bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Influence of Resected Gastric Weight upon Weight Loss after Sleeve Gastrectomy
Authors: Rosas Ulysses , Hines Harrison , Rogan Daniel , Rivas Homero , Morton John 
Published: June 2020

Bariatric surgery is an effective and enduring treatment for obesity. Sleeve gastrectomy (SG) has emerged as an increasingly prevalent surgical intervention. Further investigation is required to determine optimal standardization of SG. Data were collected prospectively for 64 patients who underwent a laparoscopic vertical SG between December 2010 and February 2013 at a single academic institution. Demographic, intraoperative, and postoperative (postop) data were collected for all patients including weighing each resected stomach. The total resected gastric weight varied widely. Preoperatively, patients in the upper tercile for resected gastric weight were more likely to be male (lower 10%, middle 23%, upper 52%, P = 0.006) and had greater initial weights (lower 255.9%, middle 245.1%, upper 280.0%, P = 0.019). The resected gastric weight (g) varied by tercile (mean of all, 131.24 ± 39.8; lower, 93.9 ± 10.9; middle, 127.4 ± 11.7; upper 172.7 ± 37.9, P = 0.000). Patients were followed for 1-year postop with follow-up data for 94 per cent (60/64) of participants. Per cent excess weight loss (EWL) was obtained at three, six, and 12 months postop. At 12 months, there was a trend toward increased per cent EWL in the upper tercile (lower 61.1%, middle 54.1%, upper 90.5%, P = 0.057). In conclusion, while the amount of gastric sleeve resected can vary, this study shows that intraoperative assessment of resected sleeve weight can help evaluate adequacy of resection. Improved 12-month per cent EWL in patients with greater resected tissue demonstrate potentially improved outcomes.
Right Patient, Right Place, Right Time: Field Triage and Transfer to Level I Trauma Centers
Authors: Gough Benjamin L. , Painter Matthew D. , Hoffman Autumn L. , Caplan Richard J. , Peters Cynthia A. , Cipolle Mark D. 
Published: June 2020

Introduction This study sought to compare the outcomes of trauma patients taken directly from the field to a level I trauma center (direct) versus patients that were first brought to a level III trauma center prior to being transferred to a level I (transfer) within our inclusive Delaware trauma system. Methods A retrospective review of the level I center’s trauma registry was performed using data from 2013 to 2017 for patients brought to a single level I trauma center from two surrounding counties. The direct cohort consisted of 362 patients, while the transfer cohort contained 204 patients. Linear regression analysis was performed to investigate hospital length of stay (LOS), while logistic regression was used for mortality, complications, and craniotomy. Covariates included age, gender, county, and injury severity score (ISS). Propensity score weighting was also performed between the direct and transfer cohorts. Results When adjusting for age, gender, ISS, and county, transferred patients demonstrated worse outcomes compared to direct patients in both the regression and propensity score analyses. Transferred patients were at increased risk of mortality (OR 2.17, CI 1.10-4.37, P = .027) and craniotomy (OR 3.92, CI 1.87-8.72, P < .001). Age was predictive of mortality ( P < .001). ISS was predictive of increased risk of mortality ( P < .001), increased LOS ( P < .001), and craniotomy ( P < .001). Older age, Sussex County, and higher ISS were predictive of patients being transferred ( P < .001). Discussion Delays in presentation to our level I trauma center resulted in worse outcomes. Patients that meet criteria should be considered for transport directly to the highest level trauma center in the system to avoid delays in care.
Is Primary Tumor Excision and Specific Metastases Sites Resection Associated With Improved Survival in Stage Ⅳ Colorectal Cancer? Results From SEER Database Analysis
Authors: Yi Chenghao , Li Jinpeng , Tang Fuxin , Ning Zhikun , Tian Huakai , Xiao Longlin , Wang Anan , Zong Zhen 
Published: June 2020

Objective We aimed to explore the prognostic value of primary tumor and specific metastases excision on survival among patients with stage IV colorectal cancer (CRC) in the Surveillance, Epidemiology, and End Results (SEER) database. Methods Patients with stage IV CRC were selected using SEER database between 2010 and 2013. Survival rate was calculated according to the Kaplan-Meier method, and differences between curves were tested by the log-rank test. Cox proportional hazards model was used in the multivariable analysis. Results Included in this study were 27 878 patients with distant metastatic CRC. Among the single organ site of metastatic CRC, patients with solitary metastasis of lung showed the highest median overall survival (OS). Both primary and metastatic sites surgical resection for patients with liver, lung, and simultaneous liver and lung metastases had better median OS. Age younger than 65 years, Asian and Pacific Islander, distal colon and rectum, and palliative primary tumor and metastatic lesions resection were associated with better OS after multivariate analysis. Palliative primary tumor and metastatic lesions resection had a significant survival benefit compared with nonsurgical group in selected patients. Conclusion These findings support the use of preemptive surgery in the management of highly selected metastatic CRC patients.
Predicting Aggressive Behavior in Nonfunctional Pancreatic Neuroendocrine Tumors With Emphasis on Tumor Size Significance and Survival Trends: A Population-Based Analysis of 1787 Patients
Authors: Fathi Amir H. , Romanyshyn Jonathan , Barati Mehdi , Choudhury Uzair , Chen Allen , Sosa Julie Ann 
Published: June 2020

Background Nonfunctional pancreatic neuroendocrine tumors (NF-PNETs) are rare tumors with continued controversies in management. This study aims to identify demographic and clinicopathologic characteristics associated with aggressive behavior and survival. Methods The Surveillance, Epidemiology, and End Results database was used to identify patients with NF-PNETs from 1988 to 2012. Multivariate regression analysis and Cox proportional hazards modeling were used to assess the impact of patient, tumor, and treatment characteristics on tumor behavior and overall survival. Results In 1787 patients identified, size was a major determinant of aggressive behavior. The probability of aggressiveness increased 100% for tumor size ≥2 cm. For tumors ≥2 cm, every 1-cm increase in size was associated with an increase in probability of aggressive behavior by 11.3%. Patient age, tumor grade, and surgical resection were independent predictors of survival. Surgical resection was associated with improved survival but not grade I or II tumors with size <2 cm. Discussion Patient age, tumor size, and grade should be in the decision-making process around the surgical management of NF-PNETs. For tumors ≤2 cm with histologic grades of I or II, the probability of aggressive behavior is low, and surgical resection does not appear to afford survival benefit. Therefore, close observation could be justified.
Systems modelling and simulation to inform strategic decision making for suicide prevention in rural New South Wales (Australia)
Authors: Atkinson Jo-An , Skinner Adam , Hackney Sue , Mason Linda , Heffernan Mark , Currier Dianne , King Kylie , Pirkis Jane 
Published: June 2020

Background: The need to understand and respond to the unique characteristics and drivers of suicidal behaviour in rural areas has been enabled through the Australian Government’s 2015 mental health reforms facilitating a move to an evidence-based, regional approach to suicide prevention. However, a key challenge has been the complex decision-making environment and lack of appropriate tools to facilitate the use of evidence, data and expert knowledge in a way that can inform contextually appropriate strategies that will deliver the greatest impact. This paper reports the co-development of an advanced decision support tool that enables regional decision makers to explore the likely impacts of their decisions before implementing them in the real world. Methods: A system dynamics model for the rural and remote population catchment of Western New South Wales was developed. The model was based on defined pathways to mental health care and suicidal behaviour and reproduced historic trends in the incidence of attempted suicide (self-harm hospitalisations) and suicide deaths in the region. A series of intervention scenarios were investigated to forecast their impact on suicidal behaviour over a 10-year period. Results: Post-suicide attempt assertive aftercare was forecast to deliver the greatest impact, reducing the numbers of self-harm hospitalisations and suicide deaths by 5.65% (95% interval, 4.87−6.42%) and 5.45% (4.68−6.22%), respectively. Reductions were also projected for community support programs (self-harm hospitalisations: 2.83%, 95% interval 2.23−3.46%; suicide deaths: 4.38%, 95% interval 3.78−5.00%). Some scenarios produced unintuitive impacts or effect sizes that were significantly lower than what has been anticipated under the traditional evidence-based approach to suicide prevention and provide an opportunity for learning. Conclusion: Systems modelling and simulation offers significant potential for regional decision makers to better understand and respond to the unique characteristics and drivers of suicidal behaviour in their catchments and more effectively allocate limited health resources.
Significant Published Articles for Pharmacy Nutrition Support Practice in 2019
Authors: Dickerson Roland N. , Bingham Angela L. , Canada Todd W. , N. Chan Lingtak , Cober M. Petrea , V. Cogle Sarah , Tucker Anne M. , Kumpf Vanessa J. 
Published: June 2020

Purpose The purpose of this article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Methods: Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2019 considered important to their clinical practice. The citation list was compiled into a single spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice. A culled list of publications was then identified whereby at least 5 out of the 8 author participants considered the paper to be important. Guideline and consensus papers from professional organizations, important to practice but not ranked, were also included. Results: A total of 111 articles were identified; 6 from the primary literature were voted by the group to be of high importance. An additional 9 organizational guidelines, position, recommendation, or consensus papers were also identified. The top-ranked articles from the primary literature were summarized and a narrative regarding its implications to pharmacy nutrition support practice were provided. Conclusion: We recommend that pharmacists engaged in nutrition support therapy be familiar with these articles as it pertains to their practice.
The Effect of Doll Therapy on Agitation and Cognitive State in Institutionalized Patients With Moderate-to-Severe Dementia: A Randomized Controlled Study
Authors: Yilmaz Cemile Kütmeç , Aşiret Güler Duru 
Published: June 2020

This study is aimed at identifying the effect of doll therapy on agitation and cognitive state in institutionalized patients with moderate-to-severe dementia. This randomized controlled experimental study was conducted from April 8, 2019, to October 30, 2019, in a nursing home in Aksaray, Turkey. In total, 29 people with dementia participated in this study, 15 of whom comprised the intervention group. The control group, in which no intervention was made, was composed of the remaining 14 individuals. Data were collected using the introductory information form and the Standardized Mini-Mental State Examination (SMMSE) to evaluate cognitive status, and the Neuropsychiatric Inventory (NPI) and Cohen-Mansfield Agitation Inventory (CMAI) to evaluate behavioral disturbances. Patients with dementia in the intervention group received doll therapy for 8 weeks. We found that there was no statistically significant change between fourth- and eighth-week SMMSE scores for either the intervention or control groups ( P > .05), while there was a significant change in the CMAI and NPI scores of the intervention group ( P < .05). This study found that doll therapy was effective in decreasing agitation and behavioral problems in people diagnosed with moderate-to-severe dementia. Trial registration: ClinicalTrials.gov , ID: NCT04120103 Retrospectively registered on 8 April 2019.
Young- and Late-Onset Dementia: A Comparative Study of Quality of Life, Burden, and Depressive Symptoms in Caregivers
Authors: Kimura Nathália R. S. , Simões José Pedro , Santos Raquel Luiza , Baptista Maria Alice Tourinho , Portugal Maria da Glória , Johannessen Aud , Barca Maria Lage , Engedal Knut , Laks Jerson , Rodrigues Valeska Marinho , Dourado Marcia C. N. 
Published: June 2020

Objective: To compare the quality of life, burden, and depressive symptoms of caregivers of individuals with young-onset dementia (YOD) and late-onset dementia (LOD). Methods: Using a cross-sectional design, a convenience sample of 110 dyads of individuals with dementia and their caregivers, all living in the community, was included. The care recipients completed assessments about cognition, quality of life, and awareness of disease. Caregivers’ quality of life, resilience, depressive and anxiety symptoms, hopelessness, and burden of care were assessed. Results: A significant difference was found in caregivers’ burden and depressive symptoms according to the age of onset. However, there was no difference in caregivers’ quality of life between YOD and LOD groups. In both groups, a linear regression analysis indicated that caregivers’ perspective of quality of life of care recipient and caregivers’ hopelessness were associated with their quality of life. In addition, in the LOD group, caregivers’ burden was associated with their perspective of the quality of life of care recipient, type of kinship, and presence of emotional problems. In the YOD group, caregivers’ burden was associated with duration of caregiving role, cohabitating with care recipient, and their anxiety symptoms. Caregivers’ depressive symptoms were associated with anxiety symptoms in the YOD group, whereas hopelessness was associated with caregivers’ depressive symptoms in both the groups. Conclusion: Our findings suggest that the factors that affect quality of life, burden, and depressive symptoms of caregivers of individuals with LOD differ from those that affect the caregivers of individuals with YOD.
Pharmacist-Driven Implementation of Outpatient Antibiotic Prescribing Algorithms Improves Guideline Adherence in the Emergency Department
Authors: Stoll Kristin , Feltz Erik , Ebert Steven 
Published: June 2020

Background: Inappropriate prescribing of antibiotics has been identified as the most important modifiable risk factor for antimicrobial resistance. Objective: The purpose of this project was to improve guideline adherence and promote optimal use of outpatient antibiotics in the emergency department (ED). Methods: Prescribing algorithms for community-acquired pneumonia (CAP), skin and soft tissue infections (SSTI), and urinary tract infections (UTI) were developed to integrate clinical practice guideline recommendations with local ED antibiogram data. Outcomes were evaluated through chart review of patients prescribed outpatient antibiotics by ED providers. The primary outcome was adherence to clinical practice guidelines, defined as the selection of an appropriate antibiotic agent, dose, and duration of therapy for each patient discharged. Results: When compared to patients discharged from the ED prior to algorithm implementation (N = 325), the post-implementation group (N = 353) received more antibiotic prescriptions that were completely guideline adherent (61.5% vs 11.7%, P < .00001). Post-implementation discharge orders demonstrated improvement in the selection of an appropriate agent (87.3% vs 45.5%, P < .00001), dose (91.5% vs 77.2%, P < .00001), and duration of therapy (71.1% vs 39.1%, P < .01). Additionally, fluoroquinolone prescribing rates were reduced (2.3% vs 12.3%, P < .00001). A reduction in all-cause 30-day returns to the ED or urgent care was observed (15.3% vs 21.5%, P = .036). Conclusion: Pharmacist-driven implementation of antibiotic prescribing algorithms improved guideline adherence in the outpatient treatment of CAP, SSTI, and UTI.
Pathogenic language in psychiatric practice and how to combat it
Authors: Bloch Sidney , Haslam Nick 
Published: June 2020

Objective: Psychiatrists are susceptible intermittently to use dehumanising terms in their clinical practice, which arguably harm patients and their families. Our goal is to shed light on this unwelcome phenomenon and to develop the means to combat it. Method: We have examined journal articles, books on the history of psychiatry, and educational material devised for psychiatric patients, for evidence of what we have called ‘pathogenic language’. We have also sought colleagues’ reflections on the subject. Results: We have identified several terms that are ostensibly pathogenic, tried to illuminate their intrinsic features and devised guidelines to stem their use. Conclusions: Psychiatrists have the potential to harm patients and their families by using pathogenic language when communicating with them. We conclude that meticulous attention to this risk, coupled with appropriate ethically based and educational strategies, can contribute to the eradication of pathogenic language and prevent its recurrence.
A Study of Cognitive Results in Marketing and Finance Students
Authors: Ortiz-Rendón Paola Andrea , Montoya-Restrepo Luz Alexandra , Munuera-Alemán Jose-Luis 
Published: June 2020

Background. It is undeniable that human capital is a highly valued resource in today’s increasingly competitive and interconnected world. Management education involving decision-making is a fundamental issue in today’s education systems. Particularly, the marketing audit improves the decision-making process based on the assessment of the marketing performance and the analysis of the market results. Although marketing audits are not widely used among organizations yet, marketing control mechanisms have become more important in organizational performance studies and must be integrated into marketing and finance education programs. Method. This quasi-experimental study followed a pretest/posttest design to measure differences in the scores 281 marketing and finance students in Colombia taking part in a game of marketing audit. Results and conclusion. All students significantly improved their higher grades after taking part in the game. Marketing and finance students also improved their responses. For the students in the final semester and for the male and mixed groups, there is insufficient evidence to suggest that the game can improve their cognitive results. Decisions between marketing and finance professionals must be reinforced, to allow academic organizations involved in developing markets and characterized by low levels of competitiveness improve their education levels.
Exploring the Effects of Violent Video Games on Healthcare Trainees
Authors: Krause Karlie A. , Smyth Chelsie , Jansen Kate L. 
Published: June 2020

Background. The prevalence of video game play has continued to increase. Previous literature has suggested negative emotional consequences related to violent video game play, such as an increase in aggression and decrease in empathy. Healthcare providers require high levels of empathy to effectively work with patients. The purpose of this study was to explore the effects of video games on empathy on a sample of graduate-level healthcare trainees. Methods. A sample of 81 students on a healthcare campus completed a 30-item survey assessing video game habits and empathy levels. Participants were then placed into two groups (violent and non-violent) based on the amount of video game violence they are exposed to. Results. The results revealed no differences between healthcare trainees on overall empathy. A follow-up analysis examining individual subscales that comprise the overall empathy score, indicated the violent video game players had lower scores on the Personal Distress scale. Conclusion. Findings suggest that healthcare trainees who play violent video games do not experience decreased Empathic Concern or Perspective Taking, compared to individuals who do not play violent games. However, healthcare trainees who play violent video games indicated lower levels of Personal Distress. Given the intensity in healthcare settings, findings suggest violent video game play may be adaptive to healthcare trainees, as lower personal distress can lead to better decision-making and potentially prevent burnout. Further research is necessary to determine the role of video game play in healthcare professionals.
A new type of damper combining eddy current damping with rack and gear
Authors: Li Yafeng , Li Shouying , Wang Jianzhong , Chen Zhengqing 
Published: June 2020

A new type of damper combining eddy current damping with rack and gear, which can simultaneously export damping and inertial forces, is proposed. Eddy current damping with rack and gear is supposed to be installed between the building superstructure and foundation to mitigate the seismic response of the building. First, the concept of eddy current damping with rack and gear is introduced in detail and its apparent mass and equivalent damping coefficient are both theoretically investigated. Second, a prototype of eddy current damping with rack and gear is manufactured, and a series of tests on the prototype are carried out to verify its structural parameters. The experimental and theoretical results of the apparent mass of the prototype agree well with each other. The experimental result of the equivalent damping coefficient of the prototype is slightly lower than the numerical results obtained from COMSOL Multiphysics and its maximum relative differences are 11.3% and 13.6% for α = 0° and 45°, respectively. Third, detailed parametric studies on the damping force, including the effects of the thickness of the conductor plate, air gap, and number and location of permanent magnets, are conducted. The results show that the damping force keeps a linear relationship with velocity if it is lower than 0.15 m/s, and with the increase of the velocity, a strong nonlinear relationship between the damping force and the velocity is observed. The available maximum damping force can be increased by decreasing the thickness of the conductor plate and the air gap, increasing the number of permanent magnets. There is an optimal location about the permanent magnets for the available maximum damping force. In addition, the hysteretic curves of the eddy current damping with rack and gear obtained from the test indicate that the ability of energy dissipation is considerable.