bluuebunny/crossref_metadata_2025_split huggingface dataset:
Paper‐Based Ratiometric Fluorescence Analytical Devices towards Point‐of‐Care Testing of Human Serum Albumin
Authors: Luo Zijie , Lv Taoyuze , Zhu Kangning , Li Yi , Wang Lei , Gooding J. Justin , Liu Guozhen , Liu Bin 
Published: December 2019

AbstractMonitoring of human serum albumin (HSA) in a point‐of‐care fashion is urgently needed in particular for elderly or chronically ill patients. Herein, a dual‐state emissive chalcone probe having the feature of aggregation‐induced emission was designed and synthesized. The concentration of HSA can be evaluated by the ratios of emission from probes in aggregated and monomeric state, which gives a visually discernible red‐to‐green color change. A simple, portable paper‐based analytical device have been fabricated by integration of the recognition probe in the detection pad and employed for HSA test using the whole blood samples. This paper‐based assay shows the analytical capability comparable to the standard testing methods but is in a point‐of‐care fashion, providing a promising tool for at‐home HSA detection and HSA‐related disease diagnosis.
The Detection and Reactivity of Silanols and Silanes Using Hyperpolarized 29Si Nuclear Magnetic Resonance
Authors: Rayner Peter J. , Richardson Peter M. , Duckett Simon B. 
Published: December 2019

AbstractSilanols and silanes are key precursors and intermediates for the synthesis of silicon‐based materials. While their characterization and quantification by 29Si NMR spectroscopy has received significant attention, it is a technique that is limited by the low natural abundance of 29Si and its low sensitivity. Here, we describe a method using p‐H2 to hyperpolarize 29Si. The observed signal enhancements, approaching 3000‐fold at 11.7 T, would take many days of measurement for comparable results under Boltzmann conditions. The resulting signals were exploited to monitor the rapid reaction of tris(tert‐butoxy)silanol with triflic anhydride in a T1‐corrected process that allows for rapid quantification. These results demonstrate a novel route to quantify dynamic processes and intermediates in the synthesis of silicon materials.
A Neutrophil‐Inspired Supramolecular Nanogel for Magnetocaloric–Enzymatic Tandem Therapy
Authors: Zhang Qi , Wu Jiaojiao , Wang Jingjing , Wang Xia , Wu Chu , Chen Mengwei , Wu Qing , Lesniak Maciej S. , Mi Yongli , Cheng Yu , Wang Qigang 
Published: December 2019

AbstractNeutrophils can responsively release reactive oxygen species (ROS) to actively combat infections by exogenous stimulus and cascade enzyme catalyzed bio‐oxidation. A supramolecular nanogel is now used as an artificial neutrophil by enzymatic interfacial self‐assembly of peptides (Fmoc‐Tyr(H2PO3)‐OH) with magnetic nanoparticles (MNPs) and electrostatic loading of chloroperoxidase (CPO). The MNPs within the nanogel can elevate H2O2 levels in cancer cells under programmed alternating magnetic field (AMF) similar to the neutrophil activator, and the loaded CPO within protective peptides nanolayer converts the H2O2 into singlet oxygen (1O2) in a sustained manner for neutrophil‐inspired tumor therapy. As a proof of concept study, both the H2O2 and 1O2 in cancer cells increase stepwise under a programmed alternating magnetic field. An active enzyme dynamic therapy by magnetically stimulated oxygen stress and sustained enzyme bio‐oxidation is thus shown with studies on both cells and animals.
Photodissociation Mechanisms of Major Mercury(II) Species in the Atmospheric Chemical Cycle of Mercury
Authors: Francés‐Monerris Antonio , Carmona‐García Javier , Acuña A. Ulises , Dávalos Juan Z. , Cuevas Carlos A. , Kinnison Douglas E. , Francisco Joseph S. , Saiz‐Lopez Alfonso , Roca‐Sanjuán Daniel 
Published: December 2019

AbstractMercury is a contaminant of global concern that is transported throughout the atmosphere as elemental mercury Hg0 and its oxidized forms HgI and HgII. The efficient gas‐phase photolysis of HgII and HgI has recently been reported. However, whether the photolysis of HgII leads to other stable HgII species, to HgI, or to Hg0 and its competition with thermal reactivity remain unknown. Herein, we show that all oxidized forms of mercury rapidly revert directly and indirectly to Hg0 by photolysis. Results are based on non‐adiabatic dynamics simulations, in which the photoproduct ratios were determined with maximum errors of 3%. We construct for the first time a complete quantitative mechanism of the photochemical and thermal conversion between atmospheric HgII, HgI, and Hg0 compounds. These results reveal new fundamental chemistry that has broad implications for the global atmospheric Hg cycle. Thus, photoreduction clearly competes with thermal oxidation, with Hg0 being the main photoproduct of HgII photolysis in the atmosphere, which significantly increases the lifetime of this metal in the environment.
Synthesis and non‐parametric evaluation studies on high performance of catalytic oxidation‐extraction desulfurization of gasoline using the novel TBAPW11Zn@TiO2@PAni nanocomposite
Authors: Khanmohammadi Khorrami Mohammad Reza , Shokri Aghbolagh Zahra 
Published: December 2019

In this work, the new catalyst (assigned as TBAPW11Zn@TiO2@PAni) was successfully designed and synthesized on the basis of quaternary ammonium salt of zinc monosubstituted phosphotungstate [(n‐C4H9)4N][PW11ZnO39] (TBAPW11Zn), titanium dioxide (TiO2), and polyaniline (PAni). This study reports the catalytic oxidation‐extraction desulfurization (ECODS) of sulfur‐containing molecules from real and the simulated (Th, BT, and DBT) gasoline using new organic–inorganic hybrid catalyst (TBAPW11Zn@TiO2@PAni). The ECODS results were shown that the concentration of sulfur compounds (SCs) of real gasoline was lowered from 0.4992 to 0.0122 wt.% with 97% efficiency at 35 °C after 1 h. Furthermore, the synthesized heterogeneous nanocatalyst showed high stability and reusability after five times without significant loss of activity. The high performance of TBAPW11Zn@TiO2@PAni/H2O2/CH3CO2H system can be a promising route with a superb potential in the generation of ultra‐low‐sulfur gasoline. Also the Mann–Whitney U‐test results show that there is not a significant difference between the mean of sulfur percentage for DBT & BT, BT & Th and DBT & Th in the presence of the catalyst. Based on the Kruskal–Wallis test results, we can conclude that the temperature, time and amount of catalyst have a significant effect on ECODS efficiency of TBAPW11Zn@TiO2@PAni nanocomposite.
Ultrasonic welding of all‐polypropylene composites
Authors: Kiss Zoltán , Temesi Tamás , Bitay Enikő , Bárány Tamás , Czigány Tibor 
Published: December 2019

ABSTRACTIn this study, the mechanical properties of ultrasonic welded lap joints of all‐polypropylene composite (APPC) were investigated and compared to the interlaminar properties of the composite sheet itself. The process control parameter was welding time: welded samples were prepared with an ultrasonic welding machine in the 0.1–1.0 second time range. In most cases, the shear strength of the welded samples exceeded that of the unwelded APPC. Although it was found that during the ultrasonic welding process, the reinforcing tapes partially melted in the welding zone (WZ), the seam remained strong enough because the heat released and the pressure applied during the welding process further improved the consolidation of the APPC layers. © 2019 The Authors. Journal of Applied Polymer Science published by Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48799.
One‐step fabrication of superhydrophobic P(VDF‐co‐HFP) nanofibre membranes using electrospinning technique
Authors: Tas Mahmut , Xu Fang , Ahmed Ifty , Hou Xianghui 
Published: December 2019

ABSTRACTIn this study, superhydrophobic electrospun P(VDF‐co‐HFP) membranes were fabricated in a one‐step electrospinning process. The effects of the key parameters of electrospinning (solution concentration, electrical potential, flow rate, and solvent) on the surface roughness, fiber formation, and hydrophobicity of the membranes were evaluated using Taguchi method. A 4 × 3 orthogonal array was utilized, and the results indicated that the solvent played the critical role in producing the superhydrophobic nanofibre membranes. It was demonstrated that it is possible to produce superhydrophobic membranes with P(VDF‐co‐HFP) without additional functionalisation and fillers. The highest water contact angle and the lowest contact angle hysteresis obtained were 156° and 5°, respectively, and the roughness values varied from 0.15 to 5.74 μm for the produced P(VDF‐co‐HFP) nanofibre membranes. The surface superhydrophobicity of the membranes was attributed to the specific structures consisting of a combination of beads and nanofibres. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48817.
The Proportion of Fe‐NX, N Doping Species and Fe3C to Oxygen Catalytic Activity in Core‐Shell Fe‐N/C Electrocatalyst
Authors: Liu Yanyan , Zhu Yihua , Jiang Hongliang , Shen Jianhua , Li Chunzhong 
Published: December 2019

AbstractA bifunctional oxygen electrocatalyst composed of iron carbide (Fe3C) nanoparticles encapsulated by nitrogen doped carbon sheets is reported. X‐ray photoelectron spectroscopy and X‐ray absorption near edge structure revealed the presence of several kinds of active sites (Fe−Nx sites, N doping sites) and the modulated electron structure of nitrogen doped carbon sheets. Fe3C@N‐CSs shows excellent oxygen evolution and oxygen reduction catalytic activity owing to the modulated electron structure by encapsulated Fe3C core via biphasic interfaces electron interaction, which can lower the free energy of intermediate, strengthen the bonding strength and enhance conductivity. Meanwhile, the contribution of the Fe−Nx sites, N doping sites and the effect of Fe3C core for the electrocatalytic oxygen reaction is originally revealed. The Fe3C@N‐CSs air electrode‐based zinc‐air battery demonstrates a high open circuit potential of 1.47 V, superior charge‐discharge performance and long lifetime, which outperforms the noble metal‐based zinc‐air battery.
Observer‐based compensation control of servo systems with backlash
Authors: Sun Guofa , Zhao Jingbo , Chen Qiang 
Published: December 2019

AbstractFor compensating backlash phenomenon in servo systems, the authors propose an observer method in this paper to estimate both system states and vibration torque before controller design. First, a systematic scheme is given to obtain plant parameters, which is very important in observing system states. This is a parameter estimation principle that gives a crude estimation and computes the differences between the crude and true values. As a result, the precise value of the parameters is obtained by adding together the crude value and the difference. Then, based on the precise estimated parameters, an extended state observer (ESO) is designed to obtain feedback and feedforward signals. Consequently, robust compensation control is achieved by designing an output feedback controller, consisting of a feedback term and a feedforward term. Finally, in order to validate the proposed approach, extensive experiments are performed on a practical servo system with backlash nonlinearity.
Tailoring the Charge/Discharge Potentials and Electrochemical Performance of SnO2 Lithium‐Ion Anodes by Transition Metal Co‐Doping
Authors: Birrozzi Adele , Asenbauer Jakob , Ashton Thomas E. , Groves Alexandra R. , Geiger Dorin , Kaiser Ute , Darr Jawwad A. , Bresser Dominic 
Published: December 2019

AbstractIt has been shown that the introduction of several transition metal (TM) dopants into SnO2 lithium‐ion battery anodes can overcome the issues associated with the irreversible capacity loss from the conversion reaction of SnO2 and the aggregation of the metallic Sn particles formed upon lithiation. As the choice of the single dopant, however, plays a decisive role for the achievable energy density – precisely its redox potential – we investigate herein TM co‐doped SnO2, prepared by using a readily scalable continuous hydrothermal flow synthesis (CHFS) process, to tailor the dis‐/charge profile and by this the energy density. It is shown that the judicious choice of different elemental doping combinations in samples made via CHFS simultaneously improves the cycling performance and the full‐cell energy density. To support these findings, we realized a lithium‐ion full‐cell incorporating the best performing co‐doped SnO2 as negative electrode and high‐voltage LiNi0.5Mn1.5O4 (LNMO) as positive electrode–to the best of our knowledge, the first full‐cell based on such anode material in combination with LNMO as cathode active material.
The monster of Ascheraden: A description of syndromic cryptophthalmos by poet Daniel Hermann in “De monstroso partu…” published in Riga, 1596
Authors: Lībiete Ieva 
Published: December 2019

AbstractIn 1596, the Niclas Mollyn (Nicolaus Mollinus; 1550/55–1625) printing house in Riga, published a book in Latin, authored by Prussian poet and humanist Daniel Hermann (1543–1601) with quite an intriguing title “De monstroso partu…” or “About the monstrous birth: on August 18 of the year 1595 in the district of Ascheraden on the other side of the Duna in Livonia and on things that happen against the laws of nature. An ethical, natural and historical discourse.” The “Monstroso partu…” is among the earliest books printed in Riga and the first one dedicated to a medical topic. The book contains what could be seen as the earliest known description of syndromic cryptophthalmos aka Fraser syndrome.
Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats
Authors: Zhang Li , Huang Li , Wang Jingxian , Zhang Muchun , Zhang Ye , Hu Xianwen 
Published: December 2019

AbstractBackgroundHemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis. Mitochondrial permeability transition pore (mPTP) plays an important role in apoptosis, but it is unknown if the protective effect of sevoflurane postconditioning on hemorrhagic shock and resuscitation is associated with the change of mPTP opening. Hence, the aim of the study was to find out the precise mechanism of the sevoflurane postconditioning.MethodsSprague Dawley rats were subjected to hemorrhage shock for 60 min and then exposed to 2.4% sevoflurane for 30 min at the instant of reperfusion. Additionally, an opener (atractyloside) or an inhibitor (cyclosporine A) of mPTP was used in the animal model before sevoflurane postconditioning. Rats were randomly assigned into groups of Sham, Shock, Shock+Sevoflurane, Shock+Atractyloside, Shock+Sevoflurane+Atractyloside, Shock+Cyclosporin A, and Shock+Sevoflurane+Cyclosporin A treatment. Rat behavior was assessed for 5 days by Morris water maze 72 hr after surgery, and then hippocampus CA1 region was immunohistochemically stained. Brains were harvested 24 hr after surgery to detect the protein expression levels of Bcl‐2, Bax, and cytochrome C by Western blot, the changes of mPTP opening, and mitochondrial membrane potential (MMP).ResultsWe found that sevoflurane postconditioning significantly improved rats' spatial learning and memory ability, down‐regulated the expression of Bax, cytochrome C, and caspase‐3, up‐regulated the expression of Bcl‐2, decreased the mPTP opening, and increased the MMP. The neuroprotective effect of sevoflurane postconditioning was abolished by atractyloside, but cyclosporin A played the similar protective role as sevoflurane postconditioning.ConclusionThese findings proved that sevoflurane postconditioning improved spatial learning and memory ability in hemorrhage shock and resuscitation rats, the mechanism of which may be related to block mPTP opening, increase MMP, and reduce neuron apoptosis in the hippocampus.
Facile Fabrication of Amorphous Molybdenum Oxide as a Sensitive and Stable SERS Substrate under Redox Treatment
Authors: Ma Jiayu , Tan Xianjun , Ma Yunfei , Yao Xinyun , Zhang Jinlong , Wang Lingzhi 
Published: December 2019

AbstractAmorphous MoO3−x nanosheets were fabricated by the room‐temperature oxidation of molybdenum powder with H2O2, followed by light‐irradiation reduction in methanol. When applied as a substrate for surface‐enhanced Raman spectroscopy (SERS), these nanosheets exhibit higher sensitivity than the crystalline counterpart for a wide range of analytes. Moreover, the SERS activity remains stable on repeated oxygen insertion/extraction. In contrast, the performance of crystalline MoO3−x continuously deteriorates on successive redox treatments. This unique SERS activity allows the recycling of the substrate through an H2O2‐based Fenton‐like reaction. More importantly, the non‐invasive SERS was unprecedentedly used for the self‐diagnosis of amorphous MoO3−x as a more selective photocatalyst than its crystalline counterpart.
Electrochemical Crystallization Concept for Succinic Acid Reduces Waste Salt Production
Authors: Kocks Christian , Görtz Jonas , Holtz Arne , Gausmann Marcel , Jupke Andreas 
Published: December 2019

AbstractBio‐based carboxylic acids are promising platform chemicals. State‐of‐the‐art fermentations produce salts of carboxylic acids at neutral pH. Downstream processing of these fermentation broths traditionally involves a pH shift producing waste salts. These waste salts reduce the sustainability and economics of bio‐cased carboxylic acid production. Waste salt production can be avoided by inducing the pH shift electrochemically. Experimental feasibility studies of an electrochemical downstream process and investigations of electrochemically induced nucleation and crystal growth are given. The presented electrochemical downstream concept enables in situ production of succinic acid and simultaneous pH management of pH neutral fermentations without the side production of waste salts.
S‐(4‐Methoxyphenyl)‐4‐methoxybenzenesulfonothioate as a Promising Lead Compound for the Development of a Renal Carcinoma Agent
Authors: Nantes Camilla I. , Pereira Ingrid D. , Bai Ruoli , Hamel Ernest , Burnett James C. , de Oliveira Rodrigo J. , de F. C. Matos Maria , Beatriz Adilson , Yonekawa Murilo K. A. , Perdomo Renata T. , de Lima Dênis P. , Bogo Danielle , dos A. dos Santos Edson 
Published: December 2019

AbstractOrganosulfur compounds show cytotoxic potential towards many tumor cell lines. Disulfides and thiosulfonates act through apoptotic processes, inducing proteins associated with apoptosis, endoplasmic reticulum stress, and the unfolded protein response. Three p‐substituted symmetric diaryl disulfides and three diaryl thiosulfonates were synthesized and analyzed for inhibition of tubulin polymerization and for human cancer cell cytotoxic activity against seven tumor cell lines and a non‐tumor cell line. S‐(4‐methoxyphenyl)‐4‐methoxybenzenesulfonothioate (6) exhibited inhibition of tubulin polymerization and showed the best antiproliferative potential, especially against the 786‐0 cell line, being six times more selective as compared with the non‐tumor cell line. In addition, compound 6 was able to activate caspase‐3 after 24 and 48 h treatments of the 786‐0 cell line and induced cell‐cycle arrest in the G2/M stage at the highest concentration evaluated at 24 and 48 h. Compound 6 was able to cause complete inhibition of proliferation, inducing the death of 786‐0 cells, by increasing the number of cells at G2/M and greater activation of caspase‐3.
Refractory congestive heart failure: when the solution is outside the heart
Authors: Pernias Vicente , González Miguel , Miñana Gema , Górriz Jose Luis , Juan Isabel , Chorro Francisco J. , Sanchis Juan , Núñez Julio 
Published: December 2019

AbstractRefractory congestive heart failure is associated with an ominous prognosis in which the treatments strategies remain scarce and not well validated. In the last years, continuous ambulatory peritoneal dialysis (CAPD) has emerged as a therapeutic alternative in this subset of patients. So far, it has been associated with a significant improvement in functional capacity and quality of life, together with a striking reduction in the risk of readmissions. We present the case of an elderly patient with severe left ventricular dysfunction and severe mitral and tricuspid regurgitation who presents recurrent admissions for anasarca. After its inclusion in a CAPD programme, the patient experienced a marked clinical and biochemical improvement despite the persistence of cardiac abnormalities. CAPD onset translates into greater sodium removal. We want to emphasize the usefulness of this therapy in the management of volume excess in patients with refractory heart failure and renal failure promoting a greater sodium removal compared with traditional diuretic strategies.
Proposed methodology for building‐specific earthquake loss assessment including column residual axial shortening
Authors: Elkady Ahmed , Güell Gerard , Lignos Dimitrios G. 
Published: December 2019

SummaryThis paper proposes methodological developments for quantifying the impact of residual axial shortening of first‐story steel columns on earthquake loss estimations in steel moment‐resisting frame (MRF) buildings. A new formulation is proposed that accounts for the likelihood of having to demolish a steel MRF building due to column residual axial deformations in addition to residual story‐drift ratios. The formulation is informed by means of data from a comprehensive survey conducted worldwide to assess the likelihood of steel column repairability due to residual axial shortening. A practical method for quantifying column axial‐shortening in parameterized system‐level numerical simulations is presented. The proposed approach is illustrated by conducting economic seismic loss estimations in two case‐study steel MRF buildings designed in urban California according to the current seismic design practice. It is found that when the ground‐motion duration is appreciable, the examined steel MRFs are more prone to column axial‐shortening than residual story‐drifts at moderate to high seismic intensities. The results suggest that economic losses due to demolition may be underestimated if column residual axial‐shortening is neglected from loss estimations. Limitations as well as directions for future research are discussed.