bluuebunny/crossref_metadata_2025_split huggingface dataset:
TESTE RÁPIDO MOLECULAR PARA TUBERCULOSE: DA COLETA AO INÍCIO DO TRATAMENTO
Authors: Rodrigues Ivaneide Leal Ataíde , Nogueira Laura Maria Vidal , Oliveira Livia Felix de , Silva Adriana Leal Gomes da , Monteiro Nicole Jucá , Távora Marune Melo 
Published: September 2020

Objetivo: identificar o tempo decorrido entre a coleta do material para teste rápido molecular e o início do tratamento para tuberculose em unidades que encaminharam amostras para processamento em Unidades centralizadoras.Método: estudo epidemiológico analítico desenvolvido em duas Unidades Básicas de Saúde em Belém-Pará. Foram coletados dados referentes a 296 casos novos com confirmação laboratorial, diagnosticados de dezembro de 2014 a dezembro de 2015. Na análise, utilizou-se o Teste U de Mann-Whitney, p-valor ≤ 0,05 para a correlação entre as variáveis.Resultados: não houve diferença estatisticamente significativa no tempo de liberação dos resultados de exames em Unidades Centralizadoras e Unidades que encaminharam exames para processamento. Quanto ao início do tratamento, houve diferença no tempo entre as unidades centralizadoras e as de abrangência.Conclusão: a centralização do processamento do Teste Rápido Molecular não interfere no tempo para diagnóstico e tratamento da tuberculose, mesmo com o encaminhamento das amostras entre os serviços.
INDICADORES DE QUALIDADE EM CENTRO CIRÚRGICO ESPECIALIZADO EM DERMATOLOGIA
Authors: Amaral Juliana Aparecida Baldo , Spiri Wilza Carla , Assis Márcio Antônio de , Guimarães Heloísa Cristina Quatrini Carvalho Passos , Lima Silvana Andrea Molina 
Published: September 2020

Objetivo: identificar e caracterizar os indicadores de qualidade mais frequentes utilizados em um Centro Cirúrgico público especializado em dermatologia.Método: estudo transversal seccional, pelo qual fez-se um levantamento, com registros diários, dos mais frequentes indicadores entre os 20 existentes na unidade, no período de agosto de 2015a julho de 2016. Considerou-se: médias, medianas, valores mínimos/máximos, desvios padrões, frequências simples e percentuais. O valor de p<0,05 foi considerado como nível de signfiicância.Resultados: das 595 cirurgias eletivas, destacaram-se as ambulatoriais (87,9%), as dermatológicas (81,3%), em pacientes do sexo masculino (52,6%), com média de 54,9 anos. Os cinco indicadores mais frequentes foram: cirurgias suspensas (17,6%); registros de enfermagem incompletos (14%); absenteísmo (6,5%); infecção em sítio cirúrgico em cirurgias limpas (2,7%) e acidentes de trabalho (2,2%).Conclusões: a identificação e a caracterização dos indicadores de qualidade proporcionaram visibilidade aos processos locais, viabilizando a tomada de decisões e o aperfeiçoamento dos serviços prestados.
DIREITOS HUMANOS DAS MULHERES NO PARTO FRENTE À PANDEMIA DE COVID-19: O QUEFAZER DA ENFERMAGEM OBSTÉTRICA
Authors: Souza Kleyde Ventura de , Schneck Søndre , Pena Érica Dumont , Duarte Elysângela Dittz , Alves Valdecyr Herdy 
Published: September 2020

Objetivo: esta comunicação tem por objetivo provocar a reflexão de enfermeiras(os) obstétricas(os) a seguir na luta pela garantia de direitos das mulheres e de seus bebês, em meio à pandemia de COVID-19.Desenvolvimento: chama a atenção a violação dos Direitos Humanos das mulheres, seus filhos e de enfermeiras obstétricas e obstetrizes, principalmente pelo impacto da pandemia. Endossa a Declaração da International Confederation of the Midwives intitulada “Os direitos das mulheres no parto devem ser mantidos durante a pandemia”, e evoca a Enfermagem Obstétrica a um quefazer, solidário e pautado pela justiça social, construído e anunciado pelos corpos e vozes daquelas(es) que cuidam e são cuidadas(os).Considerações Finais: sinalizamos o compromisso político-social com a democracia enquanto processo que legitima a cidadania num campo especial de interesse: a vida e a saúde das mulheres, a partir do direito constitucional e dos desafios éticos que nos convoca a pandemia.
RECOMENDAÇÕES PARA O CUIDADO À CRIANÇA FRENTE AO NOVO CORONAVÍRUS
Authors: Pacheco Sandra Teixeira de Araújo , Nunes Michelle Darezzo Rodrigues , Victória Juliana Zambrano , Xavier Welker Da Silva , Silva Jaciane Alexandre da , Costa Cícero Ivan Alcantara 
Published: September 2020

Objetivo: identificar na literatura nacional e internacional as recomendações para o cuidado de crianças frente ao novo coronavírus.Método: revisão integrativa, realizada no mês de abril de 2020, nas bases de dados Web of Science, CINAHL, BDENF, IBECS, LILACS, MEDLINE. Foram incluídos artigos de recomendação publicados em 2020. Excluíram-se estudos clínicos, sobre outras temáticas ou populações.Resultados: a amostra foi constituída por 10 artigos, agrupados em três categorias derecomendações, que tratam: do cuidado a crianças com câncer; da busca pela diminuição dos malefícios biopsicossociais do confinamento; e das possibilidades de diagnóstico e tratamento.Conclusão: as recomendações destacadas não se esgotam, mas representam um direcionamento para familiares/cuidadores e profissionais de saúde diante da grave situação. Para a enfermagem, conhecer as recomendações atuais sobre os cuidados a criança frente à COVID-19 possibilita a realização de ações para a promoção do cuidado de qualidade e seguro à criança.
Coloring of food by the use of natural color extracted by beetroot (Beta Vulgaris), betalain pigment
Authors: Chaudhary Sonika 
Published: September 2020

Color is one of the most important quality attribute in the food products. The purpose of adding color in the foods is to make them attractive, to influence the consumer to buy the product and also to improve the quality of the food product. At the present time the demand of natural color is increased in worldwide due to the awareness of people on therapeutic medicinal properties and their benefits in the place of synthetic colors. Synthetic colors are harmful for health and show toxicity in food products. Natural color are those pigments which is derived from naturally sources such as plants, insects, animals, vegetables and fruits etc. among all these natural dyes, plant based pigments have medicinal values so are mostly preferred. Today the food industry are mostly preferred the use of natural coloring pigment in their food products because the generation of this time is very possessive to their health and preferred the food product which is made from the use of natural color. The present study is based on the use of natural colors in food product in the place of synthetic color. The natural color was extracted from beetroot (Beta Vulgaris) named as betalain pigment. Betalain pigment is rich in antioxidant property, vitamin A and C and also a good source of iron, calcium etc. In this experiment the use of the natural color in the preparation of cookies.Keywords: natural food color, dyes, extraction, pigment, beetroot, betalain, cookies.
On Generalized Pentanacci and Gaussian Generalized Pentanacci Numbers
Authors: Soykan Yüksel 
Published: September 2020

In this paper, we present Binet’s formulas, generating functions, and the summation formulas for generalized Pentanacci numbers, and as special cases, we investigate Pentanacci and PentanacciLucas numbers with their properties. Also, we define Gaussian generalized Pentanacci numbers and as special cases, we investigate Gaussian Pentanacci and Gaussian Pentanacci-Lucas numbers with their properties. Moreover, we give some identities for these numbers. Furthermore, we present matrix formulations of generalized Pentanacci numbers and Gaussian generalized Pentanacci numbers.
Pesticide Residues and Their Degradation Products as Influenced by Acidity and Organic Matter in Kura Irrigation Farmland Soils
Authors: Olukanni C. O. , Audu A. A. , Waziri M. 
Published: September 2020

The aim of this research is to determine the insecticide and herbicide residues and their degradation products in Kura irrigation farmland soils. The analyses were carried out during the planting (before harvest) and after the harvesting periods. The insecticide residue analyses were undertaken using Gas chromatography-mass spectrometry (GC/MS) after extraction with a mixture of n-hexane and acetone (1:1) in a soxhlet extractor. The pH levels of the soil samples and the soil organic matter were also determined using standard analytical methods. The acidity and organic matter content of most of the soil samples increased slightly after harvest. The compounds detected as residues include 1-octadecene, 9-heptadecanone, (E)-3-eicosene, (Z)-5-nonadecene, heptadecane, 1-docosene, 1-nonadecene and 1-eicosene. Out of these residues, 1-octadecene and (E)-3-eicosene were detected during planting and after the harvesting periods, showing that they are the most persistent of the residues in the soil samples. The residues detected before harvest were totally different from the residues detected after harvest. This shows that the pesticides, after some time, degraded in the soil into completely different compounds and the total residues were detected in high percentages.
Linear Coassembly of Upconversion and Perovskite Nanoparticles: Sensitized Upconversion Emission of Perovskites by Lanthanide‐Doped Nanoparticles
Authors: Estebanez Nestor , Cortés‐Villena Alejandro , Ferrera‐González Juan , González‐Béjar María , Galian Raquel E. , González‐Carrero Soranyel , Pérez‐Prieto Julia 
Published: September 2020

AbstractSensitized emission of lead halide perovskite nanoparticles (LHPNPs) can be achieved by near‐infrared (NIR) excitation of nearby lanthanide‐doped upconversion nanoparticles (UCNPs) by using a low‐cost diode laser. Here, the first preparation of linear assemblies of core and core–shell NPs, as well as linear coassemblies of LHPNPs and UCNPs, within an open peapod‐like lead sulfate shell are reported. UCNPs with a NaYF4 matrix doped with ytterbium and thulium or erbium, and with an inert shell of NaYF4 in the case of core‐shell, and all‐inorganic CsPbX3 NPs (X = halide) are chosen for these studies. Interestingly, the lead sulfate shell enhances the luminescence of the core/core– shell UCNPs in the polymers by ≈20‐fold and it also plays a role in the efficiency of the sensitized emission of the LHPNPs under NIR excitation of the UCNP‐LHPNP copolymers, as well as in the chemical stability of the LHPNPs in contact with water. The (co)polymers are prepared as colloids and deposited as solid films on a glass substrate. The lifetime of the sensitized LHP emission and the efficiency of the process wholly depends on the irradiance and on the sample state. These copolymers are promising candidates for the manufacture of photonic devices.
Obstructive sleep apnea in adults with Down syndrome
Authors: Landete Pedro , Soriano Joan B. , Aldave Beatriz , Zamora Enrique , Acosta Carmen , Erro Marta , López Riolobos Cristina , Ramos M. Inmaculata , Moldenhauer Fernando , Ancochea Julio 
Published: September 2020

AbstractPatients with Down syndrome (DS) often have a high occurrence of obstructive sleep apnea‐hypopnea (OSA) syndrome. We studied a large cohort of adults with DS attended due to clinical suspicion of OSA. A standardized questionnaire and full medical assessment were conducted, including a sleep study. One hundred and fifty‐seven DS individuals were studied, with a mean ± SD age of 36 ± 10 years, 40.7% women, BMI 29.4 ± 5.6 kg/m2. The main clinical symptom was daytime sleepiness (64.9%). A sleep study was conducted in 114 patients. All 114 DS patients were diagnosed with OSA, with a predominance of obstructive and hypopnea events, (apnea‐hypopnoea index, AHI, 35.0 ± 26.6), with an oxygen desaturation index of 32.9, and a Tc90% of 24.7%. Continuous positive airway pressure (CPAP) treatment was implemented in 75 (65.8%) of subjects. Tolerance was considered good in 75% of them, with a high compliance of 79.2% >4 hr/day (mean 7.1 hr/day), resulting in a symptomatic improvement in 58.7% of them. Obstructive sleep apnea is frequently confirmed in patients with DS when it clinically suspected. Treatment with CPAP in DS is feasible, and with higher adherence than in adults with normal cognitive functioning.
Direct β‐ and γ‐C(sp3)−H Alkynylation of Free Carboxylic Acids**
Authors: Ghiringhelli Francesca , Uttry Alexander , Ghosh Kiron Kumar , van Gemmeren Manuel 
Published: September 2020

AbstractIn this study we report the identification of a novel class of ligands for palladium‐catalyzed C(sp3)−H activation that enables the direct alkynylation of free carboxylic acid substrates. In contrast to previous synthetic methods, no introduction/removal of an exogenous directing group is required. A broad scope of acids including both α‐quaternary and challenging α‐non‐quaternary can be used as substrates. Additionally, the alkynylation in the distal γ‐position is reported. Finally, this study encompasses preliminary findings on an enantioselective variant of the title transformation as well as synthetic applications of the products obtained.
Encapsulation of Unsaponifiable Matter of Rice Bran Oil Bychitosan and Lepidium perfoliatum Seed Gum: Characterization and Antioxidant Activity
Authors: Jamshidi Mahboobeh , Kenari Reza Esmaeilzadeh , Motamedzadegan Ali , Biparva Pourya 
Published: September 2020

AbstractThe unsaponifiable matter (USM) of Tarom and Fajr rice bran oil were encapsulated with chitosan (CS) and Lepidium perfoliatum seed gum (LPSG) and physicochemical and structural properties, the total phenolic content and the antioxidant activity of particles were assessed. The results indicated that particles had a mean size of 145.5–232.7 nm with a narrow size distribution. Besides, theencapsulation efficiency of encapsulated powdersranged from 74.36 to 83.09%.Scanning electron microscopy (SEM) images showed the formation of the spherical‐shaped and aggregated particles. Differential scanning calorimetry (DSC) thermograms and Fourier transform infrared spectroscopy analyses confirmed the successful encapsulation of USM. The encapsulated powdersshowed higher total phenolic content than free USM, while presenting desirable antioxidant activity. In addition, the samples coated by LPSG presented better physicochemical properties than those coated by CS. Finally, our results suggested that encapsulated powders could have a promising application in food systems.
Implementation of p16/Ki67 dual stain cytology in a Danish routine screening laboratory: Importance of adequate training and experience
Authors: Hammer Anne , Gustafson Line W. , Christensen Pia N. , Brøndum Rikke , Andersen Berit , Andersen Rikke H. , Tranberg Mette 
Published: September 2020

AbstractBackgroundImmunocytochemical staining with p16/Ki67 has been suggested as a promising triage biomarker in cervical cancer screening. As dual staining is a subjective method, proper training may be required to ensure safe implementation in routine laboratories and reduce risk of misclassification. We determined concordance between novice evaluators and an expert, stratified by number of slides reviewed at three reading points.MethodsThe study was conducted at the Department of Pathology, Randers, Denmark. Women were eligible if they were aged ≥45, had been enrolled in one of two ongoing clinical studies, and had a dual stain slide available. Dual staining was performed using the CINtec plus assay. Slides were randomly selected from three reading points at which novice evaluators had reviewed <30, ~300, and ≥500 dual stain slides respectively. Level of concordance was estimated using Cohen's Kappa, κ.ResultsOf 600 eligible slides, 50 slides were selected for review as recommended by the manufacturer. Median age was 68 years (range: 58‐74). Overall concordance was good (κ = 0.68, 95% confidence interval [CI]: 0.60‐0.76), with an overall agreement of 84% (95% CI: 70.9%‐92.8%). Concordance improved with increasing number of slides reviewed at a given reading point, from a moderate concordance (κ = 0.47, 95% CI: 0.05‐0.90) after reviewing <30 slides to a good concordance (κ = 0.66, 95% CI: 0.20‐0.88) and a very good concordance (κ = 0.88, 95% CI: 0.66‐1.00) after reviewing ~300 and ≥500 slides, respectively.ConclusionsWhen interpreting dual stain slides from older women, concordance increased slightly as novice evaluators received more training and experience. Although further evaluation is warranted, these findings indicate that a significant amount of training and experience of novice evaluators may be needed to ensure accurate dual stain interpretation in this age group. Future studies should accurately describe training and experience of evaluators to enable a better comparison of concordance and diagnostic accuracy across studies.Trial registrationNCT04114968 and NCT04298957.
Ultrasound‐guided Erector Spinae Plane Block (US‐ESPB)—Anesthetic block: Case report
Authors: Coviello Antonio , Vargas Maria , Castellano Gaetano , Maresca Alfredo , Servillo Giuseppe 
Published: September 2020

AbstractThe Ultrasound‐guided Erector Spinae Plane Block (US‐ESPB), used as an anesthesiological block, could represent a safe and effective alternative for thoracic wall surgery especially in fragile, obese patients and those with respiratory and/or hemodynamic problems.
Racial disparities in mortality for patients with prostate cancer after radical prostatectomy
Authors: Wen Wanqing , Luckenbaugh Amy N. , Bayley Christina E. , Penson David F. , Shu Xiao‐Ou 
Published: September 2020

BackgroundAlthough racial disparities in prostate cancer survival are well documented, the relative importance of contributing factors remains unclear. Few studies have examined the disparity between Whites and Hispanics or between Whites and Asian Americans and Pacific Islanders (AAPIs).MethodsUsing data from the National Cancer Database for 526,690 patients with prostate cancer who underwent radical prostatectomy between 2004 and 2014, this study systematically evaluated the impact of clinical characteristics and factors related to access to care on survival by race. Included in the analysis were 432,640 White patients (82.1%), 63,602 Black patients (12.1%), 8990 AAPI patients (1.7%), and 21,458 Hispanic patients (4.1%). Multivariable Cox proportional hazards models were used to estimate hazard ratios and 95% confidence intervals to measure racial survival disparities. Inverse probability weighting was used to adjust for imbalances of prognostic factors.ResultsWhen adjustments were made for age and year of diagnosis only, Blacks had 51% higher mortality, AAPIs had 22% lower mortality, and Hispanics had 6% lower mortality than Whites. Overall, with adjustments for all clinical factors and nonclinical factors, the Black‐White survival disparity narrowed to 20%, whereas the AAPI‐White disparity increased to 35%. Among the controlled‐for factors, education, median household income, and insurance status contributed the most to the racial disparity.ConclusionsThe overall survival disparity among men undergoing radical prostatectomy was significantly decreased, but not eliminated, for Blacks and significantly increased for AAPIs in comparison with Whites after adjustments for a number of clinical factors and factors related to access to care.
All‐inorganic Sn‐based Perovskite Solar Cells: Status, Challenges, and Perspectives
Authors: Liu Yanghua , Gao Weiyin , Ran Chenxin , Dong He , Sun Nan , Ran Xueqin , Xia Yingdong , Song Lin , Chen Yonghua , Huang Wei 
Published: September 2020

AbstractRecently, the power conversion efficiency (PCE) of perovskite solar cells (PSC) based on organic‐inorganic hybrid Pb halide perovskites has reached 25.2 %. However, the toxicity of Pb has still been a main concern for the large‐scale commercialization of Pb‐based PSCs. Efforts have been made during the past few years to seek eco‐friendly Pb‐free perovskites, and it is a growing consensus that Sn is the best choice as Pb alternative over any other Pb‐free metal elements. Among Sn‐based perovskites, all‐inorganic cells are promising candidates for PSCs owing to their more suitable bandgap, better stability, and higher charge mobility compared to the organic‐inorganic hybrid counterparts. However, the poor phase stability of all‐inorganic Sn‐based perovskites (AISPs) and low PCE of their PSCs are most challenging in the field at present. Herein, recent developments on PSCs based on AISPs, including CsSnX3 and Cs2SnX6 (X=Br, I), are comprehensively reviewed. Primarily, the intrinsic characteristics of the two AISPs are overviewed, including crystallographic property, band structure, charge carrier property, and defect property. Sequentially, state‐of‐the‐art progress, regarding the photovoltaic application of AISPs as light absorber, is summarized. At last, current challenges and future opportunities of AISP‐based PSCs are also discussed.
Association between dopamine beta‐hydroxylase polymorphism and attention function in suicide attempters with chronic schizophrenia
Authors: Hui Li , Hu Wei Ming , Zhu Zhen Hua , Gao Song Tian , Han Mei , Fan Yu , Tian Qing , Yin Xu Yuan , Yuan Ying , Jiang Cai Xia , Yin Guang Zhong , Jia Qiu Fang , Zhang Xiang Yang 
Published: September 2020

AbstractBackgroundPatients with schizophrenia are at a higher risk for suicide compared with the general population. Dopamine beta‐hydroxylase (DβH) plays a key role in the conversion of dopamine to norepinephrine, which is related to suicidal behavior and cognitive regulation.ObjectiveTo examine whether there is the effect of DβH 5′‐insertion/deletion (Ins/Del) polymorphism on cognitive performance in suicide attempters with chronic schizophrenia.MethodsThis polymorphism was detected in 114 suicide attempters and 617 non‐suicide attempters with chronic schizophrenia. Cognitive performance was assessed by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).ResultsThe allelic and genotypic frequencies of this polymorphism between two groups did not differ after controlling for covariates (both, p > .05). There were no differences in RBANS scores between two groups after adjusting for covariates (all, p > .05). However, based on the genotype grouping in suicide attempters and non‐attempters, the attention score significantly differed after adjusting for covariates (both, p < .05). Further analysis indicated that this polymorphism was associated with attention score in suicide attempters (p < .05), but not in non‐suicide attempters (p > .05).ConclusionsDβH 5′‐Ins/Del polymorphism was not a risk locus of suicide attempters, but it was implicated in attention regulation in suicide attempters with chronic schizophrenia.
Fatal COVID‐19 infection in a patient with long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency: A case report
Authors: Wongkittichote Parith , Watson James R. , Leonard Jennifer M. , Toolan Elizabeth R. , Dickson Patricia I. , Grange Dorothy K. 
Published: September 2020

AbstractLong‐chain fatty‐acyl CoA dehydrogenase deficiency (LCHADD) is an inborn error of long chain fatty acid oxidation with various features including hypoketotic hypoglycemia, recurrent rhabdomyolysis, pigmentary retinopathy, peripheral neuropathy, cardiomyopathy, and arrhythmias. Various stresses trigger metabolic decompensation. Coronavirus disease 2019 (COVID‐19) is a pandemic caused by the RNA virus SARS‐CoV‐2 with diverse presentations ranging from respiratory symptoms to myocarditis. We report a case of a patient with LCHADD who initially presented with typical metabolic decompensation symptoms including nausea, vomiting, and rhabdomyolysis in addition to mild cough, and was found to have COVID‐19. She developed acute respiratory failure and refractory hypotension from severe cardiomyopathy which progressed to multiple organ failure and death. Our case illustrates the need for close monitoring of cardiac function in patients with a long‐chain fatty acid oxidation disorder.