bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adoption and Attitudes of eHealth Among People Living With HIV and Their Physicians: Online Multicenter Questionnaire Study
Authors: Jacomet Christine , Ologeanu-Taddei Roxana , Prouteau Justine , Lambert Céline , Linard Françoise , Bastiani Pascale , Dellamonica Pierre 
Published: February 2020

Background
The development of electronic health (eHealth) has offered the opportunity for remote care provision. eHealth addresses issues for patients and professionals favoring autonomy and compliance, respectively, while fostering closer links both between patients and health care professionals and among health care professionals themselves.

Objective
The aim of this study was to analyze the patterns of use, benefits, and perceived obstacles in eHealth among people living with HIV (PLHIV) and their caring physicians at hospitals.

Methods
An online multicenter observational survey was conducted October 15-19, 2018 in 51 medical units across France by means of self-administered questionnaires to collect sociodemographic and medical data, and perceptions of eHealth. Multiple correspondence analysis followed by mixed unsupervised classification were performed to analyze data of the respondents.

Results
A total of 279 PLHIV and 219 physicians responded to all parts of the questionnaire. Three groups of PLHIV were identified based on multivariate analysis. Group 1 comprised “eHealth believers” (121/279, 43.4%), who were more frequently above 60 years old and more likely to be receiving treatments other than antiretrovirals. Group 2, the “technology skeptics” (86/279, 30.8%), comprised more women with at least one child. Group 3, the “internet adopters” (72/279, 25.8%), were more frequently under 49 years of age, men who have sex with men, and more likely to use mobile apps for obtaining wellness/health information and related subjects. Three groups of physicians also emerged. Group 1 comprised those “strongly confident in eHealth” (95/219, 43.4%), who more frequently used mobile apps for wellness/health information and were more likely to accept prescription assistance software. Group 2 comprised physicians “strongly opposed to eHealth” (80/219, 36.5%), frequently asserting that eHealth challenges confidentiality. Group 3 were “open to eHealth” (44/219, 20.1%), comprising a higher proportion of infectious disease specialists, and were more likely to believe that medical apps are useful for patient education and information. No link was found between the groups of PLHIV and physicians.

Conclusions
The literature on eHealth mainly classifies people as enthusiasts and skeptics; however, we identified a third profile among both PLHIV and physicians, albeit without a direct link between them. For PLHIV, this third group is attentive to eHealth for improving their health condition, and for physicians, this group considers eHealth to offer benefits to patients and their own practice.
Neural Network–Based Clinical Prediction System for Identifying the Clinical Effects of Saffron (Crocus sativus L) Supplement Therapy on Allergic Asthma: Model Evaluation Study
Authors: Hosseini Seyed Ahmad , Jamshidnezhad Amir , Zilaee Marzie , Fouladi Dehaghi Behzad , Mohammadi Abbas , Hosseini Seyed Mohsen 
Published: February 2020

Background
Asthma is commonly associated with chronic airway inflammation and is the underlying cause of over a million deaths each year. Crocus sativus L, commonly known as saffron, when used in the form of traditional medicines, has demonstrated anti-inflammatory effects which may be beneficial to individuals with asthma.

Objective
The objective of this study was to develop a clinical prediction system using an artificial neural network to detect the effects of C sativus L supplements on patients with allergic asthma.

Methods
A genetic algorithm–modified neural network predictor system was developed to detect the level of effectiveness of C sativus L using features extracted from the clinical, immunologic, hematologic, and demographic information of patients with asthma. The study included data from men (n=40) and women (n=40) individuals with mild or moderate allergic asthma from 18 to 65 years of age. The aim of the model was to estimate and predict the level of effect of C sativus L supplements on each asthma risk factor and to predict the level of alleviation in patients with asthma. A genetic algorithm was used to extract input features for the clinical prediction system to improve its predictive performance. Moreover, an optimization model was developed for the artificial neural network component that classifies the patients with asthma using C sativus L supplement therapy.

Results
The best overall performance of the clinical prediction system was an accuracy greater than 99% for training and testing data. The genetic algorithm–modified neural network predicted the level of effect with high accuracy for anti–heat shock protein (anti-HSP), high sensitivity C-reactive protein (hs-CRP), forced expiratory volume in the first second of expiration (FEV1), forced vital capacity (FVC), the ratio of FEV1/FVC, and forced expiratory flow (FEF25%-75%) for testing data (anti-HSP: 96.5%; hs-CRP: 98.9%; FEV1: 98.1%; FVC: 97.5%; FEV1/FVC ratio: 97%; and FEF25%-75%: 96.7%, respectively).

Conclusions
The clinical prediction system developed in this study was effective in predicting the effect of C sativus L supplements on patients with allergic asthma. This clinical prediction system may help clinicians to identify early on which clinical factors in asthma will improve over the course of treatment and, in doing so, help clinicians to develop effective treatment plans for patients with asthma.
Isolation of terpenoid compound of n-hexane extract of Marsilea crenata Presl..
Authors: Ma'arif Burhan , Agil Mangestuti , Widyowati Retno 
Published: February 2020

Isolation, identification, and structure elucidation of terpenoid compounds from an n-hexane extract of Marsilea crenata Presl., had been done. The leaves of M. crenata was extracted using n-hexane solvent. The extract then separated with vacuum column chromatography and open column chromatography to obtain the isolate. Furthermore, the isolate was identified and elucidated using UV-Vis, FT-IR, 1H-NMR, 13C- NMR, and 2D-NMR (COSY, HMQC, and HMBC). The identification and elucidation of the isolated structure from an n-hexane extract of M. crenata leaves indicate the isolate was a pentacyclic triterpenoid.
Benefit administration of vitamin B1, B6, and B12 on the depression symptom in hemodialysis patients
Authors: Pinzon Rizaldy Taslim , Ardiani Birgitta Lisbethiara 
Published: February 2020

Chronic kidney disease (CKD) is a disease that causes a decrease in kidney function, which can be seen from GFR (Glomerulus Filtration Rate) value, which is less than 60 ml/minute/1.73 m2 in minimum three months. Depression is a psychological problem in a patient with chronic kidney disease undergoing hemodialysis. The previous study has shown that giving vitamin B combination can improve depression symptoms. To measure the benefit of vitamin B1, B6, B12 parenterally for depression symptoms in chronic kidney disease patients undergoing hemodialysis. This study used an experimental design (one group pre and post-test) in 117 patient that obtained using a consecutive sampling method. Depression score was measured by the HADS questionnaire before given vitamin B (pre-test) and after given vitamin B (post-test). Data were statistically analyzed using a licensed SPSS program with paired t-test/Non-Parametric Wilcoxon. The relationship between the history of the use of the antihypertensive, antidiabetic, folic acid drug, and depression scores were not showing significant results (p > 0.05). The relationship between administration of vitamins B1, B6, and B12 and the patient's depression score showed a decrease but not significant (p = 0.522). There was no significant difference after the administration of vitamin B1, B6, and B12 on the depression score of patients with chronic kidney disease undergoing hemodialysis at Bethesda and Panti Rapih Hospital in Yogyakarta.
Apresentação: Pesquisar é estranhar a realidade
Authors: Simonini Eduardo , Romagnoli Roberta Carvalho 
Published: February 2020

A produção de conhecimento não é uma linha reta que segue em direção a um inconteste progresso. Ao contrário disso, tal produção sofre contínuas perturbações, no entrelaçamento de saberes, práticas, maneiras de pensar. Certo é que tais questões trouxeram interferência na própria noção de pesquisa científica, sendo que a realidade, vista como sendo um quebra-cabeça a ser decifrado – um código a ser desvendado por meio de ferramentas teórico-metodológicas cada vez mais apuradas – foi assumida como possuindo uma essência imutável a servir de modelo a partir da qual se organizavam todas as variações possíveis. Compreender esse núcleo fundante, essa verdade, ponto da gênese do cosmos, das grandes narrativas e de tudo que o difere, se tornou um projeto, seguramente ambicioso, da ciência moderna em seus desdobramentos em diferentes áreas de conhecimento. Porém, seria possível fazer da dúvida metódica cartesiana um instrumento de questionamento das verdades que a própria modernidade acolheu para si: verdades instaladas em grandes narrativas a definir posições de gênero, de universo, de educação, de conduta, de futuro, de ordem, de felicidade, de humanidade? Seria possível estranhar inclusive a própria noção de “essência”, de “verdade” e de “realidade”? Seria possível novamente utilizar a ferramenta da dúvida para produzir estranhamento no que já está estabelecido como inconteste e colocar movimento problematizador naquilo assumido como inquestionável? A partir desses desassossegos, os artigos reunidos neste dossiê têm por proposta – cada um em seu campo de problematização – trazer um pensar que estranhe, colocando movimento em perspectivas consideradas estáveis em sua naturalidade, driblando a “verdade” e acolhendo as interferências produzidas (tanto na realidade, quanto no próprio pesquisador) pelo processo de conhecer.
“Garrapata Hércules”, Eragrostis superba (Peyr), variedad de pasto para zonas áridas y semiáridas
Authors: Beltrán López Sergio , García Díaz Carlos Alberto , Loredo Osti Catarina , Urrutia Morales Jorge , Hernández Alatorre José Antonio , Gámez Vázquez Héctor Guillermo 
Published: February 2020

El pasto Garrapata (Eragrostis superba) es una gramínea perenne, de buen valor forrajero, originaria de Sudáfrica, se adapta bien a una amplia gama de suelos y condiciones climáticas.La variedad Hércules proviene de colectas realizadas en el centro y norte de México. Fue evaluada en zonas áridas y semiáridas, en temporal y riego desde 1986 hasta la obtención del registro en el año 2008. El registro otorgado por el Servicio Nacional de Inspección y Certificación de Semillas (SNICS) es: ERA-002-060608. A la fecha, la primera variedad registrada para esta especie en México. El rendimiento medio anual por hectárea de esta variedad oscila entre 886 y 1,947 kg de materia seca (MS) en condiciones de temporal, con una media de 1,200 kg MS ha-1 y entre 24.8 y 11.4 t MS ha-1 en condiciones de riego con una media de 18.1 t MS ha-1. Esta variedad de pasto es tolerante a la sequía, de fácil establecimiento y de rápido crecimiento, apetecible para el ganado, resistente al pastoreo y tolerante a la salinidad. Es una especie utilizada para la rehabilitación de agostaderos degradados y conservación de suelo en pastizales de zonas áridas y semiáridas en México.
Conocimientos y prácticas de profesionales de la salud en uso de medicamentos
Authors: Rojas Marín Maria Zoraida 
Published: February 2020

Identificar conocimientos y prácticas del personal de salud respecto al uso de medicamentos en vías y condiciones diferentes a las establecidas en la ficha técnica. Método: Estudio cuantitativo de tipo descriptivo y corte transversal en dos fases: la primera consistió en una revisión de la literatura en donde se incluyeron de forma inicial 82 artículos, de los cuales ocho fueron elegidos para la revisión; la segunda fase estuvo conformada por 31 participantes que trabajaban en Instituciones de Salud; fueron seleccionados de forma no probabilista secuencial, a quienes se les aplicó un cuestionario, para identificar conocimientos y prácticas desarrolladas, el cual fue evaluado por 3 profesores expertos en la temática; también se realizó una prueba piloto. Resultados: La revisión de la literatura fue referente para la construcción del instrumento. En la segunda fase el 87% de los participantes no conocían el concepto off label, el 65% fueron profesionales de la enfermería que describieron su experiencia como una práctica que no se podría considerar como off label por la falta de soporte científico. Los medicamentos antiinfecciosos, antifúngicos, analgésicos y electrolitos, fueron los grupos de mayor utilización. La principal modificación fue en el cambio de la vía de administración, seguido de la indicación y el 71% de las prácticas no fue descrita en los registros clínicos. Conclusiones: Existe limitada evidencia que soporte el uso de medicamentos en vías y condiciones no establecidos en la ficha técnica; no existe una definición clara y común, presentándose un desconocimiento en los profesionales de la salud.
How Audit Committee Chairs Address Information-Processing Barriers
Authors: Free Clinton , Trotman Andrew J. , Trotman Ken T. 
Published: February 2020

ABTRACT
This study investigates the way that experienced audit committee Chairs address barriers to effective performance. We conceptualize audit committees as groups of individuals gathering, elaborating, and sharing information, and identify key group barriers to effective audit committee oversight. Drawing on 24 interviews with audit committee Chairs from leading Australian-listed companies, we provide new evidence of the approaches used in practice to address information-processing barriers faced by audit committees. Specifically, we identify six key mechanisms: (1) audit committee composition; (2) pre-meetings; (3) handling of disagreements between management and auditors; (4) formal audit committee meeting facilitation; (5) promoting audit committee skepticism; and (6) external auditor selection. Our findings provide insights for audit committee members, audit partners, and policy-makers as they aim to improve financial reporting and audit quality. These findings also have important implications for research designs of future experimental research.
Right ventricular function assessed by cardiac magnetic resonance predicts the response to resynchronization therapy
Authors: Manca Paolo , Cossa Stefano , Matta Gildo , Scalone Antonio , Tola Gianfranco , Schintu Barbara , Setzu Agostino , Melis Marco , Giardina Achille , Corda Marco , Sinagra Gianfranco , Porcu Maurizio 
Published: February 2020

Background and aim
Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in chronic heart failure symptomatic patients with broad QRS who are already undergoing optimal medical treatment. However, approximately one-third of implanted patients do not show any benefit from this treatment. Right ventricle (RV) dysfunction leads to a worse outcome in patients with heart failure, but its role in predicting the response to CRT has shown conflicting results. The purpose of our study was to investigate how the RV function, assessed by cardiac magnetic resonance (CMR), could influence the outcome of heart failure patients treated with CRT.

Methods and results
We retrospectively enrolled 72 heart failure patients, 38 affected by dilated cardiomyopathy (DCM) and 34 by ischemic dysfunction, with left bundle branch block, QRS greater than 120 ms and standard indications to CRT. We defined the response to CRT as an improvement of at least 10% of the left ventricular ejection fraction (LVEF) or at least one of the NYHA functional classes. We stratified the population into two groups based on the right ventricle ejection fraction (RVEF) at CMR: group 1 RVEF at least 55% (n = 32), group 2 RVEF less than 55% (n = 40). After a mean follow-up of 38 ± 12 months, 44 patients (61%) were considered responders whereas 28 (39%) did not show any benefit. Patients in group 1 had a higher rate of response to CRT (75 vs. 50%, P = 0.03). At the univariate analysis RVEF [54 vs. 43%; confidence interval (CI) = 0.907–0.980; hazard ratio = 0.943; P = 0.003], RV end-systolic volume (56 vs. 84 ml; CI = 1.005–1.034; hazard ratio = 1.019; P = 0.008) and tricuspid annular plane systolic excursion (TAPSE) (16.4 vs. 14 mm; CI 0.745–0.976; heart rate = 0.853; P = 0.021) were the parameters most strongly associated with the response to CRT. Male sex, atrial fibrillation, and older age also negatively influenced the outcome. At a multivariate model, RVEF and older age remained significant.

Conclusion
In our experience, patients with RV dysfunction less likely benefited from CRT. RV assessment, studied with CMR, appears to be a good predictor of the response to biventricular stimulation.
Implikasi Erupsi Gunung Agung Terhadap Kegiatan Pariwisata Di Kawasan Pura Besakih
Authors: Aristiani Ni Kadek Pande , Pujani Luh Putu Kerti 
Published: February 2020

Besakih Temple is the bigest temple in Bali located on the slopes of Mount Agung exactly in Besakih village, Rendang district, Karangasem regency. In addition to being a center of religious ceremonies at Besakih Temple there are also tourism activities. Mount Agung is the highest mountain in Bali and has several times the last eruption occurred in 2017. The researchs try to find the condition of tourism before and after the eruption of Mount Agung in the area of Besakih Temple.
The research method used is qulalitative research with comparative data analysis techniques to analyze the condition of tourism before the eruption of Mount Agung and the implications of eruption Mount Agung for tourism activities in the area of Besakih Temple. The data sources, from primary data and secondary data. The concept used are concept of eruption, concept of cultural attraction, concept of the Besakih Temple as spiritual phenomenon, concept of operational, concept of the informal sector in tourism.
The result of the research shows that the influence of Mount Agung eruption on tourism activity in area of Besakih Temple is viewed based on the level of tourist visit, the condition of tourist attraction, the comfort of the area, the cleanliness of the area, the operational and income of the local tour guide, the motorcycle drivers, artshop, kiosks, activity of informal tourism sector in the area of Besakih Temple. The area of Besakih Temple managers should synergize with the government and community to conduct recovery of tourism activities in the area of Besakih Temple.
Keywords: Implication, Eruption, Tourism Activity, Pura Besakih
Implikasi Erupsi Gunung Agung Terhadap Atraksi Wisata Air Di Daya Tarik Wisata Pantai Melasti, Desa Serangan, Kecamatan Denpasar Selatan, Kota Denpasar Bali
Authors: Novenia Melinda , Pujani Luh Putu Kerti 
Published: February 2020

Tourism attraction by watersport on Melasti Beach Serangan from the beginning of December 2017 until mid- December 2017 the number of tourist visits has decreased to reach its lowest point of zero percent, and as for some of the tourist services business attractions are laid off in a certain period due to the eruption of Mount Agung. This research related to the implications of the eruption of Mount Agung on Melasti Serangan Beach is to find out how much the impact of the Mount Agung eruption on tourism on Serangan Island was located quite far from Mount Agung
Consept that used to discuss the problems in this study is the concept of implication and concept of watersports. The method use qualitative data analysis techniques by conducting observations, in-depth interviews, and documentation. The technique of determining the informant is done by purposive sampling. Source of data obtained primary data sources in the form of in-depth interviews to the management of watersport tourism attractions in Melasti Serangan Beach and direct observation in the field. The secondary data source of this study is in the form of the Denpasar City tourism service website, such as the number of tourist visits to Serangan Island and previous research journals related to this study.
The implication of the eruption of Mount Agung on watersport tourism attractions in Melasti Serangan Beach includes a direct influence which has resulted in a decrease in tourist visits. The influence referred includes changes in operational hours, but without shortening working hours. Almost all employees experience a policy of laying off a maximum of 20 days. A decrease in the number of tourist visits, especially in December. Similarly, the amount of income earned only reaches less than 50% of normal days.

Keywords : implication, eruption, management, watersport
Strategi Pengembangan Potensi Wisata Bahari Pulau Tunda, Kecamatan Tirtayasa, Kabupaten Serang, Provinsi Banten
Authors: Prameswara Bangga , Suryawan Ida Bagus 
Published: February 2020

The study aims to determine Development Strategy the potency of the Tunda Island as a tourist attraction in the Serang Regency, Banten Province. How the development of appropriate strategy to overcome obstacles in the development of Tunda Island Coast region as a Marine Tourism attraction in Serang Regency, Banten Province.
This study was conducted to determine the Tunda Island as a marine tourism destination Serang Regency were reviewed by using SWOT analysis. This study uses quialitative research methods with data collection techniques such as interviews, observation, and documentation studies.
The results of the research carried out that Pulau Tunda as a marine tourism attraction in Serang Regency has the power in the form of underwater natural potential that is different from other islands in Serang Regency, besides Tunda Island has a considerable opportunity for increasing tourism needs and locations that tend to strategic. However, Pulau Tunda has weaknesses in the quality of human resources as well as low tourism support facilities and garbage that has not been managed properly. Meanwhile the threat faced by Tunda Island is currently the operation of sand miners and the lack of attention from the local government.

Keywords: Development Strategy, Tunda Island, Marine Tourism
Dampak Pendidikan Kewirausahaan pada Entrepreneur Behavior Index (EBI) dan Intensi Berwirausaha Mahasiswa Fakultas Ekonomi dan Bisnis Universitas Udayana di Denpasar
Authors: Suasana I Gst. A. Kt. Gd. , Ekawati Ni Wayan , Sudiana I Ketut , Wardana I Gede 
Published: February 2020

Tujuan penelitian adalah menjelaskan dampak pendidikan kewirausahaan terhadap niat berwirausaha, menjelaskan dampak pendidikan kewirausahaan terhadap EBI, menjelaskan dampak EBI terhadap niat berwirausaha dan menjelaskan peran EBI sebagai mediator dampak antara pendidikan kewirausahaan dan niat berwirausaha. Penelitian dilakukan terhadap pada mahasiswa program S1 Reguler FEB-Unud yang telah lulus mata kuliah kewirausahaan dalam kurun waktu tiga semester terakhir. Penelitian menggunakan sampel individu sebagai unit analisis dengan ukuran sampel responden 200 orang dan dibagi ke dalam tiga prodi secara proposional. Teknik analisis menggunakan analisis SEM berbasis AMOS. Hasil analisis menemukan bahwa pendidikan kewirausahaan berdampak signifikan terhadap niat berwirausaha, pendidikan kewirausahaan berdampak signifikan terhadap EBI, EBI berdampak signifikan terhadap niat berwirausaha, dan EBI berperan signifikan memediasi secara parsial dampak pendidikan kewirausahaan terhadap niat berwirausaha. Artinya bahwa, menumbuhkan dan mengembangkan niat berwirausaha lulusan perguruan tinggi, dapat dilakukan melalui pengembangan kurikulum pendidikan kewirausahaan, namun pendidikan tersebut tidak sepenuhnya harus dibebani dengan peningkatan nilai-nilai karakter individu (EBI).
Kata Kunci: pendidikan kewirausahaan, entrepreneur behavior index (EBI), dan intensi/niat berwirausaha.