bluuebunny/crossref_metadata_2025_split huggingface dataset:
Review on pesticide residue on rice
Authors: Asiah N , David W , Ardiansyah  , Madonna S 
Published: November 2019

Abstract
Pesticide residue in rice has been investigated since the growing of demand of food safe. The determination of pesticide residues in food is becomes an essential requirement for consumers, producers and authorities responsible for food quality control. This study is aiming to show the information regarding agrochemical residue in rice from meta-analysis. This study showed that there are three major of agrochemical has been use as Pesticide, Fungicide, Herbicide and Insecticide. Effect of processing (milling) may decrease the pesticide contamination. Pesticide residue is adverse effect on human health problems.
The development potential of goat for poverty reduction in Windusari Subdistrict, Magelang Regency
Authors: Utomo S , Rasminati N 
Published: November 2019

Abstract
This research was conducted in two villages with poor category, Wonoroto and Ngemplak villages, Windusari subdistrict of Magelang regency, aiming to know the potential of local resources for the development of goats, in order to eradicate poverty. Primary data were taken by census of 35 goat farmers in the two villages, while competitor’s livestock data were sampled on 50 sheep breeder. Cattle competitors’ data were calculated based on monograph data of two research villages. The data analysis was done descriptively on the production of forage (in dry matter), goats population on adult, young and kid phase. Based on the results of the research, it was known that every household of goat farmers had production of feed sources (dry matter) for ruminant livestock as much as 1954.87 kg. Thus, the capacities of livestock per household were 0.85 animal unit equivalent to 6 adult goats or 1 head of heifers. It was found that the average land that produced fodder for two villages was 350.77 ha. The production of forage (DM) in Ngemplak and Wonoroto villages in one year averaged 363.05 ton/year or total of two villages was 726.10 ton/year, then the two areas had the capacity of livestock as much as 315.69 AU or about 157.85 AU for each village. The performance of goat reproductive in two areas, the average sex ratio was 1: 6.5, with the first kidding of 18 months, the kidding interval of 8.9 months and littersize 1.3. It is concluded that each goat-raiser family is still possible to increase its ownership, the area of two poor villages is still able to accommodate goats as much as 8,275 AU, with reproduction status which still needs to improve again.
The performance of beef cattle with feed based on the rice straw fermentation
Authors: Sukaryani S , Mulyono A M W 
Published: November 2019

Abstract
The research was conducted in a cow pen belonging to the Anhini Lestari Livestock group in Karanganyar Regency. The purpose of this research are 1) to examine the effect of giving fermented rice straw in rations to the performance of beef cattle; 2) to assess how much fermented rice straw can replace the elephant grass. The design was used a completely andomized design in one way pattern as 3 types of treatments and each treatment was repeated for 4 times. This research used 12 heads of PO cattle, about 2 years old cow, which were treated with the formula ration as follows: T0: 60% concentrate + 40% elephant grass; T1: 60% concentrate + 20% elephant grass + 20% fermented rice straw; T2: 60% concentrate + 20% the elephant grass + 20% the rice straw without fractionation. Variables that is observed including the consumption of dry matter, consumption of crude protein and daily weight gain. The obtained data were analyzed using variance analysis with a level of 1% and 5%, if there were differences between treatments Duncan’s New Multiple Range Test was carried out. The results of this research showed that the utilization of fermented rice straw in the ration had a very significant effect on the performance of PO beef cattle. The best treatment in improving the performance of PO cattle was in T1 treatment, namely PBBH of 440 g/head/day; BK consumption is 21075 gr/head/day; PK consumption of 2264,529 gr/head/day. It can be concluded that fermented rice straw using a combination of Aspergillus niger and Trichoderma mutants AA1 can replace elephant grass by 20%.
Metal-insulator-metal plasmonic grating filter with suppressed Rayleigh anomaly
Authors: Shakya Jyotindra R , Wang Alan X 
Published: November 2019

Abstract
Plasmonic grating filters can be fabricated in single lithography process and reduce the cost of colour filters used in hyperspectral cameras. Due to the presence of Rayleigh Anomaly (RA) peak, however, it has not been possible to design filter array spanning wide-spectral-range without sacrificing spectral purity. In this paper, a plasmonic grating filter design using Metal-Insulator-Metal (MIM) with suppressed RA peak is presented. Proposed filter allows extending spectral range without sacrificing spectral purity. Using proposed MIM structure, surface plasmon polariton (SPP) mode supported on air side of bottom grating structure is cancelled by second set of SPP mode on top grating structure. This allows designing filter array with improved spectral range and achieves better than 2× improvement in suppression of the Rayleigh Anomaly peak.
Sound and Silence in Peter Jackson’s They Shall Not Grow Old
Authors: Meyer Jessica 
Published: November 2019

Abstract
This roundtable offers four diverse perspectives on Peter Jackson’s innovative and controversial World War I documentary film They Shall Not Grow Old (2018). Jackson’s film breaks the mold of the documentary genre in its manipulation and montage of the visual and audio archives held at the Imperial War Museum in London. Yet he puts his technical virtuosity and resources at the service of a very traditional interpretation of the war, focusing almost entirely on the experience of young Englishmen on the Western Front. Scholars Santanu Das, Susan R. Grayzel, Jessica Meyer, and Catherine Robson offer their reflections on both the gains and losses of Jackson’s paradoxical original use of historical documents and old-fashioned rendering of the war’s experiential elements. They consider, respectively, the experience of colonial troops, the place of women in the war, and Jackson’s creative, if controversial, interpretation of the visual and aural archive.
Development of health-system inpatient pharmacy clinical metrics
Authors: Cassat Stacy , Massey Lindsay , Buckingham Stephanie , Kemplay Tamara , Little Jeff 
Published: November 2019

Abstract

Purpose
To describe a process to identify metrics that represent the impact of inpatient pharmacy services on patient outcomes across a health system.

Summary
The authors describe a systematic process of identifying inpatient clinical outcome measures that could represent pharmacists’ impact on patient outcomes and eventually be displayed in a dashboard within the electronic medical record (EMR). A list was generated through literature review, assessment of practices at other sites, evaluation of current pharmacy services, and collaboration with the quality department and System Pharmacy Clinical User Group. The project team narrowed the list through assessment against standardized criteria. An assessment tool was designed and distributed to stakeholders to prioritize clinical outcome measures for inclusion on the dashboard. The clinical outcome measures were transformed into metrics by determining measurement criteria, inclusion and exclusion parameters, and review time frame. After validation, the metrics are planned to be displayed on an inpatient pharmacy EMR dashboard. Exemption from institutional review board review was granted for this project.

Conclusion
A systematic process was developed and used to identify inpatient clinical outcome metrics.
On higher-order logical grounds
Authors: Fritz Peter 
Published: November 2019

AbstractExistential claims are widely held to be grounded in their true instances. However, this principle is shown to be problematic by arguments due to Kit Fine. Stephan Krämer has given an especially simple form of such an argument using propositional quantifiers. This note shows that even if a schematic principle of existential grounds for propositional quantifiers has to be restricted, this does not immediately apply to a corresponding non-schematic principle in higher-order logic.
xpression of aquaporin subtypes (GhPIP1;1, GhTIP2;1, and GhSIP1;3) in cotton (Gossypium hirsutum L.) submitted to salt stress
Authors: Braz Luana C C , Fernandes Pedro D , Barbosa Daniela D , Dutra Wellison F , Silva Carliane R C , Lima Liziane M , Cavalcanti José J V , Farias Francisco J C , Santos Roseane C 
Published: November 2019

Abstract
Salinization leads to several worldwide damages in agricultural regions, mainly in semiarid regions where leaching of salt is poor due to limited and erratic rainfall. Cotton (Gossypium hirsutum L.) is a Malvaceae with wide genetic variability to salt stress. The identification of salinity tolerant genotypes is a dynamic target in a breeding program, and the selection is often based on plant phenotypes. Molecular markers are reliable tools to aid in these selection procedures. Aquaporin (AQPs) are channel proteins that play fundamental role in water relations and tolerance to environmental stresses. Plants have fine regulation of water transport through AQPs activities. In order to evaluate the AQP expressions of different cotton cultivars submitted to salt stress, we use molecular and physiological tools, based on RT-qPCR and gas exchange assays. Seven cultivars were submitted to 95 mM NaCl, started at V3 stage (21 days after emergence), during 72 h. At the end of stress treatment, root tissues were used to total RNA extraction, followed by cDNA synthesis and RT-qPCR analyzes. Three sets of specific primers were used, drawn from AQP accessions deposited in NCBI. Additionally, full expanded leaves were used to gas exchange assays and to estimate the relative water content. The dry matter of the shoots was also evaluated. Based on pattern of AQPs transcripts, we found that all semiarid tolerant cultivars (BRS Seridó, 7MH, CNPA MT 2009 152 and BRS 416) showed downregulation of AQP subtypes, mainly GhPIP1;1 and GhTIP2;1 whose action is characterized as tolerant to salinity. The results of gas exchanges, relative water content and dry matter were consistent with the molecular findings in these cultivars, confirming that GhPIP1;1 and GhTIP2;1, located at plasma membrane and vacuoles, respectively, could be adopted as AQP markers for identification of cotton tolerant to salt stress.
DTI-CDF: a cascade deep forest model towards the prediction of drug-target interactions based on hybrid features
Authors: Chu Yanyi , Kaushik Aman Chandra , Wang Xiangeng , Wang Wei , Zhang Yufang , Shan Xiaoqi , Salahub Dennis Russell , Xiong Yi , Wei Dong-Qing 
Published: November 2019

Abstract
Drug–target interactions (DTIs) play a crucial role in target-based drug discovery and development. Computational prediction of DTIs can effectively complement experimental wet-lab techniques for the identification of DTIs, which are typically time- and resource-consuming. However, the performances of the current DTI prediction approaches suffer from a problem of low precision and high false-positive rate. In this study, we aim to develop a novel DTI prediction method for improving the prediction performance based on a cascade deep forest (CDF) model, named DTI-CDF, with multiple similarity-based features between drugs and the similarity-based features between target proteins extracted from the heterogeneous graph, which contains known DTIs. In the experiments, we built five replicates of 10-fold cross-validation under three different experimental settings of data sets, namely, corresponding DTI values of certain drugs (SD), targets (ST), or drug-target pairs (SP) in the training sets are missed but existed in the test sets. The experimental results demonstrate that our proposed approach DTI-CDF achieves a significantly higher performance than that of the traditional ensemble learning-based methods such as random forest and XGBoost, deep neural network, and the state-of-the-art methods such as DDR. Furthermore, there are 1352 newly predicted DTIs which are proved to be correct by KEGG and DrugBank databases. The data sets and source code are freely available at https://github.com//a96123155/DTI-CDF.
Sexual dimorphism in Belostoma angustum Lauck (Insecta: Heteroptera: Belostomatidae) may be related to paternal care
Authors: Lopes Cassiane Furlan , Stefanello Fabiano , Bugs Christian , Stenert Cristina , Maltchik Leonardo , Ribeiro José Ricardo Inacio 
Published: November 2019

AbstractThe structures involved in parental care are often dimorphic. Female Belostoma angustum water bugs lay eggs on the hemelytra of their mates, where the eggs are brooded until hatching. Males use their hind legs to carry, aerate and protect the eggs. After controlling for covariance between variables, we fitted a series of structural equation models (SEMs) and evaluated the existence of sexual dimorphism in the size of the body and hind legs, in the shape and centroid size of the hemelytrum, and among the static allometry slopes of the size-related differences. Landmarks were used to capture phenotypic variation, by eliminating all non-shape variations with a Procrustes superimposition. Neither the shape of the hemelytrum nor its centroid size was related significantly to the aforementioned linear body measurements. Instead, the differences in the size of the hind legs were mediated by body dimensions only in males. We also found that males were wider and had longer heads than females, according to the SEM intercept values. Our findings suggest that sexual dimorphism in B. angustum may be related to a balance between sexual role reversal and viability costs.
Knowledge Exchange and Social Capital for Freshwater Ecosystem Assessments
Authors: Kuehne Lauren M , Strecker Angela L , Olden Julian D 
Published: November 2019

Abstract
The 1972 Clean Water Act (CWA) provided crucial environmental protections, spurring research and corresponding development of a network of expertise that represents critical human capital in freshwater conservation. We used social network analysis to evaluate collaboration across organizational types and ecosystem focus by examining connections between authors of freshwater assessments published since the CWA. We found that the freshwater assessment network is highly fragmented, with no trend toward centralization. Persistent cohesion around organizational subgroups and minimal bridging ties suggest the network is better positioned for diversification and innovation than for learning and building a strong history of linked expertise. Despite an abundance of research activity from university-affiliated authors, federal agency authors provide a majority of the bonding and bridging capital, and diverse agencies constitute the core network. Together, our results suggest that government agencies currently play a central role in sustaining the network of expertise in freshwater assessment, protection, and conservation.
Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms
Authors: Miao Qing-Long , Herlitze Stefan , Mark Melanie D , Noebels Jeffrey L 
Published: November 2019

Abstract
Inborn errors of CACNA1A-encoded P/Q-type calcium channels impair synaptic transmission, producing early and lifelong neurological deficits, including childhood absence epilepsy, ataxia and dystonia. Whether these impairments owe their pathologies to defective channel function during the critical period for thalamic network stabilization in immature brain remains unclear. Here we show that mice with tamoxifen-induced adult-onset ablation of P/Q channel alpha subunit (iKOp/q) display identical patterns of dysfunction, replicating the inborn loss-of-function phenotypes and, therefore demonstrate that these neurological defects do not rely upon developmental abnormality. Unexpectedly, unlike the inborn model, the adult-onset pattern of excitability changes believed to be pathogenic within the thalamic network is non-canonical. Specifically, adult ablation of P/Q channels does not promote Cacna1g-mediated burst firing or T-type calcium current (IT) in the thalamocortical relay neurons; however, burst firing in thalamocortical relay neurons remains essential as iKOp/q mice generated on a Cacna1g deleted background show substantially diminished seizure generation. Moreover, in thalamic reticular nucleus neurons, burst firing is impaired accompanied by attenuated IT. Interestingly, inborn deletion of thalamic reticular nucleus-enriched, human childhood absence epilepsy-linked gene Cacna1h in iKOp/q mice reduces thalamic reticular nucleus burst firing and promotes rather than reduces seizure, indicating an epileptogenic role for loss-of-function Cacna1h gene variants reported in human childhood absence epilepsy cases. Together, our results demonstrate that P/Q channels remain critical for maintaining normal thalamocortical oscillations and motor control in the adult brain, and suggest that the developmental plasticity of membrane currents regulating pathological rhythmicity is both degenerate and age-dependent.
Re-Enchanting Nature and Medicine
Authors: Ridenour Autumn Alcott 
Published: November 2019

AbstractResponding to Max Weber’s modern diagnosis of nature, science, and medicine as disenchanted, this article aims to reenvision nature and medicine with a sense of enchantment drawing from the Christian themes of creation, Christology, suffering, and redemption. By reenvisioning nature as enchanted with these theological themes, the vocation of medicine might be revitalized in terms of suffering presence, healing care, and works of mercy toward the neighbor in need.
Seasonal Influenza Vaccine Effectiveness in People With Asthma: A National Test-Negative Design Case-Control Study
Authors: Vasileiou Eleftheria , Sheikh Aziz , Butler Chris C , Robertson Chris , Kavanagh Kimberley , Englishby Tanya , Lone Nazir I , von Wissmann Beatrix , McMenamin Jim , Ritchie Lewis D , Schwarze Jürgen , Gunson Rory , Simpson Colin R 
Published: November 2019

AbstractBackgroundInfluenza infection is a trigger of asthma attacks. Influenza vaccination can potentially reduce the incidence of influenza in people with asthma, but uptake remains persistently low, partially reflecting concerns about vaccine effectiveness (VE).MethodsWe conducted a test-negative designed case-control study to estimate the effectiveness of influenza vaccine in people with asthma in Scotland over 6 seasons (2010/2011 to 2015/2016). We used individual patient–level data from 223 practices, which yielded 1 830 772 patient-years of data that were linked with virological (n = 5910 swabs) data.ResultsVaccination was associated with an overall 55.0% (95% confidence interval [CI], 45.8–62.7) risk reduction of laboratory-confirmed influenza infections in people with asthma over 6 seasons. There were substantial variations in VE between seasons, influenza strains, and age groups. The highest VE (76.1%; 95% CI, 55.6–87.1) was found in the 2010/2011 season, when the A(H1N1) strain dominated and there was a good antigenic vaccine match. High protection was observed against the A(H1N1) (eg, 2010/2011; 70.7%; 95% CI, 32.5–87.3) and B strains (eg, 2010/2011; 83.2%; 95% CI, 44.3–94.9), but there was lower protection for the A(H3N2) strain (eg, 2014/2015; 26.4%; 95% CI, −12.0 to 51.6). The highest VE against all viral strains was observed in adults aged 18–54 years (57.0%; 95% CI, 42.3–68.0).ConclusionsInfluenza vaccination gave meaningful protection against laboratory-confirmed influenza in people with asthma across all seasons. Strategies to boost influenza vaccine uptake have the potential to substantially reduce influenza-triggered asthma attacks.
Machine Learning to Identify Persons at High-Risk of Human Immunodeficiency Virus Acquisition in Rural Kenya and Uganda
Authors: Balzer Laura B , Havlir Diane V , Kamya Moses R , Chamie Gabriel , Charlebois Edwin D , Clark Tamara D , Koss Catherine A , Kwarisiima Dalsone , Ayieko James , Sang Norton , Kabami Jane , Atukunda Mucunguzi , Jain Vivek , Camlin Carol S , Cohen Craig R , Bukusi Elizabeth A , Van Der Laan Mark , Petersen Maya L 
Published: November 2019

Abstract

Background
In generalized epidemic settings, strategies are needed to prioritize individuals at higher risk of human immunodeficiency virus (HIV) acquisition for prevention services. We used population-level HIV testing data from rural Kenya and Uganda to construct HIV risk scores and assessed their ability to identify seroconversions.

Methods
During 2013–2017, &gt;75% of residents in 16 communities in the SEARCH study were tested annually for HIV. In this population, we evaluated 3 strategies for using demographic factors to predict the 1-year risk of HIV seroconversion: membership in ≥1 known “risk group” (eg, having a spouse living with HIV), a “model-based” risk score constructed with logistic regression, and a “machine learning” risk score constructed with the Super Learner algorithm. We hypothesized machine learning would identify high-risk individuals more efficiently (fewer persons targeted for a fixed sensitivity) and with higher sensitivity (for a fixed number targeted) than either other approach.

Results
A total of 75 558 persons contributed 166 723 person-years of follow-up; 519 seroconverted. Machine learning improved efficiency. To achieve a fixed sensitivity of 50%, the risk-group strategy targeted 42% of the population, the model-based strategy targeted 27%, and machine learning targeted 18%. Machine learning also improved sensitivity. With an upper limit of 45% targeted, the risk-group strategy correctly classified 58% of seroconversions, the model-based strategy 68%, and machine learning 78%.

Conclusions
Machine learning improved classification of individuals at risk of HIV acquisition compared with a model-based approach or reliance on known risk groups and could inform targeting of prevention strategies in generalized epidemic settings.

Clinical Trials Registration
NCT01864603.