bluuebunny/crossref_metadata_2025_split huggingface dataset:
Excited State Proton Transfer of Quinone Cyanine 9: Implications on the Origin of Super‐Photoacidity
Authors: Lee Changmin , Chung Seyoung , Song Hayoung , Rhee Young Min , Lee Eunsung , Joo Taiha 
Published: November 2020

AbstractQuinone cyanine 9 (QCy9) is one of the strongest photoacids known to date. The origin of “super”‐photoacidity was investigated via time‐resolved fluorescence (TF) with high time resolution to accurately resolve the ultrafast dynamics of the excited‐state proton transfer (ESPT) to solvent. The ESPT of QCy9 in water is found to proceed fully by two ultrafast time constants of 40 fs (65 %) and 200 fs (35 %). More importantly, the initially created base form of QCy9 in the excited state undergoes a significant dynamic red shift of over 2700 cm−1 by solvation. We suggest that the entirely ultrafast reaction rate and the massive solvation of the conjugate base could make QCy9 a particularly strong photoacid. Quantum chemical calculations show that structural diversity leads to the nonexponential behavior of the ESPT dynamics.
Remote Training of SRL Users and Staff in a Global Pandemic
Authors: Daniels Kathleen , Conway Alexis , Gardner Rui , Martinez Lola , Price Kylie M. , Schneider Sarah , Sheridan Rachael , Srivastava Jane , Thornton Sherry 
Published: November 2020

AbstractThe impact of the COVID‐19 pandemic on training and Shared Resource Laboratory (SRL) operations such as staffing, facility access, and social distancing, has affected facilities around the globe to different degrees based on restrictions set by various geographical and institutional settings. With these restrictions come unique challenges regarding user and staff training and education, for both theory and practice. Most notably, limitations in facility access, occupancy, staffing availability, network restrictions and trainee engagement call for innovative solutions for training when traditional in‐person options are not feasible. Through the use of remote access tools and prerecorded educational and training materials, SRLs are able to overcome these obstacles. Here, we focus on readily available technologies and general guidelines that SRLs in different environments can use for remote cytometry training and education, while highlighting key obstacles that still remain. Although SRLs may face initial struggles in transitioning trainings to a virtual format, remote technologies provide unique opportunities to advance current training programs. © 2020 International Society for Advancement of Cytometry
Warthin‐Finkeldey giant cells—A useful clue for the cytodiagnosis of Kimura disease: A report of three cases
Authors: Kothari Kanchan , Agnihotri Mona , Rojekar Amey , Waghmare Tejaswini , Kolhe Ashvini 
Published: November 2020

AbstractKimura disease (KD) is a rare, idiopathic chronic inflammatory disorder that usually presents as unilateral painless lymphadenopathy or soft tissue swelling of the head and neck region in young Asian males. The disease lacks pathognomonic clinical and cytomorphological features and can be mistaken for many reactive and malignant conditions. We report three cases of KD presenting as bilateral swelling of the head and neck region, and describe the cytomorphological features of each. In the correct clinical setting, a polymorphous lymphoid aspirate with eosinophils and Warthin‐Finkeldey giant cells should raise a suspicion of KD and prompt further work up.
A review of conspecific attraction for habitat selection across taxa
Authors: Buxton Valerie L. , Enos Janice K. , Sperry Jinelle H. , Ward Michael P. 
Published: November 2020

AbstractMany species across taxa select habitat based on conspecific presence, known as conspecific attraction. Studies that document conspecific attraction typically provide social information (i.e., cues that indicate the presence of a given species) and then determine if a given species is more likely to settle at locations where the social information is provided compared to those locations that do not. Although the number of studies examining conspecific attraction has grown in recent years, a comprehensive review has not yet been undertaken. Here, we conducted a review of the literature and found 151 studies investigating conspecific attraction across eight taxa. We found that conspecific attraction is widespread with between 80% and 100% of studies, depending on taxa, documenting positive associations between habitat selection and the presence of conspecific cues. Conspecific attraction has been documented more frequently in bird and fish species with less attention given to invertebrate and mammal species. We use the patterns we found to (a) provide an overview of the current state of research on conspecific attraction and (b) discuss how important factors, such as cue characteristics and life history traits, may play a role in shaping conspecific attraction patterns within and across taxa.
Growth, stress, and acclimation responses to fluctuating temperatures in field and domesticated populations of Manduca sexta
Authors: Kingsolver Joel G. , Moore M. Elizabeth , Hill Christina A. , Augustine Kate E. 
Published: November 2020

AbstractDiurnal fluctuations in temperature are ubiquitous in terrestrial environments, and insects and other ectotherms have evolved to tolerate or acclimate to such fluctuations. Few studies have examined whether ectotherms acclimate to diurnal temperature fluctuations, or how natural and domesticated populations differ in their responses to diurnal fluctuations. We examine how diurnally fluctuating temperatures during development affect growth, acclimation, and stress responses for two populations of Manduca sexta: a field population that typically experiences wide variation in mean and fluctuations in temperature, and a laboratory population that has been domesticated in nearly constant temperatures for more than 300 generations. Laboratory experiments showed that diurnal fluctuations throughout larval development reduced pupal mass for the laboratory but not the field population. The differing effects of diurnal fluctuations were greatest at higher mean temperature (30°C): Here diurnal fluctuations reduced pupal mass and increased pupal development time for the laboratory population, but had little effect for the field population. We also evaluated how mean and fluctuations in temperature during early larval development affected growth rate during the final larval instar as a function of test temperature. At an intermediate (25°C) mean temperature, both the laboratory and field population showed a positive acclimation response to diurnal fluctuations, in which subsequent growth rate was significantly higher at most test temperatures. In contrast at higher mean temperature (30°C), diurnal fluctuations significantly reduced subsequent growth rate at most test temperatures for the laboratory population, but not for the field population. These results suggest that during domestication in constant temperatures, the laboratory population has lost the capacity to tolerate or acclimate to high and fluctuating temperatures. Population differences in acclimation capacity in response to temperature fluctuations have not been previously demonstrated, but they may be important for understanding the evolution of reaction norms and performance curves.
Preconcentration and Successful Selective Detection of Traces of Diclofenac in Water using a Nanostructured Modified Carbon Paste Electrode
Authors: Amra Siham , Bourouina Mustapha , Bourouina Bacha Saliha , Hauchard Didier 
Published: November 2020

AbstractA highly sensitive, simple and low cost sensor for the quantification of the diclofenac has been constructed. This sensor consists of a carbon paste nano‐structured by Multi‐Walled Carbon Nanotubes (G‐MWCNT)‐CPE. Scanning electron microscopy (SEM) and voltammetry technique were used to characterize the electrode material and to determine the analytical performances of the sensor in comparison with those obtained at a G‐CPE. The electrochemical oxidation of diclofenac on both G‐CPE and (G‐MWCNT)‐CPE electrodes is mainly controlled by adsorption, presenting a maximum peak current intensity in H2SO4 0.5 mol L−1. The carbon nanotubes, as well as they provide higher conductivity of the paste, act as spacers between the flake graphite particles and avoid their stacking in order to make the surface of graphite particles more accessible to DCF adsorption. The voltammetric measurements of diclofenac on (G‐MWCNT)‐CPE provide a large quantification range from 0.02 to 1 μmol L−1, a detection limit of 0.004 μmol L−1 and quantification limit of 0.014 μmol L−1 under the optimized operating conditions (H2SO4, 0.25 M+KCl 0.25 M, scan rate of 30 mV s−1, preconcentration time 18 min. and MWNTC% (30 %)). The (G‐MWCNT)‐CPE sensor was successfully applied to natural water samples, just acidified with sulfuric acid (pH<1). These samples were doped with diclofenac in sub‐micromolar range and the developed method was validated with excellent recoveries (within a maximum of 3 % difference from 100 %) for all samples indicating no interference effects of the water matrix.
Facile Nonenzymatic Glucose Electrode Composed of Commercial CuO Powder and Ionic Liquid Binder
Authors: Lo Nai‐Chang , Hsu Wei‐Shan , Chen Yi‐Ting , Sun I‐Wen , Chen Po‐Yu 
Published: November 2020

AbstractCommercially available micro‐sized CuO powder was dispersed in the mixture of ethanol and protonated betaine bis((trifluoromethyl)sulfonyl)amide ([Hbet][TFSA]), a hydrophobic amide‐type protic ionic liquid (IL), to prepare a composite paste for the modification of screen‐printed carbon electrode (SPCE) via spin‐coating. The fabricated SPCE\CuO−IL composite‐based electrode showed a comparable activity as that of the nanonized metal‐oxide based electrodes towards the electrochemical oxidation of glucose in alkaline solutions. Hydrodynamic chronoamperometry tests performed at +0.55 V showed a linear dynamic response of the electrode over the concentration range of 1 μM–2.8 mM with a sensor‐sensitivity of 0.16 μA μM−1 in 0.1 M NaOH. The data also showed a linear dynamic response over the concentration range of 1 μM–4.6 mM with a sensor‐sensitivity of 0.10 μA μM−1 in 0.1 M NaOH with 0.1 M NaCl, indicating that the major interferant Cl− had negligible effects on glucose detection . Ascorbic acid (AA) (in the physiological level) and ethanol also did not interfere with the detection. Detection of glucose in real samples showed the recovery ratios higher than 95 %. This study has clearly demonstrated that commercial CuO powder without nanostructure can provide sufficient reactivity to the electrocatalytic oxidation of glucose by using IL as the organic binder. Facile preparation of the micro‐sized metal oxide‐modified electrodes can be accordingly pursued.
The effect of body mass index on hippocampal morphology and memory performance in late childhood and adolescence
Authors: Lynch Kirsten M. , Page Kathleen A. , Shi Yonggang , Xiang Anny H. , Toga Arthur W. , Clark Kristi A. 
Published: November 2020

AbstractChildhood obesity is associated with negative physiological and cognitive health outcomes. The hippocampus is a diverse subcortical structure involved in learned feeding behaviors and energy regulation, and research has shown that the hippocampus is vulnerable to the effects of excess adiposity. Previous studies have demonstrated reduced hippocampal volume in overweight and obese children; however, it is unclear if certain subregions are selectively affected. The purpose of this study was to determine how excess body weight influences regional hippocampal surface morphology and memory performance in a large cross‐sectional cohort of 588 children and adolescents between 8.33 and 19.92 years of age using body mass index expressed as a percentage of the 95th percentile cutoff (%BMIp95). We demonstrate %BMIp95 is associated with reduced radial thickness in the superior anterior region of the left hippocampus, and this relationship is predominantly driven by children younger than 14 years. We also found %BMIp95 was associated with worse performance on a spatial episodic memory task and this relationship was partially mediated by the radial thickness of the significant shape cluster. These results demonstrate the differential influence of excess body weight on regional hippocampal structure and hippocampal‐dependent behavior in children and adolescents.
Stock market dynamics and the relative importance of domestic, foreign, and common shocks
Authors: Ademmer Martin , Horn Wolfram , Quast Josefine 
Published: November 2020

AbstractWe quantify the contemporaneous relationships among stock markets in the euro area, the United States, and a group of emerging economies over the period from 2008 to 2017. Exploiting the heteroskedasticity in the stock market data, we identify shocks that originated in the respective domestic markets and shocks that are common to all markets. Our results underline the leading role of the United States in international equity markets, but also point to the importance of indirect spillovers for all economies. Variance decompositions show that while domestic shocks explain the bigger part of the variation in each stock market, a substantial part of the variation in the euro area and the emerging economies can be attributed to foreign shocks. A comparison with a sample covering the pre‐crisis period from 1999 to 2007 suggests a strengthening of the linkages among global stock markets in recent years. In particular, the spillovers from advanced to emerging economies have become more pronounced.
The role of emotion dysregulation in the association between posttraumatic stress disorder symptoms and suicidal thoughts and behaviors among veterans
Authors: Raudales Alexa M. , Weiss Nicole H. , Dixon‐Gordon Katherine L. , Contractor Ateka A. , Schatten Heather T. 
Published: November 2020

AbstractObjectiveAlthough research has established a link between posttraumatic stress disorder (PTSD) symptoms and suicidal thoughts and behaviors (STBs), little is known about factors that may accentuate this relation. This study evaluated the influences of negative and positive emotion dysregulation on the association between PTSD symptoms and STBs among veterans.MethodsFour‐hundred and sixty‐five trauma‐exposed military veterans in the community (M
age = 38.00, 71.4% male, 69.5% White) completed online questionnaires.ResultsNegative emotion dysregulation did not moderate the relation between PTSD symptoms and STBs. Results showed significant interactive effects of PTSD symptoms and positive emotion dysregulation on STBs, such that PTSD symptoms were more strongly related to STBs at high (vs. low) levels of positive emotion dysregulation. This effect was sustained across domains of positive emotion dysregulation.ConclusionsFindings suggest a potential need to consider positive emotion dysregulation in the assessment and treatment of STBs among veterans with PTSD symptoms.
Psychological inflexibility processes and nonsuicidal self‐injury: Concurrent and prospective associations
Authors: Callahan Katie E. , Stori Shane A. , Donahue John J. 
Published: November 2020

AbstractObjectiveThe aim of this study was to examine concurrent and 3‐month prospective associations between a multidimensional measure of psychological inflexibility and nonsuicidal self‐injury (NSSI) among participants with a self‐harm history.MethodParticipants completed measures of NSSI, psychological inflexibility, negative urgency, and depression at baseline (N = 106, Mage = 34.70, SD = 9.43, 66% women), and were again assessed at follow‐up (N = 86).ResultsParticipants currently engaging in NSSI reported significantly higher psychological inflexibility as compared to those who have ceased NSSI. After controlling for covariates, psychological inflexibility was concurrently associated with NSSI recency and longitudinally predicted perceived likelihood of future NSSI. Psychological inflexibility was not associated with new NSSI acts after including baseline covariates. Finally, psychological inflexibility subscales demonstrated differential relationships with various NSSI functions.ConclusionResults highlight the psychological inflexibility model's utility in understanding NSSI and have implications for future research that may inform clinical practice.
Preparing for invasion: Assessing risk of infection by chytrid fungi in southeastern plethodontid salamanders
Authors: Friday Brenna , Holzheuser Chace , Lips Karen R. , Longo Ana V. 
Published: November 2020

AbstractUnderstanding the responses of naïve communities to the invasion of multihost pathogens requires accurate estimates of susceptibility across taxa. In the Americas, the likely emergence of a second amphibian pathogenic fungus (Batrachochytrium salamandrivorans, Bsal) calls for new ways of prioritizing disease mitigation among species due to the high diversity of naïve hosts with priorB. dendrobatidis(Bd) infections. Here, we applied the concept of pathogenic potential to quantify the virulence of chytrid fungi on naïve amphibians and evaluate species for conservation efforts in the event of an outbreak. The benefit of this measure is that it combines and summarizes the variation in disease effects into a single numerical index, allowing for comparisons across species, populations or groups of individuals that may inherently exhibit differences in susceptibility. As a proof of concept, we obtained standardized responses of disease severity by performing experimental infections withBsalon five plethodontid salamanders from southeastern United States. Four out of five species carried natural infections ofBdat the start of the experiments. We showed thatBsalexhibited its highest value of pathogenic potential in a species that is already declining (Desmognathus auriculatus). We find that this index provides additional information beyond the standard measures of disease prevalence, intensity, and mortality, because it leveraged these disease parameters within each categorical group. Scientists and practitioners could use this measure to justify research, funding, trade, or conservation measures.
Family communication of genetic test results among women with inherited breast cancer genes
Authors: Cragun Deborah , Weidner Anne , Tezak Ann , Clouse Kate , Pal Tuya 
Published: November 2020

AbstractIdentification of inherited breast cancer may guide care. These benefits can be amplified through communication of genetic test results with at‐risk family members and subsequent family testing (FT). Females with a pathogenic/likely pathogenic (P/LP) variant in BRCA1/2, PALB2, CHEK2, and/or ATM were surveyed about family communication (FC) of genetic test results and FT. Comparisons were made across genes. The 235 participants with P/LP variants (186 BRCA1/2, 28 PALB2, 15 CHEK2, and 6 ATM) had a median age of 54 and most were non‐Hispanic whites (89%) with a prior breast cancer diagnosis (61%). When controlling for other variables, FC was higher among younger participants (p<.0001), those with high FC self‐efficacy (p=.019), and those with P/LP variants in BRCA1/2 compared to PALB2 (p =.040) and ATM/CHEK2 (p =.032). Higher rates of FC and FT were also observed among female relatives and relatives of closer kinship. Overall 94% of participants would find one or more resources helpful with FC and 70% reported using FC resources when telling family members about their genetic test result. The three most commonly used resources included the following: (a) a family sharing letter (38%); (b) printed materials (30%); and (c) web‐based information (23%). Among the 86% who spoke with a genetic counselor (GC), 93% were given at least one FC resource and the three most common resources GCs provided to participants overlapped with the resources participants would find helpful and those that were used. Our results suggest lower FC and FT rates among women with P/LP variants in genes other than BRCA1/2, the reasons for which should be evaluated in future studies. As more data to refine cancer risks and management are generated across these other inherited breast cancer genes, strategies to improve FC and FT are needed to amplify the benefits of genetic testing.
Impact of time‐to‐surgery on outcomes of patients undergoing curative‐intent liver resection for BCLC‐0, A and B hepatocellular carcinoma
Authors: Tsilimigras Diamantis I. , Hyer J. Madison , Diaz Adrian , Moris Demetrios , Bagante Fabio , Ratti Francesca , Marques Hugo P. , Soubrane Olivier , Lam Vincent , Poultsides George A. , Popescu Irinel , Alexandrescu Sorin , Martel Guillaume , Workneh Aklile , Guglielmi Alfredo , Hugh Tom , Aldrighetti Luca , Endo Itaru , Pawlik Timothy M. 
Published: November 2020

AbstractBackgroundThe impact of a prolonged time‐to‐surgery (TTS) among patients with resectable hepatocellular carcinoma (HCC) is not well defined.MethodsPatients who underwent curative‐intent hepatectomy for BCLC‐0, A and B HCC between 2000 and 2017 were identified using a multi‐institutional database. The impact of prolonged TTS on overall survival (OS) and disease‐free survival (DFS) was examined.ResultsAmong 775 patients who underwent resection for HCC, 537 (69.3%) had early surgery (TTS < 90 days) and 238 (30.7%) patients had a delayed surgery (TTS ≥ 90 days). Patient‐ and tumor‐related characteristics were similar between the two groups except for a higher proportion of patients undergoing major liver resection in the early surgery group (31.3% vs. 23.8%, p = .04). The percentage of patients with delayed surgery varied from 8.8% to 59.1% among different centers (p < .001). Patients with TTS < 90 days had similar 5‐year OS (63.7% vs. 64.9; p = .79) and 5‐year DFS (33.5% vs. 42.4; p = .20) with that of patients with TTS ≥ 90 days. On multivariable analysis, delayed surgery was not associated with neither worse OS (BCLC‐0/A: adjusted hazards ratio [aHR] = 0.90; 95% confidence interval [CI]: 0.65–1.25 and BCLC‐B: aHR = 0.72; 95%CI: 0.30–1.74) nor DFS (BCLC‐0/A: aHR = 0.78; 95%CI: 0.60–1.01 and BCLC‐B: aHR = 0.67; 95% CI: 0.36–1.25).ConclusionApproximately one in three patients diagnosed with resectable HCC had a prolonged TTS. Delayed surgery was not associated with worse outcomes among patients with resectable HCC.