bluuebunny/crossref_metadata_2025_split huggingface dataset:
A tuneable telecom wavelength entangled light emitting diode deployed in an installed fibre network
Authors: Xiang Zi-Heng , Huwer Jan , Skiba-Szymanska Joanna , Stevenson R. Mark , Ellis David J. P. , Farrer Ian , Ward Martin B. , Ritchie David A. , Shields Andrew J. 
Published: July 2020

AbstractEntangled light emitting diodes based on semiconductor quantum dots are promising devices for security sensitive quantum network applications, thanks to their natural lack of multi photon-pair generation. Apart from telecom wavelength emission, network integrability of these sources ideally requires electrical operation for deployment in compact systems in the field. For multiplexing of entangled photons with classical data traffic, emission in the telecom O-band and tuneability to the nearest wavelength channel in compliance with coarse wavelength division multiplexing standards (20 nm channel spacing) is highly desirable. Here we show a fully electrically operated telecom entangled light emitting diode with wavelength tuneability of more than 25 nm, deployed in an installed fibre network. With the source tuned to 1310.00 nm, we demonstrate multiplexing of true single entangled photons with classical data traffic and achieve entanglement fidelities above 94% on an installed fibre in a city.
Does More Compression Mean More Pressure? A New Classification for Muscle Tension Dysphonia
Authors: Fernández Secundino , Garaycochea Octavio , Martinez-Arellano Ana , Alcalde Juan 
Published: July 2020

Objective
The aims of this study were to test the hypothesis that greater supraglottic compression (anteroposterior or lateral) correlates with higher subglottic pressure (SGP) and to develop a classification of muscle tension dysphonia (MTD), based on the degree of supraglottic compression during speech.

Method

A prospective, cross-sectional study was conducted in a series of 37 consecutive patients diagnosed with MTD with an altered aerodynamic profile characterized by high SGP (more than 90 mmH
2
O). Supraglottic anteroposterior and lateral compression were categorized in three grades and assessed during the laryngoscopic examination. All patients completed the Spanish Voice Handicap Index (VHI) questionnaire and completed an acoustic and aerodynamic voice assessment. The relationship between compression grade and VHI with SGP was analyzed.

Results

More than 90% of patients demonstrated some degree of anteroposterior compression, and 67% had some degree of lateral compression. The mean (
SD
) SGP was 111.03 (16.7) mmH
2
O, and the mean VHI was 27.86 (12.5). The degree of SGP was statistically different in the different grades of anteroposterior compression, and also anteroposterior compression correlated with an SGP (
p
< .05). The degree of lateral compression was not correlated with SGP. Neither the degree of anteroposterior or lateral compression nor the value of SGP was found to correlate with VHI.

Conclusions
Because grade of anteroposterior compression correlates with SGP, these grades can be used for diagnosis and follow-up of MTD patients. To this end and on this basis, we propose a new classification for MTD. Unlike the established classification, our proposed one makes it possible to combine different laryngoscopic features, improving the description of the larynx during phonation.
The GAPS programme at TNG
Authors: Barbato D. , Pinamonti M. , Sozzetti A. , Biazzo K. , Benatti S. , Damasso M. , Desidera S. , Lanza A. F. , Maldonado J. , Mancini L. , Scandariato G. , Affer L. , Andreuzzi G. , Bignamini A. , Bonomo A. S. , Borsa F. , Carleo I. , Claudi R. , Cosentino R. , Covino E. , Fiorenzano A. F. M. , Giacobbe P. , Harutyunyan A. , Knapic C. , Leto G. , Lorenzi V. , Maggio A. , Malavolta L. , Micela G. , Molinari E. , Molinaro M. , Nascimbeni V. , Pagano I. , Pedani M. , Piotto G. , Poretti E. , Rainer M. 
Published: July 2020

Context. With the growth of comparative exoplanetology, it is becoming increasingly clear that investigating the relationships between inner and outer planets plays a key role in discriminating between competing formation and evolution models. To do so, it is important to probe the inner region of systems that host long-period giants in search of undetected lower-mass planetary companions.
Aims. In this work, we present our results on the K-dwarf star BD-11 4672, which is already known to host a long-period giant planet, as the first output of a subsample of the GAPS programme specifically aimed at assessing the impact of inefficient migration of planets formed beyond the snowline by searching for Neptune-mass and super-Earth planetary companions of known longer-period giants.
Methods. We used the high-precision HARPS-N observations of BD-11 4672 in conjunction with time series taken from the literature in order to search for additional inner planetary signals to be fitted using differential evolution Markov chain Monte Carlo. The long-term stability of the new orbital solutions was tested with N-body dynamical simulations.
Results. We report the detection of BD-11 4672 c, a new Neptune-mass planet with an orbital period of 74.20−0.08+0.06 d, eccentricity of 0.40−0.15+0.13, semimajor axis of 0.30 ± 0.01 au, and minimum mass 15.37−2.81+2.97 M⊕, orbiting slightly outside the inner edge of the optimistic circumstellar habitable zone. In order to assess its impact on the dynamical stability of the habitable zone, we computed the angular momentum deficit of the system, showing that planet c has a severe negative impact on the stability of possible additional lower-mass temperate planets. The BD-11 4672 system is notable for its architecture, hosting both a long-period giant planet and an inner lower-mass planet, the latter being one of the most eccentric Neptune-mass planets known at similar periods.
Mobile Phone in Stomach—Is Endoscopic Trial Worthwhile?: A Case Report
Authors: Pawar Ankush , Dalal Ashok , Dahale Amol , Sachdeva Sanjeev , Puri Amarender Singh 
Published: July 2020

AbstractA 35-year-old male prisoner with a history of mobile phone ingestion was refereed to our center for management. Clinical examination was unremarkable. After confirmation on abdominal X-ray, we removed it endoscopically without any complication. To the best of our knowledge, this is only the second case report of successful endoscopic removal of mobile phone.
Intrabiliary Acetylcysteine Infusion for Biliary Obstruction in a Case of Chronic Pancreatitis with Pancreatic Head IPMN
Authors: Vincent Paul K. , Ahamed Hasim , Gopalakrishna Rajesh , Menon Ramachandran , Venu Rama P. 
Published: July 2020

AbstractSuccessful biliary drainage in case of intraductal papillary mucinous neoplasm (IPMN) with thick mucus by ERCP and internal drainage alone is usually inadequate. The mucolytic properties of acetylcysteine can offer a therapeutic benefit in this setting. We report a 50-year-old man with chronic pancreatitis and IPMN who had recurrent episodes of biliary obstruction due to mucous occlusion, despite multiple stent exchanges. A nasobiliary catheter was placed and infusion of acetylcysteine was performed which resulted in significant improvement of jaundice. He later underwent surgery after nutritional rehabilitation. This case report highlights the role of intrabiliary acetylcysteine infusions for mucous occlusions in IPMN.
Primary B-Cell Lymphoma of Caecum Presenting as an Ulcerative Lesion in a Young Male
Authors: Bamanikar Arvind , Patil Swapnil , Sharma Shivam 
Published: July 2020

AbstractExtra nodal site of non–Hodgkin’s lymphoma is mostly in the gastrointestinal tract. Large intestine is rarely affected compared with stomach or small bowel. The colon is affected in 0.4% of cases approximately. High index of suspicion is required to establish the diagnosis, since there may be no specific signs. Here we report a case of a 28-year-old male, who presented with diarrhea , abdominal pain and weight loss of 2-month duration and diagnosed as non-Hodgkin’s lymphoma (NHL) of the cecum as B-cell lymphoma, unclassified (BCLU) according to World Health Organization (WHO) guidelines.
Exchange of Clinical and Omics Data According to FAIR Principles: A Review of Open Source Solutions
Authors: Pugliese Philipp , Knell Christian , Christoph Jan 
Published: July 2020

Abstract
Background Due to the ongoing increase and importance of the sustainable reusability of data, the findable, accessible, interoperable, reusable or FAIR principles were developed which are also relevant in translational research.
Objectives The study aims at identification of platforms by literature search that are suitable for implementation in translational research, in particular with regard to their FAIRness.
Methods The collected information is summarized and compared.
Results Platforms have been identified which are suitable for linking with other translational platforms with regard to documentation, long-term archiving, and processing as well as for FAIR handling of bioinformatic data.
Conclusion There are already platforms in the translational environment that take FAIR principles into account and thus improve translational research. Due to the specialization of the research platforms and the fact that FAIR are only principles and not standards, the platforms have to be examined in individual cases to see whether and how they can be integrated with other platforms.
Mantle Cell Lymphoma Presenting as Multiple Lymphomatous Polyposis of the Colon
Authors: Shafiq Syed , Ramesh Ganesh Narayan , Khandagale Varun 
Published: July 2020

AbstractMantle cell lymphoma (MCL) is a subset of B-cell non-Hodgkin’s lymphoma with a tendency to involve the gastrointestinal (GI) tract and presents as multiple lymphomatous polyposis of one or multiple segments of the GI tract. Here, we report an unusual case of a 58-year-old female presenting with chief complaints of constipation, bleed per rectum, and unintentional weight loss of 15 kg over 6 months. Colonoscopy revealed the entire colon to be studded with polypoidal lesions of varying sizes which were biopsied. Histopathological examination and immunohistochemistry confirmed the polypoidal lesions to represent MCL. Computed tomography scan showed numerous variable-sized polypoidal lesions scattered throughout the entire colon along with paraaortic and mesenteric lymphadenopathy. Thus far, she has undergone three cycles of chemotherapy with R-CHOP resulting in significant tumor reduction and symptomatic improvement in her well-being.
Push Enteroscopy Guided Removal of a Sharp Foreign Body from the Midjejunum in a Child
Authors: Sundaram Sridhar , Giri Suprabhat , Patra Biswaranjan , Darak Harish , Bhatia Shobna 
Published: July 2020

Abstract
Background The majority of foreign bodies entering the small intestine are passed spontaneously. However, in case of a sharp object, its removal is an urgency due to a higher risk of intestinal perforation, and endoscopic intervention is an appropriate management strategy as surgery is associated with greater morbidity. Although enteroscopy is the standard practice for the removal of a foreign body in the small intestine, gastroduodenoscopy may be used for small intestinal foreign body removal.
Case Presentation We describe here the case of a 21-month-old child in whom a 5-cm, sharp-pointed nail in the midjejunum was removed successfully by a gastroduodenoscopy. This case highlights the difficulties in the removal of a sharp foreign body in a pediatric patient and the use of push enteroscopy.
Conclusion Gastroduodenoscopy can be used for the removal of a foreign body in the small intestine in pediatric population in a resource-limited setup by performing push enteroscopy.
From Raw Data to FAIR Data: The FAIRification Workflow for Health Research
Authors: Sinaci A. Anil , Núñez-Benjumea Francisco J. , Gencturk Mert , Jauer Malte-Levin , Deserno Thomas , Chronaki Catherine , Cangioli Giorgio , Cavero-Barca Carlos , Rodríguez-Pérez Juan M. , Pérez-Pérez Manuel M. , Laleci Erturkmen Gokce B. , Hernández-Pérez Tony , Méndez-Rodríguez Eva , Parra-Calderón Carlos L. 
Published: July 2020

Abstract
Background FAIR (findability, accessibility, interoperability, and reusability) guiding principles seek the reuse of data and other digital research input, output, and objects (algorithms, tools, and workflows that led to that data) making them findable, accessible, interoperable, and reusable. GO FAIR - a bottom-up, stakeholder driven and self-governed initiative - defined a seven-step FAIRification process focusing on data, but also indicating the required work for metadata. This FAIRification process aims at addressing the translation of raw datasets into FAIR datasets in a general way, without considering specific requirements and challenges that may arise when dealing with some particular types of data.
Objectives This scientific contribution addresses the architecture design of an open technological solution built upon the FAIRification process proposed by “GO FAIR” which addresses the identified gaps that such process has when dealing with health datasets.
Methods A common FAIRification workflow was developed by applying restrictions on existing steps and introducing new steps for specific requirements of health data. These requirements have been elicited after analyzing the FAIRification workflow from different perspectives: technical barriers, ethical implications, and legal framework. This analysis identified gaps when applying the FAIRification process proposed by GO FAIR to health research data management in terms of data curation, validation, deidentification, versioning, and indexing.
Results A technological architecture based on the use of Health Level Seven International (HL7) FHIR (fast health care interoperability resources) resources is proposed to support the revised FAIRification workflow.
Discussion Research funding agencies all over the world increasingly demand the application of the FAIR guiding principles to health research output. Existing tools do not fully address the identified needs for health data management. Therefore, researchers may benefit in the coming years from a common framework that supports the proposed FAIRification workflow applied to health datasets.
Conclusion Routine health care datasets or data resulting from health research can be FAIRified, shared and reused within the health research community following the proposed FAIRification workflow and implementing technical architecture.
Outcomes of Double Balloon Enteroscopy for Managing Overt Small Bowel Bleeding
Authors: Dalal Ankit , Patil Gaurav , Maydeo Amit 
Published: July 2020

Abstract
Background The commonest therapeutic indications for double balloon enteroscopy (DBE) includes removal of retained video capsules, dilatation of strictures, polypectomy, and managing obscure small bowel bleeding. We review our experience in managing active small bowel bleeding with DBE.
Methods A retrospective review was done for all the cases undergoing DBE from August 2017 to July 2019. Patient follow-up data was collected.
Results Among 25 cases with a median age of 46.8 (range 25–65 years), 17 males (68%) underwent DBE for suspected small bowel bleeding. The commonest presenting complaint was melena 19 (76%). The findings were positive (diagnostic yield) in 18 (72%) patients with an antegrade approach. Active bleeding was associated with Dieulafoy's lesion (n = 6), gastrointestinal stromal tumors (GIST) (n = 4), jejunal varices (n = 3), angioectasia (n = 3), and ulcer (n = 2), who then underwent successful intervention. The rest of the patients underwent both antegrade and retrograde approach but failed to immediately identify an alternative diagnosis. Mean (standard deviation [SD]) time taken for antegrade enteroscopy was 96.7 (15.3) mins and 67.8 (13.6) mins for retrograde enteroscopy. The median duration between the last bleeding episode and timing of DBE was 9 (range 6–15 hours). No major complications were seen during or immediately postprocedure.
Conclusion DBE is useful in identifying and treating active small bowel bleeding. Being invasive and time-intensive, it is easy to miss lesions and, therefore, needs appropriate expertise. DBE does appear to be relatively cheaper, with better patient acceptance and time saving.
Clinical and Magnifying Narrow-Band Imaging Endoscopic Finding–Olmesartan-Associated Collagenous Gastroduodenitis
Authors: Desai Pankaj , Patel Chintan , Kabrawala Mayank , Nandwani Subhash , Arora Priya , Parekh Krishna 
Published: July 2020

AbstractCollagenous gastroduodenitis is a rare and may be associated with olmesartan, an angiotensin–II receptor antagonist used for management of hypertension. It is characterized by marked subepithelial collagen deposition with mucosal inflammatory infiltrate. The characteristic endoscopic finding of collagenous gastritis is nodular mucosa and other findings include erythema friability, erosions, ulcers and atrophy. Olmesartan-associated collagenous gastroduodenitis without colonic involvement is exceptionally rare with only one case reported in literature to date. The association may be difficult to recognize because of its clinical and histologic similarity to the clinical entity collagenous gastroduodenitis. We present a case of Olmesartan-associated collagenous gastroduodenitis, which was observed on magnifying narrow-band imaging endoscopic findings.
Optically pumped semiconductor laser based on a type-II CdS/ZnSe heterostructure
Authors: Butaev M.R. , Kozlovsky V.I. , Skasyrsky Ya.K. 
Published: July 2020

AbstractAn optically pumped semiconductor laser based on a type-II CdS/ZnSe nanoheterostructure containing 10 quantum wells (QWs) was studied. The structure was grown by metal-organic vapour phase epitaxy on a GaAs substrate. The lifetime of electron-hole pairs at a low pump level was measured by luminescence decay to be ∼0 ns. The peak power of the microcavity semiconductor laser at room temperature and longitudinal pumping by a repetitively pulsed N2laser was 7.2 W at a wavelength of 514 nm. The relatively low laser slope efficiency (0.35 %) is explained by amplified spontaneous emission propagating along the structure. The peak power and efficiency of the laser in the case of transverse pumping increase to 70 W and 3.5 %, respectively.
Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation
Authors: Chan Denice T. Y. , Jenkinson Lesley , Haynes Stuart W. , Austin Mark , Diamandakis Agata , Burschowsky Daniel , Seewooruthun Chitra , Addyman Alexandra , Fiedler Sebastian , Ryman Stephanie , Whitehouse Jessica , Slater Louise H. , Gowans Ellen , Shibata Yoko , Barnard Michelle , Wilkinson Robert W. , Vaughan Tristan J. , Holt Sarah V. , Cerundolo Vincenzo , Carr Mark D. , Groves Maria A. T. 
Published: July 2020

Significance
We describe an antibody optimization strategy that seeks to overcome the restrictive nature of existing affinity-maturation methods, by rapidly exploring a vast sequence space in an unbiased manner through application of PCR techniques and ribosome display. We exemplified the significance of this method by contrasting the crystal structure of the parent and optimized antibodies bound to Arginase 2, which revealed a striking reorientation of the binding paratope, concurrent with distinct improvements in inhibitory potency and binding properties. The nature and magnitude of the epitope expansion was extraordinary and unlikely to have been produced through conventional affinity-maturation methods. This innovative approach demonstrates broad applicability to the optimization of candidate therapeutic antibodies, even those less amenable to CDRH3 targeting.
New interpretation and techniques of transcreation
Authors: Du Chen 
Published: July 2020

Abstract
This article points out some “loopholes” in the traditional Chinese-English translation theories, and proposes
several transcreation theories to countermeasure the “loopholes”, illustrating non-equivalences. In particular, the article
proposes a novel translation/transcreation theory that incorporates the writing field, in both the source and target languages,
into the traditional translation field. This is for the purpose of cultural transmission and integration. In addition, the article
illustrates the relationship between translation and writing by dissecting the translation/transcreation process into two
processes: understanding and writing. Moreover, it suggests that the transcreation field develop some criteria, such as: fidelity,
flexibility and creativity, and that all the science, social science and humanities subareas in the transcreation field are
categorized according to these criteria. In order to support the transcreation theories and multidisciplinary translation theories
proposed in this article, some typical examples and transcreation techniques that push the envelope of existing transcreation
theories are provided. This article may shed new light on the limitations of, and possible solutions to, machine translation. It
may also answer questions like: “Is understanding unimportant to machine translation?”
The commitment to sustainable tourism and the development of indigenous tourism in Chile.
Authors: de la Maza Francisca , Calfucura Enrique 
Published: July 2020

Abstract

This chapter offers a critical analysis of tourism development policy in Chile. It specifically analyses the commitment of public policy to sustainability as a pillar of indigenous tourism and highlights the contradictions of tourism development under the country's economic model. It is acknowledged that there are contradictions between promotion of the indigenous world as part of what the country offers in terms of sustainable tourism and the difficulties in the political recognition of its indigenous peoples. The chapter documents that in various parts of the country tourism has developed massively and with little regulation, and that indigenous territories have become natural and cultural attractions with little control over their territories and implementation of their specific rights. It is concluded that it is difficult to put into practice a type of tourism that is governed by the principles of sustainability as well as the recognition of the needs and desires of the indigenous population.
Development and validation of an economical uric acid-Fe3+/Fe2+-ferrozine-based colorimetric assay to estimate uric acid level of pure and biological samples
Authors: Akram Maryam , Asghar Muhammad Nadeem , Saleem Khan Maria , Shahid Sammia , Abdur Rahman Hafiz Muhammad , Nadeem Iram 
Published: July 2020

Abstract
This work presents the development and validation of a simple, rapid, and cost-effective spectrophotometric method for quantitative analysis of uric acid in biological samples. The method relies upon uric acid-led reduction of Fe(III) to Fe(II) of sample/standard solutions which stoichiometrically engages ferrozine to form a magenta-colored complex. Different parameters including pH, metal and chelator concentrations, temperature, etc., were optimized for the maximum intensity and stability of the complex. The uric acid concentrations of synthetic/plasma solutions were determined by comparing the color intensity of Fe(ferrozine)32+ complex produced by test solution with the standard curve formed by known uric acid concentrations. The method was validated in accordance with ICH guidelines and subjected to human plasma analysis. The results obtained were compared with a reference (enzymatic) method which revealed that there was no significant difference between the two methods at 95% confidence level. The method is highly specific, precise, linear, accurate, and robust.