bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hiệu quả nuôi cấy phôi giữa hai hệ thống tủ cấy benchtop có hoặc không sử dụng khí trộn: một nghiên cứu chia noãn
Authors: Ha Thi Diem Uyen , Tran Tu Cam , Pham Thieu Quan , Huynh Gia Bao , Ho Manh Tuong 
Published: July 2020

Mục tiêu: So sánh hiệu quả nuôi cấy phôi giữa 2 hệ thống tủ cấy benchtop có và không có sử dụng khí trộn sẵn.
Đối tượng và phương pháp nghiên cứu: Nghiên cứu chia noãn được thực hiện từ 02/2017 - 04/2017 tại IVFMD, bệnh viện Mỹ Đức. Tiêu chuẩn nhận bệnh: bệnh nhân ≤ 38 tuổi; số chu kỳ điều trị trước đó ≤ 2; nuôi cấy phôi ngày 5. Tiêu chuẩn loại: các chu kỳ xin cho noãn; IVM; tinh trùng phẫu thuật; bất thường tử cung, vùng chậu. Tại thời điểm chọc hút noãn, tiến hành chia cụm COCs thành 2 nhóm (1) nuôi cấy phôi bằng tủ cấy dùng khí trộn sẵn (tủ cấy BT37, Origio, Đan Mạch) và (2) nuôi cấy phôi không sử dụng hệ thống khí trộn sẵn (tủ cấy G185, K-system, Đan Mạch). Nếu số cụm COCs là số lẻ thì cụm COC dư ra sẽ được chia vào nhóm 2. Kết cục chính là tỷ lệ phôi nang tốt. Kết cục phụ là tỷ lệ thụ tinh và tỷ lệ tạo phôi nang.
Kết quả: Có 60 bệnh nhân tham gia vào nghiên cứu, trong đó có 735 cụm COCs nuôi cấy ở nhóm 1 và 765 cụm COCs nuôi cấy ở nhóm 2. Tỷ lệ phôi nang tốt không có sự khác biệt thống kê giữa 2 nhóm (39.5% so với 38.2%; p = 0.89). Không có sự khác biệt về tỷ lệ thụ tinh (90.0% so với 92.0%, p = 0.20) cũng như tỷ lệ tạo phôi nang (55.1% so với 56.6%, p = 0.87) giữa 2 nhóm.
Kết luận: Hệ thống tủ cấy có sử dụng khí trộn có hiệu quả tương đương hệ thống tủ cấy không sử dụng khí trộn về kết cục nuôi cấy phôi nang. Việc chọn lựa sử dụng hệ thống tủ cấy nào phụ thuộc vào số chu kỳ và quy trình quản lí sử dụng tại từng labo thụ tinh trong ống nghiệm.
Chẩn đoán trước sinh bất thường nhiễm sắc thể ở thai có tứ chứng Fallot
Authors: Bui Hai Nam , Tran Danh Cuong , Nguyen Thi Hiep Tuyet , Nguyen Hai Long 
Published: July 2020

Mục tiêu: Mô tả đặc điểm nhiễm sắc thể (NST) ở thai có tứ chứng Fallot (Tetralogy of Fallot - TOF).
Đối tượng và phương pháp nghiên cứu: Mô tả cắt ngang 51 thai được chẩn đoán TOF trên siêu âm, được chọc ối và sử dụng kỹ thuật BoBs và lập karyotype để phân tích NST thai.
Kết quả: Tổng số 51 thai có TOF: tuổi thai trung bình khi siêu âm là 22,2 tuần, tuổi thai chọc ối là 23,1 tuần. Tỷ lệ thai có TOF đơn thuần là 86,3%, và TOF phối hợp với cơ quan khác ngoài tim là 11,7%. Tỷ lệ thai có bất thường NST là 29,4% (15/51). Trong đó bất thường về số lượng NST là 6/15 và bất thường cấu trúc là 9/15. Trong nhóm bất thường về cấu trúc NST thì hội chứng Digeorge chiếm số lượng lớn 8/9 trường hợp.
Kết luận: Phát hiện bất thường NST ở thai có TOF là cơ sở để bác sĩ sản khoa thực hiện tư vấn di truyền và chẩn đoán trước sinh.
Nghiên cứu một số yếu tố liên quan đến kết quả sử dụng vòng nâng cổ tử cung trong điều trị dự phòng sẩy thai và sinh non ở Bệnh viện Phụ Sản Hải Phòng
Authors: Nguyen Van Loi , Luu Vu Dung , Vu Thi Minh Phuong , Vu Van Tam 
Published: July 2020

Nghiên cứu mô tả cắt ngang trên 125 thai phụ đã được đặt vòng nâng cổ tử cung tại Bệnh viện Phụ Sản Hải Phòng từ tháng 4/2016 đến tháng 4/2018.
Mục tiêu: Nghiên cứu một số yếu tố liên quan đến kết quả sử dụng vòng nâng cổ tử cung trong điều trị dự phòng sẩy thai và sinh non ở Bệnh viện Phụ Sản Hải Phòng.
Kết quả: Tuổi thai trung bình khi sinh ở những thai phụ đặt vòng nâng cổ tử cung (CTC) là 34,7±4,9 tuần, tỷ lệ sinh từ 28 tuần đến đủ tháng là 91,2%, tỷ lệ sơ sinh sống là 90,4%. Các yếu tố ảnh hưởng có ý nghĩa thống kê đến hiệu quả vòng nâng CTC: điều trị phối hợp (OR=0,1, 95%CI: 0,03-0,4), tuổi thai khi đặt vòng nâng CTC (OR=4,0, 95%CI: 1,6-8,3), tiền sử sinh non (OR=3,5, 95%CI: 1,6-7,9), tiền sử khâu vòng CTC (OR=3,7, 95%CI: 1-14), xuất hiện cơn co tử cung sau đặt vòng nâng CTC (OR=2,6, 95%CI: 1,0-6,4).
Kết luận: Các yếu tố điều trị phối hợp (thuốc/ hoặc phối hợp khâu vòng CTC); đặt vòng nâng CTC khi tuổi thai dưới 20 tuần làm giảm tỷ lệ sinh non khi đặt vòng nâng cổ tử cung (p<0,05); tiền sử khâu vòng cổ tử cung, tiền sử sinh non làm tăng tỷ lệ sinh non khi đặt vòng nâng CTC (p<0,05).
Nhận xét kết quả của kỹ thuật LEEP điều trị tổn thương cổ tử cung tại Bệnh viện Phụ sản Trung Ương
Authors: Nguyen Van Thang , Pham Tri Hieu 
Published: July 2020

Kỹ thuật điều trị LEEP cổ tử cung là phương pháp cắt bỏ các tổn thương tiền ung thư tại cổ tử cung bằng vòng điện.
Mục tiêu: Nhận xét các đặc điểm của đối tượng nghiên cứu; hiệu quả và tính an toàn của kỹ thuật LEEP tại Bệnh viện Phụ sản Trung ương.
Phương pháp nghiên cứu: Mô tả, theo dõi dọc trên 95 bệnh nhân từ tháng 6/2018 đến tháng 3/2019.
Kết quả: Tỷ lệ nhiễm HPV type nguy cơ cao là 76,8%, tỷ lệ xét nghiệm tế bào âm đạo bất thường là: LSIL: 31,7%, HSIL: 14,7%, ASCUS – H 6,3%, các bất thường biểu mô tuyến 5,3%. Giải phẫu bệnh sau LEEP: CIN I: 21,1%, CIN II: 14,7%, CIN III: 8,4%, CIS: 4,2%, ung thư biểu mô vảy xâm lấn: 1,1%. Có 13/95 bệnh nhân sau LEEP được chỉ định mổ cắt tử cung vì các tổn thương từ CIN III trở lên. Tỷ lệ đốt điện, chèn mèche trong thủ thuật tương ứng 91,6% và 94,7%. Tỷ lệ chảy máu trong vòng 6 tiếng sau LEEP là 6,3%, trong vòng 1 tháng là 2,4%, không có trường hợp nào nhiễm trùng. Theo dõi sau 6 tháng chưa phát hiện trường hợp nào tái phát.
Kết luận: LEEP là phương pháp điều trị hiệu quả, an toàn và thuận tiện,
Optimised degradation correction for SCIAMACHY satellite solar measurements from 330 to 1600 nm by using the internal white light source
Authors: Hilbig Tina , Bramstedt Klaus , Weber Mark , Burrows John P. , Krijger Matthijs 
Published: July 2020

Abstract. SCIAMACHY (SCanning Imaging Absorption spectroMeter for Atmospheric CHartographY) on-board the European Environmental Satellite (Envisat)
provided spectrally resolved measurements in the wavelength range from 0.24 to 2.4 µm by looking into the Earth's atmosphere using different viewing geometries (limb, nadir, solar, and lunar occultation). These observations were
used to derive a multitude of parameters, in particular atmospheric trace gas amounts. In addition to radiance measurements solar spectral irradiances (SSIs) were measured on a daily basis.
The instrument was operating for nearly a decade, from August 2002 to April 2012. Due to the harsh space environment, it suffered from continuous optical degradation. As part of recent radiometric calibration activities
an optical (physical) model was introduced that describes the behaviour of the scanner unit of SCIAMACHY with time (Krijger et al., 2014).
This model approach accounts for optical degradation by assuming contamination layers on optical surfaces in the scanner unit. The variation in layer thicknesses of the various optical components is determined from the combination of solar measurements from different monitoring light paths available for SCIAMACHY.
In this paper, we present an optimisation of this degradation correction approach,
which in particular improves the solar spectral data.
An essential part of the modification is the use of measurements from SCIAMACHY's internal white light source (WLS) in combination with direct solar measurements.
The WLS, as an independent light source, therefore, gives an opportunity to better separate instrument variations and natural solar variability.
However, the WLS emission depends on its burning time and changes with time as well.
To use these measurements in the optimised degradation correction, the change in the WLS emission in space needs to be characterised first. The changes in the WLS with accumulated burning time
are in good agreement with detailed laboratory lamp studies by Sperling et al. (1996).
Although the optimised degradation-corrected SCIAMACHY SSIs still show some instrumental issues when compared to SSI measurements from other instruments and model reconstructions,
our study demonstrates the potential for the use of an internal WLS for degradation monitoring.
Design and Optimization of a Diffuser for a Horizontal Axis Hydrokinetic Turbine using Computational Fluid Dynamics based Surrogate Modelling
Authors: Sherbaz Salma 
Published: July 2020

Fossil fuels have remained at the backbone of the global energy portfolio. With the growth in the number of factories, population, and urbanization; the burden on fossil fuels has also been increasing. Most importantly, fossil fuels have been causing damage to the global climate since industrialization. The stated issues can only be resolved by shifting to environment friendly alternate energy options. The horizontal axis hydrokinetic turbine is considered as a viable option for renewable energy production. The aim of this project is the design and optimization of a diffuser for horizontal axis hydrokinetic turbine using computational fluid dynamics based surrogate modeling. The two-dimensional flat plate airfoil is used as a benchmark and flow around the airfoil is simulated using Ansys Fluent. Later, computational fluid dynamics analyses are carried out for baseline diffuser generated from the flat plate airfoil. The performance of this diffuser was optimized by achieving an optimum curved profile at the internal surface of the diffuser. The response surface methodology is used as a tool for optimization. A maximum velocity augmentation of 31.70% is achieved with the optimum diffuser.
Hinged multiperforator-based extended dorsalis pedis adipofascial flap for dorsal foot defects
Authors: Abd Al Moktader Magdy A. 
Published: July 2020

Background Adipofascial flaps covered with a skin graft address the challenges involved in reconstructing dorsal foot defects. The purpose of this study was to describe a large adipofascial flap based on the perforators of the dorsalis pedis artery for large foot defects.
Methods Twelve patients aged 5–18 years with large soft tissue defects of the dorsal foot due to trauma were treated with an extended dorsalis pedis adipofascial flap from May 2016 to December 2018. The flap was elevated from the non-injured half of the dorsum of the foot. Its length was increased by fascial extension from the medial or lateral foot fascia to the plantar fascia to cover the defect. All perforators of the dorsalis pedis artery were preserved to increase flap viability. The dorsalis pedis artery and its branches were kept intact.
Results The right foot was affected in 10 patients, and the left foot in two patients. All flaps survived, providing an adequate contour and durable coverage with a thin flap. Follow-up lasted up to 2 years, and patients were satisfied with the results. They were able to wear shoes. Donor-site morbidity was negligible. Two cases each of partial skin graft loss and superficial necrosis at the tip of the donor cutaneous flap occurred and were healed by a dressing.
Conclusions The hinged multiperforator-based extended dorsalis pedis adipofascial flap described herein is a suitable method for reconstructing dorsal foot defects, as it provides optimal functional and aesthetic outcomes with minimal donor site morbidity.
1er Café de bioéthique « Le citoyen et ses objets connectés : qu’advient-il de ses données? »
Authors: Boudreau LeBlanc Antoine , Masella Marie-Alexia 
Published: July 2020

Ce compte-rendu résume les échanges tenus lors du 1er Café de bioéthique de 2019, qui a porté sur le thème : « Le citoyen et ses objets connectés : qu’advient-il de ses données? » Trois experts panélistes et un public de 70 personnes ont participé à cette rencontre. La discussion a notamment précisé les avantages que peuvent avoir les objets connectés, tels qu’une autonomisation et une responsabilisation des individus, mais a aussi mis en lumière certains risques comme une hypernormativité ou encore la question d’obtention d’un consentement valide. Des pistes de solution et de réglementation ont été proposées par le public et les experts. Cette rencontre s’inscrit dans une série de trois Cafés de bioéthique tenue à Montréal et à Québec sur le sujet de l’éthique, de la santé et des données.
L’éducation au vivre ensemble en Suisse : analyse des plans d’études et enjeux de formation
Authors: Durisch Gauthier Nicole 
Published: July 2020

Cet article propose un inventaire des usages de l’expression « vivre(-)ensemble » et de son correspondant allemandZusammenleben à partir des versions modèles des deux principaux plans d’études en Suisse. Il dresse une cartographie du vivre ensemble en identifiant les parties des plans d’études dans lesquelles cette notion est mobilisée et les disciplines, objectifs et contenus auxquels elle est associée. Il propose en outre une analyse des enjeux et projets liés au vivre-ensemble d’une part pour en dégager les lignes principales et d’autre part pour en saisir des traductions locales. Enfin, l’article propose, à partir des résultats de notre recherche, une analyse de trois défis liés à l’éducation au vivre ensemble en contexte scolaire et de formation des enseignants.
Formamidinium‐Based Dion‐Jacobson Layered Hybrid Perovskites: Structural Complexity and Optoelectronic Properties
Authors: Gélvez‐Rueda María C. , Ahlawat Paramvir , Merten Lena , Jahanbakhshi Farzaneh , Mladenović Marko , Hinderhofer Alexander , Dar M. Ibrahim , Li Yang , Dučinskas Algirdas , Carlsen Brian , Tress Wolfgang , Ummadisingu Amita , Zakeeruddin Shaik M. , Schreiber Frank , Hagfeldt Anders , Rothlisberger Ursula , Grozema Ferdinand C. , Milić Jovana V. , Graetzel Michael 
Published: July 2020

AbstractLayered hybrid perovskites have emerged as a promising alternative to stabilizing hybrid organic–inorganic perovskite materials, which are predominantly based on Ruddlesden‐Popper structures. Formamidinium (FA)‐based Dion‐Jacobson perovskite analogs are developed that feature bifunctional organic spacers separating the hybrid perovskite slabs by introducing 1,4‐phenylenedimethanammonium (PDMA) organic moieties. While these materials demonstrate competitive performances as compared to other FA‐based low‐dimensional perovskite solar cells, the underlying mechanisms for this behavior remain elusive. Here, the structural complexity and optoelectronic properties of materials featuring (PDMA)FAn–1PbnI3n+1 (n = 1–3) formulations are unraveled using a combination of techniques, including X‐ray scattering measurements in conjunction with molecular dynamics simulations and density functional theory calculations. While theoretical calculations suggest that layered Dion‐Jacobson perovskite structures are more prominent with the increasing number of inorganic layers (n), this is accompanied with an increase in formation energies that render n > 2 compositions difficult to obtain, in accordance with the experimental evidence. Moreover, the underlying intermolecular interactions and their templating effects on the Dion‐Jacobson structure are elucidated, defining the optoelectronic properties. Consequently, despite the challenge to obtain phase‐pure n > 1 compositions, time‐resolved microwave conductivity measurements reveal high photoconductivities and long charge carrier lifetimes. This comprehensive analysis thereby reveals critical features for advancing layered hybrid perovskite optoelectronics.
Catechol‐Based Molecular Memory Film for Redox Linked Bioelectronics
Authors: Wu Si , Kim Eunkyoung , Chen Chen‐yu , Li Jinyang , VanArsdale Eric , Grieco Christopher , Kohler Bern , Bentley William E. , Shi Xiaowen , Payne Gregory F. 
Published: July 2020

AbstractRedox is emerging as an alternative modality for bio‐device communication. In contrast to the more familiar ionic electrical modality: (i) redox involves the flow of electrons through oxidation–reduction reactions; (ii) the aqueous medium is an “insulator” to this electron flow since free electrons do not normally exist in water; and (iii) redox states are intrinsically digital (oxidized and reduced). By exploiting these unique features, a catechol‐based molecular memory film is reported. This memory is fabricated by electrochemically grafting catechol to a chitosan–agarose polysaccharide network to generate a redox‐active but non‐conducting matrix. The redox state of the grafted catechol moieties serves as the 2‐state memory. It is shown that these redox states: can be repeatedly switched by diffusible mediators (electron shuttles); can be easily read electrically or optically; are stable for at least 2 h in the absence of energy; are sensitive to biologically relevant oxidizing and reducing contexts; and can be switched enzymatically. This catechol‐based molecular memory film is a simple circuit element for redox linked bioelectronics.
Great Enhancement of Self‐Powered Photoresponse Performance of C3H8NSi‐TiO2 NRAs/n‐Si Heterojunction by Build‐In and Build‐Out Electric Field Jointly Promoting Carrier Separation
Authors: Hou Zhidong , Li Guixia , Ling Cuicui , Wang Hongyan , Zhu Lei , Guo Tianchao , Zhang Tuo , Feng Bingxin , Cao Min , Xue Qingzhong 
Published: July 2020

AbstractA novel silane coupling agent grafting TiO2 nanorod arrays (C3H8NSi‐TiO2 NRAs)/n‐Si heterojunction is introduced. A built‐out electric field is created on the surface of TiO2 NRAs by silane coupling agent modifications, which can promote photo‐generated carriers separation so that the C3H8NSi‐TiO2 NRAs/n‐Si heterojunction shows excellent self‐powered broadband photoresponse properties. Especially under 900 nm illumination, the self‐powered device demonstrates the responsivity (R), detectivity (D*), and sensitivity (S) of ≈7.76 A W−1, ≈5.22 × 1014 Jones, and ≈1.12 × 1010 cm2 W−1, respectively. Compared with that of the unmodified TiO2 NRAs/n‐Si heterojunction, the R, D*, and S are increased by two orders of magnitude. The results are mainly ascribed to the original built‐in electric field of heterojunction and the created built‐out electric field which jointly promote carriers separation and the unconventional porous electrode which plays a crucial role in collecting holes. The DFT calculations and TRPL results indicate the formation and carriers separation capability of the built‐out electric field. This design concept can be extended to the application of other varieties of metal oxide based photoelectric devices.
Impacts of ammonia volatilization from broadcast urea on winter wheat production
Authors: Perin Vinicius , Santos Eduardo A. , Lollato Romulo , Ruiz‐Diaz Dorivar , Kluitenberg Gerard J. 
Published: July 2020

AbstractAmmonia (NH3) volatilization from broadcast urea may lead to significant N losses in winter wheat. We aimed to: (a) quantify N losses through NH3 volatilization from fields fertilized with urea and urea amended with a urease inhibitor (NBPT) under cold weather months (February–April), and (b) investigate the impact of N losses through NH3 volatilization on the winter wheat production. We employed the integrated horizontal flux (IHF) method with passive NH3 samplers to quantify NH3 volatilization at five sites in Kansas. Urea and urea + NBPT were broadcast at a rate of 60 kg N ha–1 over circular plots. We assessed the impact of NH3 losses on wheat at three sites employing different rates of urea and urea + NBPT. NH3 losses volatilization varied from 0.3 to 29.6% of total N applied. The largest N losses (>23% of applied N) occurred when urea was broadcasted to moist soils followed by a dry period. Amending urea with NBPT reduced NH3 volatilization losses by more than 20% on the campaigns with the largest N losses (>23%). However, our results showed no significant differences for wheat yield, N‐recovery and agronomic efficiency between urea and urea + NBPT treatments likely due to the reduced NH3 volatilization (<17%) where the impact on winter wheat was measured. Our results suggest that winter wheat farmers should carefully evaluate the soil surface moisture conditions before broadcasting urea to avoid potential NH3 volatilization losses even under cold conditions (average soil temperature ranging from 2.5 to 7.7 °C).
The design and manufacture of 3D‐printed adjuncts for powered air‐purifying respirators
Authors: Miles L. F. , Chuen J. , Edwards L. , Hohmann J. D. , Williams R. , Peyton P. , Grayden D. B. 
Published: July 2020

SummarySpurred in part by literature published in the immediate aftermath of the severe acute respiratory syndrome epidemic in 2003, powered air‐purifying respirators have seen increased use worldwide during the COVID‐19 pandemic. Whereas these devices provide excellent protection of the user, there is an added element of risk during doffing and cleaning of the device. An additional layer of barrier protection, in the form of a polypropylene gown, to be worn over the hood and motor belt, can be used to minimise this risk. However, the device entrains air perpendicular to the lie of the gown, resulting in the impermeable material being sucked into the air intake, and partial occlusion of flow. In this report, we describe a clinical‐academic partnership whereby a bespoke filter guard was designed to disrupt airflow and prevent gown entrainment, thereby enabling full barrier protection of both the device and user. This intervention was simple, cheap, scalable and able to be mass produced.
Trypsin Inhibitor and Urease Activity of Soybean Meal Products from Different Countries and Impact of Trypsin Inhibitor on Ileal Amino Acid Digestibility in Pig
Authors: Chen Juxing , Wedekind Karen , Escobar Jeffery , Vazquez‐Añón Mercedes 
Published: July 2020

AbstractTrypsin inhibitor (TI) and urease activity (UA) are the most relevant quality aspects of soybean meal (SBM) for monogastric animals. This study’s objective was to determine the levels of TI and UA in SBM collected from feed mills in different countries, whether TI and UA are correlated since they are both heat‐labile, and impact of TI on pig ileal amino acid digestibility. TI was 1.20–8.37 mg g−1 with 36.4% samples <3 mg g−1, UA was 0–0.311 ΔpH unit with 64.2% samples <0.05 ΔpH unit in 847 solvent‐extracted SBM samples. TI and UA results varied by countries and world areas. By country, mean TI was highest in Germany and lowest in Philippines, mean UA was highest in India and lowest in Philippines. By world areas, mean TI was highest in Latin America and lowest in North America, UA was highest in Asia and lowest in Latin America. TI and UA results vary in different soybean products, TI ranked as raw soybeans > expeller SBM > full‐fat‐extruded (FFE) SBM ≥ heat‐inactivated full‐fat (HIFF) SBM > solvent‐extracted SBM; UA ranked as raw soybeans > HIFF SBM > FFE SBM ≥ solvent‐extracted SBM ≥ expeller SBM. TI was not correlated with UA in 847 solvent‐extracted SBM, suggesting that UA may not be used as a surrogate indicator for TI. A diet contained 38% SBM with 8.78 mg g−1 TI significantly reduced apparent ileal digestibility of amino acids and crude protein by 13.3–26.0% and 23.3% points, respectively, in cannulated pigs compared to SBM with 2.51 mg g−1 TI.