bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endoscopic Management of Chronic Subdural Hematoma
Authors: Yadav Yad Ram , Ratre Shailendra , Parihar Vijay , Bajaj Jitin , Sinha Mallika , Kumar Ambuj 
Published: March 2020

Abstract
Background Twist drill evacuation, burr hole aspiration, mini-craniotomy, and craniotomy are some of the surgical methods to remove chronic subdural hematoma (CSDH). Endoscopic treatment was also recently found to be useful.
Methods We conducted a prospective study of 72 hematomas in 68 patients. Computed tomography was performed in all cases. Endoscopic surgery was performed in all CSDH patients.
Surgical procedure A 4-cm skin incision was performed at the most curved part of skull with the CSDH. A mini-craniotomy or enlarged burr hole was made. The inner and outer table of the burr hole margin was drilled to provide a straight trajectory to the hematoma cavity. An endoscope supported by a telescope holder was used. A modified silicone brain retractor was used in five patients. A subgaleal drain was left in all patients for 3 to 5 days.
Results There were 42 male and 26 female patients. The age ranged from 45 to 79 years (average: 69 years). All patients had a history of head trauma. Preoperative average Glasgow Coma Scale Score was 14. The procedure was effective in hematoma evacuation and a good visualization of the whole cavity in all patients. The endoscopic technique helped in complete hematoma removal in organized/solid clot, septations, and bridging vessels in 17, 2, and 2 cases, respectively. Duration of surgery ranged from 35 to 80 minutes. One death occurred. There was no recurrence, infection, fresh bleed, or injury to the brain or membrane.
Conclusion The endoscopic technique is an effective alternative technique for treating CSDH. Although the study has limitations because of the small number of patients with a short follow-up, the study indicated that thick and vascular membranes, septations, and organized and solid clots can be removed effectively using this technique.
The glottal stop in Guaraní and Paraguayan Spanish
Authors: Gynan Shaw N. , López Almada Ernesto Luís 
Published: March 2020

Abstract
This study documents the use of [ʔ] in Paraguay, analyzing its distribution among four phonetic contexts: word-internal (Guaraní), phrase-initial (Guaraní and Spanish), synalepha (Guaraní and Spanish), and linking (Spanish). In each context, [ʔ]’s distribution is analyzed by following stress and vowel. Stress favors retention of word-internal [ʔ] in Guaraní, phrase-initial [ʔ] in Spanish and epenthetic [ʔ] in Guaraní, while it disfavors use of [ʔ] in Spanish synalepha. The vowels [e] and [i] suppress word-internal and prothetic [ʔ] in Guaraní, and Spanish synalepha with [ʔ], whereas [o] and [u] suppress Spanish prothesis and epenthesis of [ʔ] for synalepha. The results suggest that, in this study of fluent bilinguals, [ʔ] in Spanish is the result of convergence rather than second language transfer.
A classification of receptive bilinguals
Authors: Sherkina-Lieber Marina 
Published: March 2020

AbstractThe term ‘receptive bilingualism/multilingualism’ is used for diverse populations, all of which understand a language without producing speech in it, but differ in the way this receptive ability was achieved and in the linguistic knowledge underlying it. In previous studies, not enough attention is given to the differences between types of receptive bilinguals (RBs); however, a thorough analysis of all types is necessary to understand the nature of receptive bilingualism and, consequently, language comprehension and production in general.I propose a classification of RBs based on the presence and nature of an acquisition process that led to receptive abilities. In this classification, RBs who comprehend a language mutually intelligible with one they know are distinguished from RBs with acquired knowledge. Within the former, RBs with and without previous exposure are distinguished. Within acquired types, RBs who comprehend a heritage language are distinguished from RBs who comprehend a second/foreign language.
It’s all in the attitude
Authors: Hirsch Galia 
Published: March 2020

AbstractBuilding on various theoretical approaches to translation (Hickey 1998;Bassnett 2001), this article demonstrates the intersection between translation and parody (Aoyama and Wakabayashi 1999) by comparing two musical texts: Rachid Taha’s “Douce France” and Seu Jorge’s Portuguese trans­lation of David Bowie’s “Life on Mars?”. According toLinda Hutcheon’s (1985)view of parody as a form of repetition maintaining a critical distance, both texts are parodic. Each parody presents a very different attitude, which influences their ethos. Rachid Taha’s cover involves irony, which often marks parody (Hutcheon 1985), and thus a negative ethos: criticizing his new country for grievances against immigrants. Seu Jorge, however, pays tribute to the Bowie song he translates. These observations illustrate the close relationship between parody and translation.
Thermal conductivity measurements in nanosheets via bolometric effect
Authors: Çakıroğlu Onur , Mehmood Naveed , Çiçek Mert Miraç , Karluk Azimet Akber , Rasouli Hamid Reza , Durgun Engin , Kasırga T Serkan 
Published: March 2020

Abstract
Thermal conductivity measurement techniques for materials with nanoscale dimensions require fabrication of very complicated devices or their applicability is limited to a class of materials. Discovery of new methods with high thermal sensitivity are required for the widespread use of thermal conductivity measurements in characterizing materials’ properties. We propose and demonstrate a simple non-destructive method with superior thermal sensitivity to measure the in-plane thermal conductivity of nanosheets and nanowires using the bolometric effect. The method utilizes laser beam heating to create a temperature gradient, as small as a fraction of a Kelvin, over the suspended section of the nanomaterial with electrical contacts. Local temperature rise due to the laser irradiation alters the electrical resistance of the device, which can be measured precisely. This resistance change is then used to extract the temperature profile along the nanomaterial using thermal conductivity as a fitting parameter. We measured the thermal conductivity of V2O3 nanosheets to validate the applicability of the method and found an excellent agreement with the literature. Further, we measured the thermal conductivity of metallic 2H-TaS2 for the first time and performed ab initio calculations to support our measurements. Finally, we discussed the applicability of the method on semiconducting nanosheets and performed measurements on WS2 and MoS2 thin flakes.
The Pedicled Robertson Mammaplasty: Minimization of Complications in Obese Patients With Extreme Macromastia
Authors: Restifo Richard J 
Published: March 2020

Abstract

Background
Breast reduction for extreme macromastia in obese patients is a potentially high-risk endeavor. Free nipple grafting as well as a variety of pedicled techniques have been advocated for large reductions in obese patients, but the number of different approaches suggests that no single method is ideal. This paper suggests the Robertson Mammaplasty, an inferior pedicle technique characterized by a curvilinear skin extension onto the pedicle, as a potentially favorable approach to this clinical situation.

Objectives
The author sought to determine the safety of the Pedicled Robertson Mammaplasty for extreme macromastia in obese patients.

Methods
The records of a single surgeon’s practice over a 15-year period were retrospectively reviewed. Inclusion criteria were a Robertson Mammaplasty performed with a &gt;3000-g total resection and a patient weight at least 20% above ideal body weight. Records were reviewed for patient characteristics, operative times, and complications.

Results
The review yielded 34 bilateral reduction patients that met inclusion criteria. The mean resection weight was 1859.2 g per breast, the mean body mass index was 36.4 kg/m2, and the mean sternal notch-to-nipple distance was 41.4 cm. Mean operative time was 122 minutes. There were no cases of nipple necrosis and no major complications that required reoperation under general anesthesia. A total 26.4% of patients had minor complications that required either local wound care or small office procedures, and 4.4% received small revisions under local anesthesia.

Conclusions
The Pedicled Robertson Mammaplasty is a fast and safe operation that yields good aesthetic results and a relative minimum of complications in the high-risk group of obese patients with extreme macromastia.

Level of Evidence: 4
Multivariate one-sided testing in matched observational studies as an adversarial game
Authors: Cohen P L , Olson M A , Fogarty C B 
Published: March 2020

Summary
We present a multivariate one-sided sensitivity analysis for matched observational studies, appropriate when the researcher has specified that a given causal mechanism should manifest itself in effects on multiple outcome variables in a known direction. The test statistic can be thought of as the solution to an adversarial game, where the researcher determines the best linear combination of test statistics to combat nature’s presentation of the worst-case pattern of hidden bias. The corresponding optimization problem is convex, and can be solved efficiently even for reasonably sized observational studies. Asymptotically, the test statistic converges to a chi-bar-squared distribution under the null, a common distribution in order-restricted statistical inference. The test attains the largest possible design sensitivity over a class of coherent test statistics, and facilitates one-sided sensitivity analyses for individual outcome variables while maintaining familywise error control through its incorporation into closed testing procedures.
Paediatric aortic valve replacement using decellularized allografts
Authors: Horke Alexander , Bobylev Dmitry , Avsar Murat , Meyns Bart , Rega Filip , Hazekamp Mark , Huebler Michael , Schmiady Martin , Tzanavaros Ioannis , Cesnjevar Robert , Ciubotaru Anatol , Laufer Günther , Zimpfer Daniel , Jashari Ramadan , Boethig Dietmar , Cebotari Serghei , Beerbaum Philipp , Tudorache Igor , Haverich Axel , Sarikouch Samir 
Published: March 2020

Abstract

OBJECTIVES
Options for paediatric aortic valve replacement (AVR) are limited if valve repair is not feasible. Results of paediatric Ross procedures are inferior to adult Ross results, and mechanical AVR imposes constant anticoagulation with the inherent risks.

METHODS
The study design was a prospective, multicentre follow-up of all paediatric patients receiving decellularized aortic homografts (DAHs) for AVR in 8 European centres.

RESULTS
A total of 106 children (77 boys) were operated (mean age 10.1 ± 4.8 years, DAH diameter 20.5 ± 3.8 mm). A total of 60 (57%) had undergone previous surgical interventions: 34 with 1, 15 with 2 and 11 with ≥3. There was one early death in a 12-year-old girl, who underwent her fourth aortic valve operation, due to intracerebral haemorrhage on extracorporeal membrane oxygenation after coronary reimplantation problems following 3-sinus reconstruction 1 year earlier. One 2-year-old patient died due to sepsis 2 months postoperatively with no evidence for endocarditis. In addition, a single pacemaker implantation was necessary and a 2.5-year-old girl underwent successful HTx due to chronic myocardial failure despite an intact DAH. After a mean follow-up of 3.30 ± 2.45 years, primary efficacy end points mean peak gradient (18.1 ± 20.9 mmHg) and regurgitation (mean 0.61 ± 0.63, grade 0–3) were very good. Freedom from death/explantation/endocarditis/bleeding/stroke at 5 years was 97.8 ± 1.6/85.0 ± 7.4/100/100/100% respectively. Calculated expected adverse events were lower for DAH compared to cryopreserved homograft patients (mean age 8.9 years), lower than in Ross patients (9.4 years) and in the same range as mechanical AVR (12.8 years).

CONCLUSIONS
Even though the overall number of paediatric DAH patients and the follow-up time span are still limited, our data suggest that DAHs may present a promising additional option for paediatric AVR.
International Organizations and the Creation of Customary International Law
Authors: Daugirdas Kristina 
Published: March 2020

Abstract
This article argues that international organizations ‘as such’ can contribute directly to the creation of customary international law for three independent reasons. First, the states establishing an international organization may subjectively intend for that organization to be able to contribute to the creation of at least some kinds of customary international law. Second, that capacity may be an implied power of the organization. Third, that capacity may be a byproduct of other features or authorities of the international organization – specifically, the combination of international legal personality and the capacity to operate on the international plane. Affirming international organizations’ direct role in making customary international law will not dramatically change the content of customary international law or the processes by which rules of customary international law are ascertained. But recognizing that role is significant because it will reinforce other conclusions about how international organizations fit into the international legal system, including that customary international law binds international organizations. Such recognition may also shift the way lawyers within international organizations carry out their work by affecting the sources they consult when answering legal questions, the materials they make publicly available and the kinds of expertise that are understood to be necessary to discharge their responsibilities. Finally, affirming international organizations’ role in creating customary international law may make international organizations more willing to comply with those rules.
Quantifying the Autonomic Response to Stressors—One Way to Expand the Definition of “Stress” in Animals
Authors: Gaidica Matt , Dantzer Ben 
Published: March 2020

Abstract
Quantifying how whole organisms respond to challenges in the external and internal environment (“stressors”) is difficult. To date, physiological ecologists have mostly used measures of glucocorticoids (GCs) to assess the impact of stressors on animals. This is of course too simplistic as Hans Seyle himself characterized the response of organisms to “noxious stimuli” using multiple physiological responses. Possible solutions include increasing the number of biomarkers to more accurately characterize the “stress state” of animal or just measuring different biomarkers to more accurately characterize the degree of acute or chronic stressors an animal is experiencing. We focus on the latter and discuss how heart rate (HR) and heart rate variability (HRV) may be better predictors of the degree of activation of the sympathetic–adrenal–medullary system and complement or even replace measures of GCs as indicators of animal health, welfare, fitness, or their level of exposure to stressors. The miniaturization of biological sensor technology (“bio-sensors” or “bio-loggers”) presents an opportunity to reassess measures of stress state and develop new approaches. We describe some modern approaches to gathering these HR and HRV data in free-living animals with the aim that heart dynamics will be more integrated with measures of GCs as bio-markers of stress state and predictors of fitness in free-living animals.
Satellite cells and their regulation in livestock
Authors: Gonzalez Madison L , Busse Nicolas I , Waits Christy M , Johnson Sally E 
Published: March 2020

AbstractSatellite cells are the myogenic stem and progenitor population found in skeletal muscle. These cells typically reside in a quiescent state until called upon to support repair, regeneration, or muscle growth. The activities of satellite cells are orchestrated by systemic hormones, autocrine and paracrine growth factors, and the composition of the basal lamina of the muscle fiber. Several key intracellular signaling events are initiated in response to changes in the local environment causing exit from quiescence, proliferation, and differentiation. Signals emanating from Notch, wingless-type mouse mammary tumor virus integration site family members, and transforming growth factor-β proteins mediate the reversible exit from growth 0 phase while those initiated by members of the fibroblast growth factor and insulin-like growth factor families direct proliferation and differentiation. Many of these pathways impinge upon the myogenic regulatory factors (MRF), myogenic factor 5, myogenic differentiation factor D, myogenin and MRF4, and the lineage determinate, Paired box 7, to alter transcription and subsequent satellite cell decisions. In the recent past, insight into mouse transgenic models has led to a firm understanding of regulatory events that control satellite cell metabolism and myogenesis. Many of these niche-regulated functions offer subtle differences from their counterparts in livestock pointing to the existence of species-specific controls. The purpose of this review is to examine the mechanisms that mediate large animal satellite cell activity and their relationship to those present in rodents.
Assessment of Tobacco Exposure During Pregnancy by Meconium Analysis and Maternal Interview
Authors: López-Rabuñal Ángela , Lendoiro Elena , González-Colmenero Eva , Concheiro-Guisán Ana , Concheiro-Guisán Marta , Peñas-Silva Patricia , Macias-Cortiña Manuel , López-Rivadulla Manuel , Cruz Angelines , de-Castro-Ríos Ana 
Published: March 2020

AbstractSmoking during pregnancy can have serious obstetric and fetal complications. Therefore, it is essential to identify in utero exposure to tobacco, being meconium the matrix of choice for this purpose. Meconium (n = 565) was analyzed for nicotine, cotinine and hydroxycotinine by LC–MS-MS. Then, tobacco meconium results were compared with smoking habits during pregnancy and neonatal outcomes measures (birth weight, length, head circumference, gestational age and Apgar scores). Although meconium analysis increased identification of in-utero exposure to tobacco (17.7% meconium positive specimens vs 13.5% mothers admitting tobacco use during pregnancy), there was a statistically significant relationship between meconium results and interview answers (P &lt; 0.001). Birth weight was significantly lower for newborns with meconium positive results in males (P = 0.023) and females (P = 0.001), while for length significance was only observed in females (P = 0.001); however, when excluding meconium specimens positive for other drugs, a statistically significant difference was only found for female weight (P = 0.045). Meconium analysis proved to be more reliable for tobacco prenatal exposure detection than maternal interview. In addition, positive meconium results increased the probability for low birth weight, especially in females.
Development of Lucilia sericata (Diptera: Calliphoridae) Under Constant Temperatures and its Significance for the Estimation of Time of Death
Authors: Wang Man , Wang Yu , Hu Guoliang , Wang Yinghui , Xu Wang , Wu Maowang , Wang Jiangfeng 
Published: March 2020

Abstract
Forensic entomologists usually estimate the minimum postmortem interval (PMImin) using the time required for the oldest immature insects found on the corpse to grow to its development stage and age at the time of discovery. The sheep blow fly Lucilia sericata (Meigen, 1826) is a carrion fly found nearly worldwide, and important in forensics. We studied the development time of L. sericata from egg to adult at constant temperatures of 16, 19, 22, 25, 28, 31, and 34°C, and found that the times required are 913.2 ± 19.4, 588.8 ± 35.8, 459.8 ± 15.2, 373.2 ± 15.3, 308.0 ± 9.7, 272.5 ± 9.2, and 267.5 ± 10.5 h, respectively. We established three development models to infer the age of the immature insect: isomegalen diagram, isomorphen diagram, and thermal summation model. In addition, a regression analysis was performed on the relationship between body length and total development time from hatching to dispersing. The thermal summation constant during the development of L. sericata is 6023.2 degree hours and development threshold temperature is 9.19°C. The results of this experiment provide a basis for the use of L. sericata in the estimation of PMImin.
Curative resection of a duodenal gastrointestinal stromal tumor in the setting of von Willebrand’s disease
Authors: Litow Kyle , Jabbour Gaby , Bahn-Humphrey Alexandra , Stoller Christy , Rhee Peter , Latifi Rifat , Prabhakaran Kartik , Veillette Gregory 
Published: March 2020

Abstract
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the alimentary tract and usually presents with gastrointestinal hemorrhage. The diagnosis of GIST is typically made with upper endoscopy after excluding other causes of bleeding. The surgical management of GIST can be challenging depending upon the location of the tumor. We present a unique case of duodenal GIST in the setting von Willebrand’s disease diagnosed after emergent laparotomy for massive gastrointestinal hemorrhage. Key strategies in curing our patient were treating the underlying bleeding disorder, collaborating with radiology and gastroenterology teams, and early exploratory laparotomy for refractory hemorrhage. This case demonstrates the challenges of diagnosing and managing GIST in patients with underlying coagulopathies.
Chest Pain From Supplement Use in an Active Duty Soldier: A Case Report
Authors: Bridwell Rachel E , Yoo Michael J , Grove Jordan J , Ng Patrick C 
Published: March 2020

Abstract
In the active duty population, over-the-counter performance enhancing supplements are readily available and consumed, primarily in an unsupervised manner. While some of the active ingredients, such as caffeine and creatine, have been well studied, other sympathomimetic and vasoactive components in these products have minimal data regarding their safety profile. Further potentiating the associated risks of consumption, the quantities and purities of the reported ingredients are often unverified and can vary from serving to serving. We present a case of the deleterious side effect profiles of these lesser studied components in overconsumption in an active duty soldier. Although improvements are being made regarding product safety, the paucity of ingredient regulation and quality assurance can result in warfighter morbidity and mortality, especially when these supplements are abused or combined with other products.