bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinación de oferta de suelo urbano disponible para renovación densificada: propuesta metodológica
Authors: Moreno Alba Daniel , Figueroa Monsalve Óscar 
Published: May 2020

La densificación y renovación en el desarrollo urbano, aparecen como la oportunidad para aprovechar las infraestructuras existentes al igual que dar más cabida de población sin necesidad de establecer límites urbanos cada vez mayores. No obstante, la determinación de aquellos predios o espacios en los que se podría densificar, varía de acuerdo a diversos factores, como por ejemplo el contexto normativo o el costo que significa la demolición de construcciones previas. La identificación de estos factores, al igual que el análisis territorial que conllevan, permite conocer qué zonas o terrenos son aptos para la densificación y renovación urbana. Por lo tanto, el propósito principal de esta propuesta, es dar a conocer una metodología para la determinación de suelo urbano disponible. Los objetivos complementarios abordan inicialmente los procesos de crecimiento urbano, tanto por extensión como por densificación, así como su justificación y propuestas de criterios básicos para una densificación integral.
The densification and renewal of urban development appear as the opportunity to take advantage of existing infrastructures as well as to give more population capacity without the need to establish ever greater urban limits. However, the determination of those properties or spaces in which it could be densified varies according to different factors, such as, for example, the regulatory context or the cost of demolishing previous constructions. The identification of these factors, as well as the territorial analysis they entail, makes it possible to know which areas or lands are suitable for densification and urban renewal. Therefore, the main purpose of this proposal is to present a methodology for the determination of available urban land. The complementary objectives initially address urban growth processes, both by extension and by densification, as well as their justification and proposals for basic criteria for an integral densification.
Mapeando la metrópolis fragmentada: cartografías de la segregación residencial socioeconómica en el área metropolitana de Córdoba, Argentina
Authors: Boccolini Sara María 
Published: May 2020

Se mapeó la segregación residencial socioeconómica determinando la desviación estándar del nivel socio económico de los hogares en cada radio censal con respecto a la media provincial. El nivel socioeconómico se determinó con la suma ponderada de cuatro indicadores sociodemográficos del Censo Nacional 2010, procesados con QGIS. Los resultados mostraron que la mayor segregación está en áreas pericentrales y periféricas de los aglomerados urbanos, mientras que en áreas periurbanas es baja o nula. Además, los sectores más segregados en el área metropolitana son los de nivel socioeconómico alto y muy alto. Finalmente, se discutió sobre las implicancias en cuanto al acceso (o no) a espacios de mejor calidad ambiental y urbana, y lo que esto implica para dificultar el acceso a mejor calidad de vida de los grupos vulnerables.
We mapped socioeconomic residential segregation by determining the standard deviation of households’ socio-economic level in each census radius with respect to the provincial average. We determined the socioeconomic level with the weighted sum of 2010 National Census’ four sociodemographic indicators, processed with QGIS. We concluded that the greatest segregation occurs in pericentral and peripheral areas of urban agglomerations, while in peri-urban areas it is low or null. In addition, the greatest segregation in the metropolitan area is that of groups of high and very high socioeconomic status. Finally, we discussed the implications for access (or the lack of) to spaces of better environmental and urban quality, and what this implies to hinder access to better quality of life for vulnerable groups.
Etnodesenhografia: a subjetividade em cadernos de desenho de rua
Authors: Pacheco Pereira Carla Freitas 
Published: May 2020

O artigo trata de uma investigação etnográfica do movimento denominado Urban Sketching. Propõe-se construir um olhar transdisciplinar para fenômenos urbanos contemporâneos, contrapondo a experiência do desenho de rua aos métodos tradicionais. O problema colocado é o deslocamento do modelo de ensino frente aos atuais meios de representação gráfica do espaço. A análise apoia-se na fenomenologia de Merleau-Ponty, na genealogia de Foucault e Certeau, somados a historiografia feminista de Silvia Federici. Baseia-se, também,na etnografia urbana do antropólogo, José Guilherme Magnani, somados à visão da filósofa Ondina Pereira sobre a construção da subjetividade na contemporaneidade. A pesquisa pretende, assim, subsidiar uma visão epistemológica do ensino do desenho contemporâneo nas escolas de Arquitetura e Urbanismo. Analisando a construção da subjetividade a partir do uso da linguagem gráfica, espera-se, por fim, avaliar como o desenvolvimento desta habilidade afeta a percepção do espaço urbano.
The article deals with an ethnographic investigation of the movement called Urban Sketching. It proposes a transdisciplinary cover for the contemporary urban phenomena, contrasting experience of street design to the classics. The problem is the displacement of the model from the forward direction to the means of graphical representation of space. An analysis is based on the phenomenology of Merleau-Ponty, on the genealogy of Foucault and Certeau, in addition to the feminist historiography of Silvia Federici. It is also based on the urban ethnography of the anthropologist, José Guilherme Magnani, added to the vision of the philosopher Ondina Pereira on a work of subjectivity in the contemporary world. The research intends, therefore, to subsidize an epistemological vision of the teaching of children in the schools of Architecture and Urbanism. Analyzing a basic language based on the use of graphic language, it is hoped, finally, to evaluate how the development of this ability affects the perception of the urban space.
La ciudad como dispositivo de modernidad en la cuenca del caribe (1850-1930): trayectorias paralelas en procesos urbanos de La Habana y Barranquilla
Authors: Dede-Acosta Harold 
Published: May 2020

El antes mar de las Antillas, hoy Caribe, es probablemente el espacio geográfico más opaco de las Américas. No obstante sus continuidades, no es posible concebirlo de manera cohesiva como entidad macro-territorial. Perforado por siglos de influencia de potencias extranjeras,Caribees una reapropiación moderna de uno o muchos espacios de historias e historiografías entrecruzadas. Al centro de esta superposición se encuentra la ciudad Caribe: marginal hasta la desaparición del mercantilismo colonial, la ciudad se redinamiza y encuentra un rol como pivote comercial y punto de entrada de la modernidad en los nuevos estados-nación de América. Procesadores de materia prima, pero también de diversidad, de estéticas e ideologías, las ciudades del Caribe son laboratorios para formas de habitar el espacio que debían reacomodar las necesidades y aspiraciones de un espacio geográfico cuyas determinantessui generis la distanciaban de los otros procesos homólogos en Europa. Este trabajo utiliza las ciudades de La Habana y Barranquilla como probetas para delinear los puntos de partida de una posible modernidad propia del Caribe que desborda afiliaciones político-estatales e ideas como modernidades periféricas o altermodernidades.
The ancient sea of the Antilles (renamed as The Caribbean) is probably the most opaque geographical zone in the Americas. Despite its physical continuities, it is impossible to apprehend this macro-territoriality in a cohesive way. Pierced by centuries of dominion of foreign powers, Caribbean is a modern revindication of one or many spaces of intertwined histories and historiographies. At the core of this trans-territorial milieu lies the city: marginal until the disappearance of colonial mercantilism, the Caribbean city boosts as it finds a role as anchor point and entryway for modernity for early American Nation-Sates. Processors of raw materials as well as of diversity, aesthetics and ideologies, Caribbean cities served as laboratories for new forms of inhabiting space meant to re-accommodate the needs and aspirations of a macro-region whose unique features differed from homologue processes in Europe. This work proposes the cities of Havana and Barranquilla as testing ground to outline the starting point of a possible Caribbean modernity beyond national affiliations or ideas such as peripheric or altermodernities.
La vivienda de interés social, detonador dedesigualdad en México: el caso de los Héroes Tecámac, Estado de México
Authors: García Balderas Guadalupe 
Published: May 2020

En este trabajo se busca demostrar que la metodología oficial para la medición de la pobreza en México, oculta la presencia de ésta en los conjuntos habitacionales de interés social, asimismo, se considera que dadas las características de los conjuntos habitacionales que fueron construidos posteriormente a los cambios a la política de vivienda realizados en 1988,es decir, en el contexto del neoliberalismo, representa un detonador de desigualdad para sus habitantes, quienes enfrentan mayores desventajas respecto al resto de la población que se localiza en zonas con mayor infraestructura o mejor situadas. Por lo anterior, se propone un concepto y una metodología alternativa para la medición de la pobreza y la desigualdad que tenga aplicación en los conjuntos habitacionales de interés social.
This paper seeks to demonstrate that the official methodology for the measurement of poverty in Mexico, hides its presence in the housing complexes of social interest, also, it is considered that given the characteristics of the housing complexes that were subsequently built to the Changes to housing policy made in 1988, that is, in the context of neoliberalism, represents a trigger for inequality for its inhabitants, who face greater disadvantages compared to the rest of the population that is located in areas with greater infrastructure or better located. Therefore, an alternative concept and methodology is proposed for the measurement of poverty and inequality that has application in housing complexes of social interest.
Virginia Woolf: The Translations of "A Room of One's Own" and "Three Guineas" to Construct a Feminine Genealogy
Authors: Colorado Prieto Natalia 
Published: May 2020

En este artículo se lleva a cabo un análisis comparativo de las traducciones al español de los ensayos feministas A Room of One’s Own y Three Guineas de Virginia Woolf, así como un estudio de la correlación entre las ideas feministas de Woolf y la situación de las mujeres españolas en el momento en el que las traducciones fueron publicadas y en la actualidad. El objetivo de este trabajo es determinar hasta qué punto las decisiones de los traductores influyeron en la transmisión del mensaje que pretendía transmitir Woolf, y la conexión entre dichas traducciones y la situación de las mujeres en España en el momento que fueron publicadas. El enfoque de la traducción de Newmark (1988) y Holmes (1988), junto con la teoría de la traducción feminista, forman el marco teórico. Los resultados de este estudio demuestran la relevancia de las ideas feministas de Woolf y el papel esencial de la traducción en la construcción de una genealogía femenina.
Evolução da tutela do meio ambiente nas constituições brasileiras
Authors: Faria Fernandes Eduardo , Saddy André 
Published: May 2020

O presente artigo retrata a evolução da proteção do meio ambiente no ordenamento jurídico constitucional brasileiro. A partir do período colonial, do descobrimento até a proclamação da independência, passando por cada uma das constituições brasileiras até chegar a atual de 1988, a análise histórica da tutela constitucional do meio ambiente é de suma importância para a compreensão dos desafios da efetiva proteção do meio ambiente na atualidade. O presente artigo retrata a evolução da proteção do meio ambiente no ordenamento jurídico constitucional brasileiro. A partir do período colonial, do descobrimento até a proclamação da independência, passando por cada uma das constituições brasileiras até chegar a atual de 1988, a análise histórica da tutela constitucional do meio ambiente é de suma importância para a compreensão dos desafios da efetiva proteção do meio ambiente na atualidade.
Acute effects of air pollution on all-cause mortality: a natural experiment from haze control measures in Chiang Mai Province, Thailand
Authors: Vajanapoom Nitaya , Kooncumchoo Patcharee , Thach Thuan-Quoc 
Published: May 2020

Background
Serious haze episodes have been a seasonal event in Chiang Mai province for more than a decade. In 2008, local government agencies introduced comprehensive measures to control haze and limit its impacts on public health. This study assessed the acute effects of ambient air pollutants on all-cause mortality before and after the introduction of those haze control measures.

Methods
We obtained daily mortality counts and data on mass concentrations of particulate matter <10 micron in aerodynamic diameter (PM10), gaseous pollutants (SO2, NO2, O3, and CO), and meteorology in Chiang Mai Province between January 2002 and December 2016. We analyzed the data using a case-crossover approach adjusting for temperature, relative humidity, seasonality, and day-of-week. We assessed change in the excess risks of all-cause mortality associated with an increase in interquartile range (IQR) of pollutant concentration before and after control measures came into force.

Results
We found decreased PM10 levels and markedly reduced excess risks of daily mortality associated with an IQR increase in PM10 concentrations in the years after haze-control measures were implemented (2009–2016). We found mixed results for gaseous pollutants: SO2 showed no significant change in excess risk of daily mortality throughout the study period, while NO2 and CO showed significant excess risks only in the period 2012–2016, and 8-h maximum O3 showed a decrease in excess risk despite an increase in its atmospheric levels after the introduction of haze control measures in 2008.

Conclusions
The findings indicate that the government haze control measures first introduced in Chiang Mai province in 2008 have successfully reduced episodic PM10 concentrations, which has led to a decrease in short-term all-cause mortality.
Role of echocardiography in screening for portopulmonary hypertension in liver transplant candidates: a meta-analysis
Authors: Yin Xin , Shao Yueming , Zhang Yu , Gao Hui , Qin Tingting , Wen Xiaoyu , Yang Chen 
Published: May 2020

Objectives
To demonstrate the screening value of echocardiography for portopulmonary hypertension (POPH) in liver transplant candidates.

Design
Systematic review and meta-analysis.

Background
POPH is a complication of end-stage liver disease that adversely affects the outcome of orthotopic liver transplant. There are no specific symptoms in the early stage of POPH. POPH reduce the survival rate of patients with end-stage liver disease specially if they are not diagnosed. Therefore, early detection may improve prognosis. The objective of this study is to explore the screening value of echocardiography on liver transplant candidates for screening of POPH compared to right heart catheterization (RHC).

Method
PubMed, EMBASE and the Cochrane Library were searched by two independent reviewers for potentially eligible studies published up to 30 June 2019 to retrieve data based on per-patient analysis. STATA, Meta-DiSc, and RevMan were applied to perform this meta-analysis.

Results
Our search yielded 1576 studies, of which 11 satisfied the inclusion criteria. The pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR) and area under the summary receiver operating characteristic (SROC) curve (AUC) of echocardiography for POPH were 0.85 (95% CI [0.65–0.94]), 0.83 (95% CI [0.73–0.90]), 4.99 (95% CI [3.03–8.21]), 0.19 (95% CI [0.07–0.46]), and 0.91 (95% CI [0.88–0.93]), respectively. Deeks’ funnel plot did not indicate the existence of publication bias (P = 0.66).

Conclusions
Echocardiography, a noninvasive modality, provides superior screening for POPH, but the diagnosis of POPH still requires RHC. PROSPERO registration number CRD42019144589.
Assessment of Agro-morphological Characters among Complete Panicle Emergence Mutants of Samba Mahsuri (BPT-5204)
Authors: Suneel B. , Gopi P. , Karteek J. , Ershad M. D. , Laha G. S. , Padmakumari A. P. , Sundaram R. M. , Sonti V. Ramesh , Patel H. K. , Sudhakar P. , Satya A. Krishna , Madhav M. S. 
Published: May 2020

Aims: The aim of the present work was to generate complete panicle emergence mutants of Samba Mahsuri (BPT-5204), using the chemical mutagen, ethyl methane sulphonate (EMS)
Place and Duration of Study: The field evaluation was carried out repeatedly in two locations at Indian Institute of Rice Research, Rajendranagar and at ICRISAT Patancheru Hyderabad. The duration of the study was three successive seasons in triplicates namely, june-2014, january-2015 and june-2015.
Methodology: Seedlings of 28-30 days old were transplanted in 5 lines (each line containing 20 plants) into the field. The plant spacing was 20 cm by 15 cm with density of one hill. The field was irrigated throughout the experiment with average of 10 cm water above the soil level. Regular hand weeding was embarked upon to free the plant of inter specific competition. The phenotypic data was recorded for CPE mutants through visual assessment. The characteristics that required measurements were done according to the usual procedure. The Distinctness, Uniformity and stability of the CPE mutant lines have been recorded following (DUS) test guidelines by UPOV guidelines for rice (38) & Yoshida S (44).
Results: The identified stabilized thirteen complete panicle emergence (CPE) mutants showed superior agro morphological characters, compared with wild type (BPT-5204). The mutants CPE-2 and CPE-3 took 100 days to flowering and CPE-4 and CPE-7 mutants showed superiority for panicle length, and CPE-5 exhibited good performance for grain yield. In correlation analysis CPE trait had a significantly positive correlation with PH and TGW and negative correlation with 50%DFF. The CPE mutants used in the present study exhibited variability for most of the studied traits. Significant variation was detected in the identified stabilized CPE mutants for plant height, panicle length, flag leaf length and width, 50% flowering, different grain types and 1000 grain weight.
Conclusion: The present study discovered adequate genetic divergence in the thirteen stabilized CPE mutants for various qualitative and quantitative traits. The promising mutants identified during the current study have the potential to be used in future breeding programs for getting productive and quality results.
Conditioning Electrical Stimulation Accelerates Regeneration in Nerve Transfers
Authors: Senger Jenna‐Lynn B. , Rabey Karyne N. , Morhart Michael J. , Chan K. Ming , Webber Christine A. 
Published: May 2020

ObjectiveCompared to the upper limb, lower limb distal nerve transfer (DNT) outcomes are poor, likely due to the longer length of regeneration required. DNT surgery to treat foot drop entails rerouting a tibial nerve branch to the denervated common fibular nerve stump to reinnervate the tibialis anterior muscle for ankle dorsiflexion. Conditioning electrical stimulation (CES) prior to nerve repair surgery accelerates nerve regeneration and promotes sensorimotor recovery. We hypothesize that CES prior to DNT will promote nerve regeneration to restore ankle dorsiflexion.MethodsOne week following common fibular nerve crush, CES was delivered to the tibial nerve in half the animals, and at 2 weeks, all animals received a DNT. To investigate the effects of CES on nerve regeneration, a series of kinetic, kinematic, skilled locomotion, electrophysiologic, and immunohistochemical outcomes were assessed. The effects of CES on the nerve were investigated.ResultsCES‐treated animals had significantly accelerated nerve regeneration (p < 0.001), increased walking speed, and improved skilled locomotion. The injured limb had greater vertical peak forces, with improved duty factor, near‐complete recovery of braking, propulsive forces, and dorsiflexion (p < 0.01). Reinnervation of the tibialis anterior muscle was confirmed with nerve conduction studies and immunohistochemical analysis of the neuromuscular junction. Immunohistochemistry demonstrated that CES does not induce Wallerian degeneration, nor does it cause macrophage infiltration of the distal tibial nerve.InterpretationTibial nerve CES prior to DNT significantly improved functional recovery of the common fibular nerve and its muscle targets without inducing injury to the donor nerve. ANN NEUROL 2020;88:363–374.
Computational investigations on the dynamic binding effect of molecular tweezer CLR01 toward intrinsically disordered HIV‐1 Nef
Authors: Bhattarai Anil , Emerson Isaac Arnold 
Published: May 2020

AbstractIntrinsically disordered proteins (IDPs) are highly flexible molecules that undergo disorder to order transition through their interaction with other molecules. IDPs play a vital role in several biological processes ranging from molecular recognition to several human diseases through the protein–protein interaction. The dynamic flexibility of IDPs and their implications in several human diseases enable these molecules to serve as novel therapeutic targets. However, the challenging task is to develop novel drugs against IDPs because of their lack of stable structures and the nature of high conformational flexibility. In this study, we have calculated the dynamic binding effect of the supramolecular tweezer CLR01 against the intrinsically disordered HIV‐1 Nef by employing molecular docking and dynamics simulation approaches. From docking results, we predicted the strong binding affinity of the tweezer with the target residues of Nef. The docking results were further validated from the molecular dynamics simulation studies confirming the conformational stability of Nef upon tweezer binding. These findings provide useful insights into the development of potent inhibitors for targeting Nef protein functions.
Effectiveness of host cell protein removal using depth filtration with a filter containing diatomaceous earth
Authors: Nejatishahidein Negin , Borujeni Ehsan E. , Roush David J. , Zydney Andrew L. 
Published: May 2020

AbstractThe increased cell density and product titer in biomanufacturing have led to greater use of depth filtration as part of the initial clarification of cell culture fluid, either as a stand‐alone unit operation or after centrifugation. Several recent studies have shown that depth filters can also reduce the concentration of smaller impurities like host cell proteins (HCP) and DNA, decreasing the burden on subsequent chromatographic operations. The objective of this study was to evaluate the HCP removal properties of the Pall PDH4 depth filter media, a model depth filter containing diatomaceous earth, cellulose fibers, and a binder. Experiments were performed with both cell culture fluid (CCF) and a series of model proteins with defined pI, molecular weight, and hydrophobicity chosen to match the range of typical HCP. The location of adsorbed (fluorescently labeled) proteins within the depth filters was determined using confocal scanning laser microscopy. Protein binding was greater for proteins that were positively charged and more hydrophobic, consistent with adsorption to the negatively charged diatomaceous earth. The lowest degree of binding was seen with proteins near their pI, which were poorly removed by this filter. These results provide new mechanistic insights into the factors governing the filter capacity and performance characteristics of depth filters containing diatomaceous earth that are widely used in the clarification of CCF.