bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interdisziplinär integriert oder dezentral verteilt? Versorgungssettings im Kontext feminisierender Genitaloperationen – Studienprotokoll zur Hamburger TransCare-Studie
Authors: Köhler Andreas , Strauß Bernhard , Briken Peer , Riechardt Silke , Fisch Margit , Nieder Timo O. 
Published: October 2020

Zusammenfassung
Hintergrund Geschlechtsdysphorie (GD, ehemals Transsexualität) bezeichnet einen Leidensdruck, der sich aus der Inkongruenz zwischen den körperlichen Geschlechtsmerkmalen und dem Erleben des eigenen Geschlechts ergeben kann (Geschlechtsinkongruenz: GIK). Die Gesundheitsversorgung von Personen mit GIK/GD bezieht sich v. a. auf geschlechtsangleichende Maßnahmen (z. B. Hormonbehandlung) und Unterstützung bei assoziierten Bedürfnissen (z. B. durch Psychotherapie). Zudem gelten genitalchirurgische Eingriffe als effektive Verfahren zur Reduktion von GIK/GD und zur Verbesserung der psychischen Gesundheit und Lebensqualität. Als evidenzbasiert gilt eine integrative Gesundheitsversorgung, bei der die beteiligten Bereiche interdisziplinär kooperieren.
Ziel der Studie Bei der medizinischen Versorgung von Patient_innen mit GIK/GD lassen sich grundsätzlich zwei Settings unterscheiden: interdisziplinär integriert an einem Standort vs. dezentral verteilt über mehrere Standorte. Die Trans-Gesundheitsversorgung in Deutschland ist bisher weitgehend dezentral organisiert. Wie sich das Versorgungssetting auf die Wirksamkeit und Qualität genitalangleichender Operationen auswirkt, wurde bisher nicht untersucht. Ziel der TransCare-Studie ist es daher, prospektiv katamnestisch das psychosoziale und klinische Outcome von Patient_innen mit GIK/GD zu untersuchen, die eine feminisierende Genitaloperation in Anspruch nehmen, und auf die möglichen Auswirkungen des Versorgungssettings (interdisziplinär integriert vs. dezentral verteilt) hin zu vergleichen.
Methodik Im Zuge eines naturalistischen Längsschnittdesigns soll eine möglichst praxisnahe Stichprobe rekrutiert und die teilnehmenden Patient_innen prospektiv befragt werden.
Ergebnisse Die Studienergebnisse sollen Erkenntnisse über die Rolle des Versorgungssettings im Rahmen der genitalchirurgischen Behandlung von Patient_innen mit GIK/GD hervorbringen.
Schlussfolgerung Auf Basis der TransCare-Studie soll die Versorgungsqualität empirisch fundiert verbessert werden.
Injuries to the Coronoid Process of the Ulna with Involvement of the
Lesser Sigmoid Notch
Authors: Rausch Valentin , Neugebauer Sina , Leschinger Tim , Müller Lars , Wegmann Kilian , Hackl Michael 
Published: October 2020

Abstract
Introduction This study aimed to describe the involvement of the lesser
sigmoid notch in fractures to the coronoid process. We hypothesized that
injuries to the lateral aspect of the coronoid process regularly involve the
annular ligament insertion at the anterior lesser sigmoid notch.
Material and Methods Patients treated for a coronoid process fracture at
our institution between 06/2011 and 07/2018 were included. We excluded patients
< 18 years, patients with arthritic changes or previous operative treatment
to the elbow, and patients with concomitant injuries to the proximal ulna. In
patients with involvement of the lesser sigmoid notch, the coronoid height and
fragment size (anteroposterior, mediolateral, and craniocaudal) were
measured.
Results Seventy-two patients (mean age: 47 years ± 17.6) could be included
in the study. Twenty-one patients (29.2%) had a fracture involving the lateral
sigmoid notch. The mean anteroposterior fragment length was 7 ± 1.6 mm. The
fragment affected a mean of 43 ± 10.8% of the coronoid height. The mean
mediolateral size of the fragment was 10 ± 5.0 mm, and the mean cranio-caudal
size was 7 ± 2.7 mm.
Conclusion Coronoid fractures regularly include the lesser sigmoid notch.
These injuries possibly affect the anterior annular ligament insertion which is
important for the stability of the proximal radioulnar joint and varus stability
of the elbow.
Path Analysis on Determinants of Childhood Obesity and Associated Risk Factors of Cardiovascular, Renal, and Hepatic Diseases: The CASPIAN-V Study
Authors: Mansouri Vahid , Mansourian Marjan , Qorbani Mostafa , Riahi Roya , Karimi Rahele , Motlagh Mohammad Esmaeil , Heshmat Ramin , Kelishadi Roya 
Published: October 2020

AbstractThe interaction between several lifestyle and obesogenic environmental factors is considered as the main underlying factor for the escalating trend of childhood obesity and its adverse consequences. In this study, we assessed the mutual influence of lifestyle habits and body mass index (BMI) as well as risk factors for cardiometabolic, hepatic, and renal disorders to define the causality power of each item. This nationwide cross-sectional study was conducted as the fifth round of a school-based surveillance program. Overall, 14,800 students living in Iran were studied, and blood samples were obtained from 4,200 of them. Demographic factors, anthropometric and biochemical measures were used to define lifestyle-related latent variables as well as cardiac, renal, and hepatic risk indicators. Total, direct, and indirect effects between factors were analyzed using the standardized regression weights for each pathway. Data from 14,274 students (participation rate of 99%) and 3,843 blood samples were included. All of the latent variables had a significant direct effect on BMI, with the most potent effect of unhealthy nutrition (β ≅ 0.63) in boys and girls. BMI has significant direct effects on risk indicators of cardiovascular, renal, and hepatic diseases with the most powerful effect on cardiovascular risk factors (β ≅  − 0.08). The most important predisposing factor for obesity was unhealthy nutrition, whereas increased activity, adequate sleep, and better hygiene had protective roles. BMI shows the strongest association with indicator of cardiovascular diseases. These findings underscore the importance of implementing public health programs for the prevention of chronic noncommunicable diseases.
Pediatric COVID-19 and the Factors That May Mitigate Its Clinical Course
Authors: Abdel-Aziz Mosaad , Abdel-Aziz Nada M. , Abdel-Aziz Dina M. , Azab Noha 
Published: October 2020

AbstractThe clinical manifestations of novel coronavirus disease 2019 (COVID-19) vary from mild flu-like symptoms to severe fatal pneumonia. However, children with COVID-19 may be asymptomatic or may have mild clinical symptoms. The aim of this study was to investigate clinical features of pediatric COVID-19 and to search for the factors that may mitigate the disease course. We reviewed the literature to realize the clinical features, laboratory, and radiographic data that may be diagnostic for COVID-19 among children. Also, we studied the factors that may affect the clinical course of the disease. Fever, dry cough, and fatigue are the main symptoms of pediatric COVID-19, sometimes flu-like symptoms and/or gastrointestinal symptoms may be present. Although some infected children may be asymptomatic, a recent unusual hyperinflammatory reaction with overlapping features of Kawasaki's disease and toxic shock syndrome in pediatric COVID-19 has been occasionally reported. Severe acute respiratory syndrome-coronvirus-2 (SARS-CoV-2) nucleic acid testing is the corner-stone method for the diagnosis of COVID-19. Lymphocyte count and other inflammatory markers are not essentially diagnostic; however, chest computed tomography is highly specific. Factors that may mitigate the severity of pediatric COVID-19 are home confinement with limited children activity, trained immunity caused by compulsory vaccination, the response of the angiotensin-converting enzyme 2 receptors in children is not the same as in adults, and that children are less likely to have comorbidities. As infected children may be asymptomatic or may have only mild respiratory and/or gastrointestinal symptoms that might be missed, all children for families who have a member diagnosed with COVID-19 should be investigated.
An Interesting Case of Bilateral Upper Limb Wasting: Hirayama Disease
Authors: Eugin Priscilla Rubavathy , Chinnusamy Manokaran , Janakiraman Sathiyanarayanan 
Published: October 2020

AbstractHirayama disease is a rare neurologic disease and is characterized by insidious unilateral or bilateral muscular atrophy and weakness of the forearms and hands without sensory or pyramidal signs. Our patient presented with bilateral upper limb wasting, which is a rarer variant of motor neuron disease. The diagnosis of Hirayama disease is based on dynamic magnetic resonance imaging (MRI). This case displays how dynamic cervical spine MRI can pick up dynamic cord compression and contributes to zero in the diagnosis of Hirayama disease.
Biomechanical Comparison of External Fixation and Double Plating for Stabilization of a Canine Cadaveric Supracondylar Humeral Fracture Gap Model
Authors: Castaldo Sarah , Syrcle Jason , Elder Steve , Wills Robert W. 
Published: October 2020

AbstractObjective Successful stabilization of comminuted supracondylar humeral fractures is challenging, and biomechanical studies are scarce. This study compares double-plate (DB-PLATE) and linear external fixator with an intramedullary pin tie-in (ESF-IMP) fixation techniques in a cadaveric gap model. The hypothesis was the DB-PLATE construct would be stiffer, stronger and more resistant to repeated loading than the ESF-IMP construct in both cyclic and load-to-failure axial compression testing.Study Design A 2 cm ostectomy was performed on 10 pairs of canine cadaveric humeri proximal to the supratrochlear foramen. Stabilization was with DB-PLATE (n = 10) or ESF-IMP (n = 10). Cyclic testing was performed by applying a 200 N load at 2 Hz for 63,000 cycles. Axial compressive load to failure testing followed. Data analysed included dynamic stiffness, stiffness and yield load.Results No constructs failed during cyclic testing or lost stiffness over time. Mean dynamic stiffness over the final 100 cycles was greater for DB-PLATE compared with ESF-IMP. Mean stiffness of DB-PLATE in load-to-failure testing was not different than ESF-IMP. Yield load of DB-PLATE was higher than ESF-IMP.Conclusion Both DB-PLATE and ESF-IMP survived cyclic testing with no change in dynamic stiffness. DB-PLATE was stronger than ESF-IMP in load-to-failure testing, which may make this construct preferable when prolonged healing or poor patient compliance is anticipated. Results suggest that either method may be appropriate for fixation of comminuted supracondylar humeral fractures.
Trigeminal Ophthalmic Branch Schwannoma: Case Report and Literature Review
Authors: Köhler Luiza Rech , Mesquita Filho Paulo Moacir , Santos Fabio Pires , Sawasaki Renato , Giacomelli Richard , Cordeiro Rafael , Ruschel Octavio Karam , Schwingel Daniela 
Published: October 2020

AbstractSchwannomas are the fourth most common primary neoplasms affecting the brain and cranial nerves. Central lesions commonly arise from sensory nerve roots, and a common intracranial site is the vestibular branch of the 8th nerve (>85%). We present the case report of a patient who has a schwannoma extending from the pterygopalatine fossa to the orbit, complaining about facial pain in the trajectory of the trigeminal ophthalmic branch. Schwannomas represent 1 to 2% of all neoplasms of the orbit, and trigeminal schwannomas are extremely rare, accounting for less than 0.5% of all intracranial tumors.
A Novel Mutation in NIPBL Gene with the Cornelia de Lange Syndrome and a 10q11.22-q11.23 Microdeletion in the Same Individual
Authors: Bağış Haydar , Öztürk Özden , Bolu Semih , Taşkın Bayram 
Published: October 2020

AbstractThe Cornelia de Lange syndrome (CdLS) is a genetic disorder characterized by multisystemic malformations. CdLS is due to mutations in one of the following genes: NIPBL, SMC1A, SMC3, RAD21, and HDAC8. On the other hand, 10q11.2 deletions cause a wide range of presentations in patients. Approximately 40 cases with variable deletions of 10q11.2 have been reported in literature. Some of the reported cases involve the coexistence of duplication or deletion affecting one copy of the chromosome. However, deletion of chromosome 10q11.22-q11.23 and CdLS syndrome caused by NIPBL gene mutations have not been reported previously. This report, therefore, is the first to report their coexistence together.
Case Series of Three Patients with Rifampicin-Induced Thrombocytopenia
Authors: M.T Chandramouli 
Published: October 2020

AbstractLife-threatening adverse reactions of antitubercular drugs are uncommon; however, thrombocytopenia is one such rare complication encountered with rifampicin, isoniazid, ethambutol, and pyrazinamide. Rifampicin is the most effective drug and its use in the tuberculosis treatment led to the emergence of modern and effective short-course regimens. I am reporting case series of three patients with pulmonary tuberculosis presented with rifampicin-induced thrombocytopenia.
Large Retroperitoneal Leiomyosarcoma
Authors: Saad Melissa Kyriakos , Ghandour Fatme , Abdallah Ali , Ghantous Imad , Raad Roy , Saikaly Elias 
Published: October 2020

AbstractRetroperitoneal sarcomas, such as leiomyosarcoma, often invade or displace vital organs in the abdominal cavity and exhibit an aggressive clinical course. Complete surgical resection of the tumor with en-bloc resection of adjacent adherent organs is the cornerstone in management of retroperitoneal leiomyosarcoma.
Conflict-motivated acts in the open letters of two former Nigerian presidents
Authors: Unuabonah Foluke Olayinka , Boluwaduro Eniola 
Published: October 2020

Abstract
This study investigates conflict-motivated pragmatic acts employed in the open letters exchanged by two former Nigerian
presidents (Olusegun Obasanjo and Goodluck Jonathan). The data are analysed using Mey’s pragmatic act theory. The findings reveal that while
Obasanjo employs pragmatic acts of warning, appealing, and praising in order to counsel Jonathan, Jonathan employs pragmatic acts of
acknowledging, boasting, correcting, and reminding in order to defend himself. However, they both employ the pragmatic acts of insulting, complaining, accusing, and requesting. These acts are influenced by nationalist and anti-ethnic ideologies as well as the context of the
open letters, i.e., conflict among political leaders in Nigeria.
Synthesis and magnetic properties in quaternary Ca1−x
Pr
x
Co2As2 single crystals
Authors: Zhang Wei , Zong Bingbing , Cao Yating , Sun Peng , Zhang Ziyi , Qiu Xianggang , Zhao Run , Liu Huayi , Fu Yueju , Zhang Kai , Li Yubao 
Published: October 2020

Abstract
Series of Ca1−x
Pr
x
Co2As2 (x = 0, 0.10, 0.25, 0.4, 0.6, 0.75, 0.85, 1) single crystals have been synthesized in order to clarify the variation of magnetic order from antiferromagnetic (AFM) in CaCo2As2 to ferromagnetic (FM) in PrCo2As2. It is found that the lattice constant of c-axis are contracted with the introduction of Pr into Ca sites in CaCo2As2. Electronic transport measurements reveal the metallicity in this system. Systematic magnetic measurements and analysis show that substituting only 10% of Pr for Ca changes the magnetic ground state from A-type AFM ordering of Co magnetic moment in CaCo2As2 to FM ordering in Ca1−x
Pr
x
Co2As2 (0.1 ⩽ x ⩽ 1). Most importantly, the abrupt drop of low temperature magnetic susceptibility below T
FiM with x ⩾ 0.25 and the observed magnetic pole reversal with x ⩾ 0.4 suggests an AFM coupling between Co 3d and Pr 4f magnetic sublattice. Finally, a detailed magnetic phase diagram in this system has been obtained.
Solar energy application for LFR unit with trapezoidal cavity receiver considering radiative mode
Authors: Ebrahimpour Z , Sheikholeslami M , Farshad Seyyed Ali , Shafee Ahmad 
Published: October 2020

Abstract
In current article, influence of radiation and convection modes on behavior of air inside an absorber in trapezoidal shape has been investigated. Such cavity is part of Linear Fresnel Reflector (LFR) unit and it is important to analyze such geometry to reach higher performance. Properties of carrier fluid were assumed as function of temperature. To involve radiation effect, discrete ordinates model was implemented. Influences of external convective factor (hext), Angle of adiabatic wall (θ), temperature ratio (Tr) on irreversibility and heat transfer were depicted in outputs. Augment of Tr, θ and hext cause incident radiation to decline about 85.95%, 20.97% and 20.68% with assuming lowest values of other factors. Strength of eddy, temperature difference augments about 180% and 9.77% when θ enhances at Tr = 0.8. With considering highest level of other factors, as values of wind speed and θ intensify, Nu enhances 9.28% and 17.36% while it declines about 52.2% with rise of Tr. Given minimum values of other parameters, irreversibility intensifies about 45.45% and 8.3% with augment of hext and θ but it declines about 84.44% with augment of Tr.
Abnormal stiffness behaviour in artificial cactus-inspired reinforcement materials
Authors: Zampetakis Ioannis , Dobah Yousef , Liu Dong , Woods Ben , Bezazi Abderrezak , Perriman Adam , Scarpa Fabrizio 
Published: October 2020

Abstract
Cactus fibres have previously shown unusual mechanical properties in terms of bending and axial stiffness due to their hierarchical structural morphology. Bioinspiration from those cactus fibres could potentially generate architected materials with exciting properties. To that end we have built bioinspired artificial analogues of cactus fibres to evaluate their mechanical properties. We have generated 3D printed specimens from rendered models of the cactus structure using two different printing techniques to assess the reproducibility of the structural topology. Bioinspired additive manufactured materials with unusual mechanical properties constitute an ever-evolving field for applications ranging from novel wing designs to lightweight plant-inspired analogues. The cactus-inspired 3D printed specimens developed here demonstrate an unusually high bending to axial stiffness ratios regardless of the manufacturing method used. Moreover, when compared to their equivalent beam analogues the cactus specimens demonstrate a significant potential in terms of specific (weight averaged) flexural modulus. Imaging of the artificial cactus reinforcements has enabled the generation of a one-dimensional reduced order finite element model of the cactus structure, with a distribution of cross sections along the length that simulate the inertia and mechanical behaviour of the cactus topology. The novel bioinspired material structure shows an excellent reproducibility across different manufacturing methods and suggest that the tree-like topology of the cactus fibre could be very suited to applications where high bending to axial stiffness ratios are critical.
Influence of the integrity of tendinous membrane and fascicle on biomechanical characteristics of tendon-derived scaffolds
Authors: Cui Jing , Ning Liang-Ju , Yao Xuan , Zhang Yi , Zhang Yan-Jing , He Shu-Kun , Zhang Zhong , Ding Wei , Luo Jing-Cong , Qin Ting-Wu 
Published: October 2020

Abstract
The biomechanical characteristics of tendon grafts is essential for tendon reconstructive surgery due to its great role in providing a good mechanical environment for tendon healing and regeneration. In our previous studies, the decellularized tendon slices (DTSs) and decellularized bovine tendon sheets (DBTSs) scaffolds were successfully developed. However, the influence of the integrity of tendinous membrane (endotenon and epitenon) and fascicle on biomechanical characteristics of these two scaffolds was not investigated. In this study, we assessed the integrity of tendinous membrane and fascicle of the tendon derived scaffolds and its effect on the biomechanical characteristics. The results of histological staining indicated that the DBTSs had complete endotenon and epitenon, while DTSs had no epitenon at all, only part of endotenon was remained. Furthermore, the DBTSs, and DTSs with thickness of 900 μm had complete fascicles, while DTSs with thickness less than 600 μm had almost no complete fascicles. The fibrous configuration of epitenon was well-preserved in the surface of the DBTSs but the surface ultrastructure of the DTSs was aligned collagen fibers based on scanning electron microscopy examination. The results of transmission electron microscopy showed that there was no significant difference between the DBTSs and DTSs. Mechanically, the DBTSs and DTSs with thickness of 900 μm showed similar ultimate tensile strength and stiffness to native tendon segments (NTSs). The strain at break and suture retention strength of the DBTSs showed much higher than that of the DTSs (p < 0.05). Additionally, the DBTSs showed higher ultimate load than the DTSs when these scaffolds were sutured with NTSs (p < 0.05) through the modified Kessler technique based on a uniaxial tensile test. This study demonstrated that DTSs may be used as a patch for reinforcing tendon repair, while DBTSs may be used as a bridge for reconstructing tendon defects.
North American cold events following sudden stratospheric warming in the presence of low Barents-Kara Sea sea ice
Authors: Zhang Pengfei , Wu Yutian , Chen Gang , Yu Yueyue 
Published: October 2020

Abstract
While the relationship between the Arctic sea ice loss and midlatitude winter climate has been well discussed, especially on the seasonal mean scale, it remains unclear whether the Arctic sea ice condition affects the predictability of North American cold weather on the subseasonal time scale. Here we find that, in the presence of low Barents-Kara Sea (BKS) sea ice, sudden stratospheric warmings (SSWs) can favor surface cold spells over North America at the subseasonal timescale based on observations and model experiments. A persistent ridge of wave-2 pattern emerges over the Bering Sea-Gulf of Alaska several weeks after the SSW onset, with a coherent structure from the stratosphere to the surface, which, in turn, is conducive to synoptic cold air outbreaks in Canada and midwestern USA. This highlights a planetary wave pathway relating to BKS sea ice changes, by which the stratospheric polar vortex impacts the regional surface temperature on the subseasonal scale. In contrast, this mechanism does not occur with positive BKS sea ice anomaly. These findings help to improve the subseasonal predictability over North America, especially under the background of rapid change of Arctic sea ice in a warming world.
Direct mineralization of atmospheric CO2using natural rocks in Japan
Authors: Myers Corey , Nakagaki Takao 
Published: October 2020

AbstractGas-solid mineralization of atmospheric CO2using naturally abundant surface rocks under ambient conditions and without thermochemical treatment was analyzed for application in Japan. Based on an empirically-verified theoretical framework, a tiered greenhouse containing finely ground rocks was designed with low-speed induced airflow to realize CO2mineralization reactions over 1 year. Negative CO2emissions were calculated accounting for CO2emissions from energy generation, materials production, and removal of vegetation and soil. Under practicable operating conditions, negative emissions using crystalline surface rocks in Japan can reach ∼7.6 Gt-CO2/y achieved across 726 sites. The average energy requirement was calculated to be 1.5 GJ t−1-CO2with an average land requirement of 1.1 km2per Mt-CO2annual removal capacity. Carbon debt is paid off after 60 d of operation.