bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of the Affordable Care Act on human papillomavirus vaccination initiation among lesbian, bisexual, and heterosexual U.S. women
Authors: Agénor Madina , Murchison Gabriel R. , Chen Jarvis T. , Bowen Deborah J. , Rosenthal Meredith B. , Haneuse Sebastien , Austin Sydney Bryn 
Published: November 2019

AbstractObjectiveTo examine the effect of the 2010 Affordable Care Act (ACA) extended dependent coverage and no cost‐sharing provisions on human papillomavirus (HPV) vaccination in relation to sexual orientation identity among U.S. women.Data Sources2006‐2010 and 2011‐2015 National Survey of Family Growth.Study DesignWe used an interrupted time series design and multivariable Poisson regression to assess differences in HPV vaccination initiation before (2007‐2010) and after (2011‐2015) the 2010 ACA provisions among heterosexual, bisexual, and lesbian U.S. women aged 15‐25 years (N = 7033), adjusting for temporal trends and demographic factors.Data CollectionComputer‐assisted personal interview and audio computer‐assisted self‐interview questionnaires.Principal FindingsThe adjusted prevalence of HPV vaccination initiation was significantly higher among lesbian and bisexual women after compared to before the 2010 ACA—at 19.1 (95% confidence interval [CI]: 5.4, 32.9) and 15.7 (95% CI: 4.4, 27.1) percentage points in 2015 compared to 2007‐2010, respectively. We observed no association between the 2010 ACA provisions and HPV vaccination initiation among heterosexual women after adjusting for temporal trends and demographic factors.ConclusionsThe 2010 ACA provisions may have improved HPV vaccination initiation among lesbian and bisexual women. Policies and programs that increase access to health insurance and provide HPV vaccines at no cost to patients may facilitate HPV vaccine uptake in these marginalized populations.
Retrospective study of the adverse events of the treatment for an acute attack of neuromyelitis optica spectrum disorder
Authors: Veerachit‐O‐larn Titinan , Siritho Sasitorn , Prayoonwiwat Naraporn 
Published: November 2019

AbstractIntravenous methylprednisolone (IVMP) is an initially recommended therapy for an acute attack of neuromyelitis optica spectrum disorder (NMOSD). For those who do not respond to steroid treatment, plasma exchange (PLEX) is generally added‐on. We evaluated adverse events of an acute treatment in NMOSD patients in a university‐based hospital during January 2009 and December 2017. Ninety‐seven patients with 177 attacks were collected. The therapy included IVMP alone (123 events, 62.4%), IVMP followed by PLEX (46 events, 23.4%) and, PLEX alone (8 events, 4.5%). Adverse events occurred in 36.7% of the IVMP group and 61.1% of the PLEX group. The most common adverse event was hyperglycemia (43.5%) followed by infection (29%) in the former and hypocalcemia (63.6%) followed by hypofibrinogen (42.4%), hypotension (30.3%), and infection (21.2%) in the latter. One severe adverse event was documented in the IVMP group and 13 events in the PLEX groups, nevertheless, all were manageable.
Geriatric Nutritional Risk Index as a prognostic marker in patients with extensive‐stage disease small cell lung cancer: Results from a randomized controlled trial
Authors: Lee Gyeong‐Won , Go Se‐Il , Kim Dong‐Wan , Kim Hoon‐Gu , Kim Joo‐Hang , An Ho Jung , Jang Joung Soon , Kim Bong‐Seog , Hahn Seokyung , Heo Dae Seog 
Published: November 2019

BackgroundClinical impact of the Geriatric Nutritional Risk Index (GNRI) in patients with extensive‐stage disease small cell lung cancer (ED‐SCLC) have not previously been reported.MethodsThis study analyzed 352 patients enrolled in a previous randomized phase III trial comparing the efficacy of irinotecan plus cisplatin with that of etoposide plus cisplatin as the first‐line therapy for ED‐SCLC. GNRI values were calculated using serum albumin levels and actual and ideal bodyweights. Patients with a GNRI > 98, 92–98, and <92 were grouped into no, low, and moderate/major risk groups, respectively.ResultsThe objective response rates were 63.2%, 52.6%, and 49.2% in the no, low, and moderate/major risk groups, respectively (P = 0.024). The median progression‐free survival (PFS) was shorter in patients with a lower GNRI than in those with a higher GNRI (no vs. low vs. moderate/major risk group; 6.5 vs. 5.8 vs. 5.9 months, respectively; P = 0.028). There were significant differences in median overall survival (OS) according to GNRI (no vs. low vs. moderate/major risk group; 13.2 vs. 10.3 vs. 8.4 months, respectively; P < 0.001). Multivariate analysis revealed that being in the moderate/major risk group was an independent poor prognostic factor for PFS (hazard ratio [HR]: 1.300, 95% confidence interval [CI]: 1.012–1.670; P = 0.040) and OS (HR: 1.539; 95% CI: 1.069–2.216; P = 0.020).ConclusionsThis prospective study shows that a low GNRI value was associated with a poor prognosis, and it supports the relationship between systemic inflammation, nutritional status, and clinical outcomes in patients with ED‐SCLC.Key pointsSignificant findings of the studyThe lower GNRI group had a low response rate to chemotherapy for ED‐SCLC. The HRs for PFS and OS were 1.300 and 1.539 in the patients with GNRI < 92.What this study addsLow GNRI is associated with poor prognosis in ED‐SCLC.
The effect of cognitive aid design on the perceived usability of critical event cognitive aids
Authors: Clebone Anna , Burian Barbara K. , Tung Avery 
Published: November 2019

BackgroundCritical events require that clinicians process information and make decisions quickly. To reduce mental workload during such events, cognitive aids have been developed. We have previously observed that designing such aids to facilitate discrete information transfer decreased time to information finding. However, whether clinicians perceive aids designed for discrete information transfer as more usable than step‐by‐step designs remains unclear. We hypothesized that experimental cognitive aids designed for discrete information transfer would be judged more usable than step‐by‐step Linear aids.MethodsVolunteer clinicians were asked to use cognitive aids during low fidelity simulation scenarios. Experimental cognitive aids featuring color‐coded, labeled, and consistently located content clusters were compared with aids formatted in a traditional step‐by‐step fashion. We then performed a quantitative assessment of perceived usability and conducted structured knowledge elicitation interviews.ResultsClinicians rated the two experimental cognitive aids as more usable than the Linear aid. On a 0‐100 scale the median (IQR) rating was 25(18,23) for the Linear aid and 89(80,95) and 81(65,90) for the two experimental designs, respectively, with a higher number indicating greater ease of use (P < .01 for each). Narrative responses suggested specific features that improved usability and a thematic analysis identified six major themes driving preference for cognitive aid use.ConclusionDuring simulated critical events, cognitive aids designed for discrete information transfer were considered more usable than step by step Linear aids. Specific themes governing usability were identified during mixed methods analysis. Further work is needed to optimize cognitive aid use among anesthesia clinicians.
Post‐operative intensive care unit admission after elective non‐cardiac surgery: A single‐center analysis of the NSQIP database
Authors: Bruceta Melanio , De Souza Luisa , Carr Zyad J. , Bonavia Anthony , Kunselman Allen R. , Karamchandani Kunal 
Published: November 2019

BackgroundAdmission to the intensive care unit (ICU) after surgery can be associated with significant morbidity and mortality. This observational cohort study aims to identify perioperative factors associated with post‐operative ICU admission in patients undergoing elective non‐cardiac surgery.MethodsData from the ACS NSQIP® database at a tertiary care academic medical center were analyzed from January 2011 to September 2016. Univariable and multivariable logistic regression of patient and surgery‐specific characteristics was performed to assess association with post‐operative ICU admission. The Current Procedural Terminology (CPT) and International Classification of Diseases (ICD‐9) billing codes, as well as associated outcomes, were reviewed.ResultsOf 5254 database patient records, 1150 met our inclusion criteria. Elevated body mass index (BMI), longer procedure duration and a diagnosis of disseminated cancer were associated with post‐operative ICU admission. Prostatectomy and morbid obesity were the most common CPT and ICD‐9 codes identified. Patients who were admitted to the ICU after surgery had a longer hospital length of stay (LOS), had a higher frequency of readmission, re‐operation, and in‐hospital mortality.ConclusionAdmission to the ICU after elective non‐cardiac surgery is common. Our analysis of the ACS NSQIP® database identified elevated BMI, longer duration of surgery and disseminated cancer as predictors of post‐operative ICU admissions in patients undergoing elective non‐cardiac surgery.
Growth Mindsets of Alcoholism Buffer Against Deleterious Effects of Drinking Identity on Problem Drinking Over Time
Authors: Lindgren Kristen P. , Burnette Jeni L. , Hoyt Crystal L. , Peterson Kirsten P. , Neighbors Clayton 
Published: November 2019

BackgroundExplicit (self‐report) and implicit (indirect) measures of identification with drinking alcohol—drinking identity—are associated with drinking outcomes cross‐sectionally and longitudinally. A key next step is to identify moderators. The current study evaluated a promising moderator: mindsets of alcoholism. Believing people can change (growth mindset) is associated with adaptive outcomes in domains such as mental health, but research is scant regarding mindsets related to problematic drinking. We evaluated whether individuals’ alcoholism mindsets moderated the drinking identity to drinking relation as part of a larger, longitudinal web‐based study of heavy drinkers.MethodsA total of 422 US college graduates (59% women) who were heavy drinkers completed measures assessing drinking identity, mindsets, and drinking outcomes (consumption, problems, and risk of alcohol use disorder). Drinking outcomes were assessed at 2 subsequent assessments occurring 4 and 8 months after the initial assessment.ResultsDrinking identity was positively associated with drinking outcomes, and drinking outcomes reduced following college graduation. Alcoholism mindsets were significantly and negatively correlated with all drinking outcomes. Mindsets were only conditionally associated with drinking behaviors over time in models that evaluated mindsets, drinking identity measures, and their interaction. Mindsets moderated the relationship between drinking identity and changes in drinking behaviors, but the relation was specific to explicit drinking identity and consumption. Among participants with stronger drinking identity, those who had stronger (vs. weaker) growth mindsets reported reduction in consumption over time.ConclusionsGrowth mindsets of alcoholism appear adaptive for college graduate heavy drinkers with a stronger drinking identity. Mindsets are amenable to interventions; targeting them may be useful in heavy‐drinking college graduates.
Positive spillover effect and audit quality: a study of cancelling China’s dual audit system
Authors: Zhang Rui , Wong Raymond M. K. , Tian Gaoliang , Fonseka Mohan M. 
Published: November 2019

AbstractThe mandatory dual‐audit and dual‐reporting system (DADRS) for mainland Chinese firms cross‐listed in Hong Kong (AH firms) was abolished in 2010. This study quantifies a positive spillover effect from Hong Kong‐based auditors in the DADRS and examines whether and to what extent this affects the audit quality of AH firms. We find that AH firms exposed to a stronger positive spillover effect have higher audit quality, and the loss of this effect drives the declining audit quality of AH firms after they cancelled the DADRS. This study is among the first empirical works on this research topic.
Identifying Memphis: A comprehensive and comparative description of the immature stages and natural history of Memphis acidalia victoria (H. Druce, 1877; Lepidoptera: Nymphalidae)
Authors: Gueratto Patrícia E , Machado Patrícia A , Aguiar Tamara M C , Barbosa Eduardo P , Dias Fernando M S , Oliveira‐Neto José F , Casagrande Mirna M , Freitas André V L 
Published: November 2019

AbstractMemphis Hübner (1819) is the most species‐rich genus among the Neotropical Charaxinae, occurring from southern United States to Argentina. Memphis acidalia (Hübner, 1819; Anaeini), a common and widespread species distributed in all of South America east of the Andes, is part of a complex of superficially similar, and supposedly related, species with high intraspecific variability. Immature stages are fundamental sources of information for Anaeini taxonomy; however, knowledge on immature stages of Memphis is incomplete. Thus, we describe the immature external morphology, biology and behaviour, plus the chaetotaxy of the first instar of M. acidalia victoria (H. Druce, 1877) and provide distinguishing characteristics of its life stages from those of similar sympatric species, namely. Memphis moruus (Fabricius, 1775), Memphis editha (Comstock, 1961), Memphis philumena (Doubleday, 1849) and Memphis oenomais (Boisduval, 1870). In general, the immature stages are similar to other “moruus‐type'' species of Memphis, differing from other species mostly on the co lour patterns of the fifth instar and pupa.
Application of quantum dot‐based biosensor to the conjunctiva in Wistar albino rats
Authors: Nur İsmail Hakkı , Saçmaci Şerife , Keleş Hacı , Abumandour Mohamed , Testereci Haluk 
Published: November 2019

AbstractThis study was conducted to get an idea about the distribution of the lymphatic fluid in conjunctiva throughout the body parts. For this purpose, Qdot655 (QD), fluorescence nanoparticles, spread onto the conjunctiva were used on Wistar albino rats. Drainage of QD particles from conjunctiva was followed up via fluorescence images at different hours on body parts such as eye, ears, forearms, hind legs and tails. The first fluorescence signals within the 30th minutes following administration of QD were observed in the nasal region and the anterior extremities. Whereas within 60th minutes following QD spread, fluorescent signals were obtained from the ears, forearms, hind legs and tail of the female and male rats.
Editorial: effect of exercise on physical frailty in patients with chronic liver disease
Authors: Ravikiran Sindhuvalada Karnam , Bhat Mamatha 
Published: November 2019

LINKED CONTENTThis article is linked to Williams et al and Armstrong et al papers. To view these articles, visit https://doi.org/10.1111/apt.15491 and https://doi.org/10.1111/apt.15556.
Editorial: evolving histological assessment of NASH. Authors' reply
Authors: Pai Rish K. , Feagan Brian G. , Parker Claire E. , Jairath Vipul , Loomba Rohit 
Published: November 2019

LINKED CONTENTThis article is linked to Pai et al and Rowe papers. To view these articles, visit https://doi.org/10.1111/apt.15503 and https://doi.org/10.1111/apt.15537.
At the intersection of corporate governance and performance in family business settings: Extant knowledge and future research
Authors: Bodolica Virginia , Dupuis Daniel , Spraggon Martin 
Published: November 2019

AbstractDespite the proliferation of research on governance and performance of family firms over the past decades, the extant empirical evidence remains inconclusive. Acknowledging multiple sources of family firm variation, scholars started explaining the observed differences in governance structures and performance outcomes by taking into consideration the heterogeneity among family firms. In this paper, we undertake a review of the literature at the intersection of governance and performance in family firms to elucidate (a) the role of various governance attributes as performance drivers; and (b) the variability of governance effects across different performance indicators. By taking stock of what is already known and discussing avenues for further investigation, we seek to contribute to a more fine‐grained understanding of the intricate governance–performance relationship in light of the heterogeneous nature of family firms. The key priorities for future inquiry consist in: the identification of missing mediating and moderating variables; the inclusion of currently underexplored governance determinants of family firm performance; and the analysis of complementarity and substitution effects among multiple attributes of monitoring and their changing dynamics over time to secure an optimal governance–performance alignment in family firms.
An intelligent optimization‐based traffic information acquirement approach to software‐defined networking
Authors: Huo Liuwei , Jiang Dingde , Lv Zhihan , Singh Surjit 
Published: November 2019

AbstractInternet of things (IoT) is a global information infrastructure that supports access to thousands of monitoring devices and user terminals. A large amount of monitoring data generated by IoT is integrated to cloud computing through the network to improve the quality of life of citizens. Fine‐grained and accurate traffic information is important for IoT network management. Software‐defined networking (SDN) is a centralized control plane as a logical control center, making network management more flexible and efficient. Then, we collect fine‐grained traffic information in SDN‐based IoT networks to improve network management. To acquire the traffic information with low overhead and high accuracy, first, we collect the statistics of coarse‐grained traffic of flows and fine‐grained traffic of links, and then we utilize the intelligent optimization methods to estimate the network traffic. To improve the granularity and accuracy of the acquired traffic information, we construct an optimization function with constraints to decrease the estimation errors. As the optimization function of traffic information is a non‐deterministic polynomial‐hard problem, we present a heuristic algorithm to obtain the optimal solution of the fine‐grained measurement. Finally, we conduct some simulations to verify the proposed measurement scheme. Simulation results show that our approach can improve the granularity and accuracy of traffic information with intelligent optimization methods.
The influence of ink viscosity, water and fabric construction on the quality of ink‐jet printed polyester
Authors: Gao Chengyong , Xing Tieling , Hou Xueni , Chen Guoqiang 
Published: November 2019

AbstractThis paper is concerned with the quality of lines and disperse ink in printing patterns on different untreated polyester fabric constructions. The lines running in the weft and warp directions were printed on polyester fabric constructions, and printing accuracy was assessed. Ink spreading is one of the important factors that influences the ink distribution. Thus, in order to acquire satisfactory ink‐jet printing products, it is essential to control the spreading of ink on the polyester fabric. To meet these conditions, a series of chemicals (disperse dye 5.01 wt%, PVP‐K30 0‐2 wt%, DEG 5‐20 wt%, water 64.17‐79.17 wt%, etc) with different mass fractions was used to prepare disperse ink. The jetting behaviour of ink was related to its surface tension and viscosity, which was characterised by an automatic surface tensiometer and rotational viscometer. Line profile was used to evaluate the printing effect. Low field nuclear magnetic resonance and three‐dimensional super depth digital microscopy were used to reveal the relationships between the state of water, ink diffusion behaviour and printing sharpness. The results showed that increasing ink viscosity or decreasing free water content is advantageous to improve the sharpness of the printing pattern. The effects of fabric structural parameters on line image quality are discussed. The printing quality was closely related to the weight and structure of fabric. The heavy weight fabrics had accurate print pattern sharpness. The fastness test results showed that the ink printing pattern had good colour fastness.
Differential gene expression in fronds and stolons of the siphonous macroalga, Caulerpa lentillifera
Authors: Arimoto Asuka , Nishitsuji Koki , Narisoko Haruhi , Shoguchi Eiichi , Satoh Noriyuki 
Published: November 2019

AbstractThe green alga, Caulerpa lentillifera, is composed of a single cell with multiple nuclei, but it possesses structures analogous to leaves or fronds, stems or stolons, and roots or rhizoids. To understand molecular mechanisms involved in formation and function of these structures, we carried out RNA‐seq analysis of fronds and stolons (including rhizoids). Taking advantage of the decoded genome of C. lentillifera, the present RNA‐seq analysis addressed transcripts corresponding to 9,311 genes identified in the genome. RNA‐seq data suggested that 8,734 genes are expressed in sporophytes. Despite the siphonous body of the alga, differential gene expression was evident in the two structures. 1,027 (11.8%) and 1,129 (12.9%) genes were preferentially expressed in fronds and stolons, respectively, while the remaining 6,578 (75.3%) genes were expressed at the same level in both. Most genes preferentially expressed in fronds are associated with photosynthesis and plant hormone pathways, including abscisic acid signaling. In contrast, those preferentially expressed in stolons are associated with translation and DNA replication. These results indicate that gene expression is regulated differently between fronds and stolons, which probably governs the function of each structure. Together with genomic information, the present transcriptomic data provide genic information about development and physiology of this unique, siphonous organism.
The political economy of trade and migration: Evidence from the U.S. Congress
Authors: Conconi Paola , Facchini Giovanni , Steinhardt Max F. , Zanardi Maurizio 
Published: November 2019

AbstractWe compare the drivers of U.S. congressmen's votes on trade and migration reforms since the 1970s. Standard trade theory suggests that trade reforms that lower barriers to goods from less skilled‐labor abundant countries and migration reforms that lower barriers to low‐skilled migrants should have similar distributional effects, hurting low‐skilled U.S. workers while benefiting high‐skilled workers. In line with this prediction, we find that House members representing more skilled‐labor abundant districts are more likely to support trade and migration reforms that benefit high‐skilled workers. Still, important differences exist: Democrats are less supportive of trade reforms than Republicans, while the opposite is true for migration reforms; welfare state considerations and network effects shape votes on migration, but not on trade.