bluuebunny/crossref_metadata_2025_split huggingface dataset:
Place du régionalisme social dans le droit transnational du travail
Authors: BLACKETT Adelle 
Published: December 2020

RésuméL'auteure historicise le régionalisme social en tant que réponse – pragmatique et de principe – à l'effondrement du compromis du libéralisme encastré et à l’établissement d'un ordre économique international conçu pour empêcher la gouvernance du social au sein de l’économique à l’échelle transnationale. L'analyse du premier rapport du groupe d'arbitrage sur le chapitre relatif au travail de l'Accord de libre‐échange entre pays d'Amérique centrale, États‐Unis et République dominicaine (ALEAC‐RD) montre qu'il faut mettre en avant le régionalisme social afin d'axer l'interprétation des traités de libre‐échange sur des objectifs communs et, au‐delà, de promouvoir les mécanismes de redistribution et la solidarité internationale au sein même des accords commerciaux.
Futuros transnacionales del derecho internacional del trabajo. Introducción
Authors: BLACKETT Adelle 
Published: December 2020

ResumenSe sitúa aquí el número monográfico 2020‐4 de la RIT, sobre los futuros transnacionales del derecho internacional del trabajo, en el contexto del centenario de la OIT y del reto de lograr el objetivo del trabajo decente en un nuevo siglo y bajo presiones transnacionales específicas. La autora sostiene que el derecho internacional del trabajo, como núcleo normativo del derecho transnacional del trabajo, puede desempeñar un papel crucial para ayudar a los múltiples actores involucrados, entre ellos, la OIT en sus funciones normativa y de coordinación, a afrontar el reto y remodelar la arquitectura jurídica transnacional.
How I wonder what you are: Can DNA barcoding identify the larval asteroids of Panama?
Authors: Collin Rachel , Venera‐Pontón Dagoberto E. , Driskell Amy C. , Macdonald Kenneth S. , Boyle Michael J. 
Published: December 2020

AbstractAs part of a project to document the diversity of larval invertebrates on both coasts of Panama, we collected and photographed 141 larval asteroids and sequenced fragments of their mitochondrial cytochrome c oxidase subunit I (COI) and 16S ribosomal DNA. We uncovered 10 Caribbean operational taxonomic units (OTUs) and five Pacific OTUs. We could identify six of the 15 OTUs based on >99% similarity with reference sequences in GenBank: The Pacific species Astropecten verrilli and Pentaceraster cumingi and the Caribbean species Astropecten marginatus, Astropecten antillensis, Oreaster reticulatus, and Mithrodia clavigera. Two other OTUs were placed in BINs in the Barcode of Life Database (BOLD) with unpublished sequences that were identified as Pharia pyramidata from the Pacific and Valvaster striatus, now known from the Caribbean as well as the Indo‐West Pacific. The remaining seven species appear likely to belong to Luidia, as 16S sequences from each have 87%–95% identity with various species of Luidia, and the sequences nest among species of Luidia in neighbor‐joining trees. The low diversity of asteroid larvae reflects ~10% of the diversity of adult sea stars reported from Panama, and highlights the need for broader collection efforts and improved coverage of DNA barcode reference sequences for Luidia and other soft‐bottom species.
The nature and quality of friendship for older adults with an intellectual disability in Ireland
Authors: McCausland Darren , McCallion Philip , Carroll Rachael , McCarron Mary 
Published: December 2020

AbstractBackgroundFriendship is important to quality of life, yet people with intellectual disability have more restricted social networks and fewer friends outside family and support staff.MethodData from a nationally representative longitudinal study of older adults with intellectual disability (aged >40) examined rates and types of friends. Factors associated with having a best friend and friendship quality were explored.ResultsA large majority (92.4%) had friends but just over half (52%) had a best friend. Co‐resident friends (71.8%) were more common than non‐resident friends (62%), while staff friendships (62.5%) were important. The majority of best friends were peers with intellectual disability (63.2%), carer/service providers (15.9%) or family (8.4%). Challenging behaviour and communication difficulty were associated with reduced likelihood of having a best friend. A best friend with intellectual disability was associated with lower friendship quality scores.ConclusionLimited choice and social opportunity may result in a precarious form of friendship for older people with intellectual disability that undermines their quality of life.
The cuffless SOMNOtouch NIBP device shows poor agreement with a validated oscillometric device during 24‐h ambulatory blood pressure monitoring
Authors: Nyvad Jakob , Christensen Kent L. , Buus Niels Henrik , Reinhard Mark 
Published: December 2020

AbstractRepeated cuff‐based blood pressure (BP) measurements may cause discomfort resulting in stress and erroneous recording values. SOMNOtouch NIBP is an alternative cuff‐less BP measurement device that calculates changes in BP based on changes in pulse transit time (PTT) and a software algorithm. The device is calibrated with a single upper arm cuff‐based BP measurement. We tested the device against a validated 24‐h ambulatory BP monitoring (ABPM) device using both the previous (SomBP1) and the current software algorithm (SomBP2). In this study, 51 patients (mean age ± SD 61.5 ± 13.0 years) with essential hypertension underwent simultaneous 24‐h ABPM with the SOMNOtouch NIBP on the left arm and a standard cuff‐based oscillometric device on the right arm (OscBP). We found that mean daytime systolic BP (SBP) with OscBP was 140.8 ± 19.7 compared to 148.0 ± 25.2 (P = .008) and 146.9 ± 26.0 mmHg (P = .034) for SomBP1 and SomBP2, respectively. Nighttime SBP with OscBP was 129.5 ± 21.1 compared with 146.1 ± 25.8 (P < .0001) and 141.1 ± 27.4 mmHg (P = .001) for SomBP1 and SomBP2, respectively. Ninety‐five% limits of agreement between OscBP and SomBP1 were ± 36.6 mmHg for daytime and ± 42.6 mmHg for nighttime SBP, respectively. Agreements were not improved with SomBP2. For SBP, a nocturnal dipping pattern was found in 33% of the study patients when measured with OscBP but only in 2% and 20% with SomBP1 and ‐2, respectively. This study demonstrates that BP values obtained with the cuff‐less PTT‐based SOMNOtouch device should be interpreted with caution as these may differ substantially from what would be obtained from a validated cuff‐based BP device.
Modulation of hepatic miRNA expression in Atlantic salmon (Salmo salar) by family background and dietary fatty acid composition
Authors: Østbye Tone‐Kari K. , Woldemariam Nardos T. , Lundberg Camilla E. , Berge Gerd M. , Ruyter Bente , Andreassen Rune 
Published: December 2020

AbstractThis study finds significant differences in hepatic fatty acid composition between four groups of Atlantic salmon (Salmo salar) consisting of offspring from families selected for high and low capacities to express the delta 6 desaturase isomer b and fed diets with 10% or 75% fish oil. The results demonstrated that hepatic lipid metabolism was affected by experimental conditions (diet/family). The fatty acid composition in the four groups mirrored the differences in dietary composition, but it was also associated with the family groups. Small RNA sequencing followed by RT‐qPCR identified 12 differentially expressed microRNAs (DE miRNAs), with expression associated with family groups (miR‐146 family members, miR‐200b, miR‐214, miR‐221, miR‐125, miR‐135, miR‐137, miR_nov_1), diets (miR‐203, miR‐462) or both conditions. All the conserved DE miRNAs have been reported as associated with lipid metabolism in other vertebrates. In silico predictions revealed 37 lipid metabolism pathway genes, including desaturases, transcription factors and key enzymes in the synthesis pathways as putative targets (e.g., srebp‐1 and 2, Δ6fad_b and c, hmdh, elovl4 and 5b, cdc42). RT‐qPCR analysis of selected target genes showed expression changes that were associated with diet and with family groups (d5fad, d6fad_a, srebp‐1). There was a reciprocal difference in the abundance of ssa‐miR‐203a‐3p and srebp‐1 in one group comparison, whereas other predicted targets did not reveal any evidence of being negatively regulated by degradation. More experimental studies are needed to validate and fully understand the predicted interactions and how the DE miRNAs may participate in the regulation of hepatic lipid metabolism.
Flood susceptibility mapping and assessment using a novel deep learning model combining multilayer perceptron and autoencoder neural networks
Authors: Ahmadlou Mohammad , Al‐Fugara A'kif , Al‐Shabeeb Abdel Rahman , Arora Aman , Al‐Adamat Rida , Pham Quoc Bao , Al‐Ansari Nadhir , Linh Nguyen Thi Thuy , Sajedi Hedieh 
Published: December 2020

AbstractFloods are one of the most destructive natural disasters causing financial damages and casualties every year worldwide. Recently, the combination of data‐driven techniques with remote sensing (RS) and geographical information systems (GIS) has been widely used by researchers for flood susceptibility mapping. This study presents a novel hybrid model combining the multilayer perceptron (MLP) and autoencoder models to produce the susceptibility maps for two study areas located in Iran and India. For two cases, nine, and twelve factors were considered as the predictor variables for flood susceptibility mapping, respectively. The prediction capability of the proposed hybrid model was compared with that of the traditional MLP model through the area under the receiver operating characteristic (AUROC) criterion. The AUROC curve for the MLP and autoencoder‐MLP models were, respectively, 75 and 90, 74 and 93% in the training phase and 60 and 91, 81 and 97% in the testing phase, for Iran and India cases, respectively. The results suggested that the hybrid autoencoder‐MLP model outperformed the MLP model and, therefore, can be used as a powerful model in other studies for flood susceptibility mapping.
Food safety lessons learned from the COVID‐19 pandemic
Authors: Lacombe Alison , Quintela Irwin , Liao Yen‐te , Wu Vivian C. H. 
Published: December 2020

AbstractThe COVID‐19 pandemic has ushered in a new era of food safety. To date, there is no evidence to suggest that consuming food is associated with COVID‐19. Nevertheless, COVID‐19's impact on food safety and security has been grave. The world is currently experiencing several supply chain issues as a direct result of extensive lockdowns and impacts on essential workers' safety. However, disruption in the food supply, while catastrophic in nature, has created opportunities for the advancement of medical science, data processing, security monitoring, foodborne pathogen detection, and food safety technology. This article will discuss the key components for food safety during the COVID‐19 pandemic. The discussion will draw from lessons learned early in the outbreak and will analyze the etiology of the disease through a food safety perspective. From there, we will discuss personal protective equipment, detection of SARS‐CoV‐2, useful surrogates to study SARS‐CoV‐2, and the expanding field of data science, from the food safety point of view. In the future, scientists can apply the knowledge to the containment of COVID‐19 and eventually to future pandemics.
Team‐based learning in nursing education: A scoping review
Authors: Considine Julie , Berry Debra , Allen Joshua , Hewitt Nicky , Oldland Elizabeth , Sprogis Stephanie K. , Currey Judy 
Published: December 2020

AbstractAims and objectivesTo explore the use and student outcomes of Team‐Based Learning in nursing education.BackgroundTeam‐Based Learning is a highly structured, evidence‐based, student‐centred learning strategy that enhances student engagement and facilitates deep learning in a variety of disciplines including nursing. However, the breadth of Team‐Based Learning application in nursing education and relevant outcomes are not currently well understood.DesignA scoping review of international, peer‐reviewed research studies was undertaken according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses extension for scoping reviews.MethodsThe following databases were searched on 7 May 2020: Cumulative Index of Nursing and Allied Health Literature, MEDLINE Complete, PsycINFO and Education Resources Information Center. Search terms related to nursing, education and Team‐Based Learning. Original research studies, published in English, and reporting on student outcomes from Team‐Based Learning in nursing education programmes were included.ResultsOf the 1081 potentially relevant citations, 41 studies from undergraduate (n = 29), postgraduate (n = 4) and hospital (n = 8) settings were included. The most commonly reported student outcomes were knowledge or academic performance (n = 21); student experience, satisfaction or perceptions of Team‐Based Learning (n = 20); student engagement with behaviours or attitudes towards Team‐Based Learning (n = 12); and effect of Team‐Based Learning on teamwork, team performance or collective efficacy (n = 6). Only three studies reported clinical outcomes.ConclusionsOver the last decade, there has been a growing body of knowledge related to the use of Team‐Based Learning in nursing education. The major gaps identified in this scoping review were the lack of randomised controlled trials and the dearth of studies of Team‐Based Learning in postgraduate and hospital contexts.Relevance to clinical practiceThis scoping review provides a comprehensive understanding of the use and student outcomes of Team‐Based Learning in nursing education and highlights the breadth of application of Team‐Based Learning and variability in the outcomes reported.
Angle's Classification–A Prosthodontic Consideration: Best Evidence Consensus Statement
Authors: Campbell Stephen , Goldstein Gary 
Published: December 2020

AbstractPurposeThis Best Evidence Consensus Statement evaluated the existing Angle's classification clinical literature to determine if the Angle's classification as historically determined in maximum intercuspal position (MIP) with hand held casts is coincident with the centric occlusion (CO) determined Angle's classification. In addition, it explored the value of using Angle's classification for edentulous patientsMaterials and methodsThe search strategy was related to the focus questions and limited to Meta‐analyses, Systematic Reviews (SR), Randomized Controlled Trials (RCT) and Clinical Trials. Searches were completed using the term Angle's classification and Boolean Modifiers (AND) with the key terms: dental occlusion, dental occlusion centric, centric occlusion, centric relation, maximal intercuspation, MIP, intercuspal position, and edentulous patient, retrognathia, determination, and prognathia. Additional related articles were culled from the reference lists in the articles found in the PubMed searches.ResultsThe search identified 494 articles related to the selected terminology. Titles were reviewed and selected if related to the focus questions for further review. Seven papers could be identified that addressed the specifics of the questions.ConclusionsThere is evidence that the Angle's classification for many patients will change when recorded in CO compared to the historical MIP determination/definition. A different Angle's classification recorded in CO is potentially a significant diagnostic finding for patients needing complete mouth rehabilitation. The current definitions of Angle's Classification are not useful in the management of edentulous patients.
Neurobehavioural functions during variable and stable short sleep schedules
Authors: Koa Tiffany B. , Lo June C. 
Published: December 2020

AbstractWe investigated whether variable sleep schedules might mitigate the neurobehavioural deficits induced by multiple nights of sleep restriction. In this 4‐night experiment, 78 young adults (age: 18–28 years) were randomly assigned to four groups: 8888, 8666, 8846 and 8486, where each digit corresponded to time‐in‐bed in hours for each study night. After one baseline night of 8‐hr time‐in‐bed, time‐in‐bed remained unchanged for the 8888 group, while the other groups had short sleep schedules (total time‐in‐bed = 18 hr) that differed in the number of time‐in‐bed changes. Sleep was monitored using actigraphy at home. Daytime neurobehavioural functions were assessed in the laboratory at single time points, after the baseline night, and again after 3 nights of the sleep manipulation period. For sustained attention, the 8888 group responded faster in the Psychomotor Vigilance Task after the manipulation period (p = .01), while responses became slower for the less variable sleep schedules (8666 and 8846; p < .01), but not the most variable sleep schedule (8486; p = .14). Processing speed also improved in the 8888 group and the variable 8846 and 8486 groups (p < .01), but not in the stable 8666 group (p = .09). Furthermore, subjective sleepiness was preserved in the 8888 and, importantly, 8486 groups (p > .05), but was elevated in the 8666 and 8846 groups (p < .05). These findings suggest that when sleep opportunities are limited across multiple nights, a variable sleep schedule that allows for prophylactic and/or recovery sleep on some nights may mitigate some daytime neurobehavioural deficits as compared with a schedule with no opportunity for recovery.
Detection of maple toxins in mare's milk
Authors: Sander Johannes , Terhardt Michael , Janzen Nils 
Published: December 2020

AbstractBackgroundPlants from the Sapindaceae family that are consumed by horses (maple) and humans (ackee and litchi) are known to contain the toxins hypoglycin A and methylenecyclopropylglycine which cause seasonally occurring myopathy in horses and entero‐encephalopathic sickness in humans. Vertical transmission of these toxins from a mare to her foal has been described once. However the mare's milk was not available for analysis in this case. We investigated mare's milk in a similar case.ObjectiveWe hypothesized that hypoglycin A and methylenecyclopropylglycine, like other amino acids' are secreted into the milk.AnimalsMare with atypical myopathy.MethodsA sample of the mare's milk and 6 commercial horse milk samples were extracted with a methanolic standard solution and analyzed for hypoglycin A, methylenecyclopropylglycine, and metabolites using tandem mass spectrometry after column chromatographic separation.ResultsThere were hypoglycin A (0.4 μg/L) and the associated metabolites methylenecyclopropylacetyl glycine and carnitine (18.5 and 24.6 μg/L) plus increased concentrations of several acylcarnitines in the milk. The milk also contained methylenecyclopropylformyl glycine and carnitine (0.8 and 60 μg/L). The latter substances were also detected in 1 of 6 commercial horse milk samples.Conclusions and Clinical ImportanceTransmission of the maple toxins can occur through mare's milk. Vertical transmission of Sapindacea toxins might also have importance for human medicine, for example, after consumption of ackee or litchi.
Protein homeostasis in LGMDR9 (LGMD2I) – The role of ubiquitin–proteasome and autophagy–lysosomal system
Authors: Franekova Veronika , Storjord Hilde I. , Leivseth Gunnar , Nilssen Øivind 
Published: December 2020

AbstractAimsLimb‐girdle muscular dystrophy R9 (LGMDR9) is an autosomal recessive disorder caused by mutations in the fukutin‐related protein gene (FKRP), encoding a glycosyltransferase involved in α‐dystroglycan modification. Muscle atrophy, a significant feature of LGMDR9, occurs by a change in the normal balance between protein synthesis and protein degradation. The ubiquitin–proteasome system (UPS) and autophagy–lysosomal system play a key role in protein degradation in skeletal muscle cells, but their involvement in the pathology of LGMDR9 is still largely unknown. We have aimed at clarifying whether proteolysis through the UPS and the autophagy–lysosomal pathway is dysregulated in LGMDR9 patients.MethodsVastus lateralis biopsies from 8 normal controls and 12 LGMDR9 patients harbouring the c.826C>A/c.826C>A FKRP genotype were assessed for protein markers related to UPS, the autophagy–lysosomal system and endoplasmic reticulum (ER) stress/unfolded protein response (UPR), followed by ultrastructural analysis by transmission electron microscopy (TEM).ResultsProtein levels of E3 ubiquitin ligases Atrogin‐1 and MuRF1 showed a pattern similar to normal controls. Elevation of the autophagy markers Atg7, LC3B‐II, decreased level of p62 as well as downregulation of the negative autophagy regulator mTORC1, indicated an activation of autophagy in LGMDR9. Mitophagy markers Bnip3 and Parkin were decreased. TEM analysis demonstrated accumulation of autophagosome‐like structures in LGMDR9 muscle. There was also an increase in the expression of ER stress/UPR markers PDI, peIF2α and CHOP and a decrease in IRE1α. However, GRP94, Bip and Calnexin remained unchanged.ConclusionOur findings indicate that autophagy and ER stress are induced in LGMDR9 muscle.
Do Fed Forecast Errors Matter?*
Authors: Tien Pao‐Lin , Sinclair Tara M. , Gamber Edward N. 
Published: December 2020

AbstractIn order to make forward‐looking policy decisions, the Fed relies on imperfect forecasts of future macroeconomic conditions. If the Fed’s forecasts are rational, then the difference between the actual outcome and the Fed’s forecast is exogenous to the information set of the Fed at the time the forecast was produced. We investigate the effect of the Fed’s forecast errors on output and price movements under the assumption that the Fed intends to implement policy through a forward‐looking Taylor rule with perfect foresight. Our results suggest that although the mean absolute magnitude of the Fed’s forecast errors is large, the impact on the macroeconomy is reassuringly small, although the impact is larger when we take into consideration the Fed’s inability to forecast recessions.
The treatment of binge eating disorder with cognitive behavior therapy and other therapies: An overview and clinical considerations
Authors: Q da Luz Felipe , Hay Phillipa , Wisniewski Lucene , Cordás Táki , Sainsbury Amanda 
Published: December 2020

SummaryBinge eating disorder (BED) is a public health problem in several countries. BED is commonly associated with comorbidities such as obesity, diabetes, and depression. Notwithstanding the health problems associated with BED, evidence‐based treatments for BED are not widely used by healthcare professionals worldwide. Thus, we provide an overview of the leading evidence‐based psychological therapies for BED, with the intention of informing healthcare professionals and the general community and facilitating greater provision of treatment. Cognitive behavior therapy (CBT) for BED is briefly presented, focusing mainly on adaptations and stages of the cognitive behavior therapy‐enhanced (CBT‐E) transdiagnostic model for eating disorders. We also succinctly discuss the use of CBT in combination with weight management interventions or pharmacotherapy, as well as the use of interpersonal therapy and dialectical behavior therapy for BED. We conclude that there is a variety of evidence‐based psychological therapies that can be used by a variety of healthcare professionals (not only by psychologists) to help reduce binge eating and associated psychopathology in people with BED. Given the high and increasing prevalence of BED, as well as the availability of effective evidence‐based treatments, we encourage more healthcare professionals to explore up‐skilling to assist people with BED.