bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceived Shame and Stigma, and Other Psychosocial Predictors of Psychological Distress Among Cancer Patients in Malaysia
Authors: Eyu Hui Ting , Nik Jaafar Nik Ruzyanei , Leong Abdullah Mohammad Farris Iman , Salleh Salimi Hajar Mohd , Mohamad Yunus Mohd Razif , Ismail Fuad , Ab Muin Nur Fa'izah , Abdul Aziz Noor Syazwani 
Published: December 2024

ABSTRACTBackgroundPatients' sociodemographic factors, clinical characteristics, distress factors, perceived shame and stigma may give rise to psychological distress in cancer patients that bring about further psychosocial impact.Aims(1) to determine the degrees of shame and stigma towards cancer and psychological distress among cancer patients in Malaysia and (2) to examine the clinical and psychosocial predictors of psychological distress.MethodsThis cross‐sectional study recruited a total of 217 cancer patients. The participants were administered the sociodemographic and clinical characteristics questionnaires, the Malay version of the Shame and Stigma Scale (SSS‐M) to assess for the degree of cancer shame and stigma, and the Malay version of the Distress Thermometer and Problem List to assess for presence of psychological distress and identify its sources.ResultsThere was a significant level of shame and stigma among cancer patients with the total mean SSS‐M score of 12.08 (SD = 6.09). Anger (adjusted odds ratio [AOR] = 11.97, 95% confidence interval [CI] = 2.96–86.8, p = 0.001), loss of interest or enjoyment (AOR = 14.84, 95% CI = 2.93–75.20, p = 0.001), loneliness (AOR = 8.10, 95% CI = 1.13–58.02, p = 0.001), feeling of worthlessness or being a burden (AOR = 6.24, 95% CI = 1.32–29.59, p = 0.021), fear (AOR = 4.52, 95% CI = 1.79–11.43, p = 0.001), pain (AOR = 4.07, 95% CI = 1.53–10.82, p = 0.005), financial constraint (AOR = 2.95, 95% CI = 1.22–7.13, p = 0.016), and having regret (AOR = 1.89, 95% CI = 1.03–3.79, p = 0.039) increased the odds of developing psychological distress.ConclusionTreating clinicians should monitor for and provide psychosocial interventions for the biopsychosocial factors which may worsen psychological distress among cancer patients.
Geographical Origin, Internal Migration and Labour Market Attainment: An Analysis of Employment Opportunities and Class Attainment Among Italian Men and Women
Authors: Panichella Nazareno 
Published: December 2024

ABSTRACTThis article examines how the uneven development of Southern and Northern Italian occupational structures influences the occupational outcomes of Southern, Northern and internal migrants. By employing a gender‐sensitive approach and analysing the distribution of the effects of geographical mobility on occupational attainment over the life course, the study enhances understanding of the interplay between social and geographical factors contributing to social inequality. The findings reveal that the South–North dualism significantly affects employment opportunities, with Northern Italians enjoying substantial advantages, particularly among women. Contrary to international literature suggesting that internal migration benefits men but harms women, this study finds positive outcomes for both genders. However, while male internal migrants experience immediate employment returns in the labour market, increasing their chances of being in both the white‐collar and working classes, female internal migrants integrate more gradually and face a higher likelihood of being employed in the working class.
Integrative multi‐omics reveals the mechanism of ulcerative colitis treated with Ma‐Mu‐Ran antidiarrheal capsules
Authors: Huang Hailing , Duan Bailu , Huang Zhuang , Wang Shanshan , Wen Yuxin , Jiang Qi , Chen Pengyu , Huang Ping , Liu Jiajing , Zheng Sili , Ye Yan , Zhang Dongning , Wang Qiong , Huang Fang , Li Jingjing , Han Lintao 
Published: December 2024

RationaleUlcerative colitis (UC) is a chronic inflammatory gastrointestinal disease typically coexisting with intestinal microbiota dysbiosis, oxidative stress, and an inflammatory response. Although its underlying mechanism of action is unclear, Ma‐Mu‐Ran Antidiarrheal Capsules (MMRAC) have demonstrated significant therapeutic efficacy for UC.MethodsThe mechanism of action of MMRAC in the treatment of UC model was investigated by combining metabolomics, transcriptomics, and intestinal microbiota detection techniques.ResultsThe high‐dose group of MMRAC was determined as the best therapeutic dose by pathological changes and biochemical indexes. Transcriptome analysis revealed that 360 genes were differentially altered after MMRAC treatment. Metabolomic analysis using colon tissue yielded 14 colon tissue metabolites with significant differences. Intestinal flora analysis showed that 26 major microorganisms were identified at the genus level.ConclusionsBased on a thorough multi‐omics analysis of transcriptomics, metabolomics, and gut flora, it was determined that MMRAC regulated cysteine and methionine metabolism, arginine biosynthesis, and sphingolipid metabolism and their respective genes BHMT, PHGDH, iNOS, and SPHK1, which in turn served to inhibit UC‐generated inflammatory responses and oxidative stress. Additionally, MMRAC regulated the abundance of Coprococcus, Helicobacter, Sutterella, Paraprevotella, and Roseburia in the intestinal tracts of UC mice, which was regulated toward normal levels, thereby restoring normal intestinal function.
A Redox‐Triggered Polymeric Nanoparticle for Disrupting Redox Homeostasis and Enhanced Ferroptosis
Authors: Li Yifei , Han Shangcong , Zhao Yi , Yan Jianqin , Luo Kui , Li Fashun , He Bin , Sun Yong , Li Fan , Liang Yan 
Published: December 2024

AbstractCancer cells possess an efficient redox system, enabling them to withstand oxidative damage induced by treatments, especially in hypoxia areas and ferroptosis can disrupt redox homeostasis in cancer cell. Herein, GSH‐sensitive nanoparticles are constructed that induce ferroptosis by long‐lasting GSH depletion and enhanced PDT. Carbonic anhydrase IX inhibitor, protoporphyrin IX (Por) complexed with Fe and epirubicin (EPI) are grafted to hyaluronic acid (HA) via disulfide bonds to obtain HSPFE and loaded xCT inhibitor SAS for fabricating SAS@HSPFE which is actively targeted to deep hypoxic tumor cells, and explosively releasing EPI, Por‐Fe complex and SAS due to at high GSH concentration. Specifically, SAS inhibited the GSH biosynthesis, and the generation of ROS by Por and the involvement of Fe2+ in the Fenton reaction jointly facilitates oxidative stress. Besides, Fe2+ reacted with excess H2O2 to produce O2, which continuously fuels PDT. GPX4 and SLC7A11 related to antioxidant defense are down‐regulated, while ACSL4 and TFRC promoting lipid peroxidation and ROS accumulation are up‐regulated, which enhanced ferroptosis by amplifying oxidative stress and suppressing antioxidant defense. SAS@HSPFE NPs revealed highly efficient antitumor effect in vivo study. This study provides a novel approach to cancer treatment by targeting redox imbalance.
Confined Synthesis of 2D Molybdenum Diphosphide Nanosheets via Gas‐Solid Transformation
Authors: Wang Wenbin , Wu Jingkun , Ma Chen , Qi Junlei , Bao Kai , Zhai Li , Repaka D. V. Maheswar , Han Xiao , Ma Cong , Wu Zongxiao , Wang Lingzhi , Gong Feng , Liu Yingxia , Chen Ye , He Qiyuan 
Published: December 2024

AbstractMolybdenum diphosphide (MoP2), a topological semimetal, possesses distinctive properties and applications in catalysis, energy storage, and condensed matter physics. However, synthesizing high‐purity MoP2 is complex and often results in undesired stoichiometric by‐products. Additionally, the intrinsic orthorhombic crystal structure makes it difficult to synthesize MoP2 in a 2D morphology, which is desirable for device and energy applications. Here, the robust synthesis of MoP2 with a well‐defined 2D morphology is achieved using the confined gas‐solid phosphorization of a MoS2 precursor on substrates. The use of 2D precursors and the surface confinement provided by the substrate maintain the 2D morphology and result in a thickness‐dependent stoichiometry of the phosphorization products. The chemical composition and crystal structure of MoP2 nanosheets are comprehensively characterized. At room temperature, MoP2 nanosheets exhibit metallic transport with high conductivity over 5500 S cm−1. Furthermore, MoP2 nanosheets demonstrate excellent electrocatalytic activity and durability for hydrogen evolution in both neutral and acid mediums. Notably, MoP2 nanosheets possess better durability than amorphous Pt film and commercial Pt/C, positioning MoP2 as a promising catalyst for hydrogen evolution in neutral mediums. This work advances the synthetic chemistry of 2D MoP2 and provides 2D semimetals with a novel member for future explorations in diverse fields.
Transition Metal Complex‐Loaded Nanosystems: Advances in Stimuli‐Responsive Cancer Therapies
Authors: Das Bishnu 
Published: December 2024

AbstractTransition metal complex‐loaded nanosystems (TMCNs) represent a cutting‐edge platform for stimuli (light, ultrasound)‐responsive cancer therapies. These nanosystems, incorporating metals such as manganese(II), zinc(II), ruthenium(II), rhenium(I), iridium(III), and platinum(IV), significantly enhance the efficacy of light‐activated therapies, including photodynamic therapy (PDT) and photothermal therapy (PTT), as well as ultrasound‐activated treatments like sonodynamic therapy (SDT). TMCNs based on ruthenium(II), rhenium(I), and iridium(III) improve PDT, while manganese(II) and iridium(III) demonstrate exceptional sonosensitizing properties. In PTT, ruthenium(II) and iridium(III)‐based TMCNs efficiently absorb light and generate heat. Emerging synergistic approaches that combine SDT, PTT, PDT, chemotherapy, and immunotherapy are demonstrated to be powerful strategies for precision cancer treatment. Zinc(II), ruthenium(II), iridium(III), and platinum(IV)‐based TMCNs play a critical role in optimizing these therapies, enhancing tumor targeting, and reducing side effects. Furthermore, TMCNs can amplify immunotherapy by inducing immunogenic cell death, thus strengthening the immune response. These advances address key challenges such as tumor hypoxia and therapeutic resistance, opening new possibilities for innovative photosensitizer‐based cancer treatments. This review highlights the latest progress in TMCNs design and applications, demonstrating their potential to revolutionize stimuli‐responsive cancer therapies.
Seasonal and daily use of canal culverts by mammals, reptiles, amphibians, and invertebrates
Authors: Hamilton Kaela M. , Bommarito Thomas , Bateman Heather L. , Lewis Jesse S. 
Published: December 2024

AbstractLandscape connectivity is critical to the long‐term conservation of wildlife populations. Although anthropogenic linear infrastructures (ALI), including roads and canals, provide important resources to humans, they can affect wildlife through habitat fragmentation and reduced movement through landscapes. To increase landscape connectivity, crossing structures, including underpasses, can facilitate wildlife movement across landscapes experiencing ALI. However, little is known about how a suite of small‐ to medium‐sized species use underpasses across seasonal and daily time periods, especially for some ALI such as major canals. We used specialized camera technology (i.e., the Hobbs Active Light Trigger [HALT] camera) to evaluate use of culvert underpass crossing structures (hereafter culverts) along the Central Arizona Project canal, Arizona, by a suite of mammals, reptiles, amphibians, and invertebrates. Specifically, we evaluated (1) which wildlife species used culverts, (2) how the frequency of use varied across seasons (i.e., hot‐dry, hot‐wet, cool‐wet) and (3) daily activity patterns of wildlife using culverts. We detected 31 species of wildlife using culverts, which included small‐ to medium‐sized mammals (56.4% of crossings), reptiles (21.0% of crossings), amphibians (19.0% of crossings), and invertebrates (3.6% of crossings), including some species of conservation concern, such as the Sonoran Desert tortoise (Gopherus morafkai) and Gila monster (Heloderma suspectum). However, crossings by larger mammal species were less effectively detected with the HALT cameras. Reptile crossing frequency was similar between the 2 seasons that they were active during the hot‐dry (May–June) and hot‐wet (July–October) seasons and crossing frequency by some species of amphibians and invertebrates was higher in the hot‐wet season. Throughout the entire year, small mammals used culverts more frequently in hot seasons (i.e., hot‐wet and hot‐dry) compared to the cool‐wet (November‐March) season. In addition, daily activity patterns varied by species, where species crossed culverts during diurnal (e.g., desert spiny lizards, Sceloporus magister and coachwhip snakes, Masticophis flagellum), crepuscular (e.g., cottontail rabbits, Sylvilagus audubonii and western diamondback rattlesnakes, Crotalus atrox), and nocturnal (e.g., deer mouse species, heteromyid species, woodrat species, desert stink beetle species) time periods. Our information can be used to manage wildlife crossing areas and increase landscape connectivity in relation to ALI.
A log story short: running contributions to radiative Higgs decays in the SMEFT
Authors: Grojean Christophe , Guedes Guilherme , Nepveu Jasper Roosmale , Salla Gabriel M. 
Published: December 2024

Abstract
We investigate the renormalization of the radiative decays of the Higgs to two gauge bosons in the Standard Model Effective Field Theory at mass dimension eight. Given that these are loop-level processes, their one-loop renormalization can be phenomenologically important when triggered by operators generated through the tree-level exchange of heavy particles (assuming a weakly coupled UV model). By computing the tree-level matching conditions of all relevant extensions of the Standard Model, we demonstrate that this effect is indeed present in the h → γZ decay at dimension eight, even though it is absent at dimension six. In contrast, the h → gg and h → γγ decays can only be renormalized by operators generated by one-loop processes. For UV models with heavy vectors, this conclusion hinges on the specific form of their interaction with massless gauge bosons which is required for perturbative unitarity. We study the quantitative impact of the possible logarithmic enhancement of h → γZ, and we propose an observable to boost the sensitivity to this effect. Given the expected increased precision of next-generation high-energy experiments, this dimension-eight contribution could be large enough to be probed and could therefore give valuable clues about new physics by revealing some of its structural features manifesting first at dimension eight.
Measurement of CKM element |Vcb| from W boson decays at the future Higgs factories
Authors: Liang Hao , Li LingFeng , Zhu Yongfeng , Shen Xiaoyan , Ruan Manqi 
Published: December 2024

Abstract
This study investigates the precision measurement of the CKM matrix element |Vcb| through semileptonic WW events at future Higgs factories, i.e., FCC-ee, ILC, C3, and CEPC. We use full detector simulation to generate the WW → ℓνcb signal events and various backgrounds at $$ \sqrt{s} $$

s

= 240 GeV with unpolarized beams. The relative statistical uncertainties of |Vcb| are projected to be 0.91% for the muon channel and 1.2% for the electron channel, assuming a baseline integrated luminosity of 5 ab−1. The sensitivities at other Higgs factory scenarios are also projected. Possible contributors to systematic uncertainties are discussed, with the most prominent one being the systematics of flavor-tagging and mistagging rates. Combining with WW threshold runs, the relative systematic uncertainty can be further reduced.
Modular flavored dark matter
Authors: Baur Alexander , Chen Mu-Chun , Knapp-Pérez V. , Ramos-Sánchez Saúl 
Published: December 2024

Abstract
Discrete flavor symmetries have been an appealing approach for explaining the observed flavor structure, which is not justified in the Standard Model (SM). Typically, these models require a so-called flavon field in order to give rise to the flavor structure upon the breaking of the flavor symmetry by the vacuum expectation value (VEV) of the flavon. Generally, in order to obtain the desired vacuum alignment, a flavon potential that includes additional so-called driving fields is required. On the other hand, allowing the flavor symmetry to be modular leads to a structure where the couplings are all holomorphic functions that depend only on a complex modulus, thus greatly reducing the number of parameters in the model. We show that these elements can be combined to simultaneously explain the flavor structure and dark matter (DM) relic abundance. We present a modular model with flavon vacuum alignment that allows for realistic flavor predictions while providing a successful fermionic DM candidate.
Reciprocal non-relativistic decoupling limits of String Theory and M-Theory
Authors: Lambert Neil , Smith Joseph 
Published: December 2024

Abstract
It has recently been realised that there are supersymmetry-preserving non-relativistic decoupling limits associated with each half-BPS object in String Theory and M-Theory. We argue that, given a p-brane and a q-brane for which there is a quarter-BPS intersecting configuration, the p-brane decoupling limit of the q-brane’s worldvolume QFT is necessarily equal to the reciprocal q-brane decoupling limit of the p-brane’s worldvolume theory. This is explicitly shown for the cases of the D0-D4 and D1-D3 systems. As an application of this idea, we use the reciprocal pair of limits in the M2-M5 system to describe the dynamics of interacting self-dual strings in the six-dimensional $$ \mathcal{N} $$
N
= (2, 0) theory. We also discuss the limits of the dual gravitational theories and, using symmetries, argue that the duality is maintained by the limits.
Proving the absence of large one-loop corrections to the power spectrum of curvature perturbations in transient ultra-slow-roll inflation within the path-integral approach
Authors: Kawaguchi Ryodai , Tsujikawa Shinji , Yamada Yusuke 
Published: December 2024

Abstract
We revisit one-loop corrections to the power spectrum of curvature perturbations ζ in an inflationary scenario containing a transient ultra-slow-roll (USR) period. In ref. [1], it was argued that one-loop corrections to the power spectrum of ζ can be larger than the tree-level one within the parameter region generating the seeds of primordial black holes during the USR epoch, which implies the breakdown of perturbation theory. We prove that this is not the case by using a master formula for one-loop corrections to the power spectrum obtained in ref. [2]. We derive the same formula within the path-integral formalism, which is simpler than the original derivation in [2]. To show the smallness of one-loop corrections, the consistency relations and the effective constancy of tree-level mode functions of ζ for super-Hubble modes play essential roles, with which the master formula gives a simple expression for one-loop corrections. For concreteness, we provide a reduced set of interactions including the leading-order one, while establishing the consistency relations in a self-consistent manner. We also show how the consistency relations of various operators hold explicitly, which plays a key role in proving the absence of large one-loop corrections.
On Disjoint Dynamical Properties and Lipschitz-Free Spaces
Authors: Cobollo Ch. , Peris A. 
Published: December 2024

Abstract
The notion of disjoint

$$\mathcal {A}$$

A

-transitivity for a Furstenberg family

$$\mathcal {A}$$

A

is introduced with the aim to generalize properties derived from disjoint hypercyclic operators. We begin a systematic study by showing some of the basic properties, including necessary conditions to inherit the property on the whole space from an invariant linearly dense set containing the origin. As a consequence, we continue the study of the link between non-linear and linear dynamics through Lipschitz-free spaces by presenting some necessary conditions to obtain disjoint

$$\mathcal {A}$$

A

-transitivity for families of Lipschitz-free operators on

$$\mathcal {F}(M)$$

F
(
M
)

expressed in terms of conditions in the underlying metric space M.
Autofreefem: automatic code generation with FreeFEM and LaTex output for shape and topology optimization of non-linear multi-physics problems
Authors: Allaire Grégoire , Gfrerer Michael H. 
Published: December 2024

AbstractFor an educational purpose, we develop the Python package AutoFreeFEM which generates all ingredients for shape optimization with non-linear multi-physics in FreeFEM and also outputs the expressions for use in LaTeX. As an input, the objective function and the weak form of the problem have to be specified only once. This ensures consistency between the simulation code and its documentation. In particular, AutoFreeFEM provides the linearization of the state equation, the adjoint problem, the shape derivative, as well as a basic implementation of the level-set based mesh evolution method for shape optimization. For the computation of shape derivatives, we utilize the mathematical Lagrangian approach for differentiating PDE-constrained shape functions. Differentiation is done symbolically using SymPy. In numerical experiments, we verify the accuracy of the computed derivatives. Finally, we showcase the capabilities of AutoFreeFEM by considering shape optimization of a non-linear diffusion problem, linear and non-linear elasticity problems, a thermo-elasticity problem, and a fluid–structure interaction problem.
New model to predict thermomagnetic properties of nanostructured magnetic compounds
Authors: Gokhfeld Denis , Koblischka Michael Rudolf , Koblischka-Veneva Anjela 
Published: December 2024

Abstract
The development of new materials showing the magneto-caloric effect (MCE) requires fast and reliable characterization methods. For this purpose, a phenomenological model developed by M. A. Hamad has proven to be a useful tool to predict the magnetocaloric properties (the isothermal magnetic entropy change,

$$\Delta S_\textrm{M}$$

Δ

S
M

, the magnetization-related change of the specific heat,

$$\Delta C_{P,H}$$

Δ

C

P
,
H

, and the relative cooling power, RCP) via calculation from magnetization measurements as a function of temperature, M(T). However, fitting the M(T) data is difficult for broad, smoothed-out transition curves which are often observed for material systems such as core-shell nanoparticles, nanowires, nanowire fabrics or nanoparticle hybrid materials. Thus, in this contribution we present a different approach enabling proper fitting of such magnetization data via the use of an asymmetric Boltzmann sigmoid function, which provides a clear physical background and enables to properly describe the broad and smoothed out transitions of nanomaterials. As examples for our procedure, we present fits to M(T) curves of polycrystalline, bulk

$$\hbox {La}_{0.67}\hbox {Ba}_{0.33}\hbox {MnO}_3$$

La

0.67

Ba

0.33

MnO
3

as well as

$$\hbox {La}_{1-x}\hbox {Sr}_{x}\hbox {MnO}_3$$

La

1
-
x

Sr
x

MnO
3

(

$$x=$$

x
=

0.2, 0.3, 0.4) and

$$\hbox {La}_{0.7}\hbox {Ca}_{0.3}\hbox {MnO}_3$$

La

0.7

Ca

0.3

MnO
3

nanostructured materials from various authors.