bluuebunny/crossref_metadata_2025_split huggingface dataset:
GONGOCOMPOSTO: SUBSTRATO ORGÂNICO PROVENIENTE DE RESÍDUOS DE PODA PARA PRODUÇÃO DE MUDAS DE ALFACE
Authors: Bugni Nathalia Oliveira Cruz , Antunes Luiz Fernando de Sousa , Marinho Guerra José Guilherme , Fernandes Correia Maria Elizabeth 
Published: July 2020

O substrato constitui-se em um dos fatores limitantes à produção de mudas, tornando-se importante o constante desenvolvimento de tecnologias que possibilitem produzir substratos a partir de materiais renováveis e de baixo custo. Este trabalho objetivou avaliar a eficiência dos substratos orgânicos obtidos pela gongocompostagem mediada pelo diplópode Trigoniulus corallinus, na produção de mudas de alface crespa. Os resíduos empregados na gongocompostagem foram os galhos finos e folhas de quatro espécies arbóreas: Terminalia catappa (Amendoeira), Licania tomentosa (Oiti), Senna siamea (Cassia), Albizia lebbeck (Albizia), os quais foram compostados por 120 dias. Os substratos gerados foram caracterizados quanto às suas propriedades físicas, físico-químicas e químicas. O delineamento experimental adotado foi o inteiramente casualizado, com 12 tratamentos e cinco repetições, dispostos em arranjo fatorial 6x2 (substratos com e sem adição de farelo de mamona). Aos 21 dias após a semeadura avaliou-se a massa fresca e seca da parte aérea, massa fresca e seca de raízes, o vigor da muda e estabilidade do torrão. A análise física e química dos gongocompostos revelou que as características se encontravam dentro de níveis adequados ao emprego como substratos. Os gongocompostos proporcionaram crescimento de parte aérea e de raízes semelhantes entre si, todavia, quando o farelo de mamona foi adicionado aos gongocompostos, as produções de parte aérea e de raízes foram otimizadas, sobretudo no substrato constituído de Licania tomentosa e Albizia lebbeck, que proporcionou a obtenção de mudas com vigor maior do que o substrato SIPA e menor apenas do que o substrato comercial avaliado.
Inclusion of innovative technology in integrated waste management of a city: case of Bogura, Bangladesh
Authors: Dey D. , Krukkert I. , Osse E. 
Published: July 2020

Abstract
Bogura is the largest municipality in Bangladesh by population. Its huge population and agri-industry produces a great deal of solid, faecal and industrial waste which has been a matter of concern for the municipality. IRC started working for a solution and completed a pre-feasibility and feasibility study to find innovative technologies and an operation model. The feasibility study has produced an integrated solution of faecal sludge, municipal solid waste, agri-waste and aerosol can recycling model which also helps to reduce surface and ground water contamination. The solution integrates conventional anaerobic digestion with new torrefaction and aerosol-propellant capture technologies which treats the municipality solid waste and aerosol cans to produce biofuel and liquid petroleum gas, respectively.
Biosorption of organic micropollutants onto lignocellulosic-based material
Authors: Alves Thiago Caique , Mota João André Ximenes , Pinheiro Adilson 
Published: July 2020

Abstract
The occurrence of organic micropollutants such as pharmaceutical drugs and hormones in the environment reflects the inefficiency of traditional wastewater treatment technologies. Biosorption is a promising alternative from a technical-economic point of view, so understanding the mechanisms of adsorption in new biosorbents is vital for application and process optimization. Within this context, this study aims to evaluate the mechanisms of adsorption and removal of synthetic and natural hormones by Pinus elliottii bark biosorbent (PS) compared to commercial granular activated carbon (GAC) through kinetic models, isotherm models, and thermodynamic models. The adsorbents were also characterized by morphology, chemical composition, functional groups, and point of zero charge. Characterization of the adsorbents highlights the heterogeneous and fibrous morphology and broader range of functional groups found for PS. Kinetic adjustments showed high accuracy for pseudo-second-order, Elovich, and intraparticle diffusion models, presenting multilinearity and evidencing multi-stage adsorption. The isotherms for PS followed high-affinity models, predominantly chemisorption, while those for GAC followed the Langmuir model, where physisorption predominates. These mechanisms were confirmed by thermodynamic models, which also indicated a higher dependence on temperature in the adsorption process. In the fortified water removal test, PS showed removal values higher than GAC, highlighting the advantages of this adsorbent.
Investigation of Targeting Relationship between Micro-Rna-22 and Vegfr3 in Lung Squamous Cell Carcinoma
Authors: Dong Zheng , Xu Qing-Hua , Zhu Yuan-Bin , Wang Yong-Feng , Xiong Jie , Dang Shuai 
Published: July 2020

Aims :
The present study explored the clinical significance of microRNA-22 (miR-22)
expression in lung squamous cell carcinoma and to explore the targeting relationship with vascular
endothelial growth factor receptor 3 (VEGFR3).

Methods:
A total of 49 patients with lung squamous cell carcinoma who underwent surgical
treatment were selected. The expression of miR-22 was detected by fluorescence quantitative realtime
PCR (qPCR), the expression of VEGFR3 was detected by Western blotting assays, and D240
labeled microlymphatic vessels density (MLVD) was detected by immunohistochemistry (IHC).
Lung squamous cell carcinoma cell line SK-MES-1 was selected and the targeting relationship
between miR-22 and VEGFR3 was analyzed by double luciferase reporter gene assay. Western
blotting assays were used to detect the expression of vascular endothelial growth factor-D (VEGFD)
and D240 in the blank control group, empty vector transfection group, miR-22 transfection
group, miR-22 and VEGFR3 co-transfection group.

Results:
The expression range of miR-22 in lung squamous cell carcinoma was 0.8-3.5. The
expression of miR-22 in lung squamous cell carcinoma was significantly different by tumor
maximum diameter, lymph node metastasis, vascular invasion and TNM stage. The expression of
miR-22 was linked to survival time. There was a negative correlation between miR-22 and
VEGFR3, miR-22 and MLVD. Double luciferase reporter gene assays showed that miR-22
reduced the luciferase activity of pGL3-VEGFR3-WT transfected cells. Compared with the control
group, the expression of VEGF-D and D2-40 in the miR-22 transfection group was significantly
decreased. However, VEGF-D and D240 in the miR-22 and VEGFR3 co-transfection group
reversed the changes.

Conclusion:
We assumed that the abnormal expression of miR-22 in lung squamous cell
carcinoma may be involved in the development and progression of lung squamous cell carcinoma.
MiR-22 negatively regulated the target gene VEGFR3 to mediate lymphangiogenesis. The
expression of miR-22 may also be linked to the prognosis of the disease.
Proliferative Effect of FadA Recombinant Protein from Fusobacterium nucleatum on SW480 Colorectal Cancer Cell Line
Authors: Dadashi Masoud , Hajikhani Bahareh , Faghihloo Ebrahim , Owlia Parviz , Yaslianifard Somayeh , Goudarzi Mehdi , Nasiri Mohammad Javad , Fallah Fatemeh 
Published: July 2020

Background and Aim:
Colorectal Cancer (CRC) is one of the most frequent cancers diagnosed
in both men and women worldwide. Fusobacterium nucleatum adhesin A (FadA) has an
important potential factor in the development or progression of CRC. The aim of the present study
was to evaluate the proliferative effect of recombinant FadA on SW480 colorectal cancer cell line.

Materials and Methods:
The recombinant pET21(b)-fadA plasmid was synthesized and transformed
into competent E.coli DH5α. In the next step, induction and expression of recombinant FadA
were carried out in E. coli BL21 (DE3) competent cells. Expression and purification of protein
were successfully done and it was analyzed and confirmed by SDS-PAGE and western blotting.
The proliferative effect of purified FadA on SW480 CRC cell line was evaluated using MTT assay
and cell counting methods.

Results:
Visualization of the specific band isolated from the linear plasmid on the agarose gel confirmed
the presence of the desired gene. After electrophoresis and Coomassie blue staining, the protein
of interest with an approximate molecular weight of 13KDa was detected. The MTT assay,
similar to cell counting methods, revealed that FadA dose and time-dependently promoted SW480
cell growth and proliferation in 24, 48 and 72 hours.

Conclusion:
The results showed that FadA stimulates proliferation of SW480 colorectal cancer
cell line with a dose and time-dependent manner.
An Experience with Delamanid in an XDR TB Case – Case Report
Authors: Mohan Nimitha , Kaur Manharpreet , Singhal Lipika , Saini Varinder , Chander Jagdish 
Published: July 2020

Introduction:
Tuberculosis is an endemic infection and a serious public health problem
in India. India constitutes one-fourth of the global TB population. The emerging drug resistance is
a major threat to global tuberculosis care and control.

Case report:
We present an experience with a case of newly diagnosed microbiologically confirmed, extremely drug resistant primary pulmonary tuberculosis who was treated with delamanid and found to be cured of tuberculosis.

Discussion:
Delamanid is a new anti-tubercular drug, which is thought to primarily inhibit the synthesis
of methoxy-mycolic, and keto-mycolic acid, which are components of the mycobacterial cell
wall. In our patient who was a newly diagnosed case of MDR-TB converted to XDR-TB in little
course of time and we were successful in treating him with Delamanid therapy. His sputum culture
conversion was achieved in 20 days. Even though the patient did not tolerate well because of the
side effects of the drug, still he became microbiologically negative for tuberculosis.

Conclusion:
Delamanid fulfills many target criteria for new TB drugs and may be particularly useful
for the treatment of MDR-TB. It can be administered orally and its bactericidal properties make
it suitable in regimens designed to shorten treatment duration. Clinical efficacy data, while limited,
are reassuring.
Reproductive, Lifestyle, and Genetic Risk Factors in Breast Cancer Among Iranian Women- A Cross-sectional Study During the Breast Cancer Screening in a Community in Iran
Authors: Vakilian Katayon , Mohaghegh Pegah , Mirzaei Fatemeh , Taheri Majd , Zahiri Rita , Roozbahani Nasrin 
Published: July 2020

Aim:
Breast cancer is one of the most common malignancies in women. The present study is aimed to investigate the risk factors of this disease among the Iranian women of Arak city.

Background:
Breast cancer is one of the most common malignancies in women.

Objective:
To study the reproductive, lifestyle, and genetic risk factors.

Methods:
This cross-sectional study was conducted in Arak city. The sampling was conducted in a clustering method in a way that 4 health centers (surveying cancer in the country; October 2018 to March 2019) were investigated. The women willing to fill up the breast cancer risk factors were entered into the research. 1000 women (above 18) were included. After filling the questionnaires, the data were analyzed by SPSS Ver. 21 using descriptive statistics such as percentage and mean values.

Results:
4% of the participants (40) had a history of breast cancer among their first-degree relatives. Only 1.9% (19) of the women reported eating fast-food twice a day. 1.7% (16) of the studied women drank alcohol in the last month. 70.3% of the women (691) had children with an average age at first birth of 22.32±4.87. 1.3% (13) of the participants were under hormone-therapy during their menopause, with an average duration of 4±6.87 years.

Conclusion:
It seems that the risk factors of breast cancer are not low among Iranian women. Screening tests such as self-examination of the breasts and periodic examinations by the physicians or midwives as well as the mammography protocols are essential
A diagnosis of difficulties in answering questions of circle material on junior high school students
Authors: Abidin Minhajjul , Retnawati Heri 
Published: July 2020

This research is aimed at describing (1) the characteristics of items about a diagnostic test of circle material in mathematics, (2) how significant the percentage of students' types of errors in answering the questions, and (3) the diagnosis of students' difficulties in answering the questions based on DINA model. This research is quantitative descriptive research involving eighth graders of junior high school in East Lombok regency as the population. The sample was chosen by a proportionate random sampling technique, consisting of 105 students for preliminary field testing and 416 students for main field testing. The instrument of this study was a diagnostic test using a four-option multiple-choice format. Data on students' responses were analyzed using the R program with CDM (Cognitive Diagnostic Model) DINA model, which requires underlying attributes for each item. The results show that: (1) the diagnostic test instrument had met the qualitative and quantitative content validity; (2) the percentage of students' answers retrieved from the conceptual error is 18.47%, 9.99% is interpretation error, the procedural error is 7.80%, and counting error is 14.57%; (3) based on the results of the analysis with DINA model, students' error in answering the questions of the circle material in mathematics are dominantly caused by students' lack of mastery on solving problems associated to the circumference of a circle, that is, (A28) the ability to calculate the length of a path, and (A29) the ability to calculate many rounds on wheels.
Telerehabilitation for Patients With Knee Osteoarthritis: A Focused Review of Technologies and Teleservices
Authors: Naeemabadi MReza , Fazlali Hesam , Najafi Samira , Dinesen Birthe , Hansen John 
Published: July 2020

Background
Telerehabilitation programs are designed with the aim of improving the quality of services as well as overcoming existing limitations in terms of resource management and accessibility of services. This review will collect recent studies investigating telerehabilitation programs for patients with knee osteoarthritis while focusing on the technologies and services provided in the programs.

Objective
The main objective of this review is to identify and discuss the modes of service delivery and technologies in telerehabilitation programs for patients with knee osteoarthritis. The gaps, strengths, and weaknesses of programs will be discussed individually.

Methods
Studies published in English since 2000 were retrieved from the EMBASE, Scopus, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), PubMed, Physiotherapy Evidence Database (PEDro), and PsycINFO databases. The search words “telerehabilitation,” “telehealth,” “telemedicine,” “teletherapy,” and “ehealth” were combined with “knee” and “rehabilitation” to generate a data set of studies for screening and review. The final group of studies reviewed here includes those that implemented teletreatment for patients for at least 2 weeks of rehabilitation.

Results
In total, 1198 studies were screened, and the full text of 154 studies was reviewed. Of these, 38 studies were included, and data were extracted accordingly. Four modes of telerehabilitation service delivery were identified: phone-based, video-based, sensor-based, and expert system–based telerehabilitation. The intervention services provided in the studies included information, training, communication, monitoring, and tracking. Video-based telerehabilitation programs were frequently used. Among the identified services, information and educational material were introduced in only one-quarter of the studies.

Conclusions
Video-based telerehabilitation programs can be considered the best alternative solution to conventional treatment. This study shows that, in recent years, sensor-based solutions have also become more popular due to rapid developments in sensor technology. Nevertheless, communication and human-generated feedback remain as important as monitoring and intervention services.
Alas Kandung-based science learning tools to optimize students’ critical thinking skills
Authors: Ratnasari Novita , Sarwanto S. , Prayitno Baskoro Adi 
Published: July 2020

Critical Thinking Skills (CTS) are the crucial skills required by nowadays generation in dealing with the 21st Century challenges. Yet, the researches focused on higher order thinking skills are still limited. This study aimed to analyze the effect of Alas Kandung-based science learning tools on students’ CTS. The research design was pretest and post-test with non-equivalent control group. The treatment given in experimental class was the implementation of Alas Kandung-based science learning tools, while the control class was taught using common method used by the teachers. The results of this study indicated that the students’ CTS in experimental class was significantly higher than the control class [F(1,47) = 11.672, p = 0.001]. In conclusion, the Alas Kandung-based science learning tools is effective in improving students’ CTS.
SINTOMAS NEUROLÓGICOS E EXPOSIÇÃO À RADIAÇÃO ELETROMAGNÉTICA DA TELEFONIA CELULAR
Authors: Silva Denize Francisca da , Rocha André Luís Cruz da , Rêgo Marco Antônio Vasconcelos , Almeida Maria da Conceição Chagas de 
Published: July 2020

A tecnologia de comunicação sem fio, embora produza benefícios à exposição à radiação da telefonia celular, tem aumentado a preocupação da comunidade científica e sociedade em geral devido à possibilidade de efeitos adversos na saúde humana. Este artigo tem como objetivo investigar a associação entre exposição à radiação eletromagnética não ionizante (Reni) decorrente da estação radiobase de telefonia celular (TC) e sintomas neurológicos na população residente nos bairros do Bonfim e Monte Serrat do município de Salvador/BA. Em um estudo transversal realizado em Salvador/BA, entrevistaram-se 440 indivíduos. Queixas neurológicas constituíram as variáveis dependentes. Realizou-se análise de regressão logística hierarquizada para avaliação de confundimento. Observou-se associação entre sintomas neurológicos e formas de uso do telefone celular (mais de 30 min/dia, com sinal de cobertura fraco, dois ou mais chips e nunca desligar o celular quando dorme) e com uso de outros eletroeletrônicos. A exposição à Reni/TC foi associada aos sintomas neurológicos independente do sexo e escolaridade. Recomenda-se a adoção de medidas precaucionárias no sentido de se reduzir este tipo de exposição.
Palavras-chave: Exposição. Radiação não ionizante. Telefonia celular. Sintomas neurológicos.
FATORES ASSOCIADOS ÀS DOENÇAS TRANSMITIDAS POR ALIMENTOS EM CRIANÇAS DURANTE O CARNAVAL DE SALVADOR
Authors: Souza Andressa Silva Carneiro de , Cordeiro Nathalee Ferreira , Paiva Filho Ivan de Mattos , Santos Denise Santana Silva dos , Whitaker Maria Carolina Ortiz , Oliveira Márcia Maria Carneiro 
Published: July 2020

Doenças transmitidas por alimentos (DTA) oferecem riscos à saúde. No Brasil em 2016 foram notificadas 9.935 pessoas com DTA, reforçando a importância de conhecer os fatores associados para prevenção e planejamento da redução de incidentes. Crianças estão expostas às DTA, principalmente no carnaval. O objetivo deste artigo é descrever as características clínicas e fatores associados às DTA em crianças durante o carnaval de Salvador. Este é um estudo transversal, com análise das fichas de atendimento de crianças de 0 a 12 anos, durante o carnaval de Salvador/2016. Para análise dos dados foi utilizada a estatística descritiva, aplicou-se o teste qui-quadrado de Pearson para medidas de associação (p < 0,05). A amostra foi constituída de 127 crianças, sendo que 37,8% foram diagnosticadas com DTA. Dentre as crianças com DTA, houve o predomínio da faixa etária de 1 a 9 anos (70,8%) e sexo masculino (54,2%), folião de rua (95,8%), atendidos no circuito Osmar (52,1%), no período da tarde (31,3%). Na análise bivariada identificou-se associação de DTA com: náuseas/vômitos (p < 0,001) e dor abdominal (p = 0,001). Prevaleceu o número de crianças de 1 a 9 anos, sexo masculino e a maioria sendo folião de rua, atendidos no turno da tarde. As DTA foram associadas com náuseas/vômitos e dor abdominal.
Palavras-chave: Aglomeração. Saúde da criança. Saúde pública. Doenças transmitidas por alimentos.
PADRÕES ESPAÇO-TEMPORAIS DO SUICÍDIO NO ESTADO DE PERNAMBUCO, BRASIL
Authors: Beringuel Bárbara Marcela , Bonfim Cristine Vieira , Silva Amanda Santana 
Published: July 2020

O suicídio é considerado um problema de saúde pública mundial. Conhecer a distribuição espacial e temporal da morte autoprovocada poderá subsidiar o planejamento, implantação e avaliação de ações de prevenção. Objetivou-se descrever a ocorrência e a distribuição espaço-temporal da mortalidade por suicídio. Este é um estudo ecológico com dados do Sistema de Informações sobre Mortalidade ocorridos no estado de Pernambuco, entre 1996 e 2015. O padrão espacial foi elaborado, segundo décadas, por meio de mapas temáticos dos coeficientes médios brutos e método bayesiano empírico local. Para verificação da autocorrelação espacial e conglomerados críticos empregou-se o Índice de Moran Global e Indicador Local de Associação Espacial. Para a análise da série temporal utilizou-se o Modelo Auto Regressivo Integrado de Médias Móveis com componente sazonal (p, d, q). Registrou-se 6.229 suicídios. O coeficiente de mortalidade foi de 4,5 e 4,6/100.000 hab., na primeira e segunda década, respectivamente. Constatou-se forte autocorrelação espacial do suicídio, I = 0,6876 (1996-2005) e I = 0,68704 (2006-2015). Três agrupamentos Q1, considerados críticos, foram identificados em cada período, somando-se 25 municípios no primeiro decênio e 21 no segundo. Na análise da série temporal verificou-se a presença do componente sazonal, embora não muito acentuado. A previsão dos coeficientes de suicídio, para o período de janeiro de 2016 a dezembro de 2020, foi estável com pouca variação. A análise espacial identificou áreas críticas distanciadas da Região Metropolitana do Recife. Descrever o comportamento espacial e temporal do suicídio são aspectos importantes para adotar intervenções que busquem a redução dessa violência.
Palavras-chave: Suicídio. Análise espacial. Conglomerados espaço-temporais. Sistemas de informação em saúde. Estatísticas vitais.
Ecúmene de vivos y muertos: mala muerte y reparaciones territoriales en el Bajo Atrato
Authors: Ruiz-Serna Daniel 
Published: July 2020

En las selvas del Bajo Atrato, los combates entre guerrillas y paramilitares dejaron decenas de cuerpos sin enterrar que, transformados ahora en espíritus, han alterado las posibilidades que tienen las comunidades locales de habitar y sanar sus territorios colectivos. Sostengo que estos espíritus hacen parte de un conjunto más amplio de experiencias de dolor y sufrimiento que se inscriben en ámbitos que rebasan lo humano. Argumento que dichas experiencias constituyen un tipo de daño territorial y que su comprensión etnográfica es condición para el diseño de estrategias locales de paz y políticas regionales de reconciliación.