bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interações atmosfera-terra-oceano e suas repercussões na precipitação média registrada no leste da Região Nordeste do Brasil
Authors: Diniz Marco Túlio Mendonça , Souza Rosemeri Melo e 
Published: January 2020

O texto trata de explicar diferenciações climáticas existentes no leste da Região Nordeste do Brasil motivadas por fenômenos de circulação atmosférica local, influenciados pelas diferenças de pressão atmosférica no estado médio da atmosfera, atentando para as interações atmosfera-terra-oceano na área. Foram realizadas revisão de literatura, análise e interpretação de imagens de satélite e das normais climatológicas da área. Foi identificado que os fenômenos de brisa terra-mar e diferenças locais nos contrastes barométricos oceano-terra são responsáveis por importantes diferenciações climáticas na área. Esse trabalho de Geografia em escala Regional preencheu uma lacuna no conhecimento científico identificada desde a década de 1970.
Palavras-chave: Geografia Regional, Climatologia Regional, Litoral do Nordeste, Costa dos Recifes.
Evolução das vantagens comparativas na exportação de flore: Comparativo de São Paulo e Ceará4)
Authors: Santos José Márcio , Lima Neve Ranielle Fernanda 
Published: January 2020

O Brasil vem aumentando cada vez mais a sua participação no mercado mundial de flores. No Ceará, a floricultura ganha impulso a partir da década de 1990. Por sua vez, São Paulo, tem a maior produção de flores para exportação do país. Desta forma, surge o questionamento acerca do comportamento do segmento no mercado de exportação de flores. Assim este trabalho tem por objetivo geral analisar de forma equiparativa a evolução das vantagens comparativas dos estados do Ceará e São Paulo no comércio mundial de flores entre 1997 a 2014, A metodologia consiste no cálculo do Índice de Vantagem Comparativa Revelada de Vollrath. A base de dados foi obtida do MDIC/SECEX com informações sobre receita e quantidades exportadas da floricultura dos dois estados exportadores. Os resultados mostram que no final da década de 1990 o Ceará, até então, não era considerado um estado produtor competitivo. Contudo, a partir dos anos 2000, o mesmo avança a sua participação em relação aos demais estados brasileiros exportadores desse segmento, chegando à posição de segundo lugar em exportações totais de flores, ficando somente atrás de São Paulo que é considerado o primeiro exportador desse segmento.ABSTRACT Brazil has increased more and more to your participation in the world market. Historically, the State of São Paulo is the largest national producer and exporter of flowers and derivatives. However, in the State of Ceará floriculture, enlarges your participation within exporter from 1990, showing increasing levels of market share in exporting trade. In this way, the question is about the behavior of the Brazilian Export segment. This article aims to analyze the general trend of comparative advantages of the States of Ceará and São Paulo in world trade of flowers between the years of 1997 to 2014. The methodology consists in calculating the Vollrath’s revealed comparative advantage index. The database was obtained through the MDIC/SECEX with information about revenue and quantities exported flowers of the two states analyzed. The results show that the Ceará increased participation in scenario exporter from 2000, obtaining the second position in total revenue of flower’s exports. These results, coupled with the higher relative presence in exporting trade, allowed the Ceará widen your competitiveness in the trading of flowers in the recent period. Keywords: agribusiness, floriculture, Vollrath’s revealed comparative advantage index.
Emprego formal na agropecuária do Estado do Paraná: Uma análise por sexo
Authors: Amaral Josineide Aquino da Silva , Teodoro Rodrigues Karla Cristina Tyskowski , Staduto Jefferson Andronio Ramundo 
Published: January 2020

O presente trabalho analisa a rotatividade e o crescimento do emprego formal na agropecuária e sua distribuição para as microrregiões do Paraná no período de 2008 a 2016. Em termos metodológicos foram utilizados dados extraídos da Relação Anual de Informações Sociais (RAIS) do Ministério do Trabalho e do Emprego (MTE). Os resultados mostraram que a rotatividade masculina e feminina é alta em todas as microrregiões do Paraná e que o emprego formal na agropecuária vem caindo ao longo do período. Em relação a criação líquida de emprego masculino mostrou que no setor agropecuário apenas 8 microrregiões do estado do Paraná tiveram crescimento do emprego acima de 3%. No caso feminino no período de 2008 a 2016 as microrregiões que tiveram maior crescimento do emprego feminino estão localizadas no Centro-Sul, Oeste, Sudeste, Noroeste Paranaense. Desta forma procede a preocupação sobre a permanecia dos trabalhadores rurais no campo.ABSTRACTThe present study analyzes the turnover and growth of formal employment in agriculture and its distribution to the microregions of Paraná from 2008 to 2016. Methodologically, data extracted from the Annual Social Information Index (RAIS) of the Ministry of Labor and of Employment (MTE). The results showed that male and female turnover is high in all microregions of Paraná and that formal employment in agriculture is falling throughout the period. In relation to the net job creation, men showed that in the agricultural sector only 8 microregions of the state of Paraná had employment growth above 3%. In the case of women, in the period 2008 to 2016, the microregions that had the greatest growth in female employment occurred in the Paraná’ Center-South, West, Southeast, Northwestern. Thus, there is concern about the permanence of rural workers in the countryside. KEYWORDS: Rotativity; Agriculture; Employment and Gender.
Estrategias para la enseñanza del pensamiento computacional y uso efectivo de tecnologías en educación infantil: una propuesta inclusiva
Authors: González González Carina Soledad 
Published: January 2020

En los últimos años, ha habido un impulso para introducir la enseñanza de la programación y el pensamiento computacional en la educación, y la robótica es una excelente herramienta para lograr esto. Sin embargo, la integración de estas habilidades fundamentales en los planes de estudio formales y oficiales sigue siendo un desafío y los educadores necesitan perspectivas pedagógicas para integrar adecuadamente los conceptos de robótica, programación y pensamiento computacional en sus aulas. Por lo tanto, en éste artículo se presenta una propuesta metodológica basada en los principios del marco de Desarrollo Tecnológico Positivo (PTD), el movimiento Maker, el constructivismo, la educación inclusiva y el aprendizaje a través de juegos, especialmente diseñado para la educación infantil. Esta propuesta ha sido validada en diferentes contextos mostrando la efectividad de la misma.
In recent years, there has been an impulse to introduce the teaching of programming and computational thinking in education, and robotics is an excellent tool to achieve this. However, the integration of these fundamental skills into formal and official curricula remains a challenge and educators need pedagogical perspectives to properly integrate the concepts of robotics, programming and computational thinking in their classrooms. Therefore, this article presents a methodological proposal based on the principles of the framework of Positive Technological Development (PTD), the Maker movement, constructivism, inclusive education and playful learning, specially designed for early childhood education. This proposal has been validated in different contexts showing its effectiveness.
The Emergence of Gerakan Arah Baru Indonesia (Garbi) and Factionalism in Partai Keadilan Sejahtera (PKS)
Authors: Priohutomo Hardianto Widyo , Kamarudin Kamarudin , Hidayat Syahrul 
Published: January 2020

This article discusses factionalism in Islamic political parties in contemporary Indonesian politics, especially within Partai Keadilan Sejahtera (Prosperous Justice Party). The factionalism inside the party has occurred since the 2004 elections due to differences in the party management between those who prefer an idealist approach and pragmatism. However, the differences between the proponents of each approach do not produce any friction leading to the emergence of a splinter group until the current leadership. It is only after the commencement of the 2015–2020 PKS leadership has the factionalism finally given birth to a new organization, Garbi (Gerakan Arah Baru Indonesia or Indonesian New Direction Movement). This study will discuss the emergence of splinter groups in PKS by using Boucek’s factionalism theory. The case of Garbi shows that stages of factionalism in PKS tend to be cooperative and leading to competition. However, before the rise of Garbi itself, which is declared as a movement instead of a political party, the factionalism within PKS has yet entered the competitive stage. This study argues that the factionalism has been heavily influenced by deep-rooted doctrinal values among its cadres that may hinder any severe impacts of competitive or even degenerative factionalism. Therefore, even though the factionalism appears to move towards degeneration in the near future, PKS appears to have managed the impact of the process with relative smooth and is able to maintain its solidity at certain level.
Rational Design and Synthesis of Highly Luminescent Multinary Cu‐In‐Zn‐S Semiconductor Nanocrystals with Tailored Nanostructures
Authors: Liu Zhenyang , Guan Zhongyuan , Li Xu , Tang Aiwei , Teng Feng 
Published: January 2020

AbstractMultinary copper chalcogenide semiconductor nanocrystals (NCs) have achieved increased attention due to their lessened toxicity and compositional versatility as well as their outstanding optical properties and optoelectronic applications in light‐emitting diodes (LEDs) and solar cells. Herein, the synthesis of highly luminescent multinary Cu‐In‐Zn‐S semiconductor NCs with tailored nanostructures, which exhibit the best absolute photoluminescence quantum yield of 90%, is presented. The tailored nanostructures are realized through the variation of the dosage and injection speed of Zn precursors, which determine the balance between Zn2+ cation diffusion and ZnS shelling reaction. The depth profile measured using X‐ray photoelectron spectroscopy reveals the gradient distribution of Zn elements from core to surface in the samples synthesized using higher feeding amounts of Zn precursors in a one‐pot method, which favors the formation of a soft core/shell structure. Time‐resolved spectroscopic studies confirm that the inward diffusion of Zn2+ and overcoating of a ZnS shell could reduce the number of intrinsic internal or surface defects, finally inducing a near‐unity radiative decay of excitons in single recombination pathway. As a demonstration, the highly luminescent multinary Cu‐In‐Zn‐S semiconductor NCs are incorporated into LEDs and a white light‐emitting diode is accessed through a two‐component strategy.
Prompting Splash Impact on Superamphiphobic Surfaces by Imposing a Viscous Part
Authors: Yu Fanfei , Lin Shiji , Yang Jinlong , Fan Yue , Wang Dehui , Chen Longquan , Deng Xu 
Published: January 2020

AbstractIt is widely acknowledged that splash impact can be suppressed by increasing the viscosity of the impinging drop. In this work, however, by imposing a highly viscous drop to a low‐viscosity drop, it is demonstrated that the splash of the low‐viscosity part of this Janus drop on superamphiphobic surfaces can be significantly promoted. The underlying mechanism is that the viscous stress exerted by the low‐viscosity component drives the viscous component moving in the opposite direction, enhancing the spreading of the low‐viscosity side and thereby its rim instability. The threshold velocity, above which splashing occurs, can be tuned by varying the viscosity ratio of the Janus drop. Moreover, the impact of the Janus drop can be employed to verify the mechanism of splash.
Water‐saving cultivation plus super rice hybrid genotype improves water productivity and yield
Authors: Chen Zongkui , Yang Xiaolong , Song Weizhou , Khan Aziz , Najeeb Ullah , Li Ping , Cao Cougui 
Published: January 2020

AbstractLabor shortage, low water availability, and poor land use practice cause serious threats to rice (Oryza sativa L.) production around the world. Semiarid cultivation is a classical strategy for achieving high water productivity (WP) with lower labor inputs. However, it remains largely unknown whether the application of “super” or drought‐resistant hybrid rice could achieve higher economic benefits (WP and yield) under semiarid cultivation. This study attempted to combine three irrigation management systems (semiarid rice cultivation, traditional flood irrigation, and dryland cultivation) with two cultivars (Yangliangyou 6, YLY6, a super hybrid rice genotype; Hanyou 113, HY113, a drought‐resistant rice genotype), and evaluate their effects on the water‐saving ability and yield (the economic benefits). The two genotypes showed no significant differences in grain yield under the semiarid and flood irrigation, and both had a greater WP (13.8–51.8%) under semiarid cultivation than under flood irrigation. YLY6 produced more panicles (P < .05), more spikelets per panicle (P < .05), and higher grain yield (P < .01) than HY113. Semiarid cultivation plus YLY6 showed higher stomatal conductance and net photosynthetic rate (P < .05), resulting in higher biomass accumulation, grain yield, and WP compared with those under other treatments. YLY6 under semiarid cultivation had greater stem water content and leaf water potential, and thus showed improvement of leaf gas exchange characteristics. In conclusion, super hybrid rice has the potential to achieve greater WP and higher grain yield under semiarid irrigation, and this combination may be introduced for sustainable rice production.
Pomalidomide, cyclophosphamide, and dexamethasone for elderly patients with relapsed and refractory multiple myeloma: A study of the Korean Multiple Myeloma Working Party (KMMWP‐164 study)
Authors: Lee Ho Sup , Kim Kihyun , Kim Seok Jin , Lee Je‐Jung , Kim Inho , Kim Jin Seok , Eom Hyeon‐Seok , Yoon Dok Hyun , Suh Cheolwon , Shin Ho‐Jin , Mun Yeung‐Chul , Kim Min Kyoung , Lim Sung‐Nam , Choi Chul Won , Kang Hye Jin , Yoon Sung‐Soo , Min Chang‐Ki ,   the Korean Multiple Myeloma Working Party (KMMWP)
Published: January 2020

AbstractPatients with transplant‐ineligible relapsed and refractory multiple myeloma (RRMM) have a short life expectancy, especially when they have failed both the proteasome inhibitor and immunomodulator therapies. This study aimed to assess the efficacy and safety of pomalidomide, cyclophosphamide, and dexamethasone (PCd) in elderly patients with RRMM. This phase 2 clinical trial recruited 55 elderly patients with RRMM. The patients underwent a 28‐day treatment cycle: pomalidomide (4 mg/day on days 1‐21, administered orally) and cyclophosphamide (400 mg/day on days 1, 8, and 15; administered orally) plus dexamethasone. The median (range) age of the patients was 73.3 (64‐86) years, and 8 (14.5%) patients who were ≥ 80 years old. Eight (14.5%) and 31 (56.4%) patients exhibited stage III (revised international staging system) and frail status (simplified frailty scale), respectively. The overall response rate (ORR) and clinical benefit rate (CBR) of PCd therapy were 58.2% and 72.7%, respectively. The median PFS and median overall survival (OS) were 6.90 months (95% CI, 4.7‐9.0) and 18.48 months (95% CI, 9.4‐27.6), respectively. The incidence rate of grade ≥ 3 non‐hematological toxicities was 70.8%. In particular, the incidence rate of primary infection was 45.4%, including 21.8% for pneumonia, 9.0% for sepsis, and 14.6% for febrile neutropenia. In conclusion, PCd is an effective regimen for elderly patients with RRMM who had failed both bortezomib and lenalidomide treatments, but in whom the treatment‐associated infection is the main cause of morbidity and mortality.
The impact of Lactococcus lactis (probiotic nasal rinse) co‐culture on growth of patient‐derived strains of Pseudomonas aeruginosa
Authors: Cho Do‐Yeon , Skinner Daniel , Lim Dong Jin , Mclemore John G. , Koch Connor G , Zhang Shaoyan , Swords William E. , Hunter Ryan , Crossman David K , Crowley Michael R. , Grayson Jessica W. , Rowe Steven M. , Woodworth Bradford A. 
Published: January 2020

BackgroundThe Lactococcus strain of bacteria has been introduced as a probiotic nasal rinse for alleged salubrious effects on the sinonasal bacterial microbiome. However, data regarding interactions with pathogenic bacteria within the sinuses are lacking. The purpose of this study is to assess the interaction between L. lactis and patient‐derived Pseudomonas aeruginosa, an opportunistic pathogen in recalcitrant chronic rhinosinusitis (CRS).MethodsCommercially available probiotic suspension containing L. lactis W136 was grown in an anaerobic chamber and colonies were isolated. Colonies were co‐cultured with patient‐derived P. aeruginosa strains in the presence of porcine gastric mucin (mimicking human mucus) for 72 hours. P. aeruginosa cultures without L. lactis served as controls. Colony forming units (CFUs) were compared.ResultsSix P. aeruginosa isolates collected from 5 CRS patients (3 isolates from cystic fibrosis [CF], 1 mucoid strain) and laboratory strain PAO1 were co‐cultured with L. lactis. There was no statistical difference in CFUs of 5 P. aeruginosa isolates grown with L. lactis compared to CFUs without presence of L. lactis. CFU counts were much higher when the mucoid strain was co‐cultured with L. lactis (CFU+L.lactis = 1.9 × 108 ± 1.44 × 107, CFU–L.lactis = 1.3 × 108 ± 8.9 × 106, p = 0.01, n = 7). L. lactis suppressed the growth of 1 P. aeruginosa strain (CFU+L.lactis = 2.15 × 108 ± 2.9 × 107, CFU–L.lactis = 3.95 × 108 ± 4.8 × 106, p = 0.03, n = 7).ConclusionL. lactis suppressed the growth of 1 patient P. aeruginosa isolate and induced growth of another (a mucoid strain) in in vitro co‐culture setting in the presence of mucin. Further experiments are required to assess the underlying interactions between L. lactis and P. aeruginosa.
New biocomposite obtained using poly(3‐hydroxybutyrate‐co‐3‐hydroxyhexanoate) (PHBH) and microfibrillated cellulose
Authors: Giubilini Alberto , Sciancalepore Corrado , Messori Massimo , Bondioli Federica 
Published: January 2020

ABSTRACTThis research evaluates the effects of filler content and silanization on thermal, morphological and mechanical properties of poly(3‐hydroxybutyrate‐co‐3‐hydroxyhexanoate) (PHBH)‐based composites. Microfibrillated cellulose (MFC) was obtained by a mechanical treatment of high‐pressure homogenization, starting from oat hull fiber, a byproduct of the agri‐food sector. MFC reinforced PHBH composites were prepared by melt compounding. SEM and FT‐IR analysis showed a good dispersion of the filler in the polymeric matrix, denoting the effectiveness of the surface silanization process. The thermal stability of PHBH composites remains substantially unchanged, and the glass transition temperature marginally increases with the increase of the filler content. Furthermore, silanized MFC shows slightly reinforcing mechanical effects on PHBH composites, such as the increase of 10% of the Young modulus with an increase of the maximum tensile stress as well. This finding has an economical interest since the results showed that MFC, deriving from a byproduct, can be successfully used as filler, decreasing the cost of the bio‐based compound leaving substantially unaltered its mechanical and thermal properties. © 2020 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48953.
rac‐ and meso‐Cyclohexanoids: Their α‐, β‐glycosidases, antibacterial, antifungal activities, and molecular docking studies
Authors: Karakılıç Emel , Baran Şule , Öğütçü Hatice , Akdemir Atilla , Baran Arif 
Published: January 2020

AbstractAn efficient and versatile synthesis method has been postulated for hydroxymethylated rac‐ and meso‐cyclohexanoid derivatives. The synthesis of these stereoisomers was achieved easily with traditional methods using hexahydroisobenzofuran 6, prepared from commercially available cis‐hydrophthalic anhydride. The study, involving diastereoselective epoxidation and cis‐hydroxylation, was conducted to obtain epoxy‐, cis‐, and trans‐diol‐furans 7, 8, and 9. After sulfamic acid‐catalyzed ring‐opening reaction of the epoxide and furan rings, rac‐ and meso‐tetraacetates 14, 15, and 16 were afforded. Hydrolysis of acetate groups with ammonia in absolute methanol yielded the desired tetrols rac‐17, meso‐18, and meso‐19. All structures, after purification by chromatographic methods and elucidation by spectral techniques, were screened against α‐ and β‐glucosidases. Compounds 7, 8, 10, 17, 18, and 19 were also evaluated for their antibacterial and antifungal activity against some selected synthesized compounds with varying degrees of inhibitory effects on the growth of different pathogenic microorganisms by the well‐diffusion method. In addition, Saccharomyces cerevisiae α‐glucosidase molecular modeling studies were performed for all rac‐ and meso‐compounds 7, 8, 10, 17, 18, and 19.
Next‐generation polymerized human hemoglobins in hepatic bioreactor simulations
Authors: Cuddington Clayton , Moses Savannah , Belcher Donald , Ramesh Niral , Palmer Andre 
Published: January 2020

AbstractHepatic hollow fiber (HF) bioreactors can be used to provide temporary support to patients experiencing liver failure. Before being connected to the patient's circulation, cells in the bioreactor must be exposed to a range of physiological O2 concentrations as observed in the liver sinusoid to ensure proper performance. This zonation in cellular oxygenation promotes differences in hepatocyte phenotype and may better approximate the performance of a real liver within the bioreactor. Polymerized human hemoglobin (PolyhHb) locked in the tense quaternary state (T‐state) has the potential to both supply and regulate O2 transport to cultured hepatocytes in the bioreactor due to its low O2 affinity. In this study, T‐state PolyhHb production and purification processes were optimized to minimize the concentration of low‐molecular‐weight PolyhHb species in solution. Deconvolution of size‐exclusion chromatography spectra was performed to calculate the distribution of polymeric Hb species in the final product. Fluid flow and mass transport within a single fiber of a hepatic HF bioreactor was computationally modeled with finite element methods to simulate the effects of employing T‐state PolyhHb to facilitate O2 transport in a hepatic bioreactor system. Optimal bioreactor performance was defined as having a combined hypoxic and hyperoxic volume fraction in the extracapillary space of less than 0.05 where multiple zones were observed. The Damköhler number and Sherwood number had strong inverse relationships at each cell density and fiber thickness combination. These results suggest that targeting a specific Damköhler number may be beneficial for optimal hepatic HF bioreactor operation.
Macro and Micro Algae in Pollution Control and Biofuel Production – A Review
Authors: Jalilian Neda , Najafpour Ghasem D. , Khajouei Mohammad 
Published: January 2020

AbstractMicroalgae are biological sources with an extensive range of biotechnological applications, e.g., for bioremediation of industrial and municipal wastes. Microalgae are used to monitor environmental toxicants like pesticides, heavy metals, and pharmaceuticals and in the final stage of wastewater treatment when organic pollution should be removed. CO2 capturing is also important due to the environmental issues. Macro/microalgae cultures, depending on their growth stages and life cycles, have great potential for CO2 fixation. They are a dominant group of microorganisms for biological treatments with regards to their substantial biosorption ability to deactivate toxic heavy metals. Actual carbon biofixation can be employed in the direction of environmental sustainability and economic facility. Besides, algae are sustainable feedstock to produce a wide range of biofuels by applying thermochemical or biological conversion methods.