bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meningkatkan Nilai Jual Rajut Di Masyarakat Melalui Desain dan Media Sosial
Authors: Windanto Wisnu , Vanda Yoiceta 
Published: May 2020

<p>Kerajinan rajutan merupakan suatu produk rajutan hasil kerajinan tangan yang dilakukan secara manual. Tak sedikit produk fashion yang dibuat dari hasil rajutan, seperti baju, celana pendek, syal, sweeter, aksesoris, tas, dan produk yang lain. Berdasarkan permasalahan yang dihadapi oleh mitra, diperlukan suatu metode pendekatan yang sudah disepakati antara pihak Perguruan Tinggi dan pihak Mitra, yaitu : Pelatihan Internet, Pelatihan Merajut untuk ibu-ibu PKK, pelatihan Desain Grafis, Pembuatan Situs (World Wide Web). Kegiatan yang sudah dilaksanakan pada Program Kemitraan Masyarakat, adalah sebagai berikut : Pelatihan Merajut, Pelatihan Internet dan Pengelolaan Manajemen Website, pelatihan desain grafis.Setelah kegiatan ini dilaksanakan, ada beberapa kesimpulan yang dapat diambil, yaitu :Masyarakat sasaran yaitu ibu-ibu PKK, yang mempunyai usaha rumahan rajutan. masyarakat sasaran yaitu ibu-ibu PKK mendapatkan ketrampilan yang lebih baik untuk dapat menghasilkan produk-produk rajutan yang lebih inovatif, masyarakat sasaran mampu mengakses internet dan mengelola website sesuai dengan keinginan masing-masing. Setelah pembuatan Website, penjualan meningkat 10% dibandingkan dengan penjualan sebelum menggunakan website.</p><p> </p><p>Kata kunci: rajutan, website, pelatihan internet, pelatihan merajut.</p>
Goal Attainment Scaling Rehabilitation Improves Satisfaction with Work Activities for Younger Working Patients After Knee Arthroplasty
Authors: Hoorntje Alexander , Waterval-Witjes Suzanne , Koenraadt Koen L.M. , Kuijer P. Paul F.M. , Blankevoort Leendert , Kerkhoffs Gino M.M.J. , van Geenen Rutger C.I. 
Published: May 2020

Background:
Knee arthroplasty (KA) is increasingly performed in relatively young, active patients. This heterogeneous patient population often has high expectations, including work resumption and performance of knee-demanding leisure-time activities. Goal attainment scaling (GAS) may personalize rehabilitation by using patient-specific, activity-oriented rehabilitation goals. Since unmet expectations are a leading cause of dissatisfaction after KA, personalized rehabilitation may improve patient satisfaction. We hypothesized that, compared with standard rehabilitation, GAS-based rehabilitation would result in younger, active patients having higher satisfaction regarding activities after KA.

Methods:
We performed a single-center randomized controlled trial. Eligible patients were <65 years of age, working outside the home, and scheduled to undergo unicompartmental or total KA. The required sample size was 120 patients. Using GAS, patients developed personal activity goals with a physiotherapist preoperatively. These goals were used to monitor patients’ goal attainment and provide goal-specific feedback during postoperative outpatient rehabilitation. Standard rehabilitation consisted of regular outpatient physiotherapy visits. The primary outcome measures were visual analogue scale (VAS) scores (scale of 0 to 100) for satisfaction regarding activities of daily living and work and leisure-time activities 1 year postoperatively, which were analyzed using generalized estimating equation models.

Results:
Patient satisfaction with work activities was significantly higher in the GAS group (β = 10.7 points, 98% confidence interval [CI] = 2.0 to 19.4 points) than in the control group. Patient satisfaction with activities of daily living and leisure-time activities did not differ between groups. We found no differences in VAS satisfaction scores between unicompartmental KA and total KA.

Conclusions:
Personalized, goal-specific rehabilitation using GAS resulted in higher patient satisfaction with work activities, compared with standard rehabilitation, 1 year after KA.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Analysis of PONV incidence in gynaecology patients
Authors: Ćwiek Dorota , Wojciechowska Arleta , Szymoniak Katarzyna , Fryc Dorota , Stanisz Marta , Menkiszak Janusz 
Published: May 2020

Abstract

Introduction: Postoperative nausea and vomiting (PONV) is the most common side effect of anaesthesia, as reported by patients in the postoperative period. The overall incidence of PONV, according to various authors, is in the 8–92% range. The latest research on the pathophysiology of vomit reflexes has played an important role in changing the perception of PONV and introduction of PONV prevention, which significantly improves patient comfort by reducing the number of complications and shortening the length of the hospital stay.
The aim of the study was to analyse the incidence of PONV in gynaecological patients.

Materials and methods: The study was conducted among 300 women, patients of the Surgical Gynaecology and Gynaecological Oncology Clinic for Adults and Girls at the Independent Public Clinical Hospital No. 2 of the Pomeranian Medical University in Szczecin, who underwent surgery due to a variety of gynaeco-logical conditions in the period from May to October 2015. The research tool was the author’s own questionnaire containing 22 closed-ended questions. The questionnaire included demographics as well as an assessment of the state of the women’s health in terms of complications (nausea, vomiting), and substance use (tobacco, alcohol). Patient medical records were also analysed.

Results: The results demonstrated: 1) no relationship between the socio-demographic variables and the incidence of nausea and vomiting in the postoperative period; 2) no relationship between PONV and specific medical variables, such as alcohol use, body mass index (BMI), administration of opioids such as fentanyl and fentanyl plus morphine; 3) a relationship between the type of surgery, anaesthesia used, smoking, and the incidence of nausea and vomiting; 4) a high risk of nausea and vomiting in patients after administration of spinal morphine into the subarachnoid space; 5) metabolic diseases, diseases of the lower digestive tract, respiratory conditions, and motion sickness had a negative influence on the incidence of PONV.

Conclusions: 1. The type and duration of surgery as well as the type of anaesthesia and opioids used affected the incidence of nausea and vomiting in the postoperative period. If possible, every effort should be made to shorten the duration of surgery, perform surgery laparoscopically and administer drugs, which do not affect the incidence of nausea and vomiting. 2. There is a need for organisational changes in hospitals regarding the introduction and compliance with ERAS, in particular, with regard to the withdrawal of food and drink before surgery. 3. The use of chewing gum strongly reduced the incidence of nausea and vomiting. Therefore, it would be important to introduce, as a standard practice, this non-pharmacological prevention method in the postoperative period.
Synthesis and characterization of SmAlO3 by stearic acid route
Authors: Li J.M. , Zhang Chuimin , Liu Hui , Qiu Tai , Fan Chuangang 
Published: May 2020

Abstract
A rapid and facile approach was developed for the synthesis of ultrafine SmAlO3 powders through the combustion of stearic acid precursors. The obtained products were characterized by typical techniques including X-ray diffraction (XRD), Fourier Transform Infrared (FT-IR), thermogravimetric and differential thermal analysis (TG-DTA), scanning electron microscopy (SEM) and electron microscopy transmission (TEM) to analyze the phase composition and microstructure. The dielectric characteristics of SmAlO3 microwave ceramics, using the as-obtained products as original materials, were also studied. Compared with the conventional solid-state reaction method, the synthesis temperature was dramatically reduced to 750 ℃. The large-size sheet structure was composed of a number of micro/nano-scale crystallites, which were mostly irregular in shape due to the mutual growth and overlapping shapes of adjacent grains. The SmAlO3 ceramics with high density and uniform microstructure were obtained after sintering at 1500 ℃ for 4 h due to the favorable sintering activity of the as-synthesized powders. In addition, desired dielectric properties at microwave frequencies (dielectric constant εr = 20.22, quality factor Q·f = 74110 GHz, and a temperature coefficient of resonant frequency τf = -74.6 ppm/℃) were achieved.
Return-To-Practice Roadmap In Orthopedic Surgery Of A Spanish Military Hospital After Covid-19 Pandemic
Authors: Vita Diana Crego , Rodríguez-Moro Carlos , Gómez-Rico José Adolfo Orelana , García-Cañas Rafael , Martínez Monica Huecas , Herrero Azucena Martín , Jimenez Francisco Javier Areta 
Published: May 2020

Abstract
Background The impact of the COVID-19 pandemic In Spain, especially in Madrid, suddenly affected all the activity of the hospital including the suspension of all non-urgent surgical procedures. What´s more crucial, the urgent procedures were seriously obstructed by to factors: the mandatory protection measures (individual protection clothes, facemasks, and their initial stockout, etc), the redesigned flow of the patients in and out the operation room specially because the advisable diagnosis study of severe acute respiratory syndrome related Coronavirus 2 in each patient.Methods We review the patients treated in our orthopedic department during the outbreak of Coronavirus disease 19. Based in our early experience and the emergency situation with high contagious rate in Madrid, Spain, we have built a list of considerations and recommendations to guide orthopaedic units in their resumption of their regular activity, focusing at the moment of reintroduce elective surgeries, during the contained epidemic phases.Results The mortality rate in Coronavirus disease 19 patients was 3/9 and in the non Coronavirus disease group 4/23 developed pneumonia by Coronavirus2 (1 dead). There are no guidelines in literature for orthopedic surgeons in the postpandemic phase.Conclusion Coronavirus disease 19 patients have an elevated morbidity and mortality, surgery during this pandemia can facilitate pneumonia by Coronavirus2. The return-to-practice measures in the orthopedic units must take into account this fact. We recommend for each orthopedic surgery department to create a flowchart, as ours, in order to restart surgical activity.
The Mi-EFF1/Minc17998 effector interacts with the soybean GmHub6 protein to promote host plant parasitism by Meloidogyne incognita
Authors: Mendes Reneida Aparecida Godinho , Basso Marcos Fernando , de Melo Bruno Paes , Lima Rayane Nunes , de Araújo Janaina Fernandes , de-Sa Maira Grossi , Mattos Vanessa da Silva , Togawa Roberto Coiti , Albuquerque Érika Valéria Saliba , de-Sa Maria Eugênia Lisei , Silva Maria Cristina Mattar da , Macedo Leonardo Lima Pepino , Fragoso Rodrigo da Rocha , Fernandez Diana , Vignols Florence , Grossi-de-Sa Maria Fatima 
Published: May 2020

Abstract
The authors have requested that this preprint be removed from Research Square.
Identification of Mitochondrial DNA (NUMTs) in the Nuclear Genome of Daphnia Magna
Authors: Kowal Krzysztof , Tkaczyk Angelika , Pierzchała Mariusz , Bownik Adam , Ślaska Brygida 
Published: May 2020

Abstract
Background: This is the first study in which the Daphnia magna (D. magna) nuclear genome deposited in the GenBank data-base was analyzed for pseudogene sequences of mitochondrial origin. The first complete information about the genome of D. magna was published by Lee et al. in 2019. To date, there is no information about pseudogenes localized in the genome of D. magna . The aim of the present study was to identify NUMTs, their length, homology, and location for potential use in evolutionary studies and to check whether their occurrence causes co-amplification during mitochondrial genome analyses.Results: Bioinformatic analysis showed 1909 fragments of the mitochondrial genome of D. magna , of which 1630 fragments were located in ten linkage groups (LG) of the nuclear genome (nDNA). The most frequently occurring fragments of the mtDNA sequence in the nuclear genome included ND2 (115), ND3 (113), and TRNA-CYS (110)). However, the highest number of NUMTs was observed for the D-loop (147). 253 fragments showed 100% homology (from 16 to 46 bp) with mtDNA gene sequences. The sequence homology for TRNA-MET was 100% for all 6 NUMTs (from 16 to 18 bp). The overall length of NUMTs in the nDNA was 44.391 bp (from 16 to 182 bp), which accounted for 0.042% of the entire genome.Conclusions: The best-matched NUMTs covering more than 90% of the mtDNA gene sequence have been identified for the TRNA-ARG (95%), TRNA-GLU (97%), and TRNA-THR (95%) genes, and they may be included in the functional nuclear tRNA genes. Using the product of total DNA isolation in mtDNA studies, coamplification of nDNA fragments is unlikely in the case of amplification of the whole tRNA genes as well as fragments of other genes and the D-loop with a length exceeding 200 bp. It was observed that TRNA-MET fragments had the highest level of sequence homology, which means that they could be evolutionarily the youngest. The lowest degree of homology was found in the pseudogene derived from the mtDNA D-loop sequence. It may probably be the oldest element of mitochondrial DNA incorporated into the nuclear genome; however, further analysis is necessary.
Medicinal Plants Used in Four Local Government Areas of Southwestern Nigeria for the Management of Diabetes and Its Comorbidities: An Ethnobotanical Survey
Authors: Sidiq Latifat O. , Segun Peter A. , Ogbole Omonike O 
Published: May 2020

Abstract
Background:Diabetes mellitus (DM) continues to pose a major global health threat with serious economic burden in sub-Saharan Africa, especially Nigeria. This condition is often worsened with accompanying comorbidities, further putting a strain on patient wellbeing. Medicinal plants are not only effective in DM, but some of them are also have beneficial effects on accompanying disease states. Such plants may be appropriate alternatives or adjuncts to available antidiabetic medications. This study aimed at accessing and documenting the medicinal plants used in four local government of southwestern Nigeria for the management of diabetes and its comorbidities.Methods:Semi-structured questionnaires were used to obtain information from traditional medical practitioners, village elders and herb sellers. The data obtained were analyzed and discussed in relation to previously published literature. Fifty-three respondents mostly males (77.4%) provided information on medicinal plants useful for the management of diabetes and its comorbidities.Results:A total of 77 medicinal plants belonging to 76 genera in 44 plant families were mentioned in the survey. In particular, 53 medicinal plants are mentioned for managing diabetes, 35 for hypertension, 28 for stroke, 17 for heart diseases and 25 for obesity. The most frequently cited plant family was Leguminosae (12%), followed by Euphorbiaceae (8%). The frequently used plant species includesVernonia amygdalina, Citrus aurantifolia, Viscum album, Carica papaya, Allium sativum. It is interesting to note that only Citrus aurantifoliawas mentioned severally for the management of the five ailments. The herbal recipes, methods of herbal preparation and administration were also recorded.Conclusions:The survey shows that a significant number ofmedicinal plants are used for the management of diabetes and its comorbidities in the study area. These plants, apart from their hypoglycemic activity, may be useful against the most common complications of DM and may provide strategies for the development of less expensive therapies especially in low income communities.
Berbamine inhibits the infection of SARS-CoV-2 and flaviviruses by compromising TPRMLs-mediated endolysosomal trafficking of viral receptors
Authors: Huang Lihong , Li Huanan , Yuen Terrence Tsz-Tai , Ye Zuodong , Fu Qiang , Sun Wei , Xu Qiang , Yang Yang , Chan Jasper Fuk-Woo , Zhang Guoliang , Chu Hin , Qi Wenbao , Yue Jianbo 
Published: May 2020

Abstract
Positive-sense single-stranded ((+)ss) RNA viruses are among the leading causes of human and animal infectious diseases in the world, but so far, no effective antiviral agents are available to treat these infections. Here we found that several bis- benzylisoquinoline alkaloids (e.g. berbamine), potently inhibited the infection of coronaviruses (e.g. SARS-CoV-2 and MERS-CoV), flaviviruses (e.g. JEV, ZIKV and DENV), and enteroviruses (e.g. EV-A71) in host cells. Moreover, berbamine protected mice from lethal challenge of JEV. We also found that berbamine inhibited TRPMLs (Ca2+ permeable non-selective cation channels in endosomes and lysosomes), which compromised the endolysosomal trafficking of viral receptors, such as ACE2 and DPP4. This led to the increased secretion of these receptors via extracellular vesicles and the concomitant decrease in their levels at the plasma membrane, thereby preventing (+)ss RNA viruses from entering the host cells. In summary, these results indicate that bis- benzylisoquinoline alkaloids such as berbamine, can act as a pan-anti-(+)ss RNA virus drug by inhibiting TPRMLs to prevent viral entry.
Neurological Involvement of Coronavirus Disease 2019: A Systematic Review
Authors: Ghannam Malik , Alshaer Qasem , Al-Chalabi Mustafa , Zakarna Lara , Robertson Jetter , Manousakis Georgios 
Published: May 2020

Abstract
Background: In December 2019, unexplained cases of pneumonia emerged in Wuhan, China, which were found to be secondary to the novel coronavirus SARS-CoV-2. On March 11, 2020, the WHO declared the Coronavirus Disease 2019 (COVID-2019) outbreak, a pandemic. Although the most common presentations of COVID-19 are fever, cough and shortness of breath, several clinical observations indicate that COVID-19 does affect the central and peripheral nervous system. Methods: We conducted a systematic literature search from December 01, 2019 to May 14, 2020 using multiple combinations of keywords from PubMed and Ovid Medline databases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We included articles with cases of COVID-19 that were evident for neurological involvement. Results: We were able to identify 82 cases of COVID-19 with neurological complications. The mean age was 62.28 years. 37.8% of the patients were women (n = 31). 48.8% of the patients (n=40) had cerebrovascular insults, 28% (n=23) had neuromuscular disorders, 18.3% of the patients (n=15) had encephalitis or encephalopathy, and 2.4% (n=2) presented with status epilepticus. Conclusions: Neurological manifestations of COVID-19 infection are not rare, especially large vessel stroke, Guillain barre syndrome and meningoencephalitis. Moving forward, further studies are needed to clarify the prevalence of the neurological complications of COVID-19, investigate their biological backgrounds, and test treatment options. Physicians should be cautious not to overlook other neurological diagnoses that can mimic COVID-19 during the pandemic.
TÜRKİYEDE HELİKOPTER EBEVEYNLİK EĞİLİMİ VE HELİKOPTER EBEVEYNLERİN DEMOGRAFİK ÖZELLİKLERİ
Authors: YILMAZ Hasan 
Published: May 2020

Çocuklarını
yetiştirmede tutarsız bir otoriterlik ve aşırı korumacılık karışımıyla bilinen
helikopter ebeveynlik tarzı; çocuğun yaşından bağımsız olarak onları kontrol
etme ihtiyacı, onlara özerklik vermeme veya sınırlandırma, çocuklarını
gerçekten sevmedikleri etkinlikleri yapmaya zorlama, farklı konularda ders
aldırma veya başkalarıyla sosyalleşmesinden mahrum etme, akademik sonuçları her
şeyden önemli ve öncelikli tutma, çocuklarının yaptıkları her şeyde haklı
olduklarını düşünme eğilimi, okul öncesinden üniversiteye kadar her kademede öğretmen
ve okul kurullarından sürekli olarak şikayette bulunma davranışlarıyla
karakterize bir çocuk yetiştirme yaklaşımıdır.

Yapılan
araştırmanın amacı Türkiye’de helikopter ebeveynliğin yaygınlığını hem anne hem
baba boyutunda ortaya koymaktır. Bu gelen amaç çerçevesinde anne babaların
hangi konularda helikopter ebeveyn tutumlarının daha baskın olduğunun; yaş,
cinsiyet, eğitim düzeyi, yerleşim yerinin özelliği gibi demografik değişkenlere
göre tespit edilmesi hedeflenmiştir.
Araştırmada betimsel tarama yöntemi kullanılmıştır. Bu amaçla Yaşları 11
ile 22 arasında değişen ve ortaokul ile lisans üstü eğitim seviyelerinde
öğrenim gören 1600 kişiye Algılanan Helikopter Ebeveyn ölçeği uygulanmıştır. Ebeveynlerinin
tutumunu helikopter olarak algılayan 666 katılımcının verileri üzerinde de
tanımlayıcı istatistik değerleri, varyans analizi, t testi ve Scheffe test
yöntemleri ile analizler yapılmıştır.

Araştırmanın
sonunda, Türkiye’de annelerin üçte birinin, babaların ise yedide birinin
helikopter ebeveyn tutuma sahip olduğu, annelerin babalara kıyasla daha fazla
helikopter tutum sergiledikleri gözlenmiştir. Ortaokulda öğrenci olan katılımcıların
algıladıkları helikopter ebeveyn tutumları, diğer eğitim kademelerindeki
katılımcılardan yüksek bulunmuştur. Tek çocuklu, büyük şehirlerde yaşayan
ebeveynlerde helikopter tutum daha fazla gözlenirken helikopter ebeveyn
tutumunun çocukların cinsiyetinden etkilenmediğini de saptanmıştır.
Development of Reverse Phase Ultra-fast Liquid Chromatography Using Ion-pairing Reagent for Quantitative Assessment of Ceftriaxone in Rat Serum and Cerebrospinal Fluid
Authors: Padhi Swarupanjali , Mazumder Rupa , Bisth Shradha 
Published: May 2020

Background:In case of meningitis, the meninges are inflamed and the blood brain barrier is
distorted, therefore, there is no hindrance to drug penetration. The problem arises when the disease is at
the verge of cure, the meninges become uninflamed and the permeability of the drug is reduced to such
extend that it becomes nearly impossible to maintain the minimum inhibitory concentration of drug at
the site of infection. This problem was overcome by formulating ceftriaxone loaded NLCs and administrating
it through intraperitoneal route to Wistar Albino rat. For quantitative assessment of drugs in
rat serum and cerebrospinal spinal fluid, a new RP-UFLC (reverse-phase ultra-fast liquid chromatography)
method has been developed and validated.

Objective:Development and validation of RP-UFLC (using ion-pairing reagent) method for accurate
estimation of ceftriaxone in rat serum and CSF.

Methods:Method validation is done according to the ICH Guidelines (Q2) for the estimation of ceftriaxone
in rat serum and its CSF (cerebrospinal fluid) by the RP-UFLC method. The blood was collected
from the rat tail vein and CSF was collected carefully from cisterna magna of the rats by a 23G syringe.
The mobile phase was used in a ratio of 70:30%v/v of phosphate buffer with ion-pairing reagent and
acetonitrile with a pH of 8.0

Results:Limit of detection and limit of quantification of ceftriaxone in rat serum was 1.08 μg/ml and
3.84 μg/ml, respectively. Similarly, the limit of detection and limit of quantification of ceftriaxone in
CSF of rats was 0.94 μg/ml and 2.84 μg/ml, respectively. In both cases, the R2 value was more than
0.99 and showed 99% accuracy.

Conclusion:The experimental result suggests that the new RP-UFLC method developed and
validated can be effectively used to assess ceftriaxone in preclinical studies in rats.