bluuebunny/crossref_metadata_2025_split huggingface dataset:
Moisture Sorption Isotherm and Isosteric Heat of Dried Cabya (Piper retrofractum Vahl) Powder
Authors: Hawa L C , Aini K N N , Maharani D M , Susilo B 
Published: June 2020

Abstract
Cabya (Piper retrofractum Vahl) is a widely utilized herbal plant for Indonesian traditional medicine. Up to date, the commonly applied storage method for this plant is in dried form, and makes it less effective for distribution process and less attractive for consumers preference, i.e. consumers usually prefers to consume herbal product in powdered form. In the attempt to provide an optimized storage condition of dried cabya powder, the study was conducted to analyze the sorption isotherm behavior of dried cabya powder and to obtain the fittest sorption isotherm model by comparing obtained data to five commonly used sorption isotherm models, i.e. BET, Oswin, Smith, Caurie, and GAB model. The sorption isotherm data was obtained using static gravimetric method in 24 h of interval weighing observation. Six saturated salt solution, i.e. KOH, MgCl2, KI, NaCl, KCl, and KNO3 were employed for water activity (aw
) in the range of 0.063 - 0.936. The observation was conducted at three different temperatures, i.e. 25±2°C, 35±2°C, and 45±2°C with triplicates. The results indicated that GAB model satisfactorily describe the sorption isotherms behavior of dried cabya powder. The mathematical form of isosteric heat equation of dried cabya powder in adsorption and desorption were also presented.
Isolation and Characterization of Effective Microorganism from Oil Palm Rhizhopheric Soil and Evaluation of Their Potential as Biofertiliser
Authors: Nor M N M 
Published: June 2020

Abstract
Plant nutrients are vital components of sustainable agriculture. Soil microorganisms play a significant role in regulating dynamics of organic matter decomposition and availability of plant nutrients such as nitrogen (N), phosphate (P) and sulphur (S), as well as stimulating plant growth. Soil microbial inoculants associated with rhizosphere region of plants work as biofertilisers. In this study, beneficial bacteria were isolated from rhizospheric soils collected from an oil palm plantation in Temerloh, Pahang, Malaysia. Rhizospheric soils (n = 6) were sampled from oil palm plants with heavy production of fresh fruit bunches, due to supplementation of biofertiliser. Isolation of bacteria was carried out on soil extract agar using a dilution plate method. Total bacterial count from isolation plates was in the range of 6.0 × 107 to 7.3 × 107 cfu per gram of soil. All bacterial isolates (n = 150) were purified and characterised for production of plant beneficial enzymes and hormones such as indole-3-acetic acid (IAA), siderophore, nitrogenase and phosphatase. Two bacterial isolates that were positive in phosphate solubilising assay, nitrogen fixers and IAA producers assay were identified as Brevibacillus sp., and Burkholderia sp. respectively, based on 16S rRNA gene sequences.
Impact of Gold Mining on Physical Properties of Inceptisols in Muaro Sijunjung, West Sumatra Indonesia
Authors: Yulnafatmawita  , Yasin S , Kurnia E F , Haris Z A 
Published: June 2020

Abstract
Open mining causes some problems to the soil properties both in situ and ex situ or in the environment. A research on the effect of gold mining on physical properties of Inceptisols was conducted in Nagari Muaro, District of Sijunjung West Sumatra Indonesia. The disturbed and undisturbed soil was sampled at the ex gold mining, and at the previous land use, especially rubber plantation and grassland. Parameters analysed were soil texture, bulk density (BD), hydraulic conductivity (HC), soil organic matter (SOM), soil aggregate stability (SAS), and water content. Based on laboratory analyses, it was found that gold mining process changed soil physical properties at the top 0-40 cm soil in Muaro Sijunjung. It decreased SOM content, soil HC, SAS index, TP, and increased soil BD or hardness compared to the previous land use. The soil must be rehabilitated to increase its productivity and to anticipate environmental pollution.
Proximate Composition and Glycaemic Index of Cookies from Corn Flour Mixed Black Soybean
Authors: Triandita N , Putri N E 
Published: June 2020

Abstract
The metabolic characteristics of type 2 diabetes subject are abnormally high concentration of glucose in blood. They need low glycaemic index food to control their bloods glucose. Meals from cereal and bean have important protein, vegetable oils, dietary fibre, and low starch to controlling it. The purpose of this research was to analyzed the proximate composition and glycaemic index of cookies from corn flour and black soybean flour. Proximate composition determined by AOAC methods. The glycaemic index data was measured from nine normal subject (± 23 years) that selected from agricultural student in Garut University. About 50 g glucose was consumed by subjects. Capillary blood samples were taken by glucometer in the fasting state and then at 15, 30, 45, 60, 90, and 120 minutes from the start consumption of glucose. After a week, subjects were consumed of cookies sample equivalent with 50 g glucose. Samples were analyzed for blood glucose concentration and incremental areas under blood glucose curves were calculated. The glycaemic index of cookies was calculated as the incremental area under curve (iAUC) of the cookies expressed as a percentage of the individual’s average incremental area under curve (iAUC) of the glucose. The results showed that the cooky contained moisture (3.79±0.07%), ash (1.07±0.03%), lipid (29.97±0.28%), protein (6.03±0.06%), crude fiber (3.13±0.38%), and carbohydrate (59.15±0.31%). The cookies have 40.00±17.95 glycaemic index and it was classified as low glycaemic food (less than 55). Furthermore, consuming the cookies could be control the blood glucose of subjects.
Increasing Health Benefit of Wild Yam (Dioscorea hispida) Tuber by Red Mold (Angkak) Fermentation
Authors: Estiasih T , Irawati  , Kuliahsari D E , Widayanti V T 
Published: June 2020

Abstract
Detoxification of cyanogen is very important in cyanide containing tubers such as wild yam (Dioscorea hispida). Principally, cyanogen detoxification is by converting cyanogenic glycoside into acetone cyanohydrin and further converted into free HCN that is easily removed by heating or soaking. Conversion of cyanogenic glycoside into free HCN is catalyzed by beta glucosidase enzyme (linamarase) in linamarin deglycosilation and a- hydroxyinitril liase (HNL) in acetone cyanohydrin degradation into free HCN and acetone. Endogen linamarase is found in the tubers and exogenous linamarase might be from microbes. It is supposed that fermentation of wild yam by angkak will reduce cyanide level. Angkak or Red Mold Rice (RMR) is a product of rice fermentation using Monascus sp mainly M. purpureus. Beside red pigment, angkak fermentation also produces a variety of secondary metabolites such as lovastatin, mevinolin, and citrinin. Monacolin K (lovastatin) from Monascus purpureus is an inhibitor for HMG-CoA reductase in cholesterol biosynthesis. Monacolin K production is higher in Dioscorea substrate compared to rice. RMD (Red Mold Dioscorea) reveals higher anti-cholesterol activity and anti-hypertension than red mold rice. RMD also exhibits antioxidant, anti-diabetic, anti-obesity, and induces cancer sell apoptosis and does not reveal mutagenic and toxicity. In RMD, monascin and ankaflavin have a role in reducing cholesterol. It is expected that wild yam fermentation by angkak will reduce cyanide level and produce health beneficial secondary metabolites.
The Effect of Addition Papaya Leaf Extract (Carica papaya L.) on Reducing Caffeine Levels in Robusta Coffee
Authors: Saloko S , Handito D , Murad  , Apriani N 
Published: June 2020

Abstract
The purpose of this study was to determine the effect of adding papaya leaf extract (Carica papaya L.) to a decrease in caffeine content in coffee. This study used a randomized completely block design (RCBD) using one factor, namely the addition factor of papaya leaf extract that consisting of 3 replications. The parameters tested were moisture content, ash content, caffeine content, antioxidant activity and total phenols, physical quality parameters in the form of colour °Hue value and L* value and organoleptic quality in the form of taste and aroma. The effect of adding different papaya leaf extracts had a significant influence on (moisture content, caffeine content, antioxidant activity and total phenol), the colour parameters (L* values) and the organoleptic parameters were (taste scoring methods). Treat the addition of 25% papaya leaf extract was the best treatment in reducing caffeine levels in coffee. The treatment produces coffee with a moisture content 4.87%; caffeine content 0.66%; antioxidant activity 53.33%; total phenol 510.48 mg GAE/g; colour L* 8.48 and taste 4.35 (bitter).
Brewing characterization for optimum functional properties of Dampit Robusta (Coffea canephora) and Liberica (Coffea Liberica) coffee leaves tea
Authors: Fibrianto K , Muliadi B S , Tedja C A , Hartari A , Legowo A M , Al-Baarri A N 
Published: June 2020

Abstract
Coffee leaf is rich of bioactive compound such as phenolic acids, flavonoids, alkaloids, tannin, and caffeine. This study aims to determine optimal brewing conditions for Dampit Robusta and Liberica coffee leaf tea with total phenolic content, tannin content and antioxidant activity as response, also to determine its sensory characteristics. The results suggest that the optimum brewing condition of Dampit Robusta coffee leaves tea was obtained at 95.30°C for 5.14 minutes with total phenolic compound of 468.26 ± 4.16 mg GAE/g, tannin content 303.95 ± 8.17 μg TAE/g, and IC50 antioxidant activity was 14.91 ± 2.48 ppm. Meanwhile the brewing of Dampit liberica coffee tea leaves was optimum at 95.52°C for 6.03 minutes, with the total phenolic content, tannin content, and antioxidant activity were 562.72 ± 20.21 mg GAE/g, 434.86 ± 34.05 μg TAE/g and 12.68 ± 1.89 ppm consecutively. It was also found that Robusta tea leaves have more dominant floral flavour while Liberica tea leaves were dominated by burnt flavour, bitter taste and astringent mouth-feel.
Designing Instant Corn Rice Using the Product Design Phase of Quality Function Deployment
Authors: Hidayat K , Asfan  , Asfan D F , Nursiyam U A 
Published: June 2020

Abstract
Corn rice is one of popular foods in Madura. It refers to main meal consisting of rice grains and grinding corn. Often, it takes long time for preparation; thus, instant product of corn rice is needed. The purpose of this study aims to design Madura instant corn rice products according to consumer preference. Development of product design development involves Quality Function Deployment (QFD) method of the product design phase. The results of this study indicate eleven stages of the process carried out to make instant corn rice products. The product was made as follows: (1) sorting, carried out to select good quality corn, (2) milling, carried out to operate size reduction of the corn, (3) sieving, carried out to produce uniform corn rice faction, and (4) weighing. Washing and soaking of corn was required to remove foreign materials; then followed by steaming, drying 1, boiling, cooling, and drying 2. Ultimately, instant corn rice was packaged. In this regard, boiling process showed importance, with a value of 492,921, then sorting with a value of 454,721, and drying process with a value of 432,446.
Antecedents of Attitude Toward Green Products and its Impact on Purchase Intention
Authors: Lestari E R , Hanifa KPU , Hartawan S 
Published: June 2020

AbstractThe lack of information related to green consumption behaviour becomes an obstacle to both local and international markets in developing their marketing strategy to promote green products. Therefore, it is fundamental to recognize green behaviour of consumers through their purchase intention towards green products, considering that this trend is quite new for them. The purpose of the study is to examine the relationship between three antecedents of attitude towards green products, namely, eco-label, environmental concern and peer pressure, as well as to analyse their influence to consumer’s purchase intention. In this study, the Theory of Reasoned Action (TRA) is used as theoretical research framework. This study investigates the green products, particularly on the ready to drink (RTD) beverage products in a paperboard package certified by Forest Stewardship Council (FSC). The data were collected from 386 respondents in Malang, Indonesia. The findings of this study signified that eco-label, environmental concern and peer pressure have a significant positive impact on the attitudes towards green products. Moreover, this attitude also has a positive impact on green products purchase intention.
Fatigue life investigation of non-load carrying fillet weld of structural offshore steel S460G2+M using experiment and FEM simulation
Authors: Andud D , Saidin S , Manurung Y H P , Faiz Mat M , Salim K , Mahmud A , Dawam A A , Said M K M , Bani S , Jalani S , Zaukah Ibel M , Yasan M Y M , Zainudin D , Abas H 
Published: June 2020

Abstract
This research deals with the fatigue life investigation using experiment and FEM simulation on longitudinal fillet weld of structural offshore steel S460G2+M with a thickness of 10mm. The experimental fatigue test is conducted based on nominal stress (NS) approach while the simulation uses the effective notch stress (ENS) approach for fatigue life assessment. The investigation begins with the preparation of the longitudinal fillet weld fatigue specimen using Milling Machine based on the IIW fatigue specimen design recommendation and joined using the semi-automatic GMAW process following the AWS D1.1 procedure. Fatigue testing on non-load carrying fillet weld is conducted using the Instron Fatigue Machine with a stress ratio of 0.1 with constant amplitude loading and stress loading from 50%-75% of the yield strength of the base material. For the simulation approach, the 3D longitudinal fillet weld geometry is created using CAD based on the ENS design procedures of IIW where the sizes and dimensions are similar to the experimental fatigue specimen. The static elastic stress analysis of the model is conducted using MSC Marc/Mentat FEM software. Based on the IIW fatigue data evaluation, it is found that the natural mean curve of the longitudinal fillet weld obtained 146 MPa of FAT class which exceeds approximately 106% from the IIW FAT class recommendation for a longitudinal fillet joint. However, the characteristic curve of 97.7% failure probability of the parts only attained 95 MPa of FAT class, but still exceeds approximately 33% form the IIW FAT class. In the ENS fatigue assessment of the 3D longitudinal fillet weld, it is found that the model obtained 195MPa of FAT class which is inferior approximately 15 % from the FAT class recommendation of IIW. Also, it is found that both S-N curves of NS after conversion to ENS system have a good agreement with the S-N curve of ENS of 3D longitudinal fillet weld model and the IIW recommendation due to only 16 % and 34% lower as compared with the IIW FAT class recommendation for ENS.
ASHP national survey of pharmacy practice in hospital settings: Prescribing and transcribing—2019
Authors: Pedersen Craig A , Schneider Philip J , Ganio Michael C , Scheckelhoff Douglas J 
Published: June 2020

Abstract

Purpose
Results of the 2019 ASHP national survey of pharmacy practice in hospital settings are presented.

Methods
Pharmacy directors at 4,863 general and children’s medical/surgical hospitals in the United States were surveyed using a mixed-mode method of contact by email and mail. Survey completion was online, using an online survey application. IQVIA supplied data on hospital characteristics; the survey sample was drawn from the IMS Health hospital database.

Results
The response rate was 10.8%. Pharmacists are increasingly managing medication use in the areas of vancomycin therapy, antibiotic selection and dosing, and anticoagulation. Electronic health record (EHR) decision support is guiding prescribing, and nearly 50% of hospitals are customizing drug warnings. Adoption of compounding technology continues, with 43.6% of hospitals using technology in their sterile compounding processes. Nearly half of hospitals have active opioid stewardship programs, and pharmacists are leading these efforts. Specialty pharmacy operations are growing in health systems. Human resource commitments to support new services are increasing; however, vacancy rates for technicians are challenging. Staff credentialing continues to expand for pharmacist and technicians.

Conclusion
Pharmacists continue to assume greater responsibility for writing medication orders, dosing, ordering laboratory tests, and monitoring outcomes. Health-system pharmacists are taking a leading role in addressing the opioid crisis, advancing safety in compounded sterile preparations through adoption of intravenous workflow technologies, and optimizing EHR applications to leverage clinical decision support tools to improve the safe prescribing and use of medications.
Does Class Proportion of Students with Non-Western Origin in High Schools Affect Drinking Habits Among Ethnic Danish Students?
Authors: Hoffmann Sofie H , Pisinger Veronica S C , Norredam Marie , Tolstrup Janne S , Thygesen Lau C 
Published: June 2020

Abstract

Aim
the objective was to test the hypothesis that a higher proportion of students with non-Western origin in high school classes is associated with lower and less frequent alcohol consumption among ethnic Danish students.

Method
data on country of origin was obtained from the Danish Civil Registration System, while information on drinking habits were derived from the Danish National Youth Study 2014. Multilevel zero-inflated binominal regression was used to assess the association between class proportion of students with non-Western origin and odds of non-drinking and mean weekly alcohol consumption, while multilevel logistic regression was used to assess the association with frequent binge drinking.

Results
a higher proportion of students with non-Western origin in class was associated with higher odds of non-drinking among ethnic Danish student in the same class. For example, ethnic Danish boys in classes with more than 15% of the students of non-Western origin had 77% higher odds of being non-drinkers, compared to ethnic Danish boys in classes where 0–5% had non-Western origin (OR: 1.77, 95% CI; 1.42–2.20). Among ethnic Danish students that did consume alcohol, class proportion of students with non-Western origin was not associated with weekly alcohol consumption, while a higher proportion of students with non-Western origin in class was associated with lower odds of frequent binge drinking.

Conclusion
the downward drinking trend among adolescents in Western countries may be partly explained by the higher proportion of youth with non-Western origin, influencing the prevalence of drinking and frequency of binge drinking among adolescents in the ethnic majority population.
A Cohort Study of the Temporal Stability of ImPACT Scores Among NCAA Division I Collegiate Athletes: Clinical Implications of Test–Retest Reliability for Enhancing Student Athlete Safety
Authors: Mason Sara J , Davidson Bradley S , Lehto Marybeth , Ledreux Aurélie , Granholm Ann-Charlotte , Gorgens Kim A 
Published: June 2020

Abstract

Objective
In this study we examined the temporal stability of the Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) within NCAA Division I athletes across various timepoints using an exhaustive series of statistical models.

Methods
Within a cohort design, 48 athletes completed repeated baseline ImPACT assessments at various timepoints. Intraclass correlation coefficients (ICC) were calculated using a two-way mixed effects model with absolute agreement.

Results
Four ImPACT composite scores (Verbal Memory, Visual Memory, Visual Motor Speed, and Reaction Time) demonstrated moderate reliability (ICC = 0.51–0.66) across the span of a typical Division I athlete’s career, which is below previous reliability recommendations (0.90) for measures used in individual decision-making. No evidence of fixed bias was detected within Verbal Memory, Visual Motor Speed, or Reaction Time composite scores, and minimal detectable change values exceeded the limits of agreement.

Conclusions
The demonstrated temporal stability of the ImPACT falls below the published recommendations, and as such, fails to provide robust support for the NCAA’s recommendation to obtain a single preparticipation cognitive baseline for use in sports-related concussion management throughout an athlete’s career. Clinical interpretation guidelines are provided for clinicians who utilize baseline ImPACT scores for later performance comparisons.
Diverse Temporal Dynamics of Repetition Suppression Revealed by Intracranial Recordings in the Human Ventral Temporal Cortex
Authors: Rangarajan Vinitha , Jacques Corentin , Knight Robert T , Weiner Kevin S , Grill-Spector Kalanit 
Published: June 2020

Abstract
Repeated stimulus presentations commonly produce decreased neural responses—a phenomenon known as repetition suppression (RS) or adaptation—in ventral temporal cortex (VTC) of humans and nonhuman primates. However, the temporal features of RS in human VTC are not well understood. To fill this gap in knowledge, we utilized the precise spatial localization and high temporal resolution of electrocorticography (ECoG) from nine human subjects implanted with intracranial electrodes in the VTC. The subjects viewed nonrepeated and repeated images of faces with long-lagged intervals and many intervening stimuli between repeats. We report three main findings: 1) robust RS occurs in VTC for activity in high-frequency broadband (HFB), but not lower-frequency bands; 2) RS of the HFB signal is associated with lower peak magnitude (PM), lower total responses, and earlier peak responses; and 3) RS effects occur early within initial stages of stimulus processing and persist for the entire stimulus duration. We discuss these findings in the context of early and late components of visual perception, as well as theoretical models of repetition suppression.
Coronavirus Disease 2019 (COVID-19) Pharmacologic Treatments for Children: Research Priorities and Approach to Pediatric Studies
Authors: Garcia-Prats Anthony J , Salazar-Austin Nicole , Conway James H , Radtke Kendra , LaCourse Sylvia M , Maleche-Obimbo Elizabeth , Hesseling Anneke C , Savic Rada M , Nachman Sharon 
Published: June 2020

AbstractClinical trials of pharmacologic treatments of coronavirus disease 2019 (COVID-19) are being rapidly designed and implemented in adults. Children are often not considered during development of novel treatments for infectious diseases until very late. Although children appear to have a lower risk compared with adults of severe COVID-19 disease, a substantial number of children globally will benefit from pharmacologic treatments. It will be reasonable to extrapolate efficacy of most treatments from adult trials to children. Pediatric trials should focus on characterizing a treatment’s pharmacokinetics, optimal dose, and safety across the age spectrum. These trials should use an adaptive design to efficiently add or remove arms in what will be a rapidly evolving treatment landscape, and should involve a large number of sites across the globe in a collaborative effort to facilitate efficient implementation. All stakeholders must commit to equitable access to any effective, safe treatment for children everywhere.