bluuebunny/crossref_metadata_2025_split huggingface dataset:
CIVIL WAR IN RUSSIA (ON THE EXAMPLE OF KALUGA PROVINCE)
Authors: Белова Ирина Борисовна 
Published: December 2020

Статья посвящена общественно-политической и социально-экономической ситуации в период Гражданской войны (1917-1922 гг.) в Калужской губернии, одной из центральных губерний Европейской России, находившейся вне театра военных действий. Автором освещён сложный процесс прихода к власти большевиков, который завершился только под угрозой применения ими вооруженной силы против защитников прежней власти. В статье показаны формы сопротивления населения большевистской политике «военного коммунизма», способы реагирования власти на сопротивление, конец и итоги этой политики. Автор отмечает, что катастрофическая ситуация с продовольственным снабжением в губернии способствовала стихийному бегству коренного и беженского населения в производящие юго-восточные регионы и за Урал.
The article deals with the sociopolitical and socioeconomic situation in Kaluga province which was one of the central provinces in European part of Russia outside the theatre of operations during the Civil war (1917-1922).The author highlights the complex process of Bolsheviks installation which was completed only after they threatened to use military force against the defenders of the former regime. The article covers the forms in which the population of the province resisted the Bolshevik policy of «military communism», the ways the authorities reacted to the resistance and the outcome of this policy. The author points out that the catastrophic situation with food supply contributed to chaotic exodus of the natives and the refugees to the producing south-east regions and behind the Urals.
FOR THE 200-TH ANNIVERSARY OF IVAN EGOROVICH ZABELIN
Authors: Воробьева Ирина Геннадиевна 
Published: December 2020

Сообщение посвящено 200-летию со дня рождения Ивана Егоровича Забелина (1820-1909), историка, археолога, создателя Императорского российского исторического музея (ГИМ), автора книг по истории Москвы и бытописанию жизни русских царей и цариц. И.Е. Забелин родился в Твери, о чём есть запись в метрической книге церкви святителя Николая на Зверинце, хранящейся в фонде Тверской духовной консистории. На основе переписки историка с членами Тверской учеёной архивной комиссии рассмотрены его отношения с земляками, сотрудничество Тверского музея с Историческим музеем в Москве, сохранение памяти И.Е. Забелина в Научной библиотеке Тверского государственного университета.
This message is devoted to the 200-th anniversary of the birth of I.E. Zabelin (1820-1909), the historian, archaeologist, founder of the Empire Russian Historical Museum (GIM), the author of the books about the history of Moscow and the everyday life of Russian tsars and tsarinas. I.E. Zabelin was born in Tver, and there is a record about it in the register of births of the church of St. Nicolas «on the Menagerie», that is being kept in the fund of Tver Spiritual Consistory. The relations of this historian with his natives, the collaboration of the Tver Museum and the Moscow Historical Museum and the theme of the preservation of memory of I.E. Zabelin in the Scientific Library of the Tver State University are considered upon the data of his correspondence with the members of the Tver Scientific Archive Commission.
SETS OF CLOTHES AND DECORATIONS IN THE LISTS OF THE DOWRY OF THE XVII CENTURY FROM THE COLLECTION OF THE TVERSKY STATE JOINT MUSEUM
Authors: Степанова Юлия Владимировна 
Published: December 2020

В статье рассматриваются описи приданого второй половины XVII в., выявленные в коллекции документов столбцового делопроизводства Тверского государственного объединенного музея. Документы относятся к частным архивам семейств служилых людей, территориально связанных в Верхневолжьем и Подмосковьем: Теприцких, Скорятиных, Киреевских, Суворовых. Описи выявлены в составе сговорных и рядных грамот, и как самостоятельные документы. Перечни движимого имущества включают украшения и предметы одежды, характеризующие владельцев как сравнительно обеспеченных людей. Это обязательные элементы гардероба: меховые шубы и шапки. Более вариативным является набор остальных вещей: охабней, ферязей, кафтанов, однорядок, телогрей. В обязательный набор ювелирных изделий входили предметы личного благочестия: кресты с цепочками, а также серьги и перстни. Описи приданого отражают характерные явления моды последней четверти XVII в. Источники демонстрируют высокую ценность предметов одежды и украшений в материальном обиходе провинциального дворянства конца XVII в., вне зависимости от материальной стоимости изделий, так как в них наряду с престижными дорогими вещами включались и детально описывались и предметы менее ценные, изготовленные из недорогих материалов.
The article is devoted to the records of the dowry of the second half of the 17th century, revealed in the collection of documents of the column office work ( stolbtsy ) of the Tver State Joint Museum (TSJM), No. 1431. The documents relate to private archives of families of service class, geographically connected with Upper Volga region (Tverskoi, Jarovskii, Uglichskii, Bezhetskii, Kashinskii uezds, etc.) and Moscow region (Dmitrovskii uezd): Tepritskiуe, Skoryatny, Kireevsky, Suvorov. The lists are revealed both as part of collusion and contract records, and as independent documents. Lists of movable property include decorations and garments characterizing owners as comparatively well-off people. These are the mandatory elements of the wardrobe: fur coats and caps. More variable is the set of other things: okhaben’, feras, kaftan, odnoryadka, telogreia . The mandatory set of jewelry included items of personal piety: crosses with chains, as well as earrings and finger rings. The descriptions of the dowry reflect the characteristics of fashion of the last quarter of the 17th century. The sources demonstrate the high value of clothing and jewelry in the material environment of the provincial nobility of the late 17th century, regardless of the cost of the things. Along with prestigious expensive things, items of less valuable, made from inexpensive materials were included and described in detail.
WOMEN'S EDUCATION IN TVER IN THE SECOND HALF OF THE XIX - EARLY XX CENTURIES
Authors: Цыганова Ангелина Валерьевна 
Published: December 2020

В статье рассматривается история становления различных типов женских учебных заведений в Твери во второй половине XIX - начале XX вв. Архивные материалы, привлеченные к исследованию, раскрывают организацию учебного и воспитательного процесса, содержание учебных планов, недельное распределение уроков, численный и сословный состав обучающихся, административный и педагогический состав, правила проведения вступительных и экзаменационных испытаний и т.д. в женских учебных заведениях. Приводятся данные по распределению численности средних женских учебных заведений в Тверской губернии, количественному составу учениц, учебным предметам, срокам обучения в школе П.П. Максимовича, Постоянных педагогических курсах, Тверской Мариинской женской гимназии. Подчеркивается роль женских средних школ для подготовки учительских кадров в Тверской губернии. Автор делает вывод о значительном потенциале развития всесословной женской средней школы в российской провинции.
The article examines the history of the formation of various types of women's educational institutions in Tver in the second half of the XIX - early XX centuries. The archival materials involved in the study reveal the organization of the educational process, the content of the curriculum, the weekly distribution of lessons, the number and class composition of students, administrative and pedagogical staff, the rules for conducting entrance and examination tests, etc.in women's educational institutions. Data on the distribution of the number of secondary female educational institutions in the Tver province, the number of female students, academic subjects, terms of study at the P.P. Maksimovich school, Permanent pedagogical courses in Tver and Tver Mariinsky girls ' gymnasium are presented. The role of women's secondary schools for training teachers in the Tver province is emphasized. The author concludes that there is a significant potential for the development of an all-female secondary school in the Russian province.
Pre and Post Covid-19 Lockdown: How the AQI of Three Major Cities of Pakistan will Change?
Authors: Ume Laila  , Najma Sadiq  , Tahir Mehmood  , Tooba Rehan Haqqi  
Published: December 2020

Pakistan being in the list of developing countries has shown tremendous response towards the control of pandemic COVID-19. This paper evaluates the pre and post COVID 19 lockdown situation of air quality and provides an evidence of the air quality amid the lockdown and how it started to improve. The air quality indexes of three major cities of Pakistan i.e. Karachi, Islamabad and Lahore are compared, taking into account the indexes before and after the imposition of lockdown. The city wide presence of major pollutants like Sulphur Dioxide and Nitrogen Dioxide also reduced. The results show how taking serious measures can help in reducing the air pollution and help the environment to restore. Following analytical approach and situational analysis certain inferences have been drawn that the air quality index has worsen, and the atmospheric condition have turn out to be shoddier than the pre-pandemic situation. In the last section certain policy recommendations have been provided in order to maintain a healthy air quality.
Medical information system for the rapid screening of cardiovascular risk in patients after coronary stenting
Authors: Pushkarev G. S. , Kuznetsov V. A. , Guskova O. A. , Malishevsky L. M. 
Published: December 2020

Aim. To develop and implement a decision support system for a software product – medical information system “1C: Medicine” in the form of calculator for assessment of the absolute risk of death from cardiovascular diseases (CVD) and to show the prospects of using this system for patients with coronary artery disease (CAD) after coronary stenting.Material and Methods. The medical information system “1C: Medicine” software interface was developed in Tyumen Cardiology Research Center. It was designed to assess 10-year absolute total mortality risk from CVD in males of working age (Tyumen Risk Scale (TRS)) to provide medical decision support. The program was tested in 764 male patients from the Prospective Registry of Percutaneous Coronary Interventions (PCI). The mean age of patients was 56.9 ± 8.8 years. All death cases, recorded within a year after PCI (n = 23), were used as the status check variable. The following algorithms were chosen to compare the predictive accuracy of the integrated model: PROCAM and FRAMINGHAM. The Schwarz information test and ROC analysis data were used to assess the predictive accuracy of the models.Results. The values of Schwarz’s criterion in males were 283 for TRS, 235 for PROCAM, and 490 for FRAMINGHAM model. AUC indicator for TRS was 0.655 (95% CI 0.510–0.800), suggesting the satisfactory quality of resulting model. AUC indicators for FRAMINGHAM and PROCAM algorithms were 0.599 (95% CI 0.442–0.757) and 0.653 (95% CI 0.509–0.796), respectively.Conclusion. The created TRS, integrated into the medical information system with psychosocial factors, may be quickly and successfully implemented to determine mortality risk in CAD patients within one year after coronary stenting. The TRS has an advantage over the traditional FRAMINGHAM risk scale and non-inferior to the PROCAM scale. Therefore, TRS may be used as a medical decision support program.
Predictive potential assessment of preoperative risk factors for atrial fibrillation in patients with coronary artery disease after coronary artery bypass grafting
Authors: Shakhgeldyan K. I. , Rublev V. Y. , Geltser B. I. , Shcheglov B. O. , Shirobokov V. G. , Dukhtaeva M. K. , Chernysheva K. V. 
Published: December 2020

Introduction. Postoperative atrial fibrillation (POAF) is one of the most common complications of coronary artery bypass grafting (CABG) and occurs in 25–65% of patients.Aim. The study aimed to assess the predictive potential of preoperative risk factors for POAF in patients with coronary artery disease (CAD) after CABG based on machine learning (ML) methods.Material and Methods. An observational retrospective study was carried out based on data from 866 electronic case histories of CAD patients with a median age of 63 years and a 95% confidence interval [63; 64], who underwent isolated CABG on cardiopulmonary bypass. Patients were assigned to two groups: group 1 comprised 147 (18%) patients with newly registered atrial fibrillation (AF) paroxysms; group 2 included 648 (81.3%) patients without cardiac arrhythmia. The preoperative clinical and functional status was assessed using 100 factors. We used statistical analysis methods (Chi-square, Fisher, Mann – Whitney, and univariate logistic regression (LR) tests) and ML tests (multivariate LR and stochastic gradient boosting (SGB)) for data processing and analysis. The models’ accuracy was assessed by three quality metrics: area under the ROC-curve (AUC), sensitivity, and specificity. The cross-validation procedure was performed at least 1000 times on randomly selected data.Results. The processing and analysis of preoperative patient status indicators using ML methods allowed to identify 10 predictors that were linearly and nonlinearly related to the development of POAF. The most significant predictors were the anteroposterior dimension of the left atrium, tricuspid valve insufficiency, ejection fraction <40%, duration of the P–R interval, and chronic heart failure of functional class III–IV. The accuracy of the best predictive multifactorial model of LR was 0.61 in AUC, 0.49 in specificity, and 0.72 in sensitivity. The values of similar quality metrics for the best model based on SGB were 0.64, 0.6, and 0.68, respectively.Conclusion. The use of SGB made it possible to verify the nonlinearly related predictors of POAF. The prospects for further research on this problem require the use of modern medical care methods that allow taking into account the individual characteristics of patients when developing predictive models.
Predicting various forms of endometriosis using artificial neural networks
Authors: Sazonova N. G. , Makarenko T. A. , Narkevich A. N. 
Published: December 2020

Introduction. Endometriosis is a difficult-to-diagnose pathology due to the diversity of clinical manifestations and the lack of high-precision markers necessary for rapid noninvasive diagnosis and timely administration of pathogenetically justified treatment.The aim of this work was to develop a computer system that allows us to assess the probability of endometriosis with various localizations in women, based on artificial neural networks.Material and Methods. The neural network mathematical models were constructed and tested based on data from 110 patients with morphologically pre-confirmed endometriosis. Patients were divided into training and test samples. The models were built based on anamnestic data and results of proteomic and enzyme immunoassays in blood plasma samples.Results and Discussion. In the course of the study, four mathematical models of neural networks were constructed to predict the presence or absence of endometriosis in a woman and its localization if present. Based on these mathematical models, a computer system “Differential diagnosis of endometriosis” was developed. This system allowed to assess the probability and localization of endometriosis in a patient based on parameters obtained as a result of neural network training.Conclusion. The developed computer diagnostic system allowed predicting the presence of endometriosis and its localization with a probability over 80%, depending on the predicted localization, based on data about the patient and the results of her examination. This system may be used for differential diagnosis of endometriosis from other diseases of the female reproductive system, as well as for differential diagnosis of various endometriosis localizations.
Mathematical models in cardiology: From formulas to real clinical practice
Authors: Kuznetsov V. A. , Gapon L. I. , Malishevskii L. M. , Lobuntsov D. S. , Dziabenko E. A. , Soldatova A. M. , Pushkarev G. S. , Todosiychuk V. V. , Yaroslavskaya E. I. 
Published: December 2020

Aim. To develop and implement into clinical practice six calculators of risk for various cardiovascular diseases in the form of mobile application for iOS/Android and module for the 1C: Medicine software.Material and Methods. At the premises of Tyumen Cardiology Research Center (TCRC) of Tomsk NRMC, we developed the mobile application for iOS/Android and module for the 1C: Medicine software based on six mathematical models that were invented and patented in our center earlier.Results and Discussion. The use of mobile application improved the convenience of working with the mathematical formulas and reduces the time for obtaining results of calculations. Implementation of 1C as a programming environment allowed to perform automatic filling out the calculator fields with medical data from individual patients, which significantly simplified and accelerated the rate of work with mathematical models.Conclusion. The developed mobile application and external processing for 1C allowed to implement research products of TCRC in the form of mathematical formulas into real-life clinical practice. These developments contributed to speeding up the process for acquisition of results and partial automatization of filling out the form fields.
Predicting the birth of a large fetus in obese women
Authors: Savelyeva I. V. , Bukharova E. A. , Shirokova O. V. , Nosova N. V. 
Published: December 2020

Purpose. To determine the risk of macrosomia in pregnant women as a function of body weight.Material and Methods. The study included 754 patients. All patients were divided into three groups. Group 1 included 262 obese patients with an average body mass index (BMI) of 33.1 (31.4; 35.9) kg/m2, aged 30 (27; 34) years. Group 2 comprised 260 overweight patients with an average body mass index of 27.5 (26.4; 28.7) kg/m2, aged 29 (25; 33) years. Group 3 (control) included 232 patients with normal body weight, BMI of 22.6 (21.0; 23.8) kg/m2, aged 28 (25; 31.5) years. Anthropometric data were assessed in all patients with the performance of general clinical and laboratory examinations.Results. Based on the results of logistic regression analysis for continuous variables, a prognostic model for the birth of a large fetus with a probability of up to 70.3% was constructed.
Evaluation of pharmacokinetic properties of isobornylphenols <em>in silico</em>
Authors: Ostrikova O. I. , Vaizova O. E. , Aliev O. I. , Buravlev E. V. , Chukicheva I. Yu. , Kutchin A. V. 
Published: December 2020

Introduction. The potential of a new compound in the ongoing drugs discovery process is initially explored using virtual instruments, where its activity is predicted based on its molecular structure.Aim. This study aimed to evaluate the pharmacokinetic parameters and possible toxicity of isobornyl compounds based on virtual tools.Material and Methods. Several free Internet resources were used to assess the absorption, distribution, metabolism, excretion (ADME), and toxicity (T) of 2,6-diisobornyl-4-methylphenol (1, Dibornol), 2-hydroxy-3-isobornyl-5-methylbenzaldehyde (2), and 2-((di-n-butylamino) methyl)-6-isobornyl-4-methylphenol (3). Pharmacokinetic properties were calculated on ADMETlab platform. Toxicity and physical properties were evaluated using TEST software based on the structure-property quantification models of organic substances according to structure–property principle. Web server ProTox_II was used for acute toxicity assessment.Results. Plasma protein binding degrees were 76,9% for (1), 85,9% for (2), and 91,8% for (3). All three compounds were capable of penetrating the blood-brain barrier. Dibornol was identified neither as a substrate nor as an inhibitor of P-glycoprotein unlike (2) and (3). The half-life of all compounds was short (about 2 hours); the clearance was slow (about 2 mL/min*kg). The study showed that (2) and (3) potentially exert the toxic effects during the developmental stage of the organism, while ADMETlab showed potential cardio- and hepatotoxicity for (2) and (3), respectively. All compounds had extremely low solubility in water, which affected the assessments of other indicators by TEST software. The ProTox_II server showed the extremely low toxicity LD50 for all compounds (toxicity class 5).
On the capability of measuring the dielectric constant of human organs and tissues by radar sensing and mathematical modeling
Authors: Avdochenko B. I. , Repenko V. D. , Ubaychin A. V. , Fateev A. V. , Khatkov N. D. , Issakov V. 
Published: December 2020

Purpose of work. An implementation of small-sized high-resolution radar systems is proposed to solve both the problem of access to digital technologies and the development of preventive medicine and telemedicine.Method of research. The use of ultra-wideband video pulses, stroboscopic receivers, and laptops with specialized software allows to create an inexpensive diagnostic medical device. Working with such a diagnostic medical device does not require participation of highly qualified medical and radio engineering specialists.Research materials. The block diagram of the diagnostic device and experimental methodology are described. Preliminary tests of the diagnostic device are carried out. A capability to provide a millimeter-accuracy spatial resolution of a human body internal structure is presented. The mathematical model of interaction between the radio pulse and internal in homogeneities in the human body and the principle of processing the reflected signal are described.Results. The results of obtained measurements are presented as a sequence of time wavelet tomograms where the different wavelet cross-sections in the frequency domain allow to diagnose the state of internal organs based on the spectral characteristics.Conclusion. Digital representation of diagnostic results makes it possible to model health state and to create and exchange patient databases.