bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social Memory of the Greek‐Turkish Population Exchange in Daily Life: A Case Study of a Tobacco‐Producing Village in Turkey
Authors: Karakılıç İlhan Zeynep 
Published: October 2020

AbstractThis article aims to understand how villagers whose ancestors had to migrate to Turkey from Greece in 1924 as a result of the Greek‐Turkish population exchange remember their past. Within a theoretical framework built around the concept of habitus from Bourdieu’s oeuvre, social memory, and identity, I argue that social memory finds a practical place in the habitus of the villagers and promotes the villagers’ identity through practices. By emphasising the time dimension in the working of habitus, I also discuss how habitus attunes to changing conditions. Based on semi‐ethnographic fieldwork, this article claims that the relationship among habitus, social memory, and identity was established within the framework of everyday lives that revolved around tobacco production and later changed with the transformation of the tobacco market in Turkey after the 1980s.
Academic achievement with cooperative learning using homogeneous and heterogeneous groups
Authors: Wyman Patricia J. , Watson Scott B. 
Published: October 2020

AbstractCooperative learning is a proven teaching strategy that teachers have been using for over 40 years. Teachers often group students heterogeneously so that students who are lower achieving are learning with and from higher achieving students. The purpose of this study was to test homogeneous and heterogeneous grouping while using cooperative learning teaching structure. This study aimed to answer the question of whether students be grouped homogeneously or heterogeneously while participating in cooperative learning. The primary research design for this study was a quasi‐experimental nonequivalent control‐group design. A convenience sample of fifth‐grade students was drawn from a Georgia elementary school in the 2017–2018 school year. The data were analyzed using analysis of covariance (ANCOVA) and paired samplesttests. The ANCOVA was run to compare the scores from the FOSS Survey/Posttest, and the analysis showed no significant difference between the homogeneous and heterogeneous group posttest scores. Both groups made significant gains (as shown by the results of the paired samplest‐tests).
Work's Role in Learning How
Authors: Mosdell Matthew 
Published: October 2020

AbstractAn influential version of intellectualism about knowledge‐how holds that acquiring facts is necessary and sufficient for learning how to do things. I argue that such a view is incompatible with learning to do things through effort and practice, which suggests that intellectualists do not have a coherent way to explain the role of work in our acquisition of knowledge‐how. By way of an alternative, I argue that work serves to establish patterns of thinking that coordinate propositional truths with powers of action.
Secondary antibody deficiency is associated with development of infection in kidney transplantation: Results of a multicenter study
Authors: Sarmiento Elizabeth , Jimenez Maricela , di Natale Marisa , Rodriguez‐Ferrero Marisa , Anaya Fernando , Lopez‐Hoyos Marcos , Rodrigo Emilio , Arias Manuel , Perello Manel , Seron Daniel , Karanovic Boris , Ezzahouri Ikram , Mezzano Sergio , Jaramillo Maria , Calahorra Leticia , Alarcon Alba , Navarro Joaquin , Muñoz Patricia , Carbone Javier 
Published: October 2020

AbstractBackgroundWe performed a multicenter study to assess the association between secondary antibody deficiency (immunoglobulin G [IgG] hypogammaglobulinemia combined with low levels of specific antibodies) and development of infection in kidney transplantation.MethodsWe prospectively analyzed 250 adult kidney recipients at four centers. The assessment points were before transplantation and 7 and 30 days after transplantation. The immune parameters were as follows: IgG, IgA, and IgM and complement factors C3 and C4 tested by nephelometry; specific IgG antibodies to cytomegalovirus (CMV) and IgG and IgG2 antibodies to pneumococcal polysaccharide (anti‐PPS) determined using enzyme‐linked immunosorbent assay. The clinical follow‐up period lasted 6 months. The clinical outcomes were CMV disease and recurrent bacterial infections requiring antimicrobial therapy. Statistics: Multivariate logistic regression.ResultsAt day 7, IgG hypogammaglobulinemia (IgG levels < 700 mg/dL) combined with low IgG anti‐CMV antibody titers (defined as levels < 10 000 units) was present in 12% of kidney recipients. IgG hypogammaglobulinemia combined with low IgG anti‐PPS antibody titers (defined as levels < 10 mg/dL) at 1 month after kidney transplantation were recorded in 16% of patients. At day 7 the combination of IgG hypogammaglobulinemia and low anti‐CMV titers was independently associated with the development of CMV disease (odds ratio [OR], 6.95; 95% confidence interval [CI], 1.17‐41.31; P = .033). At day 30 after transplantation, the combination of IgG < 700 mg/dL and IgG anti‐PPS < 10 mg/dL, was independently associated with recurrent bacterial infection (OR, 5.942; 95% CI, 1.943‐18.172; P = .002).ConclusionIn a prospective multicenter study, early immunologic monitoring of secondary antibody deficiency proved useful for the identification of kidney recipients who developed severe infection.
Trend in ABO‐incompatible RBC transfusion‐related fatalities reported to the FDA, 2000‐2019
Authors: Storch Emily K. , Rogerson Beth , Eder Anne F. 
Published: October 2020

AbstractBackgroundABO‐incompatible red blood cell (RBC) transfusions and acute hemolytic reactions occur infrequently, yet resultant fatalities are reported to the US Food and Drug Administration (FDA) every year. We describe a 20‐year retrospective study of reported mistransfusion cases to identify temporal trends, common causes, and corrective actions taken to prevent recurrence.Study Design and MethodsABO‐incompatible RBC transfusion‐related fatalities reported to the FDA in 2000‐2019 were reviewed for patient demographics, primary attributed cause, contributing factors, and corrective actions.ResultsEighty reported deaths after ABO‐incompatible RBC transfusion occurred in the 20‐year period. A decrease in the number of cases after 2008 was sustained through 2019 (mean 6 cases/y, 2000‐2009 vs 2 cases/y, 2010‐2019). The estimated rate of reported mistransfusion fatalities was 1 per 2 million RBC units transfused in 2000‐2009 and 1 per 7.14 million RBC units in 2010‐2019 (P < .0001). Administration errors (wrong patient or wrong unit transfused) and sample collection errors (wrong blood in tube [WBIT]) significantly decreased over time but remained the most common causes. In all WBIT cases, verification of patients' ABO type with a second sample or historical type was not performed before transfusion; 16 of 19 (84%) institutions that reported corrective actions subsequently instituted this requirement. In the other categories, 22 of 58 (38%) facilities reported plans for technological process improvements, such as electronic patient identification.ConclusionsThe rate of reported fatalities from ABO‐incompatible RBC transfusion has significantly decreased in the past decade. Still, about two cases are reported each year, highlighting gaps in best practices and areas for improvement.
Application of photosynthetic microalgae in the direct desalination pretreatment of seawater
Authors: Ahamefule Chukwuemeka S. , Ugwuodo Chika J. , Idike Priscilla O. , Ogbonna James C. 
Published: October 2020

AbstractThe abilities of three species of freshwater microalgae to grow in, and desalinate untreated and undiluted seawater were investigated. The salinities of the seawater were reduced from 37.5g/L to 26.25 ± 1.33, 27.19 ± 1.33 and 30.0 ± 0.00 g/L by Desmodesmus subspicatus LC172266, Desmodesmus armatus LC172263 and Dictyosphaerium spp. LC172264 on the fourth, eighth and tenth week of the experiment, respectively, while the control had no change in the salinity. D. subspicatus cell concentration initially dropped from 1.25 × 106 cells/ml to 9.68 × 105 cells/ml and then gradually increased to 4.86 × 107 cells/ml by the tenth week. With D. armatus and Dictyosphaerium spp., the cell concentrations increased steadily from 1.25 × 106 cells/ml to 4.97 × 108 cells/ml and 3.25 × 108 cells/ml, respectively. There were increases in the pH during desalination by the three species. This demonstrates the halotolerant potentials of these species and their abilities to reduce the salinity of seawater.
tRNA methyltransferase 10 homologue A (TRMT10A) mutation in a Chinese patient with diabetes, insulin resistance, intellectual deficiency and microcephaly
Authors: Lin Hu , Zhou Xuelian , Chen Xuefeng , Huang Ke , Wu Wei , Fu Junfen , Li Yangxi , Polychronakos Constantin , Dong Guan-Ping 
Published: October 2020

IntroductionLoss-of-function mutations in tRNA methyltransferase 10 homologue A (TRMT10A), a tRNA methyltransferase, have recently been described as a monogenic cause of early-onset diabetes with microcephaly, epilepsy and intellectual disability.Research design and methodsWe report a Chinese young patient who was diagnosed with diabetes mellitus as a result of aTRMT10Amutation.ResultsA homozygous mutation c.496–1G>A inTRMT10Awas identified using targeted next-generation sequencing and confirmed by PCR/Sanger sequencing. In addition to being diagnosed with diabetes, the patient also has microcephaly and intellectual deficiency. The diabetes was due to marked insulin resistance and responded very well to metformin treatment.ConclusionOur case is the first report in the Asian population. It adds to current knowledge ofTRMT10Arelated with young-onset non-insulin-dependent diabetes and confirms the a single previous report of insulin resistance in this syndrome. Genomic testing should be considered in children with non-insulin-dependent diabetes with intellectual disability and microcephaly. A clear genetic diagnosis is helpful for early detection and treatment addressing insulin resistance.
Incidence and predictors of mortality among children admitted to the pediatric intensive care unit at the University of Gondar comprehensive specialised hospital, northwest Ethiopia: a prospective observational cohort study
Authors: Teshager Nahom Worku , Amare Ashenafi Tazebew , Tamirat Koku Sisay 
Published: October 2020

ObjectiveTo determine the incidence and predictors of mortality among children admitted to the paediatric intensive care unit (PICU) at the University of Gondar comprehensive specialised hospital, northwest Ethiopia.DesignA single-centre prospective observational cohort study.ParticipantsA total of 313 children admitted to the ICU of the University of Gondar comprehensive specialised hospital during a one-and-a-half-year period.MeasurementsData were collected using standard case record form, physical examination and patient document review. Clinical characteristics such as systolic blood pressure, pupillary light reflex, oxygen saturation and need for mechanical ventilation (MV) were assessed and documented within the first hour of admission and entered into an electronic application to calculate the modified Pediatric Index of Mortality 2 (PIM 2) Score. We fitted the Cox proportional hazards model to identify predictors of mortality.ResultThe median age at admission was 48 months with IQR: 12–122, 28.1% were infants and adolescents accounted for 21.4%. Of the total patients studied, 59.7% were males. The median observation time was 3 days with (IQR: 1–6). One hundred and two (32.6%) children died during the follow-up time, and the incidence of mortality was 6.9 deaths per 100 person-day observation. Weekend admission (adjusted HR (AHR)=1.63, 95% CI: 1.02 to 2.62), critical illness diagnoses (AHR=1.79, 95% CI: 1.13 to 2.85), need for MV (AHR=2.36, 95% CI: 1.39 to 4.01) and modified PIM 2 Score (AHR=1.53, 95% CI: 1.36 to 1.72) were the predictors of mortality.ConclusionThe rate of mortality in the PICU was high, admission over weekends, need for MV, critical illness diagnoses and higher PIM 2 scores were significant and independent predictors of mortality.
Turnover intention among primary health workers in China: a systematic review and meta-analysis
Authors: He Rongxin , Liu Jinlin , Zhang Wei-Hong , Zhu Bin , Zhang Ning , Mao Ying 
Published: October 2020

ObjectivesTo analyse the prevalence and determinants of turnover intention (TI) among primary health workers (PHWs) in China to provide evidence for improving retention measures.DesignSystemic review and meta-analysis.Data sourcesFour English-language databases (PubMed, EMBASE, Cochrane Library, PsycINFO) and three Chinese databases (CNKI, CSPD, CBM) were searched up to October 2019.Eligibility criteriaEligible studies were observational or descriptive studies conducted in mainland China. The prevalence of TI among health workers and related factors had to be explicitly reported in each included study.Data extraction and synthesisData were extracted by one author and reviewed independently by two other authors. For each factor analysed by a meta-analysis, the factor was required to be the same across different studies, and at least three studies had to include it. The quality of studies was assessed using the Newcastle–Ottawa Scale and heterogeneity was evaluated using the I2 statistic.ResultsWe identified 16 cross-sectional studies investigating a total of 37 672 PHWs. The prevalence of TI was 30.4%. Subgroup analysis revealed that the highest prevalence was observed in the community primary healthcare institutions and the eastern provinces of China. Meta-analyses indicated that 21 factors were significantly associated with TI, including demographic factors (gender, age, education, marital status), job characteristic factors (title, work seniority, remuneration, social status, organisational affiliation, work stress) and job satisfaction factors (learning and training opportunity, interpersonal relationship, work condition and environment, and so on).ConclusionThis study highlights the problem of TI among PHWs in China. Efforts should be made to improve conditions in both work-related areas and areas outside of work. Policymakers should continue to improve reward systems, the construction of infrastructure and promotion systems, and pay more attention to PHWs’ lives outside of work and meet their living needs.
Cohort profile: the Alberta Prostate Cancer Research Initiative (APCaRI) Registry and Biorepository facilitates technology translation to the clinic through the use of linked, longitudinal clinical and patient-reported data and biospecimens from men in Alberta, Canada
Authors: Vasquez Catalina , Kolinsky Michael , Djebah Rume , Uhlich Maxwell , Donnelly Bryan , Fairey Adrian S , Hyndman Eric , Usmani Nawaid , Wu Jackson , Venner Peter , Ruether Dean , Todd Gerald , Chetner Michael , Crump R Trafford , Beatty Perrin H , Lewis John D 
Published: October 2020

PurposeThe Alberta Prostate Cancer Research Initiative (APCaRI) Registry and Biorepository was established in 2014 by the APCaRI to facilitate the collection of clinical and patient-reported data, biospecimen, to measure prostate cancer outcomes and to support the development and clinical translation of innovative technologies to better diagnose and predict outcomes for patients with prostate cancer.ParticipantsMen suspected with prostate cancer and referred to Urology centres in Alberta were enrolled in the APCaRI 01 study, while men with a prior prostate cancer diagnosis participated in the APCaRI 03 study from 1 July 2014 to 30 June 2019. The APCaRI Registry and Biorepository links biospecimens and data from a wide representation of patients drawn from an Alberta population of more than 4 million.Findings to dateFrom 1 July 2014 to 30 June 2019, total APCaRI 01 and 03 study recruitment was 3754 men; 142 (4%) of these men withdrew in full, 65 men (2%) withdrew biospecimens and 123 men (3%) died of any cause. Over this same time, 8677 patient-reported outcome measure (PROM) surveys and 7368 biospecimens were collected and are available from the registry and biorepository, respectively. The data entry error rate was 0.8% and 0.95% for critical and non-critical values, respectively, and 1.8% for patient-reported surveys.Future plansThe APCaRI Registry and Biorepository will collect longitudinal data and PROM surveys until 2024, patient outcomes up to 25 years after recruitment and biospecimen storage for up to 25 years. The APCaRI cohorts will continue to provide data and samples to researchers conducting retrospective studies. The richness of the data and biospecimens will complement many different research questions, ultimately to improve the quality of care for men with prostate cancer.
Effects of sulforaphane on cognitive function in patients with frontal brain damage: study protocol for a randomised controlled trial
Authors: Liu Fangkun , Huang Jing , Hei Gangrui , Wu Renrong , Liu Zhixiong 
Published: October 2020

IntroductionMany patients with frontal brain damage show serious cognitive function deficits, which hamper their quality of life and result in poor clinical outcomes. Preclinical research has shown that sulforaphane can significantly improve spatial localisation and working memory impairment after brain injury. The primary aim of this double-blind randomised controlled clinical trial is to assess the efficacy of sulforaphane for improving cognitive function in patients with frontal brain damage.Methods and analysisNinety eligible patients will be randomly allocated to an active treatment or a placebo group in a 2:1 ratio. Participants will undergo a series of cognitive and neuropsychiatric tests at baseline (week 0) and after 12 weeks to determine the effect of sulforaphane on cognition. Magnetic resonance spectrum of the brain will be studied using the 3T MRIs of the brain to detect brain metabolites markers, including N-acetyl aspartate, glutamate (Glu), glutathione (GSH) and γ-aminobutyric acid (GABA). Blood brain-derived neurotrophic factor, Glu, GSH and GABA levels and gut microbiota will also be assessed over this period. This study will also evaluate long-term outcomes of brain trauma, brain tumours and cerebrovascular disease via exploratory analyses. The primary outcome will be the difference in scores of a battery of cognitive tests after 12 weeks of sulforaphane treatment. The secondary outcomes will be changes in the Functional Activities Questionnaire (FAQ), the Patient Health Questionnaire (PHQ-9), the Self-Rating Anxiety Scale, the changes in T1-weighted MRI and resting-state functional MRI findings, and changes in brain and blood metabolic markers and gut microbiota at weeks 0 and 12. We expect that sulforaphane will yield favourable results in treating memory and learning deficits for patients with frontal brain damage. Cognitive functional treatment may also improve brain trauma, brain tumours and cerebrovascular outcomes.Ethics and disseminationThe study protocol has been approved by the Medical Ethics committee of the Xiangya Hospital of Central South University (No. 2017121019). The results will be disseminated in peer-reviewed journals and at international conferences.Trial registration numberThis trial was registered on Clinicaltrials.gov on 31 January 2020 (NCT04252261). The protocol version is V.1.0 (20 December 2019).
Cardiovascular risk factor documentation and management in primary care electronic medical records among people with schizophrenia in Ontario, Canada: retrospective cohort study
Authors: O’Neill Braden , Kalia Sumeet , Aliarzadeh Babak , Sullivan Frank , Moineddin Rahim , Kelly Martina , Greiver Michelle 
Published: October 2020

ObjectivesIn order to address the substantial increased risk of cardiovascular disease among people with schizophrenia, it is necessary to identify the factors responsible for some of that increased risk. We analysed the extent to which these risk factors were documented in primary care electronic medical records (EMR), and compared their documentation by patient and provider characteristics.DesignRetrospective cohort study.SettingEMR database of the University of Toronto Practice-Based Research Network Data Safe Haven.Participants197 129 adults between 40 and 75 years of age; 4882 with schizophrenia and 192 427 without.Primary and secondary outcome measuresDocumentation of cardiovascular disease risk factors (age, sex, smoking history, presence of diabetes, blood pressure, whether a patient is currently on medication to reduce blood pressure, total cholesterol and high-density lipoprotein cholesterol).ResultsDocumentation of cardiovascular risk factors was more complete among people with schizophrenia (74.5% of whom had blood pressure documented at least once in the last 2 years vs 67.3% of those without, p>0.0001). Smoking status was not documented in 19.8% of those with schizophrenia and 20.8% of those without (p=0.0843). Factors associated with improved documentation included older patients (OR for ages 70–75 vs 45–49=3.51, 95% CI 3.26 to 3.78), male patients (OR=1.39, 95% CI 1.33 to 1.45), patients cared for by a female provider (OR=1.52, 95% CI 1.12 to 2.07) and increased number of encounters (OR for ≥10 visits vs 3–5 visits=1.53, 95% CI 1.46 to 1.60).ConclusionsDocumentation of cardiovascular risk factors was better among people with schizophrenia than without, although overall documentation was inadequate. Efforts to improve documentation of risk factors are warranted in order to facilitate improved management.
Predictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population
Authors: Yu Peng , Huang Teng , Hu Senlin , Yu Xuefeng 
Published: October 2020

ObjectivesIndividuals with obesity especially excessive visceral adiposity have high risk for incident hypertension. Recently, a new algorithm named relative fat mass (RFM) was introduced to define obesity. Our aim was to investigate whether it can predict hypertension in Chinese population and to compare its predictive power with traditional indices including body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR).DesignA 6-year prospective study.SettingNine provinces (Hei Long Jiang, Liao Ning, Jiang Su, Shan Dong, He Nan, Hu Bei, Hu Nan, Guang Xi and Gui Zhou) in China.ParticipantsThose without hypertension in 2009 survey and respond in 2015 survey.InterventionLogistic regression were performed to investigate the association between RFM and incident hypertension. Receiver operating characteristic (ROC) analysis was performed to compare the predictive ability of these indices and define their optimal cut-off values.Main outcome measuresIncident hypertension in 2015.ResultsThe prevalence of incident hypertension in 2015 based on RFM quartiles were 14.8%, 21.2%, 26.8% and 35.2%, respectively (p for trend <0.001). In overall population, the OR for the highest quartile compared with the lowest quartile for RFM was 2.032 (1.567–2.634) in the fully adjusted model. In ROC analysis, RFM and WHtR had the highest area under the curve (AUC) value in both sexes but did not show statistical significance when compared with AUC value of BMI and WC in men and AUC value of WC in women. The performance of the prediction model based on RFM was comparable to that of BMI, WC or WHtR.ConclusionsRFM can be a powerful indictor for predicting incident hypertension in Chinese population, but it does not show superiority over BMI, WC and WHtR in predictive power.