bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic potential of ivermectin as add on treatment in COVID 19: A systematic review and meta-analysis
Authors: Padhy Biswa Mohan , Mohanty Rashmi Ranjan , Das Smita , Meher Bikash Ranjan 
Published: November 2020

The current management of COVID-19 is mostly limited to general supportive care and symptomatic treatment. Ivermectin is a broad-spectrum anti-parasitic drug used widely for the treatment of onchocerciasis and lymphatic filariasis. Apart from its anti-parasitic effect it also exhibits antiviral activity against a number of viruses both in vitro and in vivo. Hence, we conducted this systematic review and meta-analysis to assess the currently available data on the therapeutic potential of ivermectin for the treatment of COVID‐19 as add on therapy. A total of 629 patients were included in the 4 studies and all were COVID-19 RT-PCR positive. Among them, 397 patients received ivermectin along with usual therapy. The random effect model showed the overall pooled OR to be 0.53 (95%CI: 0.29 to0.96) for the primary outcome (all-cause mortality) which was statistically significant (P=0.04). Similarly, the random effect model revealed that adding ivermectin led to significant clinical improvement compared to usual therapy (OR=1.98, 95% CI: 1.11 to 3.53, P=0.02). However, this should be inferred cautiously as the quality of evidence is very low. Currently, many clinical trials are on-going, and definitive evidence for repurposing this drug for COVID-19 patients will emerge only in the future.
Seasonal Influence on Post Thaw Seminal Attributes and Conception Rate from Semen of Jaffarabadi Buffalo Bulls
Authors: Parmar K.H. , Tank P.H. , Kavani F.S. 
Published: November 2020

Background: The quality of the frozen thawed semen is one of the most powerful factor affecting the conception rate in a buffaloes. The season may have its effect on post thaw seminal attributes and fertility. Therefore, current study was aimed to investigate the effect of winter and summer seasons on post thaw seminal attributes and conception rate from semen of Jaffarabadi buffalo bulls.Methods: The study was conducted on four Jaffarabadi breeding bulls, 5-6 years old, to know the post-thaw semen characteristics based on total of 192 semen ejaculates evaluated and cryopreserved over one year period. Result: The mean percentages of post-thaw motility, live sperm, abnormal sperm, HOST reactive sperm, acrosomal integrity and first AI conception rate for semen cryopreserved during winter were 58.85±0.56, 67.06±0.77, 8.62±0.43, 58.52±0.67, 75.22±0.27 and 45.75±0.21, respectively, whereas, corresponding values for semen cryopreserved during summer were 56.35±0.43, 65.62±0.76, 9.08±0.51, 55.43±0.60, 74.29±0.22 and 43.50±0.11. The semen quality of post thawed samples were observed better during winter compared to summer season for artificial insemination with satisfactory first AI conception rate.
Sex Wise Morphometrical Studies on Orbital Cavity and Foramina of Skull of Adult Blue Bull (Boselaphus tragocamelus)
Authors: Sathapathy S. , Dhote B.S. , Singh I. , Mrigesh M. , Joshi S.K. , Biswal S.S. , Sahu S.K. , Ali I. 
Published: November 2020

Background: The Blue bull (Boselaphus tragocamelus) is one of the biggest antelopes in Asia and is widely distributed in both the forests and adjoining villages with enough green grass.Methods: The present study was carried out on the orbital cavity and foramina of skull of six specimens of adult Blue bull (Boselaphus tragocamelus) of either sex. The biometrical parameters were measured by scale, graduated tape and digital Vernier’s caliper.Result: The average left cranio-caudal orbital diameter was found to be 5.7±0.11 cm in female, which was significantly less (p less than 0.05) than that of males, where it was recorded as 5.3±0.08 cm. Similarly, the average left orbital depth was found to be 5.7±0.08 cm in female, which was significantly less (p less than 0.05) than that of males, where it was recorded as 5.3±0.06 cm. The average length of left orbital process of frontal bone was found to be 5.1±0.05 cm in female, which was significantly less (p less than 0.05) than that of males, where it was recorded as 5.3±0.07 cm. The average diameter of left supraorbital foramen was found to be 0.31±0.001 cm in female, which was significantly less (p less than 0.05) than that of males, where it was recorded as 0.7±0.003 cm. Similarly, the average maximum distance between two cranial palatine foramina was found to be 1.8±0.05 cm in female, which was significantly less (p less than 0.05) than that of males, where it was recorded as 3.3±0.12 cm. Conclusion: Most of the biometrical observations on different parameters of orbital cavity and different foramina of skull of Blue bull were having significantly (p less than 0.05) more values in males than females. The present gross and biometrical studies would be useful to the wild life professionals for determination of sex of this animal and solving vetero-legal cases related with this species.
Impact of Probiotic and Zinc on Brush-border Enzyme and Histoenzymatic Profile in the Small Intestine of Pre and Post-weaned Piglets
Authors: Kalita Arup , Talukdar M. , Sarma K. , Kalita P.C. , Gali J.M. , Tamuli S. , Choudhary O.P. , Doley P.J. , Debroy S. , . Keneisenuo 
Published: November 2020

Background: Probiotics and zinc are commonly used and beneficial in pig production. This work aimed to assess the effect of probiotic and zinc on brush-border enzyme activity and histoenzymatic study of the small intestine in pre and post-weaned piglets. Methods: Eighteen LWY piglets were divided equally into control and treatment groups. The piglets were maintained in standard management conditions and were weaned at 28 days of age. The treatment group of piglets fed a mixture of probiotics orally @ 1.25 x 109 CFU/day and zinc @ 2000 ppm/day from birth to 10 days of age. At three different age-groups viz. day 20 (pre-weaning), day 30 (weaning) and day 60 (post-weaning), the animals were sacrificed. For disaccharidase enzyme estimation, the mucosal brush border of the small intestine was scrapped off and the experiment was conducted. For histoenzymatic assay, the small intestine samples were preserved in liquid nitrogen at -196ºC immediately after sacrifice. They were sectioned at 10µm thickness maintained at -20ºC and stained for different histochemical staining. The statistical analysis of the data using the appropriate statistical tests was also conducted. Result: The activity of different brush-border enzymes such as maltase, sucrase and lactase was more in the treatment group of piglets. The activity of different histochemical enzymes such as alkaline phosphatase, acid phosphatase, adenosine tri-phosphatase and non-specific esterase was increased in the treated group of piglets.
KOMUNIKASI PENDIDIKAN MELALUI PELATIHAN KEWIRAUSAHAAN DI WILAYAH TINGGAL MAHASISWA PADA MASA PANDEMI COVID-19
Authors: Setianti Yanti , Subekti Priyo , Permana Rangga Saptya Mohamad , Budiana Heru Ryanto 
Published: November 2020

Kehilangan pekerjaan, menurunnya pendapatan dan berubahnya sistem pembelajaran adalah persoalan yang dihadapi masyarakat pada masa pandemi COVID-19 yang bisa berimbas kepada mereka yang mempunyai anak mahasiswa. Salah satu upaya menumbuhkan kesadaran untuk bertahan ditengah suasana pendemi ini adalah mencoba menumbuhkan jiwa kewirausahaan bagi masyarakat khususnya mahasiswa dengan melaksanakan komunikasi pendidikan melalui pelatihan kewirausahaan sehingga mereka bisa memulai usaha yang bisa menghasilkan pendapatan untuk membantu orang tuanya membiayai uang kuliah dan kehidupan sehari hari. Tujuan dari penelitian ini adalah untuk mengetahui pengetahuan mahasiswa tentang kewirausahaan, keterampilan mahasiswa membuat perencanaan kewirausahaan dan keterampilan mahasiswa melakukan kewirausahaan. Metode yang digunakan dalam penelitian ini adalah deskriptif yaitu memberi gambaran mengenai pengetahuan,perencanaan dan pelaksanaan kewirausahaan oleh mahasiswa di pulau Jawa dan Bali. Hasil penelitian menunjukkan setelah dilakukan kegiatan pelatihan pengetahuan mahasiswa mengenai kewirausahaan menjadi meningkat, dari yang tidak tahu sama sekali mengenai wirausaha menjadi tahu apa yang dimaksud dengan kewirausahaan. Keterampilan mahasiswa dalam merencanakan kewirausaha meningkat, dari yang tidak mengerti sama sekali mengenai perencanaan wirausaha menjadi mengerti dan mempraktikkan perencanaan wirausaha. Keterampilan mahasiswa mengenai pelaksanaan wirausaha meningkat, dari yang tidak pernah membayangkan suatu saat mereka akan bisa wirausaha menjadi terbayangkan bagaimana nantinya kalau mereka jadi pengusaha.
Cryptococcal Osteomyelitis of the Entire Humerus
Authors: Onishi Okihiro , Kida Yoshikazu , Kiba Takashi , Kabuto Yukichi , Minami Masataka , Nishimura Ayako , Konishi Eiichi , Takahashi Kenji 
Published: November 2020

Case:
We describe a case of cryptococcal osteomyelitis in a 70-year-old man who presented with left elbow and shoulder pain. Subsequent imaging indicated osteomyelitis of the entire humerus, and he underwent debridement of the elbow and shoulder. Pathological findings revealed Cryptococcus neoformans infection. Surgical management was followed by a prolonged course of antibiotics.

Conclusion:
Although C. neoformans is rare as the etiology of infection of the entire humerus, orthopaedic surgeons should consider cryptococcosis as a potential cause of infection.
A Needs Assessment for Postgraduate Training in Selected Public Health Disciplines: Evidence from Health Services Organisations in Lusaka, Zambia
Authors: Bulawayo Maio , Silumbwe Adam , Munakampe Margarate Nzala , Mukumbuta Nawa , Musabula Juliet , Chewe Mwimba , Mweemba Chris , Michelo Charles , Hangoma Peter 
Published: November 2020

Abstract
Background: As most low and middle-income countries seek to achieve universal health coverage targets, there is an ever-increasing need to train human resources with the required core skills and competencies. This study reports on a needs assessment conducted among health services organisations (HSOs) to understand postgraduate training needs and service gaps for selected public health disciplines – Health Policy and Systems, Health Economics, and Healthcare Management and Planning – at the University of Zambia. Methods: The study adopted a cross-sectional design, comprising qualitative and quantitative components. Data were collected using semi-structured questionnaires administered to 32 representatives of purposively sampled public and private health service organisations based in Lusaka Zambia. The health services organisations included regulatory authorities, research institutions, government ministries, insurance firms and other cooperating partners. Results: Overall (n=22), more than 68% of the stakeholders reported that they had no employees that were formally trained in the three disciplines. More than 90% of the stakeholders opined that training in these disciplines would be beneficial in providing competencies to strengthen service provision. The horizontal skills mismatch for health economics, and health services management and planning were found to be 93% and 100%, respectively. Among the critical public health training needs were: policy development and analysis, economic evaluation, and strategic management. Conclusions: This study confirms that introducing post-graduate training in the proposed public health disciplines will not only benefit Zambian health services organisations but also help strengthen the health systems in general. For other empirical contexts, the findings imply the need for the introduction of academic programmes which respond to ever-changing public health skills demanded. They should be matched with local priorities and service delivery.
Constructing personal networks in the light of COVID-19 containment measures
Authors: Furfaro Emanuela , Rivellini Giulia , Pelle Elvira , Zaccarin Susanna 
Published: November 2020

Abstract
The policies for containing the spread of SARS-CoV2 virus include a number of measures aimed at reducing physical contacts. In this paper, we explore the potential impact of such containment measures on social relations of both young adults and elderly in Italy. We propose two ego-centered network definitions accounting for physical distances in light of the recent - and maybe future - COVID-19 containment measures: 1) the easy-to-reach network, that represent a nearby possible source of support in case of new lockdown; 2) accustomed-to-reach network, which include proximity and habit to meet in person. The approach used for constructing personal (ego-centered) networks on data from the most recent release of Families and Social Subject Survey allows to bring in the foreground people exposed to relational vulnerability. The analysis of the most vulnerable No alters individuals by age, gender and place of residence reveal that to be single is often associated with a condition of relational vulnerability not only among elder people, but also for young adults. Results also highlight the role of the place of residence.
Isolation and Characterization of Novel Yeasts From Dairy Cattle Rumen for Potential Use as Feed Additives&nbsp;
Authors: Suntara Chanon , Cherdthong Anusorn , Wanapat Metha , Uriyapongson Suthipong , Leelavatcharamas Vichai , Sawaengkaew Jutaporn , Chanjula Pin , Foiklang Suban 
Published: November 2020

Abstract
The aims of this study were to screen and isolate yeast which is producing high biomass and cellulase enzyme from rumen fluid. Two fistulated Thai crossbred Holstein Friesian steers, averaging 350 ± 20 kg body weight, were used. The experiments were designed by 12 × 3 × 3 factorial arrangement in a completely randomized (CRD). Factor A was isolated yeasts (11 difference characteristics) and S. cerevisiae. Factor B was sugarcane molasses (M) concentration (50, 150, and 250 g/L). Factor C was urea (U) concentration (10, 30, and 50 g/L) (experiment 1). To assess biochemical properties, the potential yeast were selected for identified and analyzed. The highest yeast biomass was observed in three yeasts including codes H-KKU20, I-KKU20, and C-KKU20. The highest CMCase activity was observed in yeast code H-KKU20. Identification of isolates H-KKU20 and I-KKU20 revealed that those isolates belonged to Pichia kudriavzevii-KKU20 and Candida tropicalis-KKU20, while C-KKU20 was identified as Galactomyces sp.-KKU20. The P. kudriavzevii-KKU20 and C. tropicalis-KKU20 provided maximum cell growth. The highest ethanol production was observed in S. cerevisiae. The P. kudriavzevii-KKU20 yielded the least reducing sugar. P. kudriavzevii-KKU20 had higher results than the other yeasts in terms of yeast biomass production, cellulase enzyme activity, and cell number. This species may lead to higher production of yeast cell wall than the traditional species in yeast industry (such as S. cerevisiae) or in other applications as ruminant feed additives.
Atomistic wear mechanisms and deformation evolution in polishing
Authors: Fang Te-Hua , Nguyen Van-Thuc 
Published: November 2020

Abstract
Our aim with this study was a new insight into the sub-nanoscale of polishing and provides the atomic view of the material removal and wear mechanisms by carrying out molecule dynamics simulation. We proposed and analyzed a model with a diamond abrasive particle that sliding or rolling on the surface of GaN workpieces. The authors investigated, step by step, the effects of polishing depths, speeds, abrasive sizes, and crystalline orientations on the wear mechanisms and material removal. The wear mechanisms of the sliding motion were adhering, ploughing, and cutting, depending on the depths. While the wear mechanisms of rolling motion are adhering and ploughing. Notably, in both stages of sliding and rolling, there is an existence of a critical point at 5.0 Å depth when we considered the deformation behaviors. Below that critical point, the GaN workpiece will present an elastic deformation. From the aforementioned point, the workpiece would be plastically deformed. Besides, from 10 Å depth, the dislocation began to appear and evolute simultaneously with the development of the maximum shear stress. The sliding motion on the Ga-face could remove a greater number of atoms than that of the N-face. Moreover, direction [1-100] on Ga-face requesting more forces to polish than direction [11-20]. In conclusion, the main achievements that contribute to the field can be summarized as follows: the atomistic wear mechanisms of sliding and rolling motions, material removal, and the role of rolling motion at the sub-nanoscale during the ultrafine flat polishing process.
Characteristics of PCDD/Fs in PM2.5 From Emission Stacks and The Nearby Ambient Air in Taiwan
Authors: Pan Shih Yu , Liou Yi Ting , Chang Moo Been , Chou Charles C.-K. , Ngo Tuan Hung , Chi Kai Hsien 
Published: November 2020

Abstract
This study aimed to find the characteristics of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in fine particulate matter from different stationary emission sources (coal-fired boiler, CFB; municipal waste incinerator, MWI; electric arc furnace, EAF) in Taiwan and the relationship between PM2.5 and PM2.5-bound PCDD/Fs with Taiwanese mortality risk. PM2.5 was quantified using gravimetry and corresponding chemical analyses were done for PM2.5-bound chemicals. Mortality risks of PM2.5 exposure and PCDD/Fs exposure were calculated using Poisson regression. The highest concentration of PM2.5 (0.53±0.39 mg/Nm3) and PCDD/Fs (0.206±0.107 ng I-TEQ/Nm3) was found in CFB and EAF, respectively. Higher proportions of PCDDs over PCDFs were observed in the flue gases of CFB and MWI whereas it was reversed in EAF. For ambient air, PCDD/F congeners around the stationary sources were dominated by PCDFs in vapor phase. Positive matrix factorization (PMF) analysis found that the sources of atmosphere PCDD/Fs were 14.6% from EAF (r=0.81), 52.6% from CFB (r=0.74), 18.0% from traffic (r=0.85) and 14.8% from MWI (r=0.76). For the dioxin congener distribution, PCDDs were dominant in flue gases of CFB and MWI, PCDFs were dominant in EAF. It may be attributed to the different formation mechanisms among wastes incineration, steel-making, and coal-burning processes.
Biocompatible MIP-202 Zr-MOF Tunable Sorbent for Cost-Effective Decontamination of Anionic and Cationic Pollutants From Waste Solutions
Authors: Diab Kamal , Salama Eslam , Hassan Hassan Shokry , El-moneim Ahmed Abd , Elkady Marwa 
Published: November 2020

Abstract
This reported work aims to fabricate an eco-friendly Zr bio-based MOF and assessment its adsorption efficiency towards the cationic and anionic dye pollutants including methylene blue (MB) and direct red 81 (DR-81), respectively. Also, its adsorption tendency for the highly toxic heavy metal of hexavalent chromium (Cr(VI)) was compared with dyes. The adsorption performance of bio-MOF showed that the maximum monolayer adsorption capacities were recorded as 79.799 mg/g for MB, 36.071 mg/g for DR-81, and 19.012 mg/g for Cr(VI). Meanwhile, the optimum dosage of as-synthesized MIP-202 bio-MOF was 0.5, 1, and 2 g L-1 for MB, DR-81, and Cr(VI), respectively. Thermodynamic analysis demonstrated the spontaneous, thermodynamically, and endothermic nature of the decontamination processes onto the fabricated Zr bio-based MOF. The adsorption data were fitted by Langmuir isotherm model compared with Freundlich and Temkin models for all studied water pollutants. Pseudo-second-order kinetic model was a ﬁt model for description of the adsorption kinetics of the different cationic and anionic pollutants onto Zr bio-based MOF. These outcomes indicated that Zr bio-based MOF has potential application for adsorption of different types of industrial water pollutants including cationic and anionic dyes and heavy metals.
Safety and Effectiveness of Kidney Transplantation Using a Donation-After-Brain-Death Donor With Acute Kidney Injury: A Retrospective Cohort Study
Authors: Kim Kyeong Deok , Lee Kyo Won , Kim Sang Jin , Lee Okjoo , Lim Manuel , Jeong Eun Sung , Kwon Jieun , Yang Jaehun , Oh Jongwook , Park Jae Berm 
Published: November 2020

Abstract
The use of kidneys from donation-after-brain-death (DBD) donors with acute kidney injury (AKI) is a strategy to expand the donor pool. The aim of this study was to evaluate how kidney transplantation (KT) from a donor with AKI affects long-term graft survival in various situations. All patients who underwent KT from DBD donors between June 2003 and April 2016 were retrospectively reviewed. The KDIGO (Kidney Disease: Improving Global Outcomes) criteria were used to classify donor AKI. The cohort included 376 donors (no AKI group, n = 117 [31.1%]; AKI group n = 259 [68.9%]). Death-censored graft survival was similar according to the presence of AKI, AKI severity, and the AKI trend (p = 0.929, p = 0.077, and p = 0.658, respectively). Patients whose donors had AKI who received using low dose (1.5 mg/kg for three days) rabbit anti-thymocyte globulin (r-ATG) as the induction agent had significantly superior death-censored graft survival compared with patients in that group who received basiliximab (p = 0.039). AKI in DBD donors did not affect long-term death-censored graft survival. Low-dose r-ATG may be considered as an induction immunosuppression in recipients receiving kidneys with AKI because it showed better graft survival than basiliximab.