bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Isolated and Combined Ingestion of Sodium Bicarbonate and β-Alanine on Combat Sports Athletes' Performance: A Systematic Review
Authors: Lopes-Silva João Paulo , Franchini Emerson 
Published: October 2020

ABSTRACT
This systematic review analyzed the isolated and combined effects of sodium bicarbonate (NaHCO3) and beta-alanine (β-alanine) supplementation on combat sports athletes' performance. Using the PRISMA guidelines, studies were identified through 3 databases and only 10 articles were included, 6 investigated the isolated ingestion of NaHCO3, 3 investigated isolated ingestion of β-alanine, whereas only 1 investigated the coingestion of NaHCO3 and β-alanine on combat sports performance. The results showed that both acute isolated ingestion and chronic isolated ingestion of NaHCO3 and chronic β-alanine are effective to improve combat sports athletes' performance and the coingestion of β-alanine and NaHCO3 resulted in additional improvements.
Optimizing Exercise Selection for the Asymmetric Athlete After Anterior Cruciate Ligament Reconstruction
Authors: Ogborn Dan 
Published: October 2020

ABSTRACT
Persistent deficits in quadriceps strength occur after anterior cruciate ligament (ACL) reconstruction and should be addressed to facilitate safe return to sport. Asymmetric movement patterns that shield the affected knee by shifting demands to the unaffected lower extremity, or other joints within the affected limb, may limit the ability of common strength training exercises to effectively mitigate quadriceps weakness. A multifaceted approach focusing on the early restoration of symmetrical loading during the squat, programming isolated knee extensions, and varying exercise selection to include split-stance positions, such as the split-squat and lunge, may result in the successful restoration of quadriceps strength after ACL reconstruction.
Lessons Learned from the COVID-19 Pandemic and Their Possible Consequences on Manufacturing
Authors: Monostori László , Váncza József 
Published: October 2020

Abstract
Manufacturing became one of the main targets of the coronavirus disease 2019 pandemic. Important questions such as how to deal with the drastic changes (up and down) in demand, and how to keep production ongoing with a decimated workforce and crippled supply chains arose. This technical note gives a short assessment of the praiseworthy reactions of the manufacturing industry, which prevented society from sinking into an even deeper crisis. The pandemic, at the same time, pointed out some weaknesses of present-day manufacturing. Possible long-term consequences of the lessons given and perhaps learned are summarized herein, with a focus on substantial changes and new paradigms that could provide an appropriate armory for the manufacturing industry when responding to similar or even more drastic situations in the future. However, it is yet undecided as to whether the ongoing changes in manufacturing will be accelerated or dismissed, causing manufacturers to fall back into the old groove. Some related questions and dilemmas are also exposed in the end of the paper.
Prenatal Opioid Exposure Enhances Responsiveness to Future Drug Reward and Alters Sensitivity to Pain: A Review of Preclinical Models and Contributing Mechanisms
Authors: Grecco Gregory G. , Atwood Brady K. 
Published: October 2020

AbstractThe opioid crisis has resulted in an unprecedented number of neonates born with prenatal opioid exposure (POE); however, the long-term effects of POE on offspring behavior and neurodevelopment remain relatively unknown. The advantages and disadvantages of the various preclinical POE models developed over the last several decades are discussed in the context of clinical and translational relevance. Although considerable and important variability exists among preclinical models of POE, the examination of these preclinical models has revealed that opioid exposure during the prenatal period contributes to maladaptive behavioral development as offspring mature including an altered responsiveness to rewarding drugs and increased pain response. The present review summarizes key findings demonstrating the impact of POE on offspring drug self-administration (SA), drug consumption, the reinforcing properties of drugs, drug tolerance, and other reward-related behaviors such as hypersensitivity to pain. Potential underlying molecular mechanisms which may contribute to this enhanced addictive phenotype in POE offspring are further discussed with special attention given to key brain regions associated with reward including the striatum, prefrontal cortex (PFC), ventral tegmental area (VTA), hippocampus, and amygdala. Improvements in preclinical models and further areas of study are also identified which may advance the translational value of findings and help address the growing problem of POE in clinical populations.
Biological Action Identification Does Not Require Early Visual Input for Development
Authors: Rajendran Siddhart S. , Bottari Davide , Shareef Idris , Pitchaimuthu Kabilan , Sourav Suddha , Troje Nikolaus F. , Kekunnaya Ramesh , Röder Brigitte 
Published: October 2020

AbstractVisual input during the first years of life is vital for the development of numerous visual functions. While normal development of global motion perception seems to require visual input during an early sensitive period, the detection of biological motion (BM) does not seem to do so. A more complex form of BM processing is the identification of human actions. Here, we tested whether identification rather than detection of BM is experience dependent. A group of human participants who had been treated for congenital cataracts (CC; of up to 18 years in duration, CC group) had to identify ten actions performed by human line figures. In addition, they performed a coherent motion (CM) detection task, which required identifying the direction of CM amid the movement of random dots. As controls, developmental cataract (DC) reversal individuals (DC group) who had undergone the same surgical treatment as CC group were included. Moreover, normally sighted controls were tested both with vision blurred to match the visual acuity (VA) of CC individuals [vision matched (VM) group] and with full sight [sighted control (SC) group]. The CC group identified biological actions with an extraordinary high accuracy (on average ∼85% correct) and was indistinguishable from the VM control group. By contrast, CM processing impairments of the CC group persisted even after controlling for VA. These results in the same individuals demonstrate an impressive resilience of BM processing to aberrant early visual experience and at the same time a sensitive period for the development of CM processing.
Effects of iodine supplementation during pregnancy on pregnant women and their offspring: a systematic review and meta-analysis of trials over the past 3 decades
Authors: Nazeri Pantea , Shariat Mamak , Azizi Fereidoun 
Published: October 2020

Objective
The current systematic review aimed to provide comprehensive data on the effects of iodine supplementation in pregnancy and investigate its potential benefits on infant growth parameters and neurocognitive development using meta-analysis.

Methods
A systematic review was conducted on trials published from January 1989 to December 2019 by searching MEDLINE, Web of Science, the Cochrane Library, Scopus, and Google Scholar. For most maternal and neonatal outcomes, a narrative synthesis of the data was performed. For birth anthropometric measurements and infant neurocognitive outcomes, the pooled standardized mean differences (SMDs) with 95% CIs were estimated using fixed/random effect models.

Results
Fourteen trials were eligible for inclusion in the systematic review, of which five trials were included in the meta-analysis. Although the findings of different thyroid parameters are inconclusive, more consistent evidence showed that iodine supplementation could prevent the increase in thyroglobulin concentration during pregnancy. In the meta-analysis, no differences were found in weight (−0.11 (95% CI: −0.23 to 0.01)), length (−0.06 (95% CI: −0.21 to 0.09)), and head circumference (0.26 (95% CI: −0.35 to 0.88)) at birth, or in cognitive (0.07 (95% CI: −0.07 to 0.20)), language (0.06 (95% CI: −0.22 to 0.35)), and motor (0.07 (95% CI: −0.06 to 0.21)) development during the first 2 years of life in infants between the iodine-supplemented and control groups.

Conclusion
Iodine supplementation during pregnancy can improve the iodine status in pregnant women and their offspring; however, according to our meta-analysis, there was no evidence of improved growth or neurodevelopmental outcomes in infants of iodine-supplemented mothers.
A Conserved NRDE-2/MTR-4 Complex Mediates Nuclear RNAi in Caenorhabditis elegans
Authors: Wan Gang , Yan Jenny , Fei Yuhan , Pagano Daniel J , Kennedy Scott 
Published: October 2020

Abstract
Small regulatory RNAs such as siRNAs regulate splicing, transcription, and genome integrity in many eukaryotes. In Caenorhabditis elegans, siRNAs bind nuclear Argonautes, which interact with homologous.....
¿En octubre no hay milagros es una novela de tesis fallida por la ideología representada?
Authors: Babilonia Carlos Lhoid Margarita 
Published: October 2020

La novela de Oswaldo Reynoso, En octubre no hay milagros (1965), ha recibido críticas por su lenguaje exagerado y la representación hiperbolizada de sus protagonistas. Sin embargo, sobre la intencionalidad del mensaje y su fuerte carga ideológica se ha explorado poco; no obstante presentar contraposición de los espacios urbano-marginales, el cuestionamiento de ideología del sujeto dominante, la participación continua de la voz del narrador, el lenguaje diferenciador y la crítica mordaz hacia la sociedad peruana, elementos propios de una novela de tesis, no forma parte de esta clasifcación. Esto se evidencia en la falta de prólogo que sustenta la importancia de una ideología defendida en el texto; además, carece de una propuesta o solución para luchar contra la realidad adversa. Por eso, este estudio propone explicar si acaso se puede considerar esta obra como una novela de tesis fallida.
Efficacy and Safety of The Herbal Combination Containing Tropaeoli Majoris Herba and Armoraciae Rusticanae Radix in Patients Suffering from Uncomplicated, Acute Rhinosinusitis: A Randomized, Double-Blind, Placebo Controlled, Two-Arm, Parallel Group, Phase
Authors: Albrecht Uwe , Stangeb Rainer , Schermuly Nadine 
Published: October 2020

Objectives: Demonstration of the efficacy and safety of an herbal combination containing horseradish root and nasturtium herb for the treatment of uncomplicated, acute rhinosinusitis.
Design: Randomized, double-blind, placebo-controlled, two-arm, parallel group, multicenter, phase IV clinical study.
Setting: Sixteen centers in Germany, from October 2017 to March 2018.
Participants: Adult patients (≥18 – 75 years, male and female) diagnosed with uncomplicated, acute rhinosinusitis.
Interventions: Participants received the herbal combination or placebo (3 x 4 per day) for 14 days.
Clinical trial registration: EudraCT 2017-002081-40.
Endpoints: Primary endpoint was MRSSinv/MRSSpat documented between day 6 and day 10, computed as AUC, assessed by ANCOVA with day 3 as covariate. MRSSinv/MRSSpat, responder rates, efficacy assessment and SNOT-20 GAV were used as secondary endpoints.
Results: Out of 380 randomized participants, 238 were included in the FAS for statistical analysis. Treatment with the herbal combination revealed a significant smaller AUC (14.99) compared to placebo (18.52, p=0.0003). Moreover, MRSSinv/MRSSpat was significantly lower after administration of the herbal combination in comparison to placebo (3.60 herbal combination vs. 4.40 placebo, p=0.0018). Responder rates were significantly higher at visit 3 of patients receiving the herbal combination compared to placebo (92.1% herbal combination vs. 83.3% placebo, p=0.0418). Adverse events occurred in 21.9% and 18.6% of participants receiving the herbal combination and placebo, respectively. Most common adverse events were headaches and gastrointestinal complaints.
Conclusion: Efficacy and safety of the herbal combination in comparison to placebo were confirmed while the treatment was well tolerated.
Isolation and molecular identification of Aeromonas species from the tank water of ornamental fishes
Authors: Cheok Yi Ying , Puah Suat Moi , Chua Kek Heng , Tan Jin Ai Mary Anne 
Published: October 2020

AbstractAeromonads are recognised as important pathogens of fishes. In this study, ten water samples were randomly collected from pet shops' fish tanks and home aquaria inhabited by several fish species (silver arowana, koi, goldfish, catfish, pictus fish, silver shark and silver dollar fish). Altogether 298 colonies were isolated using Aeromonas selective agar. A total of 154 isolates were then confirmed as belonging to the genus Aeromonas using the GCAT gene. Using ERIC-PCR, a total of 40 duplicate isolates were excluded from the study and 114 isolates were subjected to PCR-RFLP targeting the RNA polymerase sigma factor (rpoD) gene using lab-on-chip. A total of 13 different Aeromonas species were identified. The most prevalent species were A. veronii (27%, 31/114), followed by A. dhakensis (17%, 19/114), A. finlandiensis (9%, 10/114), A. caviae (8%, 9/114), A. hydrophila (4%, 4/114), A. jandaei (4%, 4/114), A. rivuli (3%, 3/114), A. enteropelogens (2%, 2/114), A. tecta (2%, 2/114), A. allosaccharophila (1%, 1/114), A. eucrenophila (1%, 1/114), A. media (1%, 1/114) and A. diversa (1%, 1/114). Twenty-six isolates (23%) were unidentifiable at species level. The present study demonstrates that Aeromonas species are highly diverse in freshwater fish tanks, and suggests the potential risks posed by the isolated bacteria to the health of ornamental fish species.
MoCA as a cognitive assessment tool for absence status epilepticus
Authors: Rodrigues Sofia Grenho , Gouveia Raquel Gil , Bentes Carla 
Published: October 2020

ABSTRACTDe novo absence status is clinically characterized by a confusional syndrome and neurophysiologically by the presence of periodic spike/polyspike‐and‐wave discharges on EEG. The treatment should be started promptly, and fast recovery is usually seen. However, cognitive symptoms can be very difficult to detect, and no consensus exists on how cognitive improvement can be clinically monitored. We report a patient with absence status epilepticus, whose therapeutic response was monitored neurophysiologically with EEG and clinically with a cognitive test; the Montreal Cognitive Assessment (MoCA). Based on this case report, we describe the use of the MoCA for monitoring cognitive function in a patient with absence status epilepticus. MoCA was evaluated on three occasions, with a total score ranging from 9, before treatment, to 23, when an EEG with no epileptiform discharges was obtained. We suggest that MoCA may be a useful tool to monitor cognitive improvement in absence status epilepticus.
ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ ДИСТАНЦИОННОГО ОБУЧЕНИЯ В СОВРЕМЕННОЙ РОССИЙСКОЙ ВЫСШЕЙ ШКОЛЕ
Authors: Бушуев Игорь Венальевич , Нектаревская Юлия Борисовна , Толстокора Олег Николаевич 
Published: October 2020

Целью исследования является анализ существующих проблем в сфере современного вузовского дистанционного образования и определение перспектив развития дистанционного обучения в высших учебных заведениях с учетом опыта применения соответствующих методик в период пандемии коронавируса в 2020 г. в России, их достоинств и недостатков, выделяемых на основе изучения отношения к ним со стороны профессорско-преподавательского состава и студентов.
Методологическую основу исследования составляют системный, синергетический, кибернетический, личностно-ориентированный, компетентностный подходы к проблеме дистанционного обучения студентов в высших учебных заведениях. Теоретической основой послужили положения специалистов в области применения дистанционных образовательных технологий в образовании. В качестве источниковой базы использовались нормативно-правовые акты в области образования, монографии, материалы конференций, диссертационные исследования, а также материалы всероссийских социологических исследований, посвященных отношению преподавателей и студентов к различным аспектам дистанционного обучения.
Результаты исследования. Опыт активного применения дистанционных методов обучения в современной российской высшей школе в период пандемии 2020 г. свидетельствует о наличии наряду с определенными достоинствами существенных недостатков системы дистанционного обучения, на что явно указывают результаты эмпирических исследований, проведенных в ряде ведущих отечественных университетов. Основными субъектами образовательного процесса качество дистанционного обучения в целом оценивается как более низкое по сравнению с традиционными методиками: многими респондентами, в частности, было отмечено в качестве существенного недостатка дистанционного обучения отсутствие прямого визуального контакта и непосредственного взаимодействия преподавателя со студентами, что обуславливает невозможность осуществления контроля за поведением обучающихся во время занятий и экзаменов. Кроме того, серьезным изъяном дистанционного обучения является отсутствие возможности осуществлять эффективное воспитательное воздействие на обучающихся, что также является значимой целью учебного процесса в вузах. В силу этих причин дистанционное обучение призвано не замещать, а дополнять и обогащать существующие форматы взаимодействия студентов и преподавателей.
Перспективу исследования составляет дальнейшее социологическое исследование приобретаемого опыта применения дистанционного обучения в современных российских университетах с целью определения оптимального соотношения используемых технологий обучения, совершенствования вузовских образовательных программ и улучшения информационного ресурсного обеспечения учебного процесса.
СОЦИОКУЛЬТУРНЫЕ ОСНОВАНИЯ ЭСТЕТИЧЕСКОГО ВОСПИТАНИЯ ПЕДАГОГОВ ТВОРЧЕСКИХ СПЕЦИАЛЬНОСТЕЙ
Authors: Самыгин Сергей Иванович , Загутин Дмитрий Сергеевич , Шилина Наталья Анатольевна 
Published: October 2020

Цель статьи — обоснование необходимости учитывать социокультурные основания эстетического воспитания при формировании педагогов творческих специальностей.
Методологические основания исследования составляют общенаучные принципы объективности, системности и историчности, находящие свое применение в широком пространстве общественного и гуманитарного знания.
Результаты исследования. Эстетическое воспитание педагогов творческих специальностей представляет собой элемент освоения культуры, но подразумевает определенную специфику, связанную с особенностями будущей профессиональной деятельности. Эстетическое воспитание будущих педагогов подразумевает формирование эстетической культуры как интегральной части личности педагога. Освоение эстетической культуры педагогами творческих специальностей подразумевает не только знаниевую, но и практическую составляющую и базируется на нескольких выделенных принципах. Социокультурные основания выступают в качестве необходимого фундамента эстетического воспитания.
Перспективу исследования составляет дальнейший анализ значения и роли социокультурных оснований в эстетическом воспитании педагогов творческих специальностей.
ОСОБЕННОСТИ СТРАХОВАНИЯ В АГРАРНОЙ СФЕРЕ РОССИИ
Authors: Мещанинова Елена  Германовна 
Published: October 2020

Целью исследования является анализ и обоснование особенностей страхования одной из крупных отраслей экономики России — сельского хозяйства, обусловленные природными, климатическими и почвенными условиями.
Методологической основой исследования являются работы отечественных ученых-экономистов, посвященные проблемам страхования, рассматривающие агрострахование как один из инструментов устойчивого развития экономики России. Исследование базируется также на монографическом методе исследования и SWOT-анализе отрасли агрострахования. Несмотря на то, что методологические основы страхования имеют значительную историю, однако недостаточно полно исследованы проблемы внедрения более гибких инструментов агрострахования.
Результаты исследования. Сущность агрострахования в современных условиях заключается в обеспечении защиты агропроизводителей в случае наступления страховых рисков. Однако, проведенный SWOT-анализ отрасли позволяет сделать вывод о низкой мотивации агрострахования и недостаточном доверии со стороны агропроизводителей.
Перспективу исследования составляет дальнейший анализ и изучение возможности применения данных дистанционного зондирования в качестве доказательной базы при наступлении страховых случаев в сельскохозяйственном производстве.
The Interplay of Words and Politics During COVID-19: Contextualizing the Universal Pandemic Vocabulary
Authors: Ali Inayat , Davis-Floyd Robbie 
Published: October 2020

Abstract
In this article, we examine the impacts and effects of the words and terms now related to COVID-19 that have become globally pervasive in social discourse. Illustrating the ongoing interplay between words and politics, we demonstrate how terminologies may shape our interpretations of our experiences and affect the coping strategies we implement. Our arguments draw on Ali’s ethnographic fieldwork on health and illness in Pakistan—primarily on measles and vaccination campaigns in Pakistan’s Sindh province—and his comprehension of local languages and dynamics of power, and Davis-Floyd’s anthropological understandings of the power of language. We argue that using military vocabulary, e.g., “curfew,” “war,” “lock-down,” and the cleverly created “smart lockdown” in Pakistan generates a sense of great “danger” and allows governments to magnify the agency of the virus and to enforce “stringent” measures against its spread. The imported words we discuss herein blur local understandings not only about the virus but also about governmental policies. In contrast, accentuating the importance of local vocabulary, we also argue that local terms, such as “Chilo/â” instead of “Quarantinâ,” would have significantly helped people to make sense of COVID-19 and to take preventive action. We show that becoming conscious about the language used in a pandemic may significantly contribute to efficient ways to contain that pandemic in any country.
Colleagues and Friends: When Collaboration Becomes a Win, Win, Win—The Botanical Research Institute of Texas and Maya Research Program Work Together to Help an Archaeology Project Better Interpret and Protect a Small Portion of Rain Forest
Authors: Bascopé Grace Lloyd , Guderjan Thomas , McClatchey Will 
Published: October 2020

Abstract
Maya Research Program (MRP) has conducted archaeological investigations in Northwestern Belize for twenty plus years. We received a grant from the Botanical Research Institute of Texas to make plant collections in a rainforest remnant, home to the archaeological site of Grey Fox. The team at MRP wished to understand the forest to protect it and the site. In collaboration, we rendered samples of most plant species there, documented ethnobotanical information about the specimens, and gave new insights into ways the collections could be queried to potentially shed light on Ancient Maya plant use and adaptations, subsistence pattern evolution, climate change patterns, and more.