bluuebunny/crossref_metadata_2025_split huggingface dataset:
DeConFuse: a deep convolutional transform-based unsupervised fusion framework
Authors: Gupta Pooja , Maggu Jyoti , Majumdar Angshul , Chouzenoux Emilie , Chierchia Giovanni 
Published: May 2020

AbstractThis work proposes an unsupervised fusion framework based on deep convolutional transform learning. The great learning ability of convolutional filters for data analysis is well acknowledged. The success of convolutive features owes to the convolutional neural network (CNN). However, CNN cannot perform learning tasks in an unsupervised fashion. In a recent work, we show that such shortcoming can be addressed by adopting a convolutional transform learning (CTL) approach, where convolutional filters are learnt in an unsupervised fashion. The present paper aims at (i) proposing a deep version of CTL, (ii) proposing an unsupervised fusion formulation taking advantage of the proposed deep CTL representation, and (iii) developing a mathematically sounded optimization strategy for performing the learning task. We apply the proposed technique, named DeConFuse, on the problem of stock forecasting and trading. A comparison with state-of-the-art methods (based on CNN and long short-term memory network) shows the superiority of our method for performing a reliable feature extraction.
Exploring prevention and mitigation strategies to reduce the health impacts of occupational exposure to wildfires for wildland firefighters and related personnel: protocol of a scoping study
Authors: Koopmans Erica , Fyfe Trina , Eadie Mike , Pelletier Chelsea A. 
Published: May 2020

AbstractBackgroundWith an increase in wildfire activity across the globe and growing numbers of personnel involved each year, it is necessary to explore the health impacts of occupational exposure to wildfires and the practices and policies that can be implemented to mitigate these effects. The aim of this work is to (1) identify the impact occupational exposure to wildfires has on health outcomes including physical, mental, and social wellbeing; (2) examine the characteristics and effectiveness of mitigation strategies or policies to reduce negative health impacts as reported by current literature and reports; and (3) develop a program of research to address and understand the health impacts of occupational exposure to wildfires based on gaps in the literature and stakeholder priorities.MethodsThis scoping study will be conducted in two phases: (1) scoping literature review and (2) modified Delphi process. The literature review will follow a methodologically rigorous scoping review approach that includes (a) identifying the research question (and protocol development), (b) identifying literature (an iterative process), (c) selecting relevant studies, (d) extracting data into tables, and (e) synthesizing, summarizing, and reporting results. Alongside this, a modified Delphi process will be conducted to define priorities for wildland fire occupational health research. A partnership with the British Columbia (BC) Wildfire Service will enable exploring the appropriateness of identified mitigation strategies and health risks for the BC context.DiscussionThis two-phase approach will provide an in-depth review of the literature of the health impacts of occupational exposure to wildfires and identify mitigation strategies or policies implemented to protect workers and reduce negative health impacts. It is anticipated that these findings may provide recommendations for “quick wins” or initial action that can be implemented within the BC context to reduce negative health outcomes, and inform gaps in context-specific research that needs to be addressed through a strategic, collaborative research program over the next 5 years.Systematic review registrationOpen Science Frameworkosf.io/ugz4
The arbitrary-order fractional hyperbolic nonlinear scalar conservation law
Authors: Shirkhorshidi S. M. Reza , Rostamy D. , Othman W. A. M. , Awang M. A. Omar 
Published: May 2020

AbstractIn this paper, we use a new powerful technique of arbitrary-order fractional (AOF) characteristic method (CM) to solve the AOF hyperbolic nonlinear scalar conservation law (HNSCL) of time and space. We present the existence and uniqueness of this class of equations in time and one-dimensional space of fractional arbitrary order. We extend Jumarie’s modification of Riemann–Liouville and Caputo’s definition of the fractional arbitrary order to introduce some formulae (Appl. Math. Lett. 22:378–385, 2009; Appl. Math. Lett. 18:739–748, 2005). Then, we use these formulae to prove the main theorem. In the application section, we use the analytical technique that is presented in the theorem to solve examples that are given.
Quadratic covariations for the solution to a stochastic heat equation with space-time white noise
Authors: Sun Xichao , Yan Litan , Yu Xianye 
Published: May 2020

AbstractLet $u(t,x)$u(t,x) be the solution to a stochastic heat equation $$ \frac{\partial }{\partial t}u=\frac{1}{2} \frac{\partial ^{2}}{\partial x^{2}}u+ \frac{\partial ^{2}}{\partial t\,\partial x}X(t,x),\quad t\geq 0, x\in { \mathbb{R}} $$∂∂tu=12∂2∂x2u+∂2∂t∂xX(t,x),t≥0,x∈R with initial condition $u(0,x)\equiv 0$u(0,x)≡0, where Ẋ is a space-time white noise. This paper is an attempt to study stochastic analysis questions of the solution $u(t,x)$u(t,x). In fact, it is well known that the solution is a Gaussian process such that the process $t\mapsto u(t,x)$t↦u(t,x) is a bi-fractional Brownian motion with Hurst indices $H=K=\frac{1}{2}$H=K=12 for every real number x. However, the many properties of the process $x\mapsto u(\cdot ,x)$x↦u(⋅,x) are unknown. In this paper we consider the generalized quadratic covariations of the two processes $x\mapsto u(\cdot ,x),t\mapsto u(t,\cdot )$x↦u(⋅,x),t↦u(t,⋅). We show that $x\mapsto u(\cdot ,x)$x↦u(⋅,x) admits a nontrivial finite quadratic variation and the forward integral of some adapted processes with respect to it coincides with “Itô’s integral”, but it is not a semimartingale. Moreover, some generalized Itô formulas and Bouleau–Yor identities are introduced.
Autumn migration direction of juvenile willow warblers (Phylloscopus t. trochilus and P. t. acredula) and their hybrids assessed by qPCR SNP genotyping
Authors: Zhao Tianhao , Ilieva Mihaela , Larson Keith , Lundberg Max , Neto Júlio M. , Sokolovskis Kristaps , Åkesson Susanne , Bensch Staffan 
Published: May 2020

Abstract
Backgrounds
Geographic regions, where two closely related taxa with different migration routes come into contact, are known as migratory divides. Hybrids originating from migratory divides are hypothesized to migrate intermediately relative to the parental populations. Few studies have tested this hypothesis in wild birds, and only in hybrids that have completed the migration back to the breeding grounds. Here, we make use of the well-established migration routes of willow warblers (Phylloscopus trochilus), for which the subspecies trochilus and acredula have migration-associated genetic markers on chromosomes 1 and 5. The genetic approach enabled us to analyze the geographic distribution of juveniles during their first autumn migration, predicting that hybrids should be more frequent in the central flyway over Italy than along the typical SW routes of trochilus and SE routes of acredula.

Methods
Blood and feather samples were collected from wintering birds in Africa (n = 69), and from juveniles during autumn migration in Portugal (n = 33), Italy (n = 38) and Bulgaria (n = 32). Genotyping was carried out by qPCR SNP assays, on one SNP each on chromosome 1 (SNP 65) and chromosome 5 (SNP 285). Both these SNPs have alternative alleles that are highly fixed (> 97%) in each of the subspecies.

Results
The observed combined genotypes of the two SNPs were associated with the known migration routes and wintering distributions of trochilus and acredula, respectively. We found hybrids (HH) among the juveniles in Italy (5/38) and in Portugal (2/33). The proportion of hybrids in Italy was significantly higher than expected from a background rate of hybrid genotypes (1.5%) in allopatric populations of the subspecies.

Conclusions
Our genetic approach to assign individuals to subspecies and hybrids allowed us to investigate migration direction in juvenile birds on their first migration, which should better reflect the innate migratory direction than studies restricted to successful migrants. The excess of hybrids in Italy, suggests that they employ an intermediate route relative to the parental populations. Our qPCR SNP genotyping method is efficient for processing large sample sizes, and will therefore be useful in migration research of species with known population genetic structure.
TRAF3 can interact with GMEB1 and modulate its anti-apoptotic function
Authors: Kotsaris George , Kerselidou Despoina , Koutsoubaris Dimitrios , Constantinou Elena , Malamas George , Garyfallos Dimitrios A. , Ηatzivassiliou Eudoxia G. 
Published: May 2020

Abstract
Background
Members of Tumor Necrosis Factor (TNF) Receptor-Associated Factors (TRAFs) family interact with the cytoplasmic tails of TNF receptor family members to mediate signal transduction processes. TRAF3 has a major immunomodulatory function and TRAF3 deficiency has been linked to malignancies, such as multiple myeloma and lymphoid defects. In order to characterize the molecular mechanisms of TRAF3 signaling, the yeast two-hybrid system was used to identify proteins that interact with TRAF3.

Results
The yeast two-hybrid screen of a human B cell cDNA library with TRAF3 as bait, identified Glucocorticoid Modulatory Element-Binding Protein 1 (GMEB1) as a TRAF3-interacting protein. Previous studies indicated that GMEB1 functions as a potent inhibitor of caspase activation and apoptosis. The interaction of TRAF3 and GMEB1 proteins was confirmed in mammalian cells lines, using immunoprecipitation assays. The RING and TRAF-C domains of TRAF3 were not essential for this interaction. The overexpression of TRAF3 protein enhanced the anti-apoptotic function of GMEB1 in HeLa cells. On the other hand, downregulation of TRAF3 by RNA interference decreased significantly the ability of GMEB1 to inhibit apoptosis. In addition, LMP1(1–231), a truncated form of the EBV oncoprotein LMP1, that can interact and oligomerize with TRAF3, was also able to cooperate with GMEB1, in order to inhibit apoptosis.

Conclusions
Our protein-interaction experiments demonstrated that TRAF3 can interact with GMEB1, which is an inhibitor of apoptosis. In addition, cell viability assays showed that overexpression of TRAF3 enhanced the anti-apoptotic activity of GMEB1, supporting a regulatory role of TRAF3 in GMEB1-mediated inhibition of apoptosis. Better understanding of the molecular mechanism of TRAF3 function will improve diagnostics and targeted therapeutic approaches for TRAF3-associated disorders.
Malignant adenomyoepithelioma of the breast
Authors: Moro Kazuki , Sakata Eiko , Nakahara Asa , Hashidate Hideki , Gabriel Emmanuel , Makino Haruhiko 
Published: May 2020

Abstract
Background
Adenomyoepithelioma (AME) of the breast is a very rare tumor and is generally considered to be benign. However, some show malignant transformation, which results in local recurrences or distant metastases. The morphological features of AME that might predict malignant potential have not been elucidated. Moreover, there is also no established multidisciplinary treatment for malignant AME aside from complete excision at an early stage.

Case presentation
A 64-year-old female diagnosed with AME of the left breast underwent lumpectomy. The surgical margins were negative. Six months after the operation, however, malignant AME recurred locally in the left breast. MRI showed multiple masses, which invaded the skin. A left mastectomy with axillary lymph node dissection was performed. Additional areas of AME were found in about one third of the entire breast. Eight months after the mastectomy, lung metastases were detected. She underwent chemotherapy with fluorouracil, epirubicin, and cyclophosphamide (FEC) for 9 cycles with little response. Lung metastasectomy was performed. Nine months after lung metastasectomy, the metastases were widespread to the brain, heart, and kidney; she subsequently died 2 months later.

Conclusions
Malignant AME has various morphological features, and in this report, we characterize new findings from both imaging and pathology/autopsy. Malignant potency is related to the tumor size, tumor appearance, and mitoses, even if only a few. Given that ductal spread is one of the morphological features of malignant AME, it is of paramount importance to assess the surgical margins.
Analysis of corporate sustainability performance and corporate financial performance causal linkage in the Indian context
Authors: Jha Milind Kumar , Rangarajan K. 
Published: May 2020

AbstractThis paper aims to explore the relationship between corporate sustainability performance (CSP) and corporate firm performance (CFP) for a sample of the top 500 Indian firms covering the period from 2008 to 2018. CSP variables have been considered at both aggregate and disaggregate levels of environmental, social and governance performance. CFP has been evaluated in both accounting and market-based measures. Rigorous statistical methods have been used to evaluate the bidirectional causality and intensity of the CSP-CFP relationship using the Granger causality test and multiple regression for panel data. A sectoral level trend analysis is presented dividing the firms in various industries and classifying them in ESI vs non-ESI sectors. The findings indicate the absence of causality among CSP and CFP variables in either direction and suggest that the CSP-CFP linkage is mostly insignificant for Indian firms at the aggregate level. At an individual level, some negative association is found between CSP and CFP. This relationship has an adverse impact on CSP-CFP linkage in both cases, which means that Indian firms don’t get the financial performance benefits of investments done for sustainability. Our findings with mostly insignificant results for this relation also means that firms with higher or lower CSP on ESG dimensions will perform likewise in terms of CFP. The findings have practical implications for corporates, academicians, and policymakers alike given sustainability as a high focus area for all.
l-carnitine acts as a neuroprotecor against aspartame injury in Wistar albino rat
Authors: Hamza Reham Z. , Al-Eisa Rasha A. , El-Shenawy Nahla S. 
Published: May 2020

AbstractBackgroundl-carnitine(LC) plays an important role in the oxidative/antioxidative balance of different organs. The study has explored the effect of the daily administration of aspartame (ASP) at two different doses for 4 weeks induces oxidative stress, inflammation, and histopathology in the brain of rats. This study also focused on explaining whetherl-carnitine (LC) has potential ameliorative effects against pathophysiology induced by ASP in the brain. Adult male Wistar rats were split into six groups as follows: control animals were administered with vehicle, group of ASP at a low dose (ASP-LD) was given 75 mg/kg B.W., high dose of ASP (ASP-HD; 150 mg/kg), animals were treated with LC (10 mg/kg), ASP-LD + LC group and ASP-HD + LC treated rats.ResultsASP induced large increments in cytokines of interleukin-6, tumor necrosis factor-α, myeloperoxidase, xanthine oxidase, cyclooxygenase-2, and prostaglandin E2 in a dose-dependent response of the brain. Activities of superoxide dismutase/catalase, glutathione peroxidase, and acetylcholinesterase, besides levels of thiol, glutathione, a brain-derived neurotrophic factor, and neurotransmitters, were decreased in the brain tissue. The inauguration of brain injury by ASP administration was depended on the dose of treatment. Co-administration of LC with ASP significantly reversed and corrected all the abovementioned parameters.ConclusionThe data confirm that LC attenuated ASP neurotoxicity by suppressing the inflammation, oxidative stress and improving the neurotransmitters, antioxidants coupled with the histological and cellular structure.
Uneven solidarity: the school strikes for climate in global and intergenerational perspective
Authors: Walker Catherine 
Published: May 2020

Abstract
Background
The school strikes for climate (henceforth, the school strikes) initiated by Greta Thunberg have brought young people’s environmental concerns to the global stage. However, there is a danger of considering youth environmental concerns only through the actions of highly mobilised young people who are heavily concentrated in the urban Global North. This article revisits qualitative data collected before the school strikes to consider how 11–14-year-olds in India and England interpreted and responded to environmental hazards and degradation in their everyday lives, and connected their situated experiences to narratives of global environmental crisis. The young people occupied a range of socio-economic positions and were experiencing different degrees of vulnerability to environmental hazards.

Results
All of the research participants were concerned about the future of the planet and their immediate environments. However, for the most environmentally vulnerable participants, future- and globally-oriented environmental concerns were overpowered by more immediate concerns. Although the young people were engaged in responses to environmental concerns, they did not see themselves as acting alone but rather with others around them, often adults. Some young people expressed doubt about the extent to which they as generationally-positioned individuals could make a difference to the problems discussed. These findings in many ways anticipate the school strikes, wherein young people are taking action to call upon adults to respond to environmental problems that young people recognise are beyond their individual capacities to resolve.

Conclusion
The environmental activism of a significant minority of young people is to be applauded, however, the interest in youth activism prompted by the school strikes runs the risk of flattening global inequalities in young people’s exposure to environmental hazards, access to education and global knowledge networks. There is a need to look beyond such high-profile activities to understand how young people around the world are interpreting and responding to environmental concerns as generationally-positioned individuals operating within broader regimes of power.
Potent bioactive methanolic extract of wild orange (Citrus macroptera Mont.) shows antioxidative, anti-inflammatory, and antimicrobial properties in in vitro, in vivo, and in silico studies
Authors: Lala Mousikha , Modak Debabrata , Paul Subhashis , Sarkar Indrani , Dutta Ankita , Kumar Anoop , Bhattacharjee Soumen , Sen Arnab 
Published: May 2020

AbstractBackgroundThere is always an increasing demand for natural remedies from natural sources which can substitute the synthetic therapeutic drugs and lessen their side effects. The present study aims to investigate the antioxidant, anti-inflammatory, antimicrobial properties and in silico docking study ofCitrus macropteraleaf (CML) extract in both in vivo and in vitro aspect.Material and methodsThe antioxidant and anti-inflammatory potential of crude extract was investigated in vitro and in vivo on Wistar albino rat. The antioxidant potentiality also investigated on HepG2 cell line. Antimicrobial activity was evaluated againstStaphylococcussp. andKlebsiellasp. Chemical compounds of the crude extract were identified by GC-MS analysis. In silico docking was also done against NF-ҡB protein.ResultsAt 200 μg/ml concentration, CML significantly scavenges reactive oxygen species (ROS) which was generated on HepG2 cell line. CML showed 71% anti-inflammatory activity (p≤ 0.001) against carrageenan-induced paw edema in albino Wistar rats. CML extract is very effective againststaphylococcussp. thanKlebsiellasp. In the docking analysis, the proximadiol and menthone had − 5.6 kcal/mol and − 5.7 kcal/mol binding affinity with the protein NF-ҡB.ConclusionIn the present work, CML provided notable antioxidant, anti-inflammatory, and antimicrobial activity. This activity was confirmed by both in vitro and in vivo followed by in silico docking technique. Overall, the experimental results presented in this study suggest that crude extract of CML could be used as a promising antioxidant and anti-inflammatory candidate with potential benefits.
Ysla de Panciteria: a preliminary study on the culinary heritage significance of pancit using the heritage documentation approach—the case of Luzon Island, Philippines
Authors: Mercado Jame Monren T. , Andalecio Avi Ben P. 
Published: May 2020

AbstractPancitin the Philippines is known as one of the acculturated dishes of the Filipinos from the Chinese. Filipinos accepted the culinary tradition and became as one of the indigenized culinary identities. This qualitative study explicates the culinary heritage significances ofpancitin Luzon Island, Philippines using the Heritage Documentation Approach. From that context, this paper highlights the different kinds and variations ofpancitbased on cultural and heritage aspects of the community and its related characteristics such as the raw ingredients, selling points, cooking equipment, and tools; process of cooking, consumption, and the disposal and recycling of wastes. The researchers make use of different theoretical frameworks from international and national cultural charters and conventions. In the conduct of the research, the researchers used observation as the documentation process, which was based from the cultural heritage mapping. In-depth interviews were utilized to determine the perspectives of the major stakeholders specifically the local government units (LGUs) specifically the Tourism; and Culture and Arts Office; local culinary historians, owners of the restaurants or people who are known for practicing the culinary tradition; and the non-government organizations (NGOs) who are managing and safeguarding the culinary tradition. All of the gathered data were analyzed through the use of thematic analysis and repertory grid. Documentary evidences were assessed and analyzed to determine the perspectives of the previous and current researchers and authors. From the research, a total of 101 kinds ofpancitdishes were documented from 8 regions in Luzon. These were all differ from its characteristics and significances, but each dish contributes to the context of the community’s story and cultural value. In the end of the research, the researchers identified that the culinary tradition ofpancitin Luzon was developed based from regionalism, indigenization, and significance.
Generalized involute and evolute curves of equiform spacelike curves with a timelike equiform principal normal in $E_{1}^{3}$
Authors: Elsharkawy A. 
Published: May 2020

AbstractEquiform geometry is considered as a generalization of the other geometries. In this paper, involute and evolute curves are studied in the case of the curve α is an equiform spacelike with a timelike equiform principal normal vector N. Furthermore, the equiform frames of the involute and evolute curves are obtained. Also, the equiform curvatures of the involute and evolute curves are obtained in Minkowski 3-space.
Extending the applicability of a third-order scheme with Lipschitz and Hölder continuous derivative in Banach spaces
Authors: Sharma Debasis , Parhi Sanjaya Kumar 
Published: May 2020

AbstractWe extend the applicability of a cubically convergent nonlinear system solver using Lipschitz continuous first-order Fréchet derivative in Banach spaces. This analysis avoids the usual application of Taylor expansion in convergence analysis and extends the applicability of the scheme by applying the technique based on the first-order derivative only. Also, our study provides the radius of convergence ball and computable error bounds along with the uniqueness of the solution. Furthermore, the generalization of this analysis using Hölder condition is provided. Various numerical tests confirm that our analysis produces better results and it is useful in solving such problems where previous methods can not be implemented.