bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wavelet Transform based Multiple Image Watermarking Technique
Authors: Nanmaran R , Nagarajan S , Sindhuja R , Charan Garudadri Venkata Sree , Pokala Venkata Sai Kumar , Srimathi S , Gulothungan G , Vickram A. S , Thanigaivel S 
Published: December 2020

Abstract
In satellite communication the information’s like frequency, Polarization, Data format, Timing information are need to be protected for secure communication. Digital watermarking is the technique which provides secure way of communication in which the secret information or watermark can be transmitted safely. Wavelet Transform is playing an increasingly important role in watermarking due to its good spatial-frequency characteristics, and its wide applications in the image and video coding standards. In this work a novel Hybrid Steerable Pyramid with Discrete Wavelet Transform (SP+DWT) based multiple watermarking is attempted for colour images. In order to increase the robustness of the algorithm Arnold transform and Fibonacci transform based image scrambler is applied to watermarks before embedding in to cover image. The performance of the proposed scheme is validated for various attacks, such as Gaussian noise, Salt & Pepper Noise, Rotation, Translation and Speckle Noise. The proposed method is withstood for all the noise attacks and the performance of the proposed algorithm is measured using Peak Signal to Noise Ratio (PSNR), Normalized Correlation (NC) and Similarity Measure (SM). Pearson Independent component Analysis (ICA) is applied at the receiving end to extract watermarks from the input image. To analyse the inclusion of image scrambler the results of proposed algorithm is compared with same algorithm without image scrambler applied. The performance of proposed technique is also compared with other wavelet transforms like Discrete Wavelet Transform (DWT), Wavelet Packet Transform (WPT) and Integer Wavelet Transform (IWT). Simulation results such as PSNR,NC,SM shows that hybrid SP+DWT based watermarking technique and extraction using Pearson ICA results in high imperceptible, better security and robustness, when compared to DWT, WPT and IWT based watermarking and extraction using Pearson ICA.
Risk of conversion to open surgery during robotic and laparoscopic pancreatoduodenectomy and effect on outcomes: international propensity score-matched comparison study
Authors: Lof S , Vissers F L , Klompmaker S , Berti S , Boggi U , Coratti A , Dokmak S , Fara R , Festen S , D’Hondt M , Khatkov I , Lips D , Luyer M , Manzoni A , Rosso E , Saint-Marc O , Besselink M G , Abu Hilal M ,   the European consortium on Minimally Invasive Pancreatic Surgery (E-MIPS)
Published: December 2020

Abstract

Background
Minimally invasive pancreatoduodenectomy (MIPD) is increasingly being performed because of perceived patient benefits. Whether conversion of MIPD to open pancreatoduodenectomy worsens outcome, and which risk factors are associated with conversion, is unclear.

Methods
This was a post hoc analysis of a European multicentre retrospective cohort study of patients undergoing MIPD (2012–2017) in ten medium-volume (10–19 MIPDs annually) and four high-volume (at least 20 MIPDs annually) centres. Propensity score matching (1 : 1) was used to compare outcomes of converted and non-converted MIPD procedures. Multivariable logistic regression analysis was performed to identify risk factors for conversion, with results presented as odds ratios (ORs) with 95 per cent confidence intervals (c.i).

Results
Overall, 65 of 709 MIPDs were converted (9.2 per cent) and the overall 30-day mortality rate was 3.8 per cent. Risk factors for conversion were tumour size larger than 40 mm (OR 2.7, 95 per cent c.i.1.0 to 6.8; P = 0.041), pancreatobiliary tumours (OR 2.2, 1.0 to 4.8; P = 0.039), age at least 75 years (OR 2.0, 1.0 to 4.1; P = 0.043), and laparoscopic pancreatoduodenectomy (OR 5.2, 2.5 to 10.7; P &lt; 0.001). Medium-volume centres had a higher risk of conversion than high-volume centres (15.2 versus 4.1 per cent, P &lt; 0.001; OR 4.1, 2.3 to 7.4, P &lt; 0.001). After propensity score matching (56 converted MIPDs and 56 completed MIPDs) including risk factors, rates of complications with a Clavien–Dindo grade of III or higher (32 versus 34 per cent; P = 0.841) and 30-day mortality (12 versus 6 per cent; P = 0.274) did not differ between converted and non-converted MIPDs.

Conclusion
Risk factors for conversion during MIPD include age, large tumour size, tumour location, laparoscopic approach, and surgery in medium-volume centres. Although conversion during MIPD itself was not associated with worse outcomes, the outcome in these patients was poor in general which should be taken into account during patient selection for MIPD.
Neurodevelopmental Outcomes of Children Following In Utero Exposure to Zika in Nicaragua
Authors: Stringer Elizabeth M , Martinez Evelin , Blette Bryan , Toval Ruiz Christian Eduardo , Boivin Michael , Zepeda Omar , Stringer Jeffrey S A , Morales Marlen , Ortiz-Pujols Shiara , Familiar Itziar , Collins Matthew , Chavarria Meylin , Goldman Barbara , Bowman Natalie , de Silva Aravinda , Westreich Daniel , Hudgens Michael , Becker-Dreps Sylvia , Bucardo Filemon 
Published: December 2020

Abstract

Background
Neurodevelopmental outcomes of asymptomatic children exposed to Zika virus (ZIKV) in utero are not well characterized.

Methods
We prospectively followed 129 newborns without evidence of congenital Zika syndrome (CZS) up to 24 months of age. Participants were classified as ZIKV exposed or ZIKV unexposed. The Mullen Scales of Early Learning (MSEL) was administered in the participants’ homes at 6, 12, 15, 18, 21, and 24 months of age by trained psychologists. Sociodemographic data, medical history, and infant anthropometry at birth were collected at each home visit. Our primary outcome was the Mullen Early Learning Composite Score (ECL) at 24 months of age between our 2 exposure groups. Secondary outcomes were differences in MSEL subscales over time and at 24 months.

Results
Of 129 infants in whom exposure status could be ascertained, 32 (24.8%) met criteria for in utero ZIKV exposure and 97 (75.2%) did not. There were no differences in maternal age, maternal educational attainment, birthweight, or gestational age at birth between the 2 exposure groups. The adjusted means and standard errors (SEs) for the ELC score between the ZIKV-exposed children compared to ZIKV-unexposed children were 91.4 (SE, 3.1) vs 96.8 (SE, 2.4) at 12 months and 93.3 (SE, 2.9) vs 95.9 (SE, 2.3) at 24 months. In a longitudinal mixed model, infants born to mothers with an incident ZIKV infection (P = .01) and low-birthweight infants (&lt;2500 g) (P = .006) had lower composite ECL scores.

Conclusions
In this prospective cohort of children without CZS, children with in utero ZIKV exposure had lower neurocognitive scores at 24 months.
New Division Property Propagation Table: Applications to Block Ciphers with Large S-boxes
Authors: Hu Xichao , Li Yongqiang , Jiao Lin , Wang Mingsheng 
Published: December 2020

Abstract
The division property method is a technique for automatic searching integral distinguishers on block ciphers. Previous methods only use word-based division property to search integral distinguishers for block ciphers with large S-boxes. Since using bit-based division property may find longer integral distinguishers than word-based division property, we propose a method to automatically search the integral distinguishers based on bit-based division property for block ciphers with large S-boxes. To achieve this goal, we propose a new division property propagation table for S-boxes. Theoretically, we prove that using both the new table and the traditional method to describe the bit-based division property propagation rule of S-box will lead to the same integral distinguishers. Technically, we design a mixed-integer linear programming-based tool to search the integral distinguisher based on the new table, which helps to search new integral distinguishers for block ciphers with large S-boxes efficiently. As a result, we apply our tool to derive new integral distinguishers and get the tight bound on the rounds that no integral distinguishers exist for ICEBERG, KHAZAD, Camellia, CS-Cipher, ITUbee and SMS4. Besides, to show the availability of our integral distinguishers, we form the present best five-round and the first six-round integral attack for ICEBERG as an example.
Piracy: A Treasure Box of Otherness
Authors: Zar Mickey 
Published: December 2020

Abstract
This article explores the connection between maritime and digital piracy, and pursues the thought that the common moniker is more than a rhetorical flourish. Golden Age maritime piracy (1650–1730) and today’s piracy in cyberspace are by no means identical; there is no one ideal form of piracy. And yet, pirates of the literal and virtual high seas share a crucial feature: their social role as others. Piracy itself is a social function; its content is otherness. Dominant accounts of piracy note its character as a mode of resistance, but frame that resistance as either economic or political. Neither of these explanations of piracy’s resistance is sufficient on its own. The comparison of Golden Age maritime piracy with current digital piracy is telling, because what these two modes of piracy have in common is the way they highlight the relationship between capital and the state system. In other words, piracy’s political attack is not simply an assault on the idea of sovereignty, but rather a more specific critique of the way the system of sovereign states advances the interests of capital. The legal treatment of piracy, making it the pillar of universal jurisdiction, highlights the particular threat that piracy presents to the world order: the crime is political because it is an affront to the economic-political alliance that is capitalism, old or new.
Glioma-Derived TSP2 Promotes Excitatory Synapse Formation and Results in Hyperexcitability in the Peritumoral Cortex of Glioma
Authors: Wang Yao-Hui , Huang Tian-Lan , Chen Xin , Yu Si-Xun , Li Wei , Chen Tao , Li Yang , Kuang Yong-Qin , Shu Hai-Feng 
Published: December 2020

Abstract
Seizures are common in patients with glioma, especially low-grade glioma (LGG). However, the epileptogenic mechanisms are poorly understood. Recent evidence has indicated that abnormal excitatory synaptogenesis plays an important role in epileptogenesis. The thrombospondin (TSP) family is a key regulator of synaptogenesis. Thus, this study aimed to elucidate the role of TSP2 in epileptogenesis in glioma-related epilepsy. The expression of TSP2 was increased in tumor tissue specimens from LGG patients, and this increase may have contributed to an increase in the density of spines and excitatory synapses in the peritumoral area. A glioma cell-implanted rat model was established by stereotactic implantation of wild-type TSP2-expressing, TSP2-overexpressing or TSP2-knockout C6 cells into the neocortex. Similarly, an increase in the density of excitatory synapses was also observed in the peritumoral area of the implanted tumor. In addition, epileptiform discharges occurred in the peritumoral cortex and were positively correlated with the TSP2 level in glioma tissues. Moreover, α2δ1/Rac1 signaling was enhanced in the peritumoral region, and treatment with the α2δ1 antagonist gabapentin inhibited epileptiform discharges in the peritumoral cortex. In conclusion, glioma-derived TSP2 promotes excitatory synapse formation, probably via the α2δ1/Rac1 signaling pathway, resulting in hyperexcitability in the peritumoral cortical networks, which may provide new insight into the epileptogenic mechanisms underlying glioma-related epilepsy.
Mechanical behavior of a circular dielectric elastomer membrane under out-of-plane deformation
Authors: Zhang J W , Chen J W , Ren Z Q 
Published: December 2020

Abstract
The mechanical behavior of a circular dielectric elastomer membrane (DEM) under the contact of a rigid ball is studied in this paper. The out-of-plane deformation of the DEM is unfolded to an equivalent in-plane deformation, and the mechanical behavior is further studied through the Helmholtz free energy theory and the Gent model. The theoretical results obtained from the proposed analysis approach are validated through the out-of-plane deformation experiments, and the influence of the DEM's thickness on the mechanical behavior is revealed and explained. Furthermore, the influences of some key dimensional, dynamical and electrical parameters on the DEM's mechanical behavior are investigated and discussed. The research results are helpful for the system analysis of dielectric elastomer actuators and dielectric elastomer generators with out-of-plane deformations.
The Self in the Spectrum: A Meta-analysis of the Evidence Linking Basic Self-Disorders and Schizophrenia
Authors: Raballo Andrea , Poletti Michele , Preti Antonio , Parnas Josef 
Published: December 2020

Abstract
Disturbed self-experience has been reported as a characteristic feature of schizophrenia since the first formulation of its diagnostic concept; however, only in the last 2 decades an explicit notion of basic Self-disturbance, or Self-Disorders (SD), has emerged as target for a systematic research program. We conducted systematic searches in bibliographical databases to identify cross-sectional studies that explored SD across different diagnostic groups and explored diagnostic ascription within or outside schizophrenia spectrum disorders (SSD) as main outcome. Data were pooled using fixed- and random-effects meta-analysis models. Heterogeneity was assessed using stratified meta-analyses and meta-regression. Of 218 identified studies, 32 were included in the systematic review and 27 in the meta-analysis. Patients diagnosed with SSD scored higher on measures of SD than healthy controls (HC) (Hedges’ g = 1.8; 95% CI = 1.5 to 2.0), individuals diagnosed with other mental illness (OMI) (1.9; 1.6 to 2.2), bipolar or affective disorders (1.8; 1.4 to 2.2), and clinical high risk for psychosis (CHR) (1.6; 0.9 to 2.4). Patients with schizotypy or schizotypal personality disorder scored higher on measures of SD than OMI (1.5; 1.3 to 1.8) and HC (1.4; 1.1 to 1.7). Patients with first-episode psychosis scored higher on measures of SD than HC (2.5; 2.1 to 2.9) and OMI (1.6; 1.2 to 2.1). Subjects at CHR scored higher on measures of SD than HC (2.0; 1.7 to 2.2) and OMI (19; 1.6 to 2.2). Overall, heterogeneity ranged from negligible to high, especially in comparisons of the target group with OMI, probably as a reflection of the immanent diagnostic heterogeneity of this group. The findings suggest that SD selectively aggregate within schizophrenia spectrum disorders as compared to other mental disorders and that they could be a central phenotypic marker of vulnerability to schizophrenia across the different shades of severity of its spectrum of disorders.
Ethylene response factors regulate expression of HbSUT3, the sucrose influx carrier in laticifers of Hevea brasiliensis
Authors: Zhang Yi , Xin Lusheng , Pirrello Julien , Fang Yongjun , Yang Jianghua , Qi Jiyan , Montoro Pascal , Tang Chaorong 
Published: December 2020

Abstract
Natural rubber is an important industrial raw material and is commercially produced by rubber trees (Hevea brasiliensis). The sucrose transporter HbSUT3 plays an essential role in rubber production. Its expression in latex (cytoplasm of rubber-producing laticifers) is induced by bark treatment with Ethrel, an ethylene releaser, and the inducing effect correlates well with Ethrel-stimulated rubber yield increase. However, the mechanisms of ethylene induction on HbSUT3 expression are not known. Here, five Ethylene Response Factor (ERF) genes were identified from the cDNA library of Hevea latex by yeast one-hybrid screening with the promoter of HbSUT3 gene as bait. As revealed in a tobacco (Nicotiana tabacum) protoplast transient expression system, these HbERFs were mainly localized in the nucleus and four of them exhibited apparent transactivation activity. Of the five HbERF genes, HbERF-IXc4 was the most frequently screened in yeast one-hybrid, accounting for 65% of the ERF clones obtained. Moreover, among the five HbERFs, HbERF-IXc4 showed the strongest transactivation capacity when expressed in tobacco protoplast, the highest transcript abundance in latex and a close expressional correlation with its target gene, HbSUT3, in response to the Ethrel treatment. Taken together, our results indicate that ERFs, especially HbERF-IXc4, are critically involved in the activation of HbSUT3 expression in latex after Ethrel treatment on Hevea bark, and thus the stimulated latex yield.
Detection of Changuinola virus (Reoviridae: Orbivirus) in field-caught sand flies in southern Thailand
Authors: Phumee Atchara , Wacharapluesadee Supaporn , Petcharat Sininat , Tawatsin Apiwat , Thavara Usavadee , Siriyasatien Padet 
Published: December 2020

Abstract

Background
Phlebotomine sand flies are vectors for several pathogenic bacteria, parasites and viruses that have significant impacts on public health. Sand fly-associated viruses that cause diseases in humans and animals have recently received more attention. This study aimed to detect pathogenic viruses belonging to the Orbivirus genus, Phlebovirus genus, Flavivirus genus and family Rhabdoviridae in several field-caught sand fly species in southern Thailand.

Methods
Sand flies were collected in southern Thailand using CDC light traps. Each sample was processed individually for virus screening using RT-PCR and sequencing.

Results
Seven out of 60 sand fly samples (two samples of Idiophlebotomus spp., three of Phlebotomus papatasi and two of Sergentomyia khawi) were positive for the Orbivirus genus, which is closely related to Changuinola virus (CGLV). Phlebovirus genus, Flavivirus genus and family Rhabdoviridae were negative in all samples.

Conclusions
CGLV causes Changuinola virus disease or Changuinola fever, a febrile illness in Central and South America. The virus has never been reported in Thailand. This study is the first report of the detection of CGLV in sand flies from Thailand. An extensive study of sand flies from other regions of the country and the associations between sand flies, viruses and vertebrate hosts in Thailand should be undertaken.
Use of a Clinic-Based Skin Cancer Prevention Bundle to Promote Sun-Protective Behaviors in Patients at Moderate to High Risk for Skin Cancer
Authors: Petitt Elizabeth K. , Taylor Richard A. , Yu Xiaoying 
Published: December 2020

ABSTRACT

Background
Skin cancer is the most common type of cancer in the United States, and one in five Americans will develop a skin cancer at least once during their lifetime (U.S. Cancer Statistics Working Group, 2016). Analysis of current skin cancer prevention practices in a large academic university dermatology clinic revealed a lack of skin cancer risk stratification, targeted prevention messaging, and assessment of sun-protective behavior (SPB) use. An improvement project was initiated to evaluate the impact of a skin cancer prevention bundle (SCPB) on SPB use and sunburn frequency over a 2-month period.

Methods
Adult clinic patients 20–65 years old, at a moderate to high risk based on Brief Skin Cancer Risk Assessment Tool scores, received an SCPB consisting of personalized Brief Skin Cancer Risk Assessment Tool risk feedback, American Academy of Dermatology skin cancer prevention recommendations, and a brief American Academy of Dermatology skin cancer prevention video. A Sun Habits Survey and an assessment of perceived skin cancer risk were performed preintervention and postintervention.

Results
Thirty-eight participants (92.7%) completed the project. Outcome measures showing significant difference postintervention included Sun Protection Habits Index summary scores (p < .0001), sunburn frequency (p < .0001), and lifetime perceived risk of skin cancer (p = .007). Individual SPB habits of limiting midday ultraviolet exposure (p = .0004) and frequency of hat use (p = .01) also showed significant increases postintervention.

Conclusions and Implications
Use of the clinic-based SCPB improved SPB use and reduced sunburn frequency. The SCPB is being considered for clinic-wide implementation based on the findings. Further study with a larger number of participants and ongoing postclinic implementation evaluation is recommended to confirm results and fully assess the potential of the SCPB to improve patient outcomes and reduce skin cancer risk.
Sternal Precautions and Prone Positioning of Infants Following Median Sternotomy: A Nationwide Survey
Authors: Clifton Amanda , Cruz Giselle , Patel Yesha , Cahalin Lawrence P. , Moore James G. 
Published: December 2020

Purpose:
To describe current practice of pediatric sternal precautions (PSPs) and prone positioning restrictions (PPRs) in infants after median sternotomy.

Methods:
A Web-based survey with 21 questions was developed on the basis of a review of current literature and expert consultation. Snowball sampling resulted in 68 participants well represented by profession throughout the United States.

Results:
Approximately 80% of participants reported having institutional protocols for PSPs. Most common reported PSPs were no lifting at the axillae and no pulling of arms to achieve sitting. PSPs also included PPRs. The opinions of participants supported no PPRs or modified PPRs compared with strict PPRs.

Conclusions:
Types of PPRs varied across participants, with the majority of participants in favor of modified PPRs while PSPs were less varied. Research is needed to examine the effects of PSPs and PPRs in infants post–median sternotomy.
Basic Motor Skills of Children With Down Syndrome: Creating a Motor Growth Curve
Authors: Lauteslager Peter E. M. , Volman M(Chiel). J. M. , Lauteslager Timo , Van den Heuvel Marieke E. , Jongerling Joran , Klugkist Irene G. 
Published: December 2020

Purpose:
To create a motor growth curve based on the Test of Basic Motor Skills for Children with Down Syndrome (BMS) and estimate the age of achieving BMS milestones.

Methods:
A multilevel exponential model was applied to create a motor growth curve based on BMS data from 119 children with Down syndrome (DS) aged 2 months to 5 years. Logistic regression was applied to estimate the 50% probability of achieving BMS milestones.

Results:
The BMS growth curve had the largest increase during infancy with smaller increases as children approached the predicted maximum score. The age at which children with DS have a 50% probability of achieving the milestone sitting was 22 months, for crawling 25 months, and for walking 38 months.

Conclusions:
The creation of a BMS growth curve provides a standardization of the gross motor development of children with DS. Physical therapists then may monitor a child's individual progress and improve clinical decisions.