bluuebunny/crossref_metadata_2025_split huggingface dataset:
Humanitarian reason and the movement for overdose prevention sites: The NGOization of the Opioid “Crisis”
Authors: Foth Thomas 
Published: August 2020

AbstractIn August 2017, a group of activists erected in Ottawa's downtown a tent as a first overdose prevention site as a response to what the public and the activists perceived as an epidemic—a devastating wave of opioid and fentanyl overdoses in Canada. The Ontario premier was urged to declare an emergency that would provide increased funding for harm reduction and also send a message to survivors and families that the lives of their loved ones mattered. Thus, the discourses around the so‐called opioid crisis used a language of moral sentiments to legitimate political action. This “new humanitarianism” is considered a priori as good, but in this article, I ask what is politically at stake if we base our actions on the logic of humanitarian reason. The new universalism of humanitarian organizations is based on the individualism of human rights and thus on a moral imperative that replaces the political. Initiatives like the OPS movement often fill the gaps in social services in the absence of the state and address social problems as emergencies and public health issues, thereby transforming them into medical problems—performing the medicalization of sociopolitical problems. This is what I call the NGOization of the opioid crisis. This form of humanitarianism is a universalism of the temporal present without any universal promise for a better future or the amelioration of human conditions—it is a humanitarianism of emergency. What characterizes new humanitarianism is that it responds to situations of suffering that are the result of increasing inequality and injustices without addressing the root causes of this suffering. Not addressing these causes means to be complicit in perpetuating the inequalities and to restrict visions of possible alternatives.
Modified Anatomic Locking Plate for the Treatment of Posteromedial Tibial Plateau Fractures
Authors: Jian Zhen , Ao Rong‐guang , Zhou Jian‐hua , Jiang Xin‐hua , Yu Bao‐qing 
Published: August 2020

ObjectiveTo evaluate the safety and clinical efficacy of a modified anatomic locking plate for the treatment of posteromedial tibial plateau fractures.MethodsA retrospective study was performed in our department. Between January 2014 and February 2017, 11 patients with posteromedial tibial plateau fractures underwent surgery with the new anatomic locking plate for the posteromedial tibial plateau via the posteromedial approach. The study included 7 male and 4 female patients, with a mean age at the time of the operation of 39 years. During surgery, operation time and blood loss were recorded. Clinical evaluation was performed using the Tegner–Lysholm functional score, the Rasmussen functional score, and the Rasmussen anatomical score.ResultsThe mean follow‐up time of the study was 35 months. The mean interval between the time of injury and the surgery was 7.4 days. Radiological fracture union was evident in all patients at 14 weeks. During surgery, the blood loss ranged from 50 to 150 mL, and the duration ranged from 55 to 90 min. The Tegner–Lysholm functional score ranged from 80 to 96 at the final follow up. Moreover, the final Rasmussen functional score ranged from 25 to 28, and the Rasmussen anatomical score ranged from 15 to 18. The mean knee arc of motion was 137° (range, 122°–153°). Symptoms of knee instability or severe pain were not found in any cases. No flexion contractures or extensor lag was seen. No infection, deep vein thrombosis, or graft site morbidity was seen at the follow up. No case of reduction loss or internal fixation failure was reported during the follow‐up.ConclusionWith the clinical data of the small‐sample‐size population (11 patients) during a 19 to 60‐month follow‐up, the modified anatomic locking plate for the posteromedial tibial plateau proved to be safe and effective and is an adequate fixation method for the treatment of posteromedial tibial plateau fractures.
Management of cardiac arrhythmias in patients with autoimmune disease—Insights from EHRA Young Electrophysiologists
Authors: Gawałko Monika , Peller Michał , Balsam Paweł , Grabowski Marcin , Kosiuk Jędrzej 
Published: August 2020

AbstractBackgroundSince arrhythmia treatment in patients with autoimmune disease (AD) is challenging, we aimed to assess the common “real‐world” practice in the electrophysiology centers.MethodsTwenty‐four young electrophysiologists being part of European Heart Rhythm Association filled questionnaire regarding arrhythmia management in AD.ResultsRheumatoid arthritis was the most commonly reported AD accompanied by cardiac arrhythmias. The most frequent observed arrhythmias were atrial fibrillation and premature atrial/ventricular contractions. Most often electrocardiographic abnormalities observed were increased heart rate variability, QT interval prolongation, and P‐wave dispersion, whereas echocardiographic abnormalities included left atrial enlargement, pericardial infusion, and left ventricular dysfunction. The most useful tool for arrhythmia management was guidelines and evidence‐based medicine, while training courses and websites were at least useful. A close collaboration with other specialists in arrhythmia management was reported in 58.3% of respondents. Glucocorticoids and cytostatic were the most reported arrhythmia‐induced drugs, whereas amiodarone and beta‐blockers were most effective antiarrhythmic drugs. The main reason that discouraged respondents from cardiac implantable devices implantation and catheter ablation was high infection complications risk and recurrences during long‐term follow‐up, respectively.ConclusionsScant data and guidelines enforce exchange of experience to improve the arrhythmia treatment in AD.
Can serum periostin, YKL‐40, and osteopontin levels in pre‐school children with recurrent wheezing predict later development of asthma?
Authors: Guvenir Hakan , Buyuktiryaki Betul , Kulhas Celik Ilknur , Civelek Ersoy , Kilic Suloglu Aysun , Karaaslan Cagatay , Genc Selcan , Dibek Misirlioglu Emine , Toyran Muge , Ginis Tayfur , Kocabas Can N. 
Published: August 2020

AbstractBackgroundCurrently, there are no reliable clinical tools available for predicting asthma in pre–school‐aged children with recurrent wheezing. The aim of this study was to evaluate the usefulness of serum periostin, YKL‐40, and osteopontin biomarkers in wheezy pre–school‐aged children for predicting the development of asthma in school ages.MethodsThe study was prospectively conducted between 2011 and 2017. The clinical features of the pre–school‐aged children with recurrent wheezing and the levels of serum periostin, YKL‐40, and osteopontin were measured. The same participants were reevaluated in school‐age period, and participants with asthma were identified. Relative risk (RR) for the development of asthma was analyzed.ResultsOf the 197 pre–school‐aged children with recurrent wheezing who were reevaluated in school‐age years, 32% of them had asthma. Serum periostin, YKL‐40, and osteopontin levels at admission could not predict participants who would have asthma symptoms in school‐age years. The RR for continuing of asthma symptoms was higher in participants who had their first wheezing episode before 1 year of age, preterm birth, cesarean section delivery, prenatal smoking exposure, multi‐trigger wheezing, parental asthma, modified asthma predictive index positivity, prophylactic vitamin D intake ≤ 12 months, breastfeeding time ≤ 12 month, and aeroallergen sensitivity [RR (95% CI) and P value: 2.813 (1.299‐6.091), 0.002; 1.972 (1.274‐3.052), 0.009; 1.929 (1.195‐3.114), 0.004; 2.232 (1.463‐3.406), <0.001; 3.152 (1.949‐5.097), <0.001; 1.730 (1.144‐2.615), 0.016; 2.427 (1.559‐3.777), <0.001; 2.955 (1.558‐5.604), <0.001; 1.767 (1.084‐2.881), 0.016; 0.765 (0.556‐1.053), 0.016; respectively].ConclusionResults have shown that clinical features were more valuable than biomarkers in predicting having asthma in school‐age years in participants who had recurrent wheezing in pre–school‐age period.
Dissection of identical‐by‐descent segments during the formation of foundation parents derived from Suwan germplasm of maize
Authors: Guo Xiangyang , Wu Xun , Wu Wenqiang , Wang Angui , Liu Pengfei , Zhu Yunfang , Ren Hong , Chen Zehui , Luo Hongbing 
Published: August 2020

AbstractSuwan germplasm plays important roles in maize breeding in tropical/subtropical regions, especially in southern China. To analyze the genetic characteristics of Suwan maize germplasm, one panel of 73 lines derived from the Suwan population and temperate resources were collected and genotyped using 56,110 single‐nucleotide polymorphism (SNP) markers. The results revealed four subgroups, namely, QR273, Ki32, HCL645, and PH4CV, with an average genetic distance of 0.304, varying from 0.001 to 0.370. In addition, many identical‐by‐descent (IBD) segments were found among Suwan germplasms and their descendants, of which 78 segments were detected only in the QR273 subgroup, 18 segments were detected only in the Ki32 subgroup, 53 and 11 segments were detected only in the PH4CV and the HCL645 subgroup, respectively. Pairwise comparisons showed that 13 segments were common between the QR273 and Ki32 subgroups, 5 segments were common between the QR273 and HCL645 subgroups, 26 segments were common between the QR273 and PH4CV subgroups. Five and 14 segments were common between the Ki32 versus HCL645 subgroups and Ki32 versus PH4CV subgroups. Three segments were commonly detected in the Ki32, QR273, and HCL645 subgroups. Candidate gene analysis showed that 132 genes were located in these segments, wherein seven new candidate genes were associated with flower time (FT)‐related traits, which were located in the IBD segments of QR273 or HCL645. Zm00001d033130_T005 and Zm00001d013768_T001 were located in the IBD segments specific to the QR273 subgroup. These two genes function in cell differentiation and flower development and would be very important for the phenotypic variations of the given FP subgroups. These results provide new insights and scientific proof for dissecting the genetic basis of complex traits and the utilization of Suwan germplasm in future maize breeding.
Evaluation of a commercial intravaginal thermometer to predict calving in a Hungarian Holstein‐Friesian dairy farm
Authors: Choukeir Ali Ismael , Kovács Levente , Kézér Luca Fruzsina , Buják Dávid , Szelényi Zoltán , Abdelmegeid Mohamed Kamel , Gáspárdy András , Szenci Ottó 
Published: August 2020

AbstractIn this study, the utility of a commercial intravaginal thermometer was evaluated as an automated method for the prediction of calving in a total of 257 healthy pregnant Holstein–Friesian female cattle. The accuracy and the sensitivity of predicting calving within 48 hr before calving were also evaluated. The intravaginal temperature changes from 72 hr before and up to calving were significantly (p ≤ .001) affected by parity, season (summer vs. autumn), the time of day (8 a.m. or 8 p.m.) and the 6‐hr time intervals (38.19°C: first interval 0 to 6 hr before calving vs. 38.78°C: twelfth interval 66 to 72 hr before calving), while the gender (p = .943), and the weight of the calf (p = .610), twinning (p = .300), gestation length (p = .186), foetal presentation (p = .123), dystocia (p = .197) and retention of foetal membranes (p = .253) did not affect it significantly. The sensitivity of the SMS of expecting calving within 48 hr and the positive predictive value were 62.4% and 75%, respectively, while the sensitivity and the positive predictive value for the SMS of expulsion reached 100%. It can be concluded that the investigated thermometer is not able to predict calving within 48 hr accurately; however, imminent calving can be accurately alerted.
Using candidacy theory to explore unemployed over‐50s perceptions of suitability of a welfare to work programme: A longitudinal qualitative study
Authors: Neary Joanne , Katikireddi Srinivasa V. , McQuaid Ronald W. , Macdonald Ewan B. , Thomson Hilary 
Published: August 2020

AbstractWelfare to work interventions seek to move out‐of‐work individuals from claiming unemployment benefits towards paid work. However, previous research has highlighted that for over‐50s, particularly those with chronic health conditions, participation in such activities are less likely to result in a return to work. Using longitudinal semi‐structured interviews, we followed 26 over‐50s during their experience of a mandated welfare to work intervention (the Work Programme) in the United Kingdom. Focusing on their perception of suitability, we utilise and adapt Candidacy Theory to explore how previous experiences of work, health, and interaction with staff (both in the intervention, and with healthcare practitioners) influence these perceptions. Despite many participants acknowledging the benefit of work, many described a pessimism regarding their own ability to return to work in the future, and therefore their lack of suitability for this intervention. This was particularly felt by those with chronic health conditions, who reflected on difficulties with managing their conditions (e.g., attending appointments, adhering to treatment regimens). By adapting Candidacy Theory, we highlighted the ways that mandatory intervention was navigated by all the participants, and how some discussed attempts to remove themselves from this intervention. We also discuss the role played by decision makers such as employment‐support staff and healthcare practitioners in supporting or contesting these feelings. Findings suggest that greater effort is required by policy makers to understand the lived experience of chronic illness in terms of ability to RTW, and the importance of inter‐agency work in shaping perceptions of those involved.
Housing (In)Equity and the Spatial Dynamics of Homeownership in France: A Research Agenda
Authors: Le Goix Renaud , Casanova Enault Laure , Bonneval Loïc , Le Corre Thibault , Benites‐Gambirazio Eliza , Boulay Guilhem , Kutz William , Aveline‐Dubach Natacha , Migozzi Julien , Ysebaert Ronan 
Published: August 2020

AbstractThis paper advances a research agenda on how asset‐based welfare policies, residential market volatility, stratified accumulation and vulnerability impinge upon the geography of inequality in property markets. Since the mid‐1990s, housing prices have increased faster than the income of buyers, becoming a driver of social polarisation and household vulnerability. Few studies have however explicitly linked socio‐spatial inequality to asset capitalisation, instability and vulnerability in residential housing markets. We employ an empirically‐grounded investigation of the factors driving and reinforcing these dynamics, what we conceptualise as a feedback loop mediating particular housing finance regimes. Drawing on three French cities (Paris, Lyon, and Avignon) our study develops a comparative framework to interpret the relational effects of price, equity and homeowner vulnerability on the production of inequality across different geographical scales. Our approach puts into conversation debates concerning housing markets, social inequality, and ordinary financialisation in the period since the Global Financial Crisis.
Multiple linear regression: Identify potential health care stocks for investments using out‐of‐sample predictions
Authors: Kieu Thinh , Luu Phong , Yoon Noah 
Published: August 2020

AbstractCollege‐level statistics courses emphasize the use of the coefficient of determination, R‐squared, in evaluating a linear regression model: higher R‐squared is better. This often gives students an impression that higher R‐squared implies better predictability since textbooks tend to use sample data to support the theory and students rarely have an opportunity to work on real data. In this paper, health care stocks are used as predictors and the result demonstrates that high R‐squared does not necessarily mean high predictability and that multiple linear regression can be used in the study of data behavior. In particular, by learning the pattern of the near and far out‐of‐sample‐prediction errors for different time periods throughout a dataset, the near out‐of‐sample prediction errors can be used to control the prediction errors and identify a subset of predictors that can well reflect the trend of S&P 500.
Tensile strength and early healing of self‐locking and surgeon's knots
Authors: Weatherall Kathleen M. , Boone Lindsey H. , Caldwell Fred J. , Cole Robert C. , Cattley Russell C. , Lascola Kara M. , Clark‐Price Stuart C. , Farag Ramsis , Perkins Edmon , Hanson R. Reid 
Published: August 2020

AbstractObjectiveTo compare the biomechanical properties and healing of ventral midline celiotomies (VMC) closed with a self‐locking knot combination and forwarder start and Aberdeen end (F‐A) vs a traditional knot combination and surgeon's start and end (S‐S).Study designIn vivo, experimental.AnimalsTwenty‐one horses.MethodsFourteen horses underwent VMC, which was closed with either an F‐A (n = 7) or an S‐S (n = 7) knot combination. Incisions were subjectively graded by masked evaluators for dehiscence, edema, and drainage. Biomechanical testing was performed on three abdominal segments, and histology was performed on one segment from each animal after humane euthanasia 10 days post‐VMC. The abdominal wall of control horses (n = 7, no celiotomy) was collected for biomechanical testing.ResultsForwarder start and Aberdeen end and S‐S horses had less tensile strength compared with control horses (P ≤ .001). No differences were detected between treatment groups for any variable evaluated, including tensile strength (P = .975), location of failure (P = .240), and histologic healing at the knot (P = .600).ConclusionClosure of VMC with self‐locking knots resulted in biomechanical and healing features similar to those with a traditional closure technique, with neither restoring the tensile strength of the linea alba.Clinical significanceResults of this study provide evidence to support a clinical trial to evaluate long‐term performance of the F‐A self‐locking knot closure in horses.
Associations Among Physical Activity Level and Skeletal Muscle Antioxidants in Older Adults
Authors: Timmerman Kyle L. , Ballard Kevin D. , Deal Michael A. , Tagariello Lisa C. , Karrow Jenna M. , Volk Gabrielle A. , Meisler Adam , Connors Ian D. , Mott Rachael E. 
Published: August 2020

Background: Endogenous antioxidants are critical to limiting cellular oxidative damage. Methods: The authors determined if habitual physical activity (PA) and cardiorespiratory fitness were associated with skeletal muscle expression of endogenous antioxidants (superoxide dismutase, catalase, and glutathione peroxidase) and circulating oxidative stress markers (serum 8-hydroxy-2′-deoxyguanosine [8-OHdG]; oxidized low-density lipoprotein [LDL]) in older adults. Moderate to vigorous PA (MVPA) was estimated using a validated PA questionnaire in 26 older adults (mean [SD]; M/F = 9/17, age = 68 [4] y, body mass index = 26 [3] kg·m−2). Maximal oxygen consumption was estimated using the YMCA submaximal cycle test. Skeletal muscle endogenous antioxidants and serum 8-OHdG and oxidized LDL were measured. Bivariate and partial correlations (controlling for body mass index) were utilized to determine associations among variables. Results: MVPA (1640 [1176] kcal·wk−1) was correlated with superoxide dismutase 2 (r = .55), catalase (r = .55), glutathione peroxidase 1 (r = .48), and 8-OHdG (r = −.41) (all Ps < .05), but not oxidized LDL. MVPA and 8-OHdG were not significantly correlated when controlling for body mass index (r = −.29). Estimated maximal oxygen consumption was correlated with glutathione peroxidase 1 (r = .48; P < .05). Conclusions: These data show that skeletal muscle endogenous antioxidant expression and circulating oxidative damage are associated with habitual MVPA in older adults. Thus, MVPA in older adults may be protective against reactive oxygen species damage due to higher expression of endogenous antioxidants.
Chapter 5: Using Social Media: One Physical Education Teacher’s Experience
Authors: Brooks Collin C. , McMullen Jaimie M. 
Published: August 2020

Purpose: This study explored one physical education teacher’s engagement in an online professional learning community and her perceptions of its impact on her own feelings of isolation. Sense of community theory was used as a lens to explore the data. Method: Using a single instrumental case study design, the participant of this study was a female physical education teacher. The data were collected through semistructured interviews, public tweets (Twitter), and informal participant communication (Voxer). The data were analyzed using categorical aggregation, and codes with similar meanings were combined to develop themes. Results: Three themes were evident across data sources that represented her perceptions of participation in an online professional learning community: (a) taking initiative, (b) different support systems, and (c) stages of social media participation. Conclusion: Social media can provide a sense of community for physical education teachers, allowing them to feel less isolated.
Does the Spraino low-friction shoe patch prevent lateral ankle sprain injury in indoor sports? A pilot randomised controlled trial with 510 participants with previous ankle injuries
Authors: Lysdal Filip Gertz , Bandholm Thomas , Tolstrup Janne Schurmann , Clausen Mikkel Bek , Mann Stephanie , Petersen Pelle Baggesgaard , Grønlykke Thor Buch , Kersting Uwe G , Delahunt Eamonn , Thorborg Kristian 
Published: August 2020

BackgroundLateral ankle sprains are common in indoor sports. High shoe–surface friction is considered a risk factor for non-contact lateral ankle sprains. Spraino is a novel low-friction patch that can be attached to the outside of sports shoes to minimise friction at the lateral edge, which could mitigate the risk of such injury. We aimed to determine preliminary effectiveness (incidence rate and severity) and safety (harms) of Spraino to prevent lateral ankle sprains among indoor sport athletes.MethodsIn this exploratory, parallel-group, two-arm pilot randomised controlled trial, 510 subelite indoor sport athletes with a previous lateral ankle sprain were randomly allocated (1:1) to Spraino or ‘do-as-usual’. Allocation was concealed and the trial was outcome assessor blinded. Match and training exposure, number of injuries and associated time loss were captured weekly via text messages. Information on harms, fear-of-injury and ankle pain was also documented.Results480 participants completed the trial. They reported a total of 151 lateral ankle sprains, of which 96 were categorised as non-contact, and 50 as severe. All outcomes favoured Spraino with incidence rate ratios of 0.87 (95% CI 0.62 to 1.23) for all lateral ankle sprains; 0.64 (95% CI 0.42 to 0.98) for non-contact lateral ankle sprains; and 0.47 (95% CI 0.25 to 0.88) for severe lateral ankle sprains. Time loss per injury was also lower in the Spraino group (1.8 vs 2.8 weeks, p=0.014). Six participants reported minor harms because of Spraino.ConclusionCompared with usual care, athletes allocated to Spraino had a lower risk of lateral ankle sprains and less time loss, with only few reported minor harms.Trial registration numberNCT03311490.