bluuebunny/crossref_metadata_2025_split huggingface dataset:
Next Generation of LFD Testing – Smartphone-Based Mycotoxin Analysis with RIDA®SMART APP
Authors: Pumpa Kai , Lacorn Markus , Mättner Michael , Steinmann David , Wolf Jasmin 
Published: September 2020

Abstract

Background
Grain mills, feed mills, ethanol plants, flour producers, but also mobile laboratory services need simple and reliable possibilities to analyze grain for mycotoxins during harvest in the field.

Objective
The RIDA®SMART APP is a smartphone application, which was developed together with a Lateral Flow Device as a quantitative and fast on-site/on-field tool for mycotoxin analyses.

Method
It is a small and light device with its own power supply, very versatile, flexible and easy to use. For quantification, a lot specific calibation curve is uploaded to the RIDA®SMART APP via a QR code from the certificate of analysis. The software application in combination with a compatible smartphone, analyzes the LFD strip via a picture taken with a smartphone and quantifies the mycotoxin contamination within 4 second. Due to the possibility to use mobile networks or WIFI, there are no difficulties in the organization of the collected results. Currently, nine different android-based smartphones from various manufacturers are compatible with the RIDA®SMART APP.

Results
In combination with one of the compatible smartphones, the RIDA®SMART APP is able to generate results with a coefficient of variation CV ≤ 13%, even at highly varying lighting conditions. The recovery of certified reference corn samples, previously analyzed with HPLC or LC-MS/MS, shows a mean value between 91% - 119%.

Conclusion
The RIDA®SMART APP is highly suitable for an inexpensive, quick and accurate quantitative measurement of mycotoxins in agricultural products (e.g. aflatoxins in corn).

Highlights
To our best knowledge, the RIDA®SMART APP is the only smartphone-based method for quantitative mycotoxin analysis worldwide combined with a broader measuring range as most usual lateral flow analyzers.
Multiorgan Metabolomics and Lipidomics Provide New Insights Into Fat Infiltration in the Liver, Muscle Wasting, and Liver–Muscle Crosstalk Following Burn Injury
Authors: Mert Safak , Bulutoglu Beyza , Chu Christopher , Dylewski Maggie , Lin Florence M , Yu Yong-Ming , Yarmush Martin L , Sheridan Robert L , Uygun Korkut 
Published: September 2020

AbstractBurn injury mediated hypermetabolic syndrome leads to increased mortality among severe burn victims, due to liver failure and muscle wasting. Metabolic changes may persist up to 2 years following the injury. Thus, understanding the underlying mechanisms of the pathology is crucially important to develop appropriate therapeutic approaches. We present detailed metabolomic and lipidomic analyses of the liver and muscle tissues in a rat model with a 30% body surface area burn injury located at the dorsal skin. Three hundred and thirty-eight of 1587 detected metabolites and lipids in the liver and 119 of 1504 in the muscle tissue exhibited statistically significant alterations. We observed excessive accumulation of triacylglycerols, decreased levels of S-adenosylmethionine, increased levels of glutamine and xenobiotics in the liver tissue. Additionally, the levels of gluconeogenesis, glycolysis, and tricarboxylic acid cycle metabolites are generally decreased in the liver. On the other hand, burn injury muscle tissue exhibits increased levels of acyl-carnitines, alpha-hydroxyisovalerate, ophthalmate, alpha-hydroxybutyrate, and decreased levels of reduced glutathione. The results of this preliminary study provide compelling observations that liver and muscle tissues undergo distinctly different changes during hypermetabolism, possibly reflecting liver–muscle crosstalk. The liver and muscle tissues might be exacerbating each other’s metabolic pathologies, via excessive utilization of certain metabolites produced by each other.
Spatial Distribution of Whitefly Species (Hemiptera: Aleyrodidae) and Identification of Secondary Bacterial Endosymbionts in Tomato Fields in Costa Rica
Authors: Can-Vargas Xareni , Barboza Natalia , Fuchs Eric J , Hernández Eduardo J 
Published: September 2020

AbstractIn Costa Rica, tomato (Solanum lycopersicum Linnaeus) Linnaeus (Solanales: Solanaceae) is one of the crops most severely affected by the whiteflies (Hemiptera: Aleyrodidae) Trialeurodes vaporariorum (Westwood) and the Bemisia tabaci (Gennadius) species complex. The objective of this study was to monitor the spatial distribution and diversity of these species and to detect the presence of secondary bacterial endosymbionts in individuals collected in areas of intensive tomato production. In total, 628 whitefly individuals were identified to the species level using restriction analysis (PCR-RFLP) of a fragment of the mitochondrial cytochrome C oxidase I gene (mtCOI). Trialeurodes vaporariorum was the predominant species, followed by B. tabaci Mediterranean (MED). Bemisia tabaci New World (NW) and B. tabaci Middle East-Asia Minor 1 (MEAM1) were present in lower numbers. The mtCOI fragment was sequenced for 89 individuals and a single haplotype was found for each whitefly species. Using molecular markers, the 628 individuals were analyzed for the presence of four endosymbionts. Arsenophonus Gherna et al. (Enterobacterales: Morganellaceae) was most frequently associated with T. vaporariorum, whereas Wolbachia Hertig (Rickettsiales: Anaplasmataceae) and Rickettsia da Rocha-Lima (Rickettsiales: Rickettsiaceae) were associated with B. tabaci MED. This study confirmed that B. tabaci NW has not been completely displaced by the invasive species B. tabaci MED and B. tabaci MEAM1 present in the country. An association was found between whitefly species present in tomato and certain secondary endosymbionts, elevation was the most likely environmental factor to affect their frequency.
Rabbit Bot Fly Furuncular, Tracheopulmonary, and Human Bot Fly Infestations in Connecticut (Oestridae: Cuterebrinae)
Authors: Stafford Kirby C , Ridge Gale E , Molaei Goudarz , Zarb Christine , Bevilacqua Paula 
Published: September 2020

Abstract
Endemic and tropical human bot infestations are relatively uncommon or unreported in the United States. We report two cases in Connecticut: an unusual furuncular and respiratory myiasis by the rabbit bot Cuterebra buccata (Fab.) (Diptera: Oestridae) in a 74-yr-old male and a case of human bot fly, Dermatobia hominis (L.) (Diptera: Oestridae), myiasis in a 4-yr-old female with a tropical travel history with her family. Identification of C. buccata was based morphologically, in part, on spinal armature and further corroborated by DNA sequencing of the mitochondrial COI gene and comparison to the National Center for Biotechnology Information GenBank DNA sequence database. The resulting annotated sequence data were deposited into the National Center for Biotechnology Information GenBank. The unique medical aspects, and limitations and specifics on bot fly larval habits and identification are discussed.
Prostate Cancer Radiotherapy: Increased Biochemical Control and Late Toxicity in Men With Medication Allergies
Authors: Turchan William Tyler , Gutiontov Stanley I , Spiotto Michael T , Liauw Stanley L 
Published: September 2020

AbstractBackgroundGiven similarities in the mediators of medication allergy (MA) and tissue response to radiotherapy, we assessed whether outcomes following prostate radiotherapy differ in patients with MAs.MethodsA total 587 men with known MA history and nonmetastatic prostate cancer underwent radiotherapy from 1989 to 2006. Clinicopathologic and treatment variables were analyzed for association with freedom from biochemical failure (FFBF) and late treatment–related, physician-defined Radiation Therapy Oncology Group gastrointestinal (GI) and genitourinary (GU) toxicity. Covariates identified on univariate analysis for toxicity and disease control were examined on multivariable analysis. All statistical tests were 2-sided, and a P less than .05 was considered statistically significant.ResultsA total of 155 of 587 men (26.4%) had 1 or more MAs, most commonly to penicillin (n = 71), sulfa (n = 35), and aspirin or nonsteroidal antiinflammatory drugs (n = 28). On univariate analysis, men with MAs had superior 10-y FFBF (71.5% vs 63.5%, P = .02) and higher incidence of late GI grade 2 or higher (G2+; 20.6% vs 13.2%, P = .04) and grade 3 or higher (G3+; 7.5% vs 3.9%, P = .08) as well as late GU G2+ (42.5% vs 33.2%, P = .04) and G3+ (7.5% vs 3.0%, P = .02) toxicity than men without MAs. On multivariable analysis, MA history remained a statistically significant predictor of FFBF (hazard ratio [HR] = 0.64, 95% confidence interval [CI] = 0.43 to 0.93, P = .02), late G2+ GI (HR = 1.76, 95% CI = 1.06 to 2.90, P=.03), and G3+ GU (HR = 2.69, 95% CI = 1.16 to 6.27, P = .02) toxicity after controlling for corresponding covariates in each model.ConclusionsMen with MAs had improved FFBF and increased treatment-related toxicity following radiotherapy for prostate cancer. MA history could be a relevant consideration in the management of men with localized prostate cancer.
Comparison of Parental Report of Influenza Vaccination to Documented Records in Children Hospitalized With Acute Respiratory Illness, 2015–2016
Authors: Ogokeh Constance E , Campbell Angela P , Feldstein Leora R , Weinberg Geoffrey A , Staat Mary A , McNeal Monica M , Selvarangan Rangaraj , Halasa Natasha B , Englund Janet A , Boom Julie A , Azimi Parvin H , Szilagyi Peter G , Harrison Christopher J , Williams John V , Klein Eileen J , Stewart Laura S , Sahni Leila C , Singer Monica N , Lively Joana Y , Payne Daniel C , Patel Manish ,   New Vaccine Surveillance Network
Published: September 2020

Abstract

Background
Parent-reported influenza vaccination history may be valuable clinically and in influenza vaccine effectiveness (VE) studies. Few studies have assessed the validity of parental report among hospitalized children.

Methods
Parents of 2597 hospitalized children 6 months–17 years old were interviewed from November 1, 2015 to June 30, 2016, regarding their child’s sociodemographic and influenza vaccination history. Parent-reported 2015–2016 influenza vaccination history was compared with documented vaccination records (considered the gold standard for analysis) obtained from medical records, immunization information systems, and providers. Multivariable logistic regression analyses were conducted to determine potential factors associated with discordance between the 2 sources of vaccination history. Using a test-negative design, we estimated VE using vaccination history obtained through parental report and documented records.

Results
According to parental report, 1718 (66%) children received the 2015–2016 influenza vaccine, and of those, 1432 (83%) had documentation of vaccine receipt. Percent agreement was 87%, with a sensitivity of 96% (95% confidence interval [CI], 95%–97%) and a specificity of 74% (95% CI, 72%–77%). In the multivariable logistic regression, study site and child’s age 5–8 years were significant predictors of discordance. Adjusted VE among children who received ≥1 dose of the 2015–2016 influenza vaccine per parental report was 61% (95% CI, 43%–74%), whereas VE using documented records was 55% (95% CI, 33%–69%).

Conclusions
Parental report of influenza vaccination was sensitive but not as specific compared with documented records. However, VE against influenza-associated hospitalizations using either source of vaccination history did not differ substantially. Parental report is valuable for timely influenza VE studies.
There’s an App for That: Context, Assumptions, Possibilities and Potential Pitfalls In the Use of Digital Technologies To Address Refugee Mental Health
Authors: Goodman Ruth , Tip Linda , Cavanagh Kate 
Published: September 2020

Abstract
The number of refugees is increasing (UNHCR, 2019). The experiences of refugees are linked to impaired mental health yet, this population faces barriers to accessing mental health support (Shannon et al., 2016). Digital mental health interventions are increasingly recognised as an avenue for overcoming these barriers (WHO, 2017). The present paper begins by introducing the area of digital approaches to mental health and developments in this area targeted at refugee populations specifically. We then take a step back to look at the wider picture of refugee mental health and technology. Drawing on Toyama’s Law of Amplification (2011; 2015) - that successful technical interventions amplify the intent and the capacity of the people involved - we discuss the importance of context, exploring the assumptions, possibilities and potential pitfalls in the use of digital technologies for addressing refugee mental health. We conclude that by collaborating with refugee populations, placing them at the centre of the design process for digital mental health interventions, we stand the greatest chance of creating the most useful tools.
An abstract form of the first epsilon theorem
Authors: Baaz Matthias , Leitsch Alexander , Lolic Anela 
Published: September 2020

Abstract
We present a new method of computing Herbrand disjunctions. The up-to-date most direct approach to calculate Herbrand disjunctions is based on Hilbert’s epsilon formalism (which is in fact also the oldest framework for proof theory). The algorithm to calculate Herbrand disjunctions is an integral part of the proof of the extended first epsilon theorem. This paper introduces a more abstract form of epsilon proofs, the function variable proofs. This leads to a computational improved version of the extended first epsilon theorem, which allows a nonelementary speed up of the computation of Herbrand disjunctions. As an application, sequent calculus proofs are translated into function variable proofs and a variant of the axiom of global choice is shown to be removable from proofs in Neumann–Bernays–Gödel set theory.
Perceiving the Mosaic: Form in the Mashups of DJ Earworm
Authors: Yunek Jeffrey Scott , Wadsworth Benjamin K , Needle Simon 
Published: September 2020

AbstractThe formal analysis of mashups is generally overlooked because their structures are assumed to be derived from one or more of their component tracks. This article explores the generation of original formal structures in one of the most well-known and complex mashup artists, DJ Earworm. We show that the form of his mashups can neither be derived from a singular work nor be analyzed by their thematic or harmonic construction. Instead, verse–chorus forms are revealed by correlating mashup sections to the formal origins of their borrowed material, which is based on the composer’s writings and interviews, a history of formal correlation in the mashup genre, and multiple analyses.
Supply Chain Financing
Authors: Rogers Dale S. , Leuschner Rudolf , Choi Thomas Y. 
Published: September 2020

Abstract
Supply chain management has been focused on how to source, make, and deliver products throughout the world. This chapter proposes the addition of one more function to that list—to fund. As a result of technology supporting financial firms, such as banks and financial technology firms, the supply chain has become the least expensive source of capital available to a firm. Corporate executives increasingly rely on the supply chain as a source of capital. A typical supply chain has three major flows: product, information, and finances. These three flows can vary in importance depending on the environment and supply chain structure. Most of the supply chain management literature focuses on products and information flows and pays minimal attention to the financial side of supply chain management. This chapter views supply chain financing as a bigger concept than the concept commonly known as supply chain finance. Supply chain financing focuses on how to use the supply chain to fund the organization and how to use the organization to fund the supply chain. The goal of supply chain financing is to ensure liquidity within supply chains by helping the buyer and supplier organizations conserve their own capital by injecting liquidity from sources that previously were not known or available.
Supply Chain Management and Gender
Authors: Paiva Ely , Tonelli Maria Jose , Miguel Priscila , Biazzin Cristiane 
Published: September 2020

Abstract
This chapter describes how the gender relations that are present in the globalization process do not reflect the neutral practice presented in the literature, but instead represent a gendered phenomenon that promotes new arrangements of inequalities that impact supply chain management. For decades, gender inequity in supply chains was a “hidden” problem in several sectors, but in the early twenty-first century it is an overt challenge for supply chain management. Gender inequity exists in supply chains when there is low participation of women-owned businesses in supply, a clear wage inequity along the supply chain, and the identification of modern slavery or forced labor related to gender in any tier of a supply chain. A future agenda for gender issues in supply chains should address a range of issues, from the increase in the number of women-owned suppliers and its impacts, to equalization of income among genders throughout supply chains, to complete eradication of modern slavery in local and global supply chains.
Neuronal Excitability in Memory Allocation: Mechanisms and Consequences
Authors: Jacob Alexander D. , Mocle Andrew J. , Frankland Paul W. , Josselyn Sheena A. 
Published: September 2020

Abstract
Throughout the brain, sparse ensembles of neurons, termed “engrams,” are responsible for representing events. Engrams are composed of neurons active at the time of an event, and recent research has revealed how these active neurons compete to gain inclusion into a subsequently formed engram. This competitive selection mechanism, called “memory allocation,” is the process by which individual neurons become components of the engram. Memory allocation is crucially influenced by neuronal excitability, with more highly excitable neurons outcompeting their neighbors for inclusion into the engram. The dynamics of this excitability-dependent memory allocation process have important consequences for the function of the memory circuit, including effects on memory generalization and linking of events experienced closely in time. Memory allocation arises from cellular mechanisms of excitability, governs circuit-level dynamics of the engram, and has higher-order consequences for memory system function.
The Career Development Profession: Professionalisation, Professionalism, and Professional Identity
Authors: Gough John , Neary Siobhan 
Published: September 2020

Abstract
This chapter examines the professionalisation of career development provision in countries across the world. ‘Professionalisation’ and ‘professionalism’ are explored through several concepts, including social closure, the professional project, and the regulatory bargain. The chapter argues that professionalism is a useful and important concept for the career development field but recognises the challenges that the field has had in achieving professional status. It recognises some of the critiques that exist of professionalism and explores how these relate to careers professionals. It then argues that increasing professionalism within the field needs to be understood as an ongoing process that has to be conducted on the personal, organizational, and professional level. The chapter concludes by outlining some key strategies that the field can use to advance the cause of professionalism in the future.
Transgender Language, Transgender Moment: Toward a Trans Linguistics
Authors: Zimman Lal 
Published: September 2020

Abstract
This chapter sketches out trans linguistics as an emerging framework for research on language in populations defined by their deviation from gender norms. Although queer linguistics has always been concerned with both sexual and gender (non)normativity, some early queer linguistic analyses of transgender or otherwise gender-variant populations were limited by the absence of openly trans scholars and distinctively trans analytic perspectives. Trans linguistics, by contrast, centers trans practices and subjectivities not as rare exceptions, but as central to any understanding of gender. Three domains of language are discussed here, including grammatical gender, gender difference in the voice, and gender in discourse. In each case, trans linguistic research offers new perspectives on gendered power, the nature of categories, the significance of embodiment, and the linguistic navigation of persistent dehumanization. Crucially, trans linguistics is committed not only to trans analytic lenses, but also to social and linguistic justice for gender non-normative communities.
Groundbreaking Contributions to Downburst Monitoring, Modeling, and Detection
Authors: Burlando Massimiliano , Romanic Djordje 
Published: September 2020

Abstract
Severe winds produced by thunderstorm outflows cause damage to structures and properties worldwide. Due to their high frequency of occurrence, these winds can be considered one of the most high-risk phenomena in the plethora of the dangerous manifestations of the weather in the troposphere. Through the analysis of experimental data that initiated with visual observations and followed with quantitative measurements, the downburst phenomenon was first discovered and measured in the second half of the last century. Since then, the physical processes responsible for downburst formation have been identified thanks to the advances in observing systems, numerical modeling techniques, as well as smaller scale physical experiments carried out under well-controlled and confined conditions. The purpose of this chapter is to summarize what has been learned about kinematics, dynamics, and thermodynamics of downbursts and unveil the physics behind this phenomenon, running through the most relevant discoveries over the last half century in this research field.
Characteristics of Downslope Wind Storms in the View of the Typical Atmospheric Boundary Layer
Authors: Kozmar Hrvoje , Grisogono Branko 
Published: September 2020

Abstract
There is a clear need to learn more about the exact characteristics of downslope wind storms in order to accurately address relevant topics in environmental aerodynamics and wind engineering. In particular, the characteristics of the atmospheric boundary layer are well known and provided in international standards and textbooks; however, further work is required to elucidate characteristics of downslope wind storms and make these characteristics available in a form suitable for engineering applications. While downslope wind storms have been successfully addressed in the meteorology, climatology, and geophysics communities, the focus of those groups is quite different from the focus in wind engineering; that is, the existing data on characteristics of downslope wind storms are of marginal relevance for engineering applications. It is therefore the scope of this chapter to provide a critical review of the state of the art on characteristics of those local and unique winds in comparison with the typical atmospheric boundary layer. It is expected that this work will encourage a more detailed codification of those winds. Another important goal is to enhance an interdisciplinary collaboration among the meteorology, geophysics, and engineering communities because it is shown in this chapter that the current wind engineering standards do not entirely keep up with the atmospheric physics of downslope wind storms.