bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of a Prognostic Score for Recommended TACE Candidates with Hepatocellular Carcinoma Spontaneous Rupture
Authors: Zou Jixue , Yuan Jia , Zhou Xinghao , Xue Tongchun , Chen Rongxin , Zhang Lan , Ren Zhenggang 
Published: July 2020

Abstract
Background: Although transarterial chemoembolization（TACE）has been widely used for spontaneously ruptured hepatocellular carcinoma (HCC), no existing models can be used for survival prediction. Thus, the aim of the present study was to develop and validate a nomogram for risk prediction of HCC rupture after TACE treatment.Methods: The medical records of patients who underwent transarterial chemoembolization therapy from January 2015 to April 2019 at our Hospital were retrospectively screened. HCC was diagnosed by either imaging or histological evaluation according to the AASLD guideline. Factors that were found to be significant in univariate analysis were subjected to multivariate analysis. Factors in the nomogram were identified by multivariate Cox hazard analysis. The concordance index was calculated. Results: This study consisted of 55 patients with spontaneously ruptured HCC receiving TACE at our center from January 2015 to April 2019. The median overall survival was 6.4 months, with 0.5-year and 1-year survival being 52.7% and 41.8%, respectively. In univariate analysis, largest tumor size, total bilirubin level, and aspartate aminotransferase level were associated with overall survival. Multivariate analysis suggested that total bilirubin level and the max diameter of the tumors were independent prognostic factors to predict overall survival. Based on these variables, we developed and validated a nomogram for individual patient risk stratification of HCC rupture after TACE treatment. The concordance index for overall survival prediction was 0.748 (95% CI: 0.691-0.805).Conclusions: Based on the nomogram, we have provided an intuitive tool for estimating the prediction of ruptured HCC patients. This study may help to improve the perioperative strategy and treatment outcome.
Evaluating the Impact of Biannual School-Based and Community-Wide Treatment on Urogenital Schistosomiasis in Niger
Authors: Phillips Anna Elizabeth , Tohon Zilahatou , Dhanani Neerav A. , Sofo Boubacar , Gnandou Issa , Sidikou Boubacar , Noma Adamou Garba , Madougou Bassirou , Alto Oumarou , Sebangou Hannatou , Halilou Kader M. , Andia Roumanatou , Garba Amadou , Fenwick Alan , Hamidou Amina A. 
Published: July 2020

Abstract
Background The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) coordinated a five-year study implemented in several countries, including Niger, to provide an evidence-base for programmatic decisions regarding cost-effective approaches to preventive chemotherapy for schistosomiasis control. Methods This was a cluster-randomised trial investigating six possible combinations of annual or biannual community-wide treatment (CWT), school-based treatment (SBT), and holidays from mass treatment over four years. The most intense arm involved two years of annual CWT followed by two years of biannual CWT, while the least intensive arm involved one year of annual SBT followed by a year without treatment and two more years of annual SBT. The primary outcome of interest was prevalence and intensity of S. haematobium among 100 children aged 9-to-12-years sampled each year. In addition, 100 children aged 5-to-8 years in their first year of school and 50 adults (aged 20-to-55 years) were tested in the first and final fifth year of the study. Results In total, data was collected from 167,500 individuals across 225 villages in nine districts within the Niger River valley, Western Niger. Overall, prevalence of S. haematobium decreased from baseline to Year 5 across all study arms. The relative reduction of prevalence was greater in biannual compared with annual treatment across all arms, however, the only significant difference was seen in areas with a high starting prevalence. Although adults were not targeted for treatment in SBT arms, a statistically significant decrease in prevalence among adults was seen in moderate prevalence areas receiving biannual (10.7% to 4.8%) SBT (p<0.001). Adults tested in the annual SBT group also showed a decrease in prevalence between Year 1 and Year 5 (12.2% to 11.0%), but this difference was not significant.Conclusions These findings are an important consideration for schistosomiasis control programs that are considering elimination and support the idea that scaling up the frequency of treatment rounds, particularly in areas of low prevalence, will not eliminate schistosomiasis. Interestingly, the finding that prevalence decreased among adults in SBT arms suggests that transmission in the community can be reduced, even where only school children are being treated, which could have logistical and cost-saving implications for the national control programmes.
Who Indicates Caesarean Section in Romania? A Cross-Sectional Survey in Tertiary Level Maternity on Childbirth Patients and Doctors' Profiles
Authors: Simionescu Anca Angela , Horobet Alexandra , Marin Erika , Belascu Lucian 
Published: July 2020

Abstract
Background. C-section rate in Romania is the second-highest in the European Union (44.1% in 2017) and the number of C-sections performed in the country increased by 32.1% between 2009 and 2017. We offer for the first time insights into the practice and perceptions of patients and doctors in Romania towards delivery mode and on health system particularities that lead to increased numbers of C-sections. The objectives are 1) to compare the preferred modes of birth among women 2) to draw a profile of patients in whose case the actual birth method is different from the preferred method, and 3) to outline a profile of doctors and patients based on the modes of delivery. Methods. We conduct a statistical analysis based on an observational, analytical, and cross-sectional survey on 117 singleton pregnant women more than 36 weeks in spontaneous labor in tertiary level maternity in Romania. Various statistical tests have been used to indicate statistical significance. Results. Our results show an increase of almost 58% in actual childbirth mode against preferred childbirth by C-sections, rather difficult to justify based only on medical emergencies. There are 22 patients with non-concordant C-section indications between preferred and actual mode of birth, 7 of them (31.8%) preferred natural birth and 15 (68.2%) preferred C-section. Scarred uterus is the most frequent medical indication for C-section (30.7%). Overall, birth and birth pain assessment correlates to preferred and actual delivery modes, but respondents distinguish clearly between birth pain alone and their overall birth experience. The profiles of patients with concordant and non-concordant delivery modes are different, and indicate a statistically significant difference between the preference for delivery and actual birth method. Patients who preferred vaginal birth, but gave birth by C-section, are mature and more educated women, in the middle to the high-income category, mostly attended by consultant doctors and specialists. Doctors’ profiles show that specialists and consultants attend the largest share of non-concordant births, while residents and young senior doctors attend mostly vaginal births. Conclusions. We emphasize health system particularities in Romania as triggers of high C-section rates that favor womens’ preferences against C-section medical indication.
On the crystal chemistry of sulfur-rich lazurite, ideally Na7Ca(Al6Si6O24)(SO4)(S3)–·nH2O
Authors: Sapozhnikov Anatoly N. , Tauson Vladimir L. , Lipko Sergey V. , Shendrik Roman Yu. , Levitskii Valery I. , Suvorova Lyudmila F. , Chukanov Nikita V. , Vigasina Marina F. 
Published: July 2020

AbstractDark blue lazurite from the Malo-Bystrinskoe lazurite deposit, Baikal Lake area, Eastern Siberian region, Russia, was analyzed by electron microprobe and revealed an unusually high content of total sulfur corresponding to 8.3 wt% S. The relative content of sulfur in sulfate and sulfur in sulfide form was determined by wet chemical analysis. The H2O content was measured by means of differential thermal analysis in combination with mass spectrometry and infrared (IR) spectroscopy. The charge-balanced empirical formula of lazurite calculated on the basis of 12 (Al+Si) atoms per formula unit was (Na6.97Ca0.88K0.10)Σ7.96[(Al5.96Si6.04)Σ12O24](SO4)1.092−(S3−)0.55S0.052− Cl0.04·0.72H2O. The presence of H2O molecules and (S3)– and (SO4)2– groups was confirmed by the combination of IR, Raman, electron paramagnetic resonance (EPR), and X-ray photoelectron spectroscopy (XPS) methods. The idealized formula of lazurite is Na7Ca[Al6Si6O24](SO4)2–(S3)–·H2O, and it is believed that extra-framework cations and anions are grouped into clusters of [Na3Ca·SO4]3+ and [Na4(S3)–]3+. The types of isomorphous substitutions in nosean and haüyne are discussed. Lazurite is a clathrate-type mineral, which may be an effective (S3)– sensor due to the stability of the trisulfur radical anion in isolated cages of the crystal structure. This specific feature makes it possible to study the behavior of this ubiquitous radical anion over larger T and P ranges as compared to free species. This kind of lazurite, with oxidized and reduced sulfur species, seems to be appropriate for the estimation of the fugacity of SO2 and O2 in metasomatic systems forming lazurite-containing rocks. The systematic presence of incommensurate modulations is a unique structural feature of Baikal lazurite and may be an important marker indicating provenance of the mineral.
New Mineral Names*,†
Authors: Belakovskiy Dmitriy I. , Cámara , Fernando , Uvarova Yulia 
Published: July 2020

In this issue
This New Mineral Names has entries for 21 new minerals, including alexkhomyakovite, andreadiniite, arsenmedaite, barwoodite, bodieite, ciriottiite, clino-oscarkempffite, ferrovorontsovite, ilirneyite, kannanite, magnesiohornblende, merelaniite, oyonite, pararaisaite, petříčekite, quijarroite, staročeskéite, tantalowodginite, topsøeite, tsygankoite, and vorontsovite.
Early warning of debris flow using optimized self-organizing feature mapping network
Authors: Wang Xuedong , Wang Cui , Zhang Chaobiao 
Published: July 2020

Abstract
Early warning of debris flow is one of the core contents of disaster prevention and mitigation work for debris flow disasters. There are few early warning methods based on the combination of rainfall threshold and geological environment conditions. In this paper, we presented an early warning method for debris flow based on the infinite irrelevance method (IIM) and self-organizing feature mapping (SOFM), and applied it to Liaoning Province, China. The proposed model consisted of three stages. Firstly, eight geological environmental conditions and two rainfall-inducing conditions were selected by analyzing the factors affecting the development of debris flow in the study area, and the rainfall threshold for debris flow outbreak was 150 mm. Secondly, the correlation between various factors was analyzed by IIM, which prevented the blindness of parameter selection and improved the prediction accuracy of the model. Finally, SOFM was employed to predict the test data. Experimental results showed that the IIM-SOFM model had a strong early warning ability. When 25 samples of low-frequency debris flow area were selected, the accuracy rate of the IIM-SOFM model with optimized network structure parameters was 100%, which it was obviously superior to the rainfall threshold method, BP neural network and competitive neural network. Consequently, it is feasible to use the IIM-SOFM model for early warning of debris flow, outperforming traditional machine learning methods.
Storage Conditions of Immunobiologicals and their Influence on the Efficacy and Safety in the Treatment of Autoimmune Rheumatic Diseases
Authors: de Assis Damasce Tássia Moraes , Fernand Vander , Leite da Silva Cristhiane Almeida , Candido da Silva Ageo Mario , Ishikawa Cezar Santo Luciana Carolina , Palmiro da Silva e Lima Veronica 
Published: July 2020

Objective:
The study aimed to evaluate the influence of storage temperature on immunobiological efficacy and safety in autoimmune rheumatic disease treatment.

Methods:
This observational study included adult patients with autoimmune rheumatic diseases who used immunobiologicals stored at home and were followed up at the rheumatology outpatient clinic of the General University Hospital of Cuiabá, Mato Grosso, Brazil, in 2017/2018. Patients were evaluated regarding disease activity and occurrence of adverse events, and a household survey of the temperature of the storage environment of these drugs was conducted.

Results:
Sixty patients with a mean age of 50.4 years were evaluated. Of these, 39 patients (65%) stored their biological drugs outside the recommended temperature range. Storage of the immunobiological at the incorrect temperature was 76% higher among patients with moderate/high rheumatic disease activity (p=0.003).

Conclusion:
Most patients stored their immunobiologicals outside the temperature range recommended in the package insert, and there was an association between incorrect storage temperature and moderate/high autoimmune rheumatic disease activity.
Management of Market Surveillance Authorities for Construction Products
Authors: Kouros Kyriacos I. , Chrysostomou Christis Z. 
Published: July 2020

Background:
The Construction Products Regulation (CPR) entered into full force in the European Union (EU) on 1 July 2013 aiming to improve the free movement of construction products. Several EU Commission Reports acknowledge as one of the main shortcomings, the less than active role of Member States in market surveillance and suggest examining and implementing methods for more efficient prioritisation and organisation of market surveillance activities.

Objective:
The purpose of the paper is to investigate management elements of the Market Surveillance Authorities (MSAs) for construction products in the EU. To this end, and to collect information on the current level of effectiveness of the organisational approach of the MSAs, it is imperative to collect information on the main relevant management activities of the MSAs, i.e. strategic analysis, risk assessment and performance measurement.

Methods:
The paper presents background information on the level of market surveillance in the EU. In order to provide further insight, a survey was carried out to collect information and views from representatives of the Member States’ MSAs of construction products participating in the EU committee “Administrative Cooperation Group for the Construction Products Regulation” (AdCo-CPR).

Results:
Through the findings of investigating management perspectives of the MSAs, it can be concluded that currently, market surveillance of construction products in the Member States markets is limited, and MSAs should consider implementing a quality management system to improve the effectiveness of market surveillance activities as well as to create public value.

Conclusion:
The findings also suggest that further investigation is needed to be related to strategy, risk and performance management of the MSAs in order to enhance performance and effectiveness.
PENGEMBANGAN BAHAN AJAR E-BOOK PRAKTIKUM AKUNTANSI PERUSAHAAN DAGANG BERBASIS SCIENTIFIC APPROACH SEBAGAI SUMBER BELAJAR ALTERNATIF
Authors: Kirana Rizka Wahyu candra 
Published: July 2020

Pembelajaran yang efektif dan efisien dapat diwujudkan dengan adanya ketersediaan bahan ajar penunjang yang menyokong serta memadai. E-book merupakan bahan ajar inovatif berbentuk digital sebagai bentuk pembaharuan pemanfaatan hasil teknologi yang berguna dalam proses pembelajaran. Penelitian ini bertujuan mengembangkan bahan ajar e-book pada mata pelajaran praktikum akuntansi perusahaan dagang berbasis scientific approach. Tujuan penelitian yaitu menganalisis e-book yang dikembangkan dan menganalisis tingkat kelayakan e-book. Model pengembangan dalam penelitian ini menggunakan model pengembangan four-D dari Thiagajaran, Semmel dan Semmel mulai dari langkah pendefinisian sampai langkah pengembangan. Hasil penelitian menunjukan hasil rata-rata kelayakan yang diperoleh dari validator ahli bidang sebesar 85,6% dengan kriteria “sangat layak”. Komponen validator bidang materi mendapatkan hasil sebesar 85,9% dengan kriteria sangat layak, komponen validator bidang Bahasa mendapatkan hasil sebesar 83,7% dengan kriteria sangat layak dan komponen validator bidang grafis mendapatkan hasil sebesar 87,3% dengan kriteria sangat layak. Data tersebut diperoleh dari lembar validasi ahli bidang yang berisi kriteria penilaian menggunakan skala likert melalui angket tertutup, hasilnya diolah dan diinterprestasikan sesuai kriteria tingkat kelayakan e-book. Kesimpulan penelitian ini e-book praktikum akuntansi perusahaan dagang berbasic scientific approach “sangat layak” dimanfaatkan dalem proces pembelajaran sebagai sumber belajar alternatif.
Tobacco-Free Policy Support among Students in University Campuses
Authors: Yasin Siti Munira , Zubillah Aisyah , Selamat Mohamad Ikhsan , Ismail Nurhuda 
Published: July 2020

The purpose of this study was to determine support for various tobacco-free policies among students in public universities. This cross-sectional study was conducted among 406 students from three main campuses of a university in July 2018. Three hundred ninety-two students responded from three campuses in Selangor. There was a significant association between knowledge of secondhand smoke (SHS) and the types of tobacco-free policies. Students who perceived knowing the dangers of SHS also supported smoke-free cars and campus policy. In conclusion, knowledge of secondhand smoke, third-hand smoke, and tobacco-free policies should be enhanced.
Keywords: Tobacco-free campus, Second-hand smoker, students.
eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer-review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v5i14.2246
PENANAMAN RASA TABU KORUPSI PADA ANAK SEKOLAH DASAR
Authors: Malih Sa'i 
Published: July 2020

ASTRAK
Korupsi di Indonesia sudah menjadi penyakit yang menahun. Aceh adalah provinsi terkorup ke dua di Indonesia. Pengobatan penyakit korupsi itu telah dilakukan dengan berbagai cara, namun nampaknya semua gagal. Satu cara yang diharapkan dapat mencegah korupsi di masa yang akan datang adalah dengan membina mental anak didik, yaitu menanamkan rasa tabu melakukan korupsi. Ini perlu dilakukan karena penanaman rasa tabu ketika masih kecil, akan mewarnai kehidupan hingga ke usia tua. Peraturan Perundang-Undangan yang memerintahkan ke arah itu sudah ada. Akan tetapi setelah diadakan penelitian, ternyata peraturan itu belun dilaksanakan secara terprogram. Alasan tenaga pendidik belum melaksanakan itu karena belum ada petunjuk teknis dan petunjuk pelaksana yang dibuat secara rinci, baik dalam kurikulum atau silabus nasional maupun kurikulum atau silabus local. Supaya itu cepat terwujud, maka hendaknya Pemerintah Daerah, Majelis Pendidikan Daerah, dan lembaga lain yang memegang kebijakan di bidang pendidikan harus segera membuat regulasi baru di bidang ini.

Kata Kunci: Pendidikan, Anak didik, Tabu, Korupsi
PERTUMBUHAN KEGIATAN KEWIRAUSAHAAN DISEKITARAN KAMPUS UIN AR-RANIRY, BANDA ACEH
Authors: Murdani Teuku 
Published: July 2020

ABSTRAK
Kampus spemacam UIN Ar-Raniry Banda Aceh merupakan tempat dimana ramai orang yang datang untuk belajar. Mereka datang dari berbagai kabupaten/kota di Aceh bahkan ada dari provinsi lain di Indonesia. Mereka datang ke Banda Aceh membawa resourch untuk dihabiskan seperti uang kuliah, uang untuk membeli buku, makanan, sewa kost, hiburan dan lain sebagainya. Seorang wirausahawan akan melihat ini sebagai sebuah kesempatan dan akan menciptakan alat untuk medapatkan kesempatan tyersebut. Kenyataannya, banyak aktifitas wirausaha disekitar kampus saat ini, khususnya usaha penjualan makanan untuk mahasiswa. Penelitian ini bertujuan untuk melihat motivasi dibalik kegiatan kewirausahaan tersebut dan apa strategi pemasaran yang mereka praktekkan. Untuk mengumpulkan data saya memakai metode kualitatif dengan tehnik observasi dan wawancara. Ranai dari wirausahawan menyebutkan bahwa ide berwirausaha karena mereka ingin memiliki bisnis sendiri ikut teman, karena ramai yang datang ke kampus setiap hari maka kebanyakan dari usaha tergolong sukses. Tidak ada strategi khusus tetapi ada yang menggunakan media sosial.
The Affordable Care Act: Effects of Insurance on Diabetes Biomarkers
Authors: Marino Miguel , Angier Heather , Springer Rachel , Valenzuela Steele , Hoopes Megan , O’Malley Jean , Suchocki Andrew , Heintzman John , DeVoe Jennifer , Huguet Nathalie 
Published: July 2020

OBJECTIVE
We sought to understand how Affordable Care Act (ACA) Medicaid expansion insurance coverage gains are associated with changes in diabetes-related biomarkers.

RESEARCH DESIGN AND METHODS
This was a retrospective observational cohort study using electronic health record data from 178 community health centers (CHCs) in the ADVANCE (Accelerating Data Value Across a National Community Health Center Network) network. We assessed changes in diabetes-related biomarkers among adult patients with diabetes in 10 Medicaid expansion states (n = 25,279), comparing newly insured with continuously insured, discontinuously insured, and continuously uninsured patients pre– to post–ACA expansion. Primary outcomes included changes from 24 months pre- to 24 months post-ACA in glycosylated hemoglobin (HbA1c), systolic (SBP) and diastolic (DBP) blood pressure, and LDL cholesterol levels.

RESULTS
Newly insured patients exhibited a reduction in adjusted mean HbA1c levels (8.24% [67 mmol/mol] to 8.17% [66 mmol/mol]), which was significantly different from continuously uninsured patients, whose HbA1c levels increased (8.12% [65 mmol/mol] to 8.29% [67 mmol/mol]; difference-in-differences [DID] −0.24%; P &lt; 0.001). Newly insured patients showed greater reductions than continuously uninsured patients in adjusted mean SBP (DID −1.8 mmHg; P &lt; 0.001), DBP (DID −1.0 mmHg; P &lt; 0.001), and LDL (DID −3.3 mg/dL; P &lt; 0.001). Among patients with elevated HbA1c in the 3 months prior to expansion, newly insured patients were more likely than continuously uninsured patients to have a controlled HbA1c measurement by 24 months post-ACA (hazard ratio 1.25; 95% CI 1.02–1.54].

CONCLUSIONS
Post-ACA, newly insured patients had greater improvements in diabetes-related biomarkers than continuously uninsured, discontinuously insured, or continuously insured patients. Findings suggest that health insurance gain via ACA facilitates access to appropriate diabetes care, leading to improvements in diabetes-related biomarkers.