bluuebunny/crossref_metadata_2025_split huggingface dataset:
Noninvasive 7 tesla MRI of fatal craniocerebral gunshots – a glance into the future of radiologic wound ballistics
Authors: Gascho Dominic , Deininger-Czermak Eva , Zoelch Niklaus , Tappero Carlo , Sommer Stefan , Hinterholzer Natalie , Thali Michael J 
Published: September 2020

AbstractCompared to computed tomography (CT), magnetic resonance imaging (MRI) provides superior visualization of the soft tissue. Recently, the first 7 Tesla (7 T) MRI scanner was approved for clinical use, which will facilitate access to these ultra-high-field MRI scanners for noninvasive examinations and scientific studies on decedents. 7 T MRI has the potential to provide a higher signal-to-noise ratio (SNR), a characteristic that can be directly exploited to improve image quality and invest in attempts to increase resolution. Therefore, evaluating the diagnostic potential of 7 T MRI for forensic purposes, such as assessments of fatal gunshot wounds, was deemed essential. In this article, we present radiologic findings obtained for craniocerebral gunshot wounds in three decedents. The decedents were submitted to MRI examinations using a 7 T MRI scanner that has been approved for clinical use and a clinical 3 T MRI scanner for comparison. We focused on detecting tiny injuries beyond the wound tract caused by temporary cavitation, such as microbleeds. Additionally, 7 T T2-weighted MRI highlighted a dark (hypo intense) zone beyond the permanent wound tract, which was attributed to increased amounts of paramagnetic blood components in damaged tissue. Microbleeds were also detected adjacent to the wound tract in the white matter on 7 T MRI. Based on the findings of radiologic assessments, the advantages and disadvantages of postmortem 7 T MRI compared to 3 T MRI are discussed with regard to investigations of craniocerebral gunshot wounds as well as the potential role of 7 T MRI in the future of forensic science.
Epidemiological and Clinical Patterns of Newly Diagnosed Hepatocellular Carcinoma in Brazil: the Need for Liver Disease Screening Programs Based on Real-World Data
Authors: Fernandes Gustavo dos Santos , Campos Daniel , Ballalai Andre , Palhares Rodrigo , da Silva Mario R. A. , Palhares Daniel M. F. , Neto Ben-Hur F. , Barros Fabio M. do R. , Gil Roberto de A. , Chagas Aline , Carrilho Flair José 
Published: September 2020

Abstract
Purpose
Describe sociodemographic and clinical characteristics of patients with hepatocellular carcinoma (HCC) and establish their history in the Brazilian public health system.

Methods
Retrospective observational study was conducted using the database from the Department of Informatics of the Unified Health System (DataSUS). Patients with at least one claim of HCC between July/2011 and June/2016 were included. A record linkage methodology was performed to obtain longitudinal data across different databases. Demographic and clinical data were evaluated, including the time elapsed between diagnosis of HCC risk-factors and the cancer development. Data was analyzed using descriptive statistics.

Results
A total of 28,822 HCC cases were identified between July/2011 and June/2016. Mean age was 59.7 years (SD = 14.7), and most patients were men (55.9%). The highest relative number of HCC cases was detected in the south of Brazil (> 20 cases/100,000 inhabitants). About 86.5% of the patients had diagnosis of HCC without previous liver diseases. Only 8% had diagnosis of chronic viral hepatitis and 3.5% cirrhosis. About 76% were diagnosed at an advanced stage, and only 11% of the patients had early stage HCC. Approximately 58% of patients with previous underlying liver diseases were diagnosed at early stages, compared with only 24% of patients without prior record of underlying diseases.

Conclusion
The diagnosis of HCC in the Brazilian public health is usually made in patients with no previous diagnosis of liver disease and in advanced stages, when no curative treatment is available and survival rates are low. Public health policies are key for the screening and monitoring liver disease and, consequently, HCC.
The Aporia of Future Directed Beliefs
Authors: Rönnedal Daniel 
Published: September 2020

AbstractThis paper discusses a new aporia, the aporia of future directed beliefs. This aporia contains three propositions: (1) It is possible that there is someone who is infallible that believes something about the future that is not historically settled, (2) it is necessary that someone is infallible if and only if it is necessary that everything she believes is true, and (3) it is necessary that all our beliefs are historically settled. Every claim in this set is intuitively plausible, and there are interesting arguments for or against each of them. Nevertheless, {(1), (2), (3)} entails a contradiction. Consequently, at least one of the sentences in this set must be false. I consider some possible solutions to the problem and discuss some arguments for and against these solutions. Five solutions, in particular, stand out. Three solutions reject (1), one solution rejects (2), and one solution rejects (3). No solution is without problems, and it is not obvious which one we should choose. Yet, we have to give up at least one sentence in {(1), (2), (3)}. This is the nature of an aporia.
Bulk and molecular composition variations of gold-tube pyrolysates from severely biodegraded Athabasca bitumen
Authors: Li Zhong-Xuan , Huang Hai-Ping 
Published: September 2020

AbstractGold-tube pyrolysis experiments were performed on two Athabasca oil sand bitumens at 300 °C to 525 °C with 2 °C/h rate and 25 °C step under 50 MPa. Pyrolysis temperature of 425 °C is critical for weight loss of bulk bitumen and hydrocarbon generation and destruction. Polar compounds are the main source of saturated and aromatic hydrocarbon, gas and coke fractions. Molecular compositions in pyrolyzates vary systematically with increasing pyrolysis temperatures. High molecular weight n-alkanes (C26+) are gradually destructed during pyrolysis due to thermal cracking. Moderate molecular weight n-alkanes (C21–C25) show the highest thermal stability in designed pyrolysis temperatures. The loss of low molecular weight n-alkanes (C20−) might be caused by volatilization during pyrolysis, which may alter commonly used molecular parameters such as ∑n-C20−/∑n-C21+, Pr/n-C17 and Ph/n-C18. Aromatic hydrocarbons were generated from 300 to 425 °C, then condensation and dealkylation have been initiated at 425 °C as evidenced by decreased summed alkylnaphthalenes to alkylphenanthrenes ratios and increased unsubstituted aromatics to substituted homologs ratios in higher temperatures. The occurrence of anthracene and benz[a]anthracene in pyrolysates indicates pyrogenic origin, while fluoranthene shows unexpected behaviors during pyrolysis. Ratios derived from them are not always reliable for pyrogenic source input diagnosis in environmental samples.
Coarse and fine-tuning of lasing transverse electromagnetic modes in coupled all-inorganic perovskite quantum dots
Authors: Park Youngsin , Ying Guanhua , Jana Atanu , Osokin Vitaly , Kocher Claudius C. , Farrow Tristan , Taylor Robert A. , Kim Kwang S. 
Published: September 2020

AbstractInorganic perovskite lasers are of particular interest, with much recent work focusing on Fabry-Pérot cavity-forming nanowires. We demonstrate the direct observation of lasing from transverse electromagnetic (TEM) modes with a long coherence time ∼ 9.5 ps in coupled CsPbBr3 quantum dots, which dispense with an external cavity resonator and show how the wavelength of the modes can be controlled via two independent tuning-mechanisms. Controlling the pump power allowed us to fine-tune the TEM mode structure to the emission wavelength, thus providing a degree of control over the properties of the lasing signal. The temperature-tuning provided an additional degree of control over the wavelength of the lasing peak, importantly, maintained a constant full width at half maximum (FWHM) over the entire tuning range without mode-hopping.
Distributed Fiber Birefringence Measurement Using Pulse-Compression Φ-OTDR
Authors: Chen Yongxiang , Fu Yun , Xiong Ji , Wang Zinan 
Published: September 2020

AbstractIn this paper, a novel birefringence measurement method through the Rayleigh backscattered lightwave within single-mode fiber is proposed, using a single chirped-pulse with arbitrary state of polarization. Numerical analysis is carried out in detail, then pulse-compression phase-sensitive optical time domain reflectometry (PC-Φ-OTDR) with polarization-diverse coherent detection is employed to verify this method. A 2km spun single-mode fiber is tested with 8.6 cm spatial resolution, and the average birefringence of the fiber under test is measured as 0.234rad/m, which is consistent with previous literatures about single-mode fiber. Moreover, the relationship between the measured birefringence and the spatial resolution is also studied for the first time, and the results show that spatial resolution is crucial for fiber birefringence measurement.
Biological treatment of leachate from stabilization of biodegradable municipal solid waste in a sequencing batch biofilm reactor
Authors: Bernat K. , Zaborowska M. , Zielińska M. , Wojnowska-Baryła I. , Ignalewski W. 
Published: September 2020

AbstractThe aim of this study was to determine the effectiveness of pollutant removal in sequencing batch biofilm reactors (with floating or submerged carriers) when treating nitrogen- and organic-rich real leachate generated during aerobic stabilization of the biodegradable municipal solid waste. A control reactor contained suspended activated sludge. The share of leachate in synthetic wastewater was 10%, which resulted in ratios of chemical oxygen demand and biochemical oxygen demand to total Kjeldahl nitrogen in the influent of ca. 11 and ca. 8.5, respectively. Regardless of whether the reactors contained carriers or not, the effectiveness of nitrification (84.2–84.3%) and of the removal of chemical oxygen demand (86.5–87.0%), biochemical oxygen demand (95.5–98.0%) and ammonium (88.9–89.3%) did not differ. However, the presence of carriers and their type determined in which phase of the cycle denitrification occurred. In the control reactor, denitrification took place during mixing phase with the effectiveness of ca. 43.2% (57.7% of the total nitrogen removal). During aeration, the oxygen content increased rapidly, thus reduced the possibility of simultaneous denitrification. In reactors with carriers, in the aeration phase, not only nitrification but also denitrification occurred. The increase in oxygen content in wastewater was slower, which could have caused dissolved oxygen gradients and anoxic zones in deeper layers of the biofilm and flocks. In the reactor with floating carriers, the effectiveness of denitrification and total nitrogen removal increased 1.23- and 1.10-times, respectively, as compared to the control reactor. The highest efficiencies (67.7% and 73.0%, respectively) were observed in the reactor with submerged carriers.
Zn2+ substituted superparamagnetic MgFe2O4 spinel-ferrites: Investigations on structural and spin-interactions
Authors: Phor Lakshita , Chahal Surjeet , Kumar Vinod 
Published: September 2020

AbstractNano-magnetic ferrites with composition Mg1−xZnxFe2O4 (x = 0.3, 0.4, 0.5, 0.6, and 0.7) have been prepared by coprecipitation method. X-ray diffraction (XRD) studies showed that the lattice parameter was found to increase from 8.402 to 8.424 Å with Zn2+ ion content from 0.3 to 0.7. Fourier transform infrared (FTIR) spectra revealed two prominent peaks corresponding to tetrahedral and octahedral at around 560 and 430 cm−1 respectively that confirmed the spinel phase of the samples. Transmission electron microscopy (TEM) images showed that the particle size was noted to increase from 18 to 24 nm with an increase in Zn content from x = 0.3 to 0.7. The magnetic properties were studied by vibrating sample magnetometer (VSM) and electron paramagnetic resonance (EPR) which ascertained the superparamagnetic behavior of the samples and contribution of superexchange interactions. The maximum magnetization was found to vary from 23.80 to 32.78 emu/g that increased till x = 0.5 and decreased thereafter. Further, X-ray photoelectron spectroscopy (XPS) was employed to investigate the chemical composition and substantiate their oxidation states.
Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients
Authors: Zuliani Giovanni , Polastri Michele , Romagnoli Tommaso , Marabini Lisa , Seripa Davide , Cervellati Carlo , Zurlo Amedeo , Passaro Angelina , Brombo Gloria 
Published: September 2020

Abstract
Objectives
To evaluate the possibility of predicting the risk of progression from mild cognitive impairment (MCI) to dementia using a combination of clinical/demographic parameters.

Methods
A total of 462 MCI elderly patients (follow-up: 33 months). Variable measured included cognitive functions, age, gender, MCI type, education, comorbidities, clinical chemistry, and functional status.

Results
Amnestic type (aMCI) represented 63% of the sample, non-amnestic (naMCI) 37%; 190 subjects progressed to dementia, 49% among aMCI, and 28% among naMCI. At Cox multivariate regression analysis, only MMSE (one point increase HR 0.84; 95% CI 0.79–0.90), aMCI (HR 2.35; 95% CI 1.39–3.98), and age (1 year increase HR 1.05; 95% CI 1.01–1.10) were independently associated with progression to dementia. A score was created based on these dichotomized variables (score 0–3): age (≥ or < 78 years), MMSE score (≥ or < 25/30) and aMCI type. The conversion rate progressed from 6% in subjects with score 0 (negative predictive value: 0.94), to 31% in individuals with score 1, to 53% in subjects with score 2, to 72% in individuals with score 3 (positive predictive value: 0.72). ROC curve analysis showed an area under the curve of 0.72 (95% CI 0.66–0.75, p 0.0001).

Conclusions
We have described a simple score, based on previously recognized predictors such as age, MMSE, and MCI type, which may be useful for an initial stratification of the risk of progression to dementia in patients affected by MCI. The score might help the clinicians to evaluate the need for more expansive/invasive examinations and for a closer follow-up in MCI patients.
Birth cohort differences in cognitive performance in 75- and 80-year-olds: a comparison of two cohorts over 28 years
Authors: Munukka Matti , Koivunen Kaisa , von Bonsdorff Mikaela , Sipilä Sarianna , Portegijs Erja , Ruoppila Isto , Rantanen Taina 
Published: September 2020

Abstract
Objective
To evaluate cohort differences in cognitive performance in older men and women born and assessed 28 years apart.

Methods
Data in this study were drawn from two age-homogeneous cohorts measured in the same laboratory using the same standardized cognitive performance tests. Participants in the first cohort were born in 1910 and 1914 and assessed in 1989–1990 (Evergreen project, n = 500). Participants in the second cohort were born in 1938 or 1939 and 1942 or 1943 and assessed in 2017–2018 (Evergreen II, n = 726). Participants in both cohorts were assessed at age 75 and 80 years and were recruited from the population register. Cognitive performance was measured using the Digit Span test from the Wechsler Memory Scale (WMS), Digit Symbol test from the Wechsler Adult Intelligence Scale (WAIS) and phonemic Verbal Fluency test from the Schaie-Thurstone Adult Mental Abilities Test. Reaction time assessing motor and mental responses was measured with a simple finger movement task, followed by a complex finger movement task. T-tests were used to study cohort differences and linear regression models to study possible factors underlying differences.

Results
We found statistically significant cohort differences in all the cognitive performance tests, except for the digit span test and simple movement task in men, the later-born cohort performing better in all the measured outcomes.

Conclusions
The results of this study provide strong evidence that cognitive performance is better in more recent cohorts of older people compared to their counterparts measured 28 years earlier.
Prenatal Diagnosis of Right Sided Inguinoscrotal Hernia Associated with Severe Growth Restriction in a Fetus with Trisomy 18: A Case Report
Authors: Seneesh Kumar Vikraman , Elango Nithya , Dubey Aditi 
Published: September 2020

AbstractFetal inguinoscrotal hernia is an uncommon occurence in the prenatal life, and published literature on it is scarce. This is a type of indirect hernia that results from abnormal migration of the small bowel into the scrotum via the patent processus vaginalis. We present a case of prenatal diagnosis of right sided fetal inguinoscrotal hernia, with contralateral hydrocele and severe fetal growth restriction confirmed as Trisomy 18 in subsequently performed chromosomal analysis. The index case presented at 35+2 weeks of gestation with a right sided solid scrotal mass with a regular contour, mixed echogenic texture with a few echo-free areas, a distinctive arterial supply and characteristic peristaltic movements. Fetal demise was noted one week later. The diagnosis was confirmed by postnatal examination. Prenatal diagnosis of fetal inguinoscrotal hernia should be followed up with detailed anatomical assessment and chromosomal analysis if indicated by the presence of additional abnormalities. Isolated cases require surgical repair in the neonatal period to avoid sequelae and complications.
Is There a Role for Plasma Exchange in ANCA-Associated Vasculitis?
Authors: Prendecki Maria , McAdoo Stephen P. , Pusey Charles D. 
Published: September 2020

Abstract
Purpose of review
This review summarises the evidence for the use of therapeutic plasma exchange (TPE) in anti-neutrophil cytoplasm antibody (ANCA)–associated vasculitis. TPE is an extra-corporeal treatment which efficiently removes IgG and other pathogenic small molecules from the blood. There are several mechanistic reasons why this should be of benefit in AAV including the well-described pathogenicity of ANCA.

Recent findings
The recently published PEXIVAS trial is the largest study of TPE in AAV to date. It did not show a benefit for adjunctive TPE on a primary end point of ESRD or death. There was no difference in serious adverse events between those treated with TPE and those treated with immunosuppressive drugs alone.

Conclusions
Based on the results of PEXIVAS, most patients with AAV should not be treated with adjunctive TPE. However, there are subgroups of patients with AAV for whom TPE may still be of benefit, including those with double positivity for anti-GBM antibodies and ANCA.
Machine learning model-based two-dimensional matrix computation model for human motion and dance recovery
Authors: Zhang Yi , Zhang Mengni 
Published: September 2020

AbstractMany regions of human movement capturing are commonly used. Still, it includes a complicated capturing method, and the obtained information contains missing information invariably due to the human's body or clothing structure. Recovery of motion that aims to recover from degraded observation and the underlying complete sequence of motion is still a difficult task, because the nonlinear structure and the filming property is integrated into the movements. Machine learning model based two-dimensional matrix computation (MM-TDMC) approach demonstrates promising performance in short-term motion recovery problems. However, the theoretical guarantee for the recovery of nonlinear movement information lacks in the two-dimensional matrix computation model developed for linear information. To overcome this drawback, this study proposes MM-TDMC for human motion and dance recovery. The advantages of the machine learning-based Two-dimensional matrix computation model for human motion and dance recovery shows extensive experimental results and comparisons with auto-conditioned recurrent neural network, multimodal corpus, low-rank matrix completion, and kinect sensors methods.
Ad5/3 is able to avoid neutralization by binding to erythrocytes and lymphocytes
Authors: Zafar Sadia , Quixabeira Dafne Carolina Alves , Kudling Tatiana Viktorovna , Cervera-Carrascon Victor , Santos Joao Manuel , Grönberg-Vähä-Koskela Susanna , Zhao Fang , Aronen Pasi , Heiniö Camilla , Havunen Riikka , Sorsa Suvi , Kanerva Anna , Hemminki Akseli 
Published: September 2020

AbstractOncolytic adenoviruses are promising cancer therapeutic agents. Clinical data have shown adenoviruses’ ability to transduce tumors after systemic delivery in human cancer patients, despite antibodies. In the present work, we have focused on the interaction of a chimeric adenovirus Ad5/3 with human lymphocytes and human erythrocytes. Ad5/3 binding with human lymphocytes and erythrocytes was observed to occur in a reversible manner, which allowed viral transduction of tumors, and oncolytic potency of Ad5/3 in vitro and in vivo, with or without neutralizing antibodies. Immunodeficient mice bearing xenograft tumors showed enhanced tumor transduction following systemic administration, when Ad5/3 virus was bound to lymphocytes or erythrocytes (P < 0.05). In conclusion, our findings reveal that chimeric Ad5/3 adenovirus reaches non-injected tumors in the presence of neutralizing antibodies: it occurs through reversible binding to lymphocytes and erythrocytes.
Kriging‐based ionospheric TEC, ROTI and amplitude scintillation index (S4) maps for India
Authors: Babu Sree Harsha Pasumarthi , Venkata Ratnam Devanaboyina , Lavanya Nagasri Mutyala , Sridhar Miriyala , Padma Raju Koppireddi 
Published: September 2020

In this study, an attempt is made to develop regional ionospheric total electron content (TEC), rate of TEC index (ROTI) and amplitude scintillation index (S 4) maps using data from 26 dual‐frequency global positioning system (GPS) receivers under GPS aided geo‐stationary earth orbit augmented navigation programme over Indian region. One‐minute spatial TEC maps are generated for the entire Indian region covering 65–100°E geographic longitudes, 5–40°N geographic latitudes with 2° × 2° grid separation using Kriging method. Also, the ROTI and amplitude scintillation index (S 4) maps for every 5 min are generated. The performance of the generated regional TEC maps is evaluated during a severe geomagnetic storm condition. Patterns of equatorial ionisation anomaly (EIA) TEC structures are investigated for St. Patrick's storm between the days 15 and 20 March 2015 with the generated TEC maps. The proposed TEC maps depict the northern crest of EIA features in latitudinal extent and TEC strength. The kriging method detects the suppressed and downshift of EIA features on 18 March 2015. The movement of plasma bubbles are analysed over Indian latitudes during the transition period of a geomagnetic storm on 17 March 2015.
Symmetry properties of non-Hermitian

PT

-symmetric quantum field theories
Authors: Millington P 
Published: September 2020

Abstract
We describe recent progress in understanding the continuous symmetry properties of non-Hermitian,

PT

-symmetric quantum field theories. Focussing on a simple non-Hermitian theory composed of one complex scalar and one complex pseudoscalar, we revisit the derivation of Noether’s theorem to show that the conserved currents of non-Hermitian theories correspond to transformations that do not leave the Lagrangian invariant. We illustrate the impact that this has on the consistent formulation of (Abelian) gauge theories by studying a non-Hermitian extension of scalar quantum electrodynamics. We consider the spontaneous breakdown of both global and local symmetries, and describe how the Goldstone theorem and the Englert-Brout-Higgs mechanism are borne out for non-Hermitian,

PT

-symmetric theories.