bluuebunny/crossref_metadata_2025_split huggingface dataset:
Groundnut Shell Infusion Agar as a Culture Medium for Moulds
Authors: Olufunmilayo Williams, Janet , T. G. Sokari, , Grace Buekor, 
Published: December 2019

Aim: To carry out a Comparative mould analysis using groundnut shell infusion agar (GSA) and potato dextrose agar (PDA), as the control.
Study Design: Laboratory-experimental design was used in this study.
Place and Duration of Study: Soil samples were obtained from three different locations (Garden soil beside Biology Main Laboratory, opposite Faculty of Law and Faculty of Agriculture) in Rivers State University, Port Harcourt Rivers State, Nigeria. The study was carried out for three (3) months at the Microbiology Laboratory, Rivers State University, Port Harcourt.
Methodology: Groundnut Shell Infusion Agar (GSA) was prepared by weighing 28 g of blended gari and 15 g of agar powder into 1L of groundnut shells filtrate. Potato dextrose Agar (PDA), a conventional medium was prepared according to the manufacturer’s specifications. GSA was prepared by weighing 28 g of blended gari and 15 g of agar powder into 1L of groundnut shells filtrate. Potato dextrose agar, a conventional medium was prepared according to the Manufacturer’s specifications.
Results: The mean mould counts from the different locations ranged from 3.7×107 cfu/ml to 7.8×107 cfu/ml on GSA and 3.7×107 cfu/ml to 1.5×109 cfu/ml on PDA following incubation at room temperature (27°c ± 2) for 3-5 days. The moulds identified were Aspergillus niger, Aspergillus flavus, Trichoderma viride, Rhizopus sp. Mucor sp. Botrytis sp. Helminthosporium caryopsidum, and Penicillum sp.
Conclusion: From the results obtained, it showed that GSA could be used successfully for quantitative mould counts and other mycological studies. This would proffer solution to the high cost of conventional media used for moulds as well as agro waste pollution in the environment.
O fascismo, ontem e hoje: denúncias e resistências
Authors: Rodrigues Pereira Maria De Fátima 
Published: December 2019

<p><span>Apresenta-se os autores e seus produtos para esta edição sobre o fascismo. Também, uma apresentação do tema que leva em conta estudos dos autores clássicos sobre o tema, com destaque para Leandro Konder em sua obra- Introdução ao Fascismo, e a Apresentação de Mauro Iasi. Ainda, as considerações de Atílio Boron e Armando Boito sobre o neofascismo. </span></p>
Nanocomposite Polymer Scaffolds Responding under External Stimuli for Drug Delivery and Tissue Engineering Applications
Authors: Mertz Damien , Harlepp Sébastien , Goetz Jacky , Bégin Dominique , Schlatter Guy , Bégin‐Colin Sylvie , Hébraud Anne 
Published: December 2019

AbstractThe blossoming development of nanomaterials and polymer science has opened the way toward new biocompatible scaffolds responding remotely to external stimuli (magnetic field, light, electric field). Such smart scaffolds are envisioned as new implantable tissues displaying multiple therapeutic and imaging functionalities. They hold great promises to achieve a controlled delivery of therapeutics for various diseases, or to ensure a stimuli‐induced cellular response for bone, cardiac, or muscle tissue engineering.
Eliminating Dendrites through Dynamically Engineering the Forces Applied during Li Deposition for Stable Lithium Metal Anodes
Authors: Ren Lingxiao , Wang Aoxuan , Zhang Xinyue , Li Guojie , Liu Xingjiang , Luo Jiayan 
Published: December 2019

AbstractLithium metal anodes are considered the most promising anode for next‐generation high‐energy‐density batteries due to their high theoretical capacity and low electrochemical potential. However, intractable barriers, especially the notorious dendrite growth, severe volume expansion, and side reactions, have obstructed its large‐scale application. Numerous strategies from different points of view are explored to surmount these obstacles. Within these efforts, dynamically engineering the forces applied during the electrochemical process plays a significant role, as they can potentially eliminate the dendrite growth. In this Research News article, the relationship between different kinds of forces and the behavior of Li+/Li during the lithium deposition process is first explicated. Advanced strategies in building dendrite‐free Li anodes through dynamically engineering these forces are also summarized by sorting the Li deposition process into three stages: Li+ transport in electrolyte, Li+ reduction/Li atom surface migration, and Li bulk diffusion. Future perspectives and promising research directions for dendrite control are finally proposed. It is expected that dynamically engineering the forces applied during Li deposition will pave the way for next‐generation high‐energy‐density rechargeable Li metal batteries.
Interfacial energy for solutions of nanoparticles, surfactants, and electrolytes
Authors: Olayiwola Saheed O. , Dejam Morteza 
Published: December 2019

AbstractThe addition of surfactants to modify the surface property of nanoparticles (NPs) from hydrophilic to hydrophobic also enhances their interfacial properties. Several approaches were previously proposed to calculate the surface tension/interfacial tension (IFT) for different systems in the presence of NPs, surfactants, and electrolytes. However, most of these approaches are indirect and require several measured parameters. Therefore, a mathematical model is developed here to calculate the surface tension/IFT for these systems. The developed model takes into account the cohesive energy due to the interaction of the surfactant CH2 groups, the electric double layer effect due to the interaction among the ions of NPs, surfactants, and electrolytes, and the dipole–dipole interaction of NPs and electrolytes. The developed model is compared and validated with the laboratory experimental data in literature. The results reveal further understanding of the mechanisms involved in stabilization of oil/water emulsion in the presence of NPs, surfactants, and electrolytes.
“They Dumped Me Like Trash”: The Social and Psychological Toll of Victimization on Latino Day Laborers' Lives
Authors: Negi Nalini Junko , Siegel Jennifer , Calderon Marilyn , Thomas Emilie , Valdez Avelardo 
Published: December 2019

HighlightsLatino day laborers are vulnerable to crime victimization in new immigrant settlement cities.Victimization led to sociocultural alienation, despair or desesperación, and problem drinking.Findings highlight the intersection of structural vulnerability, violence, and mental health.
Development of a PDEδ‐Targeting PROTACs that Impair Lipid Metabolism
Authors: Winzker Michael , Friese Alexandra , Koch Uwe , Janning Petra , Ziegler Slava , Waldmann Herbert 
Published: December 2019

AbstractThe prenyl‐protein chaperone PDEδ modulates the localization of lipidated proteins in the cell, but current knowledge about its biological function is limited. Small‐molecule inhibitors that target the PDEδ prenyl‐binding site have proven invaluable in the analysis of biological processes mediated by PDEδ, like KRas cellular trafficking. However, allosteric inhibitor release from PDEδ by the Arl2/3 GTPases limits their application. We describe the development of new proteolysis‐targeting chimeras (PROTACs) that efficiently and selectively reduce PDEδ levels in cells through induced proteasomal degradation. Application of the PDEδ PROTACs increased sterol regulatory element binding protein (SREBP)‐mediated gene expression of enzymes involved in lipid metabolism, which was accompanied by elevated levels of cholesterol precursors. This finding for the first time demonstrates that PDEδ function plays a role in the regulation of enzymes of the mevalonate pathway.
Rapid and Large‐Scale Production of Multi‐Fluorescence Carbon Dots by a Magnetic Hyperthermia Method
Authors: Zhu Zhijie , Cheng Rui , Ling Luting , Li Qing , Chen Su 
Published: December 2019

AbstractThe intrinsic low yield of carbon dots (CDs) is a barrier that limits practical application. Now, a magnetic hyperthermia (MHT) method is used to synthesize fluorescent CDs on a large scale (up to 85 g) in one hour (yield ca. 60 %). The reaction process is intensified by MHT since the efficient heating system enhances the energy transfer. CDs with blue, green, and yellow luminescence are synthesized by using carbamide and citrate with three different cations (Zn2+, Na+, K+), respectively. The CDs exhibit bright fluorescence under UV light and show excellent monodispersity and solubility in water. The alternation of photoluminescence (PL) emissions of these CDs is probably due to the difference in particle sizes and surface state. A bar coating technique is used to construct large‐area emissive polymer/CDs films. CDs can insert themselves into the polymer chains by hydrogen bonding and electrostatic interactions. Wound healing efficiency can be enhanced by the Zn‐CDs/PCL nanofibrous scaffold.
Finite‐time reliable dissipative control of neutral‐type switched artificial neural networks with non‐linear fault inputs and randomly occurring uncertainties
Authors: Saravanakumar Thangavel , Nirmala Veerappan Jayakannu , Raja Ramachandran , Cao Jinde , Lu Guoping 
Published: December 2019

AbstractThis work reports the result of finite‐time reliable dissipative control for switched neutral‐type based neural networks subject to input nonlinearities, time‐delay and randomly occurring perturbations. In particular, a novel control model consist of both linear and non‐linear fault inputs is designed for reliable control. In addition, randomly occurring uncertainty caused by stochastic variables satisfying the Bernoulli distribution is considered. Based on Lyapunov stability theory, Jensen's integral inequality technique and average dwell time method, sufficient criteria for finite‐time boundedness of resulting neural networks are obtained. Furthermore, the obtained boundedness theory are enhanced to solve the finite‐time dissipative problem of the considered systems through reliable control against mixed actuator failures. The obtained sufficient conditions are constructed in the form of linear matrix inequalities, which can be facilitated by using some standard numerical Matlab packages. At last, numerical simulations are presented to demonstrate the effectiveness of the considered theory.
An average optimal control approach to the set stabilization problem for boolean control networks
Authors: Gao Jinwu , Lin Sida , Fan Jixiang , Hu Yunfeng 
Published: December 2019

AbstractThis paper addresses the set stabilization problem for deterministic Boolean control networks (BCNs). An optimal control approach is investigated to solve the problems by using the semi‐tensor product of matrices, where a policy iteration algorithm for the set stabilization problem is deduced. Finally, the intervention problem of a cAMP receptor protein is addressed in the framework of the set stabilization problem. The problem is solved to validate the effectiveness of the proposed policy iteration approach for a practical application.
Preparation of a Self‐Supported SiO2 Membrane as a Separator for Lithium‐Ion Batteries
Authors: Kyeremateng Neil Amponsah , Gukte Dion , Ferch Marc , Buk Jan , Hrebicek Tomas , Hahn Robert 
Published: December 2019

AbstractFor the first time, electrophoretic deposition (EPD) has been employed to prepare a self‐supported, inorganic membrane consisting of SiO2 nano‐fibers, as a separator for lithium‐ion batteries. The SiO2 nano‐fibers that were fabricated by a low‐cost force spinning technique were deposited by EPD directly onto LiNi0.8Co0.15Al0.05O2 cathode material. Citric acid charging agent and anhydrous acetone solvent were used. The resulting porosity and tortuosity of the EPD SiO2 separator were 71.42 %, and 1.70, respectively. The slightly higher tortuosity of the EPD‐SiO2‐fiber separator (60 μm) led to a lower rate capability in comparison to commercial GF/A glass fiber separator (260 μm). On the other hand, the latter exhibited lower self‐discharge than the former in full‐cells with a graphite anode; this is proposed to be related to the different purities of the two materials that impart different electronic properties or the presence of 20 wt % PVDF in the EPD‐SiO2 separator. Indeed, the deposited membrane has good characteristics as a battery separator and the EPD process is extremely feasible for the fabrication of miniaturized lithium‐ion batteries on wafer level.
Mitigating skilled labor scarcity through corporate social responsibility program: Lessons from a large company in Indonesia
Authors: Bhinekawati Risa , Bradly Andrew 
Published: December 2019

AbstractScarcity of skilled labor is one of the daunting issues for companies operating in developing economies. This study explores the role of a corporation in solving the issue of skilled labor scarcity by fully financing and operating one of the best manufacturing polytechnics in Indonesia since 1995. It compares a theoretical framework on the linkages between responsible leadership, CSR, social capital, and corporate sustainability with the CSR practices of one of the largest publicly‐listed corporations in Indonesia. This study applies a case study approach to investigate why and how corporate leaders invest in CSR programs that contribute to social capital development and corporate sustainability. It finds that company's long‐term CSR investment in providing higher vocational education in manufacturing has a developed sustainable supply of skilled labors that contributes to the sustainability of the company. The study clarifies the actual relationships between responsible leadership, CSR, social capital, and corporate sustainability in the context of a developing country. The conceptual model from this study can be replicated by corporations operating in emerging markets, where they are expected to not only generate profit but also contribute to the achievement of sustainable development goals.
Insertional tagging of the Scheffersomyces stipitis gene HEM25 involved in regulation of glucose and xylose alcoholic fermentation
Authors: Berezka Krzysztof , Semkiv Marta , Borbuliak Mariia , Blomqvist Johanna , Linder Tomas , Ruchała Justyna , Dmytruk Kostyantyn , Passoth Volkmar , Sibirny Andriy 
Published: December 2019

AbstractAmid known microbial bioethanol producers, the yeast Scheffersomyces (Pichia) stipitis is particularly promising in terms of alcoholic fermentation of both glucose and xylose, the main constituents of lignocellulosic biomass hydrolysates. However, the ethanol yield and productivity, especially from xylose, are still insufficient to meet the requirements of a feasible industrial technology; therefore, the construction of more efficient S. stipitis ethanol producers is of great significance. The aim of this study was to isolate the insertional mutants of S. stipitis with altered ethanol production from glucose and xylose and to identify the disrupted gene(s). Mutants obtained by random insertional mutagenesis were screened for their growth abilities on solid media with different sugars and for resistance to 3‐bromopyruvate. Of more than 1,300 screened mutants, 17 were identified to have significantly changed ethanol yields during the fermentation. In one of the best fermenting strains (strain 4.6), insertion was found to occur within the ORF of a homolog to the Saccharomyces cerevisiae gene HEM25 (YDL119C), encoding a mitochondrial glycine transporter required for heme synthesis. The role of HEM25 in heme accumulation, respiration, and alcoholic fermentation in the yeast S. stipitis was studied using strain 4.6, the complementation strain Comp—a derivative from the 4.6 strain with expression of the WT HEM25 allele and the deletion strain hem25Δ. As hem25Δ produced lower amounts of ethanol than strain 4.6, we assume that the phenotype of strain 4.6 may be caused not only by HEM25 disruption but additionally by some point mutation.
Hollow Structure VS2@Reduced Graphene Oxide (RGO) Architecture for Enhanced Sodium‐Ion Battery Performance
Authors: Qi Haimei , Wang Lina , Zuo Tiantian , Deng Shunlan , Li Qi , Liu Zong‐Huai , Hu Peng , He Xuexia 
Published: December 2019

AbstractInvited for this month's cover picture is the group of Xuexia He from Shaanxi Normal University (China). The cover picture shows the synthesis of VS2 hollow flower spheres and its conductive composite materials. It could provide an important new synthetic avenue for future battery and renewable energy applications. Read the full text of the Article at 10.1002/celc.201901626.
Sidechain Diversification of Grandifloracin Allows Identification of Analogues with Enhanced Anti‐Austerity Activity against Human PANC‐1 Pancreatic Cancer Cells
Authors: Alexander Benjamin E. , Sun Sijia , Palframan Matthew J. , Kociok‐Köhn Gabriele , Dibwe Dya Fita , Watanabe Shiro , Caggiano Lorenzo , Awale Suresh , Lewis Simon E. 
Published: December 2019

AbstractThe natural product (+)‐grandifloracin is a potent “anti‐austerity” agent, able to suppress the ability of various pancreatic cancer cell lines to tolerate conditions of nutrient deprivation. Such anti‐austerity agents represent a promising approach to cancer chemotherapy. Here we report the synthesis and biological evaluation of racemic analogues of grandifloracin bearing diverse sidechains, of which two show enhanced potency in comparison with the natural product. Additionally, several unexpected by‐products containing modifications of the grandifloracin core were isolated, identified and similarly evaluated for biological activity.
Electrostatic Repulsion Controls Efficiency of Cu‐Free Click‐Reaction with Azide‐Modified Semiconductor Quantum Dots
Authors: Ranishenka Bahdan , Ulashchik Egor , Radchanka Aliaksandra , Shmanai Vadim , Artemyev Mikhail 
Published: December 2019

AbstractDetermination of factors influencing the efficiency of conjugation of various molecules with colloidal semiconductor quantum dots (QDs) is an important step toward their biomedical application. We have utilized controlled strain promoted [3+2] azid‐alkyne cycloaddition (SPAAC) as an instrument for studying the influence of charge interaction between QDs and molecules on the efficiency of their conjugation. Azide‐modified polymer‐encapsulated core‐shell CdSe/ZnS QDs, bicyclononyne(BCN)‐modified JOE dye and BCN‐BHQ1(Black Hole Quencher 1)‐modified oligonucleotide duplex were used as model objects for conjugation. Strong surface negative charge of carboxylic QDs was shown to suppress efficient conjugation with negatively charged dsDNA or JOE dye (2′,7′‐dimethoxy‐4′,5′‐dichloro‐fluorescein) molecules. Utilization of zwitter‐ionic QDs with reduced surface charge allows significantly enhance the efficiency of QDs conjugation with dsDNA.
Controllable Synthesis of Two‐Dimensional Molybdenum Disulfide (MoS2) for Energy‐Storage Applications
Authors: Li Xue Liang , Li Tian Chen , Huang Shaozhuan , Zhang Jian , Pam Mei Er , Yang Hui Ying 
Published: December 2019

AbstractLamellar molybdenum disulfide (MoS2) has attracted a wide range of research interests in recent years because of its two‐dimensional layered structure, ultrathin thickness, large interlayer distance, adjustable band gap, and capability to form different crystal structures. These special characteristics and high anisotropy have made MoS2widely applicable in energy storage and harvesting. In this Minireview, a systematic and comprehensive introduction to MoS2, as well as its composites, is presented. It is aimed to summarize the various synthetic methods of MoS2‐based composites and their application in energy‐storage devices (lithium‐ion batteries, sodium‐ion batteries, lithium–sulfur batteries, and supercapacitors) in detail. Based on recent studies, this Minireview provides important and comprehensive guidelines for further study and development efforts in the MoS2in energy‐storage field.
Hydrology and water quality factors driving spatiotemporal analyses of zoobenthos in a pilot city in China
Authors: Zhao Changsen , Pan Xu , Wang Xuelian , Shao Nanfang , Sun Changlei , Zhang Yuan 
Published: December 2019

AbstractIn water ecosystems, zoobenthos are one of the most important communities. Maintenance of healthy zoobenthos community is essential for water ecosystems remediation. Understanding the hydrology and water quality factors that drive the variation of zoobenthos is the priority for water ecosystems remediation. The present study used canonical correlation analysis to select the main habitat factors affecting zoobenthic communities based on field sampling of the river zoobenthos in the first pilot city for the construction of civilized water ecosystems in China—Jinan City. In addition, analysis was performed based on geoscience methods of Global Moran's I and Anselin local Moran's I spatial autocorrelation of main habitats factors. The results show that the key water quality physical factors affecting Jinan City zoobenthic communities were pH and conductivity; the key water quality chemical factors were K+, Na+, and permanganate index; and the key hydrological factor was water depth. The sodium ions and conductivity exhibited significant spatial autocorrelation in all seasons. And the regions exhibiting spatial autocorrelation were generally stable. Moreover, the characteristics of benthic animals are closely related to human activities of domestic sewage discharge in the central and agricultural activities in northern parts of the study area. All methods in this paper can be extended to the researches on other communities, for example, algae, zooplankton, and fish in water ecosystems. The methods and results in the paper can provide significant references for managers to protect and restore degraded water ecosystems in global water.
Transcription factor binding at Ig enhancers is linked to somatic hypermutation targeting
Authors: Dinesh Ravi K. , Barnhill Benjamin , Ilanges Anoj , Wu Lizhen , Michelson Daniel A. , Senigl Filip , Alinikula Jukka , Shabanowitz Jeffrey , Hunt Donald F. , Schatz David G. 
Published: December 2019

AbstractSecondary diversification of the Ig repertoire occurs through somatic hypermutation (SHM), gene conversion (GCV), and class switch recombination (CSR)—three processes that are initiated by activation‐induced cytidine deaminase (AID). AID targets Ig genes at orders of magnitude higher than the rest of the genome, but the basis for this specificity is poorly understood. We have previously demonstrated that enhancers and enhancer‐like sequences from Ig genes are capable of stimulating SHM of neighboring genes in a capacity distinct from their roles in increasing transcription. Here, we use an in vitro proteomics approach to identify E‐box, MEF2, Ets, and Ikaros transcription factor family members as potential binders of these enhancers. ChIP assays in the hypermutating Ramos B cell line confirmed that many of these factors bound the endogenous Igλ enhancer and/or the IgH intronic enhancer (Eμ) in vivo. Further investigation using SHM reporter assays identified binding sites for E2A and MEF2B in Eμ and demonstrated an association between loss of factor binding and decreases in the SHM stimulating activity of Eμ mutants. Our results provide novel insights into trans‐acting factors that dictate SHM targeting and link their activity to specific DNA binding sites within Ig enhancers.