bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘It's Not Gossip, It's True’: Denunciation and Social Control during the Guatemalan Armed Conflict (1970–85)
Authors: Janssens Joren F. 
Published: November 2020

AbstractPractices of denunciation are at once ubiquitous and marginalised in literature on the Guatemalan armed conflict. Meanwhile, ordinary Guatemalans who spontaneously denounced neighbours, former friends and fellow villagers have largely escaped scrutiny in scholarly work on low-level perpetrators. Departing from untapped confidential documents in the Historical Archive of the National Police, this article provides the first archival study of denunciatory behaviour during the Guatemalan Civil War, specifically at the height of the conflict (1970–85). This contribution reveals both the strategic considerations that spurred state intelligence apparatuses to elicit civilian information as well as the broad range of personal, opportunistic and strategic motives that drove civilians to denounce. The case study questions scholarly consensus on the spontaneous and voluntary character of denunciation by arguing that besides providing novel pathways for opportunistic action, denunciations also opened up new strategies for survival in the face of a civil war that structured available choices.
Work at age 62: expectations and realisations among recent cohorts of Americans
Authors: Abrams Leah R. , Clarke Philippa J. , Mehta Neil K. 
Published: November 2020

AbstractMuch remains unknown about how the 2008 Great Recession, coupled with the ageing baby-boomer cohort, have shaped retirement expectations and realised retirement timing across diverse groups of older Americans. Using the Health and Retirement Study (1992–2016), we compared expectations about full-time work at age 62 (reported at ages 51–61) with realised labour force status at age 62. Of the 12,049 respondents, 34 per cent reported no chance of working full time at 62 (zero probability) and 21 per cent reported it was very likely (90–100 probability). Among those reporting no chance of working, there was a 0.111 probability of unmet expectations; among those with high expectations of working, there was a 0.430 probability of unmet expectations. Black and Hispanic Americans were more likely than white Americans to have unmet expectations of both types. Educational attainment was associated with higher probability of unexpectedly working and lower probability of unexpectedly not working. Baby-boomers experienced fewer unmet expectations than prior cohorts but more uncertainty about work status at 62. Our findings highlight the unpredictability of retirement timing for significant segments of the US population and the role of the Great Recession in contributing to uncertainty. Given the individual and societal benefits of long work lives, special attention should be paid to the high rates of unexpectedly not working at age 62.
The role of simulation in imagery rescripting for post-traumatic stress disorder: a single case series
Authors: Looney Kathy , El-Leithy Sharif , Brown Gary 
Published: November 2020

AbstractBackground:Imagery rescripting (ImRs) is an experiential therapy technique used to change the content and meaning of intrusive imagery in post-traumatic stress disorder (PTSD) by imagining alternative endings to traumatic events. There is growing evidence that ImRs is an effective treatment for PTSD; however, little is known about how it brings about change.Aims:This study aimed to explore the role of mental simulation as a candidate mechanism of action in ImRs, and, specifically, whether well-simulated imagery rescripts are associated with greater change in symptom severity during ImRs.Method:Using a single-case experimental design, seven participants receiving cognitive therapy for PTSD were assessed before, during and after sessions of imagery rescripting for one intrusive image. Participants completed continuous symptom severity measures. Sessions were recorded, then coded for goodness of simulation (GOS) as well as additional factors (e.g. rescript believability, vividness).Results:Participants were divided into high- and low-responders and coding was compared across groups. Correlational analyses were supported by descriptive analysis of individual sessions. High-responders’ rescripts tended to be rated as well-simulated compared with those of low-responders. Specific factors (e.g. intensity of thoughts/emotions related to original and new imagery elements, level of cognitive and emotional shift and belief in the resultant rescript) were also associated with reductions in symptom severity.Conclusions:There was tentative evidence that well-simulated rescripted images tended to be associated with greater reductions in symptom severity of the target image. Clinical implications and avenues for further research are discussed.
Multiple burdens of malnutrition and relative remoteness in rural Ecuadorian communities
Authors: Lee Gwenyth O , Gutierrez Cynthia , Castro Morillo Nancy , Cevallos William , Jones Andrew D , Eisenberg Joseph NS 
Published: November 2020

AbstractObjective:Social and economic changes associated with new roads can bring about rapid nutritional transitions. To study this process, we: (1) describe trends in adult overweight and obesity (OW/OB) among rural Afro-Ecuadorians over time and across a gradient of community remoteness from the nearest commercial centre; (2) examine the relationship between male and female adult OW/OB and factors associated with market integration such as changing livelihoods and (3) examine the co-occurrence of adult OW/OB and under-five stunting and anaemia.Design:Adult anthropometry was collected through serial case–control studies repeated over a decade across twenty-eight communities. At the same time, anthropometry and Hb were measured for all children under 5 years of age in every community.Setting:Northern coastal Ecuador.Participants:Adults (n 1665) and children under 5 years of age (n 2618).Results:From 2003 and 2013, OW/OB increased from 25·1 % to 44·8 % among men and 59·9 % to 70·2 % among women. The inverse relationship between remoteness and OW/OB in men was attenuated when adjusting for urban employment, suggesting that livelihoods mediated the remoteness–OW/OB relationship. No such relationship was observed among women. Communities with a higher prevalence of male OW/OB also had a greater prevalence of stunting, but not anaemia, in children under 5 years of age.Conclusions:The association between male OW/OB and child stunting at the community level, but not the household level, suggests that changing food environments, rather than household- or individual-level factors, drove these trends. A closer examination of changing socio-economic structures and food environments in communities undergoing rapid development could help mitigate future public health burdens.
IMPLEMENTATION OF HIGH-ORDER, DISCONTINUOUS GALERKIN TIME STEPPING FOR FRACTIONAL DIFFUSION PROBLEMS
Authors: MCLEAN WILLIAM 
Published: November 2020

AbstractThe discontinuous Galerkin (DG) method provides a robust and flexible technique for the time integration of fractional diffusion problems. However, a practical implementation uses coefficients defined by integrals that are not easily evaluated. We describe specialized quadrature techniques that efficiently maintain the overall accuracy of the DG method. In addition, we observe in numerical experiments that known superconvergence properties of DG time stepping for classical diffusion problems carry over in a modified form to the fractional-order setting.
ASYMPTOTIC BEHAVIOUR OF THE STOCHASTIC MAKI–THOMPSON MODEL WITH A FORGETTING MECHANISM ON OPEN POPULATIONS
Authors: LI HAIJIAO , YANG KUAN 
Published: November 2020

AbstractRumours have become part of our daily lives, and their spread has a negative impact on a variety of human affairs. Therefore, how to control the spread of rumours is an important topic. In this paper, we extend the classic Maki–Thompson model from a deterministic framework to a stochastic framework with a forgetting mechanism, because real-world person-to-person communications are inevitably affected by random factors. By constructing suitable stochastic Lyapunov functions, we show that the asymptotic behaviour of the stochastic rumour model is governed by the basic reproductive number. If this number is less than one, then the solution of the stochastic rumour model oscillates around the rumour-free equilibrium under extra mild conditions, indicating the extinction of the rumour with a probability of one. Otherwise, the solution always fluctuates around the endemic equilibrium under certain parametric restrictions, implying that the rumour will continually persist. In addition, we discuss a possible intervention strategy that stops the spread of rumours by strengthening the intensity of white noise, which is very different from the deterministic rumour model without white noise. Also, numerical simulations are conducted to support our analytical results.
Teaching end-of-life preparation to African Americans
Authors: Pruitt Delicia , Weber Kirsten , Ragina Neli 
Published: November 2020

AbstractObjectiveThis is a pilot study with a primary goal to develop an effective, targeted educational intervention that can serve as a teaching tool to educate African American (AA) population, especially the elderly, on options of end of life (EOL) prior to critical care.MethodWe first assessed the level of preparation for EOL in the AA community through a survey instrument. The survey was used to determine the deficits in knowledge in AA population in Mid-Michigan regarding EOL choices before and after the educational intervention. Paired-sample t-test was used to assess changes in understanding about EOL planning options. Regressions analysis was used to assess these changes while including several demographic covariates. P < 0.05 was considered statistically significant.ResultsOur pilot data indicated that the educational intervention could be used as an effective teaching tool in educating AA population on EOL choices.Significance of resultsAA patients are more likely to choose life-sustaining measures at the end of their lives compared to other ethnic groups despite terminal illness. This decision is partly based on lack of knowledge of the available options of care at the EOL. Due to multiple life-sustaining measures, the AA patients are not receiving the care to help them peacefully die. This study provides evidence that physicians will need to increase their educational efforts with the AA population to help them better understand EOL options. An educational tool like the one developed in this study may be helpful and lessen the time of education so that the physician can answer any questions at the end of the session and also empower individuals and communities to take an active role in creating a culture of wellness at the EOL and decreasing morbidity.
Pandemics and soft power: HIV/AIDS and Uganda on the global stage
Authors: Doyle Shane 
Published: November 2020

AbstractThe COVID-19 outbreak of 2020 threatened years of effort by the Chinese authorities to extend its influence around the world. This article seeks to enhance understanding of China’s defensive engagement with global health agencies, and more broadly of the relationship between pandemics and soft power, through an analysis of Uganda’s evolving response to HIV/AIDS. As with COVID-19, HIV/AIDS presented a fundamental threat not only to countries’ internal social stability and population health, but also to governmental legitimacy and nation-states’ international reputation. HIV, however, also provided Uganda with an opportunity to enhance its global standing, influence international policy, and achieve national reconstruction. This case study highlights the importance of viewing international affairs from the perspective of the Global South. It argues that the very weakness of Uganda, and the structural marginality of HIV/AIDS, provided the leverage which would in the end deliver radical shifts within global health.
How reminders of the 1918–19 pandemic helped Australia and New Zealand respond to COVID-19
Authors: Rice Geoffrey W. 
Published: November 2020

AbstractThis article will argue that the memory of the great ‘Spanish’ influenza pandemic of 1918–19 played a significant role in the preparedness and response of Australia and New Zealand to the COVID-19 pandemic, and may help to explain their success compared with Europe and North America. An obvious alternative explanation for the success of Asian states such as China, Singapore, Hong Kong, South Korea, Taiwan, and Japan would be their experience of the SARS outbreak in 2002 and the H7N9 influenza outbreak of 2013. However, this explanation does not apply to Australia or New Zealand. All of these states had pandemic plans, initially developed with encouragement from the World Health Organization after the SARS outbreak, but only Australia and New Zealand appear to have directly incorporated ‘lessons’ from 1918–19 into their pandemic plans.
Endemic risks: influenza pandemics, public health, and making self-reliant Indian citizens
Authors: Sivaramakrishnan Kavita 
Published: November 2020

AbstractThis article focuses on the politics of epidemics, health and development in the years between two pandemics of influenza in India, the so-called ‘Asian’ flu (1957) and the ‘Hong Kong’ flu (1968). I explore how public health and risk-focused cosmologies were constructed about urban life, and anchored in economic priorities about development planning, industrial productivity, and self-reliance in a modernizing Indian nation. How were pandemics ‘seen’ and identified among urban populations that were already suffering from endemic risks? Were they viewed as a continuum of local, natural hazards or through wider geopolitical insecurities? The influenza crises were characterized by incapacitation and absenteeism from work rather than high mortality rates in Indian cities, causing worries about industrial plans. The Indian state intervened minimally, and articulated ideas and rhetoric about individual responsibility and ‘cooperative citizenship’ that set the stage for later manifestations of neoliberalism.
Tolerance of rhizoma perennial peanut to glyphosate and triclopyr
Authors: Martin Logan J. , Sellers Brent A. , Devkota Pratap , Ferrell Jason A. , Leon Ramon G. , Vendramini João M.B. 
Published: November 2020

AbstractRhizoma perennial peanut (RPP) is well adapted to the Gulf Coast region of the United States, but its varietal tolerance to glyphosate and triclopyr is not well defined. The research was conducted to determine the effect of various rates of glyphosate and triclopyr on established RPP, and the response of common RPP varieties to these herbicides. The RPP sward was approximately 7 yr younger at Zolfo Springs than at the Ona location. RPP showed moderate tolerance to glyphosate and triclopyr application, and injury level did not differ with the age of RPP sward. However, biomass production was negatively influenced by the age of the RPP sward. Overall, injury from glyphosate applications did not exceed 40% at either site. The glyphosate rate for 20% biomass reduction was predicted to be 0.53 and 2.17 kg ae ha−1at Zolfo Springs and Ona, respectively. RPP injury from triclopyr was greater at the Zolfo Springs location than at Ona, and the triclopyr rate predicted to result in a 20% biomass reduction was 0.45 and 0.99 kg ae ha−1at the Zolfo Springs and Ona locations, respectively. There was a difference on RPP varieties response to glyphosate and triclopyr application. ‘Florigraze’ and ‘Ona 33’ were less tolerant to glyphosate compared to ‘UF-Tito’ and ‘Ecoturf’ at 30 d after treatment. Likewise, UF-Tito and Florigraze were less tolerant to triclopyr compared to Ona 33 and Ecoturf. Overall, Florigraze showed highest injury and at least 2-fold reduction on biomass compared to the other three varieties from glyphosate or triclopyr application. Results from this research indicate that glyphosate and triclopyr appear to be safe to apply to long-established RPP stands, but herbicide rate and RPP varieties should be considered if stands are <5 yr old.
Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting
Authors: Fu Xianglei , Shi Yanbin , Qi Tongtong , Qiu Shengnan , Huang Yi , Zhao Xiaogang , Sun Qifeng , Lin Guimei 
Published: November 2020

AbstractTherapeutic efficacy against cancer relies heavily on the ability of the therapeutic agents to reach their final targets. The optimal targets of most cancer therapeutic agents are usually biological macromolecules at the subcellular level, which play a key role in carcinogenesis. Therefore, to improve the therapeutic efficiency of drugs, researchers need to focus on delivering not only the therapeutic agents to the target tissues and cells but also the drugs to the relevant subcellular structures. In this review, we discuss the most recent construction strategies and release patterns of various cancer cell subcellular-targeting nanoformulations, aiming at providing guidance in the overall design of precise nanomedicine. Additionally, future challenges and potential perspectives are illustrated in the hope of enhancing anticancer efficacy and accelerating the translational progress of precise nanomedicine.
An evaluation of inbreeding measures using a whole-genome sequenced cattle pedigree
Authors: Alemu Setegn Worku , Kadri Naveen Kumar , Harland Chad , Faux Pierre , Charlier Carole , Caballero Armando , Druet Tom 
Published: November 2020

AbstractThe estimation of the inbreeding coefficient (F) is essential for the study of inbreeding depression (ID) or for the management of populations under conservation. Several methods have been proposed to estimate the realizedFusing genetic markers, but it remains unclear which one should be used. Here we used whole-genome sequence data for 245 individuals from a Holstein cattle pedigree to empirically evaluate which estimators best capture homozygosity at variants causing ID, such as rare deleterious alleles or loci presenting heterozygote advantage and segregating at intermediate frequency. Estimators relying on the correlation between uniting gametes (FUNI) or on the genomic relationships (FGRM) presented the highest correlations with these variants. However, homozygosity at rare alleles remained poorly captured. A second group of estimators relying on excess homozygosity (FHOM), homozygous-by-descent segments (FHBD), runs-of-homozygosity (FROH) or on the known genealogy (FPED) was better at capturing whole-genome homozygosity, reflecting the consequences of inbreeding on all variants, and for young alleles with low to moderate frequencies (0.10 < . < 0.25). The results indicate that FUNIand FGRMmight present a stronger association with ID. However, the situation might be different when recessive deleterious alleles reach higher frequencies, such as in populations with a small effective population size. For locus-specific inbreeding measures or at low marker density, the ranking of the methods can also change as FHBDmakes better use of the information from neighboring markers. Finally, we confirmed that genomic measures are in general superior to pedigree-based estimates. In particular, FPEDwas uncorrelated with locus-specific homozygosity.
Associations between hand function and electrophysiological measurements in hand osteoarthritis patients of different ages with or without carpal tunnel syndrome
Authors: Kim Young Hoon , Han Eun Young , Kim Jinseok , Seo Kyu-Bum , Jeon Young Tae , Im Sang Hee 
Published: November 2020

AbstractOsteoarthritis is a common degenerative disease that most frequently involves the hand. The objective was to compare clinical functional outcome measures including hand grip, pinch strength, and dexterity with various electrophysiological measures in patients of different ages with hand osteoarthritis with or without the presence of carpal tunnel syndrome (CTS). Patients with hand osteoarthritis (208 patients, 404 hands) who underwent hand-function tests and motor and sensory nerve conduction studies (NCS) between June 2015 and June 2016 were enrolled. The patients’ hands were assigned to carpal tunnel syndrome (CTS) (206 hands; mean age, 56.37 ± 10.52; male:female, 46:160) or control groups (198 hands; mean age, 57.88 ± 9.68; male:female, 55:143). The strength of hand grip and lateral pinch, the time required to complete the nine-hole pegboard test (9HPT), and motor and sensory nerve conduction parameters were measured and compared across age groups and between hands with or without CTS. The CTS group showed significantly lower hand grip and lateral pinch strength, and a longer time to complete the 9HPT in comparison with the control group. Female patients showed significantly lower hand grip and lateral pinch strength than male patients. However, there was no difference in the 9HPT completion time between genders. Multivariate regression analysis identified the amplitude of the median compound muscle action potential (CMAP), age, and male gender as independent predictors of grip strength (adjusted R2 = 0.679), and amplitude of median CMAP and male gender as independent predictors of KP strength (adjusted R2 = 0.603). Velocity of median CMAP, amplitude of median sensory nerve action potential, and age were identified as independent predictors of 9HPT time (adjusted R2 = 0.329). Nerve conduction measurements were significantly related to hand-function test results, and CTS induced significant deficits in strength and performance of the affected hand.
The potential use of Azolla pinnata as an alternative bio-insecticide
Authors: Ravi Rajiv , Rajendran Dinesh , Oh Wen-Da , Mat Rasat Mohd Sukhairi , Hamzah Zulhazman , Ishak Intan H. , Mohd Amin Mohamad Faiz 
Published: November 2020

AbstractFour different tests showed the effectiveness of Azolla pinnata plant extracts against Aedes aegypti and Aedes albopictus mosquitoes. In the adulticidal test, there was a significant increase in mortality as test concentration increases and A. pinnata extracts showed LC50 and LC95 values of 2572.45 and 6100.74 ppm, respectively, against Ae. aegypti and LC50 and LC95 values of 2329.34 and 5315.86 ppm, respectively, against Ae. albopictus. The ovicidal test showed 100% eggs mortality for both species tested for all the concentrations tested at 1500 ppm, 1000 ppm, 500 ppm, 250 ppm and 125 ppm. Both tested samples of Ae. aegypti and Ae. albopictus did not lay any eggs in the plastic cups filled with the A. pinnata extract but instead opted to lay eggs in the plastic cups filled with water during the oviposition deterrence test. Similarly, the non-choice test of Ae. aegypti mosquitoes laid eggs on the sucrose solution meant for the nutrient source of the mosquitoes instead of in the plastic cup that was designed to facilitate oviposition filled with the extract. This clearly indicates the presence of bioactive compounds which are responsible in adulticidal and ovicidal activity in Aedes mosquitoes and at the same time inducing repellence towards the mosquitoes. The LC–MS results showed mainly three important chemical compounds from A. pinnata extracts such as 1-(O-alpha-D-glucopyranosyl)-(1,3R,25R)-hexacosanetriol, Pyridate and Nicotinamide N-oxide. All these chemicals have been used for various applications such as both emulsion and non-emulsion type of cosmetics, against mosquito vector such as Culex pipens and Anopheles spp. Finally, the overall view of these chemical components from A. pinnata extracts has shown the potential for developing natural product against dengue vectors.