bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consumer preferences for beef with improved nutrient profile1
Authors: Flowers Sarah , McFadden Brandon R , Carr Chad C , Mateescu Raluca G 
Published: October 2019

Abstract
Although beef is a nutrient-rich foodstuff excelling in protein, vitamins, and minerals, there is controversy regarding the fat content of beef and its healthfulness in the diet. Although much of the fatty acid (FA) content in beef is considered “healthy fats,” many consumers are confused about the different classifications of FA. The objectives of this study were to determine consumers’ knowledge about the nutritional value of beef and its importance in purchasing decisions, and to gain a better understanding about preferences for changes in FA composition. Objectives of the study were completed through 2 consumer studies: 1) an online survey and 2) a taste-panel auction. In the online survey, respondents were asked to choose between 2 steaks that varied in polyunsaturated and saturated FA levels, iron content, and price. Respondents were also asked to categorize “Monounsaturated Fat,” “Polyunsaturated Fat,” “Saturated Fat,” and “Trans Fat,” as either “healthy” or “unhealthy” both before and after an educational excerpt was provided. The results from the online survey indicated many consumers are unclear about the differences in beef nutritional value, specifically FA content. Initially, only 66.4%, 69.1%, 79.1%, and 79.2% of respondents correctly categorized the monounsaturated, polyunsaturated, saturated, and trans fat, respectively. However, more than 90% of respondents correctly categorized the various FAs after an educational excerpt was provided. After survey respondents better understood the healthfulness of FA in beef, they were also willing to pay a premium for a steak with improved FA composition. However, these premiums diminished when participants had to actually put forth a monetary value for a steak in the taste-panel auction. Research shows that there is variation among cattle for FA composition. This provides opportunity to identify cattle with a favorable composition and market this product to the increasing population of health-conscious consumers. Our results provide insight for beef promotion and marketing opportunities and indicate that relaying information about FA content is extremely important to collect a premium for healthier beef.
Using the difference in actual and expected calf liveweight relative to its dam liveweight as a statistic for interherd and intraherd benchmarking and genetic evaluations1
Authors: McHugh Noirin , Evans Ross D , Berry Donagh P 
Published: October 2019

Abstract
The importance of improving the efficiency of beef production systems using both genetic and management strategies has long been discussed. Despite the contribution of the mature beef herd to the overall cost of production in the sector as a whole, most strategies for improving (feed) efficiency have focused on the growing animal. The objective of the present study was to quantify the phenotypic and genetic variability in several novel measures that relate the weight of a calf to that of its dam and vice versa. Two novel residual traits, representing the deviation in calf weight relative to its expectation from the population based on its dam’s weight (DIFFcalf) or the deviation in the weight of the dam relative to its expectation from the population based on its calf’s weight (DIFFdam), were calculated while simultaneously accounting for some nuisance factors in a multiple regression model. Four supplementary traits were also calculated, namely, 1) the deviation in calf weight from its expectation expressed relative to the weight of the dam (DIFFcalf_ratio), 2) the deviation in dam weight from its expectation relative to the weight of the dam (DIFFdam_ratio), 3) DIFFcalf-DIFFdam, and 4) the simple ratio of calf weight to its dam’s weight (RATIOcalfdam). Genetic and residual variance components for each of the 6 traits were estimated using animal–dam linear mixed models. The phenotypic SD for DIFFcalf was 42 kg and, when expressed relative to the weight of the dam (i.e., DIFFcalf_ratio), was 0.07. The genetic SD for DIFFcalf and DIFFcalf_ratio was 16.66 kg and 0.02, respectively. The direct and maternal heritability estimated for DIFFcalf was 0.28 (SE = 0.04) and 0.11 (SE = 0.02), respectively, and for DIFFcalf_ratio was 0.24 (SE = 0.04) and 0.17 (SE = 0.03), respectively. The genetic SD for DIFFdam was 47.09 kg; the direct heritability was 0.50 (SE = 0.03), and the dam repeatability was 0.75 (SE = 0.01). The genetic SD for RATIOcalfdam was 0.03; the direct and maternal heritability was 0.24 (SE = 0.04) and 0.24 (SE = 0.03), respectively. The suggested traits outlined in the present study provide useful metrics for benchmarking dam–calf efficiency; in addition, the genetic variability detected in these traits suggest genetic progress for more efficient dam–calf pairs is indeed possible.
Awareness ofandawareness that: their combination and dynamics
Authors: Fernández-Fernández Claudia , Velázquez-Quesada Fernando R 
Published: October 2019

AbstractThe paper proposes a logical framework representing the notion of explicit knowledge as the combination of awareness of and awareness that. The setting, semantically combining neighbourhood models with ideas from awareness logic, separates the mere fact of entertaining some information (being aware of $\varphi$) from the acknowledgement that the information is indeed the case (being aware that $\varphi$ holds). The text discusses not only the main properties these concepts obtain under the given representation, but also several of the epistemic actions that can be defined, and the way they affect the agent’s awareness (and thus her knowledge).
Winter activity patterns of the North American badger (Taxidea taxus) at its northwestern periphery
Authors: Symes Stephen A , Klafki Richard , Packham Roger , Larsen Karl W 
Published: October 2019

Abstract
The North American badger (Taxidea taxus) is a nonhibernating carnivore that occurs in areas with highly seasonal climates, such as in Canada where the animal reaches its northern limits. There, winter climate is harsh and conventional habitat is limited and patchy, possibly leading to additional energetic constraints. Using radiotelemetry and remote cameras, we documented winter activities of 16 badgers (12 females, 4 males) between 2007 and 2011 in British Columbia, at the northwestern periphery of the species’ range. In comparison to their summer ecology, the animals reduced home range sizes by up to 98% and showed fidelity to particular burrows. Burrow fidelity was variable (mean 27 days; range 0–108) and coincided with reduction in body temperatures, suggesting the onset of torpor. Despite lengthy use of the same burrow, badgers emerged frequently and conducted excursions that appeared to represent foraging behavior. Burrow emergence was not related to ambient temperature or snow depth; rather, it was best explained by the amount of days elapsed since the start of winter. Despite these trends, winter activity also was variable among individual badgers. It may be that limited fat reserves and higher energetic costs in northwestern ranges require winter foraging activities.
Transanal-only Swenson-like pull-through for late diagnosed Hirschsprung disease
Authors: Rentea Rebecca M , Halleran Devin R , Ahmad Hira , Maloof Elias , Wood Richard J , Levitt Marc A 
Published: October 2019

Abstract
Hirschsprung disease (HD) is an obstructive colonic process usually diagnosed in the neonatal period. A small subset of cases are diagnosed late, present with severe constipation without enterocolitis and have low rectosigmoid disease. A transanal-only pull-through is a well-described approach but in the newborn period risks a situation whereby the transition zone is higher than the sigmoid. We present our experience with the unique patient population of older HD patients in whom the transition zone was reliably reachable via a single-stage transanal approach, performed in prone position. Patients between 2 and 6 years of age with a rectal or sigmoid transition zone and minimal proximal colonic dilation can undergo a primary transanal pull-through surgical approach.
A rare presentation of an ectopic kidney with pyelonephritis mimicking appendicitis
Authors: Xu Yaying Eileen , Hendahewa Rasika 
Published: October 2019

Abstract
Acute appendicitis is one of the top differential diagnoses of right lower quadrant pain in the emergency department. There are many other conditions that may mimic appendicitis such as diverticulitis, colitis and gynecological conditions. We report a rare diagnosis of a patient who presents with characteristic clinical and laboratory features of appendicitis with severe sepsis, but later showed acute pyelonephritis of a malrotated right ectopic kidney on computer tomography. An ectopic kidney is very rare with an incidence of 1 in 3000. It is usually asymptomatic, although it may also associate with obstruction, infection and urolithiasis. This case report raises the importance of early recognition of the correct diagnosis using imaging in appropriate clinical settings, and prompt antibiotic treatment can avoid unnecessary surgical intervention, preserve renal function and prevent a life-threatening catastrophe.
Equal Opportunities in Newcomb’s Problem and Elsewhere
Authors: Ahmed Arif 
Published: October 2019

Abstract
The paper discusses Ian Wells’s recent argument (Wells 2019) that there is a decision problem in which followers of Evidential Decision Theory end up poorer than followers of Causal Decision Theory despite having the same opportunities for money. It defends Evidential Decision Theory against Wells’s argument, on the following grounds. (i) Wells's has not presented a decision problem in which his main claim is true. (ii) Four possible decision problems can be generated from his central example, in each of which followers of Evidential Decision Theory do at least as well as followers of Causal Decision Theory (but the former typically have better opportunities for money). (iii) There is another case in which followers of Causal Decision Theory have the same opportunities for making money but end up worse than followers of Evidential Decision Theory.
A survey for high-mass eclipsing binaries
Authors: Pozo Nuñez F , Chini R , Barr Domínguez A , Fein Ch , Hackstein M , Pietrzyński G , Murphy M 
Published: October 2019

ABSTRACT
We report results from a search for Galactic high-mass eclipsing binaries. The photometric monitoring campaign was performed in Sloan r and i with the robotic twin refractor RoBoTT at the Universitätssternwarte Bochum in Chile and complemented by Johnson UBV data. Comparison with the SIMBAD data base reveals 260 variable high-mass stars. Based on well-sampled light curves, we discovered 35 new eclipsing high-mass systems and confirm the properties of six previously known systems. For all objects, we provide the first light curves and determine orbital periods through the Lafler–Kinman algorithm. Apart from GSC 08173-0018 and Pismis 24-13 ($P = 19.47\, d$ and $20.14\, d$) and the exceptional short-period system TYC 6561-1765-1 ($P = 0.71\, d$), all systems have orbital periods between 1 and 9 d. We model the light curves of 26 systems within the framework of the Roche geometry and calculate fundamental parameters for each system component. The Roche lobe analysis indicates that 14 systems have a detached geometry, while 12 systems have a semidetached geometry; seven of them are near-contact systems. The deduced mass ratios q = M2/M1 reach from 0.4 to 1.0 with an average value of 0.8. The similarity of masses suggests that these high-mass binaries were created during the star formation process rather than by tidal capture.
Ultra-luminous quasars at redshift z &gt; 4.5 from SkyMapper
Authors: Wolf Christian , Hon Wei Jeat , Bian Fuyan , Onken Christopher A , Alonzi Noura , Bessell Michael A , Li Zefeng , Schmidt Brian P , Tisserand Patrick 
Published: October 2019

ABSTRACT
The most luminous quasars at high-redshift harbour the fastest growing and most massive black holes in the early Universe. They are exceedingly rare and hard to find. Here, we present our search for the most luminous quasars in the redshift range from z = 4.5 to 5 using data from SkyMapper, Gaia, and WISE. We use colours to select likely high-redshift quasars and reduce the stellar contamination of the candidate set with parallax and proper motion data. In ∼12 500 deg2 of Southern sky, we find 92 candidates brighter than Rp = 18.2. Spectroscopic follow-up has revealed 21 quasars at z ≥ 4 (16 of which are within z = [4.5, 5]), as well as several red quasars, Broad-Absorption-Line (BAL) quasars and objects with unusual spectra, which we tentatively label OFeLoBALQSOs at redshifts of z ≈ 1 to 2. This work lifts the number of known bright z ≥ 4.5 quasars in the Southern hemisphere from 10 to 26 and brings the total number of quasars known at Rp &lt; 18.2 and z ≥ 4.5 to 42.
miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database
Authors: Kehl Tim , Kern Fabian , Backes Christina , Fehlmann Tobias , Stöckel Daniel , Meese Eckart , Lenhof Hans-Peter , Keller Andreas 
Published: October 2019

AbstractSince the initial release of miRPathDB, tremendous progress has been made in the field of microRNA (miRNA) research. New miRNA reference databases have emerged, a vast amount of new miRNA candidates has been discovered and the number of experimentally validated target genes has increased considerably. Hence, the demand for a major upgrade of miRPathDB, including extended analysis functionality and intuitive visualizations of query results has emerged. Here, we present the novel release 2.0 of the miRNA Pathway Dictionary Database (miRPathDB) that is freely accessible at https://mpd.bioinf.uni-sb.de/. miRPathDB 2.0 comes with a ten-fold increase of pre-processed data. In total, the updated database provides putative associations between 27 452 (candidate) miRNAs, 28 352 targets and 16 833 pathways for Homo sapiens, as well as interactions of 1978 miRNAs, 24 898 targets and 6511 functional categories for Mus musculus. Additionally, we analyzed publications citing miRPathDB to identify common use-cases and further extensions. Based on this evaluation, we added new functionality for interactive visualizations and down-stream analyses of bulk queries. In summary, the updated version of miRPathDB, with its new custom-tailored features, is one of the most comprehensive and advanced resources for miRNAs and their target pathways.
Human Biomarker Exposure From Cigarettes Versus Novel Heat-Not-Burn Devices: A Systematic Review and Meta-Analysis
Authors: Drovandi Aaron , Salem Saad , Barker Daniel , Booth Debbie , Kairuz Therese 
Published: October 2019

AbstractIntroductionNovel tobacco products require independent research to assess their safety. This study assessed the current literature for trials comparing levels of biomarkers of exposure (BoE) between conventional cigarettes (CC) and heat-not-burn (HNB) devices.MethodsTen databases were searched using terms including: “heat not burn,” “iqos,” “teeps,” “mrtp,” “tobacco heating,” and “glo” between January 1, 2010 and August 13, 2019. Randomized controlled trials (RCTs) assessing comparative BoE levels in humans using either CC or novel HNB devices were eligible. BoE were tabulated, and differences between the intervention and control groups were analyzed and combined using a random-effects meta-analysis.ResultsTen nonblinded, RCTs were eligible, involving a total of 1766 participants. Studies regularly reported on 12 BoE (including nicotine). HNB devices assessed included the “IQOS” and “glo” devices and “precursor” (being developed) HNB devices. In comparison to CC, all 12 BoEs assessed were significantly lower for participants assigned to an HNB device. In comparison to smoking abstinence, HNB devices were statistically equivalent for eight BoEs and significantly elevated for four BoEs.ConclusionsThis review found that the potential for harm to humans is reduced when using HNB devices compared to CC as indicated by significant reductions in BoE levels. Whilst these results support tobacco manufacturer claims of improved safety, the small number of studies included, limited range of BoE assessed, and involvement of the tobacco industry necessitate further independent research to confirm the HNB devices as being a safer alternative to CC.ImplicationsThis study supports claims made by tobacco manufacturers on the improved safety of HNB tobacco devices in comparison to CC. These novel devices lead to reduced exposure to key biomarkers, which are linked to the health consequences attributed to tobacco use. This has strong implications for international public health as well as further research and policy development relating to the safety aspects and legalities of novel tobacco products.
Risk of Recurrent Staphylococcus aureus Prosthetic Joint Infection in Rheumatoid Arthritis Patients—A Nationwide Cohort Study
Authors: Singh Namrata , Nair Rajeshwari , Goto Michihiko , Carvour Martha L , Carnahan Ryan , Field Elizabeth H , Lenert Petar , Vaughan-Sarrazin Mary , Schweizer Marin L , Perencevich Eli N 
Published: October 2019

AbstractBackgroundTreatment of rheumatoid arthritis (RA) often involves immune-suppressive therapies. Concern for recurrent prosthetic joint infection (PJI) in RA patients might be high and could reduce use of joint implantation in these patients. We aimed to evaluate the risk of recurrence of PJI in RA patients compared with osteoarthritis (OA) patients by utilizing a large health care system.MethodsWe conducted a retrospective cohort study of all patients admitted for a Staphylococcus aureus PJI who underwent debridement, antibiotics, and implant retention (DAIR) or 2-stage exchange (2SE) between 2003 and 2010 at 86 Veterans Affairs Medical Centers. Both RA patients and the comparison group of osteoarthritis (OA) patients were identified using International Classification of Diseases, Ninth Revision, codes. All index PJI and recurrent positive cultures for S. aureus during 2 years of follow-up were validated by manual chart review. A Cox proportional hazards regression model was used to compare the time to recurrent PJI for RA vs OA.ResultsIn our final cohort of 374 veterans who had either DAIR or 2SE surgery for their index S. aureus PJI, 11.2% had RA (n = 42). The majority of the cohort was male (97.3%), and 223 (59.6%) had a methicillin-susceptible S. aureus PJI. RA patients had a similar risk of failure compared with OA patients, after adjusting for covariates (hazard ratio, 0.81; 95% confidence interval, 0.48–1.37).ConclusionsPrior diagnosis of RA does not increase the risk of recurrent S. aureus PJI. Further studies are needed to evaluate the effect of different RA therapies on outcomes of episodes of PJI.
Relation of FTO to BOLD response to receipt and anticipated receipt of food and monetary reward, food images, and weight gain in healthy weight adolescents
Authors: Stice Eric , Yokum Sonja , Voelker Pascale 
Published: October 2019

Abstract
Although the fat mass and obesity-associated gene (FTO) correlates with elevated body mass, it is unclear how it contributes to overeating. We tested if individuals with the A allele show greater reward region responsivity to receipt and anticipated receipt of food and money and palatable food images. We also tested if these individuals show greater future weight gain. Initially healthy weight adolescents (Study 1, N = 162; Study 2, N = 135) completed different functional magnetic resonance imaging paradigms and had their body mass measured annually over 3 years. Adolescents with the AA or AT genotypes showed less precuneus and superior parietal lobe response and greater cuneus and prefrontal cortex response to milkshake receipt and less putamen response to anticipated milkshake receipt than those with the TT genotype in separate analyses of each sample. Groups did not differ in response to palatable food images, and receipt and anticipated receipt of money, or in weight gain over 3-year follow-up. Results suggest that initially healthy weight adolescents with vs without the FTO A allele show differential responsivity to receipt and anticipated receipt of food but do not differ in neural response to palatable food images and monetary reward and do not show greater future weight gain.
Demographics, sleep, and daily patterns of caffeine intake of shift workers in a nationally representative sample of the US adult population
Authors: Lieberman Harris R , Agarwal Sanjiv , Caldwell John A , Fulgoni Victor L 
Published: October 2019

Abstract

Study Objective
Caffeine is the most widely consumed stimulant in the world, and sociodemographic factors including occupation are associated with intake. Shift work, required in various occupations, is associated with poor sleep, inadequate diet, and adverse health effects. Using a large nationally representative database, demographics, sleep, and caffeine intake of US adults working various shifts were assessed.

Methods
The 24-hour dietary recall data from NHANES 2005–2010 (N = 8,500) were used to estimate caffeine intake from foods and beverages. Work shifts were self-reported as follows: regular day shift; evening shift; night shift; rotating shift; or other shift. Regression analyses assessed associations of shift work with caffeine intake after adjustment for sociodemographic factors.

Results
Approximately 74% of employed adults were day-shift workers and 26% were nonday-shift workers. Night-shift workers slept for 6.25 ± 0.09 hours per day, somewhat less than day-shift workers who only slept 6.83 ± 0.02 hours (p < .0001). Mean 24-hour weekday caffeine intake of evening-, night-, and rotating-shift workers (217 ± 23, 184 ± 19, and 206 ± 15 mg, respectively) was similar (p > .3) to day-shift workers (203 ± 5 mg). Regardless of work schedule, individuals consumed the most caffeine during morning hours. Evening- and night-shift workers reported consuming 36%–46% less caffeine during their work hours and 72%–169% more during nonwork hours than day-shift workers (p < .01).

Conclusions
Total daily caffeine intake of shift workers is similar to nonshift workers; most caffeine is consumed in the morning regardless of shift. Because shift workers consume less caffeine during regular work hours and more during nonwork hours than day workers, they may be using caffeine to, in part, optimize off-duty alertness.
Smoking cessation avatar-led Acceptance and Commitment Therapy digital intervention: feasibility and acceptability in young adults
Authors: Karekla Maria , Savvides Stella Nicoleta 
Published: October 2019

Abstract
Smoking remains a global concern especially among youth and smoking cessation interventions have not been particularly successful with this age group. The aim of the present study was to evaluate the feasibility and acceptability of an innovative avatar-led, digital intervention grounded in Acceptance and Commitment Therapy (ACT) for smoking cessation in youth. Participants were 49 university student smokers, aged 18–28 years old (Mage = 22.50, SD = 2.56; 64.3% females). Participants found the program satisfactory, useful, and motivating. Participants enjoyed the digitally unique components of the intervention, such as videos, metaphors, and games, more than the overall graphics and the appearance of the avatars. Results of this study are encouraging for the acceptability and satisfaction with avatar-led digitized ACT interventions for smoking cessation targeting young smokers. Participants suggested that future program advances should include a more reality-based user experience and more interactive avatars. Future adaptations should consider additional ways to decrease attrition rates and further increase satisfaction and motivation to complete the program and quit smoking.