bluuebunny/crossref_metadata_2025_split huggingface dataset:
Übersetzung der Standardisierten Terminologie für EEG
bei Intensivstationspatienten der American Clinical Neurophysiological Society:
Version 2012 (Hirsch et al. American Clinical Neurophysiology Society’s
Standardized Critical Care EEG Terminology: 2012 version. J Clin Neurophysiol
2013; 30: 1–27)
Authors: Rémi J. , Noachtar S. 
Published: December 2020

Zusammenfassung2012 erarbeitete eine EEG-Expertengruppe der American Clinical Neurophysiology
Society (ACNS) eine standardisierte Terminologie für EEG Muster, die bei
kritisch kranken Patienten häufig sind. Bis dahin existierte keine
einheitlich akzeptierte Nomenklatur für diese EEG Muster, wie zum
Beispiel periodische Entladungen, fluktuierende rhythmische Muster und
Kombinationen der beiden. Dabei bestand auch kein Konsens welche Muster mit
welchem neuronalen Schaden korrelieren, welche Muster behandelt werden
müssen oder wie aggressiv die Behandlung erfolgen sollte. Um diese
Fragen anzugehen entwickelte diese Gruppe eine standardisierte Terminologie
zunächst für den wissenschaftlichen Einsatz. Ziel war es die
Kommunikation zu erleichtern, indem Begriffe mit klinischer Konnotation
vermieden wurden und um damit multizentrische Forschung zu erleichtern.
Empfehlungen zur Durchführung einer Bronchoskopie in Zeiten der COVID-19-Pandemie: Update 12/2020
Authors: Darwiche K. , Ross B. , Gesierich W. , Petermann C. , Huebner R.-H. , Grah C. , Gompelmann D. , Hetzel J. , Holland A. , Eisenmann S. , Stanzel F. , Kempa A. , Conrad K. , Hagmeyer L. , Eberhardt R. 
Published: December 2020

ZusammenfassungDie Pandemie ausgelöst durch SARS-CoV-19 geht weltweit unverändert mit einer bedeutsamen Morbidität und Mortalität einher, sodass Schutzmaßnahmen zur Verhinderung der Transmission des Virus weiterhin notwendig sind. Mitarbeiter im Gesundheitswesen sind einem höheren Risiko ausgesetzt, und dies gilt insbesondere im Rahmen sog. Aerosol-generierender Verfahren wie der Bronchoskopie. Seit der Veröffentlichung konsentierter Empfehlungen zur Durchführung einer Bronchoskopie unter diesen Bedingungen vor mehr als einem halben Jahr hat sich die Gefahrenlage nicht wesentlich verändert, aber aufgrund des erheblichen Erkenntnisgewinns in der Zwischenzeit war ein Update der Empfehlungen notwendig. Die erneuerten Empfehlungen umfassen u. a. die Verminderung der Aerosolentstehung, den persönlichen Schutz der beteiligten Personen sowie Maßnahmen zur besseren Organisation der Abläufe in der Endoskopie, um eine sichere Durchführung auch in Zeiten von COVID-19 zu gewährleisten.
Electrocatalytic Synthesis of gem-Bisarylthio Enamines and α-Phenylthio Ketones via a Radical Process under Mild Conditions
Authors: Meng Xiu-Jin , Mo Zu-Yu , Pan Yong-Zhou , Cheng Shi-Yan , Li Qian-Yu , Tang Hai-Tao , Pan Ying-Ming 
Published: December 2020

AbstractThe novel method for the synthesis of gem-bisarylthio enamines and α-phenylthio ketones was developed via the coupling of α-substituted vinyl azides with thiols in the presence of tetrabutylammonium iodide (TBAI) as a redox catalyst and electrolyte at room temperature. Electronic properties were crucial in the generated products. This protocol features metal- and oxidant-free materials, broad tolerance of substrates, and mild reaction conditions.
Detection and Characterization of Musculoskeletal Cancer Using Whole-Body Magnetic Resonance Imaging
Authors: Isaac Amanda , Lecouvet Frederic , Dalili Danoob , Fayad Laura , Pasoglou Vasiliki , Papakonstantinou Olympia , Ahlawat Shivani , Messiou Christina , Weber Marc-André , Padhani Anwar R. 
Published: December 2020

AbstractWhole-body magnetic resonance imaging (WB-MRI) is gradually being integrated into clinical pathways for the detection, characterization, and staging of malignant tumors including those arising in the musculoskeletal (MSK) system. Although further developments and research are needed, it is now recognized that WB-MRI enables reliable, sensitive, and specific detection and quantification of disease burden, with clinical applications for a variety of disease types and a particular application for skeletal involvement. Advances in imaging techniques now allow the reliable incorporation of WB-MRI into clinical pathways, and guidelines recommending its use are emerging. This review assesses the benefits, clinical applications, limitations, and future capabilities of WB-MRI in the context of other next-generation imaging modalities, as a qualitative and quantitative tool for the detection and characterization of skeletal and soft tissue MSK malignancies.
Interventional Techniques for Bone and Musculoskeletal Soft Tissue Tumors: Current Practices and Future Directions – Part II. Stabilization
Authors: Dalili Danoob , Isaac Amanda , Cazzato Roberto Luigi , Åström Gunnar , Bergh Jonas , Mansour Ramy , Weber Marc-André , Garnon Julien , Gangi Afshin 
Published: December 2020

AbstractPercutaneous image-guided oncologic interventions have rapidly evolved over the last two decades as an independent strategy or used within a first-, second-, or even third-line strategy in the treatment of musculoskeletal (MSK) tumors. Abundant mostly nonrandomized publications have described the safety, efficacy, and reproducibility of implementing percutaneous therapies both with curative and palliative intent. In this article, we continue to share our experience in bone and MSK soft tissue interventions focusing on stabilization and combined ablation and stabilization. We propose a pathway and explore future directions of image-guided interventional oncology related to skeletal disease. We reflect on the advantages and limitations of each technique and offer guidance and pearls to improve outcomes. Representing patterns from our practices, we demonstrate the role of collaborative working within a multidisciplinary team, ideally within a dedicated tumor treatment center, to deliver patient-specific therapy plans that are value based and favored by patients when given the choice.
Therapy in Advanced Hepatocellular Carcinoma
Authors: Javan Hanna , Dayyani Farshid , Abi-Jaoudeh Nadine 
Published: December 2020

AbstractTreatment of advanced hepatocellular carcinoma (HCC) is challenging. Several randomized clinical trials are investigating the efficacy of systemic therapy, immunotherapy, and locoregional therapy as monotherapy or combined with other modalities in the treatment of HCC. Systemic therapy is the preferred treatment in advanced disease. To date, multiple first-line and second-line agents received Food and Drug Administration approval. For over a decade, sorafenib was the only first-line agent. In May 2020, combination of atezolizumab and bevacizumab has been approved as a first-line systemic regimen. Lenvatinib is another first-line agent that has multikinase activity. Second-line agents include cabozantinib, regorafenib, ramucirumab, and nivolumab. Adoptive cell transfer therapy is a highly specific immunotherapy that has shown antitumor activity against HCC. Oncolytic viruses are genetically modified viruses that infect cancer cells and induce apoptosis. Locoregional therapies such as transarterial chemoembolization and radioembolization have shown a potential benefit in selected patients with advanced HCC. In this review, we aim to summarize the treatment options available for advanced HCC.
Intrahepatic Cholangiocarcinoma
Authors: Entezari Pouya , Riaz Ahsun 
Published: December 2020

AbstractCholangiocarcinoma is the second most common primary malignancy of the liver. This review will focus on the mass-forming intrahepatic type of this disease and discuss the role of medical, surgical, and radiation oncology in managing this difficult disease. A global understanding to the management of intrahepatic cholangiocarcinoma (ICC) can help the interventional radiologist understand the role of locoregional therapies such as ablation, transarterial chemoembolization, and radioembolization in the management of ICC.
Locoregional Therapies for the Treatment of Uveal Melanoma Hepatic Metastases
Authors: Gonsalves Carin F. , Adamo Robert D. , Eschelman David J. 
Published: December 2020

AbstractUveal melanoma is the most common primary intraocular malignant tumor in adults. Approximately 50% of patients develop metastatic disease of which greater than 90% of patients develop hepatic metastases. Following the development of liver tumors, overall survival is dismal with hepatic failure being the cause of death in nearly all cases. To prolong survival for patients with metastatic uveal melanoma, controlling the growth of hepatic tumors is essential. This article will discuss imaging surveillance following the diagnosis of primary uveal melanoma; locoregional therapies used to control the growth of hepatic metastases including chemoembolization, immunoembolization, radioembolization, percutaneous hepatic perfusion, and thermal ablation; as well as currently available systemic treatment options for metastatic uveal melanoma.
Tumor-like Lesions of Bone and Soft Tissues and Imaging Tips for Differential Diagnosis
Authors: Örgüç Sebnem , Arkun Remide 
Published: December 2020

AbstractIn the musculoskeletal system, tumor-like lesions may present similar imaging findings as bone and soft tissue tumors and can be defined as tumors on radiologic examinations. Misinterpretation of the imaging findings can lead to inappropriate clinical management of the patient.There is still some debate regarding the pathophysiology and origin of tumor-like lesions that include congenital, developmental, inflammatory, infectious, metabolic, reactive, posttraumatic, post-therapeutic changes, and some miscellaneous entities causing structural changes. Although tumor-like lesions are historically defined as non-neoplastic lesions, some of them are classified as real neoplasms.We discuss a spectrum of entities mimicking tumors of bone and soft tissues that include various non-neoplastic diseases and anatomical variants based on imaging findings.
An In vitro Study to Evaluate and Compare the Dimensional Accuracy of Poly (Methyl Methacrylate) by Injection Molding and Conventional Molding Technique
Authors: Gupta Ambika Shrivastava , Awinashe Vaibhav , Palekar Umesh , Gupta Siddharth , Jain Shilpa , Jain Arpit 
Published: December 2020

Abstract
Introduction Poly(methyl methacrylate) is widely used as denture base material due its better physical properties, ease to fabricate, and repair. Despite being the material of choice for the denture fabrication, dentures made from poly(methyl methacrylate) may exhibit dimensional changes due to volumetric shrinkage. This further affects the retention of the denture. Various methods have been used to overcome this problem. One such method is the use of injection molding technique. So, a study was planned to evaluate the efficacy of dentures processed by injection molding technique in reducing the volumetric shrinkage.
Objective To evaluate and compare the dimensional accuracy of poly(methyl methacrylate) resin processed by conventional and injection molding technique.
Materials and Methods A total of 90 samples were made. Half of the samples (45) were fabricated by compression molding and half (45) by injection molding technique. Dimensional change was studied at three equidistant points in posterior region with the help of digitized travelling microscope. Statistical analysis was done using student’s t-test.
Result Dimensional accuracy of injection molded poly(methyl methacrylate) resin was greater than that of compression molded poly(methyl methacrylate).
The role of biotic interactions in invasion ecology: theories and hypotheses.
Authors: Hui Cang , Landi Pietro , Latombe Guillaume 
Published: December 2020

Abstract

Changes in biotic interactions in the native and invaded range can enable a non-native species to establish and spread in novel environments. Invasive non-native species can in turn generate impacts in recipient systems partly through the changes they impose on biotic interactions; these interactions can lead to altered ecosystem processes in the recipient systems. This chapter reviews models, theories and hypotheses on how invasion performance and impact of introduced species in recipient ecosystems can be conjectured according to biotic interactions between native and non-native species. It starts by exploring the nature of biotic interactions as ensembles of ecological and evolutionary games between individuals of both the same and different groups. This allows us to categorize biotic interactions as direct and indirect (i.e. those involving more than two species) that emerge from both coevolution and ecological fitting during community assembly and invasion. We then introduce conceptual models that can reveal the ecological and evolutionary dynamics between interacting non-native and resident species in ecological networks and communities. Moving from such theoretical grounding, we review 20 hypotheses that have been proposed in invasion ecology to explain the invasion performance of a single non-native species, and seven hypotheses relating to the creation and function of assemblages of non-native species within recipient ecosystems. We argue that, although biotic interactions are ubiquitous and quintessential to the assessment of invasion performance, they are nonetheless difficult to detect and measure due to strength dependency on sampling scales and population densities, as well as the non-equilibrium transient dynamics of ecological communities and networks. We therefore call for coordinated efforts in invasion science and beyond, to devise and review approaches that can rapidly map out the entire web of dynamic interactions in a recipient ecosystem.
Seed dispersal interactions promoting plant invasions.
Authors: Díaz Vélez M. Celeste , Ferreras Ana E. , Paiaro Valeria 
Published: December 2020

Abstract

Animal dispersers are essential for many non-native plants since they facilitate seed movement and might promote seed germination and seedling establishment, thereby increasing their chances of invasion. This chapter reviews the published literature on seed dispersal of non-native plant species by native and/or non-native animals. The following questions are addressed: (i) Are interactions between non-native plants and their animal dispersers evenly studied worldwide? (ii) Which are the distinctive traits (i.e. geographical origin, life form, dispersal strategy and propagule traits) of non-native plants that are dispersed by animals? (iii) Which are the most studied groups of dispersers of non-native plants around the world? (iv) Does the literature provide evidence for the Invasional Meltdown Hypothesis (non-native plant-non-native disperser facilitation)? (v) What is the role of animal dispersers at different stages of the non-native plant regeneration process? Our dataset of 204 articles indicates that geographical distribution of the studies was highly heterogeneous among continents, with the highest number coming from North America and the lowest from Asia and Central America. Most of the non-native plants involved in dispersal studies were woody species from Asia with fleshy fruits dispersed by endozoochory. More than the half of the animal dispersal agents noted were birds, followed by mammals, ants and reptiles. The dominance of bird-dispersal interactions over other animal groups was consistent across geographical regions. Although most of the studies involved only native dispersers, interactions among non-native species were detected, providing support for the existence of invasional meltdown processes. Of the total number of reviewed articles reporting seed removal, 74% evaluated seed dispersal, but only a few studies included seed germination (35.3%), seedling establishment (5.4%) or seed predation (23.5%). Finally, we discuss some research biases and directions for future studies in the area.
EICA 2.0: a general model of enemy release and defence in plant and animal invasions.
Authors: Honor Richard , Colautti Robert I. 
Published: December 2020

Abstract

Plants and animals have evolved a variety of strategies to limit the negative fitness consequences of natural enemies (i.e. herbivores, predators, parasites and pathogens). Demographic bottlenecks occurring during the invasion process reduce the number of co-introduced natural enemies, providing opportunities to study rapid evolution in environments with different or reduced enemy loads. Enemy release theory provides a set of hypotheses and predictions about the role of natural enemies in the proliferation of invasive species. This body of theory includes the Enemy Release Hypothesis (ERH) and the related Evolution of Increased Competitive Ability Hypothesis (EICA), but there is often confusion about these hypotheses and the data needed to test them. We introduce a simple, general model of enemy release to identify and clarify some of the key assumptions and predictions implicit in enemy release theory and its impacts on invasion. Although introduced populations likely benefit from a reduction in the direct fitness impacts of natural enemies in the early stages of invasion, an evolutionary shift in resource allocation from defence to growth and reproduction is much less likely and depends on a delicate balance between the fitness costs and benefits of defence and the fitness impacts of natural enemies in both the native and introduced ranges. Even when the abundance of natural enemies is lower in the introduced range, the majority of scenarios do not favour evolution of less defended genotypes that are more competitive or more fecund, contrary to predictions of EICA. Perhaps surprisingly, we find that the level of damage by natural enemies in field surveys is not generally a good parameter for testing enemy release theory. Instead, common garden experiments characterizing fitness reaction norms of multiple genotypes from the native and introduced range are crucial to estimate the historic rate of adaptive evolution or predict it into the future. Incorporating spatial autocorrelation and methods from population genetics can further improve our understanding of the role of enemy release and evolution in the proliferation of invasive species.
The role of pathogens in plant invasions.
Authors: Kendig Amy E. , Flory S. Luke , Goss Erica M. , Holt Robert D. , Clay Keith , Harmon Philip F. , Lane Brett R. , Adhikari Ashish , Wojan Christopher M. 
Published: December 2020

Abstract

Plant-pathogen interactions occur throughout the process of plant invasion: pathogens can acutely influence plant survival and reproduction, while the large densities and spatial distributions of invasive plant species can influence pathogen communities. However, interactions between invasive plants and pathogens are often overlooked during the early stages of invasion. As with introductions of invasive plants, the introduction of agricultural crops to new areas can also generate novel host-pathogen interactions. The close monitoring of agricultural plants and resulting insights can inform hypotheses for invasive plants where research on pathogen interactions is lacking. This chapter reviews the known and hypothesized effects of pathogens on the invasion process and the effects of plant invasion on pathogens and infectious disease dynamics throughout the process of invasion. Initially, pathogens may inhibit the transport of potentially invasive plants. After arrival in a new range, pathogens can facilitate or inhibit establishment success of introduced plants depending on their relative impacts on the introduced plants and resident species. As invasive plants spread, they may encounter novel pathogens and alter the abundance and geographic range of pathogens. Pathogens can mediate interactions between invasive plants and resident species and may influence the long-term impacts of invasive plants on ecosystems. As invasive plants shift the composition of pathogen communities, resident species could be subject to higher disease risk. We highlight gaps in invasion biology research by providing examples from the agricultural literature and propose topics that have received little attention from either field.
Direct and indirect effects of herbivores influencing plant invasions.
Authors: Kotanen Peter M. 
Published: December 2020

Abstract

Non-native plants rarely escape damage by herbivores. Instead, upon arrival in a new region, they begin to acquire new enemies, replacing those they have lost during their migration. These herbivores can include both natives to the new region and species that have themselves been accidentally or deliberately introduced from elsewhere, potentially including examples originating from the invader's original range. Shifts of new enemies from other hosts can occur over a range of timescales, depending in part on whether evolutionary change is required, but are likely to be faster for plants that are widespread and phylogenetically related to a herbivore's original host, and faster for generalist herbivores than for specialists. The occurrence of herbivores is not necessarily uniform across an invader's range; instead, they may be less diverse or abundant in host populations that are geographically or ecologically marginal, though existing evidence is mixed. Collectively, these new suites of herbivores can affect the growth and fitness of invaders, both directly by damaging them and indirectly by attacking their competitors. Studies comparing the demographic consequences of herbivory for successful vs unsuccessful invaders may help to clarify how often such impacts limit invasiveness. The view that an invader enters 'enemy-free' space is inaccurate; instead, persistence and spread of non-native plants often may be affected by the novel and changing assemblage of herbivores that they acquire within their new distribution.
Competition between native and non-native plants.
Authors: Wandrag Elizabeth M. , Catford Jane A. 
Published: December 2020

Abstract

The introduction of species to new locations leads to novel competitive interactions between resident native and newly-arriving non-native species. The nature of these competitive interactions can influence the suitability of the environment for the survival, reproduction and spread of non-native plant species, and the impact those species have on native plant communities. Indeed, the large literature on competition among plants reflects its importance in shaping the composition of plant communities, including the invasion success of non-native species. While competition and invasion theory have historically developed in parallel, the increasing recognition of the synergism between the two themes has led to new insights into how non-native plant species invade native plant communities, and the impacts they have on those plant communities. This chapter provides an entry point into the aspects of competition theory that can help explain the success, dominance and impacts of invasive species. It focuses on resource competition, which arises wherever the resources necessary for establishment, survival, reproduction and spread are in limited supply. It highlights key hypotheses developed in invasion biology that relate to ideas of competition, outlines biotic and abiotic factors that influence the strength of competition and species' relative competitive abilities, and describes when and how competition between non-native and native plant species can influence invasion outcomes. Understanding the processes that influence the strength of competition between non-native and native plant species is a necessary step towards understanding the causes and consequences of biological invasions.