bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Impacting Differential Outcomes in the Definitive Radiation Treatment of Anal Cancer Between HIV-Positive and HIV-Negative Patients
Authors: Susko Matthew , Wang Chia-Ching Jackie , Lazar Ann A. , Kim Stephanie , Laffan Angela , Feng Mary , Ko Andrew , Venook Alan P. , Atreya Chloe E. , Van Loon Katherine , Anwar Mekhail 
Published: May 2020

Abstract

Background
Anal squamous cell carcinoma (ASCC) is uncommon, yet seen more frequently in the setting of the human immunodeficiency virus (HIV). Chemoradiotherapy is the definitive modality of treatment for patients with ASCC; this study examines factors impacting clinical outcomes in a large cohort of HIV-positive and HIV-negative patients.

Methods
A retrospective review was conducted of patients treated for nonmetastatic ASCC at a single institution between 2005 and 2018. Freedom from local recurrence (FFLR), freedom from distant metastasis, and overall survival (OS) were calculated using the Kaplan-Meier method, and univariate and multivariate analysis were performed using the Cox proportional hazards model.

Results
During the study period, 111 patients initiated definitive treatment for ASCC. Median age of the entire cohort was 56.7 years (interquartile range, 51.5–63.5), with 52 patients (46.8%) being HIV-positive. At median follow-up of 28.0 months, the 2- and 5-year FFLR were 78.2% (95% confidence interval [CI], 70.4–87.0) and 74.6% (95% CI, 65.8–84.5), respectively. Multivariate analysis revealed time from diagnosis to treatment initiation (median, 8 weeks; hazard ratio, 1.06; 95% CI, 1.03–1.10) to be significantly associated with worse FFLR and OS. HIV-positive patients had a trend toward worse FFLR (log-ranked p = .06). For HIV-positive patients with post-treatment CD4 less than 150 cells per mm3, there was significantly worse OS (log-ranked p = .015).

Conclusion
A trend toward worse FFLR was seen in HIV-positive patients, despite similar baseline disease characteristics as HIV-negative patients. Worse FFLR and OS was significantly associated with increased time from diagnosis to treatment initiation. Poorer OS was seen in HIV-positive patients with a post-treatment CD4 count less than 150 cells per mm3.

Implications for Practice
Human immunodeficiency virus (HIV)-positive patients with anal squamous cell carcinoma can represent a difficult clinical scenario. Definitive radiation with concurrent chemotherapy is highly effective but can result in significant toxicity and a decrease in CD4 count that could predispose to HIV-related complications. As HIV-positive patients have largely been excluded from prospective clinical trials, this study seeks to provide greater understanding of their outcomes with radiation therapy, potential predictors of worse local control and overall survival, and those most at risk after completion of treatment.
Manisa ili kekik (Origanum onites) alanlarında görülen yabancı ot türleri, yoğunlukları, rastlanma sıklıkları
Authors: SOKAT Yildiz 
Published: May 2020

Çalışmada, Manisa İli kekik (Origanum spp.) üretim alanlarında bulunan yabancı ot türleri,
yoğunlukları ve rastlanma sıklıkları araştırılmıştır. Surveyler; 2013 yılında,
tesadüfü olarak seçilen 21 tarlada 705 dekar alanda, iki farklı dönemde
yürütülmüştür. Yabancı ot sayımlarında tarla büyüklüğüne göre, 1/4 m2’lik
çerçeveler atılarak yabancı otların tür bazında sayımları gerçekleştirilmiştir.
Sayımlarda geniş yapraklı yabancı otlar tüm bitki olarak, dar yapraklıların ise
sapları sayılarak değerlendirilmiştir. Elde edilen verilerden m2’deki
yabancı ot yoğunluğu ve rastlanma sıklığı belirlenmiştir. Surveyler sonucunda 25 familyaya ait 46 farklı yabancı ot türü saptanmıştır. Söz konusu türler içerisinde
ikisinin parazit (Cuscuta campestris
L., Orabanche gracilis sm.) tür,
dördünün dar yapraklı, diğerlerinin geniş yapraklı yabancı ot türlerinden
olduğu belirlenmiştir. Geniş
yapraklı yabancı otlar içerisinde en yoğun Convolvulus arvensis L.(1,15 adet/m2), bunu sırasıyla
Lactuca serriola (1,03 adet/m2), Lactuca saligna L. (0,75 adet/m2), Soncus asper (0,62 adet/m2
), Portulaca oleracea L. (0,58 adet/m2)
türlerinin takip ettiği; dar yapraklı yabancı otlarda ise en yoğun Cyperus rotundus L. (2,67 adet/m2)
türünün olduğu, bunu Cynedon dactylon
(0,39 adet/m2) ve Sorghum
halapense L., (0,13 adet/m2)’nin takip ettiği belirlenmiştir.
Yabancı otlardan en sık Convolvulus
arvensis L. (% 99), Lactuca serriola
(% 63), Cypeus rotundus L. (% 49), Sonchus asper L. (% 36) türlerine saptanmıştır.
Analisa Kebutuhan Make Up Water Cooling Tower RSG-GAS pada Daya 30 MW Setelah Revitalisasi
Authors: Busono Pranto , Pujiarta Santosa 
Published: May 2020

Akibat kondisi dan usia dari cooling tower RSG-GAS maka telah dilakukan revitalisasi pada cooling tower tersebut. Cooling tower yang baru mempunyai tipe sama dengan tipe sebelumnya, yaitu tipe Mechanical induced draft, counter flow, Inline, Closed end. Akibat penggantian/revitalisasi cooling tower RSG-GAS maka perlu dilakukan kajian yang berkaitan dengan besarnya kehilangan air. Kehilangan air pada cooling tower terdiri atas: evaporation loss (We), Drift loss (Wd) dan blowdown (Wb). Besarnya kehilangan air berdasarkan desain 93,8074 m3/h, hasil perhitungan 53,1286 m3/h dan hasil pengamatan adalah sebesarnya 39,4548 m3/h. Kehilangan air pada cooling tower perlu dilakukan perhitungan karena berkaitan dengan kemampuan pompa PA-04 dalam mengkompensasi kehilangan air tersebut. Dengan kemampuan pompa PA-04 yang mempunyai kapasitas 100 m3/h, maka dapat dipastikan bahwa pompa PA-04 masih mampu untuk mengkompensasi kehilangan air di cooling tower. Kata kunci : make up water, revitalisasi cooling tower, kehilangan air
CALCULATION OF PROBABILITY OF TRISO PARTICLE FAILURE USING TIMCOAT AND PEBBED CODE
Authors: Wijaya Rokhmadi , Wahid Nuryadin Bebeh , Maulani Khotib , Setiadipura Topan 
Published: May 2020

CALCULATION OF PROBABILITY OF TRISO PARTICLE FAILURE USING TIMCOAT AND PEBBED CODE. The calculation of the failure probability for fuel particles (TRISO) in the HTGR type reactor has been successfully carried out. This study aimed to estimate the failure probability of the fuel particles in the HTR-10 and HTR-PM, as well as to analyze the fuels of those reactors by varying the SiC thickness. The initial layer thickness of SiC in the HTR-10 and HTR-PM is 35 µm. The PEBBED code was used to simulate calculations resulting in the power distribution data, which is then compared with the results from the TIMCOAT simulation process. The TIMCOAT simulation calculation results, which are based on the SiC thickness variation, showed that the thickness failure is smaller if applied to the HTR-10 and HTR-PM. Based on the comparison between the two reactors, the failure probability of HTR-PM fuel particle has the value smaller than that of the HTR-10 with the difference of 10-5 .Keywords: failure particle, HTR-10, HTR-PM, TRISO, TIMCOAT.
ANALISIS NILAI REAKTIVITAS BATANG KENDALI TERAS RSG-GAS SETELAH 30 TAHUN BEROPERASI
Authors: Purwadi Purwadi , Pardi Pardi 
Published: May 2020

ABSTRAK ANALISIS NILAI REAKTIVITAS BATANG KENDALI TERAS RSG-GAS SETELAH 30 TAHUN BEROPERASI. Reaktor RSG-GAS telah beroperasi lebih dari 30 tahun untuk berbagai keperluan seperti produksi radioisotop dan penelitian dalam bidang nuklir, industri, kesehatan, material dll. Setelah beroperasi 30 tahun telah banyak komponen, sistem dan struktur reaktor yang telah menurun unjuk kerjanya sehingga perlu untuk diganti. Setelah mengalami pergantian maka perlu dilakukan analisis sistem batang kendali teras RSG-GAS yang merupakan satu-satu sistem kendali reaktor. Nilai reaktivitas batang kendali teras RSG-GAS diperoleh dari hasil eksperimen. Nilai ini akan dibandingkan dengan hasil perhitungan. Perhitungan nilai reaktivitas batang kendali reaktor RSG-GAS dilakukan dengan metode difusi menggunakan program komputer WIMSD-5B dan Batan-3DIFF. Hasil analisis menunjukan bahwa batang kendali teras RSG-GAS masih layak digunakan untuk mengoperasikan reaktor. Hasil perhitungan dan eksperimen menunjukkan bahwa nilai reaktivitas tidak jauh berbeda dan perbedaan rerata sekitar 10 %. Kata kunci: reaktor RSG-GAS, nilai reaktivitas, batang kendali, komputer Batan-3DIFF .
Evaluation of Improved Tef [Eragrostisteff /Zucc./Trotter] Production Technologies in Central High Lands of Ethiopia
Authors: Gemechu Bekele , Besufekad Amha 
Published: May 2020

A study was carried out to evaluate the performance of improved varieties of tef and production technologies in Becho district of Oromia, Centeral Ethiopia. Five improved tef varieties along with the local were selected and used as treatments (that is, Dega tef (T1), Guduru (T2), Kena (T3), Kora(T4),Quncho(T5) and Local (T6)) arranged in a Randomized Complete Block Design (RCBD) with six replications using six farmers’ fields. Yield and yield related parameters were analyzed using SAS statistical software version 9.0. Economic analysis/profitability, preference/acceptability, gender and nutrition and environmental suitability data recording were performed to compare treatments advantages and identify the best performing varietity/ies. All the yield and yield related components were significantly different between the varieties at 5 % probability level %) except for plant height in which there was no significant difference among varieties. Variety Dega tef gave the highest grain yield with average grain yield of 3610.6kg/ha followed by Quncho and Kora and also had about 40% yield advantage over the local variety with average grain yield of 2577.83kg/ha and had about 116.95%, 110.25% and 90.80 % yield advantage over the national, regional and zonal average yield of tef in 2016/2017 Meher season of CSA data respectively. Based on farmer’s preference analysis variety Dega tef had high acceptability (75%) followed by Quncho (73%) and Kora (70%). Guduru variety has the least in acceptability (21%). As the result from the economic analysis showed that Dega tef variety had the maximum net benefit (79,536.69birr/ha) followed by Quncho (67,106.97birr/ha) and Kora (63,746.96birr/ha). Variety Guduru had the least net benefit result of about 53,648.17birr/ha. Based on the rules of decision making and the integrated scoring set for technology validation, two of the three improved varieties meet the requirements to be recommended. Therefore, we recommend Dega tef, Quncho, and Kora varieties for Becho areas and other areas with similar agro-ecological conditions in the central highlands of Ethiopia.
Study of consumption preferences and frequency of selected vegetables among female students of dietetics
Authors: Całyniuk Beata , Bucka Izabela , Karpe Jacek , Bucki Bogusław 
Published: May 2020

WstępSposób odżywiania ma duży wpływ na zdrowie człowieka. Codzienne spożywanie warzyw ma korzystny wpływ na prawidłowe funkcjonowanie organizmu. Powinny zatem być składnikiem codziennej diety, z uwagi na zawartość witamin, znaczną ilość błonnika pokarmowego oraz inne składniki pożywienia niezbędne dla zdrowia w jego różnych aspektach. Celem badań było określenie stopnia preferencji oraz częstotliwości spożycia wybranych warzyw wśród studentek kierunku dietetyka, które powinno ewoluować w miarę poszerzania wiedzy o żywieniu człowieka.Materiał i metodyNarzędziem badawczym była ankieta, w której pytano o preferencje i częstotliwość spożycia wybranych warzyw. Badanie przeprowadzono wśród studentek dietetyki Śląskiego Uniwersytetu Medycznego.WynikiNie wykazano istotnych różnic pomiędzy częstotliwością spożycia wybranych warzyw oraz preferencji wyborów, za wyjątkiem jarmużu. Najwyższy stopień preferencji uzyskały pomidory, marchew, ogórki, które były spożywane co najmniej 3–4 razy w tygodniu.WnioskiNie obserwowano istotnych zmian preferencji wybranych warzyw wśród studentek w okresie trwania studiów. W badanej grupie studentek zaobserwowano istotny wzrost częstości spożycia jarmużu. Najbardziej preferowanymi i najczęściej spożywanymi warzywami były: pomidory, marchew, ogórki, papryka.
ASSESSING THE SUITABILITY OF PIONEER SPECIES FOR SECONDARY FOREST RESTORATION IN BENIN IN THE CONTEXT OF GLOBAL CLIMATE CHANGE
Authors: Gbètoho Alain Jaures , Aoudji Augustin K. N. , Roxburgh Lizanne , Ganglo Jean C. 
Published: May 2020

In this study, species distribution model- ling (SDM) was applied to the manage- ment of secondary forests in Benin. This study aims at identifying suitable areas where the use of candidate pioneer spe- cies, such as Lonchocarpus sericeus and Anogeissus leiocarpa, could be targeted to ensure at low cost, currently and in the context of global climate change, fast reconstitution of secondary forests and disturbed ecosystems and the recovery of their biodiversity. Using occurrence records from the Global Biodiversity Infor- mation Facility (GBIF) website and cur- rent environmental data, the factors that affected the distribution of the species were assessed in West Africa. The models developed in MaxEnt and R software for West Africa only, for both species, showed good predictive power with AUC > 0.80 and AUC ratios well above 1.5. The results were projected in future climate at the horizon 2055, using AfriClim data under rcp4.5 and rcp8.5 and suggested a little reduction in the range of L. seri- ceus and any variation for A. leiocarpa. The potential distribution of the two spe- cies indicated that they could be used for vegetation restoration activities both now and in the mid-21st century. Improve- ment are needed through the use of com- plementary data, the extension to others species and the assessment of uncertain- ties related to these predictions.
EVALUATION OF MODIFICATED STEEL SCAFFOLD APPLICATION AS A TEMPORARY SUPPORT FOR THE TRANSFER BEAM COLUMN STRUCTURE (CASE STUDY : TUNJUNGAN PLAZA 6 PROJECT IN SURABAYA)
Authors: Nugraha Herdhyasmara Rizki , Arifin Syamsul , Wahyuningtyas Winda Tri 
Published: May 2020

Scaffolding is one of the important components in the concrete job. Its role of supporting the work of concrete, the structure of scaffold should be taken into account appropriately. Failure in planning of the scaffold will result disturb on a concrete job. Along with the development of the times, the construction services company developed a method in the work of the scaffolding. One example that is replace the scaffolding with steel profiles. The purpose of the advent of modificated steel scaffold is to allow the structure of the scaffold to be able to sustain a larger burden compared with the structure of the scaffolding. Behind the goals to be achieved, there is the risk that may occur. For example, swelling costs resulting from the use of steel profiles for the components of the structure of the scaffold. Therefore, must to be evaluated so as to achieve greater efficiency in terms of steel profile dimensions as well as the cost product of use modificated steel scaffold. Modificated steel scaffold in Tunjungan Plaza 6 projects were used to shore up the structure Transfer Beam named megatruss. From the results of this research obtained efficiency of steel profile dimensions for the scaffold structure. So obtained also the efficiency to cost product the use of scaffolding megatruss is equal of 20,05%.
Perancah merupakan komponen penting dalam pekerjaan beton sehingga struktur harus diperhitungkan dengan tepat. Kegagalan dalam perencanaan perancah akan berakibat pada kegagalan struktur saat pekerjaan beton. Saat ini perusahaan jasa konstruksi mengembangkan metode dalam pekerjaan perancah, salah satu contohnya yaitu mengganti struktur perancah (scaffolding) dengan perancah dari profil baja. Tujuan munculnya perancah baja modifikasi ini adalah untuk memungkinkan struktur perancah untuk dapat menopang beban yang lebih besar dibandingkan dengan struktur perancah (scaffolding) pada umumnya. Dampak dari perubahan perancah berakibat pada pembengkakan biaya akibat dari penggunaan profil baja. Oleh sebab tersebut, maka perlunya dilakukan evaluasi agar tercapainya efisiensi dari segi dimensi profil bajanya serta biaya produksi dari penggunaan perancah baja modifikasi. Perancah baja modifikasi pada proyek Tunjungan Plaza 6 Surabaya yang digunakan untuk menopang struktur Transfer Beam Column diberi nama megatruss. Dari hasil penelitian ini didapatkan hasil bahwa diperoleh efisiensi dimensi profil baja untuk struktur perancah tersebut. Sehingga diperoleh pula efisiensi untuk biaya produksi (cost product) penggunaan perancah megatruss yaitu sebesar 20,05%.
THE EFFECT OF USING A COUNTDOWN TIMER ON THE SIGNALIZED INTERSECTIONS PERFORMANCE IN MALANG CITY
Authors: Maliq Tatang Maulana , Sulistio Harnen , Djakfar Ludfi , Sulistyono Sonya 
Published: May 2020

The high growth of the population in Malang will trigger an increase in the activity of its, resulting in increased traffic. Increased traffic demands will add to traffic congestion problems on roads and intersections. One way of traffic engineering to improve signaled intersection performance is to equip traffic signals with countdown timers. This additional instrument serves to inform the duration of the signal setup time. This study aims to determine the effect of countdown timer use on saturation flow, performance and safety factor signalized intersection in Malang. The paired sample t-teste statistical method is used to see the influence of the countdown timer on saturation flow, and the impact on the performance and safety of the intersection arm. The use of countdown timer can increase the value of saturation flow, so the capacity of the intersection also increased 5-22% with decreasing delay time 5-13 sec/smp. But the less positive impact on the safety factor intersection, because there is an increase in the movement of vehicles before the green time.
Tingginya pertumbuhan jumah penduduk di Kota Malang akan memicu peningkatan aktifitas penduduk sehingga berdampak pada meningkatnya lalu lintas. Peningkatan tuntutan lalu lintas akan menambah masalah kemacetan lalu lintas pada ruas jalan dan simpang. Salah satu cara rekayasa lalu lintas untuk meningkatkan kinerja simpang bersinyal adalah melengkapi sinyal lalu lintas dengan countdown timer. Instrumen tambahan ini berfungsi menginformasikan durasi waktu pengaturan sinyal. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan countdown timer terhadap arus jenuh , kinerja dan faktor keselamatan simpang bersinyal di Kota Malang. Metode statistik paired sample t-teste digunakan untuk melihat pengaruh countdown timer terhadap arus jenuh, dan dampak pada kinerja serta keselamatan lengan simpang. Penggunaan countdown timer mampu meningkatkan nilai arus jenuh, sehingga kapasitas lengan simpang juga mengalami peningkatan 5-22% dengan penurunan waktu tundaan 5-13 detik/smp. Tetapi kurang berdampak positif terhadap faktor keselamatan simpang, karena terjadi peningkatan pergerakan kendaraan sebelum waktu hijau.
PEAK DISCHARGE ESTIMATION OF WELANG WATERSHED IN PASURUAN REGENCY
Authors: Febriyanto Andreyan , Hidayah Entin , Halik Gusfan 
Published: May 2020

Peak runoff has an important role in flood control.In flood control, the data of peak runoff is needed to anticipate the flood and rain fall modeling estimation is required with the help of HEC-HMS Software. From modeling result on February 3, 2007 researcher got calibration value of simulation of peak discharge 17,9 and peak discharge observation is 16,7 with a value of effectiveness (Nash) of 0.873. Model validation test on 9,10 February and 7 March 2007 resulted in value (Nash) of 0.826, 0.742 and 0.656.
Debit puncak mempunyai peranan penting dalam pengendalian banjir. Dalam pengendalian banjir, data dari limpasan hujan dibutuhkan untuk mengantisipasi banjir dan pemodelan estimasi curah hujan dibutuhkan dengan adanya bantuan dari Software HEC-HMS. Hasil pemodelan pada tanggal 3 Februari 2007 didapat nilai kalibrasi simulasi debit puncak sebesar 17,9 m³/s dan observasi debit puncak sebesar 16,7 m³/s dengan nilai efektifitas (Nash) sebesar 0,873. Uji validasi model pada tanggal 9,10 Februari dan 7 Maret 2007 menghasilkan nilai (Nash) sebesar 0,826, 0,742 dan 0,656.
THE INFLUENCE OF COMPOSTING TIME AND COMPOSITION OF ORGANIC WASTE COMPOST AGAINST THE GROWTH RATE OF LONG BEAN LEAVES (VIGNA CYLINDRICA (L.)
Authors: Afifah Anshah Silmi , Prajati Gita , Suryawan I Wayan Koko 
Published: May 2020

The landfill's capacity is currently decreasing, so solid waste reduction needs to be increased. Organic solid waste is generated by daily activities. The objective of the study was to determine the composting and composition of the growth of leaves of the long bean plant (Vigna cylindrical (L.)). Methods used in the composting process is the takakura method. The 80% compositions of compost are spinach waste. The composting process accelerated by the addition of local microorganisms (MOL) from fruit and compost to accelerate decomposed of organic waste. Variables on this research were functions of the time for the composting process and the amount of compost with the soil to the long bean plant (Vigna cylindrical (L.)). Compost collection time was determined as a research variable with variations on 14, 28, and 42 days, while variations in compost and soil composition tested on a long bean plant (Vigna cylindrical (L.)) of 1: 1 and 1: 2. The results showed good leaves growth period was 28th day with a composition 1: 1.
Kapasitas Tempat Pemrosesan Akhir (TPA) saat ini semakin berkurang, sehingga reduksi sampah perlu ditingkatkan. Sampah organik merupakan salah satu sampah yang banyak dihasilkan oleh aktivitas seharihari. Tujuan penelitian yakni mengetahui pengaruh waktu pengomposan dan komposisi kompos terhadap laju pertumbuhan daun tanaman Kacang Panjang (Vigna cylindrica (L.)). Metode yang digunakan untuk membuat kompos yaitu metode takakura. 80% komposisi kompos berasal dari sisa sayur bayam. Pembuatan kompos dilakukan dengan menambah mikro organisme local (MOL) dari buah dan kompos jadi untuk mempercepat sampah organik terdekomposisi. Variabel yang digunakan yaitu variasi waktu pengambilan kompos dan variasi komposisi kompos dengan tanah terhadap Kacang Panjang (Vigna cylindrica (L.)). Waktu pengambilan kompos ditentukan sebagai variabel penelitian dengan variasi pengambilan pada hari ke - 14, 28, dan 42, sedangkan variasi komposisi kompos dan tanah yang diujikan terhadap tanaman Kacang Panjang (Vigna cylindrica (L.)) sebesar 1 : 1 dan 1 : 2. Hasil penelitian menunjukkan laju pertumbuhan daun paling besar yaitu pada variasi waktu pengambilan kompos hari ke – 28 dengan komposisi 1 : 1.