bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neural correlates of temporal updating and reasoning in association with neuropsychiatric disorders
Authors: Ueda Natsuki , Hanakawa Takashi 
Published: December 2019

Abstract
Here we argue how Hoerl & McCormack's dual system proposal may change the current view about the neural correlates underlying temporal information processing. We also consider that the concept of the dual system may help characterize various timing disabilities in neuropsychiatric disorders from the new perspective.
Temporal representation and reasoning in non-human animals
Authors: Kaufmann Angelica , Cahen Arnon 
Published: December 2019

Abstract
Hoerl & McCormack argue that comparative and developmental psychology teaches us that “neither animals nor infants can think and reason about time.” We argue that the authors neglect to take into account pivotal evidence from ethology that suggests that non-human animals do possess a capacity to represent and reason about time, namely, work done on Sumatran orangutans’ long travel calls.
Updating and reasoning: Different processes, different models, different functions
Authors: Kelly Laura , Prabhakar Janani , Khemlani Sangeet 
Published: December 2019

Abstract
Two issues should be addressed to refine and extend the distinction between temporal updating and reasoning advocated by Hoerl & McCormack. First, do the mental representations constructed during updating differ from those used for reasoning? Second, are updating and reasoning the only two processes relevant to temporal thinking? If not, is a dual-systems framework sensible? We address both issues below.
Locating animals with respect to landmarks in space-time
Authors: Gentry Hunter , Buckner Cameron 
Published: December 2019

Abstract
Landmarks play a crucial role in bootstrapping both spatial and temporal cognition. Given the similarity in the underlying demands of representing spatial and temporal relations, we ask here whether animals can be trained to reason about temporal relations by providing them with temporal landmark cues, proposing a line of future research complementary to those suggested by the authors.
“The disadvantages of a defective education”: identity, experiment and persuasion in the natural history of the salmon and parr controversy, c. 1825–1850
Authors: Message Reuben 
Published: December 2019

ArgumentDuring the second quarter of the nineteenth century, an argument raged about the identity of a small freshwater fish: was the parr a distinct species, or merely the young of the salmon? This “Parr Controversy” concerned both fishermen and ichthyologists. A central protagonist in the controversy was a man of ambiguous social and scientific status: a gamekeeper from Scotland named John Shaw. This paper examines Shaw’s heterogeneous practices and the reception of his claims by naturalists as he struggled to find a footing on the “gradient of attributed competence” (Rudwick 1985). The case demonstrates the context-specific nature of expert-lay boundaries and identities and explores a range of material and linguistic resources available for negotiating them. Arguing for a view of Shaw’s trajectory as simultaneously one of being a “practical man” and of becoming a naturalist, the paper explores both the permeability of social hierarchies in knowledge production and their effective role in the regulation of competency.
On commensurability of right-angled Artin groups II: RAAGs defined by paths
Authors: CASALS–RUIZ MONTSERRAT , KAZACHKOV ILYA , ZAKHAROV ALEXANDER 
Published: December 2019

AbstractIn this paper we continue the study of right-angled Artin groups up to commensurability initiated in [CKZ]. We show that RAAGs defined by different paths of length greater than 3 are not commensurable. We also characterise which RAAGs defined by paths are commensurable to RAAGs defined by trees of diameter 4. More precisely, we show that a RAAG defined by a path of lengthn> 4 is commensurable to a RAAG defined by a tree of diameter 4 if and only ifn≡ 2 (mod 4). These results follow from the connection that we establish between the classification of RAAGs up to commensurability and linear integer-programming.
Hitting Two Birds with One Stone: How Russian Countersanctions Intertwined Political and Economic Goals
Authors: Pospieszna Paulina , Skrzypczyńska Joanna , Stępień Beata 
Published: December 2019

ABSTRACTThis article explicates the intertwined economic and political goals behind the imposition of countersanctions through an analysis of their premises and outcomes for Russia’s domestic economy. The evidence supports the argument that retaliation was designed to benefit the Russian domestic food industry, reorient trade relations, and bolster domestic public support for this sector while politically penalizing sanctioning countries. An important contribution of this article is to demonstrate how sanctions imposed on nondemocratic target countries, which play an important role in international affairs, is like a tit-for-tat game, which may have additional effects and also unintended political, economic, and social consequences not yet observed.
Atypical Visual Scan Path Affects Remembering in ADHD
Authors: Mohammadhasani Nasrin , Caprì Tindara , Nucita Andrea , Iannizzotto Giancarlo , Fabio Rosa Angela 
Published: December 2019

AbstractObjective:Several studies agree on the link between attention and eye movements during reading. It has been well established that attention and working memory (WM) interact. A question that could be addressed to better understand these relationships is: to what extent can an attention deficit affect eye movements and, consequently, remembering a word? The main aims of the present study were (1) to compare visual patterns of word stimuli between children with Attention Deficit Hyperactivity Disorder (ADHD) and typically developing (TD) children, during a visual task on word stimuli; (2) to examine the WM accuracy of the word stimuli; and (3) to compare the dynamic of visual scan path in both groups.Method:A total of 49 children with ADHD, age and sex matched with 32 TD children, were recruited. We used eye-tracking technology in which the Word Memory Test was implemented. To highlight the scan path of participants, two measures were used: the ordered direction of reading and the entropy index.Results:ADHD groups showed a poorer WM than TD group. They did not follow a typical scan path across the words compared with TD children, but their visual scanning was discontinuous, uncoordinated, and chaotic. ADHD groups showed an index of entropy among the four categories of saccades higher than TD group.Conclusions:The findings were discussed in light of two directions: the relationship between atypical visual scan path and WM and the training implications related to the necessity of redirecting the dynamic of visual scan path in ADHD to improve WM.
What Difference Does It Make? Gendered Campaigning in the 2016 Irish General Election
Authors: Kusche Isabel 
Published: December 2019

AbstractPossible gender differences in the self-presentation of political candidates have been a recurring research topic for many years. Yet studies that compare large numbers of candidates have mainly used data from the United States. This article uses a unique data set from the run-up to the 2016 general election in Ireland to compare the self-presentation of male and female candidates. The data are based on video statements of almost 90% of the candidates who ran in the election. With its lack of party polarization and recent introduction of a gender quota, Ireland is a particularly interesting case for analyzing possible gender differences in political campaigning. Findings confirm previous research that has found few gender differences in issue priorities but contradict it in other respects, especially regarding differences in stressing political experience and personal background. The results suggest that female candidates saw electoral benefits from conforming to expectations about women as caregivers, but they wished to avoid a stereotype limiting them to this role by also emphasizing their occupational background. Their strong personalization may also indicate an attempt to stress individuality in a context in which the gender quota drew special attention to women as a category.
New Technique for Aerosol Detection in Haze Day Using Side‐Scattering Lidar and Its Inversion Method
Authors: Wang Zhenzhu , Tao Zongming , Liu Dong , Xie Chenbo , Wang Yingjian 
Published: December 2019

AbstractThe new side‐scattering lidar using two charge‐coupled device cameras and one CW laser is developed to measure the near‐ground aerosol profiles in haze day, which is a powerful tool and is most interested for the environmental and meteorological agencies. A new inversion method for the side‐scattering lidar to retrieve the aerosol backscattering coefficient is proposed for the first time, which is based on the aerosol backscattering coefficient measured by itself at the ground as a constrained condition. Numerical simulation is carried out to analyze the convergence of this new method. Case studies indicate that this method is reasonable and feasible. The method is especially suitable for the measurement in the foggy and hazy weathers even during the daytime, and it does not need a simultaneous backscattering lidar as the reference any more.
Application of the Bias Correction and Spatial Downscaling Algorithm on the Temperature Extremes From CMIP5 Multimodel Ensembles in China
Authors: Xu Lianlian , Wang Aihui 
Published: December 2019

AbstractThe Bias Correction and Spatial Downscaling (BCSD) is a trend‐preserving statistical downscaling algorithm, which has been widely used to generate accurate and high‐resolution data set. We employ the BCSD technique to statistically downscale projected daily maximum temperature (DMT) over China from 13 general circulation models in Coupled Model Intercomparison Project Phase 5 (CMIP5) project to supplement the National Aeronautics and Space Administration Earth Exchange Global Daily Downscaled Projections data set under the Representative Concentration Pathway 2.6 (RCP2.6) scenario. We then compare the differences of DMT and four DMT‐related indices (i.e., summer days (SU), annual maximum value of DMT (TXx), intensity, and frequency of heat wave) between before and after downscaling over eight subregions of China. The results indicate that the BCSD method reduces the cool bias of the DMT over the whole China compared with original CMIP5 simulations, especially over the Qinghai‐Tibet plateau. The SU increases after downscaling for both China as a whole and most subregions except for South China. The BCSD also affects the mean value of TXx, intensity, and frequency of heat wave at subregional scales, although it shows little impact on China as a whole. Besides, the BCSD reduces the temporal variability of most indices except for the heat wave frequency. The most striking finding is that the intermodel spreads of DMT, SU, TXx, and heat wave intensity are dramatically reduced after downscaling compared with raw CMIP5 simulations. In summary, the BCSD method shows significant improvements to original CMIP5 climate projections under RCP2.6 scenario.
The odonate phenotypic database, a new open data resource for comparative studies of an old insect order
Authors: Waller John T. , Willink Beatriz , Tschol Maximilian , Svensson Erik I. 
Published: December 2019

AbstractWe present The Odonate Phenotypic Database (OPD): an online data resource of dragonfly and damselfly phenotypes (Insecta: Odonata). Odonata is a relatively small insect order that currently consists of about 6400 species belonging to 32 families. The database consists of multiple morphological, life-history and behavioral traits, and biogeographical information collected from literature sources. We see taxon-specific phenotypic databases from Odonata and other organismal groups as becoming an increasing valuable resource in comparative studies. Our database has phenotypic records for 1011 of all 6400 known odonate species. The database is accessible athttp://www.odonatephenotypicdatabase.org/, and a static version with an information file about the variables in the database is archived at Dryad.
Impact of alternative materials to plasticized PVC infusion tubings on drug sorption and plasticizer release
Authors: Tokhadze N. , Chennell P. , Bernard L. , Lambert C. , Pereira B. , Mailhot-Jensen B. , Sautou V. 
Published: December 2019

AbstractMedical tubings in plasticized polyvinylchloride (PVC) are widely used for the infusion of medications but are known in some cases to cause content-container interactions (drug sorption and plasticizer release). The aim of this study was to assess interactions between drugs and five alternative materials to a reference plasticized PVC intravenous (IV) infusion tubing: three were PVC coextruded with polyethylene (PE), polyurethane (PU) or a thermoplastic elastomer (Styrene-EthyleneButadiene-Styrene (SEBS)) and two were SEBS or thermoplastic olefin (TPO) monolayer tubings. Diazepam and insulin were chosen as respective reference of absorption and adsorption while paracetamol acted as a negative control. The concentration of each drug was quantified with liquid chromatography to evaluate a potential loss after a static contact condition and simulated infusion at 1 mL/h and 10 mL/h dynamic condition by an electric syringe pump. A characterization of each material’s surface was performed by Fourier transform infrared spectroscopy in attenuated total reflection mode (ATR-FTIR) and by measurement of surface zeta potential. Plasticizer release was quantified by gas chromatography coupled with mass spectrometry (GC-MS). For all tubings except PVC/PU, no loss of paracetamol was observed in any condition. Diazepam sorption appeared to be less important with PVC/PE, PVC/SEBS, SEBS and TPO tubings than with PVC, but was more important when using PVC/PU tubings. PVC tubings induced the least loss of insulin amongst all the studied materials. Surface analysis by ATR-FTIR highlighted the presence of a plasticizer (that could be attributed to Tris (2-Ethylhexyl) Trimellitate (TOTM)) in the coextruded SEBS layer of PVC/SEBS, which could have influenced drug sorption, probably as a consequence of a migration from the PVC layer. Coextruded PVC/SEBS and PVC/PE presented the lowest zeta potential of all studied materials with respective values of −39 mV and −36 mV and were related to the highest sorption of insulin while PVC/PU with the highest zeta potential (about −9 mV) presented the highest absorption of diazepam. Coextruded layered materials appeared to have a lower plasticizer release than PVC alone. As a conclusion, PVC/PE and thermoplastic elastomers alone or coextruded with PVC could be interesting alternatives to PVC tubings with regards to sorption phenomena and plasticizer release.
Synthesis and preclinical validation of novel P2Y1 receptor ligands as a potent anti-prostate cancer agent
Authors: Le Hien Thi Thu , Rimpilainen Tatu , Konda Mani Saravanan , Murugesan Akshaya , Yli-Harja Olli , Candeias Nuno R. , Kandhavelu Meenakshisundaram 
Published: December 2019

AbstractPurinergic receptor is a potential drug target for neuropathic pain, Alzheimer disease, and prostate cancer. Focusing on the structure-based ligand discovery, docking analysis on the crystal structure of P2Y1 receptor (P2Y1R) with 923 derivatives of 1-indolinoalkyl 2-phenolic compound is performed to understand the molecular insights of the receptor. The structural model identified the top novel ligands, 426 (compound 1) and 636 (compound 2) having highest binding affinity with the docking score of −7.38 and −6.92. We have reported the interaction efficacy and the dynamics of P2Y1R protein with the ligands. The best hits synthesized were experimentally optimized as a potent P2Y1 agonists. These ligands exhibits anti-proliferative effect against the PC-3 and DU-145 cells (IC50 = 15 µM – 33 µM) with significant increase in the calcium level in dose- and time-dependent manner. Moreover, the activation of P2Y1R induced the apoptosis via Capase3/7 and ROS signaling pathway. Thus it is evidenced that the newly synthesized ligands, as a P2Y1R agonists could potentially act as a therapeutic drug for treating prostate cancer.
Dynamic range expansion leads to establishment of a new, genetically distinct wolf population in Central Europe
Authors: Szewczyk Maciej , Nowak Sabina , Niedźwiecka Natalia , Hulva Pavel , Špinkytė-Bačkaitienė Renata , Demjanovičová Klára , Bolfíková Barbora Černá , Antal Vladimír , Fenchuk Viktar , Figura Michał , Tomczak Patrycja , Stachyra Przemysław , Stępniak Kinga M. , Zwijacz-Kozica Tomasz , Mysłajek Robert W. 
Published: December 2019

AbstractLocal extinction and recolonization events can shape genetic structure of subdivided animal populations. The gray wolf (Canis lupus) was extirpated from most of Europe, but recently recolonized big part of its historical range. An exceptionally dynamic expansion of wolf population is observed in the western part of the Great European Plain. Nonetheless, genetic consequences of this process have not yet been fully understood. We aimed to assess genetic diversity of this recently established wolf population in Western Poland (WPL), determine its origin and provide novel data regarding the population genetic structure of the grey wolf in Central Europe. We utilized both spatially explicit and non-explicit Bayesian clustering approaches, as well as a model-independent, multivariate method DAPC, to infer genetic structure in large dataset (881 identified individuals) of wolf microsatellite genotypes. To put the patterns observed in studied population into a broader biogeographic context we also analyzed a mtDNA control region fragment widely used in previous studies. In comparison to a source population, we found slightly reduced allelic richness and heterozygosity in the newly recolonized areas west of the Vistula river. We discovered relatively strong west-east structuring in lowland wolves, probably reflecting founder-flush and allele surfing during range expansion, resulting in clear distinction of WPL, eastern lowland and Carpathian genetic groups. Interestingly, wolves from recently recolonized mountainous areas (Sudetes Mts, SW Poland) clustered together with lowland, but not Carpathian wolf populations. We also identified an area in Central Poland that seems to be a melting pot of western, lowland eastern and Carpathian wolves. We conclude that the process of dynamic recolonization of Central European lowlands lead to the formation of a new, genetically distinct wolf population. Together with the settlement and establishment of packs in mountains by lowland wolves and vice versa, it suggests that demographic dynamics and possibly anthropogenic barriers rather than ecological factors (e.g. natal habitat-biased dispersal patterns) shape the current wolf genetic structure in Central Europe.
Induction of PrMADS10 on the lower side of bent pine tree stems: potential role in modifying plant cell wall properties and wood anatomy
Authors: Cruz Nicolás , Méndez Tamara , Ramos Patricio , Urbina Daniela , Vega Andrea , Gutiérrez Rodrigo A. , Moya-León María A. , Herrera Raúl 
Published: December 2019

AbstractThe molecular mechanisms underlying inclination responses in trees are unclear. In this study, we identified a MADS-box transcription factor differentially expressed early after inclination in the stems of Pinus radiata D. Don. PrMADS10 has a CDS of 582 bp and encodes a group II MADS-box transcription factor. We measured highest accumulation of this transcript on the lower side of inclined pine stems. In an effort to identify putative targets, we stably transformed Arabidopsis thaliana with a 35S::PrMADS10 construct. Transcriptome analysis revealed 1,219 genes differentially-expressed, with 690 and 529 genes up- and down-regulated respectively, when comparing the transgenic and wild-type. Differentially-expressed genes belong to different biological processes, but were enriched in cell wall remodeling and phenylpropanoid metabolic functions. Interestingly, lignin content was 30% higher in transgenic as compared to wild-type plants consistent with observed changes in gene expression. Differentially expressed transcription factors and phenylpropanoid genes were analyzed using STRING. Several MYB and NAC transcription factors showed interactions with genes of the phenylpropanoid pathway. Together, these results implicate PrMADS10 as a regulatory factor, triggering the expression of other transcription factors and genes involved in the synthesis of lignin.
Effects of disease, antibiotic treatment and recovery trajectory on the microbiome of farmed seabass (Dicentrarchus labrax)
Authors: Rosado Daniela , Xavier Raquel , Severino Ricardo , Tavares Fernando , Cable Jo , Pérez-Losada Marcos 
Published: December 2019

AbstractThe mucosal surfaces of fish harbour microbial communities that can act as the first-line of defense against pathogens. Infectious diseases are one of the main constraints to aquaculture growth leading to huge economic losses. Despite their negative impacts on microbial diversity and overall fish health, antibiotics are still the method of choice to treat many such diseases. Here, we use 16 rRNA V4 metataxonomics to study over a 6 week period the dynamics of the gill and skin microbiomes of farmed seabass before, during and after a natural disease outbreak and subsequent antibiotic treatment with oxytetracycline. Photobacterium damselae was identified as the most probable causative agent of disease. Both infection and antibiotic treatment caused significant, although asymmetrical, changes in the microbiome composition of the gills and skin. The most dramatic changes in microbial taxonomic abundance occurred between healthy and diseased fish. Disease led to a decrease in the bacterial core diversity in the skin, whereas in the gills there was both an increase and a shift in core diversity. Oxytetracycline caused a decrease in core diversity in the gill and an increase in the skin. Severe loss of core diversity in fish mucosae demonstrates the disruptive impact of disease and antibiotic treatment on the microbial communities of healthy fish.
Nutrient patterns and the skeletal muscle mass index among Polish women: a cross-sectional study
Authors: Danielewicz Anna , Morze Jakub , Obara-Gołębiowska Małgorzata , Przybyłowicz Mariusz , Przybyłowicz Katarzyna E. 
Published: December 2019

AbstractAgeing involves significant changes in skeletal muscle mass and its functioning. This study aimed to identify the major nutrient patterns (NPs) present in a sample of adult Polish women and evaluate their associations with the skeletal muscle mass index (SMI). A cross-sectional study initially recruited 527 women, and a final analysis was carried out on 275 women aged 32–60 years. Nutrient intake was assessed using fourteen repetitions of 24-hour dietary recall. NPs were derived using principal component analysis. Associations between adherence to NPs and the SMI were evaluated using linear regression models. Three NPs were identified: ‘Animal Protein-Vitamins’, ‘Fibre-Plant Protein-Minerals’ and ‘Fats’. In the adjusted model, the upper tertile compared to the bottom tertile of the ‘Animal Protein-Vitamins’ NP was related to a higher SMI (β = 0.123 95% CI: 0.019; 0.227;Pfor 1-SD increase of NP score = 0.009). No associations between the SMI and the ‘Fibre-Plant Protein-Minerals’ and ‘Fats’ NPs were observed. Our results indicate that high adherence to animal product-rich patterns might be related to higher muscle mass in adult women. Research on the influence of dietary and nutrient patterns on the quality of muscle tissue may contribute to the setting of guidelines for nutritional protection of skeletal muscle with ageing and, consequently, dietary recommendations that would improve the quality of women’s lives at the later stage of life.