bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conventional angiography findings in hemodynamically unstable patients with acute abdominal hemorrhage and a negative CT bleeding study
Authors: O’Brien Amy C. , Healy Gerard M. , Rutledge Nicholas , Patil Aishan , McCann Jeffrey W. J. , Cantwell Colin P. 
Published: April 2020

Abstract
Background
CT bleeding study (CTA) is regularly requested in acute abdominal haemorrhage (AAH) with haemodynamic instability by clinical teams and interventional radiologists because CTA can; detect arterial bleeding at low rates of hemorrhage, accurately localize the bleeding point and characterize the etiology.
How best to manage an unstable patient who has an AAH with a haematoma and no acute vascular findings on CTA represents a difficult clinical scenario for treating physicians and Interventional Radiologists.

Purpose
To review the conventional angiography (CA) findings and clinical outcome of hemodynamically unstable patients with AAH who had a preceding negative CTA.

Materials and methods
All patients who were hemodynamically unstable and underwent CTA and CA for acute arterial abdominal hemorrhage at our institution between 01/01/2010 and 31/12/2017 were identified. Patients with obstetric, penetrating trauma, abdominal aortic or venous sources of hemorrhage were excluded. Patients who had a negative CTA before CA were included. Patient medical records were reviewed for clinical outcome.

Results
In the study period 160 hemodynamically unstable patients underwent 178 CA procedures. 155 CA procedures were preceded by CTA. 141 CTAs demonstrated active bleeding or an abnormal artery. 14 CTAs in 13 patients demonstrated hematoma but no acute bleeding (mean age = 56-years; M:F, 12:1). Eight of the 14 CA studies demonstrated: active bleeding (n = 4), pseudoaneurysm (n = 1) or a truncated artery (n = 3). Cases of renal hemorrhage demonstrated a significantly higher proportion of false negative CTA studies (36%). Selective (n = 8) or empiric (n = 4) embolization was performed in twelve cases. All patients stopped bleeding and there were no mortalities.

Conclusion
In a cohort of hemodynamically unstable patients, 57% (8/14) of cases with no acute vascular findings on CTA demonstrated a source of hemorrhage on CA. The false negative rate of CTA was significantly higher for renal tract hemorrhage compared to other sites of bleeding.
Screening and evaluation of reliable traits of upland cotton (Gossypium hirsutum L.) genotypes for salt tolerance at the seedling growth stage
Authors: SIKDER Ripon Kumar , WANG Xiangru , JIN Dingsha , ZHANG Hengheng , GUI Huiping , DONG Qiang , PANG Nianchang , ZHANG Xiling , SONG Meizhen 
Published: April 2020

Abstract
Background
Salt stress significantly inhibits the growth, development, and productivity of cotton because of osmotic, ionic, and oxidative stresses. Therefore, the screening and development of salt tolerant cotton cultivars is a key issue towards sustainable agriculture. This study subjected 11 upland cotton genotypes at the seedling growth stage to five different salt concentrations and evaluated their salt tolerance and reliable traits.

Results
Several morpho-physiological traits were measured after 10 days of salinity treatment and the salt tolerance performance varied significantly among the tested cotton genotypes. The optimal NaCl concentration for the evaluation of salt tolerance was 200 mmol·L− 1. Membership function value and salt tolerance index were used to identify the most consistent salt tolerance traits. Leaf relative water content and photosynthesis were identified as reliable indicators for salt tolerance at the seedling stage. All considered traits related to salt tolerance indices were significantly and positively correlated with each other except for malondialdehyde. Cluster heat map analysis based on the morpho-physiological salt tolerance-indices clearly discriminated the 11 cotton genotypes into three different salt tolerance clusters. Cluster I represented the salt-tolerant genotypes (Z9807, Z0228, and Z7526) whereas clusters II (Z0710, Z7514, Z1910, and Z7516) and III (Z0102, Z7780, Z9648, and Z9612) represented moderately salt-tolerant and salt-sensitive genotypes, respectively.

Conclusions
A hydroponic screening system was established. Leaf relative water content and photosynthesis were identified as two reliable traits that adequately represented the salt tolerance of cotton genotypes at the seedling growth stage. Furthermore, three salt-tolerant genotypes were identified, which might be used as genetic resources for the salt-tolerance breeding of cotton.
Prediction and in silico validation of MYH7 gene missense variants in the Iranian population: a bioinformatics analysis based on Iranome database
Authors: Shahbazi Shirin 
Published: April 2020

Abstract
Background
Identifying disease-causing genetic variants in a particular population improves the molecular diagnosis of genetic disorders. National genome databases provide valuable information on this matter. This study aimed to investigate the genomic variants of the MYH7 gene, related to the common heart disease, i.e., hereditary cardiomyopathy.

Results
MYH7 gene variants were extracted from the Iranome database and loaded into SPSS software. The filtration steps were performed based on the variant specification and with emphasis on identifying missense changes. Using predictive algorithms, different aspects of the changes such as allele frequency and functional defects were investigated. Our results showed that 41 (17.4%) coding variants were synonymous compared with 18 (7.7%) missense alterations. The missense variants were mostly observed in exons 20–40 that encode MyHC α-helical rod tail. The p.Pro211Leu, p.Arg787His, p.Val964Leu, p.Arg1277Gln, and p.Ala1603Thr were already known to be associated with inherited cardiomyopathy. Four of the missense variants, p.Asn1623Ser, p.Arg1588His, p.Phe1498Tyr, and p.Arg1129Ser, were located on MyHC α-helical rod tail and none of them was annotated on dbSNP or genomAD databases.

Conclusion
Our study showed several MYH7 variants associated with the disease in the Iranian population. The results emphasize the importance of analyzing the exons encoding MyHC α-helical rod tail. The investigation of genomic databases can be considered as a cost-effective strategy using targeted mutation detection analyses. The efficacy of this prediction method should be elucidated in further studies on patients’ cohorts.
Prevalence and predictors of urinary tract infection in full-term and preterm neonates
Authors: Mohamed Wael , Algameel Alkassem , Bassyouni Rasha , Mahmoud Abd el Tawab 
Published: April 2020

Abstract
Background
Early and prompt diagnosis of urinary tract infection (UTI) in neonates has important therapeutic implications. The aim of this study was to evaluate the prevalence of UTI in neonates admitted to a referral neonatal intensive care unit (NICU) and to identify predictors associated with an increased risk of UTI in NICU population.

Results
The prevalence of culture-proven UTI in the studied neonates was 6.67%. Moreover, UTI was more frequent (70%) among full-term neonates. Additionally, both fever and pyuria were the only clinical and laboratory findings that showed significant association with UTI (p < 0.05). Binary logistic regression revealed that neonates with pyuria in urine analysis were 5.44 times more liable to have UTI, while the presence of fever constitutes a risk of only 0.166 (odds ratios were 5.44 and 0.166, respectively). Additionally, sensitivity, specificity, positive predictive value, and negative predictive value of the regression model were 50.0, 94.5, 20.05, and 98.57%, respectively.

Conclusions
We conclude that UTI is not uncommon in full-term neonates admitted in NICU. Additionally, pyuria was significantly related to positive urine culture and its detection in urine analysis increases the likelihood of UTI by 5.44 times.
UNDERSTANDING THE DEADLIFT AND ITS VARIATIONS
Authors: Holmes Clifton J. 
Published: April 2020

Apply It!
From this article, the reader should:
• Understand what the deadlift exercise is and how it can be beneficial for anyone going through a resistance training program;
• Gain foundational knowledge about the similarities and differences between deadlift exercise variations;
• Be able to avoid the common errors associated with the deadlift exercises in order to stay safe and injury-free; and
• Know how to determine which deadlift exercise variation is best for a particular individual.
Synthesis of Metal–Curcumin Complex Compounds (M = Na⁺, Mg²⁺, Cu²⁺)
Authors: Peni Peni , Sasri Risya , Silalahi Imelda Hotmarisi 
Published: April 2020

Curcumin complex compound, MLn (L = curcumin; M = Na+, Mg2+, Cu2+) has been synthesized from the reaction between curcumin and metal precursors (NaCl, MgSO4.7H2O, CuCl2.2H2O) in ethanol under reflux conditions. Synthesis takes place through the reaction between the metal ions Na+, Mg2+, or Cu2+ as the central atom and curcumin as the ligand. Curcumin has been consumed after the reaction lasts for four hours, shown by thin-layer chromatography in which a new spot appears at higher Rf as the spot of curcumin disappears in the reaction mixture. Compared with the spectrum of curcumin, the FTIR spectra of the complexes show changes in the absorption bands and shifts of wave numbers particularly in absorption bands of phenolic –OH and C=O enol groups which strongly indicates the coordination of metal ions with the curcumin ligand which is proposed to be in β–1,3 diketone system. Also, the FTIR spectra of the reaction product showed typical absorption bands for the metal-oxygen group, M–O, at 524 cm–1, 670 cm–1 and 470 cm–1 in Na+–curcumin, Mg2+–curcumin and Cu2+–curcumin, respectively.
Antioxidant potential and identification of active compounds on Kabau seed (Archidendron bubalinum) flesh and husk extract
Authors: Rahmawati Fri , Kurniaty Linggom , Bintang Maria 
Published: April 2020

Kabau (Archidendron bubalinum) is one of the plants that is often used as food ingredients and has the potential to be developed in the health sector. This study aims to determine the antioxidant potential of kabau seeds using 2,2-diphenyl-1-picril hidrazil (DPPH) and ferric reducing ability power (FRAP) methods and to identify active compounds of kabau seeds using GC-MS. Kabau seeds were macerated using 70% ethanol and 99.9% ethanol. The results showed that 99.9% ethanol extract of kabau seed coat had the highest antioxidant activity with IC50 values of 26.75 ppm for the DPPH method and 121.55 ppm for the FRAP method, respectively. Identification of active compounds using GC-MS showed that 99.9% ethanol extract of kabau seed coat contained the most 9,12-octadecadienoic acid compounds (linoleic acid) so that it could be developed as an antioxidant.
Pemanfaatan Oktil Eugeniloksi Etanoat Hasil Sintesis sebagai Plasticizer Membran Polimer Cair Elektroda Selektif Ion
Authors: Lusiana Retno Ariadi , Siswanta Dwi 
Published: April 2020

Dua plasticizer, dibenzil eter (DBE) dan oktil eugeniloksi etanoat (OEE) dipelajari untuk mengetahui kemampuannya dalam membran polimer ESI (Elektroda Selektif Ion) perklorat dengan senyawa aktif TOMA-Cl (tetra oktil metil amonium klorida). Hasil penelitian menunjukkan dari hasil pengukuran terhadap karakteristik ESI perklorat didapatkan bahwa penggunaan DBE memberikan hasil yang lebih baik dibandingkan dengan OEE sebagai plasticizer. Secara umum, interaksi yang terjadi antara fasa membran dengan anion mengikuti kaedah seri Hofmeister.
Ekstraksi Campuran Logam Berat dan Pemisahan Cr(VI) dari Cr(III) Menggunakan Teknik Membran Cair Berpendukung (SLM)
Authors: Djunaidi Muhammad Cholid , Haris Abdul , Gunawan Gunawan 
Published: April 2020

Telah dilakukan penelitian tentang transport logam berat menggunakan SLM dengan senyawa pembawa. Pengukuran pH memperlihatkan ion hidrogen terlibat dalam transport ini. Penentuan konsentrasi logam berat menggunakan AAS dan spektrofotometer UV-Vis menunjukkan bahwa dalam larytan campuran, transport optimum logam berat dalam fasa penerima diperoleh dengan pembawa campuran 1:4 (TBP:D2EHPA 1M) dan pemisahan Cr(VI) dari Cr(III) dapat dilakukan dengan pembawa tunggal. Urutan transport logam berat dengan pembawa campuran 1:4 (TBP:D2EHPA) tersebut dalam larutan campuran dan limbah laboratorium adalah tCu(II) > tFe(III) > tNi(II. Pada pemisahan Cr dalam limbah penyamakan kulit, TBP dapat mengekstrak Cr(III) dan Cr(VI) sementara D2EHPA hanya mengekstrak Cr(III) sehingga Cr(III) dan Cr(VI) dapat dipisahkan
Supporting Digital Innovations By Interdisciplinary Entrepreneurial Learning
Authors: Hamburg Ileana 
Published: April 2020

Digitalization signifies transformational or disruptive implications of digital technologies for businesses (new business and work models, new types of products/services, new types of customer).
Digital technologies support new forms of innovation and entrepreneurial initiatives which hold implications at regional/national and societal and influence educators, policy making entities and other stakeholders.
The formation of the entrepreneur as a person for digital transformation is important and considered, in a large part, to be due to learning. Entrepreneurship is “a process of new value creation” and digital entrepreneurship is understood as “a subcategory of entrepreneurship in which some or all of what would be physical in a traditional organization has been digitized”.
Existing research on the digitalization of innovation and entrepreneurship refers mostly to specific fields or disciplines (e.g., marketing, economics, information systems, operations, strategy) and arguably, limited effort has been spent so far on adopting a more interdisciplinary view of the underlying issues. Disruptive innovation and entrepreneurs are strongly connected. Entrepreneurs are often the ones that develop new products or services that change an entire industry and disruptive innovation has the potential to improve student/employees outcomes also during their entrepreneurial education and training. Particularly it happens by breaking boundaries for an interdisciplinary entrepreneurial learning.
After the Introduction, the paper includes results of literature review and of interviews the author done with entrepreneurs within some European projects about different forms of innovation and entrepreneurship, particularly digital disruptive innovation and entrepreneurship.
A review of literature about entrepreneurial learning and basis components, which characterize it, are given in part 3. It includes also experience of the author in teaching and training entrepreneurs.
The last part of the paper presents some interdisciplinary new approaches within entrepreneurial learning oriented to disruptive, digital innovation and digital entrepreneurship. Developments within a European project with the participation of the author are also given.
Radiographic features of patients with chronic granulomatous disease
Authors: Kashani Paria , Farras Roca Lara , Manson David 
Published: April 2020

Introduction: Chronic granulomatous disease (CGD) is one of the most common primary immunodeficiencies of childhood, and is caused by defects in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. Alongside neutrophil dysfunction, dysregulation of the immune system predisposes patients to recurrent life-threatening infections as well as granuloma formation, hyperinflammation, and autoimmunity. Examination by imaging (radiography, ultrasound, computed tomography, magnetic resonance) in conjunction with biopsy and tissue or fluid cultures are essential to identify the extent and severity of infections as well as the microorganisms responsible. These modalities also help to guide the management of inflammatory complications.Aim: We highlight the common radiographic findings in 10 pediatric CGD patients followed at our centre over a period of 10 years.Methods: Medical records of patients with confirmed CGD diagnosis were reviewed retrospectively. All had low neutrophil oxidative burst index (NOBI) and pathogenic mutation in 1 of the 5 subunits of the NADPH oxidase. Three patients had autosomal recessive CGD and 7 had X-linked recessive CGD. All but 1 are male.Results: The most common radiographic presentation was hilar lymphadenopathy and pulmonary nodules. Other lung complications include cavitating lesions, lung abscess, pulmonary nodule, and pleuritic nodules. Lymphatic tissue and lymph nodes were involved in 50% of our cohort of patients, while gastrointestinal manifestations were noted in approximately 35% of our patients. These include the presence of pigmented macrophages, multiple granulomas, liver abscess, or detection of Aspergillus in tissue or fluid culture.Discussion: It is essential for clinicians to keep primary immunodeficiency as one of the differential diagnoses in patients who present with severe infection or inflammation. We encourage physicians to consider CGD in patients with above described findings and consider measuring NOBI in patients with early onset infection, inflammation, or granuloma formation.Statement of novelty: We describe the radiographic findings of a pediatric cohort of patients with CGD.
Injuries in Sprint Canoeists and Kayakers: Etiology, Mechanisms of Injury, Treatment Options, and Practical Applications
Authors: Pelham Thomas W. , Robinson Michael G. , Holt Laurence E. 
Published: April 2020

ABSTRACT
On-water and dry-land training programs for sprint canoeists and kayakers are physically demanding. Musculoskeletal injuries particularly to the shoulder, thoracic, and scapula regions are common. Overtraining can lead to muscle imbalances, glenohumeral and scapular kinematic dysfunctions, soft-tissue damage, and pain. Preventive programs are required. However, objective research-based evidence for sprint canoe- and kayak-specific preventive programming is lacking. This study will discuss common injuries sustained by paddlers, the mechanisms of these injuries, treatment and prevention approaches, and practical applications highlighting the need for coaches, clinicians, and strength and conditioning professionals to take a proactive approach in addressing high-risk injury factors. For a video abstract of this article, see Supplemental Digital Content 1, http://links.lww.com/SCJ/A275.
“There is nothing human in nature”
Authors: Manning Pascale M. 
Published: April 2020

Pascale M. Manning, “‘There is nothing human in nature’: Denying the Anthropocene in Richard Jefferies” (pp. 473–501)
This essay contends that the work of the nineteenth-century British writer and naturalist Richard Jefferies embodies both a recognition and a radical denial of the Anthropocene, expressing a nascent form of the ambivalence that stalks our contemporary recognitions and misrecognitions of the human in/and nature. Drawing upon a range of Jefferies’s writings—both his essays and his autobiography in addition to his fiction—it argues that there exists in Jefferies’s work a recurring vein of anti-ecological thought, particularly evidenced in the way it frequently depicts strict boundary lines, whether between agricultural and urban spaces, between civilization and wild nature, or between the human and the natural world. Taking issue with recent ecocritical accounts of Jefferies’s post-apocalyptic novel After London (1885), this essay rereads Jefferies’s novel in light of the wider range of his writings to argue that it is most usefully read not as a proto-ecological rebuke to the unsustainability of human agro-industrial practices, nor as a prophetic evocation of a world re-greened by the collapse of those practices, but rather as the irresolute culmination of a career spent both testifying to the essential inviolability of nature and bearing witness to the mounting evidence of anthropogenic rupture.
New records of ring nematodes, <i>Bakernema enormese</i> n. sp. and <i>Criconema</i> (<i>Nothocriconemella</i>) <i>graminicola</i> Loof, Wouts & Yeates, 1997 (Nematoda: Criconematidae) from natural forests of Vietnam
Authors: Chau Nguyen Ngoc 
Published: April 2020

Bakernema enormese sp. n., collected from rhizosphere of forest wood trees in Muong Phang, Dien Bien Province (north Vietnam) is described and illustrated. The new species is characterized by large body size and stylet. In general, this new species is close to two existing species of the same genus, B. inaequale and B. dauniense by cuticle structure in transparent membranous projections which appear in lateral view as spine-like structures on each annulus. These structure arranged into several rows along the body. In morphology, the new species differs from B. inaequale and B. dauniense by body and stylet length, i.e. 609–842 µm and 143.5–150 µm vs. 391–578 µm and 59–74 µm for B. inaequale and vs. 391–461 µm and 65–74 µm for B. dauniense. In addition, new species can be distinguished from B. inaequale by the longer membranous projection, 8–12 vs. 6–10 µm and vagina shape, curved vs. sigmoid. From B. dauniense, the new species differs by the much longer membranous projection, 8–12 vs. 1.4–2.2 µm and less number annules between vulva and tail end (RV), 3–4 vs. 7.8 annules. The presence of Criconema (Nothocriconemella) graminicola Loof, Wouts & Yeates, in Vietnam with morphometrics, illustrators and remarks given.
O Discurso Desinformativo sobre a Cura do COVID-19 no Twitter: Estudo de caso
Authors: Recuero Raquel , Soares Felipe 
Published: April 2020

O presente artigo analisa como se deu a circulação de desinformação a respeito de uma possível “cura” para o coronavírus no Twitter brasileiro em um período de dez dias de março de 2020. Seu foco é na discussão (1) dos modos através dos quais os discursos relacionados à desinformação sobre supostas curas da pandemia foram espalhados, (2) os diferentes tipos de discurso desinformativo e sua prevalência e (3) os modos de disputa contra os discursos que desmentem a desinformação. Através de um estudo de métodos mistos, com análise de conteúdo e análise de redes sociais de 57.295 mil tweets, observamos (1) o alinhamento do discurso da desinformação com o discurso político de apoio ao presidente da República, Jair Bolsonaro; (2) no espalhamento da desinformação associado à ação de influenciadores líderes de opinião notadamente alinhados à sua base de suporte; (3) o crescimento da circulação de desinformação a partir dos pronunciamentos do presidente; (4) a circulação de enquadramentos enganosos de informações verdadeiras como a estratégia-chave da disputa discursiva, buscando alinhar o discurso da “cura” com a desinformação.