bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular genetic characteristics of hemostasis in hemorrhagic fever with renal syndrome
Authors: Manakhov K M , Sarksyan D S , Dudarev M V , Tolstoluckaya T O , Ponomarenko N S , Maleev V V 
Published: December 2020

Aim. To assess the predictive value of single-nucleotide polymorphisms of hemostasis and folate cycle genes in hemorrhagic fever with renal syndrome (HFRS).
Methods. 43 patients undergoing HFRS were examined based on the Republican clinical infectious diseases hospital in Izhevsk. Toxic shock syndrome (TSS) in the decompensated phase, pulmonary edema in the alveolar phase, and acute kidney injury (AKI) at stage F [RIFLE criteria (risk, injury, failure, loss, end-stage renal disease)] were registered as complications. Molecular analysis of patients genomic DNA was performed after its isolation from peripheral blood cells. Genotyping was performed by using multiplex real-time PCR with conformationally restricted probes. Statistical analysis was performed by the licensed program SPSS 22.0; the significance level of difference between groups was determined using the nonparametric MannWhitney test (for quantitative variables) and the Fishers exact test (for qualitative variables).
Results. The C/C genotype of the ITGB3:1565T/C gene (p=0.0278), and the C/C genotype of the MTHFR1298 A/C gene (p=0.0407) was less common in severe cases, while the G allele of FGB:455G/A gene (p=0.046) and the T allele of the ITGB3:1565T/C gene (p=0.0166) was more frequent. More frequent detection of the 5G/4G genotype of the PAI-1:675 5G/4G gene was found in the case of TSS (p=0.0433). Genotype C/C of the ITGB3:1565T/C gene (p=0.0145) and a combination of pathological genotypes A/C and C/C of the MTHFR1298A/C gene (p=0.0004) are less common in the development of AKI at stage F.
Conclusion. The molecular genetic analysis makes it possible to identify patients with genotypes predisposing to a severe and complicated course of hemorrhagic fever with renal syndrome.
Scientific substantiation of the assessment of the territorial availability of primary medical health care to the rural population
Authors: Kalininskaya A A , Bayanovа N A 
Published: December 2020

Aim. To assess the territorial accessibility of primary health care (PHC) to the rural population in the Orenburg region.
Methods. Statistical, monographic, organizational experiment research methods were applied. Statistical processing was carried out by using the Statistica 10.0 software. Basic statistics were calculated (arithmetic mean, weighted arithmetic mean). All parameters were checked by using ShapiroWilk, KolmogorovSmirnov and Lilliefors tests for normal distribution. The parametric method of statistics (Student's t-test) was used.
Results. The assessment of the territorial accessibility of primary medical health care to the population of the Orenburg region was carried out using the methodology developed by us for calculating the criteria for the accessibility of primary medical health care to the rural population Rating of medical organizations according to the criterion of territorial accessibility of primary medical care to the rural population. The use the methodology allows making management decisions regarding the territorial planning of primary health care for the rural population in the selection of problem areas with low accessibility of primary medical care. In the Orenburg region, there are the following problems: different levels of accessibility of primary health care with a variety of distance up to 30 km and different population sizes in settlements create difficulties in organizing the provision of primary health care; remoteness from the regional center up to 300 km forms a personnel deficit.
Conclusion. Application of the methodology Rating of medical organizations according to the criterion of territorial accessibility of primary medical care to the rural population in the Orenburg region has allowed the development of the following recommendations for making management decisions at the regional level: (1) prioritization of territories for priority measures to ensure the availability help; (2) selection of the form of primary health care organization for the timely medical care provision to the population; (3) the formation of competition among medical organizations in the ranking of the availability of primary health care.
Comparative characteristics of computed tomography and radiography in the diagnosis of blunt chest trauma
Authors: Gasimzade G Sh 
Published: December 2020

Aim. To conduct a comparative analysis of the effectiveness of X-ray diagnostics and computed tomography in detecting injuries in patients with blunt chest trauma.
Methods. We examined 68 patients with chest injuries (men and women) and an average age of 34.67 years (between 18 and 65 years). The causes of injury were: road accidents 37 (54.4%), falls from a height 21 (30.8%), blunt blow to the chest 10 (14.8%). The results of X-ray and computed tomography examination of patients were compared.
Results. X-ray examination revealed a chest bone fracture in 24 (35.3%) patients, while computed tomography revealed a bone fracture in 32 (47.1%) cases (2=1.943; p=0.163). This allows us to state that the results of computed tomography scans are more accurate in the diagnosis of chest fractures. computed tomography scan revealed chest injuries pneumothorax and hemothorax, in 56 (82.4%) cases, while X-ray examination in 37 (54.4%) cases (2=12.277; p 0.001). Thus, the results of the study showed that computed tomography is a more informative method of diagnosis compared to radiography, since computed tomography revealed 11.8% more cases of chest bones fractures, and 28.0% more cases of chest cavity damage with blunt trauma.
Conclusion. Our study allows us to recommend computed tomography of the chest in blunt trauma as the initial preferred diagnostic radiology.
The Worship of Divine Mercy in Light of the Teaching of Pope Benedict XVI and Pope Francis
Authors: Lancton Thaddaeus 
Published: December 2020

Kult Miłosierdzia Bożego w świetle nauczania papieża Benedykta XVI i papieża Franciszka
Dwaj ostatni papieże, Benedykt XVI i Franciszek, wzorem Jana Pawła II, akcentują w swoim nauczaniu Miłosierdzie Boże. Każdy z nich czyni to inaczej, a w związku z tym sposób oddawania czci Bożemu Miłosierdziu będzie u nich inny. Podczas gdy obydwaj papieże akcentują całość historii zbawienia, w której objawia się Miłosierdzie Boże, uwieńczone w osobie Jezusa Chrystusa, papież Franciszek częściej mówi o praktyce miłosierdzia i unika teoretyzowania. Jednym ze sposobów urzeczywistniania miłosierdzia jest propozycja dodania do różańca nowych tajemnic, które nie mają wsparcia w papieskim nauczaniu Benedykta XVI, ale znajdują poparcie w pragnieniu papieża Franciszka, by coraz bardziej przenikało ono do codziennych postaw i działań chrześcijan. Należy zadbać, aby wpisać taką zmianę sposobu oddawania czci Bożemu Miłosierdziu wraz z właściwym uzasadnieniem teologicznym, podkreślającym obecność Miłosierdzia Bożego w istniejących już tajemnicach różańca, zwłaszcza we Wcieleniu i Tajemnicy Paschalnej.
Democracia e esfera pública no mundo digital
Authors: Bernardo de Oliveira Cristina Godoy , Silva Rafael Meira 
Published: December 2020

O objetivo central é identificar os desafios do direito nas próximas décadas no que concerne à inclusão digital e à formação de um espaço público virtual. Dessa forma, neste artigo de revisão, será analisada a desigualdade no que se refere ao acesso à novas tecnologias de comunicação e à internet, sendo que denominaremos esta segregação de divisão digital, a qual é subdividida em: divisão global, divisão social e divisão democrática. Assim, o problema-chave é relativo à viabilidade de se garantir a democracia em um ambiente desigual no que se refere ao acessso à informação dismonível na internet. Trata-se de uma pesquisa bibliográfica, empregando-se o método analítico para analisar os dados auferidos e os argumentos doutrinários apresentados na pesquisa. Além disso, ao se estudar a questão concernente aos discursos de ódio e à invasão da privacidade, cumpre-se destacar o emprego do método monográfico. Em um primeiro instante, será verificada a questão relativa ao desequilíbrio existente entre os países no que tange à penetração da internet e ao acesso à informação, notando-se que o abismo entre países pobres e ricos pode ser ampliado se esta diferença intensificar-se. Em segundo lugar, analisar-se-á a problemática relativa à divisão social, que diz respeito ao desequilíbrio quanto ao acesso à informação e à internet no âmbito de cada país. O fortalecimento da educação torna-se instrumento fundamental para que o Brasil supere a divisão social, visto que não basta fornecer acesso à internet, é necessário o preparo dos cidadãos para se beneficiarem das infinitas informações existentes. A divisão democrática torna-se um desafio importantíssimo à justiça constitucional, em razão da relevância de se estabelecer parâmetros para a ponderação entre a liberdade de expressão e a invasão de privacidade/discursos de ódio. O espaço público virtual apenas efetivar-se-á quando não existir a divisão digital, logo, é preciso fortalecer e criar instrumentos jurídicos garantidores da democracia em uma Era da Informação.Por conseguinte, constatou-se que, no Brasil, a divisão digital é uma realidade e afeta a construção de um espaço democrático no ambiente digital em que o discurso seja de cidadãos dirigindo-se a outros cidadãos em situação de igualdade.
Andrade, Nathanael J. (2018). The Journey of Christianity to India in Late Antiquity. Networks and the Movement of Culture
Authors: Ferrara Marianna 
Published: December 2020

ANDRADE, NATHANAEL J. (2018). The Journey of Christianity to India in Late Antiquity. Networks and the Movement of Culture. Cambridge: Cambridge University Press. 312 pp., 64,46€ [ISBN 978-1-1082-9695-3] [Reseña]
Moss, C.R. (2019). Divine Bodies. Resurrecting Perfection in the New Testament and Early Christianity
Authors: Martínez Maza Clelia 
Published: December 2020

MOSS, CANDIDA R. (2019). Divine Bodies. Resurrecting Perfection in the New Testament and Early Chistianity. New Haven – London: Yale University Press. 208 pp., 38,38€ [ISBN 978-0-3001-7976-7] [Reseña]
Pandangan Pandangan Amina Wadud Terhadap Perempuan Menjadi Imam Sholat Laki-Laki
Authors: Abubakar Syukri , Mutawali Muhammadmutawali 
Published: December 2020

This paper is motivated by the writer's anxiety about the thought of Amina Wadud, which is quite controversial about the permissibility of women to be male prayer priests, because for more than 14 centuries, there has never been a single scholar, both male and female ulama, who dared to think so, even Amina Wadud immediately practiced her opinion by leading the prayers of men and women so that many sneers and blasphemies were directed at her. Therefore, the question arises, why does Amina Wadud think so and what is the background? The results of this study show that in interpreting the Qur'an and the hadith, Amina Wadud used the Hermeneutic method which she called the monotheistic interpretation (holistic interpretation method) which she adopted from Fazlurrahman's thoughts. By implementing this monotheistic interpretation, according to him, reading the Koran related to women's rights is no longer gender biased, but can reveal fundamental principles in the Koran, such as the principle of justice and the principle of equality, so based on the hadith of Umm Waraqah , he allows women to become Imam of Prayer.
Tulisan ini dilatarbelakangi oleh kegelisahan penulis mengenai pemikiran Amina Wadud yang cukup kontroversial tentang bolehnya perempuan menjadi imam sholat laki-laki, karena selama lebih kurang 14 abad, tidak pernah ada seorang pun ulama baik ulama laki-laki maupun ulama perempuan yang berani berpendapat demikian, bahkan Amina Wadud langsung mempraktekkan pendapatnya dengan mengimami sholat laki-laki dan perempuan sehingga banyak cibiran dan hujatan yang ditujukan kepadanya. Oleh karena itu, maka muncul pertanyaan, mengapa Amina Wadud berpendapat demikian dan apa yang melatarbelakanginya?. Hasil kajian ini menunjukkan bahwa dalam menafsirkan al-Qur’an dan hadist, Amina Wadud menggunakan metode Hermeneutik yang ia disebut dengan tafsir tauhid (metode penafsiran holistik) yang dia adopsi dari pemikiran Fazlurrahman. Dengan mengimplementasikan tafsir tauhid ini, menurutnya, pembacaan al-Qur’an terkait hak-hak perempuan tidak lagi bias gender, tapi dapat mengungkap prinsip-prinsip fundamental dalam al-Qur’an, seperti prinsip keadilan dan prinsip kesetaraan, sehingga berdasarkan hadist Ummu Waraqah, ia memperbolehkan perempuan menjadi Imam Sholat.
MENINGKATKAN KETERAMPILAN MEMBACA PERMULAAN DENGAN MENGGUNAKAN MEDIA GAMBAR PADA SISWA KELAS I SDN 10 MONTONG BETOK KECAMATAN MONTONG GADING
Authors: Bahrah Baiq 
Published: December 2020

Tujuan penelitian ini adalah untuk meningkatkan keterampilan membaca permulaan dengan penggunaan media gambar pada siswa kelas I SD Negeri 10 Montong Betok semester II Mata Pelajaran Bahasa Indonesia TP 2018/2019. Penelitian ini merupakan penelitian tindakan kelas yang dilaksanakan dalam dua siklus. Masing-masing siklus mencakup 4 tahapan yaitu perencanaan tindakan, pelaksanaan tindakan, evaluasi, dan refleksi. Subyek penelitian ini adalah siswa kelas 1 SDN 10 Montong Betok Kecamatan Montong Gading. Objek penelitian ini adalah peningkatan keterampilan membaca permulaan siswa dengan penggunaan lafal, intonasi, kelancaran, dan ketepatan membaca pada siswa kelas 1 SD Negeri 10 Montong Betok, Kecamatan Mt. Gading, Kabupaten Lombok Timur. Hasil yang diperoleh pada siklus I yaitu rerata keterampilan membaca siswa sebesar 70,96 dengan presentase kelulusan sebesar 64,28 % dan presentase ketidaklulusan sebesar 35,72 %. Hasil pada siklus II menunjukkan rerata keterampilan membaca siswa adalah 73,96 dengan presenase kelulusan sebesar 85,71 % dan presentase ketidaklulusan sebesar 14,29 %. Berdasarkan hasil penelitian siklus I dan dan siklus II bahwa terdapat peningkatan persenatase keterampilan membaca siswa sebesar 21,28 % melalui pembeajaran dengan menggunakan media gambar.
The Implementation of Online Project-Based Learning Model With A Combination of Collaborative Learning to Improve The Learning Result of Digital Photo Composition
Authors: Susanti Anita Dian , Basori Basori , Efendi Agus 
Published: December 2020

<p>The purpose of this research was to improve the learning results of Digital Photo Composition through the implementation of Online Project Based Learning model with a combination of Collaborative Learning on Multimedia students of SMK Negeri Takeran. This research was Classroom Action Research (CAR) with the cycle model of collaboration between researcher dan teacher. This survey was conducted in two cycles with each cycle consisting of planning, acting, observing, and reflecting. These subjects were students of Multimedia eleventh grade of SMK Negeri Takeran, which consisted of 22 students. The data collection technique was a test, observation, interview, and documentation. The data validity tests of the research were a triangulation of source and triangulation of method. The data analyzed technique was quantitative-descriptive analysis technique. Based on the result of this survey, it could conclude that implementation of Online Project Based Learning model with a combination of Collaborative Learning can improve learning result at Multimedia eleventh grade of SMK Negeri Takeran. It proved by the increase of average scores in the cognitive test for each cycle. The average value of pra-cycle was 69,82 with the completeness of 22,73% or 5 of 22 students. While on the cycle I was 77,5 with the completeness of 63,64% or 14 of 22 students. The average score of cycle II was 83,95 with the integrity of 81,82% or 18 of 22 students.</p>
Experience in conducting tests on a torsiometer to determine the pitch of the metal cord
Authors: Akunets N. A. 
Published: December 2020

Hardware production is in continuous improvement: the requirements imposed by consumers stimulate the introduction of new technological solutions and equipment. For metal products produced by hardware shops (metal cord, wire for RVD, side bronzed wire), mechanical properties are important, which determine the strength, ductility and other characteristics of materials. Metal cord has a number of physical and chemical characteristics: the diameter of the metal cord, lay pitch, linear density, deviation from straightness, residual torsion, untwistability, characteristics of the brass coating-chemical composition – coating weight, brass thickness, adhesion, mechanical properties-breaking load, elongation at break.The article describes the procedure for measuring the size of the lay pitch on a torsiometer installed by Metro Com engineering S. p. A., Italy using an upgraded device with ten pulses (resolution of the turn counter = 0.1 rotation of the rotating clamp). Comparative tests of 2x0. 30NT metal cord samples taken from a single coil were performed using a device with a resolution of 0.25 turns and 0.1 turns of the rotating clamp of the installation to determine the pitch of the coil.
Creation of bladder assembloids by reconstituting tissue stem cell/tumour cell-derived organoids with multiple stromal components
Authors: Kim Eunjee , Choi Seoyoung , Shin Kunyoo 
Published: December 2020

Abstract
Current organoid models are limited by their inability to mimic mature organ architecture and associated tissue microenvironments1,2. Here, we create multi-layered normal bladder assembloids and tumour assembloids by reconstituting tissue stem cell/tumour cell-derived organoids with multiple stromal components to represent an organized tissue architecture and functionality of adult bladder, and to mimic in vivo pathophysiological features of patient-derived urothelial carcinoma, respectively. Our assembloid model will facilitate development of an innovative model system for studying tissue regeneration and tumourigenesis at molecular and cellular levels, and also provide a unique experimental tool for establishing novel personalized therapeutic options, such as new drug screening strategies that are customized for different stages and types of cancer in individual patients.
Lightweight Model For The Prediction of COVID-19 Through The Detection And Segmentation of Lesions in Chest CT Scans
Authors: Ter-Sarkisov Aram 
Published: December 2020

Abstract
We introduce a lightweight Mask R-CNN model that segments areas with the Ground Glass Opacity and Consolidation in chest CT scans. The model uses truncated ResNet18 and ResNet34 nets with a single layer of Feature Pyramid Network as a backbone net, thus substantially reducing the number of the parameters and the training time compared to similar solutions using deeper networks. Without any data balancing and manipulations, and using only a small fraction of the training data, COVID-CT-Mask-Net classification model with 6.12M total and 600K trainable parameters derived from Mask R-CNN, achieves 91.35% COVID-19 sensitivity, 91.63% Common Pneumonia sensitivity, 96.98% true negative rate and 93.95% overall accuracy on COVIDx-CT dataset (21191 images). We also present a thorough analysis of the regional features critical to the correct classification of the image. The full source code, models and pretrained weights are available on https://github.com/AlexTS1980/COVID-CT-Mask-Net.
Association Between Mode of Delivery and Body Mass Index at 4-5 Years in White British and Pakistani Children: the Born in Bradford Birth Cohort
Authors: Ralphs Eleanor , Pembrey Lucy , West Jane , Santorelli Gillian 
Published: December 2020

Abstract
Background Globally, it is becoming more common for pregnant women to deliver by caesarean section (CS). In 2012, 21% of births in the UK were CS, surpassing the recommended prevalence of 15%. Concerns have been raised regarding potential unknown consequences of this mode of delivery.Childhood adiposity is also an increasing concern. Previous research provides inconsistent conclusions on the association between CS and childhood adiposity. More studies are needed to investigate the consequences of CS in different populations and ethnicities. Therefore, this study investigates the association between mode of delivery and BMI, in children of 4-5 years and if this differs between White British (WB) and Pakistani ethnicities, in Bradford UK.Methods Data were obtained from the Born in Bradford (BiB) cohort, which recruited pregnant women at the Bradford Royal Infirmary, between 2007-2010. For these analyses, a sub-sample (n=6410) of the BiB cohort (n=13858) was used. Linear regression models determined the association between mode of delivery (vaginal or CS) and BMI z-scores at 4-5 years. Children were categorised as underweight/healthy weight, overweight and obese, and logistic regression models determined the odds of adiposity. Effect modification by ethnicity was also explored.Results Multivariable analysis found no evidence for a difference in BMI z-score between children of CS and vaginal delivery (0.005 kg/m2, 95% CI= -0.062–0.072, p=0.88). Neither was there evidence of CS affecting the odds of being overweight (OR=1.05, 95% CI=0.86–1.28, p=0.65), or obese (OR=0.98, 95% CI=0.74–1.29, p=0.87). There was no evidence that ethnicity was an effect modifier of these associations (p=0.97). Conclusion Having CS, compared to a vaginal delivery, was not associated with greater adiposity in children of 4-5 years in this population. Concerns over CS increasing adiposity in children are not supported by the findings reported here using the BiB study population, of both WB and Pakistani families.
Epidemiological Characteristics and Spatiotemporal Patterns of Scrub Typhus in Jiangxi Province, China, 2006-2018
Authors: Yang Shu , Liu Xiaobo , Gao Yuan , Chen Baizhou , Lu Liang , Zheng Weiqing , Fu Renlong , Yuan Chenying , Liu Qiyong , Li Guichang , Chen Haiying 
Published: December 2020

Abstract
With the increasing incidence of scrub typhus (ST) in Jiangxi, it is valuable for the control and management to explore the epidemiological characteristics and spatiotemporal patterns of ST. Fisher's exact tests, seasonal decomposition analysis, spatial autocorrelation analysis, and space-time scan statistical analyses were performed to detect the epidemiological features and spatiotemporal patterns of ST. From 2006 to 2018, a total of 5,508 ST cases were reported in Jiangxi, which increased rapidly. Of these, female cases, cases aged 40 years old and above and farmers accounted for 63.42%, 88.2%, and 92.2%, respectively. The majority of cases occurred each year between June and October, with a bi-peak seasonal pattern in summer and autumn. The spatiotemporal dynamics of ST varied over the study period with high-risk areas identified in the southern and eastern part of Jiangxi. Seven spatiotemporal clusters were detected using Kulldorff’s space-time scan statistic, and the primary cluster covered one county, Nanfeng county. The results of this study demonstrated that targeted intervention should be executed in high-risk counties of ST in Jiangxi to mitigate the growing threat of ST in the province.