bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alterations of serum high sensitive C reactive protein and lipid levels in newly diagnosed myocardial infarction subjects
Authors: Aparna R. R. , Rajeswari D. Raja , Ramalingam K. , Kumar R. Viswa , Balakrishna D. 
Published: November 2019

Background: Acute Myocardial Infarction (AMI) is one of the major causes of mortality in the world. Atherosclerosis leading to AMI is the most common and severe clinical manifestation observed. Dyslipidemia is one of main traditional risk factor for MI, but in more than 50% of CHD events dyslipidemia was absent. Atherosclerosis is considered as both a chronic inflammatory condition and a disorder of lipid metabolism. The present study was aimed to estimate the levels of serum lipids (total cholesterol, LDL cholesterol, HDL cholesterol) and hs-CRP an inflammatory marker in newly diagnosed AMI cases and to find out any correlation between these two.Methods: The study was conducted on 50 newly diagnosed myocardial infarction cases, admitted in Cardiology Department Narayana Medical College, Nellore. Both the sexes were included. Fifty age and sex matched healthy individuals were selected as controls. Lipid levels are estimated by end point colorimetric assay (HUMANSTAR kit) and hs-CRP was estimated by immunofluorescence technique (Boditechkit).Results: Significant raised levels of hs-CRP (p value <0.0001) and low HDL cholesterol (p value =0.0085) levels among the cases was noticed. A significant positive correlation was observed between LDL cholesterol and hsCRP (r=0.109, p=0.040). A non-significant positive correlation between hsCRP and HDL cholesterol (r=0.291, p=0.453) was observed.Conclusions: The results of the study implicate the role of inflammatory component in causing atherosclerosis or coronary artery disease rather than dyslipidaemias alone to be attributed for atherogenesis. Concomitantly HDL cholesterol levels were found to be low in cases that results from the inflammatory component in atherogenesis.
Percutaneous nephrostomy, feasibility of mid and anterior axillary line approach and its complications: an experience
Authors: Sundaram Senthilnathan , Balasubramanian Jayamurugan , Narayanasami Mohan Babu , Vanga Rajitha 
Published: November 2019

Background: Nephrostomy performed as an emergency procedure to drain the obstructed calyceal system is a lifesaving procedure. Posterolateral approach is usually done to access the avascular plane of Brodel to avoid hemorrhage. This study evaluates the feasibility and complications in percutaneous nephrostomies placed at mid and anterior axillary line entry sites as it was found to be easier approach.Methods: A prospective study with 126 percutaneous nephrostomies performed with Ultrasound guidance, using single puncture technique and 8.5F pigtail catheter. The complications rates were analyzed according to WHO guidelines. Results: The technical success rate was 98.4%. Three hemorrhagic complications (2.38%) were recorded without any major interventions. Increased incidence (11.9%) of transient hematuria was observed with five cases (3.9%) of infection at entry site. One case (0.79%) of peritoneal breech recorded with no significant intraperitoneal collection. Conclusions: Placement of Percutaneous Nephrostomy tube at mid or the anterior axillary line appears to be a feasible and easy approach, as its complications rates are within acceptable limits with an advantage of increased patient comfort.
Proposing a Gaming Language Analysis Procedure to Reveal Video Game Ideology through Ludic Linguistics
Authors: Purnomo SF Luthfie Arguby , Khristianto Khristianto 
Published: November 2019

This study proposes a procedural analysis on the implementation of ludic linguistics to analyze gaming language with wordplays, the core of focus in ludic linguistics, as the point of departure. To formulate the procedural analysis, theories of language play by Crystal ideology of influence and ludonarrative model by Aarseth, wordplay in gaming context by Paul, intended meaning level by Stiles, wordplay transmission by Winter-Froemel, game interface types by Stonehouse and indexical storytelling by Fernández-Vara were applied as the theoretical foundation. To provide a vivid application of the proposed procedural analysis, wordplays appearing on game assets from Konami’s Metal Gear Solid, Metal Gear Solid 2: Sons of Liberty, and Metal Gear Solid 3: Snake Eater were taken as examples of analysis. The five steps procedure is able to show how wordplays in gaming context are designed as mechanical cues to help gamers complete the games and as narrative cues to help them comprehend the story. Further, this proposed procedure is able to indicate that the mechanical and narrative cues have particular ideology of influence, which affects gamers in reacting and responding to particular problems presented by the games. The result of this study discloses future research on the roles of wordplays in gaming context, signifying the importance of ludic linguistics as a bridge between language studies and game studies. Keywords: Wordplay; Gaming Language; Ludic Linguistics; Game Dtudies; Metal Gear Solid
An evaluation of mean platelet volume, sedimentation, and crp in brucellosis patients
Authors: PARLAK Emine , ALAY Handan , KESMEZ CAN Fatma , PARLAK Mehmet , KOŞAN Zahide 
Published: November 2019

Aim: Brucellosis is an important infectious disease in
Turkey and our region. Mean platelet volume(MPV) is a marker of platelet
function, production, and activation. The purpose of this study was to evaluate
the relation between epidemiological characteristics of brucellosis patients
and MPV and other inflammatory markers.Material
and Methods: Brucellosis
patients hospitalized for monitoring at the Infectious Diseases Clinic in
2007-2015 were included in the study. One hundred patients with positive tube
agglutination tests and/or with bone marrow culture growth, and 100 controls group
without diagnosis of brucellosis were enrolled. Patients’ MPV, sedimentation,
and CRP values were compared with those of the controls. Results: Men constituted 64% of the patients were men, and the
mean age of the patient group was 37.33±16.88
years. The control group consisted of 62% men, with a mean age of 40.35±15.46.
There was no statistically significant difference between patients and controls
in terms of age or sex. CRP, MPV, and sedimentation were significantly higher
in patients with brucellosis than in the controls.

Conclusion:
MPV is novel, low cost, easily applied marker. It may
be of greater value when assessed together with other inflammatory markers. Our
findings suggest that MPV values may be a useful inflammation marker and
prognostic factor in brucellosis patients.
Akciğerin büyük hücreli nöroendokrin karsinomundaki cerrahi sonuçlarımız
Authors: YANIK Fazlı , KARAMUSTAFAOĞLU Yekta Altemur , YORUK Yener 
Published: November 2019

Giriş/Amaç: Akciğerin büyük hücreli
nöroendokrin karsinomları (BHNK) yüksek dereceli nadir tümörlerdir ve küçük hücreli akciğer kanserine
benzer klinik ve biyolojik özellikler taşırlar. Bu çalışmada histopatolojik
tanısı akciğerin BHNK’u olan olgulardaki cerrahi sonuçlarımızı, prognozu ve
sağkalımı irdeledik.

Materyal-Metod:
Haziran 2012-Haziran
2018 tarihleri arasında rezeksiyon yapılan ve patolojik tanıları BHNK olarak
raporlanan biri kadın, 11’i erkek, ortalama yaşları 61,4±7,5(48-74 yaş) olan 12
olgu retrospektif olarak değerlendirildi. Prognoz, yaş, cins, sigara içme
hikayesi, tümör çapı, tanı tedavi modaliteleri, cerrahi sonuçlar ve sağkalım
hastane kayıtlarından analiz edildi.

Bulgular:
Sekiz olguda tümör
sağ hemitoraks yerleşimli iken, dört olguda sol hemitoraks yerleşimliydi. 11
olguda mediastinoskopi ve anatomik akciğer rezeksiyonu ile mediastinal lenf
nodu diseksiyonu uygulandı. T1 evreli bir olgu ise bilgisayarlı toraks
tomografisinde mediastende patolojik lenf nodu olmadığı için, mediastinoskopi
yapılmadan, video yardımlı lobektomi ve mediastinal lenf nodu diseksiyonu
uygulandı. Olguların yedisi (%58) takipler sırasında metastaz veya tümör progresyonu
nedeniyle kaybedildi. Ortalama tümör çapı, ortalama sağ-kalım süresi,
hastalıksız sağ-kalım süresi ve ortalama hastanede kalış süresi sırasıyla;
4,4±2,1 cm (dağılım 1-8 cm), 17,9±19,04 ay (dağılım 2-72 ay), 15,08±19,6 ay (
dağılım 1-72 ay ) ve 6,4±3,6 gün (4-12 gün) olarak hesaplandı. Postoperatif
mortalite görülmedi. İki(%16) olguda komplikasyon (atelektazi ve yara yeri
enfeksiyonu) görüldü.

Sonuç:
Tedavi ve sağ-kalım
açısından küçük hücreli akciğer kanserine benzer özellikler taşısa da, tedavi
stratejisinde tam olarak bir fikir birliğinin sağlanamamıştır. Günümüzde küratif
anatomik rezeksiyonlar ve beraberinde eklenecek onkolojik tedaviler uzun dönem
sağ-kalım için tek şans gibi gözükmektedir. Ancak bu nadir görülen tümörlerle
ilgili daha geniş vaka serilerini içeren çalışmalara ihtiyaç vardır.
Of Grim Witches and Showy Lady-Devils: Wealthy Women in Literature and Film
Authors: Schuchter Veronika 
Published: November 2019

Imagining super rich women in the real and fictional world has long been a struggle. Those few depictions that do exist are scattered across time periods and literary genres, reflecting the legal restrictions that, at different points in time, would not allow women to accumulate assets independent of the patriarchal forces in their lives. The scarcity of extremely wealthy women in literature and film is confirmed by Forbes magazine’s list of the fifteen richest fictional characters that features forty different fictional men and only nine women, with never more than two female characters nominated in a single year.
This article explores the depiction of three exceptionally wealthy women: Cruella de Vil in The Hundred and One Dalmatians (1956) by Dodie Smith, Miss Havisham in Great Expectations (1861) by Charles Dickens, and the figure of the stepmother in various adaptations of “Cinderella.” I demonstrate how the protagonists’ wealth allows them to manipulate others and disconnect themselves from patriarchal and societal expectations. Further, I argue that these affluent antagonists are “rogued” by their respective narratives, highlighting their perceived anti-feminine and emasculating behaviour resulting in a mode of narration that greedily gazes at and shames their appearances and supposed unattractiveness. While this genealogy of rich rogues reiterates the narrow scope of imagining wealthy women on the page and on the screen, there are moments in the narratives that disrupt stereotypical depictions of these wealthy characters who defy the labels imposed on them.
RELEVANSI BUDAYA “ NATING” DAN PERSEPSI MASYARAKAT KABUPATEN LAHAT TERHADAP POTENSI PENDIRIAN BAITUL MAAL WAT TAMWIL
Authors: Erdah Litriani 
Published: November 2019

Praktek gadai atau nating yang sering terjadi dimasyarakat dapat dikatakan terdapat unsur penganiayaan,hal ini disebabkan karena pelaku nating sangat terpaksa untuk menggadaikan lahan milik mereka, selama dalam masa perjanjian pemilik lahan tidak memiliki hak untuk mengelola atau menggarap dan tidak mendapatkan bagian dari hasil produksi atau hasil panen. Kemudian, pada saat perjanjian berakhir pemilik lahan harus menebus lahan dengan jumlah atau besaran yang sama pada saat peminjaman awal tanpa mendapatkan bagian dari keuntungan hasil panen itu sendiri. Budaya nating yang ada dimasyarakat selama ini telah berlangsung sejak lamadan menjadi adat yang biasa dan belum ada problem solving baik dari Pemerintah, lembaga adat atau pihak terkait lainnya. Konsep BMT (Baitul Mal wat Tamwil) dapat dihadirkan di daerah kabupaten kota Lahat Sumatera Selatan dan bahkan di kecamatan dan perdesaan.Konsep BMT sebagai lembaga keuangan mikro syari’ah. Pendekatan Community Based Riset (CBR) dilakukan dengan cara wawancara mendalam kepada masyarakat yang melakukan kegiatan nating, guna menemukan faktor-faktor yang melatarbelakangi masyarakat melakukan kegiatan nating tersebut dan permasalahan yang sering dihadapi . Wawancara dilakukan dengan pemilik tanah / lahan, pemilik modal, dan pemangku setempat yang berwenang baik pemangku pemerintahan maupun pelaku adat. Serta, mendiskusikan solusi yang tepat bagi masalah-masalah yang sering terjadi. Hasil dari penelitian ini didapatkan bahwa Masyarakat melakukan praktek nating atau gadai dikarenakan ada keperluan yang sangat mendesak biasanya untuk biaya pengobatan, biaya pendidikan anak, tambahan uang untu merenovasi rumah, tambahan uang untuk membeli kebun, banyak alasan yang melatarbelakangi masyarakat melakukan praktek gadai. Persepsi masyarakat mengenai keberadaan BMT sangat setuju karena dapat membantu masyarakat khususnya masyarakat yang sawahnya sudah tergadai, jenis BMT/ Koperasi yang diinginkan oleh masyarakat adalah jenis simpan pinjam yang tidak berbunga, serta pembayaran yang dapat dibayar pada saat musim panen. Relevansi budaya nating terhadap potensi pendirian BMT, bahwa diharapkan BMT menjadi suatu penewaran baru bagi permsalahan yang ada selama ini. Dengan danya pendiirian BMT diharapkan mampu menjadi sebuah solusi baru bagi permasalahan yang ada dimasyarakat. Pendirian BMT sangat relevan bagi solusi permasalahan budaya “nating” di Kabupaten Lahat pada umumnya.
Relationship between Work Climate and Physical Workload with Work-Related Fatigue
Authors: Mustofani Mustofani , Dwiyanti Endang 
Published: November 2019

Introduction: Work-related fatigue is a common problem in the workplace that must be solved because it has an impact on the occurrence of workplace accidents, reduces productivity and affects workers’ health. A survey conducted by the National Safety Council on 2010 workers in 2017 stated that 69% of them experienced work-related fatigue and 13% of them could be attributed to workplace accidents. Other studies conducted by O'Neill and Panuwatwanich in 2013 stated the loss that could arise due to work-related fatigue is averaged around $ 1,000/week. The purpose of this study was to determine the relationship between work climate and physical workload with work-related fatigue on workers in the 5th warehouse of fabrication area of Bangun Sarana Baja Company. Metods: This study is an observational analytic with a cross-sectional approach with 30 respondents who were randomly selected using the simple random sampling method. Measurements of the work climate used heat stress apparatus by calculating the Wet Bulb Globe Temperature, and measurement of physical workload is carried out by observations referring to Indonesian national standard No. 7269 in 2009. Meanwhile, work-related fatigue is measured objectively by using reaction timer. Results: This study indicates the average work climate is exceeding TLV (28.4° C), and the majority of workers got a moderate physical workload (53.3%) and experience mild work-related fatigue (50%). Conclusion: There was no relation between work climate and work-related fatigue (p-value = 0.192) and there was a significant relationship between physical workload and work-related fatigue (p-value = 0.028, r = 0.400). Keywords: physcal workload, work climate, work-related fatigue
The Influence of Noise Intensity and Age to the Employees’ Blood Pressure at Heavy-Duty Shop and EHS Department
Authors: Megananda Achmad Fachrul , Suwandi Tjipto 
Published: November 2019

Introduction: Noise is an unwanted sound heard by the hearers, which can trigger health problems if it continues to be exposed to a certain intensity. One of the health problems that can arise due to noise is the blood pressure increase. This study aims to analyze the influence of noise intensity and age to the blood pressure increase. Methods: This study was an observational study completed with cross-sectional design and analytics. The independent variables in this study were the noise intensity and age, while the dependent variable was the blood pressure. The sample collection of this study applied the total sampling method with 46 employees as respondents, i.e., 29 employees of the heavy-duty shop and 17 employees of the EHS Department in PT. Vale Indonesia. The data analysis was conducted by using the logistic regression statistical test with α-value of 0.05. Results: the noise intensity affected the increase of both systolic blood pressure (significance/p-value=0.00) and diastolic blood pressure (significance/p-value=0.01) with an odds ratio of the increase of systolic blood pressure (Exp (B) =9.75) and the increase of diastolic blood pressure (Exp (B)=5.76). Furthermore, the variable of age does not influence the increase of both systolic (significance/p-value=0.57) and diastolic (significance/p-value=0.41) blood pressures. Conclusion: the rise of the blood pressure of the employees is affected by the noise intensity factor in the workplace. Keywords: noise intensity, age, blood pressure
Analysis on Factors Causing Fatigue among Steel Casting Workers at PT X Sidoarjo
Authors: Jauhari Muhammad Amin 
Published: November 2019

Introduction: Fatigue is a common condition among workers as a protective mechanism to prevent their body from further damage. PT. X Sidoarjo is a company engaged in the manufacture of steel and wire rod. In the steel casting division, the workers experienced some fatigue. The steel casting workers experience a hot work climate since their work area was close to the billet burner furnace. The physical workload of the workers also affected the level of fatigue. Individual factors and sleep quality also affect the level of individual fatigue. The purpose of this research is to analyze the factors associated with fatigue among steel casting workers at PT. X Sidoarjo. Metods: This research is categorized as analytical observational research using the cross-sectional approach. The population of this study was 43 workers in the steel casting division at PT. X Sidoarjo. The sample of this research was 30 respondents based on simple random sampling method. The independent variables were individual factors, physical workload, work climate, and sleep quality; while the dependent variable was fatigue. Results: The results showed that there was a significant relationship between physical workload, work climate, and sleep quality with fatigue. There was no significant relationship between individual factors and fatigue. Conclusion: This research conclude that excessive workload, work climate, and poor sleep quality can cause fatigue among steel casting workers at PT. X Sidoarjo. Keywords: fatigue, personal factors, physical workload, sleep quality, work climate
Kedudukan Persekutuan Komanditer (Commanditaire Venootschap) Sebagai Corporate Guarantee
Authors: Abhimantara Ida Bagus 
Published: November 2019

Dalam tulisan ini penulis menyajikan suatu perspektif hukum dalam lembaga jaminan perorangan atau disebut sebagai borgtocht. Commanditaire vennootschap (CV) yang berposisi sebagai badan usaha yang tidak berbadan hukum mengambil posisi sebagai corporate guarantee dalam perjanjian accesoir dari perjanjian pokoknya, maka perlu dikaji keabsahan dan kewenangan badan usaha tersebut untuk melakukan tindakan hukum sebagai penanggung utang Debitor. Permasalahan yang dibahas dalam tulisan ini mengenai kedudukan CV selaku corporate guarantee dalam perjanjian penanggungan dan keabsahan CV menjadi penanggung dalam suatu perjanjian penanggungan. Isu-isu hukum yang dikemukakan dalam tulisan ini menyimpulkan bahwa CV yang merupakan badan usaha tidak berbadan hukum tidak dapat berposisi sebagai corporate guarantee atau borgtocht karena dalam ketentuan jaminan perorangan pada Pasal 1820 Burgerlijk Wetboek yang dapat menjadi penanggung adalah subjek hukum baik badan hukum (recht persoon) maupun orang perorangan (naturlijk persoon) dan CV sebagai badan usaha tidak memiliki kewenangan bertindak (bevoegheid) dan perjanjian penanggungan tersebut dapat dibatalkan (vernietigbaar) karena tidak memenuhi unsur subyektif dalam Pasal 1320 BW.
Biodegradation of recalcitrant compounds and phthalates by a consortium of Liometopum apiculatum gut microbiota
Authors: González-Escobar Jorge L. , Pereyra-Camacho Marco A. , Léon-Rodríguez Antonio De , Grajales-Lagunes Alicia , Reyes-Agüero Antonio , Chagolla-López Alicia , Rosa Ana Paulina Barba de la 
Published: November 2019

Abstract
The authors have withdrawn this preprint from Research Square
TNFα drives the proliferation and inflammatory response, but not regenerative potential of Müller cells in the mouse retina
Authors: Niu Lianglaing , Fang Yuan , Yao Xiaoqian , Zhang Yi , Wu Jihong , Chen Dong Feng , Sun Xinghuai 
Published: November 2019

Abstract
Background Mouse Müller cells, considered dormant retinal progenitors, respond to retinal injury by undergoing reactive gliosis rather than displaying regenerative responses. Tumor necrosis factor alpha (TNFα) is a key cytokine induced after injury, and implicated in mediating inflammatory and regenerative responses. However, the molecular events driving reactive gliosis and regenerative responses in Müller cells, and the role of TNFα in these processes, remain unclear. In this study, we investigated the effects of TNFα on Müller cell responses following injury. Methods To investigate the involvement of TNFα in retinal injury, adult C57BL/6J mice were subjected to treatment with light (5,000 lux) for 14 consecutive days; induction of TNFα was confirmed by quantitative polymerase chain reaction (qPCR). TNFα effects on Müller-cell proliferation were evaluated via 5-ethynyl-2’-deoxyuridine (EdU) incorporation in culture. TNFα-mediated gene profile changes were examined using Affymetrix microarray, and gene ontology analysis was carried out to define the molecular pathways involved. Gene- and protein-expression changes were further verified by qPCR, western blot, and enzyme linked immunosorbent assay (ELISA). Results We showed that TNFα induced Müller cell proliferation and the expression of inflammatory and proliferation-related genes, including NFKBIA, Leukemia inhibitory factor, Interleukin-6, Janus kinase (Jak) 1, Jak2, Signal transducer and activator of transcription (Stat) 1, Stat2, Mitogen-Activated Protein Kinase (MAPK) 7, and MAP4K4. Blockade of Jak/Stat and MAPK pathways attenuated TNFα-induced Müller cell proliferation. Moreover, we detected TNFα drove A1 phenotype-reactive gliosis, while Wnt attenuated TNFα-mediated induction of A1 phenotype and promoted an A2-like phenotype. Conclusion In Müller cells, TNFα triggered primarily inflammatory and reactive gliosis by activating Jak/Stat and MAPK-pathways without inducing progenitor cell/regeneration-related genes. Wnt signaling suppressed inflammation, and induced proliferation and expression of progenitor-cell genes in Müller cells. These results suggest that reactive gliosis and regenerative responses in Müller cells are regulated by independent mechanisms. Our study provides new insights into regulation of inflammatory and regenerative responses of Müller cells in the injured retina
Metaphor Analysis on Color Lexicon with Plant Attributes in Madurese Language
Authors: Fadhilah Nurul , Rais Wakit Abdullah , Purnanto Dwi 
Published: November 2019

The research aimed to describe the Madurese color lexicons with plant attributes and to analyze those lexicons metaphorically. This research engaged 18 informants to denote Madurese color lexicons by showing 139 color cards. The referential comparison method was followed by sorting the decisive element technique through referential competence-in-dividing, and Connect Compare Equate as the advanced technique was used as the data analysis method. The research finds that 53 color lexicons with plant attributes in 8 Madurese color lexicons, namely potѐ ‘white’, celleng ‘black’, mѐra ‘red’, bhiru ‘green’, konѐng ‘yellow’, cokklat ‘brown’, bhiru ‘blue’, and bungo ‘purple’. Furthermore, these plant attributes can be classified into fruits, flowers, vegetables, seeds, spices, leaves, trees, part of the tree, and part of the fruit. The domination of plant attributes in Madurese color lexicons emerges due to the sociocultural factors embodied in Madurese ethnic group itself, those are (1) farming is Madurese main way of living, (2) Madurese ethnic group respect the nature as the place where they can pray and thank God, and (3) some objects associated with color lexicons are abundantly available at their surroundings, thus they frequently use it in their daily life.