bluuebunny/crossref_metadata_2025_split huggingface dataset:
Des familles conso-motrices ? Ethnographie des mobilités alimentaires dans les pratiques d’approvisionnement en France
Authors: Vicart Marion , Wathelet Olivier 
Published: October 2019

Dans cet article nous discutons de la part des mobilités individuelles dans la constitution des pratiques d’approvisionnement alimentaire familiales. L’analyse s’appuie sur une enquête ethnographique de 18 mois, auprès de 24 familles françaises. Elle montre en quoi les pratiques de consommation alimentaire sont structurées par des lieux de vie et des mobilités quotidiennes, sous la forme de chaînage censé réduire le volume des déplacements. Toutefois, on observe comment, en retour, les mobilités des personnes sont également influencées par leurs décisions et arbitrages alimentaires. Des « parcours d’approvisionnement » sont mis en place en fonction de leurs choix d’approvisionnement et des événements biographiques, marquant ainsi une forte distribution dans leurs pratiques entre courses plaisirs et courses contraintes. Ensuite, au-delà de leur valeur symbolique, ces deux modalités d’approvisionnement recouvrent des expériences spécifiques d’inscription dans l’espace. En nous appuyant notamment sur le cas du « drive » (distribution via un point de livraison d’achats commandés préalablement sur internet), on propose ainsi de montrer l’interdépendance entre déplacements alimentaires et déplacements humains au sein de pratiques « conso-motrices ». Ainsi, contre l’idée d’un approvisionnement stratégiquement adossé aux mobilités quotidiennes, on voit comment la recherche d’un “bien consommer” module ces déplacements et construit une expérience spécifique du choix alimentaire.
L’abattoir dans le cinéma de fiction : un site coupé en quatre
Authors: Chenille Vincent 
Published: October 2019

Basé sur un corpus de 35 films internationaux de fiction, l’article étudie la représentation des abattoirs de 1950 à nos jours (bien que des références en la matière existent dès les années 30). Sans être exhaustif, le corpus est représentatif des filmographies nationales et des décennies remarquables : le cinéma américain, mais aussi français et hongkongais sont particulièrement étudiés, de même que les années soixante-dix et deux mille. Le cinéma a coupé l’abattoir en quatre : la chambre froide, la tuerie, la découpe et le transport. Si la tuerie et la découpe n’apparaissent qu’avec les années soixante-dix, les années quatre-vingt-dix n’ont montré que la chambre froide et le transport, alors que les années deux-mille se concentreront sur la découpe. Si l’Asie et les Etats-Unis ont montré la tuerie, l’Europe a été plus réticente à montrer cette partie.
L'abattage en Inde
Authors: Bruckert Michaël 
Published: October 2019

Cet article interroge les reconfigurations spatiales et organisationnelles de l’abattage dans le monde indien. En s’appuyant sur des recherches menées entre 2011 et 2014 dans l’État du Tamil Nadu, il met en lumière les processus qui sous-tendent ces reconfigurations. En Inde, les configurations spatiales de l’organisation du travail dans les abattoirs municipaux diffèrent de celles à l’œuvre dans les abattoirs industriels. Dans l’abattoir municipal de Chennai, la saignée, la dépouille, l’éviscération et la découpe se font dans un même lieu. Cependant, une frontière nette et hermétique sépare la section des caprinés de celle des bovinés : cette frontière peut être comprise comme l’inscription dans l’espace de l’abattoir d’une hiérarchie de l’impureté qui affecte les individus et les viandes. Plus généralement, les lieux d’abattage sont des arènes de mobilisation politique où prennent place des conflits opposant les bouchers traditionnels, les décideurs politiques, les groupes agro-industriels, les experts scientifiques, les militants écologistes ou animalistes et les partisans du nationalisme hindou. Cet article montre que les différentes logiques de localisation et configurations techno-spatiales des lieux d’abattage renvoient à différents régimes de régulation de l’impureté organique, morale ou religieuse à laquelle les groupes dominants associent la viande en Inde.
La mise en application d’un règlement de protection animale au regard de la structuration des abattoirs français
Authors: Jourdan Félix , Hochereau François 
Published: October 2019

Le processus d’industrialisation a transformé les abattoirs jusqu’à aboutir à deux modèles relativement distincts : des grands sites privés qui ne cessent d’accroître leur volume d’abattage et des petits établissements à faible production qui assurent un service de prestation dans une localité donnée. La mise en œuvre du règlement de protection animale n°1099/2009 pourrait accentuer la fragilité socioéconomique des petits abattoirs en raison des travaux de rénovation qu’elle exige. Ce faisant, elle renforcerait la concentration industrielle des abattages et, par extension, la sur-rationalisation des grands abattoirs. Or, la protection animale nécessite de transcender les rigidités structurelles et de replacer la relation de travail homme-animal au centre des organisations. En la matière, les petits abattoirs pourraient bénéficier d’un avantage sur les plus grands à condition d’être soutenus, en particulier sur le plan financier.
Impact of the Paris system for reporting urine cytopathology on predictive values of the equivocal diagnostic categories and interobserver agreement
Authors: Bakkar Rania , Mirocha James , Fan Xuemo , Frishberg David P. , Peralta-Venturina Mariza de , Zhai Jing , Bose Shikha 
Published: October 2019

Background:
The Paris System (TPS) acknowledges the need for more standardized terminology for reporting urine cytopathology results and minimizing the use of equivocal terms. We apply TPS diagnostic terminologies to assess interobserver agreement, compare TPS with the traditional method (TM) of reporting urine cytopathology, and evaluate the rate and positive predictive value (PPV) of each TPS diagnostic category. A survey is conducted at the end of the study.

Materials and Methods:
One hundred urine samples were reviewed independently by six cytopathologists. The diagnosis was rendered according to TPS categories: negative for high-grade urothelial carcinoma (NHGUC), atypical urothelial cells (AUC), low-grade urothelial neoplasm (LGUN), suspicious for high-grade urothelial carcinoma (SHGUC), and high-grade urothelial carcinoma (HGUC). The agreement was assessed using kappa. Disagreements were classified as high and low impacts. Statistical analysis was performed.

Results:
Perfect consensus agreement was 31%, with an overall kappa of 0.362. Kappa by diagnostic category was 0.483, 0.178, 0.258, and 0.520 for NHGUC, AUC, SHGUC, and HGUC, respectively. Both TM and TPS showed 100% specificity and PPV. TPS showed 43% sensitivity (38% by TM) and 70% accuracy (66% by TM). Disagreements with high clinical impact were 27%. Of the 100 cases, 52 were concurrent biopsy-proven HGUC. The detection rate of biopsy-proven HGUC was 43% by TPS (57% by TM). The rate of NHGUC was 54% by TPS versus 26% by TM. AUC rate was 23% by TPS (44% by TM). The PPV of the AUC category by TPS was 61% versus 43% by TM. The survey showed 33% overall satisfaction.

Conclusions:
TPS shows adequate precision for NHGUC and HGUC, with low interobserver agreement for other categories. TPS significantly increased the clinical significance of AUC category. Refinement and widespread application of TPS diagnostic criteria may further improve interobserver agreement and the detection rate of HGUC.
Robotic surgery in paediatric patients
Authors: Sinha Arvind , Pathak Manish , Vig Ayushi , Saxena Rahul 
Published: October 2019

Introduction:
The popularity of robot-assisted surgeries has accelerated since its advent in 1990s. Recently, we procured da Vinci surgical system in our institution; and here, we present our initial experience of robot-assisted surgeries at our hospital. We also discuss the stepwise approach for successful implementation of the robotic surgical programme at our institute. Moreover, the importance of efficient use of this advanced but expensive technology has been highlighted.

Materials and Methods:
Retrospective analysis of the medical record of all the paediatric patients between the age ranges of 1–18 years who had undergone robotic-assisted laparoscopic surgery during April 2019–April 2019 was done. Medical record was reviewed for descriptive data, clinical presentation, investigations, operative details and follow-up. Statistical data were also obtained from medical superintendent office.

Results:
During April 2018–April 2019, total of 111 cases were operated across six specialities. Approximately 73% of cases (81/111) belonged to adult urology and gynaecology speciality. Less than 5% (5/111) of patients were in paediatric age group. The department of paediatric surgery performed one pyeloplasty, 3 ureteric reimplantation and 1 bladder diverticulum excision with robot assistance. The operative duration of the cases was comparable to the standard laparoscopic techniques. All patients are asymptomatic on follow-up visits.

Conclusion:
The robotic surgery is feasible in paediatric population and has favourable post-operative outcomes. Detailed planning and stepwise approach is key to the establishment of new robotic surgery programme in any institute.
Advances in soft-tissue sarcoma – There are no mistakes, only lessons to learn!
Authors: Rastogi Sameer , Manasa Parisa , Aggarwal Aditi , Kalra Kaushal 
Published: October 2019

Abstract
Background: In this decade the treatment of advanced sarcoma has seen many highs and lows in terms of successful trials and failed trials. This is possible due to great collaborations, newer therapies and histology focused trials. Methods: In ASCO 2019 many sarcoma trials were presented and we chose 3 challenging clinical trials that widen our perspective on soft tissue sarcoma. We have critically analyzed the data and have discussed the implications of these trials on current practice. First trial was ANNOUNCE trial which was done to confirm the efficacy of olaratumab after its dramatic success in advanced soft tissue sarcoma in a phase 2 trial. Another trial STRASS trial, which was unique because of being first successfully conducted randomized trial addressing preoperative radiotherapy in retroperitoneal soft tissue sarcoma. Third trial was phase 2 trial SARC 028 trial exploring the role of immunotherapy in pleomorphic undifferentiated sarcoma and liposarcoma subgroup. Result: ANNOUNCE trial failed to show OS benefit in olaratumab/doxorubicin arm as compared to doxorubicin/placebo arm . Based upon this FDA has revoked the approval of olaratumab leading to nihilism and disappointment amongst oncologists. In STRASS trial failed to meet the primary end point though there was a benefit in the liposarcoma subgroup in terms of abdominal recurrence free survival. There are several reasons that this trial might have failed. First, RPSs are not homogeneous population. RPSs might behave very differently as per the histopathology ranging from well differentiated LPS to leiomyosarcoma. Since the event rate in well-differentiated liposarcoma might happen late, the median follow-up of 43 months might not be sufficient. In SARC trial ORR in pleomorphic undifferentiated sarcoma (PUS) cohort was 9/40 (22.5%), while response rates in liposarcoma cohort were 4/39 (10.2%). There was poor correlation between the response and the tumor cells’ PD-L1 positivity. Simultaneously, we must not take for granted the role of pembrolizumab in PUS as the previous study (PEMBROSARC) had also showed dismal outcomes with immunotherapy. Conclusion: In this paper we discuss the intricacies of these trials and how they affect the rapidly changing landscape in advanced soft tissue sarcoma.
Clinico-epidemiological features and response in childhood acute lymphoblastic leukemia at regional cancer center of Northeast India
Authors: Saikia Bhargab Jyoti , Roy Partha Sarathi , Kumar Gaurav , Mishra Rakesh Kumar , Sarma Anupam 
Published: October 2019

Abstract
Introduction: Acute lymphoblastic leukemia (ALL) comprises 19.3% of all childhood cancers in Northeast India. Methods: We analyzed clinicoepidemiological features and early response to the treatment of all the cases of childhood ALL (age <15 years) diagnosed and treated at Dr. B Borooah Cancer Institute over 1 year. Results: Of 52 eligible cases, 69% were male (male:female ratio of 2.2:1) and the mean age was 7.1 years. Thirty-three children (63%) had baseline white blood cell count ≥20 × 109/L. Precursor B-cell was most the common subtype seen in 61% of children. Seven cases (14%) had high-risk (HR) cytogenetics, with t (9,22) being the most common one. Male sex and HR cytogenetics were significantly associated with poor early responses. Conclusion: ALL is a common childhood malignancy with high cure rates. However, poor socioeconomic status and the presence of higher proportions of disease-related factors lead to poor outcome in this part of the country.
Droplet digital polymerase chain reaction offers an improvisation over conventional immunohistochemistry and fluorescent in situ hybridization for ascertaining Her2 status of breast cancer
Authors: Suryavanshi Moushumi , Jaipuria Jiten , Mehta Anurag , Kumar Dushyant , Panigrahi Manoj Kumar , Verma Haristuti , Saifi Mumtaz , Sharma Sanjeev , Tandon Simran , Doval Dinesh Chandra , Das Bhudev C. 
Published: October 2019

Abstract
Background: Droplet digital polymerase chain reaction (DDPCR) is a recent modality for detecting Her2 expression which is quantitative, cheaper, easier to standardize, and free from interobserver variation. Purpose: The purpose of this study is to incorporate DDPCR in the current diagnostic paradigm with clinical benefit. Materials and Methods: Fifty-four consecutive patients were tested by immunohistochemistry (IHC), fluorescent in situ hybridization (FISH), and DDPCR. With FISH result as gold standard, receiver operating characteristic curves for DDPCR ratio were analyzed to label Her2-negative, equivocal, and positive cases as DDPCR score 1, 2, and 3, respectively. Proportion of patients labeled unequivocally as Her2 positive or negative was defined to have “clinically benefitted” from the test. Drawing parallel to inter-relationships between DDPCR, IHC, and FISH in the test cohort, four diagnostic pathways were defined – (1) initial IHC followed by FISH, (2) initial DDPCR followed by FISH, (3) initial IHC followed by DDPCR followed by FISH, and (4) initial DDPCR followed by IHC followed by FISH. Results: Clinical benefit of DDPCR as an initial test in the test cohort was 57%, while it was 65% if used as a second-line test among those with an initial inconclusive IHC result. Sensitivity analysis in the simulation cohort revealed that if DDPCR cost was ≤0.6 times the cost of IHC, then a three-step pathway with DDPCR upfront would near certainly prove most cost beneficial. If DDPCR cost was >0.6 but ≤2 times the cost of IHC, then a three-step pathway with DDPCR as second-line test had a higher probability to prove most cost beneficial. If DDPCR cost was >2 times the cost of IHC, then conventional pathway had a higher probability to prove most cost-effective. Conclusion: Incorporating DDPCR in the current clinical diagnostic paradigm has the potential to improve its cost-effectiveness and benefit.
Usefulness of narrow-band imaging in transurethral resection of bladder tumor: Early experience from a tertiary center in India
Authors: Malik Kanuj , Raja Anand , Mahalingam Sivakumar , Ravishankar L.S 
Published: October 2019

Abstract
Background: The current standard for diagnosis and treatment of urinary bladder cancer is transurethral resection of bladder tumor (TURBT) using white light guidance. Narrow band imaging (NBI) has emerged as a promising method for identifying additional bladder lesions. Various studies have been published to evaluate its sensitivity in identifying new lesions and its impact on decreasing recurrences. In this study, we evaluated our early experience using NBI in TURBTs. Aims and Objective: The aim of the study is to determine the accuracy of NBI in identifying additional malignant lesions during TURBT. Materials and Methods: We retrospectively collected data for all patients who underwent either TURBT or repeat TURBT with white light and NBI from November 2016 to July 2017 at Cancer Institute (WIA). The number of additional lesions identified using NBI was evaluated along with its correlation with the final histopathology. Results: Forty patients were analysed of which 20 underwent TURBT and 20 underwent repeat TURBT. Of these, 36 patients had complete resection of tumour. Additional lesions were detected in 6 patients (14%) by NBI of which 2 (33%) were malignant histology. The additional lesions detected were carcinoma in situ and no patient was upstaged. Conclusion: The inclusion of NBI to conventional white light TURBT increases the sensitivity for identifying additional lesions. The limitation of NBI is high false positivity and its availability. Long term follow up studies with larger subset of patients are required to evaluate its role in decreasing recurrences and justification in routine clinical practice.
Predictive biomarkers in nonsmall cell carcinoma and their clinico-pathological association
Authors: Mehta Anurag , Sriramanakoppa Nayana N. , Agarwal Poojan , Viswakarma Gayatri , Vasudevan Smreti , Panigrahi Manoj , Kumar Dushyant , Saifi Mumtaz , Chowdhary Irfan , Doval D.C , Suryavanshi Moushumi 
Published: October 2019

Abstract
Background: Lung cancer is the leading cause of cancer-related mortality worldwide. Genome-directed therapy is less toxic, prolongs survival and provides a better quality of life. Predictive biomarker testing, therefore, has become a standard of care in advanced lung cancers. The objective of this study was to relate clinical and pathological features, including response to targeted therapy (TT) and progression-free survival (PFS) with positive driver mutation. Materials and Methods: Archival data of nonsmall cell carcinoma patients with Stage IV disease were retrieved. Those who tested positive for one of the four biomarkers (epidermal growth factor receptor [EGFR], anaplastic lymphoma kinase [ALK], MET, and ROS) were included. Patient demographics and clinical features were reviewed. Tumor histomorphology was correlated with oncological drivers. Treatment response, PFS, and overall survival were studied in three subcohorts of patients who received computed tomography (CT), CT followed by TT and those who received TT in the first line. Results: A total of 900 patients underwent biomarker evaluation of which 288 tested positive. Frequency of the four biomarkers observed was 26.6% (229/860), 6.6% (51/775), 6.6% (5/75), and 5.1% (3/59) for EGFR, ALK, MET, and ROS-1, respectively. The median PFS for EGFR-mutated cohort was 12 months, whereas it was 21 months for ALK protein overexpressing cases. Patients treated with first-line tyrosine kinase inhibitors performed better compared to those who were switched from chemotherapy to TT or those who received chemotherapy alone (P < 0.05). Conclusion: Biomarker testing has improved patient outcome. Genome-directed therapy accords best PFS with an advantage of nearly 10 months over cytotoxic therapy.
Ensemble models from machine learning: an example of wave runup and coastal dune erosion
Authors: Beuzen Tomas , Goldstein Evan B. , Splinter Kristen D. 
Published: October 2019

Abstract. After decades of study and significant data collection of time-varying swash on sandy beaches, there is no single deterministic prediction scheme for wave runup that eliminates prediction error – even bespoke, locally tuned predictors present scatter when compared to observations. Scatter in runup prediction is meaningful and can be used to create probabilistic predictions of runup for a given wave climate and beach slope. This contribution demonstrates this using a data-driven Gaussian process predictor; a probabilistic machine-learning technique. The runup predictor is developed using 1 year of hourly wave runup data (8328 observations) collected by a fixed lidar at Narrabeen Beach, Sydney, Australia. The Gaussian process predictor accurately predicts hourly wave runup elevation when tested on unseen data with a root-mean-squared error of 0.18 m and bias of 0.02 m. The uncertainty estimates output from the probabilistic GP predictor are then used practically in a deterministic numerical model of coastal dune erosion, which relies on a parameterization of wave runup, to generate ensemble predictions. When applied to a dataset of dune erosion caused by a storm event that impacted Narrabeen Beach in 2011, the ensemble approach reproduced ∼85 % of the observed variability in dune erosion along the 3.5 km beach and provided clear uncertainty estimates around these predictions. This work demonstrates how data-driven methods can be used with traditional deterministic models to develop ensemble predictions that provide more information and greater forecasting skill when compared to a single model using a deterministic parameterization – an idea that could be applied more generally to other numerical models of geomorphic systems.
The effect of Diesel-Methanol Blends with Volumetric Proportions on The Performance and Emissions of A Diesel Engine
Authors: BERBER ADNAN 
Published: October 2019

In this work, the methanol is added to the diesel fuel in the volumetric proportions of 5%-%10-%15 to diminish negative environmental impacts of diesel engines. The diesel-methanol blends in the various proportions are tested in a single-cylinder direct-injection diesel engine. According to the test results, the addition of methanol to the diesel fuel causes a maximum decrease of 13.07 % in the engine torque, and a maximum decrease of 12.54 % in the specific fuel consumption. On the other hand, the exhaust emission results show that the values of CO and CO2 decrease 38.4 % and 5.04%. However, the increase of 3.66% in the exhaust gas temperature causes the increase of 17.1% in the NOx emission. Also, a significant decrease of 39.37% in the smoke opacity is observed compared to that of the diesel fuel. Although the addition of methanol to diesel fuel causes a slightly decrease in the engine performance, the diesel-methanol blends have a reasonable and considerable positive effect on environmental concerns of diesel engines.
Performance and emission characteristics of preheating corn oil methyl ester in CI Engine
Authors: Varudharajan Gopinath 
Published: October 2019

In the present work on unheated Corn oil methyl ester and Preheated Corn oil methyl ester is used to prepare different concentration blends with diesel, B20, B40 and B60 were used as alternative fuels in a compression ignition engine. The properties like calorific value, flash point, fire point and viscosity of these oils were determined. The viscosity of corn oils has been reduced through transterification process. The waste heat energy from the exhaust gas was reused to preheat the corn oil around 80°C by adjusting the flow rate of exhaust gas. The performance and emission characteristics of a single cylinder, direct injection diesel engine were determined using unheated corn oil, Preheated Corn oil and diesel. Brake thermal efficiency of preheated B20 was more than other blends and unheated fuels but equal to diesel fuel. Brake specific fuel consumption, CO2 and HC of preheated B20 were less than unheated fuels and diesel. However, the NOx emission of preheated B20 was little higher than unheated fuels and diesel due to high combustion temperature. By considering the result of all the factors, preheated B20 blend was found to be a suitable alternative for diesel fuel.