bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of neuroendocrine differentiation on the survival of patients diagnosed with pancreatic ductal adenocarcinoma
Authors: Kit O. I. , Franciyanc E. M. , Derizhanova I. S. , Karnaukhov N. S. , Kuznetsova M. A. , Voloshin M. V. , Trifanov V. S. , Aleinov V. I. 
Published: December 2020

Purpose of the study. Determine the frequency of MiNeN among pancreatic carcinomas and analyze the survival rate of patients depending on the percentage of cells with neuroendocrine differentiation in the tumor.Materials and methods. The current study included 31 patients with a pancreatic tumor who received surgical treatment at the Rostov Cancer Research Institute. An immunohistochemical study was conducted on biomarkers of chromogranin A, synaptophysin, and ki-67 for these patients. Based on the data obtained, 4 groups for neuroendocrine differentiation were identified.Results. The direct effect of neuroendocrine differentiation on the survival of patients with histologically confirmed pancreatic ductal adenocarcinoma has been proven. Among the sample of 31 patients, neuroendocrine differentiation was revealed in 24 cases (77%), of which 3 cases of MiNeN (10.3%) were detected. It is also proven relationship between neuroendocrine and patient survival, where an increase percent of positive cells in tumors (chromogranin A or synaptophysin) means a better prognosis. Chromogranin A is a more significant predictor of survival compared to synaptophysin. The largest difference in survival was between negative expression of chromogranin A and the presence of more than 1% positive cells in the tumor.Conclusion. We supposed that it is necessary to use neuroendocrine markers (chromogranin A and synaptophysin) in the diagnosis of ductal adenocarcinomas, even without histological signs of neuroendocrine differentiation. This will allow for a larger amount of data to determine their significance as prognostic markers.
Effect of Vermicompost Dose to K Content in Leaves and Growth of Corn (Zea mays, L) on Ultisol
Authors: Nurjanah Nunung , Riwandi Riwandi , Hasanudin Hasanudin 
Published: December 2020

The objectives of this research were to obtain an optimum dose of vermicompost fertilizer to the nutrient levels of K in the leaves, K uptake, and corn growth in ultisols. This research were held in September until November 2018, which has been implemented in green house and the Laboratory of Soil Science, Faculty of Agriculture, University of Bengkulu. The research used Completely Randomized Design (CRD) with a single factor consisting of 7 levels of treatment and three replicates i.e. 0 , 2.5 , 5.0 , 7.5 , 10.0, 12.5, and 15.0 ton ha-1. The results showed that the optimum dose of vermicompost fertilizer 5.71 ton ha-1, resulting in leave K content of 0.59%, 9.5 ton vermicompost ha-1, producing the absorption of K leaves 31 kg ha-1, 9.59 ton vermicompost ha-1, producing a plant height 160.7 cm, 10.2 ton vermicompost ha-1, producing the fresh stover weight 27,561.2 kg ha-1, 98.9 ton vermicompost ha-1, producing the dry stover weight 5,675.5 kg ha-1, and 9.5 tons vermicompost ha-1, producing root dry weight 1,156 kg ha-1.
Relationship Analysis of Soil Bulk Density, Available K, and Slope to Productivity of Salak Pondoh at Padang Jaya, North Bengkulu
Authors: Yakub Muhammad , Barchia M. Faiz , Suharjo Usman K.J. 
Published: December 2020

Salak (Zalacca edulis Gaertn. Voss) is one of the most populair native fruits of Indonesia, consumed as a table fruit by most Indonesians. However, the yield of salak pondoh grown in Bengkulu is still lower than that in their native soil Java, believed to have more suitable soil properties for growing salak pondoh. The objective of this research were to evaluate the relationship of soil bulk density, available K, and slope to the productivity of salak pondoh grown at Padang Jaya Regency, North Bengkulu. We did a survey to collect data on soil bulk density (BD), available K (K), and slope as well as the productivity of salak pondoh grown at Padang Jaya from November 2017 to May 2017. The results showed that there was a significant relationship between soil characteristics and salak productivity, as shown in a linear model of Y = 2.929 -1.070 BD + 0.069 K - 0.126 Slope. Soil K was positively correlated to salak productivity, suggesting that salak productivity increased with an increase in soil K. On the other than, soil bulk density and slope were negatively correlelated to salak productivity, indicating that salak productity decreased with an increase in slope and in soil bulk density.
Good Dances Make Good Guests: Dance, Animation and Sovereign Assertion in ‘Amis Country, Taiwan
Authors: Hatfield DJ W. 
Published: December 2020

Within the context of official multiculturalism and the promotion of tourism to improve the economic prospects of Taiwanese Indigenous people, ritual dances of ‘Amis/Pangcah people, known as malikoda, have become sites of conflict concerning ritual propriety and performance. Although as participatory practices, malikoda can never be performed for an audience, they have served to mediate outside power, including but not limited to ancestral spirits and political figures. However, whether and how those outside ‘Amis communities can malikoda remains subject to debate. Malikoda animates a model of Indigenous sovereignty, which can flexibly incorporate external forces that impinge on ‘Amis communities. Yet, the felicity conditions for malikoda are unstable. To resolve this, ‘Amis people have relied upon a combination of heritage and local discourses that define the dance as an act of hospitality. Both types require the alignment of various actors, media and interpretations at multiple scales, often obviating interpretation. Thus, attention to malikoda highlights how Indigenous people engage with indigeneity as a cultural resource under multiculturalism and raises broader questions about the role of animation in sovereign assertion.
Modern views on the role of main components of stroma and tumor microinvironment in invasion, migration and metastasis
Authors: Naleskina L.A. , Kunska L.M. , Chekhun V.F. 
Published: December 2020

Summary. The review presents modern ideas about tumor microenvironment, which most researchers recognize as the main “player” in tumor cell invasion, cell migration and metastasis. The current data on the main components of the stroma and the microenvironment, which play the role of the driving force in tumor progression, are analyzed. In particular, the review highlights the issues of origin, biological traits, phenotypic plasticity, functional heterogeneity of activated fibroblasts — myofibroblasts and tumor-associated fibroblasts, which in recent years have received much attention. Such components of the extracellular matrix proteome as collagen and matrix metalloproteinases are discussed in detail. They are mostly produced by activated fibroblasts and, on the one hand, initiate the development of desmoplasia due to type I collagen and, on the other hand, promote degradation of extracellular matrix proteins due to metalloproteinases, which generally leads to tissue remodeling that promotes tumor progression. Possibilities of using the most important indicators of extracellular matrix remodeling as potential markers and targets of clinical strategy are discussed.
Molecular phenotype of high-grade endometrioid carcinoma of the endometrium
Authors: Buchynska L.G. , Glushchenko N.M. , Nesina I.P. , Brieieva O.V. , Iurchenko N.P. 
Published: December 2020

Summary. Background: Prognosis of the course of tumor progression is one of urgent problems of clinical oncology. A relevant specificity of endometrial cancer is its clinical polymorphism within the same histological type of the disease. The search for molecular-biological features associated with the aggressive phenotype of endometrioid carcinomas is indisputably urgent. Aim: To study molecular-biological features of endometrioid carcinoma of the endometrium (ECE) and to identify the molecular subtype of tumors with high potential of malignancy. Materials and Methods: Surgical specimens of 127 patients with EC, stages I–II, aged 36–72 (the average age — 59.3 ± 3.2) were studied using morphological and immunohistochemical methods. The multivariant analysis with the Kullback’s informative measure and PanelomiX were used to estimate the significance of the expression of specific biomarkers. Results: The expression of a complex of multifunctional markers was evaluated in ECE cells of different malignancy stage: p53, FOXP3, p21WAF1/CIP1, р16INK4a, E2F1, cyclins Е and D1, Her2/neu, с-Myc, Е-cadherin, β-catenin, vimentin, CD44, CD24. A triad of biomarkers with threshold expression levels was determined (р53 > 45%; FOXP3 < 14%; с-Myc > 10%). The high expression of oncogene c-Myc and oncosuppressor p53 along with the low level of FOXP3 in tumor cells of ECE was associated with high proliferative potential, low differentiation grade, and deep invasion of a tumor into the myometrium. Conclusions: The molecular phenotype of ECE, most informative in terms of specificity and sensitivity (95%) — р53highFOXP3lowc-Mychigh, was first characterized, which would help identify a high-grade subtype of this cancer form.
İş Stres Düzeyinin Çalışanlarda Beslenme Durumu, Diyet Kalitesi ve Antropometrik Ölçümlere Etkisinin Değerlendirilmesi
Authors: Özcan Çiğdem , Kızıl Mevlüde 
Published: December 2020

Amaç: İş yaşamında stresin artması ile çalışanlarda depresyon ve kaygı gibi psikolojik; obezite ve kalp hastalıkları gibi fizyolojik zararlar oluşabilmektedir. Stresin, diyetteki sağlıksız seçimlerle ve iştah üzerindeki etkileriyle sağlık sorunlarına yol açabileceği ileri sürülmektedir. Bu çalışmada, iş stresi ve geriliminin beslenme durumu ve antropometrik ölçümler üzerine etkisinin değerlendirilmesi amaçlanmıştır.
Bireyler ve Yöntem: Araştırma, bir devlet üniversitesinde idari personel, temizlik personeli ve aşçı olarak çalışan 20-65 yaş arası 34 kadın ve 150 erkek ile yürütülmüştür. Bireylerin beslenme alışkanlıklarını, iş stres durumlarını belirlemek amacıyla anket formu uygulanmıştır. Bireylerin 24 saatlik besin tüketim kayıtları ile Sağlıklı Yeme İndeksi (SYİ) puanları hesaplanmış; antropometrik ölçümleri alınmıştır.
Bulgular: İş gerilimi olmayan ve SYİ puanı kötü düzeyde olanların oranı idari personelde daha düşük bulunmuştur. İş gerilimi olmadığı durumda da aşçıların %76.9’unun, temizlik personelinin %89.5’unun ve idari personelin %67.9’unun bel kalça oranlarının yüksek olduğu ve bu durumun obezite ile ilişkili hastalıklar açısından risk oluşturabileceği belirlenmiştir. İş gerilim durumuna göre temizlik personelinin yağ, posa, B1, B2, C vitamini, niasin, magnezyum ve demir alımları anlamlı bir fark göstermiştir (p<0.05). Temizlik personelinin yağ, posa alımları iş stresi puanı ile anlamlı negatif bir ilişki göstermiştir (p<0.05). İdari personelde ise iş stresi puanı, meyve suyu puanı ve sodyum puanı ile pozitif, sebze puanı, proteinli besin alım puanı ile negatif korelasyon göstermiştir. İdari personelin, iş yükü puanı beden kütle indeksi, bel çevresi ile negatif bir ilişki göstermiştir (p<0.05).
Sonuç: İş stresi bireylerin beslenme kalitelerini ve antropometrik ölçümlerini etkileyen bir faktördür. İş yerinde sağlıklı beslenme alışkanlıklarını kazandırmak ve iş stresini azaltmak için stratejilerin geliştirilmesi gereklidir.
The Adaptation of Professional Learning Activities Scale to Turkish: The Validity and Reliability Study
Authors: Polatcan Mahmut 
Published: December 2020

Öz
The purpose of this study is to adapt the Professional Learning Activities Scale (PLAS) developed by Geijsel, Sleegers, Stoel, and Krüger (2009) into Turkish through conducting the relevant validity and reliability analyses. This study followed the pathway recommended by Hambleton and Patsula (1999) for the adaptation process. The data we used came from a total of 256 teachers working in 16 pre-schools, primary and secondary schools located in the Karabuk and Istanbul provinces of Turkey. We performed Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) to test the construct validity of the Turkish-adapted form of the scale. In addition, Cronbach's Alpha coefficient was calculated for the reliability of the scale. The results of the study demonstrated that The Turkish Form of PLA is a reliable and valid instrument to evaluate the extent to which teachers are engaged in professional learning activities.
Anahtar Kelimeler
Professional learning activities scale,, adaptation, validity-reliability, teacher professional learning
STRATEGIES AND ROLE OF LOCAL GOVERNMENT IN IMPROVING THE COMPETITIVENESS OF TRADITIONAL FISHERMEN IN PANDEGLANG, BANTEN
Authors: Kusumajanti Kusumajanti , Widiastuti Ni Putu Eka , Kamaluddin Asep 
Published: December 2020

The aims of study to explore in depth: a. strategies and role of local government supports the formation of fishermen groups and group performance in enhancing the competitiveness of traditional fishermen; b. Strategies undertaken by local governments to improve competitiveness so as to realize the prosperity of traditional fishermen, c. group communication model between local government, traditional fishermen group, and partners This study use qualitative research methods with a critical paradigm referring to the critical concepts of Marxist thought. The results showed that the government through the Ministry of Marine Affairs and Fisheries Republic of Indonesia has issued Government Regulation no. 50 Year 2015 on empowering small fishermen and small fish farmers. The Ministry of Marine Affairs and Fisheries has an agenda to improve the welfare of traditional fishermen and to optimize their potentials in groups, which are handed down to the provincial and district fisheries departments. Pandeglang District Government as the object of research through Fisheries Department has the authority to manage, utilize, and conserve marine and fishery resources for the welfare of Pandeglang community, especially fisherman community, cultivation, processing and marketing of fish, and to increase contribution for PAD (District Owned Revenue). Fisheries Department develop strategies for improving the welfare of traditional fishermen, among others, encourage the formation of fishermen cooperatives with legal status. Socialization of the use of fishing gear which is not prohibited by the government. This is because there are still many traditional fishermen in Pandeglang who use Cantrang that can threaten the sustainability of marine ecosystems. The local government through related offices has not been actively involved in providing assistance to traditional fishermen so that they have high competitiveness such as maintaining good quality fish quality, stable catch quantity, environment of fishery and marine areas that is maintained so as to ensure the sustainability of existence fish in the sea. The results of this study have implications on the preparation of roles and strategies of local governments in improving the competitiveness of traditional fishermen adapted to local elements so that traditional fishermen become prosperous.
KEBERAGAMAN PARIWISATA DAN BUDAYA SEBAGAI IDENTITAS MASYARAKAT (Strategi Komunikasi Pemasaran Dinas Pariwisata, Pemuda dan Olahraga di Kota Singkawang)
Authors: Varanida Dea 
Published: December 2020

Sebagian besar setiap daerah di Indonesia saat ini telah menyadari akan pentingnya pariwisata untuk kemajuan dalam mengembangkan potensi daerahnya. Bukan hanya untuk memajukan pariwisata, namun juga untuk pertumbuhan ekonomi bagi masyarakat daerah tersebut. Kemudian dari pada itu, pariwisata juga sudah tidak seperti dahulu lagi namun semakin berkembang maknanya bukan hanya untuk berekreasi semata tapi sudah semakin luas artiannya. Pariwisata sudah menjadi kesatuan yang tidak bisa dipisahkan dari maysarakat dan sudah menjadi kebutuhan yang wajib untuk dilakukan. Maka dari itu melalui sektor pariwisata masing-masing daerah meningkatkan wisata alam maupun budaya untuk meningkatkan perekonomian. Metode yang digunakan dalam penelitian ini adalah dengan menggunakan metode deskriptif paradigma kualitatif melalui beberapa tahapan yaitu observasi pendahuluan, wawancara dan dokumentasi yang berkaitan dengan strategi komunikasi pemasaran yang dilakukan oleh Dinas Pariwisata, Pemuda dan Olahraga Kota Singkawang. Peneliti melakukan wawancara dengan beberapa narasumber yang sesuai untuk menjawab masalah penelitian. Hasil penelitian menunjukkan bahwa strategi komunikasi pemasaran yang dilakukan oleh Disparpora untuk mengembangkan sektor pariwisata dimulai dengan melakukan tahapan pendataan, perencanaan, dan pelaksanaan. Selanjutnya, terdapat media-media baru yang lahir dalam Komunikasi pemasaran yang dilakukan oleh komunikator maupun komunikan dalam mengembangkan promosi yang dilakukan yaitu dari pihak swasta maupun dari masyarakat sehingga melahirkan identitas dalam keberagaman pariwisata dan budaya yang ada di Kota Singkawang.
Implementasi Difusi Inovasi pada Kemampuan Media Baru dalam Membentuk Budaya Populer (Kajian pada Media Youtube di Kalangan Remaja)
Authors: Kartikawati Dwi 
Published: December 2020

Media massa merupakan salah satu medium komunikasi massa yang cukup kuat mempengaruhi para pemirsanya. Akibat dari perkembangan difusi dan inovasi atas isi media yang begitu kuat pengaruhnya maka terbentuklah budaya populer. Salahsatu media yang dimaksud adalah media youtube. Pengaruh media youtube sekarang bahkan turut dalam membentuk karakter, perilaku, hingga gaya hidup remaja pada umumnya. Karena dengan mempengaruhi perilaku serta karakter manusia menimbulkan sebuah realitas bagi masyarakat dengan melahirkan banyak opini-opini serta perubahan sosial yang disebabkan oleh media maka mendukung kuatnya budaya populer ini. Maka kajian ini membedah pada bagaimana implementasi difusi inovasi pada kemampuan media baru dalam membentuk budaya populer melalui youtube di kalangan remaja. Kerangka teoritis yang digunakan adalah Difusi Inovasi, Teori Budaya Populer dan Teori Konvergensi serta Media Baru. Metode yang dilakukan bersifat kualitatif deskriptif sehingga hasil kajian ini nantinya mengarah pada implementasi difusi inovasi dari media youtube di kalangan remaja dalam membentuk budaya populer serta proses dan perubahannya. Remaja memiliki kemampuan menyerap inovasi karena memiliki kemampuan adaptasi yang tinggi terhadap perubahan, memiliki kepercayaan, mampu berpikir rasional dan terbuka terhadap inovasi yang ada. Ciri yang melekat pada temuan jenis budaya populernya adalah bersifat tren, memiliki keanekaragaman bentuk, adapabilitas, durabilitas dan profitabilitas. Akan tetapi inovasi yang diserap para remaja selain membawa dampak positif juga memberikan dampak negatif.
Analisis Semiotika Logo Brodo Footweardi Media Sosial Twitter (Studi Analisis Semiotika Roland Barthes)
Authors: Sultanatta Canditra , Maryam Siti 
Published: December 2020

Seiring berkembangnya dunia periklanan, peran logo sangat penting sebagai identitas suatu produk. Tujuan Penelitian menganalisis makna logo Brodo Gentleman Footwear berdasarkan teori semiotika Roland Barthes Kajian Teoritis definisi konsep. Metode Penelitian yang digunakan adalah pendekatan kualitatif dengan jenis penelitian deskriptif. Pengumpulan Data dilakukan dengan melakukan depth interview, pengamatan dan studi pustaka. Hasil Penelitian menunjukan bahwa logo Brodo adalah teks ukiran Brodo dengan font yang membentuk silhouette ayam jago berwarna hitam dengan background putih. Tulisan Brodo begitu simple dan unik serta memberikan kesan kejantanan dan gagah yang berarti logo Brodo cukup menggambarkan identitas produk yang dijual, yaitu produk laki-laki yang gentlemen.kesimpulan: Logo Brodo ingin memperlihatkan bahwa logo tersebut cerminan dari pendiri Brodo, dan terdapat element fisik yang terdiri atas bentuk logo Brodo secara keseluruhan, Warna yang ada pada logo Brodo yaitu hitam dan putih, Teks yang terdapat di fisik logo yaitu “Brodo” yang dibuat menggunakan font gotham dan menggunakan warna dasar hitam pada tulisan Brodo dan warna putih pada background logo. Element non fisik dalam logo Brodo yang terdiri atas tujuan bahwa saat konsumen melihat logo tersebut akan selalu ingat cita rasa produk kebanggaan Indonesia, dan kegagahan produk Brodo. Dalam penelitian ini sesuai dengan teori semiotika Roland Barthes maka didapat makna yang terkandung dalam logo Brodo. Saran: Brodo dapat mempertahankan cita rasa fashion yang khas. Kata Kunci:Semiotika, Logo, Twitter, Roland Barthes.
Mobile Phone dan Media Sosial: Penggunaan dan Tantangannya pada Jurnalisme Online Indonesia
Authors: Puspita Ratna , Suciati Titis Nurwulan 
Published: December 2020

Artikel ini membahas mengenai tantangan jurnalis pada era mobile phone atau telepon seluler dan media sosial. Penulis berargumen, perubahan dan tantangan tidak hanya menyentuh organisasi media massa, kerja jurnalis atau wartawan, berita, khalayak, melankan juga nilai-nilai dan etika. Dengan melakukan kajian literatur dari penelitian-penelitian sebelumnya terkait perkembangan jurnalisme di Indonesia, penulis menyimpulkan media sosial tidak hanya berfungsi untuk medium promosi, melainkan medium menyampaikan berita pada era digital. Jurnalisme juga mengembangkan multimedia yang merujuk pada teknik presentasi atau penyajian berita yang memfokuskan pada tulisan dan gambar visual, baik bergerak maupun diam.
Performance of Supercritical CO2 Power Cycle and Its Turbomachinery with the Printed Circuit Heat Exchanger with Straight and Zigzag Channels
Authors: Saeed Muhammed , Alawadi Khaled , Kim Sung Chul 
Published: December 2020

Since printed circuit heat exchangers (PCHE) are the largest modules of a supercritical carbon dioxide Brayton cycle, they can considerably affect the whole system’s performance and layout. Straight-channel and zigzag-channel printed circuit heat exchangers have frequently been analyzed in the standalone mode and repeatedly proposed for sCO2−BC. However, the impact of heat exchanger designs with straight and zigzag-channel configurations on the performance of the cycle and its components, i.e., the turbine and compressor, has not been studied. In this context, this study evaluates the effect of different heat exchanger designs with various values of effectiveness (ϵ), inlet Reynolds number (Re), and channel configuration (zigzag and straight channel) on the overall performance of the sCO2−BC and its components. For the design and analysis of PCHEs, an in-house PCHE design and analysis code (PCHE-DAC) was developed in the MATLAB environment. The sCO2−BC performance was evaluated utilizing an in-house cycle simulation and analysis code (CSAC) that employs the heat exchanger design code as a subroutine. The results suggest that pressure drop in PCHEs with straight-channel configuration is up to 3.0 times larger than in PCHEs with zigzag-channel configuration. It was found that a higher pressure drop in the PCHEs with straight channels can be attributed to substantially longer channel lengths required for these designs (up to 4.1 times than zigzag-channels) based on the poor heat transfer characteristics associated with these channel geometries. Thus, cycle layouts using PCHEs with a straight-channel configuration impart a much higher load (up to 1.13 times) on the recompression compressor, this in turn, results in a lower pressure ratio across the turbine. Therefore, the overall performance of the sCO2−BC using PCHEs with straight-channel configurations is found to be substantially inferior to that of layouts using PCHEs with zigzag-channel configurations. Finally, optimization results suggest that heat exchanger’s design with inlet Reynolds number and heat exchanger effectiveness ranging from 32 k to 42 k and 0.94>ϵ>0.87, respectively, are optimal for sCO2−BC and present a good bargain between cycle efficiency and its layout size.