bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection
Authors: Stressmann Franziska A. , Bernal-Bayard Joaquin , Perez-Pascual David , Audrain Bianca , Rendueles Olaya , Briolat Valérie , Bruchmann Sebastian , Volant Stevenn , Ghozlane Amine , Haussler Susanne , Duchaud Eric , Levraud Jean-Pierre , Ghigo Jean-Marc 
Published: April 2020

ABSTRACTThe long-known resistance to pathogens provided by host-associated microbiota fostered the notion that adding protective bacteria could prevent or attenuate infection. However, the identification of endogenous or exogenous bacteria conferring such protection is often hindered by the complexity of host microbial communities. Here, we used zebrafish and the fish pathogenFlavobacterium columnareas a model system to study the determinants of microbiota-associated colonization resistance. We compared infection susceptibility in germ-free, conventional and re-conventionalized larvae and showed that a consortium of 10 culturable bacterial species are sufficient to protect zebrafish. Whereas survival toF. columnareinfection does not rely on host innate immunity, we used antibiotic dysbiosis to alter zebrafish microbiota composition, leading to the identification of two different protection strategies. We first identified that the bacteriumChryseobacterium massiliaeindividually protects both larvae and adult zebrafish. We also showed that an assembly of 9 endogenous zebrafish species that do not otherwise protect individually confer a community-level resistance to infection. Our study therefore provides a rational approach to identify key endogenous protecting bacteria and promising candidates to engineer resilient microbial communities. It also shows how direct experimental analysis of colonization resistance in low-complexityin vivomodels can reveal unsuspected ecological strategies at play in microbiota-based protection against pathogens.
Open innovation and network dynamics. An analysis of openness of co-patenting collaborations in Florence, Italy
Authors: Capone Francesco , Innocenti Niccolò 
Published: April 2020

PurposeThe purpose of this paper is to investigate the relational dynamics for innovation and, in particular, the impact of the openness of innovation process on the innovation capacity of organisations in restricted geographical contexts.Design/methodology/approachThrough a negative binomial regression, the work analyses how the characteristics of the openness of the organisation’s innovation process in the period 2004-2010 influence the firm’s patent productivity in the following period (2011-2016).FindingsThe breadth of the open innovation (OI) process, here measured by the number of external network ties that an organisation realises for the realisation of its patents, has a positive effect on patent productivity. The depth of the openness, that is, the intensity of external network ties, has an equally positive influence on the innovative performance. However, after a tipping point, the patent productivity tends to decrease, underlining the costs and problems of OI practices.Research limitations/implicationsThis study considers only patent collaborations in the city of Florence. Therefore, it focusses on codified innovations and on a single territorial case study.Practical implicationsThe results underline the importance of the adoption of OI practices in restricted geographical contexts (such as cities, clusters or industrial districts) but with several limitations. Only collaborating more with others does not foster the organisation’s invention productivity, but different types of evidence are found here.Originality/valueAn original database has been created, containing all the information on patents realised in the area of Florence from 2004 until 2016, and a social networks analysis was applied to identify the local innovation networks.
Board of directors' characteristics and corporate risk disclosure: the moderating role of family ownership
Authors: Alshirah Malek Hamed , Abdul Rahman Azhar , Mustapa Ifa Rizad 
Published: April 2020

PurposeThis study aims at examining the level of risk of disclosure practices and the effect of four board of directors' characteristics (board size, board meetings, CEO duality and board expertise) on these practices in the Jordanian context. This study also adds to the body of literature by examining the moderating effect of family ownership on the relationship between the board of directors' characteristics and the corporate risk disclosure.Design/methodology/approachThe sample of this study contains the non-financial Jordanian firms listed on Amman Stock Exchange (ASE). 376 annual reports of the sampled firms over four years from 2014 to 2017 were used. The content analysis approach was used to collect data and to determine the level of risk disclosure by computing the number of risk-related sentences in the annual reporting. To test the study's hypothesis, the random effect model was employed.FindingsThe empirical results show that the total of the risk disclosure sentences for each firm ranges from a minimum value of 2 sentences to a maximum value of 61 sentences, and the mean of CRD is 28 sentences. The results also indicate that the board expertise is positively related with the level of risk disclosure. Conversely, CEO duality has a negative impact on the risk disclosure practices. However, the results failed to support that the board size and the board meetings have a significant effect on the level of risk disclosure. Furthermore, the study demonstrated that the family ownership moderates the relationship between the board of directors and the corporate risk disclosure.Practical implicationsThe finding of this study is more likely be useful for many concerned parties, researchers, authorities, investors and financial analysts alike in understanding the current practices of the risk disclosure in Jordan, thus helping them in reconsidering and reviewing the accounting standards and improving the credibility and transparency of the financial reports in the Jordanian capital market.Originality/valueThe current study contributes to the literature of risk disclosure because the previous research has paid little attention to this topic in Jordan. To the best knowledge of the researcher, this study is the first Jordanian study that focuses on examining the relationship between the board of directors' characteristics and the corporate risk disclosure in the non-financial sector. Furthermore, it is the first study that examines the moderating role of family ownership on such relationships. Consequently, the results of the current study draw attention to the CRD practices and the monitoring role of board of directors in Jordan.
Open collaboration between universities and enterprises: a case study on GitHub
Authors: Cheng Xiufeng , Zhang Ziming , Yang Yue , Yan Zhonghua 
Published: April 2020

PurposeSocial coding platforms (SCPs) have been adopted by scores of developers in building, testing and managing their codes collaboratively. Accordingly, this type of platform (site) enables collaboration between enterprises and universities (c-EU) at a lower cost in the form of online team-building projects (repositories). This paper investigates the open collaboration patterns between these two parties on GitHub by measuring their online behaviours. The purpose of this investigation is to identify the most attractive collaboration features that enterprises can offer to increase university students' participation intentions.Design/methodology/approachThe research process is divided into four steps. First, the authors crawled for numerical data for each interactive repository feature created by employees of Alibaba on GitHub and identified the student accounts associated with these repositories. Second, a categorisation schema of feature classification was proposed on a behavioural basis. Third, the authors clustered the aforementioned repositories based on feature data and recognised four types of repositories (popular, formal, normal and obsolete) to represent four open collaboration patterns. The effects of the four repository types on university students' collaboration behaviour were measured using a multiple linear regression model. An ANOVA test was implemented to examine the robustness of research results. Finally, the authors proposed some practical suggestions to enhance collaboration between both sides of SCPs.FindingsSeveral counterintuitive but reasonable findings were revealed, for example, those based on the “star” repository feature. The actual coding contribution of the repositories had a negative correlation with student attention. This result indicates that students were inclined to imitate rather than innovate.Originality/valueThis research explores the open collaboration patterns between enterprises and universities on GitHub and their impact on student coding behaviour. According to the research analysis, both parties benefit from open collaboration on SCPs, and the allocation or customisation of online repository features may affect students' participation in coding. This research brings a new perspective to the measurement of users' collaboration behaviour with output rates on SCPs.
Commute and labour productivity: investigation of inner city construction sites
Authors: Chaparro Daniel Alejandro , Ying Fei J. , Rotimi Funmilayo Ebun , Egbelakin Temitope 
Published: April 2020

Purpose
This paper aims to identify the impact that commute patterns pose on construction labour productivity (CLP). There is limited research focussed on the impact of workforce transportation on productivity, even fewer in a construction environment. In particular, this study seeks to fill a gap in the understanding of how commute patterns may influence CLP.

Design/methodology/approach
Key factors reported affecting CLP were identified through a comprehensive literature review. Data were collected from 27 interviews and observational evidence at construction sites on Auckland Central Business District (CBD).

Findings
Shortage of skills, communication among workers, shirking behaviour, absenteeism and tardiness were perceived as the most critical labour productivity factors that are influenced by commute patterns. It is considered that stressful commutes may lead to shirking behaviours (absenteeism and calling sick). Meanwhile, ridesharing may encourage communication among workers.

Research limitations/implications
The study was carried out in a central business district, focussing on a geographic area with its particular characteristics. The results, thus, may not be generalised in general urban settings.

Originality/value
The research outcomes can be used as guidelines for companies considering travel plans for their employees, to minimise the negative impact commuting can have on workers, especially in industries with low productivity.
Omnichannel fashion retailing: examining the customer decision-making journey
Authors: Lynch Samantha , Barnes Liz 
Published: April 2020

PurposeThe purpose of this paper is to examine the customer decision-making journey of high involvement female fashion consumers in the context of omnichannel fashion retailing.Design/methodology/approachThe research is qualitative in nature, using a multi-method approach consisting of focus groups, semi-structured interviews, online diaries and follow-up interviews, with grounded theory applied to analyse the data.FindingsThe results of the study include a framework to outline the stages of the omnichannel customer decision-making journey for young high involvement female fashion consumers. The findings also reveal that an omnichannel decision-making journey is the one that predicated on risk and that consumers employ specific strategies to avoid such risks.Research limitations/implicationsDue to the nature of this research, the sample size is limited and may not be generalised. Data collection was confined to Manchester, UK.Practical implicationsCustomer journey mapping enables practitioners to view the entire shopping experience through the eyes of the customer and enables retailers' fault-find issues within the customer and brand experience.Originality/valueThe paper advances knowledge about fashion and consumer behaviour. The customer decision journey framework maps the emotional experiences, devices and channels encountered by high-involvement fashion consumers across each stage of the omnichannel journey.
Risks in feasibility and viability appraisal process for property development and the investment market in Nigeria
Authors: Jagun Zainab Toyin 
Published: April 2020

PurposeThe feasibility and viability appraisal technique is becoming increasingly crucial in the planning systems, theory, applications and outputs for property development and project investments. This paper aims to account for the findings of the practices associated with risk in the feasibility and viability appraisal process. Also, it examines the need for a practical framework for conducting a feasibility and viability appraisal, which can be employed by estate surveyors and valuers in NigeriaDesign/methodology/approachThis study adopted purposive sampling techniques to administer 240 sets of questionnaires, out of which 210 sets were well-thought-out to be useable for the analysis after data screening. Statistical package for social sciences (SPSS), structural equation modelling (SEM) and analysis of movement structures (AMOS) were the main analytical tools used to carry out the reliability test, normality test, exploratory factor analysis, confirmatory factor analysis, measurement and structural model.FindingsThe analysis results indicated that the P-values of the various forms of concepts of risks in feasibility and viability appraisal process (preparation) for property development and the investment market was statistically significant: technological factor - 0.000; political factor- 0.000 and economic factor- 0.000. However, a non-significant effect was found with socio-environmental factors on the preparation of housing development appraisal with P-value 0.155, and that risk management is neither holistically implemented in the feasibility and viability appraisal process nor extensively taken into cognisance.Research limitations/implicationsThis paper reports the results of the practices among estate surveyors and valuers in regarding the risk associated in the preparation stages of the feasibility and viability appraisal processPractical implicationsThere are limited studies that suggest risk management factors in the appraisal reports for property development. Although previous studies have identified the risk factors, there is a lack of emphasis on management, which entails identification, assessment, monitoring and control. This study, therefore, recommends the incorporation of risk management into the feasibility and viability appraisal process implemented by estate surveyors and valuers. It is envisaged that the process will protect investors from the potential risk factors associated with investments in property development.Originality/valueThe study highlighted the need for practical or empirical research to be used to assess the significant risk factors that are needed to be reflected in the preparation stages of the feasibility and viability appraisal conduct of estate surveyors and valuers in Abuja, Nigeria.
Financial performance and corporate diversification strategies in professional football – evidence from the English Premier League
Authors: Holzmayer Florian , Schmidt Sascha L. 
Published: April 2020

PurposeProfessional football clubs have increasingly initiated two corporate diversification strategies to enfold growth opportunities besides traditional income sources: business diversification and international diversification. Empirical findings from management and sport management literature provide inconclusive evidence on these strategies' financial performance effects, necessitating further research. The purpose of this article is therefore to investigate how both corporate diversification strategies affect the financial performance of professional football clubs.Design/methodology/approachA 15-year panel data set of English Premier League (EPL) clubs is examined, many of which have employed corporate diversification strategies. Measures for related business diversification (RBD) and unrelated business diversification (UBD) as well as international diversification are established from management literature. Based on fixed effects regression models, their effects on clubs' revenues and profitability are then examined.FindingsU-shaped effects from RBD on revenues and profitability are found, but no effects from UBD. These findings empirically support the theoretically appealing superiority of RBD over UBD and, with increasing levels of RBD, over a focused strategy in management literature. With international diversification, an inverted U-shaped effect on revenues is identified.Research limitations/implicationsDespite focusing only on the EPL, these findings provide new evidence of non-linear financial performance effects from corporate diversification strategies adding to (sport) management literature and setting the stage for future research on these strategies in professional football.Practical implicationsThese findings have significant implications for club managers' strategic growth opportunities such as new business models or geographic markets.Originality/valueThis is the first study to empirically examine the financial effects of corporate diversification strategies in the football market context.
The Politics of Postcapitalism: Labour and our Digital Futures
Authors: Cruddas Jon , Pitts Frederick Harry 
Published: April 2020

AbstractThis article introduces the special issue on the politics of postcapitalism. Considering the theoretical foundations, empirical perspectives and political ramifications of claims made about a coming ‘post‐work’ or ‘postcapitalist’ society, it maps existing debates through a discussion of two key recent texts, Paul Mason’s Clear Bright Future and Aaron Bastani’s Fully Automated Luxury Communism. It first surveys how the relationship between labour market trends, technological change and wider political‐economic shifts is articulated in the postcapitalist literature. It then explores how concepts from Marx are deployed to depict social relations as a constraint on technological development and its utopian potentialities, leading to political demands for new class actors and electoral blocs centring on the new forms of economic and political activity associated with digital networks. It also considers the role of the state and how this theoretical and political approach envisions historical change, situating utopian visions of an incipient postcapitalist alternative to capitalism within the contemporary political context of authoritarian populism and challenges to liberal democracy. Finally, it explores the continuing relevance of humanism as a critical counterpoint to the social and philosophical agenda of present day ‘posthumanism’. It concludes that, in unfavourable political conditions, it would be strategically unwise to stake too much on an over‐optimistic approach to the unfolding future. This outlook, it is suggested, carries considerable risks and consequences for a contemporary left in search of a viable electoral coalition and route back to power.
Relationship between intestinal flora structure and metabolite analysis and immunotherapy efficacy in Chinese NSCLC patients
Authors: Song Peng , Yang Dongliang , Wang Hanping , Cui Xiaoxia , Si Xiaoyan , Zhang Xiaotong , Zhang Li 
Published: April 2020

BackgroundMany immune checkpoint inhibitors (ICIs) have been approved in China to treat non‐small cell lung cancer (NSCLC). However, in the long term, less than 20% of patients benefit from ICIs. To maximize the benefit for NSCLC patients, it is necessary to guide the choice of immunotherapy through biomarkers. Recent studies have shown that gut microbiota can affect tumor response to immunotherapy and might be a potential predictive biomarker. This study analyzed the relationship between intestinal flora structure and metabolomic characteristics in NSCLC and the efficacy of ICIs.MethodsProspective analysis of samples from 63 patients with advanced NSCLC who attended the Department of Respiratory Medicine of the Peking Union Medical College Hospital from March 2018 to June 2019, and were prescribed programmed cell death 1 (PD‐1) inhibitors, was carried out. The follow‐up deadline was 31 December 2019. Stool samples were collected from all patients before the start of immunotherapy. DNA was extracted from all samples and libraries were constructed. This was followed by sequencing using the Illumina sequencing platform, and results were studied using a biological information data analysis process. We divided the data into two groups based on progression‐free survival (PFS) ≥ six months and PFS < six months.ResultsThe median PFS was 7.0 months, not reaching the median overall survival (OS). We obtained 373.5 G of original sequencing data. The phyla Bacteroidetes, Firmicutes, Proteobacteria, and Actinobacteria accounted for most of the bacterial communities in the stool samples studied. Compared with the PFS < six‐month group, the patients in the PFS ≥ six‐month group had significantly higher β‐diversity in the intestinal microbiome at the baseline level. There were also differences in composition between the two groups. Samples in the PFS ≥ six‐month group were rich in Parabacteroides and Methanobrevibacter, while those in the PFS < six‐month group were rich in Veillonella, Selenomonadales, and Negativicutes. The KO, COG, and CAZy databases were used to study functional group protein families, yielding 390 (KO), 264 (COG), and 859 (CAZy) functional group abundances, with significant differences between the two groups. Bacterial metabolites analysis suggested significant differences in the metabolic potential of methanol and methane between the two groups.ConclusionsWe found a close correlation between intestinal microbiome β‐diversity and anti‐PD‐1 immunotherapy response in Chinese patients with advanced NSCLC. The intestinal flora composition, functional group protein family, and KEGG metabolism also differed between the two groups. Differences in pathways and flora metabolites were also noted.