bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adaptive Evolution of Peptide Inhibitors for Mutating SARS-CoV-2
Authors: Vukovic Lela , Han Yanxiao , Chaturvedi Parth , Kral Petr 
Published: July 2020

The SARS-CoV-2 virus is currently causing a worldwide pandemic with dramatic societal consequences for the humankind. In the last decades, disease outbreaks due to such zoonotic pathogens have appeared with an accelerated rate, which calls for an urgent development ofadaptive (smart) therapeutics. Here, we develop a computational strategy to adaptively evolve peptides that could selectively inhibit mutating S protein receptor binding domains (RBDs) of different SARS-CoV-2 viral strains from binding to their human host receptor, angiotensin-converting enzyme 2 (ACE2). Starting from suitable peptide templates, based on selected ACE2 segments (natural RBD binder), we gradually modify the templates by random mutations, while retaining those mutations that maximize their RBD-binding free energies. In this adaptive evolution, atomistic molecular dynamics simulations of the template-RBD complexes are iteratively perturbed by the peptide mutations, which are retained under favorable Monte Carlo decisions. The computational search will provide librariesof optimized therapeutics capable of reducing the SARS-CoV-2 infection on a global scale.
Safety Implications of GNSS Signal Interference at Zilina Airport
Authors: Andrej Novak  , Alena Novak Sedlackova  , Anna Stelmach  , Doris Novak  
Published: July 2020

The paper deals with the issue of GNSS interference and its subsequent impact on airport approach procedures. It discusses the problem of GNSS signal interference and interference identification on a practical example of a small regional airport in Zilina, located close to the highway, through research aimed at its identification, a proposal for the location of a monitoring station and subsequent practical verification. The paper seeks to analyse and provide recommendations for enhancing safety and reliability in GNSS approaches. Given the need to develop the air transport, it is important to ensure the safety and continuity of service provision at small regional airports. The GNSS approach at airports with insufficiently equipped navigation infrastructure seems to be one of the most suitable. Introduction of the GNSS interference monitoring in the final instrument approach phase would increase the safety and reliability of the flight.
POSITIONS AND STABILITY OF LIBRATION POINTS IN THE CIRCULAR RESTRICTED THREE-BODY PROBLEM WHEN THE BIGGER PRIMARY IS RADIATING AND OBLATING
Authors: Tyokyaa K. R. , Atsue Tersoo 
Published: July 2020

This paper investigates the positions and stability of libration points in the framework of the circular restricted three-body problem for the systems: Luyten726-8 and HD98800. The position of the third body lie in the plane almost directly above and below the center of the oblate primary. It is found that radiations and oblateness of the primary have destabilizing effects; the presence of any one or more of the latter makes weak the stabilizing ability of the former, consequently the overall effect is that the range of stability of the libration points decreases. Considering the range of stability and instability, that is and , the libration points are respectively stable and unstable for HD98800 and Luyten 762-8 systems. Our results show that, all the roots are real, and for each set of values, there exist at least a positive real part and hence in the Lyapunov sense, the stability of the libration points are unstable for the systems HD98800 and Luyten 762-8.
EFFECT OF STORAGE MATERIALS ON THE PROXIMATE COMPOSITION OF TOMATO (Lycopersicon Esculentum) POWDER
Authors: OLADIPUPO RUKAYAT , Yusuf K. A. , Salawu G. 
Published: July 2020

The effect of storage materials on the quality of tomato powder was studied. Fresh, firm and matured red tomatoes were washed, sorted and sliced to a uniform thickness of 5mm. The sliced tomatoes were pre-treated by dipping in 1% calcium chloride (CaCl2) and 0.2% potassium metabislphite (KMS) solution for 10 minutes at room temperature. 200g each of the sample was dried at temperatures of 600C until equilibrium moisture content was attained. The dried tomatoes were ground into powder and stored in Black polyethylene [BPE], White polyethylene [WPE], and Laminated Aluminium Foil [LAF] pouches for 6 weeks. The moisture content, crude protein, crude fibre, fat, total ash, and vitamin C of the tomato powder were determined using the method prescribed by AOAC. The carotene contents were determined by HPLC. The proximate analysis was repeated after 2 weeks, 4 weeks and 6weeks of storage. There was an increase in moisture content and ash content after 6 weeks of storage while a decrease in value of protein, fat and vitamin C content occurred after the storage period. All the parameters measured were best retained by the laminated aluminium foil (LAF) compared to black polyethylene (BPE) and white polyethylene (WPE) packaging material for the entire period of the study.
DETERMINATION OF THE PROXIMATE AND MINERAL CONTENTS OF DESERT DATE KERNEL (BALANITES AEGYPTIACA LINN.) AND THE PHYSICAL AND CHEMICAL CHARACTERISTICS OF THE KERNEL OIL AVAILABLE IN KANO STATE, NIGERIA
Authors: Datti Y. , Yahya A. T. , Koki I. B. , Lado U. A. , Musbahu L. , Shuaibu M. M. , Ahmad U. U. , Adamu G. A. , Umar A. , Nura T. 
Published: July 2020

The desert date (Balanites aegyptiaca) is one the most important relish trees found in many African countries. In this study the proximate and mineral compositions of the desert date kernel, as well as some of the physical and chemical properties of its oil were analyzed using standard procedures. The results of the proximate composition revealed the following mean concentrations: Moisture content 3.19%; ash content 2.89%; fat content 39.63%; crude protein content 33.75%; crude fiber content 13.06% and carbohydrate content 7.48%. And the mineral content revealed the following mean concentrations: Potassium 1.120 (mg/100g); calcium 0.390 (mg/100g); sodium 0.801 (mg/100g); magnesium 0.142 (mg/100g); iron 0.0024 (mg/100g); manganese 0.01512 (mg/100g); zinc 0.0082 (mg/100g); copper 0.00225 (mg/100g); nickel 0.00582 (mg/100g); cobalt 0.002623 (mg/100g) and chromium 0.003224 (mg/100g). While the results for the physical analysis of the kernel oil revealed the following: Color pale yellow; density g/cm3 0.910; specific gravity 0.907; refractive index 1.458 and viscosity 19.68. And on the other hand, the results for the chemical analysis of the kernel oil revealed the following: acid value 3.06 mgKOH/g; free fatty acid 1.27; peroxide value 3.71 mEq/Kg; saponification value 198 mg/KOH/g and iodine value 98.73 100/g. All the results were compared and found to be within the FAO/WHO standards. The seeds kernel of this plant was found to be high nutritional value, while its oil can be a good source of raw material for many oil-based products
Implementing Cost-effective Co-treatment of Domestic and Food-industrial Wastewater by Novel Methods for Estimating Industrial Load
Authors: Bakos Vince , Szombathy Péter , Simon József , Jobbágy Andrea 
Published: July 2020

Detection and characterization of hidden industrial inflows causing high fluctuations of the inlet load, is a challenging issue pushing plant operators for a cost-effective solution at regional wastewater treatment plants (WWTPs). On the other hand, carbon source of food industrial origin may have a good use at WWTPs facing otherwise inlet carbon source deficiency.In a case study of a regional domestic WWTP receiving seasonally organic carbon-rich discharge from a fruit juice factory, a new method combining on-site measurements and mathematical modelling was developed and successfully applied for estimating the quality and quantity of both industrial influent load and incoming domestic wastewater streams properly. The originally un-staged bioreactor system operated at low dissolved oxygen (low DO) concentration was unable to meet effluent nitrogen requirements with an additional constant risk of encouraging filament growth. A novel screening method based on special sampling campaigns for estimating carbon availability and C:N ratios of influent wastewater streams coming separately from the large catchment area, was developed and applied. Staging of the previously low DO basins into a flexible system containing non-aerated selectors proved to be efficient for enhancing both biological nitrogen removal and sculpturing appropriately settling biomass.
MENGUNGKAP FENOMENA BAHASA CAMPURAN PADA BUDAYA POPULER DALAM PERSPEKTIF POSTMODERN
Authors: Susanto Teguh Tri , Atmaja Jaka , Nurdiansyah Chepi , Alam Nur 
Published: July 2020

Globalisasi dengan pesatnya perkembangan teknologi informasi berdampak mencairnya batas sendi-sendi kehidupan manusia dalam banyak aspek. Salah satu aspek yang paling terdampak adalah kebudayaan. Masuknya budaya global meretas sekat-sekat budaya lokal. Dalam budaya global terjadi pencampuran aneka kebudayaan. Budaya hasil pencampuran tidak bisa lagi disamakan dengan budaya asal. Lahirnya model-model kebudayaan baru kadang-kadang mengejutkan dan sulit difahami. Salah satu unsur kebudayaan yang penting adalah bahasa. Di era tanpa batas ini marak digunakan bahasa campuran. Maraknya penggunaan bahasa campuran bisa dilihat pada budaya populer lirik lagu. Lagu bisa dimaknai sebagai bentuk media komunikasi sekaligus produk budaya. Sebagai unsur kebudayaan bahasa mampu merepresentasikan perubahan-perubahan sosial yang terjadi di tengah-tengah masyarakat penggunanya. Penggunaan bahasa campuran pada lirik lagu menarik untuk diteliti sebagai pintu masuk bagi kajian lebih jauh atas dinamika sosial budaya masyarakat. Pendekatan culture studies dengan perspektif kritis posmodern menggunakan metode analisis wacana menjadi pisau bedah yang digunakan untuk mengungkap hal-hal apa yang menjadi latar, motif atau ideologi penggunaan bahasa campuran dalam lirik lagu. Dari penelitian ini bisa difahami adanya pergulatan budaya antara budaya “superior” terhadap budaya inferior. Dominasi dan hegemoni terjadi secara simbolik yang mana hal tersebut bisa jadi merupakan bahaya laten bagi harmoni dalam keragaman budaya yang ada.
Effect of Effleurage Massage to Pain Intensity of First Stage Labor in Inpartu Mothers at Linez Clinic of Gunungsitoli in 2018
Authors: Saragih Hanna Sriyanti 
Published: July 2020

Pain in labor is a manifestation of the contraction (shortening) of the uterine muscle, and it was caused by stretching of the uterine and cervical segments as well as the presence of uterine muscle ischemia. According to WHO (World Health Organization) in 2015, it was estimated that every year 830 women died from complications of pregnancy and childbirth. One method that was very effective in dealing with pain is effleurage massage which was massage technique using the palms of the fingers with a circular motion pattern on the abdomen, waist or thighs. The purpose of this study was to determine the effect of effleurage massage on the intensity of first-stage labor pain in maternal mothers at Linez clinic of Gunungsitoli in 2018.
This type of research was guasy Experiment research design with non equivalent control group design. In this design, the grouping of sample members in experimental group and the control group was not random, using wilcoxon test. The population in this study were mothers in first pregnancy as many as 52 people, with a total sample of 20 experimental groups and 20 control groups. The data used were primary data using observation sheets.
From the research results, obtained p value 0.0001, it can be concluded that there was significant effect between experimental group and control group. It was hoped that midwives will update their midwifery service and practices such as participating in the latest midwifery training, so that they can increase their knowledge and apply it when conducting childbirth care as effort to reduce labor pain.
Keywords: Effluerage Massage, Pain Intensity of First Stage Labor
HUBUNGAN PERSEPSI AKSEPTOR KB DENGAN PEMILIHAN MKJP DI KELURAHAN TAHTUL YAMAN KOTA JAMBI TAHUN 2017
Authors: Alami Triarsy , Diniyati Diniyati , Netty Indarmien 
Published: July 2020

Pertumbuhan penduduk di Indonesia berkisar antara 2,15% hingga 2,49% per tahun. Strategi dalam pelayanan kontrasepsi yang dikembangkan saat ini adalah menggalakkan pemakaian Metode Kontrasepsi Jangka Panjang (MKJP). Menurut Data Puskesmas Tahtul Yaman Kota Jambi jumlah akseptor KB IUD sebanyak 0 akseptor, Suntik 23 akseptor, Pil 384 akseptor, Kondom 293 akseptor, Implant 54 akseptor, MOP 0 akseptor dan MOW 0 akseptor. Cara kontrasepsi yang termasuk MKJP adalah IUD, Implant, MOW, dan MOP. Berdasarkan 10 akseptor yang menggunakan kontrasepsi pil dan suntik ditanyakan pada saat pengamilan data mengatakan tidak mau menggunakan IUD karena merasa takut, disamping itu belum mendapat izin suami. Dampak pemakaian pil atau pun suntikan yang dipakai selama lebih 2 tahun akan menimbulkan tekanan darah dan kenaikan berat badan (Sulistyawati, 2013 : 56).
Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional yang bertujuan untuk mengetahui hubungan persepsi akseptor KB dengan pemilihan MKJP di Kelurahan Tahtul Yaman, populasi seluruh akseptor KB di Kelurahan Tahtul Yaman sebanyak 754 akseptor, dengan jumlah sampel 90 responden dan sampel diambil dengan teknik simple random sampling. Penelitian dilakukan pada bulan Maret sampai Desember 2017 dan pengambilan sampel dilakukan pada tanggal 21 sampai 28 Agustus 2017 dengan menggunakan lembar pertanyaan (kuesioner), selanjutnya data dianalisis menggunakan analisis univariat dan bivariat.
Berdasarkan hasil penelitian diketahui sebagian responden (35,56%) menggunakan MKJP, sebagian (64,44%) responden menggunakan Non MKJP, sebagian (51,1%) responden memiliki persepsi kurang baik tentang pemilihan MKJP, sebagian (48,9%) responden memiliki persepsi baik tentang pemilihan MKJP dan hasil uji statistik diketahui bahwa p-value = 0,000 < 0,05, berarti ada hubungan yang bermakna antara persepsi dengan pemilihan MKJP.
Berdasarkan hasil penelitian masih ada ibu yang belum memakai KB MKJP. Disarankan kepada Kelurahan Tahtul Yaman untuk meminta staf puskesmas memberi penyuluhan lebih jelas lagi tentang pemakaian kontrasepsi khususnya IUD, Implan, dan sterilisasi laki-laki maupun perempuan dalam rangka meningkatkan pengetahuan dan persepsi Akseptor KB dalam pemilihan MKJP.
PENGARUH GAYA KEPEMIMPINAN TERHADAP KINERJA KARYAWAN PADA PERUSAHAAN UMUM PERCETAKAN NEGARA REPUBLIK INDONESIA CABANG SURAKARTA
Authors: Manurung Michael 
Published: July 2020

Penelitian ini bertujuan untuk menganalisis pengaruh gaya kepemimpinan terhadap kinerja karyawan pada Perusahaan Umum Percetakan Negara Republik Indonesia cabang Surakarta. Pengumpulan data dilakukan melalui penyebaran kuesioner, wawancara dan dilaksanakan pada 43 karyawan Perusahaan Umum Percetakan Negara Republik Indonesia cabang Surakarta. Analisis data pada penelitian ini menggunakan bantuan SPSS versi 23. Jumlah sampelnya diambil secara keseluruhan karena jumlah populasinya kurang dari 100 orang. Penelitian ini meliputi uji validitas dengan analisis faktor, uji reliabilitas dengan Alpha Cronbach, uji asumsi klasik, uji korelasi dan uji parsial untuk menguji dan membuktikan hipotesis penelitian. Hasil penelitian menunjukkan bahwa secara parsial variabel gaya kepemimpinan berpengaruh secara positif dan signifikan terhadap kinerja karyawan Perusahaan Umum Percetakan Negara Republik Indonesia cabang Surakarta sebesar 0,772, artinya gaya kepemimpinan benar-benar dapat meningkatkan kinerja karyawan Perusahaan Umum Percetakan Negara Republik Indonesia cabang Surakarta.
THE FIRST DESCRIPTION OF THE FEMALE EXTERNAL MORPHOLOGY OF BISETOCREAGRIS CHENI JIA, ZHAO &amp; ZHANG, 2010 (PSEUDOSCORPIONES, NEOBISIIDAE) FROM CHINA
Authors: Gao Zhizhong , Zhang Feng , Huang Dawei 
Published: July 2020

This paper gives the first description of the female external morphology of Bisetocreagris cheni Jia, Zhao & Zhang, 2010 (Pseudoscorpiones, Neobisiidae) from China.
Fungal literature records database of the Northern West Siberia (Russia)
Authors: Filippova Nina , Arefyev Stanislav , Zvyagina Elena , Kapitonov Vladimir , Makarova Tatiana , Mukhin Victor , Sedelnikova Nellya , Stavishenko Iraida , Shiryaev Anton , Tolpysheva Tatiana , Ryabitseva Natalia , Paukov Alexander 
Published: July 2020

Mycological research in the Northern part of West Siberia has now become sufficient for review and digitisation as over 460 scientific works have been completed mainly since the beginning of the 20th century. The history of research in the region started from isolated studies at the beginning of the 20th century, but regular and systematic research started from the 1970s. Over the following decades, several dozens of researchers have worked in the area, but the reported occurrences were scattered amongst a broad variety of publications, mainly hardly available. The great need in digitisation and accumulation of fungal records reported in published literature in a standardised regional database has now become evident. The «Fungal records database of the Northern West Siberia» (FuNWS) was initiated in 2016 according to contemporary biodiversity data standards (Darwin Core), to be compatible and accessible by the broad research community. The database has been supplemented ever since by the collective effort of specialists working in the area. According to the database summary report, there are 3358 fungal and fungus-like species revealed in the Northern West Siberia at present. The richest in species number classes are Agaricomycetes (60%) and Lecanoromycetes (33%) with a total of 25 classes represented. The FuNWS database was uploaded to Global Biodiversity Information Facility (GBIF) (Ygra State University Biological Collection publisher) on 11 November 2017 (earlier titled «Fungal Records Database of Yugra, FReDY») to provide open access to the data and its reusability (Filippova et al. 2020).
This publication summarises the results of the digitisation of literature-based occurrence records of fungi and fungus-like organisms initiated in the Northern part of West Siberia for the first time in the history of mycological research. The bibliography of regional mycological publications was created to include about 460 published works (Suppl. material 2). In total, about 140 literature sources were digitised and about 22000 occurrence records were integrated into the FuNWS database (Filippova et al. 2020).
Chemical constituents of the root wood of Erythrina sacleuxii and determination of the absolute configuration of suberectin
Authors: Ombito Japheth O. , Bojase Gomotsang , R.T. Majinda Runner , B.  Masesane Ishmael , Schüffler Anja , Pusch Stefan , Weber Carina , Opatz Till 
Published: July 2020

Phytochemical investigation on the root wood of Erythrina sacleuxii (Leguminosae) led to the isolation of nine secondary metabolites (1-9). Compound 1 was isolated from the genus Erythrina for the first time. The pure compounds were identified on the basis of comprehensive spectroscopic and spectrometric analyses, while their absolute configurations were determined based on chiroptical measurements. Compounds 5 and 6 showed weak antifungal activity against Pyricularia oryzae with MIC values of 20 µg/mL.

Bull. Chem. Soc. Ethiop. 2020, 34(1), 135-140.
DOI: https://dx.doi.org/10.4314/bcse.v34i1.12
Determination of the stability of osmium(IV) hexachloride ICP-OES standards in HCl acid matrix
Authors: T. Chiweshe Trevor , Atangana Abdon , Deysel Lore-Mari 
Published: July 2020

The ideal HCl concentration used in stabilizing osmium standards was investigated in this study. Additionally, mathematical models were tested to predict the decomposition rate of osmium standards at room temperature. Osmium(IV) hexachloride stock solutions stabilized in 7 and 15% HCl were used to assess the decomposition rate using ICP-OES. Several sets of calibration standards were prepared from the original stock solutions. The first calibration set was prepared with no additional HCl added to the final solutions and other sets with a total HCl acid concentration of 0.2, 0.4, 0.6, 1.0 and 1.5% v/v. Emission intensities were measured at 0, 24, 48, 72 and 96 hours. Standards with no additional HCl acid added kept at room temperature showed increase in emission intensities after 24 hours. These changes in emission intensities indicated chemical instability of osmium standards at low acid concentration levels. Standards stabilized in 1.0–1.5% HCl and refrigerated below 10 ⁰C showed consistent emission intensities and had a shelf life of up to 48 and 72 hours, respectively. Four mathematical models were tested to determine the decomposition rate of the osmium standard. The first used rate of change concept and the second a stochastic approach. Both failed to capture osmium decay. The third was based on non-local operators with power law kernel and was able to capture the decay at earlier, but not later stages. The fourth, based on non-local operators with non-singular kernel was able to capture earlier and later decay due to its crossover properties in waiting time distribution.

Bull. Chem. Soc. Ethiop. 2020, 34(1), 193-202.
DOI: https://dx.doi.org/10.4314/bcse.v34i1.18
Influence of NiO nano-flakes dispersion on the viscosity of lubricating oil
Authors: Sundaram C. Mathalai , Rajesh A. Vembathu , Sivaganesan V. 
Published: July 2020

Protecting interacting surfaces of mechanical systems against friction and wear have a wide range of industrial applications. Viscosity is the supreme property of any lubricant which overpowers viscous drag in hydro-dynamically lubricated mechanical systems. The dispersion stability of NiO-nanolubricants is achieved by ultrasonication technique. The detailed study of the viscosity of NiO nano-flakes dispersed in SN500 lubricants with weight fraction of 0.25-1.5% was performed in the temperature between 40-90 °C. The results show that increasing the weight fraction of NiO nano-flakes resulted in consistence viscosity increment. Further, the measured viscosity is compared with different concentration and temperature dependent theoretical models. On the basis on experimental viscosity data a theoretical correlation is recommended to predict the viscosity of NiO-nanolubricants with less than 5% margin of deviation.

Bull. Chem. Soc. Ethiop. 2020, 34(1), 203-214.
DOI: https://dx.doi.org/10.4314/bcse.v34i1.19