bluuebunny/crossref_metadata_2025_split huggingface dataset:
Higher anhedonia and dysphoric arousal relate to lower relationship satisfaction among trauma‐exposed female service members/veterans
Authors: Blais Rebecca K. 
Published: February 2020

AbstractObjectivePosttraumatic stress disorder (PTSD) symptoms of detachment, anhedonia, and hyperarousal are associated with poorer relationship satisfaction. Such findings are limited to earlier models of PTSD and samples that were almost exclusively male. The association of current PTSD symptom clusters with relationship satisfaction in partnered female service members/veterans (SM/Vs) are understudied.MethodsThis study examined the association of PTSD (PTSD Checklist‐5 [PCL‐5]) symptom clusters identified in the anhedonia model and relationship satisfaction (Couples’ Satisfaction Index‐4) in 477 partnered female SM/Vs.ResultsHigher anhedonia and dysphoric arousal were associated with lower relationship satisfaction. Among those who scored 31+ on the PCL‐5 (n = 255, 53.46%), which is a suggested cutoff for a probable PTSD diagnosis, only higher anhedonia was associated with poorer relationship satisfaction.ConclusionsThe association of PTSD symptom clusters with relationship satisfaction are similar for male and female SM/Vs. Interventions to improve relationship satisfaction may focus on reducing anhedonia and dysphoric arousal.
Different patterns of perceived barriers to psychological treatment among Chinese depressed college students: Preliminary findings
Authors: Wu Liyang , Wang Jun , Gao Yuhan , Zhu Lei 
Published: February 2020

AbstractObjectivesThis study aimed to (a) identify the different patterns of perceived barriers to psychological treatment in Chinese college students with depression and (b) determine whether self‐compassion and depression severity distinguished individuals with different patterns.MethodsThis study included 338 college students with depression. The perceived barriers to psychological treatment scale were used. Latent profile analysis (LPA) was performed to identify the differential patterns.ResultsResults of LPA indicated four patterns of perceived barriers, which differed with respect to levels and patterns, namely, “low barriers” (31%, n = 105), “moderate barriers” (45%, n = 153), “attitudinal and availability barriers” (18%, n = 61), and “high barriers” (6%, n = 19). Self‐compassion (particularly, negative self‐compassion) and depression severity distinguished participants with the four patterns.ConclusionsA small number of participants reporting high levels across different types of barriers deserve special attention because they would be less likely to seek professional help.
Omega‐3 and Omega‐6 polyunsaturated fatty acids stimulate vascular differentiation of mouse embryonic stem cells
Authors: Taha Amer , Sharifpanah Fatemeh , Wartenberg Maria , Sauer Heinrich 
Published: February 2020

AbstractPolyunsaturated fatty acids (PUFAs) and their metabolites may influence cell fate regulation. Herein, we investigated the effects of linoleic acid (LA) as ω‐6 PUFA, eicosapentaenoic acid (EPA) as ω‐3 PUFA and palmitic acid (PA) on vasculogenesis of embryonic stem (ES) cells. LA and EPA increased vascular structure formation and protein expression of the endothelial‐specific markers fetal liver kinase‐1, CD31 as well as VE‐cadherin, whereas PA was without effect. LA and EPA increased reactive oxygen species (ROS) and nitric oxide (NO), activated endothelial NO synthase (eNOS) and raised intracellular calcium. The calcium response was inhibited by the intracellular calcium chelator BAPTA, sulfo‐N‐succinimidyl oleate which is an antagonist of CD36, the scavenger receptor for fatty acid uptake as well as by a CD36 blocking antibody. Prevention of ROS generation by radical scavengers or the NADPH oxidase inhibitor VAS2870 and inhibition of eNOS by L‐NAME blunted vasculogenesis. PUFAs stimulated AMP activated protein kinase‐α (AMPK‐α) as well as peroxisome proliferator‐activated receptor‐α (PPAR‐α). AMPK activation was abolished by calcium chelation as well as inhibition of ROS and NO generation. Moreover, PUFA‐induced vasculogenesis was blunted by the PPAR‐α inhibitor GW6471. In conclusion, ω‐3 and ω‐6 PUFAs stimulate vascular differentiation of ES cells via mechanisms involving calcium, ROS and NO, which regulate function of the energy sensors AMPK and PPAR‐α and determine the metabolic signature of vascular cell differentiation.
Dissolution kinetics of calcium vanadates in sulfuric acid: a fundamental study for the vanadium extraction process
Authors: Huang Qingyun , Xiang Junyi , Wang Xin , Pei Guishang , Lv Xuewei 
Published: February 2020

AbstractBACKGROUNDThe dissolution behavior of calcium vanadates is vital for the vanadium extraction process, as well as the utilization of calcium vanadates based function materials. Therefore, the dissolution kinetics study of calcium vanadates (CaV2O6, Ca2V2O7, and Ca3V2O8) in sulfuric acid are presented. The effects of stirring speed, solid/liquid ratio, pH, and temperature on the dissolution rate of calcium vanadates were determined. The mineralogical and microstructure of the residue after dissolution are also performed.RESULTSThe results showed that the dissolution rate of calcium vanadates significantly increased with the increase of temperature from 30 to 70 °C. Under the conditions with solid/liquid ratio of 1:150 g mL−1, temperature range of 30 to 70 °C, and pH of 4, the rate of Ca3V2O8 dissolution is the fastest, followed by Ca2V2O7 and CaV2O6, especially at low temperature.CONCLUSIONThe mineralogical analyses results showed that the main products for the dissolution of Ca2V2O7 and Ca3V2O8 are needle‐like CaSO4·0.5H2O, whereas for CaV2O6 are undissolved CaV2O6 and hydrolyzed V2O5. The dissolution kinetics indicate that the dissolution of CaV2O6 follows second‐order pseudo‐homogeneous model, whilst Ca2V2O7 and Ca3V2O8 follow the diffusion through the product or ash layer model. The apparent activation energies for the dissolution of CaV2O6, Ca2V2O7, and Ca3V2O8 were determined as 46.44, 38.72, and 23.50 kJ mol−1, respectively. © 2020 Society of Chemical Industry
Runoff water quality after low‐disturbance manure application in an alfalfa–grass hay crop forage system
Authors: Sherman Jessica F. , Young Eric O. , Coblentz Wayne K. , Cavadini Jason 
Published: February 2020

AbstractThe impacts of low‐disturbance manure application (LDMA) on runoff water quality in hay crop forages are not well known. Our objective in this study was to determine surface runoff losses of total nitrogen (TN), ammonium N (NH4–N), nitrate N (NO3–N), total phosphorus (TP), dissolved reactive P (DRP), and suspended sediment from alfalfa (Medicago sativa L.)–grass plots in central Wisconsin after surface broadcasting manure and LDMA compared with no application. Treatments were (a) surface banding (BAND), (b) surface banding with aeration (A/B), (c) shallow disk injection (INJECT), (d) surface broadcast (BCAST), and (e) a no‐manure control (CONT). Runoff events were generated (n = 7) from replicated plots following a standardized rainfall simulation protocol. Although runoff was variable across plots and within treatments, mean runoff concentrations of TN (P = .03), NH4–N (P = .03), TP (P = .001), and DRP (P < .0001) were lower for incorporated (INJECT and A/B) vs. unincorporated (BCAST and BAND) treatments. INJECT had lower mean DRP concentration (P = .02) than A/B and was similar to CONT and had lower cumulative TN (P = .05), TP (P = .07), and DRP (P = .01) loads than A/B. Additionally, TP, TN, DRP, and NH4–N loads and concentrations were strongly related with soil surface manure coverage extent (R2 = 0.50–0.84; P < .0001), suggesting that manure was a main source of N and P losses. Although INJECT appeared to be the most effective in mitigating nutrient loss in surface runoff, more research is needed to determine LDMA impacts on farm economics, soil properties, and runoff water quality.
Identification of a recurrent nonsense mutation in HR gene responsible for atrichia with papular lesions in two Kashmiri families
Authors: Ali Ghazanfar , Awan Naheed Bashir , Sadia  , Khawaja Abdul Waheed , Foo Jia Nee , Khor Chiea Chuen , Chang Chu‐Hua , Chew Elaine GuoYan , Kiani Farhat Rafique , Jelani Musharraf 
Published: February 2020

AbstractBackgroundCongenital atrichia (CA) is a rare form of irreversible alopecia with an autosomal recessive mode of inheritance. This form of hair loss is mainly associated with mutations in the human hairless (HR) gene located at chromosome 8p21.3. An additional unique feature atrichia with papular lesions (APL) comprises keratin‐filled cysts known as papules. The present study aimed to uncover the underlying genetic causes of APL in two consanguineous Kashmiri families.MethodsIn the present study, two consanguineous families of Kashmiri origin with APL displaying an autosomal recessive mode of inheritance were investigated. Whole exome and Sanger sequencing followed by bioinformatic studies, variant prioritization, Sanger validation and segregation analysis was performed to find the mutation.ResultsA recurrent nonsense (NM_005144: c.2818C > T:p.Arg940*) mutation was detected in exon 13 of the human HR gene.ConclusionsWhole exome sequencing analysis has widely been used in the screening of single gene disorders mutations, both in research and diagnostic laboratories. Sanger sequencing alone for genes such as HR becomes expensive and time consuming. Instead, it is recommended that a patient is to screen by whole exome sequencing and then special attention first focuses on known genes of the APL phenotype. This is helpful for intime diagnosis, being more efficient and economic. The results obtained in the present study may contribute to prenatal diagnosis, carrier secreening and the genetic counseling of families with the APL phenotype in Kashmiri poplution.
Syringaldehyde as a scaffold for the synthesis of some biologically potent heterocycles
Authors: Youssef Ahmed S. A. , Hemdan Magdy M. , Azab Mohammad E. , Emara Samir A. , Elsayed Galal A. , Kamel Rabaa M. 
Published: February 2020

AbstractSyringaldehyde was utilized in synthesis of different heterocyclic systems. Some of the synthesized compounds 2, 7, 8, 10, 11, and 13 were tested for antioxidant activity where they showed ability to inhibit oxidation in kidney and rat brain homogenates using 2, 2′‐azinobis (3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS). Also, the activity against cancer was examined using the standard MTT method for two human tumor cell lines namely; mammary gland breast cancer MCF‐7 and hepatocellular carcinoma HepG2. The highest activity as antioxidant and antitumor agents was exhibited by compounds 8 and 11. However, moderate activities were shown by compounds 10 and 13. While, compounds 2, 7 showed weak activities.
Reply to “Intrapatient Comparison of the Hepatobiliary Phase of Gd‐BOPTA and Gd‐EOB‐DTPA in the Differentiation of Hepatocellular Adenoma From Focal Nodular Hyperplasia”
Authors: Reizine Edouard , Luciani Alain 
Published: February 2020

Level of Evidence5Technical Efficacy Stage3Conflict of InterestNone.Financial supportNone. J. Magn. Reson. Imaging 2020;52:1279–1280.
Optimising patient care in medical radiation services through health economics: an introduction
Authors: Jones Scott , Brown Amy , Barclay Vanessa , Reardon Oona 
Published: February 2020

AbstractThe role of health economics in optimising patient care in medical radiation clinical settings is of increasing importance in ensuring efficient and effective service delivery. This commentary introduces health economics to medical radiation professionals by outlining the main analysis types utilised, highlighted by examples in the literature. The purpose is to provide an over‐arching framework and starting point for incorporating health economics into medical radiation research study protocols.
Immunoinformatics‐aided identification of T cell and B cell epitopes in the surface glycoprotein of 2019‐nCoV
Authors: Baruah Vargab , Bose Sujoy 
Published: February 2020

AbstractThe 2019 novel coronavirus (2019‐nCoV) outbreak has caused a large number of deaths with thousands of confirmed cases worldwide, especially in East Asia. This study took an immunoinformatics approach to identify significant cytotoxic T lymphocyte (CTL) and B cell epitopes in the 2019‐nCoV surface glycoprotein. Also, interactions between identified CTL epitopes and their corresponding major histocompatibility complex (MHC) class I supertype representatives prevalent in China were studied by molecular dynamics simulations. We identified five CTL epitopes, three sequential B cell epitopes and five discontinuous B cell epitopes in the viral surface glycoprotein. Also, during simulations, the CTL epitopes were observed to be binding MHC class I peptide‐binding grooves via multiple contacts, with continuous hydrogen bonds and salt bridge anchors, indicating their potential in generating immune responses. Some of these identified epitopes can be potential candidates for the development of 2019‐nCoV vaccines.
Characterizing precipitation in high altitudes of the western Tibetan plateau with a focus on major glacier areas
Authors: Li Duo , Yang Kun , Tang Wenjun , Li Xin , Zhou Xu , Guo Donglin 
Published: February 2020

AbstractSolid water resources such as glaciers and snow cover are widely distributed in the western Tibetan plateau (WTP), and precipitation is the key supply of them. However, the characteristics of precipitation over the WTP remain unclear due to sparse observations. Using observation‐based gridded data (APHRODITE, GPCC), satellite products (TRMM, GPM), reanalysis data (ERA5, ERA‐Interim, JRA‐55) and weather research and forecasting model (WRF)‐simulation data (HAR10, HAR30), this study investigated the precipitation characteristics in high mountain areas (altitude >2,500 m a.s.l.) of the WTP (26–44°N, 70–85°E) from 2001 to 2013. Results show that annual GPM precipitation (336 mm) is much lower than that of other data sets (570–800 mm) for the WTP and appears to be an outlier; meanwhile, the other data sets show increasing precipitation as grid resolution decreases (becomes coarser). In contrast, high spatial resolution WRF simulations (HAR10, HAR30) yielded considerably higher precipitation in four strongly glacierized alpine areas (Western Himalaya, Karakorum, Tajikistan, and west Kunlun) than the other data sets. When compared to precipitation estimated using the water balance in nine glacierized catchments of the Upper Indus River Basin, the HAR data sets more reasonably represent the amount of precipitation in high mountain areas than the other data sets. The surface albedo, snow cover extent, and snow cover duration observed by satellites further indicate that the HAR data sets yield reasonable spatial variability of precipitation. This implies that the commonly used data sets (such as observation data and satellite products) underestimate the precipitation in high mountain areas. According to the HAR10 data, the four major glacierized areas on the WTP have similar precipitation amounts in summer and autumn, and the winter–spring contribution to annual precipitation is at least 70% in three of these areas (Western Himalaya, Karakorum, and Tajikistan). This pattern indicates that precipitation over the high‐altitude areas in WTP is mainly controlled by the mid‐latitude westerlies. The annual precipitation in these areas is over 1,000 mm, which is comparable to that of the southeast TP but much larger than that on the central plateau. Therefore, the spatial precipitation pattern across the TP is ‘wet east and west, dry middle’.
Selection of tomato landraces with high fruit yield and nutritional quality under elevated temperatures
Authors: Scarano Aurelia , Olivieri Fabrizio , Gerardi Carmela , Liso Marina , Chiesa Maurizio , Chieppa Marcello , Frusciante Luigi , Barone Amalia , Santino Angelo , Rigano Maria Manuela 
Published: February 2020

AbstractBACKGROUNDGlobal warming and extreme or adverse events induced by climatic fluctuations are an important threat for plants growth and agricultural production. Adaptability to environmental changes prevalently derives from a large set of genetic traits affecting physiological and agronomic parameters. Therefore, the identification of genotypes that are good yield performer at high temperatures is becoming increasingly necessary for future breeding programs. Here, we analyzed the performances of different tomato landraces grown under elevated temperatures in terms of yield and nutritional quality of the fruit. Finally, we evaluated the antioxidant and anti‐inflammatory activities of fruit extracts from the tomato landraces selected.RESULTSThe tomato landraces analyzed here in a hot climate differed in terms of yield performance, physicochemical parameters of fruit (pH, titratable acidity, degrees Brix, firmness), bioactive compounds (ascorbic acid, carotenoids, and polyphenols), and anti‐inflammatory potential. Three of these landraces (named E30, E94, and PDVIT) showed higher fruit quality and nutritional value. An estimated evaluation index allowed identification of PDVIT as the best performer in terms of yield and fruit quality under high temperatures.CONCLUSIONThe analyses performed here highlight the possibility to identify new landraces that can combine good yield performances and fruit nutritional quality at high temperatures, information that is useful for future breeding programs. © 2020 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Oncoplastic mammaplasty with geometric compensation: Evolution of the technique, outcomes and follow‐up in a multicentre retrospective cohort
Authors: Resende Paulinelli Régis , de Oliveira Vilmar Marques , Bagnoli Fábio , Letzkus Berríos Jaime , Cézar Chade Milca , Bragatto Picoli Larissa , Dias Santos Thauana , Bastos de Carvalho Ana Paula , Jubé Ribeiro Luiz Fernando , Freitas‐Junior Ruffo 
Published: February 2020

AbstractBackground and ObjectivesTo report on the outcomes and evolution of an oncoplastic mammaplasty referred to as geometric compensation mammaplasty.MethodsSeventy‐three patients with malignant tumours were operated on and followed up in five centres in two countries. Preoperative markings were performed using a Wise pattern. The resection of affected skin was geometrically compensated using another area of preserved skin.ResultsMean pathological tumour size was 30.42 ± 21.98 mm. Twenty tumours (30.77%) were locally advanced and 15 (20.55%) were multicentric. Twenty‐two patients (34.38%) were submitted to neoadjuvant chemotherapy. Cosmetic results were considered good or excellent in 59 cases (80.82%). Margins were positive in two cases (2.74%). Complications were partial wound dehiscence (n = 11; 15.07%), fat necrosis (n = 9; 12.33%), skin necrosis (n = 5; 6.85%), seromas (n = 5; 6.85%), enlarged scars (n = 7; 9.59%) and infection (n = 2; 2.74%). There were three cases of local recurrence (4.29%), two of bone metastasis (2.86%) and three of metachronous contralateral breast cancer (4.35%). No deaths were recorded within a mean follow‐up of 35.33 ± 28.21 months.ConclusionsThe technique allowed breast conservation in situations requiring a large resection of skin in difficult positions, with a high rate of free margins, correction of ptosis, satisfactory symmetry and few complications.
The moderating role of leisure participation in work–leisure conflict for the reduction of burnout in hotels and travel agencies
Authors: Elbaz Ahmed M. , Salem Islam , Elsetouhi Ahmed , Abdelhamied Hany H. S. 
Published: February 2020

AbstractThis study investigates the influence of work–leisure conflict (WLC) on the performance of employees in Egyptian hotels and travel agencies through the mediating role of employee burnout related to emotional exhaustion, cynicism and professional efficacy. In addition, this study examines how leisure participation moderates the effects of WLC on both employee burnout and performance. Data used for this study were collected from 788 hotel and travel agencies operating in Egypt. Given the purpose of the study, a nonlinear partial least squares structural equation modelling (PLS‐SEM) was used to analyse the data. The findings support the proposed model and thus indicated that WLC has a negative influence on the performance of employees. Moreover, it has also been determined that leisure participation plays an important role in decreasing the negative influence of WLC on emotional exhaustion, cynicism and reduced professional efficacy of employees in hotels and travel agencies. These findings hold important implications for tourism and hospitality firms.
Optimizing Settings for Office‐Based Endoscopic CO2 Laser Surgery Using an Experimental Vocal Cord Model
Authors: Schimberg Anouk S. , Klabbers Tim M. , Wellenstein David J. , Heutink Floris , Honings Jimmie , van Engen‐Van Grunsven Ilse , Verdaasdonk Rudolf M. , Takes Robert P. , van den Broek Guido B. 
Published: February 2020

Objectives/HypothesisTo provide insight in the thermal effects of individual laser settings in target tissues to optimize flexible endoscopic CO2 laser surgery treatment.Study DesignExperimental laboratory study.MethodsThermal effects of the CO2 laser using a fiber delivery system were visualized using the color Schlieren technique in combination with a polyacrylamide gel tissue model. Variable settings were used for emission mode, power, laser fiber distance, and laser duration, which were evaluated in every possible combination. Collateral thermal expansion and incision depth were measured. To validate the model, the results were compared to histology after CO2 laser irradiation of ex vivo human vocal cords, and the intraclass correlation coefficient was calculated. Thermal damage and incision depth were measured by a blinded pathologist.ResultsOf all parameters studied, duration of laser irradiation had the greatest effect on thermal expansion. Increased distance between laser tip and target tissue resulted in significantly reduced incision depth and increased thermal expansion. Pulsed emission modes led to increased incision depths. The intraclass correlation coefficient for consistency between the model setup and the ex vivo human vocal cords was classified as “fair.”ConclusionsBy using high‐intensity pulsed lasers at minimal distance to the target tissue, exposure times and subsequent damage to surrounding tissue can be reduced. If an evaporation technique is used, lower power in continuous wave at a larger distance to the target tissue will lead to superficial but broader thermal effects. The model setup used in this study is a valid model to investigate laser‐induced thermal effects in vocal cord tissue.Level of EvidenceNA Laryngoscope, 130:E680–E685, 2020