bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined abnormal muscle activity and pain-related factors affect disability in patients with chronic low back pain: An association rule analysis
Authors: Shigetoh Hayato , Nishi Yuki , Osumi Michihiro , Morioka Shu 
Published: December 2020

Objectives
In patients with chronic low back pain (CLBP), reduced lumbar flexion-relaxation and reduced variability of muscle activity distribution are reported as abnormal muscle activity. It is not known how abnormal muscle activity and pain-related factors are related to CLBP-based disability. Here, we performed an association rule analysis to investigated how CLBP disability, muscle activity, and pain-related factors in CLBP patients are related.

Methods
Surface electromyographic signals were recorded from over the bilateral lumbar erector spinae muscle with four-channel electrodes from 24 CLBP patients while they performed a trunk flexion re-extension task. We calculated the average value of muscle activities of all channels and then calculated the flexion relaxation ratio (FRR) and the spatial variability of muscle activities. We also assessed the pain-related factors and CLBP disability by a questionnaire method. A clustering association rules analysis was performed to determine the relationships among pain-related factors, the FRR, and the variability of muscle activity distribution.

Results
The association rules of severe CLBP disability were divisible into five classes, including ‘low FRR-related rules.’ The rules of the mild CLBP disability were divisible into four classes, including ‘high FRR-related rules’ and ‘high muscle variability-related rules.’ When we combined pain-related factors with the FRR and muscle variability, the relationship between abnormal FRR/muscle variability and CLBP disability became stronger.

Discussion
Our findings thus highlight the importance of focusing on not only the patients’ pain-related factors but also the abnormal motor control associated with CLBP, which causes CLBP disability.
Pushing Corruption and Money Laundering into Reverse Momentum
Authors: Ekwueme Ejike 
Published: December 2020

In this article, the author emphasizes how corruption and money laundering have caused incalculable economic damage to society. The two problems are intricately linked and very difficult to separate. The board of directors should introduce an enhanced corporate governance mechanism(s) alongside other countermeasures in order to minimize weaknesses in the current system. In exercising their corporate function(s), aside from other committees, the board should focus more on the audit committees. It is very important that the board uses the services of competent non-executive directors (NEDs) on the audit committees. NEDs should monitor the authenticity of audit reports and minimize the occurrence of fictitious financial reports that aid fraud. Efforts at whistle-blowing should be encouraged with rewards by the board for curtailing fraud through such brave conduct. Fictitious and vexatious reports should not go unpunished. The time is ripe for boards to focus on corporate ethics and make sure that they are practised across the entity from ‘the top to the shop floor’. The corporate culture should be seen to nurture the best behaviour in people. This approach has very strong potential to minimize fraudulent and dishonest behaviours that translate into corruption and, by implication, money laundering.
Keywords: corruption; money laundering; board of directors; whistle-blowers; non-executive directors; corporate ethics
China’s New Foreign Investment Law
Authors: Xiaoyang Zhang 
Published: December 2020

China’s legal framework for governing foreign investment has recently been considerably streamlined in comparison to its former self. The newly promulgated Foreign Investment Law of the People’s Republic tends to level the investment playing field in the country so that foreign investors can no longer enjoy significant privileges that have been unavailable to domestic firms and entrepreneurs. Operating a relatively nondiscriminatory mechanism, such as has been introduced, will in practice mean reliance on a negative list approach to confine inflows of overseas capital to specifically identify sensitive sectors. As China has committed its market to opening up on a much grander scale in the foreseeable future, the new foreign investment regime and accompanying ideology may not necessarily deter foreign investors from looking for opportunities in the foreseeable future.
Keywords: China; foreign investment; negative list; market opening-up
The role and function of the e-signature, time stamp, and e-evidence in the context of Turkish commercial law
Authors: Berber Leyla Keser 
Published: December 2020

One of the aims of the Turkish Commercial Code (TCC) is to enable digital companies to promote digital transformation. To achieve this aim, it has brought many novelties to Turkish Law. This paper explains the roles and functions of the e-signature, time stamp and e-evidence in the context of the TCC, and concludes that although the TCC promotes digital companies, further changes to the legal framework are necessary to keep up with the technological advancements.
Index words: Turkish Commercial Code; digital transformation; e-signature; time stamp; e-evidence
The application of forensics examination in crime-related prosecution
Authors: Onwubiko Davidson C. , Eboibi Felix E. 
Published: December 2020

The increased use of the internet and information technology in Nigeria has led to the need to utilize technologies to identify and prosecute perpetrators of crimes. In today’s world, the application of forensics in the investigation and prosecution of crimes is essential. This paper critically examines the effect of the absence of a coordinated standard for the execution and presentation of forensic investigations utilizing electronic evidence in Nigeria. It examines the nature and scope of the various forensic models proposed, while questioning the appropriateness or otherwise of their usefulness in criminal prosecutions. The paper suggests the need for the regulation of forensics practices, the provision of standards, and a universal model for the successful prosecution of crimes in Nigeria.
Index words: Nigeria; forensic examination; digital crime; standardization
Cholesterol-lowering activity of lactic acid bacteria and yeast when used as probiotics in laying quail (Coturnix coturnix Japonica)
Authors: Istiqomah L. , Sakti A. A. , Sofyan A. , Herdian H. , Anggraeni A. S. 
Published: December 2020

This study aimed to evaluate the administration of Lactobacillus plantarum AKK-30 and Saccharomyces cerevisiae B-18 as probiotics in reducing cholesterol of blood, egg, and meat and also the production performance of laying quail (Coturnix coturnix Japonica). A number of 600 birds of the twenty one-day-old quails were distributed in a completely randomized design with 5 treatments and 6 replications (initial BW= 101.35 ± 1.64 g). Treatments were as follows: A = negative control (basal diet without probiotic), B = 1% of L. plantarum AKK-30 (107 cfu/g), C = 1% of S. cerevisiae B-18 (106 cfu/g), D = 1% of a probiotic consortium, E = positive control (commercial probiotic). Parameters observed were blood biochemistry profiles, product quality, and production performance. The results revealed that administration of 1% S. cerevisiae (C) resulted the lowest cholesterol in blood (101.75 mg/dL) and egg (9.44 mg/g) and while administration of 1% L. plantarum(B) increased meat protein and decreased fat content (P<0.05). Level of blood triglycerides, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) were not different among treatments. Probiotic treatments did not affect the growth performance, quail day production (QDP), feed conversion ratio (FCR) and egg uniformity. However, probiotic increased diameter of egg yolk (P<0.05). It was concluded that administration of single probiotic L. plantarum AKK-30 or S. cerevisiae B-18 improves the quality of laying quail products.
An income analysis of beef cattle fattening system and its contribution to the total household income in Central Java Province
Authors: Prasetyo E. , Ekowati T. , Gayatri S. 
Published: December 2020

Beef cattle fattening is raised by farmers in Central Java, but not yet profit oriented. The aims of this research were to analyze the farmer income of beef cattle fattening farm and its contribution to the total household income and to analyze the influence of production costs and farm size toward beef cattle farm income. Survey was used among 150 beef cattle farmers, while multi stage cluster quota sampling was used as sampling method. Income analysis, paired t test, and multiple linear regression were used for data analysis. Research result showed that the farmer’s income from beef cattle farm is IDR 6,736,824.21 per 6.32 month fattening period on an average farm scale was 2.31 heads (equal to IDR 1,065,953.20/month). While, average income of farm households from non-beef cattle farm was IDR 3,516,080.95/month. The contribution of beef cattle farm to household farmer’s income was 30.32%. Based on the paired t test, beef cattle farm income is significantly different and smaller than the income from non-beef cattle farm. Multiple linear regression analysis showed that variable cost and number of beef cattle had a significant effect on beef cattle farm income, while the fixed cost had no significant effect.
Distribution of enterovirus genotypes detected in clinical samples in Hungary, 2010–2018
Authors: Bujaki Erika , Farkas Ágnes , Rigó Zita , Takács Mária 
Published: December 2020

AbstractThis report provides the findings of a retrospective surveillance study on the emergence and circulation of enteroviruses with their associated clinical symptoms over a nine-year period detected at the National Enterovirus Reference Laboratory in Hungary between 2010–2018.Enterovirus (EV) detection and genotyping were performed directly from clinical samples. From 4,080 clinical specimens 25 EV types were identified with a median age of patients of 5 years and 68% of all cases affected children aged 10 years or younger, although infections occurred in all age-groups. In 130 cases neurological symptoms were recorded, in 123 cases the infection presented in skin related signs including hand, foot, and mouth disease (HFMD), herpangina and rash. In 2010 EV-A71 was found to cause the majority of diagnosed EV infections while in 2011 and from 2014–2018, Coxsackievirus (CV)-A6 was identified most often. Echovirus E6 accounted for the most cases in 2012 and Echovirus 30 dominated in 2013. EV-D68 was identified only in 2010 and 2013.Widespread circulation of several EV-A and EV-B viruses with occasional occurrence of EV-C and EV-D was detected. The ability of EVs to cause severe infections in sporadic cases and regular outbreaks highlight the importance of continued monitoring of circulating EV types.
A comparative evaluation of efficacy of epidural dexmedetomidine and fentanyl as adjunct to 0.2% ropivacaine for post-operative analgesia in elective abdominal surgeries
Authors: Gandhi Pushpal , Agrawal Mahendra , Agrawal Bhavika , Behl Simarn 
Published: December 2020

<p class="abstract"><strong>Background:</strong> Epidural analgesia as a central nuraxial technique which involves use of local anesthetics injected into the epidural space to produce a reversible loss of sensation and is the one of the most common regional technique used for lover abdominal and lover limb surgeries epidural analgesia provides excellent pain relief for surgical procedures below the umbilicus. This study compared the efficacy of epidural dexmedetomidine and fentanyl in addition to 0.2% ropivacaine for post-operative analgesia in elective abdominal surgeries.</p><p class="abstract"><strong>Methods:</strong> Total of 150 patients American Society of Anesthesiologists (ASA) I and II between 20-60 years, undergoing major abdominal surgery were included in this study. The patients divided in three groups of 50 patients each. First group R (ropivaciain 0.2% 9 ml with 1ml normal saline) second group RF (ropivacain 0.2% 9 ml with fentanyl 1 ml) and third group RD (ropivaciain 0.2% 9 ml with dexmedetomidine 1 μ/kg).</p><p class="abstract"><strong>Results:</strong> There is no significant difference in age, weight, sex, and ASA grade in all three groups.</p><p class="abstract">Hypotension was observed in 4 (8%) patients of R group, 2 (4%) in RD group and 4 (8%) in RF group. The shivering was present in 2 (4%) R group and 2 (4%) in RD group. Nausea, vomiting was present in R group 2 (4%) and 2 (4%) in RF group. There was no significant difference between the three groups with respect to hemodynamic parameters like heart rate, systolic and diastolic blood pressure and respiratory rate.</p><p class="abstract"><strong>Conclusions: </strong>Dexmedetomidine is a better adjuvant to ropivacaine through epidural route when compared to fentanyl for providing early onset prolonged post-operative analgesia, sedation and stable hemodynamic parameters in intra-abdominal surgeries.</p>
Reformulation of Allah’s Ownership on Waqf (Theoretical Analysis Toward Syāfi’i School)
Authors: Ghozalie Fathurrohman , Muallim Amir , Tono Sidik 
Published: December 2020

Abstract: Waqf is the act of someone who holds some of his property and gives the benefits of the property. Waqf in Indonesia generally follows the opinion of the Shafi'i school that said the waqf property belongs to Allah. This opinion is not right in Islamic ownership perspective which said that every property must be owned by humans unless it is specified by the Shari'a. This research is normative Islamic law research with the theory of ownership in Islam and the maslaha theory. This research found that Allah's ownership of waqf property needs to be reformulated to equate it to the theory of ownership in Islam and to be useful for human life. This reformulation is by establishing the legal entity as the owner of the waqf property because the legal entity can represent God's ownership. Keywords: Reformulation; Ownership; Waqf; Benefit Abstrak: Wakaf adalah perbuatan seseorang yang menahan sebagian hartanya dan mensedekahkan manfaat harta tersebut. Perwakafan di Indonesia pada umumnya mengikuti pendapat mazhab Syafi’i yang mengatakan bahwa harta wakaf menjadi milik Allah. Paham tersebut tidak sesuai dengan ketentuan tentang kepemilikan dalam Islam yang menetapkan bahwa setiap benda yang ada di muka bumi harus dimiliki oleh manusia kecuali ditentukan lain oleh syariat. Penelitian ini adalah penelitian hukum Islam normatif dengan pendekatan teori kepemilikan dalam Islam dan teori kemaslahatan. Penelitian ini menemukan bahwa kepemilikan Allah atas harta wakaf perlu direformulasi supaya sesuai dengan ketentuan tentang kepemilikan dalam Islam dan supaya bermaslahat bagi kehidupan manusia. Reformulasi tersebut ialah dengan menetapkan badan hukum sebagai pemilik harta wakaf karena badan hukum dapat merepresentasikan kepemilikan Allah. Kata kunci: Reformulasi, Kepemilikan, Harta wakaf, Kemaslahatan
Joint lesions in inflammatory bowel diseases: the analysis of the Moscow regional patient registry and a clinical case
Authors: Taratina O. V. , Belousova E. A. 
Published: December 2020

Rationale: Extraintestinal manifestations (EIM) of an inflammatory bowel disease (IBD) are a sign of its more severe course. Joint lesions are most common among IBD EIM.Aim: To evaluate the prevalence and types of joint lesions in the population of IBD patients of the Moscow region.Materials and methods: We performed a retrospective analysis of medical files of the patients who were admitted to the Moscow Region Inflammatory Bowel Disease Center (MONIKI) for examination and treatment from August 1, 2019, to March 1, 2020. The study included 70 patients with confirmed diagnoses of IBD and confirmed or suspected involvement of the joints.Results: Thirty six of 70 patients with IBD and EIM (51.43%) had been diagnosed with Crohn's disease (CD), and 34 (48.57%) with ulcerative colitis (UC). The CD group included more men (n=21, 58.33%), whereas their proportion in the UC group was 47.02% (n=16). The mean age at CD diagnosis in the UC and CD groups was comparable: 38.3±13.7 years in men with CD and 40.5±12.8 years in men with UC, 37.7±11.1 years in women with CD and 35.7±14.0 in women with UC. The most prevalent among all IBD patients were X-ray negative peripheral arthralgias. Among joint lesions confirmed by radiological diagnostics, sacroileitis was most prevalent both in all IBD patients (24.3%), as well as in the UC group (17.6%), whereas in the CD patients its frequency was the same as that of ankylosing spondyloarthritis (AS) (30.6% of the cases). AS ranked second in the prevalence of joint lesions in the UC group (8.8%) and all IBD (20%). Psoriatic arthritis was diagnosed only in the CD patients (2 / 36). We describe a clinical case of CD with AS, complicated with psoriatic rash, treated with a monoclonal antibody to tumor necrosis factor alfa (anti-TNF-α).Conclusion: Peripheral arthropathias were most prevalent among all joint lesions in the group studied. EIM mirror a more aggressive phenotype of the disease and higher glucocorticosteroids requirements. Administration of anti-TNF-α agents allows for the control of both intestinal IBD manifestations and of the joint syndrome. However, drug-associated skin adverse event can occur during treatment with this drug class. In such a case, it is possible to switch the biological therapy to another class of drugs that we have demonstrated with the given clinical example.
The effects of contextual factors on Universitario lecturer's performance
Authors: Rosales-Asensio Enrique 
Published: December 2020

The purpose of this paper is to identify the set of conditions of the instructional context that lecturers take into account in the design of university teaching. The main results show the existence of six relevant instructional conditions, which we have named: a) Content, subject, lecturers and students; b) Teaching innovation and educational resources; c) Course design; d) Attitude of students; e) Characteristics of students and f) Lecturer-subject relationship. We conclude by evaluating the contributions made by the paper to the available knowledge of the subject and pointing out some challenges for future research.
Keywords: Basic knowledge for teaching, conditions of teaching, instructional design
Keywords: Conditions of teaching, basic knowledge for teaching, instructional design.
Risk factors for rapid axial length elongation with low concentration atropine for myopia control
Authors: Fu Aicun , Stapleton Fiona , Wei Li , Wang Weiqun , Zhao Bingxin , Watt Kathleen , Yu Shiao , Cui Can , Lyu Yong 
Published: December 2020

Abstract
Three hundred and twenty-eight myopic children, randomized to use either 0.01% (N=166) or 0.02% (N=162) atropine were enrolled in this study. Gender, age, body mass index(BMI), parental myopia status, atropine concentration used, pupil diameter, amplitude of accommodation, spherical equivalent refractive error (SER), anterior chamber depth (ACD) and axial length (AL) were collected at baseline and 1 year after using atropine. Rapid AL elongation was defined as >0.36 mm growth per year. Univariate analyses showed that children with rapid AL elongation tend to be younger, have a smaller BMI, use of 0.01% atropine, narrow ACD, lower SER, shorter AL, smaller change in pupil diameter between 1 year and baseline (all P < 0.05). Multivariate regression analyses confirmed that rapid AL elongation was associated with children that were younger at baseline (P < 0.0001), use of 0.01% atropine (P = 0.04), a shorter baseline AL (P = 0.03) and a smaller change in pupil diameter between 1 year and baseline (P = 0.04). Younger children with shorter AL at baseline, less change in their pupil diameter with atropine treatment and using the lower of the two atropine concentrations may undergo rapid AL elongation over a 12 months myopia control treatment period.
Production and characterization of semi-quinolone antibiotic produced by Streptomyces griseorubens
Authors: Abdulkhair Waleed , Alghuthaymi Mousa 
Published: December 2020

Abstract
This work is an attempt to overcome antimicrobial resistance problem which dispersed worldwide inparticular developing countries due to misuse of antibiotics. Actinobacteria were isolated and screenedagainst selected resistant Gram-negative bacteria to detect the powerful antibacterial activity.Identification of the most potent actinobacterial isolate has been carried out using classical and geneticalmethods. Antibacterial compound has been extracted, purified and characterized using accurate and morespecific techniques and instruments. Among forty actinobacterial isolates, only twenty-two isolates couldinhibit the growth of Gram-negative bacteria. The most potent isolate Eg-7 was identified as S.griseorubens, which has a typical 16S rRNA gene. The antibacterial compound was extracted using ethylacetate, and separated by High Performance Liquid Chromatography using methanol and water as amobile phase. Five active peaks were displayed and retained in the range 40 – 45 min, but the last threepeaks were retained at 41.90, 43.43, and 44.54 min, respectively. The crude extract was analyzed byliquid chromatography mass spectrum, where the active peak was displayed at 721.325 m/z. Theantibacterial compound was purified using flash column chromatography and gel filtration columnchromatography. The active fraction was analyzed by Infra-Red spectrum, where a broad absorption at3338 cm-1 was displayed. Molecular formula of an antibacterial compound was determined by massspectrum as C35H26N6O4. Nuclear magnetic resonance analysis was carried out for an antibacterialcompound. These results suggest that a new antibacterial compound that similar quinolone could beproduced by S. griseorubens and exhibited a higher activity against Gram-negative bacteria.
In Ovo and Oral Administration of Probiotic Lactobacilli Modulate Cell- and Antibody-Mediated Immune Responses in Newly Hatched Chicks
Authors: Alizadeh Mohammadali , Bavananthasivam Jegarubee , Shojadoost Bahram , Astill Jake , Abdelaziz Khaled , Alqazlan Nadiyah , Doost Janan Shoja , Sharif Shayan 
Published: December 2020

Abstract
There is some evidence that lactobacilli can strengthen immune system of chickens. This study evaluated the effects of in ovo and oral administration of a lactobacilli cocktail on cytokine gene expression, antibody-mediated immune response, and spleen cellularity in chickens. Lactobacilli were administered either in ovo at embryonic day 18, orally to hatched chicks at days 1, 7, 14, 21, and 28 post-hatches, or by both treatments combined. On days 5 and 10 post-hatch, spleen and bursa of Fabricius were collected for gene expression and cell composition analysis. On days 14 and 21 post-hatch, birds were injected with sheep red blood cells (SRBC) and keyhole limpet hemocyanin (KLH), and sera were collected on days 7, 14, and 21 post-primary immunization. Birds that received lactobacilli (107 CFU) via in ovo followed by weekly oral administration showed a greater immune response by enhancing antibody response, increasing the percentage of CD4+ and CD4+CD25+ T cells in the spleen, and upregulating the expression of the expression of interferon (IFN)-α, IFN-β, interleukin (IL)-12, and IL-13 in the spleen and expression of IFN-γ, IL-2, IL-6, IL-8, IL-12, and IL-18 in bursa. These findings suggest that pre-and post-hatch administration of lactobacilli modulate immune response in newly hatched chickens.