bluuebunny/crossref_metadata_2025_split huggingface dataset:
All-Solid-State Asymmetric Supercapacitor Based on Ni–Co Layered Double Hydroxide and rGO Nanocomposite Deposited on Ni Foam
Authors: Lokhande P. E. , Chavan U. S. 
Published: January 2020

Abstract
In recent years, supercapacitors have been extensively exploited as an alternative energy storage technology in various fields such as electronics, computer, and mechanical. In this context, we have reported the utilization of the Ni–Co LDH/rGO nanostructure, deposited on the 3D conductive nickel substrate, to fabricate electrode for supercapacitor application. The film formed on the nickel substrate demonstrated superior electric conductivity and higher surface area which resulted in rapid electron transfer and more active mass deposition. Vertical nanorods grown on the rGO sheet was found to maximize electrode performance with a maximum specific capacitance of 2987 Fg−1at a current density of 1 Ag−1. The asymmetric supercapacitor was fabricated with Ni–Co LDH/rGO as a positive electrode and rGO as a negative electrode, which has rendered an energy density of 39.9 Wh/kg with a power density of 1.48 kW/kg1. Based on the obtained results, the fabricated supercapacitor is envisioned to be exploited in various potential applications.
Statistical Performance Analysis and Robust Design of Paper Microfluidic Membraneless Fuel Cell With Pencil Graphite Electrodes
Authors: Rao Lanka Tata , Dubey Satish Kumar , Javed Arshad , Goel Sanket 
Published: January 2020

Abstract
Paper-based membraneless microfluidic fuel cell (PMMFC) has emerged as an alternative to conventional fuel cells. Extraction of optimum energy yield from these PMMFCs requires selection and study of various design and operating parameters. In this context, this paper presents reliability analysis and robust design of PMMFC composed of air-breathing graphite electrodes using multiple concentrations of formic acid and sulfuric acid as fuel and electrolyte, respectively. Combinations of four different grades of pencils are employed to prepare the electrodes using various pencil strokes. PMMFC is analyzed for two different orientations—horizontal and vertical, and the maximum power outputs were recorded. In order to analyze the combined effects of different factors governing the performance of PMMFC, a statistical approach of full factorial design is utilized to perform analysis of mean (ANOM), analysis of variance (ANOVA), signal to noise ratio (SNR), and desirability study. The response equations in terms of coded values of the factors are also derived. Rigorous desirability study, with the optimized parameters, concludes that the best desirability values for the horizontal and vertical arrangements of PMMFC are 0.8842 and 0.92768, respectively. Overall, this study helps to develop reliable, robust, and efficient PMMFC for many realistic applications.
Compliance With 24-Hour Movement Guidelines in Hong Kong Adolescents: Associations With Weight Status
Authors: Shi Yan , Huang Wendy Yajun , Sit Cindy Hui-Ping , Wong Stephen Heung-Sang 
Published: January 2020

Background: This study examined the compliance with the 24-Hour Movement Guidelines among Hong Kong adolescents and its associations with body mass index (BMI). Methods: A total of 1039 adolescents (11–18 y) wore the activPAL™ for 24 hours for 7 consecutive days to assess physical activity (PA) and sleep duration. Screen time was measured using the Children’s Leisure Activities Study Survey (Chinese version). Linear mixed models were performed for analysis. Results: The analytic sample consisted of 692 adolescents (53% girls). Only 1.0% of the adolescents met all of the recommendations. The proportions of adolescents who met the recommendation for PA, screen time, and sleep were 9.1%, 31.2%, and 38.6%, respectively. Adolescent boys who did not meet the PA recommendation (β = 3.36; 95% CI, 1.04 to 5.68; P = .001) and those who did not meet the combination of PA and sleep recommendations (β = 2.10, 95% CI, 0.64 to 3.56; P = .01) had a higher body mass index than those who met the respective recommendations. Conclusions: Compliance with the 24-Hour Movement Guidelines was alarmingly low among Hong Kong adolescents. Meeting the PA recommendation or the combination of PA and sleep recommendations was associated with a healthier body weight in boys.
Middle and late Pleistocene pluvial history of Newark Valley, central Nevada, USA
Authors: Redwine Joanna R. , Burke R.M. , Reheis M.C. , Bowers R.J. , Bright J. , Kaufman D.S. , Forester* R.M. 
Published: January 2020

ABSTRACT
Newark Valley lies between the two largest pluvial lake systems in the Great Basin, Lake Lahontan and Lake Bonneville. Soils and geomorphology, stratigraphic interpretations, radiocarbon ages, and amino acid racemization geochronology analyses were employed to interpret the relative and numerical ages of lacustrine deposits in the valley. The marine oxygen isotope stage (MIS) 2 beach barriers are characterized by well-preserved morphology and deposits with youthful soil development, with Bwk horizons and maximum stage I+ carbonate morphology. Radiocarbon ages of gastropods and tufas within these MIS 2–age deposits permit construction of a latest Pleistocene lake-level curve for Newark Valley, including a maximum limiting age of 13,780 ± 50 14C yr B.P. for the most recent highstand, and they provide a calibration point for soil development in lacustrine deposits in the central Great Basin. The MIS 8–age to MIS 4–age beach barriers are higher in elevation and represent a larger lake than existed during MIS 2. The beach barriers have subdued morphology, are only preserved in short segments, and have stronger soil development, with Bkm and/or Bkmt horizons and maximum stage III+ to IV carbonate morphology. Newark Lake reached elevations higher than the MIS 2 highstand during at least two additional pluvial periods, MIS 16 and MIS 12, 10, or 8. These oldest lacustrine deposits do not have preserved shoreline features and are represented only by gravel lags, buried deposits, and buried soils with similar strong soil development. This sequence of middle and latest Pleistocene shorelines records a long-term pluvial history in this basin that remained internally drained for the last four or more pluvial cycles.
Obtaining numerical ages from material within lacustrine deposits in the Great Basin can be challenging. Amino acid D/L values from gastropod shells and mollusk valves proved to be a valuable tool to correlate lacustrine deposits within Newark Valley. Comparison of soils and geomorphology results to independent 36Cl cosmogenic nuclide ages from a different study indicated unexpected changes in rates of soil development during the past ~200,000 yr and suggested that common stratigraphic changes in lake stratigraphy could obscure incremental changes in soil development and/or complicate 36Cl cosmogenic nuclide age estimates.
A new stratigraphic framework and constraints for the position of the Paleocene–Eocene boundary in the rapidly subsiding Hanna Basin, Wyoming
Authors: Dechesne Marieke , Currano Ellen D. , Dunn Regan E. , Higgins Pennilyn , Hartman Joseph H. , Chamberlain Kevin R. , Holm-Denoma Christopher S. 
Published: January 2020

AbstractThe Paleocene–Eocene strata of the rapidly subsiding Hanna Basin give insights in sedimentation patterns and regional paleogeography during the Laramide orogeny and across the climatic event at the Paleocene–Eocene Thermal Maximum (PETM). Abundant coalbeds and carbonaceous shales of the fluvial, paludal, and lacustrine strata of the Hanna Formation offer a different depositional setting than PETM sections described in the nearby Piceance and Bighorn Basins, and the uniquely high sediment accumulation rates give an expanded and near-complete record across this interval. Stratigraphic sections were measured for an ∼1250 m interval spanning the Paleocene–Eocene boundary across the northeastern syncline of the basin, documenting depositional changes between axial fluvial sandstones, basin margin, paludal, floodplain, and lacustrine deposits. Leaf macrofossils, palynology, mollusks, δ13C isotopes of bulk organic matter, and zircon sample locations were integrated within the stratigraphic framework and refined the position of the PETM. As observed in other basins of the same age, an interval of coarse, amalgamated sandstones occurs as a response to the PETM. Although this pulse of relatively coarser sediment appears related to climate change at the PETM, it must be noted that several very similar sandstone bodies occur with the Hanna Formation. These sandstones occur in regular intervals and have an apparent cyclic pattern; however, age control is not sufficient yet to address the origin of the cyclicity. Signs of increased ponding and lake expansion upward in the section appear to be a response to basin isolation by emerging Laramide uplifts.
Retinal vessel diameter changes after 6 months of treatment in the Idiopathic Intracranial Hypertension Treatment Trial
Authors: Moss Heather E , Hollar Rachel A , Fischer William S , Feldon Steven E 
Published: January 2020

Background/AimsPrior studies support an association between increased retinal venule diameter and elevated intracranial pressure (ICP). The purpose of this study was to test the hypothesis that retinal venule diameters decrease in association with long-term therapy for high ICP in subjects with idiopathic intracranial hypertension (IIH).MethodsThis is a retrospective analysis of multicentre randomised controlled trial data. Standardised procedures were used to measure area of optic nerve head elevation (ONHA) and diameters of 4 arterioles and 4 venules 2.7 mm from the optic disc centre on fundus photos collected at baseline and after 6 months of randomised treatment with placebo+diet or acetazolamide+diet in subjects participating in the IIH Treatment Trial (IIHTT) (n=115). Change in arteriole (Da) and venule (Dv) diameters from baseline to 6 months was studied as a function of IIH, haemodynamic and demographic variables.ResultsDv decreased following 6 months of therapy (8.1 µm, 5.9%, p<0.0005) but Da did not change. Dv change was associated with ONHA change (p<0.0005, r=0.47) and this association persisted in multiple variable models.ConclusionsRetinal venule diameter decreased, and arteriole diameter did not change in association with treatment for elevated ICP with a weight loss intervention and placebo or acetazolamide in IIHTT participants. Further study is needed to determine how retinal vessel measurements can be combined with other clinical observations to inform disease management.
Conjunctival lymphangiectasia as a biomarker of severe systemic disease in Ser77Tyr hereditary transthyretin amyloidosis
Authors: Bunod Roxane , Adams David , Cauquil Cécile , Francou Bruno , Labeyrie Céline , Bourenane Halima , Adam Clovis , Algalarrondo Vincent , Slama Michel , Darce-Bello Martha , Barreau Emmanuel , Labetoulle Marc , Rousseau Antoine 
Published: January 2020

AimsTo investigate the relationship between the ophthalmic and systemic phenotypes in patients with hereditary transthyretin amyloidosis with the S77Y mutation (ATTRS77Y).MethodsIn this cross-sectional study, patients with genetically confirmed ATTRS77Y amyloidosis were enrolled. All patients underwent complete neurological examination, including staging with the Neuropathy Impairment Score (NIS), Polyneuropathy Disability (PND) score; complete cardiological evaluation, including echocardiography, cardiac MRI and/or cardiac scintigraphy and complete ophthalmic evaluation, including slit lamp examination and fundus examination. Ocular ancillary tests (fluorescein and indocyanine green angiography, and anterior segment optical coherence tomography) were performed in cases with abnormal findings. The Kruskal-Wallis test was used for quantitative outcomes and Fisher’s exact test for qualitative outcomes. Statistical significance was indicated by p<0.05 (two tailed).ResultsThe study sample was composed of 24 ATTRS77Y patients. The mean patient age was 58.4±12.4 years. None of the patients presented with amyloid deposits in the anterior chamber, secondary glaucoma or vitreous amyloidosis. Retinal angiopathy was observed in four patients, complicated with retinal ischaemia in one patient. Conjunctival lymphangiectasia (CL) was detected in 13 patients (54%), associated with perilymphatic amyloid deposits. The presence of CL was statistically associated with more severe neurological disease (NIS=43.3±31.9 vs 18.9±20.4; PND=2.6±1.0 vs 1.4±0.7 in patients with and without CL, respectively; both p<0.05) and amyloid cardiomyopathy (p=0.002).ConclusionIn ATTRS77Y patients, CL is common and could serve as a potential biomarker for severe systemic disease. There were neither anterior chamber deposits, secondary glaucoma nor vitreous deposits in ATTRS77Y patients.
The effect of eHealth-based falls prevention programmes on balance in people aged 65 years and over living in the community: protocol for a systematic review of randomised controlled trials
Authors: Ambrens Meghan , Tiedemann Anne , Delbaere Kim , Alley Stephanie , Vandelanotte Corneel 
Published: January 2020

IntroductionBetween 20% and 28% of community-dwelling older people experience a fall each year. Falls can result in significant personal and socioeconomic costs, and are the leading cause of admission to hospital for an older person in Australia. Exercise interventions that target balance are the most effective for preventing falls in community-dwellers; however, greater accessibility of effective programmes is needed. As technology has become more accessible, its use as a tool for supporting and promoting health and well-being of individuals has been explored. Little is known about the effectiveness of eHealth technologies to deliver fall prevention interventions. This protocol describes a systematic review with meta-analysis that aims to evaluate the effect of eHealth fall prevention interventions compared with usual care control on balance in people aged 65 years and older living in the community.Methods and analysisWe will perform a systematic search of the following electronic databases: MEDLINE, CINAHL Complete, Embase and PsychINFO and citation search of Scopus, Web of Science, PubMed Central, Cochrane Database Central and PEDro for randomised controlled trials that use an eHealth technology to deliver a fall prevention intervention to community-dwellers aged ≥65 years, that are published in English, and include a balance outcome (primary outcome). The screening and selection of articles for review will be undertaken by two independent reviewers. The PEDro scale and Grading of Recommendations, Assessment, Development and Evaluations will be used to assess study quality. The results will be synthesised descriptively, and if sufficient data are available and the studies are not overly heterogeneous, a meta-analysis will be conducted using the random effects model.Ethics and disseminationAs this will be a systematic review, without involvement of human participants, there will be no requirement for ethical approval. The results of this systematic review will be disseminated through peer-reviewed publications, conference presentations and dissemination to policymakers and consumers to maximise health impact.PROSPERO registration numberCRD42018115098.
Cost-effectiveness of total knee replacement in addition to non-surgical treatment: a 2-year outcome from a randomised trial in secondary care in Denmark
Authors: Skou Søren Thorgaard , Roos Ewa , Laursen Mogens , Arendt-Nielsen Lars , Rasmussen Sten , Simonsen Ole , Ibsen Rikke , Larsen Arendse T , Kjellberg Jakob 
Published: January 2020

ObjectiveTo assess the 24-month cost-effectiveness of total knee replacement (TKR) plus non-surgical treatment compared with non-surgical treatment with the option of later TKR if needed.Methods100 adults with moderate-to-severe knee osteoarthritis found eligible for TKR by an orthopaedic surgeon in secondary care were randomised to TKR plus 12 weeks of supervised non-surgical treatment (exercise, education, diet, insoles and pain medication) or to supervised non-surgical treatment alone. Including quality-adjusted life years (QALYs) data from baseline, 3, 6, 12 and 24 months, effectiveness was measured as change at 24 months. Healthcare costs and transfer payments were derived from national registries. Incremental healthcare costs, and incremental cost-effectiveness ratios (ICERs) were calculated. A probabilistic sensitivity analysis was conducted and the probability of cost-effectiveness was estimated at the 22 665 Euros/QALY threshold defined by the National Institute for Health and Care Excellence.ResultsTKR plus non-surgical treatment was more expensive (mean of 23 076 vs 14 514 Euros) but also more effective than non-surgical treatment (mean 24-month improvement in QALY of 0.195 vs 0.056). While cost-effective in the unadjusted scenario (ICER of 18 497 Euros/QALY), TKR plus non-surgical treatment was not cost-effective compared with non-surgical treatment with the option of later TKR if needed in the adjusted (age, sex and baseline values), base-case scenario (ICER of 32 611 Euros/QALY) with a probability of cost-effectiveness of 23.2%. Including deaths, TKR plus non-surgical treatment was still not cost-effective (ICERs of 46 277 to 64 208 Euros/QALY).ConclusionsFrom a 24-month perspective, TKR plus non-surgical treatment does not appear to be cost-effective compared with non-surgical treatment with the option of later TKR if needed in patients with moderate-to-severe knee osteoarthritis and moderate intensity pain in secondary care in Denmark. Results were sensitive to changes, highlighting the need for further confirmatory research also assessing the long-term cost-effectiveness of TKR.Trial registration numberClinicalTrials.gov (NCT01410409).
Assessment of fitness for recreational scuba diving in candidates with asthma: a pilot study
Authors: Ustrup Amalie , Pedersen Signe Knag , Suppli Ulrik Charlotte 
Published: January 2020

BackgroundAsthma may be regarded as a contraindication to scuba diving.PurposeA clinical algorithm to assess fitness to dive among individuals with asthma was developed and tested prospectively in clinical practice.Study designCohort study.MethodsAll patients with possible asthma referred to Hvidovre Hospital, Denmark, for assessment of fitness to dive over a 5-year period (2013–2017) were included. Fitness to dive was assessed by case history, spirometry and mannitol challenge test. All patients with ≥10% decline in forced expiratory volume in 1 s (FEV1) (at any point during the challenge test) were offered step-up asthma therapy and rechallenge after at least 3 months. Patients with <10% decline in FEV1after administration of a maximum dose of mannitol at the latest challenge were classified as having no medical contraindications to scuba diving.ResultsThe study cohort comprised 41 patients (24 men; mean age 33 years), of whom 71% and 63% of men and women, respectively, were treated with rescue bronchodilator and inhaled corticosteroid. After the first mannitol challenge test, 21 patients were classified as having no medical contraindications to scuba diving, of whom 16 were currently prescribed asthma medication. After step-up asthma therapy and rechallenge test, an additional seven patients were classified as having no medical contraindications to scuba diving. Overall, using this clinical algorithm, 28 (68%) of the referred patients were finally assessed as having no medical contraindications to scuba diving.ConclusionUsing a clinical algorithm with mannitol challenge to assess fitness to dive among patients with possible asthma and allowing a rechallenge test after step-up asthma therapy increased the proportion of individuals classified as having no medical contraindications to scuba diving. However, as this algorithm has so far not been evaluated against actual scuba diving safety, further studies are clearly needed before it can be implemented with confidence for use in clinical practice.Clinical relevanceAn algorithm to assess fitness for scuba diving among individuals with possible asthma using bronchial challenge test, with the option of step-up asthma therapy and rechallenge for reassessment, has been developed for clinical use.
Scheduled afternoon–evening sleep leads to better night shift performance in older adults
Authors: Isherwood Cheryl Martine , Chinoy Evan D , Murphy Audra S , Kim Jee Hyun , Wang Wei , Duffy Jeanne F 
Published: January 2020

ObjectivesThis study investigated whether an intervention designed to reduce homeostatic sleep pressure would improve night shift performance and alertness in older adults.MethodsNon-shift workers aged 57.9±4.6 (mean±SD) worked four day (07:00–15:00) and four night shifts (23:00–07:00). Two intervention groups were instructed to remain awake until ~13:00 after each night shift: the sleep timing group (ST; n=9) was instructed to spend 8 hours in bed attempting sleep, and the sleep ad-lib group (n=9) was given no further sleep instructions. A control group (n=9) from our previous study was not given any sleep instructions. Hourly Karolinska Sleepiness Scales and Psychomotor Vigilance Tasks assessed subjective sleepiness and performance.ResultsThe ST group maintained their day shift sleep durations on night shifts, whereas the control group slept less. The ST group were able to maintain stable performance and alertness across the initial part of the night shift, while the control group’s alertness and performance declined across the entire night. Wake duration before a night shift negatively impacted sustained attention and self-reported sleepiness but not reaction time, whereas sleep duration before a night shift affected reaction time and ability to sustain attention but not self-reported sleepiness.ConclusionsA behavioural change under the control of the individual worker, spending 8 hours in bed and waking close to the start of the night shift, allowed participants to acquire more sleep and improved performance on the night shift in older adults. Both sleep duration and timing are important factors for night shift performance and self-reported sleepiness.
Maternal occupational exposure to solvents and gastroschisis in offspring - National Birth Defects Prevention Study 1997–2011
Authors: Spinder Nynke , Almli Lynn M , Desrosiers Tania A , Arnold Kathryn E , Bergman Jorieke E H , Kromhout Hans , Boezen H Marike , de Walle Hermien E K , Rocheleau Carissa , Reefhuis Jennita 
Published: January 2020

ObjectivesThe aim of this study was to assess the association between maternal occupational exposure to solvents and gastroschisis in offspring.MethodsWe used data from the National Birth Defects Prevention Study, a large population-based case-control study of major birth defects conducted in 10 US states from 1997 to 2011. Infants with gastroschisis were ascertained by active birth defects surveillance systems. Control infants without major birth defects were selected from vital records or birth hospital records. Self-reported maternal occupational histories were collected by telephone interview. Industrial hygienists reviewed this information to estimate exposure to aromatic, chlorinated and petroleum-based solvents from 1 month before conception through the first trimester of pregnancy. Cumulative exposure to solvents was estimated for the same period accounting for estimated exposure intensity and frequency, job duration and hours worked per week. ORs and 95% CIs were estimated to assess the association between exposure to any solvents or solvent classes, and gastroschisis risk.ResultsAmong 879 cases and 7817 controls, the overall prevalence of periconceptional solvent exposure was 7.3% and 7.4%, respectively. Exposure to any solvent versus no exposure to solvents was not associated with gastroschisis after adjusting for maternal age (OR 1.00, 95% CI 0.75 to 1.32), nor was an association noted for solvent classes. There was no exposure-response relationship between estimated cumulative solvent exposure and gastroschisis after adjusting for maternal age.ConclusionOur study found no association between maternal occupational solvent exposure and gastroschisis in offspring. Further research is needed to understand risk factors for gastroschisis.