bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prostatectomía radical asistida por robot en el Centro Médico Naval. Experiencia inicial
Authors: Soto-Vázquez Teresita , Almeida-Magaña Ricardo , Villeda-Sandoval Christian Isaac 
Published: December 2020

Introducción: La prostatectomía radical asistida por robot (RARP) es cada vez más utilizada alrededor del mundo. En México existen 13 hospitales que cuentan con equipo de cirugía robótica. En otros países ha demostrado disminuir la morbilidad quirúrgica con la misma efectividad en resultados oncológicos y funcionales.
Objetivo: Reportar los resultados de experiencia inicial y seguimiento a corto plazo de RARP en el Centro Médico Naval.
Material y métodos: Se realizó una revisión retrospectiva de los pacientes sometidos a RARP en nuestra unidad del 19 marzo 2016 al 30 abril 2018 que cumplieran con al menos 6 meses de seguimiento postquirúrgico.
Resultados: Se realizaron 48 RARP, con una media de edad de 64,7 años, APE preoperatorio medio de 10,4ng/dl, con clasificación de riesgo bajo, intermedio y alto de 19, 29 y 52%. El tiempo quirúrgico medio fue de 240 minutos, sangrado medio 223 ml, 3 días de estancia hospitalaria. Se realizó neuropreservación al 56.3%, y se realizó linfadenectomía estándar a 68.8 y extendida a 31.2%. Tasa de bordes positivos del 45.8%. Se reportó falla bioquímica en el 14.6%. Un 12.5% recibieron radioterapia externa postquirúrgica. El tiempo medio de seguimiento fue de 9 meses. Documentamos una tasa de continencia completa en 91,3% de los pacientes y función eréctil suficiente para sexo en el 53,5% de los pacientes.
Conclusiones: Reportamos resultados similares a los de la literatura mundial en morbilidad funcional y perioperatoria, en el inicio de nuestra curva de aprendizaje a pesar de tener una población con características de alto riesgo.
Uso de acetato de abiraterona en pacientes con cáncer de próstata metastásico resistente a la castración, vírgenes a quimioterapia. Experiencia de la vida real en un Centro Médico de la Ciudad de México
Authors: Alias-Melgar Alejandro , Cortéz-Betancourt Roberto , Suárez-Cuenca Juan Antonio , Ramírez-Garduño Emilio , Ordoñez-Campos Eduardo , Carreño-De la Rosa Fernando , Botello-Gómez Pedro , Camargo-Altamirano Leonardo , Sierra-Sosa José Gerardo , González-Serrano Adolfo , Trujillo-Vázquez Eric Iván , Pérez-Cabeza de Vaca Rebeca , Pineda-Juárez Juan Antonio , Mondragón-Terán Paul , Erazo-Valle Solís Aura Argentina 
Published: December 2020

Objetivo: Analizar la experiencia clínica con el acetato de abiraterona en pacientes con cáncer de próstata metastásico resistente a la castración (mCRPC, por sus siglas en inglés) vírgenes a quimioterapia, en un escenario de la vida real en un Centro Médico de la Ciudad de México.
Métodos. Estudio observacional en pacientes del Departamento de Urología, CMN "20 de Noviembre", ISSSTE; con mCRPC vírgenes a quimioterapia. Se administraron acetato de abiraterona más prednisona y leuprolida durante Enero de 2014 a Diciembre de 2016. Evaluación primaria: tiempo hasta la progresión radiológica y sobrevida. Evaluación secundaria (tiempo para progresión de ECOG, tiempo para inicio de quimioterapia citotóxica, tiempo para uso de analgésicos y tiempo para progresión del APE), en subgrupos divididos por el puntaje de Gleason.
Resultados. Dieciocho pacientes recibieron acetato de abiraterona. La progresión radiográfica se observó después de 7 y 10 meses (2 casos, 11.1%); y la muerte (1 caso, 5,5%) ocurrió después de 9 meses. El uso temprano de analgésicos fue frecuente (>50% a los 10 meses); mientras que la progresión de la enfermedad, reflejada por el inicio de la quimioterapia, la elevación del puntaje de ECOG y valores de APE, ocurrió en <50%. Además, observamos una tendencia a un inicio más temprano de la quimioterapia, la progresión de ECOG y el uso de analgésicos si el puntaje de Gleason era >7. Trece (72.2%) pacientes mostraron eventos adversos como fatiga, dolor de espalda, sofocos y otros; ninguno de ellos fue fatal.
Conclusión. El uso de acetato de abiraterona resultó tan eficaz y seguro en un escenario del mundo real en la muestra estudiada, como en los reportes previos de la literatura; por lo que puede ser una opción terapéutica valiosa en poblaciones similares.
Tumores de vejiga no uroteliales , como reto diagnóstico y terapéutico
Authors: Reyna-Blanco Irving , Jiménez-García Aldo , Martínez-Salas Alán De Jesús , Muruato-Araiza Jesús Sebastián , Herrerías-Ordoñez Andrea , Morales-Montor Gustavo , Martínez-Arroyo Carlos , Fernández-Noyola Gerardo , Cantellano-Orozco Mauricio , Pacheco-Gahbler Carlos 
Published: December 2020

Introducción: El cáncer de vejiga se clasifica en general como urotelial y no urotelial. El no urotelial representa menos del 5% de todos los tumores vesicales y de estos el 90% son de origen epitelial, incluyendo: carcinoma de células escamosas, de células pequeñas y adenocarcinoma. El 10% restante es de origen no epitelial (linfoma, paranganglioma, sarcoma, etc.).
Objetivo: Presentar la experiencia del cáncer de vejiga no urotelial y describir las características de los pacientes en nuestra institución.
Materiales y métodos: Estudio retrospectivo y descriptivo de expedientes de pacientes con cáncer vesical no urotelial, diagnosticados y tratados en nuestro servicio de 2004 al 2016, obteniendo 7 casos.
Resultados: 7 pacientes, 5 hombres y 2 mujeres. Edad 53 años (35-76). Síntomas principales hematuria 4, STUI 2 y mucosuria 1 . Histopatología: adenocarcinoma 3, carcinoma epidermoide 2, paraganglioma 1 y linfoma 1. Localización mas frecuente: domo vesical. Tratamiento: Adenocarcinoma (3): Cistectomía parcial 2, solo rtuv 1. Carcinoma epidermoide (2): 1 nefroureterectomía izquierda + cistoprostatectomía radical, 1 cistectomía radical + exenteración pélvica, ambos casos con RT adyuvante; Paraganglioma: 1 Cistectomía parcial laparoscópica asistida por robot, Linfoma: 1 rtuv + Quimioterapia + radioterapia. 2 defunciones por carcinoma epidermoide.
Discusión: Dada la poca frecuencia de estos casos es difícil la estandarización entre el tratamiento y la histopatología, pero en general la cirugía es la mejor opción terapéutica para evitar la recurrencia y mejorar supervivencia, en algunos casos se recomiendan terapias conservadoras de órgano con terapias adyuvantes personalizadas a la histopatología.
Conclusiones: El manejo de los tumores vesicales no uroteliales es complejo y requiere de un equipo multidisciplinario. Los tumores mas agresivos son epidermoides con alta posibilidad de extensión locorregional. La experiencia en México es limitada.
A General Model of Buddhism-Based Management
Authors: Takei Hideki 
Published: December 2020

Buddhism-based management has been popular among businesspersons. However, many studies about the business seemed subjective as authors used their values and interpretations of Buddhism (Weerasinghe, Thisera, and Kumara, 2014; Ashtankar, 2015; Shakya, 2017). We agree with Abe's (2007) conclusion that the absence of a generally accepted Buddhism-based business model is the leading cause. We need a general model. This paper suggests a generally accepted Buddhism-based business model by integrating all aspects of Buddhism-based business from published studies and the Buddha's original teachings. We will then use a Japanese Buddhism-based company, Warehouse TERRADA Co, to verify this model.
La pluralisation des espaces communautaires francophones en situation minoritaire : défis et opportunités pour l’intégration sociale et culturelle des immigrants
Authors: Veronis Luisa , Huot Suzanne 
Published: December 2020

Quelle est la nature changeante des espaces communautaires francophones à la lumière des politiques récentes mettant l’accent sur l’immigration francophone ? Nous répondons à cette question en nous basant sur les résultats d’une étude comparative des villes de London et d’Ottawa, en Ontario. Premièrement, nous constatons que le maintien et la vitalité de ces espaces semblent être à risque du fait de la situation de précarité qu’ils affrontent actuellement ; deuxièmement, nous soulignons le pluralisme croissant des espaces communautaires francophones dans ces deux villes ontariennes. De façon générale, nous traitons trois thèmes principaux : le rôle de ces espaces et les opportunités qu’ils peuvent offrir, des enjeux d’invisibilité communautaire et les défis liés au maintien de ces espaces.
Mouvements migratoires pendulaires, trajectoires professionnelles et liens familiaux : le cas de la Nouvelle-Écosse en sourdine
Authors: Fontaine Louise 
Published: December 2020

Les migrations internationales, qui transforment les sociétés sur l’ensemble de la planète, ont engendré de nouveaux questionnements. En reliant migrations, impératifs économiques et liens familiaux et sociaux, qu’observe-t-on ? Quelles sont les incidences de ces facteurs dans la société néo-écossaise ? Et plus particulièrement, que peut-on dégager en isolant le critère linguistique en contexte minoritaire francophone ? Cette note de recherche soulève des questions et explore des théories et des méthodes de recherche en les liant à un travail de terrain déjà réalisé et à venir.
Distinctive plumage patterns enable individual recognition of the Australian Magpie Cracticus tibicen
Authors: Kuruppu Ishini K. , Saunders Denis A. 
Published: December 2020

ABSTRACT
We investigated whether the plumage patterns of the Australian Magpie Cracticus tibicen, a medium-sized, black and white bird, common over most of mainland Australia and Tasmania, including cities and towns, were sufficiently different and distinctive to allow humans to identify individual birds. Eighty participants took part in our pattern matching experiment to see how many of 10 photographs of individual birds they placed correctly below a panel showing 20 individual birds, each illustrated with three different photographs. Participants were from a range of ages, although the majority were high school students. All but two successfully matched some of the birds but there were considerable differences in accuracy and speed of performance. We tested differences in accuracy and time taken by participant, gender, age, and whether testing alone or testing at the same time as four other participants. We concluded that it is possible for humans to recognise individual Australian Magpies based on the birds’ plumage.
Antioxidant Capacity of Indigenous Root and Tuber Crops of Sri Lanka as Affected by Simple Processing
Authors: Rupasingha Poojanee , Ratnayake Kamani , Senarathne Anoma 
Published: December 2020

The indigenous root and tuber crops in Sri Lanka have not been exploited by the food industry. With a view to establish their nutritional importance and promote consumption and industry usage, this study determined the contents of selected bio active compounds and antioxidant properties in 15 root and tuber crops varieties namely, Amorphophallus paeoniifolius, Canna indica (2 Selections), Dioscorea alata (6 varieties), D. bulbifera, D. esculenta, Maranta arundinacea and Xanthosoma sagittifolium (3 varieties), both in their raw and processed (boiled) forms. Antioxidant capacity (AOC) of yams was determined by Ferric Reducing Antioxidant Power (FRAP) Assay and 2,2-diphenyl-1-picrylhydrazyl (DPPH) Radical Scavenging Assay. Total phenolics (TPC) and ascorbic acid contents (AAC) were determined by Folin-Ciocalteu method and 2,6-dichlorophenol indophenol visual titration method, respectively. Chemical analyses were performed on triplicate samples. The AOC in the raw form ranged from 56 mg TE/g dry weight (D. bulbifera) to 30 mg TE/g dry weight (M. arundinaceae) while it showed a 0.4% (D. alata ‘Raja ala’) to 45% (D. alata ‘Hingurala’) decrease when boiled. The TPC in the raw form was highest in D. bulbifera (190.5 GAE; mg/100 g) while it was lowest in D. esculenta (6 mg/100 g). Dioscorea alata ‘Jaffna Rasawalli’ showed the highest loss (95%) of phenolics when subjected to boiling. The Xanthosoma sagittifolium varieties ‘Kiri ala’ and ‘Isuru’ had the highest AAC (12 mg/100 mg) in raw form while it was lowest (2 mg/100 mg) in M. arundinaceae. D. bulbifera and X. sagittifolium ‘Kaha kiri ala’ retained relatively higher levels of antioxidants in their boiled forms. The contents of bioactive compounds in yams tended to decrease when subject to boiling. However, the degree of loss depended on the yam variety. Further research should focus on developing processing technologies to minimize the loss of bioactive compounds in root and tuber crops.
Participants’ Feedback about and Knowledge before and after a Two-Day Medical Humanities Workshop at Mysuru, India
Authors: Shankar Pathiyil Ravi , Kulkarni Praveen 
Published: December 2020

Background: Medical humanities is using subjects traditionally known as the humanities for specific purposes in education in medicine. A two-day medical humanities workshop was facilitated at JSS medical college, Mysuru, India on 9th and 10th March 2020.
Objectives: The authors obtained participant knowledge before and immediately post-conclusion of the workshop and their feedback regarding the workshop.
Methods: Participants’ knowledge was measured by asking them to answer true or false a set of twenty statements. Some statements were worded negatively, and their scores reversed when calculating the total score. Total scores pre and post-workshop were compared using appropriate statistical tests (p<0.05). Participant feedback about various facets of the workshop including venue, organization, facilitators, role-plays, activities related to paintings, home assignment, debate, and elicitation sessions were obtained. Free text comments were also invited.
Results: Thirty-four medical students (15 male and 19 female) participated. Most students were from Karnataka and the neighbouring Kerala state. The median total scores before and immediately following the workshop were 16.00 and 17.00. The increase was highly significant (p<0.001). The mean student ratings of all parameters were 3.8 and above. Role-plays and debates were the most enjoyable. A greater range of activities and more involvement of students from other institutions were suggested. A few other topics were recommended.
Conclusions: Participant feedback was positive. They wanted similar workshops in the future. The workshop could serve as a launchpad for a medical/health humanities module at the institution.
Inverse Lomax-Exponentiated G (IL-EG) Family of Distributions: Properties and Applications
Authors: Falgore Jamilu Yunusa , Doguwa Sani Ibrahim 
Published: December 2020

A new generator of continuous distributions called the Inverse Lomax-Exponentiated G family, which has three extra positive parameters is proposed. The structural properties of the new family that holds for any continuous baseline model including explicit density function expressions, moments, inequality measurements, moment generating function, reliability functions, Renyi and Shanon entropies, and distribution of order statistics are derived. A Monte Carlo simulation to test the efficiency of the maximum likelihood estimates is conducted. The application of the new sub-model to the two data sets using the maximum likelihood method indicates that the new model is better than the existing competitors.
Prevalence and Risk Factors of Infection with Soil Transmitted Helminths in Children from Bandjoun, the West Region of Cameroon
Authors: Nkouayep Vanessa Rosine , Nejsum Peter , Cleopas Dzune Fossouo Dirane , Nadia Noumedem Anangmo Christelle , Joël Atiokeng Tatang Rostand , Mbida Mpoame 
Published: December 2020

Background: Soil-transmitted helminths (STHs) continue to be a public health problem in developing countries. In Bandjoun, annual deworming is usually administered to school-age children through the national programme for the control of schistosomiasis and soil-transmitted helminthiasis in Cameroon. However, official data on the level of STH infections are scarce in this locality.
Methods: We investigated the prevalence and associated risk factors of STHs among children in Bandjoun with the intention to help design future intervention plans. We obtained demographic data and potential risk factors through the interview of children using a structured questionnaire. Stool samples from these children were collected and examined for helminth eggs using Willis’ technique.
Results: Three STHs were identified with an overall prevalence of 8.7%. These nematodes were Ascaris lumbricoides (8.3%), Trichuris trichiura (0.3%) and hookworms (Ancylostoma duodenale, Necator americanus) (0.7%). Failure to wash hands before meals (AOR: 2.152 [1.056-4.389]) was the main predictor associated with Ascaris infections. Not eating food picked up from the ground (AOR: 0.494 [0.261-0.937]) and not raising pigs at home (AOR: 0.109 [0.045-0.268]) reduced risk of infection.
Conclusion: We recommend that STHs control interventions in Bandjoun focus on the good management of domesticated pigs, the avoidance of contact with soil and handwashing from the earliest ages as a part of daily hygiene practice.
An Analysis of the Beef Production Industry and Marketing in Zambia
Authors: Sikamwaya Ray Munachoonga , Guiyu Zhao 
Published: December 2020

This paper studies and provide a comprehensive and critical research by analyzing and evaluating the beef marketing channels, determine marketing efficiency, examine key social and economic factors contributing to the success and failure and establish the regional market interactions across the three agro-ecological regions in Zambia.
To achieve this, the research used both primary and secondary qualitative and quantitative data from national representative surveys by Rural Agricultural Livelihood Surveys Reports which were implemented by Indaba Agricultural Policy Research Institute, and the 2017/18 Livestock and Aquaculture Census Report by Ministry of Fisheries and Livestock, Central Statistics Office, and other relevant literature related to this study. A questionnaire was used in primary data collection through snowball sampling technique, physically asking, and observing cattle farmers, abattoirs, wholesalers, processing companies and various players or actors in the beef market. Thereafter, intermediation theory was applied to develop a conceptual framework, transaction cost analysis was used to understand how and why different supply channels develop, and finally market performance was determined by analyzing the level of marketing margins.
It was found that there are two major channels (Channel A and Channel B used by small-scale and commercial scale farmers respectively) which have channel subdivisions and several social and economic factors influence the farmers choice of marketing channel as well as influence consumer choices. Channel A was dominated by intermediaries while channel B be was vertically integrated. It was determined that all beef channels in Zambia were efficient and three major consumer types were observed and the regional market interactions showed that region I supplies both II and III, region II supplies III while region III is more of a consumer region.
This study will help to fully understand cattle producers marketing channel selection, consumer choice of market and product quality, regional market interactions and develops recommendations making available valuable information to farmers, beef traders, companies, and policy makers thereby has the potential to improving beef trade and markets in Zambia.
Altered Multisegment Ankle and Foot Kinematics During Gait in Patients With Hypermobile Ehlers‐Danlos Syndrome/Hypermobility Spectrum Disorder: A Case–Control Study
Authors: Vermeulen Stefan , De Mits Sophie , De Ridder Roel , Calders Patrick , De Schepper Joris , Malfait Fransiska , Rombaut Lies 
Published: December 2020

ObjectiveAnkle‐foot problems have a considerable impact on daily functioning in patients with hypermobile Ehlers‐Danlos syndrome and hypermobility spectrum disorder (hEDS/HSD). Therefore, the objective of this study was to identify alterations in multisegment ankle and foot kinematics during gait and to assess foot function and pain in these patients.MethodsTwenty‐three women with hEDS/HSD and 23 healthy controls participated in this 3‐dimensional gait analysis. Multisegment ankle and foot kinematics were collected using the Ghent Foot Model and analyzed with Statistical Parametric Mapping. Foot function and pain were assessed using visual analog scale scores, the Margolis Pain Diagram, and the Foot Function Index.ResultsLevels of pain and foot dysfunction were significantly higher in subjects with hEDS/HSD (P < 0.001). Kinematic curve analyses provide evidence for a hypermobile first ray, represented by a significantly increased eversion position of the medial forefoot during stance phase (P < 0.001) in subjects with hEDS/HSD compared to controls. In addition, significantly more dorsiflexion was found in the medial and lateral forefoot and the rearfoot (P < 0.001). At the midfoot, an increased plantar flexion (P < 0.001) and at the level of the hallux a decreased dorsiflexion (P = 0.037) and increased inversion (P < 0.001) and abduction (P = 0.016) were found in subjects with hEDS/HSD.ConclusionThis study is the first to apply a multisegment foot model during gait in hEDS/HSD, which confirms the characteristic hypermobility throughout the foot, especially the hypermobile first ray.
Rituximab Versus Mycophenolate in the Treatment of Recalcitrant Connective Tissue Disease–Associated Interstitial Lung Disease
Authors: Zhu Lisa , Chung Melody P. , Gagne Laurence , Guo Haiwei H. , Guenther Zachary , Li Shufeng , Jacobs Susan , Morisset Julie , Mooney Joshua J. , Raj Rishi , Chung Lorinda 
Published: December 2020

ObjectiveInterstitial lung disease (ILD) is a major cause of morbidity and mortality in connective tissue diseases (CTDs). We aimed to assess the effect of rituximab ± mycophenolate mofetil (MMF) compared with MMF on pulmonary function and prednisone dosage in patients with CTD‐related ILD (CTD‐ILD).MethodsThis retrospective study included 83 patients from Stanford and Centre Hospitalier de l’Universite de Montreal. Fifteen patients received rituximab ± MMF (rituximab group), and 68 patients received MMF only (control group).ResultsMedian ILD duration at the start of treatment was longer in the rituximab group at 47 months (range: 4‐170) versus 6.5 months (range: 0‐164) in controls. Forced vital capacity (FVC) decreased by 3.0% (range: 11%‐21%) after treatment in the rituximab group, whereas it increased by 2.0% (range: 14%‐25%) in the control group (p = 0.025). Diffusing capacity of carbon monoxide (DLCO) decreased by 3.0% (range: 10%‐12%) after treatment in the rituximab group, whereas it increased by 4.5% (range: 30%‐36%) in the control group (p = 0.046). Mixed model analysis controlling for ILD duration, baseline DLCO, systemic sclerosis, pulmonary hypertension, and prednisone use showed no significant difference in FVC or DLCO between groups at 6 months or 1 year. The average daily prednisone dose score decreased after treatment in the rituximab group, whereas it remained unchanged in the control group (p = 0.017).ConclusionRituximab ± MMF did not significantly change pulmonary function compared with MMF alone, but it did result in a relative decrease in average daily prednisone dose in a population with recalcitrant CTD‐ILD.