bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimal trajectory planning of industrial robot for improving positional accuracy
Authors: Rout Amruta , BBVL Deepak , Biswal Bibhuti B. , Mahanta Golak Bihari 
Published: October 2019

Purpose
The purpose of this paper is to improve the positional accuracy, smoothness on motion and productivity of industrial robot through the proposed optimal joint trajectory planning method. Also a new improved algorithm, i.e. non-dominated sorting genetic algorithm-II (NSGA-II) with achievement scalarizing function (ASF) has been proposed to obtain better optimal results compared to previously used optimization methods.

Design/methodology/approach
The end effector positional errors can be reduced by limiting the uncertainties of dynamic parameter variations like torque rate of joints. The jerk induced in robot joints due to acceleration variations are need to be minimized which otherwise induces vibrations in the manipulator that causes deviation in the encoders. But these lead to a vast increase in total travel time which affects the cost function of trajectory planning. Therefore, these three objectives need to be minimized individually so that an optimal trajectory path can be achieved with minimum positional error.

Findings
The simulation results have been obtained by running the proposed hybrid NSGA-II with ASF in MATLAB R2017a software. The optimal time intervals have been used to calculate jerk, acceleration and torque values for consecutive points on the trajectory path. From the simulation and experimental results, it can be concluded that the optimization technique could be used effectively for the trajectory planning of six-axis industrial manipulator in the joint space on the basis of minimum time-jerk-torque rate criteria.

Originality/value
In this paper, a new approach based on hybrid multi-objective optimization technique by combining NSGA-II with ASF has been applied to find the minimal time-jerk- torque rate joint trajectory of a six-axis industrial robot for obtaining higher positional accuracy. The results obtained from the execution of algorithm have been validated through experimentation using Kawasaki RS06L industrial robot for a particular defined path.
The interest rate sensitivity of output and prices with different levels of financial inclusion
Authors: Nguyen Huong Thi Truc 
Published: October 2019

PurposeThe purpose of this paper is to evaluate the interest rate (IR) sensitivity of output and prices in developing economies with different levels of financial inclusion (FI) for the period 2007Q1–2017Q4.Design/methodology/approachBy using the PCA method to construct an FI index for each country, the author divides the sample into two groups (high and low FI levels). Then, with panel vector autoregressions on per group estimated to assess the strength of the impulse response of output and prices to IR shock.FindingsThe findings show that the impact of an IR shock on output and inflation is greater in economies with a higher degree of FI.Practical implicationsThe finding indicates the link between FI and the effectiveness of IRs as a monetary policy tool, thereby helping Central banks to have a clearer goal of FI to implement their monetary policy.Originality/valueThis study emphasizes the important role of FI in the economy. From there, an FI solution is integrated into the construction and calculation of its impact on monetary policy, improving the efficiency of monetary policy transmission, contributing to price stability and sustainable growth.
Supporting integrated care in practice
Authors: Billings Jenny , Mikelyte Rasa , Coleman Anna , MacInnes Julie , Allen Pauline , Croke Sarah , Checkland Kath 
Published: October 2019

PurposeThe purpose of this paper is to investigate the perceptions of key informants on a national support programme for the development of new care models (NCM) in England (2015/2016–2017/2018). It focuses on the perceived facilitators and barriers affecting the development and implementation of the NCM programme and offers some insight into the role of national level support in enabling local integration initiatives.Design/methodology/approachA set of 29 interviews were carried out with a variety of respondents at the national level (including current and past programme leads, strategic account managers, advisors to the programme and external regulators) between October 2017 and March 2018, and analysed thematically.FindingsA set of facilitative elements of the programme were identified: the development of relationships and alliances, strong local and national leadership, the availability of expert knowledge and skills, and additional funding. Challenges to success included perceived expectations from the national Vanguard programme, oversight and performance monitoring, engagement with regulators, data availability and quality, as well as timetables and timescales. Crucially, the facilitators and challenges were found to interact in dynamic and complex ways, which resulted in significant tensions and ambiguities within the support programme.Research limitations/implicationsWhile the sample was drawn from a range of different senior players and the authors ensured a diverse sample associated with the NCM support programme, it inevitably cannot be complete and there may have been valuable perspectives absent.Originality/valueThe paper demonstrates that the analysis of facilitators and challenges with respect to the national support of implementation of integrated care initiatives should move beyond the focus on separate influencing factors and address the tensions that the complex interplay among these factors create.
Pretreatment of silk for digital printing: identifying influential factors using fractional factorial experiments
Authors: Faisal Saira , Tronci Aurelio , Ali Muhammad , Lin Long , Mao Ningtao 
Published: October 2019

PurposeThe purpose of this study is to identify the most influential factors affecting the printing properties and print quality of digitally printed silk fabrics in terms of colour strength and fixation percentage.Design/methodology/approachIn this study, five factors (concentration of thickener, concentration of urea, concentration of alkali, pH of pretreatment liquor and steaming duration) were investigated using a blocked 25−1fractional factorial experiment. The type of thickeners [polyacrylic acid and polyacrylamide (PAM)] were considered as a block.FindingsLinear models were obtained and statistically tested using both analysis of variance and coefficient of determination (R2), and they were found to be accurate at 90 per cent confidence level. It was revealed that concentration of alkali, concentrations of urea and pH of the pretreatment liquor had an increasing effect on colour strength, whereas concentration of thickener and steaming duration showed decreasing effect on colour strength of digitally printed silk fabrics. Furthermore, concentration of alkali, concentrations of urea had increasing effect on dye fixation percentage, whereas steaming duration showed decreasing effect on dye fixation percentage of digitally printed silk fabrics. In addition, PAM thickener based pretreatment recipe exhibited better printing properties for the digitally printing of silk fabrics.Originality/valueThe main influences and significant two-factor interactions were discussed in detail to gain a better understanding of the printing properties of digitally printed silk fabrics. The findings of this study are useful for further optimisation of pre- and post-treatment processes for digital printing of silk fabrics.
Engineering of surface properties of polypropylene nonwovens through oxygen plasma for enhanced color yield of pigment prints
Authors: Javid Amjed , Irshad Awais , Ashraf Munir , Rehman Abdur , Riaz Shagufta , Iqbal Kashif 
Published: October 2019

Purpose
This paper aims to evaluate the effect of plasma treatment on the performance and color strength of pigment printed polypropylene nonwovens fabrics.

Design/methodology/approach
Melt spun nonwoven fabrics have been treated with plasma discharge using oxygen as a reactive gas to activate their surfaces for better interfacial interactions. The untreated and plasma treated fabrics are printed using pigment print pastes to investigate the print properties of nonwoven fabrics that are correlated to surface characteristics. The printed fabrics are characterized through FTIR, color fastness to washing and rubbing, flexural rigidity and moisture management observations.

Findings
The fabrics treated with oxygen plasma exhibited higher wettability, higher overall moisture management capability, enhanced color strength and superior color fastness to washing. However, bending length and flexural rigidity have been increased.

Originality/value
This study offers promising findings regarding the surface activation of polypropylene nonwovens for enhanced performance, comfort and color fastness characteristics.
Physicochemical, microbiological, rheological, and sensory properties of yoghurts with new polysaccharide extracts from Lactarius volemus Fr. using three probiotics
Authors: Huang Yanyan , Zhao Shan , Yao Kun , Liu Dongmei , Peng Xin , Huang Juan , Huang Yongyao , Li Li 
Published: October 2019

Polysaccharide extracts (0.05 ~ 0.15% w/w) from Lactarius volemus Fr. were used as growth factors and were incorporated into three different probiotic yoghurts. Yoghurts with polysaccharide extracts had a significantly improved water‐retention capacity and reduced pH (P < 0.05). Polysaccharide extracts also significantly increased the viable count and essential amino acid content in the probiotic yoghurts (P < 0.05). The best sensory properties were achieved with the addition of 0.10% polysaccharide extracts. Our study suggests that polysaccharide extracts from L. volemus Fr. are a highly efficient growth factor for shortening the fermentation period and improving the quality of probiotic yoghurts.
Long‐term predictors of residual or recurrent cervical intraepithelial neoplasia 2–3 after treatment with a large loop excision of the transformation zone: a retrospective study
Authors: Fernández‐Montolí M‐E , Tous S , Medina G , Castellarnau M , García‐Tejedor A , de Sanjosé S 
Published: October 2019

ObjectiveTo assess the long‐term risk factors predicting residual/recurrent cervical intraepithelial neoplasia (CIN 2–3) and time to recurrence after large loop excision of the transformation zone (LLETZ).DesignRetrospective study.SettingColposcopy clinic.Population242 women with CIN 2–3 treated between 1996 and 2006 and followed up until June 2016.MethodsAge, margins, and high‐risk human papillomavirus (HR‐HPV) were estimated using Cox proportional hazard and unconditional logistic regression models. The cumulative probability of treatment failure was estimated by Kaplan–Meier analysis.Main outcome measureHistologically confirmed CIN 2–3, HR‐HPV, margins, age.ResultsCIN 2–3 was associated with HR‐HPV (HR = 30.5, 95% confidence interval [CI] = 3.80–246.20), age >35 years (HR = 5.53, 95% CI = 1.22–25.13), and margins (HR = 7.31, 95% CI = 1.60–33.44). HR‐HPV showed a sensitivity of 88.8% and a specificity of 80%. Ecto+/endocervical+ (16.7%), uncertain (19.4%) and ecto−/endocervical+ margins (9.1%) showed a higher risk of recurrence (odds ratio [OR] = 13.20, 95% CI = 1.02–170.96; OR = 15.84, 95% CI = 3.02–83.01; and OR = 6.60, 95% CI = 0.88–49.53, respectively). Women with involved margins and/or who were HR‐HPV positive had more treatment failure than those who were HR‐HPV negative or had clear margins (P‐log‐rank <0.001).ConclusionsHR‐HPV and margins seem essential for stratifying post‐LLETZ risk, and enable personalised management. Given that clear margins present a lower risk, a large excision may be indicated in older women to reduce the risk.Tweetable abstractAfter LLETZ for CIN 2–3, recurrences appear more often in women with positive HR‐HPV and involved margins and aged over 35.
Sperm Ultrastructure of corydalid Corydalus diasi Navás (Megaloptera, Neuropterida, Insecta) with phylogenetic considerations
Authors: Cuquetto‐Leite Lívia , Barbosa Aline , Salles Frederico Falcão , Mancini Karina Carvalho 
Published: October 2019

AbstractSpermatozoa of the Megaloptera Corydalus diasi (Corydalidae) showed a two‐layered acrosome, similar to Raphidioptera, but different from the acrosomal arrangement in Ascalaphidae, Coniopterygidae and Myrmeleontidae (Neuroptera families) and Sialidae (Megaloptera). Also, the acrosomal shape differs from both Raphidioptera and Neuroptera examined so far. The nucleus is cylindrical with condensed chromatin, resembling the sperm of Sialidae, Raphidioptera and Neuroptera. The transition region of C. diasi does not have the nucleus surrounded by centriolar microtubules, and thus, it differs from Sialidae, whose character has been previously considered a synapomorphy between Megaloptera and Raphidioptera. The flagella analysed here possess a 9 + 9 + 2 axoneme arrangement, two elongated circular mitochondrial derivatives and triangular accessory bodies, which are also reported in Raphidioptera. In summary, there are numerous sperm differences between Corydalidae and Sialidae, besides several characters shared between Corydalidae and Raphidioptera. However, several of these similarities appear to be plesiomorphisms rather than synapomorphies. Additionally, this is the first spermatic description for Corydalidae and the second for Megaloptera order. Therefore, considering the number of genres that comprise this family and the lack of spermiocladistics studies for Corydalidae, we recommended that new studies on the field should be performed to better understand the sperm pattern within the Corydalidae genus.
Lokale chirurgische Therapie des kutanen Plattenepithelkarzinoms: Defizite und Kontroversen in der Literatur
Authors: Breuninger Helmut , Eigentler Thomas , Häfner Hans‐Martin , Leiter Ulrike 
Published: October 2019

ZusammenfassungDer Einfluss der Primärexzision eines kutanen Plattenepithelkarzinoms auf die Prognose ist abhängig von den Risikofaktoren des Tumors, den chirurgischen Therapiemodalitäten und der histologischen Untersuchung.Im Zuge der AWMF‐Leitlinie Plattenepithelkarzinom wurden mittels DELBI‐Verfahren die aussagekräftigsten Leitlinien herangezogen. Dies waren die schottische, die kanadische und die gemeinsame Leitlinie der EDF, EADO und EORTC. Die Aufarbeitung der Primärliteratur dieser Leitlinien zu oben genannten Themen ergab 49 Studien und 9 Reviews. Keine Studie bot ein prospektives randomisiertes Schema, 19 enthielten prospektiv erhobene Daten, 30 retrospektive Daten. Insgesamt zeigten die Studien heterogene Ergebnisse. Es gab Diskrepanzen hinsichtlich der Wertigkeit der Risikofaktoren zur lokoregionären Progression, wie Entdifferenzierung, Desmoplasie und perineuraler Invasion, teils auch Tumordicke und chirurgischer Konsequenzen. Auch bei der histologischen Aufarbeitung ergaben sich Unterschiede. Die Literatur unterscheidet prinzipiell zwei Methoden der histologischen Aufarbeitung: die konventionelle Histologie mittels Lamellen (Brotlaib‐Histologie) und die lückenlose Randschnitt‐Histologie. Für Letztere zeigten die Studien niedrige Rezidivraten, aber auch niedrige Metastasierungsraten, eventuell infolge risikoärmerer Kollektive gegenüber ersterer Methode. Bei Publikationen zur Brotlaib‐Histologie fehlten genaue Angaben über die definitive Aufarbeitung. Ebenso fehlten verwertbare Angaben zum primären Resektionsabstand.Fazit: Die aktuelle Literatur ist uneinheitlich und insuffizient bezüglich der einzelnen prognostischen Faktoren und den Maßnahmen der chirurgischen Versorgung des kutanen Plattenepithelkarzinoms.
S3 guidelines: Epicutaneous patch testing with contact allergens and drugs – Short version, Part 1
Authors: Mahler Vera , Nast Alexander , Bauer Andrea , Becker Detlef , Brasch Jochen , Breuer Kristine , Dickel Heinrich , Drexler Hans , Elsner Peter , Geier Johannes , John Swen Malte , Kreft Burkhard , Köllner Arno , Merk Hans , Ott Hagen , Pleschka Silvia , Portisch Maria , Spornraft‐Ragaller Petra , Weisshaar Elke , Werfel Thomas , Worm Margitta , Schnuch Axel , Uter Wolfgang 
Published: October 2019

SummaryEpicutaneous patch testing is the diagnostic standard for the detection of allergic contact dermatitis. The present guidelines are aimed at residents and board‐certified physicians in the fields of dermatology and allergology as well as other medical specialties involved in establishing the indication for patch testing and its execution in patients with contact dermatitis and other forms of delayed‐type hypersensitivity. The target audience also includes other health care providers and insurance funds.Based on a systematic literature search and a formal consensus process (S3), the guidelines were developed by dermatologists in collaboration with pediatricians, occupational medicine physicians, nursing staff as well as patient representatives. The systematic methodological approach and appraisal of evidence upon which the recommendations are based are outlined in a separate method report that also contains evidence tables.The guidelines address general aspects of patch testing as well as medicolegal issues. The recommendations given relate to topics such as the indication for patch testing, informed patient consent, as well as the choice of test substances, test chambers and test site, duration of exposure, reading times and interpretation of test reactions. Furthermore, recommendations are provided with respect to endogenous and exogenous factors, specific patient groups (children, pregnant women, immunosuppressed individuals) as well as possible risks and adverse events associated with patch testing using contact allergens.Note: This publication is part 1 of the short version of the S3 guidelines for “Epicutaneous patch testing using contact allergens and drugs” (registry no. 013 – 018; date: March 20, 2019; valid until December 31, 2021). Part 2 of the short version will be published in the next issue. The long version of these guidelines can be accessed atwww.awmf.org. The method report is available as online publication (https://www.awmf.org/leitlinien/detail/ll/013‐018.html) and contains the evidence tables in its appendix.
Systemic sclerosis patients are at higher risk of hyperthyroidism and have a worse survival than those without hyperthyroidism: A nationwide population‐based cohort study
Authors: Akuka Aviram , Watad Abdulla , Comaneshter Doron , Cohen Arnon D. , Amital Howard , Bragazzi Nicola L. 
Published: October 2019

AbstractBackgroundA high prevalence of thyroid disorders has been reported in patients with autoimmune diseases. The link between hyperthyroidism and systemic sclerosis (SSc) has been relatively overlooked, and only a few studies utilizing small samples or case reports have been reported so far.ObjectivesTo investigate the association between SSc and hyperthyroidism.MethodsWe designed a case‐control study utilizing the medical database of the Clalit Health Services. Chi‐square and t tests were used for univariate analysis, and a logistic regression model was used for multivariate analysis.ResultsThe study included 2,431 SSc patients and 12,710 age‐ and sex‐matched controls. The mean age of the study population was 63.32 ± 18.06 years (median 66 years), and female‐to‐male ratio was 4.5:1. Age (P < .0001, OR 1.03 [95% CI 1.02‐1.04]), female sex (P = .0015, OR 1.86 [95% CI 1.27‐ 2.74]) and diagnosis of SSc (P = .0011, OR 1.81[95% CI 1.27‐2.58]) were all independently associated with hyperthyroidism. Patients with SSc and hyperthyroidism had 1.54‐fold increase of mortality rates during a mean follow‐up of 17 years than SSc patients without hyperthyroidism, even though at the Cox multivariate survival analysis, only age (HR 1.06 [95% CI 1.06‐1.07], P < .0001) and diagnosis of SSc (HR 2.35 [CI 2.06 to 2.69], P < .0001) resulted associated with a higher risk of mortality.ConclusionsHyperthyroidism is highly prevalent among SSc patients and can negatively impact on their survival rates. Therefore, a pre‐emptive screening may be warranted in all SSc patients. Further studies are needed to evaluate whether tight control and optimal treatment for hyperthyroidism may lead to a reduction of all‐cause mortality in patients with SSc.
Tri‐trophic interactions: bridging species, communities and ecosystems
Authors: Abdala‐Roberts Luis , Puentes Adriana , Finke Deborah L. , Marquis Robert J. , Montserrat Marta , Poelman Erik H. , Rasmann Sergio , Sentis Arnaud , van Dam Nicole M. , Wimp Gina , Mooney Kailen , Björkman Christer 
Published: October 2019

AbstractA vast body of research demonstrates that many ecological and evolutionary processes can only be understood from a tri‐trophic viewpoint, that is, one that moves beyond the pairwise interactions of neighbouring trophic levels to consider the emergent features of interactions among multiple trophic levels. Despite its unifying potential, tri‐trophic research has been fragmented, following two distinct paths. One has focused on the population biology and evolutionary ecology of simple food chains of interacting species. The other has focused on bottom‐up and top‐down controls over the distribution of biomass across trophic levels and other ecosystem‐level variables. Here, we propose pathways to bridge these two long‐standing perspectives. We argue that an expanded theory of tri‐trophic interactions (TTIs) can unify our understanding of biological processes across scales and levels of organisation, ranging from species evolution and pairwise interactions to community structure and ecosystem function. To do so requires addressing how community structure and ecosystem function arise as emergent properties of component TTIs, and, in turn, how species traits and TTIs are shaped by the ecosystem processes and the abiotic environment in which they are embedded. We conclude that novel insights will come from applying tri‐trophic theory systematically across all levels of biological organisation.
Parkinson disease
Authors: Balestrino R. , Schapira A.H.V. 
Published: October 2019

Parkinson disease (PD) is the most common neurodegenerative movement disorder. In Europe, prevalence and incidence rates for PD are estimated at approximately 108–257/100 000 and 11–19/100 000 per year, respectively. Risk factors include age, male gender and some environmental factors. The aetiology of the disease in most patients is unknown, but different genetic causes have been identified. Although familial forms of PD account for only 5%–15% of cases, studies on these families provided interesting insight on the genetics and the pathogenesis of the disease allowing the identification of genes implicated in its pathogenesis and offering critical insights into the mechanisms of disease. The cardinal motor symptoms of PD are tremor, rigidity, bradykinesia/akinesia and postural instability, but the clinical picture includes other motor and non‐motor symptoms. Its diagnosis is principally clinical, although specific investigations can help the differential diagnosis from other forms of parkinsonism. Pathologically, PD is characterized by the loss of dopaminergic neurons in the pars compacta of the substantia nigra and by accumulation of misfolded α‐synuclein, which is found in intra‐cytoplasmic inclusions called Lewy bodies. Currently available treatments offer good control of motor symptoms but do not modify the evolution of the disease. This article is intended to provide a comprehensive, general and practical review of PD for the general neurologist.