bluuebunny/crossref_metadata_2025_split huggingface dataset:
Personal choice is a nuanced concept – Lessons learned from the gambling field. •
Authors: Hodgins David C. 
Published: November 2020

AbstractThis thoughtful framework to minimize the harm associated with emerging technologies by encouraging collaborations among stakeholders would benefit from adopting the WHO precautionary principle in order to keep public health issues at the core of discussions. It would also be helpful to acknowledge and make transparent the differences in stakeholder priorities, the power differentials among stakeholders, and the importance of institutional duty of care.
UJI HEDONIK: PENGKAYAAN NUTRISI DARI COOKIES COKLAT TEPUNG MANGROVE (Avicennia officinalis) DENGAN PENAMBAHAN TEPUNG KACANG MERAH, TEPUNG WIJEN, DAN TEPUNG HATI AYAM
Authors: Harahap Kurnia Sada , Sumartini Sumartini , Mujiyanti Apri 
Published: November 2020

Cookies adalah makanan ringan yang sering dikonsumsi oleh masyarakat karena rasanya yang manis dan teksturnya yang crunchy. Penambahan variasi tepung kacang merah, tepung wijen, dan tepung hati ayam dapat meningkatkan kandungan zat besi dan kalsium pada Cookies. Selain itu, penambahan tepung buah mangrove api-api dapat dijadikan alternatif pengganti tepung terigu, karena mengandung kadar karbohidrat, vitamin, dan mineral yang cukup tinggi. Walaupun subtitusi berbagai jenis tepung tersebut memiliki manfaat dalam konten zat gizi, namun masih terdapat beberapa kendala seperti karakteristik tepung mangrove yang kasar dan aroma yang kurang disukai dari tepung hati ayam membuat Cookies coklat kurang disukai panelis. Oleh sebab itu, penelitian ini bertujuan mencari komposisi terbaik dari tepung mangrove komposisi dari tepung sub tersebut Tujuan penelitian ini adalah untuk mengetahui tingkat kesukaan panelis dalam pembuatan Cookies coklat tepung buah mangrove api-api dan pengaruhnya terhadap tingkat penerimaan panelis dengan pengujian hedonik. Penelitian ini menggunakan metode Rancangan Acak Lengkap yang terdiri dari 4 formulasi perlakuan yaitu perlakuan A ( 40% Tepung Mangrove, 20% Tepung Mocaf, 20 % Tepung Kacang merah,10%Tepung Hati ayam dan 10% Tepung wijen ) ,B( 50% Tepung Mangrove, 20%Tepung Mocaf, 10 % Tepung Kacang merah, 15% Tepung Hati ayam dan 5 % Tepung wijen ) , C ( 60% Tepung Mangrove, 20% Tepung Mocaf, 5 % Tepung Kacang merah, 10% Tepung Hati ayam dan 5% Tepung wijen ) dan D( 100 % Tepung Terigu) sebagai kontrol. Data yang diperoleh dari hasil penelitian akan diuji dengan uji normalitas, uji homogenitas, dilanjutkan dengan Analysis of Varians (ANOVA) dan uji lanjut Beda Nyata Jujur dan pengujian bersih. Sedangkan perlakuan uji panelis terbaik yaitu formula dilihat dari tekstur , rasa, warna, dan aroma.
Evaluating the qualities of probiotic products by a DGGE-based procedure
Authors: Hanh Tran My , Thi Dung Cao , Thi Thanh Huyen Tran , The Hai Pham 
Published: November 2020

The quality of the probiotics is determined by the microbiological composition and can thus be verified by analyzing this characteristic. The use of the Denaturing Gradient Gel Electrophoresis (DGGE) allows the detection of each microorganism through the corresponding band on the gel, which can be considered as the "bar code" of that microorganism. This "bar code” principle demonstrates the potential for the application of DGGE technology to test microbial probiotics with or without a bacterium as registered to assess whether they are qualified. As such, in this study, we experiment the application of DGGE method to test 10 commercial probiotic products, with a focus on products consisting of only bacteria which dominate the market. First, we performed DNA genome extraction and amplification of 550 bp DNA of the 16S rDNA by PCR. Then, the amplicon was analysed on polyacrylamide gels containing a 30% to 60% linear denaturing gradient of urea and formamide. Microbial composition of 7 of the 10 products showed a strong correlation between DGGE results with product labeling as well as isolation of micoorganism. This study thus demonstrates the potential application of DGGE technology in evaluating the qualities of probiotic products.
Conjugation of nanomaterials containing rare-earth ion Tb3+ with CD133 monoclonal antibody and its potentials for labeling colon cancer cells (HT-29)
Authors: Nhat Minh Le , Trong Nhan Vo , Thi Nga Nguyen , Thu Huong Tran , Thi Kim Hue Phung , Thi Thao Do 
Published: November 2020

Nanotechnology is the key technology that brings many important applications in biomedical research.Nanolantanites present high stability, easy fabrication and functionalization. Tb3+ ion-containing nanomaterial, a specific type of nanolantanites, possess great prospects. In addition, cancer stem cells (CSCs) are directlyrelated to drug resistance, metastasis, recurrent cancer, etc. Therefore, CSCs are considered as the target forcancer researching and for discovery of more effective therapies. CD133, a trans-membrane glycoprotein, isone of the typical markers that are found to appear very commonly on the surface of many types of CSCs. Inthis study, CD133 monoclonal antibody (MAb) was cojugated with nanomaterials containing Tb3+. Thecoupling between fluorescented nanomaterials containing Tb3+ ions and CD133 MAb was then incubated withhuman colon cancer cells (HT-29) to evaluate its ability to label CSCs in vitro. The results showed thatnanorods containing rare-earth based Tb3+ ions which were fabricated by hydrothermal method, present thelength of about 300 - 800 nm and the diameter in range of 40 - 50 nm. The Tb3+ nanoparticals also havehexagonal structure of terbium phosphate monohydrate and green illuminant. Tb3+ nanorods were also furthersurface silica coated and amino-silane functionalized. This nanostructure was successfully combined withmonoclonal antibodies against CD133 which labelled the surface marker of HT-29 human colon cancer cells.As a result, the combination of CD133+TbPO4@Silica-NH2 (functionalized surface) showed strongerluminescence than the CD133+TbPO4 unfunctionalized combination.
Evaluation of the effects of agricultural LED lighting on in vitro propagation of Cordyceps militaris (Link.) Fries
Authors: Hong Gam Do , Huong Huynh Duong , Thi Lan Anh Phan , Hoang Duong Nguyen , Thi Kim Hoa Do 
Published: November 2020

In this study, the effects of various agricultural LED lights (LED NN), including single red LED (R), single blue LED (B), and four combinations of blue, red, and warm white (W) LED (BR, BRW1, BRW2, BRW3) on the growth and development of C. militaris (Link.) Fries were evaluated in vitro. After 7 days, samples subjected to LED NN showed shorter sporocarp sprouting time and higher sprouting ratio than the control, which was subjected to T5 fluorescent light. After 2 months, LED lights with high red ratio, such as single red LED and LED BR, had suppressing effect on the growth and development of C. militaris (Link.) Fries. On the other hand, combinations of red, blue, and warm white such as LED BRW1, LED BRW2, and LED BRW3 had the positive impact on the growth and development of this fungus. Notably, samples subjected to LED BRW2 reached 5.79 cm in height, fresh biomass of 3.67 g/20 samples. Cordycepin and Adenosine levels were 64.2 and 6.37 mg/100 g fresh mass, respectively. All of studied indicators were the higher compared to those of the control and other LED lighting schemes. Therefore, it can be conlcuded that LED lighting combination with BRW2 ratio of 1:5:1 and luminous intensity of 45±2 µmol.m-2.s-1 (511,59 Lux) was suitable for the growth and development of C. militaris (Link.) Friesand a potential replacement of fluorescent light for C. militaris (Link.) Friesin vitro propagation.
Isolation and screening producing growth regulator cyanobacteria strains
Authors: Thi Oanh Doan , Thi Thuy Duong , Thi Thu Lien Nguyen , Thi Mai Anh Dang , Thi Quynh Hoang , Minh Thang Hoang , Thi Nguyet Vu , Phuong Quynh Le Thi 
Published: November 2020

Cyanobacteria are photosynthetic microorganisms that have their biosynthesis capacities for secondary compounds with the high application value. They can produce a variety of bioactive compounds such as lipopeptides, fatty acids, toxins, carotenoids, vitamins and plant growth regulators which could be released into the culture medium. The present study aimed to isolate and screen cyanobacteria strains that could synthesize phytohormone, indole-3-acetic acid (IAA) from paddy soild and fresh water ecosystems (canals, river). Soil and water samples were collected from diferent provinces (Bac Giang, Thanh Hoa and Hue). Indole-3-acetic acid was extracted from the culture of isolated cyanobacteria strains and identified using the Salkowski method. As a result, total 10 strains belonging to 4 genera including Nostoc, Anabena, Geitlerinema and Planktothricoides were susscessful isolated from river, canal and rice field. The morphology of isolated taxa was characterized and monoalgal cultures were grown in BG 11 medium. In L-tryptophan-enriched growth media, all cyanobacteria strains in this research were able to biosynthesize growth regulators with IAA concentrations ranging from 9.1 to 95 µg/mL. Among the isolated cyanobacteria strains, the Planktothricoides raciborskii showed potential for the production of IAA even in the absence of tryptophan in the culture medium. Research results of the L-tryptophan concentration effect on the ability of IAA biosynthesis of this cyanobacteria strain showed that IAA concentration increased gradually and reached the highest value (118,28 ± 2,00 µg/mL) when supplementing L- tryptophan in culture medium at 900 µg/mL. The capacity of producing IAA makes these isolated cyanobacteria an appopriate cadidate for agricultural biotechnology.
Enhanced bioremediation of crude oil polluted water by a hydrocarbon-degrading Bacillus strain immobilized on polyurethane foam
Authors: Thi Quynh Hoa Kieu , Vu Giang Nguyen , Thi Yen Nguyen , Duc Huynh Mai , Huu Dat Nguyen , Thi Nga Vuong , Thi Thu Ha Nguyen , Thi Phuong Pham 
Published: November 2020

During the production and transportation of petroleum hydrocarbons, unsuitable operation and leakage may result in contamination of water and soil with petroleum hydrocarbons. Petroleum contamination causes significant marine environmental impacts and presents substantial hazards to human health. Bioremediation of contaminated water and soil is currently the effective and least harmful method of removing petroleum hydrocarbons from the environment. To improve the survival and retention of the bioremediation agents in the contaminated sites, microbial cells must be immobilized. It was demonstrated that immobilized microbial cells present advantages for degrading petroleum hydrocarbon pollutants compared to free suspended cells. In this study, the ability of a Bacillus strain (designed as Bacillus sp. VTVK15) to immobilize on PUF and to degrade crude oil was investigated. The immobilized Bacilllus strain had the highest number (5.38 ± 0.12 Í 108 CFU/g PUF) and a maximum attachment efficiency of 92% on PUF after 8 days. Analysis by GC-MS revealed that both free and immobilized cells of Bacillus sp. VTVK15 were able to degrade 65 and 90% of the hydrocarbons in 2% (v/v) crude oil tested after 14 days, respectively. The results suggest the potential of using PUF-immobilized Bacillus sp. VTVK15 to bioremediate petroleum hydrocarbons in an open marine environment.
Coronavirosis: signos y síntomas con un enfoque en SARS CoV-2. Una revisión comparativa entre especies.
Authors: Yañez Esparza A. , Ortuño Sahagún D. 
Published: November 2020

La enfermedad de la COVID-19 afecta a humanos y es causada por el coronavirus SARS CoV-2. Es una afección emergente que se caracteriza por causar fiebre, malestar, fatiga, dificultad respiratoria, tos seca, diarrea y dolor de cabeza; en los casos más graves puede ocasionar neumonía severa, ocasionalmente conjuntivitis y erupciones cutáneas. Recientemente se ha demostrado que SARS CoV- 2 es capaz de infectar otras especies y estas pueden presentar signos similares a los de COVID-19. Esta revisión hace una comparación de los signos y síntomas de las coronavirosis que afectan a las principales especies domésticas. Adicionalmente, presenta una recopilación de reportes zoosanitarios y trabajos experimentales de la susceptibilidad de animales ante la infección de SARS CoV-2, ya sea por contacto con personas positivas a SARS CoV-2 o por inoculación experimental. Finalmente, se comparan los signos en animales con los síntomas de la enfermedad de la COVID-19 y se demuestra que los animales filogenéticamente más cercanos al humano fueron también los más susceptibles.La enfermedad de la COVID-19 afecta a humanos y es causada por el coronavirus SARS CoV-2. Es una afección emergente que se caracteriza por causar fiebre, malestar, fatiga, dificultad respiratoria, tos seca, diarrea y dolor de cabeza,; en los casos más graves puede ocasionar neumonía severa, ocasionalmente conjuntivitis y erupciones cutáneas. Recientemente se ha demostrado que SARS CoV- 2 es capaz de infectar otras especies y estas pueden presentar signos similares a los de COVID-19. Esta revisión hace una comparación de los signos y síntomas de las coronavirosis que afectan a las principales especies domésticas. Adicionalmente, presenta una recopilación de reportes zoosanitarios y trabajos experimentales de la susceptibilidad de animales ante la infección de SARS CoV-2, ya sea por contacto con personas positivas a SARS CoV-2 o por inoculación experimental. Finalmente, se comparan los signos en animales con los síntomas de la enfermedad de la COVID-19 y se demostró que los animales filogenéticamente más cercanos al humano fueron también los más susceptibles.
Atividade física, propósito de vida de idosos ativos da comunidade: um estudo transversal
Authors: Ferreira Duarte Tarcia Cristina , Da Silva Lopes Higo , Morais Campos Hércules Lázaro 
Published: November 2020

INTRODUÇÃO: A atividade física feita de maneira regular tem grande eficácia no retardo do declínio fisiológico do processo do envelhecimento, mantém e otimiza a capacidade física, melhora a funcionalidade e tem expressão no propósito de vida na velhice. OBJETIVO: caracterizar e descrever as condições sociodemográficas, físicas e de propósito de vida em um grupo de idosos praticantes de atividade física regular no interior do Amazonas. MÉTODOS: Estudo transversal com idosos ativos da comunidade que realizam atividade física em suas comunidades por pelo menos 3 vezes na semana em torno de 50 minutos. Estes foram avaliados através de questionários e escalas validadas: Mini Exame Exame Estado Mental (MEEM), Teste de Trilha, Propósito de Vida, Teste Short PhysicalPerformanc e Battery (SPPB), Índice de Comorbidades Funcional, Escala numérica de dor e foram coletados dados referentes às características sociodemográficas. RESULTADOS: Dos 36participantes,100% são naturais do interior do Amazonas; 28 (77%) sobrevivem com renda mensal de salário mínimo; 27(75%) relatam sentir dor em alguma parte do corpo e 21(58,3%) apresentaram sobrepeso ou obesidade grau 1,33(91,6%) diz se sentir bem quando pensam no passado e no futuro. CONCLUSÃO: apesar de sentir dor, de baixa renda e baixa escolaridade,os idosos praticam atividade física que traz benefícios como manutenção da saúde física, diminuição dos sintomas depressivos, percepção de realização, motivação, satisfação e felicidade em viver.
Cross-cultural adaptation, reliability, and validity of Kannada version of Fear Avoidance Belief Questionnaire in chronic low back pain
Authors: Kumar Ajay , Pithadia Kinari , Kumar Deepak , Sannasi Rajasekher 
Published: November 2020

INTRODUCTION: Activity of daily living (ADL) among the people with Chronic low back pain (CLBP) can be determined by Fear Avoidance Beliefs Questionnaire (FABQ). The Fear Avoidance Beliefs Questionnaire (FABQ) is a valid and reliable self-reporting questionnaire evaluating the patient’s attitude and beliefs toward the effect of physical activity and works on their LBP. Till the date it was translated into various languages but is not available in Kannada language.Hence, we aimed to translate FABQ questionnaire into Kannada (FABQ-KA) and to study reliability and validity of Kannada version, FABQ-KA. METHODS: Translation and cross-culture adaptation were performed according to the guidelines followed internationally. Those are: translation, synthesis, back-translation, revision by expert committee, pretesting and appraisal by advisory committee. Content validation was excuted by the panel of 10 pre-identified members who were experts in using Kannada and English. They were provided with five options, “agree”, “strongly agree”, “neutral”, “disagree” and “strongly disagree”. for providing their valuable opinion regarding kannada translated content of FABQ-KA. The psychometric properties were tested by administering the questionnaire to 60 samples (18 to 75 years) was recruited by Purposive sampling. For test-retest reliability, people with CLBP were tested after a week by Intra-class correlation coefficient (ICC) and internal consistency was assessed by Cronbach's alpha (?). RESULTS: The demographic dimensions, age, height, weight and BMI for patients with CLBP recruited, n=60 were 41.50±10.59 (Years), 154.37±10.74 (cm), 62±11.04 (kg) and 25.99±4.47 (kg/m2) respectively with duration of LBP of 20.35±13.62 weeks. The content validity of kannada translated FABQ-KA by a panel of 10 experts were found to be, I-CVI of individual items of FABQ-KA ? 0.80 and the overall S-CVI for idiomatic equivalence (S-CVI =89.9±6.33)%,, semantic equivalence (S-CVI =93±5.16)% and content relevance(S-CVI=90.7±6.61)%.were ? 0.90 or (? 90%). The test-retest reliability of FABQ-KA was good (ICC (2,1) = 0.83). Internal consistency was found to be good (Cronbach’s alpha = 0.91). CONCLUSIONS: The FABQ-KA translation and adaptation processes were successful; the adapted instrument demonstrated good psychometric properties. The FABQ-KA has proven to be reliable and valid tool and can be used in the Kannada speaking patients with CLBP.
Nível do índice de sucesso de extubação de uma unidade de terapia intensiva pediátrica
Authors: Viana Helly Paula Santos , Rodrigues Roquenei da Purificação , Da Silva Talita Bezerra 
Published: November 2020

INTRODUÇÃO: O sucesso do desmame da ventilação mecânica invasiva (VMI) é definido pela manutenção da ventilação espontânea durante um período de pelo menos 48h após a interrupção da ventilação artificial. Considera-se insucesso ou falência do desmame, se o retorno à ventilação artificial for necessário neste período. OBJETIVO: descrever o índice de sucesso de extubação de uma Unidade de Terapia Intensiva Pediátrica (UTIP). MÉTODOS: Estudo descritivo, transversal e retrospectivo. A população do estudo foi composta por pacientes com idade superior à 28 dias de vida e inferior à 14 anos de idade de ambos os sexos, no Hospital Estadual da Criança (HEC), submetidos à VMI através do tubo orotraqueal (TOT) por mais de 24h e que passaram pelo processo de desmame, tendo como base, o protocolo de extubação, da unidade hospitalar, realizado no período de janeiro à agosto de 2017 e abril à julho de 2018. A análise de dados se deu por meio da estatística descritiva, calculando a média e os valores relativos. RESULTADOS: A amostra foi composta por 74 registros, o tempo médio do uso da VMI foi de 8,67 dias. Ao ser aplicado o teste de respiração espontânea para a realização da extubação, 82,3% crianças apresentaram alto índice de sucesso e 17,56% médio índice. Destas, 72,97%tiveram sucesso na extubação. CONCLUSÃO: Os registros que compuseram esta amostra demonstraram uma menor taxa de falha de extubação, correspondendo ao observado em outros serviços de referência.
Relação entre a posição Canguru e a estabilidade fisiológica e equilíbrio sono-vigília de recém-nascidos prematuros na UTIN e percepção materna
Authors: Nisi Karine Souza Andrade , Andreazza Marimar Goretti , Gomes Evellin de Oliveira , Soares Palmira Donda , Motter Arlete Ana 
Published: November 2020

INTRODUÇÃO: A posição canguru é uma estratégia do Método Canguru que aproxima as mães de seus filhos, promovendo estabilidade fisiológica. OBJETIVO: Analisar a estabilidade fisiológica e equilíbrio sono-vigília dos RNPTs de uma Unidade de Terapia Intensiva Neonatal (UTIN) em um hospital público universitário, bem como a percepção materna quanto a posição canguru. MÉTODO: Estudo observacional com análise de resultados qualitativos e quantitativos. Desenvolveu-se entre julho a dezembro de 2017 na UTIN. Os dados foram coletados dos prontuários dos RNs. Os parâmetros fisiológicos e estado comportamental de escala sono vigília, antes e após 50 minutos na posição canguru. E as mães responderam à 10 perguntas abertas quanto a seus sentimentos no contato pele a pele. RESULTADOS: Foram incluídos 18 recém-nascidos e 10 mães responderam a entrevista. Os RNs mantiveram a frequência cardíaca (p=0,28) e saturação periférica de oxigênio (p=0,77) nos limites da normalidade, a temperatura corporal apresentou diferença estatisticamente significante (p=0,01) variando entre 36,5 e 36,7o. Os RNs mudaram o estado comportamental e as mães perceberam estas mudanças durante a realização da posição canguru e se sentiram mais próximas dele por meio do contato pele a pele. CONCLUSÃO: Os recém-nascidos posicionados em canguru no tórax de suas mães mantiveram seus dados fisiológicos estáveis e a temperatura corporal dos mesmos apresentou pequeno acréscimo dentro da normalidade, mostrando ser seguro estar na posição canguru. As mães perceberam que tal ato as aproximou de seus filhos despertando sentimentos positivos de alegria, emoção e amor, indo ao encontro do que é preconizado pelo Método Canguru.
Perfil clínico, sociodemográfico e funcional de indivíduos com aneurisma cerebral internados em um hospital de referência em Salvador/BA
Authors: De Oliveira Vanessa Cristina Santos , Dos Santos Ariana Prazeres , Dos Anjos Jorge Luis Motta , Rosa de Castro Isabella Pereira 
Published: November 2020

INTRODUÇÃO: Aneurisma cerebral (AC) é a dilatação anormal de uma artéria que irriga o cérebro. Cerca de 3,2% da população mundial apresenta algum AC com potencial risco de evoluir para hemorragia subaracnóidea (HSA). OBJETIVO: Descrever o perfil clínico, sociodemográfico e funcional de indivíduos com diagnóstico clínico de AC atendidos em Salvador/BA. MÉTODO: Estudo observacional e transversal, realizado em um hospital de referência em Salvador/BA. Indivíduos maiores de 18 anos com diagnóstico de AC (N=25) roto ou não roto, foram avaliados o perfil sociodemográfico (idade, sexo, escolaridade e ocupação), clinico (comorbidades, hábitos de vida e nível de consciência através da ECG, Escala de Coma de Glasgow) e funcional (MRC, Medical Research Council; ECT, Escala de Comprometimento de Tronco e Rankin Modificada). Variáveis qualitativas foram apresentadas por frequências relativas e as variáveis quantitativas por meio de médias, desvio-padrão ou medianas e intervalo mínimo e máximo. RESULTADOS: Foram incluídos 13 indivíduos diagnosticados com AC, idade mediana de 51, sendo 84,6% do sexo feminino, 30,8% ativos no mercado de trabalho. 61,5% da população apresentou AC não roto e ECG 15. Observamos HAS em 53,8% e obesidade em 7,7%. Cerca de 61,5% eram sedentários, 15,4% etilistas e 30,8% tabagistas. Na avaliação da funcionalidade, o escore MRC mediano foi de 54, Rankin a mediana foi 4 e na ECT de 19,5. CONCLUSÃO: Os achados demonstram uma predominância dos AC em mulheres e declínio funcional dos indivíduos durante o internamento, tornando-se necessário intervenções que visem minimizar possíveis perdas funcionais nesta população.