bluuebunny/crossref_metadata_2025_split huggingface dataset:
High prevalence of hip and groin problems in professional ice hockey players, regardless of playing position
Authors: Wörner Tobias , Thorborg Kristian , Eek Frida 
Published: November 2019

Abstract
Purpose
The prevalence of hip and groin problems in professional male ice hockey is unknown and suspected to differ between playing positions. The purpose of this study was to explore potential differences in the seasonal prevalence of hip and groin problems between playing positions in male elite ice hockey players and to explore the relationship between symptom duration and hip and groin function at the beginning of the new season.

Methods
Male ice hockey players [n = 329 (92 goalkeepers, 93 defensemen, 144 forwards), Mean age (SD): 24 (5)] from the professional leagues in Sweden responded to an online survey. The survey assessed presence of hip and groin problems (time loss and non-time loss) and symptom duration (categorized into 0, 1–6, or > 6 weeks) in the previous season, and current self-reported hip and groin function (Copenhagen Hip and Groin Outcome Score).

Results
During the previous season, 175 players (53.2%) had experienced hip and groin problems. Non time loss problems were experienced by 158 (48%) and time loss problems were experienced by 97 (29.5%) players. No significant differences between playing positions were found. Self-reported function differed significantly between players with different symptom duration and more disability was reported among players with longer symptom duration (p ≤ 0.002).

Conclusion
Regardless of playing position, hip and groin problems were prevalent in male ice hockey players. Players with hip and groin problems during the previous season had significantly worse hip and groin function in the beginning of the new season, and longer symptom duration was associated with more disability.

Level of evidence
III
Quantification of Maillard reaction products in animal feed
Authors: Hofmann Thomas , Engling Anne Christin , Martens Siriwan , Steinhöfel Olaf , Henle Thomas 
Published: November 2019

AbstractIndividual Maillard reaction products (MRPs), namely furosine, which is formed from Amadori product of lysine during acid hydrolysis, as well as N-ε-(carboxymethyl)lysine (CML), pyrraline and the arginine derivative MG-H1 (methylglyoxal-derived hydroimidazolone 1) were quantified in 78 samples of animal feed, belonging to 17 different feed types. The concentrations of the MRPs were dependent on the heat treatment during processing. Within similar feed types, significant differences in concentrations could be observed. MRPs can be suitable indicators to evaluate the impact of technological processing on the nutritional quality of animal feed.
Why Z-drugs are used even if doctors and nurses feel unable to judge their benefits and risks—a hospital survey
Authors: Heinemann Stephanie , Brockmöller Jürgen , Hagmayer York , Himmel Wolfgang 
Published: November 2019

Abstract
Background
Many patients receive Z-drugs for hospital-associated sleep problems, in spite of well-known risks. The aim of this study was to learn more about the attractiveness of Z-drugs, seen from the doctors’ and nurses’ perspective.

Methods
Using a standardized questionnaire, doctors (63/116) and nurses (73/243) in a German general hospital were surveyed about the risks and benefits of Z-drugs, compared with benzodiazepines.

Result
“Reduced time to get to sleep” was perceived by doctors (51%) and nurses (53%) to be a strong benefit of Z-drugs; “confusion” and “falls” were perceived by ca. 10% of doctors and ca. 15% of nurses to be a frequent problem. Compared with benzodiazepines, respondents more often answered “unable to judge” for Z-drugs; e.g. for doctors, 18% (benzodiazepines) vs. 45% (Z-drugs) were unable to judge “improved daytime functioning” and 12% (benzodiazepines) vs. 37% (Z-drugs) were unable to judge “falls.”

Conclusion
Z-drugs seem to be attractive because experiential knowledge overemphasizes their benefits and fails to take risks such as drug-related falls and confusion into account. Difficulties to judge a drug’s risk-benefit ratio do not prevent doctors and nurses from using them. Interventions for reducing Z-drug usage should incorporate local quality assurance data about relevant patient risks.
Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study
Authors: Lazou Ahrén Irini , Berggren Anna , Teixeira Cristina , Martinsson Niskanen Titti , Larsson Niklas 
Published: November 2019

Abstract
Background
The combination of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 (commercially available as Probi Defendum®) has previously been reported to reduce the incidence, duration and severity of naturally acquired common colds in adults. The aim of the present study was to evaluate the impact of Probi Defendum® on aspects of common cold in healthy children 1–6 years of age attending day care.

Methods
A total of 131 children, out of the planned 320, were recruited into the study during 1 common cold season and randomised to consume once daily either 109 CFU (colony forming units) of the probiotic product or placebo. Due to unforeseen reasons, the recruitment of more children did not continue beyond the first cold season.

Results
There were 106 children that completed the study out of the 131 randomised. Daily consumption of the probiotic product for a period of 3 months significantly reduced the severity of the symptom “nasal congestion/runny nose” with a mean severity score for the whole study period of 7.5 ± 9.7 in the probiotic group and 13.9 ± 15.2 in the placebo (p < 0.05). Moreover, significantly less concomitant medication was used in the probiotic group. When the data were projected to a larger population corresponding to the originally estimated sample size, the results were in favour of the probiotic group regarding the reduced absence from day care (p < 0.05), reduced mean total severity per day in the reported episodes (p < 0.05) and reduced severity of the symptom “crying more than usual” (p < 0.05).

Conclusion
Intake of Probi Defendum® once daily for a period of 3 months was beneficial to children and reduced the severity of common colds.
Relationship between bullet diameter and bullet defect diameter in human calvariums
Authors: Kerkhoff W. , Mattijssen E. J. A. T. , Zwanenburg E. A. , Oostra R. J. 
Published: November 2019

AbstractExisting literature on the relationship between bullet diameter and bullet defect diameter in the human calvarium is summarized and discussed. The hypothesis, derived from the literature, that bullet deformation influences bullet defect diameter was studied in a small controlled experiment. The mean defect size caused by non-deforming projectiles was found to be smaller than the mean defect size caused by deforming projectiles of equal original mass and size. The p value of the difference between the two means, measured in two different ways, was found to be 0.002 for both in a Mann–Whitney U test and was significant if the confidence level is set at 5%.
Physiological functions of urea transporter B
Authors: Yu Lanying , Liu Tiantian , Fu Shuang , Li Li , Meng Xiaoping , Su Xin , Xie Zhanfeng , Ren Jiayan , Meng Yan , Lv Xuejiao , Du Yanwei 
Published: November 2019

AbstractUrea transporters (UTs) are membrane proteins in the urea transporter protein A (UT-A) and urea transporter protein B (UT-B) families. UT-B is mainly expressed in endothelial cell membrane of the renal medulla and in other tissues, including the brain, heart, pancreas, colon, bladder, bone marrow, and cochlea. UT-B is responsible for the maintenance of urea concentration, male reproductive function, blood pressure, bone metabolism, and brain astrocyte and cardiac functions. Its deficiency and dysfunction contribute to the pathogenesis of many diseases. Actually, UT-B deficiency increases the sensitivity of bladder epithelial cells to apoptosis triggers in mice and UT-B-null mice develop II-III atrioventricular block and depression. The expression of UT-B in the rumen of cow and sheep may participate in digestive function. However, there is no systemic review to discuss the UT-B functions. Here, we update research approaches to understanding the functions of UT-B.
Prevention of transmission of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum by Ixodes spp. ticks to dogs treated with the Seresto® collar (imidacloprid 10% + flumethrin 4.5%)
Authors: Krämer Friederike , Hüsken Ricarda , Krüdewagen Eva Maria , Deuster Katrin , Blagburn Byron , Straubinger Reinhard K. , Butler Jamie , Fingerle Volker , Charles Sam , Settje Terry , Schunack Bettina , Stanneck Dorothee 
Published: November 2019

AbstractThe capability of imidacloprid 10% + flumethrin 4.5% (Seresto®) collars to prevent transmission ofBorrelia burgdorferisensu lato (Bbsl) andAnaplasma phagocytophilum(Ap) by naturally infected ticks was evaluated in two studies with 44 dogs. In each study, one group served as non-treated control, whereas the other groups were treated with the Seresto® collar. All dogs were exposed to naturallyBbsl- andAp-infected hard ticks (Ixodes ricinus,Ixodes scapularis). In study 1, tick infestation was performed on study day (SD) 63 (2 months post-treatment [p.t.]); in study 2, it was performed on SD 32 (one month p.t.) respectively SD 219 (seven months p.t.). In situ tick counts were performed 2 days after infestation. Tick counts and removals followed 6 (study 1) or 5 days (study 2) later. Blood sampling was performed for the detection of specificBbsl andApantibodies and, in study 1, for the documentation ofApDNA by PCR. Skin biopsies were examined forBbsl by PCR and culture (only study 1). The efficacy againstIxodesspp. was 100% at all time points. In study 1, two of six non-treated dogs became infected withBbsl, and four of six tested positive forAp; none of the treated dogs tested positive forBbsl orAp. In study 2, ten of ten non-treated dogs became infected withBbsl andAp; none of the treated dogs tested positive forBbsl orAp; 100% acaricidal efficacy was shown in both studies. Transmission ofBbsl andApwas successfully blocked for up to 7 months.
Measuring vincristine-induced peripheral neuropathy in children with cancer: validation of the Dutch pediatric–modified Total Neuropathy Score
Authors: Schouten S. M. , van de Velde M. E. , Kaspers G. J. L. , Mokkink L. B. , van der Sluis I. M. , van den Bos C. , Hartman A. , Abbink F. C. H. , van den Berg M. H. 
Published: November 2019

Abstract
Purpose
The aims were to evaluate the construct validity and reliability of the Dutch version of the pediatric-modified Total Neuropathy Score (ped-mTNS) for assessing vincristine-induced peripheral neuropathy (VIPN) in Dutch pediatric oncology patients aged 5–18 years.

Methods
Construct validity (primary aim) of the ped-mTNS was determined by testing hypotheses about expected correlation between scores of the ped-mTNS (range: 0–32) and the Common Terminology Criteria for Adverse Events (CTCAE) (range: 0–18) for patients and healthy controls and by comparing patients and controls regarding their total ped-mTNS scores and the proportion of children identified with VIPN. Inter-rater and intra-rater reliability and measurement error (secondary aims) were assessed in a subgroup of study participants.

Results
Among the 112 children (56 patients and 56 age- and gender-matched healthy controls) evaluated, correlation between CTCAE and ped-mTNS scores was as expected (moderate (r = 0.60)). Moreover, as expected, patients had significantly higher ped-mTNS scores and more frequent symptoms of VIPN compared with controls (both p < .001). Reliability as measured within the intra-rater group (n = 10) (intra-class correlation coefficient (ICCagreement) = 0.64, standard error of measurement (SEMagreement) = 2.92, and smallest detectable change (SDCagreement) = 8.1) and within the inter-rater subgroup (n = 10) (ICCagreement = 0.63, SEMagreement = 3.7, and SDCagreement = 10.26) indicates insufficient reliability.

Conclusion
The Dutch version of the ped-mTNS appears to have good construct validity for assessing VIPN in a Dutch pediatric oncology population, whereas reliability appears to be insufficient and measurement error high. To improve standardization of VIPN assessment in children, future research aimed at evaluating and further optimizing the psychometric characteristics of the ped-mTNS is needed.
Revision surgery in thoracic disc herniation
Authors: Dützmann Stephan , Rose Roli , Rosenthal Daniel 
Published: November 2019

Abstract
Purpose
Surgical treatment failures or strategies for the reoperation of residual thoracic disc herniations are sparsely discussed. We investigated factors that led to incomplete disc removal and recommend reoperation strategies.

Methods
As a referral centre for thoracic disc disease, we reviewed retrospectively the clinical records and imaging studies before and after the treatment of patients who were sent to us for revision surgery for thoracic disc herniation from 2013 to 2018.

Results
A total of 456 patients were treated from 2013 to 2018 at our institution. Twenty-one patients had undergone previously thoracic discectomy at an outside facility and harboured residual, incompletely excised and symptomatic herniated thoracic discs. In 12 patients (57%), the initial symptoms that led to their primary operation were improved after the first surgery, but recurred after a mean of 2.8 years. In seven patients (33%) they remained stable, and in two cases they were worse. All patients were treated via all dorsal approaches. In all 21 cases, the initial excision was incomplete regarding medullar decompression. All of the discs were removed completely in a single revision procedure. After mean follow-up of 24 months (range 12–57 months), clinical neurological improvement was demonstrated in seven patients, while three patients suffered a worsening and 11 patients remained stable.

Conclusion
Our data suggest that pure dorsal decompression provides a short relief of the symptoms caused by spinal cord compression. Progressive myelopathy (probably due to mechanical and vascular deficits) and scar formation may cause worsening of symptoms.

Graphic abstract
These slides can be retrieved under Electronic Supplementary Material.
Value chain climate resilience and adaptive capacity in micro, small and medium agribusiness in Jamaica: a network approach
Authors: Canevari-Luzardo Laura M. 
Published: November 2019

AbstractIn advancing relational understandings of resilience and adaptive capacity, this paper explores how business networks influence value chain climate resilience and the ability of small businesses to adapt to climate change. The relationship between value chain network attributes (i.e. connectivity and an actor’s centrality) and indicators of value chain resilience (e.g. information sharing, flexibility and redundancy) is investigated through the analysis of qualitative data derived from field interviews and from the quantitative assessment of network metrics characterising information, financial and material flows of three agricultural value chains in Jamaica. The study illustrates how network analysis offers a systematic approach for understanding value chain resilience and the adaptive capacity of micro, small and medium enterprises (MSMEs), and supports strategy development in business value chains. The study concludes that mixed-methods networked approaches provide valid methods for exploring a relational understanding of climate resilience in value chains, opening up new research opportunities for scholars interested in private sector climate adaptation.
Selenium and mercury in the hair of raccoons (Procyon lotor) and European wildcats (Felis s. silvestris) from Germany and Luxembourg
Authors: Kosik-Bogacka Danuta , Osten-Sacken Natalia , Łanocha-Arendarczyk Natalia , Kot Karolina , Pilarczyk Bogumiła , Tomza-Marciniak Agnieszka , Podlasińska Joanna , Chmielarz Mateusz , Heddergott Mike , Frantz Alain C. , Steinbach Peter 
Published: November 2019

AbstractThis study examined the concentration of total mercury (THg) and selenium (Se), as well as the molar ratio of Se:THg in hair samples of terrestrial animals. THg and Se concentrations were measured from the hair of raccoons (Procyon lotor) and European wildcats (Felis s. silvestris) from Germany and Luxembourg. Median THg concentrations in hair from raccoons and wildcats were 0.369 and 0.273 mg kg−1dry weight (dw), respectively. Se concentrations were higher in the hair of raccoons than of wildcats (0.851 and 0.641 mg kg−1dw, respectively). Total mercury concentration in hair of raccoons from Luxembourg was almost 5× higher that found in hair of raccoons from Germany; however, Se concentration was similar. Thus, molar ratio of Se:THg was ~4× higher in the hair of raccoons from Germany than those from Luxembourg. Significant negative correlation was found between THg concentration and Se:THg molar ratio in both wildcats and raccoons.
Internalism, Externalism, and the KK Principle
Authors: Bird Alexander , Pettigrew Richard 
Published: November 2019

AbstractThis paper examines the relationship between the KK principle and the epistemological theses of externalism and internalism. In particular we examine arguments from Okasha (Analysis 73(1):80–86, 2013) and Greco (J Philos 111(4):169–197, 2014) which deny that we can derive the denial of the KK principle from externalism.
Pericentric inversion (Inv) 9 variant—reproductive risk factor or benign finding?
Authors: Merrion Katrina , Maisenbacher Melissa 
Published: November 2019

AbstractPurposeTo report the unbalanced chromosome rearrangement rate and overall aneuploidy rate in day 5/6 embryos from a series of patients who underwent in vitro fertilization (IVF) with preimplantation genetic testing for structural rearrangements (PGT-SR) for the pericentric inversion 9 variant, inv(9)(p11q13) or inv(9)(p12q13), with concurrent 24 chromosome preimplantation genetic testing for aneuploidy (PGT-A).MethodsThis was a retrospective cohort analysis. IVF cycles and embryo biopsies were performed by referring clinics. Fifty-two trophectoderm biopsy samples from seven couples were sent to a single lab for PGT-SR for an inversion 9 variant with concurrent 24 chromosome PGT-A using single-nucleotide polymorphism (SNP) microarrays with bioinformatics.ResultsThe unbalanced rearrangement rate for this embryo cohort was 0/52 (0.0%); mean maternal age per embryo was 33.3 years (range 21–39 years). The overall euploid rate was 61.5% and aneuploidy rate was 38.5%.ConclusionsChromosome 9 pericentric inversions did not result in unbalanced structural rearrangements in day 5/6 embryo samples, supporting that this population variant is not associated with increased reproductive risks.
Lessons learnt from a large-scale curriculum reform: The strategies to enhance development work and reduce reform-related stress
Authors: Tikkanen Lotta , Pyhältö Kirsi , Pietarinen Janne , Soini Tiina 
Published: November 2019

AbstractSustainable school development is suggested to result in both meaningful learning and enhanced well-being for those involved in the reform work. The aim of the study was to gain a better understanding of the relations between the strategies utilised in school development work, school impact of the reform and burdening in the context of curriculum reform in Finland. Altogether 550 district-level stakeholders responsible for curriculum reform at the local level responded to the survey. Structural equation modelling (SEM) was utilised to explore the interrelations between the reform implementation strategy, collective proactive strategies of well-being, as well as reform-related stress and the perceived school impact of the reform. The results showed that the top-down–bottom-up implementation strategy was related to the school impact of the reform and to the use of collective proactive strategies and reduced levels of stress. Collective proactive strategies also contributed to lower stress levels and enhanced school impact. The results indicate that the top-down–bottom-up implementation strategy provides an effective way to promote sustainable school reform in terms of enhancing the collective and cumulative learning and reducing burdening of those involved in the reform.
Clear-cuts are temporary habitats, not matrix, for endangered grassland burnet moths (Zygaena spp.)
Authors: Bergman Karl-Olof , Burman Joseph , Jonason Dennis , Larsson Mattias C. , Ryrholm Nils , Westerberg Lars , Milberg Per 
Published: November 2019

AbstractBurnet moths (Zygaenaspp.) are day-flying Lepidoptera considered indicative of species-rich grasslands. In the present study, our aim was to clarify whether clear-cuts are habitat, supporting habitat or matrix for three species ofZygaena. We did so by sampling these species with sex pheromones on 48 clear-cuts, varying in amount of host and nectar plants, in southern Sweden. To compare the efficiency of such sampling, we also conducted transect walks on these clearcuts. Overall, host-plants on clear-cuts best explained the abundance ofZygaenaspp. recorded, better than nectar-plants or connectivity with nearby grasslands. These results indicate that clear-cuts with an abundance of host plants are used as a fully functional habitat, and not a supporting habitat in the sense of only providing nectar. There is no support in these results for considering clear-cuts as an inert matrix. With about half the work-effort, pheromone traps recorded 100 times moreZygaenaspp. as transect walks. The poor correspondence between observations during transects walks and pheromone trap catches suggestZygaenaspp. being difficult to monitor by transect walks. In contrast to grasslands, clear-cuts are short-term in nature requiring repeated recolonization, indicating the importance of permanent grasslands. However, clear-cuts are important temporary insect habitats due to their great acreage, and suitable management can increase the time they remain a habitat.
Robotic Standard Development Life Cycle in Action
Authors: Olszewska Joanna Isabelle , Houghtaling Michael , Goncalves Paulo J. S. , Fabiano Nicola , Haidegger Tamas , Carbonera Joel Luis , Patterson William Remington , Ragavan S. Veera , Fiorini Sandro R. , Prestes Edson 
Published: November 2019

AbstractRobotics is a fast-growing field which requires the efficient development of adapted standards. Hence, in this paper, we propose a development methodology to support the robot standardization effort led by international, technical, and professional associations such as the Institute of Electrical and Electronics Engineers (IEEE). Our proposed standard development life cycle is a middle-out, iterative, collaborative, and incremental approach we have successfully applied to the development of the new IEEE Ontological Standard for Ethically Driven Robotics and Automation Systems (IEEE P7007 Standard).
Magnetism and Conductivity Along Structural Domain Walls of SrTiO3
Authors: Frenkel Yiftach , Xie Yanwu , Hwang Harold Y. , Kalisky Beena 
Published: November 2019

AbstractThe interface between the oxide insulators LaAlO3 and SrTiO3 (LAO/STO) hosts a two-dimensional electron gas. The combination of interfacial conductivity and superconductivity at ultra-low temperatures with the physical phenomena of the oxide parent materials has fueled extensive research in the field since its discovery in 2004. Scanning superconducting quantum interference device (SQUID) measurements have shown that structural domain walls, formed below 105 K, modulate the current flow at the interface and recently revealed weak magnetic signals along the same domain structure. Here we use scanning SQUID to investigate the temperature dependence of different electronic properties of the LAO/STO interface. We find correlation between magnetism and conductivity, which are both spatially modulated on the domain structure. This data suggests a possible relation between the populations of electrons participating in each order.