bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sex Differences in Problem Alcohol Use in High School as a Function of Recent Sexual Violence Victimization or Perpetration
Authors: Badour Christal L. , Bell Samuel C. , Clear Emily R. , Bush Heather M. , Coker Ann L. 
Published: December 2019

AbstractTo investigate sex differences in associations between sexual violence victimization (SVV), sexual violence perpetration (SVP), and binge drinking and/or alcohol problems among high school students. While SVV has been linked to problem alcohol use among young women, little research has addressed the unique associations of SVV and SVP on alcohol use/problems within both sexes. A cross-sectional analysis of 16,992 high school students’ self-reports of past-year SVP and SVV was used where SVV/SVP was defined by three tactics (sexual coercion, drug/alcohol-facilitated or incapacitated sex, and physically forced sex). Alcohol measures included past-month binge drinking and past-year alcohol problems. Rates of SVV were twice as high in females (21.2% vs. 13.3%), and SVP rates were twice as high in males (10.9% vs. 5.2%). SVV and SVP were each associated with an increased rate of current binge drinking and problem alcohol use for both sexes, across increasing numbers of SV tactics and within each of three tactics. After controlling for demographic and other risk factors including SVP, drug/alcohol-facilitated or incapacitated SVV was more strongly linked to binge drinking and alcohol problems among females. SVP was more strongly linked to binge drinking and alcohol problems among males (adjusting for SVV and other covariates). No sex differences emerged in associations between coerced or physically forced SVV/SVP and alcohol-related outcomes. Both SVV and SVP are associated with an increased likelihood of binge drinking and alcohol problems for males and females. Important sex differences emerged when SV tactics are considered.
Analytical Three-dimensional Magnetohydrostatic Equilibrium Solutions for Magnetic Field Extrapolation Allowing a Transition from Non-force-free to Force-free Magnetic Fields
Authors: Neukirch Thomas , Wiegelmann Thomas 
Published: December 2019

AbstractFor the extrapolation of magnetic fields into the solar corona from measurements taken in the photosphere (or chromosphere) force-free magnetic fields are typically used. This does not take into account that the lower layers of the solar atmosphere are not force-free. While some numerical extrapolation methods using magnetohydrostatic magnetic fields have been suggested, a complementary and numerically comparatively cheap method is to use analytical magnetohydrostatic equilibria to extrapolate the magnetic field. In this paper, we present a new family of solutions for a special class of analytical three-dimensional magnetohydrostatic equilibria, which can be of use for such magnetic field extrapolation. The new solutions allow for the more flexible modeling of a transition from non-force-free to (linear) force-free magnetic fields. In particular, the height and width of the region where this transition takes place can be specified by choosing appropriate model parameters.
Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions
Authors: Banse Stephen A. , Lucanic Mark , Sedore Christine A. , Coleman-Hulbert Anna L. , Plummer W. Todd , Chen Esteban , Kish Jason L. , Hall David , Onken Brian , Presley Michael P. , Jones E. Grace , Blue Benjamin W. , Garrett Theo , Abbott Mark , Xue Jian , Guo Suzhen , Johnson Erik , Foulger Anna C. , Chamoli Manish , Falkowski Ron , Melentijevic Ilija , Harinath Girish , Huynh Phu , Patel Shobhna , Edgar Daniel , Jarrett Cody M. , Guo Max , Kapahi Pankaj , Lithgow Gordon J. , Driscoll Monica , Phillips Patrick C. 
Published: December 2019

AbstractThe goal of the Caenorhabditis Intervention Testing Program is to identify robust and reproducible pro-longevity interventions that are efficacious across genetically diverse cohorts in the Caenorhabditis genus. The project design features multiple experimental replicates collected by three different laboratories. Our initial effort employed fully manual survival assays. With an interest in increasing throughput, we explored automation with flatbed scanner-based Automated Lifespan Machines (ALMs). We used ALMs to measure survivorship of 22 Caenorhabditis strains spanning three species. Additionally, we tested five chemicals that we previously found extended lifespan in manual assays. Overall, we found similar sources of variation among trials for the ALM and our previous manual assays, verifying reproducibility of outcome. Survival assessment was generally consistent between the manual and the ALM assays, although we did observe radically contrasting results for certain compound interventions. We found that particular lifespan outcome differences could be attributed to protocol elements such as enhanced light exposure of specific compounds in the ALM, underscoring that differences in technical details can influence outcomes and therefore interpretation. Overall, we demonstrate that the ALMs effectively reproduce a large, conventionally scored dataset from a diverse test set, independently validating ALMs as a robust and reproducible approach toward aging-intervention screening.
Probabilistic assessment of nectar requirements for nectar-foraging honey bees
Authors: Rodney Sara , Kramer Vincent J. 
Published: December 2019

AbstractRecent concerns regarding potential effects of pesticides on pollinators have prompted regulatory agencies to estimate dietary ingestion rates for honey bees (Apis mellifera). The task is difficult because of the complex caste and food storage systems in honey bee colonies. Considerable data on the nutrition and energetics of honey bees have recently been collated. These data were used to parameterize a probabilistic model estimating nectar requirements of nectar foragers. Median estimates were more than 6× lower than the recommended median value from the North American government agencies, of 292 mg nectar/bee/day. The distribution of estimates had much greater variability than those of the agencies. The differences are due primarily to the disparate assumptions regarding how much time nectar foragers spend flying and foraging. Risk assessors considering honey bee dietary exposure should take account of current and emerging data providing insight into nectar forager dietary requirements, foraging activity, and feeding behavior.
Sex Hormones as Cognitive Enhancers?
Authors: Núñez Francisco , Maraver María J. , Colzato Lorenza S. 
Published: December 2019

AbstractUnderstanding the differences in the way women and men think has made headway thanks to experiments showing how sex hormones influence cognitive capacities. Masculine and feminine sex hormones (androgens and estrogens, respectively) affect cognition in different ways and may account for some of the gender differences in cognitive abilities, allowing men and women to perform better in certain cognitive tests. In this opinion article, we discuss studies addressing differences in cognitive functions between males and females and the underlying neural substrates, as well as the effects of sex hormone supplementation. Even though some studies on patients receiving exogenous sex hormones showed gender differences that emerge at group levels on a few cognitive tasks, it is not yet clear whether these differences can be partially attributed to hormonal causes. Supplementation of female estrogen can enhance verbal skills, whereas masculine androgen can increase performance in mathematical and visuospatial tasks. Studies of the administration of exogenous sex hormones have allowed further insight into the use of sex hormones as possible cognitive enhancers.
Mass balance and area changes of glaciers in the Cordillera Real and Tres Cruces, Bolivia, between 2000 and 2016
Authors: Seehaus Thorsten , Malz Philipp , Sommer Christian , Soruco Alvaro , Rabatel Antoine , Braun Matthias 
Published: December 2019

AbstractClimate change has led to a significant shrinkage of glaciers in the Tropical Andes during the last decades. Recent multi-temporal quantifications of ice mass loss at mountain range to regional scale are missing. However, this is fundamental information for future water resource planning and glacier change projections. In this study, we measure temporally consistent glacier area changes and geodetic mass balances throughout the Bolivian Cordillera Real and Tres Cruces based on multi-sensor remote-sensing data. By analyzing multi-spectral satellite images and interferometric SAR data, a glacier recession of 81 ± 18 km2 (29%; 5.1 ± 1.1 km2 a−1), a geodetic mass balance of −403 ± 78 kg m−2 a−1 and a total ice mass loss of 1.8 ± 0.5 Gt is derived for 2000–2016. In the period 2013–2016, ice mass loss was 21% above the average rate. A retreat rate of 15 ± 5 km2 a−1 and a mass budget of −487 ± 349 kg m−2 a−1 are found in this more recent period. These higher change rates can be attributed to the strong El Niño event in 2015/16. The analyses of individual glacier changes and topographic variables confirmed the dependency of the mass budget and glacier recession on glacier aspect and median elevation.
Late-stage tectonic evolution of the Al-Hajar Mountains, Oman: new constraints from Palaeogene sedimentary units and low-temperature thermochronometry
Authors: Corradetti A , Spina V , Tavani S , Ringenbach JC , Sabbatino M , Razin P , Laurent O , Brichau S , Mazzoli S 
Published: December 2019

AbstractMountain building in the Al-Hajar Mountains (NE Oman) occurred during two major shortening stages, related to the convergence between Africa–Arabia and Eurasia, separated by nearly 30 Ma of tectonic quiescence. Most of the shortening was accommodated during the Late Cretaceous, when northward subduction of the Neo-Tethys Ocean was followed by the ophiolites obduction on top of the former Mesozoic margin. This shortening event lasted until the latest Santonian – early Campanian. Maastrichtian to Eocene carbonates unconformably overlie the eroded nappes and seal the Cretaceous foredeep. These neo-autochthonous post-nappe sedimentary rocks were deformed, along with the underlying Cretaceous tectonic pile, during the second shortening event, itself including two main exhumation stages. In this study we combine remotely sensed structural data, seismic interpretation, field-based structural investigations and apatite (U–Th)/He (AHe) cooling ages to obtain new insights into the Cenozoic deformation stage. Seismic interpretation indicates the occurrence of a late Eocene flexural basin, later deformed by an Oligocene thrusting event, during which the post-nappe succession and the underlying Cretaceous nappes of the internal foredeep were uplifted. This stage was followed by folding of the post-nappe succession during the Miocene. AHe data from detrital siliciclastic deposits in the frontal area of the mountain chain provide cooling ages spanning from 17.3 to 42 Ma, consistent with available data for the structural culminations of Oman. Our work points out how renewal of flexural subsidence in the foredeep and uplift of the mountain belt were coeval processes, followed by layer-parallel shortening preceding final fold amplification.
Beings in the moment
Authors: Elliott Mark A. 
Published: December 2019

AbstractHoerl & McCormack's theory defines temporal behavior from an awareness of time, but lacks one critical element: the impact of “psychological presence” in the “moment now.” Central to experience of temporal non-stationarity: “Nowness” links future with past in the context of time flow. Does this differ between species? Evidence suggests not: Different temporal experiences between species requires greater critical evaluation.
Thinking about time and number: An application of the dual-systems approach to numerical cognition
Authors: Lohse Karoline , Sixtus Elena , Lonnemann Jan 
Published: December 2019

Abstract
Based on the notion that time, space, and number are part of a generalized magnitude system, we assume that the dual-systems approach to temporal cognition also applies to numerical cognition. Referring to theoretical models of the development of numerical concepts, we propose that children's early skills in processing numbers can be described analogously to temporal updating and temporal reasoning.
The “now moment” is believed privileged because “now” is when happening is experienced
Authors: Kenward Ben , Pilling Michael 
Published: December 2019

Abstract
Hoerl & McCormack risk misleading people about the cognitive underpinnings of the belief in a privileged “now moment” because they do not explicitly acknowledge that the sense of existing in the now moment is an intrinsically temporally dynamic one. The sense of happening that is exclusive to the now moment is a better candidate for the source of belief in a privileged now.
The Neuropsychological Profile of Mild Cognitive Impairment in Lewy Body Dementias
Authors: Ciafone Joanna , Little Bethany , Thomas Alan J. , Gallagher Peter 
Published: December 2019

AbstractObjectives:Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) have substantial clinical and biological overlap, with cognitive deficits typically observed in the executive and visuospatial domains. However, the neuropsychological profiles of mild cognitive impairment (MCI) associated with these disorders are not well understood.Methods:This systematic review examined existing literature on cognition in MCI due to LB disease (MCI-LB) and PD (PD-MCI) using an electronic search of seven databases (Medline, Embase, Psychinfo, PubMed, ProQuest, Scopus, and ScienceDirect). MCI-LB results were reviewed narratively given the small number of resulting papers (n = 7). Outcome variables from PD-MCI studies (n = 13) were extracted for meta-analysis of standardised mean differences (SMD).Results:In MCI-LB, executive dysfunction and slowed processing speed were the most prominent impairments, while visuospatial and working memory (WM) functions were also poor. MCI-LB scored significantly lower on verbal memory tests relative to controls, but significantly higher than patients with MCI due to Alzheimer’s disease. Quantitative analysis of studies in PD-MCI showed a similar profile of impairment, with the largest deficits in visuospatial function (Benton Judgement of Line Orientation, SMD g = −2.09), executive function (Trail Making Test B, SMD g = −1.65), verbal ability (Naming Tests, SMD g = −0.140), and WM (Trail Making Test A, SMD g = −1.20). In both MCI-LB and PD-MCI, verbal and visuospatial memory retrieval was impaired, while encoding and storage appeared relatively intact.Conclusions:The findings of this systematic review indicate similar neuropsychological profiles in the MCI stages of DLB and PDD. Executive impairment may at least partially explain poor performance in other domains.
Anarchistic action. Social organization and dynamics in southern Scandinavia from the Iron Age to the Middle Ages
Authors: Borake Trine Louise 
Published: December 2019

AbstractA general interest in centralized institutions, state formation and prestige objects has dominated research on social organization and dynamics in Scandinavia from the Late Iron Age to the Middle Ages. Accordingly, a focus on kingly power, aristocratic influence, hierarchies and warrior might has dominated archaeological research designs for the last forty years. Subsequently, other perspectives have been evaded and their significance has been diminished. In this article, I use anarchistic principles as an analytic perspective and present examples of anarchistic actions – network organization, justified leaders and decentralization – drawing on well-known but ambiguous phenomena such as thing sites, the southern Danish defence system Danevirke, and migration and mobility. I suggest a perspective that recognizes resistance, authority and decentralization as well as centralization and institutionalization, allowing a broad spectrum of social engagement and interrelations to influence social organization. I will argue that human intentionality has been overlooked in favour of structures and institutions, and that the power of network organization and decentralization is influential in shaping social organization and dynamics.
Evaluation and Comparison of MODIS Collection 6.1 and Collection 6 Dark Target Aerosol Optical Depth over Mainland China Under Various Conditions Including Spatiotemporal Distribution, Haze Effects, and Underlying Surface
Authors: Huang Y. , Zhu B. , Zhu Z. , Zhang T. , Gong W. , Ji Y. , Xia X. , Wang L. , Zhou X. , Chen D. 
Published: December 2019

AbstractModifications such as degrading the retrieval quality of mixed pixels in the coastline area and revising surface characterization scheme have been made to the Moderate Resolution Imaging Spectroradiometer (MODIS) Collection 6.1 (C6.1) Dark Target (DT) aerosol optical depth (AOD) product to address inaccuracy over urban areas. In this study, comprehensive evaluations of modifications to the MODIS C6.1 DT AOD product, in comparison with Collection 6 (C6), are conducted over mainland China under different spatial distributions, seasons, and air quality for the period 2010–2017, combined with validation against Aerosol Robotic Network (AERONET) AOD measurements. The preliminary result showed that the C6.1 DT AOD product in China displayed an overall good performance with high R2 (0.87) and low root‐mean‐square error (0.23) against ground measurements. Moreover, the C6.1 DT AOD product was an overall improvement over C6, with greater correlation and lower uncertainty against ground measurements, especially for the North China Plain and Central China, although this was not the case for Western China. The improvement was also seasonal, being distinct in spring but less pronounced in winter, and negatively correlated with the level of air pollution. Furthermore, the analysis of DT AOD retrievals in different urbanized areas illustrated that the updated DT algorithm worked well in completely urbanized areas, where 97% of C6.1 DT AOD retrievals were an improvement over C6, while approximately 10% of C6.1 DT AOD retrievals were deteriorated in semiurbanized areas. Additionally, the DT AOD retrievals in areas with relatively low enhanced vegetation index and high surface reflectance were significantly improved, mitigating problems associated with the DT algorithm, further improving the reliability of MODIS DT AOD products.
Implementation of a Modified Adaptive Covariance Inflation Scheme for the Big Data‐Driven NLS‐4DVar Algorithm
Authors: Tian Xiangjun , Zhang Hongqin 
Published: December 2019

AbstractThe adaptive inflation scheme is critical for avoiding underestimation of ensemble‐estimated error variances. In this study, we expanded a spatially and temporally varying adaptive inflation scheme proposed within the framework of the local ensemble transform Kalman filter to a global version to facilitate its application in four‐dimensional ensemble‐variational (4DEnVar) data assimilation methods. We adopted an efficient local correlation matrix decomposition approach to enhance its computation efficiency and then implemented the modified adaptive inflation scheme using the big data‐driven nonlinear least squares 4‐D variational (BD‐NLS4DVar) data assimilation method to improve its robustness. The ensemble analysis scheme of the BD‐NLS4DVar method with the modified adaptive inflation scheme was able to adjust the ensemble spreads and error covariances more accurately. Several groups of observing system simulation experiments based on 2‐D shallow‐water equations demonstrated that the BD‐NLS4DVar method implemented with the modified adaptive inflation scheme provides some performance improvement over the standard BD‐NLS4DVar method with no inflation.
Dynamic Stressing of Naturally Fractured Rocks: On the Relation Between Transient Changes in Permeability and Elastic Wave Velocity
Authors: Shokouhi Parisa , Jin Jiang , Wood Clay , Rivière Jacques , Madara Benjamin , Elsworth Derek , Marone Chris 
Published: December 2019

AbstractWe report on laboratory experiments designed to explore the fundamental processes that impact fluid permeability during drilling and fluid injection. Coupled ultrasonic and permeability measurements are presented for Westerly granite samples fractured in situ and used to illuminate the relationship between nonlinear dynamic stiffness and fracture permeability indexed via fracture aperture. We perturb the effective stress field using normal stress and pore pressure oscillations. The velocity of ultrasonic waves transmitted across the fracture is used to infer the evolution of elastic properties and the fracture nonlinearity. Changes in permeability are measured concurrently. We observe that relative changes in wave velocity and permeability, due to both normal stress and pore pressure oscillations, are correlated, such that larger drops in wave velocity (higher nonlinearity) correspond to larger increases in permeability. Our observations suggest that dynamic stressing is more likely to enhance the permeability of fractures that exhibit greater nonlinearity.
Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer
Authors: Berndt Nikolaus , Egners Antje , Mastrobuoni Guido , Vvedenskaya Olga , Fragoulis Athanassios , Dugourd Aurélien , Bulik Sascha , Pietzke Matthias , Bielow Chris , van Gassel Rob , Damink Steven W. Olde , Erdem Merve , Saez-Rodriguez Julio , Holzhütter Hermann-Georg , Kempa Stefan , Cramer Thorsten 
Published: December 2019

Abstract
Background
Metabolic alterations can serve as targets for diagnosis and cancer therapy. Due to the highly complex regulation of cellular metabolism, definite identification of metabolic pathway alterations remains challenging and requires sophisticated experimentation.

Methods
We applied a comprehensive kinetic model of the central carbon metabolism (CCM) to characterise metabolic reprogramming in murine liver cancer.

Results
We show that relative differences of protein abundances of metabolic enzymes obtained by mass spectrometry can be used to assess their maximal velocity values. Model simulations predicted tumour-specific alterations of various components of the CCM, a selected number of which were subsequently verified by in vitro and in vivo experiments. Furthermore, we demonstrate the ability of the kinetic model to identify metabolic pathways whose inhibition results in selective tumour cell killing.

Conclusions
Our systems biology approach establishes that combining cellular experimentation with computer simulations of physiology-based metabolic models enables a comprehensive understanding of deregulated energetics in cancer. We propose that modelling proteomics data from human HCC with our approach will enable an individualised metabolic profiling of tumours and predictions of the efficacy of drug therapies targeting specific metabolic pathways.