bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatio-temporal analysis of Deaths from carbon monoxide poisoning in Iran between 2011 and 2018- An ecological study
Authors: Alimohamadi Yousef , Rahimi Danial , Mehri Ahmad 
Published: January 2020

Abstract
Background Carbon monoxide (CO) poisoning, as one of the lethal poisoning, is responsible for a large percentage of poisonings and accidental deaths. Since the investigation of the mortality and the distribution of CO poisoning deaths in Iranian provinces is still unknown and no study has investigated so far, this study was conducted to determine the trend of mortality rate changes due to CO poisoning by Spatio-temporal analysis in Iran from 2011 to 2018. Methods An ecological study was conducted based on data from the reports of at the National Center for Statistics of Iran for eight years from 21 March 2011 to 21 March 2018. The number of deaths due to CO poisoning and the annual mortality rates of CO poisoning per 100,000 population were calculated. The Spatio-temporal analysis used to determine the spatial and temporal distribution of deaths. Results A total of 6078 deaths were reported due to CO poisoning that 4497 death were male (74%) and 1596 were female (26%) from 2011 to 2018. In both sexes, the mortality rate due to CO poisoning was 1.26 from 2011 to 0.91 in 2018. According to the results, the overall male-to-female ratio was 2.8. The mortality rate due to CO Poisoning had a decreasing trend. However, this trend did not have a linear trend (p=0.37). Our results showed that most of the deaths due to CO poisoning are higher in the northern and western provinces of Iran. Conclusion This study is one of the first studies to compare the spatial and temporal mortality rates due to CO poisoning in Iran. Paying attention to general education about the principles of safety in the installation of heaters and the use of the gas networks, continuous and accurate monitoring of the installation and operation of CO-producing, and the use of sensitive alarms can reduce mortality and morbidity due to CO poisoning.
Efficient long fragment editing technique enables rapid construction of genetically stable bacterial strains
Authors: Huang Chaoyong , Guo Liwei , Wang Jingge , Wang Ning , Huo Yi-Xin 
Published: January 2020

Abstract
Background Bacteria are versatile living systems that enhance our understanding of nature and enable biosynthesis of valuable molecules. Long fragment editing techniques are of great importance for accelerating bacterial chromosome engineering to obtain desirable and genetically stable strains. However, the existing genomic editing methods cannot meet the needs of researchers. Results We herein report an efficient long fragment editing technique for complex chromosomal engineering in Escherichia coli. The technique enabled us to integrate DNA fragments up to 12 kb into the chromosome, and to knock out DNA fragments up to 187 kb from the chromosome, with over 95% positive rates. We applied this technique for E. coli chromosomal simplification, resulting in twelve individual deletion mutants and four cumulative deletion mutants. The simplest chromosome lost a 370.6 kb DNA sequence containing 364 open reading frames. In addition, we applied the technique to metabolic engineering and constructed a genetically stable plasmid-independent isobutanol production strain that produced 1.3 g/L isobutanol via shake-flask micro-aerobic fermentation. Conclusions These results suggested that the technique is a powerful chromosomal engineering tool, highlighting its potential to be applied in different fields of synthetic biology.
Ethnomedicinal study of Plants in Wonchi District, South Western Shewa, Oromia Regional State, Ethiopia
Authors: Dida Getu , Warkineh Bikila , Lulekal Ermias , Demissew Sebsebe 
Published: January 2020

Abstract
This study documents indigenous medicinal plant utilization, management and the threats affecting them. The study carried out in Wonchi District from December to March 2017. Ethnomedicinal data were collected using semi-structural interview, Field observation, Preference and Direct matrix ranking with traditional healers. The Ethnomedicinal use of 68 plant species belonging to 62 genera and 34 families. was documented in the study area. The most commonly used plant families were Lamiaceae 9 species, 13.23%) followed by Asteraceae (8, 11.76%).Most of the plants (70.6%) were reportedly used to treat human diseases. The most frequently used plant parts were leaves (66%), followed by roots (17.64%).The dominant route of remedy administration was oral (38 preparations, 55.9%) followed by dermal (20, 29.4%), nasal (8, 11.8%) and optical (2, 3%). The study showed that Wonchi District is rich in medicinal plant and related indigenous knowledge. However, anthropogenic factors and very poor conservation efforts threaten medicinal plant survival in the study area. Promotion a complementary in-situ and ex-situ conservation strategy for medicinal plants of the District highly recommended.
Germinal Ovarian Tumors In Reproductive Age Women: Fertility-Sparing And Outcome
Authors: Dellino Miriam , Silvestris Erica , Loizzi Vera , Paradiso Angelo , Cormio Gennaro 
Published: February 2020

Abstract
Purpose MOGCTs (malignant ovarian germ cell tumours) is a rare tumour, which mainly affects patients in reproductive age. The aim of this study is evaluate the fertility and survival outcomes in young women with MOCGTs treated with fertility-sparing surgery (FFS).Methods From 2000 to 2018 twenty-eight patients with diagnosis of MOGCTs in reproductive age at the University of Bari were collected. Most received FFS and in patients treated conservatively, the reproductive outcome and survival were investigated. Data of patient demographics, clinical presentation, oncology markers dosage, staging, type of surgery histological examination, survival and reproductive outcome were collected from hospital and office charts. All informed consent was obtained from all patientsResults Twenty-eight patients with diagnosis of MOGCTs were collected. The median age was 24 (range: 9-45). The majority of the patients had stage IIIC. Twenty-four woman received fertility-sparing surgery consisting in unilateral ovariectomy and omentectomy whereas only 4 women based on their stage (IIIC) received a radical surgery (hysterectomy with bilateral adnexectomy, lymphadenectomy and omentectomy). Our study shows that FFS in MOGCTs can produce good results both on reproductive outcomes and on survival. Indeed, in our group there was only one case of exitus as result of recurrence. On the other side, patients after FFS maintained normal ovarian function and 5/5 women who have looked for pregnancy, obtained it spontaneously. The median follow-up was 90 moth (range 3-159).Conclusion Conservative surgery for MOGCTs should be considered for women in the reproductive age group who desire preservation of fertility.
Magnitude and associated factors of prelacteal feeding practices among mothers of under one-year-old children in Rural Pastoralist Communities of Afar, North Eastern Ethiopia: A community based cross-sectional study.
Authors: desta helen tkuwab , Berhe Kidanemaryam , Gebremedhin Gebretsadkan , Mohammed Hajira , Gebremariam Abebe , Mulugeta Afework 
Published: February 2020

Abstract
Background In Ethiopia, inappropriate feeding including prelacteal feeding is one of the immediate causes of undernutrition. The objective of this study was to assess the magnitude and associated factors of prelacteal feeding practices among mothers of children aged less than one year in Rural Pastoralist Communities of Afar, Ethiopia. Methods A cross-sectional study was conducted in the Afar Region, Ethiopia from May to June 2016. A total of 424 mothers were included in the study. A two-stage cluster sampling technique was used to select sample clusters and households. A pre-tested and structured questionnaire was used as a data collection instrument. SPSS version 25 was used to analyze the data. Model goodness of fitness was assessed using Hosmer and Lemeshow test. Multi-collinearity between independent variables was checked. Binary logistic regression analysis was used to identify the association between the explanatory variables and prelacteal feeding practices. Multivariable logistic regression was also used to determine the independent predictors of prelacteal feeding practices. Result In this study, 75.7% (95% CI 71.1%, 79.7%) of mothers gave prelacteal feeds to their newborns. The odd of prelacteal feeding was 2.32 times higher in mothers whose husbands didn’t attend formal education as compared to their counterpart (AOR = 2.32, 95% CI: 1.18-4.5). The odds of prelacteal feeding was 7 times higher for infants delivered at home compared to infants delivered at a health facility (AOR = 7.52, 95% CI:3.44, 16.45). Fail to have skin to skin contact between the mother and the newborn increases the odds of prelacteal feeding by 5 times than their counterparts (AOR=5.12, 95%CI: 2.14, 12.21). Conclusion Three-fourth of the children in Rural Pastoralist Communities of Afar received prelacteal feeding. Home delivery, husband education and skin to skin contact immediately after birth were found to be independent predictors of prelacteal feeding in the pastoralist communities. Strengthening the behavior change communication on optimal infant and young child feeding, promotion of husband education and institutional delivery and skin to skin contact immediately after birth are the recommendations.
Channeling the Right Path-to-care: Improving Religious Leaders’ Knowledge and Beliefs about Suicide Prevention in South West Nigeria
Authors: Ogbolu Raphael E. , Ijadunola Macellina Y. , Adepoju Oladipo A. , Ola Bola A. , Quadri-Asorona Bukola , Ogundiran Abdurrahman , Akinyemi Patrick Ayodeji , Alaba Oluwatoyin A. 
Published: February 2020

Abstract
Background In African societies, the path-to-care that the ill and their relatives seek via consultation of traditional and religious healers is related to the concept of the causation, nature and origin of mental illness. There is a shortage of mental health personnel and facilities in Nigeria; hence, alternative healthcare providers such as Religious Leaders are often sought first. This intervention research was conducted with the aim of improving knowledge, beliefs and practices of Religious Leaders in relation to depression and suicide and their understanding of their role in suicide prevention. Methods This comparative cross sectional study with 102 Religious Leaders was conducted in two states in South West Nigeria. Religious Leaders were invited for a day medico-religious training on depression and suicide prevention among their congregation. Measures for inclusion comprised of correctly filled and completed semi-structured questionnaires pre and post training. Results Out of 102 Religious Leaders, 58.8% were 50 years and above, 76.5% were males. The average years of clerical experience as Religious Leaders was 15.9 years. Most of them (82.4%) had no previous training in suicide prevention and the average congregation size of Religious Leaders in Lagos was larger than Ile-Ife (256 vs 113). Only a few Religious Leaders (21.6%) counseled at least an individual with suicidal thoughts, 3 months preceding the training, while most (57.8%) of them noted that there are penalties for members of their congregation who attempted or died by suicide. The average knowledge score at pretest and post-test were 3.37 and 5.98 respectively out of a total score of 8. Percentage difference in knowledge scores from pretest to post-test showed a drop in low and fair scores by 19.6% and 54.9% respectively and an increase in good and very good scores by 46.1% and 28.4% respectively. Conclusion The outcome of this intervention in improving Religious Leaders’ knowledge about depression being a medical condition and major contributor to suicide has far-reaching implications on suicide prevention. In particular, through their involvement in this medico-religious collaboration, Religious Leaders have the right information required to preach and counsel towards encouraging their congregation to seek appropriate mental health care.
MAN-MADE LANDFORMS IN LANDSCAPE DESIGN OF TERRITORIES AS A MEANS OF SOLVING ENVIRONMENTAL PROBLEMS
Authors: BONDARENKO Iryna , KOKHAN Natalia , GONCHAR Olena , BONDARENKO Bohdan 
Published: February 2020

Abstract
The paper is devoted to the role of man-made landforms in landscape design as a means of solving a range of environmental problems. This paper gives a characteristic of man-made landforms. The use of artificial forms of relief as a means that allows evoking bright emotions in the viewer is actualized. Such objects as Mill Creek Canyon (USA), Heart of Reeds (Great Britain), Devil’s Lake (USA), Buitenschot (Holland), Landform Ueda (England) and Crawick Multiverse (Scotland), created by famous artists and designers were considered in the course of the analysis. In their landscape organization manmade landforms play the leading role, the use of which has opened up the possibility of solving a number of environmental problems. As a result, it was established that the formation of compositions from earthen embankments allows overcoming problems of regulating water balance of territories, contributing to protection from excessive noise loads, as well as becoming a tool for rehabilitation of former industrial territories.
PRUITT IGOE VS CITY OF THE FUTURE
Authors: GĄSOWSKA-KRAMARZ Agata 
Published: February 2020

Abstract
The idea of a modernist housing estate was aimed at determining the development of the current cities of the future. The idea developed throughout modernism gave justification for the statement that housing estates were intended to provide all the comforts to its inhabitants, but did not secure an ideal life. Something that was supposed to be clean and obvious did not come true. Attempts to secure a perfect space for the inhabitants contributed to the idea of a city of the future within our reach. Such utopian modernist settlements gave grounds for further developments involving intelligent settlements, cities of the future, living organisms with a central nervous system, capable of collecting and processing all information. The analysis presents a comparison of a housing estate and a city, the first of which became the base for the development of the other one.
SELECTED PROBLEMS INVOLVING THE PRESERVATION OF HISTORICAL FRAME BUILDINGS IN SILESIA IN THE CONTEXT OF THEIR FUTURE THERMO-RENEWAL
Authors: SZYMANOWSKA-GWIŻDŻ Agnieszka , ORLIK-KOŻDOŃ Bożena , STEIDL Tomasz 
Published: February 2020

Abstract
The paper discusses the conservation state of selected examples of historical objects preserved in the Silesia Province, having a complex structure with the elements of Prussian wall. They can be found mainly in the so-called company towns created in the late 19th century. The work presents the structural and architectural details characteristic for such objects, with the emphasis on different technical condition of the structural and finishing elements. External envelopes were evaluated in terms of their thermal insulation and humidity condition, depending on their structure, type of material and location, using theoretical and calculation methods. Due to historical value of the buildings and special character of the façade, the paper suggests that the material values, thermal conductivity and humidity level of the envelopes should be closely identified to provide a basis for further analyses.
MODELLING OF THE AIRFLOW IN THE PASSENGER COACH
Authors: SARNA Izabela , PALMOWSKA Agnieszka 
Published: February 2020

Abstract
In this paper currents requirements of HVAC designing (Heating, Ventilation and Air Conditioning) in railway vehicles have been presented. The data were based on railway standards [1, 2].
The aim of this study was to carry out the numerical calculation of airflow combined with heat exchange in a passenger coach. ANSYS CFX 12.1 software was used to carry out the simulation. Two cases of boundary conditions were considered, the first obtained from design calculations common for ordinary buildings and information included in standards and the second only based on the information included in standards. After analysing of the results, it was found that the distribution of air velocity in a coach was similar in both cases, average air velocity was 0.79 m/s. However, the distribution of air temperature was different. For case 1 the average indoor air temperature was 25.07°C and for case 2 was 23.53°C. The method of determining the heat solar gains had a great impact on the results. A further possibility of a model improvement was indicated for example human models will be introduced in coaches, in order to verify the conditions of their thermal comfort, and air recirculation.
A review of nature-based solutions for resource recovery in cities
Authors: Kisser Johannes , Wirth Maria , De Gusseme Bart , Van Eekert Miriam , Zeeman Grietje , Schoenborn Andreas , Vinnerås Björn , Finger David C. , Kolbl Repinc Sabina , Bulc Tjaša Griessler , Bani Aida , Pavlova Dolja , Staicu Lucian C. , Atasoy Merve , Cetecioglu Zeynep , Kokko Marika , Haznedaroglu Berat Z. , Hansen Joachim , Istenič Darja , Canga Eriona , Malamis Simos , Camilleri-Fenech Margaret , Beesley Luke 
Published: February 2020

AbstractOur modern cities are resource sinks designed on the current linear economic model which recovers very little of the original input. As the current model is not sustainable, a viable solution is to recover and reuse parts of the input. In this context, resource recovery using nature-based solutions (NBS) is gaining popularity worldwide. In this specific review, we focus on NBS as technologies that bring nature into cities and those that are derived from nature, using (micro)organisms as principal agents, provided they enable resource recovery. The findings presented in this work are based on an extensive literature review, as well as on original results of recent innovation projects across Europe. The case studies were collected by participants of the COST Action Circular City, which includes a portfolio of more than 92 projects. The present review article focuses on urban wastewater, industrial wastewater, municipal solid waste and gaseous effluents, the recoverable products (e.g., nutrients, nanoparticles, energy), as well as the implications of source-separation and circularity by design. The analysis also includes assessment of the maturity of different technologies (technology readiness level) and the barriers that need to be overcome to accelerate the transition to resilient, self-sustainable cities of the future.
Single Nucleotide Polymorphism Analysis in HIV and Kaposi's Sarcoma Disease by Microarray Technique
Authors: Koyuncu Ismail , Gönel Ataman , Ozcan Emrah , Temiz Ebru , Toprak Şahin , Akkafa Feridun , Binici Irfan 
Published: January 2020

Background:
Emergence of Kaposi's Sarcoma in the cases other than HIV, following the
use of immunosuppressant drugs, demonstrates that it is related to weak immunity. The fact that this
malignancy does not occur in every HIV-positive patient suggests that genetic predisposition may
also be effective. Replacement of one of the base pairs of adenine, guanine, cytosine, and thymine
that constitute the DNA sequence in the human genome with another base pair can affect susceptibility
to disease, response to treatment, and immunity.

Objective:
The purpose of this study is to analyze the Single Nucleotide Polymorphism that could
predispose to Kaposi's sarcoma of an HIV-infected patient and to identify which nucleotides such
SNPs correspond to, using the microarray technology.

Material and Method:
The blood samples of individuals, one of whom was diagnosed with Kaposi's
Sarcoma HIV (+) visiting the outpatient clinic of infectious diseases polyclinic of Harran University
Research and Practice Hospital and of a healthy individual with no Kaposi's Sarcoma, were
used in the study. Following the DNA isolation of the blood samples taken from the respective individuals,
a SNP analysis was conducted on the microarray device. 204,000 SNPs obtained were
scanned later on in the databases in an attempt to identify the SNPs related to Kaposi's Sarcoma.

Results:
In the 204,000 SNP screenings, we scrutinized the SNPs that differ in the case of Kaposi's
Sarcoma [KS (+) and HIV (+)] on the basis of Control [KS(-) and HIV(-)] and HIV+ [KS(-)], and
two SNPs of the ENDRA gene, three SNPs of the ADRA1A gene, six SNPs of the STIM1 gene,
four SNPs of the EFNB2 gene, and one SNP of the CD209 gene were found to be different. However,
when it comes to all SNPs (all the 204.000 SNPs) screened in terms of allele, it was observed
that the AA and BB alleles were lower in the patient with Kaposi's Sarcoma [KS (+) and HIV (+)]
compared to other groups and AB alleles were found to be higher than others in the patient with Kaposi's
sarcoma [KS] (+) and HIV (+)].

Conclusion:
In the microarray study we have conducted, 204,000 SNPs were screened for Control
(HIV-) HIV (+) and HIV (+) patient with Kaposi's Sarcoma. It was found that 32,362 of those SNPs
had different alleles in the Kaposi's Sarcoma [KS + HIV (+)] patient, while they had the same ones
in the control [KS (-) and HIV (-)] and HIV + [KS (-)] group. 16 of the 32,362 SNPs took place
among the genes related to Kaposi's Sarcoma. In the cases of Kaposi's Sarcoma with suspected diagnosis,
it can be used as a beneficial laboratory test.
O sistema tributário: a equidade e as perspectivas de crescimento e descentralização
Authors: Da Silva Martins Ives Gandra 
Published: February 2020

O texto analisa o sistema tributário nacional, identifica seus principais problemas, situa as propostas e discussões que vêm sendo apresentadas nos últimos anos e sugere uma proposta de reforma para conformação de um novo sistema tributário para o país. Paralelamente, aprofunda as discussões sobre a questão da Federação e das formas de compensar os efeitos de mudanças nas suas esferas de competência.
Balanço e perspectivas do federalismo fiscal no Brasil
Authors: Do Desenvolvimento Administrativo Fundação 
Published: February 2020

O projeto "Balanço e Perspectivas do Federalismo Fiscal no Brasil” tem por objetivo analisar os determinantes da crise da federação em suasvárias dimensões. São abordados nos diversos subprojetos temas como o sistema tributário, os fluxos funanceiros públicos, a distribuição de competências na execução das políticas sociais, a análise da dimensão histórica do federalismo brasileiro, entre outros.
Perfil intra-empreendedor: um estudo inicial em funcionários da Infraero-sede
Authors: Pessoa Eliana , Oliveira Kelly Cristina Nóbrega 
Published: February 2020

Considerando os conceitos de intra-empreendedorismo e sua importância para as organizações atualmente, realizou-se pesquisa juntos aos ocupantes do cargo de Profissional de Serviços Aeroportuários (PSA), na sede da Empresa Brasileira de Infra-Estrutura Aeroportuária (Infraero), buscando verificar se eles possuem ou não perfil intra-empreendedor. Utilizou-se um questionário, composto de 28 questões referentes às necessidades e habilidades indispensáveis ao desenvolvimento do intra-empreendedorismo, para avaliar o perfil dos funcionários, bem como levantar as características que apareceram com maior e menor freqüência na amostra selecionada. Como resultado, concluiu-se que a maioria dos empregados pesquisados possui perfil intra-empreendedor, porém necessitando do desenvolvimento de outras características, tais como necessidade de independência e de auto-realização, também imprescindíveis. Foram sugeridas, também, ações que podem ser adotadas na organização para incentivar os trabalhadores a exercer suas capacidades empreendedoras.Palavras-chave: intra-empreendedorismo; capacidade empreendedora; perfil intra-empreendedor; Infraero.