bluuebunny/crossref_metadata_2025_split huggingface dataset:
Features of lethal cases in patients with TB/HIV co-infection depending on the resistance to antituberculosis agents in the conditions of the antituberculosis dispensary
Authors: Sahaidak Т. К. , Skorokhodova N. О. , Akhtyrskyi О. І. , Fedorets А. V. , Yanovskyi А. V. 
Published: January 2020

Purpose of the study. Analyze lethal cases in patients with the TB/HIV co-infection depending in resistance to anti-TB drugs in the conditions of the antituberculosis dispensary.
Materials and methods. Retrospective analysis was conducted 80 histories and autopsy reports of patients with TB /HIV infection who died in the MI «Zaporizhzhya Regional Anti Tuberculosis Clinical Dispensary» from 2012–2017.
Results. In patients with chemoresistant forms, disseminated tuberculosis was in 36 patients (90%), infiltrative tuberculosis was noted in 2 cases, focal and fibrosis and cavernous – one person each. In the disseminated processes, in addition to the lungs, intranuclear lymph nodes were more often affected – 19 (47,5%), meningoencephalitis – 9 (22,5%), pleurisy –
9 (22,5%), retroperitoneal lymphnodes 2 (5,0%), peripheral lymphnodes – 2 (5,0%), lesions of the spleen – 2 (5,0%), kidneys – 2 (5,0), intestine – 1 (2,5%). In patients with susceptible tuberculosis, pulmonary and extrapulmonary lymph nodes are found in 36 (90.0%), only extrapulmonary – 4 (10,0%). These were pulmonary disseminated processes, including miliary forms. In addition to the lungs, intrathoracic lymph nodes were more often affected in 16 patients (40,0%), in 14 (35,0%) cases there was TB meningoencephalitis, Objective mesenteric lymphnodes – 4 (10,0%), spleen – 3 (7,5%), kidneys – 3 (7,5%), liver – 3 (7,5%), brain tuberculoma –1(2,5%).
Conclusions. Inconducting a comparative analysis of clinical and pathoanatomical diagnoses in patients with susceptible tuberculosis there was only one case in which a patient with brain tuberculoma had not been diagnosed with purulentnecrotizing pneumonia of the upper lobe of the right lung. In patients with resistant forms of tuberculosis in all cases there was a coincidence of diagnoses. The main secondary diagnosis was cryptococcal meningoencephalitis – 8 (20,0%), oncopathology – 2 (5,0%).
BANDS NEUTROPHILS LEVELS CHARACTERIZATION AND THEIR DYNAMICS AT TREATMENT OF ACUTE ALIMENTARY PANCREATITIS PATIENTS
Authors: Avdosiev Y. V. , Pankiv K. M. , Khimich S. D. , Belozоrov I. V. , Kudrevych O. M. , Khytruk S. V. , Ustymenko O. S. , Iaremchuk P. V. 
Published: January 2020

Purpose of the study. To evaluate changes of bands nuclear neutrophils level and their dynamics parameters during treatment in patients with acute alimentary pancreatitis based on repeated measurements and taking into account the severity of the course.
Materials and methods. Seventy patients with acute alimentary pancreatitis were examined, who treated in Surgical Department of Vinnitsa Regional M. I. Pirogov Clinical Hospital. Average age was 45,4 ± 13,87 years. Severe pancreatitis was found in 34 (48,57%) people, in 25 (35,72%) – moderate, 11 (15,71%) persons had mild forms. The severity of the disease was assessed using the Atlanta classification (2012). To achieve aim of study the repeated measurements of the stabs neutrophils levels were performed for all patients. Statistical analysis was performed using STATISTICA 13.
Results. The significant difference between the stabs neutrophils values identified in patients with acute alimentary pancreatitis was proved, taking into account the severity of the course, both during the primary measured (p = 0,04), during treatment (p = 0,004), and after its completion (p < 0,00001). The significant increase of stabs neutrophils level associated with increasing severity of acute pancreatitis, as in the primary treatment of patients (τ = 0,23, p = 0,005), with determination during treatment (τ = 0,31, p = 0,0001) and after its termination (τ = 0,49, p  0,00001) was determined. When comparing the indexes of stabs neutrophils determined by repeated measurements, a rapid and continuous decrease of their values was found, as a whole in the group – by 3,76 times, and in the groups with a mild course of the inflammatory process – 6,75 times, the average degree of severity – in 5,11 times and severe forms – 3,05 times.
Conclusions. Highinformativenessofevaluation stabs neutrophils level and their dynamic during repeated measurements in patients with acute alimentary pancreatitis taking into account the severity of the course has been proved.
THE INCREASED KINETICS OF H2O2-INDUCED CHEMILUMINESCENCE IN THE PATIENTS WITH LONG-TERM CONSEQUENCES AFTER CEREBRAL CONTUSION
Authors: Lekomtseva Y. V. 
Published: January 2020

Purpose of the study. The aim was to study in the patients with long-term consequences after cerebral contusion the intensity of spontaneous and H2O2-induced chemiluminescence in order to evaluate the early fast-flowing reactions caused by oxidative stress and associated with the formation of primary radicals such as free radical oxidations.
Materials and Methods. Forty-two patients with long-term consequences after cerebral contusion were investigated (39,04 ± 12,84 years mean age; mean onset years 32,56 ± 6,4) where both spontaneous and H2O2-induced chemiluminescences were measured directly by HPLC-chemiluminescence assay.
Results. The study have showed that sera of the investigated patients with long-term consequences after cerebral contusion have the increased H2O2-induced chemiluminescence associated with the high amplitude of «fast» burst and the tendency to increase of spontaneous chemiluminescence (p = 0,039 and p = 0,58, accordingly). Thus, the patients with longterm consequences after cerebral contusion showed the abnormal high kinetics of H2O2-induced chemiluminescence (p < 0,05). The statistically significant increase serum Н2О2-induced chemiluminescence intensity detected in examined patients (3085,6 ± 114,2 vs 669,1 ± 214,83 controls) have showed the development of certain oxidative stress processes in this category of patients associated with the increasing of primary free radical reactions and their activity were getting increased with the progression of the disease duration (p < 0,05).
Conclusions. The study provides the novel data revealing the increased kinetics of H2O2-induced chemiluminescence in the patients with long-term consequences after cerebral contusion accompanied by the tendency to increase of spontaneous chemiluminescence that may play the certain pathogenetic role.
Nitric oxide role in development of the endothelial dysfunction in diabetic foot syndrome
Authors: Bilyayeva O. O. , Kozynets H. P. , Osadcha O. I. , Kryzhevskyy Ye. Ye. , Knivets M. A. 
Published: January 2020

Introduction. Diabetes mellitus causes many acute and chronic complications, including diabetic foot syndrome (DFS) – a serious complication that can be a test for patients and directly affect their quality of life.
One of the most effective treatments for DFS is the use of nitric oxide (NO). The main advantage of using NO-therapy is the effect of polyfunctional nitrogen monoxide on all phases of purulent-inflammatory process.
Purpose of the study. The nitric oxide effect features on the development of endothelial dysfunctions in patients with diabetic foot syndrome are explored.
Materials and methods. In the department of purulent surgery at Kyiv City Clinical Hospital No. 6 in 2019 from January to June, 76 patients with DFS in stages II–V were treated by F. Wagner. In 47 (61.8%) patients the neuropathic form of DFS was observed, and 29 (38,2%) were neuroichemic form. According to the DFS rates of F. Wagner patients were distributed: II – 24 (31,7%) patient, III – 29 (38,1%) patient, IV – 15 (19,7%) and V stages – 8 (10,5%). All patients were studied in the capillary zone of necrotic lesions of the content of NO, the activity of superoxide dismutase (SOD).
Results and discussion. The signaling role of NO in cells is highly dependent on the level of superoxide. The balance between systems that synthesize NO and superoxide determines the regulatory orientation of the signals, and its disruption contributes significantly to inflammation in diabetes.
Conclusions. The use of NO-therapy helps to optimize the processes of regulation of the induction of nitric oxide and to improve the clinical results in the treatment of diabetic foot syndrome.
Informatively of histological study by method of mapping ellipticity of polarization of microscopic myocardial images
Authors: Vanchulyak O. Ya. , Lytvynenko O. Yu. , Ushenko O. H. , Andriychuk A. O. 
Published: January 2020

Purpose of the study. To investigate the informational value of the histological examination of the human myocardium in case of sudden cardiac death and the possibility of a method of mapping ellipticity of polarization of microscopic images of the myocardium in the diagnosis and objective differentiation of acute coronary insufficiency (ACI) and chronic coronary heart disease (CIHD).
Materials and methods. Samples of human myocardium from 89 people who died as a result of ACI and CIHD were investigated, using traditional histological and laser polarization techniques, with a standard-scheme laser polarimeter. Subsequently, statistical processing of the obtained results was conducted.
Results. The results obtained show that the values of the statistical moments of the 3rd and 4th order, which characterize the coordinate distributions of the ellipticity of polarization of microscopic images of myocardial samples on the scale of optical magnification ×56, were the most informative for differential diagnosis of ACI and CIHD. Accuracy of ACI and CIHD detection by mapping the ellipticity of polarization of myocardial microscopic images at an optical magnification of ×56 reaches ~ 97%, as opposed to the traditional histological examination ~ 81%.
Conclusion. On the basis of the obtained data, we confirm the diagnostic efficiency and accuracy of the method of mapping the values of ellipticity polarization of microscopic images of histological sections of the myocardium in the problem of diagnosis and objective differentiation of ACI and CIHD.
Three-dimensional spatial reconstruction of the gunshot injuries in the practice of forensic medicine
Authors: Bachynskyy V. T. , Zmiyevska Y. H. , Savka I. H. 
Published: January 2020

During the recent years the number of the wounded and killed due to firearms use both in Ukraine and in the majority of the world countries has increased. Therefore, examination of gunshot injuries is rather topical issue now in forensic medicine, and it is a considerable comprehensive question.Transience of incidences with the use of firearms in the majority of cases does not enable to find a real picture of circumstances when these incidences occur. Therefore, the issues of traumatic factor identification in these cases, especially with perforating and tangential injuries, are very important in forensic medicine, but remain elucidated insufficiently.
At the same time, a dynamic development of upto-date computer technologies enables to increase the level of visualization, forensic diagnostics of injuries and substantiation of expert conclusions in case of gunshot injuries.
Purpose of the study. To study diagnostic possibilities of three-dimensional spatial reconstruction method for forensic identification of the main traumatic factor in case of gunshot injuries.
Materials and methods. Ballistic plasticine and gel, fragments of pig skin with subcutaneous fat, fragments of biological tissues with gunshot injuries were used as the material for the study. The obtained experimental gunshot injuries (45 cases) and cases of injuries from the expert practice (30 cases) were subjected to photogrammetric with possibility to obtain a three-dimensional spatial model of every injury by means of the computer program Agisoft Photoscan.
Results. The studies conducted differ from the existing ones by their novelty, higher inventive and scientific-practical level. Three-dimensional spatial digital models of the injured biological tissues and their imitators will be designed, examined and analyzed for the first time, and the diagnostic criteria for forensic identification of the main traumatic factor of gunshot body injuries will be developed. The obtained textured models of gunshot injuries in «Obj» format can be imported into the program 3dsMax, which enables to examine linear sizes of every fragment of a wound canal with higher accuracy (to 0,001 cm) in comparison with classical methods of examination.
The results obtained while conducting the study enable not only to develop computer threedimensional digital models of gunshot body injuries, but examine their character and morphologic peculiarities in forensic practice on an up-to-date scientific level. All the mentioned above enables to formulate and substantiate new, more accurate forensic diagnostic identification criteria of the main traumatic factor of gunshot body injuries.
Conclusion. Introduction of up-to date computer technologies into the practice of forensic medicine will enable to determine identifying peculiarities of the main traumatic factor in case of gunshot injuries with a higher accuracy.
Traumatic disease peculiarities course, its diagnostics and treatment at polytrauma in suffer obese patients
Authors: Khimich S. D. , Chemerys O. M. 
Published: January 2020

Introduction. It’s known that the issue of polytrauma is one of the most urgent problems of surgery, and among injured patients a special approach is required for patients with overweight and obesity of varying degrees.
Purpose of the study. To study prognostic features of traumatic disease course and to improve the results of diagnostics and surgical treatment of patients with polytrauma suffer obesity.
Materials and methods. Clinical material was made up of 106 patients with combined body trauma, which were divided into three groups according to body mass index.
Results. The results of the research showed a significant difference in the course of traumatic disease in patients with normal body weight and obesity. In particular, in the process of diagnostics of blunt chest and abdominal trauma the frequency of application of interventional methods of diagnostics was directly proportional to the increase of body mass index. The course of traumatic disease in the obese patients had a number of characteristic features that formed the basis for the development of diagnostics and differential program of treatment.
Conclusions. The results of the research showed that the course of traumatic disease in combined injury obese patients is directly proportional to the body mass index and has certain features that differentiate them from patients with normal body weight.
السلطة في العمارة والنقد المعماري
Authors: Abbas Sana Sati , Al-Dahui Suha Hassan 
Published: January 2020

ركزت العديد من الدراسات المختصة بموضوع النقد على مفهوم السلطة وتباينت هذه الدراسات في مقاصدها حول نوع تلك السلطة تبعا لتوجهاتها في النظرية النقدية كما تباينت في مجال اهتمامها من الاهتمام بالمؤلف ثم الانصراف التام الى النص.وأخيرا تحول الانتباه الى القارئ في العقود الأخيرة من القرن العشرين . تمثلت مشكلة البحث بعدم وجود تصور شامل لمفهوم السلطة في العمارة والنقد المعماري الأكاديمي بشكل خاص.إذ يهدف البحث الى تحديد خصوصية مفيوم السلطة في العمارة والنقد المعماري كما يفترض البحث أن السلطة في العمارة تلاؤمية متعددة المصادر والمعاني والوسائل ومجالات الظهور وتبرز بشكل كبير في النص المعروض للنقد من خلال مفردات خارجية تعبر عن روح العصر والقواعد الفنية . وقد استد منهج البحث على (دراسة نظرية تم فيها تحديد إطار نظري لمفهوم السلطة في العمارة والند المعماري بشكل عام ودراسة عملية تم فيها استبيان مجموعة من النقاد الأكاديميين حول مفردات ذلك الإطار، ومن ثم تم تحليل النتائج للوصول الى الاستنتاجات المعبرة عن الخصوصية العراقية لمفهوم السلطة في العمارة والنقد لدى النقاد الأكاديميين ).
وقد استنتج البحث ( السلطة في العمارة والنقد تلاؤمية.مصدرها النص وتشمل العديد من المعاني أبرزها الابداع والتأثير والتفوق وتبرز السلطة في مجال المعارض الخاصة بعرض للنتاجات الخاصة بالمسابقات (المحلية والعالمية ) ونتاج الطلبة . وتستد السلطة في النقد الى بعض الوسائل أبرز ها الحث الدائم للمصمم وإعطاء التقديرات والإيضاح لخلق نتاجات تستجيب لروح العصر ومن خلال التعامل مع العملية التصميمية والسياق المتبع في التصميم .
KORELASI DURASI PENGGUNAAN KONTRASEPSI ORAL DAN STADIUM KANKER SERVIKS DI RSUD ARIFIN ACHMAD PROVINSI RIAU
Authors: Utomo Feriandri , Afandi Ahmad , Rivai Syamsul Bahri 
Published: January 2020

Insidensi kanker serviks terus meningkat, termasuk di RSUD Arifin Achmad Provinsi Riau, di mana terjadi hampir 8 kali peningkatan insidensi kanker serviks pada tahun 2017 dibandingkan pada tahun 2016. Penggunaan kontrasepsi oral yang menjadi salah satu faktor risiko kanker serviks, juga mengalami peningkatan drastis di Provinsi Riau. Durasi penggunaan kontrasepsi oral terbukti berhubungan signifikan terhadap peningkatan risiko Cervical Intraepithelial Neoplasia grade 3 (CIN3). Penelitian ini bertujuan untuk menganalisis hubungan antara durasi penggunaan kontrasepsi oral dengan stadium kanker serviks. Penelitian ini merupakan penelitian analitik observasional, dengan rancangan cross sectional. Pengambilan sampel dilakukan dengan teknik total sampling pada data rekam medis pasien selama tahun 2017 di RSUD Arifin Achmad Provinsi Riau dan diuji secara statistik menggunakan uji korelasi Spearman Rank. Penelitian ini menemukan terdapat korelasi kuat yang signifikan antara durasi penggunaan kontrasepsi oral dengan stadium kanker serviks (p-value < 0,05 dan r = 0,74). Selain itu, durasi penggunaan kontrasepsi oral berpengaruh terhadap peningkatan stadium kanker serviks sebesar 54,7% (r2 = 0,547). Dari penelitian ini dapat disimpulkan bahwa durasi penggunaan konstrasepsi oral sangat berhubungan dengan peningkatan stadium kanker serviks.
COMPARISON OF PATCHING DURATION ON AMBLYOPIC CHILDREN IN CMH MUZAFFARABAD
Authors: Malik Sidra , Zaib Iqra , Farooq Omer , Hanif Kanwal 
Published: January 2020

Objective: To Compare the efficacy of 2 different patching regimens in amblyopic children and highlight the factors affecting compliance.
Materials & Methods: The randomized control trial was conducted in Eye OPD SKBZ Hospital Muzaffarabad from September 2017- March 2018. Analysis was limited to children 4 to 16 years of age with unilateral amblyopia. Personal information, visual acuity with and without correction, Cycloplegic refraction & subjective refraction was noted. Children with amblyopic eye acuity of 20/40 to 20/200 (mean 0.56 log MAR, approximately 20/63) and inter ocular acuity difference of 2 or more lines were specified to get either 2 hours (Group A) or 6 hours (Group B) of daily patching, combined with 1 hour of near visual activities per day. Follow up period was 2 weeks, 4 weeks and 3 months.
Results:
Out of 72 children 44(61.1%) were males and 28(38.9%) were females. The mean age was 10.25 ± 0.67 years. Mean visual acuity was 20/63(+0.5 log Mar) in both groups. In group A, 66.7 % and in group B 83.3% of patients showed improvement. The mean difference of BCVA was 2.77 ± 1.28 SD and 3.41±3.16 SD in group ‘A’ and group ‘B’ respectively. Group A and B showed improvement of 3.0 and 2.0 lines respectively. Both groups showed a poor compliance of 11.2 %.
Conclusion:
2 hours of patching along with 1 hour of near activity is sufficient to treat amblyopia as compared to 6 hours of patching. Firstly, screening should be done to diagnose amblyopia at early stage. Secondly compliance is found to be a single most important factor to improve outcomes.
Hubungan Status Pekerjaan Ibu Dengan Status Gizi Balita
Authors: Fauzia Nenes Riana , Sukmandari Ni Made Ari , Triana Komang Yogi 
Published: January 2020

Status gizi balita sangat berhubungan dengan faktor ekonomi. Sementara itu kondisi ekonomi keluarga tergantung dari pekerjaan kedua orang tuanya. Ibu yang bekerja memiliki waktu yang lebih sedikit untuk mengurus anaknya sehingga akan berpengaruh pada kualitas perawatan balita sehingga mempengaruhi status gizi balita. Tujuan penelitian ini untuk mengetahui Hubungan Status Pekerjaan Ibu dengan Status Gizi Pada Anak Balita di Wilayah Kerja UPT Puskesmas Kuta Utara Tahun 2018. Penelitian ini menggunakan desain cross sectional dengan jumlah sampel 61 orang ibu bekerja yang dipilih melalui teknik purposive sampling dengan menggunakan kriteria inklusi dan ekslusi. Uji statistik yang digunakan yaitu Spearman Rank (p value <p, p =0,05). Hasil uji univariat menunjukkan bahwa frekuensi ibu bekerja sebanyak 35 responden (55,7%), frekuensi status gizi balita terbanyak adalah kategori normal sebanyak 44 responen (72,1%). Hasil uji bivariat diperoleh p value = 0,001 < 0,05, maka dapat disimpulkan bahwa ada hubungan yang signifikan antara status pekerjaan ibu dengan status gizi balita di Wilayah Kerja Upt Puskesmas Kuta Utara. Berdasarkan hasil penelitian tersebut diharapkan perawat dapat mengedukasi para ibu untuk dapat membagi atau mengatur waktunya dalam pekerjaan sehingga dapat memperhatikan status gizi anak balitanya.
O kulawym bogu Hefajstosie. W antycznej pracowni Jana Dormana
Authors: Biernat Justyna 
Published: January 2020

The paper is an analysis of Jan Dorman’s theatre practice in the context of the classical tradition. It examines the archival collections of The Theatre Institute documenting the collaboration of Jan Dorman with Anna Świrszczyńska on the staging of O kulawym bogu Hefajstosie (“The Lame God Hephaestus”), Świrszczyńska’s radio play. The extant correspondence between the creators of the production and the director’s copies permit us to explore and analyse the ways in which classical antiquity inspired Dorman’s work. Although Dorman never adapted any ancient Greek text to the stage, his practice indicates a strong presence of the classical tradition, in particular the Greek comedy, in his mode of theatre.
ОСОБЛИВОСТІ ДОСЛІДЖЕННЯ 3,4-МЕТИЛЕНДІОКСИПІРОВАЛЕРОНУ ТА РОЗРІЗНЕННЯ МОЖЛИВИХ ЙОГО СУМІШЕЙ ІЗ МЕТАДОНОМ І КОКАЇНОМ
Authors: П. О. Зелений О. С. Зав’ялов, 
Published: January 2020

Окреслено особливості дослідження 3,4-метилендіоксипіровалерону за допомогою якісних хімічних реакцій, тонкошарової хроматографії, газорідинної хроматографії з мас-селективним і полум’яно-іонізаційним детектуванням, рідинної хроматографії з мас-спектрометричним детектуванням. Уточнено його загальну характеристику, фізичні та хімічні властивості; акцентовано увагу на відмінностях 3,4-метилендіоксипіровалерону, метадону та кокаїну під час дослідження методами якісних хімічних реакцій і тонкошарової хроматографії. Обґрунтовано результати експериментальних даних щодо зміни забарвлення під час якісних хімічних реакцій трьох речовин із сімома реагентами. Виокремлено результати проведення двох реакцій щодо ідентифікації метадону і трьох –щодо визначення кокаїну. Засвідчено характерну особливість 3,4-метилендіоксипіровалерону, що проявляється на пластині для тонкошарової хроматографії в ультрафіолетовому світлі (254 і 366 нм) та дає змогу висунути припущення стосовно можливих речовин. Висвітлено результати експериментальних даних хроматографування в чотирьох системах для тонкошарової хроматографії, що дозволяють отримати максимальну різницю значень Rf між метадоном, кокаїном та 3,4-метилендіоксипіровалероном.Ключові слова: 3,4-метилендіоксипіровалерон; метадон; кокаїн; якісні хімічні реакції; тонкошарова хроматографія; газорідинна хроматографія; рідинна хроматографія.