bluuebunny/crossref_metadata_2025_split huggingface dataset:
GUBENG STATION RAILWAY INFRASTRUCTURE PERFORMANCE ACCORDING TO USER PERCEPTION
Authors: Sulastri Dwi , Wahyuni Atik , Mudjanarko Sri Wiwoho 
Published: December 2020

<pre>Gubeng Station is the most populous station of 52 stations that enter the work area of PT KAI </pre><pre>Daop 8 Surabaya, with 978,346 train passengers in January 2019, where this number is the highest number </pre><pre>of train passengers for 3 years recorded at Gubeng station. Gubeng Station is also very unique, </pre><pre>because it is located at a height of 5 meters and has two functionally different sides. The west side </pre><pre>building is used for the departure and arrival of economy and express trains, while the east side </pre><pre>building is for the departure and arrival of business and executive trains. This functional difference </pre><pre>needs to be a study of the provision of infrastructure/facilities available at the Gubeng station </pre><pre>whether it meets the minimum train service standards and has provided services/satisfaction and the </pre><pre>importance of the existing facilities at the Gubeng station according to the train user perception. </pre><pre>The method used is importance performance analysis (IPA) and the conclusion is that satisfaction </pre><pre>and importance of the existing facilities at Gubeng station according to the train user perception obtained </pre><pre>a satisfaction value of 2.48 which means that they still do not get maximum service and the average </pre><pre>value of interest is 4.57 which means that the existing facilities at Gubeng station are needed by train </pre><pre>passengers.</pre><pre> </pre>
MEMBANGUN SISTEM FLEXIBLE BUDGETING DAN PENDAMPINGAN KEBERSIHAN MUSHOLA NURUL HUDA SAAT PANDEMI COVID19
Authors: Safitri Winda , Degita Azis Azolla 
Published: December 2020

Mushola sebagai tempat ibadah, sudah sepatutnya umat Islam menjaga kebersihan mushola dan merawat dengan baik dan bersih sehingga jamaah yang masuk kedalamnya merasa nyaman dan damai serta dapat melakukan ibadah dengan khusyuk. Dimasa pandemi COVID -19 kebersihan mushola di wajibkan agar terhindar dari virus. Mushola yang terjaga kebersihannya akan berpengaruh besar kepada orang-orang yang melakukan ibadah ditempat itu dan mereka yang beribadah didalamnya akan memperoleh ketenangan dan kekhusyuaan. Mushola yang di tujukan untuk melaksanakan pengabdian yaitu Mushola Nurul Huda yang terletak di Dukuh Cibogo rt 02/rw 03 Desa Cikeusal Kidul Kecamatan Ketanggungan Kabupaten Brebes. Selain kebersihan mushola, terdapat cara mengatur flexible budgeting yang merupakan bentuk laporan untuk menunjukkan estimasi besarnya revenue dan cost yang seharusnya pada tingkat actual aktivitas tertentu selama periode. Dengan demikian, setiap anggaran yang dikeluarkan untuk kepentingan mushola dibentukan laporan berupa angaran flexible agar menghitung setiap anggaran yang dibutuhkan dapat dihitung dengan mudah dan efisien.
DIGITALISASI WARUNG SEMBAKO DAN TERINTEGRASI DENGAN PAYMENT GATEWAY BERBASIS SYARIAH
Authors: Riswantio Ahmad , Devi Abrista 
Published: December 2020

Mitra dalam KKN Gagasan Tulis Mandiri ini adalah Usaha Mikro Kecil dan Menengah (UMKM) yang bergerak dalam bidang usaha retail atau warung sembako di Bantar Kemang Kota Bogor. UMKM yang menjadi mitra pengabdian ini belum lama membuka usahanya di bidang retail dan dari segi pemasarannya masih menggunakan cara yang konvensional. Karena itu UMKM ini perlu diberikan pelatihan mengenai digital marketing agar pemasarannya dapat lebih baik dan dapat memperluas cakupan pasarnya serta dapat menunjang kegiatan penjualan yang lebih baik. Selain itu, UMKM ini pun diberikan bantuan dalam membuat akun bisnis berupa Google Bisnis, Kerja sama dengan mitra yaitu WARKO Platform usaha retail online dan Mengintegrasikan dengan Payment Gateway Syariah, dan bantuan cara penggunaannya. Luaran atau hasil yang didapatkan adalah akun Google Bisnis, bermitra dengan WARKO, integrasi dengan Payment Gateway, dan artikel ilmiah yang diterbitkan dalam jurnal nasional. Metode yang digunakan dalam hal ini adalah ceramah, pendampingan dalam membuat akun, bermitra dengan warko dan mengitegrasikan dengan payment gateway, dan penyuluhan penggunaan sistem yang telah dibuat tersebut. Hasil dari pengabdian ini adalah ilmu dalam melakukan pemasaran secara digital dengan memanfaatkan teknologi yang telah ada untuk meluaskan target pasar, dan untuk membiasakan dalam new normal.
Communicative language teaching in reading comprehension
Authors: Yucailla Tixi Juan Elías 
Published: December 2020

Introducción. Generalmente se cree que la enseñanza comunicativa del lenguaje (ECL) se utiliza para enseñar el lenguaje con fines de comunicación e interacción. Por lo tanto, parece ser más adecuada para desarrollar la habilidad de hablar. No se ha explorado suficientemente la posibilidad de aplicar (ECL) en el desarrollo de otras habilidades como la comprensión lectora. Objetivo. El propósito de esta revisión de bibliográfica es examinar la enseñanza comunicativa de la lengua y su impacto en la comprensión lectora, presentando un caso a consideración en la Unidad Educativa Liceo Policial Chimborazo. Metodología. Se realizaron búsquedas en dos bases de datos electrónicas con una limitación de cuarenta años para reflejar la información más relevante. También se examinaron listas de investigaciones relevantes. Se seleccionaron un total de 32 artículos para su revisión. Dos temas encabezan la revisión de la literatura: "Enseñanza comunicativa de la lengua " y "Comprensión lectora". Resultados. Se encontró que la enseñanza comunicativa de la lengua le da al maestro la oportunidad de diseñar programas para explorar otros aspectos del lenguaje como la lectura. Conclusiones. Con base en la literatura revisada y su discusión anterior, se concluye que, aunque la enseñanza comunicativa de la lengua ha sido criticada por enfocarse más en el aspecto comunicativo del aprendizaje de lenguas, es probable que este método en el Ecuador refuerce las tasas de rendimiento académico de la mayoría de los estudiantes y mejore la tasa de lectura general del país.
Robótica Educacional como metodologia motivadora no ensino de lógica de programação na Educação Profissional e Tecnológica
Authors: Ramos Bruno Amorim , Moraes Eduardo Cardoso 
Published: December 2020

Este artigo objetiva apresentar o uso do produto educacional Robôcactus, resultante da dissertação do primeiro autor, como ferramenta teórico-metodológica associada a robótica educacional e a plataforma Arduino na Educação Profissional e Tecnológica (EPT). Para tanto, este trabalho recorre a metodologia da pesquisa-ação participante, as metodologias ativas de Sala da Aula Invertida (SAI) e a Aprendizagem Baseada em Projetos (PBL). Diante as dificuldades e desmotivação dos discentes no componente de lógica de programação, foi criada uma metodologia que visa mitigar este impacto através da realização uma oficina de robótica educacional que vislumbra contribuir a formação do pensamento crítico e conhecimento técnico através da práxis, fatores importantíssimos para desenvolvimento do profissional do século XXI. O levantamento de dados conta com questionários semiestruturados e a análise de conteúdo revela a experiência positiva da utilização da robótica como agente motivador tecnológico no âmbito escolar.
Integrated Analysis of Immunity- and Ferroptosis-Related Biomarker Signatures to Improve the Prognosis Prediction of Hepatocellular Carcinoma
Authors: Du Xuanlong , Zhang Yewei 
Published: December 2020

BackgroundHepatocellular carcinoma (HCC) is a common malignant tumor with high mortality and poor prognoses around the world. Ferroptosis is a new form of cell death, and some studies have found that it is related to cancer immunotherapy. The aim of our research was to find immunity- and ferroptosis-related biomarkers to improve the treatment and prognosis of HCC by bioinformatics analysis.MethodsFirst, we obtained the original RNA sequencing (RNA-seq) expression data and corresponding clinical data of HCC from The Cancer Genome Atlas (TGCA) database and performed differential analysis. Second, we used immunity- and ferroptosis-related differentially expressed genes (DEGs) to perform a computational difference algorithm and Cox regression analysis. Third, we explored the potential molecular mechanisms and properties of immunity- and ferroptosis-related DEGs by computational biology and performed a new prognostic index based on immunity- and ferroptosis-related DEGs by multivariable Cox analysis. Finally, we used HCC data from International Cancer Genome Consortium (ICGC) data to perform validation.ResultsWe obtained 31 immunity (p &lt; 0.001)- and 14 ferroptosis (p &lt; 0.05)-related DEGs correlated with overall survival (OS) in the univariate Cox regression analysis. Then, we screened five immunity- and two ferroptosis-related DEGs (HSPA4, ISG20L2, NRAS, IL17D, NDRG1, ACSL4, and G6PD) to establish a predictive model by multivariate Cox regression analysis. Receiver operating characteristic (ROC) and Kaplan–Meier (K–M) analyses demonstrated a good performance of the seven-biomarker signature. Functional enrichment analysis including Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) revealed that the seven-biomarker signature was mainly associated with HCC-related biological processes such as nuclear division and the cell cycle, and the immune status was different between the two risk groups.ConclusionOur results suggest that this specific seven-biomarker signature may be clinically useful in the prediction of HCC prognoses beyond conventional clinicopathological factors. Moreover, it also brings us new insights into the molecular mechanisms of HCC.
Anesthesia-Sepsis-Associated Alterations in Liver Gene Expression Profiles and Mitochondrial Oxidative Phosphorylation Complexes
Authors: Osuru Hari Prasad , Paila Umadevi , Ikeda Keita , Zuo Zhiyi , Thiele Robert H. 
Published: December 2020

Background: Hepatic dysfunction plays a major role in adverse outcomes in sepsis. Volatile anesthetic agents may protect against organ dysfunction in the setting of critical illness and infection. The goal of this study was to study the impact of Sepsis-inflammation on hepatic subcellular energetics in animals anesthetized with both Propofol (intravenous anesthetic agent and GABA agonist) and Isoflurane (volatile anesthetic i.e., VAA).Methods: Sprague-Dawley rats were anesthetized with Propofol or isoflurane. Rats in each group were randomized to celiotomy and closure (control) or cecal ligation and puncture “CLP” (Sepsis-inflammation) for 8 h.Results: Inflammation led to upregulation in hepatic hypoxia-inducible factor-1 in both groups. Rats anesthetized with isoflurane also exhibited increases in bcl-2, inducible nitric oxide synthase, and heme oxygenase-1(HO-1) during inflammation, whereas rats anesthetized with Propofol did not. In rats anesthetized with isoflurane, decreased mRNA, protein (Complex II, IV, V), and activity levels (Complex II/III,IV,V) were identified for all components of the electron transport chain, leading to a decrease in mitochondrial ATP. In contrast, in rats anesthetized with Propofol, these changes were not identified after exposure to inflammation. RNA-Seq and real-time quantitative PCR (qPCR) expression analysis identified a substantial difference between groups (isoflurane vs. Propofol) in mitogen-activated protein kinase (MAPK) related gene expression following exposure to Sepsis-inflammation.Conclusions: Compared to rats anesthetized with Propofol, those anesthetized with isoflurane exhibit more oxidative stress, decreased oxidative phosphorylation protein expression, and electron transport chain activity and increased expression of organ-protective proteins.
Prognostic Performance of Albumin–Bilirubin Grade With Artificial Intelligence for Hepatocellular Carcinoma Treated With Transarterial Chemoembolization Combined With Sorafenib
Authors: Zhong Bin-Yan , Yan Zhi-Ping , Sun Jun-Hui , Zhang Lei , Hou Zhong-Heng , Yang Min-Jie , Zhou Guan-Hui , Wang Wan-Sheng , Li Zhi , Huang Peng , Zhang Shen , Zhu Xiao-Li , Ni Cai-Fang 
Published: December 2020

PurposeTo establish albumin-bilirubin (ALBI) grade-based and Child-Turcotte-Pugh (CTP) grade-based nomograms, as well as to develop an artificial neural network (ANN) model to compare the prognostic performance and discrimination of these two grades for hepatocellular carcinoma (HCC) treated with transarterial chemoembolization (TACE) combined with sorafenib as an initial treatment.MethodsThis multicenter retrospective study included patients from three hospitals between January 2013 and August 2018. In the training cohort, independent risk factors associated with overall survival (OS) were identified by univariate and multivariate analyses. The nomograms and ANN were established and then validated in two validation cohorts.ResultsA total of 504 patients (319, 61, and 124 patients from hospitals A, B, and C, respectively) were included. The median OS was 15.2, 26.9, and 14.8 months in the training cohort and validation cohorts 1 and 2, respectively (P = 0.218). In the training cohort, both ALBI grade and CTP grade were identified as independent risk factors. The ALBI grade-based and CTP grade-based nomograms were established separately and showed similar prognostic performance and discrimination when validated in the validation cohorts (C-index in validation cohort 1: 0.799 vs. 0.779, P = 0.762; in validation cohort 2: 0.700 vs. 0.693, P = 0.803). The ANN model showed that the ALBI grade had higher importance in survival prediction than the CTP grade.ConclusionsThe ALBI grade and CTP grade have comparable prognostic performance for HCC patients treated with TACE combined with sorafenib. ALBI grades 1 and 2 have the potential to act as a stratification factor for clinical trials on the combination therapy of TACE and systemic therapy.
Analysis of Emission Infrared Spectra of Protein Solutions in Low Concentrations
Authors: Penkov Nikita , Penkova Nadezda 
Published: December 2020

In this work, based on the method of infrared emission spectroscopy, the study of emission spectra of interferon-gamma (IFNγ) solution in a mixture or surrounded by three low-concentration solutions (IFNγ, antibodies to IFNγ, glycine buffer) or water control was performed. First of all, the solutions of low concentrations themselves were studied. It was shown that low-concentration solutions of IFNγ and antibodies to IFNγ had lower emission intensity in three spectral bands near 800, 1,300 and 2000 cm−1 compared to water control. Glycine buffer solution had a radiation level indistinguishable from that of the control. In this work, the effect of adding these low-concentration solutions to IFNγ (1 mg/ml) was compared to the effect of adding water control to IFNγ. All solutions or water were added in 10% (v/v). It was found that adding each of the three test solutions induced an increase in the radiation intensity of the IFNγ solution in the spectral range of 400–1700 cm−1 (compared to the IFNγ solution with control spike). It was also tested whether the radiation of the studied low-concentration solutions surrounding the IFNγ solution (1 mg/ml) affected the IFNγ radiation. The measurement results were compared to the data obtained for IFNγ surrounded by water control. All three solutions were found to exert a distant effect on the IFNγ solution (1 mg/ml), which was manifested in a decrease in the intensity of its radiation near 1,000 and 1,500 cm−1 compared to the control solution of IFNγ. Thus, the emission spectra of low-concentration aqueous solutions were measured for the first time, and differences in the emission spectra of the IFNγ solution depending on low-concentration additives and the environment were shown. The paper interprets the observed differences and discusses possible mechanisms underlying the observed phenomena.
Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal Endometriosis
Authors: Bazot Marc , Beldjord Selma , Jarboui Lamia , Ferrier Clement , Bendifallah Sofiane , Daraï Emile 
Published: December 2020

Objective: The aim of the study was to evaluate three-dimensional (3D) T2 MRI before and after vaginal opacification (VO) by gel (3DT2VO) and the additional value of 3DT1 with fat-suppression (3DT1FS) MRI in the diagnosis of vaginal endometriosis.Methods: In this study conducted from 2010 to 2013, 51 patients scheduled for surgical treatment of endometriosis underwent MRI 1 day before surgery. Three readers (novice, intermediate, expert) were asked to retrospectively diagnose vaginal endometriosis independently and blindly using four different readings (i.e., 3DT2, 3DT2VO, 3DT2 with 3DT1FS, 3DT2VO with 3DT1FS). Vaginal endometriosis diagnosis was positive on observation of a thickening of vaginal walls on 3DT2 with or without high-signal-intensity spots on 3DT2 and/or 3DT1FS. The reference standard was surgery and histology. Descriptive analysis, Chi-square test, and ROC curves were used for statistical analysis.Results: For all readers, the combination of 3DT2 and 3DT1FS significantly improved the diagnosis of vaginal endometriosis compared with 3DT2 (p = 0.002, p = 0.02, and p = 0.003). 3DT2VO significantly improved diagnosis for the intermediate reader (p = 0.01). High-signal-intensity spots on 3DT1FS had a sensitivity of 50–63.6%, specificity of 86.2–96.6%, and high positive likelihood ratios (14.5-Inf).Conclusion: 3DT2 in association with 3DT1FS appears to be the best 3D MRI protocol for the diagnosis of vaginal endometriosis, whatever the level of experience of readers. The additional value of 3DT2VO is variable among the readers.
Sistematización de los artículos de grado de las especializaciones en comunicación de la UAC
Authors: Rosero Molina Javier , Rodriguez Chaparro Darvis Rafael , Ramos Maldonado Carlos 
Published: December 2020

Los artículos de revisión, reflexión e investigación hacen parte de los requisitos de grado para los estudiantes de las especializaciones en Comunicación de la Universidad Autónoma del Caribe. Teniendo en cuenta el firme propósito del aseguramiento de la calidad de ambas especializaciones se hace necesario la sistematización y el análisis de los trabajos de grados, el ejercicio nos permite establecer con precisión las temáticas más y menos utilizadas, y los resultados serán pieza clave en aras de aportar a la elaboración de nuevos proyectos de grado y la contribución a la estructuración e implementación de nuevos contenidos curriculares definidos dentro de los hilos conceptuales en Gerencia de la Comunicación Organizacional y Gerencia de la Comunicación para el Desarrollo Social. Para la sistematización y análisis de los trabajos de grado se empleará el software estadístico para las ciencias sociales y humanas SPSS. A partir de ello, se identificaron áreas sobre las cuales es prudente profundizar con la intención de que se mejoren, como es la búsqueda constante y la calidad de la educación ofrecida en estos posgrados.
Risk Management SIMRS using OCTAVE-S Method and ISO/EIC 27001 Control Standards
Authors: Setiawan Ito 
Published: December 2020

Rumah sakit Wishnu Husada Banyumas sudah menerapakan teknologi informasi dalam proses pelayanan namun permasalah yang muncul dalam penerapan sistem informasi sering terjadi seperti human error, server bermasalah dan risiko lainya. Kurangnya dokumentasi dalam penanganan risiko mengakibatkan risiko yang sama sering terulang kembali dikemudian hari. Tujuan dari penelitian ini adalah melakukan evaluasi risiko menggunakan metode OCTAVE-S dan standar pengendalian mengacu pada ISO 27001 pada Rumah sakit. Penelitian ini adalah penelitian kualitatif dengan menggunakan pendekatan studi kasus. Metode pengumpulan data menggunakan studi literatur dan studi lapangan. Hasil yang dicapai dari penelitian ini yaitu mengetahui aset kritis sistem informasi berupa database server dan juga SIMRS, mengetahui ancaman terhadap aset kritis berupa belum adanya beberapa standar prosedur di 6 bagian praktek keamanan. Terdapat 6 praktek keamanan yang mendapat stoplight warna merah, 9 praktek keamanan stoplight warna kuning dan 1 praktek keamanan stoplight warna hijau mengacu pada metode OCTAVE-S. Rencana mitigasi risiko mengacu pada ISO 27001 untuk membantu pihak rumah sakit memetakan sesuai dengan penilaian praktek keamanan yang telah dilakukan
Meningkatkan Service Quality Usaha Laundry Menggunakan Throw-away Prototyping
Authors: Khalida Rakhmi 
Published: December 2020

Banyaknya pelanggan yang berkunjung setiap hari untuk menggunakan jasa laundry membuat pemilik laundry harus mengambil kebijakan untuk kemajuan usaha karena data pelanggan tidak terekam dengan baik, tepat, dan akurat dan tidak jarang juga pelanggan sering menghilangkan struk pembayaran untuk pengambilan pakaian, hal itu menyebabkan kesulitan bagi pegawai untuk menyerahkan pakaianya, selain itu informasi yang diberikan pegawai untuk mengambil pakaian sering tidak tepat, dan itu sangat merugikan pelanggan yang nanti akan berdampak pada usaha jasa laundry. Tujuan penelitian ini yaitu dapat merancang sistem informasi jasa laundry berbasis web untuk membantu meningkatkan kinerja pada admin dalam pembuatan laporan, dan membuat pemberitahuan bagi pelanggan dengan SMS gateway saat pakaiannya telah selesai di kerjakan. Pembuatan sistem informasi jasa laundry berbasib web ini menggunakan metode pengembangan software throw-away prototyping dengan tahapan analisis kebutuhan, pembuatan prototype, evaluasi prototype, spesifikasi system, program sistem, validasi system, dan instalasi aplikasi. Dalam pembuatan sistem informasi jasa laundry berbasi web ini menggunakan metode pengumpulan data berupa wawancara, pengamatan, dan studi pustaka. Sistem informasi jasa laundry dibutuhkan untuk mempermudah pencatatan dan pengolahan secara akurat dan realtime. Sistem ini membuat seluruh manajemen laundry menjadi efisien dan sistematis. Penggunaan SMS gateway pada sistem ini dapat melengkapi transaksi pengambilan pakaian apabila struk pembayaran hilang.
Las etnias centroamericanas durante la segunda mitad del siglo XX
Authors: Lizcano Fernández Francisco 
Published: December 2020

Short description:
This article is dedicated to the demographic levels and distribution of Central American ethnic groups: indigenous, mestizos, mulattos, creoles, garifunas and Asians. The study includes 7 countries: Belize, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica and Panama. Emphasis is placed on the Caribbean region of these countries, where ethnic diversity is the greatest.
Short description translated and adapted from the text by Michał Gilewski
Desafíos de las políticas interculturales en Chile: derechos indígenas y el desarrollo socioeconómico.
Authors: Castro Lucic Milka 
Published: December 2020

In this paper author analyzes de relation between the indigenous peoples and the institutions of the state, especially in the period of military dictatorship in Chile, dedicating special attention to the revival of the indigenous groups, what they expect basing on their legal rights, and what they encounter in practice.
Fragment translated and Adapted from Spanish text by Michal Gilewski