bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review on the Role of Nanosensors in Detecting Cellular miRNA Expression in Colorectal Cancer
Authors: Girigoswami Koyeli , Girigoswami Agnishwar 
Published: May 2020

Background:
Colorectal cancer (CRC) is one of the leading causes of death across the
globe. Early diagnosis with high sensitivity can prevent CRC progression, thereby reducing the condition
of metastasis.

Objective:
The purpose of this review is (i) to discuss miRNA based biomarkers responsible for CRC,
(ii) to brief on the different methods used for the detection of miRNA in CRC, (iii) to discuss different
nanobiosensors so far found for the accurate detection of miRNAs in CRC using spectrophotometric
detection, piezoelectric detection.

Methods:
The keywords for the review like micro RNA detection in inflammation, colorectal cancer,
nanotechnology, were searched in PubMed and the relevant papers on the topics of miRNA related to
CRC, nanotechnology-based biosensors for miRNA detection were then sorted and used appropriately
for writing the review.

Results:
The review comprises a general introduction explaining the current scenario of CRC, the biomarkers
used for the detection of different cancers, especially CRC and the importance of nanotechnology
and a general scheme of a biosensor. The further subsections discuss the mechanism of CRC
progression, the role of miRNA in CRC progression and different nanotechnology-based biosensors so
far investigated for miRNA detection in other diseases, cancer and CRC. A scheme depicting miRNA
detection using gold nanoparticles (AuNPs) is also illustrated.

Conclusion:
This review may give insight into the different nanostructures, like AuNPs, quantum dots,
silver nanoparticles, MoS2derived nanoparticles, etc., based approaches for miRNA detection using
biosensors.
Serangga Pengunjung Bunga Yang Berpotensi Sebagai Vektor Penyakit Darah Pada Tanaman Pisang Di Kabupaten Sigli, Banda Aceh
Authors: Sahetapy Betty , Maryana Nina , Manuwoto Syafrida , Mutaqin Kikin H. 
Published: May 2020

Penyakit darah disebabkan oleh blood disease bacterium (BDB). Bakteri diduga dapat ditularkan melalui bibit yang terinfeksi, alat pertanian, tanah yang terbawa air, kontak akar dan serangga pengunjung bunga pisang. Penelitian ini bertujuan untuk mengetahui serangga pengunjung bunga yang berpotensi sebagai vektor dalam penyebaran penyakit darah pada tanaman pisang. Penelitian diawali dengan pengumpulan sampel serangga di Kecamatan Padang Tiji, Kabupaten Sigli, Propinsi Banda Aceh. Lokasi ini merupakan area endemik penyakit darah pisang. Identifikasi serangga dilakukan di Laboratorium Biosistematika Serangga, sedangkan isolasi dan identifikasi BDB dilaksanakan di Laboratorium Bakteriologi Tumbuhan, Departemen Proteksi Tanaman, Fakultas Pertanian, Institut Pertanian Bogor. Bakteri yang diisolasi dikonfirmasi dengan uji Gram, hipersensitif dan patogenisitas. Hasil penelitian menunjukkan bahwa serangga yang ditemukan di area pertanaman pisang Desa Capah Paloh 1, Capah Paloh 2, Simpang Betung 1, Simpang Betung 2 dan Pante Cermin adalah tergolong dalam ordo Diptera dan Hymenoptera. Drosophilidae (Diptera) ditemukan lebih dominan di antara serangga-serangga tersebut. BDB berhasil diisolasi dari seluruh tubuh serangga ordo Diptera (Drosophilidae, Tephritidae dan Muscidae) sehingga membuktikan bahwa serangga-serangga ini berpotensi sebagai vektor BDB.
Pengaruh senyawa volatil yang dihasilkan bakteri endofit asal padi terhadap Rhizoctonia oryzae dan Cercospora oryzae
Authors: Widiantini Fitri , Yulia Endah , Kurniawan Agung 
Published: May 2020

Penggunaan fungisida dalam mengendalikan penyakit pada tanaman telah banyak dilaporkan menimbulkan dampak negatif terutama terhadap lingkungan. Oleh karena itu diperlukan alternatif pengendalian lain yang lebih ramah lingkungan. Bakteri endofit telah banyak dimanfaatkan sebagai agens biokontrol pada berbagai penyakit tanaman karena dikenal sebagai sumber penghasil senyawa-senyawa yang bersifat antifungal. Laboratorium Bioteknologi Proteksi Tanaman Fakultas Pertanian Universitas Padjadjaran memiliki koleksi beberapa bakteri endofit hasil isolasi asal tanaman padi yang masih dalam tahap pengujian. Penelitian ini dilakukan dengan tujuan untuk mengetahui potensi antijamur dari senyawa volatil yang dihasilkan oleh bakteri endofit dalam menekan pertumbuhan jamur Rhizoctonia oryzae penyebab penyakit bercak pelepah daun dan jamur Cercospora oryzae penyebab penyakit bercak daun secara in vitro. Percobaan dilakukan dengan metode dual culture dengan menggabungkan dua cawan dimana isolat bakteri endofit dan jamur patogen ditumbuhkan secara terpisah. Hasil pengujian menunjukkan bahwa isolat bakteri endofit Os1 dan Os2 memiliki kemampuan terbaik dalam menghambat patogen R. oryzae dengan persentase penghambatan pertumbuhan masing-masing sebesar 68,7% dan 65,4%. Sedangkan isolat bakteri endofit Os3 adalah isolat bakteri endofit yang mempunyai kemampuan terbaik dalam menghambat perkembangan patogen C. oryzae dengan persentase penghambatan sebesar 87,1%. Pengamatan mikroskopis memperlihatkan bahwa senyawa volatil yang dikeluarkan oleh isolat-isolat bakteri endofit tersebut dapat menyebabkan terjadinya malformasi pada miselia jamur R. oryzae dan C. oryzae.
Arquitetura e consumo no Pós-Segunda Guerra Mundial: os paralelos Brasil-EU | Architecture and consumption in the post World War II: Brazil-US paralles
Authors: Janjulio Maristela Da Silva 
Published: May 2020

Nos anos 1950, na cidade de São Paulo e em outros grandes centros brasileiros, a arquitetura moderna conquista sua hegemonia e chega à classe média. Na revista “Casa e Jardim”, naquela mesma década, constitui-se uma arquitetura — voltada a essa camada —, com linguagem moderna a que nomeamos “bem viver”. O contexto em que surge o “bem viver” é o da modernização brasileira, nos anos da década de 1950, particularmente na metrópole paulistana, com transformações econômicas, sociais, políticas e culturais e o da ampliação da influência econômica, política e ideológica dos EUA. O modo de vida americano é visto como modelo. O “bem viver” também reflete esse aspecto, apresentando paralelos com a arquitetura do Good-Life Modernism, que se desenvolve ao final da Segunda Guerra, nos Estados Unidos, igualmente voltada à classe média. Ambas, Good-Life Modernism e “bem viver”, estão profundamente imbricadas com a questão do consumo e constituem cenário para uma vida confortável, moderna e prazerosa. Existem, ainda, similaridades entre as linguagens utilizadas nessas duas arquiteturas. O objetivo deste trabalho é investigar algumas analogias e as prováveis divergências entre ambas, Good-Life Modernism e “bem viver”, a respeito das questões do consumo e da linguagem utilizada. Esta pesquisa envolveu a revista “Casa e Jardim” da década de 1950, além de revistas americanas — algumas técnicas e outras voltadas ao público leigo.
Clinical, clinicopathologic, and hepatic histopathologic features associated with probable ketoconazole-induced liver injury in dogs: 15 cases (2015–2018)
Authors: Macho Luis P. , Center Sharon A. , Randolph John F. , Dumars Lee Ann , Rush Susan E. , Cameron Mary Kate , Lucy John M. , Hall-Fonte Deborah L. , McDonough Sean P. , Peters-Kennedy Jeanine , Marinoff Jacqueline , Harrison Jennifer , Sabatino Bethany , Deitz Krysta 
Published: May 2020

Abstract

OBJECTIVE
To characterize clinical, clinicopathologic, and hepatic histopathologic features and outcome for dogs with probable ketoconazole-induced liver injury.

ANIMALS
15 dogs with suspected ketoconazole-induced liver injury that underwent liver biopsy.

PROCEDURES
Medical record data were summarized regarding signalment, clinical signs, clinicopathologic and hepatic histopathologic findings, concurrent medications, ketoconazole dose, treatment duration, and outcome.

RESULTS
Median age and body weight were 8.2 years (range, 5 to 15 years) and 13.0 kg (28.6 lb; range, 8.2 to 38.0 kg [18.0 to 83.6 lb]), respectively. The most common breed was Cocker Spaniel (n = 5). All dogs received ketoconazole to treat cutaneous Malassezia infections. Median daily ketoconazole dose was 7.8 mg/kg (3.5 mg/lb; range, 4.4 to 26.0 mg/kg [2.0 to 11.8 mg/lb]), PO. Treatment duration ranged from 0.3 to 100 cumulative weeks (intermittent cyclic administration in some dogs); 6 dogs were treated for ≤ 10 days. Common clinical signs included lethargy, anorexia, and vomiting. All dogs developed high serum liver enzyme activities. Hepatic histopathologic findings included variable lobular injury, mixed inflammatory infiltrates, and conspicuous aggregates of ceroid-lipofuscin–engorged macrophages that marked regions of parenchymal damage. Five dogs developed chronic hepatitis, including 3 with pyogranulomatous inflammation. Of the 10 dogs reported to have died at last follow-up, survival time after illness onset ranged from 0.5 to 165 weeks, with 7 dogs dying of liver-related causes.

CONCLUSIONS AND CLINICAL RELEVANCE
Findings for dogs with hepatotoxicosis circumstantially associated with ketoconazole treatment suggested proactive monitoring of serum liver enzyme activities is advisable before and sequentially after initiation of such treatment.
Emergency tracheotomy and subsequent tracheal resection and anastomosis in a blue crane (Anthropoides paradiseus)
Authors: Yaw Taylor J. , Doss Grayson A. , Colopy Sara A. , Kincaid Anne L. , Hartup Barry K. 
Published: May 2020

Abstract

CASE DESCRIPTION
A 7-year-old female blue crane (Anthropoides paradiseus) was initially evaluated after it had suddenly developed signs of respiratory distress following aspiration of a rock. Emergency tracheotomy had been performed, and the rock had been removed from the proximal cervical portion of the trachea. Fifty-one days later, the clinical signs had returned and the crane was reevaluated.

CLINICAL FINDINGS
On reevaluation, no obvious external abnormalities were appreciated at the previous surgical site and no discharge was observed from the glottis. Computed tomography and tracheoscopy revealed marked tracheal stenosis and architectural collapse of the trachea at the previous surgery site.

TREATMENT AND OUTCOME
Tracheal resection and anastomosis was performed to remove the stenotic tracheal segment. Histologic examination of the resected tracheal segment revealed pyogranulomas with intralesional coccobacilli, fungal hyphae consistent with Aspergillus spp, possible parasitic ova, and features suggestive of mild to moderate heterophilic and lymphoplasmacytic tracheitis. The crane was treated with piroxicam, ceftiofur crystalline free acid, terbinafine, and itraconazole. At a follow-up examination 12 weeks later, no abnormalities were appreciated, and the surgical site had completely healed.

CLINICAL RELEVANCE
To the authors’ knowledge, this is the first reported case of successful tracheal resection and anastomosis in a bird of the order Gruiformes. The surgical approach used for the blue crane may be useful for removal of tracheal foreign bodies in this and other long-necked avian species.
Investigation of the effects of veterinarians’ attire on ratings of trust, confidence, and comfort in a sample of pet owners in Canada
Authors: Coe Jason B. , O'Connor Rachel , Pizzolon Christina N. , Hester Kimberly A. , Nogueira Borden Leandra J. , Haley Derek 
Published: May 2020

Abstract

OBJECTIVE
To examine companion animal owners’ perceptions of appropriate veterinarian attire and investigate potential associations between a veterinarian's attire and clients’ ratings of trust in, confidence in, and comfort with a veterinarian.

SAMPLE
449 pet owners.

PROCEDURES
Participants were randomly assigned to complete a questionnaire containing photos of a male or female model veterinarian photographed in 8 attire types (formal attire, white dress shirt with black pants, white casual shirt with khaki pants, surgical scrubs, white casual shirt with jeans, surgical scrub top with jeans, surgical scrub top with khaki pants, and white laboratory coat with khaki pants). Participants were asked to rate their trust in, confidence in, and comfort with the pictured individual on a response scale of 1 (low) to 7 (high), rank photos according to their preferences for attire, and provide input on the importance of attire and other appearance-related subjects. Attire and gender of photographed individual and participant demographics were investigated for associations with trust, confidence, and comfort scores.

RESULTS
Most (317/445 [71%]) respondents indicated veterinarians’ attire was important. Attire type was significantly associated with respondents’ trust, confidence, and comfort scores. Model veterinarian gender and participant education level were also associated with trust and comfort scores.

CONCLUSIONS AND CLINICAL RELEVANCE
Veterinarians’ attire is a form of nonverbal communication that is likely to inform clients’ first impressions and may influence clients’ trust in, confidence in, and comfort with a veterinarian. Veterinary personnel and veterinary management should consider how attire and general appearance represent staff members or their practice.
The Settlement Pattern of Rubber Plantation Areas from the Dutch-Indie’s Period in Bogor.
Authors: Hari Inagurasi Libra 
Published: May 2020

Abstrak. Tulisan ini dilatarbelakangi oleh pemikiran, bahwa Bogor merupakan sebuah daerah yang kaya akan potensi perkebunan masa Hindia Belanda. Meskipun demikian belum ada tulisanyang membahas seperti apa dan bagaimanakah pemukiman di kawasan perkebunan karet masa Hindia Belanda di Bogor. Dilatarbelakangi oleh pemikiran tersebut maka tulisan ini bertujuan menampilkan kembali gambaran pola pemukiman di kawasan perkebunan karet melalui jejak-jejak yang ditinggalkan. Tulisan ini disusun melalui tahap penelusuran literatur, survei arkeologi danlingkungan di lokasi penelitian, analisis, sintesa antara data arkeologi dan data sejarah. Gambaran pola pemukiman di kawasan perkebunan karet di Bogor dapat dibuktikan secara fisik melalui tinggalan-tinggalan arkeologi. Bangunan-bangunan yang berfungsi sebagai rumah tempat tinggal pemilik kebun,bangunan kantor perkebunan, pengolahan getah karet, dan mausoleum, serta artefak genteng lamadan botol Eropa merupakan petunjuk keberadaan pemukiman di perkebunan karet Hindia Belanda diBogor. Pola pemukiman perkebunan tersusun atas bangunan tempat tinggal pemilik kebun misalnya landhuis atau kantor perkebunan yang dikelilingi oleh tempat tinggal pegawai dan pekerjanya, tempat pengolahan karet. Adapun mausoleum ditempatkan berjauhan dari pusat pemukiman. Abstract. The Settlement Pattern of Rubber Plantation Areas from the Dutch-Indie’s Period in Bogor.This article is based on a notion that Bogor is an area rich in potency of plantations during the Dutch-Indie’s Period. However, there has not been an article that discusses what were the settlements in the rubber plantations in Bogor during the Dutch-Indie’s period like and how were life there at that time. Based on such thought, this article will reconstruct the settlement patterns in the rubber plantations through their remains, by conducting literature study, archaeological and environmental surveys in the research area, analyses, and synthesis between archaeological and historical data. The depiction of the settlement patterns in rubber plantations in Bogor can be physically proven through their archaeological remains. Buildings that were functioned as residences of plantation owners, administration building (plantation office), rubber-latex processing building, and mausoleum, as well as artefacts in forms of old roof tiles and European bottles are indications of the presence of settlements in Dutch Indie’s rubber plantations in Bogor. The settlement pattern consists of residence of plantation owner, known as landhuis, plantation office surrounded by residences of plantation workers, and rubber-latex processing building. Mausoleum is located far from the centre of settlement.
Analisa Sheetpile Pada Saluran PHB Inlet Rumah Pompa Taman Ratu
Authors: Imamuddin Muhammad 
Published: May 2020

Rumah Pompa Taman Ratu is located in Hilir Perumahan Taman Ratu Kota, West Jakarta Administration. In 2006 the construction of a pumping house was carried out to cope with flooding / inundation in the area downstream of the Taman Ratu connecting channel (PHB) with a capacity of 500 liters / second. The west and east sides of PHB Taman Ratu are inspection roads currently used by the community to access and exit the Taman Ratu Housing. The construction of the pump house does not have a flood gate due to limited land, so the pump must work every day to lower the water level at PHB Taman Ratu. Due to frequent rise and fall in elevation at Taman Ratu PHB, the PHB walls made of stone cause damage to several segments that can cause landslides. By doing soiltest using bore log and soiltest results analyzed using software, the PHB channel pouring is generated using Sheetpile type W400 A 1000 with a depth of 15 meters to resist landslides on the PHB Taman Ratu inspection road.
National Cultures and Politeness Strategies in Intercultural Communication Among Japanese and American Characters in “The Last Samurai” Movie: A Cross-Cultural Pragmatic Analysis
Authors: Nurilaila Eka , Ricahyono Sigit , Setyadi Dwi , Arifin Samsul 
Published: May 2020

<p>The study which is descriptive qualitative in nature, aims to investigate preference of politeness strategies by American and Japanese characters in “The Last Samurai movie and explain it in terms the national culture. Results show that the order of preference by Americans is: 1) BoP (11/50%), 2) PoP (7/31.8%), 3) NeP (3/13.6%), and 4) OfR (1/4.5%). That by the Japanese is: 1) OfR (18/60%), 2) BoR (6/20%), 3). NeP (6/20%), 4) PoP (0). American national culture and that of Japan which are different affect their preference of politeness strategies shown in “The Last Samurai” movie. In conclusion, language and culture affect each other. People coming from different language and culture communicate differently.</p>
Learning Translation and Multi-culture to Reduce Social Conflict
Authors: Wuryantoro Aris 
Published: May 2020

<p>This study aims to describe the role of learning translation with enhancing multi-culture understanding to reduce social conflict in society. This study used descriptive qualitative method by using documentation technique in collecting data. The source of the data are documentations in the form of intralingual and interlingual translation. The result of the study reveals that translation has four aspects, there are meaning, grammatical structure, communication situation, and cultural context. Besides, translation is closely related to cultural context aspect because translation contains at least cultural aspect from source language and target language. The researchers conclude that learning translation can enhance multi-culture in order to reduce social conflicts. The language used by one society automatically shows its language user or its social identity. The researcher concludes that by mastering language and culture of one society as a part of learning translation, we can reduce social conflict which mainly caused by misunderstanding toward the used language and culture. </p>
Prevalence of SUL(1,2), GYR(A, B) and OXA genes among multidrug resistance Klebsiella pneumoniae isolates recovered from women suffering urinary tract infection
Authors: Saaid Tuwaij Nabil Salim , Al-khilkhali Huda Jameel Baker , Mohsen Haneen Mohamed 
Published: May 2020

Klebsiella pneumoniae is a significant concern multidrug-resistant microorganism and a one common gram negative bacteria associated with infections of women urinary tract. Therefore, this work aimed to the molecular screening of Sul(1and 2), Gyr(A and B) and OXA genes among K. pneumoniae isolates in Najaf City, Iraq. Out of 250 urine specimens were collected from women showing symptoms of urinary tract infection during five months January to of May 2019, bacterial growth was157 isolates, included 133 gram negative compared with 24 gram positive bacteria while 98 specimens were no growth. According to the Vitek-2 system, 30 K. pneumoniae isolates were obtained.Data on current work revealed that the 26-35 age group was the highest 14 K. pneumoniae isolates. Results of antimicrobial susceptible recorded all isolates were multi-drug resistant (MDR) and they have a different range of resistance. However, all 30 isolates(100%) resistant to ampicillin drugs, while the lowest rate was 1(3.33%) forImipenemdrug. PCR assay revealed exist of oxa, sul-1, sul-2, gyr-A and gyr-B genes among K. pneumoniae isolates with rates 20(66.66%), 11(36.66%), 22(73.33%), 3(10%) and 17(56.66%) respectively.
Liver CT Image Processing And Diagnosing Using Artificial Neural Networks And MATLAB
Authors: Nguyen Thanh Minh Nhat , Tran Van Hoang Tien 
Published: May 2020

Segmentation is a grand challenge, and there are many contests are held around the world to solve this challenge, especially in the biomedical image. There are many solutions to solve this challenge have been published.Nowadays, neural networks, including deep learning is a powerful and state-of-the-art way to segment objects from the background. But to use deep learning effectively, besides design a good network architecture, the preparation of input data is also an important requirement. Active contour (another name: Snake) is a classical segmentation technique in image processing. But the accuracy of this technique is not as high as we need for health care problems, and soft techniques such as neural networks or deep learning can improve this problem. But in those researches, deep learning is supplied to change the parameters of the active contour algorithm.We propose a combination of two fields of solving segmentation problem, a classical one, and a modern: using data from active contour to be the input of deep learning. The images to be used in this research are human liver CT images.
Healing the third degree thermal burn in mice by Dielectric Barrier Discharge Plasma (DBD plasma): Comparison and evaluation of area, burn wound healing time, burn skin temperature
Authors: Ngo Thi Minh Hien , Do Tuyet Nhi , Nguyen Quoc Duy Nam , Nguyen Duy Phuong , Lam Nguyen Ngan Ha , Huynh Quang Linh 
Published: May 2020

Burns are one of the most devastating conditions encountered in medicine. This injury is in skin or other tissues, caused by heat-cold, electricity or chemicals [1,2]. There are lots of methods to treat burns and each method has its own advantages, such as medicine, dressing, low-level laser, plasma, skin graft surgery... [3].This study experimented with the 3rd degree burn model in mice by heat, treating by DBD plasma, is a non-invasive treatment and using clinical diagnostic methods by (1) normal image, (2) thermal image, (3) HE staining. Aim of this research is evaluation and comparison the area, temperature and wound healing time of non-invasive treatment with DBD plasma and nontreatment. After 3-week experiment, using diagnostic methods and analysis tools have demonstrated that the 3rd thermal burn wound healing of plasma treatment recovers faster than non-treatment about: (1) Burn wound surface shrinkage rate is higher: ~ 5%; (2) Healing time is faster: 2-3 days; (3) The average temperature of the burn wound is lower: 1-2oC. Therefore, DBD plasma is a potential treatment in burns wound and wound healing in the future. Keywords: DBD plasma, burn wound, healing wound