bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH FAKTOR PERSONAL TERHADAP KOMITMEN ORGANISASIONAL GURU MADRASAH
Authors: Akbar Rofiq Faudy 
Published: August 2020

<p><em>This study aims to examine the influence of personal factors on organizational commitment. Personal factors in this study are interpreted with job choice factor, expectancy, and psychological contract variables. Research respondents were private madrasa teachers in the Central Java Indonesia. Data analysis using structural equation modeling partial least square shows that personal factors have a positive and significant effect on teacher organizational commitment. Job choice factor is the consideration of the applicant the first time someone decides to work as a teacher. Individuals have evaluated salary, the nature of the type of work as an educator, as well as long-term prospects such as the possibility to become permanent teachers of a madrasa / school and the opportunity to get certified. Teachers have expectations regarding financial and non-financial compensation and hope the head of the madrasa or foundation provides reciprocity or appreciation for their sacrifice to the organization. Teachers always expect a positive response from the </em><em> </em><em>head of the madrasa/foundation, as their workload increases. Positive responses from the head of the madrasa/foundation provided their commitment to work and organization will always increase</em><em>, c</em><em>onversely</em><em>.</em><em> </em></p><p> </p>
Analysis of the Effectiveness of Variants of the Exhaust Compartment of a Steam Turbine
Authors: Solodov V. G. , Konev V. A. 
Published: August 2020

The results of a numerical study of the gas-dynamic and power characteristics of the exhaust compartment of low-pressure cylinder, including the last stage with a blade of 1100 mm length and the exhaust path, in terms of their interaction are presented. Numerical models of exhaust compartment variants, including steam extraction in front of last stage diaphragm, two steam suctions from the interring gap with a dehumidification chamber, above-band leakages, steam injection from the dehumidification chamber into the diffuser channel have been developed. The flow in each computational subdomain is described by the complete system of non-stationary Reynolds – Favre equations averaged by Navier – Stokes. Turbulent effects are described with the SST Menter model in the stage, and with the modified Spalart – Allmaras turbulence model in the path. The integration of system of equations was carried out using an author’s software package. The calculated subdomains were approximated by hexagonal grids. The solver used an implicit difference TVD-scheme of finite volumes of the 2nd order of accuracy based on the solution of the Riemann problem. A variant of the algorithm based on splitting the computational process for multiprocessor platforms was used in the calculation. The model of stage used an averaging the mass, momentum and energy fluxes in the circumferential direction in the interstage gap. One channel of the diaphragm with a pre-connected fragment, as well as one channel of the working ring and the flow in the branch pipe were calculated. Parameters were exchanged between the stage and the branch pipe on the basis of mass flow averaging. The calculations were based on a table model of wet steam in the approximation of equilibrium condensation. The variants of improvement of the flow part of the exhaust compartment were considered. A study of the operation of the compartment options for the nominal mode of the K-220-44-2M turbine of the Loviisa nuclear power plant was performed. The effectiveness of lowering the cap of the collecting chamber, controlling the flow using sheet ribs above the diffuser shell, expanding the collecting chamber in the plane of the horizontal connector, and ensuring the release of excess steam from the moisture removal chamber through the tangential slots in the lower half of the convex shell of the diffuser were analyzed.
The Reduction in CD8+PD-1+ T Cells in Liver Histological Tissue is Related to Pegylated IFN-α Therapy Outcomes in Chronic Hepatitis B Patients
Authors: Liu Ruyu , Chen Yanhui , Guo Jiang , Li Minghui , Lu Yao , Zhang Lu , Shen Ge , Wu Shuling , Chang Min , Hu Leiping , Hao Hongxiao , Zhang Henghui , Xie Yao 
Published: August 2020

Abstract
Background: Antiviral therapy is recommended for patients with immune-active chronic hepatitis B (CHB) to decrease the risk of liver-related complications. However, the outcomes of the pegylated IFN-α (PEG-IFN-α) therapy vary among CHB patients. We aimed to identify factors that can influence the outcomes in CHB patients who received antiviral PEG-IFN-α monotherapy.Methods: Thirty-two CHB patients who received PEG-IFN-α monotherapy were enrolled in this study. All of the patients underwent two liver biopsies at baseline and 6 months after the initiation of the therapy. CD8 + T cells, CD4 + T cells, CD68 + mononuclear cells, and PD-1 levels in the 64 liver biopsy specimens were examined via immunofluorescence.Results: The overall median frequency of CD8 + T cells in the liver tissues of 32 CHB patients significantly decreased at 6 months after the therapy initiation ( p < 0.01). In the FIER (fibrosis and inflammation response with HBeAg seroconversion) group, CD8 + PD-1 + T cells significantly decreased at 6 months ( p < 0.05), while CD8 + PD-1 - T cells had no significant difference. On the contrary, in the FIENR (no fibrosis and inflammation response and HBeAg seroconversion) group, CD8 + PD-1 - T cells significantly decreased after 6 months of PEG-IFN-α treatment ( p < 0.05), while CD8 + PD-1 + T cells had no significant difference. In addition, the levels of CD68 + mononuclear cells in the FIER group showed an overall increasing trend after treatment ( p < 0.05).Conclusions: The changes in the levels of CD8 + PD-1 + T cells and CD68 + mononuclear cells may be related to the response to PEG-IFN-α therapy.
Nosocomial Tuberculosis Transmission from 2006 to 2018 in Beijing Chest Hospital, China
Authors: XIE ZHONGYAO , ZHOU NING , CHI YUQING , HUANG GUOFANG , WANG JINGPING , GAO HUI , XIE NA , MA QIANHUI , YANG NAN , Nie Wenjuan , Sun Zhaogang , CHU NAIHUI 
Published: August 2020

Abstract
Background: Strong evidence is lacking to support effectiveness of currently implemented tuberculosis infection prevention control (TB-IPC) measures for preventing nosocomial tuberculosis (TB) transmission. This 13-year analysis is the longest follow-up investigation to date to identify risk factors underlying nosocomial TB transmission. Methods: We monitored all staff of Beijing Chest Hospital each year from 2006 to 2018. Age, gender, duration, department, education, income, respirator, ultraviolet, and ventilation were chosen as variables. Univariate cox regression, correlation analysis, and multivariate cox regression were analyzed sequentially.Results: Using multivariable cox regression analysis, variables of income, ultraviolet germicidal irradiation (UVGI), natural ventilation and mechanical ventilation conferred significant protective effects, with odds ratios (ORs) of 0.499, 0.058, 0.003, and 0.015, respectively (PI<0.05). Medical N95 respirator conferred an excellent protective effect, with an associated TB infection rate of 0%. Notably, inadequately maintained mechanical ventilation systems were less protective than natural ventilation systems.Conclusions: UVGI, adequate ventilation, and medical N95 respirator use may be protective factors against nosocomial TB transmission. Adequate ventilator system training, monitoring, and regular maintenance are critical for achieving effective TB-IPC.
Peri-acetabular bone remodelling after uncemented total hip arthroplasty with monoblock press-fit cups: an observational study
Authors: Anderl Conrad , Mattiassich Georg , Ortmaier Reinhold , Steinmair Martin , Hochreiter Josef 
Published: August 2020

Abstract
Background: Bone stock preservation in total hip replacement is essential to allow for later revisions in an increasingly younger and fitter index patient population. While contemporary modular press-fit acetabular cups lead to rigid fixation with equatorial stress and central osteolysis, more elastic fixation may cause different peri-acetabular bone remodelling. The purpose of this study was to investigate changes in peri-acetabular bone mineral density (BMD) in uncemented elastic fixation with monoblock press-fit cups.Methods: This prospective observational study included 45 patients with monoblock cups. We evaluated peri-acetabular BMD using dual-energy X-ray absorptiometry and reported functional outcomes and complications.Results: At a mean follow-up of 24.2 ± 2.2 months, we found that BMD stabilised in DeLee and Charnley zones I and III and recovered to baseline value in zone II. The mean Harris Hip Scores improved significantly from 56.9 ± 20.0 to 97.2 ± 4.0 (p < 0001). Other than one peri-operative dislocation, we saw no post-operative complications.Conclusions: We found favourable adaptive bone changes with BMD stabilisation in the equatorial zones and recovery to pre-operative values in the central zone. Additionally, excellent clinical outcomes and few prosthesis-related complications strengthened the favourable results of monoblock acetabular cups.Trial registration: Registration number DRKS00017076.
Estimation of Bulk Permittivity of the Moon’s Surface Using Lunar Radar Sounder On-board Selenological and Engineering Explorer
Authors: Hongo Keigo , Toh Hiroaki , Kumamoto Atsushi 
Published: August 2020

Abstract
Site-dependent bulk permittivities of the lunar uppermost media with thicknesses of tens to hundreds meters were estimated based on the data from Lunar Radar Sounder onboard the Selenological and Engineering Explorer (SELENE). It succeeded in sounding almost all over the Moon’s surface in a frequency range around 5 MHz to detect subsurface reflectors beneath several lunar maria. However, it is necessary to estimate the permittivity of the surface regolith of the Moon in order to determine the actual depths to those reflectors instead of apparent depths assuming a speed of light in the vacuum. In this study, we determined site-dependent bulk permittivities by two-layer models consisting of a surface regolith layer over a half-space with uniform but different physical properties from the layer above. Those models consider the electrical conductivity as well as the permittivity, whose trade-off was resolved by utilizing the correlation between iron-titanium content and measured physical properties of lunar rock samples. Distribution of the iron-titanium content on the Moon’s surface had already been derived by spectroscopic observation from SELENE as well. Four lunar maria, Mare Serenitatis, Oceanus Procellarum, Mare Imbrium, and Mare Crisium, were selected as regions of evident reflectors, where we estimated the following four physical properties of each layer, i.e., bulk permittivity, porosity, loss tangent and electrical conductivity to conclude the actual depths of the reflectors are approximately 200m on average. The bulk permittivity ranges from 2.96 at Mare Imbrium to 6.37 at Oceanus Procellarum, whereas the porosity takes the values between 1.8% to 41.1% in the respective maria. It was found that although the bulk permittivity of the four lunar maria differs from a mare to a mare, it shows a good correlation with their composition, viz., their iron-titanium content.
A Nomogram based on a Patient-reported Outcomes Measure: Predicting the Risk of Readmission for Patients with Chronic Heart Failure
Authors: Han Qiang , Ren Jia , Tian Jing , Yang Hong , Zhang Qing , Wang Ruoya , Zhao Jinghua , Han Linai , Li Chenhao , Yan Jingjing , Wang Ke , Zheng Chu , Han Qinghua , Zhang Yanbo 
Published: August 2020

Abstract
Background

Health-related quality of life, evaluated by a patient-reported outcomes measure, is an important prognostic marker in patients with chronic heart failure. This study aimed to use PROM to establish an effective readmission nomogram for chronic heart failure.

Methods

Using patient-reported outcomes measure as a measurement tool, we conducted a readmission nomogram for chronic heart failure on a prospective observational study comprising 454 patients with chronic heart failure hospitalized between May 2017 to January 2020. Concordance index and calibration curve were used to evaluate the discriminative ability and predictive accuracy of the nomogram. A bootstrap resampling method was used for internal validation of results.

Results

The median follow-up period in the study was 372 days. After a final COX regression analysis, the gender, income, health care, appetite-sleep, anxiety, depression, paranoia, support, and independence were identified and included in the nomogram. The nomogram showed moderate discrimination, with concordance index of 0.737 (95% CI 0.673-0.800). The calibration curves for the probability of readmission for patients with chronic heart failure showed high consistency between the probability, as predicted, and the actual probability.

Conclusions

This model offers a platform to assess the risk of readmission for different populations with CHF and can assist clinicians with personalized treatment recommendations.
Upregulated Expression of LncRNA Nicotinamide Nucleotide Transhydrogenase Antisense RNA 1 is Correlated with Unfavorable Clinical Outcomes in Cancers
Authors: Zhang Chenghao , Ren Xiaolei , Liu Zhongyue , Tu Chao 
Published: August 2020

Abstract
Background: The nicotinamide nucleotide transhydrogenase antisense RNA 1 (NNT-AS1) is a long non-coding RNA aberrantly expressed in human malignancies. We aimed to analyze available data to evaluate the correlation between NNT-AS1 expression and cancer prognosis. Methods: Literature retrieval was performed by systematic searching related databases from inception to April 2, 2020. Studies regarding correlation between NNT-AS1 expression, survival outcomes and clinical characteristics of cancer patients were collected and pooled to calculate the the hazard ratios (HRs) or odds ratios (ORs) with 95% confidence intervals (95% CIs). Results: Ten studies comprising 699 patients were included, all of which were conducted in China according to literature selection criteria. Overexpression of NNT-AS1 had a significant association with unfavorable overall survival (OS) (HR=2.08, 95% CI: 1.84-2.36, P<0.001). Stratified analysis showed that tumor type, sample size, follow-up months, and survival analysis approach did not change the predictive value of NNT-AS1 on OS. Furthermore, elevated NNT-AS1 level had significant association with distant metastasis (DM) (OR=2.45, 95% CI: 1.39-4.30), lymph node metastasis (LNM) (OR=3.92, 95% CI: 1.35-11.41), TNM stage (OR=4.25, 95% CI: 1.71-10.56), and vascular invasion (OR=3.98, 95% CI: 2.06-7.71), but was not associated with age and gender. The TCGA dataset further consistently showed that the NNT-AS1 expression was associated with poor OS and disease-free survival. Conclusions: High expression of NNT-AS1 is associated with unfavorable survival outcomes and poor clinicopathologic characteristics. However, large-cohort data and geographical studies are still needed to further validate the prognostic value of NNT-AS1 in cancers.
Does the IOFix implant Improve Union Rates?
Authors: segal david , Ohana Nissim , Nyska Meir , Palmanovich Ezequiel 
Published: August 2020

Abstract
BACKGROUND First metatarso-phalangeal joint fusion is the current gold standard for severe hallux rigidus. Data regarding the union rate and the re-operation rate when IOFix (an Intra-osseous fixation device, Extremity medical, New Jersey, USA) is used for hallux rigidus fusion is limited but promising. The aim of this study was to review our outcomes with the IOFix implant. METHODS We have conducted a retrospective chart review, following the approval of the hospital IRB committee. Exclusion criteria included bilateral operations on the same patient, multiple surgeries, charcot foot or other structural foot abnormalities (except hallux valgus), rheumatoid arthritis and a recent foot trauma. We collected demographic data, physical examination documentation, functional score evaluations (AOFAS), and Plain radiographic studies. RESULTS Thirty patients were included in the study. The mean age was 60.36±9.12 (range 36 to 77) years, 18 (60%) female patients and 12 (40%) male. Fourteen (53.33%) were left side pathologies. The average follow up period was 36.2±12.31 (range 12 to 54) months. Union was obtained in 28 (93.33%) patients, of whom none had requested a hardware removal due to a prominent hardware during a minimum of 2 year follow up period. The mean postoperative AOFAS score was 80.5±10.87 (range 35 to 90). A more stringent inclusion criteria and fusion definitions would have led to an exclusion of two more patients and a dropout of two patients from the “fused” group, which would have led to a fusion rate of 85.71%.CONCLUSIONS This is the largest series of hallux rigidus patients that were operated with an IOFix device. The rates of fusion and hardware removal in MTPJ1 arthrodesis performed with an IOFix implant were found to be similar at most when compared to previously described rates that were obtained with other cheaper and more simple fixation devices.LEVEL OF EVIDENCE: 4
Enhanced aging and thermal shock performance of Mn1.95-xCo0.21Ni0.84SrxO4 NTC ceramics
Authors: Li Haibing , Zhang H.M. , Thayil Islla P Ley , Chang Aimin , Sang Xu , Ma Xiuhua 
Published: August 2020

Abstract
Herein, the Mn1.95-xCo0.21Ni0.84SrxO4 (MCNS) (0 ≤ x ≤ 0.15) based negative temperature coefficient (NTC) materials are prepared by co-precipitation method. The replacement of Mn by Sr plays a critical role in controlling the lattice parameter, relative density, microstructure and electrical properties. The lattice parameter and relative density increase with the increase of Sr content. A small amount of Sr restrains the grain growth and increases the bulk density. Moreover, the ρ25, B25/50, Ea and α values of MCNS ceramics are influenced by the Sr content and ranged from 1535.0-2053.6 Ω·cm, 3654-3709 K, 0.3149-0.3197 eV and -4.111--4.173%, respectively. The XPS results explain the transformation of MCNS ceramics from n- to p-type semiconductors. The conduction could arise from the hopping polaron between Mn3+/Mn4+ and Co2+/Co3+ in the octahedral sites. Furthermore, the aging coefficient (△R/R) of MCNS ceramics is found to be < 0.2%, which indicates the stable distribution of cations in the spinel. Finally, the MCNS ceramics demonstrate excellent thermal durability with <1.3% of resistance shift after 100 thermal shock cycles.
Validation of APACHE II, APACHE III and SAPS II scores in short- and long-term mortality prediction in a mixed intensive care unit in Poland: a cohort study
Authors: Czajka Szymon , Ziębińska Katarzyna , Marczenko Konstanty , Posmyk Barbara , Szczepańska Anna , Krzych Łukasz 
Published: August 2020

Abstract
Background. There are several scores used for in-hospital mortality prediction in critical illness. Their application in a local scenario requires validation to ensure appropriate diagnostic accuracy. Moreover, their use in assessing post-discharge mortality in intensive care unit (ICU) survivors has not been extensively studied. We aimed to validate APACHE II, APACHE III and SAPS II scores in short- and long-term mortality prediction in a mixed adult ICU in Poland. APACHE II, APACHE III and SAPS II scores, with corresponding predicted mortality ratios, were calculated for 303 consecutive patients admitted to a 10-bed ICU in 2016. Short-term (in-hospital) and long-term (12-month post-discharge) mortality was assessed.Results. Median APACHE II, APACHE III and SAPS II scores were 19 (IQR 12-24), 67 (36.5-88) and 44 (27-56) points, with corresponding in-hospital mortality ratios of 25.8% (IQR 12.1-46.0), 18.5% (IQR 3.8-41.8) and 34.8% (IQR 7.9-59.8). Observed in-hospital mortality was 35.6%. Moreover, 12-month post-discharge mortality reached 17.4%. All the scores predicted in-hospital mortality (p<0.05): APACHE II (AUC=0.78; 95%CI 0.73-0.83), APACHE III (AUC=0.79; 95%CI 0.74-0.84) and SAPS II (AUC=0.79; 95%CI 0.74-0.84); as well as mortality after hospital discharge (p<0.05): APACHE II (AUC=0.71; 95%CI 0.64-0.78), APACHE III (AUC=0.72; 95%CI 0.65-0.78) and SAPS II (AUC=0.69; 95%CI 0.62-0.76), with no statistically significant difference between the scores (p>0.05). The calibration of the scores was good.Conclusions. All the scores are acceptable predictors of in-hospital mortality. In the case of post-discharge mortality, their diagnostic accuracy is lower and of borderline clinical relevance. Further studies are needed to create scores estimating the long-term prognosis of subjects successfully discharged from the ICU.
Transcriptome Analysis Reveals Candidate Genes During the Prepupal-pupal Transition in the Oriental Armyworm, Mythimna separata (Walker) (Lepidoptera: Noctuidae)
Authors: Li Peirong , Li Xinru , Wang Wei , Tan Xiaoling , Wang Xiaoqi , Yang Xueqing 
Published: August 2020

Abstract
Background

Metamorphosis ensures the transformation of a larva of the holometabolous insects into a reproductive adult through a transitory pupal stage. Understanding how changes in expression levels of genes during the prepupal-pupal transition will inform us of how the metamorphosis arises.
Results

In this study, mature larvae (ML), wandering (W), 1 day (P1), 5 days (P5), and 10 days (P10) after pupation of the Mythimna separata (Walker), a notorious migratory pest of agricultural crops, were selected, forming five groups. RNA-Seq revealed that the draft transcriptome assembly contained 140562 contigs, and more than half (74,059) were similar to sequence at NCBI (e value < e− 3), including 22884, 23534, 26643, and 33238 differentially expressed genes (DEGs) in ML vs W, W vs P1, P1 vs P5, and P5-vs-P10, respectively. Comparative transcriptomics revealed the enrichment of biological processes related to the membrane and integral component of membrane, which includes the cuticular protein (CP), 20-hydroxyecdysone (20E), and juvenile hormone (JH) biosynthesis, enabled us to delineate and partially validate the metabolic pathway in M. separata. Of these DEGs, 33 CP, 18 20E, and 7 JH genes were differentially expressed across the developmental stages. Correlation analysis uncovered that the relative expression levels of 10 selected CP, 20E, and JH-related genes obtained by real-time PCR quantitative (RT-qPCR) matched well with their FPKM values derived from RNA-seq.
Conclusions

The data gave here represent an important first step to uncover the molecular mechanism of metamorphosis in M. separata, which also provide valuable information for manipulation of insect development and metamorphosis using the obtained DEGs as targets and broaden the applications of available tools for insect pest control.