bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eales disease’ : etiopatogenesis dan tatalaksana
Authors: Zaini Lia Meuthia 
Published: December 2020

Abstrak. Eales disease merupakan kelainan vaskulopati obliteratif idiopatik primer, yang ditandai dengan adanya inflamasi pembuluh darah, oklusi, dan neovaskularisai pada retina, terutama mengenai pembuluh vena retina perifer. Kelainan ini pertama kali dideskripsikan oleh Henry Eales pada tahun 1882. Eales disease ditemukan di negara Inggris, Amerika, dan Kanada pada pertengahan abad ke-19 dan awal abad ke-20. Namun saat ini lebih sering ditemukan di negara India, dengan insidensi 1 dari 200-250 pasien dengan kelainan mata. Pada awal penyakit, beberapa pasien tidak menunjukkan gejala, namun yang lainnya menunjukkan gejala berupa adanya bintik-bintik yang melayang (floaters), serta pandangan kabur atau berkabut yang mungkin diakibatkan dari perdarahan vitreous.Terapi dengan kortikosteroid saat ini masih menjadi terapi utama dalam menangani vaskulitis yang terjadi pada retina. Beberapa tindakan lain yang juga dapat dilakukan adalah pemberian anti-VEGF, laser fotokoagulasi, penggunaan obat anti-tuberculosa, serta bedah vitreo-retina untuk mengatasi perdarahan vitreous yang terjadi. Kata kunci : Eales’disease, vaskulitis retina, tuberculosisAbstract. Eales disease is a primary idiopathic occlusive vasculopathy, characterized by venous inflammation (vasculitis), occlusion, and retinal neovascularization that usually involves the peripheral retina. This disease was first describe by Henry Eales in 1882. Eales disease was initially reported in United Kingdom, U.S.A, and Canada in the mid 19th century and the beginning of the 20th century. Now seen more commonly in the Indian, with the incidence was 1 in 200-250 ophthalmic patients. In the initial stages, some patients are often asymptomatic, but some may develop symptoms such as floaters and blurring vision due to vitreous hemorrhage. Corticosteroids remain the mainstay therapy to treat vasculitis in the retina. Others management are anti VEGF, laser photocoagulation, anti tuberculosis drugs, and vitreo-retinal surgery to manage unresolved vitreous hemorrhage. Key words: Eales’disease, retinal vaskulitis, tuberculosis
Mayer-Rokitansky-Küster-Hauser syndrome
Authors: Yeni Cut Meurah , Khairussani Khairussani , Bararah Wardatul 
Published: December 2020

Abstrak. Mayer–Rokitansky–Küster–Hauser syndrome (MRKH) adalah suatu sindrom yang ditandai dengan aplasia uterus, serviks, dan 2/3 vagina bagian atas karena perkembangan yang tidak sempurna dari duktus Mullerian. Dilaporkan seorang perempuan berusia 26 tahun yang mengeluh belum pernah menstruasi sampai saat ini. Secara fenotip pasien tampak sebagai perempuan yang memiliki perawakan normal. Payudara dan distribusi pertumbuhan rambut aksila serta kemaluan berkembang normal, disertai pertumbuhan lemak pada bokong dan paha. Tuba fallopi, rahim, dan vagina 2/3 proksimal tidak terbentuk. Pada pemeriksaan klinis ginekologi tampak introitus vagina dengan sonde vagina sepanjang 2 cm. Pemeriksaan USG abdominal, uterus berupa garis dan kedua ovarium sulit dinilai. Pemeriksaan MRI didapatkan agenesis uterus dan agenesis adnexa. Pemeriksaan analisa hormonal, LH 9,81 mIU/mL, FSH 6,87 mIU/mL, progesteron 0,51 ng/mL, estradiol 46,4 pg/mL, testosteron 60,45 mg/dl, TSH 1,216 mIU/L, T4 11 ug/dl, serta analisa kromosom 46XX. Pasien direncanakan untuk dilakukan vaginoplasti.Kata kunci : sindrom MRKH, anomali duktus Mulleri, vaginoplastiAbstract. Mayer–Rokitansky–Küster–Hauser syndrome (MRKH) is a syndrome characterized by uterine, cervix, and the two third of upper vagina aplasia which is the cause of incomplete development of the Müllerian duct. Reported a case of woman 26 years old, patient has not menstruated until now. The phenotype of the patient appears to be female, and with normal stature. Breast, axilla dan pubic hair distribution, fatty in buttocks and thigh developed normally. Fallopian tubes, uterine and 2/3 upper part of vagina were not formed. On gynecological clinical examination, found vaginal introitus with a vaginal sonde was 2 cm. On abdominal ultrasound examination, the uterus was seen as a line and both ovaries were difficult to assess. MRI examination obtained theresults as uterine and adnexa agenesis. Hormonal analysis showing LH 9.81 mIU/mL, FSH 6.87 mIU/mL, progesteron 0.51 ng/mL, estradiol 46.4 pg/mL, testosterone 60.45 mg/dl, TSH 1.216 mIU/L, T4 11 ug/dl, and chromosome examination is 46 XX. Patient are planned for vaginoplasty. Key words: MRKH syndrome, mullerian duct anomalies, vaginoplasty
Peran pemeriksaan radiologis pada diagnosis Coronavirus disease 2019
Authors: Yanti Budi , Hayatun Ulfa 
Published: December 2020

Abstrak. Coronavirus Disease 19 (COVID-19) telah menjadi pandemi di seluruh dunia dengan angka kejadian yang terus meningkat di beberapa negara. Kecepatan dan ketepatan diagnosis diperlukan untuk mencegah perburukan kondisi pasien. Real-Time Transcription Polymerase Chain Reaction (RT-PCR) sampai saat ini masih menjadi baku emas untuk menegakkan diagnosis COVID-19, namun uji diagnostik ini dilaporkan banyak menunjukkan hasil negatif palsu. Pemeriksaan radiologi berupa foto toraks dan CT-Scan dada banyak dilakukan untuk menunjang diagnosis COVID-19. Gambaran foto toraks yang paling sering ditemukan adalah konsolidasi, ground-glass opacity (GGO), distribusi bilateral, perifer dan di lobus bawah paru-paru, namun pemeriksaan ini dianggap tidak sensitif untuk menemukan kelainan paru pada tahap awal penyakit. Meskipun demikian, foto toraks dapat digunakan untuk memantau perkembangan kelainan paru akibat COVID-19, salah satunya dengan metode Brixia Score. Pada sisi lain,CT-scan dada dinilai lebih sensitif daripada foto toraks serta mampu menunjukkan kelainan paru tahap awal pada pasien dengan hasil RT-PCR yang negatif. Gambaran pada CT-scan dada umumnya menunjukkan GGO, konsolidasi, crazy-paving stone, dan air bronchogram. CT-scan dapat mengurangi angka negatif palsu pada RT-PCR dan sebagai alat skrining pada pasien yang dicurigai COVID-19 di lokasi epidemis saat hasil RT-PCR tidak tersedia. Penggunaan pemeriksaan radiologi dan RT-PCR dapat menghemat waktu serta membantu diagnosis dan manajemen COVID-19. Kata Kunci: Pencitraan COVID-19, Radiologi SARS-CoV-2Abstract. Coronavirus Disease 19 (COVID-19) has become a worldwide pandemic with an increasing incidence in several countries. Speed and accuracy of diagnosis are needed to prevent worsening of patient's condition. Real-Time Transcription Polymerase Chain Reaction (RT-PCR) is still a gold standard of COVID-19 diagnosis, however, this test shown false negative results in several case. Radiological examinations, chest X-Ray (CXR) and CT scan, are used to support the diagnosis. The most commonly found in CXR are consolidation, ground-glass opacity (GGO), bilateral distribution, peripheral and in the lower lobe, but this examination is insensitive to find lung abnormalities in early stages of disease. However, CXR can be used to monitor the development of lung abnormalities due to COVID-19, such as the Brixia Score method. On the other hand, CT-Scan is more sensitive than CXR and able to show early lung abnormalities in negative RT-PCR results. CT scan show the presence of GGO, consolidation, crazy-paving stone, and air bronchogram. CT-scanning can reduce the false-negative rate on RT-PCR and become a screening tool in suspected COVID-19 patients at epidemic area where RT-PCR is not available. The use of radiological examinations and RT-PCR can save the time and help in the diagnosis and management of COVID-19.Keywords: COVID-19’s Radiology, Imaging of SARS-CoV-2
Pemantauan trauma kepala pada anak
Authors: Ismy Jufitriani 
Published: December 2020

Abstrak. Trauma kepala pada pada anak dapat terjadi akibat pukulan, jatuh, benturan maupun hentakan mendadak. Trauma kepala ringan salah satu kasus tersering di bagian neurologi anak. Trauma kepala dapat menyebabkan cedera kepala dan penyebab kematian terbanyak pada anak. Perbedaan dari segi anatomi, fisiologi, serta metabolisme pada anak dan dewasa sehingga pada anak lebih mudah untuk mengalami cedera kepala dibandingkan dengan orang dewasa. Pemantauan saat terjadinya trauma dan pemantauan jangka panjang diperlukan untuk mendeteksi secara dini kelainan perkembangan anak.Kata kunci: Trauma kepala anak, cedera kepala, pemantauan Abstract. Head trauma in children can occur due to blows, falls, collisions or sudden shocks. Mild head trauma is one of the most common cases in pediatric neurology. Head trauma can cause head injuries and is the leading cause of death in children. Differences in terms of anatomy, physiology, and metabolism in children and adults make it easier for children to experience head injuries than adults. Monitoring when trauma occurs and long-term monitoring is needed to detect early childhood developmental abnormalities. Key words: head trauma in children, head injury, follow up
Profil hematologi mencit (Mus musculus L.) strain Balb/c jantan akibat paparan asap rokok elektrik
Authors: Utami Eva Tyas , Risqillah Ulfi , Fajariah Susantin 
Published: December 2020

Electronic cigarette is one type of cigarette that are popular. This is because of the nicotine content in electronic cigarette liquid that can be regulated by the user so it is considered safe. The purpose of this study was to analize electronic cigarette effect on hematology profile of male Balb’C mice (Mus musculus L). This study used 24 males mice which were divided into 4 groups. Group 1 (control) was the group without electronic cigarette exposure. The group 2,3, and 4 were exposed to electronic cigarette for 1 ml, 2 ml and 4 ml liquid respectively. This study use liquid that containing 6 mg nicotin/ml. The exposure to electronic cigarette were conducted for 4 weeks. Hematology profile observation include hemoglobin level, erytrocytes count, count and types of leukocytes.The result showed that hemoglobin level and erytrocytes count was increase, leukocytes and lymphocyte count was decrease and no effect on granulocytes and MID after electronic cigarette exposure using different liquid volume. The conclusion of this study was electronic cigarette exposure with different liquid volume as long as four weeks affect to Balb’C male mice hematology profile.
AKTIVITAS EFFECTIVE MICROORGANISMS (EM) DALAM TANAH PERTANIAN ORGANIK YANG TERPAPAR KLORPIRIFOS
Authors: Rizkiyanti D. , Wirajana I N. , Suyasa I W. B. 
Published: December 2020

One way to restore soil fertility exposed to pesticides such as chlorpyrifos is by bioremediation using Effective Microorganisms (EM). The purpose of this study was to determine EM microbial resistance and chlorpyrifos degrading enzyme activity in organic farming soil sample.The organic farming soil sample used previously has been exposed to EM for a long time. This soil sample was divided into two treatments, namely sterilized by autoclaving and not sterilized (thus indigenous microbes remain alive). The next two soil samples were with and without addition of EM with incubation time of 3, 5, and 7 days. The results of this study indicated that EM microbes could withstand exposure to chlorpyrifos to a concentration of 56 ppm. The phenomenon of chlorpyrifos degrading enzyme activity was found in sterile soil samples with EM addition of 0.017 U/mL during 7-day incubation with a decrease in chlorpyrifos levels of 16.65%. The highest activity of chlorpyrifos degrading enzyme was found in unsterile soil sample, which amounted to 0.039 U/mL during the 3-day incubation period with a decrease in chlorpyrifos levels of 74.11%. The highest decrease in chlorpyrifos was found in unsterile soil sample by 80.04% with an incubation time of 5 days.
Keywords: chlorpyrifos, bioremediation, microbial EM (Effective Microorganisms)
SINTESIS MEMBRAN NATA DE PINA DAN APLIKASINYA UNTUK ADSORPSI ZAT WARNA TEKSTIL REMAZOL RED RB
Authors: Sukarta I N. 
Published: December 2020

This study utilized pineapple peel waste into a membrane of nata de pina and used as an adsorbent for remazol red RB. The purpose of this study was to synthesis nata de pina membranes, determine the optimum pH, concentration and contact time of adsorption, isotherm pattern, and the maximum adsorption. The results indicated that cellulose nata de pina membranes were successfully synthesized and had the potential to become adsorbents for absorbing remazol red RB dyes. FTIR results showed that membrane nata de pina was a cellulose based membrane with swelling test result of 187.9%. The optimum conditions were at pH 2 with adsorption capacity of 17.12 mg/g, concentration of 80 mg/L with absorption capacity of 22.36 mg/g and contact time at 120 minutes with absorption capacity of 25.29 mg/g. The adsorption of remazol red RB dye has fulfilled the pattern of Langmuir adsorption isotherm with maximum adsorption of 0.0219 g/g or 21.9 mg/g adsorbent.
Keywords: Adsorption, Nata de pina, membrane, Remazol red RB
OPTIMASI PROPILENGLIKOL DALAM FORMULASI SIRUP EKSTRAK RIMPANG JAHE SEBAGAI OBAT BATUK
Authors: Artania A. I. , Harta I K. G. G. G. , Pratama G. W. A. P. , Ayu N. P. A. S. , Sukmarani I. G. A. P. , Arisanti C. I. S. 
Published: December 2020

Ginger (Zingiber officinale) has a pharmacological effect to be an antitussive which has been proven empirically and through in vivo activity testing. The use of ginger directly has a spicy and bitter taste, so it is not very popular. Based on this, it is necessary to formulate it into syrup preparation which has met the physical stability test to obtain the best formula. In this study, ginger rhizome water extract that had been standardized and screened was formulated into syrup preparations. The formulation was carried out by optimizing the amount of propylene glycol as co-solvents and anti-cap locking which was 15, 20, and 25% of syrup preparation. The results showed that the concentration of propylene glycol in ginger rhizome extract syrup preparation affected the physical stability of the preparation. The three formulas obtained have not met the physical stability tests (pH and viscosity), but formula 3 with 25% of propylene glycol was the optimum formula of ginger rhizome syrup.
Keywords: Antitussives, Ginger (Zingiber officinale), Syrup, Propylenglycol, Viscosity
Rimpang jahe (Zingiber officinale) memiliki efek farmakologi sebagai antitusif yang telah dibuktikan secara empiris dan melalui uji aktivitas secara in vivo. Penggunaan jahe secara langsung memiliki rasa pedas dan getir sehingga tidak begitu disukai. Berdasarkan hal tersebut maka perlu diformulasikan ke dalam sediaan sirup yang telah memenuhi uji kestabilan fisik untuk memperoleh formula terbaik. Pada penelitian ini, ekstrak air rimpang jahe yang telah terstandar dan telah dilakukan skrining diformulasikan menjadi sediaan sirup. Formulasi dilakukan dengan optimasi jumlah propilen glikol yaitu 15, 20, dan 25% sebagai kosolven dan anti-caplocking terhadap sediaan sirup. Hasil yang diperoleh adalah konsentrasi propilenglikol dalam sediaan sirup ekstrak rimpang jahe berpengaruh terhadap stabilitas fisik sediaan. Tiga formula yang dikerjakan belum memenuhi persyaratan uji kestabilan fisik, namun formula 3 dengan 25% propilen glikol merupakan formula terbaik dari sirup rimpang jahe.
Kata kunci: Antitusif, Rimpang jahe (Zingiber officinale), Sirup, Propilenglikol, Viskositas
Pengaruh Aktivitas Eksklusif Sempadan Pantai Bagi Kehidupan Masyarakat Di Pantai Double-Six
Authors: Handayani Gracia Luciana , Sanjiwani Putri Kusuma 
Published: December 2020

The tourism sector has a lot of impact on the economy of Badung Regency, especially in the Province of Bali even though, the ongoing activities of exclusive beach borders that are used for public spaces cannot yet be tolerated.As for the scope of the research, there are exclusive activities carried out by tourism entrepreneurs in the area of ??the beach that are used for exclusive activities, such as: tourist activities, community activities, activities of businesses in the field of tourism, viewpoints of tourists, viewpoints of people who live in villages. Seminyak customary, along with the regency-Badung regulations regarding exclusive activities on the coastline at DTW Double-Six Beach. techniques in collecting data in this study include observation, interviews, literature studies, and also documentation. The purposive sampling method is the technique of determining the informants used. The technique used in the cultivation of the report is a qualitative descriptive analysis. Exclusive activities at Sempadan Pantai carried out by tourism entrepreneurs include: K-Resto, Blue9Beach, The Sand Beach Bar&Grill, Capil Beach Grill&Bar, D’Joglo Beach Bar&Restaurant, The-Camplung Bar&Restaurant, La-Plancha, Bali Juice-Park, Taris-Bali, dan Chiringuito Bar-Grill- Restaurant. This exclusive activity also gives effect to the people who live around the Smeinyak Indigenous Village community, among others in terms of language, how to dress, building a business place, music flow, food and drink, and so forth. Tourism that comes is also presented with attractions that are present / modern

eyword: exculsive activity, impact, beach border, public area, double six beach
Strategi Pemasaran Wisata Kuliner Sebagai Destinasi Wisata Di Dili, Timor-Leste
Authors: Nheu Grace Deo Seldudes Eta , Sugiarti Dian Pramita 
Published: December 2020

These project are done for discussing the culinary tourist marketing at the tourism industry by identifying some of East Timor’s traditional foods that could be developed as a culinary destination. Local culinary has a good potential to be developed and can be used as a tourist product to attract tourist for a pay visit in East Timor by the reason of foods and drinks diversity and in East Timor. The purpose of this project is to know the culinary tourist marketing as a tourism business and attract tourists in Dili, East Timor. Data gathering techniques which is used to collects in this project are observation, interview, and documentary studies and this project using primary and secondary data. The study also employs qualitative data and will be analysis with qualitative techniques methods of marketing and is made up on four (4p) marketing structure. In this project has been used concepts that are related like marketing strategies, the culinary tours, the traditional foods, tourist destination, gastonomic theory, and marketing theory. The conclusion on these research are to discover certain local culinary potential that have been exploited as a culinary tourist destination. Tourist marketing that could developed tradional foods from East Timor should be give to East Timor’s sustainability.
Keywords : Marketing Strategies, Culinary Tourism, Traditional Food.
Upaya Dinas Pariwisata Ternate Dalam Mengatasi Penurunan Kunjungan Wisatawan Di Daya Tarik Wisata Pantai Sulamadaha
Authors: Fabanyo Ayu Astrid , Sastrawan I Gede Anom 
Published: December 2020

This study aims to determine the factors that cause a decrease in tourist visits and efforts made by the Ternate City Tourism Office in overcoming the decreasing intensity of tourist visits in Sulamadaha Beach Tourism Attractions. Ternate located in North Maluku Province. Ternate is one of 10 districts in North Maluku Province that have many tourist attractions, for example Sulamadaha Beach. Sulamadaha Beach is an attraction that is managed directly by the Ternate City Tourism Office and the local community, Sulamadaha Beach has beautiful underwater natural beauty, according to data from the Ternate City Tourism Office Sulamadaha Beach is the most popular destination for tourists, but this does not last long as it is known from the data of tourist visits that Sulamadaha Beach every year has decreased, related to this, it will be research about "The efforts of the City of Ternate Tourism Office in Overcoming the Decreasing Intensity of Tourist Visits in Sulamadaha Beach Attractions"
The research method used in this study is the type of research is descriptive research with a qualitative approach. The results of this study indicate that there are several factors that cause a decrease in the intensity of tourist visits in Sulamadaha Beach Tourism by using the concept of Sapta Charms, namely safe factors, orderly factors, and friendly factors, Ternate City Tourism Office has also designed several programs to stabilize the problem. One of the efforts made by the agency is to add supporting facilities to tourist attractions.
Keywords :efforts, decline
Analisis Potensi Ekowisata dan Kesiapan Masyarakat Desa Rendu Tutubadha dalam Pengembangan Ekowisata
Authors: Aja Adriano Filemon , Arida I Nyoman Sukma 
Published: December 2020

Tourism trend and tourist motivation changes dynamically since the first time development of tourism. Mass tourism is one of tourism trend which grow Praccessibility, etc) and tour with a big group. Ecotourism appears in the early of 1990, ecotourism can be defined as a responsibility journey to a natural place. The aim is to make empowerement in the local society, conservancy, and the preservation of local society’s culture. Ecotourism grows fastly because this trend is different from conventional tourism which dominates. Rendu Tutubadha village locates in Aesesa District, Nagekeo Regency, East Nusa Tenggara Province has a big potential of ecotourism. Ecotourism potentials in this village consists of natural hot spring of Ae Petu Meze, Lambo Mountain, traditional village and etu ritual. Develop these ecotourism potentials needs readiness of Rendu Tutubadha’s society so the development will hold by the ecotourism principals and give positive effect to the society in eceonomis and other aspect. This research using primary and secondary data, quantitative and qualitative data is also used in this research. Data collecting method is interview, literature study, and observation. Qualitative descriptive used to presents the research result. This research finds some ecotourism potenstials in Rendu Tutubadha village. The ecotourism potential is nature and culture potential. The nature potential is like natural hot spring of Ae Petu Meze and Lambo Mountain, besides of that there are two culture potentials like traditional village of Rendu Tutubadha and Etu ritual. This research also finds that Rendu Tutubadha’s society readiness is enough to develop ecotourism, it can be seen in the society’s traditional life, although there are some aspects of ecotourism needs to fixed
Keyword: ecotourism potential, ecotourism, society readiness
Partisipasi Masyarakat Lokal Dalam Pengelolaan Daya Tarik Wisata Air Terjun Sipiso-piso Kabupaten Karo, Sumatera Utara
Authors: Sitanggang Louis Steven , Sugiarti Dian Pramita 
Published: December 2020

Sipiso-piso Waterfall located in Karo District, North Sumatra can be used as a superior attraction because it has great potential to be developed compared to other attractions around Lake Toba because this waterfall is one of the most popular tourist attractions. However, there are several obstacles on the development of Sipiso-piso Waterfall tourism such as tourism stakeholders who do not cooperate well such as the provision of supporting facilities that should be provided by the tour manager, namely the Karo District government instead, provided by the local community. Based on this phenomenon, it is necessary to know the management of Sipiso-piso Waterfall and how much participation of local people in the management of Sipiso-piso Waterfall.
The method used in this research is descriptive qualitative. This research aims to To find out how to manage Sipiso-piso waterfall in Karo District, North Sumatra To find out how far the participation of local people in the management of Sipiso-piso waterfall. Data collection techniques using observation, interviews, and literature. Determination of informants using Purposive Sampling techniques. The results of this research is that the community in the management of Sipiso-Piso Water Tourism Attraction at the planning stage is at the encouraged participation type, at the community organizing stage is at the spontaneous participation as well as at the mobilization stage, while at the community supervision stage is at the encouraged participation type.

Keywords: participation, development, local community