bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stress-Cultural Democracy Da'wah at the Mosque
Authors: Syarifudin Syarifudin , Ren Baiti , Fitri Fitri 
Published: August 2020

This study examines the collision of democratic systems through the election of village heads and the process of the resilience of cultural da'wah at mosques, which has an impact on the weakening of dakwah in Kampung Baru and Lonthor Banda Neira villages. The issue of the discussion examines the da'wah experience of mosque administrators regarding the encounter of democracy through the process of cultural da'wah at the mosque. This research uses a case study method with a qualitative approach. Data collection techniques through observation, interviews, and focus discussion groups. This study's results indicate that the adaptation of a democratic culture through village head elections occurs cultural stress between mosque administrators who maintain the resilience of the dakwah culture with a democratic system through the voting of the village head in Banda Neira. The cultural stress process goes through three stages: the cultural meeting stage, cultural clash action, cultural assimilation, and artistic collaboration. Due to social stress, social reality creates a feeling of shame, underappreciation, and a weakening of the solidarity of mosque administrators. Penelitian ini mengkaji benturan sistem demokrasi melalui pemilihan kepala desa dan proses ketahanan dakwah kultural pada masjid, yang berdampak terhadap pelemahan dakwah di desa Kampung baru dan Lonthor Banda Neira. Isu pembahasannya mengkaji pengalaman dakwah pengurus masjid terhadap perjumpaan demokrasi melalui proses dakwah kultural di Masjid. Penelitian ini menggunakan metode studi kasus dengan pendekatan kualitatif. Teknik pengumpulan data melalui observasi, wawancara, dan focus discussion group. Hasil penelitian ini menunjukkan bahwa adabtasi budaya demokrasi melalui pemilihan kepala desa terjadi stress cultural antara pengurus masjid yang menjaga ketahanan cultural dakwah dengan sistem demokrasi melalui pemilihan kepala Desa di Banda Neira. Proses stress cultural melalui tiga tahap yakni; tahap meeting cultural, aksi benturan cultural, cultural asimilation, dan collaboration cultural. Realitas sosial akibat stress cultural memunculkan rasa malu, kurang dihargai, dan melemahnya solodaritas pengurus masjid.
Hak Pendapatan Pekerja Perempuan dalam Al-Qur’an
Authors: Noorchasanah N. 
Published: August 2020

The Qur'an teaches about balance relationship between men and women in the scope of social life. In reality, there are a lot of scholars and interpretator have the point of view that women should limit themselves to be active in the public area’s. So there are the issues related to the protection of the income rights of women workers themselves. Wahbah Zuhaili and Quraish Shihab itself was a figure of nowadays interpretator who often discuss gender equality. The model used in this interpretation is a descriptive analysis, which revealed the interpretation Wahbah Zuhaili and Quraish Shihab is based on the issues related to interpretation books Al-Misbah and Al-Munir. The thematic interpretation methods used in assessing the verses associated with it, particularly on gender. Wahbah Zuhaili and Quraish Shihab explain that women have equal status with men because women have their own rights. so it is fitting female workers have the same rights as male workers, both in terms of income, protection, opportunities of employment and gain comfort within the scope of its work. And this was in accordance with the rules possessed by Islam itself, where men and women both are equal and equally rewarded in accordance with what has been cultivated by the individual. Wahbah Zuhaili and Quraish Shihab also prohibit discrimination on the matter. So that the results of the analysis are expected to be implemented in the making of policies relating to the income rights of women workers themselves.
Teaching and Learning English as a Second Language in Nigeria: Examining Evolving Approaches and Methods
Authors: Adebileje Adebola , Akinola Aderonke 
Published: August 2020

This paper examines language teaching and learning theories in a bid to consider evolving and appropriate approaches and methods for efficient teaching and learning English as a second language in Nigeria. While traditional approaches do provide a solid foundation for effective language teaching, they do not always address students' situational and current needs. Hence, the study reveals that strategies and methods are evolving especially, in this hi-tech age, to meet such additional needs. Since no one theory or method is the best, the study recommends a principled eclectic approach for the effective and functional teaching and learning of English in Nigeria. It also suggests processes that could enhance teaching and motivate learning in the ESL classroom.
A Cognitive Study of Double-object Constructions in English and Chinese
Authors: Li Yuanmei 
Published: August 2020

Double-object is a kind of syntactic structure which is common in English and Chinese. In the field of linguistics in China, the similarities and differences between English and Chinese double-object sentences have been discussed and debated. Based on the perspective of cognitive linguistics, this paper probes into the metaphor cognition, metonymy cognition and both of them in the double-object constructions of English and Chinese, and points out that the double-object constructions in English and Chinese are similar in the above three aspects. However, there are also differences between English and Chinese double-object constructions, which are manifested in the following three aspects: the scope of double-object constructions, the conceptual patterns and the verbs that can enter the double-object constructions. By analyzing the similarities and differences between English and Chinese double-object constructions, it can be concluded that the syntactic structure of English and Chinese objects reflects the conceptual structures of human beings and the ways of cognition of the world, and even the sentence structure containing the same conceptual content will lead to the difference in meaning because of the different cognitive styles of events.
Subasta de vidas y humanitarismo estratégico: la Unión Europea y la crisis de refugiados desde una óptica crítica
Authors: Ghotme-Ghotme Rafat Ahmed 
Published: August 2020

Este artículo tiene como propósito analizar las consecuencias de la crisis de refugiados que experimentó la Unión Europea en el 2015. A través de un marco teórico denominado «realismo crítico», se pudo establecer que la crisis de refugiados en Europa no fue abordada con base en los principios humanitarios que inspiran los fundamentos de la Unión, sino más bien a través de diversas medidas soberanistas que tienen como fin poner freno a la entrada de más refugiados; la crisis también puso en evidencia la relativa fragilidad institucional de esa institución, reflejada en su incapacidad para crear un sistema centralizado dirigido a distribuir proporcionalmente la población refugiada a lo largo de Europa. Sin embargo, la Unión Europea sí cumplió con una función básica: a través de diversas medidas sustentadas en los intereses individuales de “seguridad”, detuvo la entrada y de hecho rechazó a centenares de miles de refugiados que esperaban entrar a Europa. El presente trabajo sostendrá que esas medidas son producto de cierto atavismo identitario (racista), así como una estrategia de diversos actores que instrumentalizaron la crisis para avanzar en sus agendas políticas.
Sistematik Review: Dampak Perkuliahan Daring Saat Pandemi COVID-19 Terhadap Mahasiswa Indonesia
Authors: Argaheni Niken Bayu 
Published: August 2020

<p><strong>Background</strong>: Learning online and working from home for educators is a change that must be made by lecturers to continue teaching students. Distance education has the aim of improving the quality of education and the relevance of education as well as increasing the equitable access and expansion of education. Distance Education that is carried out with good quality assurance and in accordance with the needs of stakeholders is one mechanism for expanding access to quality higher education that is expected.</p><p><strong>Method</strong>: Systematic review using a database: Google Scholar. Search results that fulfill the criteria are then analyzed by article.</p><p><strong>Results</strong>: Online learning has several impacts on students, namely (1) Online Learning Still Confuses Students (2) Students become passive, less creative and productive, (3) The accumulation of information / concepts on students is less useful, (4) Students Experiencing Stress, (5) Improvement of Student Language Literacy Ability.</p><p><strong>Conclusion</strong>: At present, the spread of Covid-19 still shows an upward trend so that education practitioners and stakeholders can continue to survive and innovate in implementing learning. This is because good learning is able to invite students' interest and attention.</p><p> </p>
Hubungan Pola Diet Remaja dengan Status Gizi
Authors: Yunita Fresthy Astrika , Hardiningsih Hardiningsih , Yuneta Agus Eka Nurma , Sulaeman Endang Sutisna , Ada' Yeremia Rante 
Published: August 2020

<p><strong>Latar Belakang</strong> : Pada usia remaja pelajar lebih mementingkan penampilan fisik. Remaja putri termasuk kelompok yang rentan mengalami masalah gizi. Remaja yang masih dalam tahap pertumbuhan terobsesi ingin memiliki penampilan fisik yang menarik dengan melakukan cara yang salah diantaranya melakukan diet ketat, latihan keras dan asupan makan yang buruk sehingga hal ini menjadi penyebab umum masalah gizi pada remaja dan dapat mempengaruhi proses tumbuh kembang.</p><p><strong>Tujuan penelitian</strong>:Untuk mengetahui pola diet remaja, mengetahui status gizi remaja dan untuk menganalisis hubungan pola diet remaja dengan status gizi.</p><p><strong>Subjek dan </strong><strong>Metode penelitian</strong>: Jenis penelitian analitik observasional dengan desain penelitian <em>cross sectional </em>yaitu<em> </em>untuk mengetahui hubungan pola diet remaja dengan status gizi. Penelitian dilakukan di SMP 18 Surakarta. Populasi yang digunakan dalam penelitian ini adalah remaja putri di SMP 18 Surakarta .Teknik pencuplikan sampel menggunakan <em>simple random sampling, </em>jumlah sampel sebanyak 30 remaja putri. Alat ukur dalam penelitian ini adalah kuesioner dan lembar observasi. Analisis data dilakukan dengan uji statistik <em>Kolmogorov-spirnov</em><em>.</em></p><p><strong>Hasil P</strong><strong>enelitian :</strong> Mayoritas remaja putri di SMP 18 Surakarta melakukan diet yaitu sebesar 60% (16 responden), serta mayoritas remaja putri di SMP 18 Surakarta mengalami status gizi kurus yaitu sebesar 50% (15 responden). Dari hasil uji statistik uji <em>kolmogorov-spirnov</em> diperoleh nilai p = 0.023 yang berarti terdapat hubungan pola diet remaja dengan status gizi.</p><p><strong>Kesimpulan</strong> : Terdapat hubungan antara pola diet remaja dengan status gizi</p><p> </p>
A contribuição do food miles na logística de transporte do mamão: do campo ao entreposto
Authors: Bigaran Aliotte Joseane Thereza , Mendonça Lima Dag , Ramos de Oliveira Andréa Leda 
Published: August 2020

Destaques: O mamão é uma das frutas mais consumidas pela população brasileira. Por ser uma fruta de alta perecibilidade sua logística depende de uma gestão eficiente. Nesse sentido, o conceito food miles busca garantir a qualidade do alimento e a redução das perdas e desperdícios, através da adoção de uma cadeia logística de distribuição e de comercialização mais eficiente, percorrendo menores distâncias entre a produção e o consumo.Objetivo: Avaliar se a distância percorrida ao longo do transporte do mamão para comercialização interfere nas perdas e desperdícios. Desenhos/Metodologia/Abordagem: Aplicação do conceito food miles de forma quantitativa através do método Weighted Average Source Distance (WASD) para promover estratégias logísticas mais eficientes para produtos perecíveis.Resultados: A maior parte das rotas do mamão se enquadram na categoria rotas longa e média-longa. O principal resultado encontrado foi uma distância média de food miles de 1.359 km a partir de diversos municípios produtores e diferentes níveis de volume de produção. Este valor é classificado como uma rota de distância média-longa.Limitações da investigação: Avaliação detalhada das práticas operacionais durante o transporte.Implicações práticas: As longas distâncias percorridas entre a origem e destino somados aos impactos causados durante o transporte podem contribuir para um aumento dos índices de perdas e desperdícios. Isto porque durante o transporte o mamão é acondicionado em embalagens inadequadas e em caminhões não refrigerados não garantindo a preservação da fruta. Além disto, as longas distâncias implicam não só em aumento do custo de transporte, mas também numa maior emissão de CO2.Originalidade/valor: O uso do conceito de food miles de forma aplicada e quantitativa permite aos tomadores de decisão pensar em uma logística mais ajustada, de modo a buscar rotas mais sustentáveis e eficientes, não só em termos de custo mas também em rotas que impactem menos o meio ambiente.
Drug Repurposing in Oncology: Current Evidence and Future Direction
Authors: Zhang Zhenzhan , Ji Jianguang , Liu Hao 
Published: August 2020

Background:
Drug repurposing, the application of known drugs and compounds
with a primary non-oncology purpose, might be an attractive strategy to offer more effective
treatment options to cancer patients at a low cost and reduced time.

Methods:
This review described a total of 10 kinds of non-oncological drugs from more than
100 mechanical studies as well as evidence from population-based studies. The future direction
of repurposed drug screening is discussed by using patient-derived tumor organoids.

Results:
Many old drugs showed previously unknown effects or off-target effects and can be
intelligently applied for cancer chemoprevention and therapy. The identification of repurposed
drugs needs to combine evidence from mechanical studies and population-based studies.
Due to the heterogeneity of cancer, patient-derived tumor organoids can be used to screen
the non-oncological drugs in vitro.

Conclusion:
These identified old drugs could be repurposed in oncology and might be added
as adjuvants and finally benefit patients with cancers.
Screening and Identification of Differentially Expressed Genes Between Diabetic Nephropathy Glomerular and Normal Glomerular via Bioinformatics Technology
Authors: Du Junjie , Yang Jihong , Meng Lingbing 
Published: August 2020

Background:
Diabetes is a chronic metabolic disease characterized by disorders of glucose
and lipid metabolism. Its most serious microvascular complication is diabetic nephropathy (DN),
which is characterized by varying degrees of proteinuria and progressive glomerulosclerosis,
eventually progressing to end-stage renal failure.

Objective:
The aim of this research is to identify hub genes that might serve as genetic markers to
enhance the diagnosis, treatment, and prognosis of DN.

Methods:
The procedures of the study include access to public data, identification of differentially
expressed genes (DEGs) by GEO2R, and functional annotation of DEGs using enrichment analysis.
Subsequently, the construction of the protein-protein interaction (PPI) network and identification
of significant modules were performed. Finally, the hub genes were identified and analyzed, including
clustering analysis, Pearson’s correlation coefficient analysis, and multivariable linear regression
analysis.

Results:
Between the GSE30122 and GSE1009 datasets, a total of 142 DEGs were identified,
which were mainly enriched in cell migration, platelet activation, glomerulus development,
glomerular basement membrane development, focal adhesion, regulation of actin cytoskeleton, and
the PI3K-AKT signaling pathway. The PPI network was composed of 205 edges and 142 nodes. A
total of 10 hub genes (VEGFA, NPHS1, WT1, PODXL, TJP1, FYN, SULF1, ITGA3, COL4A3,
and FGF1) were identified from the PPI network.

Conclusion:
The DEGs between DN and control glomeruli samples may be involved in the occurrence
and development of DN. It was speculated that hub genes might be important inhibitory
genes in the pathogenesis of diabetic nephropathy, therefore, they are expected to become the new
gene targets for the treatment of DN.
Design, Synthesis and Biological Evaluation of 3-(2-(benzo[d]thiazol-2- ylthio)acetamido)benzoic Acid Derivatives as Inhibitors of Protein Tyrosine Phosphatase 1B
Authors: Rakse Monika , Karthikeyan Chandrabose , Narayana Moorthy Narayana Subbiah Hari , Agrawal Ram Kishore 
Published: August 2020

Background:
Protein Tyrosine Phosphatase 1B (PTP1B) is an attractive target for antidiabetic
drug discovery owing to its pivotal role as a negative regulator of insulin and leptin signaling.

Objective:
The objective of this research is to design, synthesize, and evaluate some acetamidobenzoic
acid derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors with therapeutic
potential for Type II diabetes.

Methods:
3-(2-(Benzo[d]thiazol-2-ylthio)acetamido)benzoic acid derivatives 4(a-j) were synthesized
and characterized by employing spectral studies. All the synthesized compounds were
screened for in vitro PTP1B inhibitory activity and the most potent compound in the series was also
evaluated for in vivo anti-hyperglycemic activity using STZ induced diabetic Wistar rat model. Molecular
docking studies were also performed with the most potent analog using FlexX docking algorithm
to delineate its binding mode to the active site of the PTP1B.

Results:
Among all the synthesized compounds, 3-(2-(benzo[d]thiazol-2-ylthio)acetamido)-4-
methylbenzoic acid (4f) displayed good PTP1B inhibitory activity with an IC50 value of 11.17 μM.
The compound also exhibited good anti hyperglycemic efficacy in streptozotocin induced diabetic
Wistar rats. Docking studies with 4f revealed that the compound bound in the catalytic and second
aryl binding site of the PTP1B.

Conclusion:
Overall, compound 4f with good in vitro PTP1B inhibitory potency and in vivo antihyperglycemic
efficacy would be a valuable lead molecule for the development of acetamidobenzoic
acid based PTP1B inhibitors with antidiabetic potential.
App-Based Delivery of Clinical Emotional Freedom Techniques: Cross-Sectional Study of App User Self-Ratings
Authors: Church Dawson , Stapleton Peta , Sabot Debbie 
Published: August 2020

BackgroundThe burgeoning area of mobile health (mHealth) has experienced rapid growth in mobile apps designed to address mental health issues. Although abundant apps offer strategies for managing symptoms of anxiety and stress, information regarding their efficacy is scarce.ObjectiveThis study aimed to assess the effect of an mHealth app on user self-ratings of psychological distress in a sample of 270,461 app users. The Tapping Solution App guides users through the therapeutic protocols of Clinical Emotional Freedom Techniques (EFT), an evidence-based psychophysiological intervention that combines acupressure with elements of cognitive and exposure therapies.MethodsApp users provided self-ratings of emotional intensity before and after app sessions (termed “tapping meditations”) using an 11-point Subjective Units of Distress scale. App user data for 23 tapping meditations, which addressed psychological symptoms of anxiety and stress, were gathered between October 2018 and October 2019, totaling 380,034 completed app sessions.ResultsAcross 12 anxiety-tapping meditations, the difference in emotional intensity ratings from presession (mean 6.66, SD 0.25) to postsession (mean 3.75, SD 0.30) was statistically significant (P<.001; 95% CI −2.92 to −2.91). Across 11 stress-tapping meditations, a statistically significant difference was also found from presession (mean 6.91, SD 0.48) to postsession (mean 3.83, SD 0.54; P<.001; 95% CI −3.08 to −3.07). The results are consistent with the literature on the efficacy of Clinical EFT for anxiety and stress when offered in conventional therapeutic formats.ConclusionsThe findings provide preliminary support for the effectiveness of the mHealth app in the immediate reduction of self-rated psychological distress. As an adjunct to professional mental health care, the app promises accessible and convenient therapeutic benefits.
Strategic urban planning of religious cities: the case study of Karbala city in Iraq
Authors: Al-Daini Raeda , Samaneh Asadi , Danilina Nina V. 
Published: August 2020

Introduction. The issue of choosing the strategic development vector becomes key to the sustainability of cities that have great cultural and historical significance and serve as religious centres. The religious factor produces a high effect on all urban processes and has to be considered whenever urban development is planned. This issue is particularly relevant for Iraqi cities, as they have suffered greatly over the past years.
Materials and methods. The article offers an urban planning approach to assessing the current situation in the urban environment in order to determine the strategic vector of the city’s future development. We used the SWOT analysis method that allowed us to apply a systematic approach to assessing the strengths and weaknesses that determine the current situation, and to identify development opportunities and threats that may act as hurdles. The SWOT analysis is applied to transportation planning in Karbala, Iraq.
Results. Principal theoretical and experimental results, relevant data, relationships and regularities, identified in the course of the research, are presented in the article. At the same time, new results and data of lasting significance, important discoveries, conclusions that overturn existing theories, as well as the data that, in the co-authors’ opinion, are of practical importance are preferred.
Conclusions. The data, obtained by the co-authors, should serve as the basis for a strategic plan of urban development of Karbala city, Iraq. Also, the approach and method of urban research, used there, can be applied to other religious cities that face similar problems affecting their sustainability and the quality of their urban environment.