bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single-position prone lateral approach: cadaveric feasibility study and early clinical experience
Authors: Godzik Jakub , Ohiorhenuan Ifije E. , Xu David S. , de Andrada Pereira Bernardo , Walker Corey T. , Whiting Alexander C. , Turner Jay D. , Uribe Juan S. 
Published: September 2020

OBJECTIVELateral lumbar interbody fusion (LLIF) is a useful minimally invasive technique for achieving anterior interbody fusion and preserving or restoring lumbar lordosis. However, achieving circumferential fusion via posterior instrumentation after an LLIF can be challenging, requiring either repositioning the patient or placing pedicle screws in the lateral position. Here, the authors explore an alternative single-position approach: LLIF in the prone lateral (PL) position.METHODSA cadaveric feasibility study was performed using 2 human cadaveric specimens. A retrospective 2-center early clinical series was performed for patients who had undergone a minimally invasive lateral procedure in the prone position between August 2019 and March 2020. Case duration, retractor time, electrophysiological thresholds, implant size, screw accuracy, and complications were recorded. Early postoperative radiographic outcomes were reported.RESULTSA PL LLIF was successfully performed in 2 cadavers without causing injury to a vessel or the bowel. No intraoperative subsidence was observed. In the clinical series, 12 patients underwent attempted PL surgery, although 1 case was converted to standard lateral positioning. Thus, 11 patients successfully underwent PL LLIF (89%) across 14 levels: L2–3 (2 of 14 [14%]), L3–4 (6 of 14 [43%]), and L4–5 (6 of 14 [43%]). For the 11 PL patients, the mean (± SD) age was 61 ± 16 years, mean BMI was 25.8 ± 4.8, and mean retractor time per level was 15 ± 6 minutes with the longest retractor time at L2–3 and the shortest at L4–5. No intraoperative subsidence was noted on routine postoperative imaging.CONCLUSIONSPerforming single-position lateral transpsoas interbody fusion with the patient prone is anatomically feasible, and in an early clinical experience, it appeared safe and reproducible. Prone positioning for a lateral approach presents an exciting opportunity for streamlining surgical access to the lumbar spine and facilitating more efficient surgical solutions with potential clinical and economic advantages.
Back pain outcomes after minimally invasive anterior lumbar interbody fusion: a systematic review
Authors: Chan Alvin Y. , Lien Brian V. , Choi Elliot H. , Chan Andrew K. , Hanna George , Lopez Alexander M. , Brown Nolan J. , Gattas Sandra , Kirillova Lydia , Horton David , Fote Gianna , Hanst Brian , Perry Ryan , Lee Yu-Po , Golshani Kiarash , Hsu Frank P. K. , Oh Michael Y. 
Published: September 2020

OBJECTIVEMinimally invasive anterior lumbar interbody fusion surgery (MIS ALIF) is a technique that restores disc height and lumbar lordosis through a smaller exposure and less soft-tissue trauma compared to open approaches. The mini-open and laparoscopic assistance techniques are two main forms of MIS ALIF. The authors conducted a systematic review that sought to critically summarize the literature on back pain following MIS ALIF.METHODSIn March 2020, the authors searched the PubMed, Web of Science, and Cochrane Library databases for studies describing back pain visual analog scale (VAS) outcomes after MIS ALIF. The following exclusion criteria were applied to studies evaluated in full text: 1) the study included fewer than 20 patients, 2) the mean follow-up duration was shorter than 12 months, 3) the study did not report back pain VAS score as an outcome measure, and 4) MIS ALIF was not studied specifically. The methodology for the included studies were evaluated for potential biases and assigned a level of evidence.RESULTSThere were a total of 552 patients included from 13 studies. The most common biases were selection and interviewer bias. The majority of studies were retrospective. The mean sample size was 42.3 patients. The mean follow-up duration was approximately 41.8 months. The mean postoperative VAS reduction was 5.1 points. The mean VAS reduction for standalone grafts was 5.9 points, and 5.0 points for those augmented with posterior fixation. The most common complications included bladder or urinary dysfunction, infection, and hardware-related complications.CONCLUSIONSThis was a systematic review of back pain outcomes following MIS ALIF. Back pain VAS score was reduced postoperatively across all studies. The complication rates were low overall. MIS ALIF is safe and effective at reducing back pain in appropriate patient populations.
Keadilan Spasial Dan Keseimbangan Kebutuhan Lokal Dalam Neo-Endogenous Model Pembangunan Pedesaan Di Desa Koto Mesjid, Kecamatan XIII Koto Kampar, Kabupaten Kampar
Authors: Bunga Chintia Utami  , Putri Asrina  
Published: September 2020

Indeks pembangunan desa mengukur perkembangan kemandirian Desa berdasarkan implementasi terhadap Undang-Undang Desa. Kemandirin desa penting dilakukan untuk mendorong pembangunan. Hasil survey Potensi Desa (Podes) 2018 menunjukkan 87,43 persen desa di Riau adalah Desa Berkembang, 7,09 persen Desa Mandiri dan 5,48 persen adalah Desa tertinggal. Salah satu masalah dalam pembangunan desa adalah tidak sesuainya antara karakteristik dan potensi desa dengan kebijakan pembangunan yang dilakukan. Olehkarena itu perlu dilakukan identifikasi model pembangunan desa untuk dapat mengetahui kebijakan pembangunan yang tepat. Tujuan penelitian ini untuk melihat model neo-endogenous dalam pembangunan pedesaan di desa Koto Mesjid serta upaya pemerintah desa dalam membentuk karakteristik masyarakat dalam model neo-endogenous. Penelitian dilakukan pada desa Koto Mesjid Kabupaten Kampar dengan metode kualitatif diskriftif dan dibantu aplikasi nvivo plus 12 untuk memudahkan pengkodeaan dan menganalisis data kualitatif.
Pembangunan Berbasis Masyarakat Di Kecamatan Kampar Kabupaten Kampar
Authors: Surya Dailiati  , Hernimawati  , Sudaryanto  
Published: September 2020

Kabupaten Kampar merupakan salah satu kabupaten yang ada di Provinsi Riau. Kabupaten ini termasuk daerah yang memiliki wilayah yang sangat luas di bandingkan dengan kabupaten/kota lainnya di Provinis Riau. Terbukti sejak era resformasi dari Kabupaten Kampar telah berhasil di mekarkan sejumlah daerah yakni Kabupaten Rokan Hulu, Kabupaten Pelalawan dan sebagian Kabupaten Kuantan Singingi serta sebagian Kabupaten Rokan Hilir. Dari pengamatan yang dilakukan ternyata di Kecamatan Kampar Kabupaten Kampar terdapat permasalahan yang perlu diselesaikan yakni terdapat madrasyah yang digunakan untuk siswa belajar dalam keadaan kurang layak dimana dinding dan atapnya rusak. Kemudian lapangan sepak bola yang kurang terawat sehingga bersemak dan hutan lindung yang belum terkelola dengan baik sesuai dengan kearifan lokal. Oleh karena itu dilakukan penelitian, untuk pemecahan masalahnya menggunakan teori Tim Delivery dalam Aprillia Theresia dkk (2014 halaman 220). Pembangunan berbasis masyarakat mencakup; seleksi lokasi, sosialiasi, proses dan pemandirian masyarakat. Dari kegiatan penelitian yang dilakukan diketahui bahwa pembangunan berbasis masyarakat di Kecamatan Kampar Kabupaten Kampar sudah berjalan dengan namun masih diperlukan perbaikan-perbaikan. Hal-hal yang sudah berjalan dengan meliputi seleksi lokasi, sosialisasi pembangunan berbasis masyarakat dan proses pembangunan berbasis masyarakat. Sedangkan yang perlu menjadi perbaikan kedepannya adalah pemandirian masyarakat
Schutzwälder gegen Rutschungen: Ausscheidung und Pflege als Verbundaufgabe
Authors: Lange Benjamin , Losey Stéphane , Sandri Arthur 
Published: September 2020

Protection forests against landslides: delimitation and maintenance as a joint task
Landslides are natural hazards that occur frequently and are decisively involved in water-relevant hazards such as debris flows, driftwood and overbank sedimentation. Protection against natural hazards is a joint task of the Confederation, the cantons and third parties. As a measure of integrated risk management, the cantons delimitate protection forests against shallow landslides based on principles developed jointly with the Confederation. In relation to the total area of protection forests in Switzerland, landslides are the most frequent natural hazard against which forests protect. The enforcement aid «Sustainability and Success Monitoring in Protection Forests (NaiS)» defines binding silvicultural targets for protection forests. In recent years, various research institutions have looked more closely at the impact of forests on slope movements. The «torrent, flood» requirement profile of NaiS is currently being revised at the Federal Office for the Environment. In the channel slopes, the goal is to shift the emphasis to protection against landslides. This requirement profile will be designed in accordance with the current state of knowledge. In doing so, no fundamental changes to the existing profile will be necessary. ProtectBio defines a procedure, which enables the assessment of risk reduction through protective forest for shallow landslides to be in compliance with risk reduction through technical protective measures.
Föderaler Vollzug der Schweizer Waldpolitik – ein Erfolgsmodell?
Authors: Walker David , Abt Thomas 
Published: September 2020

Federal implementation of Swiss forest policy – a success story?
Forest policy is considered a joint responsibility between the Confederation and the cantons. The Federal Constitution lays the foundations for the cooperation between the two levels (sovereignty of the cantons, subsidiarity, cooperation based on partnership). Vertical and horizontal institutions have emerged for the necessary processes of exchange in the federal system. In the context of the implementation of the new system of financial equalisation and allocation of tasks between the Confederation and the cantons (NFA), the joint responsibility for forest policy is regularly called into question. Forest policy can be used as an example to show what the characteristics, advantages and disadvantages of implementation in a federal system are. From the point of view of forest policy actors, federal implementation can certainly be described as a successful model. However, the model has potential for improvement. First, the involvement of the cantons in federal processes can be optimised. Second, the positive aspects should be put into perspective because certain forest policy goals have not been achieved for decades.
HUBUNGAN PERAWATAN INFUS DENGAN KEJADIAN FLEBITIS PADA PASIEN RAWAT INAP DI RUANG MAWAR RSUD Dr. HARJONO KABUPATEN PONOROGO
Authors: Andriani Detik 
Published: September 2020

Pemasangan infus sebagai salah satu tindakan invasif memerlukan keterampilan yang cukup saat melakukan pemasangannya. Flebitis adalah peradangan pada dinding pembuluh darah balik atau vena. Tujuan penelitian ini untuk mengetahui hubungan perawatan infus dengan kejadian flebitis pada pasien rawat inap di ruang Mawar RSUD Dr. Harjono Kabupaten Ponorogo.
Desain penelitian studi korelasional. Jenis penelitian ini kuantitatif dengan metode observasional dan wawancara. Sampel peneliatian 10 perawat yang ada di ruang Mawar RSUD Dr. Harjono Ponorogo dan 30 pasien yang ada di ruang Mawar. Teknik sampling menggunakan accidental sampling dengan Uji Chi Square p value=0,01 (p<0,05).
Data hasil penelitian yaitu Pasien yang mengalami flebitis sebanyak 12 responden (40%) dan tidak mengalami flebitis 18 responden (60%) dikarenakan perawatan infus yang kurang sebesar 17 responden (57%), sebanyak 13 responden (43%) dalam kategori baik dan responden dengan kategori baik sekali sebanyak 0 responden (0%) di Ruang Mawar RSUD Dr. Harjono Ponorogo.
Berdasarkan hasil penelitian ini dapat dijadikan bahan pertimbangan dalam menentukan kebijakan berupa pengadaan acuan atau pedoman perawatan infus RSUD Dr. Harjono Ponorogo
Pemberian Konsentrasi Pupuk Pelengkap Cair (Ppc) Terhadap Pertumbuhan Beberapa Genotip Krisan Hasil Poliploidi
Authors: Assafaat Hadi Roni 
Published: September 2020

Penelitian ini bertujuan untuk mengetahui pengaruh pupuk pelengkap cair terhadap pertumbuhan dan hasil beberapa genotip krisan hasil poliploid. Penelitian ini dilaksanakan di rumah kaca Fakultas Pertanian Universitas Winaya Mukti, dari bulan Juni sampai dengan bulan September 2018 dengan ketinggian tempat 878 meter di atas permukaan laut(m dpl). Rancangan percobaan yang digunakan adalah Rancangan Petak Terbagi (Split Plot Design)yang terdiri dari 2 faktor dan 2 ulangan. Faktor pertama adalah konsentrasi PPC (P) ditempatkan sebagai petak utama yang terdiri dari 5 taraf yaitu : p0 = Tanpa PPC, p1 = PPC 1 ml L-1 larutan, p2 = PPC 2 ml L-1 larutan, p3 = PPC 3 ml L-1 larutan, p4 = PPC 4 ml L-1 larutan. Faktor kedua adalah genotip krisan hasil poliploidi (G) ditempatkan sebagai anak petak yang terdiri atas 4 taraf yaitu : g0 = KRA0, g1 = KRA1, g2 = KRA2, dan g3 = KRA3. Hasil percobaan ini menunjukan bahwa terjadi interaksi antara konsentrasi pupuk pelengkap cair dan genotip krisan KRA0,KRA1,KRA2,KRA3 pada tinggi tanaman umur 12 MST, diameter batang umur 2 MST. Pengaruh konsentrasi pupuk pelengkap cair pada genotip krisan hasil poliploidi menunjukkan pengaruh yang lebih baik terhadap tinggi tanaman pada umur 12 MST, diameter batang 2 MST, 10 MST, dan 12 MST, jumlah daun per tanaman pada umur 10 MST dan 12 MST. Berdasarkan hasil percobaan dan analisis ditemukan bahwa PPC 3 ml L-1 berpengaruh terhadap genotip krisan hasil poliploidi KRA1 yang memberikan pertumbuhan genotip krisan hasil poliploidi terbaik.
EFEKTIVITAS PUPUK KANDANG BERBASIS KOMPOS Azolla microphylla DAN PEMAKAIAN PUPUK NPK TERHADAP PERTUMBUHAN SERTA HASIL TOMAT CHERRY
Authors: Devi Laksitarani Swadea , Dewanto Eko , Rokhminarsi Eni 
Published: September 2020

Tomat cherry (Lycopersicum esculentum var. ceraciforme) merupakan salah satu komoditas pertanian unggulan yang dianggap mempunyai prospek baik dalam pemasarannya. Rasanya yang manis dan segar serta kandungan gizi yang baik untuk tubuh dan penyembuhan beberapa penyakit membuat permintaan tomat cherry semakin meningkat. Dewasa ini dalam dunia pertanian, untuk meningkatkan hasil panen petani banyak menggunakan pupuk sintetis sehingga membuat lingkungan tercemar. Berbagai formulasi bahan alami sudah banyak digunakan di dunia pertanian saat ini, seperti pupuk kandang yang dicampur dengan kompos Azolla microphylla. Penggunaan pupuk kandang dan kompos Azolla microphylla diharapkan dapat mengurangi penggunaan pupuk sintetis seperti pupuk NPK. Penelitian ini bertujuan untuk 1) mengetahui pengaruh penggunaan pupuk kandang berbasis kompos Azolla microphylla dan pupuk NPK terhadap pertumbuhan dan hasil tanaman tomat cherry, 2) mengetahui pengaruh penggunaan pupuk kandang berbasis kompos Azolla microphylla dan pupuk NPK terhadap efisiensi penggunaan pupuk NPK pada tanaman tomat cherry. Penelitian dilaksanakan di screen house Universitas Jenderal Soedirman, Purwokerto dengan ketinggian 110 m dpl. Penelitian dilaksanakan selama 3 bulan 21 hari mulai bulan Juli sampai November 2014. Rancangan yang digunakan adalah Rancangan Acak Kelompok (RAK) pola faktorial dengan 2 faktor masingmasing 3 perlakuan dengan 3 ulangan. Faktor pertama adalah formulasi pupuk kandang berbasis kompos Azolla microphylla yang terdiri dari K1 (100% pupuk kandang), K2 (75% pupuk kandang dan 25% kompos Azolla microphylla), dan K2 (50% pupuk kandang dan 50% kompos Azolla microphylla). Faktor kedua adalah dosis pupuk NPK, yaitu D0 (100% dosis rekomendasi), D1 (75% dosis rekomendasi), dan D2 (50% dosis rekomendasi) dengan dosis rekomendasi yang digunakan sebanyak 10 g/tanaman. Analisis data menggunakan uji F dengan taraf kesalahan 5%, apabila berpengaruh nyata dilanjutkan dengan uji DMRT dengan taraf kesalahan 5%. Variabel yang diamati adalah tinggi tanaman, diameter batang, jumlah daun, jumlah cabang, bobot tanaman segar, bobot tanaman kering, bobot akar segar, bobot akar kering, jumlah bunga total, jumlah buah per tanaman, bobot buah per tanaman, volume tiap buah, serta Efisiensi Penggunaan Pupuk (EPP). Hasil penelitian menunjukkan bahwa perlakuan pupuk kandang berbasis kompos Azolla microphylla dan pupuk NPK menurunkan diameter batang, jumlah cabang, jumlah daun, dan jumlah bunga per tanaman, namun pemberian kompos Azolla microphylla sebesar 25% dengan penurunan dosis pupuk NPK sebesar 50% meningkatkan bobot tanaman kering sebesar 0,89% dan meningkatkan efisiensi penggunaan pupuk sebesar 25,76%.
KEEFEKTIFAN BAKTERI Serratia ENDOSIMBION WBC TERHADAP LALAT BUAH MELON (Bactrocera cucurbitae)
Authors: Astriani Maya , Rostaman  , Ismangil  
Published: September 2020

Lalat buah (Bactrocera spp.) merupakan salah satu hama penting pada tanaman buah-buahan dan sayuran di Indonesia. Hama ini bersifat polifag, menyerang berbagai jenis tanaman demi kelangsungan hidupnya. Di alam, bakteri Serratia mengakibatkan kematian wereng batang coklat. Penelitian ini bertujuan untuk: 1) mengetahui keefektifan bakteri Serratia Endosimbion WBC berdasarkan mortalitas lalat buah Bactrocera cucurbitae, 2) memastikan penularan bakteri tersebut secara transovarial, 3) mengetahui abnormalitas imago keturunan pertama (G1) akibat perlakuan bakteri tersebut. Penelitian ini dilaksanakan pada bulan Maret – Juni 2014 di BBPOPT Jatisari, Karawang dengan rancangan percobaan. Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 5 ulangan. Perlakuan tersebut antara lain: 1) Kontrol atau tanpa Bakteri Serratia (B0), 2) B1 : 3,09 x 1046 sel/mL bakteri Serratia, 3) B2 : 2,16 x 1052 sel/mL bakteri Serratia, 4) B3 : 1,73 x 1061 sel/mL bakteri Serratia, 5) B4 : 4,5 x 1066 sel/mL bakteri Serratia. Data dianalisis menggunakan ANOVA dan dilanjutkan dengan DMRT. Hasil penelitian mengungkapkan mortalitas imago sangat rendah yaitu 4 %, bakteri bersifat transovarial, tidak mengakibatkan abnormalitas imago keturunan pertama. Bakteri ini belum dapat digunakan sebagai agen pengendali hayati lalat buah yang potensial.
Ultrafine Bubble Water Usefulness in Fecal Microbiota Transplantation: Recognition of Transplanted Microbiota in Intestinal Epithelial Cells
Authors: Shimizu Shin , Dan Katsuaki , Tanaka Chihiro , Tanaka Mikiko , Tanaka Yoshimu , Shirotani Masahiko , Kitamura Kunihiro , Yorozu Kensho , Oehorumu Masayuki , Tsukamoto Goro 
Published: September 2020

Background: Indications for various diseases such as diabetes mellitus and metabolic syndrome, etc. of Fecal Microbiota Transplantation (FMT) have been investigated. For the establishment of the FMT therapy, the examination of the solvent has not been carried out, though the use of the physiological saline is fixed, at present. We have produced the Mr. Shimizu made ultrafine bubble water (UFB) that produces a larger number of bubbles than existing UFB.Objective: To verify the usefulness of UFB, we prepared a conventional Saline and UFB-prepared microbial preparation (Bio3); (Bio3/Saline) and (Bio3/UFB). The bacterial preparations, Bio3, contain glycated bacteria, lactic acid bacteria, and butyric acid bacteria. FMT was carried out to the diabetic model mouse using these microbial preparations, and whether the disease state was improved was examined. Cultured intestinal epithelial cells (CaCO-2) were also used to test for differentiation by UFB and Saline from variations in several receptors that recognize microbiota-mRNA. In addition, glucose uptake into cells was measured.Methods: FMT with (Bio3/UFB) and (Bio3/Saline) was performed in streptozotocin-induced diabetic mice (STZ-mice) in duplicate at 0, 7 days. Blood glucose levels (7, 14 days) and blood insulin levels (14 days) were measured. Cultured intestinal epithelial cells were also used to test for differentiation by UFB and Saline from change in several receptors that recognize microbiota-mRNA (Toll-like receptors, NOD-like receptors, and RIG-I-like receptors). In addition, glucose uptake into cells was measured using fluorescently labeled glucose analog (NBDG).Results: UFB could reduce the blood glucose level of STZ-induced diabetic model mice. However, no such effects were observed in Saline. Stimulation of serially diluted Bio3 with UFB-suspension were showed significant alteration in TLR4 and IL-1B-uPNA. The amount of glucose uptake in the (Bio3/UFB) group was significantly different at 30 min, inhibited or delayed. Conclusion: It is concluded that UFB-mediated cross-talk between intestinal bacteria and intestinal epithelial cells and inhibition or delay of intestinal epithelial glucose uptake may have been associated with the reduction of blood glucose levels in diabetic model mice. The superiority of UFB as a suspension used for the transfer of bacteria has been suggested.
Expression levels of ABCG2 and CD61 genes in breast cancer tissues of Iranian population
Authors: Liaghati Pegah , Momeni Parto , Oskooei Vahid Kholghi , Ghafouri-Fard Soudeh , Taheri Mohammad 
Published: September 2020

Breast cancer as the most common female cancer is a malignancy with heterogeneous course. Dysregulation of several genes has been associated with development of this malignancy. Among these genes are the stem cell markers CD61 and breast cancer resistance protein (BCRP or ATP-binding cassette super-family G member 2 (ABCG2)). ABCG2 is one of the major efflux transporters implicated in multidrug resistance in cancer cells. In the present study, we compared expression of CD61 and ABCG2 transcripts between 30 breast cancer tissues and matched adjacent non-cancerous tissues (ANCTs) using real time qPCR technique. There was no significant difference in expression of CD61 or ABCG2 between tumoral tissues and ANCTs (Expression ratios = 1.21 and 0.98, P values = 0.55 and 0.96, respectively). There was a trend toward association between relative expression of CD61 (tumoral tissues versus ANCTs) and patients’ age (P = 0.05) in a way that older patients tended to over-express this marker in their tumoral tissues compared with the matched ANCTs. Moreover, there was a significant association between expression of this gene and tumor size (P = 0.04) in a way that all tumors with sizes less than 2 cm showed down-regulation of CD61 (as compared with the matched ANCTs). Expression of CD61 was significantly higher in tumor tissues with extracapsular nodal extension compared with confined lesions (P = 0.007). Moreover, expression of ABCG2 was significantly higher in tumor tissues of patients aged less than 55 years compared with older patients (P = 0.04). There was no significant correlation between expression of CD61 and ABCG2 either in tumoral tissues or in ANCTs. The current investigation shows association or trends toward association between expression of two cancer stem cell markers and some clinical data of breast cancer patients such as extracapsular nodal extension, age and tumor size which might imply their importance in the pathogenesis of breast cancer.