bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnetic amino‐functionalized hollow silica‐titania microsphere as an efficient sorbent for extraction of pesticides in green and roasted coffee beans
Authors: Asadi Marjan , Sereshti Hassan 
Published: March 2020

AbstractThis study describes the synthesis and application of a magnetic amino‐functionalized hollow silica‐titania microsphere as a new sorbent for magnetic dispersive micro‐solid phase extraction of selected pesticides in coffee bean samples. The sorbent was fully characterized by Fourier‐transform infrared spectroscopy, field emission scanning electron microscopy, transition electron microscopy, energy‐dispersive X‐ray spectroscopy, and vibrating sample magnetometry techniques. Significant extraction parameters affecting the proposed method, such as extraction time, sorbent amount, sample solution pH, salt amount, and desorption conditions (desorption solvent and time) were investigated and optimized. All the figures of merits were validated in coffee bean samples under the matrix‐matched calibration method. Linear dynamic ranges were 5–250 µg/kg with the determination coefficients (R2) > 0.9980. The limits of detection for the pesticides of chlorpyrifos, malathion, hexaconazole, and atrazine were 1.42, 1.43, 1.35, and 1.33 µg/kg, respectively. Finally, the method was successfully applied for the determination of the pesticides in green and roasted coffee bean samples, and the obtained recoveries were in the range of 74–113% for spiked samples. The prepared sorbent could be used for the magnetic dispersive micro‐solid phase extraction of pesticides in the plant‐derived food matrix.
Fetal Ultrasound and Magnetic Resonance Imaging Findings in Suspected Septo‐Optic Dysplasia
Authors: Maduram Amy , Farid Nikdokht , Rakow‐Penner Rebecca , Ghassemi Neda , Khanna Paritosh C. , Robbins Shira L. , Hull Andrew , Gold Jeffrey , Pretorius Dolores H. 
Published: March 2020

ObjectivesTo investigate prenatal imaging findings supporting a diagnosis of suspected septo‐optic dysplasia (SOD) by fetal ultrasound (US), magnetic resonance imaging (MRI), or both.MethodsA retrospective review identified 11 patients with SOD: 9 had a clinical diagnosis of SOD postnatally, and 2 were terminated on the basis of suspicious prenatal imaging. Prenatal and neonatal imaging of the cavum septi pellucidi (CSP), frontal horns (FHs), and lateral ventricles was evaluated.ResultsThe appearance of the CSP varied on US and MRI. Complete (“fused”) FHs or partial absence of the CSP was reported in 6 of 11 patients by fetal US and 7 of 8 patients by fetal MRI. The diagnosis of SOD was prospectively suspected prenatally in 6 of 11 and in an additional 5 of 11 cases retrospectively. Fetal MRI incorrectly initially reported normal morphologic abnormalities for 2 cases with partial absence of the CSP, whereas US accurately identified the morphologic abnormalities in 1 of these cases before MRI. Imaging features were first suggested at anatomic US (4 patients) and follow‐up prenatal US (2 patients). Neonatal imaging was concordant in all 9 live births: 5 completely absent CSP, 3 partially absent CSP, and 1 completely present CSP. Clinical manifestations included optic nerve hypoplasia (9 of 9), panhypopituitarism (5 of 9), and neurodevelopmental delays.ConclusionsPrimary imaging features of SOD are “continuous” FHs with complete or partial absence of the CSP. Septo‐optic dysplasia can be suspected in utero and can appear isolated but has substantial associated central nervous system anomalies identified on fetal MRI or after birth. Partial absence of the CSP can be a prenatal sign of suspected SOD, although fetal MRI lacked the spatial resolution to identify it accurately in all cases.
Primary culture of aspiration residual specimens improves the diagnostic accuracy between hepatocellular carcinoma and benign nodules
Authors: Lin Zu‐Yau , Wang Jing‐Houng , Yeh Ming‐Lun , Huang Ching‐I , Kee Kwong‐Ming , Yen Yi‐Hao , Chen Shinn‐Cherng , Huang Chung‐Feng , Huang Jee‐Fu , Dai Chia‐Yen , Yu Ming‐Lung , Chuang Wan‐Long 
Published: March 2020

AbstractResults of fine‐needle aspiration of hepatic nodules may be equivocal to confuse clinical judgment. The utility of primary culture of aspiration residual specimens to improve the accuracy in differential diagnosis between hepatocellular carcinoma and benign lesions was investigated. A total of 337 patients (hepatocellular carcinoma proven by aspiration 277, by other modalities 35, benign nodules 25) were included. The growth patterns of cancer cells at the 14th day of primary culture from aspiration proven hepatocellular carcinoma patients were applied as criteria for analysis. Hepatocellular carcinoma proven by aspiration showed higher incidence of outgrowth of cancer cells than those not proven by aspiration or the incidence of outgrowth of hepatocyte antigen positive cells in benign lesions (all P < .02). To differentiate hepatocellular carcinoma from benign nodules measuring ≤2 cm, growth patterns as item showed similar sensitivity and accuracy to aspiration results. The negative predictive values for the above two items in differential diagnosis were all below 45% in nodules measuring either ≤ or >2 cm. Using at least one positive result of growth patterns or aspiration as item for differential diagnosis increased the sensitivity, negative predictive value and accuracy, but little decreased the specificity and positive predictive value as compared with aspiration results alone in nodules measuring either ≤ or >2 cm. In conclusion, the growth patterns at the 14th day of primary culture can be applied for dynamic interpretation of the specimens to improve the diagnostic accuracy of fine‐needle aspiration between hepatocellular carcinoma and benign lesions.
Ultranarrow Linewidth Photonic‐Atomic Laser
Authors: Zhang Wei , Stern Liron , Carlson David , Bopp Douglas , Newman Zachary , Kang Songbai , Kitching John , Papp Scott B. 
Published: March 2020

AbstractLasers with high spectral purity can enable a diverse application space, including precision spectroscopy, coherent high‐speed communications, physical sensing, and manipulation of quantum systems. Already, meticulous design and construction of bench Fabry–Perot cavities has made possible dramatic achievements in active laser‐linewidth reduction, predominantly for optical‐atomic clocks. Yet, there is increasing demand for miniaturized laser systems operating with high performance in ambient environments. Here, a compact and robust photonic‐atomic laser comprising a 2.5 centimeter long, 20 000 finesse, monolithic Fabry–Perot cavity integrated with a micromachined rubidium vapor cell is presented. By leveraging the short‐time frequency stability of the cavity and the long‐time frequency stability of atoms, an ultranarrow‐linewidth laser that enables integration for extended measurements is realized. Specifically, the laser supports a fractional‐frequency stability of at an averaging time of 20 millisecond, at 300 second, an integrated linewidth of 25 Hz that results from thermal noise, frequency noise floor as low as 0.06 Hz2 Hz−1, and a passive vibration immunity as low as 10−10 g−1. The present work explores hybrid laser systems with monolithic photonic and atomic packages based on physical design.
Direct Nanoimprint Lithography of Polyethersulfone Using Cellulose‐Based Mold
Authors: Takei Satoshi 
Published: March 2020

AbstractPolyethersulfone (PES) with a glass transition temperature of 224 °C is a class of high‐performance super engineering plastics with excellent heat resistance, as well as mechanical, electrical, and optical properties. However, the nanopatterning of PES using thermal nanoimprint lithography at a high temperature can induce technical difficulties. High‐accuracy 900‐nm line patterning of PES is fabricated 50 times using both a solvent‐permeable cellulose‐based mold and dimethylformamide as a dilution solvent in direct thermal nanoimprint lithography. The use of dilution solvents in PES has yet been limited in the nanoimprint lithography, and the developed processes expand the surface patterning of super engineering plastic.
Consumer relationship fading
Authors: Evanschitzky Heiner , Ramaseshan B. , Brady Michael K. , Rabbanee Fazlul K. , Brock Christian , Pokorska‐Zare Joanna 
Published: March 2020

AbstractThis paper explores the phenomenon of consumer relationship fading with a series of three adjacent studies. Analyzing two longitudinal behavioral datasets, Study 1 shows that about one‐third of the relationships could be described as fading. Drawing on prior work in the marriage disaffection literature, Study 2 defines relationship fading for the consumer marketing context as a process of gradual decline in consumers' intention to continue their relationship with a brand, generally manifested in negative feelings toward the brand, diminishing frequency and/or volume of transactions with it, and initiation of switching intentions. It further identifies disillusion, disaffection, and crossroads as three distinct fading stages, and outlines boundary conditions. Study 3 observes relationship fading through a diary study approach and finds attitude movement in both positive and negative directions between the stages. Further, while positive attitudes generally decline over the course of the fading trajectory, negative emotions peak at the penultimate fading stage and then level off at the final, crossroads stage. By defining and analyzing consumer relationship fading, we improve understanding of an under‐researched, large segment of consumers.
Saccharide analog, 2‐deoxy‐d‐glucose enhances 4‐1BB‐mediated antitumor immunity via PD‐L1 deglycosylation
Authors: Kim Bareun , Sun Ruoxuan , Oh Wonkyung , Kim Alyssa Min Jung , Schwarz Johann Richard , Lim Seung‐Oe 
Published: March 2020

AbstractTriple‐negative breast cancer (TNBC) lacks a well‐defined molecular target and is associated with poorer outcomes compared to other breast cancer subtypes. Programmed cell death protein 1 (PD‐1)/programmed death‐ligand 1 (PD‐L1) blockade therapy shows a 10% to 20% response rate in TNBC patients. Our previous studies show that PD‐L1 proteins are heavily glycosylated in TNBC, and the glycosylation plays an important role in the PD‐L1 protein's stability and immunosuppressive function. However, a strategy for PD‐L1 deglycosylation in TNBC is poorly defined. Here we found that a saccharide analog, 2‐deoxy‐
d‐glucose (2‐DG), inhibits glycosylation of PD‐L1 and its immunosuppressive function by combining with EGFR inhibitor, gefitinib. Interestingly, 2‐DG/gefitinib‐induced deglycosylation of PD‐L1 decreased the expression level of PD‐L1 protein as well as its binding with PD‐1. However, there was no significant decrease in 4‐1BB expression and its binding with 4‐1BBL by 2‐DG/gefitinib. Furthermore, we demonstrated that the combination treatment of 2‐DG/gefitinib and 4‐1BB antibody enhances antitumor immunity in TNBC syngeneic murine models. Together, our results suggest a new immunotherapeutic strategy to enhance antitumor immunity by PD‐L1 deglycosylation and 4‐1BB stimulation in TNBC.
ASPEN Consensus Recommendations for Refeeding Syndrome
Authors: da Silva Joshua S. V. , Seres David S. , Sabino Kim , Adams Stephen C. , Berdahl Gideon J. , Citty Sandra Wolfe , Cober M. Petrea , Evans David C. , Greaves June R. , Gura Kathleen M. , Michalski Austin , Plogsted Stephen , Sacks Gordon S. , Tucker Anne M. , Worthington Patricia , Walker Renee N. , Ayers Phil ,   Parenteral Nutrition Safety and Clinical Practice Committees, American Society for Parenteral and Enteral Nutrition
Published: March 2020

AbstractIntroductionIn the spring of 2017, the American Society for Parenteral and Enteral Nutrition (ASPEN) Parenteral Nutrition Safety Committee and the Clinical Practice Committee convened an interprofessional task force to develop consensus recommendations for identifying patients with or at risk for refeeding syndrome (RS) and for avoiding and managing the condition. This report provides narrative review and consensus recommendations in hospitalized adult and pediatric populations.MethodsBecause of the variation in definitions and methods reported in the literature, a consensus process was developed. Subgroups of authors investigated specific issues through literature review. Summaries were presented to the entire group for discussion via email and teleconferences. Each section was then compiled into a master document, several revisions of which were reviewed by the committee.Findings/RecommendationsThis group proposes a new clinical definition, and criteria for stratifying risk with treatment and screening strategies. The authors propose that RS diagnostic criteria be stratified as follows: a decrease in any 1, 2, or 3 of serum phosphorus, potassium, and/or magnesium levels by 10%–20% (mild), 20%–30% (moderate), or >30% and/or organ dysfunction resulting from a decrease in any of these and/or due to thiamin deficiency (severe), occurring within 5 days of reintroduction of calories.ConclusionsThese consensus recommendations are intended to provide guidance regarding recognizing risk and identifying, stratifying, avoiding and managing RS. This consensus definition is additionally intended to be used as a basis for further research into the incidence, consequences, pathophysiology, avoidance, and treatment of RS.
Turkish delight a public affairs study on family business: The influence of owners in the entrepreneurship orientation of family‐owned businesses
Authors: Harris Phil , Ozdemir Ozlem 
Published: March 2020

Family‐owned businesses (FOBs) are as unique as the families that own and control them. As reported by Miller, Steier, and Le Breton‐Miller (2003, p.513), the founders of many of these businesses try to continue their legacy and ensure continued family control via intergenerational succession, as when they hand over leadership to their children. The initial statistics suggest only approximately one third of FOBs survive into the second generation, with just 12% remaining “viable” by the third, and only about 3% operating into the fourth generation or beyond. Thus, one of the central problems for FOBs is this inability to ensure competent cross‐generational family leadership through successful transfer of ownership and management to the next family generation. This is a core issue for the modern public affairs practitioner and policy maker, nationally and internationally, and the Turkish case is a good example of the multicomplex issues evident in succession planning and leadership for business founders and leaders in these organisations.A firm's strategic orientation is an indicator of the processes developed to integrate new information, to coordinate decisions, to examine the evolution of environmental factors, and to assess new projects (Escriba‐Esteve, Sanchez‐Peinado & Sanchez‐Peinado, 2009). However, few studies have provided a framework that jointly analyses the FOB owner characteristics, the mediating processes and attitudes by which owners shape the direction of their family firms, and the effect of these postures on firm performance.This paper addresses the influence of family business owner, over the behaviour of FOBs. By treating FOB owners' characteristics as predictors of a firm's strategic orientation, we seek to provide a deeper understanding of how the characteristics of FOB owners shape decision making process and FOBs' behaviours in order to successfully survive in generations. This study introduced the concept of FOB's entrepreneurship orientation (EO) as a variable that mediates between FOB owners' characteristics and business performance. The objective of this paper is twofold: (a) to identify the demographic predictors FOBs' EO and (b) to analyse the role of EO as a mediator of the relationship between FOB owners' characteristics and FOBs' performance.
Die Eismonde von Uranus, Neptun und Pluto
Authors: Wagner Roland 
Published: March 2020

ZusammenfassungDie Eismonde von Uranus, Neptun und Pluto wurden bislang nur von zwei Raumsonden erforscht: Voyager 2 und New Horizons. Ihre Aufnahmen zeigen eine große Vielfalt an Oberflächenformationen. Diese Eismonde weisen Ähnlichkeiten mit denen von Jupiter und Saturn auf. So gibt es offensichtlich auch im äußersten Bereich des Sonnensystems Kryovulkanismus. Auch Dehnungsstrukturen und mögliche Auswirkungen von planetaren Kollisionen sind erkennbar. Mehr als 50 Jahre nach Voyager 2 gibt es Pläne für eine neue Mission ins Uranus‐ und Neptunsystem. Noch weitgehend unerforscht sind die Zwergplaneten und kleineren Körper im Kuiper‐Gürtel. Der Vorbeiflug an Pluto und Charon im Juli 2015 war ein erster Blick in diese noch sehr fremde Welt. Entwürfe für weitere Missionen in den Kuiper‐Gürtel, zumindest seitens der NASA, existieren bereits auf dem Reißbrett für die Zeit nach 2040.
Highly cross‐linked UV‐cured siloxane copolymer networks as icephobic coatings
Authors: Coady Matthew J. , Getangama Nuwansiri N. K. , Khalili Aria , Wood Michael , Nielsen Kent E. , de Bruyn John R. , Hutter Jeffrey L. , Klassen Robert J. , Kietzig Anne‐Marie , Ragogna Paul J. 
Published: March 2020

AbstractPreventing ice growth on infrastructure, vehicles, and appliances remains a significant engineering challenge. Damage caused by ice growth on these installations can be expensive to repair, and their failure can be dangerous. Materials such as cross‐linked polymer networks make effective anti‐ice coatings and can prevent ice growth: reducing the cost of infrastructure repairs and limiting downtime. A link between cross‐link density and ice adhesion has been demonstrated, such that lower cross‐link density materials tend toward lower ice adhesion. Here we describe a method of lowering cross‐link density by incorporating the covalently bound comonomers methyl methacrylate, lauryl methacrylate, and styrene into UV‐cured PDMS‐based polymer networks. Cross‐link density, hardness, surface roughness, and ice adhesion on these materials are tested, showing the influence of comonomer proportions on their properties. Durability is found to increase with the addition of 5, 10, and 25 wt% comonomer, with little to no effect on ice adhesion until 25 wt%, where increases in ice adhesion are observed. Coatings show promisingly low ice adhesion of ~50 kPa, maintaining this low adhesion for up to 50 deicing cycles.
Combination of several matching adjusted indirect comparisons (MAICs) with an application in psoriasis
Authors: Saure Daniel , Schacht Alexander , Kadziola Zbigniew , Brnabic Alan J. M. 
Published: March 2020

SummaryIn health technology assessment (HTA), beside network meta‐analysis (NMA), indirect comparisons (IC) have become an important tool used to provide evidence between two treatments when no head‐to‐head data are available. Researchers may use the adjusted indirect comparison based on the Bucher method (AIC) or the matching‐adjusted indirect comparison (MAIC). While the Bucher method may provide biased results when included trials differ in baseline characteristics that influence the treatment outcome (treatment effect modifier), this issue may be addressed by applying the MAIC method if individual patient data (IPD) for at least one part of the AIC is available. Here, IPD is reweighted to match baseline characteristics and/or treatment effect modifiers of published data. However, the MAIC method does not provide a solution for situations when several common comparators are available. In these situations, assuming that the indirect comparison via the different common comparators is homogeneous, we propose merging these results by using meta‐analysis methodology to provide a single, potentially more precise, treatment effect estimate. This paper introduces the method to combine several MAIC networks using classic meta‐analysis techniques, it discusses the advantages and limitations of this approach, as well as demonstrates a practical application to combine several (M)AIC networks using data from Phase III psoriasis randomized control trials (RCT).
Quantum Monte Carlo study of ground and first excited state of C, N, O, F, and Ne atoms using Slater‐Jastrow‐Backflow wave function
Authors: Nasiri Saeed , Zahedi Mansour 
Published: March 2020

AbstractAll‐electron fixed‐node diffusion quantum Monte Carlo energies of the two lowest‐lying states of C, N, O, F, and Ne atoms are reported. The Slater‐Jastrow form is used as the trial wave function. We will use single‐ and multideterminant wave functions as the Slater part. The single‐determinant wave function has been computed by the Hartree‐Fock method and the multideterminant wave functions have been computed by the complete active space self‐consistent field, configuration interaction with single and double excitation, configuration interaction with single, double, triple, and quadruple excitation and second‐order configuration interaction. For the ground‐ and first excited states, the multideterminant wave functions have computed more than 99% of the correlation energy. Significant improvements have been achieved using the backflow transformations and up to 99.8% of the correlation energy has been recovered. A very good agreement with the experimental data has been obtained for the excitation energies.
On performance recovery of robust dynamic surface control
Authors: Pan Yongping , Joo Young‐Hoon , Yu Haoyong 
Published: March 2020

SummaryRobust dynamic surface control (RDSC) is effective in alleviating the implementation difficulty of backstepping‐based multiple‐surface sliding control (MSSC) for a class of strict‐feedback nonlinear systems with mismatched uncertainties. However, the synthesis and analysis of the classical RDSC are conservative, which not only may lead to an impractical control law but also cannot fully reveal the technical nature of RDSC. This article provides a comprehensive study of a preferred RDSC law with an approximation of the signum function based on the singular perturbation theory. By formulating the control problem into a singular perturbation form, it is proven that the preferred RDSC recovers the performance of MSSC as the decrease of a filter parameter. The attractive features of the preferred RDSC revealed during the proposed synthesis and analysis include: (a) the control gain can be significantly reduced resulting in a sharp decrease of control energy and (b) the closed‐loop stability can be guaranteed by only decreasing the filter parameter. Simulation results have been shown to be consistent with the theoretical findings.
Has a non‐native cichlid of the genus Amatitlania (Actinopterygii, Cichlidae) adapted to the headwaters in Brazilian semi‐arid?
Authors: Gurgel‐Lourenço Ronaldo C. , Pinto Leonardo M. , Bezerra Luis A. V. , Sánchez‐Botero Jorge I. 
Published: March 2020

AbstractSeveral fish species from Central America and other regions have been introduced into Brazil. In this study, we evaluated the bioecological aspects of a non‐native cichlid of the genus Amatitlania (convict cichlid) and its possible establishment in high‐altitude forest enclaves of semi‐arid Northeastern Brazil. Specimens of Amatitlania nigrofasciata (Günther, 1867) were captured in a local stream displaying abiotic conditions like those of its natural range of distribution. The individuals collected were predominantly adult, insectivorous and displayed normal length–weight relationships, although we observed some phenotypical plasticity (variation in body depth, and a morphologically abnormal dorsal fin in three cases). Our results indicate that A. nigrofasciata has successfully colonized an Atlantic forest enclave in the Brazilian semi‐arid region, making it necessary to adopt measures to prevent the species from spreading to other water bodies in the surroundings.