bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sizing complex networks
Authors: Zamora-López Gorka , Brasselet Romain 
Published: November 2019

AbstractAmong the many features of natural and man-made complex networks the small-world phenomenon is a relevant and popular one. But, how small is a small-world network and how does it compare to others? Despite its importance, a reliable and comparable quantification of the average pathlength of networks has remained an open challenge over the years. Here, we uncover the upper (ultra-long (UL)) and the lower (ultra-short (US)) limits for the pathlength and efficiency of networks. These results allow us to frame their length under a natural reference and to provide a synoptic representation, without the need to rely on the choice for a null-model (e.g., random graphs or ring lattices). Application to empirical examples of three categories (neural, social and transportation) shows that, while most real networks display a pathlength comparable to that of random graphs, when contrasted against the boundaries, only the cortical connectomes prove to be ultra-short.
The role of metal ion binding in the antioxidant mechanisms of reduced and oxidized glutathione in metal-mediated oxidative DNA damage
Authors: Eteshola Elias O U , Haupt Devin A , Koos Stephen I , Siemer Lee A , Morris Daniel L 
Published: November 2019

Abstract
The antioxidant activity of glutathione in its reduced (GSH) and oxidized (GSSG) forms against metal-mediated oxidative DNA damage was studied by monitoring production of 8-hydroxy-2′-deoxyguanosine (8-OH-dG) from calf-thymus DNA. GSH and GSSG were combined with Fe(ii) and Cu(ii) before and after addition of DNA to investigate the role of metal coordination in the antioxidant mechanism. The antioxidant behavior of GSH and GSSG was also compared to the known radical scavenger DMSO. GSH and GSSG lower oxidative DNA damage for Fe(ii) and Cu(ii) reactions. GSH only exhibited appreciable antioxidant behavior when combined with Fe(ii) prior to adding DNA, and GSH and GSSG were slightly more effective against Cu(ii)-mediated damage when combined with Cu(ii) prior to adding DNA. Raman spectra of GSH in the presence of Cu(ii) indicate that Cu(ii) oxidizes GSH and raises the possibility that the antioxidant activity of GSH against Cu(ii) reactions may be attributed to its ability to form GSSG. No evidence of GSH oxidation in the presence of Fe(ii) was observed. The fluorescent probe dichlorofluorescein diacetate (DCF-DA) shows that the presence of GSH (for Cu(ii) reactions) and GSSG (for Fe(ii) and Cu(ii) reactions) lowers levels of reactive oxygen species (ROS) in bulk solution. Overall, the results suggest that the mechanism of antioxidant activity for GSH and GSSG against Fe(ii) and Cu(ii)-mediated oxidative damage involves metal coordination, and isothermal titration calorimetry (ITC) studies of the Cu(ii)–GSSG system show an enthalpically favored complexation reaction with an apparent 1 : 1 stoichiometry.
The potential therapeutic effect for melatonin and mesenchymal stem cells on hepatocellular carcinoma
Authors: Mohamed Yasser , Basyony Mohamed A. , El-Desouki Nabila I. , Abdo Walied S. , El-Magd Mohammed A. 
Published: November 2019

Background/aim: Herein, we investigated the potential therapeutic effect of Melatonin (Mel) and/or mesenchymal stem cells (MSCs) on rat model of HCC.
Materials and Methods: Female mature rats were divided into 5 groups (n = 10/group): normal (Nor), HCC group intraperitoneally injected with 200 mg/kg DEN, and 3 treated groups; HCC + Mel (Mel) group given Mel intraperitoneally 20 mg/kg, twice a week, HCC + MSCs (MSCs) group intravenously injected by 1 × 106 cells, and HCC + MSCs (Mel +MSCs) group.
Results: Rats in HCC group showed most deteriorated effect in form of increased mortality and relative liver weight, elevated serum levels of ALT, AST, ALP, AFP and GGT in addition to increased pre-neoplastic nodules in liver tissues. Liver tissues of HCC group also exhibited lower level of apoptosis as indicated by decreased DNA fragmentation and expression of p53 caspase 9 and caspase 3 genes and increased PCNA immunoreactivity. Moreover, in this group the expression of IL6 and TGFβ1 genes was significantly upregulated. All these deleterious effects induced by DEN were reversed after administration of Mel and/ or MSCs with best improvement for the combined group (MSCs + Mel).
Conclusions: These findings reveal a better therapeutic effect for MSCs when given with Mel and we attribute this beneficial effect, at least in part, to triggering apoptosis and targeting inflammation in HCC. Therefore, combined treatment with Mel and MSCs is recommended to enhance the therapeutic potential against HCC.
Strahlenexposition bei der Herstellung von Radiopharmaka im nuklearmedizinischen Routinelabor, gemessen mit optisch stimulierten Lumineszenzdetektoren (OSL)
Authors: Wunderlich Gerd , Freudenberg Robert , Hartmann Holger , Herrling Petra , Kotzerke Jörg 
Published: November 2019

Zusammenfassung
Ziel Vor dem Hintergrund der neuen Strahlenschutzverordnung (StrlSchV) ist es sinnvoll, sich erneut einen Überblick über die Strahlenexposition des Personals bei Radiopharmakaherstellungen im radiopharmazeutischen Labor zu verschaffen. Dabei soll die Strahlenexposition im Bereich der Herstellung und Anwendung von Radiopharmaka erfasst werden, um Tätigkeiten mit hoher Exposition zu identifizieren und Arbeitsabläufe zu optimieren. In der Klinik und Poliklinik für Nuklearmedizin am Universitätsklinikum an der TU Dresden wurden dazu Messungen mit optisch stimulierten Lumineszenzdosimetern (OSL) durchgeführt.
Material und Methode Es wurden lichtgeschützte OSL-Dosimeter auf die Fingerkuppen von Daumen, Zeigefinger und Mittelfinger beider Hände und auf der Stirn platziert. Jedes OSL-Dosimeter war zuvor kalibriert worden. Untersucht wurde die Teilkörperexposition der Hände im Präparationslabor bei: 99mTc-Präparationen im Routinebetrieb, Aufziehen von Spritzen zur Radiosynoviorthese und von 90Y-Sirtex-Partikeln sowie Herstellung von 177Lu- und 68Ga-Präparaten.
Ergebnisse Es zeigte sich, dass die 99mTc-Präparationen zu einer relativ hohen Exposition führen aufgrund der Zahl der Präparationen und der Zahl an aufgezogenen Spritzen. Das Aufziehen der RSO-Spritzen führt in Abhängigkeit von der Zahl der zu füllenden Spritzen ebenfalls zu nennenswerter Handbelastung. Im Gegensatz dazu ist das Aufziehen der Sirtex-Partikel wenig belastend. Die Strahlenexposition bei 177Lu- und 68Ga-Präparationen hängt insbesondere vom Handling bei der Herstellung, der Verwendung von Modulen und der Art der Qualitätskontrolle ab. Bei der Ermittlung der Augenlinsenexposition wurden mit einer Ausnahme unkritische 0,02 mGy oder weniger gemessen.
Clinical assessment of depression and type 2 diabetes in Morocco: Economical and social components
Authors: Bensbaa Salma , Agerd Loubna , Boujraf Saïd , Araab Chadya , Aalouane Rachid , Rammouz Ismail , Ajdi Farida 
Published: November 2019

ABSTRACT
Background: The global prevalence of diabetes is increasing worldwide. In Morocco, diabetes and depression are major public health problems, requiring improvement in their care. Diabetes and depression are associated with morbidity and early mortality. This association contributes to raising the risk of the complications that occur, while causing higher suffering to patients, as also an increased cost toward healthcare. Aim: This study aims to assess the prevalence of depression in patients with type 2 diabetes (T2D), and identify the main risk factors for depression in this category of diabetic patients. Patients and Methods: Type 2 diabetic patients and older than 18 years of age were recruited. The exclusion criteria included being type 1 diabetic, pregnant woman, hospitalized patients, a history of neurological disorders, such as, stroke, infectious episidodes, and history of psychiatric disorders. The individual patient data was collected through individual and confidential interviews lasting 30 minutes, at the end of the diabetology consultation, by the same diabetologist, trained to use the psychometric scales that were needed. The Moroccan–Arabic version of the Beck diagnostic scale of depression was used. Patients assessed with depressive disorders were reviewed in a specialized psychiatric consultation. The statistical analysis was achieved by using SPSS package (version 17). We retained a threshold P value of 0.05. Settings and Design: A cross-sectional study was conducted that included adults with type 2 diabetes. The depression diagnosis was performed using the Arabic version of the Beck Depression scale. Statistical Analysis: We included 142 patients with type 2 diabetes, with an average age of 56.26 years. The prevalence of depression was 33.1%. The risk factors recognized for depression were, lack of social security, hypertension, and a history of type 2 diabetes of more than five years. Results and Conclusions: In this study, we have focused on the frequent association of ‘Type 2 diabetes and depression’ and the risk of mutual aggravation of both pathologies that might require multidisciplinary healthcare, as well as, improvement in the risk factors of depression through improved access to healthcare, with the extension of social security. The stability of the healthcare personnel involved in the treatment of both chronic diseases, including diabetes and hypertension screening, should also be considered for better management of psychiatric complications.
Unusual occurrence of supratentorial medulloepithelioma in a young female
Authors: Ramesh Andi Sadayandi , Anita Mahadevan , Jitender Saini , Somanna Sampath 
Published: November 2019

ABSTRACTMedulloepithelioma is an extremely rare PNET in late adolescence and adults with only two cases noted in literature. These are WHO grade IV tumors with dismal prognosis. Only few cases survived beyond 5 months. We report a rare case of supratentorial medulloepithelioma in a 17 year old girl. She had presented with right sided weakness, headache and vomiting. Imaging showed an enhancing mass lesion in left parietal region which undergone gross total resection. After surgery, her headache, vomiting and right sided weakness improved. On histopathology, the tumor had characteristic trabecular, ribbon and palisaded arrangement with brisk mitotic activity, necrosis and calcification. Immuno-histochemistry revealed positivity for Synaptophysin, Vimentin and EMA while GFAP was negative. MIB-1 labeling was very high. Patient received postoperative radiotherapy. On follow up after 14 months, she was clinically asymptomatic with no recurrence on imaging.
Spontaneous hemothorax associated with neurofibromatosis type I: A review of the literature
Authors: Pulivarthi Swaroopa , Simmons Byron , Shearen John , Gurram Murali Krishna 
Published: November 2019

ABSTRACTNeurofibromatosis is generally a benign disease, but has the potential for rare and fatal complications, such as spontaneous hemothorax. We report a case of massive hemothorax due to neurofibroma in a 49-year-old woman with neurofibromatosis type 1. The configuration of the radiological opacity and frank blood withdrawn on thoracentesis should suggest the diagnosis of hemothorax in a patient with neurofibromatosis. Surgical treatment for hemothorax is limited by arterial fragility and the prognosis is relatively poor. Any evidence of aneurysmal disease in the thoracic vessels should be aggressively managed percutaneously by coil embolization to prevent future rupture.
All-trans-retinoic acid–induced pseudotumor cerebri in acute promyelocytic leukemia
Authors: Anoop T. M. , Jain Nidhi , Nair Sreejith G. , Narayanan Geetha 
Published: November 2019

ABSTRACTAll-trans-retinoic acid is an integral part in the treatment strategy of acute promyelocytic leukemia (APL). Here we describe a case of pseudotumor cerebri associated with all-trans-retinoic acid (ATRA) during the induction therapy in an adult with acute promyelocytic leukemia (APL).
Olfactory region schwannoma: Excision with preservation of olfaction
Authors: Salunke Pravin , Patra Devi Prasad , Futane Sameer , Nada Ritambhara 
Published: November 2019

ABSTRACTOlfactory region schwannomas are rare, but when they occur, they commonly arise from the meningeal branches of the trigeminal nerve and may present without involvement of the olfaction. A 24 year old lady presented with hemifacial paraesthesias. Radiology revealed a large olfactory region enhancing lesion. She was operated through a transbasal with olfactory preserving approach. This manuscript highlights the importance of olfactory preservation in such lesions.
A Case Report Describing Three Cases of Challenging or Failed Intubation after Cervical Spine Surgery: A Peril of Early Extubation
Authors: Mishra Puneet , Mishra Kelly Louise , Palmer Cassandra , Robertson Amy 
Published: November 2019

AbstractPostoperative airway complications can be a common, yet perhaps underappreciated, complication in patients undergoing cervical spine surgery. Presented here are three cases in which patients experienced postoperative airway compromise, resulting in difficulty establishing a secure airway following cervical spine operations. Establishing factors that contribute to airway complications after cervical spine surgery can aid in early identification of high-risk patients to create an appropriate airway management strategy. Ultimately, the frequency of airway difficulty after removal of the endotracheal tube in patients undergoing cervical spine surgery should not be taken lightly.
Real-time probing of chirality during a chemical reaction
Authors: Baykusheva Denitsa , Zindel Daniel , Svoboda Vít , Bommeli Elias , Ochsner Manuel , Tehlar Andres , Wörner Hans Jakob 
Published: November 2019

Significance
Chiral molecules interact and react differently, depending on their handedness (left vs. right). This chiral recognition is the principle governing most biomolecular interactions, such as the activity of drugs or our perception of scents. In spite of this fundamental importance, a real-time (femtosecond) observation of chirality during a chemical reaction has remained out of reach in the gas phase. In the present work, we report this breakthrough with a seemingly unlikely technique: high-harmonic generation (HHG) in tailored intense near-infrared laser fields. Combining the transient-grating technique with HHG in counterrotating circularly polarized laser fields, we follow the temporal evolution of molecular chirality during a chemical reaction from the unexcited electronic ground state through the transition-state region to the final achiral products.
Relationships between perceived coach leadership, athletes’ use of coping and emotions among competitive table tennis players
Authors: González‐García Higinio , Martinent Guillaume 
Published: November 2019

AbstractThe aims of this study were to examine: (a) whether coach leadership behaviours predict athletes’ use of coping and (b) whether coping predicts athletes’ emotional outcomes in competition. A sample of 180 table tennis players (M age = 33.87; SD = 16.64; 149 men and 31 women) voluntarily participated in the study. A partial least square path modelling (PLS‐PM) approach was used to examine the relationships between the study variable. The results showed that: (a) coach democratic behaviour was significantly related to task‐oriented coping; (b) task‐oriented coping was significantly related to excitement and happiness; (c) distraction‐oriented coping was significantly related to anxiety, dejection and anger. As a whole, PLS‐PM results suggested that coach democratic behaviour could be the better style in relationship with positive coping and emotion outcomes in table tennis players.
Performance investigation of LabPET II detector technology in an MRI-like environment
Authors: Moghadam Narjes , Arpin Louis , Espagnet Romain , Bouchard Jonathan , Viscogliosi Nicolas , Lecomte Roger , Fontaine Réjean 
Published: November 2019

Abstract
The EMI-compatibility of the LabPET II detection module (DM) to develop a high-resolution simultaneous PET/MRI system is investigated. The experimental set-up evaluates the performance of two LabPET II DMs in close proximity to RF coils excited at three different frequencies mimicking the electromagnetic environments of 3 T, 7 T, and 9.4 T MRI scanners. A gradient coil, with switching frequency from 10 kHz to 100 kHz, also surrounds one of the DMs to investigate the effects of the gradient field on the individual detector performance, such as the baseline of the DC-voltage and noise level along with both the energy and coincidence time resolutions. Measurements demonstrate a position shift of the energy photopeaks (⩽9%) and a slight deterioration of the energy and coincidence time resolutions in the presence of electromagnetic interferences from the gradient and RF coils. The electromagnetic interferences cause an average degradation of up to ~50% of the energy resolution (in time-over-threshold spectra) and up to 18% of the timing resolution. Based on these results, a modified version of the DM, including a composite shielding as well as an improved heat pipe-based cooling mechanism, capable of stabilizing the temperature of the DM at ~40 °C, is proposed and investigated. This shielded version shows no evidence of performance degradation inside an MRI-like environment. The experimental results demonstrate that a properly shielded version of the LabPET II DM is a viable candidate for an MR-compatible PET scanner.
Batik Nusantara Pattern In Design Of Mathematical Learning Model For Elementary School
Authors: Purwoko R Y , Astuti E P , Arti M S , Widiyono Y 
Published: November 2019

Abstract
The focus of education is not only on skill development but also on character building. The purpose of this study is to produce a product of mathematical learning model that combines the mathematics and cultural values of batik Nusantara. The development model used in this research is ADDIE (Analysis, Design, Development, Implementation, and Evaluation). Development stage generates mathematics learning model using Batik Nusantara setting with the main product such as learning model book, student book, teacher book, syllabus, learning implementation plan, and student worksheet. In the final product, cultural values in the form of character building to students by learning process produce a very positive student response with a score of 86.6%. In addition, by expert assessment, test and non-test data collecting, and limited trials show that learning model is valid with practicality score of 3.90 and effectiveness score 3.93. The scores indicate that the student’s response to the learning model is positive and better maths learning outcomes. Base on the result, this learning model is said to be feasible to use.
What Kind Of Relationship Is Between Ki Ageng Suryomentaram And Ki Hadjar Dewantara? : Two Figures Of Indonesian Education
Authors: Gularso Dhiniaty , Sugito  , Zamroni  
Published: November 2019

Abstract
This research aims at revealing the relationship between Ki Ageng Suryomentaran (KAS) with Ki Hadjar Dewantara (KHD). This is library research in which the data were gained through documenting the books. The triangulation of the book resources was used as the technique of data analysis. The result of the research indicates that (1) KAS and KHD lived in the same era to prepare the independence day of Indonesia, (2) both of them were in the same society called as Kliwonan, in which KAS was the leader and KHD was the secretary, (3) both of them fully participated in education by sharing roles. KAS took care of the adults through Kawruh Jiwa consisting of Kawruh Pamomong, and KHD took care of children through Sistem Among in the Taman Siswa School. The relationship, concept, thought, history and spirit of struggle of those people are interesting to be studied comprehensively to fulfill each other to become theory, concept and practice in education which comes from Indonesia that is suitable with culture and Indonesian characters.
An Analysis of Student Satisfaction Level on Service and Facilities Quality Using Weighted Least
Authors: Dwipa Nendra Mursetya Somasih , Sunanti Titis 
Published: November 2019

Abstract
The present article aims to study the level of students satisfaction of PGRI Yogyakarta University towards service and facilities quality. To try and understand the factors which influence student satisfaction as well as consequences of it, this study test a weighted least squares model. This study investigate determinant and dominant factors of the students satisfaction and its characteristics. The data were collected through a questionnaire administered to 644 students of PGRI Yogyakarta University to investigate their perceptions of the universities services. A questionnaire containing 30 questions has been used for data collection. The data were analyzed using the descriptive technique and the weighted least sqares analysis. The measurement of the service quality is an important element to provide better, more efficient and more effective services. Spss Software and cronbach alpha index have been used for data analysis and reliability. The reliability factor should be improved first because it is dominant in determining the students’ satisfaction. Quality indicators constituting the reliability factor include classroom, library, laboratory, public area, and information system.
The results show that, by percentage, 2 indicator is in the very good category, only 5 indicators are in the good category, 9 indicators are in the fairly good category, and 14 indicators are in the poor category. The results indicate that the universities service quality needs to be improving. The results of the analysis show that five determinant factors of the students’ satisfaction include tangibles, reliability, responsiveness, assurance, and empathy. By the priority scale, the reliability factor should be improved first because it is dominant in determining the students’ satisfaction.
Nutritional Status and Its Impact on Academic Performance of Selected Grade 8 Students
Authors: Beredo  , Aceron Aubrey 
Published: November 2019

Abstract
This study aimed to determine the nutritional status, causes of malnutrition and its impact on the academic performance of Grade 8 Students with wasted and severely wasted BMI. The researcher used the descriptive – correlational research method which described the relationship between variables. Four (4) variables were used in this study such as poverty, health condition, eating habits, and illiteracy. The results showed that sometimes health condition and illiteracy are the contributing factors for malnutrition as evidenced by the average mean of 3.06 and 3.58 respectively. While most often, poverty and eating habits contributed to the causes of malnutrition. A negligible negative correlation existed between weight and academic performance based on the computed r value which was less than the tabular value of 0.349 at 5% level of significance. The obtained chi-square value between nutritional status and academic performance was found to be insignificant since the obtained chi-square value was less than the tabular value of 9.488 at 5% level of significance. Thus, the researcher recommends that continuing School-Based feeding program be strengthened. Further, it is also recommended to encourage the active involvement of parents, communities and local government in the implementation of intensified school nutrition program.