bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the Interdisciplinary Nature of Precision Medicine：Network Analysis and Visualization
Authors: Xu Xin , Hu Jiming , Lyu Xiaoguang , Huang He , Cheng Xingyu 
Published: December 2020

Background
Interdisciplinary research is an important feature of precision medicine. However, the accurate cross-disciplinary status of precision medicine is still unclear.

Objective
The aim of this study is to present the nature of interdisciplinary collaboration in precision medicine based on co-occurrences and social network analysis.

Methods
A total of 7544 studies about precision medicine, published between 2010 and 2019, were collected from the Web of Science database. We analyzed interdisciplinarity with descriptive statistics, co-occurrence analysis, and social network analysis. An evolutionary graph and strategic diagram were created to clarify the development of streams and trends in disciplinary communities.

Results
The results indicate that 105 disciplines are involved in precision medicine research and cover a wide range. However, the disciplinary distribution is unbalanced. Current cross-disciplinary collaboration in precision medicine mainly focuses on clinical application and technology-associated disciplines. The characteristics of the disciplinary collaboration network are as follows: (1) disciplinary cooperation in precision medicine is not mature or centralized; (2) the leading disciplines are absent; (3) the pattern of disciplinary cooperation is mostly indirect rather than direct. There are 7 interdisciplinary communities in the precision medicine collaboration network; however, their positions in the network differ. Community 4, with disciplines such as genetics and heredity in the core position, is the most central and cooperative discipline in the interdisciplinary network. This indicates that Community 4 represents a relatively mature direction in interdisciplinary cooperation in precision medicine. Finally, according to the evolution graph, we clearly present the development streams of disciplinary collaborations in precision medicine. We describe the scale and the time frame for development trends and distributions in detail. Importantly, we use evolution graphs to accurately estimate the developmental trend of precision medicine, such as biological big data processing, molecular imaging, and widespread clinical applications.

Conclusions
This study can help researchers, clinicians, and policymakers comprehensively understand the overall network of interdisciplinary cooperation in precision medicine. More importantly, we quantitatively and precisely present the history of interdisciplinary cooperation and accurately predict the developing trends of interdisciplinary cooperation in precision medicine.
COVID-19 Misinformation Trends in Australia: Prospective Longitudinal National Survey
Authors: Pickles Kristen , Cvejic Erin , Nickel Brooke , Copp Tessa , Bonner Carissa , Leask Julie , Ayre Julie , Batcup Carys , Cornell Samuel , Dakin Thomas , Dodd Rachael H , Isautier Jennifer M J , McCaffery Kirsten J 
Published: December 2020

Background
Misinformation about COVID-19 is common and has been spreading rapidly across the globe through social media platforms and other information systems. Understanding what the public knows about COVID-19 and identifying beliefs based on misinformation can help shape effective public health communications to ensure efforts to reduce viral transmission are not undermined.

Objective
This study aimed to investigate the prevalence and factors associated with COVID-19 misinformation in Australia and their changes over time.

Methods
This prospective, longitudinal national survey was completed by adults (18 years and above) across April (n=4362), May (n=1882), and June (n=1369) 2020.

Results
Stronger agreement with misinformation was associated with younger age, male gender, lower education level, and language other than English spoken at home (P<.01 for all). After controlling for these variables, misinformation beliefs were significantly associated (P<.001) with lower levels of digital health literacy, perceived threat of COVID-19, confidence in government, and trust in scientific institutions. Analyses of specific government-identified misinformation revealed 3 clusters: prevention (associated with male gender and younger age), causation (associated with lower education level and greater social disadvantage), and cure (associated with younger age). Lower institutional trust and greater rejection of official government accounts were associated with stronger agreement with COVID-19 misinformation.

Conclusions
The findings of this study highlight important gaps in communication effectiveness, which must be addressed to ensure effective COVID-19 prevention.
AS PERGUNTAS DE SPOLIN
Authors: Pinto Davi de Oliveira 
Published: December 2020

A avaliação do jogo teatral efetuada mediante perguntas objetivas – procedimento característico da proposta pedagógica de Viola Spolin – é aproximada à leitura da cena. Alguns aspectos dessa avaliação são comentados, dentre esses, o pressuposto de que o professor não detém as respostas às questões que norteiam a leitura do jogo.
Palavras-chave: Spolin; perguntas; leitura
Parent and Pediatrician Preferences for Type 1 Diabetes Screening in the U.S.
Authors: Dunne Jessica L. , Koralova Anne , Sutphin Jessie , Bushman Jesse S. , Fontanals-Ciera Barbara , Coulter Joshua R. , Hutton Campbell T. , Rewers Marian J. , Mansfield Carol 
Published: December 2020

OBJECTIVE
The purpose of this study was to use a discrete-choice experiment methodology to understand the relative importance of the attributes of screening tests for type 1 diabetes among parents and pediatricians in the U.S.

RESEARCH DESIGN AND METHODS
Online surveys presented hypothetical screening test profiles from which respondents chose their preferred test profile. Survey attributes were based on likely screening test options and included the mode of administration, where and when the test was conducted, the type of education and monitoring available to lower the risk of diabetic ketoacidosis (DKA), and whether a treatment was available that would delay onset of insulin dependence. Data were analyzed using random-parameters logit models.

RESULTS
Parents placed the highest relative importance on monitoring programs that could reduce the risk of DKA to 1%, followed by treatment to delay onset of insulin dependence by 1 or 2 years, and, finally, avoiding a $50 out-of-pocket cost. Pediatricians placed equal importance on monitoring programs that reduced a patient’s risk of DKA to 1% and on avoiding a $50 out-of-pocket cost for the screening test, followed by the option of a treatment to delay the onset of insulin dependence. The mode of administration and location and timing of the screening were much less important to parents and pediatricians.

CONCLUSIONS
Parents and pediatricians preferred screening tests that were accompanied by education and monitoring plans to reduce the risk of DKA, had available treatment to delay type 1 diabetes, and had lower out-of-pocket costs.
Pagelaran Mamaca dan Proses Menjadi Manusia Madura
Authors: Hidayatullah Panakajaya 
Published: December 2020

Masyarakat Madura mewarisi tradisi sastra lisan yang sampai saat ini masih dipertahankan, yakni tradisi mamaca. Mamaca adalah salah satu seni tradisi yang hidup dalam masyarakat Madura sejak masuknya Islam ke Jawa dan Madura. Teks mamaca ada beragam jenisnya di antaranya yaitu Nor Bhuwwât (Kisah kanjeng Nabi Muhammad), Pandhâbâ (kumpulan cerita Pandawa), dan Juwâr Manik. Teks tersebut memiliki fungsi dan pemaknaannya sendiri. Biasanya pemilihan teks yang dibacakan menyesuaikan dengan konteks acaranya. mamaca biasa digunakan dalam dua jenis acara yakni acara yang bersifat sakral seperti Rokat Pandhâbâ (ruwat anak pandawa), Mèrèt Kandung (selamatan kehamilan), Molotan (peringatan maulud Nabi) dan Isra' Mi'raj (peringatan Isra' Mi'raj); serta acara yang bersifat profan yaitu kompolan mamaca (perkumpulan mamaca), arisan mamaca (arisan mamaca), dan hiburan. Bagi masyarakat Madura khususnya di Sumenep Madura, mamaca tidak hanya sekedar pagelaran seni semata namun sebuah proses untuk mengenali diri (Ngajhi Abâ’), mempelajari tatakrama (adhâb), internalisasi nilai-nilai Islam dan menjadi manusia Madura seutuhnya. Manusia Madura yang sopan, rendah hati, berbahasa halus, dan berserah diri. Perihal ini menarik untuk ditelaah, karena bertolak belakang dengan stereotype yang cenderung melekat pada masyarakat Madura sebagai masyarakat yang kasar, udik, suka berkelahi, dan keras kepala. Melalui pendekatan performance studies, pagelaran mamaca dapat ditafsir beberapa moda pertunjukannya (mode of performance) antara lain cara berpakaian yang menunjukkan simbol kehormatan dan relasi kuasanya, posisi pertunjukan, bentuk musikal yang lembut dan lambat, serta penggunaan beberapa perangkat pengeras suara yang mengingatkan akan nilai-nilai kehidupan dan sebagai simbol masyarakat komunal.

KATA KUNCI : tradisi lisan, mamaca, madura, pagelaran, sumenap
Revisiting the School-Based Management Recent Studies
Authors: Ya Kyaw Zay , Giatman Muhammad , Rizal Fahmi , Wulansari Rizky Ema 
Published: December 2020

This paper aims at reviewing the School-Based Management recent studies. As the research method, researcher follows the systematic procedures for literature review article such as collecting data, reviewing, categorizing, and presentation. This paper answers the three questions: (A) definition of SBM, (B) factors considered to implement SBM, and (C) the roles of practitioners. Data is based mainly on secondary data, published papers in the international journals in particular. In the findings, the researcher presents a certain definition of SBM defined by prior researchers, authority sharing, facility and infrastructure management, budget management, autonomy, transparency as well as the roles of school players, in-depth and breadth. Eventually, the recommendations are also appointed for further studies to promote the School-Based Management literature.
Strategi Terintegrasi untuk Pengelolaan Kawasan Cagar Budaya di Kota Surakarta
Authors: Krisnugrahanto Pratomo Aji , Zulkaidi Denny 
Published: December 2020

Abstract.
Every cultural heritage has different strategic management depends on its context. This research focused on the lack of good management strategy for Cultural Heritage Area in Surakarta City. The aims of this study is to formulate an integrated strategic management for cultural heritage areas in Surakarta City. This research used qualitative exploratory methodology with inductive approach. Primary data were obtained from field observations and interviews with sources related to cultural preservations, while secondary data were obtained from Surakarta City planning documents. The strategic management aimed for the community and government, therefore the internal variable is the condition of four aspects strategic management owned by the community and the city government, while the external variable is from outside the community and the city government. This research produces 73 strategy formulations which are summarized into 43 formulations based on the predicated similarity. The designation of strategy for managing Cultural Heritage Area is divided into two parts, which are 13 strategies for the scale of Surakarta City and 30 strategies for each region. Management integration can be seen from these strategies that are divided into each aspect to support the management of Cultural Heritage Area in Surakarta City.
Keywords: Strategic Management, Cultural Heritage Area, Surakarta City
Abstrak.
Setiap cagar budaya membutuhkan strategi pengelolaan yang berbeda sesuai dengan konteks cagar budaya. Keberadaan bangunan dan kawasan cagar budaya menjadi permasalahan tersendiri bagi perkembangan kota Surakarta. Sampai saat ini, kota Surakarta belum memiliki strategi pengelolaan kawasan cagar budaya yang terintegrasi. Penelitian ini merumuskan strategi pengelolaan kawasan cagar budaya yang terintegrasi di kota Surakarta. Metode penelitian yang digunakan adalah eksploratif kualitatif dengan pendekatan induktif. Data primer diperoleh dari observasi KCB dan wawancara dengan narasumber terkait cagar budaya, sedangkan data sekunder diperoleh dari dokumen perencanaan kota Surakarta. Strategi pengelolaan ditujukan masyarakat dan Pemerintah Kota Surakarta sehingga variabel internal adalah kondisi aspek strategi pengelolaan yang dimiliki masyarakat dan pemerintah kota, sedangkan variabel eksternal adalah kondisi aspek strategi pengelolaan dari luar masyarakat dan pemerintah kota. Penelitian ini menghasilkan 73 rumusan strategi yang kemudian diringkas menjadi 43 rumusan berdasarkan kesamaan predikat dan makna. Peruntukan strategi terbagi dalam 13 strategi pengelolaan kawasan cagar budaya untuk skala kota Surakarta, 30 strategi pengelolaan kawasan cagar budaya untuk setiap kawasan. Integrasi pengelolaan dapat diketahui dari adanya 17 strategi yang merupakan ringkasan dari 43 strategi dan digolongkan sesuai aspek pengelolaan kawasan cagar budaya.
Kata kunci: Strategi Pengelolaan, Kawasan Cagar Budaya, Kota Surakarta
Keterlibatan Komunitas Penggiat Budaya dalam Mengomunikasikan Nilai Srawung Berdasarkan Relief Candi
Authors: Kusumastuti Salma Fitri , Stefanie Yustina Dwi , Sandy Dwi Kurnia 
Published: December 2020

Abstract.
The value of srawung in Javanese society are slowly dying because of modernization. This value is related to harmony and respect to others, as can be seen in Ramayana reliefs from Candi Prambanan. Reliefs in the temple have been analysed by archaeologists through many researches and scientific books but at times, they are unable to deliver and communicate the value of srawung well. This research studied about how the heritage community conveys some research reports which contain important values to pursue a new relevant way of communicating its substantial value. The heritage community is partner to archaeologists, and also a part of society. So, with a role of heritage community, the value of srawung will be easily received by the people.
Keywords: Ramayana Relief, Srawung, Heritage Community
Abstrak.
Di era modern ini nilai-nilai srawung yang berkaitan dengan kerukunan dan sikap saling menghormati sudah mulai terkikis. Pada dasarnya, nilai ini merupakan nilai luhur dari masa lalu yang dapat ditelusuri, salah satunya melalui relief Ramayana di Candi Prambanan. Relief di Candi Prambanan sebenarnya sudah banyak dikaji oleh para peneliti Arkeologi, tetapi penyampaiannya kepada masyarakat masih belum maksimal. Karenanya, permasalahan yang dibahas dalam tulisan ini adalah bagaimana melibatkan komunitas untuk berperan menyampaikan hasil penelitian dari para peneliti yang mengandung salah satu nilai luhur yaitu srawung. Tujuannya adalah untuk mendapatkan cara baru dalam menyajikan hasil penelitian arkeologi dengan lebih relevan dan luwes sehingga mudah diterima masyarakat. Komunitas penggiat budaya dapat menjadi rekan bagi peneliti untuk menyampaikan hasil penelitian dengan cara-cara relevan dan sesuai dengan perkembangan zaman.
Kata kunci: Relief Ramayana, Srawung, Komunitas Penggiat Budaya
Benturan Kepentingan, Suatu Refleksi dalam Pengelolaan Warisan Budaya di Indonesia
Authors: Sulistyanto Bambang 
Published: December 2020

Abstract.
Conflict in this study is interpreted as a perception of differences in interests. The basic concept of this study departs from the view that conflict is a natural reality in human life that requires interaction with society. In general, this study aims to reveal the community's knowledge system in interpreting cultural heritage and ways to act using the knowledge system. As a consequence of the study, specifically, the purpose of this study is to diclose how to reduce the conflicts that often occur at various sites in Indonesia. The method used is explanatory qualitative explanatory which is an effort to understand why a phenomena can occur and what causes it. The results of this study find that cultural heritage conflicts should not be connoted as a negative phenomenon. Cultural heritage conflict is a reflection of the weakness of the management system that will be part of the solution to a problem that leads to a better change.
Keywords: Interaction, Society, Conflict, Heritage, Culture
Abstrak.
Konflik dalam nelitian ini diartikan sebagai persepsi mengenai perbedaan kepentingan. Konsep dasar penelitian ini berangkat dari pandangan, bahwa konflik merupakan realitas yang wajar dalam kehidupan manusia yang mengharuskan berinteraksi dengan masyarakat. Secara umum penelitian ini bertujuan mengungkapkan sistem pengetahuan masyarakat dalam memaknai warisan budaya dan cara-caranya bertindak menggunakan sistem pengetahuan tersebut. Sebagai konsekwensi atas kajian di atas, secara khusus tujuan penelitian ini mengungkapkn bagaimana upaya meredam konflik yang sering terjadi di berbagai situs di Indonesia. Metode yang digunakan adalah eksplanatif kualitatif eksplanatitif yakni upaya memahami mengapa fenomena dapat terjadi dan apa faktor penyebabnya. Hasil penelitian ini menyatakan konflik warisan budaya tidak harus dikonotasikan sebagai fenomena yang negatif. Konflik warisan budaya merupakan merupakan cermin lemahnya sistem pengelolaan yang akan menjadi bagian dari solusi atas suatu permasalahan yang mendorong ke arah perubahan yang lebih baik.
Kata kunci: Interaksi, Masyarakat, Konflik, Warisan, Budaya
Eigen Problem Over Max-Plus Algebra on Determination of the T3 Brand Shuttlecock Production Schedule
Authors: Permana Andra , Siswanto Siswanto , Pangadi Pangadi 
Published: December 2020

The production process is included in the Discrete Event System (DES). The DES independent variable generally depends on the event, so an event is influenced by the previous event. Max-plus algebra can be applied in the DES problem to change the system of nonlinear equations obtained into linear equations. Max-plus algebra is a set of real numbers combined with equipped with operations max and plus ⊗ or can be denoted with . An effective and efficient production process needs to pay attention scheduling steps well. The purpose of this research is to determine the Shuttlecock T3 production schedule using eigenvalue and eigenvector in max-plus algebra. The research method in this research is study of literature and observation. Literature study is carried out by studying references about max-plus algebra, especially material related to scheduling problems, while observation are carried out in the process of taking data of the Shuttlecock T3 production process in Surakarta. The linear equation system that is formed based on the results of the observation is then presented in the form and . The periodic time and initial system production time are determined from the eigenvalue and eigenvector matrix where . The results of the research showed that the production system run periodically every 249 minutes, then the best time for each processing unit to start working can be determined, as well as the Shuttlecock T3 production schedule according to the working hours more effective and efficient can be determined too.
PEMANFAATAN ROTAN SEBAGAI KERAJINAN OLEH MASYARAKAT DI DESA EMBALA KECAMATAN PARINDU KABUPATEN SANGGAU
Authors: Veneranda Venena , Oramahi H A , Idham M 
Published: December 2020

Indonesian forests have abundant non-timber forest products. In Embala Village, rattan is a potential biological wealth. Rattan is usually used by the community as a material for plaiting, rigging, and other purposes. The study aims to describe how the use of rattan and to record the types of rattan from handicrafts by the people of Embala Village, Parindu District, Sanggau Regency. Research methods are carried out by surveys and interview. Data retrieval uses purposive sampling techniques to determine respondents. The result showed that there are 10 types of rattan commonly used by the community in Embala Village, that is: Korthalsia rigida Blume, Calamus javensis Blume, Daemonorops geniculata (Griff) Mart, Calamus caesius Blume, Korthalsia echinometra Beccari, Calamus inops Becc, Calamus manan Miq, Calamus trachycoleus Becc, Daemonorops Melanochaetes Blume, Daemonorops didymophylla Mart. From 10 rattan produces 21 form of handicraft in the form of jarai, bakol, tomikng, raga, oyok podi, pongonae sidu, pongomat tilap, kobab, soo’, pingat, pongampe podi, koranyak, korosah, sapu, simpae, solongko, juah, lokar, jampot, kanol, ntudok. The resulting woven has different uses according to the shapes and size produced such as jarai used to transport firewood from the forest and bakol is used to wash rice into the river.Keywords: Craft, Public, Rattan.
Inhibition of SARS-CoV-2 Main Protease: A Repurposing Study That Targets the Dimer Interface of the Protein
Authors: Pekel Hanife , Ilter Metehan , Sensoy Ozge 
Published: December 2020

Coronavirus disease-2019 (COVID-19) was firstly reported in Wuhan, China, towards the end of 2019, and, unfortunately, within a short period of time, emerged as a pandemic. The spread and lethality rates of the COVID-19 have ignited studies that focus on the development of therapeutics for either treatment or prophylaxis purposes. In parallel, drug repurposing studies have also come into prominence. In this study, we aimed at having a holistic understanding of conformational and dynamical changes induced by an experimentally characterized inhibitor on main protease (M-pro) which would enable the discovery of novel inhibitors. To this end, we performed molecular dynamics simulations using crystal structures of apo and α-ketoamide-13b-bound M-pro homodimer. Analysis of trajectories pertaining to apo M-pro revealed a new target site, which is located at the homodimer interface, next to the catalytic dyad. Thereafter, we performed ensemble-based virtual screening by exploiting the ZINC and DrugBank databases and identified three candidate molecules, namely eluxadoline, diosmin, and ZINC02948810 that could invoke local and global conformational rearrangements which were also elicited by α-ketoamide-13b on the catalytic dyad of M-pro. Furthermore, ZINC23881687 was also discerned as a promising candidate due to its interaction with catalytically important residues Glu166 and Ser1. Last but not least, we could find another candidate, namely ZINC20425029, whose mode of action was different. It modulated the dynamical properties of catalytically important residue, Ala285 rather than the catalytic dyad. As such, this study presents valuable findings that might be used in the development of novel therapeutics against SARS-CoV-2 M-pro.