bluuebunny/crossref_metadata_2025_split huggingface dataset:
The prognostic value of platelet-to-lymphocyte ratio on the long-term renal survival in patients with IgA nephropathy
Authors: Chang Dan , Cheng Yichun , Luo Ran , Zhang Chunxiu , Zuo Meiying , Xu Yulin , Dai Wei , Li Yueqiang , Han Min , He Xiaofeng , Ge Shuwang , Xu Gang 
Published: October 2020

AbstractPurposePlatelet-to-lymphocyte ratio (PLR) was established showing the poor prognosis in several diseases, such as malignancies and cardiovascular diseases. But limited study has been conducted about the prognostic value of PLR on the long-term renal survival of patients with Immunoglobulin A nephropathy (IgAN).MethodsWe performed an observational cohort study enrolling patients with biopsy-proven IgAN recorded from November 2011 to March 2016. The definition of composite endpoint was eGFR decrease by 50%, eGFR < 15 mL/min/1.73 m2, initiation of dialysis, or renal transplantation. Patients were categorized by the magnitude of PLR tertiles into three groups. The Kaplan–Meier curves and multivariate Cox models were performed to determine the association of PLR with the renal survival of IgAN patients.Results330 patients with a median age of 34.0 years were followed for a median of 47.4 months, and 27 patients (8.2%) had reached the composite endpoints. There were no differences among the three groups (PLR < 106, 106 ≤ PLR ≤ 137, and PLR > 137) in demographic characteristics, mean arterial pressure (MAP), proteinuria, and estimated glomerular filtration rate (eGFR) at baseline. The Kaplan–Meier curves showed that the PLR > 137 group was significantly more likely to poor renal outcomes than the other two groups. Using univariate and multivariate cox regression analyses, we found that PLR > 137 was an independent prognostic factor for poor renal survival in patients with IgAN. Subgroup analysis revealed that the PLR remained the prognostic value for female patients or patients with eGFR less than 60 mL/min/1.73 m2.ConclusionsOur results underscored that baseline PLR was an independent prognostic factor for poor renal survival in patients with IgAN, especially for female patients or those patients with baseline eGFR less than 60 mL/min/1.73 m2.
Simultaneous Differential Thermal Analysis and Thermogravimetric Analysis of Si-30B Alloy
Authors: Homa M. , Sobczak N. , Hodor K. , Gezgin S. 
Published: October 2020

AbstractThis article focuses on the experimental determination of the transformation temperature of Si-30B alloy in the temperature range of 25-1820 °C in a flowing gas atmosphere (He, 99.9992%) carried out by simultaneous differential thermal analysis and thermogravimetric analysis (DTA–TG) using a graphite container. The DTA curve during heating showed the presence of two critical temperatures, i.e., T = 1380.7 °C and T = 1532.0 °C. The first one corresponds to the melting point of a eutectic system (Si + SiB6). The high-temperature interaction and reactivity between the alloy and the container during DTA–TG test were evaluated by scanning electron microscopy coupled with energy-dispersive x-ray analysis. The results have demonstrated that the graphite container reacts with both liquid silicon and boron dissolved in liquid constituent of the alloy to form SiC and B4C, respectively.
Assessment model of water harvesting and storage location using GIS and remote sensing in Al-Qadisiyah, Iraq
Authors: Al-Khuzaie Marwah M. , Janna Hussein , Al-Ansari Nadhir 
Published: October 2020

AbstractOne of the important steps towards optimizing land productivity and water availability for the semi-arid and arid areas is the identification of potential sites for water harvesting. Therefore, this paper uses the Geographical Information System (GIS) techniques to select the optimized sites for water harvesting in Al-Qadisiyah Governorate, Iraq. Geographic water management capabilities are applied as a spatial analysis model. Data from global data repositories are retrieved followed by rescaling them to a spatial resolution to acquire a manageable input data set. The Soil Conservation Service Curve Number (SCS-CN) model is used to calculate the potential runoff as an intermediate input. Multi-Criteria Evaluation techniques are adopted to identify the relative importance and suitability levels of the input parameters set to manage the water supply. The suitability for identifying irrigation pond and dam location(s) was considered in this study. To achieve this goal, the criteria for eligibility for water harvesting areas have been completed on the basis of the conditions in the study methods. Based on the hydrological and geomorphological standards of the study area, suitable sites for harvest areas were identified and it was divided into four classes in terms of their suitability for water harvesting, namely very low, low, moderate, and high suitable for water harvesting. It can be concluded that the findings of this research can be used to assist in water resources management as an efficient planning tool to ensure sustainable development of the water in Iraq who suffers from water shortages.
Victims or perpetrators: contribution and response of insects to forest diebacks and declines
Authors: Sallé Aurélien , Bouget Christophe 
Published: October 2020

AbstractKey messageUnprecedented forest declines and diebacks are expected worldwide in response to global change. Insects can trigger or contribute to these disturbances, which can in turn have either beneficial or detrimental retroactive cascading effects on insect communities. However, we are still unsure of the effects that pests will have on these disturbances in the future, and new biodiversity and pest management strategies still need to be put into place. Several recent contributions to Annals of Forest Science address these issues.
Effects of Traffic Loads and Track Parameters on Rail Wear: A Case Study for Yenikapi–Ataturk Airport Light Rail Transit Line
Authors: Yılmaz Sönmez Hazal , Öztürk Zübeyde 
Published: October 2020

AbstractThe aim of this study is to investigate the effects of traffic loads and track parameters, including track curvature, superelevation, and train speed, on vertical and lateral rail wear. The Yenikapi–Ataturk Airport Light Rail Transit (LRT) line in Istanbul was selected as a case study, and rail wear measurements were carried out accordingly. Passenger counts were performed in all wagons of the train on different days and time intervals to calculate the number of passengers carried in track sections between stations regarding traffic loads on the LRT line. Values of traffic load, track curvature, superelevation, and speed were determined for each kilometer where measurements of rail wear were conducted. A multiple linear regression analysis (MLRA) method was used to identify effective parameters on rail wear. Independent variables in MLRA for both vertical and lateral wear include traffic load, track curvature, superelevation, and train speed. The dependent variables in MLRA for vertical and lateral wear are the amount of vertical and lateral wear, respectively. The correlation matrix of the dependent and independent variables was analyzed before performing MLRA. Multicollinearity tests and cross-validation analyses were conducted. According to the results of MLRA for vertical and lateral wear, the obtained coefficients of determination indicate that a high proportion of variance in the dependent variables can be explained by the independent variables. Traffic load has a statistically significant effect on the amount of vertical and lateral rail wear. However, track curvature, superelevation, and train speed do not have a statistically significant effect on the amount of vertical or lateral rail wear.
Sampling on networks: estimating spectral centrality measures and their impact in evaluating other relevant network measures
Authors: Ruggeri Nicolò , De Bacco Caterina 
Published: October 2020

AbstractWe perform an extensive analysis of how sampling impacts the estimate of several relevant network measures. In particular, we focus on how a sampling strategy optimized to recover a particular spectral centrality measure impacts other topological quantities. Our goal is on one hand to extend the analysis of the behavior of TCEC (Ruggeri and De Bacco, in: Cherifi, Gaito, Mendes, Moro, Rocha (eds) Complex networks and their applications VIII, Springer, Cham, pp 90–101, 2020), a theoretically-grounded sampling method for eigenvector centrality estimation. On the other hand, to demonstrate more broadly how sampling can impact the estimation of relevant network properties like centrality measures different than the one aimed at optimizing, community structure and node attribute distribution. In addition, we analyze sampling behaviors in various instances of network generative models. Finally, we adapt the theoretical framework behind TCEC for the case of PageRank centrality and propose a sampling algorithm aimed at optimizing its estimation. We show that, while the theoretical derivation can be suitably adapted to cover this case, the resulting algorithm suffers of a high computational complexity that requires further approximations compared to the eigenvector centrality case. Main contributions (a) Extensive empirical analysis of the impact of the TCEC sampling method (optimized for eigenvector centrality recovery) on different centrality measures, community structure, node attributes and statistics related to specific network generative models; (b) extending TCEC to optimize PageRank estimation.
Dynamic Dossier in the Cloud: A Sociotechnical Architecture for a Real-Time and Metrics-Based Data Tracking System with Gene and Cell Therapies as a Case Study
Authors: Nam Kevin , Larholt Kay , Hirsch Gigi , Beninger Paul , Fritsche David , Shoda Diane , Ferguson John , Bourgeois Florence T. , Palmer Donna , Katz Karen , Courtney Matt W. 
Published: October 2020

Abstract
Background
Data sharing among stakeholders in the development, access, and use of drug therapies is critical but the current system and process are inefficient.

Methods
We take a Systems Engineering approach with a realistic use case to propose a scalable design for multi-stakeholder data sharing.

Results
We make three major contributions to the drug development and healthcare communities: first, a methodology for developing a multi-stakeholder data sharing system, with its focus on high-level requirements that influence the design of the system architecture and technology choice; second, the development of a realistic use case for long-term patient and therapy data tracking and sharing in the use of potentially curative and durable gene and cell therapies. Further, a bridge for the ‘awareness gap’ was found between the payer (Payer is organization which takes care of financial and operational aspects (which include insurance plans, provider network) of providing health care to US citizens. Or refer to health care insurers.) and the regulator communities by illustrating the common data tracking needs, which highlights the need for coordinated data activities; and third, a proposed system architecture for scalable, multi-stakeholder data sharing. Next steps are briefly discussed.

Conclusion
We present a system design for multiple stakeholders such as the payer, the regulator, the developer (drug manufacturer), and the healthcare provider to share data for their decision-making. The stakeholder community would benefit from collaboratively moving the system development proposal forward for efficient and cost-effective data sharing.
Ectopic Banking and Implantation of an Amputated Hand
Authors: Liaghat Omid , Shabbooie Zohre 
Published: October 2020

Abstract

Background
Ectopic banking includes techniques and indications used to bank amputated body parts for later replantation when a body part is amputated in its entirety. Immediate replantation is sometimes impossible due to hemodynamic instability, soft tissue loss, and extensive contamination of the amputated part. The first case of temporary ectopic banking of hand implantation was reported in 2015 by Xu Zhang in China which was not completely successful. The first replantation was reported almost 54 years ago, followed by a limited number of similar cases that were not successful. Xu could not restore the useful function of the replanted hand.

Purpose
In this study, we reported a case of hand replantation by the banking technique.

Method
We carried out a hand replantation by the banking technique using the right ankle as the recipient site.

Result
We restored the useful function of the amputated part and evaluated the function with standard tests.

Conclusion
Using right ankle as recipient site in ectopic banking can be a useful approach which helps and ensures the researchers and surgeons to decide if they intend to use this method.
The Berlin Acute Trauma Care Instrument Set (BATMIN) – A Selected Combination of Surgical Instruments for Damage Control and Hemostasis Surgery in Severe Acute Trauma
Authors: Märdian Sven , Klein Fitz , Solarek André , Nonnen Lena , Cwojdzinski Detlef , Auhuber Thomas , Lembke Vanessa 
Published: October 2020

AbstractA lack of sterile surgical instrument sets for damage control surgeries of severely injured patients became evident in a series of in-hospital mass casualty trainings in the German capital of Berlin. Moreover, the existing instrument trays contained mostly specialized instruments for elective interventions and were not well composed for the treatment of poly-traumatized patients. After a literature search on the most common injury patterns in Mass Casualty Incidents (MCIs), an expert group of surgeons from different disciplines designed an optimized instrument set. A set of 194 instruments was assembled and distributed into two containers. These 2 sets were subjected to a 6-month trial phase in our hospital, and the evaluation of usability was subsequently analyzed through feedback forms administered to the staff. After analysis of the feedback sheets, only minor alterations had to be incorporated. The Berlin Acute Trauma Care Instrument Set (BATMIN) was then made available by the state of Berlin to Berlin Hospitals providing acute trauma care. Out of the need to be prepared for mass casualties, we created an instrument set suitable for the damage control surgery of severely injured patients in individual care and MCIs.
Lust for life: coping with tuberculosis in late nineteenth-century Europe
Authors: Hakosalo Heini 
Published: October 2020

AbstractThe paper uses the correspondence of three Finns – Elias Erkko, Henrik Erkko and Hilda Asp – to analyse the conceptual and practical means with which late nineteenth-century-educated Europeans coped with ill health in general and tuberculosis in particular. While the need to gain control over (the threat of) disease may well be universal, the specific coping methods are historical and context-specific. They are both conceptual and practical, both individual and collective. The paper focuses on the 1880s and 1890s, a period when tuberculosis provided an especially lucrative subsector of the booming European medical marketplace. Sanatorium treatment was still only one among many treatment options, and the theory of the bacterial causation of tuberculosis was far from being universally accepted. The paper charts the options available for people suffering from pulmonary tuberculosis and analyses the eclectic, sometimes idiosyncractic, ways that they combined elements from different conceptual scripts and therapeutic traditions.
Duobagou Permian–Triassic granites from the Dunhuang orogenic belt, NW China: implications for the tectonic evolution of the southernmost Central Asian Orogenic Belt
Authors: Wang Zhendong , Zhang Yuanyuan , Yu Xiangjiang , Guo Zhaojie 
Published: October 2020

AbstractThe Duobagou Permian–Triassic granites of the Dunhuang orogenic belt are of great importance in understanding the tectonic evolution of the southernmost Central Asian Orogenic Belt. LA-ICP-MS U–Pb zircon ages indicate that Permian–Triassic granitic intrusions from the Duobagou area formed at 276–274 Ma and 246 ± 1 Ma. These granites have high SiO2, Na2O and K2O, but low Al2O3, CaO and MgO contents and belong mainly to the high-K calc-alkaline I-type granite series. Based on whole-rock geochemistry and Sr–Nd and zircon Hf isotopes, the Duobagou Permian–Triassic granites were dominantly derived from the partial melting of lower continental crust formed during late Palaeoproterozoic to Mesoproterozoic times in a post-collisional extensional setting. Permian granites with zircon ϵHf(t) values of −5.4 to +3.1 and Hf model ages of TDM2= 1.14–1.70 Ga indicate the involvement of a mantle component in their petrogenesis. Triassic granites with higher zircon ϵHf(t) values (+0.5 to +3.8) and TDM2= 1.08–1.31 Ga suggest more juvenile sources caused by a greater contribution of mantle-derived melts, indicating a significant crustal growth. Regional extension from lithospheric delamination and heating from asthenospheric upwelling were proposed to have triggered the partial melting of lower crust, resulting in the generation of the Permian–Triassic magmatism. This may have been the mechanism for the significant crustal growth during Permian and Triassic times in the southernmost Central Asian Orogenic Belt.
N. T. Wright and Paul’s Supersessionism: A Response to Kaminsky and Reasoner
Authors: Bird Michael F. 
Published: October 2020

AbstractJoel Kaminsky and Mark Reasoner offered a concerted critique of N. T. Wright’s account of Israel’s election as well as Wright’s description of the apostle Paul’s messianic atonement theology. They allege that Wright treats Israel’s election as instrumental rather than intrinsic and his exegesis of Rom 5:20‒21 results in a rehearsal of anti-Jewish tropes. This essay responds to them by 1) claiming that many of their criticisms are inaccurate representations of Wright’s views; 2) defending a missional perspective of Israel’s view of election; 3) asserting that Wright’s reading of Rom 5:20 about the Torah multiplying sin within Israel is neither immoral, nor implausible, nor idiosyncratic; and 4) offering some final thoughts about Wright and Jewish-Christian relations.
Redescription and molecular characterization of Crenidens macracanthus Günther, 1874 (Pisces: Sparidae), and first record of C. indicus Day, 1873 in the eastern Indian Ocean
Authors: Roul Subal Kumar , Jeena N. S. , Ghosh Shubhadeep , Rohit Prathibha 
Published: October 2020

AbstractCrenidens macracanthus was originally described in 1874 based on a single specimen collected from Chennai (Madras), south-east coast of India. In 1875, the species was synonymized with C. indicus without citing any valid reason. Since then, no taxonomic studies have been attempted for the genus Crenidens, except in 2013 the species was resurrected from synonymy and redescribed as a valid species based on the holotype and non-type specimen. In view of the fact that C. macracanthus is a poorly known species, it is redescribed based on examination of 30 additional specimens of 105.8–162.2 mm SL, collected from Puri, Odisha, north-east coast of India (Bay of Bengal) from 2017–2019, using morphological and molecular examinations. Our study provides a detailed morphological description, first colour photographs and phylogenetic analysis using COI barcodes of the species. The study has expanded the range in several morpho-meristic characters in comparison with the type and non-type specimens described earlier. The species in fresh condition can be easily distinguished from its two congeners (C. crenidens and C. indicus) by the yellowish tip of the lower caudal-fin lobe. Our study has also extended the distribution range of C. indicus (previously known only from the north-eastern Arabian Sea) to the eastern Indian Ocean, based on examination of a preserved specimen collected from Tuticorin, Tamil Nadu.
From Prohibition to Liquor Dispensaries: Explaining the Rise and Fall of State and Municipal Liquor Stores, 1891–1907
Authors: LEWIS MICHAEL 
Published: October 2020

AbstractThis article investigates the reasons for the adoption and rejection of liquor dispensaries in the years prior to the adoption of national prohibition in the United States. Southern municipalities were the primary dispensary locations, largely due to the permissiveness of local option laws in the South. Municipalities with dispensaries were often retreating from prohibition and dispensary supporters argued that publically run liquor stores were the next best thing. Beyond the South, states that explored dispensary adoption also were those repealing prohibition laws, suggesting a larger pattern whereby prohibition preceded dispensaries rather than following them.
The Shifting Politics of Public Services: Discourses, Arguments, and Institutional Change in Sweden, c. 1620–2000
Authors: LINNARSSON MAGNUS , HALLENBERG MATS 
Published: October 2020

AbstractThis article analyses the inherent conflict between public and private interest from a long time-perspective, using the example of Sweden from 1620 to 2000. The main argument is that there have been two equally decisive historical shifts in the political discourse on how to organize public services in the past: First, a shift from an early modern patriarchal discourse to a more expansive articulation of publicness during the nineteenth century. Second, a shift toward privatization and deregulation in the late twentieth century. Both these shifts must be considered to fully explain the changing forms of public organization up to the present day. Theoretically, the concept of “publicness” is used to explain the political discourses on the organization of public services. Drawing on three discursive chains, the argument is that the political development was affected by the politicians’ conception of the political community, the form of organization, and by perceptions of values such as equal access and modernity. Our results demonstrate how and why political arguments for or against private service providers have motivated profound changes in the way public services are perceived of and organized.
A patient with respiratory toxigenic diphtheria in Greece after more than 30 years
Authors: Georgakopoulou T. , Tryfinopoulou K. , Doudoulakakis A. , Nikolaou F. , Magaziotou I. , Flountzi A. , Fry N. K. , Litt D. J , Damala M. , Spiliopoulou I. , Liatsi-Douvitsa E. , Lebessi E. , Panayiotakopoulos G. , Tsolia M. , Saroglou G. , Theodoridou M. , Tsiodras S. , Efstratiou A. 
Published: October 2020

Abstract
The introduction of treatment and systematic vaccination has significantly reduced diphtheria mortality; however, toxigenic strains continue to circulate worldwide. The emergence of an indigenous diphtheria case with fatal outcome in Greece, after 30 years, raised challenges for laboratory confirmation, clinical and public health management. Toxigenic Corynebacterium diphtheriae was isolated from an incompletely vaccinated 8-year-old boy with underlying conditions. The child passed away due to respiratory distress syndrome, before the administration of diphtheria antitoxin (DAT). All close contacts in family, school and hospital settings were investigated. Pharyngeal swabs were obtained to determine asymptomatic carriage. Chemoprophylaxis was given for 7 days to all close contacts and a booster dose to those incompletely vaccinated. Testing revealed a classmate, belonging to a subpopulation group (Roma), and incompletely vaccinated, as an asymptomatic carrier with an indistinguishable toxigenic strain (same novel multilocus sequence type, designated ST698). This case highlights the role of asymptomatic carriage, as the entry of toxigenic strains into susceptible populations can put individuals and their environment at risk. Maintenance of high-level epidemiological and microbiological surveillance, implementation of systematic vaccination in children and adults with primary and booster doses, availability of a DAT stockpile, and allowing timely administration are the cornerstone to prevent similar incidents in the future.