bluuebunny/crossref_metadata_2025_split huggingface dataset:
The origins of Ethiopia's primary health care expansion: The politics of state building and health system strengthening
Authors: Croke Kevin 
Published: August 2020

AbstractEthiopia’s expansion of primary health care over the past 15 years has been hailed as a model in sub-Saharan Africa. A leader closely associated with the programme, Tedros Adhanom Gebreyesus, is now Director-General of the World Health Organization, and the global movement for expansion of primary health care often cites Ethiopia as a model. Starting in 2004, over 30 000 Health Extension Workers were trained and deployed in Ethiopia and over 2500 health centres and 15 000 village-level health posts were constructed. Ethiopia’s reforms are widely attributed to strong leadership and ‘political will’, but underlying factors that enabled adoption of these policies and implementation at scale are rarely analysed. This article uses a political economy lens to identify factors that enabled Ethiopia to surmount the challenges that have caused the failure of similar primary health programmes in other developing countries. The decision to focus on primary health care was rooted in the ruling party’s political strategy of prioritizing rural interests, which had enabled them to govern territory successfully as an insurgency. This wartime rural governance strategy included a primary healthcare programme, providing a model for the later national programme. After taking power, the ruling party created a centralized coalition of regional parties and prioritized extending state and party structures into rural areas. After a party split in 2001, Prime Minister Meles Zenawi consolidated power and implemented a ‘developmental state’ strategy. In the health sector, this included appointment of a series of dynamic Ministers of Health and the mobilization of significant resources for primary health care from donors. The ruling party’s ideology also emphasized mass participation in development activities, which became a central feature of health programmes. Attempts to translate this model to different circumstances should consider the distinctive features of the Ethiopian case, including both the benefits and costs of these strategies.
Late complications of the Djumbodis system in patients with type A acute aortic dissection
Authors: Vendramin Igor , Piani Daniela , Lechiancole Andrea , Sponga Sandro , Sponza Massimo , Puppato Michela , Bortolotti Uberto , Livi Ugolino 
Published: August 2020

Abstract
The Djumbodis system is a metallic stent designed to prevent false lumen dilatation after repair of acute aortic dissection. Although the exact number of Djumbodis stents inserted worldwide could not be ascertained from a review of the literature, available data indicate 9 specific device-related complications from 4 patient series and 3 case reports: stent deformity or fracture (4), progressive enlargement of the distal false lumen (3) and distal pseudoaneurysm (1); a further patient with pseudoaneurysm of the distal suture line is added from personal observation. The present review confirms the inability of the Djumbodis stent to provide reduction and/or elimination of the false lumen after repair of type A dissection, highlighting peculiar device-related complications. Current survivors with a Djumbodis stent should undergo close follow-up to prevent possible catastrophic events due to device failure.
Surgery out of office hours for type A aortic dissection: does night-time and weekend surgery worsen outcome?
Authors: Gasser Simone , Stastny Lukas , Kofler Markus , Zujs Vitalijs , Krapf Christoph , Semsroth Severin , Ströhle Mathias , Grimm Michael , Dumfarth Julia 
Published: August 2020

Abstract

OBJECTIVES
Immediate surgical repair for type A aortic dissection is gold standard and at most centres is performed by the surgeon on call during night-time and weekends. The objective was to evaluate whether emergency surgery during night-time or weekends has an influence on 30-day mortality.

METHODS
In 319 patients undergoing surgery for type A aortic dissection, skin incision was documented. Patients were divided into 2 groups according to the time point of skin incision (05:00 a.m. to 07:00 p.m. = daytime group; 07:01 p.m. to 04:59 a.m. = night-time group). We also noted whether their surgeries were started on weekdays (Monday 00:00 to Friday 23:59) or weekends (Saturday 00:00 to Sunday 23:59).

RESULTS
The median age was 61 years (interquartile range 49–70) and 69.6% (n = 222) were male. Almost 50% (n = 149) of patients presented in a critical preoperative state. Forty-one percent of patients (n = 131) underwent night-time surgery. There were no differences in baseline data, time from onset of symptoms to surgery or surgical treatment between groups, except from preferred femoral access for arterial cannulation during night-time. Advanced age [odds ratio 1.042, 95% confidence interval (CI) 1.014–1.070], preoperative malperfusion syndrome (odds ratio 2.542, 95% CI 1.279–5.051) and preoperative tamponade (odds ratio 2.562, 95% CI 1.215–5.404) emerged as risk factors for 30-day mortality. Night-time or weekend surgery did not have any impact on 30-day mortality when covariates were considered.

CONCLUSIONS
Based on the natural course of the disease and our results, surgery for type A aortic dissection should be performed as an emergency surgery regardless of time and day.
Comparative investigation of performance of gas dryer and two other types of domestic clothes dryers
Authors: Huang Xiao-Mei , Xiong Lian-Sen , Zheng Yan-Wen , Liu Hui-Qing , Xu Yi-Zhen , Li Yong-Cai 
Published: August 2020

Abstract
The moisture extraction rate (MER) and energy efficiency of domestic gas clothes dryers, heat-pump clothes dryers and electric clothes dryers were assessed. The assessment was performed with regard to five indices: the MER, specific MER, specific thermal energy consumption for dehumidification (mSPC), energy efficiency (ηt) and primary energy efficiency (η1). The effects of the dry mass of clothes (mBD) and the ambient temperature on the performance of the clothes dryers were evaluated. The experiments were divided into two parts. In the first part, the ambient temperature was 20°C, and mBD was set as 1.5, 2.5, 3.5, 4.5 and 6 kg. In the second part, mBD was 3.5 kg, and the performance of the dryers was tested at ambient temperatures of 5, 7.5, 10, 12.5, 15 and 20°C. The experimental results indicated that the gas dryer had the highest MER the heat-pump dryer had the best performance with regard to energy conservation and all three types of dryers had a higher MER and energy efficiency when the ambient temperature increased. The performance of the gas dryer was lower than that of heat-pump dryer when the temperature was 20°C. But when the temperature was &lt; 9.5°C, the primary energy efficiency of the gas dryer was higher than that of the heat-pump dryer.
Marked Reduction of Socioeconomic and Racial Disparities in Invasive Pneumococcal Disease Associated With Conjugate Pneumococcal Vaccines
Authors: Raman Rameela , Brennan Julia , Ndi Danielle , Sloan Chantel , Markus Tiffanie M , Schaffner William , Talbot H Keipp 
Published: August 2020

Abstract

Background
It is not known whether reductions in socioeconomic and racial disparities in incidence of invasive pneumococcal disease (defined as the isolation of Streptococcus pneumoniae from a normally sterile body site) noted after pneumococcal conjugate vaccine (PCV) introduction have been sustained.

Methods
Individual-level data collected from 20 Tennessee counties participating in Active Bacterial Core surveillance over 19 years were linked to neighborhood-level socioeconomic factors. Incidence rates were analyzed across 3 periods—pre–7-valent PCV (pre-PCV7; 1998–1999), pre–13-valent PCV (pre-PCV13; 2001–2009), and post-PCV13 (2011–2016)—by socioeconomic factors.

Results
A total of 8491 cases of invasive pneumococcal disease were identified. Incidence for invasive pneumococcal disease decreased from 22.9 (1998–1999) to 17.9 (2001–2009) to 12.7 (2011–2016) cases per 100 000 person-years. Post-PCV13 incidence (95% confidence interval [CI]) of PCV13-serotype disease in high- and low-poverty neighborhoods was 3.1 (2.7–3.5) and 1.4 (1.0–1.8), respectively, compared with pre-PCV7 incidence of 17.8 (15.7–19.9) and 6.4 (4.9–7.9). Before PCV introduction, incidence (95% CI) of PCV13-serotype disease was higher in blacks than whites (17.3 [15.1–19.5] vs 11.8 [10.6–13.0], respectively); after introduction, PCV13-type disease incidence was greatly reduced in both groups (white: 2.7 [2.4–3.0]; black: 2.2 [1.8–2.6]).

Conclusions
Introduction of PCV13 was associated with substantial reductions in overall incidence and socioeconomic and racial disparities in PCV13-serotype incidence.
Emergence of tigecycline- and eravacycline-resistant Tet(X4)-producing Enterobacteriaceae in the gut microbiota of healthy Singaporeans
Authors: Ding Yichen , Saw Woei-Yuh , Tan Linda Wei Lin , Moong Don Kyin Nwe , Nagarajan Niranjan , Teo Yik Ying , Seedorf Henning 
Published: August 2020

Abstract

Objectives
The recently discovered tigecycline-inactivating enzyme Tet(X4) can confer high-level tigecycline resistance on its hosts, which makes it a public health concern. This study focused on isolation and screening of Tet(X4)-positive Enterobacteriaceae from the gut microbiota of a cohort of healthy individuals in Singapore.

Methods
MinION and Illumina sequencing was performed to obtain the complete genome sequences of Escherichia coli 2EC1-1 and 94EC. Subsequently, 109 human faecal samples were screened retrospectively for eravacycline-resistant Enterobacteriaceae strains, which were further tested for tet(X4) by PCR. The taxonomy of the isolated strains was determined by 16S rRNA gene PCR and Sanger sequencing.

Results
Comparative genomic analysis of E. coli 2EC1-1 and 94EC revealed that both carry tet(X4), which is encoded by IncI1-type plasmids p2EC1-1 and p94EC-2, respectively. Retrospective screening of faecal samples collected from 109 healthy individuals showed that the faecal carriage rate of Tet(X4)-producing Enterobacteriaceae is 10.1% (95% CI = 5.1%–17.3%), suggesting that tet(X4) is widely distributed in the gut microbiota of healthy individuals in Singapore.

Conclusions
To the best of our knowledge, this is the first report on the prevalence of tet(X4) in the gut microbiota of a healthy human cohort, as well as the first description of this resistance mechanism outside of China. Our findings suggest that surveillance of tet(X4) in community settings is vital to monitor the spread of this resistance mechanism.
Technical Note: Assessment of two methods for estimating bone ash in pigs
Authors: Wensley Madie R , Vier Carine M , Gebhardt Jordan T , Tokach Mike D , Woodworth Jason C , Goodband Robert D , DeRouchey Joel M 
Published: August 2020

Abstract
Data from three experiments conducted to evaluate the effects of increasing available P in swine diets were used to compare two different bone processing methods. Our objective was to determine if the procedures influenced treatment differences and the ability to detect changes in the percentage bone ash. In each experiment, pigs (nursery pigs in experiments 1 and 2, and finishing pigs in experiment 3) were fed a wide range of available phosphorus levels provided from either increasing monocalcium P or added phytase. At the completion of each experiment, a subset of pigs was euthanized, and either fibulas (experiments 1 and 2) or metacarpals (experiment 3) were collected to determine the percentage bone ash. Bones were processed by cleaning away all soft tissues followed by ether extraction for 7 d (defatted), or no lipid extraction (non-defatted), and then ashed. In nursery and finishing pigs, defatted bones had increased (P &lt; 0.001) percentage bone ash compared with non-defatted bones. No evidence of a method × treatment interaction or linear and quadratic interactions were observed in bone ash weight and percentage bone ash (P &gt; 0.10) for nursery pigs; however, a linear interaction was detected (P &lt; 0.05) in percentage bone ash for grow-finish pigs. This response was minimal and likely due to increased variation observed in grow-finish pigs when bones were not defatted. The processing method did not affect the ability to detect differences among treatments as a result of changing dietary P concentrations in the nursery or grow-finish pigs. In summary, either non-defatted or defatted bone processing methods can be used to determine bone ash weight and percentage bone ash as a way to assess bone mineralization and dietary treatment differences in nursery pigs; however, the increased variation observed in mature pigs suggests that defatted bone processing is the preferred method for grow-finish pigs.
‘The Indispensable Agent’: Coal and Its Displacements in Victorian Britain
Authors: Fanning Colin 
Published: August 2020

Abstract
Despite the prominent role of fossil fuels in the technological and social shifts of nineteenth-century Britain, coal—as a tangible thing that touched many aspects of Victorian life—has often been left out of histories of design. A topic of keen political and cultural interest in the period, coal was both an object of displacement (extracted, circulated, consumed) and its agent, reworking Britain’s economic and geological landscapes. This article argues that the ‘coal fetishism’ of Victorian Britain was not an inevitable outgrowth of the material’s proliferation, but was produced in part through the activity of designers, civil servants and manufacturers. Examining coal through the paired notions of display and concealment, I first consider how the substance was elevated in cultural terms at spectacles like the Great Exhibition of 1851, where conjoined strategies of pageantry and didacticism reinforced its centrality to national prosperity. I then turn to explore the coal-burning devices shown in these same spectacular events, showing how the fuel forced designers and manufacturers to contain, conceal or otherwise displace its negative effects and by-products. Attempting to re-place the messy materiality of coal into the history of Victorian design, I argue, thus illuminates the larger tensions and ambiguities of industrial modernity.
OLIG2 Immunolabeling of Mesenchymal Chondrosarcoma: Report of 14 Cases
Authors: Yao Kun , Duan Zejun , Yang Shaomin , Du Zunguo , Wang Yin , Qi Xueling 
Published: August 2020

Abstract
Mesenchymal chondrosarcoma (MC) is a rare aggressive mesenchymal sarcoma. Specific markers for the differential diagnosis of MCs remain to be developed. OLIG2 expression has been reported only in neuroepithelial tumors. Recently, OLIG2 expression was found to be involved in the development of NCOA2 fusion-positive alveolar rhabdomyosarcomas. Therefore, we investigated whether OLIG2 expression could be used as a diagnostic marker for MC. We report the clinical pathological and immunohistochemical features of 14 MCs. All tumors showed typical pathological features including biphasic patterns with sheets of primitive round mesenchymal cells and interspersed islands of cartilage. These tumors expressed BCL2, SOX9, and CD99. OLIG2 was robustly expressed in 12/14 of MCs. NCOA2 rearrangement was found in 12 cases. OLIG2 expression was not found in the NCOA2 rearrangement-negative MCs. Notably, OLIG2 expression was not detected in 52 neoplasms (8 Ewing sarcomas, 23 hemangiopericytomas, and 21 chondrosarcomas) that are frequently misdiagnosed as MC. Our findings provide convincing evidence that OLIG2 can serve as a reliable marker in the differential diagnosis of MC and may be a unique neurodevelopmental gene expression signature for the NCOA2 rearranged MCs.
Spectropolarimetric observations of the CIZA J2242.8+5301 northern radio relic: no evidence of high-frequency steepening
Authors: Loi F , Murgia M , Vacca V , Govoni F , Melis A , Wittor D , Beck R , Kierdorf M , Bonafede A , Boschin W , Brienza M , Carretti E , Concu R , Feretti L , Gastaldello F , Paladino R , Rajpurohit K , Serra P , Vazza F 
Published: August 2020

ABSTRACT
Observations of radio relics at very high frequency (&gt;10 GHz) can help to understand how particles age and are (re-)accelerated in galaxy cluster outskirts and how magnetic fields are amplified in these environments. In this work, we present new single-dish 18.6 GHz Sardinia Radio Telescope and 14.25 GHz Effelsberg observations of the well-known northern radio relic of CIZA J2242.8+5301. We detected the relic which shows a length of ∼1.8 Mpc and a flux density equal to $S_{14.25\, \mathrm{ GHz}}=(9.5\pm 3.9)\, \mathrm{ mJy}$ and $S_{18.6\, \mathrm{ GHz}}=(7.67\pm 0.90)\, \mathrm{ mJy}$ at 14.25 and 18.6 GHz, respectively. The resulting best-fitting model of the relic spectrum from 145 MHz to 18.6 GHz is a power-law spectrum with spectral index α = 1.12 ± 0.03: no evidence of steepening has been found in the new data presented in this work. For the first time, polarization properties have been derived at 18.6 GHz, revealing an averaged polarization fraction of $\sim\! 40{{\ \rm per\ cent}}$ and a magnetic field aligned with the ’filaments’ or ’sheets’ of the relic.
Low-redshift tests of Newtonian cosmologies with a time-varying gravitational constant
Authors: Hanımeli Ekim Taylan , Tutusaus Isaac , Lamine Brahim , Blanchard Alain 
Published: August 2020

ABSTRACT
In this work, we investigate Newtonian cosmologies with a time-varying gravitational constant, G(t). We examine whether such models can reproduce the low-redshift cosmological observations without a cosmological constant, or any other sort of explicit dark energy fluid. Starting with a modified Newton’s second law, where G is taken as a function of time, we derive the first Friedmann–Lemaître equation, where a second parameter, G*, appears as the gravitational constant. This parameter is related to the original G from the second law, which remains in the acceleration equation. We use this approach to reproduce various cosmological scenarios that are studied in the literature, and we test these models with low-redshift probes: type-Ia supernovae (SNIa), baryon acoustic oscillations, and cosmic chronometers, taking also into account a possible change in the supernovae intrinsic luminosity with redshift. As a result, we obtain several models with similar χ2 values as the standard ΛCDM cosmology. When we allow for a redshift-dependence of the SNIa intrinsic luminosity, a model with a G exponentially decreasing to zero while remaining positive (model 4) can explain the observations without acceleration. When we assume no redshift-dependence of SNIa, the observations favour a negative G at large scales, while G* remains positive for most of these models. We conclude that these models offer interesting interpretations to the low-redshift cosmological observations, without needing a dark energy term.
Chandra and XMM–Newton observations of A2256: cold fronts, merger shocks, and constraint on the IC emission
Authors: Ge Chong , Liu Ruo-Yu , Sun Ming , Yu Heng , Rudnick Lawrence , Eilek Jean , Owen Frazer , Dasadia Sarthak , Rossetti Mariachiara , Markevitch Maxim , Clarke Tracy E , Jones Thomas W , Ghizzardi Simona , Venturi Tiziana , Finoguenov Alexis , Eckert Dominique 
Published: August 2020

ABSTRACT
We present the results of deep Chandra and XMM–Newton observations of a complex merging galaxy cluster Abell 2256 (A2256) that hosts a spectacular radio relic (RR). The temperature and metallicity maps show clear evidence of a merger between the western subcluster (SC) and the primary cluster (PC). We detect five X-ray surface brightness edges. Three of them near the cluster centre are cold fronts (CFs): CF1 is associated with the infalling SC; CF2 is located in the east of the PC; and CF3 is located to the west of the PC core. The other two edges at cluster outskirts are shock fronts (SFs): SF1 near the RR in the NW has Mach numbers derived from the temperature and the density jumps, respectively, of MT = 1.62 ± 0.12 and Mρ = 1.23 ± 0.06; SF2 in the SE has MT = 1.54 ± 0.05 and Mρ = 1.16 ± 0.13. In the region of the RR, there is no evidence for the correlation between X-ray and radio substructures, from which we estimate an upper limit for the inverse-Compton emission, and therefore set a lower limit on the magnetic field (∼ 450 kpc from PC centre) of B &gt; 1.0 μG for a single power-law electron spectrum or B &gt; 0.4 μG for a broken power-law electron spectrum. We propose a merger scenario including a PC, an SC, and a group. Our merger scenario accounts for the X-ray edges, diffuse radio features, and galaxy kinematics, as well as projection effects.
Detecting the inner regions of discs around sources of microlensing with Roman Space Telescope
Authors: Sajadian Sedighe , Salehi Ali 
Published: August 2020

ABSTRACT
The inner region of circumstellar discs makes an extra near-infrared emission (NIR bump). Detecting and studying these NIR bumps from nearby stars have been done mostly through infrared interferometry. In this work, we study the feasibility of detecting NIR bumps for Galactic bulge stars through microlensing from observations by The Nancy Grace Roman Space Telescope (RST) survey. We first simulate microlensing light curves from source stars with discs in NIR. Four main conclusions can be extracted from the simulations. (i) If the lens is crossing the disc inner radius, two extra and wide peaks appear and the main peak of microlensing light curve is flattened. (ii) In microlensing events with the lens impact parameters larger than the disc inner radius, the disc can break the symmetry of light curves with respect to the time of closest approach. (iii) In caustic-crossing binary microlensing, the discs produce wide peaks right before entering and immediately after exiting from the caustic curves. (iv) The disc-induced perturbations are larger in the W149 filter than in the Z087 filter, unless the lens crosses the disc condensation radius. By performing a Monte Carlo simulation, the probabilities of detecting the disc perturbations by RST are estimated ∼3 and 20 per cent in single and binary microlensing, respectively. We anticipate that RST detects around 109 disc-induced perturbations during its microlensing survey if 5 per cent of its source stars have discs.
First in situ detection of the CN radical in comets and evidence for a distributed source
Authors: Hänni Nora , Altwegg Kathrin , Pestoni Boris , Rubin Martin , Schroeder Isaac , Schuhmann Markus , Wampfler Susanne 
Published: August 2020

ABSTRACT
Although the debate regarding the origin of the cyano (CN) radical in comets has been ongoing for many decades, it has yielded no definitive answer to date. CN could previously only be studied remotely, strongly hampering efforts to constrain its origin because of very limited spatial information. Thanks to the European Space Agency's Rosetta spacecraft, which orbited comet 67P/Churyumov–Gerasimenko for 2 yr, we can investigate, for the first time, CN around a comet at high spatial and temporal resolution. On board Rosetta's orbiter module, the high-resolution double-focusing mass spectrometer DFMS, part of the ROSINA instrument suite, analysed the neutral volatiles (including HCN and the CN radical) in the inner coma of the comet throughout that whole 2-yr phase and at variable cometocentric distances. From a thorough analysis of the full-mission data, the abundance of CN radicals in the cometary coma has been derived. Data from a close flyby event in 2015 February indicate a distributed origin for the CN radical in comet 67P/Churyumov–Gerasimenko.