bluuebunny/crossref_metadata_2025_split huggingface dataset:
Korelasi Hasil UKG SMA Tahun 2015 dengan Hasil UN Matematika SMA Tahun 2016 Daerah Istimewa Yogyakarta
Authors: Sukardjo Moch , Sugiyanta Lipur 
Published: October 2020

Penelitian ini bertujuan untuk:(1) menghitung kompetensi guru mata pelajaran Matematika tahun 2015 di DIY, (2) menghitung rata-rata nilai UN Matematika tahun 2016, dan (3) menentukan korelasi antara hasil kompetensi guru Matematika tahun 2015 terhadap hasil UN Matematika tahun 2016. Metode yang digunakan adalah deskriptif kuantitatif dengan rumusan korelasi. Data sekunder berasal dari hasil ujian kompetensi guru tahun 2015 Dirjen GTK, Kementerian Pendidikan dan Kebudayaan dan data hasil UN tahun 2016 Pusat Penilaian Pendidikan, Badan Penelitian dan Pengembangan, Kementerian Pendidikan dan Kebudayaan. Populasi seluruh guru Matermatika yang mengikuti UKG tahun 2015 dan seluruh siswa SMA kelas 12 yang mengikuti Ujian Nasional tahun 2016 dan menggunakan sampel jenuh. Hasil analisis regresi menunjukan bahwa nilai UKG Matematika 2015 tidak mempengaruhi perolehan nilai UN Matematika 2016. Hanya 0,03% nilai UN Matematika 2016 yang ditentukan oleh nilai UKG Matematika 2015. Dari hasil tersebut terlihat bahwa UKG Matematika tahun 2015 belum memiliki dampak terhadap peningkatan UN Matematika pada tahun 2016.
Pengembangan Modul Cetak Pembelajaran Remedial Untuk Peningkatan Ketuntasan Belajar Mata Pelajaran Bahasa Indonesia SMP Kelas VIII
Authors: - Supkarwati , Ibrahim Nurdin , - Priyono 
Published: October 2020

Penelitian ini bertujuan untuk menghasilkan modul pembelajaran remedial mata pelajaran Bahasa Indonesia kelas III SMP. Metodologi yang digunakan adalah metologi penelitian pengembangan. Model yang digunakan adalah model Derek Rowntree dengan 3 tahapan, yaitu tahap perencanaan, tahap persiapan penulisan, serta tahap penulisan dan penyuntingan. Hasil penelitian menunjukkan nilai rata-rata dari ahli materi dan bahasa sebesar 3,8. Hal itu menunjukkan bahwa produk yang dihasilkan sangat bagus. Hasil penelitian oleh ahli desain menunjukkan rata-rata 3,7. Artinya, produk ini sangat bagus. Berdasarkan uji satu-satu, hasil rata-rata sebesar 3,7. Artinya, modul ini hasilnya sangat bagus. Dari uji kelompok kecil, nilai rata-rata post test sebesar 82. Ini berarti modul mampu meningkatkan prestasi hasil belajar remedial dengan. Dari ujicoba lapangan, nilai rata-rata post test sebesar 81. Ini berarti, modul mampu meningkatkan prestasi hasil belajar remedial.
Dapat disimpulan bahwa modul cetak pembelajaran remedial bahasa Indonesia untuk siswa kelas VIII SMP dapat dikatakan bagus untuk pembelajaran remedial.
Analysis of Bioavailable Toluene by Using Recombinant Luminescent Bacterial Biosensors with Different Promoters
Authors: Wang Guey-Horng , Tsai Teh-Hua , Kui Chun-Chi , Cheng Chiu-Yu , Huang Tzu-Ling , Chung Ying-Chien 
Published: October 2020

Abstract
In this study, we constructed recombinant luminescent Escherichia coli with T7, T3, and SP6 promoters inserted between tol and lux genes as toluene biosensors and evaluated their sensitivity, selectivity, and specificity for measuring bioavailable toluene in in groundwater and river water. The luminescence intensity of each biosensor depended on temperature, incubation time, ionic strength, and concentrations of toluene and coexisting organic compounds. Toluene induced the highest luminescence intensity in recombinant lux-expressing E. coli with the T7 promoter [T7-lux-E. coli, limit of detection (LOD) = 0.05 μM], followed by that in E. coli with the T3 promoter (T3-lux-E. coli, LOD = 0.2 μM) and SP6 promoter (SP6-lux-E. coli, LOD = 0.5 μM). Luminescence activities may have been synergistically or antagonistically affected by coexisting organic compounds other than toluene; nevertheless, low concentrations of benzoate and toluene analogs had no such effect. In reproducibility experiments, the biosensors had low relative standard deviation (4.3%–5.8%). SP6-lux-E. coli demonstrated high adaptability to environmental interference. T7-lux-E. coli biosensor—with low LOD, wide measurement range (0.05–500 μM), and acceptable deviation (−14.3% to 9.1%)—is an efficient toluene biosensor. This is the first study evaluating recombinant lux E. coli with different promoters for their potential application in toluene measurement in actual water bodies.
Interactive Participatory Audit and Feedback (IPAF): Theory-based development and multi-site implementation outcomes with specialty clinic staff
Authors: Ramly Edmond , Lauver Diane , Gilmore-Bykovskyi Andrea , Bartels Christie M 
Published: October 2020

Abstract
Background: Theory-based implementation strategies, such as audit and feedback (A&F), can improve adoption of evidence-based practices. However, few strategies have been developed and tested to meet the needs of specialty clinics. In particular, frontline staff can execute CVD risk-reduction protocols, but A&F strategies to support them have not been well examined. Our objective was to develop and evaluate a novel A&F strategy, Interactive Participatory A&F (IPAF). Methods: We developed IPAF by combining theories to inform staff goals (Self-Regulation Theory) and address their psychological needs for relatedness, autonomy, and confidence (Self-Determination Theory). We facilitated IPAF fidelity by developing a theory-based facilitation tool: a semi-structured worksheet to guide flexible discussion of target behaviors, perceived barriers, goals, and action plans. We evaluated IPAF in the context of eight quasi-experimental implementations in specialty clinics across two health systems. Following a Hybrid Type 2 effectiveness-implementation design, we reported intervention outcomes for CVD risk-reduction elsewhere. This paper reports implementation outcomes associated with IPAF, focusing on feasibility, acceptability, fidelity, and adoption. We evaluated implementation outcomes using mixed-methods data including Electronic Health Records (EHR) data, team records, IPAF worksheets, and staff questionnaire responses. Results: Eighteen staff participated in 99 monthly, individual, synchronous (face-to-face or by phone) IPAF sessions during the first six months of implementation. Subsequently, we provided over 375 monthly feedback emails. Feasibility data revealed high staff attendance (90-93%) and engagement in IPAF sessions. Staff rated questionnaire items about acceptability of IPAF highly. IPAF records and staff responses demonstrated fidelity of delivery and receipt of IPAF. Adoption of target behaviors increased significantly (all P-values < 0.05) and was maintained for over 24 months. Conclusions: We developed and evaluated an interactive participatory A&F strategy with frontline staff in specialty clinics to improve implementation of evidence-based interventions. The IPAF toolkit combines two complementary theories: Self-Regulation Theory and Self-Determination Theory. Findings support feasibility, acceptability, and fidelity of IPAF, and staff adoption and maintenance of target behaviors. By evaluating multi-site implementation outcomes, we have extended prior research on clinic protocols and A&F beyond primary care settings and providers.
Contribution of root respiration to total soil respiration during non-growing season in mine reclaimed soil with different covering soil thicknesses
Authors: Chen Min , Chen Xiaoyang , Hu Zhiyong , Fan Tingyu , Zhang Shiwen , Liu Ying 
Published: October 2020

Abstract
An accurate assessment of root respiration in mine reclaimed soil is important for effectively evaluating mining area ecosystem. This study investigated dynamic changes in root respiration and contribution of root respiration to total soil respiration (Rr/Rt ratio) during the non-growth season in mine reclaimed soil with different covering soil thicknesses. According to covering soil thicknesses, the study area was divided into four sites: 10-25 cm (site A), 25-45 cm (site B), 45-55 cm (site C) and 55-65 cm (site D). From November 2017 to April 2018 (except February in 2018), the soil respiration, root respiration, temperature at 5 cm, water content and root biomass were measured. The results showed that soil temperature and root respiration exhibited similar diurnal and monthly variations. The root respiration was strongly influenced by soil temperature during the non-growing season, which showed an exponential and positive relationship with soil temperature (P<0.001). The root respiration varied with the covering soil thickness and was the greatest with the covering soil thickness at 25–45 cm. The Rr/Rt ratio also exhibited monthly variations. During the non-growth season, the mean value of the Rr/Rt ratio were 51.15% in mine reclaimed soil. The study indicated that root respiration was the primary source of soil respiration and important to estimate the potential of emission of soil CO 2 at regional scale in mine reclaimed soil.
Chemosensitivity based on pathologic complete response in very young patients with ER-positive breast cancer: a large, multicenter, observational study
Authors: Woo Joohyun , Oh Se Jeong , Song Jeong-Yoon , Chae Byung Joo , Choi Jung Eun , Lee Jeeyeon , Park Heung Kyu , Society Korean Breast Cancer , Lim Woosung 
Published: October 2020

Abstract
Background In estrogen receptor (ER)-positive breast cancer, young age is associated with poor prognosis. Several reports have suggested hormonal mechanism as the possible reason. Conversely, very young patients respond better to chemotherapy, and chemotherapy is less effective in ER-positive tumors than in ER-negative tumors. The authors tried to evaluate the chemoinsensitivity of very young patients with ER-positive breast cancer by pathologic complete response (pCR) after neoadjuvant chemotherapy excluding the effect of endocrine treatment to the extent possible.Methods We collected individual patient data from 1992 to 2013 from the Korean Breast Cancer Society (KBCS). Total 1,048 ER-positive and 797 ER-negative patients aged <50 years who had been treated with neoadjuvant chemotherapy were included for analysis. We compared the pathologic complete response (pCR) rate between patients aged <35 years with ER-positive tumors and the other groups.Results The proportion of very young patient aged <35years was 14% in ER-positive group and 16.8% in ER-negative group. Although most chracteristics of tumors according to age were comparable in both groups, tumors with high Ki-67 expression were more common in patients under 35years of age than in those aged 35-49years in both groups (P = 0.001). Breast conservation rates were not significantly different according to age in two groups (44.2% vs. 46.8% in ER-positive group, 55.2% vs. 48.0% in ER-negative group). pCR rates of both breasts and axilla were not significantly different according to age in ER-positive group (P=0.71) but significantly better in patients aged <35years in ER-negative group (P=0.009). After adjusting for confounding variables, young patients maintained the higher probability of pCR than older patients in ER-negative tumors. However, the pCR rate did not differ according to age in ER-positive tumors. Conclusions Chemotherapy response based on pCR rates was not better in young patients (<35 years) with ER-positive breast cancer than in older premenopausal patients with ER-positive advanced breast cancer. Young age cannot be a predictive factor of chemosensitivity in ER-positive breast cancer. Different biological characteristics such as high Ki-67 proliferative index should be considered.Trial registration: retrospectively registered
In Vitro Study of Biomechanical Analysis of Modified Lateral Lumbar Interbody Fusion—crenel Lumbar Interbody Fusion
Authors: Chen Yun-lin , Lai Ou-jie , Ma Wei-hu , Ma Yu-li , Pang Jia-ni , Chen Qi-xin 
Published: October 2020

Abstract
Background To analyze the biomechanical stability of the modified LLIF, crenel lateral interbody fusion (CLIF), and compare various methods of instrumentation of CLIF in vitro.Methods Three fresh-frozen cadaveric lumbar spines (L1-S1) were used in our study. The modified CLIF interbody cage was inserted into the L3/4 level in each specimen. Every specimen was tested under 5 conditions: intact group; stand-alone CLIF group; CLIF with lateral plate group (CLIF + LP); CLIF with lateral plate and unilateral pedicle screw group (CLIF + LP + UPS); CLIF with bilateral pedicle screw group (CLIF + BPS).Results The ROM of each CLIF group was significantly reduced when compared with intact group in all directions of loading (p< 0.05). The CLIF + LP + BPS group was the most stable in all directions of loading. CLIF + LP group has less ROM when compared with stand-alone group except for the extension condition. CLIF + BPS group has less ROM than CLIF + LP group in every condition. Conclusions CLIF combine with lateral plate and bilateral pedicel screw is the most stable supplemental fixation, and lateral plate could reduce the ROM under rotation and lateral bending conditions. For patients with good bone quality, stand-alone with or without is a alternative method to achieve a good clinical result.
Identification and characterization of circRNAs in the deposition of intramuscular fat in Aohan fine-wool sheep
Authors: Zhao Le , Liu Nan , Han Fuhui , Zhou Lisheng , Liu Lirong , Wang Lei , Zhao Ranran , Duan Xinming , He Jianning 
Published: October 2020

Abstract
Background

Aohan fine-wool sheep (AFWS) is a high-quality fine-wool sheep breed that supplies both wool and meat. The quality of its meat is affected by many factors. Research is needed on the molecular mechanism of intramuscular fat (IMF) growth, which greatly improves mutton quality. The widely expressed non-coding RNA is used in roles such as competitive endogenous RNAs (ceRNAs), including microRNAs (miRNAs). Although circular RNA (circRNA) was studied in many fields, little research was devoted to IMF in sheep. We used RNA-Seq to analyze tissues associated with IMF in 2-month-old and 12-month-old AFWS rams to understand the role of circRNA in the growth and development of sheep IMF.
Results

A total of 11,565 candidate circRNAs were identified, of which 104 were differentially expressed in the two age groups. We analyzed these differentially expressed circRNAs. Enrichment analysis was performed using Gene Ontology and the Kyoto Encyclopedia of Genes and Genomes. The enriched pathways included lipid transport (GO:0006869), negative regulation of canonical Wnt signaling pathway (GO:0090090), fat digestion and absorption (ko04975), and sphingolipid metabolism (ko00600). We used the TargetScan and miRanda software programs for interaction analysis, and a network diagram was created. Six circRNAs were randomly selected and verified the RNA-Seq results by quantitative real-time PCR.
Conclusion

This study provides more information on circRNA regulation in AFWS, and is a useful resource for further research on this sheep breed.
Pharmacodynamics of efavirenz 400mg in treatment-naïve Chinese HIV-infected patients in a prospective cohort study
Authors: Xu Ling , Peng Wenxiu , Song Xiaojing , Li Yanling , Han Yang , Zhu Ting , Fu Qiang , Du Xiaoli , Cao Wei , Li Tai-Sheng 
Published: October 2020

Abstract
BackgroundThe plasma concentration of efavirenz (EFV) 600mg dose was found to exceed the upper limit of proposed therapeutic window in most Chinese HIV-infected individuals, thus dosage reduction of EFV to 400mg daily warrant consideration. This study aimed at assessing the pharmacodynamics of EFV 400mg for HIV-infected patients in China. MethodTwenty cART-naïve individuals were enrolled in this study. EFV 400mg combined with tenofovir (TDF) and lamivudine (3TC) as initial antiretroviral regimens were administered for 48 weeks. EFV concentration and T-cell subsets as well as HIV RNA load were evaluated at baseline, 4, 12, 24, 48 weeks. Moreover, the neuropsychiatric adverse effects were also assessed by Hamilton depression scale (HAMD) and Pittsburgh sleep quality index (PSQI).ResultsEighteen males and two females whose median age was 26 (interquartile range [IQR]: 23-32) years completed 48 weeks of follow-up. The median EFV concentration was 1.88 (IQR: 1.54-2.42), 1.74 (IQR: 1.36-1.93), 1.93 (IQR: 1.66-2.22), 1.85 (IQR: 1.54-2.14) mg/L at week 4, 12, 24, 48, respectively. The viral load was 4.59 (IQR: 4.10-5.19) lg copies/mL at baseline and it decreased by 4.6 (IQR: 3.98-5.18) lg copies/mL from baseline to weeks 48. 3 of 20 (15%), 10 of 20 (50.0%), 17 of 20 (85%), 18 of 19 (95%) participants had a plasma viral load less than 50 copies/mL at weeks 4, 12, 24, 48 respectively. The median CD4 cell count was 330 (IQR: 237-410) cells/µL at baseline and it increased to 473 (IQR: 344-574) cells/µL at 48 weeks. The score of HAMD was 5 (IQR: 3-9.8), 3 (IQR: 2.25-4) at baseline and 48 weeks. And the score of PSQI was 4 (IQR: 2-5.8), 3 (IQR: 2-4) at baseline and 48 weeks. Dizziness was the most common event, occurring in 70% patients within the first two weeks of treatment. ConclusionPatients prescribed with EFV 400mg-containing agents demonstrated favorable virological and immunological responses. And the plasma EFV concentration was within the recommended therapeutic range with less adverse reactions. EFV 400mg was effective and safe in Chinese HIV-infected patients.
Evaluating the Implementation of a Pragmatic Person-Centered Communication Tool in the Nursing Home via the RE-AIM Framework.
Authors: Abbott Katherine , Heppner Alexandra , Hicks Nytasia , Hermesch Abigail , VanHaitsma Kimberly 
Published: October 2020

Abstract
Background: Person-centered care (PCC) is a philosophy that recognizes “knowing the person” and honoring individual preferences. The purpose of this study was to evaluate the implementation of a novel PCC communication tool in nursing homes (NH). The tool is based on an assessment of NH resident likes and dislikes via the Preferences for Everyday Living Inventory (PELI), which is an evidenced-based, validated instrument used to enhance the delivery of PCC. The Preferences for Activity and Leisure (PAL) Card was developed to communicate residents’ preferences for leisure and activities across care team members. Methods: Providers were recruited to utilize the recreation and leisure items from the PELI to assess resident important preferences and create PAL Cards for 15-20 residents. Providers collected data aligned with the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, Maintenance). Results: Reach and Adoption: A total of n=43 providers registered and n=26 (60%) providers completed the project. Ownership of participating providers included 54% not for profit, 46% for profit, and 8% government owned with an average star rating of 3.7 (SD 1.1) and a range of 1-5. Effectiveness and Implementation: Participants attempted n=424 PAL Cards and completed n=406. The average acceptability of the intervention measure (AIM) was 4.7 (SD 0.4), intervention appropriateness measure (IAM) was 4.5 (SD 0.5), and feasibility of intervention measure (FIM) was 4.6 (SD 0.5). Maintenance: Providers were able to complete 82% of PAL Card placement over the course of 5 months with few cards going missing (<2%). Conclusion: The majority of providers were successful in implementing PAL Cards for residents and reported the intervention as highly acceptable, appropriate, and feasible. The pragmatic PAL Card intervention can assist nursing home providers in meeting PCC regulations and contribute to building relationships between residents, family, and staff.
A Turbulence Scaling Factor that converts laminar solutions to turbulent solutions
Authors: Onur Huseyin 
Published: October 2020

Abstract
The quest to understand turbulent flows continues to be as important as it was during the previous century.
Present work shows that if a 'laminar' solution to Navier -Stokes equations can be found then skin friction and heat transfer coefficients for the turbulent case can readily be obtained. There is no need for Reynolds averaging and turbulence modelling.
This can be done by defining a turbulence scaling factor which converts 'laminar' diffusivities to turbulent diffusivities. Using turbulent diffusivities in the laminar skin friction coefficient formula and laminar heat transfer coefficient formula gives the corresponding turbulent formula.
Five different test cases with credible experimental measurements have been used to show the success of the present approach. This work also gives the lengths of internally generated turbulent eddies and roughness created
turbulent eddies. If main flow mixes the turbulent eddies , smaller eddies are merged by the larger ones and this is the suggested model for roughness effects which dominates at large Reynolds numbers. A single effective roughness which determines the friction factor has also been obtained and the fractal dimension of turbulence is given as power to Reynolds number. This fractal dimension is in accord with literature for turbulent/non-turbulent interfaces.
Inflammatory Myofibroblastoma Tumor of Intraocular Ciliary Body: A Case Report and Literature Review
Authors: yu he , Tong Nianting , Huang Weiqing , Zhou Zhan Yu 
Published: October 2020

Abstract
Background: IMTs are extremely rare in eyes. This is the first report of a IMT of the ciliary body.Case presentation: A ciliary body tumor was found under slit lamp biomicroscopy in a 55-year-old male first diagnosed with cataract. Then this patient underwent trans-sclera resection via partial lamellar sclerouvectomy and par plans vitrectomy to remove the mass. Hematoxylin and eosin (HE) staining and immunohistochemistry findings showed that the characteristics of the tumor were consistent with inflammatory myofibroblastoma tumor (IMT).Conclusions: we reported a rare case of intraocular IMT, which is confirmed by H&E staining, and IHC positive staining for Vimentin, Desmin and ALK, while negative staining for SMA, S-100, ki-67, CK, CD68, and calponin.
Habitual Tea Consumption and 5-year Incident Metabolic Syndrome Among Older Adults: A Community-based Cohort Study
Authors: liu jieyu , Wang Ruirui , Liu Jinghong , Ma Qinghua , Xu Yong , Pan Chenwei 
Published: October 2020

Abstract
Background: The effect of tea consumption on metabolic syndrome (MetS) remains controversial. The objective of this study is to examine the prospective association of tea consumption with 5-year incident MetS among aged population in China.Methods: This analysis included 3005 Chinese adults aged 60 years or older who were free of MetS at baseline examination. MetS was defined according to the National Cholesterol Education Program-Adult Treatment Panel III. Information regarding tea consumption was collected via an interviewer-administrated questionnaire. The prospective associations between tea consumption at baseline and 5-year incident MetS, as well as its individual components, were assessed by multiple logistic regression models.Results: In multiple logistic regressions, habitual drinkers had a 34% increased risk of developing MetS during the 5-year follow-up period compared with non-habitual drinkers. Correspondingly, 5-year cumulative incidence of MetS was found to be higher in those who drank tea more than 5 times per week as compared with non-habitual drinkers. Among the five major components of MetS, low high-density lipoprotein cholesterol was observed in men, while high body mass index, elevated blood pressure and the presence of diabetes mellitus were significant in women.Conclusions: Habitual tea consumption increased the risk of MetS among older Chinese adults. These findings may add novel knowledge to the current studies regarding the controversial effect of tea consumption on cardiovascular and metabolic health among the aged population.