bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rutile RuxTi1-xO2 nanobelts to enhance visible light photocatalytic activity
Authors: Mihai S. , Cursaru D. L. , Matei D. , Manta A. M. , Somoghi R. , Branoiu G. 
Published: December 2019

AbstractWe herein report on the synthesis by a facile sol-gel method without templates for preparing rutile RuxTi1-xO2 (x = 0.16; 0.07; 0.01) nanobelts with exposed (001) facets. The rutile nanobelts with exposure (001) facets, favor the separation photogenerated electron-hole pairs and inhibit the recombination of the electron-hole pairs resulting in the increase of the number of main superoxide and hydroxyl radicals. The photocatalytic properties of the rutile RuxTi1-xO2 nanobelts were evaluated by discoloring of MB (methylene blue) dye under sunlight irradiation at an intensity of 40000 lx. It was also done a thorough interface analysis to determine the band energy.
Decoding speech from spike-based neural population recordings in secondary auditory cortex of non-human primates
Authors: Heelan Christopher , Lee Jihun , O’Shea Ronan , Lynch Laurie , Brandman David M. , Truccolo Wilson , Nurmikko Arto V. 
Published: December 2019

AbstractDirect electronic communication with sensory areas of the neocortex is a challenging ambition for brain-computer interfaces. Here, we report the first successful neural decoding of English words with high intelligibility from intracortical spike-based neural population activity recorded from the secondary auditory cortex of macaques. We acquired 96-channel full-broadband population recordings using intracortical microelectrode arrays in the rostral and caudal parabelt regions of the superior temporal gyrus (STG). We leveraged a new neural processing toolkit to investigate the choice of decoding algorithm, neural preprocessing, audio representation, channel count, and array location on neural decoding performance. The presented spike-based machine learning neural decoding approach may further be useful in informing future encoding strategies to deliver direct auditory percepts to the brain as specific patterns of microstimulation.
Role of CyPA in cardiac hypertrophy and remodeling
Authors: Cao Mengfei , Yuan Wei , Peng Meiling , Mao Ziqi , Zhao Qianru , Sun Xia , Yan Jinchuan 
Published: December 2019

Abstract
Pathological cardiac hypertrophy is a complex process and eventually develops into heart failure, in which the heart responds to various intrinsic or external stress, involving increased interstitial fibrosis, cell death and cardiac dysfunction. Studies have shown that oxidative stress is an important mechanism for this maladaptation. Cyclophilin A (CyPA) is a member of the cyclophilin (CyPs) family. Many cells secrete CyPA to the outside of the cells in response to oxidative stress. CyPA from blood vessels and the heart itself participate in a variety of signaling pathways to regulate the production of reactive oxygen species (ROS) and mediate inflammation, promote cardiomyocyte hypertrophy and proliferation of cardiac fibroblasts, stimulate endothelial injury and vascular smooth muscle hyperplasia, and promote the dissolution of extracellular matrix (ECM) by activating matrix metalloproteinases (MMPs). The events triggered by CyPA cause a decline of diastolic and systolic function and finally lead to the occurrence of heart failure. This article aims to introduce the role and mechanism of CyPA in cardiac hypertrophy and remodeling, and highlights its potential role as a disease biomarker and therapeutic target.
Characteristic analysis of double excitation sensor based on F‐30 multi‐dimensional digital magnetic measurement system
Authors: Zhang Yanhai , Xu Xiaoli , Zuo Yunbo , Zhang Xiangqi 
Published: December 2019

According to the analysis characteristic of the on‐line sensor of the mechanical device, the on‐line magnetic field of the double excitation sensor is analysed by using the most advanced F‐30 multi‐dimensional digital magnetic measurement system. Using F‐30 mode scanning analysis of the dual incentive sensor of two‐dimensional (2D) and 3D characteristics, a system of a 3D mesh of the sensor is obtained, the 3D graph, the 3D graphic model, at last, through export data for magnetic field distribution of more detailed information. The accuracy of the F‐30 magnetic field analysis system is very high, and the field distribution information of the sensor is more practical. This analysis is of a great reference value for the experimental analysis of the sensor.
Molecular dynamics simulation of fabrication of Ni‐graphene composite: temperature effect
Authors: Safina Liliya L. , Baimova Julia A. 
Published: December 2019

Fabrication of Ni‐graphene composite by hydrostatic pressure at finite temperatures or by the subsequent annealing is studied by molecular dynamics simulation. Crumpled graphene – the network of folded and crumpled graphene flakes connected by van‐der‐Waals bonds – is chosen as the matrix for Ni nanoclusters. It is found that hydrostatic compression at zero or room temperature cannot lead to the formation of the composite structure. Even strongly compressed crumpled graphene after unloading returned to the initial state of separated graphene flakes. However, annealing of the compressed structure at high temperature leads to the appearance of the valent bonds between neighbouring flakes. Simultaneously, hydrostatic compression at high temperature between 1000 and 2000 K leads to the better mixing of Ni atoms inside the structure and to the formation of strong covalent bonds between neighbouring flakes.
A study on the correlation of gastrointestinal bleeding and meteorological factors – is there a weather condition for GI bleeding?
Authors: Prechter Florian , Bürger Martin , Lehmann Thomas , Stallmach Andreas , Schmidt Carsten 
Published: December 2019

Abstract
Aim We tried to identify a possible correlation between meteorological factors and the frequency of gastrointestinal bleeding (GIB).
Methods We analyzed all endoscopic examinations performed because of suspected GIB from 2013 to 2016 at Jena University Hospital, Germany. Confirmed bleeding events were correlated with local meteorological data and meteorological season using multivariate analysis.
Results Among a total of 35 522 examinations, we identified 5310 endoscopies performed for suspected GIB (61.5 % upper, 38.5 % lower endoscopies). In 35.5 %, GIB could be ascertained, gastroduodenal ulcers being the most frequent bleeding source. Of bleedings, 46.7 % merited an endoscopic intervention. Multivariate analysis did not show a correlation between meteorological factors and the total number of bleeding events. In subgroup analysis, lower ambient temperatures as well as pronounced changes in daily temperature were significantly associated with a higher rate of variceal hemorrhage (incidence rate ratio [IRR]: 0.961 for higher minimum temperature, p = 0.019; IRR: 1.119 per degree temperature change, p = 0.021), whereas ulcerative bleeding was associated with changes in air pressure (IRR: 1.031 per hPa, p = 0.010).
Conclusions Our study does not support the correlation of meteorological conditions with the frequency of GIB per se. However, we found a statistically significant increase of variceal bleeding episodes along with lower ambient temperatures and pronounced changes in daily temperature. Patients at risk for variceal hemorrhage should be advised to avoid exposure to low temperatures, whenever possible. Ulcerative bleeding was significantly associated with changes in air pressure.
Neuroendokrine Tumoren in der täglichen gastroenterologischen und endoskopischen Praxis – ein klinisch orientierter Leitfaden
Authors: Spindelböck Walter , Kump Patrizia Katharina , Püspök Andreas , Koch Robert , Mayerhöfer Marius , Haug Alexander , Fritz Eva , Obermayer-Pietsch Barbara , Raderer Markus , Tribl Barbara 
Published: December 2019

ZusammenfassungNeuroendokrine Tumoren des Gastrointestinaltrakts (GI-NET) sind selten. Die im Vergleich zu den mit hormonellen Syndromen assoziierten funktionellen Tumoren (Insulinom, Gastrinom) häufigeren nichtfunktionellen Tumoren verlaufen klinisch in der Regel bis in späte Stadien indolent. Die Therapie der GI-NET ist multimodal, wobei kurative Therapieansätze aus der vollständigen Entfernung des Tumorgewebes auf endoskopischem respektive chirurgischem Weg bestehen. Patienten in späten Tumorstadien profitieren von interventionell-radiologischen oder medikamentösen Therapieverfahren. Der vorliegende Artikel gibt einen praxisnahen Überblick über die Schlüsselaspekte der Therapie von gastrointestinalen NET in der täglichen gastroenterologischen Praxis mit Schwerpunkt auf endoskopischen Diagnose- und Therapieverfahren.
Metabolic and Non-Metabolic Peripheral Neuropathy: Is there a Place for Therapeutic Apheresis?
Authors: Straube Richard , Müller Gregor , Voit-Bak Karin , Tselmin Sergey , Julius Ulrich , Schatz Ulrike , Rietzsch Hannes , Reichmann Heinz , Chrousos George P. , Schürmann Annette , Jarc Luka , Ziemssen Tjalf , Siepmann Timo , Bornstein Stefan R. 
Published: December 2019

AbstractAs the rate of obesity and the incidence of diabetes mellitus have been increasing, diabetic neuropathy has become the most common cause of peripheral neuropathy in developed countries. In addition, a variety of pathogenetically heterogeneous disorders can lead to impairment of the peripheral nervous system including amyloidosis, vitamin deficiencies, uremia and lipid disorders, alcohol abuse, autoimmune and infectious diseases as well as exposure to environmental toxins. We have noted that a combination of these disorders may aggravate the manifestations of peripheral diabetic neuropathy, an effect, which is most pronounced when metabolic and non-metabolic pathologies lead to cumulative damage. Current treatment options are limited and generally have unsatisfactory results in most patients. Therapeutic apheresis (INUSpherese®) allows the removal of metabolic, inflammatory, immunologic and environmental contributors to the disease process and may be an effective treatment option. We reviewed the developments in therapeutic apheresis for metabolic and non-metabolic peripheral neuropathy, including the current literature as well as data from our university diabetes center.
Current Controversies in Sepsis Management
Authors: Moss Stephanie R. , Prescott Hallie C. 
Published: December 2019

AbstractThe overarching goals of early sepsis management include early recognition, appropriate antibiotic therapy and source control, maintenance of hemodynamic stability, and supportive care of organ dysfunction. Despite increasing awareness of the global burden of sepsis, and general agreement on the goals of management, there is ongoing controversy regarding the implementation of specific treatment strategies to optimize patient outcomes. This article will address five current points of controversy in the management of sepsis and septic shock. These include optimal timing of antibiotics in patients with potential sepsis, the role of glucocorticoids in septic shock, vitamin C as a novel therapy for sepsis, the ideal intravenous fluid for resuscitation, and the optimal balance of fluid resuscitation and vasopressor administration in septic shock. For each of these topics, we review relevant literature, discuss areas of controversy, and present our current approach to management.
Controversies Surrounding Renal Replacement Therapy in the Critically Ill Patient
Authors: Iacovella Gina M. , Kumar Neelja 
Published: December 2019

AbstractAcute kidney injury (AKI) commonly occurs in the intensive care unit and is associated with significant morbidity and mortality. Patients with AKI often require initiation of dialysis to control electrolytes, metabolic abnormalities, and volume status. This review will discuss controversies in renal replacement therapy (RRT), including timing of dialysis initiation, dialysis modality and dose, nonrenal indications for dialysis, and the patient population best suited for RRT therapy.
Pain and Delirium in Critical Illness: An Exploration of Key 2018 SCCM PADIS Guideline Evidence Gaps
Authors: Pisani Margaret A. , Devlin John W. , Skrobik Yoanna 
Published: December 2019

AbstractManaging pain and delirium are crucial to patients, families, and caregivers in intensive care units. The Society of Critical Care Medicine 2018 Pain, Agitation/Sedation, Delirium, Immobility, and Sleep disruption (PADIS) guidelines reviewed literature until October 2015 and made its recommendations for critically-ill adults. This chapter addresses evidence gaps, identified during the guideline process, most relevant to clinicians, adds newer evidence published after the PADIS 2018 guidelines were produced, describes hindsight-driven PADIS process or content-related gaps, and reflects on how these considerations may help inform future research investigations and new guideline efforts.
Impact of Travel Distance on Radiation Treatment Modality for Central Nervous System Disease
Authors: McClelland Shearwood , Mitin Timur , Jaboin Jerry J. , Ciporen Jeremy N. 
Published: December 2019

Abstract

Background Stereotactic body radiation therapy (SBRT) has emerged as a popular alternative to conventional radiation therapy (RT) over the past 15 years. Unfortunately, the impact of patient distance from radiation treatment centers and utilization of SBRT versus conventional RT has been sparsely investigated. This report represents the first analysis of the impact of patient distance on radiation treatment modality for central nervous system (CNS) disease.

Materials and Methods Since the inception of our RADIation oncology And Neuro-Surgery (RADIANS) multidisciplinary clinic at a community hospital in 2016, 27 patients have received either SBRT or conventional RT as their sole radiation treatment modality for CNS disease. Twenty-four (88.9%) presented with metastatic disease. Fisher’s exact test evaluated the relationship between patient residence from treatment (in miles) and radiation treatment modality received.

Results Mean patient distance from our RADIANS clinic was 50.6 miles (median = 15.3). Twenty-one patients (77.8%) received SBRT; the remaining six received conventional RT. Mean patient distance from SBRT was 63.6 miles, and mean patient distance for conventional RT was 5.1 miles; this finding was statistically significant (p = 0.0433; 95% confidence interval = 1.9–115.1).

Conclusion Our findings indicate that patients with CNS disease who receive SBRT over conventional RT are statistically more likely to reside further from treatment centers. This is similar to findings of national studies comparing proton versus photon treatment for pediatric solid malignancies. The results from our work have implications for neuro-oncology treatment and the development of community hospital-based clinic models similar to RADIANS in the future.
Influence of the grip width on the reliability and magnitude of different velocity variables during the bench press exercise
Authors: Pérez‐Castilla Alejandro , Martínez‐García Dario , Jerez‐Mayorga Daniel , Rodríguez‐Perea Ángela , Chirosa‐Ríos Luis Javier , García‐Ramos Amador 
Published: December 2019

AbstractThis study aimed to compare the within‐session reliability and magnitude of velocity variables recorded against a range of submaximal loads during the bench press (BP) exercise performed in a Smith machine using different grip widths. Sixteen physically active men (BP one‐repetition maximum [1RM] relative to body mass = 1.01 ± 0.19 kg·kg−1) were randomly tested on 4 sessions using a close grip width (100% of biacromial width), medium grip width (150% of biacromial width), wide grip width (200% of biacromial width), and self‐selected grip width (176 ± 17% of biacromial width). Mean velocity (MV), maximum velocity (Vmax), and vertical displacement were recorded with a linear velocity transducer against the 35%1RM, 55%1RM, and 75%1RM. The main findings revealed that (I) the self‐selected was the only grip width with an acceptable reliability for all loads and velocity variables (CV ≤ 7.56%; ICC ≥ 0.82), (II) the medium grip width provided the highest reliability for MV (CV ratio ≥ 1.20), while a comparable reliability was observed for Vmax using the close, medium and self‐selected grip widths (CV ratio ≤ 1.08), (III) the Vmax showed the highest reliability for all grip widths (CV ratio = 1.68), and (IV) the MV and vertical displacement of the barbell were generally higher for narrow grip widths (close and medium) compared to the wide and self‐selected grip widths, while no significant differences between the grip widths were observed for Vmax (p > .05). Taken together, we recommend the assessment of Vmax using a self‐selected grip width during the routine testing of BP performance against submaximal loads.
Physics beyond colliders at CERN: beyond the Standard Model working group report
Authors: Beacham J , Burrage C , Curtin D , De Roeck A , Evans J , Feng J L , Gatto C , Gninenko S , Hartin A , Irastorza I , Jaeckel J , Jungmann K , Kirch K , Kling F , Knapen S , Lamont M , Lanfranchi G , Lazzeroni C , Lindner A , Martinez-Vidal F , Moulson M , Neri N , Papucci M , Pedraza I , Petridis K , Pospelov M , Rozanov A , Ruoso G , Schuster P , Semertzidis Y , Spadaro T , Vallée C , Wilkinson G 
Published: December 2019

Abstract
The Physics Beyond Colliders initiative is an exploratory study aimed at exploiting the full scientific potential of the CERN’s accelerator complex and scientific infrastructures through projects complementary to the LHC and other possible future colliders. These projects will target fundamental physics questions in modern particle physics. This document presents the status of the proposals presented in the framework of the Beyond Standard Model physics working group, and explore their physics reach and the impact that CERN could have in the next 10–20 years on the international landscape.
Photoluminescence of ZnO/ZnMgO heterostructure nanobelts grown by MBE
Authors: Kennedy Oscar W , Zapf Maximilian , Audinot Jean-Nicolas , Pal Soupitak , Eswara Santhana , Wirtz Tom , Ronning Carsten , Warburton Paul A 
Published: December 2019

Abstract
ZnO nanobelts may grow with their polar axis perpendicular to growth direction. Heterostructured nanobelts therefore contain hetero-interfaces along the polar axis of ZnO where polarisation mismatch may induce electron confinement. These interfaces run along the length of the nanobelts. Such heterostructure nanobelts are grown by molecular beam epitaxy and TEM images confirm the core–shell structure. The effects of shell-growth temperature on nano-heterostructures is investigated using photoluminescence and secondary ion mass spectrometry in a focussed ion-beam microscope with Ne+ as the primary ion beam. We perform low temperature photoluminescence on ensembles of such heterostructures and single nanostructures. We show how single nanobelts have photoluminescence spectra rich in features and attribute these to band misalignment at ZnO/ZnMgO interfaces embedded within nano-heterostructures.
Graded elastic metasurface for enhanced energy harvesting
Authors: De Ponti Jacopo M , Colombi Andrea , Ardito Raffaele , Braghin Francesco , Corigliano Alberto , Craster Richard V 
Published: December 2019

Abstract
In elastic wave systems, combining the powerful concepts of resonance and spatial grading within structured surface arrays enable resonant metasurfaces to exhibit broadband wave trapping, mode conversion from surface (Rayleigh) waves to bulk (shear) waves, and spatial frequency selection. Devices built around these concepts allow for precise control of surface waves, often with structures that are subwavelength, and utilise Rainbow trapping that separates the signal spatially by frequency. Rainbow trapping yields large amplifications of displacement at the resonator positions where each frequency component accumulates. We investigate whether this amplification, and the associated control, can be used to create energy harvesting devices; the potential advantages and disadvantages of using graded resonant devices as energy harvesters is considered. We concentrate upon elastic plate models for which the A
0 mode dominates, and take advantage of the large displacement amplitudes in graded resonant arrays of rods, to design innovative metasurfaces that trap waves for enhanced piezoelectric energy harvesting. Numerical simulation allows us to identify the advantages of such graded metasurface devices and quantify its efficiency, we also develop accurate models of the phenomena and extend our analysis to that of an elastic half-space and Rayleigh surface waves.
Utilizing Sabang sea urchin shell as an inexpensive and alternative heterogeneous catalyst for biodiesel synthesis
Authors: Hayati Z , Ramli M , Mitaphonna R , Nadia Y , Lubis S , Amraini  
Published: December 2019

Abstract
This research is focused on the utilization of sea urchin shells collected from Sabang island, Aceh, Indonesia as raw material for heterogeneous catalyst preparation and Its catalytic study on transesterification reaction of palm oil and methanol to produce fatty acid methyl esters which referred as biodiesel compound. The catalyst was prepared through thermal decomposition method, namely, it was calcined at 900°C in air atmosphere for 4 h and modified with various concentration of potassium element (5, 10, and 20wt.%) as dopant substance using impregnation process. The characterization results using X-Ray Diffraction (XRD) proved that the produced catalyst was dominated by CaO crystals, in which MgO was detected as a minor compound. Another characterization using Scanning Electron Microscope-Energy Dispersive Spectroscopy (SEM-EDS) showed that the produced catalyst has been homogeneous formation on their morphology. Finally, in order to have scientific information regarding its catalytic activity, the prepared catalyst was successfully applied to the transesterification reaction of palm oil and methanol resulting in ricinoleic methyl esters as the main biodiesel product.
Effect of heating using autoclave and microwave on the quality of rice bran as food material
Authors: Panjaitan R F , Febriani  , Helwati H 
Published: December 2019

Abstract
Rice bran is an epidermis of rice produced from 10 - 12% of the rice milling process. Rice bran is susceptible to fat damage due to enzymatic and oxidative processes that cause rancidity, therefore a further process such as heating is needed for stabilization. This study is using the factorial Randomized Block Design (RBD) method, the variables are the type of heating method (autoclave and microwave) and heating duration. Autoclaving (30 min at 75°C) yielded best content value. The heated rice bran has 2.89% water content, 5.79% ash content, 13.87% protein, 7.24% crude fat, 2.68% dietary fibre, 2.04% free fatty acids, and 0.85% peroxides. The contents of free fatty acids, peroxide value, and proximate value from heated rice bran are better than untreated rice bran (control).