bluuebunny/crossref_metadata_2025_split huggingface dataset:
It takes a community to care for the sick and disabled
Authors: MacVane Phipps Fiona 
Published: October 2019

Purpose
The purpose of this paper is to provide a broad overview of the articles published in the current issue.

Design/methodology/approach
The review editor reads all articles accepted for the current issue of IJHG, identifying common themes and selecting other relevant articles to explore these themes more fully.

Findings
The findings of this review indicate that the most effective way to care for the sick or disabled is with community involvement.

Practical implications
The practical implications are that the review helps readers to gain a better understanding of the journal content and how for each issue, common themes can be developed and discussed.

Originality/value
No other Emerald Journal has a review section of this type so it is a unique selling point for IJHG.
Ambidextrous supply chain managers in a slow clockspeed industry: evidence from a Brazilian adhesive manufacturer
Authors: Souza-Luz Aruana Rosa , Gavronski Iuri 
Published: October 2019

PurposeConventional wisdom posits that firms in slow clockspeed industries usually favor exploitation over exploration, prioritizing the need to increase efficiency, reduce costs and invest in process improvements. However, what happens when such firms face structural changes in the long run? The authors claim that even firms in slow clockspeed industries should be ambidextrous, that is, they should develop both exploration and exploitation capabilities. Supply chain (SC) managers are key players in enabling organizational ambidexterity. This paper aims to identify the abilities that characterize the ambidextrous SC managers.Design/methodology/approachThe authors collected data from an in-depth case study through ethnographic research, non-participant observation and interviews with SC managers at a Brazilian chemical firm embedded in a slow clockspeed network of clients. These longitudinal data were used to demonstrate the process of implementing new projects in an SC department.FindingsThe authors propose a set of key abilities that enable ambidexterity in SC managers for them to contribute effectively to the SC exploration and exploitation practices: a holistic yet focused view; prior experience in multiple functional areas; technical knowledge; openness towards network connectivity; openness to sharing ideas with other managers; empathy; and entrepreneurial capabilities.Research limitations/implicationsThis paper contributes to the SCM ambidexterity literature by bringing to light the abilities of successful ambidextrous SC managers. The seven abilities identified are discussed. The authors formulate theoretical propositions on how these abilities enable SC managers’ ambidexterity.Practical implicationsThis study provides SC managers with the knowledge of a set of individual abilities they should develop among their SC personnel to offer a more suitable environment in their departments for ambidexterity to take place. In addition, these abilities can be used as screening criteria in personnel selection processes to increase the proportion of ambidextrous employees within the firm. The identified characteristics could also be used as recruitment criteria for managerial positions in SCM.Originality/valueThis research advances SC literature by studying SC managers through the lens of the organizational ambidexterity literature. Using a combination of case study, non-participant observation and ethnographic research, the authors derive a set of propositions for the characteristics of ambidextrous SC managers.
Detection of small target in sea clutter via multiscale directional Lyapunov exponents
Authors: Wang Rui , Li Xiangyang , Ma Hongguang , Zhang Hui 
Published: October 2019

Purpose
This study aims to provide a new method of multiscale directional Lyapunov exponents (MSDLE) calculated based on the state space reconstruction for the nonstationary time series, which can be applied to detect the small target covered by sea clutter.

Design/methodology/approach
Reconstructed state space is divided into non-overlapping submatrices whose columns are equal to a predetermined scale. The authors compute eigenvalues and eigenvectors of the covariance matrix of each submatrix and extract the principal components σip and their corresponding eigenvectors. Then, the angles ψip of eigenvectors between two successive submatrices were calculated. The curves of (σip, ψip) reflect the nonlinear dynamics both in kinetic and directional and form a spectrum with multiscale. The fluctuations of (σip, ψip), which are sensitive to the differences of backscatter between sea wave and target, are taken out as the features for the target detection.

Findings
The proposed method can reflect the local dynamics of sea clutter and the small target within sea clutter is easily detected. The test on the ice multiparameter imaging X-ban radar data and the comparison to K distribution based method illustrate the effectiveness of the proposed method.

Originality/value
The detection of a small target in sea clutter is a compelling issue, as the conventional statistical models cannot well describe the sea clutter on a larger timescale, and the methods based on statistics usually require the stationary sea clutter. It has been proven that sea clutter is nonlinear, nonstationary or cyclostationary and chaotic. The new method of MSDLE proposed in the paper can effectively and efficiently detect the small target covered by sea clutter, which can be also introduced and applied to military, aerospace and maritime fields.
Choosing prevention or cure when mitigating biodiversity loss: Trade‐offs under ‘no net loss’ policies
Authors: Bull Joseph W. , Milner‐Gulland Eleanor‐Jane 
Published: October 2019

Abstract

Biodiversity cannot always be conserved. Economic development activities can result in biodiversity losses, but also increase human well‐being, so trade‐offs must sometimes be made between conservation and development. An alternative strategy to avoidance of impacts through the strict protection of biodiversity (‘prevention’) is to permit certain biodiversity losses and fully compensate for them through offsets elsewhere (‘cure’).

Here, we build a stochastic simulation model to explore trade‐offs between biodiversity loss prevention and cure, in the context of development under ‘no net loss’ (NNL) biodiversity policies. Our model implements a Management Strategy Evaluation framework, monitoring outcomes using four different performance metrics: total biodiversity, net biodiversity, total economic activity and development activity.

We find that a ‘cure’ strategy can potentially perform just as well as a prevention strategy in terms of biodiversity objectives, while outperforming the latter from an economic perspective. However, this does not undermine the need for a mitigation hierarchy, and the best‐performing strategy depends strongly upon both the degree of compliance with the NNL policy and upon underlying ecological parameters.

Perhaps counterintuitively, when evaluated as advised by the technical literature (i.e. against an appropriate counterfactual scenario), we find that net biodiversity outcomes are highest when natural ecosystem recovery rates are slow (so long as development rates are also slow).

Finally, using the illustrative example of US wetlands, we suggest that real‐world NNL policies could already be driving landscape‐scale avoidance of development impacts under a ‘prevention’ approach.

Policy implications. No net loss (NNL) biodiversity policy is currently being developed or implemented by over 100 countries world‐wide and incorporated into environmental safeguards by multinational lenders. The socioecological model presented here can be used to advise decision makers about the best structure for nascent NNL policy on the basis of region‐specific ecosystem recovery rates, development activity, legal compliance and monitoring uncertainty. Furthermore, the model presents a means for estimating the degree to which biodiversity impacts are avoided by developers under NNL—an important monitoring consideration given that ensuring high levels of avoidance is crucial to robust NNL policy, but which has to date evaded assessment through purely empirical means.
Co‐administration of N‐acetylcysteine and dexmedetomidine plays a synergistic effect on protection of LPS‐induced acute lung injury via correcting Th1/Th2/Th17 cytokines imbalance
Authors: Song Qitai , Lin Li , Chen Lin , Cheng Lingxia , Zhong Wu 
Published: October 2019

AbstractRecently both N‐acetylcysteine (NAC) and Dexmedetomidine (DEX) have shown emerging roles in protection of acute lung injury (ALI). However, how their protective roles work and whether they can provide synergistic effects in ALI remain unknown. Here we explored it from the hot research viewpoint of Th1/Th2/Th17 cytokines balance. Lipopolysaccharide (LPS)‐induced ALI was established and treated with NAC and/or DEX. Mice were divided into Sham group, ALI group, NAC group, DEX group and NAC+DEX group. Mice were sampled at 6, 12 and 24 hours after the model construction. Histopathology, wet to dry ratio and myeloperoxidase (MPO) activity were assessed in lung tissues. Protein concentration and cell count were assessed in bronchoalveolar lavage fluid (BALF). Th1/Th2/Th17 cytokines were assessed in plasma, BALF and lung homogenate. ALI‐induced lung morphological damage, edema and aberrant MPO activity can be attenuated by NAC or DEX and mostly by NAC+DEX. NAC with DEX significantly reduced ALI‐induced protein leakage and cell infiltration in BALF. Th1/Th2/Th17 cytokines imbalance aggravated with ALI progression. NAC, DEX and especially NAC+DEX can effectively correct these unbalanced cytokines. Galectin‐9 and Tim‐3 were transcriptionally up‐regulated in ALI. Combination of NAC with DEX obtained a maximum effect on decreasing Galectin‐9/Tim‐3 expression. In summary, Th1/Th2/Th17 cytokines imbalance is newly found to participate in LPS‐induced ALI. NAC or DEX administration can attenuate ALI by rebalancing Th1/Th2/Th17 cytokines. Their protective roles can be enhanced when co‐administration, because DEX may relieve the Galectin‐9/Tim‐3 axis‐mediated immune suppression.
Pralidoxime administered during cardiopulmonary resuscitation facilitates successful resuscitation in a pig model of cardiac arrest
Authors: Jung Yong Hun , Lee Hyoung Youn , Jeung Kyung Woon , Lee Byung Kook , Youn Chun Song , Yun Seong Woo , Heo Tag , Min Yong Il 
Published: October 2019

AbstractPralidoxime is a common antidote for organophosphate poisoning; however, studies have also reported pralidoxime's pressor effect, which may facilitate the restoration of spontaneous circulation (ROSC) after cardiac arrest by improving coronary perfusion pressure (CPP). We investigated the immediate cardiovascular effects of pralidoxime in anaesthetised normal rats and the effects of pralidoxime administration during cardiopulmonary resuscitation (CPR) in a pig model of cardiac arrest. To evaluate the immediate cardiovascular effects of pralidoxime, seven anaesthetised normal rats received saline or pralidoxime (20 mg/kg) in a randomised crossover design, and the responses were determined using the conductance catheter technique. To evaluate the effects of pralidoxime administration during CPR, 22 pigs randomly received either 80 mg/kg of pralidoxime or an equivalent volume of saline during CPR. In the rats, pralidoxime significantly increased arterial pressure than saline (P = .044). The peak effect on arterial pressure was observed in the first minute. In a pig model of cardiac arrest, CPP during CPR was higher in the pralidoxime group than in the control group (P = .002). ROSC was attained in three animals (27.3%) in the control group and nine animals (81.8%) in the pralidoxime group (P = .010). Three animals (27.3%) in the control group and eight animals (72.2%) in the pralidoxime group survived the 6‐hour period (P = .033). In conclusion, pralidoxime had a rapid onset of pressor effect. Pralidoxime administered during CPR led to significantly higher rates of ROSC and 6‐hour survival by improving CPP in a pig model.
Seed germination of exotic and native winter annuals differentially responds to temperature and moisture, especially with climate change scenarios
Authors: Hicks Rachael N. , Wang Fenglan , Hidayati Siti N. , Walck Jeffrey L. 
Published: October 2019

AbstractSeeds of winter annuals require a summer after‐ripening period for dormancy loss and low autumn temperatures for germination. With current and future changes in moisture and temperature, we tested the effects of warming along a relative humidity (RH) gradient on dormancy loss and effects of decreased diurnal temperature range (DTR) on germination. We further reasoned that the effects of changes in these variables would be disproportionate between the exotic and native winter annuals. Seeds of exotic species (Buglossoides arvensis, Lamium purpureum and Ranunculus parviflorus) and co‐occurring native species (Galium aparine, Paysonia stonensis and Plantago virginica) were collected in middle Tennessee. After‐ripening occurred over a 15–100% RH gradient at 25 and 30°C and germination was tested at 20/10 and 20/15°C. Niche breadth was calculated using Levins' B. Fresh Ranunculus seeds had high germination and those of other species did not. Germination for these species increased with after‐ripening, mostly across the RH gradient irrespective of temperature. A decrease in DTR showed mixed results – the extreme being Ranunculus with no germination at 20/15°C. Most exotic species had wider germination niche breadths than native species. With climate change, we suggest that a decrease in DTR may have a larger effect on germination than increasing moisture or warming on dormancy break. Moreover, there is not a clear‐cut winner with climate change when we compare exotic versus native species because the responses of our six species were species specific.
Annual migratory patterns of Far East Greylag Geese (Anser anser rubrirostris) revealed by GPS tracking
Authors: LI Xianghuang , WANG Xin , FANG Lei , BATBAYAR Nyambayar , NATSAGDORJ Tseveenmyadag , DAVAASUREN Batmunkh , DAMBA Iderbat , XU Zhenggang , CAO Lei , FOX Anthony David 
Published: October 2019

AbstractTwenty Far East Greylag Geese, Anser anser rubrirostris, were captured and fitted with Global Positioning System/Global System for Mobile Communications (GPS/GSM) loggers to identify breeding and wintering areas, migration routes and stopover sites. Telemetry data for the first time showed linkages between their Yangtze River wintering areas, stopover sites in northeastern China, and breeding/molting grounds in eastern Mongolia and northeast China. 10 of the 20 tagged individuals provided sufficient data. They stopped on migration at the Yellow River Estuary, Beidagang Reservoir and Xar Moron River, confirming these areas as being important stopover sites for this population. The median spring migration duration was 33.7 days (individuals started migrating between 25 February and 16 March and completed migrating from 1 to 9 April) compared to 52.7 days in autumn (26 September–13 October until 4 November–11 December). The median stopover duration was 31.1 and 51.3 days and the median speed of travel was 62.6 and 47.9 km/day for spring and autumn migration, respectively. The significant differences between spring and autumn migration on the migration duration, the stopover duration and the migration speed confirmed that tagged adult Greylag Geese traveled faster in spring than autumn, supporting the hypothesis that they should be more time‐limited during spring migration.
Evolutionary history of mountain voles of the subgenus Aschizomys (Cricetidae, Rodentia), inferred from mitochondrial and nuclear markers
Authors: BODROV Semen Yu. , VASILJEVA Vera K. , OKHLOPKOV Innokentiy M. , MAMAYEV Nikolai V. , ZAKHAROV Evgeniy S. , OLEINIKOV Alexey Yu , GENELT‐YANOVSKIY Evgeniy A. , ABRAMSON Natalia I. 
Published: October 2019

AbstractIn this study, we present an assessment of the evolutionary history and phylogenetic relationships of Asian mountain voles of the subgenus Aschizomys, genus Alticola, based on extensive sampling and phylogenetic analyses of data from mitochondrial and nuclear markers. Two species of this subgenus are widespread in the mountain areas of north‐eastern Asia. However, both their distribution and taxonomic borders remained questionable for more than 100 years. Our study showed discordance in the phylogenetic patterns between nuclear and mtDNA markers. We found that mtDNA in A. lemminus is paraphyletic relative to A. macrotis, but nuclear markers demonstrated reciprocal monophyly. According to species distribution modeling, ranges of A. macrotis and A. lemminus experienced a secondary contact during the Last Glacial Maximum (approximately 22 kyr BP), and thus a hybridization event seems plausible during that period. Species tree analyses recovered a sister group relationship between the two species of the Aschizomys subgenus, with an estimated divergence date of around 0.8 Ma. Our results provided good support for currently recognized subspecies within both A. macrotis and A. lemminus based on mitochondrial and nuclear datasets. A new, yet undescribed form, supposedly of a subspecific status within A. lemminus, was found in the Bureinskiy Range in the Khabarovsk area. This finding expands the current species distribution range further to the southeast.
Mechanisms underlying detection of seed dormancy by a scatter‐hoarding rodent
Authors: SUNDARAM Mekala , HIGDON Ashley E. , WOOD Karl V. , BONHAM Connie C. , SWIHART Robert K. 
Published: October 2019

AbstractThe mechanism underlying detection of seed dormancy by scatter‐hoarding rodents is unclear, although previous work suggests that the pericarp plays an important role in signaling dormancy status. Eastern gray squirrels (Sciurus carolinensis) consume early germinating seeds as they are more likely to perish immediately, whereas dormant seeds tend to be cached. To examine the mechanisms underlying dormancy detection, we characterized physical and chemical differences between germinating and dormant pericarps of northern red oak (Quercus rubra), American chestnut (Castanea dentata) and the BC3 hybrid of Chinese chestnut and American chestnut (Castanea mollissima × C. dentata) using scanning electron microscopy and gas chromatography‐ mass spectrometry. We found that, as seeds break dormancy, the wax layer on the pericarp degrades and is accompanied by the escape of lower molecular weight kernel compounds or lipid metabolism byproducts. Our field experiments showed that squirrels were 4–8 times more likely to consume seeds that were altered to remove pericarp wax coating or that were sprayed with seed chemicals. We argue that dormancy detection by scatter‐hoarding rodents is a complex process involving physical cues such as loss of pericarp wax and chemical cues such as emission of olfactory cues.
Retrospective cohort study on the safety and efficacy of docetaxel in Japanese non‐small cell lung cancer patients with nondialysis chronic kidney disease stage 3b or higher
Authors: Anai Satoshi , Ibusuki Ritsu , Takao Tomoaki , Sakurai Yuko , Hisasue Junko , Takaki Yoichi , Hara Naohiko 
Published: October 2019

AbstractBackgroundIt has been reported that 20% of lung cancer patients have renal impairment caused by chronic kidney disease (CKD). Since docetaxel is predominantly excreted by the hepatobiliary system, it is administered to non‐small cell lung cancer (NSCLC) patients with renal impairment. However, few clinical data are available on the toxicity and efficacy of docetaxel for patients with nondialysis renal impairment. Furthermore, some cases of tubular nephrotoxicity caused by docetaxel in NSCLC patients have been reported. Therefore, a retrospective cohort study was conducted to assess the influence of nondialysis CKD on the toxicity and efficacy of docetaxel in NSCLC patients.MethodsNSCLC patients who received docetaxel were assessed for renal function, occurrence of adverse events and treatment efficacy.ResultsA total of 34 NSCLC patients who received docetaxel were studied. Eight (23.5%) patients had nondialysis CKD stage 3b or higher, with an estimated glomerular filtration rate (eGFR) <45 mL/min/1.73 m2. Although the differences were not statistically significant, the starting dose of docetaxel (mg/m2) was lower (60 mg/m2; 37.5% vs. 69.2%) in patients with an eGFR <45 than that in patients with an eGFR ≥45. No significant association was observed between pretreatment eGFR and hematological and nonhematological toxicities. No significant difference was observed in the disease control rate (62.5% vs. 65.4%, P = 1.000) or in the median overall survival (10.7 vs. 11.7, P = 0.735) between patients with an eGFR <45 and those with an eGFR ≥45.ConclusionDocetaxel is a reasonable option for NSCLC patients with nondialysis CKD stage 3b or higher. Dose reduction of docetaxel is also a possibility for NSCLC patients with CKD stage 3b or higher.
The Informational Effects of Tightening Oil and Gas Disclosure Rules
Authors: Badia Marc , Duro Miguel , Jorgensen Bjorn N. , Ormazabal Gaizka , Christensen Hans B. 
Published: October 2019

ABSTRACTWe exploit two regulatory shocks to examine the informational effects of tightening preexisting mandatory disclosure rules. Canadian National Instrument 51‐101 in 2003 and the U.S. rule “Modernization of Oil and Gas Reporting” in 2009 introduced quasi‐identical amendments which effectively tightened the rules governing oil and gas reserve disclosures in both countries. We document significant changes in firms' reporting outcomes when the new regulations are introduced. We also find that the reserve disclosures filed under the new regulations are more closely associated with stock price changes and with decreases in bid‐ask spreads. Our findings are robust to controlling for other confounding factors such as time trends, other information disclosed simultaneously, financial reporting incentives, mispricing, and monitoring efforts.