bluuebunny/crossref_metadata_2025_split huggingface dataset:
Overcoming bacterial resistance to antibiotics: the urgent need – a review
Authors: Stachelek Magdalena , Zalewska Magdalena , Kawecka-Grochocka Ewelina , Sakowski Tomasz , Bagnicka Emilia 
Published: November 2020

Abstract
The discovery of antibiotics is considered one of the most crucial breakthroughs in medicine and veterinary science in the 20th century. From the very beginning, this type of drug was used as a ‘miraculous cure’ for every type of infection. In addition to their therapeutic uses, antibiotics were also used for disease prevention and growth promotion in livestock. Though this application was banned in the European Union in 2006, antibiotics are still used in this way in countries all over the world. The unlimited and unregulated use of antibiotics has increased the speed of antibiotic resistance’s spread in different types of organisms. This phenomenon requires searching for new strategies to deal with hard-to-treat infections. The antimicrobial activity of some plant derivatives and animal products has been known since ancient times. At the beginning of this century, even more substances, such as antimicrobial peptides, were considered very promising candidates for becoming new alternatives to commonly used antimicrobials. However, many preclinical and clinical trials ended without positive results. A variety of strategies to fight microbes exist, but we are a long way from approving them as therapies. This review begins with the discovery of antibiotics, covers the modes of action of select antimicrobials, and ends with a literature review of the newest potential alternative approaches to overcoming the drug resistance phenomenon.
Effects of Melatonin on Cadmium Accumulation and Haematological Parameters in Cadmium Intoxicated Prussian Carp (Carassius gibelio B.)
Authors: Drąg-Kozak Ewa , Łuszczek-Trojnar Ewa , Socha Magdalena , Bojarski Bartosz 
Published: November 2020

Abstract
The present study was performed to determine the effect of melatonin on cadmium accumulation and haematological parameters changes in females of Prussian carp (Carassius gibelio B.). The fish were exposed to a sublethal concentration of cadmium (0.4 and 4.0 mg/L) without or with melatonin implant (containing 18 mg melatonin hormone) for 1, 4, 7, 10 and 13 weeks. After the 7th week, Cd-exposed fish were divided into two groups. The first group of fish were subjected to depuration in clear water, while the second group remained exposed to the same concentrations of cadmium. After the 10th and 13th weeks of exposure the kidney, spleen, heart and blood were taken in order to determine the cadmium concentration and to analyse haematological parameters. The results of this study showed an increase in the concentration of cadmium in the tissues and blood in fish exposed to the highest dose (4.0 mg/L) of cadmium in water with a dependence on the exposure duration. Additionally, it was shown that melatonin administration reduced the cadmium concentration in the tissues and blood, and melatonin had a protective effect against cadmium accumulation. Moreover, the results showed a significant increase in blood parameters (RBC, Ht and Hb) in fish treated with the highest dose of cadmium. However, implantation of melatonin in cadmium-treated fish resulted in marked improvements in haematological parameters. Thus, melatonin can be a good implementation to alleviate, at least partially, the toxicity of cadmium.
Route selection, migration speed, and mortality of silver eel passing through two small hydroelectric facilities
Authors: Dębowski Piotr , Bernaś Rafał , Skóra Michał , Morzuch Jacek 
Published: November 2020

Abstract
The European eel is a highly threatened species according the European Inland Fisheries Advisory Commission (EIFAC) and the Food and Agriculture Organization of the United Nations (FAO). The recruitment of this species has collapsed over the last fifty years primarily because of the destruction of free migration routes and overfishing. One of the most important factors linked to population decline is mortality during catadromous migration caused by hydroelectric facilities. The aim of the present study was to assess the mortality rate of silvers eel passing through two small hydroelectric facilities. Total mortality at the site was 5%, but it was 15% for fish passing through the two hydroelectric facilities. However, the cumulative mortality in the river basin studied, which has many hydroelectric facilities, indicated that silver eel escapement from the Słupia drainage basin was very low.
Histoanatomy and surface ultrastructure of the olfactory organ of the freshwater tank goby, Glossogobius giuris (Hamilton, 1822)
Authors: Ghosh Saroj Kumar 
Published: November 2020

Abstract
Characteristic features of histology and fine morphology of the olfactory organ in the tank goby, Glossogobius giuris (Perciformes, Gobiidae, Gobiinae), were investigated with light and scanning electron microscopy. The olfactory cavity contained single lamellae that were exposed to the aquatic environment by small anterior and posterior nostrils. Typical olfactory rosettes were not observed. Histologically, each lamella consisted of two layers of epithelium; wrapping the central core that was composed of connective tissue stroma with nerve fibers and blood capillaries. The mucosal lining of lamella was merged with sensory and non-sensory olfactory cells, identified on the basis of structural characters, surface specializations, and staining features. The principal sensory elements were ciliated receptor cells that were characterized by apical dendritic processes expanded from cell soma and microvillous receptor cells equipped with multiple tiny dendrons on the mucosal surface. The bead-like appearance of several labyrinth cells, mucous cells with secreted mucin, scattered lymphatic cells, stratified epithelial cells bearing microfolds, and condensed ciliated supporting cells were observed in the non-sensory epithelia. Undifferentiated basal cells were embedded in the deeper zone of the epithelium above the basement membrane. The cellular organization of the olfactory lining was interpreted with chemoreception of the fish concerned.
Feeding habits of oriental sole (Brachirus orientalis) on the Bushehr coast of the Persian Gulf
Authors: Alghada Dima , Keivany Yazdan , Paykan-Heyrati Fatemeh 
Published: November 2020

Abstract
The feeding habits of oriental sole, Brachirus orientalis (Bloch & Schneider) were investigated using 300 male and female specimens collected from coastal waters of Bushehr Province (Persian Gulf) between June 2015 and July 2016. The total length of females and males ranged from 16.2 to 38.5 cm and 14.1 to 29.1 cm, respectively. Of the total number of stomachs examined, 225 were empty (vacuity index = 77%). This index varied significantly over the year (P < 0.05), with maximum values in April and September and minimum in October and May. The B. orientalis diet was composed of nine prey species belonging to five classes. The most important prey items were Crustacea and Mollusca (Bivalvia and Gastropoda). Diet composition showed little seasonal variation, and Crustacea, Bivalvia, and Gastropoda were the most important prey items in all seasons. Sex did not appear to have any significant effects on dietary composition, and the main prey items were consumed by both males and females (P > 0.05).
Successful Extensive Multiorgan Resection of Malignant Duodenal Tumor: A Case Report
Authors: Spiridonova Ilva , Sīviņš Armands 
Published: November 2020

Summary
Duodenal adenocarcinoma is one of the rarest tumours of all gastrointestinal malignancies. Due to rarity and late symptoms, duodenal cancers are diagnosed in late stage, but overall survival rate is high. We present a case of locally advanced duodenal adenocarcinoma with successful surgical treatment including multiorgan resection.
Thrips (Thysanoptera) associated with onion (Allium cepa L.) and Welsh onion (Allium fistulosum L.)
Authors: Olczyk Marta , Pobożniak Maria 
Published: November 2020

Abstract
We determined the abundance, species composition, sex ratio and seasonal dynamics of thrips on one cultivar of Welsh onion (Allium fistulosum) and eight cultivars of onion (Allium cepa) in South Poland within three vegetation seasons (2014–2016). Nine species of Thysanoptera were identified on A. cepa and A. fistulosum. Irrespective of the onion cultivar, Thrips tabaci was the dominant species (64.4% of all collected thrips specimens), while Frankliniella intonsa also occurred in high numbers (28.3%). Conversely, Welsh onion was most often inhabited by F. intonsa (62.7%), although T. tabaci was also numerous (28.3%). The predatory Aeolothrips intermedius accounted for 4.5% on A. cepa and 2.9% on A. fistulosum. In the most numerous species, T. tabaci, F. intonsa and A. intermedius populations were formed mainly by females. The cultivar most colonised by thrips was Kroll of A. fistulosum. The tested cultivars of A. cepa demonstrated varying degrees of attractiveness to thrips in the subsequent years. The relationship between populations of T. tabaci, F. intonsa and A. intermedius changed in the subsequent months of the growing season. In June, mainly T. tabaci and F. intonsa occurred on onion plants, while from July, the percentage shares of F. intonsa and the predatory A. intermedius in the thrips population on many onion cultivars increased. The level of attractiveness of A. cepa related to onion thrips, which is reported as a main pest of onion, varies depending on the year and cultivar.
Efficacy of Miltefosine and Artemether on infected Biomphalaria alexandrina snails with Schistosoma mansoni: immunological and histological studies
Authors: Abdel-Azeem H. H. , Osman G. Y. , El Garhy M. F. , Al Benasy K. S. 
Published: November 2020

Summary

Biomphalaria alexandrina snails have received much attention due to their great medical importance as vectors for transmitting Schistosoma mansoni infection to humans. The main objective of the present work was to assess the efficacy of miltefosin a synthetic molluscicidal drug and artemether a natural molluscicidal drug. The correlation between immunological and histological observations from light and electron microscopy of the hemocytes of B. alexandrina post treatment with both drugs was also evaluated. LC50 and LC90 values were represented by 13.80 ppm and 24.40 ppm for miltefosine and 16.88 ppm and 27.97 ppm for artemether, respectively. The results showed that the treatment of S. mansoni-infected snails and normal snails with sublethal dose of miltefosine (LC25=8.20 ppm) and artemether (LC25=11.04 ppm) induced morphological abnormalities and a significant reduction in hemocytes count.
Experimental infection with Baylisascaris potosis in chickens
Authors: Taira K. , Ueda M. , Ooi H. K. 
Published: November 2020

Summary
The larvae of the genus Baylisascaris can cause larva migrans in mammals and birds. This study investigated the larval migration of Baylisascaris potosis, the roundworm of kinkajou (Potos flavus), in chickens and the associated clinical manifestations of the host. Thirty-six 3-week-old chickens divided into 6 groups were orally inoculated with 3,000 B. potosis eggs/chick. Each group of chicken was necropsied at days 1, 2, 3, 7, 30 and 90 PI (post inoculation), and the number of larvae in various organs were counted until day 90 PI. No clinical signs were observed in chickens during the study. Larvae were detected from the liver, lungs or breast-muscles of 13/36 (36.1%) chickens. The mean total number of larvae in the liver, lungs and breast-muscles at days 1, 2, 3, 7, 30 and 90 PI were 0.34, 0.17, 1.66, 1.01, 0.17 and 0, respectively. No larvae were found in the brain, eyes, hid-limb muscles, heart, kidneys and spleen. Although infectivity of larvae in egg-inoculated chickens was low, the present study demonstrated that B. potosis larvae can migrate in chickens tissues up to day 30 PI. The result suggests that chickens can serve as a paratenic host for B. potosis and may underline a public health importance of B. potosis infection as a potential foodborne disease in humans.
The Association between Researchers’ Conceptions of Research and Their Strategic Research Agendas
Authors: Santos João M. , Horta Hugo 
Published: November 2020

Abstract

Purpose
In studies of the research process, the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked. This study aims to address this gap.

Design/methodology/approach
This study analyzes this relationship using a dataset of more than 8,500 researchers across all scientific fields and the globe. It studies the associations between the dimensions of two inventories: the Conceptions of Research Inventory (CoRI) and the Multi-Dimensional Research Agenda Inventory—Revised (MDRAI-R).

Findings
The findings show a relatively strong association between researchers’ conceptions of research and their research agendas. While all conceptions of research are positively related to scientific ambition, the findings are mixed regarding how the dimensions of the two inventories relate to one another, which is significant for those seeking to understand the knowledge production process better.

Research limitations
The study relies on self-reported data, which always carries a risk of response bias.

Practical implications
The findings provide a greater understanding of the inner workings of knowledge processes and indicate that the two inventories, whether used individually or in combination, may provide complementary analytical perspectives to research performance indicators. They may thus offer important insights for managers of research environments regarding how to assess the research culture, beliefs, and conceptualizations of individual researchers and research teams when designing strategies to promote specific institutional research focuses and strategies.

Originality/value
To the best of the authors’ knowledge, this is the first study to associate research agendas and conceptions of research. It is based on a large sample of researchers working worldwide and in all fields of knowledge, which ensures that the findings have a reasonable degree of generalizability to the global population of researchers.
Changes in the Secondary Landscape Structure in Hruby Jesenik Mountains (Czech Republic)
Authors: Dostal Adam , Machar Ivo , Mackovcin Peter 
Published: November 2020

Abstract
This study deals with the analysis of changes in the secondary landscape structure of the territory of the Jeseniky Mountains (Czech Republic) monitored in the years 1946, 1953, 1962, 2000, and 2016. The study analysed georeferencing aerial geodetic images in the QGIS 2.18 program. On the basis of the land use classification key that was created, historical changes were identified in the following categories of land use; forest, arable land, orchards, water surfaces, wild life refuges and scattered greenery, river networks, permanent grass stands, meadows and pastures, gardens and built-up areas, courtyards and hard surfaces. The surface areas of land use categories were utilized for the calculation of change indicators regarding the structure of the landscape (landscape similarity index, coefficient of ecological stability, and change index). The maps for land use created for individual historical periods functioned as the starting point for a comprehensive assessment of the landscape by means of a SWOT analysis, which created the basis for a proposal for permanently sustainable utilization of the landscape in the area that was monitored. The study results indicate that the analysis of the historical development of the secondary landscape structure may be utilized as a decision support tool when planning sustainable landscape management.
Examining Organic Acid Root Exudate Content and Function for Leafy Vegetables Under Water-Stressed Conditions
Authors: Kasukawa Naho , Miyazawa Kae 
Published: November 2020

Abstract
At the plants’ exposal to abiotic stress, organic acids, including citric acid, are exuded through their roots. Previous studies have suggested that the exogenous application of citric acid increases antioxidant activity within the plant. Thus, we postulated that organic acids released into the surroundings during times of environmental stress may function as signaling molecules to increase antioxidant enzyme activity. To gain further insight into this phenomenon, we identified individual organic acids exuded from the roots of leafy vegetables under drought stress. We then analyzed enzyme activity and the root/shoot lengths of seedlings after treatment with the types of organic acids found to be exuded from the studied leafy vegetables, including acetic, citric, lactic, and tartaric acids. There was a significant increase in catalase and ascorbate peroxidase enzyme activity in Napa cabbage (Brassica rapa var. pekinensis) after exogenous citric acid application. Root lengths of cabbage (Brassica oleracea var. capitata) and Napa cabbage seedlings were significantly longer in citric and lactic acids pretreated seedlings compared to those of the control. The above results support the conclusion that exogenous application of citric acid alleviates drought stress. However, there is insufficient evidence to prove that organic acids act as signaling molecules to prime neighboring plants for upcoming stress.
The Impact of the State of Emergency on the Supply of Services and Passenger Demand for Public Transport
Authors: Konečný Vladimír , Brídziková Mária 
Published: November 2020

Abstract
The paper deals with the research of the demand and supply of public passenger transport services in the state of emergency caused by the COVID-19 disease. The extraordinary situation has been affecting the behaviour and decision-making of passengers and their demand for public transport not only in the Slovak Republic but globally. The situation has caused a significant decline in passenger transport as well as changes in the structure of passengers who still use the public transport system. Several operators have responded to declining demand by reducing the transport services supply, to reduce operating costs. The declining demand is reflected in a decrease in transport revenues and an increase in the demonstrable loss of operators providing public passenger transport services.
Subsolidus solution and ionic conductivity of rock-salt structured Li3+5xTa1−xO4 electroceramics
Authors: Shari S. , Tan K.B. , Khaw C.C. , Zainal Z. , Lee O.J. , Chen S.K. 
Published: November 2020

Abstract
Lithium tantalate solid solution, Li3+5xTa1−xO4 was prepared by conventional solid-state reaction at 925 °C for 48 h. The XRD analysis confirmed that these materials crystallized in a monoclinic symmetry, space group C2/C and Z = 8, which was similar to the reported International Crystal Database (ICDD), No. 98-006-7675. The host structure, β-Li3TaO4 had a rock-salt structure with a cationic order of Li+:Ta5+ = 3:1 over the octahedral sites. A rather narrow subsolidus solution range, i.e. Li3+5xTa1−xO4 (0 ⩽ x ⩽ 0.059) was determined and the formation mechanism was proposed as a replacement of Ta5+ by excessive Li+, i.e. Ta5+ ↔ 5Li+. Both Scherrer and Williamson-Hall (W-H) methods indicated the average crystallite sizes in the range of 31 nm to 51 nm. Two secondary phases, Li4TaO4:5 and LiTaO3 were observed at x = 0.070 and x = −0:013, respectively. These materials were moderate lithium ionic conductors with the highest conductivity of ~2.5 × 10−3 Ω −1 ˙ cm−1 at x = 0, at 0 °C and 850 °C; the activation energies were found in the range of 0.63 eV to 0.68 eV.
Comparison of electrical properties of CuO/n-Si contacts with Cu/n-Si
Authors: Özmenteş Reşit , Temirci Cabir 
Published: November 2020

Abstract
In this study, CuO/n-Si/Al heterojunction contacts were fabricated by thermal evaporation technique. Electrical characteristics of the samples were investigated with the current-voltage (I-V), capacitance-voltage/frequency (C-V/f), and conductancevoltage (G/V) measurements at room temperature. Also, Cu/n-Si/Al Schottky contact was produced as a reference sample to investigate the electrical properties of the samples. The values of ideality factor (n), barrier height ( Φb) and series resistance (Rs) of the samples were calculated from the forward bias current-voltage (I-V) and reverse bias capacitance-voltage (C-V) characteristics. Also, for checking the consistency of the results, Cheung and Norde functions were used. The experimental result values of CuO/n-Si contact were compared with the values of the reference Cu/n-Si Schottky diode. It was observed that the values of the ideality factor and barrier height of the CuO/n-Si heterojunction were higher than those of the Cu/n-Si Schottky contact, while the series resistance was lower. Also, it has been observed that the value of capacitance decreased with increasing frequency and after a certain value of frequency it was almost constant. The ideality factor of CuO/n-Si/Al heterostructure is about 2.40 and so, it is not close to the ideal behavior.
Migrant and Non-Migrant Origin Pre-Service Teachers’ Beliefs about Multilingualism and Teaching in Multilingual Classrooms: Convergences and Divergences
Authors: Llompart Júlia , Birello Marilisa 
Published: November 2020

Summary
This article reports findings from an investigation into migrant and non-migrant origin pre-service teachers’ beliefs about multilingualism and the relationship between their linguistic trajectories as students and how they perceive themselves as future teachers. We analize the beliefs of around seventy pre-service teachers taking part in a university course, collected through an individual reflection tool based on a SWOT analysis (Strengths, Weaknesses, Opportunities, Threats) and a group discussion in which students had to discuss their ideas and create a collective document. In this article we focus on the discourse of four pre-service teachers, two of whom had migration backgrounds and two of whom who did not. Findings suggest that pre-service teachers’ life and learning experiences contribute to different emotions and feeling about language and teaching in a multilingual setting. They also influence the perception the pre-service teachers have of themselves as future teachers. Pre-service teachers regard the preparation received at the university negatively and express insecurities. Findings illustrate that migrant origin pre-service teachers feel more prepared in the sense they believe that their migration experience can help to understand newcoming students and be empathic with them.