bluuebunny/crossref_metadata_2025_split huggingface dataset:
A PRESPECTIVE STUDY ON APOBEC PROTEIN FAMILY
Authors: GEJALAKSHMI S. , HARIKRISHNAN N. , KOMAL S. 
Published: November 2019

Apobec is an apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like" is a family of deaminases. It has two types of APOBEC enzymes n-terminal of apobec enzyme and C-terminal of APOBEC enzyme. N-terminal domain is catalytic domain and C-terminal domain is a pseudo catalytic domain. Pathogen and cellular genome undergo mutation by human DNA cytosine to uracil deaminases. Three subtypes of APOBEC3D. APOBEC3F, APOBEC3G and APOBEC3H restrict human deficiency virus-1. Two APOBEC enzymes are the sources of somatic mutagenesis in cancer cells that drive tumor evolution and manifest clinically as theraphy resistance. This review of the APOBEC family will focus on an open question in regulation, namely what role the interactions of these proteins with RNA have in editing substrate recognition or allosteric regulation of DNA mutagenic and host-defense activities.
ANTIBIOTICS UTILIZATION PATTERNS AND DIRECT COST IN AN EMERGENCY TREATMENT UNIT IN SRI LANKA
Authors: ABERATHNA ACHINI , MORRISSEY HANA , BALL PATRICK , ZAWAHIR SHUKRY 
Published: November 2019

Objective: Anecdotal evidence suggested that antibiotics are frequently used in the Emergency Treatment Units in Sri Lanka, mostly for the respiratory tract, soft tissue or urinary tract infections. This study aimed to describe the utilization patterns of antibiotics in terms of most common type, indication and associated direct cost in ETU at the Teaching Hospital Karapitiya, Sri Lanka.
Methods: In this study, utilization patterns and the direct cost of antibiotics in an emergency treatment unit was evaluated by checking the bed-head tickets of all patients admitted to the unit from 1/5/16 to 15/5/16. Out of the 414 bed-head tickets checked 156 patients were receiving antibiotic treatment. Socio-demographic characteristics were analyzed. The prices of antibiotics in SriLankan government hospitals were taken from the hospital medical supply division price list. Data were analyzed by Microsoft Excel™.
Results: In this study, 45.5% (out of 156 patients) were aged between 61-80years. The most used antibiotic was amoxicillin/clavulanic acid (18.1%) and clarithromycin (15.5%). Generic antibiotics were used for most patients (95.58%). Fixed-dose combinations were used in 18.5% of cases, including amoxicillin/clavulanic acid and piperacillin/tazobactam. The common indications for prescribing antibiotics were respiratory tract infections (31.2%) and soft tissues injuries (12.1%).
Conclusion: This study revealed that there is apparent overuse of antibiotics and reveals that antibiotic stewardship programme could reduce antibiotic use, antibiotic resistance, and cost. Improved understanding of the rationale for antibiotic use would contribute optimising their use. Further studies are needed to establish the extent of sub-optimal prescribing of antibiotics in Sri Lankan hospitals.
К проблеме обобщённых характеров
Authors: Кузнецов Валентин Николаевич , Матвеева Ольга Андреевна 
Published: November 2019

Проблема обобщённых характеров заключается в решении задачи Ю. В. Линника, поставленной им в 1949 году, относительно аналитического продолжения как целых функций на комплексную плоскость одного класса рядов Дирихле и в решении гипотезы Н. Г. Чудакова, выдвинутой им в 1950 году о том, что любой конечнозначный числовой характер, отличный от нуля почти на всех простых числах и имеющий ограниченную сумматорную функцию, является характером Дирихле. Позднее такие характеры получили название неглавных обобщённых характеров. Коэффициенты рядов Дирихле в задаче Ю. В Линника также определялись неглавными обобщёнными характерами.Кроме Ю. В. Линника и Н. Г. Чудакова решениями проблемы обобщённых характеров занимались такие известные математики как В. Г. Спринджук, К. А. Родосский, Б.~М.~Бредихин и многие другие, но проблема оставалась открытой.Последние годы авторы разработали аппроксимационный подход, основанный на приближении в правой полуплоскости комплексной плоскости функций, заданных рядами Дирихле, полиномами Дирихле, в задаче аналитического продолжения рядов Дирихле с мультипликативными коэффициентами. Ранее этот подход позволил авторам решить задачу Ю. В. Линника, а в данной работе приводится решение гипотезы Н. Г. Чудакова.
A BIOGEOGRAFIA E A TEMÁTICA DA DIVERSIDADE CULTURAL NA EDUCAÇÃO SUPERIOR: CONTRIBUIÇÕES DA ECOLOGIA DE SABERES NA FORMAÇÃO DE PROFESSORES(AS) DE GEOGRAFIA
Authors: Silva Junior Ivan De Matos e , Almeida Rosiléia Oliveira de 
Published: November 2019

A formação de professores(as) para a diversidade cultural tem sido uma prerrogativa curricular que vem sendo lembrada com a obrigatoriedade da Lei 11.645/08, que busca, por sua vez, dar conta da história e cultura afro-brasileira e indígena. Na Geografia, essa temática encontra aderência nos estudos da geografia humana, enquanto que na geografia física, especialmente na biogeografia, o tema da diversidade cultural não tem sido adotado a contento, por conta do seu comprometimento com hermenêuticas cientificistas, em que a dimensão cultural estabelece relação de sinonímia com a ideia de um homem universal, expressa geralmente a partir das ações antropogênicas. Desse modo, o presente artigo visa apresentar contribuições teóricas da ecologia de saberes para a formação de professores(as) de Geografia, no âmbito das temáticas biogeográficas referendadas na diversidade cultural. Diante desse contexto, o presente artigo que é um dos resultados de pesquisa que vendo sendo realizada em nível de doutoramento, constitui-se como uma reflexão teórico-empírica que emergiu durante ação extensionista envolvendo estudantes, egressos e professores(as) de Geografia e Biologia. Dentre alguns resultados do estudo, reconheceu-se que a biogeografia tem forte potencial em incorporar a temática da diversidade cultural, a partir do processo de reconhecimento e visibilização de saberes e experiências dos povos originários que apresentam formas particulares de compreensão do mundo vivo em sua dimensão espaço-temporal; ajuda na superação do cientificismo no ensino de biogeografia na formação inicial e continuada de professores(as), ao mesmo tempo que assinala a importância da afirmação desses saberes como forma de superação do epistemicídio e do etnocídio.
Realization of manipulating techniques in promotional internet-discourse on service industry
Authors: Морозова Янина Самвеловна , Morozova Yanina Samvelovna 
Published: November 2019

The article highlights the peculiarities of implementing advertising texts of European and domestic hotels in the Internet discourse. These texts are characterized by manipulation tactics and approaches: manipulation of images, ways of presenting information, speech manner influencing at the lexical level. Manipulation of images in advertising texts is realized by means of appeal to positive emotions, appeal to social attitudes, accentuation of attention, speculation in the right di-rection, creating a virtual tour, offering call information, receiving solidarity, receiving indications of authority and receiving binding. Manipulative tactics of information supply is realized by means
of composing topics by small portions, selection of information, excessive supply of information, mnemonic tactics of presenting information, “You”-approach, slogans, putting on the mask of the adviser.
Como nos movemos nos dois lados da fronteira – Reflexão sobre variação lexical entre o português e o galego
Authors: Carrilho Ana Rita , Vázquez Diéguez Ignacio 
Published: November 2019

A reflexão sobre o conceito de movimento remonta à filosofia grega pré-socrática, associada a outros conceitos como os de tempo, de mudança e metamorfose. É histórica a contenda entre Parménides (imobilidade) e Heráclito de Éfeso, para quem na natureza, na vida e na sociedade tudo é dinâmico. Mais tarde, Aristóteles sintetizou estas duas posições e o conceito de movimento, frequentemente associado a mudança e devir, torna-se num dos principais desafios colocados ao pensamento aristotélico. O filósofo traça uma teoria do movimento, dividindo-o em deslocamento no espaço (traslação), substância (geração), mudança quantitativa (aumento e diminuição) e mudança qualitativa (alteração). Neste sentido, estão lançadas as bases para a máxima tomista: Tudo o que se move é movido por alguma coisa.Do ponto de vista lexical, uma recolha (e respetiva análise) dos verbos que carregam o sema de movimento permitirá traçar um percurso da forma como o sujeito se relaciona desde sempre com tudo o que o rodeia, sendo ainda mais pertinente verificar a existência de pontos de contacto e de afastamento entre línguas como o galego e o português que partilham não só uma fronteira, como também uma história.
Effect of parameter selection on different topological structures for Particle Swarm Optimization algorithm
Authors: Peri Daniele 
Published: November 2019

Abstract
Particle Swarm Optimization is an evolutionary optimization algorithm, largely studied during the years: analysis of convergence, determination of the optimal coefficients, hybridization of the original algorithm and also the determination of the best relationship structure between the swarm elements (topology) have been investigated largely. Unfortunately, all these studies have been produced separately, and the same coefficients, derived for the original topology of the algorithm, have been always applied. The intent of this paper is to identify the best set of coefficients for different topological structures. A large suite of objective functions are considered and the best compromise coefficients are identified for each topology. Results are finally compared on the base of a practical ship design application.
The Role of Social Relationships in Children’s Active EFL Learning
Authors: Matrić Maja , Brumen Mihaela , Košir Katja 
Published: November 2019

Abstract
Our research aimed to investigate the relationship between the measures of satisfied need for relatedness (perceived academic and personal peer support and teacher-assessed social acceptance of the student) and measures of active English as a Foreign Language (EFL) (teacher-assessed and student self-assessed EFL engagement and EFL anxiety), as well as possible gender differences in an EFL setting. The research included 535 students and 11 teachers from rural primary schools in Slovenia. The predictive value of need for relatedness was the strongest for students’ emotional EFL engagement and teacher-assessed EFL engagement of the students, followed by students’ behavioral EFL engagement and EFL anxiety. Students who report higher peer support and are assessed as more socially accepted by their teachers experience higher engagement (self-assessed and teacher-assessed) and lower EFL anxiety. All measures of active learning, apart from anxiety, were higher for girls.
Latvian Electric Vehicle Fast Charging Infrastructure: Results of the First Year of Operation
Authors: Rubenis Aivars , Laizans Aigars , Zvirbule Andra 
Published: November 2019

Abstract
This article presents preliminary analysis of the Latvian national EV fast - charging network after the first year of operation. The first phase of Latvian national EV fast-charging network was launched in 2018 with 70 charging stations on the TEN-T roads and in the largest towns and cities. The article looks at the initial results, both looking at the total capacity utilization for individual charging stations, determining the hourly charging distribution; and to the utilization of the network as a whole. The results present that there is a very large dispersion of the data, most of the charging events happening in a few charging stations in and around the capital of Latvia. However, there have been charging events in all charging stations, even in the most remote ones. Even more skewed distribution was observed analyzing the charging habits of the EV users, with 10 % of users accounting for more than half of the charging events. This should be taken into account when considering applying the results for the future, expecting larger number of electric vehicles in Latvia.
Development Features of Heat Power Industry Legislation in Russia
Authors: Mednikova Ekaterina , Stennikov Valery , Postnikov Ivan , Penkovskii Andrey 
Published: November 2019

Abstract
In Russia, the legislative support for the construction and operation of heating systems is permanently developing and improving. The Federal law “On heat supply” adopted in 2010 is the basic and most important document that regulates the work of heating systems. Moreover, the country has more than 10 additional documents that regulate this industry, and a great number of documents that establish rules for building and operating energy systems. The paper presents the main documents that regulate the heat supply industry in the Russian Federation, and a brief description of the main stages of heating system life cycle and problems solved in each of them. Despite the national policy of energy conservation and energy efficiency enhancement, there are still problems related to heat supply management due to large extension, complexity and a variety of types and structures of the systems. The main cause of the poor heat supply efficiency in Russia is explained by a considerable change in the structure of heat loads that has occurred of late years, a decrease in the loading of the main generating equipment and heat networks, which amid other things is fostered by an increasing wear of the systems. Upgrading of generating capacities and heat networks is considered in the framework of long-term investment projects for their modernization and expansion. The obtained solutions are reflected in the Schemes of urban heat supply. This paper proposes solutions aimed at enhancing the effectiveness of decisions made in the field of heat supply. It formulates the proposals on organization and regulation of the activities of all the participants in heat supply in the stage of long-term planning of heating system expansion, because well-founded and rational planning of construction and expansion of the systems is a basis for their efficient operation.
Ecological Feasibility of Applying Technology in Recycling Garment and Knitwear Production
Authors: Kadnikova Olga , Altynbayeva Gulnara , Kuzmin Sergey , Aidarkhanov Arman , Toretayev Medet , Khabdullina Zauresh 
Published: November 2019

Abstract
The paper deals with the problem of processing garment and knitwear production by recycling garment and knitwear. In this research was made a comparative assessment of the methods for producing knitted fabric from recycled yarn using various technological auxiliary equipment for recycling. The author gives a qualitative and environmental-economic assessment of the developed technology for obtaining a cloth of recycled yarn.
Thermodynamic, Environmental and Economic Simulation of an Organic Rankine Cycle (ORC) for Waste Heat Recovery: Terceira Island Case Study
Authors: Rocha-Meneses Lisandra , Silva Jose Carlos , Cota Sandra , Kikas Timo 
Published: November 2019

Abstract
The aim of this study is to analyse from the thermodynamic, environmental and economic point of view an ORC for heat recovery from urban waste, using R245fa as a working fluid on the example of Terceira Island (Azores). The proposed ORC system includes two evaporators, two turbines, a condenser, a pump and a generator. The thermodynamic model is created using the Visual Basic programming language. In order to analyse the influence of pressure, temperature and mass flow on net output, efficiency, and mass flow rate of the power plant, the sensibility analysis is carried out. The results show that from the energetic point of view, urban waste recovery (using an ORC) could be a viable solution on Terceira Island, since the maximum net output produced from this system for a mass rate of 19 727 tonnes is 485 kW. The efficiency of the ORC is 25 %. Environmentally, the incineration of the urban waste produced on the island is a positive solution for these residues since it will reduce the amount of waste deposited in the landfill. However, this project is not economically viable. The losses estimated in this study exceed 500 000 EUR (per year).
Hubungan Antara Dukungan Sosial Keluarga dengan Penerimaan Diri Individu yang Mengalami Asma
Authors: Utami Ni Made Sintya Noviana , Widiasavitri Putu Nugrahaeni 
Published: November 2019

Asthma is an inflammatory disease caused by narrowing of the respiratory tract. This disease can not be cured but its relapse can be controled. It will provide physiological and psychological impact to individual with asthma. That individual hardly tends to accept his or her self when diagnosed with chronic disease. Family social support will be needed to cope with the hard situation faced by individual with asthma. According to that, researcher formulates the problem, is there relationship between family social support and self acceptance of individuals with asthma. This research uses quantitative approach with correlation method. Samples in this research are 105 people suffer from asthma in Sanjiwani Hospital, Gianyar, who were chosen by systematic random sampling. The data are collected by questionnaire. Validity test of items of the family social support questionnaire shows there are 5 invalid items and 27 valid items from 32 items, and its reliability coefficient is 0,896. Validity test of items of the self acceptance questionnaire shows there are 12 invalid items and 30 valid items from 42 items, and its reliability coefficient is 0,899. Data analysis by Pearson’s product moment. Found coefficient correlation in this research is 0,687 with p value 0,000. Thus, there is positive relationship between family social support and self acceptance of individuals with ashtma. Keywords: family social support, self acceptance
Perbedaan Stres Persiapan Hari Raya Galungan pada Ibu Rumah Tangga dan Ibu Bekerja yang Beragama Hindu di Denpasar
Authors: Hantosa Bagus Galih , Suarya Luh Made Karisma Sukmayanti 
Published: November 2019

Galungan is Hindu religious holy day in celebrating the triumph of dharma over adharma. In Galungan preparation, the mothers, housewives and working mothers, are the one who in charge to prepare all banten that needed on Galungan. Preparing Galungan’s banten was not an easy task because skill, knowledge and time are needed to prepare all the banten, that why this activity had potential to make stress among housewives and working mothers. This study aimed to discover the difference Galungan preparation’s stress between Hindus housewives and working mothers in Denpasar Sampling technique used in this research was simple random samplings that were 100 subjects consisting of 52 working and mothers and 48 housewives that lived in Denpasar area, that filled the scale of Galungan Preparation’s Stress that was made by stress aspect from pyshic, emotional, and concentration by Dr. Robert J. an Amberg, Cary Cooper, Alison Straw and Braham. From available 60 items, 55 items was declared dan 5 items fall with reliability value 0,974,. Method of analyzing data used in this research is the analysis of parametric t-test independet group. Results from test data analysis is that there is a significant value of p= 0.000 which indicates a significant stress difference between both group of Hindus housewives and working mothers, which was working mothers have more stress level than housewives when working on Galungan’s preparation. Keywords : Galungan, Stress, Working Mothers, Housewives
Hubungan Intensitas Keikutsertaan Hypnobirthing dengan Tingkat Kecemasan Ibu Hamil di Gianyar
Authors: Martalisa Winda , Budisetyani I Gusti Ayu Putu Wulan 
Published: November 2019

During the pregnancy, a mother has experienced a significant changes to the physiological function and their psychological that causing an anxiety. Pregnant women who experience excessive anxiety during pregnancy until the delivery would cause pain during childbirth and this must be addressed, namely pregnant women should have the peace that the birth process to be smooth. Many natural ways that can be used to help reduce maternal anxiety, one way is to follow the hypnobirthing techniques. There are a lot of natural ways that can be used to help them decreased their anxiety. One thing that can be done is following the hypnobirthing technique. The aim of this research is to observed the relationship of hypnobirthing participation intensity with the anxiety levels of pregnant woman. The subject of this research were 20 pregnant women who take the hypnobirthing techniques with a gestational age around 7-9 months in Gianyar. The sample were selected using total sampling method. The anxious scale of the subjects were pointing to the aspects that stated by Daradjat. The intensity of participation in hypnobirthing is accounted by present list. The method of analyzing data in this research was by using the spearman non-parametric analysis. This research uses unused and try out the validity of the results obtained from 0,270 to 0.738, while the value of reliability for (a = 0.908). The result of the test analysis data is, there was a significant nominal for p=0,001 (p<0,05) with coefficient correlation value it is -689. That coefficient correlation has indicated that there was a negative relation between the anxious variable, to the participation of hypnobirthing intensity. Therefore, the hypothesis (Ha) in this research was acceptable. That is, if the intensity of the routine participation hypnobirthing the anxiety level will decrease. Support of the role of fathers and families in the process of hypnobirthing is highly recommended for pregnant women in order to obtain better results. Keywords: pregnancy women, anxiety, hypnobirthing
Emosi dan Penggunaan Warna Dominan Pada Kegiatan Mewarnai Anak Usia Dini
Authors: Pratiwi Putu Yudari , Budisetyani I Gusti Ayu Putu Wulan 
Published: November 2019

This study aims to determine the emotion influence towards use of the dominant color on early childhood coloring activities and also see the influence of positive and negative emotions toward the dominant color that used. Emotions are a condition that involves physiological, psychological, and feelings to act, because of the stimulus received by the senses, will be response, and processed. Emotions can be divided into positive emotions consist of happiness, excitement, also surprise and negative emotions consist of anger, sadness, fear, and disgust. Colors can manifest emotions that felt by someone. Bright color associated with positive emotions, and the dark color associated with negative emotions. Dominant color is color that most widely used in one image area. To count the area of the color is using grid technique or square method. This study use quasi experimental design with treatment by subject. The sampling was 30 students from Tunas Mekar Sari Kindergarten that taken by purposive sampling technique. The data analysis methods are using Crosstabs function, Chi-Square Test, and Coefficient Contingency C. Data analysis and study result find there are three hypotheses received, those are the strong emotion influence towards use of the dominant color on early childhood coloring activities, the strong positive emotion influence towards use of the bright dominant color, also the very strong negative emotion influence towards use of the dark dominant color. Keywords: turnover intention, psychological contract violation, type A personality, bank employees