Impact of an Education Programme on IBD Patients’ Skills: Results of a Randomised Controlled Multicentre Study [ECIPE]
Authors: Moreau J , Hammoudi N , Marthey L , Trang-Poisson C , Nachury M , Altwegg R , Grimaud J C , Orempuller S , Hébuterne X , Aubourg A , Baudry C , Seksik P , Roblin X , Nahon S , Savoye G , Mesnard B , Stefanescu C , Simon M , Coffin B , Fumery M , Carbonnel F , Peyrin-Biroulet L , Desseaux K , Allez M ,   GETAID, Brazier Franck , Dupas Jean-Louis , Fumery Mathurin , Leconte Martine , Bornet Annie , Bouhnik Yoram , Herbet Geraldine , Ostrec Suzanna , Stefanescu Carmen , Treton Xavier , Coffin Benoît , Coutarel Delphine , Romarin Joséphanne , Carbonnel Franck , Marthey Lysiane , Kail Valérie , Nachury Maria , Pariente Benjamin , Challier Stéphanie , Ducerne Mylène , Grimaud Jean-Charles , Lutgen Isabelle , Lebayle Valérie , Legoux Laetitia , Nahon Stéphane , Altwegg Romain , Caillo Ludovic , Peyrin-Biroulet Laurent , Benard Nelly , Boucard Béatrice , Bourreille Arnaud , Kerdreux Elise , Ferreira Katia , Trang-Poisson Caroline , Arab Nadia , Cluzeau Virginie , Eyraud Evalyne , Filippi Jerôme , Hébuterne Xavier , Paput Aurore , Rahill Amine , Armengol-De Beir Laura , Blot Julien , Foloppe Elise , Savoye Guillaume , Vienney Gaëlle , Simon Marion , Beaugerie Laurent , Bourrier Anne , Chafai Najim , Debove Clotilde , Hoyeau Nadia , Kirchgesner Julien , Landman Cécilia , Lefèvre Jérémie H , Nion-Larmurier Isabelle , Parc Yann , Seksik Philippe , Sokol Harry , Allez Matthieu , Baudry Clotilde , Bonnet Joëlle , Chedouba Leïla , Descrouet Nathalie , Hammoudi Nassim , Lepasteur Jean-Félix , Nisard Andrée , Vincent Marion , Chevret Sylvie , Desseaux Kristell , Berolo Regine , Del Tedesco Emilie , Roblin Xavier , Bergereau Emilie , Faure Patrick , Haenning Audrey , Lassailly Marianne , Moreau Jacques , Orempuller Sandra , Mesnard Bruno , Biskri Souheyla Mezrag , Tavernier Noémie , Verhaeghe Floriane , Vernier Gwenola , Aubourg Alexandre , Chauvigneau Magalie , Lamblin Charles , Lorin Marie-Christine , Picon Laurence 
Published: September 2020

Abstract

Background
Better patient knowledge on inflammatory bowel disease [IBD] could improve outcome and quality of life. The aim of this study was to assess if an education programme improves IBD patients’ skills as regards their disease.

Methods
The GETAID group conducted a prospective multicentre randomised controlled study. IBD patients were included at diagnosis, or after a significant event in the disease course. Patients were randomised between ‘educated’ or control groups for 6 months. Education was performed by trained health care professionals. A psycho-pedagogic score [ECIPE] was evaluated by a ‘blinded’ physician at baseline and after 6 and 12 months [M6 and M12]. The primary endpoint was the increase of ECIPE score at M6 of more than 20%.

Results
A total of 263 patients were included in 19 centres (male:40%; median age:30.8; Crohn’s disease [CD]:73%). Of these, 133 patients were randomised into the educated group and 130 into the control group. The median relative increase in ECIPE score at M6 was higher in the educated group as compared with the control group (16.7% [0–42.1%] vs 7% [0–18.8%], respectively, p = 0.0008). The primary endpoint was met in 46% vs 24% of the patients in the educated and control groups, respectively [p = 0.0003]. A total of 92 patients met the primary endpoint. In multivariate analysis, predictors of an increase of at least 20% of the ECIPE score were randomisation in the educated group (odds ratio [OR] = 2.59) and no previous surgery [OR = 1.92].

Conclusions
These findings support the set-up of education programmes in centres involved in the management of IBD patients.