bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nanofibrous Composite with Tailorable Electrical and Mechanical Properties for Cardiac Tissue Engineering
Authors: Roshanbinfar Kaveh , Vogt Lena , Ruther Florian , Roether Judith A. , Boccaccini Aldo R. , Engel Felix B. 
Published: December 2019

AbstractCardiac tissue engineering is a promising strategy to prevent functional deterioration or even to enhance cardiac function upon myocardial infarction. Here, electrospun fiber mats containing different combinations of electrically conductive polyaniline, collagen, and/or hyaluronic acid are assessed regarding material properties and compatibility with cardiomyocyte attachment and function. Microstructure analysis reveals that collagen fiber mats contain a wide range of fiber diameters after crosslinking (from ≈300 nm to ≈5 µm); all other fiber mats contain fibers in the range of ≈120 to ≈300 nm. Fiber mats exhibit comparable electrical conductivity to and greater mechanical properties than the native human myocardium, which is considered beneficial. Cell–matrix interaction analysis utilizing postnatal rat cardiomyocytes reveals that the fiber mats are non‐cytotoxic and permit cell attachment and contraction. Fiber mats containing collagen (9.89%), hyaluronic acid (1.1%), and polyaniline (PANi, 1.34%) exhibit the most favorable properties with longer contraction time, higher contractile amplitude, and lower beating rates. Improved contraction is accompanied by increased connexin 43 expression. Importantly, this fiber mat is a suitable material for human‐induced pluripotent stem cell–derived cardiomyocytes regarding cytotoxicity, cell attachment, and function. Collectively, these data demonstrate that fiber mats made of collagen, hyaluronic acid, and polyaniline are promising materials for cardiac tissue engineering.
Double‐Layered M2e‐NA Protein Nanoparticle Immunization Induces Broad Cross‐Protection against Different Influenza Viruses in Mice
Authors: Wang Ye , Deng Lei , Gonzalez Gilbert X. , Luthra Latika , Dong Chunhong , Ma Yao , Zou Jun , Kang Sang‐Moo , Wang Bao‐Zhong 
Published: December 2019

AbstractThe development of a universal influenza vaccine is an ideal strategy to eliminate public health threats from influenza epidemics and pandemics. This ultimate goal is restricted by the low immunogenicity of conserved influenza epitopes. Layered protein nanoparticles composed of well‐designed conserved influenza structures have shown improved immunogenicity with new physical and biochemical features. Herein, structure‐stabilized influenza matrix protein 2 ectodomain (M2e) and M2e‐neuraminidase fusion (M2e‐NA) recombinant proteins are generated and M2e protein nanoparticles and double‐layered M2e‐NA protein nanoparticles are produced by ethanol desolvation and chemical crosslinking. Immunizations with these protein nanoparticles induce immune protection against different viruses of homologous and heterosubtypic NA in mice. Double‐layered M2e‐NA protein nanoparticles induce higher levels of humoral and cellular responses compared with their comprising protein mixture or M2e nanoparticles. Strong cytotoxic T cell responses are induced in the layered M2e‐NA protein nanoparticle groups. Antibody responses contribute to the heterosubtypic NA immune protection. The protective immunity is long lasting. These results demonstrate that double‐layered protein nanoparticles containing structure‐stabilized M2e and NA can be developed into a universal influenza vaccine or a synergistic component of such vaccines. Layered protein nanoparticles can be a general vaccine platform for different pathogens.
Strategies for Analyzing Noncommon‐Atom Heterovalent Interfaces: The Case of CdTe‐on‐InSb
Authors: Luna Esperanza , Trampert Achim , Lu Jing , Aoki Toshihiro , Zhang Yong‐Hang , McCartney Martha R. , Smith David J. 
Published: December 2019

AbstractSemiconductor heterostructures are intrinsic to a wide range of modern‐day electronic devices, such as computers, light‐emitting devices, and photodetectors. Knowledge of chemical interfacial profiles in these structures is critical to the task of optimizing the device performance. This work presents an analysis of the composition profile and strain across the noncommon‐atom heterovalent CdTe/InSb interface, carried out using a combination of electron microscopy imaging techniques. Because of the close atomic numbers of the constituent elements, techniques such as high‐angle annular‐dark‐field and large‐angle bright‐field scanning transmission electron microscopy, as well as electron energy‐loss spectroscopy, give results from the interface region that are inherently difficult to interpret. By contrast, use of the 002 dark‐field imaging technique emphasizes the interface location by comparing differences in structure factors between the two materials. Comparisons of experimental and simulated CdTe‐on‐InSb profiles reveal that the interface is structurally abrupt to within about 1.5 nm (10–90% criterion), while geometric phase analysis based on aberration‐corrected electron microscopy images reveals a minimal level of interfacial strain. The present investigation opens new routes to the systematic investigation of heterovalent interfaces, formed by the combination of other valence‐mismatched material systems.
Highly Robust, Flexible, and Large‐Scale 3D‐Metallized Sponge for High‐Performance Electromagnetic Interference Shielding
Authors: Lin Sen , Liu Junchen , Wang Qingmin , Zu Di , Wang Haiyang , Wu Fan , Bai Xiaopeng , Song Jianan , Liu Zhenglian , Li Ziwei , Huang Kai , Li Bo , Lei Ming , Wu Hui 
Published: December 2019

AbstractElectromagnetic interference (EMI) is a type of pollution that is caused by the ubiquitous usage of electronic communication in general, and military radar equipment in particular. Even though this is a common problem for a long time, the fabrication of large‐area, flexible, and robust EMI shielding materials is still a challenge today. In this work, the 3D meshing strategy is simulated for most efficient utilization of metallic silver for X‐band EMI shielding, and propose a roll‐to‐roll (R2R) process to fabricate robust, flexible, and large‐scale EMI shielding sponge, silver nanowires/polyvinyl butyral (PVB) melamine sponge (AgPMS). Typically, 0.5 cm thick sponge has about 60 dB total EMI shielding efficiency (SE) in the microwave band, which is higher than for commercial EMI shielding sponges (about 45 dB) of the same thickness. AgPMS shows unchanged electrical properties after 1000 compression and bending cycles. Moreover, a AgPMS garment is made to demonstrate the excellent EMI shielding performance and remarkable flexibility of this material. Those properties suggest that AgPMS can be readily applied in challenging environments like hospitals, military installations, remote communication centers, and for any devices with curved surfaces.
A Flexible, Recyclable, and High‐Performance Pullulan‐Based Triboelectric Nanogenerator (TENG)
Authors: Lu Yuanchao , Li Xunjia , Ping Jianfeng , He Jin‐song , Wu Jian 
Published: December 2019

AbstractThe developments of natural biomaterials‐based triboelectric nanogenerators (TENGs) have been emerged with the extensive and promising requirements in biomedical and biowearable fields due to the properties of renewability, cost‐effectivity, biocompatibility, and biodegradability. In this work, a flexible, recyclable, and high‐performance pullulan‐based TENG, fabricated with pullulan and other additives, is developed. Based on the open‐circuit voltage, the thickness and the additives of pullulan‐based TENGs are optimized. The maximum open‐circuit voltage, 79 V, under 10 Hz motion frequency and 10 W loading power is obtained in the NaF‐pullulan TENG. And the optimal output power density is 41.7 mW m−2 under 7 MΩ loading resistance. Then, practical applications of the as‐fabricated pullulan‐based TENGs on lighting LED arrays and monitoring hand bending movements are successfully investigated, presenting the feasibility of powering electric devices and acting as wearable devices. Finally, the excellent recyclability of the P‐P film is illustrated by the excellent TENG performance within five‐times recycles. Thus, the recyclability and facile fabrication procedures of the pullulan‐based TENGs could provide a potential prospect in the next‐generation biowearable devices and energy harvesters.
High‐Performance Platinum‐Perovskite Composite Bifunctional Oxygen Electrocatalyst for Rechargeable Zn–Air Battery
Authors: Wang Xixi , Sunarso Jaka , Lu Qian , Zhou Ziling , Dai Jie , Guan Daqin , Zhou Wei , Shao Zongping 
Published: December 2019

AbstractConstructing highly active electrocatalysts with superior stability at low cost is a must, and vital for the large‐scale application of rechargeable Zn–air batteries. Herein, a series of bifunctional composites with excellent electrochemical activity and durability based on platinum with the perovskite Sr(Co0.8Fe0.2)0.95P0.05O3−δ (SCFP) are synthesized via a facile but effective strategy. The optimal sample Pt‐SCFP/C‐12 exhibits outstanding bifunctional activity for the oxygen reduction reaction and oxygen evolution reaction with a potential difference of 0.73 V. Remarkably, the Zn–air battery based on this catalyst shows an initial discharge and charge potential of 1.25 and 2.02 V at 5 mA cm−2, accompanied by an excellent cycling stability. X‐ray photoelectron spectroscopy, X‐ray absorption near‐edge structure, and extended X‐ray absorption fine structure experiments demonstrate that the superior performance is due to the strong electronic interaction between Pt and SCFP that arises as a result of the rapid electron transfer via the PtOCo bonds as well as the higher concentration of surface oxygen vacancies. Meanwhile, the spillover effect between Pt and SCFP also can increase more active sites via lowering energy barrier and change the rate‐determining step on the catalysts surface. Undoubtedly, this work provides an efficient approach for developing low‐cost and highly active catalysts for wider application of electrochemical energy devices.
Solidarity and disparity: Declining labor union density and changing racial and educational mortality inequities in the United States
Authors: Eisenberg‐Guyot Jerzy , Mooney Stephen J. , Hagopian Amy , Barrington Wendy E. , Hajat Anjum 
Published: December 2019

AbstractBackgroundRecently, United States life expectancy has stagnated or declined for the poor and working class and risen for the middle and upper classes. Declining labor‐union density—the percent of workers who are unionized—has precipitated burgeoning income inequity. We examined whether it has also exacerbated racial and educational mortality inequities.MethodsFrom CDC, we obtained state‐level all‐cause and overdose/suicide mortality overall and by gender, gender‐race, and gender‐education from 1986–2016. State‐level union density and demographic and economic confounders came from the Current Population Survey. State‐level policy confounders included the minimum wage, the generosity of Aid to Families with Dependent Children or Temporary Assistance for Needy Families, and the generosity of unemployment insurance. To model the exposure‐outcome relationship, we used marginal structural modeling. Using state‐level inverse‐probability‐of‐treatment‐weighted Poisson models with state and year fixed effects, we estimated 3‐year moving average union density’s effects on the following year’s mortality rates. Then, we tested for gender, gender‐race, and gender‐education effect‐modification. Finally, we estimated how racial and educational all‐cause mortality inequities would change if union density increased to 1985 or 1988 levels, respectively.ResultsOverall, a 10% increase in union density was associated with a 17% relative decrease in overdose/suicide mortality (95% confidence interval [CI]: 0.70, 0.98), or 5.7 lives saved per 100 000 person‐years (95% CI: −10.7, −0.7). Union density's absolute (lives‐saved) effects on overdose/suicide mortality were stronger for men than women, but its relative effects were similar across genders. Union density had little effect on all‐cause mortality overall or across subgroups, and modeling suggested union‐density increases would not affect mortality inequities.ConclusionsDeclining union density (as operationalized in this study) may not explain all‐cause mortality inequities, although increases in union density may reduce overdose/suicide mortality.
Current work hours and coronary artery calcification (CAC): The Multi‐Ethnic Study of Atherosclerosis (MESA)
Authors: Allison Penelope J. , Jorgensen Neal W. , Fekedulegn Desta , Landsbergis Paul , Andrew Michael E. , Foy Capri , Hinckley Stukovsky Karen , Charles Luenda E. 
Published: December 2019

AbstractBackgroundLong work hours may be associated with adverse outcomes, including cardiovascular disease. We investigated cross‐sectional associations of current work hours with coronary artery calcification (CAC).MethodsParticipants (n = 3046; 54.6% men) were from the Multi‐Ethnic Study of Atherosclerosis. The number of hours worked in all jobs was obtained by questionnaire and CAC from computed tomography. The probability of a positive CAC score was modeled using log‐binomial regression. Positive scores were modeled using analysis of covariance and linear regression.ResultsSixteen percent of the sample worked over 50 hours per week. The overall geometric mean CAC score was 5.2 ± 10.0; 40% had positive scores. In fully‐adjusted models, prevalence ratios were less than 40 hours: 1.00 (confidence interval [CI]: 0.88‐1.12), 40:(ref), 41 to 49:1.13 (CI: 0.99‐1.30), and ≥50:1.07 (CI: 0.94‐1.23) and longer current work hours were not associated with higher mean CAC scores (<40:56.0 [CI: 47.3‐66.3], 40:57.8 [CI: 45.6‐73.3], 41 to 49:59.2 [CI: 45.2‐77.6], ≥50:51.2 [CI: 40.5‐64.8]; P = .686).ConclusionsCurrent work hours were not independently associated with CAC scores.
Holoprosencephaly in Kabuki syndrome
Authors: Daly Tara , Roberts Abra , Yang Edward , Mochida Ganeshwaran H. , Bodamer Olaf 
Published: December 2019

AbstractKabuki syndrome is a rare, multi‐systemic disorder of chromatin regulation due to mutations in either KMT2D or KDM6A that encode a H3K4 methyltransferase and an H3K27 demethylase, respectively. The associated clinical phenotype is a direct result of temporal and spatial changes in gene expression in various tissues including the brain. Although mild to moderate intellectual disability is frequently recognized in individuals with Kabuki syndrome, the identification of brain anomalies, mostly involving the hippocampus and related structures remains an exception. Recently, the first two cases with alobar holoprosencephaly and mutations in KMT2D have been reported in the medical literature. We identified a de novo, pathogenic KMT2D variant (c.6295C > T; p.R2099X) using trio whole‐exome sequencing in a 2‐year‐old female with lobar holoprosencephaly, microcephaly and cranio‐facial features of Kabuki syndrome. This report expands the spectrum of brain anomalies associated with Kabuki syndrome underscoring the important role of histone modification for early brain development.
Stable Salts of Heteroleptic Iron Carbonyl/Nitrosyl Cations
Authors: Bohnenberger Jan , Krossing Ingo 
Published: December 2019

AbstractThe oxidation of Fe(CO)5 with the [NO]+ salt of the weakly coordinating perfluoroalkoxyaluminate anion [F‐{Al(ORF)3}2]− (RF=C(CF3)3) leads to stable salts of the 18 valence electron (VE) species [Fe(CO)4(NO)]+ and [Fe(CO)(NO)3]+ with the Enemark–Feltham numbers of {FeNO}8 and {FeNO}10. This finally concludes the triad of heteroleptic iron carbonyl/nitrosyl complexes, since the first discovery of the anionic ([Fe(CO)3(NO)]−) and neutral ([Fe(CO)2(NO)2]) species over 80 years ago. Both complexes were fully characterized (IR, Raman, NMR, UV/Vis, scXRD, pXRD) and are stable at room temperature under inert conditions over months and may serve as useful starting materials for further investigations.
Highly conductive polymer composites with excellent toughness, fluidity and temperature‐independent conductivity
Authors: Li Guanglin , Xia Honglei , Lei Yajie , Yang WenBin , Liu Tao , He JiangPing 
Published: December 2019

ABSTRACTConductive polymer composites of low melting point metal/ high melting point metal/polymer were prepared by melt mixing and investigated the effects of Sn‐to‐Cu content ratio on the microstructure and properties of Sn/Cu/PA6 ternary composites with a metal content of 53.3 vol %. The results show that Sn reacts with Cu to form intermetallic compounds during melting processing. WhenVSn/VCuis less than 1.5, the metal phase is a solid. However, ifVSn/VCuis higher than 1.5, the metal phase is a suspension. AsVSn/VCuincreases, the morphology of metal phase changes from “islands” to physically continuous networks, and the Volume resistivity, impact strength and complex viscosity of the composites can reach 1.11 × 10−4Ω cm, 3.8 kJ/m2and 2.4 × 103 Pa s, respectively. Moreover, the resistivity of the composites with physically continuous networks is almost independent of temperature. The combination of low and high melt point metals can be considered as a useful strategy to prepare conductive polymer composites with high performance. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2020,137, 48820.
Simultaneous removal of Cd, Co, Cu, Mn, Ni, and Zn from synthetic solutions on a hemp‐based felt. III. Real discharge waters
Authors: Morin‐Crini Nadia , Staelens Jean‐Noël , Loiacono Sonia , Martel Bernard , Chanet Gilles , Crini Grégorio 
Published: December 2019

ABSTRACTTwo hemp‐based materials were used as nonconventional adsorbents for the final treatment of industrial discharge waters (DWs) from a metal‐finishing plant. The first adsorbent, referred as HEMP, was a felt made of 100% hemp fiber. The second was the same felt coated with a maltodextrin‐1,2,3,4‐butanetetracarboxylic crosslinked polymer (HEMPM) in order to provide ion‐exchange properties to the material by introducing carboxylic groups. The batch experiments showed that both materials exhibited high adsorption capacities toward metal ions present in 12 DWs, leading to concentrations well below those allowed by the French regulation. Measurements of the germination rate ofLactuca sativaseeds and of mobility inhibition ofDaphnia magna, used as ecotoxicological tests, were carried out on DWs before and after hemp treatment. The average germination rate before and after treatment were 47.2 ± 4.1 for untreated DWs, 71.2 ± 6.3 for DWs treated by HEMP, and 89.3 ± 4.7 for DWs treated by HEMPM. The EC50 values for four DWs were between 2.1 and 10.4% of DW, indicating high toxicity. After HEMPM treatment, exposure to the DW for 24 h did not cause immobilization (EC50 > 90%). © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2020,137, 48823.
Density reduction behaviors and cell morphology in extrusion of LLDPE/wood fiber composites with physical and chemical blowing agents
Authors: Guo Gangjian 
Published: December 2019

ABSTRACTFoamed wood fiber/plastic composites (WPC) with a fine‐cell structure offer many benefits compared with the unfoamed WPC, such as the reduced material cost and density, the improved toughness, and the enhanced processability. However, it is extremely challenging to achieve the desired density reduction and obtain a fine‐cell structure simultaneously. One of the obstacles is that the volatiles released from the wood fiber (WF) during processing should be suppressed to ensure a fine‐cell structure. Linear low‐density polyethylene (LLDPE) has a relatively low melting temperature, and it can reduce the processing temperature and suppress volatiles when used as a polymer matrix for foamed WPC. This paper systematically investigates the foamability of LLDPE/WF composites in a continuous foam extrusion, with both a chemical blowing agent and a physical blowing agent (PBA). It turns out that the PBA‐based foaming led to a smaller cell size and a narrower cell size distribution. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48829.
Preparation of planar and hydrophobic benzocyclobutene‐based dielectric material from biorenewable rosin
Authors: Fu Fei , Wang Dan , Shen Minggui , Shang Shibin , Song Zhanqian , Song Jie 
Published: December 2019

ABSTRACTA rosin‐based monomer with thermally crosslinkable benzocyclobutene groups was synthesized in this study. The structure of the monomer was examined using mass spectroscopy, Fourier transform infrared spectroscopy, and nuclear magnetic resonance spectroscopy. An amorphous crosslinked network with dielectric constant of 2.71 and dielectric loss of 0.0012 at 30 MHz was formed when the monomer was polymerized at high temperature (> 200 °C). The polymer film exhibits surface roughness (Ra) of 0.337 nm in a 5.0 × 5.0 μm2 area and the water contact angle of 110°. In addition, results from thermogravimetric analysis indicate that the polymer has T5% = 402 °C, and differential scanning calorimetry measurements show that the glass transition temperature is at least 350 °C. Results from nanoindentation tests show that the hardness and Young's modulus of the polymer are 0.418 and 4.728 GPa, respectively. These data suggest that this new polymer may have potential applications in electronics and microelectronics. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48831.
Smith‐Lemli‐Opitz syndrome — Fetal phenotypes with special reference to the syndrome‐specific internal malformation pattern
Authors: Schoner Katharina , Witsch‐Baumgartner Martina , Behunova Jana , Petrovic Robert , Bald Rainer , Kircher Susanne G. , Ramaswamy Annette , Kluge Britta , Meyer‐Wittkopf Matthias , Schmitz Ralf , Fritz Barbara , Zschocke Johannes , Laccone Franco , Rehder Helga 
Published: December 2019

AbstractBackgroundAutosomal‐recessive SLOS is caused by mutations in the DHCR7 gene. It is defined as a highly variable complex of microcephaly with intellectual disability, characteristic facies, hypospadias, and polysyndactyly. Syndrome diagnosis is often missed at prenatal ultrasound and fetal autopsyMethodsWe performed autopsies and DHCR7 gene analyses in eight fetuses suspected of having SLOS and measured cholesterol values in long‐term formalin‐fixed tissues of an additional museum exhibitResultsFive of the nine fetuses presented classical features of SLOS, including four cases with atrial/atrioventricular septal defects and renal anomalies, and one with additional bilateral renal agenesis and a Dandy‐Walker cyst. These cases allowed for diagnosis at autopsy and subsequent SLOS diagnosis in two siblings. Two fetuses were mildly affected and two fetuses showed additional holoprosencephaly. These four cases and the exhibit had escaped diagnosis at autopsy. The case with bilateral renal agenesis presented a novel combination of a null allele and a putative C‐terminus missense mutation in the DHCR7 geneConclusionsIn view of the discrepancy between the prevalence of SLOS among newborns and the carrier frequency of a heterozygous DHCR7 gene mutation, the syndrome‐specific internal malformation pattern may be helpful not to miss SLOS diagnosis in fetuses at prenatal ultrasound and fetal autopsy