bluuebunny/crossref_metadata_2025_split huggingface dataset:
Word reading in English and Arabic in children who are Syrian refugees
Authors: Gottardo Alexandra , Amin Norah , Amin Asma , Al-Janaideh Redab , Chen Xi , Paradis Johanne 
Published: August 2020

AbstractWord reading is a fundamental skill in reading and one of the building blocks of reading comprehension. Theories have posited that for second language (L2) learners, word reading skills are related if the children have sufficient experience in the L2 and are literate in the first language (L1). The L1 and L2 reading, phonological awareness skills, and morphological awareness skills of Syrian refugee children who speak Arabic and English were measured. These children were recent immigrants with limited L2 skills and varying levels of L1 education that was often not commensurate with their ages. Within- and across-language skills were examined in 96 children, ages 6 to 13 years. Results showed that phonological awareness and morphological awareness were strong within-language variables related to reading. Additionally, Arabic phonological awareness and morphological processing were strongly related to English word reading. Commonality analyses for variables within constructs (e.g., phonological awareness, morphological awareness) but across languages (Arabic and English) in relation to English word reading showed that in addition to unique variance contributed by the variables, there was a high degree of overlapping variance.
Policy programme cycles through old and new programmatic groups
Authors: Bandelow Nils C. , Hornung Johanna 
Published: August 2020

AbstractThis article draws on the Programmatic Action Framework (PAF) to tackle the question of how the dominance and decline of a specific policy programme in a policy sector can be explained. It starts from the observation that visionary policy programmes, defined as a set of policy goals and instruments that find their expression in subsequently adopted and interconnected policy reforms, may shape a sector’s policies over several decades. Linking policy programmes to programmatic groups that promote these programmes in search of boosting their careers and authority, the programme’s rising and declining dominance can be explained by the career trajectories of programmatic actors. By displaying empirical evidence for the argument from German health policy, the article shows that proponents of today’s change are opponents of tomorrow’s change since individual careers depend on the dominance of policy programmes.
Crosslinguistic influence and L2 grammar learning: Proposed replications of Ellis and Sagarra (2011) and Tolentino and Tokowicz (2014)
Authors: McManus Kevin 
Published: August 2020

AbstractInvestigations of crosslinguistic effects in second language acquisition (SLA) have contributed rich understandings about the ways in which prior language knowledge and experience can influence additional language learning. Building on this work, one recent line of research has examined the extent to which SLA findings about crosslinguistic influence can be used to improve L2 learning, indicating that explicit instruction tailored to address the nature of the crosslinguistic learning problem can benefit L2 performance. At the same time, however, this line of inquiry is relatively novel and under-researched. The aim of this paper, therefore, is to suggest further research which might advance knowledge and understanding about the ways in which explicit instruction can facilitate second language (L2) learning of crosslinguistically difficult target features. To this end, I lay the ground for a series of close replications designed to understand the role of prior language knowledge and experience in L2 learning: Ellis and Sagarra (2011) and Tolentino and Tokowicz (2014). These studies were selected because they are grounded in empirical SLA research and SLA theory. In addition, the selected studies facilitate replication because they have either (i) made their data collection materials available in digital repositories or (ii) have robustly described their design and provided the stimuli used.
Impact of rarity on Canadian oncology health technology assessment and funding
Authors: Keech James , Dai Wei Fang , Trudeau Maureen , Mercer Rebecca E. , Naipaul Rohini , Wright Frances C. , Ferguson Sarah E. , Darling Gail , Gavura Scott , Eisen Andrea , Kouroukis C. Tom , Beca Jaclyn , Chan Kelvin K.W. 
Published: August 2020

ObjectivesThe pan-Canadian Oncology Drug Review (pCODR) evaluates new cancer drugs for public funding recommendations. While pCODR's deliberative framework evaluates overall clinical benefit and includes considerations for exceptional circumstances, rarity of indication is not explicitly addressed. Given the high unmet need that typically accompanies these indications, we explored the impact of rarity on oncology HTA recommendations and funding decisions.MethodsWe examined pCODR submissions with final recommendations from 2012 to 2017. Incidence rates were calculated using pCODR recommendation reports and statistics from the Canadian Cancer Society. Indications were classified as rare if the incidence rate was lower than 1/100,000 diagnoses, a definition referenced by the Canadian Agency for Drugs and Technologies in Health. Each pCODR final report was examined for the funding recommendation/justification, level of supporting evidence (presence of a randomized control trial [RCT]), and time to funding (if applicable).ResultsOf the ninety-six pCODR reviews examined, 16.6 percent were classified as rare indications per above criteria. While the frequency of positive funding recommendations were similar between rare and nonrare indication (78.6 vs. 75 percent), rare indications were less likely to be presented with evidence from RCT (50 vs. 90 percent). The average time to funding did not differ significantly across provinces.ConclusionRare indications appear to be associated with weaker clinical evidence. There appears to be no association between rarity, positive funding recommendations, and time to funding. Further work will evaluate factors associated with positive recommendations and the real-world utilization of funded treatments for rare indications.
A tale of three cities: urban and cultural resilience and heritage between the Late Bronze Age and Early Iron Age in the eastern Mediterranean
Authors: Middleton Guy D. 
Published: August 2020

AbstractThe turbulent years aroundc. 1200 BC in the eastern Mediterranean are known as a period of the collapse of states and empires. Yet by zooming in on three important royal cities, Tiryns, Hattusa and Carchemish, we can question this collapse narrative whilst at the same time exploring the now popular concept of resilience, in this case urban and cultural resilience. First these ancient cities are presented as interactive and meaningful spaces in which architecture and art were used to shape people's experience of them and the world in which they lived, before their urban fabric and functions are examined in turn. It will become clear that they had radically different fates throughc. 1200 BC. Some of the difficulties in applying ideas from resilience thinking and how it might or might not be useful as an approach in studying these and other examples are then discussed.
Analyses of High‐Iron Sedimentary Bedrock and Diagenetic Features Observed With ChemCam at Vera Rubin Ridge, Gale Crater, Mars: Calibration and Characterization
Authors: David G. , Cousin A. , Forni O. , Meslin P.‐Y. , Dehouck E. , Mangold N. , L'Haridon J. , Rapin W. , Gasnault O. , Johnson J. R. , Ollila A. M. , Newell A. R. , Salvatore M. , Gabriel T. S. J. , Wiens R. C. , Maurice S. 
Published: August 2020

AbstractCuriosity investigated a topographic rise named Vera Rubin Ridge (VRR) in Gale Crater, for which a distinct hematite‐like signature was observed from orbit. However, the Chemistry and Camera (ChemCam) and Alpha Particle x‐ray Spectrometer (APXS) instruments on board the rover did not record any significant iron enrichment in the bulk of the ridge compared to previous terrains. For this study, we have reverified ChemCam iron calibration at moderate abundances and developed more accurate calibrations at high‐iron abundances using iron‐oxide mixtures in a basaltic matrix in order to complete the ChemCam calibration database. The high‐iron calibration was first applied to the analysis of dark‐toned diagenetic features encountered at several locations on VRR, which showed that their chemical compositions are close to pure anhydrous iron oxides. Then, we tracked iron abundances in the VRR bedrock and demonstrated that although there is no overall iron enrichment in the bulk of the ridge (21.2 ± 1.8‐wt.% FeOT) compared to underlying terrains, the iron content is more variable in its upper section with areas of enhanced iron abundances in the bedrock (up to 26.6 ± 0.85‐wt.% FeOT). Since the observed variability in iron abundances does not conform to the stratigraphy, the involvement of diagenetic fluid circulation was likely. An in‐depth chemical study of these Fe‐rich rocks reveals that spatial gradients in redox potential (Eh) may have driven iron mobility and reactions that precipitated and accumulated iron oxides. We hypothesize that slightly reducing fluids were probably involved in transporting ferrous iron. Mobile Fe2+ could have precipitated as iron oxides in more oxidizing conditions.
Abrupt Climate and Weather Changes Across Time Scales
Authors: Lohmann Gerrit , Butzin Martin , Eissner Nina , Shi Xiaoxu , Stepanek Christian 
Published: August 2020

AbstractThe past provides evidence of abrupt climate shifts and changes in the frequency of climate and weather extremes. We explore the nonlinear response to orbital forcing and then consider climate millennial variability down to daily weather events. Orbital changes are translated into regional responses in temperature, where the precessional response is related to nonlinearities and seasonal biases in the system. We question regularities found in climate events by analyzing the distribution of interevent waiting times. Periodicities of about 900 and 1,150 yr are found in ice cores besides the prominent 1,500 yr cycle. However, the variability remains indistinguishable from a random process, suggesting that centennial‐to‐millennial variability is stochastic in nature. New numerical techniques are developed allowing for a high resolution in the dynamically relevant regions like coasts, major upwelling regions, and high latitudes. Using this model, we find a strong sensitivity of the Atlantic meridional overturning circulation depending on where the deglacial meltwater is injected into. Meltwater into the Mississippi and near Labrador hardly affect the large‐scale ocean circulation, whereas subpolar hosing mimicking icebergs yields a quasi shutdown. The same multiscale approach is applied to radiocarbon simulations enabling a dynamical interpretation of marine sediment cores. Finally, abrupt climate events also have counterparts in the recent climate records, revealing a close link between climate variability, the statistics of North Atlantic weather patterns, and extreme events.
Atmospheric Dynamics Patterns in Southern Central Asia Since 800 ka Revealed by Loess‐Paleosol Sequences in Tajikistan
Authors: Lu Hao , Jia Jia , Yin Qiuzhen , Xia Dunsheng , Gao Fuyuan , Liu Hao , Fan Yijiao , Li Zaijun , Wang Xin , Berger André , Oimuhammadzoda Ilhomjon , Gadoev Mustafo 
Published: August 2020

AbstractThe atmospheric mechanisms responsible for the loess grain‐size variations in central Asia are less clear, and an increasing number of studies have found that the coarse‐grained component is likely supplied by the surface circulation rather than by the westerlies (westerlies circulation). In this study, we attempt to determine the atmospheric dynamics patterns in the Afghan‐Tajik Basin during the past 800 kyr, based on the coarse grain‐size fraction of loess, combined with a study of modern dust transport processes. We suggest that the coarse grain‐size fraction can be used to indicate the intensity of near‐surface winds, while on glacial‐interglacial time scales, the variations of loess grain size in Tajikistan are dominated by Northern Hemisphere ice volume via its effect on the strength of the Siberian High. In addition, we suggest that atmospheric greenhouse gases concentration affected the loess grain size during interglacials via their influence on the temperature of southern high latitudes.
Modeling Marsh‐Forest Boundary Transgression in Response to Storms and Sea‐Level Rise
Authors: Carr J. , Guntenspergen G. , Kirwan M. 
Published: August 2020

AbstractThe lateral extent and vertical stability of salt marshes experiencing rising sea levels depend on interacting drivers and feedbacks with potential for nonlinear behaviors. A two‐dimensional transect model was developed to examine changes in marsh and upland forest lateral extent and to explore controls on marsh inland transgression. Model behavior demonstrates limited and abrupt forest retreat with long‐term upland boundary migration rates controlled by slope, sea‐level rise (SLR), high water events, and biotic‐abiotic interactions. For low to moderate upland slopes the landward marsh edge is controlled by the interaction of these inundation events and forest recovery resulting in punctuated transgressive events. As SLR rates increase, the importance of the timing and frequency of water‐level deviations diminishes, and migration rates revert back to a slope‐SLR‐dominated process.
Quantification of the Atmospheric Relativistic Electron Precipitation on 17 January 2013
Authors: Shekhar S. , Millan R. M. , Woodger L. A. , Qin M. 
Published: August 2020

AbstractOn 17 January 2013, relativistic electron precipitation (REP) was observed on Balloon Array for Radiation Belt Relativistic Electron Losses (BARREL) payloads, National Oceanic and Atmospheric Administration Polar orbiting Operational Environmental Satellites (NOAA POES), and European Space Agency (ESA) MetOp between 2:44 to 15:04 h UT, scattered across dusk to early morning magnetic local time (MLT) sectors. The observations could be grouped into multiple observations of seven REP events spatially separated by more than 2 h in MLT and at least 1 h in UT. Almost all the events were localized in L shell with dL < 0.5 and MLT with dMLT < 3. A net loss of ∼5% of the relativistic electrons from the radiation belts is estimated between 2:44 to 15:04 h UT (∼13.5 h). A majority of atmospheric REP (nearly 75% through six REP events) was observed before the onset of a minor storm around 14:00 UT; the rest (25% through one REP event) was observed during the commencement of the storm which was followed by a major dropout of MeV electrons from the radiation belts during the main phase. However, no atmospheric precipitation was observed during the main phase, indicating that the dropouts may not have been caused by particle loss into the atmosphere.
Rheological Weakening of Olivine + Orthopyroxene Aggregates Due to Phase Mixing: Effects of Orthopyroxene Volume Fraction
Authors: Tasaka Miki , Zimmerman Mark E. , Kohlstedt David L. 
Published: August 2020

AbstractTo understand the effects of secondary minerals on changes in the mechanical properties of upper mantle rocks due to phase mixing, we conducted high‐strain torsion experiments on aggregates of iron‐rich olivine + orthopyroxene (opx) with opx volume fractions of fopx = 0.15, 0.26, and 0.35. For samples with larger amounts of opx, fopx = 0.26 and 0.35, the value of the stress exponent decreases with increasing strain from n ≈ 3 for γ ≲ 5 to n ≈ 2 for 5 ≲ γ ≲ 25, indicating that the deformation mechanism changes as strain increases. In contrast, for samples with fopx = 0.15, the stress exponent is constant at n ≈ 3.3 for 1 ≲ γ ≲ 25, suggesting that no change in deformation mechanism occurs with increasing strain for samples with smaller amounts of opx. The microstructures of samples with larger amounts of opx provide insight into the change in deformation mechanism derived from the mechanical data. Elongated grains align subparallel to the shear direction for samples of all three compositions deformed to lower strains. However, strain weakening with grain size reduction and the formation of a thoroughly mixed, fine‐grained texture only develops in samples with fopx = 0.26 and 0.35 deformed to higher strains of γ ≳ 16. These mechanical and associated microstructural properties imply that rheological weakening due to phase mixing only occurs in the samples with larger fopx, which is an important constraint for understanding strain localization in the upper mantle of Earth.
Temperature‐Dependent Optical Properties of Liquid Water From 240 to 298 K
Authors: Rowe P. M. , Fergoda M. , Neshyba S. 
Published: August 2020

AbstractClouds play a key role in Earth's radiative balance. Radiative transfer through liquid clouds depends on the optical properties of liquid water. Although these optical properties are known to be temperature dependent, radiative transfer simulations typically use properties based on measurements made at 298 K, even for supercooled liquid clouds at temperatures as low as 240 K. Here we report temperature‐dependent complex refractive indices (CRIs) of liquid water at 240, 253, 263, and 273 K from 1 to 15,000 cm−1 (0.7 to 10,000 μm). Imaginary parts of the CRI (k) are inferred from values reported in the literature for temperatures of 238 to 298 K and the real parts are obtained via Kramers‐Kronig transformation. Mie theory is used to calculate single scattering albedos and Legendre moments from the CRI, producing a set of optical constants suitable for radiative transfer calculations through supercooled liquid cloud at temperatures as low as 240 K. Ignoring the temperature dependence of complex refractive indices of liquid water is thereby found to result in biased‐high supercooled liquid‐cloud fluxes from 250 to 580 cm−1 and biased‐low fluxes from 710 to 940 cm−1.
LncRNA DANCR and miR-320a suppressed osteogenic differentiation in osteoporosis by directly inhibiting the Wnt/β-catenin signaling pathway
Authors: Wang Cheng-Gong , Hu Yi-He , Su Shi-Long , Zhong Da 
Published: August 2020

AbstractOur study aimed to determine how lncRNA DANCR, miR-320a, and CTNNB1 interact with each other and regulate osteogenic differentiation in osteoporosis. qRT-PCR and western blotting were performed to determine the expression of DANCR, miR-320a, CTNNB1, and the osteoporosis- or Wnt/β-catenin pathway-related markers T-cell factor 1 (TCF-1), runt-related transcription factor 2 (RUNX2), alkaline phosphatase (ALP), osteocalcin (OCN), and osteopontin (OPN). Interactions between CTNNB1, DANCR, and miR-320a were predicted by bioinformatics approaches and validated using a luciferase assay. Osteoblastic phenotypes were evaluated by ALP staining, ALP activity assay and Alizarin Red staining. The bilateral ovariectomy method was used to establish an in vivo osteoporosis model. Bone morphological changes were examined using hematoxylin and eosin (H&E) and Alcian Blue staining. The expression levels of DANCR and miR-320a in BMSCs derived from osteoporosis patients were upregulated, whereas CTNNB1 expression was downregulated compared with that in healthy controls. Importantly, we demonstrated that miR-320a and DANCR acted independently from each other and both inhibited CTNNB1 expression, whereas the inhibitory effect was additive when miR-320a and DANCR were cooverexpressed. Moreover, we found that DANCR overexpression largely abrogated the effect of the miR-320a inhibitor on CTNNB1 expression and the Wnt/β-catenin signaling pathway in BMSCs during osteogenic differentiation. We further confirmed the results above in BMSCs derived from an osteoporosis animal model. Taken together, our findings revealed that DANCR and miR-320a regulated the Wnt/β-catenin signaling pathway during osteogenic differentiation in osteoporosis through CTNNB1 inhibition. Our results highlight the potential value of DANCR and miR-320a as promising therapeutic targets for osteoporosis treatment.
Diffraction-limited imaging with monolayer 2D material-based ultrathin flat lenses
Authors: Lin Han , Xu Zai-Quan , Cao Guiyuan , Zhang Yupeng , Zhou Jiadong , Wang Ziyu , Wan Zhichen , Liu Zheng , Loh Kian Ping , Qiu Cheng-Wei , Bao Qiaoliang , Jia Baohua 
Published: August 2020

AbstractUltrathin flat optics allow control of light at the subwavelength scale that is unmatched by traditional refractive optics. To approach the atomically thin limit, the use of 2D materials is an attractive possibility due to their high refractive indices. However, achievement of diffraction-limited focusing and imaging is challenged by their thickness-limited spatial resolution and focusing efficiency. Here we report a universal method to transform 2D monolayers into ultrathin flat lenses. Femtosecond laser direct writing was applied to generate local scattering media inside a monolayer, which overcomes the longstanding challenge of obtaining sufficient phase or amplitude modulation in atomically thin 2D materials. We achieved highly efficient 3D focusing with subwavelength resolution and diffraction-limited imaging. The high focusing performance even allows diffraction-limited imaging at different focal positions with varying magnifications. Our work paves the way for downscaling of optical devices using 2D materials and reports an unprecedented approach for fabricating ultrathin imaging devices.
Computational causal discovery for post-traumatic stress in police officers
Authors: Saxe Glenn N. , Ma Sisi , Morales Leah J. , Galatzer-Levy Isaac R. , Aliferis Constantin , Marmar Charles R. 
Published: August 2020

AbstractThis article reports on a study aimed to elucidate the complex etiology of post-traumatic stress (PTS) in a longitudinal cohort of police officers, by applying rigorous computational causal discovery (CCD) methods with observational data. An existing observational data set was used, which comprised a sample of 207 police officers who were recruited upon entry to police academy training. Participants were evaluated on a comprehensive set of clinical, self-report, genetic, neuroendocrine and physiological measures at baseline during academy training and then were re-evaluated at 12 months after training was completed. A data-processing pipeline—the Protocol for Computational Causal Discovery in Psychiatry (PCCDP)—was applied to this data set to determine a causal model for PTS severity. A causal model of 146 variables and 345 bivariate relations was discovered. This model revealed 5 direct causes and 83 causal pathways (of four steps or less) to PTS at 12 months of police service. Direct causes included single-nucleotide polymorphisms (SNPs) for the Histidine Decarboxylase (HDC) and Mineralocorticoid Receptor (MR) genes, acoustic startle in the context of low perceived threat during training, peritraumatic distress to incident exposure during first year of service, and general symptom severity during training at 1 year of service. The application of CCD methods can determine variables and pathways related to the complex etiology of PTS in a cohort of police officers. This knowledge may inform new approaches to treatment and prevention of critical incident related PTS.