bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integral abutment bridges: Investigation of seismic soil‐structure interaction effects by shaking table testing
Authors: Fiorentino Gabriele , Cengiz Cihan , De Luca Flavia , Mylonakis George , Karamitros Dimitris , Dietz Matt , Dihoru Luiza , Lavorato Davide , Briseghella Bruno , Isakovic Tatjana , Vrettos Christos , Topa Gomes Antonio , Sextos Anastasios , Nuti Camillo 
Published: December 2020

AbstractIn recent years there has been renewed interest on integral abutment bridges (IABs), mainly due to their low construction and maintenance cost. Owing to the monolithic connection between deck and abutments, there is strong soil‐structure interaction between the bridge and the backfill under both thermal action and earthquake shaking. Although some of the regions where IABs are adopted qualify as highly seismic, there is limited knowledge as to their dynamic behaviour and vulnerability under strong ground shaking. To develop a better understanding on the seismic behaviour of IABs, an extensive experimental campaign involving over 75 shaking table tests and 4800 time histories of recorded data, was carried out at EQUALS Laboratory, University of Bristol, under the auspices of EU‐sponsored SERA project (Seismology and Earthquake Engineering Research Infrastructure Alliance for Europe). The tests were conducted on a 5 m long shear stack mounted on a 3 m × 3 m 6‐DOF earthquake simulator, focusing on interaction effects between a scaled bridge model, abutments, foundation piles and backfill soil. The study aims at (a) developing new scaling procedures for physical modelling of IABs, (b) investigating experimentally the potential benefits of adding compressible inclusions (CIs) between the abutment and the backfill and (c) exploring the influence of different types of connection between the abutment and the pile foundation. Results indicate that the CI reduces the accelerations on the bridge deck and the settlements in the backfill, while disconnecting piles from the cap decreases bending near the pile head.
A German version of the Caregiver Skills scale for caregivers of patients with anorexia nervosa
Authors: Zeiler Michael , Philipp Julia , Truttmann Stefanie , Wittek Tanja , Franta Claudia , Imgart Hartmut , Zanko Annika , Auer‐Welsbach Ellen , Kahlenberg Leonie , Wagner Gudrun , Karwautz Andreas 
Published: December 2020

AbstractObjectiveTo investigate acceptance, reliability, convergent validity, factor structure and sensitivity to change of a German translation of the Caregiver Skills (CASK) scale measuring skills related to caring for patients with eating disorders.MethodsTwo hundred and thirty‐three parents (76% female) of adolescent patients (mean age 15.1) with anorexia nervosa (AN) completed the 27 items of the CASK. We calculated item/scale characteristics, internal consistencies and bivariate correlations with other measures of caregiving burden. We evaluated goodness‐of‐fit of the 6‐factor model using confirmatory factors analysis and explored the sensitivity to change following two skills‐based trainings.ResultsThe fit of the 6‐factor model was acceptable (Root Mean Square Error of Approximation: 0.077, Standard Root Mean Square Residual: 0.080). Cronbach's alpha was excellent for the total (.94) and acceptable for all subscales (0.73–0.85). The total CASK score was 68.04 (max. 100) showing relatively high self‐rated caregiver skills. Non‐completion rates of most items were low (<3%) indicating high acceptance. Convergent validity was found with measures of psychological distress, depression, anxiety and expressed emotion. The total score significantly increased following an 8‐week workshop/online skills training (d = 0.70) and a 2‐day multi‐family intervention (d = 0.47).DiscussionThe German CASK version is a useful instrument to assess caregiver skills in parents of patients with AN and to evaluate outcomes of skills‐based trainings.
Accumulation of Contaminants by Wild Turkeys and Potential for Consumer Exposure
Authors: Tisdale Cody A. , Leaphart James C. , Beasley James C. , Martin James A. 
Published: December 2020

Abstract
Despite their popularity as a game species across North America, little is known about contaminant burdens in wild turkeys (Meleagris gallopavo) inhabiting areas of environmental contamination, and their potential to expose human and wildlife consumers. We compared trace element concentrations and radionuclide activity in muscle and liver tissues of turkeys inhabiting the Savannah River Site (USA), an area with known anthropogenic contaminant inputs, with turkeys from uncontaminated areas offsite. In addition, we tested breast feathers from a subset of individuals for mercury (Hg) to assess the viability of nonlethal sampling for quantifying Hg concentrations. Finally, we quantified arsenic, Hg, and selenium (Se) in blood of live-captured turkeys inhabiting a coal ash basin on the Savannah River Site. Compared with reference samples, we found that turkeys inhabiting the Savannah River Site contained elevated Hg levels in both muscle and liver tissues, and lower concentrations of chromium. Turkeys from the ash basin also had elevated levels of Se. We found a positive correlation between breast muscle and feather Hg concentrations (F1,59 = 267.5, R2 = 0.82, p &lt; 0.001), suggesting that feathers can potentially be used as a nonlethal sampling technique. All elements analyzed were below reference limits set by the Centers for Disease Control and Prevention for safe consumption. Thus, our data suggest that turkeys likely are not an important pathway of contaminant exposure on the Savannah River Site or other areas with similar contaminant distributions. Environ Toxicol Chem 2021;40:1222–1231. © 2020 SETAC
Low‐complexity subspace method for I/Q imbalance estimation in low‐IF receivers with unknown fading
Authors: Gomaa Ahmad , Elezabi Ayman , Eissa Mohamed H. 
Published: December 2020

AbstractIn low‐intermediate‐frequency (low‐IF) receivers, I/Q imbalance (IQI) causes interference on the desired signal from the blocker signal transmitted over the image frequencies. Conventional approaches for pilot‐aided IQI estimation in zero‐IF receivers are not applicable to low‐IF receivers, where the image interference is unknown at the receiver. We propose a low‐complexity subspace method for the estimation of IQI parameters in low‐IF receivers in the presence of unknown fading, where we utilize knowledge of the pilots to null out the signal part. This reduces the variance of the sample mean estimate and leads to faster convergence. The proposed nulling method offers significantly better image rejection at low input signal‐to‐interference power ratio (SIR) than existing methods. Performance analysis of the output SIR as well as computer simulations are also provided.
Assessing the state of knowledge of contemporary climate change and primates
Authors: Bernard Andrew B. , Marshall Andrew J. 
Published: December 2020

AbstractIn recent years, interest in understanding the effects of climate change on species and ecological systems has sharply increased. We quantify and contextualize the current state of knowledge about the effects of contemporary climate change on non‐human primates, a taxon of great ecological and anthropological significance. Specifically, we report findings from a systematic literature search designed to assess the allocation of research effort on primates and climate change and consider how the current distribution of knowledge may be influencing our understanding of the topic. We reveal significant phylogenetic and geographic gaps in our knowledge, which is strongly biased towards lemurs, apes, and a relatively small subset of primate range countries. We show that few analyses investigate changes in primate foods relative to changes in primates themselves or their habitats, and observe that few longitudinal datasets are of sufficient duration to detect effects on the generational scale. We end by identifying areas of research inquiry that would advance our theoretical understanding of primate ecology, evolution, and adaptability, and meaningfully contribute to primate conservation.
Price discovery in chinese agricultural futures markets: A comprehensive look
Authors: Yang Jian , Li Zheng , Wang Tao 
Published: December 2020

AbstractThis study investigates price discovery performance for the 11 most traded agricultural commodity futures in China, proposing an improved recursive cointegration analysis. Despite a relatively short trading history and being subject to various policy interventions, China's agricultural futures markets generally play a more dominant role in the price discovery process as the markets become mature, even with further allowance for time variations and regional variations in the price discovery process. Additional analysis reveals various determinants of the contribution of futures versus local cash market prices in the price discovery process. There may also be seriously misleading inferences drawn from using nearby futures data in China.
Quantile information share under Markov regime‐switching
Authors: Lien Donald , Wang Ziling , Yu Xiaojian 
Published: December 2020

AbstractThis paper introduces a new quantile information share (QIS) method by extending the conventional QIS to Markov regime‐switching models. For most commodities in the full sample, our results show that the relationship among the spot QIS, the spot return quantile, and the futures return quantile is displayed by a saddle surface or a half saddle surface. The information share (IS) of the futures markets is saddle shaped in the low‐ and high‐volatility states. Moreover, the spot market has a larger IS in the low‐volatility state than that in the high‐volatility state for most commodities.
YAP and TAZ regulate Schwann cell proliferation and differentiation during peripheral nerve regeneration
Authors: Jeanette Haley , Marziali Leandro N. , Bhatia Urja , Hellman Abigail , Herron Jacob , Kopec Ashley M. , Feltri Maria Laura , Poitelon Yannick , Belin Sophie 
Published: December 2020

AbstractYAP and TAZ are effectors of the Hippo pathway that controls multicellular development by integrating chemical and mechanical signals. Peripheral nervous system development depends on the Hippo pathway. We previously showed that loss of YAP and TAZ impairs the development of peripheral nerve as well as Schwann cell myelination. The role of the Hippo pathway in peripheral nerve regeneration has just started to be explored. After injury, Schwann cells adopt new identities to promote regeneration by converting to a repair‐promoting phenotype. While the reprogramming of Schwann cells to repair cells has been well characterized, the maintenance of such repair phenotype cannot be sustained for a very long period, which limits nerve repair in human. First, we show that short or long‐term myelin maintenance is not affected by defect in YAP and TAZ expression. Using crush nerve injury and conditional mutagenesis in mice, we also show that YAP and TAZ are regulators of repair Schwann cell proliferation and differentiation. We found that YAP and TAZ are required in repair Schwann cells for their redifferentiation into myelinating Schwann cell following crush injury. In this present study, we describe how the Hippo pathway and YAP and TAZ regulate remyelination over time during peripheral nerve regeneration.
Sequential Two‐Fold Claisen Rearrangement, One‐Pot Ring‐Closing Metathesis and Cross‐Metathesis as a Route to Substituted Benzo[b]azepine‐2‐one, Benzo[b]azepine and Benzo[b]oxepine Derivatives
Authors: Mandal Shyamasankar , Banerjee Jeet , Maity Sougata , Chattopadhyay Shital K. 
Published: December 2020

AbstractA synthetic protocol involving sequential use of three atom‐economic processes viz. Claisen rearrangement, ring‐closing metathesis and cross metathesis has been developed to access 7‐substituted benzo[b]azepine and benzo[b]oxepine derivatives starting from appropriate aniline or phenol in good overall yield. A one‐pot RCM‐CM protocol has also been developed for the synthesis of benzazepine and benzoxepine derivatives.
Measures of curiosity: A literature review
Authors: Wagstaff M. Fernanda , Flores Gabriela L. , Ahmed Rawia , Villanueva Sarah 
Published: December 2020

AbstractWe present an assessment of curiosity measures used in organizational and social psychology literature published since the start of this century. We focus on: (a) the validity and reliability of existing measures; (b) the main dimensions tapping the operationalization of the constructs; and (c) the use of each measure in organizational settings. We identify implications of the use of each of these measures for theory and practice in the field of human resource development. Our study concludes with an assessment of the contexts in which the available measures of curiosity may be used and potential challenges in the application of these measures to further the field of human resource development. We find that curiosity measures may be most useful in organizational contexts where learning occurs, including training, socialization, collaboration, research and development, selection, global management, innovation, creativity, and career change.
Clinicopathologic, genomic and protein expression characterization of 356ROS1fusion driven solid tumors cases
Authors: Huang Richard S. P. , Haberberger James , Sokol Ethan , Schrock Alexa B. , Danziger Natalie , Madison Russell , Trabucco Sally , Jin Dexter , Pavlick Dean , Ramanan Vivek , Hole Kanchan , McGregor Kimberly , Venstrom Jeffrey , Ross Jeffrey S. 
Published: December 2020

AbstractBased on the approvals of crizotinib and entrectinib by the Food and Drug Administration for the treatment of ROS1 positive nonsmall cell lung cancer (NSCLC), we sought to examine the mutational profile of a variety of solid tumors (excluding sarcomas) withROS1fusions that underwent comprehensive genomic profiling. A review of our database was performed to extract all nonsarcoma patients withROS1fusions that were discovered by the hybrid capture‐based DNA only sequencing assays. We examined the coalterations representing potentially targetable biomarkers, resistance alterations and other alterations in these cases. In addition, we examined the histologic characteristics and protein expression with immunohistochemistry (IHC). From a series of clinically advanced nonsarcoma solid tumors, 356 unique cases withROS1fusions included 275 (77.2%) NSCLC and 81 (22.8%) non‐NSCLC. Ten novelROS1fusions were discovered. Importantly, the NSCLCROS1fusionpostumors had a higher PD‐L1 IHC expression positivity when compared to the NSCLCROS1fusionnegpopulation (P= .012, Chi‐squared). The frequency of known and likely anti‐ROS1targeted therapy resistance genomic alterations in NSCLC was 7.3% (20/275) and in non‐NSCLC was 4.9% (4/81). Overall, the coalteration profile ofROS1fusionposNSCLC and non‐NSCLC was similar with only three genes altered significantly more frequently in non‐NSCLC vs NSCLC:TERT,PTEN,APC. In our study, we characterized a large cohort ofROS1fusionposNSCLC and non‐NSCLC solid tumors and discovered 10 novelROS1fusions.
RETRACTED: Safety and efficacy of titrated oral misoprostol solution versus vaginal dinoprostone for induction of labor: A single‐center randomized control trial
Authors: Wang Xiu , Zhang Chao , Li Xia , Qi Hongyan , Liu Qing , Lei Jing 
Published: December 2020

AbstractObjectiveTo compare the efficacy and safety of the hourly administration of titrated oral misoprostol solution (OMS) and vaginal dinoprostone for induction of labor.MethodsTitrated OMS was administrated hourly for induction of labor, starting with a dose of 20 µg and terminating at a dose of 50 µg. The safety and efficacy of OMS were compared with that of vaginal dinoprostone for induction of labor.ResultsFrom June 2016 to October 2019, 2280 (78.3%) and 2115 (72.9%) women who received titrated OMS and vaginal dinoprostone, respectively, had a vaginal delivery (P = 0.005). Cesarean delivery was performed in 632 (21.7%) and 783 (27.0%) women who received titrated OMS and vaginal dinoprostone, respectively (P = 0.008). Tachysystole with changes in fetal heart rate (FHR) was seen in 104 (3.6%) and 249 (8.6%) women in the OMS and dinoprostone groups, respectively (P = 0.007). The frequency of non‐reassuring FHR was lower in the OMS group compared to the dinoprostone group (P = 0.006).ConclusionThe titrated OMS has an efficacy comparable to vaginal dinoprostone. Moreover, it causes a lower incidence of cesarean delivery, lower frequency of tachysystole with changes in FHR, and non‐reassuring FHR.
Are effect sizes in self‐efficacy field changing over time? A meta–meta analysis
Authors: Jiao Xinian , Yu Xiyan , Wang Shuyuan , Wang Zishan , Gong Zhun 
Published: December 2020

Theories relating to self‐efficacy have developed rapidly since Bandura first proposed the concept in 1977. In the past two decades, psychologists have carried out numerous studies to research the cultural and psychological changes in social development. The research topic of this study is whether self‐efficacy changes over time. This study uses a meta–meta analysis and includes 13 meta‐analyses, including 536 effect sizes, with a total sample size of 421,880. We find that individual self‐efficacy increases over time, which may be related to social development trends. However, the effects of interventions on self‐efficacy remain similar (Qmodel = 1.807, df = 1, p > .05), and a possible explanation is that time effects of self‐efficacy confuse the effects of intervention, because both in the intervention group and control group, the average of self‐efficacy increases over time. And we find that a general decline in the predictive effects of self‐efficacy (Qmodel = 5.117, df = 1, p = .024), especially the ability to predict relatively objective variables (e.g. job performance, teaching effectiveness, and transfer of training). A possible explanation is that as social development people tend to overestimate their self‐efficacy. Another possible explanation is that the effect sizes in the original studies being overrated, may due to intentional selective reporting or unintentional statistical errors.
Enhancer of zeste homolog 2 participates in the process of atherosclerosis by modulating microRNA‐139‐5p methylation and signal transducer and activator of transcription 1 expression
Authors: Zheng Xuwei , Zhao Xiaoyan , Han Zhanying , Chen Kui 
Published: December 2020

AbstractAtherosclerosis (AS) is the main cause of coronary heart disease, in which enhancer of zeste homolog 2 (EZH2) has been implied to participate in this process. Thus, this work proposed to explore the effect of EZH2 on AS from microRNA‐139‐5p (miR‐139‐5p)/signal transducer and activator of transcription 1 (STAT1) axis. EZH2, miR‐139‐5p, and STAT1 expression in arterial tissues of AS patients were detected. Human arterial smooth muscle cells (HASMCs) induced with oxidized low‐density lipoprotein (ox‐LDL) and the mice fed with high fat diet were treated with silenced EZH2 or upregulated miR‐139‐5p to explore their roles in proliferation and apoptosis of HASMCs, together with inflammation response and oxidative stress of mice. Chromatin immunoprecipitation experiment was applied to verify the regulatory effect of EZH2 on miR‐139‐5p through methylation of H3K27me3. The targeting relationship between miR‐139‐5p and STAT1 was verified by online website and luciferase activity assay. Reduced miR‐139‐5p and overexpressed EHZ2 and STAT1 were found in AS. Silenced EZH2 or elevated miR‐139‐5p decreased the production of cholesterol and inhibited inflammation reaction in serum of mice with AS. Silenced EZH2 or elevated miR‐139‐5p facilitated proliferation and restrained apoptosis of ox‐LDL‐treated HASMCs, and restrained oxidative stress and cell apoptosis in arterial tissues of AS mice. EZH2 regulated miR‐139‐5p through H3K27me3, and miR‐139‐5p targeted STAT1. miR‐139‐5p silencing antagonized the effects of EZH2 down‐regulation on AS. This study manifests that down‐regulated EZH2 or elevated miR‐139‐5p inhibits ox‐LDL‐induced HASMCs apoptosis, plaque formation, and inflammatory response in AS mice, which may be related to down‐regulated STAT1.
A comparative study on the effects of three different metals (Cu, Zn and Cd) at similar toxicity levels in common carp, Cyprinus carpio
Authors: Castaldo Giovanni , Delahaut Vyshal , Slootmaekers Bart , Bervoets Lieven , Town Raewyn M. , Blust Ronny , De Boeck Gudrun 
Published: December 2020

AbstractTo improve our understanding of underlying toxic mechanisms, it is important to evaluate differences in effects that a variety of metals exert at concentrations representing the same toxic level to the organism. Therefore, the main goal of the present study was to compare the effects of waterborne copper (Cu(II)), zinc (Zn(II)) and cadmium (Cd (II)) on a freshwater fish, the common carp (Cyprinus carpio), at concentrations being 0%, 25%, 50% and 100% of the 96 h LC50 (the concentration which is lethal to 50% of the population in 96 h). All the exposures were performed for a period of 1 week at 20°C. Our results show a rapid increase in the amount of copper and cadmium accumulated in the gills, while zinc only started to increase by the end of the experiment. All three metal ions increased metallothionein gene expression in both gills and liver. However, clear adverse effects were mainly observed for the Cu exposed group. Cu caused a decrease in Na level in gill tissue; it altered the expression of genes involved in ionoregulation such as Na+/K+‐ATPase and H+‐ATPase as well as the expression of oxidative stress‐related genes, such as catalase, glutathione reductase and glutathione S‐transferase. Zinc and cadmium exposure did not alter the ion levels in the gills. In addition, no obvious effect of oxidative stress was observed, except for a transient increase in glutathione reductase at the highest cadmium concentration.
Attenuation corrected‐optical coherence tomography for quantitative assessment of skin wound healing and scar morphology
Authors: Ghosh Biswajoy , Mandal Mousumi , Mitra Pabitra , Chatterjee Jyotirmoy 
Published: December 2020

AbstractImaging the structural modifications of underlying tissues is vital to monitor wound healing. Optical coherence tomography (OCT) images high‐resolution sub‐surface information, but suffers a loss of intensity with depth, limiting quantification. Hence correcting the attenuation loss is important. We performed swept source‐OCT of full‐thickness excision wounds for 300 days in mice skin. We used single‐scatter attenuation models to determine and correct the attenuation loss in the images. The phantom studies established the correspondence of corrected‐OCT intensity (reflectivity) with matrix density and hydration. We histologically validated the corrected‐OCT and measured the wound healing rate. We noted two distinct phases of healing—rapid and steady‐state. We also detected two compartments in normal scars using corrected OCT that otherwise were not visible in the OCT scans. The OCT reflectivity in the scar compartments corresponded to distinct cell populations, mechanical properties and composition. OCT reflectivity has potential applications in evaluating the therapeutic efficacy of healing and characterizing scars.