bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Perilaku Sedentary dengan Indeks Massa Tubuh dan Tekanan Darah serta Denyut Jantung pada Pegawai Struktural dan Administrasi RSUD Provinsi Sulawesi Utara
Authors: Walukouw Caesario S. J. , Lampah Christopher , Gessal Joudy 
Published: April 2020

Abstract: Due to high technology, sedentary behavior develops worldwide. Some conse-quences that might arise due to sedentary behavior inter alia increases in body mass index, blood pressure, and heart rate. The prevalences of obesity and high blood pressure in North Sulawesi are the highest ones in Indonesia. This study was aimed to identify the relationship between sedentary behavior and body mass index (BMI), blood pressure as well as heart rate among structural and administrative employees of North Sulawesi Regional Hospital as subjects. This was an analytical and observational study with a cross sectional design. Direct observation was performed on all subjects. The results showed that there were 37 employees as subjects. There was a strong correlation between sedentary behavior and blood pressure (r=0.684); a negative and very weak correlation between sedentary behavior and BMI (r=-0.101); and a very strong correlation between sedentary behavior and heart rate (r=0.796). In conclusion, there were relationships between sedentary behavior and blood pressure as well as heart rate. Albeit, there was no relationship between sedentary behavior and body mass indexKeywords: sedentary behavior, body mass index, blood pressure, heart rate Abstrak: Dengan kemajuan teknologi maka perilaku sedentary makin meningkat di seluruh dunia. Beberapa akibat yang dapat terjadi akibat perilaku sedentary ialah meningkatnya indeks massa tubuh (IMT), tekanan darah, dan denyut jantung. Prevalensi obesitas dan tekanan darah tinggi di Sulawesi Utara ialah yang tertinggi di seluruh Indonesia. Penelitian ini bertujuan untuk mengetahui hubungan antara perilaku sedentary dengan IMT, tekanan darah, serta denyut jantung pada pegawai struktural dan administrasi RSUD Provinsi Sulawesi Utara. Jenis penelitian ialah analitik observasional dengan desain potong lintang. Pada penelitian ini dilakukan pengamatan langsung terhadap subyek penelitian yaitu pegawai struktural dan administrasi RSUD Provinsi Sulawesi Utara yang memenuhi kriteria inklusi. Hasil penelitian mendapatkan korelasi kuat antara perilaku sedentary dengan tekanan darah (r=0,684); korelasi negatif yang sangat lemah antara perilaku sedentary dengan IMT (r=-0,101); dan korelasi sangat kuat antara perilaku sedentary dengan denyut jantung (r=0,796). Simpulan penelitian ini ialah terdapat hubungan antara perilaku sedentary dengan tekanan darah dan denyut jantung tetapi tidak terdapat hubungan antara perilaku sedentary dan indeks massa tubuhKata kunci: perilaku sedentary, indeks massa tubuh, tekanan darah, denyut jantung
Teori Belajar Kognitif Dan Implementasi Dalam Proses Pembelajaran
Authors: Wisman Yossita 
Published: April 2020

Pendidikan merupakan suatu usaha sadar yang dilakukan dengan cara membimbing, mengajar dan melatih peserta didik yang dapat menimbulkan perubahan dalam diri peserta didik dengan tujuan agar dapat tercapai kesesuaian anatara diri peserta didik dengan lingkungannya. Teori yang melandasi pendidikan pada dasarnya dibagi teoriasosiasi yang berorientasi induktif artinya bangunanilmu dalam pengembangan pendidikan didasarkan atas unit-unit pengetahuan,sikap dan keterampilan menjadi unit yang lebih universal ,aliran dalam teori ini adalah aliran behaviourisme atau lebih dikenal dengan aliran stimulus-respon. Aliran yang beranggapan bahwa pendidikan diarahkan pada terciptanya perilaku-perilaku baru pada peserta didik . Belajar merupakan salah satu bagian penting yang tidak dapat dipisahkan dengan proses pendidikan. Belajar merupakan proses perubahan perilaku dan pola pikir yang dialami oleh individu. Teori belajar kognitif menekankan bahwa yang terpenting dalam proses pendidikan adalah bagaimana proses tersebut terjadi daripada hasil yang dicapai.
THE FAST-CALLING SHORT-TAILED CRICKET ANUROGRYLLUS CELERINICTUS WALKER, 1973 (ORTHOPTERA: GRYLLIDAE) OCCURS IN CUBA, GREATER ANTILLES
Authors: Yong Sheyla 
Published: April 2020

This article gives a record of the Fast-calling Short-tailed Cricket Anurogryllus celerinictus Walker, 1973 in Cuba.
HOW NOT TO CONDUCT A SCIENTIFIC DEBATE: A COUNTERPOINT TO THE RECENT CRITIQUE OF THE “PRAGMATIC CLASSIFICATION” OF JUMPING SPIDERS (ARTHROPODA: ARACHNIDA: ARANEAE: SALTICIDAE)
Authors: Breitling Rainer 
Published: April 2020

The paper gives a counterpoint to the recent critique of the “pragmatic classification” of jumping spiders (Arthropoda: Arachnida: Araneae: Salticidae).
Memahami Tantangan Teologi Pluralisme dan Teologi Pembebasan
Authors: Paembonan Yafet M 
Published: April 2020

The diversity of religious beliefs in today's society has the potential to cause conflict, that is if each group insists on the truth it believes. Theology of pluralism is presently offering a new religion based on all the truths that are recognized. But is theology pluralism really the answer, or does it have a greater negative impact? At first glance, the emergence of a theology of pluralism is similar to the emergence of liberation theology as an attempt to answer theological problems. So in this study, the relationship between pluralism theology and liberation theology is discussed, as well as the impact of plural theology. Researchers conduct literature studies to examine the theology of pluralism, make comparisons, and ultimately draw conclusions. From this research, it can be concluded that there is a relationship between plural theology and liberation theology and that pluralism theology impacts relativism in standards, so there is no absolute moral standard. Abstrak: Keberagaman keyakinan agama di kalangan masyarakat masa kini berpotensi menimbulkan konflik, yaitu apabila masing-masing kelompok bersikukuh pada kebenaran yang diyakininya. Teologi pluralisme hadir menawarkan sebuah agama baru yang bertolak dari semua kebenaran yang diakui. Namun apakah teologi pluralisme sungguh-sungguh menjadi jawaban, ataukah justru memiliki dampak negatif yang lebih besar? Sekilas, kemunculan teologi pluralisme mirip dengan kemunculan teologi pembebasan sebagai sebuah upaya menjawab masalah teologis. Maka dalam penelitian ini dibahas hubungan antara teologi pluralisme dan teologi pembebasan, serta dampak dari teologi pluralisme. Peneliti melakukan studi pustaka untuk mencermati teologi pluralisme, melakukan komparasi, dan pada akhirnya menarik kesimpulan. Dari penelitian ini disimpulkan bahwa ada hubungan antara teologi pluralisme dan teologi pembebasan, dan bahwa teologi pluralisme berdampak pada relativisme dalam standar, sehingga tidak ada standar moral yang absolut.
A Content Analysis of the Journal of Band Research: 1964–2016
Authors: Hudson Michael W. , Silveira Jason M. 
Published: April 2020

Abstract
The purpose of this study was to conduct a content analysis of the Journal of Band Research since its inception in 1964 through 2016, a 52-year period. Scholarly articles (N = 503) were reviewed and independently coded to determine the type of methodology used in research, topic of the article, and author eminence within the journal. The coding procedure resulted in the creation of 12 separate methodological categories and 25 primary topics. Historical articles, analysis of repertoire, and descriptive studies were the most frequently represented methodologies, representing 82% of the sample. Articles examining 1 specific piece of literature, articles investigating band ensembles (e.g., Civil War bands, community bands, etc.), and biographies were the most frequently researched topics, representing 57% of the sample. Author eminence was determined by frequency of publication by contributing author and through citation tracking. J. C. Mitchell was the most frequently published author in the sample, and “Performance Evaluation Reliability at Selected Concert Festivals” (Burnsed, Hinkle, & King, 1985) was the most cited article in the sample (89 citations).
Genetic Diversity Based on Morphological Traits of 19 Maize Genotypes Using Principal Component Analysis and GT Biplot
Authors: Al-Naggar A. M. M. , Shafik M. M. , Musa R. Y. M. 
Published: April 2020

Among the phenotypic, biochemical, and molecular methods employed in assessment of genetic diversity, the phenotypic method has proven efficient for the assessment, description and classification of germplasm collections to enhance their use in maize breeding. The objectives of the present study were: (i) to assess the extent of genetic diversity in a collection of Egyptian commercial maize hybrids and populations, through field evaluation under water and N stressed and non-stressed conditions, using morphological data based on Principle Component Analysis (PCA), (ii) to measure the genetic distance among these genotypes using UPGMA cluster analysis and (iii) to assess the relationship between grain yield and yield-related traits of maize genotypes using GT-biplot analysis. A two-year field experiment was conducted in a split-split plot design with 3 replications, where 2 irrigation regimes, three N rates and 19 maize genotypes occupied the main plots, sub plots and sub-sub plots, respectively. The germplasm was assessed for 21 agronomic traits. Highly significant differences (P ≤ 0.01) were observed among the maize hybrids and populations for all measured traits. Results of the GT biplot in the present study indicated that high values of 100-Kernel weight, ears/plant, kernels/plant, kernels/row, plant height, nitrogen use efficiency, nitrogen utilization efficiency, and grain nitrogen content and short ASI could be considered reliable secondary traits for improving grain yield under stressed and non-stressed conditions. The highest genetic distance was found between G9 (SC-2055) and each of G15 (American Early Dent), G18 (Midland) or G19 (Ried Type). The Agglomerative Hierarchical Clustering based on phenotypic data assigned the maize genotypes into five groups. The different groups obtained can be useful for deriving the inbred lines with diverse features and diversifying the heterotic pools.
Bioprospecting of an Indigeneous Bacillus thuringiensis Strain G5-8-3T02 for Shrimp Culture System
Authors: Ariole Caroline Nchedo , Agulanna Euphemia Uchechi 
Published: April 2020

Aim: An indigenous Bacillus thuringiensis strain G5-8-3T02 earlier isolated from healthy shrimp intestine and established to safeguard Penaeus monodon from Vibrio mimicus infection was assessed as a potential candidate bacterium for drug enhancement for shrimp culture systems.
Methodology: Optimal temperature, pH and salinity for growth and antibacterial activity of Bacillus thuringiensis against Vibrio mimicus were determined. The effects of enzymes (pepsin, catalase, lipase and α- amylase), pH (2-9), heat (37°C – 121°C) and surfactants (Sodium dodecyl sulphate and Tween 80) on antibacterial activity were also evaluated. Cell growth and antibacterial activity were monitored daily for 5 days via spectrophotometric method at 600 nm and agar well diffusion assay respectively. The metabolite extracted with methanol was analyzed for bioactive compounds using Gas Chromatography-Mass Spectrometry (GC-MS).
Results: The optimum temperature, pH and salinity for growth and metabolite production were 35°C, pH 6-7 and 10-15 ppt. respectively. The crude extract did not totally lose its activity when treated with enzymes, various pH values, heat and surfactants. The quantitative composition of the metabolite revealed 15 bioactive compounds. The main compound produced was 2, 6, 10-Trimethyltridecane with peak area of 14.58%.
Conclusion: The non-pathogenic, antagonistic, indigenous Bacillus thuringiensis strain G5-8-3T02 could be engaged in the management of vibriosis in shrimp culture since the use of antibiotics in aquaculture for disease control yields objectionable effects. The identified bioactive compounds might be valuable for drug development for shrimp culture system.
A Copper‐Catalyzed Sonogashira Coupling Reaction of Diverse Activated Alkyl Halides with Terminal Alkynes Under Ambient Conditions
Authors: Cao Yu‐Xi , Dong Xiao‐Yang , Yang Jun , Jiang Sheng‐Peng , Zhou Shuangliu , Li Zhong‐Liang , Chen Guo‐Qiang , Liu Xin‐Yuan 
Published: April 2020

AbstractWe describe a copper‐catalyzed Sonogashira coupling reaction of alkyl halides with terminal alkynes under ambient conditions, efficiently providing a versatile tool for the construction of substituted alkynes. A new proline‐based N,N,P‐ligand is utilized to promote the transformation under a mild reaction condition. Diverse alkyl halides, such as primary and secondary (hetero)benzyl chlorides and bromides, secondary and tertiary α‐bromo amides and propargylic bromide, are applicable to provide a wide array of alkynes.magnified image
A flexible design framework for process systems under demand‐side management
Authors: Liu Yu , Fan Yueyue , Palazoglu Ahmet , El‐Farra Nael H. 
Published: April 2020

AbstractDemand response (DR) has been an appealing strategy for both residential and commercial/industrial customers of electricity due to the increasing penetration of renewable energy resources into the power grid and the deregulation of the energy markets. For industrial DR participants, the management of energy consumption along with the satisfaction of production expectations is generally referred to as demand‐side management. Recent research in this area has focused mostly on process scheduling and capacity planning, especially for energy‐intensive processes. This article presents a new direction through an optimization‐based process design paradigm that allows for the potential reconfiguration of the process flow sheet in real time. Based on a case study of pump network design, a network superstructure is first defined, followed by a two‐stage stochastic optimization model. The method of progressive hedging is used to solve the resulting mixed‐integer stochastic programming problem. The results demonstrate that, under various scenarios, the reconfigurable design offers significant benefits compared to a fixed network structure in terms of total design cost and expected operating cost.
Evidence for newly discovered albino mutants in a pyroloid: implication for the nutritional mode in the genus Pyrola
Authors: Shutoh Kohtaroh , Tajima Yuko , Matsubayashi Jun , Tayasu Ichiro , Kato Syou , Shiga Takashi , Suetsugu Kenji 
Published: April 2020

PremiseDifficulties in comparing extremely divergent features in fully mycoheterotrophic plants with those in closely related chlorophyllous plants have complicated attempts to reveal the evolutionary patterns and processes of fully mycoheterotrophic plants. Albino mutants of partially mycoheterotrophic plants, generally observed in Orchidaceae, have provided an ideal model for investigating the evolution of mycoheterotrophy within similar genetic backgrounds. In 2018, we found a putative albino population of Pyrola (Ericaceae). Here we aimed to reveal the identity of the albino pyroloid and confirm its fully mycoheterotrophic status.MethodsTo reveal the putative albino pyroloid's identity, we examined its morphology and sequenced its chloroplast DNA. In addition, we assessed the trophic status of the putative albino pyroloid by analyzing chlorophyll fluorescence, chlorophyll concentration, and natural 13C and 15N abundances.ResultsWe identified albino individuals as P. japonica—otherwise a partially mycoheterotrophic species. We confirmed their albino status by their considerably lower chlorophyll fluorescence and concentrations than those of sympatrically occurring chlorophyllous plants. 13C abundance in the albino individuals was significantly higher than in the green individuals of P. japonica.ConclusionsThis first report of albino mutants from partially mycoheterotrophic species in angiosperms other than orchids will play a valuable role in further studies focused on mycoheterotrophy. For instance, their δ13C and δ15N values represent a reference for fully mycoheterotrophic plants in Pyrola. Our findings also indicate the strong dependence of some leafy Pyrola species on fungal C during their entire life cycle.
A polyvinyl alcohol‐based mixed matrix membrane with uniformly distributed Schiff base network‐1 for ethanol dehydration
Authors: Wang Zhanbin , Liu Jiahao , Shan Houchao , Li Guozhen , Wang Ze , Si Zhihao , Cai Di , Qin Peiyong 
Published: April 2020

AbstractIn this study, Schiff base network (SNW)‐1 nanoparticles with high hydrophilicity and large specific surface area were used to prepare polyvinyl alcohol (PVA)‐based mixed matrix membranes (MMMs), which were evaluated for ethanol dehydration. Because of the low difference of density between SNW‐1 and PVA, the as‐prepared nanoparticles can be uniformly distributed into the PVA active layer. The effects of SNW‐1 loading, feed temperature, and water concentration on pervaporation (PV) performance were further studied. The results showed the MMM with 10 wt% of SNW‐1 loading exhibited a separation factor of 1,501 and a permeation flux of 187 g m−2h−1for feeding 95 wt% ethanol/water binary solution at 75°C. Overall, the SNW‐1/PVA MMMs showed great prospect in ethanol dehydration via PV.
Novel chyme reinfusion device for gastrointestinal fistulas and stomas: feasibility study
Authors: Sharma P , Davidson R , Davidson J , Keane C , Liu C , Ritchie S R , Chu K , Sutherland G , Bissett I P , O'Grady G 
Published: April 2020

Abstract

Background
High-output enterostomies and enteroatmospheric fistulas are common causes of intestinal failure, and may necessitate parenteral nutrition and prolonged hospital stay. Reinfusing lost chyme into the distal gut is known to be beneficial, but implementation has been limited because manual reinfusion is unpleasant and labour-intensive, and no devices are available. A new device is presented for reinfusing chyme easily and efficiently, with first-in-human data.

Methods
The device comprises a compact centrifugal pump that fits inside a standard stoma appliance. The pump is connected to an intestinal feeding tube inserted into the distal intestinal limb. The pump is activated across the appliance by magnetic coupling to a hand-held driver unit, effecting intermittent bolus reinfusion while avoiding effluent contact. Safety, technical and clinical factors were evaluated.

Results
Following microbiological safety testing, the device was evaluated in ten patients (median duration of installation 39·5 days; total 740 days). Indications included remediation of high-output losses (8 patients), dependency on parenteral nutrition (5), and gut rehabilitation before surgery (10). Reinfusion was well tolerated with use of regular boluses of approximately 200 ml, and no device-related serious adverse events occurred. Clinical benefits included resumption of oral diet, cessation of parenteral nutrition (4 of 5 patients), correction of electrolytes and liver enzymes, and hospital discharge (6 of 10). Of seven patients with intestinal continuity restored, one experienced postoperative ileus.

Conclusion
A novel chyme reinfusion device was developed and found to be safe, demonstrating potential benefits in remediating high-output losses, improving fluid and electrolyte balance, weaning off parenteral nutrition and improving surgical recovery. Pivotal trials and regulatory approvals are now in process.
Replacement and desmoplastic histopathological growth patterns in cutaneous melanoma liver metastases: frequency, characteristics, and robust prognostic value
Authors: Barnhill Raymond , van Dam Pieter‐Jan , Vermeulen Peter , Champenois Gabriel , Nicolas André , Rawson Robert V , Wilmott James S , Thompson John F , Long Georgina V , Cassoux Nathalie , Roman‐Roman Sergio , Busam Klaus J , Scolyer Richard A , Lazar Alexander J , Lugassy Claire 
Published: April 2020

AbstractAmong visceral metastatic sites, cutaneous melanoma (CM) metastasises initially to the liver in ~14–20% of cases. Liver metastases in CM patients are associated with both poor prognosis and poor response to immunotherapy. Histopathological growth patterns (HGPs) of liver metastases of the replacement and desmoplastic type, particularly from colorectal cancer and uveal melanoma (UM), may impart valuable biological and prognostic information. Here, we have studied HGP in 43 CM liver metastases resected from 42 CM patients along with other prognostic factors from three institutions. The HGPs (replacement, desmoplastic, pushing) were scored at the metastasis–liver interface with two algorithms: (1) 100% desmoplastic growth pattern (dHGP) and any (≥1%) replacement pattern (any‐rHGP) and (2) >50% dHGP, >50% rHGP or mixed (<50% dHGP and/or rHGP, pushing HGP). For 1 patient with 2 metastases, an average was taken to obtain 1 final HGP yielding 42 observations from 42 patients. 22 cases (52%) had 100% dHGP whereas 20 (48%) had any replacement. Cases with rHGP demonstrated vascular co‐option/angiotropism. With the development of liver metastasis, only rHGP (both algorithms), male gender and positive resection margins predicted diminished overall survival (p = 0.00099 and p = 0.0015; p = 0.034 and p = 0.024 respectively). On multivariate analysis, only HGP remained significant. 7 of 42 (17%) patients were alive with disease and 21 (50%) died with follow‐up after liver metastases ranging from 1.8 to 42.2 months (mean: 20.4 months, median: 19.0 months). 14 (33%) patients with previously‐treated metastatic disease had no evidence of disease at last follow up. In conclusion, we report for the first time replacement and desmoplastic HGPs in CM liver metastases and their prognostic value, as in UM and other solid cancers. Of particular importance, any rHGP significantly predicted diminished overall survival while 100% dHGP correlated with increased survival. These results contribute to a better understanding of the biology of CM liver metastases and potentially may be utilised in managing patients with these metastases.
Identifying fibroblast growth factor receptor genetic alterations using RNA‐based assays in patients with metastatic or locally advanced, surgically unresectable, urothelial carcinoma who may benefit from erdafitinib treatment
Authors: Wang Songbai , Burgess Mike , Major Christopher , English Alistair , Sweeney Maranna , Hartmann Arndt 
Published: April 2020

AbstractErdafitinib, a pan‐fibroblast growth factor receptor (FGFR) inhibitor received accelerated approval from the US Food and Drug Administration (FDA) for locally advanced or metastatic urothelial carcinoma (mUC) in adult patients with specific FGFR3/2 genetic alterations who progressed during or after ≥1 line of prior platinum‐containing chemotherapy (PCC), including within 12 months of neoadjuvant or adjuvant PCC. Concordance between the clinical trial assay (CTA) used in a phase 2 study and QIAGEN's therascreen® FGFR kit (a two‐step, multiplex, real‐time, RT‐PCR assay), the FDA‐approved companion diagnostic (CDx) with erdafitinib, was evaluated in this bridging study. Study samples included 100 CTA‐confirmed FGFR‐positive samples from 100 erdafitinib‐treated mUC patients, plus 200 CTA‐confirmed FGFR‐negative samples from the phase 2 study. The primary objective was met if the lower bound of 95% CI of objective response rate (ORR) in CDx‐confirmed patients with FGFR alterations was >25%. Demographics were similar between the bridging study and CTA‐screened patients. In total, 292 of 300 samples (97.3%) with valid CDx results showed high analytical concordance versus CTA (percent agreement [95% CI]: positive percent agreement, 87.2 [79.0; 92.5]; negative percent agreement, 97.0 [93.5; 98.6]; overall percent agreement, 93.8 [90.5; 96.1]). Investigator‐assessed ORR in the 81 CDx‐identified, erdafitinib‐treated patients who tested positive for both assays was 45.7% (95% CI: 35.3%; 56.5%) versus 40.4% (95% CI: 30.7%; 50.1%) for CTA and met the criteria for primary objective. High ORR and clinical concordance to CTA suggest that QIAGEN's CDx can reliably select mUC patients who would potentially benefit from erdafitinib treatment.