bluuebunny/crossref_metadata_2025_split huggingface dataset:
STRATEGI KEPEMIMPINAN KEPALA SEKOLAH DALAM PENGEMBANGAN KOMPETENSI PROFESIONAL GURU UNTUK PENINGKATKAN MUTU PENDIDIKAN DI SMK CENDIKIA MUSLIM KABUPATEN BOGOR
Authors: Awaludin Awaludin 
Published: August 2020

ABSTRACT
This study to provide an overview of the leadership of school principle in the development of professional competence and teacher for improving the quality of eduation in Cendikia Muslim Vocational School Bogor, which is explained in depth, the procedures and concrete steps of the principal’s leadership in developing professional competence to improve the quality of education in the Cendikia Muslim Vocational School in Bogor as well as in factors and supporting the role of the principal’s leadership in developing the professional competence of teachers in the Cendikia Muslim Vocational School in Bogor. This research is a form of field research that is descriptive qualitative, using several approaches namely, pedagogical, sosiological, psychological and managerial. The author also uses several instruments to including observation, documentation, and interviews. The type of data needed in this study are primary data and secondary of teachers to improvedata. While the data collection techniques used are observation, interviews, and documentation referring to the deductive and inductive analysis using several methods that are relevant to the main variables to be studied, while the informant as the resource person is the principal, the teacher. Based on this research it can be concluded that the Principal's Strategy and Leadership in developing professional competence of teachers to improve the quality of education that the leadership of the Head of the Bogor Cendikia Muslim Vocational School in carrying out their duties responsibly, to improve teacher competency and professionalism, by conducting a normative approach or providing motivation teachers to always work in accordance with their duties, with expertise in the field of study being taught. The procedure desired by the principal in improving teacher competency and professionalism is to supervise the deliberation, communication, planning, coordination and evaluation approach, with this application finally all intentions will be realized. To overcome the inhibiting factors in the implementation of education, especially the success of school principals in improving teacher competency and professionalism, it is expected that the unity of steps and togetherness of the goals of all school components including headmasters, teachers, students, and parents and the surrounding community will jointly implement their vision and mission at Cendikia Muslim Vocational School Bogor
Keywords: Leadership and Principal Strategies and Teacher Professional Competence
PEMBELAJARAN EKONOMI EFEKTIF DI MADRASAH ALIYAH SAHID
Authors: Purba Asnan , Maturidi Maturidi 
Published: August 2020

ABSTRACT
This study aims to explore ways of effective economic learning in Madrasah Aliyah Sahid, given the importance of effective learning to produce outputs that are expected in accordance with the expectations of Madrasah Aliyah Sahid. In this study the researchers tried to find what steps were taken by the teacher to create effective learning specifically economic lessons both from the methods used by the teacher, the learning model how it was implemented in MA Sahid and how the evaluation was carried out at this institution, and the driving factors, inhibiting factors in effective economic learning activities at Madrasah Aliyah Sahid.
Keywords: economics, learning, effective, madrasa
INDEKS MASLAHAT SEBAGAI INDIKATOR ALTERNATIF KEBERHASILAN PEMBANGUNAN
Authors: Junaedi Dedi 
Published: August 2020

ABSTRACT
The main objective of a country's economic development is an effort to improve the welfare of its people. Various indicators of development success have been offered. Starting from GDP and per capita income, human development index (HDI), people's welfare index (pledge) and economic welfare index (Eurostat). In the perspective of Islam, the various indicators still have weaknesses because they only display worldly statistics, they have not touched the aspect of ukhrawi (afterlife). On that basis, Islam introduced the concept of maqasid al-shariah or benefit as an indicator of the success of development. The benefit to be achieved includes the safeguarding of five basic elements of human life: faith (monotheism), soul, reason, descent, and wealth (wealth). From these five elements we can develop a number of benefit parameters as indicators of complete human development.
Keywords: eurostat, ikrar, HDI, benefits, maqasid al-sharia, GDP
Rekenmethodiek overlijdensschade nieuwe stijl compleet
Authors: de Koning C.C.J. , Laumen-de Valk J. 
Published: August 2020

Rekenmethodiek overlijdensschade nieuwe stijl compleet
Nadat in 2014 de eerste versie van de rekenmethodiek overlijdensschade door de Denktank was opgeleverd, heeft De Letselschade Raad de aanbevelingen van de Denktank Overlijdensschade overgenomen en verwerkt in De Letselschade Richtlijn Rekenmodel Overlijdensschade 2015. In 2019 is de Denktank 2.0 verdergegaan met de uitbreiding van het rekenmodel voor andere gezinnen dan het traditionele tweeoudergezin. In maart 2020 is de Richtlijn Rekenmodel Overlijdensschade hierop aangepast.
Larvicidal Activity of Some Plants Extracts and Their Partitioned Fractions against Culex quinquefasciatus
Authors: Famuyiwa Funmilayo G. , Adewoyin Francis B. , Oladiran Oluyemi J. , Obagbemi Oluwatosin R. 
Published: August 2020

Aim: The methanol extracts of fifteen plants and their partitioned fractions were screened for larvicidal activity against the fourth instar of larvae Culex quinquefasciatus, the vector of lymphatic filariasis with a view to identifying the active ones.
Methodology: The plant parts were collected, separately dried and milled. Each powdered material was extracted in methanol at room temperature for 3 days, with agitation. The extract was filtered and concentrated in vacuo. Each extract was tested against the fourth instar larvae of Cx. quinquefasciatus. The methanol extracts were suspended in water and successively partitioned into n-hexane and ethylacetate. Each partitioned fraction was also tested against the fourth instar larvae of Cx. quinquefasciatus.
Results: About fifty six percent (56.3%) of the tested extracts had moderate larvicidal activity after 48 hours. The fruit extract of Thevetia neriifolia and the leaf extracts of Calotropis procera and Solanum macrocarpon were the most active. After partitioning the methanol extracts, each of the plant extracts had one or two highly active partitioned fractions after 48 hours. The n-hexane fractions of S. macrocarpon (0.78 ± 0.03 mg/mL) and Spondias mombin (0.81 ± 0.03 mg/mL) were the most active.
Conclusion: The non-polar fractions of S. macrocarpon and S. mombin were the most active. Purification of these highly active fractions could lead to the isolation of potent larvicidal compounds that could be used in the control of Cx. quinquefasciatus mosquito.
Cryo‐EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution
Authors: Golubev Alexander , Fatkhullin Bulat , Khusainov Iskander , Jenner Lasse , Gabdulkhakov Azat , Validov Shamil , Yusupova Gulnara , Yusupov Marat , Usachev Konstantin 
Published: August 2020

Staphylococcus aureus is a bacterial pathogen and one of the leading causes of healthcare‐acquired infections in the world. The growing antibiotic resistance of S. aureus obliges us to search for new drugs and treatments. As the majority of antibiotics target the ribosome, knowledge of its detailed structure is crucial for drug development. Here, we report the cryo‐EM reconstruction at 3.2 Å resolution of the S. aureus ribosome with P‐site tRNA, messenger RNA, and 10 RNA modification sites previously not assigned or visualized. The resulting model is the most precise and complete high‐resolution structure to date of the S. aureus 70S ribosome with functional ligands.
An Advanced Dual‐Function MnO2‐Fabric Air Filter Combining Catalytic Oxidation of Formaldehyde and High‐Efficiency Fine Particulate Matter Removal
Authors: Dai Zijian , Zhu Jie , Yan Jiaqi , Su Jiafei , Gao Yunfei , Zhang Xing , Ke Qinfei , Parsons Gregory N. 
Published: August 2020

AbstractComprehensive treatment of indoor contaminants such as volatile organic compounds (VOCs) and fine particulate matter (PM2.5) using transition metal oxide catalysts or functional fibrous filters has gained substantial attention recently. However, coupling VOC oxidation catalysts into high‐performance filter systems remains a challenge. Herein, an overall solution to strongly bind manganese dioxide (MnO2) nanocrystals onto polypropylene (PP) nonwoven fabrics is provided. For the first time, uniform heterogeneous nucleation and growth of MnO2 onto PP nonwoven fabrics using intermediate inorganic nucleation films, including Al2O3, TiO2, and ZnO, formed conformally on the fabrics via atomic layer deposition (ALD) are demonstrated. How different ALD thin films influence the crystallinity, morphology, surface area, and surface oxygen species of the MnO2 grown ALD‐coated PP fibers is further investigated. In addition to uniformity and integrity, ZnO thin films give rise to MnO2 crystals with the largest fraction of available surface oxygen, enabling 99.5% catalytic oxidation of formaldehyde within 60 min. Moreover, the metal oxide filters provide excellent PM removal efficiencies (ePM), achieving ePM2.5 90% and ePM10 98%, respectively, making the approach an outstanding method to produce fully dual‐functional filtration media.
TiO2 Nanocrystal‐Framed Li2TiSiO5 Platelets for Low‐Voltage Lithium Battery Anode
Authors: He Di , Wang Boya , Wu Tianhao , Su Heng , Zhang Xu , Ren Yang , Xu Gui‐Liang , Liu Zhiwei , Wang Jinshu , Amine Khalil , Yu Haijun 
Published: August 2020

AbstractTitanium‐based anode materials are attracting considerable attention for use in high‐performance lithium‐ion batteries, but the compromised energy density caused by high voltage plateaus and unsatisfactory capacities severely retards their practical applications. Herein, a molten‐salt synthesis of Li2TiSiO5 crystalline platelets and a subsequent selective facet modification by in situ growth of TiO2 nanocrystal frames are facilely achieved. The discharge voltage plateau at around 0.5 V renders the Li2TiSiO5 anode safe compared with graphite and confers a high energy density compared with zero‐strain Li4Ti5O12 anode. With the optimized size, structure, and content of modified TiO2 nanocrystals associated with the exposed (001) plane of Li2TiSiO5, the Li2TiSiO5‐based anodes can deliver a capacity of above 300 mAh g−1, enhanced rate performance, and a capacity retention of 66% after 10 000 cycles. In situ X‐ray diffraction and ex situ transmission electron microscopy have demonstrated the structural stability of the anodes upon charge/discharge. Further theoretical calculation reveals 3D migration paths of Li+ ions in Li2TiSiO5. The selective modification of in situ grown TiO2 nanocrystals on certain facets of crystallites opens a new door for the development of electrode materials possessing superior electrochemical properties.
Enhancing Chemotherapy of p53‐Mutated Cancer through Ubiquitination‐Dependent Proteasomal Degradation of Mutant p53 Proteins by Engineered ZnFe‐4 Nanoparticles
Authors: Qian Jieying , Zhang Wenbin , Wei Pengfei , Yao Guangyu , Yi Tianxiang , Zhang Hao , Ding He , Huang Xiaowan , Wang Meimei , Song Yang , Zhong Suqin , Yang Lijiao , Gao Jinhao , Zhou Zijian , Wen Long‐ping , Zhang Yunjiao 
Published: August 2020

AbstractA significant percentage of human cancers harbor missense mutations in the TP53 gene and express highly stabilized mutant p53 protein (mutp53) with tumor‐promoting gain‐of‐function (GOF) properties. Inducing mutp53 degradation is a viable precision anti‐tumor therapeutic strategy. Based on the previously reported finding that a zinc‐curcumin compound induced mutp53 degradation, a series of ZnFe nanoparticles (ZnFe NPs) are synthesized and it is found that ZnFe‐4, with an Zn:Fe ratio of 1:2, exhibits outstanding mutp53‐degrading capability. ZnFe‐4 induced ubiquitination‐mediated proteasomal degradation of several different mutp53 species, but not the wild‐type p53 protein. Cellular internalization, intracellular Zn++ elevation and increased ROS are all necessary for ZnFe‐4‐induced mutp53 degradation. Degradation of mutp53 by ZnFe‐4, abrogated mutp53‐manifested GOF, leading to increased p21 expression, cell cycle arrest, reduced cell proliferation and cell migration, and cell demise. ZnFe‐4 also sensitized to cisplatin‐elicited killing in p53 S241F ES‐2 ovarian cancer cells, and dramatically improved the therapeutic efficacy of cisplatin in a subcutaneous ES‐2 tumor model. The potential clinical utility of ZnFe‐4 is further demonstrated in an orthotopically‐implanted p53 Y220C patient‐derived xenograft (PDX) breast cancer model. ZnFe‐4 is the first reported mutp53‐degrading nanomaterial, and further materials engineering may lead to the development of zinc‐based nanoparticles with minimal toxicity and maximized mutp53‐degrading capability.
Tailoring Gelation Mechanisms for Advanced Hydrogel Applications
Authors: Nele Valeria , Wojciechowski Jonathan P. , Armstrong James P. K. , Stevens Molly M. 
Published: August 2020

AbstractHydrogels are one of the most commonly explored classes of biomaterials. Their chemical and structural versatility has enabled their use across a wide range of applications, including tissue engineering, drug delivery, and cell culture. Hydrogels form upon a sol–gel transition, which can be elicited by different triggers designed to enable precise control over hydrogelation kinetics and hydrogel structure. The chosen hydrogelation trigger and chemistry can have a profound effect on the success of the targeted application. In this Progress Report, a critical overview of recent advances in hydrogel design is presented, with a focus on the available strategies used to trigger the formation of hydrogel networks (e.g., temperature, light, ultrasound). These triggers are presented within a new classification system, and their suitability for six key hydrogel‐based applications is assessed. This Progress Report is intended to guide trigger selection for new hydrogel applications and inspire the rational design of new hydrogelation trigger mechanisms.
Recent Advances in Semiconducting Monoelemental Selenium Nanostructures for Device Applications
Authors: Huang Weichun , Wang Minmin , Hu Lanping , Wang Cong , Xie Zhongjian , Zhang Han 
Published: August 2020

AbstractInvestigations into semiconductor nanomaterials from both an academic and industrial point of view are of great significance. Selenium (Se) nanostructures, as narrow bandgap semiconductors, have a variety of potential applications in the fabrication of many high‐performance devices. The past decades have witnessed rapid development in new strategies for synthesizing Se nanostructures with controlled sizes, shapes, and structures, whose diverse structure‐dependent nature enables functional Se nanomaterials to have great potentials for modern applications. This review focuses on the synthesis and morphology control of intriguing Se nanostructures, the latest progress in understanding the fundamental properties of Se nanostructures, and the recent advances in high‐performance Se nanomaterial‐based devices for diverse applications. Finally, the challenges and future opportunities for Se nanostructures and Se‐related devices are also discussed.
Living, Self‐Replicating Ferrofluids for Fluidic Transport
Authors: Mirkhani Nima , Christiansen Michael G. , Schuerle Simone 
Published: August 2020

AbstractMagnetic actuation offers a means to wirelessly control flow in ferrofluids for applications including microfluidic pumping and targeted drug delivery. Despite the promise of these concepts, practical use of synthetic ferrofluids as actuators of flow frequently requires high concentrations and is hindered by low ferrohydrodynamic coupling efficiency and inhomogeneous flow fields. Inspired by the magnetic properties and hydrodynamic forms displayed by magnetotactic bacteria (MTB), this work studies the use of these microbes as a living, self‐replicating ferrofluid for improved fluidic transport via magnetically coerced rotation. Using multicore iron oxide nanoparticles as a performance benchmark, MTB under rotating magnetic fields are shown to produce more homogeneous and efficient flow. Coupling is enhanced whether the comparison is made in terms of volume of magnetic material or total volume fraction. To clarify the mechanistic role of interactions with boundaries in transport, a computational model is developed and validated experimentally. Applying this model, two distinct and feasible magnetic control strategies are predicted: a rotating gradient field that generates directional flow despite boundaries that promote flow in opposing directions and a magnetostatic gating field that enables spatially selective actuation. The advantageous properties identified for MTB open a design space for these strategies to be realized.
Design of a Janus‐Faced Electrode for Highly Stretchable Zinc–Silver Rechargeable Batteries
Authors: Song Woo‐Jin , Hwang Chihyun , Lee Sangyeop , Kong Minsik , Kim Jonghak , Park Hyung Keun , Son Hye Bin , Park Gyeongbae , Cho Sunghwan , Song Jun Hyuk , Kim Hyoung Seop , Jeong Unyong , Shin Tae Joo , Song Hyun‐Kon , Park Soojin 
Published: August 2020

AbstractOne of the biggest challenges facing the development of comfortable wearable electronics is the fabrication of stretchable power sources, which are inherently safe and can maintain their electrochemical performance under mechanical elongation. Zinc–silver batteries based on water‐based chemistry have been investigated as viable power supply candidates, owing to their high energy/power density and safety. However, this type of batteries requires a new electrode that can guarantee both high elasticity and stable cycling characteristics of the battery. Here, stretchable zinc–silver rechargeable batteries based on a Janus‐faced electrode, which is a single electrode that comprises a cathode and an anode, are proposed. The Janus‐faced electrode exhibits good mechanical robustness (200 cycles at 200% strain) and retains a high electrical conductivity in the elongated state (2.1 Ω at 100% strain). A proof‐of‐concept stretchable zinc–silver battery based on the Janus‐faced electrode is fabricated to demonstrate the outstanding long‐term cyclability (capacity retentions of ≈90% after 200 cycles), owing to the prevention of short circuit from the zinc dendrite by the unique electrode configuration. Further, the proposed stretchable zinc–silver batteries can deliver a stable electrochemical performance even under a 200% strain while maintaining their functional properties.
Intracellular Fate of Hydrophobic Nanocrystal Self‐Assemblies in Tumor Cells
Authors: Nicolas‐Boluda Alba , Yang Zhijie , Dobryden Illia , Carn Florent , Winckelmans Naomi , Péchoux Christine , Bonville Pierre , Bals Sara , Claesson Per Martin , Gazeau Florence , Pileni Marie Paule 
Published: August 2020

AbstractControl of interactions between nanomaterials and cells remains a biomedical challenge. A strategy is proposed to modulate the intralysosomal distribution of nanoparticles through the design of 3D suprastructures built by hydrophilic nanocrystals (NCs) coated with alkyl chains. The intracellular fate of two water‐dispersible architectures of self‐assembled hydrophobic magnetic NCs: hollow deformable shells (colloidosomes) or solid fcc particles (supraballs) is compared. These two self‐assemblies display increased cellular uptake by tumor cells compared to dispersions of the water‐soluble NC building blocks. Moreover, the self‐assembly structures increase the NCs density in lysosomes and close to the lysosome membrane. Importantly, the structural organization of NCs in colloidosomes and supraballs are maintained in lysosomes up to 8 days after internalization, whereas initially dispersed hydrophilic NCs are randomly aggregated. Supraballs and colloidosomes are differently sensed by cells due to their different architectures and mechanical properties. Flexible and soft colloidosomes deform and spread along the biological membranes. In contrast, the more rigid supraballs remain spherical. By subjecting the internalized suprastructures to a magnetic field, they both align and form long chains. Overall, it is highlighted that the mechanical and topological properties of the self‐assemblies direct their intracellular fate allowing the control intralysosomal density, ordering, and localization of NCs.
Adhesive Hydrogel Patch with Enhanced Strength and Adhesiveness to Skin for Transdermal Drug Delivery
Authors: Jung Hooyeon , Kim Min Kyung , Lee Jun Yup , Choi Seung Woo , Kim Jaeyun 
Published: August 2020

AbstractTransdermal drug delivery patches based on hydrogels are widely used for the transdermal delivery of diverse drugs. However, most hydrogels do not exhibit adequate adhesiveness to skin surface. Herein, tissue adhesive hydrogels consisting of polyacrylamide/polydopamine (PAM/PDA) hydrogels embedded with extra‐large pore mesoporous silica nanoparticles (XL‐MSNs) are proposed based on the synergy of cohesive and adhesive properties. The incorporation of XL‐MSNs leads to enhanced strength and adhesiveness to skin tissue due to an increased cohesive property derived from molecular interactions between XL‐MSNs and polymer chains. The application of XL‐MSNs to the hydrogel–skin tissue interface leads to a further enhanced adhesiveness due to the adhesive gluing role of XL‐MSNs on the interface. The optimized condition enables a 4.9‐fold increase in adhesion energy on the porcine skin tissue, compared to the control PAM/PDA patch. Strong adhesion is achieved immediately after the hydrogel patch is attached onto the skin as well as the surfaces of other organs. Finally, transdermal drug delivery through porcine skin is demonstrated by using the hydrogel patch, with a model drug loaded in the XL‐MSNs embedded in the patch. These observations indicate a simple but highly effective strategy for preparing a highly adhesive hydrogel patch for transdermal drug delivery.
Neuronal Migration on Silicon Microcone Arrays with Different Pitches
Authors: Seo Jeongyeon , Lanara Christina , Choi Ji Yu , Kim Jungnam , Cho Hyeoncheol , Chang Young‐Tae , Kang Kyungtae , Stratakis Emmanuel , Choi Insung S. 
Published: August 2020

AbstractNeuronal migration is a complicated but fundamental process for proper construction and functioning of neural circuits in the brain. Many in vivo studies have suggested the involvement of environmental physical features of a neuron in its migration, but little effort has been made for the in vitro demonstration of topography‐driven neuronal migration. This work investigates migratory behaviors of primary hippocampal neurons on a silicon microcone (SiMC) array that presents 14 different pitch domains (pitch: 2.5–7.3 µm). Neuronal migration becomes the maximum at the pitch of around 3 µm, with an upper migration threshold of about 4 µm. Immunocytochemical studies indicate that the speed and direction of migration, as well as its probability of occurrence, are correlated with the morphology of the neuron, which is dictated by the pitch and shape of underlying SiMC structures. In addition to the effects on neuronal migration, the real‐time imaging of migrating neurons on the topographical substrate reveals new in vitro modes of neuronal migration, which have not been observed on the conventional flat culture plate, but been suggested by in vivo studies.