bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phubbing, uso problemático de teléfonos móviles y de redes sociales en adolescentes y déficits en autocontrol
Authors: Álvarez Menéndez María , Moral Jiménez María de la Villa 
Published: May 2020

En la sociedad digital se están desarrollando hábitos comunicativos que interfieren en los vínculos interpersonales de interacción cara a cara y que están asociados al uso de dispositivos móviles. Objetivos. Evaluar el uso problemático que los adolescentes realizan de sus teléfonos móviles y de las redes sociales y en qué medida esos usos/abusos predicen el fenómeno social del Phubbing. Asimismo, se pretende analizar las relaciones existentes entre este comportamiento y los déficits en autocontrol. Metodología. Mediante un muestreo no probabilístico de conveniencia, se han seleccionado 285 estudiantes (167 chicas y 118 chicos) con edades comprendidas entre los 14 y los 18 años (M = 15.73; DT = 1.204). Resultados. Se ha hallado una baja prevalencia de abuso del móvil por parte de los adolescentes y se ha confirmado que el uso problemático del teléfono móvil y de las redes sociales predicen el phubbing. Se ha comprobado que las chicas hacen un mayor uso desadaptativo del teléfono móvil y de las redes sociales. También se constata una relación positiva entre el uso problemático de tales dispositivos y la conducta de phubbing asociado a los déficits en autocontrol. Conclusiones. Resulta necesario promover usos responsables de las TIC, así como de optimizar los recursos de interacción comunicativa de los adolescentes.
Perspectives from primary health care providers on supporting adolescents and young adults with chronic conditions transitioning to adult care: A descriptive qualitative study
Authors: Schraeder Kyleigh , Dimitropoulos Gina , McBrien Kerry , Li Jessica (Yijia) , Samuel Susan 
Published: May 2020

Abstract

Background: Transitioning from pediatric care to adult-oriented care at age 18 (the age of transfer in most countries and jurisdictions) is a complex process for adolescents and young adults affected by chronic physical health and/or mental health conditions. The role of primary health care providers for this population is poorly understood. Perspectives from these providers, such as family physicians and other members of the primary care team, have not been explored in depth. Methods: A total of 18 participants (e.g., family physicians, social workers, nurses) were recruited from 6 Primary Care Networks in Calgary, Alberta, Canada. Semi-structured individual interviews were conducted, and transcribed verbatim. A qualitative description approach was used to analyze the data, and included thematic analysis. Results: Five distinct, yet overlapping, roles of primary health care providers for adolescents and young adults transitioning to adult care resulted from our analysis: (1) being the “common thread” (continuous accessible care); (2) caring for the “whole patient” (comprehensive care); (3) “knowing families” (family-partnered care); (4) “empowering” adolescents and young adults to develop “personal responsibility” (developmentally-appropriate care); and (5) “quarterbacking” care (coordination of specialist and/or community-based care). Participants identified potential benefits of these roles for adolescents and young adults transitioning to adult care, and barriers in practice (e.g., lack of time, having minimal involvement in pediatric care). Conclusions: Input from family physicians, who follow their patients across the lifespan and provide the majority of primary care in Canada, are critical for informing and refining recommended transition practices. Our findings provide insights, from PHC providers themselves, to bolster the rationale for primary care involvement during transitions from pediatric specialty and community-based care for AYAs. Solutions to overcome barriers for integrating primary care and specialty care for adolescents and young adults need to be identified, and tested, with input from key stakeholders.
Obstructive Sleep Apnea: Evaluation of high risk individuals, knowledge and associated factors among a representative sample of Lebanese adults
Authors: Choucair Aurélie , Malaeb Diana , Hallit Souheil , Dagher Elissar 
Published: May 2020

Abstract
Background: To date, there has been no large population-based study about Obstructive Sleep Apnea (OSA) in Lebanon. Our study evaluated high risk individuals, knowledge and associated factors of OSA among a representative sample of Lebanese adults. Methods: A cross-sectional study, conducted between June and August 2019, enrolled 472 people aged above 18. A proportionate random sample from all Lebanese Governorate was applied. Each governorate is divided into Caza (stratum), which in turn is divided into multiple villages. Two villages were selected randomly from the list of villages provided by the Central Agency of Statistics in Lebanon. Households were randomly selected from each village using an online software.Results: The percentage of physician-diagnosed sleep apnea in our sample was 11%; 159 (33.7%) had poor knowledge (scores ≤11), whereas 165 (35.0%) and 148 (31.4%) had moderate (scores between 12 and 15) and good (scores ≥16) knowledge respectively. The study results showed that -according to the Epworth Scale- having diabetes mellitus, myocardial infarction, arrhythmia, and hypertension were associated with higher daytime sleepiness. Furthermore, mild, moderate and severe excessive daytime sleepiness (EDS) percentages were 14.4%, 16.3% and 13.8% respectively. According to the STOP-BANG questionnaire, 31.6% of participants had an intermediate risk of OSA and 7.6% had a high risk. Diabetic patients and those with myocardial infarction were significantly associated with higher STOP BANG scores.Concerning knowledge, having heard about sleep apnea was associated with a higher knowledge score. Overall, 31.4% of the participants had a good score. Conclusion The actual study proves that EDS which has adverse health effects, is associated with multiple morbidities. Besides, the general population isn’t aware enough of this disease. Comparing the rate of high-risk individuals to the physician-diagnosed ones, we conclude that in Lebanon, OSA is likely prevalent but underdiagnosed. Ongoing health campaigns and screenings should be assigned to target the general community.
Brief Evidence-Based Interventions for Universal Child Health Services: a restricted evidence assessment of the literature
Authors: Newham James J , McLean Karen , Ginja Samuel , Hurt Lisa , Molloy Carly , Lingam Raghu , Goldfeld Sharon 
Published: May 2020

Abstract
Background: Universal child health services (UCHS) provide an important pragmatic platform for the delivery of universal and targeted interventions to support families and optimize child health outcomes. We aimed to identify brief, evidence-based interventions for common health and developmental problems that could be potentially implemented in UCHS. Methods: A restricted evidence assessment (REA) of electronic databases and grey literature was undertaken covering January 2006 to August 2019. Studies were eligible if (i) outcomes related to one or more of four areas: child social and emotional wellbeing (SEWB), infant sleep, home learning environment or parent mental health, (ii) a comparison group was used, (iii) universal or targeted intervention were delivered in non-tertiary settings, (iv) interventions did not last more than 4 sessions, and (v) children were aged between 2 weeks postpartum and 5 years at baseline. Results: Seventeen studies met the eligibility criteria. Of these, three interventions could possibly be implemented at scale within UCHS platforms: (1) a universal child behavioural intervention which did not affect its primary outcome of infant sleep but improved parental mental health, (2) a universal screening programme which improved maternal mental health, and (3) a targeted child behavioural intervention which improved parent-reported infant sleep problems and parental mental health. Key lessons learnt include: (1) Interventions should impart the maximal amount of information within an initial session with future sessions reinforcing key messages, (2) Child SEWB Interventions should see the family as a holistic unit by considering the needs of parents with an emphasis on identification, triage and referral, and (3) Brief interventions may be more acceptable for stigmatized topics, but still entail considerable barriers that deter the most vulnerable. Conclusions: Delivery and evaluation of brief evidence-based interventions from a UCHS could lead to improved maternal and child health outcomes through a more responsive and equitable service. We recommend three interventions that meet our criteria of “best bet” interventions.
Migrants’ and refugees’ health status and healthcare in Europe: A scoping literature review
Authors: Lebano Adele , Hamed Sarah , Bradby Hannah , Gil-Salmerón Alejandro , Durá-Ferrandis Estella , Garcés-Ferrer Jorge , Azzedine Fabienne , Riza Elena , Karnaki Pania , Zota Dina , Linos Athena 
Published: May 2020

Abstract
Background There is increasing attention paid to the arrival of migrants from outwith the EU region to the European countries. Healthcare that is universally and equably accessible needs to be provided for these migrants throughout the range of national contexts and in response to complex and evolving individual needs. It is important to look at the evidence available on provision and access to healthcare for migrants to identify barriers to accessing healthcare and better plan necessary changes. Methods This review scoped seventy seven papers from nine European countries (Austria, Cyprus, France, Germany, Greece, Italy, Malta, Spain, and Sweden) in English and in country-specific languages in order to provide an overview of migrants’ access to healthcare. The review aims at identifying what is known about access to healthcare and healthcare use of migrants and refugees in the EU member states. The evidence included documents from 2011 onward. Results The literature reviewed confirms that despite the aspiration to ensure equality of access to healthcare, there is persistent inequalities between migrants and non-migrants in access to healthcare services. The evidence shows unmet healthcare needs, especially when it comes to mental and dental health as well as the existence of legal barriers in accessing healthcare. Language and communication barriers, overuse of emergency services and underuse of primary healthcare services as well as discrimination are described. Conclusions The European situation concerning migrants’ and refugees’ health status and access to healthcare is heterogenous and it is difficult to compare and draw any firm conclusions due to the scant evidence. Different diseases are prioritised by different countries, although these priorities do not always correspond to the expressed needs or priorities of the migrants. Mental healthcare, preventive care (immunization) and long term care in the presence of a growing migrant older population are identified as priorities that deserve greater attention. There is a need to improve the existing data on migrants’ health status, needs and access to healthcare to be able to tailor care to the needs of migrants. To conduct research that highlights migrants’ own views on their health and barriers to access to healthcare is key.
Raman and FT-IR Spectroscopy investigation the cellulose structural differences from bacteria Gluconacetobacter sucrofermentans during the different regimes of cultivation on a molasses media
Authors: Atykyan Nelli , Revin Victor , Shutova Vitalina 
Published: May 2020

Abstract
Raman and Fourier Transform Infrared (FT-IR) spectroscopy was used for investigation of structural differences of bacterial celluloses (BC), obtained by cultivation native and immobilized cells of Gluconacetobacter sucrofermentans during static and dynamic regimes of cultivation on a molasses media. It was found that the Raman and FT-IR spectra could characterized the groups of the cellulose molecules. The culturing bacterial cellulose in the presence of results in an increase of crystalline and it increased during cultivated on a molasses media with the addition of 1.5% ethanol - 75.62%. The degree of BC crystallinity increased during dynamic regime of cultivation is higher than under static regime one. The maximal BC content was observed when 0.5% ascorbic acid was added to the cultivation medium with molasses and native cells. It was found, the degree of BC crystallinity during static regime cultivation on a molasses medium with ethanol, increased significantly to 73.5%, and during dynamic regime - 75.6%. So, in this study, the changes of the bacterial cellulose conformation of were revealed during bacterial cultivation in a medium containing molasses in various cultivation modes.
Identification of the molecular mechanism and diagnostic biomarkers in the thoracic ossification of the ligamentum flavum using metabolomics and transcriptomics
Authors: Li Jiahao , Yu Lingjia , Guo Shigong , Zhao Yu 
Published: May 2020

Abstract
Background: To establish a metabolite fingerprint of ossification of the thoracic ligamentum flavum (OTLF) patients using liquid chromatography-mass spectrometry (LC-MS) in combination with transcriptomic data and explore the potential molecular mechanism of pathogenesis.Results: The study cohort was composed of 25 patients with OTLF and 23 healthy volunteers as a control group. 37 metabolites were identified out by UPLC-MS including uric acid and hypoxanthine. 9 metabolites, including uric acid and hypoxanthine, were found with a Variable Importance in Projection (VIP) score over 1 (p<0.05). Pathway enrichment indicated that purine metabolism pathways and the other four metabolism pathways were enriched. Transcriptomic data revealed that purine metabolism have a substantial change in gene expression of OTLF and that xanthine dehydrogenase (XDH) is the key regulatory factor. Receiver operating characteristic (ROC) analysis indicated that 17 metabolites, including uric acid, were found with an AUC value of over 0.7. Conclusion: Uric acid might be the potential biomarker for OTLF and play an important role within the detailed pathway. XDH could affect purine metabolism by suppressing the expression of hypoxanthine and xanthine leading to low serum levels of uric acid in OTLF, which could be a focal point in developing new therapeutic methods for OTLF.
High uptake of 68Ga-PSMA and 18F-DCFPyL in the peritumoral area of rat gliomas due to activated astrocytes
Authors: Oliveira Dennis , Stegmayr Carina , Heinzel Alexander , Ermert Johannes , Neumaier Bernd , Shah Nadim Jon , Mottaghy Felix M. , Langen Karl-Josef , Willuweit Antje 
Published: May 2020

Abstract
Background Recent studies reported on high uptake of the PSMA ligands [ 68 Ga]HBED-CC ( 68 Ga-PSMA) and 18 F-DCFPyL in cerebral gliomas. This study explores the regional uptake and cellular targets of 68 Ga-PSMA and 18 F-DCFPyL in three different rat glioma models. Methods F98, 9L or U87 rat gliomas were implanted into the brains of 38 rats. After 13 days of tumor growth, 68 Ga-PSMA (n=21) or 18 F-DCFPyL (n=17) were injected intravenously and animals were sacrificed 40 min later. Five animals for each tracer and tumor model were additionally investigated by micro-PET at 20-40 min postinjection. Cryosections of the tumor bearing brains were analyzed by ex vivo autoradiography and immunofluorescence staining for blood vessels, microglia, astrocytes and presence of PSMA. Blood-brain barrier (BBB) permeability was tested by coinjection of Evans blue dye (EBD). 68 Ga-PSMA uptake after restoration of BBB integrity by treatment with dexamethasone (Dex) was evaluated in four animals with U87 gliomas. Competition experiments using the PSMA-receptor inhibitor 2-(Phosphonomethyl)pentane-1,5-dioic acid (PMPA) were performed for both tracers in two animals each. Results Autoradiography demonstrated a strong 68 Ga-PSMA and 18 F-DCFPyL binding in the peritumoral area and moderate binding in the center of the tumors. PMPA administration led to complete inhibition of 68 Ga-PSMA and 18 F-DCFPyL binding in the peritumoral region. Restoration of BBB by Dex treatment reduced EBD extravasation but 68 Ga-PSMA binding remained unchanged. Expression of activated microglia (CD11b) was low in the intra- and peritumoral area but GFAP staining revealed strong activation of astrocytes in congruency to the tracer binding in the peritumoral area. All tumors were visualized in micro PET, showing a lower tumor/brain contrast with 68 Ga-PSMA than with 18 F-DCFPyL. Conclusions High uptake of 68 Ga-PSMA and 18 F-DCFPyL in the peritumoral area of all glioma models is presumably caused by activated astrocytes. This may represent a limitation for the clinical application of PSMA ligands in gliomas.
Comparative Analysis of The Two Sites of Lahe (Caulerpa sp.) Growth for Determine The Range of Atmospheric, Physical and Chemical Water Conditions
Authors: Medellu Christophil , Suriani Ni Wayan , Komansilan Alfrits 
Published: May 2020

Abstract
Background

Ecological conditions determine the growth and productivity of lahe (Caulerpa Sp.). We conduct a comparative study of ecological conditions that affected differences in growth and productivity of lahe in two locations, in the Batunderang village area and the Lapango village area, Sangihe Regency. The ecological factors that we examined include atmospheric, chemical and physical factors. Atmospheric variables include radiation intensity, duration of irradiation, the air temperature above sea level. The physical and chemical parameters of water studied include current velocity, seawater temperature, salinity, current strength, pH, dissolved oxygen, and nitrate concentrations.
Results

The indicator of lahe growth are: chain length, stem diameter, meristem diameter. The productivity indicator is the wet weight of the lahe harvested by farmers within 90 days. Comparative analysis between locations and measurement positions summarizes the range of ecological conditions for natural growth. The seabed for lahe is 0.8 m − 1.4 m lower than the surface of a coral reef and is not exposed at the lowest tide. The air temperature range at position 20 cm above sea level is 250C − 31.60C, while the temperature of seawater varies between 250C to 28.40C. Daily fluctuations in current velocity at high tides range from 0.09 cm/sec to 2 cm/sec. The salinity range between 27.8 ppt to 28.6 ppt. The pH range of seawater for natural growth is 7.6–8.12, while the dissolved oxygen range is 6 ppm to 6.25 ppm. Nitrate concentrations in lahe growth positions vary between 1.8 ppm − 1.96 ppm.
Conclusion

This ecological condition guarantees that the productivity of lahe varies between 20–30 kg/m2 for a 90-day harvest period.
Performance comparison approach of different disease prediction studies using quantitative index
Authors: ElHamdaoui Halima , Boujraf Said 
Published: May 2020

Abstract
Background and aim Comparing databases performances is quite challenging, especially they are presenting different characteristics including the quantitative and quantitative aspects acquired. The primary aim of this paper is to introduce a quantitative method for performance comparison of prediction of diseases studies using measurable parameters. Results The proposed method focuses on the following parameters: the accuracy and the number of attributes, to compute the performance index. We outline the major obstacles in terms of the construction of a comparative reliable approach, and a demonstrative case regarding the prediction of heart disease is given to validate the effectiveness of the proposed method. Conclusions Comparing performance of databases used in computer aided diagnosis should be based on objective quantitative basis, inhere presented index allows to achieve this goal, and overcome the variability found through databases. The presented methods should constitute a major tool for normalizing the comparison of databases performances, hence allowing more transparent and better evidencing databases qualities.
Work-related factors affecting the retention of medical officers in the preventive healthcare sector of Sri Lanka
Authors: Arnold Mahendra , Fernando Dinusha , Wickramanayake Kapila , Karunapema Palitha , Wickramatilake Sepali , Fernando Yamuna , Denawaka Chandani , Mahesh Pasyodun Koralage Buddhika , Panditharathna Sujeewa 
Published: May 2020

Abstract
Background: Human resources are the livelihood of all types of organizations. The biggest challenge that organizations are facing today is not only managing these resources but also retaining them. Preventive health sector plays a vital role in the healthcare system. Medical Officers of Health (MOH) are the Medical Officers providing preventive health services in Sri Lanka. This study was carried out to explore the factors affecting retention of Medical Officers of Health in the preventive health sector in Sri Lanka.Methods: A descriptive cross sectional study was carried out among Medical Officers of Health in the Colombo district which has 18 MOH Offices with 64 Medical Officers. A pre-tested self-administered questionnaire was used as the study instrument. Data were analyzed using descriptive analysis, correlation and regression analysis. Results: Regression analysis showed that all four variables; recognition, work schedule, remuneration and responsibility are positively and significantly correlated with retention of Medical Officers of Health in the preventive health sector. The variable ‘work schedule’ showed the highest impact to the retention of Medical Officers of Health.Conclusions: In order to retain trained Medical Officers of Health in the Sri Lankan preventive health sector, health authorities should address the factors that influence retention. If policy makers fail to address these factors the preventive health services will be negative impact due to shortage of key service providers.