bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perception of abortion and associated female rights: use of behavior change communication strategies
Authors: Sheikh Naheed Humayun , Humayun Ayesha , Qureshi Mamoon Akbar , Zaman Shakila 
Published: March 2020

Abstract
Background: Developing and delivering tailored, context-specific messages could be beneficial, if delivered through acceptable and feasible channels of communication. Change in abortion-related behavior, being a sensitive and ethical issue, is difficult in developing countries like Pakistan. This study was conducted to change perceptions about abortion and associated female rights through behavior change communication strategies using religion-based elements in female attendees of Basic Health Units of District Lahore, Pakistan. Method: An Interventional study with Quasi-experimental design was carried out at basic health units (BHUs) of District Lahore, Pakistan during 2011-12. Total 100 eligible females were included in the study after taking written informed consent. 10 out of 37 BHUs were randomly selected for imparting religion-based, tailored messages using behavior change communication (BCC) strategies. 10 females at each BHU were conveniently recruited. Knowledge and perceptions about abortion and abortion-associated rights was assessed specifically on fate of unwanted pregnancy, decision-making, health seeking, health utilization, informed choices for prevention of abortion, abortion rights and fetal rights. Knowledge and perceptions before and after BCC were assessed to measure change on a structured, self-constructed, interviewer-administered questionnaire (local language). Data was analyzed in SPSS Version 20. Results: Mean age of 100 participants was 28.15+ 5.35 SD. 72.0 % females were between 21-30 years of age. Pre-BCC and post-BCC knowledge and perceptions were significantly different in what should be the fate of unwanted pregnancy, female should take decision about the fate of unwanted pregnancy, female has a right to decide about fate of unwanted pregnancy, why female should or should not decide about fate of unwanted pregnancy, female’s rights about seeking services of skilled personnel for delivery & termination of pregnancy, why female should or should not decide for seeking advice from skilled person for delivery & termination of pregnancy and decision about selecting place of delivery. The present study revealed that the intervention brought an observable percent point change in knowledge from 7.5% to more than 5 times. Conclusion: Specifically designed, tailored and contextualized messages using behavior change communication strategies can bring a significant improvement in abortion-related knowledge and perceptions of females.
Fertility Intentions and Effective Factors at a Glance: A Systematic Review
Authors: hashemzadeh mozhgan , shariati mohammad , Nazari Ali Mohammad , keramat afsaneh 
Published: March 2020

Abstract
Background: Persistence of low fertility in many countries has been a research concern during the last two decades. Childbearing decision-making is a complex process, involving many social, economic, political, and personal factors. We aim to provide comprehensive information about the core determinants of fertility intentions Methods: Ovid, MEDLINE, EMBASE, PsycINFO, CINAHL, Web of Science, SCOPUS, and GOOGLE SCHOLAR was searched for the relevant articles published from 1946 to December 2017. The current systematic review included the original and quantitative longitudinal and cross-sectional studies in English, The subjects of the studies were men and/or women in reproductive age (men aged 18-55 and women aged 18-45). Family planning methods were available in the reference country. Studies with less than 200 participants were excluded. Results: 45 Studies included in the qualitative synthesis.310727 participants included in the analysis. All effective factors in childbearing decision- making were classified into three main categories: Individual factors, Couple Puzzle, and Contextual factors. Factors such as age, religion, education, employment, and economic conditions were classified as individual factors. We also had a special focus on couples. As fertility is a dyadic process, for more emphasis we explained the couple relationship in case of the couple puzzle. Partnership Status, Gender Role Attitudes, Couple Desire, and Partnership Quality are the main aspects of couples puzzle Social network support (interaction within networks of family and friends) and family support environment are associated with childbearing intentions among couples. Conclusion: Further collaborative efforts by researchers and funding agencies will enable us to reveal fundamental mechanisms that affect and control fertility choices at different levels. As there are limited instances of interdisciplinary studies, studying fertility would highly benefit by crossing disciplinary and geographic boundaries. Although native scholars conduct fertility investigations in each country, the majority of research on fertility does not often communicate with one another.
The mechanistic investigation on hydrogen donation performance of bio-acids over bi-functional carbon nanotube catalysts
Authors: Zhang Jiajun , Zhang Xiaolei , Shen Dekui 
Published: March 2020

Abstract
Background Bio-acids such as acetic acid (AcOH) and formic acid (FA) are typical bio-oil compounds and platform chemicals that sourced from biomass pyrolysis. They are attracting global research attention due to their low-cost and safety merits with additional potentials as alternative in-situ hydrogen donors for bio-oil upgrading. However, the hydrogen donation performance of bio-acids have not been sufficiently evaluated, especially, investigation on high efficient catalysts to promote the process is lacking. In this study, novel catalysts of metal supported on nitrogen doped carbon nanotubes (CNTs) were thoroughly evaluated in facilitating the decomposition of both FA and AcOH for hydrogen donation by comparing ten different metal loadings and six types of CNT based substrates. Results It was found that Mo loading enabled the strongest binding energy to the bio-acid molecule among the ten evaluated transition metals, and Np (pyridinic nitrogen doped)-CNT led to bigger adsorption energy of AcOH than other substrates, e.g. Ng (graphitic nitrogen doped)-CNT or non-doped CNT. The new designed catalyst, Mo/N-CNTs, considerably facilitated the bio-acids decomposition by lowering the energy barriers, compared to the non-catalytic scenario. The favourable hydrogen donation pathways for AcOH are: CH3COOH→CH3CO→CH3→CH2→CH→C over Mo/Np-CNT, and CH3COOH→CH3CO→CH3C→CH3→CH2→CH1→C over Mo/Ng-CNT. The pathways for FA are: HCOOH→H+CO+OH over Mo/Np-CNT and HCOOH→HCO+OH over Mo/Ng-CNT. FA has showed the superiority for hydrogen donation than AcOH over Mo/N-CNT catalysts since it can be cleaved into hydroxyl group and hydrogen without an energy barrier, which will facilitate the following hydrogen donation from hydroxyl. Conclusions It was concluded that the new explored catalyst, Mo/N-CNTs, significantly lowered the decomposition energy barriers for both AcOH and FA thus promoting the hydrogen donation performance of both bio-acids. Additionally, over the designed catalyst, FA is a preferred hydrogen donor than AcOH due to the barrier-free adsorption step while the energy barriers for AcOH decompositions are relatively high.
Orlistatand and Rosuvastatin Suppressed Proliferation of K562 Human Myelogenous Leukemia Cell Line through AMPK/Akt/c-Myc Signaling
Authors: Mojjarad Behnam , Pazhang Yaghub 
Published: March 2020

Abstract
Background: Chronic myeloid leukemia is a myeloproliferative cancer with worldwide incidence, has become as a clinical concern due to chemoresistance in the patients received chemotherapy. Here, we investigated the effect of Orlistat and Rosuvastatin on K562 human myelogenous leukemia cell line in vitro and attempted to illuminate their possible underlying mechanisms. Methods: Cells were exposed to Orlistat and Rosuvastatin, the inhibitors of lipogenesis, then survival and apoptosis rate of K562 cells were examined by MTT assay and flow cytometric analysis respectively. The real time-PCR analysis was used to quantify mRNA levels of Bax, Bcl-2, and Hsp-70 genes. Cell cycle analysis was performed using flow cytometry, whereas the subcellular distribution of c-Myc was measured via immunofluorescence imaging technique. Additionally, the protein level of AMPK, p-AMPK Akt-1, and p-Akt-1 were studied by western blotting.Results: The results showed Orlistat and Rosuvastatin had synergistic anticancer effects on cells and in comparison with the control group, viability and apoptosis rate decreased and increased in treated cells respectively in a dose/time-dependent manner (P<0.05). The mRNA levels of Bax increased while expression of Hsp-70 decreased (P< 0.05). K562 cells treated with Orlistat and Rosuvastatin showed a cell cycle arrest in sub-G1 phase and a decreased level of c-Myc positive cells. Upon outlining the mechanism, it was revealed that AMPK/p-AMPK and p-Akt-1/Akt-1 ratio decreased in treated cells (P< 0.05).Conclusions: Data suggest Orlistat and Rosuvastatin could synergically suppress proliferation of K562 cells through AMPK/Akt/c-Myc axis, proposing a theoretical basis for upcoming application in the treatment of chronic myeloid leukemia.
Total alpha-synuclein assay in the Cerebro-Spinal-Fluid is of interest in the differential diagnosis between Alzheimer's disease and dementia with Lewy bodies from the prodromal stage
Authors: BOUSIGES Olivier , Philippi Nathalie , Lavaux Thomas , Perret-Liaudet Armand , Lachmann Ingolf , Schaeffer-Agalède Caroline , Anthony Pierre , Botzung Anne , Rauch Lucie , Jung Barbara , de Sousa Paulo Loureiro , Demuynck Catherine , Martin-Hunyadi Catherine , Cretin Benjamin , Blanc Frédéric 
Published: March 2020

Abstract
Background: Several studies have investigated the value of alpha-synuclein assay in the cerebrospinal fluid (CSF) of Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB) patients in the differential diagnosis of these two pathologies. However, very few studies have focused on this assay in AD and DLB patients at the MCI stage. Methods: All patients were enrolled under a hospital clinical research protocol from the tertiary Memory Clinic (CM2R) of Alsace by an experienced team of clinicians. A total of 166 patients were included in this study: 21 control subjects (CS), 51 patients with DLB at the prodromal stage (pro-DLB), 16 patients with DLB at the demented stage (DLB-d), 33 AD patients at the prodromal stage (pro-AD) and 32 AD patients at the demented stage (AD-d). CSF levels of total alpha-synuclein were assessed using commercial enzyme-linked immunosorbent assay (ELISA) for alpha-synuclein (AJ Roboscreen). Alzheimer's biomarkers (t-Tau, P-Tau, Aβ42 and Aβ40) were also measured.Results: The alpha-synuclein assays showed a significant difference between the AD and DLB groups. Total alpha-synuclein levels are significantly higher in AD patients than in DLB patients. Interestingly is that the levels seem to be altered from the prodromal stage in both AD and DLB. Furthermore, by dividing the patients according to the profiles of Alzheimer's biomarkers typically found or not for each of the two pathologies and then classifying the patients according to the level of alpha-synuclein, we find that alpha-synuclein levels are elevated not only for AD patients with typical “Alzheimer” profile (i.e. 2 or 3 pathological biomarkers) but also for AD patients with a non-typical “Alzheimer” profile (i.e. none or one pathological biomarker).Conclusions: The modification of total alpha-synuclein levels in the CSF of patients occurs early from the prodromal stage. Moreover, alpha-synuclein assay appears to be of particular interest in the differential diagnosis of AD in cases where the Alzheimer biomarkers do not have a typical profile of the disease, i.e. when there is only one or no pathological biomarker.Trial registration: ClinicalTrials.gov, (AlphaLewyMa, Identifier: NCT01876459)
Influence of MoSi2 on oxidation protective ability of TaB2-SiC coating in oxygen-containing environments within a broad temperature range
Authors: Ren Xuanru , Lv Junshuai , Li Wei , Hu Yuwen , Sun Ke , Ma Can , Chu Hongao , Wang Weiguang , Xu Leihua , Li Ziyu , Feng Peizhong 
Published: March 2020

Abstract
TaB2-SiC coating modified by different content of MoSi2 was fabricated on graphite substrate with SiC inner coating by liquid phase sintering to elevate the anti-oxidation capability of the TaB2-SiC coatings. As compared to the sample with the TaB2-40wt.%SiC coating, the coating sample modified with MoSi2 exhibited a weight gain trend at lower temperatures, the fastest weight loss rate went down by 76%, and the relative oxygen permeability value reduced from about 1% to near 0. More importantly, the large amount of SiO2 glass phase produced over the coating during oxidation was in contact with the modification of MoSi2, which was proved to be beneficial to the dispersion of Ta-oxides. A concomitantly formed continuous Ta-Si-O-B compound glass layer showed excellent capacity to prevent oxygen penetration. However, when the TaB2 content was sacrificed to increase the MoSi2 content, the relative oxygen permeability of the coating increased instead of decreased. Thus, on the basis of ample TaB2 content, increasing the MoSi2 content of the coating is conducive to reducing the relative oxygen permeability of the coatings in a broad temperature region.
Association between autistic traits and home nurture environment: A community-based study
Authors: Qian Sheng , Xu Xin , Wang Ying-Quan , Li Jia-vu , Jia Rui-xia , Li Jing , Xu Yong 
Published: March 2020

Abstract
Background: Increasing attention has been directed toward understanding the ways in which social environmental factors influence children’s behavior, in physical and mental health domains. Autistic traits are continuously distributed in general population and children with autistic traits have great risk of additional mental diseases. However, no literature has demonstrated the relation between autistic traits and home nurture environment.Methods: Caregivers of 408 kindergarten children (68% male) were recruited to complete a series of survey measures in China. The measures used were the Clancy Autistic Behavior Scale and the Home Nurture Environment Scale. Multivariate logistic regression analysis was used to examine the associations.Results: Frequent language/cognition stimulation (aOR 0.520, 95%CI 0.302-0.896), high level of parental warmth (aOR 0.596, 95%CI 0.392-0.905) and high quality of physical living environment (aOR 0.332, 95%CI 0.196-0.561) were the protective factors of autistic traits after controlling the confounding factors. Results were generally not moderated by the child’s gender or birth order.Conclusions: These findings highlight the importance of high levels of home nurture environment for autistic traits and indicate that public health programs should focus on guidance of parents for developing more adequate parenting skills and favorable home nurture environment.
Tectonic plates in 3D mantle convection model with stress- history-dependent rheology
Authors: Miyagoshi Takehiro , Kameyama Masanori , Ogawa Masaki 
Published: March 2020

Abstract
Plate tectonics is a key feature of the dynamics of the Earth’s mantle. By taking into account the stress-history-dependent rheology of mantle materials, we succeeded in realistically producing tectonic plates in our numerical model of mantle convection in a three-dimensional rectangular box. The calculated lithosphere is separated into several pieces (tectonic plates) that rigidly move. Deformation of the lithosphere caused by the relative motion of adjacent plates is concentrated in narrow bands (plate margins) where the viscosity is substantially reduced. The plate margins develop when the stress exceeds a threshold and the lithosphere is ruptured. Once formed, the plate margins persist, even after the stress is reduced below the threshold, allowing the plates to stably move over geologic time. The vertical component of vorticity takes a large value in the narrow plate margins. Secondary convection occurs beneath old tectonic plates as two-dimensional rolls with their axes aligned to the direction of plate motion. The surface heat ﬂow decreases with increasing distance from divergent plate margins (ridges) in their vicinity in the way the cooling half-space model predicts, but it tends towards a constant value away from ridges as observed for the Earth because of the heat transport by the secondary convection.
Role of higher education in the sustainability of water resources: an assessment of institutions in India
Authors: Kansal Arun , Venkatesh G. 
Published: March 2020

Abstract
The motivation behind this paper is to understand the status of water resources management education provided in higher education institutions (HEIs) in India and decipher gaps between what is taught and what is needed in the field. The assessment has been carried out based on the information available on the respective websites of the HEIs using keywords. The authors have also reached out to faculty members and final-year students in universities/HEIs in India. There are a good number of HEIs in India, which offer educational programmes in water-related subjects, though their distribution is skewed and there seems to be a clear bias in favour of the technological aspects of water. Relatively fewer HEIs engage themselves in social, economic and gender-related issues. It is imperative to popularise research in the social, economic and regulatory aspects of water management. Not all HEIs have provided information about the areas of research they engage in, on their websites. Further, a limited number of faculty members and students have responded to the questionnaires. The preparedness of any country in addressing its current challenges can be gauged from the incorporation and subsequent entrenchment of these roles into the fabric of HEIs. This article can be looked upon as reference documents which will go a long way to enabling the identification of synergies, interlinkages and collaboration opportunities to find solutions for a plethora of challenges.
Effects of Broad Spectrum Antibiotics on Measurement of Immunosuppressant Drugs
Authors: Gönel Ataman , Kirhan Idris 
Published: March 2020

Background:
Antibiotics used parenterally can affect blood drug level measurements, as
measured in diagnostic tests.

Objective:
To investigate the effect of six different antibiotics commonly used in intensive care
units on tacrolimus, sirolimus, everolimus and cyclosporin A levels measured by mass spectrometry.

Methods:
Ampicillin + sulbactam (AB1, IV, 1 g), imipenem + cilastatin sodium (AB2, IV, 500
mg), piperacillin + tazobactam (AB3, 4.5 g, IV), ertapenem (AB4, IV, 1 g), meropenem trihydrate
(AB5, 500 mg, IV) and ceftriaxone (AB6, 1 g, IV) antibiotics were used for the interference assay.
Measurements were performed on the Shimadzu 8045 (Japan) LC-MS/MS instrument. Bias values
were calculated.

Results:
The least affected immunosuppressant was cyclosporine A (between -6.88% and 3.40%).
The most affected were everolimus and sirolimus. Ertapenem caused negative interference on the
level of everolimus at the rate of -27.34% and sirolimus at the rate of -26.79%. Piperacillin
+ tazobactam and imipenem + cilastatin sodium caused positive interferences on sirolimus at the
rate of 24.24% and 22.73%, respectively. Ampicillin + sulbactam, meropenem trihydrate and
ceftriaxone affected the sirolimus levels at lower rates (-4.49%, 5.93% and 9.86%). Everolimus
levels deviated at the rate of -11.21% to -16.99% due to imipenem + cilastatin sodium, meropenem
trihydrate and ceftriaxone.

Conclusion:
This study demonstrated the potential of antibiotic use affecting immunosuppressant
levels. Antibiotic interference, especially in transplant patients, may cause erroneous immunosuppression,
increasing the likelihood of rejection.
A Conceptual Study on the Monte Carlo Simulation for Cost Forecasting in the Green Building Project
Authors: Muhamad Halil Faridah , Ismail Hafiszah , Hasim Mohamad Sufian , Hashim Halim 
Published: March 2020

Monte Carlo Simulation is a mathematical technique that generates random variables for modelling risk. This technique is suitable and benefits to the various client such as public and private sector to evaluate the realistic costing proposed by the Quantity Surveyor. Through this approach, quality of life received by the client in investing budget without waste of propose funding in the construction project. The methodology used is a qualitative approach consist of case study and document analysis. The result shows through Monte Carlo simulation, can predict the worst return from the accuracy of the estimation and given absolute confidence for project development.

Keywords: Monte Carlo, Risk Analysis, Cost Prediction, Qualitative Approach

eISSN: 2398-4287 © 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/e-bpj.v5i13.2101