bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiovascular Disease and COVID-19: What’s the Issue?
Authors: Bayushi Eka Putra  , Anwar Santoso  
Published: November 2020

What’s our status?
As per 17 April 2020, Indonesia has the most confirmed cases (5.923 cases) of Coronavirus Disease (COVID-19) among Southeast Asian Countries.1 Considering the daily increase of cases, we are considered nowhere near the plateau of the epidemic curve. It was predicted that the peak may be reached from May to June.2 Predictably, this will not end soon.
COVID-19 contracted patients may also vary in severity. The patient may present with no symptoms, mild to moderate, and severe condition. Mild (81%) depicted as COVID-19 patients with no evidence or mild pneumonia, severe (14%) for COVID-19 patients with hypoxia and >50% lung involvement within 24-48 hours, critical (5%) if the patient develops shock, acute respiratory distress syndrome, myocarditis, or even organ failure which need intensive care, and 2.3 % were fatal which end up in death.3,4
Relationship between Age and Activities of Daily Living using Modified Shah Barthel Index on Stroke Patient in Chronic Phase
Authors: Yunifananda Malika Sabrina , Kusumaningsih Widjajalaksmi 
Published: November 2020

Background: Stroke is the chief cause of long-term disability in the world. Predominantly, the disease is known as a degenerative disease on geriatrics age group, yet several studies have proven that incidence on productive ages are also increasing.
Objective: The study aimed to know whether there are any difference in Modified Shah Barthel Index (MSBI) score in different age group, geriatric and productive age group and to know independence score in daily activities based on age.
Method: The study utilized the cross-sectional design and analytical observational method. Twenty five samples of chronic stroke patients was recruited and grouped into two groups productive and geriatric age group. MSBI score was calculated and compared between two groups.
Result: Bivariate analysis proves that there is a significant association between MSBI score and age of stroke patients on chronic phase (p=0.017).
Discussion. There is a significant association between age and MSBI score on stroke patients in chronic phase.
Conclusion: There was a significance difference between productive and geriatric age with daily activities using MSBI in chronic stroke patients. The productive age group has a higher Modified Shah Barthel Index score than the geriatric age group.
New Testament Christology: A Critique of Hurtado’s Influence
Authors: Kugler Chris 
Published: November 2020

Abstract
This article offers a critique of one of the most crucial and controversial pillars of Larry W. Hurtado’s reconstruction of the origins and nature of earliest “Jesus ­devotion.” Unlike most other engagements with Hurtado, this article takes seriously into account all of his published work and not simply his magnum opus, Lord Jesus Christ. Likewise, unlike most other engagements, this article critically focuses on the explanatory relationship between Hurtado’s minimalist account of the Christology of Jesus and his earliest disciples and the postulation that powerful Easter and post-Easter “religious experiences” played the key role in the origins of Jesus devotion. Essentially, this article contends that Hurtado’s persuasive case concerning the very early origins of Jesus devotion (perhaps, so he argues, to be dated as early as the first few months of the post-Easter period) ought to have pushed his search for the major causes of such devotion back beyond the “religious experiences” of post-Easter Christians and into the life of the historical Jesus himself.
Truth, Truths, and Pluralism
Authors: Stuhr John J. 
Published: November 2020

ABSTRACT
I document the contemporary war on truth by authoritarian leaders and regimes, focusing on its distinctive sites, scope, and tactics. In this context, I explain both the pressing need to defend pluralism and the ways pluralism has been co-opted for antidemocratic goals. This defense of pluralism includes an epistemic creed and, flowing from this creed, four strategies for action to counter the war on truth: change of government leadership through the electoral process (and the resources this involves and the institutions this assumes); countertactics to the new authoritarian communication techniques (and all the vigilance and energy this involves); creation of individual habits enabled by the skills of effective inquiry, communication, and imagination (through educational processes that include but are not limited to the schools); and, adequate resources, freedom, and public commitment to institutions that produce truth and accept different truths—research and education, the press and media, and the courts and judicial system. I claim that collectively these four responses are the only possibly effective ones—and thus that they all are necessary. Whether or not they are sufficient is an issue that rests with melioristic action and, thus, can be judged only after and by the consequences of that action.
Can Facts Survive? Lies and the Complicity of Common Sense
Authors: Flakne April 
Published: November 2020

ABSTRACT
Can “facts” survive the advent of modern political practices of lying? This essay revisits Arendt's “Truth and Politics” to explore this question. Arendt ties the fate of facts closely to that of common sense, which both depends upon facts and is charged with combating the lies that would assault not only individual facts but factuality itself. Arendt hewed closely to our two major philosophical traditions of common sense. While she recognized the ways in which common sense as koine aisthesis, or an individual faculty of epistemological coherence, could be co-opted by totalitarian ideology, she was less aware of how her own notion of “community sense” (following the tradition of sensus communis) could be pressed into the service of an accelerating democratic/capitalist conversion of facts into opinions (“opinionization”). Given the co-optation of these traditions of common sense by modern practices of political lying, I argue for an alternative approach, inspired by Aristotle and rooted in perception, where “sensing in common” nurtures a sense of [what can come to be held in] common.
Taxonomic Studies on Australian Psammoecus Latreille (Coleoptera, Silvanidae, Brontinae)
Authors: Karner Michael 
Published: November 2020

Two new species of Psammoecus Latreille, 1829 from Australia are described: Psammoecus australis sp. nov. and P. venustus sp. nov. A taxonomic revision and diagnoses for other Australian species are provided. Psammoecus obesus Grouvelle, 1919 is recorded from Australia for the first time. Two new synonyms are discovered: Psammoecus t-notatus Blackburn, 1908 = P. amoenus Grouvelle, 1912 syn. nov.; Psammoecus vittifer Blackburn, 1903 = P. concolor Grouvelle, 1919 syn. nov. A lectotype is designated for Psammoecus concolor Grouvelle, 1919.
Targeting immunogenic cell death in cancer
Authors: Ahmed Asma , Tait Stephen W.G. 
Published: November 2020

Immunogenic cell death (ICD) is a type of cancer cell death triggered by certain chemotherapeutic drugs, oncolytic viruses, physicochemical therapies, photodynamic therapy, and radiotherapy. It involves the activation of the immune system against cancer in immunocompetent hosts. ICD comprises the release of damage‐associated molecular patterns (DAMPs) from dying tumor cells that result in the activation of tumor‐specific immune responses, thus eliciting long‐term efficacy of anticancer drugs by combining direct cancer cell killing and antitumor immunity. Remarkably, subcutaneous injection of dying tumor cells undergoing ICD has been shown to provoke anticancer vaccine effects in vivo. DAMPs include the cell surface exposure of calreticulin (CRT) and heat‐shock proteins (HSP70 and HSP90), extracellular release of adenosine triphosphate (ATP), high‐mobility group box‐1 (HMGB1), type I IFNs and members of the IL‐1 cytokine family. In this review, we discuss the cell death modalities connected to ICD, the DAMPs exposed during ICD, and the mechanism by which they activate the immune system. Finally, we discuss the therapeutic potential and challenges of harnessing ICD in cancer immunotherapy.
Delivery of a mitochondria‐targeted antioxidant from biocompatible, polymeric nanofibrous scaffolds
Authors: Hamedani Yasaman , Teixeira Rayane Brinck , Karbasiafshar Catherine , Wipf Peter , Bhowmick Sankha , Abid M. Ruhul 
Published: November 2020

Cardiovascular disease has been associated with increased levels of reactive oxygen species (ROS). Recently, we have shown that a critical balance between cytosolic ROS and mitochondrial ROS is crucial in cardiovascular health and that modulation of mitochondrial ROS helps prevent detrimental effects of cytosolic ROS on endothelial cells (EC) in transgenic animals. Here, we report the development of a controlled delivery system for a mitochondria‐targeted antioxidant, JP4‐039, from an electrospun scaffold made of FDA‐approved biocompatible polymeric nanofibers. We demonstrate that the active antioxidant moiety was preserved in released JP4‐039 for over 72 h using electron paramagnetic resonance. We also show that both the initial burst release of the drug within the first 20 min and the ensuing slow and sustained release that occurred over the next 24 h improved tube formation in human coronary artery ECs (HCAEC) in vitro. Taken together, these findings suggest that electrospinning methods can be used to upload mitochondrial antioxidant (JP4‐039) onto a biocompatible nanofibrous PLGA scaffold, and the uploaded drug (JP4‐039) retains nitroxide antioxidant properties upon release from the scaffold, which in turn can reduce mitochondrial ROS and improve EC function in vitro.
Squaraine Dyes for Photovoltaic and Biomedical Applications
Authors: He Jin , Jo Young Jin , Sun Xianglang , Qiao Weiguo , Ok Jehyung , Kim Tae‐il , Li Zhong'an 
Published: November 2020

AbstractSquaraine dyes (SQs) are an important class of polymethine dyes with a unique reasonable‐stabilized zwitterionic structure, in which electrons are highly delocalized over the conjugated bridge. These dyes can not only be easily synthesized via a condensation, but also exhibit intense absorption and emission in the visible and near‐infrared region with excellent photochemical stability, making them attractive material candidates for many photoelectric and biomedical applications. Thus, in this review, after an introduction of SQs, the recent advances of SQs in the photovoltaic field are comprehensively summarized including dye‐sensitized solar cells, organic solar cells, and perovskite solar cells. Then, the important advances in the use of SQs as the biosensors, biological imaging, and photodynamic/photothermal therapy reagents in the biomedical field are also discussed. Finally, a summary and outlook will be provided with some new perspectives for the future design of SQs.
Surface Engineering in Mesoporous Single Crystal to Enhance Pseudocapacitance
Authors: Ye Lingting , Xi Shaobo , Li Hao , Lin Guoming , Xie Kui 
Published: November 2020

AbstractMesoporous single crystals combining the ordering of crystal lattice and the disordering of interconnected pores would create well‐defined structures confined at continuously twisted surfaces that are kinetically trapped. Here, mesoporous WN single crystal at 2 cm scale is grown to create and engineer the well‐defined surface structures. The unsaturated coordination structures including W–N1/2, W–N1/3, and W–N1/6 confined at twisted surfaces account for the chemisorption of H in acidic electrolyte and deliver a record high areal capacitance of ≈250 F cm−2 without degradation being observed even after 15 000 cycles. The engineering of well‐defined coordination structures at twisted surfaces would open an alternative to create active surfaces in the wealth of other single‐crystalline materials.
A Superhydrophobic Droplet‐Based Magnetoelectric Hybrid System to Generate Electricity and Collect Water Simultaneously
Authors: Ma Zheng , Ai Jingwei , Shi Yunsong , Wang Kun , Su Bin 
Published: November 2020

AbstractTraditional electromagnetic generators used in hydraulic power generation are heavy, bulky, and immovable, and are thus unsuitable for low water supply. A portable miniature electromagnetic system that can harvest energy from rainwater is critical for developing a sustainable energy strategy. In this study, a superhydrophobic droplet‐based magnetoelectric hybrid system is fabricated, that can generate electricity from tiny water droplets. The magnetoelectric system (MS) comprises three parts: a superhydrophobic surface containing a conductive coil, liquid droplets, and a superhydrophobic magnetic powders/Ecoflex base. The mechanical impact of a falling water droplet onto the assembled system is transformed into electricity. Maxwell numerical simulation is used to analyze the related mechanism; the magnetoelectric performance is further improved by modifying the process parameters such as droplet falling velocity and magnetic powder contents. Furthermore, a model is developed, comprising the MS and a cactus‐like superhydrophobic patterned plate that can generate electricity and collect water from fog, simultaneously. The described magnetoelectric strategy is believed to enhance and extend functions in energy harvesting and provide a generalized method to exploit new systems toward sustainable energy development.
Near‐Field Communication Powered Hydrogel‐Based Smart Contact Lens
Authors: Vásquez Quintero Andrés , Arai Ritsuko , Yamazaki Yoshiko , Sato Takao , De Smet Herbert 
Published: November 2020

AbstractNowadays, smart contact lenses (SCLs) display interesting features for healthcare monitoring; however, their comfort and practical usability strongly depend on the outermost material in contact with the eye. In this publication, the embedding of a custom‐made and thermoformed Near‐Field Communication based circuit in a conventional soft CL is presented. The circuit is composed of gold tracks on polyimide between thermoplastic polyurethane layers (insert), while the lens is based on industry standard double‐molding process of poly(2‐hydroxyethyl methacrylate) with proven compatibility with corneal tissue. The lens shows stable geometrical parameters (bevel landing area) thus enabling a practical implementation. Finite element method models are used to optimize the thermoforming process in order to provide a stable and desired curvature of the insert before the embedding process. While the insert is designed to allow oxygen transmission at the center of the lens, a custom‐made ultra‐compact radio‐frequency antenna provides communication and wireless power transfer both in air and inside saline solutions. The successful combination of the intrinsic soft mechanical properties of the wirelessly powered electronic insert with conventional hydrogel materials and manufacturing processes delivers a practical solution for SCLs. This enables non‐invasive applications in fields such as vision correction and/or biomedical sensing.
VCAM‐1‐Targeted Gene Delivery Nanoparticles Localize to Inflamed Endothelial Cells and Atherosclerotic Plaques
Authors: Distasio Nicholas , Salmon Hugo , Dierick France , Ebrahimian Talin , Tabrizian Maryam , Lehoux Stephanie 
Published: November 2020

AbstractThe ability to target nanoparticles to the dysfunctional endothelium may present a new and innovative therapy for cardiovascular disease. In this work, an anti‐inflammatory gene therapy nanoparticle targeted to VCAM‐1, a protein overexpressed by inflamed endothelial cells located within atherosclerotic plaque, is developed. Targeting is accomplished via a peptide‐grafted coating for the nanoparticles. Nanoparticle binding to VCAM‐1 is probed via surface plasmon resonance with imaging to determine kinetics and binding dynamics. Targeted nanoparticles are internalized by transfected inflamed primary endothelial cells more than nontargeted controls (80% vs 30% positive cells) under both static and dynamic flow conditions. The nanoparticles also bind specifically to VCAM‐1+ endothelial cells within atherosclerotic plaque from mouse models in both the aortic sinus and whole aorta. Taken together, this nanoparticle formulation may be an effective and specific strategy for anti‐inflammatory therapy within the context of atherosclerosis.
Benefits, Problems, and Solutions of Silver Nanowire Transparent Conductive Electrodes in Indium Tin Oxide (ITO)‐Free Flexible Solar Cells
Authors: Azani Mohammad‐Reza , Hassanpour Azin , Torres Tomás 
Published: November 2020

AbstractIn this review, silver nanowires (AgNWs) are introduced, as the primary material to replace indium tin oxide for fabricating cost‐effective flexible organic solar cells (FOSCs), because of their remarkable solution‐processing, flexibility, transparency, and conductivity, along with their enhanced properties in terms of light‐scattering, plasmonic effects, and transmittance in the near infrared region. The drawbacks of AgNWs, particularly their high roughness, low adhesion to substrates, atmospheric corrosion, degradation under UV and visible light, and poor contact at wire‐wire junctions, must be resolved prior to their use in commercial FOSCs applications. Herein, comparisons among all candidates (e.g., graphene, carbon nanotubes, metal grids, and conducting polymers), along with a report of all recent progress in addressing these issues for using AgNWs as flexible transparent conductive electrodes (TCEs), are discussed. In addition, recent publications on the fabrication of highly efficient FOSCs based on AgNWs are summarized. The discussed issues regarding AgNWs‐TCEs apply not only to FOSCs, but can be generalized for other third‐generation solar cells, such as perovskite solar cells and dye‐sensitized solar cells; additionally, they provide insight for other optoelectronic applications, such as organic light‐emitting diodes, liquid crystal displays, smart windows, touch panels, and heaters.
Quantifying the impacts of waterlogging on cotton at different growth stages: A case study in Hubei Province, China
Authors: Qian Long , Chen Xiaohong , Gao Yawen , Deng Kenan , Wang Xiugui , Zeng Wenzhi , Luo Yunying 
Published: November 2020

AbstractWaterlogging severely restricts cotton (Gossypium hirsutum L.) production worldwide. To assess the impacts of waterlogging on cotton yield, a series of field experiments with multi‐form waterlogging were conducted during four cotton growth stages in Hubei Province, China from 2003 to 2011. Moreover, regional waterlogging events were characterized by the sum of excess rainstorm amount index (SER) and the sum of excess standardized precipitation and evapotranspiration index (SESPEI); accordingly, the spatiotemporal variations in waterlogging in Hubei Province during 1961–2019 were analyzed. The results showed that the 1980s was the most waterlogging‐prone decade and northeastern Hubei was the most waterlogging‐prone region for Hubei. The impact of surface waterlogging on cotton was greater than that of subsurface waterlogging, and the impact of their combined stress was lower than the additive effects of individual stresses. The most waterlogging‐sensitive cotton growth stage was the flowering and boll‐forming stage, whereas the most waterlogging‐proneness growth stage was the budding stage. A normalized waterlogging index integrating both waterlogging sensitivity and proneness indicated that the budding and the flowering and boll‐forming stages were the periods when cotton suffered the greatest waterlogging impacts. Both the SESPEI and SER were significantly (p < .05) and negatively related to the detrended cotton yield, and the former was found more efficient in describing the negative effects of waterlogging. In conclusion, different forms of waterlogging should be accounted for in‐field drainage schedules, and extra attention should be paid during the budding and the flowering and boll‐forming stages of cotton, especially for northeastern Hubei.
Copper‐Catalyzed and Proton‐Directed Selective Hydroxymethylation of Alkynes with CO2
Authors: Wang Mei‐Yan , Jin Xin , Wang Xiaofei , Xia Shumei , Wang Yue , Huang Shouying , Li Ying , He Liang‐Nian , Ma Xinbin 
Published: November 2020

AbstractAn intriguing strategy for copper‐catalyzed hydroxymethylation of alkynes with CO2 and hydrosilane was developed. Switched on/off a proton source, for example, tBuOH, direct hydroxymethylation and reductive hydroxymethylation could be triggered selectively, delivering a series of allylic alcohols and homobenzylic alcohols, respectively, with high levels of Z/E, regio‐ and enantioselectivity. Such a selective synthesis is attributed to the differences in response of vinylcopper intermediate to proton and CO2. The protonation of vinylcopper species is demonstrated to be prior to hydroxymethylation, thus allowing a diversion from direct alkyne hydroxymethylation to reductive hydroxymethylation in the presence of suitable proton.
Electro‐Descriptors for the Performance Prediction of Electro‐Organic Synthesis
Authors: Chen Yuxuan , Tian Bailin , Cheng Zheng , Li Xiaoshan , Huang Min , Sun Yuxia , Liu Shuai , Cheng Xu , Li Shuhua , Ding Mengning 
Published: November 2020

AbstractElectrochemical organic synthesis has attracted increasing attentions as a sustainable and versatile synthetic platform. Quantitative assessment of the electro‐organic reactions, including reaction thermodynamics, electro‐kinetics, and coupled chemical processes, can lead to effective analytical tool to guide their future design. Herein, we demonstrate that electrochemical parameters such as onset potential, Tafel slope, and effective voltage can be utilized as electro‐descriptors for the evaluation of reaction conditions and prediction of reactivities (yields). An “electro‐descriptor‐diagram” is generated, where reactive and non‐reactive conditions/substances show distinct boundary. Successful predictions of reaction outcomes have been demonstrated using electro‐descriptor diagram, or from machine learning algorithms with experimentally‐derived electro‐descriptors. This method represents a promising tool for data‐acquisition, reaction prediction, mechanistic investigation, and high‐throughput screening for general organic electro‐synthesis.
Wavelength‐Gated Adaptation of Hydrogel Properties via Photo‐Dynamic Multivalency in Associative Star Polymers
Authors: Ludwanowski Simon , Skarsetz Oliver , Creusen Guido , Hoenders Daniel , Straub Paula , Walther Andreas 
Published: November 2020

AbstractResponsive materials, such as switchable hydrogels, have been largely engineered for maximum changes between two states. In contrast, adaptive systems target distinct functional plateaus between these maxima. Here, we demonstrate how the photostationary state (PSS) of an E/Z‐arylazopyrazole photoswitch can be tuned by the incident wavelength across a wide color spectrum, and how this behavior can be exploited to engineer the photo‐dynamic mechanical properties of hydrogels based on multivalent photoswitchable interactions. We show that these hydrogels adapt to the wavelength‐dependent PSS and the number of arylazopyrazole units by programmable relationships. Hence, our material design enables the facile adjustment of the mechanical properties without laborious synthetic efforts. The concept goes beyond the classical switching from state A to B, and demonstrates pathways for a truly wavelength‐gated adaptation of hydrogel properties potentially useful to engineer cell fate or in soft robotics.