bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasmonic transmitted optical differentiator based on the subwavelength gold gratings
Authors: Yang Weiji , Yu Xuanyi , Zhang Jialin , Deng Xiaoxu 
Published: March 2020

A nanoscale plasmonic optical differentiator based on subwavelength gold gratings is investigated theoretically and experimentally without Fourier transform lenses and prisms. In the vicinity of surface plasmon resonance (SPR), the transfer function of subwavelength gold gratings is derived by optical scattering matrix theory. Simulated by the finite difference time domain (FDTD) method, the wavelengths of optical spatial differentiation performed by subwavelength gold gratings are tuned by the grating period and duty cycle, while the throughput of edge extraction is mainly adjusted by the grating thickness. Without Fourier transformation, the fabricated plasmonic optical differentiator experimentally achieves real-time optical spatial differentiation in transmission and implements SPR enhanced high-throughput edge extraction of a microscale image with a resolution of 10 µm at 650 nm, which has potential applications in areas of optical analog computing, optical imaging, and optical information processing.
Highly efficient stimulated Raman scattering of sub-picosecond laser pulses in BaWO4 for 10.6  µm difference frequency generation
Authors: Kinyaevskiy I. O. , Kovalev V. I. , Danilov P. A. , Smirnov N. A. , Kudryashov S. I. , Seleznev L. V. , Dunaeva E. E. , Ionin A. A. 
Published: March 2020

Transient stimulated Raman scattering (SRS) of 0.3 ps 515 nm laser pulses in

B
a
W

O
4

crystal was experimentally demonstrated with efficiency up to

∼

20

%

for the Stokes component with a wavenumber of

∼

925

c
m

−
1

in a simple single-pass geometry. This anomalous high efficiency was obtained due to the laser pulse self-phase modulation resulting in spectral broadening and seeding the SRS. The applicability of seed pulse production for a high-pressure sub-picosecond

C
O

2

laser amplifier via difference frequency generation in

L
i
G
a
S

2

crystal was numerically verified.
Prophylactic Endoscopic Clipping Does Not Prevent Delayed Postpolypectomy Bleeding in Routine Clinical Practice: A Propensity Score–Matched Cohort Study
Authors: Forbes Nauzer , Hilsden Robert J. , Lethebe Brendan Cord , Maxwell Courtney M. , Lamidi Mubasiru , Kaplan Gilaad G. , James Matthew T. , Razik Roshan , Hookey Lawrence C. , Ghali William A. , Bourke Michael J. , Heitman Steven J. 
Published: March 2020

Introduction:
Delayed postpolypectomy bleeding (DPPB) is a relatively common adverse event. Evidence is conflicting on the efficacy of prophylactic clipping to prevent DPPB, and real-world effectiveness data are lacking. We aimed to determine the effectiveness of prophylactic clipping in preventing DPPB in a large screening-related cohort.

METHODS:
We manually reviewed records of patients who underwent polypectomy from 2008 to 2014 at a screening facility. Endoscopist-, patient- and polyp-related data were collected. The primary outcome was DPPB within 30 days. All unplanned healthcare visits were reviewed; DPPB cases were adjudicated by committee using a criterion-based lexicon. Multivariable logistic regression was performed, yielding adjusted odds ratios (AORs) for the association between clipping and DPPB. Secondary analyses were performed on procedures where one polyp was removed, in addition to propensity score–matched and subgroup analyses.

RESULTS:
In total, 8,366 colonoscopies involving polypectomy were analyzed, yielding 95 DPPB events. Prophylactic clipping was not associated with reduced DPPB (AOR 1.27; 0.83–1.96). These findings were similar in the single-polyp cohort (n = 3,369, AOR 1.07; 0.50–2.31). In patients with one proximal polyp ≥20 mm removed, there was a nonsignificant AOR with clipping of 0.55 (0.10–2.66). Clipping was not associated with a protective benefit in the propensity score–matched or other subgroup analyses.

DISCUSSION:
In this large cohort study, prophylactic clipping was not associated with lower DPPB rates. Endoscopists should not routinely use prophylactic clipping in most patients. Additional effectiveness and cost-effectiveness studies are required in patients with proximal lesions ≥20 mm, in whom there may be a role for prophylactic clipping.
Utilization of Coconut Shell as Cr2O3 Catalyst Support for Catalytic Cracking of Jatropha Oil into Biofuel
Authors: Aziz Isalmi , Kurnianti Yessinta , Saridewi Nanda , Adhani Lisa , Permata Wahyu 
Published: March 2020

Coconut shell waste is a waste that has a high carbon content. Carbon in coconut shell waste can be converted into activated carbon having a large surface area. This potential property is suitable to apply the coconut shell as catalyst support. To increase the catalytic activity, metal oxides such as Cr2O3 are impregnated. The purpose of this study is to synthesize Cr2O3/carbon catalyst and test its catalytic activity on catalytic cracking of Jatropha oil. The first stage was the synthesis of activated carbon and the determination of its proximate and ultimate. The second step was impregnation to produce Cr2O3/carbon catalyst. Furthermore, X-Ray Diffraction to determine crystallinity, Surface Area Analyzer to identify its surface area and Fourier Transform Infrared to analyze functional groups. Then the catalytic activity was tested on the catalytic cracking of Jatropha oil. In addition, the chemical compound composition and biofuel selectivity of the catalytic cracking product was determined using Gas Chromatography-Mass Spectrometer. Proximate analysis results showed that activated carbon contains 9%, 1%, 23%, and 67% of water, ash, evaporated substances, and bound carbon, respectively. The results of the ultimate analysis resulted in carbon (C), hydrogen (H), and nitrogen (N) contents of 65.422%, 3.384%, and 0.465%, correspondingly. The catalyst crystallinity test showed the presence of Cr2O3 peaks at 2θ: 24.43°; 33.47° and 36.25° according to JCPDS No. 84-1616. In the absorption area of 400-1000 cm-1 and the range of 2000 cm-1 showed the presence of Cr-O stretching due to Cr2O3 adsorbed into the activated carbon structure. The surface area of activated carbon and Cr2O3/carbon catalysts with a concentration of 1.3, and 5% was 8.930 m2/g; 47.205 m2/g; 50.562 m2/g; and 38.931 m2/g, respectively. The catalytic activity test presented that the best performance was showed by Cr2O3/carbon catalyst with a concentration of 5% indicated by conversion of Jatropha oil into biofuel of 67.777% with gasoline selectivity, kerosene, and diesel of 36.97%, 14.87%, and 15.94%, correspondingly.
Umowa urbanistyczna jako przykład umowy administracyjnej na tle polskiego i europejskiego porządku prawnego
Authors: Kruś Maciej 
Published: March 2020

The subject of the article is an attempt to show that concluding an urban contract is a form of public administration activity of an administrative nature, not a civil one. As a result of the contract, an administrative-legal relationship is established. Its characteristic feature is that in order for this relationship to arise it is necessary for the other party to agree. The other party is an investor who is supposed to carry out the project at his own expense. The basis for the conclusion of the contract is not the freedom of contracting, but administrative law specifying the competence of the administration to conclude a contract as well as determining the acceptable content of the contract. The urban contract is therefore an administrative contract. The article also presents the basic features of an administrative contract. In the study, the achievements of Polish and German doctrine were used. The administra­tive contract is not regulated under Polish law but relevant provisions are contained in the German Act on Administrative Proceedings. In addition, a public law contract has been described as an instrument of action in the implementation of European Union law. In this context, two cases were distinguished, i.e. the conclusion of a contract by national authorities and the conclusion of a contract by the Union institutions. In the latter case, it was necessary to interpret the provisions of the Treaty on the European Union and the Treaty on the Functioning of the European Union. The characteristics of the administrative contract which make it a good means of establishing an administrative-legal relationship are also presented. Of particular importance is the opportunity of creating the content of the relationship by the entities involved. This enables the formation of individual provisions adapted to a specific case. At the same time, because the consent of both parties is needed to conclude a contract, such an administrative contract protects the interests of both parties to the legal relationship. Public administration’s ability to act in spe­cific situations must be ensured and for that reason the administrative contract will probably develop further.
Alkali Lignin Catalytic Hydrogenolysis with Biofuel Production
Authors: Shimanskaya Elena I. , Sulman Esther M. , Sulman Mikhail G. , Tiamina Irina Yu. 
Published: March 2020

AbstractIn this paper synthesized palladium (Pd)-containing catalysts were used in the hydrogenolysis of lignin in the presence of a hydrogen donor solvent, i-propanol, to obtain liquid fuel components. A study of the influence of the catalyst support nature, catalyst preparation method and supercritical solvent nature on the lignin depolymerization was completed. It was found that the use of Pd-containing catalysts results in the formation of aromatic compounds (mainly benzene and toluene) for both supercritical solvents used (i-propanol and CO2). The maximum conversion of lignin (50 %) was achieved when the supercritical i-propanol was used and maximum selectivity to aromatics (over 70 %) was observed in the presence of the Pd-containing catalyst synthesized by hydrothermal deposition on the polymeric matrix of hyper-crosslinked polystyrene.
Quantum chemical exercise linking computational chemistry to general chemistry topics
Authors: Simpson Scott , Evanoski-Cole Ashley , Gast Kellie , Wedvik Madeleine C. , Schneider Patrick W. , Klingensmith Isaac 
Published: March 2020

Abstract
Students in a second semester general chemistry course used quantum chemical calculations to investigate and reinforce general chemistry concepts. Students explored the isomers of hypochlorous acid, made predictions of miscibility via dipole moments calculated from ab-initio means, experimentally validated/disqualified their miscibility predictions, and used molecular models to visualize intermolecular attraction forces between various compounds. Student responses in pre-/post-exercise assessments show evidence of student learning. Responses in pre-/post-exercise surveys showed an increase in student understanding of basic concepts and of the importance of quantum mechanics in common general chemistry topics.
Prepare a catalyst consist of rare earth minerals to denitrate via NH3-SCR
Authors: Wang Jian , Zhu Chao , Li Baowei , Gong Zhijun , Meng Zhaolei , Xu Guodong , Wu Wenfei 
Published: March 2020

AbstractTo research the roles of rare earth minerals in denitrification via the NH3-SCR, a mixture was made by certain ratio of rare earth concentrates and rare earth tailings, then treated by microwave roasting, and acids and bases to form a denitrification catalyst. The mineral phase structure and surface morphology of the catalyst were characterized by XRD, BET, SEM and EDS. The surface properties of the catalyst were tested by TPD and XPS methods, and the denitrification activity of the catalyst was evaluated in a denitrification reactor. The results showed that the denitrification efficiency increased up to 82% with complete processing. XRD, BET, SEM, and EDS spectrum analysis stated that the treated minerals contained cerium oxides and Fe−Ce composite oxides. The surface of the modified minerals became rough and porous, the surface area increased, and the surface-active sites were exposed. The results of NH3-TPD and NO-TPD showed that the catalyst surface could gradually adsorb more NH3 and NO after each step. XPS analysis indicated that there were more Ce3+, Fe2+, and lattice oxygen in rare earth minerals catalyst after each treatment step.
Review on modeling and application of chemical mechanical polishing
Authors: Zhao Gaoyang , Wei Zhen , Wang Weilei , Feng Daohuan , Xu Aoxue , Liu Weili , Song Zhitang 
Published: March 2020

Abstract
With the development of integrated circuit technology, especially after entering the sub-micron process, the reduction of critical dimensions and the realization of high-density devices, the flatness between integrated circuit material layers is becoming more and more critical. Because conventional mechanical polishing methods inevitably produce scratches of the same size as the device in metal or even dielectric layers, resulting in depth of field and focus problems in lithography. The first planarization technique to achieve application is spin on glass (SOG) technology. However, this technology will not only introduce new material layers, but will also fail to achieve the global flattening required by VLSI and ULSI technologies. Moreover, the process instability and uniformity during spin coating do not meet the high flatness requirements of the wafer surface. Also, while some techniques such as reverse etching and glass reflow can achieve submicron level regional planarization. After the critical dimension reaches 0.35 microns (sub-micron process), the above methods cannot meet the requirements of lithography and interconnect fabrication. In the 1980s, IBM first introduced the chemical mechanical polishing (CMP) technology used to manufacture precision optical instruments into its DRAM manufacturing [1]. With the development of technology nodes and critical dimensions, CMP technology has been widely used in the Front End Of Line (FEOL) and Back End Of Line (BEOL) processes [2]. Since the invention of chemical mechanical polishing, scientists have not stopped studying its internal mechanism. From the earliest Preston Formula (1927) to today’s wafer scale, chip scale, polishing pad contact, polishing pad - abrasive - wafer contact and material removal models, there are five different scale models from macro to the micro [3]. Many research methods, such as contact mechanics, multiphase flow kinetics, chemical reaction kinetics, molecular dynamics, etc., have been applied to explain the principles of chemical mechanical polishing to establish models. This paper mainly introduces and summarizes the different models of chemical mechanical polishing technology. The various application scenarios and advantages and dis-advantages of the model are discussed, and the development of modeling technology is introduced.
Novel colchicine conjugate with unusual effect on the microtubules of cancer cells
Authors: Zefirova Olga N. , Nurieva Evgenia V. , Wobith Birgit , Schulz Svetlana , Zefirov Nikolay A. , Kuznetsov Sergei A. 
Published: March 2020

Abstract
Colchicine derivative bearing substituted bispidine moiety, namely N-{7-(3,7-Di-(tert-butoxycarbonyl)-1,5-dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-yl)-oxy-7-oxoheptanoyl}-N-deacetylcolchicine, was synthesized and tested for its effect on the net of microtubules (MT) in lung cancer cells A549. The compound induced not only MT depolymerization but stimulated the formation of small tubulin aggregates and long tubulin fibrils localized mainly around nuclei. The assemblies were morphologically different from tubulin clusters induced by structurally related anticancer agent tubuloclustin. The biotests data demonstrate that the depolymerization takes place for both pure tubulin and tubulin in cellulo, while fibrils are formed only in the cells. The research data of structure–activity relationship for several similar colchicine derivatives synthesized in the work give evidence for the proposition that the initial conjugate may interact not only with tubulin and MT in the cells, but also with MT-associated proteins, involved in the process of tubulin polymerization. The ability to affect simultaneously MAP – tubulin interactions opens attractive prospects in the design of novel anticancer agents.
A Computational Mechanism for Seeing Dynamic Deformation
Authors: Kawabe Takahiro , Sawayama Masataka 
Published: March 2020

AbstractHuman observers perceptually discriminate the dynamic deformation of materials in the real world. However, the psychophysical and neural mechanisms responsible for the perception of dynamic deformation have not been fully elucidated. By using a deforming bar as the stimulus, we showed that the spatial frequency of deformation was a critical determinant of deformation perception. Simulating the response of direction-selective units (i.e., MT pattern motion cells) to stimuli, we found that the perception of dynamic deformation was well explained by assuming a higher-order mechanism monitoring the spatial pattern of direction responses. Our model with the higher-order mechanism also successfully explained the appearance of a visual illusion wherein a static bar apparently deforms against a tilted drifting grating. In particular, it was the lower spatial frequencies in this pattern that strongly contributed to the deformation perception. Finally, by manipulating the luminance of the static bar, we observed that the mechanism for the illusory deformation was more sensitive to luminance than contrast cues.
Deletion of Voltage-Gated Calcium Channels in Astrocytes during Demyelination Reduces Brain Inflammation and Promotes Myelin Regeneration in Mice
Authors: Zamora Norma N. , Cheli Veronica T. , Santiago González Diara A. , Wan Rensheng , Paez Pablo M. 
Published: March 2020

To determine whether Cav1.2 voltage-gated Ca2+channels contribute to astrocyte activation, we generated an inducible conditional knock-out mouse in which the Cav1.2 α subunit was deleted in GFAP-positive astrocytes. This astrocytic Cav1.2 knock-out mouse was tested in the cuprizone model of myelin injury and repair which causes astrocyte and microglia activation in the absence of a lymphocytic response. Deletion of Cav1.2 channels in GFAP-positive astrocytes during cuprizone-induced demyelination leads to a significant reduction in the degree of astrocyte and microglia activation and proliferation in mice of either sex. Concomitantly, the production of proinflammatory factors such as TNFα, IL1β and TGFβ1 was significantly decreased in the corpus callosum and cortex of Cav1.2 knock-out mice through demyelination. Furthermore, this mild inflammatory environment promotes oligodendrocyte progenitor cells maturation and myelin regeneration across the remyelination phase of the cuprizone model. Similar results were found in animals treated with nimodipine, a Cav1.2 Ca2+channel inhibitor with high affinity to the CNS. Mice of either sex injected with nimodipine during the demyelination stage of the cuprizone treatment displayed a reduced number of reactive astrocytes and showed a faster and more efficient brain remyelination. Together, these results indicate that Cav1.2 Ca2+channels play a crucial role in the induction and proliferation of reactive astrocytes during demyelination; and that attenuation of astrocytic voltage-gated Ca2+influx may be an effective therapy to reduce brain inflammation and promote myelin recovery in demyelinating diseases.SIGNIFICANCE STATEMENTReducing voltage-gated Ca2+influx in astrocytes during brain demyelination significantly attenuates brain inflammation and astrocyte reactivity. Furthermore, these changes promote myelin restoration and oligodendrocyte maturation throughout remyelination.
Sex hormone-binding globulin, androgens and mortality: the KORA-F4 cohort study
Authors: Schederecker Florian , Cecil Alexander , Prehn Cornelia , Nano Jana , Koenig Wolfgang , Adamski Jerzy , Zeller Tanja , Peters Annette , Thorand Barbara 
Published: March 2020

Objective
Sex hormone-binding globulin (SHBG) and androgens have been associated with mortality in women and men, but controversy still exists. Our objective was to investigate associations of SHBG and androgens with all-cause and cause-specific mortality in men and women.

Design
1006 men and 709 peri- and postmenopausal women (age range: 45–82 years) from the German population-based KORA F4 cohort study were followed-up for a median of 8.7 years.

Methods
SHBG was measured with an immunoassay, total testosterone (TT) and dihydrotestosterone (DHT) with mass-spectrometry in serum samples and we calculated free testosterone (cFT). To assess associations between SHBG and androgen levels and mortality, we calculated hazard ratios (HRs) with 95% CIs using Cox proportional-hazards models.

Results
In the cohort, 128 men (12.7%) and 70 women (9.9%) died. In women, we observed positive associations of SHBG with all-cause (HR: 1.54, 95% CI: 1.16–2.04) and with other disease-related mortality (HR: 1.86, 95% CI: 1.08–3.20) and for DHT with all-cause mortality (HR: 1.32, 95% CI: 1.00–1.73). In men, we found a positive association of SHBG (HR: 1.24 95% CI: 1.00–1.54) and inverse associations of TT (HR: 0.87, 95% CI: 0.77–0.97) and cFT (HR: 0.84, 95% CI: 0.73–0.97) with all-cause mortality. No other associations were found for cause-specific mortality.

Conclusions
Higher SHBG levels were associated with increased risk of all-cause mortality in men and women. Lower TT and cFT levels in men and higher DHT levels in women were associated with increased risk of all-cause mortality. Future, well-powered population-based studies should further investigate cause-specific mortality risk.
Thyroid carcinoma with atypical metastasis to the pituitary gland and unexpected postmortal diagnosis
Authors: Popławska-Kita Anna , Wielogórska Marta , Poplawski Łukasz , Siewko Katarzyna , Adamska Agnieszka , Szumowski Piotr , Myśliwiec Piotr , Myśliwiec Janusz , Reszeć Joanna , Kamiński Grzegorz , Dzięcioł Janusz , Tobiaszewska Dorota , Szelachowska Małgorzata , Krętowski Adam Jacek 
Published: March 2020

Summary
Papillary thyroid gland carcinoma is the most common type of malignancy of the endocrine system. Metastases to the pituitary gland have been described as a complication of papillary thyroid cancer in few reported cases since 1965. We report the case of a 68-year-old female patient with a well-differentiated form of thyroid gland cancer. Despite it being the most common malignant cancer of the endocrine system, with its papillary form being one of the two most frequently diagnosed thyroid cancers, the case we present is extremely rare. Sudden cardiac arrest during ventricular fibrillation occurred during hospitalization. Autopsy of the patient revealed papillary carcinoma of the thyroid, follicular variant, with metastasis to the sella turcica, and concomitant sarcoidosis of heart, lung, and mediastinal and hilar lymph nodes. Not only does atypical metastasis make our patient’s case most remarkable, but also the postmortem diagnosis of sarcoidosis makes her case particularly unusual.

Learning points:

The goal of presenting this case is to raise awareness of the clinical heterogeneity of papillary cancer and promote early diagnosis of unexpected metastasis and coexisting diseases to improve clinical outcomes.

Clinicians must be skeptical. They should not fall into the trap of diagnostic momentum or accept diagnostic labels at face value. Regardless of the potential mechanisms, clinicians should be aware of the possibility of the coexistence of thyroid cancer and sarcoidosis as a differential diagnosis of lymphadenopathy.

This case highlights the importance of the diagnostic and therapeutic planning process and raises awareness of the fact that one uncommon disease could be masked by another extremely rare disorder.