bluuebunny/crossref_metadata_2025_split huggingface dataset:
An examination of dysfunctional attitudes and extreme response styles as predictors of relapse in guided internet‐based cognitive behavioral therapy for depression
Authors: Ezawa Iony D. , Forand Nicholas R. , Strunk Daniel R. 
Published: April 2020

AbstractObjectivesInternet‐based cognitive behavioral therapy (iCBT) is an effective treatment option for depression, but its long‐term effects are not well understood. We investigate for whom iCBT may have more enduring effects by evaluating dysfunctional attitudes as predictors of relapse.MethodsThe sample consists of 31 iCBT responders (20 women, average age 31.6) who were followed for 1 year.ResultsHigher Dysfunctional Attitudes Scale scores predicted higher risk of relapse (hazard ratio = 1.98). This relation remained significant when controlling for high style (dysfunctional) or content (functional) responses. Having relatively more positive extreme responses on style rather than content items did not predict risk of relapse.ConclusionsOur results were consistent with the value of differentiating an extreme style of responding from otherwise endorsing belief in dysfunctional attitudes. Research that refines our understanding of patients' individual risk for relapse has the potential to inform how treatment might be individually tailored.
An alumina‐coated UiO‐66 nanocrystalline solid superacid with high acid density as a catalyst for ethyl levulinate synthesis
Authors: Zhang Zhi , Yuan Hong 
Published: April 2020

AbstractBACKGROUNDThe zirconium‐containing metal–organic framework (MOF) UiO‐66 was used as a cell to synthesize SO42−/ZrO2@Al2O3, a high‐density superacid with relatively strong Brønsted acidity. The UiO‐66 MOF was first coated with alumina to form ZrO2@Al2O3. Impregnation with ammonium sulfate and calcination at 500 °C afforded the bimetallic composite solid superacid SO42−/ZrO2@Al2O3.RESULTSScanning and transmission electron microscopy images confirmed that UiO‐66 was successfully coated with aluminium oxide, and its octahedral structure and uniform size (400–600 nm) were retained. SO42−/ZrO2@Al2O3 had a Brunauer–Emmett–Teller specific surface area of 301–330 m2 g−1 and average pore diameter of 9.6–10.7 nm. X‐ray photoelectron spectroscopy and Fourier transform infrared analysis showed that SO42−/ZrO2@Al2O3 contained S6+ and Al3+. Temperature‐programmed ammonia desorption analysis showed that SO42−/ZrO2@Al2O3 contained super‐strong acid sites. The total volume of desorbed ammonia reached 90–109 cm3 g−1. Infrared spectra of adsorbed pyridine indicated that SO42−/ZrO2@Al2O3 contained mainly Lewis acid sites and was relatively rich in Brønsted acid sites. Thermogravimetric analysis showed that the thermal stability of SO42−/ZrO2@Al2O3 was high.CONCLUSIONSSO42−/ZrO2@Al2O3‐3M (the impregnation concentration of ammonium sulfate was 3 mol L−1) and glucose were used to synthesize ethyl levulinate (EL) in ethanol. The highest EL yield of 37.5 mol% was obtained after reacting the mixture at 200 °C for 5 h. An EL yield of 28.8 mol% was obtained after four consecutive reuses of the SO42−/ZrO2@Al2O3‐3M catalyst. © 2020 Society of Chemical Industry
Potential of live pathogen vaccines for defeating the COVID‐19 pandemic: History and mechanism
Authors: Chen Ji‐Wang , Chen Ji‐Ming 
Published: April 2020

AbstractThe whole world has entered a terrible crisis with a huge and increasing number of human deaths and economic losses in fighting the pandemic of COVID‐19 caused by the novel coronavirus termed SARS‐CoV‐2. The live pathogen vaccine (LPV) strategy, which originated in ancient China for fighting smallpox, has been applied successfully by US military recruits for decades to control acute respiratory diseases caused by types 4 and 7 adenoviruses. This strategy has also been widely employed in veterinary medicine. These facts suggest a fast way out of the current pandemic crisis, namely that SARS‐CoV‐2 could be directly used as a live vaccine. Beyond the two traditional mechanisms to guarantee the LPV's safety (the LPV seed strain is properly selected; the LPV is inoculated bypassing the respiratory sites of pathology), three novel mechanisms to further ensure the LPV's safety are available (the virus replication is inhibited with early use of an antiviral drug; symptomatic LPV recipients are cured with convalescent plasma; the LPV is inoculated in the hot season). This LPV strategy has multiple potential advantages over other options and could reduce morbidity and mortality greatly as well as the economic loss caused by the pandemic. The safety and efficacy of this strategy should be investigated strictly using animal experiments and clinical trials, and even if the experiments and trials all support the strategy, it should be implemented with enough caution.
Teachers’ Perceptions of Students’ Creativity in China’s Classrooms: The Role of Students’ Academic Achievement and Misbehaviors
Authors: Guo Jiajun , Tong Yao , Pang Weiguo 
Published: April 2020

AbstractTeachers can be biased, especially toward low achievers and students with behavioral issues. However, creative students often appear to be disruptive in the classroom, and many of them struggle academically. The purpose of the present study was to examine the extent to which teachers’ perceptions of students’ creativity is associated with students’ academic achievement and classroom (mis)behaviors, as well as to examine the interaction between these two factors. Three hundred and fifty‐four eighth‐grade students selected from five middle schools in China participated in this study. Using achievement scores, peer nominations, a divergent thinking test, a self‐rated ideational behavior scale, and teacher ratings, the present study found that, whereas creativity has no significant relationship with teachers’ perceptions, academic achievements and misbehavior are significantly associated within structors’ perceptions. The achievement bias resulted in the underestimation of low achievers’ creativity, even when the low achievers were highly creative. More nuances emerged when student misbehaviors were considered. Specifically, misbehaving low achievers’ originality was further underestimated even when they were highly original. In contrast, teachers overestimated well‐behaved high achievers’ creativity, even when the students comprised the lowest creativity group. The results are further discussed from a socio‐cultural perspective.
Common institutional investors and supplier performance in supply chains
Authors: Cheung Yan‐Leung , Haw In‐Mu , Hu Bingbing , Swink Morgan , Zhang Wenlan 
Published: April 2020

AbstractWe investigate how common institutional investors (CIIs) in supply chains affect supplier performance. Social network theory suggests that buyer–supplier relationships are influenced by networks of ties in which they are embedded. While prior research has concentrated on networks of trade interactions, we instead examine the influences of networks through common investors. Utilizing a large sample of buyer–supplier relationships, we find that the presence of CIIs improves suppliers' operating and market performance, especially for suppliers with greater dependence on buyers. In addition, supplier performance increases with the common ownership stakes held by CIIs, but decreases with the asymmetric ownership stakes of CIIs across supply chain partners. We find that better financial collaboration between the partners appears to be a mechanism through which CIIs enhance supplier performance. Lastly, we find that the role of CIIs in strengthening supplier performance is distinct from that of direct equity links. Collectively, our findings highlight a novel role of indirect cross‐ownership in fostering supply chain collaboration and coordinating vertical relationships and, in turn, improving supplier performance.
1,3,5‐Triethynylbenzene and melamine as monomers to synthesize three‐dimensional network porous aromatic frameworks based silica/florisil for determination of carbendazim and thiabendazole in spinach
Authors: Sun Liping , Wang Sufang , Zhu Tao 
Published: April 2020

AbstractIn this study, the new and efficient three‐dimensional network porous aromatic frameworks materials called Silica‐PAFs‐a, Florisil‐PAFs‐a, Silica‐PAFs‐b, and Florisil‐PAFs‐b were first synthesized. The properties of materials were analyzed by five characterization methods. The materials were used as adsorbents in pipette‐tip solid‐phase extraction for the effective determination of carbendazim and thiabendazole in spinach sample. Meanwhile, the obtained materials were tested by static adsorption and dynamic adsorption. The result showed that the specific surface area of materials greatly increased after introducing three‐dimensional network porous aromatic frameworks. Microstructural modification exposed a large number of amino reactive groups that made them have a better adsorption amount for the two targets. The calibration graphs of carbendazim and thiabendazole in methanol were linear over 0.10–300.0 µg/mL, and the limits of detection and quantification were 0.00546 and 0.0182 µg/mL, and 0.00741 and 0.0247µg/mL respectively. A reliable analytical method was developed for recognition targets in spinach sample by Silica‐PAFs‐b with satisfactory extraction recoveries (96.25 and 100.51%). The proposed method using the material was applied for trace analysis of the carbendazim and thiabendazole residue.
Value of High‐Frequency Ultrasound in Accurate Staging of Mycosis Fungoides/Sézary Syndrome
Authors: Wang Yukun , Niu Zihan , Liu Jie , Zhu Qingli , Liu Zhaorui , Liu Yuehua , Jin Hongzhong 
Published: April 2020

ObjectivesThis study was aimed to assess the ultrasound (US) characteristics of mycosis fungoides (MF)/Sézary syndrome (SS) and explore the value of high‐frequency US in accuracy staging for classic mycosis fungoides (cMF).MethodsA prospective study was designed. Twenty‐six patients with histopathologically confirmed MF or SS were enrolled to undergo HF‐US examinations. Both 50‐ and 20‐MHz US images of the most prominent lesion of each patient were collected by a cutaneous diagnostic US system, and the US characteristics in different stages were analyzed by 2 physicians independently. The Fisher exact test was used for the statistical analysis.ResultsA total of 26 patients underwent this study, including 23 with cMF, 2 with folliculotropic mycosis fungoides (FMF), and 1 with SS. Among cMF, 16 patients with patches or plaques (the early‐stage group) showed a subepidermal low‐echogenic band, and only 3 lesions in the plaque stage partially extended to the superficial dermis. Seven patients with tumors (the advanced‐stage group) showed lesions that infiltrated to the deep dermis or subcutaneous tissue. The infiltration depth (P < .001), clarity of the boundary (P = .002), and homogeneity of internal echoes (P = .001) were significantly different between the early and advanced stages. Additionally, the 2 FMF lesions and 1 SS lesion had characteristic manifestations, showing a well‐defined subepidermal low‐echogenic band with patchy hypoechoic regions around the hair follicles in the dermis.ConclusionsHigh‐frequency US can be used to accurately detect the infiltration depth and morphologic features of MF/SS lesions and provide important information for tumor staging of cMF. Additionally, the characteristic US features in FMF and SS might be helpful for diagnosis.
Theoretical and Kinetic Analysis of the Esterification of Undecylenic Acid with Glycerol
Authors: Fabre Jean‐François , Boussambe Gildas Nyame Mendendy , Valentin Romain , Mouloungui Zéphirin 
Published: April 2020

AbstractThe synthesis of undecylenic acid partial esters can be performed at mild temperature with a classical esterification reaction catalyzed by dodecylbenzene sulfonic acid (DBSA). A semi‐empirical molecular modeling on the different reaction intermediates indicates that DBSA can strongly decrease their heats of formation through hydrogen bonding. Diester formation seems to be thermodynamically favored with a selectivity for alpha, alpha, or alpha, beta forms that depend on the geometry of the catalyst‐intermediate configuration. Triesters are not favored but a high selectivity for monoesters requires a kinetic control. Experimental approach, considering different DBSA concentrations and temperature partially confirms the theoretical predictions but surfactant properties of DBSA and monoesters may induce nonpredicted geometries. Global apparent activation energies are calculated, corresponding to the formation and hydrolysis of mono and diesters. If water trapping allows the decrease of hydrolysis reaction constants, the presence of water and subsequent phase separation may explain differences between theoretical and experimental results and could help increasing monoester selectivity.
Heterologous expression of the gene for chlorite dismutase from Ideonella dechloratans is induced by an FNR‐type transcription factor
Authors: Rova Maria , Hellberg Lindqvist Miriam , Goetelen Thijs , Blomqvist Shady , Nilsson Thomas 
Published: April 2020

AbstractRegulation of the expression of the gene for chlorite dismutase (cld), located on the chlorate reduction composite transposon of the chlorate reducer Ideonella dechloratans, was studied. A 200 bp upstream sequence of the cld gene, and mutated and truncated versions thereof, was used in a reporter system in Escherichia coli. It was found that a sequence within this upstream region, which is nearly identical to the canonical FNR‐binding sequence of E. coli, is necessary for anaerobic induction of the reporter gene. Anaerobic induction was regained in an FNR‐deficient strain of E. coli when supplemented either with the fnr gene from E. coli or with a candidate fnr gene cloned from I. dechloratans. In vivo transcription of the suggested fnr gene of I. dechloratans was demonstrated by qRT‐PCR. Based on these results, the cld promoter of I. dechloratans is suggested to be a class II‐activated promoter regulated by an FNR‐type protein of I. dechloratans. No fnr‐type genes have been found on the chlorate reduction composite transposon of I. dechloratans, making anaerobic upregulation of the cld gene after a gene transfer event dependent on the presence of an fnr‐type gene in the recipient.
ARNT‐dependent CCR8 reprogrammed LDH isoform expression correlates with poor clinical outcomes of prostate cancer
Authors: Chen Guo , Cai Zhi‐duan , Lin Zhuo‐yuan , Wang Cong , Liang Yu‐xiang , Han Zhao‐dong , He Hui‐chan , Mo Ru‐jun , Lu Jian‐ming , Pan Bin , Wu Chin‐lee , Wang Fen , Zhong Wei‐de 
Published: April 2020

AbstractLactate dehydrogenase isozyme (LDH) is a tetramer constituted of two isoforms, LDHA and LDHB, the expression of which is associated with cell metabolism and cancer progression. Our previous study reveals that CC‐chemokine ligand‐18 (CCL18) is involved in progression of prostate cancer (PCa).This study aims to investigate how CCL18 regulates LDH isoform expression, and therefore, contributes to PCa progression. The data revealed that the expression of LDHA was upregulated and LDHB was downregulated in PCa cells by CCL18 at both messenger RNA and protein levels. The depletion of CCR8 reduced the ability of CCL18 to promote the proliferation, migration, and lactate production of PCa cells. Depletion of a CCR8 regulated transcription factor, ARNT, significantly reduced the expression of LDHA. In addition, The Cancer Genome Atlas dataset analyses revealed a positive correlation between CCR8 and ARNT expression. Two dimension difference gel electrophoresis revealed that the LDHA/LDHB ratio was increased in the prostatic fluid of patients with PCa and PCa tissues. Furthermore, increased LDHA/LDHB ratio was associated with poor clinical outcomes of patients with PCa. Together, our results indicate that the CCR8 pathway programs LDH isoform expression in an ARNT dependent manner and that the ratio of LDHA/LDHB has the potential to serve as biomarkers for PCa diagnosis and prognosis.
Development of a real‐time indoor location system using bluetooth low energy technology and deep learning to facilitate clinical applications
Authors: Tang Guanglin , Yan Yulong , Shen Chenyang , Jia Xun , Zinn Meyer , Trivedi Zipalkumar , Yingling Alicia , Westover Kenneth , Jiang Steve 
Published: April 2020

PurposeAn indoor, real‐time location system (RTLS) can benefit both hospitals and patients by improving clinical efficiency through data‐driven optimization of procedures. Bluetooth‐based RTLS systems are cost‐effective but lack accuracy because Bluetooth signal is subject to significant fluctuation. We aim to improve the accuracy of RTLS using the deep learning technique.MethodsWe installed a Bluetooth sensor network in a three‐floor clinic building to track patients, staff, and devices. The Bluetooth sensors measured the strength of the signal broadcasted from Bluetooth tags, which was fed into a deep neural network to calculate the location of the tags. The proposed deep neural network consists of a long short‐term memory (LSTM) network and a deep classifier for tracking moving objects. Additionally, a spatial‐temporal constraint algorithm was implemented to further increase the accuracy and stability of the results. To train the neural network, we divided the building into 115 zones and collected training data in each zone. We further augmented the training data to generate cross‐zone trajectories, mimicking the real‐world scenarios. We tuned the parameters for the proposed neural network to achieve relatively good accuracy.ResultsThe proposed deep neural network achieved an overall accuracy of about 97% for tracking objects in each individual zone in the whole three‐floor building, 1.5% higher than the baseline neural network that was proposed in an earlier paper, when using 10 s of signals. The accuracy increased with the density of Bluetooth sensors. For tracking moving objects, the proposed neural network achieved stable and accurate results. When latency is less of a concern, we eliminated the effect of latency from the accuracy and gained an accuracy of 100% for our testing trajectories, significantly improved from the baseline method.ConclusionsThe proposed deep neural network composed of a LSTM, a deep classifier and a posterior constraint algorithm significantly improved the accuracy and stability of RTLS for tracking moving objects.
Daily grip strength response to intravenous immunoglobulin in chronic immune neuropathies
Authors: Doneddu Pietro E. , Hadden Robert D.M. 
Published: April 2020

AbstractIntroductionMonitoring grip strength at home may detect improvement between intravenous immunoglobulin (IVIg) treatments in patients with chronic inflammatory neuropathies (CINs).MethodsFifteen patients recorded grip strength each day, from one IVIg treatment until the next. We analyzed grip strength changes comparing thresholds of 8 kPa and 14 kPa. “Random” fluctuations of grip strength were distinguished from treatment response by smoothing the data.Results“Random” fluctuations of at least 8 kPa occurred in 27% of patients. Smoothed daily grip strength increased by at least 8 kPa above baseline in 11 (73%) patients. Grip strength increased by at least 8 kPa for 3 consecutive days in 9 (60%) patients, and 5‐day block mean increased by at least 8 kPa in 10 (67%) patients.DiscussionHome monitoring of grip strength confirmed treatment response in most patients with CINs on IVIg. To detect improvement in an individual patient, we suggest a threshold of at least 8 kPa on 3 consecutive days or on 5‐day block mean.
Bones in Stasis: The Challenging History and Uncertain Future of the Virginia State Penitentiary Collection
Authors: Chapman Ellen , Cook Libby , Edwards Ana 
Published: April 2020

AbstractThis article describes an archeological ethnographic study of the history and social context of the Virginia State Penitentiary, where burials excavated in the 1990s still remain in limbo: unpublished, unmemorialized, and unmourned. The penitentiary (1804–1991) was a feared site of solitary confinement, carceral labor, and capital punishment. Fieldwork conducted in advance of the penitentiary’s demolition recorded solitary confinement cells within the eighteenth‐century foundations, but also discovered a substantial burial ground within the prison walls. The collection includes the remains of over 200 people, many of whom were black prisoners who died between 1878 and 1884. Unfortunately, archeological analysis and publication were never completed. This article presents a new public engagement process to identify fresh possibilities for the sites and the individuals represented in this collection. Based on over thirty semistructured interviews conducted in 2015 and data from over 230 respondents to the 2018 Richmond Penitentiary Survey, we discuss how the penitentiary remains resonate or fails to resonate with Richmond residents, even as the city’s broader history of archeological neglect is becoming better understood. We discuss how archival research and emerging models for archeological restorative justice may provide new avenues for addressing this urban archeological erasure in a major Southern metropolis.
Paleodiet and health in a mass burial population: The stable carbon and nitrogen isotopes from Potočani, a 6,200‐year‐old massacre site in Croatia
Authors: McClure Sarah B. , Zavodny Emily , Novak Mario , Balen Jacqueline , Potrebica Hrvoje , Janković Ivor , Kennett Douglas J. 
Published: April 2020

AbstractThis paper presents the results of carbon and nitrogen stable isotope analyses on human remains uncovered from Potočani, a Copper Age (Eneolithic) mass burial site in continental Croatia. The remains of at least 41individuals were uncovered in a pit in 2007 during rescue excavations in Požeško‐Slavonska county. Skeletal evidence of violence and the disorganized arrangement of bodies suggest that burial took place over a short period of time. Radiocarbon dates and associated ceramics indicate these people were part of the Lasinja cultural group, dating to the Middle Copper Age (ca.4200 cal BC). Carbon and nitrogen stable isotope analyses on 40individuals indicate higher than expected nitrogen values in comparison with other regional populations and significant differences between children, juveniles, and adults at the site of Potočani. Bioarchaeological and stable isotope results support the interpretation that the people buried at Potočani likely experienced dietary stress in the years leading up to their violent deaths.
From Interaction to Function in DNA‐Templated Supramolecular Self‐Assemblies
Authors: Surin Mathieu , Ulrich Sébastien 
Published: April 2020

AbstractDNA‐templated self‐assembly represents a rich and growing subset of supramolecular chemistry where functional self‐assemblies are programmed in a versatile manner using nucleic acids as readily‐available and readily‐tunable templates. In this review, we summarize the different DNA recognition modes and the basic supramolecular interactions at play in this context. We discuss the recent results that report the DNA‐templated self‐assembly of small molecules into complex yet precise nanoarrays, going from 1D to 3D architectures. Finally, we show their emerging functions as photonic/electronic nanowires, sensors, gene delivery vectors, and supramolecular catalysts, and their growing applications in a wide range of area from materials to biological sciences.