bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hunger Affects Social Decisions in a Multi-Round Public Goods Game but Not a Single-Shot Ultimatum Game
Authors: Fraser Sam , Nettle Daniel 
Published: July 2020

Abstract
Objective
People have the intuition that hunger undermines social cooperation, but experimental tests of this have often produced null results. One possible explanation is that the experimental tasks used are not rich enough to capture the diverse pathways by which social cooperation can be sustained or break down in real life. We studied the effects of hunger on cooperation in two tasks of differential interaction richness.

Methods
We manipulated hunger by asking participants to eat, or refrain from eating, breakfast. Participants in experiment 1 (n = 106) played a one-shot Ultimatum Game. Participants in experiment 2 (n = 264) played twenty rounds of a Public Goods Game in the same groups of four, ten rounds with the possibility of punishing other group members, and ten without.

Results
In experiment 1, skipping breakfast had no significant effects on either amounts proposed or minimum acceptable offers. In experiment 2, there were multiple different significant effects of the manipulation. No-breakfast participants were more generous in the first round of the game without punishment, and in subsequent rounds, were more influenced by what other group members had done the round before. In the punishment game, no-breakfast participants were also less likely to punish their group-mates than breakfast participants. Consequently, the possibility of punishment was less effective in increasing group cooperation levels in no-breakfast groups.

Conclusion
Replicating earlier findings, we found a null effect of hunger on cooperation in a one-shot Ultimatum Game. However, in our richer Public Goods Game, the dynamics of cooperation differed with hunger, in subtle ways not simply classifiable as hungry participants being ‘more’ or ‘less’ cooperative overall.
Review of sustainable diets: are nutritional objectives and low-carbon-emission objectives compatible?
Authors: Doro Erica , Réquillart Vincent 
Published: July 2020

AbstractFood systems in developed countries face one major challenge, namely the promotion of diets that are both healthy and generate less greenhouse gas emissions (GHGE). In this article, we review papers evaluating the impact of a change in diets on both health and GHGE. We address the following questions: How big are the health and environmental impacts that could be induced by a switch to healthier diets? In monetary value, what is the relative importance of the health impact and the environmental impact? Is it possible to design an economic policy to increase global welfare that also takes into account the externalities on both health and the environment? Since the way the change in diet is modeled is a key issue, we classify papers according to the methodology used for simulating diet changes: ad hoc scenarios, optimized diets, and economic modeling. We find that it is possible to design economic policies that have positive impacts on both dimension. Because the substitutions/complementarities between food products are complex, it is not granted that a policy targeting one dimension will generate positive effects on the other dimensions. However, given the diversity of substitution and the complementarity possibilities between products, it is possible to design a policy that does improve both dimensions. A carbon-based tax policy that targets the products with a high greenhouse gas content (e.g., meat products) and reinvests the revenues collected with the tax to subsidize the consumption of fruit and vegetables, is likely to have positive effects on both dimensions.
Urban planning for physically disabled people’s needs with case studies
Authors: Shahraki Abdol Aziz 
Published: July 2020

AbstractThe aim of this study is to provide urban planning procedures tailored to the needs of disabled people. For this, it analyzes the problems of disabled people, especially physically disabled people, for living in Iran’s cities. It also analyses various planning and design characteristics of buildings in Iranian cities. Research methods of this paper are problem-oriented theoretical studies, case studies, a weighted sum method, and a Benchmarking technique. The methods assist to provide relevant standard indicators and a theoretical framework for the comparison of the cities to an optimal alternative. A case study strategy to gather data for certain comparisons and present a disabled-oriented model of urban planning has been performed. The weighted sum method dedicates quantitative scores and performs the comparison and judgment. Finally, this paper concludes that the cities in Iran are not appropriate to the physical and administrative needs of the disabled. This study finds that buildings in Iranian cities often lack the necessary standards for the needs of the disabled. The outcomes of this research concerning urban planning for disabled people will assist better disabled-oriented urban planning, design, and development everywhere in the world.
Collection of Post-treatment PRO Data in Oncology Clinical Trials
Authors: Lundy J. Jason , Coon Cheryl D. , Fu An-Chen , Pawar Vivek 
Published: July 2020

AbstractAs patient-reported outcome (PRO) measures are being included more frequently in oncology clinical trials, regulatory and health technology assessment agencies have begun to request long-term, post-treatment PRO data to supplement traditional survival/progression endpoints. These data may be collected as part of cohort extension or registry studies to describe long-term outcomes of study participants after concluding their cancer treatment. While post-treatment PRO data may be expected to satisfy regulatory and payer expectations, significant practical barriers exist for the efficient incorporation of these data into oncology clinical trials, such as subject attrition, protocol deviations, and treatment crossover. The incorporation of post-treatment PRO assessments is a resource-intensive task requiring clear objectives for how the data will be analyzed and interpreted by both sponsors and regulators. Incorporating PRO data collection via electronic modalities (e.g., smartphone, web) may be a less expensive and more feasible option for incorporating long-term follow-up, reducing the frequency of manual study staff follow-up and expensive clinic visits. It is essential to include well-defined estimands for the statistical analysis, as well as to document limitations associated with the long-term follow-up data-collection approach. Analytical techniques will likely rely on descriptive and model-based statistics, and conclusions about treatment differences will likely be limited to preliminary findings of effectiveness (instead of efficacy). Finally, communications with health authorities and regulatory agencies regarding the LTFU study design and analysis should occur as early as possible to ensure that the PRO data to be collected offer an opportunity to properly evaluate the research question(s) of interest.
Love in the Time of COVID-19: Sexual Function and Quality of Life Analysis During the Social Distancing Measures in a Group of Italian Reproductive-Age Women
Authors: Schiavi Michele Carlo , Spina Vincenzo , Zullo Marzio Angelo , Colagiovanni Vanessa , Luffarelli Paolo , Rago Rocco , Palazzetti Pierluigi 
Published: July 2020

Abstract

Background
The beginning of 2020 was characterized by the COVID-19 pandemic. The world governments have adopted restrictive measures to reduce the spread of infection. These measures could affect the sexual function and quality of life of women living with their partner.

Aim
The aim is to assess the impact of the social distancing measures caused by the COVID-19 pandemic on sexual function and quality of life of noninfected reproductive-age women, living with their sexual partner.

Methods
Observational analysis on sexually active women, living with their partner, and without COVID-19 infection was performed. The population previously answered FSFI, FSDS, and SF-36 questionnaires. 4 weeks after the introduction of the restrictive measures, these women were invited to complete the same questionnaires by e-mail for an evaluation during the COVID-19 outbreak.

Main Outcome Measures
The primary endpoint was the assessment of the women's sex function change during the social restriction period, by analyzing the FSFI and FSDS questionnaires. The secondary endpoint was the evaluation of the impact on the quality of life calculated by the SF-36 questionnaire.

Results
89 patients were considered. The median age was 39 (28–50) years. Mean sexual intercourses/month decreased from 6.3 ± 1.9 to 2.3 ± 1.8, mean difference: −3.9 ± 1.2. FSFI decreased significantly (29.2 ± 4.2 vs 19.2 ± 3.3, mean difference: −9.7 ± 2.6) and FSDS increased significantly (9.3 ± 5.5 vs 20.1 ± 5.2, mean difference: 10.8 ± 3.4). The SF-36 showed a significant change from 82.2 ± 10.2 to 64.2 ± 11.8 4 weeks after the introduction of the restrictive measures; mean difference: −17.8 ± 6.7. The univariable analysis identified working outside the home, university educational level, and parity ≥1 as predictive factors of lower FSFI. In multivariable analysis, working outside the home and combination of working outside the home + university educational level + parity ≥1 were the independent factors of a lower FSFI.

Clinical Implication
The negative impact of the COVID-19 epidemic period on sexual function and quality of life in women shows how acute stress might affect the psychological state. Thus, psychological or sexual support could be useful.

Strengths and Limitations
To our knowledge, this study is the first that analyzes the change in sexual activity in women during the COVID-19 outbreak period. The limitations were the low number of the analyzed participants, psychological tests were not included, and no data were collected on masturbation, self-heroism, solitary, and nonpenetrative sex.

Conclusion
The COVID-19 epidemic and the restrictive social distancing measures have negatively influenced the sexual function and quality of life in not-infected reproductive-age women who live with their sexual partners.
Hegel on the Normativity of Animal Life
Authors: Mills Nicolás García 
Published: July 2020

AbstractMy aim in this paper is to show that and how animal organisms are appropriate subjects of normative evaluation, on Hegel's view. I contrast my reading with the interpretive positions of Sebastian Rand and Mark Alznauer. I disagree with Rand and agree with Alznauer that animal organisms are normatively evaluable for Hegel. I substantiate my disagreement with Rand, and supplement Alznauer's interpretation, by spelling out the role that the ‘generic process’ or ‘genus process [Gattungsprozess]’ plays within Hegel's account of animal organisms and their normative evaluability. In the course of my discussion, I highlight the main differences that Hegel purports to identify between animal and vegetable organisms and suggest that the upshot of those differences is that some but not all plants are normatively evaluable, by his lights. I also situate Hegel's discussion of theGattungsprozesswithin the debate on biological functions in the philosophy of biology over the last few decades.
The Reputational Costs and Ethical Implications of Coercive Limited Air Strikes: The Fallacy of the Middle-Ground Approach
Authors: Lupton Danielle L. 
Published: July 2020

AbstractLimited air strikes present an attractive “middle-ground approach” for policymakers, as they are less costly to coercers than deploying troops on the ground. Policymakers believe that threatening and employing limited air strikes signal their resolve to targets. In this essay, as part of the roundtable on “The Ethics of Limited Strikes,” I debunk this fallacy and explain how the same factors that make limited air strikes attractive to coercers are also those that undermine their efficacy as a coercive tool of foreign policy. The limited nature of these air strikes undermines the ability of coercers to effectively signal their resolve. In turn, coercive threats of limited air strikes are less likely to be credible, creating a vicious cycle: policymakers threaten to employ air strikes because they are less costly but then often need to follow through on those threats as target states fail to acquiesce to their demands, precisely because limited air strikes are less costly for the coercer. Limited air strikes, therefore, can actually be a source of conflict escalation and lead policymakers to engage in military action that they would prefer to avoid. I further explain why failing to follow through on such coercive threats can undermine a leader's reputation for resolve and lead to future crisis escalation. Finally, I discuss what this quagmire means for the ethics of the threat and the use of air strikes, particularly for the principles of right intention, likelihood of success, and probability of escalation.
Lengthening the Shadow of International Law
Authors: Fazal Tanisha M. 
Published: July 2020

AbstractWhat will be the consequences of the criminalization of aggression? In 2010, the International Criminal Court made aggression a crime for which individuals can be prosecuted. But questions around what constitutes aggression, who decides, and, most important, how effective this legal change will be in reducing the incidence of war remain. This essay considers these questions in light of two recent books on the criminalization of aggression: Noah Weisbord'sThe Crime of Aggression: The Quest for Justice in an Age of Drones, Cyberattacks, Insurgents, and Autocratsand Tom Dannenbaum'sThe Crime of Aggression, Humanity, and the Soldier. While the authors argue in favor of the efficacy of the criminalization of aggression as a means to reduce future war, it is also likely that the criminalization of aggression will reshape war in potentially profound ways.
A Problem from Washington: Samantha Power Enters the Foreign Policy Bureaucracy
Authors: Barnett Michael 
Published: July 2020

AbstractIn her new memoir, The Education of an Idealist, Samantha Power reflects on her eight years in the Obama administration. Although she claims that the experience did little to change her views, there is a considerable disjuncture between her point of view in her award-winning earlier book “A Problem from Hell,” in which she criticizes U.S. officials for not doing the right thing, and her point of view in The Education of an Idealist, in which she defends indifference of U.S. officials under somewhat similar circumstances during the Obama years. The author of Problem could not have written Education, and the author of Education could not have written Problem. What does this tell us about the possibility for ethics in foreign policy?
Epicotyl morphophysiological dormancy and storage behaviour of seeds of Strychnos nux-vomica, Strychnos potatorum and Strychnos benthamii (Loganiaceae)
Authors: Muthuthanthirige Deshika L. , Wijetunga W.M.G. Asanga S.T.B. , Gehan Jayasuriya K.M.G. 
Published: July 2020

AbstractWe hypothesized that Strychnos nux-vomica and Strychnos potatorum in seasonal tropical ecosystems have dormant desiccation-tolerant seeds, while those of Strychnos benthamii growing in aseasonal wet habitats have non-dormant desiccation-sensitive seeds. Germination, imbibition, the effect of gibberellic acid on germination and changes in the embryo to seed length ratio (E:S) during incubation were determined for the three species. Seed storage behaviour was identified with the hundred seed test. Time taken for epicotyl emergence was recorded. Radicle emergence of S. nux-vomica, S. potatorum and S. benthamii at 25°C under light/dark conditions (12/12 h) was completed within 76, 49 and 11 d, respectively. S. nux-vomica and S. potatorum seeds incubated on GA3 germinated to a higher percentage than non-treated seeds. E:S of S. nux-vomica, S. potatorum and S. benthamii had increased by 38.2, 34.5 and 25.5%, respectively, at radicle emergence. Shoot emergence of S. nux-vomica, S. potatorum and S. benthamii was observed after 76, 74 and 45 d from radicle emergence, respectively. Thus, it can be concluded that the seeds of all three species have epicotyl morphophysiological dormancy. Hundred seed tests revealed that S. nux-vomica and S. potatorum seeds were desiccation-tolerant, while those of S. benthamii were desiccation-sensitive. Our study showed that species from seasonal habitats (S. nux-vomica and S. potatorum) have desiccation-tolerant morphophysiologically dormant seeds, while those from an aseasonal habitat (S. benthamii) have desiccation-sensitive morphophysiologically dormant seeds, revealing that their dormancy and desiccation tolerance behaviour are adaptations to their environment.
Maternal ageing causes changes in DNA methylation and gene expression profiles in mouse oocytes
Authors: Hou Guanmei , Sun Qing-Yuan 
Published: July 2020

SummaryAlthough it is well known that maternal ageing causes reduced oocyte quality and fertility, little information is known about its effect on germ cell epigenetics. In the present study, we compared the gene expression and DNA methylation profiles in germinal vesicle oocytes from young (8-week-old) and aged (18-month-old) mice using single-cell RNA-sequencing and single-cell whole-genome DNA methylation sequencing. We found significant differences in the data from the two groups. Oocytes from aged mice showed significant changes in the expression of some metabolism-related genes, such as mitochondria-associated genes, that was in line with our expectations. Expression of some genes associated with reproduction also showed significant differences. DNA methylation levels were also changed in oocytes from aged mice. The two groups had significant gaps in hypermethylation and hypomethylation levels on each chromosome. These data provide useful information for further understanding the mechanisms of oocyte ageing.
Evaluation of nutritional quality of biscuits and sweet snacks sold on the Italian market: the Food Labelling of Italian Products (FLIP) study
Authors: Dall’Asta M , Rosi A , Angelino D , Pellegrini N , Martini D 
Published: July 2020

AbstractObjective:The present study aimed at surveying the nutritional quality of prepacked biscuits and sweet snacks sold on the Italian market, and at identifying whether the product type and other information reported on the pack could discriminate the overall quality of products analysed.Design:Data on energy, nutrient and salt content of the products from two different categories of prepacked sweet cereal products (i.e. biscuits and sweet snacks) were collected from thirteen retailers present on the Italian market. Based on the product type, nutrition and health claim (NHC) and gluten-free (GF) declaration, a comparison of nutrient profile within each category was performed.Setting:This work is part of the Food Labelling of Italian Products (FLIP) study that aims at systematically investigating the overall quality of the prepacked foods sold on the Italian market.Results:A total of 1290 products were analysed (63 % biscuits and 37 % sweet snacks). After comparing different product types within each category, a high intra-type product variability was evidenced, which was more pronounced for biscuits. Overall, NHC-carrying products seemed to have a better nutrition profile than those without claims, except for salt content. Conversely, a comparison between GF and gluten-containing products did not show consistent results within the two categories analysed.Conclusions:Due to the high intra-type variability within each category, the different characteristics and regulated information reported on the pack do not seem to be a clear marker of the overall nutritional quality of biscuits and snacks.
High coenzyme Q10 plasma levels improve stress and damage markers in professional soccer players during competition
Authors: Sánchez-Cuesta Ana , Cortés-Rodríguez Ana Belén , Navas-Enamorado Ignacio , Lekue José Antonio , Viar Toscana , Axpe Martín , Navas Plácido , López-Lluch Guillermo 
Published: July 2020

Abstract. Ubiquinol, the reduced form of Coenzyme Q10 (CoQ10), is a key factor in bioenergetics and antioxidant protection. During competition, professional soccer players suffer from considerable physical stress causing high risk of muscle damage. For athletes, supplementation with several antioxidants, including CoQ10, is widely recommended to avoid oxidative stress and muscle damage. We performed an observational study of plasma parameters associated with CoQ10 levels in professional soccer players of the Spanish First League team Athletic Club de Bilbao over two consecutive seasons (n = 24–25) in order determine their relationship with damage, stress and performance during competition. We analyzed three different moments of the competition: preterm, initial phase and mid phase. Metabolites and factors related with stress (testosterone/cortisol) and muscle damage (creatine kinase) were determined. Physical activity during matches was analyzed over the 2015/16 season in those players participating in complete matches. In the mid phase of competition, CoQ10 levels were higher in 2015/16 (906.8 ± 307.9 vs. 584.3 ± 196.3 pmol/mL, p = 0.0006) High levels of CoQ10 in the hardest phase of competition were associated with a reduction in the levels of the muscle-damage marker creatine kinase (Pearsons’ correlation coefficient (r) = − 0.460, p = 0.00168) and a trend for the stress marker cortisol (r = −0.252, p = 0.150). Plasma ubiquinol was also associated with better kidney function (r = −0.287, p = 0.0443 for uric acid). Furthermore, high CoQ10 levels were associated with higher muscle performance during matches. Our results suggest that high levels of plasma CoQ10 can prevent muscle damage, improve kidney function and are associated with higher performance in professional soccer players during competition.
Calibrated Simulation of the Long‐Term Average Surficial Groundwater System and Derived Spatial Distributions of its Characteristics for the Contiguous United States
Authors: Zell Wesley O. , Sanford Ward E. 
Published: July 2020

AbstractWhile the physical processes governing groundwater flow are well understood, and the computational resources now exist for solving the governing equations in three dimensions over continental‐scale domains, there remains substantial uncertainty about the subsurface distribution of the properties that control groundwater flow and transport for much of the contiguous United States (CONUS). The transmissivity of the shallow subsurface is a key parameter for the simulation of water table position, shallow groundwater flow, and base‐flow discharge, but is not well‐characterized at large regional to continental scales. We used a process‐based inversion of CONUS‐extent groundwater information to generate national data sets of (a) the transmissivity of the shallow groundwater system, (b) the depth to the water table, (c) groundwater discharge as base‐flow, and (d) long‐term average water content in the unsaturated zone. CONUS‐extent coverage was developed in the form of 75 subdomain models, with the spatial distribution of long‐term average transmissivity for each subdomain model calibrated against water‐levels derived from U.S. Geological Survey (USGS) observation wells, NHDPlusV2 first‐order perennial streams, and National Wetlands Inventory (NWI) freshwater wetlands. Estimated transmissivities were lower in the western CONUS than the eastern CONUS, and across the CONUS both transmissivity and depth to water correlate with recharge, elevation, and topographic slope. These generated data sets provide spatially distributed, long‐term average estimates of subsurface properties and hydrological states that we anticipate will complement other environmental modeling efforts as explanatory variables, boundary conditions, or transport pathways.