bluuebunny/crossref_metadata_2025_split huggingface dataset:
TECHNOLOGY AND LANGUAGE LEARNING: VOCATIONAL HIGH SCHOOL GRADUATE STUDENTS’ PERSPECTIVES ON TOEIC TEST
Authors: Setiawan Budi , Sunardi  , Gunarhadi  , Asrowi  
Published: June 2020

Purpose of the study: This study aims to investigate graduate vocational high school students' perspectives on the use of technology in language learning (e.g., iPad, Personal Data Assistant, computer tablet, and smartphone) for international language testing. Based on the test-takers' data from 2017-2018, the results of the TOEIC score showed continuous descending or unstable performances.
Methodology: It is mixed-method research as the design by involving twenty-five graduate students of vocational high schools situated in Surakarta city. The convenience sampling was taken to cope with the different English proficiency. Open-ended questions and questionnaires become the primary instruments applied to get comprehensive data from them.
Main Findings: The result of this study shows that a self- study and fun condition are achieved by using mobile learning technology to enhance TOEIC language learning. Conducive learning is created, as stated by 92% of graduate students, to project mobile learning to be able to facilitate them in learning TOEIC language proficiency test.
Applications of this study: These findings from this research bring benefits for the vocational high schools, both state and private, as the reference for a further policy of conducting the instructional process in TOEIC language proficiency test to gain projected score required by related workings industry especially in Surakarta city and Indonesia.
Novelty/Originality of this study: As most of the instructional process of TOEIC learning implemented by speech and teacher-centered in the class, the inclusion of technology brings new perspective and paradigm not only effective and efficient way of achieved passing grade score but also allow them to be independent, confident and gain more their problem-solving skill.
THE IMPLEMENTATION OF PROJECT-BASED LEARNING APPROACH IN STUDENTS’ CREATIVITY PROGRAMS IN INDONESIA
Authors: Didin Wahidin , Zubaedah Wiji Lestari 
Published: June 2020

Purpose of the study: This study investigates the implementation of the Project-Based Learning (PjBL) approach through Students’ Creativity Programs (PKM) in Indonesia.
Methodology: The study implemented a qualitative research approach using observation, depth interview, and document analysis as the research instruments.
Principal Findings: The study revealed that PKM had reflected the implementation of Project-Based Learning approach with all its advantages.
Applications of this study: This study reveals that there are many learning approaches with various activities that can effectively use to develop students' critical and creative thinking skills and students' competitiveness, including Project-based Learning rather than traditional instruction. Other than that, hopefully, the results of the PKM and PIMNASin the form of ideas, goods, and services can be utilized by the business and industrial world as it has economic value and benefits to society and can improve the nation's competitiveness.
Novelty: The implementation of Project-Based Learning in students’ massive activity at the national level, known as Students Creativity Programs (PKM) in Indonesia is increasing students’ creativity.
A NEEDS ANALYSIS OF MULTIMEDIA IN THEMATIC LEARNING IN PRIMARY SCHOOLS AS STRENGTHENING CHARACTER EDUCATION
Authors: Prasetyo Giri , Furqon Hidayatullah M. , Akhyar Muhammad , Wiranto  
Published: June 2020

Purpose of the study: The aim of this study to shape Indonesian people who are moral, form Indonesian people who are intelligent and rational, form innovative people who like to work hard, are optimistic and trustworthy, and have a patriot spirit.
Methodology: This research was conducted using a survey method in elementary school teachers, both public and private schools, throughout the Wonogiri district. There were 25 teachers involved in this research. The instrument used was a character education questionnaire, which was adopted from 18 values in the nation's character education. The questions used consisted of four indicators, including teaching materials, the use of multimedia, character education in learning, and the integration of character education in multimedia learning.
Main Findings: The results showed that multimedia learning used by teachers had not integrated the values of Pancasila. While the results of character education analysis, to show that some character values have been applied in learning.
Applications of this study: The implication of the research results can be utilized for further research, in the context of strengthening character education is an educational policy whose main purpose is to implement the Nawacita of President JokoWidodo - JusufKalla in the national education system.
Novelty/Originality of this study: The study of the Value of Character Education in thematic learning is one of the innovations that is being developed theoretically so that multimedia will be created that will strengthen the value of character education. Character values that have not been maximally implemented are creative values, national spirit, discipline, and an attitude of respect for achievement.
Importancia clínica de la arteria umbilical única (A.U.U.)
Authors: Bueno Miguel , Rey Humberto , De la Cruz Jairo , McMurray David 
Published: June 2020

Se presentan nueve casos de arteria umbilical única (A.U.U.), investigados entre 3.136 recién nacidos. Tal hallazgo coexiste en dos casos con malformaciones congénitas importantes demostradas de acuerdo con lo observado con anterioridad por otros autores. Por lo anterior se aconseja encacillar tales casos como casos de alto riesgo y proceder en consecuencia. La presencia de alteraciones halladas en los valores de inmunoglobulina y en el estudio cromosómico reafirma el concepto de que en tales casos influye un factor de alteración embrionaria.
Left-Handedness Among Orthopaedic Surgeons and Trainees
Authors: Sabharwal Samir , MacKenzie James S. , Sterling Robert S. , Ficke James R. , LaPorte Dawn M. 
Published: June 2020

Background:
The impact of left-handedness on orthopaedic surgeons and trainees has not been well described. We investigated the prevalence and perceived impact of left-handedness among orthopaedic surgeons and trainees.

Methods:
We distributed a survey regarding handedness to active members of the American Orthopaedic Association and the Council of Orthopaedic Residency Directors affiliates, including department chairs, program directors, and residency and fellowship program coordinators. Program coordinators were asked to distribute the survey to their current residents and fellows.

Results:
Of 510 survey respondents, 78 (15%) were identified as left hand dominant (LHD). Regarding scalpel/cautery use, 64% of LHD respondents reported using their left hand primarily and 10% reported using their right hand primarily; 26% of LHD respondents described themselves as ambidextrous in scalpel/cautery use, compared with 4.7% of right hand dominant (RHD) respondents (p < 0.001). Regarding suturing, 53% of LHD respondents reported using their left hand primarily and 38% reported using their right hand primarily; 9.0% of LHD respondents described themselves as ambidextrous when suturing, compared with 1.9% of RHD respondents (p = 0.012). Only 5.1% of LHD respondents reported having received laterality-specific psychomotor training, whereas 17% perceived a need for such training during residency; RHD respondents reported similar rates. Ambidexterity in scalpel/cautery use or suturing among LHD respondents was not associated with the perception that their left-handedness was advantageous. LHD attending surgeons were more likely than LHD trainees to perceive their handedness as advantageous (p = 0.007).

Conclusions:
Fifteen percent of orthopaedic surgeons and trainees who responded to our survey were LHD. LHD respondents reported significantly higher rates of ambidexterity in both scalpel/cautery use and suturing compared with RHD respondents. Ambidexterity was not associated with a self-perception that left-handedness was advantageous. LHD-attending surgeons were significantly more likely than LHD residents/fellows to perceive their left-handedness as advantageous. There may be benefits to pairing LHD residents with LHD faculty surgeons early in their training to provide mentorship and insight regarding performing surgical procedures left handed.

Level of Evidence:
Level IV.
Denis J. J. Robichaud, Plato’s Persona: Marsilio Ficino, Renaissance Humanism, and Platonic Traditions, University of Pennsylvania Press, Philadelphia 2018.
Authors: Rees Valery 
Published: June 2020

Review of: Denis J. J. Robichaud, Plato’s Persona: Marsilio Ficino, Renaissance Humanism, and Platonic Traditions, University of Pennsylvania Press, Philadelphia 2018, 344 pp., ISBN 9780812249859.
La trasmissione dell’'ars dialectica' tra i secoli XV e XVI: Lorenzo Valla e Pierre de la Ramée
Authors: Salsano Michela 
Published: June 2020

This essay addresses the theme of the transmission of knowledge starting from the process of traslatio studiorum. Such phenomenon – which occurred between the ancient Greece and occidental Europe since the medieval period – was intended as the triggering phenomenon of a whole series of transmission processes, persisted untill the Renaissance. It is my intention to propose a double riding, considering the Mediterranean area as a transient space, where different current of thoughts have been screened by speculative and linguistical filters, represented by the overlapping of commentators and translators.
On first place, I intend to identify this phenomenon of knowledge's transmission, understood as transcultural process, taken in his historical connotation, that is as a process that commutes from one century to another. Secondly, considering the Arabic intervention concerning the translation and comment of Aristotelian auctoritates, I would like to analyze the delicate process of transmission and contamination between different systems of thought. Within these coordinates, it is my intention to focus on the contact between two systems of thought that applied such approaches in the Dialectic field, namely Lorenzo Valla's and Pierre de la Ramée's, better known as Petrus Ramus. I will take the cases of Valla and Ramus as examples of this phenomenon of translation: first, in the historical sense, since there is a shift of approach from century to century; secondly, in a geographical sense that affects the Mediterranean area, as both Valla and Ramus dealth with the linguistic problems linked to dialectic received from the Arabic heritage. I argue that these speculative currents might have come into contact, first, as the product of a long process of translatio studiorum, and then, as heirs of a tradition that had been influenced by the transmissions that had taken place in the Mediterranean.
In conclusion, the purpose of this note is to show the preliminary and little debated issue of the possible contact between two paradigms of thought which justified a change in the approach of the study of Dialectic between the major Italian centers of knowledge of the XV century and XVI century Paris. This creates the space for some hints of acclimatization of Valla's dialectic at the Ramus paradigm, thanks to the shifting of attention from the perfectly solid linguistic practice in Valla's logical philological method to the correct procedures of reasoning that were completely detached from the metaphysics dimension and projected towards the institution of the Methodus.
Lisa Devriese (ed.), Physiognomonica. Translatio Bartholomaei de Messana, Brepols Publishers, Turnhout 2019 (Corpus Philosophorum Medii Aevi. Aristoteles Latinus, XIX).
Authors: Rossi Pietro Bassiano 
Published: June 2020

Review of: Lisa Devriese (ed.), Physiognomonica. Translatio Bartholomaei de Messana, Brepols Publishers, Turnhout 2019 (Corpus Philosophorum Medii Aevi. Aristoteles Latinus, XIX), CX + 74 pp., ISBN 9782503585673.
iTRAQ-based Comparative Proteomic Analysis of Flag Leaves of Two Wheat (Triticum aestivum L.) Genotypes Differing in Waterlogging Tolerance at Anthesis
Authors: Wei Mingmei , Li LiuLong , Xie Ke , Yang Rui , Wang Xiaoyan , Sha Aihua 
Published: June 2020

Abstract
Background: Waterlogging is one of the major abiotic stresses limiting wheat product. Plants can adapt to waterlogging with changes in morphology, anatomy, and metabolism. Many genes and proteins play critical roles in adaptation to waterlogging. Results: the iTRAQ-based proteomic strategy was applied to identify the waterlogging-responsive proteins in wheat. A total of 4,999 unique proteins were identified in two wheat varieties, XM55 (waterlogging-tolerant) and YM158 (waterlogging-sensitive), at anthesis under waterlogging or not. Sixteen proteins were differentially accumulated between XM55 and YM158 under waterlogging with cultivar specificity. Of these, 11 proteins were up-regulated and 5 proteins were down-regulated. The up-regulated proteins included Fe-S cluster assembly factor, heat shock cognate 70, GTP-binding protein SAR1A-like, and CBS domain-containing protein. The down-regulated proteins contained photosystem II reaction center protein H, carotenoid 9,10 (9',10')-cleavage dioxygenase-like, psbP-like protein 1, and mitochondrial ATPase inhibitor. In addition, 9 proteins were responsive to waterlogging with non-cultivar specificity. These proteins included 3-isopropylmalate dehydratase large subunit, solanesyl-diphosphate synthase 2, DEAD-box ATP-dependent RNA helicase 3, and 3 predicted or uncharacterized proteins. Conclusions: This study revealed that the proteins were differential accumulated between the two contrast waterlogging wheat varieties in response to waterlogging, which provide valuable insights into wheat response to waterlogging stress. These differentially accumulated proteins might be applied to develop waterlogging tolerant wheat in further breeding programs.
Video-based Stained Glass
Authors: Kang Dongwann , Lee Taemin , Shin Yong-Hyeon , Seo Sanghyun 
Published: June 2020

Abstract
This paper presents a method to generate stained-glass animation from video inputs. The method initially segments an input video volume into several regions considered as fragments of glass by mean-shift segmentation. However, the segmentation predominantly results in over-segmentation, causing several tiny segments in a highly textured area. In practice, assembling significantly tiny or large glass fragments is avoided to ensure architectural stability in stained glass manufacturing. Therefore, we use low-frequency components in the segmentation to prevent over-segmentation and subdivide segmented regions that are oversized. The subdividing must be coherent between adjacent frames to prevent temporal artefacts, such as flickering and the shower door effect. To temporally subdivide regions coherently, we obtain a panoramic image from the segmented regions in input frames, subdivide it using a weighted Voronoi diagram, and thereafter project the subdivided regions onto the input frames. To render stained glass fragment for each coherent region, we determine the optimal match glass fragment for the region from a dataset consisting of real stained-glass fragment images and transfer its color and texture to the region. Finally, applying lead came at the boundary of the regions in each frame yields temporally coherent stained-glass animation.
Impact of adding&nbsp;midazolam to bupivacaine 0.5% in regional spinal anesthesia on maternal middle cerebral artery velocimetry &nbsp;in parturients with severe preclampsia
Authors: Raouf mina maher , mikhail Hany Kamal , amin mohammad ahmed , magdy samar mahamad 
Published: June 2020

Abstract
Severe preclampsia is a challenging issue facing both intensivist and anesthetic team carrying both maternal and fetal morbidity and mortality. Termination of pregnancy after blood pressure control is the golden key in management. Cerebral complications due to diffuse cerebral vasospasm are most common and serious. Intrathecal midazolam with its gamma amino butyric action may antidote glutamate mediated sympathetic surge and decreasing cererbral vasospasm. Temporal view transcranial doppler imaging maternal middle cerebral artery is used to examine Blood flow indices namely pulsatality index and resisitive index. One hundered Ladies with severe preclampsia scheduled for urgent caeserian section were recruited in 2 groups, both received 10mg bupivacaine 0.5%, Midazolam group received 1mg midazolam and the other group received 0.2ml sterile saline 0.9% NaCl. All vascular indices were significantly better in midazolam group, less ICU stay.
Prolonged stretching in the late-late pregnant rat uterus inhibits contractions through potassium channel TREK-1
Authors: Yin Zongzhi , Li Yun , Li Dan , Su Jingjing , Shen Bing , Yang Yuanyuan , Cao Yunxia 
Published: June 2020

Abstract
Background

Prolonged stretching can inhibit myometrial contractions in the nonpregnant and the mid- and late-term pregnant uteri of rats and humans through potassium channel TREK-1. What happens in the pregnant uterus close to parturition remains unknown.
Methods

Uterine tissues from late-late pregnant rats (day 20–21 of pregnancy) were isolated, and myometrial strips were prepared for isometric contraction measurements. We compared the oxytocin-induced contractions of myometrial strips treated with different stretch times and doses. Then, we used the potassium channel TREK-1 inhibitor L-methionine and TREK-1 agonist arachidonic acid to determine whether the changes caused by prolonged stretching involved changes in TREK-1 activity.
Results

Prolonged stretching caused relaxation of the myometrial strips that were close to parturition. Additionally, TREK-1 inhibition partly reversed the myometrial relaxation caused by prolonged stretching of the late-late pregnant rat uterus, while TREK-1 activation resulted in a dramatic myometrial contraction change.
Conclusions

Prolonged stretching can inhibit myometrial contractility and induce myometrial relaxation in late-late pregnancy. This contractile inhibition is partly due to functional upregulation of potassium channel TREK-1.
Long Noncoding RNA LINC00858 Promotes the Progression of Ovarian Cancer via Regulating the miR-134-5p/TRIM44 Axis
Authors: Wang Ning , Cao Qin-Xue , Tian Jun , Ren Lu , Cheng Hai-Ling , Yang Shao-Qin 
Published: June 2020

Abstract
Background

Ovarian cancer remains one of the most challenging areas of cancer research. Recent studies have shown that many long non-coding RNAs (lncRNAs) are abnormally expressed in ovarian cancer and involved in the pathological progress of ovarian cancer. In the present study, we aimed to investigate the role of lncRNA LINC00858 and the potential mechanism in ovarian cancer.
Methods

The qRT-PCR was used to measure the expression levels of LINC00858 and miR-134-5p in ovarian cancer tissue specimens and cell lines. Loss-of-function assays were performed to investigate the role of LINC00858 in ovarian cancer progression. MTT assay was carried out to measure cell proliferation. Transwell assays were performed to determine the migration and invasion of ovarian cancer cells. Biological information analysis and luciferase report gene assay were used to verify potential downstream genes of LINC00858. The xenograft mouse model was established to analyze tumor growth in vivo.
Results

Our results showed that LINC00858 was highly expressed in human ovarian cancer tissue specimens and cell lines. Loss-of-function assays showed that knockdown of LINC00858 significantly inhibited cell proliferation, migration and invasion of SKOV3 cells, and suppressed tumor growth in mouse xenograft models. Mechanistic studies revealed that LINC00858 acted as a sponge of miR-134-5p and then regulated the expression TRIM44 in SKOV3 cells. Furthermore, rescue experiments illustrated that inhibition of miR-134-5p restored the inhibitory effects of LINC00858 knockdown on ovarian cancer cell proliferation, migration and invasion. TRIM44 overexpression could counteract the inhibitory effects of miR-134-5p mimics on ovarian cancer cells.
Conclusion

In conclusion, these findings demonstrated that LINC00858 exerted oncogenic role in ovarian cancer, which was mediated by miR-134-5p/TRIM44 axis. Thus, LINC00858 might be a therapeutic target for the treatment of ovarian cancer.
Association of Alanine Transaminase to Aspartate Aminotransferase Ratio and Incident Diabetes in Chinese Adults: A Second Retrospective Cohort Study
Authors: Liang Zhilin , Hu Haofei , Wang Xunxun , Chen Xianxiong , Liu Zhigang , Zhang Min 
Published: June 2020

Abstract
Background

Previous studies have indicated that serum alanine aminotransferase (ALT) level, serum aspartate aminotransferase (AST) level or ALT/AST ratio may be bound up with diabetes. But the association of ALT/AST ratio and incident diabetes in Chinese adults have not been elaborated yet. The main objective of the present study was to analyze whether ALT/AST ratio was an independent risk factor which attached to the risk of incident diabetes in Chinese adults.
Methods

From 2010 to 2016, 685,277 Chinese adults who received a health check in Rich Healthcare Group including all medical records, and the present article was a second retrospective cohort analysis based on above population. As the target independent variable, ALT/AST ratio was measured at baseline while the dependent variable, incident diabetes appeared during follow-up. We used Cox proportional hazard regression models to analyze the prognostic value of ALT/AST on the risk of incident diabetes.
Results

ALT/AST demonstrated undeniable correlation with incident diabetes (HR = 2.535, 95%CI: 2.190 to 2.934, P < 0.00001). The association between ALT/AST and incident diabetes is only linear. The cumulative incidence (95% CI) rate of incident diabetes in total participants, ALT/AST quartile 1, 2, 3, and 4 was 2.112 (2.016–2.208), 0.992 (.0.857–1.127), 1.430 (1.274–1.586), 2.396 (2.192-2.600) and 3.559 (3.314–3.803), separately. The population with age (30 to < 40 years), BMI (< 24 kg/m2) and SBP (< 140 mmHg) was found to be the stronger association in subgroup analysis.
Conclusion

In Chinese adults, ALT/AST ratio is an independent risk factor for incident diabetes.