bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parafoveal pre-processing in children reading English: The importance of external letters
Authors: Milledge Sara V. , Blythe Hazel I. , Liversedge Simon P. 
Published: September 2020

AbstractAlthough previous research has demonstrated that for adults external letters of words are more important than internal letters for lexical processing during reading, no comparable research has been conducted with children. This experiment explored, using the boundary paradigm during silent sentence reading, whether parafoveal pre-processing in English is more affected by the manipulation of external letters or internal letters, and whether this differs between skilled adult and beginner child readers. Six previews were generated: identity (e.g., monkey); external letter manipulations where either the beginning three letters of the word were substituted (e.g., rackey) or the last three letters of the word were substituted (e.g., monhig); internal letter manipulations; e.g., machey, mochiy); and an unrelated control condition (e.g., rachig). Results indicate that both adults and children undertook pre-processing of words in their entirety in the parafovea, and that the manipulation of external letters in preview was more harmful to participants’ parafoveal pre-processing than internal letters. The data also suggest developmental change in the time course of pre-processing, with children’s pre-processing delayed compared to that of adults. These results not only provide further evidence for the importance of external letters to parafoveal processing and lexical identification for adults, but also demonstrate that such findings can be extended to children.
Small Dense Low-Density Lipoprotein as Risk Factor for Atherosclerosis in Type 2 Diabetes Mellitus
Authors: Rashid Haji Muhammad , Hassan Hiza , Khan Mudassar , Khan Jamal , Khan Hasanat 
Published: September 2020

Background: Dyslipidemia is a common complication of diabetes and a major risk factor for atherosclerosis. Small dense low-density lipoprotein cholesterol (sdLDL-C) is a sub class of low-density lipoprotein cholesterol. sdLDL-C is highly atherogenic and it has been wildly studied in diabetic dyslipidemia.
Objectives: The study was carried out to explore the hidden risk of atherosclerosis due to variation of sdLDL-C in Type 2 diabetic patients, whose lipid profiles were normal.
Methodology: We enrolled 126 T2DM patients and 126 age and sex matched normal controls in this study. Fasting lipid levels in normal range was the selection criteria for both groups. Hemoglobin A1c (HbA1c), SdLDL-C, Triglycerides (TG), Total-Cholesterol, Low-Density Lipoprotein (LDL) and High-Density Lipoprotein (HDL) were performed for both groups. Results were compared by two samples t-tests.
Results: SdLDL-C levels (54.6 ± 10.2) in T2DM were significantly higher than control group (41.6 ± 8.4) with p value <0.00001. There was strong positive correlation (r2 = 0.591) between HbA1c and sdLDL-C of T2DM patients.
Conclusion: T2DM patients even with normal lipids profile are at risk of atherosclerosis due to high level of atherogenic sdLDL-C.
H0 Reconstruction with Type Ia Supernovae, Baryon Acoustic Oscillation and Gravitational Lensing Time Delay
Authors: Lyu Meng-Zhen , Haridasu Balakrishna S. , Viel Matteo , Xia Jun-Qing 
Published: September 2020

Abstract
There is a persistent H
0-tension, now at more than ≳4σ level, between the local distance ladder value and the Planck cosmic microwave background measurement, in the context of flat Lambda-cold-dark-matter (ΛCDM) model. We reconstruct H(z) in a cosmological-model-independent way using three low-redshift distance probes including the latest data from baryon acoustic oscillation, supernova Ia (SN Ia) and gravitational lensing time-delay (GLTD) observations. We adopt general parametric models of H(z) and assume a Gaussian sound horizon at drag epoch,

, from Planck measurement. The reconstructed Hubble constant H
0,rec using Pantheon SN Ia and Baryon Acoustic Oscillations (BAO) data are consistent with the Planck flat ΛCDM value. When including the GLTD data, H
0,rec increases mildly, yet remains discrepant with the local measurement at ∼2.2σ level. With our reconstructions being blind to the dark sectors at low redshift, we reaffirm the earlier claims that the Hubble tension is not likely to be solved by modifying the energy budget of the low-redshift universe. We further forecast the constraining ability of future realistic mock BAO data from Dark Energy Spectroscopic Instrument and GLTD data from Large Synoptic Survey Telescope, combining which, we anticipate that the uncertainty of H
0,rec would be improved by ∼27%, reaching

uncertainty level.
The Timing Behavior of the Central Compact Object Pulsar 1E 1207.4−5209
Authors: Gotthelf E. V. , Halpern J. P. 
Published: September 2020

Abstract
We present 20 yr of timing observations for 1E 1207.4−5209, the central compact object in supernova remnant PKS 1209−51/52, to follow up on our detection of an unexpected timing glitch in its spin-down. Using new XMM-Newton and NICER observations of 1E 1207.4−5209, we now find that the phase ephemeris can be well modeled by either two small glitches, or extreme timing noise. The implied magnitudes of the frequency glitches are

and

, at epochs 2010.9 and 2014.4, respectively. The updated timing solutions also rule out our previous suggestion of a large glitch in the frequency derivative

. No other canonical pulsar with such a small spin-down rate (

Hz s−1) or surface dipole magnetic field strength (

G) has been observed to glitch; the glitch activity parameter of 1E 1207.4−5209 is larger than that of more energetic pulsars. Alternative parameterizations that do not involve glitches can fit the data, but they have timing residuals or a second frequency derivative

that are orders of magnitude larger than in pulsars with similar spin-down parameters. These timing properties of 1E 1207.4−5209 further motivate the leading theory of central compact objects, that an initial B-field of normal strength was buried in the neutron star crust by fallback of supernova ejecta, suppressing the surface dipole field. The slow reemergence of the buried field may be involved in triggering glitches or excess timing noise.
A 3D Framework to Explore the Propagation Effects in Stars Exhibiting Electron Cyclotron Maser Emission
Authors: Das Barnali , Mondal Surajit , Chandra Poonam 
Published: September 2020

Abstract
Recently, coherent radio emission has been discovered from a number of hot magnetic stars, via the process of electron cyclotron maser emission (ECME). This emission, observed in the form of highly circularly polarized pulses, has interesting properties that contain information about the host star. One of the important properties of ECME is the frequency dependence of the pulse arrival time. This has been attributed to the propagation effect by Trigilio et al. and could explain the sequence observed for CU Vir qualitatively. However, no quantitative treatment exists for this phenomenon despite it being a promising tool to estimate the density in the stellar magnetosphere. Additionally, the effect of propagation through the magnetosphere on ECME has been thought to be limited to giving rise to a particular sequence of arrival of pulses, and in some cases producing the upper cutoff frequency for ECME. Here, we present a framework to deal with the propagation effect by considering continuous refraction in the inner magnetosphere of the star. This framework is capable of incorporating any type of density distribution, and in principle any type of magnetic field, though we limit ourselves to a dipolar magnetic field for this work. We show by simulation that for stars with high obliquity, the propagation effect can influence not only the sequence of arrival of pulses drastically, but also the pulse shapes, and the observability of a pulse from a particular magnetosphere.
The Blue Compact Dwarf Galaxy VCC 848 Formed by Dwarf–Dwarf Merging: H i Gas, Star Formation, and Numerical Simulations
Authors: Zhang Hong-Xin , Smith Rory , Oh Se-Heon , Paudel Sanjaya , Duc Pierre-Alain , Boselli Alessandro , Côté Patrick , Ferrarese Laura , Gao Yu , Hunter Deidre A. , Puzia Thomas H. , Peng Eric W. , Rong Yu , Shin Jihye , Zhao Yinghe 
Published: September 2020

Abstract
A clear link between a dwarf–dwarf merger event and enhanced star formation (SF) in the recent past was recently identified in the gas-dominated merger remnant VCC 848, offering by far the clearest view of a gas-rich late-stage dwarf–dwarf merger. We present a joint analysis of JVLA H i emission line mapping, optical imaging, and numerical simulations of VCC 848 in order to examine the effect of the merger on the stellar and gaseous distributions. VCC 848 has less than 30% of its H i gas concentrated within the central high-surface-brightness star-forming region, while the remaining H i is entrained in outlying tidal features. Particularly, a well-defined tidal arm reaches N(H i) comparable to the galaxy center but lacks SF. The molecular gas mass inferred from the current SF rate (SFR) dominates over the atomic gas mass in the central ∼1.5 kpc. VCC 848 is consistent with being a main-sequence star-forming galaxy for its current stellar mass and SFR. The H ii region luminosity distribution largely agrees with that of normal dwarf irregulars with similar luminosities, except that the brightest H ii region is extraordinarily luminous. Our N-body/hydrodynamical simulations imply that VCC 848 is a merger between a gas-dominated primary progenitor and a gas-bearing star-dominated secondary. The progenitors had their first passage on a near-radial noncoplanar orbit more than 1 Gyr ago. The merger did not build up a core as compact as typical compact dwarfs with a centralized starburst, which may be partly ascribed to the star-dominated nature of the secondary and, in a general sense, a negative stellar feedback following intense starbursts triggered at early stages of the merger.
Chandra Observations of Candidate Subparsec Binary Supermassive Black Holes
Authors: Saade M. Lynne , Stern Daniel , Brightman Murray , Haiman Zoltán , Djorgovski S. G. , D’Orazio Daniel , Ford K. E. S. , Graham Matthew J. , Jun Hyunsung D. , Kraft Ralph P. , McKernan Barry , Vikhlinin Alexei , Walton Dominic J. 
Published: September 2020

Abstract
We present analysis of Chandra X-ray observations of seven quasars that were identified as candidate subparsec binary supermassive black hole (SMBH) systems in the Catalina Real-Time Transient Survey based on the apparent periodicity in their optical light curves. Simulations predict that close-separation accreting SMBH binaries will have different X-ray spectra than single accreting SMBHs, including harder or softer X-ray spectra, ripple-like profiles in the Fe K-α line, and distinct peaks in the spectrum due to the separation of the accretion disk into a circumbinary disk and mini disks around each SMBH. We obtained Chandra observations to test these models and assess whether these quasars could contain binary SMBHs. We instead find that the quasar spectra are all well fit by simple absorbed power-law models, with the rest-frame 2–10 keV photon indices, Γ, and the X-ray-to-optical power slopes, α
OX, indistinguishable from those of the larger quasar population. This may indicate that these seven quasars are not truly subparsec binary SMBH systems, or it may simply reflect that our sample size was too small to robustly detect any differences. Alternatively, the X-ray spectral changes might only be evident at energies higher than probed by Chandra. Given the available models and current data, no firm conclusions are drawn. These observations will help motivate and direct further work on theoretical models of binary SMBH systems, such as modeling systems with thinner accretion disks and larger binary separations.
Mass Ratios of Merging Double Neutron Stars as Implied by the Milky Way Population
Authors: Andrews Jeff J. 
Published: September 2020

Abstract
Of the seven known double neutron stars (DNSs) with precisely measure masses in the Milky Way that will merge within a Hubble time, all but one has a mass ratio, q, close to unity. Recently, precise measurements of three post-Keplerian parameters in the DNS J1913+1102 constrain this system to have a significantly non-unity mass ratio of 0.78 ± 0.03. One may be tempted to conclude that approximately one out of seven (14%) DNS mergers detected by gravitational-wave observatories will have mass ratios significantly different from unity. However J1913+1102 has a relatively long lifetime (pulsar characteristic age plus the system’s merger time due to gravitational-wave radiation) of ≈3 Gyr. We show that when system lifetimes and observational biases are taken into account, the population of Galactic DNSs implies that ≃98% of all merging DNSs will have q > 0.9. We then apply two separate fitting formulas informed by 3D hydrodynamic simulations of DNS mergers to our results on Galactic DNS masses, finding that either ≃0.004

or ≃0.009

of material will be ejected at merger, depending on which formula is used. These ejecta masses have implications for both the peak bolometric luminosities of electromagnetic counterparts (which we find to be ∼1041 erg s−1) as well as the r-process enrichment of the Milky Way.
Cosmic Amorphous Dust Model as the Origin of Anomalous Microwave Emission
Authors: Nashimoto Masashi , Hattori Makoto , Poidevin Frédérick , Génova-Santos Ricardo 
Published: September 2020

Abstract
We have shown that the thermal emission of the amorphous dust composed of amorphous silicate dust (a-Si) and amorphous carbon dust (a-C) provides an excellent fit both to the observed intensity and the polarization spectra of molecular clouds. The anomalous microwave emission (AME) originates from the resonance transition of the two-level systems attributed to the a-C with an almost spherical shape. On the other hand, the observed polarized emission in submillimeter wave bands is coming from a-Si. By taking into account a-C, the model prediction of the polarization fraction of the AME is reduced dramatically. Our model prediction of the 3σ lower limits of the polarization fraction of the Perseus and W 43 molecular clouds at 17 GHz are 8.129 × 10−5 and 8.012 × 10−6, respectively. The temperature dependence of the heat capacity of a-C shows the peculiar behavior compared with that of a-Si. So far, the properties of a-C are unique to interstellar dust grains. Therefore, we coin our dust model as the cosmic amorphous dust model.
Eviscerated alive: Novel and macabre feeding strategy in Oligodon fasciolatus (Günther, 1864) eating organs of Duttaphrynus melanostictus (Schneider, 1799) in Thailand
Authors: Bringsøe Henrik , Suthanthangjai Maneerat , Suthanthangjai Winai , Nimnuam Kanjana 
Published: September 2020

A hitherto unknown feeding mode among snakes is described for the colubrid snake Oligodon fasciolatus in Northeast Thailand. Three cases of O. fasciolatus using enlarged posterior maxillary teeth to cut open the abdomen of a live poisonous toad Duttaphrynus melanostictus and eat its organs are described. The snakes and toads fought vigorously, and the toads secreted toxic white liquid on the dorsum and neck. The snakes inserted their heads into the abdomen of the toads, pulled out some of the organs and swallowed them. The snakes and toads were adults. All three cases were documented by extensive photographic material.
In a fourth case from Central Thailand, an adult O. fasciolatus was observed swallowing an entire semi-adult D. melanostictus.
The majority of all snake species swallow their prey in one piece, but to place our observations in a broader context we review a number of exceptions.
Dampening Antigen-Specific T Cell Responses with Antigens Encapsulated in Polyphenolic Microcapsules
Authors: Feduska Joseph M , Kozlovskaya Veronika , Alford Aaron , Padgett Lindsey E , Kharlampieva Eugenia , Tse Hubert M 
Published: September 2020

Abstract
Efficient T cell activation and effector responses require an antigenic peptide presented on the MHC complex to the TCR (signal 1), costimulatory molecule interactions between T cells and APCs (signal 2), and the synthesis of innate immune-derived proinflammatory cytokines and reactive oxygen species (signal 3). We previously demonstrated that the third signal dissipation impairs autoreactive T cell activation. In this study, we tested the hypothesis that encapsulation of Ag with an antioxidant-containing biomaterial would induce Ag-specific hyporesponsiveness. We cocultured bone marrow–derived dendritic cells with microcapsules composed of multilayer-assembled poly(N-vinylpyrrolidone) (PVPON) and the antioxidant tannic acid (TA). LPS-activated dendritic cells cocultured with (PVPON/TA) microcapsules displayed a decrease in TNF-α, IL-12p70, and CXCL10 synthesis. To study Ag-specific T cell responses, we incorporated chicken OVA into the (PVPON/TA) multilayers and stimulated OT-II splenocytes in a primary recall assay. Flow cytometric analysis demonstrated a significant inhibition of CD4 T cell activation markers, upregulation of CTLA-4 and PD-1, and blunted secretion of IL-2, IFN-γ, TNF-α, and CXCL10 by ELISA. To test microcapsule efficacy in vivo, we immunized OT-II mice with (PVPON/TA)-OVA microcapsules and performed an OVA recall assay. Immunization of OT-II mice with (PVPON/TA)-OVA microcapsules elicited a decrease in CD4 T cell differentiation and effector responses including IFN-γ, TNF-α, CCL3, and CCL5 by ELISA compared with OVA immunization alone. These data show that microcapsules composed of antioxidant and encapsulated Ags can effectively blunt innate immune-derived proinflammatory third signal synthesis necessary for Ag-specific effector T cell responses and present a prospective strategy for T cell–mediated autoimmunity.
A Cross-Sectional Survey to Evaluate Acquaintance about Dental Photography among Dental Students in Daily Clinical Practice
Authors: Abouzeid Hoda Lotfy , Chaturvedi Saurabh , Ahmed Alzahrani Fawziah , Alqahtani Naseer M. , Salim AlQarni Abdulhkeem Ali , Alaajam Wafa Hassan , Elsir Elmahdi Asim 
Published: September 2020

Background In today's world of digital dentistry, dental photography plays an important role as multilevel significance and represents the synonym of contemporary dentistry. Thus, we aimed at evaluating the acquaintance of practice, opportunity and morals of dental photography in everyday practice among undergraduate dental students. Design and methods The current research was an observational cross-sectional study. Total 233 students participated; each was given questionnaire consisted of three parts covering the following aspects: questions 1 to 3 on the practice of dental photography, questions 4 to 7 on morals in dental photography and question 8 to 11 on opportunities of dental photography. The answers were tabulated and statistically analysed and association with the factors were tested for significance using Chi-square tests, and P<0.05 was considered statistically significant. Results The total response rate was 86%. Among the 201 respondents, 100 were males and 101 females; 96% male students were taking photographs and 93% females were taking photographs, on regular basis. Phone cameras (41.3%) were the most commonly used device followed by DSLR cameras. Surveyed students mentioned patient education (53.2%) as most needed requirement for taking photographs, followed by treatment planning (49.8%) and monitoring of the treatment outcome (34.3%). Ninety-one percent of students feel that there is an opportunity for advancement in dental photography techniques. Conclusions The participants aware of dental photography, but they require detail insight on proper capturing of photographs and morals, with regards to confidentiality of the patient and patient consent.
Comparison of radioiodine ablation rates between low versus high dose, and according to the surgeon's expertise in the low-risk group of differentiated thyroid cancer
Authors: Norouzi Ghazal , Shafiei Babak , Hadaegh Farzad , Qutbi Mohsen , Asli Isa , Jafari Esmail , Javadi Hamid , Assadi Majid 
Published: September 2020

AbstractRadioiodine ablation following surgery is the accepted treatment for patients with differentiated thyroid cancer (DTC). Since that surgical volume and radioiodine dose can have impact on treatment outcome, we aimed to evaluate them on the treatment outcome of low-risk DTC patients. Low-risk DTC patients were classified into four groups, including (1) thyroidectomy was performed by thyroid surgeon and low-dose (1850 MBq [30 mCi]) radioiodine was administered (n = 17), (2) thyroidectomy was performed by thyroid surgeon and high-dose (3700 MBq [100 mCi]) radioiodine was administered (n = 10), (3) thyroidectomy was performed by general surgeon and low-dose radioiodine was administered (n = 22), and (4) thyroidectomy was performed by general surgeon and high-dose radioiodine was administered (n = 29). All patients were followed at least for 6 months and also for evaluation of treatment success, neck sonography, thyroid-stimulating hormone-off, thyroglobulin (Tg)-off, and anti-Tg-off tests were performed. Furthermore, two common radioiodine treatment-associated side effects, including dry mouth, and nausea/vomiting were assessed for all patients. Seventy-eight low-risk DTC patients (female: 70 [89.7%]; male: 8 [10.3%]) aged from 18 to 78 years old with mean of 41.96 ± 13.42 years were enrolled in this study. In total, the treatment was successful in 96.2% of patients. There was no significant difference in treatment success among groups (P > 0.05), while there was a significant association among administered activity and side effects. In low dose patients, only one patient complained from dry mouth; however, 11/39 patients who received high dose of iodine complained from dry mouth (P = 0.002). In addition, 9/39 high dose patients suffered from vomiting/nausea, while none of low-dose patients suffered from vomiting/nausea (P = 0.001). In low-risk DTC patients, surgical volume and amounts of radioiodine had no significant impact on treatment results; therefore, low dose radioiodine following thyroidectomy may be preferable to low-risk DTC patients to avoid side effects.
Role of 18F-FDG positron emission tomography in carotid atherosclerotic plaque imaging: A systematic review
Authors: Ravikanth Reddy 
Published: September 2020

AbstractStroke and other thromboembolic events in the brain are often due to carotid artery atherosclerosis, and atherosclerotic plaques with inflammation are considered particularly vulnerable, with an increased risk of becoming symptomatic. Positron emission tomography (PET) with 2-deoxy-2-[Fluorine-18] fluoro-D-glucose (18F-FDG) provides valuable metabolic information regarding arteriosclerotic lesions and may be applied for the detection of vulnerable plaque. At present, however, patients are selected for carotid surgical intervention on the basis of the degree of stenosis alone, and not the vulnerability or inflammation of the lesion. During the past decade, research using PET with the glucose analog tracer 18F-fluor-deoxy-glucose, has been implemented for identifying increased tracer uptake in symptomatic carotid plaques, and tracer uptake has been shown to correlate with plaque inflammation and vulnerability. These findings imply that 18F-FDG PET might hold the promise for a new and better diagnostic test to identify patients eligible for carotid endarterectomy. The rationale for developing diagnostic tests based on molecular imaging with 18F-FDG PET, as well as methods for simple clinical PET approaches, are discussed. This is a systematic review, following Preferred Reporting Items for Systematic Reviews guidelines, which interrogated the PUBMED database from January 2001 to November 2019. The search combined the terms, “atherosclerosis,” “inflammation,” “FDG,” and “plaque imaging.” The search criteria included all types of studies, with a primary outcome of the degree of arterial vascular inflammation determined by 18F-FDG uptake. This review examines the role of 18F-FDG PET imaging in the characterization of atherosclerotic plaques.