bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social Assistance for Poverty Reduction in the EU Countries: An Aspect of Socio-Economic Sustainability
Authors: Balvociute Rasa 
Published: February 2020

Abstract
Research on the impact of social assistance benefits and other socio-economic indicators on poverty reduction during 2000 – 2017 in 24 EU countries is presented in the paper. In order to assess the impact a regression analysis model of the panel data was composed by including such indicators as changes in gross total expenditure per capita, the GDP growth rate, the share of the retirement-age population, the unemployment rate of the working-age population, the long-term unemployment rate. Research findings revealed the main socio-economic indicators that have the greatest impact on changes in poverty. The economic slowdown reduced the at-risk-of poverty gap of people with the lowest income and the economic growth reduced the poverty gap with a lag of two periods (years). The overall impact of all social transfers under analysis on the at-risk-of poverty gap was insignificant. The at-risk-of poverty rate, which shows changes in the share of the most deprived population under analysis, increased when non-targeted and means-tested benefits gal geriau social transfers increased. On the basis of these findings it can be stated that, during the period under analysis, social assistance was not well-directed, i.e. did not focus on the most deprived part of the population.
Keywords: sustainable development, social assistance benefits, means-tested benefits, the at-risk-of-poverty rate, the relative poverty gap, panel data.
Az univerzális kvantor extra tág hatókör-értelmezése
Authors: Turi Gergő , Turi Gergő 
Published: February 2020

A hatókör-értelmezésre vonatkozó klasszikus generatív nézet szerint egy kvantor logikai hatóköre nem terjedhet túl azon a finit tagmondaton, amelyben az adott kvantor áll (azaz: nem vehet fel extra tág hatókört). Egyes, empirikusan ezidáig nem kellően megerősített feltételezések szerint azonban létezik egy kivételes, vonzat szerepű kötőmódú tagmondatot tartalmazó szerkezettípus, amely megengedi a benne szereplő univerzális kvantor számára az extra tág hatóköri olvasatot. Wurmbrand (2013; 2018) szintaktikai magyarázata szerint emiatt a kvantorhatókörre vonatkozó klasszikus, finit tagmondati lokalitási korlátot gyengíteni szükséges, míg Farkas–Giannakidou (1996) jelentéstani magyarázata azt állítja, hogy a kivételes hatóköri olvasat jelentéstani újraelemzésnek köszönhető.Tanulmányunkban a jelenséget magyar anyanyelvű felnőtt beszélők ítéletei alapján vizsgáljuk. Kimutatjuk, hogy az extra tág hatóköri értelmezés (1) valóban elérhető a kritikus mondattípusban, de (2) hasonlóképpen elérhető egy a kritikustól minimálisan eltérő olyan mondattípusban is, melyre magyarázatként csak a jelentéstani újraelemzés terjeszthető ki, míg a szintaktikai lokalitási korlát gyengítése nem. Ez alapján a vizsgált extra tág hatóköri olvasatnak a jelentéstani újraelemzésen alapuló magyarázata mellett, és a kvantorhatókör klasszikus, finit tagmondat alapú szintaktikai lokalitási megszorításának a feladása ellen érvelünk.
A hybrid approach development to solving the storage location assignment problem in a picker-to-parts system
Authors: Fontana Marcele Elisa , Nepomuceno Vilmar Santos , Garcez Thalles Vitelli 
Published: February 2020

Goal: This study developed a structured decision model capable of solving the storage location assignment problem (SLAP) in a picker-to-parts system, using multiples key performance indicators (KPIs).
Design / Methodology / Approach: A hybrid approach was developed. For that, a Multi-Objective Genetic Algorithm (MOGA) was used considering three fitness functions, but more functions may be considered. Through MOGA it was possible to verify a high number of solutions and reduce it into a Pareto frontier. After that, a Multiple-Criteria Decision-Making (MCDM) approach was used to choose the best solution.
Results: This model was able to find viable solutions considering multiples objectives, warehouse restrictions and decision makers’ preferences, and the required processing time for the simulated cases was insignificant.
Limitations of the investigation: One limitation of this work was the consideration of known and predictable data.
Practical implications: The proposed model was developed with the purpose of assisting companies that face this type of problem, providing a solution for SLAP requiring the minimum information and operational actions.
Originality / Value: SLAP is a NP (Non-Deterministic Polynomial time) complex problem and, after the MOGA, the number of solution can be still high for the final decision making by the engineering manager (decision maker - DM). Thus, the MOGA–MCDM hybrid approach developed was able incorporate the DM' preferences into a compensatory view, vetoing alternatives that were worse in any of the KPIs, to recommend a final solution.
Critical factors and Benefits in the use of Earned Value Management in construction
Authors: Netto Joaquim Teixeira , De Oliveira Nylvandir Liberato Fernandes , Freitas Andrey Pimentel Aleluia , Dos Santos João Alberto Neves 
Published: February 2020

Goal: The main objective of this study is to analyze the benefits and the critical success factors (CSF) to use of Earned Value Management (EVM) in the construction projects.
Design / Methodology / Approach: The research methodology was quantitative approach with statistical analysis of questionnaire with 106 answered and validated using the Cronbach's alpha and Kaiser-Meyer-Olkin.
Results: The construction companies identified the benefits and CSF in the use of EVM. The observed benefits were: achieving project cost, the definition of scope and schedule, anticipating project and project communication. The observed CSF were: team training, project management maturity, top management support, the need of pre-defined procedures, and the use of appropriate software.
Limitations of the investigation: The sample of research was composed exclusively of Brazilian construction managers.
Practical implications: Monitoring construction projects using EVM for construction companies.
Originality / Value: The EVM is widely used for project management. However, there are few studies on its use in the construction industry.
İSLAMİ ESASLARA UYGUN KRİPTO PARA ÖNERİSİ: İSLAMİ COİN (ISCOIN)
Authors: ÇETİN Abdurrahman 
Published: February 2020

Paranın geçmişi, takas ekonomisi, madeni para, kâğıt para, itibari para ve dijital para şeklinde tarihi bir seyir izlemiştir. Küresel likidite krizlerinin ardından artık doların rezerv para olma tekeline karşı tartışmalara başlanmış ve bu tartışmalar paralelinde 2009 yılından sonra Blok-zincir teknolojisinin yaygınlaşması Bitcoin, Etherium, Ripple ve Litcoin gibi kripto paraların finansal piyasalarda görülmesine ve yaygınlık kazanmasına yol açmıştır. Kripto paralara ilişkin önerilen alternatifler arasında petrole, yerel para birimlerine veya altına dayalı dijital para ihraçlarının iyi bir çözüm olabileceği ifade edilmektedir.
Küresel piyasalarda rezerv para birimi ve alternatif ödeme sistemleri arayışı devam ederken söz konusu gelişmeler İslami piyasalar açısından değerlendirilerek bu alanda bir çözüme ihtiyaç duyulduğu gözlenmiştir. Bu çalışmada tespit edilen ihtiyaca yönelik olarak mevcut önerilerin eksik yanlarını tamamlayarak, piyasalara güven telkin eden ve alternatif bir ödeme sistemi olarak geliştirilen “İslami Coin” (IsCoin) olarak isimlendirdiğimiz helal kripto para sisteminin nasıl tasarlanması gerektiği ele alınmaktadır.
It’s a mismatch! Overeducation and career mobility in Germany
Authors: Roller Christiane , Rulff Christian , Tamminga Michael M. 
Published: February 2020

Abstract
The career mobility model suggests that overeducated workers are more prone to take up on-the-job training, to climb up the career ladder, or to leave to professions more suitable to their educational level. Our empirical analysis, using the German SOEP, confirms this theory for Germany. Comparing adequately qualified and overqualified workers in jobs that require the same level of formal qualification indicates that overeducated workers have a higher probability to take up on-the-job training and have a higher probability to move to jobs that better match their educational level. Furthermore, we find that overeducated workers experience higher wage growth than their adequately educated colleagues.
Senecio serratuloides extract prevents the development of hypertension, oxidative stress and dyslipidemia in nitric oxide-deficient rats
Authors: Tata Charlotte Mungho , Sewani-Rusike Constance Rufaro , Oyedeji Opeopluwa Oyehan , Mahlakata Fikile , Shauli Mathulo , Nkeh-Chungag Benedicta Ngwenchi 
Published: February 2020

Abstract

Background
Hypertension is a silent killer with no obvious signs and symptoms; thus, it is crucial to prevent its development. Oxidative stress and hyperlipidemia are associated risk factors for developing hypertension. This study aimed at investigating the role of a crude extract of Senecio serratuloides in preventing the development of hypertension, oxidative stress and hyperlipidemia in a rat model of nitric oxide deficiency.

Methods
Female Wistar rats were co-treated with Nω-Nitro L-arginine methyl ester (L-NAME) (40 mg/kg) and the hydroethanolic extract of S. Serratuloides (HESS150 or HESS300 mg/kg) for 4 weeks. Twenty-hour urine samples were collected weekly during the study. At the end of the study serum, heart and kidneys were harvested for biochemical and histopathological analysis.

Results
The higher dose (300 mg/kg) of the extract was more effective in preventing increase in systolic (p<0.001) and diastolic (p<0.05) blood pressure. At the end of the treatment period HESS300 treated rats had significantly (p<0.01) higher concentration of creatinine (91.24 ± 6 mg/dL) in urine and significantly (6.36 ± 0.4 mg/24 h; 0.001) lower proteinuria compared to L-NAME control rats (55.75 ± 8 mg/dL and 18.92 ± 2 mg/24 h, respectively). Creatinine clearance and glomerular filtration rate were lower in the L-NAME control group compared to all treatment groups. HESS300 prevented L-NAME-induced decrease in serum angiotensin II concentration, significantly decreased malondialdehyde concentration in serum (p<0.05) and kidneys (p<0.001). It also significantly (p<0.001) decreased low-density lipoprotein concentration while increasing the concentration of high-density lipoprotein cholesterol. It showed cardio- and reno-protective effects and significantly (p<0.01) prevented collagen deposition in these target organs.

Conclusion
These findings demonstrate the potential of S. Serratuloides in protecting rats from developing hypertension, hyperlipidemia and oxidative stress.
The crystal structure of diaqua-bis(6-aminopicolinato-κ2
N,O)magnesium(II), C12H14O6N4Mg
Authors: Xi-Shi Tai , Xiao-Jing Zhou , Li-Li Liu , Shu-Hua Cao , Li-Hua Wang 
Published: February 2020

Abstract
C12H14O6N4Mg, monoclinic, P21/c (no. 14), a = 8.2501(10) Å, b = 12.7943(12) Å, c = 7.1562(7) Å, β = 113.912(13)°, V = 690.53(14) Å3, Z = 2, R
gt(F) = 0.0386, wR
ref(F
2) = 0.0921, T = 293(2) K.
On the left periphery of Spanish indirect interrogatives
Authors: García-Núñez José María 
Published: February 2020

AbstractSpanish doubly filled complementizer (DFComp) clauses differ from plain embedded questions in a number of respects (availability of discourse-related projections, islandhood, sequence of tenses, licensing of discourse particles). I argue that the contrast is caused by the presence in the left periphery of these clauses of an illocutionary projection (Haegeman 2004, 2006; Coniglio and Zegrean 2012; Woods 2016b) between the leftmost projection, here identified as Haegeman’s (2004) SubP, and the criterial interrogative projections (InterP and QembP). This illocutionary projection prevents syncretism of the clause-typing and the criterial projections, the default option in plain embedded clauses. This not only explains the range of structural phenomena differentiating DFComp clauses and embedded questions, but also a key semantic property of the former, namely their speech-act denotation. Finally, DFComp clauses are compared with plain embedded questions displaying root behavior under first-person matrix subjects and with English inverted embedded questions. Both are shown to pose minimal variants of the structural pattern proposed for DFComp clauses.
The correlation between methylenetetrahydrofolate reductase gene 677C > T polymorphism and fetal congenital defects: A meta-analysis
Authors: Li Dexia , Wang Enxia , Gao Xia , Li Ping 
Published: February 2020

Abstract

Objective To investigate the correlation between the methylenetetrahydrofolate reductase (MTHFR) gene 677C> T polymorphism and fetal congenital defects.

Method Original studies relevant to the MTHFR gene 677C>T single nucleotide polymorphism and fetal congenital defects were systematically searched in the electronic databases of Medline, EMBSE and China National Knowledge Infrastructure (CNKI). All relevant publications were screened for inclusion in the present work. The correlation between the MTHFR gene 677C > T single nucleotide polymorphism and the occurrence of fetal congenital defects was expressed as an odds ratio (OR) and its 95% confidence interval (95% CI). Publication bias was assessed by Begg’s funnel plot and Egger’s line regression test.

Results Nineteen case-control studies were ultimately included in the present meta-analysis. The pooled results indicated that the general risk of fetal congenital defects was significantly elevated in subjects with the 677T allele of the MTHFR gene in dominant (OR=1.07,95%CI:1.03-1.12, P<0.05), homozygous (OR=1.17,95%CI:1.06-1.30, P<0.05) and recessive genetic models (OR=1.16,95%CI:1.03-1.31, P<0.05) through the random effect method. However, significant publication bias was identified upon pooling the individual data and evaluating the correlation.

Conclusion According to the present evidence, the MTHFR gene 677C>T single nucleotide polymorphism is correlated with poor pregnancy outcomes, and subjects with the T allele have an increased risk of developing general fetal congenital defects.
Die Vielfalt der Beobachter Zum Zusammenhang von Kontingenz und Quantifizierung in der Beobachtung der Zukunft der Wirtschaft
Authors: Beyrle Judith 
Published: February 2020

ZusammenfassungDie Feststellung, dass die präzise Vorausschau der Wirtschaftsentwicklung nicht möglich ist, weil diese Entwicklung abhängig von ihrer Beobachtung ist und sich dadurch selbst mit in Rechnung stellen müsste, mündet bislang in der Empfehlung, reflexive und explizit orientierende Formen des Umgangs mit Prognosen zu wählen. Der vorliegende Aufsatz verschränkt die theoretischen Ausarbeitungen einer systemtheoretisch inspirierten Wirtschaftssoziologie mit der Beobachtung der Verwendung der Prognosevielfalt in Tageszeitungen und kommt daraufhin zu dem Schluss, dass die Zahlenförmigkeit der Prognosen Vergleiche eröffnet, welche die Perspektivität der Beobachtungen vergleichbar macht und somit relativiert.
Distinktion und Inklusion. Die Beobachtung von „Diversität“ im Recht
Authors: Bora Alfons 
Published: February 2020

ZusammenfassungRechtsprechung und Literatur lassen ein steigendes Interesse an Phänomenen der Diversität erkennen. Aus rechtssoziologischer Sicht greifen sie damit nicht nur einen Begriff aus der politischen Praxis auf, sondern verweisen auf ein tiefer liegendes Problem, das gewissermaßen bei der Entstehung der Rechtssoziologie Pate stand. Es betrifft den Umgang mit Multinormativität als Herausforderung für das Recht, vor allem aber auch für die rechtssoziologische Theorie. Ein sehr knapper Abriss der in der Rechtssoziologie vertretenen Lösungen führt zur Diskussion der systemtheoretischen Differenzierungstheorie. Auch sie, so das Ergebnis, wirft Anschlussfragen auf, etwa diejenige nach der Rolle hybrider Grenzorganisationen und deren Übersetzungsleistungen im Umgang mit Diversität.
Insatisfaccion por la imagen corporal y baja autoestima por la apariencia física en estudiantes de la facultad de medicina de la Universidad de los Andes del Estado Merida Venezuela
Authors: López Atencio Pedro , Prado P. José R. , Montilla Mercedes , Molina Viana Zarela , Da Silva Glenda , Arteaga Fanny 
Published: February 2020

La presente investigación tuvo como propósito central evaluar la insatisfacción por la imagen corporal y su relación con la baja autoestima por la apariencia física en estudiantes de la Facultad de Medicina de La Universidad de Los Andes en Mérida Venezuela. El estudio fue de tipo no experimental correlacional. La muestra estuvo constituida por 189 estudiantes, 27% masculino y 73% femenino, con una edad promedio de 19,58 años ±1,57 (varones 19,81 años ± 1,74 y para las mujeres 20,24 años ± 1,76). Los participantes fueron seleccionados de los cursos del primer año de las carreras de: Medicina, Enfermería y Nutrición, los cuales fueron seleccionados de forma intencional. El instrumento empleado para determinar la Insatisfacción por la Imagen Corporal fue el Body Shape Questionnaire (Cooper y Taylor, 1987). El método de Graffar Modificado fue utilizado para determinar el estrato socioeconómico de los participantes (Méndez y Méndez, 1994). A los datos se les aplicó el análisis descriptivo (frecuencia, porcentajes, media) e inferencial (ANOVA de un solo factor a través del paquete estadístico SPSS versión 9.0). Entre los principales hallazgos en el estudio se pudo determinar una asociación estadísticamente significativa entre la insatisfacción con la imagen corporal, la baja autoestima por la apariencia física con el género χ2 (2, N= 189) = 9,686, p=0,008. A través de ANOVA se pudo determinar que las diferencias en las medias para los niveles de insatisfacción y baja autoestima con la imagen corporal y el género son estadísticamente significativas, F=11,236; p=0,008, F=10,23; p=0,002 respectivamente. Conclusiones: los resultados obtenidos permiten sugerir sobre la relación que existe entre la insatisfacción y la baja autoestima por la apariencia física, existiendo un rechazo por la propia imagen corporal causada por la percepción distorsionada o no de la misma, lo que podría afectar la autoestima por la apariencia física.
Масові дослідження з використанням х-променів: перші кроки флюорографії
Authors: Кисільова Т. О. 
Published: February 2020

У статті розглянуто передумови та перші спроби використання в медичній практиці рентгенівського випромінювання для масових досліджень органів грудної клітини. Значний поштовх для розробки методу такої спрямованості надала епідемія туберкульозу, що виникла в Європі під час Першої світової війни. Побудування нової діагностичної методики передбачало в першу чергу суттєве зниження собівартості отримання однієї світлини. Розв’язанням висунутої проблеми вбачалося фотографування об’єктів з флуоресцентного екрана з використанням звичайного фотоапарата та малоформатної плівки. Створення цинк-кадмій- сульфідних екранів усунуло останню перешкоду на шляху становлення методу масового дослідження органів грудної порожнини – флюорографії.
У 1937 р. бразильський рентгенолог Мануель Діас де Абреу першим провів масове профілактичне флюорографічне дослідження легенів мешканців Ріо-де- Жанейро. Його успіх надихнув науковців різних країн на власні розробки. В СРСР перше повідомлення про створення вітчизняного флюорографа з’явилося в 1939 р. за авторством Я. Л. Шика. Також значний внесок у розробку методу внесли К. В. Помельцов, В. Ф. Купріянов, Я. Л. Шехтман, Н. Ф. Заркевич та інші. Завдяки розробці та впровадженню флюорографічних досліджень у країнах Європи та Америки вдалося зупинити розповсюдження епідемії туберкульозу легенів та надати своєчасну допомогу широким верствам населення. Економічна та діагностична цінність методу дозволяє його використання й в сучасній медичній практиці.
“Family Values Don’t Stop at the Rio Grande . . .”: Can the Republican Party Convert Hispanic Voters?
Authors: Davison Donald 
Published: February 2020

As the Hispanic community becomes increasingly important in American politics there are competing views about whether they can be converted to the Republican Party. One perspective argues that Hispanics’ religion and traditional social values makes them natural constituents of the Republican Party. Alternatively, Hispanics are primarily concerned about issues promoting their well-being and topics such as moral values or religion are private. We use a novel approach to test whether traditional social values might attract Hispanic voters to the Republican Party. Using exit poll results for ballot propositions on moral issues from Arizona, Colorado, and Florida we find weak evidence that traditional values will convert Hispanics to the Republican Party. Instead, our results indicate that traditional social values issues reinforce the polarization between the two parties.
Phase Ib Study of Crizotinib plus Pembrolizumab in Patients with Previously Untreated Advanced Non-Small Cell Lung Cancer with ALK Translocation
Authors: Patel Sandip Pravin , Pakkala Suchita , Pennell Nathan A. , Reckamp Karen L. , Lanzalone Silvana , Polli Anna , Tarazi Jamal , Robert-Vizcarrondo Francisco 
Published: February 2020

Abstract

Lessons Learned
This study evaluating first-line crizotinib plus pembrolizumab in patients with anaplastic lymphoma kinase (ALK)–positive advanced non-small cell lung cancer (NSCLC) was terminated early because increased availability of second-generation ALK inhibitors resulted in difficulty identifying and accruing eligible patients. In the small number of patients enrolled, elevated transaminases were the most common treatment-related toxicity. No other relevant toxicities were observed. Although no definitive conclusions could be drawn because of the small number of patients studied, the higher frequency of severe transaminase increases noted in this sample should be of concern if ALK inhibitor and PD-L1/PD-1 inhibitor combinations are tested in future studies.

Background
Previous research suggests single-agent crizotinib is efficacious for the treatment of anaplastic lymphoma kinase (ALK)–rearranged advanced non-small cell lung cancer (NSCLC).

Methods
This study evaluated the safety and preliminary antitumor activity of crizotinib plus pembrolizumab as first-line therapy in patients with ALK-rearranged NSCLC. Patients were initially treated at dose level 0 (DL0) with crizotinib 250 mg twice daily and pembrolizumab 200 mg every 3 weeks (cycle duration was 3 weeks). If a dose-limiting toxicity occurred, subsequent patients were enrolled at a lower dose level (dose level −1 [DL−1]: 3 weeks of crizotinib monotherapy 250 mg twice daily, followed by crizotinib 250 mg twice daily with the addition of pembrolizumab 200 mg every 3 weeks). The primary endpoint was dose-limiting toxicity. Antitumor activity was assessed.

Results
Nine patients were enrolled: two at DL0, then seven at DL−1. Dose-limiting toxicities occurred in four patients (grade 3 increases in alanine aminotransferase [ALT] and aspartate aminotransferase [AST] and grade 3 fatigue at DL0; grade 3 increase in ALT and grade 3 increases in both ALT and AST at DL−1).

Conclusion
The maximum tolerated dose was not determined because slow accrual resulted in early study termination.