bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced Formation Evaluation in the Permian Basin Using a Novel Field-Scale Workflow Including Wells with Missing Data
Authors: Garcia Artur Posenato , Jagadisan Archana , Hernandez Laura M. , Heidari Zoya , Casey Brian , Williams Rick 
Published: May 2020

SummaryReliable formation evaluation in organic-rich mudrocks requires integrated interpretation of well logs and core measurements. More than 80% of the Permian Basin wells have incomplete data sets, lacking photoelectric factor (PEF) or other logs required for reliable formation evaluation in the presence of complex mineralogy. Hence, we develop a novel workflow to reliably estimate rock properties in wells with incomplete data to enhance reservoir characterization and completion decisions. We propose to use integrated rock classification for enhanced physics-based assessment of rock properties in wells with missing data; combine field-scale geostatistical and machine learning methods to reliably reconstruct missing PEF logs with a confidence interval through a rock-type-based approach, which is a unique contribution of this work; and quantify the uncertainty in estimates of petrophysical properties.We performed a preliminary field-scale formation evaluation on wells with triple-combo logs (more than 70 wells). Next, we performed an initial rock typing and reconstructed the missing PEF logs by combining supervised neural networks with geostatistical analysis on a rock-type basis. We then used an unsupervised neural network method to improve the rock classification based on the updated estimates of petrophysical and compositional properties after PEF reconstruction. The combined rock classification and PEF reconstruction was performed iteratively to improve the multimineral analysis results in all wells with missing data. We successfully applied the new workflow to 20 wells in blind tests. The reconstructed well logs agreed with the actual measurements with relative errors of less than 10%.The new workflow extends the boundaries of reliable formation evaluation, enabling accurate reservoir characterization and completion decisions by enhancing evaluation of wells with missing data. The proposed method can also be applied to wells with other types of missing data.
Surrogate-Based Optimization for the Design of Rotary Gas Separator in ESP Systems
Authors: Abbariki Ghasem , Riasi Alireza , Rezghi Ali 
Published: May 2020

Summary
The rotary gas separator (RGS) is used to separate gas from the two-phase flow and reduce input gas into the electrical submersible pumps (ESPs). When the pump handles flow with high gas void fraction (GVF), it causes deterioration of the head and performance of the pump system. Thus, performance prediction of the RGS is very important. In this study, optimization of separator blades in the RGS is carried out using computational fluid dynamics (CFD), and surrogate methods are used to increase gas separation efficiency. Three-dimensional (3D) Navier-Stokes equations are solved by using the Euler-Euler approach for the inhomogeneous two-phase flow (water/air), and modeling interphase forces in ANSYS® CFX 15.0 software (ANSYS, Inc., Canonsburg, Pennsylvania, USA). The kriging (KRG) model is used to approximate the objective function as a function of design variables including the inlet angle, straight blade length, and tip-clearance gap. Sensitivity analysis showed that the tip-clearance gap has more effect on efficiency. The results for optimized values indicated that the separation efficiency increased, and efficiency is progressively transferred from the high-efficiency region to the low-efficiency region.
Titles: Caregiver's perspectives on facilitators and barriers of active participation in cerebral palsy rehabilitation in North West Nigeria: a qualitative study
Authors: Isah Auwal , Abdullahi Auwal 
Published: May 2020

Abstract

Background: Cerebral Palsy (CP) is a group of permanent disorders of movement and posture, attributed to non-progressive disturbance that occurred in the developing fetal or infant brain. The condition results in long-term disability in carrying out activities of daily living (ADL). Thus, active participation of caregivers in the rehabilitation of their children with CP is required.Objective: The aim of this study is to explore the facilitators and barriers of active participation of caregivers in the rehabilitation of children with CP in Kano, Nigeria.Materials and Methods:The study design used was qualitative in-depth interview. The participants consisted of caregivers of children with CP attending Hasiya Bayero Paediatric Specialists Hospital, Kano. The caregivers were sampled and interviewed by one of the researchers until theoretical saturation was attained. Responses of the participants were audio-recorded with a tape recorder, supplemented with note taking. The data generated from the interview was then transcribed, coded and analyzed using matrix analysis, using constant comparative analysis.Results:Forty caregivers with mean age, 27.17±4.46 years participated in the study.The results of the study showed factors that facilitate active participation of caregivers of children with CP in the rehabilitation of their children are improvement in the child’s condition, family support, improvement in the conditions of other children with CP, encouragement from the therapist managing the child, empathy, and cooperation of the child during home programs. The barriers identified are number of children the caregiver has, caregiver’s occupation and financial resources.Conclusion:Therapists need to help reinforce these facilitators, and devise strategies to help caregivers overcome barriers during rehabilitation of children with CP. Economically sustainable and accessible rehabilitation services are needed for all children with CP. Similarly, sharing caregiving rehabilitation tasks amongst family members could facilitate caregiver active participation.
Branches of the brachiocephalic was an independent risk factor for hemorrhagic pulmonary sheath (HPS) patients with acute Stanford A aortic dissection
Authors: Xie Qiuxia , Qin Haoling , Lin Ling , Guan Jian , Zhou Xuhui 
Published: May 2020

Abstract
Background: AAD refers to the blood flow into the middle membrane through the intimal rupture of the aorta. Hemorrhagic pulmonary sheath (HPS) is a common complication of Stanford-A AAD. The risk factors of HPS are remaining unclear Methods: In this study, we have probed the potential risk factors of HPS patients with acute Stanford A aortic dissection. 18 HPS patients with acute Stanford A aortic dissection were selected as the case group. The age difference ± 5 years and the same sex are set as the matching principles. 36 patients with acute Stanford-A type AD who did not detect HPS in the same period were matched according to the ratio of 1:2. Demographic data, treatment methods, AD-related disease history, clinical symptoms and Charlson comorbidity index (CCI) values of each patient were collected. Meanwhile, the values of the maximum diameter of ascending aorta (mm), aortic dissection range, and the main branch of the aorta, pleural effusion/blood, and pericardial effusion/blood were measured by two experienced cardiovascular radiological physicians. Univariate and multivariate conditional logistic regression analysis was used in this study. Results: CCI value and the branches of the brachiocephalic in the case group were significantly higher than those in the control group (p<0.05). Univariate conditional logistic regression analysis showed CCI and branches of the brachiocephalic were associated with HPS. Multivariate conditional logistic regression analysis suggested that branches of the brachiocephalic were an independent risk factor for HPS (OR=7.02, 95%CI=1.28-38.62, p=0.025). Conclusions: Branches of the brachiocephalic were an independent risk factor for HPS.
Dissatisfaction between medical providers and patients in the Republic of Kazakhstan.
Authors: Zhumadilova Anara , Kozhakhmetova Aizhan , Kuanyshbayeva Gaukhar , Kazhen Madina , Akhmadiyeva Amina , Craig Brett J. 
Published: May 2020

Abstract
Background: Dissatisfaction among patients towards health care providers remains a serious concern in the Republic of Kazakhstan that requires further attention(1-3). Patient-centred care, trust between patients and medical providers, the involvement of patients in their own treatment process, and effective communication are major areas in need of strengthening in order to improve outcomes of medical care (4-7). The objective of this study was to broaden the investigation of patient dissatisfaction to various departments from different medical facilities in the city of Nur-Sultan and examine additional factors that may be influencing provider-patient communication and contributing to patient dissatisfaction. Methods: This cross-sectional study of 500 patients (response rate, 85.4%) and 500 health care providers (response rate, 86.4%) from one private and one state hospital and two state policlinics (outpatient departments) in the city of Nur-Sultan, Kazakhstan, used questionnaires containing the Patient-Practitioner Orientation Scale (PPOS) and scales assessing life and job satisfaction, job effort-job reward balance, and patient evaluation of communication. Results: Our study showed that the majority of health care providers and patients were doctor-centred as opposed to patient-centred in their expectations of the doctor visit. The patient-centred orientation of health care providers was negatively correlated with age (P=0.000218) and life satisfaction (P=0.000001). In patients, contrarily, patient-centredness was enhanced by higher life satisfaction (P=0.040), although negatively correlated with age (P=2.659E-21). Conclusions: The results of this study demonstrate that younger health care providers and those with lower life satisfaction expect a more patient-centred approach to the doctor visit. Older respondents and those with higher life satisfaction, in contrast, reported doctor-centred attitudes. The majority of younger patients have a stronger belief in good health associated with patient-centred care whereas the older population preferred a more doctor-centred approach to care. In all patients, the preference for patient-centred care was associated with higher satisfaction in life.
Identification of QTL for resistance to root rot in sweetpotato (Ipomoea batatas (L.) Lam) with SSR linkage maps
Authors: Ma Zhimin , Gao Wenchuan , Liu Lanfu , Liu Minghui , Zhao Ning , Han Meikun , Wang Zhao , Jiao Weijing , Gao Zhiyuan , Hu Yaya , Liu Qingchang 
Published: May 2020

Abstract
Background: Sweetpotato root rot is a devastating disease caused by Fusarium solani that seriously endangers the yield of sweetpotato in China. Although there is currently no effective method to control the disease, breeding of resistant varieties is the most effective and economic option. Moreover, quantitative trait locus (QTL) associated with resistance to root rot have not yet been reported, and the biological mechanisms of resistance remain unclear in sweetpotato. Thus, increasing our knowledge about the mechanism of disease resistance and identifying resistance loci will assist in the development of disease resistance breeding. Results: In this study, we constructed genetic linkage maps of sweetpotato using a mapping population consisting of 300 individuals derived from a cross between Jizishu 1 and Longshu 9 by simple sequence repeat (SSR) markers, and mapped seven QTLs for resistance to root rot. In total, 484 and 573 polymorphic SSR markers were grouped into 90 linkage groups for Jizishu 1 and Longshu 9, respectively. The total map distance for Jizishu 1 was 3,974.24 cM, with an average marker distance of 8.23 cM. The total map distance for Longshu 9 was 5,163.35 cM, with an average marker distance of 9.01 cM. Five QTLs ( qRRM_1 , qRRM_2 , qRRM_3, qRRM_4 , and qRRM_5 ) were located in five linkage groups of Jizishu 1 map explaining 52.6–57.0% of the variation. Two QTLs ( qRRF_1 and qRRF_2 ) were mapped on two linkage groups of Longshu 9 explaining 57.6% and 53.6% of the variation, respectively. Furthermore, 71.4% of the QTLs positively affected the variation. Three of the seven QTLs, qRRM_3 , qRRF_1 , and qRRF_2 , were colocalized with markers IES43-5mt, IES68-6fs**, and IES108-1fs, respectively. Conclusions: To our knowledge, this is the first report on the construction of a genetic linkage map for purple sweetpotato (Jizishu 1) and the identification of QTLs associated with resistance to root rot in sweetpotato using SSR markers. These QTLs will have practical significance for the fine mapping of root rot resistance genes and play an important role in sweetpotato marker-assisted breeding.
Optimizing the Efficiency and Implementation of Cash Transfers to Improve Adherence to Antiretroviral Therapy: Study Protocol for A Cluster Randomized Controlled Trial
Authors: Packel Laura , Njau Prosper , Fahey Carolyn , Ramadhani Angela , Dow William H , Jewell Nicholas P , McCoy Sandra I 
Published: May 2020

Abstract
Background : Antiretroviral therapy (ART) for HIV, taken daily, is an effective strategy to clinically suppress the virus, providing the dual benefit of improved survival and vastly decreasing the risk of transmission. However, this highly effective intervention has not yet reached all who could benefit. Cash transfers are increasingly recognized as an effective strategy to motivate behavior change and improve outcomes along the HIV care continuum, including engagement in HIV care and adherence to ART. Despite a growing evidence base and strong theoretical foundation for the cash transfer approach, key questions remain. Specifically, gaps exist in understanding: 1) whether short-term cash transfers can increase viral suppression in larger, effectiveness studies; and 2) an implementation model or set of best practices that facilitate scale up and enhance sustainability. To address these questions and begin to bridge the “know-do gap” with respect to cash transfers, our team is employing an implementation science approach to iterative development of an incentive-based implementation strategy to promote ART uptake and adherence among people living with HIV (PLHIV) in the Lake Zone Region, Tanzania.Methods: We will conduct a type I hybrid implementation – effectiveness trial to test the effectiveness of a cash transfer intervention on the outcome of HIV viral suppression, and concurrently examine the potential for real-world implementation with an mHealth system through measurement of implementation science constructs. Specifically, our team will expand the intervention to 32 clinics and enroll 1,984 PLHIV to (a) evaluate its effectiveness by conducting a cluster randomized controlled trial with clinics as the unit of randomization and 12-month viral suppression as the primary outcome – a key indicator for monitoring progress towards HIV epidemic control; and (b) evaluate the implementation challenges and successes by measuring implementation outcomes at multiple levels (patient, provider, clinic). Discussion: This trial will provide evidence about not only the real-world effectiveness of cash transfers for retention in HIV care and viral suppression, but also on the implementation challenges and successes that will facilitate or hinder wider scale-up within Tanzania and beyond.
Providing medical care for suspected human trafficking victims: Perceptions among a cohort of health care providers in Myanmar
Authors: Zachariah Sybil , Sharma Ashish , Bills Corey B , Ohn Htoo Ma (Tony) , Walker Rebecca 
Published: May 2020

Abstract
Background: Myanmar is a source country for men, women, and children who are subject to human trafficking and forced labor. Given that human trafficking and forced labor victims frequently experience physical and mental health concerns, healthcare practitioners have a unique opportunity to identify and assist victims. This study aims to understand the attitudes, perspectives, and levels of comfort for healthcare providers in caring for victims of human trafficking. It also seeks to understand the types of additional educational resources that could better equip medical personnel to improve care for survivors of human trafficking.Methods: A 20-question survey collected data anonymously from a convenience sample of healthcare providers that attended a one-day emergency care conference in Yangon, Myanmar.Results: While a significant number (70%) of medical professionals surveyed reported that they feel the problem of abuses for labor or sex in the community was "serious" or "very serious", a majority of them felt neutral or uncomfortable about identifying patients that are currently being abused in some way. Only 2% of respondents felt comfortable identifying victims of abuse. Over half of the healthcare workers surveyed indicated they would be interested in attending conferences, symposia, or lectures specific to human trafficking and receiving training in identifying victims and assisting victims of exploitation.Conclusions: Health care providers in Myanmar consider labor and sex trafficking as a significant problem in their community, but do not feel adequately trained to identify and help victims of exploitation. Given that even brief educational interventions can increase providers knowledge and self-reported recognition of human trafficking victims, there is a window of opportunity in Myanmar to provide training to currently practicing health providers.
Longitudinal prospective evaluation of oral health-related quality of life in young patients undergoing fixed orthodontic appliance treatment as part of a randomised trial
Authors: Elhussein Mustafa , Benson Philip 
Published: May 2020

Abstract
Background

The objectives of this study were to investigate relationships between change in the aesthetic appearance before and after orthodontic treatment and patient-reported change in oral health-related quality of life (OHRQoL), and to assess the responsiveness of two OHRQoL measures to any changes from orthodontic treatment.
Methods

Two hundred and ten participants in a multicentre (two teaching hospitals and four specialist orthodontic practices), single blinded, randomised clinical trial with 2 parallel groups, were administered one of two age-specific questionnaires, either the Child Perceptions Questionnaire (CPQ11-14-ISF-16) or the Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ), before and after orthodontic treatment. Clinical photographs were assessed by two groups of laypeople and orthodontists using the Index of Orthodontic Treatment Need Aesthetic Component (IOTN-AC).
Results

Two hundred and ten participants were randomised, and 197 completed the trial. Before and after OHRQoL data were successfully obtained from 110 participants. There was a mean reduction in the total CPQ11-14-ISF-16 scores of 3.9 (SD = 8.0), and a mean reduction of 34.2 (SD = 18.5) in the total PIDAQ score. CPQ11-14-ISF-16 demonstrated poor longitudinal construct validity (p = 0.155). Correlations between the change in total CPQ11-14-ISF-16 scores and change in IOTN-AC assessments were small for both orthodontists (r=-0.084; p = 0.516) and laypeople (r=-0.140; p = 0.225). There were higher associations between the improvement in the Social well-being (SWB) subdomain and improvement in IOTN-AC. Correlations between the changes in total PIDAQ scores and the IOTN-AC assessments, were higher in comparison to the correlations with CPQ11-14-ISF-16 (orthodontists; r = 0.223, laypeople; r = 0.025). There were no adverse effects.
Conclusion

CPQ11-14-ISF-16 and IOTN-AC measure different attributes. This demonstrated the role of SWB on children OHRQoL. Condition-specific measures (PIDAQ) are more responsive to change in self-reported OHRQoL than generic measures (CPQ11-14-ISF-16) after treatment.
Trial Registration:

The trial was registered at ClinicalTrials.gov NCT01925924.
Comparative In Vitro Quality Evaluation of Different Brands of Ibuprofen Tablets Marketed in Mekelle, Ethiopia
Authors: Welegebrial Brhane Gebrehiwot , Kahsay Getu , Eticha Tadele , Gebretsadik Hailekiros 
Published: May 2020

Abstract
Objective Quality of pharmaceutical products is required to guarantee their safety and efficacy. The aim of this study was to evaluate the physicochemical quality attributes of different brands of ibuprofen tablets marketed in Mekelle, Ethiopia. The methods stated in the British Pharmacopeia were adopted for weight uniformity, hardness, friability, disintegration test and assay of drug content. Dissolution test was also carried out as stated in the United States Pharmacopeia. To compare dissolution profile, statistical analysis of drug release at different time points were employed.Results All the brands were found with acceptable pharmacopeial specifications for weight uniformity, friability, hardness, assay of drug content and dissolution test. Six brands fulfilled the pharmacopeial requirements of disintegration test while one brand failed to disintegrate as per the BP specification. However, there were statistically significant difference in weight, hardness, disintegration, dissolution and amount of drug content among the tested samples. Thus, from this study we can conclude that all the products fulfilled the required quality evaluation parameters as stipulated in pharmacopeias except one brand which failed the disintegration test. However, the in vitro dissolution profile indicated that there may be a potential bio-in equivalence among the pharmaceutical products.
Estimating Sex from second and seventh cervical vertebras in Iranian adult population using Computed Tomography scan images
Authors: Mostafavi Reza Saadat , Memarian Azadeh , Amiri Arezoo , Motamedi Omid 
Published: May 2020

Abstract
Objectives The study aimed to estimating the sex from several metric dimensions of second and seventh cervical vertebras using Computed Tomography (CT) scan images of a series of Iranian adult populations. In this study, sexual dimorphism of 15 indexes of second cervical vertebra and 10 indexes of the seventh cervical vertebra were investigated. Indexes were obtained from CT scan images of 70 patients who underwent CT scan imaging for other indications.Results Among measured dimensions of the second vertebra, 9 were associated with sex. Of these indexes, Maximum width of the superior Facet and Maximum height of axis were independent predictors of sex with correct sex classification of 81.4% when used in combination. Four of 10 seventh vertebra’s indexes were associated with sex: Length of superior facets, Length of the inferior surface of the vertebral body, Width of the inferior surface of the vertebral body, and the Length of spinous process. Length of the inferior surface of the vertebral body and the Length of spinous process were independent sex predictors and together provided sex classification accuracy of 78.6%. We found considerable accuracy in sex classification by using metric dimensions of second and seventh cervical vertebras in the Iranian adult population.