bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survey of current practices and opinions of German Society of Gynecologic Endoscopy members regarding the treatment of ovarian neoplasia by robotic surgery
Authors: Zimmermann J. S. M. , Radosa J. C. , Radosa M. P. , Sklavounos P. , Schweitzer P. A. , Solomayer E. F. 
Published: November 2020

Abstract
Purpose
As data on this topic are sparse and contradictory, we aimed to ascertain the opinions of the members of the German Society of Gynecologic Endoscopy (AGE) regarding the use of robotic surgery in the treatment of ovarian malignancies.

Methods
In 2015, an anonymous questionnaire was sent to AGE members to assess their views on the treatment of ovarian malignancies by robotic surgery according to T stage and the current treatment practices in their facilities.

Results
Of the 228 respondents, 132 (58%) were fellows or attending physicians and 156 (68%) worked at university hospitals or tertiary referral centers. Most [n = 218 (96%)] respondents reported treating < 10% of their patients using robotic surgery. Respondents felt that T1 and borderline ovarian tumors, but not T2 (51%) or T3/4 (76%) tumors, should and could be treated by robot surgery. 162 (71%) respondents considered the currently available data on this subject to be insufficient, and 42% indicated their willingness to participate in clinical studies on the applicability of robotic surgery to the treatment of T1/2 ovarian tumors.

Conclusion
The majority of AGE members surveyed considered robotic surgery to be an option for the treatment of T1 ovarian malignancies and borderline ovarian tumors. However, prospective randomized studies are needed to determine the relevance of robotic surgery in this context.
SOM-based aggregation for graph convolutional neural networks
Authors: Pasa Luca , Navarin Nicolò , Sperduti Alessandro 
Published: November 2020

AbstractGraph property prediction is becoming more and more popular due to the increasing availability of scientific and social data naturally represented in a graph form. Because of that, many researchers are focusing on the development of improved graph neural network models. One of the main components of a graph neural network is the aggregation operator, needed to generate a graph-level representation from a set of node-level embeddings. The aggregation operator is critical since it should, in principle, provide a representation of the graph that is isomorphism invariant, i.e. the graph representation should be a function of graph nodes treated as a set. DeepSets (in: Advances in neural information processing systems, pp 3391–3401, 2017) provides a framework to construct a set-aggregation operator with universal approximation properties. In this paper, we propose a DeepSets aggregation operator, based on Self-Organizing Maps (SOM), to transform a set of node-level representations into a single graph-level one. The adoption of SOMs allows to compute node representations that embed the information about their mutual similarity. Experimental results on several real-world datasets show that our proposed approach achieves improved predictive performance compared to the commonly adopted sum aggregation and many state-of-the-art graph neural network architectures in the literature.
Fracture Initiation, Gas Ejection, and Strain Waves Measured on Specimen Surfaces in Model Rock Blasting
Authors: Zhang Zong-Xian , Chi Li Yuan , Qiao Yang , Hou De-Feng 
Published: November 2020

AbstractCrack velocity, gas ejection, and stress waves play an important role in determining delay time, designing a blast and understanding the mechanism of rock fragmentation by blasting. In this paper, the emerging times of the earliest cracks and gas ejection on the lateral surfaces of cylindrical granite specimens with a diameter of 240 mm and a length of 300 mm were determined by high-speed photography, and the strain waves measured by an instrument of dynamic strain measurement during model blasting. The results showed that: (1) the measured velocity of gas penetration into the radial cracks was in a range of 196–279 m/s; (2) the measured velocity of a radial crack extending from the blasthole to the specimen surface varied from 489 to 652 m/s; (3) the length of strain waves measured was about 2800 µs, which is approximately 1000 times greater than the detonation time. At about 2850 µs after detonation was initiated, gases were still ejected from the surface cracks, and the specimens still stood at their initial places, although surface cracks had opened widely.
Responses of Temperate Forests to Nitrogen Deposition: Testing the Explanatory Power of Modeled Deposition Datasets for Vegetation Gradients
Authors: Roth Marina , Michiels Hans-Gerhard , Puhlmann Heike , Sucker Carina , Winter Maria-Barbara , Hauck Markus 
Published: November 2020

AbstractEutrophication due to increased nitrogen concentrations is known to alter species composition and threaten sensitive habitat types. The contribution of atmospheric nitrogen deposition to eutrophication is often difficult to determine. Various deposition models have been developed to estimate the amount of nitrogen deposited for both entire regions and different landscape surface types. The question arises whether the resulting deposition maps allow direct conclusions about the risk of eutrophication-related changes in the understory vegetation composition and diversity in nitrogen-sensitive forest ecosystems. We combined vegetation and soil data recorded across eutrophication gradients in ten oligo-mesotrophic forest types in southwest Germany with datasets from two different deposition models specifically fitted for forests in our study region. Altogether, 153 forest stands, with three sampling replicates each, were examined. Linear mixed-effect models and NMDS analyses revealed that other site factors, in particular the soil C/N ratio, soil pH and canopy cover, played a greater role in explaining vegetation gradients than nitrogen deposition. The latter only rarely had effects on species richness (positive), nitrophyte cover (positive or negative) and the cover of sensitive character species (negative). These effects varied depending on the deposition model used and the forest types examined. No effects of nitrogen deposition on average Ellenberg N values were found. The results reflect the complex situation in forests where nitrogen availability is not only influenced by deposition but also by nitrogen mineralization and retention which depend on soil type, pH and (micro)climate. This context dependency must be regarded when evaluating the effects of nitrogen deposition.
Feasibility and Acceptability of an Adolescent-Friendly Rap Video to Improve Health Literacy Among HIV-Positive Youth in Urban Peru
Authors: Rodriguez Carly A. , Winnett Alexander , Wong Milagros , Krishnam Neha , Martínez Nicole Ocasio , Perez Lady J. , Kolevic Lenka , Lecca Leonid , Franke Molly F. 
Published: November 2020

AbstractClinical outcomes among adolescents living with HIV (ALHIV) might be improved by interventions aimed at addressing limited health literacy. We developed a Spanish-language rap video on HIV concepts and examined its acceptability and feasibility as a learning tool among ALHIV in Lima, Peru. Twenty-eight ALHIV receiving care at an urban pediatric hospital and ten stakeholders engaged in the care of adolescents watched the video. Adolescents completed a pre- and post-video questionnaire. We conducted focus groups with ALHIV and in-depth interviews with stakeholders and analyzed transcripts to identify themes. ALHIV described concepts of CD4 cell count and viral load as they were portrayed. Participants reported the video was relatable, accessible, and provided hope that ALHIV could lead healthy lives and advocated for future videos to address topics such as transmission and sexual health. Questionnaires indicated some improvement in viral load knowledge. An HIV health literacy music video intervention was feasible to implement and accepted by ALHIV and their healthcare providers. Communicating HIV knowledge via music videos may be promising; further study is needed to optimize implementation.
Torsion Pairs and Quasi-abelian Categories
Authors: Tattar Aran 
Published: November 2020

AbstractWe define torsion pairs for quasi-abelian categories and give several characterisations. We show that many of the torsion theoretic concepts translate from abelian categories to quasi-abelian categories. As an application, we generalise the recently defined algebraic Harder-Narasimhan filtrations to quasi-abelian categories.
Assessing microbial residues in soil as a potential carbon sink and moderator of carbon use efficiency
Authors: Geyer Kevin , Schnecker Jörg , Grandy A. Stuart , Richter Andreas , Frey Serita 
Published: November 2020

AbstractA longstanding assumption of glucose tracing experiments is that all glucose is microbially utilized during short incubations of ≤2 days to become microbial biomass or carbon dioxide. Carbon use efficiency (CUE) estimates have consequently ignored the formation of residues (non-living microbial products) although such materials could represent an important sink of glucose that is prone to stabilization as soil organic matter. We examined the dynamics of microbial residue formation from a short tracer experiment with frequent samplings over 72 h, and conducted a meta-analysis of previously published glucose tracing studies to assess the generality of these experimental results. Both our experiment and meta-analysis indicated 30–34% of amended glucose-C (13C or 14C) was in the form of residues within the first 6 h of substrate addition. We expand the conventional efficiency calculation to include residues in both the numerator and denominator of efficiency, thereby deriving a novel metric of the potential persistence of glucose-C in soil as living microbial biomass plus residues (‘carbon stabilization efficiency’). This new metric indicates nearly 40% of amended glucose-C persists in soil 180 days after amendment, the majority as non-biomass residues. Starting microbial biomass and clay content emerge as critical factors that positively promote such long term stabilization of labile C. Rapid residue production supports the conclusion that non-growth maintenance activity can illicit high demands for C in soil, perhaps equaling that directed towards growth, and that residues may have an underestimated role in the cycling and sequestration potential of C in soil.
Phase I study of liposomal irinotecan in patients with metastatic breast cancer: findings from the expansion phase
Authors: Sachdev Jasgit C. , Munster Pamela , Northfelt Donald W. , Han Hyo Sook , Ma Cynthia , Maxwell Fiona , Wang Tiffany , Belanger Bruce , Zhang Bin , Moore Yan , Thiagalingam Arunthathi , Anders Carey 
Published: November 2020

Abstract
Purpose
Metastatic breast cancer (mBC) remains incurable and is associated with low survival rates. This study assessed the efficacy and safety of liposomal irinotecan in heavily pretreated patients with mBC, with or without active brain metastases (BM).

Methods
Following the dose escalation phase and determination of recommended phase 2 dose, the expansion phase of this phase I, open-label, non-randomized study, assigned adult women to cohorts based on mBC subtype: cohort 1, hormone receptor +/human epidermal growth factor receptor 2−; cohort 2, triple-negative breast cancer; or cohort 3, any mBC subtype with active BM. Patients received liposomal irinotecan 50 or 70 mg/m2 free base every 2 weeks. Here, we report secondary outcomes including best overall response (BOR), objective response rate (ORR), and treatment-emergent adverse events (TEAEs).

Results
For non-central nervous system (non-CNS) disease across all cohorts (intent-to-treat population, N = 29), the ORR was 34.5% (95% confidence interval: 17.94–54.33), with a BOR of partial response in 10 patients (34.5%), stable disease in five (17.2%), progressive disease in 10 (34.5%); four patients were unevaluable (13.8%). The ORR for the CNS cohort was 30.0% (95% confidence interval: 6.67–65.25) using modified Response Evaluation Criteria in Solid Tumors. Common grade 3 or higher TEAEs were diarrhea (27.6%), nausea (17.2%), fatigue (13.8%), asthenia (10.3%), and hypokalemia (10.3%). Serious treatment-related TEAEs were reported in six patients (20.7%). No treatment-related TEAEs resulted in death.

Conclusions
Liposomal irinotecan monotherapy demonstrated antitumor activity in heavily pretreated patients with mBC, with or without BM. The observed safety profile was consistent with that in previous studies.
Clinical trial registration: Trial registration ID NCT01770353.
Clinical efficacy of 0.01% atropine in retarding the progression of myopia in children
Authors: Zhao Qi , Hao Qian 
Published: November 2020

Abstract
Purpose
To investigate the clinical efficacy of 0.01% atropine in slowing the progression of myopia in children and to evaluate the influence of 0.01% atropine on secretion of basal tear and stability of tear film.

Methods
Eighty children aged 5–14 years with myopia, 40 were randomly divided into two groups consisting of those who received spectacles in addition to 0.01% atropine (SA group) and those who received only spectacles (S group). The remaining 40 children who were wearing orthokeratology (OK) lenses for 3 months were randomly divided into two groups comprising those who received OK lenses in addition to 0.01% atropine (OKA group) and those who received only OK lenses (OK group). Comprehensive ophthalmologic examinations, including slit-lamp examination, visual acuity testing, autorefraction, intraocular pressure, axial length (AL), corneal topography, Schirmer’s test, and tear film break-up time (TBuT), were performed before treatment and after every 3 months treatment.

Results
During the follow-up visits, evidently better spherical equivalent (SE) control over 3, 6 and 12 months was observed in the SA and OKA groups compared with the S and OK groups. The AL over 3, 6, and 12 months was evidently inhibited in the SA and OKA groups compared with the S and OK groups. No statistically significant differences in Schirmer’s test and TBuT results were observed between the S and SA groups and between the OK and OKA groups. However, statistically significant differences were found in TBuT results between before treatment and after 3 months treatment in the OK group (P < 0.05, paired t test) and the OKA group (P < 0.05, paired t test).

Conclusions
0.01% atropine can effectively control myopia progression and axial elongation regardless of combined treatment with spectacles or OK lenses. And 0.01% atropine has no evident effect on Schirmer’s test and TBuT results; however, researchers also found that Schirmer’s test and TBuT results showed a tendency to reduce after treatment with 0.01% atropine.
Sensitivity to Social Agency in Autistic Adults
Authors: Morgan Emma J. , Foulsham Thomas , Freeth Megan 
Published: November 2020

AbstractThe presence of other people, whether real or implied, can have a profound impact on our behaviour. However, it is argued that autistic individuals show decreased interest in social phenomena, which leads to an absence of these effects. In this study, the agency of a cue was manipulated such that the cue was either described as representing a computer program or the eye movements of another participant. Both neurotypical and autistic participants demonstrated a social facilitation effect and were significantly more accurate on a prediction task when they believed the cue represented another participant. This demonstrates that whilst autistic adults may show difficulties in interpreting social behaviour this does not necessarily arise from a lack of sensitivity to social agency.
A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression
Authors: Mason David , Capp Simone J. , Stewart Gavin R. , Kempton Matthew J. , Glaser Karen , Howlin Patricia , Happé Francesca 
Published: November 2020

AbstractLongitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50–60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. Overall, outcomes for autistic people are on average poor, and higher IQ appears to be protective against having a poor outcome. The limitations of current constructs of outcome are discussed.
Prospects for upgrading by the European kelp sector
Authors: van den Burg Sander , Selnes Trond , Alves Liliana , Giesbers Else , Daniel Ana 
Published: November 2020

AbstractThe interest in cultivating seaweed in European seas as source of food, feed and feedstock for the biobased economy is growing. Amongst the species investigated is kelp, also known as sugar kelp, Saccharina latissima or Laminaria saccharina. The European kelp sector is relatively small, compared to the global production and use, yet growth of the sector is aimed for. An inevitable question for European seaweed producers is how they can compete in the global seaweed value chain. This paper assesses to what extent the European strategy for growing the kelp sector matches with the dynamics of current kelp value chain. The global value chains (GVC) framework is applied to study how the global kelp sector is organized, including analysis of trends in science and patents. The upgrading strategy deployed by the European sector is critically evaluated against this framework. The analysis points towards various dividing lines between the established kelp cultivation and processing industry in Asia and the (far smaller) nascent cultivation and processing industry for high-value applications. These represent two unconnected worlds. Chain or intra-sectoral upgrading to spur the European kelp sector could occur if European food sector engage more closely with the European producers. Those bring financial power and a broader client base to the table and are instrumental in linking production to the demands of end-users.
Dynamical Phase Transitions for Flows on Finite Graphs
Authors: Gabrielli Davide , Renger D. R. Michiel 
Published: November 2020

AbstractWe study the time-averaged flow in a model of particles that randomly hop on a finite directed graph. In the limit as the number of particles and the time window go to infinity but the graph remains finite, the large-deviation rate functional of the average flow is given by a variational formulation involving paths of the density and flow. We give sufficient conditions under which the large deviations of a given time averaged flow is determined by paths that are constant in time. We then consider a class of models on a discrete ring for which it is possible to show that a better strategy is obtained producing a time-dependent path. This phenomenon, called a dynamical phase transition, is known to occur for some particle systems in the hydrodynamic scaling limit, which is thus extended to the setting of a finite graph.
Preferential Engagement and What Can We Learn from Online Chess?
Authors: Kulikov Vadim 
Published: November 2020

AbstractAn online game of chess against a human opponent appears to be indistinguishable from a game against a machine: both happen on the screen. Yet, people prefer to play chess against other people despite the fact that machines surpass people in skill. When the philosophers of 1970’s and 1980’s argued that computers will never surpass us in chess, perhaps their intuitions were rather saying “Computers will never be favored as opponents”? In this paper we analyse through the introduced concepts of psychological affordances and psychological interplay, what are the mechanisms that make a human-human (HH) interaction more meaningful than a human-computer (HC) interaction. We claim that an HH chess game consists of two intertwined, but independent simultaneous games—only one of which is retained in the HC game. To help with the analysis we introduce the thought experiment of a Preferential Engagement Test (PET) which is inspired by, but non-equivalent to, the Standard Turing Test. We also explore how the PET can illuminate, and be illuminated by, various philosophies of mind reading: Theory Theory, Simulation Theory and Mind Minding. We propose that our analysis along with the concept of PET could illuminate in a new way the conditions and challenges a machine (or its designers) must face before it can replace humans in a given occupation.
The Pragmatic and Stylistic Aspects of Communication Between State Authorities and the Citizen within e-Administration in Poland
Authors: Kowalczyk Joanna 
Published: November 2020

AbstractThis article discusses the specificity of remote communication between state authorities and citizens as part of e-administration services. Attention was paid to the available technological tools used in state-citizen communication (e.g. applications, help centres), but most of all, the focus was on the pragmatics of creating messages in the “digital office”. The aim of the present study was to identify the main linguistic and quasi-linguistic instruments that build the stylistic and pragmatic formula of e-administration in Poland. The source material was taken from the widely available and most popular e-administration platforms, containing detailed information on services provided by public administration and enabling the citizen to establish remote contact with the state, such as Obywatel.gov.pl, ePUAP.gov.pl, CEIDG.gov.pl and Biznes.gov.pl.
Perceptualism and the epistemology of normative reasons
Authors: Müller Jean Moritz 
Published: November 2020

AbstractAccording to much recent work in metaethics, we have a perceptual access to normative properties and relations. On a common approach, this access has apresentationalcharacter. Here, ‘presentational’ specifies a characteristic feature of the way aspects of the environment are apprehended in sensory experience. While many authors have argued that we enjoy presentations of value properties, thus far comparatively less effort has been invested into developing a presentational view of the apprehension of normative reasons. Since it appears that this view would offer much the same theoretical benefits as presentational views of the apprehension of value, it seems worthwhile redressing this imbalance. My paper aims at doing so, focusing on concern-dependent practical reasons. After clarifying the central commitment of this view, I assess a recent proposal by Dancy (Ethics 124(4):787-812, 2014) which provides a detailed characterization of the relevant type of cognition. I argue that Dancy ignores one of the central features of a presentational access to normative reasons and therefore misidentifies which actual psychological phenomena are apt to play this role. In this context, I also assess and reject further candidates that might seem fitting for this purpose. In the remainder of the paper, I then offer a more adequate account which specifies an actual form of presentational access to concern-dependent practical reasons and provide the contours of a more substantive account of its nature.