bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Multiferroic Filler on the AC Response of Bi1‐xBaxFeO3 doped PVA:NH4CH3COO Nanocomposite Gel Polymer Electrolytes
Authors: Singh C. P. , Shukla P. K. , Agrawal S. L. 
Published: December 2019

AbstractThe frequency dependent AC conductivity and dielectric studies of multiferroic filler (Bi1‐xBaxFeO3) doped nanocomposite gel polymer electrolyte (NCGPEs) based on PVA:(NH4CH3COO) are investigated in the present work. The nano composite gel polymer electrolyte systems are synthesized for various filler concentrations by solution cast method. The effect of filler concentration on ionic conductivity is studied using AC impedance technique in the frequency range 1–106 Hz. X‐ray diffraction studies reveal the formation of nanocomposite gel polymer electrolyte. The low frequency dispersion in the dielectric response of electrolytes shows the relaxation contribution is superimposed with electrode polarization effects. The relaxation peaks in the NCGPEs are found to shift toward higher frequency side with increasing filler concentration and are suitably correlated to change in morphology of the gel electrolyte system. The variation of AC conductivity with frequency is seen to obey Jonscher's universal power law with the exception of small deviation in the low frequency regime. Modulus formalism of dielectric response suggests that the ion transport is strongly coupled to the polymer segmental motion.
Polyvinylpyrrolidone (PVP) with Ammonium Iodide (NH4I) and 1‐Hexyl‐3‐Methylimidazolium Iodide Ionic Liquid Doped Solid Polymer Electrolyte for Efficient Supercapacitors
Authors: Singh Diksha , Gupta Meenal , Singh Ram Chandra , Pandey Shri Prakash , Karn Rakesh Kumar , Singh Pramod Kumar 
Published: December 2019

AbstractIonic liquid‐doped poly(vinylpyrrolidone), ammonium iodide (NH4I) ion conducting polymer electrolytes are prepared by solution cast technique. Ionic liquid (IL), 1‐hexyl‐3‐methylimidazolium (HMImI) is then added to increase the ionic conductivity of polymer electrolytes by reducing the crystallinity of polymer electrolyte. Fourier transform infrared spectroscopy confirms the complex formation as well as composite nature. Polarized optical microscopy affirms the reduction of crystallinity in polymer electrolyte by IL doping. Electrochemical double layer capacitors are then assembled using maximum conducting polymer electrolyte and porous carbon‐based electrodes which shows excellent specific capacitance.
Transcatheter intra‐arterial perfusion (TRIP)‐MRI biomarkers help detect immediate response to irreversible electroporation of rabbit VX2 liver tumor
Authors: Figini Matteo , Zhou Kang , Pan Liang , Sun Chong , Wang Bin , Hu Su , Yang Jia , Shangguan Junjie , Eresen Aydin , Velichko Yury , Yaghmai Vahid , Zhang Zhuoli 
Published: December 2019

PurposeIrreversible electroporation (IRE) is a nonthermal tissue ablation technique that represents a promising treatment option for unresectable liver tumors, but the effectively treated zone cannot be reliably predicted. We investigate the potential benefit of transcatheter intra‐arterial perfusion (TRIP) ‐MRI for the early noninvasive differentiation of IRE zone from surrounding reversibly electroporated (RE) zone.MethodsSeventeen rabbits with VX2 liver tumors were scanned with morphological and contrast‐enhanced MRI sequences approximately 30 min after IRE tumor ablation. Quantitative TRIP‐MRI perfusion parameters were evaluated in IRE zone and RE zone, defined according to histology. MRI and histology results were compared among zones using Wilcoxon rank‐sum tests and correlations were evaluated by Pearson’s correlation coefficient.ResultsThere were significant differences in area under the curve, time to peak, maximum and late enhancement, wash‐in and wash‐out rates in the tumor IRE zones compared with the boundary tumor RE zones and untreated tumors. Histology showed significantly fewer tumor cells, microvessels and significantly more apoptosis in tumor IRE zones compared with tumor RE zones (−51%, −66% and +185%, respectively) and untreated tumors (−60%, −67%, and +228%, respectively). A strong correlation was observed between MRI and histology measurements of IRE zones (r = 0.948) and RE zones (r = 0.951).ConclusionTRIP‐MRI demonstrated the potential to detect immediate perfusion changes following IRE liver tumor ablation and effectively differentiate the IRE zone from the surrounding tumor RE zone.
Donor selection in a pediatric stem cell transplantation cohort using PIRCHE and HLA‐DPB1 typing
Authors: Stenger Wiebke , Künkele Annette , Niemann Matthias , Todorova Kremena , Pruß Axel , Schulte Johannes H. , Eggert Angelika , Oevermann Lena 
Published: December 2019

AbstractBackgroundNew strategies to optimize donor selection for hematopoietic stem cell transplantation (HSCT) have mainly been evaluated in adults, but the disease spectrum requiring HSCT differs significantly in children and has consequences for the risk of complications, such as graft‐versus‐host disease (GvHD).ProceduresHere we evaluated whether HLA‐DPB1 and Predicted Indirectly ReCognizable HLA‐Epitope (PIRCHE) matching can improve donor selection and minimize risks specific for a pediatric cohort undergoing HSCT in Berlin between 2014 and 2016.ResultsThe percentage of HLA‐DPB1–mismatched HSCT in the pediatric cohort was in line with the general distribution among matched unrelated donor HSCT. Nonpermissive HLA‐DPB1 mismatches were not associated with a higher incidence of GvHD, but the incidence of relapse was higher in patients undergoing HSCT from HLA‐DPB1–matched transplantations. High PIRCHE‐I scores were associated with a significantly higher risk for developing GvHD in patients undergoing HSCT from nine of ten matched unrelated donors. This finding persisted after including HLA‐DPB1 into the PIRCHE analysis.ConclusionsImplementing PIRCHE typing in the donor selection process for HSCT in children could particularly benefit children with nonmalignant diseases and support further validation of PIRCHE‐based donor selection in a larger number of children treated at different sites.
Targeting pharmacophore with probe‐reactivity‐guided fractionation to precisely identify electrophilic sesquiterpenes and its activity of anti‐TNBC
Authors: Jiang QingLi , Zhu ZhiHui , Shou PanTing , Teng Fei , Zhu Ying , Zhao HuaJun , Yang Bo 
Published: December 2019

AbstractIntroductionInnovative strategy is urgently needed to precisely discover novel natural products as lead compounds for development of new drugs against orphan diseases such as triple‐negative breast cancer (TNBC). Herein, we describe a targeting pharmacophore with probe‐reactivity‐guided strategy for the discovery of electrophilic sesquiterpene (ES), a class of bioactive natural product.ObjectiveThis study aimed to identify pharmacophore, based on pharmacophore with probe‐reactivity‐guided strategy for precisely discovering ESs from ethyl acetate extract of Eupatorium chinense L. (EEEChL)MethodologyMTT assay combined with ultra‐performance liquid chromatography (UPLC) analysis was used to identify pharmacophore. UPLC‐mass spectrometry (MS) was applied to carefully compare the intrinsic reactivity characteristics of two chemoselective nucleophilic probes: glutathione (GSH) and 4‐bromothiophenol (BTP) reaction with ESs. ESs was isolated and identified from EEEChL by phytochemical methods. Furthermore, stoichiometric ratio and binding site of one typical ES 8β‐[4′‐hydroxytigloyloxy]‐5‐desoxy‐8‐desacyleuparotin (HDDE) reaction with BTP were studied by UPLC‐quadrupole time‐of‐flight (Q‐TOF)‐MS and two‐dimensional nuclear magnetic resonance (NMR).ResultsEleven ESs were identified from EEEChL, MTT assay illustrated that all of the 11 ESs possess fairly good anti‐TNBC activityConclusionsElectrophilic groups were confirmed as pharmacophore of bioactive compounds contained in EEEChL. An optimised halogenated aromatic probe BTP furnishes ES‐BTP conjugates that are highly conspicuous via MS by virtue of a unique isotopic bromine signature, conjugates also have a considerable separation on C18 column. The new probe‐reactivity‐guided strategy can effectively improve the traditional bioassay‐guided approaches, and significantly increase the probability of obtaining designated bioactive compounds.
Validation of claims‐based algorithms for psoriatic arthritis
Authors: Lee Hemin , Ford Julia A. , Jin Yinzhu , Cho Soo‐Kyung , Santiago Ortiz Adrian J. , Tong Angela Y. , Kim Seoyoung C. 
Published: December 2019

AbstractPurposeAn increasing number of new medications are being developed and approved for psoriatic arthritis (PsA). To generate real‐world evidence on comparative safety and effectiveness of these drugs, a claims‐based algorithm that can accurately identify PsA is greatly needed.MethodsTo identify patients with PsA, we developed seven claims‐based algorithms based on a combination of diagnosis codes and medication dispensing using the claims data from Medicare parts A/B/D linked to electronic medical records (2012‐2014). Two physicians independently conducted a chart review using the treating physician's diagnosis of PsA as the gold standard. We calculated the positive predictive value (PPV) and 95% confidence intervals of each algorithm.ResultsOf the total 2157 records identified by the seven algorithms, 45% of the records had relevant clinical data to determine the presence of PsA. The PPV of the algorithms ranged from 75.2% (algorithm 1: ≥2 diagnosis codes for PsA and ≥1 diagnosis code for psoriasis) to 88.6% (algorithm 7: ≥2 diagnosis codes for PsA with ≥1 code by rheumatologist and ≥1 dispensing for PsA medication). Having ≥2 diagnosis codes and ≥1 dispensing for PsA medications (algorithm 6) also had PPV of 82.4%.ConclusionsAll seven claims‐based algorithms demonstrated a moderately high PPV of 75% to 89% in identifying PsA. The use of ≥2 diagnosis codes plus ≥1 prescription claim for PsA appears to be a valid and efficient tool in identifying PsA patients in the claims data, while broader algorithms based on diagnoses without a prescription claim also have reasonably good PPVs.
Comparison between single‐site and multiport robot‐assisted hysterectomy in obese patients with endometrial cancer: An Italian multi‐institutional study
Authors: Corrado Giacomo , Mereu Liliana , Bogliolo Stefano , Cela Vito , Gardella Barbara , Sperduti Isabella , Certelli Camilla , Pellegrini Alice , Posar Giulia , Zampa Ashanti , Tateo Saverio , Gadducci Angiolo , Spinillo Arsenio , Vizza Enrico 
Published: December 2019

AbstractBackgroundThe aim of this study is to compare robotic single‐site hysterectomy (RSSH) and robotic multiport hysterectomy (RMPH) for endometrial cancer (EC) in obese patients in terms of surgical outcomes.MethodsThis retrospective study compares RSSH with RMPH in obese patients with EC and FIGO stages I to II divided in three classes according to their body mass index (BMI): class A (30‐34.9 kg/m2), class B (35‐39.9 kg/m2), and class C (>40 kg/m2).ResultsWe included 225 patients (RSSH: 76; RMPH: 149). The operative time and estimated blood loss (EBL) were lower in the A class of the RSSH group. The EBL and the conversion rate increased when the BMI increased in the RSSH group. The hospital stay was higher in the A class of the RMPH group.ConclusionsThe advantages of RSSH in terms of reduced invasiveness remain true only in the first BMI class, whereas they are lost when the BMI increased.
A Comprehensive Topological Analysis of a Novel Flavonoid Extracted from Brazilian Cerrado Plants
Authors: Silva Marianna C. , Sallum Lóide O. , Menezes Antônio C. S. , Camargo Ademir J. , Napolitano Hamilton B. 
Published: December 2019

AbstractEpicatechin is a bioactive compound that has several biological functions, and can be found in a number of Brazilian Cerrado plants. The compound (2R,3R)‐2‐(3,4‐dihydroxyphenyl)‐3,4‐dihydro‐2H‐1‐benzopyran‐3,5,7‐triol (EPC) was extracted from Salacia crassifolia and its molecular architecture and supramolecular arrangement were characterized by X‐ray diffraction and Hirshfeld Surface. Theoretical calculations such as QTAIM, frontier molecular orbital, MEP and infrared spectra assignments were calculated at M06‐2X/6‐311++G(d,p) basis set. MEP revealed most positive region around hydrogen atoms of the hydroxyl group. X‐ray diffraction and QTAIM results showed that EPC forms a tetramer linked by classical hydrogen bonds O–H…O due to the number of hydroxyl groups available. The crystalline packing and supramolecular arrangement are stabilized by non‐classical hydrogen C–H…O and C–H…π interactions.
Aloe vivipara(Asphodelaceae s.l.): Nomenclature, history, and typification of a complicated Linnaean name
Authors: Iamonico Duilio , García‐Morales Leccinium J. 
Published: December 2019

AbstractThe typification of the Linnaean nameAloe viviparais discussed. The illustration in Rumphius'sHerbarium Amboinenseis designated as the lectotype. The nomenclatural history ofAl. viviparaand related names is presented. Among them,Agave candelabrum(=Al. vivipara) is lectotypified on an illustration from Todaro.Aloe viviparais considered a heterotypic synonym ofAgave vivipara, the latter name having nomenclatural priority.Agave cantalais neotypified on Wight's illustration, and synonymized withAg. wightii(=Ag. angustifolia), which is lectotypified on Wight's specimen at E.
What is mindreading?
Authors: Spaulding Shannon 
Published: December 2019

AbstractTheory of mind, also known as mindreading, refers to our ability to attribute mental states to agents in order to make sense of and interact with other agents. Recently, theorists in this literature have advanced a broad conception of mindreading. In particular, psychologists and philosophers have examined how we attribute knowledge, intention, mentalistically loaded stereotypes, and personality traits to others. Moreover, the diversity of our goals in a social interaction—precision, efficiency, self/in‐group protection—generates diversity in the mindreading processes we employ. Finally, the products of mindreading are varied, as well. We produce different sorts of mindreading explanations depending on our epistemic goals and the situational context. In this article, I piece together these different strands of research to present a broad conception of mindreading that is complex, messy, and interesting.This article is categorized under:Philosophy > Knowledge and BeliefPhilosophy > Psychological Capacities
Combined constant speed control method for a wind generator equipped with hydraulic energy storage
Authors: Han Xiaoxia , Wei Liejiang , Feng Yongbao , Wang Gang , Liu Zengguang , Xie Jian 
Published: December 2019

AbstractA wind generator equipped with hydraulic energy storage (WG‐HES) uses hydraulic transmission systems instead of gearbox transmissions, thus eliminating high‐power converters and reducing the tower‐top cabin weight. When there is no wind or the wind speed is extremely low, the pressured oil released by accumulators is used to drive a motor to operate at a constant speed, thereby generating constant‐frequency power. However, few studies have examined the constant speed control characteristics for generating electricity using only an accumulator group. In this study, a combined constant speed (CCS) proportional–integral–derivative (PID) control method based on “variable displacement and throttling” is proposed, which includes two closed loops and one regulating loop. First, a simulation model of the CCS PID control method for a variable motor was established in the Simcenter Amesim program. The influence of different PID parameters on the anti‐interference ability of the constant speed control of the motor was analyzed under a given load step. Then, we obtained the range of control parameter values and a set of optimal values. Second, the effectiveness of the CCS control method and the accuracy of the simulation results were verified on a 600‐kW WG‐HES system prototype. The results verified that the CCS control method has good anti‐interference ability and can meet the requirements of constant speed control for a variable motor under the best PID parameters. These results can provide a basis for developing control strategies for WG‐HESs when there is no wind or at low wind speeds.
The effect of exercise on aromatase inhibitor-induced musculoskeletal symptoms in breast cancer survivors :a systematic review and meta-analysis
Authors: Lu Geling , Zheng Jin , Zhang Lei 
Published: December 2019

Abstract
Background
Evidence is mixed regarding the effect of exercise programs on improving musculoskeletal symptoms and quality of life. Previous meta-analyses have not focused specifically on the musculoskeletal symptoms. Therefore, this meta-analysis aimed to evaluate the effect of exercise on these outcomes in breast cancer survivors taking aromatase inhibitors.

Methods
PubMed, CINAHL, EMBASE, Web of Science, Wan Fang, CNKI, VIP, and CBM were searched for randomized control trials or quasi-experimental studies from the establishment of the database to May 2019. Studies comparing exercise programs with usual care among breast cancer survivors taking aromatase inhibitors were included. The primary outcome was the degree of musculoskeletal symptoms, as assessed by scores of pain, stiffness, and grip strength. The secondary outcome was the total quality of life score.

Results
A total of 9 studies involving 743 participants were included. Exercise programs were more effective than usual care in improving musculoskeletal symptoms among breast cancer patients taking AIs. The subgroup scores of pain (SMD = -0.46, 95% CI -0.79 to -0.13, P = 0.006), stiffness (SMD = -0.40, 95% CI -0.71 to -0.08, P = 0.01), and grip strength (SMD = 0.43, 95% CI 0.16 to 0.71, P = 0.002) benefited from exercise interventions. Similar effects were found for the quality of life scores (SMD = 2.24, 95% CI 0.28 to 4.21, P = 0.03).

Conclusions
Results indicate that exercise relieves musculoskeletal symptoms and improves quality of life, which can be used to motivate patients to exercise actively under professional guidance. Due to a small sample size, further research is required to ensure the effectiveness of exercise on musculoskeletal symptoms and quality of life.
Coronary artery disease risk reclassification using an acoustic-based score in view of the new European Society of Cardiology 2019 guidelines on Chronic Coronary Syndromes
Authors: Schmidt S. E. , Winther S. , Boettcher M. 
Published: December 2019

AbstractIn August 2019, ESC published new guidelines on Chronic Coronary Syndromes including a new risk assessment paradigm for estimation of pre-test-probability. The CAD-score is an acoustic-based score for ruling-out of coronary artery disease (CAD). In the current letter to the editor we re-evaluate the re-classification potential the CAD-score in the view of the new guidelines.
Peering Forward, 10 Years After: International Policy and Consumer Credit Regulation
Authors: Ramsay I. , Williams T. 
Published: December 2019

AbstractA key change since the financial crisis of 2008 is the internationalization of interest in consumer finance. International institutions monitor household credit because of its impact on financial stability and market expansion. Macroprudential concerns drove this interest, resulting in a sea change in approaches to consumer credit regulation in many jurisdictions. This article critically analyses the emerging international policy paradigm, contrasting pre-and post-crisis regulatory approaches and highlighting continuing tensions about key policy choices. It then uses two recent sites of contestation, debt adjustment and the regulation of high-cost credit to demostrate the persistence of conflict over the positioning of consumers within an emergent stability focused paradigm of financial consumer protection.
Nepali Migrant Workers and the Need for Pre-departure Training on Mental Health: A Qualitative Study
Authors: Regmi Pramod R. , Aryal Nirmal , van Teijlingen Edwin , Simkhada Padam , Adhikary Pratik 
Published: December 2019

AbstractEvery year around 1000 Nepali migrant workers die abroad. Every one in three females and one in ten males commit suicide, reflecting a high mental health risk among Nepali migrant workers. This study aims to identify triggers of mental ill-health among Nepali migrant workers and their perceptions on the need of mental health components in the pre-departure orientation programme. We conducted five focus group discussions (FGD) and seven in-depth interviews with Nepali migrant workers and eight semi-structured interviews with stakeholders working for migrants. Participants were invited at Kathmandu’s international airport on return from abroad, at hotels or bus stations near the airport, through organisations working for migrants, and participants’ network. All FGD and interviews were conducted in Kathmandu and audio recorded, transcribed and translated into English. Data were analyzed thematically. High expectations from families back home, an unfair treatment at work, poor arrangements of accommodation, loneliness and poor social life abroad were frequently reported factors for poor mental health. Access to mental health services abroad by Nepali migrant was also poor. We found little on mental health in the pre-departure orientation. We need to improve our knowledge of mental health risks to provide better, more focused and more up-to-date pre-departure training to new migrant workers leaving Nepal.
Distributed block-diagonal approximation methods for regularized empirical risk minimization
Authors: Lee Ching-pei , Chang Kai-Wei 
Published: December 2019

AbstractIn recent years, there is a growing need to train machine learning models on a huge volume of data. Therefore, designing efficient distributed optimization algorithms for empirical risk minimization (ERM) has become an active and challenging research topic. In this paper, we propose a flexible framework for distributed ERM training through solving the dual problem, which provides a unified description and comparison of existing methods. Our approach requires only approximate solutions of the sub-problems involved in the optimization process, and is versatile to be applied on many large-scale machine learning problems including classification, regression, and structured prediction. We show that our framework enjoys global linear convergence for a broad class of non-strongly-convex problems, and some specific choices of the sub-problems can even achieve much faster convergence than existing approaches by a refined analysis. This improved convergence rate is also reflected in the superior empirical performance of our method.
Mathematical Optimization Problems for Particle Finite Element Analysis Applied to 2D Landslide Modeling
Authors: Wang Liang , Zhang Xue , Zaniboni Filippo , Oñate Eugenio , Tinti Stefano 
Published: December 2019

AbstractNotwithstanding its complexity in terms of numerical implementation and limitations in coping with problems involving extreme deformation, the finite element method (FEM) offers the advantage of solving complicated mathematical problems with diverse boundary conditions. Recently, a version of the particle finite element method (PFEM) was proposed for analyzing large-deformation problems. In this version of the PFEM, the finite element formulation, which was recast as a standard optimization problem and resolved efficiently using advanced optimization engines, was adopted for incremental analysis whilst the idea of particle approaches was employed to tackle mesh issues resulting from the large deformations. In this paper, the numerical implementation of this version of PFEM is detailed, revealing some key numerical aspects that are distinct from the conventional FEM, such as the solution strategy, imposition of displacement boundary conditions, and treatment of contacts. Additionally, the correctness and robustness of this version of PFEM in conducting failure and post-failure analyses of landslides are demonstrated via a stability analysis of a typical slope and a case study on the 2008 Tangjiashan landslide, China. Comparative studies between the results of the PFEM simulations and available data are performed qualitatively as well as quantitatively.