bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic Lateralization in the Hypothalamus of Male Rats Related to Reproductive and Satiety States
Authors: Kiss David S. , Toth Istvan , Jocsak Gergely , Bartha Tibor , Frenyo Laszlo V. , Barany Zoltan , Horvath Tamas L. , Zsarnovszky Attila 
Published: February 2020

AbstractThe hypothalamus is the main regulatory center of many homeostatic processes, such as reproduction, food intake, and sleep-wake behavior. Recent findings show that there is a strongly interdependent side-linked localization of hypothalamic functions between the left and right hemispheres. The goal of the present study was to trace functional asymmetry of the hypothalamus related to the regulation of food intake and reproduction, in male rodents. Subjects were examined through measurements of mitochondrial metabolism ex vivo. Impact of gonadectomy and scheduled feeding was tested on the modulation of hypothalamic metabolic asymmetry. Results show that in male rats, functional lateralization of the hypothalamus can be attributed to the satiety state rather than to reproductive control. Fasting caused left-sided metabolic dominance, while satiety was linked to the right hemisphere; trends and direction in sided dominance gradually followed the changes in satiety state. Our findings revealed satiety state-dependent metabolic differences between the two hypothalamic hemispheres. It is therefore concluded that, at least in male rats, the hypothalamic hemispheres control the satiety state-related functions in an asymmetric manner.
Does Lent affect rates of deliberate self-harm?
Authors: Moloney N. , Glynn K. , Harding E. , Murphy V. , Gulati G. 
Published: February 2020

BackgroundResearch has shown that religious affiliation has a protective effect against deliberate self-harm. This is particularly pronounced in periods of increased religious significance, such as periods of worship, celebration, and fasting. However, no data exist as to whether this effect is present during the Christian period of Lent. Our hypothesis was that Lent would lead to decreased presentations of self-harm emergency department (ED) in a predominantly Catholic area of Ireland.MethodsFollowing ethical approval, we retrospectively analysed data on presentations to the ED of University Hospital Limerick during the period of Lent and the 40 days immediately preceding it. Frequency data were compared using Pearson’s chi-squared tests in SPSS.ResultsThere was no significant difference in the overall number of people presenting to the ED with self-harm during Lent compared to the 40 days preceding it (χ2 = 0.75, df = 1, p > 0.05), and there was no difference in methods of self-harm used. However, there was a significant increase in attendances with self-harm during Lent in the over 50’s age group (χ2 = 7.76, df = 1, p = 0.005).ConclusionsBased on our study, Lent is not a protective factor for deliberate self-harm and was associated with increased presentations in the over 50’s age group. Further large-scale studies are warranted to investigate this finding as it has implications for prevention and management of deliberate self-harm.
Nationalism and Communism as Foes and Friends
Authors: Zhou Luyang 
Published: February 2020

AbstractSociologists have noted that the ideological inclusiveness of nationalism varies. By comparing the Bolshevik and Chinese communist revolutionary elites, this article explains that such variation depends on the social strength of nationalism. A strong nationalism is (a) undergirded by a widely diffused national culture that can socialize most radical elites into the nation; (b) kept institutionally open to broad social strata so that lower classes can form a nationalist identity through participation; and (c) universally believed to be a geopolitically feasible anti-colonial revolution so that radical elites can think of engagement as worthwhile and necessary. Using a comparative biographical method probing both nationalists and communists, this article demonstrates that nationalism in Tsarist Russia was far weaker than in post-imperial China. In the former, the nationalist movement excluded communists while, in the latter, communists were incorporated. Therefore, the two communist parties had different understandings of Marxism.
Robust Motion Planning in Dynamic Environments Based on Sampled-Data Hamilton–Jacobi Reachability
Authors: Kleff Sébastien , Li Ning 
Published: February 2020

SUMMARYWe propose a novel formal approach to robust motion planning (MP) in dynamic environments based on reachability analysis. While traditional MP methods usually fail to provide formal robust safety and performance guarantees, our approach provably ensures safe task achievement in time-varying and adversarial environments under parametric uncertainty. We leverage recent results on Hamilton–Jacobi (HJ) reachability and differential games in order to compute offline guaranteed motion plans that are compatible with the sampled-data (SD) paradigm. Also, we synthesize online provably robust safety-preserving and target-reaching feedback controls. Unlike earlier applications of reachability analysis to MP, our methodology handles arbitrary time-varying constraints, adversarial agents such as pursuing obstacles or evading targets, and takes into account the robot’s configuration. Furthermore, we use HJ projections in order to reduce significantly the computational burden without trading off safety guarantees. The validity of this approach is demonstrated through the case study of a robot arm subject to measurement errors, which is tasked with safely reaching a goal in a known time-varying workspace while avoiding capture by an unpredictable pursuer. Finally, the performance of the approach and research perspectives are discussed.
Performance and modification of EGCRISC among hepatitis C virus high-risk groups
Authors: El-Ghitany E. M. , Alkassabany Y. M. , Farghaly A. G. 
Published: February 2020

Abstract
We have previously shown that the Egyptian Hepatitis C Virus Risk Score (EGCRISC), an Egyptian hepatitis C virus (HCV) risk-based screening tool, to be valid and cost-effective. Certain behaviours, occupations and diseases have been shown to be associated with an increased risk of exposure to HCV infection and constitute a major population reservoir of HCV infection. This study investigated the efficacy of EGCRISC in selected high-risk groups by testing 863 participants from four groups: slaughterhouse workers, illicit drug users (IDUs), female sex workers and human immune deficiency virus (HIV) patients. Data for this study were collected on EGCRISC and another pre-designed risk factor questionnaire. Sera were tested for HCV antibodies by ELISA. EGCRISC, at lower cut-off points, showed significantly good performance (P < 0.05) in all four groups except for females <45 years, but was reliable in detecting HCV cases (sensitivity: 84.21% and negative predictive value: 94.5%). Specific scores for IDUs and HIV patients were developed that showed high accuracy (P < 0.001). A modified EGCRISC for high-risk groups (EGCRISC-HRGs) was shown to be a valid tool that is recommended for use in high-risk populations if no other specific screening tool is available or universal screening is applied. EGCRISC for IDUs (EGCRISC-IDUs) and EGCRISC for HIV patients (EGCRISC-HIV) are useful tools for preselecting potentially HCV-infected cases for further testing in settings where serological analysis is not readily available or accessible.
Co-circulation of influenza A(H1N1), A(H3N2), B(Yamagata) and B(Victoria) during the 2017−2018 influenza season in Zhejiang Province, China
Authors: Mao Haiyan , Sun Yi , Chen Yin , Lou Xiuyu , Yu Zhao , Wang Xinying , Ding Zheyuan , Cheng Wei , Zhang Dan , Zhang Yanjun , Jiang Jianmin 
Published: February 2020

Abstract
Influenza is a major human respiratory pathogen. Due to the high levels of influenza-like illness (ILI) in Zhejiang, China, the control and prevention of influenza was challenging during the 2017–2018 season. To identify the clinical spectrum of illness related to influenza and characterise the circulating influenza virus strains during this period, the characteristics of ILI were studied. Viral sequencing and phylogenetic analyses were conducted to investigate the virus types, substitutions at the amino acid level and phylogenetic relationships between sequences. This study has shown that the 2017/18 influenza season was characterised by the co-circulation of influenza A (H1N1) pdm09, A (H3N2) and B viruses (both Yamagata and Victoria lineage). From week 36 of 2017 to week 12 of 2018, ILI cases accounted for 5.58% of the total number of outpatient and emergency patient visits at the surveillance sites. Several amino acid substitutions were detected. Vaccination mismatch may be a potential reason for the high percentage of ILI. Furthermore, it is likely that multiple viral introductions played a role in the endemic co-circulation of influenza in Zhejiang, China. More detailed information regarding the molecular epidemiology of influenza should be included in long-term influenza surveillance.
Trade and National Security: Rising Risks for the WTO
Authors: Prazeres Tatiana Lacerda 
Published: February 2020

AbstractThe WTO is exposed to significant political risks deriving from both the abusive employment of the national security argument, as well as the use of the WTO dispute settlement system to address this problem. This article explores the implications of the first WTO panel decision, adopted in April 2019, in which the argument of ‘essential security interests’ was employed to justify trade restrictions. Article XXI of the GATT 1994 now tends to be invoked in other ongoing disputes, notably by the United States in the dispute settlement cases involving its barriers to steel and aluminum. The article argues that pathways other than WTO litigation should be explored to deal with trade barriers adopted under the argument of national security and, despite the absence of simple solutions, it considers some possible alternatives.
The First WTO's Ruling on National Security Exception: Balancing Interests or Opening Pandora's Box?
Authors: Boklan Daria , Bahri Amrita 
Published: February 2020

AbstractFor a multilateral system to be sustainable, it is important to have several escape clauses which can allow countries to protect their national security concerns. However, when these escape windows are too wide or ambiguous, defining their ambit and scope becomes challenging yet crucial to ensure that they are not open to misuse. The recent Panel Ruling inRussia – Measures Concerning Traffic in Transitis the very first attempt by the WTO to clarify the scope and ambit of National Security Exception. In this paper, we argue that the Panel has employed a combination of an objective and a subjective approach to interpret this exception. This hybrid approach to interpret GATT Article XXI (b) provides a systemic balance between the sovereign rights of the members to invoke the security exception and their right to free and open trade. But has this Ruling opened Pandora's box? In this paper, we address this issue by providing an in-depth analysis of the Panel's decision.
Multiple herbicide–resistant Lolium spp. is prevalent in wheat production in Texas Blacklands
Authors: Singh Vijay , Maity Aniruddha , Abugho Seth , Swart James , Drake David , Bagavathiannan Muthukumar 
Published: February 2020

AbstractField surveys were conducted across the Blacklands region of Texas during 2016 and 2017 to document the distribution of herbicide-resistant Lolium spp. infesting winter wheat production fields in the region. A total of 68 populations (64 Italian ryegrass, four perennial ryegrass) were evaluated in a greenhouse for sensitivity to herbicides of three different modes of action: an acetolactate synthase (ALS) inhibitor (mesosulfuron-methyl), two acetyl-coenzyme-A carboxylase (ACCase) inhibitors (diclofop-methyl and pinoxaden), and a 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) inhibitor (glyphosate). Herbicides were applied at twice the label-recommended rates for mesosulfuron-methyl (29 g ai ha−1), diclofop-methyl (750 g ai ha−1), and pinoxaden (118 g ai ha−1); and at the recommended rate for glyphosate (868 g ae ha−1). The herbicide screenings were followed by dose-response assays of the most-resistant ryegrass population for each herbicide at eight rates (0.5, 1, 2, 4, 8, 16, 32, and 64×), compared with a susceptible population at six rates (0.0625, 0.125, 0.25, 0.5, 1, and 2×). The initial screening and dose-response experiments were conducted in a completely randomized design with three replications and two experimental runs. Survivors (<80% injury) were characterized as highly resistant (0% to 20% injury) or moderately resistant (21% to 79%). Results showed that 97%, 92%, 39%, and 3% of the Italian ryegrass populations had survivors to diclofop-methyl, mesosulfuron-methyl, pinoxaden, and glyphosate treatments, respectively. Of the four perennial ryegrass populations, three were resistant to diclofop-methyl and mesosulfuron-methyl, and one was resistant to pinoxaden as well. Perennial ryegrass populations did not exhibit any resistance to glyphosate. Dose-response assays revealed 37-, 196-, and 23-fold resistance in Italian ryegrass to mesosulfuron-methyl, diclofop-methyl, and pinoxaden, respectively, compared with a susceptible standard. One Italian ryegrass population exhibited three-way multiple resistance to ACCase-, ALS-, and EPSPS-inhibitors. The proliferation of multiple herbicide–resistant ryegrass is a challenge to sustainable wheat production in Texas Blacklands and warrants diversified management strategies.
Multi‐instrumental Observations of the Quasi‐16‐Day Variations From the Lower Thermosphere to the Topside Ionosphere in the Low‐Latitude Eastern Asian Sector During the 2017 Sudden Stratospheric Warming Event
Authors: Liu Jing , Zhang Donghe , Hao Yongqiang , Xiao Zuo 
Published: February 2020

AbstractVariations of the low‐latitude ionosphere in the eastern Asian sector during the 2017 sudden stratospheric warming (SSW) were studied with multi‐instrumental observations that correspond to different altitudes. Specifically, the variations of the topside ionosphere as high as over 830 km were investigated with data from the Swarm B satellite (~500 km), the Defense Meteorological Satellite Program F15 satellite (~830 km), and the Meteorological Operational satellite‐A (~830 km). The main results are as follows. (1) Simultaneous variations were detected in the ionospheric parameters from the E region to the topside ionosphere around the first peak warming of the 2017 SSW. (2) These variations exhibited similar quasi‐16‐day (Q16D; ~14.5‐day) periods, and these periods were most significant just before the first peak warming. (3) These simultaneous Q16D variations were not due to the solar extreme ultraviolet irradiance or geomagnetic activities but were probably driven from below, by planetary waves or semidiurnal lunar tides that enhanced during the SSW. (4) The Q16D variation of the topside ionospheric electron density at ~830 km was probably driven not only by the upward mapping electric field modulated in the E region dynamo but also by the electric field modulated in the F region dynamo.
Inversion of Time‐Lapse Seismic Reservoir Monitoring Data Using CycleGAN: A Deep Learning‐Based Approach for Estimating Dynamic Reservoir Property Changes
Authors: Zhong Zhi , Sun Alexander Y. , Wu Xinming 
Published: February 2020

AbstractCarbon capture and storage is being pursued globally as a geoengineering measure for reducing the emission of anthropogenic
into the atmosphere. Comprehensive monitoring, verification, and accounting programs must be established for demonstrating the safe storage of injected CO
. One of the most commonly deployed monitoring techniques is time‐lapse seismic reservoir monitoring (also known as 4‐D seismic), which involves comparing 3‐D seismic survey data taken at the same study site but over different times. Analyses of 4‐D seismic data volumes can help improve the quality of storage reservoir characterization, track the movement of injected CO
plume, and identify potential CO
spillover/leakage from the storage reservoirblue. However, the derivation of high‐resolution CO
saturation maps from 4‐D seismic data is a highly nonlinear and ill‐posed inverse problem, often requiring significant computational effort. In this research, we apply a physics‐based deep learning method to facilitate the solution of both the forward and inverse problems in seismic inversion while honoring physical constraints. A cycle generative adversarial neural network (CycleGAN) model is trained to learn the bidirectional functional mappings between the reservoir dynamic property changes and seismic attribute changes, such that both forward and inverse solutions can be obtained efficiently from the trained model. We show that our CycleGAN‐based approach not only improves the reliability of 4‐D seismic inversion but also expedites the quantitative interpretation. Our deep learning‐based workflow is generic and can be readily used for reservoir characterization and reservoir model updates involving the use of 4‐D seismic data.
Ice Nucleation by Marine Aerosols Over the North Atlantic Ocean in Late Spring
Authors: Wilbourn Elise K. , Thornton Daniel C. O. , Ott Catherine , Graff Jason , Quinn Patricia K. , Bates Timothy S. , Betha Raghu , Russell Lynn M. , Behrenfeld Michael J. , Brooks Sarah D. 
Published: February 2020

AbstractHere we report the ice nucleating temperatures of marine aerosols sampled in the subarctic Atlantic Ocean during a phytoplankton bloom. Ice nucleation measurements were conducted on primary aerosol samples and phytoplankton isolated from seawater samples. Primary marine aerosol samples produced by a specialized aerosol generator (the Sea Sweep) catalyzed droplet freezing at temperatures between −33.4 °C and − 24.5 °C, with a mean freezing temperature of −28.5 °C, which was significantly warmer than the homogeneous freezing temperature of pure water in the atmosphere (−36 °C). Following a storm‐induced deep mixing event, ice nucleation activity was enhanced by two metrics: (1) the fraction of aerosols acting as ice nucleating particles (INPs) and (2) the nucleating temperatures, which were the warmest observed throughout the project. Seawater samples were collected from the ocean's surface and phytoplankton groups, including Synechococcus, picoeukaryotes, and nanoeukaryotes, were isolated into sodium chloride sheath fluid solution using a cell‐sorting flow cytometer. Marine aerosol containing Synechococcus, picoeukaryotes, and nanoeukaryotes serves as INP at temperatures significantly warmer than the homogeneous freezing temperature of pure water in the atmosphere. Samples containing whole organisms in 30 g L−1 NaCl had freezing temperatures between −33.8 and − 31.1 °C. Dilution of samples to representative atmospheric aerosol salt concentrations (as low as 3.75 g L−1 NaCl) raised freezing temperatures to as high as −22.1 °C. It follows that marine aerosols containing phytoplankton may have widespread influence on marine ice nucleation events by facilitating ice nucleation.
Feedbacks Between Surface Deformation and Permafrost Degradation in Ice Wedge Polygons, Arctic Coastal Plain, Alaska
Authors: Abolt Charles J. , Young Michael H. , Atchley Adam L. , Harp Dylan R. , Coon Ethan T. 
Published: February 2020

AbstractIn the past three decades, an abrupt, pan‐Arctic acceleration of ice wedge melting has transformed tundra landscapes, spurring the formation of hummock‐like features known as high‐centered polygons (HCPs). This rapid geomorphic transition profoundly alters regional hydrology and influences surface emissions of CO2 and CH4. In Arctic Alaska, most recent instances of ice wedge degradation have arrested within 15–20 years of inception, stabilizing HCP microtopography. However, feedbacks between ground surface deformation and permafrost stability are incompletely understood, limiting our capacity to predict trajectories of landscape evolution in a still warmer future. Here, we use field data from a site near Prudhoe Bay, Alaska, to develop a modeling‐based framework for assessing the strength of positive (i.e., exacerbating) feedbacks on ice wedge degradation, focusing on the importance of heterogeneity in surface drainage and microtopographic conditions. Our simulations suggest that, when troughs are narrow, positive feedbacks on ice wedge melting (associated with thermokarst pool formation) are relatively weak. Positive feedbacks are markedly stronger beneath wide troughs, such as those that form above older, larger ice wedges. Seasonal thaw abruptly accelerates once a talik begins to form beneath wide and deep thermokarst pools. Once a talik initiates, winter severity and snowpack thickness increase in importance as predictors of thaw intensity in summer. Our results indicate that meter‐scale heterogeneity in polygonal microtopography potentially exerts strong, nonlinear controls on thermokarst trajectories. These findings are useful for predicting future thermokarst dynamics and for interpreting the results from coarser‐resolution land surface models operating at greater spatial and temporal scales.
Evolutionary conservation of within-family biodiversity patterns
Authors: Laiolo Paola , Pato Joaquina , Jiménez-Alfaro Borja , Obeso José Ramón 
Published: February 2020

AbstractThe tendency for species to retain their ancestral biological properties has been widely demonstrated, but the effect of phylogenetic constraints when progressing from species to ensemble-level properties requires further assessment. Here we test whether community-level patterns (environmental shifts in local species richness and turnover) are phylogenetically conserved, assessing whether their similarity across different families of lichens, insects, and birds is dictated by the relatedness of these families. We show a significant phylogenetic signal in the shape of the species richness-elevation curve and the decay of community similarity with elevation: closely related families share community patterns within the three major taxa. Phylogenetic influences are partly explained by similarities among families in conserved traits defining body plan and interactions, implying a scaling of phylogenetic effects from the organismal to the community level. Consequently, the phylogenetic signal in community-level patterns informs about how the historical legacy of a taxon and shared responses among related taxa to similar environments contribute to community assembly and diversity patterns.
Free log-likelihood as an unbiased metric for coherent diffraction imaging
Authors: Favre-Nicolin Vincent , Leake Steven , Chushkin Yuriy 
Published: February 2020

AbstractCoherent Diffraction Imaging (CDI), a technique where an object is reconstructed from a single (2D or 3D) diffraction pattern, recovers the lost diffraction phases without a priori knowledge of the extent (support) of the object. The uncertainty of the object support can lead to over-fitting and prevents an unambiguous metric evaluation of solutions. We propose to use a ‘free’ log-likelihood indicator, where a small percentage of points are masked from the reconstruction algorithms, as an unbiased metric to evaluate the validity of computed solutions, independent of the sample studied. We also show how a set of solutions can be analysed through an eigen-decomposition to yield a better estimate of the real object. Example analysis on experimental data is presented both for a test pattern dataset, and the diffraction pattern from a live cyanobacteria cell. The method allows the validation of reconstructions on a wide range of materials (hard condensed or biological), and should be particularly relevant for 4th generation synchrotrons and X-ray free electron lasers, where large, high-throughput datasets require a method for unsupervised data evaluation.