bluuebunny/crossref_metadata_2025_split huggingface dataset:
Traffic sign detection and recognition by improving Region of Interest (ROI) division to support driver assistance system
Authors: Suheryadi A , Sumarudin A , Puspaningrum A , Prastyo E 
Published: May 2020

Abstract
Traffic signs detection and recognition is a technology that allows automatic identification of traffic signs. In the implementation, it mostly uses a camera to capture video or real-time conditions. The Traffic detection and recognition system can give benefits to improve safety for drivers or passengers. Therefore, traffic signs detection and recognition system are one of the important parts in Driver Assistance Systems (DAS), besides that it is also used in video surveillance to improve traffic safety in the field of Intelligent Transportation System (ITS). In this paper, we propose a method for detecting and recognizing traffic signs by combining color and shape detection and divide the interest object to several regions for object recognition. The first step is image transformation, which aims to determine interest objects in the camera view. Such a process was using hue, saturation, value (HSV) color space, grey level, and black and white (BW) level. The next step is the filter and the segmentation process. The result of the filter and segmentation process then detects area objects by using region determination. The last step is the region of interest (ROI), which is used to recognizing sign traffic by the sum of absolute differences (SAD), and we try to improve area selection of ROI around nine parts. The results of the experiment proved that the proposed method was relatively good with the success rate for detecting objects about 97,38 %, and the true positive of recognition result about 81,67 %.
Performance analysis of Pico Hydro-Solar Photovoltaic Hybrid System
Authors: Ratnata I W , Sumarto S , Saputra W S 
Published: May 2020

Abstract
This paper presents experimental results from the operation of the prototype of Pico Hydro-Solar Photovoltaic Hybrid System. This device includes a pico hydro power with a capacity of 600 VA, a 3x200 WP solar panel, 4x60Ah energy storage, solar charge controller, a 1500 W inverter, and a 15-200 watt variable load. In this experiment, measurements of the current flow and terminal voltage were carried out at the output of photovoltaic, picohydro, battery, and inverter at various different load values, ranging from 15 watts to 200 watts. Measurements are made during the day when the intensity of solar radiation is quite high. The measurement results show that the output voltage on each component is relatively stable at various load values, and the load energy requirements are supplied more by solar photovoltaic components in sunny weather and more by pico-hydro in cloudy weather.
Oyster mushroom cultivation solution based IoT for Nova Farmers
Authors: Fauzi R M , Waranti F S , Rais I K , Somantri Y 
Published: May 2020

Abstract
Nova Farmers is a group of oyster mushroom farmers in Pasirhalang Village, Cikarangmulya, West Bandung, which has a vertical mushroom baglog. Farmers who are dominated by women need to climb Baglog to water Baglog at every level. The purpose of this study is to design a tool that can maximize the growth of oyster mushrooms, temperature, and humidity of the kumbung to be maintained at temperatures of 28 ° C and 80% through watering. To improve watering techniques by farmers, oyster mushroom sprinklers are automatically made based on the Internet of Things that takes into account temperature and humidity factors that can be monitored and controlled through the ABUJAT android application using Android Studio software. The sprinkler section can move vertically up and down to be able to sprinkle all baglogs at each level. This system is made using a DC PG45 motor to drive the sprinkler section which is controlled by DOIT ESP32 DevKit V1 as a microcontroller and combined with a DHT22 sensor as a temperature and humidity sensor, DS1307 RTC module, water sensor, buzzer module for watering the alarm notification, 12VDC pump for pumping water, 16x2 LCD to display sensor values, limit switches, and BTS7960 motor drivers. Based on the results of the experiment, our application can function properly and can be used by Nova Farmers.
Synthesis of ZnO/C dots as antibacterial dental bracket
Authors: Taufiq H R , Mirza M , Paramita S A , Sutanto H 
Published: May 2020

Abstract
Demineralization brackets has caused serious problems in orthodontic techniques effect by increasing streptococcus mutans bacteria in the mouth. To overcome this problem, antibacterial brackets based on ZnO and carbon dots materials were made using spray coating-microwave irradiation methods which have environmentally friendly, non-toxic and low-cost. C-dots with variations power of microwave are 450 W and 540 W were successfully made with microwave time of 15, 30 and 45 minutes. Optical properties showed the highest absorbance owned by ZnO/C-dots at 15 minutes and power of 450 W. Data obtained in the form of absorbance graphs were then processed using the Tauch Plot method to determine the value of the energy band gap. The shift of light absorption of ZnO/C-dots towards the higher wavelength causes a decrease in the energy band gap of 3.16 eV from before ZnO value is 3.26 eV. Therefore, ZnO/C-dots is effectively used under visible light radiation. After modification with C-dots, the surface of the bracket shows a more rugged morphology, covered by a dense and uniform ZnO/C-dots layer which is useful for protecting brackets.
Photocatalytic degradation of heavy metal in dairy milk by N-doped ZnO thin film using spray coating technique
Authors: Pratiwi N I , Ilsatoham M I , Asror M Z , Sutanto H 
Published: May 2020

Abstract
Zinc Oxide (ZnO) is a photocatalytic material. N-doped ZnO thin film can reduce heavy metals in milk. In the process, N-doped ZnO thin film photocatalyst is deposited on the glass by spray coating technique. N-doped ZnO thin film was characterized using UV-Vis (Ultraviolet/Visible Spectroscopy), X-Ray Diffraction (XRD) and FTIR (Fourier Transform Infrared). This study aims to investigate the reduction of heavy metals in milk due to N-doped ZnO thin film. In this study, dairy milk was obtained from farms in Central Java. Characterization results show that the band gap of N-doped ZnO thin film is 3.2 eV that N- doped ZnO thin film can function under visible light. Photocatalytic activity of prepared N-doped ZnO thin film was evaluated by the degradation of heavy metals in dairy milk. Duration of N-doped ZnO thin film degradation was found to vary from 0, 60, and 120 to 180 minutes. Heavy metal content in dairy milk is 0.5775 ppm. Addition of N-doped ZnO thin film to dairy milk reduced heavy metal content to 0.0053 ppm. In can then be inferred that heavy metal degradation using N-doped ZnO thin film is by as much as 89-99 %.
The sensitivity of sensor based on Microring Resonator (MRR) and Surface Plasmon Resonance (SPR) for diabetes monitoring application
Authors: Nugroho H S , Hasanah L , Wulandari C , Pawinanto R E , Haron M H , Menon P S , Zain A R M , Berhanuddin D D , Mulyanti B 
Published: May 2020

Abstract
Diabetes mellitus is a disease of metabolic disorders where human blood contains a high amount of sugar level for a prolonged period. This study aims to simulate how effective sensor based on MRR and SPR for the purpose of diabetes monitoring. The results show that sensor based on MRR and SPR provides the ability to detect low level of glucose concentration as low as 7 mmol/L (0.13%) and the ability to detect resonance shift for very small glucose concentration change. Therefore, the sensor based on MRR and SPR can be used for diabetes monitoring. The sensitivity of the sensor based on MRR and SPR is 85.84 nm/RIU and 116.69 °/RIU respectively. These findings are important for the development of diabetes monitoring based on MRR or SPR.
Analysis characteristic of cholesteryl acrylate conductivity with the addition of the PE-b-PEG doped ITO-nanoparticle in the development of liquid crystal technology
Authors: Ismail M , Afrizal A , Syafei D I , Puspita M A 
Published: May 2020

Abstract
The study of liquid crystal material is very interesting and has the opportunity as a smart material such as cholesteryl acrylate. Liquid crystal cholesteryl acrylate can be made shynthesized by Acryloiloxy Butyloxy Benzoate (ABB) precursor and cholesterol. Cholesteryl acrylate was polymerized by the ultraviolet curing (UV-Curing) method to keep the crystal structure stable. During the polymerization process some ingredients are added which can increase and regulate the formation of liquid crystal structure phases. Cholesteryl acrylate can be doped by adding conductive oxide in the form of nano particle scale Indium Tin Oxide (18 nm). The optimum conductivity results were 5.70 × 10−7 S/m with the addition of ITO 10% w/w. The structure of the crystal phase formed can be directed by the addition of Polyethylene-block-Polyethylene Glycol during the UV-Curing process. The hydrophobic part of PE block will interact with hydrophobic liquid crystal molecules, while the hydrophilic part of the PEG block has a high affinity for the hydrophilic ITO electrode substrate. The added PE-b-PEG varies from 0.001 to 0.005 percent by weight of polymer cholesteryl acrylate composite. Conductance data is measured using LCR meters from a frequency of 50 Hertz to 5000 kHertz. The average conductance data for ITO is 0.09597838 S, cholesteryl acrylate is 5.20635 × 10−6 S, the polymer cholesteryl acrylate composite with doped ITO is 4.58284 × 10−6 S. When added PE-b-PEG 0,003 percent composite weight is obtained the highest average conductance data is 1.24234 × 10−5 S with an average conductivity value of 6.09 × 10−5 S/m. The varies composition of PE-b-PEG content is very influential to regulate the arrangement of crystals formed in electrical conductivity.
Design of a compact UWB Wilkinson Power Divider using ring structured and tapered line matching transformer
Authors: Yuniar R N , Hariyadi T , Saripudin A , Mulyanti B 
Published: May 2020

Abstract
There is an increasing interest in the design of ultra-wideband (UWB) microwave components for UWB applications. One of the important components in the ultra-wideband application is power divider. In this paper, an ultra-wideband Wilkinson power divider (WPD) using ring structure and tapered line matching transformer is proposed. The aims of this research are to design an UWB WPD for feeding antenna UWB in use of detecting breast cancer. The method used in this research is simulation using finite integration based on CST STUDIO SUITE 2015 3D EM simulator software. This study shows the improvement of output responses due to the introduction of a tapered line and added isolation resistors. The bandwidth and input reflection coefficient are also improved by the ring structure. The proposed UWB WPD can be used for 1:2-way equal power division application in ultra-wideband range, such as UWB antenna which is operating in frequency 3-13 GHz. The simulation result shows that the return loss is better than -10 dB and the insertion loss is about 3.2 dB until 4.15 dB for the operating frequencies and impedance value of 50 ohms.
Design of array microstrip antenna with circular polarization for Broadband Tracking System Application
Authors: Alam S , Surjati I , Sari L , Ningsih Y K , Wibowo T 
Published: May 2020

Abstract
This paper proposes the design and simulation of microstrip array antennas with 4x1 elements that have circular polarization for Broadband Antenna Tracking System (BATS) applications. The proposed antenna is designed to work at a frequency of 11 GHz by using FR-4 type substrate with a dielectric constant 4.3, thickness (h) 1.6 mm and loss tangent (tan α) 0.0265. Circular polarization with axial ratio ≤ 3 dB was obtained using the truncated corner technique while the 4x1 element array technique was used to increase the bandwidth of the proposed antenna. From the simulation results obtained return loss of -29.71 dB and VSWR 1.068 at the working frequency of 11 GHz. The bandwidth of the proposed antenna is 1663 MHz in the frequency range 10582 GHz - 12215 MHz. The axial ratio of the proposed antenna is ≤ 3 dB, which is 2.462 dB at the working frequency of 11 GHz. Based on the results obtained from the design and simulation process, the proposed antenna has worked in accordance with the specified working frequency and is suitable for the Broadband Tracking System application.
Design and realization of 4 way Chebyshev Wilkinson power divider at 3 GHz frequency for 3 dimensional radar application
Authors: Khoirini D R , Hariyadi T , Pantjawati A B 
Published: May 2020

Abstract
In the radar system, detection of objects with high accuracy is needed. Therefore, a low sidelobe antenna is needed to avoid interference from other detected targets. One method to suppress sidelobe antenna is by using unequal power divider with Chebyshev polynomial excitation coefficients. In this paper, we will discuss about the design and fabrication of Chebyshev Wilkinson power divider for 3 dimensional radar application. This research was conducted through 4 stages, namely design, simulation, fabrication and measurement. This power divider is realized in the form of a microstrip using Rogers R0-4003C (lossy) substrate with a thickness of 1,524 mm and a dielectric constant of 3.55. The simulation and measurement results are met the desired specifications, the operating frequency is at 3 GHz with a bandwidth of 200 MHz, the return loss is less than -10 dB, the insertion loss value is in accordance with Chebyshev, the isolation value of the port is less than -10 dB, and the unbalance phase is smaller than 2.5°.
Analysis of the relevance between Vocational High School competencies and the needs of the industrial sector on Computer and Network Engineering Competencies
Authors: Kamilah S , Budi A H S , Purnama W 
Published: May 2020

Abstract
The curriculum applied in vocational schools aims to synchronize graduate competencies with the demands of the industrial sector on workforce competencies. This study aims to analyze the relevance of the 2013 Vocational High School curriculum on Computer and Network Engineering Competencies and the needs of the workforce in the Telecommunications Industry Sector. This research was conducted using quantitative descriptive methods. The study population was the Vocational High School and the Telecommunications Industry in West Java Province and DKI Jakarta. The sample is determined by purposive sampling technique for the Telecommunications Industry and saturated sampling for Vocational High Schools. Participants in this study were 6 respondents from the Vocational High School and 21 respondents from the Telecommunications Industry. The research instrument used was a questionnaire. The analysis technique used is recall and precision. The results showed a high relevance between Basic Competence in the field of computer and network engineering and the need for workforce in the telecommunications industry sector by 83.84%.
Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients That Should Be Ramped Up Immediately as Key to the Pandemic Crisis
Authors: Risch Harvey A 
Published: May 2020

Abstract
More than 1.6 million Americans have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and more than 10 times that number carry antibodies to it. High-risk patients with progressing symptomatic disease currently have only hospitalization treatment, with its high mortality, available to them. An outpatient treatment that prevents hospitalization is desperately needed. Two candidate medications have been widely discussed: remdesivir and hydroxychloroquine (HCQ) + azithromycin (AZ). Remdesivir has shown mild effectiveness in hospitalized inpatients, but no trials in outpatients have been registered. HCQ + AZ has been widely misrepresented in both clinical reports and public media, and results of outpatient trials are not expected until September. Early outpatient illness is very different from later florid disease requiring hospitalization, and the treatments differ. Evidence about use of HCQ alone, or of HCQ + AZ in inpatients, is irrelevant with regard to the efficacy of HCQ + AZ in early high-risk outpatient disease. Five studies, including 2 controlled clinical trials, have demonstrated significant major outpatient treatment efficacy. HCQ + AZ has been used as the standard of care in more than 300,000 older adults with multiple comorbid conditions; the estimated proportion of such patients diagnosed with cardiac arrhythmia attributable to the medications is 47 per 100,000 users, among whom estimated mortality is less than 20% (9/100,000 users), as compared with the 10,000 Americans now dying each week. These medications need to be made widely available and promoted immediately for physicians to prescribe.
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data
Authors: Dong Kangning , Zhang Shihua 
Published: May 2020

Abstract
The rapid accumulation of single-cell chromatin accessibility data offers a unique opportunity to investigate common and specific regulatory mechanisms across different cell types. However, existing methods for cis-regulatory network reconstruction using single-cell chromatin accessibility data were only designed for cells belonging to one cell type, and resulting networks may be incomparable directly due to diverse cell numbers of different cell types. Here, we adopt a computational method to jointly reconstruct cis-regulatory interaction maps (JRIM) of multiple cell populations based on patterns of co-accessibility in single-cell data. We applied JRIM to explore common and specific regulatory interactions across multiple tissues from single-cell ATAC-seq dataset containing ~80 000 cells across 13 mouse tissues. Reconstructed common interactions among 13 tissues indeed relate to basic biological functions, and individual cis-regulatory networks show strong tissue specificity and functional relevance. More importantly, tissue-specific regulatory interactions are mediated by coordination of histone modifications and tissue-related TFs, and many of them may reveal novel regulatory mechanisms.
Accurate prediction of genome-wide RNA secondary structure profile based on extreme gradient boosting
Authors: Ke Yaobin , Rao Jiahua , Zhao Huiying , Lu Yutong , Xiao Nong , Yang Yuedong 
Published: May 2020

Abstract

Motivation
RNA secondary structure plays a vital role in fundamental cellular processes, and identification of RNA secondary structure is a key step to understand RNA functions. Recently, a few experimental methods were developed to profile genome-wide RNA secondary structure, i.e. the pairing probability of each nucleotide, through high-throughput sequencing techniques. However, these high-throughput methods have low precision and cannot cover all nucleotides due to limited sequencing coverage.

Results
Here, we have developed a new method for the prediction of genome-wide RNA secondary structure profile from RNA sequence based on the extreme gradient boosting technique. The method achieves predictions with areas under the receiver operating characteristic curve (AUC) &gt;0.9 on three different datasets, and AUC of 0.888 by another independent test on the recently released Zika virus data. These AUCs are consistently &gt;5% greater than those by the CROSS method recently developed based on a shallow neural network. Further analysis on the 1000 Genome Project data showed that our predicted unpaired probabilities are highly correlated (&gt;0.8) with the minor allele frequencies at synonymous, non-synonymous mutations, and mutations in untranslated regions, which were higher than those generated by RNAplfold. Moreover, the prediction over all human mRNA indicated a consistent result with previous observation that there is a periodic distribution of unpaired probability on codons. The accurate predictions by our method indicate that such model trained on genome-wide experimental data might be an alternative for analytical methods.

Availability and implementation
The GRASP is available for academic use at https://github.com/sysu-yanglab/GRASP.

Supplementary information
Supplementary data are available online.
AOP4EUpest: mapping of pesticides in adverse outcome pathways using a text mining tool
Authors: Jornod Florence , Rugard Marylène , Tamisier Luc , Coumoul Xavier , Andersen Helle R , Barouki Robert , Audouze Karine 
Published: May 2020

Abstract

Motivation
Exposure to pesticides may lead to adverse health effects in human populations, in particular vulnerable groups. The main long-term health concerns are neurodevelopmental disorders, carcinogenicity as well as endocrine disruption possibly leading to reproductive and metabolic disorders. Adverse outcome pathways (AOP) consist in linear representations of mechanistic perturbations at different levels of the biological organization. Although AOPs are chemical-agnostic, they can provide a better understanding of the Mode of Action of pesticides and can support a rational identification of effect markers.

Results
With the increasing amount of scientific literature and the development of biological databases, investigation of putative links between pesticides, from various chemical groups and AOPs using the biological events present in the AOP-Wiki database is now feasible. To identify co-occurrence between a specific pesticide and a biological event in scientific abstracts from the PubMed database, we used an updated version of the artificial intelligence-based AOP-helpFinder tool. This allowed us to decipher multiple links between the studied substances and molecular initiating events, key events and adverse outcomes. These results were collected, structured and presented in a web application named AOP4EUpest that can support regulatory assessment of the prioritized pesticides and trigger new epidemiological and experimental studies.

Availability and implementation
http://www.biomedicale.parisdescartes.fr/aop4EUpest/home.php.

Supplementary information
Supplementary data are available at Bioinformatics online.
Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†
Authors: Devlin Darius J , Nozawa Kaori , Ikawa Masahito , Matzuk Martin M 
Published: May 2020

AbstractFamilies with sequence similarity 170 members A and B (FAM170A and FAM170B) are testis-specific, paralogous proteins that share 31% amino acid identity and are conserved throughout mammals. While previous in vitro experiments suggested that FAM170B, an acrosome-localized protein, plays a role in the mouse sperm acrosome reaction and fertilization, the role of FAM170A in the testis has not been explored. In this study, we used CRISPR/Cas9 to generate null alleles for each gene, and homozygous null (−/−) male mice were mated to wild-type females for 6 months to assess fertility. Fam170b−/− males were found to produce normal litter sizes and had normal sperm counts, motility, and sperm morphology. In contrast, mating experiments revealed significantly reduced litter sizes and a reduced pregnancy rate from Fam170a−/− males compared with controls. Fam170a−/−;Fam170b−/− double knockout males also produced markedly reduced litter sizes, although not significantly different from Fam170a−/− alone, suggesting that Fam170b does not compensate for the absence of Fam170a. Fam170a−/− males exhibited abnormal spermiation, abnormal head morphology, and reduced progressive sperm motility. Thus, FAM170A has an important role in male fertility, as the loss of the protein leads to subfertility, while FAM170B is expendable. The molecular functions of FAM170A in spermatogenesis are as yet unknown; however, the protein localizes to the nucleus of elongating spermatids and may mediate its effects on spermatid head shaping and spermiation by regulating the expression of other genes. This work provides the first described role of FAM170A in reproduction and has implications for improving human male infertility diagnoses.