bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERUBAHAN STANDAR DESAIN JALAN TAMBANG BOBOKA SITE TANJUNG BULI BERDASARKAN KAJIAN GEOTEKNIK UNTUK MENGURANGI MATERIAL MOVEMENT DAN MEMPERCEPAT DEVELOPMENT JALAN TAMBANG
Authors: Mubarak Zulpryadi , Aditya Eko , MT Dr. Ir. Barlian Dwinagara, 
Published: March 2020

ABSTRAK Pada bulan Januari tahun 2018 PT. Antam Tbk UBP Nikel Maluku Utara, site Tanjung Buli, harus melanjutkan development jalan produksi yang bernama jalan tambang Boboka. Jalan tambang Boboka harus digunakan sebagai jalan produksi pada bulan Juli tahun 2018 agar produksi site Tanjung Buli tetap terjaga. Setelah dilakukan desain berdasarkan standar parameter jalan tambang dan dilakukan estimasi waktu development-nya, jalan tambang Boboka diperkirakan selesai diakhir bulan Agustus 2018. Untuk itu harus dilakukan percepatan pembuatan jalan tambang Boboka. Setelah dilakukan penelitian geoteknik, diketahui bahwa perubahan yang dapat dilakukan untuk standar parameter jalan tambang Boboka adalah dengan menambah tinggi jenjang, lebar berm dan sudut lereng keseluruhan. Perubahannya adalah, tinggi jenjang dari 6 meter menjadi 20 meter, lebar berm dari 3 meter menjadi 5 meter dan sudut lereng keseluruhan dari 45⁰ menjadi 55⁰. Untuk sudut kemiringan lereng tunggal tidak ada perubahan yaitu 60⁰. Dari perubahan tersebut diperoleh kenaikan nilai FK dari 1,30 menjadi 1,65. Perubahan standar parameter tersebut membuat moving material dari development jalan tambang Boboka berkurang secara signifikan sehingga waktu development jalan tambang Boboka dapat dipercepat. Selain itu, dengan berkurangnya moving material development jalan tambang Boboka, PT Antam Tbk UBP Nikel Maluku Utara dapat melakukan efisiensi. Kata kunci: jalan tambang, penelitian geoteknik, moving material. ABSTRACT In January 2018 PT. Antam Tbk UBP Nickel North Maluku, Tanjung Buli site, must continue the development of a production road called the Boboka mining road. The Boboka mine road must be used as a production road in July 2018 so that the production of the Tanjung Buli site is maintained. After the design is based on the standard mining road parameters and estimated development time, the Boboka mine road is estimated to be completed by the end of August 2018. For this reason, acceleration of the construction of the Boboka mine road must be made. After conducting geotechnical research, it is known that changes that can be made to the standard parameters of the Boboka mine road are adding height, berm width and overall slope angle. The changes are, the height of the level from 6 meters to 20 meters, berm width from 3 meters to 5 meters and the overall slope angle from 45⁰ to 55⁰. For a single slope angle there is no change that is 60⁰. From these changes an increase in FK values was obtained from 1,30 to 1,65. The change in standard parameters made the moving material from the development of the Boboka mine road significantly reduced so that the development time of the Boboka mine road could be accelerated. In addition, with the reduction in moving material development of the Boboka mine road, PT Antam Tbk UBP Nickel North Maluku can improve efficiency. Keywords: mining road, geotechnical research, moving material.
ANALISIS STABILITAS TEROWONGAN DANGKAL PADA TANAH LUNAK
Authors: Dhanti Putri Nova Haryu , Saptono Singgih 
Published: March 2020

ABSTRAK Pada lima tahun terakhir ini banyak pembangunan yang dilakukan di Indonesia khususnya pembangunan infrastruktur, seperti pembangunan sarana Mass Rapid Transportation (MRT) berupa terowongan di Jakarta, dan berapa terowongan jalan raya dan terowongan jalur kereta api. Hal ini menjadi tantangan bagi para pembuatan terowongan di Indonesia. Tantangan tesebut adalah membuat terowongan jalan raya dan kereta api pada tanah lunak khususnya lempung dan pada kedalaman yang dangkal. Hal ini perlu perhatian khusus, disebabkan oleh sifat lempung yang memiliki sifat swelling dan serta penggalian terowongan tersebut pada kedalamanan kurang dari 100 m. Pendekatan kekuatan batuan sudah tidak dapat digolongan sebagai batuan karena pada umumnya menurut meterial lempung digolongkan sebagai tanah, sehingga teori elastistas sudah tidak berlaku lagi. Pendekatan yang diusulkan untuk analisis stabilitas pada terowongan di batuan lempung adalah berperilaku swelling sesuai dengan kandungan mineral penyusunnya yaitu montmorilonit. Untuk itu analisis stabiltas diperlukan parameter swelling. Pada Analisis dengan perilaku sewlling ini menggunakan metode elemen hingga (Phase2, Rocscience). Dengan pendekatan perilaku Swelling dalam analisis stabilitas terwongan akan lebih mendekati dengan sifat material yang ada di terowongan. Kata kunci: swelling, metode elemen hingga, stabilitas, terowongan ABSTRACT In the last five years a lot of development has been carried out in Indonesia, especially infrastructure development, such as the construction of Mass Rapid Transportation (MRT) facilities in the form of tunnels in Jakarta, and how many road tunnels and railroad tunnels. This is a challenge for tunnels in Indonesia. The challenge is to build road and rail tunnels on soft soil, especially clays and at shallow depths. This needs special attention, due to the nature of the clay which has swelling properties and the excavation of the tunnel in the depth of less than 100 m. Rock strength approach can no longer be classified as rock because in general according to clay meterial classified as soil, so the theory of electricity is no longer valid. The proposed approach for the stability analysis of tunnels in clay rock is to behave swelling according to its constituent mineral content, montmorillonite. For this reason, stability analysis requires swelling parameters. In this analysis with sewlling behavior using the finite element method (Phase2, Rocscience). With the Swelling behavior approach in the tunnel stability analysis it will be closer to the material properties in the tunnel. Key words : Swelling, Finite Element Method, Stability, Tunnel
<b>Digital Games about the Materiality of Digital Games</b> // Juegos digitales sobre la materialidad de los juegos digitales
Authors: Nguyen Josef 
Published: April 2020

This article investigates the potential for digital games to advance environmentally responsible attitudes by attending to their own material conditions, since the production, consumption, and disposal of games and the platforms on which they run enact ecological harm. I examine how Tomorrow Corporation’s puzzle game Little Inferno (2012) and Molleindustria’s political mobile game Phone Story (2011) address their own participation in ecological harm through rendering visible the very games themselves being played as material commodities. In doing so, they acknowledge their own complicity as well as that of their players in existing processes of environmental degradation. Moreover, both games challenge conventional expectations of fun as harmless or inconsequential, since this environmental destruction results from digital entertainment. I argue that digital games advancing environmentally responsible attitudes must address the ecological devastation tied to their materiality as well as support players in accepting responsibility for and remedying the harm players enact. Consequently, digital games of environmental responsibility must also question the dominant mode of fun that drives ecological devastation by reminding us that we dwell in a world where we need to be responsible for the fun we choose to have. Resumen Este artículo investiga el potencial de los juegos digitales para fomentar actitudes responsables hacia el medioambiente atendiendo a sus propias condiciones materiales, ya que la producción, el consumo, y el desecho de los juegos y de las plataformas en las que funcionan representan daño ecológico. Examino cómo el puzle Little Inferno (2012) de Tomorrow Corporation y el juego político para móvil Phone Story (2011) de Molleindustria abordan su propia participación en el daño ecológico haciendo visible el que los juegos en sí mismos sean productos materiales. Al hacerlo, reconocen su propia complicidad, así como la de los jugadores en los procesos de degradación medioambiental. Además, ambos juegos desafían las expectativas convencionales de la diversión como algo inofensivo e intrascendente, ya que esta destrucción medioambiental resulta del entretenimiento digital. Argumento que los juegos digitales que promueven actitudes responsables hacia el medioambiente deben abordar la devastación ecológica vinculada a su materialidad, así como animar a los jugadores a que acepten su responsabilidad y corrijan el daño que hacen. En consecuencia, los juegos digitales con responsabilidad medioambiental deben también cuestionar la forma dominante de diversión que conlleva devastación ecológica recordándonos que vivimos en un mundo en el que necesitamos ser responsables de la diversión que elegimos tener.
Effect of Disease Activity on Organ Damage Progression in Systemic Lupus Erythematosus: University of Toronto Lupus Clinic Cohort
Authors: Urowitz Murray B. , Gladman Dafna D. , Ibañez Dominique , Su Jiandong , Mursleen Sara , Sayani Amyn , Ross Terres Jorge Alfonso , Iczkovitz Sandra 
Published: April 2020

Objective.To examine the role of disease activity on organ damage over 5 years in patients with active systemic lupus erythematosus (SLE) despite standard of care.Methods.This analysis of the University of Toronto Lupus Clinic cohort assessed organ damage [measured by Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI)] in patients with active SLE [SLE Disease Activity Index 2000 (SLEDAI-2K) ≥ 6], using Cox proportional time-independent hazard models. Subgroup analyses were conducted in patients with SLEDAI-2K 6 or 7, 8 or 9, and ≥ 10 at baseline, and in the overall study population by steroid dose at study entry (< 7.5 vs ≥ 7.5 mg/day).Results.Among the overall study population (n = 649), SDI progression was observed in 209 (32.2%) patients over the 5-year follow-up period. Mean SDI change in patients with a score > 0 was generally consistent across all SLEDAI-2K subgroups. Multivariable analyses identified age at study start (HR 1.03, P < 0.0001), steroid dose (HR 2.03, P < 0.0001), immunosuppressants (HR 1.44, P = 0.021), and SLEDAI-2K (subgroup analyses HR 1.64–2.03, P = 0.0017 to < 0.0001) as the greatest risk factors for SDI progression, while a study start date after the year 2000 had a protective effect on SDI progression compared with a start date prior to the year 2000 (HR 0.65, P = 0.0004).Conclusion.Patients within the higher SLEDAI-2K subgroups at study entry or receiving high doses of steroids were more likely to have organ damage progression.
Innate-like CD27+CD45RBhigh γδ T Cells Require TCR Signaling for Homeostasis in Peripheral Lymphoid Organs
Authors: Tani-ichi Shizue , Wagatsuma Keisuke , Hara Takahiro , Cui Guangwei , Abe Shinya , Miyachi Hitoshi , Kitano Satsuki , Ikuta Koichi 
Published: April 2020

Abstract
TCR signaling is required for homeostasis of naive αβ T cells. However, whether such a signal is necessary for γδ T cell homeostasis in the periphery remains unknown. In this study, we present evidence that a portion of Vγ2+ γδ T cells, one of the major γδ T cell subsets in the secondary lymphoid organs, requires TCR signaling for homeostasis. To attenuate γδTCR signals, we generated mice lacking Eγ4 (Eγ4−/−), an enhancer located at the 3′-most end of the TCRγ locus. Overall, we found that in thymus, Eγ4 loss altered V-J rearrangement, chromatin accessibility, and transcription of the TCRγ locus in a distance-dependent manner. Vγ2+ γδ T cells in Eγ4−/− mice developed normally both fetal and adult mouse thymi but were relatively reduced in number in spleen and lymph nodes. Although Vγ2 TCR transcription decreased in all subpopulations of Eγ4−/− mice, the number of Vγ2+ γδ T cells decreased and TCR signaling was attenuated only in the innate-like CD27+CD45RBhigh subpopulation in peripheral lymphoid organs. Consistently, CD27+CD45RBhigh Vγ2+ γδ T cells from Eγ4−/− mice transferred into Rag2-deficient mice were not efficiently recovered, suggesting that continuous TCR signaling is required for their homeostasis. Finally, CD27+CD45RBhigh Vγ2+ γδ T cells from Eγ4−/− mice showed impaired TCR-induced activation and antitumor responses. These results suggest that normal homeostasis of innate-like CD27+CD45RBhigh Vγ2+ γδ T cells in peripheral lymphoid organs requires TCR signaling.
IRAK1 Is a Critical Mediator of Inflammation-Induced Preterm Birth
Authors: Jain Viral G. , Kong Fansheng , Kallapur Suhas G. , Presicce Pietro , Senthamaraikannnan Paranthaman , Cappelletti Monica , Chougnet Claire A. , Bhattacharyya Sandip , Pasare Chandrashekhar , Muglia Louis J. 
Published: April 2020

Abstract
Preterm birth (PTB) is a major cause of neonatal mortality and morbidity, often triggered by chorioamnionitis or intrauterine inflammation (IUI) with or without infection. Recently, there has been a strong association of IL-1 with PTB. We hypothesized that IL-1R–associated kinase 1 (IRAK1), a key signaling mediator in the TLR/IL-1 pathway, plays a critical role in PTB. In human fetal membranes (FM) collected immediately after birth from women delivering preterm, p-IRAK1 was significantly increased in all the layers of FM with chorioamnionitis, compared with no-chorioamnionitis subjects. In a preterm rhesus macaque model of IUI given intra-amniotic LPS, induction of p-IRAK1 and downstream proinflammatory signaling mediators were seen in the FM. In a C57BL/6J wild-type PTB mouse model of IUI given intrauterine LPS, an IRAK1 inhibitor significantly decreased PTB and increased live birth in a dose-dependent manner. Furthermore, IRAK1 knockout mice were protected from LPS-induced PTB, which was seen in wild-type controls. Activation of IRAK1 was maintained by K63-mediated ubiquitination in preterm FM of humans with chorioamnionitis and rhesus and mouse IUI models. Mechanistically, IRAK1 induced PTB in the mouse model of IUI by upregulating expression of COX-2. Thus, our data from human, rhesus, and mouse demonstrates a critical role IRAK1 in IUI and inflammation-associated PTB and suggest it as potential therapeutic target in IUI-induced PTB.
Chemotherapy-induced pulmonary complications in cancer: Significance of clinicoradiological correlation
Authors: Dhamija Ekta , Meena Pankaj , Ramalingam Vidyasagar , Sahoo Ranjeet , Rastogi Sameer , Thulkar Sanjay 
Published: March 2020

AbstractChemotherapy while revolutionizing cancer management by improving survival and quality of life; is also associated with several adverse effects. Lung is the most common organ affected in chemotherapy-related complications, due to either drug toxicity or more commonly due to infections caused by immunosuppression and less commonly due to immune-mediated injury. Radiology, when used in combination with clinical and lab data, can help reach the specific diagnosis or narrow down the differentials. The common radiological patterns of drug toxicity include pulmonary interstitial and airway infiltrates, diffuse alveolar damage, nonspecific interstitial pneumonia, eosinophilic pneumonia, cryptogenic organizing pneumonia, pulmonary hemorrhage, edema and hypertension. Cancer patients are immunosuppressed due to the underlying malignancy itself or due to therapy and are prone to a gamut of opportunistic infections including viral, bacterial, fungal and mycobacterial pathogens. Immune reconstitution inflammatory syndrome (IRIS), a well-known complication in HIV, is now being increasingly recognized in non-HIV patients with immunosuppression. Engraftment syndrome is specifically seen following hematopoietic stem cell transplant during neutrophil recovery phase. Pulmonary involvement is frequent, causing a radiological picture of noncardiogenic pulmonary edema. Thus, radiology in combination with clinical background and lab parameters helps in detecting and differentiating various causes of pulmonary complications. This approach can help alter potentially toxic treatment and initiate early treatment depending on the diagnosis.
SAPHO syndrome: A radiological case report
Authors: Singh Anil Kumar , Ranjan Rahul S 
Published: March 2020

AbstractThe SAPHO syndrome (synovitis–acne–pustulosis–hyperostosis–osteitis syndrome) is a rare chronic inflammatory disease of unknown etiology. Herein, we present a case of incidentally detected SAPHO syndrome in a middle-aged male patient who visited the hospital for pulmonary complaints.
Utility of Doppler ultrasound in early-onset neonatal sepsis
Authors: Ratnaparkhi Chetana R , Bayaskar Madhura V , Dhok Avinash P , Bhende Vikrant 
Published: March 2020

AbstractBackground: Neonatal sepsis is an important cause of morbidity and mortality among newborns. As there is paucity of literature regarding early alteration of the cerebral blood flow (CBF) in neonatal sepsis our study aims to evaluate the changes in the CBF velocities and Doppler indices in neonates with early-onset neonatal sepsis (EONS) and to evaluate the predictive accuracy of cerebral blood flow velocities (CBFV) by using ultrasound Doppler as a diagnostic marker of EONS. Methods: This cross-sectional analytical study was conducted over a period of 2 years with 123 neonates enrolled in the study. The neonates were divided into two groups: Group I (with 54 neonates) - neonates with EONS and group II (with 69 neonates) - age-matched neonates without any signs of sepsis. Ultrasound Doppler examination was performed and the cerebral hemodynamics assessed in neonates during the first seventy two hours of life. Doppler indices and CBFV were measured in the internal carotid artery (ICA), middle cerebral artery (MCA), and vertebral artery (VA) of either side. Data were analyzed using the statistical program SPSS version 23.0 (SPSS Inc., Chicago, IL, USA). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy were calculated at different selected cutoff values for CBFV parameters. Results: Lower resistance and higher peak systolic velocity and end diastolic velocity have been documented in neonates with EONS. Conclusion: Our study shows that the cerebral hemodynamics in neonates with EONS is altered which can be assessed bedside by noninvasive ultrasound Doppler examination.
Interrupted aortic arch: A case report
Authors: Franconeri Andrea , Ballati Francesco , Pin Maurizio , Carone Luisa , Danesino Gian M , Valentini Adele 
Published: March 2020

AbstractInterrupted aortic arch diagnosed in adult age is a rare entity, with only a few cases published in the literature. Most of them are classified as type A interrupted aortic arch and differential diagnosis is associated with severe chronic coarctation. We present a case of a 52-year-old woman accessed to the emergency department for chest and right upper limb pain that increased in the last days. She underwent a computed tomography angiogram showing interruption of the aortic arch, distal to left subclavian artery origin, large bilateral collateral vessels connecting subclavian arteries to descending aorta with multiple voluminous aneurysms, a bicuspid aortic valve, dilatated tubular segment of ascending thoracic aorta, and a suspected atrial septal defect. A nonsystematic literature review regarding these conditions has been performed.
MDCT evaluation of intramyocardialsinusoids-coronary artery communications in a neonate with pulmonary atresia and intact ventricular septum
Authors: Das Karuna M , Almansoori Taleb M , Momenah Tarek Suliman , Gorkom Klaus Neidl-Van 
Published: March 2020

AbstractA patient of tetrology of Fallot with complete atresia of the pulmonary outflow tract with ventriculocoronary connections is presented.MDCT imaging revealed left coronary sinus, with a large fistula draining into the free wall of hypoplastic right ventricular cavity with tortuous channel arising from right ventricular outflow, and communicating with proximal limb of the fistula forming a complete loop suggesting a right ventricle–to – left coronary sinus sinusoid.
A study to assess the knowledge and practice of medical professionals on radiation protection in interventional radiology
Authors: Shafiee Mohsen , Rashidfar Razieh , Abdolmohammadi Jamil , Borzoueisileh Sajad , Salehi Zaker , Dashtian Kheibar 
Published: March 2020

Abstract
Objective: Ionizing radiation has been extensively used in medical procedures throughout the world. Such interventional radiological procedures could result in occupational exposure that needs urgent control. Therefore, MPs (medical professionals) should receive education and appropriate training on occupational radiation protection. In this context, the present study is aimed to investigate the MPs’ knowledge and practice regarding radiation protection principles during interventional radiological procedures. Material and Methods: A descriptive questionnaire-based study was carried out among 215 MPs involved in interventional fluoroscopy procedures. The practice of 31 MPs was studied using a checklist based on ALARA principles and ICRP guidelines. Results: A total of 43.3% and 45.1% answered correctly for knowledge and practice. However, the difference between radiation protection knowledge and practice between the physicians and nurses was statistically significant. The knowledge and practice survey of MPs demonstrated that nurses rarely adhered to radiation-protection measures. Conclusion: The present study reflects the lack of knowledge and practice concerning radiation protection concepts among the nurses. This deficiency needs to be resolved by periodic practical radiation protection courses in the curriculum of medicine.
Hereditary hemorrhagic telangiectasia of liver: Pathophysiology with role of radiology in diagnosis and treatment
Authors: Viyannan Maheswaran , Balalakshmoji Devanand , Leelakrishnan Venkatakrishnan 
Published: March 2020

AbstractHereditary hemorrhagic telangiectasia (HHT) or Osler–Weber–Rendu syndrome is a rare condition which can result in significant systemic and hepatobiliary abnormalities. Liver involvement in HHT consists primarily of the consequence of various intrahepatic shunts. Even though these vascular shunts are present in the majority of patients with HHT, symptoms occur only in minority with clear predilection to female gender. The symptoms and imaging findings of liver vascular malformations can be easily overlooked or misdiagnosed which can result in delay in treatment or potentially harmful vascular interventions. In this case report, we discuss the pathophysiology of HHT in liver involvement, role of imaging in diagnosis, and the possible role of interventional radiologist in the treatment.
Myositis ossificans of mobile wad of Henry-Tennis elbow mimic
Authors: Almeer Ghassan , Azzopardi Christine , Kho James , Botchu Rajesh 
Published: March 2020

AbstractLateral epicondylitis also known as “tennis elbow” is the most common cause of lateral elbow pain. Several pathologies can mimic symptoms of tennis elbow. We present a case of myositis ossificans within the mobile wad of Henry (MWH), which presented with symptoms of tennis elbow and believe this to be the first reported case in literature.
18F-FDG PET/CT in cyst infection in autosomal dominant polycystic kidney disease
Authors: Prabhu Meghana , Damle Nishikant A , Ray Animesh , Kandasamy Devasenathipathi 
Published: March 2020

AbstractInfection of a cyst within an autosomal dominant polycystic kidney disease (ADPKD) is a serious complication. Diagnosis with conventional imaging techniques such as ultrasonography, computed tomography (CT), and magnetic resonance imaging can be sometimes challenging. The definite diagnosis is analysis of the cyst fluid, but cyst punctures can cause bleeding, rupture, and contamination of adjacent cysts. Recently, FDG PET/CT has been reported as a sensitive tool for detection of cyst infection. We describe a case of 63-year-old woman with infected cysts in the left kidney, in whom accurate diagnosis was made on FDG PET/CT. FDG PET/CT is an important investigation in patients with fever of uncertain etiology, where renal cyst infection is a possible cause, but other etiologies also need to be ruled out.