bluuebunny/crossref_metadata_2025_split huggingface dataset:
A joint inversion of receiver function and Rayleigh wave phase velocity dispersion data to estimate crustal structure in West Antarctica
Authors: Dunham C K , O’Donnell J P , Stuart G W , Brisbourne A M , Rost S , Jordan T A , Nyblade A A , Wiens D A , Aster R C 
Published: August 2020

SUMMARY
We determine crustal shear wave velocity structure and crustal thickness at recently deployed seismic stations across West Antarctica, using a joint inversion of receiver functions and fundamental mode Rayleigh wave phase velocity dispersion. The stations are from both the UK Antarctic Network (UKANET) and Polar Earth Observing Network/Antarctic Network (POLENET/ANET). The former include, for the first time, four stations along the spine of the Antarctic Peninsula, three in the Ellsworth Land and five stations in the vicinity of the Pine Island Rift. Within the West Antarctic Rift System (WARS) we model a crustal thickness range of 18–28 km, and show that the thinnest crust (∼18 km) is in the vicinity of the Byrd Subglacial Basin and Bentley Subglacial Trench. In these regions we also find the highest ratio of fast (Vs = 4.0–4.3 km s–1, likely mafic) lower crust to felsic/intermediate upper crust. The thickest mafic lower crust we model is in Ellsworth Land, a critical area for constraining the eastern limits of the WARS. Although we find thinner crust in this region (∼30 km) than in the neighbouring Antarctic Peninsula and Haag-Ellsworth Whitmore block (HEW), the Ellsworth Land crust has not undergone as much extension as the central WARS. This suggests that the WARS does not link with the Weddell Sea Rift System through Ellsworth Land, and instead has progressed during its formation towards the Bellingshausen and Amundsen Sea Embayments. We also find that the thin WARS crust extends towards the Pine Island Rift, suggesting that the boundary between the WARS and the Thurston Island block lies in this region, ∼200 km north of its previously accepted position. The thickest crust (38–40 km) we model in this study is in the Ellsworth Mountain section of the HEW block. We find thinner crust (30–33 km) in the Whitmore Mountains and Haag Nunatak sectors of the HEW, consistent with the composite nature of the block. In the Antarctic Peninsula we find a crustal thickness range of 30–38 km and a likely dominantly felsic/intermediate crustal composition. By forward modelling high frequency receiver functions we also assess if any thick, low velocity subglacial sediment accumulations are present, and find a 0.1–0.8-km-thick layer at 10 stations within the WARS, Thurston Island and Ellsworth Land. We suggest that these units of subglacial sediment could provide a source region for the soft basal till layers found beneath numerous outlet glaciers, and may act to accelerate ice flow.
Soy and isoflavone consumption and subsequent risk of prostate cancer mortality: the Japan Public Health Center-based Prospective Study
Authors: Sawada Norie , Iwasaki Motoki , Yamaji Taiki , Shimazu Taichi , Inoue Manami , Tsugane Shoichiro ,   for the Japan Public Health Center-based Prospective Study Group
Published: August 2020

AbstractBackgroundAlthough many epidemiological studies have reported the preventive effects of soy products and isoflavones on prostate cancer, our previous studies reported that the association between soy and isoflavones and prostate cancer incidence differed according to stage. It is more important to identify modifiable risk factors related to lethal prostate cancer. Here, we investigated the association between soy, soy products and isoflavones intake and prostate cancer mortality, in a prospective study in Japan.MethodsWe conducted a population-based prospective study in 43 580 Japanese men with no history of cancer or cardiovascular disease (aged 45-74 years). Participants completed a validated questionnaire which included 138 food items. We followed participants from 1995 to 2016. Hazard ratios (HRs) and 95% confidence intervals (CIs) of prostate cancer mortality were calculated according to quintiles of soy products and isoflavones intake, using Cox hazard proportional hazards regression.ResultsDuring 16.9 years follow-up, we registered 221 deaths from prostate cancer. Isoflavones and soy products intake was associated with an increased risk of prostate cancer death, with multivariate HRQ5 vs. Q1=1.39, 95% CI = 0.87-2.20, p for trend = 0.04 for isoflavones and multivariate HRQ5 vs. Q1=1.76, 95% CI = 1.10-2.82, p for trend = 0.04 for soy food.ConclusionsOur study suggested that high intake of soy and isoflavones might increase the risk of prostate cancer mortality.
Hib Vaccines: Their Impact on Haemophilus influenzae Type b Disease
Authors: Gilsdorf Janet R 
Published: August 2020

Abstract
Haemophilus influenzae serotype b (Hib) is an important cause of serious, invasive infections, particularly in young children. Since 1985, a series of vaccines composed of the type b capsular polysaccharide polyribosylribitol phosphate (PRP), followed by PRP conjugated to various proteins, have been licensed for use in the United States and worldwide. The conjugated vaccines offer increased immunogenicity and prolonged durability of immune protection compared to the plain PRP vaccine and increasingly are combined with other childhood vaccines for decreased cost and increased ease of vaccination. Hib vaccines have a very favorable safety profile, have been found to be either cost-saving or cost-effective by many public health agencies, and, in most countries, are initiated during early infancy as part of routine childhood immunization programs. As a result of widespread use of the vaccines, the incidence of Hib infections, and their associated morbidity and mortality, has fallen dramatically across the globe. Yet, many children remain unimmunized or underimmunized against Hib, particularly in limited-resource countries. Future efforts to further reduce the disease burden of Hib infections remain a high priority.
Native Human Antibody to Shr Promotes Mice Survival After Intraperitoneal Challenge With Invasive Group A Streptococcus
Authors: Chatterjee Nilanjana , Huang Ya-Shu , Lyles Kristin V , Morgan Julie E , Kauvar Lawrence M , Greer Susanna F , Eichenbaum Zehava 
Published: August 2020

Abstract

Background
A vaccine against group A Streptococcus (GAS) has been actively pursued for decades. The surface receptor Shr is vital in GAS heme uptake and provides an effective target for active and passive immunization. Here, we isolated human monoclonal antibodies (mAbs) against Shr and evaluated their efficacy and mechanism.

Methods
We used a single B-lymphocyte screen to discover the mAbs TRL186 and TRL96. Interactions of the mAbs with whole cells, proteins, and peptides were investigated. Growth assays and cultured phagocytes were used to study the mAbs’ impact on heme uptake and bacterial killing. Efficacy was tested in prophylactic and therapeutic vaccination using intraperitoneal mAb administration and GAS challenge

Results
Both TRL186 and TRL96 interact with whole GAS cells, recognizing the NTR and NEAT1 domains of Shr, respectively. Both mAbs promoted killing by phagocytes in vitro, but prophylactic administration of only TRL186 increased mice survival. TRL186 improved survival also in a therapeutic mode. TRL186 but not TRL96 also impeded Shr binding to hemoglobin and GAS growth on hemoglobin iron.

Conclusions
Interference with iron acquisition is central for TRL186 efficacy against GAS. This study supports the concept of antibody-based immunotherapy targeting the heme uptake proteins to combat streptococcal infections.
Outcomes of Early and Intensive Use of a Palm and Digit Extension Orthosis in Young Children After Burn Injury
Authors: Thomas Rhianydd , Wicks Stephanie , Dale Marita , Pacey Verity 
Published: August 2020

Abstract
Burns to the palmar aspect of the hand are prevalent in young children. The development of scar tissue across the flexor surface of the hand combined with the years of growth ahead may result in considerable complications. This study was undertaken to describe outcomes of early and intensive use of a palm and digit extension orthosis with the elbow immobilized at 90° flexion following a palmar hand burn. A retrospective review of 107 children (mean age 18 months [SD 10]) treated at a statewide Pediatric Burns Unit from 2012 to 2016 was performed. Three children (3%) developed contracture during the 24-month study follow-up period. The other 104 children (97%) had full ROM at 24 months or at either the point of discharge or loss to follow-up. Early signs of contracture, defined as loss of full movement or significant banding, developed in 26 children (24%) in the first 9 months after burn. With intensive physiotherapy, 23 children regained full movement by 12 months after burn. Children who did not achieve complete wound healing at 1 month after burn and children with hypertrophic scarring at 2 months after burn were significantly more represented among cases of early signs of contracture (P = .013). When undertaken with regular clinical review, early and intensive use of a palm and digit extension orthosis can maintain full extension of the palm and digits in children after palmar burn.
Subversive Faith and Competition in Patronage: A Note on ΠΙΣΤΙΣ in Mark
Authors: Smit Peter-Ben 
Published: August 2020

Abstract
In her influential monograph Roman Faith and Christian Faith: Pistis and Fides in the Early Roman Empire and Early Churches, Theresa Morgan has convincingly shown how closely the early Christian discourse on ‘faith’ was bound up with similar notions in the broader Greco-Roman world, particularly in relation to the system of patronage, with both humans and deities fulfilling the role of (trustworthy and trusted) patrons. Thus, she has shifted attention from πίστις/fides as a primarily ‘theological’ notion to an interpretation along more ‘social’ lines and situated it in realm of human and divine/human relations. She also analyses this in relation to the Gospel of Mark, showing how Mark also fits this general picture. This note builds on Morgan’s work and will further develop one aspect of Mark’s use of the language (and concept) of patronage and πίστις. This is its subversive character, which is present to a lesser extent in Morgan's work; by calling for πίστις directed to him on the part of the people that he encounters, Jesus also draws these people away from other allegiances and ‘πίστις commitments’, that is, intersubjective relationships based on trust and leading to personal allegiance.
The tidal disruption event AT 2018hyz – I. Double-peaked emission lines and a flat Balmer decrement
Authors: Short P , Nicholl M , Lawrence A , Gomez S , Arcavi I , Wevers T , Leloudas G , Schulze S , Anderson J P , Berger E , Blanchard P K , Burke J , Segura N Castro , Charalampopoulos P , Chornock R , Galbany L , Gromadzki M , Herzog L J , Hiramatsu D , Horne Keith , Hosseinzadeh G , Howell D Andrew , Ihanec N , Inserra C , Kankare E , Maguire K , McCully C , Müller Bravo T E , Onori F , Sollerman J , Young D R 
Published: August 2020

ABSTRACT
We present results from spectroscopic observations of AT 2018hyz, a transient discovered by the All-Sky Automated Survey for Supernova survey at an absolute magnitude of MV ∼ −20.2 mag, in the nucleus of a quiescent galaxy with strong Balmer absorption lines. AT 2018hyz shows a blue spectral continuum and broad emission lines, consistent with previous TDE candidates. High cadence follow-up spectra show broad Balmer lines and He i in early spectra, with He ii making an appearance after ∼70–100 d. The Balmer lines evolve from a smooth broad profile, through a boxy, asymmetric double-peaked phase consistent with accretion disc emission, and back to smooth at late times. The Balmer lines are unlike typical active galactic nucleus in that they show a flat Balmer decrement (Hα/Hβ ∼ 1.5), suggesting the lines are collisionally excited rather than being produced via photoionization. The flat Balmer decrement together with the complex profiles suggests that the emission lines originate in a disc chromosphere, analogous to those seen in cataclysmic variables. The low optical depth of material due to a possible partial disruption may be what allows us to observe these double-peaked, collisionally excited lines. The late appearance of He ii may be due to an expanding photosphere or outflow, or late-time shocks in debris collisions.
A successful search for intervening 21 cm H i absorption in galaxies at 0.4 &lt; z &lt;1.0 with the Australian square kilometre array pathfinder (ASKAP)
Authors: Sadler Elaine M , Moss Vanessa A , Allison James R , Mahony Elizabeth K , Whiting Matthew T , Johnston Helen M , Ellison Sara L , Lagos Claudia del P , Koribalski Bärbel S 
Published: August 2020

ABSTRACT
We have used the Australian Square Kilometre Array Pathfinder (ASKAP) radio telescope to search for intervening 21 cm neutral hydrogen (H i) absorption along the line of sight to 53 bright radio continuum sources. Our observations are sensitive to H i column densities typical of Damped Lyman Alpha absorbers (DLAs) in cool gas with an H i spin temperature below about 300–500 K. The six-dish Boolardy Engineering Test Array (BETA) and twelve-antenna Early Science array (ASKAP-12) covered a frequency range corresponding to redshift 0.4 &lt; z &lt; 1.0 and 0.37 &lt; z &lt; 0.77, respectively, for the H i line. Fifty of the 53 radio sources observed have reliable optical redshifts, giving a total redshift path Δz = 21.37. This was a spectroscopically untargeted survey, with no prior assumptions about the location of the lines in redshift space. Four intervening H i lines were detected, two of them new. In each case, the estimated H i column density lies above the DLA limit for H i spin temperatures above 50–80 K, and we estimate a DLA number density at redshift z ∼ 0.6 of $n(z)=0.19^{+0.15 }_{ -0.09}$. This value lies somewhat above the general trend of n(z) with redshift seen in optical DLA studies. Although the current sample is small, it represents an important proof of concept for the much larger 21 cm First Large Absorption Survey in H i (FLASH) project to be carried out with the full 36-antenna ASKAP telescope, probing a total redshift path $\Delta z\sim \, 50,000$.
How dark are filaments in the cosmic web?
Authors: Yang Tianyi , Hudson Michael J , Afshordi Niayesh 
Published: August 2020

ABSTRACT
The cold dark matter model predicts that dark matter haloes are connected by filaments. Direct measurements of the masses and structure of these filaments are difficult, but recently several studies have detected these dark-matter-dominated filaments using weak lensing. Here we study the efficiency of galaxy formation within the filaments by measuring their total mass-to-light ratios and stellar mass fractions. Specifically, we stack pairs of luminous red galaxies (LRGs) with a typical separation on the sky of 8 h−1 Mpc. We stack background galaxy shapes around pairs to obtain mass maps through weak lensing, and we stack galaxies from the Sloan Digital Sky Survey to obtain maps of light and stellar mass. To isolate the signal from the filament, we construct two matched catalogues of physical and non-physical (projected) LRG pairs, with the same distributions of redshift and separation. We then subtract the two stacked maps. Using LRG pair samples from the Baryon Oscillation Spectroscopic Survey at two different redshifts, we find that the evolution of the mass in filament is consistent with the predictions from perturbation theory. The filaments are not entirely dark: Their mass-to-light ratios (M/L = 351 ± 137 in solar units in the rband) and stellar mass fractions (Mstellar/M = 0.0073 ± 0.0030) are consistent with the cosmic values (and with their redshift evolutions).
Radio frequency interference mitigation based on the asymmetrically reweighted penalized least squares and SumThreshold method
Authors: Zeng Qingguo , Chen Xue , Li Xiangru , Han J L , Wang Chen , Zhou D J , Wang Tao 
Published: August 2020

ABSTRACT
As radio telescopes become more sensitive, radio frequency interference (RFI) is becoming more important for interesting signals of radio astronomy. There is a demand for developing an automatic, accurate and efficient RFI mitigation method. Therefore, we have investigated an RFI detection algorithm. First, we introduce an asymmetrically reweighted penalized least squares (ArPLS) method to estimate the baseline more accurately. After removing the estimated baseline, several novel strategies were proposed based on the SumThreshold algorithm for detecting different types of RFI. The threshold parameter in SumThreshold can be determined automatically and adaptively. The adaptiveness is essential for reducing human intervention and for the online RFI processing pipeline. Applications to data from the Five-hundred-meter Aperture Spherical Telescope (FAST) show that the proposed scheme based on ArPLS and SumThreshold is superior to some typically available methods for RFI detection with respect to efficiency and performance.
Gas accretion regulates the scatter of the mass–metallicity relation
Authors: De Lucia Gabriella , Xie Lizhi , Fontanot Fabio , Hirschmann Michaela 
Published: August 2020

ABSTRACT
In this paper, we take advantage of the GAlaxy Evolution and Assembly (GAEA) semi-analytic model to analyse the origin of secondary dependencies in the local galaxy mass–gas metallicity relation. Our model reproduces quite well the trends observed in the local Universe as a function of galaxy star formation rate and different gas-mass phases. We show that the cold gas content (whose largest fraction is represented by the atomic gas phase) can be considered as the third parameter governing the scatter of the predicted mass–metallicity relation, in agreement with the most recent observational measurements. The trends can be explained with fluctuations of the gas accretion rates: a decrease of the gas supply leads to an increase of the gas metallicity due to star formation, while an increase of the available cold gas leads to a metallicity depletion. We demonstrate that the former process is responsible for offsets above the mass–metallicity relation, while the latter is responsible for deviations below the mass–metallicity relation. In low- and intermediate-mass galaxies, these negative offsets are primarily determined by late gas cooling dominated by material that has been previously ejected due to stellar feedback.
Redshift estimates for fast radio bursts and implications on intergalactic magnetic fields
Authors: Hackstein S , Brüggen M , Vazza F , Rodrigues L F S 
Published: August 2020

ABSTRACT
Fast radio bursts are transient radio pulses from presumably compact stellar sources of extragalactic origin. With new telescopes detecting multiple events per day, statistical methods are required in order to interpret observations and make inferences regarding astrophysical and cosmological questions. We present a method that uses probability estimates of fast radio burst observables to obtain likelihood estimates for the underlying models. Considering models for all regions along the line of sight, including intervening galaxies, we perform Monte Carlo simulations to estimate the distribution of the dispersion measure (DM), rotation measure (RM), and temporal broadening. Using Bayesian statistics, we compare these predictions to observations of fast radio bursts. By applying Bayes theorem, we obtain lower limits on the redshift of fast radio bursts with extragalactic DM ≳ 400 pc cm−3. We find that intervening galaxies cannot account for all highly scattered fast radio bursts in FRBcat, thus requiring a denser and more turbulent environment than an SGR 1935+2154-like magnetar. We show that a sample of ≳103 unlocalized fast radio bursts with associated extragalactic RM ≥ 1 rad m−2 can improve current upper limits on the strength of intergalactic magnetic fields.
The Lynden-Bell bar formation mechanism in simple and realistic galactic models
Authors: Polyachenko E V , Shukhman I G 
Published: August 2020

ABSTRACT
Using the canonical Hamilton–Jacobi approach we study the Lynden-Bell concept of bar formation based on the idea of orbital trapping parallel to the long or short axes of the oval potential distortion. The concept considered a single parameter – a sign of the derivative of the precession rate over angular momentum, determining the orientation of the trapped orbits. We derived a perturbation Hamiltonian that includes two more parameters characterizing the background disc and the perturbation, which are just as important as the earlier known one. This allows us to link the concept with the matrix approach in linear perturbation theory, the theory of weak bars, and explain some features of the non-linear secular evolution observed in N-body simulations.
Convective differential rotation in stars and planets – II. Observational and numerical tests
Authors: Jermyn Adam S , Chitre Shashikumar M , Lesaffre Pierre , Tout Christopher A 
Published: August 2020

ABSTRACT
Differential rotation is central to a great many mysteries in stars and planets. In part I, we predicted the order of magnitude and scaling of the differential rotation in both hydrodynamic and magnetohydrodynamic convection zones. Our results apply to both slowly and rapidly rotating systems, and provide a general picture of differential rotation in stars and fluid planets. We further calculated the scalings of the meridional circulation, entropy gradient, and baroclinicity. In this companion paper, we compare these predictions with a variety of observations and numerical simulations. With a few exceptions, we find that these are consistent in both the slowly rotating and rapidly rotating limits. Our results help to localize core–envelope shear in red giant stars, suggest a rotation-dependent frequency shift in the internal gravity waves of massive stars, and potentially explain observed deviations from von Zeipel’s gravity darkening in late-type stars.
TBDB: a database of structurally annotated T-box riboswitch:tRNA pairs
Authors: Marchand Jorge A , Pierson Smela Merrick D , Jordan Thomas H H , Narasimhan Kamesh , Church George M 
Published: August 2020

Abstract
T-box riboswitches constitute a large family of tRNA-binding leader sequences that play a central role in gene regulation in many gram-positive bacteria. Accurate inference of the tRNA binding to T-box riboswitches is critical to predict their cis-regulatory activity. However, there is no central repository of information on the tRNA binding specificities of T-box riboswitches, and de novo prediction of binding specificities requires advanced knowledge of computational tools to annotate riboswitch secondary structure features. Here, we present the T-box Riboswitch Annotation Database (TBDB, https://tbdb.io), an open-access database with a collection of 23,535 T-box riboswitch sequences, spanning the major phyla of 3,632 bacterial species. Among structural predictions, the TBDB also identifies specifier sequences, cognate tRNA binding partners, and downstream regulatory targets. To our knowledge, the TBDB presents the largest collection of feature, sequence, and structural annotations carried out on this important family of regulatory RNA.