bluuebunny/crossref_metadata_2025_split huggingface dataset:
History of coarrays and SPMD parallelism in Fortran
Authors: Reid John , Long Bill , Steidel Jon 
Published: June 2020

The coarray programming model is an expression of the Single-Program-Multiple-Data (SPMD) programming model through the simple device of adding a codimension to the Fortran language. A data object declared with a codimension is a coarray object. Codimensions express the idea that some objects are located in local memory while others are located in remote memory. Coarray syntax obeys most of the same rules for normal array syntax. It is familiar to the Fortran programmer so the use of coarray syntax is natural and intuitive. Although the basic idea is quite simple, inserting it into the language definition turned out to be difficult.
In addition, the process was complicated by rapidly changing hardware and heated arguments over whether parallelism should be supported best as an interface to language-independent libraries, as a set of directives superimposed on languages, or as a set of specific extensions to existing languages.
In this paper, we review both the early history of coarrays and also their development into a part of Fortran 2008 and eventually into a larger part of Fortran 2018. Coarrays have been used, for example, in weather forecasting and in neural networks and deep learning.
A history of the Groovy programming language
Authors: King Paul 
Published: June 2020

This paper describes the history of the Groovy programming language. At the time of Groovy’s inception, Java was a dominant programming language with a wealth of useful libraries. Despite this, it was perceived by some to be evolving slowing and to have shortcomings for scripting, rapid prototyping and when trying to write minimalistic code. Other languages seemed to be innovating faster than Java and, while overcoming some of Java’s shortcomings, used syntax that was less familiar to Java developers. Integration with Java libraries was also non-optimal.
Groovy was created as a complementary language to Java—its dynamic counterpart. It would look and feel like Java but focus on extensibility and rapid innovation. Groovy would borrow ideas from dynamic languages like Ruby, Python and Smalltalk where needed to provide compelling JVM solutions for some of Java’s shortcomings.
Groovy supported innovation through its runtime and compile-time metaprogramming capabilities. It supported simple operator overloading, had a flexible grammar and was extensible. These characteristics made it suitable for growing the language to have new commands (verbs) and properties (nouns) specific to a particular domain, a so called Domain Specific Language (DSL). While still intrinsically linked with Java, over time Groovy has evolved from a niche dynamic scripting language into a compelling mainstream language.
After many years as a principally dynamically-typed language, a static nature was added to Groovy. Code could be statically type checked or when dynamic features weren’t needed, they could be turned off entirely for Java-like performance. A number of nuances to the static nature came about to support the style of coding used by Groovy developers.

Many choices made by Groovy in its design, later appeared in other languages (Swift, C#, Kotlin, Ceylon, PHP, Ruby, Coffeescript, Scala, Frege, TypeScript and Java itself). This includes Groovy’s dangling closure, Groovy builders, null-safe navigation, the Elvis operator, ranges, the spaceship operator, and flow typing. For most languages, we don’t know to what extent Groovy played a part in their choices. We do know that Kotlin took inspiration from Groovy’s dangling closures, builder concept, default
it
parameter for closures, templates and interpolated strings, null-safe navigation and the Elvis operator.

The leadership, governance and sponsorship arrangements of Groovy have evolved over time, but Groovy has always been a successful highly collaborative open source project driven more by the needs of the community than by a vision of a particular company or person.
A history of MATLAB
Authors: Moler Cleve , Little Jack 
Published: June 2020

The first MATLAB (the name is short for “Matrix Laboratory”) was not a programming language. Written in Fortran in the late 1970s, it was a simple interactive matrix calculator built on top of about a dozen subroutines from the LINPACK and EISPACK matrix software libraries. There were only 71 reserved words and built-in functions. It could be extended only by modifying the Fortran source code and recompiling it.
The programming language appeared in 1984 when MATLAB became a commercial product. The calculator was reimplemented in C and significantly enhanced with the addition of user functions, toolboxes, and graphics. It was available initially on the IBM PC and clones; versions for Unix workstations and the Apple Macintosh soon followed.
In addition to the matrix functions from the calculator, the 1984 MATLAB included fast Fourier transforms (FFT). The Control System Toolbox appeared in 1985 and the Signal Processing Toolbox in 1987. Built-in support for the numerical solution of ordinary differential equations also appeared in 1987.
The first significant new data structure, the sparse matrix, was introduced in 1992. The Image Processing Toolbox and the Symbolic Math Toolbox were both introduced in 1993.
Several new data types and data structures, including single precision floating point, various integer and logical types, cell arrays, structures, and objects were introduced in the late 1990s.
Enhancements to the MATLAB computing environment have dominated development in recent years. Included are extensions to the desktop, major enhancements to the object and graphics systems, support for parallel computing and GPUs, and the “Live Editor”, which combines programs, descriptive text, output and graphics into a single interactive, formatted document.
Today there are over 60 Toolboxes, many programmed in the MATLAB language, providing extended capabilities in specialized technical fields.
Study of association of varicose veins and inflammation by inflammatory markers
Authors: Tiwary Satyendra K , Kumar Anoop , Mishra Shiv Prakash , Kumar Puneet , Khanna Ajay K 
Published: June 2020

Objective In varicose veins, increased levels of inflammatory markers are indicators of endothelial damage and increased procoagulant activity. These findings support the assumption that the constitution of blood in varicose veins differs from that of systemic blood. The purpose of the study was a correlative study of blood constituents in varicose veins and peripheral veins (normal vein) in same individual with varicose vein which was done by comparing the level of concentration of interleukin-6, fibrinogen, haemoglobin from blood of varicose veins and normal peripheral vein (antecubital vein). Method Using citrated plasma samples withdrawn from arms and legs of same patient and plasma obtained by centrifugation of citrated venous blood at 5000 r/min for 10 min was used for correlation. Serum concentration of interleukin-6 and fibrinogen were determined by human enzyme-linked immunosorbent assay Kit for both interleukin-6 and fibrinogen, which is based on the standard sandwich enzyme-linked immunosorbent assay technology. This assay employs a monoclonal antibody specific for human interleukin-6 coated on a 96-well plate. Result Expressed as median (interquartile range) in pg/mL, leg samples from patient having varicose vein has significantly increased interleukin-6 in cases as compared to controls ( p value of <0.001). Leg samples from patient having varicose vein has significantly increased fibrinogen concentration than their arm samples ( p value of <0.001). Concentration of haemoglobin significantly increased in leg samples as compared to blood withdrawn from arms ( p value of 0.012). Conclusion Blood withdrawn from the site of varicose vein appears to have significantly increased concentration of interleukin-6, fibrinogen and haemoglobin when compared to same patient’s antecubital blood sample supporting the hypothesis that inflammation is increased in tissues drained by varicose vein.
Slightly elevated international normalized ratio predicts bleeding episodes in patients treated with direct oral anticoagulants
Authors: Bhardwaj Priya , Petersen Louise Breum , Binko Tomas Sorm , Petersen Jan Roland , Fornitz Gitte Gleerup 
Published: June 2020

Introduction Patients treated with direct oral anticoagulants (DOACs) are at increased bleeding risk. It is therefore of increasing interest to identify predictors of bleeding episodes to increase safety during treatment with DOACs. Methods This retrospective cohort study systematically reviewed medical records of 235 patients treated with either apixaban, rivaroxaban or dabigatran for non-valvular atrial fibrillation or venous thromboembolism and collected data on the international normalized ratio (INR) and all bleeding episodes. Results INR ≥ 1.5 was significantly associated with increased risk of minor and major bleeding events in patients treated with direct factor Xa inhibitors. This association was not present in patients treated with dabigatran. However, a high negative predictive value was identified for INR < 1.5 for all drugs. The relative risks of bleeding episodes in patients with INR ≥ 1.5 and INR < 1.5 were 5.1 and 0.20, respectively. Conclusions Our results demonstrate a strong correlation between INR and risk of bleeding episodes during DOAC treatment. INR < 1.5 was a strong negative predictor for low bleeding risk independent of indication or choice of drug, and INR ≥ 1.5 was associated with increased risk of bleeding episodes in patients treated with direct factor Xa-inhibitors.
Comparison of cryptococcal meningitis in HIV-negative patients with and without lung infections
Authors: Yang Ming , Cheng Lin , Sun Fengjun , Liu Fu , Feng Wei , Yao Pu , Weng Bangbi , Xia Peiyuan 
Published: June 2020

Objective To investigate the clinical features and outcomes of cryptococcal meningitis (CM) in HIV-negative patients with and without lung infections. Methods We retrospectively reviewed the medical records of HIV-negative patients with CM admitted to two university hospitals in Southwest China over the past 5 years. Results Seventy-one patients were included, of whom 35 (49.3%) had lung disease. Compared with patients without lung infection, CM patients with lung infection tended to be male and younger (≤30 years), experienced more fever, less vomiting and fewer central nervous system symptoms; more often had low white blood cell (WBC) counts (<20 × 106/L), and fewer often had ethmoid sinusitis, maxillary sinusitis, paranasal sinusitis, and otitis media. Cryptococcus neoformans isolates from these patients were sensitive to itraconazole, voriconazole, fluconazole, and amphotericin B but resistant to flucytosine. CM patients with lung infection had higher mortality at discharge compared with patients without lung infection (8.6% vs. 0%). Multivariable analyses showed that a WBC count <20 × 106/L was significantly associated with poor treatment outcome (odds ratio 0.01, 95% confidence interval 0–0.83). Conclusion HIV-negative CM patients with lung infections tended to be male and younger. Fever, fewer central nervous system symptoms, and WBC counts <20 × 106/L were characteristic of this patient group.
Pleural Effusions Following Liver Transplantation: A Single-Center Experience
Authors: Lui Justin K. , Spaho Lidia , Hakimian Shahrad , Devine Michael , Bui Rosa , Touray Sunkaru , Holzwanger Erik , Patel Boskey , Ellis Daniel , Fridlyand Svetlana , Ogunsua Adedotun A. , Mahboub Paria , Daly Jennifer S. , Bozorgzadeh Adel , Kopec Scott E. 
Published: June 2020

Introduction: This was a single-center retrospective study to evaluate incidence, prognosis, and risk factors in patients with postoperative pleural effusions, a common pulmonary complication following liver transplantation. Methods: A retrospective review was performed on 374 liver transplantation cases through a database within the timeframe of January 1, 2009 through December 31, 2015. Demographics, pulmonary and cardiac function testing, laboratory studies, intraoperative transfusion/infusion volumes, postoperative management, and outcomes were analyzed. Results: In the immediate postoperative period, 189 (50.5%) developed pleural effusions following liver transplantation of which 145 (76.7%) resolved within 3 months. Those who developed pleural effusions demonstrated a lower fibrinogen (149.6 ± 66.3 mg/dL vs 178.4 ± 87.3 mg/dL; P = .009), total protein (5.8 ± 1.0 mg/dL vs 6.1 ± 1.2 mg/dL; P = .04), and hemoglobin (9.8 ± 1.8 mg/dL vs 10.3 ± 1.9 mg/dL; P = .004). There was not a statistically significant difference in 1-year all-cause mortality and in-hospital mortality between liver transplant recipients with and without pleural effusions. Liver transplant recipients who developed pleural effusions had a longer hospital length of stay (16.4 ± 10.9 days vs 14.0 ± 16.5 days; P = .1), but the differences were not statistically significant. However, there was a significant difference in tracheostomy rates (11.6% vs 5.4%; P = .03) in recipients who developed pleural effusions compared to recipients who did not. Conclusions: In summary, pleural effusions are common after liver transplantation and are associated with increased morbidity. Pre- and intraoperative risk factors can offer both predictive and prognostic value for post-transplantation pleural effusions. Further prospective studies will be needed to further evaluate the relevance of these findings to limit instances of postoperative pleural effusions.
Modified Tension-Slide Technique for Endoscopy-Assisted Flexor Hallucis Longus Tendon Transfer
Authors: Lucar-Lopez Gustavo , Ballester-Alomar Manel , Jimenez-Obach Albert , Navarro-Cano Ester , Villamizar Maria Angelica , Guevara-Noriega Kerbi Alejandro 
Published: June 2020

The rupture of the Achilles tendon (AT) usually occurs in high-caliber athletes, but low-demand patients are also are risk, mainly if they are under corticoids or quinolones. The diagnosis of the AT rupture is usually neglected, and this could result in a worse prognosis for the patient if not treated in an appropriate time. For these patients or for those with high surgical risk, an option of minimally invasive surgery remains attractive. Classical techniques consist of direct repair or augmentation with the tendon of the flexor hallucis longus as well as nonanatomical tendon transfers which can generate issues with the donor site. We present a pioneering technique that is analogous to that used for the surgical treatment of distal rupture of the biceps tendon, which consist of a transfer technique of flexor hallucis longus by extracortical fixation interference screw associated to a direct tendon reinsertion performed through a bone tunnel on the superior and posterior aspect of the calcaneus using an extracortical drilling system and an interference screw within the calcaneal tunnel. The arthroscopic approach may be technically challenging, and a high-level of arthroscopic skills are required to complete the procedure but after a learning curve it represents a feasible a safe technique. Levels of Evidence:Therapeutic, Level IX: Evidence from opinion of authorities and/or reports of expert committee
Vascular imaging of the spine in the US Medicare population: Catheter and MR angiography volumes from 2004 to 2016
Authors: Atsina Kofi-Buaku , Cox Mougnyan , Sedora Roman Neda I , Pukenas Bryan , Parker Laurence , Levin David C , Hurst Robert W 
Published: June 2020

Aims The purpose of our study was to analyze utilization trends and physician specialty distribution in spinal catheter angiography and magnetic resonance angiography in the Medicare fee-for-service population. Methods Data from the CMS Physician/Supplier Procedure Summary Master Files for 2004 to 2016 were used for this study. The Current Procedural Terminology version 4 codes for spinal magnetic resonance angiography (72159) and spinal catheter angiography (75705) were used to analyze the volumes of these procedures. Using Medicare’s 108 specialty code, we compared procedure volumes among physician specialties. Data analysis was performed using SAS version 9.3 for Windows. Results The volume of spinal catheter angiography performed was 4758 in 2004, peaked at 6869 in 2012, and dropped to 6656 in 2016. Overall, the volume of spinal catheter angiography increased by 40% from 2004 to 2016. Radiologists performed the majority of these procedures (3736 or 56.1%) in 2016, followed by neurosurgeons (2456 or 36.9%), and neurologists (346 or 5.2%). The spinal magnetic resonance angiography volume fluctuated between 0 and 1 from 2004 to 2009, then precipitously increased to 40 in 2010, peaked at 133 in 2011, and declined to 81 in 2016. The volume of spinal magnetic resonance angiography procedures increased by 8000% from 2004 to 2016, with radiologists performing the majority of them. Conclusion Our results show that spinal catheter angiography volumes continue to rise in the Medicare fee-for-service population, and are largely performed by radiologists, neurosurgeons, and neurologists. Although spinal magnetic resonance angiography volumes have started to increase, they comprise only a small fraction of studies performed for vascular evaluation of the spine.
Controversies with nonoperative management for adolescent idiopathic scoliosis: Study from the APSS Scoliosis Focus Group
Authors: Cheung Jason Pui Yin , Cheung Prudence Wing Hang , Shigematsu Hideki , Takahashi Shinji , Kwan Mun Keong , Chan Chris Yin Wei , Chiu Chee Kidd , Sakai Daisuke ,   APSS Scoliosis Focus Group
Published: June 2020

Purpose: To determine consensus among Asia-Pacific surgeons regarding nonoperative management for adolescent idiopathic scoliosis (AIS). Methods: An online REDCap questionnaire was circulated to surgeons in the Asia-Pacific region during the period of July 2019 to September 2019 to inquire about various components of nonoperative treatment for AIS. Aspects under study included access to screening, when MRIs were obtained, quality-of-life assessments used, role of scoliosis-specific exercises, bracing criteria, type of brace used, maturity parameters used, brace wear regimen, follow-up criteria, and how braces were weaned. Comparisons were made between middle–high income and low-income countries, and experience with nonoperative treatment. Results: A total of 103 responses were collected. About half (52.4%) of the responders had scoliosis screening programs and were particularly situated in middle–high income countries. Up to 34% obtained MRIs for all cases, while most would obtain MRIs for neurological problems. The brace criteria were highly variable and was usually based on menarche status (74.7%), age (59%), and Risser staging (92.8%). Up to 52.4% of surgeons elected to brace patients with large curves before offering surgery. Only 28% of responders utilized CAD-CAM techniques for brace fabrication and most (76.8%) still utilized negative molds. There were no standardized criteria for brace weaning. Conclusion: There are highly variable practices related to nonoperative treatment for AIS and may be related to availability of resources in certain countries. Relative consensus was achieved for when MRI should be obtained and an acceptable brace compliance should be more than 16 hours a day.
A Novel Scoring Instrument to Assess Donor Site Morbidity After Anterior Cruciate Ligament Reconstruction With a Patellar Tendon Autograft at 2-Year Follow-up Using Contemporary Graft-Harvesting Techniques
Authors: Hacken Brittney A. , Keyt Lucas K. , Leland Devin P. , LaPrade Matthew D. , Camp Christopher L. , Levy Bruce A. , Stuart Michael J. , Krych Aaron J. 
Published: June 2020

Background: Donor site morbidity after anterior cruciate ligament (ACL) reconstruction with a bone–patellar tendon–bone (BTB) autograft is clinically significant, but evidence with contemporary techniques is lacking. Purpose: To (1) evaluate donor site morbidity at a single institution using modern techniques of BTB autograft harvest at 2-year follow-up, (2) develop a 10-question donor site morbidity instrument, and (3) compare this instrument against traditional outcome tools. Study Design: Case series; Level of evidence, 4. Methods: We analyzed the 2-year follow-up outcomes of 200 consecutive patients who underwent ACL reconstruction with a BTB autograft performed by 2 surgeons at a single institution. The surgical technique utilized modern and consistent BTB autograft harvest, including graft sizing, patellar tendon and peritenon closure, and patellar and tibial donor site bone grafting. There were 187 patients included, with 13 patients undergoing revision ACL reconstruction excluded. An original 10-question scoring instrument evaluating donor site morbidity was administered to each patient (score, 0-100) and compared against each patient’s International Knee Documentation Committee (IKDC) and Lysholm scores. Results: Overall, 13.9% of patients were noted to have anterior knee pain with activity at 2-year follow-up. Moreover, 3.7% of patients reported an inability to kneel on hard surfaces but had no problems on soft surfaces; 5.9% of patients reported mild discomfort but were able to kneel on all surfaces. Additionally, 75.4% of patients had a perfect (100/100) donor site morbidity score. The mean donor site morbidity score at 2-year follow-up was 98.3 ± 3.4. There was a very strong correlation between the IKDC and Lysholm scores but only a strong and moderate correlation when the donor site morbidity score was compared with the IKDC and Lysholm scores, respectively. Conclusion: Donor site morbidity after ACL reconstruction with a BTB autograft was less frequent than reported in the existing literature. Some patients developed anterior knee pain; therefore, an informed discussion is advised. IKDC and Lysholm scores may not capture donor site symptoms after surgery. The 10-question donor site morbidity instrument may provide a more accurate assessment.