bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kemampuan Problem-solving Skills Calon Guru PAI Berdasarkan Gender dan Grade Levels
Authors: Fadli Adi 
Published: November 2020

Abstrak
Penelitian ini bertujuan untuk mendeskripsikan kemampuan problem-solving skills (PSS) calon guru Pendidikan Agama Islam (PAI) berdasarkan gender dan grade levels. Sampel penelitian terdiri dari 100 orang calon guru PAI (60 wanita dan 40 laki-laki) yang ditentukan melalui teknik cluster random sampling. Design penelitian menggunakan cross-sectional survey dan dianalisis dengan uji MANOVA. Instrumen penelitian yang digunakan untuk mengukur kemampuan problem-solving skills (PSS) dengan mengacu pada Instrumen problem solving essay test (PSET) yang dikembangkan oleh Polya. Hasil penelitian membuktikan bahwa; (1) tidak terdapat perbedaan kemampuan problem-solving skills (PSS) calon guru PAI berdasarkan gender; (2) terdapat perbedaan kemampuan problem-solving skills (PSS) calon guru PAI berdasarkan grade levels; (3) grades junior memiliki level PSS yang paling tinggi dibandingkan pada grades freshman dan sophomore.
Abstract
This study aims to describe the ability of problem-solving skills (PSS) preservice Islamic teachers (PAI) based on gender and grade level. The research sample consisted of 100 PAI teacher candidates (60 women and 40 men) determined through cluster random sampling techniques. The study design used a cross-sectional survey and analyzed it with the MANOVA test. The research instrument used to measure the ability of problem-solving skills (PSS) with reference to the problem-solving instrument essay test (PSET) developed by Polya. The results of the study prove that; (1) there is no difference in the ability of PAI teacher candidates to solve their problem-solving skills based on gender; (2) there are differences in the ability of PAI teacher candidates to solve problem-solving skills (PSS) based on grade levels; (3) junior grades have the highest PSS level compared to freshman and sophomore grades.
UPAYA DERADIKALISASI AGAMA (PENGEMBANGAN BAHAN AJAR AQIDAH-AKHLAK BERBASIS HUMANISTIK)
Authors: Arifin M. Anugrah , Najamudin Najamudin 
Published: November 2020

Penelitian ini bertujuan untuk membahas perihal peyusunan dan pengembangan bahan ajar Aqidah-Akhlak berbasis humanistik sebagai upaya deradikalisasi agama. Penelitian ini menggunakan desain pengembangan yang dikenalkan oleh Borg & Gall yaitu Educational R & D atau Research-Based Development dengan 7 tahapan. Populasi penelitian ini adalah mahasiswa Fakultas Pertanian Universitas Muhammadiyah Mataram yang terdiri dari 2 Program Studi yaitu; Teknologi Pertanian (TP) dan Teknologi Hasil Pertanian (THP). Adapun sampel ditentukan berdasarkan keterpenuhan kebutuhan (purposive sampling). Hasil temuan penelitian ini menunjukkan bahwa sebagian besar mahasiswa kurang memahami hakikat agama Islam, ketetapan Allah (taqdir), iman, Islam, dan konsep Islam tentang pergaulan dalam bermasyarakat, berbangsa, dan bernegara, termasuk mengenai isu khilafah. Penelitian ini menghasilkan sebuah bahan ajar Aqidah-Akhlak berbasis humanistik yang terdiri dari 4 BAB; Islam sebagai way of life, manusia dan taqdir, Islam dan pergaulan dalam masyarakat, serta akhlak bernegara.
KAJIAN PAI PARA PELAJAR DALAM PUSARAN DUNIA VIRTUAL
Authors: Fuadi Abdulloh 
Published: November 2020

Abstrak
Pusaran dunia virtual terkini mengisyaratkan diperlukannya penelusuran tentang pemahaman para pelajar post-millenial yang terkungkung dalam dunia virtual yang digitalistik terhadap ajaran dasar agama Islam, yang terangkum dalam kajian dalam bidang Pendidikan Agama Islam. Dengan menggunakan metode kualitatif beserta berbagai perangkatnya, dan mendasarkan pada pemikiran tentang ruang publik virtual, penelitian ini mengungkapkan bahwa kesan ketegasan dan kekuatan terpancar dalam uraian para pelajar saat mereka mengungkapkan pemahaman mereka tentang makna agama Islam, pokok-pokok ajaran, sejarah, dan isu-isu keagamaan terkini.
Kata kunci: Ajaran Dasar Agama; Pelajar; Ruang Publik Virtual.

Abstract
The latest virtual world vortex suggests the need for a search to understand post-millennial students who are confined in a digitalistic virtual world toward the basic teachings of Islamic religion, summarized in the study of Islamic Religious Education. Using qualitative methods and their various tools, and based on thinking about virtual public spaces, this study revealed that the impression of assertiveness and strength radiated in students' description as they expressed their understanding on the meaning of Islam, the main points of teachings, history, and current religious issues.
Keywords: Basic Teachings of Religion; Student; Virtual Public Spaces
THE INFLUENCE OF AQIDAH AKHLAK AND SOCIOLOGY LEARNING OUTCOMES ON THE FORMATION OF STUDENT CHARACTER
Authors: Astuti Eva Karlina Dwi , Tarsono Tarsono , Suryani Yani 
Published: November 2020

Abstract
This study aims to determine the effect of moral theology learning outcomes and sociology learning outcomes on the formation of student character. This research uses a quantitative approach because the data presented is in the form of numbers. The method used is descriptive correlational. The research subjects were taken from 26th grade XI students. Data was collected using test, documentation and observation methods. Data were analyzed using IBM's SPSS version 26 application program. Hypothesis testing is done by statistical analysis techniques that are using multiple linear regression test. Based on the results of the study concluded that there is an influence of moral theology learning outcomes and sociology learning outcomes together can have an influence on student character. It is proven that the significance value of the regression in the ANOVA test table is 0,000 (<0.05), then Ho is rejected and H1 is accepted. The magnitude of influence is equal to 57.7%.
Keywords: Learning outcomes; moral theology; Sociology; Character building.
ECO-PESANTREN AS THE PANACEA FOR GLOBAL CLIMATE CHANGE: LESSONS FROM NURUL HARAMAIN NW LOMBOK ISLAMIC BOARDING SCHOOL INDONESIA
Authors: Quddus Abdul 
Published: November 2020

This paper examined the ecological concept and its implication at Nurul Haramain NW Lombok Islamic boarding school in response to the world climate crisis. Boarding schools have the potentials to bridge the environmental conservation initiative amid the secular science phenomena. This study employed a descriptive-explorative approach using a qualitative methodology. Thus, theoretically, this study was anchored in Mary Evelyn Tucker and Vasudha Narayan's theories of eco-theology in addressing the climate crisis. The findings showed that Nurul Haramain NW Lombok Islamic boarding school had implemented a sustainable lifestyle based on the ecological values in the Al-Quran and Hadith, in which Tuan Guru as the environmental conservation foreman.

Keywords: Eco-Pesantren, Climate Change, Environmental Crisis, Educational Theology, Eco Theology
Effects of contact stress on patellarfemoral joint and quadriceps force in fixed and mobile-bearing medial unicompartmental knee arthroplasty
Authors: Kwon Hyuck Min , Lee Jin-Ah , Koh Yong-Gon , Park Kwan Kyu , Kang Kyoung-Tak 
Published: November 2020

Abstract
Background Unicompartmental knee arthroplasty (UKA) is an effective treatment for end-stage, symptomatic unicompartmental osteoarthritis of the knee joint. However, patellofemoral joint degeneration is a contraindication to medial UKA. Therefore, the objective of this study was to evaluate the biomechanical effect of medial UKA using fixed-bearing (FB) and mobile-bearing (MB) design prostheses on the patellofemoral joint. Methods A three-dimensional finite-element model of a normal knee joint was developed using medical image data. We performed statistical analysis for each model. The differences in contact stress on the patellofemoral joint and the quadriceps force between the FB and MB designs were evaluated under a deep-knee-bend condition.Results At an early flexion angle, the results of contact stress showed no significant difference between the FB and MB medial UKA models and the intact model. However, at large flexion angles, we observed a significant increase in contact stress with the FB models. On the contrary, in the case of the MB models, we found no statistically significant increment compared with the intact model. Our results indicate that with medial UKA, the contact stress increased and greater quadriceps force was applied to the patellofemoral joint. However, performing UKA on a patellofemoral joint with osteoarthritis should not be difficult, unless anterior knee pain is present, because the increase in contact stress is negligible. Conclusions Our results show no significant difference in contact stress on the patellofemoral joint between the medial UKA and intact knee joint models. Such a mechanism was easily found in MB medial UKA. Therefore, this study biomechanically showed that degenerative changes in the patellofemoral joint should not be considered an absolute contraindication to treatment with medial UKA.
Reducing the use of empiric antibiotic therapy in patients on admission to the hospital with COVID-19
Authors: Pettit Natasha N. , Nguyen Cynthia T. , Lew Alison , Bhagat Palak , Nelson Allison , Olson Gregory , Ridgway Jessica , Pho Mai T. , Pagkas-Bather Jade 
Published: November 2020

Abstract
Background: Empiric antibiotics for community acquired bacterial pneumonia (CABP) are often prescribed to patients with COVID-19, despite a low reported incidence of co-infections. Stewardship interventions targeted at facilitating appropriate antibiotic prescribing for CABP among COVID-19 patients are needed. We developed a guideline for antibiotic initiation and discontinuation for CABP in COVID-19 patients. The purpose of this study was to assess the impact of this intervention on the duration of empiric CABP antibiotic therapy among patients with COVID-19. Methods: This was a single-center, retrospective, quasi-experimental study of adult patients admitted between 3/1/2020 to 4/25/2020 with COVID-19 pneumonia, who were initiated on empiric CABP antibiotics. Patients were excluded if they were initiated on antibiotics >48hours following admission or if another infection was identified. The primary outcome was the duration of antibiotic therapy (DOT) prior to the guideline (March 1 to March27, 2020) and after guideline implementation (March 28 to April 25, 2020). We also evaluated the clinical outcomes (mortality, readmissions, length of stay) among those initiated on empiric CABP antibiotics. Results: A total of 506 patients with COVID-19 were evaluated, 102 pre-intervention and 404 post-intervention. Prior to the intervention, 74.5% (n=76) of patients with COVID-19 received empiric antibiotics compared to only 42% of patients post-intervention (n=170), p<0.001. The median DOT in the post-intervention group was 1.3 days shorter (p<0.001) than the pre-intervention group, and atypical antibiotic DOT was reduced by 2.8 days (p<0.001). More patients in the post-intervention group were initiated on antibiotics based on criteria consistent with our guideline (68% versus 87%, p=0.001). There were no differences between groups in terms of clinical outcomes. Conclusion: Following the implementation of a guideline outlining recommendations for initiating and discontinuing antibiotics for CABP among COVID-19 inpatients, we observed a reduction in antibiotic prescribing and DOT. The guideline also resulted in a significant increase in the rate of guideline-congruent empiric antibiotic initiation.
On the frontline—Sustainability and development research amidst the COVID-19 pandemic
Authors: Gatto Andrea , Drago Carlo , Ruggeri Matteo 
Published: November 2020

Abstract
COVID-19 outbreak has exposed the world population to a condition of unprecedented public health and global health vulnerability. Preliminary and projected consequences have exhibited their harmfulness for socio-economic, environmental and political systems. In this framework, development and sustainability turn focal policy targets to limit the humanitarian and ecosystems impacts of the pandemic and stimulate mitigation, preparedness and adaptation to change. This work aims at furnishing a prompt array of key tools to analyse, comprehend and disentangle the sketched issues. For this scope, it is conducted a bibliometric analysis for depicting and mapping the early scholarship response on the relationship between the 2019 Coronavirus, sustainability and development within the pandemics discourse. The research finds a relevant bulk of early publications and geographical insights, principally published on environmental and economic policy, global and public health journals by US, UK, Chinese and Italian scholars. Exploiting a multiple correspondence analysis and a validated cluster analysis, the investigation detects a conceptual structural map made up of clusters of issues – environmental health, socio-economic and medical/technical topics, that can be related to the different phases of the Coronavirus. The outputs confirm the need for rapid sustainability action within the development policy to contrast the pandemic.
Global-scale episodes of transoceanic biological dispersal during the Cenozoic
Authors: Viete Daniel , Cooke Siobhán 
Published: November 2020

Abstract
Since formalization of plate tectonic theory in the 1960s, vicariance has been the dominant model for interpretation in biogeography. However, modern research suggests transoceanic ‘rafting’ is also an important process in biological dispersal. Here we show that Cenozoic occurrences of rafting-associated colonization of new lands by terrestrial biota are not randomly distributed in time, but cluster at c. 40 million years ago (Ma) and c. 15 Ma. These excursions in rafting activity are reflected across taxonomic groups and ocean basins. The global scale and ~25 million-year (My) wavelength of the fluctuations suggest they are associated with planetary-scale changes and/or events.
Manipulation of Localised Nutrient Placement to Enhance Synergistic Effects of Nitrogen and Phosphorus for Rice&nbsp;
Authors: Lu Dianjun , Song Hang , Chen Xiaoqin , Wang Huoyan , Zhou Jianmin 
Published: November 2020

Abstract
Background: Point application of fertiliser containing only immobile phosphorus (P) at a site distant from crop roots may limit plant P capture and grain yield. We investigated whether a localised application of P together with nitrogen (N) could offset this limitation in rice (Oryza sativa L.). We postulated that N in this combined fertiliser would stimulate root proliferation, thereby promoting uptake of P. Results: We conducted a pot experiment using three localised nutrient supply treatments (N-only, P-only, and combined N and P) applied at sites near (3 cm) and distant (10 cm) from rice seedlings. We also tested the effects of homogeneous NP supply. Grain yields were similar between the homogeneous NP supply and localised N-only supply, regardless of placement distance. P-only supply with 10 cm placement reduced grain yield by 30%. Root length density was considerably greater around the placement site in the localised N-only treatment compared to the P-only at both placement distances. Hence, localised combined N and P supply offset reductions in yield and nutrient uptake realised under the P-only supply with 10 cm placement. Root mass density and root/shoot dry weight ratio were greater under the localised N-only supply than in the NP combination with 3 cm placement. Hence, localised combined N and P supply with 3 cm placement enhanced grain yield (by 33%) than the N-only supply. Conclusion: The synergistic effects of localised fertilisation with N and P can be maximised through precise manipulation of specific placement distances for favourable root architecture and high crop yield.
High selectivity to ethanol gas sensor based on ZnO nanosheets decorated with Ag nanoparticles by aqueous solution and photochemical deposition
Authors: Young Sheng-Joue , Liu Yi-Hsing 
Published: November 2020

Abstract
We demonstrated the fabrication of Ag NPs decorated ZnO NSs on a glass substrate using the aqueous solution and photochemical deposition method. The synthesis process is room temperature. This two-dimensional ZnO NSs can increase the performance of gas sensors due to increase the surface-to-volume ratio. Through increasing the surface-to-volume ratio of nanostructures, it is possible to increase the absorption potion of the target gas. In addition, noble metal NPs attached to the ZnO nanostructure can also increase the performance of gas sensors because Ag NPs act as strong electron acceptors, it will be induced enhanced electron depletion layer. As a result, the Ag NPs decorated ZnO NSs gas sensor has high selectivity to ethanol, as well as improved gas sensing performance to ethanol as compared to ZnO.
Gender as a factor affecting the NK cell activity in patients successfully treated for chronic hepatitis C with DAA
Authors: Zientarska Agata , Witkowska Aleksandra , Rozpłochowski Błażej , Mikuła-Pietrasik Justyna , Kaczmarek Mariusz , Kowala-Piaskowska Arleta , Książek Krzysztof , Żeromski Jan , Mozer-Lisewska Iwona 
Published: November 2020

Abstract
Chronic hepatitis C (CHC) affects the activity of NK cells, but successful interferon-free treatment partially restores it. The goal of the study was to assess whether gender influences those alterations. We examined 21 women after menopause and 24 men with CHC treated with directly acting antivirals (DAA), and 33 healthy volunteers. With flow cytometry, we analysed KIR2DS4, NKG2D, NKp30, KIR2DL2/DL3, NKG2A, TRAIL and granzyme B on the surface of NK cells, simultaneously we checked serum CXCL10 with ELISA. Overall, patients with CHC had higher expression of KIR2DS4, NKG2A, NKp30 and a lower percentage of NK cells among lymphocytes than the control group. After the treatment KIR2DS4, KIR2DL2/DL3 and NKG2A, TRAIL NKp30 on NK cells decreased, while the percentage of NK cells, expression of granzyme B and NKG2D increased. Serum CXCL10 was elevated before the treatment and dropped afterwards. We observed differences between genders in the expression of KIR2DL2/DL3 (higher in female) and NKp30 (elevated in men) comparing CHC/control groups. After the treatment of KIR2DL2/DL3, NKp30 and CXCL10 dropped only in female while granzyme B increased in male. In conclusion, the response of NK cells among men and women in post-menopausal age with CHC differs. Our research may lead to more studies on different nature of female and male immune systems in the context of HCV infection and treatment.
Downregulation of Cardiotrophin-Like Cytokine 1(CLCF1) Inhibits Osteoblastic Differentiation by Regulating RANKL/ OPG Pathway
Authors: Chen Juan , Xu Huijuan , Ye Yunjing , Xie Lihua , Li Shengqiang , Ge Jirong 
Published: November 2020

Abstract
BackgroundCardiotrophin-like cytokine factor 1 (CLCF1) is a member of the IL (interleukin)-6-type cytokine. Although its immunomodulatory functions are well defined, data on the physiological and pathological functions of the CLCF1 in bone metabolism remains scant. Here, we interrogated the functions and mechanisms of CLCF1 in osteoblast differentiation.MethodsA total of 109 patients with postmenopausal osteoporosis (PMOP) and 94 control group participants were included in this study. Quantitative reverse transcription PCR (RT-qPCR) and Western blot techniques were used to profile the expression of the CLCF1, nuclear factor-kB ligand and its decoy receptor osteoprotegerin (RANKL/OPG), as well as the janus activated kinase (JAK2)/transcription3 (STAT3) pathway. To elucidate the effect of CLCF1 on bone metabolism, we established CLCF1 gene-knockout Raji cell lines and Raji-MG-63 co-culture system, and interrogated the osteoblast differentiation by measuring the activity of ALP and the level of Alizarin-Red S staining.ResultsOur data demonstrated that the expression of CLCF1 was highly downregulated in PMOP compared with the control group. Moreover, the level of CLCF1 was proportional to the bone mineral density (BMD) in the postmenopausal osteoporosis. Furthermore, the deletion of CLCF1 gene inhibits osteoblast differentiation by regulating the RANKL/OPG system.ConclusionOur findings unravel the previously unidentified roles of CLCF1 in the bone-immune crosstalk, as well as potential therapeutic strategies for postmenopausal osteoporosis.
Prognostic value of Serum miR-217 Level in Osteosarcoma Patients
Authors: Ye Jia , Jin Zhi-Hui , Chen Ren , Chen Sen , Ren Yi-Jun , Guo Wei-Chun , He Hui 
Published: November 2020

Abstract
Background: MicroRNA (miR)-217 is a tumor suppressor significantly associated with osteosarcoma. We try to evaluate serum levels miR-217 in osteosarcoma patients and evaluate its prognostic significance.Methods: A total of 163 consecutive osteosarcoma patients and 96 healthy participates were enrolled. Serum miR-217 levels were evaluated by using real-time quantitative reverse transcription polymerase chain reactions (RT-PCR). The association between serum miR-217 level and survival outcomes was evaluated by univariate and multivariate analysis. Results: Serum miR-217 levels in osteosarcoma patients was significantly lower than healthy volunteers (P<0.05). Low serum miR-217 was significantly related to advanced cancer and metastasis (both P<0.05). Moreover, patients with a low serum miR-217 had a poorer overall survival than those with a high serum miR-217 levels (P<0.05). Serum miR-217 level also been showed as independent risk factor for osteosarcoma in multivariate analysis (HR, 0.42; 95%CI: 0.12–0.98; p<0.01). Conclusions: Serum miR-217 levels was significantly downregulated in osteosarcoma patients and remarkably associated with poor prognosis, indicating that serum miR-217 might serve as a useful diagnostic and prognostic indictor for osteosarcoma.
Integrative Analysis of Genes Associated With Cancer Stem Cell Characteristics via Stemness Indices Combined With Multi-Omics Data in Liver Cancer
Authors: Zhang Jiecheng , Yu Binhong , Chu Haiwei , Hu Bin , Chen Luxia , Yang Weifang , Zhang Ruili , Zhao Wenjun 
Published: November 2020

Abstract
BackgroundLiver cancer (LC) is one of the most prevalent malignancies with a high morbidity and mortality. Cancer stem cells (CSCs) are capable of tumorigenicity, self-renewal and long-term survival. However, the relationship between LC and CSCs remains unclear.MethodsThe clinical data of LC patients and multi-omics data including mRNA-seq, lncRNA-seq, miRNA-seq, mRNA expression-based stemness index (mRNAsi), alternative splicing, DNA methylation and copy number variation (CNV) were obtained from The Cancer Genome Atlas (TCGA). Besides, the clinical data and RNA-seq of validation group were obtained from International Cancer Genome Consortium (ICGC). Integrative analysis of genes associated with CSCs characteristics were performed by stemness indices combined with multi-omics data in LC.ResultsThe stemness degree of cells in liver tumor group was higher than that of the normal group. The patients with high stemness degree of tumor tissue had significantly poorer overall survival. Besides, 6 methylation-driven genes and 4 CNV-driven genes related to CSCs characteristics were obtained. Alternative splicing factor regulatory network and ceRNA regulatory network were constructed respectively. Furthermore, the mRNAsi score of LC was negatively correlated with the tumor immune score. The proportion of CD8 T cell, activated memory CD4 T cell, follicular helper T cell and M1 macrophages was up-regulated in tumors with a higher degree of stemness. Finally, a prediction model was established, which has been proved to be a good predictor of prognosis by ICGC data.ConclusionsCancer cells with high degree of stemness aggravated the malignant progression of LC, which may be related to low immune infiltration. The proposed prediction model was a powerful predictor for patients and helpful to clinical work.