bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proteína C reactiva, síndrome metabólico y riesgo cardiovascular en la población costarricense nacida entre 1945 y 1955.
Authors: Aguilar Fernández Eduardo , Carballo Alfaro Ana Maricela 
Published: May 2020

Resumen
Introducción: Varios estudios han mencionado que existe relación entre la proteína C reactiva (PCR) y el síndrome metabólico (SM) y que esta proteína es un factor de riesgo de enfermedad cardiovascular. Objetivo: Se estudió la relación entre la PCR y el SM en la población costarricense. Métodos: Se consideraron personas nacidas en Costa Rica entre 1945 y 1955 (n = 2273). La definición del SM fue una adaptación de los criterios establecidos por la American Heart Association and National Heart, Lung and Blood Institute. Resultados: La prevalencia del SM aumenta conforme incrementan los niveles de PCR (p < 0,001) y esta prevalencia fue mayor en las mujeres (p < 0,001). La PCR se asoció en forma independiente y positiva con la circunferencia de la cintura y negativa con el colesterol HDL (C-HDL). La asociación más fuerte fue con la circunferencia de la cintura (probabilidad de superioridad (PSup) de 67,8). Después de ajustar por edad, sexo, zona de residencia, tabaquismo y consumo de bebidas alcohólicas, las personas con niveles de PCR ubicados en el cuarto cuartil tienen mayor riesgo de presentar SM en comparación con las que muestran niveles de PCR ubicados en el primer cuartil. Por otro lado, el riesgo cardiovascular fue más alto en personas con altos niveles de PCR. Conclusiones: La PCR está asociada con el SM en las personas costarricenses nacidas entre 1945 y 1955. Otros estudios son necesarios para establecer el papel de la PCR en el desarrollo del SM y eventos cardiovasculares entre la población costarricense.
Construcción de un banco de pruebas de medidores de flujo para el laboratorio de mecánica de fluidos de la Universidad Francisco de Paula Santander Ocaña
Authors: García-León Ricardo Andrés , Flórez-Solano Eder Norberto , Guerrero-Gómez Gustavo 
Published: May 2020

En la academia es importante que el estudiante realice un complemento entre la teoría y la práctica para reforzar conocimientos que hagan que la compresión del concepto sea mucho más rápida, para un tema particular, se tiene la necesidad de que el estudiante mediante la construcción de un laboratorio diferencie los medidores de los fluidos para presión y caudal. Es por esto que este proyecto tuvo como objetivo principal estudiar el efecto, funcionamiento y las aplicaciones tecnológicas de algunos medidores de flujo, como el tubo Venturi, La Tobera y la placa de Orificio, los cuales su invención data de los años 1.800 después de Cristo. La construcción del sistema de medidores de flujo se construyó en fundición de aluminio, soportado por una estructura metálica hecha en tubería cuadrada, dotado de tubería de Policloruro de Vinilo y tubería de aluminio, accesorios (Codos, uniones, machos, hembras, reducción 2 pulgadas a 1 pulgada) y una válvula que permite la conexión de una bomba centrifuga individual, permitiendo así realizar medición de caudal de un fluido para este caso se trabajara con agua, por medio de tres elementos de medida diferentes mencionados anteriormente, los datos obtenidos de los medidores se pueden contrarrestar con el dato arrojado por un Rotámetro de escala 4 – 35 Lt/min, para el registro de las presiones se instalaron cinco manómetros con rangos de 0 a 30 psi que a su vez sirven para el análisis de la relación caudal vs presión.
In search of markers useful for evaluation of graft patency - molecular analysis of ‘muscle system process’ for internal thoracic artery and saphenous vein conduits
Authors: Kałużna Sandra , Nawrocki Mariusz J. , Jopek Karol , Hutchings Greg , Perek Bartłomiej , Jemielity Marek , Kempisty Bartosz , Malińska Agnieszka , Mozdziak Paul , Nowicki Michał 
Published: May 2020

Abstract
Coronary artery bypass graft (CABG) is the surgical method most commonly used to treat coronary artery disease (CAD). The vessels that are used in CABG are usually the internal thoracic artery (ITA) and the saphenous vein (SV). Transplant patency is one of the most important factors affecting transplant success. In this study, we used an expressive microarray method, approved by RT-qPCR, for transcriptome analysis of arterial and venous grafts. In the search for potential molecular factors, we analyzed gene ontologies of different expression based on the muscular system. Among interesting groups, we distinguished muscle cell proliferation, muscle contraction, muscle system process, regulation of smooth muscle cell proliferation and smooth muscle cell proliferation. The highest increase in gene expression was observed in: ACTN2, RBPMS2, NR4A3, KCNA5, while the smallest decrease in expression was shown by the P2RX1, KCNH2, DES and MYOT genes. Particularly noteworthy are the ACTN2 and NR4A3 genes, which can have a significant impact on vascular patency. ACTN2 is a gene that can affect the formation of atherosclerotic plaques, while NR4A3 occurs in 4 of the 5 ontological groups discussed and can affect the inflammatory process in the blood vessel. To summarize, the presented study provided valuable insight into the molecular aspects characterizing the vessels used in CABG, and in particular identified genes that may be the target for further studies on duct patency.

Running title: CABG grafts’ molecular analysis of ‘muscle system process’
The Performance of Seven Molecular Methods for the Detection of PRRSV
Authors: Milićević Vesna , Kureljušić Branislav , Veljović Ljubiša , Valčić Miroslav , Stević Nataša , Savić Božidar , Radojičić Sonja 
Published: May 2020

Abstract
Porcine Reproductive and Respiratory Syndrome is a viral disease of swine characterized by reproductive failure of breeding animals and respiratory disorders in all categories. The first PRRS case in Serbia was recorded in 2001 after illegal import of boar semen. PRRS is economically the most important disease due to significant direct and indirect losses. Today, for routine diagnosis of PRRS in infected herds serological methods (ELISA) and molecular methods are used. Although modern diagnostic techniques are very robust, exceptional diversity of the viral strains is often the obstacle for an accurate diagnosis. To estimate the performance of seven different methods for PRRSV genome detection, twenty samples were used. However, none of the methods was able to detect all PRRSV strains. The best sensitivity was obtained by combining two methods. Until today, there is no absolutely accurate test which enables the detection of all circulating strains.
Characteristics of African Swine Fever Virus Isolated from Domestic Pigs and Wild Boars in the Russian Federation and South Ossetia
Authors: Vlasov Mikhail , Imatdinov Almaz , Titov Ilya , Vasković Nikola , Lyska Valentina , Sevskikh Timofey , Sybgatullova Adylia , Pivova Elena , Morgunov Sergey , Balyshev Vladimir 
Published: May 2020

Abstract
The article presents the results of a comparative study of the biological, molecular and genetic characteristics of African swine fever virus (ASFV) isolates, obtained from domestic pigs and wild boars in the Russian Federation and South Ossetia from 2016 to 2018. The studied isolates caused the death of pigs manifesting, as a rule, signs of an acute or subacute form of the disease when using various methods of infection including intramuscular, direct contact, intranasal and oral routes. The virus was hemadsorbing, belonging to serotype 8 and genotype II, and accumulated in the blood with a titer of 6.5 to 7.5 lg HAU50/cm3. The ASFV isolates circulating in the central region of Russia were found to have an insertion of 10 base pairs in the intergenic region I73R/I329L. However, the ASFV isolated in the Irkutsk region and South Ossetia, as well as Georgia 2007/1 (FR682468.1), lacked this insertion.
The Effects of a Phytogenic Additive on the Histomorphometric Characteristics of the Intestines in Weaned Pigs with a Subclinical Natural Infection with Lawsonia intracellularis
Authors: Drašković Vladimir , Stanimirović Zoran , Glišić Milica , Bošnjak-Neumuller Jasna , Teodorović Radislava , Teodorović Vlado , Kukolj Vladimir 
Published: May 2020

Abstract
Proliferative enteropathy, also known as proliferative ileitis, is considered to be one of the most economically important diseases in pig production worldwide. The estimated losses per affected growing pig usually range from US $1 to $5. The disease is caused by Lawsonia intracellularis, a Gram-negative, obligately intracellular bacterium. Control of the disease can be achieved with the use of vaccines or antibiotics. Recently there has been an increase in the efforts in the control of certain pathologies of the digestive system with phytogenic additives. The aim of this work was to assess the effects of a phytogenic additive on the histomorphometric characteristics of the intestines in weaned pigs with a subclinical infection with L. intracellularis acquired spontaneously. Histomorphometry analysis showed that crypt depth was significantly shorter (P<0.05), and the villus-height-to-crypt-depth ratio (P<0.05) significantly greater in the treatment group than the control. This improvement in the histological parameters of the intestine, considered to be indicators of its health, proved the positive effect of the tested additive on the digestive system in pigs.
Achievements in Micromagnetic Techniques of Steel Plastic Stage Evaluation
Authors: de Campos M. F. 
Published: May 2020

Abstract
The investigation of plastic deformation and residual stress by non-destructive methods is a subject of large relevance for the industry. In this article, the difference between plastic and elastic deformation is discussed, as well as their effects on magnetic measurements, as hysteresis curve and Magnetic Barkhausen Noise. The residual stress data can be obtained with magnetic measurements and also by the hole drilling method and x-ray diffraction measurements. The residual stress level obtained by these three different methods is different, because these three techniques evaluate the sample in different depths. Effects of crystallographic texture on residual stress are also discussed. The magnetoelastic term should be included in micromagnetic methods for residual stress evaluation. It is discussed how the micromagnetic energy Hamiltonian should be expressed in order to evaluate elastic deformation. Plastic deformation can be accounted in micromagnetic models as a term that increases the coercive field in soft magnetic materials as the steels are.
Effect of Sprint Training Exercise, Shuttle Run and Prevention on Base Softball Running Speed Among High School Students
Authors: Fathoni Amirudin , Rachman Hari Amirullah 
Published: May 2020

Summary
This study aims to determine the differences and to achieve better effect in the sprint training, shuttle run and agility on base of running speed of athletes softball. This study uses an experimental method with a 2×2 factorial design. Participants in this research were 42 male athletes (mean age = 16.88; SD = 1.31), Indonesian high school students. The instruments of this study were the base running test and reactive agility testing protocols. Analysis of the data is analysis of variance (ANOVA) of two pathways at a significant level α = 0.05. The results of the study are as follows: exercise sprint training give better effect to the results of base running extracurricular softball, as evidenced by the value of p = 0.036 < 0.05. Participants who have high agility level give a better effect than participants who have low agility level on the results of softball extracurricular base running, as evidenced by the value of p = 0,000 < 0.05. There is no interaction between the training model and agility on the results of softball extracurricular base running, which is evident from the value of p = 0.634 > 0.05. This research contributes to the field of softball sports, especially in creating an appropriate training program to increase the speed of base running in male students by using sprint training so that results are more effective.
The Level of Community Cohesiveness Under Psychological Pressure and Control Center for Emerging Football Players U17
Authors: Benrabah Kheiredine , Bennadja Mohamed , Fayçal Kharoubi Mohamed 
Published: May 2020

Summary
The objective of this study is to know the level the group cohesiveness and the type of relationship between it and the psychological pressure and control center for emerging footballers under the 17 years. The descriptive approach of the study was based on a sample of 70 young footballers between the ages of 15 – 17 years of the professional Algerian championship who are still studying. The measurement of cohesiveness of the group, consisting of 34 phrases divided into four dimensions, was used on 5 dimensions, and on the scale of the center control the internal and external consists of 20 phrases. We found an average level of group cohesiveness in all dimensions and in the total score of the group cohesiveness scale with mean and standard deviation estimated at (118.5 ± 13.13), high level of psychological stress and total degree of psychological stress with mean and standard deviation of 163.38 ± 10.67). The average level in the remote control center and high in the external control center, there is a statistically significant correlation between group cohesiveness and psychological stress, and a statistically significant correlation between the cohesiveness of the group and both the internal control center and the external control center. The psychological pressures negatively affect the cohesiveness of the group while the control center with its both sides the internal and external does not affect the cohesiveness of the group.
Explosive Strength of Lower Limbs in 10 – 12 Years Old Athletes of Individual Sports
Authors: Leütterová Daniela , Tomková Petra , Dzugas Dalibor , Kačúr Peter , Gonzalez Pablo Prieto 
Published: May 2020

Summary
The aim of the study was to determine the levels of lower limb explosive strength of girls in different sport specialization. The sample consisted of 24 girls in aerobic gymnastics (n = 12) and athletic (n = 12) aged 10 to 12 years. To assess the levels of girls’ lower limbs explosive strength, we administered the following tests: countermovement jump test, countermovement jump with free arms test, squat jump test, 10-seconds repetitive jumping test. Testing sessions took place in September 2019. To obtain data about the levels of lower limbs explosive strength, we recorded step height (cm) and duration of the flight phase (s). Data about the lower limbs explosive strength were collected using the Optogait system for optical detection. We applied basic statistical characteristics, namely Student’s t-test and multivariate linear regression. There were no significant differences between girls in aerobic gymnastics and athletics. We recorded better test results in the group of girl’s athletes in the countermovement jump, countermovement jump with free arms and squat jump. In the group of girl’s involved in aerobic gymnastics, we recorded better results in the 10-second repetitive vertical jumping and vertical jump strength. According to the collected data, we may conclude that the training process of the selected girls in terms of explosive strength development is significantly different. Girls involved in aerobic gymnastics showed a higher level of performance in the 10-second vertical jump, which results from the structure of sport specificity.
The Effect of Training Methods and Eye-Foot Coordination on Dribbling Abilities in Students Aged 12 – 13 Years
Authors: Armando David , Rahman Hari Amirullah 
Published: May 2020

Summary
The purpose of this study is to examine: (1) the difference in the effect of the method of dribbling sprinting and sprint interval training on the ability of dribbling; (2) the difference in influence between high-eye coordination and low-foot coordination on the ability of dribbling; and (3) the interaction between training methods and eye-foot coordination on dribbling skills. Participants in this study were 37 soccer students aged 12 – 13 years (M = 12.38; SD = 0.49). This research method is an experiment with a 2×2 factorial design. The instrument for measuring ankle coordination is the Soccer Wall Test and for measuring the ability of dribbling is the Short Dribbling Test. The data analysis technique used is two-way ANOVA at the significance level α = 0.05. The results of the study are as follows. (1) There is a significant difference in effect between the method of acceleration dribbling and interval running training on dribbling ability, as evidenced by the value of F = 14,032; p value = 0.002 < 0.05. (2) There is a significant difference in the effect of high eye-foot coordination ability and low-foot eye coordination on dribbling ability, as evidenced by the value of F = 27,685; p value = 0,000 <0.05. (3) There is a significant interaction between the training methods (acceleration and interval running dribbling exercises) and eye-foot coordination (high and low) on the dribbling ability of students aged 12-13 years, as evidenced by the value of F = 21,780 and the p value = 0,000 <0.05.
Comparison between Commercial and Nano NPK in Presence of Nano Zeolite on Sage Plant Yield and its Components under Water Stress
Authors: Mahmoud Abdel Wahab M. , Swaefy Hend M. 
Published: May 2020

Abstract
The lucrative approach of nanotechnology and it´s utilizing in the agricultural sector is prospective. Based on this fact a field trial was done through 2018 and 2019 seasons to scrutinize the consequence of nano N, P and K elements application individual or in combination and nano zeolite loaded nitrogen or not on a sage plant grown under water stress compared to the commercial NPK fertilisers at new reclaimed land. Nano NPK elements were prepared from their precursor as potassium persulfate (K2S2O8), calcium phosphate (Ca (H2PO4)2·H2O) and salt NH4NO3, urea (CO (NH2)2), while nano zeolite was hydrothermally synthesized. Water stress was applied via drip irrigation with 15 days intervals. The data revealed that, nanofertilisers and nano-zeolites had a superior effects on the plant itself under stress conditions with concern on nano-zeolite loaded nitrogen and nano-NPK mixture as well which boosted vegetative growth (plant height, branches number, yield fresh weight, health index, herb fresh and dry weight, leaf area and oil yield), also improved photosynthetic rate, stomatal conductance, CO2 concentration, water use efficiency and relative water content. The chemical composition (plant pigments, total carbohydrates, total phenolic, tannin, total flavonoids, oil constituents, macro and micro-elements) with indigenous hormones (gibberellic acid GA3 and abscisic acid ABA) and antioxidant enzymes (peroxidase and superoxide dismutase) were also positively affected. The outcomes of current study emphasis global warning about chemical fertilisers pollution, particularly in new reclaimed areas and safety production of medicinal and aromatic plants.
Molecular-Genetic Diagnostics of Angelman Syndrome – The Bulgarian Experience
Authors: Georgieva B. , Atemin S. , Todorova A. , Todorov T. , Miteva A. , Avdjieva-Tzavella D. , Mitev V. 
Published: May 2020

Abstract

Objective: The aim of the study was to determine the molecular mechanisms of mutagenesis in Bulgarian patients with Angelman syndrome (AS). AS is a severe neurodevelopmental disorder caused by loss of expression in brain of the maternally inherited UBE3A gene as a result of various 15q11.2-q13 alterations.

Material and Methods: In total 24 patients (11 boys, 13 girls) from 22 unrelated families with suspected clinical diagnosis AS were analysed. We used methylation specific PCR, multiplex ligation-dependent probe amplification, methylation sensitive MLPA, and direct sequencing of the UBE3A gene.

Results: In 9 families (41%) pathogenic mutations were detected, which confirmed the clinical diagnosis on а molecular-genetic level. In 4 (44%) of these families we found 15q11-q13 region deletion with breakpoints BP1-BP3 or BP2-BP3. In 1 (11%) of the families we found imprinting defect: deletion of the AS-SRO regulatory region (part of the PWS-AS imprinting center). In 1 (11%) of the families we detected a rare finding – paternal uniparental disomy of chromosome 15. In 3 (33%) of the families diff erent point mutations in the UBE3A gene were detected: two novel missence mutations c.488T > C; p.Leu163Ser and c.1832A > T; p.Gln611Leu, and one known frameshift mutation c.2576_2579delAAGA; p.Lys859Argfs*4.

Conclusion: The obtained results helped us to develop a systematic diagnostic algorithm in order to provide proper diagnosis for the patients with AS. Combining excellent knowledge of the molecular mechanisms of mutagenesis and proper molecular-genetic testing approaches is a cornerstone in the management of AS patients, ensuring AS families would receive both adequate genetic counseling and prophylaxis of the disease in the future.
Fungal Peritonitis Due to Gastroduodenal Perforation: Diagnostic and Treatment Challenges
Authors: Tzoneva D. , Masljankov S. , Sokolov M. , Marteva-Proevska Y. , Velinov T. 
Published: May 2020

Abstract
The gastrointestinal tract perforation is one of the leading causes of acute abdomen. Mycotic infections have become a significant clinical problem over the last few decades. Despite the advance in diagnostics and treatment of patients with fungal peritonitis, the mortality remains high.

Objective. The objective of the study was to determine the type and incidence of causative pathogens of acute peritonitis in patients with gastroduodenal perforation, and to estimate the impact of microbial flora on the disease outcome.

Materials and methods. We performed a retrospective study among 83 adult patients with acute peritonitis due to gastroduodenal perforation treated at our centre.

Results. A total of 40 mycotic agents were isolated in 39 of the abdominal samples. The primary mycotic isolates were Candida albicans (52.5%) and C. glabrata (64.3%); C. krusei (14.3%) and C. tropicalis (7.1%) predominated among non-albicans Candida species (35.0%). The most common bacterial agents were Escherichia coli (24.0%) and Enterococcus spp. (24.0%). 77.1% of all enrolled patients survived, and 19 of them deceased due to sepsis and multiple organ dysfunction syndrome.

Conclusion. Candida albicans is the most common mycotic pathogen in patients with acute peritonitis due to gastroduodenal perforation. It is obligatory to examine the peritoneal fluid samples for bacterial and fungal pathogens with determination of their antimicrobial susceptibility profile. Timely initiation of adequate treatment and multidisciplinary approach is crucial for the outcome of patients with fungal peritonitis.
Digital Determination of Curvature of Root Canals of Extracted Teeth
Authors: Kosturkov D. , Radeva E. , Uzunov T. 
Published: May 2020

Abstract

Introduction: Determination of the curvature of root canals at present is accomplished by complicated or expensive methods. Therefore, there is a need to develop a new digital method by which this curvature can be determined quickly, easily and accurately.

The aim of this in-vitro study is to determine the angles of curvature of the root canals of extracted teeth by comparing a new digital method of measurement with an established digital method.

Material and Methods: Forty-eight (48) root canals of extracted teeth were studied to achieve the goal. In all roots, curvature is measured by three methods: Method 1 – new digital photographic method and special Software (Screen Protractor); Method 2 – a new digital radiography method and special software (Screen Protractor); Method 3 – approved method, digital by X-ray and special Software (Durr dental).

Results: The mean degrees of the measured curvature of the root canals in all three groups are similar and are about 22°. There are no statistically significant differences between them (p > 0.05).

Conclusion: This shows that the new digital photographic and x-ray methods for measuring root curvature can accurately determine the curve angle for extracted teeth.