bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Systemic Concept of Contextual Truth
Authors: Bielecki Andrzej 
Published: October 2020

AbstractIn this paper the truth is studied in the frame of autonomous systems theory. The method of the truth verification is worked out in its functional aspect. The verification is based on comparison of the predicted inner state of the autonomous agent, that is the cognitive subject, to the achieved inner state of the agent. The state is achieved as the result of performing the action in the real world—the agent’s environment. The action design is created on the basis of the agent’s model of the world. The truth is defined as the adequacy of the model of the real world in the context of the goal that is assumed to be reached as the effect of the performed action. The concepts of the cognitive subject, the truth bearings and the knowledge are redefined. The classical problems of aletheiology and epistemology are discussed in the light of the proposed approach. The cybernetic construct of an autonomous agent allows the researcher to consider a wide class of cognitive entities, which, in the previous approaches, have been limited only to human beings as cognitive subjects.
A qPCR method for distinguishing biomass from non-axenic terrestrial cyanobacteria cultures in hetero- or mixotrophic cultivations
Authors: Walther Jakob , Schwarz Anna , Witthohn Marco , Strieth Dorina , Muffler Kai , Ulber Roland 
Published: October 2020

AbstractThe cultivation of cyanobacteria with the addition of an organic carbon source (meaning as heterotrophic or mixotrophic cultivation) is a promising technique to increase their slow growth rate. However, most cyanobacteria cultures are infected by non-separable heterotrophic bacteria. While their contribution to the biomass is rather insignificant in a phototrophic cultivation, problems may arise in heterotrophic and mixotrophic mode. Heterotrophic bacteria can potentially utilize carbohydrates quickly, thus preventing any benefit for the cyanobacteria. In order to estimate the advantage of the supplementation of a carbon source, it is essential to quantify the proportion of cyanobacteria and heterotrophic bacteria in the resulting biomass. In this work, the use of quantitative polymerase chain reaction (qPCR) is proposed. To prepare the samples, a DNA extraction method for cyanobacteria was improved to provide reproducible and robust results for the group of terrestrial cyanobacteria. Two pairs of primers were used, which bind either to the 16S rRNA gene of all cyanobacteria or all bacteria including cyanobacteria. This allows a determination of the proportion of cyanobacteria in the biomass. The method was established with the two terrestrial cyanobacteria Trichocoleus sociatus SAG 26.92 and Nostoc muscorum SAG B-1453-12a. As proof of concept, a heterotrophic cultivation with T. sociatus with glucose was performed. After 2 days of cultivation, a reduction of the biomass partition of the cyanobacterium to 90% was detected. Afterwards, the proportion increased again.
Heuristic techniques for modelling machine spinning processes
Authors: Stryczek Roman , Wyrobek Kamil 
Published: October 2020

AbstractIn spite of many efforts made a complete model of machine spinning processes, due to its complexity, multidimensionality of the decision space and the present state of knowledge, is unachievable. The paper addresses the issues of constructing a local process model to enable the search for a locally optimal course of the process, within a short time and with the cost as low as possible. Comparison was made between the theoretically well-grounded response surface designs method with a few approaches to the model construction based on intuitively understood heuristic bases justified by their successful practical applications. In order to determine a set of Pareto-optimal solutions for a discrete decision space, the durations of process execution were generated through a virtual simulation. In order to outline and justify the adopted solutions a comprehensive example of the practical construction of the machine spinning process model was presented, including its various versions. The results obtained were validated and evaluated. The main utilitarian conclusion is the indication whereby basing on a partial experiment plan it is possible, thanks to simple heuristic methods, to obtain Pareto-optimal solutions which are close to those obtained when the full experiment plan is carried out.
Field-synchronized Digital Twin framework for production scheduling with uncertainty
Authors: Negri Elisa , Pandhare Vibhor , Cattaneo Laura , Singh Jaskaran , Macchi Marco , Lee Jay 
Published: October 2020

AbstractResearch on scheduling problems is an evergreen challenge for industrial engineers. The growth of digital technologies opens the possibility to collect and analyze great amount of field data in real-time, representing a precious opportunity for an improved scheduling activity. Thus, scheduling under uncertain scenarios may benefit from the possibility to grasp the current operating conditions of the industrial equipment in real-time and take them into account when elaborating the best production schedules. To this end, the article proposes a proof-of-concept of a simheuristics framework for robust scheduling applied to a Flow Shop Scheduling Problem. The framework is composed of genetic algorithms for schedule optimization and discrete event simulation and is synchronized with the field through a Digital Twin (DT) that employs an Equipment Prognostics and Health Management (EPHM) module. The contribution of the EPHM module inside the DT-based framework is the real time computation of the failure probability of the equipment, with data-driven statistical models that take sensor data from the field as input. The viability of the framework is demonstrated in a flow shop application in a laboratory environment.
Small amplitude chimeras for coupled clocks
Authors: Dudkowski Dawid , Jaros Patrycja , Czołczyński Krzysztof , Kapitaniak Tomasz 
Published: October 2020

AbstractWe report the arise of small amplitude chimera states in three coupled pendulum clocks suspended on an oscillating base. Two types of chimeras are identified and described by the character of the behaviour of particular units (which can be both regular or irregular). The regions of the appearance of the dynamical patterns are determined and the scenarios of their coexistence with typical synchronization states are discussed. We investigate the chimeras’ basins of attraction, showing that the arise of complex dynamics is not straightforward and highly depends on the system’s parameters and the initial conditions. The latter is confirmed by the probability analysis, exhibiting the rare character of the observed attractors. The scenarios of bifurcations between the chimeric patterns are studied and supported using the energy balance method, which allows to describe the changes of the energy flows between particular nodes of the system. The results presented in this paper confirm the ones obtained for the previous models, extending the analysis with an additional degree of freedom.
3D-XGuide: open-source X-ray navigation guidance system
Authors: Vernikouskaya Ina , Bertsche Dagmar , Rottbauer Wolfgang , Rasche Volker 
Published: October 2020

AbstractPurposeWith the growing availability and variety of imaging modalities, new methods of intraoperative support have become available for all kinds of interventions. The basic principles of image fusion and image guidance have been widely adopted and are commercialized through a number of platforms. Although multimodal systems have been found to be useful for guiding interventional procedures, they all have their limitations. The integration of more advanced guidance techniques into the product functionality is, however, not easy due to the proprietary solutions of the vendors. Therefore, the purpose of this work is to introduce a software system for image fusion, real-time navigation, and working points documentation during transcatheter interventions performed under X-ray (XR) guidance.MethodsAn interactive software system for cross-modal registration and image fusion of XR fluoroscopy with CT or MRI-derived anatomic 3D models is implemented using Qt application framework and VTK visualization pipeline. DICOM data can be imported in retrospective mode. Live XR data input is realized by a video capture card application interface.ResultsThe actual software release offers a graphical user interface with basic functionality including data import and handling, calculation of projection geometry and transformations between related coordinate systems, rigid 3D-3D registration, and template matching-based tracking and motion compensation algorithms in 2D and 3D. The link to the actual software release on GitHub including source code and executable is provided to support independent research and development in the field of intervention guidance.ConclusionThe introduced system provides a common foundation for the rapid prototyping of new approaches in the field of XR fluoroscopic guidance. As a pure software solution, the developed system is potentially vendor-independent and can be easily extended to be used with the XR systems of different manufacturers.
On the 3-D Shape of Interlaced Regions in Sn-3Ag-0.5Cu Solder Balls
Authors: Daszki A. A. , Gourlay C. M. 
Published: October 2020

AbstractThe microstructure of Sn-Ag-Cu (SAC) solder joints plays an important role in the reliability of electronics, and interlaced twinning has been linked with improved performance. Here, we study the three-dimensional (3-D) shape of interlaced regions in Sn-3.0Ag-0.5Cu (SAC305) solder balls by combining serial sectioning with electron backscatter diffraction. In solder balls without large Ag3Sn plates, we show that the interlaced volume can be reasonably approximated as a hollow double cone with the common 〈100〉 twinning axis as the cone axis, and the 〈110〉 from all three twinned orientations making up the cone sides. This 3-D morphology can explain a range of partially interlaced morphologies in past work on 2-D cross-sections.
Why Does General QoL Tend to Worsen Over Time Following Septoplasty Even in the Absence of Worsening Nasal Symptoms?
Authors: Cantone Elena , Iengo Maurizio 
Published: October 2020

AbstractSeptoplasty is one of the most frequent surgical procedures performed by head and neck surgeons. Despite surgical correction, some patients are not satisfied with their postoperative outcomes. Only a few papers report data on the long-term quality of life of patients after septoplasty, and none over 36 months. This follow up study on 68 surgical procedures aims to evaluate the differences between short term and long-term quality of life after septoplasty using a disease specific quality of life questionnaire, the NOSE, and a general health status questionnaire, the SF-36. We found a statistically significant decrease of the total long-term SF-36 scores, but we did not find changes of the NOSE scores compared with the short-term scores. These results indicated that patients perceived a worsening of their quality of life after more than 36 months following septoplasty, even in the absence of specific nasal symptoms. We could speculate that the preoperative general health performance was erroneously attributed to specific nasal symptoms, probably incorrectly emphasized or that patients did not correctly remember the preoperative clinical status. This research pointed out the importance of patients’ selection and of a thorough evaluation of their preoperative expectations before surgical planning.
Cosmopolitan Democratic and Communicative Rights: The Danish Cartoons Controversy and the Right to Be Heard, Even Across Borders
Authors: Brown Alexander , Lægaard Sune 
Published: October 2020

AbstractDuring the Danish cartoons controversy in 2005–2006, a group of ambassadors to Denmark representing eleven predominantly Muslim countries requested a meeting with the Danish Prime Minister, Anders Fogh Rasmussen, to protest against the cartoons. Rasmussen interpreted their viewpoint as one of demanding limits to freedom of speech and he ignored their request for a meeting. Drawing on this case study, the article argues that it is an appropriate, and potentially effective, moral criticism of anyone who is in a position of political power—taking into account reasonable constraints of feasibility and practicality—that they have refused to receive information, ideas, or opinions from individuals, or their representatives, with dissenting viewpoints. The article also articulates one possible theoretical ground for such a moral criticism: that they could be violating a fundamental (cosmopolitan) moral right of people to submit information, ideas, or opinions to those who wield power over them and to be meaningfully heard—a right which can span state borders.
Phylogeography and potential glacial refugia of terrestrial gastropod Faustina faustina (Rossmässler, 1835) (Gastropoda: Eupulmonata: Helicidae) inferred from molecular data and species distribution models
Authors: Zając Kamila S. , Proćków Małgorzata , Zając Krzysztof , Stec Daniel , Lachowska-Cierlik Dorota 
Published: October 2020

AbstractFaustina faustina is a conchologically highly diverse forest gastropod with several morphological forms. It is a Carpathian species, but it also occurs in northern isolated localities, where it was probably introduced. We performed the first phylogeographic analysis of 22 populations, based on three molecular markers: COI, ITS-2, and 28S rRNA. Genetic data were complemented by paleo-distribution models of spatial occupancy during the Last Glacial Maximum to strengthen inferences of refugial areas. We discovered high genetic variability of COI sequences with p-distances between haplotypes ranged from 0.2 to 18.1% (6.3–16.6% between clades). For nuclear markers, a haplotype distribution pattern was revealed. Species distribution models indicated a few potential refugia in the Carpathians, with the most climatically stable and largest areas in the Southern Carpathians. In some climate scenarios, putative microrefugia were also predicted in the Western and Eastern Carpathians, and in the Apuseni Mts. Our results suggest the glacial in situ survival of F. faustina and its Holocene expansion in the Sudetes. Although our genetic data as well as shell phenotypes showed considerable variation within and between studied populations, the molecular species delimitation approaches still imply only one single species. Our study contributes to the understanding of the impact of processes on shaping contemporary population genetic structure and diversity in low-dispersal, forest species.
Linearly variable chord-extension morphing for helicopter rotor blades
Authors: Majeti Rohin K. , van der Wall Berend G. , Balzarek Christoph G. 
Published: October 2020

AbstractA new morphing concept called linearly variable chord extension was studied for its effectiveness in improving the efficiency of a helicopter rotor. Apart from chord extension itself, an additional feature which is deflection of the extended part of the chord resulting in an effective camber and additional twist to the airfoil, is also studied for its effect on rotor efficiency improvement. Trim analyses were carried out for various chord-extended rotors for hover as well as various forward flight velocities using DLR’s in-house comprehensive analysis code S4. Chord extension of up to 100% and chord-extension–deflection of up to 15° were considered. Results show that the linearly variable chord-extension concept is effective in reducing power requirement in both hover and forward flight. Deflection of the extended chord also helps reduce power requirement in hover, especially at higher blade loadings. However, the root torsional moments and hence, the pitch-link loads are seen to increase substantially for the morphed rotors.
An Inquiry into Success Factors for Post-disaster Housing Reconstruction Projects: A Case of Kerala, South India
Authors: Anilkumar Shyni , Banerji Haimanti 
Published: October 2020

AbstractThe 2004 Indian Ocean Tsunami triggered significant destruction to housing and related infrastructures across various coastal districts of south India. Research shows that tsunami reconstruction projects in Kerala experienced different degrees of success and failure. On this background, this study explored factors that contributed to the successful implementation of tsunami housing projects in Kerala by (1) consolidating various critical success factors (CSFs) for post-disaster reconstruction (PDR) projects under “project management success traits” through content analysis of existing literature; (2) deriving a conceptual model that envisages project success in PDR contexts; and (3) assessing the impacts of those success traits on tsunami housing projects using confirmatory factor analysis. Necessary data were gathered through a survey of various stakeholders involved in tsunami reconstruction projects in Kerala using structured questionnaires. The research revealed that PDR project success is attributed to critical dimensions of project management such as institutional mechanisms, reconstruction strategies, project implementation, and stakeholder management. A conceptual model with the interplay of project success, success traits, as well as their CSFs identified the project management actions that must be monitored during reconstruction. Since the project management approach is widely recognized for PDR projects, these success traits hold huge potential for effective organization and management of housing reconstruction projects. The study also helped to identify project management traits that need improvements for the successful implementation of post-disaster housing projects in Kerala. Thus the research findings can serve as a foundational study for formulating project management strategies appropriate to PDR projects in Kerala.
Associations of Objectively Measured Physical Activity and Sedentary Time with the Risk of Stroke, Myocardial Infarction or All-Cause Mortality in 70-Year-Old Men and Women: A Prospective Cohort Study
Authors: Ballin Marcel , Nordström Peter , Niklasson Johan , Nordström Anna 
Published: October 2020

Abstract
Objective
To study the associations of objectively measured physical activity (PA) and sedentary time (ST) with the combined outcome of incident stroke, myocardial infarction (MI) or all-cause mortality in older adults.

Methods
N = 3343 men and women aged 70 who participated in a health survey between 2012 and 2017 were included. Actigraph GT3X+ accelerometers were used to measure light-intensity PA (LPA), moderate-intensity PA (MPA) and ST for 1 week. Incident cases of cardiovascular disease (CVD) in terms of stroke or MI, and all-cause mortality were identified using national registers. Hazard ratios (HR) and 95% confidence intervals (CI) were estimated using multivariable-adjusted Cox regressions.

Results
During a mean follow-up of 2.7 years (0.1–5.6), there were 124 events of CVD or all-cause mortality. After adjusting for potential confounders and mediators, every 30-min/day increment in LPA was associated with 11% lower risk of CVD or all-cause mortality (HR 0.89, 95% CI 0.82–0.97), and every 30-min/day increment in MPA was associated with 36% lower risk (HR 0.64, 95% CI 0.48–0.84). Every 1-h/day increment in ST increased the risk of the outcomes by 33% (HR 1.33, 95% CI 1.14–1.56), although there was no significant association among participants who performed ≥ 30 min/day MPA (HR 1.11, 95% CI 0.82–1.50, P = 0.034 for interaction). None of the associations were modified by sex (P > 0.4 for all).

Conclusion
Objectively measured LPA and MPA are each associated with lower risk of stroke, MI or all-cause mortality in 70-year-old individuals, while ST is associated with increased risk. The greatest risk reduction is observed for MPA, which also appears to attenuate some of the increased risks associated with ST.
The Specificity of Dynamic Resistance of Existing Bridge Structures in Mining Areas
Authors: Mrozek Dawid , Mrozek Magdalena 
Published: October 2020

AbstractThe article presents the results of a dynamic resistance analysis of selected existing bridge structures. The numerical calculations performed with the use of THA (time history analysis) pertained to road and rail bridges of steel and concrete structures—not paraseismically designed. The purpose of the work was to determine the dynamic resistance of objects to the influence of paraseismic impacts resulting from mining operations. The specificity of performing calculations in this area of engineering issues is presented. Real mining tremor signals, registered in the vicinity of the objects were used in the numerical analyses. The correct determination of the dynamic resistance of the object can be used as a basis for performing repair/strengthening of existing objects, which in the future will be loaded with additional paraseismic influences.
An open source toolkit for 3D printed fluidics
Authors: Price Adam J. N. , Capel Andrew J. , Lee Robert J. , Pradel Patrick , Christie Steven D. R. 
Published: October 2020

AbstractAs 3D printing technologies become more accessible, chemists are beginning to design and develop their own bespoke printable devices particularly applied to the field of flow chemistry. Designing functional flow components can often be a lengthy and laborious process requiring complex 3D modelling and multiple design iterations. In this work, we present an easy to follow design workflow for minimising the complexity of this design optimization process. The workflow follows the development of a 3D printable ‘toolkit’ of common fittings and connectors required for constructing basic flow chemistry configurations. The toolkit components consist of male threaded nuts, junction connectors and a Luer adapter. The files have themselves been made freely available and open source. The low cost associated with the toolkit may encourage educators to incorporate flow chemistry practical work into their syllabus such that students may be introduced to the principles of flow chemistry earlier on in their education and furthermore, may develop an early appreciation of the benefits of 3D printing in scientific research. In addition to the printable toolkit, the use of the 3D modelling platform – Rhino3D has been demonstrated for its application in fluidic reactor chip design modification. The simple user interface of the programme reduces the complexity and workload involved in printable fluidic reactor design.
Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis
Authors: Marciniec Krzysztof , Beberok Artur , Pęcak Paweł , Boryczka Stanisław , Wrześniok Dorota 
Published: October 2020

Abstract
Background
A large body of research has focused on fluoroquinolones. It was shown that this class of synthetic antibiotics could possess antiviral activity as a broad range of anti-infective activities. Based on these findings, we have undertaken in silico molecular docking study to demonstrate, for the first time, the principle for the potential evidence pointing ciprofloxacin and moxifloxacin ability to interact with COVID-19 Main Protease.

Methods
In silico molecular docking and molecular dynamics techniques were applied to assess the potential for ciprofloxacin and moxifloxacin interaction with COVID-19 Main Protease (Mpro). Chloroquine and nelfinavir were used as positive controls.

Results
We revealed that the tested antibiotics exert strong capacity for binding to COVID-19 Main Protease (Mpro). According to the results obtained from the GOLD docking program, ciprofloxacin and moxifloxacin bind to the protein active site more strongly than the native ligand. When comparing with positive controls, a detailed analysis of the ligand–protein interactions shows that the tested fluoroquinolones exert a greater number of protein interactions than chloroquine and nelfinavir. Moreover, lower binding energy values obtained from KDEEP program were stated when compared to nelfinavir.

Conclusions
Here, we have demonstrated for the first time that ciprofloxacin and moxifloxacin may interact with COVID-19 Main Protease (Mpro).