bluuebunny/crossref_metadata_2025_split huggingface dataset:
Klinische epidemiologie: maximale detrusorcontractiekracht gerelateerd aan leeftijd en geslacht
Authors: Rosier Peter F. W. M. , ten Donkelaar Celine S. , de Kort Laetitia M. O. 
Published: January 2020

SamenvattingIn deze cross-sectionele epidemiologische studie is nagegaan wat de relatie is tussen maximale detrusorcontractiekracht en leeftijd bij patiënten die waren verwezen met lower urinary tract symptoms (LUTS). Hiertoe is een retrospectieve analyse uitgevoerd op de resultaten van urodynamisch onderzoek dat werd uitgevoerd bij 1.308 patiënten. De detrusorcontractiekracht gedurende mictie werd vergeleken tussen mannen en vrouwen en tussen verschillende leeftijdsgroepen (range 20–90 jaar). Het betreffen cross-sectionele data van patiënten met LUTS die waren verwezen naar een specialistisch centrum. In hogere leeftijdsgroepen werd er een lagere maximale detrusorcontractie waargenomen. De maximale detrusorcontractiekracht was gemiddeld 30 % minder krachtig bij oudere vrouwen en 12 % minder krachtig bij oudere mannen dan bij jongere vrouwen en mannen. Uit dit onderzoek blijkt dat zowel bij vrouwen als bij mannen met LUTS de maximale detrusorcontractiekracht van de oudere patiënt lager is dan die van de jongere patiënt. Het verschil in maximale detrusorcontractiekracht in relatie tot de leeftijd is groter bij vrouwen dan bij mannen. Deze bevindingen kunnen niet zonder meer gegeneraliseerd worden naar een asymptomatische populatie.
Case report. Progressieve zwelling op de glans penis bij gebruik van een buitenwaarts draagurinaal
Authors: de Barros Hilda A. , Rynja Sybren P. , Noordzij Marinus A. 
Published: January 2020

SamenvattingEen progressieve zwelling op de glans penis is verdacht voor een maligniteit. Differentiaaldiagnostisch kan er ook gedacht worden aan benigne afwijkingen, zoals een fibro-epitheliale poliep (FEP). Een FEP is een tumor die zelden voorkomt op de glans penis. Hieraan lijken chronische lokale druk, inflammatie of eerdere peniele chirurgie ten grondslag te liggen. Klinisch kan het lastig zijn een FEP te diagnosticeren en daarom is het verkrijgen van histologie noodzakelijk. Behandeling bestaat uit excisie. Hier beschrijven wij een zwelling op de glans penis bij een 75-jarige man die een buitenwaarts draagurinaal gebruikt. Hoewel wij aanvankelijk dachten aan een maligniteit, toonde histologisch onderzoek een FEP aan.
The oxidation and hypoglycaemic effect of sorafenib in streptozotocin-induced diabetic rats
Authors: Karbownik Agnieszka , Stachowiak Anna , Urjasz Hanna , Sobańska Katarzyna , Szczecińska Agnieszka , Grabowski Tomasz , Stanisławiak-Rudowicz Joanna , Wolc Anna , Grześkowiak Edmund , Szałek Edyta 
Published: January 2020

Abstract
Background
Diabetes reduces the activity of CYP3A4 and may increase the exposure for the drugs metabolized by the isoenzyme. Sorafenib is a multi-targeted tyrosine kinase inhibitor (TKI), used for the treatment of advanced renal cell carcinoma, hepatocellular carcinoma and radioactive iodine resistant thyroid carcinoma. The TKI undergoes CYP3A4-dependent oxidative transformation, which may be influenced by hyperglycaemia. The aim of the study was to compare the oxidation for sorafenib between healthy and streptozotocin-induced diabetic rats. Additionally, the effect of sorafenib on glucose levels was investigated.

Methods
The rats were assigned to the groups: streptozotocin-induced diabetic (DG, n = 8) or healthy (HG, n = 8). The rats received sorafenib orally as a single dose of 100 mg/kg. The plasma concentrations of sorafenib and its metabolite N-oxide were measured with the validated high-performance liquid chromatography with ultraviolet detection.

Results
The difference between groups in Cmax and AUC0−t values for sorafenib were significant (p = 0.0004, p = 0.0104), and similarly for the metabolite (p = 0.0008, p = 0.0011). Greater exposure for the parent drug and analysed metabolite was achieved in diabetic group. However, the Cmax, AUC0−t, and AUC0−∞ ratios between the metabolite and sorafenib were similar in both groups. The significant reduction of glycaemia was observed only in the diabetic animals.

Conclusion
The findings of the study provide evidence that diabetes significantly influence on the exposition for sorafenib and its metabolite, but similar ratios N-oxide/sorafenib for AUC and Cmax in healthy and diabetic animals suggest that oxidation of the TKI is rather unchanged. Additionally, sorafenib-associated hypoglycaemia was confirmed in diabetic animals.
Gender differences in associations between digital media use and psychological well‐being: Evidence from three large datasets
Authors: Twenge Jean M. , Martin Gabrielle N. 
Published: January 2020

ABSTRACTIntroductionAdolescents spend an increasing amount of time using digital media, but gender differences in their use and in associations with psychological well‐being are unclear.MethodWe drew from three large, representative surveys of 13‐ to 18‐year‐old adolescents in the U.S. and UK (total N = 221,096) examining digital media use in hours per day and several measures of psychological well‐being separately in each of the three datasets.ResultsAdolescent girls spent more time on smartphones, social media, texting, general computer use, and online, and boys spent more time gaming and on electronic devices in general. Associations between moderate or heavy digital media use and low psychological well‐being/mental health issues were generally larger for girls than for boys. Light users of digital media were slightly higher in well‐being than non‐users, with larger differences among boys. Among both genders, heavy users of digital media were often twice as likely as low users to be low in well‐being or have mental health issues, including risk factors for suicide.ConclusionsAssociations between heavy digital media use and low psychological well‐being are larger for adolescent girls than boys.
Management Challenges of Informal Volunteers: The Case of Kermanshah Earthquake in Iran (2017)
Authors: Sharififar Simintaj , Khoshvaghti Amir , Jahangiri Katayoun 
Published: January 2020

AbstractObjectives:Two of the 5 great earthquakes have occurred in Iran between 1990 and 2005. Informal volunteers’ management is a determinant factor in disaster management. This research was conducted to investigate the management challenges of informal volunteers after the Kermanshah earthquake.Methods:The study is qualitative, done by content analysis. Data were gathered by observation and semi-structured interview.Results:Analysis of 12 interviews resulted in 4 main categories (inappropriate dispatch, volunteers’ inefficiency, decrease in volunteers’ incentive, deficiency of welfare services) and 11 subcategories.Discussion:To avoid mistrust and decrease in motivation, proposed actions are: standardize information collection, apply effective communication, create registration networks and accreditation of certificates and expertise, and perform periodic drills.Conclusion:We recommend the start of extracurricular programs and applying potential volunteers within the preparedness phase, and follow-up at the beginning of the response phase. Decrease of motivation to participate in future events needs to be studied more comprehensively.
Distinctive context, divergent pattern: Diffusion of imported management practices in Turkey and implications for late-industrializing countries
Authors: Özen Şükrü , Önder Çetin 
Published: January 2020

AbstractIn this paper, we develop and empirically test hypotheses about the diffusion of imported management practices in Turkey. We emphasize the sociopolitical legitimacy of these practices and present hypotheses as to timing, motivations, and self-promotion. We test these hypotheses with quantitative data on Total Quality Management (TQM) adoption by industrial companies in Turkey. Findings reveal that elite companies adopt TQM earlier on, self-report greater levels of sociopolitically driven legitimacy concerns, and are more likely to participate in a prestigious quality award contest. Overall, our study contributes to diffusion research guided by the new institutional approach by expanding existing models to the diffusion of imported practices across organizations in late-industrializing recipient countries. We particularly show that sociopolitical legitimacy of imported practices that is more characteristic of late-industrializing recipient contexts may generate a divergent pattern of diffusion whereby elite organizations emerge as early adopters and engage in brandishing adoption.
DEGREES OF BRAUER CHARACTERS AND NORMAL SYLOW -SUBGROUPS
Authors: CHEN XIAOYOU , LEWIS MARK L. 
Published: January 2020

Let $p$ be a prime, $G$ a solvable group and $P$ a Sylow $p$-subgroup of $G$. We prove that $P$ is normal in $G$ if and only if $\unicode[STIX]{x1D711}(1)_{p}^{2}$ divides $|G:\ker (\unicode[STIX]{x1D711})|_{p}$ for all monomial monolithic irreducible $p$-Brauer characters $\unicode[STIX]{x1D711}$ of $G$.
ON SUMS OF TWO PRIME SQUARES, FOUR PRIME CUBES AND POWERS OF TWO
Authors: LIU YUHUI 
Published: January 2020

We prove that every sufficiently large even integer can be represented as the sum of two squares of primes, four cubes of primes and 28 powers of two. This improves the result obtained by Liu and Lü [‘Two results on powers of 2 in Waring–Goldbach problem’, J. Number Theory 131(4) (2011), 716–736].
Balloon Eustachian tuboplasty for Eustachian tube dysfunction: report of long-term outcomes in a UK population
Authors: McMurran A E L , Hogg G E , Gordon S , Spielmann P M , Jones S E 
Published: January 2020

AbstractBackgroundBalloon Eustachian tuboplasty is a surgical management option for Eustachian tube dysfunction; it has shown promising results in studies worldwide, but has had limited uptake in the UK. This study reports long-term outcomes for patients offered balloon Eustachian tuboplasty for chronic dilatory and baro-challenge-induced Eustachian tube dysfunction, and describes practical experience gained from its implementation.MethodsBalloon Eustachian tuboplasty was conducted in 25 patients (36 ears) with Eustachian tube dysfunction over three years. Information on presenting symptoms and signs, audiometric findings, tympanometry, and Eustachian Tube Dysfunction Questionnaire-7 scores were recorded pre- and post-operatively with a minimum follow up of one year.ResultsSixteen (64 per cent) of the 25 patients demonstrated symptom resolution after balloon Eustachian tuboplasty according to the Eustachian Tube Dysfunction Questionnaire-7. Fourteen (64 per cent) of the 22 patients with a type B or C tympanogram pre-operatively, had a type A trace post-operatively. Fifteen (75 per cent) of 20 patients with pre-operative conductive hearing loss showed improvement post-operatively, and 11 (50 per cent) of 22 patients with pre-operative middle-ear effusion or tympanic membrane retraction showed resolution.ConclusionBalloon Eustachian tuboplasty can improve subjective and objective measures of Eustachian tube dysfunction, and provide longer-term resolution.
Determinants of successful tracheostomy decannulation in children: a multicentric cohort study
Authors: Schweiger C , Manica D , Lubianca Neto J F , Sekine L , Krumenauer R , Caixeta J A , Maunsell R , Gomes Avelino M 
Published: January 2020

AbstractBackgroundDetermining prognostic factors for the probability of tracheostomy decannulation is key to an adequate therapeutic plan.MethodsA retrospective cohort study of 160 paediatric patients undergoing tracheostomy was conducted. Associations between different parameters and eventual tracheostomy decannulation were assessed.ResultsMean follow-up duration was 27.8 months (interquartile range = 25.5–30.2 months). Median age at tracheostomy was 6.96 months (interquartile range = 3.37–29.42 months), with median tracheostomy maintenance of 14.5 months (interquartile range = 3.7–21.5 months). The overall tracheostomy decannulation rate was 22.5 per cent. Factors associated with a higher probability of tracheostomy decannulation included age at tracheostomy (hazard ratio = 1.11, 95 per cent confidence interval = 1.03–1.18) and post-intubation laryngitis as an indication for tracheostomy (hazard ratio = 2.25, 95 per cent confidence interval = 1.09–4.62). Neurological (hazard ratio = 0.30, 95 per cent confidence interval = 0.12–0.80) and pulmonary (hazard ratio = 0.41, 95 per cent confidence interval = 0.18–0.91) co-morbidities were negatively associated with tracheostomy decannulation. The probability of tracheostomy decannulation decreased significantly with increasing numbers of co-morbidities (p < 0.001).ConclusionAge, post-intubation laryngitis, and number and type of co-morbidities influence tracheostomy decannulation rate in the paediatric population.
The distinctive neural circuitry of complex posttraumatic stress disorder during threat processing
Authors: Bryant Richard A. , Felmingham Kim L. , Malhi Gin , Andrew Elpiniki , Korgaonkar Mayuresh S. 
Published: January 2020

AbstractBackgroundThere is controversy over the extent to which the new International Classification of Diseases (ICD-11) diagnosis of complex posttraumatic stress disorder (CPTSD) is distinct from posttraumatic stress disorder (PTSD). This study aimed to conduct the first investigation of distinctive neural processes during threat processing in CPTSD relative to PTSD.MethodThis cross-sectional functional magnetic resonance study included 99 participants who met criteria for PTSD (PTSD = 32, CPTSD = 28) and 39 trauma-exposed controls. PTSD was assessed with the Clinician-Administered PTSD Scale (CAPS). CPTSD was assessed with an adapted version of the International Trauma Questionnaire. Neural responses were measured across the brain while threat or neutral faces were presented at both supraliminal and subliminal levels.ResultsDuring supraliminal presentations of threat stimuli, there was greater bilateral insula and right amygdala activation in CPTSD participants relative to PTSD. Reduced supraliminal right dorsolateral prefrontal cortex activation and increased subliminal amygdala and insula activation were observed as common dysfunction for both CPTSD and PTSD groups relative to trauma controls. There were no significant differences in terms of subliminal presentations and no differences in functional connectivity. Dissociative responses were positively associated with right insula activation (r = 0.347, p < 0.01).ConclusionsThese results provide the first evidence of distinct neural profiles of CPTSD and PTSD during threat processing. The observation of increased insula and right amygdala activation in CPTSD accords with the proposal that CPTSD is distinguished from PTSD by disturbances in emotion regulation and self-concept.
Prenatal and perinatal factors and risk of eating disorders
Authors: Larsen Janne Tidselbak , Bulik Cynthia M. , Thornton Laura M. , Koch Susanne Vinkel , Petersen Liselotte 
Published: January 2020

AbstractBackgroundAmong the most disabling and fatal psychiatric illnesses, eating disorders (EDs) often manifest early in life, which encourages investigations into in utero and perinatal environmental risk factors. The objective of this study was to determine whether complications during pregnancy and birth and perinatal conditions are associated with later eating disorder risk in offspring and whether these associations are unique to EDs.MethodsAll individuals born in Denmark to Danish-born parents 1989–2010 were included in the study and followed from their 6th birthday until the end of 2016. Exposure to factors related to pregnancy, birth, and perinatal conditions was determined using national registers, as were hospital-based diagnoses of anorexia nervosa (AN), bulimia nervosa, and eating disorder not otherwise specified during follow-up. For comparison, diagnoses of depressive, anxiety, and obsessive-compulsive disorders were also included. Cox regression was used to compare hazards of psychiatric disorders in exposed and unexposed individuals.Results1 167 043 individuals were included in the analysis. We found that similar to the comparison disorders, prematurity was associated with increased eating disorder risk. Conversely, patterns of increasing risks of EDs, especially in AN, with increasing parental ages differed from the more U-shaped patterns observed for depressive and anxiety disorders.ConclusionsOur results suggest that pregnancy and early life are vulnerable developmental periods when exposures may influence offspring mental health, including eating disorder risk, later in life. The results suggest that some events pose more global transdiagnostic risk whereas other patterns, such as increasing parental ages, appear more specific to EDs.
SOCIOLINGUISTIC COMPETENCE AND INTERPRETING VARIABLE STRUCTURES IN A SECOND LANGUAGE
Authors: Kanwit Matthew , Geeslin Kimberly L. 
Published: January 2020

AbstractLearners must develop the ability to vary language according to linguistic and situational factors to produce context-appropriate utterances. Likewise, interpreting the additional meaning conveyed through language variation is essential for successful communication. Nevertheless, research on the interpretation of the variable copulas in Spanish is scarce and we do not know how individual lexical items and patterns of co-occurrence of adjectives with particular copulas influence interpretation. Addressing this void, we compare interpretation of the copulas by native speakers and highly advanced, advanced, and intermediate learners. Participants completed an interpretation task containing the copulas paired with one of nine adjectives, categorized as typically co-occurring withser,estar, or both copulas. The current study contributes to the body of work on communicative competence and advanced L2 proficiency by exploring the development of interpretative abilities of English-speaking learners of Spanish and the extent to which interpretation differs across adjective classes and individual adjectives.
Case marking and word order in Greek heritage children
Authors: CHONDROGIANNI Vasiliki , SCHWARTZ Richard G. 
Published: January 2020

AbstractThis study examined the linguistic and individual-level factors that render case marking a vulnerable domain in English-dominant Greek heritage children. We also investigated whether heritage language (HL) children can use case-marking cues to interpret (non-)canonical sentences in Greek similarly to their monolingual peers. A group of six- to twelve-year-old Greek heritage children in New York City and a control group of age-matched monolingual children living in Greece participated in a production and a picture verification task targeting case marking and (non-)canonical word order in Greek. HL children produced syncretic inflectional errors, also found in preschool monolingual children. In the comprehension task, HL children showed variable performance on the non-canonical OVS but ceiling performance on the SVO conditions, which suggests influence from English. Linguistic factors such as case transparency affected comprehension, whereas child-level factors such as proficiency and degree of (early) use of Greek influenced performance on both modalities.
Advantage and Limitation of Using a Visual Feedback Device during Cardiopulmonary Resuscitation Training
Authors: Kim Chan Woong , Oh Je Hyeok 
Published: January 2020

AbstractIntroduction:Recent cardiopulmonary resuscitation (CPR) guidelines recommend the use of CPR prompt/feedback devices during CPR training because it can improve the quality of CPR.Problem:Chest compression depth and full chest recoil show a trade-off relationship. Therefore, achievement of both targets (adequate chest compression depth and full chest recoil) simultaneously is a difficult task for CPR instructors. This study hypothesized that introducing a visual feedback device to the CPR training could improve the chest compression depth and ratio of full chest recoil simultaneously.Methods:The study investigated the effects of introducing a visual feedback device during CPR training by comparing the results of skill tests before and after introducing a visual feedback device. The results of skill tests from 2016 through 2018 were retrospectively reviewed. The strategy of emphasizing chest compression depth was implemented during the CPR training in 2017, and a visual feedback device was introduced in 2018. The interval between the CPR training and skill tests was seven days. Feedback was not provided during the skill tests.Results:In total, 159 students completed skill tests. Although the chest compression depth increased significantly from 50 mm (42–54) to 60 mm (59–61) after emphasizing chest compression depth (P < .001), the ratio of full chest recoil decreased simultaneously from 100% (100–100) to 81% (39–98; P < .001). The ratio of full chest recoil increased significantly from 81% (39–98) to 95% (77–100) after introducing a visual feedback device (P = .018). However, the students who did not achieve 80% of the ratio of full chest recoil remained significantly higher than in 2016 (1% in 2016, 49% in 2017, and 27% in 2018; P < .001).Conclusions:Although introducing a visual feedback device during CPR training resulted in increasing the ratio of full chest recoil while maintaining the adequacy of chest compression depth, 27% of the students still did not achieve 80% of the ratio of full chest recoil. Another educational strategy should be considered to increase the qualities of CPR more completely.
Examining violence among Not Guilty by Reason of Insanity state hospital inpatients across multiple time points: the roles of criminogenic risk factors and psychiatric symptoms
Authors: Delgado Darci , Mitchell Sean M. , Morgan Robert D. , Scanlon Faith 
Published: January 2020

ObjectiveInstitutional violence in state hospitals is a public health problem that has been severely understudied. Given the personal (ie, staff and patients) and fiscal harms associated with institutional violence, more research into contributing factors for violence is needed. The overarching aim of this study then was to examine associations among psychiatric symptoms, criminal risk factors, and institutional violence.MethodsParticipants were 200 male, female, and transgender forensic mental health inpatients adjudicated Not Guilty by Reason of Insanity and committed to the California Department of State Hospitals. Participants completed a psychiatric symptom measure, and measures of and associated with criminal risk. Institutional violence was recorded from file review and includes physical violence toward staff or patients for 6-months prior to and post patient participation in this study.ResultsAfter adjusting for previous institutional violence, results indicated that psychiatric symptoms were not associated with follow-up institutional violence; however, criminal risk was associated with follow-up institutional violence. Unexpectedly, 2 aspects of criminal risk, antisocial cognitions and associates, were not associated with follow-up institutional violence after adjusting for previous institutional violence. Results also provided a tentative cutoff score on the Self-Appraisal Questionnaire for predicting follow-up institutional violence.ConclusionsThese results have important implications for treating and managing patients at risk for institutional violence, including the need to assess criminogenic risk and leverage treatments that target these risk factors as a best practice approach.
ZERO JORDAN PRODUCT DETERMINED BANACH ALGEBRAS
Authors: ALAMINOS J. , BREŠAR M. , EXTREMERA J. , VILLENA A. R. 
Published: January 2020

AbstractA Banach algebra $A$ is said to be a zero Jordan product determined Banach algebra if, for every Banach space $X$, every bilinear map $\unicode[STIX]{x1D711}:A\times A\rightarrow X$ satisfying $\unicode[STIX]{x1D711}(a,b)=0$ whenever $a$, $b\in A$ are such that $ab+ba=0$, is of the form $\unicode[STIX]{x1D711}(a,b)=\unicode[STIX]{x1D70E}(ab+ba)$ for some continuous linear map $\unicode[STIX]{x1D70E}$. We show that all $C^{\ast }$-algebras and all group algebras $L^{1}(G)$ of amenable locally compact groups have this property and also discuss some applications.