bluuebunny/crossref_metadata_2025_split huggingface dataset:
Restrictive eating, but not binge eating or purging, predicts suicidal ideation in adolescents and young adults with low‐weight eating disorders
Authors: Wang Shirley B. , Mancuso Christopher J. , Jo Jenny , Keshishian Ani C. , Becker Kendra R. , Plessow Franziska , Izquierdo Alyssa M. , Slattery Meghan , Franko Debra L. , Misra Madhusmita , Lawson Elizabeth A. , Thomas Jennifer J. , Eddy Kamryn T. 
Published: December 2019

AbstractObjectiveThis study examined the relationship between eating‐disorder behaviors—including restrictive eating, binge eating, and purging—and suicidal ideation. We hypothesized that restrictive eating would significantly predict suicidal ideation, beyond the effects of binge eating/purging.MethodsParticipants were 82 adolescents and young adults with low‐weight eating disorders. We conducted a hierarchical logistic regression, with binge eating and purging in Step 1 and restrictive eating in Step 2, to predict suicidal ideation.ResultsStep 1 was significant (p = .01) and explained 20% variance in suicidal ideation; neither binge eating nor purging significantly predicted suicidal ideation. Adding restrictive eating in Step 2 significantly improved the model (ΔR2 = .07, p = .009). This final model explained 27% of the variance, and restrictive eating (but not binge eating/purging) significantly predicted suicidal ideation (p = .02).DiscussionRestrictive eating is associated with suicidal ideation in youth with low‐weight eating disorders, beyond the effects of other eating‐disorder behaviors. Although healthcare providers may be more likely to screen for suicidality in patients with binge eating and purging, our findings indicate clinicians should regularly assess suicide and self‐injury in patients with restrictive eating. Future research examining how individuals progress from suicidal ideation to suicidal attempts can further enhance our understanding of suicide in eating disorders.
The difference in referencing in Web of Science, Scopus, and Google Scholar
Authors: Anker Markus S. , Hadzibegovic Sara , Lena Alessia , Haverkamp Wilhelm 
Published: December 2019

AbstractAimsHow often a medical article is cited is important for many people because it is used to calculate different variables such as the h‐index and the journal impact factor. The aim of this analysis was to assess how the citation count varies between Web of Science (WoS), Scopus, and Google Scholar in the current literature.MethodsWe included the top 50 cited articles of four journals ESC Heart Failure; Journal of cachexia, sarcopenia and muscle; European Journal of Preventive Cardiology; and European Journal of Heart Failure in our analysis that were published between 1 January 2016 and 10 October 2019. We recorded the number of citations of these articles according to WoS, Scopus, and Google Scholar on 10 October 2019.ResultsThe top 50 articles in ESC Heart Failure were on average cited 12 (WoS), 13 (Scopus), and 17 times (Google Scholar); in Journal of cachexia, sarcopenia and muscle 37 (WoS), 43 (Scopus), and 60 times (Google Scholar); in European Journal of Preventive Cardiology 41 (WoS), 56 (Scopus), and 67 times (Google Scholar); and in European Journal of Heart Failure 76 (WoS), 108 (Scopus), and 230 times (Google Scholar). On average, the top 50 articles in all four journals were cited 41 (WoS), 52 (Scopus, 26% higher citations count than WoS, range 8–42% in the different journals), and 93 times (Google Scholar, 116% higher citation count than WoS, range 42–203%).ConclusionScopus and Google Scholar on average have a higher citation count than WoS, whereas the difference is much larger between Google Scholar and WoS.
Tripodal Squaramide Derivative as a Neutral Chloride Ionophore for Whole Blood and Sweat Chloride Measurement
Authors: Fan Lingling , Xu Tingting , Feng Junjun , Ji Zihan , Li Le , Shi Xinhao , Tian Chunxiu , Qin Yu 
Published: December 2019

AbstractA tripodal squaramide derivative was synthesized and characterized as a new neural ionophore for chloride ion. Squaramide based compounds are known to be better hydrogen bonding receptors than urea derivatives because they donate four hydrogen bonds to anions, while the tripodal structure provides a 3D geometry optimum for spherical anion complexation. The ionophore demonstrated high selectivity over salicylate and heparin that are major interferences for chloride measurement in biological samples with direct potentiometric method. The new ionophore based solid‐contact electrodes were fabricated and showed the measuring range of 10−5 to 1 M chloride ion in the presence of 1 mM of salicylate and heparin with near Nernstian slope of 55 mV/decade. The sensor was successfully applied for the chloride measurement in undiluted heparinized whole blood and artificial sweat samples with our clinical analyzer.
Micro‐computed tomography imaging and probabilistic modelling of rock fracture by freeze–thaw
Authors: Maji Vikram , Murton Julian B. 
Published: December 2019

AbstractA major problem in studies of rock fracture by frost is the paucity of direct observations in space and time of the initiation and growth of microcracks and their transition to macrocracks. Such observations are essential to understand the location, timing and controls of rock fracture by freeze–thaw. The aim of the present work is to image and elucidate the early stages of rock fracture by applying imaging and statistical methods to a frost‐weathering experiment using intact specimens of a limestone (chalk) and sandstone. First, micro‐computed tomography (μ‐CT) is used to visualize rock fracture in three dimensions over the course of 20 freeze–thaw cycles and to estimate transverse strain using a pixel‐based approach. Second, probabilistic correlation functions are applied to quantify the progressive expansion of the fracture phase and associated damage to rock specimens. The method of μ‐CT is demonstrated for visualizing the growth and coalescence of microcracks and their transition to macrocracks. Fracture proceeded faster and to a greater extent in chalk relative to sandstone, and the macrocracks in chalk were mostly concentric and vertical. Both fracture development and positive transverse strain (dilation) accelerated after cycle 15, suggesting that a threshold has been exceeded, after which macrocracks were evident. Of three probabilistic correlation functions applied to the μ‐CT results, the modified lineal‐path function – which measures the continuous connectivity of the fracture phase in a specific direction – reveals that damage was more extensive in the chalk than the sandstone. It also allows a novel approach to define and quantify three zones of microcracking during freeze–thaw cycling of anisotropic rock: (1) the zone of inherent flaws; (2) the zone of active microcracking; and (3) the zone of weak influence during microcracking. The broader significance of this work is that it provides a new approach to investigate mechanistically how frost action damages rock. © 2019 John Wiley & Sons, Ltd.
A comprehensive review of heat transfer intensification methods for latent heat storage units
Authors: Elarem Raja , Alqahtani Talal , Mellouli Sofiene , Askri Faouzi , Edacherian Abhilash , Vineet Tirth , Badruddin Irfan Anjum , Abdelmajid Jemni 
Published: December 2019

AbstractLatent heat thermal energy storage (LHTES) systems and their applications have been very substantive for the developments in energy science and engineering. The efficiency of LHTES systems largely depends on the thermal conductivity of the phase change materials (PCMs) and the heat transfer mechanisms in them. This review focuses on the methods employed to enhance heat transfer in LHTES systems which accordingly improve their storage performance. This includes the possible geometrical configurations of LHTES systems and the effects of their design parameters. The various methods adopted for enhancing LHTES systems' performance through either applying nanomaterials additives, using cascaded or encapsulated PCMs, or employing extended surfaces, such as fins, are discussed in detail. Additionally, various designs of PCM based heat exchangers with active and passive heat transfer techniques were highlighted. These systems are critically analyzed to help selecting reliable techniques and compatible materials for effective designs in order to achieve more efficient LHTES systems. This review would be helpful for the researchers to further develop heat transfer intensification mechanisms in LHTES systems.
Fatty acid profile and in vitro biological properties of two Rosacea species (Pyrus glabra and Pyrus syriaca), grown as wild in Iran
Authors: Hazrati Saeid , Govahi Mostafa , Mollaei Saeed 
Published: December 2019

AbstractThe high demands for the consumption of edible oils have caused scientists to struggle in assessing wild plants as a new source of seed oils. Therefore, in this study, the oil yield, fatty acid and tocopherol compositions, antioxidant and antibacterial activities of the oils obtained from Iran's two endemic plants (Pyrus glabra and Pyrus syriaca) were investigated. The obtained oil yields from the P. glabra and P. syriaca seeds were 33 ± 0.51 and 26 ± 0.28 w/w%, respectively. Oleic acid (C18:1) with the amount of 49.51 ± 1.05% was the major fatty acid in the P. glabra oil, while the main fatty acids in the P. syriaca seed oil belonged to linoleic acid (C18:2) and oleic acid (C18:1) with the amounts of 46.99 ± 0.37 and 41.43 ± 0.23%, respectively. The analysis of tocopherols was done by HPLC, and the results indicated that the P. glabra and P. syriaca seed oils were rich in α‐tocopherol (69.80 ± 1.91 and 45.50 ± 1.86 mg/100 g oil, respectively), constituting 86.24 and 89.01% of total detected tocopherols, respectively. The study on the reducing capacity of the oils indicated that the P. glabra oil had more reducing capacity than the P. syriaca oil. Moreover, the antioxidant activity of the P. glabra seed oil (43.4 ± 0.7 µg/ml) was higher than the P. syriaca seed oil (46.3 ± 1.2 µg/ml). Also, the investigation of the antibacterial activities indicated that the P. glabra and P. syriaca oils have an inhibitory effect on the studied bacteria. The results indicate that the oils of these plants can be appropriate sources of plant oils which can act as natural antibacterial agents.
First Year Research Experience (FYRE): Bringing Research to New Undergraduates
Authors: Seifert Tricia A. , Oliveri Christiane , Shaw Colin A. 
Published: December 2019

AbstractThis chapter details the First Year Research Experience (FYRE) program at Montana State University, describing the intent and design of the program, as well as how FYRE participants differed in their approaches to learning from non‐participants.
Structure and dynamics of global capital and international trade: Analysis of the relationship between exports and foreign direct investment (FDI) from 2001 to 2006
Authors: Xiong Tingting , Sun Hao 
Published: December 2019

AbstractThis article attempts to explore the empirical evidence for the linkage between exports and foreign direct investment (FDI) by examining its relationship with over 140 countries from 2001 to 2006. Through using the comprehensive bilateral cross‐country panel exports and FDI data set for the first time, this article provides more insights about the relationships between exports and FDI with developed–developed country pairs as well as with developed–developing country pairs, respectively. By applying augmented gravity models, this article justifies that exports and FDI are complementary as previous studies posit. Furthermore, such complementary relationship is more positive and significant with developed–developing country pairs when compared to other combinations (developed–developed and developing–developing pairs). To be more specific, FDI from developed to developing countries promotes more exports, while FDI from developed countries to developed countries is less important in promoting exports.
Comparison of tris(2‐ethylhexyl) phosphate and di(2‐ethylhexyl) phosphoric acid toxicities in a rat 28‐day oral exposure study
Authors: Pelletier Guillaume , Rigden Marc , Wang Gen Sheng , Caldwell Don , Siddique Shabana , Leingartner Karen , Kosarac Ivana , Cakmak Sabit , Kubwabo Cariton 
Published: December 2019

AbstractTris(2‐ethylhexyl) phosphate (TEHP, CAS no. 78‐42‐2) is a plasticizer and a flame retardant, while di(2‐ethylhexyl) phosphoric acid (DEHPA, CAS no. 298‐07‐7) is an oil additive and extraction solvent. Publicly‐available information on repeated exposure to these two related organophosphate compounds is fragmentary. Hence, adult male and female Fischer rats were exposed to TEHP (300, 1000 and 3000 mg/kg body weight [BW]/day) or DEHPA (20, 60 and 180 mg/kg BW/day) by gavage for 28 consecutive days, to assess and compare their toxicities. Although significantly impaired BW gains and evidence of TEHP enzymatic hydrolysis to DEHPA were observed only in males, exposures to the highest TEHP and DEHPA doses often resulted in similar alterations of hematology, serum clinical chemistry and liver enzymatic activities in both males and females. The squamous epithelial hyperplasia and hyperkeratosis observed in the non‐glandular forestomach of rats exposed to the middle and high DEHPA doses were most likely caused by the slightly corrosive nature of this chemical. Although tubular degeneration and spermatid retention were observed only in the testes of males exposed to the highest TEHP dose, numerous periodic acid‐Schiff stained crystalline inclusions were observed in testis interstitial cells at all TEHP dose levels. No‐observed‐adverse‐effect levels for TEHP and DEHPA are proposed, but the lower serum pituitary hormone levels resulting from TEHP and DEHPA exposures and the perturbations of testicular histology observed in TEHP‐treated males deserve further investigation. Improved characterization of the toxicity of flame retardants will contribute to better informed substitution choices for legacy flame retardants phased‐out over health concerns.
Involvement of the Gut Microbiota and Barrier Function in Glucocorticoid-Induced Osteoporosis
Authors: Schepper Jonathan D , Collins Fraser , Rios-Arce Naiomy Deliz , Kang Ho Jun , Schaefer Laura , Gardinier Joseph D , Raghuvanshi Ruma , Quinn Robert A , Britton Robert , Parameswaran Narayanan , McCabe Laura R 
Published: December 2019

ABSTRACT
Glucocorticoids (GCs) are potent immune-modulating drugs with significant side effects, including glucocorticoid-induced osteoporosis (GIO). GCs directly induce osteoblast and osteocyte apoptosis but also alter intestinal microbiota composition. Although the gut microbiota is known to contribute to the regulation of bone density, its role in GIO has never been examined. To test this, male C57/Bl6J mice were treated for 8 weeks with GC (prednisolone, GC-Tx) in the presence or absence of broad-spectrum antibiotic treatment (ABX) to deplete the microbiota. Long-term ABX prevented GC-Tx-induced trabecular bone loss, showing the requirement of gut microbiota for GIO. Treatment of GC-Tx mice with a probiotic (Lactobacillus reuteri [LR]) prevented trabecular bone loss. Microbiota analyses indicated that GC-Tx changed the abundance of Verrucomicobiales and Bacteriodales phyla and random forest analyses indicated significant differences in abundance of Porphyromonadaceae and Clostridiales operational taxonomic units (OTUs) between groups. Furthermore, transplantation of GC-Tx mouse fecal material into recipient naïve, untreated WT mice caused bone loss, supporting a functional role for microbiota in GIO. We also report that GC caused intestinal barrier breaks, as evidenced by increased serum endotoxin level (2.4-fold), that were prevented by LR and ABX treatments. Enhancement of barrier function with a mucus supplement prevented both GC-Tx–induced barrier leakage and trabecular GIO. In bone, treatment with ABX, LR or a mucus supplement reduced GC-Tx–induced osteoblast and osteocyte apoptosis. GC-Tx suppression of Wnt10b in bone was restored by the LR and high-molecular-weight polymer (MDY) treatments as well as microbiota depletion. Finally, we identified that bone-specific Wnt10b overexpression prevented GIO. Taken together, our data highlight the previously unappreciated involvement of the gut microbiota and intestinal barrier function in trabecular GIO pathogenesis (including Wnt10b suppression and osteoblast and osteocyte apoptosis) and identify the gut as a novel therapeutic target for preventing GIO. © 2019 American Society for Bone and Mineral Research.
Maternal Transmission Ratio Distortion of GNAS Loss-of-Function Mutations
Authors: Snanoudj Sarah , Molin Arnaud , Colson Cindy , Coudray Nadia , Paulien Sylvie , Mittre Hervé , Gérard Marion , Schaefer Elise , Goldenberg Alice , Bacchetta Justine , Odent Sylvie , Naudion Sophie , Demeer Bénédicte , Faivre Laurence , Gruchy Nicolas , Kottler Marie-Laure , Richard Nicolas 
Published: December 2019

ABSTRACT
Pseudohypoparathyroidism type 1A (PHP1A) and pseudopseudohypoparathyroidism (PPHP) are two rare autosomal dominant disorders caused by loss-of-function mutations in the imprinted Guanine Nucleotide Binding Protein, Alpha Stimulating Activity (GNAS) gene, coding Gsα. PHP1A is caused by mutations in the maternal allele and results in Albright's hereditary osteodystrophy (AHO) and hormonal resistance, mainly to the parathormone (PTH), whereas PPHP, with AHO features and no hormonal resistance, is linked to mutations in the paternal allele. This study sought to investigate parental transmission of GNAS mutations. We conducted a retrospective study in a population of 204 families with 361 patients harboring GNAS mutations. To prevent ascertainment bias toward a higher proportion of affected children due to the way in which data were collected, we excluded from transmission analysis all probands in the ascertained sibships. After bias correction, the distribution ratio of the mutated alleles was calculated from the observed genotypes of the offspring of nuclear families and was compared to the expected ratio of 50% according to Mendelian inheritance (one-sample Z-test). Sex ratio, phenotype of the transmitting parent, and transmission depending on the severity of the mutation were also analyzed. Transmission analysis was performed in 114 nuclear families and included 250 descendants. The fertility rates were similar between male and female patients. We showed an excess of transmission from mother to offspring of mutated alleles (59%, p = .022), which was greater when the mutations were severe (61.7%, p = .023). Similarly, an excess of transmission was found when the mother had a PHP1A phenotype (64.7%, p = .036). By contrast, a Mendelian distribution was observed when the mutations were paternally inherited. Higher numbers of females within the carriers, but not in noncarriers, were also observed. The mother-specific transmission ratio distortion (TRD) and the sex-ratio imbalance associated to PHP1A point to a role of Gsα in oocyte biology or embryogenesis, with implications for genetic counseling. © 2019 American Society for Bone and Mineral Research.
Heterojunction of BiPO4/BiOBr photocatalysts for Rhodamine B dye degradation under visible LED light irradiation
Authors: Zhao Hong‐jian , Wu Ren‐Jang , Wang Xu‐Cheng , An Yu‐min , Zhao Wen‐Xia , Ma Fu 
Published: December 2019

AbstractBiOBr synthesized by alcoholysis precipitation is used in the preparation of BiPO4/BiOBr composites by adding H3PO4. Pristine BiOBr and a series of BiPO4/BiOBr composites have been successfully synthesized using an entirely room‐temperature production process. X‐ray powder diffraction, scanning electron microscopy, High‐resolution transmission electron microscopy, X‐ray photoelectron spectroscopy, UV–vis absorption spectroscopy were used to investigated the bulk structure, surface morphology, element composition and optical properties of the samples. The degradation effect of different proportions of BiPO4/BiOBr composites, BiOBr and BiPO4 on Rhodamine B (RhB) was evaluated under visible LED light irradiation. Compared to pure BiOBr and BiPO4, the as‐synthesized BiPO4/BiOBr composites showed enhanced performance, with 30% BiPO4/BiOBr composite showing the best performance, as it could degrade 95.66% of RhB (100 ml, 15 mg/L) within 120 min. The enhanced photocatalytic activity of BiPO4/BiOBr was attributed to the heterojunction formation between BiOBr and BiPO4 and efficient charge separation.
Sodium 4‐amino‐5‐hydroxy‐7‐sulfonaphthalene‐2‐sulfonate an efficient ligand for click reaction in water: Synthesis of 1,2,3‐triazole pharmacophore linked‐quinazolinone scaffold
Authors: Keivanloo Ali , Bakherad Mohammad , Mokhtarei Lotfollah 
Published: December 2019

AbstractWater soluble sodium 4‐amino‐5‐hydroxy‐7‐sulfonaphthalene‐2‐sulfonate ligand was used successfully for the preparation of 1,2,3‐triazoles pharmacophore linked‐quinazolinone scaffold. The reaction of ethyl 4‐oxo‐3,4‐dihydroquinazoline‐2‐carboxylate and related amide compounds with propargyl bromide afforded ethyl 4‐oxo‐3‐(prop‐2‐yn‐1‐yl)‐3,4‐dihydroquinazoline‐2‐carboxylate and its amide derivatives. The reaction of propargylated compounds with azides catalyzed by copper (II) salt, in the presence of Sodium 4‐amino‐5‐hydroxy‐7‐sulfonaphthalene‐2‐sulfonate as a ligand in water produced novel 1,2,3‐triazole pharmacophore linked‐quinazolinone‐4‐one scaffold with high‐to‐excellent yields. The ligand assisted in the click reaction and reduced loading of copper salt to 2 mol%. Simplicity, short reaction times, use of water as green solvent, and low catalyst loading are the main advantages of this procedure.
Histology and structural integration of the major morphologies of the Cypriniform Weberian apparatus
Authors: Bird Nathan C. , Abels Jeremy R. , Richardson Selena S. 
Published: December 2019

AbstractThe Weberian apparatus, a diagnostic feature of otophysan fishes, is a novel hearing adaptation integrating several developmental and morphological systems (ear‐vertebral column‐swim bladder). Otophysan fishes are one of the largest and most successful freshwater clades, with over 10,000 species across most continents. The largest otophysan order, Cypriniformes, dominates the freshwaters of Asia, Europe, North America, and Africa. Spanning such a wide variety of environments, the Weberian apparatus undergoes morphological modifications to maintain functionality. Within Cypriniformes, we propose three distinct morphological classes of the Weberian apparatus based on the level of skeletal expansion around the swim bladder: simple (typical of most Cyprinidae), anterior plate (found in families such as Gyrinocheilidae, Catostomidae, and Botiidae), and encapsulated (either single‐capsule as found, e.g., in Gobionidae and Cobitidae, or double‐capsule as found, e.g., in Nemacheilidae and Balitoridae). Little ontological or comparative data exists regarding the construction or integration of these different morphologies, and less is known about the tissue level integration and variation within these morphologies. We used paraffin histology to document the hard and soft tissue anatomy of the Weberian apparatus in six species representing all morphological classes. We found sites of similarity across the morphologies including size and structure of the saccule, aspects of ossicle ossification, and swim bladder tunica composition, indicating potential sites of developmental and functional constraint. In contrast, we found differences across both auditory and nonauditory features in otic chamber size, ossification within ossicles and other vertebral elements, and composition of ligaments, indicating likely sites of adaptability. Some of these changes are likely evolutionary (taxonomic), but may be influenced by the environmental niche occupied by the clade. These results show a clear need for increased ontological and comparative study of the complete cypriniform Weberian apparatus, particularly histologically, as well as increased auditory studies across morphological types.