bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiological profile of pain and non-steroid anti-inflammatory drug use in collegiate athletes in the United States
Authors: Christopher Shefali , Tadlock Bailey A , Veroneau Bryanna J , Harnish Christopher , Perera Nirmala KP , Knab Amy M , Vallabhajosula Srikant , Bullock Garrett Scott 
Published: June 2020

Abstract
Background: Although athletic endeavours are associated with a high amount of physical stress and injury, the prevalence of pain is underreported in the sports medicine literature with only a few studies reporting pain on collegiate athletes or exploring sex difference of pain. Impact of pain on athlete availability, training and performance can be mitigated when key epidemiological information is used to inform adequate pain management strategies.To 1) provide an epidemiological profile of self-reported pain experienced by the National Collegiate Athletic Association (NCAA) athletes by sex during the first half of the 2019 season, 2) describe their self-reported non-steroidal anti-inflammatory drug (NSAID) use.Methods: Online survey was completed by athletes at three NCAA institutions from 1 August to 30 September 2019. Descriptive statistics were used to describe player demographic data, self-reported pain and self-reported NSAID use. Pain incidence proportion were calculated.Results: 230 female athletes and 83 male athletes completed the survey. Self-reported pain incidence proportion for female athletes was 45.0 (95% CI 41.5-48.5) vs 34.9 (95% CI 29.4-40.4) for male athletes. Majority of the athletes did not report pain (55% female vs 62% male) during the first half of the 2019 season. Female athletes reported pain in their back (35%), knee (26%), and ankle/foot (23%) whilst male athletes reported pain in their knee (35%), back (28%), and shoulder (24%). Of all athletes, 28% female vs 20% male athletes reported currently taking NSAIDs. Of athletes that reported pain, 46% female vs 38% male athletes currently took NSAIDs. 70% female vs 61% male athletes self-purchased NSAIDs, and 40% female vs 55% male athletes consumed alcohol.Conclusions: Half of female athletes and one in three male athletes reported pain. Back, knee and foot/ankle pain and knee, back and shoulder pain is common in female and male athletes respectively. One in four female athletes and one in five male athletes use NSAIDs for pain or prophylactic purpose. Majority self-purchase these medications indicating need for health literacy interventions to mitigate potential adverse effects.
Partner’s Emotional Reaction to Pregnancy Mediates the Relationship Between Pregnancy Planning and Prenatal Mental Health
Authors: Kazemi Ashraf , Ghaedrahmati Maryam , Kheirabadi Gholamreza 
Published: June 2020

Abstract
Background: An unplanned pregnancy may follow by increasing depression and anxiety and the aim of the present study was to evaluate the mediating role of partner’s emotional reaction to pregnancy (PERP) on the relationship between pregnancy planning and prenatal mental health. Methods: This cross-sectional study was conducted on 303 healthy Iranian pregnant women during their third trimester. The levels of depression and anxiety were measured using the Edinburgh Postnatal Depression Scale and the State-Trait Anxiety Inventory. Further, the PERP score was measured using a researcher-made questionnaire. The data were analyzed using the plug-in application PROCESS macro. Results: The results showed that PERP score was related to pregnancy planning and prenatal depression and anxiety inversely. The effect of the pregnancy planning on depression (β=-1.603; CI: -2.276 to -.978) and anxiety (β=-1.950, CI: -3.717 to -.493) were significant only with mediating role of PERP. Conclusions: The results indicated that the effect of the pregnancy planning on prenatal mental health is mediate by PERP and in unplanned pregnancy, women need to receive their positive partner’s reaction toward pregnancy to preserve their mental health.
Estimation of COVID-19 outbreak size in Harbin, China
Authors: Song Haitao , Jia Zhongwei , Jin Zhen 
Published: June 2020

Abstract
Background: Since the first level response to public health emergencies (FLRPHE) was launched on January 25, 2020 in Heilongjiang province, China, the outbreak of COVID-19 seems to be under control. However, an outbreak of COVID-19 caused by imported case developed in Harbin during April 2020. Here, we provide an estimate of the COVID-19 outbreak size in Harbin in April based on the number of found infected cases, assess the proportion of found and unfound infected cases in infected cases and evaluate the effective reproduction number which shows the transmission risk of COVID-19. Methods: We used data from April 9 to April 30, 2020, on the number of found infected cases from the outbreak in Harbin to infer the number of infections in Harbin in the outbreak of COVID-19 and give the proportion of found and unfound infected cases in infected cases. Data on found infected cases were obtained from the the reports of Health Commission of Heilongjiang Province. A Susceptible-Unfound infected-Found infected-Removed model was used to fit the data on found infected cases of COVID-19 in Harbin using the least square method and simulate the transmission of COVID-19. The effective reproduction number was estimated. Results: The COVID-19 outbreak size estimated in Harbin in April reaches 174, where 54% of infected cases were found and 46% of infected cases were not found out. Our findings suggest that the effective reproduction number decreased drastically in contrast with the value of 3.6 on April 9 after that the effective interventions were implemented by Heilongjiang province government. Finally, the effective reproduction number arrived the value of 0.04 which is immensely below the threshold value 1, which means that Heilongjiang province government got the outbreak of COVID-19 in Harbin under control. Conclusions: The COVID-19 outbreak size in Harbin based on the assumptions that infected people with COVID-19 in the incubation period have the same infectivity with infectious people with COVID-19 could have been overestimated. As an increasing number of imported infected cases got into China and a growing number of asymptomatic infected people were found, our study provides evidence that unfound infected cases would increase the risk of local outbreak of COVID-19 in China.
Clinical Significance of Monitoring Circulating Free DNA and Plasma Heat Shock Protein 90alpha in Patients with Esophageal Squamous Cell Carcinoma
Authors: Zhao Qiang , Miao Congxiu , Lu Qingpu , Wu Weipeng , He Yuan , Wu Shouxin , Liu Huimin , Lian Changhong 
Published: June 2020

Abstract
Background: Esophageal squamous cell carcinoma (ESCC) is the predominant histological type of esophageal cancer in China and has an extremely poor prognosis. Circulating free DNA (cfDNA) and plasma heat shock protein 90alpha (Hsp90a) are two novel noninvasive biomarkers for diagnosis and prognostic prediction of several types of cancer. However, to the best of our knowledge, the roles of the two biomarkers in ESCC are still unknown.Methods: We recruited 93 primary ESCC patients and detected plasma concentrations of the two markers at different time points, including 1–3 days pre-chemotherapy, 1–7 days pre-surgery and 7–14 days post-surgery. Baseline concentrations of the two markers were associated with main characteristics of ESCC patients which were collected at first diagnosis. Correlation between the two markers and traditional serum biomarkers at baseline was also examined. Furthermore, dynamic changes of the cfDNA and Hsp90α concentrations among different time points and the potential clinical significance were assessed.Results: There was no significant association between baseline concentrations of the two markers and clinical features. Especially, cfDNA demonstrated stronger correlation with other circulating biomarkers than Hsp90α at baseline level. Importantly, both cfDNA and Hsp90α concentrations were significantly increased after surgery. Kaplan-Meier survival analysis showed that a change in concentration of cfDNA (ΔcfDNA) but not Hsp90α (ΔHSP90ɑ) between pre-surgery and post-surgery had significant effect on the overall survival of surgical patients with ESCC. Thus, ΔcfDNA evaluation could be a promising prognostic marker for surgical ESCC patients.Conclusions: Our findings may improve the understanding of the function of cfDNA and Hsp90α in ESCC.
Adverse Reproductive Outcomes Associated with Teenage Pregnancy in three Maternity Hospitals in Asmara, Jan 01 – DEC 31, 2018
Authors: Asrat Daniel Tikue , Beloweden Eden Hagos , Teklay Hana Andeberhan , Tesfamaryam Luwam Solomon , Weldemaryam Ruth Zeragaber , Teweldebrhan Samuel Sibhat , Gebreweldi Frezghi Hidray , Gebregziabher Nahom Kiros , Giliu Samson Mehari 
Published: June 2020

Abstract
Background: The highest rate of teenage pregnancy in the world is in sub Saharan Africa. Thus, out of the twenty countries with the highest rate of teen marriage, Eritrea ranked fourteenth. This aim of this study was to assess adverse outcomes associated with teenage pregnancy. Methods: A retrospective cohort study was followed for 424 nulliparous pregnant women between the age of 14 and 24 years. The maternity clinical record was used to review data on maternal spontaneous abortions, preterm birth, method of delivery, postpartum hemorrhage, perineal laceration, baby weight, Apgar score at 5 minute and congenital anomalies were taken as our variables of interest. Moreover, face-to-face interview was conducted to enlighten the socio demographic characteristics, circumcision status of the mother and antenatal care visits during their last pregnancy. Descriptive and inferential data was analyzed using SPSS version 20. Chi-square test and bivariate logistic regression were also used.Results: The socio demographic characteristic of the study shows that the educational status of teenage mother was low compared to adult mothers; in addition unmarried teenage mothers were high compared to adult mothers. In this study teenage mothers had significantly higher anemia, preterm delivery, Post partum hemorrhage and low birth weight babies as compared to the adult mothers. Also the study revealed that compared to adult mothers, teenage mothers had significantly higher abnormal delivery mode with low Apgar score among teenage mothers.Conclusions: In this study adolescent pregnancy was found to be associated with increased outcomes of anemia, preterm birth, low birth weight, abnormal delivery and post-partum hemorrhage. Even though preeclampsia and Apgar score were not significantly different between adolescents and adult mothers this should not be ignored and just bypass it not as adverse outcomes of teenage.
Expanding the Reach. Traditional Ecological Knowledge And Technological Intensification in Beekeeping Among The Ogiek of Mau Forest, Kenya
Authors: Zocchi Dauro Mattia , Volpato Gabriele , Mutiso Duncan Chalo , Mutiso Patrick Chalo , Fontefrancesco Michele Filippo 
Published: June 2020

Abstract
BackgroundInitiatives for the promotion and intensification of beekeeping through the introduction of modern beehives are taking place in East Africa and elsewhere where beekeeping has been a long-standing livelihood practice. When innovations are introduced into people’s livelihoods and culture, they can trigger multiple changes, aligned or not with the original intentions. We carried out fieldwork in the Eastern part of the Mau Forest Complex, focusing on beekeeping activities among Ogiek beekeepers involved in a project aimed at promoting honey production through the modernization of the apiculture sector. The main aim of the study was to explore the relationships, tensions and complementarity of traditional and modern knowledge and practices and the ways in which they are employed in beekeeping strategies among the Ogiek, as well as to reflect on the changes that this intensification process triggers in the livelihoods of the Ogiek and in their relationship with Mau ForestMethodsWe conducted semi-structured interviews and free listing exercises with 30 Ogiek beekeepers. Other methods included guided field walks in apiaries and participant observation. We collected ethnobotanical data about the flora used in beekeeping and ethnographic information on traditional practices of apiary management and honey harvesting and storing.Results We report 66 species that are important for beekeeping purposes in 6 main use categories, namely melliferous species, and species used for making hives, placing hives, attracting bees, harvesting and storing honey. Our study reveals that the Ogiek still possess detailed knowledge of the forest’s flora and its importance and uses. At the same time, they have moved beekeeping out of the forest into open areas of pasture and crop fields, adopting modern beekeeping techniques. The two beekeeping systems have complementary roles in the livelihoods of the Ogiek and rely on different paths of knowledge transmission and on different plant species. We highlight that modern and traditional beekeeping respond to the challenges and requirements of different ecological settings.ConclusionsOur study indicates a complementarity of traditional and modern beekeeping and associated knowledge and practices within the livelihoods of the Ogiek, but it also suggests that the process of honey production intensification, by decoupling beekeeping from the forest, may weaken the relationship between the Ogiek and the forest, thus impairing the Ogiek’s role as guardians of the forest, and eroding beekeeping-associated TEK. Further studies should target the promotion of forest beekeeping via the intensification of log hive production and valorisation of forest honey and associated TEK as well as floristic diversity.
Measuring Patient Satisfaction in an Outpatient Psychiatric Clinic. What Factors Play a Role?
Authors: Romanowicz Magdalena , Oesterle Tyler , Croarkin Paul E. , Sutor Bruce 
Published: June 2020

Abstract
IntroductionPatient satisfaction is defined as the perception that one’s general health care needs are being met. Prior research suggests that positive patient satisfaction with health care facilitates the physician-patient relationship and enhances the quality of life. Unfortunately, little is known about what factors play a role in influencing patient satisfaction. Objective The primary purpose of this study was to assess patient satisfaction (as measured by the PSQ-18 Patient Satisfaction Questionnaire) of patients seen by general psychiatry residents and to examine what factors might impact patient satisfaction. A secondary purpose was to explore the effects of (three one hour sessions) mentalization skills training on the physician-patient relationship and patient satisfaction. We hypothesized that depressive and anxiety symptoms would negatively impact patient satisfaction. We hypothesized that patients’ satisfaction scores would improve if care was provided by residents who completed mentalization training.MethodsThis was a prospective case-control study, enrolling adult patients (n = 157) referred for psychiatric assessment in a psychiatric resident outpatient clinic. The Short Form PSQ-18 for patients was the primary outcome variable and was compared to Patient Health Questionaire (PHQ-9) and anxiety Generalized Anxiety Disorder 7-Item scale (GAD-7) questionnaires. Outcome data from the PSQ-18 was compared among residents who either had or had not completed mentalization training. The data were analyzed with univariate analyses and to test multiple linear regression. ResultsOverall the patients were satisfied with clinician communication and interpersonal manner (PSQ-18 average scores of 4.21 +/- 0.66 and 4.15+/-0.69 respectively). The patients score on PHQ-9 was inversely related to their scores on time spent (TS) [p = 0.01] and accessibility/convenience (AC) [0.0009] subscale of patient satisfaction. GAD-7 score was inversely related to patients scores on AC subscale (p = 0.01). In regards to mentalization training, there was no difference in IRI (Interpersonal Reactivity Index) scores between the groups aside from Perspective taking (PT) subscale ( p = 0.029). Conclusions Our study reveals that depression and anxiety can negatively impact PSQ-18 patient scoring in psychiatric outpatients seen for the first time in a resident clinic. However, this study failed to show that a brief mentalization- based training could improve patient satisfaction scores that were already quite high at baseline.
Examining Long-Term Effects of Human Papillomavirus Vaccine Recommendation Messages: A 4-Month Follow-up Survey of a Randomized Controlled Study in Japan
Authors: Okuhara Tsuyoshi , Ishikawa Hirono , Ueno Haruka , Okada Hiroko , Kiuchi Takahiro 
Published: June 2020

Abstract

Background: We previously conducted a randomized controlled study to examine persuasive messages recommending HPV vaccination to mothers with daughters in September 2017 in Japan. Our previous study showed that the three types of intervention message used (statistical information only, a patient’s narrative in addition to statistical information, and a mother’s narrative in addition to statistical information) all significantly improved mothers’ intention to have their daughter(s) receive the HPV vaccine, in comparison with mothers who received no messaging. The present study is a follow-up survey to assess the long-term effect of the intervention in our previous study.Methods: Four months after the initial study, in January 2018, participants in the previous study were contacted and queried about their current intention to have their daughter(s) receive the HPV vaccine. Statistical analysis was conducted using the paired t-test and analysis of variance.Results: A total of 978 mothers participated in the current survey. Vaccination intention 4 months after intervention had decreased to a level that did not differ significantly from the level prior to intervention in all three intervention conditions. The amount of change in vaccination intention 4 months after intervention did not differ significantly among the three intervention groups (p=0.871).Conclusions: A single exposure to messaging was insufficient to produce a persistent intervention effect; repeated exposure to messaging coupled with other interventions may be important.
Clinical Characteristics and Predictors of Mortality for Young Adults with Severe COVID-19: A Retrospective Study
Authors: Lu Yanjiao , Huang Zhenli , Wang Meijia , Tang Kun , Wang Shanshan , Gao Pengfei , Xie Jungang , Wang Tao , Zhao Jianping 
Published: June 2020

Abstract
Background and objective: Little is yet known whether pathogenesis of COVID-19 is different between young and elder patients. Our study aimed to investigate the clinical characteristics and provide predictors of mortality for young adults with severe COVID-19.Methods: A total of 77 young adults with confirmed severe COVID-19 were recruited retrospectively at Tongji Hospital. Clinical characteristics, laboratory findings, treatment and outcomes were obtained from electronic medical records. The prognostic effects of variables were analyzed using logistic regression model.Results: In this retrospective cohort, non-survivors showed higher incidence of dyspnea and co-existing laboratory abnormalities, compared with young survivals in severe COVID-19. Multivariate logistic regression analysis showed that lymphopenia, elevated level of d-dimer, hypersensitive cardiac troponin I (hs-CTnI) and high sensitivity C-reactive protein (hs-CRP) were independent predictors of mortality in young adults with severe COVID-19. Further analysis showed that severely young adults with two or more factors abnormalities above would be more prone to death. The similar predictive effect of above four factors had been observed in all-age patients with severe COVID-19.Conclusion: Lymphopenia, elevated level of d-dimer, hs-CTnI and hs-CRP predicted clinical outcomes of young adults with severe COVID-19.
Analysis of microbial changes in the rhizosphere of unplanted and planted Atractylodes lancea via high-throughput sequencing
Authors: Xu Yan , Niu Junfeng , Chen Lijun , Wu Xiaoqiang , Dong Zhongmin , wang zhezhi 
Published: May 2020

Abstract
Background

Atractylodes lancea is a traditional Chinese medicine, which typically requires more than 3–4 years of continuous cropping to obtain the underground medicinal components. With continuous cropping years, the quality and yields of A. lancea medicinal materials decrease, while pests and diseases increase. These aspects are intimately correlated with rhizospheric microorganisms.
Methods

This research paper employed high-throughput sequencing for its detection in soil that was cultivated for three years and never cultivated to clarify the relationship between the microbial diversity of the rhizosphere and continuous A. lancea cropping.
Results

The rhizosphere microbial community was altered following the continuous cropping of A. lancea. The bacterial diversity and richness were observed to decrease, while the fungal community diversity increased, and richness decreased. The total OUTs of the soil bacteria and fungi of unplanted and planted A. lancea were 59.58% and 37.65%, respectively. At the phylum level, the relative abundance of Proteobacteria, Gemmatimonadetes, Acidobacteria and Chloroflexi decreased, whereas the relative abundance of Mortierellomycota increased. At the genus level, Bradyrhizobium, Striaticonidium, Dactylonectria, Sphingomonas, Burkholderiaceae, Rhodanobacter, Arthrobacter, Scleroderma, Mortierella and Penicillium were significantly different between the two sample groups.
Conclusions

Our results revealed that following the cultivation of A. lancea, the rhizospheric microbial community was altered. This study preliminarily determined the