bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infrastructural, performative and feral: Understanding agri‐environmental data relations in Aotearoa New Zealand
Authors: Edwards Sarah , Henry Matthew , Rosin Christopher 
Published: February 2025

AbstractIn agri‐environmental decision‐making, data are essential to defining problems and informing solutions. Nevertheless, it is important to consider not only how data can be used but also what data does in agri‐environmental contexts. We argue that the liveliness of data relations can be explored by attending to their infrastructural, performative and feral qualities. Taking digital agriculture and climate change adaptation as examples, we also consider how these interconnected theses could be applied. This critical approach to data relations and their generative effects will help avoid unintended consequences and shape alternative agri‐environmental futures.
Extensive Maxillary Defect and Oroantral Fistula Resulting From Medication‐Induced Osteonecrosis in a Patient Undergoing Oral Surgery
Authors: Marenucci Naellen Rampazzo , Sandoval Lara Gabriela Da Silva Barbosa , Costa Bruna da Silva , Rodrigues Kathiussa Fernanda Parreira , Bachesk Andressa Bolognesi 
Published: February 2025

ABSTRACTOsteonecrosis of the jaws is a severe condition associated with the use of anti‐resorptive therapies, such as bisphosphonates, which inhibit osteoclast activity and diminish bone repair capacity. Although the risk of osteonecrosis is generally low in patients undergoing oral administration of these medications, the potential for complications remains. A lack of awareness among dental surgeons about this condition often leads to the performance of surgical procedures without adequate pre‐ and post‐operative care, potentially resulting in significant complications and serious long‐term consequences.AimThis work aims to report a case of a patient undergoing treatment with bisphosphonates who faced post‐surgical complications after surgical procedures performed without the appropriate care.MethodsThe patient, a 73‐year‐old woman, underwent tooth extractions and dental implant removal while being on sodium alendronate therapy for 2 years. She developed maxillary sinusitis associated with an oroantral fistula and suffered severe loss of a significant portion of her left maxilla.Results and ConclusionFor case management, surgical and conservative approaches were employed, including surgical debridement, flap creation for oroantral fistula closure, laser therapy, antibiotic treatment and the combination of a medication protocol with pentoxifylline and tocopherol. This underscores the importance of dental surgeons having comprehensive knowledge of osteonecrosis of the jaws and being equipped to manage these cases effectively, considering both clinical treatment strategies and the potential prevention of complications.
Critical Race Theory in Theological Education
Authors: Fears Barbara A. 
Published: February 2025

ABSTRACTBoth the history of and the changing demographics within theological education demand a reckoning with the past, a close examination of the present, and a course correction for the future. Critical race theory (CRT), a framework currently under fierce political debate and intense public scrutiny, provides a lens for such a task. CRT is a misrepresented and misunderstood analytical tool that began in the field of law but has since spread to other disciplines including education and theology to study disparities across racial, religious, and gender lines. Although there is no canonical set of beliefs to which all CR theorists subscribe, in general, liberalism, claims of neutrality, objectivity, meritocracy, and colorblindness are rejected. Herein, I argue for the rejection of liberalism in theological education and offer recommendations to counter liberal tendencies in teaching, research, and service in the field.
A procedure using low‐cost reagents to prepare allogeneic platelet gel from standard platelet units
Authors: Mykhailova Larysa , Calvo Javier , Gafou Anthi , Garcìa Erce Josè Antonio , Lydaki Evangelia , Schinocca Maria Elena , Samarkanova Dinara , Scimemi Gabriele , Montemurro Tiziana 
Published: February 2025

AbstractBackground and ObjectivesHighly effective procedures for the preparation of allogeneic platelet gel (PG) use Ca‐gluconate and batroxobin, an expensive commercial reagent. In this preliminary study, we explored the use of the plasmin‐inhibitor, low‐cost drug tranexamic acid (TXA) in place of batroxobin, based on the literature supporting TXA ability to prevent fibrinolysis and stabilize the gel formed by fibrin polymerization prompted by Ca‐gluconate.Materials and MethodsEight blood centres determined PG weight and volume of non‐gelled, liquid portion in 116 PG prepared in 20‐mL commercial BioNest D bags. Ten‐millilitre platelet aliquots from platelets in 100% plasma or in 35% plasma/65% platelet additive solution (PAS) were aseptically transferred into the D bag, followed by the injection of 3.3 mL of 10% Ca‐gluconate and 0.4 mL of TXA. After 30‐min incubation, PG weight and non‐gelled liquid volume were determined.ResultsPG weight and liquid volume at 30 min were 6.5 ± 3.4 g and 7.4 ± 3.5 mL with platelets in 100% plasma, and 3.7 ± 3.0 g and 10.2 ± 3.3 mL with PAS platelets, respectively.ConclusionThis study provides preliminary evidence supporting the use of TXA as a low‐cost reagent for PG manufacturing from platelets in 100% plasma.
Combining Ultrasonic Pulse Velocity and Non-Linear Ultrasonic Techniques to Assess Concrete Strength
Authors: Alnuaimi Hamad , Amjad Umar , Alnuaimi Yousef , Kundu Tribikram 
Published: February 2025

Abstract
Non-Linear Ultrasonics (NLU) has grown in importance over the past years. The viability of applying the newly developed NLU technique called the Sideband Peak Count-Index (SPC-I) to estimate the 28-day unconfined compressive strength (UCS) of cylindrical concrete specimens is investigated. In addition, the SPC-I technique is combined with the conventional Ultrasonic Pulse Velocity (UPV) technique to achieve more precise UCS estimations than would be possible with a single estimation parameter. 16 conventional general purpose concrete specimens are cast utilizing Water-to-Cement (W/C) ratios of 0.4, 0.5, 0.55, and 0.6. To ensure reproducibility of results, experimental operations are performed utilizing consistent testing protocols and instruments. The SPC-I is determined to be a viable parameter that can be used to estimate the UCS value of concrete specimens with high accuracy. In addition, when the SPC-I is combined with the UPV, the resulting estimates become even more accurate and reliable than when utilizing only UPV values.
Opioid-free versus opioid-based anaesthesia for free-flap reconstruction surgery of the breast: protocol for a phase III, multicentre, randomised controlled study
Authors: Saad-Boutry Mary , Carton Matthieu , Ezzili Cyrine , Savignoni Alexia 
Published: February 2025

IntroductionEfforts have focused in recent decades on developing anaesthetic strategies that limit the use of morphine because of its known side effects. This study aims to compare postoperative morphine consumption between opioid-free anaesthesia (OFA) and conventional opioid-based general anaesthesia.Methods and analysisPhase III, multicentre, randomised controlled study comparing morphine consumption in the immediate postoperative period (first 48 hours) between OFA and conventional general anaesthesia (CGA). The study is conducted across three French academic cancer centres, with a planned enrolment of 158 patients, randomly assigned (1:1) to the OFA and CGA. The primary outcome is morphine consumption during the first 48 hours postoperatively.Ethics and disseminationThe study has been approved by the National Research Ethics Committee (CPP, reference number 1-22−036/22.01675.000085) and the French National Agency for Medicines and Health Products Safety (ANSM, reference number MEDAECNAT-2022-04-0057). Written, informed consent to participate will be obtained from all participants. Results will be published in international peer-reviewed journals.Trial registration numberThis trial has been registered in the Clinical Trials in the European Union database (CTIS number: 2024-513308-32-00) and in ClinicalTrials.gov (NCT05439005).
Association of nocturnal oxygen saturation with coronary artery calcification: cross-sectional evidence from the population-based SESSA study among Japanese men
Authors: Mondal Rajib , Takashima Naoyuki , Torii Sayuki , Harada Akiko , Mohd Azahar Nazar , Moniruzzaman Mohammad , Kondo Keiko , Kadowaki Sayaka , Kadota Aya , Yano Yuichiro , Ueshima Hirotsugu , Miura Katsuyuki 
Published: February 2025

ObjectiveWe investigated the associations of nocturnal oxygen saturation (SpO2) with prevalence of coronary artery calcification (CAC) and its level of burden, and whether the associations differ by obesity and mediate through diabetes mellitus (DM), dyslipidaemia and hypertension.DesignObservational study.SettingKusatsu, Shiga.ParticipantsWe analysed data from 510 Japanese men (aged 46–76 years) with no history of myocardial infarction.Primary and secondary outcomesMean SpO2, minimum SpO2and oxygen desaturation index (ODI) were measured using overnight pulse oximetry (primary exposures), while CAC was assessed using CT. Prevalence of CAC (>0) and its burden (CAC 0, >0–100, >100–400 and>400) were evaluated as outcomes. Body mass index≥25.0 kg/m2defined as obesity.ResultsMean±SD age was 66.7±7.2 years. The prevalence of CAC was 64.7% (CAC scores>0–100, 31.4%; >100–400, 20.0% and>400, 13.3%). In multivariable binary logistic regression, the OR and 95% CI for the prevalence of CAC were 1.25 (1.02 to 1.53) per 1-SD decrement in mean SpO2and 1.25 (1.01 to 1.55) per 1-SD increment in ODI. The associations lost their significance while further adjusted for DM and dyslipidaemia. Similar trends were observed for the level of CAC burden in multivariable ordinal logistic regression. Obesity did not show significant interaction with SpO2on CAC. In mediation analysis, the OR (95% CI) for natural indirect effect; percentage mediated through dyslipidaemia in association of 1-SD decrement in mean SpO2with prevalence of CAC were 1.06 (1.01 to 1.10); 25.4%. These estimates for mediation through DM and dyslipidaemia for 1-SD increment in ODI in the associations were 1.07 (1.01 to 1.12); 29.6% and 1.04 (1.00 to 1.08); 17.5%, respectively.ConclusionsLower mean SpO2and higher ODI are associated with CAC among Japanese men, independent of age, lifestyle factors and obesity. The associations became non-significant after adjusting for diabetes and dyslipidaemia, but were mediated through these factors.
Reducing prematurity-related neonatal mortality: a quality improvement project in Gandhi Memorial Hospital, Addis Ababa, Ethiopia
Authors: Wotango Biniam Yohannes , Workneh Wubet Mihretu , Abdana Tariku Deressa , Kidane Hailegebriel , Alemayehu Mahlet , Niku Dawit , Alene Birtukan , Aragaw Aynekulu , Belay Zafu , Adenew Tigist , Hailu Gebremeskel Tamene , Haile Yeneneh Getachew 
Published: February 2025

BackgroundNeonatal deaths refer to infants who die within the first 28 days of life, and they account for almost 50% of all child deaths under the age of 5 globally. Preterm birth is the primary reason for neonatal deaths, and it can lead to various complications that may prove fatal for newborns, such as respiratory distress syndrome, sepsis and intracranial haemorrhages. There was a high rate of neonatal mortality at Gandhi Memorial Hospital. 57.7% of neonatal deaths were caused by premature-related problems according to Pareto chart analysis. The baseline mortality rate among premature neonates admitted to the Neonatal Intensive Care Unit (NICU) was 20.7%. The objective of this quality improvement project was to reduce prematurity-related neonatal death at Gandhi Memorial Hospital.MethodsA multidisciplinary quality improvement team used a fishbone diagram to analyse the causes of neonatal deaths related to prematurity. We used the Institute for Healthcare Improvement (IHI) model for improvement, using Plan-Do-Study-Act cycles to measure progress and make data-driven decisions.InterventionsTransporting premature neonates born in the labour ward to NICU with CPAP, increasing the use of a continuous positive airway pressure (CPAP) device with an integrated oxygen concentrator, blender and compressor, and implementing the infection prevention checklist with four components were the implemented change ideas.ResultsThe run chart showed a 25.6% reduction in prematurity-related neonatal mortality after implementing three interventions, and evidenced by a shift below the baseline median.Conclusion and recommendationThe quality improvement project involving three interventions which are transporting premature neonates from labour ward to NICU with CPAP, using a CPAP device with an integrated oxygen concentrator, blender and compressor for preterm neonates and infection prevention checklist use with four components at Gandhi Memorial Hospital effectively reduced prematurity-related neonatal death. To improve neonatal outcome in premature neonates, we recommend that hospitals should prioritise implementing a standardised CPAP transport protocol, increasing a CPAP device with an integrated oxygen concentrator, blender and compressor use in the NICU, and fully implementing the infection prevention Checklist.
Predictors of early disability accumulation in newly diagnosed multiple sclerosis: clinical, imaging and cerebrospinal fluid measures
Authors: Lauerer Markus , Wiltgen Tun , Brückner Carolin , Engl Christina , Giglhuber Katrin , Lambrecht Sebastian , Pongratz Viola , Berthele Achim , Gasperi Christiane , Kirschke Jan S , Zimmer Claus , Hemmer Bernhard , Mühlau Mark 
Published: February 2025

BackgroundA growing arsenal of treatment options for relapsing multiple sclerosis (RMS) emphasises the need for early prognostic biomarkers. While evidence for individual markers exists, comprehensive analyses at the time of diagnosis are sparse.MethodsBrain and spinal cord lesion numbers, cerebrospinal fluid parameters, initial symptoms, and Expanded Disability Status Scale (EDSS) score were determined at the time of diagnosis. Confirmed disability accumulation (CDA), defined as a sustained EDSS increase over 6 months, was determined during a 5-year follow-up. All-subsets multivariable logistic regression was performed to identify predictors of CDA. Model performance was assessed via receiver operating characteristic analysis, and individual risks were calculated. Analyses were repeated with progression independent of relapse activity (PIRA) as an outcome.Results113/417 (27.1%) people with RMS experienced CDA on follow-up. Intrathecal IgG synthesis, a higher number of spinal cord lesions, age and polysymptomatic manifestation were identified as independent predictors of CDA. The resulting prediction model yielded an area under the curve (AUC) of 0.75 with a 95% CI of 0.70 to 0.80. Individuals exceeding the optimal thresholds for the three most significant predictors had a 61.8% likelihood of experiencing CDA, whereas those below all three thresholds had a CDA rate of 4.5%. The only significant baseline predictor differentiating PIRA from relapse-associated worsening was a higher number of spinal cord lesions (AUC=0.64, 95% CI 0.54 to 0.74).ConclusionsIntrathecal IgG synthesis, spinal cord lesion number, age and polysymptomatic manifestation are independent predictors of early CDA in newly diagnosed RMS.
Microcosting analysis of percutaneous coronary intervention with and without intracoronary imaging in an Irish tertiary referral centre
Authors: Gallen Rory A , O’Mahony James F , M Kuntz Karen , McGorrian Catherine , Casserly Ivan P , J Blake Gavin 
Published: February 2025

BackgroundPercutaneous coronary intervention (PCI) is a well-established treatment for coronary artery disease, one of the most significant causes of morbidity and mortality worldwide. Intracoronary imaging, including intravascular ultrasound (IVUS) and optical coherence tomography (OCT), has been shown to improve outcomes for patients following PCI by reducing complications and the need for repeat procedures. Uptake remains highly variable, in part due to concerns over up-front costs.AimThe purpose of this micro-costing analysis was to establish the costs and resource implications of PCI with and without intracoronary imaging.MethodsThe costing model considered costs associated with the index procedure and related hospital admission and was designed using data obtained from primary data collection, previously published literature and expert opinion. Unit costs were established through communication with the hospital finance department and industry representatives and were reported in 2024 euro. Costs were categorised as staffing, capital and consumables. Staffing costs were calculated in accordance with local guidelines. Capital costs were averaged over a 10-year period. A sensitivity analysis was conducted to assess the impact of the use of IVUS and OCT during PCI.ResultsThe use of intracoronary imaging extends the average procedure time from 45 min to 60 min. The total procedural cost of PCI without intracoronary imaging was €3082. The incremental cost with intracoronary imaging was €752 for IVUS and €884 with OCT.ConclusionThis study provides robust data on the cost drivers of PCI with intracoronary imaging in Ireland which has not previously been described. This framework may be of use to finance departments and physicians alike when seeking to establish the cost and resource implications of future modifications to PCI procedures, such as the description of the impact of intracoronary imaging in this study.
Cost-effectiveness of a community first responder system for out-of-hospital cardiac arrest in Belgium
Authors: de Greef Bianca , Genbrugge Cornelia , Verma Sanjay , Medic Goran , Maurer Joachim , Kooy Tom A , Hoogmartens Olivier , Sabbe Marc 
Published: February 2025

ObjectiveOut-of-hospital cardiac arrest (OHCA) is a major public health challenge across Europe, with a survival rate of only 8.5% to hospital discharge. Implementing a community first responder (CFR) system, including earlier Basic Life Support and defibrillation, can enhance survival rates and neurological outcomes. This study assesses the cost-effectiveness of two scenarios for implementing such a system in Belgium.MethodsA decision tree and the long-term Markov model were used to evaluate cost-effectiveness by comparing two scenarios with current care standards. Scenario 1 involved an awareness campaign on OHCA, while Scenario 2 included implementing a CFR system with automated external defibrillator (AED) integration, dispatch centre linkage and training for citizen responders. The analysis covered survival to the emergency department, hospital, discharge and neurologically intact survival, with sensitivity analyses to test robustness.ResultsThe awareness campaign and implementation of the CFR system resulted in an incremental cost-effectiveness ratio of €14,976 and €16,442 per quality-adjusted life year gained for scenarios 1 and 2, respectively. Both scenarios showed improvements in survival rates at various stages, including hospital discharge and neurologically intact survival.ConclusionThis study highlights the benefits of enhancing Belgium’s CFR for OHCA patients. It suggests that accessible AEDs, trained CFRs and an integrated emergency response system could improve survival rates and quality of life. These findings can guide policy and resource decisions, potentially improving the effectiveness and cost-efficiency of OHCA emergency services. Additionally, this approach could serve as a model for other regions aiming to strengthen their response to time-sensitive emergencies.
Handoffs and transitions of care in the intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
Authors: Appelbaum Rachel D , Farrell Michael S , Hoth J Jason , Jung Hee Soo , Pathak Abhijit , Nassar Aussama K , Cuschieri Joseph , Stein Deborah M , Agapian John V 
Published: February 2025

ObjectivesThe American Association for the Surgery of Trauma (AAST) Critical Care Committee chose handoffs and transitions of care in the intensive care unit (ICU) as a clinically relevant topic for review. This clinical consensus document aims to provide practical guidance to the surgical intensivist on the best practices for patient handoffs and transitions of care.MethodsA working group was formed from the committee-at-large to complete this work. The members of the working group were each assigned a subtopic to review using research to date. The research on which the recommendations are based was compiled at the discretion of the working group. Any topic with discrepant or minimal supporting literature was reviewed by the AAST Critical Care Committee through an anonymous survey.ResultsRecommendations for healthcare handovers include formally recognized handoffs at dedicated times, an interactive verbal exchange including all patients with a focus on what to anticipate or what is needs to be completed, tools to record and maintain information, and training to new providers on the handoff process and technology.ConclusionAs clinicians, we strive to provide the best evidence-based care to our patients. It is essential to study these high states, ICU handoffs to enhance the safety, efficiency, and effectiveness of patient care transitions, ultimately leading to better patient outcomes and provider satisfaction.Level of evidenceV.
The precession of particle spin in spherical symmetric spacetimes
Authors: Pang Xiankai , Jiang Qingquan , Xiang Yunchuan , Deng Gao-Ming 
Published: February 2025

Abstract
In this work, we will explore the precession of particle spins in spherical spacetimes. We first argue that the geometrical optics (WKB) approximation is insufficient, due to the absence of a glory spot in the backward scattering of massless particles, making an analysis of spin precession necessary. We then derive the precession equation assuming the spin is parallel transported, which is supported by the sub-leading order of the WKB approximation. The precession equation applies to both massless and massive particles. For particles moving at the speed of light, we show that spin is always reversed after backward scattering in any spherically symmetric spacetime, confirming the absence of a glory spot for massless particles. Finally, we solve the precession equation for Schwarzschild and Reissner–Nordström spacetimes and discuss the spin precession of massive particles, particularly in the non-relativistic limit. We find that, in Schwarzschild spacetime, the spin precession for particles moving with very small velocities compared to the speed of light depends only on the deflection angle, while in Reissner–Nordström spacetime, it also depends on the black hole charge, as revealed by the expansion derived from the strong lensing approximation.