bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnetotelluric evidence for the multi-microcontinental composition of eastern South China and its tectonic evolution
Authors: Kun Zhang , Qingtian Lü , Zhao Jinhua , Yan Jiayong , Hu Hao , Luo Fan , Fu Guangming , Tao Xin 
Published: August 2020

AbstractThe tectonic boundaries and geodynamic evolution of the South China Block are widely debated. While the community largely agrees on the occurrence of the collision between the Yangtze and Cathaysia Blocks, the lack of ultrahigh-pressure metamorphic rocks and obscurity of the boundary lead to inconsistencies among the abundant geological and geophysical data. We present three profiles that reveal the geoelectrical structure of eastern South China. Distinct conductive interfaces oriented NE–SW are identified in the geoelectrical lithosphere, which separate the region into six parts. To interpret our observations and resultant model, we develop and propose a mechanism of “microcontinent interaction”. Our new model justifies the prior proposed models of ‘block collision’ and additionally proposes ‘multi-terrane accretion-collision’ to address the tectonic evolution.
SNG and DNG meta-absorber with fractional absorption band for sensing application
Authors: Hoque Ahasanul , Islam Mohammad Tariqul , Almutairi Ali F. , Chowdhury Muhammad E. H. , Samsuzzaman Md. 
Published: August 2020

AbstractThis paper reports on a tunable transmission frequency characteristics-based metamaterial absorber of an X band sensing application with a fractional bandwidth. Tunable resonator metamaterial absorbers fabricated with dielectric surface have been the subject of growing attention of late. Absorbers possess electromagnetic properties and range modification capacity, and they have yet to be studied in detail. The proposed microstructure resonator inspired absorber with triple fractional band absorption consists of two balanced symmetrical vertical patches at the outer periphery and a tiny drop hole at two edges. Experimental verification depicted two absorption bands with single negative (SNG) characteristics for two resonances, but double negative (DNG) for single resonance frequency. The mechanism of sensing and absorption was analyzed using the transmission line principle with useful parameter analysis. Cotton, a hygroscopic fiber with moisture content, was chosen to characterize the proposed absorber for the X band application. The electrical properties of the cotton changed depending on the moisture absorption level. The simulation and the measured absorption approximately justified the result; the simulated absorption was above 90% (at 10.62, 11.64, and 12.8 GHz), although the steady level was 80%. The moisture content of the cotton (at different levels from 0 to 32.13%) was simulated, and the transmission resonance frequency changed its point in two significant ranges. However, comparing the two adopted measurement method and algorithm applied to the S parameter showed a closer variation between the two resonances (11.64 and 12.8 GHz) which signified that a much more accurate measurement of the cotton dielectric constant was possible up to a moisture content of 16.1%. However, certain unwanted changes were noted at 8.4–8.9 GHz and 10.6–12.4 GHz. The proposed triple-band absorber has potential applications in the X band sensing of moisture in capsules or tablet bottles.
QTL mapping and GWAS for field kernel water content and kernel dehydration rate before physiological maturity in maize
Authors: Li Shufang , Zhang Chunxiao , Lu Ming , Yang Deguang , Qian Yiliang , Yue Yaohai , Zhang Zhijun , Jin Fengxue , Wang Min , Liu Xueyan , Liu Wenguo , Li Xiaohui 
Published: August 2020

AbstractKernel water content (KWC) and kernel dehydration rate (KDR) are two main factors affecting maize seed quality and have a decisive influence on the mechanical harvest. It is of great importance to map and mine candidate genes related to KWCs and KDRs before physiological maturity in maize. 120 double-haploid (DH) lines constructed from Si287 with low KWC and JiA512 with high KWC were used as the mapping population. KWCs were measured every 5 days from 10 to 40 days after pollination, and KDRs were calculated. A total of 1702 SNP markers were used to construct a linkage map, with a total length of 1,309.02 cM and an average map distance of 0.77 cM. 10 quantitative trait loci (QTLs) and 27 quantitative trait nucleotides (QTNs) were detected by genome-wide composite interval mapping (GCIM) and multi-locus random-SNP-effect mixed linear model (mrMLM), respectively. One and two QTL hotspot regions were found on Chromosome 3 and 7, respectively. Analysis of the Gene Ontology showed that 2 GO terms of biological processes (BP) were significantly enriched (P ≤ 0.05) and 6 candidate genes were obtained. This study provides theoretical support for marker-assisted breeding of mechanical harvest variety in maize.
Solid acid catalyzed carboxymethylation of bio-derived alcohols: an efficient process for the synthesis of alkyl methyl carbonates
Authors: Kanakikodi Kempanna S. , Churipard Sathyapal R. , Halgeri A. B. , Maradur Sanjeev P. 
Published: August 2020

AbstractAcid catalyzed carboxymethylation of alcohols is an emerging organic transformation that has grabbed the attention of scientific community in recent years. In the present study, sulfonated mesoporous polymer (MP-SO3H) is presented as a highly active solid acid catalyst to convert a wide range of alcohols into alkyl methyl carbonates. The remarkable catalytic activity of MP-SO3H is comparable to that of reported homogeneous acid catalysts. A good correlation was established between the catalytic activity and textural properties of the material. An exceptional catalytic activity of MP-SO3H was observed for DMC mediated carboxymethylation of bio-derived alcohols which is unmatchable to conventional resins and zeolites. This superior activity of MP-SO3H is ascribed to its intrinsic mesoporosity, high acid strength and uniform coverage of surface area by active sites. The catalyst is recyclable, resistant towards leaching and can be used in successive runs without losing the original activity. To the best of our knowledge, MP-SO3H is the first solid acid catalyst to exemplify highest activity for the synthesis of different alkyl methyl carbonates using DMC. The protocol developed herein opens up new avenues to transform wide range of bio-alcohols into useful organic carbonates in the future.
Effects of l-theanine–caffeine combination on sustained attention and inhibitory control among children with ADHD: a proof-of-concept neuroimaging RCT
Authors: Kahathuduwa Chanaka N. , Wakefield Sarah , West Blake D. , Blume Jessica , Dassanayake Tharaka L. , Weerasinghe Vajira S. , Mastergeorge Ann 
Published: August 2020

AbstractWe examined the acute effects of l-theanine, caffeine and their combination on sustained attention, inhibitory control and overall cognition in boys with attention deficit hyperactivity disorder (ADHD). l-Theanine (2.5 mg/kg), caffeine (2.0 mg/kg), their combination and a placebo were administered in a randomized four-way repeated-measures crossover with washout, to five boys (8–15 years) with ADHD. Functional magnetic resonance imaging (fMRI) was performed during a Go/NoGo task and a Stop-signal task ~ 1 h post-dose. NIH Cognition Toolbox was administered ~ 2 h post-dose. Treatment vs. placebo effects were examined in multi-level mixed-effects models. l-Theanine improved total cognition composite in NIH Cognition Toolbox (p = 0.040) vs. placebo. Caffeine worsened and l-theanine had a trend of worsening inhibitory control (i.e. increased Stop-signal reaction time; p = 0.031 and p = 0.053 respectively). l-Theanine–caffeine combination improved total cognition composite (p = 0.041), d-prime in the Go/NoGo task (p = 0.033) and showed a trend of improvement of inhibitory control (p = 0.080). l-Theanine–caffeine combination was associated with decreased task-related reactivity of a brain network associated with mind wandering (i.e. default mode network). l-Theanine–caffeine combination may be a potential therapeutic option for ADHD-associated impairments in sustained attention, inhibitory control and overall cognitive performance.
Structure/activity virtual screening and in vitro testing of small molecule inhibitors of 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from gut methanogenic bacteria
Authors: Cuccioloni Massimiliano , Bonfili Laura , Cecarini Valentina , Cocchioni Filippo , Petrelli Dezemona , Crotti Elena , Zanchi Raffaella , Eleuteri Anna Maria , Angeletti Mauro 
Published: August 2020

AbstractVirtual screening techniques and in vitro binding/inhibitory assays were used to search within a set of more than 8,000 naturally occurring small ligands for candidate inhibitors of 8-hydroxy-5-deazaflavin:NADPH oxidoreductase (FNO) from Methanobrevibacter smithii, the enzyme that catalyses the bidirectional electron transfer between NADP+ and F420H2 during the intestinal production of CH4 from CO2. In silico screening using molecular docking classified the ligand-enzyme complexes in the range between − 4.9 and − 10.5 kcal/mol. Molecular flexibility, the number of H-bond acceptors and donors, the extent of hydrophobic interactions, and the exposure to the solvent were the major discriminants in determining the affinity of the ligands for FNO. In vitro studies on a group of these ligands selected from the most populated/representative clusters provided quantitative kinetic, equilibrium, and structural information on ligands’ behaviour, in optimal agreement with the predictive computational results.
Quantitative analysis of heparan sulfate using isotopically labeled calibrants
Authors: Wang Zhangjie , Arnold Katelyn , Xu Yongmei , Pagadala Vijayakanth , Su Guowei , Myatt Hannah , Linhardt Robert J. , Liu Jian 
Published: August 2020

AbstractHeparan sulfate is a sulfated polysaccharide that displays essential physiological functions. Here, we report a LC-MS/MS-based method for quantitatively determining the individual disaccharide composition and total amount of heparan sulfate. Using eight 13C-labeled disaccharide calibrants and one 13C-labeled polysaccharide calibrant, we complete the analysis in one-pot process. The method is both sensitive and has the throughput to analyze heparan sulfate from mouse tissues and plasma.
Programmed folding into spiro-multicyclic polymer topologies from linear and star-shaped chains
Authors: Mato Yoshinobu , Honda Kohei , Ree Brian J. , Tajima Kenji , Yamamoto Takuya , Deguchi Tetsuo , Isono Takuya , Satoh Toshifumi 
Published: August 2020

AbstractThe development of precise folding techniques for synthetic polymer chains that replicate the unique structures and functions of biopolymers has long been a key challenge. In particular, spiro-type (i.e., 8-, trefoil-, and quatrefoil-shaped) polymer topologies remain challenging due to their inherent structural complexity. Herein, we establish a folding strategy to produce spiro-type multicyclic polymers via intramolecular ring-opening metathesis oligomerization of the norbornenyl groups attached at predetermined positions along a synthetic polymer precursor. This strategy provides easy access to the desired spiro-type topological polymers with a controllable number of ring units and molecular weight while retaining narrow dispersity (Ɖ < 1.1). This effective strategy marks an advancement in the development of functionalized materials composed of specific three-dimensional nanostructures.
Suppressed anti-inflammatory heat shock response in high-risk COVID-19 patients: lessons from basic research (inclusive bats), light on conceivable therapies
Authors: Heck Thiago Gomes , Ludwig Mirna Stela , Frizzo Matias Nunes , Rasia-Filho Alberto Antonio , Homem de Bittencourt Paulo Ivo 
Published: August 2020

AbstractThe major risk factors to fatal outcome in COVID-19 patients, i.e., elderliness and pre-existing metabolic and cardiovascular diseases (CVD), share in common the characteristic of being chronic degenerative diseases of inflammatory nature associated with defective heat shock response (HSR). The molecular components of the HSR, the principal metabolic pathway leading to the physiological resolution of inflammation, is an anti-inflammatory biochemical pathway that involves molecular chaperones of the heat shock protein (HSP) family during homeostasis-threatening stressful situations (e.g., thermal, oxidative and metabolic stresses). The entry of SARS coronaviruses in target cells, on the other hand, aggravates the already-jeopardized HSR of this specific group of patients. In addition, cellular counterattack against virus involves interferon (IFN)-mediated inflammatory responses. Therefore, individuals with impaired HSR cannot resolve virus-induced inflammatory burst physiologically, being susceptible to exacerbated forms of inflammation, which leads to a fatal “cytokine storm”. Interestingly, some species of bats that are natural reservoirs of zoonotic viruses, including SARS-CoV-2, possess an IFN-based antiviral inflammatory response perpetually activated but do not show any sign of disease or cytokine storm. This is possible because bats present a constitutive HSR that is by far (hundreds of times) more intense and rapid than that of human, being associated with a high core temperature. Similarly in humans, fever is a physiological inducer of HSR while antipyretics, which block the initial phase of inflammation, impair the resolution phase of inflammation through the HSR. These findings offer a rationale for the reevaluation of patient care and fever reduction in SARS, including COVID-19.
Adaptation of a Caregiver-Implemented Naturalistic Communication Intervention for Spanish-Speaking Families of Mexican Immigrant Descent: A Promising Start
Authors: Cycyk Lauren M. , Moore Heather W. , De Anda Stephanie , Huerta Lidia , Méndez Shaundra , Patton Christina , Bourret Camille 
Published: August 2020

Purpose
Caregiver-implemented naturalistic communication interventions (CI-NCIs) support the communication abilities of young children with language disorders and enhance the communication behaviors of their caregivers. Yet, few CI-NCIs have been adapted and tested for feasibility with families who speak Spanish at home. This study addresses this gap in the literature by examining the social validity and preliminary outcomes of an adapted CI-NCI program with families who identified as Mexican immigrants and spoke Spanish.

Method
A multiphase cultural adaptation process enhanced the Language and Play Every Day program for Spanish-speaking Mexican immigrant families in the United States. Six families, including eight caregivers and eight toddlers, participated. Caregivers received coaching on the use of language-facilitating strategies within existing home routines. Multiple measures of the social validity of the intervention's goals, procedures, and outcomes were collected. Changes in caregivers' reported confidence, knowledge, and use of language-facilitating strategies and children's receptive and expressive communication were examined to determine preliminary outcomes.

Results
Overall, caregivers perceived many of the intervention's goals, procedures, and outcomes as socially valid and specified aspects of the intervention needing improvement. Caregivers and children showed modest but potentially clinically meaningful gains in their communication skills following the intervention despite wide individual variability.

Conclusions
Given some recommendations to further adapt the intervention, this CI-NCI appears to be feasible for supporting the communication development of children of Spanish-speaking Mexican immigrant descent. Thus, future research on the efficacy of the intervention is warranted.

Supplemental Material

https://doi.org/10.23641/asha.12269081
Beyond Scores: Using Converging Evidence to Determine Speech and Language Services Eligibility for Dual Language Learners
Authors: Castilla-Earls Anny , Bedore Lisa , Rojas Raúl , Fabiano-Smith Leah , Pruitt-Lord Sonja , Restrepo María Adelaida , Peña Elizabeth 
Published: August 2020

Purpose
Speech-language pathologists have both a professional and ethical responsibility to provide culturally competent services to dual language learners (DLLs). In this tutorial, we recommend that clinicians use a comprehensive assessment of converging evidence to make diagnostic decisions in DLLs in accordance with the American Speech-Language-Hearing Association's Code of Ethics. The content of this tutorial is most appropriate for Spanish–English DLLs between the ages of 4 and 8 years.

Method
We propose a converging evidence approach, in which one single method is not the deciding factor in making diagnostic decisions regarding the dual language and speech production skills of DLLs. Converging evidence refers to the idea that multiple pieces of assessment data must come together and trend in the same direction to make a diagnostic decision. We recommend gathering assessment data using a combination of language experience questionnaires, bilingual language sample analysis using large-scale reference databases, evaluation of learning potential, and standardized testing. These four assessment methods allow clinicians to examine the child in different contexts to determine their strengths and weakness in communication abilities.

Conclusion
We illustrate the converging evidence framework using two case studies to guide the clinician through the diagnostic decision-making process.
Vacuum ultraviolet photoabsorption spectroscopy of space-related ices: 1 keV electron irradiation of nitrogen- and oxygen-rich ices
Authors: Ioppolo S. , Kaňuchová Z. , James R. L. , Dawes A. , Jones N. C. , Hoffmann S. V. , Mason N. J. , Strazzulla G. 
Published: August 2020

Context. Molecular oxygen, nitrogen, and ozone have been detected on some satellites of Saturn and Jupiter, as well as on comets. They are also expected to be present in ice-grain mantles within star-forming regions. The continuous energetic processing of icy objects in the Solar System induces physical and chemical changes within the ice. Laboratory experiments that simulate energetic processing (ions, photons, and electrons) of ices are therefore essential for interpreting and directing future astronomical observations.
Aims. We provide vacuum ultraviolet (VUV) photoabsorption spectroscopic data of energetically processed nitrogen- and oxygen-rich ices that will help to identify absorption bands and/or spectral slopes observed on icy objects in the Solar System and on ice-grain mantles of the interstellar medium.
Methods. We present VUV photoabsorption spectra of frozen O2 and N2, a 1:1 mixture of both, and a new systematic set of pure and mixed nitrogen oxide ices. Spectra were obtained at 22 K before and after 1 keV electron bombardment of the ice sample. Ices were then annealed to higher temperatures to study their thermal evolution. In addition, Fourier-transform infrared spectroscopy was used as a secondary probe of molecular synthesis to better identify the physical and chemical processes at play.
Results. Our VUV data show that ozone and the azide radical (N3) are observed in our experiments after electron irradiation of pure O2 and N2 ices, respectively. Energetic processing of an O2:N2 = 1:1 ice mixture leads to the formation of ozone along with a series of nitrogen oxides. The electron irradiation of solid nitrogen oxides, pure and in mixtures, induces the formation of new species such as O2, N2, and other nitrogen oxides not present in the initial ice. Results are discussed here in light of their relevance to various astrophysical environments. Finally, we show that VUV spectra of solid NO2 and water can reproduce the observational VUV profile of the cold surface of Enceladus, Dione, and Rhea, strongly suggesting the presence of nitrogen oxides on the surface of the icy Saturn moons.
Chandra X-ray study confirms that the magnetic standard Ap star KQ Vel hosts a neutron star companion
Authors: Oskinova Lidia M. , Ignace Richard , Leto Paolo , Postnov Konstantin A. 
Published: August 2020

Context. KQ Vel is a peculiar A0p star with a strong surface magnetic field of about 7.5 kG. It has a slow rotational period of nearly 8 years. Bailey et al. (A&A, 575, A115) detected a binary companion of uncertain nature and suggested that it might be a neutron star or a black hole.
Aims. We analyze X-ray data obtained by the Chandra telescope to ascertain information about the stellar magnetic field and/or interaction between the star and its companion.
Methods. We confirm previous X-ray detections of KQ Vel with a relatively high X-ray luminosity of 2 × 1030 erg s−1. The X-ray spectra suggest the presence of hot gas at > 20 MK and, possibly, of a nonthermal component. The X-ray light curves are variable, but data with better quality are needed to determine a periodicity, if any.
Results. We interpret the X-ray spectra as a combination of two components: the nonthermal emission arising from the aurora on the A0p star, and the hot thermal plasma filling the extended shell that surrounds the “propelling” neutron star.
Conclusions. We explore various alternatives, but a hybrid model involving the stellar magnetosphere along with a hot shell around the propelling neutron star seems most plausible. We speculate that KQ Vel was originally a triple system and that the Ap star is a merger product. We conclude that KQ Vel is an intermediate-mass binary consisting of a strongly magnetic main-sequence star and a neutron star.
The Solar Orbiter mission
Authors: Müller D. , St. Cyr O. C. , Zouganelis I. , Gilbert H. R. , Marsden R. , Nieves-Chinchilla T. , Antonucci E. , Auchère F. , Berghmans D. , Horbury T. S. , Howard R. A. , Krucker S. , Maksimovic M. , Owen C. J. , Rochus P. , Rodriguez-Pacheco J. , Romoli M. , Solanki S. K. , Bruno R. , Carlsson M. , Fludra A. , Harra L. , Hassler D. M. , Livi S. , Louarn P. , Peter H. , Schühle U. , Teriaca L. , del Toro Iniesta J. C. , Wimmer-Schweingruber R. F. , Marsch E. , Velli M. , De Groof A. , Walsh A. , Williams D. 
Published: August 2020

Aims.Solar Orbiter, the first mission of ESA’s Cosmic Vision 2015–2025 programme and a mission of international collaboration between ESA and NASA, will explore the Sun and heliosphere from close up and out of the ecliptic plane. It was launched on 10 February 2020 04:03 UTC from Cape Canaveral and aims to address key questions of solar and heliospheric physics pertaining to how the Sun creates and controls the Heliosphere, and why solar activity changes with time. To answer these, the mission carries six remote-sensing instruments to observe the Sun and the solar corona, and four in-situ instruments to measure the solar wind, energetic particles, and electromagnetic fields. In this paper, we describe the science objectives of the mission, and how these will be addressed by the joint observations of the instruments onboard.Methods.The paper first summarises the mission-level science objectives, followed by an overview of the spacecraft and payload. We report the observables and performance figures of each instrument, as well as the trajectory design. This is followed by a summary of the science operations concept. The paper concludes with a more detailed description of the science objectives.Results.Solar Orbiter will combine in-situ measurements in the heliosphere with high-resolution remote-sensing observations of the Sun to address fundamental questions of solar and heliospheric physics. The performance of the Solar Orbiter payload meets the requirements derived from the mission’s science objectives. Its science return will be augmented further by coordinated observations with other space missions and ground-based observatories.