bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vertical stellar density distribution in a non-isothermal galactic disc
Authors: Sarkar Suchira , Jog Chanda J 
Published: September 2020

ABSTRACT
The vertical density distribution of stars in a galactic disc is traditionally obtained by assuming an isothermal vertical velocity dispersion of stars. Recent observations from SDSS, LAMOST, RAVE, Gaia etc. show that this dispersion increases with height from the mid-plane. Here, we study the dynamical effect of such non-isothermal dispersion on the self-consistent vertical density distribution for the thin disc stars in the Galaxy, obtained by solving together the Poisson equation and the equation of hydrostatic equilibrium. We find that in the non-isothermal case the mid-plane density is lower and the scale height is higher than the corresponding values for the isothermal distribution, due to higher vertical pressure, hence the distribution is vertically more extended. The change is $\sim \! 35 {{\ \rm per\ cent}}$ at the solar radius for a stars-alone disc for the typical observed linear gradient of +6.7 km s−1 kpc−1 and becomes even higher with increasing radii and increasing gradients explored. The distribution shows a wing at high z, in agreement with observations, and is fitted well by a double $\operatorname{sech}^{2}$, which could be mis-interpreted as the existence of a second, thicker disc, specially in external galaxies. We also consider a more realistic disc consisting of gravitationally coupled stars and gas in the field of dark matter halo. The results show the same trend but the effect of non-isothermal dispersion is reduced due to the opposite, constraining effect of the gas and halo gravity. Further, the non-isothermal dispersion lowers the theoretical estimate of the total mid-plane density i.e. Oort limit value, by 16 per cent.
A Galactic dust devil: far-infrared observations of the Tornado supernova remnant candidate
Authors: Chawner H , Howard A D P , Gomez H L , Matsuura M , Priestley F , Barlow M J , De Looze I , Papageorgiou A , Marsh K , Smith M W L , Noriega-Crespo A , Rho J , Dunne L 
Published: September 2020

ABSTRACT
We present complicated dust structures within multiple regions of the candidate supernova remnant (SNR) the ‘Tornado’ (G357.7–0.1) using observations with Spitzer and Herschel. We use point process mapping, ppmap, to investigate the distribution of dust in the Tornado at a resolution of 8 arcsec, compared to the native telescope beams of 5–36 arcsec. We find complex dust structures at multiple temperatures within both the head and the tail of the Tornado, ranging from 15 to 60 K. Cool dust in the head forms a shell, with some overlap with the radio emission, which envelopes warm dust at the X-ray peak. Akin to the terrestrial sandy whirlwinds known as ‘dust devils’, we find a large mass of dust contained within the Tornado. We derive a total dust mass for the Tornado head of 16.7 $\rm M_{\odot }$, assuming a dust absorption coefficient of κ300 = 0.56 $\rm m^2\, kg^{-1}$, which can be explained by interstellar material swept up by a SNR expanding in a dense region. The X-ray, infrared, and radio emission from the Tornado head indicate that this is a SNR. The origin of the tail is more unclear, although we propose that there is an X-ray binary embedded in the SNR, the outflow from which drives into the SNR shell. This interaction forms the helical tail structure in a similar manner to that of the SNR W50 and microquasar SS 433.
Velocity shift of Mg ii and Al iii broad absorption lines in quasar SDSS J134444.33+315007.6
Authors: Lu Wei-Jian , Lin Ying-Ru 
Published: September 2020

ABSTRACT
We report, for the first time, a synchronized velocity shift of Mg ii and Al iii broad absorption lines (BALs) in quasar SDSS J134444.33+315007.6 (hereafter, J1344+3150). We found this quasar from a sample of 134 Mg ii BAL quasars with multi-epoch observations. This quasar contains three low-ionization BAL systems, the fastest of which at ${\sim} -17\, 000\, \rm km\, s^{-1}$ shows a kinematic shift of ${\sim} -1101$ and $\sim -1170\, \rm km\, s^{-1}$ in its Mg ii and Al iii ions, respectively, during a rest-frame time of about 3.21 yr. Meanwhile, this quasar also shows other various variation characteristics, including an obvious weakening in its continuum, a coordinated enhancement in multiple emission lines (Mg ii, C iii, and Al iii), and a coordinated enhancement in three Al iii absorption troughs. These variation characteristics convincingly indicate that the BAL outflows of J1344+3150 are under the influence from the background radiation energy. Thus, we infer that the velocity shift displayed in system A in the quasar J1344+3150 may indicate an actual line-of-sight acceleration of an outflow due to the radiation pressure from the central source.
A crucial test of the phantom closed cosmological model
Authors: Shirokov S I , Baryshev Yu V 
Published: September 2020

ABSTRACT
We suggest a crucial direct-observational test for measuring distinction between the standard ΛCDM model and recently proposed phantom dark energy positive curvature cosmological model. The test is based on the fundamental distance–flux–redshift relation for general Friedmann models. It does not depend on the CMBR data, on the large-scale structure growth models, and also on the value of the Hubble constant H0. Our crucial test can be performed by future gamma-ray burst observations with THESEUS space mission and by using gravitational-wave standard siren observations with modern advanced LIGO–Virgo and also forthcoming LISA detectors.
R-chie: a web server and R package for visualizing cis and trans RNA–RNA, RNA–DNA and DNA–DNA interactions
Authors: Tsybulskyi Volodymyr , Mounir Mohamed , Meyer Irmtraud M 
Published: September 2020

Abstract
Interactions between biological entities are key to understanding their potential functional roles. Three fields of research have recently made particular progress: the investigation of transRNA–RNA and RNA–DNA transcriptome interactions and of trans DNA–DNA genome interactions. We now have both experimental and computational methods for examining these interactions in vivo and on a transcriptome- and genome-wide scale, respectively. Often, key insights can be gained by visually inspecting figures that manage to combine different sources of evidence and quantitative information. We here present R-chie, a web server and R package for visualizing cis and transRNA–RNA, RNA–DNA and DNA–DNA interactions. For this, we have completely revised and significantly extended an earlier version of R-chie (1) which was initially introduced for visualizing RNA secondary structure features. The new R-chie offers a range of unique features for visualizing cis and transRNA–RNA, RNA–DNA and DNA–DNA interactions. Particularly note-worthy features include the ability to incorporate evolutionary information, e.g. multiple-sequence alignments, to compare two alternative sets of information and to incorporate detailed, quantitative information. R-chie is readily available via a web server as well as a corresponding R package called R4RNA which can be used to run the software locally.
Integrating information in the brain’s EM field: the cemi field theory of consciousness
Authors: McFadden Johnjoe 
Published: September 2020

Abstract
A key aspect of consciousness is that it represents bound or integrated information, prompting an increasing conviction that the physical substrate of consciousness must be capable of encoding integrated information in the brain. However, as Ralph Landauer insisted, ‘information is physical’ so integrated information must be physically integrated. I argue here that nearly all examples of so-called ‘integrated information’, including neuronal information processing and conventional computing, are only temporally integrated in the sense that outputs are correlated with multiple inputs: the information integration is implemented in time, rather than space, and thereby cannot correspond to physically integrated information. I point out that only energy fields are capable of integrating information in space. I describe the conscious electromagnetic information (cemi) field theory which has proposed that consciousness is physically integrated, and causally active, information encoded in the brain’s global electromagnetic (EM) field. I here extend the theory to argue that consciousness implements algorithms in space, rather than time, within the brain’s EM field. I describe how the cemi field theory accounts for most observed features of consciousness and describe recent experimental support for the theory. I also describe several untested predictions of the theory and discuss its implications for the design of artificial consciousness. The cemi field theory proposes a scientific dualism that is rooted in the difference between matter and energy, rather than matter and spirit.
Ten-Year Outcomes of 1- and 2-Level Cervical Disc Arthroplasty From the Mobi-C Investigational Device Exemption Clinical Trial
Authors: Kim Kee , Hoffman Greg , Bae Hyun , Redmond Andy , Hisey Michael , Nunley Pierce , Jackson Robert , Tahernia David , Araghi Ali 
Published: September 2020

Abstract

BACKGROUND
Short- and mid-term studies have shown the effectiveness of cervical disc arthroplasty (CDA) to treat cervical disc degeneration.

OBJECTIVE
To report the 10-yr outcomes of a multicenter experience with cervical arthroplasty for 1- and 2-level pathology.

METHODS
This was a prospective study of patients treated with CDA at 1 or 2 contiguous levels using the Mobi-C® Cervical Disc (Zimmer Biomet). Following completion of the 7-yr Food and Drug Administration postapproval study, follow-up continued to 10 yr for consenting patients at 9 high-enrolling centers. Clinical and radiographic endpoints were collected out to 10 yr.

RESULTS
At 10 yr, patients continued to have significant improvement over baseline Neck Disability Index (NDI), neck and arm pain, neurologic function, and segmental range of motion (ROM). NDI and pain outcomes at 10 yr were significantly improved from 7 yr. Segmental and global ROM and sagittal alignment also were maintained from 7 to 10 yr. Clinically relevant adjacent segment pathology was not significantly different between 7 and 10 yr. The incidence of motion restricting heterotopic ossification at 10 yr was not significantly different from 7 yr for 1-level (30.7% vs 29.6%) or 2-level (41.7% vs 39.2%) patients. Only 2 subsequent surgeries were reported after 7 yr.

CONCLUSION
Our results through 10 yr were comparable to 7-yr outcomes, demonstrating that CDA with Mobi-C continues to be a safe and effective surgical treatment for patients with 1- or 2-level cervical degenerative disc disease.
Discordance Between Radiologic Findings and Molecular Testing in Patients With Underlying Hematologic Malignancy and Coronavirus Disease 2019
Authors: Raja Mohammed , Natori Yoichiro , Chandorkar Aditya , Camargo Jose F , Simkins Jacques , Andrews David , Bradley Terrence , Watts Justin , Komanduri Krishna , Morris Michele I , Fishman Joel E 
Published: September 2020

Abstract
Severe acute respiratory syndrome coronavirus 2 is associated with severe disease in patients with hematologic malignancy. We report a series of patients with underlying hematologic malignancy and coronavirus disease of 2019 with discrepancy between radiographic findings and molecular testing. Initial chest x-ray findings should raise suspicion in immunosuppressed patients with typical clinical presentation even with negative initial testing.
18F-FDG PET/CT contribution to tuberculous vertebral osteomyelitis diagnosis: a case report
Authors: Manika Katerina , Kipourou Maria , Georga Stamata , Faniadou Eleni , Pilianidis Georgios , Arsos Georgios , Kioumis Ioannis 
Published: September 2020

ABSTRACT
Tuberculous vertebral osteomyelitis (TVO) is an extrapulmonary tuberculosis form characterized by difficulty and delay in diagnosis. PET/CT is a valuable, well-established tool in the diagnostic workup of cancer and fever of unknown origin, which is increasingly appreciated in the management of infectious diseases. We report a TVO case where PET/CT had a valuable contribution towards diagnosis and monitoring of treatment response, highlighting its advantages and future perspectives when dealing with infectious diseases.
Homozygous familial hypercholesterolemia with an update on cholesterol management
Authors: Velvet Anju J J , Soran Handrean , Clarke Bernard , Motwani Manish , Ordoubadi Farzin F , Daniels Matthew J 
Published: September 2020

ABSTRACTFamilial hypercholesterolemia (FH) is an autosomal dominant condition that increases the risk of premature cardiovascular disease. Despite advances in treatment, it remains under detected and under treated. As an inherited condition, it poses a risk to the patient and family members. Most cases are due to defective low-density lipoprotein receptor (LDLR) activity. Heterozygous mutations are common (1:250–1:300). Homozygous FH is very rare (2–3 in a million), with higher circulating cholesterol levels and a poorer cardiovascular prognosis. We present the management of a case of homozygous hypercholesterolemia due to homozygous LDLR mutation. The patient subsequently developed severe coronary artery and aortic valve disease despite aggressive lipid-lowering therapy. We review advanced lipid management options that include lipoprotein apheresis, Proprotein Convertase Subtilisin/Kexin type 9 inhibition, and the microsomal triglyceride transfer protein inhibitor lomitapide.
Revising a diagnosis of functional neurological disorder—a case report
Authors: Berry Alex J , Wiethoff Sarah 
Published: September 2020

ABSTRACT
We report a case of a 62-year-old female diagnosed with functional neurological disorder (FND), where the diagnosis was eventually revised to progressive supranuclear palsy 3 years after symptom onset. FND is a commonly encountered condition and can be diagnosed with a considerable degree of confidence in most cases. FND is associated with significant functional impairment and may occur alongside other neurological disorders, and there is now a growing evidence base for symptom-specific FND treatments. Charting clinical progression of symptoms and serial neuroimaging were useful in refining the diagnosis in this case. Alhough the diagnosis was ultimately revised to a neurodegenerative disorder, a degree of functional overlay likely remained present. The case highlights the importance of recognizing and avoiding diagnostic overshadowing in those with FND.
An unusual headache: CSF negative APML relapse in the brain
Authors: Quinn Thomas , Jain Manish , Lee Ming-Te 
Published: September 2020

ABSTRACT
Acute Promyelocytic Leukaemia (APML) is a subtype of Acute Myeloid Leukaemia (AML), responsible for around 10% of cases of the disease in adults. Extra medullary disease (EMD) occurs infrequently in APML, but where EMD does occur, the central nervous system is one of the most commonly infiltrated sites. Our case describes a man in his 40s undergoing post-therapy surveillance for APML who presented to follow-up clinic with a headache, which was ultimately found to be caused by a tumour comprised of APML cells. His case presented a diagnostic challenge due to the benign appearances of the lesion on initial computed tomography brain imaging and the non-diagnostic cerebrospinal fluid analysis. The diagnostic difficulties described in our case emphasizes that clinicians working with APML patients must approach new neurological symptoms with a high degree of suspicion to prevent diagnostic delay.
Dermatopathia pigmentosa reticularis with beard alopecia: first report from Syria
Authors: Elias Lama , Bleidy Rahaf , Hasan Foz , Romeah Abdalhalem , Houreih Mohammad Adib 
Published: September 2020

ABSTRACT
Dermatopathia pigmentosa reticularis (DPR) is a rare disorder with characteristic triad of generalized reticulate hyperpigmentation, noncicatricial alopecia and onychodystrophy. We report the first case from Syria with classical features of the triad along with hyperhidrosis and adermatoglyphia. Based on previous studies this case is distinguished by the location of alopecia on the beard which is not reported before and distinctive histopathological features were found on the biopsy.
Primary vaginal leiomyosarcoma: case report of a rare gynaecological malignancy and diagnostic challenge in a resource-constraint setting
Authors: Okunowo Adeyemi A , Ugwu Aloy O , Owie Emmanuel , Kolawole Habibat F , Adebayo Luqman A , Kusamotu Olaniyi A , Kuku Jubril O , Soibi-Harry Adaiah P , Ohazurike Ephraim O , Banjo Adekunbiola A F 
Published: September 2020

ABSTRACTPrimary vaginal leiomyosarcoma (VLMS) is an extremely rare variant of primary vaginal cancers with very poor prognosis irrespective of the stage at presentation and the type of treatment received. It is easily recurrent and has a high propensity for haematogenous spread especially to the lungs. We present the case of a 34-year-old Para 1 + 1 (1 alive) woman with recurrent vaginal mass of 8 years duration after two surgical excisions without histological evaluation. She had examination under anaesthesia and a wide local excision of the vaginal mass. Histological examination of the mass revealed poorly differentiated VLMS with positive surgical margins and she was commenced on adjuvant chemo-radiation. Histological evaluation remains the hallmark for diagnosing rare malignancies like VLMS, which unfortunately is not a standard practice in some resource-constraint settings.
Teleology
Authors: McDonough Jeffrey K. 
Published: September 2020

Abstract
Teleology is the belief that some things happen, or exist, for the sake of other things. It is the belief that, for example, eyes are for seeing and gills are for breathing. It is the belief that people go to the cinema in order to see films and that salmon swim upstream in order to spawn. The core idea of teleology is thus intuitive enough. Nonetheless, difficult questions arise as we dig deeper into the concept. Is teleology intrinsic or extrinsic—that is, is teleology inherent in its subjects or is it imposed on them from the outside? Does teleology necessarily involve intentionality—that is, does teleology necessarily involve a subject’s cognizing some end, goal, or purpose? What is the scope of teleology—is the concept of teleology, for example, applicable to elements and animals, or only to rational beings? Finally, is teleology explanatory? When we say that salmon swim upstream in order to spawn, have we explained why they swim upstream? When we say that eyes are for seeing, have we explained why we have eyes? This volume explores the development of the concept of teleology from ancient times to the present. It begins in the golden age of ancient Greece with Plato and Aristotle, winds its way through Islamic, Latin, and Jewish medieval traditions, passes into treatments by leading figures of the scientific revolution, and European Enlightenment, and finishes with current debates in contemporary philosophy of biology. Chapter discussions of key figures, traditions, and contexts are enlivened and contextualized by a series of intermittent reflections on the implications of teleology in medicine, art, poetry and music.
Towards a dynamic disequilibrium theory with randomness
Authors: Guzman Martin , Stiglitz Joseph E 
Published: September 2020

AbstractThe 2008 Global Financial Crisis, and the myriad other crises confronting economies around the world, exposed the inadequacies of the Dynamic Stochastic General Equilibrium models. These models not only hadn’t predicted the crisis, its occurrence was completely outside of their framework. The framework assumes there are no macroeconomic inconsistencies—all plans are realized, all budget constraints honoured. But after each instance in which that assumption is proved wrong, say in a crisis, the DSGE models assume that kind of event won’t happen again. By contrast, our framework explains why these inconsistencies arise and investigates the consequences, shows how large changes in the aggregate demand could trigger inconsistencies, explains the origins of such changes, and explains why decentralized market forces may be disequilibrating. We identify the crucial departures from the Arrow–Debreu assumptions underlying our results. We analyse the policy implications of this alternative theory, which typically are distinctly different from those of the standard model.
What Are DPT Program Practices and Attitudes Related to Population Health, Prevention, Health Promotion, and Wellness? Results of a National Survey
Authors: Rethorn Zachary D , Maxwell Jessica L , Bezner Janet R , Davenport Todd E , Bradford Elissa H , Ingman Mary Sue , Magnusson Dawn M 
Published: September 2020

Abstract

Objective
Noncommunicable diseases have increased in prevalence and are now responsible for the majority of the burden of disease. Aligning entry-level (professional) physical therapist education with these changing societal needs may position physical therapists to best address them. However, no comprehensive understanding of the practices and attitudes related to population health, prevention, health promotion, and wellness (PHPW) content among accredited US professional doctor of physical therapy (DPT) programs has been established. This study aims to identify practices and attitudes related to PHPW content among accredited US DPT programs.

Methods
A mixed-methods cross-sectional design using an electronic survey was utilized. Program directors of each accredited DPT program were identified using an official Commission on Accreditation in Physical Therapy Education list and invited to ascertain the perceived importance of PHPW, describe the delivery of PHPW content, and identify factors that influence inclusion of PHPW content in US DPT programs.

Results
Individuals from 49% of 208 invited programs responded. Nearly all programs reported teaching prevention (96.1%), health promotion (95.1%), and wellness content (98.0%), while fewer reported teaching population health (78.4%). However, only 15% of PHPW topics were covered in depth. Facilitators and barriers to the delivery of PHPW content were reciprocal and included faculty with PHPW expertise, logistical flexibility and support, and the perceived importance of PHPW content.

Conclusions
The majority of US DPT programs are teaching PHPW content. Lack of trained faculty and lack of professional competencies hinder further integration of PHPW content into curricula.

Impact
The findings of this study highlight avenues for additional research to determine professional PHPW competencies and additional educational needs for faculty members.