bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Tablet App for Handwriting Skill Screening at the Preliteracy Stage: Instrument Validation Study
Authors: Dui Linda Greta , Lunardini Francesca , Termine Cristiano , Matteucci Matteo , Stucchi Natale Adolfo , Borghese Nunzio Alberto , Ferrante Simona 
Published: October 2020

BackgroundDifficulties in handwriting, such as dysgraphia, impact several aspects of a child’s everyday life. Current methodologies for the detection of such difficulties in children have the following three main weaknesses: (1) they are prone to subjective evaluation; (2) they can be administered only when handwriting is mastered, thus delaying the diagnosis and the possible adoption of countermeasures; and (3) they are not always easily accessible to the entire community.ObjectiveThis work aims at developing a solution able to: (1) quantitatively measure handwriting features whose alteration is typically seen in children with dysgraphia; (2) enable their study in a preliteracy population; and (3) leverage a standard consumer technology to increase the accessibility of both early screening and longitudinal monitoring of handwriting difficulties.MethodsWe designed and developed a novel tablet-based app Play Draw Write to assess potential markers of dysgraphia through the quantification of the following three key handwriting laws: isochrony, homothety, and speed-accuracy tradeoff. To extend such an approach to a preliteracy age, the app includes the study of the laws in terms of both word writing and symbol drawing. The app was tested among healthy children with mastered handwriting (third graders) and those at a preliterate age (kindergartners).ResultsApp testing in 15 primary school children confirmed that the three laws hold on the tablet surface when both writing words and drawing symbols. We found significant speed modulation according to size (P<.001), no relevant changes to fraction time for 67 out of 70 comparisons, and significant regression between movement time and index of difficulty for 44 out of 45 comparisons (P<.05, R2>0.28, 12 degrees of freedom). Importantly, the three laws were verified on symbols among 19 kindergartners. Results from the speed-accuracy exercise showed a significant evolution with age of the global movement time (circle: P=.003, square: P<.001, word: P=.001), the goodness of fit of the regression between movement time and accuracy constraints (square: P<.001, circle: P=.02), and the index of performance (square: P<.001). Our findings show that homothety, isochrony, and speed-accuracy tradeoff principles are present in children even before handwriting acquisition; however, some handwriting-related skills are partially refined with age.ConclusionsThe designed app represents a promising solution for the screening of handwriting difficulties, since it allows (1) anticipation of the detection of alteration of handwriting principles at a preliteracy age and (2) provision of broader access to the monitoring of handwriting principles. Such a solution potentially enables the selective strengthening of lacking abilities before they exacerbate and affect the child’s whole life.
A COMUNIDADE ARTESÃ DO ALTO DO MOURA NO SÉCULO 21
Authors: Sá Marcio , Souza Denise Clementino de , Sousa Jessica Rani Ferreira de , Leal Bárbara Tayná 
Published: October 2020

Este trabalho teve como objetivo caracterizar as tensões disposicionais emergentes entre membros-proprietários(as) de negócios na comunidade artesã do Alto do Moura, Pernambuco, neste século 21. Nesse sentido, são recuperadas discussões acerca dos conceitos de território, urbanização e espaço social na literatura nacional e internacional, que permitiram situar as tensões emergentes na comunidade enquanto um espaço social local em transformação. Apoiando-se na noção de tensão disposicional (Bourdieu) como instrumento teórico e metodológico, a pesquisa foi norteada por uma abordagem epistêmica construtivista e utilizou como intrumentos para o trabalho de campo entrevistas semiestruturadas, notas de campo e grupos focais. As principais tensões disposicionais analisadas foram referentes às novas paisagens, vizinhanças e à insegurança comunitária, associadas aos conjuntos habitacionais mais recentes e a seus novos moradores, e à concorrência exacerbada e ao fator classe na aceitação social, relativos às mudanças no padrão de relacionamento comunitário.
Palavras-chave: Comunidade artesã. Alto do Moura. Espaço social local. Tensões disposicionais emergentes.
CATADORAS DE MATERIAIS RECICLÁVEIS E O CUIDADO EM SAÚDE
Authors: Vasconcelos Joaquim Pedro Ribeiro , Bruna Carvalho Barros Rosa Nobre  , Izabel Cristina Bruno Bacellar Zaneti  , Sílvia Maria Ferreira Guimarães  
Published: October 2020

As trabalhadoras catadoras de materiais recicláveis são fundamentais na promoção de ações sustentáveis para a proteção do meio ambiente, apesar de viverem num cenário de precarização da vida. Diante disso, este artigo tem como objetivo compreender o contexto de vida e o cuidado em saúde dessas mulheres na lida cotidiana. Este estudo revela o universo dessas trabalhadoras informais organizadas em uma associação com sede em Ceilândia (DF). Foram realizadas entrevistas semiestruturadas com as catadoras, sendo complementada pela observação de suas atividades cotidianas no galpão de triagem de materiais recicláveis. Os achados apontam para questões marcantes relativas a: precariedade do trabalho na lógica da reestruturação produtiva do capital; opressões das mulheres na perspectiva interseccional de raça, gênero e classe; as dificuldades do acesso aos serviços oficiais de saúde. Especialmente, é discutido também as experiências relacionadas à assistência à saúde e à rede popular de compartilhamento do cuidado como forma de resistência.
Palavras-chave: Trabalho. Catadoras de materiais recicláveis. Sociabilidades. Saúde.
INVISIBILIDADES, INSURGÊNCIAS E EMERGÊNCIAS
Authors: Recoaro Deise , De Menezes Marilda Aparecida , Jard da Silva Sidney , Santos Júnior Jaime 
Published: October 2020

Neste artigo, apresentamos os resultados parciais de uma pesquisa sobre as trajetórias de vida de mulheres que participaram do ciclo de greves históricas do ABC Paulista. Desse recorte mais amplo, fizemos uma incisão neste texto para trazer, na composição dos casos, as memórias de mulheres que assumiram cargos na estrutura sindical. Na hipótese de que os efeitos das formas de opressão que marcavam as trajetórias ocupacionais das mulheres na indústria metal-mecânica e nas montadoras do parque automotivo dessa região ecoavam nas estruturas sindicais, reproduzindo clivagens de gênero, importa-nos compreender as estratégias de resistência, as formas de engajamento na militância e os efeitos na ação sindical. As memórias deixam entrever o lento processo de reconhecimento das demandas de gênero, a perenidade das tensões relativas a essa clivagem nas estratégias de luta e as disputas discursivas por legitimidade das histórias das mulheres na narrativa sobre as greves do ABC Paulista.
Palavras-chave: Sindicalismo. Greves. Gênero. ABC Paulista.
SINDICALISMO, AUTORITARISMO E REPRESSÃO ENTRE DOIS POLOS
Authors: Marinho Maria Gabriela Silva Martins da Cunha , Meza Eliane Cristina de Carvalho Mendoza , Fonseca Karen Christina Dias da 
Published: October 2020

O artigo analisa, em perspectiva histórica, aspectos da repressão desencadeada pelo acirramento político de 1968, com ênfase nas greves de Osasco e reverberações no ciclo posterior do ABC paulista no final da década de 1970. Constrói a análise a partir da produção memorialística de personagens do período a partir de um ângulo menos frequente, no caso, a perspectiva dos agentes do status quo e da repressão política. Nesse sentido, localiza a participação do Exército e de empresários que se destacaram, sobretudo, na conjuntura de 1968, um dos momentos mais agudos do fechamento político durante o regime militar. O argumento desenvolvido pressupõe a mudança de escala e natureza da repressão e seu deslocamento de forças marcadamente policiais para a vinculação ao escopo das “atribuições” das Forças Armadas, em particular do Exército. Desse modo, sindicatos e sindicalistas passaram a compor o espectro do “inimigo interno” definido na Doutrina de Segurança Nacional. Um dos aspectos destacados é o caráter estratégico do setor metalúrgico sobre o qual a repressão incidiu pesadamente, segmento no qual muitas empresas estiveram associadas ao capital internacional. Por outro lado, além de assinalar a especificidade da atuação militar na repressão sindical, o artigo procura agregar como elemento de análise a presença do empresariado na escalada repressiva.

Palavras-Chave: Autoritarismo e repressão. Ditadura Civil-Militar e sindicalismo. Memória de greves e acirramento político. São Paulo e o estado de exceção.
Association of Maternal Prepregnancy Diabetes and Gestational Diabetes Mellitus With Congenital Anomalies of the Newborn
Authors: Wu Yuxiao , Liu Buyun , Sun Yangbo , Du Yang , Santillan Mark K. , Santillan Donna A. , Snetselaar Linda G. , Bao Wei 
Published: October 2020

OBJECTIVE
To examine the association of maternal prepregnancy diabetes, gestational diabetes mellitus (GDM), and 12 subtypes of congenital anomalies of the newborn.

RESEARCH DESIGN AND METHODS
We included 29,211,974 live births with maternal age ranging from 18 to 49 years old documented in the National Vital Statistics System in the U.S. from 2011 to 2018. Information on prepregnancy diabetes, GDM, and congenital anomalies was retrieved from birth certificates. Log-binomial regression was used to estimate risk ratios (RRs) and 95% CIs for congenital anomalies overall and by subtypes.

RESULTS
Of the 29,211,974 live births, there were 90,061 infants who had congenital anomalies identified at birth. The adjusted RRs of congenital anomalies at birth were 2.44 (95% CI 2.33–2.55) for prepregnancy diabetes and 1.28 (95% CI 1.24–1.31) for GDM. The associations were generally consistent across subgroups by maternal age, race/ethnicity, prepregnancy obesity status, and infant sex. For specific subtypes of congenital anomalies, maternal prepregnancy diabetes or GDM was associated with an increased risk of most subtypes. For example, the adjusted RRs of cyanotic congenital heart disease were 4.61 (95% CI 4.28–4.96) for prepregnancy diabetes and 1.50 (95% CI 1.43–1.58) for GDM; the adjusted RRs of hypospadias were 1.88 (95% CI 1.67–2.12) for prepregnancy diabetes and 1.29 (95% CI 1.21–1.36) for GDM.

CONCLUSIONS
Prepregnancy diabetes and, to a lesser extent, GDM were associated with several subtypes of congenital anomalies of the newborn. These findings suggest potential benefits of preconception counseling in women with preexisting diabetes or at risk for GDM for the prevention of congenital anomalies.
El perfil del docente de física como factor en el desarrollo de las competencias del estudiante en el bachillerato
Authors: Gómez Jiménez Irene , Ramírez Díaz Mario Humberto , Arriaga Santos Carlos Adrián 
Published: October 2020

La Escuela Preparatoria No. 7 del Sistema de Educación Media Superior (SEMS), perteneciente a la Universidad de Guadalajara (UdeG), cuenta con el modelo educativo Bachillerato General por Competencias, el cual plantea un proceso de enseñanza-aprendizaje con una orientación constructivista, que busca que el estudiante desarrolle competencias mediante la aplicación del conocimiento tomando en cuenta el contexto y la realidad social. Dentro del perfil académico del docente que imparte la unidad de aprendizaje de Física II, se menciona la necesidad de relacionar las competencias técnico-pedagógicas y la experiencia en un campo disciplinar análogo, con el propósito de realizar planeaciones didácticas, diseño, evaluación de estrategias y actividades de aprendizaje orientadas al desarrollo de competencias. Sin embargo, al terminar el bachillerato e ingresar al nivel superior, los estudiantes no obtienen notas favorables. El presente trabajo busca determinar las competencias, habilidades y conocimientos que deberá poseer un docente que enseña física para lograr que el estudiante desarrolle las competencias necesarias según el perfil de egreso en la educación media superior. Para ello, se presenta un análisis histórico de los resultados de la evaluación por competencias mediante los exámenes transversales, el perfil de los docentes (disciplinar y pedagógico), así como una evaluación docente realizada por los alumnos, una entrevista al director del plantel, a los docentes y a los estudiantes. Con ello se identifican las estrategias de actualización y capacitación para los docentes que imparten clases en la unidad de aprendizaje de Física II en la Escuela Preparatoria No. 7.
Chemical and Toxicological Diagnosis of Acute Poisoning with Clozapine, Olanzapine, Quetiapine and Risperidone
Authors: Belova M. V. , Klyuyev E. A. , Melnikov E. S. , Poryadina M. N. 
Published: October 2020

Relevance The large number of atypical antipsychotic drugs on the market , the breadth of their medical and non-medical use, and their relative affordability make atypical antipsychotics common causes of overdose, suicidal actions or non-medical use of drugs. At the same time, they remain insufficiently studied from the chemical and toxicological point of veiw.Aim od study: creation of available express method of detection of clozapine, olanzapine, quetiapine and risperidone in the urine of patients with acute poisoning.Material and methods Thin layer chromatography (TLC), gas chromatography with mass selective detection (GC-MS), and high performance liquid chromatography with mass selective detection (HPLC-MS/MS) were used. The preparation of intact urine samples with addition of standard solutions of clozapine, olanzapine, quetiapine, risperidone and urine samples of patients with symptoms of acute poisoning with given drugs was carried out by methods of liquid-liquid extraction at alkaline pH values for TLC chloroform, a mixture of ethyl acetate-diethyl ether (1:1) for GC-MS and acetonitrile for HPLC-MS/MS.Results A TLC method has been developed to detect clozapine, olanzapine, quetiapine and risperidone, which allows its the presence to be quickly revealed in the patient’s urine at the preliminary examination stage and also distinguish them from each other in case of the same type of symptoms of poisoning. For confirmatory analysis, it is advisable to use the methods of HPLC-MS/MS and GC-MS. Compared to confirmatory methods, the developed TLC-screening technique is expressive, does not require the use of expensive high-tech equipment and allows clozapine, olanzapine, quetiapine and risperidone to be differentiated from other toxicologically significant psychoactive substances found in general screening.
The Choice of Vascular Implants in Accordance with Age-Related Vessel Changes
Authors: Lipatov V. A. , Grigoryev N. N. , Severinov D. A. , Sahakyan A. R. 
Published: October 2020

Background Today, one of the problems of modern society in the health are the high rates of mortality from cardiovascular disease.Aim of study Study of physico-mechanical properties of the vascular implants and aortic wall to support an adequate choice of the plastic material when performing reconstructive surgeries in patients of various age groups.Material and methods As an object of study, sections of the anterior wall of the thoracic and abdominal aorta were taken from 30 corpses. Study groups: Group 1 - from 33 to 60 years, Group 2 - from 60 to 92 years. We also evaluated the physical and mechanical properties (finite length, plastic strain ratio, tensileuniaxial load (longitudinal)) of the three vascular implants made of polyethylene terephthalate and polytetrafluoroethylene. Kruskal–Wallis H test was used to determine the significance of differences.Results The finite length of the aortic wall varies slightly in the study groups, while plastic strain rate of the abdominal aorta in Group 1 was 1.3 times higher than that in the chest. When assessing physical and mechanical properties of thoracic and abdominal aorta, values of “finite length” (1.4 times) and “plastic strain ratio” (1.5 times) were higher in Group 1, and the value of the tensile load indicator is higher in Group 2 compared to Group 1 (1.47 times). The tensile load of the thoracic aorta in Group 1 is 14 H and 27 H lower than the samples of Groups 1 and 3, respectively, but 1.6 times higher than the sample of Group 2. The tensile load of the abdominal aorta of Group 1 is 13 H higher compared to the sample of Group 1 and twice higher compared to the sample of Group 2. The study Group 2 values of tensile load for thoracic aorta are 1.3 times, 2.4 times and 1.16 times higher than respective implant values (sample 1, 2 and 3, respectively).Conclusion We used samples of Group 3 vascular implants for replacement of abdominal aorta and Group 1 implants for thoracic aorta. In study Group 2 vascular implants of Group 3 may be used for abdominal and thoracic aorta replacement due to the proximity of the values of the evaluated characteristics.
Organization of First Aid in the Arkhangelsk Region
Authors: Baranov A. V. 
Published: October 2020

Background The development and implementation of widespread training for rules, techniques and methods of providing first aid to the widest possible range of people will significantly reduce the level of disability and mortality among victims of road traffic accidents (RTAs).Aim of study To study the organization of first aid for the victims in the Arkhangelsk region.Material and methods Part 1. The journals of registration of attendance at classes with a trained contingent in the educational-methodical department of the School of Disaster Medicine of the Territorial Center for Disaster Medicine of the Arkhangelsk Region for the period from 01.01.2012 to 12.31.2018 are analyzed. Part 2. We selected 906 medical records of patients (003/u) affected by an accident on the federal highway M-8 “Kholmogory” and treated in hospitals of Arkhangelsk region, admitted acutely in period from 01.01.2012 till 31.12.2018. The study was conducted according to the criteria of retrospective continuous documentary observation. As a criterion of statistical significance, the probability of a random error of less than 5% (p<0.05) was applied using the correction for multiple comparisons (Bonferroni correction).Conclusion 1. The educational activities of the TCDH of the Arkhangelsk Region over a seven-year period are characterized by a significant increase in the total number of trained cadets (p<0.001); 2-fold increase in the number of trained motor vehicle drivers (p<0.001) and employees of Ministry of Emergency Situations and Russian Interior Ministry (p<0.001). 2. The first aid to injured in an accident on the federal highway M-8 Kholmogory in the Arkhangelsk Region was provided in 65 cases (7.2%); in almost 90% of cases, first aid was recorded in the Arkhangelsk and Severodvinsk medical districts of the Arkhangelsk region (p<0.001).
Peritoneal Laser Doppler Flowmetry in Predicting and Diagnosing Tertiary Peritonitis
Authors: Parshin D. S. , Topchiyev M. A. 
Published: October 2020

Relevance. The article is devoted to one of the most difficult and controversial problems in the treatment of intra-abdominal infection, the prediction and diagnosis of tertiary peritonitis. The technique of peritoneal laser Doppler flowmetry (PLDF) makes it possible to assess the degree of visceral microcirculation disorders in various diseases of the abdominal organs.Aim of study. To identify early, trigger indicators of peritoneal microcirculation in tertiary peritonitis, obtained by the PLDF method.Material and methods. A retrospective analysis of the results of treatment of 48 patients operated on for secondary diffuse purulent peritonitis in the clinic of general surgery of the Astrakhan State Medical University in the period from 2015 to 2019 was carried out. All patients were divided into two equal groups: the main group with subsequently developed tertiary peritonitis, and the comparison group with arrested peritonitis. The study of peritoneal microcirculation was performed at the time of laparotomy, after debridement, 24 and 48 hours later. A total of 768 scans were performed. Evaluation was carried out using the APACHE II scales , abdominal index and SOFA scale. Spearman’s rank correlation test was one of the main statistical methods.Results. Twenty-four hours after the primary operation, the values of the percentage of microcirculation, standard deviation and coefficient of variation showed a direct correlation with the development of tertiary peritonitis. According to Spearman’s criterion, the closeness of the relationship according to these indicators was: r=0.71, r=0.55, r=0.63, respectively, at p≤0.05. After 48 hours, all the studied values of microcirculation made it possible to diagnose tertiary peritonitis. The data obtained correlated with the data obtained by the systems for assessing the severity of the patient’s condition.Conclusion. 1. The generally accepted scales for assessing the severity of patients’ condition (APACHE II, abdominal index and SOFA) used in patients with diffuse purulent peritonitis do not allow predicting the risk of tertiary peritonitis 24 hours after surgery. The data obtained as a result of the scoring on the above scales becomes representative 48 hours after the initial intervention. 2. The percentage of microcirculation, standard deviation and coefficient of variation can be used as early screening indicators of peritonetal laser Doppler flowmetry to predict tertiary peritonitis 24 hours after primary surgery. 3. The whole range of indicators of peritoneal laser Doppler flowmetry allows the degree of impairment of the tissue microcirculation in patients with peritonitis to be objectively assessed even 48 hours after the initial operation and to be diagnostic criteria of tertiary peritonitis.