bluuebunny/crossref_metadata_2025_split huggingface dataset:
Group based video-conferencing for adults with depression: findings from a user-led qualitative data analysis using participatory theme elicitation
Authors: Best Paul , McConnell Tracey , Davidson Gavin , Badham Jennifer , Neill Ruth D. 
Published: December 2019

Abstract
Background
Accessing support services for depression has been historically difficult given the societal stigma that exists regarding the condition. Recent advances in digital technologies continue to be postulated as a potential panacea yet the results from research trials have been mixed with a range of effect sizes.

Methods
This article offers a different perspective by presenting a panel of end users (co-researchers) with qualitative interview data (n = 8) taken from a feasibility RCT of a group based video-conferencing service for depressed adults. The co-researcher panel were introduced to a new method of participatory data analysis known as Participatory Theme Elicitation (PTE). This method involves using network analysis techniques to create groupings and visual diagrams in order to support the generation of themes and minimise scientific researcher input/influence.

Results
Co-researchers reported that while VC based interventions appeared convenient, accessible and relatively low cost - additional training and support should be offered to improve uptake and retention. In addition, co-researchers suggested that further exploration is needed regarding the level of self-awareness one feels in a group based VC environment and whether this facilitates disclosure (through disinhibition) or increases anxiety.

Conclusion
The findings presented here appear to support existing (researcher and academic-led) literature in the field as well as suggest new areas for investigation. By presenting data generated solely by co-researchers, this article also adds to the evidence surrounding participatory analysis methods - particularly the growing need for robust approaches that are accessible and less time-consuming than those currently available.

Trial registration number
NCT03288506 (Clinicaltrials.gov) 20th Sept 2017 https://clinicaltrials.gov/ct2/show/NCT03288506
Toward implementing a fully automated truck guidance system at a seaport: identifying the roles, costs and benefits of logistics stakeholders
Authors: Carlan Valentin , Naudts Dries , Audenaert Pieter , Lannoo Bart , Vanelslander Thierry 
Published: December 2019

AbstractThe seaport-hinterland access infrastructures become more saturated leading to extra unpredictable costs for logistics operators. To keep their services competitive, infrastructure managers (such as port authorities) seek new approaches in managing and delivering information to their users. Starting from existing technological advancements and exploring the declared opportunities enabled by (near) future ones, a range of solutions (e.g. real-time information platforms, dynamic information boards or digital on-request notification solutions) can be pursued. This research investigates how an advanced truck guidance system (TGS) leverages on technology and leads to more efficient resource (infrastructure, equipment and labour) usage. The current paper merges two perspectives. The first conducts interviews with representatives of different logistics stakeholders to highlight their data needs. The second perspective is given by a review of information communication technology (ICT) innovative trends. These two perspectives provide an up-to-date overview of both needs (demand) and opportunities (supply) that challenge logistics stakeholders. This study proposes a TGS architecture that merges the two perspectives and identifies a stepwise approach to implement it. Therefore, the roles, costs and benefits brought to the logistics stakeholders are highlighted for each step. The key findings of this study show that road transport operators would benefit from operational savings and increased performance, while the other supply chain stakeholders can benefit from setting up a more reliable planning, better managing their infrastructure and developing added-value services for clients. To enable these benefits, the port administration could take the facilitator role and cover the TGS’s development costs.
Trichogenic effect of topical ketoconazole versus minoxidil 2% in female pattern hair loss: a clinical and trichoscopic evaluation
Authors: El-Garf Ahmed , Mohie Mohamed , Salah Eman 
Published: December 2019

Abstract
Background
Female pattern hair loss (FPHL) is a common non-scaring alopecia. Topical minoxidil is the only approved treatment for FPHL; however, it has frequent side effects. Ketoconazole is an antifungal with anti-androgenic properties.

Methods
The aim of this work was to evaluate the safety and possible trichogenic effects of ketoconazole in FPHL. Patients were randomly assigned into Group A with 20 patients who received 2% topical minoxidil solution and Group B involving 20 patients who were treated by 2% topical ketoconazole preparation. All patients were treated for 6 months and evaluated clinically plus via trichoscopy. Side effects were recorded, and patients’ satisfaction was measured.

Results
Regarding hair growth, a significant difference was detected between baseline and at 4th and 6th months in Group A. While in Group B, the improvement was delayed until the 6th month. Only 10% of Group B reported side effects. Patients’ satisfaction did not differ between the two groups.

Conclusions
Topical ketoconazole mediates a trichogenic effect in FPHL with few side effects. However, ketoconazole showed a delayed improvement versus minoxidil at similar concentrations. Further studies should evaluate the efficacy of higher concentrations of ketoconazole solutions for FPHL which is a promising therapy.

Trial registration
IRB approval status: reviewed and approved by IRB of Faculty of Medicine, Zagazig University; approval no. #3642
Prospective study to assess the tissue response to HPC-coated p48 flow diverter stents compared to uncoated devices in the rabbit carotid artery model
Authors: Lenz-Habijan Tim , Bhogal Pervinder , Bannewitz Catrin , Hannes Ralf , Monstadt Hermann , Simgen Andreas , Mühl-Benninghaus Ruben , Reith Wolfgang , Henkes Hans 
Published: December 2019

Abstract
Background
Flow diverters (FDs) are widely used in the treatment of intracranial aneurysms, but the required medication increases the risk of haemorrhagic complications and limits their use in the acute setting. Surface modified FDs may limit the need for dual antiplatelet therapy (DAPT). Hydrophilic polymer coating (HPC) may reduce the need of medication.

Methods
This explorative study, approved by the local authorities and the local welfare committee, compared stent behaviour and overall tissue response between HPC-coated FDs and uncoated FDs, both implanted into the common carotid arteries of eight New Zealand white rabbits. Endothelialisation, inflammatory response, and performance during implantation were assessed. Angiographic follow-up was performed to observe the patency of the devices after implantation and after 30 days. Histological examinations were performed at 30 days to assess foreign body reaction and endothelialisation. Kruskal-Wallis and Wilcoxon tests were used to compare non-parametric variables.

Results
Angiography showed that both coated and uncoated FDs performed well during implantation. All devices remained patent during immediate follow-up and after 30 days. Histopathology showed no significant difference in inflammation within the vessel wall between the two cohorts (2.12 ± 0.75 vs. 1.96 ± 0.79, p = 0.7072). Complete endothelialisation of the stent struts was seen with very similar (0.04 ± 0.02 mm vs. 0.04 ± 0.03 mm, p = 0.892) neoendothelial thickness between the two cohorts after 30 days.

Conclusion
Taking into account the limitation in sample size, non-significant differences between the HPC-coated and uncoated FDs regarding implantation, foreign body response, and endothelialisation were found.
Microbial biodiversity as related to crop succession and potato intercropping for management of brown rot disease
Authors: Messiha N. A. S. , Elhalag K. M. A. , Balabel N. M. , Farag S. M. A. , Matar H. A. , Hagag M. H. , Khairy A. M. , El-Aliem M. M. Abd , Eleiwa E. , Saleh O. M. E. , Farag N. S. 
Published: December 2019

AbstractPotato brown rot, caused by Ralstonia solanacearum, ranked globally as the second most important bacterial plant pathogen. In the present study, the influence of different cropping programs in potato brown rot management was investigated in four infected fields in Egypt. Two districts were selected as sandy soils in Giza (Wardan) and Behera (Ganuob El-Tahrir) governorates. The other two were selected as silty clay in Minufyia (Talia) and Beni-Suef (Sids) governorates. The followed crop succession included corn, potato intercropped with cabbage, onion, cowpea, wheat, corn again, and ended by potato. The pathogen was undetectable after corn, onion, and wheat. It decreased in cowpea and cabbage rhizospheres in the clay soils. The pathogen was undetectable at all districts, except at Sids, where the pathogen was significantly decreased but was not eradicated. This was possibly attributed to the high ratio of NO3− and Na+ at this district. Decreased R. solanacearum density after corn coincided with the high ratio of fluorescent pseudomonads, endospores, and actinomycetes, being most clear in the poor soils (Wardan) and less clear under iron excess at Ganoub El-Tahrir as well as the clay soils. Corn rhizosphere supported an array of antagonistic actinomycetes such as strains similar to Streptomyces intermedius, Streptomyces albidoflavus group, Streptomyces argenteolus group, and Streptomyces erythrogriseus. Intercropping potato with cabbage decreased the density of the pathogen in rhizosphere, which is associated with greater antagonistic fluorescent pseudomonads, Bacillus spp. and Serratia spp. Onion soil and rhizosphere associated with abundance of antagonists and fluorescent pseudomonads, followed by S. maltophilia and Bacillus spp. Wheat soil and rhizosphere supported fluorescent pseudomonads and antagonistic Streptomyces spp., especially in sandy soils. The pathogen was undetectable after planting the ending potato in the three districts, Wardan, Ganoub El-Tahrir, and Talia. This was accompanied by a general oligotrophism and increased ratio of fluorescent pseudomonads, endospores bacteria, and actinomycetes along with a diversity of R. solanacearum antagonists such as S. maltophilia, Citrobacter freundii, Acinetobacter sp., Delftia sp., and Serratia marcescens.
Effects of climatic changes on olive fly, Bactrocera oleae (Rossi) population dynamic with respect to the efficacy of its larval parasitoid in Egyptian olive trees
Authors: Abd El-Salam Ahmed Mohamed Ezzat , Salem Sadek Abdel-Wahed , Abdel-Rahman Ragab Shaker , El-Behery Hoda Hassan , Magd Elden Mona Ahmed 
Published: December 2019

Abstract
Background
The potential effects of two parameters of climatic change conditions (temperature and relative humidity) on the population dynamics of the olive fly across the two ecological areas in Egypt were studied. The olive trees in El-Behera Governorate are more affected by the olive fly compared to the olive trees in the orchard of El-Fayoum Governorate. In this study, the character of climate change in influencing the dynamics of insect population and associated parasites was discussed at the regional level.

Results
The results exhibited that the olive trees in the coast governorate were more susceptible to the olive fly than the inner governorate. The parasitism percentage was recorded 41.7 and 46.4% at the beginning of the seasons 2016 and 2017, respectively in El-Fayoum Governorate. In El-Behera Governorate, the maximum parasitism percentage was recorded 49.5% (2016 season), while the 2017 season, the parasitism percentage was recorded 50.4%. The majority of the ordinary parasite was Psyttalia concolor in the two regions.

Conclusion
The study clarifies that there is a positive correlation between B. oleae abundance and the effects of temperature and its parasitoid, Psyttalia concolor. Further, there is no significance found between the olive fly and relative humidity and its parasitoid populations.
Efficacy of soil solarization on black root rot disease and speculation on its leverage on nematodes and weeds of strawberry in Egypt
Authors: Abd-Elgawad Mahfouz M. M. , Elshahawy Ibrahim E. , Abd-El-Kareem Farid 
Published: December 2019

Abstract
Background
Strawberry (Fragaria ananassa Duch.) is an economically important crop in Egypt. Yet complex black root rot disease of strawberry caused by Fusarium solani, Rhizoctonia solani, and Pythium sp. can cause considerable yield losses. Therefore, this study aimed at evaluating different aspects of soil solarization against this disease. Such an evaluation would better be viewed in the context of other beneficial effects of soil solarization on nematodes and weeds.

Materials/methods
Growth agar disks, growth suspension, and resting stages of strawberry black root rot fungi were evaluated at different temperatures and exposure times using digital hot water bath. Cloth bags artificially infested with single fungal species were buried into the soil before soil solarization at soil depths of 1–10, 11–20, and 21–30 cm at three spots of each plot for each of the abovementioned fungi for 3, 6, or 9 weeks. The disease incidence and severity in solarized and un-solarized soil was compared with the application of the fungicide Actamyl. Effects of soil solarization on nematodes and weeds were also consulted.

Results
The lethal temperature to F. solani, Pythium sp., and R. solani was 58, 58, and 56 °C, respectively when exposure time was 1 min. Chlamydospores were killed at 62 °C while sclerotia were killed at 58 °C in hot water for 1 min. Maximum soil temperature in solarized soil was raised by 15, 14, and 12 °C at depths of 1–10, 11–20, and 21–30 cm as compared with non-solarized soil. Solarization for 3, 6, and 9 weeks significantly reduced the disease incidence and severity and increased the strawberry yield. Complete reduction in total count of all tested fungi was obtained after 9 weeks at all tested depths. A review of collective soil pest and pathogen control via solarization documented its beneficial application.

Conclusion
The study may exploit hot months in Egypt for soil solarization against the serious root rot disease either singly or in an integrated pest management program.
Ecological and microbiological diversity of chigger mites, including vectors of scrub typhus, on small mammals across stratified habitats in Thailand
Authors: Chaisiri Kittipong , Gill A. Christina , Stekolnikov Alexandr A. , Hinjoy Soawapak , McGarry John W. , Darby Alistair C. , Morand Serge , Makepeace Benjamin L. 
Published: December 2019

Abstract
Background
Scrub typhus, caused by a bacterial pathogen (Orientia spp.), is a potentially life-threatening febrile illness widely distributed in the Asia-Pacific region and is emerging elsewhere. The infection is transmitted by the larval stage of trombiculid mites (“chiggers”) that often exhibit low host specificity. Here, we present an analysis of chigger ecology for 38 species sampled from 11 provinces of Thailand and microbiomes for eight widespread species.

Results
In total, > 16,000 individual chiggers were collected from 1574 small mammal specimens belonging to 18 species across four horizontally-stratified habitat types. Chigger species richness was positively associated with higher latitudes, dry seasonal conditions, and host maturity; but negatively associated with increased human land use. Human scrub typhus incidence was found to be positively correlated with chigger species richness. The bacterial microbiome of chiggers was highly diverse, with Sphingobium, Mycobacterium, Neisseriaceae and various Bacillales representing the most abundant taxa. Only Leptotrombidium deliense was found to be infected with Orientia and another potential pathogen, Borrelia spp., was frequently detected in pools of this species. β-diversity, but not α-diversity, was significantly different between chigger species and geographic regions, although not between habitat types.

Conclusion
Our study identified several key environmental and host-derived correlates of chigger species richness across Thailand, which in turn impacted on human scrub typhus incidence. Moreover, this first extensive field survey of the chigger microbiome revealed species- and province-level variation in microbial β-diversity across the country, providing a framework for future studies on interactions between pathogens and other symbionts in these understudied vectors.
Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial
Authors: Kluin-Nelemans Hanneke C. , Hoster Eva , Hermine Olivier , Walewski Jan , Geisler Christian H. , Trneny Marek , Stilgenbauer Stephan , Kaiser Florian , Doorduijn Jeanette K. , Salles Gilles , Szymczyk Michal , Tilly Hervé , Kanz Lothar , Schmidt Christian , Feugier Pierre , Thieblemont Catherine , Zijlstra Josée M. , Ribrag Vincent , Klapper Wolfram , Pott Christiane , Unterhalt Michael , Dreyling Martin H. 
Published: December 2019

PURPOSE In an update of the randomized, open-label, phase III European Mantle Cell Lymphoma (MCL) Elderly trial (ClinicalTrials.gov identifier: NCT00209209 ), published in 2012, we aimed to confirm results on long-term outcome focusing on efficacy and safety of long-term use of rituximab maintenance. PATIENTS AND METHODS Five hundred sixty patients with newly diagnosed MCL underwent a first random assignment between rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) and rituximab, fludarabine, and cyclophosphamide (R-FC) induction, followed by a second random assignment in 316 responders between rituximab and interferon alfa maintenance, to be continued until progression. We compared progression-free survival from the second randomization and overall survival (OS) from the first or second randomizations. RESULTS After a median follow-up time of 7.6 years, the previously described difference in OS between the induction arms persisted (median, 6.4 years after R-CHOP [n = 280] v 3.9 years after R-FC [n = 280]; P = .0054). Patients responding to R-CHOP had median progression-free survival and OS times of 5.4 and 9.8 years, respectively, when randomly assigned to rituximab (n = 87), compared with 1.9 years ( P < .001) and 7.1 years ( P = .0026), respectively, when randomly assigned to interferon alfa (n = 97). In 58% and 32% of patients treated with R-CHOP, rituximab maintenance was still ongoing 2 and 5 years from start of maintenance, respectively. After R-FC, rituximab maintenance was associated with an unexpectedly high cumulative incidence of death in remission (22% at 5 years). Toxicity of rituximab maintenance was low after R-CHOP (grade 3-4 leukopenia or infection < 5%) but more prominent in patients on rituximab maintenance after R-FC, in whom grade 3-4 leukopenia (up to 40%) and infections were frequent (up to 15%). CONCLUSION The excellent results of R-CHOP followed by rituximab maintenance until progression for older patients with MCL persisted in a mature follow-up. Prolongation of rituximab maintenance beyond 2 years is effective and safe.
Predicting Weight Loss Using Psychological and Behavioral Factors: The POUNDS LOST Trial
Authors: Liu Xiaoran , Hanseman Dennis J , Champagne Catherine M , Bray George A , Qi Lu , Williamson Donald A , Anton Stephen D , Sacks Frank M , Tong Jenny 
Published: December 2019

Abstract

Context
Eating habits and food craving are strongly correlated with weight status. It is currently not well understood how psychological and behavioral factors influence both weight loss and weight regain.

Objective
To examine the associations between psychological and behavioral predictors with weight changes and energy intake in a randomized controlled trial on weight loss.

Design and setting
The Prevention of Obesity Using Novel Dietary Strategies is a dietary intervention trial that examined the efficacy of 4 diets on weight loss over 2 years. Participants were 811 overweight (body mass index, 25-40.9 kg/m2; age, 30-70 years) otherwise healthy adults.

Results
Every 1-point increase in craving score for high-fat foods at baseline was associated with greater weight loss (-1.62 kg, P = .0004) and a decrease in energy intake (r = -0.10, P = .01) and fat intake (r = -0.16, P &lt; .0001) during the weight loss period. In contrast, craving for carbohydrates/starches was associated with both less weight loss (P &lt; .0001) and more weight regain (P = .04). Greater cognitive restraint of eating at baseline was associated with both less weight loss (0.23 kg, P &lt; .0001) and more weight regain (0.14 kg, P = .0027), whereas greater disinhibition of eating was only associated with more weight regain (0.12 kg, P = .01).

Conclusions
Craving for high-fat foods is predictive of greater weight loss, whereas craving for carbohydrates is predictive of less weight loss. Cognitive restraint is predictive of less weight loss and more weight regain. Interventions targeting different psychological and behavioral factors can lead to greater success in weight loss.
Nonlinear optical absorption properties of zirconium selenide in generating dark soliton and dark-bright soliton pairs
Authors: Zheng Yue , Wang Mengxiao , Zhao Rui , Zhang Huanian , Liu Danhua , Li Dengwang 
Published: December 2019

Our work reports the preparation of zirconium selenide (

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)-polyvinyl alcohol (PVA) film-type saturable absorber (SA) and its nonlinear absorption performance in obtaining dark soliton and dark-bright soliton pairs in an Er-doped fiber (EDF) laser for the first time, to the best of our knowledge. The saturation intensity and modulation depth of the

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SA were

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and 2.3%, respectively. Due to the modulation of the SA, under a pump power of 525.2 mW, stable dark soliton operation with an average output power of 9.75 mW, and a pulse repetition frequency of 20.84 MHz, a pulse width of 3.85 ns was attained successfully. By adjusting the state of the polarization controllers, dark-bright soliton pairs were also observed. To the best of our knowledge, this was the first demonstration focusing on the nonlinear optical absorption applications of

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in obtaining dark soliton and dark-bright soliton pairs. Our results show that

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is a good two-dimensional SA material for acting as an ultrafast optical device due to its suitable nonlinear optical absorption properties.
All optically driven memory device for terahertz waves
Authors: Chen Si-Chao , Yuan Hong-Kuan , Zhai Zhao-Hui , Du Liang-Hui , Zhong Sen-Cheng , Zhu Hong-Fu , Shi Qi-Wu , Huang Wan-Xia , Li Ze-Ren , Zhu Li-Guo 
Published: December 2019

We demonstrate an all optically driven memory device based on vanadium dioxide (

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) for terahertz (THz) waves. By easily tuning the power of illuminating light, a

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memory device is coded in reconfigurable and multi-level states, taking advantage of its hysteretic metal-to-insulator phase transition (MIT). Further, writing with intense femtosecond pulses, the memory effects are performed by non-thermal photo-induced MIT, and resultant 2-bit coding with a write time of 22 µs is demonstrated, yielding a dramatically improved write rate compared to existing thermally controlled

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memory device. The proposed all optically driven

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-based memory device paves the way for actively manipulating THz waves within robust reconfigurable high-speed memory functionality.