bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does Starting Universal Childcare Earlier Influence Children’s Skill Development?
Authors: Kuehnle Daniel , Oberfichtner Michael 
Published: January 2020

AbstractAs many developed countries enact policies that allow children to begin universal childcare earlier, understanding how starting universal childcare earlier affects children’s cognitive and noncognitive skills is an important policy question. We provide comprehensive evidence on the multidimensional short- and longer-run effects of starting universal childcare earlier using a fuzzy discontinuity in the age at starting childcare in Germany. Combining rich survey and administrative data, we follow one cohort from age 6 to 15 and examine standardized cognitive test scores, noncognitive skill measures, and school track choice in a unified framework. Children who start universal childcare four months earlier around age 3 do not perform differently in terms of standardized cognitive test scores, measures of noncognitive skills, school track choice, or school entrance examinations. We also find no evidence of skill improvements for children with low socioeconomic status, although we provide suggestive evidence that they may benefit from high-quality care. Our estimates refer to children who start childcare before they become legally entitled, for whom the literature would predict low gains to starting childcare earlier. We provide further evidence on this relationship between parental resistance to and children’s potential gains from childcare. Simply allowing children to start universal childcare earlier is hence not sufficient to improve children’s skill development, particularly for children with low socioeconomic status.
The Treatment of Bipolar Depression: Current Status and Future Perspectives
Authors: Jelen Luke A. , Young Allan H. 
Published: January 2020

Abstract
Purpose of Review
This paper aims to review current available treatment options and to consider future directions in the treatment of bipolar depression.

Recent Findings
There are a limited number of established treatments that have demonstrated varied efficacy in acute bipolar depression including modern antipsychotics (quetiapine, lurasidone, olanzapine ± fluoxetine and recently cariprazine) and mood stabilisers (lamotrigine and valproate). Lithium has a role in protecting against depressive relapses and suicide. Alternative and experimental treatments including pramipexole, modafinil/armodafinil, omega-3 fatty acids and thyroxine may be used to augment the treatment of bipolar depression. Ketamine represents a major breakthrough, producing rapid reductions in depressive symptoms even in cases of treatment-resistance, but challenges remain in how best to maintain response and reduce unwanted side effects.

Summary
There remains uncertainty with regard to the relative efficacy and safety of established and experimental treatments for bipolar depression. Further work using consistent, optimal trial designs as well as further investigation into novel compounds and treatment interventions is warranted.
Ancient natural philosophy: A resource for environmental education
Authors: Van Ryn Ann , Burns Edgar 
Published: January 2020

AbstractStudying humankind’s relationship to the earth involves broad and deep questions for students as today’s educators explore changing teaching methods. This article highlights benefits of a multidisciplinary approach to environmental education, drawing upon ancient natural philosophy as a coherent conceptual resource. The Greek philosopher Plotinus is introduced to show the application of ancient natural philosophy across all fields and on all levels of knowledge under a common banner. The significance of ancient natural philosophy is its conception of overall unity. This is the key. Unity is implicit in interrelationships between parts to whole on all levels of existence. From such a perspective, all life forms and other entities in the natural world can be understood as interrelated — just as James Lovelock demonstrated in describing the homeostatic state of natural processes on earth. On a similar reasoning, the diversity in people, societies and places can be appreciated physically and sociologically as belonging to one world. Several studies are cited to explore this overlap between ancient natural philosophy and honouring the connection and dependence of humanity on the fragility of the earth’s ecosystem.
A contribution to the theory of economic development and the demographic transition: fertility reversal under the HIV epidemic
Authors: Gori Luca , Lupi Enrico , Manfredi Piero , Sodini Mauro 
Published: January 2020

AbstractAccording to the conventional theory of the demographic transition, mortality decline has represented the major trigger of fertility decline and sustained economic development. In Sub-Saharan Africa (SSA), the HIV/AIDS epidemic has had a devastating impact on mortality, dramatically reversing the long-term positive trend in life expectancies in high HIV-prevalence countries. Moreover, SSA is experiencing a delayed and slower fertility transition compared to other world regions and there is growing empirical evidence highlighting the potential for a paralysis, or even a reversal, of the fertility transition in countries with severe HIV epidemics. This work builds on a unified growth theory-like general equilibrium model combined with HIV spread, where mortality endogenously feeds back into fertility and education decisions. The model supports the evidence of an HIV-triggered fertility reversal in SSA via the fall in education and human capital investments due to increased adult mortality, which eventually breaks the switch from quantity to quality of children. Fertility reversal is predicted to be more likely to occur in countries experiencing severe HIV epidemics, and its effects may persist even under successful scenarios of HIV control. These results suggest that the alarming possibility of a paralysis in the fertility transition, which so far has aroused little concern among international organizations, e.g., in the last round of UN population projections, should be seriously considered with a view to prioritizing policy interventions.
GLOBAL ACTIONS AND VECTOR -THEORY
Authors: BAK ANTHONY , GARGE ANURADHA S. 
Published: January 2020

Purely algebraic objects like abstract groups, coset spaces, and G-modules do not have a notion of hole as do analytical and topological objects. However, equipping an algebraic object with a global action reveals holes in it and thanks to the homotopy theory of global actions, the holes can be described and quantified much as they are in the homotopy theory of topological spaces. Part I of this article, due to the first author, starts by recalling the notion of a global action and describes in detail the global actions attached to the general linear, elementary, and Steinberg groups. With these examples in mind, we describe the elementary homotopy theory of arbitrary global actions, construct their homotopy groups, and revisit their covering theory. We then equip the set

$Um_{n}(R)$

of all unimodular row vectors of length

$n$

over a ring

$R$

with a global action. Its homotopy groups

$\unicode[STIX]{x1D70B}_{i}(Um_{n}(R)),i\geqslant 0$

are christened the vector

$K$

-theory groups

$K_{i+1}(Um_{n}(R)),i\geqslant 0$

of

$Um_{n}(R)$

. It is known that the homotopy groups

$\unicode[STIX]{x1D70B}_{i}(\text{GL}_{n}(R))$

of the general linear group

$\text{GL}_{n}(R)$

viewed as a global action are the Volodin

$K$

-theory groups

$K_{i+1,n}(R)$

. The main result of Part I is an algebraic construction of the simply connected covering map

$\mathit{StUm}_{n}(R)\rightarrow \mathit{EUm}_{n}(R)$

where

$\mathit{EUm}_{n}(R)$

is the path connected component of the vector

$(1,0,\ldots ,0)\in Um_{n}(R)$

. The result constructs the map as a specific quotient of the simply connected covering map

$St_{n}(R)\rightarrow E_{n}(R)$

of the elementary global action

$E_{n}(R)$

by the Steinberg global action

$St_{n}(R)$

. As expected,

$K_{2}(Um_{n}(R))$

is identified with

$\text{Ker}(\mathit{StUm}_{n}(R)\rightarrow \mathit{EUm}_{n}(R))$

. Part II of the paper provides an exact sequence relating stability for the Volodin

$K$

-theory groups

$K_{1,n}(R)$

and

$K_{2,n}(R)$

to vector

$K$

-theory groups.
An alternative interpretation of the Paleogene turtle Cardichelyon rogerwoodi as a hinged kinosternoid
Authors: Joyce Walter G. , Claude Julien 
Published: January 2020

AbstractCardichelyon rogerwoodi is an enigmatic fossil turtle from the late Paleocene to early Eocene of North America. Previous analyses suggested affiliation with Testudinoidea, in particular the big-headed turtle Platysternon megacephalum, based on the presence of multiple musk-duct foramina and a large head. We here highlight previously undocumented characteristics for this turtle, notably the presence of short costiform processes, a rib-like axillary process, and a posterior plastral hinge. Phylogenetic analysis places Cardichelyon rogerwoodi within Testudinoidea, but the exclusion of testudinoids suggest an affiliation with Dermatemydidae. Using consilience with external data we favor placement within Kinosternoidea. Cardichelyon rogerwoodi is therefore an aberrant, hinged kinosternoid that developed in situ in North America during the Paleocene long before the arrival of testudinoids on this continent in the early Eocene.
KOLMOGOROV STORIES
Authors: Belyaev Yu. K. , Hajiyev Asaf H. 
Published: January 2020

Authors of this paper were educated and have spent many years in Lomonosov Moscow State University (MSU), in the Interfaculty Laboratory of Statistical Methods (ILSM). Prof. Yu. K. Belyaev was student of Kolmogorov, and for several years his deputy in the ILSM, created and led by the great A. N. Kolmogorov. Now Prof. Yuri Belyaev is Emeritus Professor at Umea University (Sweden). Asaf Hajiyev was a PhD student in Kolmogorov's ILSM. In this paper some unusual incidents about the legendary Kolmogorov, and people around him are presented. Some stories were taken from the books and the internet (see references) dedicated to the memory of Kolmogorov; some were told by his students, and some happened with authors of this paper.Men are cruel but Man is kind.– A. N. Kolmogorov
Effects of parental input quality in child heritage language acquisition
Authors: DASKALAKI Evangelia , BLOM Elma , CHONDROGIANNI Vasiliki , PARADIS Johanne 
Published: January 2020

AbstractThis study investigates the role of parental input quality on the acquisition of Greek as a heritage language in Western Canada. Focusing on subject use, we tested four groups of Greek speakers: monolingual children, heritage children, and the parents of each one of those groups. Participants completed an elicited production task designed to elicit subject placement in wide focus and embedded interrogative contexts, where postverbal subjects are preferred/required in the monolingual variety. Results gave rise to two main conclusions: first, the parental input received by heritage children may be qualitatively different from the parental input received by monolingual children, in that it contains a higher rate of deviant preverbal subjects. Second, parental input quality in addition to quantity may affect the outcome of heritage language acquisition, in that children producing a higher rate of preverbal subjects had parents whose Greek input was not only quantitatively reduced, but also richer in preverbal subjects.
Grant Park Music Festival and Music in Chicago's “Front Yard”
Authors: BRUCHER KATHERINE 
Published: January 2020

AbstractChicago's Grant Park Music Festival, a free classical music series, provides a case study for exploring how music festivals contribute to the musical life of cities. Each summer, the Grant Park Music Festival Orchestra and Choir perform dozens of free performances at the Jay Pritzker Pavilion in Millennium Park and in residential neighborhoods. In 1935, James C. Petrillo, head of the Chicago local of the American Federation of Musicians, initiated the festival, then called Grant Park Concerts, to employ musicians during the Great Depression with funds from the federal Works Progress Administration. Changes in the city's cultural policies, its demographics, financial support, and expectations for how the festival serves the community have impacted how it programs its season and seeks audiences. Based on archival research, this article focuses on how the festival as a civic institution creates a listening public invested in particular narratives of Chicago as a dynamic city through programming music in public spaces. Looking at Grant Park Music Festival from contemporary and historical angles provides insight into how changes in aesthetic and social values, funding for the arts, and urban planning shape the way a festival engages with the city.
Music Festivals, Ephemeral Places, and Scenes: Interdependence at Cornerstone Festival
Authors: MALL ANDREW 
Published: January 2020

AbstractCornerstone was an annual four-day-long Christian rock festival in Illinois that ran from 1984 until 2012, first in Chicago's northern suburbs and then on a former farm in the rural western part of the state. Most attendees camped on-site, and many arrived one or two days early when the campgrounds opened before official programming started. Like many contemporary multi-day festivals in relatively rural or remote locations, Cornerstone's festival grounds and campsites functioned as a temporary village. For many attendees, music festivals have supplanted local scenes as loci of face-to-face musical life. Outside Cornerstone, participants’ musical lives might be curbed by family, professional obligations, geographic separateness, or cultural stratification. Inside the festival's physical, social, and cultural spaces, however, a cohesive music scene manifested for a brief time every year. This article examines the production of space and place at Cornerstone. In doing so, it contributes a vital link between scene theory and the growing ethnomusicological literature on festivals.
A paternal hypercaloric diet affects the metabolism and fertility of F1 and F2 Wistar rat generations
Authors: Oshio Leonardo Toshio , Andreazzi Ana Eliza , Lopes Jéssica Ferraz , Sá Jackson Pereira de , Bolotari Mariana , Costa Vinícius Moreira Gonçalves , Guerra Martha de Oliveira , Peters Vera Maria 
Published: January 2020

AbstractIncreased fat and carbohydrate intakes based on the Western diet are important lifestyle modifications that lead to hypercaloric inputs, obesity, and male fertility negative effects. Epigenetic transmission may also predispose descended generations to chronic diseases, such as obesity, type 2 diabetes, behavioral, and reproductive disorders. The present study sought to evaluate the influence of a high-fat-high-sugar (HFHS) diet supplied to Wistar rats from 25 to 90 days of life on reproductive and metabolic parameters in male generations F0, F1, and F2. The standard group received the normocaloric – Nuvilab Quimtia® –3.86 kcal/kg. The hypercaloric diet (HD) group received the HFHS diet – PragSoluções® –4.77 kcal/kg. Body weight, adiposity, F1 and F2 prepubertal age evaluations, oral glucose tolerance test, insulin tolerance test, organ weights, sperm count and morphology assessments, and histometric testicular analyses were performed. The HFHS diet promoted dyslipidemia, higher adiposity, lower relative organ weights, and higher mean kidney weight, decreased mean testicle and parenchyma weights and lower height of seminiferous epithelium (HE) for the F0 generation. F1 and F2 offspring of HD group displayed early preprepubertal development, although did not alter the metabolic parameters. Decreased HE and tubular testicular compartment volumetric density and increased intertubular testicular compartment volumetric density and volume in the F1 generation of HD group were observed. Alterations in histometry of intertubular testicular compartment were also noted. It is concluded that the HFHS experimental model altered only paternal metabolic parameters. However, reproductive parameters of the three generations were affected.
Effects of preterm birth induced with or without exogenous glucocorticoids on the ovine glucose–insulin axis
Authors: Bansal Amita , Alsweiler Jane M. , Oliver Mark H. , Jaquiery Anne , Phua Hui Hui , Dragunow Mike , de Matteo Rob , Harding Jane E. , Bloomfield Frank H. 
Published: January 2020

AbstractAntenatal exogenous glucocorticoids (ANG) are standard management for women at risk of preterm birth but are reputed to impair glucose tolerance in preterm offspring. We compared lambs born preterm (137 days gestation) following labour induced with exogenous glucocorticoids (G-Prem, glucocorticoid-induced preterm group), or with a progesterone synthesis inhibitor (NG-Prem, non-glucocorticoid-induced preterm group), with term-born lambs (Term; 149 days). We assessed glucose tolerance, insulin secretion and sensitivity at 4 and 10 months n = 11–14/group) and pancreatic and hepatic gene and protein expression at 4 weeks post-term (4 weeks; n = 6/group) and 12 months (12 months; n = 12–13/group). NG-Prem had higher plasma glucose concentrations than G-Prem, but not Term, at 4 months (Mean[SEM] mM: NG-Prem = 4.1[0.1]; G-Prem = 3.4[0.1]; Term = 3.7[0.1]; p = 0.003) and 10 months (NG-Prem = 3.9[0.1]; G-Prem = 3.5[0.1]; Term = 3.7[0.1]; p = 0.01). Insulin sensitivity decreased from 4 to 10 months, in NG-Prem but not in Term (Mean[SEM] µmol·ml−1·kg−1·min−1·ng−1, 4 vs. 10 months: NG-Prem = 18.7[2.5] vs. 9.5[1.5], p < 0.01; Term: 12.1[2.8] vs. 10.4[1.5], p = 0.44). At 12 months, β-cell mass in NG-Prem was reduced by 30% vs. G-Prem (p < 0.01) and 75% vs. Term (p < 0.01) and was accompanied by an increased β-cell apoptosis: proliferation ratio at 12 months. At 12 months, pancreatic glucokinase, igf2 and insulin mRNA levels were reduced 21%–71% in NG-Prem vs. G-Prem and 42%–80% vs. Term. Hepatic glut2 mRNA levels in NG-Prem were 250% of those in G-Prem and Term. Thus, induction of preterm birth without exogenous glucocorticoids more adversely affected pancreas and liver than induction with exogenous glucocorticoids. These findings do not support that ANG lead to long-term adverse metabolic effects, but support an effect of preterm birth itself.
Should Judges Make Climate Change Law?
Authors: Burgers Laura 
Published: January 2020

AbstractWhat scholars referred to as a climate change litigation ‘explosion’ in 2015 has today become an established movement which is unlikely to stop in the near future: worldwide, over a thousand lawsuits have been launched regarding responsibility for the dangers of climate change. Since the beginning of this trend in transnational climate litigation scholars have warned that the separation of powers is threatened where judges interfere with the politically hot issue of climate change. This article uses Jürgen Habermas's political theory on deliberative democracy to reconstruct the tension between law and politics generated by these lawsuits. This reconstruction affords a better understanding of the implications of climate change litigation: while the role of the judiciary as such remains unchanged, the trend is likely to influence the democratic legitimacy of judicial lawmaking on climate change, as it indicates an increasing realization that a sound environment is a constitutional value and is therefore a prerequisite for democracy.
Trace Element and Isotopic Characteristics of Plagioclase Megacrysts in Plagioclase Ultraphyric Basalts (PUB)
Authors: Nielsen Roger L. , Ustunisik Gokce , Lange Amy E. , Tepley Frank J. , Kent Adam J. R. 
Published: January 2020

AbstractMajor, trace, and isotopic compositions of plagioclase megacrysts from plagioclase ultraphyric basalts (PUB) from multiple mid‐ocean ridges were determined to characterize the liquid compositions from which they were derived. Large (up to 2 cm) plagioclase megacrysts exhibit homogeneous major element compositions, with variable degrees of trace element and isotopic heterogeneity. The pattern and degree of heterogeneity is itself variable between megacrysts, with some being homogenous and others exhibiting a wide range of trace element and isotopic zoning. Liquids calculated to be in equilibrium with the plagioclase megacrysts exhibit a range equivalent to lavas erupted from entire ridge segments. Many of the megacrysts may be considered to be cognate xenocrysts in that they are related to the same mantle material as the host lavas in which they were carried to the surface. The observed trace element patterns together with the isotopic diversity suggest a complex set of processes are active, that include mixing of distinct primitive melts, fractional crystallization, and diffusive reequilibration. The degree to which each process influences the megacrysts varies between individual crystals in each sample. Equally important is the range of composition we see within individual crystals. For example, Ba concentrations vary by as much as a factor of 5 but not systematically from core to rim.
Biofilm formation displays intrinsic offensive and defensive features of Bacillus cereus
Authors: Caro-Astorga Joaquín , Frenzel Elrike , Perkins James R. , Álvarez-Mena Ana , de Vicente Antonio , Ranea Juan A. G. , Kuipers Oscar P. , Romero Diego 
Published: January 2020

AbstractBiofilm formation is a strategy of many bacterial species to adapt to a variety of stresses and has become a part of infections, contaminations, or beneficial interactions. In this study, we demonstrate that profound physiological changes permit Bacillus cereus to switch from a floating to a sessile lifestyle, to undergo further maturation of the biofilm and to differentiate into the offensive or defensive features. We report that floating and biofilm cells are populations that differentiate metabolically, with members of each subpopulation developing different branches of certain metabolic pathways. Secondly, biofilm populations rearrange nucleotides, sugars, amino acids, and energy metabolism. Thirdly, this metabolic rearrangement coexists with: the synthesis of the extracellular matrix, sporulation, reinforcement of the cell wall, activation of the ROS detoxification machinery and production of secondary metabolites. This strategy contributes to defend biofilm cells from competitors. However, floating cells maintain a fermentative metabolic status that ensures a higher aggressiveness against hosts, evidenced by the production of toxins. The maintenance of the two distinct subpopulations is an effective strategy to face different environmental conditions found in the life styles of B. cereus.
Reference data on in vitro anatomy and indentation response of tissue layers of musculoskeletal extremities
Authors: Schimmoeller Tyler , Neumann Erica E. , Owings Tammy M. , Nagle Tara F. , Colbrunn Robb W. , Landis Benjamin , Jelovsek J. Eric , Hing Tod , Ku Joy P. , Erdemir Ahmet 
Published: January 2020

AbstractThe skin, fat, and muscle of the musculoskeletal system provide essential support and protection to the human body. The interaction between individual layers and their composite structure dictate the body’s response during mechanical loading of extremity surfaces. Quantifying such interactions may improve surgical outcomes by enhancing surgical simulations with lifelike tissue characteristics. Recently, a comprehensive tissue thickness and anthropometric database of in vivo extremities was acquired using a load sensing instrumented ultrasound to enhance the fidelity of advancing surgical simulations. However detailed anatomy of tissue layers of musculoskeletal extremities was not captured. This study aims to supplement that database with an enhanced dataset of in vitro specimens that includes ultrasound imaging supported by motion tracking of the ultrasound probe and two additional full field imaging modalities (magnetic resonance and computed tomography). The additional imaging datasets can be used in conjunction with the ultrasound/force data for more comprehensive modeling of soft tissue mechanics. Researchers can also use the image modalities in isolation if anatomy of legs and arms is needed.