bluuebunny/crossref_metadata_2025_split huggingface dataset:
Highway to (Digital) Surveillance: When Are Clients Coerced to Share Their Data with Insurers?
Authors: Loi Michele , Hauser Christian , Christen Markus 
Published: November 2020

AbstractClients may feel trapped into sharing their private digital data with insurance companies to get a desired insurance product or premium. However, private insurance must collect some data to offer products and premiums appropriate to the client’s level of risk. This situation creates tension between the value of privacy and common insurance business practice. We argue for three main claims: first, coercion to share private data with insurers is pro tanto wrong because it violates the autonomous choice of a privacy-valuing client. Second, we maintain that irrespective of being coerced, the choice of accepting digital surveillance by insurers makes it harder for the client to protect his or her autonomy (and to act spontaneously and authentically). The violation of autonomy also makes coercing customers into digital surveillance pro tanto morally wrong. Third, having identified an economically plausible process involving no direct coercion by insurers, leading to the adoption of digital surveillance, we argue that such an outcome generates further threats against autonomy. This threat provides individuals with a pro tanto reason to prevent this process. We highlight the freedom dilemma faced by regulators who aim to prevent this outcome by constraining market freedoms and argue for the need for further moral and empirical research on this question.
Effectiveness of diet and physical activity interventions amongst adults attending colorectal and breast cancer screening: a systematic review and meta-analysis
Authors: Orange Samuel T. , Hicks Kirsty M. , Saxton John M. 
Published: November 2020

Abstract
Purpose
To estimate the effectiveness of tailored physical activity and dietary interventions amongst adults attending colorectal and breast cancer screening.

Methods
Five literature databases were systematically searched to identify randomised controlled trials (RCTs) of tailored physical activity and/or dietary interventions with follow-up support initiated through colorectal and breast cancer screening programmes. Outcomes included markers of body fatness, physical activity, and dietary intake. Mean differences (MDs) or standardised mean differences (SMDs) with 95% confidence intervals (CIs) were pooled using random effects models.

Results
Five RCTs met the inclusion criteria encompassing a total of 722 participants. Diet and physical activity interventions led to statistically significant reductions in body mass (MD − 1.6 kg, 95% CI − 2.7 to − 0.39 kg; I2 = 81%; low quality evidence), body mass index (MD − 0.78 kg/m2, 95% CI − 1.1 to − 0.50 kg/m2; I2 = 21%; moderate quality evidence), and waist circumference (MD − 2.9 cm, 95% CI − 3.8 to − 1.91; I2 = 0%; moderate quality evidence), accompanied by an increase in physical activity (SMD 0.31, 95% CI 0.13 to 0.50; I2 = 0%; low quality evidence) and fruit and vegetable intake (SMD 0.33, 95% CI 0.01 to 0.64; I2 = 51%; low quality evidence).

Conclusion
There is low quality evidence that lifestyle interventions involving follow-up support lead to modest weight loss and increased physical activity and fruit and vegetable intake. Due to the modest intervention effects, low quality of evidence and small number of studies, further rigorously designed RCTs with long-term follow-up of modifiable risk factors and embedded cost–benefit analyses are warranted (PROSPERO ref: CRD42020179960).
Cyclin-dependent kinase inhibitors in head and neck cancer and glioblastoma—backbone or add-on in immune-oncology?
Authors: Riess Christin , Irmscher Nina , Salewski Inken , Strüder Daniel , Classen Carl-Friedrich , Große-Thie Christina , Junghanss Christian , Maletzki Claudia 
Published: November 2020

AbstractCyclin-dependent kinases (CDK) control the cell cycle and play a crucial role in oncogenesis. Pharmacologic inhibition of CDK has contributed to the recent clinical approval of dual CDK4/6 inhibitors for the treatment of breast and small cell lung cancer. While the anticancer cell effects of CDK inhibitors are well-established, preclinical and early clinical studies describe additional mechanisms of action such as chemo- and radiosensitization or immune stimulation. The latter offers great potential to incorporate CDK inhibitors in immune-based treatments. However, dosing schedules and accurate timing of each combination partner need to be respected to prevent immune escape and resistance. In this review, we provide a detailed summary of CDK inhibitors in the two solid cancer types head and neck cancer and glioblastoma multiforme; it describes the molecular mechanisms of responsevs.resistance and covers strategies to avoid resistance by the combination of immunotherapy or targeted therapy.
Task Sharing or Task Dumping: Counsellors Experiences of Delivering a Psychosocial Intervention for Mental Health Problems in South Africa
Authors: Jacobs Y. , Myers B. , van der Westhuizen C. , Brooke-Sumner C. , Sorsdahl K. 
Published: November 2020

AbstractGiven task-sharing mental health counselling to non-specialist providers is a recognised strategy to increase service capacity, ensuring that their training, supervision, and support needs are met is necessary to facilitate the sustainable delivery of a high-quality service. Using in-depth interviews, we qualitatively explored the experiences of 18 facility-based counsellors (FBCs) tasked with delivering a counselling intervention within chronic disease services offered within primary care facilities participating in the project MIND cluster randomised controlled trial. Findings show that project MIND training with a strong emphasis on role playing and skills rehearsal improved FBCs’ confidence and competence, complemented by highly structured supervision and debriefing provided by a registered counsellor, were key strategies for supporting the implementation of task-shared mental health counselling. FBCs perceived many benefits to providing mental health counselling in primary healthcare but systemic interventions are needed for sustained implementation.
Representing Attitudes Towards Ambiguity in Hilbert Space: Foundations and Applications
Authors: Sozzo Sandro 
Published: November 2020

AbstractWe provide here a general mathematical framework to model attitudes towards ambiguity which uses the formalism of quantum theory as a “purely mathematical formalism, detached from any physical interpretation”. We show that the quantum-theoretic framework enables modelling of the Ellsberg paradox, but it also successfully applies to more concrete human decision-making tests involving financial, managerial and medical decisions. In particular, we elaborate a mathematical representation of various empirical studies which reveal that attitudes of managers towards uncertainty shift from ambiguity seeking to ambiguity aversion, and viceversa, thus exhibiting hope effects and fear effects. The present framework provides a promising direction towards the development of a unified theory of decisions in the presence of uncertainty.
Decades needed for ecosystem components to respond to a sharp and drastic phosphorus load reduction
Authors: Chorus Ingrid , Köhler Antje , Beulker Camilla , Fastner Jutta , van de Weyer Klaus , Hegewald Tilo , Hupfer Michael 
Published: November 2020

AbstractLake Tegel is an extreme case of restoration: inflow treatment reduced its main external phosphorus (TP) load 40-fold, sharply focused in time, and low-P water flushed the lake volume ≈ 4 times per year. We analysed 35 years of data for the time TP concentrations took to decline from ≈ 700 to 20–30 µg/l, biota to respond and cyanobacteria to become negligible. The internal load proved of minor relevance. After 10 years, TP reached 35–40 µg/l, phytoplankton biomass abruptly declined by 50% and cyanobacteria no longer dominated; yet 10 years later at TP < 20–30 µg/l they were below quantifiable levels. 20–25 years after load reduction, the lake was stably mesotrophic, macrophytes had returned down to 6–8 m, and vivianite now forms, binding P insolubly in the sediment. Bottom-up control of phytoplankton through TP proved decisive. Five intermittent years with a higher external P load caused some ‘re-eutrophication’, delaying recovery by 5 years. While some restoration responses required undercutting thresholds, particularly that of phytoplankton biomass to TP, resilience and hysteresis proved irrelevant. Future research needs to focus on the littoral zone, and for predicting time spans for recovery more generally, meta-analyses should address P load reduction in combination with flushing rates.
Blind MV-based video steganalysis based on joint inter-frame and intra-frame statistics
Authors: Ghamsarian Negin , Schoeffmann Klaus , Khademi Morteza 
Published: November 2020

AbstractDespite all its irrefutable benefits, the development of steganography methods has sparked ever-increasing concerns over steganography abuse in recent decades. To prevent the inimical usage of steganography, steganalysis approaches have been introduced. Since motion vector manipulation leads to random and indirect changes in the statistics of videos, MV-based video steganography has been the center of attention in recent years. In this paper, we propose a 54-dimentional feature set exploiting spatio-temporal features of motion vectors to blindly detect MV-based stego videos. The idea behind the proposed features originates from two facts. First, there are strong dependencies among neighboring MVs due to utilizing rate-distortion optimization techniques and belonging to the same rigid object or static background. Accordingly, MV manipulation can leave important clues on the differences between each MV and the MVs belonging to the neighboring blocks. Second, a majority of MVs in original videos are locally optimal after decoding concerning the Lagrangian multiplier, notwithstanding the information loss during compression. Motion vector alteration during information embedding can affect these statistics that can be utilized for steganalysis. Experimental results have shown that our features’ performance far exceeds that of state-of-the-art steganalysis methods. This outstanding performance lies in the utilization of complementary spatio-temporal statistics affected by MV manipulation as well as feature dimensionality reduction applied to prevent overfitting. Moreover, unlike other existing MV-based steganalysis methods, our proposed features can be adjusted to various settings of the state-of-the-art video codec standards such as sub-pixel motion estimation and variable-block-size motion estimation.
What is the Influence of News Media on People’s Perception of Corruption? Parametric and Non-Parametric Approaches
Authors: Charron Nicholas , Annoni Paola 
Published: November 2020

AbstractDoes the source of one’s news media have a systematic effect on one’s perception of political corruption? While numerous studies have investigated the extent to which media affects trust in institutions, or the polarization of political values, this study shifts the focus on to how one’s media source conceived here as social media versus traditional media affects the perception of corruption in 2 ways. First, we hypothesize that citizens who consume their news predominately from social media will have higher perceptions of political corruption than consumers of more traditional media sources. Second, we hypothesize that perceptions among social media consumers will be more polarized. Specifically, we argue that the gap in corruption perception between supporters of government and opposition political parties will be larger among social media consumers compared to traditional news consumers. We test our hypotheses using newly collected survey data from the European Quality of Government Index survey from 2017, which contains nearly 78,000 respondents in 21 countries in the European Union. Estimating our model with both parametric and non-parametric approaches, we find robust empirical support for two of our 3 hypotheses.
Workshop report: Toward the development of a human whole stool reference material for metabolomic and metagenomic gut microbiome measurements
Authors: Mandal Rupasri , Cano Raul , Davis Cindy D. , Hayashi David , Jackson Scott A. , Jones Christina M. , Lampe Johanna W. , Latulippe Marie E. , Lin Nancy J. , Lippa Katrice A. , Piotrowski Paulina , Da Silva Sandra M. , Swanson Kelly S. , Wishart David S. 
Published: November 2020

Abstract
Introduction
To date, there has been little effort to develop standards for metabolome-based gut microbiome measurements despite the significant efforts toward standard development for DNA-based microbiome measurements.

Objectives
The National Institute of Standards and Technology (NIST), The BioCollective (TBC), and the North America Branch of the International Life Sciences Institute (ILSI North America) are collaborating to extend NIST’s efforts to develop a Human Whole Stool Reference Material for the purpose of method harmonization and eventual quality control.

Methods
The reference material will be rationally designed for adequate quality assurance and quality control (QA/QC) for underlying measurements in the study of the impact of diet and nutrition on functional aspects of the host gut microbiome and relationships of those functions to health. To identify which metabolites deserve priority in their value assignment, NIST, TBC, and ILSI North America jointly conducted a workshop on September 12, 2019 at the NIST campus in Gaithersburg, Maryland. The objective of the workshop was to identify metabolites for which evidence indicates relevance to health and disease and to decide on the appropriate course of action to develop a fit-for-purpose reference material.

Results
This document represents the consensus opinions of workshop participants and co-authors of this manuscript, and provides additional supporting information. In addition to developing general criteria for metabolite selection and a preliminary list of proposed metabolites, this paper describes some of the strengths and limitations of this initiative given the current state of microbiome research.

Conclusions
Given the rapidly evolving nature of gut microbiome science and the current state of knowledge, an RM (as opposed to a CRM) measured for multiple metabolites is appropriate at this stage. As the science evolves, the RM can evolve to match the needs of the research community. Ultimately, the stool RM may exist in sequential versions. Beneficial to this evolution will be a clear line of communication between NIST and the stakeholder community to ensure alignment with current scientific understanding and community needs.
The influence of preparation methodology on the concentrations of heavy metals in Pleurozium schreberi moss samples prior to use in active biomonitoring studies
Authors: Świsłowski Paweł , Kosior Grzegorz , Rajfur Małgorzata 
Published: November 2020

AbstractActive biomonitoring is used to assess environmental pollution of elements such as heavy metals by indicator species such as mosses. They are used, among others, in urbanized areas where no indicator species are found. In such study areas, mosses collected from sites considered to be ecologically clean shall be exposed. In this context, it is very important to prepare the mosses properly before the exposure, so that the information received about the condition of the environment is reliable. In 2018, studies were conducted in the forested areas of southern Poland—in Opolskie Province. Pleurozium schreberi mosses were used in these studies. Atomic absorption spectrometry with flame atomiser (F-AAS) was used to determine the concentrations of Mn, Fe, Ni, Cu, Zn and Pb present. The aim was to study the influence of preparation methodology on Pleurozium schreberi moss samples prior to use in active biomonitoring studies. Four different methodologies were tested across four different sample locations (with varying levels of pollution). The results of the research were analysed and the coefficient of variation (CV) was determined. The value of the CV is influenced, among other things, by the location of the particular sample and the level of pollution by, for example heavy metals, in the moss. The research conducted proves that of the four methods used to prepare mosses for later exposure in active biomonitoring, the best method is averaging with simultaneous conditioning of mosses in demineralised water. This treatment causes the CV coefficient to fall below 10% for most of the metals determined in the moss samples. It has also been shown that maintaining moss collection methodology in accordance with ICP Vegetation standards (open/wooded area—tree canopy) also has a significant impact on the result obtained. Statistical analysis confirmed (Wilcoxon test) that the method of processing the mosses significantly influenced the results obtained. Thanks to the appropriate preparation of the mosses before exposition, they can be used in active biomonitoring of, for example, urban areas.
Aerosol-Deposited BiVO4 Photoelectrodes for Hydrogen Generation
Authors: Wolpert Charline , Emmler Thomas , Villa Vidaller Maria , Elsenberg Andreas , Shinoda Kentaro , Schieda Mauricio , Gärtner Frank , Akedo Jun , Klassen Thomas 
Published: November 2020

AbstractHydrogen generation from renewable energy sources will play a key role in the concerted endeavor to constrain climate change. One environmentally friendly route, powered by sunlight, is the photoelectrochemical water splitting cell (PEC). This technology employs electrodes coated with thin films of semiconductor materials to capture light and generate charge carriers that directly drive the water splitting reaction. Bismuth vanadate is a promising metal oxide semiconductor, as it absorbs visible light, and is abundant, non-toxic and cost-effective. The present study investigates the formation of bismuth vanadate thin films by the aerosol deposition (AD) method. Operating with layer formation at room temperature, AD offers advantages over other routes for the fabrication of photoactive thin film coatings, as no binders or sintering processes need to be applied. Furthermore, compared to traditional cold spraying, micrometer-sized particles can be used, resulting in coatings with thicknesses below 1 µm. Additionally, the lower kinetic energy of the feedstock powder particles enables the use of delicate substrates, such as FTO-coated glass, expanding the range of possible PEC device configurations. The process parameters explored in this study had considerable influence on the resulting coating microstructure, which in turn showed a significant impact on the photoelectrochemical performance.
Influence of MAX-Phase Deformability on Coating Formation by Cold Spraying
Authors: Elsenberg Andreas , Busato Marco , Gärtner Frank , List Alexander , Bruera Alessia , Bolelli Giovanni , Lusvarghi Luca , Klassen Thomas 
Published: November 2020

AbstractAs solid-state deposition technique avoiding oxidation, cold gas spraying is capable of retaining feedstock material properties in the coatings, but typically fails to build up coatings of brittle materials. Ceramic MAX phases show partial deformability in particular lattice directions and may thus successfully deposit in cold spraying. However, deformation mechanisms under high strain rate, as necessary for cohesion and adhesion, are not fully clear yet. A MAX-phase deposit only builds up, if the specific mechanical properties of the MAX phase allow for, and if suitable spray parameter sets get realized. To investigate the influence of material properties and deposition conditions on coating microstructure and quality, three MAX phases, Ti3SiC2, Ti2AlC and Cr2AlC, were selected. Up to ten passes under different spray parameters yielded Ti2AlC and Cr2AlC coatings with thicknesses of about 200-500 µm. In contrast, Ti3SiC2only forms a monolayer, exhibiting brittle laminar failure of the impacting particles. In all cases, the crystallographic structure of the MAX-phase powders was retained in the coatings. Thicker coatings show rather low porosities (< 2%), but some laminar cracks. The deposition behavior is correlated with individual mechanical properties of the different MAX-phase compositions and is discussed regarding the particular, highly anisotropic deformation mechanisms.
Evaluation of Fluoride and Selected Chemical Parameters in Kombucha Derived from White, Green, Black and Red Tea
Authors: Jakubczyk Karolina , Gutowska Izabela , Antoniewicz Justyna , Janda Katarzyna 
Published: November 2020

AbstractKombucha dates back thousands of years and is reported to have originated in East Asia. It is produced by fermenting tea with added sugar using SCOBY (symbiotic culture of bacteria and yeast). Its health benefits can be attributed to the metabolites produced during the fermentation process. Valuable ingredients of this fermented tea beverage include acetic acid, glucuronic acid, vitamins, enzymes, sugars and polyphenols. Tea, and consequently kombucha, contains numerous minerals, and one of them is fluoride. Under physiological conditions, fluoride plays a significant role in hard tissue mineralisation processes. However, even at low concentrations with long-term exposure, fluorides may accumulate in the body and cause a range of detrimental effects. Kombucha is traditionally brewed with black tea, but these days it is becoming increasingly popular to use other types of tea to make it, which may significantly affect its composition and health-promoting effects. The aim of the study was to evaluate the fluoride content in kombucha beverages derived from black, green, white and red tea. Fluoride content was measured at different time points during fermentation. The potentiometric method was used to determine the content of fluoride ions. It was demonstrated that kombucha is a major dietary source of fluoride (0.42–0.93 mg/L) and that the type of tea used has a significant effect on its chemical composition. Therefore, it recommended to make the beverage with white or red tea, due to the lowest fluoride content and ensure food safety.Graphical Abstract
Scrutinising what Open Access Journals Mean for Global Inequalities
Authors: Demeter Márton , Istratii Ronina 
Published: November 2020

AbstractIn the current article, we tested our hypothesis by which high-impact journals tend to have higher Article Processing Charges (APCs) by comparing journal IF metrics with the OA publishing fees they charge. Our study engaged with both journals in Science, Technology, Engineering and Mathematics (STEM) fields and the Humanities and Social Sciences (HSS) and included Hybrid, Diamond and No OA journals. The overall findings demonstrate a positive relationship between APCs and journals with high IF for two of the subject areas we examined but not for the third, which could be mediated by the characteristics and market environment of the publishers. We also found significant differences between the analysed research fields in terms of APC policies, as well as differences in the relationship between APCs and the IF across periodicals. The study and analysis conducted reinforces our concerns that Hybrid OA models are likely to perpetuate inequalities in knowledge production.