bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANTIBIOTICOTERAPIA COM INIBIDORES β-LACTÂMICOS PARA RESSENSIBILIZAÇÃO DE BACTÉRIAS MULTIRRESISTENTES
Authors: Barbosa Kledson Lopes , Araújo Fábio Ferreira de , Lins Dênis Fagner Souza 
Published: December 2020

O uso indiscriminado de antibióticos de um modo geral proporcionou o desenvolvimento de várias bactérias multirresistentes, as quais são responsáveis por infecções sistêmicas de grande importância clínica. O objetivo deste estudo foi descrever de forma narrativa a resistência antibiótica aos β-lactâmicos e sua administração combinada com outros fármacos visando a ressensibilização bacteriana de cepas multirresistentes. Trata-se de um estudo qualitativo de revisão narrativa, constituída por análise da literatura com busca de dados publicados na base de dados ScienceDirect sobre o tema “uso de inibidores β-lactâmicos para o tratamento de infecções causadas por bactérias multirresistentes”. Este estudo mostrou que há possibilidades de tratamento das infecções bacterianas causadas por cepas multirresistentes por meio de antibioticoterapia de inibidores β-lactâmicos. As infecções bacterianas multirresistentes continuam sendo um grande desafio para medicina, uma vez que existem enzimas que conferem resistência bacteriana contra todos os antibióticos. Mesmo que atualmente exista inibidores de β-lactamases disponíveis e com atividade antimicrobiana, é necessário que o esforço pela busca de novos antibióticos seja contínuo para o controle de bactérias multirresistentes.
COMPARAÇÃO DOS PARÂMETROS DE QUALIDADE DE COMPRIMIDOS DE ATENOLOL SIMILARES E GENÉRICOS EM RELAÇÃO AO MEDICAMENTO REFERÊNCIA
Authors: Teodoro Emilly Isabelli dos Santos , Silva Thalita Prates da , Paula Mariana Nascimento de , Mello João Carlos Palazzo de , Lopes-Ortiz Mariana Aparecida , Medeiros Araújo Daniela Cristina de 
Published: December 2020

A equivalência farmacêutica entre dois medicamentos corresponde à comprovação de que ambos contêm o mesmo fármaco; isso é; mesmo sal ou éster da mesma molécula terapeuticamente ativa; mesma concentração; forma farmacêutica e via de administração; podendo ou não conter excipientes idênticos. Os testes realizados para análise comparativa de qualidade incluem ensaios físico-químicos e; quando aplicáveis; microbiológicos e biológicos. Neste trabalho foram avaliados os parâmetros de qualidade de duas marcas de medicamento genérico (denominadas D e E) e duas marcas de similar (B e C) em relação ao medicamento referência (A) de atenolol 50 mg. Foram realizados os testes de peso médio; friabilidade; desintegração e doseamento. Além disso; o controle microbiológico das amostras foi realizado por meio da contagem do número total de micro-organismos mesofílicos. O resultado foi que não ocorreu crescimento de colônias. Todas as amostras testadas cumpriram os requisitos dos testes realizados; de acordo com os parâmetros descritos na Farmacopeia Brasileira 6ª edição.
Representatividade de Paulo Freire no ensino de CTS brasileiro: olhares por meio da análise de redes sociais
Authors: Dionysio Renata Barbosa , Chrispino Alvaro , Carvalho Aline Paixão Miranda , Menezes Rosilene Ferreira de Almeida , Xavier Gisele Pereira de Oliveira 
Published: December 2020

Este trabalho buscou estabelecer um primeiro panorama dos pressupostos Freireanos na produção acadêmica do ensino Ciência Tecnologia e Sociedade, CTS, no Brasil, por meio da análise das principais palavras-chave e referenciais teóricos mais recorrentes pelos pesquisadores da área. Os treze artigos analisados na pesquisa foram retirados no banco de dados do Grupo CTS e Educação do CEFET/RJ, que reúne 244 artigos sobre CTS, de 1996 a 2016, em 31 periódicos. O critério de seleção foi encontrar no título, resumo ou palavras-chave dos artigos, termos relacionados à pedagogia freireana. Num primeiro momento, investiu-se na análise de Rede Social, por meio das palavras-chaves e autores citados. Posteriormente, foi realizada uma leitura analítica nos artigos com objetivo de identificar como os saberes relacionados à abordagem desde Freire foram relacionados com o enfoque CTS. A discussão realizada no presente trabalho pode auxiliar no entendimento de como os principais campos teóricos de Paulo Freire são representados na abordagem CTS. Os resultados obtidos apresentaram evidências que levam à necessidade de análises teóricas mais profundas, mas mostram que as inter-relações entre Freire e CTS se fazem de maneira superficial e sem aprofundamento teórico.
Adverse Outcome in a Near Term, High-Risk Twin Pregnancy Complicated by COVID-19: A case report
Authors: Sarastry Razmaeda , Layarta Crismanto , Aladini Ussisti , Hafiz Alini , Pramono Besari Adi 
Published: December 2020

Background: COVID-19 affecting the outcome of pregnancy is still under investigation. Here we report a case of primigravida with monochorionic diamniotic twin pregnancy with superimposed preeclampsia who develop symptoms of COVID-19 infection on her near term pregnancy and was confirmed later on as COVID-19 positive after cesarean section. The pregnancy was terminated abdominally due to the intrauterine fetal demise of both twins using COVID-19 standard equipment.Case Presentation: A 29-year-old female, gravida 1, para 0 presented with a twin pregnancy at the gestational age of 36 weeks was referred to our emergency department for further management of intrauterine fetal death of both twins. Six days before admitted to our emergency department, she has been experienced a remittent fever which followed by a mild cough. Four days before admission, she complained of decrease movement of the babies. She went to the Secondary Hospital to check her pregnancy and both fetal heart rates were not found. The patient is obese (BMI 49.2 kg/m2) and had prior uncontrolled hypertension but no other medical history, including epilepsy, allergies, asthma, heart disease as well as Diabetes Mellitus.Conclusion: A research about placental pathology in pregnancy with confirmed case of COVID-19 infection showed no pathognomonic feature in the histopathologic examination but mostly, there were maternal vascular malperfusion (decidual arteriopathy in particular) and intervillous thrombi. In the end, a further examination is suggested to evaluate the course and causal factors pertaining to this case.
Estimation levels of prostate-specific antigen, interleukin-8, oxidative stress and some inflammatory markers in sera of benign prostatic hyperplasia patients who have smoking habits as a risk factor
Authors: Al-Barzinj Ruqaya Mohammed Ghareeb Taher 
Published: December 2020

Benign prostatic hyperplasia (BPH) is a common multifactorial inflammatory disease of older men, defined by increased growth of prostate epithelial and stromal cells. Elevation serum levels of Interleukin-8 (IL-8), oxidative stress and inflammatory markers represent predictive surrogate markers of the disease progression in smoker BPH patients. A total of 86 BPH patients and 54 control subjects were admitted to the urology unit, Rizgary Teaching Hospital in Erbil City, Iraq between January and June 2020. Sera levels of prostate-specific antigen(PSA), IL-8, malondialdehyde (MDA), high sensitive C-reactive protein (hs-CRP), testosterone and some biomarkers concentrations were measured in the patients according to instructions of manufacturers. Patients and controls were categorized into groups according to smoking status (smokers and non-smokers). The sera levels of PSA, IL-8 and inflammatory markers like oxidative stress(MDA), hs-CRP and testosterone in every smoker subgroup (BPH patients and control) increased compared to the same non-smoker subgroups and significantly increased compared with non-smoker control (p<0.05). PSA demonstrated a significant positive correlation with the following terms, IL-8, MDA, hs-CRP, testosterone and low-density lipid (LDL)(p<0.05) and, insignificant negative correlation with high-density lipoprotein(HDL), (p>0.05). The current study demonstrated mounting evidence to support the role of smoking in the pathophysiology of BPH through elevation levels of inflammatory and oxidative stress biomarkers in sera of BPH patients.
Representaciones discursivas de lo indígena en Costa Rica: un análisis a través de la red social Facebook
Authors: González Campos Guillermo 
Published: December 2020

Introducción
Este artículo lleva a cabo una discusión crítica de los principales núcleos temáticos que gobiernan la producción del sentido en mensajes generados por la población costarricense no indígena en la red social Facebook con respecto a los pueblos indígenas del país.
Objetivo
El objetivo es identificar y analizar los discursos dominantes que, en la actualidad, gobiernan lo dicho sobre la población indígena en Costa Rica.
Método
Para tal efecto, y por medio de las técnicas propias de Corpus-assisted discourse studies, se recopilaron y analizaron comentarios hechos por personas a noticias que tratan asuntos indígenas.
Resultados
El análisis revela que el discurso sobre lo indígena en Costa Rica está determinado por cuatro núcleos de generación del sentido que se consideran perjudiciales para la representación social de este tipo de poblaciones.
Conclusión
Puede concluirse que, en efecto, hay una integración a nivel del discurso de lo indígena dentro del imaginario de identidad costarricense. Pero esta imagen de lo indígena es la asimilación de un discurso creado desde la alteridad y, por lo tanto, guarda las herencias simbólicas de la ideología colonizadora que la creó.
Reconocimiento y racionalidad en Ética y diálogo, de Albrecht Wellmer
Authors: Abril Francisco Manuel 
Published: December 2020

Introducción
La temática del presente artículo refiere al vínculo que establece Albrecht Wellmer en su libro Ética y diálogo (1986), entre reconocimiento y racionalidad o facultad de juzgar. A modo de introducción, consideramos que la caracterización hecha por el autor con respecto al vínculo entre estos dos conceptos es de gran importancia ya que, una de las dificultades más significativas de la teoría crítica contemporánea, no se ha podido erigir –o por lo menos no se ha hecho de manera satisfactoria– un puente argumentativo entre la noción de racionalidad comunicativa (Habermas) y la de reconocimiento (Honneth).
Objetivo
Nuestro objetivo principal es precisar cómo entiende Wellmer el reconocimiento y cuál es la relación que establece entre este y la facultad de juzgar.
Método
Para responder a la pregunta, expondremos de forma sucinta, en la primera parte del artículo, algunas de las tesis centrales que recorren el libro aludido. Esto nos permitirá aproximarnos al punto nodal de nuestra exposición, en el cual explicaremos, utilizando la metodología de la reconstrucción conceptual, las distintas acepciones del concepto de reconocimiento y sus vínculos con la facultad de juzgar.
Resultados y conclusión
Si bien los resultados de la exposición en este punto no son definitorios, llegamos a la conclusión de que habilitan una línea prometedora para futuras investigaciones.
Raquel's Shadow: The Representation of the Holocaust in Spanish Cultural Expression<p>In collaboration with<i> Letras Peninsulares</i> 22.2 (2010)<p>Cover art courtesy of <a href="http://www.nopasaran36.org/guerra_civil/espana.php?79/Los-Campos&lang=es">Los Campos</a>
Authors: Ercelawn Ann 
Published: December 2020

In collaboration with Letras peninsulares 22.1 (2010)
Cover art courtesy ofCampos
Towards Designing a Validated Framework for Improved Clinical Legal Education: Empirical Research on Student and Alumni Feedback
Authors: Van der Merwe Stephan 
Published: December 2020

The pedagogical advantages of employing a Clinical Legal Education (“CLE”) teaching and learning strategy have been acclaimed in literature for almost a century and it continues to be ideally suited to cater to modern education expectations. As an agent for social change, CLE offers law students an effective gateway to participate in, and be influenced by, fundamental social justice problems while it also improves access to justice for the indigent. Though the clinical literature is replete on expected benefits for clinical law students, very little (if any) verifiable empirical research, independently sourced and evaluated, has been published to assess the veracity of these claims in support of CLE. After receiving a funding grant from the University of Stellenbosch Fund for Innovation and Research into Learning and Teaching, the University of Stellenbosch Law Clinic appointed an independent, external agency to conduct empirical research through an extensive measure and evaluation exercise. The aim of the project was to source, document and analyse robust empirical research data about the Faculty of Law’s CLE module, Practical Legal Training 471. The project involved the sourcing and collation of formal student evaluation feedback reports spanning a period of nine years. Additional alumni and current student data were gathered either by online questionnaire or by telephonic interview. The research was aimed at eliciting quantitative as well as qualitative responses.
The purpose of this article is to describe the applicable methodology and aims of the research project, to unpack and discuss the resulting empirical data, and to draw certain conclusions based on the findings of this research about CLE’s impact on law students’ experience specifically relating to their practice-readiness and social justice sensitivities. It is suggested that this research will prove both interesting and useful to law teachers involved in relevant programmes at other higher education institutions. The data and evidence detailed herein will assist them to conduct their research and to make substantiated recommendations for the development of CLE programs on a broader national and international level. This research will also add to the body of knowledge on students and student learning and allow for recommendations regarding the creation of a broader implementation framework for improved CLE.
EDITORIAL
Authors: Amorim Ricardo José Rocha , Pinheiro Francisco Marton Gleuson , Frazão Maria de Fátima Araújo 
Published: December 2020

Nesta edição, constam oito trabalhos com diversidade de temáticas. Os dois primeiros artigos tratam da perspectiva bibliométrica: um sobre incentivos fiscais no contexto da literatura internacional; e, o outro, sobre a produção acadêmica com enfoque na gestão e no gerenciamento de riscos. Já, o terceiro estudo, discorre sobre a avaliação da produção científica de Programas de Pós-Graduação em Contabilidade com base na mudança de critérios da Capes.
Por sua vez, as determinantes da estrutura de capital do setor bancário são analisadas no quarto estudo. O quinto artigo, trata das micro finanças para os pequenos empreendimentos, ao passo que o sexto, aborda os possíveis efeitos advindos do vazamento da delação premiada de um importante executivo da JBS S.A. sobre os retornos do mercado acionário brasileiro. Por fim, os dois últimos trabalhos desta edição tratam de casos para ensino envolvendo a tomada de decisão na área de tecnologia da informação.
Com isso, resta-nos agradecer o apoio de todos os envolvidos no processo de submissão, avaliação e editoração do periódico. Obrigado!
A technique of hemodialysis in patients with extracorporeal membrane oxygenation
Authors: SERT Dogan Emre , KARAHAN Mehmet , KOCABEYOĞLU Sinan Sabit , KERVAN Ümit 
Published: December 2020

Aim: We aimed to evaluate the safety and feasibility of hemodialysis (HD) by using a screw compressor clamp on extracorporeal membrane oxygenation (ECMO) lines without placing a central venous catheter.
Material and Methods: From May 2013 to September 2017, 43 adult patients with ECMO that required renal replacement treatment with HD were included.The inflow of the dialysis machine was connected to the outlet of the oxygenator, and the outflow was connected to the venous line using two 3-way taps. The tool that was used on the outflow circuit to perform HD is a clamp on a screw, allowing us to squeeze and de-squeeze to set the optimal line pressure. Creatinine, blood urea nitrogen, pH, base deficit, lactate dehydrogenase (LDH) values were evaluated, and compared pre/post-HD. Rate and duration of dialysis were also analyzed.
Results: HD was successfully performed in all patients with this technique without additional morbidity and mortality. No related complications due to HD were observed. Blood urea nitrogen, creatinine, pH, base deficit values were decreased to the desired levels after dialysis (p
Study on the Impact of Infectious Diseases on the Safety of Rural Areas and its Optimal Governance—A Case Study of Hoh-hot-Baotou-Rrdos-Yulin Economic Zone
Authors: Zhang Xuan 
Published: December 2020

<p>In recent years, safety has been gradually put into the national key construction list, and the work of rural safety is also in full swing. But with the sudden emergence of events, rural security has shown a huge vulnerability. By contacting the outbreak area of Hubei rural construction of safety management, the purpose of this article is to found that infectious diseases during the period of economic, political, social, ideological, ecological impact safety problems and put forward the optimization scheme, called for of the construction of the rural security key to return, to improve the safety of the sudden outbreak response capacity.</p>
Does Strategic Leadership Affect Financial Performance? (A Study of Selected Firms of Textile Industry in Pakistan)
Authors: Rasool Nosheen , Hussain Muhammad Mubashir 
Published: December 2020

Performance is largely related to management decisions. WithinÂ Â the hierarchy of a company, maximum power is vested in the strategic leadership. Thus, it is the strategic leadership that is primarily responsible for the efficient working of the company. By adopting different types of leadership behaviours, such as charismatic, considerate or transactional, the strategic leader motivates his subordinates for efficient working. This affects the overallÂ performance of a company. The financial performance has been measured through Sales, Net Profit Margin, Earnings per Share, Return on Equity and Return on Asset. The results support the theory that charismatic trait of leadership has the most significant impact on the financial performance of a company. The other two types of leadership behaviours, considered in this study, have no significant impact on the financial performance.
Does Dodd Frank Act Affect Macroeconomic Variables?
Authors: Kalbasi Anaraki Nahid 
Published: December 2020

The introduction of Dodd Frank Act has induced lots of controversy among economists on its macroeconomic outcomes; though some see it is a necessary piece of legislation, which can avoid future financial crisis, many think it is detrimental to private investment and employment. To see how the Act affect real macroeconomic variables such as GDP growth, investment, and unemployment rate, this study implements econometric models with time series data over the period of 1990-2015 to estimate how financial regulations in general and Dodd Frank Act in particular affects the above-mentioned variables. The results of this study suggest that the Act has a negative significant impact on GDP growth, private investment, and unemployment rate. Â Â Â
Economics of Health Human Capital in Jammu and Kashmir
Authors: Khan Javid Ahmad , Agrawal Dr Sarita 
Published: December 2020

In this paper an attempt has been made to estimate and analysis the growth and performance of the human capital in Jammu and Kashmir. Given different components of the human capital only health human capital is estimated and analyzed. The health human capital as a proxy variable for human capital is analyzed for inputs and outputs. The proxy variables included total expenditure on health, health expenditure as percentage share of total expenditure and GSDP, quality variables like institutional availability and man power, medical attention received, life expectancy average, mortality rates by sex and residence, birth and death rates, natural growth rates, child mortality, total fertility. Both econometrics and non-econometrics methods were used for estimation. The study concludes that health human capital has increased in the state over time but pace and acceleration was low. Following the findings the study recommends the attention of government to increase the standard of health in Jammu and Kashmir. Substantial amount of government budgetary allocation should be directed towards the health sector and minimization of gap of urban rural access to health care is strongly recommended by increasing infrastructure. Â Last but not least the availability of institutions and increase in the man power engaged in health sector must be increased.
Mini Milk Revolution: A Case Of Youth Leadership For Village Economy
Authors: Channaveer R.M. 
Published: December 2020

Dr. Kurien the father of white revolution in India is not known in this village, but his mission is getting white here.Â Yelladgundi a remote village in Karnataka is getting white face-lift due to a transformative youth initiative.Â A handful of youths are striving for the last over two years to transform their village through self-help and milk diary activities. Village is flooded with milky animals, youths are no more wasting time as earlier, women's purse is filled with bounty of rupees, shy educated youths are grazing cattle and working in fields, and lakh of rupee revenue is drawn to the village. And so, the fields are filled with abode of happiness, as youth are working in the fields, once neglected considering it a low dignity work.Â Responsible youths are now affectionately pushing the elderly engaged in fields to homes for needed rest with a feeling of great sigh.
Organic Farming For Sustainable Agriculture: A Comparative Analysis Of Organic Versus Conventional Rice And Cotton
Authors: Sujatha R.V. , Suhasini K. , Prasad Y. Eswara 
Published: December 2020

Organic farming is not new to Indian farming community.Â Several forms of organic farming are being successfully practiced in diverse climate, particularly in rain-fed, tribal, mountains and hill areas of the country. Among all farming systems, organic farming is gaining wide attention among farmers, entrepreneurs, policy makers and agricultural scientists for varied reasons such asÂ it minimizes the dependence on chemical inputs (fertilizers; pesticides; herbicides and other agro-chemicals) thus safeguards/ improves quality of resources, and environment. It is labour intensive and provides an opportunity to increase rural employment and achieve long term improvements in the quality of resource base.Organic farming has received considerable attention in India in the recent past. In India, the per cent area under organic farming is only 0.03 per cent of the total area under agriculture when compared to Austria (11.30%), Switzerland (9.70%) and Italy (7.94%) according to SOEL Survey, February 2003. Some of the major organically produced agricultural crops in India include crops like plantation, spices, pulses, fruits, vegetables and oil seeds etc
South â€“East Asian Crisis- An Important Lesson for the Global Economy
Authors: Jain Prerna , Jain Pragati 
Published: December 2020

Crises are an intrinsic feature of the marketâ€“oriented credit and financial system. Business cycles showing periods of boom and bust will continue to occur, only the intensity shall matter. An unprecedented crisis that erupted in five Asian economies: Indonesia, Malaysia, the Phillipines, the Republic of Korea and Thailand, in mid 1997-1998 raised concern about the stability of the â€œGlobal Financial Architecture.â€Â The clear evidence emerged of a rapid and unsustainable buildup of investment in fixed assets financed by excessive borrowing. This investment-spending spree resulted in poor profitability, reflected in low and declining returns on equity and on capital employed. The severity of the crisis in the Asian region was so great that some other countries in the world â€“ Brazil and Russia, in particular also got affected by the contagion.