bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors predicting 10-year seizure freedom after temporal lobe resection
Authors: Schmitt Friedhelm C. , Meencke H.‑Joachim 
Published: January 2020

Abstract
Background
Resective surgery is an established and evidence-based treatment approach in pharmacoresistant temporal lobe epilepsy (TLE). Extra-long-term follow-up data are important to allow for good patient counseling. So far, only few trials provide prospective or retrospective data exceeding 5 years.

Objective
This study aimed to present data of continuous seizure outcome over an extended time period, with a particular focus on patients who remained seizure free for 10 years.

Methods
We analyzed seizure outcome after epilepsy surgery for TLE in 46 consecutive patients, who were seen on an annual basis for 10 years in a single center (Epilepsy Center Berlin Brandenburg). Factors for remaining seizure free for 10 years were determined by univariate analysis.

Results
The class I outcome changed each year by 74–78%. Of the patients, 63% remained continuously in Engel class I (48% Engel Class IA for 10 years) for 10 years. Six patients were never seizure free (12.5%). After 10 years, 35% of the patients were cured (i.e., seizure-free without medication). A higher number of antiepileptic drugs and seizures before surgery as well as the indication for invasive presurgical monitoring were associated with “unsuccessful surgery.”

Conclusion
With almost half of the patients completely seizure free and more than a third “cured,” epilepsy surgery remains the mainstay of therapy for TLE patients. Analysis in larger cohorts with extra-long-term follow-up is needed to assess good prognostic factors and other postsurgical outcome issues such as neuropsychological, psychiatric, and psychosocial outcomes.
Genome-wide association analysis of stripe rust resistance loci in wheat accessions from southwestern China
Authors: Cheng Bin , Gao Xu , Cao Ning , Ding Yanqing , Gao Yu , Chen Tianqing , Xin Zhihai , Zhang Liyi 
Published: January 2020

AbstractWheat stripe rust can cause considerable yield losses, and genetic resistance is the most effective approach for controlling the disease. To identify the genomic regions responsible for Puccinia striiformis f. sp. tritici (Pst) resistance in a set of winter wheat strains mainly from southwestern China, and to identify DNA markers in these regions, we carried out a genome-wide association study (GWAS) of 120 China winter wheat accessions using single nucleotide polymorphism (SNP) markers from 90K wheat SNP arrays. In total, 16 SNP loci were significantly associated with wheat stripe rust in field and greenhouse trials. Of these, three distinctive SNPs on chromosomes 1B, 4A, and 6A were identified at a site in Mianyang in 2014, where the most prevalent wheat stripe rust races since 2009 have been V26 (G22-9, G22-14). This suggests that the three SNP loci were linked to the new quantitative trait loci (QTL)/genes resistant to the V26 races. Germplasm with immunity to Pst is a good source of stripe rust resistance for breeding, and after further validation, SNPs closely linked to resistance QTLs/genes could be converted into user-friendly markers and facilitate marker-assisted selection to improve wheat stripe rust resistance.
Comparative study of dust acoustic solitons in two-temperature ion homogeneous and inhomogeneous plasmas
Authors: Srivastava Rashmi , Malik Hitendra K. , Singh Devi 
Published: January 2020

AbstractThe dust acoustic solitary waves are theoretically investigated in dusty plasmas for different cases of with and without density gradients. These low-frequency solitary waves are studied using appropriate Korteweg–de Vries equations obtained using relevant stretched coordinates. The soliton solutions in homogeneous plasma, weakly inhomogeneous plasma and strongly inhomogeneous plasma, are thoroughly investigated for studying the effect of different parameters like dust charge and density of all the plasma species on the soliton profiles. The combination of the dust charge with its number density changes the dynamics of the solitons and that is further affected by the number density of the hot ion with respect to the cold ions.
Emotion Recognition from Multimodal Physiological Signals for Emotion Aware Healthcare Systems
Authors: Ayata Değer , Yaslan Yusuf , Kamasak Mustafa E. 
Published: January 2020

Abstract
Purpose
The purpose of this paper is to propose a novel emotion recognition algorithm from multimodal physiological signals for emotion aware healthcare systems. In this work, physiological signals are collected from a respiratory belt (RB), photoplethysmography (PPG), and fingertip temperature (FTT) sensors. These signals are used as their collection becomes easy with the advance in ergonomic wearable technologies.

Methods
Arousal and valence levels are recognized from the fused physiological signals using the relationship between physiological signals and emotions. This recognition is performed using various machine learning methods such as random forest, support vector machine and logistic regression. The performance of these methods is studied.

Results
Using decision level fusion, the accuracy improved from 69.86 to 73.08% for arousal, and from 69.53 to 72.18% for valence. Results indicate that using multiple sources of physiological signals and their fusion increases the accuracy rate of emotion recognition.

Conclusion
This study demonstrated a framework for emotion recognition using multimodal physiological signals from respiratory belt, photo plethysmography and fingertip temperature. It is shown that decision level fusion from multiple classifiers (one per signal source) improved the accuracy rate of emotion recognition both for arousal and valence dimensions.
In-Fiber Structured Particles and Filament Arrays from the Perspective of Fluid Instabilities
Authors: Xu Bingrui , Ma Shuqi , Xiang Yuanzhuo , Zhang Jing , Zhu Meifang , Wei Lei , Tao Guangming , Deng Daosheng 
Published: January 2020

AbstractIn-fiber structured particles and filament array have been recently emerging, providing unique advantages of feasible fabrication, diverse structures and sophisticated functionalities. This review will focus on the progress of this topic mainly from the perspective of fluid instabilities. By suppressing the capillary instability, the uniform layered structures down to nanometers are attained with the suitable materials selection. On the other hand, by utilizing capillary instability via post-drawing thermal treatment, the unprecedent structured particles can be designed with multimaterials for multifunctional fiber devices. Moreover, an interesting filamentation instability of a stretching viscous sheet has been identified during thermal drawing, resulting in an array of filaments. This review may inspire more future work to produce versatile devices for fiber electronics, either at a single fiber level or in large-scale fabrics and textiles, simply by manipulating and controlling fluid instabilities.
Perception of Labial Size and Objective Measurements-Is There a Correlation? A Cross-Sectional Study in a Cohort Not Seeking Labiaplasty
Authors: Widschwendter Andreas , Riedl David , Freidhager Katharina , Abdel Azim Samira , Jerabek-Klestil Susanne , D'Costa Elisabeth , Fessler Siegfried , Ciresa-König Alexandra , Marth Christian , Böttcher Bettina 
Published: January 2020

Abstract

Introduction
Poor genital self-image is a common phenomenon leading to an increasing interest in female genital surgery over the last years.

Aim
The aim was to correlate objective measurements of the labia minora with the individual subjective perception of the labial size.

Methods
In a cross-sectional study with 200 premenopausal women (median age 33.5 years) presenting for gynecological issues other than vulvar diseases, labial width and length were measured, and psychological and physical complaints were assessed. Multivariable logistic regression analyses were performed to identify factors that influenced self-reported complaints and subjective perception of labia size.

Main Outcome Measure
The main outcome measure was labial appearance (width and length in mm, color), subjective perception of the labial size, and complaints.

Results
The median width of the labia minora was 19.0 mm (interquartile range = 12.6–27.5), and the median length was 35.5 mm (interquartile range = 27.8–48.9). The objective size of the labia was significantly associated with womens' subjective perception of the labial size, but not with self-reported complaints. Nearly one-third of the women (n = 53, 27%) reported complaints of their labia minora which were mainly physical (n = 41, 77%) or a combination of physical and psychological problems (n = 9, 17%), while only a small group reported experiencing only psychological complaints (n = 3, 6%). Predictors of complaints were previous cosmetic surgery and the subjective perception of the labia size. The latter was significantly associated with discomfort during intercourse and when visiting a sauna and by labia minora that protruded over the labia majora.

Clinical Implications
Cutoff values to define labial hypertrophy and to justify labial reduction surgery should be avoided.

Strength & Limitations
This is a large sample of labial measurements in women not seeking labiaplasty. Standardized and validated questions regarding quality of life, sexuality, and body image could have provided more insight into psychological aspects.

Conclusion
These data demonstrate the variability of labial anatomy and its perception.
Moment-to-moment dynamics between auditory verbal hallucinations and negative affect and the role of beliefs about voices
Authors: So Suzanne Ho-wai , Chung Lawrence Kin-hei , Tse Chun-Yu , Chan Sandra Sau-man , Chong George Heung-chuen , Hung Karen Shee-yueng , Sommer Iris E. C. 
Published: January 2020

AbstractBackgroundNegative affect (NA) has been suggested to be both an antecedent and a consequence of auditory verbal hallucinations (AVH). Furthermore, negative appraisals of voices have been theorized to contribute to the maintenance of AVH. Using the experience sampling method (ESM), this study examined the bi-directional relationship between NA and AVH, and the moderating effect of negative beliefs about voices.MethodsForty-seven patients diagnosed with schizophrenia spectrum disorders with frequent AVH completed a clinical interview, followed by ESM for 10 times a day over 6 days on an electronic device. Time-lagged analyses were conducted using multilevel regression modeling. Beliefs about voices were assessed at baseline.ResultsA total of 1654 data points were obtained. NA predicted an increase in AVH in the subsequent moment, and AVH predicted an increase in NA in the subsequent moment. Baseline beliefs about voices as malevolent and omnipotent significantly strengthened the association between NA and AVH within the same moment. In addition, the belief of omnipotence was associated with more hallucinatory experiences in the moment following NA. However, beliefs about voices were not associated directly with momentary levels of NA or AVH.ConclusionsExperiences of NA and AVH drove each other, forming a feedback loop that maintained the voices. The associations between NA and AVH, either within the same moment or across moments, were exacerbated by negative beliefs about voices. Our results suggest that affect-improving interventions may stop the feedback loop and reduce AVH frequency.
Abnormal reward valuation and event-related connectivity in unmedicated major depressive disorder
Authors: Rupprechter S. , Stankevicius A. , Huys Q. J. M. , Series P. , Steele J. D. 
Published: January 2020

AbstractBackgroundExperience of emotion is closely linked to valuation. Mood can be viewed as a bias to experience positive or negative emotions and abnormally biased subjective reward valuation and cognitions are core characteristics of major depression.MethodsThirty-four unmedicated subjects with major depressive disorder and controls estimated the probability that fractal stimuli were associated with reward, based on passive observations, so they could subsequently choose the higher of either their estimated fractal value or an explicitly presented reward probability. Using model-based functional magnetic resonance imaging, we estimated each subject's internal value estimation, with psychophysiological interaction analysis used to examine event-related connectivity, testing hypotheses of abnormal reward valuation and cingulate connectivity in depression.ResultsReward value encoding in the hippocampus and rostral anterior cingulate was abnormal in depression. In addition, abnormal decision-making in depression was associated with increased anterior mid-cingulate activity and a signal in this region encoded the difference between the values of the two options. This localised decision-making and its impairment to the anterior mid-cingulate cortex (aMCC) consistent with theories of cognitive control. Notably, subjects with depression had significantly decreased event-related connectivity between the aMCC and rostral cingulate regions during decision-making, implying impaired communication between the neural substrates of expected value estimation and decision-making in depression.ConclusionsOur findings support the theory that abnormal neural reward valuation plays a central role in major depressive disorder (MDD). To the extent that emotion reflects valuation, abnormal valuation could explain abnormal emotional experience in MDD, reflect a core pathophysiological process and be a target of treatment.
Joseph Johnson's Lost Gamuts: Native Hymnody, Materials of Exchange, and the Colonialist Archive
Authors: GOODMAN GLENDA 
Published: January 2020

AbstractIn the winter of 1772–1773, Joseph Johnson (Mohegan/Brothertown) copied musical notation into eight books for Christian Native Americans in Farmington, Connecticut, a town established by English settler colonists on the land known as Tunxis Sepus. Johnson did so because, as he wrote in his diary, “The indians are all desireous of haveing Gamuts.” Johnson's “gamuts” have not survived, but their erstwhile existence reveals hymnody's important role within the Native community in Farmington as well as cross-culturally with the English settler colonists. In order to reconstruct the missing music books and assess their sociocultural significance, this article proposes a surrogate bibliography, gathering a constellation of sources among which Johnson's books would have circulated and gained meaning for Native American Christians and English colonists (including other printed and manuscript music, wampum, and legal documents pertaining to land transfer). By bringing together this multi-modal network of materials, this essay seeks to redress the material and epistemological effects of a colonialist archive. On one level, this is a case study that focuses on a short period of time in order to document the impact on sacred music of conversion, literacy, shifting intercultural relations, and a drive to preserve sovereignty. On another, this article presents a methodological intervention for dealing with lost materials and colonialist archives without recourse to discourses of recovery or discovery, the latter of which is considered through the framework of what I term “archival orientalism.”
Teratogenic effects ofBocconia frutescensL.
Authors: Lunagómez L. S. , Santiago-Roque I. , Gheno-Heredia Y. A. , Corona-Morales A. A. , Bolado-García V. E. 
Published: January 2020

AbstractIt is estimated that 80% of the world population trusts traditional medicine. A large number of Americans use infusions ofBocconia frutescensL. leaves to treat cough and gastrointestinal disorders. However, phytochemical studies reveal that this plant contains alkaloids and other potentially harmful substances. This study aimed to evaluate the teratogenic effects ofB. frutescensL. in an experimental model. Pregnant Wistar rats were administered lyophilizedB. frutescensL. extract at 300 mg/kg/day or vehicle by orogastric route during the organogenesis period (gestation days 7–13), and external and internal congenital malformations were analyzed on the progeny on gestational day 20.Bocconia frutescensL. produced a significant increase in the number of different malformations, relative to the control group. We conclude that the consumption ofB. frutescensL. during pregnancy at a dose equivalent to that consumed by humans increases the risk of teratogenic effects.
Commensal Hafnia alvei strain reduces food intake and fat mass in obese mice—a new potential probiotic for appetite and body weight management
Authors: Legrand Romain , Lucas Nicolas , Dominique Manon , Azhar Saida , Deroissart Camille , Le Solliec Marie-Anne , Rondeaux Julie , Nobis Séverine , Guérin Charlène , Léon Fatima , do Rego Jean-Claude , Pons Nicolas , Le Chatelier Emmanuelle , Ehrlich S. Dusko , Lambert Gregory , Déchelotte Pierre , Fetissov Sergueï O. 
Published: January 2020

Abstract
Background/objectives
Based on the recent identification of E.coli heat shock protein ClpB as a mimetic of the anorexigenic α-melanocyte stimulating hormone (α-MSH), the objective of this study was to preclinically validate Hafnia alvei, a ClpB-producing commensal bacterium as a potential probiotic for appetite and body weight management in overweight and obesity.

Methods
The involvement of enterobacterial ClpB in the putative anti-obesity effects was studied using ClpB-deficient E.coli. A food-grade H. alvei HA4597 strain synthetizing the ClpB protein with an α-MSH-like motif was selected as a candidate probiotic to be tested in ob/ob and high-fat diet (HFD)-fed obese and overweight mice. The relevance of the enterobacterial ClpB gene to human obesity was studied by in silico analysis of fecal metagenomes of 569 healthy individuals from the “MetaHIT” database.

Results
Chronic per os administration of native but not ClpB-deficient E.coli strain reduced body weight gain (p < 0.05) and daily meal frequency (p < 0.001) in ob/ob mice. Oral gavage of H.alvei for 18 and 46 days in ob/ob and HFD-fed obese mice, respectively, was well tolerated, reduced body weight gain and fat mass in both obesity models (p < 0.05) and decreased food intake in hyperphagic ob/ob mice (p < 0.001). Elevated fat tissue levels of phosphorylated hormone-sensitive lipase were detected in H.alvei -treated ob/ob mice (p < 0.01). Enterobacterial ClpB gene richness was lower in obese vs. non-obese humans (p < 0.0001) and correlated negatively with BMI in genera of Enterobacter, Klebsiella and Hafnia.

Conclusions
H.alvei HA4597 strain reduces food intake, body weight and fat mass gain in hyperphagic and obese mice. These data combined with low enterobacterial ClpB gene abundance in the microbiota of obese humans provide the rationale for using H.alvei as a probiotic for appetite and body weight management in overweight and obesity.
Neonatal abstinence syndrome management in California birth hospitals: results of a statewide survey
Authors: Clemans-Cope Lisa , Holla Nikhil , Lee Henry C. , Cong Allison Shufei , Castro Robert , Chyi Lisa , Huang Angela , Taylor Kimá Joy , Kenney Genevieve M. 
Published: January 2020

Abstract
Objective
Assess management of neonatal abstinence syndrome (NAS) in California hospitals to identify potential opportunities to expand the use of best practices.

Study design
We fielded an internet-based survey of 37 questions to medical directors or nurse managers at 145 birth hospitals in California.

Results
Seventy-five participants (52%) responded. Most respondents reported having at least one written protocol for managing NAS, but gaps included protocols for pharmacologic management. Newer tools for assessing NAS severity were not commonly used. About half reported usually or always using nonpharmacologic strategies; there is scope for increasing breastfeeding when recommended, skin-to-skin care, and rooming-in.

Conclusions
We found systematic gaps in care for infants with NAS in a sample of California birth hospitals, as well as opportunities to spread best practices. Adoption of new approaches will vary across hospitals. A concerted statewide effort to facilitate such implementation has strong potential to increase access to evidence-based treatment for infants and mothers.
Microstructural constraints on magmatic mushes under Kīlauea Volcano, Hawaiʻi
Authors: Wieser Penny E. , Edmonds Marie , Maclennan John , Wheeler John 
Published: January 2020

AbstractDistorted olivines of enigmatic origin are ubiquitous in erupted products from a wide range of volcanic systems (e.g., Hawaiʻi, Iceland, Andes). Investigation of these features at Kīlauea Volcano, Hawaiʻi, using an integrative crystallographic and chemical approach places quantitative constraints on mush pile thicknesses. Electron backscatter diffraction (EBSD) reveals that the microstructural features of distorted olivines, whose chemical composition is distinct from undistorted olivines, are remarkably similar to olivines within deformed mantle peridotites, but inconsistent with an origin from dendritic growth. This, alongside the spatial distribution of distorted grains and the absence of adcumulate textures, suggests that olivines were deformed within melt-rich mush piles accumulating within the summit reservoir. Quantitative analysis of subgrain geometry reveals that olivines experienced differential stresses of ∼3–12 MPa, consistent with their storage in mush piles with thicknesses of a few hundred metres. Overall, our microstructural analysis of erupted crystals provides novel insights into mush-rich magmatic systems.
TGF-β induces ST2 and programs ILC2 development
Authors: Wang Li , Tang Jun , Yang Xia , Zanvit Peter , Cui Kairong , Ku Wai Lim , Jin Wenwen , Zhang Dunfang , Goldberg Nathan , Cain Alexander , Ni Bing , Zhao Keji , Wu Yuzhang , Chen WanJun 
Published: January 2020

AbstractThe molecular pathways underlying the development of innate lymphoid cells (ILCs) are mostly unknown. Here we show that TGF-β signaling programs the development of ILC2s from their progenitors. Specifically, the deficiency of TGF-β receptor II in bone marrow progenitors results in inefficient development of ILC2s, but not ILC1s or ILC3s. Mechanistically, TGF-β signaling is required for the generation and maintenance of ILC2 progenitors (ILC2p). In addition, TGF-β upregulates the expression of the IL-33 receptor gene Il1rl1 (encoding IL-1 receptor-like 1, also known as ST2) in ILC2p and common helper-like innate lymphoid progenitors (CHILP), at least partially through the MEK-dependent pathway. These findings identify a function of TGF-β in the development of ILC2s from their progenitors.