bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factor affecting competitive advantage of real estate developers in Indonesia
Authors: Sukaatmadja I Putu Gede 
Published: October 2020

Purpose
This study aims to test and explain the implementation of the green marketing mix (GMM) strategy, based on an environmental orientation (EO) in increasing the competitive advantage (CA) of the real estate developers or companies in Indonesia.

Design/methodology/approach
This study was conducted at real estate developer companies in several cities in Bali, i.e. Denpasar, Gianyar, Buleleng, Singaraja and Tabanan of Bali Province, Indonesia, registered as a member of Real Estate Indonesia. Bali was chosen as a province with a very rapid growth of the property sector than other provinces in Indonesia. This study is about census research. The sample unit is a real estate developer in Bali whose scope of operation project is at least 20 hectares, which means the scale of the property business is middle-class and upper-class companies. The unit of analysis was developer companies in Bali, whereas the respondents were the General Manager, CEO or owners of the company. The respondents were chosen so that each question in the questionnaire could be filled correctly and accurately.

Findings
EO has a positive but insignificant effect on CA. On the other hand, EO has a positive and significant influence on the GMM strategy. Furthermore, the results show that the GMM strategy has a positive and significant effect on CA.

Originality/value
The originality of this study is evident from the effort to deepen the analysis and the results of the hypothesis testing of previous studies; hence, this study uses a GMM strategy for real estate developers as a service company. The mapping of the previous research is done uses variables related to current research. This study seeks to develop a model from some previous studies aimed at enriching the results of research for further development.
A social capital view of women on boards and their impact on firm performance
Authors: Oldford Erin , Ullah Saif , Hossain Ashrafee Tanvir 
Published: October 2020

PurposeThe objective of this paper is to leverage a two-sided view of social capital to develop a model of board gender diversity and firm performance using social capital data from Northeast Regional Center of Rural Development.Design/methodology/approachThe authors examine a large sample of 2,322 US publicly listed firms over the period 1996 to 2009. The final sample consists of 14,634 firm-year observations.FindingsThe authors find that when a firm's social network is not supportive of gender diversity, corporate boards have lower levels of female representation. The strength of a social network's social ties exacerbates the relationship between social capital and board gender diversity. The authors also report a negative relationship between female board membership and firm performance in social networks that are not pro-diversity. Robustness tests reveal that the authors’ social capital view of board diversity also applies to board ethnic diversity.Research limitations/implicationsThis study focuses primarily on blue chip firms due to data constraints. It will be interesting for future researchers to investigate a broader spectrum of firms from a broader perspective of diversity beyond the study’s gender and ethnicity findings. Furthermore, this study assesses the US context, and future research could investigate firm sociability in other national contexts.Practical implicationsThis study contributes new insights to the discourse on gender diversity on corporate boards which stand to inform both policy and practice. The results of the study can inform the position of an industry association on board gender diversity, with guidance on how messaging across networks can be more effective should it account for the hidden bias that the authors uncover in the current study. From a manager's perspective, this study can help those managers and boards trying to enhance board gender diversity by providing a more complete understanding of the factors that can limit progress.Originality/valueThis study contributes a social capital view of board gender diversity to the growing literature of corporate governance, board diversity and local environmental influences on corporate policies.
Irreversibility analysis in squeezing nanofluid flow with thermal radiation
Authors: Hayat T. , Ahmad M. Waqar , Khan Sohail Ahamd , Alsaedi Ahmed 
Published: October 2020

PurposeMagnetohydrodynamic (MHD) nanoliquid are significant for thermal conductivity enhancement. The examination of heat transfer of crushing time-subordinate liquid flow past isometric surfaces has throughout the decades been a field of consideration for its wide scope of physical necessities: nourishment preparation, pressure, grease setup and hydrodynamic machines. Entropy generation in the squeezing flow of viscous nanomaterial is developed. MHD, Brownian motion and thermophoresis are considered. Porous space between the disks is taken. The analysis is carried out in the presence of radiation and viscous dissipation.Design/methodology/approachNonlinear systems are reduced to an ordinary one through similarity variables. The convergent solution is developed by employing the homotopy analysis technique (HAM).FindingsConvergent homotopic solutions are developed for the velocity, temperature and concentration. Entropy generation and Bejan number are explained. Skin friction and Nusselt number and Sherwood number are analyzed. For a higher approximation of porosity, parameter velocity is augmented. Temperature upsurges for larger thermophoresis and Brownian diffusion parameters. Concentration has an increasing effect on thermophoresis and Brownian diffusion parameters. For the rising value of the radiation parameter, both the Bejan number and entropy rate have increasing behaviors.Originality/valueNo such work is yet published in the literature.
Trying to motivate employees through intimidation? Think again
Authors: Meisler Galit 
Published: October 2020

PurposeThis study advances our knowledge about counternormative emotion management processes utilized in organizations. We investigate a research model in which managerial intimidation, and more specifically subordinates' perceptions about it, evokes fear, which reduces their job satisfaction and increases their turnover intentions.Design/methodology/approachThe model was tested using two samples, one from the public sector and the other from the private sector. The data were collected in three waves using questionnaires.FindingsOur findings validated the research model in the public sector alone, revealing sectorial differences regarding the destructive emotional and attitudinal implications of perceived managerial intimidation.Originality/valueThe current study sheds light on counternormative emotion management processes utilized in organizations, a topic we know little about. Furthermore, it advances our knowledge regarding the responses of the targets of impression management attempts, revealing sectorial differences about them. Finally, this study broadens our understanding about intimidation, an under-investigated impression management strategy.
Safety and effectiveness of secukinumab in psoriasis vulgaris and psoriatic arthritis: Real‐world evidence in Japan
Authors: Fujita Hideki , Ohtsuki Mamitaro , Morita Akimichi , Nagao Ryuji , Seko Noriko , Matsumoto Kazuko , Tani Yumiko , Terui Tadashi 
Published: October 2020

AbstractSecukinumab, a fully human monoclonal antibody that selectively neutralizes interleukin‐17A, has been available for the treatment of moderate to severe psoriasis and psoriatic arthritis since February 2015 in Japan. Because there was a time gap after the previous approval of biologics for psoriatic disease indication, it was suggested that patients to be treated with secukinumab at its launch might have refractory disease symptoms. In order to assess the safety and effectiveness of secukinumab in those patients, a 52‐week, open‐label, multicenter, observational cohort study was conducted. In total, 306 and 250 patients were included in the safety and effectiveness analysis sets, respectively. Over half of patients had previously received biologics (56.9%). Adverse events, serious adverse events and adverse reactions were reported in 41.2%, 7.2% and 24.2% of patients, respectively. The most commonly reported adverse reactions were oral candidiasis (2.9%), consistent with those reported in clinical studies. In addition, none of the patient characteristics assessed for the effect on safety of secukinumab increased the occurrence of adverse reactions. Psoriasis Area and Severity Index score (mean ± standard deviation) improved from baseline (14.7 ± 12.3) to week 12 (1.78 ± 3.3), which was maintained up to week 24 (1.59 ± 3.0). The proportion of patients with a Dermatology Life Quality Index score of 0/1 improved from baseline (2.2%) to week 12 (64.7%) and sustained up to week 24 (71.4%). In addition to the skin symptoms, improvement was observed in all psoriatic arthritis disease‐related assessments. The current study reaffirmed the safety and effectiveness of secukinumab with broader patients than those in the clinical studies.
Detection rates of periodontal bacteria and herpesviruses in different forms of periodontal disease
Authors: Puletic Miljan , Popovic Branka , Jankovic Sasa , Brajovic Gavrilo 
Published: October 2020

AbstractThe aim was to investigate the detection rates of periodontal bacteria (Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, and Aggregatibacter actinomycetemcomitans) and herpesviruses (herpes simplex virus‐1 [HSV‐1], cytomegalovirus [CMV], and Epstein‐Barr virus [EBV]) in different forms and severity of periodontal disease, and to compare them with those in periodontally healthy subjects. One hundred and twenty‐nine patients participated in the study: 39 diagnosed with periodontal abscess (PA), 33 with necrotizing ulcerative periodontitis (NUP), 27 with chronic periodontitis (CP), and 30 participants with healthy periodontal tissue represented a healthy control group. All patients with periodontal disease (PA, NUP, and CP) were also divided into two groups according to the severity of their disease: moderate and severe periodontitis. The subgingival samples were collected from the periodontitis active sites and the detection of microorganisms was performed by end‐point polymerase chain reaction analyses. The results revealed significantly higher detection rates of P. gingivalis, T. forsythia, and P. intermedia in all three groups of patients with periodontitis than in healthy participants. The highest detection rate of A. actinomycetemcomitans was noticed in CP, which was significantly higher than that in PA, NUP, and healthy control. The occurrence of EBV was significantly higher in NUP than in CP and healthy participants. CMV was detected significantly more frequently in PA and NUP than in CP and healthy participants. Comparisons among healthy participants and patients with moderate and severe periodontitis showed significantly higher detection rates of EBV and CMV in patients with severe forms of periodontitis than in healthy participants and those with moderate periodontitis.
Phenological synchronization of seasonal bird migration with vegetation greenness across dietary guilds
Authors: La Sorte Frank A. , Graham Catherine H. 
Published: October 2020

Abstract

The seasonal movement of animals has been linked to seasonal variation in ecological productivity, and it has been hypothesized that primary consumers synchronize migration with vegetation phenology. Within temperate regions of the Northern Hemisphere, herbivorous bird species often track the phenology of vegetation greenness during spring migration. Phenological synchronization with vegetation greenness by migratory birds in other dietary guilds, across the full extent of their annual distributions during both spring and autumn migration, has not been explored.

Here, we document population‐level associations with a remotely sensed measure of vegetation greenness for 230 North American migratory bird species in seven dietary guilds across the full annual cycle using eBird occurrence information for the combined period 2006–2018.

Evidence of phenological synchronization was strongest for omnivores, herbivores, herbivore–granivores and granivores during spring and autumn migration, except for omnivores in the west during spring migration. Strong evidence of synchronization was also observed for insectivores during spring migration and carnivores during spring and autumn migration that migrated across the entire breadth of the continent. The level of evidence declined for insectivores in the west and east during spring migration, and for nectarivores in the west during spring and autumn migration. Limited evidence was also found for insectivores in the east during autumn migration, insectivores in the west and the centre of the continent during spring and autumn migration, and carnivores in the west during spring migration. Carnivores in the west during autumn migration showed the weakest evidence of synchronization.

We found broad support across an array of dietary guilds for phenological coupling between vegetation greenness and seasonal bird migration within North America. Our results highlight the potential for many migratory bird species to encounter phenological mismatches as vegetation phenology responds to climate change. Our findings emphasize the need to better understand the environmental cues that regulate migratory behaviour across dietary guilds, consumer levels and migration tactics.
Serum exosomal miR‐1269a serves as a diagnostic marker and plays an oncogenic role in non‐small cell lung cancer
Authors: Wang Xue , Jiang Xinquan , Li Juan , Wang Jingzheng , Binang Helen , Shi Shuang , Duan Weili , Zhao Yinghui , Zhang Yi 
Published: October 2020

BackgroundEarly diagnosis improves the prognosis for non‐small cell lung cancer (NSCLC); therefore, there is a pressing need for effective diagnostic methods for NSCLC. Increasing evidence indicates that serum exosomal micro RNAs (miRNAs) represent promising diagnostic and prognostic markers for multiple cancers. Here, we explored a panel of miRNAs for NSCLC diagnosis and functionally characterized miR‐1269a in the pathogenesis of NSCLC.Methods: First, we analyzed high‐throughput data from The Cancer Genome Atlas (TCGA) to identify differentially expressed miRNAs between NSCLC patients and healthy controls. We examined the expression profiles of the identified miRNAs using qRT‐PCR.Results: We found that four micro‐RNAs (hsa‐miR‐9‐3p, hsa‐miR‐205‐5p, hsa‐miR‐210‐5p, and hsa‐miR‐1269a) were more abundant in serum exosomes from NSCLC patients. A logistic regression model validated the diagnostic efficacy of the four‐microRNA panel, allowing us to distinguish NSCLC patients from healthy controls with AUCs of 0.915 and 0.878 for the training and validation sets, respectively. Functionally, NSCLC cell proliferation, migration, and invasion were affected by the aberrant expression of hsa‐miR‐1269a in culture. Reduced expression of miR‐1269a resulted in reduced proliferation, migration, and invasion through targeting the forkhead box O1 gene (FOXO1).Conclusions: Taken together, our study identified a panel of four serum exosomal miRNAs as a potential noninvasive diagnostic biomarker for NSCLC. The interactions between FOXO1 and miR‐1269a represent novel potential targets for NSCLC therapy.
A regional evaluation of the health care utilization and outcomes of children and young people with long‐term ventilation needs
Authors: Popejoy Emma , Marufu Takawira C. , Thomas David A. , Gregory Rachel , Frost Adele , McNarry Nicola , Hurley Matthew , Bean Dorothy , Manning Joseph C. 
Published: October 2020

AbstractBackgroundGlobally, the number of children and young people (CYP) with long‐term ventilation (LTV) needs is increasing, with high associated health care costs, due to frequent hospital admissions and contact with community health care services. However, demographic, health care utilization and outcome details of the CYP cared for locally is unknown. This study aimed to examine health care utilization and outcomes for this patient population.MethodsRoutinely collected data from 2014 to 2018 were extracted from local LTV team records and from hospital electronic patient records. Descriptive and inferential statistical analysis was performed using SPSS 17.ResultsA total of 112 CYP aged 0–17 years old were included in the evaluation.Sixty per cent (n = 67) commenced ventilation in hospital, and 62% (n = 69) had at‐least one hospitalization event whilst they were on LTV, with a median length of stay of 3 days. Most hospitalizations were unplanned and respiratory in nature. Ninety‐five per cent (n = 106) of CYP accessed at least one clinic appointment whilst on LTV, with a median of 20 outpatient clinic appointments during the study period. The majority of CYP received time‐intensive support from LTV nurses and physiotherapists during the period that they received LTV. Minimal seasonal variation existed in relation to hospital admissions. Year on year increasing trend of hospital admissions was noted. The observed mortality rate was 3.6% (n = 4), 72.3% (n = 81) remained active on LTV, 14% (n = 16) were liberated from their ventilation and 9% (n = 10) transitioned to adult care by the end of the study.ConclusionThe study highlights the most common modes of health care utilization for CYP with LTV needs. To enable formalization of future resource planning and accurate assessment of health care utilization in evaluations, there is an urgent need to create a systematic approach for relevant LTV data collection.
Biological variation and analytical goals of four thyroid function biomarkers in healthy European volunteers
Authors: Mairesse Antoine , Wauthier Loris , Courcelles Louisiane , Luyten Urszula , Burlacu Maria‐Cristina , Maisin Diane , Favresse Julien , van Dievoet Marie‐Astrid , Gruson Damien 
Published: October 2020

AbstractBackgroundInterpretation of thyroid function tests by means of biological variation (BV) data is essential to identify significant changes between serial measurements at an individual level. Data on thyroid parameters in adults are limited.ObjectivesWe aimed at determining the BV of four thyroid function test (thyroid‐stimulating hormone (TSH), free thyroxin (FT4), free triiodothyronine (FT3) and thyroglobulin (Tg)) by applying recent recommendations to acquire BV data on a latest generation of immunoassay.MethodsNineteen healthy volunteers (8 males and 11 females) were drawn every week during 5 consecutive weeks. Samples were analysed in duplicate on the Cobas 602 analyzer (Roche Diagnostics). After normality assessment, outlier exclusion and homogeneity of variance analysis, analytical variation (CVA), within‐subject biological variation (CVI) and between‐subject biological variation (CVG) were determined using nested ANOVA.ResultsCVA, CVI and CVG were 0.9%, 19.7% and 37.6% for TSH; 3.6%, 4.6% and 10.8% for FT4; 2.2%, 6.0% and 8.6% for FT3; and 0.9%, 15.4% and 84.9% for Tg. Index of individuality (II) for all parameters was between 0.2 and 0.7. The percentage above which the change between two measures is truly significant (reference change value) was 54.7% for TSH, 16.2% for FT4, 17.7% for FT3 and 42.8% for Tg.ConclusionBased on recent international recommendations, our study provides updated BV data for four thyroid function tests in European healthy volunteers. Reliable BV characteristics, and especially RCV, can facilitate the interpretation of consecutive thyroid function tests in an individual and therefore have the potential to efficiently support clinical decisions regarding thyroid diseases.
Young people looking forward: Imagined future and normative tensions in urban Norway
Authors: Andersen Nina H. B. , Gubrium Erika , Ulvik Oddbjørg S. 
Published: October 2020

AbstractWe explore the meaning‐making practices of ‘little personal stories’ and ‘big societal stories’ in the imagined futures of 12‐ and 13‐year‐olds within Norway, known for its egalitarian ideals and welfare society. Using the concept ‘prospective narratives’, we explore these practices through the students' narrative world‐making. The narratives connect the imagined future with gender and class variations related to larger social norms in the arenas of work and family. They demonstrate embodied and positioned cultural knowledge of the present, reflecting tensions between dominant social norms—‘big stories’—in terms of child‐centred parenting, active work‐life and egalitarian ideals across gender and class.
Working landscapes need at least 20% native habitat
Authors: Garibaldi Lucas A. , Oddi Facundo J. , Miguez Fernando E. , Bartomeus Ignasi , Orr Michael C. , Jobbágy Esteban G. , Kremen Claire , Schulte Lisa A. , Hughes Alice C. , Bagnato Camilo , Abramson Guillermo , Bridgewater Peter , Carella Dulce Gomez , Díaz Sandra , Dicks Lynn V. , Ellis Erle C. , Goldenberg Matías , Huaylla Claudia A. , Kuperman Marcelo , Locke Harvey , Mehrabi Zia , Santibañez Fernanda , Zhu Chao‐Dong 
Published: October 2020

AbstractInternational agreements aim to conserve 17% of Earth's land area by 2020 but include no area‐based conservation targets within the working landscapes that support human needs through farming, ranching, and forestry. Through a review of country‐level legislation, we found that just 38% of countries have minimum area requirements for conserving native habitats within working landscapes. We argue for increasing native habitats to at least 20% of working landscape area where it is below this minimum. Such target has benefits for food security, nature's contributions to people, and the connectivity and effectiveness of protected area networks in biomes in which protected areas are underrepresented. We also argue for maintaining native habitat at higher levels where it currently exceeds the 20% minimum, and performed a literature review that shows that even more than 50% native habitat restoration is needed in particular landscapes. The post‐2020 Global Biodiversity Framework is an opportune moment to include a minimum habitat restoration target for working landscapes that contributes to, but does not compete with, initiatives for expanding protected areas, the UN Decade on Ecosystem Restoration (2021–2030) and the UN Sustainable Development Goals.
Reduction of Renal Preservation/Reperfusion Injury by Controlled Hyperthermia During Ex Vivo Machine Perfusion
Authors: Minor Thomas , von Horn Charlotte 
Published: October 2020

The possible reno‐protective effect of a controlled brief heat‐shock treatment during isolated ex vivo machine perfusion of donor grafts prior to reperfusion should be investigated in a primary in vitro study. Porcine kidneys (n = 14) were retrieved after 20 minutes of cardiac standstill of the donor and subjected to 20 hours of static cold storage in University of Wisconsin solution. Prior to reperfusion, kidneys were subjected to 2 hours of reconditioning machine perfusion with gradual increase in perfusion temperature up to 35°C. In half of the kidneys (n = 7), a brief hyperthermic impulse (10 minutes perfusion at 42°C) was implemented in the machine perfusion period. Functional recovery of the grafts was observed upon normothermic reperfusion in vitro. Hyperthermic treatment resulted in a 50% increase of heat shock protein (HSP) 70 and HSP 27 mRNA and was accompanied by ~ 50% improvement of tubular re‐absorption of sodium and glucose upon reperfusion, compared with the controls. Furthermore, renal loss of aspartate aminotransferase was significantly reduced to one‐third of the controls as was urinary protein loss, evaluated by the albumin to creatinine ratio. It is concluded that ex vivo heat‐shock treatment seems to be an easily implementable and promising option to enhance renal self‐defense machinery against reperfusion injury after preservation that merits further investigation in preclinical models.