bluuebunny/crossref_metadata_2025_split huggingface dataset:
<b>O AMPARO JURÍDICO PARA A CONSTRUÇÃO DE UM AMBIENTE DE INOVAÇÃO</b>: seus reflexos no poder informacional na área de telecomunicações em missão crítica de órgão de segurança pública
Authors: Assumpção Luciano Castilho , Minghelli Marcelo 
Published: March 2020

O administrador público somente pode agir conforme a lei prever sua atuação pelo princípio da legalidade. Neste sentido, o novo amparo jurídico pode fornecer os pontos necessários para a formação de ambientes de inovação, com a participação do Estado, representado por um órgão de segurança pública, a Academia e a indústria de equipamentos de telecomunicações em missão crítica, como radiocomunicadores empregados pelo órgão para a manutenção do poder informacional durante operações policiais. O objetivo do trabalho é analisar a possibilidade de construção de um ambiente de inovação para a área de telecomunicações em missão crítica de um órgão de segurança pública, considerando o amparo jurídico que permita a atuação do Estado. Trata-se de uma pesquisa de natureza aplicada em uma abordagem qualitativa, utilizando de técnicas de Estudo de Caso através de levantamento de informações em campo e pesquisa bibliográfica. Pretende-se apontar os requisitos jurídicos necessários possibilitando a construção de um ambiente de inovação para a área de telecomunicações em missão crítica em um órgão de segurança pública para utilizá-los como instrumentos de exercício de poder informacional nas fases ostensivas de operações policiais e em atividades de vigilância e patrulhamento de fronteiras.Palavras-chave: Inovação. Estado. Poder informacional. Informação. Leis.
Nutritional Composition and Sensory Quality of Packaged Ofe-Owerri: A Major Traditional Soup in Nigeria
Authors: Oyewale Mary B. , Seidu Kudirat T. , Ogunbusola Eunice M. , Osundahunsi Oluwatooyin F. , Ogunwa Tomisin H. , Akele Olatunbosun , Adejoro Damola O. 
Published: March 2020

Background:
Ofe-Owerri is an expensive traditional soup in Nigeria, prepared using Oha
(Pterocarpus soyauxi), Ukazi (Gnetum africanum), Uziza (Piper guineense) and cocoyam (Colocasia
esculanta) as the major vegetables. The soup is highly celebrated for its traditional therapeutic and
nutritional potentials.

Objective:
In this study, we assessed the proximate and mineral components, sensory and microbial
qualities of the Ofe-Owerri soup in a cooked and packaged form. Antioxidant status and phytoconstituents
of the major vegetables of the soup were also determined.

Methods:
Established methods were used as previously reported in the literature.

Results:
Calcium was the most concentrated mineral, whereas lead was absent. High moisture
(63.45%), crude protein (14.60%) and fat (13.27%) were found in the soup. The major ingredients
(vegetables) used to prepare Ofe-Owerri contain phytochemicals such as phenolic compounds and
saponins, and showed potent antioxidant activity in various in vitro models, with uziza displaying the
highest scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. The vegetables
exhibit reductive capacity against oxidants, and chelation of metallic free radicals. There was no significant
difference (p≤0.05) in the sensory parameters of Ofe-Owerri soup kept frozen in foil and
plastic containers, respectively, for 21 days.

Conclusion:
This study showed that Ofe-Owerri is a good dietary source of nutrients and possesses
phytoconstituents with potential beneficial health effects. When properly packaged, the soup can be
stored safely for up to three weeks.
Direct At-Sea Observations of Elephant Seals (Mirounga spp.) to Help Interpret Digital Bio-logging Data
Authors: van den Hoff John , Thalmann Sam 
Published: March 2020

Background:
A key short-fall with animal-borne bio-logging instruments, which collect digital time-series data regarding the foraging behaviours of cryptic marine mammal species, is validating those data against in situ behaviours.

Objective:
To collate direct observations of elephant seal feeding behaviour to help interpret foraging behaviours inferred from Time-Depth Recorder (TDR) data.

Methods:
Direct observations of elephant seal foraging behaviour were collated from the published literature using a search of the world-wide-web. Those observations were supplemented with an unpublished record.

Results:
Two deep-sea video recordings and six surface sightings of elephant seals ingesting prey were collated. Each observation either supported or suggested an alternative to behaviours derived from digital time-depth profiles. The tendency for elephant seals to surface following the capture of large prey suggests precipitous drops in stomach temperature at the sea-surface, which have been recorded and interpreted as drinking events, more likely represent the ingestion of large prey items.

Conclusion:
Direct observations of marine mammal foraging behaviours are rare, yet they provide a means to continuously evaluate and interpret outcomes of bio-logging instruments.
A DECADE OF EXPERIENCE IN APPLICATION OF TRANSMYOCARDIAL LASER REVASCULARIZATION IN COMBINATION WITH AORTOCORONARY SHUNTING
Authors: Krnchoyan A. V. , Lyashenko S. A. , Starovoitenko A. G. , Dyuzhikova A. V. , Gasparyan R. A. , Poddubny A. V. , Dyuzhikov A. А. 
Published: March 2020

Objective: to study the security and the effect of transmyocardial laser revascularization in combination with aortocoronary shunting in patience with diffuse coronary artery disease.Materials and methods: the study compared the results of surgical treatment in patients with diffuse distal coronary artery disease in the period from 2007 to 2013. Patients were divided into two groups, the first group consisted of patients who underwent CABG in combination with TMLR (n-60), the second group includes patients who underwent isolated CABG (n-46). According to the initial demographic data and comorbidity, the groups were not significantly different from each other. Subsequent observation (on average 7, 5±0, 9 years) included rating of survival and return of angina. Results: remote mortality during the observation period in the first group was 7, 6 % (n = 4), and in the second group — 18, 9 % (n = 7). In both groups the functional class of angina pectoris significantly decreased, however, in the first group this tendency was more expressed (exertional angina I EF in the CABG + TMLR group have 54 (90 %) patients, in the second group — 33 (71,7 %), p = 0,02. Conclusions: transmyocardial laser revascularization in combination with aortocoronary shunting in high-risk patients with diffuse atherosclerotic lesions of the coronary arteries contributed to an increase in exercise tolerance, reduced symptoms, and provided an acceptable quality of life in the long term.
An Innovative Electronic Health Toolkit (Our Whole Lives for Chronic Pain) to Reduce Chronic Pain in Patients With Health Disparities: Open Clinical Trial
Authors: Gardiner Paula , D'Amico Salvatore , Luo Man , Haas Niina 
Published: March 2020

Background
Chronic pain affects millions of Americans. Our Whole Lives, an electronic health (eHealth) toolkit for Chronic Pain (Our Whole Lives for Chronic Pain [OWLCP]), is a mind-body chronic pain management platform that teaches self-management strategies to reduce pain impact and pain medication use.

Objective
The primary goal of this study was to evaluate the feasibility of OWLCP in reducing pain impact and pain-related outcomes.

Methods
We conducted a pre-post clinical study (2 cohorts) to assess the feasibility of OWLCP usage among low-income patients with chronic pain. Outcome data, collected at baseline and 9 weeks, included Patient-Reported Outcomes Measurement Information System (PROMIS-29), pain self-efficacy, and pain medication use. In the statistical analysis, we used descriptive statistics, logistic regression, linear regression, and qualitative methods.

Results
Among the enrolled 43 participants, the average age was 50 years, (39/43) 91% were female, (16/43) 37% were black, and (7/43) 16% were Hispanic. From baseline to follow-up, the PROMIS measures showed a reduction in depression (P=.02), pain interference (P=.003), and average pain impact score (P=.007). Pain self-efficacy increased ((P<.001), whereas opioid use had a 13% reduction (P=.03).

Conclusions
The eHealth chronic pain management platform, OWLCP, is a potential tool to reduce the impact of chronic pain for low-income racially diverse populations.
Influence of Community and Culture in the Ethical Allocation of Scarce Medical Resources in a Pandemic Situation: Deliberative Democracy Study
Authors: Schoch-Spana Monica , Brunson Emily K , Gwon Howard , Regenberg Alan , Toner Eric S , Daugherty-Biddison Elizabeth L 
Published: March 2020

BackgroundStark gaps exist between projected health needs in a pandemic situation and the current capacity of health care and medical countermeasure systems. Existing pandemic ethics discussions have advocated to engage the public in scarcity dilemmas and attend the local contexts and cultural perspectives that shape responses to a global health threat. This public engagement study thus considers the role of community and culture in the ethical apportionment of scarce health resources, specifically ventilators, during an influenza pandemic. It builds upon a previous exploration of the values and preferences of Maryland residents regarding how a finite supply of mechanical ventilators ought to be allocated during a severe global outbreak of influenza. An important finding of this earlier research was that local history and place within the state engendered different ways of thinking about scarcity.ObjectiveGiven the intrastate variation in the themes expressed by Maryland participants, the project team sought to examine interstate differences by implementing the same protocol elsewhere to answer the following questions. Does variation in ethical frames of reference exist within different regions of the United States? What practical implications does evidence of sameness and difference possess for pandemic planners and policymakers at local and national levels?MethodsResearch using the same deliberative democracy process from the Maryland study was conducted in Central Texas in March 2018 among 30 diverse participants, half of whom identified as Hispanic or Latino. Deliberative democracy provides a moderated process through which community members can learn facts about a public policy matter from experts and explore their own and others’ views.ResultsParticipants proposed that by evenly distributing supplies of ventilators and applying clear eligibility criteria consistently, health authorities could enable fair allocation of scarce lifesaving equipment. The strong identification, attachment, and obligation of persons toward their nuclear and extended families emerged as a distinctive regional and ethnic core value that has practical implications for the substance, administration, and communication of allocation frameworks.ConclusionsMaryland and Central Texas residents expressed a common, overriding concern about the fairness of allocation decisions. Central Texas deliberants, however, more readily expounded upon family as a central consideration. In Central Texas, family is a principal, culturally inflected lens through which life and death matters are often viewed. Conveners of other pandemic-related public engagement exercises in the United States have advocated the benefits of transparency and inclusivity in developing an ethical allocation framework; this study demonstrates cultural competence as a further advantage.
Анализ деятельности по управлению градостроительным процессом в Москве нач. XVIII - конца XX века
Authors: Kuznetsov Sergey 
Published: March 2020

Градостроительный процесс во всём мире, в том числе и в России, носит стадиальный характер, который означает, что этапы активного развития чередуются с фазами замедле­ния. Историков архитектуры всегда интересовали факторы, влиявшие на смену этапов, и вопросы периодизации градо­строительства. Одним из важнейших факторов, влиявших на стадиальность градостроительного развития, является организация системы управления градостроительным про­цессом. Особенно ярко это проявилось в Москве вследствие её уникального положения в иерархии российских городов, особой исторической важности для императоров и по­литических лидеров государства, изменениям столичного административного статуса, а также вызовов, связанных с антропогенными и природными катаклизмами.
История создания и развития структур и механизмов управления градостроительством Москвы началась около трёхсот лет назад, и сама по себе является ценным элементом градостроительной культуры. В статье предпринята попытка с позиции ретроспективного анализа выявить этапы эволюции, их закономерности и различия, разобраться в механизмах выработки решений и взаимодействия субъектов системы управления градостроительным процессом в Москве на про­тяжении длительного исторического периода: с момента переноса столицы в Санкт-Петербург в 1713-1714 годад до возвращения ей столичного статуса в 1918-ом и затем - до превращения в столицу СССР, а затем -Российской Федерации (1991). Это историческое знание полезно как для понимания градостроительного процесса Москвы, так и для создания эффективной модели управления градостроительным раз­витием в будущем.
The Effects of Client Status and the Auditor's Presentation of Multiple Estimation Alternatives on Client Financial Reporting Aggressiveness
Authors: Aghazadeh Sanaz , Collins Andrew M. , Stefaniak Chad M. 
Published: March 2020

ABSTRACT
Accounting estimates are highly subjective and multiple estimation alternatives often exist for a single account. When addressing audit-related adjustments with clients, auditors must decide whether to discuss all possible estimation alternatives or approach the client with only a single, auditor-preferred estimation alternative. In an experiment with experienced CFOs and controllers, we find clients with relatively higher status (operationalized as those with a CPA license) take more aggressive financial reporting positions when the auditor approaches the client with multiple adjustment options based on various estimation alternatives. Our study provides the first evidence that client status is a significant factor in auditor-client negotiations. We also demonstrate how auditors' approach to client negotiations involving multiple allowable estimation alternatives can influence audit quality.
Use of Antihyperglycemic Medications in U.S. Adults: An Analysis of the National Health and Nutrition Examination Survey
Authors: Le Phuc , Chaitoff Alexander , Misra-Hebert Anita D. , Ye Wen , Herman William H. , Rothberg Michael B. 
Published: March 2020

OBJECTIVE
1) To examine trends in the use of diabetes medications and 2) to determine whether physicians individualize diabetes treatment as recommended by the American Diabetes Association (ADA).

RESEARCH DESIGN AND METHODS
We conducted a retrospective, cross-sectional analysis of 2003–2016 National Health and Nutrition Examination Survey (NHANES) data. We included people ≥18 years who had ever been told they had diabetes, had an HbA1c &gt;6.4%, or had a fasting plasma glucose &gt;125 mg/dL. Pregnant women and patients aged &lt;20 years receiving only insulin were excluded. We assessed trends in use of ADA’s seven preferred classes from 2003–2004 to 2015–2016. We also examined use by hypoglycemia risk (sulfonylureas, insulin, and meglitinides), weight effect (sulfonylureas, thiazolidinediones [TZDs], insulin, and meglitinides), cardiovascular benefit (canagliflozin, empagliflozin, and liraglutide), and cost (brand-name medications and insulin analogs).

RESULTS
The final sample included 6,323 patients. The proportion taking any medication increased from 58% in 2003–2004 to 67% in 2015–2016 (P &lt; 0.001). Use of metformin and insulin analogs increased, while use of sulfonylureas, TZDs, and human insulin decreased. Following the 2012 ADA recommendation, the choice of drug did not vary significantly by older age, weight, or presence of cardiovascular disease. Patients with low HbA1c, or HbA1c &lt;6%, and age ≥65 years were less likely to receive hypoglycemia-inducing medications, while older patients with comorbidities were more likely. Insurance, but not income, was associated with the use of higher-cost medications.

CONCLUSIONS
Following ADA recommendations, the use of metformin increased, but physicians generally did not individualize treatment according to patients’ characteristics. Substantial opportunities exist to improve pharmacologic management of diabetes.
Prognostic Significance of Long-term HbA1c Variability for All-Cause Mortality in the ACCORD Trial
Authors: Sheng Chang-Sheng , Tian Jingyan , Miao Ya , Cheng Yi , Yang Yulin , Reaven Peter D. , Bloomgarden Zachary T. , Ning Guang 
Published: March 2020

OBJECTIVE
The association between high glycemic variability and all-cause mortality has been widely investigated in epidemiological studies but rarely validated in glucose-lowering clinical trials. We aimed to identify the prognostic significance of visit-to-visit HbA1c variability in treated patients in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial population.

RESEARCH DESIGN AND METHODS
We studied the risk of all-cause mortality in relation to long-term visit-to-visit HbA1c variability, expressed as coefficient of variation (CV), variability independent of the mean (VIM), and average real variability (ARV), from the 8th month to the transition from intensive to standard glycemic therapy. Multivariable Cox proportional hazards models were used to estimate adjusted hazard ratio (HR) and 95% CI.

RESULTS
Compared with the standard therapy group (n = 4,728), the intensive therapy group (n = 4,755) had significantly lower mean HbA1c (6.6% [49 mmol/mol] vs. 7.7% [61 mmol/mol], P &lt; 0.0001) and lower CV, VIM, and ARV (P &lt; 0.0001). In multivariate adjusted analysis, all three HbA1c variability indices were significantly associated with total mortality in all patients as well as in the standard- and intensive-therapy groups analyzed separately. The hazard ratios for a 1-SD increase in HbA1c variability indices for all-cause mortality were 1.19 and 1.23 in intensive and standard therapy, respectively. Cross-tabulation analysis showed the third tertile of HbA1c mean and VIM had significantly higher all-cause mortality (HR 2.05; 95% CI 1.17–3.61; P &lt; 0.01) only in the intensive-therapy group.

CONCLUSIONS
Long-term visit-to-visit HbA1c variability was a strong predictor of all-cause mortality. HbA1c VIM combined with HbA1c mean conferred an increased risk for all-cause mortality in the intensive-therapy group.
PEMANFAATAN LINGKUNGAN LAHAN BASAH PADA PEMBELAJARAN ASAM BASA MENGGUNAKAN PENDEKATAN CTL TERHADAP KETERAMPILAN BERPIKIR KRITIS
Authors: Yunita Amalia 
Published: March 2020

Ketersediaan lingkungan lahan basah dalam pembelajaran larutan asam basa dapat digunakan sebagai sumber belajar yang dapat digunakan siswa sebaik mungkin untuk meningkatkan keterampilan berpikir kritis. Penelitian ini bertujuan untuk menentukan efektivitas pendekatan CTL yang memanfaatkan lingkungan lahan basah sebagai sumber belajar untuk keterampilan berpikir kritis bagi siswa di sekolah menengah atas pada bab larutan asam-basa. Penelitian ini menggunakan eksperimen semu dengan 2 kelas yaitu kelas kontrol dan kelas eksperimen di SMA Negeri 7 Banjarmasin. Teknik pengambilan sampel yang digunakan adalah cluster random sampling. Variabel bebas adalah pendekatan pembelajaran, sedangkan variabel terikat adalah keterampilan berpikir kritis. Analisis teknik data menggunakan statistik deskriptif dan inferensial. Hasil penelitian menunjukkan bahwa terdapat perbedaan keterampilan berpikir kritis pada kelas eksperimen dan kontrol dengan harga thitung> ttabel yaitu 2,716> 1,996. Perbedaan ini disebabkan oleh kontribusi dari pendekatan CTL seperti konstruktivisme, penyelidikan, pertanyaan, pemodelan, komunitas pembelajaran, dan refleksi yang didukung oleh penggunaan sumber belajar dari lingkungan lahan basah selama proses pembelajaran.Keywords: larutan asam basa, keterampilan berpikir kritis, Pengajaran dan Pembelajaran Kontekstual (CTL), lingkungan lahan basah
Morphology Character and Andrographolide Quantifications on Sambiloto ( Andrographis paniculata (Burm.F.) Nees) Karakter Morfologi dan Kuantifikasi Andrografolid Pada Sambiloto ( Andrographis paniculata (Burm.F.) Nees )
Authors: Prihatini Retno , Syarif Auzar , Bakhtiar Amri 
Published: March 2020

ABSTRACTThe Morphology character and andrographolide quantification on Sambiloto (A. Paniculata) that growth in Sawah Dangka Jorong Gaduik, Tilatang Kamang, Agam (S 00o16159.311 E100o23110.311) have been studied. The Morphology character of A. Paniculata on generative fase have been done in the field and Laboratorium of Biology Department, Andalas University. Quantification of andrographolide constituen were analysed by using High Performance Liquid Chromatography (HPLC) in Chemical of Nature Resources Laboratorium, Pharmacy Faculty, Andalas University. The result showed that Morphology character of Sambiloto ( A. Paniculata ) include parameters ie. range of height plant ( 27-45 cm) ; range of nodus numerous ( 10-14 ); range of leaf-7 size (length; width) ( 3.8-4.1 ; 0.8-1.1) cm; range of branch numerous ( 8-10), leaf dry weight rate (2.482 g ), stem dry weight rate ( 5.882 g ), and day old flowering rate ( 110 day ). The Result of quantification secondary metabolite with high economic value, namely andrographolide showed respectively with level 2.208% (vegetative) and 2.780 % (generative). Key Words : Andrographis paniculata, morpology chracter, andrographolide quantification ABSTRAKTelah dilakukan studi tentang Karakter morfologi dan kuantifikasi senyawa andrografolide pada tanaman Sambiloto (A. Paniculata) yang hidup di Sawah Dangka Jorong Gaduik, Tilatang Kamang, Agam (S 00o16159.311 E100o23110.311). Karakter morfologi A. Paniculata pada fase generative telah dilakukan di lapangan dan di Laboratorium di Jurusan Biologi Universitas Andalas. Kuantifikasi senyawa andrografolid dianalisa dengan menggunakan High Performance Liquid Chromatography (HPLC) di Laboratorium Kimia Bahan Alam, Fakultas Farmasi Universitas Andalas. Hasil menunjukkan bahwa karakter morfologi Sambiloto ( A. Paniculata ) meliputi parameter yaitu kisaran tinggi tanaman ( 27-45 cm) ; kisaran jumlah nodus ( 10-14 ); kisaran ukuran daunke-7 (panjang; lebar) ( 3,8-4,1 ; 0,8-1,1) cm; kisaran jumlah cabang ( 8-10), rata-rata berat kering daun (2,482 g ), rata-rata berat kering batang ( 5,882 g ), and rata-rata umur berbunga ( 110 day ). Hasil kuantifikasi metabolit sekunder dengan nilai ekonomi tinggi, yang dikenal sebagai senyawa andrografolid menunjukkan level 2,208% (vegetatif) dan 2,780 % (generatif). Kata kunci: Andrographis paniculata, karakter morfologi, kuantifikasi andrografolid.