bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid MALDI-TOF MS identification of commercial truffles
Authors: El Karkouri Khalid , Couderc Carine , Decloquement Philippe , Abeille Annick , Raoult Didier 
Published: November 2019

AbstractTruffles are edible mushrooms with similar morphological characteristics, that make it difficult to distinguish between highly prized truffles (such as the Périgord black T. melanosporum) and inexpensive truffles (such as the Asian Black T. indicum). These biological and economic features have led to several misidentifications and/or fraudulent profit in the truffle markets. In this paper, we investigate Matrix-assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS) biotyping to identify 34 commercial fresh truffles from Europe and Asia. The MALDI-TOF MS clustering rapidly distinguished seven Tuber species identified by ITS phylogenetic analysis. The tasty T. melanosporum was clearly differentiated from the Chinese and less expensive truffles. These cheaper mushrooms were marketed as T. indicum but corresponded to a mix of three species. In total, the method confirmed misidentifications in 26% of commercial specimens. Several unknown blind-coded truffles were rapidly identified, with scores >= 2, using the Bruker Biotyper algorithm against MS databases. This study demonstrates that MALDI-TOF MS is a reliable, rapid and cheaper new tool compared with molecular methods for the identification of truffle species and could be used to control frauds in the truffle markets. It could also be useful for the certification of truffle-inoculated seedlings and/or diversity in forest ecosystems.
Acute Kidney Injury in the Outpatient Setting Associates with Risk of End-Stage Renal Disease and Death in Patients with CKD
Authors: Yeh Hung-Chieh , Ting I.-Wen , Huang Han-Chun , Chiang Hsiu-Yin , Kuo Chin-Chi 
Published: November 2019

AbstractCurrent acute kidney injury (AKI) diagnostic criteria are restricted to the inpatient setting. We proposed a new AKI diagnostic algorithm for the outpatient setting and evaluate whether outpatient AKI (AKIOPT) modifies the disease course among patients with chronic kidney disease (CKD) enrolled in the national predialysis registry. AKIOPT was detected when a 50% increase in serum creatinine level or 35% decline in eGFR was observed in the 180-day period prior to enrollment in the predialysis care program. Outcomes were progression to end-stage renal disease (ESRD) and all-cause mortality. Association analyses were performed using multiple Cox regression and coarsened exact matching (CEM) analysis. Among 6,046 patients, 31.5% (1,905 patients) had developed AKIOPT within the 180-day period before enrollment. The adjusted hazard ratios of the 1-year and overall risk of ESRD among patients with preceding AKIOPT compared with those without AKIOPT were 2.61 (95% CI: 2.15–3.18) and 1.97 (1.72–2.26), respectively. For 1-year and overall risk of all-cause mortality, patients with AKIOPT had respectively a 141% (95% CI: 89–209%) and 84% (56–117%) higher risk than those without AKIOPT. This statistical inference remained robust in CEM analysis. We also discovered a complete reversal in the eGFR slope before and after the AKIOPT from −10.61 ± 0.32 to 0.25 ± 0.30 mL/min/1.73 m2 per year; however, the loss of kidney function is not recovered. The new AKIOPT diagnostic algorithm provides prognostic insight in patients with CKD.
Unfall oder Kindesmisshandlung? Differenzialdiagnostik bei Frakturen ohne klare Ursache
Authors: Ajiri Ramona , Koerber Friederike , Banaschak Sibylle , Semler Oliver 
Published: November 2019

ZusammenfassungFrakturen im Kindesalter können nicht nur Folge eines Unfalls, sondern auch einer Kindesmisshandlung sein. Diese Differenzierung ist gerade im Kleinkindalter häufig schwierig, für das weitere Vorgehen und die Zukunft der Patientin oder des Patienten aber von größter Bedeutung. Nach Anamneseerhebung und klinischer Untersuchung dienen Röntgenaufnahmen, Laborwerte und weitere Untersuchungen zur Frakturdiagnose und zum Ausschluss anderer Erkrankungen.
Neuroenhancement in Deutschland am Beispiel von vier Berufsgruppen
Authors: Müller Grit , Freude Gabriele , Kersten Norbert 
Published: November 2019

ZusammenfassungZiel der Studie Diese Studie präsentiert Prävalenzen des pharmakologischen Neuroenhancement in 4 Berufsgruppen. Ziel ist es den Zusammenhang von Neuroenhancement mit psychosozialen Arbeitsbedingungen und psychischer Gesundheit zu untersuchen.Methodik In der Studie zum „Einfluss psychischer Belastungen am Arbeitsplatz auf das Neuroenhancement – empirische Untersuchungen an Erwerbstätigen“ wurden 4166 Beschäftigte aus vier Berufsgruppen (Ärzte, Werbefachleute, Publizisten, Softwareentwickler) in computer-gestützten Interviews befragt. Lebenszeit-, 12-Monats- und 4-Wochen-Prävalenz und korrespondierende Konfidenzintervalle werden berechnet. In Poisson-Regressionsmodellen wurde der Zusammenhang des Neuroenhancements mit psychosozialen Arbeitsbedingungen und den Indikatoren der psychischen Gesundheit geschätzt.Ergebnisse Die Lebenszeitprävalenz des pharmakologischen Neuroenhancement beträgt 8,4%, die 12-Monats-Prävalenz 2,9% und die 4-Wochen-Prävalenz 1,3%. Unter den Berufsgruppen zeigen die Werbefachmänner, -frauen und Softwareentwicklerinnen erhöhte Prävalenzen. Für Männer zeigen sich Zusammenhänge mit den psychosozialen Arbeitsbedingungen Unterstützung durch Kollegen, Rollenklarheit, emotionale Anforderungen und Arbeitsplatzunsicherheit. Symptome des Burnouts und der depressiven Symptomatik korrelieren mit einem Zuwachs im Neuroenhancement.Schlussfolgerungen Im Vergleich zu Stichproben der Allgemein- bzw. Erwerbsbevölkerung, sind die Prävalenzen in den untersuchten Berufsgruppen leicht erhöht. Burnout und depressive Symptomatik erscheinen als potentielle Risikofaktoren oder Folgeerscheinungen des Neuroenhancements zu fungieren.
Facilitating Organizational Change to Accommodate an Inpatient Portal
Authors: Walker Daniel M. , Gaughan Alice , Fareed Naleef , Moffatt-Bruce Susan , McAlearney Ann Scheck 
Published: November 2019

Abstract
Background Patient portals are becoming more commonly used in the hospital inpatient setting. While the potential benefits of inpatient portals are acknowledged, there is a need for research that examines the challenges of portal implementation and the development of best practice approaches for successful implementation.
Objective We conducted this study to improve our understanding of the impact of the implementation of an inpatient portal on care team members in the context of a large academic medical center. Our study focused on the perspectives of nursing care team members about the inpatient portal.
Methods We interviewed care team members (n = 437) in four phases throughout the 2 years following implementation of an inpatient portal to learn about their ongoing perspectives regarding the inpatient portal and its impact on the organization.
Results The perspectives of care team members demonstrated a change in acceptance of the inpatient portal over time in terms of buy-in, positive workflow changes, and acknowledged benefits of the portal for both care team members and patients. There were also changes over time in perspectives of the care team in regards to (1) challenges with new technology, (2) impact of the portal on workflow, and (3) buy-in. Six strategies were identified as important for implementation success: (1) convene a stakeholder group, (2) offer continual portal training, (3) encourage shared responsibility, (4) identify champions, (5) provide provisioning feedback, and (6) support patient use.
Conclusion Inpatient portals are recognized as an important tool for both patients and care team members, but the implementation of such a technology can create challenges. Given the perspectives care team members had about the impact of the inpatient portal, our findings suggest implementation requires attention to organizational changes that are needed to accommodate the tool and the development of strategies that can address challenges associated with the portal.
Total Distal Radioulnar Joint Arthroplasty for Paget's Disease of Bone
Authors: Mullett Patrick H. , Willems Joost , Christensen Thomas J. 
Published: November 2019

Abstract
Background Distal radioulnar joint (DRUJ) and ulnocarpal pathology, such as ulnocarpal impaction, are relatively common causes of ulnar-sided wrist pain. We herein report a rare case of ulnocarpal impaction and DRUJ arthropathy due to Paget's disease of bone (PDB) in the ulna.
Case Description A 65-year-old, right-hand-dominant male was diagnosed with right-sided ulnocarpal impaction secondary to PDB. While diagnosing the cause of this patient's ulnar wrist pain was relatively straightforward, the management of his pain and symptoms was less so. After a thorough discussion with the patient regarding medical versus surgical management, and after presenting all available surgical options, he opted for a total distal radioulnar joint arthroplasty (TDRUJA). At 3-year follow-up, his wrist is pain-free, has excellent functionality, near-normal motion, and he is highly satisfied.
Literature Review Currently, there are no specific recommendations for surgical management of PDB in the ulna, causing ulnocarpal impaction. While resection of the pathologically enlarged ulnar head (Darrach procedure) and the Suavé-Kapandji (SK) procedure are standard surgical treatment options, a major known disadvantage of these procedures is painful ulnar impingement syndrome. TDRUJA, a relatively new treatment option, provides good long-term outcomes with high patient satisfaction and protects from ulnar impingement.
Clinical Relevance Since recommendations are lacking for surgical management of PDB, we propose that the TDRUJA be considered as an effective surgical option for the management of PDB causing ulnocarpal impaction. Furthermore, this can reduce the incidence of ulnar impingement, especially for patients who have pathologically enlarged ulnas that are prone to impingement.
Energetic dependencies dictate folding mechanism in a complex protein
Authors: Liu Kaixian , Chen Xiuqi , Kaiser Christian M. 
Published: November 2019

Significance
Large proteins composed of multiple domains are abundant in all proteomes, but their folding and structural dynamics remain poorly understood. Using single-molecule force spectroscopy, we have defined how stabilizing interfaces among the domains of elongation factor G (EF-G) shape its folding pathway. Contrary to the expectation that multidomain proteins fold sequentially as they emerge from the ribosome, we find that folding cannot be completed until the full protein has been synthesized. This posttranslational folding mechanism results in a propensity for misfolding. It is dictated by an energetic coupling among domains that enables conformational flexibility crucial for EF-G function. EF-G thus provides an example of how distinct biological ends—robust folding and functionally important flexibility—come into conflict during protein biogenesis.
Steering between level repulsion and attraction: broad tunability of two-port driven cavity magnon-polaritons
Authors: Boventer Isabella , Kläui Mathias , Macêdo Rair , Weides Martin 
Published: November 2019

Abstract
Cavity-magnon polaritons (CMPs) are the associated quasiparticles of the hybridization between cavity photons and magnons in a magnetic sample placed in a microwave resonator. In the strong coupling regime, where the macroscopic coupling strength exceeds the individual dissipation, there is a coherent exchange of information. This renders CMPs as promising candidates for future applications such as in information processing. Recent advances on the study of the CMP now allow not only for creation of CMPs on demand, but also for tuning of the coupling strength—this can be thought of as the enhancement or suppression of information exchange. Here, we go beyond standard single-port driven CMPs and employ a two-port driven CMP. We control the coupling strength by the relative phase ϕ and amplitude field ratio δ
0 between both ports. Specifically, we derive a new expression from input–output theory for the study of the two-port driven CMP and discuss the implications on the coupling strength. Furthermore, we examine intermediate cases where the relative phase is tuned between its maximal and minimal value and, in particular, the high δ
0 regime, which has not been yet explored.
Bi ultra-thin crystalline films on InAs(1 1 1)A and B substrates: a combined core-level and valence-band angle-resolved and dichroic photoemission study
Authors: Nicolaï L , Mariot J-M , Djukic U , Wang W , Heckmann O , Richter M C , Kanski J , Leandersson M , Balasubramanian T , Sadowski J , Braun J , Ebert H , Vobornik I , Fujii J , Minár J , Hricovini K 
Published: November 2019

Abstract
The growth of Bi on both the In-terminated (A) face and the As-terminated (B) face of InAs(1 1 1) has been investigated by low-energy electron diffraction, scanning tunnelling microscopy, and photoelectron spectroscopy using synchrotron radiation. The changes upon Bi deposition of the In 4d and Bi 5d
5/2 photoelectron signals allow to get a comprehensive picture of the Bi/InAs(1 1 1) interface. From the early stage the Bi growth on the A face is epitaxial, contrary to that on the B face that proceeds via the formation of islands. Angle-resolved photoelectron spectra show that the electronic structure of a Bi deposit of ≈10 bi-layers on the A face is identical to that of bulk Bi, while more than ≈30 bi-layers are needed for the B face. Both bulk and surface electronic states observed are well accounted for by fully relativistic ab initio calculations performed using the one-step model of photoemission. These calculations are used to analyse the dichroic photoemission data recorded in the vicinity of the Fermi level around the

Γ

¯

point of the Brillouin zone.
Boosting the performance of small autonomous refrigerators via common environmental effects
Authors: Manzano Gonzalo , Giorgi Gian-Luca , Fazio Rosario , Zambrini Roberta 
Published: November 2019

Abstract
We explore the possibility of enhancing the performance of small thermal machines by the presence of common noise sources. In particular, we study a prototypical model for an autonomous quantum refrigerator comprised by three qubits coupled to thermal reservoirs at different temperatures. Our results show that engineering the coupling to the reservoirs to act as common environments lead to relevant improvements in the performance. The enhancements arrive to almost double the cooling power of the original fridge without compromising its efficiency. The greater enhancements are obtained when the refrigerator may benefit from the presence of a decoherence-free subspace. The influence of coherent effects in the dissipation due to one- and two-spin correlated processes is also examined by comparison with an equivalent incoherent yet correlated model of dissipation.
Vesicles with internal active filaments: self-organized propulsion controls shape, motility, and dynamical response
Authors: Abaurrea-Velasco Clara , Auth Thorsten , Gompper Gerhard 
Published: November 2019

Abstract
Self-propulsion and navigation due to the sensing of environmental conditions—such as durotaxis and chemotaxis—are remarkable properties of biological cells that cannot be modeled by single-component self-propelled particles. Therefore, we introduce and study ‘flexocytes’, deformable vesicles with enclosed attached self-propelled pushing and pulling filaments that align due to steric and membrane-mediated interactions. Using computer simulations in two dimensions, we show that the membrane deforms under the propulsion forces and forms shapes mimicking motile biological cells, such as keratocytes and neutrophils. When interacting with walls or with interfaces between different substrates, the internal structure of a flexocyte reorganizes, resulting in a preferred angle of reflection or deflection, respectively. We predict a correlation between motility patterns, shapes, characteristics of the internal forces, and the response to micropatterned substrates and external stimuli. We propose that engineered flexocytes with desired mechanosensitive capabilities enable the construction of soft-matter microbots.
Compensatory climate effects link trends in global runoff to rising atmospheric CO2 concentration
Authors: Yang Hui , Huntingford Chris , Wiltshire Andy , Sitch Stephen , Mercado Lina 
Published: November 2019

Abstract
River runoff is a key attribute of the land surface, that additionally has a strong influence on society by the provision of freshwater. Yet various environmental factors modify runoff levels, and some trends could be detrimental to humanity. Drivers include elevated CO2 concentration, climate change, aerosols and altered land-use. Additionally, nitrogen deposition and tropospheric ozone changes influence plant functioning, and thus runoff, yet their importance is less understood. All these effects are now included in the JULES-CN model. We first evaluate runoff estimates from this model against 42 large basin scales, and then conduct factorial simulations to investigate these mechanisms individually. We determine how different drivers govern the trends of runoff over three decades for which data is available. Numerical results suggest rising atmospheric CO2 concentration is the most important contributor to the global mean runoff trend, having a significant mean increase of +0.18 ± 0.006 mm yr−2 and due to the overwhelming importance of physiological effects. However, at the local scale, the dominant influence on historical runoff trends is climate in 82% of the global land area. This difference is because climate change impacts, mainly due to precipitation changes, can be positive (38% of global land area) or negative (44% of area), depending on location. For other drivers, land use change leads to increased runoff trends in wet tropical regions and decreased runoff in Southeast China, Central Asia and the eastern USA. Modelling the terrestrial nitrogen cycle in general suppresses runoff decreases induced by the CO2 fertilization effect, highlighting the importance of carbon–nitrogen interactions on ecosystem hydrology. Nitrogen effects do, though, induce decreasing trend components for much of arid Australia and the boreal regions. Ozone influence was mainly smaller than other drivers.
Problems of the health status of children and atmospheric air of Gorno-Altaisk under the conditions of increasing transport load
Authors: Chanchaeva E A , Sukhova M G , Sidorov S S 
Published: November 2019

AbstractThe article contains a theoretical study of the problem of the children’ health status and atmospheric air under conditions of increasing traffic load. The children’s body is highly sensitive to the effects of unfavorable environmental factors, susceptible to the pathogenic effects of even subthreshold concentrations of harmful substances, which makes it possible to consider it as a kind of indicator of the state of the environment. The deterioration of the environmental state of the air of Gorno-Altaysk is associated with an increasing traffic load, solid fuel stationary sources, and transboundary pollution coming from the neighboring regions, as well as the location of the city in a mountain valley with poor natural weathering of the air basin. A comprehensive analysis of the health status of the child population in the region (depending on the degree of air pollution) is also conducted.
Experience in studying and assessing hydrological risks in the transboundary conditions of the Selenga River
Authors: Borisova T A 
Published: November 2019

Abstract
The article presents the results of a study of hazardous hydrological phenomena on the example of floods in the transboundary basin of the Selenga River. Based on the analysis of long-term observations of water levels, hazard indicators are identified. This allows to calculate a number of risk indicators. In terms of specific indicators, an integrated risk map has been developed. An assessment of the total economic risk from floods is given, and recommendations for their reduction are proposed.
The influence of the cultivation technology elements on the economic performance of the bare barley grain production
Authors: Rendov N , Gladkikh A , Nekrasova E 
Published: November 2019

Abstract
At the educational and experimental field of the Omsk State Agrarian University, the evaluation of the influence of elements of the cultivation technology of bare barley of the Omsk golozernyy variety 2 (chemical background, sowing time, and seeding rate) on the indicators of the economic efficiency of grain production was carried out. On the background without the use of chemicals, as well as when using herbicides on the background of applying nitrogen fertilizer, the cost of grain per hectare is higher when sowing the crop in the third decade of May. The use of only herbicides (without fertilizer) provided a greater cost of grain at an earlier sowing. Among the studied seeding rates, the maximum cost indicators were observed when sowing 4.5 million viable seeds per hectare. The chemical background also influenced this indicator. The cost of grain per 1 hectare increased by 3,227 rubles with the use of a tank mixture of herbicides, as well as by 4,513 rubles with their complex use with fertilizers (in comparison with the chemical background). At the same time, the strengthening of the chemical background led to an increase in costs per 1 hectare by 1,559 and 3,543 rubles, respectively. An increase in the seeding rate was also accompanied by an increase in costs. The use of herbicides did not lead to a significant change in the cost of grain, but the additional use of nitrogen fertilizer led to its growth. The level of profitability in the version with the use of a tank mixture of herbicides coincided with the option without the use of chemicals (113.1%). The application of nitrogen fertilizer reduced profitability to 81.5% despite the fact that their use was justified by an increase in grain yield. Thus, when considering specific options for the cultivation of bare barley, sowing on May 14-18 with a rate of 4.5 million viable seeds per hectare while using the Puma Super 7.5 herbicides tank mixture, EMV (0.9 l/ha) and Turbo Pruner, MD (75 ml/ha) should be allocated.
An anthropogenic impact on the atmosphere and measures taken to protect it in 1988-2017: data from the industrial Kemerovo region (a historical aspect)
Authors: Kovalevskiy A , Luchnikova Ye , Ilyashenko V 
Published: November 2019

Abstract
The development of industry in the Kemerovo region was accompanied by a significant increase in anthropogenic pressure, including in the form of air pollution, which ultimately leads to a decrease in the quality of life of the local population. Due to environmental legislation adopted at the federal level, a favorable trend in reducing emissions of pollutants into the atmosphere can be traced. However, in practice, the measures taken did not lead to a noticeable improvement in the quality of atmospheric air in large cities of the region. On the positive side, we should note that the environmental legislation and the centralized system for monitoring and controlling the quality of the environment were laid towards the end of the USSR existence. In the Russian period of history, financial incentives for the transition to cleaner production technologies began to be applied. The right to a favorable environment is enshrined in the Constitution of the Russian Federation.