bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Metabolic Syndrome amongst Saudi Arabian Women with Polycystic Ovarian Syndrome: A Cross-sectional Study
Authors: Alkathem Jafar Ali , Alawwad Htoon Abdulltif , Alghamdi Tafe Safar , Majrashy Alya Ebrahim Hady , Algarni Shahad Ayed , Aljabari Latifah Abdulwahab , Al-Alwan Mohammed Khalid , Ahmed Rufaida A. 
Published: December 2024

Abstract

Introduction:
Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder amongst the women of reproductive age. Metabolic syndrome represents a cluster of abdominal obesity, dyslipidaemia, hypertension and insulin resistance that increases cardiovascular risks. Evidence suggests a link between PCOS and metabolic syndrome; however, limited data exist on their coexistence amongst Saudi Arabian women. This study aimed to investigate the prevalence of metabolic syndrome amongst Saudi women with PCOS.

Methods:
A cross-sectional study recruited 1452 Saudi women diagnosed with PCOS from various clinics. Data were collected using a validated questionnaire assessing demographics, PCOS/metabolic syndrome diagnoses, symptoms, management and awareness. Descriptive statistics characterised the sample. The Chi-square tests examined the associations between PCOS and metabolic parameters.

Results:
The sample comprised 1452 women aged 18–64 years old. 54.5% had PCOS diagnosis while 1.7% had metabolic syndrome. Thirty-eight per cent reported no metabolic symptoms. A significant association was found between PCOS and metabolic syndrome diagnoses (P < 0.001). Regarding metabolic parameters, 24.8% underwent insulin resistance tests, 0.8% had dyslipidaemia diagnosis and 34.7% measured waist circumference. Sixty-two per cent observed no insulin resistance changes and 68.6% no lipid changes. 28.1% agreed on the relationship between metabolic syndrome and insulin resistance, dyslipidaemia and central obesity. 41.3% had some awareness on metabolic consequences.

Conclusion:
The study identified notable metabolic syndrome prevalence amongst Saudi women with PCOS, denoting their clinical interconnection. Metabolic syndrome exhibited associations with insulin resistance, dyslipidaemia and central obesity. Lifestyle modifications were commonly adopted for management despite relatively low awareness levels.
Evaluation of anthracycline-induced cardiotoxicity using cardiac biomarkers: A prospective study
Authors: Prasad Krishna , Yadav Budhi Singh , Zohmangaihi Deepy , Ballari Nagarjun , Mehrotra Saurabh 
Published: December 2024

Abstract

Background:
Though anthracyclines are the commonly used chemotherapeutics for cancer treatment, close monitoring of patients is required due to its well reported cardiotoxicity. The present study evaluates the role of biomarkers [N-terminal pro–B-type natriuretic peptide (NT-proBNP) and high sensitivity cardiac troponin-T (hs-cTnT)] in early prediction of cardiotoxicity in patients with breast and ovarian cancer who received anthracyclines.

Methods:
This was a single-center observational study conducted between August-2018 and January-2020. Doxorubicin was used as an anthracycline at a dose of 50 mg/m2 per cycle. All the patients underwent echocardiography before the start and at 3 months, 6 months and 12 months after chemotherapy. NT-proBNP and hs-cTnT levels were measured before as baseline and within 24 hours of the first and last cycle of anthracycline-based chemotherapy.

Results:
A total of 72 patients with breast and ovarian cancer participated in the study. The mean age of patients was 49.4 ± 10.3 years. Sixty six (91.7%) patients had breast cancer and 9 (12.5%) patients developed cardiotoxicity. Mean age of the patients who developed cardiotoxicity was 55.00 ± 12.5 years. The level of NT-proBNP and hs-cTnT were significantly increased after the last cycle of anthracycline in patients who developed cardiotoxicity.

Conclusion:
The measurement of NT-proBNP and hs-cTnT levels after anthracycline administration helps detect early sub-clinical cardiotoxicity and thus can assist in modification of therapeutic regimens and initiation of heart failure therapy to prevent future cardiac events.
In vitro analysis of compressive strength of root dentin on application of intracanal medicaments for different time periods
Authors: Ghosh Kushal Kumar , Mukherjee Sayantan , Mazumdar Paromita , Ali Sahil , Das Lovely 
Published: December 2024

Background:
Extended application of intracanal medicaments such as calcium hydroxide (CH) and triple antibiotic paste (TAP) is documented to reduce dentin’s resistance to fracture.

Aim:
This study intended to evaluate the resistance to fracture of root dentin treated with different medicaments – CH, TAP, CH with chlorhexidine (CHX) and lycopene (LP), and chitosan acetate (CA) – over 7, 14, and 42 days.

Materials and Methods:
Seventy-five single-rooted human mandibular premolars were biomechanically prepared and categorized into five groups based on the medicament used, with further subdivision based on application duration. Fracture resistance was tested after each time interval.

Statistical Analysis:
Within-group comparisons were analyzed using repeated measures analysis of variance (ANOVA), while inter-group comparisons used a one-way ANOVA test at a 5% significance level.

Results:
At 7 days, no statistically notable differences were found among the groups. However, by day 14 and day 42, the groups treated with CH and TAP exhibited significantly reduced fracture resistance compared to the other groups.

Conclusion:
Combining LP with CH and CHX, or using CA, did not reduce radicular dentin fracture resistance, unlike TAP and CH. These findings suggest LP and CA as viable alternatives, potentially minimizing the adverse effects of traditional treatments.
Comparison of double antibiotic chitosan hydrogel scaffold with platelet-rich fibrin in regeneration in immature necrotic permanent teeth – Randomized controlled trial
Authors: Mittal Neelam , Baranwal Harakh Chand , Aggarwal Harshitaa , Kharat Shubham , Samad Silviya , Ayubi Aiyman 
Published: December 2024

Background:
Fibrin, a natural hydrogel, can act as scaffold for tissue regeneration. Antibiotic-loading of hydrogels can create an infection-free environment for stem cell proliferation and maturation.

Aim:
To compare regenerative endodontic potential of three groups (antibiotic-loaded hydrogel, chitosan-loaded hydrogel, and double antibiotic-loaded chitosan hydrogel) in immature necrotic permanent teeth with platelet rich fibrin (PRF).

Materials and Methods:
Fifty-six immature necrotic teeth with periapical lesions were included in simple randomized parallel-controlled superiority trial. Patients aged 10–35 years were assigned into four groups based on scaffolds used: Group 1 (PRF), Group 2 (double antibiotic-loaded [metronidazole and ciprofloxacin] chitosan hydrogel), Group 3 (double antibiotic-loaded hydrogel), and Group 4 (chitosan-loaded hydrogel). One patient per group was lost to follow-up. Regenerative outcomes (change in apex size, root length, radicular dentin thickness, and periapical healing) were assessed at 12 months, through double-blinding and compared postprocedure using cone-beam computed tomography.

Statistical Analysis:
Based on normality distribution, change in apex size (ANOVA test) while root length, radicular dentin thickness (Kruskal–Wallis test), and periapical healing (paired t-test) were used.

Results:
Group 2 showed superior regenerative outcomes (P = 0.001) compared to groups 1, 4 after 12 months, and no significant difference with Group 3.

Conclusion:
Double antibiotic-loaded chitosan produced significantly superior outcomes compared to PRF in promoting apexogenesis in immature permanent teeth with necrosed pulp.
Comparative evaluation of apical microleakage of mineral trioxide aggregate, Biodentine, and Bio-C Repair as root-end filling materials using dye extraction method: An in vitro study
Authors: Kunam Divya , Bode Yamuna , Narra Pavanila Meghana , Krishna C. H. N. V. Murali , Reddy Satti Narayana , Venkateshwarlu Modem 
Published: December 2024

Context:
Root-end filling materials enhance the apical sealing ability of the root canal to avoid leakage of irritants and to prevent the reentering of microorganisms.

Aim:
The objective of the present study was to compare and evaluate apical microleakage in retrograde filling materials with mineral trioxide aggregate (MTA), Biodentine, and Bio-C Repair using an ultraviolet (UV)–visible spectrophotometer.

Materials and Methods:
Fifty maxillary incisors were selected and decoronated. Instrumentation was done with ProTaper rotary files and obturated with AH Plus sealer and ProTaper gutta-percha cone using lateral condensation technique. The apical part of each root was resected at 90° to the long axis of the root for 3 mm, and retrograde cavity preparation was done up to 3 mm using an ultrasonic retro tip. After conditioning the root end with 17% ethylenediaminetetraacetic acid, the teeth were divided into four groups. Group 1 = Positive Control (n = 5), Group 2 was filled with MTA (n = 15), Group 3 was filled with Biodentine (n = 15), and Group 4 was filled with Bio-C Repair (n = 15). All samples were incubated in 5 mL of 2% methylene blue dye for 72 h after which teeth were immersed in 65% nitric acid for 72 h. The solutions were then filtered using fine grit filter paper and centrifuged at 3500 rpm for 5 min. The solution thus collected was used to determine absorbency in UV–visible spectrophotometer at 550 nm.

Statistical Analysis:
The data were analyzed using one-way analysis of variance and Tukey post hoc tests. P <0.05 was considered significant for all analyses.

Results:
The results showed that Biodentine had the least dye absorbance, which means less microleakage, and there was no significant difference between MTA and Bio-C Repair.

Conclusion:
Biodentine showed superior sealing ability as a retrograde filling material compared to Bio-C Repair and MTA.
The fracture resistance of restored mandibular molars using different cavity designs: An in vitro comparative evaluation
Authors: Mitra Aditya , Sharma Snigdha , Bhattacharyya Anirban , Maity Asim Bikash , Majumder Gayatri , Datta Soham 
Published: December 2024

Background:
The stress distribution of a restored tooth is different from that of an intact sound tooth. The fracture resistance of a restored tooth depends on cavity design, remaining tooth structure, and material used.

Aim:
This in vitro study evaluated and compared the fracture resistance of mandibular molars restored using composite resin.

Materials and Methods:
Forty freshly extracted, intact mandibular molars were used, with their roots embedded in acrylic resin for stability. Cavities were prepared using a No. 2 round bur and straight fissure diamond, then divided into four groups with specific variations in cavity dimensions. Samples were tested using a universal testing machine, applying vertical load along the long axis at the central fossa to record fracture load.

Statistical Analysis:
One-way analysis of variance and Tukey’s post hoc analysis were used for statistical analysis.

Results:
Fracture resistance of the groups, listed in descending order, was: Lingual wall 1.5 mm (2417 ± 160 N) > Buccal wall 1.5 mm (2122 ± 75.9 N) > Lingual wall 1 mm (1966 ± 75.7 N) > Buccal wall 1 mm (1335 ± 216 N).

Conclusion:
The lingual wall 1.5 mm exhibited the highest fracture resistance, while the buccal wall with 1 mm thickness showed the least resistance.
Does Universal Health Coverage Include the Caregivers? A Mixed Method Study on Accessibility and Out-of-pocket Expenditure for Healthcare Services by Accredited Social Health Activists of North India
Authors: Singh Mitasha , Aparnavi Periasamy , Dagar Rakesh , Yadav Kriti , Vig Shankar Lal , Reddy Kallem Dheeraj 
Published: December 2024

Abstract

Background:
Despite the load of voluntary work done by Accredited Social Health Activists (ASHAs), they are not recognized and are not provided any health security measures. The current study aims to estimate the proportion of income spent on healthcare services by ASHA and her family in the past 6 months and to explore their access to healthcare services.

Methods:
A mixed-method study was done among ASHAs under one community health center in North India in 2022. A self-administered questionnaire was used to collect data on the healthcare preferences and expenses of the ASHAs and their family. In the second phase, focused group discussions were conducted among the ASHAs in groups of 6–8 to collect data on their experiences with healthcare services. One of the co-investigators was the moderator, another was conducting audio recordings and taking notes.

Results:
Eighteen ASHAs were included in the study, and 38.8% of them had health insurance. For preventive services, they preferred community health centers (CHCs) (83.3%). Health expenses in the past 6 months were about 12.18% of their family income. The focused group discussion was based on themes including ASHAs’ expectations from the system they are working with, their healthcare-seeking behavior, and both of its effects on their performance in the implementation of the target-oriented program at the ground level.

Conclusion:
Being part of the health system, the community health worker is aware of the quality of services provided. Not preferring the public health system was reported due to disrespect in the system and unavailability of some curative services.
Multitude Symptoms in a Case of Giant Neurocysticercosis: A Case Report with Review of Literature
Authors: Singh Anurag , Verma Anuragani , Rawat Shalini , Sagar Mala 
Published: December 2024

Abstract
Neurocysticercosis (NCC) is a parasitic infection that affects the central nervous system and is caused by the larval stage of the pork tapeworm Taenia solium. There are two forms in the brain: parenchymal and extra-parenchymal, also known as racemose. The clinical manifestation of cysticercosis cysts is quite variable and varies significantly from one patient to another. Diagnosing NCC clinically is difficult; however, the introduction of advanced brain imaging techniques has improved the accuracy of diagnosis. The primary focus of this case study was to re-emphasize its multitude of manifestations and include a discussion of the diagnostic modalities and treatment options.
Asymmetric Herpes Zoster Duplex Bilateralis in an Immunocompetent Patient
Authors: Sharma Abhishek 
Published: December 2024

Abstract
Herpes zoster (HZ) is a common disorder of elderly patients presenting to primary care physicians and dermatologists. It is classically confined to a single dermatome but two or more contiguous dermatomes are often involved in immunocompromised patients and less frequently in immunocompetent patients. However, the simultaneous occurrence of HZ at two noncontiguous dermatomes is rare and is called HZ duplex (HZD). The dermatomes involved can be unilateral which is termed HZD unilateralis or bilateral which is termed HZD bilateralis (HZDB). These atypical manifestations are rarely reported in immunocompetent as well as immunosuppressed patients. We report a case of asymmetric HZDB in a 51-year-old immunocompetent patient, which is very rare.
Fusing Attention and Convolution: A Hybrid Model for Brain Stroke Prediction
Authors: Bhuvanya R. , Kujani T. , Sivakumar K. 
Published: December 2024

INTRODUCTION: A stroke, a sudden interruption of blood flow to the brain, is a leading cause of disability and death. Early diagnosis is paramount for minimizing brain damage and maximizing treatment effectiveness.OBJECTIVES: Traditional diagnostic methods can be time-consuming and have limited Accuracy. METHODS: This study investigates the efficacy of various machine-learning models for stroke prediction. Specifically, it compares established models like K-Nearest Neighbor, Artificial Neural Network, Long Short Term Memory (LSTM), and stacked LSTM with a newly proposed Transformer Convolutional Neural Network (TCNN) architecture, which fuses Transformer and Convolutional neural network (CNN) models.RESULTS: The TCNN demonstrates significant promise, achieving a superior accuracy of 98% when optimized with the AMSGrad optimizer.CONCLUSION: These findings suggest that the TCNN architecture has the potential to revolutionize stroke prediction accuracy compared to existing methods, potentially leading to improved patient outcomes.
UP‐Net: A multi‐head architecture for reading and efficiently segmenting distorted QR codes
Authors: Parcham Ebrahim , Ilbeygi Mahdi , Hajipour Vahid , Gharaei Ali , Mokhtari Mahdi , Foroutan Mostafa 
Published: December 2024

AbstractSemantic segmentation is essential in machine vision but susceptible to noise and distortions that often appear in real‐world images. We propose UPlus‐Net (UP‐Net), a deep‐learning architecture based on the U‐Net encoder–decoder architecture. We address the limitations of U‐Net by introducing a multi‐head architecture in UP‐Net to properly handle segmentation challenges. In addition, we evaluate UP‐Net for decoding distorted quick‐response (QR) codes heavily polluted by noise. Experimental results confirm that UP‐Net outperforms existing QR reader mobile applications, highlighting the UP‐Net ability to handle challenging images. Unlike existing methods focused solely on QR code reading or segmentation, UP‐Net offers a combined solution, efficiently and accurately reading distorted QR codes while performing high‐quality semantic segmentation. These unique characteristics render UP‐Net promising for applications demanding robust image analysis in challenging environments.
Endoscopic resection of a giant irregular leiomyoma in fundus and cardia: A case report
Authors: Li Peng , Tang Guang-Ming , Li Pei-Lin , Zhang Chun , Wang Wei-Qiang 
Published: December 2024

BACKGROUND
Endoscopic resection of giant gastric leiomyomas, particularly in the fundus and cardia regions, is infrequently documented and presents a significant challenge for endoscopic surgery.
CASE SUMMARY
Herein, a case of a 59-year-old woman with a giant gastric leiomyoma was reported. The patient presented to the department of hepatological surgery with a complaint of right upper abdominal pain for one month and worsening for one week. The patient was diagnosed as gastric submucosal tumor (SMT), gallstone, and cholecystitis combined with computed tomography and gastroendoscopy prior to operation. Upon admission, following a multi-disciplinary treatment discussion, it was determined that the patient would undergo a laparoscopic cholecystectomy and endoscopic resection of gastric SMT. It took 3 hours to completely resect the lesion by Endoscopic submucosal excavation and endoscopic full-thickness resection, and about 3 hours to suture the wound and take out the lesion. The lesion, ginger-shaped and measuring 8 cm × 5 cm, led to transient peritonitis post-surgery. With no cardiac complications, the patient was discharged one week after surgery.
CONCLUSION
Endoscopic resection of a giant leiomyoma in the cardiac fundus is feasible and suitable for skilled endoscopists.
Pengaruh Pemberian Bolu Pisang Ambon Terhadap Perubahan Tekanan Darah Penderita Hipertensi Di Wilayah Kerja Puskesmas Soropia Kabupaten KonaweHypertension is when the pressure in blood vessels increases above 120/80 mmHg. Blood pressure goal is less than
Authors: Sabina Riska Adni , Ananda Siti Hadrayanti , Demmalewa Jenni Qlifianty , Abadi Ellyani 
Published: December 2024

Hypertension is when the pressure in blood vessels increases above 120/80 mmHg. Blood pressure goal is less than 130/80 mmHg, and when the pressure is 140/90 mmHg or higher, it called as hypertension. One of non-pharmacology therapies used to lower high blood pressure is giving ambon banana cake to the patients with hypertension at Soropia health centre, Soropia district, Konawe. This is a quantitative study used quasi-experiment of pre test and post test with control group design. The observation was conducted twice-before and after treatment. Population of the study were 19 people who suffered hypertension at Soropia health centre, Soropia district, Konawe. 16 people were chosen by using Slovin formula to obtain representative samples. Then, 16 people were divided into 2 groups (8 People were in control group and others were in intervention group). Result of Wilcoxon test concluded that there’s an effect of non-pharmacology therapy by giving Ambon banana cake on blood pressure changes of patients with hypertension
Positive Focusing is Directly Useful
Authors: Accattoli Beniamino , Wu Jui-Hsuan 
Published: December 2024

Recently, Miller and Wu introduced the positive $\lambda$-calculus, a call-by-value $\lambda$-calculus with sharing obtained by assigning proof terms to the positively polarized focused proofs for minimal intuitionistic logic. The positive $\lambda$-calculus stands out among $\lambda$-calculi with sharing for a compactness property related to the sharing of variables. We show that -- thanks to compactness -- the positive calculus neatly captures the core of useful sharing, a technique for the study of reasonable time cost models.Comment: Paper for the proceedings of MFPS 2024
News Laundering, Paywall, Quality Reporting, and the Copyright Law in the Digital China
Authors: Xu Nairui , Yu Zizheng , Chen Lixiong 
Published: December 2024

“News laundering” (xi gao) is an issue concerned by Chinese professional journalists in recent years. It refers to a series of unauthorized practices in appropriating or plagiarizing the published contents or the ideas presented by professional journalists, which is conducted by social media users including opinion leaders, and portal media, who are not authorized with news reporting licenses. From a legal perspective, it is hard to assert that “news laundering” violates Chinese copyright law, as news is not under the protection of the law and no one could monopolize the “facts”. From journalists’ perspective, this is an act of stealing content from the inside of the digital paywall. This conceptual article, by borrowing the scholarship from media and journalism, and law studies, contemplates the complex mechanism of “news laundering” and its implication for the paywall of legacy media and Chinese media systems, providing new insights into the new research field of news laundering under the Chinese context.
A Feminist Critical Discourse Analysis of French and Turkish Dubbings of “Mona Lisa Smile” Movie
Authors: Taşdan Doğan Tuğçe Elif , Ergüney Merve 
Published: December 2024

This study analyzes the original version, Turkish and French dubbings of the movie Mona Lisa Smile, through the Feminist Critical Discourse Analysis (FCDA) method. The study aims to reveal the potential of the Turkish and French dubs of the movie to reproduce gender stereotypes towards women. The movie was chosen through purposive sampling, one of the non-random sampling methods. The observation-notetaking technique was used as the data collection method.10 examples were determined. These discourses were analysed through the FCDA method by comparing the original version with its French and Turkish dubs on the Netflix platform. Gender-based discourses were seen to be preserved in all examples in the French language. In Turkish dubbing, serious losses occurred in all examples from the perspective of gender roles. This study is the first research evaluating the French and Turkish dubbings of an audiovisual product through FCDA; therefore, it presents authentic data for future studies.