bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERCEPTION OF PRABUMULIH’VILLAGE INSTALLATION OF NATURAL GAS TO HOUSEHOLD
Authors: Hartono Deni Puji 
Published: March 2020

<p>This study aims to determine the public perception of the mounting Prabumulih’ Village natural gas for households in the District of West Prabumulih. This type of research method uses descriptive qualitative, and the subjects were 10 participants as informants. Data’collection that used through observation, interviews, and documentation. Data were analyzed using an interactive model that includes data reduction, presentation of data display, and verification. The research showed that 90% of public perception disclose the use of natural gas can save costs for fuel and then people do not have to suffer anymore looking for fuel if it runs out while cooking and get a clean fuel, environmentally friendly, so it’s good for health and safe.</p>
Team Approach: Pediatric Musculoskeletal Infection
Authors: Dhar Archana V. , Huang Craig J. , Sue Paul K. , Patel Karisma , Farrow-Gillespie Alan C. , Hammer Matthew R. , Zia Ayesha N. , Mittal Vineeta S. , Copley Lawson A. 
Published: March 2020

» A team approach is optimal in the evaluation and treatment of musculoskeletal infection in pediatric patients given the complexity and uncertainty with which such infections manifest and progress, particularly among severely ill children.» The team approach includes emergency medicine, pediatric intensive care, pediatric hospitalist medicine, infectious disease service, orthopaedic surgery, radiology, anesthesiology, pharmacology, and hematology.» These services follow evidence-based clinical practice guidelines with integrated processes of care so that children and their families may benefit from data-driven continuous process improvement.» Important principles based on our experience in the successful treatment of pediatric musculoskeletal infection include relevant information gathering, pattern recognition, determination of the severity of illness, institutional workflow management, closed-loop communication, patient and family-centered care, ongoing dialogue among key stakeholders within and outside the context of direct patient care, and periodic data review for programmatic improvement over time.» Such principles may be useful in almost any setting, including rural communities and developing countries, with the understanding that the team composition, institutional capabilities or limitations, and specific approaches to treatment may differ substantially from one setting or team to another.
Computer-Assisted Technologies in Arthroplasty
Authors: Hazratwala Kaushik , Brereton Sarah G. , Grant Andrea , Dlaska Constantin E. 
Published: March 2020

» Computer-assisted technologies that are used in arthroplasty include navigation, image-derived instrumentation (IDI), and robotics.» Computer-assisted navigation improves accuracy and allows for real-time assessment of component positioning and soft-tissue tension.» It is not clear whether the implementation of these technologies improves the clinical outcome of surgery.» High cost and time demands have prevented the global implementation of computer-assisted technologies.
E&P Notes (April 2020)
Authors: Rassenfoss Stephen , Feder Judy 
Published: March 2020

E&P Notes
Historic Oil Glut May Linger for Years
Stephen Rassenfoss, JPT Emerging Technology Editor
Editor’s Note: The global repercussions of COVID-19 and the oil price drop in mid-March continue to have far-reaching effects on the market, operators, and services companies. This month, JPT editors deliver in-depth E&P market and activity updates. To stay updated, visit the JPT website (www.spe.org/jpt), and sign up to receive JPT’s weekly newsletter (http://go.spe.org/jpt_newsletter) and JPT’s monthly Unconventional Insights newsletter ("http://go.spe.org/JPT_Unconventionals_Newsletter)"http://go.spe.org/JPT_Unconventionals_Newsletter).
Price crashes caused by supply gluts have been happening since oil production began, but the latest one is growing to epic proportions.
“There has been a dizzying drop in world oil demand and a dramatic pivot in Saudi oil production policy. If this situation persists amidst a recession, it points to the possible buildup of the most extreme global oil supply surplus ever recorded,” said Jim Burkhard, vice president and head of oil markets for IHS Markit.
The firm’s estimates of overproduction could range from 4 million B/D to 10 million B/D from February to May 2020, which is in line with a trend of growing oversupply estimates from oil industry observers, who say low prices will be long-lasting.
E&P Spending Cuts Spur Requests for Reduced OFS Fees
Judy Feder, Technology Editor
Fallout for the oil and gas industry from COVID-19 and the production volume war that began when Russia walked away from the suggested OPEC+ deal and Saudi Arabia started flooding the market with oil has been rapid and severe. And, it looks as if US shale will be the hardest hit. The total capital and operational expenditure of exploration and production (E&P) companies is now likely to be cut by $100 billion in 2020 and another $150 billion in 2021 if oil prices remain at a $30 level, according to a recent Rystad Energy impact analysis. The shale industry would carry the biggest burden of this supply shock by taking as much as $65 billion of the $100-billion 2020 spending reduction expected globally.
And, it may get worse. According to Rystad, if no agreement is reached during the next scheduled OPEC+ meeting in June, E&P companies are likely to slash capital and operational budgets to make up for significantly lower cash flows that are expected this year and next.
SPE Board Announces Nominees: 2022 President and 2021 Directors
Authors: Balboa Brian 
Published: March 2020

Kamel Ben-Naceur is the nominee for 2022 SPE President. He and seven others make up the new slate of nominees recommended for positions open on the SPE Board of Directors.
2022 SPE President
Kamel Ben-Naceur is CEO of Nomadia Energy Consulting, where he advises on sustainable energy policies and global/regional energy economics and outlooks. He has worked as a chief economist for a major oil and gas company and oilfield services company. Ben-Naceur has also worked as a director of the International Energy Agency and as an energy minister for the Tunisian government.
He is currently the chair of several SPE global committees, including Business Management and Leadership, the International Forum Series, and CO2 Capture and Storage. He has also taught several SPE courses on global energy, and strategic thinking and planning. He was technical director for Management & Information on the SPE International Board of Directors from 2008–2011. Ben-Naceur was also an SPE Distinguished Lecturer from 2009–2010 and received an SPE Distinguished Member Award and SPE Distinguished Service Award in 2014.
He has coauthored over 120 publications and 17 books.
Ben-Naceur holds a bachelor’s degree from the Paris Diderot University and a master’s degree from Ecole Polytechnique in Paris.
Growth Response of Greenhouse-Produced Muskmelon and Tomato to Sub-Surface Drip Irrigation and Soil Aeration Management Factors
Authors: Li Yuan , Niu Wenquan , Cao Xiaoshu , Zhang Mingzhi , Wang Jingwei , Zhang Zhenxing 
Published: March 2020

Abstract
Background: Hypoxia causes injury and yield loss. Soil aeration has been reported to accelerate the growth of plants and increase crop yield. The aim of this study was to examine growth response of greenhouse-produced muskmelon to 3 levels of sub-surface drip irrigation (I), 3 different installation depths of drip laterals in the soil (D), and 4 levels of supplemental soil aeration frequency (A). A fractional factorial experiment was designed to examine these treatment effects on marketable fresh fruit yield, leaf area index during 3 growth stages, and dry matter partitioning at harvest. In addition, we studied the response of fruit yield and dry matter of tomato to 2 levels of burial depths of subsurface tubing in combination with 3 frequency levels of soil aeration. Results: Results showed that soil aeration can positively influence the yield, leaf area index, dry matter and irrigation use efficiency of the muskmelon (p<0.05). The fruit yield of muskmelon and tomato were increased by 21.5% and 30.8% respectively with 1-d and 2-d aeration intervals compared with the no aeration treatment. Conclusions: The results suggest that soil aeration can positively impact the plant root zone environment and more benefits can be obtained with aeration for both muskmelon and tomato plants.
Detection of Cercopithifilaria bainae infection in shelter dogs and ticks in Oklahoma, USA
Authors: Lineberry Megan W. , Sundstrom Kellee D. , Little Susan E. , Stayton Erin M. , Allen Kelly E. 
Published: March 2020

Abstract
Background Cercopithifilaria bainae is a filarioid nematode of dogs. Infection with the parasite was not reported in the USA until 2017, when a dog with skin lesions in Florida was diagnosed. Brown dog ticks, Rhipicephalus sanguineus sensu lato, are the purported tick vectors, and are widespread in the USA. Therefore, C. bainae is likely present in additional states. Here, we tested dogs and ticks in Oklahoma for evidence of C. bainae infection. Methods Dermal punch biopsies were opportunistically collected from municipal shelter and client-owned dogs. Multiple skin samples collected from interscapular and head regions were tested by saline sedimentation to recover live microfilariae for morphometric identification and by PCR to amplify a 330 bp region of the filarioid 12S rRNA gene. Also, ticks observed on surveyed dogs were collected, identified to species level, and tested for filarioid DNA. Results A total of 496 saline sedimentations were performed on 230 shelter and 20 client-owned dogs. Cercopithifilaria bainae infections were identified in 2.6% (6/230) of shelter dogs by morphometry of microfilariae in sedimentations and/or amplification of DNA from skin. DNA sequences amplified from PCR positive skin samples were 99–100% identical to C. bainae reported in Italy. All skin samples from client-owned dogs were negative for filarioid infection by saline sedimentation and PCR. A total of 112 ticks, comprised of four species, were collected. Two of 72 R. sanguineus s.l., both engorged females found attached to a C. bainae infected dog, harbored C. bainae DNA (99–100% identity). One attached R. sanguineus s.l. male on the same dog harbored filarioid DNA sequence which was difficult to interpret at numerous base-pair locations, but was closest in identity (~80%) to C. bainae . Conclusions The distribution of C. bainae is more widespread than previously known. Here, we document C. bainae infections in dogs and DNA in brown dog ticks in Oklahoma for the first time. As brown dog ticks are commonly found throughout the USA, veterinarians in this region should consider C. bainae infection as a differential diagnosis in canine patients with dermatitis or polyarthritis.
Effects of Gastric Sleeve Surgery on the Serum Levels of GH, IGF-1 and IGF-binding Protein 2 in Morbidly Obese Patients
Authors: Al-Regaiey Khalid , Alshubrami Suad , Al-Beeshi Ibrahim , Alnasser Torki , Alwabel Abdulnasser , Al-Beladi Hassan , Al-Tujjar Omar , Alnasser Abdulrahman , Alfadda Assim , Iqbal Muhammad 
Published: March 2020

Abstract
Background Bariatric surgery is an effective treatment for severe obesity. It also ameliorates diabetes independently of weight loss through mechanisms that are not fully understood. In this study, we investigated the levels of GH, IGF-1 and IGF-binding protein (IGFBP-2) after gastric sleeve surgery in healthy obese individuals. Method This study was conducted in 33 obese (BMI >38.3) healthy male subjects aged 25 to 50 years undergoing sleeve gastrectomy. GH, IGF-1 and IGFBP-2 levels were evaluated by ELISA at baseline and 6-12 months after surgery. Other parameters, such as glucose, BMI, insulin, HOMA-IR and lipid profile, were also investigated. Results Systemic GH (12.32 vs. 50.97 pg/mL, p < 0.001) and IGFBP-2 levels (51.86 vs. 68.81 pg/mL, p < 0.001) were elevated after bariatric surgery. There was no change in IGF-1 level from before to after surgery. BMI (52.18 vs. 40.11, p = 0.001), insulin (19.35 vs. 8.80 mIU/L, p < 0.001) and HOMA-IR index (6.48 to 2.52, p < 0.001) were reduced after surgery. Lipid profile analysis revealed that total cholesterol (4.26 vs. 5.12 mmol/L, p < 0.001) and high-density lipoprotein (HDL) (0.90 to 1.55 mmol/L, p < 0.001) were increased, while triglycerides were decreased, after surgery (1.62 vs. 1.05 mmol/L p < 0.001). GH, IGF-1, and IGFBP-2 were not correlated with insulin or lipid parameters. Conclusions Our study suggests that improved circulating GH and IGFBP-2 levels may mediate the beneficial effects of gastric sleeve surgery in improving insulin sensitivity and reducing insulin demand.
Health-related quality of life among 13–14 year old adolescents with overweight - a mixed methods approach
Authors: Sundar Turid Kristin Bigum , Riiser Kirsti , Småstuen Milada , Opheim Randi , Løndal Knut , Glavin Kari , Helseth Sølvi 
Published: March 2020

Abstract
Background

Overweight and obesity are public concerns with risk of adverse health outcomes. Health-related quality of life (HRQoL) is lower in adolescents than children in general. An increase in body mass index (BMI) is associated with a decrease in HRQoL. The purpose of this study was to measure and explore the HRQoL among adolescents with overweight or obesity who had participated in an intervention study with the aim of increasing PA, reducing BMI and promoting HRQoL.

Methods

Mixed methods, with a convergent design, were used to investigate how different methodological approaches could expand our understanding of the adolescents’ HRQoL. Quantitative post-intervention data on HRQoL were collected among the 84 intervention participants, aged 13–14 years, using the KIDSCREEN 52 questionnaire. The data were compared with a Norwegian reference population of 244 individuals, and analysed using a non-parametric Mann-Whitney test. Qualitative semi-structured interviews were conducted with 21 adolescents from the intervention. A directed approach to content analysis was adopted, using the ten sub-scales from KIDSCREEN 52.

Results

HRQoL in the intervention sample was significantly reduced on the sub-scale of physical well-being compared to the reference population. The reference population scored significantly lower than the intervention sample on the sub-scale of parent relation and home life. No significant differences were found on the other sub-scales. The qualitative data supported the quantitative findings on the sub-scale of physical well-being, but showed that perceptions of fitness, energy level or health could vary. Regarding parent relations, the interviewees extended this to include relationships to other family members as equally important. Most of the interviewees expressed a negative view of their bodies, but not their clothing or accessories. This may explain why no statistically significant differences were found on these aspects in the results from the KIDSCREEN questionnaire.

Conclusion: The use of the KIDSCREEN 52 instrument gave important indications about the adolescents’ HRQoL. Combining methods enabled a comprehensive approach to research on HRQoL, indicating better ways of providing help. More research using the benefits of mixed methods approaches is needed to further elucidate these findings.
Transcriptome analysis reveals rapid defence responses in wheat induced by phytotoxic aphid Schizaphis graminum feeding
Authors: Zhang Yong , Fu Yu , Wang Qian , Liu Xiaobei , Li Qian , Chen Julian 
Published: March 2020

Abstract
Background

Schizaphis graminum is one of the most important and devastating cereal aphids worldwide, and its feeding can cause chlorosis and necrosis in wheat. However, little information is available on the wheat defence responses triggered by S. graminum feeding at the molecular level.

Results

Here, we collected and analysed transcriptome sequencing data from leaf tissues of wheat infested with S. graminum at 2, 6, 12, 24 and 48 hpi (hours post infestation). A total of 44,835 genes were either up- or downregulated and differed significantly in response to aphid feeding. The expression levels of a number of genes (9,761 genes) were significantly altered within 2 hpi and continued to change during the entire 48 h experiment. Gene Ontology analysis showed that the downregulated DEGs were mainly enriched in photosynthesis and light harvesting, and the total chlorophyll content in wheat leaves was also significantly reduced after S. graminum infestation at 24 and 48 hpi. However, a number of related genes of the salicylic acid (SA)-mediated defence signalling pathway and MAPK-WRKY pathway were significantly upregulated at early feeding time points (2 and 6 hpi). In addition, the gene expression and activity of antioxidant enzymes, such as peroxidase and superoxide dismutase, were rapidly increased at 2, 6 and 12 hpi. DAB staining results showed that S. graminum feeding induced hydrogen peroxide (H 2 O 2 ) accumulation at the feeding sites at 2 hpi, and increased H 2 O 2 production was detected with the increases in aphid feeding time. Pretreatment with diphenylene iodonium, an NADPH oxidase inhibitor, repressed the H 2 O 2 accumulation and expression levels of SA-associated defence genes in wheat.

Conclusions

Our transcriptomic analysis revealed that defence-related pathways and oxidative stress in wheat were rapidly induced within hours after the initiation of aphid feeding. Additionally, NADPH oxidase plays an important role in aphid-induced defence responses and H 2 O 2 accumulation in wheat. These results provide valuable insight into the dynamic transcriptomic responses of wheat leaves to phytotoxic aphid feeding and the molecular mechanisms of aphid-plant interactions.
Glucose transporter GLUT1 influences Plasmodium berghei infection in Anopheles stephensi
Authors: Wang Mengfei , Wang Jingwen 
Published: March 2020

Abstract
Background: Sugar feeding provides energy for mosquitoes. Facilitated glucose transporters (GLUTs) are responsible for the uptake of glucose in animals. However, the knowledge of GLUTs function in Anopheles mosquito is limited. Methods: Phylogenetic analysis of GLUTs in Anopheles stephensi (Asteglut) was performed by the maximum likelihood and Bayesian method. The spatial and temporal expression patterns of the four Astegluts were analyzed by qPCR. The function of Asteglut1 was examined using a dsRNA-mediated RNA interference method. Transcriptome analysis was used to investigate the global influence of Asteglut1 on mosquito physiology. Results: We identified 4 glut genes, Asteglut1 , Asteglutx , Asteglut3 and Asteglut4 in An. stephensi . Asteglut1, Asteglut3 and Asteglut4 were mainly expressed in the midgut. Plasmodium berghei infection differentially regulated the expression of Astegluts with significant downregulation of Asteglut1 and Asteglut4 , while upregulation of Asteglutx . Only knocking down Asteglut1 significantly increased the susceptibility of An. stephensi to Plasmodium berghei infection. This might be due to the accumulation of glucose prior to blood feeding in dsAsteglut1-treated mosquitoes. Our transcriptome analysis revealed that knockdown of Asteglut1 differentially regulated expression of genes associated with multiple functional clusters including detoxification and immunity. The dysregulation of multiple pathways might contribute to the increased P. berghei infection. Conclusions: Our study shows that Asteglut1 is essential in defense against P. berghei in An. stephensi . The regulation of Asteglut1 on vector competence might through modulating multiple biological processes, including detoxification and immunity.
Cost-effectiveness analysis of atezolizumab in advanced triple-negative breast cancer
Authors: Phua Lee Cheng , Lee Soo Chin , Ng Kwong , Aziz Mohamed Ismail Abdul 
Published: March 2020

Abstract
Background The IMpassion130 trial demonstrated that adding atezolizumab to nanoparticle albumin-bound (nab)-paclitaxel improved the survival of patients with untreated, advanced, programmed death ligand 1 (PDL1)-positive triple-negative breast cancer (TNBC). In view of the high cost of immunotherapy, it is important to examine its value with respect to both benefits and costs. In this study, the cost-effectiveness of atezolizumab/nab-paclitaxel combination therapy relative to nab-paclitaxel monotherapy was evaluated for the first-line treatment of advanced, PDL1-positive TNBC, from a healthcare system perspective. Methods A three-state partitioned-survival model was developed to compare the clinical and economic outcomes of treatment with atezolizumab/nab-paclitaxel combination therapy with nab-paclitaxel monotherapy in patients with advanced TNBC. Clinical data were obtained from the IMpassion130 trial and extrapolated to 5 years. Health state utilities were retrieved from the literature, while direct costs were sourced from public healthcare institutions in Singapore. The primary outcomes of the model were life years (LYs), quality-adjusted LYs (QALYs), costs and incremental cost-effectiveness ratios (ICERs). One-way and probabilistic sensitivity analyses and scenario analyses were conducted to explore the impact of specific assumptions and uncertainties. Results Adding atezolizumab to nab-paclitaxel resulted in an additional 0.361 QALYs (0.636 LYs) at an ICER of S$324,550 per QALY gained. The ICER remained high at $67,092 per QALY even when atezolizumab was priced zero. One-way sensitivity analysis showed that the ICER was most sensitive to variations in the cost of atezolizumab and the time horizon. Scenario analyses confirmed that the combination therapy was unlikely to be cost-effective even under extremely favourable assumptions. Conclusions Given the exceedingly high ICER, adding atezolizumab to nab-paclitaxel was unlikely to represent a cost-effective use of healthcare resources for the treatment of advanced PDL1-positive TNBC. Our findings will be useful in informing funding policy decisions alongside other considerations such as comparative effectiveness, unmet need and budget impact.
Perinatal listeriosis patients at a maternity hospital in Beijing, China
Authors: Li Chunyun , Zeng Huihui , Ding Xin , Chen Yi , Liu Xiaowei , Zhou Li , Wang Xin , Cheng Yumei , Hu Shanshan , Cao Zheng , Liu Ruixia , Yin Chenghong 
Published: March 2020

Abstract
Background: Listeriosis is a rare but severe emerging foodborne infectious disease. Perinatal listeriosis is extremely prone to causing septicaemia and CNS (central nervous system) infection, and serious adverse pregnancy outcomes (abortion and neonate death). This research reports perinatal listeriosis cases at a maternity hospital over the course of six years in Beijing, China.Methods: Beijing Obstetrics and Gynecology Hospital (BOGH) is the largest maternal and child health care hospital in China. We retrospectively searched all the laboratory confirmed 12 pregnancy-associated listeriosis cases during Jan 1, 2013 to Dec 31, 2018. The clinical manifestations, laboratory results, perinatal complications and outcomes were investigated.Results: In BOGH, 12 perinatal listeriosis cases were diagnosed based on Listeria positive culture, including 10 single pregnancies and 2 twin pregnancies, and the incidence of which is 13.7/100,000 deliveries (12/87,644). Among those cases, four pregnant women and four newborns had septicaemia, and two of the neonatal septicaemia also got CNS (central nervous system) infection. All the maternal patients recovered. For the fourteen offsprings, there were 8 newborns and 6 aborted fetuses, with two newborns died and 6 survived among the 8 newborns, and none of survivors had sequelae. The feto-neonatal fatality ratio is 57.1% (8/14).Conclusions: Perinatal listeriosis is associated with high morbidity and mortality. It has been confirmed that many factors contribute to the high mortality, such as high proportion of second trimester onset, empiric antibiotics with low pathogenic bacterium effective coverage.