bluuebunny/crossref_metadata_2025_split huggingface dataset:
How will southern hemisphere subtropical anticyclones respond to global warming? Mechanisms and seasonality in CMIP5 and CMIP6 model projections
Authors: Fahad Abdullah al , Burls Natalie J. , Strasberg Zachary 
Published: May 2020

AbstractThe anticyclonic high-pressure systems over the southern-hemisphere, subtropical oceans have a significant influence on regional climate. Previous studies of how these subtropical anticyclones will change under global warming have focused on austral summer while the winter season has remained largely uninvestigated, together with the extent to which the dominant mechanisms proposed to explain the multi-model-mean changes similarly explain the inter-model spread in projections. This study addresses these gaps by focusing on the mechanisms that drive the spread in projected future changes across the Coupled Model Intercomparison Project Phase 5 and 6 archives during both the summer and winter seasons. The southern hemisphere anticyclones intensify in strength at their center and poleward flank during both seasons in the future projections analyzed. The inter-model spread in projected local diabatic heating changes accounts for a considerable amount of the inter-model spread in the response of the South Pacific anticyclone during both seasons. However, model differences in projected zonal-mean tropospheric static stability changes, which in turn influence baroclinic eddy growth, are most influential in determining the often-strong increases in sea level pressure seen along the poleward flank of all the anticyclones during both seasons. Increased zonal-mean tropospheric static stability over the subtropics is consistent with the poleward shift in Hadley cell edge and zonal-mean sea level pressure increases. The results suggest that differences in the extent of tropical-upper-tropospheric and subtropical-lower-tropospheric warming in the southern hemisphere, via their influence on tropospheric static stability, will largely determine the fate of the anticyclones over the coming century.
Vitamin D and the hepatitis B vaccine response: a prospective cohort study and a randomized, placebo-controlled oral vitamin D3 and simulated sunlight supplementation trial in healthy adults
Authors: Kashi Daniel S. , Oliver Samuel J. , Wentz Laurel M. , Roberts Ross , Carswell Alexander T. , Tang Jonathan C. Y. , Jackson Sarah , Izard Rachel M. , Allan Donald , Rhodes Lesley E. , Fraser William D. , Greeves Julie P. , Walsh Neil P. 
Published: May 2020

Abstract
Purpose
To determine serum 25(OH)D and 1,25(OH)2D relationship with hepatitis B vaccination (study 1). Then, to investigate the effects on hepatitis B vaccination of achieving vitamin D sufficiency (serum 25(OH)D ≥ 50 nmol/L) by a unique comparison of simulated sunlight and oral vitamin D3 supplementation in wintertime (study 2).

Methods
Study 1 involved 447 adults. In study 2, 3 days after the initial hepatitis B vaccination, 119 men received either placebo, simulated sunlight (1.3 × standard-erythema dose, 3 × /week for 4 weeks and then 1 × /week for 8 weeks) or oral vitamin D3 (1000 IU/day for 4 weeks and 400 IU/day for 8 weeks). We measured hepatitis B vaccination efficacy as percentage of responders with anti-hepatitis B surface antigen immunoglobulin G ≥ 10 mIU/mL.

Results
In study 1, vaccine response was poorer in persons with low vitamin D status (25(OH)D ≤ 40 vs 41–71 nmol/L mean difference [95% confidence interval] − 15% [− 26, − 3%]; 1,25(OH)2D ≤ 120 vs ≥ 157 pmol/L − 12% [− 24%, − 1%]). Vaccine response was also poorer in winter than summer (− 18% [− 31%, − 3%]), when serum 25(OH)D and 1,25(OH)2D were at seasonal nadirs, and 81% of persons had serum 25(OH)D < 50 nmol/L. In study 2, vitamin D supplementation strategies were similarly effective in achieving vitamin D sufficiency from the winter vitamin D nadir in almost all (~ 95%); however, the supplementation beginning 3 days after the initial vaccination did not effect the vaccine response (vitamin D vs placebo 4% [− 21%, 14%]).

Conclusion
Low vitamin D status at initial vaccination was associated with poorer hepatitis B vaccine response (study 1); however, vitamin D supplementation commencing 3 days after vaccination (study 2) did not influence the vaccination response.

Clinical trial registry number
Study 1 NCT02416895; https://clinicaltrials.gov/ct2/show/study/NCT02416895; Study 2 NCT03132103; https://clinicaltrials.gov/ct2/show/NCT03132103.
Impact of intracellular hemin on N-type inactivation of voltage-gated K+ channels
Authors: Coburger Ina , Yang Kefan , Bernert Alisa , Wiesel Eric , Sahoo Nirakar , Swain Sandip M. , Hoshi Toshinori , Schönherr Roland , Heinemann Stefan H. 
Published: May 2020

AbstractN-type inactivation of voltage-gated K+channels is conferred by the N-terminal “ball” domains of select pore-forming α subunits or of auxiliary β subunits, and influences electrical cellular excitability. Here, we show that hemin impairs inactivation of K+channels formed by Kv3.4 α subunits as well as that induced by the subunits Kvβ1.1, Kvβ1.2, and Kvβ3.1 when coexpressed with α subunits of the Kv1 subfamily. In Kvβ1.1, hemin interacts with cysteine and histidine residues in the N terminus (C7 and H10) with high affinity (EC50100 nM). Similarly, rapid inactivation of Kv4.2 channels induced by the dipeptidyl peptidase-like protein DPP6a is also sensitive to hemin, and the DPP6a mutation C13S eliminates this dependence. The results suggest a common mechanism for a dynamic regulation of Kv channel inactivation by heme/hemin in N-terminal ball domains of Kv α and auxiliary β subunits. Free intracellular heme therefore has the potential to regulate cellular excitability via modulation of Kv channel inactivation.
Yes, I can - maybe … Effects of placebo-related instructions on neuroregulation in children with ADHD
Authors: Gevensleben Holger , Schmiedeke David , Heinrich Hartmut , Rothenberger Aribert 
Published: May 2020

AbstractNeurofeedback training (NFT) provides strategies for children with ADHD to achieve changes on the neurophysiological and behavioral level to attenuate ADHD symptoms. We assume self-efficacy (an “active attitude”), a core variable in successful NFT. In a randomized, double-blind controlled study, we investigated the impact of a “placebo instruction” on the EEG-regulation performance during two sessions of Theta-Beta-NFT in children with ADHD (age 8–12 years). Children receiving the information “this might be a placebo-training” showed inferior neuroregulation (n = 10) compared to children receiving a standard instruction (n = 12). Results of our pilot study are discussed in view of factors necessary for a valid training (ensuring maximal self-efficacy in the participants) and the fidelity of placebo-controlled trials in NFT-research.
A randomized, controlled, two-month pilot trial of stannous fluoride dentifrice versus sodium fluoride dentifrice after oxalate treatment for dentinal hypersensitivity
Authors: Anderson Chad J. , Kugel Gerard , Zou Yuanshu , Ferrari Marco , Gerlach Robert 
Published: May 2020

Abstract
Objectives
To compare the effects of a stannous fluoride dentifrice and a sodium fluoride dentifrice on dentinal hypersensitivity when used with an oxalate-based regimen combining in-office and at-home treatment.

Materials and methods
In this single-center, randomized, controlled, double-blind, pilot clinical trial, 30 subjects were professionally treated at baseline with a 3% oxalate/potassium salt solution on up to two target teeth, then randomized 1:1 to either 0.454% stannous fluoride or 0.243% sodium fluoride overlabeled dentifrice. Both groups were given 6 sensitivity strips (3.14% potassium oxalate gel) and a soft, manual toothbrush. Subjects were permitted to apply strips on up to two teeth, up to three times per tooth, at home as desired throughout the study. Dentinal sensitivity (cold air blast challenge) was assessed at baseline, immediately after post-professional treatment, and at day 60 using the Schiff scale and a Visual Analog Scale (VAS).

Results
Immediately after professional oxalate treatment, the overall mean Schiff and VAS score decreased 25.6% and 22.4% from baseline, respectively (p ≤ 0.001 for both). At day 60, further reductions in both mean scores were seen in both groups. There were no significant differences between the groups at day 60. All treatments were well tolerated.

Conclusions
In subjects treated with oxalates for dentinal hypersensitivity, both stannous fluoride and sodium fluoride dentifrices are well tolerated, are feasible for routine use, and do not detract from the desensitizing effects of an in-office and at-home oxalate combination treatment regimen.

Clinical relevance
Either stannous fluoride or sodium fluoride dentifrices can be recommended to dentinal hypersensitivity patients who undergo professional oxalate treatment.
Soil organic matter relationships with the geotechnical-hydrological parameters, mineralogy and vegetation cover of hillslope deposits in Tuscany (Italy)
Authors: Masi Elena Benedetta , Bicocchi Gabriele , Catani Filippo 
Published: May 2020

AbstractSoil organic matter (SOM) represents a main fraction of superficial soil characterized by a mechanical-hydrological behaviour different from that of the inorganic fractions. In this study, a method to measure the SOM content was applied to 27 selected sites in Tuscany (central Italy) characterized by the presence of soil types common in the region: cambisols and regosols. The method included the contribution from root fragments, which is a fraction often neglected or underestimated in measurements, in the overall estimate of the SOM content. The retrieved SOM contents were analysed considering the vegetation cover at the sites and the selected attributes of geological interest, such as geotechnical parameters and the mineralogical composition of the soils. The SOM normalized to the bulk samples ranges between 1.8 and 8.9% by weight, with the highest values of the SOM content being associated with vegetation cover classes of forest and woodlands without shrubs. The SOM values showed close relationships with the abundance of the finer fractions (silt and clay) of the soil samples, and considering the relations with geotechnical properties, moderate correlations were found with the plasticity index, unit weight and effective friction angle, overall demonstrating the importance of considering SOM when the geotechnical and hydrological properties of soils are evaluated.
The Sustainable Development Goals prioritize economic growth over sustainable resource use: a critical reflection on the SDGs from a socio-ecological perspective
Authors: Eisenmenger Nina , Pichler Melanie , Krenmayr Nora , Noll Dominik , Plank Barbara , Schalmann Ekaterina , Wandl Marie-Theres , Gingrich Simone 
Published: May 2020

AbstractThe sustainable development goals (SDGs) were adopted in 2015, succeeding the Millennium Development Goals (MDGs). While the MDGs focused on improving well-being in the developing world, the 17 SDGs address all countries and aim at reconciling economic and social with ecological goals. We adopt a social ecology perspective and critically reflect on the SDGs’ potential for monitoring, supporting, and bringing about a transformation towards sustainability. Starting from a literature review on the SDGs, we link empirical findings from social ecology with analyses of SDG targets and indicators. First, we find that the SDGs fail to monitor absolute trends in resource use and thus prioritize economic growth over ecological integrity. Second, we discuss the contradictions between economic growth and sustainable resource use in early and late stages of industrialization processes and show that they are responsible for important trade-offs among SDG targets. Third, we analyze the transformative potential of the SDGs with a focus on the actors and institutions addressed to bring about transformative change. We find that the SDGs rely mainly on those institutions responsible for unsustainable resource use, and partly propose measures that even reinforce current trends towards less sustainability. Despite ascertaining limited transformative potential to the SDGs from an analytical perspective, we conclude by stressing the strategic relevance of the SDGs for visions, research, and practices of statt towards transformative change towards sustainability.
What limits the efficacy of coercion?
Authors: Schøyen Øivind 
Published: May 2020

AbstractWe model a game between an authority, seeking to implement its state identity, and a parental generation, seeking to socialize a younger generation into their own identity. The authority first selects a coercion level against the non-state identity. The parental generation then chooses whether to insurrect in response to the coercion level and, if not, decides how much to invest in socializing their children into the non-state identity. In this overlapping generations model, we formalize and explore the consequences of an intrinsic negative reaction to coercion: coercion resentment. We show how coercion resentment can create an interval where coercion has negative efficacy in imposing the state identity. This causes the rational legitimacy maximizing authority to restrain its use of coercion. We then show how this inefficacy of coercion can make certain levels of coercion unimplementable without causing the non-state identity to insurrect. This causes the long-run equilibrium size of the non-state identity group to be dependent on their initial size and, thus, path dependence. We consider the validity of the model by reviewing two historical episodes: Stalin’s secularization project (1922–1953) and the Counter-Reformation in early modern France and the Holy Roman Empire (1517–1685).
The Brain Retains: Nonhuman Primate Models for Pediatric HIV-1 in the CNS
Authors: Obregon-Perko Veronica , Bricker Katherine , Chahroudi Ann 
Published: May 2020

Abstract
Purpose of Review
Perinatal HIV-1 infection is associated with an increased risk for neurologic impairments. With limited access to clinical specimens, animal models could advance our understanding of pediatric central nervous system (CNS) disease and viral persistence. Here, we summarize current findings on HIV-1 CNS infection from nonhuman primate (NHP) models and discuss their implications for improving pediatric clinical outcomes.

Recent Findings
SIV/SHIV can be found in the CNS of infant macaques within 48 h of challenge. Recent studies show an impermeable BBB during SIV infection, suggesting neuroinvasion in post-partum infection is likely not wholly attributed to barrier dysfunction. Histopathological findings reveal dramatic reductions in hippocampal neuronal populations and myelination in infected infant macaques, providing a link for cognitive impairments seen in pediatric cases. Evidence from humans and NHPs support the CNS as a functional latent reservoir, harbored in myeloid cells that may require unique eradication strategies.

Summary
Studies in NHP models are uncovering early events, causes, and therapeutic targets of CNS disease as well as highlighting the importance of age-specific studies that capture the distinct features of pediatric HIV-1 infection.
Hand Tuberculosis: a Common Disease at an Uncommon Site
Authors: Tendulkar Sushrut , Shivaprakash Shashikala , Gandhi Bhupendra , Jain Paresh 
Published: May 2020

AbstractTuberculosis (TB) is one of the major health problems in developing countries. India has the highest TB burden with approximately 27% of global TB [6]. (India TB Report 2018 Revised National TB Control Programme (2018)). The most common form of tuberculosis constitutes pulmonary tuberculosis. Among extra pulmonary tuberculosis, the musculoskeletal tuberculosis accounts for about 10–15% cases (Mohd Altaf Mir, Imran Ahmad, Mihd Yaseen (2016) World J Plast Surg 5(3):313–318). Hand involvement is seen in 10% of patients with musculoskeletal disease. There has been recent interest in tuberculosis of the hand because of a rising incidence owing to increasing numbers of immigration, an aging population, and immunosuppressed people including affected patients with human immunodeficiency virus [3,7] (Centre for Disease Control (1995) MMWR 14:1–16), Al-Qattan MM, Al-Namla A, Al-Thunayan A, Al-Omawi M (2011) J Hand Surg 36:1413–1422). Tuberculous tenosynovial disease (TBTS) is the most common presentation of hand tuberculosis. In the hand, the flexor tendon sheath and radio-ulnar bursae are the most common sites of tenosynovitis. Tuberculosis of hand is more commonly seen in the dominant hand of the male population (Al-Qattan MM, Al-Namla A, Al-Thunayan A, Al-Omawi M (2011) J Hand Surg 36:1413–1422). Here, we present a case of TBTS affecting extensor compartment of dominant hand in a post renal transplant immunosuppressed individual.
Goal-oriented error estimation and mesh adaptation for shallow water modelling
Authors: Wallwork Joseph G. , Barral Nicolas , Kramer Stephan C. , Ham David A. , Piggott Matthew D. 
Published: May 2020

AbstractThis study presents a novel goal-oriented error estimate for the nonlinear shallow water equations solved using a mixed discontinuous/continuous Galerkin approach. This error estimator takes account of the discontinuities in the discrete solution and is used to drive two metric-based mesh adaptation algorithms: one which yields isotropic meshes and another which yields anisotropic meshes. An implementation of these goal-oriented mesh adaptation algorithms is described, including a method for approximating the adjoint error term which arises in the error estimate. Results are presented for simulations of two model tidal farm configurations computed using the Thetis coastal ocean model (Kärnä et al. in Geosci Model Dev 11(11):4359–4382, 2018). Convergence analysis indicates that meshes resulting from the goal-oriented adaptation strategies permit accurate QoI estimation using fewer computational resources than uniform refinement.
Defining racial and ethnic context with geolocation data
Authors: Moore Ryan T. , Reeves Andrew 
Published: May 2020

AbstractAcross disciplines, scholars strive to better understand individuals’ milieus—the people, places, and institutions individuals encounter in their daily lives. In particular, political scientists argue that racial and ethnic context shapes attitudes about candidates, policies, and fellow citizens. Yet, the current standard of measuring milieus is to place survey respondents in a geographic container and then to ascribe all that container's characteristics to the individual's milieu. Using a new dataset of over 2.6 million GPS records from over 400 individuals, we compare conventional static measures of racial and ethnic context to dynamic, precise measures of milieus. We demonstrate how low-level static measures tend to overstate how extreme individuals’ racial and ethnic contexts are and offer suggestions for future researchers.
ON THE PRODUCT OF ELEMENTS WITH PRESCRIBED TRACE
Authors: SHEEKEY JOHN , VAN DE VOORDE GEERTRUI , VOLOCH JOSÉ FELIPE 
Published: May 2020

AbstractThis paper deals with the following problem. Given a finite extension of fields $\mathbb{L}/\mathbb{K}$ and denoting the trace map from $\mathbb{L}$ to $\mathbb{K}$ by $\text{Tr}$, for which elements $z$ in $\mathbb{L}$, and $a$, $b$ in $\mathbb{K}$, is it possible to write $z$ as a product $xy$, where $x,y\in \mathbb{L}$ with $\text{Tr}(x)=a,\text{Tr}(y)=b$? We solve most of these problems for finite fields, with a complete solution when the degree of the extension is at least 5. We also have results for arbitrary fields and extensions of degrees 2, 3 or 4. We then apply our results to the study of perfect nonlinear functions, semifields, irreducible polynomials with prescribed coefficients, and a problem from finite geometry concerning the existence of certain disjoint linear sets.
Satellite galaxies as better tracers of the Milky Way halo mass
Authors: Han Jiaxin , Wang Wenting , Li Zhaozhou 
Published: May 2020

AbstractThe inference of the Milky Way halo mass requires modelling the phase space structure of dynamical tracers, with different tracers following different models and having different levels of sensitivity to the halo mass. For steady-state models, deviations from steady-state in the tracer distribution lead to an irreducible stochastic bias. This bias is small for satellite galaxies and dark matter particles, but as large as a factor of 2 for halo stars. This is consistent with the picture that satellite galaxies closely trace the underlying phase space distribution of dark matter particles, while halo stars are less phase-mixed. As a result, the use of only ~100 satellite galaxies can achieve a significantly higher accuracy than that achievable with a much larger sample of halo stars.
Dynamical modelling of brightest cluster galaxies: Constraints on the IMF
Authors: Loubser S. I. 
Published: May 2020

AbstractWe study the stellar and dynamical masses, as well as the stellar populations, of brightest cluster galaxies (BCGs) located in 32 massive clusters, and for a sub-sample of these use the results to place constraints on the Initial Mass Function (IMF). We measure the spatially-resolved stellar population properties of the BCGs, such as recent star formation episodes, and use it to predict their stellar mass-to-light ratios (ϒ*POP). We find that ∼60 per cent of the BCGs have constant ϒ*POP over the radial range (<15 kpc). We also use the stellar and dynamical mass profiles to derive the stellar mass-to-light ratio from dynamics (ϒ*DYN, see Loubser, these proceedings). We directly compare ϒ*POP with ϒ*DYN, and find that for most BCGs, a Salpeter IMF is needed to explain their properties, but we also find a small subset of BCGs for which a Kroupa-like IMF is needed to explain their properties.
Coevolution (or not) of supermassive black holes and host galaxies: Black hole scaling relations are not biased by selection effects
Authors: Kormendy John 
Published: May 2020

AbstractThe oral version of this paper summarized Kormendy & Ho 2013, ARA&A, 51, 511. However, earlier speakers at this Symposium worried that selection effects bias the derivation of black hole scaling relations. I therefore added – and this proceedings paper emphasizes – a discussion of why we can be confident that selection effects do not bias the observed correlations between BH mass M• and the luminosity, stellar mass, and velocity dispersion of host ellipticals and classical bulges. These are the only galaxy components that show tight BH-host correlations. The scatter plots of M• with host properties for pseudobulges and disks are upper envelopes of scatter that does extend to lower BH masses. BH correlations are most consistent with a picture in which BHs coevolve only with classical bulges and ellipticals. Four physical regimes of coevolution (or not) are suggested by Kormendy & Ho 2013 and are summarized here.
Streams and the Milky Way dark matter halo
Authors: Newberg Heidi Jo , Shelton Siddhartha , Mendelsohn Eric , Weiss Jake , Arsenault Matthew , Bauer Jacob S. , Desell Travis , Judd Roland , Magdon-Ismail Malik , Newberg Lee A. , Newby Matthew , Rayment Clayton , Rice Colin , Szymanski Boleslaw K. , Thompson Jeffery M. , Ulin Steve , Varela Carlos , Widrow Lawrence M. , Willett Benjamin A. 
Published: May 2020

AbstractWe describe an algorithm that can fit the properties of the dwarf galaxy progenitor of a tidal stream, given the properties of that stream. We show that under ideal conditions (the Milky Way potential, the orbit of the dwarf galaxy progenitor, and the functional form of the dwarf galaxy progenitor are known exactly), the density and angular width of stars along the stream can be used to constrain the mass and radial profile of both the stellar and dark matter components of the progenitor dwarf galaxy that was ripped apart to create the stream. Our provisional fit for the parameters of the dwarf galaxy progenitor of the Orphan Stream indicates that it is less massive and has fewer stars than previous works have indicated.