bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uvulopalatopharyngoplasty and barbed reposition pharyngoplasty with and without hyoid suspension for obstructive sleep apnea hypopnea syndrome: A comparison of long-term functional results
Authors: Antonio Minni  , Cialente Fabrizio , Ralli Massimo , Colizza Andrea , Lai Quirino , Placentino Angelo , Franco Melania , Rossetti Valeria , De Vincentiis Marco 
Published: April 2020

Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common condition; when conservative approaches are not effective, surgical techniques aimed at reducing the airway obstruction effect are used. This retrospective study aimed at comparing the functional outcomes in patients with OSAHS undergoing uvulopalatopharyngoplasty (UPPP) according to Fairbanks and barbed reposition pharyngoplasty (BRP) according to Mantovani, with or without hyoid suspension (HS). One-hundred twenty-two consecutive OSAHS patients who underwent surgical treatment were included in the study. Patients were divided into 4 groups; all patients underwent preoperative and postoperative polysomnography (PSG) with apnea/hypopnea index (AHI) and oxygen desaturation index (ODI) evaluation, and Epworth Sleepiness Scale (ESS) evaluation. The results were analyzed according to the different surgical procedures, in relation to the preoperative PSG and anthropometric data. A significant reduction was observed at 18-month follow-up for patients in BRP group for BMI (p = 0.004), ESS (p < 0.0001), ODI (p < 0.0001), and AHI (p < 0.0001). Risk factors for poor postoperative AHI reduction were evaluated; preoperative AHI was the strongest independent protective factor, while preoperative ODI was the strongest risk factor. The association of HS with UPPP or BRP showed significant results in terms of higher postoperative AHI reduction only when associated to UPPP (p < 0.0001). This study showed that the BRP technique was more effective compared to UPPP for patients with OSAHS. The association of HS showed greater benefits in UPPP compared to BRP. Randomized prospective trials with longer follow-up are necessary to confirm our results and formulate a more accurate indication of the optimal therapeutic strategy.
A retrospective study of maternal mortality in a tertiary care hospital in Western Maharashtra, India
Authors: Gaikwad Nandkishore B. , M. Poornima , Lad Reshma M. 
Published: April 2020

Background: Maternal mortality is a vital index of the effectiveness of obstetric services prevailing in a country. The key to progress of a country lies in reducing its maternal morbidity and mortality, hence to give a better assessment of the problem a retrospective study on maternal mortality was carried out. An objective of the study was to find the cause and epidemiological factors for maternal mortality in a tertiary care hospital in western Maharashtra from January 2018 to August 2019.Methods: A retrospective, descriptive study done at tertiary care hospital in western Maharashtra from January 2018 to august 2019. Data was collected from medical records department and the study was conducted by reviewing the records of maternal death and scrutinizing for various aspects likely to be related to maternal death such as age, locality of residence, antenatal care, admission death time interval and cause of death.Results: during the study period 63 maternal deaths occurred and 75302 live births, Maternal Mortality Ratio were 83.66 per 1 lakh live birth. 46% of maternal deaths were in age group of 21-25 years, 87% of patients belonged to rural area, 74% belonged to lower socioeconomic status. 43% were unregistered patients, 43% had vaginal delivery, 73% had no free transportation, 68% were referred patients, 60% were referred from private hospitals, 48% of maternal death occurred <24 hours, 73% of maternal death were due to direct cause, 28% of maternal deaths were due to pre-eclampsia and its complications, 15.8% due to sepsis and 12.6% due to Postpartum hemorrhage.Conclusions: Being a tertiary care hospital, where patients are referred from periphery maternal mortality was found to be on higher side. Proper implementation of government policies with community participation along with strengthening of First Referral Unit (FRU) and Primary Health Centres can help to reduce maternal mortality.
Post stroke psychiatric syndrome: a clinical study
Authors: Singh Amrendra K. , Raghuvanshi Gyanendra 
Published: April 2020

Background: Various psychiatric symptoms are seen after strokes which are usually deserted due to poor familiarity about it, hence better knowledge and understanding of various post stroke psychiatric manifestations may help in early identification and management of it. The aim of present research is to study the demographic and clinical profile of various post stroke psychiatric manifestations.Methods: The study was conducted on ninety patients developing psychiatric symptoms after stroke. Detailed socio-demographic characteristics, clinical profile along with psychiatric assessment were recorded in proforma specially designed for the study.Results: Bulk of this post- stroke psychiatric subjects (45%) was in the age range of 61-80 years of which male and female were 29% and 16% respectively. Most of patients (90%) were residing at rural areas. 47.8 % patients were belonging to lower middle socio-economic status. Majority of subjects (42.8%) were unemployed followed by farmer and skilled worker (20% each), and most of the patients were right handed (97.8%). On clinical parameters maximum subjects (52.2) developed post stroke major depression followed by depression mixed with anxiety (16.6%). Rest of patients suffered from organic anxiety disorder (8.8%), vascular dementia (10%), amnestic syndrome (5.5%), post stroke psychosis (3.3%), organic manic disorder (2.2%), pathological laughter and crying (1.1%).Conclusions: Huge number of patients (52.9%) developed psychiatric problems of diverse nature among patients with stroke syndrome. depression was most common post stroke psychiatric manifestation, followed by mixed anxiety with depression. Generally the post stroke psychiatric manifestations are unrecognized and untreated, which has adverse impact on process of stroke rehabilitation. Thus a detailed psychiatric evaluation is mandatory in all patients of stroke syndrome to rule out psychiatric illness.
SAMSUN’DA ÖĞRENCİLEŞTİRME SORUSU VE TOPLUMSAL ETKİLERİ
Authors: KIRMIZI Meriç , GÜROL Neval , YILDIZ Havvanur 
Published: April 2020

Bu çalışmada “öğrencileştirme” kavramıyla Samsun Atakum’daki Körfez Mahallesi’nin değişimi
incelenmiştir. Kentin üniversite bölgesi olan Körfez Mahallesi’nde Ekim 2018-Mayıs 2019 arasında,
küçük dairelerde kalan dokuz öğrenci, üç emlakçı, iki esnaf ve bir muhtarı kapsayan, toplam 15 kişiyle
görüşülmüştür. Mahalle buradaki tütün tarlalarının el değiştirip, yapılaşmaya açılması ve bu tarlalarda
çalışanların yerinden edilmesiyle değişmeye başlamıştır. Bu kentleşmenin sonucunda mahalle nüfusu
öğrenciler, genç profesyoneller, sayıca az da olsa, aileler ve kırsal kökenli, eski yaşayanlar olarak
ayrışmıştır. Körfez Mahallesi’nde eski ve yeni yerleşim yeri olarak ikili bir yapılaşma görülmektedir;
deniz kıyısına yakın, yeni yerleşimler öğrencilere yönelik konut alanlarıdır. Mahallede üretilen konut
türleri öğrenci beklentilerine göre zamanla değişmiş ve küçülmüştür. Üretilen konutların değerlenmesi
burada bir “rant farkı”nın oluştuğunu göstermektedir. Konut alanındaki gelişme “yeni yapı yoluyla
soylulaştırma”yla ilişkilendirilebilirken, mahalledeki ticari olanaklar aynı hızda gelişmemiştir. Çalışma
Körfez Mahallesi’nin bugünkü fiziksel ve toplumsal yapısını öğrencilerin etkisiyle yaşanan değişim
bağlamında çözümlemesi nedeniyle önemlidir.
THE EFFECTIVENESS OF GAME-BASED LEARNING MODEL IN THE JAVANESE LANGUAGE CLASS
Authors: Sukoyo Joko , Nurhayati Endang , Dwijonagoro Suwarna 
Published: April 2020

Purpose of the study: the objective of this study was twofold. Firstly, it aimed to examine the effectiveness of game-based learning in the Javanese language class for junior high school students. Secondly, it was intended to investigate the responses of the students upon completing the class that incorporated the game-based learning.
Methodology: This experimental research employed the post-test only control design. The data were collected from documentation, questionnaires, and evaluation tests. Further, the data were examined using a t-test.
Main Findings: The game-based model is effective for the Javanese language class. The average score test of the students taught by game-based learning reached 72.6. On the other hand, those participated in a class with different treatment scored 64.5 on average. Such a difference was significant, given the output of the independent sample T-test, which was from the result of analysis using the SPSS software.
Applications of this study: This study was beneficial to change the paradigm of the old-fashioned, boring Javanese teaching and learning. It promoted the idea of fun teaching and learning. On top of that, the implementation of the learning model was effective to enhance students’ The Javanese language skills, specifically in Central Java, East Java, and the Special Region of Yogyakarta.
Novelty/Originality of this study: Learning models for local content subjects, such as the Javanese language, were still limited since the topic did not attract the attention of many researchers. Testing the game-based learning was among the alternatives of interesting learning methods to stimulate students to learn their local language, and thus, preserve the language in society.
POTENCIAL TURÍSTICO DA COMUNIDADE DIOGO LOPES EM RESERVA DE DESENVOLVIMENTO SUSTENTÁVEL ESTADUAL PONTA DO TUBARÃO - RDSEPT/RN
Authors: Da Silva Fernanda Martins , Gomes-Ferreira Ana Beatriz , Cesar Pedro Henrique , Moreira Sueli Aparecida 
Published: April 2020

O Turismo de base comunitária é uma alternativa no contexto do turismo sustentável que vem crescendo muito. Esse segmento de turismo tem um papel importante para a comunidade local, ao ajudar na conservação, no desenvolvimento regional, ao movimentar a economia da comunidade. A comunidade de Diogo Lopes, distrito de Macau, está inserida dentro da Reserva de Desenvolvimento Sustentável Estadual Ponta do Tubarão. A RDSEPT está localizada no litoral norte do Rio Grande do Norte, passou a ser reserva com a criação da lei estadual 8.349 de 17 de julho de 2003. O objetivo da pesquisa foi verificar a percepção dos moradores sobre a sustentabilidade na RDS. Portanto, realizou-se um estudo de natureza qualitativa, cuja abordagem se deu através da proposta de estudo da comunidade, utilizando-se um roteiro de entrevista com atores chaves da Reserva. Quanto aos resultados constatou-se, que a atividade turística na reserva é insipiente, mas o turismo é uma atividade viável para a RDS. Os pescadores apontaram deficiência na infraestrutura local e falta de apoio de lideranças políticas e do conselho gestor na reinvindicação de melhorias para a comunidade.
Sosialisasi dampak pernikahan dini terhadap kesehatan reproduksi Desa Sembung Kecamatan narmada Kabupaten Lombok Barat
Authors: Astuti Alfira Mulya 
Published: April 2020

[Bahasa]: Pernikahan dini memiliki dampak yang cukup berbahaya bagi yang melakukannya baik pria ataupun bagi wanita, dan dalam berbagai aspek seperti kesehatan, psikologi, dan mental. Walaupun pernikahan usia dini ini memiliki dampak positif, namun dibandingkan dengan faktor negatifnya tentu sangat tidak seimbang. Tersebut merupakan alasan sehingga dilakukannya pengabdian masyarakat di desa Sembung. Adapun fokus pengabdian ini adalah Sosialisasi mengenai dampak pernikahan dini di Desa Sembung Kecamatan Narmada Kabupaten Lombok Barat dengan menghadirkan narasumber dari Pihak Badan Koordinasi Keluarga Berencana Nasional Kota Mataram. Diawali dengan Sosialisasi mengenai dampak dari pernikahan dini dengan menghadirkan narasumber dari Pusat Studi Gender dan Anak, Bidan yang ditugaskan di Desa Sembung serta salah satu narasumber dari Badan Koordinasi Keluarga Berencana (BKKBN) Kota Mataram. Melakukan pembinaan bagi kaum wanita yang memiliki keterbatasan perekonomian untuk menciptakan suatu yang bermanfaat. Kesimpulan dari kegiatan ini adalah; pernikahan dini hukumnya sunah bagi yang dapat mengendalikan diri, dan akan menjadi wajib jika antara keduanya sudah tidak dapat mengendalikan dini, menikah dini dalam dua keadaan tersebut bisa mensyaratkan adanya kesiapan ilmu, harta (nafkah) dan fisik, disamping mensyaratkan tetap adanya kemampuan melaksanakan kewajiban menuntut ilmu, islam telah menetapkan hukum – hukum preventif agar para pemuda dan pemudi terhindar dari rangsangan dan godaan untuk berbuat maksiyat seperti zina, Keempat, bahwasanya pernikahan dini itu memiliki dampak positif dan negatif bagi yang melaksanakan, baik ditinjau dari fisik maupun psikisnya.
Kata Kunci: sosialisasi, dampak menikah dini, kesehatan reproduksi
THE BOARD OF THE NEW CODE OF THE INDIES (1776-1820): OBSERVATIONS AND CLARIFICATIONS FOR A REVISED INTERPRETATION
Authors: Vallejo García-Hevia José María 
Published: April 2020

The study of the formation and the analysis of the content of the well-known New Code of Laws of the Indies, approved, sanctioned and promulgated by Carlos IV of Spain in 1792, but not wholly and generally published, permits new conclusions and arenewed historiographical interpretation about its origin, development and the reasons behind the secrecy of it being in force, with the exception of twelve of its laws, ordered to be applied by the by governmental and judicial authorities of the Indiesbetween 1789 and 1804.
Academic-Service Partnership programs in nursing: Development and Psychometric Evaluation of Achieving Mutual Benefits Scale (AMBS)
Authors: Sadeghnezhad Maliheh , Nabavi Fatemeh Heshmati , Najafi Fereshteh , Kareshki Hossein , Esmaily Habibollah 
Published: April 2020

Abstract
Background: The first step for the establishment of academic-service partnership programs is identification of mutual benefits. The rate of achievement of these benefits reflects the success rate of the partnership program. This study aimed to develop an achieving mutual benefits scale in nursing academic-service partnership programs. Method: The AMBS was developed based on an analysis of the concept of mutual benefits in nursing academic-service partnership programs by the hybrid model approach. Findings of the concept analysis study was used to produce items pool. Then, the psychometric properties of the scale were evaluated using face, content and construct validities, and internal consistency, and stability for reliability. Results: The AMBS consists of 44 items. Exploratory factors analysis supported six factor with an explained variance of 59.06%. The Cronbach’s α, and Omega coefficient of the scale respectively ranged from 0.77 to 0.93, and 0.75 to 0.9. The content validity index of 0.97, and internal consistency of 0.76 were obtained for the final scale. Conclusions: The AMBS is a valid and reliable scale for the measurement of the mutual benefits achievement rate in nursing academic-service partnership programs in six dimensions of research synergy, managers' synergy in the student education, development of nursing services, reducing the theory-practice gap, and access to the supportive learning environment. It is necessary to consider all dimensions in organizing these programs and assessing the success rate of them.
Uptake of Misoprostol among women seeking abortion in Accra, Ghana
Authors: Darteh Eugene Kofuor Maafo 
Published: April 2020

Abstract
Background: Unsafe abortions remain one of the key contributors to maternal mortality. The WHO has recommended misoprostol as a safe abortifacient which has become a popular over the counter self-administered abortifacient in Ghana. This study sought to examine the prevalence of misoprostol uptake and model the factors associated with its uptake among 698 women seeking abortion services in the Accra Metropolis. Methods : Univariate and multivariate analysis were done. The multivariate analysis was done using binary logistic regression to model the factors associated with misoprostol uptake and results are presented as adjusted odds ratios (AORs) with their 95% confidence intervals (CIs). P < 0.05 was considered statistically significant.Results : The results showed that the prevalence of misoprostol uptake was 20.8%. The regression analysis showed that women aged 25-34 had 0.60 lower odds of using misoprostol compared with those aged 15-24 years [OR=0.60, CI=0.38-0.94]. Those who can save some money had higher odds [OR=2.31, CI=1.03-5.16] of using misoprostol compared with those who often do not have sufficient food. Those who were cohabiting/separated had higher odds [OR=1.83, CI=1.09-3.06] of using misoprostol compared to those who were never married. Those who had 1 [OR=0.26, CI=0.14-0.46] and 2 or more [OR=0.23, CI=0.07-0.76] had lower odds of using misoprostol compared to those who have never had a miscarriage. Conclusion : The prevalence of misoprostol uptake among women seeking abortion services in Accra Metropolis is relatively high. Age, socio-economic status, marital status and previous history of miscarriage are associated with misoprostol uptake. Although proven effective by various studies and recommended by the WHO, it is imperative to consider these factors in the education of women on the use of misoprostol as well as designing programmes to target women who are inclined to induce abortion in Ghana.
Comprehensive Analysis of Potential Key Genes in Progression of Large Cell Neuroendocrine Lung Carcinoma
Authors: Zhu Lihuan , Lin Zhaoxian , Chen Wenshu , Guo Tianxing , Ye Mingfan , Pan Xiaojie 
Published: April 2020

Abstract
Background

Pulmonary LCNEC (large-cell neuroendocrine carcinoma) is a kind of high-grade lung neuroendocrine tumors (NET). There’s an increase in the pathologically diagnosis of LCNECs during recent years. However, the underlying mechanisms of the progression of LCNEC still remains unclear.
Methods

In this article, we utilized three GEO datasets to elucidate the significant candidate genes and pathways in LCNEC: GSE1037, GSE11969, and GSE44447,including 17 LCNEC samples and 31 normal lung tissues, were analyzed using several bioinformatics methods to explore the key genes involved in the development of LCNEC. We identified ten hub genes which might be important in the pathogenesis of LCNEC. Then we performed western blot on specimens from four patients diagnosed with LCNEC in our hospital to validate these genes.
Results

Results showed that three genes (CCT4, CDC20, KNTC1) expressed highly in LCNEC.
Conclusion

The results of our study might provide new insights for the development of new biomarkers and therapeutic targets of LCNEC.
Experimental study on Leachate movement control and treatment using High Density Poly Ethylene (HDPE) Sheets
Authors: TPA Aravind , K Pranesh K , B Parameshwaran 
Published: April 2020

Abstract
Nowadays, in India, the incidents such as fire, groundwater contamination and emission of methane due to the open dumping of municipal solid wastes have become very common. To overcome these issues and also to reduce the foul smell emanating from the yards due to rain drenching the piles of accumulated wastes, sanitary landfills with proper leachate movement control facilities and recycling of leachates should be adapted. When landfill squanders (Municipal solid waste) debases and downpour washes through the solid wastes, the leachate is formed. The Leachate is a dark fluid containing organic and inorganic chemicals, heavy metals and pathogens. Leachate may permeate through the landfill liners and subsoil, causing contamination of surface water and sub - surface waters, which results to several health hazards. The synthesis of waste changes drastically over the life of the landfill because of the presence of organic and inorganic substances. This paper focuses towards the control of leachate movement in a sanitary landfill and partial treatment of leachate using HDPE (High Density Poly Ethylene) sheets, such that the partially treated leachate meets the standards prescribed for the quality of Irrigation water. In this paper, the characteristics of leachate were studied by filtering it through 1, 2 and 3 layers of HDPE sheets respectively. When analyzed, the characteristics of leachate such as pH, Turbidity, BOD, COD, TSS and TDS shows that the leachate collected from 3 layered HDPE filtration system has better quality than the other two systems and it could be used for irrigation purposes as a tool to ensure sustainability by contributing towards the reduction of water scarcity issue.
The Impact of COVID-19 on Gastric Cancer Surgery: A Single-center Retrospective Study Based on Real-world Data
Authors: Li Yu-xuan , He Chang-zheng , Liu Yi-chen , Zhao Peng-yue , Xu Xiao-lei , Wang Yu-feng , Xia Shao-you , Du Xiao-hui 
Published: April 2020

Abstract
Background ： A respiratory epidemic defined as coronavirus disease 2019 ( COVID-19 ) is becoming unstoppable and has been declared a pandemic. Patients with cancer are more likely to develop COVID-19. Based on our experience during the pandemic period, we propose some surgery strategies for gastric cancer patients under the COVID-19 situation.
Methods ： We defined the ‘COVID-19’ period as occurring between 2020-01-20 and 2020-03-20. All the enrolled patients were divided into two groups, pre-COVID-19 group (PCG) and COVID-19 group (CG). A total of 109 patients with gastric cancer were enrolled in this study.
Results ： The waiting times before admission increased by 4 days in CG(PCG:4.5 [IQR: 2, 7.8] vs. CG:8.0 [IQR: 2,20]; P = 0.006). More patients had performed chest CT scan besides abdominal CT before admission during COVID-19 period(PCG:22[32%]vs. CG:30[73%], p=0.001). After admission, during COVID period, the waiting time before surgery was longer(3[IQR: 2,5] vs. 7[IQR: 5,9]; P < 0.001),more laparoscopic surgery were performed(PCG: 51[75%] vs. CG: 38[92%],p=0.021), and hospital stay after surgery was longer (7[IQR: 6,8] vs.9[IQR:7,11] ; P < 0.001). The total cost of hospitalization increased during COVID period, (9.22[IQR:7.82,10.97] vs. 10.42[IQR:8.99,12.57]; p=0.006).
Conclusion ： Since no data is available yet on the impact of COVID-19 on gastric cancer patients,our own experience with COVID-19 in gastric cancer surgery has hopefully provided an opportunity for colleagues to reflect on their own service and any contingency plans they have to tackle the crisis.
Keywords: gastric cancer; coronavirus disease 2019; COVID-19; retrospective analysis; real-world data.