bluuebunny/crossref_metadata_2025_split huggingface dataset:
Behavioural risk factors for non-communicable diseases amongst adults aged 18 years and above in Collins Chabane Municipality of Vhembe District in Limpopo Province, South Africa
Authors: motadi selekane , Sambo Charmaine , Nesengani Nthovhedzeni , Ndalani Thembuluwo , Mutakuseni Rilwele 
Published: March 2020

Abstract
Background: Tobacco use, alcohol consumption, physical inactivity, unhealthy diet and obesity are the behavioural risk factors for non-communicable diseases. To determine behavioural risk factors for non-communicable diseases amongst adults aged 18 years and above in Collins Chabane municipality of Limpopo province, South Africa. Methods: This study included 365 participants recruited from Collins Chabane municipality of Vhembe district, Limpopo province, South Africa. Municipality was selected using simple random sampling and convenience sampling was used to choose participants. Anthropometric measurements were measured following standard techniques. Data on dietary intake was collected using Food Frequency Questionnaire. Permission and clearance were obtained and participant’s rights were respected. Results: About (24.4%) of participants consumed alcohol in the current study. Males were more likely to consume alcohol as compared to female counterpart (54.6% vs. 3.3 %) Gender has a large effect on alcohol consumption. Cramer’s V = 0.58. The prevalence of alcohol consumption was higher in male (22.8%) as compared to (1.6%) female counterparts. The prevalence of underweight, overweight and obesity was 7.7%, 29.8%, and 11.3%, respectively. Majority 61.1% of the participants had sedentary lifestyle in the current study. About 13.9% of the participants smoked cigarette in the current study. Of all participants who smoked cigarette 10.1% initiated smoking at the age of less than 19 years Conclusion: Behavioural risk factors such as smoking, alcohol consumption, consumption of over required amount of sugar, sodium, protein, energy, carbohydrates, excessive fats intake, physical inactivity, overweight, obesity exist among people in Collins Chabane municipality.
Understanding the Barriers to Nurses Error Reporting and Disclosure: A Mixed Methods Study
Authors: Najafpour Zhila , Arab Mohammad , biparva somayeh , Yaseri Mehdi , Hatamizadeh Maryam , Goudarzi Zahra , Bahramnezhad Fatemeh , Shayanfard Kamran 
Published: March 2020

Abstract
Background: Ensuring that nurses report errors and disclose related outcomes to patients is a movement toward creating a culture of transparency. Different factors might contribute to the tendency to under-report or to disclose. This study aim to investigate the barriers of the reporting and disclosing of medical errors via nurses’ perceptions.Methods: A mixed methods study were used to identify barriers of error reporting and disclosing. For the aim of this study, a total of 491 nurses participated in the quantitative phase and 22 nurses in the qualitative phase, Iran, 2018. The data for the quantitative phase was collected based on a questionnaire and were next analyzed by descriptive and analytical statistics. Through a scenario-based method, the qualitative data were gathered and analyzed based on content analysis approach.Results: The results showed that the most important perceived barriers with the highest impacts coincided with educational(64%), motivational(64%), and managerial factors (62%) and the univariate analysis showed a significant correlation between error-reporting mechanisms, education, and consequences of reporting errors domains and independent variables(p < 0.05). Based on SEM analysis, the most important perceived barriers were educational and motivational domains (ES:1.33, SE:0.16). Interview results were classified into three categories: error perception, error reporting, and error disclosure. In fact, 55% of the interviewed nurses identified the existence of at least one error in scenarios and 66% of participants stated that they had reported errors. Overall 83% of the participants recruited had negative attitude toward full disclosing the errors to patients.Conclusions: Our results highlight the multifactorial aspects in error reporting and disclosing. Lack of knowledge about error and its reporting, inappropriate feedback and weakness in supportive actions represent the inhibitors of reporting and disclosing errors. Actually, a guideline should be formulated on error disclosure to increase transparency and improve communication with patients.
Research on Space-time Blocking Matrix Algorithm Based on Frequency Diverse Array
Authors: Liao Yanping , Wu Zenan 
Published: March 2020

Abstract
Because the beam pattern of the conventional phased array or MIMO radar is only related to the angle dimension, it is difficult to suppress the incident interference when it is in the mainlobe or at the same angle of the desired signal. According to the development demand of mainlobe anti-interference technology. In this paper, a space - time blocking matrix processing algorithm based on FDA is proposed. The algorithm gives the specific structure of the blocking matrix, which can not only avoid the interference of the same angle and different distances, but also eliminate the interference signal in the direction of the mainlobe without affecting the energy of other incident signals, so as to ensure the good shape of the beam pattern. The simulation results show that the algorithm can successfully suppress the mainlobe interference and has good beam-conformal.
The effects of synbiotic supplementation on metabolic factors and systemic inflammation in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled study
Authors: Velayati Aynaz , Kareem Iman , Sedaghat Meghdad , Sohrab Golbon , Nikpayam Omid , Hedayati Mehdi , Abhari Khadijeh , Hejazi Ehsan 
Published: March 2020

Abstract
Background: Type 2 diabetes is a common metabolic disorder in the world, and it has become a challenge for the health system. Some studies have indicated the desirable effects of synbiotics on metabolic factors in patients with diabetes. Aim: This study aimed to determine the effect of synbiotic supplementation on metabolic factors and systemic inflammation in patients with type 2 diabetes mellitus. Methods: In this randomized, double-blind controlled trial, 50 patients with type 2 diabetes randomly allocated to the synbiotic (containing Bacillus coagulans + Lactobacillus rhamnosus + Lactobacillus acidophilus and fructooligosaccharide) or placebo groups to received one sachet daily for 12 weeks. Glycemic index, Lipid profile, and hs-CRP measured at the beginning of the study and the end of the 12th week. Results: After 12 weeks, supplementation means a change of Hip circumference (HC) significantly decreased in the synbiotic group compared to the placebo group (-0.85±1.89 vs. 1.23±3.98). Although systolic blood pressure (SBP) and diastolic blood pressure (DBP) at the end of trial declined in the synbiotic group compared to baseline, respectively p=0.03, p=0.01. Analysis of covariance demonstrated that synbiotic supplementation during 12 weeks significantly reduced glycemic factors including fasting blood glucose (FBG), insulin, homeostatic Model Assessment for Insulin Resistance (HOMA-IR), β-cell function (HOMA-β) (p<0.05) and inflammatory index, hs-CRP (p<0.05) compared to placebo. Conclusion: The current study indicated Synbiotic supplementation could improve glycemic index, systemic inflammation and blood pressure in patients with type 2 diabetes. So correcting the intestinal microbial flora can be a new therapeutic approach to treating this disease. Trial registration: IRCT, IRCT20100524004010N27. Registered 7 January 2019, https://www.irct.ir/trial/36535
Impact of Cardiovascular Screening Tests in Patients with Type 2 Diabetes Mellitus without Previous Histories of Cardiovascular Disease: 5-year Clinical Outcomes.
Authors: Antoku Yoshibumi , Takemoto Masao , Mito Takahiro , Shiiyama Ryuta , Otsuka-Morisaki Hiroko , Tanaka Atsushi , Maeda Yasutaka , Tsuchihashi Takuya 
Published: March 2020

Abstract
Background We previously reported that, among the asymptomatic patients with type 2 diabetes mellitus (T2DM) without history of cardiovascular disease (CVD), up to 19% of the patients with myocardial ischemia were detected by cardiovascular screening tests (CVSTs). We concluded that the CVSTs in patients with T2DM may be one of the most effective strategies to find CVD in those patients. Thus, the aim of the study was to assess the long-term clinical outcomes of CVSTs in patients with T2DM without previous histories of CVD. Methods Six hundred fifty-seven out-patients with T2DM who received CVSTs at least more than one time or not at all from April in 2014 to March in 2019 were defined as the S group or NS group, respectively. The data in 2104 and 2018 were collected from the medical records, and compared between the S and NS groups. Results This study revealed that, in the out-patients with T2DM in our hospital over those 5 years; 1) the frequency of receiving CVSTs was significantly increasing, 2) in accordance with that increase, the frequency of the internal use for CVD of statins, anti-platelets, and renin-angiotensin system inhibitors, which are well-known as medications for preventing CVD, was significantly increasing, 3) however, there was only a small increase in the internal use of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptors, which are well-known to suppress cardiovascular events in patients with T2DM, 4) LDL-cholesterol and triglycerides significantly improved more in the S group than the NS group, 5) highly sensitive C-protein, which is one of the strongest predictors of CVD, was significantly suppressed by CVSTs, 6) the progression of renal dysfunction was significantly more suppressed in the S group than the NS group, 7) in an inverse proportion to the CVST increase, the frequency of acute coronary syndrome, cerebral infarctions, 4-point major adverse cardiovascular events, and admissions due to heart failure were significantly decreasing, and 8) finally, the frequency of all-cause mortality was significantly suppressed during those 5 years. Conclusions Thus, it may be important to continue CVSTs in out-patients with T2DM without a previous history of CVD for several years.
Assessing the determinant Factors leading to Academic Staffs' level of Satisfaction and Turnover Intention in Universities, In Case of the Amhara Region, Ethiopia.
Authors: Berhie Kidanemariam Alem , Mohammed Kasim , Arega Yibeltal , Melese Dessie , Ibrahim Adem , Hussen Jemila 
Published: March 2020

Abstract
Background: Job satisfaction is the most interesting field for many researchers to study work attitude in workers. Employee job satisfaction is fulfillment, gratification, and enjoyment that comes from work. The main objective of this study is to identify and analyze the determinant factors leading to academic staff’s satisfaction and turnover intention in the Amhara regional state universities.Methods: The study was conducted in seven Amhara regional state government universities. Cross-sectional stratified sampling design was used. The stratum is based on these seven universities in Amhara regional state. In this investigation, ordinal logistic regression model was used.Results: The study covers 620 respondents from September 2016 up to August, 2017. The sample staffs surveyed from UOG, BDU, Wollo, Debre-Birihan, Debre-Markos, Debre-Tabor and Welidiya University were 21.3%, 23.7%, 9.4%, 7.6%, 14.5%, 12.1% and 11.5%, respectively. From these total respondents, 34.4% were satisfied with their job. From the total sample staff surveyed in the study, 26.0% were dissatisfied. 9.2%, 29.8% and 0.6% of the respondents were very dissatisfied, neutral and very satisfied in their jobs, respectively. 38.5% of the respondents were very eager to leave their job areas.Conclusions: The independent variables sex, age, place of birth, employer University, job position, responsibility, advancement, salary, achievement, work condition, work itself and turnover have significant relation with an academic job satisfaction.
Comparative transcriptome analysis identifies jasmonic pathway genes related to anther dehiscence in Solanum melongena L.
Authors: Wang Zhimin , Zhang Shaowei , Yuan Chao , Niu Yi , Tang Qinglin , Wei Dayong , Tian Shibing 
Published: March 2020

Abstract
Background: Anther indehiscence is an important form of functional male sterility that can facilitate the production of hybrid seeds. However, the molecular mechanisms of anther indehiscence-based male sterility in eggplant (Solanum melongena L.) have not been thoroughly explored. Therefore, we performed RNA-seq analysis to investigate the molecular mechanisms of anther dehiscence in eggplant. Results: We used transcriptome sequencing and qRT-PCR assays to compare the anthers of normally developing (F142) and anther indehiscent (S12) eggplant. We identified 2670 differentially expressed genes between lines. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses identified 31 differentially expressed genes related to hormone biosynthesis. We therefore measured the contents of the phytohormones jasmonic acid (JA), IAA, GA3 and ABA in S12 and F142. There were no significant differences in IAA, GA3 or ABA levels between S12 and F142. However, JA levels were significantly lower in S12 than in F142. Five key genes in the JA signaling pathway were differentially expressed in S12 vs. F142. Of these, SmJAZ and SmJAR-like were significantly up-regulated and SmDAD1, SmLOX and SmCOI1 were down-regulated in S12 vs. F142. In DNA-protein interaction studies, SmLOX, SmAOC, SmOPR3, SmCOI1 and SmJAZ1 failed to be enriched on the chromatin of SmDAD1. Protein–protein interaction studies identified a direct interaction between SmDAD1 and SmLOX, but SmDAD1 failed to interact with SmAOC, SmOPR3, SmCOI1 and SmJAZ1. Conclusion: JA is an essential factor affecting anther dehiscence in eggplant. SmDAD1 interacts with SmLOX to alter JA levels, thereby regulating anther dehiscence. Our data represent a valuable resource for further exploring the regulatory mechanisms underlying anther dehiscence in eggplant.
Predictive value of two polymorphisms in ABCB1, rs1045642 and rs1128503, in prognosis following taxane-containing chemotherapy: A meta-analysis
Authors: Chen Quanyao , Lin Wanlong , Yang Jianhui , Lin Min , Lin Xiuxian , Huang Jiangfeng , Weng Yiyin , Guo Jujiang , Chen Yao 
Published: March 2020

Abstract
Background: Although taxane-containing chemotherapy is widely used to treat solid tumors, genetic polymorphisms can influence the chemotherapeutic response. This meta-analysis was conducted to determine the correlation between two polymorphisms in ABCB1 , rs1045642 and rs1128503, and survival of patients administered taxane-containing chemotherapy. Methods: PubMed, Web of Science, Embase, Wanfang database, VIP database, and China National Knowledge Infrastructure database were used to obtain articles published up to August 2019 describing the association between the ABCB1 rs1045642 and rs1128503 polymorphisms and survival. A meta-analysis was conducted using R 3.6.1 software to determine the pooled hazard ratio (HR) and 95% confidence intervals (95% CI). Furthermore, publication bias was assessed, and sensitivity analysis was performed to validate the analysis. Results: Fifteen studies involving 3320 patients were included in the meta-analysis. The summary results showed that the effect of the C1236T polymorphism on progression-free survival remained significant in the heterozygote model (HR 0.81; 95% CI: 0.67–0.98) and homozygote model (HR 0.71; 95% CI: 0.58–0.88). Compared to the C1236 TT phenotype, the CC genotype was associated with a poor overall survival (HR 0.72; 95% CI: 0.53–0.97). Finally, subgroup analysis suggested that different areas, tumor types, and treatment regimens influence patient survival. Conclusions: Patients who are ABCB1 rs1045642 and rs1128503 T gene carriers show a survival benefit with taxane-containing chemotherapy.
Spatial, Temporal, and Spatiotemporal Variation of Malaria Incidence and Risk Factors in West Gojjam Zone From 1 July 2013- 30 June 2018, Northwest Ethiopia, 2019.
Authors: Bayih Eniyew Tegegne , Gelaye Kassahun Alemu , Zeleke Awrajaw Dessie , Damtew Alebachew Shimelash , Asmare Biachew Asmare , Demil Yikeber Argachew , Lamore Yonas Lamore , Temesgen Tegegne Temesgen , Melessie Biruk Demissie 
Published: March 2020

Abstract
Background: Malaria is a life-threatening acute febrile illness which is affecting the lives of millions globally. Its distribution is characterized by spatial, temporal, and spatiotemporal heterogeneity making detection of the space-time distribution and mapping high-risk areas useful to effectively targeting hot spots of malaria for intervention. Methods : Time series cross sectional study was conducted using data obtained from weekly malaria surveillance reports stored in the Amhara Public Health Institute from 1 July 2013-30 June 2018. Climatic variables were obtained from West Amhara Meteorological Agency. All districts were included and geo-coded and the spatial data was created in ArcGIS10.2.2 software. Global and local spatial autocorrelation were used to test the hypothesis and to detect hot spots respectively. The Poisson model was fitted to determine the purely spatial, temporal, and space-time clusters using SaTScan™9.6 software. Spearman correlation, bivariate, and multivariable negative binomial regressions were used to analyze the relation of the climatic factors to count of malaria incidence. Result: The study revealed spatial, temporal, and spatiotemporal heterogeneity of malaria incidence. Jabitenan, Quarit, Sekela, Bure, and Wonberma were high rate spatial cluster of malaria incidence hierarchically. Spatiotemporal clusters were detected. A temporal scan statistic identified one risk period from 1 July 2013 to 30 June 2015. Monthly average temperature was positively but monthly average rainfall and monthly average relative humidity were negatively correlated to count of malaria incidence at all lag-months. The adjusted incidence rate ratio showed that monthly average temperature and monthly average rainfall were independent predictors for malaria incidence at all lag-months. Monthly average relative humidity was significant at 2 months lag. Conclusion: Malaria incidence had shown spatial, temporal, spatiotemporal variability in West Gojjam zone. Mean monthly temperature and rainfall were directly and inversely associated to count of malaria incidence respectively. Considering these space-time variations and risk factors (temperature and rainfall) would be useful for the prevention and control and ultimately achieve elimination. Keywords: Spatiotemporal Variation, Malaria Incidence, Risk Factor, West Gojjam, Ethiopia
The treatment of distal radius fractures accompanying dorsally displaced free fragments beyond the watershed line with turning radius and distal volaris radius system plate fixation via the distal palmar approach
Authors: Jia Zhaofeng , Wang Shijin , Jiang Wei , Li Chuangli , Lin Jiandong , Liu Qisong , Li Guangheng , Hu Xinjia 
Published: March 2020

Abstract
Background: Although distal radius fractures (DRFs) are clinically common, DRFs accompanied by dorsally displaced free fragments beyond the watershed line are much less so. At present, it is very difficult to fix and stabilize the displaced free fragments far away from the watershed line with a plate. Our aim was to investigate the clinical effect of DRFs with distally displaced dorsal free mass treated with distal volaris radius (DVR) combined with turning of the radius via the distal palmar approach. Methods: From 2015 to 2019, 25 patients with distal radius fractures associated with dorsally displaced free fragments beyond the watershed line were selected and treated with distal volaris radius (DVR) combined with turning of the radius via the distal palmar approach. This study involved 14 males and 11 females, with an average age of 34.5 years (ranging from 21 to 50 years). The mean follow-up period was 16.5 months (ranging from 12 to 22 months). The dorsal displacement of the free fragments was analyzed by X-ray and three-dimensional computed tomography, allowing characterization of postoperative recovery effects by radial height, volar tilt and radial inclination. For the follow-up, we evaluated effects of the surgery by analyzing range of motion (ROM); Modified Mayo Wrist Score (MMWS); and Disabilities of Arm, Shoulder and Hand (DASH) score. Postoperative wound recovery and complications were also monitored to evaluate the clinical therapeutic effects of the surgical procedures. Results: X-ray showed that all patients showed reduced fractures, well-healed wounds and recovered function with no obvious complications. Based on the follow-up, patients had a mean radial height of 10.5mm (ranging from 8.1 to 12.6 mm), mean MMWS of 78.8° (ranging from 61 to 90°), mean DASH score of 16.25 (ranging from 11 to 21), mean ROM for volar flexion of 76.5° (ranging from 62 to 81°), mean ROM for dorsiflexion of 77.1° (ranging from 59 to 83) and mean VAS score of 1.4 (ranging from 1 to 3). Conclusion: Treatment of distal radius fractures with accompanying dorsally displaced free fragments beyond the watershed line with turning of the radius and the DVR plate system via the distal palmar approach is effective and has no obvious complications.
Lymphoepithelioma-like hepatic carcinoma: A report of 3 cases and review of the literature
Authors: Zhang Kai , Tao Changcheng , Wu Fan , An Songlin , Rong Weiqi , Wu Jianxiong 
Published: March 2020

Abstract
Background: Lymphoepithelioma-like hepatic carcinoma is a rare distinctive variant of liver cancer with unique epidemiological and pathological characteristics, characterized by dense lymphocyte infiltration. It can be divided into lymphoepithelioma-like hepatocellular carcinoma and lymphoepithelioma-like intrahepatic cholangiocarcinoma. Existing research shows that its prognosis is good. Up to now, only 101 cases have been reported. More rarely, combined lymphoepithelioma-like hepatocellular carcinoma and cholangiocarcinoma has been found. Case presentation: The first patient was a 62 years old Chinese man with hepatitis B virus infection presented with a single lesion in the liver. The patient underwent surgical treatment and was discharged on the 4th day. The patient was diagnosed as combined lymphoepithelioma-like hepatocellular carcinoma and cholangiocarcinoma and has been alive for 15 months. The second patient was a 63 years old Chinese woman with right upper abdominal pain and hepatitis B virus infection. The imaging examination a single lesion in the liver. The patient underwent surgical treatment and was discharged one week later. The patient was diagnosed as lymphoepithelioma-like hepatocellular carcinoma and was considered to be the recurrence of lymph nodes about 2 years after operation. The patient underwent local radiotherapy and has been alive for 60 months. The third patient was a 50 years old Chinese man with hepatitis B virus infection presented with a single lesion in the liver and two enlarged lymph nodes. The patient received liver puncture before operation to indicate lymph node metastasis and had local recurrence after liver resection. The patient underwent chemotherapy and radiotherapy. The patient was diagnosed as lymphoepithelioma-like hepatocellular carcinoma. Finally, the patient died at 24 months follow-up. Conclusions: This article reports 3 cases of LELC and reviews the current research discovery, which suggests that even the locally advanced patients of LELC with postoperative recurrence and preoperative lymph node metastasis should be actively treated and intervened for a longer survival period. Keywords: Liver Cancer, Lymphoepithelioma-like carcinoma, Hepatocellular carcinoma, Cholangiocarcinoma