bluuebunny/crossref_metadata_2025_split huggingface dataset:
CAWA LAMPUNG : KAMUS BAHASA INDONESIA-LAMPUNG DIALEK A BERBASIS ANDROID
Authors: Febriansyah Febi Eka , Ardiansyah Ardiansyah , Darmaji Afan 
Published: January 2021

<p><em>Indonesia is country rich in cultural diversity, one of which is regional languages. In the Law of the Republic of Indonesia Number 24 of 2009 article 1 paragraph 6, what is meant by regional languages is the language used for generations by Indonesian citizens in regional areas in the territory of the Unitary State of the Republic of Indonesia. There are many regional languages in Indonesia, one of which is Lampung. however, the reduction in Lampung language speakers can cause the Lampung language to disappear. With the help of technology, especially Android, it can help to increase interest in Lampung language, especially in Lampung adolescents. this research will develop an Indonesian translator application to the Lampung dialect A on the Android Platform. The application is named Cawa Lampung. the translation process is carried out by the system with word translation. Every word is carried out the stemming process using the Nazief Adriani stemming method. The system development method used is eXtreme Programming. From the functional test results, all functions went well, and from the nonfunctional results it has a value of 85.57% which means "very good".</em></p><p><strong><em>Keywords</em></strong><em>: Android, T</em><em>ranslate</em><em>, Lampung</em><em> language</em><em>, Stemming Nazief Adriani</em><em> </em><em>Algorit</em><em>h</em><em>m</em></p><p><em>Indonesia adalah negara yang kaya akan keragaman budaya, salah satunya adalah bahasa daerah. Dalam Undang-Undang Republik Indonesia Nomor 24 tahun 2009 pasal 1 ayat ke 6, yang dimaksud bahasa daerah adalah bahasa yang digunakan secara turun-temurun oleh warga negara Indonesia di daerah daerah di wilayah Negara Kesatuan Republik Indonesia. Ada banyak bahasa daerah di Indonesia, salah satunya adalah bahasa lampung. namun berkurangnya penutur bahasa lampung dapat mengakibatkan bahasa daerah lampung akan hilang. Dengan bantuan teknologi terutama Android, dapat membantu meningkatkan lagi minat berbahasa lampung terutama pada remaja lampung. penelitian ini akan mengembangkan aplikasi translator bahasa Indonesia ke Bahasa Lampung dialek A pada Platform Android. Aplikasi diberi nama Cawa Lampung. proses terjemahan dilakukan oleh sistem dengan terjemahan kata perkata. Setiap kata dilakukan proses stemming dengan mengunakan metode stemming Nazief Adriani. Metode pengembangan sistem yang digunakan yaitu eXtreme Programming. Dari hasil pengujian fungsional semua fungsi berjalan dengan baik, dan dari hasil non fungsional memiliki nilai 85.57 % yang memiliki makna “sangat baik”..</em></p><p><strong><em>Kata kunci</em></strong><em>: Android, Terjemahan, Bahasa Lampung, Algoritma Stemming Nazief Adriani</em></p>
Rancang Bangun Media Pembelajaran Pengenalan Kombinasi Warna Berbasis Mikrokontroler dengan Visualisasi Desktop
Authors: Nugraha Muhammad Yasir Bintang , Susanto Rudi , Pradana Afu Ichsan 
Published: January 2021

<p class="AbstractEnglish"><strong>Abstract:</strong> The purpose of this study was to create a learning media for color combination recognition that serves to help introduce colors and color combinations to the students of Al-Amin 3 Cemani Kindergarten. The stages of developing this color combination application consist of analysis, design, manufacture and testing. This learning media work system uses the Arduino Uno R3 (ATMEGA328) as a data processing center, TCS230 sensors as data input media. The data from Arduino Uno R3 processing results is displayed via RGB LED and a Visual Basic 2012-based desktop application. In the desktop application, the data input for color 1 and color 2 is processed through the combination button found in the application to combine color 1 and color 2. Overall test results, media learning color recognition and color combinations can work well in combining colors according to Munsell's Color Theory.</p><p class="AbstrakIndonesia"><strong>Abstrak: </strong>Tujuan penelitian ini adalah untuk membuat suatu media pembelajaran pengenalan kombinasi warna yang berfungsi untuk membantu mengenalkan tentang warna dan kombinasi warna pada siswa TK Al-Amin 3 Cemani. Tahapan pengembangan aplikasi kombinasi warna ini terdiri dari analisis, perancangan, pembuatan dan pengujian Sistem kerja media pembelajaran ini menggunakan Arduino Uno R3 (ATMEGA328) sebagai pusat pengolahan data, sensor TCS230 sebagai media input datanya. Data hasil pemrosesan Arduino Uno R3 ditampilkan melalui RGB LED dan aplikasi desktop berbasis Visual Basic 2012. Pada aplikasi desktop data input warna 1 dan warna 2 diolah melalui tombol kombinasi yang terdapat pada aplikasi untuk mengkombinasikan warna 1 dan warna 2. Hasil pengujian secara keseluruhan, media pembelajaran pengenalan warna dan kombinasi warna sudah dapat bekerja dengan baik dalam mengkombinasikan warna sesuai dengan Teori Warna Munsell</p>
Analysis of Financial Ratio That Affecting Total Financing of Bank Umum Syariah In Indonesia
Authors: Ulfa Zerlinda Tharifah , Purwanto Purwanto 
Published: January 2021

<p><em>This study aimed to analyze the factors that influence the Total Financing of Bank Umum Syariah (BUS) in Indonesia. Islamic banking system in Indonesia was developed within the framework of the dual banking system to give alternatives for more complete banking services to the people of Indonesia. Islamic banking in Indonesia has grown rapidly every year, but it can not be denied the role of Islamic banking in the economy is still relatively small compared with conventional banking. The amount of total financing is only about 5,56% of the banking total credit. It can be seen also in the proportion of assets Islamic banking to national banking assets that only 4.8% and 18.75% of the total national banking accounts. The research data is taken from the financial reports of 10 of Islamic banks in Indonesia. The method used is a quantitative method and </em><em>multiple regression analysis, </em><em>proceed using </em><em>SPSS to </em><em>test normality, </em><em>multicollinearity, </em><em>heteroscedasticity</em><em> and </em><em>autocorrelation</em><em>. </em><em>The result of this research showed that the Capital Adequacy </em><em>r</em><em>atio(CAR), Non-Performing Financing (NPF), and Operating Expense Operating Income ratio (OEOI) had a significant effect on total financing. Meanwhile, Return on Asset (ROA) and Financing to Deposit Ratio (FDR) had no significant effect on the total financing of Bank Umum Syariah.</em><em> Adjusted R Square value is 0.239 or 23,9%. This value shows that the percentage of the contribution of independent variables on total financing is 23.9 %. The remaining percentages are due to other variables excluded in this model.</em></p>
Feeder-free differentiation and expansion for T cells from induced pluripotent stem cells
Authors: Iriguchi Shoichi , Yasui Yutaka , Kawai Yohei , Arima Suguru , Kunitomo Mihoko , Sato Takayuki , Ueda Tatsuki , Minagawa Atsutaka , Mishima Yuta , Yanagawa Nariaki , Baba Yuji , Miyake Yasuyuki , Nakayama Kazuhide , Takiguchi Maiko , Shinohara Tokuyuki , Nakatsura Tetsuya , Yasukawa Masaki , Kassai Yoshiaki , Hayashi Akira , Kaneko Shin 
Published: January 2021

Abstract
Clinical efficacy demonstrated by chimeric antigen receptor T cell therapy call for further development that could broaden their applicability. One such direction is to develop alternate T-cell sources and T cells differentiated from pluripotent stem cells may be an ideal candidate.The present protocol provides a feeder-free and scalable method to generate T lymphocytes from induced pluripotent stem cells.
Descending neocortical output critical for skilled forelimb movements is distributed across projection cell classes
Authors: Park Junchol , Phillips James , Martin Kathleen , Hantman Adam , Dudman Joshua 
Published: January 2021

Abstract
Motor cortex is a key node in the forebrain circuits that enable flexible control of limb movements. The influence of motor cortex on movement execution is primarily carried by either pyramidal tract neurons (PT), which project directly to the brainstem and spinal cord, or intratelencephalic neurons (IT), which project within the forebrain. The logic of the interplay between these cell types and their relative contribution to the coordination and scaling of forelimb movements remains unclear. Here we combine large-scale neural recordings across all layers of motor cortex with cell-type specific perturbations in a cortex-dependent mouse behavior: kinematically-variable manipulation of a joystick. Our data demonstrate that descending neocortical motor commands are distributed across projection cell classes. IT neuron activity, in comparison to PT neurons, carries a larger fraction of information about gross movement kinematics. We find that forelimb movements are robust to optogenetic silencing of PT output, but substantially impaired by silencing Layer 5a IT projection neurons. Dorsal striatum is the unique extracortical integration point for IT and PT output pathways and its activity was more dependent upon IT input than PT input during movement execution. These data indicate that forebrain extrapyramidal pathways can be critical for regulating kinematics of motor skills.
Detection of Shallow Anterior Chamber Depth from Two-dimensional Anterior Segment Photographs using Deep Learning
Authors: Qian Zhuyun , Xie Xiaolin , Yang Jianlong , Ye Hongfei , Wang Zhilei , Chen Jili , Liu Hui , Liang Jianheng , Jiang Lihong , Zheng Ce , Chen Xu 
Published: January 2021

Abstract
Background: The purpose of this study was to implement and evaluate a deep learning (DL) approach for automatically detecting shallow anterior chamber depth (ACD) from two-dimensional (2D) overview anterior segment photographs.Methods: We trained a DL model using a dataset of anterior segment photographs collected from Shanghai Aier Eye Hospital from June 2018 to December 2019. A Pentacam HR system was used to capture a 2D overview eye image and measure the ACD. Shallow ACD was defined as ACD less than 2.4 mm. The DL model was evaluated by a five-fold cross-validation test in a hold-out testing dataset. We also evaluated the DL model by testing it against two glaucoma specialists. The performance of the DL model was calculated by metrics, including accuracy, sensitivity, specificity, and area under the receiver operating characteristic curve (AUC).Results: A total of 4,322 photographs (2,054 shallow AC and 2,268 deep AC images) were assigned to the training dataset, and 482 photographs (229 shallow AC and 253 deep AC images) were held out for internal testing dataset. In detecting shallow ACD in the internal hold-out testing dataset, the DL model achieved an AUC of 0.91 (95% CI, 0.88–0.94) with 82% sensitivity and 84% specificity. In the same testing dataset, the DL model also achieved better performance than the two glaucoma specialists (accuracy of 80% vs. accuracy of 74% and 69%).Conclusions: We proposed a high-performing DL model to automatically detect shallow ACD from overview anterior segment photographs. Our DL model has potential applications in detecting and monitoring shallow ACD in the real world. Trial registration：http://clinicaltrials.gov, NCT04340635, retrospectively registered on 29 March 2020.
A cross sectional survey of personal hygiene positive behaviour related to COVID-19 prevention and control among Indonesian communities
Authors: Lestari Fatma , Kadir Abdul , Idham Muhammad , Azwar Fahrul , Ramadhany Ganis , Sembiring Fredy , Ghazmahadi Ghazmahadi , Hakim Abdul , Modjo Robiana , Widanarko Baiduri , Kusminanti Yuni 
Published: January 2021

Abstract
Background: The trend of COVID-19 confirmed cases has continually risen in Indonesia, this pandemic situation has affected several life sectors, including health sectors, education, economic, services, and employment sectors. Public health and social measures as recommended by Word Health Organization are required to be implemented in order to prevent the coronavirus disease spread. People’s behaviours can also affect the spread of the COVID-19 virus. Public behaviours including proper personal hygiene and healthy life practices, the use of appropriate masks, and the application of good disinfectants have an important role in human’s health and protection towards prevention and control of COVID-19 spreads. This study aims to perform a survey of public behaviour and best practices related to COVID-19 prevention and control among Indonesian communities. Methods: A cross-sectional study was designed to collect information related to public behaviour related to COVID-19 prevention and control using an online survey. Respondents were gathered from 34 provinces in Indonesia through the Indonesia National Safety and Health Council network and Universities network. Respondents voluntarily submitted their response to a pre-designed online questionnaire. The collected data was then analyzed using SPSS 24.0. Results: A total of respondents 771 subjects (male 386; female 385) were submitted their response. The results show that 96% of participants implementing positive behaviour of personal hygiene including wearing a mask when going outside their house and almost 67.3% of respondents sprayed a disinfectant in their house. The majority of participants hold a door handle (37.2%) and desk (28.1%) at frequency of more than six times a day. There were 8.2% of participants implementing good personal hygiene including hand washing at least once a day and maximum of more than six times after going to the toilet. At risk behaviour were conducted by respondents at which they touched part of their face at frequency once during an hour. It has been identified that male are less likely to perform better hand hygiene as opposed to female. In conclusion, study showed that positive behaviour of personal hygiene related to COVID-19 has been implemented among Indonesian communities. This result suggested that positive behaviour based on community based prevention and control need to be continually maintain in order to prevent and control COVID-19 spreads.
Assimilation of Digital Health by Family Physicians in Canada
Authors: Paré Guy , Pomey Marie-Pascale , Raymond Louis , Badr Janine 
Published: January 2021

Abstract
Background: In recent years, governments, medical associations and other health care stakeholders have advocated digital health as a promising avenue to reduce inefficiencies, improve the delivery of health care services, increase the quality of primary care, and detect and manage infectious diseases. The present study aims to investigate the assimilation of digital health by family physicians, going beyond the simple adoption of these technologies to further understand the breadth and depth of their use in clinical practice for the diagnosis, treatment and prevention of disease, and for the monitoring of chronically-ill patients.Methods: The study was designed as an online survey. After conducting a pre-test of the questionnaire instrument, an invitation to participate in the study was sent to 7,664 members of the Quebec Federation of General Practitioners. The online questionnaire was developed on the Qualtrics survey platform. Data was collected from 768 family physicians, representing a 10% response rate.Results: Findings show that a large majority of the sampled physicians have yet to assimilate digital health within their medical practice. This is true in terms of both the physicians not incorporating digital health technologies into their routine work patterns and their not using these technologies to their full potential. The minority of respondents who showed a somewhat higher level of assimilation were motivated by patients’ greater requests related to digital health (e.g. for online consultations) and a greater chronic care caseload, and are characterized by their greater need for digital health training and their younger age, and use an EMR system that includes more functionalities (e.g. pharmaceutical advisers/prescribers).Conclusions: This study has policy implications in terms of the need for greater motivation and training of family physicians in order for them to make more extensive and innovative use of digital health technologies in their medical practice, for greater interoperability and integration of the digital health tools made available to them, and for greater awareness of their patients’ emerging attitudes and behaviors with regards to digital health. These implications make even more sense in the context of the current Covid-19 pandemic.
Genome-wide Identification and Expression Analysis of the 14-3-3 Gene Family in Cotton (Gossypium Hirsutum L.)
Authors: gao wenju , chen qin , zhao jieyin , wang peng , li duolu , zheng kai , long yilei , jiao yang , wang yuxiang , geng shiwei , su xuening , qu yanying , chen quanjia 
Published: January 2021

Abstract
Background: As a ubiquitous acid-regulating protein family in eukaryotes, 14-3-3 proteins are widely involved in the growth and development of plants. With the development of the third-generation sequencing technology and the smooth completion of the cotton genome work, it is possible to explore the existence and distribution of the 14-3-3 protein family in cotton.Results: In this paper, 33, 33, 17 and 18 members were identified from this family in Gossypium hirsutum((AD)1), G. barbadense((AD)2), G. arboreum(A2) and G. raimondii(D5), respectively. In particular, evolution analysis, structure analysis and functional expression analysis of this protein family in G. hirsutum((AD)1) were carried out. The results showed that compared with Arabidopsis and rice, the phylogenetic tree and gene structure clearly divided the 14-3-3 protein family into two subgroups in G. hirsutum((AD)1), the ε group and the non-ε group; Analysis of transcriptome expression patterns revealed that this family was significantly induced to express under abiotic stress; Most 14-3-3 proteins have a large number of cis-acting elements related to growth, development and abiotic stress in the promoter region, among which elements related to drought stress account for the largest proportion; The results of qRT-PCR showed that the expression of 14-3-3 protein had significant differences under drought stress.Conclusions: In summary, this study signified that the 14-3-3 protein family is relatively conserved in the evolutionary expansion of cotton, and may be involved in the growth and development of plants and the mechanism of stress resistance. These results provide an important theoretical and experimental basis for further analysis and verification of the function of 14-3-3 protein in cotton.
The Expression of Type II TA System Genes Following Persister Cell Formation in Pseudomonas Aeruginosa Isolates in The Exponential and Stationary Phases
Authors: Zadeh Rezvan Golmorazi , Mirshekar Maryam , Kalani Behrouz Sadeghi , Masjedian Faramarz , Barati Mahmood 
Published: January 2021

Abstract
Objectives: Failure of infection therapy in the presence of antibiotics has become a major problem which has been mostly attributed to the ability of bacterial persister cell formation. Bacteria use various mechanisms to form persister cells in different phases, among which is the toxin-antitoxin (TA) systems. This study aimed at investigating the expression of type II TA system genes under the stress of ciprofloxacin and colistin antibiotics in the exponential and stationary phases.Methods: To determine the effects of ciprofloxacin and colistin on persister cell formation in the exponential and stationary phases of Pseudomonas aeruginosa strains, colony counting was performed at different time intervals in the presence of 5-fold MIC of ciprofloxacin and colistin. In addition, the expression of relBE, Xre-COG5654, vapBC, and Xre-GNAT genes in P. aeruginosa isolates was assessed 3.5 h after antibiotic treatment in the exponential and stationary phases using qRT-PCR.Results: Our results indicated the presence of persister phenotype of P. aeruginosa strains in the presence of 5-fold MIC of ciprofloxacin and colistin compared to the control after 3.5 h of incubation in the exponential and stationary phases. Also, the number of persister cells in the stationary phase was higher than that of the exponential phase. According to the results of qRT-PCR, ciprofloxacin and colistin may induce persister cells by increasing the expression of type II TA systems in stationary and exponential phases.Conclusion: Ciprofloxacin and colistin may increase the formation of persister cells by affecting the expression of type II TA systems.
Body Composition and Nuchal Skinfold Thickness in Pediatric Brain Tumor Patients
Authors: Peng Junxiang , Boekhoff Svenja , Eveslage Maria , Bison Brigitte , Sowithayasakul Panjarat , Muller Hermann 
Published: January 2021

Abstract
Background: Obesity, cardiovascular disease (CVD), and relapse/progression have impact on prognosis in pediatric brain tumor (BT) patients. Methods: In a cross-sectional study, we analyzed nuchal skinfold thickness (NST) on MRI follow-up monitoring as a parameter for body composition (BC) and CVD in 177 BT patients (40 WHO grade 1–2 BT; 31 grade 3–4 BT; 106 craniopharyngioma (CP)), and 53 healthy controls (HC). Furthermore, BMI, waist-to-height ratio (WHtR), caliper-measured skinfold thickness (cSFT), and blood-pressure (BP) were analysed.Results: CP patients showed higher BMI, WHtR, NST and cSFT when compared with BT and HC. WHO grade 1–2 BT patients were observed with higher BMI, waist circumference and triceps cSFT when compared to WHO grade 3–4 BT patients. NST correlated with BMI, WHtR, and cSFT. NST, BMI and WHtR had predictive value for CVD in terms of increased BP. In multivariate analysis, only BMI was selected for the final model resulting in an odds ratio of 1.25 (1.14–1.379). In CP patients with hypothalamic involvement/lesion or gross-total resection, rate and degree of obesity were increased. Conclusions: NST could serve as a novel useful parameter for assessment of BC and CVD risk in BT patients.