bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic Buffer Analysis Reveals the Simultaneous, Independent Control of ATP and Adenylate Energy Ratios
Authors: Hancock Edward J. , Krycer James , Ang Jordan 
Published: February 2020

AbstractDetermining the underlying principles behind biological regulation is important for understanding the principles of life, treating complex diseases, and creatingde novosynthetic biology. Buffering - the use of reservoirs of molecules to maintain molecular concentrations - is a widespread and important mechanism for biological regulation. However, a lack of theory has limited our understanding of its roles and quantified effects. Here, we study buffering in energy metabolism using control theory and novel buffer analysis. We find that buffering can enable the simultaneous, independent control of multiple coupled outputs. In metabolism, adenylate kinase and AMP deaminase enable simultaneous control of ATP and adenylate energy ratios, while feedback on metabolic pathways is fundamentally limited to controlling one of these outputs. We also quantify the regulatory effects of the phosphagen system - the above buffers and creatine kinase - revealing which mechanisms regulate which outputs. The results are supported by human muscle and mouse adipocyte data. Together, these results illustrate the synergy of feedback and buffering in molecular biology to simultaneously control multiple outputs.
Long-read cDNA Sequencing Enables a ‘Gene-Like’ Transcript Annotation of Arabidopsis Transposable Elements
Authors: Panda Kaushik , Slotkin R. Keith 
Published: February 2020

AbstractHigh-quality transcript-based annotations of genes facilitates both genome-wide analyses and detailed single locus research. In contrast, transposable element (TE) annotations are rudimentary, consisting of only information on location and type of TE. When analyzing TEs, their repetitiveness and limited annotation prevents the ability to distinguish between potentially functional expressed elements and degraded copies. To improve genome-wide TE bioinformatics, we performed long-read Oxford Nanopore sequencing of cDNAs from Arabidopsis lines deficient in multiple layers of TE repression. We used these uniquely-mapping transcripts to identify the set of TEs able to generate mRNAs, and created a new transcript-based annotation of TEs that we have layered upon the existing high-quality community standard TAIR10 annotation. The improved annotation enables us to test specific standing hypotheses in the TE field. We demonstrate that inefficient TE splicing does not trigger small RNA production, and the cell more strongly targets DNA methylation to TEs that have the potential to make mRNAs. This work provides a transcript-based TE annotation for Arabidopsis, and serves as a blueprint to reduce the genomic complexity associated with repetitive TEs in any organism.
Facilitating women entrepreneurship in Canada: the case of WEKH
Authors: Cukier Wendy , Hassannezhad Chavoushi Zohreh 
Published: February 2020

Purpose
This paper aims to provide a multi-level framework for exploring women entrepreneurship in Canada. The authors examine the Women Entrepreneurship Knowledge Hub (WEKH), a platform to advance women entrepreneurs from diverse backgrounds.

Design/methodology/approach
The authors analyze the major elements associated with the processes and strategies in WEKH through a case study approach.

Findings
The findings presented in this paper clearly show how creating an inclusive innovation ecosystem linking micro-, meso- and macro-level factors has the potential to advance women entrepreneurship

Research limitations/implications
This case study presented here is in the early phase and results are not yet available.

Practical implications
The lessons from WEKH provides a model for other countries.

Social implications
Entrepreneurship drives economic development and gender equality is a critical sustainable development goal. WEKH activities will advance opportunities for women by creating a more inclusive innovation ecosystem.

Originality/value
WEKH is a knowledge hub in Canada that aims to help foster women entrepreneurship in Canada related to the women entrepreneurship strategy national program.
Supply chain quality management and firm performance in China's food industry—the moderating role of social co-regulation
Authors: Hong Jiangtao , Zhou Zhihua , Li Xin , Lau Kwok Hung 
Published: February 2020

PurposeThe purpose of this paper is to investigate the relationships between supply chain quality management (SCQM) and firm performance (including quality safety performance and sales performance) leveraging social co-regulation as a moderator.Design/methodology/approachUsing survey data collected from 203 food manufacturers in China, a series of hierarchical linear modeling analyses were conducted to test hypotheses on the relationships between SCQM and firm performance.FindingsThe findings are threefold. First, all three dimensions of food SCQM practices, i.e., supplier quality management, internal quality management, and customer quality management, have significant positive effects on an enterprise's quality safety performance and sales performance. Second, SCQM practices can also increase sales performance indirectly through quality safety performance as a mediator. Third, while social co-regulation has no significant effect on the relationship between supplier quality management and quality safety performance, it has a significant moderating effect on the relationship between internal quality management and quality safety performance, customer quality management and quality safety performance.Research limitations/implicationsThis study not only integrates SCQM with social co-regulation but also explores the regulating effect of social co-regulation through empirical analysis, thereby providing a theoretical base for future research. However, this research is confined to China and so the results are not necessarily generalizable to other countries.Practical implicationsThe findings inform managers of the importance in enhancing awareness of food quality and safety as well as in improving their sensitivity to salient quality demands of external stakeholders in order to achieve better SCQM practices. The findings can also inform policymakers of the significance in designing a systematic multi-agent cooperation mechanism for food SCQM as well as to build an effective information sharing mechanism for social co-regulation of food safety.Originality/valueThis study contributes to knowledge by empirically examining the relationships of SCQM practices with firm performance. It also expands the scope of SCQM research by incorporating social co-regulation in the study framework.
Negotiating meaning within healthcare to improve suicide prevention
Authors: Doyle Susanna 
Published: February 2020

Purpose
A framework for “negotiating meaning” was applied to a healthcare service to achieve a collaboratively developed suicide prevention clinical pathway.

Design/methodology/approach
The framework was originally developed during a previous study that drew on the theory of philosophical hermeneutics to enable a researcher to better understand the experience of older people. This approach was then applied to a healthcare setting and the development of a suicide prevention clinical pathway. Clinical front-line staff engaged effectively and meaningfully with each other, consumers, family members and management to develop a clinical guideline that reflected best practice and improved care provision. An additional outcome involved establishing a supportive culture in which the shared meanings underpinning the experience of working with people expressing suicidality were explored.

Findings
An evidence-based suicide prevention clinical pathway was developed collaboratively with clinicians taking the lead in the process, and leading to the agreement being reached on the final guideline and processes established. The negotiation process brought the perspectives of the different parties together enabling the sharing of underlying meaning inherent in the experience of losing a consumer tragically to suicide. A commitment to taking joint action to reduce the likelihood of further incidents occurring also grew from the shared understanding that developed.

Originality/value
This paper describes the approach that was applied to facilitate engagement processes between clinicians and service management that also challenged the power differentials that usually exist within healthcare and led to positive engagement that supported the safety and quality agenda.
The application of venture capital strategies tomusharakahfinancing
Authors: Abdul Rahman Aisyah , Mohd Nor Shifa , Salmat Mohd Fadzli 
Published: February 2020

PurposeThis paper aims to explore the strategies used by venture capital (VC) firms in assisting entrepreneurs who have business potential but lack capital. The study also aims to investigate whether the VC strategy can be adopted by Islamic banks throughmusharakahfinancing.Design/methodology/approachApart from content analysis, primary data were gathered from several interview sessions with the management of three VC firms and two Islamic banks.FindingsIslamic banks in Malaysia have great potential to offermusharakahfinancing and mitigate risk by adopting the following five VC strategies: method of selection, channelling of funds, monitoring, non-capital assistance and period of investment. We propose the channelling of corporate social responsibility funds formusharakahfinancing as an initial step in applying VC strategy.Research limitations/implicationsGiven the limited number of willing and eligible respondents in Malaysia, the scope of this study can be widened to a cross-country analysis wheremusharakahfinancing is widely adopted.Practical implicationsThis study motivates regulatory bodies and Islamic banks to considermusharakahfinancing using the risk monitoring strategy adopted from the VC industry.Originality/valueThis study is the first to empirically explore the strategy adopted by VC companies and evaluate whether such a strategy is suitable for the concept ofmusharakahfinancing.
Qualitative analysis to determine decision-makers’ attitudes towards e-government services in a De-Facto state
Authors: Kaya Tuğberk , Sağsan Mustafa , Medeni Tunç , Medeni Tolga , Yıldız Mete 
Published: February 2020

PurposeThe manner in which people, businesses and governments perform is changing because of the spread of technology. Digitalization of governments can be considered a necessity as we are now entering the era of the Internet-of-Things. The advantages and disadvantages of electronic governments have been examined in several research studies. This study aims to examine the attitudes of decision-makers towards e-government. The research aims are as follows: to determine the problems related with e-government usage, to establish the factors which decrease the usage of e-government services and to propose recommendations for the effective application of e-government practices.Design/methodology/approachQualitative research has been used for the study. Participants were chosen by the snowball sampling method, and face-to-face in-depth interviews were conducted with all decision-makers. In-depth interviews are more efficient and enable the acquisition of better qualitative information, in-depth knowledge and statistics, as the distance between the interviewer and interviewee is reduced (Stokes and Bergin, 2006). Questions asked can be categorized under two sections, where the questions in the first section are related to the decision-maker’s management style/managerial proposition, and in the second section, technological questions are asked in terms of the preferred communication method and the decision-makers’ attitudes towards e-government practices.FindingsDecision-makers perceive electronic government to be important, while the level of importance is observed to be different among the decision-makers. Chronic problems exist in many countries, such as nepotism, where the decision-makers have conflicting arguments about e-government and the resulting effect on nepotism. Furthermore, the study also indicates that decision-makers are aware of the importance of mobile government, although they acknowledge that more time is required, as their country is still developing. Electronic voting is also perceived to be important, although the decision-makers believe that security and privacy issues need to be solved before related projects can be initiated.Originality/valueThis research can be a benchmark study for the decision-makers of small island developing states by means of e-government. The impediments preventing the effective application of e-government practices are also discussed in the study. This study will be useful to highlight the triggers and obstacles for e-government development in the context of a developing country. Internet penetration has increased significantly since the 2000s, and therefore, decision-makers need to consider the shift in citizens’ behaviour, such as the high usage of smartphones and the emergence of the Internet-of-Things (Kaya and Bicen, 2016; Kumar et al., 2017).
Witnessing verbal aggression: role of customers’ self-conscious emotions
Authors: Okan Mehmet , Elmadag Ayse Banu 
Published: February 2020

PurposeThis paper aims to examine the widespread effects of service actors’ verbal aggression on witness customers’ intentions toward the service organizations through their self-conscious emotions. The moderating roles of the witness customers’ empathic tendencies and the source of aggression are also examined.Design/methodology/approachIn two scenario-based experiments and by adopting a multifoci approach, severity of mistreatment (aggression vs incivility vs no-mistreatment) and source of mistreatment (employee-to-employee and customer-to-customer) were manipulated to test distinctive effects of witnessing aggression on self-conscious emotions and intentions.FindingsThis study shows that witnessing aggression during service experiences negatively influences customers’ intentions towards the service organization through self-conscious emotions. Moreover, empathic tendencies of customers make these effects more pronounced. It is also shown that witnessing employee-to-employee aggression has a stronger effect on self-conscious emotions and intentions than customer-to-customer aggression.Research limitations/implicationsThis paper uncovers the distinctive effects of aggressive behaviors of service actors on self-conscious emotions from the third-party perspective. It is also shown that empathic tendencies can be detrimental to service organizations in certain conditions.Practical implicationsThe results warn service managers against verbal aggression because of its negative effects on witness customers. It is suggested that they should try to clarify the incident and restore justice in front of the witnesses.Originality/valueThis paper is one of the first attempts to investigate the distinctive effects of witnessing aggression during service experiences and the roles of self-conscious emotions and emphatic tendencies.
The artification of corporate identity: aesthetic convergences of culture and capital
Authors: Bargenda Angela 
Published: February 2020

PurposeThe purpose of this paper is to critically examine the claim that artworks and corporate art collections contribute a qualitative dimension to corporate identity by satisfying aesthetic, social and cultural standards.Design/methodology/approachTo explore the qualitative research purpose, the theoretical framework is supplemented with in-depth interview data from five European banks.FindingsThe findings show that corporate art achieves synergies between culture and capital, internal and external communication and thus offers significant opportunities for innovative marketing communication and identity-building strategies.Practical implicationsThe paper provides insights into how the arts interface with branding-related innovations, assisting managers in long-term decisions on value-based branding and identity construction.Social implicationsIncreased arts engagement by corporations creates new synergies between cultural institutions and corporations through partnerships and philanthropic initiatives.Originality/valueThe originality of the paper is twofold. It thematically explores the under-researched field of art in marketing scholarship. From a methodological point of view, the research design is multidisciplinary and thus delineates new avenues for marketing practice and scholarship.
Internationalisation and branding strategy
Authors: Hinson Robert E. , Osabutey Ellis , Kosiba John Paul , Asiedu Frederick O. 
Published: February 2020

PurposeThe purpose of this study is to analyse how professional football clubs have attained success with internationalisation and branding strategies in foreign markets.Design/methodology/approachBased on an inductive approach, 27 semi-structured interviews were conducted to analyse the perceptions of Ghanaian fans of four English Premier League teams.FindingsThe findings of this study highlight that the strength of professional football brand equity is jointly determined by the level of brand awareness, brand loyalty and perceived quality. However, increasing competition in international markets require professional football clubs to clearly define their marketing strategies to improve how fans perceive them.Originality/valueThis paper is one of the few studies to use country-of-origin paradigm and signalling theory to explain football brand equity building, thereby extending the earlier work of Chanavat and Bodet (2009). Its empirical focus on Africa is also unique and provides evidence to suggest that global marketers have the opportunity to capitalise on market expansion opportunities in developing economies.
Small states and strategic hedging: the United Arab Emirates’ policy towards Iran
Authors: El-Dessouki Ayman , Mansour Ola Rafik 
Published: February 2020

PurposeThe purpose of this paper is to unveil the main changes in the UAE’s policy towards Iran since its foundation in 1971. The UAE favored strategic hedging, extending its commercial and diplomatic relations with Iran, in addition to developing its military capabilities and maintaining military/security alliances with Saudi Arabia and the USA. However, the UAE started to reorient its policy towards Iran by adopting some sort of balancing strategy in the aftermath of the Arab Spring of 2011. This paper examines how and why the UAE had to change course and explores whether it would revert back to strategic hedging with Iran.Design/methodology/approachThe study will be carried out based on a theoretical framework drawn from strategic hedging theory, a new structural theory in international relations, to examine the shifts in UAE policy towards Iran. Previous literature suggests that small states prefer hedging over balancing or bandwagoning. The authors also undertake a descriptive analysis and deploy a longitudinal within-case method to investigate changes in UAE policy towards Iran and identify the causal mechanisms behind these changes. That method allows investigating the impact of a particular event on a case by comparing the same case before and after that event occurred.FindingsThe main finding of this study is that the UAE hedging strategy towards Iran allowed maximizing the political and economic returns from the cooperation with Iran and mitigating the long-range national security risks without breaking up the consistent and beneficial ties with other regional and global powers. Hedging achieved the desired outcome, which is preventing direct military confrontation with Iran. Hard balancing, adopted by Abu Dhabi after the 2011 Arab Spring, has proved to have some negative effects, most importantly provoking Tehran. Some recent indicators suggest, though that the UAE may revert back to its long-established hedging policy towards Iran.Originality/valueStrategic hedging is a new structural theory in international relation, although hedging behavior in states’ foreign policies is far from new. It is new enough, thus, not have been researched sufficiently, strategic hedging still needs theorizing and comparison. This paper highlights the importance of strategic hedging as the most appropriate strategy for small states. It provides an important contribution to the application of the theory to the case of UAE policy towards Iran. The paper also assesses the conventional wisdom that small states prefer hedging over balancing in the light of the changes in the UAE foreign policy since 2011.
Commentary on “depression and people with a learning disability: a way forward”
Authors: McGill Peter 
Published: February 2020

Purpose
The purpose of this paper is to provide a commentary on Andrew Jahoda’s article “Depression and people with a learning disability: a way forward”.

Design/methodology/approach
The paper considers depression and other issues of psychological well-being from the perspective of the eligibility criteria for social care in England as enshrined in the 2014 Care Act.

Findings
There is a danger of issues of psychological well-being being seen as health rather than social care needs. A more integrated perspective is required.

Originality/value
The paper illustrates the importance of the role of social care provision in promoting the well-being of people with learning disabilities.
The adoption of cloud computing in small and medium enterprises: a developing country perspective
Authors: Khayer Abul , Jahan Nusrat , Hossain Md. Nahin , Hossain Md. Yahin 
Published: February 2020

Purpose
The purpose of this paper is to examine the determinants of cloud computing adoption in small and medium enterprises (SMEs), further, to measure the effect of cloud computing adoption on cloud-supported firm performance through enhancing organisational agility.

Design/methodology/approach
The research model is developed by combining two popular theoretical models, namely, the unified theory of acceptance and use of technology (UTAUT) and the technology–organisation–environment (TOE) framework. Data are collected from 372 SMEs to test the model. The strengths of widely used structural equation modelling (SEM) are applied to analyse the data.

Findings
This study reveals that the significant predictors of cloud computing adoption are performance expectancy; effort expectancy; absorptive capacity; data security and privacy; and perceived trust. Also, cloud computing adoption positively influences firm performance directly and through organisational agility. The results of importance–performance map analysis indicate that effort expectancy falls in the critical zone, which needs to be improved.

Originality/value
This research is one of few that blends the strengths of UTAUT and TOE framework. The research outcomes yield noteworthy suggestions to cloud providers, managers and government policymakers on ways of motivating the spread of cloud computing in developing countries.
Citizenship and Unauthorised Migration: a Dialectical Relationship
Authors: Salomon Stefan 
Published: February 2020

AbstractThe relationship between citizenship and immigration law is often conceived as a conceptual dichotomy in which the former functions as the rhetorical domain of inclusion while immigration law does the dirty work of detention, deportation and snooping into peoples’ lives in order to uphold the inclusive values of the internal domain. States however employ a variety of practices of immigration control that infringe citizens’ rights and produce lasting dilatory effects on citizenship itself. Focusing on two specific case studies – racial profiling in identity checks carried out for immigration purposes and the standards of interpretation developed by the European Court of Human Rights in regard to the right to family life in expulsion cases – this article argues that current practices of immigration control result in a transformation of citizenship along racialised lines, which hollows citizenship's normative core of equality and liberty.