bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inheritance of wheat head productivity elements in F1 Triticum aestivum L. hybrids created on the basis of cultivars carring wheat-rye translocations 1AL.1RS and 1BL.1RS
Authors: Dubovyk N. S. , О. В. Гуменюк  , В. В. Кириленко  , Misiura I. I. , Т. М. Хоменко  
Published: December 2024

Purpose. Investigate the inheritance of the elements of productivity of the main ear-head by hybrids of the first generation of soft winter wheat, obtained from crossing varieties that carry wheat-rye translocations (WRT) 1BL.1RS and 1AL.1RS. Methods. Phenological, biometric, and statistical. Results. The differentiation of the elements of the crop structure between F1 hybrids was revealed. In 2016, based on the results of the analysis of the main ear length of F1 hybrids overdominance was detected in 26.7% of them, partial positive dominance – in 10.0%; by the number of grains: overdominance – in 13.3%, partial positive dominance – in 10.0%; by weight of grains from the main ear: overdominance – 16.7%, partial positive dominance – 3.3%. In 2017, overdominance along the length of the main ear was determined in 36.7% of the first generation hybrids, partial positive dominance – in 10%; by the number of grains: overdominance – 46.7%, partial positive dominance – 6.7%; by weight of grains from the main ear: over-domination – 40.0%, partial positive dominance – 10%. In terms of breeding ‘Kolumbiia’ / ‘Ekspromt’ (1AL.1RS / 1AL.1RS) crossing was the most valuable by the combination of the length of the main ear and the grain weight of it, hete­rosis was observed in 2016 and 2017; ‘Svitanok Myronivskyi’ / ‘Lehenda Myronivska’ (1BL.1RS / 1BL.1RS) showed good results in combination of the number and weight of grains from the main ear. The combination of two translocations in the wheat genotype can act as an auxiliary genetic background that increases the adaptive properties of the genotype to stressful environmental conditions and provides a high and constant level of grain productivity. Conclusions. A different degree of inheritance of grain product elements in wheat hybrids F1 was revealed. Hybrid combinations F1, which provided overdominance and partial positive dominance of the length, number and weight of grains of the main ear from crossing carrier cultivars carring WRT were identified. In terms of breeding ‘Kolumbiia’ / ‘Ekspromt’ (1AL.1RS / 1AL.1RS) crossing was the most valuable by the combination of the main ear length and the weight of grains, ‘Svitanok Myronivskyi’ / ‘Lehenda Myronivska’ (1BL.1RS / 1BL.1RS) – in combination of the number and weight of grains from the main ear.
Identifying the Role of Individual Seal IAPP Amino Acids in Inhibiting the Aggregation of Human IAPP
Authors: Menefee Kate , Larios Kelsy , Rinauro Dillon J. , Tun Angela , Jauregui Betssy , Contreras Jessica I. , Nogaj Luiza A. , Moffet David A. 
Published: December 2024

Introduction:
The progression of type 2 diabetes in humans appears to be linked to the
loss of insulin-producing β-cells. One of the major contributors to β-cell loss is the formation of
toxic human IAPP amyloid (hIAPP, Islet Amyloid Polypeptide, amylin) in the pancreas. Inhibiting
the formation of toxic hIAPP amyloid could slow, if not prevent altogether, the progression of
type 2 diabetes. Many non-human organisms also express amyloidogenic IAPP variants known to
kill pancreatic cells and give rise to diabetes-like symptoms. Surprisingly, some of these non-human
IAPP variants function as inhibitors of hIAPP aggregation, raising the possibility of developing
non-human IAPP peptides into anti-diabetic therapeutic peptides. One such inhibitory IAPP
variant is seal IAPP, which has been shown to inhibit hIAPP aggregation. Seal IAPP only differs
from hIAPP by three amino acids. In this study, each of the six seal/human IAPP permutations
was analyzed to identify the role of each of the three amino acid positions in inhibiting hIAPP aggregation.

Aims:
This study aimed to identify the minimal amino acid substitutions to yield a peptide inhibitor
of human IAPP aggregation.

Objective:
The goal of the study was to determine the minimal amino acid substitutions necessary
to convert human IAPP into an amyloid-inhibiting peptide.

Methods:
The formation of toxic hIAPP amyloid was monitored using Thioflavin T binding assays,
atomic force microscopy, and MTT cell rescue studies.

Results:
One seal IAPP variant retained amyloid-inhibition activity, and two variants appeared to
be more amyloidogenic and toxic than wild-type human IAPP.

Conclusion:
These results suggest that inhibition of hIAPP requires both the H18R and F23L substitutions
of hIAPP.
Development and Validation of a Literature Screening Tool: Few-Shot Learning Approach in Systematic Reviews
Authors: Wiwatthanasetthakarn Phongphat , Ponthongmak Wanchana , Looareesuwan Panu , Tansawet Amarit , Numthavaj Pawin , McKay Gareth J , Attia John , Thakkinstian Ammarin 
Published: December 2024

Background
Systematic reviews (SRs) are considered the highest level of evidence, but their rigorous literature screening process can be time-consuming and resource-intensive. This is particularly challenging given the rapid pace of medical advancements, which can quickly make SRs outdated. Few-shot learning (FSL), a machine learning approach that learns effectively from limited data, offers a potential solution to streamline this process. Sentence-bidirectional encoder representations from transformers (S-BERT) are particularly promising for identifying relevant studies with fewer examples.

Objective
This study aimed to develop a model framework using FSL to efficiently screen and select relevant studies for inclusion in SRs, aiming to reduce workload while maintaining high recall rates.

Methods
We developed and validated the FSL model framework using 9 previously published SR projects (2016-2018). The framework used S-BERT with titles and abstracts as input data. Key evaluation metrics, including workload reduction, cosine similarity score, and the number needed to screen at 100% recall, were estimated to determine the optimal number of eligible studies for model training. A prospective evaluation phase involving 4 ongoing SRs was then conducted. Study selection by FSL and a secondary reviewer were compared with the principal reviewer (considered the gold standard) to estimate the false negative rate.

Results
Model development suggested an optimal range of 4-12 eligible studies for FSL training. Using 4-6 eligible studies during model development resulted in similarity thresholds for 100% recall, ranging from 0.432 to 0.636, corresponding to a workload reduction of 51.11% (95% CI 46.36-55.86) to 97.67% (95% CI 96.76-98.58). The prospective evaluation of 4 SRs aimed for a 50% workload reduction, yielding numbers needed to screen 497 to 1035 out of 995 to 2070 studies. The false negative rate ranged from 1.87% to 12.20% for the FSL model and from 5% to 56.48% for the second reviewer compared with the principal reviewer.

Conclusions
Our FSL framework demonstrates the potential for reducing workload in SR screening by over 50%. However, the model did not achieve 100% recall at this threshold, highlighting the potential for omitting eligible studies. Future work should focus on developing a web application to implement the FSL framework, making it accessible to researchers.
Effect of Artificial Intelligence Helpfulness and Uncertainty on Cognitive Interactions with Pharmacists: Randomized Controlled Trial
Authors: Tsai Chuan-Ching , Kim Jin Yong , Chen Qiyuan , Rowell Brigid , Yang X Jessie , Kontar Raed , Whitaker Megan , Lester Corey 
Published: December 2024

Background
Clinical decision support systems leveraging artificial intelligence (AI) are increasingly integrated into health care practices, including pharmacy medication verification. Communicating uncertainty in an AI prediction is viewed as an important mechanism for boosting human collaboration and trust. Yet, little is known about the effects on human cognition as a result of interacting with such types of AI advice.

Objective
This study aimed to evaluate the cognitive interaction patterns of pharmacists during medication product verification when using an AI prototype. Moreover, we examine the impact of AI’s assistance, both helpful and unhelpful, and the communication of uncertainty of AI-generated results on pharmacists’ cognitive interaction with the prototype.

Methods
In a randomized controlled trial, 30 pharmacists from professional networks each performed 200 medication verification tasks while their eye movements were recorded using an online eye tracker. Participants completed 100 verifications without AI assistance and 100 with AI assistance (either with black box help without uncertainty information or uncertainty-aware help, which displays AI uncertainty). Fixation patterns (first and last areas fixated, number of fixations, fixation duration, and dwell times) were analyzed in relation to AI help type and helpfulness.

Results
Pharmacists shifted 19%-26% of their total fixations to AI-generated regions when these were available, suggesting the integration of AI advice in decision-making. AI assistance did not reduce the number of fixations on fill images, which remained the primary focus area. Unhelpful AI advice led to longer dwell times on reference and fill images, indicating increased cognitive processing. Displaying AI uncertainty led to longer cognitive processing times as measured by dwell times in original images.

Conclusions
Unhelpful AI increases cognitive processing time in the original images. Transparency in AI is needed in “black box” systems, but showing more information can add a cognitive burden. Therefore, the communication of uncertainty should be optimized and integrated into clinical workflows using user-centered design to avoid increasing cognitive load or impeding clinicians’ original workflow.

Trial Registration
ClinicalTrials.gov NCT06795477; https://clinicaltrials.gov/study/NCT06795477
Prevalence and Correlates of Diabetes Distress in Pregnant Individuals With Preexisting Diabetes: A Cross-Sectional Study
Authors: Tschirhart Holly , Usman Ali Muhammad , Yost Jennifer , Nerenberg Kara A. , Landeen Janet , Sherifali Diana 
Published: December 2024

OBJECTIVE
Managing preexisting diabetes during pregnancy requires considerable self-management skills to achieve recommended glycemic targets and reduce fetal and obstetrical risks. Given the demands during this time, many individuals may experience diabetes distress. This study aimed to determine the prevalence of diabetes distress and associated clinical factors of diabetes distress during pregnancy.

RESEARCH DESIGN AND METHODS
A cross-sectional study was conducted involving 36 pregnant participants with type 1 diabetes and 40 pregnant participants with type 2 diabetes. Assessments of diabetes distress, the primary outcome, were performed, along with assessments of depressive symptoms, self-efficacy, self-management, and patient care satisfaction. Linear and logistic regression analyses were conducted to determine predictors of diabetes distress scores and positive diabetes distress.

RESULTS
The prevalence of diabetes distress was 22.4%. Age ≥35 years of age and higher education levels were significantly associated with scores on the Problem Areas in Diabetes (PAID) scale, which measures diabetes-related emotional distress (decreases of 10.18 and 11.77 points, respectively, P = 0.04). Living with others was associated with a reduction in PAID score by 21.56 points (P = 0.05) and the Patient Assessment of Chronic Illness (PACIC) total score as well as PACIC goal-setting, and problem-solving/contextual counseling subscale scores were each associated with a decrease of ∼4 points in PAID score (P &lt;0.05). Having a common-law partner or spouse, comorbid depression, depressive symptoms, and depression scores were all significantly associated with increased PAID scores (P &lt;0.05).

CONCLUSION
The prevalence of diabetes distress in pregnancy is similar to estimates for nonpregnant adults with type 1 or type 2 diabetes, based on limited pregnancy literature. Further research is needed to establish diabetes distress rates using a validated tool for pregnancy to understand whether diabetes distress affects obstetrical and fetal outcomes and how diabetes distress levels can be alleviated in this population.
The Influence of the Principal's Transformational Leadership on Teacher Performance in Business Vocational Schools throughout Padang City
Authors: Fitri Aulia Rahma , Ermita  , Syahril  , Luthfiani  
Published: December 2024

This research aims to obtain data and information about 1) teacher performance, 2) principals' transformational leadership, 3) the influence of principals' transformational leadership on teacher performance in Business Vocational Schools throughout Padang City. The hypothesis proposed is that there is an influence of the principal's transformational leadership on teacher performance. This research is a quantitative descriptive research. With a population of 164 people and a sample determined using the Slovin formula of 66 people. The data collection tool used is a Likert scale model questionnaire which has been tested using simple linear regression data analysis techniques using the SPSS Version 29 program. The results of this research show that 1) teacher performance has been carried out well (85.00%), 2) transformational leadership the principal is already running (84.73%) and 3) there is a significant influence between the principal's transformational leadership on teacher performance in Business Vocational Schools throughout Padang City with a correlation coefficient of 0.119 and a correlation significance test of 2.670.
Nueva York-La Mancha: migración y transnacionalidad queer en la obra de Dionisio Cañas
Authors: González-Allende Iker 
Published: December 2024

Este artículo analiza la experiencia migratoria del poeta y artista Dionisio Cañas como hombre queer. Su migración a Nueva York en 1972, donde residió durante más de tres décadas, le posibilitó vivir libremente su sexualidad no-normativa, así como desarrollarse intelectual y profesionalmente. Al mismo tiempo, su poesía manifiesta una profunda nostalgia por La Mancha, su tierra natal, además de una visión crítica de la deshumanización de la ciudad de Nueva York. Con su retorno definitivo a La Mancha en 2005, Cañas desnaturaliza los discursos heteronormativos de la nación para adoptar una identidad transnacional que incluye tanto las realidades españolas como las estadounidenses, proclamando que se siente nómada y que su hogar no está conformado por un lugar geográfico concreto
Sexo y poder en la sociedad de clases. La política sexual interclasista en el imaginario literario de Juan Marsé
Authors: Aramburu Otazo Mikel 
Published: December 2024

Durante el tardofranquismo y la transición, Juan Marsé tematizó en varias novelas y relatos el acercamiento sexoafectivo entre jóvenes catalanas de acaudalada familia y hombres pobres inmigrantes. A diferencia de la interpretación reciente de estas obras, que ha favorecido una lectura en términos de la dialéctica nacional catalana, en este artículo se enfatiza el imaginario interclasista de estos (des)encuentros amorosos. Estas novelas pueden leerse como una expresión, al tiempo que una recreación, de lo que François Dubet (2019) denomina el “régimen de clases”, propio de la sociedad industrial, cuando la clase proporcionaba la principal cartografía social, del cual Marsé ofrece una particular versión caricaturesca y burlesca.
Characteristics of the process of tree mortality occurring in the Polish Sudetes Mts
Authors: Bruchwald Arkadiusz , Dmyterko Elżbieta , Chojnacka Ożga Longina , Sułkowska Małgorzata , Wrzesiński Piotr 
Published: December 2024

Abstract
The forests of the Sudetes Mts are among the ecosystems most threatened by climate change in Poland. Abiotic factors cause the threat, such as an increase in the average annual temperature and a clear change in the distribution of atmospheric precipitation intensity during the year. The aim of the study is to characterise the process of tree mortality, especially spruce, the main forest-forming species of the region, in the Sudetes.
The analyses carried out covered 12 forest districts belonging to the Regional Directorate of State Forests in Wrocław. Calculations made with the stand growth model showed that the total volume of merchantable timber in the forest districts is about 58 million m3, of which 68% consists of spruce. Two indices characterising the process of tree dieback, that is, tree dieback index (the volume of deadwood of a specific tree species harvested in the period 2011–2022) and tree dieback intensity coefficient (the quotient of the volume of deadwood harvested after the occurrence of the main cause of tree dieback and the volume of deadwood harvested before the occurrence of this cause there) were applied. The threat process intensified in 2015, when drought during the vegetation season caused massive thinning of trees and breakdown of tree stands, especially spruce stands and, to a lesser extent, pine and larch stands, and the least of all, birch, alder and beech stands. Therefore, it was assumed in the study that it is the ratio of the volume of deadwood obtained in the periods 2015–2018 and 2019–2022 to the volume of deadwood obtained in the period 2011–2014.
There is an urgent need to change the concept of forest management in Poland. In the field of silviculture, it should include in particular: a) planning the species composition of tree stands, adapted to the changing of their growth conditions; b) a critical approach to the methods of forest management, including harvesting system and c) a critical verification of the methods used to determine the action level of cutting management, especially harvesting systems, and the order of selection of tree stands for the implementation of these treatments.
Bacterial wetwood of Ulmus glabra Huds. in the relict coenopopulation of the Pokutsky Carpathians (Ukraine)
Authors: Kulbanska Ivanna , Goychuk Anatoliy , Soroka Myroslava , Plikhtyak Petro , Shvets Maryna , Pasichnyk Lidiya 
Published: December 2024

Abstract
In recent years, many abiotic and biotic factors have negatively impacted the health status of Ulmus glabra trees. Based on the syntaxonomic analysis of vegetation and a set of laboratory diagnostic studies, an attempt was made to isolate the catalysing factors and identify the causative agents of pathogenic processes that lead to the weakening and death of individuals of the U. glabra coenopopulation. The aim of the research was to evaluate the current health condition of trees of the relict coenopopulation of U. glabra, identify the factors of their weakening and dieback, study the pathogenesis and aetiology of the disease and experimentally confirm its causative agent.
Classical geobotanical and silvicultural, special microbiological (in particular, bacteriological analysis), mycological, and statistical research methods were used in the work.
Based on many years of research in the Pokutsky Carpathians, typical symptoms and signs of bacterial infection of U. glabra individuals resistant to Dutch elm disease were identified and described. It has been found that the current threat to old (100 or more years) U. glabra trees is a systemic vascular parenchymal disease known as bacterial wetwood. It has been studied that the drying of trees develops from the upper part of the crowns, and later, characteristic longitudinal cracks are formed on the trunks. In the active phase of the disease, there is a fountain-like release of exudate, and wet rot with a typical sour smell of fermentation appears. It was investigated and experimentally confirmed that, based on the signs of infection and the set of main characteristics, isolates of bacteria from the wood of diseased trees of U. glabra belong to the causative agent of the disease – the phytopathogenic bacterium – polybiotroph Lelliottia nimipressuralis (Carter 1945) Brady et al. 2013.
The influence of the type of root on the rooting of green roots of Viburnum opulus
Authors: Mazur Victor , Didur Ihor , Pantsyreva Hanna , Matusyak Mykhailo , Tysiachnyi Oleh 
Published: December 2024

Abstract
The conducted research is devoted to issues related to the propagation of rooted cuttings of common Viburnum opulus. As the research results indicate, significant death among rooted cuttings occurs during the propagation period. The purpose of the study was to investigate the effect of different types of cuttings on the rooting of the cuttings of Viburnum opulus during this researched period. It should be noted that the rooting success of the cuttings was high. The cuttings were collected from native Viburnum opulus mother plants under the conditions of the nebulizing installation of the winter garden of the «Podillia» Botanical Garden of the Vinnytsia National Agrarian University within the framework of the implementation of initiative topics at the Department of Forestry and Horticulture. According to the results of our research, the highest percentage of death among rooted Viburnum cuttings, across all studied varieties, was observed in the variant where the cuttings were grown at the rooting site. In this variant, significant death rates ranging from 18.7% to 35.4%, depending on the variety, occurred during the growing season. The reason for this is very small areas of nutrition and, accordingly, the thickening of plants. In contrast, when rooted cuttings are transplanted in autumn, death rates during overwintering range from 10.4% to 18.7%, with lower rates during transplanting and the growing season. During spring transplanting, the death of root plants is observed mainly during overwintering and transplanting, to a lesser extent during the growing season. Comparing the growth indicators of rooted cuttings planted in open ground and those grown in containers, it should be noted that there is a significant advantage in the development of the root system and the above-ground part in container-grown cuttings.
Public Administration Reconstruction and Development in Post-conflict States: A Critique of Global Trends and Experiences
Authors: Reddy Purshottama Sivanarain 
Published: December 2024

Abstract
The absence of peace, stability, and solidity in many states globally negatively impacts sustainable development, notably the Sustainable Development Goals (SDGs). The volatility and instability extend beyond the individual state and to neighboring states, not forgetting the region and continent. Weak/failed and post-conflict states are considered a possible danger and threat to universal safety. Consequently, their rebuilding and transformation should be prioritized in the broader international growth/development context. This viewpoint and thinking ushered in an international accord that conclusively decided that peace and stability are vital and indispensable for global development and are critical to the 2030 international growth and development framework. It was packaged and approved as an integral part of the SDGs in 2015 by the United Nations (UN). SDG 16 endorses sustainable development through peaceful/inclusive societies, developing efficacious inclusive/accountable structures at all governmental spheres and granting access to justice. SDG 16 alludes to sustainable development not being promoted and achieved without peace/harmony. Likewise, peace and harmony cannot be attained without sustainable development. In the context of collective growth/development and a global vision of “leaving no – one behind,” it is critical that good, robust post-conflict reconstruction and development is vigorously promoted with a view to a better life for all. The research methodology adopted for this paper was qualitative, as it included a desktop study of pertinent international and continental literature, including, among other things, books/chapters in books, journal articles and reports and other publications of the international donor community.