bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diversification of health-promoting phytochemicals in radish (Raphanus raphanistrum) and kale (Brassica oleracea) micro-greens using high light bio-fortification
Authors: Loedolff Bianke 
Published: February 2020

Background: Fruits and vegetables contain significant amounts of biologically active phytochemicals (such as polyphenols, glucosinolates, phytoestrogens, and carotenoids, amongst others), which have associated with human health and nutrition. Numerous bio-fortification strategies are employed to enhance the nutritional profile of plant-based foods to address and minimize the severe outcomes of malnutrition.Methods: Using an established high light-induced bio-fortification strategy, we aimed to augment the accumulation of health-promoting phytochemicals in a selection of Brassica micro-greens (kale and radish). High throughput tandem mass spectrometry was used to identify the differential accumulation of phytochemicals and subsequently determined their antioxidant capacity. Using a classical DNA protection assay, we demonstrated that human genomic DNA could be protected from oxidative stress.Results: We report here on the potential link between the increased phytochemicals, total antioxidant, capacity and potential consequent role in human DNA protection.Conclusion: Bio-fortification implemented as a future strategy could enhance the phytochemical profile and consequent antioxidant potential for the development of functional foods and food supplements.Keywords: antioxidant, bio-fortification, Brassica, DNA protection, high light, micro-greens, phytochemicals
Does 5-alpha Reductase Inhibitor Use Improve The Efficacy of Intravesical Bacille Calmette-Guérin (BCG) for Non-muscle Invasive Bladder Cancer?
Authors: Al-Hogbani Mofarej , Gilbert Sophie , Lodde Michele , Fradet Yves , Toren Paul 
Published: February 2020

BACKGROUND: Prior research implicates the androgen receptor pathway as important in bladder cancer progression and recurrence. In particular, use of 5-alpha reductase inhibitors (5-ARIs) appears to improve bladder cancer outcomes. This study aims to determine if concomitant use of 5-ARIs with intravesical Bacille Calmette-Guérin (BCG) decreases recurrences in patients with non-muscle invasive bladder cancer (NMIBC). MATERIALS & METHODS: This retrospective analysis included male patients diagnosed with NMIBC who were treated with induction intravesical BCG at our institution from 2013 to 2018. Patients were excluded who received prior induction BCG. Recurrence and progression-free survival were estimated using the Kaplan-Meier method. Univariate and multivariate analyses were performed using Cox proportional hazards and Poisson events models. RESULTS: We identified 206 male patients, of whom 39 received 5-ARIs and 167 did not. Most patients (72.8%) received >6 instillations of BCG, with 20.4% completing all induction and maintenance treatments during a median follow up of 3.31 years. There were no significant differences in recurrence or progression-free survival between 5-ARI users or non-users (59% vs 55.7%; p = 0.72 and 97.4% vs 98.2%; p = 1.00, respectively). Similarly, no differences in the number of recurrences between groups was observed ( p = 0.78). However, the proportion of patients who completed all prescribed BCG installations was higher among 5-ARI users (39.7% vs 17.9 %, p = 0.07). CONCLUSIONS: In contrast to prior reports, our study does not suggest that 5-ARI use decreases the recurrence rate in men receiving induction BCG for NMIBC. However, our results suggest 5-ARI use may improve patient tolerance to BCG.
Web based Expert System dalam Penanganan Kesehatan dan Penyakit Kucing di Kota Padang
Authors: Vadreas Andrew Kurniawan , Nirad Dwi Welly Sukma , Wenti Husni 
Published: February 2020

Paper ini membahas tentang penanganan penyakit pada kucing dengan dukungan expert system. Dengan mengimplementasikan perkembangan teknologi saat ini yang dapat menyelesaikan suatu permasalahan layaknya seorang manusia. Penanganan penyakit pada kucing saat ini masih dilakukan dengan uji laboratorium, dan menggunakan kertas sebagai form perhitungan hasil diagnosa yang dilakukan oleh dokter pada Dinas Peternakan dan Kesehatan Hewan dan Klinik Zech Small Animal di kota Padang. Dari permasalahan tersebut dibuatlah suatu web tempat untuk konsultasi berbagai cara penanganan kesehatan kucing baik berupa mencegah dan mengobati penyakit kucing dari gejala-gejala yang ditimbulkan. Tahapan penelitian dimulai dari pengumpulan data berupa interview langsung dengan dokter hewan dan beberapa buku sebagai study literatur, dilanjutkan dengan perancangan sistem aplikasi berbasis web menggunakan metode forward chaining, kemudian dilakukan pengembangan serta pengujian sistem pada Dinas Peternakan dan Kesehatan Hewan dan Klinik Zech Animal di kota Padang. Terdapat 21 Penyakit yang dihasilkan diimplementasikan kedalam sebuah aplikasi web based expert system. Aplikasi ini mampu membantu para pecinta kucing (cat lovers) untuk melakukan penanganan penyakit dan pencegahan pada kucing kesayangan mereka.
PERBEDAAN METODE PRICING, KEBERAGAMAN PRODUK TERHADAP KEPUASAN KONSUMEN PASAR TRADISIONAL
Authors: Arif Donny , Yucha Nikma , Ekasari Ratna , Purnamasari Wulan 
Published: February 2020

Pasar tradisional merupakan salah satu titik kumpul perekonomian masyarakat. Sedangkan pasar tradisional identik dengan kumuh, bau, kotor dan sebagainya. Perlunya strategi pengembangan pasar tradisional agar pasar tradisional tetap menjadi pilihan pembeli untuk berbelanja kebutuhan sehari-hari. Pengembangan pasar memang tidaklah mudah, revitalisasi pasar memakan biaya yang tinggi. Pasar yang ingin berkembang dengan bantuan pemerintah melalui kebijakan revitalisasi pasar hendaknya tidak hanya menghasilkan kemajuan yang tampaknya nyaman secara fisik. Jenis penelitian dalam penulisan penelitian ini adalah penelitian lapangan (field research), yaitu penelitian yang dilakukan dilokasi penelitian dengan melakukan pengamatan tentang suatu fenomena dalam keadaan ilmiah. Sedangkan dalam pengumpulan data dalam penelitian menggunakan metode pengumpulan dengan observasi, wawancara dan kuesioner.
Penelitian ini menggunakan metode analisis kuantitatif. Lokasi penelitian dilaksanakan di Pasar Krisna Madubronto Kabupaten Sidoarjo. Hasil penelitian ini bertujuan mengetahui dan menganalisis pengaruh persepsi harga, keberagaman produk, dan lokasi terhadap kepuasan konsumen di Pasar digital
PENCAPAIAN KINERJA PERUSAHAAN KELUARGA MELALUI TINGKAT KESIAPAN SUKSESOR DAN HUBUNGAN ANTAR ANGGOTA KELUARGA DAN BISNIS
Authors: Soeparto Wahyudi Henky 
Published: February 2020

Perusahaan keluarga merupakan salah satu penyumbang produk domestik bruto (PDB) terbesar di Indonesia. Universitas Ciputra memfasilitasi mahasiswa calon penerus perusahaan keluarga dengan membuat guild family business. Rencana suksesi dan komunikasi merupakan hal yang penting bagi perusahaan keluarga. Perusahaan keluarga harus mendidik suksesor yang potensial agar rencana suksesi dapat berlajan dengan baik. Tujuan penelitian ini adalah untuk menguji pengaruh tingkat kesiapan suksesor terhadap kinerja perusahaan keluarga; menguji pengaruh hubungan antar anggota keluarga dan bisnis terhadap kinerja perusahaan keluarga.
Penelitian ini menggunakan pendekatan kuantitatif. Populasi dalam penelitian ini adalah Family Business Community Universitas Ciputra dengan jumlah sampel yang berjumlah 93 orang, teknik pengambilan sampel yang digunakan dalam penelitian ini adalah purposive random sampling. Metode analisis data yang digunakan adalah Partial Least Square (PLS).
Hasil penelitian menunjukkan bahwa variabel Tingkat Kesiapan Suksesor berpengaruh positif dan signifikan terhadap Kinerja Perusahaan Keluarga; dan variabel Hubungan Antar Anggota Keluarga dan Bisnis berpengaruh positif dan signifikan terhadap Kinerja Perusahaan Keluarga.
PENGARUH KUALITAS PELAYANAN TERHADAP KEPUASAN MAHASISWA DI PTS X SURABAYA
Authors: Mardhotillah Rachma Rizqina , Rasyid Reizano Amri 
Published: February 2020

Perguruan Tinggi (PT) X merupakan merupakan salah satu Perguruan Tinggi Swasta yang terletak di Surabaya. Supaya eksistensi dan kualitas yang dimiliki terjamin, PTS X harus menjalankan riset terhadap kepuasan mahasiswa. Penelitian ini bertujuan untuk menguji pengaruh kualitas pelayanan terhadap kepuasan mahasiswa-mahasiswi di Universitas X di Surabaya. Variabel independen dalam penelitian ini adalah kulitas pelayanan dengan indikator Tangible, Reliability, Responsivenes, Assurance, Empathy, dan variabel dependen dalam penelitian ini adalah kepuasan mahasiswa-mahasiswi di Universitas X di Surabaya.
Penelitian ini merupakan jenis penelitian kuantitatif dengan metode survei, dimana peneliti yang menganalisis dengan angka-angka yang diperoleh dari hasil survey dalam bentuk menyebarkan kuesioner kepada para responden. Sampel penelitian dalam penelitian ini adalah mahasiswa/mahasiswi PTS.X di Surabaya sebanyak 200 orang. Teknik pengambilan sampel pada penelitian ini non-probability sampling dengan menggunakan teknik Quota sampling.
Hasil analisi menunjukkan bahwa Kualitas Pelayanan dengan indikator Tangible berpengaruh positif dan signifikan terhadap kepuasan. Kualitas Pelayanan dengan indikator Realibility berpengaruh positif dan tidak signifikan terhadap Kepuasan Mahasiswa. Kualitas Pelayanan dengan indikator Responsives berpengaruh positif dan signifikan terhadap Kepuasan Mahasiswa. Kualitas Pelayanan dengan indikator Assurance berpengaruh positif dan tidak signifikan terhadap Kepuasan Mahasiswa. Kualitas Pelayanan dengan indikator Empathy berpengaruh positif dan signifikan terhadap Kepuasan Mahasiswa di Universitas X di Surabaya.
خصائص توزيع كوماراسوامي الثنائي والمقارنة بين بعض طرائق تقدير معلماته
Authors: عبد احمد رزاق , شمال اياد حبيب 
Published: February 2020

ان التطور الحديث في علم الإحصاء جعل من التوزيعات الإحصائية محل انظار الباحثين خاصتاً في عملية التعويض عن بعض معلمات التوزيعات بقيم ثابتة والحصول على توزيع جديد، ففي هذا البحث تم دراسة توزيع كوماراسوامي وهو من التوزيعات المستمرة ثنائي المعلمات المحددة اذ تم التطرق الى خواص التوزيع من خلال عرض (دالة الكثافة الاحتمالية p.d.f، ودالة التوزيع التراكمية c.d.f.، والعزوم من الرتبة r، ودالة المعولية Reliability ودالة المخاطرة hazard).
اضافةً الى ذلك تم تقدير معلمات توزيع كوماراسوامي بطراق التقدير (MLE, ME, LSDE) من خلال استعمال أسلوب المحاكاة لأحجام عينات مختلفة وباستعمال قيم أولية للمعلمات وتم المقارنة بين طراق تقدير المعلمات على أساس متوسط مربعات الخطأ للمعلمات وكانت النتائج تدل على ان تقدير المعلمات بطرية الإمكان الأعظم MLE أفضل من مقدرات العزوم ME ومقدرات المربعات الصغرى المطورة LSDE.
Financing Schemes and Lost Profit Sharing in Islamic Banking : Challenges and Opportunities
Authors: Syarifuddin Syarifuddin 
Published: February 2020

A profit and lost sharing system is an agreement between a financier (shahibul mal) and a capital manager (mudharib) to run a particular economic business with a profit sharing and risk loss scheme. At this time a lot of literature encourages PLS schemes as the main mode of Islamic banking system, but in practice it is avoided. The research aims to theoretically evaluate the causes of PLS ​​contracts in Islamic banking fail to be fully accepted and be excellent for investors in Islamic Banking.
The results showed that the use of PLS ​​(mudharabah and musharakah) schemes in Islamic (sharia) Banking in Indonesia, Malaysia, Pakistan, Turkey and Morocco did show a low percentage of total financing. There are internal factors and external factors that hinder the development of PLS ​​schemes. Internal factors include moral hazard concern from partners, low trust in partners, weak monitoring systems, weak capabilities and collateral from partner companies. While external factors include; public literacy on Islamic banking products, government support, and supervision from regulators. Some of these factors arise because of a misunderstanding of the PLS system. Therefore, it is necessary to reprogram the perception of Shahibul mal and mudarib in the PLS scheme. This research is expected to contribute to the development and improvement of PLS ​​schemes in Islamic Banking.
Revisão Aberta
Authors: Varela Maria José Vilela de 
Published: February 2020

Apesar de os autores citarem a Medicina Tradicional Chinesa (MTC) e os distúrbios do sono2 como unitermos, os mesmos não foram referidos no resumo.Sugerimos que o façam pela importância destes temas no contexto da SPI. Ressaltamos, no entanto, que estes assuntos são encontrados no corpo do texto.
Funcionalidade de pessoas amputadas por acidentes de trânsito após adaptação protética
Authors: Dornelas Lílian de Fátima 
Published: February 2020

kruegereddy@gmail.com escheeren@gmail.com guinnn@gmail.com Introdução. Dentre as lesões decorrentes de um acidente de trânsito (AT), têm-se as amputações de membros e o objetivo de reabilitar estes indivíduos é proporcionar independência funcional. Objetivo. Conhecer a funcionalidade das pessoas amputadas por AT após adaptação protética. Método. Estudo de série de casos por meio de uma entrevista semi-estruturada, com 25 pessoas amputadas de membro inferior por AT após adaptação protética, que foram cadastradas no período de dezembro de 2002 a dezembro de 2004 na Associação de Assistência à Criança Deficiente de Minas Gerais (AACD/MG) e entrevistadas em maio e junho de 2005. Resultados. A maioria (15; 60%) dos participantes relatou utilizar a prótese somente para passeio, e todas as pessoas amputadas de membro inferior por AT após adaptação protética permaneceram com queixas funcionais como: andar em solo irregular (21; 75%), andar por longas distâncias (18; 64,3%) e subir degraus (16; 57,1%). Conclusão. Os pacientes amputados de membro inferior por AT utilizam a prótese comumente para passeio e, além disso, queixam de dificuldades funcionais que limitam às demandas do dia-a-dia. Sugere-se a necessidade de um processo de reabilitação voltado para a funcionalidade destes indivíduos, uma vez que, adquirir a prótese não é sinônimo de independência.
Saberes electromagnéticos asociados al funcionamiento del transformador en el cargador de un celular
Authors: Tejada Pérez Daniel , Daza Daza Jhonatan , De la Hoz Molinares Ever , Pacheco Fernández Juan 
Published: February 2020

El contenido de los cursos de física y en particular el curso de electromagnetismo, es presentado de forma aislada, con temas sin ninguna interacción y poca contextualización con el perfil profesional y con los avances tecnológicos de la sociedad actual. En búsqueda de mejorar la enseñanza de éste en el ciclo de ingeniería y licenciatura en Matemáticas y Física de la universidad del Cesar, el grupo de Investigación Educativa en Ciencias Naturales y Matemática ECINAMA, con sus semilleros de investigación FIEDUSICO Y PENSAGEO, propone una enseñanza de la física y la matemática a través de situaciones contextualizadas, con la finalidad de que los estudiantes apliquen los conocimientos y habilidades asociadas a situaciones, tales como el funcionamiento del cargador de un celular. En esta investigación se presenta la primera fase de los saberes asociados a la situación mencionada, mediante la pregunta problémica o generatriz: ¿Cómo funciona el cargador de un celular?
El funcionamiento del cargador de un celular contempla los siguientes procesos: transformación, rectificación, filtrado y regulación. El estudio involucra los saberes electromagnéticos asociados al proceso de transformación realizado por un transformador reductor monofásico del cargador de un celular. El diseño metodológico seguido en esta investigación consistió en: caracterizar el tipo de transformador de la mayoría de los cargadores de un celular, e identificar los fenómenos electromagnéticos presentes en su funcionamiento y determinar los saberes escolares que explican los fenómenos presentados.
A comparative evaluation of the effects on postoperative pain of systemic and topical forms of benzydamine hydrochloride after periodontal flap surgery: A randomized controlled clinical trial
Authors: Kocaman Gülhan 
Published: February 2020

Objective: The aim of this study was to evaluate comparatively the topical and systemic forms in the postoperative pain control periodontal flap surgery in spite of the daily dose of benzydamine hydrochloride spray form about one in twenty of the oral dose,.
Materials and Methods: In this randomized trial, the 48 systemic healthy individuals in need double-blind study with periodontal flap surgery were evaluated. Consent, demographic information and periodontal clinical parameters were obtained before surgery and periodontal flap surgery was performed with local anesthesia. The patients who underwent surgery were randomly assigned to two groups. One of the groups was prescribed tablet form of postopertive benzydamine hydrochloride and for the other was spray form as topical application. Postoperative pain was assessed by visual analog scale at 2, 6, 8, 12, 24 and 48 hours.
Results: There was no difference between systemic and topical drug groups in terms of demographic characteristics and periodontal clinical parameters. A statistically significant difference was found between 2 and 6 hours in favor of topical application. (p <0.05), but there was no significant difference in pain intensity at the 8th, 12th, 24th and 48th hours.
Conclusion: Although the topical form of benzydamine hydrochloride was 1/20 lower in postoperative pain control after periodontal flap surgery, it was found to be more effective in the early period compared to the systemic form, but equally effective in the late period. We premierly recommend that topical application should be preferred primarily in the prevention of overdose and toxicity in postoperative pain control after periodontal flap operation.
How is NLR and PLR affected in Type 2 diabetes mellitus compared to healthy population?
Authors: Dik Yavuz 
Published: February 2020

Objective: Diabetes Mellitus (DM); has become an important public health problem in Turkey and in the world. In this study, we aimed to investigate the effect of neutrophil / lymphocyte ratio and platelet / lymphocyte ratio in diabetic patients compared to healthy population in terms of cost effectiveness.
Material and Methods: A control group consisting of 82 diabetics and 85 healthy individuals who applied to the internal medicine outpatient clinic between January 2019 and November 2019 were included in the study. The patients were divided into two groups as those with diabetes and healthy individuals. Files were scanned retrospectively and hemoglobin, mean platelet volume (MPV), glycosylated hemoglobin (HbA1c), hematocrit counts (hct), neutrophil and lymphocyte counts, and neutrophil-lymphocyte ratio (NLR), platelet count (plt), platelet lymphocyte ratio (NLR) PLR) has been recorded.
Results: We retrospectively compared the demographic and laboratory parameters of the healthy group and the diabetic patients (82 patients and 85 healthy). The mean age of the diabetic group was 55.9 years, while the mean age of the healthy group was 37.5. Mean NLR was 2.4 and 2.1 in diabetic and healthy groups, respectively. NLR value was higher in diabetic group compared to healthy group and there was no statistically significant difference (p = 0.07). MPV values in diabetic group and healthy group were 8.53 and 8.51, respectively, and there was no significant relationship between them (p = 0.81). PLR value was 145.9 and 146.7 in diabetic group and healthy group, respectively, and we did not find any significant relationship (p = 0.97).
Discussion: As a result; In our study, when we evaluated the diabetic group within the diabetic group and the healthy group, we could not find a statistically significant relationship between the groups in terms of hematological parameters.
Hypothyroidism prevalence in pregnant women according to age groups
Authors: Çoşkun Buğra , Çoşkun Bora , Şehirli Kıncı Özge , Şimşir Coşkun , Pay Ramazan Erda , Karaşahin Kazım Emre 
Published: February 2020

Objective: Investigation of the thyroid function test (fT3, fT4 and TSH) results and the prevalence of overt/subclinical hypothyroidism according to age groups in patients who had applied to our hospital and diagnosed with pregnancy.
Material and Methods: Two thousand nine hundred and thirty-six women diagnosed with pregnancy for the first time upon seeing the fetal heartbeats with ultrasonography between January 2015 and December 2018, were included in our study. Patients were divided into 5 age groups, namely, the age groups of ≤18 years of age, 19-25 years, 26-35 years, 36-45 years and >45 years of age. The fT3, fT4 and TSH levels were statistically compared between all the patients and age groups.
Results: Two thousand nine hundred and thirty-six pregnant women were included in the study. The mean fT3 value was found as 3.180±0.519 (pg/mL), fT4 value as 1.051±0.258 (ng/d/L) and TSH value was found as 2.000±1.595 (mIU/mL) in all the population. The mean fT3, fT4 and TSH values were not statically different among the age groups (p=0.06, p=0.08 and p=0.829, respectively). No statistically significant differences were found among all the age groups as regards hyperthyroidism, euthyroidism, subclinical hypothyroidism and overt hypothyroidism (p=0.200).
Conclusion: Consistently with the previous studies in our country, the prevalence of subclinical hypothyroidism was found as high as 22.7% in our study. We think that scanning for hypothyroidism must be performed in the pregnancy period without discriminating between risk groups in our country, which is located in the iodine deficiency region. However, considering the different age groups, we believe that TSH levels must be measured with the same apprehensiveness for each age group since no statistically significant differences are found between age groups.
Identification of Possible Stellar Companions via Speckle Interferometry in a Sample of Be Stars
Authors: Souza T. B. , Guerrero C. A. , Borges Fernandes M. 
Published: February 2020

Abstract
We present speckle interferometric measurements of Be stars made with the 1.60 m Perkin-Elmer telescope at the Pico dos Dias Observatory of the Laboratório Nacional de Astrofísica in Brazil. Using three different filters (V, R, and I), we obtained astrometric measurements for 23 stars, during three observing runs allocated in 2017 March, 2018 April, and 2019 July. We identified pairs with angular separation ranging from 0.″10 to 6.″69, including six systems with separations smaller than 1.″0. We estimated a mean error in separation of 15 mas, 1.°2 in position angle, and 0.29 mag for the magnitude difference. We discovered three new possible double systems that are not identified in the literature: HD 174886, HD 159032, and HD 168135 with an average angular separation of 0.″20, 3.″23, and 5.″41, respectively. In addition, we identified four new pairs in multiple systems previously known in the Washington Double Star Catalog. However, for 16 stars of our sample, we did not find evidence of binarity, based on the diffraction-limited resolution, the field of view, and/or the sensitivity of our observations. From the cross-match with data from Gaia Data Release 2, we verified the possibility of some of these systems be gravitationally bound or not.