bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acquisition of multidrug-resistant Enterobacterales during international travel: a systematic review of clinical and microbiological characteristics and meta-analyses of risk factors
Authors: Voor in ‘t holt Anne F. , Mourik Kees , Beishuizen Berend , van der Schoor Adriënne S. , Verbon Annelies , Vos Margreet C. , Severin Juliëtte A. 
Published: May 2020

Abstract
Background
International tourism increased from 25 million tourist arrivals in 1950 to over 1.3 billion in 2017. These travelers can be exposed to (multi) resistant microorganisms, may become colonized, and bring them back home. This systematic review aims to identify the carriage rates of multidrug-resistant Enterobacterales (MDR-E) among returning travelers, to identify microbiological methods used, and to identify the leading risk factors for acquiring MDR-E during international travel.

Methods
Articles related to our research question were identified through a literature search in multiple databases (until June 18, 2019) - Embase, Medline Ovid, Cochrane, Scopus, Cinahl, Web of Science, and Google Scholar.

Results
Out of 3211 potentially relevant articles, we included 22 studies in the systematic review, and 12 studies in 7 random-effects meta-analyses. Highest carriage rates of MDR-E were observed after travel to Southern Asia (median 71%), followed by travel to Northern Africa (median 42%). Carbapenemase-producing Enterobacterales (CPE) were identified in 5 out of 22 studies, from a few patients. However, in only eight out of 22 studies (36.4%) the initial laboratory method targeted detection of the presence of CPE in the original samples. The risk factor with the highest pooled odds ratio (OR) for MDR-E was travel to Southern Asia (pooled OR = 14.16, 95% confidence interval [CI] = 5.50 to 36.45), followed by antibiotic use during travel (pooled OR = 2.78, 95% CI = 1.76 to 4.39).

Conclusions
Risk of acquiring MDR-E while travelling increases depending on travel destination and if antibiotics are used during travel. This information is useful for the development of guidelines for healthcare facilities with low MDR-E prevalence rates to prevent admission of carriers without appropriate measures. The impact of such guidelines should be assessed.
Use of social network analysis to examine preferential co-occurrences in Atlantic Sturgeon Acipenser oxyrinchus oxyrinchus Mitchill, 1815
Authors: Lilly Jessie , McLean Montana F. , Dadswell Michael J. , Wirgin Isaac , Comolli Perry , Stokesbury Michael J. W. 
Published: May 2020

AbstractBackgroundApplication of Social Network Analysis (SNA) to acoustic telemetry is a useful approach to examine social behavior in fish. Atlantic Sturgeon (Acipenser oxyrinchus oxyrinchus) are ancient, long-lived anadromous finfish. Although Atlantic Sturgeon have been the subject of numerous telemetry studies, none have used SNA to analyze their co-occurrence behavior. During 2010–2014 Atlantic Sturgeon (n = 103) that were later genetically identified as being from the Saint John River, Canada and the Kennebec River, US were captured by otter trawl and brush weir in Minas Basin, Bay of Fundy, Canada, and acoustically tagged. Using data from moored acoustic receivers within foraging habitat in Minas Basin, we tested if Atlantic Sturgeon formed social associations that were random or structured during 2012 to 2014; and whether these co-occurrences consisted of individuals from the same river of origin or capture date.ResultsIrrespective of genetic origin and initial capture date, Atlantic Sturgeon formed co-occurrences in Minas Basin that were significantly different than would be observed by chance during 2012 and very close to significant during 2013. Analysis demonstrated that some Atlantic Sturgeon preferentially co-occur within their primary feeding habitat.ConclusionsThe current threats to Atlantic Sturgeon aggregations within the Bay of Fundy, Nova Scotia, include bycatch in fisheries throughout their coastal migration routes and more recently the development of tidal turbines along their migratory corridor to their summer aggregation site. It is important to determine if Atlantic Sturgeon form aggregations with conspecifics from the same population to inform management decisions regarding threats to groups of individuals. This study indicated that Atlantic Sturgeon may form preferential co-occurrences within their feeding aggregation and co-occurrences that were identified were not dependent upon population of origin or initial capture date.
Measuring university students’ interest in biology: evaluation of an instrument targeting Hidi and Renninger’s individual interest
Authors: Knekta Eva , Rowland Ashley A. , Corwin Lisa A. , Eddy Sarah 
Published: May 2020

AbstractBackgroundBoosting students’ disciplinary interest has long been considered an important mechanism to increase student success and retention in STEM education. Yet, interest is a complex construct and can mean different things to different people, and many of the existing interest questionnaires do not identify a specific theoretical framework underlying their items. To demonstrate that curricular interventions targeting students’ interest are effective, educators need a theoretically based instrument to measure interest. The aim of this study was to develop an instrument measuring undergraduate students’ interest in the discipline of biology and collect initial validity evidence supporting the proposed use. The instrument structure is based on Hidi and Renninger’s (Educational Psychologist 41:111–127, 2006) conceptualization of individual interest, and the intended use is to evaluate changes in the biology interests of the US undergraduate students pursuing STEM degrees. To provide evidence of validity, the instrument was completed by 446 biology majors and 489 non-biology majors at two R1 universities. Exploratory and confirmatory factor analyses were applied to evaluate the internal structure of the instrument.ResultsThe final three-factor instrument supported by these analyses includes 6 items representing positive feelings towards biology, 5 items representing personal value of biology, and 8 items representing reengagement in biology-related activities. Measurement invariance across biology and non-biology majors was established and subsequent comparisons of these populations demonstrated that biology majors report significantly higher positive feelings, personal value, and reengagement in biology-related activities compared to non-biology majors.ConclusionsThe study findings support the use of the instrument to gain a broad understanding of students’ individual interest in biology. With minor adaptions, the instrument could also be evaluated for use in other STEM disciplines and for use by other populations.
Landslide susceptibility evaluation and hazard zonation techniques – a review
Authors: Shano Leulalem , Raghuvanshi Tarun Kumar , Meten Matebie 
Published: May 2020

AbstractLandslides are the most destructive geological hazard in the hilly regions. For systematic landslide mitigation and management, landslide evaluation and hazard zonation is required. Over the past few decades several techniques have been developed that can be used for landslide evaluation and zonation. These techniques can broadly be classified into qualitative and quantitative approaches. Qualitative approaches include geomorphological analysis and heuristic techniques whereas quantitative approaches include statistical, artificial intelligence and deterministic techniques. In quantitative techniques prediction for landslide susceptibility is based on the actual realistic data and interpretations. Further, the quantitative techniques also overcome the subjectivity of qualitative approaches. Each of these techniques may consider different causative factors and utilizes various means for factor evaluation and analysis. When compared, each of these techniques has its own advantage and disadvantage over other techniques. The selection of appropriate technique for landslide hazard evaluation and zonation is very crucial. The factors that need to be considered to adopt an appropriate approach are; investigation purpose, the extent of the area to be covered, the type of mapping units, the scale of map to be produced, type of data to be used, type of landslides, availability of resources, capability and skill set of an evaluator and the accessibility to the study area. The main aim of this article is to present a comprehensive review on various techniques and approaches available for landslide susceptibility and hazard zonation mapping. Further, attempt is also made to assess the effectiveness of these techniques in landslide hazard zonation studies.
When it all falls down: the relationship between intuitive physics and spatial cognition
Authors: Mitko Alex , Fischer Jason 
Published: May 2020

AbstractOur intuitive understanding of physical dynamics is crucial in daily life. When we fill a coffee cup, stack items in a refrigerator, or navigate around a slippery patch of ice, we draw on our intuitions about how physical interactions will unfold. What mental machinery underlies our ability to form such inferences? Numerous aspects of cognition must contribute - for example, spatial thinking, temporal prediction, and working memory, to name a few. Is intuitive physics merely the sum of its parts - a collection of these and other related abilities that we apply to physical scenarios as we would to other tasks? Or does physical reasoning rest on something extra - a devoted set of mental resources that takes information from other cognitive systems as inputs? Here, we take a key step in addressing this question by relating individual differences on a physical prediction task to performance on spatial tasks, which may be most likely to account for intuitive physics abilities given the fundamentally spatial nature of physical interactions. To what degree can physical prediction performance be disentangled from spatial thinking? We tested 100 online participants in an “Unstable Towers” task and measures of spatial cognition and working memory. We found a positive relationship between intuitive physics and spatial skills, but there were substantial, reliable individual differences in physical prediction ability that could not be accounted for by spatial measures or working memory. Our findings point toward the separability of intuitive physics from spatial cognition.
Mono and binuclear cobalt(II) mixed ligand complexes containing 1,10-phenanthroline and adenine using 1,3-diaminopropane as a spacer: synthesis, characterization, and antibacterial activity investigations
Authors: Abebe Atakilt , Bayeh Yosef , Belay Minale , Gebretsadik Tesfay , Thomas Madhu , Linert Wolfgang 
Published: May 2020

Abstract
Background
Coordination compounds, in particular cobalt(II) mixed ligand complexes containing 1,10-phenantroline, have drawn the attention of many investigators as some of them are showing antimicrobial activities.

Result
Herein, we report three novel mixed ligand complexes of cobalt(II) having the formulae [Co(L1)2(H2O)2]Cl2, [Co(L1)2(L2)(H2O)]Cl2 and [Co2(L1)4(L2)2(L3)]Cl4 (L1 = 1,10-phenanthroline, L2 = adenine, L3 = 1,3-diaminepropane) were synthesized and characterized by elemental analysis, conductivity measurement, infrared, and UV-Vis spectroscopic techniques. Octahedral geometries are proposed to all the complexes. In vitro antibacterial activities of the ligands, salt, and metal complexes were tested on four pathogenic bacteria (Staphylococcus aureus, Salmonella typhus, Escherichia coli, and Staphylococcus epidermis) using disc diffusion method.

Conclusions
It is interesting to note that the newly synthesized cobalt(II) complexes are active against gram negative bacteria (Escherichia coli and Klebsiella pneumoniae) even though cobalt(II) complexes are well known for their activity against gram positive bacteria.
Association of prior depressive symptoms and suicide attempts with subsequent victimization: analysis of population-based data from the Adult Psychiatric Morbidity Survey
Authors: Bhavsar Vishal , Hatch Stephani L , Dean Kimberlie , McManus Sally 
Published: May 2020

Abstract

Background:
Symptoms of mental disorder, particularly schizophrenia, predispose to victimization. Much less is known about the relationship between depressive symptoms and later victimization in the general population, the influence of these symptoms on types of subsequent victimization, or the role of symptom severity. We investigated this in nationally representative data from the United Kingdom.

Methods:
Data were from the Adult Psychiatric Morbidity Survey 2007. Multivariable logistic regressions estimated association between (a) prior depressive symptoms, (b) prior depressive symptoms with suicide attempt, and types of more recent victimization. Gender-specific associations were estimated using multiplicative interactions.

Results:
Prior depressive symptoms were associated with greater odds of any recent intimate partner violence (IPV), emotional IPV, sexual victimization, workplace victimization, any victimization, and cumulative victimization (adjusted odds ratio [aOR] for increasing types of recent victimization: 1.47, 95% confidence interval [CI]: 1.14, 1.89). Prior depressive symptoms with suicide attempt were associated with any recent IPV, emotional IPV, any victimization, and cumulative victimization (aOR for increasing types of recent victimization: 2.33, 95% CI: 1.22, 4.44). Self reported recalled data on previous depressive symptoms may have limited accuracy. Small numbers of outcomes for some comparisons results in imprecision of these estimates.

Conclusions:
Aside from severe mental illness such as schizophrenia, previous depressive symptoms in the general population are associated with greater subsequent victimization. Men and women with prior depressive symptoms may be vulnerable to a range of types of victimization, and may benefit from interventions to reduce this vulnerability.
Provider Recommendations for Phase I Clinical Trials Within a Shared Decision-Making Model in Phase I Cancer Clinical Trial Discussions
Authors: Hianik Rachel S. , Campbell Gavin P. , Abernethy Eli , Lewis Colleen , Wu Christina S. , Akce Mehmet , Dixon Margie D. , Shaib Walid L. , Pentz Rebecca D. 
Published: May 2020

PURPOSE:Debate continues over whether explicit recommendations for a clinical trial should be included as an element of shared decision making within oncology. We aimed to determine if and how providers make explicit recommendations in the setting of phase I cancer clinical trials.METHODS:Twenty-three patient/provider conversations about phase I trials were analyzed to determine how recommendations are made and how the conversations align with a shared decision-making framework. In addition, 19 providers (9 of whose patient encounters were observed) were interviewed about the factors they consider when deciding whether to recommend a phase I trial.RESULTS:We found that providers are comprehensive in the factors they consider when recommending clinical trials. The two most frequently stated factors were performance status (89%) and patient preferences (84%). Providers made explicit recommendations in 19 conversations (83%), with 12 of those being for a phase I trial (12 [63%] of 19). They made these recommendations in a manner consistent with a shared decision-making model; 18 (95%) of the 19 conversations during which a recommendation was made included all steps, or all but 1 step, of shared decision making, as did 11 of the 12 conversations during which a phase I trial was recommended. In 7 (58%) of these later conversations, providers also emphasized the importance of the patient’s opinion.CONCLUSION:We suggest that providers not hesitate to make explicit recommendations for phase I clinical trials, because they are able to do so in a manner consistent with shared decision making. With further research, these results can be applied to other clinical trial settings.
Foundation One Genomic Interrogation of Thyroid Cancers in Patients With Metastatic Disease Requiring Systemic Therapy
Authors: Iñiguez-Ariza Nicole M , Jasim Sina , Ryder Mabel M , Chintakuntlawar Ashish V , Morris John C , Hilger Crystal R , Menefee Michael E , Smallridge Robert C , Karlin Nina J , Alcaino Constanza , Bible Keith C 
Published: May 2020

Abstract

Context
Clinical applications of genomic assessment of thyroid cancers are rapidly evolving.

Objectives, Design, and Setting
We studied tumor samples from patients with imminently threatening and rare thyroid cancers to identify genomic alterations that might correlate with outcomes and/or be productively therapeutically targetable.

Patient Context
Progressive and metastatic, and/or rare, thyroid cancers were studied, 2012 to 2016, at Mayo Clinic sites.

Intervention
The intervention was Foundation One tumor interrogation.

Main Outcome Measures
Main outcome measures included genomic alterations, patient characteristics, and overall survival.

Results
Samples from 55 patients were evaluated: 20 anaplastic thyroid cancers (ATCs) (36%), 25 radioactive iodine–refractory differentiated thyroid cancers (DTCs)/poorly differentiated thyroid cancers (PDTCs) (45%; 14 papillary thyroid cancer [PTCs], 6 PDTCs, 5 Hürthle cell cancers), 8 medullary thyroid cancers (MTCs) (15%), and 2 others (a spindle epithelial tumor with thymus-like differentiation, and a primary thyroid sarcoma). Overall, 72% of DTCs, 79% of ATCs, and 75% of MTCs were deemed to have potentially productively targetable alterations. The most commonly encountered mutation was of TERT promoter (56% of DTCs, 68% of ATCs)—but this is not presently targetable. Targetable BRAFV600E mutations were found in 40% of DTCs/PDTCs (83% of PTCs) and 32% of ATCs; of MTCs, 75% had targetable RET mutations, and 25% HRAS mutations. Of patient tumors with nonmutated BRAFV600E, 53% of DTC/PDTCs and 69% of ATCs had other potentially productively targetable mutations. Genomic alterations in our series of poor prognosis metastatic DTC/PDTCs also closely resembled those seen in ATC.

Conclusions
Whereas genomic interrogation of favorable prognosis thyroid cancer seems ill advised, potentially productively targetable mutations were demonstrated in the majority of tumors from patients with metastatic thyroid cancers requiring systemic therapy, suggesting a rationale for the selective application of this technology.
Dynamically tunable reflecting near-infrared bandpass filter based on a hybrid graphene–nanometallic structure
Authors: Mirnia Seyed Edriss , Lail Brian A. 
Published: May 2020

A dynamically tunable reflecting near-infrared bandpass filter based on a hybrid graphene–nanometallic structure is demonstrated by numerical simulation. The proposed filter is constructed by unit cells with a graphene monolayer embedded into the nanometallic grating structure. The gradual transition of the graphene monolayer from a very thin metal to dielectric plays the key role in tuning the reflection spectrum of the structure. Spectral analysis clearly shows a passband blueshift with increasing graphene Fermi energy. The filter parameters are investigated by varying graphene Fermi energy through external voltage gates. The modulation depth, center frequency, bandwidth, and quality factor of the filter could be tuned. We achieved stable modulation depth as high as 0.735, and a quality factor as high as 3.4. The center frequency can be tuned in a broad range from 210 to 230 THz and with bandwidth tuning from 60 to 95 THz. The effect of the nanogap size and environment refractive index is also numerically investigated. These results are very promising for future use and integration of the proposed filters as a key element of optical communication systems and infrared sensing.
Widefield fluorescence localization microscopy for transcranial imaging of cortical perfusion with capillary resolution
Authors: Chen Zhenyue , Zhou Quanyu , Robin Justine , Razansky Daniel 
Published: May 2020

Imaging of cerebral vasculature is impeded with the existing fluorescence microscopy methods due to intense light scattering in living tissues and the need for highly invasive craniotomy procedures to resolve structures on a capillary scale. We propose a widefield fluorescence localization microscopy technique for high-resolution transcranial imaging and quantitative assessment of cortical perfusion in mice. The method is based on tracking single fluorescent microparticles sparsely distributed in the blood stream using a simple CMOS camera and a continuous-wave laser source. We demonstrate quantitative transcranial in vivo mapping of the blood flow velocity and direction at capillary level resolution (5 µm) across the entire cortex. The new technique opens a new high-resolution transcranial window into the brain function in health and disease.
All-fiber Mamyshev oscillator enabled by chirped fiber Bragg gratings
Authors: Boulanger Vincent , Olivier Michel , Guilbert-Savary Félix , Trépanier François , Bernier Martin , Piché Michel 
Published: May 2020

We present a linear cavity self-polarizing Mamyshev oscillator at 1550 nm made fully of polarization-maintaining fibers. The cavity filters are chirped fiber Bragg gratings with a Gaussian reflectivity profile that allow for greater reflectivity, larger bandwidth, and dispersion control. This mode-locked fiber laser architecture shows an unprecedented simplicity while delivering 21.3-nJ pulses compressed to 108 fs with a competitive 22.3% pump conversion efficiency. Mode locking is initiated with an external saturable absorber mirror. Numerical simulations show how nonlinearity can be managed with highly dispersive filters inside a Mamyshev oscillator.
Primeira classe: como construir uma escola de qualidade para o século XXI
Authors: Hickmann Adolfo Antonio , Hickmann Girlane Moura 
Published: May 2020

RESENHA
[SCHLEICHER, A. Primeira classe: como construir uma escola de qualidade para o século XXI. Tradução de Dani Gutfreund e Lenice Bueno. Paris: OECD Publishing; São Paulo: Fundação Santillana, 2019. Disponível em: <https://doi.org/10.1787/7475e4e1-pt.>. Acesso em: 14 ago. 2019.]