bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physical Biomarkers of Disease Progression: On-Chip Monitoring of Changes in Mechanobiology of Colorectal Cancer Cells
Authors: Armistead Fern J. , Gala De Pablo Julia , Gadêlha Hermes , Peyman Sally A. , Evans Stephen D. 
Published: February 2020

AbstractDisease can induce changes to subcellular components, altering cell phenotype and leading to measurable bulk-material mechanical properties. The mechanical phenotyping of single cells therefore offers many potential diagnostic applications. Cells are viscoelastic and their response to an applied stress is highly dependent on the magnitude and timescale of the actuation. Microfluidics can be used to measure cell deformability over a wide range of flow conditions, operating two distinct flow regimes (shear and inertial) which can expose subtle mechanical properties arising from subcellular components. Here, we investigate the deformability of three colorectal cancer (CRC) cell lines using a range of flow conditions. These cell lines offer a model for CRC metastatic progression; SW480 derived from primary adenocarcinoma, HT29 from a more advanced primary tumor and SW620 from lymph-node metastasis. HL60 (leukemia cells) were also studied as a model circulatory cell, offering a non-epithelial comparison. We demonstrate that microfluidic induced flow deformation can be used to robustly detect mechanical changes associated with CRC progression. We also show that single-cell multivariate analysis, utilising deformation and relaxation dynamics, offers potential to distinguish these different cell types. These results point to the benefit of multiparameter determination for improving detection and accuracy of disease stage diagnosis.
Global warming hiatus contributed weakening of the Mascarene High in the Southern Indian Ocean
Authors: P.J. Vidya , Ravichandran M. , Subeesh M. P. , Chatterjee Sourav , M. Nuncio 
Published: February 2020

AbstractThe Mascarene High (MH) is a semi-permanent subtropical high-pressure zone in the South Indian Ocean. Apart from its large influence on African and Australian weather patterns, it also helps in driving the inter-hemispheric circulation between the Indian Ocean in the south and subcontinental landmass in the north. Using observations and reanalysis products, this study for the first time investigates recent warming trend observed in the MH region during the Global Warming Hiatus (GWH) period (1998–2016). Significant positive trends are observed in sea surface temperature (SST), sea surface height (SSH) and oceanic heat content (OHC) during this period in the MH region. Mixed layer heat budget analysis reveals the dominant role of heat advection in the observed warming trend. During the GWH period, stronger zonal currents advect the warm waters from the Western Pacific (WP) towards the MH region via the Indonesian Throughflow (ITF). This warming in the MH reduces the sea level pressure therein and establishes a weak pressure gradient between the MH and the northern hemisphere landmass. This in-turn weakens the cross-equatorial winds in the western Indian Ocean.
Identification of putative biomarkers for Infantile Hemangiomas and Propranolol treatment via data integration
Authors: Gomez-Acevedo Horacio , Dai Yuemeng , Strub Graham , Shawber Carrie , Wu June K. , Richter Gresham T. 
Published: February 2020

AbstractInfantile hemangiomas (IHs) are the most common benign tumors in early childhood. They show a distinctive mechanism of tumor growth in which a rapid proliferative phase is followed by a regression phase (involution). Propranolol is an approved treatment for IHs, but its mechanism of action remains unclear. We integrated and harmonized microRNA and mRNA transcriptome data from newly generated microarray data on IHs with publicly available data on toxicological transcriptomics from propranolol exposure, and with microRNA data from IHs and propranolol exposure. We identified subsets of putative biomarkers for proliferation and involution as well as a small set of putative biomarkers for propranolol’s mechanism of action for IHs, namely EPAS1, LASP1, SLC25A23, MYO1B, and ALDH1A1. Based on our integrative data approach and confirmatory experiments, we concluded that hypoxia in IHs is regulated by EPAS1 (HIF-2α) instead of HIF-1α, and also that propranolol-induced apoptosis in endothelial cells may occur via mitochondrial stress.
Coordinated voltage/var control in a hybrid AC/DC distribution network
Authors: Qiao Feng , Ma Jin 
Published: February 2020

A hybrid AC/DC distribution network (HDN) is formed after multiple hybrid AC/DC microgrids (MGs) and distributed generators (DGs) are integrated into the distribution network. Voltage/var control (VVC) in this evolved system constitutes a big challenge to system operators as a large variety of voltage control devices with quite different control characteristics are expected to be co‐managed. This study proposes a coordinated VVC scheme to regulate voltage in an HDN by integrating power management model of hybrid AC/DC MGs into HDN's VVC model. The devices at HDN's level and those in MGs are allocated into two different models, and two models are linked via an approach called mathematical programmes with equilibrium constraints to achieve system‐wide coordination. In the proposed VVC, mechanical devices such on‐load‐tap changer (OLTC) and shunt capacitor (SC) are scheduled every 2 h to save their lifetime, while the electronically interfaced DGs and MGs are scheduled every 30 min to leverage their fast power support. Case studies on a modified IEEE 33 nodes distribution system validate that the proposed VVC can effectively coordinate MGs' power support with OLTC, SCs, and DGs, and it constitutes significant improvements on power loss reduction and voltage quality compared with traditional VVC.
Biosynthesis and characterisation of zinc oxide nanoparticles from Punica granatum (pomegranate) juice extract and its application in thin films preparation by spin‐coating method
Authors: Barzinjy Azeez Abdullah , Hamad Samir Mustafa , Esmaeel Mahera Muhsin , Aydın Semih Khurshid , Hussain Faiq Hama Saeed 
Published: February 2020

In this work, zinc oxide (ZnO) thin film has been assembled through the spin‐coating method and accumulated on the p‐type silicon (100) wafer. The ZnO nanoparticles (NPs) prepared via an entirely green procedure using Punica granatum (pomegranate) juice extract as an efficient chelating and capping agent. The coated ZnO NPs exhibited a homogeneous thin film over the silicon wafer. The crystal structure, surface morphology, alignment, and optical characteristics of ZnO thin film were studied through X‐ray diffraction, field‐emission scanning electron microscopy, EDX analysis, infrared spectroscopy, in addition to UV–vis spectra, correspondingly. The structure of the ZnO thin film was indexed as a wurtzite structure. UV–vis spectroscopy reveals that the alteration is straight bandgap energy (Eg) and it is precisely 3.41 eV. The acquired ZnO thin films conceivably utilised as a photovoltaic material. The IR absorbance spectra indicate that the ZnO NPs spin‐coated on the Si substrate improves the crystalline quality.
Angular momentum profiles of Class 0 protostellar envelopes
Authors: Gaudel M. , Maury A. J. , Belloche A. , Maret S. , André Ph. , Hennebelle P. , Galametz M. , Testi L. , Cabrit S. , Palmeirim P. , Ladjelate B. , Codella C. , Podio L. 
Published: February 2020

Context. Understanding the initial properties of star forming material and how they affect the star formation process is a key question. The infalling gas must redistribute most of its initial angular momentum inherited from prestellar cores before reaching the central stellar embryo. Disk formation has been naturally considered as a possible solution to this “angular momentum problem”. However, how the initial angular momentum of protostellar cores is distributed and evolves during the main accretion phase and the beginning of disk formation has largely remained unconstrained up to now.
Aims. In the framework of the IRAM CALYPSO survey, we obtained observations of the dense gas kinematics that we used to quantify the amount and distribution of specific angular momentum at all scales in collapsing-rotating Class 0 protostellar envelopes.
Methods. We used the high dynamic range C18O (2−1) and N2H+ (1−0) datasets to produce centroid velocity maps and probe the rotational motions in the sample of 12 envelopes from scales ~50 to ~5000 au.
Results. We identify differential rotation motions at scales ≲1600 au in 11 out of the 12 protostellar envelopes of our sample by measuring the velocity gradient along the equatorial axis, which we fit with a power-law model v ∝ rα. This suggests that coherent motions dominate the kinematics in the inner protostellar envelopes. The radial distributions of specific angular momentum in the CALYPSO sample suggest the following two distinct regimes within protostellar envelopes: the specific angular momentum decreases as j ∝ r1.6±0.2 down to ~1600 au and then tends to become relatively constant around ~6 × 10−4 km s−1 pc down to ~50 au.
Conclusions. The values of specific angular momentum measured in the inner Class 0 envelopes suggest that material directly involved in the star formation process (<1600 au) has a specific angular momentum on the same order of magnitude as what is inferred in small T-Tauri disks. Thus, disk formation appears to be a direct consequence of angular momentum conservation during the collapse. Our analysis reveals a dispersion of the directions of velocity gradients at envelope scales >1600 au, suggesting that these gradients may not be directly related to rotational motions of the envelopes. We conclude that the specific angular momentum observed at these scales could find its origin in other mechanisms, such as core-forming motions (infall, turbulence), or trace an imprint of the initial conditions for the formation of protostellar cores.
Characterizing the spatial pattern of solar supergranulation using the bispectrum
Authors: Böning Vincent G. A. , Birch Aaron C. , Gizon Laurent , Duvall Thomas L. , Schou Jesper 
Published: February 2020

Context. The spatial power spectrum of supergranulation does not fully characterize the underlying physics of turbulent convection. For example, it does not describe the non-Gaussianity in the horizontal flow divergence.
Aims. Our aim is to statistically characterize the spatial pattern of solar supergranulation beyond the power spectrum. The next-order statistic is the bispectrum. It measures correlations of three Fourier components and is related to the nonlinearities in the underlying physics. It also characterizes how a skewness in the dataset is generated by the coupling of three Fourier components.
Methods. We estimated the bispectrum of supergranular horizontal surface divergence maps that were obtained using local correlation tracking (LCT) and time-distance helioseismology (TD) from one year of data from the helioseismic and magnetic imager on-board the solar dynamics observatory starting in May 2010.
Results. We find significantly nonzero and consistent estimates for the bispectrum using LCT and TD. The strongest nonlinearity is present when the three coupling wave vectors are at the supergranular scale. These are the same wave vectors that are present in regular hexagons, which have been used in analytical studies of solar convection. At these Fourier components, the bispectrum is positive, consistent with the positive skewness in the data and consistent with supergranules preferentially consisting of outflows surrounded by a network of inflows. We use the bispectral estimates to generate synthetic divergence maps that are very similar to the data. This is done by a model that consists of a Gaussian term and a weaker quadratic nonlinear component. Using this method, we estimate the fraction of the variance in the divergence maps from the nonlinear component to be of the order of 4–6%.
Conclusions. We propose that bispectral analysis is useful for understanding the dynamics of solar turbulent convection, for example for comparing observations and numerical models of supergranular flows. This analysis may also be useful to generate synthetic flow fields.
Translation quality gained through the implementation of the iso en 17100:2015 and the usage of the blockchain
Authors: Duro Moreno Miguel 
Published: February 2020

AbstractTheiso en17100:2015 (Translation Services – Requirements for Translation Services) is a quality standard including a set of provisions (requirements and recommendations) for all the core aspects of the translation process, considered as an industrial asset. Its main (or, rather, itsonly) goal is the implementation of a series of activities deemed as necessary for the delivery of a quality translation end-product, on the assumption that a quality process leads ineluctably to a quality end-product. The standard’s provisions do not refer to what is in Spain known astraducción jurada(sworn translation). This paper addresses what the standard leaves out: a proposal for the implementation of its provisions, combined with the usage of the blockchain1and other disruptive technologies to sworn translation, by focusing on the illustrative case of Spain. It discusses the applicable regulations concerningsworn translationandsworn translation standardizationand explores the methods through which the combined application of a functional translation methodological framework, the provisions of theiso en17100:2015 standard, a standardized macrotextual pattern and a number of security devices and disruptive technologies might contribute to building a quality management system in the domain of sworn translation.
Englische Gerichtsverhandlungen in Deutschland und Europa
Authors: Dalügge-Momme Natascha 
Published: February 2020

Abstract
Time and again, the topic of “Proceedings in English at German courts’ haunts the German media. Despite the
failure of this experiment in some German cities, others keep trying again and again. This is intended to secure Germany as a
court location in the long term. Other countries in Europe, such as Belgium, the Netherlands or France, have also been toying with these
possibilities. What are the results there? Have they led to the expected securing of the place of jurisdiction? Are all those
involved in the proceedings, such as judges, public prosecutors and lawyers, any witnesses, clerks, court ushers, the office and
the interested public up to the challenge of following or conducting the proceedings in a language foreign to them? What are the
experiences?
Metaphor thoughtfully
Authors: Barnden John 
Published: February 2020

Abstract
Some Cognitive Linguistic theorizing and related
psychological experimentation points to the active use of
metaphorical, source/target relationships (mappings) in the mind
even when external metaphorical communications are absent. However,
some ramifications of this need attention. This article explores how
people might mentally add metaphor while
understanding discourse, i.e., mentally couch their understanding in
metaphorical terms not used by the discourse itself. This could even
involve giving a literal sentence a metaphorical understanding.
Metaphor addition is suggested by psychological evidence of
bidirectionality in metaphor, where there is not only the normal,
“forwards” transfer of information from source to target but also
“reverse” transfer. In a different vein, the article deepens the
author’s previous Anti-Analogy-Extension Thesis
whereby source-domain items that are not mapped into the target can
nevertheless be crucial in indirectly illuminating the target, and
therefore arguably crucial in representing it. This results in an
unusually holistic and fictionalist view of mental
representation.
Figures of speech revisited
Authors: Bierwiaczonek Bogusław 
Published: February 2020

Abstract
The aim of the paper is to add the terms and
concepts of synecdochic metonymy (syntonymy) and synecdochic
metaphor (syntaphor) to the traditional typology of figures of
speech. It is argued that the two additional terms are useful as
they cover important intermediate categories of transfers of meaning
between synecdoche, understood as vertical transfer based on various
levels of taxonomy, and two other “master tropes”, namely metonymy
and metaphor. The proposed concepts and terms may not only help
identify and designate certain borderline cases of figurative
language, but also add precision and adequacy to the analyses of
lexical polysemy. They may also contribute to a cognitive account of
catachresis.
The metonymic exploitation of descriptive, attitudinal, and
regulatory scenarios in meaning making
Authors: Ruiz de Mendoza Ibáñez Francisco José , Galera Masegosa Alicia 
Published: February 2020

Abstract
This chapter accounts for the different outcomes
resulting from the exploitation of different kinds of situational
cognitive models (scenarios). Starting from Ruiz de Mendoza and Galera’s
(2014) taxonomy of cognitive models, we take a step
further by subdividing scenarios into descriptive, attitudinal, and
regulatory types. It is our contention that the kind of scenario
involved constrains the inferential mechanisms activated at the
pragmatic levels, which are supported by metonymic activity in the
form of metonymic expansion plus metonymic reduction. How such
processes can motivate the various formal aspects of constructions
is discussed with reference to Kay and Fillmore’s (1999) well-known description of the
What’s X Doing Y? construction. This chapter
also shows the connections between Langacker’s profile-base
relations and the metonymic exploitation of the different kinds of
scenarios.
Data analysis implications of moderately eccentric gravitational waves
Authors: Moore Blake , Yunes Nicolás 
Published: February 2020

Abstract
While the expectation is that the majority of gravitational wave events observable by ground-based detectors will be emitted by compact binaries in quasi-circular orbits, the growing number of detections suggests the possibility of detecting waves from binaries with non-negligible orbital eccentricity in the near future. Several gravitational wave models incorporate the effects of small orbital eccentricities (e ≲ 0.2), but these models may not be sufficient to analyze waves from systems with moderate eccentricity. We recently developed an inspiral only gravitational wave model that faithfully accounts for eccentric corrections in the moderate eccentricity regime (e ≲ 0.8 for certain source masses) at 3rd post-Newtonian order. Here we consider the data analysis implications of this particular waveform model by producing and analyzing posteriors via Markov chain Monte Carlo methods. We find that the accuracy to which eccentricity and source masses can be measured can increase by 2 orders of magnitude with increasing eccentricity of the signal. We also find that signals with low eccentricity can be confidently identified as eccentric as soon as their eccentricity exceeds 0.008 (0.05) for low (high) mass systems, suggesting eccentric detections are likely to come first from low-mass systems. We complete our analysis by investigating the systematic (mismodeling) error inherent in our post-Newtonian model, finding that for signals with a signal-to-noise ratio of 15, the systematic error is below the statistical error for eccentricities as high as 0.8 (0.5) for low (high) mass systems. We also investigate the systematic error that arises from using a model that neglects eccentricity when the signal is truly eccentric, finding that the systematic error exceeds the statistical error in mass for eccentricities as small as 0.02. As a byproduct of this work we also present some new measures of the accuracy of our model, and investigate the efficiency of the model. We also show that the model is efficient enough to be useful for data analysis provided we are in a mass range in which an inspiral only model is valid. In the higher mass cases, this work points to the importance of developing IMR models.
Study on the Calculation of Cable Emergency Current Capacity Based on Real-time Measurement Data
Authors: Wang P Y , Xu Z F , Xu T , Li H R , Lai L R , Liu G 
Published: February 2020

Abstract
In actual operation, the cable may bear extra load due to other line faults within a certain time. This load is called the emergency Current Capacity, and this time period is called the emergency time. There are two main ways to solve the emergency Current Capacity using the thermal circuit. One is to take the surface temperature of the cable outer sheath as the boundary of the transient thermal circuit, without considering the influence of laying environment. The other is to use the environmental thermal parameters recommended by IEC standard. Since the actual environment along the cable is complex and changeable, and the environmental thermal parameters are time-varying, both methods will cause errors. In this paper, the environmental thermal parameters are calculated by using the data obtained from the real-time measurement, which is then substituted into the derived formula to obtain the emergency Current Capacity algorithm. The correctness of the algorithm is verified by comparing the results with the ones of FEA simulation and IEC. The results show that: the algorithm proposed in this paper is safe and more accurate. The effects of initial load and emergency time are also be analysed at the same time.
Power flow model with flat frequency control and load characteristic for voltage stability indices
Authors: Lomi Abraham , Krismanto Awan Uji , Yudi Limpraptono F , Widodo Kartiko Ardi , Mahmudi Ali , Faisol Ahmad 
Published: February 2020

Abstract
The growing of power systems with massive interconnection becomes more complicated for reliable and economical operation under dynamic as well as steady-state operating conditions. Therefore, it is desirable to develop techniques for evaluating the voltage stability condition with the implementation of the voltage stability index and the minimum singular value of the system. This paper proposes an approach a model of power flow incorporating the generator controls with considering load characteristics of flat frequency control (FFC) scheme in large interconnected power systems. Results on a 24-Bus EHV practical system is presented for illustration of power flow solution.
PID controller parameters enhanced founded on Artificial Fish Swarm Algorithm
Authors: Kouassi B A , Zhang Yiming , Mbyamm Kiki M J , Ouattara S 
Published: February 2020

AbstractOptimization issues are of great importance to both the industrial and scientific worlds. Artificial Fish Swarm Algorithm (AFSA) is a clever optimization algorithm founded on a behaviour inspired by the nature. The enhanced artificial fish swarm algorithm (EAFSA), settled on chaotic model, is applied to optimize the Proportional Integral Derivatives PID parameters, which increases the dynamic of the tuning mechanism and improves its fundamental behaviour. The simulation results show that this optimization algorithm gives faster response, shorter adjustment time and smaller overshoot.