bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trends in extreme temperature and rainfall indices in the semi-arid areas of Western Tigray, Ethiopia
Authors: Berhane Abadi , Hadgu Gebre , Worku Walelign , Abrha Berhanu 
Published: February 2020

Abstract
Background
Africa is the most vulnerable continent in the world; which recurrent droughts, extreme temperature and rainfall affects agriculture and food security. The aim of this study was to analyze the trends in extreme temperature and rainfall in major sesame producing areas in western Tigray using RClimDex software. We selected eight temperature and nine rainfall indices from 27 extreme temperature and rainfall indices, which are recommended by joint CCL/CLIVAR/JCOMM Expert Team on Climate Change Detection and Indices (ETCCDI). A non-parametric Mann–Kendall test and Sen’s slope estimates were used to test the statistical significance and trend of each of the extreme temperature and rainfall indices, respectively.

Results
Number of heavy rainy days, number of very heavy rainy days, very wet days, extremely wet days, and maximum 5 days precipitation showed a negative trend, with significant (p < 0.05) decrease throughout the study area. Monthly maximum value of maximum and minimum value of maximum temperature, monthly maximum and minimum value of minimum temperature, hot days and hot nights revealed positive trend throughout the study areas. Total rainfall was decreasing significantly (p < 0.05) by 13.34 mm, 13.8 mm, 14.65 mm, 10.9 mm and 8.4 mm/year at Humera and Dansha, Adiremets, Maygaba, Maytsebri and Sheraro, and Adigoshu, respectively. Spatial analysis on extreme temperature also indicated there was relatively lower variability on minimum temperature in Humera, Dansha, Adiremets, and Adigoshu. On average, the western part of Tigray experienced a reduction in total rainfall ranging 8.45 to 14.7 mm/year; and increase in average maximum temperature of 0.04 to 0.051 °C/year since 1983 to 2016. The results also revealed an increase in warm nights and warm days ranging from 0.31 to 0.62 days, and 0.38 to 0.71 days/year, respectively.

Conclusions
Increase in temperature and decrease in amount of rainfall may have a negative impact on crop transpiration, photosynthetic rate and soil water balance; exacerbating distribution and infestation of malaria and leishmaniasis. The results in this study could have an important role in identifying possible present and future production strategies on sesame, cotton, and sorghum crops, which are essential cash crops produced by farmers and investors.
The impact of production shocks on maize markets in Ethiopia: implications for regional trade and food security
Authors: Yami Mesay , Meyer Ferdi , Hassan Rashid 
Published: February 2020

AbstractIn this article, we demonstrated the dynamic impact of a bumper harvest and drought shocks on the maize market and on the trade regime in Ethiopia. Regional market integration of Ethiopia’s white maize market with the South Sudan and Kenyan maize markets was also examined using cointegration analysis. Despite the renewed conflict in South Sudan, Addis Ababa maize market is cointegrated with Juba’s maize market. The simulation analysis indicated that a 20% increase in maize yield could reduce the maize price by 81%. This implies a decrease in the maize price level of 70% (110 USD/t) below the export parity price. This makes maize exports profitable and shifts the trade regime from autarky to an export parity regime. On the other hand, the effect of a drought could increase maize prices by 61% in the short run (within the year). At the current market price, the domestic maize price is wandering between the border prices and it is unprofitable to export maize. Therefore, lifting the export ban, even during normal harvest seasons, would not do any harm to the domestic maize price.
Estimation of the source process and forward simulation of long-period ground motion of the 2018 Hokkaido Eastern Iburi, Japan, earthquake
Authors: Kubo Hisahiko , Iwaki Asako , Suzuki Wataru , Aoi Shin , Sekiguchi Haruko 
Published: February 2020

AbstractIn this study, we investigate the source rupture process of the 2018 Hokkaido Eastern Iburi earthquake in Japan (MJMA6.7) and how the ground motion can be reproduced using available source and velocity models. First, we conduct a multiple-time-window kinematic waveform inversion using strong motion waveforms, which indicates that a large slip area located at a depth of 25–30 km in the up-dip direction from the hypocenter was caused by a rupture propagating upward 6–12 s after its initiation. Moreover, the high-seismicity area of aftershocks did not overlap with the large-slip area. Subsequently, using the obtained source model and a three-dimensional velocity structure model, we conduct a forward long-period (< 0.5 Hz) ground-motion simulation. The simulation was able to reproduce the overall ground-motion characteristics in the sedimentary layers of the Ishikari Lowland.
Studies on the cold tolerance of ratoon ‘Chaling’ common wild rice
Authors: Xu Mengliang , Li Xiangzhen , Mo Xiang , Tu Siyu , Cui Yanchun , Yang Daichang 
Published: February 2020

Abstract
Background
Rice is the staple food of many people around the world. However, most rice varieties, especially widely grown indica varieties and hybrids, are sensitive to cold stress. In order to provide a basis for the utilization of a common wild rice (CWR, Oryza rufipogon Griff.) named ‘Chaling’ CWR in cold-tolerant rice breeding and deepen the understanding of rice cold tolerance, the cold tolerance of ratoon ‘Chaling’ CWR was studied under the stress of the natural low temperature in winter in Changsha, Hunan province, China, especially under the stress of abnormal natural low temperature in Changsha in 2008, taking other ratoon CWR accessions and ratoon cultivated rice phenotypes as control.

Results
The results showed that ratoon ‘Chaling’ CWR can safely overwinter under the natural conditions in Changsha (28° 22′ N), Hunan province, China, which is a further and colder northern place than its habitat, even if it suffers a long-term low temperature stress with ice and snow. In 2008, an extremely cold winter appeared in Changsha, i.e., the average daily mean temperature of 22 consecutive days from January 13 to February 3 was − 1.0 °C, and the extreme low temperature was − 4.7 °C. After subjected to this long-term cold stress, the overwinter survival rate of ratoon ‘Chaling’ CWR was 100%, equals to that of ratoon ‘Dongxiang’ CWR which is northernmost distribution in the word among wild rice populations, higher than those of ratoon ‘Fusui’ CWR, ratoon ‘Jiangyong’ CWR, and ratoon ‘Liujiang’ CWR (63.55–83.5%) as well as those of ratoon ‘Hainan’ CWR, ratoon ‘Hepu’ CWR, and all the ratoon cultivated rice phenotypes including 3 japonica ones, 3 javanica ones, and 5 indica ones (0.0%).

Conclusions
The results indicate that ratoon ‘Chaling’ CWR possesses strong cold tolerance and certain freezing tolerance.
Intratumoral pseudoaneurysm within a liver metastasis of gastric cancer: a case report
Authors: Ohara Hiroki , Ishibashi Yuji , Yoshimura Shuntaro , Yamazaki Ryoto , Hatao Fumihiko , Koshiishi Takeshi , Morita Yasuhiro , Imamura Kazuhiro 
Published: February 2020

Abstract
Background
Intrahepatic artery pseudoaneurysms are mostly iatrogenic and result from hepatobiliary interventions. The incidence of intrahepatic artery pseudoaneurysms within liver tumors without prior intervention is extremely rare. We presented herein the first report of a case of an intratumoral pseudoaneurysm within a liver metastasis of gastric cancer without any prior intervention during chemotherapy.

Case presentation
A 59-year-old male patient underwent a distal gastrectomy and D2 lymph node dissection for gastric cancer. He was treated in the emergency room for right abdominal pain following the 4th cycle of nivolumab administration as second-line chemotherapy after adjuvant chemotherapy with S-1 and first-line chemotherapy for a liver metastasis of gastric cancer with ramucirumab plus paclitaxel. CT showed a 72-mm metastatic liver tumor containing a 9-mm pseudoaneurysm and fluid collection around the hepatic edge. Intrahepatic artery pseudoaneurysm within the metastatic liver tumor was diagnosed, with the surrounding fluid indicating potential, active bleeding. An emergency angiography confirmed the presence of a pseudoaneurysm in the intrahepatic artery, which was embolized using microcoils. The contributory causes of the intratumoral pseudoaneurysm were assumed to be the following: (1) tumor necrosis leading to encasement, erosion of the vessel wall, and subsequent arterial wall weakening; and (2) inhibition of vascular endothelial growth by ramucirumab resulting in a vessel wall breach and pseudoaneurysm formation.

Conclusion
It is necessary to recognize that pseudoaneurysms can arise within a metastatic liver tumor during chemotherapy.
Implementation of a multidisciplinary discharge videoconference for children with medical complexity: a pilot study
Authors: Ravid Noga L. , Zamora Kayla , Rehm Roberta , Okumura Megumi , Takayama John , Kaiser Sunitha 
Published: February 2020

Abstract
Background
The hospital to home transition for children with medical complexity (CMC) poses many challenges, including suboptimal communication between the hospital and medical home. Our objective was to evaluate the implementation of a discharge videoconference incorporating the patient, caregiver, primary care provider (PCP), hospitalist physician, and case manager.

Methods
We evaluated implementation of this pilot intervention at a freestanding tertiary care children’s hospital using mixed methods. A discharge videoconference was conducted for hospitalized children (< 18 years old) meeting complex chronic disease (C-CD) criteria. We collected field notes and conducted surveys and semi-structured interviews. Outcomes included adoption, cost, acceptability, feasibility, and appropriateness. Adoption, cost, and acceptability were analyzed using descriptive statistics. Acceptability, feasibility, and appropriateness were summarized using thematic content analysis.

Results
Adoption: A total of 4 CMC (9% of the 44 eligible children) had discharge videoconferences conducted. Cost (in provider time): On average, videoconferences took 5 min to schedule and lasted 21.5 min. Acceptability: All hospitalists involved (n = 4) were very likely to participate again. Interviews with caregivers (n = 4) and PCPs (n = 5) demonstrated that for those participating, videoconferences were acceptable and appropriate due to benefits including development of a shared understanding, remote physical assessment by the PCP, transparency, and humanization of the care handoff, and increased PCP comfort with care of CMC. Feasibility: Barriers included internet connection quality and scheduling constraints.

Conclusions
This novel, visual approach to discharge communication for CMC had low adoption, possibly related to recruitment strategy. The videoconference posed low time burdens, and participating physicians and caregivers found them acceptable due to a variety of benefits. We identified several feasibility barriers that could be targeted in future implementation efforts.
Imaging properties of 3D printed breast phantoms for lesion localization and Core needle biopsy training
Authors: Ali Arafat , Wahab Rifat , Huynh Jimmy , Wake Nicole , Mahoney Mary 
Published: February 2020

Abstract
Background
Breast cancer is the most commonly diagnosed malignancy in females and frequently requires core needle biopsy (CNB) to guide management. Adequate training resources for CNB suffer tremendous limitations in reusability, accurate simulation of breast tissue, and cost. The relatively recent advent of 3D printing offers an alternative for the development of breast phantoms for training purposes. However, the feasibility of this technology for the purpose of ultrasound (US) guided breast intervention has not been thoroughly studied.

Methods
We designed three breast phantom models that were printed in multiple resins available through Stratasys, including VeroClear, TangoPlus and Tissue Matrix. We also constructed several traditional breast phantoms using chicken breast and Knox gelatin for comparison. These phantoms were compared side-by-side for ultrasound penetrance, simulation of breast tissue integrity, anatomic accuracy, reusability, and cost.

Results
3D printed breast phantoms were more anatomically accurate models than traditional breast phantoms. The chicken breast phantom provided acceptable US beam penetration and material hardness for simulation of human breast tissue integrity. Sonographic image quality of the chicken breast phantom was the most accurate overall. The gelatin-based phantom also had acceptable US beam penetration and image quality; however, this material was too soft and poorly simulated breast tissue integrity. 3D printed phantoms were not visible under US.

Conclusions
There is a large unmet need for a printable material that is truly compatible with multimodality imaging for breast and other soft tissue intervention. Further research is warranted to create a realistic, reusable and affordable material to 3D print phantoms for US-guided intervention training.
Terlipressin infusion for prevention of vasoplegic syndrome in patients treated with angiotensin II receptor antagonist undergoing coronary artery bypass graft surgery: a randomized controlled study
Authors: Saleh Mohamed , Kodeira Sherine Kamal Zaki , Aboulseoud Abdelkhalek Abdelmoneim 
Published: February 2020

Abstract
Background and objectives
Preoperative use of renin angiotensin system antagonists has been considered an independent risk factor for development of vasoplegic syndrome. The aim of this study was to demonstrate efficacy of prophylactic terlipressin infusion for prevention of vasoplegic syndrome in patients treated with angiotensin receptor blocker undergoing coronary artery bypass graft surgery.

Patients and methods
One hundred patients on angiotensin II receptor antagonist [losartan] scheduled for coronary artery bypass surgery were enrolled into this prospective randomized controlled study. Anesthetic technique, surgical technique, and cardiopulmonary bypass management were standardized for all patients. With the start of rewarming, patients were randomized to receive either terlipressin infusion 1.3 μg.kg−1.hour−1, or normal saline infusion. Incidence of vasoplegic syndrome score was used as primary outcome. Hemodynamic parameters, inotropic score, and vasopressor dependency index were used as secondary outcome.

Results
Incidence of vasoplegic syndrome was significantly lower in terlipressin group compared to placebo group. Norepinephrine was required in 2 patients of terlipressin versus 15 patients of placebo group. Mean arterial blood pressure was significantly higher in terlipressin group compared to placebo group (81.7 ± 18.5 versus 69.3 ± 20.2 at 60 min after weaning from CBP). Cardiac index was significantly lower in terlipressin group compared to placebo group (2.52 ± 1.48 versus 3.2 ± 1.55). Systemic vascular resistance was significantly higher in terlipressin group compared to placebo group (2438.09 ± 735.13 versus 1575.05 ± 753.54). Inotropic score and vasopressor dependency index were significantly lower in terlipressin group compared to placebo group.

Conclusion
Prophylactic terlipressin infusion could prevent development of vasoplegic syndrome in patients treated with angiotensin II receptor antagonist undergoing coronary artery bypass graft surgery.

Trial registration
PACTR, PACTR201804003249274, Registered 25/03/2018—retrospectively registered, https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=3249.
Depression and Suicidal Ideation Among Patients With Cancer in the United States: A Population-Based Study
Authors: Abdel-Rahman Omar 
Published: February 2020

PURPOSE: To evaluate the association between cancer diagnosis and depression and suicidal ideation in a population-based cohort in the United States. METHODS: This was a cross-sectional study based on the National Health and Nutrition Examination Survey (NHANES) conducted for the years 2005 to 2016. Depression was assessed using a validated tool (Patient Health Questionnaire-9, and suicidal ideation was assessed by item number 9 of this tool. Propensity score matching was conducted to match survey respondents with cancer versus those without cancer. Multivariable logistic regression analysis was then conducted to evaluate factors associated with higher probability of depression and suicide among the whole postpropensity cohort. RESULTS: A total of 32,178 survey respondents were eligible and included in the study. These included 3,043 respondents with cancer and 29,675 respondents without cancer. Within the postpropensity cohort, a cancer diagnosis was not associated with a higher probability of depressive disorders (odds ratio, 0.937; 95% CI, 0.819 to 1.073), whereas it was associated with a higher probability of suicidal ideation (for respondents without cancer v those with cancer: odds ratio, 0.695; 95% CI, 0.517 to 0.935). CONCLUSION: Cancer diagnosis is associated with a higher probability of suicidal ideation. Screening for suicidal ideation should be part of the assessment of patients with cancer.
Features of Multiple Endocrine Neoplasia Type 1 and 2A in a Patient with Both RET and MEN1 Germline Mutations
Authors: Brown Spandana J , Riconda Daniel L , Zheng Feibi , Jackson Gilchrist L , Suo Liye , Robbins Richard J 
Published: February 2020

Abstract
The coexistence of multiple endocrine neoplasia type 1 (MEN1) and type 2A (MEN2A) is a rare occurrence and has been reported only twice in the literature. We present a patient with primary hyperparathyroidism and medullary thyroid cancer with strong family history of both MEN1- and MEN2A-associated conditions. Genetic testing showed the patient had a novel MEN1 loss-of-function mutation, c0.525_526insTT (p.Ala176Leufs*10), and an uncommon Cys630Tyr RET mutation. This case highlights the importance of obtaining a detailed family history when heritable endocrine disorders are suspected.
Risk factors, presentation and outcome of meningomyelocele repair
Authors: Rehman Lal , Sheikh Munwar , Afzal Ali , Rizvi Raza 
Published: February 2020

Objective: To determine the risk factors, presentation and outcome of meningomyelocele repair
Methods: We reviewed 150 cases operated for meningomyelocele (MMC) at Jinnah Postgraduate Medical Centre Karachi between May 2015 and May 2018. Data of infants operated for MMC repair was extracted including socioeconomic status, maternal folate intake during pregnancy, head circumference, location and width of the defect, accompanying bladder and limb anomalies and treatments administered. Patients were followed up for a mean period of six months.
Results: A total of 150 children were evaluated, out of which there were 83(55.3%) males and 67(44.7%) females. All belonged to low socio economic group and prenatal maternal folate intake as risk factor was positive in 103(68.7%) cases. Mean head circumference was 37.4 cm (range, 30.7 to 50 cm). Based on their location, 83(55%) of the defects were lumbosacral, 38(25.4%) were lumbar, 16(10.7%) were thoraco lumbar, 10(6.7%) were thoracic and three (2%) were cervical. Mean size of the meningomyelocele sac was 4.3 cm×5.6 cm (range, 1cm×2cm to 11cm×8.4cm) and 21(14%) of the babies had a skin defect requiring flap. According to accompanying anomalies, 98(65.3%) of the babies had hydrocephalus, 13(9%) had club foot, four (2.7%) had diastematomyelia and three (2%) had tethered cord. Eighty seven (58%) patients had neurological deficit pre operatively and eight (5.4%) patients with normal power deteriorated after surgery out of which five (3.3%) developed paraplegia and three (2%) developed paraparesis. CSF leak was the major complication encountered in 16(11%) followed by meningitis in seven (5%), while the overall mortality was four (2.6%).
Conclusion: The practice of periconceptional folic acid supplementation is essential to reduce the prevalence of neural tube defects (NTDs) in the developing world. Improved maternal nutrition with access to quality antenatal care is vital to decrease the prevalence and health burden.
doi: https://doi.org/10.12669/pjms.36.3.1237
How to cite this:Rehman L, Shiekh M, Afzal A, Rizvi R. Risk factors, presentation and outcome of meningomyelocele repair. Pak J Med Sci. 2020;36(3):422-425. doi: https://doi.org/10.12669/pjms.36.3.1237
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Mitteformaalõppe tähenduse konstrueerimine poliitikadokumentides
Authors: Karu Katrin , Jõgi Larissa , Rannala Ilona-Evelyn , Roosalu Triin , Teder Lianne , Põlda Halliki 
Published: February 2020

Artikkel tugineb uuringule, mille fookuses on mitteformaalõppe tähendus ja diskursuse muutus Eesti arengut suunavates poliitikadokumentides. Selline rõhuasetus on tingitud asjaolust, et mitteformaalõppe tähendus on sotsiaalselt konstrueeritud, paradigma- ja kontekstispetsiifiline ning sõltub ideoloogiast, hariduspoliitilisest korraldusest, traditsioonidest ja väljakujunenud tavadest. Uurimuses kombineeritakse kriitilist diskursuseanalüüsi poliitikaradade meetodiga ning esitatakse mitteformaalõppe diskursuse ajalise ja valdkondliku kasutuse analüüs. Analüüsi tulemusena eristus kuus valdkondlikku poliitikadokumentide rada, kümme mitteformaalõppe aladiskursust ja viis diskursust: keskkonna-, eristumis-, kaasamis-, süsteemi- ja tunnustamisdiskursus. Mitteformaalõppe tunnustamise diskursus eristus diskursusteülesena ning selles ilmnevad võimalikud edasised muutused mitteformaalõppe sisu ja vormi sotsiaalsel konstrueerimisel poliitikadokumentides.
Summary
Promising Areas for Advanced Training of Subject Teachers in the Training System for Participants of the All-Russian Olympiad for Schoolchildren
Authors: Tsvetkova Marina , Abaturova Valentina , Kiryukhin V. 
Published: February 2020

The article describes the problem of the current state of the all-Russian Olympiad of schoolchildren: formed accessible creative environment for children with maximum coverage of students in the school stage of the all-Russian Olympiad in all subjects in all schools of the country, on the one hand, and the lack of systematic training with coverage of all subject teachers in all schools of regions of Russia, on the other hand.
The structure and approximate content of the standard training program for subject teachers as school mentors on the specifics of preparing students to participate in the all-Russian Olympiad are presented.
Design of a narrowband retroreflector based on guided-mode resonance
Authors: Inoue Junichi , Kusuura Toshiki , Akamatsu Keita , Ura Shogo 
Published: February 2020

A narrowband retroreflector consisting of a grating coupler and a waveguide cavity integrated on a highly reflective substrate is proposed. A theoretical model based on coupled-mode theories is discussed to provide analytical expression of the reflection and transmission coefficients under oblique incidence. The retroreflector was designed with a 20-µm aperture for 1540-nm-wavelength operation and 8-deg-angle incidence. Finite-difference time-domain simulation showed a retroreflection spectrum with a bandwidth of 2 nm and a maximum retroreflectance of 85% and a minimum specular reflectance of 5%.