bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation Between the Extension of the Maxillary Sinus Floor and Malocclusion in Adolescent Patients Using a Cone-Beam Computed Tomography
Authors: xu min , zhang xiaoxiao , he jiacai , guo xinxing , sang yuanyuan , zhang zheng , wang yuanyin , xu wenhua , xu jianguang 
Published: May 2020

Abstract
Background: The correlation between extension of the maxillary sinus floor and vertical facial skeletal patterns is important for designing orthodontic treatment plans. We correlated the extension of the maxillary sinus (MS) floor with different facial skeletal malocclusion in adolescent patients aged 10-19 years old using a cone-beam computed tomography. Methods: The relationship between the root tips of upper posterior teeth and the sinus floor was typed and scored (0-4) using cone-beam computed tomography (CBCT) images. Scores of each tooth and each patient were formulated.The cephalometric radiographs were analyzed with Dolphin software to diagnose patients' facial skeletal types into three groups according to Frankfort mandibular plane angle (FMA) as high-angle, average-angle and low-angle groups and ANB angle as Class I, Class II and Class III groups separately. The influences caused by age, sex, and facial skeletal malocclusion on the tooth and patient score were analyzed. Results: In high-angle group, the first molar (FM) score was significantly higher than that in the average-angle and low-angle groups (P = 0.018). Age has a positive effect on the patient score and some of the tooth scores, such as the second premolar (SPM) score, FM score, and the second molar (SM) score, and in the skeletal facial malocclusion. With increasing age, SM score increased along with the Frankfort mandibular plane angle (FMA). No significant difference was found in the distribution of patient and tooth scores by ANB angles. Conclusion: The relationship between the maxillary posterior roots and the sinus floor is correlated with facial skeletal malocclusion in 10- to 19-year-old adolescents. More first molar root tips were inside the sinus in the high-angle group compared with the average-angle and low-angle skeletal patterns. With advancing age, more second molar root tips were more close to contact the sinus floor in the high-angle group. Consideration of the root-sinus position in the posterior maxillary area before establishing an orthodontic treatment plan is recommended.
A biomechanics study about ligaments injury in anterior posterior compression type Ⅱ pelvic injury
Authors: kong jianzhong , Chu Yupeng , Zhou Chengwei , Sun shuaibo , Bao guodong , Xu yu , Guo xiaoshan , Shui xiaolong 
Published: May 2020

Abstract
Background
Anterior posterior compression(APC)type II pelvis fracture is considered to be a typical one caused by the destruction of pelvic ligaments, while the mechanism of ligaments injury is still controversial. This study aims to explore ligaments injury in APC type II pelvic injury.
Method:
Fourteen human cadaveric pelvis samples with sacrospinous ligament (SPL), sacrotuberous ligament (SBL), anterior sacroiliac ligament (ASL) and partial bone retaining unilaterally were made for this study. They were divided into hemipelvis restricted group and unrestricted group randomly. Record the separation distance of pubic symphysis and anterior sacroiliac joint, external rotation angle and force when the ASL ruptured. Continuing external rotation violence, observing bone and pelvic ligaments change.
Result
When ASL failed, there were no significant differences in mean separation distance of pubic symphysis (28.6 ± 8.4 mm to 23.6 ± 8.2 mm,P = 0.11) and anterior sacroiliac joint (11.4 ± 3.8 mm to 9.7 ± 3.9 mm ,P = 0.30) between restricted group and unrestricted group, but external rotation angle(33.9 ± 5.5° to 48.9 ± 5.2°,P < 0.01) and force(553.9 ± 82.6 N to 756.6 ± 41.4 N,P < 0.01) were not. In restricted group, both of SAL and SPL injury occurred, which was different in unrestricted group. Besides, separation distance of pubic symphysis between two groups ranged from 14 mm to 40 mm. With external rotation violence continuing, SPL ruptured firstly, then SBL ruptured and the interosseous sacroiliac ligament was damaged while posterior ligament was not; in another group, interosseous sacroiliac ligament, posterior sacroiliac ligaments were damaged while SAC and SPL were not. When all of ASL, SBL, SPL failed, mean separation distance of pubic symphysis and anterior sacroiliac joint between two groups increased significantly (from 28.6 ± 8.4 to 42.0 ± 7.6 mm, 11.4 ± 3.8 to 16.7 ± 4.2 mm respectively, all P < 0.05).
Conclusion
First, pelvic external rotation injury can divide into hemipelvis is restricted and unrestricted, which result into different outcomes; When ASL ruptures, the unrestricted group needs more external rotation angle and force, without SBL or SPL injury. But in restricted group, both of two ligaments are injured. Second, when ASL fails, pubic symphysis displacement has a high fluctuation. Third, ASL rupture does not mean SBL and SPL are injured inevitably.
Treatment and monitoring remain the purview of the doctor: Health literacy of people struggling with insufficiently controlled type 2 diabetes. A longitudinal qualitative study
Authors: Debussche Xavier , Balcou-Debussche Maryvette , Ballet Delphine , Caroupin-Soupoutevin Jessica 
Published: May 2020

Abstract
Background

Assessing complex health literacy needs is a key element to improve management of diabetes in vulnerable people. This study aimed to analyse health literacy and practices in insufficiently controlled type 2 diabetes.
Methods

Data are issued from the qualitative ERMIES-ethnosocio study nested in the ERMIES randomized controlled trial testing a 2 years structured care in type 2 diabetes. A total of 42 participants were seen at the beginning and after the completion of the trial. Interviews explored experiences and views on daily management of diabetes. Health literacy was assessed via the multidimensional Health Literacy Questionnaire.
Results

Eight themes grouped in 3 main poles could be individualized: health knowledge, disease management, expertise and social support. Participants exhibited a primarily one-way relationship to treatment and monitoring, leaving the health care providers (HCP) the initiatives. In contrast, relation to food practices and exercise were more interactive. After 2 years participants tended to engage a more interactive relation to treatment. Having sufficient, appraising, and feeling able to find good health information were at stake while social support for health and relation to HCP and services were important determinants for managing health.
Conclusion

This longitudinal qualitative study shows the inter-individual et intra-individual variations of health literacy related to disease management, with the importance of the relation type to HCP, as well as social context with complex and evolving interactions. Decision-making as a shared social task beside the resources for engaging with health services are key considerations in the co-design of relevant interventions in type 2 diabetes.
Barriers and facilitators of completing the steps in the PMTCT cascade at Midwife Obstetric Units in Gauteng - Healthcare Provider and Patient's views
Authors: Mongwenyana Constance , Jinga Nelly , Mohomi Given , Buthelezi Sindisiwe , Nkopane Nancy , Moolla Aneesa , Onoya Dorina 
Published: May 2020

Abstract
Background: The implementation of Prevention of Mother to Child Transmission (PMTCT) programmes at midwifes obstetric units (MOU) involves the confirmation of HIV diagnosis during labour, early infant HIV diagnosis (EID), initiation/continuation of antiretroviral therapy (ART) for mother and baby as appropriate and counselling for postpartum care. Objectives: The aim of this study was to explore the barriers and facilitators to completing the steps in the PMTCT cascade at MOUs as defined by healthcare providers and recently postpartum women. Methods: We conducted 10 in-depth interviews with healthcare providers, and 24 HIV positive and HIV negative women at the four MOUs and Primary Healthcare Centres (PHC’s) in Gauteng South Africa (SA). Results: The implementation of PMTCT at MOU is impeded by maternal denial of HIV status (both new diagnoses and ANC diagnoses). Challenges with acceptance and disclosure of HIV status were thought to compromise patient commitment to EID tests and postpartum adherence to infant ART. Newly diagnosed (during labour) patients have limited time to process new HIV diagnosis and clinics have limited nurse/counsellor capacity for further one on one counselling. Additional challenges include communication challenges with foreign women and turnaround time for birth HIV tests. Results are often not available at postnatal visit and unclear processes for referral to Primary Healthcare Centre (PHC) for postpartum care increase risk of postpartum loss to follow up. Conclusion: We need to strengthen MOU capacity to prepare women for postpartum PMTCT requirements and facilitate access to EID results. Patient referral processes, including communication of infant HIV test results to the referral PHC, needs improvement.
Hypertension prevalence, awareness, treatment, and control and predicted 10-year CVD risk: a cross-sectional study of Seven Communities in East and West Africa (SevenCEWA)
Authors: Okello Samson , Muhihi Alfa , Mohamed Shukri F , Ameh Soter , Ochimana Caleb , Oluwasanu Abayomi Olabayo , Bolarinwa Oladimeji Akeem , Sewankambo Nelson , Danaei Goodarz 
Published: May 2020

Abstract
Background
Few studies have characterized epidemiology and management of hypertension across several communities with comparable methodology in sub-Saharan Africa. We assessed prevalence, awareness, treatment, and control of hypertension and predicted 10-year cardiovascular disease risk across seven sites in East and West Africa.
Methods
Between June and August 2018, we conducted household surveys in 7 communities in Kenya, Nigeria, Tanzania, and Uganda and collected data on socio-demographics, health insurance, and healthcare utilization. We measured blood pressure using a standardized protocol and digital monitors. We estimated 10-year cardiovascular disease (CVD) risk using a country-specific risk score and fit hierarchical models to identify determinants of hypertension prevalence, awareness and treatment.
Results
We analyzed data of 3549 participants with a mean age of 39·7 years (SD 15·4), 60·5% of whom were women, 9·6% had ever smoked, and 32·7% were overweight/obese. A quarter (901, 25·1% (95% Confidence Interval 23·7%, 26·6%)) of participants had hypertension, half of whom (515, 57·6%) were diagnosed. Among diagnosed, 50·5% (260) were taking medication, and among those taking medication 47·3%(123) were controlled. After adjusting for other determinants, older age was associated with increased hypertension prevalence, awareness, and treatment whereas primary education was associated with lower hypertension prevalence. Health insurance was associated with lower hypertension prevalence and higher chances of treatment. Median predicted 10-yr CVD risk across sites was 4·9% Interquartile range, IQR (2·4%, 10·3%) and 13·2% had risk of 20% or greater while 7·1% had risk of > 30%.
Conclusion
In seven communities in east and west Africa, a quarter of adults had hypertension, about 40% were unaware, half of those aware were treated and half of those treated were controlled blood pressure. Access to health insurance is needed to improve awareness, treatment, and control of hypertension in sub-Saharan Africa.
Prevalence of Non-Communicable Diseases and its Risk Factors among Ijegun-Isheri Osun Residents in Lagos State, Nigeria: A Community Based Cross-Sectional Study
Authors: Israel Idris Oluwaseyidayo , Oguntade Ayodipupo Sikiru , Mensah Ekow Adom , Kitamura Noriko 
Published: May 2020

Abstract
Background
The rapid epidemiologic transition of diseases has adverse implications for low-and middle-income countries (LMICs) due to their limited healthcare, weaker health systems and the westernization of lifestyle. There is the need to evaluate the enormity or otherwise of the NCD burden and address it. However, there is a paucity of literature on the burden of NCDs in Nigeria. We therefore conducted this survey to determine the prevalence of NCDs and its risk factors among the Ijegun- Isheri Osun community residents of Lagos, Nigeria.
Methods
A community-based cross-sectional survey design was applied with 215 participants selected consecutively during a population preventive health campaign. Prevalence of hypertension, diabetes and dyslipidaemia were calculated, with further exploration on associations between these variables done. Multivariable logistic regression was used to estimate the risk factors of the three NCDs (hypertension, diabetes and dyslipidaemia).
Results
The prevalence of hypertension was 35.3% (95%CI 29.0-42.1), diabetes 4.6% (95%CI 2.2–8.4) and dyslipidemia 47.1% (95%CI 41.1–54.8). Three major risk factors evaluated showed prevalence of smoking to be 41.3% (95%CI 34.2–48.6), alcohol consumption 72.5% (95% CI 65.5–78.7), and physical activity 52.9 (95%CI 45.5–60.2). The independent significant risk factors of hypertension were age ≥ 60 years (aOR 4.56 95%CI: 1.72–12.09) and dyslipidaemia (aOR 5.01 95%CI: 2.26–11.13). Age age ≥ 60 years (aOR 8.83 95%CI: 1.88–41.55) was an independent risk factor of diabetes. Age age ≥ 60 years aOR 29.32 95%CI: 4.78-179.84), being employed (aOR 11.12 95%CI: 3.10-39.92), smoking (aOR 2.34 95%CI: 1.03–5.33) and physical activity (aOR 0.34 95%CI: 0.15–0.76) were independent risk factors of having dyslipidaemia.
Conclusions
The results suggest that prevalence of hypertension, diabetes and dyslipidaemia together with their associated risk factors are high, highlighting the need for further implementation research and policy directions to tackle the NDC burden in the research community, Nigeria, sub-Saharan Africa and the world at large. These strategies must be community specific, prioritizing the various risk factors and addressing them accordingly.
Ethnomedicine and Traditional Health Care System of a Particular Vulnerable Tribal Group in India: Application of Plant Extracts
Authors: Sahoo Amiya Kumar , Behera Hari Charan , Behura Ajit Kumar 
Published: May 2020

Abstract
Background

The exploration on association of between human and nature has made conceivable to comprehend the undercurrent lifestyle of the communities and the ecosystem in which they inhabit together. Over the last decade there has been a rise of ethnomedicinal studies, still small is known about use of ethnomedicine in traditional health care system of the Juang, which is one of the 75 particularly vulnerable tribal groups (PVTGs) in India. Traditional system is unique and undeniably an important cultural ingredient. The aim of the present study was to document the ethnomedicinal practices of the Juang, who live in forest fringes and hill tracks and derive their livelihood from forest-based resources. They used varieties of plant extracts, traditional knowledge and belief system for treatment as well as prevention of from various disease and ailments.
Methods

Besides questionnaire as a tool for data collection, Interview, observation (both participant and non-participant observation) and focus group discussion (FGD) were used. Field surveys were carried out in three phases. The informants were selected through the snowball sampling technique. Twelve males and two females key informants were interviewed. The study was exploratory and qualitative in nature.
Results

It was found that 38 medicinal plant species belong to 26 families as having ethnomedicinal uses in the traditional health care practice among the Juang community. Comparatively leaf part (36%) frequently utilized followed by root (21%), seed (7%), bark (7%), fruit (6%), rootstock (4%) and tender twig (3%) for medicinal purposes.
Conclusions

Our study can be concluded that the Juang people are rich in indigenous knowledge and have provided novel information on the use of medicinal plants to cure, protect and prevent from various diseases and ailments, that are scientific in nature. The novel information has been generated in the present study which will through a light in the direction of modern medical science for the sustainability of human society and recognize the indigenous knowledge as well. We suggested that indigenous knowledge need to be documented and integrated with scientific knowledge to develop new health care management programme.
Comparison of Volume Changes in Different Environmental Conditions After Retrofilling Using Three Calcium Silicate Cements
Authors: kwon so yeon , seo minseock 
Published: May 2020

Abstract
Background The present study aimed to compare the marginal sealing ability of three calcium silicate cements after retrofilling at different pH levels via micro-computed tomography (CT) scan.Methods Forty-two extracted human single-rooted teeth were randomly assigned to three groups according to the retrofilling materials used (Biodentine, Endocem MTA, and ProRoot MTA). Each group was divided into two subgroups according to the setting condition. The teeth in one group were immersed in normal saline for 5 days at room temperature, and the teeth in the other group were immersed in butyric acid (pH = 5.4) for 5 days at room temperature. To investigate marginal sealing ability, the volume ratios of the retrofilling material were calculated via micro-CT imaging.Results The volume ratios of the Biodentine and Endocem MTA groups were significantly different between the two setting environment, and these groups had significantly lower filled volume ratio (Vf, %) in the acidic environment than in the saline environment (pH = 5.4). Meanwhile, the volume ratio of the ProRoot MTA group did not significantly differ between the two setting environments. All materials under the acidic setting condition had relative radiolucency in the area in contact with the acidic solution.Conclusions The Vf ratio of the Biodentine and Endocem MTA cements was significantly lower in the acidic environment than in the saline environment. Meanwhile, no statistically significant difference was observed in the Vf ratio of ProRoot MTA between the two setting environments.
The Role of Fever Clinic During the COVID-19 Pandemic: A case study of 1034 febrile patients
Authors: Tang Li , He Yanxia , Bai Fangjing , Luo Bin 
Published: May 2020

Abstract
Background

Since winter of 2019, when coronavirus disease 2019 (Covid-19) emerged in China and rapidly spread throughout the entire world, many fever clinics were rearranged and enlarged to triage febrile patients in China.
Methods

This study included fever clinic visits of Sichuan Provincial Peoples’ Hospital to summarize the characteristics of these febrile patients retrospectively.
Results

From 24th January to 31th March, 1034 fever clinic visits with 530 male and 504 female, were triaged, treated and recorded. About 64.9% of them were checked with body temperature higher than 37.3℃. Cough (25.0%) and sore throat (19.2%) were the most common symptoms in addition to fever. Chest CT scan was ordered for 900 patients, and 172 cases (16.6%) were found ground grass opacity, 134 (13.0%) found local patchy shadowing, and 26 (2.5%) found bilateral patchy shadowing. At last 851 patients (82.3%) were excluded for COVID-19 or other severe diseases. Eighty patients (7.7%) were admitted to hospitalization for other conditions. One hundred and three (9.9%) patients were suspected or confirmed of COVID-19 at fever clinic, and then admitted to isolation ward.
Conclusions

The result of this study again verified the extraordinary role of fever clinics in pandemics. When confronted with a mass of unknown febrile patients, a well organized fever clinic may avoid the frustration of all medical staffs.
From SARS to COVID-19: A Bibliometric study on Emerging Infectious Diseases with Natural Language Processing technologies
Authors: Hu Yinjun , Chen Mengmeng , Wang Qian , Zhu Yue , Wang Bei , Li Sufei , Xu Yongbin , Zhang Yaohua , Liu Meihua , Wang Ying , Hu Yihe , Liu Jinyuan 
Published: May 2020

Abstract
[Background] On January 7, 2020, the novel coronavirus named "COVID-19" aroused worldwide concern was identified by Chinese scientists. Many related research works were developed for the emerging, rapidly evolving situation of this epidemic. This study aimed to analyze the research literatures on SARS, MERS and COVID-19 to retrieve important information for virologists, epidemiologist and policy decision makers. [Methods] In this study, we collected data from multi data sources and compared bibliometrics indices among COVID-19, Severe Acute Respiratory Syndrome (SARS), and Middle East Respiratory Syndrome (MERS) up to March 25, 2020. In purpose to extract data in corresponding quantity and scale, the volume of search results will be balance with the limitation of publication years. For further analysis, we extracted 1,480 documents from 1,671 candidates with Natural Language Processing technologies. [Results] In total, 13,945 research literatures of 7 datasets were selected for analysis. Unlike other topics, research passion on epidemic may reach its peak at the first year the outbreak happens. The document type distribution of SARS, MERS and COVID-19 are nearly the same (less than 6 point difference for each type), however, there were notable growth in the research qualities during these three epidemics (3.68, 6.63 and 11.35 for Field-Weighted Citation Impact scores). Asian countries has less international collaboration (less than 35.1\%) than the Occident (more than 49.5\%), which should be noticed as same as research itself. [Conclusions] We found that research passion on epidemics may always reach its peak at the first year after outburst, however, the peak of research on MERS appeared at the third year because of its outburst of reproduction in 2015. For the research quality, although we did better in research qualities than before especially on COVID-19, research on epidemics not started from our own country should not be looked down. Another important effective strategy for enhancing epidemic prevention for China and other Asian countries is to continue strengthening international collaboration.
Vaccine Design against Coronavirus Spike (S) Glycoprotein in Chicken: Immunoinformatic and Computational Approaches
Authors: Ali Sumaia Awad Elkariem , Awadelkareem Eman Ali 
Published: May 2020

Abstract
Background: Infectious bronchitis (IB) is a highly contagious respiratory disease in chickens and produces economic loss within the poultry industry. It is caused by a single stranded RNA virus belonging to Cronaviridae family. Methods: The present study used various tools in Immune Epitope Database (IEDB) to predict conserved B and T cell epitopes against IBV spike (S) protein that may perform a significant role in provoking the resistance response to IBV infection. Results: In B cell prediction methods, three epitopes (1139KKSSYY1144, 1140KSSYYT1145, 1141SSYYT1145) were selected as surface, linear and antigenic epitopes. Many MHCI and MHCII epitopes were predicted for IBV S protein. Among them 982YYITARDMY990 and 983YITARDMYM991 epitopes displayed high antigenicity, no allergenicity and no toxicity as well as great linkage with MHCI and MHCII alleles. Moreover, docking analysis of MHCI epitope produced strong binding affinity with BF2 alleles. Conclusion: Five conserved epitopes were expected from spike glycoprotein of IBV as the best B cell and T cell epitopes due to high antigenicity, no allergenicity and no toxicity. In addition, MHC epitopes showed great linkage with MHC alleles as well as strong interaction with BF2 alleles. These epitopes should be designed and incorporated and then tested as multi-epitope vaccine against IBV.