bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demographic, spatial, and temporal dietary intake patterns among 526,774 23andMe research participants
Authors: Shelton Janie F. , Cameron Briana , Aslibekyan Stella ,   23andMe Research Team, Gentleman Robert 
Published: April 2020

AbstractObjectiveTo characterize dietary habits, their temporal and spatial patterns, and associations with body mass index (BMI) in the 23andMe study population.DesignWe present a large-scale cross-sectional analysis of self-reported dietary intake data derived from the web-based NHANES 2009-2010 dietary screener. Survey-weighted estimates for each food item were characterized by age, sex, race/ethnicity, education, and BMI. Temporal patterns were plotted over a 2-year time period, and average consumption for select food items was mapped by state. Finally, dietary intake variables were tested for association with BMI.SettingU.S. based adults 20-85 years of age participating in the 23andMe research program.ParticipantsParticipants were 23andMe customers who consented to participate in research (n=526,774) and completed web-based surveys on demographic and dietary habits.ResultsSurvey-weighted estimates show very few participants met federal recommendations for fruit: 2.6%, vegetables: 5.9%, and dairy intake: 2.8%. Between 2017-2019, fruit, vegetables, and milk intake frequency declined, while total dairy remained stable and added sugars increased. Seasonal patterns in reporting were most pronounced for ice cream, chocolate, fruits, and vegetables. Dietary habits varied across the U.S., with higher intake of sugar and calorie dense foods characterizing areas with higher average BMI. In multivariate-adjusted models, BMI was directly associated with intake of processed meat, red meat, dairy, and inversely associated with consumption of fruit, vegetables, and whole grains.Conclusions23andMe research participants have created an opportunity for rapid, large scale, real time nutritional data collection, informing demographic, seasonal and spatial patterns with broad geographical coverage across the U.S.
Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer’s disease
Authors: Pagoni Panagiota , Dardani Christina , Leppert Beate , Korologou-Linden Roxanna , Smith George Davey , Howe Laura D , Anderson Emma L , Stergiakouli Evie 
Published: April 2020

ABSTRACTBackgroundThere are very few studies investigating possible links between Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD) and Alzheimer’s disease and these have been limited by small sample sizes, diagnostic and recall bias. However, neurocognitive deficits affecting educational attainment in individuals with ADHD could be risk factors for Alzheimer’s later in life while hyper plasticity of the brain in ASD and strong positive genetic correlations of ASD with IQ and educational attainment could be protective against Alzheimer’s.MethodsWe estimated the bidirectional total causal effects of genetic liability to ADHD and ASD on Alzheimer’s disease through two-sample Mendelian randomization. We investigated their direct effects, independent of educational attainment and IQ, through Multivariable Mendelian randomization.ResultsThere was limited evidence to suggest that genetic liability to ADHD (OR=1.00, 95% CI: 0.98 to 1.02, p=0.39) or ASD (OR=0.99, 95% CI: 0.97 to 1.01, p=0.70) was associated with risk of Alzheimer’s disease. Similar causal effect estimates were identified when the direct effects, independent of educational attainment (ADHD: OR=1.00, 95% CI: 0.99 to 1.01, p=0.07; ASD: OR=0.99, 95% CI: 0.98 to 1.00, p=0.28) and IQ (ADHD: OR=1.00, 95% CI: 0.99 to 1.02. p=0.29; ASD: OR=0.99, 95% CI: 0.98 to 1.01, p=0.99), were assessed. Finally, genetic liability to Alzheimer’s disease was not found to have a causal effect on risk of ADHD or ASD (ADHD: OR=1.12, 95% CI: 0.86 to 1.44, p=0.37; ASD: OR=1.19, 95% CI: 0.94 to 1.51, p=0.14).ConclusionsIn the first study to date investigating the causal associations between genetic liability to ADHD, ASD and Alzheimer’s, within an MR framework, we found limited evidence to suggest a causal effect. It is important to encourage future research using ADHD and ASD specific subtype data, as well as longitudinal data in order to further elucidate any associations between these conditions.
BRAIN RE-IRRADIATION IN LUNG CANCER – NOT AN EXERCISE IN FUTILITY
Authors: Agarwal Jai Prakash , Karmakar Shreyasee , Tibdewal Anil , Mummudi Naveen 
Published: April 2020

ABSTRACTBACKGROUNDWhole brain radiation therapy (WBRT) is an effective palliative measure and provides durable symptom relief in lung cancer patients with multiple brain metastases (BM). Clinico-radiological progression of BM after WBRT is a common and challenging scenario; treatment is tailored, with various factors like driver mutation status, age, performance status, progression free interval and time since last irradiation influencing the treatment decision. Surgery or focal RT with stereotactic techniques may be an option for patients with oligo-metastases. However, they might not be a feasible option for patients with multiple BM. We aim to study the impact and outcome of patients with BM from lung cancer receiving re-WBRT for clinico-radiological progression.MATERIALS AND METHODSWe retrospectively analyzed patients with BM from lung cancer who were registered at Tata Memorial Hospital, Mumbai, India between January 2016 to January 2019 and had undergone two courses of WBRT. Data of patients were retrieved from electronic medical records. Patients were treated using conventional or conformal technique with either tele-cobalt or Linear accelerator.RESULTSOut of 446 patients with lung cancer, diagnosed and treated with WBRT for BM, 6% patients (n=28) received re-WBRT. There were 16 men and 12 women with a median age of 53 years (range 30 to 70 years). Primary histology was adenocarcinoma in all except two patients who had small cell histology. Eighteen patients had driver mutation positive disease (11 with EGFR and 7 with ALK mutation) and a majority of patients (54%) had BM at presentation. Clinico-radiological progression was the commonest indication of re-WBRT. A majority of these patients had developed new symptoms while about 25% had recurrence of previous symptoms. Mean Karnofsky performance score (KPS) prior to re-WBRT was more than 70 in 13 patients (57%). Mean time interval between the two courses of WBRT were 16 months (range 5-37 months). Most patients received WBRT using a conventional technique (91%) and were treated in a tele-cobalt unit (83%). Re-WBRT fractionation schedule was 25 Gy/10 fractions (n=17, 61%) or 20 Gy/5 fractions (n=10, 36%). Mean biological effective dose (BED2Gy) for the first and second courses of WBRT were 63Gy and 56Gy respectively. The average cumulative BED2Gy was 118.91Gy (range 116.25 – 120Gy). Almost all patients received short acting steroids during the course of re-WBRT. All patients except for one completed the course of treatment. At a median follow up of 2.5 years, median survival of patients after re-WBRT was 5 months. Median survival since re-WBRT was 8 months if pre first course of WBRT ds-GPA was 3.5-4 vs 1 month if it was 0-1 (p= 0.025).CONCLUSIONIn lung cancer patients with symptomatic progression of multiple BM and good prognostic features (driver mutation positive, good performance status and long time interval since last WBRT), re-WBRT is safe and associated with better outcomes.
Effect of hydrogen on semiconductor properties and pitting initiation of 2205 duplex stainless steel passivation film
Authors: Zheng Chuanbo , Huang Jiayan , Yi Gua 
Published: April 2020

Purpose
This paper aims to study the effect of current density of hydrogen charging on the semiconductor properties and pitting initiation of 2205 duplex stainless steel (DSS) passivation film.

Design/methodology/approach
In this work, the 2205 DSS is pre-hydrogenated and passivated. Then, the passivation film is tested by electrochemical impedance method, Mott–Schottky curve method and dynamic potential scanning method. The influences of hydrogen on the properties of the passivation film and the corrosion behavior of the matrix were studied by analyzing the curves obtained in the electrochemical test. The surface of the passivation film after pre-hydrogenation and anodic polarization was observed by using the ultra-depth three-dimensional microscopy and the scanning electron microscope. The integrity, density and corrosion morphology of the passivation film were studied and discussed.

Findings
With the increase of the hydrogen current density, the growth of the passivation film is hindered, the concentrations of donor and acceptor in the film are increased, the conductivity of the passivation film increases. In the anodic polarization, the dimensional passive current density increases with the increase of the hydrogen current density, and the pitting potential is reversed, the more likely the sample is pitting. In general, hydrogen hinders the formation of the passive film on duplex stainless steel, which increases the concentration of point defects in the passive film. Finally, the passive film is easy to crack and pitting.

Originality/value
The performance of passive film is an important condition to influence the corrosion behavior of stainless steel. However, little research has been done on the effects of hydrogen on the electrochemistry and pitting sensitivity of 2205 DSS passivation films. The effect of hydrogen on semiconductor properties and pitting initiation of 2205 DSS passivation film is needed to be investigated.
Income diversification and cost-efficiency of Vietnamese banks
Authors: Nguyen Phong Hoang , Pham Duyen Thi Bich 
Published: April 2020

PurposeThe study examines the impact of income diversification on cost efficiency of Vietnamese commercial banks over the period 2005–2017.Design/methodology/approachIncome diversification indicators are designed based on measures of diversifying loan portfolio. Besides the traditional model, we use the Fractional Regression to estimate the model with dependent variables defined on the unit interval.FindingsThrough the two-stage DEA analysis, we find that the income diversification has a positive impact on the cost efficiency of banks. In addition, this impact is stronger for unlisted banks and in the phase of banking system ongoing restructuring.Originality/valueThe use of a variety of income diversification measures and estimation methods for models with bounded dependent variable has provided a reliable empirical evidence of the advantages of implementing a strategy on structural diversity of both interest and non-interest income in the emerging banking markets such as Vietnam.
The nexus between corporate governance and intellectual capital in Vietnam
Authors: Tran Ngoc Phu , Van Loan Thi-Hong , Vo Duc Hong 
Published: April 2020

Purpose
This paper aims to examine the relationship between corporate governance and intellectual capital in the context of Vietnam. In this paper, corporate governance is proxied by various characteristics, including board size, a number of independent members in the board, board remuneration, major shareholder holding more than 20 per cent of the outstanding shares and duality of the CEO. In addition, intellectual capital is measured using the modified value-added intellectual coefficient model (MVAIC).

Design/methodology/approach
The study uses data of 45 Vietnamese listed firms during 2011-2018. The MVAIC model is used incorporating four components, namely, human capital, structural capital, capital used and relational capital. In addition, GMM regression technique is used in this paper.

Findings
Empirical findings from this paper indicate that key characteristics of corporate governance, except for board remuneration, may provide a negative effect on the efficient use of intellectual capital.

Research limitations/implications
Intellectual capital emerges as a new field of research that has not been widely examined in emerging countries such as Vietnam. As such, there have not been many studies focusing on understanding intellectual capital and its role in the performance of enterprises. Further studies can evaluate the relationship between intellectual capital and corporate performance, capital structure, corporate value and social responsibility. This study is limited to listed companies in Vietnam because of data limitations in an emerging market. Studies in the future should extend the sample and/or compare differences between manufacturing enterprises and financial institutions, or between countries.

Practical implications
Findings from this paper provide a valuable framework for executives, managers and policymakers in managing corporate governance and intellectual capital within the Vietnamese context.

Originality/value
To the best of the authors’ knowledge, this is the first empirical study that has been conducted to examine the relationship between corporate governance and intellectual capital in the context of Vietnam.
Influences on purchase intentions of organic food consumers in an emerging economy
Authors: Dangi Neeraj , Narula Sapna A. , Gupta Sandeep Kumar 
Published: April 2020

Purpose
This paper aims to investigate the determinants of organic food buying behaviour in an emerging economy like India, where organic food yet has low market share in spite of its potential. Using the theory of planned behaviour (TPB) as the underlying basis, it attempts to explain the effect of attitude, subjective norms and the perceived behaviour control (PBC) on buying intention towards organic food among respondents in Delhi-National capital region, India. Additionally, it attempts to discriminate functional and constructive attitudes.

Design/methodology/approach
A quantitative questionnaire survey approach was used on 306 respondents and multiple linear regression was used to validate the research model.

Findings
Attitudes and PBC have a significant positive impact on the intention to purchase organic food. This paper found subjective norms to be weak and barely significant to intention. The results conclude that health motives, past purchase behaviour, knowledge, affordability and trust in organic certification label are the main facilitators in organic food purchase. Primarily, the respondents see buying organic food regularly as being of value and enjoyable to them. A more favourable appearance vs conventional food was negatively related to behavioural intention.

Originality/value
This research could aid all stakeholders in the organic food sector, particularly emerging economies like India where the organic market is still nascent. It could be an essential driver to improve customer involvement and thus aid them in the decision-making process to choose organic food over conventional food. It also attempts to establish the usability of TPB in assessing functional attitudes based on constructive attitudes for organic food purchase.
Factors influencing liquidity position of Indian manufacturing companies
Authors: Tripathy Amit , Uzma Shigufta Hena 
Published: April 2020

PurposeThe purpose of this paper is to investigate the increasing demand for corporate liquidity and examines the various factors influencing the cash position of firms in India. The financial policy to hold cash gained impetus after the financial crisis when the companies faced a severe cash crunch. However, the firms operating in emerging nations have an imperfect market mechanism with stringent regulatory norms. Thus, this paper attempts to examine the determinants of corporate cash holdings in an emerging country like India.Design/methodology/approachThe paper focuses on the impact of various factors (leverage, firm size, profitability, growth along with other variables), on the cash structure of all the manufacturing companies listed on the Bombay stock exchange. The study employs panel data methodologies over a sample of 323 firms over a period of eight years from 2010 to 2017.FindingsSignificant estimators affecting cash holdings of a firm are the size of a firm, debt levels, tangibility, sales growth and research and development expense. Overall, the study finds evidence on the existence of Pecking Order theory in explaining the determinants of cash holdings in the Indian market.Research limitations/implicationsThe study attempts to explore the critical determinants of cash in the Indian context which can be useful for managers and academicians to understand how the key theories of cash holdings operate in an emerging economy like India.Originality/valueIndia is an emerging economy and has recently gained global attention and has become a hotspot for foreign investments. Thus, this paper explores pieces of evidence on the critical factors affecting cash holdings in India. The study would provide an understanding of the existing cash policy in the Indian context and attempts to find the changes in the financing structure adopted by the manufacturing industry in the given period.
The establishment of the OECD Asia-Pacific academy for tax and financial crime investigation
Authors: Matsuoka Akira 
Published: April 2020

Purpose
This viewpoint paper has two purposes: One is to argue that the Academy activities should increasingly be promoted and used for disseminating the practical and useful skills for the related law enforcement people who fight against financial crime, while the other is to contribute to the basis of discussions and further academy research.

Design/methodology/approach
This study summarizes and indicates potential usefulness of the new academy, specializing in the related social and political contexts in qualitative and descriptive ways.

Findings
This study indicates that the new academy activities in Japan would continue for a long time, thus providing immediately useful skillsets for the investigators and officers at the very frontline who face against various financial crimes.

Originality/value
While little research has been done about the series of related academy activities by OECD, this study describes the historical background and usefulness of the academy of the OECD in a specialized manner, thus showing its linkage with FATF.
A strategic decision making tool for new product and service design
Authors: Pugna Adrian Pavel , Potra Sabina Alina , Negrea Romeo 
Published: April 2020

PurposeThe present study aims to further research the theory of attractive quality for new offers by analyzing the HWWP (Health, Weapon, Wealth, Prospect) model and testing its uniformity. The purpose is to extend and refine the HWWP model based on meridian elasticity curves with the final scope of building a map for better understanding the potential value of the quality attributes in new product or strategic service design.Design/methodology/approachAfter a thorough analysis of the HWWP model for prepurchase value judgment, it has been observed that the classical form often presents a concentration of the quality attributes in its graphic representation, which limits managerial decision making. This paper presents a new methodology for testing the uniformity of the current HWWP model and a generalized approach for understanding the potential lifecycle of the new offer's features.FindingsThe results of the presented case study validate the novel tool’s applicability and can serve as a reference for managers to adequately classify customer requirements as the first step toward strategic design.Originality/valueThe author’s main contributions are: to have analyzed the current HWWP model and observed the limitations of this approach; to have proposed a statistical simple method used to test the uniformity of the HWWP model; to have developed a generalized new HWWP model that adequately explores each feature value and potential lifecycle base on meridian slices and elasticity orbits.
Do narcissistic CEOs rock the boat?
Authors: Aabo Tom , Hoejland Frederik , Pedersen Jesper 
Published: April 2020

PurposeThe purpose of this paper is to investigate the role of narcissistic supply for the association between CEO narcissism and corporate risk taking.Design/methodology/approachThe authors investigate a sample of 281 non-financial S&P 1500 firms and a corresponding 457 CEOs in the 10-yr period 2006–2015.FindingsThe association between CEO narcissism and corporate risk taking depends on the admiration, attention, and affirmation of own superiority (“narcissistic supply”) that the CEO receives given her/his current position. Thus, a narcissistic CEO with an insufficient narcissistic supply (small firm/small compensation) will crave for more and take more risks (“rock the boat”) while a narcissistic CEO with a sufficient narcissistic supply (large firm/large compensation) will protect the status quo and be reluctant to take new risks. Specifically, the authors find that a change from a slightly narcissistic CEO to a strongly narcissistic CEO, for positions entailing limited (abundant) narcissistic supply, is associated with an increase (a decrease) in corporate risk of 6%–8% (11%–27%).Originality/valuePrevious research indicates a positive association between CEO narcissism and corporate risk taking in specific domains such as M&A and R&D activities. This paper provides a novel contribution to the existing literature by identifying and assessing the important role of narcissistic supply for the association between CEO narcissism and corporate risk taking in general.
Corporate social responsibility practices as the apex of giving?
Authors: Etogo Gabriel 
Published: April 2020

Purpose
This paper aims to analyze corporate social responsibility (CSR) practices from the epistemological position advocated by the MAUSS. The latter, beyond paying tribute to Marcel Mauss, refers to the project of combating all utilitarian and economistic reductionism.

Design/methodology/approach
This paper discusses the question of the definition of CSR practices by basing the analysis on the definition proposed by Etogo, which considers CSR practices as all forms of key-giving transactions, material or immaterial, which update the primary and secondary links between the company and its human and non-human environment.

Findings
The sociology of CSR practices is seeking the notion of gift in companies which are places of profit and utilitarian calculus. This research emphasizes that the triple duty of giving-receiving-returning structures CSR practices. The approach extends the perspective of Godbout’s gift, which recalls how Homo donator, along with Crozier and Friedberg’s Homo strategus, is at the center of CSR practices.

Research limitations/implications
The proposed approach comes up against a particular limit. Despite its sociological fruitfulness, the gift paradigm is not immediately operational from a managerial point of view.

Practical implications
This reflection suggests to consider that CSR practices participate in a form of reconfiguration of the efficiency of the company insofar as they call into question the partial analysis of the efficiency of the company for the benefit of the shareholders. For CSR practices to be effective, managers must understand the interdependence between society and business: the well-being of society and business development cannot be opposed. Managers therefore need to integrate CSR practices into the company's strategy.

Social implications
This reflection can have interesting implications in terms of building citizen identity. Specifically, it is a question of rebalancing the link between social and economic logics, by legitimizing the social utility of companies as well as their involvement in the organization and functioning of the city.

Originality/value
This note seeks to emphasize the fecundity of the epistemological position advocated by the MAUSS to reconstruct the role of CSR practices by adopting a balanced approach.