bluuebunny/crossref_metadata_2025_split huggingface dataset:
An observational study to evaluate the prescription pattern of analgesics used in the perioperative period in a tertiary care hospital
Authors: Joshi Shirish , Shetty Yashashri , Panchal Roshni , Patankar Panini , Salgaonkar Sweta , Rawat Rishabh , Natu Anuya 
Published: May 2020

Background and Aims:
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage. There are limited observational prescription pattern studies of analgesics in perioperative period in tertiary care hospitals for which this study was carried out in orthopedic, general surgery, and plastic surgery departments. The primary aim was to study the prescription pattern of analgesics in the perioperative period with the secondary aim to study the specific use of opioids and pain relief using the Visual Analog Scale (VAS).

Methods:
A total of 250, 250, and 100 patients were taken from orthopedic, general surgery, and plastic surgery departments, respectively. The analgesics commonly used in preoperative, intraoperative, and postoperative period were observed. The use of opioids in the perioperative period, the number of fixed drug combinations used, the number of generic drug prescription, and pain relief postoperatively were also observed. The analysis was done using descriptive statistics.

Results:
Total analgesics prescribed were 1168, 117, and 369 in orthopedic, general surgery, and plastic surgery departments, respectively, and were maximum in the intraoperative period. Most commonly used analgesic in the preoperative and postoperative period was paracetamol and that in intraoperative period was fentanyl. Nonsteroidal anti-inflammatory drugs (NSAIDs) were mainly prescribed by the general surgery department in postoperative period. The amount of pain in postoperative period after treatment with analgesics was mild to moderate as per the VAS.

Conclusion:
This study revealed that in preoperative and postoperative period, the most common analgesic used is paracetamol. In the intraoperative period, maximum patients received fentanyl. Diclofenac is an established NSAID used in the management of acute and chronic pain states. In our study, we found that the usage of paracetamol was more than NSAIDs and the usage of opioid was maximum during intraoperative period.
ადამიანური რესურსების მართვის ტენდენციები, გამოწვევები და ორიენტირები
Authors: Gulua Ekaterine 
Published: May 2020

ეკატერინე გულუა
ეკონომიკის დოქტორი,
ივანე ჯავახიშვილის სახელობის თბილისის
სახელმწიფო უნივერსიტეტის ასისტენტ-პროფესორი
საქართველო, თბილისი
E-mail: ekaterine.gulua@tsu.ge
http://orcid.org/0000-0001-9484-093X

მოკლე აღწერა
გლობალური პროცესებითა და ცვლილებებით გამოწ­ვეუ­ლი ტენდენციები ეკონომიკური სუბიექტების მენეჯ­მენ­ტი­სთ­ვის ახალ შესაძლებლობებთან ერთად, წარმოქმნილი გამო­წ­ვ­ევების გათვალისწინების აუცილებლობას ქმნის. ნაშრომში გა­ნ­ხილულია ადამიანური რესურსების მართვის ძირითადი პა­რადიგმები, მიმდინარე გლობალური ტენდენციები და გამ­ო­წ­ვევები. შესაძლოა, კოვიდ 19-ის გავრცელებით გამოწვეული გლ­ო­ბალური პანდემიის პირობებში მომავლის პროგ­ნო­ზი­რე­ბა საკმაოდ რთულია, თუმცა ცხადია, ბევრი კომპანიისთვის გა­და­რჩენის ერთადერთი გზა პროცესების გაციფრულებაზე გა­დის. არსებული ქაოსური გარემო ადამიანური რესურსების მე­ნე­ჯერების მხრიდან მოითხოვს სწრაფ ადაპტირებას ახალ გა­მო­წვევებთან, როგორიცაა: თანამშრომლებთან ონლაინ ურ­თი­ერ­თობები, პროცესების ონლაინ წარმართვა, კონტროლის ახა­ლი მექანიზმები, თანამშრომელთა დათხოვნის, შენარჩუნების და შერჩევის საჭიროებებთან გამკლავება. ადამიანებში ვირ­ტუ­ა­ლური ურთიერთობების საფუძველზე ისეთი ტალანტების დე­კოდირება, როგორიცაა: ადაპტაციის უნარი, ლატერალური აზ­როვნება, სისხარტე. ეს არის დრო, როდესაც განსაკუთრებით ფა­სეული გახდა მცოდნე და ცვალებად გარემოსთან ადაპ­ტი­რე­ბა­დი ადამიანური რესურსები. როგორც არასდროს აქტ­უა­ლუ­რია ორგანიზაციის შედეგებში წვლილის პროპორციული სტი­მუ­ლირების მექანიზმების ამოქმედება. ნაშრომში შეს­წა­ვ­ლი­ლია საქართველოს მდგომარეობა გლობალური ინდ­იკა­ტო­რე-ბის რაკურსით, აგრეთვე ადამიანური რესურსების მართვის პრ­ი­­ორიტეტები და ორიენტირები, რომელთა გათვალისწინება მნი­შვნელოვან როლს შეასრულებს ორგანიზაციების კონ­კუ­რენ­ტუნარიან ოპერირებაში. ნაშრომი აგრეთვე ეფუძნება ავტ­ო­რ­ის ადრეულ კვლევებს.
საკვანძო სიტყვები: ადამიანური რესურსების მენეჯემენტის (არმ) ტენდენციები, არმ-ის გამოწვევები; არმ-ის განვითარების ორიენტირები, არმ-ის სტრატეგიები გლობალურ, მიკრო და მაკრო დონეზე.
Measurements of the water balance components of a large green roof in the greater Paris area
Authors: Versini Pierre-Antoine , Stanic Filip , Gires Auguste , Schertzer Daniel , Tchiguirinskaia Ioulia 
Published: May 2020

Abstract. The Blue Green Wave of Champs-sur-Marne (France)
represents the largest green roof (1 ha) of the greater Paris area. The
Hydrology, Meteorology and Complexity lab of École des Ponts ParisTech has
chosen to convert this architectural building into a full-scale monitoring
site devoted to studying the performance of green infrastructures in
storm-water management. For this purpose, the relevant components of the
water balance during a rainfall event have been monitored: rainfall, water
content in the substrate, and the discharge flowing out of the
infrastructure. Data provided by adapted measurement sensors were collected
during 78 d between February and May 2018. The related raw data and a
Python program transforming them into hydrological quantities and providing
some preliminary elements of analysis have been made available. These
measurements are useful to better understand the hydrological processes
(infiltration and retention) conducting green roof performance and their
spatial variability due to substrate heterogeneity.
The data set is available here: https://doi.org/10.5281/zenodo.3687775 (Versini et al., 2019b).
Documenting numerical experiments in support of the Coupled Model Intercomparison Project Phase 6 (CMIP6)
Authors: Pascoe Charlotte , Lawrence Bryan N. , Guilyardi Eric , Juckes Martin , Taylor Karl E. 
Published: May 2020

Abstract. Numerical simulation, and in particular simulation of the earth system, relies on contributions from diverse communities, from those who develop models to those involved in devising, executing, and analysing numerical experiments.
Often these people work in different institutions and may be working with significant separation in time (particularly analysts, who may be working on data produced years earlier), and they typically communicate via published information (whether journal papers, technical notes, or websites).
The complexity of the models, experiments, and methodologies, along with the diversity (and sometimes inexact nature) of information sources, can easily lead to misinterpretation of what was actually intended or done.
In this paper we introduce a taxonomy of terms for more clearly defining numerical experiments, put it in the context of previous work on experimental ontologies, and describe how we have used it to document the experiments of the sixth phase for the Coupled Model Intercomparison Project (CMIP6).
We describe how, through iteration with a range of CMIP6 stakeholders, we rationalized multiple sources of information and improved the clarity of experimental definitions.
We demonstrate how this process has added value to CMIP6 itself by (a) helping those devising experiments to be clear about their goals and their implementation, (b) making it easier for those executing experiments to know what is intended, (c) exposing interrelationships between experiments, and (d) making it clearer for third parties (data users) to understand the CMIP6 experiments.
We conclude with some lessons learnt and how these may be applied to future CMIP phases as well as other modelling campaigns.
Human Sacrifice, Nuns, and Gender-Bent Kings: The Effect of Religious Change on Gender Presentation in Early Modern Adaptations ofIphigenia among the Taurians
Authors: Wolfe Rachel M. E. 
Published: May 2020

AbstractEuiripides's tragedy Iphigenia among the Taurians has been considered famously difficult to adapt, in no small part because its primary theme is the establishment of a long-dead ancient Greek religious cult. This article examines the substantial adaptive changes that early modern adaptors employed to make this pagan story stageable in Christian Europe, with a particular focus on gender. Utilizing the case studies of a neoclassical French popular success (De La Grange-Chancel's Oreste et Pilade) and the Lockean English adaptation it spawned in turn (Dennis's Iphigenia: A Tragedy), “Human Sacrifice, Nuns, and Gender-Bent Kings” tracks this story's evolution from religious to political to colonial in its corresponding journey from Pagan to Catholic to Protestant Humanist, while exploring how each of these incarnations depends on alterations of gender presentation for its thematic coherence. In showing the drastic changes that were made to characters' gender presentations, and how those gender presentations underpin religious doctrine in each context, this paper demonstrates the strong links between religious faith and constructions of gender in the process of cross-cultural adaptation.
Awareness Regarding Key Aspects of the Sickle Cell Disease and Trait among the Affected In a Tertiary Care Hospital in South Gujarat
Authors: Nagar Shashwat S , Patel Hirenkumar  B 
Published: May 2020

Introduction: Sickle cell disorder is an autosomal recessive condition, in which inheritance of an affected gene from both parents results in a disorder. SCD is more prevalent among the socio- economically disadvantaged and medically underserved communities mainly in Tapi District of Gujarat.
Objectives: 1.To study Awareness Regarding Sickle Cell Disease or Trait among the affected 2.To find out the association between the awareness level and the socio-demographic profile of the subjects.
Methodology: Descriptive Cross-sectional study was carried out in Janak Smarak hospital in Vyara Town, Tapi District, for a period of one year and minimum of 75 persons with SCD and 150 persons with SCT were taken for the study.
Results: The overall Knowledge regarding disease was averaging only at 15 %. The categorization of subject having “Good” or “Not so good” among the subject were predominantly poor with a majority of them showing Not so Good condition (84%) whereas only 16% showed good Knowledge.
Conclusion: The overall Knowledge regarding disease was averaging only at 15 % which showed that the awareness seems to be grossly deficit even among the affected. It hence shows that the counseling of the disease among the affected was not adequate. So Counselling & IEC can play a very important role to eliminate the disease from the community.
Docência Nômade – narrativas e deslocamentos na formação de professores em Artes Visuais
Authors: Nunes Aline 
Published: May 2020

A escrita propõe-se a pensar sobre a potência e as implicações de uma docência nômade frente aos processos formativos contemporâneos em Artes Visuais. Problematiza-se a ideia de docência nômade na qual, por meio da abordagem metodológica da Investigação Narrativa, são lançadas possibilidades de diálogo e experimentação em diferentes disciplinas ministradas em um curso de Licenciatura em Artes Visuais. Neste recorte a docência em artes visuais é tomada enquanto territorialidade, produzida e experienciada a partir dos agenciamentos entre os referenciais dos estudantes e aqueles lançados pela docente, ao longo de um semestre letivo.
First Michigan Record and Second Report of a Big-Headed Fly (Diptera: Pipunculidae) Parasitic upon Crane Flies (Diptera: Tipulidae)
Authors: TABER STEPHEN W. , STINE SARAH A. , KELLER OLIVER 
Published: May 2020

ABSTRACT
A recently discovered parasite of crane flies is reported for the first time from Michigan. The single previous report of such a natural enemy was the original discovery in Pennsylvania as published in 2007. A larva of a big-headed fly of the genus Nephrocerus Zetterstedt exited the abdomen of an adult female Tipula tephrocephala Loew that was caught while in flight. The host species and the state are new records for this parasitoid genus.
The Tortuous History of the Mutual-Mistake Defense in Michigan Contract Law
Authors: STOCKMEYER NORMAN OTTO 
Published: May 2020

ABSTRACT
Imagine a world where courts stopped enforcing contracts. There would be a complete breakdown in commerce. Yet courts do not enforce all contracts. Contracts that are the product of fraud or duress, for example, are voidable. The law must strike a balance between protecting legitimate expectations and policing against contract wrongdoing.
What if a contract is the product of a mistake? No one was at fault, yet the contract is not what the parties supposed. Should a court enforce it? Sherwood v. Walker (1887) is a landmark case in which the Michigan Supreme Court established the defense of mutual mistake, refusing to enforce a contract that was the product of the parties' erroneous assumption.
Sherwood v Walker is still taught in law schools today, and has been cited as authority by courts across the country. But since it was decided, Michigan's high court has twice repudiated the case, only to later embrace it again. This paper explores the convoluted history of the defense of mutual mistake in Michigan contract law.
What Happens to Plant Cover and Species Diversity When an Extensive Green Roof System Is Tilted? A Case Study on Green Roof Design, Old Mission Peninsula, Michigan
Authors: JONES ERIK , MILLER THERESA , MONSMA JEREMY , PUSZYKOWSKI JILLIAN , WESTPHAL JOANNE 
Published: May 2020

ABSTRACT
This paper describes plant species composition and coverage changes that occurred on an extensive (shallow) green roof system exposed to direct solar exposure and steep roof conditions over time. The green roof system, installed in August, 2005, involved a pre-seeded, manufactured mat product that initially was vegetated with twelve plant species. During the interim between installation and data collection for this paper, no maintenance, fertilizer, or irrigation was applied, despite the fact that observable differences in plant coverage were noted. In April, 2009, undergraduate student researchers revisited the green roof system and examined the green roof for species composition and absolute plant cover. These data were compared to a control area where solar incidence and slope were comparable to the conditions found on a flat roof system. This paper reports on the findings of this study, and offers insight to the types of modifications in extensive green roof technology that may be necessary if extensive green roof application is to be useful for steep roof conditions in cold climate environments.
Selected Topics on Socio-technical Perspective in Information Systems: Editorial Introduction to Issue 22 of CSIMQ
Authors: Bednar Peter , Nolte Alexander 
Published: May 2020

This thematic issue of the Complex Systems Informatics and Modeling Quarterly (CSIMQ) journal is dedicated to fostering a socio-technical perspective in the Information Systems (IS) field. The contemporary perspective has developed a lot over the years and the socio-technical agenda continues to be relevant. The issue contains a selection of extended papers presented at STPIS’19 – 5th International Workshop on Socio-Technical Perspective in IS Development held on June 10, 2019 in Stockholm, Sweden in conjunction with the 27th European Conference on Information Systems (ECIS). The workshop featured presentations of 13 papers and 3 posters and was attended by more than 30 participants from 8 different countries (Sweden, Norway, Finland, UK, Germany, Italy, Switzerland, and the US). Four of the presented papers were extended for publication in this special issue. The articles presented in this thematic issue contain at least 30% new material compared to the papers initially submitted for the workshop. The last included article was submitted as a regular contribution to the CSIMQ journal and was selected to be included into this thematic issue because of its close connection to the topic of socio-technical systems.
Spatial structure of boreal woodland caribou populations in northwest Canada
Authors: Wilson Steve , Sutherland Glenn , Larter Nicholas , Kelly Allicia , McLaren Ashley , Hodson James , Hegel Troy , Steenweg Robin , Hervieux Dave , Nudds Tom 
Published: May 2020

Local population units (LPUs) were delineated in Canada’s recovery strategy for threatened boreal woodland caribou (Rangifer tarandus caribou). Population viability analyses central to contemporary integrated risk assessments of LPUs implicitly assume geographic closure. Several LPUs in northwest Canada, however, were in part delineated by geopolitical boundaries and/or included large areas in the absence of evidence of more finely resolved population spatial structure. We pooled >1.2 million locations from >1200 GPS or VHF-collared caribou from northeast British Columbia, northwest Alberta and southwestern Northwest Territories. Bayesian cluster analysis generated 10 alternative candidate LPUs based on a spatial cluster graph of the extent of pairwise co-occurrence of collared caribou. Up to four groups may be artifacts in as yet under-sampled areas. Four were mapped LPUs that were conserved (Prophet, Parker, Chinchaga and Red Earth). One small group between Parker and Snake-Sahtaneh known locally as the “Fort Nelson core,” and outside any mapped LPU, was also conserved. Finally, one large group, at >136000 km2, spanned all three jurisdictions and subsumed all of six delineated LPUs (Maxhamish, Snake-Sahtaneh, Calendar, Bistcho, Yates, Caribou Mountains) and part of southern Northwest Territories. These results suggest less geographic closure of LPUs than those currently delineated, but further analyses will be required to better reconcile various sources of knowledge about local population structure in this region.
Identification of key miRNAs in the progression of hepatocellular carcinoma using an integrated bioinformatics approach
Authors: Zheng Qi , Wei Xiaoyong , Rao Jun , Zhou Cuncai 
Published: May 2020

Backgroud
It has been shown that aberrant expression of microRNAs (miRNAs) and transcriptional factors (TFs) is tightly associated with the development of HCC. Therefore, in order to further understand the pathogenesis of HCC, it is necessary to systematically study the relationship between the expression of miRNAs, TF and genes. In this study, we aim to identify the potential transcriptomic markers of HCC through analyzing common microarray datasets, and further establish the differential co-expression network of miRNAs–TF–mRNA to screen for key miRNAs as candidate diagnostic markers for HCC.

Method
We first downloaded the mRNA and miRNA expression profiles of liver cancer from the GEO database. After pretreatment, we used a linear model to screen for differentially expressed genes (DEGs) and miRNAs. Further, we used weighed gene co-expression network analysis (WGCNA) to construct the differential gene co-expression network for these DEGs. Next, we identified mRNA modules significantly related to tumorigenesis in this network, and evaluated the relationship between mRNAs and TFs by TFBtools. Finally, the key miRNA was screened out in the mRNA–TF–miRNA ternary network constructed based on the target TF of differentially expressed miRNAs, and was further verified with external data set.

Results
A total of 465 DEGs and 215 differentially expressed miRNAs were identified through differential genes expression analysis, and WGCNA was used to establish a co-expression network of DEGs. One module that closely related to tumorigenesis was obtained, including 33 genes. Next, a ternary network was constructed by selecting 256 pairs of mRNA–TF pairs and 100 pairs of miRNA–TF pairs. Network mining revealed that there were significant interactions between 18 mRNAs and 25 miRNAs. Finally, we used another independent data set to verify that miRNA hsa-mir-106b and hsa-mir-195 are good classifiers of HCC and might play key roles in the progression of HCC.

Conclusion
Our data indicated that two miRNAs—hsa-mir-106b and hsa-mir-195—are identified as good classifiers of HCC.
Yield, Quality and Economics of Various Rice Varieties of Telangana as Affected by Saline Irrigation Water under Different Agronomic Management Options
Authors: Prashanthi Botha , Suresh K. , Ramulu V. , Sridevi S. 
Published: May 2020

Aim: To evaluate the impact of saline irrigation water on yield, quality and economics of various rice varieties under different agronomic management options.
Study Design: The experiment was laid out in strip-plot design with three replications.
Place and Duration of Study: At College Farm, College of Agriculture, Rajendranagar, Hyderabad, during kharif, 2018.
Methodology: After the preliminary layout, local variety of dhaincha was broadcasted in the experimental site with seed rate of 40 kg ha-1 and incorporated during initiation of flowering in the respective treatment plots. Farm Yard Manure (FYM) (10 t ha-1) was applied and thoroughly mixed with the soil. Four rice varieties RNR-15048, KNM-118, JGL11118 and CSR-36 were were choosen because of its popularity in Telangana and raised well in advance and transplanted in respective treatments.
Results: The highest grain and straw yield was recorded by CSR 36 followed by (fb) RNR 15048 in combination with GM (In situ green manuring), Among the varieties, the highest amylose content was registered by JGL 11118 (24.16%) followed by RNR 15048 (21.9%). The highest L/B ratio was recorded by RNR 15048 (3.33) which was significantly higher than CSR 36 (3.20) and JGL 11118 (3.13). The highest head rice recovery was observed in CSR 36 which was on par with RNR 15048. In situ green manuring in RNR 15048 variety of Telangana received higher income. Under control treatment only the recommended dose of fertilizers (120:60:40 kg ha-1) was applied.
Conclusion: GM should therefore be done under saline water irrigation in registering superior yield, quality and economics in RNR 15048 in the district of Telangana.
Dosimetric impact of tracheostomy devices in head and neck cancer patients
Authors: Lee Justin , Ramadan Sherif , Kim Anthony , Alayed Yasir , Ravi Ananth 
Published: May 2020

AbstractIntroductionThe tracheostomy site and adjacent skin is at risk for recurrence in head/neck squamous cell cancer patients. The tracheostomy tube is an in situ device located directly over the tracheostomy site and may have clinical implications on the radiation dose delivered to the peristomal region. This study aimed to investigate this effect by comparing the prescribed treatment planning dose with the actual dose in vivo to the peristomal clinical target region. A retrospective, dosimetric study was performed with approval of the institutional research ethics board.MethodsFifteen patients who had received high‐dose radiotherapy to the tracheostomy region with in vivo dose measurements were included. The radiation dose at the skin surface underneath the tracheostomy device was measured using an optically stimulated luminescent dosimeter (OSLD) and was compared with the prescribed dose from the radiation planning system. The effect of the tracheostomy flange and/or soft tissue equivalent bolus on the peristomal dose was calculated.Results and discussionPatients with tracheostomy equipment in situ were found to have a 3.7% difference between their prescribed and actual dose. With a tissue equivalent bolus there was a 2.0% difference between predicted and actual. The mean prescribed single fraction dose (mean = 191.8 cGy, SD = 40.18) and OSLD measured dose (mean = 194.02 cGy, SD = 44.3) were found to have no significant difference. However, with the flange excluded from the planning simulation (density = air) target skin dose deviated from predicted by an average of 55.3% (range = 12.4–72.9, SD = 22.5) and volume coverage was not achieved.ConclusionIn summary, the tracheostomy flange acts like bolus with a twofold increase in the skin surface dose. Changes in the peristomal apparatus from simulation to treatment needs to be considered to ensure that the simulated dose and coverage is achieved.