bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decellularized Plant-Based Scaffolds for Guided Alignment of Myoblast Cells
Authors: Campuzano Santiago , Mogilever Nicolette B. , Pelling Andrew E. 
Published: February 2020

AbstractAlignment and orientation of cellsin vivoplays a crucial role in the functionality of tissue. A challenged faced by traditional cell culture approaches is that the majority of two-dimensional substrates fail to induce a controlled alignment of cellsin vitro. To address this challenge, approaches utilizing mechanical stresses, exposure to electrical fields, structurally aligned biomaterials and/or textured microfabricated substrates, have been developed to control the organization of cells through microenvironmental stimuli. In the field of muscle tissue engineering it is often desirable to control the alignment and fusion of muscle precursor cells as it more closely resemblesin vivoconditions. In this study, we utilize plant-derived cellulose biomaterials to control thein vitroalignment of C2C12 murine myoblasts. We hereby report that cells display a clear sensitivity to the highly aligned vascular bundle architectures found in decellularized celery (Apium graveolens). Conveniently, the xylem and phloem channels lie within the 10-100μm diameter, which has been shown to be optimal diameter for myoblast alignment through contact guidance. Following 10 days in proliferation media, F-actin filaments were observed to be aligned parallel to the longitudinal axis of the vascular bundle. Subsequently, following 5 days in differentiation media, myoblast maintained an aligned morphology, which led to the formation of aligned myotubes. We therefore conclude that the microtopography of the vascular bundle guides muscle cell alignment. The results presented here highlight the potential of this plant-derived scaffold forin vitrostudies of muscle myogenesis, where structural anisotropy is required to more closely resemblein vivoconditions.
Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex
Authors: Papagiannidis Dimitrios , Bircham Peter W. , Lüchtenborg Christian , Ruffini Giulia , Brügger Britta , Schuck Sebastian 
Published: February 2020

ABSTRACTCells dynamically adapt organelle size to current physiological demand. Organelle growth requires membrane biogenesis and therefore needs to be coordinated with lipid metabolism. The endoplasmic reticulum (ER) can undergo massive expansion, but the regulatory mechanisms that govern ER membrane biogenesis are largely unclear. Here, we conduct a genetic screen for factors involved in ER membrane expansion in budding yeast and identify the ER transmembrane protein Ice2 as a strong hit. We show that Ice2 promotes ER membrane biogenesis by opposing the phosphatidic acid phosphatase Pah1, which is called lipin in metazoa. Ice2 inhibits the conserved Nem1-Spo7 complex, which dephosphorylates and thus activates Pah1. Furthermore, Ice2 cooperates with the transcriptional regulation of lipid synthesis genes and helps to maintain ER homeostasis during ER stress. These findings establish inhibition of the lipin phosphatase complex as an important mechanism for controlling ER membrane biogenesis.
Compulsive buying of branded apparel, its antecedents, and the mediating role of brand attachment
Authors: Lim Xin-Jean , Cheah Jun-Hwa , Cham Tat Huei , Ting Hiram , Memon Mumtaz Ali 
Published: February 2020

PurposeCompulsive buying continues to be a maladaptive behavior that draws the attention of both scholars and marketers. The present study aims to investigate the determinants of compulsive buying, which are conceptualized as impulsive and obsessive–compulsive buying, and the mediation effect of brand attachment.Design/methodology/approachUsing purposive sampling, a self-administered questionnaire was completed by 600 young consumers in Malaysia. Partial least squares structural equation modeling was used to test the hypothesized relationships.FindingsThe results show that materialism, utilitarian value, and brand attachment are positively related to impulsive buying, while materialism, hedonic value, and brand attachment have a positive effect on obsessive–compulsive buying. In addition, brand attachment is found to mediate the effect of materialism and utilitarian value on both compulsive buying.Research limitations/implicationsThe study provides new insights into brand management literature by examining the predictors of impulsive and obsessive–compulsive buying. Moreover, brand attachment is found to be a significant mechanism that induces negative buying behavior. However, due to the growth of online shopping, future research should consider different types of retailers to provide a more comprehensive understanding of the subject matter in the modern business landscape.Originality/valueBeing one of the few studies to address both impulsive and obsessive–compulsive buying behaviors among consumers, this study highlights the essential role of brand attachment as a mediator in the contemporary setting. Moreover, the interrelationships between self-congruence, materialism, hedonic value, utilitarian value, brand attachment, and compulsive buying behavior are examined in a holistic manner.
DICOM-based medical image repository using DSpace
Authors: Hazarika Hirak Jyoti , Handique Akash , S. Ravikumar S. Ravikumar 
Published: February 2020

Purpose
This paper aims to provide image repository to the medical professional in an open source platform, which will increase the visibility of Digital Imaging and Communication in Medicine (DICOM) image in a network mode; further, the proposed system will reduce the storage cost of the images to significant level.

Design/methodology/approach
The authors have developed a new institutional repository model for the medical professionals cum radiologists to preserve, store and retrieve medical images from one database with the help of open source software. The authors used JavaScript programming to integrate and develop the DICOM Standard with DSpace.

Findings
Major outcome of this work is that DICOM images can be accommodated in DSpace without modifying the image properties and keeping intact the various dimensions of image viewing options. Further, it was found that the images are retrieved without any ease because of the robust indexing system.

Research limitations/implications
Major limitation of this study was the size of the data (5000 DICOM image) with which the authors have tested the system. The scalability of the system has to be tested on various fronts, for which separate study has to be done.

Practical implications
Once this system is in place, DICOM user can store, retrieve and access the image from Web platform. This proposed repository will be the storehouse of various DICOM images with reasonable storage costs.

Originality/value
In addition to exploring the opportunities of open source software (OSS) implementation in Medical Fields, this study includes issues related to implementation of open source repository for storing and preserving medical image. This is the first time in Library Science field to create and develop Open Source DICOM Medical Image Library with the help of DSpace. The study will create value for library professionals as well as medical professionals and OSS vendors to understand the medical market in the context of OSS.
Stay competitive in 2035: a scenario-based method to foresight in the design and manufacturing industry
Authors: Alizadeh Reza , Soltanisehat Leili 
Published: February 2020

Purpose
The purpose of this paper is to envision the alternative futures of the design and manufacturing industry using an integrated foresight method based on scenario planning. Also, the authors aim at developing robust strategies for an enterprise that aims to be placed as a leading high-tech international design and manufacturing company in 2035.

Design/methodology/approach
The proposed approach is created by integrating several foresight methods such as Delphi, scenario planning, MICMAC and cross-impact analysis.

Findings
Automation and sustainable development are found as the fundamental driving forces in the design and manufacturing industry. Four scenarios based on these driving forces and expert knowledge are created: innovation adaptation, forced automation (business-as-usual), sustainable era and automationless scenarios. For the developed scenarios, a set of strategies are proposed by asking experts about the strategies which can be taken to make the enterprise competitive in all developed scenarios in 2035. The main macro-level outcome is that economic and technological drivers will be the most important factors for design and manufacturing, followed by environmental and social factors.

Originality/value
The proposed method uses the strengths of traditional scenario planning but overcomes its weaknesses by suggesting a systematic process for scenario building and easy application.
Needs assessment for vocational skills training for unemployed youth in eThekwini Municipality, South Africa
Authors: Mayombe Celestin 
Published: February 2020

PurposeThe purpose of this paper is to examine how the eThekwini Municipal Academy (EMA) conducts training needs assessments for vocational skills training for unemployed and disadvantaged youths, KwaZulu-Natal province. By examining the process of training needs assessment (TNA), the focus was on determining how it might influence the success in employment outcomes of the graduates.Design/methodology/approachThe researcher used mixed research methods of qualitative and quantitative approaches. The quantitative research method was a survey questionnaire. The survey questionnaire helped produce a detailed description of respondents' opinions and experiences. The qualitative method in the form of semi-structured interviews helped to present the data from the perspective of the training managers on the process of TNA and opportunities in accessing employment for the graduates. Purposive sampling was used to select 24 training centre managers and 512 trainees. The quantitative data were analysed using SPSS software, and data from interviews were analysed using thematic analysis.FindingsThe findings revealed that the most important aspect of the TNA process was that the EMA managers selected and design a training course after consulting and engaging the stakeholders who were also prospective employers to identify needs and job availability within the companies or government departments. The author concludes that the process of TNA involving all stakeholders helped to provide vocational training programmes, which were demand-driven. The process also might promote the best and most promising practices enhancing the transition from skills acquisition to skills utilisation in the labour market.Practical implicationsThe results of the study have shown the three main factors that affect the TNA process, which are an individual or person analysis, consulting key stakeholders and labour market assessment. It is hoped that the results of the study can be used by training practitioners for better understanding of factors that can contribute to the effectiveness of vocational skills training for unemployed youth.Originality/valueThe paper is unique because it contributes to the knowledge by explaining the link between the effectiveness of vocational skills training and a proper TNA for unemployed youth. It also provides knowledge on key factors in conducting the TNA process by involving all stakeholders. Existing TNA research focuses on competency-based need analysis for employees of companies, organisations and institutions. Therefore, this paper is significant because it helps to understand the role of TNA in enhancing the effectiveness of vocational skills training for unemployed and disadvantaged youths.
What make banks’ front-line staff more customer oriented? The role of interactional justice
Authors: Dang Thuy T. , Pham Anh D. 
Published: February 2020

PurposeWhile technological advances have been changing the way that services are delivered to customers, direct interaction between banks’ front-line staff and customers still holds its distinct position in the banking sector. This research investigates the relationship between interactional justice and the willingness of commercial banks’ front-line staff to engage in customer-centric behaviors, as well as the mediators behind this relationship.Design/methodology/approachThis research combined both qualitative and quantitative research methods. In-depth interviews were employed to explore the potential mechanisms underlying the relationship between interactional justice and customer-centric behavior and to develop the specific measurement scale for customer-centric behavior in the banking service context. A survey was conducted to test the conceptual model using a sample of 312 customer contact employees working in Vietnamese commercial banks.FindingsThe research results indicate that interactional justice significantly enhances employees’ willingness to engage in customer-centric behaviors, and this relationship is partially mediated by overall job satisfaction and the leader-member exchange relationship.Research limitations/implicationsThis research faces several limitations. The first limitation concerns the fact that the data are based on self-reports, which might lead to common method biases. Second, this study used a sample drawn from the North of Vietnam only. Third, this study adopted a limited set of measurement items due to the concerns of model parsimony and data collection efficiency. Fourth, we followed prior justice work to assume the linear relationship between interactional justice and leader-member exchange, in which the leader-member exchange is hypothesized to be the outcome of fair treatment (Erdogan and Liden, 2006; Mastersonet al., 2000). Last, we only considered how leaders treat their followers through the lens of interactional justice, while interactional justice differentiation has also been affirmed as a crucial determinant of leader-member exchange and employees’ performance.Originality/valueThis research is noteworthy that it is the first to take a social exchange perspective to examine customer-oriented behavior as an outcome of interpersonal interactions in the workplace. Accordingly, it delivers a key message to bank supervisors: “Treat employees the way you want your customers to be treated.”
Research on the influence of balance patch on players' character preference
Authors: Wang Qi , Yang Yi , Li Zhengren , Liu Na , Zhang Xiaohang 
Published: February 2020

PurposeThe balance patch is an important but not well studied area to maintain game fairness and improve player entertainment. In this paper, we examine the effect of balance patch on player's character preference and further explore the moderating effect of psychological distance and character selection pattern.Design/methodology/approachIn study 1, a web crawler was used to get server-side data of 40, 974 multi-player online battle arena (MOBA) players through official application programming interfaces (APIs). A paired-Ttest and a stepwise regression were performed to verify the hypothesis. In study 2, a 2-patch type (buff vs nerf) × 2 psychological distance (near vs distant) × 2 character selection pattern (stable vs variable) between-subjects design was adopted to confirm the empirical conclusions through questionnaire survey design and further explored the mediating effect of patch adjustment perception.FindingsThe analyzed results showed that the buff patch led to an increase in players' character preference, while the nerf patch led to a decrease in players' character preference. Moreover, the main effect was mediated by patch adjustment perception. Furthermore, psychological distance and character selection pattern both moderated the relationship between balance patch and character preference changes. The character preference of the near psychological distance increased more significantly elicited by buff patches and decreased more significantly in an adverse situation. Similarly, players with variable selection pattern of characters were more sensitive to the stimuli, and the character preference of the variable group changed more significantly than that of the stable group caused by balance patch release.Originality/valueThis paper studies the influence of a patch on the balance of character strength on player preference, which expands the research on game balance and fairness. The present results contribute to the theoretical research on consumer behavior of psychological distance and character selection pattern elicited by balance patches. Meanwhile, the results indicate that psychological distance theory can apply to the study of the relationship between players and virtual characters.
Dynamic factor demand in the Japanese manufacturing industry
Authors: Kim Sangho 
Published: February 2020

PurposeThis study investigates the dynamic production structure of the Japanese manufacturing industry by using the adjustment cost approach. The study is to shed some light on the unique dynamic structure of the Japanese manufacturing industry. The study attempts to help design and predict industrial policies that are implemented to enhance domestic investments by the Japanese government.Design/methodology/approachThis study obtains a system of dynamic factor demand and output supply equations by applying the dual approach to the intertemporal value function as represented by the Hamilton–Jacobi equation. By using industrial panel data for 1973–2012 of the Japanese manufacturing industry, the study estimates the system of the behavioral equations and corresponding elasticities. The study uses hypothesis tests and dynamic elasticities to investigate the dynamic structure of the Japanese manufacturing industry.FindingsEstimation results show that labor and capital are quasi-fixed variables that adjust about 0.2 percent annually to the long-run optimum levels. Estimated adjustment rates are very slow as often presumed about the Japanese manufacturing industry, which uses lifetime employment practice and slow decision-making process in investment decisions. The results also show that output supply and factor demand elasticities vary greatly depending on time horizon. Factor demand increases when its own price increases in the short run, suggesting that factor adjustment is mostly determined factor prices in the past due to sluggish factor adjustment. However, factor demand becomes a normal downward-sloping curve in the long run as factor adjustment gets completed.Originality/valueJapanese manufacturing firms hire employees through lifetime contract to exploit the benefits of dynamic learning-by-doing and execute investments carefully considering all the possible impacts. Under the strategy, adjustment costs for changing workers and capital stock are minimized. Dynamic adjustment model is expected to shed some light on the unique dynamic structure of the Japanese manufacturing industry. However, researches regarding the dynamic factor adjustment of the Japanese manufacturing industry are hard to find. This study is expected to fill the research vacuum.
Hedging and effectiveness of Indian currency futures market
Authors: Kharbanda Varuna , Singh Archana 
Published: February 2020

Purpose
The purpose of this paper is to measure the effectiveness of the hedging with futures currency contracts. Measuring the effectiveness of hedging has become mandatory for Indian companies as the new Indian accounting standards, Ind-AS, specify that the effectiveness of hedges taken by the companies should be evaluated using quantitative methods but leaves it to the company to choose a method of evaluation.

Design/methodology/approach
The paper compares three models for evaluating the effectiveness of hedge – ordinary least square (OLS), vector error correction model (VECM) and dynamic conditional correlation multivariate GARCH (DCC-MGARCH) model. The OLS and VECM are the static models, whereas DCC-MGARCH is a dynamic model.

Findings
The overall results of the study show that dynamic model (DCC-MGARCH) is a better model for calculating the hedge effectiveness as it outperforms OLS and VECM models.

Practical implications
The new Indian accounting standards (Ind-AS) mandates the calculation of hedge effectiveness. The results of this study are useful for the treasurers in identifying appropriate method for evaluation of hedge effectiveness. Similarly, policymakers and auditors are benefitted as the study provides clarity on different methods of evaluation of hedging effectiveness.

Originality/value
Many previous studies have evaluated the efficiency of the Indian currency futures market, but with rising importance of hedging in the Indian companies, Reserve Bank of India’s initiatives and encouragement for the use of futures for hedging the currency risk and now the mandatory accounting requirement for measuring hedging effectiveness, it has become more relevant to evaluate the effectiveness of hedge. To the authors’ best knowledge, this is one of the first few papers which evaluate the effectiveness of the currency future hedging.
Forms of suicide communication are not associated with five-factor personality
Authors: Schuler Kaitlyn R. , Basu Natasha , Fadoir Nicholas A. , Marie Laura , Smith Phillip N. 
Published: February 2020

PurposeUS age-adjusted suicide rates increased by 33 per cent from 1999 to 2017 (Hedegardet al., 2018). Communications about suicide and death are a commonly cited warning sign (SPRC, 2014) and are foundational to the vast majority of risk assessment, prevention and intervention practices. Suicidal communications are critically understudied despite their implications for prevention and intervention practices. The purpose of this study is to examine the association between five factor model personality traits and forms of suicidal communications.Design/methodology/approachA sample of 154 people admitted to emergency psychiatry for suicide ideation or attempt completed self-report measures about their suicide ideation and behavior. Kruskal–Wallis ANOVA examined differences between five-factor model personality domains and forms of communications.FindingsThere were no significant differences; however, two nonsignificant trends related to indirect or non-communication and extraversion and openness emerged.Research limitations/implicationsFuture studies should focus on using more nuanced measures of dimensional personality and suicidal communications.Originality/valueThis study is the first to examine differences in the Five-Factor Model personality traits and suicidal communications.