bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metastatic pheochromocytoma to the pancreas diagnosed by endoscopic ultrasound‐guided fine needle aspiration: A case report and review of literature
Authors: Yang Shanna X. , Dogra Vikram S. , Kothari Truptesh H. , Reyes Maria Cecilia D. 
Published: October 2019

AbstractPancreatic pheochromocytomas are rare and typically diagnosed by local resection. We present the first reported case of metastatic pheochromocytoma to the pancreas diagnosed by endoscopic ultrasound‐guided fine needle aspiration (EUS‐FNA) and cytology. A 67‐year‐old female presented with 2 to 3 months of abdominal pain. A CT scan showed a large mass in the head of the pancreas engulfing the superior mesentery artery and vein, along with a large mass in the left adrenal gland. An EUS‐FNA was performed on the pancreatic mass with a 22‐gauge needle, yielding an adequate sample. Papanicolaou stain, Diff‐Quik, and cell block showed loosely cohesive clustered tumor cells and singly dispersed pleomorphic naked tumor nuclei with anisonucleosis and cytoplasmic vacuolization. Tumor cells stained positive for synaptophysin, chromogranin A, and CD56 and negative for CK AE1/3 and CK AE1/3‐CAM5.2 cytokeratin cocktail. Because of cytokeratin negativity, diffusely positive neuroendocrine markers, and the presence of an adrenal mass, a metastatic malignant pheochromocytoma was suspected. Additional testing showed elevations in plasma metanephrines and normetanephrines, urine metanephrine‐to‐creatinine and normetanephrine‐to‐creatinine ratios, and serum chromogranin A. An iodine123‐metaiodobenzylguanidine (MIBG) scan was obtained, which showed significantly increased MIBG uptake in the left adrenal lesion. A diagnosis of metastatic malignant pheochromocytoma was made. Surgical oncology was consulted, who recommended against resection of the adrenal mass in favor of outpatient management. Metastatic pheochromocytoma to the pancreas are rare tumors that may yield diagnostic material by EUS‐FNA with a 22‐gauge needle.
Unusual trifecta of infections, aspiration, and metastatic prostatic adenocarcinoma in a bronchoalveolar lavage specimen
Authors: Wang Brant G. , Mani Haresh , Wang Zoe Q. , Nayer Zacharia , Khan Jawad 
Published: October 2019

AbstractBronchoalveolar lavage (BAL) is a useful procedure to evaluate lung infiltrates in order to identify infection, foreign body aspiration, and neoplasms. However, it is indeed unusual to find all three in the same sample. We report such a case in a 68‐year‐old male with a history of metastatic prostate adenocarcinoma and longstanding chronic obstructive pulmonary disease who presented with features of pneumonia. BAL revealed Aspergillus and parainfluenza infections, food particle aspiration pneumonia, as well as metastatic prostatic adenocarcinoma. The food particles were initially confused for yeast infection, but we finally identified them as nut products. This may be the first documented case of nut product aspiration diagnosed on BAL. The potential pitfalls that may complicate the evaluation are also discussed.
A preliminary survey of medium and large‐sized mammals from Lebu Natural Protected Forest, Southwest Showa, Ethiopia
Authors: Qufa Chala Adugna , Bekele Afework 
Published: October 2019

AbstractThis study was conducted to determine the species composition and diversity of medium and large‐sized mammals from Lebu Natural Protected Forest, Ethiopia. Surveys were conducted to record mammals through direct observation and indirect evidence from three habitat types, namely: natural forest, bushland, and riverine forest. A total of 15 mammalian species were recorded. The species recorded were Papio anubis, Chlorocebus aethiops, Tragelaphus scriptus, Canis aureus, Crocuta crocuta, Panthera pardus, Procavia capensis, Colobus guereza, Sylvicapra grimmia, Orycteropus afer, Helogale parvula, Hystrix cristata, Lepus fagani, Potamochoerus larvatus, and Phacochoeus africanus. A total of 223 records of observations were compiled. About 74% of these records (N = 167) were obtained from direct sight, whereas the rest was recorded through indirect evidence. The dominant order recorded was order Primates (57.4%) followed by order Artiodactyla (17.5%) while the least record was order Lagomorpha (1.34%). The species richness varied across the stratified habitat types. However, there is no significant difference in Shannon–Wiener Index values between the habitat types. The species diversity of the study area was H′ = 2.119. The present study area is of great potential area for the conservation of the species. Long‐term detailed studies should be carried out for effective conservation and management initiatives in the study area.
Novel Fe2O3@CeO2 Coreshell‐based Electrochemical Nanosensor for the Voltammetric Determination of Norepinephrine
Authors: Mazloum‐Ardakani Mohammad , Alizadeh Zahra , Sabaghian Fariba , Mirjalili BiBiFatemeh , Salehi Naeimeh 
Published: October 2019

AbstractA new selective carbon paste electrode (CPE), was applied as an electrochemical sensor for the detection of norepinephrine (NOE). The sensor was modified with 6‐amino‐4‐(3,4‐dihydroxyphenyl)‐3‐methyl‐1,4‐dihydropyrano[2,3‐c],pyrazole‐5‐carbonitrile (ADPC) assisted Fe2O3@CeO2 coreshell nanoparticles (CNs) synthesized by simple method. To identify the redox properties of the modified electrode, and to examine its electrochemical properties, cyclic voltammetry (CV), chronoamperometry and differential pulse voltammetry (DPV) were conducted. Through electrochemical investigations, the coefficient of electron transfer between ADPC and the CNs/CPE (i. e. carbon paste electrode which was modified with CNs), the apparent charge transfer rate constant (ks), and the diffusion coefficient (D) were calculated. The NOE oxidation occurred at the optimum pH of 7.0 and a potential that was about 235 mV less positive than that of the unmodified carbon paste electrode. The interaction between the two metals in the Fe2O3@CeO2 coreshell led to an increase in the surface area and, consequently a sharp increase in the current. The differential pulse voltammogram of NOE showed two linear dynamic ranges an excellent detection limit (3σ) of 40 nM. In addition, NOE, AC and Trp were simultaneously determined at the modified electrode. Finally, NOE was quantitated in a number of real samples.
Is food addiction a predictor of treatment outcome among patients with eating disorder?
Authors: Romero Xandra , Agüera Zaida , Granero Roser , Sánchez Isabel , Riesco Nadine , Jiménez‐Murcia Susana , Gisbert‐Rodriguez Montserrat , Sánchez‐González Jéssica , Casalé Gemma , Baenas Isabel , Valenciano‐Mendoza Eduardo , Menchon Jose M. , Gearhardt Ashley N. , Dieguez Carlos , Fernández‐Aranda Fernando 
Published: October 2019

AbstractObjectivesThe study aimed to examine whether food addiction (FA) was associated with greater severity in both binge eating disorders (BED) and bulimia nervosa and, therefore, to determine if FA was predictive of treatment outcome.MethodSeventy‐one adult patients with bulimia nervosa and BED (42 and 29, respectively) participated in the study. FA was assessed by means of the Yale Food Addiction Scale.ResultsThe results confirmed a high prevalence of FA in patients with binge disorders (around 87%) and also its association with a greater severity of the disorder (i.e., related to an increased eating psychopathology and greater frequency of binge eating episodes). Although FA did not appear as a predictor of treatment outcome in general terms, when the diagnostic subtypes were considered separately, FA was associated with poor prognosis in the BED group. In this vein, FA appeared as a mediator in the relationship between ED severity and treatment outcome.DiscussionsOur findings suggest that FA may act as an indicator of ED severity, and it would be a predictor of treatment outcome in BED but not in BN.
SD‐MAC: Design and evaluation of a software‐defined passive optical intrarack network in data centers
Authors: Cai Yueping , Yao Zongchen , Li Tianchi , Luo Sen , Zhou Li 
Published: October 2019

AbstractWith rapid development of cloud computing services, traffic in data centers (DCs) increases dramatically. Top‐of‐rack Ethernet switches dominate network cost and energy consumptions in DCs. Optical switching technologies have been introduced into DC networks to increase switching capacity and to reduce energy consumption. However, how to design high‐performance optical intrarack networks is still a great challenge. This paper presents a software‐defined passive optical intrarack network (SD‐POIRN) based on optical coupler fabrics. The data plane of SD‐POIRN is a broadcast‐and‐select optical network combining wavelength division multiplexing and time division multiplexing technologies. The control plane of SD‐POIRN has a centralized rack controller for scheduling intrarack data transmissions. This paper proposes a software‐defined media access control (SD‐MAC) protocol for SD‐POIRN. The SD‐MAC utilizes dynamic transmission and receiving server grouping methods and max‐min fair share bandwidth allocation algorithms to dynamically allocate bandwidth among servers in an efficient and fair manner. Network performance evaluation results show that, when the offered load is high, the proposed SD‐MAC protocol effectively increases network throughput and reduces average packet delay compared with previous works.
Pore size matching up: A novel insight into cotton textile aromatic finishing
Authors: Liu Xuan , Huang Liyun , Chen Huayan , Qian Michael C. , Ji Hongbing 
Published: October 2019

AbstractAromatic reservation is one of the key evaluation index of textiles which be finished with fragrant micro‐/nanocapsules, and some researches discover that when the fragrant micro‐/nanocapsules penetrating into the spacing of textiles, the resulting aromatic textiles own much better carrying capability of micro‐/nanocapsules. Based on these phenomena, hence in our research, the matching up between pore sizes of cotton textile and sizes of fragrant micro‐/nanocapsules is investigated systematically in order to reveal the size effect on the durability of fragrant micro‐/nanocapsules in cotton textile. Firstly, the pore sizes of cotton textile are analyzed by three different techniques: 3D X‐ray microscopy (Micro‐CT), nitrogen adsorption/desorption method (BET), and mercury intrusion porosimetry (MIP) technique. Based on the pore sizes obtained from MIP technique, citronella oil/chitosan micro‐/nanocapsules with three corresponding sizes are prepared and then applied on cotton textiles through vacuum impregnation process. The pore sizes of cotton textile measured by MIP technique decrease from before finishing to after finishing with nanocapsules, which states that nanocapsules are entrapped inside the pores of cotton textile. Finally, the washing durability of aromatic cotton textile is evaluated by headspace–solid‐phase microextraction (HS‐SPME) technique combining with GC‐MS which can keep the fragrant micro‐/nanocapsules unbroken to simulate the “real” sniffing environment. The results show that aromatic cotton textile treated with nanocapsules possesses much better washing durability, which is met up with the results of pore size measurements: More nanocapsules are penetrating into the spacing of cotton textile fibers even the pores in fibers.
Numerical simulation of compressible multifluid flows using an adaptive positivity‐preserving RKDG‐GFM approach
Authors: Ge Liang , Zhang A‐Man , Zhang Zhong‐Yu , Wang Shi‐Ping 
Published: October 2019

SummaryThe Runge‐Kutta discontinuous Galerkin method together with a refined real‐ghost fluid method is incorporated into an adaptive mesh refinement environment for solving compressible multifluid flows, where the level set method is used to capture the moving material interface. To ensure that the Riemann problem is exactly along the normal direction of the material interface, a simple and efficient modification is introduced into the original real‐ghost fluid method for constructing the interfacial Riemann problem, and the initial conditions of the Riemann problem are obtained directly from the solution polynomials of the discontinuous Galerkin finite element space. In addition, a positivity‐preserving limiter is introduced into the Runge‐Kutta discontinuous Galerkin method to suppress the failure of preserving positivity of density or pressure for the problems involving strong shock wave or shock interaction with material interface. For interfacial cells in adaptive mesh refinement, the data transfer between different grid levels is achieved by using a L2 projection approach along with the least squares fitting. Various numerical cases, including multifluid shock tubes, underwater explosions, and shock‐induced collapse of a underwater air bubble, are computed to assess the capability of the present adaptive positivity‐preserving RKDG‐GFM approach, and the simulated results show that the present approach is quite robust and can provide relatively reasonable results across a wide variety of flow regimes, even for problems involving strong shock wave or shock wave impacting high acoustic impedance mismatch material interface.
Reduction of acute mild stress corticosterone response and changes in stress‐responsive gene expression in male Balb/c mice after repeated administration of a Rhodiola rosea L. root extract
Authors: Dinel Anne‐Laure , Guinobert Isabelle , Lucas Céline , Blondeau Claude , Bardot Valérie , Ripoche Isabelle , Berthomier Lucile , Pallet Véronique , Layé Sophie , Joffre Corinne 
Published: October 2019

AbstractRhodiola rosea L. (R. rosea) is an adaptogenic plant increasing body resistance to stress. Its efficacy has been evidenced mainly in chronic stress models, data concerning its effect in acute stress and underlying mechanisms being scarce. The objective was to investigate the effect of repeated doses of a R. rosea hydroethanolic root extract (HRE) on hypothalamic pituitary adrenal response in a murine model of acute mild stress and also the mechanisms involved. Stress response was measured in Balb/c mice having received by gavage HRE (5 g/kg) or vehicle daily for 2 weeks before being submitted to an acute mild stress protocol (open‐field test then elevated plus maze). Corticosterone was measured in plasma from mandibular vein blood drawn before and 30, 60, and 90 min after initiation of the stress protocol. Mice were sacrificed at 90 min, and the hippocampus, prefrontal cortex, and amygdala were excised for high‐frequency RT‐PCR gene expression analysis. At 30 min after acute mild stress induction, corticosterone level in mice having received the HRE was lower than in control mice and comparable to that in nonstressed mice in the HRE group. HRE administration induced brain structure‐dependent changes in expression of several stress‐responsive genes implicated in neuronal structure, HPA axis activation, and circadian rhythm. In the acute mild stress model used, R. rosea HRE decreased corticosterone level and increased expression of stress‐responsive genes, especially in the hippocampus and prefrontal cortex. These findings suggest that R. rosea HRE could be of value for modulating reactivity to acute mild stress.
What do we know about individual equity options?
Authors: Bernales Alejandro , Verousis Thanos , Voukelatos Nikolaos , Zhang Mengyu 
Published: October 2019

AbstractThis paper examines the empirical literature on individual equity options, discussing results in areas of consensus, showing findings in areas of disagreement and providing a guide for future research (especially highlighting analyses that cannot be performed with index options). Key topics include the impact of equity option listings on the underlying stock market, option market efficiency, anomalies in equity option returns, option market microstructure, investors’ behavioral biases, option price discovery, and private information revealed in equity option markets. Some directions for future research include the determinants of equity option returns and the effect of algorithmic trading in option markets.
Reconstructed global monthly land air temperature dataset (1880–2017)
Authors: Wang Kang , Clow Gary D. 
Published: October 2019

AbstractLand surface air temperature is an essential climate variable for understanding rapid global environmental changes. Sparse network coverage prior to the 1950s is a significant source of uncertainty in global climate change evaluations. Recognizing the importance of spatial coverage, more stations are continually being added to global climate networks. A challenge is how to best use the information introduced by the new station observations to enhance our understanding and assessment of global climate states and changes, particularly for times prior to the mid‐20th century. In this study, Data INterpolating Empirical Orthogonal Functions (DINEOF) were used to reconstruct mean monthly air temperatures from the Global Historical Climatology Network‐monthly (GHCNm version 4) over the land surface from 1880 through 2017. The final reconstructed air temperature dataset covers about 95% of the global land surface area, improving the spatial coverage by ~80% during 1880–1900 and by 10%–20% since the 1950s. Validation tests show that the mean absolute error of the reconstructed data is less than 0.82°C. Comparison with the Coupled Model Intercomparison Project Phase 5 (CMIP5) climate model output shows that the reconstructed dataset substantially reduces the bias in global datasets caused by sparse station coverage, particularly before the 1950s.
Direct replication of task‐dependent neural activation patterns during sadness introspection in two independent adolescent samples
Authors: Vilgis Veronika , Rhoads Shawn A. , Weissman David G. , Gelardi Kristina L. , Forbes Erika E. , Hipwell Alison E. , Keenan Kate , Hastings Paul D. , Guyer Amanda E. 
Published: October 2019

AbstractFunctional neuroimaging results need to replicate to inform sound models of human social cognition and its neural correlates. Introspection, the capacity to reflect on one's thoughts and feelings, is one process required for normative social cognition and emotional functioning. Engaging in introspection draws on a network of brain regions including medial prefrontal cortex (mPFC), posterior cingulate cortex (PCC), middle temporal gyri (MTG), and temporoparietal junction (TPJ). Maturation of these regions during adolescence mirrors the behavioral advances seen in adolescent social cognition, but the neural correlates of introspection in adolescence need to replicate to confirm their generalizability and role as a possible mechanism. The current study investigated whether reflecting upon one's own feelings of sadness would activate and replicate similar brain regions in two independent samples of adolescents. Participants included 156 adolescents (50% female) from the California Families Project and 119 adolescent girls from the Pittsburgh Girls Study of Emotion. All participants completed the Emotion Regulation Questionnaire (ERQ) and underwent a functional magnetic resonance imaging scan while completing the same facial emotion‐processing task at age 16–17 years. Both samples showed similar whole‐brain activation patterns when engaged in sadness introspection and when judging a nonemotional facial feature. Whole‐brain activation was unrelated to ERQ scores in both samples. Neural responsivity to task manipulations replicated in regions recruited for socio‐emotional (mPFC, PCC, MTG, TPJ) and attention (dorsolateral PFC, precentral gyri, superior occipital gyrus, superior parietal lobule) processing. These findings demonstrate robust replication of neural engagement during sadness introspection in two independent adolescent samples.
Short‐Duration Pan‐Genotypic Therapy With Glecaprevir/Pibrentasvir for 6 Weeks Among People With Recent Hepatitis C Viral Infection
Authors: Martinello Marianne , Orkin Chloe , Cooke Graham , Bhagani Sanjay , Gane Edward , Kulasegaram Ranjababu , Shaw David , Tu Elise , Petoumenos Kathy , Marks Philippa , Grebely Jason , Dore Gregory J. , Nelson Mark , Matthews Gail V. 
Published: October 2019

Background and Aims
Among treatment‐naive individuals with chronic hepatitis C viral (HCV) infection and without cirrhosis, glecaprevir/pibrentasvir for 8 weeks is recommended. The aim of this analysis was to evaluate the efficacy of glecaprevir/pibrentasvir for 6 weeks in people with acute and recent HCV infection.

Approach and Results
In this open‐label, single‐arm, multicenter, international pilot study, adults with recent HCV (duration of infection < 12 months) received glecaprevir/pibrentasvir 300/120 mg daily for 6 weeks. Primary infection was defined by first positive anti‐HCV antibody and/or HCV RNA within 6 months of enrollment and either acute clinical hepatitis within the past 12 months (symptomatic seroconversion illness or alanine aminotransferase > 10 × upper limit of normal) or anti‐HCV antibody seroconversion within 18 months. Reinfection was defined as new positive HCV RNA within 6 months of enrollment and evidence of prior spontaneous or treatment‐induced clearance. The primary endpoint was sustained virologic response at 12 weeks posttreatment (SVR12). Thirty men (median age 43 years, 90% men who have sex with men) received treatment, of whom 77% (n = 23) were human immunodeficiency virus–positive, 47% (n = 14) had ever injected drugs, and 13% (n = 4) had HCV reinfection. The majority had HCV genotype 1 (83%, n = 25), followed by genotype 4 (10%, n = 3) and genotype 3 (7%, n = 2). At baseline, median estimated duration of infection was 29 weeks (range 13, 52) and median HCV RNA was 6.2 log10 IU/mL (range 0.9, 7.7). SVR12 in the intention‐to‐treat and per‐protocol populations was achieved in 90% (27/30) and 96% (27/28), respectively. There was one case of relapse, and there were two cases of nonvirological failure (death, n = 1; loss to follow‐up, n = 1). No treatment‐related serious adverse events were seen.

Conclusions
Glecaprevir/pibrentasvir for 6 weeks was highly effective among people with acute and recent HCV infection, supporting further evaluation of shortened‐duration pan‐genotypic therapy in this setting.
The relationships between work intensity, workaholism, burnout, and self‐reported musculoskeletal complaints
Authors: Engelbrecht Gerhard J. , de Beer Leon T. , Schaufeli Wilmar B. 
Published: October 2019

AbstractTechnological advances within the work environment have dynamically changed the tools with which work is done and the methods applied for performing it, with a large amount of modern work being fast‐paced and sedentary in nature, that is, being done seated in front of a computer screen. This study investigated the relationship between work intensity, workaholism, burnout, and musculoskeletal complaints (MSCs). The results of this study could assist organizations in gaining a clearer understanding of how each of these constructs influences the other, promoting a healthier, and ultimately more productive workforce. A cross‐sectional research design was adopted and implemented by means of a survey amongst office employees within a large engineering services organization (n = 398). Structural equation modeling methods were applied to analyze the data. The results revealed that work intensity was positively related to workaholism and that workaholism was, in turn, also positively related to employees’ burnout and MSCs. Finally, burnout was also shown to be significantly related to MSCs. Awareness of these phenomena and the promotion of effort recovery is important to obviate the effects on employee health and well‐being in the long term.