bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compatibility of Bifenazate andPhytoseiulus persimilisfor Management of Twospotted Spider Mites in North Carolina Staked Tomatoes
Authors: Bilbo Tom R , Walgenbach James F 
Published: July 2020

AbstractThe twospotted spider mite (TSSM, Tetranychus urticae Koch) is a key pest of tomatoes (Solanum lycopersicon L. [Solanales: Solanaceae]) in North Carolina, and its management has relied principally on synthetic acaricides. Augmentative biological control of TSSM is a commonplace and effective management strategy in greenhouses worldwide, but in field-grown vegetable crops biocontrol of TSSM is poorly developed. We conducted small-plot field experiments in 2016 and 2019 to test the ability of the predatory mite, Phytoseiulus persimilis Athias-Henriot, to establish, disperse, and reduce TSSM in staked tomatoes, as well as test their compatibility with a commonly used reduced-risk acaricide, bifenazate (Acramite). Across both years, the most effective treatment for reducing TSSM was the combination of P. persimilis + Acramite. Phytoseiulus persimilis successfully established both years, but its population growth and dispersal were greater in 2016 than 2019. Acramite alone significantly reduced TSSM pressure in 2019 and P. persimilis alone did not reduce TSSM pressure below the control in either year. However, results in 2016 were influenced by the eventual dispersal of P. persimilis into all experimental plots, despite efforts to hinder their movement with corn barriers. Results in 2019 were influenced by the late-season invasion of TSSM into the trial, which delayed P. persimilis releases and influenced their establishment and growth. This study is the first to demonstrate the utility and limitations of P. persimilis in staked field tomatoes, which is a promising option for growers to manage TSSM in tomatoes in the southeast United States.
Necrotizing fasciitis from perforated sigmoid diverticulitis with subsequent pyoderma gangrenosum: a case report
Authors: Benesch Matthew G K , Bussey Angela S D 
Published: July 2020

Abstract
Postsurgical pyoderma gangrenosum is a very rare form of cutaneous ulceration that is poorly recognized outside of dermatology and in some circumstances has been mistaken for necrotizing fasciitis. Here, we present a rare case of sigmoid diverticulitis with left ureter obstruction that perforated and quickly progressed into necrotizing fasciitis of the left buttock and leg via retroperitoneal spread in an immunocompetent patient. Nearly a year after intense surgical therapy, the patient rapidly developed ulcerating lesions over the left hip which presented a diagnostic dilemma. These were initially thought to represent Marjolin’s ulcers, which would require aggressive local excision. Multiple diagnostic imaging tests and biopsies eventually confirmed pyoderma gangrenosum, which was successfully treated with immunosuppressive therapy. This case highlights the need for a very broad differential diagnosis and wide expertise consultation when managing unusual postsurgical complications, especially when treatment modality critically depends on the correct diagnosis.
Transverse colon volvulus in a patient with autism
Authors: Shah Rony , Klumpp Linda , Negron-Diaz Juan , Carmain Torr , Jordan Jeffrey ,   HCA Healthcare/USF Morsani College of Medicine GME Programs at Citrus Memorial Hospital, Inverness, Florida
Published: July 2020

Abstract
Transverse colon volvulus is an extremely rare cause of bowel obstruction with approximately 100 cases reported in literature. Transverse colon volvulus presents with signs and symptoms of large bowel obstruction, but it can become a surgical emergency due to bowel infarction or peritonitis. We present a rare case of transverse colon volvulus in a 36-year-old male patient with severe autism. We hope this case report will raise awareness of this disease.
中国成人谷类和膳食纤维摄入现状与趋势(1982–2015)
Authors: Dongmei Yu , Liyun Zhao , Wenhua Zhao 
Published: July 2020

Abstract
本研究的目的是分析1982-2015 年中国20 岁及以上成人的谷类
和膳食纤维摄入状况、特点及消费趋势。数据来自五轮中国居民营养
与健康调查的膳食数据，膳食数据的收集均采用连续3 天家庭食物称
重法和24 小时膳食回顾法。结果表明，2015 年中国20 岁及以上成人
人均谷类食物摄入量为281.1 克/日(大米145.6 克/日、小麦粉120.7
克/日、其他谷类14.8 克/日)；膳食纤维摄入量为9.7 克/日，其中3.8 克
来自谷类食物，约占成人膳食纤维总摄入量的40%；我国成人膳食纤
维的另一个主要来源是蔬菜和水果。自1982 年以来，中国居民的谷类
和膳食纤维摄入量呈下降趋势，而精制谷物的消费比例增加。为了促
进中国居民达到全谷物和膳食纤维的推荐摄入量，建议增加全谷物产
品的供应以及公众宣传教育。
1-6OBSTRUCTIVE SLEEP APNEA IN RESISTANT HYPERTENSION
Authors: Pinzon Rizaldy 
Published: July 2020

Background:
HTN is considered resistant when the blood pressure (BP) remains above goal (≥140/90 mmHg) despite lifestyle modification and administration of three antihypertensive agents of different classes, including a diuretic. Obstructive sleep apnea (OSA) is associated with hypoxia, hypercapnia, arousal, and fluctuations of intrathoracic pressure which all contribute to the sympathetic overdrive. The association of resistant hypertension and obstructive sleep apnea are documented in several previous studies. The data from Indonesia are very limited.

Aim:
Measure the association between obstructive sleep apnea and resistant hypertension.

Method:
This is a cross-sectional study. The presence of sleep apnea is measured with complete polysomnography (PSG). Resistant hypertension is generally defined as uncontrolled clinic blood pressure (>140/90 mm Hg) after treatment with three or more antihypertensives. The data about medication were obtained from computerized electronic prescription. The data of adherence are measured with the Morisky Adherence scale. We measure the apnea and hypopnea events per hour, which is called the apnea-hypopnea index (AHI), is used to grade OSA. The data presented in a systematic table.

Result:
The data were obtained from 12 patients with resistant hypertension. The data consist of 8 male and four female. Complete PSG was recorded in all subjects. The result showed that ten patients have obstructive sleep apnea. Severe obstructive sleep apnea (AHI> 30) presence in 7 patients. The data of CPAP/ APAP usage are obtained from 4 subjects. The result showed that blood pressure control is much better after the use of CPAP/ APAP.

Conclusion:
OSA is very prevalent in resistant hypertension. OSA should be evaluated in patients with resistant hypertension.
1-9HYPERTENSION AND ATRIAL VOLTAGES AT ATRIAL APPENDAGES
Authors: Iswandi Cindya Perthy , Starreveld Eliene , Groot Natasja MS de 
Published: July 2020

Background:
Hypertension has been linked with alterations of atrial electrophysiology, which related to the substrate of atrial fibrillation. However, atrial voltages at atrial appendages and their relationship with hypertension remain undiscovered. The study aimed to investigate atrial voltages at both right and left atrial appendages (RAA and LAA) and their correlations with hypertension in patients with underlying heart disease.

Materials & Methods:
Subjects with ischemic and/or valvular heart disease undergoing cardiac surgery at Erasmus Medical Center Rotterdam were included. After the heart was exposed during open chest surgery, high-resolution epicardial mapping of the LAA and the RAA during sinus rhythm was performed before starting cardiopulmonary bypass. Custom-made software was used to measure atrial voltages. A history of hypertension was obtained from the electronic medical record before undergoing surgery.

Results:
Among 133 patients undergoing cardiac surgery, 88 patients (66%) had hypertension. Atrial voltages at the LAA were higher in hypertensive patients compared to non-hypertensive patients (median = 5.36 vs 3.59 p < 0.05), also a correlation between hypertension and atrial voltages at the LAA was identified (r = 0.247, p < 0.05). On the other hand, atrial voltages at the RAA were comparable between hypertensive and non-hypertensive patients (median = 4.30 vs 3.96, p > 0.05), without any correlation was found between hypertension and atrial voltages at the RAA.

Conclusions:
Atrial voltages at the LAA are higher compared to the RAA within hypertensive patients. Hypertension is also correlated with higher atrial voltages at the LAA. High atrial voltages at the LAA might be associated with structural changes of the LAA impacted by systemic hypertension.
2-3THE EFFECT OF IBUPROFEN VS ACETAMINOPHEN ON POSTPARTUM BLOOD PRESSURE IN WOMAN WITH HYPERTENSIVE DISORDER OF PREGNANCY: A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIAL
Authors: Leonardo  , Iskandar Archie F. , Ivan Ignatius , Budiman Fanny , Ruby Rivaldi , Ampri Irfan A. H. 
Published: July 2020

Introduction:
The American College of Obstetricians and Gynecologists (ACOG) suggested replacing NSAIDs with other analgesics for pain relief management of hypertension in pregnancy because of the risk of elevating blood pressure. However, the evidence to support this issue remains unclear. This systematic review aims to investigate the risk of elevated postpartum blood pressure for the woman with hypertensive disorders of pregnancy treated with ibuprofen compared to acetaminophen.

Methods:
We used Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines during our literature search. Pubmed, EBSCOhost, and Proquest were used for database searching up to December 2019. We included studies with the following criteria: English article, human study; randomized controlled trial; relevant patient characteristics; and outcome assessment. Two authors independently assessed the quality of the included study using Cochrane Risk of Bias Tool 2.0 covering six domains with scores of “low,” “high,” “unclear.”

Results:
We identified a total of 79 studies from search strategies. We found four studies that have a relevant issue. One study has an unclear risk of selection bias. Another study has a high risk of performance bias. Moreover, all studies suggested having an unclear risk of detection bias. All studies are randomized controlled trials with a total of 345 participants treated with ibuprofen or acetaminophen. Evaluation for a difference of mean arterial pressure after treatment showed insignificant difference between study groups. Other studies reported measurement with a mean maximum of systolic and diastolic blood pressure and also revealed an insignificant difference between group. Only 1 study suggesting the risk of using ibuprofen for elevating blood pressure which resulted from a significant difference between study group comparing number of patients having blood pressure ≥ 150/100 mmHg after treatment.

Conclusion:
Despite limited studies, we concluded that most studies showed insignificant difference between the use of NSAIDs particularly ibuprofen, compared with other analgesic such as acetaminophen for the risk of elevating blood pressure in woman with hypertensive disorder of pregnancy. Further studies with more extensive trials were necessary to elucidate better quality of evidence.
2-8THE EFFECT OF LACTOBACILLUS CONSUMPTION ON SYSTOLIC AND DIASTOLIC BLOOD PRESSURE: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
Authors: Winston Kevin , Dewangga Raditya , Ilhami Lazuardi G 
Published: July 2020

Introduction:
Gut microbiota has been shown to play an increasingly important role in health with recent data suggesting that probiotics exert ACE-inhibitory activity. As a result, several clinical trials were conducted to assess the effect of probiotics, such as lactobacillus on blood pressure. However, many of these trials provided inconclusive results.

Objective:
To conduct meta-analysis of clinical trials that assess the effect of Lactobacillus probiotic supplementation in lowering systolic and diastolic blood pressure.

Methods:
A comprehensive literature search using PubMed, Scopus, Cochrane Library, EBSCOhost, ProQuest, and JSTOR online for randomized controlled studies comparing the effect of Lactobacillus probiotic versus placebo in lowering blood pressure was performed up to December 2019. The measured outcomes were mean changes in systolic and diastolic blood pressure. Meta-statistics were done using the random-effects model.

Result:
Fourteen randomized clinical trials involving a total of 955 patients met the inclusion criteria. Supplementation of Lactobacillus probiotic produced a statistically significant difference in systolic blood pressure by −2.05 mmHg (95% CI −3.48 to −0.63) and diastolic blood pressure by −2.00 mmHg (95% CI −3.36 to −0.64) when compared with the placebo group.

Conclusion:
Supplementation with Lactobacillus probiotics may lower systolic and diastolic blood pressure by a slight degree. More high-quality studies are needed to confirm this finding.
2-9THE USE OF IBUPROFEN AS POSTPARTUM ANALGESIC IN WOMEN WITH HYPERTENSIVE DISORDER OF PREGNANCY: A SYSTEMATIC REVIEW
Authors: Rudiatmoko Diar Riyanti , Amanda Lia 
Published: July 2020

Background:
Postpartum women are commonly prescribed with non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, which is effective for pain management. However, NSAIDs were known to induced hypertension. Thus, the use of NSAIDs in postpartum women with hypertension is still controversial due to a lack of evidence. This study aims to identify the use of ibuprofen as postpartum analgesics in women with hypertensive disorder of pregnancy.

Methods:
A systematic literature search was conducted using specific keywords with medical subheading (MeSH) terms on PubMed, EBSCOhost, Cochrane, and ProQuest for primary studies published from January 2009 – December 2019. Two authors independently screened and assessed the potential studies using inclusion criteria. The quality of the randomized controlled trial studies was assessed with JADAD scale and Newcastle-Ottawa Quality Assessment Scale (NOS) was used to assess the quality of cohort studies.

Result:
After screening the literature, four randomized controlled trials (RCTs) and two retrospective cohort studies were identified, comprising of 895 total patients. All studies except one RCT showed that ibuprofen did not increase postpartum blood pressure in postpartum women with hypertensive disorders of pregnancy compared with women without the exposure of NSAIDs. Those who were receiving ibuprofen showed no difference in postpartum mean arterial pressure (MAP) compared to control. No significant adverse events were also found in postpartum women.

Discussion:
This review demonstrates that the use of ibuprofen may be beneficial and can be used for postpartum women with hypertension. However, further studies with a larger population are still needed to confirm these results.
3-3ELEVATED MEAN PLATELET VOLUME AND RETINAL VEIN OCCLUSION IN HYPERTENSIVE PATIENTS: A META-ANALYSIS
Authors: Shabrina Nadine Nurani , Sawitri Rakhma Dyah , Shabrina Tiffanny Nur , Ningrum Nurul Rahayu 
Published: July 2020

Background:
In comparison to smaller ones, larger platelets indicate altered reactivity and aggregation. Mean platelet volume (MPV), knowingly used to assess the size, is significantly elevated in hypertension. High MPV is equivalent to a high risk of thrombotic events. Retinal vein occlusion (RVO) is one of the most common extracardiac complications of hypertension, which may lead to vision loss. Assessment of MPV may help to determine the development of the disease.

Objective:
We aimed to analyze if elevated MPV was associated with the incident of RVO, particularly in hypertensive patients.

Method:
A literature search was conducted through PubMed, Cochrane, and Science Direct for primary studies. The abstracts and full text were scanned for potentially relevant articles that fulfilled the inclusion criteria. The quality assessment was done using the Newcastle-Ottawa Quality Assessment Scale (NOS) for case-control studies. We analyzed the data using STATA 14.1.

Result:
Four studies (363 RVO patients and 256 controls) were incorporated into this meta-analysis. Due to the high heterogeneity, a random-effects model was used to calculate the pooled SMD and corresponding 95% confidence intervals. Results have indicated significant increase of MPV levels (SMD = 1.008, 95% CI 0.819–1.197, P < 0.001) and insignificant increase of platelet count levels (SMD = 0.149, 95% CI 0.016–0.313, P = 0.076) in hypertensive patients with RVO compared to controls.

Conclusion:
We found that MPV is strongly associated with the presence of RVO in hypertensive patients. Further studies are required to ascertain the potential clinical use of this simple and relatively inexpensive marker in RVO diagnosis.
3-5IMPROVING HYPERTENSION CONTROL THROUGH GUIDELINE-BASED EDUCATIONAL CARD IN EAST BORNEO PRIMARY HEALTH CARE
Authors: Jhundy B.W. , Siahaan W.F. , Dachi Y.O. , Lestari R.H.D. 
Published: July 2020

Background:
Hypertension is a modifiable risk factor of mortality and disabilities around the globe. Its prevalence has been increasing in the last decade without adequate awareness and control in developing countries. Improving hypertension control is an essential strategy to prevent further Hypertension-Mediated Organ Damage.

Objective:
This study aimed to investigate the effectiveness of Guideline-based educational cards in controlling essential hypertension in East Borneo Primary Health Care.

Method:
Patients with essential hypertension enrolled in this study from February to April 2019. Patients were given a card that consists of their targetted blood pressure, blood pressure, and treatment changes during visits, lifestyle modifications, and additional information about blood pressure management. The physician orally informed all of the information in the card during the first visit. The patients were evaluated weekly and followed for total duration of four weeks. Pre versus post systolic and diastolic blood pressure were evaluated.

Result:
In 46 hypertensive patients, the average age was 57 years old, with 72% were females. 54% of patients had a normal Body Mass Index, and 28% were obese. Diabetes Mellitus presented as another comorbidity in 24% of patients, and only 4% of patients were active smokers. Pre-intervention systolic and diastolic blood pressure was 152 ± 12 mmHg and 90 ± 8 mmHg, respectively. Evaluation of post-intervention blood pressure outcomes revealed a significant reduction by 18 mmHg and 9 mmHg in systolic and diastolic blood pressure (p < 0,0001).

Conclusion:
In conclusion, Guideline-based educational card was an effective strategy in improving blood pressure control and may become a viable approach for other Primary Health Care.
3-10ANGIOTENSIN RECEPTOR NEPRILYSIN INHIBITORS (ARNI) POTENTIALS IN PATIENT WITH HEART FAILURE: A SYSTEMATIC REVIEW
Authors: Puratmaja Nalagafiar , Sjarfi Cheras Yezia Kharismia 
Published: July 2020

Background:
Structural and/or functional cardiac abnormalities that lead to elevated intracardiac pressures with/without reduced output known as heart failure. Progressive establishment of the disease grows concomitantly with the number of cases despite the availability of various therapies. The recent standard recommends the substitution of angiotensin-converting-enzyme (ACE) inhibitors or angiotensin-II receptor blockers (ARBs) with angiotensin receptor blocker-neprilysin inhibitors (ARNI) in selected patients. The capacity of ARNI will be analyzed based on the latest clinical trials available.

Objective:
This study focus on revealing the clinical impact and potentials of ARNI in an attempt to counteract the decreasing capacity of the heart.

Method:
Literature finding involves four scientific databases, including PubMed, EbscoHost, ProQuest, and Cochrane. The primary search was concluded using certain Medical Subject Heading (MeSH) terms and filters. Two independent authors further analyzed selected interventional articles related to ARNI and heart failure. Relevance studies were reviewed using the Centre for Evidence-based Medicine (CEBM) critical appraisal tool to turn aside bias.

The result:
Data were collected from patients in three randomized controlled trials within five articles. Four of the reports investigate the use of ARNI compared to enalapril in acute decompensated heart failure (ADHF) and chronic heart failure (CHF). Another study compared ARNI to valsartan only therapy in heart failure patients with reduced ejection fraction (HFrEF). It shows that the use of ARNI contributes to a lower number of hospitalization cases and mortality rates while preventing further progression of heart failure.

Conclusion:
ARNI has adequate potential to prevent the progression of the disease while the encouragement of future investigation is essential.
4-1SEXUAL DYSFUNCTION IN WOMEN WITH HYPERTENSION: A CROSS-SECTIONAL STUDY
Authors: Magfira Nadya , Helda  
Published: July 2020

Introduction:
Sexual dysfunction (SD) has been recently demonstrated as more frequent in women compared to men, and it is well known that hypertension is a significant risk for SD in male patients. However, data regarding SD in hypertensive women are far from conclusive.

Aim:
the study aimed to evaluate the relationship between SD and hypertension (HT) in women.

Methods:
A cross-sectional study was conducted in a private primary healthcare clinic in Serang Banten, Indonesia, from August to September 2019. The study involved all women aged 18 years or older, being married and sexually active in the past four weeks. Exclusion criteria were pregnant, had a history of pelvic surgery other than section Caesarea, and had a history of diabetes. Patient sexual function was assessed by Indonesian validated Female Sexual Function Index (FSFI-I). Patients were classified as SD if the total FSFI-I score was ≤ 26.55. The variables of the study were demographic and hypertension-related characteristics, depression, and obstetric history. One-way ANOVA and Multivariate logistic regression analysis were performed to evaluate the predictors of SD and calculate the Prevalence Odds Risk (POR) for SD in HT women.

Results:
Of a total of 442 women, 132 women had HT (29.86%, 88 treated, and 44 untreated). SD was found in 92% of hypertensive women compared with 73% of normotensive women (POR: 8.6, 95% Confidence Interval: 2.8–26.7). Furthermore, working women, overweight, and depression increased SD frequency. It was also determined that duration of hypertension is associated with declining of sexual function in women (p=0.03).

Conclusion:
This study showed that SD is more prevalent in hypertensive than in normotensive women. Patients and physicians need to deal with SD and should neither ignore nor superficially address this important issue.
4-6THE ASSOCIATION OF DNA METHYLATION OF A-ADDUCIN IN ESSENTIAL HYPERTENSION: A QUALITATIVE SYSTEMATIC REVIEW
Authors: Khairunnisa Hana , Ilman Atika B , Barry Fathul 
Published: July 2020

Introduction:
Essential hypertension (EH) is one of the most common health problems with significant mortality and morbidity in the world. EH is a complex multifactorial disease resulting from both genetic and environmental factors. α-Adducin (ADD1) is one of several genetic markers that have been identified. DNA methylation is defined as the addition of a methyl group to the DNA molecule, which associated with a change in the activity of DNA segment without the affection of its sequence.

Method:
We comprehensively searched case-control studies about essential hypertension and α-adducin in electronic databases including PubMed, EMBASE, and JSTOR.

Results:
Those three studies (a total 1203 cases and 1148 controls) results were relatively similar, the ADD1 CpG2-5 methylation level was significantly associated with EH, lower CpG1 methylation level was associated with increased risk of EH in females while lower CpG2-5 methylation was associated with an increased risk of EH in males significantly.

Discussion:
EH is an age-related chronic condition affecting males more than females. We found that DNA methylation of ADD1 gene was significantly higher in females than in males. Adducin was implicated in the pathogenesis of EH by modulating Na+-K+-ATPase activity. CpG1 methylation can predict EH among females, and CpG2-5 methylation does among males.

Conclusion:
There was an association of DNA methylation of α-Adducin with essential hypertension.