bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long‐eccentricity regulated climate control on fluvial incision and aggradation in the Palaeocene of north‐eastern Montana (USA)
Authors: Noorbergen Lars J. , Turtu Antonio , Kuiper Klaudia F. , Kasse Cornelis , van Ginneken Sverre , Dekkers Mark J. , Krijgsman Wout , Abels Hemmo A. , Hilgen Frederik J. 
Published: January 2020

AbstractAggradation and fluvial incision controlled by downstream base‐level changes at timescales of 10 to 500 kyr is incorporated in classic sequence stratigraphic models. However, upstream climate control on sediment supply and discharge variability causes fluvial incision and aggradation as well. Orbital forcing often regulates climate change at 10 to 500 kyr timescales while tectonic processes such as flexural (un)loading exert a dominant control at timescales longer than 500 kyr. It remains challenging to attribute fluvial incision and aggradation to upstream or downstream processes or disentangle allogenic from autogenic forcing, because time control is mostly limited in fluvial successions. The Palaeocene outcrops of the fluvial Lebo Shale Member in north‐eastern Montana (Williston Basin, USA) constitute an exception. This study uses a distinctive tephra layer and two geomagnetic polarity reversals to create a 15 km long chronostratigraphic framework based on the correlation of twelve sections. Three aggradation–incision sequences are identified with durations of approximately 400 kyr, suggesting a relation with long‐eccentricity. This age control further reveals that incision occurred during the approach of – or during – a 405 kyr long‐eccentricity minimum. A long‐term relaxation of the hydrological cycle related to such an orbital phasing potentially exerts an upstream climate control on river incision. Upstream, an expanding vegetation cover is expected because of an increasingly constant moisture supply to source areas. Entrapping by vegetation led to a significantly reduced sediment supply relative to discharge, especially at times of low evapotranspiration. Hence, high discharges resulted in incision. This study assesses the long‐eccentricity regulated climate control on fluvial aggradation and incision in a new aggradation–incision sequence model.
Does stress transmission in forelands depend on structural style? Distinctive stress magnitudes during Sevier thin‐skinned and Laramide thick‐skinned layer‐parallel shortening in the Bighorn Basin (USA) revealed by stylolite and calcite twinning paleopiezometry
Authors: Beaudoin Nicolas , Lacombe Olivier , David Marie‐Eléonore , Koehn Daniel 
Published: January 2020

AbstractThe Sheep Mountain‐Little Sheep Mountain Anticlines, Bighorn Basin (USA) formed as basement‐cored Laramide structures in the formerly undeformed foreland of the thin‐skinned Sevier orogen. We take advantage of the well‐constrained microstructural network there to reconstruct differential stress magnitudes that prevailed during both Sevier and Laramide layer‐parallel shortening (LPS), before the onset of large‐scale folding. Differential stress magnitudes determined from tectonic stylolites are compared and combined to previous stress estimates from calcite twinning paleopiezometry in the same formations. During stress loading related to LPS, differential stress magnitudes transmitted from the distant Sevier thin‐skinned orogen into the sedimentary cover of the Bighorn basin (11–43 MPa) are higher than the differential stress magnitudes accompanying the early stage of LPS related to the thick‐skinned Laramide deformation (2–19 MPa). This study illustrates that the tectonic style of an orogen affects the transmission of early orogenic stress into the stable continental interior.
Detection of Felis catus papillomavirus type‐2 DNA and viral gene expression suggest active infection in feline oral squamous cell carcinoma
Authors: Altamura Gennaro , Cardeti Giusy , Cersini Antonella , Eleni Claudia , Cocumelli Cristiano , Bartolomé del Pino Leticia Elisa , Razzuoli Elisabetta , Martano Manuela , Maiolino Paola , Borzacchiello Giuseppe 
Published: January 2020

AbstractPapillomavirus (PV) infection is associated with development of epithelial cancer in different species, including domestic cat (Felis catus). Felis catus PV type‐2 (FcaPV‐2) is considered the causative agent of a proportion of feline cutaneous squamous cell carcinoma (SCC), through the transforming properties of its E6 and E7 oncogenes. However, the possible role of FcaPVs in the aetiology of feline oral SCC (FOSCC) is still unclear. The aim of this study was to assess the presence and gene expression of FcaPV‐2 in FOSCC samples. We detected FcaPV‐2 DNA in 10/32 (31%) of the analysed FOSCC by the use of PCR methods. Importantly, viral mRNA was detected by RT‐PCR in 7/10 (70%) of DNA positive samples. In particular, FcaPV‐2 L1, E2 and E6E7 genes were found to be expressed in 5/10 (50%), 3/10 (33%) and 5/10 (50%) samples, respectively. Viral DNA was also detected in non neoplastic oral ulcerative lesions (ULs) (4/11, 36%); qPCR suggested a difference in viral load between ULs and FOSCCs, particularly in those expressing E6E7, although it was not statistically significant. These data suggest, but do not definively prove, a possible role of FcaPV‐2 in the development of a proportion of FOSCC. Moreover, L1 and E2 gene expression results indicate that FcaPV‐2 infection associated with these tumours may possibly be productive.
Percepciones de los estudiantes de primer semestre de Medicina de sus actitudes académicas frente al curso de anatomía
Authors: Ruiz Fabio Enrique , Cortés Michelle 
Published: January 2020

Introducción. El curso de anatomía de la carrera de Medicina de la Pontificia Universidad Javeriana ofrece una metodología basada en el aprendizaje cooperativo. Para valorar las distintas actividades de dedicación personal y estudio de los estudiantes, se diseñó una autoevaluación dirigida de sus percepciones sobre sus propias actitudes con respecto al curso.
Uso de la mamografía de tamizaje en las pacientes con diagnóstico con cáncer de seno en el Hospital Universitario San Ignacio, Centro Javeriano de Oncología
Authors: Angarita Fernando Andrés , Acuña Sergio Andrés , Tawil Mauricio , Ruiz Álvaro J. , Torregosa Liliana 
Published: January 2020

Introducción. Actualmente el cáncer de seno ha logrado trascender en la salud de las mujeres colombianas, por ser una enfermedad con alta mortalidad. Hoy por hoy, se ofrece tamizaje de oportunidad con mamografía para mujeres mayores de 50 años, pero aún es escasa la información sobre cómo se están detectando los nuevos casos en Colombia.
El modelo de la complejidad frente a los modelos psicológicos tradicionales de la ansiedad ante la muerte
Authors: Álvarez Leonardo Yovany 
Published: January 2020

El tema de la ansiedad ante la muerte ha sido objeto de investigación desde diferentes perspectivas psicológicas, hace parte de muchos cursos de tanatología para estudiantes delárea de la salud y, también, de algunos cursos para operadores encargados de trabajar con pacientes terminales. La ansiedad ante la muerte es un fenómeno complejo que involucra las capacidades de afrontamiento del individuo pero a su vez implica la confrontación de la experiencia vital, la integración de la misma, la resolución de expectativas, el duelo, en un momento que se torna implacable. En la presente revisión sobre la ansiedad ante la muerte, se analizan algunos de los modelos psicológicos individualistas, vinculares y psicosociales. Se discuten los alcances y limitaciones de la perspectiva explicativa unidireccional de laansiedad ante la muerte desde la cual se la aprecia como un evento generador de defensa psicológica y de reacciones de evitación, ya sea mediante la postergación, la atribuciónexterna, la búsqueda de la plenitud en la individuación dejando de lado las contradicciones, ambigüedades, borrosidades y ambivalencias que dicho fenómeno psicológico tiene, lo cual deriva variadas implicaciones para su comprensión e intervención no sólo dentro de la institución sanitaria sino desde el ámbito social y comunitario.
Telemedicina: historia, aplicaciones y nuevas herramientas en el aprendizaje
Authors: Cáceres-Méndez Edward A. , Castro-Díaz Sergio M. , Gómez-Restrepo Carlos , Puyuna Juan Carlos 
Published: January 2020

Introducción: En la actualidad las intervenciones en salud ya sean de tipo diagnóstico o terapéutico no son distribuidas equitativamente, por lo cual garantizar la prestación de servicios de salud representa un reto incesante para muchos programas en diferentes países; sin embargo, gracias a los avances tecnológicos en telecomunicación y procesos de imágenes, es ahora posible ofrecer varios servicios de salud a un mayor número de la población a distancia con un buen nivel de calidad; esto se define como telemedicina.Método: A través de una búsqueda sistemática de la literatura médica en las bases de datos: Medline, ieeexplore, Scielo, por medio de las palabras mesh: Medical informatics, technology management, telemedicine, E-health, Latinoamérica, se buscó reconocer los datos relevantes con respecto a la historia, las aplicaciones actuales y futuras de la telemedicina.Desarrollo: Después de seleccionar la mejor evidencia según los objetivos de esta revisión, se procedió a analizar la importancia de la historia, aplicaciones en especialidades de medicina, ventajas y desventajas, barreras que limiten el desarrollo, y experiencias de la telemedicina en Latinoamérica.Conclusión: Actualmente el uso de la telemedicina avanza rápidamente y podría representar una buena alternativa para complementar en términosde costo-efectividad a muchos de los programas de salud que se ven alrededor del mundo, ya que facilita la toma de decisiones terapéuticas y diagnósticas en diferentes escenarios clínicos y complementa la formación académica en las escuelas de medicina; sin embargo, aun existen barreras de infraestructura principalmente los altos costos de inicio e instalación, que deben ser tenidos en cuenta, en especial para los países en desarrollo.
Endarterectomía carotídea en octogenarios: comparación de desenlaces con pacientes menores de 80 años, experiencia en la Fundación Cardio Infantil
Authors: Monroy Melo Fernando , Cepeda Páez Katerine Andrea , Camacho Mackenzie Jaime , Pinzón Flórez Carlos Eduardo 
Published: January 2020

Introducción. Dado el incremento de los pacientes con edades superiores a los 80 años que son llevados a cirugía cada año en nuestra institución, consideramos importante conocer el comportamiento en términos de morbilidad y mortalidad tempranas de los pacientes octogenarios sometidos a endarterectomía carotídea.Objetivo. Evaluar los resultados a 30 días de pacientes octogenarios con enfermedad carotídea grave, sintomática y asintomática, sometidos a endarterectomía carotídea, comparados con una cohorte histórica de pacientes de menor edad operados desde 1995 en la Fundación Cardio Infantil. Se registraron como variables dependientes la mortalidad y el accidente cerebrovascular.Resultados. Se registraron 218 endarterectomías carotídeas, 189 (86,6%) en pacientes menores de 80 años y 30 (13,4%) en pacientes octogenarios. En pacientes octogenarios no se presentaron accidentes cerebrovasculares (0%) y la mortalidad fue de 3,3%. En el grupo de pacientes menores de 80 años se presentaron accidentes cerebrovasculares (1,7%) y muerte (1,1%). Conclusiones. Los pacientes octogenarios con adecuada funcionalidad y sin contraindicaciones claras pueden ser sometidos a endarterectomía carotídea de manera segura.
Neurocirugía ablativa estereotáctica en las adicciones
Authors: Castaño Juliana , Díaz María Virginia 
Published: January 2020

El tema de la neurocirugía ablativa para las adicciones ha sido objeto de investigación desde diferentes perspectivas, tanto en su aspecto neurofisiológico como psiquiátrico. Los nuevos datos y conocimientos han demostrado la gran importancia de las conexiones entre las diferentes áreas del cerebro, cuya actividad uncional se altera durante el desarrollo del fenómeno adictivo; por eso, es importante vincular el conocimiento anatómico y neurofisiológico del sistema mesolímbico para desarrollar técnicas quirúrgicas como métodos curativos o paliativos para las adicciones.En la presente revisión sobre la neurocirugía ablativa para las adicciones, se analizan la anatomía y la neurofisiología del sistema límbico, particularmente del núcleo accumbens, y se discuten los alcances y las limitaciones de las técnicas quirúrgicas actuales, las cuales deben tenerse en cuenta para futuros avances en el campo neuroquirúrgico.
Predictors of neonatal mortality: development and validation of prognostic models using prospective data from rural Bangladesh
Authors: Khan Farhad A , Mullany Luke C , Wu Lee F-S , Ali Hasmot , Shaikh Saijuddin , Alland Kelsey , West Jr Keith P , Labrique Alain B 
Published: January 2020

ObjectiveTo assess the extent to which maternal histories of newborn danger signs independently or combined with birth weight and/or gestational age (GA) can capture and/or predict postsecond day (age>48 hours) neonatal death.MethodsData from a cluster-randomised trial conducted in rural Bangladesh were split into development and validation sets. The prompted recall of danger signs and birth weight measurements were collected within 48 hours postchildbirth. Maternally recalled danger signs included cyanosis (any part of the infant’s body was blue at birth), non-cephalic presentation (part other than head came out first at birth), lethargy (weak or no arm/leg movement and/or cry at birth), trouble suckling (infant unable to suckle/feed normally in the 2 days after birth or before death, collected 1-month postpartum or from verbal autopsy). Last menstrual period was collected at maternal enrolment early in pregnancy. Singleton newborns surviving 2 days past childbirth were eligible for analysis. Prognostic multivariable models were developed and internally validated.ResultsRecalling ≥1 sign of lethargy, cyanosis, non-cephalic presentation or trouble suckling identified postsecond day neonatal death with 65.3% sensitivity, 60.8% specificity, 2.1% positive predictive value (PPV) and 99.3% negative predictive value (NPV) in the development set. Requiring either lethargy or weight <2.5 kg identified 89.1% of deaths (at 39.7% specificity, 1.9% PPV and 99.6% NPV) while lethargy or preterm birth (<37 weeks) captured 81.0% of deaths (at 53.6% specificity, 2.3% PPV and 99.5% NPV). A simplified model (birth weight, GA, lethargy, cyanosis, non-cephalic presentation and trouble suckling) predicted death with good discrimination (validation area under the receiver-operator characteristic curve (AUC) 0.80, 95% CI 0.73 to 0.87). A further simplified model (GA, non-cephalic presentation, lethargy, trouble suckling) predicted death with moderate discrimination (validation AUC 0.74, 95% CI 0.66 to 0.81).ConclusionMaternally recalled danger signs, coupled to either birth weight or GA, can predict and capture postsecond day neonatal death with high discrimination and sensitivity.
Effect of knee extensor fatigue level and sex on bilateral jump-landing
Authors: Noh Byungjoo , Youm Chang Hong , Lee Myeounggon , Park Hwayoung , Son Minji , Kim Jinhee 
Published: January 2020

ObjectiveThe purpose of this study was to determine the effect of fatigue level and sex on the range of motions of the lower extremities and impulses during the jump-landing phase after performing bilateral fatiguing tasks.MethodsIn total, 41 healthy young adults volunteered for this study. Participants’ jump-landing trajectories were monitored using nine cameras, and ground reaction forces were measured using a force plate. Participants performed five maximal bilateral countermovement jumps as prefatiguing tasks. The fatiguing tasks consisted of maximal effort contractions of the knee extensor at 60°/s on a dynamometer until task failure, defined as the inability to reach 50% of the peak knee extension torque for three consecutive times. The post-task maximal bilateral jumps were immediately captured after the participants failed the fatiguing task. Participants were asked to perform this cycle again, performing the fatiguing contraction task until failure to reach 30% of the peak knee extension torque.Results and conclusionIt was found that the knee joint was more extended in the post-30% fatiguing task, which was due to the reduction of the flexion angle of the hip and knee joints in response to fatigue level. The impulses for both sexes were reduced at the severe fatigue level. Fatigability altered jump-landing kinematics, jump heights and impulses in response to fatigue level. The post-30% fatiguing task elicited more fatigue than the post-50% fatiguing task.
Determining the role of sport coaches in promoting athlete mental health: a narrative review and Delphi approach
Authors: Bissett James E. , Kroshus Emily , Hebard Stephen 
Published: January 2020

BackgroundCoaches have the potential to support athlete mental wellness, but many are unsure what to do and concerned they may unintentionally engage in behaviours that negatively impact their athletes. Education has the potential to help coaches engage in primary, secondary and tertiary preventive behaviours related to athlete mental health; however, there exists no empirical or consensus basis for specifying the target behaviours that should be included in such education.ObjectiveThe aim of this research was to review extant literature about the role of sport coaches in mental health prevention and promotion, and obtain expert consensus about useful, appropriate and feasible coach behaviours.DesignModified Delphi methodology with exploration (ie, narrative review) and evaluation phase.Data sourcesTwenty-one articles from PubMed, PsycINFO and ProQuest, and grey literature published by prominent sport organisations.Eligibility criteria for selecting studiesAll studies were English-language articles that focused on the role of coaches as they relate to (1) culture setting in sport, (2) addressing athlete mental health and (3) providing ongoing support to athletes with mental health concerns. No study design, publication date limits or sport characteristics were applied.ResultsThe coach’s role should include fostering team cultures that support athlete mental health, encouraging care-seeking and supporting athletes currently receiving mental healthcare.Summary/ConclusionThe behaviours specified herein have implications for coach education programme development. This study is the first to use a structured Delphi process to develop specific recommendations about the role coaches can play in supporting athlete mental health.
A retrospective cohort study on the provision and outcomes of pharmacological therapy after revascularisation for peripheral arterial occlusive disease: a study protocol
Authors: Peters Frederik , Kreutzburg Thea , Kuchenbecker Jenny , Debus Sebastian , Marschall Ursula , L'Hoest Helmut , Behrendt Christian-Alexander 
Published: January 2020

BackgroundSymptomatic peripheral arterial occlusive disease (PAOD) involves highly complex and costly revascularisations for preventing adverse limb events and impaired survival. Contrary to recommendations from valid guidelines, a large group of patients do not receive adequate pharmacological therapy after such interventions. Based on health insurance claims data, our study aims to assess (1) the extent of provision of pharmacological therapy after revascularisation and (2) related long-term outcomes for all patients and subgroups, that is, gender and disease severity.MethodsA retrospective observational population-based cohort study will be based on data from the second largest statutory health insurance fund in Germany (BARMER) covering about 13% of the insured population (~10 million patients). Study entry is the index revascularisation for symptomatic PAOD. Study variables will be analysed and compared among subgroups using parametric and non-parametric tests, generalised linear regression analysis and survival models.DiscussionThis study will provide a comprehensive insight in the extent and time trends of adequate provision of pharmacological therapy and long-term outcomes for patients with symptomatic PAOD. This may help to identify those patients benefiting most from improved pharmacological therapy for increasing the success of revascularisations in general.Trial registrationNCT03909022.
Attitudes to ageing, biomarkers of ageing and mortality: the Lothian Birth Cohort 1936
Authors: McLachlan Kyle J J , Cole James H , Harris Sarah E , Marioni Riccardo E , Deary Ian J , Gale Catharine R 
Published: January 2020

ObjectiveTo investigate whether people with more positive attitudes to ageing are biologically younger as defined by leucocyte telomere length, accelerated DNA methylation GrimAge (AgeAccelGrim) and brain-predicted age difference, and whether these biomarkers explain relationships between attitudes to ageing and mortality.MethodsWe used linear regression to examine cross-sectionally attitudes to ageing (measured using the Attitudes to Ageing Questionnaire) and the three biomarkers in 758 adults, mean age 72.5 years, from the Lothian Birth Cohort 1936. We used Cox proportional hazards models to examine longitudinally attitudes to ageing and mortality and the role of the biomarkers.ResultsMore positive attitude to physical change was associated with younger biological age, as measured by AgeAccelGrim and brain-predicted age difference in age-adjusted and sex-adjusted models: for an SD higher score, AgeAccelGrim was lower by -0.73 (95% CI -1.03 to -0.42) of a year, and brain-predicted age difference was lower by -0.87 (1.51 to 0.23) of a year. Both associations were attenuated by adjustment for covariates and not significant after simultaneous adjustment for all covariates and correction for multiple testing. More positive attitudes to physical change were associated with lower mortality: for an SD higher score the age-adjusted and sex-adjusted HR (95% CI) was 0.66 (0.56 to 0.78). Adjustment for AgeAccelGrim or brain-predicted age difference attenuated this association slightly. It remained significant after adjustment for all covariates.ConclusionWe found partial evidence that attitudes to ageing are linked with ageing biomarkers but they accounted for only a little of the association between attitudes and mortality.
SIGecom job market candidate profiles 2020
Authors: Gkatzelis Vasilis , Hartline Jason 
Published: January 2020

This is the fifth annual collection of profiles of the junior faculty job market candidates of the SIGecom community. The seventeen candidates for 2020 are listed alphabetically and indexed by research areas that define the interests of the community. Along with information regarding the candidate's bio, research summary, and representative papers, each profile also contains links to the candidate's homepage, CV, and Google scholar publication profile.
Employers with a relevant job opening can reach all the listed candidates directly by sending the relevant information to the moderated mailing list ecom-candidates2020@acm.org.