bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional polymorphism of the serotonin reuptake transporter SLC6A4 gene in various clinical variants of irritable bowel syndrome
Authors: Pushkina A. V. , Avalueva A. B. , Bakulin I. G. , Topanova A. A. , Murzina A. A. , Sitkin S. I. , Lapinsky I. V. , Skazyvaeva E. V. 
Published: December 2019

Rationale:Irritable bowel syndrome (IBS) is a multifactorial disease, the genetic aspect of which is being actively studied.Aim:To investigate functional polymorphism of the serotonin reuptake transporter (SERT)SLC6A4gene of various clinical variants of IBS.Materials and methods:We performed a cross-sectional single center study in 79 Caucasian patients with IBS (according to the Rome criteria IV). The patients were divided into two groups: group 1, IBS with diarrhea (IBS-D, n = 45) and group 2, IBS with constipation (IBS-C, n = 34). The control group included 59 Caucasian patients with gastrointestinal disorders without IBS. Polymorphism5-HTTLPRof theSLC6A4gene was assessed in all subjects. In group 1 patients, blood serotonin levels were measured and psychological tests were performed, including Spielberger's State / Trait Anxiety Inventory, quality of life by SF36 and GSRS, Asthenia scale, VAS scores for pain intensity.Results:Thirty-five of 45 (77.8%) patients with IBS-D carried the mutantSallele, which was significantly more frequent than in the IBS-C group (p = 0.002) and in the control group (p = 0.005). There were no statistically significant differences (p = 0.54) in the frequency of detection of the homozygousLLgenotype (normal allele) and the heteroand homozygous mutant alleles (SLandSS) genotype between the IBS-C and control patients. In the IBS-D group, a gender difference for the mutantSSallele of5-HTTLPRwas found, with significantly higher frequency in female patients (p = 0.0147). No significant gender differences in the genotype distribution between the patients with IBS-C and the control group were found. There were also no differences in blood serotonin levels in the IBS patients with various5-HTTLPRtypes (p = 0.086); they were all in the reference range. However, there was a trend towards lower serotonin levels in theLLgenotype carriers compared to those with theSS/SLpolymorphisms. The Gastroenterological inventoryGSRSdemonstrated significantly higher total score for the constipation syndrome in the patients with homozygousLL 5-HTTLPRpolymorphism, compared to that in the patients with theSS/SLgenotype (p = 0.013).Conclusion:The results may be related to lower expression of theSLC6A4gene in the carriers of the mutant allele in the5-HTTLPRpromoter and subsequent decreased rate of serotonin uptake, with resulting stimulation of the gastrointestinal tract. TheSERTpolymorphism of theSLC6A4gene is worth further investigation as a potential candidate gene in the IBS pathophysiology.
PERTIMBANGAN HAKIM DALAM PENJATUHAN PIDANA KEPADA ANAK YANG MELAKUKAN TINDAK PIDANA NARKOTIKA (Studi Putusan Pengadilan Negeri Stabat No. 10/Pid.Sus Anak/2015/PN.Stb)
Authors: Ratomi Achmad , Khairunnisa Khairunnisa 
Published: December 2019

<p>Penelitian bertujuan untuk menganalisis dasar hukum yang diterapkan oleh Majelis Hakim dan jenis pidana yang dijatuhkan oleh Majelis Hakim dalam Putusan Pengadilan Negeri Stabat No. 10/Pid.Sus Anak/2015/PN.Stb telah tepat. Dari penelitian tersebut diperoleh hasil di dalam dakwaan yang kedua Jaksa Penuntut Umum mendakwa dengan Pasal 114 ayat (2) UU Narkotika, sementara Majelis Hakim di dalam pertimbangannya menguraikan tentang unsur-unsur tindak pidana yang terdapat di dalam Pasal 112 ayat (1) UU Narkotika, yaitu dalam bentuk memiliki tanpa izin. Padahal di dalam amar putusannya Majelis Hakim menyatakan bahwa terdakwa terbukti secara sah dan meyakinkan menjadi perantara dalam jual beli. Dan terdapat ketidaksesuaian yaitu pada pertimbangnnya Majelis Hakim menilai bahwa pidana yang tepat untuk dijatuhkan adalah pidana pengawasan sebagaimana diatur di dalam Pasal 71 ayat (1) huruf b angka 3 dan Pasal 77 ayat (2) UU No. 11 Tahun 2012, sementara di dalam amar putusannya Majelis Hakim menjatuhkan pidana penjara dan denda. Penjatuhan pidana denda itu bertentangan dengan Pasal 71 ayat (3) UU No. 11 Tahun 2012.</p>Kata Kunci : Pertimbangan Hakim, Pidana Anak, Narkotika
Translation and Preliminary Validation of the Oncology Acuity Tool–French (for Switzerland)
Authors: DeCosterd Sandy , Brennan Caitlin W. , Bavaud Sylvie , Ballabeni Pierluigi , Eicher Manuela 
Published: December 2019

Background and PurposeFew tools exist to measure real-time patient demands for care and match them with the supply of available nurses. We translated the Oncology Acuity Tool into a French version (for Switzerland) and conducted preliminary validation.MethodsThe setting was two French-speaking Swiss hospitals. Methods included translation and harmonization by experts. Content validity was assessed among nine oncology nurses. Inter-rater reliability was evaluated based on case studies.ResultsContent validity results met or exceeded pre-set cut-points and inter-rater reliability results were moderate. Several indicators were changed, added or removed.ConclusionThe Swiss tool may improve real-time estimates of patients' nursing care needs and assist with efficient resource allocation. Additional validation studies are recommended.
Development and Psychometric Evaluation of the Elderly Hypertension Self-Care Index
Authors: Gholamnejad Hanieh , Kakhki Ali Darvishpoor , Ahmadi Fazlollah , Rohani Camelia 
Published: December 2019

PurposeThis study was done to develop and evaluate the psychometric properties of the Elderly Hypertension Self-Care Index.MethodsThis was an exploratory mixed method study. Items were developed through conducting a qualitative study with conventional content analysis approach and comprehensively reviewing the existing literature. Then, the developed index was assessed for face, content, and construct validity as well as reliability.ResultsAnalyses identified four themes of self-care: intelligent acceptance, self-actualization in the pass of the disease, effective supporters, and destructive constraints. Exploratory factor analysis revealed that only 28 items were appropriate which were loaded on six factors, accounting for 45.035% of the total variance of hypertension self-care. Cronbach's alpha and test–retest intraclass correlation coefficients of the index were 0.80 and 0.96, respectively.ConclusionThe Elderly Hypertension Self-Care Index showed that it is a valid and reliable index in the elderly health context; and can be used for self-care assessment among elderly people with hypertension.
The Minimal Eating Observation Form—Version II Revisited: Validity and Reliability
Authors: Westergren Albert 
Published: December 2019

Background and purposeThe Minimal Eating Observation Form—Version II (MEOF-II) is a screening and research tool for eating difficulties. Here we assess the psychometric properties of the tool.MethodsCross-sectional MEOF-II data, n = 5,956 persons (nursing home residents [n = 3,087]; in-hospital patients [n = 1,490]; mean age 76.9; 61% women). Data was analyzed taking account of the dichotomous nature of item-level data, that is, based on tetrachoric correlations.ResultsThe MEOF-II items (n = 9) belonged to one higher order unidimensional factor (61.7% explained variance, omega 0.92), and three lower level factors, with three items each (92.9% explained variance, omega 0.83–0.88): deglutition; ingestion; and energy/appetite.ConclusionThe study provides support for the reliability and validity of the MEOF-II total scale and subscales, and the findings are in line with previous studies.
Development and Psychometric Testing of the Maternal Nipple Shield Satisfaction Scale
Authors: Black Kathleen Darrah , Chertok Ilana Azulay , Acker Colette M. 
Published: December 2019

Background and PurposeNipple shield use is common among breastfeeding mothers, yet no instrument measures maternal satisfaction. The new Maternal Nipple Shield Satisfaction Scale (MNSSS) was evaluated for reliability and validity.MethodsThe MNSSS for was tested in two phases: women (N = 128) using nipple shields in the previous 6 months and the second, women, (N = 57) within the first 3 weeks postpartum.ResultsFrom the original 21-item scale, content validity analysis, Cronbach's alpha, item to total correlation testing, exploratory factor analysis resulted in a one factor scale consisting of nine items with a Cronbach's alpha of .90. Convergent validity testing resulted in a small, but significant negative correlation.ConclusionThe MNSSS may be a useful instrument for examining satisfaction of women using nipple shields for breastfeeding.
Measuring Fatigue in Older Adults With Joint Pain: Reliability and Validity Testing of the PROMIS Fatigue Short Forms
Authors: Hackney Alisha J. , Klinedinst N. Jennifer , Resnick Barbara 
Published: December 2019

Background and PurposeLimited literature exists regarding the psychometric properties of the Patient-Reported Outcome Measurement Information System (PROMIS) Fatigue Short Form 8a. This study compared the psychometric properties of the 8a to the established PROMIS Fatigue Short Form 7a.MethodsThis was a cross-sectional study of 31 older adults with joint pain. Equivalent forms reliability and a Rasch analysis explored reliability (equivalent forms, internal consistency), validity (unidimensionality, item INFIT/OUTFIT), and additional psychometrics (item mapping).ResultsThe measures were equivalent in measuring fatigue (r = 0.75, p < .001) with good internal consistency (α = .87−.92). Both were unidimensional. Even though the 8a had better fitting items, neither measure could differentiate low levels of fatigue.ConclusionThe 8a has comparable psychometric properties to the 7a in this population. Future work is needed in larger, more diverse samples.
A Population-Based Study on Association Between Cesarean Section and Neonatal Mortality in Nigeria
Authors: Olukade Tawa , Yaya Sanni , Bishwajit Ghose , Uthman Olalekan A. 
Published: December 2019

OBJECTIVETo examine the association between cesarean section and neonatal mortality Nigeria.METHODA retrospective analysis using Nigeria Demographic Health Survey 2013 national population-based cross-sectional survey. The national prevalence of cesarean section was calculated, and logistic regression was used to estimate the odds of neonatal mortality outcome following cesarean delivery.RESULTSThe national cesarean section rate for the 2009–2013 period was 2.1% among 31,495 deliveries. The odds of having a neonatal death was twice as high in cesarean deliveries in comparison to noncesarean deliveries (aOR = 2.56, 95% CI 1.75 to 3.74).CONCLUSIONCesarean section increases the odds of neonatal mortality in Nigeria. There is a need to scale up the quality and timeliness of emergency obstetric services offered to pregnant women.
The Woman-Centeredness of Various Dutch Maternity Service Providers During Antenatal and Postnatal Care
Authors: Fontein-Kuipers Yvonne , van Beeck Elise , Kammeraat Liesbeth , Rutten Fleur 
Published: December 2019

AIMSTo examine the woman-centeredness of maternity care providers from the woman's perspective. To investigate the validity and reliability of the Client Centered Care Questionnaire among a childbearing population.DESIGNA cross-sectional study.METHODSThe self-report Client Centered Care Questionnaire was administered to evaluate women's one-on-one antenatal and postnatal care appointments with various Dutch care providers: community and hospital-based midwives, General Practitioners, (registrar) obstetricians, sonographers, and maternity care nurses.RESULTSEight-hundred and fifteen completed questionnaires were received. Exploratory and confirmatory factor analyses provided support for a two-factor model, with an acceptable model fit. Woman-centeredness of all maternity care providers showed scores above baseline for the neutral value. Welch ANOVA showed a statistical significant effect of the type of maternity care practitioner in providing woman-centered care during antenatal and postnatal visits (F(5.8) = 7.79). The Bonferroni post hoc test showed that women assigned significantly higher woman-centered care scores to community-based midwives compared with hospital-based midwives (p .011) and compared with registrars/obstetricians (p < .001).CONCLUSIONAlthough overall scores of perceived woman-centeredness indicated a good to excellent performance of woman-centered care, with significantly higher scores for community-based midwives, it cannot be assumed that current woman-centered care completely meets the needs of Dutch childbearing women. The Client Centered Care Questionnaire (CCCQ) is an adequate instrument to measure woman-centered care in antenatal and postnatal maternity services. Further research regarding measuring woman-centered care is needed.
O VZŤAHU MEDZI POJMAMI VPLYV A INTERTEXTUALITA V TEÓRII A V INTERPRETÁCII
Authors: Šimakova Spevakova Marina 
Published: December 2019

V štúdii sa venujeme prehľadu vymedzených teoretických koncepcií, ktoré explikovali pojem vplyv vo vzťahu k pojmu intertextualita. V druhej časti štúdie analyzujeme podoby intertextuality v tvorbe Víťazoslava Hronca. Cieľom štúdie je na pozadí konkrétnych príkladov z literatúry vymedziť postoj k teoretickým východiskám.
ПОСЛОВНА КОМУНИКАЦИЈА И ПОЛИТИЧАРИ – НАСТУП У МЕДИЈИМА
Authors: Пралица Дејан 
Published: December 2019

Циљ овог рада јесте да покаже како политичари иступају у медијима. Седам издања телевизијске емисије Правi угао, на Првом програму Радио-телевизије Војводине, са осам гостију – политичара чини корпус истраживања о пословној комуникацији политичара приликом наступа у медијима. Параметри који се посматрају за оцену наступа су поштовање пословног бонтона (јасан и недвосмислен говор, персирање) и аспекти невербалне комуникације: говор тела (уопште), контакта очима, израза лица, положаја саговорника у простору, гестикулација и начина одевања. Анализа је показала да политичари до одређене мере контролишу своје појављивање у медијима, али да постоје специфичне ситуације у којима они несвесно реагују слањем непланиране, односно искрене поруке публици, коју би вероватно сакрили. За разлику од вербалне комуникације у којој можемо да користимо речи да сакријемо оно што стварно мислимо, сматра се да говор тела не може бити измишљен.
SPARASSODONTA (METATHERIA) COPROLITES FROM THE EARLY-MID MIOCENE (SANTACRUCIAN AGE) OF PATAGONIA (ARGENTINA) WITH EVIDENCE OF EXPLOITATION BY COPROPHAGOUS INSECTS
Authors: TOMASSINI RODRIGO L. , MONTALVO CLAUDIA I. , BARGO M.SUSANA , VIZCAÍNO SERGIO F. , CUITIÑO JOSÉ I. 
Published: December 2019

ABSTRACTCoprolites are a useful tool to obtain information related to the life history of the producer, trophic interactions, biodiversity, paleoenvironments, and paleoclimate, among other issues. We analyze here a sample of 111 coprolites recovered from levels of the Santa Cruz Formation (lower–middle Miocene, Burdigalian–early Langhian), outcropping in different localities of the Santa Cruz Province, Patagonian Argentina. Based on size and shape, two morphotypes were identified: coprolites assigned to morphotype I vary from ovoid to subspherical in shape, while coprolites assigned to morphotype II are cylindrical in shape. Several coprolites have bone and teeth inclusions belonging to small mammals (i.e., Octodontoidea and/or Chinchilloidea rodents). Morphometry, composition, and taphonomy of the bone remains suggest that the coprolites were produced by carnivorous mammals. According to the features of the guild of carnivorous mammals from the Santa Cruz Formation, we interpret that hathliacynids and/or small borhyaenoids (Sparassodonta) are the most probable producers. Different traces recorded in the coprolites, such as borings and putative eggs, suggest that the feces were exploited by coprophagous insects, probably dung beetles, for different purposes such as feeding and possible oviposition.
PALEOENVIRONMENTAL AND BIOSTRATIGRAPHIC IMPLICATIONS OF ECHINODERM OSSICLES TRAPPED WITHIN BURMESE AMBER
Authors: SALAMON MARIUSZ A. , LIN JIH-PAI , DUDA PIOTR , GORZELAK PRZEMYSŁAW , AUSICH WILLIAM I. , OJI TATSUO 
Published: December 2019

ABSTRACT
Marine organisms are uncommonly preserved in amber. Recently, they were reported to be associated with Burmese amber. However, most of specimens from previous reports were preserved on the amber surface or within the sediment surrounding the amber. Based on X-ray tomography and thin-section optical microscopy of Burmese amber, we report here the first genuine and unambiguous evidence of inclusion of crinoid ossicles preserved in the fossil resin. Preservation of this exclusively marine group in amber gives insights into the paleoenvironment of the crinoid-amber association and provides additional evidence to support previous observations of shallow-water stalked crinoids from the mid-Cretaceous, when many stalked crinoids started to shift offshore due to increased predation pressure during the Mesozoic Marine Revolution. Crinoid remains, represented by disarticulated stem and arm ossicles assignable to Isocrinus cf. legeri (Repelin), point to a mid-Cretaceous age for the Burmese amber and support some previous hypotheses suggesting a close proximity between the resin-producing trees and seawater.
Factors that influence the use of community assets by people with physical disabilities: results of participatory mapping in Envigado, Colombia.
Authors: Toro-Hernandez Maria Luisa , Villa-Torres Laura , Mondragón-Barrera Mónica Alejandra , Camelo-Castillo Wendy 
Published: December 2019

Abstract

Background: Disability is an evolving concept that results from the complex interaction between a person with an impairment and the context in which he/she lives. There is limited understanding on the types, access and use of community assets valuable for people with disabilities, and the role of contextual factors in Colombia. Our goal with this work was to identify the factors at the levels of the socio-ecological framework, and their interaction, that influence the use of community assets among people with physical disabilities and community stakeholders in Envigado, Colombia. Methods: Using participatory mapping, a community based participatory approach, we carried out an assessment of community assets identified by people with disabilities and rehabilitation professionals. In-depth interviews (n=32) informed the design of two participatory mapping activities, one among people with disabilities (n=5) and a second with rehabilitation professionals (n=4). Results were presented in a community forum to receive feedback on the findings. Results: Main findings indicate a chain of contextual factors that limit access and use of assets stemming from the personal (e.g. financial resources, inaccessible housing), interpersonal level (e.g. lack of a personal assistance or aid), and community levels (e.g. lack of accessible public transportation and inaccessible buildings). In most cases these barriers are heightened by system level barriers (e.g. lack of effective enforcement of the legal framework). Conclusions: Identifying these contextual factors, and their interactions, calls for stronger enforcement of the existing legal framework through articulated work between different stakeholders, so that people with disabilities can enjoy community assets.
Analysis of Affecting Factors on Patient Safety Culture in Public and Private Hospitals in Iran
Authors: khoshakhlagh amir hossein , Khatooni Elham , Akbarzadeh Isa , Yazdanirad Saeid , Sheidaei Ali 
Published: December 2019

Abstract
Background : Patient safety culture is one of the main components of the quality of health services and is one of the main priorities of health studies. Accordingly, this study aimed to determine and compare the views of healthcare staff on the patient safety culture and the impact of effective factors on patient safety culture in public and private hospitals in Tehran, Iran. Methods : This cross-sectional study was carried out on a sample of 1203 health care workers employed in three public and three private hospitals in Tehran, Iran. Stratified random sampling was used in this study. Data were collected using the Maslach burnout inventory and patient safety culture questionnaire (HSOPSC). IBM SPSS v22 and Amos v23 were used to perform path analysis. Results : 867 (72.57%) females and 747 (27.43%) males with a mean age of 33.88 ± 7.66 were included. The average percentage of positive responses to the safety culture questionnaire in public and private hospitals was 65.5% and 58.3%, respectively. The strengths of patient safety culture in public hospitals were in three dimensions including non-punitive response to errors (80%), organizational learning—continuous improvement (79.77%), and overall perceptions of patient safety (75.16%), and in private hospitals, were three dimensions including non-punitive responses to errors (71.41%), organizational learning & continuous improvement (69.24%), and teamwork within units (62.35%). The type of hospital and work-shift hours influenced the burnout and patient safety questionnaire scores (P-value <0.05). The path analysis results indicate the fitness of the proposed model (RMSEA= 0.024). The results showed a negative impact of a work shift (β= -0.791), occupational burnout (β= -0.554) and hospital type (β= -0.147) on the observance of patient safety culture. Conclusion: providing feedback on errors and requirements for the frequent incident reporting, and patient information exchange seem necessary to promote the patient safety culture. Also, considering the negative impact of the shift work and burnout on patient safety culture, by planning and managing these factors appropriately, correct actions could be designed to improve the safety culture. Keywords: Patient safety culture, shift work, job burnout, path analysis
A randomised controlled trial of hearing and vision support in dementia: Protocol for a process evaluation in the SENSE-Cog Trial
Authors: Leroi Iracema , Armitage Christopher J. , Collin Fidéline , Frison Eric , Hann Mark , Hooper Emma , Reeves David , Simkin Zoe , Wolski Lucas 
Published: December 2019

Abstract
Background: Optimising hearing and vision function may be important in improving a range of outcomes for people living with dementia (PwD) and their companions. The SENSE-Cog cross-national randomised controlled trial (RCT) is evaluating the effectiveness of a sensory intervention (SI) to improve quality of life for PwD with concurrent hearing and/or vision impairment, in five European countries. To ascertain how or why the intervention will, or will not, achieve its outcomes, we have designed a process evaluation to explore potential discrepancies between expected and observed outcomes. This will also help us to understand how context may influence the outcomes. Here we describe the protocol for this process evaluation, which is embedded within the RCT. Methods and analysis: We will use a mixed method approach with a theoretical framework derived from the UK Medical Research Council’s’ guidance on process evaluations. It will include the following: (1) evaluating how key aspects of the intervention will be delivered, which will be important to scale the intervention in real world populations; (2) characterising the contextual issues, which may shape the delivery and the impact of the intervention in different countries; and (3) investigating possible causal mechanisms through analyses of potential moderators and mediators. To avoid bias, we will analyse the process data before the analysis of the main effectiveness outcomes. Discussion: This evaluation will provide insight into how the complex SENSE-Cog SI will be tailored, enacted and received, across the different European contexts, all of which have unique health and social care economies. The findings will provide insight into the causal mechanisms effecting change, and will determine whether we should implement the intervention, if effective, on a wider scale for PwD and concurrent sensory impairment. Trial registration number: ISRCTN17056211. Registered on 19 February 2018. http://www.isrctn.com/ISRCTN17056211