bluuebunny/crossref_metadata_2025_split huggingface dataset:
A practical method utilizing multi-spectral LiDAR to aid points cloud matching in SLAM
Authors: Jiang Changhui , Chen Yuwei , Tian Wenxin , Feng Ziyi , Li Wei , Zhou Chunchen , Shao Hui , Puttonen Eetu , Hyyppä Juha 
Published: November 2020

Abstract
Light Detection and Ranging (LiDAR) sensors are popular in Simultaneous Localization and Mapping (SLAM) owing to their capability of obtaining ranging information actively. Researchers have attempted to use the intensity information that accompanies each range measurement to enhance LiDAR SLAM positioning accuracy. However, before employing LiDAR intensities in SLAM, a calibration operation is usually carried out so that the intensity is independent of the incident angle and range. The range is determined from the laser beam transmitting time. Therefore, the key to using LiDAR intensities in SLAM is to obtain the incident angle between the laser beam and target surface. In a complex environment, it is difficult to obtain the incident angle robustly. This procedure also complicates the data processing in SLAM and as a result, further application of the LiDAR intensity in SLAM is hampered. Motivated by this problem, in the present study, we propose a Hyperspectral LiDAR (HSL)-based-intensity calibration-free method to aid point cloud matching in SLAM. HSL employed in this study can obtain an eight-channel range accompanied by corresponding intensity measurements. Owing to the design of the laser, the eight-channel range and intensity were collected with the same incident angle and range. According to the laser beam radiation model, the ratio values between two randomly selected channels’ intensities at an identical target are independent of the range information and incident angle. To test the proposed method, the HSL was employed to scan a wall with different coloured papers pasted on it (white, red, yellow, pink, and green) at four distinct positions along a corridor (with an interval of 60 cm in between two consecutive positions). Then, a ratio value vector was constructed for each scan. The ratio value vectors between consecutive laser scans were employed to match the point cloud. A classic Iterative Closest Point (ICP) algorithm was employed to estimate the HSL motion using the range information from the matched point clouds. According to the test results, we found that pink and green papers were distinctive at 650, 690, and 720 nm. A ratio value vector was constructed using 650-nm spectral information against the reference channel. Furthermore, compared with the classic ICP using range information only, the proposed method that matched ratio value vectors presented an improved performance in heading angle estimation. For the best case in the field test, the proposed method enhanced the heading angle estimation by 72%, and showed an average 25.5% improvement in a featureless spatial testing environment. The results of the primary test indicated that the proposed method has the potential to aid point cloud matching in typical SLAM of real scenarios.
Joint Imaging Platform for Federated Clinical Data Analytics
Authors: Scherer Jonas , Nolden Marco , Kleesiek Jens , Metzger Jasmin , Kades Klaus , Schneider Verena , Bach Michael , Sedlaczek Oliver , Bucher Andreas M. , Vogl Thomas J. , Grünwald Frank , Kühn Jens-Peter , Hoffmann Ralf-Thorsten , Kotzerke Jörg , Bethge Oliver , Schimmöller Lars , Antoch Gerald , Müller Hans-Wilhelm , Daul Andreas , Nikolaou Konstantin , la Fougère Christian , Kunz Wolfgang G. , Ingrisch Michael , Schachtner Balthasar , Ricke Jens , Bartenstein Peter , Nensa Felix , Radbruch Alexander , Umutlu Lale , Forsting Michael , Seifert Robert , Herrmann Ken , Mayer Philipp , Kauczor Hans-Ulrich , Penzkofer Tobias , Hamm Bernd , Brenner Winfried , Kloeckner Roman , Düber Christoph , Schreckenberger Mathias , Braren Rickmer , Kaissis Georgios , Makowski Marcus , Eiber Matthias , Gafita Andrei , Trager Rupert , Weber Wolfgang A. , Neubauer Jakob , Reisert Marco , Bock Michael , Bamberg Fabian , Hennig Jürgen , Meyer Philipp Tobias , Ruf Juri , Haberkorn Uwe , Schoenberg Stefan O. , Kuder Tristan , Neher Peter , Floca Ralf , Schlemmer Heinz-Peter , Maier-Hein Klaus 
Published: November 2020

PURPOSE Image analysis is one of the most promising applications of artificial intelligence (AI) in health care, potentially improving prediction, diagnosis, and treatment of diseases. Although scientific advances in this area critically depend on the accessibility of large-volume and high-quality data, sharing data between institutions faces various ethical and legal constraints as well as organizational and technical obstacles. METHODS The Joint Imaging Platform (JIP) of the German Cancer Consortium (DKTK) addresses these issues by providing federated data analysis technology in a secure and compliant way. Using the JIP, medical image data remain in the originator institutions, but analysis and AI algorithms are shared and jointly used. Common standards and interfaces to local systems ensure permanent data sovereignty of participating institutions. RESULTS The JIP is established in the radiology and nuclear medicine departments of 10 university hospitals in Germany (DKTK partner sites). In multiple complementary use cases, we show that the platform fulfills all relevant requirements to serve as a foundation for multicenter medical imaging trials and research on large cohorts, including the harmonization and integration of data, interactive analysis, automatic analysis, federated machine learning, and extensibility and maintenance processes, which are elementary for the sustainability of such a platform. CONCLUSION The results demonstrate the feasibility of using the JIP as a federated data analytics platform in heterogeneous clinical information technology and software landscapes, solving an important bottleneck for the application of AI to large-scale clinical imaging data.
The Importance of Leptin to Reproduction
Authors: Childs Gwen V , Odle Angela K , MacNicol Melanie C , MacNicol Angus M 
Published: November 2020

AbstractA healthy nutritional state is required for all aspects of reproduction and is signaled by the adipokine leptin. Leptin acts in a relatively narrow concentration range: too much or too little will compromise fertility. The leptin signal timing is important to prepubertal development in both sexes. In the brain, leptin acts on ventral premammillary neurons which signal kisspeptin (Kiss1) neurons to stimulate gonadotropin releasing hormone (GnRH) neurons. Suppression of Kiss1 neurons occurs when agouti-related peptide neurons are activated by reduced leptin, because leptin normally suppresses these orexigenic neurons. In the pituitary, leptin stimulates production of GnRH receptors (GnRHRs) and follicle-stimulating hormone at midcycle, by activating pathways that derepress actions of the messenger ribonucleic acid translational regulatory protein Musashi. In females, rising estrogen stimulates a rise in serum leptin, which peaks at midcycle, synchronizing with nocturnal luteinizing hormone pulses. The normal range of serum leptin levels (10-20 ng/mL) along with gonadotropins and growth factors promote ovarian granulosa and theca cell functions and oocyte maturation. In males, the prepubertal rise in leptin promotes testicular development. However, a decline in leptin levels in prepubertal boys reflects inhibition of leptin secretion by rising androgens. In adult males, leptin levels are 10% to 50% of those in females, and high leptin inhibits testicular function. The obesity epidemic has elucidated leptin resistance pathways, with too much leptin in either sex leading to infertility. Under conditions of balanced nutrition, however, the secretion of leptin is timed and regulated within a narrow level range that optimizes its trophic effects.
Psychological burden of the COVID-19 pandemic and its associated factors among frontline doctors of Bangladesh: a cross-sectional study
Authors: Barua Lingkan , Zaman Muhammed Shahriar , Omi Fardina Rahman , Faruque Mithila 
Published: November 2020

Background: Frontline doctors are the most vulnerable and high-risk population to get the novel coronavirus disease 2019 (COVID-19) infection. Hence, we aimed to evaluate the anxiety, depression, sleep disturbance and fear of COVID-19 among frontline doctors of Bangladesh during the pandemic, and the associated factors for these psychological symptoms. Methods: In total, 370 frontline doctors who were involved in the treatment of suspected or confirmed COVID-19 patients during the pandemic took part in an online cross-sectional study. Recruitment was completed using convenience sampling and the data were collected after the start of community transmission of COVID-19 in the country. Anxiety and depression, sleep disturbance, and fear of COVID-19 were assessed by the Patient Health Questionnaire-4, two-item version of the Sleep Condition Indicator, and the Fear of Coronavirus-19 scale, respectively. Socio-demographic information, health service-related information, co-morbidity, and smoking history were collected for evaluating risk factors. The proportion of psychological symptoms were presented using descriptive statistics and the associated factors were identified using multinomial logistic regression analysis. Results: Of the doctors, 36.5% had anxiety, 38.4% had depression, 18.6% had insomnia, and 31.9% had fear of COVID-19. In multinomial logistic regression, inadequate resources in the workplace were found as the single most significant predictor for all psychological outcomes: anxiety and/or depression (severe, OR 3.0, p=0.01; moderate, OR 5.3, p=0.000; mild, OR 2.3, p=0.003), sleep disturbance (moderate, OR 1.9, p=0.02), and fear of COVID-19 (severe, OR 1.9, p=0.03; moderate, OR 1.8, p=0.03). Conclusions: The study demonstrated a high burden of psychological symptoms among frontline doctors of Bangladesh during the COVID-19 pandemic situation. Inadequate resources are contributing to the poor mental health of Bangladeshi doctors. The supply of sufficient resources in workplaces and mental health counseling may help to mitigate the burden of the psychological symptoms identified among the respondents..
Temporal artery temperature measurements versus bladder temperature in critically ill patients, a prospective observational study
Authors: Cox Eline G. M. , Dieperink Willem , Wiersema Renske , Doesburg Frank , van der Meulen Ingeborg C. , Paans Wolter 
Published: November 2020

Purpose
Accurate measurement of body temperature is important for the timely detection of fever or hypothermia in critically ill patients. In this prospective study, we evaluated whether the agreement between temperature measurements obtained with TAT (test method) and bladder catheter-derived temperature measurements (BT; reference method) is sufficient for clinical practice in critically ill patients.

Methods
Patients acutely admitted to the Intensive Care Unit were included. After BT was recorded TAT measurements were performed by two independent researchers (TAT1; TAT2). The agreement between TAT and BT was assessed using Bland-Altman plots. Clinical acceptable limits of agreement (LOA) were defined a priori (<0.5°C). Subgroup analysis was performed in patients receiving norepinephrine.

Results
In total, 90 critically ill patients (64 males; mean age 62 years) were included. The observed mean difference (TAT-BT; ±SD, 95% LOA) between TAT and BT was 0.12°C (-1.08°C to +1.32°C) for TAT1 and 0.14°C (-1.05°C to +1.33°C) for TAT2. 36% (TAT1) and 42% (TAT2) of all paired measurements failed to meet the acceptable LOA of 0.5°C. Subgroup analysis showed that when patients were receiving intravenous norepinephrine, the measurements of the test method deviated more from the reference method (p = NS).

Conclusion
The TAT is not sufficient for clinical practice in critically ill adults.
Clinical outcomes of Ahmed glaucoma valve implantation without fixation of a plate: The free plate technique
Authors: Lee Han Min , Park Kee Sup , Jeon Yoo Young , Kim Woo Jin , Lee Nam Ho , Kim Kyoung Nam , Kim Chang-sik 
Published: November 2020

ObjectiveThis study compared surgical outcomes between free plate Ahmed glaucoma valve (FPAGV) implantation without plate fixation and conventional Ahmed glaucoma valve (CAGV) implantation with plate fixation.MethodsA retrospective, comparative case series study. Patients with refractory glaucoma who underwent FPAGV or CAGV implantation and were followed >1 year were enrolled consecutively. We reviewed medical records, including data on postoperative intraocular pressure (IOP) and postoperative complications. The success rate and early postoperative hypertensive phase were compared between groups.ResultsA total of 74 patients with CAGV implantations and 36 patients with FPAGV implantations were studied. The average follow-up periods were 23.3 ± 2.6 months (CAGV) and 22.8 ± 2.8 months (FPAGV; p = 0.424). The surgery time was significantly shorter in the FPAGV group than in the CAGV group (42.6 ± 4.1 vs. 47.3 ± 5.4 min; p < 0.001). Postoperative IOP at 1 week and 1 month were significantly lower in the FPAGV group than in the CAGV group (11.8 ± 3.6 and 14.0 ± 5.3 mmHg vs. 18.7 ± 5.5 and 22.2 ± 5.2 mmHg; p = 0.012 and p = 0.002, respectively). An early postoperative hypertensive phase occurred in 62 eyes, and the frequency was greater in the CAGV group (50 eyes) than the FPAGV group (12 eyes; p = 0.001). There was no significant difference in postoperative complications between the two groups (p = 0.735). The success rate was 84.2% in the FPAGV group and 80.6% in the CAGV group 24 months after surgery (p = 0.367).ConclusionFPAGV implantation was associated with a shorter surgery time, without any change in the extent of IOP reduction or complication rate. This procedure may be considered a good alternative for CAGV implantation in patients with refractory glaucoma.
Challenges for Change Agents. Best Practices at the University Library of Freie Universität Berlin
Authors: Lee Martin , Riesenweber Christina 
Published: November 2020

Abstract
The authors of this article have been managing a large change project at the university library of Freie Universität Berlin since January 2019. At the time of writing this in the summer of 2020, the project is about halfway completed. With this text, we would like to give some insight into our work and the challenges we faced, thereby starting conversations with similar undertakings in the future.
Contrastive linguistic approaches as a key to dilute the stereotype of Chinese as a superhard language
Authors: 马 跃  
Published: November 2020

提 要汉语难学的说法对于汉语作为外语的初学者负面影响是显而易见的。对于非汉字文化圈的汉语学习者来说，对汉字望而生畏的现象尤为普遍。汉字，特别是汉字字形和非字母线索的发音规律，通常给人汉语难学的第一印象。因此，他们初学汉语时往往希冀通过汉语拼音替代汉字，以此来绕过汉字这一汉语学习的“重大障碍”。有些汉语教师也有意无意地顺应汉语初学者的要求，在教学过程中采用汉语拼音替代汉字以化解学生汉语难学的心理。然而，这种忽略汉字对汉语学习重要作用的学习与教学方法事实上具有很强的误导作用，由于汉语存在大量的同音字，这种回避策略常常会给畏惧汉语的学习心理带来雪上加霜的负担。只有还原汉字在汉语学习中的本来面目才有可能有效促进汉语学习，降低学生汉语难学的心理障碍。对于成人汉语学习者来说，通过对汉语和其母语（以英语为例）两种语言的文字特征进行比较分析，采用汉字领先的教学方式，还原汉语拼音与英语音标等同的辅助作用，帮助学生采用灵活的方法摸索汉字意义与发音规律，用母语的语言知识来认识、理解和解构汉语，用自己熟悉的方式观察和学习汉语，从而减少汉语难学的心理障碍。在教学实践中我们发现，采用这种积极直面汉字的初学汉语方法能够帮助学生较快接受汉字，观察还发现：较快接受汉字而且较多使用汉字的初学者的进步幅度明显高于过多依赖拼音的学习汉语者。
Paradigmatic pattern analysis
Authors: Stefanowitsch Anatol 
Published: November 2020

Abstract
The phrase Sprache ist der Schlüssel zur Integration (“language is the key to integration”) is found frequently in the discourse around immigration in the German-speaking countries. Based on a corpus-linguistic analysis of this phrase, this paper proposes the existence of a particular type of constructional idiom I refer to as ‘paradigmatic pattern’. Like a metaphorical pattern (in the sense of Metaphorical Pattern Analysis), a paradigmatic pattern establishes a correspondence between a word occurring in a particular slot of the idiom and another word more typical of that slot, contributing to a conceptual mapping between the domains instantiated by these words. Unlike in the case of metaphorical patterns, the domain evoked by the paradigmatic pattern is not the domain in which the pattern occurs in its literal meaning, but a domain evoked by a highly frequent collexeme in one of the slots. As in the case of metaphorical patterns, however, this collexeme contributes (aspects of) its meaning even when it is replaced by another word. I suggest a generalized version of Metaphorical Pattern Analysis, referred to as Paradigmatic Pattern Analysis, to deal with such expressions.
De língua de imigração a língua de estudo: caminhos para revitalização da cultura e da língua japonesa no âmbito paulista
Authors: Matsubara-Morales Leiko 
Published: November 2020

O presente trabalho tem por objetivo revisar historicamente o ensino de língua japonesa no contexto paulista de língua de minoria asiática, partindo da perspectiva de seu ensino como Língua de Herança (LH) nas comunidades de japoneses e nipo-descendentes e também seu ensino como Língua Estrangeira (LE) em escolas públicas apresentando como ela está integrada à sociedade brasileira. Para isso, o artigo faz uma breve incursão sobre as intervenções do governo japonês, apresentando sucintamente as principais atividades de instituições como a JICA - Japan International Cooperation Agency e a Fundação Japão; situa a importância do ensino de uma língua asiática de minoria, como é o caso da língua japonesa no contexto universitário, e tece sugestões para uma nova agenda de políticas educacionais considerando os efeitos da tecnologia e da globalização.
Quality Improvement Incorporating a Feedback Loop for Accurate Medication Reconciliation
Authors: Russ Christiana M. , Stone Susan , Treseler Jennifer , Vincuilla Julie , Partin Lindsay , Jones Elyse , Chu Esther , Currier Denise , Kelly Daniel P. 
Published: November 2020

OBJECTIVES:
Medication reconciliation errors on hospital admission can lead to significant patient harm. A pediatric intermediate care unit initiated a quality improvement project and aimed to reduce errors in admission medication reconciliation by 50% in 12 months.

METHODS:
From August 2017 to December 2018, a multidisciplinary team conducted a quality improvement project with plan-do-study-act methodology. Continuous data collection was achieved by reviewing medications with home caregivers within 18 hours of admission to identify errors. Cycle 1 consisted of nursing training in accurate and thorough medication history documentation. Cycle 2 was aimed at improving data collection. Cycle 3 was aimed at improving pediatric housestaff processes for medication reconciliation. In cycle 4 intervention, the reconciliation process was redesigned to incorporate the bedside nurse reviewing final medication orders with the patient’s home caregivers once the medication reconciliation process was complete. Intermittent maintenance data collection continued for 12 months thereafter.

RESULTS:
Cycle 1 and 2 interventions resulted in improvement in the medication reconciliation error rate from 9.8% to 4.7%. In cycle 2, the data collection rate improved from 61% to 80% of admissions sustained. Cycle 3 resulted in a further reduction in the medication error rate to 2.9%, which was sustained in cycle 4 and over the 12-month maintenance period. A patient’s number of home medications did not correlate with the error rate.

CONCLUSIONS:
Reductions in admission medication reconciliation errors can be achieved with staff education on medication history and process for medication reconciliation and with process redesign that incorporates active medication order review as a closed-loop communication with home caregivers.
Os desafios do tratamento multidisciplinar da dor pós-pandemia ocasionada pelo vírus Sars-CoV-2
Authors: Teixeira Lucas , Freitas Renato Leonardo de , Carvalho Leonardo Cesar 
Published: November 2020

JUSTIFICATIVA E OBJETIVOS: A Associação Internacional para o Estudo da Dor recomendou a revisão da definição de dor para "Uma experiência sensorial e emocional desagradável associada com, ou semelhante àquela associada a dano real ou potencial do tecido”. De fato, a dor é uma experiência pessoal influenciada em vários graus por fatores biológicos, psicológicos e sociais1. A pandemia provocada pela (SARS-CoV-2) expôs profissionais de saúde que não estavam preparados para os desafios sem precedentes. Muitos se concentraram em ventiladores, leitos de terapia intensiva, mas outros permaneceram na vanguarda do tratamento da dor. O objetivo deste trabalho foi apresentar uma revisão sobre o impacto da pandemia por COVID-19 no tratamento da dor, além da proposição de uma alternativa frente ao presente contexto, como a telereabilitação. CONTEÚDO: Trata-se de uma revisão integrativa realizada nas bases de dados: LILACS, Scielo, Pubmed, Scopus, Web of Science, PubCovid e bases de dados dedicadas a publicação de Preprints sobre a temática COVID-19, como Psyarxiv e Preprint MedRxiv. Na presente revisão pretendemos evidenciar os prejuízos cognitivos, emocionais e comportamentais relacionadas à dor durante a pandemia causada pela COVID-19. CONCLUSÃO: O contexto pandêmico e isolamento social pode interferir negativamente nas respostas de sensibilidade e no tratamento da dor, seja pelo aumento em eventos de dor na população, impactados pelos prejuízos sociais e psicológicos ou pela interrupção do atendimento presencial durante a pandemia. Neste ponto, recomendamos o avanço gradual na abordagem das limitações atuais do tratamento e propomos um roteiro futuro para enfrentar possíveis desafios que possam se apresentar.
Нестоличная реновация
Authors: Голубева Яна Анатольевна , Веретенников Даниил Игоревич , Коротыч Виктор Игоревич , Крутенко Любовь Викторовна , Малышев Гавриил Николаевич , Низамутдинова Гульназ Разябовна 
Published: November 2020

Крупные города России сегодня — это значительные материальные ресурсы, накопленные в недвижимости и инфраструктуре, объемы ветшания которых превосходят возможности финансирования ежегодного ремонта. Неравномерность развития страны приводит к сверхконцентрации людей и ресурсов в крупных городах и агломерациях, что, с одной стороны, усугубляет неравенство социально-экономического развития регионов, с другой — усиливает разрыв в развитии центров и периферий внутри самих крупных городов. Так, крупные города России, столкнувшиеся с массовым миграционным притоком, развиваются экстенсивно, расползаясь на периферию и оттягивая ресурсы из пределов освоенной урбанизированной территории, что приводит к деградации существующей застройки, усугублению социального и инфраструктурного неравенства. Прежде чем нас накроет волной катастрофических обрушений, разрывов сетей и других подобных проблем, следует предусмотреть новые механизмы реновации фондов, а также найти альтернативу экстенсивному развитию.
Реновация за пределами Москвы — это проблема, в рамках которой необходимо найти инструменты работы с существующими фондами без их тотального сноса. Мы в качестве базовой гипотезы принимаем, что при размещении новых объемов в границах застроенных территорий и привнесении на недосформированные территории пространственной структуры возникнут возможности развития имеющегося фонда и инфраструктур. Размещение новой застройки должно улучшать качество сложившейся среды, а не порождать градостроительные конфликты.
В рамках исследования на примере кейса Санкт-Петербурга были выделены восемь морфотипов, характерных для среды постсоветского города. Для каждого из них определены пространственные инструменты работы с застроенными территориями, предполагающие скрупулезную работу с контекстом, включающую в том числе привлечение к участию в городском развитии максимального числа собственников жилья. С помощью проектирования как исследовательского инструмента был оценен примерный емкостный ресурс освоенных урбанизированных территорий при их развитиипо предложенной компактной модели.