bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of the Family’s Emotional Climate in the Links between Parent-Adolescent Communication and Adolescent Psychosocial Functioning
Authors: Kapetanovic Sabina , Skoog Therése 
Published: September 2020

AbstractThe current study was designed to extend the parenting literature by testing the moderating role of the family’s emotional climate, operationalized with parent-adolescent emotional closeness and adolescent feelings of being overly controlled by parents on the longitudinal associations between parent-driven communication efforts (i.e. parental behavioral control and solicitation of information from their adolescent), adolescent-driven communication efforts (i.e. adolescent disclosure and secrecy) and adolescent psychosocial functioning (i.e. emotional problems, conduct problems, delinquency, and wellbeing). We conducted a series of cross-lagged models controlling for adolescent gender and ethnicity using a two-wave Swedish longitudinal set of self-report data (N = 1515, 51% girls, M age = 13.0 and 14.3 years at T1 and T2, respectively). Multi-group analyses revealed that the negative links between T1 parental control and T2 adolescent delinquency, T1 parental solicitation and T2 adolescent conduct problems and delinquency, and T1 emotional problems and T2 adolescent disclosure were moderated by the family’s emotional climate. When the family’s emotional climate was positive, the parenting strategies had a more positive effect on adolescent psychosocial functioning, and adolescents with emotional problems communicated more openly with their parents. These findings suggest that the relational context in the family is an important protective factor and add specificity to the previously established role of parent-adolescent communication in adolescent psychosocial development. In terms of preventive interventions, strategies to enhance the family’s emotional climate should be considered prior to teaching specific parenting strategies.
Mechanical loading of tissue engineered skeletal muscle prevents dexamethasone induced myotube atrophy
Authors: Aguilar-Agon Kathryn W. , Capel Andrew J. , Fleming Jacob W. , Player Darren J. , Martin Neil R. W. , Lewis Mark P. 
Published: September 2020

AbstractSkeletal muscle atrophy as a consequence of acute and chronic illness, immobilisation, muscular dystrophies and aging, leads to severe muscle weakness, inactivity and increased mortality. Mechanical loading is thought to be the primary driver for skeletal muscle hypertrophy, however the extent to which mechanical loading can offset muscle catabolism has not been thoroughly explored. In vitro 3D-models of skeletal muscle provide a controllable, high throughput environment and mitigating many of the ethical and methodological constraints present during in vivo experimentation. This work aimed to determine if mechanical loading would offset dexamethasone (DEX) induced skeletal muscle atrophy, in muscle engineered using the C2C12 murine cell line. Mechanical loading successfully offset myotube atrophy and functional degeneration associated with DEX regardless of whether the loading occurred before or after 24 h of DEX treatment. Furthermore, mechanical load prevented increases in MuRF-1 and MAFbx mRNA expression, critical regulators of muscle atrophy. Overall, we demonstrate the application of tissue engineered muscle to study skeletal muscle health and disease, offering great potential for future use to better understand treatment modalities for skeletal muscle atrophy.
Health-related stakeholders’ perceptions of clinical pharmacy services in Qatar
Authors: Jebara Tesnime , Cunningham Scott , MacLure Katie , Awaisu Ahmed , Pallivalapila Abdulrouf , Al Hail Moza , Stewart Derek 
Published: September 2020

AbstractBackground In Qatar, the National Vision 2030 and the National Health Strategy 2018–2022 articulate the need to improve healthcare delivery by better utilisation of the skilled workforce. In this regard, pharmacy practice is rapidly advancing and several extended pharmacy services are now available in institutionalised settings. Objective This study aimed to determine health-related stakeholders’ perceptions of current clinical pharmacy services in Qatar, and the potential development and implementation of further patient-centred roles. Setting All major organisations and institutions relating to the practice, education, regulation, and governance of pharmacy in Qatar. Method Qualitative, face-to-face semi-structured interviews were conducted with individuals in key strategic positions of policy development and influence (i.e. health-related academic leaders, healthcare policy developers, directors of medicine/pharmacy/nursing, and patient safety leaders). Participants were recruited via a combination of purposeful and snowball sampling, until the point of data saturation was reached. The interview guide was grounded in the Consolidated Framework for Implementation Research domains of innovation characteristics, outer and inner setting, characteristics of individuals, and implementation process. The interviews were digitally recorded, transcribed and independently analysed by two researchers using the Framework approach. Main outcome measure Perceptions of stakeholders regarding current and potential for future clinical pharmacy services in Qatar. Results Thirty-seven interviews were conducted with stakeholders of policy influence in healthcare. The interviewees reported a variety of clinical pharmacy services available in Qatar, which they perceived as positively impacting patient care outcomes, pharmacists’ professional autonomy, and the healthcare system in general (innovation characteristics). However, they perceived that these services were mainly performed in hospitals and less in community pharmacy setting (inner setting) and were undervalued by patients and the public (outer setting). Expansion of pharmacists’ clinical activities was supported, with recognition of facilitators such as the skillset and training of pharmacists, potential time release due to automation and well-considered implementation processes (characteristics of individuals, inner setting, process). Conclusion Health-related stakeholders in Qatar have positive perceptions of current clinical pharmacy services and support the expansion of pharmacist’s roles. However, service development needs to consider the issues of patient and public awareness and initially target institutionalised healthcare settings.
Understanding phase-transfer catalytic synthesis of fullerenol and its interference from carbon dioxide and ozone
Authors: Chokaouychai Sirikanya , Zhang Qi 
Published: September 2020

AbstractPhase-transfer catalytic reaction involving the use of tetrabutylammonium hydroxide (TBAH) as catalyst and sodium hydroxide (NaOH) solution as the source of hydroxide ions is among the popular choices for synthesis of fullerenol, the polyhydroxylated fullerene. To further understand the process, two experiments were conducted to preliminarily explore the influences of the amount of TBAH and NaOH, respectively, in terms of the achieved level of hydroxylation (i.e. number of hydroxyl groups per fullerenol molecule). The process responded to the variation of the amount of TBAH (over a twofold series of 3–192 drops, average volume 0.0223 ± 0.0004 ml per drop) in a nonlinear manner with a local maximum achieved from 24 drops TBAH (giving 13 OH groups) and a local minimum from 48 drops (giving 8 groups). To the variation of the amount of NaOH (over the range of 0.5–8.0 ml NaOH), the fitted function of the process response resembled Freundlich adsorption isotherm, with an initially increasing trend before levelling off at 4.0 ml NaOH (giving 15 OH groups). It is therefore suggested that fullerene hydroxylation could be explained by liquid–solid adsorption. In addition, it was found that ambient carbon dioxide led to the existence of sodium carbonate in the bulk of the collected product (although not chemically bound). It was also discovered that ambient ozone adversely affected fullerenol synthesis by converting C60 fullerene into fullerene epoxide (C60O). The affected syntheses thus produced epoxide-containing fullerenol instead.
Aerodynamic benefits for a cyclist by drafting behind a motorcycle
Authors: Blocken Bert , Malizia Fabio , van Druenen Thijs , Gillmeier Stefanie 
Published: September 2020

AbstractMotorcycles are present in cycling races for reasons including television broadcasting. During parts of the race, these motorcycles ride in front of individual or groups of cyclists. Concerns have been expressed in the professional cycling community that these motorcycles can provide aerodynamic benefits in terms of drag reduction for the cyclists drafting behind them. However, to the best of our knowledge, no information about the extent of these benefits is present in the scientific literature. Therefore, this paper analyses the potential drag reduction for a cyclist by drafting behind a motorcycle. Wind tunnel measurements and numerical simulations with computational fluid dynamics were performed. It was shown that drafting at separation distances d = 2.64, 10, 30 and 50 m can reduce the drag of the cyclist down to 52, 77, 88 and 93% of that of an isolated cyclist, respectively. A cyclist power model is used to convert these drag reductions into potential time gains. For a non-drafting cyclist at a speed of 54 km/h on level road in calm weather, the time gains by drafting at d = 2.64, 10, 30 and 50 m are 12.7, 5.4, 2.7 and 1.6 s per km, respectively. These time differences can influence the outcome of cycling races. The current rules of the International Cycling Union do not prevent these aerodynamic benefits from occurring in races.
Effect of starting materials and sintering temperature on microstructure and optical properties of Y2O3:Yb3+ 5 at% transparent ceramics
Authors: Yavetskiy R. P. , Balabanov A. E. , Parkhomenko S. V. , Kryzhanovska O. S. , Doroshenko A. G. , Mateychenko P. V. , Tolmachev A. V. , Li Jiang , Jiang Nan , Gheorghe L. , Enculescu M. 
Published: September 2020

AbstractY2O3:Yb3+ 5 at% ceramics have been synthesized by the reactive sintering method using different commercial yttria powders (Alfa-Micro, Alfa-Nano, and ITO-V) as raw materials. It has been shown that all Y2O3 starting powders consist from agglomerates up to 5–7 µm in size which are formed from 25–60 nm primary particles. High-energy ball milling allows to significantly decreasing the median particle size D50 below 500 nm regardless of the commercial powders used. Sintering experiments indicate that powder mixtures fabricated from Alfa-Nano yttria powders have the highest sintering activity, while (Y0.86La0.09Yb0.05)2O3 ceramics sintered at 1750 °C for 10 h are characterized by the highest transmittance of about 45%. Y2O3:Yb3+ ceramics have been obtained by the reactive sintering at 1750–1825°C using Alfa-Nano Y2O3 powders and La2O3+ZrO2 as a complex sintering aid. The effects of the sintering temperature on densification processes, microstructure, and optical properties of Y2O3:Yb3+ 5 at% ceramics have been studied. It has been shown that Zr4+ ions decrease the grain growth of Y2O3:Yb3+ ceramics for sintering temperatures 1750–1775 °C. Further increasing the sintering temperature was accompanied by a sharp increase of the average grain size of ceramics referred to changes of structure and chemical composition of grain boundaries, as well as their mobility. It has been determined that the optimal sintering temperature to produce high-dense yttria ceramics with transmittance of 79%–83% and average grain size of 8 µm is 1800 °C. Finally, laser emission at ∼1030.7 nm with a slope efficiency of 10% was obtained with the most transparent Y2O3:Yb3+ 5 at% ceramics sintered.
A comprehensive study on Li4Si1−xTixO4 ceramics for advanced tritium breeders
Authors: Gong Yichao , Liu Lin , Qi Jianqi , Yang Mao , Li Junjie , Wang Hailiang , Guo Hao , Zhang Guojun , Lu Tiecheng 
Published: September 2020

AbstractHetero-element doped lithium orthosilicates have been considered as advanced tritium breeders due to the superior performances. In this work, Li4Si1−xTixO4 ceramics were prepared by proprietary hydrothermal process and multistage reactive sintering. The reaction mechanism of Li4Si1−xTixO4 was put forward. XRD and SEM analyses indicate that insertion of Ti leads to lattice expansion, which promotes the grain growth and changes the fracture mode. The compressive tests show that the crush load increases almost four times by increasing x from 0 to 0.2. However, the thermal conductivity and ionic conductivity are the best when x = 0.05 and x = 0.1, respectively. Thermal cycling stability of Li4Si1−xTixO4 pebbles was further appraised through investigating the changes of microstructure and crush load. After undergoing thermal cycling, the Li4Si1−xTixO4 still show higher crush load compared with Li4SiO4, despite Ti segregation in some samples. The x = 0.05 sample exhibits excellent thermal cycling stability. In summary, proper amount of Ti doping can improve the crush load, thermal and ionic conductivity, and thermal cycling stability of Li4SiO4.
Precise Formation-Flying Telescope in Target-Centric Orbit: the Solar Case
Authors: Saint-Hilaire Pascal , Marchese Jeffrey E. 
Published: September 2020

AbstractWe present the general concept of a telescope with optics and detectors mounted on two separate spacecrafts, in orbit around the telescope’s target (scopocentric or target-centric orbit), and using propulsion to maintain the Target-Optics-Detector alignment and Optics-Detector distance. Specifically, we study the case of such a telescope with the Sun as the target, orbiting at $\sim $
∼
1 AU. We present a simple differential acceleration budget for maintaining Target-Optics-Detector alignment and Optics-Detector distance, backed by simulations of the orbital dynamics, including solar radiation pressure and influence of the planets. Of prime interest are heliocentric orbits (such as Earth-trailing/leading orbits or Distant Retrograde Orbits), where thrust requirement to maintain formation is primarily in a single direction (either sunward or anti-sunward), can be quite minuscule (a few m/s/year), and preferably met by constant-thrust engines such as solar electric propulsion or even by solar sailing via simple extendable and/or orientable flaps or rudders.
Geometry to Build Models, Models to Visualize Geometry
Authors: Cumino Caterina , Pavignano Martino , Spreafico Maria L. , Zich Ursula 
Published: September 2020

AbstractIn the seventeenth century, Guarino Guarini, mathematician and architect, affirmed that architecture, a discipline that primarily deals with measures, relies on geometry: therefore, the architect needs to know at least its basic principles. On behalf of Guarini’s words, we designed a set of interdisciplinary teaching experiences, between mathematics (via a calculus course) and drawing (via our Architectural Drawing and Survey Laboratory courses) that we proposed to first-year under graduate students studying for an Architecture degree. The tasks concern mathematical and representational issues about vaulted roofing systems and are based on the use of physical models in conjunction with digital tools, in order to make the cognitive geometric process more effective, thus following a consolidated tradition of both disciplines.
Prognosis in colorectal cancer beyond TNM
Authors: Neves Ana Lídia Ferreira , Barbosa Laura Elisabete Ribeiro , Teixeira João Paulo Meireles de Araújo 
Published: September 2020

Abstract
Introduction Colorectal cancer is one of the neoplasms with the greatest social impact. Given the great molecular heterogeneity and diversity of pathophysiological mechanisms, it is difficult to define prognostic factors that could guide therapy.
Objectives To identify the molecular prognostic factors that may be of interest in clinical practice and to synthesize the existing evidence.
Material and methods The search for the articles was carried out using the PubMed platform and the keywords “sporadic colorectal cancer and prognosis”, for articles published between 2014 and 2019. We selected all articles published on studies in humans and written in English or Portuguese. Of the 215 articles found, 35 articles were selected to perform this review.
Results Current evidence supports the use of four molecular markers in clinical practice − KRAS, NRAS and BRAF (EGFR signalling pathway) and the mismatch repair status.
Conclusion The use of molecular biomarkers in clinical practice to define prognosis is still little supported by the existent evidence. The studies are slightly contradictory, so new projects and international collaborations must be carried out in this area to obtain more robust evidence.
A Pragmatic Approach to the Perioperative Management of Parkinson’s Disease
Authors: Lenka Abhishek , Mittal Shivam Om , Lamotte Guillaume , Pagan Fernando Luis 
Published: September 2020

ABSTRACT:Patients with Parkinson’s disease (PD) may undergo several elective and emergency surgeries. Motor fluctuations, the presence of a wide range of non-motor symptoms (NMS), and the use of several medications, often not limited to dopaminergic agents, make the perioperative management of PD challenging. However, the literature on perioperative management of PD is sparse. In this descriptive review article, we comprehensively discuss the issues in the pre-, intra-, and postoperative phases which may negatively affect the PD patients and discuss the approach to their prevention and management. The major preoperative challenges include accurate medication reconciliation and administration of the dopaminergic medications during thenil per os(NPO) state. While the former can be addressed with staff education and PD-specific admission protocols, knowledge of non-oral formulations of dopaminergic agents (apomorphine, inhalational levodopa, and rotigotine transdermal patch) is the key to the management of the Parkinsonian symptoms in NPO state. Deep brain stimulation (DBS) devices should be turned off to avert potential electromagnetic interference with surgical appliances. Choosing the appropriate anesthesia and avoiding and managing respiratory issues and dysautonomia are the major intraoperative challenges. Timely reinitiation of dopaminergic medications, adequate management of pain, nausea, and vomiting, and prevention of postoperative infections and delirium are the postoperative challenges. Overall, a multidisciplinary approach is pivotal to prevent and manage the perioperative complications in PD. Administration of anti-Parkinson medications during NPO state, prevention of anesthesia-related complications, and timely rehabilitation remain the key to healthy surgical outcomes.
Punishment and Retribution Within the Bail Process: An Analysis of the Public Confidence in the Administration of Justice Ground for Pre-Trial Detention
Authors: Manikis Marie , De Santi Jess 
Published: September 2020

AbstractThis paper argues that lower courts have used their discretionary powers provided within legislation and St-Cloud to infuse a predominantly retributive interpretation into the public confidence in the administration of justice ground of pre-trial detention. This is illustrated notably by their choice of and weight afforded to the various aggravating and mitigating factors, the circumstances that relate to the commission of the offence, as well as their analysis of the length of imprisonment. This transfer of sentencing rationales, and to a greater extent, retributivism, into the third ground of pre-trial detention is used, in part, to justify pre-trial detention and can partially explain the rates of pre-trial detention. Finally, the underlying sentencing logic within the bail process can be understood within a sociological perspective, which examines the wider social functions of institutions and suggests that the bail process is an extension of punishment that serves to reinstate social order and public confidence.
Atopidae (Trilobita) in the upper Marianian (Cambrian Series 2, Stage 4) of Iberia
Authors: Collantes Luis , Mayoral Eduardo , Liñán Eladio , Gozalo Rodolfo 
Published: September 2020

AbstractNew atopid trilobites are described from the early Cambrian Cumbres beds and Herrerías shale of northern Huelva Province (Andalusia, Spain) and are dated as middle–late Marianian (Cambrian Series 2, Stage 4). New specimens ofAtops calanusRichter and Richter, 1941 are described and the Laurentian speciesPseudatops reticulatus(Walcott, 1890b) is recognized for the first time in the Mediterranean subprovince. The associated trilobite assemblage studied herein suggests an age close to the base of Cambrian Stage 4.
Walk or Run to Quit: a 3-year evaluation of a physical activity-based smoking cessation intervention
Authors: Priebe Carly S. , Wunderlich Kelly , Atkinson John , Faulkner Guy 
Published: September 2020

AbstractIntroductionWalk or Run to Quit was a national program targeting smoking cessation through group-based running clinics. Increasing physical activity may facilitate smoking cessation as well as lead to additional health benefits beyond cessation.AimTo evaluate the impact of Walk or Run to Quit over 3 years.MethodsAdult male and female participants (N = 745) looking to quit smoking took part in 156 running-based cessation clinics in 79 locations across Canada. Using a pre-post design, participants completed questionnaires assessing physical activity, running frequency and smoking at the beginning and end of the 10-week program and at 6-months follow-up. Carbon monoxide testing pre- and post- provided an objective indicator of smoking status and coach logs assessed implementation.Results55.0% of program completers achieved 7-day point prevalence (intent-to-treat = 22.1%) and carbon monoxide significantly decreased from weeks 1 to 10 (P < 0.001). There was an increase in physical activity and running from baseline to end-of-program (P's<0.001). At 6-month follow-up, 28.9% of participants contacted self-reported prolonged 6-month abstinence (intent-to-treat = 11.4%) and 35.6% were still running regularly.ConclusionsAlthough attrition was a concern, Walk or Run to Quit demonstrated potential as a scalable behaviour change intervention that targets both cessation and physical activity.