bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANCA-associated vasculitis in a 14 years-old patient: a clinical case
Authors: Burlutskaya A. V. , Savelyeva N. V. , Тaran N. S. 
Published: October 2020

Background. ANCA-associated systemic vasculitis is a rare childhood disease. Antineutrophil cytoplasmic autoantibodies (ANCA)-related vasculitises include microscopic polyangiitis, granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis. Their rarity often leads to a late diagnosis, rapid disability and high mortality in patients due to aggressive respiratory, pulmonary lesion and renal failure.Clinical Case Description. The patient suffered from a recurrent bronchoobstructive syndrome with signs of respiratory failure, obscure origin fever and chronic rhinitis with nasal bleeding for 6 months. The patient was diagnosed with obstructive bronchitis (putative bronchial asthma debut), received antibacterial therapy and inhalation bronchodilators without stable improvement during the entire period. Skin haemorrhages and arthralgia stimulated diagnostic research to establish ANCA-associated systemic vasculitis (presence of proteinase 3-specifi c ANCAs in titre 1/80). CT lung scanning revealed frosted glass foci of reduced pulmonary pneumatisation and signs of bilateral bronchoobstruction. Immunosuppressive therapy with glucocorticosteroids (methylprednisolone pulse therapy No. 3, 1000 mg intravenously on alternate days, subsequent per os administration of 1 mg/kg/day) and cyclophosphamide (500 mg intravenously once per 28 days) was prescribed. This led to the positive dynamics with eliminated fever and skin haemorrhages, as well as essentially reduced signs of respiratory failure.Conclusion. Diagnosis of systemic vasculitis is often complicated and long-term due to commonly non-specifi c debut symptoms of autoimmune disorders. In the described case, the fi rst 6 months of illness displayed intoxication and bronchoobstruction with signs of respiratory failure. Haemorrhagic rashes, arthralgias and the presence of ANCAs are proxy to vasculitis. Standard immunosuppressive therapy for ANCA-associated vasculitis improved the patient’s condition.
Clinical and pharmacological risk assessment for thrombohaemorrhagic complications after total lower limb arthroplasty
Authors: Golovko L. S. , Safronenko A. V. , Sukhorukova N. V. , Gantsgorn E. V. 
Published: October 2020

Background. Anticoagulant and haemostatic drugs are used to prevent thrombosis and bleeding after arthroplasty. Combined therapy with these divergent agents, especially in comorbid patients, is not regulated in relevant clinical guidelines and may lead to a reduced effi cacy.Objectives. Assessment of the effect of time interval (TI) in variant combined settings of haemostatic and anticoagulant drugs and concomitant pathology on the development of thrombohaemorrhagic complications after hip or knee arthroplasty.Мethods. In a retrospective study, we analysed patients’ somatic status, haemostatic and anticoagulant drug regimes and their combined impact on the development of thrombohaemorrhagic complications in early postoperative period.Results. We analysed 253 case histories with total replacement of main lower limb joints. Two cohorts were defi ned with respect to TI between haemostatic and anticoagulant drug applications. TI was 17 h or less (n = 145; 57.31%) in cohort 1 and 18–24 h (n = 108; 42.68%) — in cohort 2. A total of 29 drug combinations were tested. Thrombohaemorrhagic complications were observed in 27 (10.67%) patients, with 22 (81.48%) in cohort 1. Thromboses in regimes with tranexamic acid developed in cohort 1 (p = 0.038) at a 2.2-folds higher rate than in cohort 2 (p < 0.05). Thrombosis development was infl uenced by grade 2 obesity (relative risk = 8.75, p = 0.037), type 2 diabetes (relative risk = 21, p = 0.00001), myocardial infarction (relative risk = 16.875, p = 0.00002), venous pathology (relative risk = 8.1, p = 0.045) and the patient’s age over 75 (relative risk = 6.8, p = 0.029). Age over 75 years increased the risk of bleeding by a factor of 12 (relative risk = 12, p = 0.015).Conclusion. After main joint arthroplasty, differential measures to prevent thrombohaemorrhagic complications include a minimal 18-h TI between haemostatic and anticoagulant agent applications, especially in tranexamic acid regimes, and the consideration of concomitant risk factors, such as grade 2 obesity, type 2 diabetes, myocardial infarction in history, venous pathology and age over 75 years.
Endoscopic-assisted paramedian infratentorial supracerebellar approach for pineal cyst – How I do it Video clip
Authors: Tanaka Riki , Takeuchi Kazuhito , Ansari Ahmed , Sasaki Kento , Miyatani Kyosuke , Yamada Yasuhiro , Kawase Tsukasa , Kato Yoko , Horiguchi Akihiko 
Published: October 2020

Background:
The endoscopic supracerebellar-infratentorial (SCIT) approach is a viable method to access pathology of the posterior incisura, but a narrow working space and frequent instrument conflict can potentially limit its surgical efficacy. We planned an endoscopic-assisted paramedian infratentorial supracerebellar approach for pineal cyst.

Case Description:
Patient was placed in prone position under general anesthesia. His head was rotated to the left side slightly. The location of the transverse sinus was detected with navigation system. A 5 cm linear skin incision was performed, and a 2 cm craniectomy was performed about 2 cm left of the median. The transverse sinus was little bit exposed. Dura was incised in a U-shaped incision with the transverse sinus at the base. The endoscope was advanced along with the culmen. At that time, we observed inferior and superior vermian vein. After reaching to the thick arachnoid near by galenic system, the arachnoid membrane was incised and the CSF was evacuated. After that, the cerebellum became soft and the surgical corridor became large. The arachnoid membrane was incised widely. Pineal cyst, precentral cerebellar vein, bilateral internal occipital vein and great vein of galen were exposed. There were some small veins on the pineal cyst, but the adhesion was not so severe. The cyst was dissected from these small veins. There was no adhesion between the cyst and surrounding brain except for the pineal recess. Bilateral ICV was seen behind the cyst. There was feeding artery and draining vein on the antero-lateral part of the cyst. These vessels were coagulated and cut, then the cyst was removed. After the removal, we confirmed complete removal of the cyst and hemostasis.

Conclusion:
Endoscopic-assisted paramedian SCIT approach for pineal cyst in prone position is a reasonable and efficient access for posterior third ventricular lesions. The learning curve, maneuverability in small space, and instrument conflict limit efficacy.
Surgical clip occlusion of the V3 segment to prevent recurrent cerebral infarction associated with extracranial vertebral artery dissection: A case report
Authors: Aiura Ryo , Matsumoto Masaki , Mizutani Tohru , Sugiyama Tatsuya , Tanioka Daisuke 
Published: October 2020

Background:
Recurrent cerebral infarction caused by traumatic extracranial vertebral artery dissection (EVAD) is treated medically and surgically. We report a case of EVAD that was treated using surgical clip occlusion of the V3 segment to prevent recurrent cerebral infarction.

Case Description:
A 48-year-old man was admitted for a cerebral infarction caused by EVAD and was treated using 200 mg/day cilostazol. Afterward, the cerebral infarction recurred. Digital subtraction angiography revealed that initial severe stenosis of the VA ostium resulted in the final occlusion and that collateral vessels to the VA remained. We continued antiplatelet therapy, but the cerebral infarction recurred due to thromboembolism of the collateral vessels. Parent artery occlusion was planned. We exposed the V3 segment of the VA and clipped it to prevent the recurrence of cerebral infarction.

Conclusion:
Surgical clip occlusion of the V3 segment was effective for treating recurrent cerebral infarction caused by traumatic EVAD that had remained an issue despite continuing medical therapy.
Primary Ewing’s sarcoma of the C2 vertebra with progressive quadriparesis: Report of a rare case and review of the literature
Authors: Khatavi Anandkumar , Dhillon Charanjit Singh , Chhasatia Nilay , Pophale Chetan , Nanakkal Shafeek , Varshney Amit 
Published: October 2020

Background:
Ewing’s sarcoma is a malignant primitive neuroectodermal tumor (PNET) of childhood and adolescence. Primary Ewing’s sarcoma of the spine is uncommon, and even more rarely involves the C2 vertebra.

Case Description:
A 14-year-old patient was admitted with a history of chronic neck pain, which exacerbated after playing contact sports 3 weeks before presentation. On initial examination, he had pain radiating into the left upper extremity plus spasticity in all the four limbs. The cervical X-rays revealed a mixed sclerotic-lytic lesion involving the C2 vertebral body. The CT bony and soft-tissue windows documented predominant left-sided tumor invasion of the posterior elements, pedicles, and body of C2 along with extension into the spinal canal resulting in severe cord compression with peritumoral soft-tissue edema. The angiogram revealed a patent left vertebral artery entirely surrounded/encased by tumor. The PET-CT scan demonstrated no other spinal or systemic lesions. Due to his rapid neurological deterioration, the patient underwent an emergent biopsy of the tumor with posterior decompression and occipitocervical stabilization. The biopsy demonstrated a PNET (e.g., positive CD 99 MIC2 marker for Ewing’s sarcoma). Following subsequent chemotherapy and radiation, the patient rapidly improved over a period of 3 months.

Conclusion:
Primary Ewing’s sarcoma involving the C2 vertebra is exceedingly rare and warrants surgical decompression with pathological confirmation to provide additional multi-modal/multi-disciplinary adjunctive radiation/chemotherapy.
Migración de retorno y diversidad lingüística y cultural.
Authors: Huerta Córdova Vilma , López Gopar Mario Enrique , Sughrua William M. , León Jiménez Edwin Nazaret 
Published: October 2020

Este artículo, basado en un plan de estudios de formación docente de lenguas en la Universidad Autónoma “Benito Juárez” de Oaxaca, muestra cómo se atiende la migración de retorno (Estados Unidos a México). Los jóvenes que forman parte de este programa a través de la tutoría entre iguales, participan formando parejas (retornado con dominio del inglés y español deficiente y un local con dominio del español e inglés deficiente). Éstos preparan lecciones para ayudarse mutuamente con su lengua débil. En el área internacionales, es vital conocer estos programas para estudiar la migración de retorno a las comunidades de origen-destino.
PENGGUNAAN ALAT PERAGA WAYANG ALJABAR BERBASIS ANDROID UNTUK MENINGKATKAN KARAKTER DAN LITERASI SISWA
Authors: Uge Vransiska 
Published: October 2020

Pemanfaatan Wayang Aljabar Android dilator belakangi oleh rendahnya karakter dan literasi siswa dalam pembelajaran matematika. Tujuan penelitian adalah untuk meningkatkan karakter dan literasi siswa kelas VIID SMPN 3 Kalanganyar, Kabupaten Lebak, Provinsi Banten. Penelitian ini menggunakan rancangan Penelitian Tindakan Kelas dengan tiga siklus. Data dikumpulkan dalam setiap tahapan perencanaan, pelaksanaan tindakan, pengamatan dan penilaian, serta refleksi menggunakan tes, angket dan lembar observasi. Hasil belajar matematika dan sikap siswa dianalisis secara deskriptif kuantitatif. Hasil penelitian menunjukkan bahwa hasil belajar matematika siswa meningkat ketuntasan belajarnya dari 71, 4 %, 78, 6 %,menjadi 82, 1 % dalam tiga siklus. Rata-rata ketuntasan belajar siswa mencapai 73,8 di atas KKM. Keterampilan siswa juga menunjukkan peningkatan yang signifikan berturut-turut pada tiga kali penilaian memperoleh 77, 4 %, 78, 6 % dan 85, 4%. Dengan demikian dapat dijadikan suatu rekomendasi bahwa penggunaan alat peraga Wayang Aljabar berbasis Android dapat meningkatkan karakter dan literasi siswa.
Institutions, stakeholders and the city in the 2010s renaming policy in Russia
Authors: Lomakin Nikita 
Published: October 2020

The article presents an overview of the renaming tendencies in Russia of the 2010s and the main stakeholders of the name changing. On the base of the administration websites, online media petitions and other open sources, three cases are examined in detail: 1) Perm, where half of Maksim Gorky street was renamed after the surgeon Sergey Sukhanov in 2015; 2) Kazan, where at the same time Esperanto street was renamed after Nursultan Nazarbaev, causing mass protests for several years; 3) Volgograd, with the discussions about returning to its older name Stalingrad being led for years. Based on the analysis of these cases, the following tendencies are identified: changes of stakeholders motivation for renamings, transfer of power to name from parliamentary institutions to administration, a new perception of the city center and distant districts; and, finally, the appearance of alternative mechanisms of social memory encouraged by the wiping out of older names.
Molecular epidemiological typing of Neisseria gonorrhoeae isolates identifies a novel association between genogroup G10557 (G7072) and decreased susceptibility to cefixime, Germany, 2014 to 2017
Authors: Banhart Sebastian , Jansen Klaus , Buder Susanne , Tamminga Thalea , Calvignac-Spencer Sébastien , Pilz Tanja , Martini Andrea , Dudareva Sandra , Nikisins Sergejs , Dehmel Kerstin , Zuelsdorf Gabriele , Guhl Eva , Graeber Ingeborg , Kohl Peter K , Unemo Magnus , Bremer Viviane , Heuer Dagmar ,   on behalf of the GORENET study group
Published: October 2020

Background
Emerging antimicrobial resistance (AMR) challenges gonorrhoea treatment and requires surveillance.

Aim
This observational study describes the genetic diversity of Neisseria gonorrhoeae isolates in Germany from 2014 to 2017 and identifies N. gonorrhoeae multi-antigen sequence typing (NG-MAST) genogroups associated with AMR or some patient demographics.

Methods
1,220 gonococcal isolates underwent AMR testing and NG-MAST. Associations between genogroups and AMR or sex/age of patients were statistically assessed.

Results
Patients’ median age was 32 years (interquartile range: 25–44); 1,078 isolates (88.4%) originated from men. In total, 432 NG-MAST sequence types including 156 novel ones were identified, resulting in 17 major genogroups covering 59.1% (721/1,220) of all isolates. Genogroups G1407 and G10557 (G7072) were significantly associated with decreased susceptibility to cefixime (Kruskal–Wallis chi-squared: 549.3442, df: 16, p < 0.001). Their prevalences appeared to decline during the study period from 14.2% (15/106) to 6.2% (30/481) and from 6.6% (7/106) to 3.1% (15/481) respectively. Meanwhile, several cefixime susceptible genogroups’ prevalence seemed to increase. Proportions of isolates from men differed among genogroups (Fisher’s exact test, p < 0.001), being e.g. lower for G25 (G51) and G387, and higher for G5441 and G2992. Some genogroups differed relative to each other in affected patients’ median age (Kruskal–Wallis chi-squared:  47.5358, df:  16, p < 0.001), with e.g. G25 (G51) and G387 more frequent among ≤ 30 year olds and G359 and G17420 among ≥ 40 year olds.

Conclusion
AMR monitoring with molecular typing is important. Dual therapy (ceftriaxone plus azithromycin) recommended in 2014 in Germany, or only the ceftriaxone dose of this therapy, might have contributed to cefixime-resistant genogroups decreasing.
KNOWLEDGE AND PRACTISE REGARDING DOGS AND RABIES AMONG FULANI CATTLE HERDING COMMUNITIES IN ZARIA ENVIRONS, NIGERIA
Authors: Dzikwi  , Umoh  
Published: October 2020

Rabies is a viral disease transmitted mainly following the bite of a rabid dog. Dogs are increasingly being kept for security of livestock among cattle herders. The study was conducted to assess the knowledge, attitude and practise regarding dogs and rabies among the cattle herding community to identify gaps regarding knowledge of rabies transmission and plan intervention. Questionnaires were prepared and administered by face to face interview among members of the communities. Responses were scored based on a marking scheme and observations documented. There was poor knowledge and bad practise regarding rabies and dog ownership. Most of the dogs were not vaccinated against rabies. Furthermore, there was a practice of swapping dogs for household items among members of the community and dog dealers. This has grave implication because it will drive reckless dog ownership for the sole purpose of obtaining desired household items. This coupled with poor vaccination of dogs will lead to increased chances of rabies transmission. There is a need for educating this group on the role of dogs in rabies and vaccination of the dogs in the community.
RECRUITMENT AND SELECTION STRATEGIES OF PUBLIC SECTOR UNDERTAKINGS
Authors: U Sajeena 
Published: October 2020

This study examines the impact of recruitment and selection strategies of public sector undertaking .In the Indian context, Public sector or the PSEs primarily constitute the corporate bodies where 51% or more equity is held by the government, created under the special acts of legislature, or registered under the companies Act 1956.Primary data on various aspects of recruitment and selection were collected from the employees of different undertakings with the help of well framed questionnaire that was duly filled by the HRM officials and employees. This study highlight the emerging trends in the recruitment and selection strategies of public sector undertaking and the major obstacles that are being faced by the companies.
FISH DISEASE AS A MONITOR OF LAKE WATER POLLUTION
Authors: Dwivedi Bharti , Banerjee Suchitra 
Published: October 2020

One of the greatest problems that the world is facing today is of environmental pollution. Increasing with every passing year and causing grave and irreparable damage to the environment .potentially harmful substances e.g. pesticides, heavy metals and hydrocarbons are often released into the aquatic environment. When large quantities of pollutants are released in water there may be immediate impact as measured by large scale. Sudden mortalities of fishes and other aquatic organisms. Lower levels of discharge may results in accumulation of the pollutants in aquatic organism. The end results which may occur long after the pollutants have passed through the aquatic environment include reduced metabolism, damage of skin and gills. Current study shows that some of the diseases caused by virus, pseudomonas, flavobacterium resulted from generally adverse water quality i.e., higher than usual quantities of organic material, oxygen depletion, change in pH values and enhanced microbial populations some infections with Serratia and Yesinia may also well reflected contamination of water with domestic sewage e.g. leaking septic tank.
REDUCTION OF REAL POWER LOSS BY UNIFIED ALGORITHM
Authors: Lenin K. 
Published: October 2020

In this paper, we propose a new Unified Algorithm (UA) by combination of Variable mesh optimization algorithm (VMO) with Differential Evolution (DE) for solving reactive power problem. VMO has mainly three search operators, one for global exploration and two for local optima exploitation. DE is a simple yet commanding evolutionary algorithm for solving optimization problems. In all iteration VMO serve as the initial population of DE and obtains a population of more quality with this population VMO begins a new cycle. The proposed UA has been tested in standard IEEE 30 bus test system and simulation results show clearly about the better performance of the proposed algorithm in reducing the real power loss with control variables within the limits.
Artistic discussion of the subject matter of the Kathotia rock paintings
Authors: Pandey Anjali , Mishra Anjali 
Published: October 2020

Adi Man first embodied his thoughts and experiences through art. Through illustrating images of inner feelings and imaginations, he pioneered an innovative tradition that probably lasts forever. The sculptures drawn by human beings not only have knowledge of the true nature of the Tadugin culture, along with it they also show the creativity, creativity and artistic aptitude of the human.
आदि मानव ने अपने विचारों एवं अनुभूतियों को सर्वप्रथम कला के द्वारा मूर्त रूप प्रदान किया। अंतस् के भावों एवं कल्पनाओं की चित्रों के माध्यम से व्यंजना कर उसने संभवतः चिर्काल तक अक्षुण्ण रहने वाली अभिनव परम्परा का सूत्रपात किया। पुरा मानव द्वारा आरेखित शैलचित्रों द्वारा तद्युगीन संस्कृति के यथार्थ स्वरूप का ज्ञान तो होता ही है, इसके साथ ही इनसे आदि मानव की सृजनात्मकता, रचनाशीलता व कलात्मक अभिवृत्ति का भी द्योतन होता है।
A STUDY ON GROWTH AND DEVELOPMENT OF HEALTH INSURANCE IN INDIA IN THE POST PRIVATIZATION ERA
Authors: Rath Jyoti Prakash , Sahu Maheshwar 
Published: October 2020

Health Insurance in India emerges in the year 1999 with the introduction of IRDA bill in the floor of Parliament. In the post-privatization era, health insurance segment developed slowly and steadily. The penetration of insurance sector in Non-Life insurance is kept on increasing since 2001. In order to portray the journey of health insurance sector in India, it is required to show the growth and development of this sector in the country. The present study is intended to evaluate the growth and development of the health insurance sector in India in the post-privatization era. Data are collected mainly from secondary sources. Such data are analyzed and represented suitable through the help of tables, diagrams and charts. From the study, it is concluded that there is a significant upward trend in the growth of health insurance industry in India both at public and private sector after privatization. If this trend continues by keeping other factors constant, then the health insurance business would touch to Rs 20000 crores in the financial year 2016-17 contributed at least 60% by public sector and rest 40% by both private insurers and standalone health insurers.
EXPERIMENTAL STUDY AND PERFORMANCE OF SOLAR ENERGY SYSTEM WITH GRID CONNECTED POWER SUPPLY
Authors: Bharti Pradeep , Sharma A.K. 
Published: October 2020

In this paper , we are analyzed about the solar power with grid connection using of various component such as PV Cells battery inverter, and grid power connection , in this way we are connected the grid power and solar power , after that finally we are analyzed the power quality of output with the help of various devices.
TUMOR METASTASIS DILEMMA: BONE SCAN AND PSA LEVEL IN RELATION TO PROSTATIC MALIGNANCY AMONG SUDANESE
Authors: Mohamed Fahad A. , Abdallah Yousif M. Y. , Gar-elnabi Mohamed E.M. 
Published: October 2020

Observed the patient with prostate cancer during five years to measure the survival rate that for evaluating the effectiveness of diagnosis and treatment options.
This study conducted to study bone scan and PSA level and their relation to prostatic Malignancy among Sudanese.
This study is a retrospective cohort study, which was performed in Sudan. The sample magnitude was 306 prostate carcinoma patients with age ranged between 43-93 years. The patients' follow-up through 5 years studied in order to assess whether of them were alive or dead. The observed, corrected and expected five survival of the population were used. Kalban-Meier calculation methods of five years survival were used.
The study found that only 111 (36.3%) of the 306 patients animated 5 years afterward their dates of initial management and therefore, the 5 years survival rate is 37%. The study found that the survival rate were 37%, 42% and 44% (p > 0.05) respectively.
The study found that there were many factors affected the survival rate in Sudanese population such as treatment type and diagnosis date.