bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of surgical outcomes between integrated robotic and conventional laparoscopic surgery for distal gastrectomy: a propensity score matching analysis
Authors: Roh Chul Kyu , Choi Seohee , Seo Won Jun , Cho Minah , Choi Yoon Young , Son Taeil , Hyung Woo Jin , Kim Hyoung-Il 
Published: January 2020

AbstractThis study was aimed to compare the surgical outcomes between conventional laparoscopic distal gastrectomy (CLDG) and integrated robotic distal gastrectomy (IRDG) which used both Single-Site platform and fluorescence image-guided surgery technique simultaneously. Retrospective data of 56 patients who underwent IRDG and 152 patients who underwent CLDG were analyzed. Propensity score matching analysis was performed to control selection bias using age, sex, American Society of Anesthesiologists score, and body mass index. Fifty-one patients were selected for each group. Surgical success was defined as the absence of open conversion, readmission, major complications, positive resection margin, and inadequate lymph node retrieval (<16). Patients characteristics and surgical outcomes of IRDG group were comparable to those of CLDG group, except longer operation time (159.5 vs. 131.7 min; P < 0.001), less blood loss (30.7 vs. 73.3 mL; P = 0.004), higher number of retrieved lymph nodes (LNs) (50.4 vs. 41.9 LNs; P = 0.025), and lower readmission rate (2.0 vs. 15.7%; P = 0.031). Surgical success rate was higher in IRDG group compared to CLDG group (98.0 vs. 82.4%; P = 0.008). In conclusion, this study found that IRDG provides the benefits of higher number of retrieved LNs, less blood loss, and lower readmission rate compared with CLDG in patients with early gastric cancer.
Identification, functional prediction, and key lncRNA verification of cold stress-related lncRNAs in rats liver
Authors: Ji Hong , Niu Chunyang , Zhan Xuelong , Xu Jing , Lian Shuai , Xu Bin , Guo Jingru , Zhen Li , Yang Huanmin , Li Shize , Ma Li 
Published: January 2020

AbstractCold stimulation reduces the quality of animal products and increases animal mortality, causing huge losses to the livestock industry in cold regions. Long non-coding RNAs (lncRNAs) take part in many biological processes through transcriptional regulation, intracellular material transport, and chromosome remodeling. Although cold stress-related lncRNAs have been reported in plants, no research is available on the characteristic and functional analysis of lncRNAs after cold stress in rats. Here, we built a cold stress animal model firstly. Six SPF male Wistar rats were randomly divided to the acute cold stress group (4 °C, 12 h) and the normal group (24 °C, 12 h). lncRNA libraries were constructed by high-throughput sequencing (HTS) using rat livers. 2,120 new lncRNAs and 273 differentially expressed (DE) lncRNAs were identified in low temperature environments. The target genes of DElncRNA were predicted by cis and trans, and then functional and pathway analysis were performed to them. GO and KEGG analysis revealed that lncRNA targets were mainly participated in the regulation of nucleic acid binding, cold stimulation reaction, metabolic process, immune system processes, PI3K-Akt signaling pathway and pathways in cancer. Next, a interaction network between lncRNA and its targets was constructed. To further reveal the mechanism of cold stress, DElncRNA and DEmRNA were extracted to reconstruct a co-expression sub-network. We found the key lncRNA MSTRG.80946.2 in sub-network. Functional analysis of key lncRNA targets showed that targets were significantly enriched in fatty acid metabolism, the PI3K-Akt signaling pathway and pathways in cancer under cold stress. qRT-PCR confirmed the sequencing results. Finally, hub lncRNA MSTRG.80946.2 was characterized, and verified its relationship with related mRNAs by antisense oligonucleotide (ASO) interference and qRT-PCR. Results confirmed the accuracy of our analysis. To sum up, our work was the first to perform detailed characterization and functional analysis of cold stress-related lncRNAs in rats liver. lncRNAs played crucial roles in energy metabolism, growth and development, immunity and reproductive performance in cold stressed rats. The MSTRG.80946.2 was verified by network and experiments to be a key functional lncRNA under cold stress, regulating ACP1, TSPY1 and Tsn.
The protective effects of enriched citrulline fermented milk with Lactobacillus helveticus on the intestinal epithelium integrity against Escherichia coli infection
Authors: Ho Sze Wing , El-Nezami Hani , Shah Nagendra P. 
Published: January 2020

AbstractThis study examined the protective effects of citrulline enriched-fermented milk with live Lactobacillus helveticus ASCC 511 (LH511) on intestinal epithelial barrier function and inflammatory response in IPEC-J2 cells caused by pathogenic Escherichia coli. Five percent (v/v) of fermented milk with live LH511 and 4 mM citrulline (5%LHFM_Cit-4mM) significantly stimulated the population of IPEC-J2 cells by 36% as determined by MTT assay. Adhesion level of LH511 was significantly increased by 9.2% when incubated with 5%LHFM_Cit-4mM and 5%LHFM_Cit-4mM reduced the adhesion of enterohemorrhagic (EHEC) and entero-invasive (EIEC) E. coli in IPEC-J2 cells by 35.79% and 42.74%, respectively. Treatment with 5%LHFM_Cit-4mM ameliorated lipopolysaccharide (LPS) from E. coli O55:B5 induced activated inflammatory cytokines expression (TNF-α, IL-6 and IL-8) and concentration (IL-6 and IL-8) and early apoptosis. It restored the transepithelial electrical resistance (TEER) and regulated the expression and distribution of tight junction (TJ) proteins (zonula occluden-1 (ZO-1), occludin and claudin-1), toll-like receptors (TLRs) (TLR2 and TLR4) and negative regulators of TLRs signalling pathway (A20 and IRAK-M). In conclusion, our findings suggested that 5%LHFM_Cit-4mM might have the positive effects on improving and maintaining the intestinal epithelial cell integrity and inflammatory response under both normal and pathogenic LPS-stimulated conditions.
Assessment of Tongue Position and Laryngeal Height in Two Professional Voice Populations
Authors: Hosbach-Cannon Carly Jo , Lowell Soren Y. , Colton Raymond H. , Kelley Richard T. , Bao Xue 
Published: January 2020

Purpose
To advance our current knowledge of singer physiology by using ultrasonography in combination with acoustic measures to compare physiological differences between musical theater (MT) and opera (OP) singers under controlled phonation conditions. Primary objectives addressed in this study were (a) to determine if differences in hyolaryngeal and vocal fold contact dynamics occur between two professional voice populations (MT and OP) during singing tasks and (b) to determine if differences occur between MT and OP singers in oral configuration and associated acoustic resonance during singing tasks.

Method
Twenty-one singers (10 MT and 11 OP) were included. All participants were currently enrolled in a music program. Experimental procedures consisted of sustained phonation on the vowels /i/ and /ɑ/ during both a low-pitch task and a high-pitch task. Measures of hyolaryngeal elevation, tongue height, and tongue advancement were assessed using ultrasonography. Vocal fold contact dynamics were measured using electroglottography. Simultaneous acoustic recordings were obtained during all ultrasonography procedures for analysis of the first two formant frequencies.

Results
Significant oral configuration differences, reflected by measures of tongue height and tongue advancement, were seen between groups. Measures of acoustic resonance also showed significant differences between groups during specific tasks. Both singer groups significantly raised their hyoid position when singing high-pitched vowels, but hyoid elevation was not statistically different between groups. Likewise, vocal fold contact dynamics did not significantly differentiate the two singer groups.

Conclusions
These findings suggest that, under controlled phonation conditions, MT singers alter their oral configuration and achieve differing resultant formants as compared with OP singers. Because singers are at a high risk of developing a voice disorder, understanding how these two groups of singers adjust their vocal tract configuration during their specific singing genre may help to identify risky vocal behavior and provide a basis for prevention of voice disorders.
Exploring Input Parameters in an Expressive Vocabulary Treatment With Late Talkers
Authors: Alt Mary , Mettler Heidi M. , Erikson Jessie A. , Figueroa Cecilia R. , Etters-Thomas Sarah E. , Arizmendi Genesis D. , Oglivie Trianna 
Published: January 2020

Purpose
The aims of this study were (a) to assess the efficacy of the Vocabulary Acquisition and Usage for Late Talkers (VAULT) treatment and (b) to compare treatment outcomes for expressive vocabulary acquisition in late talkers in 2 conditions: 3 target words/90 doses per word per session versus 6 target words/45 doses per word per session.

Method

We ran the treatment protocol for 16 sessions with 24 primarily monolingual English-speaking late talkers. We calculated a
d
score for each child, compared treatment to control effect sizes, and assessed the number of words per week children acquired outside treatment. We compared treatment effect sizes of children in the condition of 3 target words/90 doses per word to those in the condition of 6 target words/45 doses per word. We used Bayesian repeated-measures analysis of variance and Bayesian
t
tests to answer our condition-level questions.

Results
With an average treatment effect size of almost 1.0, VAULT was effective relative to the no-treatment condition. There were no differences between the different dose conditions.

Discussion
The VAULT protocol was an efficacious treatment that has the potential to increase the spoken vocabulary of late-talking toddlers and provides clinicians some flexibility in terms of number of words targeted and dose number, keeping in mind the interconnectedness of treatment parameters.

Supplemental Material

https://doi.org/10.23641/asha.11593323
Überprüfung der Faktorenstruktur einer deutschen
Fragebogenversion der Behavioral Pathology in Alzheimerʼs Disease
Scale
Authors: Sittler Mareike Christina , Meichsner Franziska , Wilz Gabriele 
Published: January 2020

ZusammenfassungZiel der Arbeit war die Untersuchung der Faktorenstruktur einer deutschen
Fragebogenversion der Behavioral Pathology in Alzheimerʼs Disease Scale
(BEHAVE-AD), welche Verhaltensauffälligkeiten unabhängig von
kognitiven Symptomen bei Menschen mit Demenz (MmD) erfasst. Die theoretisch
beschriebene 7-Faktoren-Lösung der BEHAVE-AD wurde noch nicht
zufriedenstellend für eine deutsche Fragebogenversion
überprüft. Daher wurde dies in der vorliegenden Studie
über eine konfirmatorische Faktorenanalyse vorgenommen. Es wurden die
Einschätzungen von 322 pflegenden Angehörigen von MmD
bezüglich der Verhaltensauffälligkeiten ihres an Demenz
erkrankten Angehörigen analysiert. Die 7 Faktoren der Originalversion im
Interviewformat (paranoide und wahnhafte Vorstellungen, Halluzinationen,
Aktivitätsstörungen, Aggressivität, Störungen im
Tagesrhythmus, affektive Störungen sowie Ängste und Phobien)
konnten in der deutschsprachigen Fragebogenversion der BEHAVE-AD nicht
bestätigt werden. Eine anschließend durchgeführte
explorative Faktorenanalyse (N=118) weist auf eine
4-Faktoren-Lösung hin, welche sich in die Kategorien Paranoide Ideen und
Aggressivität, Halluzinationen und Agitiertheit, Ängste und
Phobien und Affektive Störungen aufteilen lässt.
Effekte von Medical Flossing bei Patienten mit Schulterbeschwerden – Randomisierte kontrollierte Pilotstudie
Authors: Wienke Alisa Katharina , Thiel Christian , Kopkow Christian 
Published: January 2020

Zusammenfassung
Hintergrund Schultererkrankungen mit Schmerzen und/oder Bewegungseinschränkungen sind die dritthäufigste physiotherapeutische Diagnosegruppe in Deutschland. Mittels Medical Flossing sollen durch Bewegung unter starker Kompression von Gewebe u. a. diese Symptome verbessert werden.
Ziel Machbarkeit und Prüfung einer Evaluation der Anwendung von Medical Flossing im Praxisalltag hinsichtlich der Belastung und Sicherheit von Patienten sowie der standardisierten Umsetzbarkeit. Generierung von Daten für zukünftige Fallzahlkalkulationen. Dafür werden Effekte und Nebenwirkungen von Medical Flossing bei Patienten mit Schmerzen und/oder Bewegungseinschränkungen im Bereich des Schultergelenks evaluiert.
Methode Die Teilnehmer der Studie erhielten fünf physiotherapeutische Behandlungen, die um eine Behandlung mit Medical Flossing oder mit Sham-Flossing ergänzt wurden. Primäres Outcome war die Funktion der oberen Extremität anhand des Disabilities of the Arm, Shoulder and Hand (DASH), sekundäre Outcomes waren u. a. das Schmerzniveau anhand der Numeric Rating Scale (NRS), das Bewegungsausmaß (ROM) und das Auftreten von Nebenwirkungen. Die Gründe für die Ablehnung einer Studienteilnahme wurden formlos erfasst.
Ergebnisse Insgesamt wurden zwölf Teilnehmer in die Studie eingeschlossen. Weitere Personen haben die Teilnahme aufgrund von Vorbehalten gegenüber der Behandlungsmethode und des zusätzlichen Zeitaufwands durch die Datenerhebung abgelehnt. Funktion und Symptome wurden durch beide Behandlungsformen im Prä-Post-Vergleich positiv beeinflusst (DASH, max. NRS, ROM), statistisch signifikante Gruppenunterschiede existierten nicht. Bei allen Teilnehmern traten Nebenwirkungen auf, besonders Schmerzen und Hautveränderungen. Ernsthafte Symptome wie Kurzatmigkeit wurden vereinzelt in der Interventionsgruppe (IG) angegeben.
Schlussfolgerung Funktion und Symptome wurden durch beide Behandlungsformen positiv beeinflusst, mit einer in Teilbereichen höheren klinischen Wirksamkeit des Sham-Flossings (DASH, max. NRS). Weiterführend sollten der spezifische Effekt des Medical Flossings und das Verhältnis von Wirkung und Nebenwirkung unter Einbezug der Zugstärke der Flossinganlage kritisch untersucht werden. Zudem könnte die Anzahl der Erhebungsinstrumente (funktionelle Armbewegungen, Goniometermessung) reduziert werden, um die Rekrutierung von Patienten zu erleichtern.
Scarless platysmaplasty for platysmal bands
Authors: Shiffman Melvin A. , Mirrafati Sid 
Published: January 2020

ABSTRACTTransection of plastysmal bands has required a surgical approach that leaves scars and limits patient activities for a period of time. The author has developed a simple method to transect the platysmal bands under local anesthesia without resorting to skin incisions. The transection is performed with the use of a Vicryl ® suture that is inserted through the skin, around the platysmal band, and then out through the original entry point. A back and forth motion of the suture cuts through the band.
Radial, renal and craniofacial anomalies: Baller-Gerold syndrome
Authors: Murthy Jyotsna , Babu Ramesh , Ramanan padasani Venkat 
Published: January 2020

ABSTRACTthe baller-gerold syndrome is a rare syndrome with very few cases published in literature. craniosynostosis and radial aplasia are striking features, easy to diagnose. however, there are many differential diagnoses. often, the question raised is whether the baller-gerald syndrome is a distinct entity. we report a patient with findings of craniosynostosis and radial aplasia consistent with the diagnosis of the baller-gerold syndrome. genotypic heterogeneity could possibly underlie the phenotypic variability exhibited by these cases.
Opioid system is necessary but not sufficient for antidepressive actions of ketamine in rodents
Authors: Klein Matthew E. , Chandra Joshua , Sheriff Salma , Malinow Roberto 
Published: January 2020

SignificanceKetamine, an NMDA receptor antagonist, has generated intense excitement as a therapy for treatment-resistant depression. However, ketamine and its metabolites can act on a wide range of targets, including opioid receptors, which has raised concerns. Using behavioral and cellular assays in rodents, we find that blocking opioid function prevents the antidepressant-like effects of ketamine. However, in contrast to ketamine, administration of a µ-opioid agonist is hedonic and ineffective on anhedonia/avolition. Furthermore, ketamine’s cellular actions are both mimicked and occluded by an NMDAR antagonist but not by a µ-opioid agonist. These results suggest that ketamine does not act as a μ-opioid agonist, but functional μ-opioid receptors are permissive for the antidepressant effects of ketamine.
Evolution of the International System of Units: considering the challenge of user adoption
Authors: Brown Richard J C 
Published: January 2020

Abstract
This discussion considers the challenge of making amendments to the International System of Units (SI) in terms of the varying levels of adoption of these amendments by users of the SI. It categorises possible amendments along two scales. First, whether these are changes or additions to the SI; and second whether these amendments are optional or compulsory. Where amendments fall on these two scales gives an indication of whether they are low-risk or high-risk actions, in terms of their likely adoption by users of the SI and the confusion that lack of adoption might cause. Proposed amendments to the SI of current interest are considered with respect to this framework.
Preliminary study on the online reprocessing and refueling scheme for SD-TMS reactor
Authors: Ashraf O , Tikhomirov G V 
Published: January 2020

Abstract
The Single-fluid Double-zone Thorium Molten Salt reactor (SD-TMSR) has a promising future. Inherent safety, liquid fuel, and possibility of online reprocessing and refueling are unique potentials of the SD-TMSR. In the present study, the Monte Carlo code Serpent2 has been chosen to model the full core of the SD-TMSR. In addition, online reprocessing and refueling has been modeled based on subroutine provided by Serpent2. During the burnup time (10 years), the total mass of the fuel inside the core has been checked and found to be almost constant. Furthermore, we controlled the reactivity by adjusting the feed rate of fissile and/or fertile materials. The change of Keff, breeding ratio, Th and U-233 refill rates with burn-up time have been investigated. Additionally, the build-up of U-233 during 10 years has been calculated.
Evaluation of neutron activation of intermetallic matrices for dispersive nuclear fuel obtained by SH-synthesis
Authors: Balachov M.M. , Dolmatov O.Yu. , Kuznetsov M.S. , Kostyuchenko K.S. , Pimenov N.O. , Permikin A.A. 
Published: January 2020

Abstract
The paper describes a technique for obtaining intermetallic matrix materials based on Zr-Al and Ni-Al systems for dispersive nuclear fuel. This type of fuel is planned to be used in existing and future high-temperature nuclear reactors. Physical and mathematical modelling of the process of activation of matrices by neutron radiation showed that upon reaching the value of thermal neutron fluence of the order of 2.76⋅1021 n⋅cm−2, the activity of Zr-Al and Ni-Al matrices was 1.3 ⋅ 1010 and 0.2⋅1010 Bq/g, respectively. The analysis showed that in terms of exposure of irradiated fuel it is preferable to use a matrix based on the zirconium-aluminium system.
Application of pulsed heating in technologies of thermal-cycle processing of steel
Authors: Kozyr’ I.G. , Komolikov A.S. 
Published: January 2020

Abstract
In work features of application of concentrated streams of energy in technologies of thermal-cycle processing of metal products are considered. Examples of application of currents of high frequency at thermal-cycle processing are given. It is shown that application of concentrated streams of energy significantly reduces processing time, increases energy efficiency and allows receiving especially fine structure in the surface layers.
Determination of Effective Temperature at in-pile Study of Nuclear Fuel
Authors: Belendryasova E G , Panasenko R A , Tutnov I A , Anufriev B F , Maksimkin A I 
Published: January 2020

Abstract
In this work we describe the method to calculate the creep rate of uranium-gadolinium oxide fuel through the effective temperature of fuel samples. Effective temperature characterizes the creep rate with uneven temperature distribution during operation of fuel. Modern modeling technologies presented in ANSYS software were used to calculate the effective temperature. The calculations are compared with measures from in-pile experiments. The results of this work are extremely important for the licensing of new type of nuclear fuel.
Investigation of the elastic modulus and internal friction temperature dependences for the fuel rods by the resonance method tested by the modernized high-temperature device in hot cell
Authors: Moshev A A , Rodko I I , Martynenko S P , Martynenko S S , Ableyev A N , Berestov A V , Yudin I A , Gerasimov D Yu 
Published: January 2020

Abstract
using the modernized high-temperature installation, the elastic characteristics and internal friction of the fuel rod shells were investigated in hot cell in order to update computer codes for WWER-1000 fuel rods. The elastic characteristics of the shell are analytically described and obtained a numerical shape factor of the first longitudinal frequency is calculated. There is description of new measuring units that provide data gathering by automatic or half-automatic mode. The elastic modulus and internal friction temperature dependences are determined by application of high-temperature modernized device that provides carrying out experiments at a temperature of 1160 K. Obtained effect could be interpreted by the crushing of the structure of the material.
Optical properties of nanopatch antennas based on plasmonic nanoparticles and ruthenium complex
Authors: Gritsienko A V , Kurochkin N S , Vitukhnovsky A G , Eliseev S P 
Published: January 2020

Abstract
In this work, a significant reduction (up to 7 ns) of the excited states lifetime of the Ru dye (with a decay time of 850 ns) in an inhomogeneous «aluminium – silver nano-prism system (nano-patch antenna, NPA)», as well as an increase in the photoluminescence emitter to 2-3 times. The increase in the spontaneous emission rate of this substance is caused by the Purcell effect. The Purcell coefficient for the emitter in the cavity with hexagonal silver particles was 120. This decrease in the spontaneous emission decay time in the nano-patch antenna configuration is associated with an increase in the local density of photon states in the plasmon resonator, which increases the probability of a spontaneous transition from the excited state of the emitter. The results obtained by shortening the spontaneous emission time and increasing the intensity of the emitter radiation in a nano-patch antenna show possible prospects for using quantum dots and individual molecules with shorter luminescence times in nano-patch antennas. Such nano-patch antennas can form the basis for creating compact high-speed optical devices. Modeling in the mathematical package Comsol Multiphysics showed that the maximum values of the Purcell factors can exceed 104 in the NPA.
Experimental study of cavity length influence on lasing characteristics Q-Switched Nd:YLF laser
Authors: Koromyslov A.L. , Tupitsyn I.M. , Cheshev E.A. 
Published: January 2020

Abstract
The influence of the resonator configuration on the temporal characteristics of Nd: YLF crystals laser generation in the region of frequency degeneracy of the transverse modes of a resonator operating in the Q-Switch mode is studied. It is shown that in the degeneracy regions, the pulse duration stretches, while the peak pulse amplitude and the pulse repetition period decrease.