bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survival Outcomes of Laparoscopic Pancreaticoduodenectomy with Arterial Circumferential Lymphadenectomy and Total Meso-pancreas Dissection for Periampullary Malignancies
Authors: NGUYEN Ham Hoi , NGUYEN Thanh Khiem , LUONG Tuan Hiep , TRINH Hong Son , NGUYEN Dang Vung , LE Van Duy 
Published: December 2024

Abstract

Backgrounds.
The purpose of this study is to evaluate the survival outcomes, recurrence pattern and risk factors of patients with resectable periampullary malignancies (PM) underwent laparoscopic pancreaticoduodenectomy (LPD) with left-sided superior mesenteric artery (SMA) first-approach, circumferential lymphadenectomy around SMA and common hepatic artery (CHA) combined total meso-pancreas dissection (TMpD).
Methods.
This prospective study included 37 patients who underwent LPD for resectable PMs. General characteristics, operative techniques, pathological results, and survival outcomes including recurrence pattern were prospectively evaluated.
Results.
The median age of 58,95 ± 8,9 years (range 35–70), with fifty-four-point one percent of the patients are aged over 60 years. The mean operative time was totally 426,2 ± 78,5 (250–600) minutes. Metastatic meso-pancreas was observed in 11 cases (29,7%), and 17 cases (45,9%) had reactive fibrous tissue. The number of harvested lymph nodes (LNs) and left-sided SMA LNs were 32,4 ± 12,2 (16–74) and 7,1 ± 5,6 (1–30), respectively. The rate of metastatic left sided SMA LNs was 5 cases (13,5%). In multivariate analysis, the left sided SMA LNs metastasis status was the sole significant factor of both DFS and OS (p < 0.1).
Conclusion.
LPD with left-sided SMA first-approach, circumferential lymphadenectomy around SMA and CHA combined TMpD was effective to achieve favorable oncological and survival outcomes.
Examining the Level of College Students’ Awareness Regarding the Healing Function of Art Therapy as an Intervention for the Psychological Development of College Students in China
Authors: Guangli Luo 
Published: December 2024

Abstract

The aim of this study is to examine the level of college students’ awareness regarding the healing functions of art therapy as an intervention for the psychological development of college students in China. Numerous studies have explained the different healing benefits of art therapy to different people all over the world in recent times. This study specifically focuses on three main functions of art therapy for a specific group of individuals-college students in China. The study is anchored on the healing value of art in modern design as identified by (14) and the Functions of Expressive Arts Therapy proposed by Malchiodi. The theoretical framework integrates these two approaches to maximize the healing value of art by combining psychological cues, self-awareness enhancement, and the expressive arts therapy methods. The research is a quantitative descriptive study aimed at determining the level of students’ awareness regarding the healing function of arts for the psychological development of college students. The study data were obtained via questionnaire filled online by the research participants. The research population was students from five schools (SCBC, GMU, BNU, CCOM and SHCM) selected in China, from whom a sample size of 352 was drawn. The questionnaire filled and completed was analysed using SPSS. The study results revealed that there was high level of students’ awareness in all the variables (guide to recognize and explore oneself, healing and appreciating oneself, and unconscious spiritual healing). Based on the study’s findings, the researcher proposed a sustainable art therapy program that can enhance the awareness level of college students regarding the healing benefits of art therapy.
parafac4microbiome: Exploratory analysis of longitudinal microbiome data using Parallel Factor Analysis
Authors: Ploeg Geert Roelof van der , Westerhuis Johan A. , Heintz-Buschart Anna , Smilde Age K. 
Published: December 2024

Abstract

Background: Recently, studies that investigate microbial temporal dynamics have become more frequent. In a longitudinal microbiome study design, microbial abundance data are collected across multiple time points from the same subjects. In this context, exploratory analysis of longitudinal microbiome data using Principal Component Analysis is insufficient because the study design is not fully utilized. Indeed, the study design can be used to create a three-way data array where the rows constitute the subjects, the columns contain the microbial abundances, and the third dimension contains the time points. Organising the data this way enables multi-way methodologies that take full advantage of the study design. In this work we present Parallel Factor Analysis (PARAFAC) as a method to explore longitudinal microbiome data using three exemplary studies.
Results: In the first example study, a long time series of experimental in vitro microbiomes, we show that PARAFAC can identify the main time-resolved variation in longitudinal microbiome data. In the second example, a longitudinal infant gut microbiome study, we show that PARAFAC can find differences between subject groups and enhance comparative analysis despite a moderate amount of missing data. In the third example, a longitudinal gingivitis intervention study of the oral microbiome, we show that PARAFAC helps identify microbial groups of interest using a post-hoc clustering approach.
Conclusions: We show that Parallel Factor Analysis is an applicable method for longitudinal microbiome data analysis across a wide range of microbial environments. The analyses and the example datasets with the resulting figures are implemented in the R package parafac4microbiome, which is available on CRAN at https://cran.rstudio.com/web/packages/parafac4microbiome/.
A hidden danger: Lung abscess following inhalation of kerosene-based pyrethroid insecticide spray
Authors: Ofune Kohei , Hirose Tomoya , Kai Hiroki , Yokono Yoshinori , Takegawa Ryosuke , Oda Jun 
Published: December 2024

Abstract

Background Pyrethroid insecticides are widely used because of their low toxicity in humans. Spray-type pyrethroids are often formulated with kerosene as a carrier solvent, and inhalation of kerosene-containing products can lead to pneumonia and the formation of lung abscesses. We report a case of chemical pneumonia resulting in the development of a lung abscess due to the intentional inhalation of pyrethroids.
Case presentation A man in his 50s in a psychiatric hospital for transient psychotic disorder attempted suicide during an overnight leave from the hospital. He drank sodium hypochlorite, put a nylon bag over his head, and sprayed pyrethroid insecticide inside the bag. He was found collapsed and was transported to our emergency room. On arrival, his SpO2 was 100% (on O2 at 10 L/min by mask), his circulation was stable, and his Glasgow Coma Scale score was E1V3M6, which improved to E4V5M6 in about one hour. A chest computed tomography (CT) scan showed ground-glass shading in both lungs. We diagnosed him as having pneumonia and started antimicrobial therapy. On day 13 of hospitalization, we found multifocal hypo-absorptive areas, and a diagnosis of lung abscess was made based on CT imaging, and antimicrobial therapy was continued. During the hospitalization, he expectorated bloody sputum. A contrast chest CT scan obtained on day 71 of hospitalization showed a pseudoaneurysm in the abscess cavity, for which we performed successful transcatheter coil embolization. On day 77, the abscess was shrinking, and he was transferred to another hospital for continued treatment. However, he again had bloody sputum and was transferred back to our hospital on day 113. Another contrast chest CT scan revealed the formation of a new aneurysm, and on day 114, we successfully performed coil embolization again, and he was transferred back to the other hospital on day 116.
Conclusions Spray-type pyrethroid insecticides contain the organic solvent kerosene. Inhalation of kerosene has been reported in several cases of chemical pneumonitis leading to lung abscess. Clinicians should pay attention to kerosene contained in insecticides and the circumstances under which they are used. Early recognition and aggressive treatment can likely prevent severe outcomes.
Risk Factors and Mortality in Children with Severe Pertussis: The Role of Exchange Transfusion
Authors: Huo Junming , Chen Song , Qin Yanran , Xu Feng , Liu Chenjun 
Published: December 2024

Abstract

Objective
High white blood cell (WBC) counts has been identified as a risk factor for adverse outcomes in pertussis patients, but the predictive value of it and the efficacy of interventions such as exchange transfusion remain poorly understood. Therefore, we endeavored to investigate the impact of white blood cell counts on mortality risk in severe pertussis children and assess the potential benefits of exchange transfusion therapy.
Methods
A retrospective analysis of 170 pertussis patients admitted to the Pediatric Intensive Care Unit (PICU) between January 2018 and June 2024 was performed.
Results
Among the 170 patients, 38 (22.35%) died. The deceased group exhibited significantly higher WBC counts (67.31 vs. 28.41 × 10^9/L, P < 0.001), neutrophils (29.95 vs. 11.61 × 10^9/L, P < 0.001), and C-reactive protein (CRP) (29 vs. 8 mg/L, P < 0.001). Additionally, sepsis (39.47% vs. 9.09%, P < 0.001), shock (63.16% vs. 6.06%, P < 0.001), ARDS (23.68% vs. 2.27%, P < 0.001), and acute kidney injury (21.05% vs. 0.76%, P < 0.001) were more prevalent in the deceased group. ROC analysis showed that WBC counts had a predictive value for mortality (AUC = 0.75, sensitivity = 0.78, specificity = 0.68), with an optimal cutoff of 48.58 × 10^9/L.
Conclusion
High WBC counts are significantly associated with an increased risk of mortality in critically ill children, with a threshold of 48.58 × 10^9/L identified as indicative of high risk. Exchange transfusion can reduce white blood cell counts, but patients with severe secondary infections still face a high risk of death after blood exchange.
Applying novel Plasmodium vivax serological exposure markers to quantify residual malaria transmission in the Philippines through repeated health facility surveys: the SMaRT study protocol
Authors: Bernal Jhobert , Macalinao Maria Lourdes , Cosca Katherine , Boncayao Beaulah , Mueller Ivo , Espino Fe Esperanza J. , Stresman Gillian , Luchavez Jennifer , Longley Rhea J. 
Published: December 2024

Abstract

Background
After decades of progress towards malaria elimination, Plasmodium vivax is now the predominant source of infection and the major obstacle towards elimination in the Asia-Pacific region. In the Philippines, the situation is slightly different with P. falciparum still accounting for the largest burden. However, there has been a steady increase in the total number of reported P. vivax cases in the main transmission hotspot of Palawan, as well as two years of consecutive outbreaks of P. vivax in the near-elimination setting of Sultan Kudarat. Here, we describe the protocol for a new study in Sultan Kudarat that aims to identify whether an underlying, hidden, burden of P. vivax contributes to the ongoing risk of outbreaks.
Methods
A challenge for surveillance of P. vivax is the presence of an additional hidden liver-stage, where parasites (hypnozoites) lie dormant for weeks to months before causing a relapse of infection. Hypnozoites cannot be detected with commercial diagnostic tests. We have designed novel serological exposure markers of recent P. vivax infection, which indirectly inform on hypnozoite carriage. In this study we will conduct a prospective 18-month survey in health facilities within Kalamansig, Sultan Kudarat, and compare epidemiology and serological data with that in archival samples from Palawan. We will enroll both care-seeking individuals and their companions, and utilise remote geolocation to uncover spatial trends.
Discussion
This study will generate important data for the malaria control program in the Philippines whilst also demonstrating utility of P. vivax serological exposure markers in near-elimination settings. We will utilise this data to build a decision-making framework to support novel, evidence-based elimination strategies relevant for the Philippines and the wider Asia-Pacific region.
Comparative analysis of thoracoscopic sympathetic nerve resection segments on clinical outcomes and quality of life in palmar hyperhidrosis patients
Authors: Wang Jingsi , Zhao Shengliang , Tang Bo , Xiang Mingzhang , Dai Jigang , Liu Quanxing 
Published: December 2024

Abstract

Background：Primary hyperhidrosis, characterized by excessive palm sweating, significantly impacts the quality of life for affected individuals, particularly among young adults. This study aimed to evaluate the efficacy of video-assisted thoracoscopic sympathectomy (VATS) in improving symptoms and quality of life among 816 patients with primary hyperhidrosis.
Methods：This retrospective study analyzed clinical data from 816 PPH patients treated at the Department of Thoracic Surgery, Second Affiliated Hospital of Army Medical University, between January 2014 and January 2024.
Results：The results indicated that the cohort consisted of 359 males and 457 females, with a mean age of 24.98 ±6.47 years. All patients underwent VATS, with a 100% success rate, and the mean operative time was 53.2 ±24.7 minutes. Postoperatively, complications included 43 cases of incision infections, 194 cases of chest pain, and 157 cases of pneumothorax; compensatory hyperhidrosis (CH) occurred in 53.80% of the T3 group and 43.74% of the T4 group after one month, with significant differences noted at the 24-month follow-up. Furthermore, QOL scores significantly improved from 38.25 ±3.61 preoperatively to 69.07 ±3.48 at one year postoperatively (P < 0.05).
Conclusions：VATS offers a reliable and effective treatment for severe palmoplantar hyperhidrosis, significantly enhancing patients' overall quality of life. Future research should focus on long-term outcomes and the applicability of this treatment across diverse populations to further advance clinical management of hyperhidrosis.
Effect of game-based physical education interventions on executive function, attention and academic performance in children: a systematic review and meta-analysis from 2010 to date
Authors: Mo Weilong , Saibon Jamalsafri Bin , Li Yaming , Deng Shuao , Li Jiequan , He Yanwu 
Published: December 2024

Abstract

Background
Previous studies found that gamification interventions have a positive impact on children's cognitive functioning and academic performance. However, implementation of gamification interventions in physical education has been limited over the past two decades, This research aimed to analyse the impact of game-based physical education on executive function, attention, and academic performance in children.
Methods
This research was conducted with six electronic databases: Web of Science, PubMed, EBSCOhost, Cochrane, Embase, and Scopus, covering the span of time from 2010 to September 2024. This meta-analysis evaluated the impact of game-based PE intervention on executive function, attention, and academic performance in children through both randomized controlled trials (RCT) and non-randomized controlled trials (nRCTs). From an initial pool of 343 studies identified, 167 were independently reviewed by two authors. 15 studies met the inclusion criteria and were included in the meta-analysis. The quality of these studies was assessed using the Effective Public Health Practice Project (EPHPP) tool.
Results
Meta-analysis revealed significant moderate effects across three main domains: executive function (SMD = 0.72, 95% CI: [0.33, 1.10], p = 0.0002), attention (SMD = 0.50, 95% CI: [0.22, 0.79], p = 0.0006), and academic performance (SMD = 0.59, 95% CI: [0.28, 0.91], p = 0.0002). Within executive function, cognitive flexibility (SMD = 1.10, 95% CI: [0.71, 1.30], p < 0.0006) and response inhibition (SMD = 0.77, 95% CI: [0.58, 0.97], p < 0.00001) showed significant improvements, while working memory did not (SMD = 0.25, 95% CI [-0.11, 0.62], p = 0.18). No significant effects were found in selective attention (SMD = -0.07, 95% CI [-0.59, 0.46], p = 0.80) or sustained attention (SMD = 0.03, 95% CI [-0.49, 0.55], p = 0.91). For academic performance, only mathematical ability showed significant improvement (SMD = 0.56, 95% CI [0.19, 0.94], p = 0.003).
Conclusions
Game-based interventions have shown effective in enhancing executive function, attention and academic achievement in children.
Do diesel exhaust particles affect the flight activity of the buff-tailed bumblebee Bombus terrestris in the field?
Authors: Seidenath Dimitri , Pölloth Sarah , Mittereder Andreas , Hillenbrand Thomas , Brüggemann Dieter , Schott Matthias , Laforsch Christian , Otti Oliver , Feldhaar Heike 
Published: December 2024

Abstract

The loss of insect biodiversity and biomass is threatening ecosystems around the globe. Drivers of this insect decline include climate change, habitat degradation and pollution. Exposure to airborne particulate matter, such as diesel exhaust particles, may be harmful, especially for insects around urban or industrial areas. Ecotoxicological experiments have shown that chronic oral uptake of diesel exhaust particles can result in higher mortality and changes in the gut microbiome. But how such effects manifest in a natural setting are still largely unknown, especially their effect on the foraging activity and behavior. Here, we exposed workers of the bumblebee Bombus terrestris to diesel exhaust particles and evaluated their impact on the flight activity, i.e. the homing flight and subsequent foraging activity, in the field. We observed a significant delay in the starting time of the bumblebees treated with diesel exhaust particles after the release caused by the inability of some workers to take off vertically from of the exposure box and grooming behavior. Homing flight and subsequent foraging activity did not differ between the treatments. Our findings provide new insights into the potential role of airborne particulate matter in the insect decline by impairing flight activity. However, it remains unclear why bumblebees struggle to start a take-off vertically after exposure to diesel exhaust particles. This observation needs further investigation to elucidate, for example, if this behavior may indicate underlying physiological constraints.
Face and Content Validation of the 10-item Communicative Participation Item Bank for Primary Progressive Aphasia: A Cognitive Interviewing Study
Authors: Fegter Ollie , Shaunfield Sara , Bona Matthew , Cummings Emily , Roberts Angela , Rogalski Emily 
Published: December 2024

Abstract

Background
Primary Progressive Aphasia (PPA) is a clinical neurodegenerative dementia syndrome marked by progressive decline in language skills, which profoundly affects communication participation in daily life. The 10-item short form of the Communicative Participation Item Bank (CPIB) is a self-report measure developed to assess communicative participation across everyday communication situations and activities. Developed as a disorder-agnostic measure, the appropriateness of the CPIB for capturing clinically meaningful communication function for individuals with PPA has not yet been evaluated but is important for assessing impact of PPA as well as the development and assessment of interventions. Cognitive interviewing was used to evaluate the face and content validity of the CPIB for persons with PPA and their communication partners.
Methods
Nine dyads, each consisting of a person with PPA and their communication partner, completed semi-structured cognitive interviews that assessed the instructions, format, response options, item comprehension, and relevance to their experiences with PPA. Interviews were conducted via videoconference. Closed-ended responses were quantified and open-ended responses were analyzed via thematic analysis. Summaries were generated for each item, including recommended changes.
Results
Measure instructions and format were clear to all participants (N = 18; 100%). Participants demonstrated good comprehension of individual CPIB items, with a majority finding the items clear and relevant to their experiences. Most (n = 14; 78%) participants suggested adding a fifth response option (i.e., “Somewhat”) to better capture their range of communication experiences. Talking on the phone was the most reported missing communication participation situation (n = 12; 67%), followed by videoconference (n = 3; 17%) and email/texting (n = 3; 17%).
Conclusions
Initial data support use of the CPIB with persons with PPA and their communication partners for capturing clinically meaningful communication function. Potential modifications for sharpening the relevance, applicability, and sensitivity to longitudinal measurement of change include increasing number the number of response levels, adding an item on communication participation via phone/videochat, and using proctored administration for persons with PPA.
Enhanced Image Satellite Classification by Using Stacked Learning Model (SLM)
Authors: Darghaoth Ahmed M.H. , Anaz Ammar Sameer , Al-Nima Raid Rafi Omar 
Published: December 2024

Abstract

One of the common challenges in image satellite classification prediction models is obtaining high accuracy, and from this perspective, the primary objective of this paper is to implement the Stacked Learning Model (SLM) technique with the aim of enhancing the accuracy of image classification. Academic research and practical applications have widely used the suggested model, which has made significant strides in the field of image classification. By using a SLM, the model combined the results of three base models to improve the predictive ability and accuracy of image classification. This approach had been applied in a series of sequential steps designed to improve the performance of individual models and their integration. The proposed model uses the EuroSat dataset, which includes images. These images are of high resolution and cover various land use and land cover classes across Europe. They have been evenly distributed across six classes: residential, permanent crop, pasture, industrial, highway, and forest. This data has been augmented to reduce the problem of overfitting and improve the model’s ability to generalize. The model achieved a classification accuracy of 92.35% after training, confirming its robustness in image classification applications, particularly in areas where accuracy is crucial. Various comparisons, even with state-of-the-art models, will be provided.