bluuebunny/crossref_metadata_2025_split huggingface dataset:
مدى استخدام المختبرات في تدريس الكيمياء في المدارس الثانوية في محافظة الضالع من وجهة نظر المعلمين والمعلمات
Authors: عبيد صالح قاسم علي 
Published: December 2024

هدفت الدراسة إلى معرفة مدى استخدام المعامل في تدريس الكيمياء بالمدارس الثانوية بمحافظة الضالع من وجهة نظر المعلمين والمعلمات. واستخدم الباحث المنهج الوصفي التحليلي، واشتمل مجتمع الدراسة على معلمي الكيمياء بجميع المدارس الثانوية بمحافظة الضالع، والذين بلغ عددهم (110) معلماً ومعلمة. وقد اعتبر الباحث عينة الدراسة هم عدد المعلمين والمعلمات الذين استجابوا للاستبيان وعددهم (63) بنسبة (60%). ومن خلال هذه الدراسة توصل الباحث إلى عدد من النتائج أهمها: - عدم توفر المعامل العلمية في العديد من المدارس الثانوية بمحافظة الضالع حيث بلغت نسبة عدم توفرها (60.3%) حيث وجدت القناعة التامة لدى المعلمين بأهمية استخدام المختبرات العلمية في التدريس . وأوصت الدراسة بضرورة تحديث المدارس بالمختبرات العلمية وتزويدها بالمواد والأدوات والأجهزة اللازمة لاستخدامها في التدريس .
An Epidemiological Analysis of Leishmaniasis in Dhamar Governorate (2011–2013), Northern of Yemen
Authors: Al-Koleeby Zalalham Al-Koleeby 
Published: December 2024

Over the past few years,Dhamar Governorate in North Yemen has seen an increase in leishmaniasis cases.The current study aims to assess the epidemiological profile, namely the spatiotemporal tracking of all leishmaniasis cases,and provides an epidemiological overview of the local population.This review focuses on leishmaniasis cases that were documented from 2011 to 2013. To analyze the data, Excele software (version 20) was utilized.There were 759 instances of leishmaniasis over a three-year period, from 2011 to 2013, with 94.99% of cases being cutaneous and 5.01% being mucocutaneous. There are between 0.97564276 and 0.05818674 cases of leishmaniasis in the Governorate of Dhamar. For every type of leishmaniasis, the male sex was more affected than the female sex.Cutaneous leishmaniasis had a major effect on all age groups: patients aged 0–10 made up 54.94% of cases, while those aged 11–20 made up 28.15%.Mucocutaneous leishmaniasis has primarily affected aged [0–10] with 86.84% of cases.Geographically,the Anss region recorded the highest number of leishmaniasis cases (107 cases), followed by Maghrib Ans (29 cases) and Utmah (53 cases).Thus, leishmaniasis is a major health risk in Dhamar Governorate. To stop the disease's spread, all concerned parties must move fast to set up a regional control program. and additional research on the dynamics and ecology of sandfly vectors.
CLINICAL CASE: GOTTRON'S PROGRESSIVE ERYTHROKERATODERMA
Authors: Jumanova А.E. , Ospanova C.A. , Sukhanberdiyeva Z.M. 
Published: December 2024

The article describes a case of Gottron's erythrokeratoderma, which is characterized by a predominantly autosomal dominant type of inheritance and refers to keratinization disorders with increased epidermal cell proliferation. A rare clinical case of autosomal recessive progressive symmetrical Gottron's erythrokeratoderma is described, characterized by seasonal changes in the skin pathological process - the appearance of rashes in winter and complete remissions in summer.
Мақалада негізінен аутосомды-доминантты тұқым қуалаушылық түрімен сипатталатын және эпидермис жасушаларының пролиферациясының жоғарылауымен корнификациялық бұзылыстармен байланысты Готтрон эритрокератодермасының жағдайы сипатталған. Терінің патологиялық процесінің маусымдық өзгерістерімен сипатталатын Готронның аутосомды-рецессивті прогрессивті симметриялық эритрокератодермиясының сирек клиникалық жағдайы сипатталған - қыста бөртпелердің пайда болуы және жазда толық ремиссия.
SYSTEMATIC LITERATURE REVIEW HUBUNGAN KONSUMSI NATRIUM DENGAN KEJADIAN HIPERTENSI PADA REMAJA
Authors: Delfilaura Asyifa , Amelin Fitrisia , Machmud Rizanda 
Published: December 2024

Background : Hypertension does not only occur in adults but also in adolescents, it will be very risky to develop into serious early disease. One of the risk factors for hypertension is the habit of consuming high amounts of sodium, especially in adult hypertension. However, the relationship between sodium intake and the incidence of hypertension in children and adolescents is still controversial and the literature review studies found are still few. Objective : This research aim to assess the relationship between sodium intake with hypertension in adolescents based on literature review. Methods : This research is a systematic literature review. A literature search was conducted on the Pubmed and Google Scholar databases using inclusion and exclusion criteria. The data synthesis in this literature review was carried out quantitatively. Results : A total of 8 studies were included in the systematic which 4 studies from them is carried out a meta-analysis. The average adolescent consumes sodium above the requirement ranging from 1503 mg per day to 4000 mg per day. The average prevalence of hypertension in adolescents is 2.2% - 35.8%. From the results of the meta-analysis, it was found that there was a significant relationship between sodium consumption and the incidence of hypertension in adolescents with a value of P = 0.00001 (P <0.05). Conclusion : Most adolescents consume sodium above the nutritional recommendation. The prevalence of adolescent hypertension continues to increase. There is a significant relationship between sodium intake and hypertension in adolescents.
COMUNIDADES DE PRÁTICA E LETRAMENTOS DE REEXISTÊNCIA EM UMA ESCOLA DE SAMBA DO RIO DE JANEIRO
Authors: Martins Danielle da Silva , Oliveira Marcia Lisbôa Costa de 
Published: December 2024

O estudo discute letramentos de reexistência construídos no carnaval do G.R.E.S Unidos do Viradouro (RJ), buscando compreender como sentidos multimodais, inclusive em meios digitais, são negociados nessa comunidade de prática. Adotou-se abordagem qualitativa, desenvolvendo-se observação participante, análise de textos e documentos. Nas escolas de samba, o maior empreendimento comum é o desfile oficial, sendo o engajamento mútuo vivenciado em eventos sociais e atividades relacionadas ao carnaval, situações em que se constitui um repertório compartilhado. A análise realizada indica que os letramentos de reexistência construídos na Viradouro são multimodais e indissociáveis da valorização das culturas afrodiaspóricas, ancorando-se no pertencimento à comunidade.
Characterization and clinical outcomes of outpatients with subacute or chronic post COVID-19 cough: a real-world study
Authors: Yao Chun , Cheng Dongliang , Yang Wenhong , Guo Yun , Zhou Tong 
Published: December 2024

Background
Limited research exists on the features and management of post-COVID cough. This real-world study investigates outpatients with subacute or chronic post-COVID cough, aiming to delineate characteristics and regimen responses within the population.

Method
We enrolled eligible patients from our outpatient unit between August 2023 and February 2024. Comprehensive clinical data, prescriptions, and patient-reported cough severity were collected during the primary visit and subsequent follow-ups.

Result
A total of 141 patients, aged: 42 ± 14 years old, were included, with 70% being female. The median cough duration was 8 weeks (interquartile range 4–12 weeks). Sixty percent presented with a dry cough, while the rest had coughs with phlegm. Over half reported abnormal laryngeal sensations (54%). Twenty-one percent coughed during the day, while 32% coughed constantly, and 48% experienced nocturnal episodes. Compound methoxyphenamine capsules were the most prescribed, but our study found ICS/LABA to be the most effective, followed by compound methoxyphenamine capsules, montelukast, and Chinese patent drugs.

Conclusion
Females exhibit a higher prevalence of post-COVID cough, and our study recommends ICS/LABA as the preferred treatment. These findings warrant validation through larger, prospectively designed studies.
Flexible Pressure Sensors for Objective Assessment of Motor Disorders
Authors: Amit Moran , Chukoskie Leanne , Skalsky Andrew J. , Garudadri Harinath , Ng Tse Nga 
Published: November 2019

AbstractMonitoring body motion is relevant to motor control disorders as well as assessment of fine motor skills in child development. Furthermore, motion tracking is necessary for rehabilitation monitoring and injury prevention and benefits both sick and healthy individuals. Flexible pressure sensors based on resistors, capacitors, inductors, or transistors are reviewed in the context of healthcare measurements, ranging from physiological signals to body movement characteristics such as grip and gait. To demonstrate the use of flexible pressure sensors for motor assessment, a touch sensing glove that evaluates fine motor skills in autism research is developed. The results show that autistic children perform fewer taps per minute compared to typically developing children, with larger variations in tap durations. In a second example, a force and motion sensing glove is developed to assess spasticity, a neuromuscular disorder that causes muscle stiffness/resistance and jerky movement. Analyses of force versus velocity show movement‐dependent muscle resistance in a patient with spasticity. Through these flexible sensor systems, the shift from subjective scores to objective measurement will promote better diagnosis and dramatically improve the accuracy in tracking patient response to therapy.
Bisphosphonate‐Functionalized Scaffolds for Enhanced Bone Regeneration
Authors: Cui Yutao , Zhu Tongtong , Li Di , Li Zuhao , Leng Yi , Ji Xuan , Liu He , Wu Dankai , Ding Jianxun 
Published: November 2019

AbstractThe local sustained release of bioactive substances are attracting increasing attention in bone tissue engineering, which is beneficial to bone tissue formation and helps to improve the bone ingrowth ability of a scaffold. Bisphosphonates (BPs), as a representative kind of osteoclast inhibitors, are proven to possess excellent osteogenic induction capability. Accordingly, various physical and chemical strategies are developed to functionalize bone tissue scaffolds with BPs to achieve controlled release profiles. Compared with traditional treatment modalities, local release of BPs from these composite scaffolds will contribute to continuous bone integration without the risk of many complications. This review explores the molecular mechanisms of BPs on bone metabolism and analyzes the appropriate concentrations of BPs that promote bone regeneration. The advanced BP loading strategies, implant modification technologies, and BP‐loaded composite scaffolds based on different matrices are summarized. Finally, the latest advances and the future development of BP‐modified scaffolds for enhanced bone regeneration are discussed. This article provides leading‐edge design strategies of the BP‐functionalized bone engineering scaffolds for improved bone repairability.
Terahertz Emission Functionality of High‐Temperature Superconductors and Similar Complex Systems
Authors: Rana Dhanvir Singh , Tonouchi Masayoshi 
Published: November 2019

AbstractDuring the past two decades, terahertz (THz) science and technology have rapidly expanded in all fundamental and applied aspects of physical, chemical, and biological sciences. In physical sciences, these developments have been twofolds: i) the use of THz technology in understanding the complexities of materials and ii) the exploration of new THz functionalities of emerging materials for further advancement of THz technology. Here, the THz emission spectroscopy and the ultrafast functionality of three pillars of electronic and magnetic condensed matter systems that emerged in the following order: high‐temperature superconductors, colossal magnetoresistive manganites, and magnetoelectric multiferroics are reviewed. Emission functionality refers to the emitted THz radiation that carries the information of the underlying functional property of the material such that the overall effect evolves as the THz decoding of the information in a noninvasive manner and on an ultrafast timescale.
Revealing the Intrinsic Electronic Structure of 3D Half‐Heusler Thermoelectric Materials by Angle‐Resolved Photoemission Spectroscopy
Authors: Fu Chenguang , Yao Mengyu , Chen Xi , Maulana Lucky Zaehir , Li Xin , Yang Jiong , Imasato Kazuki , Zhu Fengfeng , Li Guowei , Auffermann Gudrun , Burkhardt Ulrich , Schnelle Walter , Zhou Jianshi , Zhu Tiejun , Zhao Xinbing , Shi Ming , Dressel Martin , Pronin Artem V. , Snyder G. Jeffrey , Felser Claudia 
Published: November 2019

AbstractAccurate determination of the intrinsic electronic structure of thermoelectric materials is a prerequisite for utilizing an electronic band engineering strategy to improve their thermoelectric performance. Herein, with high‐resolution angle‐resolved photoemission spectroscopy (ARPES), the intrinsic electronic structure of the 3D half‐Heusler thermoelectric material ZrNiSn is revealed. An unexpectedly large intrinsic bandgap is directly observed by ARPES and is further confirmed by electrical and optical measurements and first‐principles calculations. Moreover, a large anisotropic conduction band with an anisotropic factor of 6 is identified by ARPES and attributed to be one of the most important reasons leading to the high thermoelectric performance of ZrNiSn. These successful findings rely on the grown high‐quality single crystals, which have fewer Ni interstitial defects and negligible in‐gap states on the electronic structure. This work demonstrates a realistic paradigm to investigate the electronic structure of 3D solid materials by using ARPES and provides new insights into the intrinsic electronic structure of the half‐Heusler system benefiting further optimization of thermoelectric performance.
Tailoring electronic properties and kinetics behaviors of Pd/N‐CNTs catalysts for selective hydrogenation of acetylene
Authors: Cao Yueqiang , Fu Wenzhao , Ren Zhouhong , Sui Zhijun , Zhou Jinghong , Luo Jun , Duan Xuezhi , Zhou Xinggui 
Published: November 2019

AbstractPd catalyzed selective hydrogenation of acetylene shows remarkable electronic effects. In this work, a strategy is proposed to tailor the electronic properties of Pd nanoparticles by nitrogen doping of carbon nanotubes (CNT) support toward the improved reaction kinetics. While excluding the Pd size effects, the intrinsic promotional effects of the nitrogen doping are demonstrated, which are mainly due to the increased Pd electron density resultant from the presence of more graphitic nitrogen species based on X‐ray photoelectron spectroscopy measurements and density functional theory (DFT) calculations. Kinetics analysis and C2H2/C2H4‐temperature‐programmed desorption (TPD) measurements reveal that the electron‐rich Pd catalyst with the moderately weakened adsorption strength can give rise to the decreased activation energy and thus the simultaneously enhanced activity, selectivity, and stability. The aspects demonstrated here could guide the rational design and optimization of Pd catalysts for the selective hydrogenation of acetylene.
Efficient adsorptive separation of propene over propane through a pillar‐layer cobalt‐based metal–organic framework
Authors: Wu Houxiao , Yuan Yinuo , Chen Yongwei , Xu Feng , Lv Daofei , Wu Ying , Li Zhong , Xia Qibin 
Published: November 2019

AbstractThe purification of propene from the propene/propane binary mixture is one of the most important and challenging separation processes in the chemical industry. In this study, a cobalt‐based pillar‐layer metal–organic framework, Co(AIP)(BPY)0.5, was synthesized. It exhibited excellent water and moisture stability and efficient C3H6/C3H8 separation performance. At 298 K and 100 kPa, the adsorption capacity of C3H6 was 1.99 mmol/g and the IAST adsorption selectivity was 21, which has exceeded most investigated MOFs adsorbents. The cyclic breakthrough experiments of C3H6/C3H8 binary mixture confirmed its efficient dynamic separation property and excellent recyclability. The molecular simulation showed that the C3H8 molecules with multiple binding sites (C─H) were restricted at the middle of the one‐dimensional channel. Compared with C3H6, the large steric hindrance of C3H8 caused lower diffusion rate (with a C3H6/C3H8 kinetic selectivity of 29.7, at 303 K) in the narrow pore system of 1, which has been confirmed by the kinetic adsorption experiments.
Clinical outcomes of multiple myeloma patients who undergo autologous hematopoietic stem cell transplant with G‐CSF or G‐CSF and plerixafor mobilized grafts
Authors: Shah Harsh , Kim Seongho , Singh Paramveer , Alavi Asif , Ratanatharathorn Voravit , Ayash Lois , Uberti Joseph , Deol Abhinav 
Published: November 2019

AbstractImpact of Plerixafor (P) mobilized stem cells on immune reconstitution, such as absolute lymphocyte count at day 30 (ALC30), and on long‐term outcomes of Multiple Myeloma (MM) patients undergoing autologous stem cell transplant (ASCT) has not been well established. We evaluated total of 469 patients mobilized with G‐CSF (G) alone, and 141 patients mobilized with G‐CSF plus plerixafor (G+ P). Patients only received plerixafor if they had peripheral blood CD34+  blood count <20/μL on first planned day of collection. Primary endpoint, ALC30, was 1.3 K/μL (range, 0.1‐4.5) and 1.2 K/μL (range, 0.1‐5.1) for G and G + P, respectively (P =. 61). The median PFS was 2.5 years (95% CI, 2.1‐3.2) and 2.8 years (95% CI, 2.0‐3.3) for G and G + P, respectively (HR: 1.13; 95% CI, 0.84‐1.50; P = .42). The median OS was 6.1 years (95% CI, 4.6‐NR) for G group compared to 3.7 years (95% CI, 3.2‐NR) for the G + P group (HR: 1.64; 95% CI, 1.12‐2.40; P = .01). The median follow‐up time for OS was 2.53 years (95% CI, 2.13‐2.99) and 1.59 years (95% CI, 1.17‐2.02) for G and G+ P group, respectively. In this large retrospective analysis of MM patients mobilized with G‐CSF vs G‐CSF + P, there was no significant difference in lymphocyte recovery or PFS. There was an overall survival difference in patients who were poor mobilizers and could not be mobilized with G‐CSF alone.
Myokine levels after resistance exercise in young adults with Prader–Willi syndrome (PWS)
Authors: Hirsch Harry J. , Gross‐Tsur Varda , Sabag Yanir , Nice Shachar , Genstil Larry , Benarroch Fortu , Constantini Naama 
Published: November 2019

AbstractIndividuals with PWS require marked caloric restriction and daily exercise to prevent morbid obesity. Lower energy expenditure, hypotonia, decreased muscle mass, and cognitive impairment make exercise challenging for this population. Exercise guidelines include resistance training as an important component. Myokine responses to resistance exercise may mediate beneficial metabolic effects. We aimed to determine if young PWS adults can perform a resistance exercise program and to measure myokine responses in PWS versus age‐ and BMI‐matched controls. Each group included 11 participants (7M/4F). Ages and BMI for PWS and controls were 30.7 ± 4.6 versus 30.1 ± 4.3 years and 28.3 ± 4.3 versus 28.2 ± 4.2 kg/m2, respectively. Glucose, creatine kinase (CK), lactate, and myokines were measured before, after, 30, and 60 min after completing eight resistance exercises. Myokines were assayed using a multiplex myokine panel (Merck Millipore). CK was lower in PWS versus controls (62 ± 16 vs.322 ± 100 U/L, p < .04). Peak lactate was 3.7 ± 0.7 in PWS versus 7.3 ± 0.7 mmol/Lin controls (p < .001). The increase in interleukin‐6 was similar in PWS and controls (41 ± 16% and 35 ± 10%, respectively). Pre‐ and post‐exercise levels of the six myokines assayed showed no consistent differences between the PWS and control participants. PWS young adults are capable of performing resistance/strength‐building exercise. The lower CK and peak lactate levels in PWS may reflect decreased muscle mass in this population. Further studies are needed to determine optimal exercise regimens and assess the role of myokines incontributing to the metabolic phenotype of PWS.
Cigarette smoke extract inhibits cell migration and contraction via the reactive oxygen species/adenosine monophosphate–activated protein kinase pathway in nasal fibroblasts
Authors: Shin Jae‐Min , Park Joo‐Hoo , Yang Hyun‐Woo , Lee Heung‐Man , Park Il‐Ho 
Published: November 2019

BackgroundFibroblast migration plays a significant role in wound healing after endoscopic sinonasal surgery. Cigarette smoke extract (CSE) is a potent inhibitor of fibroblast functions including cell proliferation and migration. The purpose of the study was to determine the influence of CSE on migration and collagen gel contraction in nasal fibroblasts and investigate its underlying mechanisms.MethodsFibroblast migration was evaluated using wound healing assay and transwell migration assay. Contractile activity was assessed by collagen gel contraction assay. Reactive oxygen species (ROS) were quantified by 2′,7′‐dichlorofluorescein diacetate. Fibroblasts were treated with CSE and N‐acetylcysteine (NAC), metformin, compound C, or transfected with small interfering RNA (siRNA) to suppress adenosine monophosphate–activated protein kinase (AMPK) expression. AMPK activation was determined by Western blot.ResultsCSE and metformin were found to significantly reduce the migration and collagen gel contraction activity of nasal fibroblasts. Conversely, pretreatment with NAC and compound C significantly enhanced the migration and collagen gel contraction activity of fibroblasts. ROS production and AMPK phosphorylation were found to be significantly induced by CSE treatment, whereas the activity was inhibited on treatment with NAC, metformin, compound C, or AMPK siRNA. Silencing of AMPK expression was found to significantly reverse the suppressive effect of CSE in nasal fibroblasts.ConclusionCSE has an inhibitory effect on cell migration and collagen gel contraction activity via the ROS/AMPK signaling pathway in nasal fibroblasts.
Efficacy of protocol‐based non‐invasive positive pressure ventilation for acute respiratory distress syndrome: a retrospective observational study
Authors: Satou Takahisa , Imamura Hiroshi , Mochiduki Katunori , Ichikawa Michitaro , Takeshige Kanako , Kamijo Hiroshi , Takayama Hiroshi , Nitta Kenichi , Kikuchi Tadashi , Okamoto Kazufumi 
Published: November 2019

AimThe efficacy of non‐invasive positive pressure ventilation (NPPV) in acute respiratory distress syndrome (ARDS) remains unclear. Variation in both the etiology of ARDS and patient factors has resulted in inconsistent application of NPPV. We have developed a protocol‐based NPPV strategy as a first‐line intervention for ARDS. The aim of this observational study was to determine if protocol‐based NPPV improves the outcome in patients with ARDS.MethodsWe identified patients with ARDS treated by protocol‐based NPPV at our institution between March 2006 and March 2010 and categorized them according to NPPV success or failure. Success was defined as avoidance of intubation and remaining alive during NPPV.ResultsEighty‐eight of 169 patients diagnosed with ARDS during the study period were treated using the protocol. Fifty‐two (76%) of 68 patients who were eligible for the study were successfully treated and did not require endotracheal intubation. The overall mortality rate at 28 days after initiation of NPPV was 12%. The mortality rate was significantly lower in the success group than in the failure group (P < 0.01). The PaO2/FiO2 ratio after 12–24 h of NPPV was significantly higher in the success group than in the failure group (202 ± 63 versus 145 ± 46; P < 0.01).ConclusionsThe success rate was higher and the mortality was lower in patients than in historical controls. Protocol‐based NPPV could be effective in patients with ARDS.