bluuebunny/crossref_metadata_2025_split huggingface dataset:
Data Mining Approaches for Assessing Chemical Coexposures Using Consumer Product Purchase Data
Authors: Tornero‐Velez Rogelio , Isaacs Kristin , Dionisio Kathie , Prince Steven , Laws Hanna , Nye Michael , Price Paul S. , Buckley Timothy J. 
Published: December 2020

AbstractThe use of consumer products presents a potential for chemical exposures to humans. Toxicity testing and exposure models are routinely employed to estimate risks from their use; however, a key challenge is the sparseness of information concerning who uses products and which products are used contemporaneously. Our goal was to demonstrate a method to infer use patterns by way of purchase data. We examined purchase patterns for three types of personal care products (cosmetics, hair care, and skin care) and two household care products (household cleaners and laundry supplies) using data from 60,000 households collected over a one‐year period in 2012. The market basket analysis methodology frequent itemset mining (FIM) was used to identify co‐occurring sets of product purchases for all households and demographic groups based on income, education, race/ethnicity, and family composition. Our methodology captured robust co‐occurrence patterns for personal and household products, globally and for different demographic groups. FIM identified cosmetic co‐occurrence patterns captured in prior surveys of cosmetic use, as well as a trend of increased diversity of cosmetic purchases as children mature to teenage years. We propose that consumer product purchase data can be mined to inform person‐oriented use patterns for high‐throughput chemical screening applications, for aggregate and combined chemical risk evaluations.
Anti-Resonance Frequency Control by Span-Tuning Dynamic Vibration Absorber for Brush Cutter Vibration Reduction
Authors: Koike Yuki , Tsuruoka Shingo 
Published: December 2020

Abstract
Significant handle vibrations often occur during mowing operation even with anti-vibration type brush cutters. This is often caused by combined-bending natural mode of the main pipe and driveshaft which is mainly excited by cutting head rotational force. In this study, we focused on the placement span of the rubber bushings that support the driveshaft to suppress this kind of resonance. More specifically, we have designed a new component, called a span-tuning dynamic vibration absorber (ST-DVA), which utilizes the bending mode of the driveshaft that is determined by the placement span of rubber bushings. Analysis results of the finite element method (FEM) showed that the ST-DVA generated anti-resonance at a specific point on the main pipe under the first-order inertial force of the cutting head. We also succeeded in controlling anti-resonance frequency under the excitation. In actual measurements at the target frequency, handle vibration of the first-order component of the cutting head could be reduced by 51% and overall handle vibration could be reduced by 49% compared with those produced via equal-span rubber bushing placement. Hence, our study provides a design method that makes it possible to utilize the driveshaft, which a primary brush cutter component, as a dynamic vibration absorber by altering the placement span of the rubber bushings.
Landlocked Atlantic salmon in a large river–lake ecosystem: managing an endemic, large-bodied population of high conservation value
Authors: Greenberg Larry A. , Norrgård Johnny R. , Gustafsson Pär , Bergman Eva 
Published: December 2020

Managing and conserving threatened migratory salmonid populations in large river–lake ecosystems is challenging not only because of the ecosystems’ large size, but also because there is often more than one anthropomorphic stressor. The River Klarälven – Lake Vänern ecosystem, situated in Norway and Sweden, is a large, highly modified ecosystem, home to a threatened, endemic, large-bodied population of landlocked Atlantic salmon (Salmo salar). With 11 dams, the salmon population has been maintained through extensive stocking and a truck and transport system for spawners. Here we review what we have learned about the salmon after 15 years of research, highlighting the major findings for each life stage. Our studies indicate that the salmon population is below carrying capacity, and we suggest measures to increase the number of spawners and downstream passage success. Habitat restoration to compensate for losses from former log-driving activities is expected to further increase carrying capacity. Re-establishing salmon in Klarälven’s upper reaches in Norway, while possible, is fraught with both ecological and legislative hurdles. Substantial long-term funding is needed to foster co-management and ensure a sustainable fishery.
The special point on the hybrid star mass–radius diagram and its multi–messenger implications
Authors: Cierniak Mateusz , Blaschke David 
Published: December 2020

AbstractWe show the existence and investigate the location of the special point (SP) in which hybrid neutron star mass-radius (M-R) curves have to cross each other when they belong to a class of hybrid equation of state (EoS) constructed with generic constant–speed–of–sound (CSS) quark matter models for which the onset deconfinement is varied. We demonstrate that for a three-parameter CSS model the position of the SP in the M-R diagram is largely independent of the choice of the hadronic EoS, but in dependence on the stiffness of the quark matter EoS it spans a region that we identify. We find that the difference between the maximum mass and the SP mass depends on the mass at the onset of deconfinement so that an upper limit of 0.19 M⊙for this difference is obtained from which a lower limit on the radius of hybrid stars is deduced. Together with a lower limit on the radius of hadronic stars, derived from a class of reasonably soft hadronic EoS including hyperons, we identify a region in the M-R diagram which can be occupied only by hybrid stars. Accordingly, we suggest that a NICER radius measurement on the massive pulsar PSR J0740 + 6620 in the range of 8.6-11.9 km would indicate that this pulsar is a hybrid neutron star with deconfined quark matter in the inner core.
An Immune Risk Score Predicts Survival of Patients with Acute Myeloid Leukemia Receiving Chemotherapy
Authors: Wang Yun , Cai Yan-yu , Herold Tobias , Nie Run-cong , Zhang Yu , Gale Robert Peter , Metzeler Klaus H. , Zeng Yun , Wang Shun-qing , Pan Xue-yi , Yang Tong-hua , Wu Yuan-bin , Zhang Qing , Wuxiao Zhi-jun , Du Xin , Liang Zhi-wei , Su Yong-zhong , Xu Jing-bo , Wang Yong-qing , Liu Ze-lin , Wu Jian-wei , Zhang Xiong , Wu Bing-yi , Xiao Ruo-zhi , Wang San-bin , Li Jin-yuan , Chi Pei-dong , Zhang Qian-yi , Chen Si-liang , Qin Zhe-yuan , Zhang Xin-mei , Zhong Na , Hiddemann Wolfgang , Liu Qi-fa , Zhang Bei , Liang Yang 
Published: December 2020

AbstractPurpose:Prediction models for acute myeloid leukemia (AML) are useful, but have considerable inaccuracy and imprecision. No current model includes covariates related to immune cells in the AML microenvironment. Here, an immune risk score was explored to predict the survival of patients with AML.Experimental Design:We evaluated the predictive accuracy of several in silico algorithms for immune composition in AML based on a reference of multi-parameter flow cytometry. CIBERSORTx was chosen to enumerate immune cells from public datasets and develop an immune risk score for survival in a training cohort using least absolute shrinkage and selection operator Cox regression model.Results:Six flow cytometry–validated immune cell features were informative. The model had high predictive accuracy in the training and four external validation cohorts. Subjects in the training cohort with low scores had prolonged survival compared with subjects with high scores, with 5-year survival rates of 46% versus 19% (P &lt; 0.001). Parallel survival rates in validation cohorts-1, -2, -3, and -4 were 46% versus 6% (P &lt; 0.001), 44% versus 18% (P = 0.041), 44% versus 24% (P = 0.004), and 62% versus 32% (P &lt; 0.001). Gene set enrichment analysis indicated significant enrichment of immune relation pathways in the low-score cohort. In multivariable analyses, high-risk score independently predicted shorter survival with HRs of 1.45 (P = 0.005), 2.12 (P = 0.004), 2.02 (P = 0.034), 1.66 (P = 0.019), and 1.59 (P = 0.001) in the training and validation cohorts, respectively.Conclusions:Our immune risk score complements current AML prediction models.
Putting on Christ
Authors: Glodt Julie 
Published: December 2020

Abstract
In medieval Christendom, liturgical vestments were not just attributes for priestly identity. In direct contact with the celebrant’s body, they were charged with numerous allegorical significations that this article is aimed at studying. The first one associated the priest’s clothing with a moral “rite of passage.” Each vestment symbolized a virtue, thanks to which the priest was supposed to get ready for the Mass. A new allegorical system emerged in the thirteenth century: as symbols of arma Christi, the vestments invited the priest to follow Christ in his Passion. These liturgical garments were even considered as metaphors for Christ’s flesh. Towards the end of the Middle Ages, the celebrant’s clothing was a kind of new embodiment. By putting the liturgical vestments on, the priest was able to transform into the ultimate priest with a new emphasis on his quasi-demiurgic power; as such the priest became one of the most sacred components of the ritual of the Eucharist.
“Like a doll …”
Authors: Pereira Diana 
Published: December 2020

Abstract
In the 1990s there was a growing and renewed interest on the practice of clothing images of saints after, as Richard Trexler put it, the negligence demonstrated towards it by art historians until then. In 2018, following the publication of new and unprejudiced studies about it, the presence of two dresses belonging to statues of the Virgin Mary in the Metropolitan Museum of Art’s exhibition “Heavenly Bodies: Fashion and the Catholic Imagination” testified to the impact clothed images had on fashion creators and, according to David Morgan, the Church’s ritual and performative life. While focusing on the miraculous image of Nossa Senhora da Lapa from Quintela, Portugal, this article aims to acknowledge the many roles played by its clothes and jewels, assessing the complexity of this phenomenon and aiming for a wider understanding of how the faithful engaged with devotional sculpture.
Indigenizing Self-Determination at the United Nations: Reparative Progress in the Declaration on the Rights of Indigenous Peoples
Authors: Johnson Miranda 
Published: December 2020

Abstract
When the United Nations General Assembly passed the Declaration on the Rights of Indigenous Peoples in 2007, it introduced into the international legal lexicon a new dimension to the concept of self-determination. The declaration emphasizes indigenous peoples’ distinctive rights to land, culture, language, and collective identity. It does not propose political independence or sovereign statehood, instead insisting on indigenous peoples’ equal rights of citizenship within existing nation-states. The distinct dimension of self-determination that the declaration introduces is one that speaks of indigenous peoples’ particular colonial histories of dispossession and the restoration of their rights and identities in the present, but without disrupting the political continuity of the states that surround them. It is reparative rather than revolutionary. In this article, I examine the construction and contestation of an indigenous right to self-determination both in relation to earlier definitions, and among and between the peoples and states who drafted the declaration.
Introducing Philosophy to the Classroom in the Sixth Century CE
Authors: d’Hoine Pieter 
Published: December 2020

Abstract
Taking the recent publication of Sebastian Gertz’ translation of three late Platonic Introductions by Elias, David and Olympiodorus as a starting point, this review paper provides an assessment of Gertz’ translation and textual choices. In addition, it also provides an original contribution to the study of these texts by proposing an emendation of David’s text, and by discussing some of the source-texts of the three Introductions and of their parallels in the ancient commentary tradition. One case elaborated on in somewhat greater detail concerns Olympiodorus’ arguments against scepticism.
由文例對比論卜辭「其—祭牲」的句意
Authors: 朱 歧祥 
Published: December 2020

摘要
本論文強調使用比較方法研究甲骨文的語法，就甲骨談甲骨。一是先由常態的句型分析，對比變異句型的產生原因和彼此的差異，而不是直接由變異句型入手去拆句子; 一是由早期句型分析，透過句型流變來了解晚出句型的特性，而不是單獨的由晚出句例看問題。這種反覆對比的觀察，才能客觀掌握甲文句型的具体用意。本文以晚期卜辭單獨應用的「其—祭牲」句為例，對比大量歲字句的用法，發現它是源出自歲字類祭祀卜辭。正確的理解這類句型，是句前省略了歲字類句意的祭祀陳述句，句後又省略了卜問祭祀宜否、時王安否或雨否等的詢問句，只保留著中間的一段陳述分句。這是目前所見簡略的「其一祭牲」句作為變異句型的演變過程。
Evaluation of the usability of various rapid antibody tests in the diagnostic application for COVID-19
Authors: Uwamino Yoshifumi , Wakui Masatoshi , Aoki Wataru , Kurafuji Toshinobu , Yanagita Emmy , Morita Maasa , Nagata Mika , Inose Rika , Noguchi Masayo , Yokota Hiromitsu , Hasegawa Naoki , Saya Hideyuki , Murata Mitsuru ,   for the Keio Donner Project Team
Published: December 2020

Background The usability of laboratory tests related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critically important for the world undergoing the COVID-19 pandemic. The present study aimed to assess the diagnostic usability of rapid tests for the detection of antibody against SARS-CoV-2 through comparison of their results with the results of reverse transcription polymerase chain reaction (RT-PCR) test for the detection of SARS-CoV-2 genomic RNA and with the results of a quantitative test for antibody detection. Methods Serum samples were collected from 18 patients undergoing RT-PCR testing for SARS-CoV-2. Twelve patients were RT-PCR positive while six were negative. A quantitative test based on chemiluminescent immunoassay and three rapid tests based on immunochromatography were performed to detect anti-SARS-CoV-2 IgG and IgM. Results All the antibody tests exhibited poor sensitivity at the timing of initial RT-PCR diagnosis. IgG responses occurring prior to or simultaneously with IgM responses were observed through not only the quantitative test but also the three rapid tests. Based on concordance with the quantitative test results, the large variance among the three rapid tests was revealed. Conclusions All antibody tests were unsatisfactory to replace RT-PCR for the early diagnosis of COVID-19. Rapid antibody tests as well as a quantitative antibody test were useful in the assessment of immune responses in COVID-19. The obvious variance among the three rapid tests suggested limited accuracy and difficult standardization. Diagnostic usability of rapid antibody tests for COVID-19 should be investigated rigorously.
Long-term course after pediatric right ventricular outflow tract reconstruction
Authors: Junnil Pimchanok , Cheanvechai Chalit , Namchaisiri Jule , Saprungruang Ankavipar , Thitivaraporn Puwadon , Chomvilailuk Mueanthep , Benjacholamas Vichai 
Published: December 2020

Objectives Valved homografts are commonly used for right ventricular outflow tract reconstruction. However, despite good early results, they lack durability. This study was designed to compare single-center results of implantation of 3 types of right ventricular outflow tract conduit, in terms of patient survival, graft failure, reoperation, and risk factors for reoperation. Methods One hundred and forty-three pediatric patients who underwent right ventricular outflow tract conduit implantation between January 2006 and December 2018 were reviewed. We stratified conduits by aortic, pulmonic homograft, and Contegra; 74 aortic homografts, 61 pulmonic homografts, and 8 Contegra conduits were implanted. Median age at implantation was 3 years. The primary diagnosis was truncus arteriosus in 41.3%. We analyzed the role of sex, age, diagnosis, and graft size. Endpoints included freedom from graft failure, freedom from reoperation, and survival. Results The survival rate was 83.2% at 10 years. Freedom from graft failure at 2, 5, and 10 years was 100%, 97.9%, and 63.4%, respectively. Freedom from reoperation was 85.8% for pulmonic homografts and 74.9% for aortic homografts at 10 years, and 100% for Contegra at 6 years. Multivariable analysis identified conduit diameter <18 mm as a risk factor for reoperation (hazard ratio: 3.16, 95% confidence interval: 1.38–7.23, p = 0.007). Conclusion Homograft valves used for right ventricular outflow tract reconstruction provided excellent long-term durability and late survival. The only factor that adversely affected graft longevity was small graft size (diameter <18 mm). Reoperation for conduit failure was not significantly different among the groups.
A Novel Parent Questionnaire for the Detection of Seizures in Children of Spanish-Speaking Families
Authors: Torres Alcy R. , Camayd-Muñoz Cristina , Alvarado Manuel Christian , Perez Brandon , Pou Jonathan , Hereen Timothy , Jonas Rinat , Douglass Laurie M. 
Published: December 2020

Background: We developed and validated a Spanish seizure screen for children based on a previously validated English seizure screen that could be administered by a trained research assistant in a 2-step process, approximating the clinical diagnostic process of a pediatric epilepsy specialist. This questionnaire was designed to study seizure prevalence in a research population of children at risk for epilepsy. Methods: Spanish-speaking parents of children 6 months to 17 years old were recruited from the pediatric neurology clinics at Boston Medical Center and interviewed using a computerized questionnaire. A computerized algorithm of parent responses rendered a seizure classification of positive or negative. Blinded to questionnaire results, pediatric neurologists served as the diagnostic gold standard, ranking each patient event using a 4-level scale based on clinical history and examination: (1) not likely, (2) indeterminate, (3) probable, and (4) almost certain where rankings of 3 or 4 lead to a diagnosis of seizure. Results: The questionnaire was completed by 163 enrolled parents. The seizure screen demonstrated a 94.2% sensitivity and 93.7% specificity for identifying seizures. The positive predictive value was 87.5%, and the negative predictive value was 97.2%. Conclusions: This pediatric seizure questionnaire was both sensitive and specific for detecting clinically confirmed seizures. This tool may be useful to clinicians and researchers in screening large populations of children, decreasing the time and cost of added neurologic assessments.
Local Ketorolac Injection vs Popliteal Sciatic Nerve Blockade as an Adjuvant to a Spinal Block in Hindfoot Arthrodesis
Authors: Chuckpaiwong Bavornrit , Harnroongroj Thos , Sirivanasandha Busara , Tharmviboonsri Theerawoot 
Published: December 2020

Background: Popliteal nerve blocks reduce pain and markedly improve postoperative outcomes during foot and ankle surgery; however, several potential complications may arise from nerve block procedures. The purpose of this study was to investigate local infiltration analgesia with ketorolac as a convenient alternative for pain relief. Methods: A total of 80 patients scheduled for hindfoot arthrodesis were randomly allocated to one of 2 anesthetic groups: a spinal block augmented with either a popliteal nerve block (n = 40) or local ketorolac and Marcaine infiltration (n = 40). Clinical assessment included postoperative visual analog scale (VAS) pain scores at 4, 8, 12, 24, and 48 hours, total morphine consumption, time to incision (time in operating room to incision), operative time, length of hospital stay, and complications. Results: Despite similar morphine consumption between groups ( P = .28), VAS scores were significantly lower at 24 hours (1.6 ± 2.2 cm vs 2.7 ± 3.0 cm, P = .01) and 48 hours (0.2 ± 0.7 cm vs 1.0 ± 1.5 cm, P < .01) after surgery using local ketorolac injection. Although time from entry into the operating room to incision was also reduced after local ketorolac injection (19.0 ± 5.3 minutes vs 31.4 ± 14.6 minutes, P < .001), the length of operative time ( P = .38), hospital stay ( P = .43), and number of complications ( P = .24) were similar between groups. Conclusion: Ketorolac local injection provided effective pain control in hindfoot arthrodesis and markedly reduced VAS pain scores up to 48 hours after surgery compared with popliteal nerve block. In addition, ketorolac local injection also reduced time in the operating room compared with popliteal nerve blockade. Level of Evidence: Level 1, randomized controlled trial.
Broadening perfect sound absorption by composite absorber filled with porous material at low frequency
Authors: Cheng Baozhu , Gao Nansha , Huang Yunke , Hou Hong 
Published: December 2020

To enhance the low-frequency broadband sound absorption, we propose an absorber filled with porous material and establish a relative acoustic model. Based on the critical coupling condition, a Helmholtz absorber was designed to achieve perfect sound absorption at 172 Hz by the complex frequency plane method. Considering the weak adjustability and acoustic impedance of the Helmholtz absorber, we devised four absorber filled with porous material units that can achieve perfect sound absorption at discrete frequencies between 400 and 488 Hz with a thickness of only 51 mm. A composite absorber filled with porous material was designed by arranging four absorber filled with porous material units in a coplanar manner. The broadband perfect sound absorption of the composite absorber filled with porous material was subsequently verified by simulation and experiment. The thickness of the composite absorber filled with porous material is only 1/18 of the wavelength corresponding to the perfect absorption frequency, and it shows excellent subwavelength characteristics. The theoretical acoustic model of the composite absorber filled with porous material and the complex frequency plane method can achieve a more efficient design of broadband perfect sound absorbers. The composite absorber filled with porous material not only realizes low-frequency broadband perfect sound absorption but is also lightweight and easy to fabricate. This demonstrates the composite absorber filled with porous material structure has great potential for application in low to mid frequency noise control.