bluuebunny/crossref_metadata_2025_split huggingface dataset:
A network meta-analysis on comparative efficacy of statins focusing for prevention of contrast-induced acute kidney injury in chronic kidney disease patients undergoing percutaneus coronary intervention
Authors: Rahman Ilham Akbar , Purnamasari Yeni , Rewa Vicky Nanu , Kasyim Hasyim , Umar Abd Rahman , Kasim Firdaus 
Published: April 2020

Background: The use of interventional diagnostic and therapeutic procedures required intravascular iodinated contrast are performed in millions of patients worldwide and are steadily increasing the risks of contrast-induced acute kidney injury (CI-AKI). Statins are primarily used in cardiovascular medicine for their lipid-lowering effects but they possess remarkable pleiotropic effects such as improving endothelial function as well as decreasing oxidative stress and inflammation. A network meta-analysis was carried out to evaluate the effect of different statins in prevention of CI-AKI and also to investigate which type and dose of statins maybe the best choice specifically in CKD patients who have higher risk.Â Methods: We performed a pairwise and network meta analysis of 14 randomized studies (9847 patients) comparing a total of 6 different statins: rosuvastatin high dose, atorvastatin high dose, simvastatin high dose, rosuvastatin regular dose, atorvastatin regular dose, pravastatin regular dose versus each other and versus placebo in CKD patients undergoing PCI with iodinated contrast for prevention of CIAKI. Google Scholar, Pubmed, Science Direct databases were searched up to May 2019. The data were pooled using STATA, and R version statistics calculating odds ratios (ORs) with 95% confidence intervals. Results: Statin loading before contrast administration was associated with a significantly reduced risk of CI-AKI in patients with CKD undergoing cardiac catheterization (pooled OR= 0.51; P=0.0001). Regular dose pravastatin comprised the best effect size for a reduction in CIAKI risk (OR = 0.32, 95% CI 0.14-0.72, p=0.006). Regular dose pravastatin and high dose atorvastatin were ranked as the highest probability to be the best treatment (Pbest) with 44% and 31% respectively for effect on CIAKI prevention.Conclusion: Preloading with statins is associated with significantly reduced risk of CI-AKI in patients with CKD undergoing cardiac catheterization. Regular dose pravastatin and high dose atorvastatin have the highest probability to be the most effective prevention strategy.
Cerebrospinal fluid contents and risk of shunt exposure in hydrocephalus
Authors: Arifin Muhamad Thohar , Purnomo Febriyanto , Muttaqin Zainal , Bakhtiar Yuriz , Andar Erie , Priambada Dody , Kurnia Happy , Risdianto Ajid , Tsaniadi Krisna , Kusnarto Gunadi , Bunyamin Jacob 
Published: April 2020

Background: Exposure of the shunt is a rare but severe complication after ventriculoperitoneal (VP) shunt placement. It is unclear whether particular levels of cerebrospinal fluids (CSF) protein, glucose, or polymorphonuclears (PMNs) may influence theÂ shuntÂ exposure in high-risk individuals.This study aims to find the relation between CSF parameters and shunt exposure.Methods: Examined preoperative CSF characteristics included CSF colour, protein, glucose, and PMNs content in 513 patients with hydrocephalus. Mann-Whitney test was used to determine the correlation between CSF parameters and shunt exposure.Results: Shunt exposure was detected in 25 cases (4.87%). There was a significant relationship betweenÂ distal tip exposure with preoperative glucose (p=0.000), protein level (p=0.007), or PMNs count (p=0.043).Conclusion: Preoperative CSF contents had a significant correlation with shunt exposure in hydrocephalus patients.
The 3rd Aceh Surgery Update 2019 in Conjugation with The 1st Indonesian General Surgeon Society (PABI) Aceh Chapter Meeting and The 1st Ikatan Alumni Bedah Unsyiah (IABU) Meeting
Authors: Habibie Yopie Afriandi 
Published: April 2020

Assalamuâ€™alaikum Wr. WbÂ Â Praise and gratitude we pray the presence of Allah SWT for all His mercy and guidance we can still work and work to help in the field of education and humanity. With our greetings and prayers, we are praised to the Holy Prophet Rahmatan lil alamin Rasulullah Muhammad SAW who has brought us from the realm of darkness to a world full of knowledge.Â In itâ€™s third year, the 2019 Aceh Surgery Update will be held in conjunction with The 1st Indonesian General Surgeon Society (PABI), Aceh Chapter Meeting and The 1st Unsyiah Surgical Alumni Association (IABU) Annual Meeting, on December 06th â€“ 08th December 2019 at Dr. Zainoel Abidin Hospital and Building D Multipurpose Auditorium F-MIPA Universitas Syiah Kuala Banda Aceh, with the theme of Tips and Traps in Emergency Surgical Daily Practice. The scientific program this time was very special with the presence of the Bali Medical Journal indexed by Web of Science in scientific publications for all topics presented, both in symposium sessions and free papers.Â I would like to welcome all the experts who have been willing to attend to be the resource persons at this scientific event. A big thank you to all the committees and sponsors who helped to make this big activity a great success. Finally, I also welcome to all delegates, I hope you all get a high valuable scientific experience in the Banda Aceh, the City of Gemilang.Â Wassalam,Sincerely yours,Â Â Yopie Afriandi Habibie, MD, SpBTKV-E, FIHA, FICS, FACSChairmanÂ Â
The out of pocket payments in low and middle-income countries and the affecting factors: a systematic review and meta-analysis
Authors: Nemati Esmat , Nosratnejad Shirin , Doshmangir Leila , Zarea Gavgani Vahideh 
Published: April 2020

Introduction:Â The out of pocket (OOP) payment is the most important source of health system financial support in low and middle-income countriesÂ (LMICs); therefore, considering and controlling health expenses are pivotal issues. The present study aimed to determine the households OOP payments inÂ LMICs.Method:Â Electronic databases, including Web of Science, Scopus, and PubMed were searched systematically in September 2015. Relevant papers on OOP payment inÂ LMICsÂ were included in the study. OOP payment was estimated as a percentage of Gross Domestic Product (GDP) per capita and household final consumption expenditureÂ per capita in every country.Results:Â Seventeen papers out of 3714 were included in the study. Eight studies were conducted in low-income countries, eight in middle-income countries, and one in both low and middle-income countries. The mean OOP payment as a percentage of households final consumption expenditureÂ inÂ LMICsÂ was 0.67(Î±= 0.000, CI: 0.35-1.003) and the mean of OOP payment as a percentage of GDP in these countries was 1.65(Î±=0.000, CI: 1.57-1.72).Conclusion:Â The households inÂ LMICsÂ face high levels of OOP payment. Therefore, many challenges must be overcome in financial support of health sectors. Health system policies and strategies are necessary to reform interventions in financing resources and purchasing health care services.
Ulama Network of North Sumatera in Developing Islam in North Sumatera
Authors: Tarigan Azhari Akmal , Nurhayati N. , Nasution M. Syukri Albani 
Published: April 2020

North Sumatera Islam is often left out of Nusantara Islāmic studies. North Sumatera has not become a serious concern of the reviewers of the Islāmic history of the archipelago due to several things. First, North Sumatera Islam is understood as a continuation of Aceh Islam. Secondly, it could be that there is a suspicion that North Sumatera has been identified as a Christian territory from the beginning, although this argument is not strong. This study aims to find out about the communication between fellow scholars in developing science in North Sumatera. Then researchers will look at the role of educational institutions in the development of Islam in North Sumatera. The method used in this research is descriptive qualitative research, which aims to understand social problems, events, the role of interaction, and community groups. The qualitative approach is used by focusing on the social conditions surrounding the existence of the Ulama, who lived in his day, which became the basis in compiling the historical events of the ulama network in the development of Islam in North Sumatera in the XX century. The results of this study are; first, the scientific network among fellow North Sumatera scholars is very good; it shows from the shape of the education system. This can be seen in connection with his teachers in the Middle East. Secondly, the role of Islāmic boarding schools Musthafawiyah and Maktab Islamiyah is very important, including as a producer of scholars in North Sumatera and a center for the study and development of Islamic Law studies in the midst of society.
PEMBELAJARAN MATEMATIKA BERBASIS ALAM DI TK SEKOLAH ALAM BANDUNG (Studi Kasus di TK Sekolah Alam Bandung Tahun Ajaran 2018-2019)
Authors: Agustiani Rini 
Published: April 2020

Penelitian ini dilatarbelakangi oleh situasi dilapangan, dimana pembelajaran matematika yang dilaksanakan di lembaga pendidikan anak usia dini belum sesuai dengan tingkat perkembangan anak, dimana pembelajaran matematika yang diberikan cenderung bersifat akademik seperti mengajarkan konsep matematika dengan metode driil dan paper pencil. Tujuan penelitian ini untuk mengetahui pembelajaran matematika berbasis alam di TK Sekolah Alam Bandung. Penelitian ini menggunakan pendekatan kualitatif dengan desain penelitian studi kasus. Teknik pengumpulan data menggunakan observasi, wawancara, dan studi dokumentasi. Analisis data menggunakan analisis data tematik. Hasil penelitian menunjukan: pertama, Perencanaan pembelajaran matematika berbasis alam di TK Sekolah Alam Bandung dimulai dengan membuat lesson plan, weekly plan, dan action/dynamic plan. Pembelajaran matematika dirancang secara terintegrasi dengan bidang pengembangan sains dan daya pikir. Kedua, pelaksanaan pembelajaran matematika berbasis alam di TK Sekolah Alam Bandung dilaksanakan dilingkungan alam sekitar melalui kegiatan-kegiatan konkrit yang melibatkan anak secara langsung. Kegiatan tersebut meliputi kegiatan pembelajaran matematika dalam kegiatan jelajah alam, pembelajaran matematika dalam kegiatan detektif alam, pembelajaran matematika dalam kegiatan outbond, kegiatan mengumpulkan rumput, menghitung dan menebak bentuk batu, menyusun dan menulis lambang bilangan di atas tanah, mengukur banyak-sedikit air. Melalui kegiatan-kegiatan tersebut anak dapat dengan mudah menguasai konsep matematika sehingga indikator pencapaian kemampuan matematika anak dapat tercapai. Ketiga, penilaian pembelajaran matematika di TK Sekolah Alam Bandung berdasarkan observasi dan tes yang berpedoman pada indikator pembelajaran matematika.
PENERAPAN PENDIDIKAN KARAKTER BERBASIS MANAJEMEN QOLBU DI TK DAARUT TAUHID KOTA BANDUNG
Authors: Khairunnisa Fathul , Zaman Badru , Mariyana Rita 
Published: April 2020

Penelitian ini bertujuan untuk mengetahui penerapan pendidikan karakter berbasis manajemen Qolbu pada anak usia dini di PG TK Daarut Tauhid. Metode yang digunakan dalam penelitian ini adalah Studi Kasus dengan pendekatan kualitatif. Subjek dalam penelitian ini adalah 1 kepala sekolah, 1 wakil kepala sekolah sekaligus wali kelas Play group dan 1 guru TK A sekaligus penyusun kurikulum sekolah. Data penelitian diperoleh melalui wawancara, observasi dan studi dokumentasi. Hasil penelitian menunjukan bahwa penerapan pendidikan karakter yang di terapkan di PG TK Daarut Tauhid berbasis manajemen Qolbu, dimana manajemen Qolbu sendiri merupakan salah satu Misi dari Daarut Tauhid. Kurikulum karakter yang digunakan yaitu Kurikulum Karakter BAKU khas sekolah. Karakter BAKU merupakan panjangan dari Baik dan Kuat, yang meliputi karakter Baik yaitu Ikhlas, Jujur dan Tawadhu, sedangkan karakter Kuat disini meliputi, Disiplin, Berani, dan Tangguh. Penerapan pendidikan karakter diterapkan melalui melalui aktitas rutin atau kegiatan pembiasaan sehari-hari namun lebih di kuatkan setiap hari Jum’at. Sarana dan prasarana, media atau sumber belajar yang ada sudah dapat menunjang terlaksananya penerapan pendidikan karakter berbasis manajemen Qolbu pada anak usia dini di PG TK Daarut Tauhid Kota Bandung.
MENINGKATKAN KECERDASAN KINESTETIK ANAK USIA DINI MELALUI PEMBELAJARAN TARI KIJANG
Authors: Nur'afifah Dina , Kurniawati Leli , Gustiana Asep Deni 
Published: April 2020

Penelitian dilatar belakangi belum berkembangnya kecerdasan kinetetik yang dimiliki anak di kelompok B TK Kemala Bhayangkari 18. Adapun solusi dalam mengatasi permasalahan tersebut yaitu menggunakan pembelajaran Tari Kijang sebagai stimulus gerak anak. Penelitian ini bertujuan untuk mengetahui peningkatan kecerdasan kinestetik anak setelah diterapkan pembelajaran Tari Kijang. Subjek pada penelitian ini berjumlah 15 anak yang terdiri dari 10 orang anak perempuan dan 5 orang anak laki-laki. Metode penelitian yang digunakan penelti yaitu penelitian tindakan kelas (PTK) dengan menggunakan model desain Kemmis dan Mc Taggart yang memiliki empat tahapan penelitian yang terdiri dari perencanaan, pelaksanaan, pengamatan dan refleksi. Instrumen penelitian yang digunakan berupa lembar observasi kecerdasan kinestetik anak (Checklist) dan catatan lapangan. Hasil penelitian terkait kecerdasan kinestetik anak pada siklus I menunjukan persentase sebesar 38% dalam kategori berkembang sangat baik, sedangkan kecerdasan kinestetik anak pada siklus II menunjukan persentase sebesar 80% dalam kategori berkembang sesuai harapan. Hasil penelitian meunjukan bahwa pembelajaran Tari Kijang mampu meningkatkan kecerdasan kinestetik anak usia dini. Maka dari itu, dapat dijadikan sebuah rekomendasi bagi pendidik anak usia dini untuk menerapkan pembelajaran Tari Kijang sebagai salah satu alternatif kegiatan dalam meningkatkan kecerdasan kinestetik anak.
UPAYA ORANG TUA UNTUK MENCEGAH KETERGANTUNGAN ANAK TERHADAP PENGGUNAAN GADGET
Authors: Nurfadilah Fathia , Zaman Badru , Romadona Nur Faizah 
Published: April 2020

Abstrak : Penelitian ini berdasarkan temuan, bahwa saat ini mulai marak penggunaan gadget oleh anak usia dini yang tidak banyak dibatasi waktunya oleh orang tua sehingga menimbulkan ketergantungan. Adapun tujuan penelitian ini untuk mengetahui pandangan dan upaya orang tua dalam mencegah ketergantungan anak terhadap penggunaan gadget. Metode yang digunakan dalam penelitian ini adalah studi kasus. Teknik pengumpulan data menggunakan wawancara. Partisipan dalam penelitian ini sebanyak 2 orang ibu dari anak usia dini yang sering menggunakan gadget. Hasil penelitian menunjukan bahwa pandangan orang tua terhadap penggunaan gadget untuk anak terdapat pendapat positif dan pendapat negatif. Adapun upaya orang tua untuk mencegah ketergantungan anak terhadap penggunaan gadget meliputi: 1) Bersikap tegas dengan melarang anak apabila sudah bermain terlalu lama; 2) tidak mencontohkan menggunakan gadget di depan anak sehingga harus bersembunyi saat menggunakan gadget; 3) mengajak anak untuk bermain diluar dan berinteraksi dengan tetangga dan mengalihkan perhatiannya dengan kegiatan lain; 4) memasukan anak kesekolah agar mengurangi frekuensi anak menggunakan gadget; 5) memberhentikan akses wifi dirumah. Adapun pihak yang membantu dalam pencegahan yaitu dari pihak keluarga yang membantu mengingatkan. Direkomendasikan bagi peneliti selanjutnya agar dapat mengembangkan penelitian lanjutan dengan memperdalam ketergantungan gadget pada anak usia dini ini, dengan desain penelitian lain atau menggunakan sampel yang lebih banyak.
The Addition of Hyaluronic Acid into Platelet-Rich Fibrin Lysate in Restoration of Senescent Human Dermal Fibroblasts Activities
Authors: Azyenela Rika , Julianto Indah , Wirohadidjojo Yohanes Widodo 
Published: April 2020

Senescent human dermal fibroblasts had reduced capacity in proliferation and collagen synthesis. It is due to unresponsiveness against transforming growth factor-β1 (TGF-β1) stimulation. Either platelet-rich fibrin (PRF)-lysate or hyaluronic acid (HA) can restore TGF-β1 signaling pathway.
To determine whether HA addition to PRF lysate has a better activity than PRF-lysate alone in restoring senescent human dermal fibroblasts (HDFs) activities.
HDF isolated from six different human skins was divided into normal HDFs and senescent HDFs which are induced by serum starvation. The senescent groups were then given 50% PRF-lysate and various levels of HA. Amelioration of TGF-β1 signaling was measured by cellular proliferation index and collagen deposition.
Addition of HA into PRF-lysate resulted in a significant increase in proliferation index and collagen deposition index than PRF-lysate alone. The best level of HA for this mixture ranged from 20.83 mM to 41.67 mM. HA in PRF lysate is an excellent candidate material for treating clinical signs related to senescent human dermal fibroblasts.

Ethical permission: This experiment had gain approval from the local ethical committee, Ref: KE/FK/471/EC/2016 dated 17-05-2016.
Morphological Identification, Species Composition and Distribution of Mosquitoes in Kosti region, White Nile State, Central Sudan
Authors: Nour Mai M. , Aboud Mariam Atta Elmannan , Ali Nahla Osman Mohamed 
Published: April 2020

Mosquitoes are a large diverse group of insects, with members being most important as vectors of diseases. The correct identification of mosquitoes is crucial to the control of the mosquito-borne diseases. This study was designed to provide baseline data on the species composition and distribution of members of the Anophelines and Culicines genera in ten selected localities in Kosti region, White Nile State, Central Sudan. Global Positioning System (GPS) was used to select collection sites. Adult mosquitoes were collected by pyrethrum spray catch (PSC) from randomly selected houses in Allia, Alnsr, Alskahdeed, Almrabie, Alshati, Althwrat, Alraba, Block 26, Block 32 and Khadugli in Kosti region during September 2014-August 2015. The Anophelines and Culicines mosquitoes were identified using standard morphological keys. Two Anopheles species and three Culex species were morphologically identified. These were An. gambiae s.s.; An. pharoensis; Cx. quinquefasciatus; Cx. univittatus and Cx. pipiens. This is the first report of An. pharoensis in the study area. The Highest mosquito abundance was observed in the September followed by October, while the lowest mosquito abundance was in July. An. gambiae s.s and Cx. quinquefasciatus were the predominant species which has importance as they indicate the presence of Malaria and arboviral infections in the study areas; respectively. These findings are of importance in the planning and implementation of vector control strategy in the Kosti region, White Nile state.
The status, challenges and opportunities of civil registration and vital statistics in Ethiopia: a systematic review
Authors: Gizaw Muluneh E. 
Published: April 2020

<p>While civil registration and vital statistics (CRVS) plays prominent roles to improve public sector management, i.e., the economic, social and political issues of a population, its adoption has not been yet without challenges and is still in its infant stage in most developing countries, including Ethiopia. This study reviews various literatures and studies made by different researchers and institutions related to the status, challenges and opportunities of CRVS in Ethiopia. Even though, CRVS has got a national recognition before hundred years in the country, the directives and rules are not issued for implementation. According to the findings,<strong> </strong>Ethiopia is among the countries that have not yet installed CRVS systems in both national and regional levels successfully. It is challenged by infrastructure, capacity building and lack of awareness among the population on the benefits of the system. The status of civil registration and vital statistics is in the lowest rank in Ethiopia. Recently, the aid agencies and the government has been giving special attention to scale up its performance in different parts of the country.</p><p> </p>
Study of clinico-epidemiological profile of leprosy patients at tertiary care centre of South Gujarat region
Authors: Patel Kautuk K. , Momin Anjum M. , Mistry Ankita A. , Vaishnani Jignesh B. 
Published: April 2020

<p class="abstract"><strong>Background:</strong> Leprosy is a chronic feared illness causes by <em>Mycobacterium leprae</em>. It was eliminated as a public health problem in India in 2005. But still, India contributes more than 60% of all new cases of leprosy.</p><p class="abstract"><strong>Methods:</strong> A retrospective analysis of 307 patients attending the leprosy clinic of the dermatology out patient department, SMIMER, was done for a period of five years from January 2014 to December 2018. The data was analysed for clinical and epidemiological characteristics of the patients.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 307 patients visited the leprosy clinic during the study period. More than half patients (60.3%) were between 21-40 years age group. There were 213 males and 94 females with male female ratio of 2.3:1. 72.3% (222) patients were suffering from multibacillary leprosy and 27.7% (85) had paucibacillary disease. Borderline tuberculoid leprosy was the most common type found in 83 patients (27.1%). 16 cases (5.2%) of childhood leprosy (less than 14 years of age) were noted. A total of 214 patients (69.7%) were migrants.</p><p class="abstract"><strong>Conclusions:</strong> Despite of decline at global and national level, leprosy cases show gradual increase. The high proportion of total cases, MB cases, and grade 2 disability cases are warning signs. Continued efforts are required to manage and prevent the disease.</p><p class="abstract"> </p>
A localized non-healing ulcer: an unusual clinical presentation of pemphigus vulgaris
Authors: Brar Sukhmani K. , Bhale Gauri N. , Brar Balvinder K. 
Published: April 2020

<p>Pemphigus vulgaris is an autoimmune blistering disorder commonly involving oral mucosa and skin<strong> </strong>with characteristic acantholysis that results in formation of fluid filled blisters and painful erosions. Herein we report a case distinguished by its unusual clinical presentation.<strong> </strong>A twenty-five year old man, presented to our outpatient department of dermatology, complaining of ulcer on forehead in the last one year. Examination revealed single ulcer covered with crust on right side of forehead. Clinically lupus vulgaris, pyoderma gangrenosum, recurrent herpes simplex, leishmaniasis and pemphigus vulgaris were kept as differential diagnosis. Tzanck smear revealed multiple acantholytic cells and mild neutrophilic inflammatory infiltrate. Histological examination of biopsy sample showed suprabasal clefting, acantholytic cells and mild perivascular dermal lymphocytic infiltrate. Features were suggestive of pemphigus vulgaris. Significant improvement occurred after three months of treatment with oral prednisolone, azathioprine and topical steroid. Although oral and skin involve­ment is common, in the form of flaccid blisters and erosions, but non healing ulcer is unusual. This may represent a period of limited activity during this chronic disease. There is paucity of data in literature regarding this. So, this<strong> </strong>case report highlights a, perhaps unique, clinical presentation of this autoimmune disease.<strong></strong></p>