bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface Electromyographic Biofeedback and the Effortful Swallow Exercise for Stroke-Related Dysphagia and in Healthy Ageing
Authors: Archer Sally K. , Smith Christina H. , Newham Di J. 
Published: May 2020

AbstractDysphagia is common after stroke, leading to adverse outcome. The Effortful Swallow (ES) is recommended to improve swallowing but it is not known if dysphagic patients can increase muscle activity during the exercise or if age affects performance. Providing surface electromyographic (sEMG) biofeedback during dysphagia therapy may enhance exercise completion, but this has not been investigated and the technique’s acceptability to patients is not known. Aims: To determine if age or post-stroke dysphagia affect the ability to increase submental muscle activity during the ES, if sEMG biofeedback improves ES performance and if sEMG is an acceptable addition to therapy. In a Phase I study submental sEMG amplitudes were measured from 15 people with dysphagia < 3 months post-stroke and 85 healthy participants aged 18–89 years during swallowing (NS) and when they performed the ES with and without sEMG biofeedback. Participant feedback was collected via questionnaire. Measurements were compared with repeated measures ANOVA and age effects were examined with linear regression. Both groups produced significantly greater muscle activity for the ES than NS (p < 0.001) and significantly increased activity with biofeedback (p < 0.001) with no effect of age. Participant feedback about sEMG was very positive; over 98% would be happy to use it regularly. The ES is a physiologically beneficial dysphagia exercise, increasing muscle activity during swallowing. sEMG biofeedback further enhances performance and is considered an acceptable technique by patients. These findings support the potential application of sEMG biofeedback and the ES in dysphagia therapy in stroke, justifying further investigation of patient outcome.
The relationship between monoaminergic gene expression, learning, and optimism in red junglefowl chicks
Authors: Boddington Robert , Gómez Dunlop Clara A. , Garnham Laura C. , Ryding Sara , Abbey-Lee Robin N. , Kreshchenko Anastasia , Løvlie Hanne 
Published: May 2020

AbstractIntra-species cognitive variation is commonly observed, but explanations for why individuals within a species differ in cognition are still understudied and not yet clear. Cognitive processes are likely influenced by genetic differences, with genes in the monoaminergic systems predicted to be important. To explore the potential role of these genes in association with individual variation in cognition, we exposed red junglefowl (Gallus gallus) chicks to behavioural assays measuring variation in learning (discriminative learning, reversal learning, and cognitive flexibility) and optimism (measured in a cognitive judgement bias test). Following this, we analysed prefrontal cortex gene expression of several dopaminergic and serotonergic genes in these chicks. Of our explored genes, serotonin receptor genes 5HT2A and 5HT2B, and dopaminergic receptor gene DRD1 were associated with measured behaviour. Chicks that had higher 5HT2A were less flexible in the reversal learning task, and chicks with higher 5HT2B also tended to be less cognitively flexible. Additionally, chicks with higher DRD1 were more optimistic, whilst chicks with higher 5HT2A tended to be less optimistic. These results suggest that the serotonergic and dopaminergic systems are linked to observed cognitive variation, and, thus, individual differences in cognition can be partially explained by variation in brain gene expression.
Exact distributional analysis of online algorithms with lookahead
Authors: Dunke Fabian , Nickel Stefan 
Published: May 2020

AbstractIn online optimization, input data is revealed sequentially. Optimization problems in practice often exhibit this type of information disclosure as opposed to standard offline optimization where all information is known in advance. We analyze the performance of algorithms for online optimization with lookahead using a holistic distributional approach. To this end, we first introduce the performance measurement method of counting distribution functions. Then, we derive analytical expressions for the counting distribution functions of the objective value and the performance ratio in elementary cases of the online bin packing and the online traveling salesman problem. For bin packing, we also establish a relation between algorithm processing and the Catalan numbers. The paper shows that an exact analysis is strongly interconnected to the combinatorial structure of the problem and algorithm under consideration. Results further indicate that the value of lookahead heavily relies on the problem itself. The analysis also shows that exact distributional analysis could be used in order to discover key effects and identify related root causes in relatively simple problem settings. These insights can then be transferred to the analysis of more complex settings where the introduced performance measurement approach has to be used on an approximative basis (e.g., in a simulation-based optimization).
Foliar P nutrition of European beech (Fagus sylvatica L.) depends on the season but remains unaffected by co-cultivation with silver fir (Abies alba Mill.)
Authors: Yang Fengli , Magh Ruth-Kristina , Ivanković Mladen , Lanšćak Miran , Haberstroh Simon , Du Baoguo , Dannenmann Michael , Rennenberg Heinz , Herschbach Cornelia 
Published: May 2020

AbstractBeech (Fagus sylvatica) and silver fir (Abies alba) are often cultivated in mixed stands and, hence, compete for water and nutrients. Besides nitrogen (N), also phosphorus (P) is an important nutrient for growth and development. Beech trees in Central Europe grow on both P-poor and P-rich soils, thereby showing similar growth and low variation in foliar P. The central aim of the present study was to test the hypothesis that variations in foliar P contents of beech are driven by seasonal changes rather than by the competition with silver fir. It was further hypothesized that P contents in silver fir needles depend on needle age and forest site. To test these hypotheses, P contents and P fractions, i.e. organic-bound P (Porg) and inorganic phosphate P (Pi), were measured in the foliage of beech trees from pure beech and mixed beech/silver fir plots as well as in needles of silver fir of the mixed plots. The forest sites investigated are located in Central Europe in the Black Forest, Germany, and in Croatia near the south-eastern distribution limit of beech and are all poor in plant-available soil P. The analyses showed that the main driver of P contents and P fractions in beech leaves at all forest sites is the season and that competition with silver fir had no effect. Hence, the present results demonstrate the high plasticity of beech trees to adapt to both poor plant-available soil P and competition with silver fir. Total P contents of silver fir needles were higher at the Croatian site compared to the Black Forest sites and originated from higher foliar Pi contents. One third of the P present in current-year needles in late summer was remobilized and exported until the needles reached the age of 1 year. The difference in P contents between current-year and 1-year-old needles can be seen as the amount of P resorbed from 1-year-old needles in summer during the generation of new needles to support the P demand of current-year needles for growth and development.
Scalar Effects in Ground Slate Technology and the Adaptive Consequences for Circumpolar Maritime Hunter-Gatherers
Authors: Jørgensen Erlend Kirkeng 
Published: May 2020

AbstractGround slate technology is a trademark of circumpolar hunter-gatherers occupying coastal ecotones. However, a causal framework for explaining what drives the apparent adaptive success of slate technology is lacking. Attempting to remedy this, the current paper provides the first palaeodemographic and environmentally informed review of a maritime slate complex. Employing what is arguably the best documented and contextually controlled slate industry in Holocene Eurasia as a high-resolution case study (the Arctic Norwegian slate industry), the system components of demography, ecology and technology are integrated to get at (1) why slate technology appears to be a particular maritime success, (2) what causal contribution slate technology makes to population-scale adaptive success, (3) why slate technology was eventually abandoned. Based on extensive empirical investigations, the results demonstrate synchronous changes in population size, maritime intensification and the use of slate technologies. It is suggested that the mechanism responsible for this correspondence is that the slate industry facilitated a heightened adaptive success, reinforcing population growth and maritime intensification. Technological results indicate that superior properties for standardization make the slate technology ideal for establishing a scale economy in maritime resource exploitation when surpassing critical thresholds in population packing. Causal modelling demonstrates that, under particular demographic and ecological conditions, the scalar properties of slate technologies can offset high- and density-dependent start-up costs, by increasing return rates and reducing handling costs of hunting/processing of marine resources. Satisfying all criteria for tool “efficiency”, it is concluded that slate industries have causal efficacy as an “enabling technology” in circumpolar, maritime settings.
An evaluation of percentile measures of citation impact, and a proposal for making them better
Authors: Bornmann Lutz , Williams Richard 
Published: May 2020

AbstractPercentiles are statistics pointing to the standing of a paper’s citation impact relative to other papers in a given citation distribution. Percentile Ranks (PRs) often play an important role in evaluating the impact of researchers, institutions, and similar lines of study. BecausePRs are so important for the assessment of scholarly impact, and because citations differ greatly across time and fields, various percentile approaches have been proposed to time- and field-normalize citations. Unfortunately, current popular methods often face significant problems in time- and field-normalization, including when papers are assigned to multiple fields or have been published by more than one unit (e.g., researchers or countries). They also face problems for estimating citation counts for pre-definedPRs (e.g., the 90thPR). We offer a series of guidelines and procedures that, we argue, address these problems and others and provide a superior means to make the use of percentile methods more accurate and informative. In particular, we introduce two approaches,CP-INandCP-EX, that should be preferred in bibliometric studies because they consider the complete citation distribution and can be accurately interpreted. Both approaches are based on cumulative frequencies in percentages (CPs). The paper further shows how bar graphs and beamplots can presentPRs in a more meaningful and accurate manner.
Detailed In Situ Hot Stage Transmission Electron Microscope Observations of the Localized Pinning of a Mobile Ferrite-Austenite Interface in a Fe-C-Mn Alloy by a Single Oxidic Particle
Authors: Nutter J. , Rainforth W. M. , van der Zwaag S. 
Published: May 2020

AbstractThe current study reports the detailed analysis of an observation of the local pinning of a slowly moving austenite-ferrite interface by a single nanosized oxidic particle. The observations were made during anin situcyclic partial phase transformation experiment on a Fe-0.1C-1.0Mn alloy close to the inversion stage at which the interface migrates at a rather low velocity. The low velocity allowed capturing the interface pinning effect over a period of no less than 16 seconds. From our observations, it was possible to follow the progression of the pinning effect from the initial stages all the way through to the release of the interface. The pinning force exerted by the individual particle having a diameter of 140 nm on the austenite-ferrite interface was estimated as 175 nJ m−1, while the maximum pinning length was approximately 750 nm to either side of the particle, leading to an interface line tension of 170 nJ m−1. The observed pinning behavior is compared with the most relevant models in the literature.
Cognitive Dysfunction in the Early Stages of Multiple Sclerosis—How Much and How Important?
Authors: Oset Magdalena , Stasiolek Mariusz , Matysiak Mariola 
Published: May 2020

Abstract
Purpose of Review
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that mainly affects young adults and that is one of the leading causes of disability in this age group, with cognitive impairment occurring early in the course of the disease. This article summarizes the current knowledge about cognitive dysfunction in the early phase of MS, including biomarkers, MRI correlates, and its value as a prognostic marker.

Recent Findings
New sets of neuropsychological tests have been established to screen for cognitive dysfunction more easily and accurately. Moreover, structural changes detected by brain MRI and several biomarkers found in cerebrospinal fluid and blood serum have been recently correlated with decreased cognitive performance. Additionally, factors influencing cognition in MS, such as disease-modifying therapy, mood disorders, and lifestyle, are better described.

Summary
Cognitive impairment early in the course of MS is suggested as a prognostic factor for disease progression. However, clear-cut definitions of the early stage of MS as well as unified criteria for the diagnosis of cognitive impairment are still lacking. New and more reliable tools for evaluating cognition in MS patients should be developed and introduced into everyday practice to facilitate the implementation of effective disease-modifying therapy, cognitive rehabilitation, and lifestyle management.
Analysis of the interaction between elderly people and a simulated virtual coach
Authors: Justo Raquel , Ben Letaifa Leila , Palmero Cristina , Gonzalez-Fraile Eduardo , Torp Johansen Anna , Vázquez Alain , Cordasco Gennaro , Schlögl Stephan , Fernández-Ruanova Begoña , Silva Micaela , Escalera Sergio , deVelasco Mikel , Tenorio-Laranga Joffre , Esposito Anna , Korsnes Maria , Torres M. Inés 
Published: May 2020

AbstractThe EMPATHIC project develops and validates new interaction paradigms for personalized virtual coaches (VC) to promote healthy and independent aging. To this end, the work presented in this paper is aimed to analyze the interaction between the EMPATHIC-VC and the users. One of the goals of the project is to ensure an end-user driven design, involving senior users from the beginning and during each phase of the project. Thus, the paper focuses on some sessions where the seniors carried out interactions with a Wizard of Oz driven, simulated system. A coaching strategy based on the GROW model was used throughout these sessions so as to guide interactions and engage the elderly with the goals of the project. In this interaction framework, both the human and the system behavior were analyzed. The way the wizard implements the GROW coaching strategy is a key aspect of the system behavior during the interaction. The language used by the virtual agent as well as his or her physical aspect are also important cues that were analyzed. Regarding the user behavior, the vocal communication provides information about the speaker’s emotional status, that is closely related to human behavior and which can be extracted from the speech and language analysis. In the same way, the analysis of the facial expression, gazes and gestures can provide information on the non verbal human communication even when the user is not talking. In addition, in order to engage senior users, their preferences and likes had to be considered. To this end, the effect of the VC on the users was gathered by means of direct questionnaires. These analyses have shown a positive and calm behavior of users when interacting with the simulated virtual coach as well as some difficulties of the system to develop the proposed coaching strategy.
Stress-based, statistical modeling of the induced seismicity at the Groningen gas field, The Netherlands
Authors: Richter Gudrun , Hainzl Sebastian , Dahm Torsten , Zöller Gert 
Published: May 2020

AbstractGroningen is the largest onshore gas field under production in Europe. The pressure depletion of the gas field started in 1963. In 1991, the first induced micro-earthquakes have been located at reservoir level with increasing rates in the following decades. Most of these events are of magnitude less than 2.0 and cannot be felt. However, maximum observed magnitudes continuously increased over the years until the largest, significant event with $$M_L=3.6$$ML=3.6 was recorded in 2014, which finally led to the decision to reduce the production. This causal sequence displays the crucial role of understanding and modeling the relation between production and induced seismicity for economic planing and hazard assessment. Here we test whether the induced seismicity related to gas exploration can be modeled by the statistical response of fault networks with rate-and-state-dependent frictional behavior. We use the long and complete local seismic catalog and additionally detailed information on production-induced changes at the reservoir level to test different seismicity models. Both the changes of the fluid pressure and of the reservoir compaction are tested as input to approximate the Coulomb stress changes. We find that the rate-and-state model with a constant tectonic background seismicity rate can reproduce the observed long delay of the seismicity onset. In contrast, so-called Coulomb failure models with instantaneous earthquake nucleation need to assume that all faults are initially far from a critical state of stress to explain the delay. Our rate-and-state model based on the fluid pore pressure fits the spatiotemporal pattern of the seismicity best, where the fit further improves by taking the fault density and orientation into account. Despite its simplicity with only three free parameters, the rate-and-state model can reproduce the main statistical features of the observed activity.
Contemporary use and trends in percutaneous coronary intervention in Japan: an outline of the J-PCI registry
Authors: Sawano Mitsuaki , Yamaji Kyohei , Kohsaka Shun , Inohara Taku , Numasawa Yohei , Ando Hirohiko , Iida Osamu , Shinke Toshiro , Ishii Hideki , Amano Tetsuya 
Published: May 2020

AbstractCardiovascular interventions have achieved a level of excellence, with many outstanding advanced techniques and results. The mission of the Japanese Association of Cardiovascular Intervention and Therapeutics (CVIT) is to further our understanding of cardiovascular intervention and establish its procedural safety. [1] The Japanese Percutaneous Coronary Intervention (J-PCI) registry was established and sponsored by CVIT, and aims to provide basic statistics on the performance of percutaneous coronary interventions (PCI) in Japan. Today, the database has grown to become one of the largest healthcare procedural database with more than 200,000 cases registered annually from approximately 900 institutions in Japan representing over 90% of all PCI hospitals in the nation. Importantly, case registrations in the J-PCI registry are essential for coronary interventionalist and educating hospital certification. The present manuscript aimed to summarize the history of the J-PCI registry and outline the definitions of various items.
Reservoir characterization for sweet spot detection using color transformation overlay scheme
Authors: Ismail Atif , Raza Arshad , Gholami Raoof , Rezaee Reza 
Published: May 2020

AbstractReservoir characterization carried out for the quantitative representation of a reservoir leads to effectively managing the hydrocarbon reservoir. There have been few attempts made to characterize the reservoir and assess the potential of a reservoir for the sweet spots using seismic, geomechanical, and petrophysical characteristics where a combination of seismic and petrophysical characters is often ignored given the complexity of such integration. To the best of our knowledge, none of the studies have provided overall reservoir characterization workflows using the combination of petrophysical and geomechanical attributes for sweet spot detection. This study aims to adopt a new color transformation overlay scheme to assess the potential of reservoirs by identifying the sweet spots that can guide to propose a location for a new well. The core scale measurements and well log interpretation were used to determine the petrophysical and geomechanical properties of a highly complex sandstone reservoir which were used as the input to build a 3D reservoir model. The results obtained indicated that predicting the distribution of sweet spots is an effective scheme for well-planning and field development in the region. Four sweet spots are identified in the studied reservoir based on the color transformation overlay approach which has heterogeneous continuity behavior in vertical and horizontal directions. The identification of sweet spots based on top view is not enough for the complete understanding of spreading in all directions. Cross-sectional analysis of the color transformation overlay model revealed that there is a sweet spot near Well-E in west which has ideal reservoir potential and place to consider another proposed well.
Does ORTO-15 produce valid data for ‘Orthorexia Nervosa’? A mixed-method examination of participants’ interpretations of the fifteen test items
Authors: Mitrofanova Elina , Pummell Elizabeth , Martinelli Laura , Petróczi Andrea 
Published: May 2020

Abstract
Purpose
Orthorexia Nervosa (ON) is defined as a pathological eating behaviour stemming from being “healthy” or “pure”. Survey-based studies typically rely on the ORTO-15 questionnaire or its variations to detect orthorexia. However, frequent post-hoc adjustments to the ORTO-15 suggest psychometric problems. In this study, we explored people’s cognitions about the ORTO-15 items to (1) identify problems specific to ORTO-15 items and (2) explore participants’ understanding of ON symptoms.

Methods
Fifty adult participants (40% male, mean age = 34.0 ± 14.4 years) completed the ORTO-15, the Eating Attitudes Test (EAT-26) and the Obsessive–Compulsive Inventory–Revised edition (OCI-R). Qualitative data were collected using the modified “think aloud” protocol, which asked participants to ‘verbalise’ their responses to the ORTO-15 items. These qualitative responses were first analysed conjunctively with the quantitative responses; then subjected to thematic analysis.

Results
ORTO-15 identified 64% of the participants for orthorexic tendencies. In most cases (76%), participants reported no issues completing the ORTO-15. However, in some cases, qualitative responses differed from quantitative ones. When people encountered problems, it was because of poor psychometric construction: lack of clarity, ambiguous wording and multiple statements in a single item. Elaborations around the ORTO-15 items formed four major themes: “preoccupation with physical appearance”, “control”, “food is fuel” and “alone, not isolated”.

Conclusion
Even though in the majority of cases there were no issues with completing ORTO-15, thematic analysis revealed several discrepancies between our participants’ perceptions of the ORTO-15 items and the previously proposed diagnostic criteria for ON. The results suggest that ORTO-15 is, at best, a mediocre screening tool for ON, which is sensitive to diet but fails to have sufficient level of specificity to detect the pathological stage. More accurate instruments are needed to further research on ON.

Level of evidence
V (cross-sectional descriptive study with qualitative analysis).