bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fluorescence in situ hybridization on Peripheral blood for Chronic Myeloid Leukaemia - Rapid and reliable method
Authors: A. Meenakshi , D. Prashanth Shetty , N. Suchetha Kumari , Mathias Michelle , Kumar Karuna Ramesh , Shetty Jayaprakash 
Published: April 2020

AbstractPhiladelphia chromosome (Ph) is found in more than 95% of Chronic Myeloid Leukaemia (CML) patients arising from the reciprocal translocation of chromosomes 9 and 22 which results in the formation of chimeric fusion gene BCR-ABL. This paved the path for targeted gene therapy in CML and thus plays a pivotal role in diagnosis and prognosis. Fluorescence in situ hybridization (FISH) is a rapid and reliable technique in molecular cytogenetics to detect BCR-ABL fusion signal in both interphase and metaphase spreads of bone marrow sample. Peripheral blood white cells as a surrogate for bone marrow have been suggested by a few studies.The objective of the study was to evaluate FISH on peripheral blood specimen as a rapid and reliable method to quantify Ph positive cells in a patient with Chronic Myeloid Leukaemia. FISH was performed on interphase nuclei from cultured peripheral blood sample of the patient using BCR/ABL Translocation, Dual fusion probe. Chromosomal analysis was performed by GTG banding technique. FISH and karyotyping confirmed the presence of reciprocal translocation t (9; 12) (q34.1; q11.2).Our results confirmed that FISH technique is a rapid, sensitive, quantitative technique which can be used for the evaluation of CML using peripheral blood. FISH helps in the detection of minimal residual disease and disease recurrence with small percentage of abnormal cells. In our experience, this situation is usually associated with very high WBC count which can result in increase in the percentage of Phpositive cells.
Endovascular stenting for treatment of superior vena cava syndrome
Authors: K. Subramanyam , Kamath Janardhan , Johny Dilip , Joyes Paul T. 
Published: April 2020

AbstractSuperior vena cava syndrome (SVCS) is a well-known manifestation of benign and malignant tumors of the upper mediastinum. Superior vena cava (SVC) obstruction and thrombosis caused by indwelling venous catheters is a growing problem in patients on regular haemodialysis. We present a 62-year-old woman with typical signs and symptoms of SVCS, secondary to thrombosis surrounding the indwelling central catheter who was treated with endovascular stenting by the percutaneous approach. We obtained both procedural success with complete restoration of blood flow and immediate relief of symptoms.
Effectiveness Magnesium Sulphate Crystal Fomentation Vs Paste Application for Phlebitis among Children Receiving Peripheral Infusion who are Admitted at Selected Hospital at Mangalore
Authors: D'souza Brincy Loyolla ,   Shivakumar
Published: April 2020

Abstract
Background: Peripheral cannulation is one of the commonly used procedures in children, as they have to undergo many infusions for the administration of medications. The nurse is responsible for maintaining and monitoring IV infusion site and promptly detecting any complication like phlebitis, infiltration, air embolism, infection and fluid overload. In children phlebitis is the most commonly seen due to their fragile veins and therefore special attention should be given to minimize the occurrence of phlebitis and also to treat it effectively.
Objective: to determine the effectiveness magnesium sulphate crystal fomentation vs glycerin magnesium sulphate paste application for phlebitis among children receiving peripheral infusion.
Setting & Design:Regional Advance Pediatric Care Center (RAPCC), Mangalore.
Material and Methods: Quasi experimental design phlebitis measurement chart and observation checklist for erythema.
Result and Conclusion: the mean pre-treatment scores of phlebitis were significantly reduced after the treatment with magnesium sulphate fomentation and with glycerin magnesium sulphate paste application. The mean post treatment score of phlebitis at p<0.05. Glycerin magnesium sulphate paste was effective in reducing swelling and induration when compared to magnesium sulphate crystal fomentation.
Validation of Standard of Living Scale with Comparison to Other Socio-Economic Scales in a Semi Urban Area of Mangalore : A Pilot Study
Authors: Priyadarisini N. J. , K. Rashmi , Kiran N. Udaya , Badiger Sanjeev 
Published: April 2020

Abstract
Introduction: Socioeconomic status is an important determinant of health condition of an individual or a family. Many tools are being used to assess the socioeconomic status. Each of the scales have their own advantages and disadvantages. But an appropriate and a standardized tool is yet to be developed
Objectives: To compare the standard of living based on different socioeconomic scales in a semiurban area of Mangalore and to assess the appropriateness of socioeconomic scales to be used in a semiurban area of Mangalore
Methodology: A cross sectional study was conducted in households of Kuthar and Manjanady villages of Dakshina Kannada district from June- August 2014. Questionnaire method was used to avail information about the socioeconomic status of the study population. The data was analysed using SPSS 16 software.
Results: Majority (70%) of the study population belonged to class IV of kuppuswamy scale. Whereas according to Modified BG Prasad scale majority of the population belonged to class III (35%) and class II (28%). According to Pareek's scale around 92% of population belonged to class IV. But when standard of living was assessed majority of them (62%) had high standard of Living.
Conclusions: We found that Standard of living is the better option in assessing the socio-economic status of a household as compared to all other scales whether be it urban, rural or semi urban.
Congenital Syndactyly of the Fingers : A Report of Two Cases
Authors: Shetty Sanath Kumar , Hegde Anoop , Mathias Lawrence John , Rai H. Ravindranath 
Published: April 2020

AbstractSyndactyly is defined as the failure of separation of the digits during early gestation. It is one of the most common congenital anomalies. The incidence of syndactyly is uncertain, but estimates range from 1 in 2,500 live births. During development, the fingers are webbed. This remains so, until apoptosis and skin recession allow for formation of the digital interspaces. Full inter-digital spaces are usually present by the end of the 6th week of gestation.Here we present two patients and three hands who presented to us with syndactyly of the fingers. The first patient who was a 13 year old girl, had complete complex syndactyly between the ring and middle fingers of both hands. She underwent complete release with full thickness skin grafting in the first sitting. Six weeks later, she was reviewed and was noted to have developed scar contracture of the middle finger for which she underwent contracture release and z-plasty as a secondary procedure. In the final review at four months after the second surgery, the child was noted to have only terminal restriction of movements of the involved fingers of both hands with 'fair results' (as per the criteria of Cortez et al).The second patient was a two years old boy, who presented to us with incomplete simple syndactyly of the ring and index finger of the left hand. He was managed with percutaneous release of the syndactyly. He was reviewed after 4 months and there was full range of movement of the involved digits. He was also noted to have 'fair results' (as per the criteria of Cortez et al).As we had two different cases with a heterogenous presentation of two different types of syndactyly and who underwent different modalities of management, we are presenting it as an interesting case report in our article.
Laparoscopic Marsupialization of a Giant Non-Parasitic Splenic Cyst (Npsc) in the Paediatric Age Group
Authors: Amonkar Amol Dilip , Raghushankar Raghushankar , Rai Sandeep , Khan Sattar , Ganesh G.V. 
Published: April 2020

AbstractNonparasitic splenic cysts are rare clinical lesions of the spleen. The management has entailed partial or total splenectomy via an open approach. Recently, laparoscopic approaches have been developed. In this report, we describe laparoscopic marsupialization of a giant splenic cyst (diameter > 15 cm).A 15-year-old Indian child presented with a four and a half year history of mass in upper left quadrant associated with left upper quadrant pain which increased since 2 days. Physical examination revealed a large, nontender left upper quadrant mass with minimal movement on respiration. Computed tomography scan confirmed a cyst arising from the spleen, measuring 20 x 15 cm suggestive of a primary splenic cyst. Echinococcus and Entamoeba histolytica serologies were negative. Laparoscopic exploration was performed. three liters of brown fluid were aspirated and intraoperative cytology confirmed a nonparasitic cyst. The cyst wall was excised, preserving the spleen. The patient's recovery was uneventful, and he was discharged, tolerating a regular diet on postoperative day 3. At follow-up, the patient was asymptomatic and showed no evidence of recurrence. Non-parasitic splenic cysts are rare lesions. Laparoscopic marsupialization is safe and effective and should be considered the treatment of choice even for giant splenic cyst.
A Descriptive Study on Cultural Practices about Menarche and Menstruation
Authors: Leena Sequira ,   Soumya
Published: April 2020

AbstractA descriptive study on cultural practices about menarche and menstruation was done with the objective to identify the cultural practices related to menarche and menstruation among women and to compare the difference in the cultural practices of different religions. A survey approach was used and subjects aged 18years and above were included in the study. Data were collected using demographic proforma and practice questionnaire on menarche and menstruation. Findings of the study revealed that 37% of the sample celebrates menarche and th 13% of the sample offered special pooja after 7th day of menarche.83% of the sample does not offer pooja/namaz and visit temple during menstruation. 68% of the sample do not apply kumkum which is offered to God. Hindus practice different practices like not applying the kumkum (100%) which is offered to God, do not visit temples (100%), enter the pooja room (92%), attend the religious functions (100%). where as Christians are not following any practices and Muslims (100%) cut nails, shave private part and are not doing namaz for seven days.
Conclusion: The findings of the present study revealed that majority of the Hindus believe that menstruation is unclean and they follow different practices.
Awareness on epidemiological factors of HIV/AIDS among nursing students in selected institutions in Dakshina Kannada
Authors: Kamath Neetha 
Published: April 2020

Abstract
Introduction: An integrated approach is strongly suggested for creating knowledge, attitudes, and awareness to control the spread of HIV/AIDS among young people as well as health care students.
Objectives: To determine the awareness on epidemiological factors of HIV/AIDS among nursing students.
Methodology: A quantitative approach with descriptive design was found suitable to conduct the study among 700 first year B Sc nursing students were selected using cluster sampling method from different nursing institutions. After obtaining the consent from the subjects a pretested and valid questionnaire on HIV/AIDs was administered to collect the data.
Results: All the students had information (86.1%) on HIV/AIDS mainly from T.V/Radio. It was found that majority of the subjects (63.3%) had poor awareness, 31.6% had average and only 5.1% of subjects had good awareness on HIV/AIDS.
Conclusion: It is evident from the study findings that the nursing students lack awareness on epidemiological factors of HIV/AIDs there is a need to have an education program before they are active in caring for the patient in hospital.
Effectiveness of Integrated Teaching Module among Final Year Medical students
Authors: Aroor Akshatha Rao , S. Dileep K. , Saya Rama Prakasha , Rao Sudheendra 
Published: April 2020

AbstractBackground: Didactic lectures and the current practice of teaching in Medical colleges has many limitations. Correlation and integration of knowledge into practice becomes difficult in the absence of integrated teaching at appropriate levels in medical curriculum.Aim: To assess the effectiveness of the vertical integrated teaching method among the final year MBBS students and to study the attitude towards integrated teaching. Materials and Methods: This is a prospective study conducted among 102 final year MBBS students at a tertiary care medical college hospital in South India. The teaching was implemented by the active participation of faculty from the departments of Physiology, Pathology and General Medicine on a single topic. Students' knowledge about the subject before and after the session was evaluated by a questionnaire of 20 questions (Pre-test and Post-test). The mean score before and after the session was compared using the paired't' test. The students were also asked to give their feedback about the usefulness of this method in improving their knowledge.Results: The mean scores before and after the session were 8.8± 2.87 and 16.88±1.23 (p value < 0.001). Majority of the students (97.1%) opined the need for integrated teaching to be a part of medical curriculum. Most of them (54.9%) felt the need for integrated teaching to be conducted monthly. On self-grading the knowledge on a scale of 1 to 10 before and after the session, the mean scores were 4.73±1.84 and 7.83±1.86 respectively (p value < 0.001). Conclusion: The integrated teaching was found to be an effective method of teaching. Medical students had a positive attitude towards integrated teaching.
A Study To Assess The Effectiveness Of A Planned Teaching Programme On Diabetes Mellitus And Its Management Among Asha Workers In Selected Areas Of Udupi District, Karnataka.
Authors: Thomas Monica Tonia , George Mariamma V. , Devi Elsa Sanatombi 
Published: April 2020

Abstract
Background: Diabetes is a chronic metabolic disorder which is prevalent throughout the world. ASHA workers are the grass root workers who have direct contact with the people in the community who can be of great help in empowering the diabetes individuals in their management.
Methods: The study used evaluative approach with one group pre-testpost-test design. Sixty ASHA workers of selected PHC's and CHC''s of Udupi District were selected for the study using non probability convenient sampling, technique. The instruments used for the study were Demographic Proforma, structured knowledge questionnaire on diabetes mellitus and its management. Descriptive and inferential statistics were used for analysis of the data.
Results: Majority 42(70%) of ASHA workers belongs to the age group of 31-40yrs and 28 (46.7%) of them had experience as ASHA worker with high school education. In the pre-test 17(28.3%)of ASHA workers had poor knowledge but in post-test, 28(46.7%) of them gained good knowledge which indicated that the planned teaching programme on diabetes mellitus and its management was found to be effective in improving the knowledge of ASHA workers. (T value- 14.226, p value -0.002).
Conclusion: The study concluded that the teaching programme was effective in bringing desirable changes in knowledge of ASHA workers.
A Submandibular Sialolith of an Unusual Size Presenting With a Cervical Fistula Mimicking a Branchial Fistula: A Case Report
Authors: Ballal Rajesh , Banu KhamarJaha , Pandya Kalpa 
Published: April 2020

AbstractSialoliths greater than 10 mm in size can be called as those of an unusual size. Only 7.65 % of the sialoliths are >15 mm. Cutaneous fistulas due to submandibular sialoliths are even rarer. A case of a submandibular gland sialolith of an unusual size presenting with a cervical fistula mimicking a branchial fistula has been reported. Intra-operatively, the fistulous tract was found to extend upto the supraclavicular space. Complete excision of the gland along with fistulous tract was performed. Histopathology revealed a sialolith with acute and chronic sialedinitis. The lesion also mimicked a Kuttnor's tumour however a final diagnosis of the same could not be made due to inconclusive Ig G value and absence of plasmacytic infiltration.
Dialysis Dependent 'Double Positive Disease' Responding To Immunosuppression: A Case Report
Authors: Baikunje Shashidhar , Vankalakunti Mahesha , Bhandary Adithi , Prakash P.S. 
Published: April 2020

AbstractThe outcome of patients with crescentic nephritis and the presence of both ANCA and anti GBM disease (double positive disease) is controversial. Initial data supported the view that this condition has a more favorable prognosis than anti GBM disease but larger and more recent series found much worse renal outcome especially in patients with severe renal failure requiring dialysis. We present a case with severe renal failure due to double positive disease who recovered renal function with aggressive immunosuppression including steroids, cyclophosphamide and plasma exchange.
A Rare Case of Fulminant Toxic Shock Syndrome Associated with Clostridium Sordellii Septic Abortion
Authors: Elagwany Ahmed S. , Anas Nehal 
Published: April 2020

AbstractEndometritis and toxic shock syndrome associated with Clostridium sordellii havepreviously been reported after childbirth and, in one case, after medical abortion. Clinical findings included tachycardia, hypotension, edema, hemoconcentration, profound leukocytosis, and absence of fever. We describe a young woman who developed Clostridium sordellii toxicshock syndrome after having had an abortion surgically evacuated five days before admission to our hospital. Although the patient was aggressively treated, death occurred <3 days after admission. It is hoped that very early recognition of this disease will decrease the mortality associated with this rarely reported ailment.
Lower Third Molar Space and Angulation in Individuals with Lower Anterior Crowding
Authors: Cherian Merin , Ravi M. S. 
Published: April 2020

Abstract
Background: The role and involvement of mandibular third molars on mandibular incisor crowding, post retention, in orthodontically treated patients has long been debated. The correlations between lower anterior crowding and lower third molar angulation and space are not completely understood.
Aim: To assess the lower third molar space and its angulation in individuals with lower anterior crowding and to compare it with that of individuals without lower anterior crowding.
Settings and design: Hospital based Prospective, cross-sectional study on randomly selected individuals.
Materials and Methods: Lower third molar space and angulations were measured and compared using orthopantomograph tracings of 80 subjects in the age group of 20-30 years with skeletal Class I malocclusion individuals without lower anterior crowding(Group A) and individuals with lower anterior crowding (Group B).
Statistical Analysis: Both the space and angulations of lower third molar were correlated with the lower anterior crowding using Pearson Correlation Coefficient.
Results: Significant differences were found in third molar space between the study group and the control group. But there was no significant difference in third molar angulation between the groups.
Conclusion: the lower anterior crowding has a significant influence on third molar space but did not have any effect on third molar angulation.
Quality Of Life in Stroke Patients - A Qualitative Study
Authors: Shetty Soniya , Kundapur Rashmi ,   Sricharan
Published: April 2020

Abstract
Introduction: In India stoke is a leading cause of death and acquired human disability. A review of stroke outcome measures in 174 acute stroke trials showed that death was recorded in 76%, impairment in 76%, disability in 42% and handicap in only 2%. One dimension that is rarely measured is health-related quality of life (HRQOL) which aims to assess the impact of disease from the perspective of the patient. Although there is an association between neurological deficits and QL, they are not synonymous.
Objectives: study the health related quality of life with patients of stoke within 3 months of stroke.
Methodology: Study Settings: Hospital based study- A continuation of Stroke RegistrySample Size: We took 20 patients from the registryThe patients with fresh stoke attack and also who were attending the follow up within the first 3 months of the attack was enrolled into the study. Basic demographic data and the data of stroke outcomes were taken. HRQOL was evaluated using the WHO BREF.
Results: It was seen that majority (55%) of patients expressed a fair physical domain post stroke. About 40% were of opinion that their physical domain was poor. Assessing the psychological domain, majority of the patients said it was poor, 40% said that it was fair. About half (50%) of the patients showed that they had poor environmental domain, whereas only 35% it was fair.
Conclusion: The quality of life is hampered by stroke in majority of the patients.
Enhancement of Flexural Strength of Two Nano-composites by Electron Beam Irradiation
Authors: Hegde Mithra N. , Shetty Preethesh , Bhat Raksha , Mathew Tony 
Published: April 2020

Abstract
Aim: The study aimed to assess and investigate the effect of electron beam irradiation on the flexural strength of two newer nanocomposites (Filtek Z350XT and Filtek Bulkfill)
Materials and Methods: Forty samples each of both the nanocomposites were prepared on rectangular bar shaped moulds (25*2*2mm) according to ISO 4049. The dosage of electron beam selected for the study were 2KGy, 4KGy and 10KGy. The forty specimens were divided into four groups based on the radiation doses; group I: non radiated, group II: 2KGy , group II: 4 KGy, group II: 10KGy with ten samples in each group. The samples were subjected to a 3point bend test on a universal uniaxial servo mechanical testing machine.
Results: The data was statistically analyzed using One way Anova analysis. Analysis demonstrated that Filtek Z350XT had better flexural strength than Filtek Bulkfill (P<0.001). The flexural strength of the composites increased with the dose of electron beam irradiation.
Conclusion: Within the limitations of the study, it can be concluded that the electron beam irradiation of the nanocomposites can be used as a tool to enhance their mechanical properties.