bluuebunny/crossref_metadata_2025_split huggingface dataset:
Let's Turn the Lights Off to Turn the Stars On
Authors: Pinto G. A. 
Published: June 2020

In this project, the causes and consequences of light pollution were discussed. The students concluded that light pollution is not only responsible for the “disappearance” of the starry sky in cities, but also a threat to living beings and a huge waste of energy. They also concluded that the measures to avoid light pollution are within the reach of citizens and municipalities and are based on the use of energy-efficient exterior lighting that directs light only downwards.Students shared their findings with the community and, at the same time, developed an interest in Astronomy, together with their families.
A Schoolyard to Play
Authors: Guerra H. , Cortes N. , Santos C. 
Published: June 2020

This is an entrepreneurship project that promotes awareness, as its main action is to make the school more appealing. Students have raised this problem and identified the main goal of improving the schoolyard spaces. Problems were surveyed and solutions presented, with the focus of intervention in green spaces, new paintings, and organization of leisure spaces. Contacts were initiated with different stakeholders, for the potential implementation of the solutions found in this project.
Atmosphere Control of a House
Authors: Madaleno I. , Branco S. 
Published: June 2020

The project consists of the prototype of a house, whose atmosphere is controlled automatically. Specific Aims of learning: studying the Arduíno board and sensors for collecting information, controlling and executing actions, knowing the language of programming needed, searching for solutions to the challenges using technological resources. With this project, the students got toknow better the functioning of some sensors and how to apply them in other contexts. And they realized the importance of home automation in people's lives.
Maker Club in Pre-School
Authors: Freitas L. , Ferrás A. , Vaz C. , Fernandes A. S. , Torres F. , Queirós M. I. , Pint M. B. 
Published: June 2020

The project allows pre-school children to develop the problematization of what they are learning and, in secondary school, students’ perspectives of cooperative in the development of scientific literacy. In this type of activity, children, with the help of high school students, deepen and consolidate behavioral values for life, thus enabling a positive change in their attitudes, in the way of believing, innovating, planning and persisting to conquer. Theactivities developed are accessible, both in approach and availability as well as in the cost of materials.
Ribeira da Lage, a Stream to Protect
Authors: Tomaz M. , Vidal S. , Lopes A. , Espinha A. , Barata C. , Parente G. , Coito J. , Gouveia L. 
Published: June 2020

The students started by identifying the most vulnerable ecosystems in the vicinity of the school. The stream Ribeira da Lage was identified and this ecosystem was characterized and the possible sources of pollution were surveyed. Macroinvertebrates were analyzed for subsequent determination of the BMWP (Biological Monitoring Working Party) index to assess water quality. After the research work, several contacts began with local entities and institutions (CMO, ITQB; Parish Council) to raise awareness and create measures to protect the assessed and monitored ecosystem.
Local Shops of Cantanhede Online Platform
Authors: Teixeira M. 
Published: June 2020

This project is an initiative of a group of students of the technical course in management and programming of computer systems, taught at the Technical School of Cantanhede, which will allow consumers, through the Internet, to discover micro and small companies of the city through web pages. The idea came about following the analysis that has been made to the increasing decline of traditional shops and markets because of the increasing of large shopping centers. The project's objectives are to promote trade and proximity services; counteract the trend of exclusive promotion of large commercial groups to digital platforms; and give visibility to small local shops, so that they are able to attract new customers. It should be noted that this project aims to be multidisciplinary and promote a culture of proximity between the localcommunity and the school community, benefiting responsible citizenship.
There is Science at Guadalupe
Authors: Figueiredo S. 
Published: June 2020

Our project seeks to disseminate science throughout the school community. 12th-grade students are building a scientific magazine and developing mini-projects, in small groups, which aim to stimulate the school community's interest in science and scientific discoveries. There are groups of students doing research and planning experiments. Other groups have establishedpartnerships with pre-school and 1st cycle classes so that, in a playful and fun way, interest in science grows more and earlier. The project started in October/November 2019 and, at this moment, we are still planning and devising strategies. In parallel, some of the mini-projects are already being implemented. In partnerships with the pre-school and 1st cycle classes, we have already started a scientific cooking project. We will also hold workshops on building terrariums, maintaining aquariums, and composting projects.
Vegetable Garden at School
Authors: Serra S. , Menezes S. , Afonso P. , Rosário I. , Santos J. 
Published: June 2020

This project began in 2018/2019 due to the interests shown by three classes of the 5th year. Through a brainstorm, we realized that the concern about the lack of green spaces was common to several students of the school. Thus, the vegetable garden would make the school greener and more open to the community. The space for construction was chosen and partnerships were created with the department of environmental management and transport of Odivelas (CMO), and the school parents association. We have privileged collaborative and interdisciplinary work to streamline various activities throughout the school year. The study ofsoil, seeds, autochthonous plants and pollinating insects was done with the help of class teachers and librarian teachers. The days of the native forest and the tree were celebrated with the planting of trees and the holding of a plant fair. At school and throughout the year students disseminated their project through informative posters, school radio and the school's website.
Prediction of repurposed drugs for treating lung injury in COVID-19
Authors: He Bing , Garmire Lana 
Published: June 2020

Background: Coronavirus disease (COVID-19) is an infectious disease discovered in 2019 and currently in outbreak across the world. Lung injury with severe respiratory failure is the leading cause of death in COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there still lacks efficient treatment for COVID-19 induced lung injury and acute respiratory failure. Methods: Inhibition of angiotensin-converting enzyme 2 (ACE2) caused by the spike protein of SARS-CoV-2 is the most plausible mechanism of lung injury in COVID-19. We performed drug repositioning analysis to identify drug candidates that reverse gene expression pattern in L1000 lung cell line HCC515 treated with ACE2 inhibitor. We confirmed these drug candidates by similar bioinformatics analysis using lung tissues from patients deceased from COVID-19. We further investigated deregulated genes and pathways related to lung injury, as well as the gene-pathway-drug candidate relationships. Results: We propose two candidate drugs, COL-3 (a chemically modified tetracycline) and CGP-60474 (a cyclin-dependent kinase inhibitor), for treating lung injuries in COVID-19. Further bioinformatics analysis shows that 12 significantly enriched pathways (P-value <0.05) overlap between HCC515 cells treated with ACE2 inhibitor and human COVID-19 patient lung tissues. These include signaling pathways known to be associated with lung injury such as TNF signaling, MAPK signaling and chemokine signaling pathways. All 12 pathways are targeted in COL-3 treated HCC515 cells, in which genes such as RHOA, RAC2, FAS, CDC42 have reduced expression. CGP-60474 shares 11 of 12 pathways with COL-3 and common target genes such as RHOA. It also uniquely targets other genes related to lung injury, such as CALR and MMP14. Conclusions: This study shows that ACE2 inhibition is likely part of the mechanisms leading to lung injury in COVID-19, and that compounds such as COL-3 and CGP-60474 have potential as repurposed drugs for its treatment.
Estimating the number of undetected COVID-19 cases among travellers from mainland China
Authors: Bhatia Sangeeta , Imai Natsuko , Cuomo-Dannenburg Gina , Baguelin Marc , Boonyasiri Adhiratha , Cori Anne , Cucunubá Zulma , Dorigatti Ilaria , FitzJohn Rich , Fu Han , Gaythorpe Katy , Ghani Azra , Hamlet Arran , Hinsley Wes , Laydon Daniel , Nedjati-Gilani Gemma , Okell Lucy , Riley Steven , Thompson Hayley , van Elsland Sabine , Volz Erik , Wang Haowei , Wang Yuanrong , Whittaker Charles , Xi Xiaoyue , Donnelly Christl A. , Ferguson Neil M. 
Published: June 2020

Background: Since the start of the COVID-19 epidemic in late 2019, there have been more than 152 affected regions and countries with over 110,000 confirmed cases outside mainland China. Methods: We analysed COVID-19 cases among travellers from mainland China to different regions and countries, comparing the region- and country-specific rates of detected and confirmed cases per flight volume to estimate the relative sensitivity of surveillance in different regions and countries. Results: Although travel restrictions from Wuhan City and other cities across China may have reduced the absolute number of travellers to and from China, we estimated that more than two thirds (70%, 95% CI: 54% - 80%, compared to Singapore; 75%, 95% CI: 66% - 82%, compared to multiple countries) of cases exported from mainland China have remained undetected. Conclusions: These undetected cases potentially resulted in multiple chains of human-to-human transmission outside mainland China.
New technologies to improve healthcare in low- and middle-income countries: Global Grand Challenges satellite event, Oxford University Clinical Research Unit, Ho Chi Minh City, 17th-18th September 2019
Authors: Ngoc Dinh Minh , Nygate Joseph , Hoang Minh Tu Van , Thwaites C. Louise ,   Global Grand Challenges Event Vietnam Group
Published: June 2020

We report the outputs of a satellite event in Ho Chi Minh City, Vietnam, organized as part of the “2nd Global Grand Challenges of Engineering Summit”. The event considered challenges and potential solutions for improving low- and middle-income country (LMIC) healthcare systems, with particular reference to critical care. Participants from key regional and local stakeholders in healthcare and engineering discussed how new advances in technology, especially in the field of Artificial Intelligence, could be of potential benefit. This article summarizes the perspectives and conclusions of a group of key stakeholders from LMICs across South and South East Asia.
Not in the Job Description: The Commercial Activities of Academic Scientists and Engineers
Authors: Cohen Wesley M. , Sauermann Henry , Stephan Paula 
Published: June 2020

Scholarly work seeking to understand academics’ commercial activities often draws on abstract notions of the academic reward system and the representative scientist. Few scholars have examined whether and how scientists’ motives to engage in commercial activities differ across fields. Similarly, efforts to understand academics’ choices have focused on three self-interested motives—recognition, challenge, and money—ignoring the potential role of the desire to have an impact on others. Using panel data for a national sample of over 2,000 academics employed at U.S. institutions, we examine how the four motives are related to commercial activity measured by patenting. We find that all four motives are correlated with patenting, but these relationships differ systematically between the life sciences, physical sciences, and engineering. These field differences are consistent with differences across fields in the rewards from commercial activities as well as in the degree of overlap between traditional and commercializable research, which affects the opportunity costs of time spent away from “traditional” academic work. We discuss potential implications for policy makers, administrators, and managers as well as for future research on the scientific enterprise. This paper was accepted by Toby Stuart, entrepreneurship and innovation.
Endoscopic tattooing for colorectal lesions: impact on quality of care and patient outcomes
Authors: Nahid MAK , Shrestha AK , Imtiaz MR , Basnyat PS 
Published: June 2020

Introduction The National Bowel Cancer Screening Programme guidelines advocate the use of endoscopic tattooing for suspected malignant lesions to assist identification and to facilitate laparoscopic resections. However, endoscopic tattooing practices are variable in endoscopic units, resulting in repeat endoscopy and delay in patient management. The aim of this study was to assess the adherence to tattoo protocol for significant colonic lesions at an endoscopy unit in a large district general hospital. Materials and methods Prospectively collected data were analysed for 252 patients with significant colonic lesions between January 2017 and December 2018. Data were collected through reviewing patient’s notes, histopathology findings and endoscopy reports. Data on lesions, complications, number and site of tattoo placed, and any repeat endoscopy for a tattoo were collected. Results Of the 252 patients, 88% (n = 222) had malignant and 12% (n = 30) had benign lesions. Only 58.7% (n = 148) of those patients who had colonoscopy had tattoo placement reported. Of these 148 cases, the report stated the distance of tattoo in relation to the lesion in only 46% (n = 68) of patients. Unfortunately, 14.3% (n = 36) of patients required repeat endoscopy to tattoo the lesions prior to surgery. Conclusions Our study highlights the lack of uniformity of tattoo practice among endoscopists. Despite the National Bowel Cancer Screening Programme guidelines, a significant proportion of colorectal lesions are still not tattooed during their first endoscopy. Some patients had to have repeat endoscopy just for the purpose of tattooing. Active involvement and participation of all endoscopists in the colorectal and the complex polyp multidisciplinary teams may help to improve the tattoo service.
A review of the use of biological mesh products in modern UK surgical practice: a religious and cultural perspective
Authors: Koshy RM , Kane EG , Grocock C 
Published: June 2020

Introduction The UK is an increasingly multicultural society. This change coincides with an increasing use of animal products in medicine and surgery and a change in the UK law of consent. The refusal of Jehovah’s Witnesses to accept blood products is well known, but the use of animal products in surgery is a neglected topic. As society becomes more diverse and medicine becomes ever more advanced, there is increasing potential for a mismatch between what is medically possible and what is acceptable from a religious perspective. Methods Surgical products were identified by searching the literature and contacting manufacturing companies. Literature was identified by using PubMed and OVID (MEDLINE). Religious views were established by contacting national bodies for each group. Findings The views of common UK religious groups and the constituent parts of biological meshes are summarised in tables intended to be used as a reference during clinical practice. On an elective basis, the Islamic, Hindu. Sikh and Jain leaders contacted had strong views on avoiding animal derived products. The Christian and Jewish leaders contacted did not. All religious leaders contacted accepted the use of mesh derived from human tissue. All products, including those of porcine and bovine origin, were acceptable to all leaders contacted if the procedure was performed to save life. The highlighting of this issue should prompt earlier consideration and discussion in the surgical planning and the consenting process with all final decisions taken by both the surgeon and the individual patient.
Dual-band passband terahertz filter based on multilayer metamaterial
Authors: Li Jiu-sheng 
Published: June 2020

We have theoretically verified the design of dual-band passband terahertz filter using multilayer metamaterial. The top and bottom layers are composed of periodically branching structure metallic patterns, which are exactly the same. The middle layer consists of a periodically metallic square aperture. The three metallic layers are separated by two thin dielectric layers. An equivalent circuit model is used to simplify the design procedure of the proposed structure. The performance of the terahertz filter is analyzed via equivalent circuit model together with the full wave CST method. The results show that the proposed structure provides two passbands. One is the center frequency of 0.32 THz with

−

3

d
B

bandwidth of 164 GHz, and the other is the center frequency of 0.74 THz with

−

3

d
B

bandwidth of 176 GHz.
Tunable continuous-wave laser operation of Tm3+:BaY2F8 near 2.3  µm
Authors: Muti Abdullah , Baylam Isınsu , Tonelli Mauro , Sennaroglu Alphan 
Published: June 2020

We report, for the first time to our knowledge, tunable continuous-wave laser action in the

T
m

3
+

:

B
a
Y

2

F

8

(BYF) crystal near 2.3 µm. In the experiments, a BYF crystal doped with 3 at. % thulium was end pumped with a narrow-linewidth, tunable

T
i

3
+

:

s
a
p
p
h
i
r
e

laser with up to 920 mW of incident power. Lasing was achieved for the two pump polarizations of

E

/

/

x

and

E

/

/

y

. The best power performance was obtained in the case of

E

/

/

x

, double-end pumping, where 100 mW of output power was obtained at 2290 nm with 920 mW of pump power and 1% output coupler. The laser could be continuously tuned from 2233 to 2385 nm. Excitation spectra for

E

/

/

x

and

E

/

/

y

pumping were measured in the 760–810 nm range, and the optimum pumping wavelength was determined to be 779 nm for

E

/

/

x

. By using the lifetime and lasing threshold data, the stimulated emission cross section at 2290 nm was further determined to be

(

0.66

±
0.06
)
×

10

−
24

m

2

.
Ultracompact fiber all-optical router using a photo-controlled microbubble
Authors: Cao Kunjian , Liu Yi , Lang Changpeng , Xu Qinfeng , Zhao Yuan 
Published: June 2020

An ultracompact fiber router based on a photo-controlled microbubble was proposed in this Letter. Because the microbubble can be repositioned precisely in the fiber microcavity by adjusting the drive laser power, the target light beam that was incident on the gas-liquid interface of the microbubble was routed toward different directions by the light refraction inside the photo-controlled microbubble. Experimental results showed that the device had a low insertion loss of 0.64 dB, response time of (

1.2

−

1.8

s

), and can achieve the continuous beam redirections within an angle range of 56° by exploiting a drive laser power of only 1.8 mW. With the characteristics of excellent controllability, low consumption, and no electromechanical parts, such a fiber all-optical router has potential to be used for the multiplex treatments and analysis applications of the photonic laboratory on a chip (PLOC).
Comunicação, educação e vigilância popular em saúde em tempos de COVID-19 – a experiência das comunidades de Niterói, RJ
Authors: Latgé Paula Kwamme , Araújo Daniela Nunes , Silva Júnior Aluísio Gomes da 
Published: June 2020

O acesso à internet, renda mínima e à segurança alimentar no contexto do coronavírus (COVID-19) evidenciam a fragilidade social. Neste contexto, um grupo de jovens comunicadores da cidade de Niterói no Rio de Janeiro foi mobilizado pela OSC BemTV Educação e Comunicação para compor um capaz de enfrentar as dificuldades de acesso à internet e construir coletivamente a checagem de informações, combate a notícias falsas, capilarização do acesso e fortalecimento das políticas e estratégias para conter a exponencialidade da contaminação comunitária.
Effect of lncRNA KCNQ1OT1 on autophagy and drug resistance of hepatocellular carcinoma cells by targeting miR-338-3p
Authors: Zhong Weiwei , Dai Qianqian , Huang Qionghui 
Published: June 2020

The current experiment aimed to investigate the effects of lncRNA KCNQ1OT1 on the proliferation, autophagy and drug resistance of hepatocellular carcinoma cells, as well as the potential molecular mechanism. Hepatocellular carcinoma SK-HEP-1 cells and DDP resistant SK-HEP-1/DDP cells were treated with cisplatin (DDP) of different concentrations (1 nmol/L, 2 nmol/L, 4 nmol/L, 8 nmol/L, 16 nmol/L). The survival rate of SK-HEP-1 and SK-HEP-1/DDP cells was determined by the CCK8 method. QRT-PCR was used to detect the levels of lncRNA KCNQ1OT1 and miR-338-3p in normal hepatocyte HH01, hepatocellular cell SK-HEP-1 and hepatoma cisplatin-resistant cell SK-HEP-1/DDP. Western blot was carried out to detect the expression levels of autophagy-related protein Beclin1 and proliferation-related protein P21 in cells. A dual-luciferase reporter assay system was performed to validate the relationship between KCNQ1OT1 and miR-338-3p. After the treatment of 1 nmol/L, 2 nmol/L, 4nmol/L, 8nmol/L and 16nmol/L cisplatin (DDP), the survival rate of SK-HEP-1/DDP cells is higher than that of SK-HEP-1 cells. The level of lncRNA KCNQ1OT1 was increased successively in HH01, SK-HEP-1 and SK-HEP-1/DDP cells, while miR-338-3p was decreased successively. Silencing lncRNA KCNQ1OT1 or over-expressing miR-338-3p combined with 16nmol/L DDP treatment reduced the survival rate of SK-HEP-1/DDP cells and up-regulate levels of P21 and Beclin1 proteins. LncRNA KCNQ1OT1 targeted and negatively regulated the expression of miR-338-3p. Inhibition of miR-338-3p reversed the effect of silencing lncRNA KCNQ1OT1 on survival, autophagy and cisplatin sensitivity of SK-HEP-1/DDP cell. LncRNA KCNQ1OT1 targets miR-338-3p to regulate the survival rate and autophagy of SK-HEP-1/DDP cells and improve the cisplatin sensitivity of SK-HEP-1/DDP cells. LncRNA KCNQ1OT1 is a potential molecular target for hepatocellular carcinoma.
The Gender-bias Effect of Test Scoring and Framing: A Concern for Personnel Selection and College Admission
Authors: Espinosa Maria Paz , Gardeazabal Javier 
Published: June 2020

Abstract
This paper analyzes gender differences in student performance in Multiple-Choice Tests (MCT). We report evidence from a field experiment suggesting that, when MCT use a correction for guessing formula to obtain test scores, on average women tend to omit more items, get less correct answers and lower grades than men. We find that the gender difference in average test scores is concentrated at the upper tail of the distribution of scores. In addition, gender differences strongly depend on the framing of the scoring rule.
Electronic structural properties of amino/hydroxyl functionalized imidazolium-based bromide ionic liquids
Authors: Hu Xiaoling , Jia Xingang , Su Kehe , Gu Xuefan 
Published: June 2020

AbstractElectronic structural properties of the three different imidazolium-based ionic liquids, namely, 1-butyl-3-methyl imidazolium bromide (C4mimBr), 1-(4-hydroxybutyl)-3-methylimidazolium bromide (C4OHmimBr), and 1-(4-aminobutyl)-3-methylimidazolium bromide (C4NH2mimBr), were investigated with density functional theory at the B3LYP/6-311++G(d,p) level. The conformations of the mentioned cations were fully studied first using CONFLEX 8.A program. The quantum theory of atoms in molecules was used to investigate the nature of intramolecular interactions. The counterpoise-corrected ion pairs binding energies were obtained at the same level of theory. Natural bond orbital analyses show that the largest intra-molecular interaction comes from the orbital overlap between n(N1) and π* (N4–C5) in the mentioned compounds. The energy levels of frontier molecular orbitals (FMOs) are displayed. The global quantum chemical descriptors are also calculated based on the energy values of FMOs.