bluuebunny/crossref_metadata_2025_split huggingface dataset:
Testes de biocompatibilidade: cultivo de células animais e suas aplicações em estudos de toxicidade
Authors: Heggendorn Fabiano Luiz , Gonçalves Lúcio de Souza , Cardoso Elisama Azevedo , Lutterbach Márcia Teresa Soares , Lione Viviane de Oliveira Freitas 
Published: June 2020

Introdução: o cultivo in vitro de células animais é uma tecnologia moderna, baseada em fundamentos e princípios científicos com inúmeras aplicações, levando inclusive, a união de organizações internacionais no sentido de validar modelos de ensaios in vitro para avaliar toxicidade de produtos químicos, tendo em vista que estes são de baixo custo, maior produtividade e fornece resultados mais rápidos. Objetivo: Abordar por meio de revisão bibliográfica os métodos de avaliação de citotoxicidade mais empregados, além de outros ensaios biológicos necessários para testes de biocompatibilidade. Metodologia: foram selecionados os principais trabalhos e normas por meio de busca nas bases de pesquisa de trabalhos científicos da Scielo, Google Acadêmico e livros sobre o tema, a fim de possibilitar um embasamento para um adequado delineamento de ensaios in vitro de citotocicidade. Resultados: A atual disponibilidade de uma variabilidade de metodologias e linhagens celulares em bancos nacionais e internacionais tornou possível a larga utilização da cultura de células como modelos in vitro para avaliações toxicológicas. Conclusão: testes iniciais de citotoxicidade apresentam limitações quando correlacionados com as situações clínicas, porém são validos para determinar o comportamento biológico dos materiais e/ou seus componentes, estabelecendo informações essenciais na fase inicial de investigação de um biomaterial e direciona os testes in vivo necessários. Além dos ensaios de citotoxicidade, que não devem ser equiparados a biocompatibilidade, a avaliação de um dispositivo médico deve ser baseada em testes in vivo que analisem a toxidade aguda e crônica, inflamação, irritação, sensibilidade, carcinogenicidade e mutagenicidade, reações alérgicas, hemocompatibilidade e toxidade sistêmica.
Síndrome de Seckel: uma revisão sistemática sobre a produção científica nos campos de atuação da saúde
Authors: Passos Ana Tereza Paiva , Brasileiro Ismênia de Carvalho 
Published: June 2020

Introdução: A Síndrome de Seckel é uma doença genética autossômica recessiva, sua incidência se caracteriza por 1:10.000 em recém nascidos vivos. O tratamento destes pacientes é voltado para as deficiências: orofaciais, musculoesqueléticos, cardiológicos, oftalmológicos e mentais, são anormalidades que devem ser acompanhadas por profissionais de cada área. É possível observar a dificuldade em encontrar artigos que falem sobre o assunto, principalmente em áreas como a Fisioterapia. O estudo tem como objetivo facilitar a identificação dos artigos sobre a Síndrome de Seckel pelos profissionais da saúde em suas diversas áreas e incentivar a realização de artigos científicos por aqueles que realizam a intervenção em um indivíduo com a Síndrome. Metodologia: trata-se de uma revisão sistemática, apresentando 23 artigos das diversas áreas da saúde. Discussão: a maioria dos estudos foram publicados nos últimos 3 anos (32%). Os estudos aqui apresentados foram em sua maioria realizados na Índia (30%) e realizados principalmente na área da medicina, 19 (82%) estudos no total. Existem mais 4 (17%) artigos entre as áreas de Odontologia e Fonoaudiologia e apenas uma dissertação na área da Fisioterapia. Conclusão: o estudo reuniu publicações de diversos países e áreas da saúde sobre a Síndrome de Seckel, que se trata de uma anomalia rara. Há uma escassez na literatura que abrange terapêuticas para o quadro clinico apresentado, característico da síndrome.
Construção de tecnologia leve como produto da disciplina segurança do paciente
Authors: Franco Patrícia da Costa , Souza Daniela Sandy Silva de , Sampaio Sara Nogueira , Moraes Bruna de Oliveira , Oliveira Hadelândia Milon de , Pina Rizioléia Marina Pinheiro 
Published: June 2020

Objetivo: Descrever a experiência vivenciada por residentes do primeiro ano do Programa de Enfermagem Obstétrica de uma Universidade pública do Amazonas/Hospital Escola na construção de um Procedimento Operacional Padrão (POP) de identificação do paciente direcionado à área obstétrica. Relato de Experiência: Trata-se de um estudo descritivo, tipo relato de experiência. Para embasamento metodológico, utilizou-se o método de sistematização de experiências, proposto por Holliday OJ (2006), em que se descreve 1) O ponto de partida; 2) As perguntas iniciais; 3) Recuperação do processo vivido; 4) A reflexão a fundo; 5) Os pontos de chegada. Durante a construção do Procedimento Operacional Padrão (POP), foi possível vivenciar a experiência de trabalho em equipe, com reuniões para construção do protocolo de Identificação, interação entre os residentes com campo de discussões acerca da necessidade real da criação deste instrumento no cenário obstétrico. Considerações Finais: A experiência da elaboração de um POP no processo de formação da residência é vista como uma construção positiva, que leva á a reflexão dos residentes sobre processos necessários para a melhoria na qualidade do serviço de saúde. Destaca-se que o enfermeiro apresenta maior habilidade técnica, agregando cientificidade para desempenhar a aplicabilidade da Segurança do Paciente.
Reflective analysis on patient safety in the hospital context and primary care / Análise reflexiva sobre a segurança do paciente no contexto hospitalar e da atenção primária / Análisis reflexiva sobre la seguridad del paciente en el contexto hospitalario y la atención primaria
Authors: Moura de Abreu Ingrid , Martins Mendes Priscila , Mousinho Tavares Ana Paula , Silva Dantas Avelino Fernanda Valéria , Tolstenko Nogueira Lidya , Santiago da Rocha Silvana 
Published: June 2020

Objetivo: discutir sobre a segurança do paciente no contexto hospitalar e da atenção primária à saúde. Metodologia: estudo reflexivo sobre a temática segurança do paciente a nível primário e a nível hospitalar. Na construção desse trabalho, foi realizado inicialmente um levantamento da literatura acerca do tema, o que possibilitou uma análise contextualizada, além da percepção das autoras a respeito do assunto abordado. Resultados: evidenciou-se que a segurança do paciente deve ser inserida ainda no currículo de formação dos estudantes da área da saúde. No contexto hospitalar ressalta-se a importância da educação permanente entre os colaboradores, proporcionando assim uma cultura de segurança do paciente. Na atenção primária devem ser trabalhados os conceitos básicos para sensibilizar a equipe de saúde sobre a aplicabilidade do tema nesse contexto. Considerações finais: possibilitou a reflexão sobre o fenômeno da segurança do paciente nos dois ambientes de atenção à saúde, mostrando que ainda é mais abordado no âmbito hospitalar e que na atenção primária à saúde foi observada uma a escassez de produções científicas relacionadas a temática.Descritores: Segurança do Paciente. Assistência hospitalar. Atenção primária à saúde.
Pengaruh Sosialisasi Pajak, Penerapan Pp No 46 Tahun 2013 Dan Sanksi Perpajakan Terhadap Kepatuhan Wajib Pajak Badan Umkm Di Sidoarjo
Authors: Octavianingrum Dwi Shinta 
Published: June 2020

Jurnal ini bertujuan untuk mengetahui pengaruh sosialisasi pajak, penerapan PP No 46 Tahun 2013 dan sanksi perpajakan terhadap kepatuhan wajib pajak badan UMKM di Sidoarjo baik secara parsial maupun secara simultan. Penelitian ini juga bertujuan untuk mengetahui variabel independen manakah yang paling mempengaruhi variabel dependen yakni kepatuhan wajib pajak badan UMKM di Sidoarjo.
Metode penelitian yang digunakan dalam penelitian ini adalah pendekatan kuantitatif. Sampel yang digunakan berjumlah 100 diperoleh dengan menggunakan rumus Slovin. Teknik yang digunakan dalam pengambilan sampel adalah dengan teknik NonProbability Sampling. Pengambilan data dilakukan dengan menyebarkan kuisioner. Data dianalisis menggunakan IBM SPSS Statistics 24 dengan teknik analisis regresi linier berganda.
Hasil penelitian menunjukkan bahwa sosialisasi pajak dan sanksi perpajakan berpengaruh secara signifikan terhadap kepatuhan wajib pajak badan UMKM di Sidoarjo. Sedangkan penerapan PP No 46 Tahun 2013 tidak berpengaruh secara parsial terhadap variabel dependen. Namun, simultan ketiga variabel independen berpengaruh secara signifikan terhadap kepatuhan wajib pajak.
Analisis PSAK 109 Terhadap Pengakuan, Pengukuran, Penyajian, dan Pengungkapan Dana Non Halal Periode Januari-Desember 2017 (Studi Kasus Pada LAZ Dompet Amanah Umat Sidoarjo)
Authors: Choir Uswatul 
Published: June 2020

Jurnal ini merupakan hasil penelitian kualitatif yang bertujuan untuk menjawab pertanyaan tentang bagaimana implementasi pengakuan, pengukuran, penyajian, dan pengungkapan dana nonhalal LAZ Dompet Amanah Umat Sidoarjo dan analisisnya.
Metode penelitian yang digunakan adalah kualitatif dengan jenis penelitian studi kasus. Pengumpulan data melalui wawancara dengan bagian keuangan dan sekretaris LAZ Dompet Amanah Umat Sidoarjo dan dokumentasi, teknik analisis data yang digunakan dalam penelitian ini adalah dari hasil wawancara dan dokumentasi, kemudian data yang telah diperoleh diolah dan dianalisis setelah itu disimpulkan dan diinterprestasikan.
Hasil penelitian menunjukkan bahwa amil telah mengakui penambahan dana yang diperoleh dari bunga bank konvensional sebagai dana nonhahal sesuai jumlah yang diterima. Amil pun telah menyajikan dana nonhalal telah terpisah dari dana zakat, infaq, dan sedekah. Akan tetapi, penjurnalan dan pengungkapan di LAZ Dompet Amanah Umat belum sesuai dengan PSAK 109. Amil belum dapat memunculkan keberadaan dana nonhalal pada saat pengungkapannya.
THE PREVALENCE OF PSYCHIATRIC MORBIDITY (SEVERE DEPRESSION & ANXIETY) AMONG ADOLESCENT SCHOOL GIRLS KHARTOUM-SUDAN
Authors: Ali Abuzied Nadia Mahmoud , Ali Kamil M 
Published: June 2020

Background - Psychosomatic health of adolescent girls at crossroads of childhood and mature adulthood, may lead to various health problems in future. To measure the prevalence and identify factors associated with psychiatric morbidity & psychosomatic symptoms among adolescent secondary school girls in Khartoum. Methods - This ‘Study’ was conducted, in three secondary schools of Khartoum North. The Simple Random Sampling Technique was applied to select three schools from the spot map of Khartoum North for this study, and 491 girl students in the adolescent age group were selected from the completed updated list of students from the enrollment registers in these schools. Results - according to the cut-off point (≥ 24 in the G.H.Q -28) findings showed that the prevalence of psychiatric morbidity (severe depression and anxiety) was 60.89% among the adolescent secondary school girls while the psychosomatic disorder was 34.62%. The psychosomatic disorder was found to be significant (P<0.05) with the following three factors: a) late (18-19 yrs.) adolescent age, (61.30%), chi- square= 18.611, df=1, O.R=0.435617 ,CI95%=(0.276629, 0.685981) ; b) physicals abuse (39%) chi- square= 22.34, df =1, O.R=0.281,CI95%=(0.172871, 0.458281) and c) verbal abuse (72%) chi- square= 21.86, df=1, O.R=0.433,CI95%=(0.27331, 0.688). A borderline significant was seen with the family moderate (40%) and low income (40%), chi- square= 5.09, df=2, O.R=(0.839, 0.799),CI95%=((0.508247, 0.503899),( 1.755645 , 1.426668)). However, no significance was there in relation to marital status (married 83.5%), chi- square= 2.324,df=1, O.R=1.06,CI95%=(0.586947,2.197218),mothereducation(elementary61.76%)chisquare=1.692,df=2,O.R=(1,0.951),CI95%=((0.385528,0.554214),(2.674766, 1.626457)) and further education (high level 73 %) chi- square= 3.17, df=2, O.R=(1.282, 1.024),CI95%=((0.354603, 0.55087,)( 4.49567, 1.903074)). Conclusion - Despite the fact that there is no significant (P>0.05) relation between the fathers' level of education and the occurrence of psychosomatic however, the odds ratio of disease is 28% higher among the girls whose fathers were illiterate in comparison to the girls whose fathers were of high level of education. among adolescent school girls.
Optimizing patient outcomes by improving STEMI target times
Authors: Binda Danielle 
Published: June 2020

It is widely recognized that delays in STEMI identification and treatment can negatively affect patient outcomes. Early intervention to achieve reperfusion of the blocked vessel is crucial in minimizing myocardial damage and optimizing patient outcomes.

In April 2017, the Southern Alberta STEMI program identified a delay in SHC ED achieving STEMI target times as outlined by the American College of Cardiology and the American Heart Association.
Of all walk-in STEMI patients presenting to SHC ED between October 2016 and October 2017 requiring urgent transfer to FMC cardiac cath lab:

24% met the ‘Triage to 1st ECG target’ of ≤ 10 mins

6% met the ‘Door in-Door out target’ of ≤ 30 mins

A multi-disciplinary project team was formed to examine barriers to both targets and begin implementing strategies aimed at improving these times.
Történelemkonstruálás – névkonstruálás
Authors: Farkas Tamás 
Published: June 2020

Constructing history – constructing names. Personal names of early Hungarian history and the posterity
The topic of the paper is how people of modern times attempt to approach the onomasticon of personal names of the past, of which they lack sufficient knowledge; and how they create a picture of it for themselves and their peers. The paper presents the topic with the help of examples from different eras and genres of cultural history. The paper is based on sources, originating from centuries later, of personal names of the Hungarian Middle Ages, especially the time of the Hungarian conquest of the Carpathian Basin (the end of the 9th century). In the case of the 13th-century Gesta Hungarorum, the intentions of the author and the methods he applied to create and give personal names to narrate the events of the Conquest, of which he had little knowledge, can be easily identified.
The writers and poets of the end of the 18th and the beginning of the 19th century – which was the era of national awakening, language reform and romanticism – also exemplify how authors could use old or create new personal names in their historical works influenced by the conditions of their era. Continuing the topic, the paper discusses the process and methods of renewing the onomasticon of first names in national contexts, the role of first names registries from this point of view, and how these often paint a misleading picture of their subject, and thus Hungarian history. Finally, the paper deals not only with the laic considerations of our oldest personal names, but also with the problems of their discussion from a historical point of view, emphasizing the need to involve not only historical onomastics but also the approaches of literary onomastics, folk and applied onomastics.
Látszólagos- és valóságosidő-vizsgálatok Pród helynevei körében
Authors: E. Nagy Katalin 
Published: June 2020

Apparent-time and real-time studies of place names in Pród
This paper contains a socio-onomastic examination of the place names of Pród, a small town in Hajdú-Bihar county. The empirical research focuses on the applicability of the apparent-time and real-time studies to the sociology of place names. In a follow-up study (panel study), the author compared the place name knowledge of some residents of Pród in 2013 and in 2019. The panel study revealed that in the six and a half years between the two surveys, children’s and young people’s knowledge of names expanded greatly. In the middle of one’s life, the number of known names – which sometimes increases vastly, in many cases almost doubles – begins to stagnate, and after that only minimal reduction or expansion can be observed in the established toponymic knowledge. This general tendency may be influenced by changes in one’s knowledge of names resulting from unique living situations or life events.
Trends in maternal and child health outcomes in a health systems intervention: a case of Obekai dispensary in western Kenya
Authors: Esamai Fabian , Mwangi Ann , Tabu John , Nangami Mabel , Were Edwin , Ayuku David 
Published: June 2020

Background Maternal, fetal and neonatal mortality are higher in low-income compared to high-income countries primarily due to weak health systems that impede access and utilization of health services. Despite significant improvements in maternal, neonatal and under five children indicators, in some low-income countries, including Kenya these indicators remain relatively high prompting the search for innovative interventions to catalyze the progress towards attaining the Sustainable Development Goal (SDG) 3 target by 2030. We describe the results of a study that assessed the impact of an innovative health systems approach on maternal, neonatal and under-five children outcomes. Methods This was a four year pre-post prospective study to describe trends in the outcomes through the implementation of the Enhanced Health Care (EHC) using the Find Link Treat and Retain (FLTR) strategy. This was implemented in the catchment population of a ‘level 2’ facility, Obekai dispensary in Busia County, Kenya between January 2016 and January 2019. The study population was pregnant women, newborns and under-five children identified and referred to the facility over the study period. Women were identified in the community by community health workers early in pregnancy and followed up in Obekai dispensary until delivery. The newborns were followed up for the whole period the mother baby dyads were in the study. The EHC was implemented on these pairs during the duration of study upto 2-3 years. An interrupted time series model for a single group was used to assess the effect of the intervention on the outcome. Results Attendance in the outpatient, under five and antenatal clinic increased by 76%, 37% and 54% respectively from 2015 to 2018. There was a 90% fully immunization coverage with 97% and 94% BCG and Polio coverage respectively among children studied. There was a 91% facility delivery rate among the pregnant women enrolled in the study. After introduction of FLTR the immunization uptake increased significantly per quarter at a rate of 29.2 (95% confidence interval, CI=20.1-38.3). There was an increase in facility delivery, antenatal (ANC) attendance and decrease in neonatal death after introduction on FLTR. Conclusions Maternal and under-five health indicators in Obekai improved over the study period following the implementation of the EHC package.
Impact of the Insect Growth Regulator Pyriproxyfen on Immature Development, Fecundity, and Fertility of Aedes albopictus
Authors: Rhyne Megan N. , Richards Stephanie L. 
Published: June 2020

ABSTRACT
Aedes albopictus is a vector of several arboviruses; however, control of this day-active species is difficult with ultra-low-volume insecticide treatments applied at dusk/dawn periods. In the current laboratory study, blood-fed Ae. albopictus were exposed to Archer® (insect growth regulator AI: pyriproxyfen) residue in glass bottles (to approximate barrier treatment) and allowed to oviposit. Control mosquitoes were exposed to clean bottles. To evaluate potential dilution effects of water volume, mosquitoes were allowed to oviposit in (relatively) small (59 ml water) or large (177 ml water) containers. The extent to which fecundity (number of eggs laid), fertility rate (number of larvae hatched/number of eggs laid × 100), and emergence rate (number of adults emerged/number of larvae hatched × 100) differed between groups was characterized. In the control group, 18–21 (82–95%) mosquitoes laid eggs, while only 10–11 (45–50%) of mosquitoes in the pyriproxyfen group laid eggs. These sample sizes should be considered when comparing results to other studies. Significantly lower (P = 0.0008) fecundity was observed in mosquitoes exposed to pyriproxyfen (mean ± SE) (small container: 25.2 ± 7.1, large container: 24.3 ± 7.1) compared to control mosquitoes (small container: 49.2 ± 7.8, large container: 52.7 ± 5.2). Regardless of treatment, no significant differences in fecundity were observed between mosquitoes allowed to oviposit in different-sized containers. Hatch rate was significantly lower in the pyriproxyfen group and was impacted by container size (P = 0.032) and treatment (P &lt; 0.0001) (large, control: 61.9% ± 7.8; small, control: 38.0% ± 7.1; large, treated: 10.3% ± 2.4; small, treated: 2.9% ± 1.9). Adult emergence rates were not significantly impacted by treatment or container size. Pyriproxyfen applied as a barrier treatment may be an effective tool for controlling Ae. albopictus.
First Record of Mansonia dyari in the State of Morelos, Mexico, Based on Morphology and COI DNA Barcoding
Authors: Hernández-Guevara Luis F. , Sánchez-Rámos Francisco J. , Chan-Chable Rahuel J. , Hernández-Triana Luis M. , Valdés-Perezgasga Ma. Teresa , González-Acosta Cassandra , Correa-Morales Fabián 
Published: June 2020

ABSTRACTCollections of mosquitoes were conducted for the surveillance of species of medical importance in the state of Morelos, Mexico, in June 2017. Species collected included Mansonia (Mansonia) dyari, which was identified using morphological characters and cytochrome c oxidase I DNA barcoding. Although 3 species of genus Mansonia have been previously reported in Mexico, this is the 1st confirmed record of Ma. dyari in Morelos State, where no Mansonia species had been recorded. Historical records of Ma. dyari and Ma. indubitans in Mexico were reviewed. Therefore, this record increases the number of mosquito species occurring in Morelos to 46. The specimens collected in this study were deposited in the Culicidae collection of the Universidad Autónoma Agraria Antonio Narro, Unidad Laguna.
Music-Educational Activity of Music Art Teacher in the Professional Competence Structure
Authors: Kozhevnikova Larisa 
Published: June 2020

The article outlines the essence of the concept «music- educational activity». It is defined its content and structural components. The interconnected levels of internal regulation of the indicated phenomenon are revealed. Singled out knowledge, abilities, skills, attitudes, which are peculiar indicators of the formation of professional competence of the teacher The focus is on the structural components of musical and educational activities. The personality-qualitative perspectives of professional musical-educational activity are revealed. They are based on informed educational activities as a social phenomenon which leads to the transformation of the general need into the personal and forms a target setting on this basis.The motivational, content, operational and control-estimating in the context of the professional competence of the teacher of musical art is allocated. The need to develop this activity as an integral part in the structure of the professional competence of the teacher of musical art is well-grounded The purpose of the article is to reveal the essence of the concept of «music-educational activitiy» and to substantiate the necessity of mastering this ctivity as an integral part in the structure of professional competence of the teacher.Music-educational activity (MEA) is a process of conscious, active and purposeful interaction of educator as a subject of enlightenment and an audience as an object of enlightenment. This process is predetermined by an independent position of the person in the choice of musical values and is aimed at the dissemination of musical aesthetic knowledge in order to enhance thespiritual development of the person.The Realization of educational activities as a social phenomenon leads to the transformation of the general need into personal, leads to the formation on this basis of the target setting, which determines the personality-quality perspectives of professional MEA.Thus, to summarise, we can assert that MEA is an integral, dynamic system that has its own content, structure, it includes components such as motivational, content, operational and control-evaluation, it is an integral part of the proffessional competency of the music art teacher.