bluuebunny/crossref_metadata_2025_split huggingface dataset:
Green Total Factor Productivity and Its Nonlinear Relationship With Coordinated FDI Development: Evidence From Panel Models
Authors: Fan Lihong , Chang Bisharat Hussain , Kim Eunchan 
Published: December 2024

ABSTRACTThis study investigates the underexplored nonlinear impact of coordinated foreign direct investment on green total factor productivity in the context of China. While existing literature acknowledges the role of FDI in fostering economic growth and environmental development, it has yet to thoroughly address the synchronizing effects of inward and outward FDI on factor productivity, particularly in alignment with Sustainable Development Goals (SDGs) and ESG principles. Using provincial‐level data from 1995 to 2022 and employing a panel model, we analyze the U‐shaped relationship between FDI coordination on factor productively in the context of China. Our findings reveal that synchronized FDI significantly boosts GP in the economically advanced eastern provinces, whereas the effect is complex and region‐dependent in central and western areas, where structural and economic disparities play a more pronounced role. These results contribute to existing knowledge by clarifying the pathway through which coordinated FDI can enhance sustainable development. Our study concludes with policy recommendations emphasizing region‐specific strategies that balance economic growth and environmental goals, fostering a comprehensive approach to sustainable development.
Contagious risk: Nexus of risk in climate, epidemic, geopolitics, and economic
Authors: Li Hailing , Pei Xiaoyun , Zhang Hua 
Published: December 2024

AbstractIn recent years, “black swan” events have increasingly occurred across climate, epidemics, geopolitics, and economics, leading to a gradual coupling of different types of risk. Different from isolated shocks as a single type of risk affecting a specific industry, a nexus of risks allows one risk area to quickly relate to others, resulting in more catastrophic impacts. Utilizing an integrated framework, we investigate the contagion effects among climate policy uncertainty, the infectious disease equity market volatility tracker, geopolitical risk, and economic policy uncertainty using volatility, skewness, and kurtosis as risk measures. The results indicate that: (1) The contagion effect of different types of risk increases with higher order risk measures, suggesting that more extreme events are more likely to be contagious across domains. (2) Approximately two‐thirds of risk contagion occurs contemporaneously, while about one‐third occurs with a lag, indicating that risk contagion combines both immediacy and continuity. (3) Risk contagion exhibits significant time‐varying and heterogeneous characteristics. Our study elucidates the inherent contagion characteristics between different types of risk, transforming the understanding of risk from a one‐dimensional to a multidimensional perspective. This underscores that risk management should not be confined to a single domain; it is crucial to consider the potential impacts of risks from other industries on one's own.
Identification of the Novel HLA‐DPB1*01:01:15 Allele by Next‐Generation Sequencing
Authors: Oh Eun‐Sang , Chang Yunhee , DebRoy Meelie , Islam Humayun Kamal , Putheti Prabhakar 
Published: December 2024

ABSTRACTWe describe the novel HLA‐DPB1*01:01:15 allele found in a female African American.
The Novel HLA‐C*03:656 Allele Identified by Next‐Generation Sequencing
Authors: Shen Manli , Jennemann Jo‐Ellen , Willey Patricia , Liu Chang 
Published: December 2024

ABSTRACTHLA‐C*03:656 differs from HLA‐C*03:04:01:02 by a single missense nucleotide substitution in codon 342 in exon 7.
Characterisation of the Novel HLA‐G*01:06:01:02 Allele in a Tribal Individual From Western Maharashtra, India
Authors: Mujumdar Yogini , Thakur Shramika Vasant , Bhor Vikrant M. , Kulkarni Ragini Nitin , Chaaithanya Itta Krishna 
Published: December 2024

ABSTRACTHLA‐G*01:06:02:01 differs from HLA‐G*01:06:01:01 by one nucleotide substitution in intron 4 at position 1921 (C to T).
Three Fields Allelic Haplotype Frequencies of HLA‐DPA1 and ‐DPB1 Typed by Next Generation Sequencing of 563 Families in Chinese Han Population
Authors: Wang Jian‐Ling , He Jun‐Bo , Li Zhi‐Min , Zhu Ya‐Nan , Cao DaJiang , Fu Hong‐Lei , Zhang Xian , Fernández‐Viña Marcelo A. , Rozemuller Erik , Liu XiangJun 
Published: December 2024

ABSTRACTThe present study investigated the HLA‐DPA1 and ‐DPB1 allele and haplotype frequencies in the Chinese Han population. A total of 563 families, which have been typed for the purpose of haematopoietic stem cell transplantation, were included, and three‐field allelic resolution typing of HLA‐DPA1 and ‐DPB1 of all individuals were defined by the next‐generation sequencing method. HLA‐DPA1~DPB1 haplotypes were determined by allele segregation within a nuclear family. A total of 9 HLA‐DPA1 and 39 HLA‐DPB1 alleles, and 62 HLA‐DPA1~DPB1 haplotypes were identified. The three most frequent alleles at HLA‐DPA1 locus are HLA‐DPA1*02:02:02 (46.581%), HLA‐DPA1*01:03:01 (36.456%) and HLA‐DPA1*02:01:01 (12.167%); and the three most frequent HLA‐DPB1 alleles are HLA‐DPB1*05:01:01 (34.014%), HLA‐DPB1*02:01:02 (18.428%) and HLA‐DPB1*04:01:01 (10.124%). The three most frequent haplotypes are HLA‐DPA1*02:02:02~DPB1*05:01:01 (32.327%), HLA‐DPA1*01:03:01 ~ DPB1*02:01:02 (14.654%) and HLA‐DPA1*01:03:01~DPB1*04:01:01 (9.458%). The HLA‐DPA1*02:01~DPB1*02:02 and HLA‐DPA1*04:01~DPB1*05:01 haplotypes appear to be unique in Han Chinese. Strong global linkage disequilibrium (LD) between HLA‐DPA1 and ‐DPB1 was confirmed (D′ = 0.848, Wn = 0.684). Moreover, the haplotype frequencies based on the family study were compared with the frequencies estimated by the expectation–maximisation algorithm, and the equivalent results were obtained except for haplotypes with very low frequencies. Our data provide a solid base for HLA‐DP dimer association studies and useful information for transplantation and disease association studies.
Evaluating the Influence of Morphological Features on the Vulnerability of Lipid-Rich Plaques During Stenting
Authors: Colmenarez Jose A. , Dong Pengfei , Lee Juhwan , Wilson David L. , Gu Linxia 
Published: December 2024

Abstract
Lipid-rich atheromas are linked to plaque rupture in stented atherosclerotic arteries. While fibrous cap thickness is acknowledged as a critical indicator of vulnerability, it is likely that other morphological features also exert influence. However, detailed quantifications of their contributions and intertwined effects in stenting are lacking. Therefore, our goal is to assess the impact of plaque characteristics on the fibrous cap stress and elucidate their underlying mechanisms. We analyzed the stent deployment in a three-dimensional patient-specific coronary artery reconstructed from intravascular optical coherence tomography (IVOCT) data using the finite element method. Additionally, we performed sensitivity analysis on 78,000 distinct plaque geometries of two-dimensional arterial cross section for verification. Results from the three-dimensional patient-specific model indicate strong correlations between maximum fibrous cap stress and lipid arc (r=0.769), area stenosis (r=0.550), and lumen curvature (r=0.642). Plaques with lipid arcs &gt;60 deg, area stenosis &gt;75%, and lumen curvatures &gt;5 mm−1 are at rupture risk. While we observed a rise in stress with thicker lipid cores, it was less representative than other features. Fibrous cap thickness showed a poor correlation, with the sensitivity analysis revealing its significance only when high stretches are induced by other features, likely due to its J-shaped stress–stretch response. Contrary to physiological pressure, the stent expansion generates unique vulnerable features as the stent load-transferring characteristics modify the plaque's response. This study is expected to prompt further clinical investigations of other morphological features for predicting plaque rupture in stenting.
Supplemental Material: A 50 m.y. melting model for the rare metal–rich Koktokay pegmatite in the Chinese Altai: Implications from a newly identified Jurassic granite
Authors: Han Jinsheng , Chen Huayong , al. et 
Published: December 2024

<p>Table S1: Major-element (wt%) and trace-element (ppm) compositions of apatite from the granite apophysis and the Koktokay No. 3 pegmatite. Table S2: Major-element composition of columbite in the granite apophysis. Table S3: Major- and trace-element composition of micas in the granite apophysis. Table S4: Major (wt%) and trace (ppm) elements for the granite apophysis. Table S5: LA-ICP-MS U-Pb analytical results of columbites and apatites. Table S6: Whole-rock Sr-Nd-Hf isotopes of the granite apophysis in the Koktokay No. 3 pegmatite. Table S7: Multicollector LA-ICP-MS boron isotopes of tourmalines from the granite apophysis. Table S8: Compiled age data of magmatic-hydrothermal activity in the Koktokay No. 3 pegmatite. </p>
Inequalities in uptake of childhood vaccination in England, 2019-23: longitudinal study
Authors: Flatt Aidan , Vivancos Roberto , French Neil , Quinn Sophie , Ashton Matthew , Decraene Valérie , Hungerford Daniel , Taylor-Robinson David 
Published: December 2024

AbstractObjectiveTo quantify changes in inequalities in uptake of childhood vaccination during a period of steadily declining overall childhood vaccination rates in England.DesignLongitudinal study.SettingGeneral practice data for five vaccines administered to children (first and second doses of the measles, mumps, and rubella vaccine (MMR1 and MMR2, respectively), rotavirus vaccine, pneumococcal conjugate vaccine (PCV) booster, and six-in-one (DTaP/IPV/Hib/HepB) vaccine covering diphtheria, tetanus, pertussis, polio,Haemophilus influenzaetype b, and hepatitis B) from the Cover of Vaccination Uptake Evaluated Rapidly dataset in England.ParticipantsChildren aged <5 years eligible for vaccinations between April 2019 and March 2023 registered at primary care practices in England. 2 386 317 (2 309 674 for rotavirus vaccine) children included in the study were eligible at age 1 year, 2 456 020 at 2 years, and 2 689 304 at 5 years.Main outcome measuresChanges in quarterly vaccine uptake over time and compared by deprivation level. Regression analyses were used to quantify the change in inequalities in vaccine uptake over time—expressed as changes in the slope index of inequality (SII). Cumulative susceptibility to measles and rotavirus disease at age 5 years was estimated. Analyses were repeated at regional level.ResultsThe absolute inequality in vaccine uptake at baseline (2019-20) was largest for MMR2 in children at age 5 years (SII −9.6%, 95% confidence interval (CI) −10.2% to −9.0%). For all vaccinations studied, the SII for uptake increased over the study period: from −5.1% to −7.7% for the six-in-one vaccine, −7.4% to −10.2% for rotavirus, −7.9% to −9.7% for PCV booster, −8.0% to −10.0% for MMR1 at age 2 years, −3.1% to −5.6% for MMR1 at age 5 years, and −9.6% to −13.4% for MMR2 at age 5 years. The number of children susceptible to measles by the end of the study period increased 15-fold in the least deprived group (from 1364 to 20 958) and 20-fold in the most deprived group (from 1296 to 25 345). For rotavirus, a 14-fold increase was observed in the least deprived group (from 2292 to 32 981) and a 16-fold increase in the most deprived group (from 2815 to 45 201). Regional analysis showed greatest inequalities in uptake in London and the northern regions.ConclusionThe findings of this study suggest that inequalities in childhood vaccination are increasing in England, as uptake rates for five key childhood vaccinations decreased between 2019 and 2023, below the World Health Organization’s recommended 95% uptake target, and with noticeable regional differences. Urgent action is needed to strengthen systems for childhood vaccination, with a key focus on reducing inequalities.
Detection of Tick‐Borne Pathogen Coinfections and Coexposures to Foot‐and‐Mouth Disease, Brucellosis, and Q Fever in Selected Wildlife From Kruger National Park, South Africa, and Etosha National Park, Namibia
Authors: Cossu Carlo Andrea , Ochai Sunday Ochonu , Troskie Milana , Hartmann Axel , Godfroid Jacques , de Klerk Lin-Mari , Turner Wendy , Kamath Pauline , van Schalkwyk Ockert Louis , Cassini Rudi , Bhoora Raksha , van Heerden Henriette 
Published: December 2024

Background: Although the rate of emerging infectious diseases that originate in wildlife has been increasing globally in recent decades, there is currently a lack of epidemiological data from wild animals.Methodology: We used serology to determine prior exposure to foot‐and‐mouth disease virus (FMDV), Brucella spp., and Coxiella burnetii and used genetic testing to detect blood‐borne parasitic infections in the genera Ehrlichia, Anaplasma, Theileria, and Babesia from wildlife in two national parks, Kruger National Park (KNP), South Africa, and Etosha National Park (ENP), Namibia. Serum and whole blood samples were obtained from free‐roaming plains zebra (Equus quagga), greater kudu (Tragelaphus strepsiceros), impala (Aepyceros melampus), and blue wildebeest (Connochaetes taurinus). Risk factors (host species, sex, and sampling park) for infection with each pathogen were assessed, as well as the prevalence and distribution of co‐occurring infections.Results: In KNP 13/29 (45%; confidence interval [CI]: 26%–64%) kudus tested positive for FMD, but none of these reacted to SAT serotypes. For brucellosis, seropositive results were obtained for 3/29 (10%; CI: 2%–27%) kudu samples. Antibodies against C. burnetii were detected in 6/29 (21%; CI: 8%–40%) kudus, 14/21 (67%; CI: 43%–85%) impalas, and 18/39 (46%; CI: 30%–63%) zebras. A total of 28/28 kudus tested positive for Theileria spp. (100%; CI: 88%–100%) and 27/28 for Anaplasma/Ehrlichia spp. (96%; CI: 82%–100%), whereas 12/19 impalas (63%) and 2/39 zebra (5%) tested positive for Anaplasma centrale. In ENP, only 1/29 (3%; CI: 0%–18%) wildebeest samples tested positive for FMD. None of the samples tested positive for brucellosis, while C. burnetii antibodies were detected in 26/30 wildebeests (87%; CI: 69%–96%), 16/40 kudus (40%; CI: 25%–57%), and 26/26 plains zebras (100%; CI: 87%–100%). A total of 60% Anaplasma/Ehrlichia spp. and 35% Theileria/Babesia spp. in kudu and 37% wildebeest tested positive to Theileria sp. (sable), 30% to Babesia occultans, and 3%–7% to Anaplasma spp. The seroprevalence of Q fever was significantly higher in ENP, while Brucella spp., Anaplasma, Ehrlichia, Theileria, and Babesia species were significantly higher in KNP. Significant coinfections were also identified.Conclusion: This work provided baseline serological and molecular data on 40+ pathogens in four wildlife species from two national parks in southern Africa.
Política brasileira para a juventude: a proposta dos Centros da Juventude
Authors: Garcia Barreiro Rafael , Serrata Malfitano Ana Paula 
Published: December 2024

(descriptive): this study draws on the National Youth Policy of Brazil with the goal of understanding the role of Youth Centers (YCs) that are specifc places where young people can engage in culture and leisure activities. The method used in this study was in-depth interviews with YC managers in four Brazilian cities, as well as the State Manager and with National Manager of the program. The results showed differences in the discourse at each government level, evidencing a gap in their positions. The discourse from the federal and state levels highlighted the guarantee for young people to access their rights. In contrast, managers from the municipal level demonstrated that their political agenda is based on the provision of social assistance that targets poor young people while focusing their attention at the same time on the universality of rights. The authors conclude that the YCs have a limited connection with the National Youth Policy, demonstrating that the Brazilian government's actions need to improve the perception of young people as subjects of rights.

Key words: social policy, public administration, youth (Unesco Social Science Thesaurus).
Historical Moralism and the Law: Judicial Statements (panyu) in Late Imperial Civil Service Examinations
Authors: Qian Tony D. 
Published: December 2024

Abstract
From 1384 until 1757, the civil service examinations at the provincial and metropolitan levels included a test on “judicial statements” (panyu 判語)—hypothetical legal decisions written in response to five statutory titles selected mainly from the penal code. These decisions were composed in parallel prose of predominantly four- and six-character lines, and consisted of moral exhortations and historical allusions with little regard for the formal law. This article focuses on the panyu, not as a test of legal knowledge, but as a means of showcasing how principles of justice could be derived from a stock of received cultural and historical knowledge. In these texts, a cache of narratives, which were identified with specific statutes, imbued the law with a historical moralism that expounded on its provisions in non-technical terms. This article, by analyzing examples of panyu found in administrative manuals, annotated penal codes, and examination archives, shows how they sought to clarify the moral intent of the statutes, describe the moral basis for orthodox social values and order, and establish the moral standards for judging official (mis)conduct. Fundamentally, panyu served to strengthen the legitimacy of the law in the eyes of non-specialists and to provide a form of legal education for both officials and non-officials that was closely aligned with the classical training of the literati.
Henri van de Waal’s (1910-1972) unfinished Beeldleer: Exploring new potentials of an iconological classification for the history of the arts
Authors: Van Den Heuvel Charles 
Published: December 2024

Henri van de Waal (1910-1972), well-known for his development of Iconclass, also worked on a classification system of the arts that has remained unknown to many, entitled ‘Beeldleer’ (Iconology).This article explores the new potentials of Beeldleer, despite its unfinished and occasionally outdated character, to complement historical debates on iconology, and for future application in digital art history.
Firstly, it will be demonstrated, using unpublished archival documents of the development of Beeldleer, why it is a necessary addition to Iconclass to fully understand Van de Waals approaches of art history in general and his views on iconography and iconology in particular. Although Iconclass certainly has classes that are relevant beyond a history of art based purely on semantic meaning using foremost figurative examples, Beeldleer has additional value. A comparison between these classification systems revealed that the publication of Beeldleer, even in the unfinished state it has remained in, would allow for much completer descriptions of non-figurative aspects of the arts, also in non-Western contexts.
Secondly, Van de Waal’s contribution to iconology has merely been read through the lens of Iconclass and foremost in comparison with the views of Aby Warburg and Erwin Panofsky. Although Van de Waal admired these art historians, archival sources make clear that he put more emphasis on the role of observation to come to a theory of form. He regarded such a theory a precondition for iconology as a theory of meaning for understanding the function of the image in society. Van de Waal’s Beeldleer is not only relevant for the historiography of iconology in the Low Countries but can also contribute to analyses of international debates in the history of art and media studies (in particular around ‘Bildwissenschaft’). Moreover, after update of some classes, Beeldleer allows for classifying the outcomes of current analyses of the making of artworks and of global art history.
Thirdly, the article demonstrates that Beeldleer can be crucial in providing more art historical context in modeling and (pre-) classifying the outcomes of computer vision experiments. In particular, the many classes to capture formal aspects make Beeldleer very useful for such experiments in digital art history. The inclusion of many categories that refer to non-visual arts allows for linking to other classifications.
The publication of Beeldleer on the Semantic Web could be the realization of Van de Waal’s ‘globus iconographicus’, a tool designed to map uncharted areas of iconography and iconology.
EU Ecodesign and Product Policy: from Energy Efficiency to Circular Economy
Authors: Krämer Ludwig 
Published: December 2024

Abstract
Product policy plays a central role in the integration architecture of the European Union (EU). The need to protect the environment led in the beginning of the 21st century to a Commission initiative on an „Integrated Product Policy“. In 2005, it adopted a directive on the ecodesign of energy-using products. Hand in hand with this approach on the environmental performance of products, which aimed at influencing the making and marketing of products by professisonals, went the attempts to influence the consumer, by information on the product, in particular by energy labelling. This manuscript reviews the EU action in these two area’s and their linkage to circular economy, in light of their transparency and ability to achieve the envisaged goals.
Guideline concordance of aspirin use for primary prevention in adult outpatients
Authors: Chipalkatti Naina , Barnes Geoffrey D. , Bashaw Linda , Davie Adam , Griggs Jennifer J. , Harrod Molly , Kurlander Jacob E. , Medaugh Christine , Packard Rebeca , Powell Corey , Sood Suman , Spranger Elizabeth , Vordenberg Sarah E. , Schaefer Jordan K. 
Published: December 2024

Abstract
Recent guidelines have recommended a reduced role for primary prevention aspirin use, which is associated with an increased bleeding risk. This study aimed to characterize guideline-discordant aspirin use among adults in a community care setting. As part of a quality improvement initiative, patients at 1 internal medicine and 1 family medicine clinic affiliated with an academic hospital were sent an electronic survey. Patients were included if they were at least 40 years old, had a primary care provider at the specified site, and were seen in the last year. Patients were excluded if they had an indication for aspirin other than primary prevention. Responses were collected from 15 February to 16 March 2022. Analyses were performed to identify predictors of primary prevention aspirin use and predictors of guideline-discordant aspirin use; aspirin users and nonusers were compared using Fisher exact test, independent samples t tests, and multivariable logistic regression. Of the 1460 patients sent a survey, 668 (45.8%) responded. Of the respondents, 132 (24.1%) reported aspirin use that was confirmed to be for primary prevention. Overall, 46.2% to 58.3% of primary prevention aspirin users were potentially taking aspirin, contrary to the guideline recommendations. Predictors of discordant aspirin use included a history of diabetes mellitus and medication initiation by a primary care provider. In conclusion, primary prevention aspirin use may be overutilized and discordant with recent guideline recommendations for approximately half of the patients, suggesting a need for aspirin deimplementation. These efforts may be best focused at the primary care level.