bluuebunny/crossref_metadata_2025_split huggingface dataset:
Critical Mindfulness in Social Work: Exploring the Potential of Reflexive Self-Care in the Journey from Student to Social Worker
Authors: McCusker Pearse 
Published: December 2020

AbstractThis article reports on one aspect of a study investigating mindfulness in social work education and practice. Specifically, it explores its potential as a reflexive form of self-care in the journey from student to newly qualified social worker. Comprising a participatory action research approach, longitudinal qualitative design and bespoke mindfulness programme that included compassion-based and non-violent communication practices, the study tracked six participants who completed the programme from the end of the first year of their MSc in Social Work to six months into post-qualifying practice. The experiences of three other participants who were unable to complete were also considered. Data were gathered using interviews, discussions groups, questionnaires and the researchers’ reflections and analysed using thematic and framework analysis, and transformative learning theory. The findings suggest that a critical framing of mindfulness encouraged reflexive forms of self-care in three key ways: validating the importance of self-care and developing awareness of internalised oppression; supporting reflexive engagement with service users; and better mitigating work-related stress and role conflict. Further study of these emergent findings is recommended, focusing on the synergies between critical mindfulness and reflexivity and the profession’s social justice aims.
Multivariate morphometric analysis supported by an anatomical approach to assess species delimitation inXyris(Xyridaceae) in New Caledonia
Authors: Morel Jérémie , Le Moguédec Gilles , Munzinger Jérôme 
Published: December 2020

AbstractXyridaceae are represented in New Caledonia only by the genus Xyris, the description of which was last revised in the 1960s, and three endemic species were recognized there at that time, X. pancheri, X. neocaledonica and X. guillauminii. However, no specimens of X. guillauminii were reported from P or L, although some type material was present. In addition, most material was unidentified at the species level in international herbaria (up to 45% for the NOU herbarium), showing that the family had not been studied in the framework of the Flore de la Nouvelle-Calédonie. In total, 129 herbarium specimens were examined for an ascendant hierarchical classification and a principal coordinates analysis based on 18 morphological characters regarded as diagnostic at the species level (including six used in the original revision). The analyses revealed three well-delimited groups that potentially correspond to species-level units. A sub-sampling of 21 specimens, representative of these three groups, was studied anatomically (leaf cross-sections) and by scanning electron microscopy (leaf surface and seeds) and provided ten additional characters. This additional dataset validated the taxonomy in three species-level units. The resulting entities were then compared with nomenclatural types, which showed that the first corresponded to X. neocaledonica, the second represents a well-delimited, undescribed species, and the third includes types of both X. pancheri and X. guillauminii, this last being in need of synonymization. The findings of the present study provide a basis for undertaking a taxonomic revision of Xyris in New Caledonia, including the description of the new species. All New Caledonian species have an axile placentation and a trilocular ovary, so they belong to Xyris section Pomatoxyris, which is no longer endemic to Australia.
Global Network Organization of the Fetal Functional Connectome
Authors: De Asis-Cruz Josepheen , Andersen Nicole , Kapse Kushal , Khrisnamurthy Dhineshvikram , Quistorff Jessica , Lopez Catherine , Vezina Gilbert , Limperopoulos Catherine 
Published: December 2020

AbstractRecent advances in brain imaging have enabled non-invasive in vivo assessment of the fetal brain. Characterizing brain development in healthy fetuses provides baseline measures for identifying deviations in brain function in high-risk clinical groups. We examined 110 resting state MRI data sets from fetuses at 19 to 40 weeks’ gestation. Using graph-theoretic techniques, we characterized global organizational features of the fetal functional connectome and their prenatal trajectories. Topological features related to network integration (i.e., global efficiency) and segregation (i.e., clustering) were assessed. Fetal networks exhibited small-world topology, showing high clustering and short average path length relative to reference networks. Likewise, fetal networks’ quantitative small world indices met criteria for small-worldness (σ &gt; 1, ω = [−0.5 0.5]). Along with this, fetal networks demonstrated global and local efficiency, economy, and modularity. A right-tailed degree distribution, suggesting the presence of central areas that are more highly connected to other regions, was also observed. Metrics, however, were not static during gestation; measures associated with segregation—local efficiency and modularity—decreased with advancing gestational age. Altogether, these suggest that the neural circuitry underpinning the brain’s ability to segregate and integrate information exists as early as the late 2nd trimester of pregnancy and reorganizes during the prenatal period.Significance statement.Mounting evidence for the fetal origins of some neurodevelopmental disorders underscores the importance of identifying features of healthy fetal brain functional development. Alterations in prenatal brain connectomics may serve as early markers for identifying fetal-onset neurodevelopmental disorders, which in turn provide improved surveillance of at-risk fetuses and support the initiation of early interventions.
A comparative analysis of premature heart disease- and cancer-related mortality in women in the USA, 1999–2018
Authors: Khan Safi U , Yedlapati Siva H , Lone Ahmad N , Khan Muhammad Shahzeb , Wenger Nanette K , Watson Karol E , Gulati Martha , Hays Allison G , Michos Erin D 
Published: December 2020

Abstract

Aims
To compare premature heart disease- and cancer-related deaths in women in the USA.

Methods and results
We analysed the US national database of death certificates of women aged &lt;65 from the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research database between 1999 and 2018. We measured annual percentage changes (APCs) in age-adjusted mortality rates (AAMRs) and years of potential life lost per 100 000 persons due to heart disease and cancer. Overall, cancer was a more prevalent cause of premature death compared with heart disease. Between 1999 and 2018, the AAMRs decreased for both cancer (61.9/100 000 to 45.6/100 000) and heart disease (29.2/100 000 to 22.6/100 000). However, while APC in AAMR for cancer declined consistently over time, after an initial decline, APC in AAMR for heart disease increased between 2010 and 2018 [0.53 95% confidence interval (0.18–0.89)], with a significant rise in Midwest, medium/small metros, and rural areas after 2008. Compared with cancer, APC in AAMR for heart disease increased in women aged 25–34 years [2.24 (0.30–4.22); 2013–18) and 55–64 years [0.46 (0.13–0.80); 2009–13], as well as Non-Hispanic (NH) Whites [APC, 0.79 (0.46–1.13); 2009–18] and NH American Indian/Alaskan Native [2.71 (0.59–4.87); 2011–2018]. Consequently, the mortality gap between cancer and heart disease has narrowed from an AAMR of 32.7/100 000 to 23.0/100 000.

Conclusions
The mortality gap between cancer and heart disease is decreasing among women &lt;65 years. Intensive cardiovascular health interventions are required focusing on vulnerable young demographic subgroups and underserved regional areas to meet the American Heart Association’s Impact Goal and Million Hearts Initiative.
d-Tartrate utilization correlates with phylogenetic subclade inPseudomonas cichorii
Authors: Iiyama Kazuhiro , Tani Sayo , Yagi Haruka , Hashimoto Sara , Suga Yasuhiro , Tsuchiya Kenichi , Furuya Naruto 
Published: December 2020

ABSTRACTPseudomonas cichorii is divided into two subclades based on the 16S ribosomal RNA gene sequence and core genome multilocus sequence typing. It was shown that subclade 2 strains utilize d-tartrate as a sole carbon source, whereas subclade 1 strains do not. Draft genome sequencing was performed with P. cichorii strains to identify d-tartrate utilization genes. By genome comparative and homology search studies, an ∼7.1-kb region was identified to be involved in d-tartrate utilization. The region is subclade 2 specific, and contains tarD and dctA genes, which encode a putative enzyme and transporter of d-tartrate, respectively. When the region was introduced into subclade 1 strains, the transformants were able to utilize d-tartrate. Partial fragments of tarD and dctA were amplified from all subclade 2 strains tested in this study by PCR using gene-specific primers, but not from subclade 1 strains. This is the first report on the genetic analysis of biochemical characteristics corresponding to a specific phylogenetic group in P. cichorii.
Multitemporal hyperspectral tree species classification in the Białowieża Forest World Heritage site
Authors: Modzelewska Aneta , Kamińska Agnieszka , Fassnacht Fabian Ewald , Stereńczak Krzysztof 
Published: December 2020

Abstract
Tree species composition maps derived from hyperspectral data have been found to be accurate but it is still unclear whether an optimal time window exists to acquire the images. Trees in temperate forests are subject to phenological changes that are species-specific and can have an impact on species recognition. Our study examined the performance of a multitemporal hyperspectral dataset to classify tree species in the Polish part of the Białowieża Forest. We classified seven tree species including spruce (Picea abies (L.) H.Karst), pine (Pinus sylvestris L.), alder (Alnus glutinosa Gaertn.), oak (Quercus robur L.), birch (Betula pendula Roth), hornbeam (Carpinus betulus L.) and linden (Tilia cordata Mill.), using Support Vector Machines. We compared the results for three data acquisitions—early and late summer (2–4 July and 24–27 August), and autumn (1–2 October) as well as a classification based on an image stack containing all three acquisitions. Furthermore, the sizes (height and crown diameter) of misclassified and correctly classified trees of the same species were compared. The early summer acquisition reached the highest accuracies with an Overall Accuracy (OA) of 83–94 per cent and Kappa (κ) of 0.80–0.92. The classification based on the stacked multitemporal dataset resulted in slightly higher accuracies (84–94 per cent OA and 0.81–0.92 κ). For some species, e.g. birch and oak, tree size differed notably for correctly and incorrectly classified trees. We conclude that implementing multitemporal hyperspectral data can improve the classification result as compared with a single acquisition. However, the obtained accuracy of the multitemporal image stack was in our case comparable to the best single-date classification and investing more time in identifying regionally optimal acquisition windows may be worthwhile as long hyperspectral acquisitions are still sparse.
Predictors of lymph-node metastasis in surgically resected T1 colorectal cancer in Western populations
Authors: Zong Zhen , Li Hui , Hu Ce-Gui , Tang Fu-Xin , Liu Zhi-Yang , Deng Peng , Zhou Tai-Cheng , Yi Cheng-Hao 
Published: December 2020

Abstract

Background
The risk of lymph-node metastasis (LNM) in T1 colorectal cancer (CRC) has not been well documented in heterogeneous Western populations. This study investigated the predictors of LNM and the long-term outcomes of patients by analysing T1 CRC surgical specimens and patients’ demographic data.

Methods
Patients with surgically resected T1 CRC between 2004 and 2014 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Patients with multiple primary cancers, with neoadjuvant therapy, or without a confirmed histopathological diagnosis were excluded. Multivariate logistic-regression analysis was used to identify the predictors of LNM.

Results
Of the 22,319 patients, 10.6% had a positive lymph-node status based on the final pathology (nodal category: N1 9.6%, N2 1.0%). Younger age, female sex, Asian or African-American ethnicity, poor differentiation, and tumor site outside the rectum were significantly associated with LNM. Subgroup analyses for patients stratified by tumor site suggested that the rate of positive lymph-node status was the lowest in the rectum (hazard ratio: 0.74; 95% confidence interval: 0.63–0.86).

Conclusion
The risk of LNM was potentially lower in Caucasian patients than in API or African-American patients with surgically resected T1 CRC. Regarding the T1 CRC site, the rectum was associated with a lower risk of LNM.
Polygenic Risk Score of Longevity Predicts Longer Survival Across an Age Continuum
Authors: Tesi Niccolo’ , van der Lee Sven J , Hulsman Marc , Jansen Iris E , Stringa Najada , van Schoor Natasja M , Scheltens Philip , van der Flier Wiesje M , Huisman Martijn , Reinders Marcel J T , Holstege Henne 
Published: December 2020

Abstract
Studying the genome of centenarians may give insights into the molecular mechanisms underlying extreme human longevity and the escape of age-related diseases. Here, we set out to construct polygenic risk scores (PRSs) for longevity and to investigate the functions of longevity-associated variants. Using a cohort of centenarians with maintained cognitive health (N = 343), a population-matched cohort of older adults from 5 cohorts (N = 2905), and summary statistics data from genome-wide association studies on parental longevity, we constructed a PRS including 330 variants that significantly discriminated between centenarians and older adults. This PRS was also associated with longer survival in an independent sample of younger individuals (p = .02), leading up to a 4-year difference in survival based on common genetic factors only. We show that this PRS was, in part, able to compensate for the deleterious effect of the APOE-ε4 allele. Using an integrative framework, we annotated the 330 variants included in this PRS by the genes they associate with. We find that they are enriched with genes associated with cellular differentiation, developmental processes, and cellular response to stress. Together, our results indicate that an extended human life span is, in part, the result of a constellation of variants each exerting small advantageous effects on aging-related biological mechanisms that maintain overall health and decrease the risk of age-related diseases.
Obtaining Information From Different Sources Matters During the COVID-19 Pandemic
Authors: Chu Li , Fung Helene H , Tse Dwight C K , Tsang Vivian H L , Zhang Hanyu , Mai Chunyan 
Published: December 2020

AbstractBackground and ObjectivesOlder adults might be less information-seeking in comparison to younger adults. Yet, when a crisis hits, rather than relying on only a few information sources, it is important for people to gather information from a variety of different sources. With more information sources, people are more likely to obtain a more realistic perception of the situation and engagement of health behaviors. This study examined the association between age and information-seeking patterns, and how information-seeking patterns influenced worry about coronavirus disease 2019 (COVID-19) and protective measures taken during the pandemic.Research Design and MethodsThis study was conducted from March to May 2020. Ninety younger adults and 105 older adults were recruited in a 21-day daily diary study. Participants reported the types of sources where they received COVID-19-related information, worry from these information sources and protective health behaviors performed each day. Multilevel serial mediation analysis was performed.ResultsConcurrent and time-lagged analyses both revealed that older adults received information from more sources, and more frequently from traditional (e.g., newspaper and TV) and interpersonal sources (e.g., information shared by friends and families), than did younger adults. When receiving information from more sources, older adults were more worried about COVID-19 and performed more protective health behaviors.Discussion and ImplicationsThese results demonstrated the utility of having more information sources in the context of a public health crisis and offered suggestions for future public communication and community engagement.
Permanently Online—Always Stressed Out? The Effects of Permanent Connectedness on Stress Experiences
Authors: Freytag Anna , Knop-Huelss Katharina , Meier Adrian , Reinecke Leonard , Hefner Dorothée , Klimmt Christoph , Vorderer Peter 
Published: December 2020

Abstract
Concerns have been expressed that permanent online connectedness might negatively affect media user’s stress levels. Most research has focused on negative effects of specific media usage patterns, such as media multitasking or communication load. In contrast, users’ cognitive orientation toward online content and communication has rarely been investigated. Against this backdrop, we examined whether this cognitive orientation (i.e., online vigilance with its three dimensions salience, reactibility, monitoring) is related to perceived stress at different timescales (person, day, and situation level), while accounting for the effects of multitasking and communication load. Results across three studies showed that, in addition to multitasking (but not communication load), especially the cognitive salience of online communication is positively related to stress. Our findings are discussed regarding mental health implications and the origins of stress.
Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice
Authors: Pattamatta Amrutha , Nguyen Lien , Olafson Hailey R , Scotti Marina M , Laboissonniere Lauren A , Richardson Jared , Berglund J Andrew , Zu Tao , Wang Eric T , Ranum Laura P W 
Published: December 2020

Abstract
C9orf72 ALS/FTD patients show remarkable clinical heterogeneity, but the complex biology of the repeat expansion mutation has limited our understanding of the disease. BAC transgenic mice were used to better understand the molecular mechanisms and repeat length effects of C9orf72 ALS/FTD. Genetic analyses of these mice demonstrate that the BAC transgene and not integration site effects cause ALS/FTD phenotypes. Transcriptomic changes in cell proliferation, inflammation and neuronal pathways are found late in disease and alternative splicing changes provide early molecular markers that worsen with disease progression. Isogenic sublines of mice with 800, 500 or 50 G4C2 repeats generated from the single-copy C9–500 line show longer repeats result in earlier onset, increased disease penetrance and increased levels of RNA foci and dipeptide RAN protein aggregates. These data demonstrate G4C2 repeat length is an important driver of disease and identify alternative splicing changes as early biomarkers of C9orf72 ALS/FTD.
What Factors Drive Transport and Logistics Costs in Africa?
Authors: Plane Patrick 
Published: December 2020

Abstract
We analyze the domestic transport and logistics costs of importing a 20-foot container into Africa. We run regressions on a panel of 50 African countries for the period 2006–2014 using the RE-2SLS estimator. Distance from port of arrival to the point of delivery is an important explanatory factor of cost. Time-varying variables yield additional and valuable information. Reducing processing times and adjusting the ratio of the purchasing power parity conversion factor to the market exchange rate would contribute to save on the cost to import.
The impact of time spent on the electronic health record after work and of clerical work on burnout among clinical faculty
Authors: Peccoralo Lauren A , Kaplan Carly A , Pietrzak Robert H , Charney Dennis S , Ripp Jonathan A 
Published: December 2020

Abstract

Objective
To identify specific thresholds of daily electronic health record (EHR) time after work and daily clerical time burden associated with burnout in clinical faculty.

Materials and Methods
We administered an institution-wide survey to faculty in all departments at Mount Sinai Health System from November 2018 to February 2019. The Maslach Burnout Inventory and Mayo Well-Being Index assessed burnout. Demographics, possible confounding variables, and time spent on EHR work/clerical burden were assessed.

Results
Of 4156 eligible faculty members, 1781(42.9%) participated in the survey. After adjustment for background factors, EHR frustration (odds ratio [OR]=1.64–1.66), spending &gt;90 minutes on EHR-outside the workday by self-report (OR = 1.41–1.90) and &gt;1 hour of self-reported clerical work/day (OR = 1.39) were associated with burnout. Reporting that one’s practice unloads clerical burden (OR = 0.50–0.66) and higher resilience scores (OR = 0.77–0.84) were negatively associated with burnout.
Spending &gt;90 minutes/day on EHR-outside work (OR = 0.66–0.67) and &gt;60 minutes/day on clerical work (OR = 0.54–0.58) was associated with decreased likelihood of satisfactory work–life integration (WLI) and professional satisfaction (PS). Greater meaning in work was associated with an increased

likelihood
of achieving WLI (OR = 2.51) and PS (OR = 21.67).

Conclusion
Results suggest there are thresholds of excessive time on the EHR-outside the workday (&gt;90 minutes) and overall clerical tasks (&gt;60 minutes), above which clinical faculty may be at increased risk for burnout, as well as reduced WLI and PS, independent of demographic characteristics and clinical work hours. These thresholds of EHR and clerical burden may inform interventions aimed at mitigating this burden to reduce physician burnout.
Evaluating human–coyote encounters in an urban landscape using citizen science
Authors: Drake David , Dubay Shelli , Allen Maximilian L 
Published: December 2020

AbstractCoyotes are ubiquitous in habitats across North America, including in urban areas. Reviews of human–coyote encounters are limited in scope and analysis and predominantly document encounters that tend to be negative, such as human–wildlife conflict, rather than benign experiences. The objective of our study was to use citizen science reports of human–coyote interactions entered into iNaturalist to better understand the range of first person accounts of human–coyote encounters in Madison, WI. We report 398 citizen science accounts of human–coyote encounters in the Madison area between October 2015 and March 2018. Most human–coyote encounters occurred during coyote breeding season and half of all encounters occurred in moderate development land cover. Estimated level of coyote aggressiveness varied significantly, with 90% of citizen scientists scoring estimated coyote aggression as a 0 and 7% scoring estimated aggression as a 1 on a 0–5 scale (with 0 being calm and 5 being aggressive). Our best performing model explaining the estimated distance between the human observer and a coyote (our proxy for a human–coyote encounter) included the variables distance to nearest paved road, biological season of the year relative to coyote life history, and time of day/night. We demonstrate that human–coyote interactions are regularly more benign than negative, with almost all first-hand reported human–coyote encounters being benign. We encourage public outreach focusing on practices that can foster benign encounters when educating the public to facilitate human–coyote coexistence.