bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decision Support Capabilities of Telemedicine in Emergency Prehospital Care: Systematic Review
Authors: Kim Yesul , Groombridge Christopher , Romero Lorena , Clare Steven , Fitzgerald Mark Christopher 
Published: October 2020

BackgroundTelemedicine offers a unique opportunity to improve coordination and administration for urgent patient care remotely. In an emergency setting, it has been used to support first responders by providing telephone or video consultation with specialists at hospitals and through the exchange of prehospital patient information. This technological solution is evolving rapidly, yet there is a concern that it is being implemented without a demonstrated clinical need and effectiveness as well as without a thorough economic evaluation.ObjectiveOur objective is to systematically review whether the clinical outcomes achieved, as reported in the literature, favor telemedicine decision support for medical interventions during prehospital care.MethodsThis systematic review included peer-reviewed journal articles. Searches of 7 databases and relevant reviews were conducted. Eligibility criteria consisted of studies that covered telemedicine as data- and information-sharing and two-way teleconsultation platforms, with the objective of supporting medical decisions (eg, diagnosis, treatment, and receiving hospital decision) in a prehospital emergency setting. Simulation studies and studies that included pediatric populations were excluded. The procedures in this review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. The Risk Of Bias In Non-randomised Studies–of Interventions (ROBINS-I) tool was used for the assessment of risk of bias. The results were synthesized based on predefined aspects of medical decisions that are made in a prehospital setting, which include diagnostic decision support, receiving facility decisions, and medical directions for treatment. All data extractions were done by at least two reviewers independently.ResultsOut of 42 full-text reviews, 7 were found eligible. Diagnostic support and medical direction and decision for treatments were often reported. A key finding of this review was the high agreement between prehospital diagnoses via telemedicine and final in-hospital diagnoses, as supported by quantitative evidence. However, a majority of the articles described the clinical value of having access to remote experts without robust quantitative data. Most telemedicine solutions were evaluated within a feasibility or short-term preliminary study. In general, the results were positive for telemedicine use; however, biases, due to preintervention confounding factors and a lack of documentation on quality assurance and protocol for telemedicine activation, make it difficult to determine the direct effect on patient outcomes.ConclusionsThe information-sharing capacity of telemedicine enables access to remote experts to support medical decision making on scene or in prolonged field care. The influence of human and technology factors on patient care is poorly understood and documented.
An Application of Machine Learning to Etiological Diagnosis of Secondary Hypertension: Retrospective Study Using Electronic Medical Records
Authors: Diao Xiaolin , Huo Yanni , Yan Zhanzheng , Wang Haibin , Yuan Jing , Wang Yuxin , Cai Jun , Zhao Wei 
Published: October 2020

Background
Secondary hypertension is a kind of hypertension with a definite etiology and may be cured. Patients with suspected secondary hypertension can benefit from timely detection and treatment and, conversely, will have a higher risk of morbidity and mortality than those with primary hypertension.

Objective
The aim of this study was to develop and validate machine learning (ML) prediction models of common etiologies in patients with suspected secondary hypertension.

Methods
The analyzed data set was retrospectively extracted from electronic medical records of patients discharged from Fuwai Hospital between January 1, 2016, and June 30, 2019. A total of 7532 unique patients were included and divided into 2 data sets by time: 6302 patients in 2016-2018 as the training data set for model building and 1230 patients in 2019 as the validation data set for further evaluation. Extreme Gradient Boosting (XGBoost) was adopted to develop 5 models to predict 4 etiologies of secondary hypertension and occurrence of any of them (named as composite outcome), including renovascular hypertension (RVH), primary aldosteronism (PA), thyroid dysfunction, and aortic stenosis. Both univariate logistic analysis and Gini Impurity were used for feature selection. Grid search and 10-fold cross-validation were used to select the optimal hyperparameters for each model.

Results
Validation of the composite outcome prediction model showed good performance with an area under the receiver-operating characteristic curve (AUC) of 0.924 in the validation data set, while the 4 prediction models of RVH, PA, thyroid dysfunction, and aortic stenosis achieved AUC of 0.938, 0.965, 0.959, and 0.946, respectively, in the validation data set. A total of 79 clinical indicators were identified in all and finally used in our prediction models. The result of subgroup analysis on the composite outcome prediction model demonstrated high discrimination with AUCs all higher than 0.890 among all age groups of adults.

Conclusions
The ML prediction models in this study showed good performance in detecting 4 etiologies of patients with suspected secondary hypertension; thus, they may potentially facilitate clinical diagnosis decision making of secondary hypertension in an intelligent way.
Facebook Support Groups for Rare Pediatric Diseases: Quantitative Analysis
Authors: Titgemeyer Sarah Catrin , Schaaf Christian Patrick 
Published: October 2020

Background
Loneliness, social isolation, and feeling disconnected from society are commonly experienced by parents of children with rare diseases and are, among others, important reasons for special supportive care needs. Social networking platforms are increasingly used for health communication, information exchange, and support. In the field of rare pediatric diseases, qualitative studies have shown that Facebook online support groups are utilized by and beneficial for persons affected by rare pediatric diseases. Nonetheless, the extent of this usage has not been investigated.

Objective
This study aims to provide a comprehensive quantitative analysis of the extent of Facebook usage as a tool for rare pediatric disease support groups and to explore factors that influence a disease’s representation on Facebook. These results potentially offer important insights for future public health initiatives and give direction to further research that can give much needed support to parents of children with rare diseases.

Methods
We determined rare pediatric diseases using the inventory of the online portal Orphanet. Facebook support groups were identified by searching 5 synonymous disease descriptions using the group category search bar. Disease- and group-describing parameters were statistically analyzed using standard descriptive statistical methods.

Results
6398 Facebook support groups, representing 826 diseases (19.5% of all searched diseases), were found. 69% are private groups. Group type, size, activity (sum of posts, comments, and reactions calculated by Facebook), new memberships, and language varied largely between groups (member count: minimum 1, maximum 23,414; activity last 30 days: minimum 0, maximum 3606). The highest percentage of awareness and information groups was found for teratogenic diseases (18/68, 26%). The odds of finding a Facebook group increased according to the level of information available about the disease: known prevalence (odds ratio [OR] 3.98, 95% CI 3.39-4.66, P<.001), known disease type (OR 3.15, 95% CI 2.70-3.68, P<.001), and known inheritance mode (OR 2.06, 95% CI 1.68-2.52, P<.001) were all associated with higher odds of finding a Facebook group, as was dominant compared to nondominant inheritance (OR 2.05, 95% CI 1.74-3.42, P<.001). The number of groups per disease increased with higher prevalence.

Conclusions
Facebook is widely used as a tool for support groups for rare pediatric diseases and continues to be relevant. Two-thirds of the groups are private groups, indicating group participants’ need for privacy, which should be further explored. The advantages and limitations of Facebook as a tool for support groups in the field of rare diseases should be further investigated as it will allow health professionals to use Facebook more meaningfully in their counseling and guidance of affected individuals and their family members.
Consumer-Guided Development of an Engagement-Facilitation Intervention for Increasing Uptake and Adherence for Self-Guided Web-Based Mental Health Programs: Focus Groups and Online Evaluation Survey
Authors: Gulliver Amelia , Calear Alison L , Sunderland Matthew , Kay-Lambkin Frances , Farrer Louise M , Banfield Michelle , Batterham Philip J 
Published: October 2020

Background
Self-guided web-based mental health programs are effective in treating and preventing mental health problems. However, current engagement with these programs in the community is suboptimal, and there is limited evidence indicating how to increase the use of existing evidence-based programs.

Objective
This study aims to investigate the views of people with lived experience of depression and anxiety on factors influencing their engagement with self-guided web-based mental health (e–mental health) programs and to use these perspectives to develop an engagement-facilitation intervention (EFI) to increase engagement (defined as both uptake and adherence) with these programs.

Methods
A total of 24 community members (female=21; male=3) with lived experience of depression and anxiety or depression or anxiety alone participated in 1 of 4 focus groups discussing the factors influencing their engagement with self-guided e–mental health programs and the appearance, delivery mode, and functionality of content for the proposed EFI. A subsequent evaluation survey of the focus group participants (n=14) was conducted to evaluate the resultant draft EFI. Data were thematically analyzed using both inductive and deductive qualitative methods.

Results
Participants suggested that the critical component of an EFI was information that would challenge personal barriers to engagement, including receiving personalized symptom feedback, information regarding the program’s content or effectiveness and data security, and normalization of using e–mental health programs (eg, testimonials). Reminders, rewards, feedback about progress, and coaching were all mentioned as facilitating adherence.

Conclusions
EFIs have the potential to improve community uptake of e–mental health programs. They should focus on providing information on the content and effectiveness of e–mental health programs and normalizing their use. Given that the sample comprised predominantly young females, this study may not be generalizable to other population groups. There is a strong value in involving people with a lived experience in the design and development of EFIs to maximize their effectiveness.
Study of Physicochemical Characteristics of Kaolin from Belitung Regency
Authors: Pasi Nurul Izzah , Bratadireja Marline Abdassah , Chaerunnisa Anis Yohana 
Published: October 2020

Kaolin is one of the abundant clay minerals on earth which has been widely used in various industries. kaolin as a raw material in drugs manufacturing must comply several requirements in Pharmacopoeia such as not exceeding the heavy metal content limits. In this study the analysis of heavy metal content (Pb, Sn, and As) was carried out on natural kaolin obtained from 3 different locations in Belitung regency. Testing of the brightness and particle size is also carried out to increase the value of kaolin as a pharmaceutical excipient. The highest recovery from kaolin was obtained in sample 3 which was 67.78%, while kaolin 1 and 2 which was 66.54, and 64.20%. Based on the results of heavy metal testing it is known that kaolin 1, 2, and 3 have a Pb content of 55.2, 0.0458 and 44.0 ppm, and As content of 1.05, 78.3, and 0.761 ppm. Whereas the Sn mean metal is only found in kaolin 2 which is 0.0034. White degree test results show that kaolin 1, 2 and 3 have a high brightness, namely 92.94%, 93.00%, 91.16%. From the results of particle size testing shows that all kaolin samples have size <2 μm.Keywords: Characterization of Minerals, Heavy Metals, Kaolin
Bednar Tumor – a Case Report
Authors: Cekić Slađana , Jović Andrija , Popović Danijela , Zlatanović Zorana , Vidović Nataša , Kocić Hristina , Tiodorović Danica 
Published: October 2020

Abstract
Bednar tumor is a rare pigmented type of the dermatofibrosarcoma protuberans characterized histologically by the coexistence of two distinct cell populations, including spindle-shaped cells and melanin-containing dendritic cells. We report dermoscopic features of Bednar tumor observed in a 54-year-old female patient. The dermoscopy of Bednar tumor revealed a multicomponent pattern composed of a homogeneous blue-gray pigmentation with shiny white lines, structureless light-brown pigmented areas and a peripheral pigment network. The dermoscopic features observed in the present case are consistent with reported dermoscopic descriptions of Bednar tumor. Although dermoscopy may be suggestive of the diagnosis of Bednar tumor, pathohistological examination remains a gold standard for diagnosis.
Adriaan Hulshoff’s Curaçao: An Analysis of the Novel Dorstig paradijs (1949)
Authors: Bant Willem 
Published: October 2020

Abstract
In 1949, the Dutch publishing house A.J.G. Strengholt’s Uitgeversmaatschappij N.V. published the novel Dorstig paradijs. Through the eyes of Evelien van Eerdhuysen, the young, Dutch, female protagonist, author Adriaan Hulshoff presented an image of postwar Curaçao. In general, Dutch reviews of Hulshoff’s novel were quite positive and mentioned, for instance, the realistic representation of the island. Reviews published on Curaçao were very negative. At the moment the novel was published, Curaçao was fully in the news, because of the deliberations about the political status of the Dutch islands in the Caribbean. The question can be raised whether the image of Curaçao presented by Hulshoff was widespread in the Netherlands and representative of the way the Dutch looked at their Caribbean colonial possessions. One of the reasons why the book got much attention had to do with the name of the author who was hiding behind the pseudonym Adriaan Hulshoff. Most probably it was the well-known female writer Jo van Ammers-Küller, who after the Second World War, was banned from publishing because of collaborating with the Germans.
Os Canastreiros: uma minoria esquecida
Authors: Adão Clara de Oliveira , Oliveira Weder Antônio de 
Published: October 2020

O presente artigo visa abordar os pontos controvertidos sobre o Parque Nacional da Serra da Canastra e sua história, apresentando a dificuldade em conciliar o ideal de preservação ambiental implantado, com o respeito ao contexto cultural e social dos moradores da região. Estes moradores locais são os chamados “Canastreiros”, uma população tradicional que está alocada secularmente na região da Canastra. O intuito é demonstrar que é possível harmonizar os conflitos jurídicos oriundos deste embate entre a cultura dos tradicionais residentes na área, e a conservação do meio ambiente, respeitando o objetivo de proteção das Unidades de Conservação. Não é necessário retirar os particulares da área de preservação, tal como a permissividade de permanência não implica obrigatoriamente numa negligência ao meio ambiente. Objetiva-se a cooperação entre as partes, a fim de garantir que não haja grandes impactos ambientais, sem causar insegurança jurídica aos habitantes da área. Para tanto, a metodologia utilizada foi a pesquisa bibliográfica, com a realização de estudo de caso, pautada na análise de documentos, jurisprudências, doutrinas e estudos concernentes aos conflitos da Canastra.
Electron Scattering from Some Fp- Shell Nuclei with Inclusion the Effect of Short-Range Correlation
Authors: Hamoudi Adel K. , Abbas Mahmoud A. 
Published: October 2020

The effects of short-range correlation on elastic Coulomb (charge) form factors, charge density distributions as well as root mean square charge radii of various nuclei (for instance, 46, 48, 50Ti, 52, 54Cr, 56, 58Fe, and 72, 74, 76Ge nuclei) are examined. The one- and two body terms of the cluster expansion together with the single-particle harmonic oscillator wave functions are utilized. For the purpose of embedding these effects into the formulae of charge density and form factor we employ the correlation function of Jastrow-type. These formulae depend upon the short-range correlation parameter (which instigates from the Jastrow function) and the oscillator size parameter Both and are found by the fitting to the measured elastic form factors. It is noticed that the embedding of short-range correlation effects into the calculations of and is a requisite for the achievement of a vital change in the computed results and remarkably vital for the characterization of the measured data.
Synthesis and Characterization of New Polymers Bearing Tetrazole and Triazole Moieties with Studying their Corrosion Protection of Stainless Steel Surface in Hydrochloric Acid
Authors: Sadiq Amaal S. , Al-Tamimi Entesar O. 
Published: October 2020

A series of polymers containing1,2,4-triazole and tetrazole groups in their main chains were synthesized through several steps. Poly(acryloyl hydrazide) was first prepared and then subjected to a hydrazide reaction with phenyl isothiocyanate to give a 1,2,4-triazole ring (2). This polymer was introduced into a reaction with chloro acetylchloride to yield polymer (3), which was refluxed with sodium azide to give polymer (4). Polymer (5) was synthesized by the reaction of polymer (4) with acrylonitrile in the presence of NH4Cl as a catalyst. Finally, polymer (6) was synthesized by the electrochemical polymerization of polymer (5) using 316L stainless steel as an anti-corrosion coating. Polymer-coated and uncoated stainless steel was tested for corrosion safety in a solution of 0.1 M HCl, followed by Tafel and Potentiostatic procedures at a temperature of 293 K. Nano materials such as ZnO were applied to the monomer solution at different concentrations to enhance the corrosion resistance of the 316L stainless steel surface. The results showed that the performance values of corrosion protection for the polymer coating were increased with the introduction of the nano materials. Furthermore, 13C-NMR, 1H-NMR, and FTIR were recorded to confirm the structures of the poylmers, while their physical properties were tested using atomic force microscope (AFM) and scanning electron microscope (SEM).
Detection of Epstein Barr Virus Infection in Reactive Arthritis Patients
Authors: Al-Bayati Ola Hafedh Nsaif , Abood Walaa Najm , Salloom Dunya Fareed 
Published: October 2020

Reactive arthritis (ReA) is an incendiary joint inflammation that occurs few days to weeks after a gastrointestinal or genitourinary infection. The etiology of the disease is not well-known. Therefore, the present study included 80 females and 25 males, divided into 51 patients with reactive arthritis and 54 healthy individuals as control group. The study involved the detection of serum levels of anti-rheumatoid factor and anti-cyclic citrullinated peptide antibodies (anti-CCP) as well as those of CRP and C3 in all subjects. In addition, EBV levels were detected by Real Time-PCR technique. The results showed significantly increased levels (P < 0.05) of CRP, C3 and anti-CCP Ab in ReA patientsâ€™ group compared to the healthy control group (505.42 Â± 402.94 versus 255.62 Â± 135.5 U/ml, 61.20 Â± 100.64 versus 20.43 Â± 47.63 ng/ml and 35.11 Â± 30.0 versus 6.82 Â± 14.01 pg/ml, respectively), Also, the RF results demonstrated a significantly increased percentage in ReA patientsâ€™ group compared to a healthy control group (61.11 versus 37.25 %). While, the molecular study showed a non-significant increase in the percentage of EBV in ReA patientsâ€™ group compared to a healthy control group (17.65 versus 12.69 %). The results of this study lead to suggest that the immunological markers used may play a role in the development of ReA disease, while there was a non-significant association between EBV infection and ReA disease development.
Konsep Pengelolaan Air Limbah Kawasan Industri Makassar (KIMA)
Authors: Dewi Yashinta Kumala , Pratiwi Nurul , Jinca Muhammad Yamin 
Published: October 2020

Waste problems are one of the trigger factors that can hinder the growth and development of the city of Makassar, which should be able to balance growth and development. The selection of the waste disposal location into the Tallo River due to its location adjacent to the Makassar Industrial area, the waste construction pipeline that has been treated from the installation from the industrial waste treatment is channeled to the Tallo River. The Tallo River pollution condition with an indicator of IP value is equal to 1.38 including under mild pollution status. The purpose of this study is to find out how the ideal management of industrial wastewater is currently in KIMA and to plan the concept of industrial waste management which includes 3 components, namely the distribution, processing and disposal of wastewater networks so as not to have a negative impact on the environment. The analytical method used is analysis of quantity and quality with descriptive methods, comparative analysis and spatial analysis to analyze the location and land needed for KIMA industrial wastewater management. The results of the analysis show that the performance of existing comparative assessments and ideal KIMA limbah water management is at a value of 49.36% C, where the distribution network does not cover all zones, processing only 3 stages and the absence of utilization of treated water. So that the direction of the planning concept needed by KIMA at the initial stage is to complete the distribution network to all service zones by increasing the pipe size to 300 mm and adding 3 stages, procuring the utilization of processed water and the last capacity to 5,000 m3/day with a total area of ​​10,500 m2.

Keywords: Zone, Industry, Infrastructure, Sewerage, Makassar
Elastisitas dan Rasio Poisson Campuran Tanah Laterit dan Kapur Padam (Ca(OH)2)
Authors: Tribowo Haris , Tjaronge Muhammad Wihardi , Harianto Tri 
Published: October 2020

Kondisi infrastruktur jalan darat yang tidak memadai menjadikan jalur udara sebagai andalan untuk pengangkutan orang dan barang, termasuk berbagai kebutuhan pokok di Papua. Penelitian ini bertujuan untuk mengetahui nilai modulus elastisitas dan poisson rasio yang telah distabilisasi dengan kapur menggunakan curing air dan udara selama 7 hari. Metode yang digunakan dalam penelitian ini adalah metode eksperimental di laboratorium. Dimensi benda uji yang digunakan adalah silinder ukuran 53 x 106 mm. Sampel tanah yang digunakan dalam penelitian stabilisasi tanah ini diambil dari Tanah Merah Kabupaten Bovendigul. Campuran tanah lempung dan kapur dibuat dengan menggunakan kadar air sebesar 35%. Hasil pengujian kuat tekan menunjukkan bahwa rata-rata nilai modulus elastisitas (vertikal dan horizontal) pada curing air dan udara adalah masing-masing sebesar 122,82 MPa; 92,23 MPa dan 51,11 MPa; 424,43 MPa. Sedangkan rata-rata nilai poisson rasio adalah masing-masing sebesar 0,66 μ dan 0,06 μ.