bluuebunny/crossref_metadata_2025_split huggingface dataset:
Online Marketing Impact on Micro-Enterprises: An Insight through Visibility in Search Engines
Authors: Kovalenko Artoym , Kuzmenko Yuliya 
Published: April 2020

Abstract
Transforming marketing into an online format is an inevitable process of developing an information economy. The study of information flows allows using a comprehensive approach to the problems of online marketing. The activities of small businesses are characterized by various limitations, but it is an important factor in increasing the flexibility of the economy and the ability to adapt to changes. The gap in the theory and practice of conducting Internet marketing activity in micro enterprises has helped to shape the relevance of this work. The aim of the study is to research the phenomenon of visibility of Internet websites from the perspective of marketing information flows in the activities of small businesses. The article discusses the theoretical foundations of marketing information flows, Internet marketing, inbound marketing and visibility of Internet websites. The research methodology is based on the methods of marketing analysis and sociological surveys. The study was conducted on the basis of the sampling of 306 websites of small enterprises. The study examined the characteristics of the websites of small enterprises, reflecting the effectiveness of Internet marketing activities. The results show that there is a correlation between the number of applied methods of Internet marketing and the visibility of the websites of small organizations in the search engine. The existence of particular cases of the use of single methods of Internet marketing has been revealed, providing high visibility and effectiveness of Internet marketing activities of small organizations.
Motivators and its impacts on job satisfaction in FDI companies - A case study of Eurowindow Vietnam
Authors: Tri Ho Thanh , Ngoc-Tan Nguyen , Gregar Aleš , Pavelkova Drahomira 
Published: April 2020

Abstract
This study investigates the factors motivating workers and their levels of job satisfaction at Eurowindow Vietnam – an FDI company in the furniture industry based in Hochiminh City, Vietnam. Data for this study were collected by a surveying 202 office workers of the company. A Likert-scale response format questionnaire was used to identify employment attitudes and job satisfaction. The research was carried out based on the theoretical aspects of job satisfaction. Cronbach’s alpha and exploratory factor analysis (EFA) were deployed to test the unidimensionality, reliability, and validity of measurement scales. Correlation analysis was carried out to estimate the relation between dependent and independent variables, and within the independent ones. Moreover, multiple regression analysis was adopted to test the hypotheses of the study. The level of job satisfaction was measured by seven dimensions, namely payment, promotion, supervisor, co-workers, work itself, benefits and work environment. The research results showed that work itself, promotion, payment, and supervisor have significant influences on job satisfaction. Findings of this study provide necessary knowledge for the leadership of Eurowindow Vietnam in boosting job satisfaction of their staff. Other FDI enterprises with the same development level may find these results applicable for their organizations. Recommendations for future research are also presented at the end of the study.
Clinical, immunological and genetic characteristic of patients with clinical phenotype associated to LRBA-deficiency in Colombia.
Authors: Martínez-Jaramillo Catalina , Gutierrez-Hincapie Sebastian , Orrego Arango Julio César , Vazuez-Duque Gloria María , Erazo-Garnica Ruth María , Franco Jose Luis , Trujillo-Vargas Claudia Milena 
Published: April 2020

Background: LPS-responsive beige -like anchor protein (LRBA) deficiency is a primary immunodeficiency disease caused by loss of LRBA protein expression, due to biallelic mutations in LRBA gene. LRBA deficiency patients exhibit a clinically heterogeneous syndrome. The main clinical complication of LRBA deficiency is immune dysregulation. Furthermore, hypogammaglobulinemia is found in more than half of patients with LRBA-deficiency. To date, no patients with this condition have been reported in Colombia

Objective: To evaluate the expression of the LRBA protein in patients from Colombia with clinical phenotype associated to LRBA-deficiency.

Methods: In the present study the LRBA-expression in patients from Colombia with clinical phenotype associated to LRBA-deficiency was evaluated. After then, the clinical, the immunological characteristics and the possible genetic variants in LRBA or other genes associated with the immune system in patients that exhibit decrease protein expression was evaluated.

Results: In total, 112 patients with different clinical manifestations associated to the clinical LRBA phenotype were evaluated. The LRBA expression varies greatly between different healthy donors and patients. Despite the great variability in the LRBA expression, six patients with a decrease in LRBA protein expression were observed. However, no pathogenic or possible pathogenic biallelic variants in LRBA, or in genes related with the immune system were found.

Conclusion: LRBA expression varies greatly between different healthy donors and patients. Reduction LRBA-expression in 6 patients without homozygous mutations in LRBA or in associated genes with the immune system was observed. These results suggest the other genetic, epigenetic or environmental mechanisms, that might be regulated the LRBA-expression.
Thematic synthesis HIV prevention qualitative studies in men who have sex with men (MSM)
Authors: Mathias Augusto , Dos Santos Lorruan Alves , Grangeiro Alexandre , Couto Marcia Thereza 
Published: April 2020

Background:Qualitative studies on HIV prevention strategies and methods among men who have sex with men (MSM) allow identify knowledge gaps and improve preventive actions.

Objective:To make a thematic synthesis of the scientific productions that use the qualitative methodology in the strategies and methods of HIV prevention area among MSM.

Methods:We conducted a literature review following the guidelines of the ENTREQ protocol. The analysis included 48 empirical studies published in Portuguese, English and Spanish between 2001 and 2018 available in the Medline, Embase, Scielo, Scopus, Bireme and Web of Science databases.

Results:Where an increased production in the last six years and concentration in northern countries. Seven prevention methods were part of the study, with emphasis on pre-exposure prophylaxis, testing, condoms and behavioral strategies. The main topics discussed were stigma and support and care networks.

Conclusion:we notice that an increasing production on prevention in the men who have sex with men segment results from the emergence of multiple preventive methods and strategies and their combined actions beyond the star role of condoms.
The quality of research with real-world evidence
Authors: Palacios Gómez Mauricio 
Published: April 2020

Most of the medical practice has not been proven by controlled clinical trials, and there are no plans to conduct such trials in order to decrease clinician uncertainty. This happens partly due to the difficulty of making designs with scientific and ethical validity, the costs of this type of research and the time required to generate results, which can be several years. Clinical trials do not have the capability to generate information that allows to make decisions in some sectors of clinical care and public health, such as when an epidemic occurs. Therefore, medical science is based on observational studies, past practices and therapeutic tradition (1).
Observation of clinical data that have defined a clinical behavior precedes the clinical trial. The knowledge about scurvy, the fact that this pathology is considered a nutritional deficiency and its treatment with citrus fruits, originated thanks to the collection of clinical data on sailors, soldiers and prisoners of the British Crown in the 18th and 19th centuries (2). This clinical information, which was collected uniformly and served to produce new knowledge, is what is now known as Real World Data (RWD). A modern definition of RWD would be one that talks about data obtained by any non-interventionist methodology that is collected prospectively and retrospectively from observations of routine clinical practice, and which comes from various sources including data from patients, doctors, hospitals, payers, social data, etc (3).
Implementasi Taâ€™zir Dalam Meningkatkan Kedisiplinan Santri di Pondok Pesantren Al Masruriyyah
Authors: Tasih Amin , Said Ali 
Published: April 2020

Al Masruriyyah Islamic Boarding School is one of the huts of the Tebuireng foundation that is still hungry for discipline in obeying the rules of the cottage. Al Masruriyyah Islamic boarding schools apply taâ€™zir as a form of consequence for santri who violate the rules of the cottage. This study aims to describe and analyze the implementation of taâ€™zir in increasing the discipline of santri in Al Masruriyyah Islamic boarding schools. This study uses a qualitative research approach. Data collection techniques using the method of observation, interviews and documentation. The data obtained will be compiled by reducing/summarizing the data, then presenting the data and drawing conclusions.Â Based on the research shows that: the implementationÂ of taâ€™zir carried out by the management and has been approved by the supervisor and caregivers for giving taâ€™zir every 2 weeks. The criteria for the distribution of taâ€™zir are 3 from the low, medium and heavy according to the mistakes that have been made. The procedure for giving taâ€™zir (1) is advised, (2) in taâ€™zir (3) to be called to Ndalem. The impact of the implementation of taâ€™zir is that there is a better change in the implementation of teaching and learning activities, obeying the rules, and discipline in worship activities to Allah SWT.
Pedagogia Histórico-Crítica: princípios para a formação de professores de Ciências e Biologia
Authors: Diniz Renato Eugênio da Silva , Campos Luciana Maria Lunardi 
Published: April 2020

Neste artigo assume-se a pedagogia histórico- crítica como referencial teórico necessário à formação de professores comprometidos com a educação escolar humanizadora e com a transformação social. São apresentados e analisados quatro princípios, identificados como centrais à formação de professores de Ciências e Biologia: crítica e transformação da sociedade de capitalista e articulação dialética entre educação escolar e sociedade; visão histórica de ser humano; papel transformador do conhecimento sistematizado e a escola e metodologia dialética de ensino. Esses princípios estão articulados e levam a defesa por uma formação sólida teoricamente, pautada na reflexão filosófica.
Introduction
Authors: Stewart David , Lacey Bryant Sue , Edwards Clare , Gilroy Dominic 
Published: April 2020

Every CILIP President has a theme. In David Stewart’s Presidential year in 2019, one of his themes was the need to focus on our own evidence base in libraries and therefore research.
In the NHS “evidence-based healthcare” has been an important driver for change since the 1990s. Evidence based healthcare led directly to evidence based librarianship and that too has been a powerful agent for change in NHS library and knowledge services. Nevertheless, there is much more to do – the power of evidence needs to be recognised across all our professional groups and we need a much more coordinated approach to its funding, development and dissemination.
Аналіз методів прогнозування змін маршрутів передачі даних в бездротових самоорганізованих мережах
Authors: Дівіцький А.С. , Боровик Л.В. , Сальник С.В. , Голь В.Д. 
Published: April 2020

В статті було проаналізовано сучасні дослідження в галузі прогнозування, які розглядають методи підтримання якості функціонування мобільних радіомереж та прогнозування часу перевантаження маршрутів передачі даних. Вказано основні фактори, які впливають на якість функціонування мобільних радіомереж такі як пульсація вхідного трафіка, рівень використання пропускної здатності ліній зв’язку, чутливість до затримок або втрат пакетів. Розглянуто методи прогнозування змін маршрутів передачі даних. Показано реалізацію класичних методів. Вказані переваги і недоліків, які визначають їх ефективність за різних умов застосування. На основі аналізу визначено доцільність проведення комбінування інтелектуальних, причинно-наслідкових, формалізованих та інтуїтивних методів, а саме штучного інтелекту, еволюційних обчислень та управління параметрів. Враховуючи функціональні особливості побудови мобільних радіомереж та вимоги, що висуваються до методів які розглянуті, можливим варіантом рішення є побудова методів заснованих на комбінуванні штучного інтелекту, еволюційних обчислень та управлінням параметрами, що в свою чергу надає можливість розробити нові методи з прогнозування змін маршрутів передачі даних в бездротових самоорганізованих мережах.
Games, experiência lúdica e cognição inventiva
Authors: Oliveira Fátima Cristina Regis Martins de , Perani Leticia , Maia Alessandra 
Published: April 2020

Este estudo argumenta que a experiência lúdica dos games tem o potencial de operar como chave de compreensão da cultura. A discussão teórica está organizada em duas seções. A primeira mostra como a interface gráfica do usuário inspirou-se nos games para tornar-se mais interativa e lúdica. A segunda ressalta que as práticas lúdicas se baseiam em teorias que descentram o humano. Trata-se de uma revisão de literatura, e, como resultado, evidencia-se a necessidade de uma abordagem teórica complexa e transdisciplinar para dialogar com a subjetividade e a cultura hoje.
The works of Shihab ad-din al-Marjani on Islamic scholastic theology
Authors: Shagaviev D. A. 
Published: April 2020

The well-known Tatar historian and theologian Shihab al-Din al-Marjani (18181889), who worked as an imam and teacher of religious disciplines in Kazan, left behind more than 30 scientific and didactic written works. Some of his works were published in Kazan, Istanbul and Cairo. The subjects of the treatises of Marjani touch upon the Islamic faith, law, ethics, Quranic sciences and the history of Islam and Muslim peoples.The most important contribution to Islamic science is his books on Islamic scholastic theology and Sunni dogma. There are seven works on the abovementioned topics from Shihabuddin Marjani’s heritage on Islamic sciences: “al-Hikma al-baligha”, “al-‘Adhb al-furat”, “al-Mathal al-a‘la”, “Haqq al-bayan”, “at-Tariqa al-muthla”, “Haqq al-‘aqida” and “Sharh mukaddimat ar-risalya al-shamsiyya”.This article provides an overview of these works, gives a brief description of them, discusses the prints. It also sheds the light on their issues and points out the inaccessibility of some of them to researchers. Particular attention is paid to the work “al-Hikma al-baligha” (“Mature Wisdom”), which is a commentary on the well-known text in Sunni world, al-‘Aqida al-nasafiyya.The study uses descriptive and historical scientific methods with elements of theological analysis. Accessible sources in Arabic were directly investigated, and the works of contemporaries of the Tatar scholar were also used.
Cyber-Physische Zwillinge
Authors: Czwick Cordula , Martin Georg , Anderl Reiner , Kirchner Eckhard 
Published: April 2020

Kurzfassung
Der neue Begriff „Cyber-Physische Zwillinge“ beschreibt die gleichzeitige Entwicklung der Komponenten, Cyber Zwilling (virtuell) und Physischer Zwilling (real), sowie ihrer bi-direktionalen Wechselwirkung. Cyber-Physische Zwillinge unterscheiden sich vom Digitalen Zwilling durch das Angebot von Services zum Beispiel Handlungsempfehlungen im Cyber Zwilling zum Verhalten des Physischen Zwillings. Diese neue Konzeption wird insbesondere mit der Entwicklung und Anwendung sensorintegrierender Maschinenelemente vorgestellt.
Simulationsplattform für Automatisierungslösungen
Authors: Daniel Christian 
Published: April 2020

Kurzfassung
In den letzten Jahren steigt der Bedarf an die Digitalisierung und den Einsatz von Simulationssystemen im Maschinen- und Anlagenbau rasant. Insbesondere die virtuelle Inbetriebnahme (VIBN) wird verstärkt in Unternehmen etabliert, um die Realisierung von komplexen und flexiblen Produktionseinrichtungen abzusichern. Durch vorgezogene Tests an digitalen Modellen wird die Qualität der Steuerungssoftware verbessert sowie der Start der Produktion und der 100 % Produktionsausstoß beschleunigt. Bei führenden Automatisierungsherstellern und Betreibern gehört inzwischen nicht nur die VIBN zum festen Bestandteil des Engineering-Prozesses. Zunehmend werden Digitale Zwillinge eingesetzt, die neben der VIBN alle Phasen der Automatisierungslösung begleiten. Dieses bildet auch die Basis für neue Geschäftsprozesse und -modelle, die im Sinne der Initiative Industrie 4.0 die Innovationskraft Deutscher Unternehmen beschleunigen soll.
Der Digitale Zwilling über den Produktlebenszyklus
Authors: Massonet Angela , Kiesel Raphael , Schmitt Robert H. 
Published: April 2020

Kurzfassung
Obwohl der Digitale Zwilling ein Schlüsselkonzept des Industrial Internet of Things ist, haben viele Unternehmen davon noch keinen Gebrauch gemacht. Gründe hierfür sind das mangelnde Bewusstsein für Einsatzmöglichkeiten sowie Unklarheit über die Umsetzung. Um eine notwendige Basis für die Umsetzung zu schaffen, wurden am Fraunhofer IPT im Rahmen des International Center for Networked and Adaptive Production ein Konzeptbild und eine Struktur entwickelt, welche das Verständnis fördern sowie die wichtigsten Komponenten und Schritte, die zur Schaffung eines Digitalen Zwillings erforderlich sind, skizzieren
Clinical and computed tomographic (CT) images characteristics in the patients with COVID-19 infection: What should radiologists need to know?
Authors: Lei Pinggui , Huang Zhaoshu , Liu Guoli , Wang Pingxian , Song Wen , Mao Jujiang , Shen Guiquan , Zhou Shi , Qian Wei , Jiao Jun 
Published: April 2020

OBJECTIVE: To evaluate the clinical and computed tomographic (CT) features in the patients with COVID-19 pneumonia confirmed by the real-time reverse transcriptase polymerase chain reaction (rRT-PCR) amplification of the viral DNA from a sputum sample. MATERIAL AND METHODS: Clinical information and CT findings of a total of 14 patients with COVID-19 infection (age range, 12–83 years; females 6) were analyzed retrospectively. The clinical information includes the history of exposure, laboratory results, and the symptoms (such as fever, cough, headache, etc.); CT findings of chest include the extension and distribution of lesion, the ground-glass opacity (GGO), consolidation, bronchovascular enlarged, irregular linear appearances, pleural effusion, and lymphadenopathy. RESULTS: Eight patients had the exposure history for recent travel to Wuhan of Hubei province (8/14, 57%), 6 had the exposure to patients with COVID-19 infection. Significant statistical differences were observed in lymphocyte percentage decreased and C-reactive protein elevated ( p = 0.015). Seven patients had fever, 7 had cough, 2 had headache, 3 had fatigue, 1 had body soreness, 3 had diarrhea, and 2 had no obvious symptoms. In chest CT examination, 10 patients were positive (10/14, 71.43%). Among these patients, 9 had lesions involving both lungs (9/10, 90%), 8 had lesions involving 4 to 5 lobes (8/10, 80%). Most of lesions were distributed peripherally and the most significant lesions were observed in the right lower lobe in 9 patients (9/10, 90%). Nodules were observed in 5 patients (5/10, 50%); GGO, consolidation, and bronchovascular enlarged were shown in 9 patients (9/10, 90%); irregular linear appearances were revealed in 7 patients (7/10, 70%); and pleural effusions were exhibited in 2 patients (2/10, 20%). Last, no patients showed lymphadenopathy. CONCLUSION: There were some typical CT features for diagnosis of COVID-19 pneumonia. The radiologists should know these CT findings and clinical information, which could help for accurate analysis in the patients with 2019 novel coronavirus infection.
A Galicia de Fraguas
Authors: Mandianes Castro Manuel 
Published: April 2020

Este traballo desenvólvese en tres apartados: en primeiro lugar percórrense os movementos intelectuais en voga na época de Fraguas: funcionalismo, estruturalismo, simbolismo, deconstrucionismo. A continuación analízase como o ambiente en que se desenvolveu Fraguas foi o das ideas de Nós. Por último reflexiónase sobre a Galicia e a identidade galega tal e como as concibe Antonio Fraguas.
Delivery, dose, outcomes and resource use of stroke therapy: the SSNAPIEST observational study
Authors: Gittins Matthew , Lugo-Palacios David , Vail Andy , Bowen Audrey , Paley Lizz , Bray Benjamin , Gannon Brenda , Tyson Sarah F 
Published: April 2020

BackgroundTherapy is key to effective stroke care, but many patients receive little.ObjectivesTo understand how stroke therapy is delivered in England, Wales and Northern Ireland, and which factors are associated with dose, outcome and resource use.DesignSecondary analysis of the Sentinel Stroke National Audit Programme, using standard descriptive statistics and multilevel mixed-effects regression models, while adjusting for all known and measured confounders.SettingStroke services in England, Wales and Northern Ireland.ParticipantsA total of 94,905 adults admitted with stroke, who remained an inpatient for > 72 hours.ResultsRoutes through stroke services were highly varied (> 800), but four common stroke pathways emerged. Seven distinct impairment-based patient subgroups were characterised. The average amount of therapy was very low. Modifiable factors associated with the average amount of inpatient therapy were type of stroke team, timely therapy assessments, staffing levels and model of therapy provision. More (of any type of) therapy was associated with shorter length of stay, less resource use and lower mortality. More occupational therapy, speech therapy and psychology were also associated with less disability and institutionalisation. Large amounts of physiotherapy were associated with greater disability and institutionalisation.LimitationsUse of observational data does not infer causation. All efforts were made to adjust for all known and measured confounding factors but some may remain. We categorised participants using the National Institutes of Health Stroke Scale, which measures a limited number of impairments relatively crudely, so mild or rare impairments may have been missed.ConclusionsStroke patients receive very little therapy. Modifiable organisational factors associated with greater amounts of therapy were identified, and positive associations between amount of therapy and outcome were confirmed. The reason for the unexpected associations between large amounts of physiotherapy, disability and institutionalisation is unknown. Prospective work is urgently needed to investigate further. Future work needs to investigate (1) prospectively, the association between physiotherapy and outcome; (2) the optimal amount of therapy to provide for different patient groups; (3) the most effective way of organising stroke therapy/rehabilitation services, including service configuration, staffing levels and working hours; and (4) how to reduce unexplained variation in resource use.FundingThis project was funded by the National Institute for Health Research (NIHR) Health Services and Delivery Research programme and will be published in full inHealth Services and Delivery Research; Vol. 8, No. 17. See the NIHR Journals Library website for further project information.