bluuebunny/crossref_metadata_2025_split huggingface dataset:
Octoploid zoysiagrass: Origin, stability, characteristics, and breeding behavior
Authors: Quesenberry Kenneth , Kenworthy Kevin , Buhlman Jamie , Chase Kathryn , Carter Zach , Benda Nicole 
Published: August 2020

AbstractAll known species of zoysiagrass are tetraploids (2n = 4x = 40) but octoploids have been reported. This research was conducted to evaluate ploidy variability from a stand of zoysiagrass where an 8xclone (E11) originated, and to characterize progeny from E11 and other ploidy variable clones. Clone ploidy was determined by flow cytometry and clones and progeny were assessed for aboveground and belowground morphological variability. Clone E11 was confirmed as 8xwith a G1 peak twice that of ‘SS‐500’ (Empire, Sod Solutions, Inc.). Among 31 clones from the field where E11 originated, 20 were tetraploid, but 11 showed two flow cytometry peaks of similar numbers of events – one at a 4xvalue like Empire and a second at an 8xvalue like E11. From the group of 11 clones, three clones (C62, C96, and C107) that initially had double peaks reverted back to the 4xlevel, two (C92 and C105) stabilized at 8x, and six (C4‐1, B10, C13, I31, C87, and C93) continued to show double peaks. Progeny from C62 and C96 were only 4x. Progeny from the E11, C92, and C105 were all 8xexcept for one 6xplant among eight progeny of C105. Progeny from two clones with double peaks (C4‐1 and C93) were only 8x. These results show that, with variable ploidy of histogenic layers, a progeny generation is needed to stabilize 8xlines. Morphology studies showed that E11 generally followed the expected trend of increased size of vegetative and floral parts and root morphology found with chromosome doubling.
Analysis of capacitance spread reduction techniques for 50‐Hz switched‐capacitor notch filters
Authors: Serra Hugo , Oliveira João Pedro , Paulino Nuno 
Published: August 2020

SummaryThis paper presents an overview of design techniques to reduce the capacitance spread of SC notch filters. Three of these techniques are used in the design of a 50‐Hz notch filter, intended for an internet of things (IoT) water management sensor node. In this application, due to the high sampling frequency required by the acquisition channel's ADC, the filter's Fs/fp ratio becomes excessively large, resulting in a capacitance spread of 3225.8, if a conventional SC implementation is used. Using charge division networks, with up to seven share/reset cycles, the filter's capacitance spread is reduced by a factor 12.9 and the total capacitance by 5.9, and a total power dissipation of approximately 262 μW, for a supply voltage of 0.9 V. Using capacitive T‐cell networks, the filter's capacitance spread is reduced by a factor 40.5 and the total capacitance by 14.2. Using partial charge transfer networks, the filter's capacitance spread is improved by a factor 41.6, and the total capacitance by 10.0. The filter's total power consumption, using the last two techniques, is approximately 11 μW.
OMIP‐069: Forty‐Color Full Spectrum Flow Cytometry Panel for Deep Immunophenotyping of Major Cell Subsets in Human Peripheral Blood
Authors: Park Lily M. , Lannigan Joanne , Jaimes Maria C. 
Published: August 2020

PURPOSE AND APPROPRIATE SAMPLE TYPESThis 40‐color flow cytometry‐based panel was developed for in‐depth immunophenotyping of the major cell subsets present in human peripheral blood. Sample availability can often be limited, especially in cases of clinical trial material, when multiple types of testing are required from a single sample or timepoint. Maximizing the amount of information that can be obtained from a single sample not only provides more in‐depth characterization of the immune system but also serves to address the issue of limited sample availability. The panel presented here identifies CD4 T cells, CD8 T cells, regulatory T cells, γδ T cells, NKT‐like cells, B cells, NK cells, monocytes and dendritic cells. For each specific cell type, the panel includes markers for further characterization by including a selection of activation and differentiation markers, as well as chemokine receptors. Moreover, the combination of multiple markers in one tube might lead to the discovery of new immune phenotypes and their relevance in certain diseases. Of note, this panel was designed to include only surface markers to avoid the need for fixation and permeabilization steps. The panel can be used for studies aimed at characterizing the immune response in the context of infectious or autoimmune diseases, monitoring cancer patients on immuno‐ or chemotherapy, and discovery of unique and targetable biomarkers. Different from all previously published OMIPs, this panel was developed using a full spectrum flow cytometer, a technology that has allowed the effective use of 40 fluorescent markers in a single panel. The panel was developed using cryopreserved human peripheral blood mononuclear cells (PBMC) from healthy adults (Table 1). Although we have not tested the panel on fresh PBMCs or whole blood, it is anticipated that the panel could be used in those sample preparations without further optimization. @ 2020 Cytek Biosciences, Inc. Cytometry Part A published by Wiley Periodicals LLC on behalf of International Society for Advancement of Cytometry.
Fine‐needle aspiration of parathyroid adenomas: Indications as a diagnostic approach
Authors: Suzuki Ayana , Hirokawa Mitsuyoshi , Kanematsu Risa , Tanaka Aki , Yamao Naoki , Higuchi Miyoko , Hayashi Toshitetsu , Kuma Seiji , Miya Akihiro , Miyauchi Akira 
Published: August 2020

AbstractBackgroundWe aimed to determine the indication of fine‐needle aspiration (FNA) for parathyroid adenoma (PA)‐suspected nodules and the cytological features of PA, and to discuss the ancillary techniques for diagnostic confirmation.MethodClinical, cytological, and histological examinations of 15 PA patients (4.0% of all PA resected patients) were conducted through FNA on 16 nodules. We also examined the cytological preparations of 10 follicular neoplasms (FNs) and 10 poorly differentiated thyroid carcinomas (PDTCs).ResultsFNA was performed to detect PA in nine (56.3%) nodules. The remaining seven (43.8%) nodules underwent FNA for lesions considered as thyroid nodules or lymph nodes. The levels of parathyroid hormone (PTH) in the aspiration needle washout fluid were observably high, except for that from one nodule with unsatisfactory FNA. Cytologically, the incidences of wedge pattern (86.7%) and salt and pepper chromatin (86.7%) in PAs were significantly higher than in FNs and PDTCs. In contrast, the appearance of colloid globules and nuclear grooves was less frequent than that of FNs and PDTCs. GATA‐3 expression was intense in all PAs that immunocytochemistry were performed. Histologically, capsular invasion and/or laceration, tumor seeding, granulation tissue, and fibrosis were observed.ConclusionsWhen PA localization is unusual or inconclusive despite extensive imaging, FNA may be performed. We asserted that wedge pattern, salt and pepper chromatin, and the absence of colloid globules and nuclear grooves are diagnostic cytological indicators of PA rather than of FN or PDTC. We recommend PTH measurements using needle washout fluid for PA‐suspected nodules, and immunocytochemistry with the GATA‐3 antibody for cytologically PA‐suspected nodules.
Analytical profile of N‐ethyl‐N‐cyclopropyl lysergamide (ECPLA), an isomer of lysergic acid 2,4‐dimethylazetidide (LSZ)
Authors: Brandt Simon D. , Kavanagh Pierce V. , Westphal Folker , Stratford Alexander , Elliott Simon P. , Dowling Geraldine , Halberstadt Adam L. 
Published: August 2020

AbstractRecent investigations have shown that N‐ethyl‐N‐cyclopropyl lysergamide (ECPLA) produces LSD‐like behavioral effects in mice, which suggests that it may act as a hallucinogen in humans. Although the use of ECPLA as a recreational drug has been limited, key analytical data that can be used to detect ECPLA are required for future forensic and clinical investigations. ECPLA is an isomer of (2′S,4′S)‐lysergic acid 2,4‐dimethylazetidide (LSZ), a lysergamide that emerged as a recreational drug in 2013. Several analytical approaches were examined, including single‐ and tandem mass spectrometry platforms at low and high resolution, gas‐ and liquid chromatography (GC, LC), nuclear magnetic resonance spectroscopy (NMR), and GC condensed‐phase infrared spectroscopy (GC‐sIR). ECPLA and LSZ could be differentiated by NMR, GC‐sIR, GC, and LC‐based methods. The electron ionization mass spectra of ECPLA and LSZ contained ion clusters typically observed with related lysergamides such as m/z 150–155, m/z 177–182, m/z 191–197, m/z 205–208, and m/z 219–224. One of the significant differences in abundance related to these clusters included ions at m/z 196 and m/z 207/208. The base peaks were detected at m/z 221 in both cases followed by the retro‐Diels‐Alder fragment at m/z 292. Minor but noticeable differences between the two isomers could also be seen in the relative abundance of m/z 98 and m/z 41. Electrospray ionization mass spectra included lysergamide‐related ions at m/z 281, 251, 223, 208, 197, 180, and 140. LSZ (but not ECPLA) showed product ions at m/z 267 and m/z 98 under the conditions used.
The density characteristics of CO2 and alkane mixtures using PC‐SAFT EoS
Authors: Chi Yuan , Liu Shuyang , Jian Weiwei , Zhao Changzhong , Lv Junchen , Zhang Yi 
Published: August 2020

AbstractThe density of CO2 + crude oil mixtures is one of the most important parameters influencing CO2 diffusion and migration in oil reservoirs. However, it would be quite time consuming to obtain comprehensive density data for CO2 + alkane mixtures over a wide range of temperatures and pressures via experimental methods, therefore the development of a reliable model for predicting the densities of various CO2 + alkane mixtures with high accuracy is crucial. In this paper, the parameters (m, σ, and ε/k) in the perturbed‐chain statistical associating fluid theory (PC‐SAFT) Equation of State (EoS) were optimized by correlating density data of pure n‐alkanes from heptane to nonadecane (except undecane and hexadecane). For comparison, the G‐S PC‐SAFT and HTHP PC‐SAFT EoS(s) were also employed to fit the densities of these n‐alkanes, and the results demonstrated that the PC‐SAFT EoS with the optimized parameters in this study exhibited superior accuracy. Subsequently, by correlating density data of CO2 + alkane mixtures containing C7–C14 alkanes, the binary interaction parameter kij was optimized. Furthermore, for the first time, correlations between the optimized parameters (m, σ, ε/k, and kij) and alkane carbon number (n) were established. These correlations provided PC‐SAFT EoS with a good universality and scalability for density prediction. Using the parameters calculated from these correlations, the densities of hexadecane and saturated CO2 + alkane mixtures containing C10–C20 alkanes were successfully predicted with relatively high accuracy. This work provides a new way for modeling the thermodynamic properties of CO2 + alkane mixtures. © 2020 Society of Chemical Industry and John Wiley & Sons, Ltd.
Psychometric properties of the self‐efficacy for managing mild cognitive impairment scale
Authors: Kurasz Andrea M. , DeFeis Brittany , Locke Dona E. C. , De Wit Liselotte , Amofa Priscilla , Smith Glenn , Chandler Melanie 
Published: August 2020

ObjectivesWe adapted a self‐efficacy measure for managing chronic illness to be specific to persons with mild cognitive impairment (pwMCI). The aim of this study was to investigate the psychometric properties of the scale, the self‐efficacy for managing MCI scale, for use in research.MethodsAnalyses involved data from pwMCI enrolled in a behavioral intervention study that completed the measure five times from intervention enrollment to 18‐month post‐intervention. Factor structure, construct validity, internal consistency, and test‐retest reliability were analyzed.ResultsFactor analysis identified two factors, related to self‐efficacy for daily activities and managing MCI, which corresponded with domains from the original chronic illness self‐efficacy scale. Consistent with prior research, construct validity analysis suggested an association between memory‐loss self‐efficacy and psychosocial distress, but not cognitive or functional ability. Further analyses supported the scale's internal and test‐retest reliability.ConclusionsCurrently, no “gold standard” scale of memory‐loss self‐efficacy for pwMCI exists, despite the positive impact self‐efficacy may have on modifiable health behaviors. Overall, results supported the notion that the scale is a valid and reliable measure of memory‐loss self‐efficacy for pwMCI.
The therapeutic effects and safety of bright light therapy combined with escitalopram oxalate on insomnia in patients with poststroke depression
Authors: Xiao Meijuan , Feng Liang , Wang Qiongzhang , Luan Xiaoqian , Chen Siyan , He Jincai 
Published: August 2020

IntroductionBright light therapy (BLT) is known to treat depression and sleep disorders in clinical practice, but its efficacy on poststroke depression (PSD) has not been studied.ObjectiveTo investigate the therapeutic effects and safety of BLT combined with escitalopram oxalate (ESC) on insomnia in patients with PSD.MethodsIschemic stroke patients with depressive symptoms and a score of ≥8 on the Hamilton Depression Scale (HAMD‐17) while meeting DSM‐IV criteria were diagnosed as having PSD. A total of 112 PSD patients with symptoms of insomnia were randomly assigned to polytherapy (BLT plus ESC) and monotherapy (ESC only) groups. Each regimen continued for 6 weeks. The primary outcomes were a change in scores on the Pittsburgh Sleep Quality Index (PSQI) and a remission rate (PSQI ≤7 at the endpoint). The secondary outcomes included changes in the HAMD‐17 and Barthel Index (BI) scores. Adverse effects were assessed by the Adverse Events Scale.ResultsThe endpoint assessment included 106 patients (monotherapy, 54; polytherapy, 52). The mean changes in the PSQI scores for the monotherapy and polytherapy groups were 4.85 (1.47) and 5.87 (1.72) (P = 0.001), respectively. Compared to monotherapy, polytherapy improved PSQI remission rate (71.4% vs 50.0%; χ2 = 5.390; P = 0.020), and HAMD‐17 score (6.70 [2.12] vs 4.75 [1.98]; P < 0.001). Both treatments improved BI score, with no statistical difference, and were well tolerated, with few significant differences in treatment‐associated adverse events.ConclusionBLT combined with ESC is effective and well tolerated for the treatment of PSD‐associated insomnia.
Elective neck dissection for T3/T4 cN0 sinonasal squamous cell carcinoma
Authors: Crawford Kayva L. , Jafari Aria , Qualliotine Jesse R. , Stuart Emelia , DeConde Adam S. , Califano Joseph A. , Orosco Ryan K. 
Published: August 2020

AbstractBackgroundIn locally advanced sinonasal squamous cell carcinoma (SNSCC), management of the clinically node‐negative (cN0) neck is variable and elective neck dissection (END) remains controversial.MethodsPatients with surgically treated T3/T4 cN0 M0 SNSCC were identified using the NCDB. Overall survival (OS) was assessed by Cox proportional hazard analysis in propensity score‐matched cohorts. Factors associated with END were evaluated with logistic regression.ResultsTwo hundred twenty patients underwent END (19.6%). END did not correlated with OS in propensity score‐matched cohorts (HR 0.971, 95% CI 0.677‐1.392), a maxillary sinus tumor subgroup (HR 1.089, 95% CI 0.742‐1.599), or by radiation status [radiation: (HR 0.802, 95% CI 0.584‐1.102); no radiation: (HR 0.852, 95% CI 0.502‐1.445)]. The occult metastasis rate in the END cohort was 12.7%.ConclusionEND did not significantly improve OS in this study. Further information on disease‐free survival is necessary to determine its role in advanced‐stage SNSCC.
The ratio of posterior–anterior medial temporal lobe volumes predicts source memory performance in healthy young adults
Authors: Snytte Jamie , Elshiekh Abdelhalim , Subramaniapillai Sivaniya , Manning Lyssa , Pasvanis Stamatoula , Devenyi Gabriel A. , Olsen Rosanna K. , Rajah Maria Natasha 
Published: August 2020

AbstractA functional gradient has been proposed across the medial temporal lobes (MTL) such that the anterior MTL is thought to support processing of individual items (e.g., item memory and complex object perception), whereas the posterior MTL is thought to support item‐context retrieval (e.g., source memory). Whereas functional imaging studies have provided evidence supporting this anatomical organization, results from structural analyses remain inconclusive. The current study examined the relationship between volume of MTL regions of interest (ROIs), and performance on a source memory task and a fine‐grain complex object perception task, in healthy young adults (mean age = 21.5, range = 18–29). Using a semiautomated procedure, we segmented the parahippocampal and perirhinal cortices (PHC, PRC), posteromedial and anterolateral entorhinal cortices (pmERC, alERC), and posterior and anterior hippocampus (postHC, antHC) on high‐resolution T2‐weighted MRIs. Regional volumes were computed as proportions of intracranial volume, and as posterior–anterior volumetric ratios (PHC:PRC, pmERC:alERC, postHC:antHC). Partial‐least squares regressions were applied to predict source and item memory, and perceptual discrimination accuracy, based on ROI and ratio volumes. In our ROI regressions, we found that postHC volume was positively correlated with a latent factor predicting source memory, and PRC and antHC volumes were negatively correlated to this latent factor. In our ratio regressions, we observed an effect relating the posterior–anterior distribution of gray matter across the MTL with source memory. Our results demonstrate differential associations between anterior and posterior MTL and source memory performance. Findings from this study highlight the importance of considering patterns of structure–behavior associations in the neurobiology of episodic memory.
The function of medial temporal lobe and posterior middle temporal gyrus in forming creative associations
Authors: Zhang Ze , Liu Lulu , Li Yue , Tan Tengteng , Niki Kazuhisa , Luo Jing 
Published: August 2020

AbstractAlthough the function of the hippocampus and adjacent medial temporal lobe (MTL) areas in forming associations is generally recognized, how MTL contributes to form creative associations that could result in novel and appropriate functions or meanings remains unclear. In this study, we compared highly creative combinations (HCCs) of two objects (e.g., that of “lifejacket” and “distress signal device”) that resulted in genuine innovative designs comprising additionally unprecedented functions (the “1 + 1 > 2” effects) with the lowly creative combinations (LCCs, e.g., the combination of “set‐top box” and “jewelry box”) that resulted in nothing more than simple “1 + 1 = 2” effects. The event‐related functional magnetic resonance imaging (fMRI) study found that during the “early binding phase,” when the combinations of the two objects were initially encoded, the right parahippocampus was more intensively activated during the encoding of HCC relative to LCC trials. However, during the “late integration phase,” when participants finally formed a holistic mental representation of new products based on the two‐object combinations, both HCCs and LCCs were found to be associated with significantly increased hippocampal and parahippocampal activation relative to the baseline condition, but at a similar level. In this “late integration phase,” the functional areas appeared to be more intensively activated in HCCs relative to LCCs located in the posterior middle temporal gyrus (pMTG), the area known to mediate category‐related processing. Consistently, our supplementary behavioral study found that, relative to LCCs, HCCs had a higher possibility of resulting in some new conceptual expansions that differed from each of the original two objects that constituted the combinations. These findings indicate that the formation of creative combinations not only require MTL‐based novel association‐formation, but also pMTG‐based novel concept‐expansion.
Dynamic operating efficiency and its determining factors of listed real‐estate companies in China: A hierarchical slack‐based DEA‐OLS approach
Authors: Atta Mills Ebenezer Fiifi Emire , Baafi Mavis Agyapomah , Liu Fangbiao , Zeng Kailin 
Published: August 2020

AbstractThis study uses a dynamic slacks‐based measure (SBM) model in a data envelopment analysis (DEA) framework with surplus reserve and accounts receivable as desirable and undesirable indicators respectively, based on inter‐connectivity between consecutive periods to estimate the operating efficiency of 110 listed Chinese real‐estate companies in the first step analysis. The results show that 35 listed real‐estate companies in China operated on the efficient frontier by maintaining sustainable growth throughout the entire period. The analysis presents the projection of indicators to suggest a feasible solution to improve the inefficient terms. At the second step analysis, using ordinary least square (OLS) estimation, authors find a curve‐linear relationship between real‐estate company size and efficiency to suggest that operating efficiency increases as size also increases due to economies of scale but only up to an optimum point. Profitability and higher education are also identified as the other significant determinants of operating efficiency. The findings of this research present evidence that average efficiency scores vary over time and generally comove with China's economic growth rate and the average stock returns in the real‐estate sector. By providing a new framework for evaluating input, output and carry‐over indicators of real‐estate companies, the results of this study equip real‐estate companies to have an accurate perspective of their operating position and simultaneously provide investors with an avenue to evaluate real‐estate companies' development before any form of investment.
Do determinants of fees differ between Islamic and conventional funds?
Authors: Mehri Meryem , Hassan M. Kabir , Safa M. Fasial , Siraj Ibrahim 
Published: August 2020

AbstractThis paper examines the effects of country conditions on fund manager fees. By using an international sample of 607 funds from 23 countries, the authors show that legal, culture, and political risk have robust effects on fund manager fees. The findings indicate that Islamic and conventional funds in developing countries with weaker legal settings and higher corruption have higher fixed and performance fees. However, performance fees are lower and fixed fees are higher in countries with higher political risk. Overall, Hofstede's cultural values significantly affect the fund fees with robust differential effects between Islamic and conventional funds.