bluuebunny/crossref_metadata_2025_split huggingface dataset:
United States Under-19 Rugby-7s: Incidence and Nature of Match Injuries During a 5-year Epidemiological Study
Authors: Lopez Victor , Ma Richard , Weinstein Meryle G. , Hume Patria A. , Cantu Robert C. , Victoria Christian , Queler Sophie C. , Webb Khalil J. A. , Allen Answorth A. 
Published: August 2020

Abstract
Background
There is a lack of injury data for the new Olympic sport of Rugby-7s, particularly for involved youth.

Objective
To determine injury rates and characteristics for players participating in U.S. Rugby-7s U19 (under 19 years of age) tournaments.

Methods
Injury data were collected, using the Rugby Injury Survey & Evaluation report methodology, at 24 U.S. Rugby-7 s U19 tournaments over 30 tournament days (2010–2014). Tournament medical-attention injuries and time-loss injuries (days absent before return to training/competition including post tournament) were recorded.

Results
During the 2101 playing hours (3072 males, aged 17.2 ± 1.5 years; 732 females, 16.6 ± 1.3 years of age), there were 173 tournament injuries with an overall injury incidence of 82.4/1000 player-match-hours (ph) (CI 70.5–95.6). Acute injuries (79.5/1000 ph) occurred during tackling (56.2/1000 ph) and involved joints/ligaments (32.8/1000 ph) of lower extremities (31.9/1000 ph). Head and neck injuries, including concussions, were common (males 21.9/1000 ph; females 22.0/1000 ph). Medical-attention injury incidences (49.5/1000 ph; n = 104; 95% CI 40.5–60.0) were higher than time loss (32.8/1000 ph; n = 69; 95% CI 25.5–41.6). Overall, injury incidences found no difference between sex (RR 0.78; p = 0.369). Time-loss injuries resulted in an average of 35.5 d to return to sport.

Discussion
This study is the first to report match injury incidences for U19 participants in Rugby-7s. Overall, match injury incidence among U.S. U19 Rugby-7s tournaments was similar compared to adult U.S. community Rugby-7s. Recurrent injury risk was notable in this population. Community injury surveillance studies are essential to understand risk from participation in amateur sports. Knowledge of these injury patterns in U19 Rugby-7s will help identify areas to direct resources to enable growth of Rugby-7s in youths and emerging countries being exposed to Rugby-7 s. Age-based injury frequency and patterns in rugby and its various formats are needed for the development of evidence-based, sport-specific, and population-specific injury prevention initiatives.

Conclusions
The match injury incidence of U19 participants in U.S. Rugby-7s was similar to the incidence among adult participants. Recurrent match injury risk was high at 23%. There were no significant differences in injury incidences between males and females. The first three matches of a tournament day result in the most injuries.
Bond strength and marginal adaptation of a novel root-end filling material
Authors: Aly Yousra , El Shershaby Sherif , El-Sherif Sammar 
Published: August 2020

Abstract
Background
Apicoectomy with retrograde filling is considered as a tooth saver. Mineral trioxide aggregate (MTA) is mostly recommended as a root-end filling material as it is proved to have excellent sealing ability and hard tissue repair. Aside from these advantages, MTA has some disadvantages, such as weak handling properties, long setting time, and discoloration potential. Nanotechnology is now undergoing rapid development. Recently, experimental nano-white mineral trioxide aggregate (nano-WMTA) was prepared and introduced by NanoTech Egypt (Al Giza, Egypt) as a root-end filling material. The manufacturers claim that it has similar composition to white MTA, but with the reduction of its particle size to obtain a high specific powder surface area that may lead to a better and faster hydration process. It seems worthy to study the bond strength and marginal adaptation of the newly introduced nano root-end filling materials and compare it with the conventionally used MTA in root-end cavities.

Results
In push-out test, no statistically significant difference was found between nano-WMTA and MTA Angelus groups where p = 0.459. The nano-WMTA group recorded the highest mean value. For scanning electron microscope evaluation, there was a statistically significant difference between the nano-WMTA and MTA Angelus groups where p < 0.001. The MTA Angelus group recorded the highest mean value of gap distance.

Conclusions
Nano-WMTA recorded a similar bond strength to MTA Angelus. The nano-WMTA showed significantly higher marginal adaptation to root-end cavity than MTA Angelus.
Monitoring and analysis of rice pathogen Ustilaginoidea virens isolates with resistance to sterol demethylation inhibitors in China
Authors: Pan Xiayan , Cao Huijuan , Yu Junjie , Yu Mina , Qi Zhongqiang , Song Tianqiao , Du Yan , Yong Mingli , Zhang Rongsheng , Yin Xiaole , Liu Yongfeng 
Published: August 2020

AbstractRice false smut (RFS), caused by Ustilaginoidea virens (Cooke) Takah, is an important fungal disease of rice. In China, sterol demethylation inhibitors (DMIs) are common fungicides used to control RFS. In a previous study, we detected two propiconazole-resistant U. virens isolates in 2015 in Huai’an city, Jiangsu Province, China. In the current study, we detected six propiconazole-resistant isolates out of 180 U. virens isolates collected from rice fields in Jiangsu Province in 2017, and found they were from three different places (Xuzhou, Huai’an and Jintan). All these six propiconazole-resistant isolates were cross-resistant to three other sterol demethylation inhibitor (DMI) fungicides, i.e. difenoconazole, tebuconazole, and epoxiconazole. Among them, two isolates (2017–61 and 2017–170) had high fitness. Through sequencing and RT-qPCR analysis, we found that the expression levels of CYP51 and its encoded protein were significantly increased in the propiconazole-resistant isolates with a “CC” insertion mutation upstream of the CYP51 coding region compared to the propiconazole-sensitive isolates. In addition, propiconazole stimulated CYP51 expression in all isolates. Propiconazole also stimulated the accumulation of CYP51 protein in propiconazole-sensitive isolates and propiconazole-resistant isolates without mutation, but not in propiconazole-resistant isolates with the “CC” mutation. According to JASPAR database analysis, the predicated functional binding sites for propiconazole-resistant isolates with a “CC” insertion mutation and propiconazole-sensitive isolates were different. Given the high fitness of the propiconazole-resistant isolates, the development of resistance to DMIs in U. virens should be monitored. Furthermore, we speculated that the over-expression of CYP51 may contribute to DMI resistance in U. virens with the “CC” insertion mutation.
DWI as a biomarker of renal function in children with CKD: what is the potential?
Authors: Emad-Eldin Sally , Yadav Sunil , Galal Rasha Essam Eldin , Elzayat Wessam Abdelrahman 
Published: August 2020

Abstract
Background
Evaluation of renal microstructure is pivotal for diagnosing and monitoring chronic renal disease. DWI has been proved to be practicable and reliable examination for the assessment of renal function and parenchymal damage in some renal diseases. Our aim is to appraise DWI sequence and ADC measurement as a potential tool of renal function assessment as well as establishing a possible relationship between the different CKD stages and the renal parenchymal ADC values changes.

Results
Regarding the cause of CKD, nine patients (45%) had glomerulonephritis, 5 patients (25%) had hemolytic uremic syndrome, 2 patients (10%) had lupus nephritis, 2 patients (10%) had nepheronophthisis, and 1 patient (1.5%) had infantile nepherosis, whereas the cause of CKD was unknown in 1 patient (1.5%).
The stages of CKD were classified according to KIDGO guidelines: 6 patients (30%) were stage 1, 4 patients (20%) were stage 2, 3 patients (15%) were stage 3, 2 patients (10%) were stage 4, and 5 patients (25%) were stage 5. The patients’ group (group A) had a mean ADC value (1.85 × 10−3 ± 0.24) which was significantly lower than that of the control group (group B) (2.21 × 10−3 ± 0.12). As for the correlation between stage of CKD and ADC, we found it to be a moderate negative one with r’ value of − .655 and a significant p value of < 0.001.

Conclusion
DWI is recognized as a promising imaging tool that can take part in the assessment of the morphological and functional changes in diffuse renal parenchymal disease, hence playing an important role in the early diagnosis and staging of chronic kidney disease.
Revisiting early-stage COVID-19 strategy options
Authors: Machanick Philip 
Published: August 2020

Background: Early-stage interventions in a potential pandemic are important to understand as they can make the difference between runaway exponential growth that is hard to turn back and stopping the spread before it gets that far. COVID19 is an interesting case study because there have been very different outcomes in different localities. These variations are best studied after the fact if precision is the goal; while a pandemic is still unfolding less precise analysis is of value in attempting to guide localities to learn lessons of those that preceded them. Methods: I examine three factors that could differentiate strategy: asymptomatic spread, differences in use of the Bacillus Calmette-Guerin (BCG) tuberculosis vaccine and cloth face masks. Results: Differences in disease progression as well as the possibility of alternative strategies to prevent COVID-19 from entering the runaway phase or damping it down later can be elucidated by a study of asymptomatic infection. A study to demonstrate not only what fraction are asymptomatic but how contagious they are will also inform policy on universal mask wearing. Conclusions: While a COVID-19 outbreak is at a level that makes accurate trace-and test possible, investigation of asymptomatic transmission is viable and should be attempted to enhance understanding of spread and variability in the disease as well as policy options for slowing the spread.
A identidade brasiliense na variação lexical da estrutura urbana do Plano Piloto
Authors: Maia Pires Flávia de Oliveira 
Published: August 2020

Este trabalho é parte de um estudo sobre o léxico da estrutura urbana e arquitetônica do Plano Piloto de Brasília, no âmbito dos estudos lexicais e terminológicos. Identificou-se variações entre os itens lexicais que denominam a estrutura urbana e arquitetônica, utilizados pelos habitantes da capital do Brasil, revelando marcas identitárias do brasiliense em conversas cotidianas que envolvem a cidade. As variações lexicais englobam siglas, nomes complexos e nomes simples. A pesquisa demonstra que as variações estão sujeitas ao contexto de uso. Utilizou-se a metodologia analítica-descritiva. O corpus foi formado por textos especializados, textos de divulgação e sites governamentais sobre Brasília. A ferramenta AntConc (ANTHONY, 2019) auxiliou no processamento dos dados. As bases para este trabalho foram a teoria da terminologia variacionista de Faulstich (1996, 1997, 1998 e 2001) e estudos de Maia-Pires (2009 e 2018). O primeiro estudo, incluindo as variações lexicais, registrou um conjunto de 216 nomes que compunham o léxico urbanístico do Plano Piloto, a etapa mais recente acrescentou 54 nomes, incluindo elementos arquitetônicos, formando um total de 270 itens lexicais que estão divulgados em um glossário, publicado em abril de 2018.
Experience with citicoline in patients with post-stroke cognitive impairment
Authors: Bogolepova A. N. , Burd S. G. , Lebedeva A. V. , Kovalenko E. A. 
Published: August 2020

Objective: to investigate the efficacy and safety of citicoline (Ceresil® Canon) in patients with post-stroke cognitive impairment.Patients and methods. Examinations were made in 33 patients aged 45 years and older who had experienced primary ischemic hemispheric stroke with complaints of a decline in memory or other cognitive functions. The cognitive status was assessed using the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). The presence of anxiety-depressive spectrum disorders was determined on the Hospital Anxiety and Depression Scale. All the patients received citicoline (Ceresil® Canon) oral solution at a dose of 1000 mg/day for 3 months.Results and discussion. Citicoline administration showed a statistically significant reduction in the severity of cognitive impairment (p<0.001). The time course of positive changes in the cognitive status of patients was reflected by an increase in the median score on the MMSE from 26 [25; 27.5] to 28 [26.5; 29] and on MoCA from 23 [21; 25] to 25 [22; 26]. There was a decline in the number of patients with anxiety-depressive disorders. No adverse events or side effects were found in the patients.Conclusion. The findings suggest that citicoline (Ceresil® Canon) produced as an oral solution is well tolerated and improves cognitive functions and affective sphere in patients in the recovery period of ischemic stroke.
Depressions with eating disorders: clinical manifestations and therapy
Authors: Medvedev V. E. , Frolova V. I. , Gushanskaya E. V. , Fofanova Yu. S. , Martynov S. E. , Zuikova N. L. , Burno A. M. , Nekrasova S. V. , Salyntsev I. V. 
Published: August 2020

Depression is a common comorbid diagnosis in patients with eating disorders (EDs). The development of pathogenetic therapy for depression with EDs is far from being completed.The objective of the psychopharmacotherapeutic study was to evaluate the efficacy and tolerability of melatonergic monotherapy with the antidepressant agomelatine (25–50 mg/day at night) for depressions with two ED variants: hyperphagic (n=32) and hypo- and aphagic (n=31) EDs.Patients and methods. The investigation enrolled patients of both sexes, aged 18 to 65 years. The investigators performed clinical psychopathological and experimental psychological studies, as well as psychometric examination using the 21-item Hamilton Depression Rating Scale (HDRS-21), the Clinical Global Impression (CGI), the Supplemental Hospital Offset Payment Program (SHOPP), the Dutch Eating Behavior Questionnaire (DEBQ), and statistical data processing.Results and discussion. There was a significant pronounced antidepressant effect of 6-week agomelatine therapy for depressions occurring with different ED variants both in the pattern of the depressive symptom complex and in that of concurrent with and preceding the latter. At the same time, the efficacy of the drug did not depend on the clinical presentations of the leading hypothymic syndrome, the variants of EDs, and the duration of actual depression. However, by the end of the study period, a larger effect was achieved in the therapy for depressions with the hyperphagic variant of EDs, as well as in patients with EDs manifesting in the pattern of depressive symptom complex. Agomelatine has a favorable tolerance profile. BMI tends to become normal in patients with different variants of EDs during the therapy. The adverse events are transient and/or unclear; they do not require therapy discontinuation.Conclusion. Agomelatine is an effective and relatively safe drug that can be recommended to treat depressions concurrent with EDs in therapeutic dosages for at least 6 weeks.
The main clinical and diagnostic characteristics of patients with low back pain and sacroiliac joint diseases (results of the IOLANTA-II study)
Authors: Zolotovskaya I. A. , Davydkin I. L. 
Published: August 2020

Objective: to investigate the clinical and diagnostic characteristics of patients with low back pain in the presence of sacroiliac joint (SIJ) disease.Patients and methods. The investigation design involved three visits: V 1 (inclusion); V 2 (after 7 days), and V 3 (after 3 months); after the screening period, the investigation enrolled 259 patients aged 65.5 [62.5; 69.5] years; of them there were 165 (63.7%) women. At V 1 , according to magnetic resonance imaging findings, the patients were divided into two groups: 1) 157 patients without confirmed SIJ disease; 2) 102 patients with confirmed SIJ disease. During all visits, the investigators made general clinical and neurological examinations and assessed the intensity of pain syndrome according to a visual analogue scale (VAS) for pain in millimeters, a neuropathic pain component according to the DN4 questionnaire, by determining the blood parameters: transforming growth factor-β1 (TGF-β1), interleukin-1β (IL-1β), IL-6, Beta-Crosslaps, the indicator of bone matrix formation procollagen type 1 N-terminal propeptide (P1NP) and by estimating the urinary level of deoxypyridinoline.Results and discussion. At all visits, Group 2 patients with higher VAS pain scores had a pain history that was statistically significantly longer (p<0.001). The ANOVA analysis showed that the patients in Group 2 had statistically significantly higher values of TGF-β1, IL-1β, IL-6, and bone resorption markers than those in Group 1, which suggests the relationship between pain syndrome and the presence of an inflammatoryresorptive process in patients with SIJ disease.Conclusion. A high (39.4%) prevalence of SIJ disease was noted in patients over 60 years of age with low back pain. During the follow-up period, there was a decrease in bone resorption markers and cytokines; however, the SIJ disease group showed less pronounced changes with statistically significant differences in all parameters than in the non-SIJ disease group. It is advisable to consider an algorithm for diagnosing a patient over 60 years of age with low back pain, by mandatorily examining his/her SIJ. Treatment policy, including methods for correction with drugs, should be discussed based on the findings.
Disponibilidad de productos agropecuarios de la Feria del Agricultor de San Ramón, Alajuela, Costa Rica
Authors: Sánchez-Brenes Ronald , Arboleda-Julio Esteban 
Published: August 2020

Las ferias del agricultor costarricenses son centros de distribución y abastecimiento de productos agropecuarios, los cuales pueden contribuir a la seguridad alimentaria y nutricional de Costa Rica. En la presente investigación se planteó medir la disponibilidad, estacionalidad y frecuencia de los productos agropecuarios de la Feria del Agricultor de San Ramón (FASR), con el fin de que la FASR pueda ofrecer la disponibilidad física de los alimentos a su público consumidor. Se registraron un total de 165 productos agropecuarios en los tramos de comercialización, en un periodo de un año (noviembre 2015-octubre 2016). De la totalidad de productos agropecuarios observados, 35 % corresponde a frutas, 21 % a hortalizas o verduras, 21 % a plantas medicinales y aromáticas, 9 % a raíces feculentas y otros alimentos con alto contenido de carbohidratos, 7 % a productos de origen animal, 4 % a legumbres y 3 % a otros.
The effect of six weeks CoBAgi training on coordination, dynamic balance & agility of adolescent handball players
Authors: Mohamad Puzi Mohamad Hasif B. , Choo Lee A. 
Published: August 2020

Background and Study Aim. The aim of this study is to investigate the effects CoBAgi Training which apply neuromuscular training, sport specific movements that couple with perturbation variation on coordination, dynamic balance and agility among adolescent handball players.
Material and Methods. Quantitative randomized controlled trials quasi-experimental design with pretest and posttest evaluation used for this study. A total of 30 adolescent handball players (aged: 14.00 ± 0.83 years) were recruited as participants. Purposive sampling methods were used for these purposes. The participants were randomly assigned into two groups i.e. control group (CG: n=15) and experimental group (EG: n=15). EG undergone six weeks CoBAgi training while CG followed their usual training routine with supervision of the researcher, there times a week for 6 weeks. In order to measure the effect of these training on coordination, dynamic balance and agility, participants have performed Carioca Test, Star Excursion Balance Test (SEBT) and L-Run Test during pre-training and post-training session. The data were analyzed through Independent Samples t-test with p<0.05 “Statistical Package for the Social Sciences” (SPSS) program.
Result. After completed the six weeks training duration, there were significant difference identified in coordination (t=-2.290, P=0.030*), dynamic balance (t= 4.802, P=0.000*) and agility (t=-3.202, P= 0.003*) between EG and CG.
Conclusion. Therefore, this study revealed that CoBAgi training could improve abilities performance of coordination, dynamic balance and agility, and this suggesting that CoBAgi training may be use as rehabilitation and pre-rehabilitation training strategies in order for injury prevention plan as well as improve sports performance especially among the adolescent handball players.
Confiabilidade e validade concorrente da escala de mobilidade hospitalar em pacientes após acidente vascular cerebral
Authors: Maso Iara , Mascarenhas Laísa , Makhoul Marina , Vasconcelos Lara , Monteiro Maiana , Jesus Pedro , Oliveira Filho Jamary , Pinto Elen Beatriz Carneiro 
Published: August 2020

INTRODUÇÃO: A Escala de Mobilidade Hospitalar (EMH) avalia de forma específica a mobilidade de pacientes após AVC no ambiente hospitalar e em estudo prévio foi demonstrada a sua concordância interexaminadores, validade preditiva e a responsividade a mudanças na fase aguda. OBJETIVO: avaliar a validade concorrente da EMH e a sua confiabilidade ao ser aplicada através de entrevista. MATERIAIS E MÉTODOS: Trata-se de um estudo de validação, desenvolvido com pacientes internados em uma Unidade de AVC na cidade de Salvador-Bahia. Para avaliar a validade concorrente da EMH comparamos o seu escore com a pontuação da Escala de Rankin modificada utilizando o teste de Spearman. Ambas escalas foram aplicadas no quinto dia após o AVC pelo mesmo pesquisador, previamente treinado. Para avaliação da confiabilidade da EMH quando aplicada através de entrevista, a escala foi aplicada por dois examinadores em turnos diferentes, no mesmo dia. O primeiro examinador aplicou a escala através da observação do desempenho e o segundo examinador através de entrevista. Utilizamos para esta análise o Coeficiente de Correlação Intraclasse (CCI). RESULTADOS: A pontuação total da EMH apresentou uma correlação positiva muito forte com a ERm (r=0,90) e também foi encontrada uma correlação significativa entre os subitens da EMH e a ERm. Ao comparar a aplicação da EMH através da observação do desempenho e aplicação por entrevista, observamos uma excelente concordância interexaminadores (CCI > 0,90). CONCLUSÃO: A Escala de Mobilidade Hospitalar, projetada especificamente para pacientes após AVC, mostrou um alto grau de validade concorrente e se mostrou confiável quando aplicada através de entrevista.
ORNAMEN DEKORASI KUBAH DALAM MASJID AL-HIDAYAH KARANGPLOSO-MALANG
Authors: Ratnawati Dwi , Indrawati Lilik , Sidyawati Lisa 
Published: August 2020

Masjid Al-Hidayah Karangploso memiliki bentuk menyerupai masjid Suleyman I di Turki, dengan ornament dekorasi kubah dalam yang beragam dan menjadi point of view ruang utama. Tujuan penelitian ini adalah mengidentifikasi visualisasi dan mengklasifikasikan ornament dekorasi kubah dalam. Penelitian ini menggunakan metode penelitian deskriptif kualitatif. Pada penelitian ini ditemukan sepuluh ornamen pada empat pola bidang dengan frekuensi kemunculan berbeda. Kesepuluh ornamen tersebut diklasifikasikan menjadi tiga jenis yakni ornament geometris, kaligrafi, dan arabes. Hasil penelitian menunjukkan bahwa ornament suluts muncul paling banyak dan tidak ditemukan ornament dengan bentuk timur tengah.