bluuebunny/crossref_metadata_2025_split huggingface dataset:
Drug-Induced Acute Tubulointerstitial Nephritis
Authors: Rădulescu Daniela 
Published: November 2020

Abstract
Nowadays, incidence of drug-induced acute tubulointerstitial nephritis is on the rise due to increased access of the patients to a variety of both prescribed and over-the-counter drugs. Acute kidney injury and hypersensitivity manifestations are the main features of acute tubulointerstitial nephritis.
Classically considered reversible after prompt withdrawal of the offending medication, recent decades revealed potential for evolution to chronic kidney disease. This article presents the challenges in the diagnosis and treatment and also evolutive features of allergic acute tubulointerstitial nephritis induced by drugs.
Identical STEMI Pattern in Two Siblings with Different Risk Factors
Authors: Gerculy Renata , Libenciuc Camelia , Rat Nora , Kovacs Istvan , Chitu Monica , Benedek Imre , Benedek Theodora 
Published: November 2020

Abstract
Environmental factors may have an important role in the development of coronary heart disease. However, it is not clearly understood yet how the genetic factors interplay with the environmental ones in the onset of acute myocardial infarction. The early onset of coronary artery disease in cases with a positive family history suggests a certain role of genetic predisposition, but the open question remains: could environmental differences contribute to this predisposition? This case report describes similar coronary angiographic findings of two brothers who developed acute myocardial infarction in their early 40s, after being exposed to different environmental risk factors.
Left Ventricular Assist Device-Related Complications
Authors: Clement Alexandra , Anghel Larisa , Sascău Radu , Stătescu Cristian 
Published: November 2020

Abstract
Left ventricular assist device (LVAD) has emerged as a safe, durable, and revolutionary therapy for end-stage heart failure patients. Despite the appearance of newer-generation devices that have improved patient outcomes, the burden of adverse events remains significant. Although the survival rate for patients with LVAD is appreciated to be 81% at 1 year and 70% at 2 years, the incidence of adverse events is also high. Over time, both early and late postimplant complications have diminished in terms of prevalence and impact; however, complications, such as infections, bleeding, right heart failure, pump thrombosis, aortic insufficiency, or stroke, continue to represent a challenge for the practitioner. Therefore, the aim of this review is to highlight the most recent data regarding the current use of LVAD in the treatment of end-stage heart failure, with a specific focus on LVAD-related complications, in order to improve device-related outcomes. It will also revise how to mitigate the risk and how to approach specific adverse events. Withal, understanding the predisposing risk factors associated with postimplant complications, early recognition and appropriate treatment help to significantly improve the prognosis for patients with end-stage heart failure.
Myocardial Injury and Myocarditis in SARS-CoV-2 Patients
Authors: Libenciuc Camelia , Licu Răzvan-Andrei , Hodas Roxana , Chitu Monica , Benedek Imre 
Published: November 2020

Abstract
Myocarditis is one of the relatively common complications of respiratory infection with SARSCoV-2. As several patients confirmed with the new SARS-CoV-2 are known with cardiovascular disease (CVD) and data from the literature show negative prognosis and a higher risk of complications, this subgroup of subjects represents a particular situation. Therefore, an adequate understanding of the mechanisms involved in myocardial injury and interaction between COVID-19 and CVD is essential for optimal further management. Studies have proved that in COVID-19 patient myocarditis is determined via three pathological mechanisms of cardiomyocyte injury: direct viral cell entry and binding to ACE2, vasculitis-mediated injury, and systemic inflammatory response leading to pro-inflammatory cytokine discharge. Studies show that the incidence of myocarditis in patients with SARS-CoV-2 is relatively low, 4.8%, but myocardial damage occurs in more than 25% of critical cases in the form of acute fulminant myocarditis with severe hemodynamic degradation, or develops when the severity of SARS-CoV-2 infection intensifies. The mortality rate in myocarditis from COVID-19 infection ranges between 50–70%, with poorer prognosis and a higher risk of complications in CVD patients. As in all of these cases increased troponin and natriuretic peptide levels proved to be a negative prognostic factor, for risk stratification and prompt treatment, cardiac biomarkers should be evaluated in all patients with COVID-19.
Allergies in Dental Practice – Questionnaire-Based Study
Authors: Lőrincz Hajnal , Kovács Henrietta Zsófia , Kerekes-Máthé Bernadette 
Published: November 2020

Abstract

Background: Allergy is one of the most widespread diseases in this century. Allergy-causing materials used in dentistry are most frequently metals, such as nickel, cobalt, palladium, and amalgam, certain components of dental composites, denture resin materials, and even certain mouthwash components. The aim of this study was to assess dentists’ experience regarding allergies occurring in their practice among patients and among dental team members.

Material and methods: We conducted a questionnaire-based study, in which 104 dentists responded.

Results: Immediate allergic reactions were more often caused by different drugs, detergents, and anesthetics, while delayed allergic reactions were mostly caused by acrylates. Allergic reactions occurred more often among women than men, but the difference was not statistically significant (p = 0.3).

Conclusions: Our results suggest that allergies in dentistry appear mainly among adults, caused mostly by acrylates, metals, and different drugs. Immediate allergic reactions are often present, and mostly women are susceptible to allergies.
A Case of Acute Myocardial Injury – MINOCA or Myocarditis?
Authors: Libenciuc Camelia , Licu Răzvan-Andrei , Kovacs Istvan , Chitu Monica , Benedek Imre 
Published: November 2020

Abstract
Myocardial infarction with non-obstructive coronary arteries (MINOCA) has been defined as clinical presentation of an acute coronary syndrome with laboratory evidence of myocardial necrosis, but with coronary stenosis of less than 50% on coronary angiography. On the other side, myocarditis is an inflammatory response triggered by viral, bacterial, fungal, lymphocytic, eosinophilic, or autoimmune myocardial injury, which may be associated with elevated myocardial necrosis serum biomarkers. We present the case of a young male patient with acute chest pain, ST-segment elevation, and high-sensitivity troponin levels of 22,162 ng/L.
Connecting hillslope and runoff generation processes in the Ethiopian Highlands: The Ene-Chilala watershed
Authors: Addisie Meseret B. , Ayele Getaneh K. , Hailu Nigus , Langendoen Eddy J. , Tilahun Seifu A. , Schmitter Petra , Parlange J.-Yves , Steenhuis Tammo S. 
Published: November 2020

Abstract
Effective watershed planning requires an understanding of the hydrology. In the humid tropical monsoon climates and especially in volcanic highland regions such as the Ethiopian Highlands, the understanding of watershed processes is incomplete. The objective is to better understand the hydrology of the volcanic regions in the humid highlands by linking the hillslope processes with the discharge at the outlet. The Ene-Chilala watershed was selected for this study. The infiltration rate, piezometric water levels and discharge from two nested sub watersheds and at the watershed outlet were measured during a four-year period. Infiltration rates on the hillsides exceeded the rainfall intensity most of the time. The excess rain recharged a perched hillside aquifer. Water flowed through the perched aquifer as interflow to rivers and outlet. In addition, saturation excess overland flow was generated in the valley bottoms. Perched water tables heights were predicted by summing up the recharge over the travel time from the watershed divide. Travel times ranged from a few days for piezometers close to the divide to 40 days near the outlet. River discharge was simulated by adding the interflow from the upland to overland flow from the saturated valley bottom lands. Overland flow accounted only for one-fourth of the total flow. There was good agreement between predicted and observed discharge during the rain phase therefore the hillslope hydrologically processes were successfully linked with the discharge at the outlet.
An empirical model for describing the influence of water content and concentration of sulfamethoxazole (antibiotic) in soil on the total net CO2 efflux
Authors: Fér Miroslav , Kodešová Radka , Kalkušová Barbora , Klement Aleš , Nikodem Antonín 
Published: November 2020

Abstract
The aim of the study was to describe the impact of the soil water content and sulfamethoxazole, SUL, (antibiotic) concentration in soil on the net CO2 efflux. Soil samples were taken from topsoils of a Haplic Fluvisol and Haplic Chernozem. Soil samples were packed into the steel cylinders. The net CO2 efflux was measured from these soil columns after application of fresh water or SUL solution at different soil water contents. The experiments were carried out in dark at 20°C. The trends in the net CO2 efflux varied for different treatments. While initially high values for water treatment exponentially decreased in time, values for solution treatment increased during the first 250–650 minutes and then decreased. The total net CO2 effluxes measured for 20 hours related to the soil water content followed the second order polynomial functions. The maximal values were measured for the soil water content of 0.15 cm3 cm−3 (Haplic Fluvisol with water or solution, Haplic Chernozem with solution) and 0.11 cm3 cm−3 (Haplic Chernozem with water). The ratios between values measured for solution and water at the same soil water contents exponentially increased with increasing SUL concentration in soils. This proved the increasing stimulative influence of SUL on soil microbial activity.
Leonard Horner in Bonn 1831–1833, finding loess and being incorporated into Lyell’s Loess Legion
Authors: Smalley Ian 
Published: November 2020

Abstract
Leonard Horner (1785–1864) was a pioneer in the study of loess. His 1836 paper on the geology of Bonn contained detailed descriptions of loess in the Rhine valley. He identified and presented loess as an interesting material for geological study. He investigated loess in the crater of the Rodderberg with Charles Lyell in 1833. He presented the first significant paper on loess in Britain in 1833, but it was not published until 1836. With the assistance of G.A. Goldfuss and J.J. Noegerath he conducted early studies of the Siebengebirge and published the first geological map of the region, and the first picture of loess, at Rhondorf by the Drachenfels. He became the eleventh person to be included in the list of loess scholars which Charles Lyell published in volume 3 of the Principles of Geology. These were Leonhard, Bronn, Boue, Voltz, Steininger, Merian, Rozet, Hibbert in 1833, Noeggerath, von Meyer in 1835, Horner in 1837. Horner arrived after the publication of his studies on the loess at Bonn in 1836.
Sum of the spaces on ordered setting
Authors: Al-shami T. M. 
Published: November 2020

Abstract
One of the divergences between topology and ordered topology is that some topological concepts such as separation axioms and continuous maps are defined using open neighborhoods or neighborhoods without any difference, however, they are distinct on the ordered topology according to the neighborhoods: Are they open neighborhoods or not? In this paper, we present the concept of sum of the ordered spaces using pairwise disjoint topological ordered spaces and study main properties. Then, we introduce the properties of ordered additive, finitely ordered additive and countably ordered additive which associate topological ordered spaces with their sum. We prove that the properties of being T

i
-ordered and strong T

i
-ordered spaces are ordered additive, however, the properties of monotonically compact and ordered compact spaces are finitely ordered additive. Also, we define a mapping between two sums of the ordered spaces using mappings between the ordered spaces and deduce some results related to some types of continuity and homeomorphism. We complete this work by determining the conditions under which a topological ordered space is sum of the ordered spaces.
Exploration of optoelectronic, nonlinear and charge transport properties of hydroquinoline derivatives by DFT approach
Authors: Irfan Ahmad , Al-Sehemi Abdullah G. , Chaudhry Aijaz Rasool , Muhammad Shabbir , Jin Ruifa 
Published: November 2020

Abstract
Present investigation deals with an in depth study of three compounds including 4-(4-chlorophenyl)-8-methyl-2-oxo- 1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile (1), 4-(4-bromophenyl)-8-methyl-2-oxo-1,2,3,4,4a,5,6,7-octahydroquinoline-3- carbonitrile (2) and 8-methyl-2-oxo-4-(thiophen-2-yl)-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile (3) with respect to their structural, electronic, optical and charge transport properties. The ground and excited states geometries were optimized by density functional theory (DFT) and time dependent DFT, respectively. To rationalize the adopted methodology, the calculated geometrical parameters at ground state were compared with the experimental crystal structures. Several quantum chemical insights including the analysis of frontier molecular orbitals (FMOs), total/partial density of states (T/PDOS), molecular electrostatic potentials (MEP), local and global reactivity descriptors revealed that the studied compounds would be efficient multifunctional materials. The absorption wavelengths as well as their major transitions were thoroughly studied at TD-B3LYP/6-31G** level of theory. The smaller hole reorganization energies indicate that all these compounds might show better hole transport tendency. The anionic geometry relaxation of compound 2 is larger than the cationic form which leads to higher electron reorganization energy revealing the reduction of electron charge transport as compared to the hole.
Comparison of dose distributions in target areas and organs at risk in conformal and VMAT techniques and dose verifications with the use of thermoluminescence dosimetry
Authors: Paluch-Ferszt Monika , Kozłowska Beata , Dybek Marcin 
Published: November 2020

Abstract
The aim of the present study is to compare dose distributions and their verification in target areas and organs at risk (OAR) in conformal and volumetric modulated arc therapy (VMAT) techniques. Proper verification procedures allow the removal of the major sources of errors, such as incorrect application of a planning system, its insufficient or cursory commissioning, as well as an erroneous interpretation of the obtained results. Three target areas (head and neck, chest, and pelvic) were selected and the treatment was delivered based on plans made using collapsed cone convolution and Monte Carlo algorithms with 6-MV photon beams, adopting conformal and VMAT techniques, respectively. All the plans were prepared for the anthropomorphic phantom. Dose measurements were performed with TL detectors made of LiF phosphor doped with magnesium and titanium (LiF:Mg,Ti). This paper presents the results of TL measurements and calculated doses, as well as their deviations from the treatment planning system (TPS) in the three planned target areas. It was established that the algorithms subject to analysis differ, particularly in dose calculations for highly inhomogeneous regions (OAR). Aside from the need to achieve the dose intended for the tumour, the choice of irradiation technique in teleradiotherapy should be dictated by the degree of exposure to individual critical organs during irradiation. While nothing deviated beyond the bounds of what is acceptable by international regulatory bodies in plans from TPS, clinically one must be more cautious with the OAR areas.
Efficient reading of thermoluminescent dosimeter signals using semiconductor detectors
Authors: Sobotka Piotr , Kliś Bartłomiej , Baranowska Zuzanna , Wołoszczuk Katarzyna , Rutkowska Katarzyna , Woliński Tomasz 
Published: November 2020

Abstract
The aim of this experimental work was to examine whether semiconductor photodetectors may be applied for the efficient reading of thermoluminescent dosimeter (TLD) signals. For this purpose, a series of experiments have been performed at the Department of Physics, Warsaw University of Technology, in cooperation with the Central Laboratory for Radiological Protection (CLOR). Specifically, the measurement system proposed here has been designed to detect a signal from TLDs that use a semiconductor detector operating in conditions analogous to those met when using commercial devices equipped with a classic photomultiplier. For the experimental tests, the TLDs were irradiated with a beam of 137Cs radiation in the accredited Laboratory for Calibration of Dosimetric and Radon Instruments. Eventually, a comparison of the results obtained with a semiconductor detector (ID120) and a commercial TLD reader with a photomultiplier tube (RADOS) were made.
The Influence of the Flushing Method on the Stable Oxygen Content in the Scr1 Crabe Breathing Loop in the Decompression Phase
Authors: Woźniak Arkadiusz 
Published: November 2020

Abstract
Maintaining a stable oxygen content in the breathing loop of the diving apparatus with a semi-closed respiratory circuit is essential for the safety of underwater mine clearance operations. This article discusses the influence of modified methods of flushing the breathing apparatus on the quality of the breathing loop ventilation process. The problem of flushing an apparatus is presented in light of the Polish Naval Academy’s change from statistical to deterministic decompression schedules, based on the model of apparatus ventilation, oxygen toxicity hazard and decompression. The examination and determination utilising the required accuracy of the method used for flushing the breathing loop of the device allowed to assess the stable oxygen content during the decompression phase. The assumptions were verified based on a system for measuring oxygen content in the breathing loop.
Compensatory Paraoxonase and Arylesterase Levels in Hyperbaric Oxygen Treatment of Sudden Sensorineural Hearing Loss
Authors: Eren Esin , Yilmaz Necat , Yildirim Furkan , Giray Ozlem 
Published: November 2020

Abstract

Objective: Paraoxonase1 (PON1) and Arylesterase (ARE) levels are associated with reduced risk of atherosclerosis. The functional status of high density lipoprotein (HDL) is closely related to the PON1/ARE enzyme activity. Functional changes in treatment of sudden sensorineural hearing loss (SSNHL) may be achieved by post-translational modification of lipid metabolism induced by hyperbaric oxygen therapy (HBOT).

Methods: Men patients with SSNHL who met the research criteria were included in the study. HBOT was performed on average 30 sessions. Laboratory measurements were made at the beginning and end of HBOT for the same patients. Serum levels of PON1/ARE and routine lipid laboratory parameters were measured to determine possible changes in SSNHL after HBOT.

Results: In this study, a reducing effect on PON1 enzyme amount of long-term HBOT was detected. The serum PON1 amount of patients with SSNHL was 19.7 ± 2.7 ng / mL (mean ± SD) before HBOT, and the serum PON1 decreased to 17.0 ± 2.1 ng / mL (mean ± SD) after 30 sessions of HBOT. This decrease in PON1 levels was statistically significant (p =0.035). There was also a statistically significant decrease in the enzyme activity of ARE in the SSNHL patients (p=0.024).

Conclusion: This preliminary study showed a significant decrease in serum PON1/ARE enzyme content in SSNLH patients with HBOT. In fact, it can be assumed that HBOT has no adverse effect on HDL functionality. However, the decrease in PON1 level by HBOT with 30 or more sessions may be important for the antioxidant function of HDL.It may possibly cause post-translational changes in antioxidant defense mechanisms due to increased oxidative stress with HBOT. In conclusion, larger clinical studies are needed to determine the possible effects of HBOT on HDL-related PON1/ARE functionality in SSNHL.
“Confused Anarchy and the late civil broils”: The Politics of Genre in Milton’s Histories
Authors: Dasgupta Sukanya 
Published: November 2020

Abstract
The writing of history was seminal to Milton’s conception of himself as a humanist and is a key to our understanding of his literary career. Yet, Milton’s Brief History of Moscovia and The History of Britain occupy a unique position in the way in which they are poised between the humanist notion of history as counsel and history as an assertion of “republican” values. However, situating Milton in a climate of republicanism has othen been problematic and challenging. Like writers of humanist historical narratives, Milton’s primary aim was to guide the English people in their current political crisis by making the past an analogue of the present. I wish to contend that he approaches his intention generically: by a manipulative use of the genres of history and chorography, Milton is able to straddle the earlier notion of history with the later notions of “republicanism” that permeated the political climate of England in the aftermath of the Civil War. In an inversion of Shklovsky’s notion of “form shaping content”, Milton’s reliance on genre as a vehicle for articulating his political and ideological stance, ultimately results in content shaping form.
When “We Believe that ...”: The Role of Collective “we” in the Dialogic Negotiation in Hard News Discourse
Authors: Nádraská Zuzana 
Published: November 2020

Abstract
The present paper examines the occurrence of collective self expressed by the first person plural “we” in British broadsheet hard news reports. Given that “we” typically embraces “I” and the “non-I”, and is viewed in contradistinction to “others”, it is subjective and dialogic (inter-subjective) in nature (Baumgarten et al.; Benveniste). This study, grounded in Systemic Functional Linguistics and the theory of engagement, examines the coupling, i.e., co-occurrence, of one dialogic signal “we” with other dialogic meanings (entertain, proclaim and disclaim) used for the dialogic negotiation of content and writer-reader engagement (Martin, “Beyond Exchange”; Martin and White). Couplings are interpreted from the point of view of the overall rhetorical strategy they are put to, referred to as syndromes of meaning (Zappavigna et al., “Syndromes”; Zappavigna et al., “The Coupling”). The rhetorical functions of syndromes reflect the basic dialogic meanings of the examined engagement categories such as a tentative suggestion of an opinion (entertain), a strong statement of an opinion (proclaim) and a rejection of a dispreferred opinion (disclaim). Finer variations within the individual rhetorical strategies are related to the difference in the source of dialogic positioning (an individual versus collective voice) and the referential scope of the pronoun (a precisely defined reference versus reference with a more general and diffused scope).