bluuebunny/crossref_metadata_2025_split huggingface dataset:
Encounters—Ongoing
Authors: Kalache Hiba 
Published: November 2019

Abstract
The series of drawings, Encounters – ongoing stems from chance meetings on leisurely road trips around the mountains of Lebanon. The drawings act as markers of my conversations with landowners, farmers, and people directly working in the fields. The formal particularities of drawing, and specifically the use of ink washes, allows for an approach that is both intuitive and intentional. This approach reproduces the spontaneity of these accidental or brief exchanges with people who have a vested interest in Lebanese land. Each conversation is represented by a simple tree branch, or a fragment of a (flowering) plant, belonging to the site and moment the encounter took place. This fragment indexes an encounter in which the farmer's story, experience, or relationship to the land and its borders was shared. Excerpts from our exchanges are also hand-written in Arabic on the picture plane. In the directness of the creative process, and the abstraction of the conversations, this project alludes to, and yet blurs, the sectarian divisions upon which the ownership of land is based, as well as a present geopolitical context. What I share is the marking of unplanned encounters through the representations of fragmented personal accounts along specific terrains and borders.
Failed Suppression of Salient Stimuli Precedes Behavioral Errors
Authors: Feldmann-Wüstefeld Tobias , Busch Niko A. , Schubö Anna 
Published: November 2019

Abstract
Our visual system is constantly confronted with more information than it can process. To deal with the limited capacity, attention allows us to enhance relevant information and suppress irrelevant information. Particularly, the suppression of salient irrelevant stimuli has shown to be important as it prevents attention to be captured and thus attentional resources to be wasted. This study aimed at directly connecting failures to suppress distraction with a neural marker of suppression, the distractor positivity (Pd). We measured participants' EEG signal while they performed a visual search task in which they had to report a digit inside a shape target while ignoring distractors, one of which could be a salient color singleton. Reports of target digits served as a behavioral index of enhancement, and reports of color distractor digits served as a behavioral index of failed suppression, each measured against reports of neutral distractor digits serving as a baseline. Participants reported the target identity more often than any distractor identity. The singleton identity was reported least often, suggesting suppression of the singleton below baseline. Suppression of salient stimuli was absent in the beginning and then increased throughout the experiment. When the singleton identity was reported, the Pd was observed in a later time window, suggesting that behavioral errors were preceded by failed suppression. Our results provide evidence for the signal suppression hypothesis that states salient items have to be actively suppressed to avoid attentional capture. Our results also provide direct evidence that the Pd is reflecting such active suppression.
« Des perles dans leur coquillage » ? Les femmes et la réinvention du patriarcat dans l’Algérie coloniale (1882–1962)
Authors: Jomier Augustin 
Published: November 2019

Résumé
L’anthropologie des années 1960–1970 et l’apologétique musulmane véhiculent des visions fixistes des femmes au Maghreb. Combinées à la rareté des sources, ces idées font obstacle à la connaissance historique. À partir du cas du Mzab, une région du nord du Sahara algérien à la population majoritairement berbérophone et ibadite, cet article propose des pistes pour historiciser la condition des Algériennes durant la période coloniale. Là où Elizabeth Thompson a montré que le patriarcat a été réinventé et renforcé dans la Syrie mandataire par l’alliance des élites locales et de l’administration, cet article montre que la médiation de maîtresses femmes au Mzab a été indispensable au renforcement de la domination masculine. Un groupe de femmes savantes et pieuses, nommées les laveuses des mortes, y enseignaient la religion aux femmes et secondaient les lettrés ibadites dans leur mission. Elles furent les indispensables agents de la domination masculine, et virent leur agency accrue.
Investigating the Role of the Tibetan Plateau in the Formation of Pacific Meridional Overturning Circulation
Authors: Wen Qin , Yang Haijun 
Published: November 2019

AbstractThe effects of the Tibetan Plateau (TP) on the Pacific Ocean circulation are investigated using a fully coupled climate model. Sensitivity experiments are designed to demonstrate that the presence of the TP is the reason for the lack of strong deep water formation in the subpolar North Pacific, because removing the TP in the model would enable the establishment of the Pacific meridional overturning circulation (PMOC). The processes involved are described in detail as follows. Removing the TP in the model would excite an anomalous high pressure over the subpolar North Pacific, causing anomalous Ekman downwelling that enhances surface water subduction north of 40°N. Removing the TP would also lead to less freshwater flux into the western Pacific, increasing sea surface salinity over the region. The high-salinity surface water can then be advected northward and eastward by the Kuroshio and its extension, subducting along the 26–27σθ isopycnal surfaces to the deeper ocean, which enables the formation of deep water in the North Pacific and the setup of the PMOC. Afterward, more high-salinity warm water would be transported from the tropics to the extratropics by the Kuroshio, leading to the establishment of the PMOC. The role of the Rocky Mountains is also examined in this study. We conclude that the Rocky Mountains may play a trivial role in modulating the meridional overturning circulations in both the Pacific and Atlantic Oceans.
Topographic Rainfall of Tropical Cyclones past a Mountain Range as Categorized by Idealized Simulations
Authors: Huang Ching-Yuang , Chou Cher-Wei , Chen Shu-Hua , Xie Jia-Hong 
Published: November 2019

Abstract
Topographic rainfall induced by westbound tropical cyclones past an island mountain is investigated using an idealized Weather Research and Forecasting (WRF) Model. Idealized simulations with varying vortex core size R (100–250 km), vortex intensity Vmax (20–35 m s−1), and steering wind speed U (4–10 m s−1) are conducted. The results show that the geometric distributions of major rainfall over the island are not greatly sensitive to cloud microphysics schemes using either single momentum or double momentum. Major rainfall is produced over northeastern and southwestern slopes of the mountain for smaller U. As U is doubled, the rainfall, however, is considerably weakened or is present only over southwestern slopes. For smaller U, a bifurcation of island rainfall with a sudden change in intensity or geometric shifting exists within a tiny range of R or Vmax. When the bifurcation occurs with small track deviations, geometric distributions of major rainfall are also more sensitive to cloud microphysics schemes. Such formation of bifurcation or double-peak rainfall, however, is significantly reduced when the terrain size is doubled. Systematic experiments are conducted to relate the topographical rainfalls over the northern half, southern half, and the whole of the mountain slopes to varying R, Vmax, and U. Larger U tends to produce much larger southern rainfall than northern rainfall. The average and maximum rainfalls generally increase with increased Vmax, except for large R. The decrease of average rainfall and maximum rainfall with increased U is more evident for smaller R, while not necessarily true for larger R.
Mania and psychosis associated with right parietal meningioma
Authors: Moore Emily , Srivastava Anshuman A , Rajaram Manoharan Senthil Vel Rajan , Hussain Najeeb 
Published: November 2019

Objective Meningioma is the most common type of primary central nervous system and intracranial tumor, and psychiatric changes attributed to meningioma include depression, apathy, psychosis, and personality changes. We present a case of a 59-year-old man with right parietal meningioma who developed mania with psychotic features throughout multiple hospitalizations. Method Single-case report. Results The patient originally presented with headache and bilateral lower extremity weakness. He was found to have a large medial sphenoidal wing meningioma and a small right parietal meningioma. The sphenoidal wing meningioma was removed via craniotomy, but the right parietal meningioma was not resected. In the following years, the patient developed symptoms of mania and psychosis which coincided with an increase in size of the right parietal meningioma. Conclusions Previous studies have linked right parietal meningioma to psychosis, but this case is one of the first to suggest that right parietal meningioma may be associated with the development of mania along with psychotic features.
Hormone replacement therapy with L-thyroxine promotes working memory and concentration in thyroidectomized female patients after differentiated thyroid carcinoma
Authors: Cordes Joachim , Woite Maya , Engelke Christina , Regenbrecht Gunnar , Kahl Kai G , Schmidt-Kraepelin Christian , Henning Uwe , Kamp Daniel , Klimke Ansgar 
Published: November 2019

Objective It is well established that long-term hypothyroidism is associated with cognitive deficits. Based on recent literature, we hypothesized that pharmacologically induced euthyroidism would lead to improved cognitive performance compared to a hypothyroid state. Methods We analyzed data from 14 nondepressed thyroidectomized female patients after differentiated thyroid carcinoma during hypothyroidism (due to a four-week withdrawal of thyroid hormone, T1) and euthyroidism brought about by substitution with L-thyroxine (T2). At both measurement points, patients completed a cognitive test battery as our dependent measure and Beck’s Depression Inventory to control depressive states. Results A Wilcoxon signed-rank tests revealed a significant improvement in the Rey–Osterrieth complex figure test (cognitive reproduction), Z = −3.183, p = 0.001, and the D2 concentration score, Z = −1.992, p = 0.046 in euthyroidism compared to hypothyroidism. Conclusions Our results confirm that hormone replacement therapy with L-thyroxine promotes cognitive reproduction and concentration in thyroidectomized female patients after differentiated thyroid carcinoma.
An experimental model of veno-venous arterial extracorporeal membrane oxygenation
Authors: Belliato Mirko , Caneva Luca , Aina Alessandro , Degani Antonella , Mongodi Silvia , Prahl Wittberg Lisa , Pellegrini Carlo , Broman Lars M , Iotti Giorgio Antonio 
Published: November 2019

Introduction: Veno-venous arterial extracorporeal membrane oxygenation is a hybrid-modality of extracorporeal membrane oxygenation combining veno-venous and veno-arterial extracorporeal membrane oxygenation. It may be applied to patients with both respiratory and cardio-circulatory failure. Aim: To describe a computational spreadsheet regarding an ex vivo experimental model of veno-venous arterial extracorporeal membrane oxygenation to determine the return of cannula pairs in a single pump–driven circuit. Methods: We developed an ex vivo model of veno-venous arterial extracorporeal membrane oxygenation with a single pump and two outflow cannulas, and a glucose solution was used to mimic the features of blood. We maintained a fixed aortic impedance and physiological pulmonary resistance. Both flow and pressure data were collected while testing different pairs of outflow cannulas. Six simulations of different cannula pairs were performed, and data were analysed by a custom-made spreadsheet, which was able to predict the flow partition at different flow levels. Results: In all simulations, the flow in the arterial cannula gradually increased differently depending on the cannula pair. The best cannula pair was a 19-Fr/18-cm arterial with a 17-Fr/50-cm venous cannula, where we observed an equal flow split and acceptable flow into the arterial cannula at a lower flow rate of 4 L/min. Conclusion: Our computational spreadsheet identifies the suitable cannula pairing set for correctly splitting the outlet blood flow into the arterial and venous return cannulas in a veno-venous arterial extracorporeal membrane oxygenation configuration without the use of external throttles. Several limitations were reported regarding fixed aortic impedance, central venous pressure and the types of cannulas tested; therefore, further studies are mandatory to confirm our findings
Intrathoracic retention of insoluble hyaluronic acid and its absorption process in rats
Authors: Uemura Akiko , Ogawa Shingo , Tanaka Ryou 
Published: November 2019

Background: Post-thoracotomy adhesions are frequent postoperative complications. It has been reported that insoluble hyaluronic acid may prevent adhesions. Materials and methods: This study had two objectives: first, to determine the in vivo degradation and absorption process, as well as the intrathoracic retention, of solid insoluble hyaluronic acid membrane; and second, to elucidate the association between postoperative intrathoracic retention and the morphological changes of insoluble hyaluronic acid in 12 Wistar rats. Insoluble hyaluronic acid membranes were cut into 2.0 cm × 1.0 cm rectangles in a dry state. After weighing, the test membranes were soaked and washed with saline to be implanted after pericardiotomy via thoracotomy. At Days 4, 7, 10, 14, and 28 after implantation, the rats were euthanized, the chest was opened, and the condition and implantation site of the inserted test membrane were examined. Results: Although approximately 10 days were required for the test membrane to decrease to half in the thoracic cavity, the intrathoracic remnant decreased to a mean of ~2% just 4 days later. Conclusion: This study clarified the time-dependent degradation process and remnants of insoluble hyaluronic acid in the thoracic cavity. A close relationship between the intrathoracic remnant of insoluble hyaluronic acid and its morphological change associated with degradation was demonstrated.
Simulation in Social Work Education: A Scoping Review
Authors: Kourgiantakis Toula , Sewell Karen M. , Hu Ran , Logan Judith , Bogo Marion 
Published: November 2019

Purpose: This article presents a scoping review that synthesized empirical studies on simulation in social work (SW) education. The review maps the research examining characteristics of simulation studies in SW education and emerging best practices. Method: Using Arksey and O’Malley’s scoping review framework to develop the methodology and following the PRISMA-ScR checklist, we selected 52 studies for this review. Results: Most studies were published in North America and included quantitative (37%), qualitative (31%), and mixed methods (33%). Simulation was used to teach generalist and specialized practice with interprofessional practice as the highest area of specialization. Simulation was also used for assessment purposes, and the Objective Structured Clinical Examination was a commonly reported method. We identified several facilitators and barriers to using simulation effectively for teaching and assessment. Conclusions: Our analysis permitted us to identify emerging best practices that can be used to guide teaching. Implications for SW research, teaching, and practice are discussed.
Sex-related differences in exercise performance and outcome of patients with hypertrophic cardiomyopathy
Authors: Ghiselli Luca , Marchi Alberto , Fumagalli Carlo , Maurizi Niccolò , Oddo Andrea , Pieri Francesco , Girolami Francesca , Rowin Ethan , Mazzarotto Francesco , Cicoira Mariantonietta , Ribichini Flavio , Arretini Anna , Targetti Mattia , Passantino Silvia , Cecchi Franco , Marchionni Niccolò , Maron Martin , Mori Fabio , Olivotto Iacopo 
Published: November 2019

Aims
Exercise performance is known to predict outcome in hypertrophic cardiomyopathy (HCM), but whether sex-related differences exist is unresolved. We explored whether functional impairment, assessed by exercise echocardiography, has comparable predictive accuracy in females and males with HCM.

Methods
We retrospectively evaluated 292 HCM patients (46 ± 16 years, 72% males), consecutively referred for exercise echocardiography; 242 were followed for 5.9 ± 4.2 years.

Results
Peak exercise capacity was 6.5 ± 1.6 metabolic equivalents (METs). Sixty patients (21%) showed impaired exercise capacity (≤5 METs). Exercise performance was reduced in females, compared with males (5.6 ± 1.6 vs 6.9 ± 1.5 METs, p &lt; 0.001; peak METs ≤ 5 in 40% vs 13%, p &lt; 0.001), largely driven by a worse performance in women &gt;50 years of age. At multivariable analysis, female sex was independently associated with impaired exercise capacity (odds ratio: 4.67; 95% confidence interval (CI): 1.83–11.90; p = 0.001). During follow-up, 24 patients (10%) met the primary endpoint (a combination of cardiac death, heart failure requiring hospitalization, sustained ventricular tachycardia, appropriate implantable cardioverter defibrillator discharge, resuscitated sudden cardiac death and cardioembolic stroke). Event-free survival was reduced in females (p = 0.035 vs males). Peak METs were inversely related to outcome in males (hazard ratio (HR) per unit increase: 0.57; 95% CI: 0.39–0.84; p = 0.004) but not in females (HR: 1.22; 95% CI: 0.66–2.24; p = 0.53).

Conclusions
Female patients with HCM showed significant age-related impairment in functional capacity compared with males, particularly evident in post-menopausal age groups. While women were at greater risk of HCM-related complications and death, impaired exercise capacity predicted adverse outcome only in men. These findings suggest the need for sex-specific management strategies in HCM.
Analysis of FDA Warning Letters Issued to Indian Pharmaceutical and Medical Device Companies: A Retrospective Study
Authors: Bablani Shray , Janodia Manthan D. 
Published: November 2019

Background: FDA issues warning letters to pharmaceutical manufacturers, distributors, or clinical investigators if it observes serious violations of federal regulations. These warning letters contain the details about the nature of the violations observed and the corrective actions recommended by the FDA. A follow-up inspection may be requested by the recipient after taking the corrective actions. Methods: Analysis of warning letters issued to Indian pharmaceutical companies from January 1, 2005, to December 31, 2018, was carried out. The warning letters were extracted from FDA’s public database. Results: Across the 14-year study period, the number of warning letters issued to Indian pharmaceutical and medical device manufacturers has gradually increased. Of all the violations listed in these warning letters, 85.87% were related to the failure of compliance with the cGMP guidelines. Moreover, 80.72% of these warning letters were not followed by a close-out warning, which indicated that the violations listed in these warning letters could not be resolved. Conclusion: As the inability of the recipients to comply with the cGMP guidelines formed the majority of the violations observed in the warning letters, more resources and manpower have to be assigned to the manufacturing process of the pharmaceutical products.
The Utility of Echocardiography for Non-ST-Segment Elevation Myocardial Infarction: A Retrospective Study
Authors: Ha Edward T. , Cohen Marc , Fields Paul J. , Van Daele Jessie , Gaeta Theodore J. 
Published: November 2019

Objective: The objectives were to assess factors associated with a higher likelihood of predicting acute coronary atherothrombosis (ACA) in non-ST-segment elevation myocardial infarction (NSTEMI), evaluate the impact of adding echocardiographic data, and develop an algorithm that would reduce overutilization of emergent angiography. Methods: Data were retrospectively analyzed on a patient cohort presenting to an emergency department of an urban community hospital with NSTEMI from October 1, 2015, to July 31, 2018. The inclusion criterion was any adult patient with a first-time, primary diagnosis of NSTEMI without high-risk features. The main outcome variables were the presence of ACA on angiography. Results: Seventy-three patients with NSTEMI were included in this study. Logistic regression analysis identified the following independent variables useful for predicting ACA: age, wall motion abnormality on echo, and levels of low-density lipoprotein. The model’s overall fit was highly significant ( P = .0012). Conclusion: An integrative approach was demonstrated for the management of patients with NSTEMI presenting to the hospital. Although the positive predictive value of echo in predicting ACA was limited, when combined with demographic attributes and risk factors, it proved to be successful in determining the need for angiography in patients with NSTEMI.
The effect of cooling rate on immiscible silicate liquid microstructure: an example from the Palaeogene dykes of Northeast England
Authors: Honour Victoria C. , Holness Marian B. , Stock Michael J. 
Published: November 2019

AbstractThe migration and accumulation of immiscible silicate liquids may play a significant role in the differentiation of crustal magma bodies and the formation of some economic mineral deposits. However, our understanding of the processes that control the segregation of these liquids is currently limited by the short timescales of petrological experiments. Detailed microstructural investigations of Palaeogene basaltic dykes from Northeast England, coupled with simple 1D thermal models, constrain the effects of cooling rate on the microstructure of unmixed immiscible silicate liquids under natural conditions. The size of unmixed Fe-rich droplets within a continuous silicic phase is related to the cooling rate by a power law, with droplet diameter increasing with decreasing cooling rate, accompanied by an increase in the number of droplets. Fe-rich droplet coarsening is a result of diffusion-controlled growth. The average apparent aspect ratio and grain size of matrix plagioclase crystals indicate that nucleation and growth of these grains probably occurred in a static (or only weakly convecting) fluid dynamical regime.
Transcriptome profiling analysis of sex-based differentially expressed mRNAs and lncRNAs in the brains of mature zebrafish (Danio rerio)
Authors: Yuan Wenliang , Jiang Shouwen , Sun Dan , Wu Zhichao , Wei Cai , Dai Chaoxu , Jiang Linhua , Peng Sihua 
Published: November 2019

Abstract

Background
Similar to humans, the zebrafish brain plays a central role in regulating sexual reproduction, maturation and sexual behavior. However, systematic studies of the dimorphic patterns of gene expression in the brain of male and female zebrafish are lacking.

Results
In this study, the mRNA and lncRNA expression profiles were obtained from the brain tissue samples of the three male and three female zebrafish by high-throughput transcriptome sequencing. We identified a total of 108 mRNAs and 50 lncRNAs with sex-based differential expression. We randomly selected four differentially expressed genes for RT-qPCR verification and the results certified that the expression pattern showed a similar trend between RNA-seq and RT-qPCR results. Protein-protein interaction network analysis, Gene Ontology (GO) analysis, and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were performed to obtain the biological significance of differentially expressed mRNA in the brain dimorphism of zebrafish. Finally, a Pearson correlation analysis was performed to construct the co-expression network of the mRNAs and lncRNAs.

Conclusions
We found that 12 new lncRNAs not only have significant gender specificity in the brain of zebrafish, and this finding may provide a clue to further study of the functional difference between male and female zebrafish brain.