bluuebunny/crossref_metadata_2025_split huggingface dataset:
Noncontact Thermal and Vibrotactile Display Using Focused Airborne Ultrasound
Authors: Kamigaki Takaaki , Suzuki Shun , Shinoda Hiroyuki 
Published: September 2020

AbstractIn a typical mid-air haptics system, focused airborne ultrasound provides vibrotactile sensations to localized areas on bare skin. Herein, a method for displaying heat sensations to hands where gloves are worn is proposed. The gloves employed in this study are commercially available gloves with sound absorption characteristics, such as cotton work gloves without any additional devices such as Peltier elements. The method proposed in this study can also provide vibrotactile sensations by changing the ultrasonic irradiation pattern. In this paper, we report basic experimental investigations on the proposed method. By performing thermal measurements, we evaluate the local heat generation on the surfaces of both the glove and the skin by focused airborne ultrasound irradiation. In addition, we performed perceptual experiments, thereby confirming that the proposed method produced both heat and vibrotactile sensations. Furthermore, these sensations were selectively provided to a certain extent by changing the ultrasonic irradiation pattern. These results validate the effectiveness of our method and its feasibility in mid-air haptics applications.
Stiffness Discrimination by Two Fingers with Stochastic Resonance
Authors: Chamnongthai Komi , Endo Takahiro , Ikemura Shohei , Matsuno Fumitoshi 
Published: September 2020

AbstractThis paper focuses on Stochastic Resonance (SR) for stiffness discrimination by two fingers. In particular, we show that the sub-threshold vibrotactile noise applied on a remote position can improve tactile sensations of both index finger and thumb for a task requiring multiple fingers. We evaluate the user performances in a virtual environment (VE) by Weber fraction for stiffness perception under one of three different vibration source positions: on the index finger, on the thumb, and between the index finger and thumb. The results show that the stiffness discrimination ability increase under all three vibration source positions with the best performance obtained for the source location between index finger and thumb. The finding indicates the potential of using a single vibration source to enhance sensation of multiple fingers by the effect of SR.
Two-Point Haptic Pattern Recognition with the Inverse Filter Method
Authors: Pantera Lucie , Hudin Charles , Panëels Sabrina 
Published: September 2020

AbstractTouchscreens are widely used nowadays, yet still crucially lack haptic feedback for a rich interaction. Haptic feedback presents several benefits for touch interactions but can be difficult to achieve on a surface, due to issues of vibration propagation. The Inverse Filter Method enables to achieve localised multitouch haptic feedback on a glass surface by controlling the vibrations field over the entire surface. This recent method could enable a wide range of novel interactions. Yet, it has not been tested with users. This paper presents an initial study evaluating 2-point based pattern recognition using IFM with two fingers from each hand and with different timing difference in presentation, varying from 0 ms to 300 ms. The results are promising as participants could discriminate rather well the different patterns with averaged rates of 83% for simultaneous stimuli and up to 92% for stimuli separated by 300 ms.
Discriminating Between Intensities and Velocities of Mid-Air Haptic Patterns
Authors: Rutten Isa , Frier William , Geerts David 
Published: September 2020

AbstractThis study investigates people’s ability in discriminating between different intensities and velocities of mid-air haptic (MAH) sensations. Apart from estimating the just noticeable differences (JND), we also investigated the impact of age on discrimination performance, and the relationship between someone’s confidence in his/her performance and the actual discrimination performance. In an experimental set-up, involving 50 participants, we obtained a JND of 12.12% for intensities and 0.51 rev/s for velocities. Surprisingly, the impact of age on discrimination performance was only small and almost negligible. Furthermore, participants’ subjective perception of their discrimination performance aligned well with their actual discrimination performance. These results are encouraging for the use of intensities and velocities as dimensions in the design of MAH patterns to convey information to the user.
J/ψ meson production in SIDIS: matching high and low transverse momentum
Authors: Boer Daniël , D’Alesio Umberto , Murgia Francesco , Pisano Cristian , Taels Pieter 
Published: September 2020

Abstract
We consider the transverse momentum spectrum and the cos 2ϕ azimuthal distribution of J/ψ mesons produced in semi-inclusive, deep-inelastic electron-proton scattering, where the electron and the proton are unpolarized. At low transverse momentum, we propose factorized expressions in terms of transverse momentum dependent gluon distributions and shape functions. We show that our formulae, at the order αs, correctly match with the collinear factorization results at high transverse momentum. The latter are computed at the order $$ {\alpha}_s^2 $$

α
s
2

in the framework of nonrelativistic QCD (NRQCD), with the inclusion of the intermediate $$ {}^3{S}_1^{\left[1\right]} $$

3

S
1

1

color-singlet Fock state, as well as the subleading color-octet ones that are relatively suppressed by a factor v4 in the NRQCD velocity parameter v. We show that the $$ {}^1{S}_0^{\left[8\right]} $$

1

S
0

8

and $$ {}^3{P}_J^{\left[8\right]} $$

3

P
J

8

(J = 0, 1, 2) contributions diverge in the small transverse momentum region and allow us to determine the perturbative tails of the shape functions, which carry the same quantum numbers. These turn out to be identical, except for the overall magnitude given by the appropriate NRQCD long distance matrix element.
In-Flow and Out-Flow Problem for the Stokes System
Authors: Nowakowski Bernard , Ströhmer Gerhard 
Published: September 2020

AbstractWe investigate the existence and regularity of solutions to the stationary Stokes system and non-stationary Navier–Stokes equations in three dimensional bounded domains with in- and out-lets. We assume that on the in- and out-flow parts of the boundary the pressure is prescribed and the tangential component of the velocity field is zero, whereas on the lateral part of the boundary the fluid is at rest.
“Why not ask the doctor?” Barriers in help-seeking for sexual problems among older adults in Poland
Authors: Gore-Gorszewska Gabriela 
Published: September 2020

Abstract

Objectives
Existing data show that older adults rarely seek medical or psychological help for their sexual problems. The current study explores the barriers in help-seeking faced by older adults from a conservative Central European country.

Methods
Thirty semi-structured interviews were conducted among Polish residents (16 women, 14 men) aged 65–82. The data were analysed thematically, with coding validity and analytical rigour ensured throughout the process.

Results
Three main barriers in seeking help were identified: not recognising sexual problems; fear for the doctors’ disapproval; lack of knowledge how to access appropriate services. The data reveal that the participants’ main concern is that health providers would dismiss their problems as trivial. Older adults from Poland suffer from the lack of fundamental knowledge about their sexual functioning.

Conclusions
Employing qualitative methodology to understand why older adults from conservative cultures do not seek help for their sexual problems might contribute to existing literature by providing evidence from different cultural settings, and help to develop and implement appropriate interventions. Implications related to health providers’ attitude towards older patients’ concerns are further discussed.
Biodynamic timber sheet pile walls: vegetation retaining structure
Authors: Kamath Abhijith , Gard Wolfgang , Van de Kuilen Jan-Willem 
Published: September 2020

AbstractTimber sheet pile walls are widely used for the protection of stream banks in different parts of the world. However, there is a tendency to create more sustainable types of stream banks not only because exploitable wood is more difficult to obtain, but also because of disturbance to the natural habitat of plants and animals due to hard embankments. In the Netherlands alone, about 2500 km of engineered timber sheet pile wall embankments exist, primarily made with tropical hardwood, besides an even much larger amount of ‘non-engineered’ small-size timber-based embankments. As an alternative, the authors propose to use a mixed timber sheet pile-vegetation system, where locally available timber can be applied in combination with natural vegetation. Unlike the usual bioengineering scheme, vegetation is not seen as an element, which could replace the timber sheet piles. Instead, a new perspective is tested, where the vegetation is included as a ‘structural’ element which can even counteract the consequences of time-dependent biological degradation of the timber sheet pile. By doing so, both long-term durability as well as reliability of the stream bank is improved. A comprehensive design strategy was developed based on well-established sub-models from the literature on plant growth, root reinforcement as well as timber damage accumulation. The timber sheet pile wall-vegetation system is illustrated in an example case study. Preliminary analysis including only the mechanical reinforcement of vegetation shows that there is a decrease in moment and shear acting on the timber sheet pile with growth of the vegetation. Consequently, the damage accumulation due to load duration effects on the timber decreases and the service life of the system increases. Thus, using vegetation in combination with highly degradable timber could possibly negate the need for using hardwood timber, or more generally, save resources that are currently used for these structures.
Dissociable dopaminergic and pavlovian influences in goal-trackers and sign-trackers on a model of compulsive checking in OCD
Authors: Eagle D. M. , Schepisi C. , Chugh S. , Desai S. , Han S. Y. S. , Huang T. , Lee J. J. , Sobala C. , Ye W. , Milton A. L. , Robbins T. W. 
Published: September 2020

Abstract
Rationale
Checking is a functional behaviour that provides information to guide behaviour. However, in obsessive-compulsive disorder (OCD), checking may escalate to dysfunctional levels. The processes underpinning the transition from functional to dysfunctional checking are unclear but may be associated with individual differences that support the development of maladaptive behaviour. We examined one such predisposition, sign-tracking to a pavlovian conditioned stimulus, which we previously found associated with dysfunctional checking. How sign-tracking interacts with another treatment with emerging translational validity for OCD-like checking, chronic administration of the dopamine D2 receptor agonist quinpirole, is unknown.

Objectives
We tested how functional and dysfunctional checking in the rat observing response task (ORT) was affected by chronic quinpirole administration in non-autoshaped controls and autoshaped animals classified as sign-trackers or goal-trackers.

Methods
Sign-trackers or goal-trackers were trained on the ORT before the effects of chronic quinpirole administration on checking were assessed. Subsequently, the effects on checking of different behavioural challenges, including reward omission and the use of unpredictable reinforcement schedules, were tested.

Results
Prior autoshaping increased checking. Sign-trackers and goal-trackers responded differently to quinpirole sensitization, reward omission and reinforcement uncertainty. Sign-trackers showed greater elevations in dysfunctional checking, particularly during uncertainty. By contrast, goal-trackers predominantly increased functional checking responses, possibly in response to reduced discrimination accuracy in the absence of cues signalling which lever was currently active.

Conclusions
The results are discussed in terms of how pavlovian associations influence behaviour that becomes compulsive in OCD and how this may be dependent on striatal dopamine D2 receptors.
Physiologically based pharmacokinetic modeling to assess metabolic drug–drug interaction risks and inform the drug label for fedratinib
Authors: Wu Fan , Krishna Gopal , Surapaneni Sekhar 
Published: September 2020

Abstract
Purpose
Fedratinib (INREBIC®), a Janus kinase 2 inhibitor, is approved in the United States to treat patients with myelofibrosis. Fedratinib is not only a substrate of cytochrome P450 (CYP) enzymes, but also exhibits complex auto-inhibition, time-dependent inhibition, or mixed inhibition/induction of CYP enzymes including CYP3A. Therefore, a mechanistic modeling approach was used to characterize pharmacokinetic (PK) properties and assess drug–drug interaction (DDI) potentials for fedratinib under clinical scenarios.

Methods
The physiologically based pharmacokinetic (PBPK) model of fedratinib was constructed in Simcyp® (V17R1) by integrating available in vitro and in vivo information and was further parameterized and validated by using clinical PK data.

Results
The validated PBPK model was applied to predict DDIs between fedratinib and CYP modulators or substrates. The model simulations indicated that the fedratinib-as-victim DDI extent in terms of geometric mean area under curve (AUC) at steady state is about twofold or 1.2-fold when strong or moderate CYP3A4 inhibitors, respectively, are co-administered with repeated doses of fedratinib. In addition, the PBPK model successfully captured the perpetrator DDI effect of fedratinib on a sensitive CY3A4 substrate midazolam and predicted minor effects of fedratinib on CYP2C8/9 substrates.

Conclusions
The PBPK-DDI model of fedratinib facilitated drug development by identifying DDI potential, optimizing clinical study designs, supporting waivers for clinical studies, and informing drug label claims. Fedratinib dose should be reduced to 200 mg QD when a strong CYP3A4 inhibitor is co-administered and then re-escalated to 400 mg in a stepwise manner as tolerated after the strong CYP3A4 inhibitor is discontinued.
Phase-field modeling of fracture in heterogeneous materials: jump conditions, convergence and crack propagation
Authors: Hansen-Dörr Arne Claus , Brummund Jörg , Kästner Markus 
Published: September 2020

AbstractIn this contribution, a variational diffuse modeling framework for cracks in heterogeneous media is presented. A static order parameter smoothly bridges the discontinuity at material interfaces, while an evolving phase-field captures the regularized crack. The key novelty is the combination of a strain energy split with a partial rank-I relaxation in the vicinity of the diffuse interface. The former is necessary to account for physically meaningful crack kinematics like crack closure, the latter ensures the mechanical jump conditions throughout the diffuse region. The model is verified by a convergence study, where a circular bi-material disc with and without a crack is subjected to radial loads. For the uncracked case, analytical solutions are taken as reference. In a second step, the model is applied to crack propagation, where a meaningful influence on crack branching is observed, that underlines the necessity of a reasonable homogenization scheme. The presented model is particularly relevant for the combination of any variational strain energy split in the fracture phase-field model with a diffuse modeling approach for material heterogeneities.
CADbots: Algorithmic Aspects of Manipulating Programmable Matter with Finite Automata
Authors: Fekete Sándor P. , Gmyr Robert , Hugo Sabrina , Keldenich Phillip , Scheffer Christian , Schmidt Arne 
Published: September 2020

AbstractWe contribute results for a set of fundamental problems in the context of programmable matter by presenting algorithmic methods for evaluating and manipulating a collective of particles by a finite automaton that can neither store significant amounts of data, nor perform complex computations, and is limited to a handful of possible physical operations. We provide a toolbox for carrying out fundamental tasks on a given arrangement of particles, using the arrangement itself as a storage device, similar to a higher-dimensional Turing machine with geometric properties. Specific results include time- and space-efficient procedures for bounding, counting, copying, reflecting, rotating or scaling a complex given shape.
Comparison of Oropharyngeal Dysphagia in Brazilian Children with Prenatal Exposure to Zika Virus, With and Without Microcephaly
Authors: Oliveira Danielle Maria da Silva , Miranda-Filho Demócrito de Barros , Ximenes Ricardo Arraes de Alencar , Montarroyos Ulisses Ramos , Martelli Celina Maria Turchi , Brickley Elizabeth B. , Gouveia Mariana de Carvalho Leal , Ramos Regina Coeli , Rocha Maria Ângela Wanderley , Araujo Thalia Velho Barreto de , Eickmann Sophie Helena , Rodrigues Laura Cunha , Bernardes Jeyse Polliane de Oliveira Soares , Pinto Maria Helena Teixeira , Soares Karina Polo Norte Danda , Araújo Claudia Marina Tavares de , Militão-Albuquerque Maria de Fátima Pessoa , Santos Ana Célia Oliveira dos 
Published: September 2020

AbstractSevere brain damage associated with Zika-related microcephaly (ZRM) have been reported to result in oropharyngeal dysphagia (OPD); however, it is unknown if OPD presents in children with prenatal Zika virus (ZIKV) exposure but only mild or undetectable abnormalities. The aims of this study were: to compare the frequency and characteristics of OPD in children with ZRM and in children without microcephaly born to mothers who tested polymerase chain reaction positive (PCR+) for ZIKV during pregnancy; and to investigate the concordance of caregiver reports of OPD with the diagnosis from the clinical swallowing assessment (CSA). Between Mar/2017 and May/2018, we evaluated 116 children (n = 58 with microcephaly, n = 58 children without microcephaly born to ZIKV PCR + mothers) participating in the Microcephaly Epidemic Research Group (MERG) cohort of children born during the 2015–2016 ZIKV epidemic in Pernambuco, Brazil. To assess OPD we used: a CSA; a clinical assessment of the stomatognathic system; and a questionnaire administered to caregivers. The frequency of OPD was markedly higher in children with ZRM (79.3%) than in the exposed but normocephalic group (8.6%). The children with microcephaly also presented more frequently with anatomic and functional abnormalities in the stomatognathic system. There was a high degree of agreement between the caregiver reports of OPD and the CSA (κ = 0.92). In conclusion, our findings confirm that OPD is a feature of Congenital Zika Syndrome that primarily occurs in children with microcephaly and provide support for policies in which children are referred for rehabilitation with an OPD diagnosis based on caregiver report.
A note on Padé approximants of tensor logarithm with application to Hencky-type hyperelasticity
Authors: Rezaee-Hajidehi M. , Tůma K. , Stupkiewicz S. 
Published: September 2020

AbstractWe show that the logarithmic (Hencky) strain and its derivatives can be approximated, in a straightforward manner and with a high accuracy, using Padé approximants of the tensor (matrix) logarithm. Accuracy and computational efficiency of the Padé approximants are favourably compared to an alternative approximation method employing the truncated Taylor series. As an application, Hencky-type hyperelasticity models are considered, in which the elastic strain energy is expressed in terms of the Hencky strain, and of our particular interest is the anisotropic energy quadratic in the Hencky strain. Finite-element computations are carried out to examine performance of the Padé approximants of tensor logarithm in Hencky-type hyperelasticity problems. A discussion is also provided on computation of the stress tensor conjugate to the Hencky strain in a general anisotropic case.
Simulation of seismic ground motion fields via object-oriented spatial statistics with an application in Northern Italy
Authors: Menafoglio Alessandra , Sgobba Sara , Lanzano Giovanni , Pacor Francesca 
Published: September 2020

AbstractThis work offers a novel methodological framework to address the problem of generating data-driven earthquake shaking fields at different vibration periods, which are key to support decision making and civil protection planning. We propose to analyse the entire profiles of spectral accelerations and project their information content to unsampled locations in the system, based on the theory of Object Oriented Spatial Statistics. The proposed methodology combines a non-ergodic ground motion model with a fully functional model for the residual term, the latter consisting of (i) the spatially-varying systematic effects due to source, site and path, and (ii) the remaining aleatory error. The proposed methodology allows to generate multiple shaking scenarios conditioned on the data, jointly and consistently for all the vibration periods, overcoming the intrinsic limitations of existing multivariate approaches to the problem. The approach is tested on a vast dataset of ground motion records collected in the study-area of the Po Plain (Northern Italy), for which a region-specific fully non-ergodic GMM was previously calibrated. Our validation tests demonstrate the potentiality of the approach, which is capable to effectively simulate spectral acceleration profiles, while keeping the ability to capture the main physical features of ground motion patterns in the region.
An epidemiological modelling approach for COVID-19 via data assimilation
Authors: Nadler Philip , Wang Shuo , Arcucci Rossella , Yang Xian , Guo Yike 
Published: September 2020

AbstractThe global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation which incorporates new data in real-time through variational data assimilation. We analyze and discuss infection rates in the UK, US and Italy. We furthermore develop a custom compartmental SIR model fit to variables related to the available data of the pandemic, named SITR model, which allows for more granular inference on infection numbers. We compare and discuss model results which conducts updates as new observations become available. A hybrid data assimilation approach is applied to make results robust to initial conditions and measurement errors in the data. We use the model to conduct inference on infection numbers as well as parameters such as the disease transmissibility rate or the rate of recovery. The parameterisation of the model is parsimonious and extendable, allowing for the incorporation of additional data and parameters of interest. This allows for scalability and the extension of the model to other locations or the adaption of novel data sources.
Public expenditure spillovers: an explanation for heterogeneous tax reaction functions
Authors: Levaggi Rosella , Panteghini Paolo M. 
Published: September 2020

AbstractIn this article, we show that spillovers may provide an alternative explanation for the heterogeneity of tax reaction functions under tax competition. In particular, we assume the existence of$$n\ge 2$$n≥2jurisdictions, which compete to attract mobile capital in a context where public expenditure produces spillovers. We show that the latter can lead to asymmetric responses. For instance, jurisdictionimay react positively to a change in the tax rate of jurisdictionjand negatively to the change in jurisdictionz. From a policy point of view, these findings are helpful to understand the mixed results found by the empirical literature, and to analyse the tax reaction functions of city centres and suburban jurisdictions.