bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of atrial arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy: a systematic review and meta-analysis
Authors: Rujirachun Pongprueth , Wattanachayakul Phuuwadith , Charoenngam Nipith , Winijkul Arjbordin , Ungprasert Patompong 
Published: April 2020

Background/objectives
Little is known about atrial involvement in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). Recent studies have suggested that atrial arrhythmia, including atrial fibrillation, atrial flutter (AFL), and atrial tachycardia, was common among these patients although the reported prevalence varied considerably across the studies. The current systematic review and meta-analysis was conducted with the aim of comprehensively investigating the prevalence of overall atrial arrhythmia and each atrial arrhythmia subtype in the setting of ARVC by identifying all relevant studies and combining their results together.

Methods
A comprehensive literature review was conducted by searching for published articles indexed in MEDLINE and EMBASE databases from inception through to 22 September 2019 to identify cohort studies of patients with ARVC that described the prevalence of atrial arrhythmia among the participants. The pooled prevalence across studies was calculated using a random-effect, generic inverse variance method of DerSimonian and Laird with a double arcsine transformation.

Results
A total of 16 cohort studies with 1986 patients with ARVC were included in this meta-analysis. The pooled prevalence of overall atrial arrhythmia among patients with ARVC was 17.9% [95% confidence interval (CI), 13.0–24.0%; I
2 88%], the pooled prevalence of atrial fibrillation of 12.9% (95% CI, 9.6–17.0%; I
2 78%), the pooled prevalence of AFL of 5.9% (95% CI, 3.7–9.2%; I
2 70%), and the pooled prevalence of atrial tachycardia of 7.1% (95% CI, 3.7–13.0%; I
2 49%).

Conclusion
Atrial arrhythmia is common among patients with ARVC with the pooled prevalence of approximately 18%, which is substantially higher than the reported prevalence of atrial arrhythmia in the general population.
The Macroeconomic Determinants and the Impact of Sanctions on FDI in Iran
Authors: Ghahroudi Mehdi Rasouli , Chong Li Choy 
Published: April 2020

Abstract
We examine the impact of the macroeconomic determinants of foreign direct investment inflows. We also investigate the moderating role of sanctions in FDI inflows into Iran. The results reveal that macro determinants such as infrastructure, exchange rate, inflation rate, investment return, and governance have a long-run effect on FDI inflows in Iran. Our findings also show that GDP growth rate and trade openness have no significant effect on FDI. Our results indicate that sanctions do not have a significant moderating role in the relationship between macroeconomic factors and FDI. Surprisingly, international sanctions have a positive relationship with FDI inflows in Iran. Furthermore, sanctions have a positive impact on the inflation rate and exchange rate in Iran. Finally, our findings show that sanctions have had a significant impact on Iran’s economic growth in recent years due to increasing the severity level of sanctions.
Seed productivity and variability of Scots pine (Pinus sylvestris L.) clones of Finnish origin in seed orchard in the central part of Ukraine
Authors: Neyko Ihor , Kolchanova Olena , Monarkh Veronika , Poznyakova Svitlana 
Published: April 2020

Abstract
Global climate change has mainly impacted the forest ecosystems in Europe. Today, it is not fully understood how these changes will affect the reproductive process of trees on seed orchards. The main aim of the study is to evaluate the growth, condition and reproductive function of Scots pine clones of Finnish origin after moving them to the southern direction of natural distribution area. Variability and seed productivity of 25-year-old clones of Scots pine of Finnish origin in the clonal seed orchard under climatic conditions of the central part of Ukraine (Vinnitsa region) was investigated. Grafted seedlings of Scots pine of Finnish origin were moved southward at a distance of over 1,500 km. Climatic conditions of Vinnytsia region, where the clones were displaced, differed by an increase in the mean and maximum temperatures by 3.3–3.6ºC, as well as an increase in the mean temperatures during the cold period and a rise in the minimum by 2.1–2.3ºC. The climate in the seed orchard location was characterized by the most significant increase in the mean temperatures in April and May (5.3–5.8ºC), which greatly influenced the intensity of the formation of microstrobili and macrostrobili. The ratio of precipitation to the amount of temperatures decreased more than twice. Analysis of the grafted trees’ vitality of Finnish origin and seed progeny of the local population, estimation of their intensity (height, diameter), state (category of the state) and reproductive processes (intensity of formation of microstrobili and cones) was carried out on the clonal seed orchard. In conditions of climate change, most of the clones of Finnish origin were characterized by a higher intensity of flowering compared to the local population. Some clones of Finnish origin (E80 and E729) dominated the local population by the seed yield. According to a comprehensive analysis of vitality, the intensity of growth and reproductive capacity, the best clones of Finnish origin were E80, E1883 and E2254. Low adaptive ability was noted in the clones E2312, K634 and K801. According to the research results, it was found that changes in climatic conditions did not significantly affect the vitality, development and condition of the clones. There was observed intensification of the formation of microstrobili and cones. Seed viability and quality of Scots pine of Finnish origin obtained on seed orchards located in the southern conditions requires further research.
Does time of protective procedure and genotype of chamomile affect yield?
Authors: Kowalska Jolanta , Seidler-Łożykowska Katarzyna , Jakubowska Magdalena , Drożdżyński Dariusz 
Published: April 2020

Summary

Objective: Chamomile plants (Chamomilla recutita L. Rausch) are often attacked by pests, which usually cause the decrease of raw material yield and its quality. The objects of field trial were two chamomile cultivars: Złoty Łan (4n) and Promyk (2n) cultivated under organic regime. The aim of this study was to evaluate of impact of the spinosad treatment and its time of application on two chamomile cultivars: cv. Promyk – 2n and cv. Złoty Łan – 4n exposed to insect pests.

Methods: The first treatment with spinosad as a preventative control (P) was performed in the early phase of plant development (seven leaves). Intervention (I) treatment was made in green bud phase. In both terms of observation insect pests were observed and collected. In each spraying application of 0.06 g of spinosad per 1 liter of water was used.

Results: Spinosad was able to limit the number of pest population and finally increased yielding of the treated cultivars as compared to the untreated plants. Time of spinosad application for cv. Złoty Łan plants was not statistically siginificant, although was more effective for the preventative treatment of cv. Promyk in the increasing of the plant biomass (283.8 g · m−2) and seed (32 g · m−2) yields than intervention.

Conclusion: Protection treatment with spinosad might be recommended in chamomile cultivation and it is more effective than intervention in diploid cultivar which begin blooming earlier than tetraploid. Essential oil content was not related with protection treatment for diploid cultivar, although intervention in tetraploid cultivar caused higher content of oil.
Detection of circulating tumour cells in the breast cancer using CytoTrack system
Authors: Bogacz Anna , Wolek Marlena , Górska Aleksandra , Leporowska Ewa , Procyk Danuta , Kolenda Piotr , Litwiniuk Maria , Uzar Izabela , Gryszczyńska Agnieszka , Łowicki Zdzisław , Czerny Bogusław 
Published: April 2020

Summary

Introduction: Plants are a rich source of healing substances. Cancer is a leading cause of death worldwide while breast cancer is the most common cancer among women. Circulating tumour cells (CTCs) are potential founder cells for metastasis. Therefore, their assessment may be used for monitoring of treatment as well as detecting cancer metastatis. Hence, it is suggested that the number of CTCs may be a valuable tumour biomarker during therapy.

Objective: The purpose of this study was to detect CTCs in breast cancer and to validate the method of assessment of CTC count using CytoTrack CT11 technology.

Methods: MCF-7 cells were sorted by a FACSARIA flow cytometer from blood samples derived from patients who have not been diagnosed with cancer. Identification and quantitative assessment of MCF-7 cells in blood samples were determined by flow sorting. Then, blood samples containing MCF-7 cells or without MCF-7 were scanned with the use of an automated fluorescence scanning microscope.

Results: In in vitro model analysing the glass CytoDisc™ with stained MCF-7 cells, we noted the correlation between the amount of observed tumour cells and expected number of tumour cells. Moreover, coefficient of variation in case of the recovery rate of the assumed number of MCF-7 cells was 30%, 17%, 18% and 15%, respectively.

Conclusion: Our study suggest that CTCs could be predictive factor in patients with metastatic cancer especially in breast cancer.
Antiprotozoal investigation of three Combretum species (Combretaceae) growing in Nigeria
Authors: Ogbole Omonike O. , Akinleye Toluwanimi E. , Segun Peter A. , Fasinu Pius S. 
Published: April 2020

Summary

Introduction:
Combretum species has been utilised for decades in African indigenous medical practices for the treatment of several parasitic infections.

Objectives: This study aims at investigating the antileishmanial, antiplasmodial and antitrypanosomal properties of Combretum racemosum, Combretum platypterum and Combretum zenkeri.

Methods: The leaf extracts of the plants were screened against two strains of Plasmodium falciparum using Plasmodium lactate dehydrogenase (pLDH) assay; promastigote and amastigote forms of Leishmania donovani; and Trypanosoma brucei brucei using Alamar Blue assay. Cytotoxicity screening were also carried out on African green monkey kidney cell line (Vero) and human monocytic leukemia (THP-1) cell lines.

Results:
C. racemosum was active against chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of P. falciparum (IC50 of 25.6 and 26.7 µg/ml, respectively) and exerted significant antiprotozoal activities against T. brucei brucei (IC50 = 18.44 µg/ml). The extract of C. platypterum displayed a slightly lower antiplasmodial activity when compared to C. racemosum, while C. zenkeri was inactive against the parasites. In addition, the extracts failed to display significant inhibitory activity on the proliferation of L. donovani.

Conclusions: This study supports the ethnomedicinal use of C. racemosum. Further research needs to be carried out to identify the antiprotozoal compounds in C. racemosum, as this could be explored for possible antiprotozoal drug development.
Leadership Coaching across Cultures
Authors: Chmielecki Michał , Contreras-Loera Marcela 
Published: April 2020

Abstract

Objective: The discussion presented in this paper focuses on the practical coaching techniques premised on lasting principles of human learning; principles that are crucial to coaching relationships of all kinds. The principles involved tap into years of psychological research and practice (Kanfer & Goldstein, 1991; Mahoney, 1991) that focuses on issues that prompt changes in people, the important factors that fosters relationships and the ways of getting people to give up their regular actions for a new set.

Methodology: The article’s research is based on extensive literature analysis.

Findings: The research was not able to identify the specifics of what people value in different cultures; however, it captures the major active ingredients in learning endeavor, without taking culture into consideration.

Value Added: The article discusses 3 main types of challenges that leadership coaches find across the globe and offers guidelines to handle them

Recommendations: Future papers on that topic research should include both qualitative and quantitative research findings.
Teachers’ Conceptions of Assessment for Learning: What are the Implications for Children?
Authors: O’Shea Amanda 
Published: April 2020

Abstract
This paper describes a multi-case study which linked conceptions and practices of assessment for learning to developing learner autonomy within UK primary mathematics classrooms. The project explored the use of assessment for learning in mathematics lessons with Year 5 (9–10 years old) children and their teachers. Four cases were studied in depth to understand how conceptions and practices impacted upon autonomy and control for teachers and learners. A typology of assessment for learning in mathematics is proposed, along with what this might mean for both teachers and learners in terms of the balance between control and autonomy. One case in particular, that of teacher Alex, is highlighted as it exemplified the expert teacher through the conceptions and use of assessment for learning, which led to the children becoming expert learners of mathematics. The class ethos was one of value for personal autonomy. Responsibility and control of learning was a shared endeavour within a community of learners. Community in this respect was broadened to include the environment and resources within the classroom and so demonstrated learners working within an expert classroom. This article was developed from a paper first presented at the ICME 13 conference (O’Shea, 2016).
A Case Study Exploring the Impact of Valuing Practices and Emotional Labour on the Well-being of one Senior Leader
Authors: Barrow Joanne , O’Shea Amanda 
Published: April 2020

Abstract
This article examines the theoretical frameworks of valuing practices and emotional labour in relation to a managerial position within a Higher Education setting. Positive aspects of these frameworks are explored along with challenges that can be faced by those striving to implement these management strategies in their practice. The methods used provided both qualitative and quantitative data via key vocabulary and phrases related to valuing practice and emotional labour as identified through observation and semi-structured interview, and the frequency of key vocabulary being used. The study takes the form of a case study. There is one participant who is a Higher Education employee working in a senior managerial position, line managing a small number of staff. This individual was chosen in order to explore their use of valuing practices and emotional labour within his management approaches. Analysis of the data identified a higher range of vocabulary relating to valuing practices than emotional labour. Overall conclusions are that valuing practices support the well-being of both leaders and staff through the motivation that is inspired by knowledgeable praise. Yet the possible risks of valuing practices should also be considered, such as non-engagement of staff. Emotional labour risks the well-being of leaders more so due to a difference in organisation and individual believes and ethos.
Language does not modulate fake news credibility, but emotion does
Authors: Fernández-López María , Perea Manuel 
Published: April 2020

Abstract
The proliferation of fake news in internet requires understanding which factors modulate their credibility and take actions to limit their impact. A number of recent studies have shown an effect of the foreign language when making decisions: reading in a foreign language engages a more rational, analytic mode of thinking (Costa et al., 2014, Cognition). This analytic mode of processing may lead to a decrease in the credibility of fake news. Here we conducted two experiments to examine whether fake news stories presented to university students were more credible in the native language than in a foreign language. Bayesian analyses in both experiments offered support for the hypothesis that the credibility of fake news is not modulated by language. Critically, Experiment 2 also showed a strong direct relationship between credibility and negative emotionality regardless of language. This pattern suggests that the driving force behind the engagement in an automatic thinking mode when reading fake news is not language (native vs. foreign) but emotionality.
Inconsistencies between mental fatigue measures under compensatory control theories
Authors: Muñoz-de-Escalona Enrique , Cañas José J. , Noriega Paulo 
Published: April 2020

Abstract
Mental fatigue has traditionally been defined as a condition of reduced cognitive efficiency and performance, accompanied by a subjective feeling of fatigue. Even though we could expect to find associations between the three defining characteristic of mental fatigue (performance impairment, physiological deactivation and subjective fatigue), research has shown that the emergence of inconsistencies between measures is more frequent than one might expect: people proved capable of maintaining adequate performance levels even after having declared themselves fatigued. This could be explained under the compensatory control mechanism models, which state that humans are able to provide additional resources under demanding conditions, but only at the expense of psychophysiological cost and subjective fatigue. We tested this explanation by manipulating task complexity and time performing a simulated air-traffic control task. We collected psychophysiological, performance and subjective data. A decrease in pupil size was seen in the low-aircraft-density condition, while pupil size remained constant in the high-aircraft-density condition. Participants’ task performance was optimal in both conditions, though they showed an increase in subjective feelings of fatigue, especially in the high-complexity task condition. Thus, complexity seemed to trigger compensatory mechanisms, which reallocated extra resources that physiologically activated participants in order to deal with a higher complexity task, whereas subjective fatigue could be acting as a signal to the organism of impending resource depletion. Our findings support compensatory control theories and offer an explanation of inconsistencies between fatigue measures. Further research on compensatory mechanisms is needed to enable better management of fatigue effects to prevent work-related accidents.
IgG/IgA-pemphigus — extremely rare blistering autoimmune diseases
Authors: Karamova Arfenya E. , Znamenskaya Lyudmila F. , Chikin Vadim V. , Mihina Viktoria A. , Nefedova Maria A. 
Published: April 2020

Purpose. To present a clinical case of IgG/IgA pemphigus in a 32-year-old woman.
Material and methods. Clinical and laboratory examinations were performed to diagnose the disease: cytological examination of an impression smear from the bottom of the erosion, histological examination of a skin biopsy sample from the lesion, immunofluorescent examination of a biopsy sample of visually accessible unaffected skin.
Results. Clinical manifestations of the disease were similar to Duhring's dermatitis herpetiformis, morphological ones to pemphigus vulgaris, but immunofluorescent examination of the skin biopsy sample in equal measure revealed deposits of both IgG and IgA in the epidermis, which allowed to determine a diagnosis of IgG/IgA pemphigus. Dapsone therapy at a dose of 100 mg per day led to a significant improvement in the patient's condition.
Conclusion. Diagnosis of bullous dermatoses requires immunofluorescent examination of a biopsy sample of visually accessible unaffected skin. Dapsone was an effective medication for the patient with IgG/IgA pemphigus.
Incompetência istmocervical: cerclagem de emergência versus conduta expectante
Authors: Rego Sabrina Cabral , Martins Adelaide Gomes , Mesquita Francisca Amanda de Souza 
Published: April 2020

Objetivo:Descrever sobre incompetência istmocervical:cerclagem de emergência versus conduta expectante.Revisão bibliográfica:Estudos anteriores indicaram que existe benefício quanto ao tratamento cirúrgico, uma vez que gestantes tem maior período de latência até o parto, maior idade gestacional ao nascimento e diminuição de taxa de prematuridade. Mulheres acometidas à cerclagem cervical para o tratamento da incompetência istmo cervical (IIC)continuama possuir risco elevado para prematuridade. Já na cerclagem de emergência têm-se maiores taxas de prematuridade e de maiores complicações se correlacionada a cerclagem profilática ou terapêutica.. E, de maneira geral, a cerclagem aumenta o risco de infecções puerperais (6%), internações hospitalares e de realização de cesarianas.Considerações finaisO diagnóstico de incompetência cervical embasa, primariamente, na história clínica, podendo ser efetuado antes ou durante a gestação. A cerclagem é a conduta com maior aceitabilidade de acordo com a literatura, devido aos índices de sobrevivência fetal e das gestantes portadoras de IIC no período que antecede o parto e após passar pelo tratamento e procedimento cirúrgico.
COVID 19: Effect on leading pharmaceutical stocks listed with NSE
Authors: Aravind M  , Manojkrishnan C G  
Published: April 2020

The purpose of this study is to examine how Covid 19 outbreak has affected leading pharmaceutical stocks listed with the National Stock Exchange of India. We have selected ten leading pharmaceutical companies listed with NSE, and the selection was purely based on the market capitalization of the companies. The general hypothecation of this study was the pharmaceutical stocks will move against the general market trend (contrarian effect). The study period was classified in to pre-crisis period and Covid 19 crisis period. The data consists of 123 daily price observations of the selected 10 pharmaceutical companies. The period of study is ranging from 3rd September 2019 to 28th February 2020. The results reported that momentum effect is persisting with pharmaceutical stocks as the pharmaceutical stocks are moving in accordance with the general benchmarking index. Only two companies, namely Aurobindo Pharma Ltd and Lupin Ltd reported with varied return trend during the study period. This study also signifies that companies like Sun Pharma, Cipla, Glenmark with strong brand reputation were seems to be sustaining in the crisis period in spite of the general falling market trend. This paper is strongly urge the need for backward integration and enhanced research and development activities to Indian Pharmaceutical sector for ensuring their sustainable long-run operations.
Analysis of The Effect Of The Addition of Fly Ash and Petrsoil on The Soil Shear Strength of The Swamp Area
Authors: . Indrayani Indrayani , Herius Andi , Saputra Daiyan , Fadi Al Muhammad 
Published: April 2020

The existence of irrigation canals greatly supports the production of rice produced, where irrigation channels will be equipped with embankment to protect irrigation channels. Existing soil must certainly be able to withstand shear strength to withstand embankment, while the soil in the South Sumatra region, especially the swamp area has a low shear power so it cannot hold back the shear strength from the embankment. For this reason, it is necessary to research the shear strength of the soil in the swamp area by adding fly ash and petrasoil in order to get the effect of increasing the value of the soil shear strength in the swamp area. The tests consists of the seive analysis, index properties, atterberg limits, soil compaction, and shear strength testing, based on SNI and ASTM. Mixed variations consist of 5, namely: (i) soil + petrasoil; (ii) soil + 10% fly ash + petrasoil; (iii) soil + 15% fly ash + petrasoil; (iv) soil + 20% fly ash + petrasoil; (v) soil + 20% fly ash; all variations without ripening. The test results are obtained that addition of 10% fly ash + petrasoil could be increase the soil cohesion value that is 21.56 Kpa, while the variation of the addition of 20% fly ash + water was obtained the highest value of the shear angle, that is 32.31 Kpa.