bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combining sources of information to increase survey response rates
Authors: Guinalíu Miguel , Díaz de Rada Vidal 
Published: December 2020

Purpose
The purpose of this paper is to show that mixed methods applied sequentially provide sufficient knowledge of topics under study.

Design/methodology/approach
This paper conducted an analysis of a real case using descriptive statistical and regression techniques.

Findings
The present study proposes the use of the so-called “sequential mixed-modes” in survey-based market research. This technique is based on the successive application of different information collection techniques (face-to-face, telephone and internet-based surveys); it offers four fundamental advantages: increased coverage rate; higher response rate; lower costs; and greater cooperation.

Research limitations/implications
In addition to the normal limitations associated with conclusions derived from case studies, the data collection was carried out in only one autonomous community (Spain) and focussed only on one theme.

Practical implications
Firstly, it was found that data collection through mixed sequential modes substantially increases response rates in online surveys. This is particularly important as, in recent years, data collection through the internet has become almost standard market research practice. Secondly, the sample that resulted from the joint use of the three data collection modes more accurately reflected the distinctive features of the universe under study. A third recommendation is that the use of internet-based self-administered surveys is especially promising with individuals with a higher level of education and among students.

Originality/value
The decrease in the response rate is one of the greatest challenges of survey-based market research, given its impact on sample representativeness. This paper addresses this problem and exposes the advantages of the sequential use of mixed modes in the collection of information.
Inter-organizational learning within an organization? Mainstreaming gender policies in the Swedish ministry of foreign affairs
Authors: Solheim Marte C.W. , Moss Sigrun Marie 
Published: December 2020

PurposeThe purpose of this paper is to explain how theories of inter-organizational learning can create new insights and nuances to how processes of intra-organizational learning come about in a single, complex and multi-sited organization.Design/methodology/approachA constructivist thematic analysis of the “Handbook of Feminist Foreign Policy” produced by the Swedish Ministry of Foreign Affairs (SMFA) is completed, exploring the organization’s own presentation of the complex learning processes that took place when implementing the new policy in 2014.FindingsThe literature on inter-organizational learning has a so far unexplored explanatory potential to understand learning processes that take place in complex, multi-sited organizations. This case demonstrates why and how this potential is relevant to exploit. Five themes are constructed from the analysis; four pointing out how gender mainstreaming is spread throughout the different parts of the organization and one detailing how the learning process has provided the SMFA knowledge exportable to other organizations.Originality/valueDue to the complexity in large, multi-sited organizations today, this paper argues what is classically understood as solely inter-organizational processes could also apply to a single organization, as the learning processes this engages in, transitions intra- and inter-organizational learning. The study advances current understandings through exploring mechanisms of gender mainstreaming.
Tourist gaze and beyond: state of the art
Authors: Samarathunga W.H.M.S. , Cheng Li 
Published: December 2020

Purpose
The tourist gaze remains a key concept in tourism research. The purpose of this paper is to comprehend the theoretical and empirical development of the tourist gaze notion and its contributions to tourism knowledge, identifying potential research directions by reviewing and analyzing articles that have defined, refined and applied the concept of the tourist gaze.

Design/methodology/approach
The study identified 109 relevant research papers primarily through the Web of Science and Scopus databases. Google Scholar, ResearchGate.net and Academia.edu were used to capturing additional work not indexed in the key databases. Qualitative content analysis was used to map the evolution of the concept, distinguish between different perspectives and identify gaps in the tourist gaze literature.

Findings
This “state of the art” paper on tourist gaze outlines Foucault’s original work on gaze and power, which underpins subsequent theorization within tourism. The study identifies how the tourist gaze operates in different contexts and circumstances allowing the development of gaze theory. Importantly, the evolution of the gaze theory is presented after analyzing the knowledge gaps, the contexts in which it was used, the methodologies with which it was applied. Based on the findings, the study proposes future works of gaze with the use of technology, science, nature and social media.

Originality/value
This paper is among one of the first states of the art papers in tourism literature that comprehensively analyzes the works on the tourist gaze, tracing its evolution and identifying future research directions to address gaps in existing knowledge.
What is the anatomical basis of labiaplasty? A review of normative datasets for female genital anatomy
Authors: Hayes Jennifer A. , Temple‐Smith Meredith J. 
Published: December 2020

BackgroundDespite increasing numbers of labiaplasties being performed, there is little quantitative information on normal labial diversity to guide medical education, patient education and surgical treatment.AimThis scoping review will determine what is known in the published literature about the anatomical basis of normal for labia and female genital cosmetic surgery (FCGS).Materials and methodsThe scoping review identified ten population‐based studies that recorded labial dimensions by searching three electronic databases utilising a Preferred Reporting Items for Systematic Reviews and Meta‐Analyses search strategy. Strict inclusion and exclusion criteria were applied and then reference lists were scrutinised until no further articles that met the criteria were located.ResultsThese studies showed significant variation in labial length (range 5–100 mm) and width (range 1–60 mm). Labia minora were wider in pre‐menopausal women than in post‐menopausal women, protruding labia minora were more common than not, and asymmetry between right and left labia was common. Variation in recruitment, inclusion and exclusion criteria, and measurement did not allow for summation of the data sets.ConclusionThis information could usefully be added to medical textbooks and teaching to ensure that medical graduates are sufficiently informed about normal variation in female genital anatomy to assess and advise women seeking FGCS.
Depression, anxiety, perceived stress, and their changes predicted medical adherence over 9 months among patients with coronary heart disease
Authors: Fan Yunge , Shen Biing‐Jiun , Tay Hung Yong 
Published: December 2020

ObjectivesAlthough effective medical treatments have proved to successfully improve prognoses and outcomes of patients with coronary heart disease (CHD), low adherence to treatments is still common among patients. Deleterious impact of psychological distress on medical adherence has been recognized; however, few studies examined the influence of change in psychological distress on attenuation in adherence. This study investigated whether three common manifestations of distress (depression, anxiety, and perceived stress) and their changes predicted decline in medical adherence among CHD patient over 9 months.DesignA three‐wave longitudinal study.MethodsParticipants were 255 CHD patients with a mean age of 63 years. Psychological distress, medication adherence, and specific treatment adherence were assessed at baseline, 3 months, and 9 months. Hierarchical regression analyses were conducted to examine the influences of psychological distress on medical adherence over 9 months. All models were adjusted for baseline medication or specific adherence, demographic, and medical covariates.ResultsBaseline depression and its changes over time significantly predicted greater decline in both medication adherence (βs = .15–.20, ps < .05) and specific adherence (βs = −.21 to −.15, ps < .05). Anxiety showed a similar trend. For perceived stress, baseline and its change significantly predicted specific adherence over 9 months (βs = −.30 to −.23, ps < .01), but did not predict medication adherence at 3 and 9 months.ConclusionsFindings underline the necessity of tracking various forms of psychological distress over time for CHD patients to promote medical adherence and further improve the disease prognosis.
Growth, development, and phenotypic spectrum of individuals with deletions of 2q33.1 involving SATB2
Authors: Zarate Yuri A. , Bosanko Katherine A. , Thomas Mary Ann , Miller David T. , Cusmano‐Ozog Kristina , Martinez‐Monseny Antonio , Curry Cynthia J. , Graham John M. , Velsher Lea , Bekheirnia Mir Reza , Seidel Veronica , Dedousis Demitrios , Mitchell Anna L. , DiMarino Amy M. , Riess Angelika , Balasubramanian Meena , Fish Jennifer L. , Caffrey Aisling R. , Fleischer Nicole , Pierson Tyler Mark , Lacro Ronald V. 
Published: December 2020

AbstractSATB2‐Associated syndrome (SAS) is an autosomal dominant, multisystemic, neurodevelopmental disorder due to alterations in SATB2 at 2q33.1. A limited number of individuals with 2q33.1 contiguous deletions encompassing SATB2 (ΔSAS) have been described in the literature. We describe 17 additional individuals with ΔSAS, review the phenotype of 33 previously published individuals with 2q33.1 deletions (n = 50, mean age = 8.5 ± 7.8 years), and provide a comprehensive comparison to individuals with other molecular mechanisms that result in SAS (non‐ΔSAS). Individuals in the ΔSAS group were often underweight for age (20/41 = 49%) with a progressive decline in weight (95% CI = −2.3 to −1.1, p < 0.0001) and height (95% CI = −2.3 to −1.0, p < 0.0001) Z‐score means from birth to last available measurement. ΔSAS individuals were often noted to have a broad spectrum of facial dysmorphism. A composite image of ΔSAS individuals generated by automated image analysis was distinct as compared to matched controls and non‐ΔSAS individuals. We also present additional genotype–phenotype correlations for individuals in the ΔSAS group such as an increased risk for aortic root/ascending aorta dilation and primary pulmonary hypertension for those individuals with contiguous gene deletions that include COL3A1/COL5A2 and BMPR2, respectively. Based on these findings, we provide additional care recommendations for individuals with ΔSAS variants.
Hypomethylation of NLRP3 gene promoter discriminates glucocorticoid‐resistant from glucocorticoid‐sensitive idiopathic nephrotic syndrome patients
Authors: Lucafò Marianna , Granata Simona , Bonten Erik J. , McCorkle Robert , Stocco Gabriele , Caletti Chiara , Selvestrel Davide , Cozzarolo Alessio , Zou Chan , Cuzzoni Eva , Pasini Andrea , Montini Giovanni , Gambaro Giovanni , Decorti Giuliana , Evans William , Zaza Gianluigi 
Published: December 2020

AbstractTo assess whether NLRP3 gene promoter methylation was able to discriminate glucocorticoid (GC)‐resistant from GC‐sensitive idiopathic nephrotic syndrome (INS), patients with minimal change disease (MCD) or focal segmental glomerulosclerosis (FSGS), we measured the methylation level of NLRP3 promoter in DNA from peripheral blood cells of 10 adult patients with GC‐resistant FSGS already in hemodialysis and 18 patients with GC‐sensitive INS (13 MCD/5 FSGS) and in 21 pediatric patients with INS with MCD/FSGS before starting any treatment. Association of NLRP3 inflammasome with GC resistance was recapitulated in vitro in monocytic cell lines (THP‐1 and U937). In both adults and pediatric patients, NLRP3 promoter methylation was significantly reduced in GC‐resistant compared with GC‐sensitive patients. Indeed, NLRP3 methylation distinguished GC‐resistant and GC‐sensitive patients (area under the receiver operating characteristic curve [AUROC] 86.7% in adults, p = 0.00019, and 73.5% in children, p = 0.00097). NLRP3 knock‐down augmented sensitivity to GCs in THP‐1 cells, whereas NLRP3 inflammasome activation lowered GC receptor concentration, increasing GC resistance in U937 cells. Our results uncovered a new biological mechanism by which patients with INS may acquire GC resistance, that could be used in future as a novel noninvasive diagnostic tool.
Study Highlights

WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC?

☑ Approximately 80% of patients with idiopathic nephrotic syndrome (INS) respond to glucocorticoids, with the remaining 20% being steroid‐resistant.

WHAT QUESTION DID THIS STUDY ADDRESS?
☑ Whether NLRP3 gene promoter methylation was able to discriminate glucocorticoid‐resistant from glucocorticoid (GC)‐sensitive INS.

WHAT DOES THIS STUDY ADD TO OUR KNOWLEDGE?
☑ In both adults and children, NLRP3 promoter methylation was significantly reduced in leukocytes of patients with GC‐resistant compared with GC‐sensitive INS. NLRP3 inflammasome activation lowered GC receptor concentration and augmented GC resistance, whereas NLRP3 knockdown increased sensitivity to GCs in cell lines representative of monocytes (U937 and THP1).

HOW MIGHT THIS CHANGE CLINICAL PHARMACOLOGY OR TRANSLATIONAL SCIENCE?
☑ Our findings uncovered a new biological mechanism whereby patients with INS may develop resistance to GCs that could be used in the future as a novel noninvasive diagnostic tool.
Irradiation of the head reduces adult hippocampal neurogenesis and impairs spatial memory, but leaves overall health intact in rats
Authors: Lensu Sanna , Waselius Tomi , Mäkinen Elina , Kettunen Heikki , Virtanen Ari , Tiirola Marja , Penttonen Markku , Pekkala Satu , Nokia Miriam S. 
Published: December 2020

AbstractTreatment of brain cancer, glioma, can cause cognitive impairment as a side‐effect, possibly because it disrupts the integrity of the hippocampus, a structure vital for normal memory. Radiotherapy is commonly used to treat glioma, but the effects of irradiation on the brain are still poorly understood, and other biological effects have not been extensively studied. Here, we exposed healthy adult male rats to moderate‐dose irradiation of the head. We found no effect of irradiation on systemic inflammation, weight gain or gut microbiota diversity, although it increased the abundance of Bacteroidaceae family, namely Bacteroides genus in the gut microbiota. Irradiation had no effect on long‐term potentiation in the CA3‐CA1 synapse or endogenous hippocampal electrophysiology, but it did reduce adult hippocampal neurogenesis and impaired short‐term spatial recognition memory. However, no overall cognitive impairment was observed. To summarize, our results suggest that in adult male rats head irradiation does not compromise health or cognition overall even though the number of new, adult‐born hippocampal neurons is decreased. Thus, the sole effects of head irradiation on the body, brain and cognition might be less harmful than previously thought, and the cognitive decline experienced by cancer patients might originate from physiological and mental effects of the disease itself. Therefore, to increase the translational value of animal studies, the effects of irradiation should be studied together with cancer, in older animals, using varying irradiation protocols and doses.
Search for top‐down and bottom‐up drivers of latitudinal trends in insect herbivory in oak trees in Europe
Authors: Valdés‐Correcher Elena , Moreira Xoaquín , Augusto Laurent , Barbaro Luc , Bouget Christophe , Bouriaud Olivier , Branco Manuela , Centenaro Giada , Csóka György , Damestoy Thomas , Dobrosavljević Jovan , Duduman Mihai‐Leonard , Dulaurent Anne‐Maïmiti , Eötvös Csaba B. , Faticov Maria , Ferrante Marco , Fürjes‐Mikó Ágnes , Galmán Andrea , Gossner Martin M. , Hampe Arndt , Harvey Deborah , Gordon Howe Andrew , Kadiri Yasmine , Kaennel‐Dobbertin Michèle , Koricheva Julia , Kozel Alexander , Kozlov Mikhail V. , Lövei Gábor L. , Lupaștean Daniela , Milanović Slobodan , Mrazova Anna , Opgennoorth Lars , Pitkänen Juha‐Matti , Popova Anna , Popović Marija , Prinzing Andreas , Queloz Valentin , Roslin Tomas , Sallé Aurélien , Sam Katerina , Scherer‐Lorenzen Michael , Schuldt Andreas , Selikhovkin Andrey , Suominen Lassi , Tack Ayco J. M. , Tahadlova Marketa , Thomas Rebecca , Castagneyrol Bastien 
Published: December 2020

AbstractAimThe strength of species interactions is traditionally expected to increase toward the Equator. However, recent studies have reported opposite or inconsistent latitudinal trends in the bottom‐up (plant quality) and top‐down (natural enemies) forces driving herbivory. In addition, these forces have rarely been studied together thus limiting previous attempts to understand the effect of large‐scale climatic gradients on herbivory.LocationEurope.Time period2018–2019.Major taxa studiedQuercus robur.MethodsWe simultaneously tested for latitudinal variation in plant–herbivore–natural enemy interactions. We further investigated the underlying climatic factors associated with variation in herbivory, leaf chemistry and attack rates in Quercus robur across its complete latitudinal range in Europe. We quantified insect leaf damage and the incidence of specialist herbivores as well as leaf chemistry and bird attack rates on dummy caterpillars on 261 oak trees.ResultsClimatic factors rather than latitude per se were the best predictors of the large‐scale (geographical) variation in the incidence of gall‐inducers and leaf‐miners as well as in leaf nutritional content. However, leaf damage, plant chemical defences (leaf phenolics) and bird attack rates were not influenced by climatic factors or latitude. The incidence of leaf‐miners increased with increasing concentrations of hydrolysable tannins, whereas the incidence of gall‐inducers increased with increasing leaf soluble sugar concentration and decreased with increasing leaf C : N ratios and lignins. However, leaf traits and bird attack rates did not vary with leaf damage.Main conclusionsThese findings help to refine our understanding of the bottom‐up and top‐down mechanisms driving geographical variation in plant–herbivore interactions, and indicate the need for further examination of the drivers of herbivory on trees.
Chemical conversion of aged hepatocytes into bipotent liver progenitor cells
Authors: Huang Yu , Miyamoto Daisuke , Li Pei‐Lin , Sakai Yusuke , Hara Takanobu , Adachi Tomohiko , Soyama Akihiko , Hidaka Masaaki , Kanetaka Kengo , Gu Wei‐Li , Eguchi Susumu 
Published: December 2020

AbstractAimIn the aging society, understanding the influence of hepatocyte age on hepatocyte donation may inform efforts to expand alternative cell sources to mitigate liver donor shortage. A combination of the molecules Y27632, A‐83‐01, and CHIR99021 has been used to reprogram rodent young hepatocytes into chemically induced liver progenitor (CLiP) cells; however, whether it could also reprogram aged hepatocytes has not yet been elucidated.MethodsPrimary hepatocytes were isolated from aged and young donor rats, respectively. Hepatic histological changes were evaluated. Differences in gene expression in hepatocytes were identified. The in vitro reprogramming plasticity of hepatocytes as evidenced by CLiP conversion and the hepatocyte and cholangiocyte maturation capacity of reprogrammed CLIPs were analyzed. The effect of hepatocyte growth factor (HGF) on cell propagation was also investigated.ResultsThe histological findings revealed ongoing liver damage with inflammation, fibrosis, senescence, and ductular reaction in aged livers. Microarray analysis showed altered gene expression profiles in hepatocytes from aged donors, especially with regard to metabolic pathways. Aged hepatocytes could be converted into CLiPs (Aged‐CLiPs) expressing progenitor cell markers, but with a relatively low proliferative rate compared with young hepatocytes. Aged‐CLiPs possessed both hepatocyte and cholangiocyte maturation capacity. HGF facilitated CLiP conversion in aged hepatocytes, which was partly related to the activation of Erk1 and Akt1 signaling.ConclusionsAged rat hepatocytes have retained reprogramming plasticity as evidenced by CLiP conversion in culture. HGF promoted proliferation and CLiP conversion in aged hepatocytes. Hepatocytes from aged donors may be used as an alternative cell source to mitigate donor shortage.
Understanding the adoption and willingness to pay for internet of things services
Authors: Kasilingam Dharun , Krishna Rajneesh 
Published: December 2020

AbstractInternet of Things (IOT) involves devices that can interact with one another by connecting to the internet and sending information, ultimately improving human lives. This research is one of the first in literature that seeks to understand the variables that influence consumer adoption of IOT products offered as services against a monthly premium. The influence of value dimensions on IOT on its adoption and consumer willingness to pay a premium was studied. A sample consisting of 1623 responses collected through an online survey was analysed using partial least squares structural equation modelling. The moderating role of age groups, gender and income levels was also analysed. Out of sample prediction and overfitting of the model were used to assess predictive validity both for the full data set and across groups using PLS Predict. Perceived playfulness, personal innovativeness and convenience value were the most significant variables affecting attitude and intention to use IOT services. Attitude mediated most relationships in the model. Moderation analysis using demographic variables of gender, age groups and income levels revealed significant differences in the strengths of the relationships in the model. Predictive validity assessment with PLS showed revealed high predictive power of the model for adoption outside the selected sample. The results can help marketers segment and design business strategies to expedite the diffusion and adoption of the technology in the market. The need for a shift in the B2C IOT market from product‐centric to a product‐as‐a‐service business to maximize value to consumers is thus proposed.
Antecedents and consequences of panic buying: The case of COVID‐19
Authors: Prentice Catherine , Quach Sara , Thaichon Park 
Published: December 2020

AbstractPanic buying emerged as a significant phenomenon during the COVID‐19 pandemic. This study draws on the scarcity principle, crowd psychology and contagion theory to investigate the antecedents and consequences of panic buying. The antecedents included in this study are government measures, media and peer influence and the fear of missing out. The consequences are founded on a sense of security and guilt. Retailer intervention is included as a moderator to the proposed main effects. Data were collected from 341 consumers who engaged in panic buying and were residents of the United States and Australia during the COVID‐19 pandemic. Structural equation modelling was employed to test the proposed model. The results show that the proposed antecedents (except fear of missing out) were significantly related to panic buying, which in turn had a significant influence on panic buyers' psychological outcomes. The moderating effects of retailer intervention varied across different product categories. Discussion and implications of these findings are provided for policy makers, customers and practitioners.