bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFEKTIVITAS PENERAPAN MOBILE APPLICATION “KAI ACCESS” OLEH KONSUMEN DI PT. KERETA API INDONESIA PERSERO DAERAH OPERASI 9 STASIUN JEMBER
Authors: Ayu Wangi Diantini Ni Putu , Sukidin Sukidin , Hartanto Wiwin 
Published: April 2020

Suatu perusahaan akan berupaya meningkatkan kualitas pelayanan untuk masyarakat. Salah satu perusahaan yang sudah mengembangkan beberapa inovasi yaitu PT. Kereta Api Indonesia (Persero) dengan menciptakan mobile application “KAI Access” yaitu aplikasi yang digunakan untuk membeli tiket secara online tanpa harus mengantri diloket stasiun. Oleh karena itu tujuan penelitian ini adalah untuk mengetahui efektivitas penerapan mobile application “KAI Access” di Stasiun Jember yang mengacu pada 6 (enam) aspek penilaian yaitu kualitas sistem, kualitas informasi, kualitas pelayanan, penggunaan, kepuasan pengguna, manfaat bersih. Penelitian ini merupakan penelitian deskriptif kuantitatif bertujuan untuk mengetahui nilai variabel mandiri yaitu efektivitas penerapan mobile application “KAI Access” tanpa membuat suatu perbandingan atau menghubungkan dengan variabel lain. Populasi dalam penelitian ini yaitu seluruh penumpang kereta api yang menggunakan mobile application “KAI Access” di Stasiun Jember yang terdiri dri 87 responden. Metode pengumpulan data yang digunakan adalah kuesioner, wawancara dan observasi.
Hasil penelitian menunjukkan bahwa efektivitas penerapan mobile application “KAI Access” oleh konsumen di PT. Kereta Api Indonesia (Persero) Daerah Operasi 9 Stasiun Jember dapat dikatakan sangat efektif. Hal ini dapat dilihat dari penilaian setiap sub variabel efektivitas yaitu kualitas sistem sebesar 85,28%, kualitas informasi sebesar 81%, kualitas pelayanan sebesar 80,85%, penggunaan sebesar 86%, kepuasan pengguna sebesar 82%, manfaat bersih sebesar 80,25%. Berdasarkan persentase nilai responden tersebut maka efektivitas penerapan mobile application “KAI Access” oleh konsumen di PT. Kereta Api Indonesia (Persero) Daerah Operasi 9 Stasiun Jember dinyatakan sangat efektif dimana termasuk dalam rentan nilai diatas 80%.
PENGARUH PENGALAMAN KERJA TERHADAP VOLUME PRODUKSI USAHA BATU BATA DI DESA SONOPATIK KABUPATEN NGANJUK
Authors: Sasongko Bhakti Dimas , Wahyuni Sri , Kartini Titin 
Published: April 2020

Penelitian ini brtujuan untuk mengetahui pengaruh yang signifikan pengalaman kerja terhadap volume produksi. Adapun penentuan lokasi penelitian menggunakan metode purposive area yaitu di Desa Sonopatik Kabupaten Nganjuk, sedangkan pengambilan sampel dilakukan dengan menggunakan metode Qouta Sampling dengan jumlah responden 80 pengrajin. Hasil penelitian menunjukkan bahwa pengalaman kerja memiliki pengaruh yang signifikan terhadap volume produksi usaha batu bata di Dea Sonopatik Kabupaten Nganjuk. Hasil Uji F menunjukkan Fhitung = 323,820 > Ftabel = 3,963 dengan tingkat signifikansi 0,000 < a = 0,05 dengan persamaan regresi sederhana Ŷ = 489.756 + 156.319X. Hasil perhitungan koefisien determinasi (R2) sebesar 0,806, hal ini menunjukkan bahwa besarnya persentase pengaruh Pengalaman kerja memiliki pengaruh yang signifikan terhadap volume produksi usaha batu bata di Dea Sonopatik Kabupaten Nganjuk sebesar 80,6%, sedangkan sisanya yakni 19,4% dipengaruhi oleh variabel bebas lain yang tidak diteliti dalam penelitian ini.
ANALISIS KONSEPTUAL TEORETIK PENDIDIKAN KEWIRAUSAHAAN SEBAGAI SOLUSI DAMPAK ERA INDUSTRI 4.0 DI INDONESIA
Authors: Sumarno Sumarno , Gimin Gimin 
Published: April 2020

This article aims to find out entrepreneurial education as a solution to the impact of the industrial era 4.0 (E.I.4.0). The data were collected by documentation techniques and observation, and then analyzed using descriptive exploratory techniques. The results indicate that E.I.4.0 had a negative impact is the loss of various jobs, but on the other hand had a positive impact, that are the emergence of business and employment opportunities. In E.I.4.0, human resources are required to have the ability to create, innovate, think critically, and collaborate and self-confidence. Entrepreneurship education provides knowledge and skills and develops attitudes that can be a solution to the impact of E.I 4.0. Entrepreneurial knowledge, skills and attitudes will shape human beings in accordance with E.I.4.0, which were the ability to create, innovate, think critically, collaborate, and be confident. This ability will be able to reach opportunities that arise in order to replace lost jobs. At the level of pre-school education, basic education and general secondary education (SMA/MA), entrepreneurship education should be emphasized more on developing entrepreneurial attitudes and knowledge. At the level of vocational secondary education (SMK/MAK) and higher education, entrepreneurship education should be emphasized more on the development of entrepreneurial skills. Effective implementation of entrepreneurship education for E.I.4.0 requires synergy and integration between subjects or subjects, teachers / lecturers, education levels, and among various stakeholders in a sustainable.

Keywords: Industrial era 4.0, entrepreneurship, entrepreneurship education.
PENGGUNAAN MEDIA PREZI UNTUK MENINGKATKAN MOTIVASI DAN HASIL BELAJAR SISWA PADA MATERI JURNAL PENYESUAIAN PERUSAHAAN DAGANG (Studi Kasus Pada Kelas XII IPS 2 SMA Negeri 4 Jember Tahun Ajaran 2018/2019)
Authors: Widyastuti Diah , Kartini Titin , Kantun Sri 
Published: April 2020

Penelitian ini bertujuan untuk mendeskripsikan penggunaan media Prezi dalam meningkatkan motivasi dan hasil belajar siswa kelas XII IPS 2 SMA Negeri 4 Jember pada materi jurnal penyesuaian perusahaan dagang semester genap tahun ajaran 2018/2019. Penelitian ini adalah Penelitian Tindakan Kelas (PTK) yang dilakukan sebanyak 2 siklus mulai dari tahap perencanaan, pelaksaan tindakan, observasi, dan refleksi. Subjek penelitian berjumlah 36 siswa kelas XII IPS 2 SMA Negeri 4 Jember. Metode pengumpulan data menggunakan metode observasi, tes, wawancara, dan dokumen. Analisis data yang digunakan secara deskriptif dengan pendekatan kualitatif. Hasil penelitian menunjukkan bahwa penggunaan media Prezi dapat meningkatkan motivasi dan hasil belajar siswa. Pada siklus I motivasi belajar siswa termasuk dalam kategori sedang dengan skor 1,2 dan mengalami peningkatan pada siklus II dengan skor 1,8 dalam kategori tinggi. Hasil belajar siswa pada siklus I sebesar 79,06 dengan ketuntasan klasikal sebesar 77,7% dan mengalami peningkatan menjadi 82,5 dengan ketuntasan klasikal sebesar 88,8% pada siklus II.
PEMASARAN RELASIONAL PADA TOKO IJEN DESA CINDOGO, KECAMATAN TAPEN, KABUPAEN BONDOWOSO.
Authors: Rizkianingsih Wira , Widodo Joko , Wahyuni Sri 
Published: April 2020

Penelitian ini bertujuan untuk mendeskripsikan pemasaran relasional untuk mempertahankan konsumen pada Toko Ijen Desa Cindogo Kecamatan Tapen Kabupaten Bondowoso. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Subjek dalam penelitian ini adalah pemilik toko Ijen, sedangkan informan penelitian yaitu konsumen dari toko ijen. Metode pengumpulan data yang digunakan yaitu observasi, wawancara dan dokumentasi. Analisis data yang digunakan yaitu reduksi data, penyajian data dan verifikasi data. Hasil penelitian ini menunjukkan bahwa Pemasaran Relasional pada Toko Ijen Desa Cindogo Kecamatan Tapen Kabupaten Bondowoso memiliki empat aspek dalam Pemasaran Relasional. Pemasaran Relasional yang dilakukan oleh toko Ijen yang Pertama adalah ikatan, Ikatan yang dilakukan oleh pemilik toko kepada konsumen, memberikan jika konsumen mau berhutang. Kedua kepedulian, kepedulian yang diberikan pemilik toko, Menginformasikan jauh-jauh hari jika toko tidak buka. Ketiga Hubungan Jangka Panjang, hubungan yang diberikan kepada konsumen, mengadakan tasyakuran bersama dengan konsumen. Keempat kepercayaan yang diberikan adalah, memberikan barang yang masa kadaluarsanya masih lama. dengan adanya keempat elemen tersebut membuat konsumen akan semakin loyal dengan barang yang diual di tempat tersebut. Dengan adanya pemasaran relasional yang dilakukan oleh pemilik toko Ijen mampu mempertahankan pelanggan sehingga toko Ijen mampu bertahan ditengah persaingan dengan toko-toko lain meskipun banyak yang menjual barang sejenis.
Periacetabular Osteotomy for Developmental Dysplasia of the Hip and Femoroacetabular Impingement
Authors: Holleyman Richard , Sohatee Mark Andrew , Witt Johan , Bankes Marcus J.K. , Andrade Tony J. , Board Tim , Lee Conroy Jonathan , Wilson Matthew , McBryde Callum , Khanduja Vikas , Malviya Ajay 
Published: April 2020

Background:
Periacetabular osteotomy (PAO) is a well-recognized procedure for the treatment of hip dysplasia in young adults and can be used for the surgical management of femoroacetabular impingement (FAI) with acetabular retroversion. The aim of this study was to use a national database to assess the outcomes of PAO for developmental dysplasia of the hip (DDH) and for FAI.

Methods:
All patients in whom an isolated PAO had been performed between January 2012 and February 2019 were identified in the Non-Arthroplasty Hip Registry (NAHR). Their outcomes were assessed using the EuroQol-5 Dimensions (EQ-5D) index and the International Hip Outcome Tool (iHOT)-12 preoperatively and then at 6 months, 12 months, and 2 years postoperatively.

Results:
Six hundred and thirty (630) PAOs were identified, with 558 (89%) performed for DDH and 72 (11%) performed for FAI. Most patients (90%) were female. The mean age in the DDH group (31.2 years) was significantly higher (p < 0.0001) than that in the FAI group (26.5 years). There were no other significant between-group demographic differences. Preoperatively and at each follow-up time-period, iHOT-12 scores were better in the DDH group than in the FAI group; however, only the preoperative scores differed significantly. There was significant improvement between the preoperative and 6-month iHOT-12 and EQ-5D index scores in both the DDH and the FAI group. This improvement was maintained at 12 months postoperatively, by which time almost 90% of the patients had achieved the minimum clinically important difference (MCID) in their iHOT-12 score.

Conclusions:
This study shows that PAO is a successful surgical intervention for DDH and FAI in the short term, with significant improvement in patient-reported outcome scores that is maintained up to 2 years postoperatively.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Analysing Iraqi Railways Network by Applying Specific Criteria Using the GIS Techniques
Authors: Et al. Naji 
Published: April 2020

The railways network is one of the huge infrastructure projects. Therefore, dealing with these projects such as analyzing and developing should be done using appropriate tools, i.e. GIS tools. Because, traditional methods will consume resources, time, money and the results maybe not accurate. In this research, the train stations in all of Iraq’s provinces were studied and analyzed using network analysis, which is one of the most powerful techniques within GIS. A free trial copy of ArcGIS®10.2 software was used in this research in order to achieve the aim of this study. The analysis of current train stations has been done depending on the road network, because people used roads to reach those train stations. The data layers for this study were collected and prepared to meet the requirements of network analyses within GIS. In this study, the current train stations in Iraq were analyzed and studied depending on accessibility value for those stations. Also, to know the numbers of people who can reach those stations within a walking time of 20 minutes. So, this study aims to analyze the current train stations according to multiple criteria by using network analysis in order to find the serviced areas around those stations. Results will be presented as digital maps layers with their attribute tables that show the beneficiaries from those train stations and serviced areas around those stations depending on specific criteria, with a view to determine the size of this problem and to support the decision makers in case of locating new train stations within the best locations for it.
Correlation Between Ischemia-Modified Albumin Level and Coronary Collateral Circulation
Authors: Chen Xin , Lin Yan , Tian Lihua , Wang Zhiquan 
Published: April 2020

Abstract
Objective: To investigate the correlation between ischemia-modified albumin (IMA) levels and coronary collateral circulation (CCC) in patients with chronic total occlusive (CTO). Methods: Coronary angiography was performed in the Department of Cardiology, Zhongnan Hospital of Wuhan University from 2017-08 to 2019-02 to identify 128 patients with CTO lesions in at least one major coronary artery. According to the Rentrop evaluation criteria, the degree of CCC formation was divided into the poor CCC formation group (Rentrop0-1 grade,n=69) and the good CCC formation group(Rentrop2-3 grade,n=59). The IMA level of the patients was measured using an albumin-cobalt binding assay. The general data, routine blood panel, total bilirubin (TBIL), blood lipids, uric acid (UA), left ventricular ejection fraction (LVEF) and other indicators of the patients were recorded and analyzed while assessing the patients' blood vessel occlusion. Results: The proportion of platelet count and diabetes in the poor CCC group was higher than that in the good CCC group (P<0.05). The ratio of ischemia-modified albumin and total bilirubin in the poor CCC group was lower than that in the good CCC group (P<0.05). Multivariate logistic regression analysis showed that ischemia-modified albumin was positively correlated with CCC formation [OR=1.190,95% CI(1.092-1.297),P<0.001], while diabetes was negatively correlated with CCC formation [OR=0.285,95% CI(0.094-0.864),P<0.05]. Ischemic modified albumin predicted good formation of CCC according to the ROC curve, and the area under the ROC curve was 0.769(95% CI:0.686-0.851，P＜0.001); the optimal cut-off value was 63.35 KU/L, and the sensitivity was 71.2%,specificity is 71%. Conclusion: The IMA level is closely related to good formation of CCC. Higher IMA levels can be used as an effective predictor of good CCC formation in patients with CTO.
Impact of the Ebola virus disease outbreak (2014-2016) on Tuberculosis Surveillance Activities in Guinea's National Tuberculosis Program: A Time Series Analysis
Authors: Magassouba Aboubacar Sidiki , Diallo Boubacar Djelo , Camara Lansana Mady , Sow Kadiatou , Camara Souleymane , Bah Boubacar , Barry Alpha Oumar , Diallo Thierno Hassane , Aboubacar Camara , Bangoura Adama Marie , Sow Oumou Younoussa 
Published: April 2020

Abstract
Background: Most countries in Subsaharan Africa have well-established National Tuberculosis Control Programs with relatively stable routine performances. However, major epidemiological events may result in significant disruptions. In March 2014, the World Health Organization announced the outbreak of Ebola virus disease in Guinea, a country with a high incidence of TB and HIV. Our study aims to assess the impact of the Ebola virus disease outbreak on TB notification, treatment and surveillance, using main indicators.Methods: This is a retrospective cohort study that compares TB trends using surveillance data from the periods before (2011-2013), during (2014-2016) and after (2017-2018) Ebola virus disease outbreak. A time series analysis is conducted to investigate the linkages between the decline in TB notification and the Ebola virus disease outbreak through cross-correlation. The lag in the cross-correlation test is evaluated using ANCOVA type II delayed variable dependent model. The surveillance system is assessed using TB surveillance standards and benchmarks and vital registration systems recommended by WHO, compared with those of 2015 during the Ebola virus disease.Results: The rate of reporting of TB declined from 120 cases per 100,000 in 2011 to 100 cases per 100,000 in 2014, at the peak of the Ebola virus disease outbreak. The time series cross-correlation test of all notified cases of TB and Ebola shows a significant lag of -0.4 (40%), reflecting a drop in the rate of notification (F-value=5.7 [95% CI: 0.2-21.3]). However, the Ebola virus disease had no negative impact on patient treatment outcomes (F-value=1.3 [95% CI: 0.002-8.8179]). Regarding the surveillance system, five out of 13 WHO standards and benchmarks were met following their evaluation in 2019, after the Ebola virus disease outbreak, compared to three in 2015.Conclusion: Major epidemics such as the Ebola virus disease outbreak may have a significant impact on well-established TB control programs as shown in the example of Guinea. On the other hand, it is noticed that, sudden disruptions of routine performance may lead programs to improve their surveillance system.
Application of Loop-Mediated Isothermal Amplification combined with colorimetric and lateral flow dipstick visualization as the potential point-of-care testing for Corynebacterium diphtheriae
Authors: Zasada Aleksandra Anna , Wiatrzyk Aldona , Czajka Urszula , Brodzik Klaudia , Formińska Kamila , Mosiej Ewa , Prygiel Marta , Krysztopa-Grzybowska Katarzyna , Wdowiak Karol 
Published: April 2020

Abstract
Background Diphtheria outbreaks occurred in endemic areas and imported and indigenous cases are reported in UE/EEA. Because of the high infectiveness and severity of the disease, early and accurate diagnosis of each suspected case is essential for the treatment and management of the case and close contacts. The aim of the study was to establish simple and rapid testing methods based on Loop-Mediated Isothermal Amplification (LAMP) assay for the detection of Corynebacterium diphtheriae and differentiation between toxigenic and non-toxigenic strains. Methods Corynebacterium diphtheriae and Corynebacterium ulcerans isolates from the National Institute of Public Health-National Institute of Hygiene collection were used for the development of LAMP assay for the diagnosis of diphtheria and nontoxigenic C. diphtheriae infections. Various colorimetric methods for visualization of results were investigated. Sensitivity and specificity of the assay were examined using a collection of DNA samples from various gram-positive and gram-negative bacteria. Results The LAMP assay for tox and dtxR genes was developed. The sensitivity and specificity of the assay were calculated as 100%. The detection limit was estimated as 1.42 pg/µl concentration of DNA template when the reaction was conducted for 60 min. However, the detection limit was lowered 10 times for every 10 minutes of reduction in the time of incubation during the reaction. Positive results were successfully detected colorimetrically using hydroxynaphthol blue, calcein, QuantiFluor, and lateral flow Milenia HybriDetect dipsticks. Conclusion The assay developed in the study might be applied for point-of-care testing of diphtheria and other C. diphtheriae infections as well as for other infections caused by diphtheria-toxin producing Corynebacterium species. It is highly sensitive, specific, inexpensive, easy to use, and suitable for low-resource settings.
The Relationship between Serum Levels of Vitamin C, Uric Acid and Antioxidant status with Coronary Artery Disease: a Case-Control Study
Authors: Torkzaban Aida , Naeini Seyed Amir Mansour Alavi , Hassanzadeh Akbar , Namdari Mehrdad 
Published: April 2020

Abstract
Background: Coronary Heart Disease (CHD) is among the main causes of death in adults. Increase of oxidative stress and defects in antioxidant defense play a major role in endothelium performance and are an effective factor in progress of atherosclerosis. The aim of this study is to measure the serum level of UA and vitamin C as well as the antioxidant status of CHD patients to evaluate their relationship and compare them with the healthy individual.Materials and methods: The present case-control study was performed on 44 cases and 44 controls. Demographic data and anthropometric indices were measured. Food frequency questionnaire (FFQ) and international physical activity questionnaire were also completed. After 12 hours of fasting, 10 ml blood was sampled from the participants. Uric acid (UA), vitamin C, TAC and MDA were also measured. The data were finally analyzed by SPSS Ver 22 software.Results: A significant difference was observed between the two groups in terms of uric acid (P<0.001) and vitamin C (P<0.03). However, mean MDA and TAC showed no significant difference between the two groups. The two groups’ difference in terms of vitamin A, E and beta carotene, zinc and selenium intake was not significant. A significant difference was however detected between the two groups in terms of vitamin C intake (P<0.047). A significant relationship was also observed between the systolic blood pressure and CHD (P<0.028).Conclusion: Our results suggest that increasing of serum uric acid and a decrease in serum vitamin C level can be considered as risk factors for CHD patients. Due to the lack of significant correlation between TAC and CHD in this study, it seems that different results will be obtained with increasing sample size.
Associations of Mitochondrial DNA 3777-4679 region mutations with maternally inherited essential hypertensive subjects in China.
Authors: Zhu Ye , You Jia , Xu Chao , Gu Xiang 
Published: April 2020

AbstractBackground:Nuclear genome or family mitochondrial screening system has become the hot focus of studies into essential hypertension. The role of mitochondrial DNA (mtDNA) in sporadic Chinese patients with hypertension has not been fully understood. The study was to evaluate the associations of mtDNA mutations with maternally inherited essential hypertensive subjects in China.Methods:From June 2009 to June 2016, a total of 800 gender-matched Chinese patients with maternally inherited essential hypertension (MIEH) and control group were 1:1 enrolled in this case-control study. Genomic DNA was extracted from each person's peripheral blood cells. The main mtDNA locations for MIEH were screened with oligodeoxynucleotides 3777-4679bp, analyzed and compared with the updated consensus Cambridge Sequence. Pathogenic mtDNA mutations were identified from the mitochondrial map.Results:MIEH subjects presented significantly higher values than those of control group in abdominal circumference(AC), waist circumference(WC), body mass index(BMI), fasting blood glucose(FBG), triglyceride(TG), low-density lipoprotein cholesterol (LDL) and renal function (P<0.05). MIEH subjects carried more amino acid changes and coding sequence variants (P<0.01) than control group. The allele frequencies of the eight single nucleotide polymorphisms(SNPs) were significantly different between the two groups, includingm.3970 C>T, m.4048G>A, m.4071C>T, m.4086C>T, m. 4164A>G and m.4248T>Cin ND1 gene, andm.4386T>Candm.4394C>Tin tRNAGlngene(P<0.001). Fifty-five homoplasmic or heteroplasmic mutations were detected in 5 genes: ND1, tRNAIle, tRNAMet, tRNAGlnand ND2 gene. The ND1 gene was the main mutation site, where the most mtDNA mutation wasm.3970 C>T.Conclusions:The mtDNA mutations were involved in the process of MIEH. We identified mitochondrial genetic characteristics in MIEH patients in China. The present research serves as a solid foundation for further detailed research on the association between MIEH and mitochondrial dysfunction, and their causal relationship in Chinese and other populations with a similar lifestyle.