bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVALUATION OF IN VITRO HEPATIC TOXICITY OF LEAVES OF PTEROSPERMUM ACERIFOLIUM (L.) WILLD.
Authors: DATTA RANA , BOSE SANKHADIP , KUMAR MANDAL SUDIP 
Published: May 2020

Objective: The objective of the study was to determine the in vitro hepatic toxicity profile of methanolic extract of leaves of Pterospermum acerifolium (L.) Willd. (MEPA) using a mammalian hepatic cell line (HepG2).
Methods: To assess its in vitro hepatic toxicity, 3-(4,5-dimethylthiazol-2-yl)-2,5-2,5-diphenyltetrazolium bromide assay using MEPA at a concentration of 25 μg, 50 μg, 100 μg, 200 μg, and 300 μg was carried out. Sorafenib tosylate was used as the standard agent to assess cytotoxicity.
Results: The inhibitory concentration 50 (IC50) value for HepG2 cell lines was determined after 24 h. Thereafter the cytotoxicity study was again performed with the ½ IC50, IC50, and 2IC50 doses of MEPA. Experimentally, the IC50 was found to be 150.42 μg/ml for HepG2 using MEPA. A dose-dependent cytotoxicity and reduction in optical density were also observed with incremental MEPA administration.
Conclusion: The cytotoxic potential of MEPA was found to be much less than that of sorafenib tosylate. Thus, MEPA shows in vitro cytotoxicity in mammalian hepatic cells (HepG2) at a concentration as low as 100 μg.
BIOCONTROL POTENTIAL OF TRICHODERMA SPP. AGAINST FUSARIUM OXYSPORUM IN SOLANUM LYCOPERSICUM L.
Authors: Ramasamy Pavithra , SUNDARAM LALITHA 
Published: May 2020

Objective: The main objective of this study was to determine the effect of biocontrol Trichoderma species agent against Fusarium oxysporum in Solanum lycopersicum L.
Methods: Genus Trichoderma effective biocontrol agent against fungal, bacterial pathogen. The fungal isolates Trichoderma viride (Tr01), Trichoderma harzianum (Tr02), and F. oxysporum (Fu04) were also identified through morphological characterization observed under a light microscope (10x×40x). The isolates (Tr01, Tr02, Fu04) were confirmed through genetic DNA isolation and polymerase chain reaction analysis. After that pot culture study was conducted to test the antagonistic potential (Tr01, Tr02) and against (Fu04). Seeds of tomato (S. lycopersicum L.) were used in this experiment; treatment such as control, Tr01, Tr02, Fu04, Tr01+ Fu04, and Tr02+ Fu04 was given to the seeds sown in pots and maintained in appropriate distances.
Results: In pot culture after 45th day after inoculation of bioinoculated plant (Tr02), significantly enhances plant length, fresh weight, dry weight, chlorophyll content, nitrogen content, NPK content, and soil microbial population.
Conclusion: In this experiment, Trichoderma spp. to control plant pathogen and improve yield and quality of crop. Fungal species belonging to the genus Trichoderma act as a biological agent. Bioinoculated plant (Tr02) significantly enhances plant growth ability to with stand under nutrient deficient conditions.
TRIVALENT ION CROSS-LINKED AND ACETALATED GELLAN GUM MICROSPHERES OF GLIMEPIRIDE
Authors: DAS SUDIPTA , DEY RIMI 
Published: May 2020

Objectives: A novel formulation was developed with glimepiride loaded trivalent ion Al+3 cross-linked and acetalated gellan gum microspheres.
Methods: The glimepiride loaded microspheres were formulated using sodium alginate and gellan gum. Cross-linking agents used for the microspheres were aluminum chloride (AlCl3) and glutaraldehyde (GA). The evaluation processes of prepared microspheres were carried out by in-vitro release study, swelling index, microscopic analysis, and entrapment efficiency.
Results: All the formulations show good entrapment efficiency and the maximum entrapment 84.6% was governed by the formulation (F3) cross-linked by AlCl3 and GA and their obtained mean particle size were 12.46±3.21 μm. Release profile of the formulations revealed the sustained design of the drug, particularly this formulation (F3), releasing approximately 40% over 4 h.
Conclusions: From this experiment, it can be accustomed that F3 possesses higher standard formulation than the rest due to good release profile and entrapment efficiency. Therefore, the long term stability study is required for future development of this formulation.
DEVELOPMENT AND VALIDATION OF A GAS CHROMATOGRAPHY HEADSPACE METHOD FOR THE SIMULTANEOUS QUANTIFICATION OF SIX ORGANIC VOLATILE IMPURITIES IN SUMATRIPTAN SUCCINATEAPI AND ITS PHARMACEUTICAL DOSAGE FORMS
Authors: KISHORE J KRISHNA , RAO K PRASADA 
Published: May 2020

Objective: The main aim of this study, to develop a validated analytical method for simultaneous quantification of six organic volatile impurities (OVI) in sumatriptan succinate active pharmaceutical ingredients (API) and its pharmaceutical dosage forms by headspace (HS)-gas chromatography (GC).
Methods: The method development and its validation were performed on a Shimadzu GC-2010 GC system equipped with a flame ionization detector and Teledynetekmar HT3TM HS analyzer. The method involved a thermal gradient elution of six OVI present in sumatriptan succinate API. DB-624, 30 m×0.53 mm, 3.0 μ column is used as a stationary phase and nitrogen gas is used as a carrier gas. The flow rate was 2.8 mL/min and the flame ionization detector temperature is 260°C.
Results: The correlation coefficient (r2) was not <0.99 at the limit of quantification (LOQ) to 150%. The limit of detection obtained for methanol, acetone, isopropyl alcohol, dichloromethane, benzene, and toluene was found 18.4, 8.8, 5.5, 4.3, 0.04, and 4.2 ppm. The LOQ obtained was 55.8, 26.8, 16.6, 13.0, 0.1, and 12.6 ppm. Accuracy results were obtained from 85 to 115% for six OVI’s. Furthermore, verified precision, ruggedness, robustness, solution stability, and pharmaceutical analysis. All the results are found within the acceptable limits.
Conclusion: The method presents a simple and reliable solution for the routine quantitative analysis of organic volatile impurities present in sumatriptan succinate API.
Comparison of the efficacy and duration of desensitization of oral structures following injection of various volumes of a lidocaine-bupivacaine mixture via an infraorbital approach in dogs
Authors: Pascoe Peter J. , Chohan Amandeep S. 
Published: May 2020

Abstract

OBJECTIVE
To compare the efficacy and duration of desensitization of oral structures following injection of various volumes of lidocaine-bupivacaine via an infraorbital approach in dogs.

ANIMALS
6 healthy adult hound-type dogs.

PROCEDURES
In a randomized crossover study, each dog received 1, 2, and 3 mL of a 2% lidocaine-0.5% bupivacaine mixture (50:50 vol/vol) injected within and near the caudal aspect of the infraorbital canal with a 14-day washout period between treatments. Dogs were anesthetized, and each treatment was administered through a 22-gauge, 4.5-cm-long catheter, which was fully inserted through and then withdrawn 2 cm to the caudal aspect of the infraorbital canal. The reflex-evoked motor potential was measured for the maxillary canine tooth (MC), fourth premolar tooth (MPM4), second molar tooth (MM2), and hard palate mucosa ipsilateral to the injected treatment and for the contralateral MC (control) at predetermined times before and for 6 hours after treatment administration or until the block was no longer effective. For each oral structure, the proportion of dogs with desensitization (efficacy) and time to onset and duration of desensitization were compared among the 3 treatments (injectate volumes).

RESULTS
Treatment was not associated with efficacy, time to onset, or duration of desensitization. Regardless of treatment, MC and MPM4 were more frequently desensitized and mean durations of desensitization for MC and MPM4 were longer, compared with those for MM2 and the hard palate.

CONCLUSIONS AND CLINICAL RELEVANCE
The volume of local anesthetic used for an infraorbital nerve block had no effect on block efficacy or duration.
Effect of packed red blood cell transfusion on thromboelastographic tracings in dogs with naturally occurring anemia
Authors: Brooks Aimee C. , Cooper Edward S. , Couto C. Guillermo , Guillaumin Julien 
Published: May 2020

Abstract

OBJECTIVE
To assess the effect of packed RBC (pRBC) transfusion on thromboelastographic (TEG) tracings in dogs with naturally occurring anemia.

ANIMALS
22 clinically anemic dogs that received a pRBC transfusion.

PROCEDURES
For each dog, a blood sample was collected before and within 3 hours after completion of the pRBC transfusion for a CBC, nonactivated TEG analysis, and measurement of blood viscosity. Wilcoxon signed rank tests were used to compare CBC, viscosity, and TEG variables between pretransfusion and posttransfusion blood samples. Multivariable linear regression was used to assess the effects of pretransfusion-posttransfusion changes in Hct, WBC count, and platelet count on changes in TEG variables.

RESULTS
Median posttransfusion Hct (21%; range, 13% to 34%) was significantly greater than the median pretransfusion Hct (12.5%; range, 7% to 29%). Packed RBC transfusion was associated with a median increase in Hct of 6.2% (range, 1.2% to 13%). Maximum amplitude significantly decreased from 74.9 to 73.8 mm and clot strength significantly decreased from 14,906 to 14,119 dynes/s after pRBC transfusion. Blood viscosity significantly increased, whereas platelet and WBC counts significantly decreased after transfusion. Multivariable linear regression revealed that pretransfusion-posttransfusion changes in Hct, WBC count, and platelet count were not associated with changes in TEG variables.

CONCLUSIONS AND CLINICAL RELEVANCE
Results indicated that pRBC transfusion had only small effects on the TEG tracings of hemodynamically stable dogs. Therefore, large changes in TEG tracings following pRBC transfusion are unlikely to be the result of the transfusion and should be investigated further.
AYAM LEHER GUNDUL: SEJARAH, KARAKTERISTIK, DAN KONSERVASI
Authors: T. Kostaman 
Published: May 2020

Ayam leher gundul adalah ayam asli/lokal Indonesia yang belum banyak diketahui informasinya dalam halsejarah, potensi, dan karakteristik; sehingga belum dimanfaatkan secara optimal. Ciri yang paling menonjoldari ayam leher gundul adalah tidak mempunyai bulu dibagian lehernya. Untuk mempertahankannya, metode konservasi yang telah dilakukan oleh Balai Penelitian Ternak (Balitnak) adalah dengan memelihara ternak hidup, akan tetapi dengan keterbatasan sarana dan prasarana tidak dapat dilanjutkan. Data performan ayam leher gundul yang dipelihara di Balitnak sudah terkumpul dan ditabulasi. Alternatif konservasi yang dilakukan oleh Balitnak untuk mempertahankan plasma nutfah ayam leher gundul adalah berupa primordial germ cell (PGC) yang dibekukan pada suhu -196 oC yang sewaktu-waktu dibutuhkan dapat ditransfer ke embrio resipien. Sumber PGC yang di koleksi adalah dari darah dan gonad embrio. Berdasarkan potensi yang dimilikinya, ayam leher gundul memiliki performan yang baik, sehingga dapat dimanfaatkan sebagai ayam lokal penghasil daging dan telur. Tulisan ini diharapkan dapat bermanfaat sebagai data pendukung bagi upaya pelestarian dan pengembangan ayam-ayam lokal yang ada di Indonesia, khususnya ayam leher gundul dan umumnya ayam-ayam lokal Indonesia lainnya.
PENAMPILAN PEDET SAPI BALI HASIL INSEMINASI BUATAN DARI PEJANTAN BERBEDA
Authors: M. Dewantari , Oka A. A. 
Published: May 2020

Inseminasi Buatan (IB) adalah salah satu teknologi reproduksi yang telah berhasil meningkatkan mutu genetik ternak, dan dalam waktu pendek dapat menghasilkan anak dengan kualitas baik dalam jumlah yang besar dengan memanfaatkan pejantan unggul. Penelitian ini bertujuan untuk mengetahui penampilan pedet sapi bali hasil inseminasi buatan dari pejantan yang berbeda. Penelitian menggunakan data primer dan sekunder. Data sekunder berupa catatan berat lahir sapi hasil inseminasi buatan dan data primer merupakan pengukuran berat dan dimensi tubuh anak-anak sapi hasil inseminasi buatan dari pejantan berbeda. Statistik deskriptif digunakan untuk membantu memaparkan keadaan yang sebenarnya dari potensi produksi pejantan yang dipakai sebagai sumber semen sehingga diperoleh data dasar tentang potensi produksi. Hasil penelitian menunjukkan bahwa tidak ada perbedaan bobot lahir pedet sapi dari pejantan berbeda, demikian juga terhadap bobot dan dimensi tubuh pedet sapi pra sapih hasil inseminasi buatan dari pejantan berbeda. Kesimpulan dari penelitian ini bahwa pejantan yang digunakan dalam penelitian ini mempunyai kualitas yang sama.
Features of ambulatory and stationary treatment of patients with endometriosis
Authors: Oboskalova Tat’iana A. , Gluhov Evgenii Yu. , Astryuhina Irina I. 
Published: May 2020

Background. Most common clinical manifestations of endometriosis (N80) include pelvic pain and infertility, while adenomyosis is associated with abnormal uterine bleeding. At present, approach to the treatment of endometriosis has been revised towards shifting surgery to the second-line therapy; medications are considered as the first-line therapy: gonadotropin releasing hormone agonists, progestogens, aromatase inhibitors.
Aim. Comparison of clinical and anamnestic characteristics and therapeutic procedures in women who were treated on an outpatient basis and those who were hospitalized and underwent surgical intervention.
Materials and methods. Clinical-anamnestic and morphological characteristics were studied in two groups of women: 1st group (n=27) received drug therapy, 2nd group (n=28) underwent surgical intervention.
Results and discussion. In the 1st group, 25.9% of patients received microdosed combined oral contraceptives which contain dienogest as a progestogen component, 44.4% of patients received monotherapy with dienogest, and 22.2% of patients received dydrogesterone in a prolonged mode. In the 2nd group, 39 foci of endometriosis, isolated and in a combination of various loci, were revealed during surgery, of which 30.8% were ovarian cysts, 10.2% were foci on the sacro-uterine ligaments, 23.1% were on the pelvis peritoneum. Surgical approach was determined by the urgency of intervention, an expect localization of endometriosis foci, a comorbidity of endometriosis with another pathology of the internal genitalia, 82.1% of surgery were performed by laparoscopic approach.
Conclusions. The choice of treatment method depends on the severity of symptoms, the severity of endometriosis, the woman age and her reproductive intentions. When choosing a surgical treatment, one should be guided not only by the need for the most radical removal of endometriosis foci, but also should consider a surgical approach to minimize discomfort and provide a good quality of life after surgery. A three-stage model for the management of patients with endometriosis is proposed, which includes an assessment of treatment effectiveness and the need to develop a rehabilitation program.
DESCRIBING KITAB PERUKUNAN BESAR MELAYU BY ABDUL RASYID BANJAR FROM THE LETTER OF ALPHABET CONCEPT TO SYNTHESIS CONSTRUCTION
Authors: MZ Zulfiana Amaliana 
Published: May 2020

As the spread of Islam in the archipelago, a manuscript found in 19th century AD entitled Perukunan Besar Melayu by Abdul Rasyid Banjar. It was about Fiqh which described using Bahasa and written in Arab-Melayu. So, it used as an object of research that categorized as a qualitative research with a philological descriptive approach. This study aims to describe 1) transliterated of the manuscript to obtain complete and clear editing, 2) compliances of spelled and punctuated, and 3) distribution of syntax. To achieve the research objectives, data analysis carried out using the philological work procedure techniques and comparative analysis. So, the result of this research is 1) transliterated of Arab-Melayu alphabet into Latin alphabet, 2) reconstruction of spelled and punctuated, and 3) syntactic reconstruction
KESESUAIAN DAERAH PENANGKAPAN RAJUNGAN (Portunus pelagicus) MENGGUNAKAN ANALISIS SPASIAL PARAMETER LINGKUNGAN DAN HASIL TANGKAPAN DI PULAU LANCANG
Authors: Rahimah Insaniah , Siregar Vincentius , Agus Syamsul 
Published: May 2020

The blue swimming crab in the waters of Lancang Island is indicated as being overfished. Hence, the major challenge is managing its utilization in a proper manner. The purpose of this study is to explore the water's characteristics which is suitable for blue swimming crab fishing. Accordingly, the potential fishing ground around Lancang Island waters can be mapped spatially as an initial effort for species preservation. Geospatial analysis was applied to assess the physical parameters of the existing habitat. The results show that parameters such as MPT, TDS, brightness, phosphate, nitrate, depth and substrate types were remarkably suitable to support the growth of blue swimming crabs. Meanwhile, parameters such as salinity, DO, and temperature show lower quality which implied that the habitat is less suitable. However, the result of weighting and reclassification conclude that Lancang island waters is a decent habitat for blue swimming crab. Catch data show that 40% blue swimming crabs have small carapace size (7-11.83 cm) which is undersized and prohibited by law. Furthermore, about 68% of catch are quite light (30-147 gr) and the sex ratio of males to females was 1:2. It was also revealed that approximately 35% of female species were carrying eggs (BEF/barried female).
Keywords: geospatial, fishing ground, suitability, Lancang Island, blue swimming crab.
Guest Editorial Introduction 客座主编介绍
Authors: Tian Mei , Lu Genshu 
Published: May 2020

In this special issue editorial, we firstly discuss the sharp contrast between the rich English literature on Chinese students overseas, and the limited studies published in international journals on international students in China. We then introduce the rapid expansion of international student enrolment in China in recent ten years, pointing to the significance and urgency to deepen our understandings of these students’ experiences. The editorial ends with an introduction to the contents of the articles included in the special issue. We hope that this issue on international students in China will motivate Chinese-speaking researchers in and outside China to contribute to this important research area. 本文首先讨论了海外针对中国留学生经历的究热情，指出目前发表在国际期刊上的围绕来华留学生经历的研究还十分有限，二者形成了鲜明的对比。随后介绍了来华留学生近年来的发展与增长趋势，反映出深入研究来华留学生经历、来华留学生教育的重要性与紧迫性。最后介绍了收录在本辑特刊中的文章内容。我们希望可以以《国际学生杂志》中文特刊为契机，鼓励更多的中国本土与海外学者贡献于这一重要的研究领域。
Study on RBC Count and Hb level between Bangladeshi and Kashmiri Medical Students of Khwaja Yunus Ali Medical College
Authors: Yasmin Ayesha , Alo Kamrunnahar , Sultana Sabera , Yesmin Laila 
Published: May 2020

Background: Among the different blood parameters the total RBC count and blood hemoglobin level is important for the diagnosis of anemia. The results vary in different nations for environmental conditions and different dietary habits.
Objectives: This study was to observe the total RBC count and blood Hb level in between the Bangladeshi and Kashmiri students of same age group. Dietary chart was also studied in between the two nationalities of students to observe any alteration of the result or not.
Materials and Methods: This random study was done in Khwaja Yunus Ali Medical College, Sirajganj, Enayetpur on September, 2019. Total 200 students were included with specific age range, sex and diet history. The students were divided as 100 male and 100 female students. Total RBC count was estimated by fluid dilution (Dacie's fluid) method and Hb level was estimated by Sahli's acid hematin method.
Results: Among 200 students, 94% Bangladeshi male and 98% Bangladeshi female and among Kashmiri's 96% male and 94% female students were in age between 19 to 21 years. Total RBC count>5million/cumm of blood was found in 24% Kashmiri and 08% Bangladeshi male students. Total RBC count in between 4M/cumm to 5M/cumm was present in 84% and 94% of Bangladeshi male and female students respectively and among 76% Kashmiri male and 90% Kashmiri female students. Hemoglobin level >15gm/dl was found among 54% Kashmiri and 10% Bangladeshi male students. It was alo observed that Kashmiri students were more habituated to protein rich diet than the Bangladeshi students.
Conclusion: Present study revealed that environment and diet habit has an impact on alteration of total RBC count and blood Hb level.
KYAMC Journal Vol. 11, No.-1, April 2020, Page 32-35
Budd Chiari Syndrome in Children
Authors: Khadga Mukesh , Hasan Mahmudul , Rahman AZM Raihanur , Ahamed Nazmul , Md Benzamin - , Rahman Mohammad Ahmadur , Karim ASM Bazlul 
Published: May 2020

Budd-Chiari syndrome (BCS) is a rare disorder presenting with hepatic venous outflow obstruction from the level of the hepatic veins to the junction of the inferior vena cava (IVC) with the right atrium. It is rare in infants and children so, delay in diagnosis or misdiagnoses are very commonly seen. It results from either primary or secondary cause. Hypercoagulable state can be identified in majority of the cases. The clinical presentations may vary from asymptomatic to fulminant liver failure. A high index of suspicion and imaging findings may help in early diagnosis of this condition.Doppler ultrasonography can be the initial diagnostic investigation of choice.The treatment options include medical therapy along with surgical measures including liver transplantation for end-stage liver disease.
KYAMC Journal Vol. 11, No.-1, April 2020, Page 46-49
Film stars in the perspective of performance studies: play, liminality and alteration in Chinese Cinema
Authors: Zhang Yingjin 
Published: May 2020

Star studies sees film stars as “structured polysemy” and anticipates a salient system of meaning for us to decode and appreciate. Performance theory treats meaning as “conjunctural” rather than “structured” and privileges improvisation and juxtaposition. Approaching star studies through performance theory helps explore a wealth of filmic techniques and performative tactics. This article focuses on Tony Leung Chiu-Wai’s “self-effacing” performance of repetition and examines special cases of play and liminality as well presence and absence in In the Mood for Love (Wong Kar-Wai, 2000) and Lust Caution(Ang Lee, 2007). These cases challenge our conventional habit of thought and cognition and reveal the unacknowledged potential of artistic alternative and alteration vis-à-vis history and reality. This study of Tony Leung’s performance directs attention beyond action stars to romantic male roles in Chinese films.
‘Una diva non come le altre’: Le streghe and the paradoxical stardom of Silvana Mangano
Authors: Hunt Leon 
Published: May 2020

Silvana Mangano’s stardom is marked by a series of paradoxes - a ‘reluctant’ diva who shed the voluptuous body that made her world famous, a star whose career was shaped first by a powerful film producer (husband Dino De Laurentiis) and then by two arthouse auteurs (Pasolini and Visconti). This paper explores these paradoxes particularly through the episode film Le Streghe/The Witches (1967), often seen as the transition from her ‘De Laurentiis career’ to her ‘Pasolini-Visconti career’. Unusual as an actual star vehicle for Mangano, the film casts her as a glamorous movie diva not unlike herself, a bored housewife (married to Clint Eastwood), a fiery ‘Siciliana’, a spoilt society girl and a holy mute. It thus invites particular consideration of Mangano as both actress and problematic star.
After Life – Expressions of Mourning in Elizabeth von Arnim and Katherine Mansfield
Authors: Römhild Juliane 
Published: May 2020

Like many women, Katherine Mansfield and Elizabeth von Arnim lost members of their immediate family in the Great War, and both writers worked through their loss in writing. Although their work is stylistically and thematically different, the expressions of grief in their work shares certain characteristics with other (post-)war writing. This article examines the literary responses to personal to loss in von Arnim’s novels Christine and In the Mountains, as well as Mansfield’s New Zealand stories and “The Fly” with the help of their private diaries and letters.