bluuebunny/crossref_metadata_2025_split huggingface dataset:
A POLÍTICA DE CONCESSÃO EM FLORESTAS PÚBLICAS NO ESTADO DO PARÁ: O CASO DA UNIDADE DE MANEJO FLORESTAL (UMF) III DA GLEBA ESTADUAL MAMURU ARAPIUNS
Authors: Pereira Luciana Di Paula , Vasconcellos Sobrinho Mario , Flores Maria do Socorro Almeida 
Published: December 2019

A modalidade de uso dos recursos florestais denominada concessão florestal é a forma de gestão em que o Estado delega a um concessionário o direito de gerenciar a exploração de uma área de floresta de domínio público. O objetivo deste artigo é analisar a efetividade desse modelo de gestão a partir da análise de um caso específico de concessão florestal, particularmente o caso da Unidade de Manejo Florestal III (UMF III) da Gleba Estadual do Mamuru Arapiuns, localizada entre os municípios de Santarém, Juruti e Aveiro, no estado do Pará. A análise é realizada a partir dos dados públicos disponíveis em órgãos ambientais do estado e da federação. Toma-se como referência para análise da efetividade os critérios estabelecidos pelo próprio edital público de concessão florestal da UMF III de Gleba Estadual do Mamuru Arapiuns reorganizados nas dimensões econômico-sociais, ambientais e institucionais. O artigo demonstra que a concessão florestal é eficiente enquanto política pública e eficaz enquanto ferramenta de gestão, porém, não há clareza quanto a efetividade do uso dos recursos para o desenvolvimento das comunidades locais. Para tanto, este artigo usou como parâmetro de referência as disposições da Lei Federal Nº 11.284, a Lei de Gestão de Florestas Públicas (LGFP), aprovada em 2006, apoiado por Sano e Montenegro Filho (2013), que permite realizar avaliação preliminar acerca das definições de eficiência, eficácia e efetividade no que diz respeito a legislação em questão. PALAVRAS-CHAVE: Concessão Florestal, Recurso Florestal; Política Pública, Comunidades Locais, Sustentabilidade.
Arthroscopic Treatment of Collapsed Subchondral Fatigue Fracture in the Femoral Head of a Young Military Recruit at a 5-Year Follow-Up
Authors: Kim Chul-Ho , Moon Jun-Ki , Yoon Jae Youn , Yoon Pil Whan 
Published: December 2019

Case:
A 20-year-old military recruit presented with pain in his left hip. He was referred by the military hospital for osteonecrosis of the femoral head in both hip joints. Plain radiographs and magnetic resonance imaging showed a marked collapse in the left femoral head; however, the patient was diagnosed as having subchondral fatigue fractures of the femoral head (SFFFH) after a thorough review of previous sequential images. Arthroscopic debridement and labral repair were performed. At 3 years after surgery, the patient was symptom-free and second-look hip arthroscopy revealed the articular defect filling with fibrocartilage on the femoral head.

Conclusion:
In a young patient, hip arthroscopy can be a successful joint preserving treatment option even for collapsed SFFFH.
Borehole-image-log characterization of deltaic deposits from a behind-outcrop well: Opportunities and limitations
Authors: Wolpert Philipp J. , Poppelreiter Michael C. 
Published: December 2019

ABSTRACTBorehole imaging (BHI) is a fast and precise method for collecting subsurface data. Rock calibration may reduce uncertainties inherent in interpretations of BHI logs. However, only few data sets are published that link borehole image facies to core and outcrop facies of deltaic successions. The objective of this paper is to compare and contrast sedimentologic features as seen in BHI, core, and outcrop, using a structured and hierarchical workflow. The research will provide a global framework for the interpretation of borehole images in similar environments.A shallow, behind outcrop, research well (“Mondot-1”) drilled in NW Spain, penetrated a 185.50 m (TVD) thick section of the deltaic Sobrarbe Formation. A Formation MicroImager (FMI) borehole image log and a comprehensive well log suite was acquired in the fully cored well. The Eocene Sobrarbe Formation consists mostly of siliciclastic and some carbonate facies. Rapid vertical and lateral facies changes over a few tens of meters are observed in outcrops of the Sobrarbe Formation. The cored part of the formation is composed of argillaceous sandstone and carbonate with few diagnostic sedimentary features that can be used to constrain a conceptual depositional model. To provide a sedimentologically sound interpretation of this FMI log, we focused on layers showing diagnostic sedimentary features. Subsequently, facies associations and stratigraphic sequences were interpreted. Each facies association contained sedimentologic tie points that anchored the interpretation with diagnostic features such as slumps.This paper suggests interpreting BHI false-color images of deltaic successions using conceptual geologic constraints such as 1) depositional tie points, 2) genetically related facies associations, and 3) a hierarchical stratigraphic framework, to establish meaningful conceptual depositional models.
Comparative transcriptomic and metabolic analysis of wild and domesticated wheat genotypes reveals differences in chemical and physical defense responses against aphids
Authors: Batyrshina Zhaniya S , Yaakov Beery , Shavit Reut , Singh Anuradha , Tzin Vered 
Published: December 2019

Abstract

Background Young wheat plants are continuously exposed to herbivorous insect attack. To reduce insect damage and maintain their growth, plants evolved different defense mechanisms, including the biosynthesis of deterrent compounds named benzoxazinoids, and/or trichome formation that provides physical barriers. It is unclear whether both of these mechanisms are equally critical in providing an efficient defense for wheat seedlings against aphids—an economically costly pest in cereal production. Results: In this study, we compared the transcriptome, metabolome, benzoxazinoids, and trichome density of three selected wheat genotypes, with a focus on differences related to defense mechanisms. We chose diverse wheat genotypes: two tetraploid wheat genotypes, domesticated durum ‘Svevo’ and wild emmer ‘Zavitan,’ and one hexaploid bread wheat, ‘Chinese Spring.’ The full transcriptomic analysis revealed a major difference between the three genotypes, while the clustering of significantly different genes suggested a higher similarity between the two domesticated wheats than between either and the wild wheat. A pathway enrichment analysis indicated that the genes associated with primary metabolism, as well as the pathways associated with defense such as phytohormones and specialized metabolites, were different between the three genotypes. Measurement of benzoxazinoid levels at the three time points (11, 15, and 18 days after germination) revealed high levels in the two domesticated genotypes, while in wild emmer wheat, they were below detection level. In contrast to the benzoxazinoid levels, the trichome density was dramatically higher in the wild emmer than in the domesticated wheat. Lastly, we tested the bird cherry-oat aphid’s ( Rhopalosiphum padi ) performance and found that Chinese Spring is more resistant than the tetraploid genotypes. Conclusions: Our results show that benzoxazinoids play a more significant defensive role than trichomes. Differences between the abundance of defense mechanisms in the wild and domesticated plants were observed in which wild emmer possesses high physical defenses while the domesticated wheat genotypes have high chemical defenses. These findings provide new insights into the defense adaptations of wheat plants against aphids.
Ultrasound assessment of central venous pressure: A systematic review and meta-analysis
Authors: Deschamps Jean , Lipes Jed , Weinstock Andrew , Jayaraman Dev , Rudski Lawrence , Afilalo Jonathan 
Published: December 2019

Abstract
Background Ultrasound is increasingly relied upon to estimate central venous pressure (CVP) in the echocardiography lab and using point-of-care systems in the intensive care unit and the emergency department. However, there is uncertainty regarding the diagnostic accuracy of ultrasound-based parameters as reported in diverse studies.Methods A systematic review was performed by searching MEDLINE, EMBASE, and the Cochrane Database for studies evaluating ultrasound-based indicators of filling pressures in relation to catheterization-based CVP. Studies were screened for predefined inclusion criteria and rated for quality by duplicate observers. Standardized correlation coefficients for each ultrasound-based indicator were meta-analyzed using a random effects model.Results 3949 articles were screened and 64 met the criteria for inclusion. Inferior vena cava (IVC) diameter was assessed in 34 study measures and the pooled standardized correlation with invasive CVP was 0.74 (95% CI 0.63 to 0.84). IVC collapsibility was assessed in 20 study measures and the pooled standardized correlation with invasive CVP was -0.57 (95% CI -0.70 to -0.44). Tricuspid E/Ep was assessed in 6 study measures and the pooled standardized correlation with invasive CVP was 0.59 (95% CI 0.26 to 0.93). IVC parameters but not E/Ep remained correlated with CVP in mechanically ventilated patients, including cardiac surgery patients. Results were similar in studies featuring non-traditional users and cardiac specialists.Conclusions Echocardiographic IVC diameter, collapsibility, and tricuspid E/Ep ratio are significantly correlated with invasive CVP, albeit with important heterogeneity between studies. Most of these indicators are equally valid when applied in ventilated patients and by non-traditional users.
Carotid artery ultrasound for evaluating the degree of stenosis and plaque composition in patients with coronary heart disease
Authors: Zhu Ye , You Jia , Xu Chao , Gu Xiang 
Published: December 2019

Abstract
Background: Early screening, diagnosis, risk assessment, and intervention of intima-media thickness (IMT) and carotid plaques is critical for assessing the risk of coronary heart disease (CHD). The current study aimed to assess carotid IMT and atherosclerotic plaque composition in patients with CHD by carotid artery ultrasound and to determine the associations of various factors with CHD. Methods: 480 patients with suspected CHD underwent a duplex ultrasound of the carotid arteries and coronary angiography or coronary CT. Then, the patients were investigated and evaluated to identify both personal and medical histories of clinical evaluations, and divided into the CHD (n=325) and control (n=155) groups based on clinical symptoms and vessel lesions. Associations of clinical characteristics with ischemic lesions determined by coronary angiography or CT were examined. Screening by B-mode carotid artery ultrasonography was performed the morning after admission prior to any treatment, coronary angiography or CT. Results: Cardiac diagnostic testing was performed in 134 subjects by CT coronary angiography, while the remaining 346 patients underwent coronary angiography. Carotid plaques were mainly distributed in the common carotid artery, with a significant difference between the CHD and control groups. Plaque incidence (80%) and IMT thickness (0.84±0.21) were significantly higher in the CHD group compared with control patients (P=8.92e-12 and P=0.012 respectively). The factors significantly associated with CHD were selected into the multivariate regression model. Male subject (OR=1.569, 95%CI 1.004-2.453; P=0.048) and plaque level (OR=0.457, 95%CI 0.210-0.993; P=0.048) were significant for CHD occurrence. The carotid plaque performed significantly better than IMT and the Framingham CHD risk score for predicting CHD risk (DeLong's correlated AUC test P=5.84e-4 and P=2.52e-5, respectively). Conclusions: The present study demonstrated that carotid artery ultrasound could be an effective method for early detection of atherosclerosis, which would help prevent CHD in asymptomatic patients with advanced atherosclerosis of the carotid artery. Incorporating carotid artery ultrasound plaque composition into screen practice may perform significantly better than the Framingham CHD risk factors for predicting CHD risk.
Prevalence and factors associated with meconium stained amniotic fluid in a tertiary hospital, Northwest Ethiopia: A cross sectional study
Authors: Abate Enyew , Alamirew Kassahun , Admassu Eleni , Derbie Awoke 
Published: December 2019

Abstract
Background Meconium is a green viscous fluid and its passage normally occurs within the first 24-48 hours after birth. However, fetuses could pass meconium before or during labor and mostly intrauterine passage was found to be associated with different feto-maternal stress factors resulting in increased risk of perinatal morbidity and mortality. In Ethiopia little is known about the proportion and associated factors for meconium stained amniotic fluid (MSAF). The aim of the study was to assess the proportion and associated factors of MSAF in women who came for labor and delivery service in a tertiary hospital in Ethiopia.Methods A cross sectional study was conducted from 1st June to 31 August, 2018 on 606 laboring mothers at Felege Hiwot Referral Hospital, northwest Ethiopia. Study participants were selected using a systematic random sampling technique. Data was collected using interviewer administered structured questionnaire. Data entry and analysis were made by using Epi-data v3.1 and SPSS v24, respectively. Both descriptive & analytical statistics were computed. Statistical significance was set at P < 0.05. Logistic regression was used to explore factors associated with MSAF.Results The proportion of MSAF was at 149 (24.6%) [95%CI: 21.3-28.2%]. Nonreassuring fetal heart rate pattern (AOR: 21.9,95% CI: 10.96-43.83), post term pregnancy (4.54,95% CI: 2.24-9.20), duration of labor more than 15 hours (AOR: 2.83,95% CI: 1.76-4.53), pregnancy induced hypertension (AOR: 2.43, 95% CI: 1.45-4.05), oligohydramnios (AOR: 2.53, 95% CI: 1.25-5.12) inter pregnancy interval less than 2 years (AOR: 2.24,95% CI: 1.12-4.51) and monthly family income less than 5000 Ethiopian Birr (185 United States Dollar) (AOR: 2.03, 95% CI:1.18-3.51) were significantly associated with MSAF.Conclusions The proportion of MSAF was at 24.6% which was higher than a previous study done in Ethiopia and elsewhere. Non-reassuring fetal heart rate pattern, post term pregnancy, duration of labor more than 15 hours, pregnancy induced hypertension, oligohydramnios, inter pregnancy interval less than 2 years and monthly family income less than 5000 Ethiopian Birr were factors associated with an increased risk for MSAF. Health professionals should assess laboring women for the presence of these factors and should stay alert to detect MSAF early and to act accordingly.
Per-head cost of patients responding to eltrombopag and rituximab in the treatment of primary immune thrombocytopenia in Spain.
Authors: Gonzalez-Porras José Ramón , Parrondo-García Francisco Javier , Anguita Eduardo 
Published: December 2019

Abstract
Background: Splenectomy, thrombopoietin receptor agonists (TPO-RAs) and rituximab are the second line treatments for steroid resistant adult primary immune thrombocytopenia (ITP). The last two are becoming the most widely used to avoid splenectomy adverse effects and inconveniences. However, the choice between rituximab and TPO-RAs is unclear. Therefore, the treatment cost may be of particular interest to prioritize the therapy option. Our aim is to know the cost per patient after a 6 months treatment in a European Health Service of rituximab compared to the TPO-RA eltrombopag. Methods: A 26-weeks decision tree model have been developed to assess the cost of treatment response of adult patients with chronic-refractory ITP to eltrombopag and rixutimab under the perspective of the Spanish National Health system. Effectiveness were obtained from literature and cost from the official rates. Costs were expressed in €(2018). Due to the short period of assessment, no discount rate was applied. Results: Average cost per patient after a 6 months treatment was similar for eltrombopag and rituximab, although the first one was slightly higher. However, the greater response rate of eltrombopag decreases the bleeding costs, resulting in a 29% higher cost with rituximab treatment. Eltrombopag cost is always lesser, except in the sensitivity analysis in which the patient received a daily dose of 75 mg of eltrombopag –a scenario where eltrombopag cost is 48€ higher than that of rituximab. Conclusions: The treatment cost of rituximab, including monitoring and bleeding costs is higher than eltrombopag, favouring the last one over rituximab treatment.
Clinical characteristics, antibiotic-resistant patterns and prognostic factors in cancer patients with nosocomial infections caused by extended-spectrum beta-lactamase-producing Escherichia coli: a retrospective study from 2013 to 2019
Authors: Jiang Ai-min , Shi Xin , Liu Na , Liang Xuan , Ruan Zhi-Ping , Zheng Xiao-Qiang , Fu Xiao , Tian Tao , Yao Yu 
Published: December 2019

Abstract
Background: Nosocomial infections due to Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) is increasing worldwide. This study aimed to describe the clinical characteristics, antibiotic-resistant patterns, and prognostic factors associated with nosocomial infections caused by ESBL-PE in cancer patients. Methods: This retrospectively analyzed patients with nosocomial infections caused by E. coli from August 2013 to May 2019 and was conducted to investigate the risk factors, clinical features, outcomes, and antibiotic-resistant patterns of these infections. Results: Of the 1008 nosocomial infection episodes, 265 patients suffered from infections with E. coli, and 155 episodes were caused by ESBL-PE. A multivariate analysis showed that the length of antibiotics treatment more than 6.93 days was an independent risk factor for nosocomial infections in cancer patients caused by ESBL-PE. ECOG performance status score more than 2, presence of respiratory tract infection, septic shock, lymphocytopenia, and hypoproteinemia were independent risk factors for 30-day mortality in cancer patients caused by ESBL-PE. Antimicrobial susceptibility showed that the isolated ESBL-PE were highly resistant to aztreonam and third-generation cephalosporins. Conclusions: The length of antibiotics treatment more than 6.93 days increased the risk ratio for ESBL-PE caused nosocomial infections. However, there was no significant difference in the prognoses of patients with ESBL-PE and non-ESBL-PE caused nosocomial infections. ECOG performance status score more than 2, presence of respiratory tract infection, septic shock, lymphocytopenia, and hypoproteinemia were independent risk factors for 30-day mortality in cancer patients with nosocomial infections caused by E. coli. The isolated ESBL-PE were highly resistant to aztreonam and third-generation cephalosporins.
First description of class 1 integron in typhoidal Salmonella isolated from clinical and lettuce samples in Burkina Faso.
Authors: SOMDA Namwin Siourimè , Bonkoungou Juste Isidore Ouindgueta , Traoré Oumar , Sambe-Ba Bissoume , Wane Abdoul Aziz , Traoré Yves , Savadogo Aly 
Published: December 2019

Abstract
Background: In Burkina Faso, dirty water, in particular those of the stoppings and the gutter are used for irrigation of vegetables. The aim of this study is to contribute to the knowledge on the molecular level of Salmonella circulating in the hospitals and environment next to hospitals in Burkina Faso. Methods: Salmonella isolated from diarrhea stools between 2009 to 2015 and lettuce samples isolated in 2014 in Burkina Faso were characterized by simple Polymerase Chain Reaction using specific primers. Sequencing was performed using the BigDye terminator protocol on the ABI PRISM 310. The sequences obtained corresponding were searched using the BlastN program.Results: Out of 100 Salmonella isolated, 53% were from human and 47% from lettuce samples. Globally, the highest prevalence was observed with invA, misL, pipD, orfL and spvR genes in 97%, 96%; 74%; and 21%. Forty of these isolates carried class 1 integron, 31 from clinical samples and 9 from lettuce samples. Sequencing showed different gene with aadA1 in 13/15 strains, aadA7 and aac(3)-Id in 2/15 strains. Eight percent (8/100) of Salmonella harbored gyrB and parE genes. Sequencing showed no mutation in these genes. Three distinct Pulsed-Field Gel Electrophoresis (PFGE) types were observed from clinical samples with 90-95% similarity in each case. All Salmonella from lettuce had similar pulsotypes. Conclusion: This study showed that lettuce is a potential source of transmission of Salmonella causing diarrhea among human in Burkina Faso.
Incidence and Predictors of tuberculosis among HIV patients after initiation of ART treatment in Ethiopia: A systematic review and Meta-analysis
Authors: Azanaw Melkalem Mamuye , Derseh Nebiyu Mekonen , Yetemegn Gebeyehu Shumuye , Angaw Dessie Abebaw 
Published: December 2019

Abstract
Background: Tuberculosis is the oldest infectious disease and it is still the leading cause of morbidity and mortality worldwide. Even though, several primary studies have been conducted on incidence of tuberculosis among HIV infected individuals in Ethiopia, national level TB incidence is unknown. Therefore, this systematic review and meta-analysis study is aimed to study TB incidence rate and its predictors among HIV infected individuals in Ethiopia. Methods: We conducted extensive search of literature as indicated in the guideline of reporting systematic review and meta-analysis (PRISMA). The databases used were PubMed, Google Scholar, HINARI and Scopus literature. Searching terms used were “incidence”, “predictors”, “Tuberculosis”, “HIV infected patients”, and “Ethiopia”. We used Joanna Briggs Institute (JBI) Meta-Analysis of Statistics Assessment and Review Instrument for critical appraisal of studies. The meta-analysis and Meta regressions were conducted using STATA 14 software. The pooled meta-analysis and Meta regression were computed to present the pooled incidence rate and predictors of tuberculosis among HIV infected patients after initiation of ART therapy with a 95% confidence interval Results: Among a total of 189 studies, 11 studies were included in this analysis. The estimated pooled incidence rate of TB per 100-person year observation (PYO) among HIV infected patients after initiation of ART therapy was 4.8(95% CI: 3.69–5.83). In subgroup analysis, the estimated pooled incidence of tuberculosis showed a slightly difference between Adults and children after initiation of ART treatment, which was 4.3 (95% CI: 2.96, 5.71) and 5.0 (95% CI: 3.51, 6.50), respectively. Significant predictor of pooled estimate of meta-analysis showed that being anemic patients (2.30, 95% CI: 1.75, 3.02); on WHO clinical stage III & IV (2.26, 95% CI (1.70, 3.02); and not on CPT (2.16, 95% CI: 1.23, 3.72) and a Meta regression revealed that CD4 <200 cells/mm 3 (2.12, 95% CI: 1.17, 3.86) was positively significant predictors among Adults. Conclusions: The current systematic review and meta-analysis showed that the pooled incidence of TB among HIV patients was found to lower than WHO 2018 national estimate. Being anemic, WHO stage III& IV, not on CPT, CD4 <200cells/µl and being male were significant predictors of Tuberculosis. Therefore, the existing strategies to decrease TB should be strengthening.