bluuebunny/crossref_metadata_2025_split huggingface dataset:
International Practice Patterns of Antibiotic Therapy and Laboratory Testing in Bronchiolitis
Authors: Zipursky Amy , Kuppermann Nathan , Finkelstein Yaron , Zemek Roger , Plint Amy C. , Babl Franz E. , Dalziel Stuart R. , Freedman Stephen B. , Steele Dale W. , Fernandes Ricardo M. , Florin Todd A. , Stephens Derek , Kharbanda Anupam , Roland Damian , Lyttle Mark D. , Johnson David W. , Schnadower David , Macias Charles G. , Benito Javier , Schuh Suzanne ,   FOR THE PEDIATRIC EMERGENCY RESEARCH NETWORKS (PERN)
Published: July 2020

BACKGROUND AND OBJECTIVES:
International patterns of antibiotic use and laboratory testing in bronchiolitis in emergency departments are unknown. Our objective is to evaluate variation in the use of antibiotics and nonindicated tests in infants with bronchiolitis in 38 emergency departments in Pediatric Emergency Research Networks in Canada, the United States, Australia and New Zealand, the United Kingdom and Ireland, and Spain and Portugal. We hypothesized there would be significant variation, adjusted for patient characteristics.

METHODS:
We analyzed a retrospective cohort study of previously healthy infants aged 2 to 12 months with bronchiolitis. Variables examined included network, poor feeding, dehydration, nasal flaring, chest retractions, apnea, saturation, respiratory rate, fever, and suspected bacterial infection. Outcomes included systemic antibiotic administration and urine, blood, or viral testing or chest radiography (CXR).

RESULTS:
In total, 180 of 2359 (7.6%) infants received antibiotics, ranging from 3.5% in the United Kingdom and Ireland to 11.1% in the United States. CXR (adjusted odds ratio [aOR] 2.3; 95% confidence interval 1.6–3.2), apnea (aOR 2.2; 1.1–3.5), and fever (aOR 2.4; 1.7–3.4) were associated with antibiotic use, which did not vary across networks (P = .15). In total, 768 of 2359 infants (32.6%) had ≥1 nonindicated test, ranging from 12.7% in the United Kingdom and Ireland to 50% in Spain and Portugal. Compared to the United Kingdom and Ireland, the aOR (confidence interval) results for testing were Canada 5.75 (2.24–14.76), United States 4.14 (1.70–10.10), Australia and New Zealand 2.25 (0.86–5.74), and Spain and Portugal 3.96 (0.96–16.36). Testing varied across networks (P &lt; .0001) and was associated with suspected bacterial infections (aOR 2.12; 1.30–2.39) and most respiratory distress parameters. Viral testing (591 of 768 [77%]) and CXR (507 of 768 [66%]) were obtained most frequently.

CONCLUSIONS:
The rate of antibiotic use in bronchiolitis was low across networks and was associated with CXR, fever, and apnea. Nonindicated testing was common outside of the United Kingdom and Ireland and varied across networks irrespective of patient characteristics.
Les romanciers du rugby dans la France des années 1920
Authors: Bauer Thomas , Vincent Joris 
Published: July 2020

Faut-il voir dans les années 1920 une période faste pour la littérature à thème rugbystique ? En effet, qu’ils soient auteurs reconnus ou simples journalistes sportifs, plusieurs écrivains se sont emparés des opportunités éditoriales de l’époque pour raconter des histoires de rugby. Au-delà de leur caractère anecdotique ou promotionnel, ces dernières constituent une véritable source d’informations pour étudier la démocratisation d’un sport qui, à Paris comme dans les grandes villes de province, encourageait la noblesse du jeu et l’élégance de ses champions par-delà les rivalités et autres soupçons d’amateurisme marron. Toutefois, la littérature étant aussi un moyen de dire et d’interroger l’expérience du premier conflit mondial, certains romanciers ont rapproché métaphoriquement le rugby et la guerre pour mieux réinterroger, a posteriori, le sens du « Grand Match ». L’analyse de ces pages littéraires souhaite apporter un éclairage original pour appréhender, autrement, l’histoire du rugby français au cours des Années folles.
Die Vertreter der Rugbyliteratur im Frankreich der 1920er Jahre
Authors: Bauer Thomas , Vincent Joris 
Published: July 2020

Sind die 1920er Jahre als eine Blütezeit der Rugby-Themenliteratur zu betrachten? Ob anerkannte Schriftsteller oder einfache Sportjournalisten, mehrere Autoren nutzten tatsächlich die Veröffentlichungsmöglichkeiten der damaligen Zeit, um Geschichten über Rugby zu erzählen. Abgesehen von ihrem anekdotischen oder werbewirksamen Charakter stellen diese Geschichten eine ausgezeichnete Informationsquelle dar, um die Demokratisierung eines Sports zu untersuchen, der sowohl in Paris als auch in den anderen französischen Großstädten die Erhabenheit des Spiels und die Eleganz seiner Talente förderte, jenseits von Rivalitäten und Verdachtsmomenten zur unerlaubten Bezahlung von Amateurspielern. Gleichwohl dient die Literatur der damaligen Zeit auch dazu, die Erfahrungen des Ersten Weltkriegs zu erzählen und zu reflektieren, was einige Schriftsteller dazu veranlasst hat, den Sport auf metaphorischer Ebene dem Krieg anzunähern, um die Bedeutung des „Großen Matches“ a posteriori neu zu hinterfragen. Die vorliegende Literaturanalyse soll einen neuen Einblick in die Geschichte des französischen Rugbys während der Goldenen Zwanziger gewähren.
Aus dem Französischem von Alfred Jürgens.
Sur la signification sociale et culturelle d'un sport aussi latin
Authors: Conord Fabien , Lehnert Joris 
Published: July 2020

Cette introduction vise à donner un aperçu général sur le rugby, son évolution (voire révolution) depuis une vingtaine d’année et ses enjeux actuels, car ce sport est un objet peu connu de la recherche en langue allemande. En contrepoint de l’idée que le rugby serait un sport à tradition presqu’exclusivement britannique, nous nous y intéressons donc avec un point de vue centré sur les pays de langues latines. En partant de l’exemple français et de sa culture rugbystique très forte, nous nous interrogeons sur une éventuelle culture ou identité propre au rugby latin. En effet, le rugby est également plus ou moins ancré dans un certain nombre de ces pays et, historiquement, la plus grande partie des nations qui ont pu représenter une concurrence (plus ou moins forte) aux nations britanniques ou du Pacifique ont toutes le même point commun : d’être justement de culture latine.
El rugby español de ayer y de hoy
Authors: Gounot André , Laorden María Teresa 
Published: July 2020

Carlos Bernardos Vallejo se inició en el mundo del rugby como jugador a los 18 años en el equipo de la Escuela de Ingenieros de Montes de Madrid, tanto en liga universitaria como en la liga madrileña de segunda regional. Más tarde recaló en el CEU entrenado por André Medan durante varias temporadas y, cuando Medan volvió a Francia, tomó el papel de entrenador del club. Posteriormente, al fusionarse su equipo con el TECA, fundaron el Alcobendas R.C. En el año 1988 dejó de ser jugador definitivamente para dirigir al equipo como entrenador y en 1994 comenzó a trabajar con la Federación Española de Rugby en diversos puestos: como Director Técnico hasta 2003, al mismo tiempo que fue Coordinador de la Preparación física y Preparador Físico de las Selecciones Nacionales Absoluta, Femenina, Junior, Senior masculina de rugby a 7 y Senior femenina de rugby a 7 entre los año 1998 y 2009 . También ha sido Asesor Técnico de Alta Competición de la Federación Española de Rugby de 2013 a 2010 y Director de la Escuela Nacional de Entrenadores de la Federación Española de Rugby durante 5 años. Hace 4 temporadas volvió a los campos como entrenador, para trabajar con el equipo femenino del Olímpico de Pozuelo durante tres temporadas, quedando las dos últimas campeonas de España, y una cuarta temporada con el equipo masculino.
Teknik Relaksasi Progresive Untuk Menurunkan Tingkat Kecemasan Siswa Menghadapi Ujian Nasional Berbasis Komputer
Authors: Nurnaningsih Nurnaningsih 
Published: July 2020

This study aims to apply Relaxation Techniques to reduce the level of anxiety of high school students when they face the Computer-Based National Examination (UNBK). Participants in this study were students of class XII who received the highest score on the anxiety scale, meaning students with high and moderate anxiety levels. The instrument used was the DASS (Depression Anxiety Stress Scale) anxiety scale consisting of 42 statement items. The results of the preliminary study showed 60% of students experienced high levels of anxiety, and 30% were moderate and 10% experienced low levels of anxiety. Treatment performed on students is by using Progressive Relaxation Techniques for 6 sessions. Every 2x session an evaluation of the level of anxiety is completed. Students who are categorized as experiencing severe levels of anxiety and are being treated using this progressive relaxation method, they are given the task to do also relaxation at home every day before going to sleep and wake up. The results of the study after 6 progressive relaxation sessions, it was found that the level of anxiety of the students was reduced ie students who experienced severe anxiety levels were reduced to as much as 20%, who experienced moderate levels of anxiety to be completely gone. An effective Progressive Relaxation Technique is used to reduce the level of anxiety of students who will face the National Examination
Enteric Oxalate Secretion Mediated by Slc26a6 Defends against Hyperoxalemia in Murine Models of Chronic Kidney Disease
Authors: Neumeier Laura I. , Thomson Robert B. , Reichel Martin , Eckardt Kai-Uwe , Aronson Peter S. , Knauf Felix 
Published: July 2020

Significance Statement
Fecal oxalate excretion is critical in oxalate balance with progression of CKD. However, the identity of the transporter(s) responsible for increased intestinal oxalate secretion in CKD is unknown. Intestinal expression of oxalate transporter Slc26a6 is strongly upregulated in two murine models of CKD. Deletion of Slc26a6 completely abrogates enhanced fecal oxalate excretion in CKD, increasing plasma oxalate concentration. This study demonstrates that Slc26a6 mediates intestinal oxalate secretion and mitigates hyperoxalemia in murine CKD models. The findings suggest that pharmacologic approaches enhancing intestinal Slc26a6 activity may stimulate extrarenal clearance of oxalate and prevent hyperoxalemia in CKD. Future studies are needed to address whether similar mechanisms contribute to intestinal oxalate elimination in humans to enhance extrarenal oxalate clearance.

Background
A state of oxalate homeostasis is maintained in patients with healthy kidney function. However, as GFR declines, plasma oxalate (Pox) concentrations start to rise. Several groups of researchers have described augmentation of oxalate secretion in the colon in models of CKD, but the oxalate transporters remain unidentified. The oxalate transporter Slc26a6 is a candidate for contributing to the extrarenal clearance of oxalate via the gut in CKD.

Methods
Feeding a diet high in soluble oxalate or weekly injections of aristolochic acid induced CKD in age- and sex-matched wild-type and Slc26a6

−/−
mice. qPCR, immunohistochemistry, and western blot analysis assessed intestinal Slc26a6 expression. An oxalate oxidase assay measured fecal and Pox concentrations.

Results
Fecal oxalate excretion was enhanced in wild-type mice with CKD. This increase was abrogated in Slc26a6

−/−
mice associated with a significant elevation in plasma oxalate concentration. Slc26a6 mRNA and protein expression were greatly increased in the intestine of mice with CKD. Raising Pox without inducing kidney injury did not alter intestinal Slc26a6 expression, suggesting that changes associated with CKD regulate transporter expression rather than elevations in Pox.

Conclusions
Slc26a6-mediated enteric oxalate secretion is critical in decreasing the body burden of oxalate in murine CKD models. Future studies are needed to address whether similar mechanisms contribute to intestinal oxalate elimination in humans to enhance extrarenal oxalate clearance.
COVID-19–Associated Kidney Injury: A Case Series of Kidney Biopsy Findings
Authors: Sharma Purva , Uppal Nupur N. , Wanchoo Rimda , Shah Hitesh H. , Yang Yihe , Parikh Rushang , Khanin Yuriy , Madireddy Varun , Larsen Christopher P. , Jhaveri Kenar D. , Bijol Vanesa ,   on behalf of Northwell Nephrology COVID-19 Research Consortium
Published: July 2020

Significance Statement
AKI is a known complication of severe COVID-19. Autopsy series of patients who died with COVID-19 reported acute tubular necrosis in the kidney, and a few patient reports noted the presence of collapsing glomerulopathy in patients with COVID-19. The authors describe clinical and kidney histopathologic findings for ten hospitalized patients with COVID-19 and AKI who underwent kidney biopsy. All patients had proteinuria, and eight required dialysis. Biopsy samples showed varying degrees of acute tubular necrosis in all patients; one patient also had associated myoglobin cast nephropathy. Pathologic analysis of biopsied kidneys showed no immunohistochemical evidence of severe acute respiratory syndrome coronavirus 2, and ultrastructural examination found no viral particles. This case series reveals acute tubular necrosis as the most common kidney biopsy finding in patients with COVID-19 and severe AKI.

Background
Reports show that AKI is a common complication of severe coronavirus disease 2019 (COVID-19) in hospitalized patients. Studies have also observed proteinuria and microscopic hematuria in such patients. Although a recent autopsy series of patients who died with severe COVID-19 in China found acute tubular necrosis in the kidney, a few patient reports have also described collapsing glomerulopathy in COVID-19.

Methods
We evaluated biopsied kidney samples from ten patients at our institution who had COVID-19 and clinical features of AKI, including proteinuria with or without hematuria. We documented clinical features, pathologic findings, and outcomes.

Results
Our analysis included ten patients who underwent kidney biopsy (mean age: 65 years); five patients were black, three were Hispanic, and two were white. All patients had proteinuria. Eight patients had severe AKI, necessitating RRT. All biopsy samples showed varying degrees of acute tubular necrosis, and one patient had associated widespread myoglobin casts. In addition, two patients had findings of thrombotic microangiopathy, one had pauci-immune crescentic GN, and another had global as well as segmental glomerulosclerosis with features of healed collapsing glomerulopathy. Interestingly, although the patients had confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by RT-PCR, immunohistochemical staining of kidney biopsy samples for SARS-CoV-2 was negative in all ten patients. Also, ultrastructural examination by electron microscopy showed no evidence of viral particles in the biopsy samples.

Conclusions
The most common finding in our kidney biopsy samples from ten hospitalized patients with AKI and COVID-19 was acute tubular necrosis. There was no evidence of SARS-CoV-2 in the biopsied kidney tissue.
COVID-19, Racism, and Racial Disparities in Kidney Disease: Galvanizing the Kidney Community Response
Authors: Crews Deidra C. , Purnell Tanjala S. 
Published: July 2020

Podcast
This article contains a podcast athttps://www.asn-online.org/media/podcast/JASN/2020_07_21_JASN2020060809.mp3
Modifikasi Perilaku Anak: Implementasi Teknik Pengelolaan Diri dan Keterampilan Sosial di Ngawi Jawa Timur
Authors: Satriyawan Aziz Nuri , Ichsan Ahmad Shofiyuddin 
Published: July 2020

Penelitian ini bertujuan untuk mengungkap bagaimana teknik modifikasi perilaku anak dapat diubah, yakni mengubah perilaku maladaptif menuju perilaku adaptif. Penelitian ini adalah penelitian kualitatif yang dilakukan pada anak di Kenteng Sumberejo Sine Ngawi Jawa Timur dengan fokus kepada anak-anak yang memiliki perilaku maladaptif. Hasil penelitian ini mengungkapkan bahwa teknik modifikasi perilaku melalui pengelolaan diri dan pelatihan keterampilan sosial mampu mengubah perilaku anak, baik untuk mengantisipasi supaya tidak berperilaku negatif dengan menghilangkannya, maupun dapat menumbuh kembangkan perilaku yang positif bagi mereka. Maka dari itu, diperlukan komunikasi dan kerja sama antar masing-masing anggota keluarga melalui motivasi, pengertian, dan pengawasan yang dilakukan secara kontinyu. Hal ini demi terwujudnya modifikasi perilaku yang baik terhadap anak.
Estado actual del carcinoma in situ del cuello uterino, en el Hospital San Juan de Dios de Bogotá
Authors: Fonnegra Miramón Alvaro , Sarria Oleos Carlos E. 
Published: July 2020

Se hace una revision de 34 casos de Casos de in situ diagnosticados, tratados y controlados en el servicio de Ginecología en el Hospital San Juan de Dios de Bogotá.En este servicio como norma de conducta, una vez diagnosticado el Ca. pre-invasor por biopsia , se procede a practicar conización del cuello uterino para descartar por cortes seriados el carcinoma invasor. Ya con el resultado anatomopatológico de la conización se decide el próximo paso a seguir, que puede ser histerectomía o control de la paciente con citologías periódicas .
Cáncer de la vulva Revisión de 58 Casos atendidos en el Instituto Nacional de Cancerología desde 1934 hasta 1960
Authors: Jordan German , Darnalt Enrique , Quijano Hugo , Posada Hernán , Rodríguez Hernando 
Published: July 2020

En este trabajo se presenta el resultado de la revisión de las historias de 58 casos de enfermas con cáncer de vulva, atendidas en el Instituto Nacional de Cancerología hasta 1960.
The Exploration and Practice of the Construction of Higher Mathematics Teaching Resources in Application-Oriented Universities
Authors: Li Jianxiang 
Published: July 2020

<p>At present, informatiziation has become one of the important direction trends of education in colleges and universities. Under the background of education informatization, carrying out the construction of higher mathematics teaching resources in colleges and universities is of great significance for promoting the development of higher mathematics teaching in colleges and universities and improving the actual teaching quality. At present, there are still many deficiencies and problems in the construction of higher mathematics teaching resources in related application-oriented universities. Based on the current situation of higher mathematics teaching, this paper analyzes the problems existing in the construction of higher mathematics teaching resources and finds the countermeasures for the construction of higher mathematics teaching resources in application-oriented universities.</p>
The Discussion on the Countermeasures of Ideological and Political Education in College Students' Employment Guidance
Authors: Zhang Hong 
Published: July 2020

<p>At present, with a growing number of college graduates, the problem of employment of graduates has become one of the hot topics in society. Therefore, colleges and universities are positively arranging employment instruction work for college students, hoping to provide effective employment guidance for them to help them to better achieve employment. while in the ideas of undergraduates' employment and career choice, they are also facing a lot of confusion and contradiction. Consequently, it is necessary to strengthen ideological and political education in the employment guidance. This paper introduces the relationship between the university students' employment guidance and ideological and political education, analyzes the current situation of their ideological and political education in employment guidance, and explores the countermeasures to achieve effective ideological and political education in the employment guidance of college students.</p>
Thoughts on Teaching Reform of Audit Practice Course in Higher Vocational Colleges
Authors: Li Ling 
Published: July 2020

<p>As a core course of auditing practice, it plays an important role in the accounting profession of higher vocational colleges. This course is not only relatively difficult for students to learn, but teachers also face great challenges in the teaching process and reform auditing course . It is necessary to focus on the needs of auditing jobs and focus on training students' professional ability in auditing. Through reforming teaching methods, restructuring teaching content, scientific assessment and evaluation, etc., the working process of auditing practice can be truly reflected and the auditing practice course can be connected with Complete effective integration between actual work and earnestly improve students' professional ability.</p>
Research on the External Communication and Translation Studies of Traditional Chinese Medicine Culture under the Background of "One Belt and One Road "
Authors: Zou Fangde 
Published: July 2020

<p>Culture is the heritage of a country and a bridge of international exchanges. Under the background of "One Belt and One Road", strengthening the communication culture of traditional Chinese medicine to the world can not only achieve the revival of traditional Chinese medicine culture, but also become a brand new cultural business card for China. At the same time, it can make our country occupy a greater international influence. This article will specifically discuss the communication strategy of Chinese traditional medicine culture and its translation studies in the context of "One Belt and One Road ".</p>
Exploration on the Reform of Teaching Methods Aimingat Research-Based Learning under the Background of "Excellence Program"
Authors: Li Zhi , Zhang Yujiao , Luo Chaoxiang , Li Fangyu , Su Pan 
Published: July 2020

<p>The implementation of "excellence plan" promotes our country to become a powerful country in engineering education and promotes higher education to cultivate a large number of high-quality engineering, technical personnel with strong innovation ability and adapt to the needs of economic and social development, however the traditional teaching methods no longer meet the needs of training high-quality engineers. This article will research study and discipline teaching organically fuses in together. Firstly the teachers should improve their academic and teaching ability, and accumulate enterprise engineering practice experience, reform the teaching methods, in order to cause the students to independently discover problems, explore the problem and get conclusion under teacher's guidance, cultivating their engineering practice ability and innovation ability. The exploration of teaching reform has been carried out through the course "Operation and Maintenance of Overhead Transmission Lines", which has achieved good results and will be continuously improved.</p>
On the mapping of especially valuable agricultural lands
Authors: Savin I. Yu. , Psareva A. P. 
Published: July 2020

Delineation of especially valuable agricultural lands (EVAL) is currently an important task, which will make it possible to preserve agricultural land for its direct use. There are currently no uniform approaches for delineation of EVAL, or they need to be upgraded. We have proposed a new approach based on GIS modeling and simulation of agricultural plant growth. It is proposed to delineate EVAL for each municipal district taking into account its existing specialization in agricultural production. The allocation of EVAL should be based on the assessment of potential productivity of soils and lands for cultivation of the main crops in the district. EVAL should also include pilot fields and areas used for scientific and educational purposes, regardless of potential soil productivity. The proposed approach has been successfully tested on the example of Yasnogorsk district of Tula region. It is shown that the EVAL map, based on the proposed approach, is more related to the actual land productivity and does not depend on the current land use within the area. It is possible to build an EVAL map for the whole country only by building such maps separately for all municipal districts of Russia.