bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cytokine and inflammatory mediators are associated with cytotoxic, anti-inflammatory and apoptotic activity of honeybee venom
Authors: Salama Mohamed A. , Younis Mohamed A. , Talaat Roba M. 
Published: June 2020

Abstract

Objective
The present study aimed to evaluate cytotoxic, apoptotic, and anti-inflammatory properties of bee venom (BV) as well as changes in cytokine secretion levels and nitric oxide (NO) production using three different cancer cell lines [liver (Hep-G2), breast (MCF-7), and cervical (HPV-18 infected HeLa cells)] and two normal cells (splenocytes and macrophages (MQ).

Methods
Cytotoxic activity of BV against tumor cell lines and normal splenocytes/MQ was tested by MTT assay. By ELISA (ELISA); Tumor necrosis factor (TNF-α), Interleukine (IL-10) and interferon (IFN-γ) were measured. Caspase three expressions was evaluated using reverse transcription-polymerase chain reaction (RT-PCR). Nitric oxide (NO) was estimated using a colorimetric assay.

Results
BV has a significant cytotoxic effect on all cell lines in a dose- and time-dependent manner; none of them was toxic for normal cells. Treating Hep-G2 cells with BV showed a reduction in IL-10, elevation in TNF-α with no change in IFN-γ level. MCF-7 cells have low IL-10 and TNF-α and high IFN-γ production level. Elevation of IL-10 and IFN-γ coincides with a reduction in TNF-α level was demonstrated in HeLa cells. The expression of Caspase three was dramatically increased with elevation in BV concentration in all tested cancer cell lines. A gradual decrease in NO production by MQ with increasing BV dose was observed.

Conclusion
Taken together, our results stressed on the importance of BV as a potent anti-tumor agent against various types of cancers (Liver, Breast, and Cervix). Further steps towards the use of BV for pharmacological purposes must be done.
Jenseits des Dualismus zwischen tierischer Natur und geistiger Natur: Kants Mensch „in zwiefacher Qualität“ und Schillers „ganzer Mensch“
Authors: Falduto Antonino 
Published: June 2020

AbstractIn my contribution, I discuss the important role of moral anthropological questions in the development of Schiller’s theoretical thought. I underline the fact that Schiller’s philosophical questions in Jena are much closer to those he confronted in Stuttgart – much closer than is considered to be the case in contemporary Schiller scholarship. I show how this continuity becomes evident when we take into consideration the moral anthropological topics that continued to interest Schiller throughout his life. To ground my argument, I show that the concept of the“whole human being” (i. e. the concept of a human considered in its entirety, as both sensible and rational) constitutes the continuous characteristic of Schiller’s philosophical considerations.
On Dem. 24.20–23 and the So-Called ἐπιχειροτονία τῶν νόμων:Some Final Clarifications in Response to M. H. Hansen
Authors: Canevaro Mirko 
Published: June 2020

SummaryThis short article goes back to the problem of the authenticity of the document found at Dem. 24.20–23, with wide implications for the reconstruction of Atheniannomothesia. Without providing a comprehensive response to M. H. Hansen’s recent KLIO article on the topic (M. H. Hansen, The Inserted Document at Dem. 24.20–23. Response to Mirko Canevaro, KLIO 101, 2019, 452–472; itself a response to a previous KLIO article by M. Canevaro), it clarifies some key issues and clears up some important misunderstandings, also providing new evidence against the authenticity of the document.
À propos du début du décret d’Aigai en l’honneur du roi Séleucos I et d’Antiochos I
Authors: Caneva Stefano G. 
Published: June 2020

RésuméCet article offre une nouvelle lecture et interprétation des premières lignes préservées du décret issu par la cité éolique d’Aigai en l’honneur du roi Séleucos I et de son fils Antiochos, à la suite de la bataille de Kouroupédion. Le commentaire se focalise sur le rapport entre la syntaxe et le message du texte, sur l’utilisation de la dénominationsôteres, entre nom commun et épiclèse cultuelle, ainsi que sur la manière de laquelle les citoyens d’Aigai ont justifié l’octroi des plus grands honneurs cultuels, par lesquels leurs bienfaiteurs sont adressés en qualité de divinités qui se sont manifestées.
Subsidia dominationi:The Early Careers of Tiberius Claudius Nero and Nero Claudius Drusus Revisited
Authors: Vervaet Frederik Juliaan 
Published: June 2020

SummaryWhereas many aspects of the Augustan age continue to enjoy ongoing or renewed interest, the early careers of Tiberius Claudius Nero (born 16 November 42 BCE) and Nero Claudius Drusus (March/April 38 BCE), Livia’s sons from her marriage to Ti. Claudius Nero (pr.42), have not been subject to much discussion or controversy of late. On the one hand, this could, perhaps, be explained in that they were quite young during the formative stages of the so-called Augustan monarchy, the critical settlements being those of 27, 23 and 19 BCE, the eye-catchers par excellence in the political history of the early Augustan era. On the other hand, Livia’s sons only really emerge into the spotlight of both ancient sources and modern scholarship after the untimely passing of M. Vipsanius Agrippa in 12 BCE. This paper aims at revisiting the evidence for Tiberius’ and Drusus’ careers in the decade or so before the latter’s premature death in Germany in 9 BCE, the period preceding the rapid rise (and demise) of Gaius and Lucius Caesar. There are, indeed, strong indications that Livia’s sons played a far more important part than has hitherto been recognized, both in terms of their official position and their role in assisting Augustus with one of his most important political objectives, namely the imperial monopolization of the public triumph.
On split involutive regular BiHom-Lie superalgebras
Authors: Guo Shuangjian , Zhang Xiaohui , Wang Shengxiang 
Published: June 2020

Abstract
The goal of this paper is to examine the structure of split involutive regular BiHom-Lie superalgebras, which can be viewed as the natural generalization of split involutive regular Hom-Lie algebras and split regular BiHom-Lie superalgebras. By developing techniques of connections of roots for this kind of algebras, we show that such a split involutive regular BiHom-Lie superalgebra

L

{\mathfrak{L}}

is of the form

L
=
U
+

∑
α

I

α

{\mathfrak{L}}=U+{\sum }_{\alpha }{I}_{\alpha }

with U a subspace of a maximal abelian subalgebra H and any I

α
, a well-described ideal of

L

{\mathfrak{L}}

, satisfying [I

α
, I

β
] = 0 if [α] ≠ [β]. In the case of

L

{\mathfrak{L}}

being of maximal length, the simplicity of

L

{\mathfrak{L}}

is also characterized in terms of connections of roots.
On a predator-prey system interaction under fluctuating water level with nonselective harvesting
Authors: Zhang Na , Kao Yonggui , Chen Fengde , Xie Binfeng , Li Shiyu 
Published: June 2020

Abstract
A predator-prey model interaction under fluctuating water level with non-selective harvesting is proposed and studied in this paper. Sufficient conditions for the permanence of two populations and the extinction of predator population are provided. The non-negative equilibrium points are given, and their stability is studied by using the Jacobian matrix. By constructing a suitable Lyapunov function, sufficient conditions that ensure the global stability of the positive equilibrium are obtained. The bionomic equilibrium and the optimal harvesting policy are also presented. Numerical simulations are carried out to show the feasibility of the main results.
On the N-spectrum of oriented graphs
Authors: Abudayah Mohammad , Alomari Omar , Sander Torsten 
Published: June 2020

Abstract
Given any digraph D, its non-negative spectrum (or N-spectrum, shortly) consists of the eigenvalues of the matrix AA

T
, where A is the adjacency matrix of D. In this study, we relate the classical spectrum of undirected graphs to the N-spectrum of their oriented counterparts, permitting us to derive spectral bounds. Moreover, we study the spectral effects caused by certain modifications of a given digraph.
Identification of key microRNAs of plasma extracellular vesicles and their diagnostic and prognostic significance in melanoma
Authors: Xiong Jiachao , Xue Yan , Xia Yu , Zhao Jiayi , Wang Yuchong 
Published: June 2020

Abstract
Melanoma is one of the most highly metastatic, aggressive and fatal malignant tumors in skin cancer. This study employs bioinformatics to identify key microRNAs and target genes (TGs) of plasma extracellular vesicles (pEVs) and their diagnostic and prognostic significance in melanoma. The gene expression microarray dataset (GSE100508) was downloaded from the Gene Expression Omnibus database. Differential analysis of miRNAs in pEVs was performed to compare melanoma samples and healthy samples. Then, TGs of the differential miRNAs (DE-miRNAs) in melanoma were selected, and differential genes were analyzed by bioinformatics (including Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment, protein–protein interaction network and prognostic analysis). A total of 55 DE-miRNAs were found, and 3,083 and 1,351 candidate TGs were diagnostically correlated with the top ten upregulated DE-miRNAs and all downregulated DE-miRNAs, respectively. Prognostic analysis results showed that high expression levels of hsa-miR-550a-3p, CDK2 and POLR2A and low expression levels of hsa-miR-150-5p in melanoma patients were associated with significantly reduced overall survival. In conclusion, bioinformatics analysis identified key miRNAs and TGs in pEVs of melanoma, which may represent potential biomarkers for the early diagnosis and treatment of this cancer.
Wide gamut, angle-insensitive structural colors based on deep-subwavelength bilayer media
Authors: Pan Hui , Wen Zhengji , Tang Zhihong , Xu Gangyi , Pan Xiaohang , Xu Qianqian , Lu Yue , Xu Hao , Sun Yan , Dai Ning , Hao Jiaming 
Published: June 2020

Abstract
Wide gamut and angle-insensitive structural colors are highly desirable for many applications. Herein, a new type of lithography-free, planar bilayer nanostructures for generating structural colors is presented, which is basically composed of a deep-subwavelength, highly absorbing dielectric layer on an opaque metallic substrate. Experimental results show that a galaxy of brilliant structural colors can be generated by our structures, and which can cover ∼50% of the standard red–green–blue color space by adjusting the nanostructure dimensions. The color appearances are robust with respect to the angle of vision. Theoretical partial reflected wave analyses reveal that the structural color effect is attributed to the strong optical asymmetric Fabry–Perot-type (F–P-type) thin-film resonance interference. The versatility of the structural color properties as well as the simplicity of their fabrication processes make this bilayer structures very promising for various applications, such as security marking, information encryption, and color display, etc.
Feasibility of removal S−2from Kraft black liquor recovery cycle with synthetic adsorbents (Cu-PAC and Cu-GAC)
Authors: Mollaei Masoume , Moeinaddini Mazaher , Khorasani Nematollah , Azadfallah Mohammad , Hemmasi Amirhooman 
Published: June 2020

AbstractSulfide ions (S−2) derived from Na2S in black liquor, after the pulping process, is the source of production H2S during of black liquor recovery cycle in Kraft pulp and paper industries. Tow adsorbents (Cu-PAC, Cu-GAC) by loading Cu+2on powder activated carbon (PAC) and granular activated carbon (GAC) were synthesized to created more adsorption sites and were improved their selectivity for removing S−2from black liquor with 3 level of sulfidity (18, 20 and 22 %). The adsorbents were characterized by BET, FTIR, SEM, and EDX. Adsorption of S−2for Cu-PAC and Cu-GAC were fitted well with Freundlich and Langmuir isotherm model respectively and both of the adsorbents followed pseudo-second-order kinetic. The results of thermodynamic parameters showed the endothermic process. The removal efficiency results showed Cu-PAC has better performance than Cu-GAC. This is due to the higher specific surface area of Cu-PAC, which has led to more adsorption sites for S−2. By considering appropriate temperature conditions and direct effect of the S−2on the production of H2S during of black liquor recovery cycle, Cu-PAC will be able to prevent H2S production and odorous the black liquor recovery cycle by removing 79.89 % of the S−2.
„Denn sie wissen nicht, was sie tun“ – Irrtum und moralische Zurechnung in Peter Abaelards Ethica – scito te ipsum
Authors: Gerlach Stefan 
Published: June 2020

Zusammenfassung
In diesem Artikel soll Peter Abaelards (1079–1142) Moralphilosophie vorgestellt werden, wie er sie in seiner Schrift Ethica – scito te ipsum (ca. 1139) entworfen hat. Besonderheit dieser Ethik ist es, dass Abaelard ausschließlich die Absicht einer Handlung als Gegenstand der moralischen Beurteilung zulässt. Von dieser sehr fortschrittlichen Position aus stellt sich allerdings die Frage, wie nach Abaelard der Fall zu behandeln ist, bei dem jemand einem Irrtum unterliegt, wie dies der Fall bei den Peinigern Jesu zu sein scheint, um deren Vergebung Jesus nach Lk 23 bittet. Ein Vergleich mit der Irrtumslehre des modernen Strafrechts zeigt die Aktualität und Grenzen des Ansatzes Abaelards.
Die ethische Pascaline
Authors: Schmidt Jochen 
Published: June 2020

Zusammenfassung
Die „ethische Pascaline“ ist ein Kunstwort, gemeint ist ein Modell der Arbeit theologischer Ethik, das von mechanistischen Annahmen geleitet ist, v. a. von der Annahme, dass die praktischen Widerstände, auf die die Arbeit der Ethik stößt, keine maßgeblichen Rückwirkungen auf die Bestimmung der Aufgabe und des Wesens der theologischen Ethik haben. Im Gegenüber zu einer solchen Konzeptualisierung werden Konturen einer hermeneutischen Ethik gezeichnet. Hermeneutische Ethik legt den Fokus auf das Prozesshafte aller ethischen Arbeit, auf unabschließbare Vorgänge der Erschließung von christlicher Tradition und ethischer Übung. Hermeneutische Ethik ist keine exklusive Alternative zu analytischer, „pascalinesquer“ Ethik, wohl aber eine notwendige Supplementierung, der deutlich mehr Aufmerksamkeit zuteilwerden sollte, als es bisher der Fall ist.
English comparative correlative constructions: A usage-based account
Authors: Hoffmann Thomas , Brunner Thomas , Horsch Jakob 
Published: June 2020

AbstractEnglish Comparative Correlatives (CCs) consist of two clauses, C1 and C2:[The more we get together,]C1[the happier we’ll be.]C2Recently, large corpus studies based on the Corpus of Contemporary American English have unearthed various meso-constructions in English CCs using covarying–collexeme analysis. The present study tests these findings against data from the British National Corpus (BNC), aiming to replicate previous results against data from another standard variety of English (British English) and a corpus that is sampled from a wider range of registers. Over 2,000 CC tokens from the BNC were analyzed with regard to hypotactic features, filler types encountered as comparative elements, and deletion phenomena. Moreover, in contrast to earlier corpus studies (such as Hoffmann, Thomas, Jakob Horsch, and Thomas Brunner. 2019. “The more data, the better: a usage-based account of the English comparative correlative construction.” Cognitive Linguistics30(1): 1–36), the present study also investigates the frequency of the semantically related C2C1 construction (You will be the happierC2,the more we get togetherC1) that previously has been found to be considerably less frequent than its counterpart. The results of the present analysis confirm that English CCs possess more paratactic than hypotactic features and, supporting most of the findings of Hoffmann, Horsch, and Brunner (2019) provide even stronger evidence for the existence of several symmetric meso-constructions.
Gaussons: optical solitons with log-law nonlinearity by Laplace–Adomian decomposition method
Authors: González-Gaxiola O. , Biswas Anjan , Alzahrani Abdullah Kamis 
Published: June 2020

AbstractThis paper presents optical Gaussons by the aid of the Laplace–Adomian decomposition scheme. The numerical simulations are presented both in the presence and in the absence of the detuning term. The error analyses of the scheme are also displayed.
Dynamics between the budget deficit and the government debt in the United States: a nonlinear analysis
Authors: Ahmed Haydory Akbar 
Published: June 2020

AbstractThis paper empirically investigates the dynamics between budget deficit and government debt in the U.S. using two different measures of the budget deficit: the current budget deficit and cyclically-adjusted budget deficit. A threshold Vector autoregression (VAR) model is estimated to explore the dynamics in different regimes using quarterly data from 1947:Q1 to 2017:Q3. The specification test rejects a linear VAR model against the threshold VAR. When we use the current budget deficit, regime 1 resemble governments prioritize minimizing budget deficit and debt, whereas, regime 2 resemble otherwise. When we use the cyclically adjusted budget deficit, regime 1 resemble economic expansions, whereas, regime 2 resemble recessions. The impulse responses show evidence of asymmetry and counter-cyclicality. The impulse responses also indicate that an increase in the debt dictate the government’s response towards minimizing the budget deficit and tend to prioritize budget deficit less when the economy expands.
Is Josephus Among The Qumranites? Unraveling A Textual Conundrum In 1 Samuel 10:27b
Authors: Glover Daniel B. 
Published: June 2020

AbstractAlthough Josephus’s biblical works typically reflect a dependence on the LXX, his text of Samuel presents a curious case to Hebrew Bible textual critics. One conundrum is found in 1Sam 10:27b, which includes material not found in the LXX or the MT. The presence of the same plus in 4QSama complicates the textual discussion. Some scholars take its presence in Josephus and 4QSama as evidence that the plus was omitted accidentally by the LXX and MT. While I broadly agree with their conclusions, this paper complicates their arguments and provides a more compelling reason for the omission of this material in the LXX and MT. The paper concludes by recognizing the value that the biblical text preserved in Josephus’s works brings to Hebrew Bible textual criticism.
1QSamuel–A Pre-canonical Shorter Recension of 2Samuel
Authors: Elgvin Torleif 
Published: June 2020

Abstract1QSamuel preserves a shorter ending of 2Samuel. Of the eight appendices attached to 2Samuel (20:23–24:25), the scroll contained either three or five, dependent on the (reconstructed) height of the columns. The scroll definitively omits the story of the census, a post-Chronicles insertion into 2Samuel. Also 21:1–14 and 23:1–7 are texts from the Hellenistic period. A comparison of 2Sam 21:1–14 and 1Sam 22:6–23 (the killing of the priests of Nob) suggests a late date also for the latter text, a dating supported by a suggested archaeological identification for the site of Nob.
Hebrewכֶּתֶרand Greek κίταρις: Revisiting the Persian Hypothesis
Authors: Thambyrajah Jonathan 
Published: June 2020

AbstractAlthough scholars had assumed that the lexemes כֶּתֶר in Hebrew and κίταρις in Greek derived from an Iranian source. More recently it has been argued by Salvesen that the word is genuinely Semitic. In this article, I revisit the older view.
Structural, electric and dielectric properties of perovskite based nanoparticles for energy applications
Authors: Nazir Arif , Khalid Fraz , Rehman Shafiq ur , Sarwar Masood , Iqbal Munawar , Yaseen Muhammad , Iftikhar Khan Muhammad , Abbas Mazhar 
Published: June 2020

Abstract
A nanocomposite electrode, obtained by combining two high performance perovskite materials, such as lanthanum strontium cobalt ferrite, La0.6Sr0.4Co0.2Fe0.8O3−δ (LSCF) and gadolinium doped ceria, Ce0.85Gd0.15O1.5 (GDC), were investigated as a promising cathode for moderate temperature solid oxide fuel cells (SOFCs). The synthesized material has good conductivity and catalytic performance. The purpose of this synthesis was to prepare a stable and highly performing nanocomposite cathode material. In this research work, LSCF and GDC were separately synthesized by co-precipitation and solid-state reaction method to gain a homogeneous perovskite phase. Varying concentrations of LSCF–GDC composite with GDC (10 wt.%, 20 wt.% and 30 wt.%) were synthesized followed by calcination at 600 °C to remove water content and to achieve an adequate porous structure for oxygen absorption and desorption. These fabricated LSCF, GDC, and the nanocomposite specimens were characterized for microstructure, particle size etc. via. X-ray diffraction method (XRD), scanning electron microscope (SEM) and the laser particle size analyzer. This procedural approach helps to expand new methods for generating bi-functional duel nano-sized perovskites with great performance and stability which can be utilized for advancement of renewable energy sectors especially for rechargeable fuel batteries.
Analytical evaluation of moments of collision-induced scattering with Lennard-Jones (2n-n) potential
Authors: Somuncu Elif , Gokbulut Melek 
Published: June 2020

Abstract
In this work, an analytic expression for the moment of the collision-induced scattering with Lennard-Jones (2n-n) potential, defining the collision induced polarizability of molecules, is presented. It has been demonstrated that this expression gives accurate results for various values of parameters. The proposed analytical formula has been confirmed through comparisons with the results literature. Because of its computational efficiency, the suggested formula is found utility in the collision-induced polarizability in the molecular system. To our knowledge, this paper presents the first approach to the evaluation of the first two moments for collision-induced scattering of molecules by Lennard-Jones (2n-n) potential. The results obtained for the moment of collision-induced scattering for values n = 6 is in good agreement with literature.
Approaching black-box calculations of pump-probe fragmentation dynamics of polyatomic molecules
Authors: Tikhonov Denis S. , Datta Amlan , Chopra Pragya , Steber Amanda L. , Manschwetus Bastian , Schnell Melanie 
Published: June 2020

Abstract
A general framework for the simulation of ultrafast pump-probe time resolved experiments based on Born-Oppenheimer molecular dynamics (BOMD) is presented. Interaction of the molecular species with a laser is treated by a simple maximum entropy distribution of the excited state occupancies. The latter decay of the electronic excitation into the vibrations is based on an on-the-fly estimation of the rate of the internal conversion, while the energy is distributed in a thermostat-like fashion. The approach was tested by reproducing the results of previous femtosecond studies on ethylene, naphthalene and new results for phenanthrene.