bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluación de las propiedades funcionales del aislado proteico de quinua (Chenopodium qui- noa Willd) variedad INIAP-TUNKAHUAN con potencial uso en la nutrición humana
Authors: Lozano Richy , Tapia C. Iván L. , Taco. T Verónica J. 
Published: January 2020

Introducción: La quinua es un alimento libre de gluten con alto potencial en la alimentación humana, ya que tiene alto valor nutricional, una propicia calidad proteica, cuyas propiedades funcionales son ideales para el desarrollo de nuevos productos alimenticios de alto valor agregado; sin embargo, estas pueden perderse durante el procesamiento.
Objetivo: Evaluar el efecto de dos procedimientos de aislamiento de proteínas de la harina integral de quinua ecuatoriana (variedad INIAP Tunkahuan) sobre las propiedades funcionales de los aislados proteicos de esta.
Métodos: El aislamiento proteico se realizó por solubilización / precipitación isoeléctrica, con y sin remoción de compuestos fenólicos, para prevenir efectos indeseables como el oscurecimiento y cambios en la digestibilidad del aislado proteico. A partir de la harina de quinua seca y desengrasada se solubilizó el contenido proteico a pH alcalino (9.0), luego se realizó una precipitación a pH ácido (5.0). La remoción de compuestos fenólicos se efectuó usando tratamiento ácido (pH 4.5) previo a su extracción. El potencial tecnológico en el aislado liofilizado fue evaluado a través de las propiedades funcionales
Resultados: La remoción de compuestos fenólicos provocó un oscurecimiento del aislado, disminución de la cantidad de proteínas, capacidad de retención de agua y tamaño de gota de la emulsión (propiedad emulsificante). Además, la capacidad espumante fue independiente del procedimiento usado, también el aislado proteico obtenido sin la remoción de compuestos fenólicos presentó mayor viscosidad
Conclusiones: Las proteínas de quinua pueden ser un ingrediente prometedor en la producción de alimentos funcionales, pero se necesita seguir estudiando las propiedades bioactivas de sus péptidos.
Síndrome HaNDL
Authors: Barros-Gutiérrez Camilo Ernesto , Silva-Monsalve Edwin , Gualtero-Trujillo Sandra 
Published: January 2020

Introducción: El Síndrome HaNDL (Headache and neurologic deficits with cerebroespinal fluid lymphocytosis) por sus siglas en inglés, es una patología que cursa con cefalea, focalización neurológica y linfocitosis en el líquido cefalorraquídeo. Objetivo: este artículo busca presentar un caso de Síndrome de HaNDL, puesto que esta condición nosológica implica un reto diagnóstico. Resultados y conclusiones: Se presenta el caso de un paciente con diagnóstico de síndrome de HaNDL los hallazgos al examen físico y del líquido cefalorraquídeo. [Barros-Gutiérrez CE, Silva-Monsalve E, Gualtero-Trujillo S. Síndrome HaNDL. MedUNAB 2015; 17(3): 190-192].
Modulations of Identities: A Regional Façade Design Resource from the Classicalised (Aristocratic) Vernacular
Authors: Kassim Puteri Shireen Jahn , Abdul Majid Noorhanita , Mohd Nawawi Norwina , Qarihah Tengku Anis 
Published: January 2020

The paper discusses and describes a range of templates, models and variations of tropicalised modulation of facades and recesses from in the local vernacular which convey an aesthetic sense of the region, to counter the homogeneity of modern facades. These range of identified Malay-Nusantara are abstracted from elevations of mansions and palaces which convey a sense of the Classical and which were identified as a new identified substyle of the vernacular. Operationally categorised as a form of Classical vernacular, they represent a rich range of models and templates arising from the region’s past ingenuities that can also transcend the present approach of merely adorining modern structures with Nusantara roofs into a more critical approach. The paper argues that these variations can constitue an untapped resources for creating the modulations of facades in any Nusantara-themes city of the future; without reverting to cosmetic application of motifs and cut-and -paste from the vernacular This language includes key attributes such as proportioned and regular spaces of columns, recesses, projections, staircases and balustrades which are fused in various ways to present a more critical trope of local identity that can be combined and permutate into a tropical ‘facadism’ with a differentiated and dirinctive identity for the south east Asia city in general and the Malay nusantara in particular.
The Art of Adaptation: From Folk Literature to the Age-Appropriate Visual Media
Authors: Sidhartani Santi , Qeis Muhammad Iqbal , Pratama Dendi 
Published: January 2020

The art of adaptation is a process to translate the art form fromone mediainto another.Folklores as a form of media that express the experience and beliefs that was shared amongst the society living in a certain region are usually passeddown from the older generation to the younger generation by word of mouth orthoughoral tradition. Althoughsome of thefolklores havebeen compiledand translated in the form of folk literature andare transcribedin books and written media, these folk literaturesgenerally consist oftexts with little visuals. This is a problem since the main target of folklores is usually children who are more attracted to colorful and rich world of illustration rather than a text-filled literary book. This paper aims to describe the process involved in the art of adaptation that transforms folk literature into a more age-appropriate visualmediaforchildren as an effort to preserve the tradition of folklore in society. The conclusion shows that the process involved a deep understanding of the folklore, not only the story but also the characters and the background location depictedin order to design an appealing visual media thatretainsthe cultural values shared within the society
Primary Salivary Gland Tumors- A two years study at Nobel Medical College
Authors: Nepal Niraj , Choudhary Prabesh Kumar , Das Manish Kumar , Basnet Meenakshi , Paudel Sagar 
Published: January 2020

Introduction: Salivary gland tumors are a heterogeneous group of neoplasms that are relatively rare but represent a wide variety of both benign and malignant histopathologic subtypes. The aim of this study was to find out the histopathological distribution of primary salivary gland tumors and correlate fine needle aspiration cytology reports with histological findings.Materials and Methods: A total of 83 patients attending the otorhinolaryngology department with salivary gland tumors were enrolled in our study. The histopathological findings were reported and correlated with cytological findings.Results: The mean age of the patient with salivary tumors was 43.11 ± 13.02 years. Out of 83 cases, 3 (3.6%) patients were diagnosed as inflammatory lesions, 64 (77.1%) patients had benign salivary gland tumors and 16 (19.3%) of patients had malignant salivary glands tumors in histopathology. The sensitivity and specificity of FNAC in this series for detecting salivary gland malignancy were 68.8% and 98.5% respectively with an overall diagnostic accuracy of 92.8%. The most common salivary gland tumor was found to be pleomorphic adenoma (56.6%) and the most common malignant salivary gland tumor was found to be mucoepidermoid carcinoma (19.3%). The comparison of the incidence of salivary gland tumors in various age groups showed a statisticallysignificant difference (p=0.009).
Conclusions: Benign salivary tumors are more common than malignant tumors with the most common occurrence in parotid glands. Pleomorphic adenoma is the most common benign tumor whereas; mucoepidermoid carcinoma is the most common malignant tumor in patients visiting Nobel medical college.
Epidemiological Profile and Determinants of Tuberculosis in Urban Nepalese Population
Authors: Bhatta Subash , Pant Nayana 
Published: January 2020

Introduction: Tuberculosis has evolved through ages to remain a major cause of morbidity and mortality worldwide. Despite having a very successful Directly Observed Treatment, Short-course program, tuberculosis is still one of the most widespread infections in Nepal. This study was done to observe the epidemiological profile of tuberculosis patients in an urban Nepalese population.Materials and Methods: 585 newly diagnosed cases of pulmonary and extrapulmonary tuberculosis in two tertiary level hospitals in the country were enrolled in the study during a period of 18months. A standard questionnaire was formatted and the required information was acquired with the help of interview and investigation reports.Results: The mean age of presentation was 35.76 with a male to female ratio of 1.48:1.57% of the cases had less than primary education with 26 % being illiterates. The most commonly involved occupational group was farmers (22%) followed by students (20%) and laborers (14%). 22% of cases had a history of contact with tuberculosis in the family. 41 % were smokers and 18 % abused alcohol. Pulmonary tuberculosis comprised 68% of the total cases. The most common extrapulmonary presentation was lymph node TB (28%) followed by pleural effusion (21.5%) and tubercular meningitis (16%).Conclusions: Young people with lower literacy levels and with a family history of tuberculosis are at increased risk of acquiring tuberculosis and community approaches for tuberculosis control should target this group to reduce the burden of the disease
An Unusual Case of Wart-like Presentation of Ocular Surface Squamous Neoplasia
Authors: Shrestha Nirsara , Shrestha Sangeeta , Shrestha Arjun 
Published: January 2020

The ocular surface squamous neoplasia refers to the entire spectrum ranging from mild to severe dysplasia to carcinoma in situ and invasive squamous cell carcinoma. Ocular surface squamous neoplasia may present clinically in various ways: gelatinous, velvety or papilliform or leukoplakic. This case report describes a 50-year-old male who presented with a filiform wart-like appearance of conjunctival mass unlike described earlier. Excisional biopsy was done and histopathology revealed intraepithelial neoplasia with high-grade dysplasia.
Antibiogram and Biofilm Formation among Carbapenem Resistant Klebsiella pneumoniae
Authors: Pradhan Roshani Nhuchhen , Madhup Surendra Kumar , Pant Shyam Prasad 
Published: January 2020

Objectives: This cross-sectional study was designed to detect the carbapenemase producing K. pneumoniae along with biofilm producers from different clinical specimens and to compare antibiotic susceptibility pattern of biofilm producing carbapenem resistant Klebsiella pneumoniae and biofilm non-producing carbapenem resistant Klebsiella pneumoniae.
Methods: A total of 1475 non-repetitive clinical samples were included on this study. Antibiotic Sensitivity Testing (AST), Modified Hodge Test (MHT) and Modified Carbapenem inactivation method (mCIM) were performed for detection of carbapenemase production and Congo red agar method (CRA) along with Microtitre plate method were performed for detecting biofilm production.
Results: Among the clinical specimens cultured, growth positivity was 62.71%. E. coli was most predominant organism followed by K. pneumoniae (17.89%). Among the 110 K. pneumoniae, 57 were found to be carbapenemase producer. Majority of the carbapenemase producing K. pneumoniae were isolated from sputum (45.61%), in the specimen collected from age group 61-70 (28.07%) and in out-patient department (50.88%). Similarly, 65.45% K. pneumoniae out of 110 were found to be biofilm producer by Congo red agar method while among those 72, 73.59% isolates were found to be quantitatively biofilm producer in Microtitre plate assay. Out of 57 carbapenemase producer, 35.08% were strongly biofilm producer while among 53 carbapenemase non-producer 30.18% were strongly biofilm producer from Congo red agar method. Moreover, Microtitre plate assay evidenced that, out of 57 carbapenemase producer, 40.35% were highly biofilm producing and among the 15 carbapenemase nonproducer 66.66% were highly biofilm producer.
Conclusion: Biofilm formation is highly prevalent with varying degree of resistance among different antibiotics including carbapenems that further augments antibiotic resistance. The study showed carbapenemase producers are stronger biofilm producer than the non-carbapenemase producer. Therefore, it is recommended to identify biofilm formation among carbapenemase producers for effective choice of antibiotics.
Comparison of Biofilm Producing and Non-Producing Escherichia coli Isolated from Urine Samples of Patients Visiting a Tertiary Care Hospital of Morang, Nepal
Authors: Tumbahangphe Manita , Shrestha Bijay Kumar , Shakya Jenish , Khanal Hemanta 
Published: January 2020

Objectives: The main objective of this study was to determine the prevalence of Escherichia coli among urinary tract infection (UTI) suspected patients visiting tertiary care hospital and to assess the biofilm producing ability of E. coli isolates.
Methods: A prospective cross-sectional study was carried out in Biratnagar Metropolitan city, Eastern Nepal from December 2018 to May 2019. During the study 400 urine samples were collected from UTI suspected patients visiting a tertiary care hospital of Biratnagar. Urine samples were cultured by using semi-quantitative culture technique and identified. Antibiotic susceptibility testing was done by Kirby-Bauer Disk Diffusion method according to CLSI (2011) guidelines. Biofilm assays were performed by microtitre plate method.
Results: This study reported 15% prevalence of E. coli out of 400 urine samples. 100% of E. coli isolates showed resistance to both Ampicillin and Amoxicillin while 100% were sensitive to Chloramphenicol. 70% (42/60) isolates were Multi Drug Resistance (MDR)E. coli. The maximum isolates (86.66%) were found to be biofilm producers by microtitre plate method. Resistance to other antibiotics such as Nalidixic acid (71.11% vs 46.66%), Norfloxacin (53.33% vs 46.66%), Cotrimoxazole (42.22% vs 26.66%) was comparatively higher among biofilm producers than non-biofilm producers. There was a significance of association between biofilm and MDR (p<0.05).
Conclusion: There is relation between the ability of biofilm formation and drug resistance in the bacterium resulting to the failure of antibacterial drugs.
Effective use of Penicillin to Improve Culture Yield for Mycobacterium tuberculosis
Authors: Pradhan Sneha , Ghimire Gokarna Raj , Shrestha Shova 
Published: January 2020

Objective: To compare LJ media and LJ media with penicillin for the growth of Mycobacterium tuberculosis and contamination, in pulmonary tuberculosis (PTB) suspected patients.
Methods: A total of 300 PTB suspected cases at National Tuberculosis center (NTC) for analyzed for culture and contamination. Early morning sputum samples were collected in sterile leak-proof falcon tube. Digestion, decontamination and homogenization of sputum were done using NALC-NaOH (Modified Petroff method). The sputum sample was processed on LJ media and penicillin added LJ media and incubated at 37. Cultures were examined after 8 weeks.
Results: All the PTB suspected cases were compared in LJ media and LJ media with penicillin, 29.7% (89) were positive, 21% (63) were contaminated on LJ media whereas 41% (123) were positive, 3.7 % (11) were contaminated on penicillin added LJ media. Also, 25 (8%) were 1+ grading, 14 (4.7%) were 2+ grading, whereas 81 (27%) and 45 (15%) were 3+ grading LJ + Penicillin and LJ media respectively.
Conclusion: Contamination was reduced by 17.3% with the addition of penicillin to LJ media. And isolation of total positive cultures was enhanced by 11.3%.
Urinary Tract Infection among Patients Visiting Ganesh Man Singh Memorial Hospital and Research Center, Lalitpur, Nepal
Authors: Dhungana Janak Raj , Budhathoki Aruna , Poudel Goma , Basnet Jyotika , Shah Ravi 
Published: January 2020

Objectives: The objective of this study was to determine the prevalence of urinary tract infection (UTI) and antibiotic sensitivity pattern among the suspected UTI cases visiting at Ganeshman Singh Memorial Hospital Lalitpur, Nepal.
Methods: A total of 300 mid-stream urine, catheter and suprapubic aspirate from UTI suspected patients were included and processed for routine microscopy and culture and then identified by standard microbiological methods. Antibiotic susceptibility test was performed by Kirby- Bauer disc diffusion method.
Results: Out of 300 samples, 55(84.6%) mid-stream urine and 10(15.4%) catheter sample had significant bacterial growth. E. coli (32,49.2%) was the most common isolate followed by Staphylococcus aureus (10,15.3%), Enterobacter spp. (8,12.3%), Klebsiella spp. (7,10.7%), Pseudomonas aeruginosa (3,4.6%), Proteus spp. (3,4.6%), Acinetobacter spp. (1,1.5%) and Enterococcus spp. (1,1.5%). Most of the Gram-negative bacterial isolates were sensitive to Ceftriaxone (88.8%) followed by Gentamicin (72.2%), and Nitrofurantoin (64.8%) and resistant to Amoxicilin (68.5%) followed by Nalidixic Acid (53.7%). Gram positive isolates were sensitive to Amikacin (72.7%) followed by Imipenem (63.6%) and Gentamicin (63.6%) whereas resistant to Amoxycilin (72.7%) and Ciprofloxacin (63.63%).
Conclusion: The main cause of the UTIs was found as Gram negative bacteria. Prescription of antibiotics based on susceptibility tests would help in reduction of antibiotic resistance.
Microorganisms for Improved Crop Production and Better Human Health in Nepal
Authors: Banjara Megha Raj 
Published: January 2020

In 2018, Nepal’s 27.6% gross domestic product is contributed by agriculture. The agricultural practices in the country are traditional and productivity is not an optimum level as expected. Nepal imports agricultural products of about Rs. 80 billions from the other countries. Current agricultural practices in Nepal depend on chemical fertilizers and pesticides. These chemicals have deleterious effects on nutritional value of crops and farmers and to consumers. Further, these chemicals in agriculture have resulted adverse effect on ecology, environmental contamination, accumulation of these toxic compounds in soil. These have led a demand for technologies of improving both the quantity and quality of agricultural products. To meet the demand of the growing population, the productivity need to be increased significantly.
There are very limited industries in Nepal producing biopesticides, microbial biofertilizers that can be used for increased agricultural production. Biofertilizers, biopesticides, and biocontrol agents are the alternatives to chemical agents. Microorganisms applied to soil or plant improve the productivity. These microorganisms are natural and widely used to control pests and protect human health. Microbial inoculants such as bacteria, fungi, virus and algae which are environment-friendly and can be used in sustainable manner. Therefore, farmers should be made aware of these microbial technologies and academic sector should be involved to develop these agents. Government sector, academia and industry collaboration in public private partnership model could help to move these activities further.
Vernetzte Produktionsplanung
Authors: Ellwein Carsten , Elser Anja 
Published: January 2020

Kurzfassung
Der aktuelle Trend der Vernetzung von Unternehmen im produzierenden Sektor zu temporären Produktionsnetzwerken stellt neue Anforderungen an die Produktions- und Ressourcenplanung. Um effizient flexible Wertschöpfungsnetzwerke aufzubauen, bedarf es einer einfachen Methode, um Produktionspartner zu finden. Die Partnerauswahl kann nur dann optimal gestaltet werden, wenn deren Ressourcen schon in der Planungsphase zur Verfügung stehen. Die Vernetzung von Produktionsplanungs und -steuerungssystemen (PPS-Systeme) ist eine Möglichkeit, Ressourcen über Unternehmensgrenzen hinweg zur Verfügung zu stellen. Das dabei entstehende Netzwerk von PPS-Systemen stellt neue Herausforderungen. Zum einen ist eine einheitliche Beschreibung von Produktionsaufträgen inklusive benötigter Ressourcen und deren Fähigkeiten die Basis der beschriebenen Vernetzung. Zum anderen muss eine Architektur entwickelt werden, die es erlaubt, fremde Ressourcen mit in den Planungsprozess mit einzubeziehen. So wird aus dem bisherigen, lokalen Planungs- und Optimierungsprozess eine globale Ressourcenplanung.
Produktionsnetzwerke und Fabriktypen der Zukunft
Authors: Lanza Gisela , Häfner Benjamin , Verhaelen Bastian , Peukert Sina 
Published: January 2020

Kurzfassung
Die zunehmende Globalisierung führte in den letzten Dekaden zu global verteilten Produktionsnetzwerken. Um solche Netzwerke und die darin befindlichen Fabriken auf strategischer Ebene auszurichten, haben sich idealtypische Modelle bewährt, die als Leitlinien einer fundierten Fabrik- und Netzwerkorganisation zu verstehen sind. Dieser Beitrag beschäftigt sich mit solchen idealtypischen Modellen und zeigt exemplarisch auf, wie sie sich für das Management globaler Produktionsnetzwerke einsetzen lassen.
Synthesis of nanosized cadmium ferrite and assaying its magnetic and dielectric properties by analytical and physical techniques
Authors: Dubey Hemant Kumar , Lahiri Preeti 
Published: January 2020

Abstract
Our goal is to investigate the physical, magnetic and dielectric properties of cadmium ferrite nanoparticles. Here we report the synthesis of nanosized cadmium ferrite (CdFe2O4) spinel ferrite by the sol-gel process using citric acid as a complexing agent. We assessed the properties of nano-CdFe2O4 by a variety of analytical and physical techniques. X-ray diffraction and Fourier transform infrared spectroscopy were performed to confirm spinel phase formation. Surface morphology images and compositional features were obtained using electron microscopy and other imaging techniques. Transmission electron microscopy analysis revealed the formation of nanoparticles with an average particle size of 40 nm. The magnetic properties were characterized by a highly sensitive magnetometer system (SQUID VSM) at room temperature revealing that the sintered sample of cadmium ferrite nanoparticles is ferromagnetic. We also studied dielectric behavior of the sintered pellet of the sample. We determined the frequency dependence of the dielectric permittivity, the loss factor and the impedance of the samples in the frequency range from 100 Hz to 20 MHz, at temperatures from 308–428 K at an interval of 40 °C. The dielectric behavior of ferrites is explained by the interface polarization, arising from the heterogeneous nature of its structure. Further research, both in terms of the preparation and characterization of ferrites, is warranted to better understand the nature and application of ferrites.