bluuebunny/crossref_metadata_2025_split huggingface dataset:
PSICOLOGIA E A DESIGUALDADE SOCIAL NA EDUCAÇÃO SUPERIOR: AS ARTIMANHAS DE (RE)PRODUÇÕES SÓCIO-HISTÓRICAS
Authors: Gomes Lucélia Maria Lima da Silva , Oliveira Adélia Augusta Souto de 
Published: October 2020

A abordagem da permanência do estudante em situação de desigualdade social na educação superior associa-se às ações vinculadas aos programas para a redução dos índices de retenção e evasão. Essas ações se fundamentam no Programa Nacional de Assistência Estudantil e partem dos setores de assistência estudantil das Instituições Federais de Ensino Superior, que possuem em sua composição profissionais da área de Psicologia. Realizou-se uma pesquisa qualitativa, a partir dos pressupostos da Psicologia Sócio-histórica, de caráter documental, sobre as ações desenvolvidas pela Psicologia nos contextos da assistência estudantil no Nordeste brasileiro. Para tanto, analisou-se 23 documentos provenientes dos sites institucionais da assistência estudantil de nove instituições. Os resultados indicaram que a Psicologia na Assistência estudantil é direcionada para uma atenção à saúde do estudante; prevalece uma concepção clínica da Psicologia Escolar e Educacional; ações inovadoras são coletivas e perspectivam o desempenho acadêmico e desenvolvimento psicossocial nos diversos âmbitos da vivência universitária.
Palavras-chave: Psicologia escolar; desigualdade; assistência estudantil; atuação profissional
SUBJETIVAÇÃO POLÍTICA E AUMENTO DA POTÊNCIA DE AÇÃO: QUEM SÃO OS USUÁRIOS DOS CRAS?
Authors: Maheirie Kátia , Gomes Marcela de Andrade , Tonial Felipe , Minchoni Tatiana , Arndt Andressa Dias , Corrêa Bruna 
Published: October 2020

Este artigo é parte de uma pesquisa mais ampla, cujo objetivo geral foi identificar os discursos sobre as práticas de trabalho das equipes nos Centro de Referência em Assistência Social (CRAS) em diferentes municípios do Brasil, buscando problematizar os avanços no que se refere à promoção de experiências coletivas naquele contexto. Neste artigo, focamos no material de dois municípios da região sul do país, no que diz respeito a quem é o usuário na perspectiva dos trabalhadores da assistência social, por meio de entrevistas coletivas com cada equipe, em cada equipamento. A partir da psicologia sócio-histórica e das ideias de Jacques Rancière, analisamos os discursos, construímos cenas como material de pesquisa e com elas dialogamos categorias analíticas. Os resultados trouxeram duas categorias: a experiência da subjetivação política e a potência dos usuários da assistência social, apontando possibilidades para promoção da cidadania nos fazeres psicossociais.
Palavras-chave: subjetivação política; usuários da assistência social; identidade
EXPERIÊNCIA E (DES)IDENTIFICAÇÃO NO ENFRENTAMENTO DE DESIGUALDADES E PRECONCEITOS NA PERCEPÇÃO DOS AGENTES COMUNITÁRIOS DE SAÚDE
Authors: Machado Frederico Viana , Teixeira Luciana Barcellos , Possa Lisiane Boêr 
Published: October 2020

Este artigo discute tematizações sobre o preconceito no discurso de trabalhadores da saúde que cursaram o Projeto Caminhos do Cuidado, identificando efeitos que colaboraram para a superação destas relações com relação a usuários de álcool e outras drogas. Utilizamos metodologia qualitativa, com análise de conteúdo. A análise se baseou em dados provenientes de 78 rodas de conversa e 39 registros etnográficos, ocorridas nas 27 Unidades Federativas do Brasil. Os dados descrevem movimentos reflexivos dos trabalhadores que possibilitaram o enquadramento de relações identitárias para além de crivos morais e da essencialização dos sujeitos. Nossos resultados apontam a importância da experiência para a desconstrução de estereótipos e preconceitos, por produzir processos de desidentificação necessários para a superação de preconceitos. Destaca-se a importância do Agente Comunitário de Saúde, como o profissional estratégico para o trabalho com a temática do preconceito nos territórios.
Palavras-chave: Desigualdade; Preconceito; Atenção Básica; Intervenção Psicossocial; Agentes Comunitários de Saúde;
El «Llibre de les Bèsties» (1287-1289) de Ramon Llull: anàlisi d’adaptacions infantils i juvenils
Authors: Selfa Sastre Moisés , Falguera Garcia Enric 
Published: October 2020

En aquest article presentem una anàlisi de les 6 adaptacions que del Llibre de les Bèsties (1287-1289) es van publicar per al públic infantil i juvenil amb motiu de l’Any Llull (2015-2016). Després de presentar la figura de Ramon Llull com a escriptor de referència en l’època medieval i de situar el Llibre de les Bèsties dins de la producció literària de Llull, analitzem els paratextos extratextuals i textuals de les 6 adaptacions aquí estudiades. La presentació i anàlisi d’aquests paratextos ens permet determinar, d’una banda, a quin tipus de nivell lector va adreçada cada adaptació i quin treball didàctic en pot resultar; i, d’altra banda, com el missatge que Llull transmet en aquesta obra literària pot ser copsat pel públic infantil i juvenil del segle XXI.
Exploration of ovine milk whey proteome during postnatal development using an iTRAQ approach
Authors: Zhang Xueying , Li Fadi , Qin Fang , Li Wanhong , Yue Xiangpeng 
Published: October 2020

Background
Ovine milk is a rich source of bioactive proteins that supports the early growth and development of the newborn lambs. A large number of researches had targeted to the identification of ovine milk fat globule membrane proteins (MFGMPs), caseins (CNs), mastitis milk proteins in past years, but the dynamic change tendency of milk whey proteins during postnatal development has received limited attention. This research aimed to investigate the dynamic changes of ovine milk whey proteins after delivery, and explore the functions of whey proteins on early development of the newborns.

Methods
In this research, Hu sheep milk samples were collected from six individuals by manual milking manner, at 0 d, 3 d, 7 d, 14 d, 28 d and 56 d after delivery, respectively. The milk whey proteins were identified and quantified by the isobaric tag for relative and absolute quantification (iTRAQ) coupled with liquid chromatography (LC)-electrospray ionization (ESI) tandem MS (MS/MS) methods. In addition, biological functions of differentially expressed proteins (DEPs) were annotated by Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis.

Results
A total of 310 proteins were identified , of which 121 were differentially expressed. In detail, 30 (10 up-regulated and 20 down-regulated), 22 (11 up-regulated and 11 down-regulated), 11 (four up-regulated and seven down-regulated), 11 (eight up-regulated and three down-regulated), 10 (six up-regulated and four down-regulated) DEPs were identified in 3 d vs. 0 d, 7 d vs. 3 d, 14 d vs. 7 d, 28 d vs. 14 d, 56 d vs. 28 d comparison groups, respectively. The GO annotation analysis revealed that biological process principally involved metabolic and biological regulation, the major cellular location were organelle, cell and extracellular region, and the mainly molecular function were binding and catalytic activity. Circadian rhythm, fatty acid biosynthesis and African trypanosomiasis were enriched by KEGG annotation analysis.

Conclusion
The study reveals a comprehensive understanding of Hu sheep milk proteome, suggesting whey proteins change dramatically in early development of newborn lambs, which provide a potential guidance for early weaning of lambs.
Adequacy of clinical information in X-ray referrals for traumatic ankle injury with reference to the Ottawa Ankle Rules—a retrospective clinical audit
Authors: Gomes Yolanda E. , Chau Minh , Banwell Helen A. , Davies Josephine , Causby Ryan S. 
Published: October 2020

Study Objective
To assess the adequacy of clinical information with reference to the Ottawa Ankle Rules (OAR) in X-ray referrals for adults with traumatic ankle injury in the ED of a South Australian tertiary hospital and report upon referring trends between emergency department clinicians.

Methods
A retrospective clinical audit of adult ankle X-ray referrals in the emergency department was conducted. Eligible referrals were screened for their adherence to the OAR, patient details, clinical history and referrer. A logistic regression was used to determine the influence of these factors on the likelihood of being referred for X-rays despite not meeting the OAR criteria. Sensitivity, specificity, positive and negative likelihood ratios and their associated confidence intervals were calculated to assess the diagnostic accuracy of the OAR for those referred.

Results
Out of the 262 eligible referrals, 163 were deemed to have met the criteria for the OAR. Physiotherapists showed the highest OAR compliance of 77.3% and were the most accurate in their use of the rules, with a sensitivity of 0.86. Medical officers, registrars and interns were 2.5 times more likely to still refer a patient for X-ray if they did not meet the OAR criteria, compared to physiotherapists as the baseline. Patient age, duration of injury etc. were not significantly associated with likelihood of referral (even when they did not meet OAR criteria). The overall sensitivity, specificity, positive and negative likelihood ratios of the OAR were 0.59 (95% CI [0.47–0.71]), 0.37 (95% CI [0.30–0.44]), 0.93 (95% CI [0.76–1.16]) and 1.10 (95% CI [0.82–1.48]) respectively.

Conclusion
The results of this audit demonstrated poor sensitivity and moderate compliance by referrers with the rule. Reasonable evidence exists for the implementation of individual and/or institutional-based change strategies to improve clinician compliance and accuracy with use of the OAR.
A glitch in the matrix: Age‐dependent changes in the extracellular matrix facilitate common sites of metastasis
Authors: Marino Gloria E. , Weeraratna Ashani T. 
Published: October 2020

AbstractPeople over 55 years old represent the majority of cancer patients and suffer from increased metastatic burden compared to the younger patient population. As the aging population increases globally, it is prudent to understand how the intrinsic aging process contributes to cancer progression. As we age, we incur aberrant changes in the extracellular matrix (ECM) of our organs, which contribute to numerous pathologies, including cancer. Notably, the lung, liver, and bone represent the most common sites of distal metastasis for all cancer types. In this review, we describe how age‐dependent changes in the ECM of these organs influence cancer progression. Further, we outline how these alterations prime the premetastatic niche and why these may help explain the disparity in outcome for older cancer patients.
HLA‐B27 association of autoimmune encephalitis induced by PD‐L1 inhibitor
Authors: Chang Hyeyeon , Shin Yong‐Won , Keam Bhumsuk , Kim Miso , Im Seock‐Ah , Lee Soon‐Tae 
Published: October 2020

AbstractObjectiveWhile immune checkpoint inhibitors are increasingly used for various cancers, unpredictable immune‐related adverse events (irAEs) such as autoimmune encephalitis is life‐threatening. Here, we report an association between human leukocyte antigen (HLA) and atezolizumab‐induced encephalitis.MethodsFrom an institutional prospective cohort for encephalitis, we identified patients with autoimmune encephalitis after the use of atezolizumab, a PD‐L1 (programmed death‐ligand 1) inhibitor, from August 2016 to September 2019 and analyzed their HLA genotypes.ResultsA total of 290 patients received atezolizumab, and seven patients developed autoimmune encephalitis, and five of whom were enrolled for the analysis. The patients presented altered mentality, seizures, or myelitis. Three patients had the HLA‐B*27:05 genotype in common (60%), which is significantly frequent given its low frequency in the general population (2.5%). After Bonferroni correction, HLA‐B*27:05 was significantly associated with autoimmune encephalitis by atezolizumab (corrected P < 0.001, odds ratio 59, 95% CI = 9.0 ~ 386.9).InterpretationHere we found that three in five patients with autoimmune encephalitis associated with atezolizumab had the rare HLA‐B*27:05 genotype. Further systematic analyses in larger cohorts are necessary to investigate the value of HLA screening to prevent the life‐threatening adverse events.
Nanoscale Controlled Oxidation of Liquid Metals for Stretchable Electronics and Photonics
Authors: Martin‐Monier Louis , Gupta Tapajyoti Das , Yan Wei , Lacour Stéphanie , Sorin Fabien 
Published: October 2020

AbstractLiquid metals based on gallium have attracted considerable attention for soft and bioelectronics, thanks to their excellent combination of stretchability and conductivity. Nevertheless, owing to their large surface tension, these materials are notoriously difficult to pattern and shape into thin continuous films, or nanoscale 2D architectures, hindering practical use in systems with reduced dimensions. Herein, thanks to fine control in both substrate surface state and oxidation dynamics, a process for producing stretchable gallium‐based conducting films with percolation down to 90 nm thickness is presented. By further combining this process with lithography, it is also demonstrated that the approach enables, for the first time, stable stretchable gallium‐based optical metasurfaces with tunable resonance in the infrared. It is shown that oxygen partial pressure during evaporation determines the initial film percolation via an interplay between oxidation and dewetting. With this approach, conducting films with relative resistance change as low as 3% over 50% strain, with an excellent stability over 15k cycles are also demonstrated. Tunable soft optical metasurfaces with sub‐micrometer feature sizes are also realized, paving the way toward a novel paradigm in soft electronics and photonics.
Structured Interfaces for Improving the Tensile Strength and Toughness of Stiff/Highly Stretchable Polymer Hybrids
Authors: Wu Dong , Zhao Zeang , Wang Panding , Pei Yongmao , Chen Haosen , Qi H. Jerry , Fang Daining 
Published: October 2020

AbstractThe stiff/highly stretchable polymer hybrids have a broad field of applications including robotics, electronic devices, and biomedical devices. However, poor interfacial bonding between chemically dissimilar polymers makes it difficult to achieve reliable structural performance. Building a robust interface within the polymer hybrids is one of the most important concerns. Here, the structured interface with different geometrical waveform patterns, including zigzag, buzzsaw, and strip shape is investigated for their effectiveness in improving mechanical properties of the interface. The enhancement effects of different geometries of the structured interfaces on both the tensile strength and tensile toughness are characterized by uniaxial tension tests. The finite element analysis simulations of the interface are implemented to investigate the enhancement mechanism, considering both the material nonlinearity under large deformation and the geometric nonlinearity derived from the high asymmetry in the interfacial configuration. Both the interfacial geometry and the intrinsic adhesive property of materials influence the load transfer mechanism at the interface and consequently determine the failure modes. Optimal geometrical designs of the interfacial geometries are proposed to achieve the best interfacial enhancement. The present study may provide guidance for designing the interfacial geometries in the polymer hybrids.
Leukoencephalopathy with calcifications and cysts: Genetic and phenotypic spectrum
Authors: Crow Yanick J , Marshall Heather , Rice Gillian I , Seabra Luis , Jenkinson Emma M , Baranano Kristin , Battini Roberta , Berger Andrea , Blair Edward , Blauwblomme Thomas , Bolduc Francois , Boddaert Natalie , Buckard Johannes , Burnett Heather , Calvert Sophie , Caumes Roseline , Ng Andy Cheuk‐Him , Chiang Diana , Clifford David B , Cordelli Duccio M , de Burca Anna , Demic Natasha , Desguerre Isabelle , De Waele Liesbeth , Di Fonzo Alessio , Dunham S. Richard , Dyack Sarah , Elmslie Frances , Ferrand Mickaël , Fisher Gemma , Karimiani Ehsan Ghayoor , Ghoumid Jamal , Gibbon Frances , Goel Himanshu , Hilmarsen Hilde T , Hughes Imelda , Jacob Anu , Jones Elizabeth A , Kumar Ram , Leventer Richard J , MacDonald Shelley , Maroofian Reza , Mehta Sarju G , Metz Imke , Monfrini Edoardo , Neumann Daniela , Noetzel Michael , O'Driscoll Mary , Õunap Katrin , Panzer Axel , Parikh Sumit , Prabhakar Prab , Ramond Francis , Sandford Richard , Saneto Russell , Soh Calvin , Stutterd Chloe A , Subramanian Gopinath M , Talbot Kevin , Thomas Rhys H , Toro Camilo , Touraine Renaud , Wakeling Emma , Wassmer Evangeline , Whitney Andrea , Livingston John H , O'Keefe Raymond T , Badrock Andrew P 
Published: October 2020

AbstractBiallelic mutations in SNORD118, encoding the small nucleolar RNA U8, cause leukoencephalopathy with calcifications and cysts (LCC). Given the difficulty in interpreting the functional consequences of variants in nonprotein encoding genes, and the high allelic polymorphism across SNORD118 in controls, we set out to provide a description of the molecular pathology and clinical spectrum observed in a cohort of patients with LCC. We identified 64 affected individuals from 56 families. Age at presentation varied from 3 weeks to 67 years, with disease onset after age 40 years in eight patients. Ten patients had died. We recorded 44 distinct, likely pathogenic, variants in SNORD118. Fifty two of 56 probands were compound heterozygotes, with parental consanguinity reported in only three families. Forty nine of 56 probands were either heterozygous (46) or homozygous (three) for a mutation involving one of seven nucleotides that facilitate a novel intramolecular interaction between the 5′ end and 3′ extension of precursor‐U8. There was no obvious genotype–phenotype correlation to explain the marked variability in age at onset. Complementing recently published functional analyses in a zebrafish model, these data suggest that LCC most often occurs due to combinatorial severe and milder mutations, with the latter mostly affecting 3′ end processing of precursor‐U8.
Photoinduced Borylation Reactions: An Overview
Authors: Yadagiri B. , Daipule Komal , Singh Surya Prakash 
Published: October 2020

AbstractThe photochemical reactions perform a progressively important role in the field of green chemistry and organic synthesis from the last decades. It has always been considered as eco‐friendly, inexpensive, most abundant and endlessly renewable energy source. The organoboronic acids and esters occupy a central position in the field of chemistry so the development of novel methodology for the preparation of organoboron compounds is essential. In recent years, visible light‐induced photoredox catalysis has created a more influence on the preparation of different organoboron compounds using novel synthetic methodologies with very mild and eco‐friendly conditions. In this review, we have provided a brief overview of preparation of organoboronic acids or esters from aliphatic, aromatic C−H/C−X and other functional groups by photoredox methodology.
Study the synthesis and the properties of self‐crosslinking acrylic latex via a novel fluorescent labeling method
Authors: Qiu Zhenyu , Wang Lijun , Wu Jiming , Wang Lei , Li Zhaolei , Xu Zexiao , Li Weili , Gui Taijiang 
Published: October 2020

AbstractTo make waterborne painting be applied into metal protection area, the mechanical, water resistant, and anti‐corrosion properties of the dried coating based on it should be improved effectively. Among various methods, self‐crosslinking the latex during its drying process is thought to be an effective way. For example, the latex with DAAM/ADH (diacetoneacrylamide/adipoyl hydrazide) as the self‐crosslinker has attracted a lot of attention due to its excellent stability and coating performance. In this study, a kind of reactable AIEgen was used and taken part in synthesizing the self‐crosslinkable acrylic latex. Based on Aggregation Induced Emission(AIE) phenomenon, it is easy to real‐time trace the preparation and curing process of the obtained latexes. At the same time, the influence of DAAM/ADH on the properties of the cured coating was studied in detail. In addition, as AIEgen is knitted onto the polymer chains via chemical bonds, external stimulus might interfere the coating's fluorescent property. Based on this phenomenon, the cured coating was studied and explored the feasibility to be applied into gas sensing area via its fluorescent property.
Irradiation processing of immiscible PP/EOC blend: Morphology control and processability modification
Authors: Hassan Fatemeh , Entezam Mehdi 
Published: October 2020

AbstractIn this study, applying electron beam irradiation method at a relatively low‐irradiation dose (20 kGy) under the air atmosphere to prepare injectable polypropylene (PP)/ethylene‐octene copolymer (EOC) blends with fine morphology and appropriate performance was investigated. For this purpose, an extrusion PP grade with an EOC grade suitable to improve its impact resistance was melting blended. Gel content and rheological measurements revealed long‐chain branching is predominant phenomenon occurring during the irradiation process of EOC. Blend irradiation resulted in changing its melt flow index proper for injection molding. A fine morphology obtained for the unirradiated blend was preserved for the irradiated blend. Moreover, irradiation thermally stabilized the blend morphology. Blends linear viscoelastic behavior discussed by proper rheological models revealed the existence of interfacial interactions and a reduction of the interfacial tension between irradiated blend phases. No significant effect of irradiation on the crystallization characteristics of EOC and the blend was observed. The satisfying impact resistance of the irradiated blend was near to that of the unirradiated blend, although its tensile mechanical properties were less.
Synthesis and antimicrobial activity of new 2‐piperazin‐1‐yl‐N‐1,3‐thiazol‐2‐ylacetamides of cyclopenta[c]pyridines and pyrano[3,4‐c]pyridines
Authors: Sirakanyan Samvel , Kartsev Victor , Spinelli Domenico , Geronikaki Athina , Petrou Anthi , Ivanov Marija , Glamoclija Jasmina , Sokovic Marina , Hakobyan Elmira , Hovakimyan Anush 
Published: October 2020

AbstractIn this study, we report the synthesis and antimicrobial activity of some new disubstituted piperazines. Thus, 3‐chlorocyclopenta[c]pyridines and 6‐chloropyrano[3,4‐c]pyridine 1 under mild reaction conditions with piperazine gave the 3(6)‐piperazine‐substituted cyclopenta[c]pyridines and pyrano[3,4‐c]pyridine 2. Furthermore, the latter, by alkylation with 2‐chloro‐N‐1,3‐thiazol‐2‐ylacetamide, led to the formation of the target compounds. The evaluation of the antibacterial activity revealed that 3k was the most potent compound. The most sensitive bacterium was found to be Listeria monocytogenes, whereas Staphylococcus aureus was the most resistant one. Three compounds, 3d, 3g, and 3k, were tested also against the following resistant strains: methicillin‐resistant S. aureus (MRSA), Escherichia coli, and Pseudomonas aeruginosa. All three compounds appeared to be more potent than ampicillin against MRSA. Moreover, compound 3d showed a better activity than the reference drug ampicillin against P. aeruginosa, whereas 3g was more efficient against E. coli. The best antifungal activity was observed again for compound 3k. The most resistant fungi appeared to be Aspergillus fumigatus, whereas Trichoderma viride seemed the most sensitive one toward the compounds tested. Molecular docking studies on E. coli MurB, as well as on Candida albicans CYP51 and dihydrofolate reductase, were used for the prediction of the mechanisms of the antibacterial and antifungal activities, confirming the experimental results.