bluuebunny/crossref_metadata_2025_split huggingface dataset:
Total Phenolics, Total Carotenoids and Antioxidant Activity of Selected Unconventional Vegetables Growing in Bangladesh
Authors: Alam Mohammad K. , Rana Ziaul H. , Kabir Nazura , Begum Parveen , Kawsar Mahbuba , Khatun Maksuda , Ahsan Monira , Islam Sheikh N. 
Published: December 2019

Background:
Phenolics and carotenoids are natural antioxidants, which provide health
benefits and protect against degenerative chronic diseases. Utilization and identification of foods
with a high content of these have received greater attention nowadays.

Objective:
The present study reports the total phenolics (TPC) and total carotenoids (TCC) contents
of thirty-two selected unconventional vegetables growing in Bangladesh. In addition, they were also
analyzed for their antioxidant potentials.

Methods:
Folin-Ciocalteu and acetone-petroleum ether extraction followed by spectrophotometric
measurements was employed for TPC and TCC, respectively. The antioxidant capacities of the selected
unconventional leafy vegetables were analyzed using DPPH and Trolox equivalent antioxidant
capacity (TEAC) assays.

Results:
The results revealed that the TPC ranged from 82.41 mg GAE/100 g in Kiokro to 2711.05 mg
GAE/100 g in Mrolapiong whereas the TCC values ranged from 43.05 μg/100 g in Fala to 12863.54
μg/100 g in Roktodrone. The study findings also revealed that the selected plant samples exhibited
high antioxidant capacities. Mrolapiong demonstrated the highest DPPH inhibition (91.31%) and
TEAC (485.55 μmol Trolox/g) value than others. The antioxidant capacities were attributed to phenolic
compounds as there exists a positive correlation between these two variables. Bioactive phytochemicals
are widely distributed in these vegetables, although their amounts vary among the different
types of vegetables.

Conclusion:
The study results suggest that the analyzed vegetables may provide a possible source of
dietary antioxidants and serve as materials for functional foods. Therefore, their production and consumption
must be encouraged in order to preserve biodiversity and prevent their extinction.
MicroRNAs Associated with Overweight and Obesity in Childhood: A Systematic Review
Authors: Flórez Carlos Andrés Rico , García-Perdomo Herney Andrés , Escudero Mildrey Mosquera 
Published: December 2019

Background:
Overweight and obesity prevalence has risen substantially in the last years.
MicroRNAs (miRNAs) are factors that regulate gene expression through binding to a complementary
sequence of mRNA.

Objective:
The objective of this review is to determine the association between the expression of
miRNAs with overweight and obesity in children.

Methods:
A systematic search was carried out in Medline (Ovid), EMBASE, LILACS, and CENTRAL.
Clinical trials, cohort studies, cases and controls, and cross-section studies were included.
Quasi-experimental, prognostic studies, animal experiments, in silico studies, and studies on the adult
population were excluded.

Results:
Seven studies (684 children) were included in this review. Three hundred and sixty-one
children had obesity/overweight and 323 had normal weight. 40.64% (278) of the children were
boys. The classification of obesity was inconsistent between the studies with several classifications
used. A total of 65 miRNAs were reported to be associated with obesity and overweight; at least two
studies reported miR-122, miR-122-5p, miR-15b, miR15b-5p, miR191-5p, miR-222, miR-222-3p,
miR 486, miR-486-3p and miR-486-5p. Blood samples were the most common samples used to
measure miRNAs, and the approaches to select miRNAs were diverse, with four articles performing
high-throughput techniques (sequencing and microarrays) before the validation of the miRNAs associated
with obesity. Pathway analysis of the repeated miRNAs showed that they were involved in the
regulation of metabolic and signaling pathways, including fatty acid metabolism.

Conclusion:
miRNAs are potential biomarkers of the development of pathologies, such as obesity. It
was found a heterogeneous group of these molecules was associated with obesity in children. miR-
15b-5p, miR-486-5p, and hsa-miR-122-5p were considered as good candidates for obesity biomarkers.
TOPICS IN MEDICAL EDUCATION ELECTIVE BLOCK: A STUDY USING DELPHI METHOD
Authors: Geraldo Geraldo , Rukmini Elisabeth 
Published: December 2019

Background: Problematic practices performed by doctors and clinical phase students often be found in the workplace settings. Common problems related to team working is the highest rated problems. To overcome this problem, we designed an elective course, Medical Education block (ME) and have implemented the course since 2014. This study aimed to find topics in ME which were meaningful toward medical student’s practices. Methods: A Delphi method were utilized. The experts were the subjects themselves to acknowledge that they were the participants of the ME block, other elective blocks, and clerkship. There were 21 respondents consisted of 2012, 2013 and 2014 bathces. All the subjects were in their clerkship or at the end of their education. They were divided into two groups: who enrolled in ME (n=10), and other blocks (n=11). The questionnaire was consisted of three parts. The first part listed 5 main topics with responses of agree/disagree. The second part listed the same topics, but subjects needed to response the weight on each topic. The last part listed 27 topics in ME Block that might or might not relate to clerkship. Responses were given in agree/disagree. Results: Using two-rounded Delphi method, we found the average of rate of agreement (roa) on the first round was 88% and the second was 81%. There were only 2 statements of the second part which had roa >70%. Thus, the second part went to the 2nd round together with the 3 statements of the third parts. Finally, there were only 2 statements of the second parts achieved roa and there were 2 topics left undecided of the third part. Conclusion: Few topics which were proven useful for medical students were personal education, medical education research, and professionalism. Keywords: practices, medical education, elective course
THE UNDERGRADUATE MEDICAL STUDENTS’ PITFALLS IN EYE EXAMINATION STATION OF OBJECTIVE STRUCTURED CLINICAL EXAMINATION
Authors: Doni Widyandana , Agni Angela Nurini , Supartoto Agus 
Published: December 2019

Background: High prevalence of eye disorders in Indonesia requires medical doctors to be skillful and well trained in ophthalmologic examination. Undergraduate medical students usually start their clinical simulation practice and ophthalmology assessment in a safe learning environment. Skill laboratory as the learning facility should be evaluated and improved regularly. This study aimed to evaluate student’s pitfalls in the eyes OSCE station. Methods: Descriptive analytic study involving Objective Structured Clinical Examination (OSCE) eye examination station score from 1st - 4th year undergraduate medical students batch 2010 in Faculty of Medicine, Universitas Gadjah Mada, Indonesia (n=516). All checklists’ scores were analyzed based on particular sub-scales in every examination topic to explore the most pitfalls made by students in eye examination station during OSCE. Results: The order average value of each subscale in OSCE are: Doctor patient interaction (88.42), History taking skills (82.44), Professionalism (76.43), Physical Examination (74.62), Diagnosis (60.68), Management of Pharmacotherapy (54.70). The percentage of failed-students (scores <70) in 1st-4th year OSCE based on topics skills were Year 1: Visual field (5.08%), Visual acuity (14.21%), Anterior Segment (2.54%). 2nd year: IOP by palpation (24.38%), Visual acuity (9.38%), Anterior Segment (29.38%). Year 3: visual field (4.94%), IOP by palpation (2.47%), Visual acuity (12.35%), Anterior Segment (7.41%), Posterior Segment (22.22%). Year 4: Comprehensive eye exam (17.95%). Conclusions: Students mostly challenged in the skills of diagnosis establishment and pharmacological management. The highest number of failed students in each year OSCE vary from each year. 1st year failed most at visual acuity examination, 2nd year was anterior segment examination and 3rd year was posterior segment examination. Those three skills need to be enhanced systematically. Keywords: OSCE, pitfall pattern, eye examination, undergraduate students, skill laboratory
Reading over McLuhan’s Shoulder
Authors: Peters John Durham 
Published: December 2019

Background This article1 presents a reworked keynote address given at the “Many McLuhans” conference held at the University of Toronto in September 2018 on the occasion of UNESCO recognizing Marshall McLuhan’s library as part of its Memory of the World program.Analysis The article explores McLuhan as a reader and suggests that his greatest work might have been what he read rather than what he wrote. Conclusion and implications The library, as a genre, is one of the great media forms of modernity and antiquity and a marker of the fragility and majesty of the things that humans do with their large brains. Contexte Cet article consiste en la révision d’un discours principal donné au colloque « Many McLuhans » tenu en septembre 2018 à l’Université de Toronto, à l’occasion de la reconnaissance de la bibliothèque de Marshall McLuhan par l’UNESCO dans le contexte de son programme Mémoire du monde.Analyse L’article explore McLuhan en tant que lecteur et suggère que sa plus grande œuvre consiste en ce qu’il a lu plutôt qu’en ce qu’il a écrit.Conclusions et implications La bibliothèque, en tant que genre, est une des grandes formes médiatiques de l’Antiquité et de la modernité et une instance de la fragilité et de la majesté de ce que font les humains avec leurs grands cerveaux.
McLuhan and Posthumanism: Extending the Techno-Animal Embrace
Authors: Berland Jody 
Published: December 2019

Background This article builds on McLuhan’s medium theory to address the undertheorized role of animals as mediators in network cultures.Analysis McLuhan’s medium theory aligns with and to some extent anticipates contemporary discussion about posthumanist thought that recognizes that human perception and experience are shaped by and extended through non-human tools and connections. Both digital culture and the endangered status of the natural world now call upon us to elaborate less anthropocentric concepts of mediation to understand our interdependence with the non-human world.Conclusion and implications Using as illustration various moments of media change, including early coins and the first cat videos, this article argues that the proliferation of animal imagery is significant not only in the affective management of digital practices and investments, but more broadly in the management of cultural and ecological risk.Contexte Cet article se fonde sur la théorie des médias de Marshall McLuhan afin de traiter du rôle sous-théorisé des animaux en tant que médiateurs dans les cultures du réseau.Analyse La théorie des médias de McLuhan s’aligne avec—et dans une certaine mesure anticipe—les discussions contemporaines sur la pensée post-humaniste reconnaissant que des connections et outils non-humains contribuent à former et à prolonger la perception et l’expérience humaines. La culture numérique et le statut menacé du monde naturel exigent que nous élaborions des concepts sur la médiation qui soient moins anthropocentriques afin de mieux comprendre notre interdépendance avec le monde non-humain.Conclusion et implications Cet article se rapporte à divers changements médiatiques, y compris la création de certaines pièces de monnaie anciennes et les premières vidéos sur les chats, pour soutenir que la prolifération d’imagerie animale est importante, non seulement dans la gestion affective de pratiques et d’investissements numériques, mais aussi plus généralement dans la gestion de risques culturels et écologiques.
O léxico como um recurso linguístico para a produção de significado no texto: um estudo de caso com protocolos de investigação (The lexis as a linguistic resource for the production of meaning in texts: a case study with probe protocols)
Authors: Figueredo Giacomo Patrocinio , Rodrigues Júlia Santos Nunes , Oliveira Francieli Silvéria , Alves Ricardo José 
Published: December 2019

Este artigo tem por objetivo investigar a complementaridade dos papéis desempenhados pelo o léxico e a gramática na organização do texto. Toma-se como base a Linguística Sistêmico-Funcional, uma vez que esta postula uma relação de interdependência entre léxico e gramática. Pretendendo contribuir com o conhecimento acerca do papel que o léxico desempenha na organização geral da língua, este artigo promove um estudo de caso no qual um corpus composto por artigos acadêmicos e matérias jornalísticas a respeito do Diabetes Mellitus foi compilado. Em seguida, foram aplicados no corpus dois protocolos de investigação lexical. Os resultados apontaram que mesmo mantendo o domínio experiencial, construído pelo léxico, as escolhas sistêmicas nos dois processos sociossemióticos foram diferentes. Além disso, para um item ser considerado lexical é necessário que ele possa ser generalizado através do estabelecimento de relações taxonômicas de identificação, classificação e generalização. PALAVRAS-CHAVE: Léxico. Protocolos de investigação. Linguística sistêmico-funcional.
JAVA Revises Peer-Reviewer Guidelines
Authors: Richardson Deborah , Vesely Tom , Costa Nancy , Dean Stephanie , Moureau Nancy , Wise Marcia 
Published: December 2019

Abstract
When a manuscript is submitted to the Journal of the Association for Vascular Access (JAVA). it undergoes a stringent review process by two to three peer reviewers who are experts in the field of vascular access. To ensure that authors are provided the most helpful review possible, JAVA's Publications Committee felt that an assessment of reviewer guidelines used in the past several years was in order. Therefore, a small taskforce of members from JAVA's Publications Committee reviewed the existing guidelines and, over a three-month period, updated them. The goal of these revised guidelines is for peer reviewers to be able to provide authors with highly detailed and informative reviews. For reviewers, the new guidelines will clarify the type of information required in a review, which in turn, will generate more detailed feedback for the authors. Both authors and JAVA reviewers will find these new guidelines important because they will ultimately improve the quality of the manuscripts published in the Journal.
Central Venous Catheter Tip Placement: Determination of Posterior Malposition—A Case Study
Authors: Markovich Mary B. 
Published: December 2019

Abstract
Methods for determining central venous catheter (CVC) tip placement vary among facilities. In most institutions, a single-view, anterior chest radiograph is used to visualize and evaluate the CVC catheter for malposition and/or position of the catheter tip. However, this method does not identify the posterior malposition of the catheter tip, which, on the anterior view, may appear correctly placed. In this article, the author (a) identifies the need for double-view chest radiographs for accurate determination of CVC tip placement and (b) emphasizes the importance of expertise of vascular access practitioners in the determination of catheter-tip placement and the identification of malposition and complication of CVC placement.
Plasma Lipidome and Prediction of Type 2 Diabetes in the Population-Based Malmö Diet and Cancer Cohort
Authors: Fernandez Céline , Surma Michal A. , Klose Christian , Gerl Mathias J. , Ottosson Filip , Ericson Ulrika , Oskolkov Nikolay , Ohro-Melander Marju , Simons Kai , Melander Olle 
Published: December 2019

OBJECTIVEType 2 diabetes mellitus (T2DM) is associated with dyslipidemia, but the detailed alterations in lipid species preceding the disease are largely unknown. We aimed to identify plasma lipids associated with development of T2DM and investigate their associations with lifestyle.RESEARCH DESIGN AND METHODSAt baseline, 178 lipids were measured by mass spectrometry in 3,668 participants without diabetes from the Malmö Diet and Cancer Study. The population was randomly split into discovery (n = 1,868, including 257 incident cases) and replication (n = 1,800, including 249 incident cases) sets. We used orthogonal projections to latent structures discriminant analyses, extracted a predictive component for T2DM incidence (lipid-PCDM), and assessed its association with T2DM incidence using Cox regression and lifestyle factors using general linear models.RESULTSA T2DM-predictive lipid-PCDM derived from the discovery set was independently associated with T2DM incidence in the replication set, with hazard ratio (HR) among subjects in the fifth versus first quintile of lipid-PCDM of 3.7 (95% CI 2.2–6.5). In comparison, the HR of T2DM among obese versus normal weight subjects was 1.8 (95% CI 1.2–2.6). Clinical lipids did not improve T2DM risk prediction, but adding the lipid-PCDM to all conventional T2DM risk factors increased the area under the receiver operating characteristics curve by 3%. The lipid-PCDM was also associated with a dietary risk score for T2DM incidence and lower level of physical activity.CONCLUSIONSA lifestyle-related lipidomic profile strongly predicts T2DM development beyond current risk factors. Further studies are warranted to test if lifestyle interventions modifying this lipidomic profile can prevent T2DM.
PENGARUH BAURAN PEMASARAN TERHADAP KEPUASAN PELANGGAN PADA RESTORAN LAMUN OMBAK KOTA PADANG
Authors: Manvi Kurnia Illahi 
Published: December 2019

Padang Restaurant business today shows a relatively rapid development, proven by the increasing number of Padang Restaurants in Indonesia. This indicates that the intensity of competition in the restaurant business is getting stronger. The tendency of people or customer eating in the Padang restaurant is considered to have its own taste, which is able to provide a place in the hearts of food lovers. This kind of opportunity is used by the Lamun Ombak Restaurant to provide a service model that is really needed by the surrounding community. The variety of products and service systems for the Lamun Ombak Restaurant, in fact, can relatively influence purchasing decisions so that maximum customer satisfaction can be created. This study aims to determine the effect of the marketing mix on customer satisfaction at Lamun Ombak Restaurant. The research design used surveys and research methods which are associative methods. The research instrument uses a Likert scale, and the analysis technique uses multiple linear regressions, considering the model is composed of a number of causal relationships between latent variables.
Keywords: marketing mix, restaurant, customer satisfaction.
ANALISIS POTENSI KAWASAN PESISIR PANTAI KOTA PADANG SEBAGAI WISATA OLAHRAGA MARATON BERSKALA INTERNASIONAL
Authors: Pramudia Heru 
Published: December 2019

Lately, the coastal city of Padang has been improving and being promoted. One of the efforts that can advance tourism is through the introduction and development of national and international sports tourism such as marathons. Marathon is one of the popular sports, such as the New York City Marathon, Parias Marathon, Asia Tokyo Marathon, Tour De France, Bali sailboat competition. This research includes mapping the potential of international scale marathon tourism, how to analyze the potential of sports tourism and the obstacles in the development of sports tourism in the city of Padang. In this study, researchers observed coastal locations that have the potential to develop marathon tourism tourism by looking at the level of tourist development, information on potential locations obtained from informants / informants, these locations have been tested and used for marathon tourism.
The internal potential of this marathon sports tour is "high potential" to be held with the quality of marathon tourist attractions and tracking conditions are very good. External potentials include accessibility; object support facilities; complementary facilities, and object development support, this is "high potential" for holding International-scale Marathon Tourism activities. Marathon tourism can be held with a variety of competition criteria by participating in the role of the surrounding community; provide packages offering attractive activities of all ages, clear supporting facilities information; widely introduce to the public a series of marathon tourism activities.
The 10K track with diverse contours offers sports and tourism experiences; several narrow road spots so as not to be filled by vehicles or the activities of the local community; the track route is a public area, the number of alternative routes can be used for road transfers; the field committee is able to coordinate public vehicle traffic during the event. Alternative roads and parking areas to be managed by involving local communities so that activities run smoothly. The government helps manage community business activities; avoid illegal payments so as to provide comfort for tourists; parking area prepared to anticipate the emergence of wild parking; education and sanctions for people who do not maintain cleanliness and sanction if there is extortion. Promotion of tourism and sports activities to be further intensified through all media publications; provide opportunities for local EOs and professional EOs to collaborate in the learning process; promotion and clear and mutually beneficial cooperation relationships.
ANALISIS SEMIOTIKA PADA KUMPULAN PUISI BANTALKU OMBAK SELIMUTKU AINGIN KARYA D. ZAWAWI IMRON
Authors: Hidayat Ryan 
Published: December 2019

Tujuan artikel ini untuk menganalisis kajian semiotika pada kumpulan puisi Bantalku Ombak Selimutku Angin Karya D. Zawawi Imron. Dalam mengapresiasi puisi sering kali menyebabkan kecenderungan pendekatan dalam mengkaji karya sastra. Kecenderungan pertama akan memperhatikan kesadaran dan ketidaksadaran pengarang, serta seluruh lingkungan sosial, politik, dan intelektualnya sebagai penentu makna puisi. Kecenderungan kedua beranggapan bahwa makna puisi yang sesungguhnya merupakan hasil atau akibat dari interaksi antara pembaca dan puisi yang dibaca. Kata Kunci : Analisis, Semiotika, Puisi