bluuebunny/crossref_metadata_2025_split huggingface dataset:
An assessment of post-harvest fish losses and preservation practices in Siavonga district, Southern Zambia
Authors: Maulu Sahya , Hasimuna Oliver J. , Monde Concilia , Mweemba Malawo 
Published: September 2020

Abstract
Fish is an extremely perishable food product which requires proper handling soon after harvest. The present study was aimed at assessing post-harvest fish losses and preservation practices in Siavonga district, Southern Zambia. Structured and semi-structured questionnaires were used to collect data on post-harvest fish losses and preservation practices from aquaculture producers, artisanal, and commercial fishers. All the fishers who landed on the lakeshore were interviewed, while aquaculture producers were randomly selected based on the information provided by the local department of fisheries. The results of the study revealed that all the fishers experienced post-harvest fish losses at varying degrees with those losing up to 10% of the total catch being in the majority. In contrast, aquaculture producers did not report any post-harvest fish losses. Most aquaculture producers commonly used chilling as preservation practice contrary to artisanal and commercial fishers who commonly used smoking and sun sun-drying respectively. Furthermore, fish product safety and quality control were poorly practiced in the district. Lack of cold storage facilities and fluctuating weather conditions were the major challenges impacting fish post-harvest activities. Therefore, to curb the loss of revenue due to post-harvest fish losses, we propose the introduction of new technology, self-development skills for fishing communities, and enhanced access to refrigeration facilities.
Design of a robust PID-PSS for an uncertain power system with simplified stability conditions
Authors: A.S.V Vijaya Lakshmi , Manyala Ramalinga Raju , Mangipudi Siva Kumar 
Published: September 2020

AbstractIn a deregulated power system uncertainty exists and lack of sufficient damping can lead to Low Frequency Oscillations (LFO). The problem can be addressed using robust Power System Stabilizers (PSS). In this paper, an optimal procedure to design a robust PID-PSS using interval arithmetic for the Single Machine Infinite Bus (SMIB) power system is proposed. The interval modelling captures the wide variations of operating conditions in bounds of system coefficients. In the proposed design procedure, simple and new closed loop stability conditions for an SMIB interval system are developed and are used to design an optimum PID-PSS for improving the performance of an SMIB system. The optimum PID-PSS is attained by tuning the parameters using the FMINCON tool provided in MATLAB. The robustness of the proposed PID-PSS design is validated and compared to other notable methods in the literature when the system is subjected to different uncertainties. The simulation results and performance error values show the effectiveness of the proposed robust PID-PSS controller.
Validation of a German version of the Cerebellar Cognitive Affective/ Schmahmann Syndrome Scale: preliminary version and study protocol
Authors: Thieme Andreas , Roeske Sandra , Faber Jennifer , Sulzer Patricia , Minnerop Martina , Elben Saskia , Jacobi Heike , Reetz Kathrin , Dogan Imis , Barkhoff Miriam , Konczak Juergen , Wondzinski Elke , Siebler Mario , Mueller Oliver , Sure Ulrich , Schmahmann Jeremy D. , Klockgether Thomas , Synofzik Matthis , Timmann Dagmar 
Published: September 2020

Abstract
Background
Traditionally, cerebellar disorders including ataxias have been associated with deficits in motor control and motor learning. Since the 1980’s growing evidence has emerged that cerebellar diseases also impede cognitive and affective processes such as executive and linguistic functions, visuospatial abilities and regulation of emotion and affect. This combination of non-motor symptoms has been named Cerebellar Cognitive Affective/ Schmahmann Syndrome (CCAS). To date, diagnosis relies on non-standardized bedside cognitive examination and, if available, detailed neuropsychological test batteries. Recently, a short and easy applicable bedside test (CCAS Scale) has been developed to screen for CCAS. It has been validated in an US-American cohort of adults with cerebellar disorders and healthy controls. As yet, the CCAS Scale has only been available in American English. We present a German version of the scale and the study protocol of its ongoing validation in a German-speaking patient cohort.

Methods
A preliminary German version has been created from the original CCAS Scale using a standardized translation procedure. This version has been pre-tested in cerebellar patients and healthy controls including medical experts and laypersons to ensure that instructions are well understandable, and that no information has been lost or added during translation. This preliminary German version will be validated in a minimum of 65 patients with cerebellar disease and 65 matched healthy controls. We test whether selectivity and sensitivity of the German CCAS Scale is comparable to the original CCAS Scale using the same cut-off values for each of the test items, and the same pass/ fail criteria to determine the presence of CCAS. Furthermore, internal consistency, test-retest and interrater reliability will be evaluated. In addition, construct validity will be tested in a subset of patients and controls in whom detailed neuropsychological testing will be available. Secondary aims will be examination of possible correlations between clinical features (e.g. disease duration, clinical ataxia scores) and CCAS scores.

Perspective
The overall aim is to deliver a validated bedside test to screen for CCAS in German-speaking patients which can also be used in future natural history and therapeutic trials.

Study registration
The study is registered at the German Clinical Study Register (DRKS-ID: DRKS00016854).
Prevalence and predictors of aortic root abscess among patients with left-sided infective endocarditis: a cross-sectional comparative study
Authors: Mahmoud Kareem , Hammouda Tarek , Kandil Hossam , Mashaal Marwa 
Published: September 2020

Abstract
Background
Aortic root abscess (ARA) is a major complication of infective endocarditis that is associated with increased morbidity and mortality. Limited data are present about patient characteristics and outcomes in this lethal disease. We aimed to study the clinical and echocardiographic characteristics of patients with ARA compared to patients with left-sided infective endocarditis without ARA. We included patients with a definite diagnosis of left-sided infective endocarditis according to modified Duke’s criteria. The patients were classified into two groups according to the presence of ARA (ARA and NO-ARA groups). All the patients were studied regarding their demographic data, clinical characteristics, laboratory and imaging data, and complications.

Results
We included 285 patients with left-sided infective endocarditis. The incidence of ARA was 21.4% (61 patients). Underlying heart disease, mechanical prosthesis, bicuspid aortic valve, and prior IE were significantly higher in ARA. The level of CRP was higher in ARA (p = 0.03). ARA group showed more aortic valve vegetations (73.8% vs. 37.1%, p < 0.001), more aortic paravalvular leakage (26.7% vs. 4.5%, p < 0.001), and less mitral valve vegetations (21.3% vs. 68.8%, p < 0.001). Logistic regression analysis showed that the odds of ARA increased in the following conditions: aortic paravalvular leak (OR 3.9, 95% CI 1.2–13, p = 0.03), mechanical prosthesis (OR 3.6, 95% CI 1.5–8.7, p = 0.005), aortic valve vegetations (OR 3.0, 95% CI 1.2–8.0, p = 0.02), and undetected organism (OR 2.3, 95% CI 1.1–4.6, p = 0.02), while the odds of ARA decreased with mitral valve vegetations (OR 0.2, 95% CI 0.08–0.5, p = 0.001). We did not find a difference between both groups regarding the incidence of major complications, including in-hospital mortality.

Conclusion
In our study, ARA occurred in one fifth of patients with left-sided IE. Patients with mechanical prosthesis, aortic paravalvular leakage, aortic vegetations, and undetected organisms had higher odds of ARA, while patients with mitral vegetations had lower odds of ARA.
Mortality characteristics in Sudan in national psychiatric hospitals: 5-year review of hospital mortality
Authors: Osman Abdelgadir H. , Abdalhai Khalid A. , Hassan Israa , Elmubark Mohammed A. , Elawad Lubaba A. 
Published: September 2020

Abstract
Background
Re-auditing mortality of inpatient psychiatric service for a span of time extending to 14 years is scarce in low-resource countries. We are reporting a 5-year mortality study to complete an audit cycle with a previous 9-year mortality research published a few years ago. It serves to improve the standard of care in low-resource settings.

Results
Out of a total of 7340 (4890 men and 2450 women) admissions to all national psychiatric hospitals in Khartoum over a 5-year period, 36 (23 men and 13 women) patients died while receiving inpatient psychiatric treatment. The mortality rate in this sample was 4.9 (4.7 for men and 5.3 for women). Among all deaths, 30.6% were diagnosed with schizophrenia, while mania constituted 25%, major depression 15% and organic psychosis 11.3%, and 11.1% were considered to be due to alcohol- and/or drug-related disorders. There was no single case of unnatural death in this sample.
Twenty patients (55.6%) died following circulatory failure (sudden death), four (11.1%) as a result of an infection, three (8.3%) from renal failure, two (5.6%) secondarily to NMS, two (5.6%) from diabetic complications and four patients as a result of ECT, GIT bleeding, ischaemic heart disease and alcohol complications.

Conclusion
Circulatory failure and infection are the main causes of death in psychiatric hospitals in Sudan, calling for an intense investigation to resolve these preventable problems.
Dickkopf-1 Can Lead to Immune Evasion in Metastatic Castration-Resistant Prostate Cancer
Authors: Wise David R. , Schneider Jeffrey A. , Armenia Joshua , Febles Victor Adorno , McLaughlin Bridget , Brennan Ryan , Thoren Katie L. , Abida Wassim , Sfanos Karen S. , De Marzo Angelo M. , Yegnasubramanian Srinivasan , Fox Josef J. , Haas Michael , Heath Heidi , Kagey Michael H. , Newman Walter , Sirard Cynthia A. , Fleisher Martin , Morris Michael J. , Chen Yu , Larson Steven M. , Haffner Michael C. , Nelson Peter S. , Schultz Nikolaus , Garabedian Michael J. , Scher Howard I. , Logan Susan K. , Sawyers Charles L. ,   for the International SU2C/PCF Prostate Cancer Dream Team
Published: September 2020

PURPOSE Metastatic castration-resistant prostate cancer (mCRPC) with low androgen receptor (AR) and without neuroendocrine signaling, termed double-negative prostate cancer (DNPC), is increasingly prevalent in patients treated with AR signaling inhibitors and is in need of new biomarkers and therapeutic targets. METHODS Candidate genes enriched in DNPC were determined using differential gene expression analysis of discovery and validation cohorts of mCRPC biopsies. Laboratory studies were carried out in human mCRPC organoid cultures, prostate cancer (PCa) cell lines, and mouse xenograft models. Epigenetic studies were carried out in a rapid autopsy cohort. RESULTS Dickkopf-1 (DKK1) expression is increased in DNPC relative to prostate-specific antigen (PSA)–expressing mCRPC in the Stand Up to Cancer/Prostate Cancer Foundation discovery cohort (11.2 v 0.28 reads per kilobase per million mapped reads; q < 0.05; n = 117) and in the University of Washington/Fred Hutchinson Cancer Research Center cohort (9.2 v 0.99 fragments per kilobase of transcript per million mapped reads; P < .0001). DKK1 expression can be regulated by activated Wnt signaling in vitro and correlates with activating canonical Wnt signaling mutations and low PSA mRNA in mCRPC biopsies ( P < .05). DKK1 hypomethylation was associated with increased DKK1 mRNA expression (Pearson r = −0.66; P < .0001) in a rapid autopsy cohort (n = 7). DKK1-high mCRPC biopsies are infiltrated with significantly higher numbers of quiescent natural killer (NK) cells ( P < .005) and lower numbers of activated NK cells ( P < .0005). Growth inhibition of the human PCa model PC3 by the anti-DKK1 monoclonal antibody DKN-01 depends on the presence of NK cells in a severe combined immunodeficient xenograft mouse model. CONCLUSION These results support DKK1 as a contributor to the immunosuppressive tumor microenvironment of DNPC. These data have provided the rationale for a clinical trial targeting DKK1 in mCRPC (ClinicalTrials.gov identifier: NCT03837353 ).
Differential physiological roles for BIN1 isoforms in skeletal muscle development, function and regeneration
Authors: Prokic Ivana , Cowling Belinda S. , Kutchukian Candice , Kretz Christine , Tasfaout Hichem , Gache Vincent , Hergueux Josiane , Wendling Olivia , Ferry Arnaud , Toussaint Anne , Gavriilidis Christos , Nattarayan Vasugi , Koch Catherine , Lainé Jeanne , Combe Roy , Tiret Laurent , Jacquemond Vincent , Pilot-Storck Fanny , Laporte Jocelyn 
Published: September 2020

ABSTRACT
Skeletal muscle development and regeneration are tightly regulated processes. How the intracellular organization of muscle fibers is achieved during these steps is unclear. Here, we focus on the cellular and physiological roles of amphiphysin 2 (BIN1), a membrane remodeling protein mutated in both congenital and adult centronuclear myopathies (CNM), that is ubiquitously expressed and has skeletal muscle-specific isoforms. We created and characterized constitutive muscle-specific and inducible Bin1 homozygous and heterozygous knockout mice targeting either ubiquitous or muscle-specific isoforms. Constitutive Bin1-deficient mice died at birth from lack of feeding due to a skeletal muscle defect. T-tubules and other organelles were misplaced and altered, supporting a general early role for BIN1 in intracellular organization, in addition to membrane remodeling. Although restricted deletion of Bin1 in unchallenged adult muscles had no impact, the forced switch from the muscle-specific isoforms to the ubiquitous isoforms through deletion of the in-frame muscle-specific exon delayed muscle regeneration. Thus, ubiquitous BIN1 function is necessary for muscle development and function, whereas its muscle-specific isoforms fine tune muscle regeneration in adulthood, supporting that BIN1 CNM with congenital onset are due to developmental defects, whereas later onset may be due to regeneration defects.
Retrospective quality assurance audit of Lateral Cephalometric Radiographs at postgraduate teaching hospital
Authors: Khan Anum , Javed Muhammad Qasim , Bilal Rabia , Gaikwad Rahul N 
Published: September 2020

Objective: The objective of our audit was to assess the quality of lateral cephalometric radiographs by investigating the percentage of lateral cephalometric radiographic images that satisfied the good quality standards.
Methods: The standard-based retrospective audit was conducted at Riphah International University, Pakistan, from April to September 2018. The sample size was 50 radiographs that were randomly selected from the radiographs taken over one year. The radiographs were graded according to the standards set by the National Radiation Protection Board by two evaluators after the necessary calibration. Moreover, the percentages of images that met the criteria set by the Royal College of Surgeons of England were identified. The data analysis was carried out by the SPSS software version 23.
Results: Out of the 50 radiographs, thirty-one were Grade-I, sixteen were Grade-II and three radiographs were Grade-III. Furthermore, out of the criteria set by Royal College, one criterion met the 100% standard that was correct head positioning. Less frequent errors were comprised of poor visibility of soft tissue structures (16%), teeth not properly occluded (14%), Incorrect positioning of labels (12%), Sella and Nasion not visible (8%). According to the results of the quality assurance audit, the radiographs fell short of the required standards.
Conclusion: Quality assurance by periodic auditing is important to yield radiographs with maximum diagnostic value, minimal errors, and avoid unnecessary radiation exposure by repeat radiographs. Recommendations were made for the formulation and implementation of comprehensive radiation protection regulations, at all the Dental institutes of Pakistan.
doi: https://doi.org/10.12669/pjms.36.7.2796
How to cite this:Khan A, Javed MQ, Bilal R, Gaikwad RN. Retrospective quality assurance audit of Lateral Cephalometric Radiographs at postgraduate teaching hospital. Pak J Med Sci. 2020;36(7):1601-1606. doi: https://doi.org/10.12669/pjms.36.7.2796
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Die Möllersche Handschrift. Ein unbekanntes Gegenstück zum Andreas-Bach-Buche.
Authors: Wolffheim Werner 
Published: September 2020

Anhang: Notenanhang zu: Werner Wolffheim: Die Möllersche Handschrift. Ein unbekanntes Gegenstück zum Andreas-Bach-Buche. BJ 1912, o.S.
Darauf bezugnehmend: Alfred Dürr: Neues über die Möllersche Handschrift. BJ 1954, S. 75-79
Johann Sebastian Bachs Sammlung von Kantaten seines Vetters Johann Ludwig Bach. Ihre Geschichte und ihr Einfluß auf J. S. Bachs eigene Werke (Schluß)
Authors: Scheide William H. 
Published: September 2020

Bezugnehmend auf: William H. Scheide: Johann Sebastian Bachs Sammlung von Kantaten seines Vetters Johann Ludwig Bach. BJ 1959, S. 52-94
William H. Scheide: Johann Sebastian Bachs Sammlung von Kantaten seines Vetters Johann Ludwig Bach (II. Teil). BJ 1961, S. 5-24
Über Ausmaß und Wesen des Bachschen Parodieverfahrens
Authors: Neumann Werner 
Published: September 2020

Erwähnte Artikel: Arnold Schering: Über Bachs Parodieverfahren. BJ 1921, S. 49-95
Arnold Schering: Kleine Bachstudien. BJ 1933, S. 30-70
Friedrich Smend: Bachs Markus-Passion. BJ 1940-48, S. 1-35
Alfred Dürr: Gedanken zu J. S. Bachs Umarbeitungen eigener Werke. BJ 1956, S. 93-104
Werner Neumann: Eine verschollene Ratswechselkantate J. S. Bachs. BJ 1961, S. 52-57
J. S. Bach - Orgelsachverständiger unter dem Einfluß Andreas Werckmeisters?
Authors: Williams Peter 
Published: September 2020

Werckmeisters Orgel-Probe von 1698 ist das einzige Werk seiner Zeit, das einen Gesamtüberblick über den Orgelbau sowie Anweisungen zur Prüfung von Orgeln bietet. Bachs Zeugnisse von Orgelinspektionen entsprechen in allen wesentlichen Punkten den von Werckmeister genannten Prinzipien; in mehreren Fällen zitieren sie ihn sogar wörtlich. (Übertragung des englischen Resümees am Ende des Bandes)

Darauf bezugnehmend: Peter Williams: Noch einmal: J. S. Bach - Orgelsachverständiger unter dem Einfluß Andreas Werckmeisters? BJ 1986, S. 123-125
Bachs Stellung in der Leipziger Kulturpolitik seiner Zeit (Fortsetzung)
Authors: Siegele Ulrich 
Published: September 2020

Der Teil des Leipziger Rates, der einen Thomaskantor vom Typ "Capellmeister" wählte, nominierte 1722-23 zwei Kandidatengruppen: diejenigen, die hauptsächlich Opern komponierten, und diejenigen, die mit der Orgel verbunden waren. Zur zweiten Gruppe gehörte Bach. Seine Erhebung in die Position des Kantors brachte eine Ausnahmesituation mit sich und führte bereits 1730 zu lauten Einwänden, endete aber erst mit Bachs Tod 1750. (Übertragung des englischen Resümees am Ende des Bandes)

Bezugnehmend auf: Ulrich Siegele: Bachs Stellung in der Leipziger Kulturpolitik seiner Zeit. BJ 1983, S. 7-50
Darauf bezugnehmend: Ulrich Siegele: Bachs Stellung in der Leipziger Kulturpolitik seiner Zeit (Schluß). BJ 1986, S. 33-67
Bachs Stellung in der Leipziger Kulturpolitik seiner Zeit (Schluß)
Authors: Siegele Ulrich 
Published: September 2020

Der dritte Teil dieser Studie untersucht, inwieweit die kulturpolitischen Bedingungen Leipzigs die Pflichten und Tätigkeiten Bachs bestimmt oder beeinflusst haben. Eine Untersuchung, die sich insbesondere auf das System der öffentlichen Verwaltung der Stadt und die Struktur ihrer Kirchenmusik konzentriert, zeigt, dass große Konflikte ausschließlich auf die damals geltenden strukturellen Voraussetzungen zurückzuführen sind. Sowohl die Unterstützung als auch die Opposition, die Bach in Leipzig erhielt, waren im Wesentlichen vorgegeben. (Übertragung des englischen Resümees am Ende des Bandes)

Vorangehende Teile: Ulrich Siegele: Bachs Stellung in der Leipziger Kulturpolitik seiner Zeit. BJ 1983, S. 7-50
Ulrich Siegele: Bachs Stellung in der Leipziger Kulturpolitik seiner Zeit (Fortsetzung). BJ 1984, S. 7-43
Die Herkunft von Bachs "Thema Legrenzianum"
Authors: Hill Robert 
Published: September 2020

Vergleiche auch: Werner Breig: Das "Thema Legrenzianum elaboratum per Joan. Seb. Bach" und die Frühgeschichte der Doppelfuge. BJ 2001, S. 141-150
Rodolfo Zitellini: Das "Thema Legrenzianum" der Fuge BWV 574 - eine Fehlzuschreibung? BJ 2013, S. 243-259
Johann Sebastian Bachs Oboenkonzerte
Authors: Haynes Bruce 
Published: September 2020

Der Artikel bemüht sich angesichts des Missverhältnisses zwischen Bachs offensichtlicher Vorliebe für die Oboe in seinen Vokalwerken und dem Fehlen von Kammermusik für das Instrument darum, mögliche verlorengegangene Urbilder von Oboenwerken aus Übertragungen zu rekonstruieren. Bachs nachweisliche Freiheit, eigene wie fremde Werke für andere Besetzungen zu bearbeiten dient hier als Anknüpfungspunkt, die Möglichkeit von Rückübertragungen zu prüfen. Dazu werden zuerst Indizien für deren (ehemaliges) Vorhandensein zusammengetragen und anschließend anhand eines engen Kriterienkataloges, bei dem besonders die Spielbarkeit (Tonart, Umfang, Lage) der Soloparts für Oboe im Zentrum steht, versucht, diese zu ermitteln. Eingehend geprüft werden BWV 12/1, 99/1, BWV 115/1, BWV 125/1, BWV 156/1, BWV 249a/2, BWV 1053, BWV 1055, BWV 1056, BWV 1059, BWV 1060 und BWV 1063, wobei abschließend für vierzehn Einzelsätze die Möglichkeit konstatiert wird, es könne sich im Original um Stücke für Oboe gehandelt haben. Der Autor kompiliert abschließend vier Oboenkonzerte aus zwölf dieser Sätze.

Erwähnte Artikel: Werner Neumann: Das "Bachische Collegium Musicum". BJ 1960. S. 5-27
Joshua Rifkin: Ein langsamer Konzertsatz Johann Sebastian Bachs. BJ 1978, S. 140-147
Bachs Potsdam-Besuch in den "Franckfurter Gazetten"
Authors: Scior Heinz 
Published: September 2020

Der gesuchte Bericht ist in den untersuchten Zeitungen nicht enthalten.

Vergleiche auch: Markus Rathey: Bachs Besuch in Potsdam und dessen Rezeption in der Münchner Presse. BJ 2011, S. 269-272
Das Trio A-Dur BWV 1025: Eine Lautensonate von Silvius Leopold Weiss, bearbeitet von Johann Sebastian Bach
Authors: Wolff Christoph 
Published: September 2020

Das Trio A-Dur für obligates Cembalo und Violine (BWV 1025) zählt seit langem zu den unechten Werken Bachs, obgleich es in zwei handschriftlichen Quellen unter dem Namen J.S.Bachs überliefert wurde. Neben allgemeinen Bemerkungen zu Echtheitsfragen Bachscher Werke, werden Überlieferungssituation, satztechnische Aspekte sowie Fragen der Autorschaft und der kompositorischen Qualität des Trios A-Dur erörtert. (Karola Weil, Quelle: Bibliographie des Musikschrifttums online)
Darauf bezugnehmend: Karl-Ernst Schröder, Zum Trio A-Dur BWV 1025 (BJ 1995, S. 47-60)
Mehr zur Chronologie von Bachs Weimarer Kantaten
Authors: Melamed Daniel R. 
Published: September 2020

Der Beitrag bringt in die Diskussion um die Chronololgie von J. S. Bachs Weimarer Kantaten ein neues Archivdokument aus Halle/Saale ein, das der Autor vorstellt und auf mögliche Implikationen zu Bachs Weimarer Kantatenschaffen hin untersucht.
Vergleiche auch: Andreas Glöckner: Zur Chronologie der Weimarer Kantaten Johann Sebastian Bachs. BJ 1985, S. 159-164)
Alfred Dürr: Merkwürdiges in den Quellen zu Weimarer Kantaten Johann Sebastian Bachs. BJ 1987, S. 151-157
Klaus Hofmann: Neue Überlegungen zu Bachs Weimarer Kantaten-Kalender. BJ 1993, S. 9-29