bluuebunny/crossref_metadata_2025_split huggingface dataset:
Encapsulation and retention of 225Ac, 223Ra, 227Th, and decay daughters in zircon-type gadolinium vanadate nanoparticles
Authors: Toro-González Miguel , Dame Ashley N. , Mirzadeh Saed , Rojas Jessika V. 
Published: September 2020

Abstract
Unwanted targeting of healthy organs caused by the relocation of radionuclides from the target site has been one of the limiting factors in the widespread application of targeted alpha therapy in patient regimens. GdVO4 nanoparticles (NPs) were developed as platforms to encapsulate α-emitting radionuclides 223Ra, 225Ac, and 227Th, and retain their decay daughters at the target site. Polycrystalline GdVO4 NPs with different morphologies and a zircon-type tetragonal crystal structure were obtained by precipitation of GdCl3 and Na3VO4 in aqueous media at room temperature. The ability of GdVO4 crystals to host multivalent ions was initially assessed using La, Cs, Bi, Ba, and Pb as surrogates of the radionuclides under investigation. A decrease in Ba encapsulation was obtained after increasing the concentration of surrogate ions, whereas the encapsulation of La cations in GdVO4 NPs was quantitative (∼100%). Retention of radionuclides was assessed in vitro by dialyzing the radioactive GdVO4 NPs against deionized water. While 227Th was quantitatively encapsulated (100%), a partial encapsulation of 223Ra (∼75%) and 225Ac (>60%) was observed in GdVO4 NPs. The maximum leakage of 221Fr (1st decay daughter of 225Ac) was 55.4 ± 3.6%, whereas for 223Ra (1st decay daughter of 227Th) the maximum leakage was 73.0 ± 4.0%. These results show the potential of GdVO4 NPs as platforms of α-emitting radionuclides for their application in targeted alpha therapy.
Sémiotique textuelle et albums pour la jeunesse: intertextualité et lecteur modèle
Authors: Guillemette Lucie 
Published: September 2020

Résumé
Selon la perspective de l’œuvre ouverte développée par Eco, « un texte est un tissu d’espaces blancs, d’interstices à remplir … un mécanisme paresseux qui vit sur la plus-value de sens qui y est introduite par le destinataire » (Eco 1985, Lector in fabula ou la coopération interprétative dans les textes narratifs, Myriem Bouzaher (trad.). Paris: Grasset, 66–67). C’est à cette plus-value de sens, concomitante à l’activité interprétative, que la présente étude s’attardera, et ce, afin d’identifier d’abord des éléments de l’album d’enfance nécessitant l’interprétation d’un lecteur modèle et d’en convoquer par la suite les significations qui peuvent être appliquées au texte.
Plus précisément, il s’agira de décrire et d’analyser les mécanismes intertextuels qui enrichissent l’organisation syntaxique et sémantique de quatre albums d’enfance parus au Québec entre 1992 et 2002 et qui nécessitent l’intervention d’un lecteur modèle pour identifier les systèmes de signification et les savoirs qui y sont rattachés. Les albums soumis à l’investigation reprennent le schéma narratif de contes de fée connus et celui d’une nouvelle contemporaine. L’hypothèse est la suivante: si les composantes génériques de l’album dévoilent à un jeune lecteur des univers de références connus et familiers, le processus de l’intertextualité sollicite des contenus qui, soumis à l’interprétation d’un lecteur modèle, font parfois surgir des structures de signification inattendues.
Theoretical and experimental solid state studies of Ethyl 1-benzyl-2-(thiophen-3-yl)-1H-benzo[d]imidazole-5-carboxylate
Authors: Madan Kumar Shankar , Kumar Vasantha , Al-Ghorbani Mohammed , Shivaram Holla Bantwala , Poojary Boja , Praveen Padikkaruvanth , Chandra Nayak Siddaiah , Mohan Janani S. , Thamotharan Subbiah , Shamprasad Varija Raghu , Lokanath Neratur Krishnappagowda , Al-Zaqri Nabil , Alsalme Ali 
Published: September 2020

Abstract
The title compound Ethyl 1-benzyl-2-(thiophen-3-yl)-1H-benzo[d]imidazole-5-carboxylate (BI) is prepared and characterized using spectroscopic methods. The theoretical optimization and three dimensional molecular structure are confirmed by X-ray diffraction method (single crystal). The C–H…π intermolecular interactions stabilize the crystal structure. The intermolecular contacts in the crystal structure are quantified using Hirshfeld surfaces and the crystal packing is elucidated using 3D energy frameworks analysis. In the frameworks, the dispersion energy term is dominated over the electrostatic energy term. The structural optimization was carried out with B3LYP/6-311++G (d, p) level of theory. The visual representations of positive and negative potentials (electrostatic potential) are mapped on the electron density isosurface. The band gap energy (HOMO-LUMO) of the molecule is calculated to be 4.36 eV. Structural conformation of BI is compared with similar structures.
El árabe ya¯ ( یا ) y su uso en castellano medieval
Authors: Álvarez Blanco Aquilino 
Published: September 2020

En este trabajo no solamente se describen y analizan los rasgos relativos a la morfología, las funciones y los usos de la marca de vocativo e interjección árabe ya¯ ( یا ), sino también su presencia en romance bajo la forma ya en diferentes textos, como las jarchas1, los zéjeles y el Cantar de Mio Cid. Un segundo objetivo es cotejar las ediciones en busca de la mejor traducción, ya que, cuando se utiliza en algunas modernizadas, su equivalencia con ¡oh! no siempre es posible ni acertada.
https://doi.org/10.17398/2660-7301.42.5
Disturbances of carbohydrate metabolism and postoperative complications after distal pancreatic resection
Authors: Barykov V. N. , Istomin A. G. , Markina N. V. , Tyulganova V. L. 
Published: September 2020

Objective. To study the state of carbohydrate metabolism in patients after distal pancreatic resection and its effect on the development of postoperative complications.
Materials and methods. Over 10 years, 47 patients have been operated on with various tumors of the body/tail of the pancreas and complications of chronic pancreatitis. In 16 of them, concomitant diabetes mellitus was diagnosed before surgery, and in 31 patients, carbohydrate metabolism was normal.
Results. After surgery, from a group of patients with unchanged carbohydrate metabolism, 8 (25.8 %) developed diabetes mellitus. The following postoperative complications pancreatic fistula, inflammatory infiltrates and "fluid leakages in the abdominal cavity occurred in 68 % of cases. Out of 24 patients with diabetes mellitus, complications were registered in 21 (87.5 %) and of 23 diabetes-free patients in 11 (47.8 %).
Conclusions. The total risk for the development of the postoperative abdominal complications after the distal resection in patients with diabetes mellitus, diagnosed before and after the intervention, is 7.6 times higher than in patients without diabetes.
Enterolithiasis
Authors: Davidov M. I. , Nikonova O. E. 
Published: September 2020

Objective. To study the prevalence, etiopathogenesis, clinical features, diagnosis and treatment of enterolithiasis.
Materials and methods. For 26 years, 30 patients (16 men, 14 women) with intestinal calculi were observed. Elderly and senile patients prevailed (18 persons). Six patients had enterolites, 24 coprolites. In general, 41 calculi measuring from 2.5 to 22 cm (31 concrement was 6 cm and larger) were diagnosed in patients. Calculi were most often formed in the sigmoid and rectum. Fibrocolonoscopy, proctosigmoidoscopy, ultrasound, computed tomography were used.
Results. It was established that chronic colonic stasis, congenital and acquired intestinal diseases, intake of indigestible and extraneous for the intestine substances (chalk, barium, magnesium and aluminum salts) played a leading role in the formation of intestinal calculi. In 25 patients, calculi caused complications, of which the most severe were perforation of the intestine and acute intestinal obstruction.
Conclusions. Improvement of diagnostics and the developed differentiated treatment tactics permitted to improve treatment results better and achieve recovery in all 30 patients.
Thoracoscopy and chemical pleurodesis in treatment of pancreatogenic pleural effusion
Authors: Plaksin S. A. , Kotelnikova L. P. , Farshatova L. I. 
Published: September 2020

Objective. To determine the opportunities of thoracoscopy and the effectiveness of induction of chemical pleurodesis by intrapleural administration of drugs for pancreatogenic pleurisy.
Material and methods. We analyzed the results of surgical treatment of 17 patients with acute pancreatitis and 14 with pancreatic cysts after necrosis complicated by pancreatogenic pleural effusions, accounting for 3,7 % of all effusions.
Results. Mild and moderate pleurisy was successfully suppressed in 4 cases (12.9 %) by pleural punctures. Six patients (19.4 %) with pancreatic necrosis and huge pleural effusion in case of severe conditions underwent pleural drainage. In 20 cases (64.5 %), fragmented pleurisy was treated using thoracoscopy. Pleurodesis was performed by means of insufflation of talcum powder in five cases that permitted to reduce the drainage time from 7.14 2.96 days without pleurodesis to 4.2 1.1 days (p = 0.026). Pleurodesis using application of trichloroacetic acid had no effect in three patients. Five patients received 200300 g of octreotide diluted with 40 ml of isotonic sodium chloride solution into the pleural cavity through the drainage. The drainage period reduced to 3.5 1.0 days (p = 0.018). The effect was maximally expressed in the cases with high amylase level in the pleural exudate. After that, 20 patients underwent various operations on the pancreas.
Conclusions. Thoracoscopy is indicated to patients with pancreatogenic pleurisy for removal of fragments and sanation of the pleural cavity. Intraoperative pleurodesis with talcum effectively suppresses pleurisy and reduces the drainage period while application of trichloroacetic acid has no essential influence. Intrapleural administration of octreotide allows rapid reducing exudation when amylase index is high. Our study supports the effectiveness of mini-invasive procedures (videothoracoscopy combined with talcum powder pleurodesis and intrapleural administration of octreotide) to sanitize the pleural cavity, suppress pleurisy and shorten drainage periods.
Review: penyakit virus corona baru 2019 (COVID-19)
Authors: Hairunisa Nany , Amalia Husnun 
Published: September 2020

Sebuah virus corona baru diidentifikasi sebagai SARS-CoV-2, pertama kali teridentifikasi di Wuhan, Cina, pada Desember 2019 dan dikenal dengan nama COVID-19. Memiliki 85% homologi dengan SARS-CoV, S-protein pada virus ini akan mengikat reseptor target (ACE2) pada manusia terutama pada paru, jantung, dan ginjal. COVID-19 memiliki masa inkubasi lebih lama dan penularannya lebih tinggi. Penularan terjadi melalui droplet saluran nafas dan kontak erat dengan penderita. Pandemi terjadi dengan sangat cepat, hingga 19 Mei 2020 telah teridentifikasi 4.943.077 kasus dengan angka kematian 321.998 orang dari 212 negara. Gejala yang paling sering muncul adalah demam, fatique, batuk kering, myalgia, dan sesak. Tingkat keparahan penyakit meningkat pada lansia dan penderita dengan komorbid (penyakit jantung, diabetes melitus, penyakit paru kronis, hipertensi, dan kanker). Infeksi ini memiliki CFR sebesar 2.3% dan komplikasi yang paling sering menyebabkan kematian adalah komplikasi pada jantung dan paru. Hingga saat ini belum ditemukan pengobatan yang tepat maupun vaksin untuk penyakit ini, namun penelitian guna pengembangan pengobatan dan vaksin terus dilakukan di seluruh dunia. Upaya maksimal harus dilakukan karena wabah ini mempengaruhi infrastruktur kesehatan publik, ekonomi, dan seluruh aspek di semua negara di dunia. Tindakan pencegahan adalah sangat penting sebagai upaya memutus mata rantai penularan COVID-19.
Control scheme of thermal insulating door based on area linkage control structure
Authors: Yan Yujie , LV Bo , Yan Chao , Jiang Jiaoling , Xin Ke , Xiu Shengnan , Huang Chuwu , Wu Qu 
Published: September 2020

Taking the thermal insulating door as an example in which door blocks are driven by electric push rod, the area linkage control structure of block-groups has been established based on door blocks area linkage division. And multi-block control under different working conditions is realized. By employing PI controller to regulate single block to open and close, system controllability has been improved and control energy consumption has been reduced. The simulation results show that the proposed control scheme can relieve the heavy dependence of thermal insulating door control on manual operation to some extent.
La casa de todos
Authors: Krajnik Baquerizo Franz 
Published: September 2020

La llegada de la covid-19, junto a las medidas de cuarentena, nos permitió recordar que, solo en Lima, existen más de 3,000 personas que viven en las calles, sin que nadie asuma el desafío de ayudarlos.
En este contexto, la señorial Plaza de Toros de Acho se trasformó en Casa de Todos, un proyecto impulsado por la Municipalidad y la Beneficencia de Lima, que tiene por objetivo dar refugio a aquellas personas que se encuentran sin hogar en medio de la pandemia.
Penafsiran Kontemporer di Indonesia
Authors: Muhammad Asnajib  
Published: September 2020

The openness of thought in the world of contemporary interpretations at this time, making various groups competing to formulate a new understanding in the interpretation of the Qur'an. Including Muhammadiyah through the Tarjih Council and it's Tajdid formulating At-Tanwir's interpretation to add to the scientific treasury and answer contemporary problems through the approach of the original source of Islam, the Al-Qur'an. The purpose of this study is to analyze contemporary interpretations in Indonesia through the Study of the Interpretation Tafsir At -Tanwir written by K.H. Ahmad Dahlan, a Nusantara scholar, founder of Muhammadiyah. The methodology used in writing this research article is qualitative with a literature study approach. The primary sources in this study are the book of Tafsir At -Tanwir and documentation regarding the biography of K.H. Ahmad Dahlan. The analysis used is content analysis. The results of this study reveal that contemporary Penafisran as a foothold to respond to realities in life and growing problems. There is a paradigm shift from tafsir bil matsur, and bil Rayi to contemporary. Tasir At- Tanwir is one of Nusantara scholars' works in the Tafsir study, which is presented with the Maudui approach, which discusses contemporary issues. With characteristics: responsiveness, evoking dynamics and evoking ethos
Pengaruh disiplin kerja, budaya organisasi dan kepuasan kerja terhadap kinerja karyawan di PT. Muslimat Nusantara Utama Kabupaten Malang
Authors: Alfiyah Mahmudyahtin 
Published: September 2020

Penelitian bertujuan untuk mengetahui dan menganalisis pengaruh disiplin kerja, budaya organisasi, dan kepuasan kerja terhadap kinerja karyawan. Penelitian ini dilakukan di PT Muslimat Nusantara Utara Kabupaten Malang, dengan jumlah sampel sebanyak 35 karyawan. Pengumpulan data menggunakan kuesioner yang disusun dengan Skala Likert 5 poin. Teknik analisa yang digunakan adalah Regresi Linier Berganda. Hasil penelitian menunjukkan bahwa disiplin kerja, dan budaya organisasi berpengaruh signifikan terhadap kinerja karyawan, sedangkan kepuasan kerja tidak berpengaruh signifikan terhadap kinerja karyawan.
Pengaruh perceived value terhadap purchase intentions dimediasi customer satisfaction
Authors: Mukarromah Mukarromah 
Published: September 2020

Tujuan penelitian untuk mengetahui pengaruh langsung perceived value terhadap repurchase intention, serta untuk mengetahui pengaruh tidak langsung perceived value terhadap repurchase intention yang dimediasi kepuasan konsumen. Menggunakan sampel sebanyak 100 responden yang diambil dengan accidental sampling konsumen Naavagreen di Kota Malang. Teknik pengumpulan data menggunakan kuesioner yang disusun dengan Skala Likert 5 poin, dan telah memenuhi kriteria uji validitas dan reliabilitas instrumen. Teknik analisis data yang digunakan adalah Path Analysis. Hasil penelitian menunjukkan bahwa perceived value berpengaruh terhadap repurchase intention konsumen klinik kecantikan Naavagreen skincare, selain itu perceived value juga berpengaruh terhadap repurchase intention dimediasi oleh kepuasan konsumen klinik Naavagreen natural skincare cabang Malang
Pengungkapan sustainability report dan pengaruhnya terhadap kinerja perusahaan
Authors: Suaidah Yuniep Mujiati 
Published: September 2020

Penelitian ini bertujuan untuk mengetahui dampak pengungkapan sustainability report terhadap kinerja keuangan. Penelitian ini merupakan penelitian kuantitatif, metode pengumpulan data menggunakan dokumentasi sedangkan teknik analisis yang digunakan adalah MANOVA. Objek penelitian difokuskan pada perusahaan sektor tambang yang terdaftar di BEI tahun 2012-2016 dengan 20 sampel penelitian yang diperoleh menggunakan purposive sampling. Terkait dengan sustainability report indikator mengacu pada GRI-3 untuk tahun 2012 dan GRI-4 untuk tahun 2013-2016. Sedangkan untuk kinerja keuangan diukur menggunakan Return On Asset (ROA), Current Ratio (CR), dan Debt to Equity Ratio (DER). Hasil dari penelitian dapat diketahui bahwa sustainability report berpengaruh signifikan terhadap kinerja keuangan yang diukur dengan Return On Asset (ROA), sementara tidak berpengaruh signifikan terhadap Current Ratio (CR) dan Debt to Equity Ratio (DER).
CFTR improves myocardial ischemic/reperfusion injury through activating FUNDC1-mediated mitophagy and regulating ATP and mitochondrial functions
Authors: Zhang Yaping , Ding Nan , Yi Hanlu , Zhao Yudong , Yan Daole , Shen Lei , Li Zhiqiang , Zhu Yaobin 
Published: September 2020

Abstract
The authors have requested that this preprint be withdrawn due to erroneous posting.
In Utero and Peripubertal Metals Exposure in Relation to Reproductive Hormones and Sexual Maturation and Progression among Boys in Mexico City
Authors: Ashrap Pahriya , Meeker John D. , Sánchez Brisa N. , Basu Niladri , Tamayo-Ortiz Marcela , Solano-González Maritsa ,   Adriana Mercado-García4, Téllez-Rojo Martha M. , Peterson Karen E. , Watkins Deborah 
Published: September 2020

Abstract

Background: Endocrine disrupting chemicals (EDCs) such as metals have been reported to alter circulating reproductive hormone concentrations and pubertal development in animals. However, the relationship has rarely been investigated among humans, with the exception of heavy metals, such as Pb and Cd. Our aim was to investigate measures of in utero and peripubertal metal exposure in relation to reproductive hormone levels and sexual maturation and progression among boys from the Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) cohorts.Methods: Our analysis included 118 pregnant women and their male children from the ELEMENT study. Essential and non-essential metals were measured in urine collected from the mothers during the third trimester of pregnancy and their male children at 8-14 years. Reproductive hormone levels [serum testosterone, estradiol, dehydroepiandrosterone sulfate (DHEA-S), inhibin B, and sex hormone-binding globulin (SHBG)] were measured in blood samples from the children at 8-14 years. We also assessed Tanner stages for sexual maturation (genital, pubic hair development, and testicular volume), at two time points (8–14, 10-18 years). We used linear regression to independently examine urinary metal levels in relation to each peripubertal reproductive hormones adjusting for child age and BMI. Generalized estimation equations (GEEs) were used to evaluate the association of in utero and peripubertal metal exposures with sexual maturation and progression during follow-up based on Tanner staging and testicular volume.Results: In utero and prepubertal concentrations of some urinary metals were associated with increased levels of peripubertal reproductive hormones, especially non-essential metal(loid)s As and Cd (in utero), and Ba (peripubertal) as well as essential metal Mo (in utero) in association with testosterone. More advanced pubic hair developmental stage and higher testicular volume at the early teen visit was observed for boys with higher non-essential metal concentrations, including in utero Al and peripubertal Ba, and essential metal Zn concentration (peripubertal). These metals were also associated with slower pubertal progression between the two visits.Conclusion: These findings suggest that male reproductive development may be associated with both essential and non-essential metal exposure during in utero and peripubertal windows.
Size and temperature effects on dielectric breakdown of ferroelectric film capacitors
Authors: Tong Sheng 
Published: September 2020

Abstract
The paper introduces a model of dielectric breakdown strength. The model integrated thermal breakdown and defect models, representing the relationship between the electric field of ferroelectric films and dimensional parameters and operating temperature. This model is verified with experimental results of the lead lanthanum zirconate titanate (PLZT) films of various film thickness ( d = 0.8 – 3 m m), electrode area ( A = 0.0020 – 25 mm 2 ) tested under a range of operating temperature ( T = 300 – 400 K) with satisfying fitting results. Also learned is a relationship that the recoverable electric energy density is directly proportional to the square of breakdown electric field. This relationship is found viable in predicting the electric energy density in terms of variables of d , A , and T for the PLZT films.
Uterine inversions of tumor origin in two cases at the Joliot Curie Institute at the Aristide Le Dantec University Hospital Center
Authors: KA SIDY , DIAKHATÉ ABDOULAYE , DIOP DABA , SOME ROLAND OLLO , DIALLO ADJA COUMBA , BAH MALICK , DEM AHMADOU 
Published: September 2020

Abstract
Introductionnon-puerperal uterine inversions are a rare situation. Indeed, 85% of uterine inversions are puerperal. We report 2 cases observed at the Joliot Curie Institute of the Aristide Le Dantec University Hospital.Case PresentationIt was about a 39-year-old primigravida and a 47-year-old seventh gestational patient, who had a stage 4 of uterine inversion picture in relation to uterine sarcoma and uterine myoma respectively. The diagnosis was suspected at the clinic due to the absence of palpation of the uterus. Confirmation was made on medical imaging and intraoperatively. Management was radical with a total hysterectomy with bilateral adnexectomy via the vaginal and abdominal routes. However, in the first patient with sarcoma, surgery combined bilateral pelvic lymphadenectomy and was preceded by chemotherapy.Conclusionnon-puerperal uterine inversion is a rare situation. Its treatment is essentially surgical. However, it is important to look for an etiology and in the case of a tumor to ensure that the mass is a cancer or not because the management and prognosis depend on it.