bluuebunny/crossref_metadata_2025_split huggingface dataset:
“The guild […] manufactures nothing, nor produces any artifact”: Barcelona's Seven Maritime Cargo Handling Guilds, c.1760–1840
Authors: von Briesen Brendan J. 
Published: April 2020

AbstractBy studying the guilds of the seven maritime cargo handling trades of Barcelona, this paper aims to contribute to the relatively limited, but growing scholarship of port labour during the late artisan phase, and of service-sector guilds in general. It examines the relationship between occupational and organizational cultures, the types and means of inculcating human and social capital, and the formal and informal determination of qualification in view of the different guild responses to liberalization and abolition. Unlike guilds in the secondary sector, these corporations were organized horizontally among masters and had neither journeymen, nor apprentices in their respective trades. Some of them provided services individually while others worked collectively. They generally prohibited internal and external employment schemes, and many of them used a turn system or another to level work opportunities. One of these guilds transitioned directly into a trade union; others became owner associations or dissolved into unorganized competitors. The period studied covers the flexibilization of the labour market through progressively advancing liberal reforms of monopolistic guild privileges and the formal abolition of Spanish guilds in 1836. Comparisons with other European ports further highlight the multiplicity of considerations for understanding occupational and organizational cultures and the trajectories of guilds in the service sector.
Management of epistaxis in patients on novel oral anticoagulation therapy
Authors: Ho J P K , Bari N , Riffat F 
Published: April 2020

AbstractBackgroundIndividuals on anticoagulation therapy are at increased risk of bleeding, including epistaxis. There is a lack of available reversal agents for novel oral anticoagulation therapy.ObjectiveThis paper reviews the current literature on epistaxis in the context of novel oral anticoagulation use, in order to recommend guidelines on management.MethodA comprehensive search of published literature was conducted to identify all relevant articles published up to April 2019.ResultsPatients on oral anticoagulation therapy are over-represented in individuals with epistaxis. Those on novel oral anticoagulation therapy were more likely to relapse compared to patients on classic oral anticoagulants or non-anticoagulated patients. Idarucizumab is an effective antidote for bleeding associated with dabigatran use. Recommendations for epistaxis management in patients on novel oral anticoagulation therapy are outlined.ConclusionClinicians need to be aware of the potential severity of epistaxis and the increased likelihood of recurrence. High-quality studies are required to determine the efficacy and safety of andexanet alfa and ciraparantag, as well as non-specific reversal agents.
IgM+ memory B cells induced in response to Plasmodium berghei adopt a germinal centre B cell phenotype during secondary infection
Authors: Pietrzak Halina M. , Ioannidis Lisa J. , Hansen Diana S. 
Published: April 2020

AbstractEmerging evidence started to delineate multiple layers of memory B cells, with distinct effector functions during recall responses. Whereas most studies examining long-lived memory B cell responses have focussed on the IgG+ memory B cell compartment, IgM+ memory B cells have only recently started to receive attention. It has been proposed that unlike IgG+ memory B cells, which differentiate into antibody-secreting plasma cells upon antigen re-encounter, IgM+ memory B cells might have the additional capacity to establish secondary germinal centre (GC) responses. The precise function of IgM+ memory B cells in the humoral immune response to malaria has not been fully defined. Using a murine model of severe malaria infection and adoptive transfer strategies we found that IgM+ memory B cells induced in responses to P. berghei ANKA readily proliferate upon re-infection and adopt a GC B cell-like phenotype. The results suggest that that IgM+ memory B cells might play an important role in populating secondary GCs after re-infection with Plasmodium, thereby initiating the induction of B cell clones with enhanced affinity for antigen, at faster rates than naive B cells.
Motherhood, morality and materiality: how material changes to wartime Cape Town affected discourses around women, racial health and the city, 1914–1919
Authors: Walton Sarah-Jane 
Published: April 2020

AbstractThis article explores ways in which material changes engendered by World War I influenced ideas about Cape Town and its people. For the city's middle classes, these conditions – including a rise in the cost of living, increased urbanization, the growth of factory work for women and the notable presence of soldiers in the city – heightened the sense that Cape Town was a place of increased moral corruption. In particular, females were portrayed as pivotal to the upholding of the moral and racial integrity of the city, nation and empire. Yet the perceived race and class of different Capetonian women influenced the expectations (and accordant condemnations) of their behaviour. This linked to white middle-class anxieties about miscegenation and urban order. As such, discourses around female behaviour during the war represented a nexus between issues of health, race and morality within the South African urban context.
REBT with context of basic psychological needs: RESD-A Scale
Authors: Artiran Murat , Simsek Omer Faruk , Turner Martin 
Published: April 2020

AbstractBackground:Accurate psychometrics benefit from assessing given constructs within specifically defined contexts. The assessment of context-specific irrational beliefs as put forth in rational emotive behaviour therapy (REBT), under the three basic psychological needs described in self-determination theory (SDT), represents a new path for research. Under the umbrella of ‘positive psychology’, a new scale for adolescents combining REBT and SDT is the first step towards conceptualizing irrational beliefs within the three basic psychological needs. The integration of REBT and SDT would provide a more fully integrated view of adolescent mental health, and as such could provide a more cost-effective approach for preventing cognitive, emotive and behavioural disturbances in young people.Aims:The main aim of this paper is to outline the development and validation of the Rational Emotive Self Determination Scale for Adolescents (RESD-A), which measures irrational beliefs about the three basic psychological needs (autonomy, competence and relatedness).Method:To achieve this main study aim, we report the results of four studies that test the factor structure, internal consistency, construct, predictive validity, and test–re-test reliability of the 51-item RESD-A, within samples of Turkish adolescents.Results:Data analyses confirmed the theoretical expectations and yielded promising results for the validity and reliability of the RESD-A.Conclusions:The results suggest that assessment of irrational beliefs in the context of autonomy, competence and relatedness is possible and valuable for the treatment of adolescents.
Where are Solar storm-induced whale strandings more likely to occur?
Authors: Vanselow Klaus Heinrich 
Published: April 2020

AbstractWhale strandings occur in many places worldwide and numerous possible explanations for this phenomenon have been proposed, including the effects of astronomical events such as Solar eruptions on the Earth's magnetic field. Whales use the geomagnetic field for navigation, and its distortion can therefore result in whale strandings in certain regions. However, Solar storms do not have the same impact on the geomagnetic field across the whole of the Earth's surface, and positions nearer to the equator are less exposed to this phenomenon. It is therefore plausible that Solar storms can explain whale strandings at high latitude at least, but not necessarily worldwide. This review considers strandings in relation to the geographical and geomagnetic properties of locations at higher latitudes and to changes in the magnetic field over recent centuries. It also focuses on a Solar storm in December 2015. These considerations suggest that navigation errors due to Solar storms are more likely to occur at higher latitudes, particularly in sea areas where the animals might subsequently swim into a geographic trap and become stranded. For sperm whales (Physeter macrocephalus), the southern Norwegian Sea in conjunction with the shallow North Sea represents such an area.
One pathway to cognitive behaviour therapy integration: introducing assimilative integrative rational emotive behaviour therapy
Authors: Al-Roubaiy Najwan Saaed 
Published: April 2020

AbstractIn this paper, rational emotive behaviour therapy (REBT) is presented as the most comprehensive cognitive behavioural therapy (CBT) to date, with over-arching influence on most of the other therapies that came after it. However, despite REBT’s comprehensiveness and the limitations inherent in other CBT approaches, REBT has its limitations. Limitations in REBT theory are explored and an argument is made in favour of rectifying these limitations by incorporating other approaches into REBT (namely cognitive therapy and compassion-focused therapy) to create a more complete integrative psychotherapy model. It is then argued that psychotherapy integration is the future of CBT mainly due to the fact that it reflects how most therapists practise, and due to its utilization of the common factors theory. Finally, the integrative model – which I callAssimilative Integrative Rational Emotive Behaviour Therapy– is presented and demonstrated using a clinical case example.Key learning aims(1)To understand the limitations of cognitive therapy and third-wave CBT approaches.(2)To appreciate the comprehensiveness and over-arching influence of REBT.(3)To understand the limitations of REBT despite its comprehensiveness.(4)To consider rectifying the limitations in REBT by incorporating other models into it.(5)To appreciate the complementary nature of CFT when integrated into other models.(6)To understand the value and relevance of psychotherapy integration.(7)To consider AI-REBT as one possible pathway to psychotherapy integration in CBT.
Author response: cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: systematic review and meta-analysis
Authors: Pathirana Maleesa M. , Lassi Zohra S. , Roberts Claire T. , Andraweera Prabha H. 
Published: April 2020

AbstractThis commentary is an author response to Lu and Wang, regarding the manuscript entitled ‘Cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: Systematic review and meta-analysis’. We address their concern regarding duplication of studies in the meta-analysis and the quality of included studies.
Infant microbiota in colic: predictive associations with problem crying and subsequent child behavior
Authors: Loughman Amy , Quinn Thomas , Nation Monica L. , Reichelt Amy , Moore Robert J. , Van Thi Thu Hao , Sung Valerie , Tang Mimi L. K. 
Published: April 2020

AbstractInfant colic is a condition of unknown cause which can result in carer distress and attachment difficulties. Recent studies have implicated the gut microbiota in infant colic, and certain probiotics have demonstrated possible efficacy. We aim to investigate whether the intestinal microbiota composition in infants with colic is associated with cry/fuss time at baseline, persistence of cry/fuss at 4-week follow-up, or child behavior at 2 years of age. Fecal samples from infants with colic (n = 118, 53% male) were analyzed using 16S rRNA sequencing. After examining the alpha and beta diversity of the clinical samples, we performed a differential abundance analysis of the 16S data to look for taxa that associate with baseline and future behavior, while adjusting for potential confounding variables. In addition, we used random forest classifiers to evaluate how well baseline gut microbiota can predict future crying time. Alpha diversity of the fecal microbiota was strongly influenced by birth mode, feed type, and child gender, but did not significantly associate with crying or behavioral outcomes. Several taxa within the microbiota (includingBifidobacterium, Clostridium, Lactobacillus, and Klebsiella) associate with colic severity, and the baseline microbiota composition can predict further crying at 4 weeks with up to 65% accuracy. The combination of machine learning findings with associative relationships demonstrates the potential prognostic utility of the infant fecal microbiota in predicting subsequent infant crying problems.
Tolerance of grain sorghum to PRE- and POST-applied photosystem II–inhibiting herbicides
Authors: Norsworthy Jason K. , Richburg Jacob , Barber Tom , Roberts Trenton L. , Gbur Edward 
Published: April 2020

AbstractAtrazine offers growers a reliable option to control a broad spectrum of weeds in grain sorghum production systems when applied PRE or POST. However, because of the extensive use of atrazine in grain sorghum and corn, it has been found in groundwater in the United States. Given this issue, field experiments were conducted in 2017 and 2018 in Fayetteville and Marianna, Arkansas, to explore the tolerance of grain sorghum to applications of assorted photosystem II (PSII)-inhibiting herbicides in combination with S-metolachlor (PRE and POST) or mesotrione (POST only) as atrazine replacements. All experiments were designed as a factorial, randomized complete block; the two factors were (1) PSII herbicide and (2) the herbicide added to create the mixture. The PSII herbicides were prometryn, ametryn, simazine, fluometuron, metribuzin, linuron, diuron, atrazine, and propazine. The second factor consisted of either no additional herbicide, S-metolachlor, or mesotrione; however, mesotrione was excluded in the PRE experiments. Crop injury estimates, height, and yield data were collected or calculated in both studies. In the PRE study, injury was less than 10% for all treatments except those containing simazine, which caused 11% injury 28 d after application (DAA). Averaged over PSII herbicide, S-metolachlor–containing treatments caused 7% injury at 14 and 28 DAA. Grain sorghum in atrazine-containing treatments yielded 97% of the nontreated. Grain sorghum receiving other herbicide treatments had significant yield loss due to crop injury, compared with atrazine-containing treatments. In the POST study, ametryn- and prometryn-containing treatments were more injurious than all other treatments 14 DAA. Grain sorghum yield in all POST treatments was comparable to atrazine, except prometryn plus mesotrione, which was 65% of the nontreated. More herbicides should be evaluated to find a comparable fit to atrazine when applied PRE in grain sorghum. However, when applied POST, diuron, fluometuron, linuron, metribuzin, propazine, and simazine have some potential to replace atrazine in terms of crop tolerance and should be further tested as part of a weed control program across a greater range of environments.
Cross-species transferability of Solanum spp. DNA markers and their application in assessing genetic variation in silverleaf nightshade (Solanum elaeagnifolium) populations from Texas, USA
Authors: Singleton Joshua James , Mangat Puneet Kaur , Shim Junghyun , Vavra Cody , Coldren Cade , Angeles-Shim Rosalyn B. 
Published: April 2020

AbstractSilverleaf nightshade (Solanum elaeagnifolium Cav.) is an invasive species that has successfully spread outside its native range to become a noxious weed in 21 states in the United States and 42 countries worldwide. The successful establishment of S. elaeagnifolium outside its native habitat indicates its innate ability to adapt to a multitude of environments. Phenotypic plasticity and/or genetic adaptation have been identified as key mechanisms underlying the adaptive success of invasive species. Whereas phenotypic plasticity allows a species to buffer changes in the environment by altering its phenotypic attributes within the short term, genetic adaptation is responsible for the longer-term adaptability of plants to heterogeneous environments and is dependent on the amount of genetic variation present in the species. In this study, we screened DNA markers that are specific to tomato (Solanum lycopersicum L.) and Solanum lycopersicoides Dunal for their interspecific transferability to S. elaeagnifolium and determined the applicability of the transferable DNA markers in assessing the extent of genetic variation in populations from Lubbock, Littlefield, and Blackwell, TX. Of the 187 markers screened, 78 successfully amplified targets in S. elaeagnifolium, indicating the evolutionary conservation of marker loci across S. lycopersicum, S. lycopersicoides, and S. elaeagnifolium, despite their genetic divergence millions of years ago. Genotyping of S. elaeagnifolium populations using 50 DNA markers that consistently amplified clear bands in more than 60% of the plants identified nine polymorphic markers with 0.014 to 0.621 polymorphism information content. Genetic diversity analysis by DNA marker profiling established genetic variation among populations and within individuals of different populations. Unweighted paired group method with arithmetic mean analysis grouped the plants into six clusters that are generally defined by selection pressures unique to each collection site. Results of the study indicate the capacity of S. elaeagnifolium for genetic differentiation in response to variable selection pressures within the same geographic region.
Yellow nutsedge (Cyperus esculentus) interference in simulated sweetpotato plant beds
Authors: Meyers Stephen L. , Barickman T. Casey , Main Jeffrey L. , Horgan Thomas 
Published: April 2020

AbstractGreenhouse experiments were conducted in 2016 at Pontotoc and Verona, MS. On March 3 (Pontotoc) and March 7 (Verona), landscape fabric was placed in the bottom of polyethylene lugs, each 0.22 m2, then approximately 5 cm of a 1:1 (v/v) blend of soilless potting media and masonry sand was added. ‘Beauregard’ sweetpotato [Ipomoea batatas(L). Lam.] storage roots weighing between 85 and 227 g, and several with emerging sprouts ≤1 cm, were placed longitudinally in a single layer on the substrate, then covered with an additional 3 cm of the substrate. Sprouted yellow nutsedge (Cyperus esculentusL.) tubers were transplanted equidistantly into sweetpotato-containing lugs at six densities: 0, 18, 36, 73, 109, and 145 m−2. Trials were terminated 55 and 60 d after planting at Pontotoc and Verona, respectively. Predicted total sweetpotato stem cuttings (slips) decreased linearly from 399 to 312 m−2asC. esculentusdensity increased from 0 to 145 m−2. Predicted total slip dry weight at aC. esculentusdensity of 145 m−2was reduced 21% compared with 0 m−2. Predicted rotten sweetpotato storage roots increased from 2.6 to 11.3 m−2asC. esculentusdensity increased from 0 to 145 m−2. In response to increasingC. esculentusdensity, sweetpotato seed roots exhibited increased proximal-end dominance.
Regional Structural Orientation of the Mount Sharp Group Revealed by In Situ Dip Measurements and Stratigraphic Correlations on the Vera Rubin Ridge
Authors: Stein Nathaniel T. , Quinn Daven P. , Grotzinger John P. , Fedo Christopher , Ehlmann Bethany L. , Stack Kathryn M. , Edgar Lauren A. , Fraeman Abigail A. , Deen Robert 
Published: April 2020

AbstractGround‐based bedding orientation measurements are critical to determine the geologic history and processes of sedimentation in Gale crater, Mars. We constrain the dip of lacustrine strata of the Blunts Point, Pettegrove Point, and Jura members of the Murray formation using a combination of regional stratigraphic correlations and bed attitude measurements from stereo Mastcam images taken by the Mars Science Laboratory Curiosity rover. In situ bed attitude measurements using a principal component analysis‐based regression method reveal a wide range of dips and dip azimuths owing to a combination of high stereo errors, postdepositional deformation of strata (e.g., fracturing, rotation, and impact cratering), and different primary depositional dips. These constrain regional dips to be within several degrees of horizontal on average. Stratigraphic correlations between targets observed in the Glen Torridon trough and at the Pettegrove Point‐Jura member contact of Vera Rubin ridge (VRR) constrain dips to be between 3°SE and 2°NW, consistent with nearly flat strata deposited horizontally on an equipotential surface. The Jura member is determined to be stratigraphically equivalent to the northern portion of the Glen Torridon trough. Rover‐based dip magnitudes are generally significantly shallower than the orientation of VRR member contacts measured from High Resolution Imaging Science Experiment‐based traces, suggesting the sedimentary strata and VRR member contacts may be discordant.
The cGAS/STING/TBK1/IRF3 innate immunity pathway maintains chromosomal stability through regulation of p21 levels
Authors: Basit Abdul , Cho Min-Guk , Kim Eui-Yun , Kwon Dohyeong , Kang Suk-Jo , Lee Jae-Ho 
Published: April 2020

AbstractChromosomal instability (CIN) in cancer cells has been reported to activate the cGAS–STING innate immunity pathway via micronuclei formation, thus affecting tumor immunity and tumor progression. However, adverse effects of the cGAS/STING pathway as they relate to CIN have not yet been investigated. We addressed this issue using knockdown and add-back approaches to analyze each component of the cGAS/STING/TBK1/IRF3 pathway, and we monitored the extent of CIN by measuring micronuclei formation after release from nocodazole-induced mitotic arrest. Interestingly, knockdown of cGAS (cyclic GMP-AMP synthase) along with induction of mitotic arrest in HeLa and U2OS cancer cells clearly resulted in increased micronuclei formation and chromosome missegregation. Knockdown of STING (stimulator of interferon genes), TBK1 (TANK-binding kinase-1), or IRF3 (interferon regulatory factor-3) also resulted in increased micronuclei formation. Moreover, transfection with cGAMP, the product of cGAS enzymatic activity, as well as add-back of cGAS WT (but not catalytic-dead mutant cGAS), or WT or constitutively active STING (but not an inactive STING mutant) rescued the micronuclei phenotype, demonstrating that all components of the cGAS/STING/TBK1/IRF3 pathway play a role in preventing CIN. Moreover, p21 levels were decreased in cGAS-, STING-, TBK1-, and IRF3-knockdown cells, which was accompanied by the precocious G2/M transition of cells and the enhanced micronuclei phenotype. Overexpression of p21 or inhibition of CDK1 in cGAS-depleted cells reduced micronuclei formation and abrogated the precocious G2/M transition, indicating that the decrease in p21 and the subsequent precocious G2/M transition is the main mechanism underlying the induction of CIN through disruption of cGAS/STING signaling.