bluuebunny/crossref_metadata_2025_split huggingface dataset:
Septic shock: perspective methods of diagnostics and therapy based on immunopathogenesis
Authors: Gomanova L. I. 
Published: May 2020

Based on the III International Consensus on the definition of Sepsis and Septic Shock (Sepsis-3), the modern definition of septic shock was proposed: “Septic shock is a type of sepsis that is accompanied by severe hemodynamic, metabolic and cellular disorders, and these disorders are associated with a higher risk fatal outcome”. Despite the classic idea of septic shock development (proinflammatory, immunosuppressive phases and, finally, multiple organ failure with distinct shock organs), the theory of activation of the caspase, endocannabioid system and system of protein of programmed death-1 in evolving septic shock are promising approaches to development of new diagnostic and therapeutic methods. Lymphopenia is already observed at an early stage of septic shock, which further leads to deep immunosuppression. Previous experimental studies have revealed some treatment methods to reduce the pro-inflammatory stage, which, however, did not show desired results in clinics. Now it is necessary to look for ways to inhibit apoptosis, depletion of lymphocytes, macrophages and other immune cells in the course of septic shock. It is known that caspases mediate innate detection of pathogenic microorganisms, cause pyroptosis, activation of monocytes. It has been proven that inhibition of caspase-8, caspase-11 leads to decreased monocyte functioning and cytokine release, which plays an important role in immunopathogenesis of septic shock. Associations of PD-1 and PD-2 expression on CD4+ lymphocytes and monocytes are also shown to be connected with immune dysfunctions, decrease in lymphocyte proliferation, and increased interleukin-10 concentration. Stimulation of the cannabinoid receptors is able to reduce inflammation by inhibiting cytopathic and immunosuppressive effects of pathogens. It has been shown that classic septic shock biomarkers (pro-inflammatory, anti-inflammatory cytokines; procalcitonin, lactate, etc.) do not have predictive power in relation to the outcome of the disease. Circulating and citrullated histones, determined by mass spectrometry, may serve as potential diagnostic markers of septic shock, but they require further study. Use of oxidized phospholipid oxPAPC (Oxidized 1-palmitoyl-2-arachidonoyl-snglycero-3-phosphocholine), hydrogen sulfide and Fasciola hepatica fatty acid binding proteins (hepatic fluke) prevents oxidative stress, synthesis of pro-inflammatory cytokines and provides maturation of macrophages and dendritic cells. Further study of immunological reactions during septic shock is of great importance for substantiation of new approaches to the diagnostics and therapy of septic shock.
Habitat use and food habitats of a gecko population in a west African suburban area
Authors: Amadi Nioking , Gladstone Golden Chizi , Wala Chimela , Vignoli Leonardo , Ugbomeh Adaobi , Dendi Daniele , Luiselli Luca 
Published: May 2020

1.The spatial and trophic ecology of Afrotropical gecko populations are poorly known. Here, we report ecological observations on Brook’s House Gecko (Hemidactylus angulatus), a widespread gekkonid species, in the Rivers State University of Science and Technology campus, Port Harcourt, Nigeria.2. A total of 488 gecko individuals were recorded during the present study, in two surveyed habitat types: (i) plantationm trees (PTH) and (ii) buildings (BDH). In PTH, they were observed in 13 out of 15 species of trees present in the study area, with their (log) frequency of sightings being positively correlated to the (log) frequency of surveyed trees per species.3. The geckos used substantially the non-native ornamental trees of the PTH habitat. Pinus ponderosa and Elaeis guineensis were significantly preferred by geckos over all the other tree species.4. Geckos also used frequently the buildings (BDH habitat) at the university campus. There was no correlation between (log) area of each building and (log) number of observed lizards.5. We collected faeces from 51 gecko individuals in dry season and 66 in wet season. There were no significant dietary differences between seasons, with Diptera and adult Lepidoptera dominating in the diet.6. Dietary habits of geckos differed significantly between habitat types, with Araneae and Lepidoptera (larvae) being eaten much more frequently in BDH, and in Coleoptera and Isopoda that were eaten much more frequently in PTH The diversity dietary metrics (Shannon and Dominance indices) were very similar either between seasons or between habitats.7. Our independent set of analyses (diet diversity metrics; contingency tables on taxonomic dietary composition and rank-abundance diagrams) showed that lizards exhibited a same feeding strategy in both wet and dry seasons as well as in the two habitat types, although the diet composition differed significantly between habitats.8. A “mixed” foraging strategy was apparently used by Hemidactylus angulatus at the study area, as also observed in other gekkonid species from elsewhere.
Biomass gasification under external heating and using steam as a gasifying agent: Numerical analysis
Authors: Lenis-Rodas Yuhan Arley , Maag Gilles , Lins de Oliveira Celso Eduardo , Corredor Lesme Antonio , Sanjuan Marco Enrique 
Published: May 2020

Gasification using an external heat source is considered as a high potential alternative to take high moisture content biomass into a fuel gas. This gas could reach energy densities close to 12 MJ/Nm3, which allows its use as a fuel in conventional thermal machines or as a precursor for higher fuel gases. Given this, in the present work allothermal gasification for a 50 %w.t. moisture content biomass was analyzed computationally aiming to yield a high hydrogen content syngas.
Using a power supply of 8 kW, the dry tar-free gas yield was around 51.9 mol/kg of biomass with an average concentration of 45.7% CO, 44.8% H2, 4.8% CH4 and 4.6% CO2. A peak temperature of 1070 K and 33% for chemical efficiency were achieved. In spite of using homogeneous heating along the reactor wall, the process temperature decreases near the gas outlet. This is due to solid material depletion decreasing the process thermal inertia. During the final stages, H2 and CO concentration also record an increase due to the endothermic carbon gasification as well as water-gas shift and methanation reactions.
ORAL MANAGEMENT OF PATIENTS WITH CANCER
Authors: Lopez Silva Claudia Patricia , Wei Ting Mathew Albert , Sundaresan Pritam Daniel , Borromeo Gelsomina 
Published: May 2020

The oral management of individuals affected by medical conditions, including those with a current cancerdiagnosis, is often complex and as such should be provided by either experienced dentists or dental specialists (e.g. Special Needs Dentists) with adequate training and experience. Patients with cancer needearly dental intervention as the cancer itself or its therapy may place them at increased risk of systemic andoral complications.
In Colombia, Special Needs Dentistry (SND) has not been formally recognized as a specialty and doesnot form part of the current dental curricula suggesting a paucity of suitably qualified dentists to providecomplex oral care for oncology patients. While it is accepted that general dentists will provide the bulk ofcare to these individuals, their knowledge base is unclear. This paper aims to improve the knowledge basearound complex SND by addressing the oral complications faced by this patient cohort and how to prioritizetreatment, together with proposing a simple protocol to streamline coordination of care between the dental,allied health and medical teams, that is, through a multidisciplinary approach. It is important to acknowledgethat dentists have a role at all three levels of the multidisciplinary management of canc
TRANSFORMATION OF THE NURSES LEARNING FOR COMPETENCE DEVELOPMENT AND IMPROVEMENT
Authors: Jankovska Livija 
Published: May 2020

Transformation of the learning environment is an important factor for the innovation of the educational process. Contemporary educational paradigm requires new approaches which promote complicated and multidisciplinary competencies. Professional development of nurses depends on acquisition of new and more complicated cognitive, psychomotor and affective competencies to meet the contemporary needs of the medical care. Analyses of the empirical research results reveals that students evaluate their professional practical skills not very high that proves the need of closer connection of the theory and corresponding practice in order students can acquire high quality integrative competences, which prepare for professional, social and personal challenges. Affective competences are playing major role in modern health care but the teachers’ questionnaire data show that students underestimate attitudes for their professional life. Thus, attitude forming is an important task of nurses’ education. One more factor is to prepare nurses for digital changes in Latvia medical system that requires integrative solutions for the multifunctional, active, information technology and practice oriented learning and teaching. Content and structure of new didactic models should promote interactive, technology improved and work-based learning process in order to provide sustainable education.
PROFESSIONAL SELF-CONSCIOUSNESS OF STUDENTS OF A PEDAGOGICAL UNIVERSITY: RESULTS OF THE RESEARCH
Authors: Bugaychuk Tatyana , Koryakovtseva Olga , Rubleva Olga , Burakova Galina 
Published: May 2020

The article is devoted to the study of the formation of professional self-consciousness of a student - a future teacher, with an emphasis on the features of professional self-esteem as an element of professional self-consciousness. The data obtained in the article using the methods of studying professional self-esteem and professional self-knowledge allow us to pay attention to the complex procedure of entering the profession by students of a pedagogical university, passing through the crises of vocational training at 2 and 5 courses, 3rd and 4th year students are completely ready to study, work, accumulate knowledge and develop in a wider professional sense, they have a focus on self-development. The dynamics of development of students’ ideas about themselves at different stages of studying at university are shown, the emphasis is on the features of formation of professional self-esteem of future teachers. The study opens up significant prospects for advanced training and improving the quality of students' training, taking into account the characteristics of the development of their professional self-consciousness.
CHALLENGES FOR EDUCATION CAREER IN THE LITHUANIAN SCHOOLS OF GENERAL EDUCATION: EXPERIENCE OF CAREER SPECIALISTS
Authors: Merfeldaite Odeta , Railiene Asta , Indrasiene Valdone , Jegeleviciene Violeta 
Published: May 2020

The article presents the challenges for the career specialist in provision of career education services in the school of general education. Based on the results of the qualitative research, employing the methods of the focus group discussion, the following conclusions should be made: The main problems faced by the career specialists providing career services in general education schools are the following: heavy workload, lack of cooperation among the career specialists; the schools lack informational and methodological means which would correspond to special needs of the students, of age groups; for improvement of efficiency of the activity of career specialists an information data base containing all available informational, counselling, methodological material designated for the career specialist is required; psychological tests on the subjects of self-awareness and career which could be applied by career specialists on their own, without having psychological education; lack of attractive, corresponding to the needs of the modern labour market and of the students, video material designated for career education; training based on sharing of experience is necessary for qualification improvement
PROMOTION OF YOUTH INVOLVEMENT FOR EARLY SCHOOL LEAVING PREVENTION
Authors: Kanina Inguna 
Published: May 2020

Among the main challenges of contemporary education system are raising the motivation to study, strengthening the bond between the student and the school and prevention of early school leaving. In Latvia as well as in the rest of Europe the percentage of early school leavers still remains high. According to Eurostat data the percentage of students having left school early in Latvia reached 8% in 2018. Moreover the Baltic Social studies stated that altogether 26% of schools have faced the problem of early school leavers. Among the main factors reported as the reason for early school leaving are lack of motivation and risks related to school environment. Using the competency-based learning model new educational goals have been set, as follows, namely methodically moving towards the desired future profession, active involvement in the community, cooperation and developing of the feeling of patriotism. Lielvarde municipality in cooperation with the Ministry of Education and Science has launched a project aimed to gain a better understanding of students’ emotional and mental state, plans for the future as well as raising awareness of possible ways to get support during difficult times. The method used in the research were questionnaires. In the research there were involved students from all schools of Lielvārde district starting with age 13. The main goal of the research is to create a sustainable action plan, in order to gain more involvement from students. The results of research reveal students’ attitude towards studying, their future job options as well as the awareness of possibilities to use support systems in their lives.
21ST CENTURY SKILLS IN THE CONTEXT OF LIFE QUALITY
Authors: Zeide Inga , Odiņa Indra 
Published: May 2020

The article addresses comparative qualitative content analysis as a part of the grounded theory research to explore the relationship between English language proficiency of economically active adults and their quality of life. Using comparative qualitative content analysis of the policy documents in respect of lifelong learning as main data collection method, the authors of the article aim to identify the relationship between the 21st century skills and indicators of life quality by comparing the sources that define the 21st century skills and analysing them in the context of the “8+1” dimensions of life quality offered by the European Union. The following research questions have been proposed: how 21st century skills are defined in the policy documents and how they relate to the quality of human life. The analysis of European Parliament, Council of the European Union, Word Economic Forum and Eurostat policies, models, strategies and their implementation in respect of lifelong learning reveals existing gaps and points at the urgent need in profiling the development of human skills to enhance human well-being and life quality in Europe. Besides, developing new skills and improving existing ones can be a tool for improving the quality of life in the future, whereas the dimensions of life quality can serve as a prerequisite for skills development.
THE EFFICIENCY OF TRANSFERRING ATTENTION-GETTING DEVICES FROM ENGLISH TO LATVIAN: A CASE STUDY IN TRANSLATING NEWSPAPER HEADLINES
Authors: Iļjina Svetlana 
Published: May 2020

The present study aims to explore the effectiveness of translating newspaper headlines from English to Latvian. The present study examines the linguistic devices that are used in order to catch readers’ attention to the headlines in newspapers. The research focuses on the analysis of the techniques that are employed to maintain the linguistic and stylistic equivalence of the utterances in the source and the target languages. The method of discourse analysis is applied in the research. The study concludes that the languages may have similar linguistic techniques to create attractive headlines. Moreover, the contrastive analysis demonstrates the feasibility of rendering the source text attractiveness into the target language. The most difficult decisions to make deal with cultural references that remain attractive only in their original linguistic environment.
POSSIBILITIES OF ACQUIRING COMPETENCIES IN DISEASE MANAGEMENT OF CHILDREN WITH DIABETES MELLITUS
Authors: Čergelytė – Podgrušienė Indre , Gudžinskienė Vida 
Published: May 2020

Diabetes Mellitus is a chronic disease that occurs as a metabolic disorder. Children often have type 1 diabetes, which occurs when pancreas produces very little or no insulin. Type 1 diabetes may negatively affect the normal lifestyle of a child, as well as his/her development, learning results and growth. It is emphasised that it is important for a child to adjust insulin doses based on the consumed food, physical workload and mental strain; therefore, in this case, the child must be aware of diabetes in order to achieve the most optimal health. The subject-matter of research is the opportunities of children with Diabetes Mellitus to acquire competences for the management of their disease. The aim of research is to disclose how children with diabetes acquire competences for the management of their disease and what opportunities they have for such acquisition. The objectives of research are as follows: 1) to discuss what kind of trainings are being provided to children with diabetes in Europe and Lithuania; 2) to disclose which competences help children with diabetes to manage their disease the most based on their experience. Methods of research – theoretical, such as analysis, generalisation and structuring of scientific literature; empirical, such as semi-structured interview used to collect data; and content analysis method used to analyse the obtained research data. 6 children with Diabetes Mellitus participated in this research. The age of the research participants ranged from 10 to 13 years. During the empirical research, it was disclosed that the most important competences of children with diabetes, allowing/enabling them to manage their disease consist of the correct injection of insulin, proper consumption of food and their abilities to manage hypoglycaemia and hyperglycaemia.
ANALYSIS OF COMPETITIVE ACTIVITY HIGH RANKED FIGHTERS OF MIXED MARTIAL ARTS
Authors: Latyshev Sergii , Latyshev Mykola , Mavropulo Olga , Maksimenko Igor , Tkachenko Yuri , Zavodnyy Nikita 
Published: May 2020

Mixed martial arts - a sport, which is a combination of many techniques, schools and direction of combat sports. Nowadays, mixed martial arts are the most popular and spectacular sport of all combat sports. Analysis of competitions performances is an important aspect of training athletes. The quantitative characteristics of competitive activity make it possible to model the training process at different stages of fighters. Aim of the research – to analyze the quantitative characteristics of competitive activity of high ranked fighters. All matches of Mixed martial arts Russian Cup in 2018 were analyzed: 84 preliminary and 8 final fights (for 1 place) in all weight categories. The following quantitative characteristics of the competitive activities of high ranked fighters were analyzed in the study: average fight time; average fight time in the standing and ground positions; distribution of fights by types of victory; activity, defense and reliability performing takedowns for each weight category. Also, a comparative analysis was carried out with the competitive activity characteristics of the top athletes from the Ultimate Fighting Championship rating for each weight group. These data can be used as model when planning the training process of both young and qualified athletes.
SELECTION AND PROFESSIONAL TRAINING OF PERSON PROFILERS IN THE STATE BORDER GUARD OF THE REPUBLIC OF LATVIA
Authors: Madžuls Juris 
Published: May 2020

The effectiveness of profiling depends directly on the professional skills of the employee – profiler. The special attention should be paid to the selection and training of profilers. Profiling is a matter of state, public or company security and it is not acceptable that accidental person enters the profilers’ community. The aim of the paper is to identify the possibilities of improving the profiler candidates selection system and their professional preparedness in line with current socio-economic, political and migration trends in Europe and in the world. The research was done in the State Border Guard College of the Republic of Latvia. For this purpose analysis and evaluation of documents, scientific, pedagogical and psychological literature was performed and conclusions about the necessity of profiler selection and preparedness processes development were summarized.The author brought forward conclusion that with strict selection criteria and future qualification raising possibility - the special position held – profiler, should be established.
ORGANIZATIONAL AND PROFESSIONAL FACTORS OF PERFECTIONISM IN SCIENTIFIC AND PEDAGOGICAL STAFF OF HIGHER SCHOOL
Authors: Grubi Tamara 
Published: May 2020

The attention to the study of perfectionism in high school in Ukraine can be explained with modernization and development of Ukrainian higher education, as an access to the European educational research environment. The interest to the perfectionism in scientific and pedagogical staff of high school can be explained by new requirements for professional activity and these factors demand from a teacher of higher school can be an achievement of new standards, obtaining successfully by focusing on avoiding failures. The study is conducted within the pedagogy field. In this article, the author identifies and analyzes the impact of social-demographic factors (such as age, gender, place of residence), organizational and professional factors (such as job experience, academic degree, post, direction of teaching activity, number of students, level of famousness of higher school, level of social-psychological climate etc.). The four manifestations of perfectionism, which are: - Absence of perfectionism - where normal and pathological perfectionism are represented at a low level. - Perfectionism with negative orientation - consists of the respondents with pathological type of perfectionism.- Ambivalent perfectionism - included the respondents in which the pathological and normal types of perfectionism are equally highly represented. - Perfectionism with positive orientation - consists of the respondents with manifestations of normal type of perfectionism.