bluuebunny/crossref_metadata_2025_split huggingface dataset:
Xylanase increased the energetic contribution of fiber and improved the oxidative status, gut barrier integrity, and growth performance of growing pigs fed insoluble corn-based fiber
Authors: Petry Amy L , Huntley Nichole F , Bedford Michael R , Patience John F 
Published: July 2020

Abstract
The experimental objective was to investigate the impact of xylanase on the bioavailability of energy, oxidative status, and gut function of growing pigs fed a diet high in insoluble fiber and given a longer adaptation time than typically reported. Three replicates of 20 gilts with an initial body weight (BW) of 25.43 ± 0.88 kg were blocked by BW, individually housed, and randomly assigned to one of four dietary treatments: a low-fiber control (LF) with 7.5% neutral detergent fiber (NDF), a 30% corn bran without solubles high-fiber control (HF; 21.9% NDF), HF + 100 mg/kg xylanase (HF + XY; Econase XT 25P), and HF + 50 mg/kg arabinoxylan-oligosaccharide (HF + AX). Gilts were fed ad libitum for 36 d across two dietary phases. Pigs and feeders were weighed on days 0, 14, 27, and 36. On day 36, pigs were housed in metabolism crates for a 10-d period, limit fed (80% of average ad libitum intake), and feces and urine were collected the last 72 h to determine the digestible energy (DE) and metabolizable energy (ME). On day 46, serum and ileal and colonic tissue were collected. Data were analyzed as a linear mixed model with block and replication as random effects, and treatment, time, and treatment × time as fixed effects. There was a significant treatment × time interaction for BW, average daily gain (ADG), and gain to feed (G:F; P &lt; 0.001). By design, BW at day 0 did not differ; at day 14, pigs fed LF were 3.5% heavier, and pigs fed HF + XY, when compared with HF, were 4% and 4.2% heavier at days 27 and 36, respectively (P &lt; 0.001). From day 14 to 27 and day 27 to 36, when compared with HF, HF + XY improved ADG by 12.4% and 10.7% and G:F by 13.8% and 8.8%, respectively (P &lt; 0.05). Compared with LF, HF decreased DE and ME by 0.51 and 0.42 Mcal/kg, respectively, but xylanase partially mitigated that effect by increasing DE and ME by 0.15 and 0.12 Mcal/kg, over HF, respectively (P &lt; 0.05). Pigs fed HF + XY had increased total antioxidant capacity in the serum and ileum (P &lt; 0.05) and tended to have less circulating malondialdehyde (P = 0.098). Pigs fed LF had increased ileal villus height, and HF + XY and HF + AX had shallower intestinal crypts (P &lt; 0.001). Pigs fed HF + XY had increased ileal messenger ribonucleic acid abundance of claudin 4 and occludin (P &lt; 0.05). Xylanase, but not AX, improved the growth performance of pigs fed insoluble corn-based fiber. This was likely a result of the observed increase in ME, improved antioxidant capacity, and enhanced gut barrier integrity, but it may require increased adaptation time to elicit this response.
Multiple Coexisting Species and the First Known Case of a Cheater in Epicephala (Gracillariidae) Associated with a Species of Glochidion (Phyllanthaceae) in Tropical Asia
Authors: Wang Zhibo , Yang Xiaofei , Zhang Zhenguo , Shi Fuchen , Li Houhun 
Published: July 2020

Abstract
Glochidion plants and Epicephala moths played different roles and kept the balance in the mutualism. We studied the four coexisting Epicephala species on Glochidion sphaerogynum in detail and reconstructed the phylogenic tree of 40 Gracillariidae species. The results showed that one of them (Epicephala impolliniferens) did not pollinate G. sphaerogynum, because of lacking the specialized structure of carrying pollen. These results suggested that E. impolliniferens acted as a ‘cheater’ in the system. The phylogenetic analyses suggested that E. impolliniferens derived from a pollinating species, and had secondarily gave up the ability to pollinate. This is a typical phenomenon of mutualism reversal. The phenomenon exhibits the co-evolutionary diversification under selection pressures.
Shielding effect of radiation dose reduction fiber during the use of C-arm fluoroscopy: a phantom study
Authors: Cha Hyemi , Lee Kisung , Park Moon Seok , Lee Kyoung Min , Cho Kyeyoung , Sung Ki Hyuk 
Published: July 2020

ABSTRACT
This study evaluated the shielding effect of a newly developed dose-reduction fiber (DRF) made from barium sulfate, in terms of radiation doses delivered to patients’ radiosensitive organs and operator during C-arm fluoroscopy and its impact on the quality of images. A C-arm fluoroscopy unit was placed beside a whole-body phantom. Radiophotoluminescent glass dosimeters were attached to the back and front of the whole-body phantom at 20 cm intervals. Radiation doses were measured without DRF and with it applied to the back (position 1), front (position 2) or both sides (position 3) of the phantom. To investigate the impact of DRF on the quality of fluoroscopic images, step-wedge and modulation transfer function phantoms were used. The absorbed radiation doses to the back of the phantom significantly decreased by 25.3–88.8% after applying DRF to positions 1 and 3. The absorbed radiation doses to the front of the phantom significantly decreased by 55.3–93.6% after applying DRF to positions 2 and 3. The contrast resolution values for each adjacent step area fell in the range 0.0119–0.0209, 0.0128–0.0271, 0.0135–0.0339 and 0.0152–0.0339 without and with DRF applied to positions 1, 2 and 3, respectively. The investigated DRF effectively reduces absorbed radiation doses to patients and operators without decreasing the quality of C-arm fluoroscopic images. Therefore, routine clinical use of the DRF is recommended during the use of C-arm fluoroscopy.
Factors associated with the intention to participate in activities during a nuclear disaster situation among firefighters
Authors: Iyama Keita , Takano Yoshinori , Takahashi Tsukasa , Hasegawa Arifumi 
Published: July 2020

Abstract
Willingness to participate in activities during a nuclear disaster situation among firefighters is low. Thus, we aimed to identify the factors affecting the intention to participate in nuclear disaster activities. A questionnaire survey was conducted among firefighter training students (n = 186) and firefighters (n = 410), and a multivariate logistic regression analysis was performed to identify factors affecting the intention to participate in nuclear disaster activities. The percentage of students and firefighters who were willing to participate in nuclear disaster activities was 70.4% (n = 131) and 56.3% (n = 231) (P &lt; 0.01), respectively. The factors affecting the students’ intention to participant were “wish to learn more information about radiation” and “firefighters should actively work in a nuclear disaster.” Meanwhile, the factors affecting the firefighters’ intention to work were “have self-confidence during nuclear disaster activities,” “participate if there is an incentive,” “unable to get a family member to understand the need to participate in a nuclear disaster activity,” and marital status. A student’s decision might be strongly connected to social norms about participating in nuclear disaster activities. The willingness to participate in nuclear disaster activities among firefighters might be improved by facilitating activities that can build their self-confidence, providing sufficient incentives, and helping their families understand their work. Therefore, not only direct education for responders but also educational activities for the general public and their families are essential.
Beaming as an explanation of the repetition/width relation in FRBs
Authors: Connor L , Miller M C , Gardenier D W 
Published: July 2020

ABSTRACT
It is currently not known if repeating fast radio bursts (FRBs) are fundamentally different from those that have not been seen to repeat. One striking difference between repeaters and apparent non-repeaters in the Canadian Hydrogen Intensity Mapping Experiment sample is that the once-off events are typically shorter in duration than sources that have been detected two or more times. We offer a simple explanation for this discrepancy based on a selection effect due to beamed emission, in which highly beamed FRBs are less easily observed to repeat, but are abundant enough to detect often as once-off events. The explanation predicts that there is a continuous distribution of burst duration – not a static bimodal one – with a correlation between repetition rate and width. Pulse width and opening angle may be related by relativistic effects in shocks, where short-duration bursts have small solid angles due to a large common Lorentz factor. Alternatively, the relationship could be a geometric effect where narrow beams sweep past the observer more quickly, as with pulsars. Our model has implications for the FRB emission mechanism and energy scale, volumetric event rates, and the application of FRBs to cosmology.
Thermalization of large energy release in the early Universe
Authors: Chluba Jens , Ravenni Andrea , Acharya Sandeep Kumar 
Published: July 2020

ABSTRACT
Spectral distortions of the cosmic microwave background (CMB) provide a unique tool for learning about the early phases of cosmic history, reaching deep into the primordial Universe. At redshifts z ≲ 106, thermalization processes become inefficient and existing limits from COBE/FIRAS imply that no more than Δρ/ρ ≲ 6 × 10−5 ($95{{\ \rm per\ cent}}$ c.l.) of energy could have been injected into the CMB. However, at higher redshifts, when thermalization is efficient, the constraint weakens and Δρ/ρ ≃ 0.01−0.1 could in principle have occurred. Existing computations for the evolution of distortions commonly assume Δρ/ρ ≪ 1 and thus become inaccurate in this case. Similarly, relativistic temperature corrections become relevant for large energy release, but have previously not been modelled as carefully. Here, we study the evolution of distortions and the thermalization process after single large energy release at z ≳ 105. We show that for large distortions the thermalization efficiency is significantly reduced and that the distortion visibility is sizeable to much earlier times. This tightens spectral distortions constraints on low-mass primordial black holes with masses $M_{\rm PBH}\lesssim 2 \times 10^{11}\, {\rm g}$. Similarly, distortion limits on the amplitude of the small-scale curvature power spectrum at wavenumbers $k\gtrsim 10^4\, {\rm Mpc}^{-1}$ and short-lived decaying particles with lifetimes $t_X\lesssim 10^7\, {\rm s}$ are tightened, however, these still require a more detailed time-dependent treatment. We also briefly discuss the constraints from measurements of the effective number of relativistic degrees of freedom and light element abundances and how these complement spectral distortion limits.
Management and Outcome of Left Ventricular Assist Device Infections in Patients Undergoing Cardiac Transplantation
Authors: Esquer Garrigos Zerelda , Castillo Almeida Natalia E , Gurram Pooja , Vijayvargiya Prakhar , Corsini Campioli Cristina G , Stulak John M , Rizza Stacey A , Baddour Larry M , Sohail M Rizwan 
Published: July 2020

Abstract

Background
Post-operative management of patients undergoing cardiac transplantation with an infected left ventricular assist device (LVAD) is unclear.

Methods
We retrospectively screened all adults with an LVAD who underwent cardiac transplantation at our institution from 2010 through 2018. We selected all cases of LVAD-specific and LVAD-related infections who were receiving antimicrobial therapy as initial treatment course or chronic suppression at the time of cardiac transplantation. Non-LVAD infections, superficial driveline-infection, or concurrent use of right ventricular assist device or extracorporeal membrane oxygenation device were excluded.

Results
A total of 54 cases met study criteria with 18/54 (33.6%) classified as LVAD- specific or related infections and 36/54 (66.6%) as non-infected. Cases of LVAD-infection had a higher median Charlson Comorbidity Index score at the time of transplantation compared to non-infected cases (P=.005). Of the 18 cases of infection, 13/18 (72.2%) were classified as LVAD-specific and 5/18 (27.8%) as LVAD-related. A total of 9/13 (69.2%) cases had proven LVAD-specific infections. Antimicrobial therapy was extended post-transplant to treat preceding LVAD-specific infection in all nine cases (9/13, 69.2%) with a median duration of 14 days (IQR 14-28). Following LVAD removal, antimicrobial treatment was not continued for preceding LVAD-related infections.

Conclusions
Patients with an LVAD-specific infection were treated with two weeks of pathogen-directed therapy post heart transplant without any relapses. For those without LVAD-specific infection or uncomplicated LVAD-related bacteremia who had completed antimicrobial therapy pre-transplant, antibiotics were discontinued after standard peri-operative prophylaxis and no relapses were observed.
Laser Interstitial Thermal Therapy in the Treatment of Thalamic Brain Tumors: A Case Series
Authors: Murayi Roger , Borghei-Razavi Hamid , Barnett Gene H , Mohammadi Alireza M 
Published: July 2020

Abstract

BACKGROUND
Surgical options for patients with thalamic brain tumors are limited. Traditional surgical resection is associated with a high degree of morbidity and mortality. Laser interstitial thermal therapy (LITT) utilizes a stereotactically placed laser probe to induce thermal damage to tumor tissue. LITT provides a surgical cytoreduction option for this challenging patient population. We present our experience treating thalamic brain tumors with LITT.

OBJECTIVE
To describe our experience and outcomes using LITT on patients with thalamic tumors.

METHODS
We analyzed 13 consecutive patients treated with LITT for thalamic tumors from 2012 to 2017. Radiographic, clinical characteristics, and outcome data were collected via review of electronic medical records

RESULTS
Thirteen patients with thalamic tumors were treated with LITT. Most had high-grade gliomas, including glioblastoma (n = 9) and anaplastic astrocytoma (n = 2). The average tumor volume was 12.0 cc and shrank by 42.9% at 3 mo. The average hospital stay was 3.0 d. Median ablation coverage as calculated by thermal damage threshold (TDT) lines was 98% and 95% for yellow (>43°C for >2 min) or blue (>10 min), respectively. Median disease-specific progression-free survival calculated for 8 patients in our cohort was 6.1 mo (range: 1.1-15.1 mo). There were 6 patients with perioperative morbidity and 2 perioperative deaths because of intracerebral hematoma.

CONCLUSION
LITT is a feasible treatment for patients with thalamic tumors. LITT offers a cytoreduction option in this challenging population. Patient selection is key. Close attention should be paid to lesion size to minimize morbidity. More studies comparing treatment modalities of thalamic tumors need to be performed.
Promoting Physical Activity via Telehealth in People With Parkinson Disease: The Path Forward After the COVID-19 Pandemic?
Authors: Quinn Lori , Macpherson Chelsea , Long Katrina , Shah Hiral 
Published: July 2020

Abstract

Objective
There is mounting evidence in support of exercise and physical activity as a first-line approach to managing symptoms and potentially altering disease progression in people with Parkinson disease (PD). For many patients, a critical gap is the need for expert guidance to overcome barriers, set realistic goals, and provide personalized advice to optimize exercise uptake and adherence. The purpose of this case report is to describe a physical activity coaching program (Engage-PD) for individuals newly diagnosed with PD and to highlight rapid modifications made to this program in response to the COVID-19 pandemic.

Methods (Case Description)
Engage-PD is a single cohort implementation study of a coaching intervention grounded in self-determination theory being conducted at Columbia University Parkinson’s Foundation Center of Excellence in New York City, NY (USA), the early epicenter of the COVID-19 pandemic in the United States. The project was uniquely positioned to be adapted to telehealth delivery and to address an immediate need for support and guidance in the home environment, including people with early-mid–stage PD. Participants completed baseline and follow-up (3 months) assessments and participated in up to 4 coaching sessions, all delivered via a telehealth platform. The intervention incorporated 1:1 coaching, goal-setting, physical activity monitoring, and use of a disease-specific workbook to promote and support safe exercise uptake.

Results
While the program is ongoing, 52 referrals were received and 27 individuals with PD enrolled in the first 2 months of the pandemic for a recruitment rate of 52%. Although direct comparisons with pre-coronavirus recruitment are difficult due to the recency of the Engage-PD implementation study, this recruitment rate was larger than expected, which may have been due to several factors (eg, most patients had limited, if any, access to in-person programs and therapy services during this time, so the Engage program filled an immediate need to provide exercise and activity guidance). There was a wide range of scores for both baseline physical activity and self-efficacy measures.

Conclusion
Remotely delivered interventions may serve as a sustainable platform for physical activity coaching programs for people with PD as well as other neurodegenerative diseases.

Impact
With the uncertainty brought about by the current pandemic, this case report highlights the opportunity to shift the current model of care for individuals with neurodegenerative diseases such as PD.
#GoingtotheFair: a social media listening analysis of agricultural fairs1
Authors: Mahoney Julie A , Widmar Nicole J O , Bir Courtney L 
Published: July 2020

Abstract
Agricultural fairs provide one of the last frontiers, and largest stages, for showcasing livestock agriculture to the public. However, public funding, attendance revenue, animal biosecurity, and public health concerns are all aspects worthy of conversation and increased research attention given the interaction between livestock animals and the general public in fair and festival settings. A prominent social media listening and data analytics platform was used to quantify online and social media chatter concerning agricultural fairs during a 27-mo period. A general search for online media referencing agricultural fair keywords was designed; social and online media mentions of agricultural fairs (n = 2,091,350 mentions) were further queried according to their reference to livestock, fair food, or the major agricultural product producing species of dairy and beef cattle (n = 68,900), poultry (n = 39,600), and swine (n = 31,250). Numbers of search results were found to be seasonal and Twitter was the single largest domain for all fair-related results; in contrast, the majority of livestock-related media was generated by news sources rather than from Twitter. On a weekly basis, the percentage of fair livestock mentions with species-specific reference was highly variable ranging from 0% to 86.8% for cattle, 0% to 85.7% for poultry, and 0% to 76.9% for swine. In addition to quantifying total search hits or mentions, the positivity/negativity of the search results was analyzed using natural language processing capabilities. The net sentiment quantified is the total percentage of positive posts minus the percentage of negative posts, which results in a necessarily bounded net sentiment between −100% and +100%. Overall net sentiment associated with mentions of agricultural fairs was positive; the topics garnering the highest positive sentiments were fair food and cattle (both 98% positive). Online discussion pertaining to agricultural fairs and swine was overall positive despite references to swine flu outbreaks. In conclusion, livestock and animal products had positive net sentiment over the time period studied, but there are multiple aspects of agricultural fairs worthy of further investigation and continued vigilance, including zoonotic disease risk and public perceptions of livestock industries.
Tree physiological monitoring of the 2018 larch budmoth outbreak: preference for leaf recovery and carbon storage over stem wood formation inLarix decidua
Authors: Peters Richard L , Miranda Jose Carlos , Schönbeck Leonie , Nievergelt Daniel , Fonti Marina V , Saurer Matthias , Stritih Ana , Fonti Patrick , Wermelinger Beat , von Arx Georg , Lehmann Marco M 
Published: July 2020

AbstractInsect defoliation impacts forest productivity worldwide, highlighting the relevance of plant–insect interactions. The larch budmoth (Zeiraphera griseana Hübner) is one of the most extensively studied defoliators, where numerous tree ring-based analyses on its host (Larix decidua Mill.) have aided in identifying outbreak dynamics over the past millennia. Yet, outbreaks have been widely absent after the early 1980s, and little is known about the in situ tree physiological responses and the allocation of carbon resources during and after defoliation. In summer 2018, we tracked an ongoing larch budmoth outbreak in a well-studied larch forest in the Swiss Alps. We performed biweekly monitoring on an affected and unaffected site using a unique combination of xylogenesis observations, measurements of non-structural carbohydrates, isotopic analysis of needle assimilates and ground-based and remote-sensed leaf trait observations. The budmoth induced a defoliation that lasted 40 days and could be detected by satellite observations. Soluble sugars significantly decreased in needles and stem phloem of the defoliated trees, while starch levels remained stable in the stem and root xylem compared to the control. Carbon and oxygen isotope ratios in needle assimilates indicated that neither photosynthetic assimilation rates nor stomatal conductance was different between sites before, during and after the outbreak. Defoliated trees ceased cell wall thickening 17 days earlier than unaffected trees, showing the earliest halt of ring formation recorded from 2007 untill 2013 and causing significant thinner cell walls, particularly in the latewood. No significant differences were found for cell enlargement rates and ring width. Our study revealed that an outbreak causes a downregulation of cell wall thickening first, while no starch is mobilized or leaf physiology is adjusted to compensate for the reduced carbon source due to defoliation. Our observations suggest that affected larch trees prioritize leaf recovery and carbon storage over wood biomass development.