processes between the SEVA platform, the BioBricks and the Type IIs‐mediated DNA assemblies to reduce complexity and optimize compatibility between parts and methods. It features a wide library of cloning vectors along with a core set of standard SevaBrick primers that allow multipart assembly and exchange of short functional genetic elements (promoters, RBSs) with minimal cloning and design effort. As proof of concept, we constructed, among others, multiple sfGFP expression vectors under the control of eight RBSs, eight promoters and four origins of replication as well as an inducible four‐gene operon expressing the biosynthetic genes for the black pigment proviolacein. To demonstrate the interoperability of the SEVA 3.1 vectors, all constructs were characterized in both Pseudomonas putida and Escherichia coli. In summary, the SEVA 3.1 platform optimizes compatibility and modularity of inserts and backbones with a cost‐ and time‐friendly DNA assembly method, substantially expanding the toolbox for successful synthetic biology applications in Gram‐negative bacteria.
A decade of epigenetic change in aging twins: Genetic and environmental contributions to longitudinal DNA methylation
Authors: Reynolds Chandra A. , Tan Qihua , Munoz Elizabeth , Jylhävä Juulia , Hjelmborg Jacob , Christiansen Lene , Hägg Sara , Pedersen Nancy L. 
Published: July 2020

AbstractBackgroundEpigenetic changes may result from the interplay of environmental exposures and genetic influences and contribute to differences in age‐related disease, disability, and mortality risk. However, the etiologies contributing to stability and change in DNA methylation have rarely been examined longitudinally.MethodsWe considered DNA methylation in whole blood leukocyte DNA across a 10‐year span in two samples of same‐sex aging twins: (a) Swedish Adoption Twin Study of Aging (SATSA; N = 53 pairs, 53% female; 62.9 and 72.5 years, SD = 7.2 years); (b) Longitudinal Study of Aging Danish Twins (LSADT; N = 43 pairs, 72% female, 76.2 and 86.1 years, SD=1.8 years). Joint biometrical analyses were conducted on 358,836 methylation probes in common. Bivariate twin models were fitted, adjusting for age, sex, and country.ResultsOverall, results suggest genetic contributions to DNA methylation across 358,836 sites tended to be small and lessen across 10 years (broad heritability M = 23.8% and 18.0%) but contributed to stability across time while person‐specific factors explained emergent influences across the decade. Aging‐specific sites identified from prior EWAS and methylation age clocks were more heritable than background sites. The 5037 sites that showed the greatest heritable/familial–environmental influences (p < 1E−07) were enriched for immune and inflammation pathways while 2020 low stability sites showed enrichment in stress‐related pathways.ConclusionsAcross time, stability in methylation is primarily due to genetic contributions, while novel experiences and exposures contribute to methylation differences. Elevated genetic contributions at age‐related methylation sites suggest that adaptions to aging and senescence may be differentially impacted by genetic background.
Alcohol use disorder and the liver
Authors: Buchanan Ryan , Sinclair Julia M. A. 
Published: July 2020

AbstractAlcohol use disorders (AUD) cause a range of physical harms, but the major cause of alcohol‐related mortality is alcohol‐related liver disease (ALD), in some countries accounting for almost 90% of alcohol‐related deaths. The risk of ALD has an exponential relationship with increasing alcohol consumption, but is also associated with genetic factors, other life‐style factors and social deprivation. ALD includes a spectrum of progressive pathology, from liver steatosis to fibrosis and liver cirrhosis. There are no specific treatments for liver cirrhosis, but abstinence from alcohol is key to limit progression of the disease. Over time, cirrhosis can progress (often silently) to decompensated cirrhosis and hepatocellular carcinoma (HCC). Liver transplantation may be suitable for patients with decompensated liver cirrhosis and may also be used as a curative intervention for HCC, but only for a few selected patients, and complete abstinence is a prerequisite. Patients with AUD are also at risk of developing alcoholic hepatitis, which has a high mortality and limited evidence for effective therapies. There is a strong evidence base for the effectiveness of psychosocial and pharmacological interventions for AUD, but very few of these have been trialled in patients with comorbid ALD. Integrated specialist alcohol and hepatology collaborations are required to develop interventions and pathways for patients with ALD and ongoing AUD.
Combined association of massive choroidal and optic nerve invasion as a prognostic relevance in primary retinoblastoma: A 10‐year study
Authors: Kashyap Seema , Singh Lata , Kumar Nikhil , Singh Mithalesh Kumar , Pushker Neelam , Bakhshi Sameer , Sen Seema , Lomi Neiwete , Meel Rachna , Chawla Bhavna 
Published: July 2020

AbstractPurposeTo determine the significance of both massive choroidal invasion and optic nerve invasion (retrolaminar [(RL]+cut end [CE]) as a criterion for classifying high metastatic potential retinoblastoma and their relationship with other known histopathological high‐risk features.MethodsA retrospective review of 650 eyes diagnosed as retinoblastoma over a 10‐year period. In our study, there is male predominance and a higher percentage of the poorly differentiated tumors. The age of most of the patients ranges from 1 month to 8 years with a median age of 2 years.ResultsThere were 24% of eyes with massive choroidal invasion and 18% of eyes with optic nerve invasion up to the cut end. On performing Cox‐proportional hazard analysis, it was found that massive choroidal invasion in association with optic nerve invasion up to the cut end was an independent prognostic parameter. On Kaplan‐Meier analysis, overall survival had reduced in patients having both massive choroidal invasion and an optic nerve cut end invasion along with orbital invasion (P < .05).ConclusionThe presence of massive choroidal invasion in association with optic nerve cut end invasion (RL+CE) could be used as a better prognostic predictor in assessing retinoblastoma patients with high metastatic potential and need to be kept for longer follow up.
Clinical molecular genetics evaluation in women with reproductive failures
Authors: Bilal Mahmood Y. , Katara Gajendra , Dambaeva Svetlana , Kwak‐Kim Joanne , Gilman‐Sachs Alice , Beaman Kenneth D. 
Published: July 2020

AbstractMolecular diagnostics is a rapidly growing branch of the clinical laboratory and has accelerated the advance of personalized medicine in the fields of pharmacogenomics, pharmacogenetics, and nutrigenomics. The versatility of molecular biology allows it to be effective in several medical fields that include reproduction, immunogenetics, and virology. Implementation of molecular and sequencing technology in reproductive medicine can add another layer of understanding to better define the causes behind infertility and recurrent reproductive loss. In the following, we examine current molecular methods for probing factors behind reproductive pregnancy loss including reverse transcription polymerase chain reaction and next generation sequencing (NGS). We review several current and potential genetic (DNA) and transcriptional (RNA)‐based parameters in women with infertility that can be significant in diagnosis and treatment. These molecular factors can be inferred either from genomic DNA or RNA locally within the endometrium. Furthermore, we consider infection‐based abnormalities such as human herpesvirus‐6 and severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2). Finally, we present future directions as well as data demonstrating the potential role of human endogenous retroviruses in pregnancy loss. We hope these discussions will assist the clinician in delineating some of the intricate molecular factors that can contribute to infertility and recurrent reproductive failures.
How Government Credibility and Social Morality Work in a Public Health Emergency. A Study of Public Quarantine Willingness in COVID‐19
Authors: Xiang Pengcheng , Guo Jin , Liu Qiqi 
Published: July 2020

AbstractThis study explores the relationships among the variables: willingness to quarantine, perception of the epidemic, willingness to do outdoor activities, government credibility, and public morality. To understand these relationships, it integrates theories including epidemic prevention and control, government credibility, public morality, and social network systems. Structural equation modeling (SEM) with bootstrapping estimation was conducted using data calculated from 368 healthy citizens who are quarantining at home due to COVID‐19 in Chinese cities that have launched a first‐level primary public safety incident response. The results show that residents’ perception of the epidemic has a positive effect on their willingness to quarantine, and willingness to do outdoor activities has a negative effect. Moreover, government credibility and public morality have a mediating effect on the relationship between the perception of epidemic and willingness to quarantine. What is more, government credibility has a moderating effect on the relationship between willingness to do outdoor activities and willingness to quarantine. We discuss the implications of these results for beating future epidemics that may break out.
Do cultural differences affect users’ e‐learning adoption? A meta‐analysis
Authors: Zhao Yang , Wang Ning , Li Yixuan , Zhou Ruoxin , Li Shuangshuang 
Published: July 2020

AbstractThe great advantages of e‐learning have been recognized, and efforts have been made to promote e‐learning adoption. Despite valuable research achievements from technology adoption, previous studies built their models from different perspectives. In this study, to offer a comprehensive research model on e‐learning adoption, we integrated these models (ie, TAM, TPB and IDT) and included culture as a moderator. Based on 45 relevant empirical research, this study conducted a meta‐analysis to explore key determinants of users’ attitude and behavioral intention to adopt e‐learning. Combined with traditional technology acceptance theories and innovation diffusion theory, we developed a comprehensive model and explored the moderating role of culture. The results indicate that this integrated technology acceptance model can be applied to better understand e‐learning adoption. The moderator analysis shows that the influence of subjective norms and self‐efficacy on users’ behavior intention is more salient in the collectivistic culture, whereas perceived usefulness is more important for online learners in an individualistic culture.