bluuebunny/crossref_metadata_2025_split huggingface dataset:
Promoting Mental Health in School—Young People from Scotland and Sweden Sharing Their Perspectives
Authors: Kostenius Catrine , Gabrielsson Sebastian , Lindgren Eva 
Published: December 2019

AbstractThe rate of mental ill health has increased among children and youth during the past decade in Scotland and Sweden. School is important in influencing both health and education. The starting point for health promotion in school involves those who are affected, the students. The aim of this study was to describe and understand how mental health can be promoted in school from the perspective of young people. A total of 14 Scottish and Swedish young people aged 15–21, 11 girls and 3 boys from 3 municipalities, participated in 4 focus groups. The phenomenological analysis resulted in one main theme: Everyone is being there for each other encompassing three themes without any relative order of precedence: being in a safe, inclusive, and well-informed space; meeting adults who are available, listening, and taking action; and feeling significant and being of significance to others. Based on these findings, we suggest the following aspects to be essential when aiming to promote mental health in schools: (1) value and appreciate young people’s experiences, (2) view everyone in school regardless of age or profession to be an important piece in the mental health promotion puzzle by adopting a “whole school approach,” (3) foster a listening culture that focuses on building enabling relationships, (4) promote health and learning simultaneously to increase health literacy, (5) educate about mental health to minimize stigma and increase confidence in taking appropriate action.
Neuroprotective Effects of Doxycycline in the R6/2 Mouse Model of Huntington’s Disease
Authors: Paldino Emanuela , Balducci Claudia , La Vitola Pietro , Artioli Luisa , D’Angelo Vincenza , Giampà Carmela , Artuso Vladimiro , Forloni Gianluigi , Fusco Francesca R. 
Published: December 2019

AbstractMechanisms of tissue damage in Huntington’s disease involve excitotoxicity, mitochondrial damage, and inflammation, including microglia activation. Immunomodulatory and anti-protein aggregation properties of tetracyclines were demonstrated in several disease models. In the present study, the neuroprotective and anti-inflammatory effects of the tetracycline doxycycline were investigated in the mouse model of HD disease R6/2. Transgenic mice were daily treated with doxycycline 20 mg/kg, starting from 4 weeks of age. After sacrifice, histological and immunohistochemical studies were performed. We found that doxycycline-treated R6/2 mice survived longer and displayed less severe signs of neurological dysfunction than the saline-treated ones. Primary outcome measures such as striatal atrophy, neuronal intranuclear inclusions, and the negative modulation of microglial reaction revealed a neuroprotective effect of the compound. Doxycycline provided a significantly increase of activated CREB and BDNF in the striatal neurons, along with a down modulation of neuroinflammation, which, combined, might explain the beneficial effects observed in this model. Our findings show that doxycycline treatment could be considered as a valid therapeutic approach for HD.
Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene
Authors: Gawel Kinga , Turski Waldemar A. , van der Ent Wietske , Mathai Benan J. , Kirstein-Smardzewska Karolina J. , Simonsen Anne , Esguerra Camila V. 
Published: December 2019

AbstractTheCACNA1Agene encodes the pore-forming α1 subunit of voltage-gated P/Q type Ca2+channels (Cav2.1). Mutations in this gene, among others, have been described in patients and rodents suffering from absence seizures and episodic ataxia type 2 with/without concomitant seizures. In this study, we aimed for the first time to assess phenotypic and behavioral alterations in larval zebrafish with partialcacna1aaknockdown, placing special emphasis on changes in epileptiform-like electrographic discharges in larval brains. Whole-mount in situ hybridization analysis revealed expression ofcacna1aain the optic tectum and medulla oblongata of larval zebrafish at 4 and 5 days post-fertilization. Next, microinjection of two antisense morpholino oligomers (individually or in combination) targeting all splice variants ofcacna1aainto fertilized zebrafish eggs resulted in dose-dependent mortality and decreased or absent touch response. Over 90% knockdown ofcacna1aaon protein level induced epileptiform-like discharges in the optic tectum of larval zebrafish brains. Incubation of morphants with antiseizure drugs (sodium valproate, ethosuximide, lamotrigine, topiramate) significantly decreased the number and, in some cases, cumulative duration of epileptiform-like discharges. In this context, sodium valproate seemed to be the least effective. Carbamazepine did not affect the number and duration of epileptiform-like discharges. Altogether, our data indicate thatcacna1aaloss-of-function zebrafish may be considered a new model of absence epilepsy and may prove useful both for the investigation ofCacna1a-mediated epileptogenesis and for in vivo drug screening.
Decolorization of Rhodamine B dye by using multiwalled carbon nanotubes/Co–Ti oxides nanocomposite and Co–Ti oxides as photocatalysts
Authors: Zada Noor , Saeed Khalid , Khan Idrees 
Published: December 2019

AbstractFunctionalized multiwalled carbon nanotubes (F-MWCNTs)/Co–Ti oxide nanocomposites and neat Co–Ti oxide nanoparticles were synthesized by chemical reduction method. The scanning electron microscopy micrographs show that the bimetallic NPs in F-MWCNTs/Co–Ti are present in dispersed form while the neat Co–Ti nanoparticles were found in agglomerated form. The formation of nanocomposites and neat Co–Ti nanoparticles was also confirmed by energy-dispersive X-ray. Both types of nanocomposites were employed as photocatalyst for the photodegradation of Rhodamine B in aqueous medium under UV light irradiation. The photodegradation study was performed via UV–Vis spectrophotometer. The photodegradation results show that F-MWCNTs/Co–Ti oxide NPs degraded about 93.35% dye within 150 min irradiation time while the neat Co–Ti oxide NPs degraded about 91.76% dye within same irradiation time. The F-MWCNTs/Co–Ti can be easily removed and recycled due to its bulky composite nature as compared to neat Co–Ti oxide NPs. The effect of dye concentration, catalyst dosage, pH of medium and activity of recycled catalyst was also evaluated.
K2Ti6O13 Nanoparticle-Loaded Porous rGO Crumples for Supercapacitors
Authors: Lee Chongmin , Kim Sun Kyung , Chang Hankwon , Jang Hee Dong 
Published: December 2019

AbstractOne-dimensional alkali metal titanates containing potassium, sodium, and lithium are of great concern owing to their high ion mobility and high specific surface area. When those titanates are combined with conductive materials such as graphene, carbon nanotube, and carbon nanofiber, they are able to be employed as efficient electrode materials for supercapacitors. Potassium hexa-titanate (K2Ti6O13, KTO), in particular, has shown superior electrochemical properties compared to other alkali metal titanates because of their large lattice parameters induced by the large radius of potassium ions. Here, we present porous rGO crumples (PGC) decorated with KTO nanoparticles (NPs) for application to supercapacitors. The KTO NP/PGC composites were synthesized by aerosol spray pyrolysis and post-heat treatment. KTO NPs less than 10 nm in diameter were loaded onto PGCs ranging from 3 to 5 µm. Enhanced porous structure of the composites was obtained by the activation of rGO by adding an excessive amount of KOH to the composites. The KTO NP/PGC composite electrodes fabricated at the GO/KOH/TiO2 ratio of 1:3:0.25 showed the highest performance (275 F g−1) in capacitance with different KOH concentrations and cycling stability (83%) after 2000 cycles at a current density of 1 A g−1.
Are essay mills committing fraud? A further analysis of their behaviours vs the 2006 fraud act (UK)
Authors: Draper Michael J. , Reid-Hutchings Callum 
Published: December 2019

AbstractMany strategies have been proposed to address the supply of bespoke essays and other assignments by companies often described as ‘Essay Mills’ with the act of supply and use being invariably described as ‘contract cheating’. These proposals increasingly refer to the law as a solution in common with other action. In this article, the lead author revisits work undertaken in 2016 as a result of recent legal and extra-legal developments to assess whether the UK Fraud Act (2006) might now be used to tackle some of the activities of the companies involved, by comparing their common practises, and their Terms and Conditions, with the Act. It was previously found that all sites have disclaimers regarding the use of their products but there were some obvious contradictions in the activities of the sites which undermined those disclaimers, for example plagiarism-free guarantees for the work. In this article, we ask and consider the question whether this is still the case having regard to the impact of a change in the law by the UK supreme court and recent action of the UK Advertising Standards Authority. We also consider whether a call for a new offence to be created which specifically targets the undesirable behaviours of these companies is still justified.
Water as method: Explorations of locally situated environmental issues together with preschool children
Authors: Elkin Postila Teresa 
Published: December 2019

AbstractThe aim of this article is to show how water emerged as a research method nearby and within a small stream during a 9-month fieldwork carried out with preschool children. The fieldwork was informed and shaped by the preschool children’s and researcher’s situated knowledges and their questions about environmental issues concerning water, absence of water, pollution and ethics. The empirical material consists of films and photos, drawings and field notes, produced together by the preschool children and the researcher during the research. The analysis draws on relational ontology and the writings of Isabelle Stengers and Donna Haraway. The article concludes with a discussion about what can be learnt from the study and its contribution to research within the fields of Early Childhood Education and Environmental Education.
Regulating rude: Tensions between free speech and civility in academic employment
Authors: Cortina Lilia M. , Cortina Michael G. , Cortina José M. 
Published: December 2019

AbstractThis article addresses the tensions between calls for civility and rights to free speech in public academic employment. We begin by summarizing relevant organizational science on workplace incivility. Next come critical perspectives from other fields, asserting that civility appeals infringe on rights to freedom of expression. Following this is a review of key court decisions within the jurisprudence of free speech in the workplace, especially as it applies to academics. We also address the protections afforded by tenure and (at some institutions) unions. Bringing these streams of scholarship together, we expose predicaments faced by public universities seeking to cultivate safe and civil work environments while, at the same time, respecting faculty rights to free speech. We conclude by suggesting compromises between these conflicting aims that would allow organizations (in academia and beyond) to protect workforce dignity without infringing on the rights of reasonable people.
Work: What is it good for? (Absolutely nothing)—a critical theorist’s perspective
Authors: Mumby Dennis K. 
Published: December 2019

AbstractThe title of this focal article (unashamedly paraphrased from Edwin Starr’s classic 1970 antiwar song) is only partly intended to be tongue in cheek; work is a strange thing with a very checkered history. For the most part, it is something we take for granted. Most able-bodied adults work. Working hard is taken as a sign of being an upstanding citizen. Right wing politicians even insist that “government handouts” only be made available in exchange for participation in “workfare” programs. Moreover, work is not just something we do; over the last 100 years or so, it has become a defining, constitutive feature of who we are as human beings. Our very sense of identity and well-being is tied up with our relationship to work. It is no accident, after all, that the first question we ask a stranger is, “What do you do?” (and we are not asking about their hobbies); we see this question as a way of taking the measure of that person.
CEO Values, Firm Long-Term Orientation, and Firm Innovation: Evidence from Chinese Manufacturing Firms
Authors: Zheng Wei , Shen Rui , Zhong Weiguo , Lu Jiangyong 
Published: December 2019

ABSTRACTInnovation contributes to a firm's long-term competitive advantages but also involves significant risk and uncertainty. As agency theory predicts, CEOs are self-interested and risk-averse, and thus are reluctant to engage in innovation investments. However, the extent to which CEOs are self-interested and the mechanisms through which self-interested CEOs affect firm innovation have not been empirically tested. To fill this gap, we propose that CEOs possess a mix of both self-preserving and other-regarding motives, and build a mediation model in which CEO values affect firm innovation via firms’ long-term orientation. Based on a three-phase (from 2014 to 2016) survey of 436 Chinese manufacturing firms, we find that CEOs with high self-regarding values reduce innovation efforts and performance by damaging a firm's long-term orientation. Moreover, CEO tenure, CEO duality, and environmental uncertainty weaken the relationship between CEO values and firm innovation via long-term orientation. Our study enriches the innovation literature by extending the basic assumptions of agency theory and by providing empirical evidence to determine whether and how self-regarded CEOs affect firm innovation.
Landscape changes in the southern Amazonian foreland basin during the Holocene inferred from Lake Ginebra, Beni, Bolivia
Authors: Escobar-Torrez Katerine , Ledru Marie-Pierre , Ortuño Teresa , Lombardo Umberto , Renno Jean-François 
Published: December 2019

AbstractOur study is located in northern Beni and aims to improve knowledge on regional landscape changes from the last 8600 years, based on pollen and charcoal analyses from a lacustrine sediment core from Lake Ginebra. Our results showed that gallery forest and lacustrine sediment were observed from 8645 until 3360 cal yr BP. After a change from a lacustrine to a swamp environment at 1700 cal yr BP, the Cerrados and the Mauritia swamp became installed 1000 years ago on our study site. The environmental changes we observed over the last 8600 years in the Ginebra record reinforce the evidence of a west–east climatic gradient with the persistence of rain forest throughout the Holocene on the western side and the presence of the Cerrados until the late Holocene on the eastern side. Moreover, the persistence of a wet forest in the early to mid-Holocene in southwestern Amazonia highlighted some local responses to the global trend that could be related to the distance from the Andes; while in the late Holocene, both an increase in insolation and strengthening of the South American summer monsoon system enabled the installation of a seasonal flooded savanna in northern Beni and of the rain forest in eastern Beni.
Phylogenetic characterisation of seven Unicapsula spp. (Myxozoa: Myxosporea: Multivalvulida) from commercial fish in southern China and Japan
Authors: Li Ying-Chun , Tamemasa Souhei , Zhang Jin-Yong , Sato Hiroshi 
Published: December 2019

AbstractThe myxozoan genus Unicapsula Davis, 1924 (Myxosporea: Multivalvulida: Trilosporidae) is characterized as having one functional polar capsule (PC) and two rudimentary PCs in a three-valved myxospore. The plasmodia of Unicapsula spp. grow either in the myofibres or in the gills, oesophageal walls and urinary organs of marine fish. Few studies have investigated the taxonomy of Unicapsula spp. including the type species Unicapsula muscularis. Accordingly, the taxonomy of the genus was explored in the present study by using 15 new isolates of seven Unicapsula spp. (U. muscularis, U. galeata, U. andersenae, U. pyramidata, U. pflugfelderi, and two new species) that had formed pseudocysts in the trunk myofibres of commercial fish collected in southern China and Japan from November 2015 to January 2019. Two new species Unicapsula trigona n. sp., and Unicapsula motomurai n. sp. exhibited unique myxospore morphologies (semi-triangular and spherical myxospores, respectively) and 18S and 28S rDNA sequences that were distinct from those of the other Unicapsula spp. Phylogenetic analysis of the 18S and 28S rDNA sequences confirmed the monophyletic status of Unicapsula.
A NEW SHOCK MODEL WITH A CHANGE IN SHOCK SIZE DISTRIBUTION
Authors: Eryilmaz Serkan , Kan Cihangir 
Published: December 2019

AbstractFor a system that is subject to shocks, it is assumed that the distribution of the magnitudes of shocks changes after the first shock of size at least d1, and the system fails upon the occurrence of the first shock above a critical level d2 (> d1). In this paper, the distribution of the lifetime of such a system is studied when the times between successive shocks follow matrix-exponential distribution. In particular, it is shown that the system's lifetime has matrix-exponential distribution when the intershock times follow Erlang distribution. The model is extended to the case when the system fails upon the occurrence of l consecutive critical shocks.
Early weight trends after congenital heart surgery and their determinants
Authors: Banerji Nayan , Sudhakar Abish , Balachandran Rakhi , Sunil Gopalraj Sumangala , Kotayil Brijesh P. , Krishna Kumar Raman 
Published: December 2019

AbstractBackground:Early weight trends after cardiac surgery in infants from low- and middle-income countries where the majority are undernourished have not been defined. We studied the early post-operative weight trends to identify specific factors associated with early weight loss and poor weight gain after discharge following congenital heart surgery in consecutive infants undergoing cardiac surgery at a referral hospital in Southern India.Methods:This was a prospective observational study. Weights of the babies were recorded at different time points during the hospital stay and at 1-month post-discharge. A comprehensive database of pre-operative, operative, and post-operative variables was created and entered into a multivariate logistic regression analysis model to identify factors associated with excessive early weight loss after cardiac surgery, and poor weight gain following hospital discharge.Results:The study enrolled 192 infants (mean age 110.7 ± 99.9 days; weight z scores − 2.5 ± 1.5). There was a small but significant (p < 0.001) decline in weight in the hospital following surgery (1.6% decline (interquartile range −5.3 to +1.7)); however, there was substantial growth following discharge (26.7% increase (interquartile range 15.3–41.8)). The variables associated with post-operative weight loss were cumulative nil-per-oral duration and cardiopulmonary bypass time, while weight gain following discharge was only associated with age.Conclusion:Weight loss is almost universal early after congenital heart surgery and is associated with complex surgery and cumulative nil-per-oral duration. After discharge, weight gain is almost universal and not associated with any of the perioperative variables.
A review of predictive, prognostic and diagnostic biomarkers for brain tumours: towards personalised and targeted cancer therapy
Authors: Osei Ernest , Walters Pascale , Masella Olivia , Tennant Quinton , Fishwick Amber , Dadzie Eugenia , Bhangu Anmol , Darko Johnson 
Published: December 2019

AbstractBackground:Brain tumours are relatively rare disease but present a large medical challenge as there is currently no method for early detection of the tumour and are typically not diagnosed until patients have progressed to symptomatic stage which significantly decreases chances of survival and also minimises treatment efficacy. However, if brain cancers can be diagnosed at early stages and also if clinicians have the potential to prospectively identify patients likely to respond to specific treatments, then there is a very high potential to increase patients’ treatment efficacy and survival. In recent years, there have been several investigations to identify biomarkers for brain cancer risk assessment, early detection and diagnosis, the likelihood of identifying which group of patients will benefit from a particular treatment and monitoring patient response to treatment.Materials and methods:This paper reports on a review of 21 current clinical and emerging biomarkers used in risk assessment, screening for early detection and diagnosis, and monitoring the response of treatment of brain cancers.Conclusion:Understanding biomarkers, molecular mechanisms and signalling pathways can potentially lead to personalised and targeted treatment via therapeutic targeting of specific genetic aberrant pathways which play key roles in malignant brain tumour formation. The future holds promising for the use of biomarker analysis as a major factor for personalised and targeted brain cancer treatment, since biomarkers have the potential to measure early disease detection and diagnosis, the risk of disease development and progression, improved patient stratification for various treatment paradigms, provide accurate information of patient response to a specific treatment and inform clinicians about the likely outcome of a brain cancer diagnosis independent of the treatment received.
Erotic Use of Social Media Pornography in Gratifying Romantic Relationship Desires
Authors: Arikewuyo Abdulgaffar , Ozad Bahire , Lasisi Taiwo Temitope 
Published: December 2019

Abstract
The advent of social media platforms has revolutionized the process of information creation, dissemination and consumption. Although highly debated, pornography consumption on social media is a reality. Building on an acquisition, activation, and application model, this study investigates student’s (n = 379) gratification in romantic relationships as an outcome of their pornography consumption on social media, through the mediating effect of sexual confidence and sexual compulsivity. PROCESS macro was used to analyze the data. Results indicate that the effect of pornography consumption on a viewer’s gratification in a romantic relationship is partially mediated by sexual confidence (β = .0461, p < .001) and sexual compulsivity (β = .420, p < .001). These findings hold important contributions to current literature. Findings also indicate that pornography consumption positively and significantly aids a viewer’s sexual gratification in romantic relationships.
The South Korean Twin Registry
Authors: Hur Yoon-Mi , Kang Man Chull , Jeong Hoe-Uk , Kang Il Cook , Kim Jong Woo 
Published: December 2019

AbstractThe South Korean Twin Registry (SKTR) is an ongoing nationwide volunteer registry of South Korean twins and their families. Since its inception, from preschooler to young adult, twins have been registered with the SKTR and have demonstrated that relative influences of genetic and environmental factors explaining individual differences in various psychological, mental health and physical traits in South Koreans are similar to those found in many Western twin studies. Currently, studies at the SKTR focus on identification of the process of gene-by-environment interactions as well as developmental differences in genetic and environmental influences on psychological and mental health traits in South Koreans. This report provides a brief overview, recruitment strategies, current samples, zygosity assessment, measures and future directions of the SKTR.