bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of hormonal profile and some stress biomarkers in infertile couples in Abuja, Nigeria
Authors: Abriba Simon P. , Osadolor Humphrey B. 
Published: March 2020

Background: Infertility is a growing gynaecological problem in couples of childbearing age having difficulties bearing children. Couples with infertility are known to present with high levels of stress and psychopathology A cross sectional case control study aimed at evaluating the hormonal profile, some stress biomarkers, sperm analysis in infertile couples was carried out to ascertain their contributions to infertility in couples of child bearing age.Methods: Serum Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), Prolactin, Progesterone, Estrogen (E2), Testosterone, Salivary Cortisol and Salivary Alpha Amylase were evaluated using both competitive and non-competitive Enzyme Linked Immunosorbent Assay (ELISA) techniques; while sperm cells analysis were evaluated using conventional methods, in 164 infertile couples (study) and 100 fertile couples (control) attending fertility clinic in General Hospitals in Abuja, Nigeria.Results: The mean serum Prolactin and Salivary (S) Cortisol in the female were significantly higher (p<0.05) in the study group relative to the control group, while Salivary Alpha Amylase and LH show no significant difference (p>0.05) between the two groups. FSH, Progesterone and E2 in the female were significantly lower in the study group (p<0.05) compared with control group. Testosterone, FSH, Sperm cells count and Sperm activity (%) were significantly lower (p<0.05) in the male study group relative to the control group; while prolactin, S. cortisol and S. amylase were significantly higher (p<0.05) in the male study group relative to the control group. Conclusions: Abnormal hormones values and abnormal sperm quality and quantity are associated with elevated stress biomarkers in couples presenting with infertility. Strong positive correlations exist between hormones and stress biomarker in infertility conditions.
Hair tourniquet syndrome of labia minora in 14 year teen: a rare case report
Authors: Nutan Kumari , Jain Ajay Kumar 
Published: March 2020

Hair tourniquet syndrome (HTS) is rare clinical phenomenon in which body appendage is circumferentially entangled by string of hair leading to ischemia and necrosis or even autoamputation of the appendage. HTS commonly affects toes, finger or genitalia. Early diagnosis and prompt intervention lead to good outcome. This article presents a case of hair tourniquet syndrome of labia minora, a rare presentation in 14 year child.
Diagnostic capabilities of the vestibular evoked myogenic potential test in children with vestibular dysfunction
Authors: Madzharova Kalina I. , Beshkova Ana P. 
Published: March 2020

<p class="abstract"><strong>Background:</strong> Vestibular evoked myogenic potential (VEMP) testing is used in the diagnosis of vestibular disorders. It is an objective method for testing the the otolith organs of the vestibular system. VEMP test is an additional method for diagnosing vestibular neuritis (VN). The combination of cervical VEMP (cVEMP) and ocular VEMP (oVEMP) testing has an advantage in long-term monitoring of patients with VN. The VEMP test is well-studied for adults but studies involving children are insufficient. The aim of this study was to analysis and evaluation of the results from VEMP testing of children diagnosed with vestibular dysfunction. Analysis and evaluation of the results from VEMP testing of children diagnosed with vestibular dysfunction.</p><p class="abstract"><strong>Methods:</strong> History, examination of ENT organs, tone threshold audiometry, tympanometry, otoneurological examination, VEMP test. </p><p class="abstract"><strong>Results:</strong> Children with vestibular dysfunction who were examined showed changes predominantly in the oVEMP test. The upper branch of the vestibular nerve is affected. </p><p class="abstract"><strong>Conclusions:</strong> The VEMP test is an additional method for diagnosing patients with vestibular dysfunction. It is safe when used for children.</p>
Role of video head impulse test to indentify the site of lesion in patients with vestibular neuronitis
Authors: Pradhananga Rabindra Bhakta , Gyawali Bigyan Raj , Bhattarai Bebek 
Published: March 2020

<p class="abstract"><strong>Background:</strong> Vestibular neuronitis is one of the common causes of peripheral vertigo. Mostly the diagnosis of this entity is on clinical grounds. With the advent of video head impulse test (VHIT), assessment of function of all the semicircular canals has been possible based on principle of vestibulo-ocular reflex (VOR). The rationale of our study was to identify the affected branch of vestibular nerve in cases with clinical suspicion of vestibular neuronitis by measuring VOR gain and saccades using VHIT.</p><p class="abstract"><strong>Methods:</strong> This was a retrospective study carried out in the Department of ENT, Head &amp; Neck Surgery of Institute of Medicine, Kathmandu, Nepal. Record files of patients who attended OPD between October 2017 to October 2018 with the clinical diagnosis of peripheral vestibular neuronitis were assessed. A total of 13 cases were included in the study. VHIT records of the cases were assessed for VOR gain and saccades. Normal contralateral canals were taken as control. Paired t-test was used to compare the statistical significance of gain asymmetry and presence of saccades between the affected side and normal side. </p><p class="abstract"><strong>Results:</strong> Of 13 cases, 11 had isolated involvement of lateral semicircular canal and 2 cases had isolated involvement of posterior semicircular canal. Average gain was 0.68 in both groups. Presence of overt and covert saccades was seen in all the affected canals.</p><p class="abstract"><strong>Conclusions:</strong> VHIT, in cases with vestibular neuronitis, is a good test not only to confirm the diagnosis but also to identify the division of vestibular nerve involved.</p>
Results of cartilage shield tympanoplasty in revision cases of myringoplasty
Authors: Wadhera Raman , Gupta Keshav 
Published: March 2020

<p class="abstract"><strong>Background:</strong> Cartilage shield tympanoplasty (CST) is seen as a good option for revision surgery in cases of myringoplasty failure. Cartilage serves as rigid material which resists retraction. However, there have been concerns regarding hearing outcome and surveillance in follow up period.</p><p class="abstract"><strong>Methods:</strong> A prospective study was conducted at our tertiary institute. 25 patients of either sex in age group of 18-50 years with one or more failed tympanoplasties underwent CST. Pre-operative and post-operative audiograms were obtained, and patients were regularly followed up to calculate graft uptake and hearing outcome. Quantitative data was analyzed by using Student t-test and for qualitative data chi square test was used. </p><p class="abstract"><strong>Results:</strong> The mean pre-operative pure tone air-bone gap was 25.09±8.10 dB while the mean postoperative pure tone air-bone gap was 13.47±5.18 dB, one case (4%) presented with failure as there was a residual perforation antero-inferiorly. Since it was a small residual perforation, it was planned for closure by fat myringoplasty. No complications were recorded. We obtained graft take rate of 96% and mean postoperative gain of 11.62±7.11 dB in PTA-ABG.</p><p class="abstract"><strong>Conclusions:</strong> We recommend CST for revision cases of tympanoplasty.</p><p class="abstract"> </p>
Betel quid and tobacco chewing habits and its associated clinical findings in a rural tertiary care hospital
Authors: Reddy D. Indraneel , Narayana M. Lakshmi , Viswambharan Vivek , Chaithanya N. Reddy 
Published: March 2020

<p class="abstract"><strong>Background:</strong> Among all forms of tobacco, smokeless tobacco is known to be more carcinogenic than smoking according to various studies. Smokeless tobacco is consumed through various forms in our region like kaddipudi, gutkha, khaini, pan, etc. This study aims at evaluating the different chewing patterns of tobacco and to assess their impact on the oral mucosa.</p><p class="abstract"><strong>Methods:</strong> The patients who attended ENT department with the habit of chewing tobacco were taken into this study after considering the inclusion and exclusion criteria. A detailed questionnaire including various habits and chewing patterns were filled and received from all the subjects, and a comprehensive ENT examination was done for them. </p><p class="abstract"><strong>Results:</strong> In our study, a total of 120 subjects were included who chewed tobacco in various combinations, which we divided into 6 categories; of which 97 users were under category 2 (betel leaf, betel nut, slaked lime and kaddipudi). Among 120 subjects, 35 had malignancy, 51 potentially malignant lesions, 30 early changes and 4 had no changes. There was a statistically significant correlation noted between the duration of chewing for &gt;15 years (p=0.000); frequency of chewing &gt;5 times/day (p=0.004) and also overnight tobacco placement (p=0.027) with the occurrence of potentially malignant lesions and malignancy.</p><p class="abstract"><strong>Conclusions:</strong> In our study, the combination of betel leaf, betel nut, slaked lime with kaddipudi was the most commonly used combined form of smokeless tobacco. The duration, frequency of tobacco chewing, and overnight placement were statistically significant associated with potentially malignant lesions and malignant lesions.</p><p> </p>
A prospective analytic study of invasive fungal rhinosinsitis
Authors: Parmar Bhagirathsinh D. , Jha Sushil G. , Sinha Vikas , Chaudhari Nirav P. , Dave Gavendra P. 
Published: March 2020

<p class="abstract"><strong>Background:</strong> Fungal sinusitis is more commonly found in immunocompromised patients with systemic illnesses, e.g., uncontrolled diabetes mellitus, chronic renal failure, patient on prolonged systemic steroid therapy, hematological malignancies, HIV/AIDS, etc. Invasive fungal sinusitis is subdivided into acute and chronic. Less than 4 weeks duration separates the acute stage from the chronic stage of the disease. Management of invasive fungal sinusitis consists of sinonasal debridement with or without Caldwell-Luc surgery followed by antifungal therapy.</p><p class="abstract"><strong>Methods:</strong> Total 30 cases of both types of invasive fungal sinusitis were included in this study. The demographic profile, clinical presentation, underlying immunocompromised status, complication, mortality and management of all these 30 patients were analyzed. </p><p class="abstract"><strong>Results:</strong> Invasive fungal sinusitis was most commonly observed in 3<sup>rd</sup> and 4<sup>th</sup> decade of life with male predominance. Prolonged uncontrolled diabetic mellitus was the most common underlying immunocompromised status. Mucor was the most common isolated fungal species. Preseptal cellulitis was the most common complication.</p><p class="abstract"><strong>Conclusions:</strong> For early detection of mucosal changes one has to do endoscopic examination in all immunocompromised patients with symptoms like headache, facial or periorbital pain and swelling, purulent nasal discharge, etc. All clinician should think vigilantly in immunocompromised patients with above symptoms or in pyrexia of unknown origin not responding to antibiotics. To reduce mortality, one has to go for immediate sinonasal debridement even in local anaesthesia also if patient is not fit for general anaesthesia.</p><p> </p>
Angiectatic nasal polyp diagnostic quandary of sinonasal malignancy
Authors: Kashaf Nur Afeena A. F. A. , Chin Andrew H. K. , Ibrahim Zambri M. , Rahman Irnawati W. A. , Rahman Shakir K. A. 
Published: March 2020

<p class="abstract">Angiectatic nasal polyp (ANP) is a rare entity of inflammatory nasal polyp accounts for only 4 to 5% of all nasal polyp.It is often misdiagnosed as a malignant neoplasm due to its aggressive clinical presentation and radiological findings mimicking a neoplastic characteristic. achieving the diagnosis of ANP can be a challenge but crucial as management and prognosis of malignant and benign sinonasal tumour differs significantly. We describe a unique case of an ANP in a 33 year old gentleman presented with left sided nasal obstruction associated with blood stained nasal discharge, facial pain and left eye epiphora. There was proptosis of the left eye and his left nasolabial fold was obliterated due to a vague left cheek swelling. Clinical presentation was highly suspicious of malignancy. CT scan finding was also suggestive of malignant tumour with surrounding bony bowing and erosions, while MRI was reported as haemangioma. Post-surgery of left endoscopic medial maxillectomy, histopathology result was negative for malignancy. After revision of specimen done and further discussions, the diagnosis of ANP was made. Patient was postoperatively well with regression of symptoms along 5 months follow-up. ANPs are relatively uncommon pseudoneoplastic lesion that can cause a significant diagnostic dilemma as illustrated in this case. awareness of distinctive radiological and histopathological findings of ANP is important to establish the diagnosis and managed accordingly. However, little is known to guide the approach in such cases, therefore we find the case report to be noteworthy in this field.</p>
Parapharyngeal schwannomma: a case report
Authors: K. Manjunath , Singh Amardeep , V. Smitha 
Published: March 2020

<p class="abstract">Schwannomas are uncommon neurogenic tumors that are typically benign, slow growing, and asymptomatic. Upto 45% of schwannomas arise from the head and neck region, the sites of origin are: face, scalp, intracranial cavity, orbit, nasal and oral cavities, parapharyngeal space, middle ear, mastoid, larynx, and medial and lateral regions of the neck. The age distribution is 30 to 70 years and male:female 3:1. Symptoms and signs are neck swelling (54%), pain (11%), cranial nerve palsy (10%), oropharyngeal swelling (8%), dysphagia (6%) and trismus, otalgia (11%). This case is being presented because it is the rare case of neck swelling. A young male patient aged 22 yrs, presented with complains of swelling in right side of neck since 6 months. Patient also complains of difficulty in swallowing, difficulty in breathing and change in voice since 4 months. On examination of neck, a diffuse swelling noted at right level III neck, extending from the superior border of thyroid cartilage up to the level of hyoid bone. Horizontally the swelling was extending from mid thyroid cartilage till the anterior border of sternocleidomastoid muscle. On examination of swelling, a pink smooth globular mass seen pushing the right aryepiglottic fold anteriorly obscuring the laryngeal inlet. No pooling of saliva. elective tracheostomy was done, through lateral cervical approach, mass was excised in toto and extubated after 7 days.</p>
Dieta de Saccopteryx Leptura (chiroptera: emballonuridae) en un área exurbana del piedemonte llanero colombiano
Authors: Cruz-Parrado Karen , Moreno Gabriela , Sánchez Francisco 
Published: March 2020

Se estima que más del 70% de los murciélagos son consumidores de insectos y por lo tanto contribuyen al control de poblaciones de insectos. Algunos de esos insectos pueden ser plagas en cultivos agrícolas o vectores de enfermedades. Por lo anterior, estudiar la dieta de los murciélagos insectívoros es importante para determinar su valor potencial para los humanos. En este trabajo de investigación, se analizó la dieta de una colonia de Saccopteryx leptura, una especie tolerante a ambientes urbanos neotropicales de zonas bajas. Se recolectaron 24 muestras de heces de una colonia compuesta por entre siete y nueve individuos. Entre las presas de S. leptura se encontraron insectos de los órdenes Hymenoptera (dos morfoespecies), Coleoptera (dos morfoespecies), Hemiptera (dos morfoespecies), Blattodea (una morfoespecie) y Lepidoptera (una morfoespecie), siendo los dos primeros casi el 80% de las presas. Los últimos cuatro órdenes no habían sido registrados en la dieta de S. leptura. Entre las presas encontradas se incluyen coleópteros de la familia Curculionidae, y hemípteros de la familia Cicadellidae que con frecuencia son plagas en cultivos agrícolas. Estudios posteriores se centrarán en explorar estrategias para aprovechar los posibles servicios de este murciélago.
Oportunidades de investigación en preeclampsia, desde la perspectiva de prevención primaria. Un artículo de reflexión
Authors: Díaz-Martínez Luis Alfonso , Serrano-Díaz Norma Cecilia 
Published: March 2020

Introducción: en este ensayo se presentan algunos campos de investigación en los que, desde una perspectiva de prevención de la preeclampsia, es necesario trabajar para adelantar estudios e intervenciones de calidad, necesarios para esclarecer dudas o vacíos, todo con miras a reducir el impacto que la entidad tiene en nuestra población.Hechos: algunos de los campos en donde hay in-consistencias en la información disponible son los de la incidencia de la preeclampsia, sus factores de riesgo, las consecuencias a corto y largo plazo de sufrirla, la percepción que tienen las embarazadas sobre la preeclampsia, o la utilidad de muchas de las medidas de prevención poblacionales propuestas.Conclusiones: se propone que estas deficiencias se pueden resolver de una manera más eficiente al vincular los conocimientos que se tienen de la fisiopatología de la entidad con las estrategias de intervención e investigación en epidemiología y salud pública.
Embarazo posterior a cirugía bariátrica: complicaciones maternas y fetales
Authors: Hernández-Pinzón Jairo , Castillo-Zamora Marcos , Arango-Galvis Victoria E 
Published: March 2020

Objetivo: utilizando herramientas de revisiones sistemáticas, describir los efectos de la obesidad en el embarazo para la madre y el feto, así como describir las complicaciones perinatales, intraparto y posnatales en pacientes a las que se les ha practicado cirugía bariátrica.Metodología: se utilizó la base de datos Pubmed/Medline, los términos de búsqueda fueron: bariatric surgery AND/OR obstetric complications, pregnance, abortion, pregnancy outcomes, adverse pregnancy outcomes. Se hizo énfasis en guías de práctica clínica, se realizó búsqueda en sitios de sinopsis de la literatura médica del Database of Abstracts or Reviews of Effectiveness (DARE).Resultados: se seleccionaron 50 artículos, los cuales fueron sintetizados en la sección de resultados de la revisión. La cirugía bariátrica predispone a la isquemia intestinal y formación de hernias en los embarazos posteriores. También se han descrito deficiencias específicas de micronutrientes. Por otra parte, existen informes contradictorios sobre el efecto en el peso fetal.Conclusiones: el seguimiento de los embarazos después del primer año de la cirugía para pérdida de peso no informa episodios importantes de malnutrición materna o fetal. La evidencia muestra que los resultados del embarazo después de la cirugía bariátrica son favorables, en comparación con los resultados en los obesos no tratados quirúrgicamente, se necesitan más estudios prospectivos diseñados cuidadosamente para evaluar áreas de incertidumbre en este campo.
Síndrome de aglosia-adactilia y exposición prenatal a misoprostol ¿Relación causal o casual? Reporte de un caso
Authors: Ramírez-Cheyne Julián , Pachajoa Harry , Isaza Carolina , Saldarriaga Wilmar 
Published: March 2020

Introducción y objetivo: el síndrome de aglosia-adactilia es un síndrome polimalformativo congénito de muy baja frecuencia, con una etiología y patrón de herencia que no son claros. Se hace una búsqueda bibliográfica orientada a la asociación entre la exposición prenatal a misoprostol y malformaciones congénitas. Se presenta un caso de este síndrome asociado a exposición prenatal a misoprostol a las 10 semanas de gestación, asociación no establecida en la literatura revisada.Presentación del caso: recién nacido con características fenotípicas de síndrome de aglosia-adactilia, hijo de madre de 17 años, con antecedente de haber utilizado misoprostol en dosis de 400 microgramos vía oral y 200 microgramos vía vaginal a las 10 semanas de gestación, con el objetivo de interrumpir el embarazo.Discusión: el misoprostol es un análogo sintético de la prostaglandina E1, se ha asociado a un aumento en el riesgo de la ocurrencia de secuencia de Moebius, artrogriposis, síndrome de aglosia-adactilia, defectos de las extremidades de tipo terminal y transversal en madres que utilizan este medicamento durante el primer trimestre de gestación.
Actividad Fosfolipasa, Hemolítica y Bactericida preliminar del Veneno de la Serpiente de cascabel del Tolima
Authors: Solano Godoy Jennifer Alexandra , Molano Cardona Emerson David , Bernal Bautista Manuel Hernando , Murillo Arango Walter 
Published: March 2020

En el departamento del Tolima no hay estudios que permitan precisar con certeza la magnitud del accidente ofídico causado por Crotalus durissus, existiendo la necesidad de generar información sobre el perfil proteico, como forma de aproximación a la compresión de algunas actividades biológicas relacionadas con la toxicidad del veneno, así como su potencial biotecnológico. En este trabajo se analizó el perfil electroforético por SDS-PAGE del veneno crudo extraído de individuos colectados en el municipio de Natagaima (Tolima) y la asociación con actividades fosfolipasa, hemolítica directa e indirecta y bactericida sobre Escherichia coli, Staphylococcus aureus y Pseudomona aeuroginosa. El veneno crudo presentó bandas de peso molecular 26.6 kDa., 17, 14.2, 6.5, 3.5 y 1.06 kDa., correspondientes con otros reportes previos del veneno para la especie. Se presentaron niveles considerables de actividades hemolítica (200 µg) y fosfolipasa (1.25 UA/mg. ± 0.88) dependientes de Calcio, y el efecto bactericida del veneno crudo fue diferencial sobre los microorganismos evaluados, presentando actividad moderada sobre Escherichia coli. Los resultados constituyen datos valiosos que confieren un acercamiento hacia el conocimiento del potencial tóxico del veneno de Crotalus durissus (cascabel) de la zonade Natagaima-Tolima, así como de la capacidad bactericida y posibles aplicaciones futuras en campos de investigación relacionados con la búsqueda de nuevos agentes antimicrobianos.
Permainan Ular Tangga Berbasis Arduino UNO dan RFID Guna Mengembangkan Ilmu Pengetahuan Anak Sekolah Dasar dalam Mengenal Jenis Tanaman
Authors: Nusyirwan Deny , Guntara Aldo , Perdana Prasetya Perwira Putra 
Published: March 2020

Anak sekolah dasar kurang ingin memainkan sebuah permaianan yang menurutnya membosankan dan tertuju pada pemikiran yang menguras fikiran mereka, sebagai contohnya yaitu permainan hitung dan soal jawaban sebagai simulasi kecerdasan mereka, namun dari solusi tersebut ketertarikan mereka menurun, disebabkan karena belum adanya jawaban dari permasalahan yang membuat mereka tertarik akan permainan ilmu pengetahuan. Pada penelitian yang dilakukan oleh Samuel Gandang Gunanto seorang Mahasiswa Institut Seni Indonesia Yogyakarta, yang di terbitkan oleh Journal of animation and games studies pada Oktober 2016. Penciptaan karya ini dikembangkan segi imersif dari sebuah game yang nyata. Pembelajaran pendidikan karakter, secara khusus tentang sikap kepedulian terhadap kebersihan lingkungan. Dengan inovasi sebelumna, maka dapat dibandingkan dengan inovasi permaianan ular tangga, yang dikembangkan melalui permaianan manual berbasis digital. Cara kerjanya menggunakan RFID sebagai sarana pendeteksi jawaban jenis tanaman yang akan meningkatkan ilmu pengetahuan tentang tanaman. Penelitian dimulai dengan pendekatan Double Diamand yang diperkenalkan oleh British Design Council, yaitu memulai proses perancangan dengan social research yang di integrasikan dengan design thinking untuk dapat menghasilkan inovasi berbasis teknologi yang bermanfaat bagi masyarakat setempat. Setelah mendapatkan solusi utama, maka akan dilanjutkan dengan pembuatan sederhana yang akan dipergunakan untuk uji fungsi dan manfaat bersama calon pengguna.