bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrated analysis of transcriptome, methylome and copy number aberrations data of marginal zone lymphoma and follicular lymphoma in dog
Authors: Giannuzzi Diana , Giudice Luca , Marconato Laura , Ferraresso Serena , Giugno Rosalba , Bertoni Francesco , Aresu Luca 
Published: March 2020

AbstractMarginal zone lymphoma (MZL) and follicular lymphoma (FL) are classified as indolent B‐cell lymphomas in dogs. Aside from the clinical and histopathological similarities with the human counterpart, the molecular pathogenesis remains unclear. We integrated transcriptome, genome‐wide DNA methylation and copy number aberration analysis to provide insights on the pathogenesis of canine MZL (n = 5) and FL (n = 7), also comparing them with diffuse large B‐cell lymphoma (DLBCL). Transcriptome profiling highlighted the presence of similar biological processes affecting both histotypes, including BCR and TLR signalling pathways. However, FLs showed an enrichment of E2F targets, whereas MZLs were characterized by MYC‐driven transcriptional activation signatures. FLs showed a distinctive loss on chr1 containing CEACAM23 and 24, conversely MZLs presented multiple recurrent gains on chr13, where MYC is located. The distribution of methylation peaks was similar between the two histotypes. Integrating data from the three omics, FLs resulted clearly separated from MZLs and DLBCL dataset. MZLs showed the enrichment of FoxM1 network and TLR associated TICAM1‐dependent IRFs activation pathway. However, no specific signatures differentiated MZLs from DLBCLs. In conclusion, our study presents the first comprehensive analysis of molecular and epigenetic pathogenesis of canine FL and MZL.
Weed seedling emergence in contrasting fodder crop systems following 30 years of cultivation in the lowlands of Northern Italy
Authors: Borrelli Lamberto , Pecetti Luciano 
Published: March 2020

AbstractFive fodder crop systems of different intensity (ranging from a double annual crop of Italian ryegrass + silage maize to a permanent meadow) were adopted for 30 years in the lowlands of Northern Italy under two input levels, differing mainly in their provision of organic fertiliser (manure). Herbicides were used in the maize crops included in all systems, except the meadow. After 30 years, the weed seedbank of all systems and input levels were assessed by the seedling emergence technique on soil samples from each plot. The cropping systems determined the abundance and composition of the weed assembly. Relatively few, frequent species made up the majority of the emerged seedlings in all systems, and there was no relationship between the total number of emerged seedlings and the mean number of species recorded in the different systems. Arabidopsis thaliana and Oxalis corniculata were abundant in the annual double crop and in the 3‐ and 6‐year rotations that also comprised the annual double crop. These weeds, however, were unlikely to represent a major threat to the crops, due to their vigour and growth period. The permanent meadow tended to greater weed biodiversity than the other systems. The application of manure favoured the seedbank of species such as Lolium multiflorum, Digitaria sanguinalis and A. thaliana. Weed communities in the different systems were mainly determined by herbicide application, (through the ability of weeds to avoid its effects, determined by the weed life history and emergence period) and manure application (with its possible dual effect of spreading weed seeds and favouring nitrogen‐responsive weeds).
Sequential Time-Optimal Algorithm for Extended Path Tracking Problem
Authors: Csorvási Gábor , Vajk István 
Published: March 2020

Abstract
This paper presents a fast and easily implementable path tracking algorithm for robots. Usually, for a path tracking problem, the goal is to move the robot on a predefined path, while the joint velocities and accelerations are kept within their limits. This paper deals with the extended case, constraining the forces applied to the objects at the manipulator. First, a problem with a special set of constraints is presented, and a sequential solver method is formulated. The presented sequential solver algorithm has significant computational benefits compared to the direct transcription approach. Then, a practical example is introduced where the proposed algorithm can be applied. At last, the algorithm is validated by real-life experimental results with a six degrees-of-freedom robotic arm.
Coupled Dynamics for Noncontact Piezoelectric Motor Modulated by Electromagnetic Force
Authors: Wang Tingting , Xing Jichun , Xu Lizhong 
Published: March 2020

Abstract
A coupled dynamics model for a noncontact piezo-electric motor modulated by electromagnetic force is presented in this paper. Coupled dynamic equations of the motor system are derived. From the equations, the natural frequency, and modal function equations of the motor system are provided. Considering the nonlinear constitutive relation of a piezo-electric stack, nonlinear coupled dynamic equations of the motor system are established, and the nonlinear vibration frequency equation of the motor system is obtained. The linear and nonlinear coupled natural frequencies, modal shapes, and forced responses of the motor system are studied using the obtained equations. Modal shapes of the motor system are then classified, and the deviation between the nonlinear vibration frequency and linear natural frequency of the motor system and its variation with system parameters are analyzed. The research provides a useful reference for design and analysis of the dynamic behavior of the motor system.
Dynamic Impedance Monitoring for Large Diameter Vessel Sealing Using Bipolar Electrosurgery
Authors: Li Xiaoran , Li Wei , Yang Che-Hao , Chen Roland K. 
Published: March 2020

Abstract
Vessel sealing using bipolar electrosurgery is becoming a common practice in modern operating rooms. Despite all the advantages such as faster operation, less bleeding, and shorter postsurgery recovery time, side effects including sticking, charring, and rebleeding still occur, leading to increased surgery time and sometimes fatal complications. Tissue impedance during the electrosurgical process has been used to determine the electrical power of the process. However, little has been done to understand the dynamic tissue impedance and its effectiveness in monitoring the vessel sealing process. Moreover, the samples used in previous studies all had small diameters of 2–5 mm. In this study, an experimental setup was developed to perform vessel sealing tests using large-diameter blood vessel samples with mimicking blood flow. The tissue impedance during the heating process was obtained. Burst pressures after sealing were measured. A finite element simulation model was developed to understand the dynamic impedance behavior. It is seen that the tissue impedance increases rapidly in the beginning of the heating process and remains at a level that is several orders of magnitude higher than the initial value. This rapid impedance increase indicates protein denaturing, thus can be used to monitor the electrosurgical vessel sealing process. An impedance-based monitoring algorithm was developed, with which a burst pressure at least twice the normal human systolic blood pressure was achieved.
System Performance Analysis of Overlap Coupled Control Units
Authors: Liu Mingsheng , Wang Jinrong 
Published: March 2020

Abstract
The overlap coupled control unit is widely used in hotels, dormitory buildings, hospitals, and office buildings. Energy simulation models are developed to assess changes in energy consumption and humidity levels due to changes in various system parameters. The simulation results show that the energy consumption of the overlap unit is 3 to 5 times higher than the optimal energy consumption. To improve the energy performance, the following measures are recommended: (1) use the variable air volume technique; (2) balance total airflow based on actual peak load; and (3) replace overlap with humidistat. Quick open valves are also found to improve relative humidity control.
Performance of the SES/Boeing Dish Stirling System
Authors: Stone Kenneth W. , Leingang Eric , Rodriguez Gerry , Paisley Jonathan , Nguyen Jean-Paul , Mancini Dr. Thomas , Nelving Hans 
Published: March 2020

Abstract
The operation of Stirling Energy Systems’ Stirling Dish system and components, originally built and tested during the mid 1980s by McDonnell Douglas [Lopez, 1993] and operated in the Department of Energy Dish Engine Critical Components (DECC) Program since 1998 is presented in this paper. The operating time, performance, and system availability are presented. The data show that the Kockums Stirling engine has accumulated over 8,200 hours of on-sun operating time, has generated over 115 MWh of electrical energy, and has accumulated more than 15,000 hours of test cell operating time since April of 1998 in the DECC Program. Power measurements indicate that the system performs the same as it did in the 1980s. The daily energy plots show net energy efficiency between 24% to 27% when the daily energy available exceeds 600 kWh. System availability data during the 1998/1999 testing period shows that the system was available over 94% of the time when the insolation exceeded 300 W/m2.
The data presented herein focuses on three power conversion units (PCUs) and two solar concentrators, which are tested in various combinations and as individual system components. During later parts of the testing cycle, one of the engines, PCU 209, included newly manufactured Stirling engine components (regenerators and coolers) as part of a manufacturing cost reduction program.
Hybrid PV/Fuel Cell System Design and Simulation
Authors: El-Shatter Thanaa F. , Eskandar Mona N. , El-Hagry Mohsen T. 
Published: March 2020

Abstract
In this paper, a hybrid Photovoltaic (PV)-fuel cell generation system employing an electrolyzer for hydrogen generation is designed and simulated. The system is applicable for remote areas or isolated loads. Fuzzy regression model (FRM) is applied for maximum power point tracking (MPPT) to extract maximum available solar power from PV arrays under variable insolation conditions. The system incorporates a controller designed to achieve continuous supply power to the load via the PV array or the fuel cell, or both according to the power available from the sun. The simulation results show that the system can run without power shortage for more than four days even in case of zero insolation.
Applicability of Stand-Alone Building-Integrated Photovoltaic Home Systems in Kenya
Authors: Ogoli David Mwale , Goswami D. Yogi 
Published: March 2020

Abstract
The Kenyan photovoltaic industry has been growing steadily in recent years. Since 1990 more than 2.5 megawatts of photovoltaic capacity have been sold in Kenya and 60% of these sales have gone into home systems as part of new energy supplies. The demand for energy in Kenya exceeds the supply and for this reason renewable energy is regarded a priority in the energy sector. A solution to this problem lies in four areas: technology development, environmental protection, energy economics and socio-cultural adjustments. This paper discusses the state of current research and applications of stand-alone building-integrated PV home systems by looking at the possibilities and limitations in this developing country. Houses need a PV panel-surface area of about 36m2 to meet basic energy needs.
Prediction of Building Integrated Photovoltaic Cell Temperatures
Authors: Davis Mark W. , Fanney A. Hunter , Dougherty Brian P. 
Published: March 2020

Abstract
A barrier to the widespread application of building integrated photovoltaics (BIPV) is the lack of validated predictive performance tools. Architects and building owners need these tools in order to determine if the potential energy savings realized from building integrated photovoltaics justifies the additional capital expenditure. The National Institute of Standards and Technology (NIST) seeks to provide high quality experimental data that can be used to develop and validate these predictive performance tools.
The temperature of a photovoltaic module affects its electrical output characteristics and efficiency. Traditionally, the temperature of solar cells has been characterized using the nominal operating cell temperature (NOCT), which can be used in conjunction with a calculation procedure to predict the module’s temperature for various environmental conditions. The NOCT procedure provides a representative prediction of the cell temperature, specifically for the ubiquitous rack-mounted installation. The procedure estimates the cell temperature based on the ambient temperature and the solar irradiance. It makes the approximation that the overall heat loss coefficient is constant. In other words, the temperature difference between the panel and the environment is linearly related to the heat flux on the panels (solar irradiance).
The heat transfer characteristics of a rack-mounted PV module and a BIPV module can be quite different. The manner in which the module is installed within the building envelope influences the cell’s operating temperature. Unlike rack-mounted modules, the two sides of the modules may be subjected to significantly different environmental conditions.
This paper presents a new technique to compute the operating temperature of cells within building integrated photovoltaic modules using a one-dimensional transient heat transfer model. The resulting predictions are compared to measured BIPV cell temperatures for two single crystalline BIPV panels (one insulated panel and one uninsulated panel). Finally, the results are compared to predictions using the NOCT technique.
Discussion of Strategies for Mounting Photovoltaic Arrays on Rooftops
Authors: Barkaszi Stephen F. , Dunlop James P. 
Published: March 2020

Abstract
The mechanical attachment of photovoltaic (PV) arrays to rooftops presents a number of unique and challenging issues for system designers and installers. With a resurgence of roof-mounted PV installations due to increasing duel costs and decreasing PV system prices, the Florida Solar Energy Center (FSEC) has accelerated its investigations of array mounting strategies, with the objectives of identifying key performance and cost parameters from a systems engineering perspective. Two principal classifications can be defined for rooftop PV array mounting systems: building-integrated (BIPV) and building-attached (BAPV) or standoff designs. The various attachment methods within these categories each have pros and cons that affect the labor and cost associated with the install and the system performance. An overview and assessment of some existing rooftop PV array attachment methods or mounting approaches, and their advantages and disadvantages with respect to key design criteria are presented to assist designers and installers in the selection of the appropriate method for a given project.
Pulsed Gas Feeding for Stoichiometric Operation of a Gas-Solid Vortex Flow Solar Chemical Reactor
Authors: Kräupl Stefan , Steinfeld Aldo 
Published: March 2020

Abstract
The thermodynamic implications of conducting the solar combined ZnO-reduction and CH4-reforming under stoichiometric and non-stoichiometric conditions are examined. For a solar flux concentration ratio of 5000 and for a solar cavity-receiver operating at 1300 K, the solar thermal conversion efficiency is 55% for a stoichiometric molar ratio of ZnO and CH4, and decreases by 50% when using excess methane by a factor 10 over the stoichiometric molar amount. A technical solution for operating a gas-solid vortex-flow solar reactor under stoichiometric conditions was established by using a pulsed-feed of methane to carry out the particles of ZnO. Using this technique, nearly stoichiometric operation was demonstrated with a prototype reactor in a high-flux solar furnace, thereby opening up a means for efficient conversion of sunlight into chemical fuels.
Sediment sources and transport by the Kahiltna Glacier and other catchments along the south side of the Alaska Range, Alaska
Authors: Matmon A. , Haeussler P.J. , Team ASTER 
Published: March 2020

AbstractErosion related to glacial activity produces enormous amounts of sediment. However, sediment mobilization in glacial systems is extremely complex. Sediment is derived from headwalls, slopes along the margins of glaciers, and basal erosion; however, the rates and relative contributions of each are unknown. To test and quantify conceptual models for sediment generation and transport in a simple valley glacier system, we collected samples for 10Be analysis from the Kahiltna Glacier, which flows off Denali, the tallest mountain in North America. We collected angular quartz clasts on bedrock ledges from a high mountainside above the equilibrium line altitude (ELA), amalgamated clast samples from medial moraines, and sand samples from the river below the glacier. We also collected sand from nine other rivers along the south flank of the Alaska Range. In the upper catchment of the Kahiltna drainage system, toppling, rockfall, and slab collapse are significant erosional processes. Erosion rates of hundreds of millimeters per thousand years were calculated from 10Be concentrations. The 10Be concentrations in amalgamated samples from medial moraines showed concentrations much lower than those measured from the high mountainside, a result of the incorporation of thick, and effectively unexposed, blocks into the moraine, as well as the incorporation of material from lower-elevation nearby slopes above the moraines. The 10Be sediment samples from downstream of the Kahiltna Glacier terminus showed decreasing concentrations with increasing distance from the moraine, indicating the incorporation of material that was less exposed to cosmic rays, most likely from the glacier base as well as from slopes downstream of the glacier. Taken together, 10Be concentrations in various samples from the Kahiltna drainage system indicated erosion rates of hundreds of millimeters per thousand years, which is typical of tectonically active terrains. We also measured 10Be concentrations from river sediment samples collected from across the south flank of the Alaska Range. Calculation of basinwide weighted erosion rates that incorporated hypsometric curves produced unrealistically high erosion rates, which indicates that the major source of sediment was not exposed to cosmic rays and was primarily derived from the base of glaciers. Moreover, the apparently high erosion rates suggest that parts of each drainage system are not in erosional steady state with respect to cosmogenic isotope accumulation.
Identifying the predictors of avoidable emergency department attendance after contact with the NHS 111 phone service: analysis of 16.6 million calls to 111 in England in 2015–2017
Authors: Egan Mark , Murar Filip , Lawrence James , Burd Hannah 
Published: March 2020

ObjectivesTo measure the frequency of patients making avoidable emergency department (ED) attendances after contact with NHS 111 and to examine whether these attendances can be predicted reliably.DesignAnalysis of 16 563 946 calls made to 111, where each call was linked with a record of whether the patient attended ED within 24 hours.SettingAll regions of England from March 2015 to October 2017.Participants and dataOur main regression model used a sample of 10 954 783 calls, each with detailed patient-level information.Main outcomeWhether patients made an unadvised, non-urgent type 1 ED (‘avoidable') attendance within 24 hours of calling 111.ResultsOf 16 563 946 calls to 111, 12 894 561 (77.8%) were not advised to go to ED (ie, they were advised to either attend primary care, attend another non-ED healthcare service or to self-care). Of the calls where the patient was not advised to go to the ED, 691 783 (5.4%) resulted in the patient making an avoidable ED attendance within 24 hours. Among other factors, calls were less likely to result in these attendances when they received clinical input (adjusted OR 0.52, 95% CI 0.51 to 0.53) but were more likely when the patient was female (OR 1.07, 95% CI 1.06 to 1.08) or aged 0–4 years (OR 1.34, 95% CI 1.33 to 1.35).ConclusionsFor every 20 calls where 111 did not advise people to attend the ED, 1 resulted in avoidable ED attendance within 24 hours. These avoidable attendances could be predicted, to a certain extent, based on call characteristics. It may be possible to use this information to help 111 call handlers identify which callers are at higher risk of these attendances.
Cohort profile: social well-being and determinants of health study (SWADES), Kerala, India
Authors: M D Saju , Nukala Lovakanth , Shekhar Rameela , Gomez Keith , Varghese Bindiya M , Benny Anuja Maria , Scaria Lorane , Prabhu Sphoorthi , Jotheeswaran Amuthavalli Thiyagarajan 
Published: March 2020

PurposeIn response to the need for more advanced and longitudinal data concerning chronic diseases, behavioural risk factors and social support systems in India, the SWADES (Social Well-being and Determinants of Health Study) was established.ParticipantsAt baseline, 997 adults aged 30 years and over, living in the semi-urban area were interviewed in their home.Findings to dateData collected included self-reports of demographic details, health, depression, morbid conditions and healthcare utilisation, risk factors (physical, behavioural and social) of chronic diseases, common mental disorders, out-of-pocket expenditure, social support network, social cohesion, disability, education and wealth. Objective data for hypertension, diabetes and cognitive function were also collected.Future plansThe first annual follow-up interviews were completed in 2019; the subsequent annual follow-up will be conducted until 2030. The SWADES data are held at the International Centre for Consortium Research in Social Care (ICRS), Rajagiri College of Social Science, Kerala, India. Procedures for data access, information on collaborations, publications and other details can be found at (http://icrs.in).