bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reinstatement and revision of the genus Adelmeria (Zingiberaceae) endemic to the Philippines
Authors: Docot Rudolph Valentino A. , Banag Cecilia I. , Poulsen Axel Dalberg 
Published: October 2019

In 1909, Ridley published Adelmeria characterized by its congested terminal inflorescence with large persistent floral bracts. All five species at some point placed in Adelmeria were synonymized in Alpinia by Loesener and subsequent authors. Several phylogenetic studies revealed that Alpinia is highly polyphyletic, suggesting that it should be split into several genera. In the present study, we sampled all five species initially placed in Adelmeria plus additional ones with a similar morphology. The combined analysis of the ITS and trnK/matK regions showed that these species formed a strongly supported monophyletic group inside the Alpinia eubractea clade of the tribe Alpinieae. Although not completely diagnostic, the following morphological characters separate Adelmeria from most of the species currently inside the Alpinia eubractea clade: bilobed ligules; congested inflorescences; utricular bracteoles; sessile flowers; crestless anthers; obovoid fruits. Considering this molecular and morphological evidence, the recognition of Adelmeria is highly justified. In this present paper, we reinstate the genus which is endemic to the Philippines and provide a comprehensive taxonomic revision including a discussion of the application of the name Elmeria. A key to nine species of Adelmeria, four of which (A. dicranochila, A. isarogensis, A. leonardoi, A. undulata) are new to science, is provided as well as full descriptions and preliminary conservation assessments. Interestingly, monoecy was observed in A. oblonga and reported for the first time for Adelmeria. Four lectotypes and one epitype are designated in this study.
Sales data as a measure of antibiotics usage: Concepts, examples and discussion of influencing factors
Authors: Merle Roswitha , Meyer‐Kühling Borris 
Published: October 2019

AbstractMonitoring and surveillance of antimicrobial usage in animals is a public health concern and different methods are currently discussed widely in public, science and politics. The objective of the paper is to present the available methods of monitoring and to discuss possible differences in the assessment of the antibiotics treatment. Sales data are expressed as the average amount of substance per animal or kg live weight (e.g. population‐corrected unit, PCU). The number of Defined Daily Doses (nDDDvet) is calculated by extrapolating sales data with average animal weights and defined drug doses to a number of treatments theoretically applied to animals. In contrast, the number of Used Daily Doses (nUDDvet) displays the actual number of treatments which have been applied. As sales data are relatively easily obtained, they are frequently used. However, their results are influenced by the composition of the population and by the dose of the substances. As both may vary strongly between countries, direct comparison of sales data between countries may be misleading. The concept of analysing sales data is shown by exemplarily using the methods in the ESVAC report 2015. The presentation of usage data in terms of nDDDvet or of nUDDvet increases the comparability of the data from different countries or time periods. Furthermore, fluoroquinolones and third‐/fourth‐generation cephalosporins which, among other substances, bare a potential risk for human health, are used at low doses. Hence, their use contributes to a sales reduction while contrasting the guidelines of prudent use. nDDDvet or nUDDvet have the ability to better reflect the treatment frequency and thus to better link antibiotics use to public health concerns. Quantification of antibiotics should assist to focus on prudent use of antimicrobials to reduce the burden of resistant bacteria and, thus, enhance public health, animal health and animal welfare.
Subsystem trace distance in low-lying states of (1 + 1)-dimensional conformal field theories
Authors: Zhang Jiaju , Ruggiero Paola , Calabrese Pasquale 
Published: October 2019

AbstractWe report on a systematic replica approach to calculate the subsystem trace distance for a quantum field theory. This method has been recently introduced in [J. Zhang, P. Ruggiero and P. Calabrese,Phys. Rev. Lett.122(2019) 141602], of which this work is a completion. The trace distance between two reduced density matricesρAandσAis obtained from the moments tr(ρA− σA)nand taking the limitn →1 of the traces of the even powers. We focus here on the case of a subsystem consisting of a single interval of lengthℓembedded in the low lying eigenstates of a one-dimensional critical system of lengthL, a situation that can be studied exploiting the path integral form of the reduced density matrices of two-dimensional conformal field theories. The trace distance turns out to be ascale invariant universal functionofℓ/L. Here we complete our previous work by providing detailed derivations of all results and further new formulas for the distances between several low-lying states in two-dimensional free massless compact boson and fermion theories. Remarkably, for one special case in the bosonic theory and for another in the fermionic one, we obtain the exact trace distance, as well as the Schattenn-distance, for an interval of arbitrary length, while in generic case we have a general form for the first term in the expansion in powers ofℓ/L. The analytical predictions in conformal field theories are tested against exact numerical calculations in XX and Ising spin chains, finding perfect agreement. As a byproduct, new results in two-dimensional CFT are also obtained for other entanglement-related quantities, such as the relative entropy and the fidelity.
Construction of advanced producers of first- and second-generation ethanol in Saccharomyces cerevisiae and selected species of non-conventional yeasts (Scheffersomyces stipitis, Ogataea polymorpha)
Authors: Ruchala Justyna , Kurylenko Olena O , Dmytruk Kostyantyn V , Sibirny Andriy A 
Published: October 2019

Abstract
This review summarizes progress in the construction of efficient yeast ethanol producers from glucose/sucrose and lignocellulose. Saccharomyces cerevisiae is the major industrial producer of first-generation ethanol. The different approaches to increase ethanol yield and productivity from glucose in S. cerevisiae are described. Construction of the producers of second-generation ethanol is described for S. cerevisiae, one of the best natural xylose fermenters, Scheffersomyces stipitis and the most thermotolerant yeast known Ogataea polymorpha. Each of these organisms has some advantages and drawbacks. S. cerevisiae is the primary industrial ethanol producer and is the most ethanol tolerant natural yeast known and, however, cannot metabolize xylose. S. stipitis can effectively ferment both glucose and xylose and, however, has low ethanol tolerance and requires oxygen for growth. O. polymorpha grows and ferments at high temperatures and, however, produces very low amounts of ethanol from xylose. Review describes how the mentioned drawbacks could be overcome.
Factors driving Arabian gazelles (Gazella arabica) in Israel to extinction: time series analysis of population size and juvenile survival in an unexploited population
Authors: Shalmon Benny , Sun Ping , Wronski Torsten 
Published: October 2019

AbstractWild populations of Arabian gazelles (Gazella arabica) were once common on the Arabian Peninsula, but today disappeared from large parts of their former range. In Israel only a small population of currently 30 individuals survived, although it was—and still is—well protected from illegal hunting and habitat destruction. In our study we aimed to identify the factors influencing the population growth ofG. arabicain Israel over the last two decades (1995–2017). We tested the impact of five environmental variables including annual mean maximum temperature, rainfall, the availability of two major food plants, competition with sympatric dorcas gazelle (G. dorcas) and predation (mainly by wolves) on two dependent variables relating to population viability (population size, percentage fawn survival) using a retrospective time series analysis. After testing for autocorrelations, two generalized least squares (GLS) models with autocorrelations at 3 and 6 years [GLS-AR(3, 6)] were identified as the best models to explain environmental effects on populations size. Wolf encounter rate had a significant negative effect onG. arabicapopulation size, whileG. dorcaspopulation size had a significant positive effect, suggesting that wolf predation shapes the population size of both gazelle species. For percentage fawn survival, model residuals did not reveal any significant autocorrelation and the best fit GLS-AR(0) model retained only wolf encounter rate and mean annual maximal temperature as significant predictors. This result suggests a strong impact of wolf predation and increasing temperatures on the fawn survival of Arabian gazelles. Changed rainfall patterns, food availability and competition between gazelle species had no impact on fawn survival.
Design of Complex Oxide Interfaces by Oxide Molecular Beam Epitaxy
Authors: Suyolcu Y. E. , Christiani G. , van Aken P. A. , Logvenov G. 
Published: October 2019

Abstract
Complex oxides provide a versatile playground for many phenomena and possible applications, for instance, high-temperature superconductivity, magnetism, ferroelectricity, metal-to-insulator transition, colossal magnetoresistance, and piezoelectricity. The origin of these phenomena is the competition between different degrees of freedom such as charge, orbital, and spin, which are interrelated with the crystal structure, the oxygen stoichiometry, and the doping dependence. Recent developments not only in the epitaxial growth technologies, such as reactive molecular beam epitaxy, but also in the characterization techniques, as aberration-corrected scanning transmission electron microscopy with spectroscopic tools, allow synthesizing and identifying epitaxial systems at the atomic scale. Combination of different oxide layers opens access to interface physics and leads to engineering interface properties, where the degrees of freedom can be artificially modified. In this review, we present different homo- and hetero-epitaxial interfaces with extraordinary structural quality and different functionalities, including high-temperature superconductivity, thermoelectricity, and magnetism.
Dehydroepiandrosterone Supplementation May Benefit Women with Asthma Who Have Low Androgen Levels: A Pilot Study
Authors: Marozkina Nadzeya , Zein Joe , DeBoer Mark D. , Logan Laurie , Veri Laura , Ross Kristie , Gaston Benjamin 
Published: October 2019

ABSTRACT

Introduction
Among individuals with severe asthma, FEV1 is low in individuals with low dehydroepiandrosterone (DHEA) sulfate (DHEAS) levels. In the Severe Asthma Research Program (SARP), no women with DHEAS > 200 μg/dL had an FEV1 < 60% predicted. DHEA has benefited patients with COPD and pulmonary hypertension in small trials. Therefore, we hypothesized that DHEA supplementation may improve FEV1 in asthmatic women with low DHEAS.

Methods
Premenopausal, nonsmoking, otherwise healthy women, 18-50 years old, with mild or moderate asthma and baseline FEV1 > 60% predicted received 100 mg DHEA orally every 12 h for 2 weeks. Spirometry and DHEAS were measured at the initial visit and 2 weeks later, after completion of DHEA treatment. Based on our previous work, the primary outcome variable for this pilot study was post-albuterol spirometry in the low-DHEAS group. Subjects also continued their other routine asthma management.

Results
Serum DHEAS increased with DHEA treatment in women with starting DHEAS < 200 µg/dL: this increase was from 71 ± 23 to 725 ± 295 µg/dL (n = 10; p = 0.0001). The increase in the high-DHEAS group was smaller. Post-albuterol FEV1 increased by 51 mL, from 3.026 ± 0.5 to 3.077 ± 0.49 L (n = 10; p = 0.034 by paired t test, significant after Bonferroni), in women with low DHEAS. In the high-DHEAS group (baseline DHEAS ≥ 200 µg/dl), post-albuterol FEV1 did not change significantly (n = 3, p = NS). Three subjects were excluded: one had comorbid COPD, one could not perform spirometry, and one did not take the DHEA. There were no adverse effects of DHEA treatment in this trial.

Conclusions
Endocrine treatments (corticosteroids) are a mainstay of anti-inflammatory management for moderate and severe asthma. Their use has improved asthma outcomes. Androgens also reduce airway inflammation and promote airway smooth muscle relaxation, but are rarely used clinically for asthma treatment. Our results suggest that the over-the-counter steroid DHEA may improve lung function in asthma outcomes among women with DHEAS < 200 ug/dL.
Who benefits from R0 resection? A single‐center analysis of patients with stage Ⅳ gallbladder cancer
Authors: Chen Chen , Wang Lin , Zhang Rui , Li Qi , Zhao Ya‐Ling , Zhang Guan‐Jun , Li Wen‐Zhi , Geng Zhi‐Min 
Published: October 2019

AbstractObjectivesMost patients with gallbladder cancer (GBC) present with advanced‐stage disease and have a poor prognosis. Radical resection remains the only therapeutic option to improve survival in patients with GBC. This study aimed to analyze the prognostic factors in patients with stage Ⅳ GBC and to identify a subgroup of patients who might benefit from R0 resection.MethodsA total of 285 patients with stage Ⅳ GBC were retrospectively analyzed at our institution from January 2008 to December 2012. Factors potentially influencing the prognosis of GBC after surgery were analyzed by univariate and multivariate analyses.ResultsThe 1‐, 3‐, and 5‐year overall survival rates were 6.6% (15/229), 0.9% (2/229), and 0 (0/229), respectively. Ascites (relative risk [RR] = 1.631, 95% confidence interval [CI]: 1.221–2.180, P = 0.001), pathological grade (RR = 1.337, 95% CI: 1.050–1.702, P = 0.018), T stage (RR = 1.421, 95% CI: 1.099–1.837, P = 0.000), M stage (RR = 1.896, 95% CI: 1.409–2.552, P = 0.000), and surgery (RR = 1.542, 95% CI: 1.022–2.327, P = 0.039) were identified as independent risk factors influencing prognosis. The median survival time (MST) was significantly higher in patients undergoing R0 resection than in those undergoing R1/R2 resection (6.0 vs. 2.7 months; P < 0.001). In subgroup analyses, stage ⅣA patients benefited from R0 resection (MST for R0 vs. R1/R2, 11.0 vs. 4.0 months; P = 0.003), while R0 resection had a significant survival benefit than R1/R2 resection in patient with stage ⅣB GBC without distant metastasis (MST for R0 vs. R1/R2, 6.0 vs. 3.0 months; P = 0.007).ConclusionAscites, pathological grade, T stage, M stage, and surgery were independent risk factors influencing prognosis in patients with stage IV GBC. N2 lymph node metastasis did not preclude curative resection, and radical resection should be considered in patients with stage Ⅳ GBC without distant metastasis once R0 margin was achieved.
Reducing speed commands in interval management with speed planning
Authors: Riedel T. , Takahashi M. , Itoh E. 
Published: October 2019

ABSTRACTFlight-deck Interval Management (FIM) is a modern airborne self-spacing technology that improves arrival route throughput and runway utilisation and increases hourly arrival capacity by up to four aircraft per hour and per runway, compared to conventional air traffic controller guided arrivals. The National Aeronautics and Space Administration (NASA) has been the leader in FIM research and formulated a logic that was put to an actual flight test in 2017. Despite the overall success of the project, operational deficiencies concerning the number of speed commands, which led to several recommendations for future research before operational implementation, were discovered. In this study, a new logic that implements a two-stage rule-based selection algorithm was developed to overcome those deficiencies. The proposed logic was compared to NASA’s logic on an arrival in Tokyo International Airport with multiple induced error patterns. The results indicate that the new logic significantly decreases the number of speed commands with only minor aggravations in spacing performance. The results that highlight the strengths and weaknesses of both concepts are discussed, and an outlook on and ideas for future research on FIM and the proposed logic are presented.
Canada’s Treatment of Non-Citizens through the Lens of the United Nations Individual Complaints Mechanisms
Authors: ATAK IDIL , GIFFIN LORIELLE 
Published: October 2019

AbstractThe United Nations (UN) human rights treaty bodies play an important role in defining the scope and the nature of non-citizens’ rights. This article offers a critical overview of the UN human rights case law from 2008 to 2018 pertaining to non-citizens — notably undocumented migrants, refused asylum seekers, and permanent residents ordered deported — in Canada. It examines the jurisprudence of the three UN human rights treaty bodies recognized by Canada as having competence to receive and consider individual complaints — namely, the UN Human Rights Committee, the Committee against Torture, and the Committee on the Elimination of Discrimination against Women. The purpose of this examination is two-fold. First, it intends to foster a better understanding of the cases lodged by non-citizens before the UN human rights treaty bodies. The second aim is to explore the substantive issues that the UN committees’ jurisprudence on non-citizens reveals about Canada’s immigration decision-making and enforcement. It is argued that some groups of non-citizens in Canada are at risk of being deported to persecution or hardship in violation of the non-refoulement principle and Canada’s international human rights obligations. The article illuminates several loopholes identified by the UN treaty bodies in Canada’s immigration and refugee protection system that heighten the risk of refoulement.
Team Rubicon Medical Response to Hurricane Dorian in the Bahamas
Authors: Bouland Andrew J. , Selzer Jordan , Yogman Madi , Callaway David W. 
Published: October 2019

ABSTRACTOn September 1, 2019, Hurricane Dorian made landfall as a category 5 hurricane on Great Abaco Island, Bahamas. Hurricane Dorian matched the “Labor Day” hurricane of 1935 as the strongest recorded Atlantic hurricane to make landfall with maximum sustained winds of 185 miles/h.1 At the request of the Government of the Bahamas, Team Rubicon activated a World Health Organization Type 1 Mobile Emergency Medical Team and responded to Great Abaco Island. The team provided medical care and reconnaissance of medical clinics on the island and surrounding cays…
Sticky security: the collages of tracking device advertising
Authors: Leander Anna 
Published: October 2019

AbstractIn security studies and beyond, technological developments are associated with technocratic, rationalistic, transparent forms of security governed from a distance. In much of the advertising of tracking devices the associations made are very different not to say opposed to this. The advertising composes security anchored in sensemaking and resonance rather than calculus and reason, working from within and below rather than from a above at distance and depending on the negotiation of opaque co-presences rather than the establishment of precision and transparency. The consequence is that advertising not only extends but also deepens the grip of military/security matters: making them sticky. Moreover, the heterogeneity of the elements is such that what is composed is a shifting collage rather than a stable composition. This argument makes a threefold contribution to security studies: a theoretical reconceptualisation of what it means to compose security, an empirical intervention in the debates surrounding the politics of tracking devices and a methodological intervention in favour of collaborationist research strategies.
Prevalence, correlates and help-seeking behaviour for depressive symptoms in rural Uganda: a population-based survey
Authors: Ssebunnya J. , Medhin G. , Kangere S. , Kigozi F. , Nakku J. , Lund C. 
Published: October 2019

Background.Depression is a common disorder characterized by delayed help-seeking, often remaining undetected and untreated.Objectives.We sought to estimate the proportion of adults in Kamuli District with depressive symptoms and to assess their help-seeking behaviour.Methods.This was a population-based cross-sectional study conducted in a rural district in Uganda. Sampling of study participants was done using the probability proportional to size method. Screening for depression was done using Patient Health Questionnaire (PHQ-9). The participants who screened positive also reported on whether and where they had sought treatment. Data collected using PHQ-9 was used both as a symptom-based description of depression and algorithm diagnosis of major depression. All data analysis was done using STATA version 13.Results.With a cut-off score of ⩾10, 6.4% screened positive for current depressive symptoms and 23.6% reported experiencing depressive symptoms in the past 12 months. The majority of individuals who screened positive for current depression (75.6%) were females. In a crude analysis, people with lower education, middle age and low socio-economic status were more likely to have depressive symptoms. Help-seeking was low, with only 18.9% of the individuals who screened positive for current depression having sought treatment from a health worker.Conclusion.Depressive symptoms are common in the study district with low levels of help-seeking practices. People with lower levels of education, low socio-economic status and those in middle age are more likely to be affected by these symptoms. Most persons with current depression had past history of depressive symptoms.
Psychologists’ motivations for integrating apps into therapy with secondary school-aged young people
Authors: Gindidis Simone , Stewart Sandra E. , Roodenburg John 
Published: October 2019

AbstractPsychologists play an important role in the provision of mental health support to young people. Some psychologists are incorporating apps into therapy with young people; however, little is understood about why such incorporation is taking place. Ten semi-structured qualitative interviews exploring why psychologists augment therapy by recommending or using apps alongside therapy were undertaken. Findings suggest that psychologists were prompted to update their therapeutic approach in response to client-initiated discussion of apps. Personal use of apps, higher engagement in therapy, increased access to therapeutic strategies between sessions, and a reduction of the stigma associated with externalising therapeutic strategies were also facilitating factors. Implications for practice such as apps currently complementing structured therapy over unstructured talk therapy, and further research are explored.
A comprehensive review of otorhinolaryngological global health concerns
Authors: Murphy Declan C 
Published: October 2019

AbstractBackgroundENT disease prevalence, risk factors and treatment vary between developed and developing countries. Health provision, particularly disease prevention strategies and surgery, in developing countries is poor, manifesting as a high frequency of common and preventable diseases. Healthcare systems in developing countries are unsustainable, and the technological advances that provide ENT surgery with novel diagnostic and treatment opportunities are inaccessible.ConclusionA multifaceted approach is essential to improve the care of patients with ENT diseases in developing countries. Public health efforts must focus on educating the local community, reducing high-risk behaviours and decreasing the frequency of preventable diseases. Governments must be pressured to prioritise the funding of long-term, sustainable efforts with effective disease prevention strategies. Providing local healthcare professionals with high-quality ENT training so that self-sustaining and low-cost care can be delivered, mainly in a primary care setting, is key.