bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modified Lupaş-Jain operators
Authors: Bodur Murat 
Published: March 2020

Abstract
The goal of this paper is to propose a modification of Lupaş-Jain operators based on a function ρ having some properties. Primarily, the convergence of given operators in weighted spaces is discussed. Then, order of approximation via weighted modulus of continuity is computed for these operators. Further, Voronovskaya type theorem in quantitative form is taken into consideration, as well. Ultimately, some graphical results that illustrate the convergence of investigated operators to f are given.
Scrutiny of some fixed point results by S-operators without triangular inequality
Authors: Khojasteh Farshid , Khandani Hassan 
Published: March 2020

Abstract
In this work, the discussion centers on introducing non-triangular metric as a generalization of JS-metric, which may lessen the frantic pace of working on generalizing the triangle inequality by omitting it from the original ordinary metric’s definition. Then, we present S-operators as a new sort of mappings included some properties in order to characterize some known contractions. After that, we graft non-triangular metric onto S-operators in order to make the worthwhile fixed point results facile to prove and conceive.
Agenda-setting and Public Policy in Private Foundations
Authors: Williamson Alexandra Kate , Luke Belinda 
Published: March 2020

AbstractThis paper examines advocacy, agenda-setting and the public policy focus of private philanthropic foundations in Australia. While concerns have been raised regarding advocacy and public policy influence of foundations in countries such as the U.S., less is understood on this issue in other contexts. Interviews were conducted with 11 managers and trustees of 10 Private Ancillary Funds (PAFs) in late 2014. Analysis of publicly available data on the participating PAFs was then undertaken comparing PAF information available at the time of the interviews with that available approximately five years later, to consider any changes in the public communication of their agendas. Findings reveal PAFs’ agendas were largely consistent with public policy but may vary in the approaches to address social causes. Further, a preference for privacy indicates the PAF sector may be characterised as ‘quiet philanthropy’ rather than having a visible public presence. As such, PAFs’ advocacy focused on promoting philanthropy, rather than altering or influencing public policy. Our main contention is that the conceptions of advocacy in structured philanthropy are dominated by the obvious, the outliers and the noisy. Our contribution to the philanthropic literature is a more nuanced and broader discussion of how advocacy and agenda-setting occurs and is understood in the mainstream.
Giving Voice beyond Her Vote: How Women Used Charitable Giving to Create Social Change after the 2016 U.S. Presidential Election
Authors: Mesch Debra J. , Osili Una O. , Bergdoll Jonathan J. , Skidmore Tessa B. , Ackerman Jacqueline E. L. , Han Xiao 
Published: March 2020

Abstract
This study fills a gap in research on the philanthropic outcomes of political events. More specifically, it provides empirical evidence to supplement anecdotal reports that nonprofit organizations experienced a substantial increase in donations following the 2016 U.S. presidential election. Based on daily transaction data from an online giving platform, the study uses random-effect panel Ordinary Least Squares models to examine whether and how charitable giving patterns changed after Election Day 2016. Overall, our analyses show no evidence of increased giving due to the election; however, gender differences are apparent. Women donated in greater amounts than men following Election Day, and they appear to have targeted relevant progressive charities with their giving.
Histórias de Ultramar: Antecedentes e proclamação da Primeira Cruzada. O caminho e a conquista de Jerusalém.
Authors: Costalonga Jeferson Dalfior 
Published: March 2020

Poucas obras na história se tornaram tão indispensáveis para a compreensão de determinados temas como Historias de Ultramar para análises acerca das cruzadas. Este trabalho se faz presente na bibliografia de qualquer livro que se propõe abordar o referido assunto.
Topoisomerases Modulate the Timing of Meiotic DNA Breakage and Chromosome Morphogenesis inSaccharomyces cerevisiae
Authors: Heldrich Jonna , Sun Xiaoji , Vale-Silva Luis A , Markowitz Tovah E , Hochwagen Andreas 
Published: March 2020

AbstractMeiotic chromosomes experience substantial strain due to morphological changes and ongoing metabolism of the DNA. Outside of meiosis, topology-modifying enzymes called topoisomerases manage this sort of strain, but their function during meiotic prophase has not been thoroughly explored...During meiotic prophase, concurrent transcription, recombination, and chromosome synapsis place substantial topological strain on chromosomal DNA, but the role of topoisomerases in this context remains poorly defined. Here, we analyzed the roles of topoisomerases I and II (Top1 and Top2) during meiotic prophase in Saccharomyces cerevisiae. We show that both topoisomerases accumulate primarily in promoter-containing intergenic regions of actively transcribing genes, including many meiotic double-strand break (DSB) hotspots. Despite the comparable binding patterns, top1 and top2 mutations have different effects on meiotic recombination. TOP1 disruption delays DSB induction and shortens the window of DSB accumulation by an unknown mechanism. By contrast, temperature-sensitive top2-1 mutants exhibit a marked delay in meiotic chromosome remodeling and elevated DSB signals on synapsed chromosomes. The problems in chromosome remodeling were linked to altered Top2 binding patterns rather than a loss of Top2 catalytic activity, and stemmed from a defect in recruiting the chromosome remodeler Pch2/TRIP13 to synapsed chromosomes. No chromosomal defects were observed in the absence of TOP1. Our results imply independent roles for Top1 and Top2 in modulating meiotic chromosome structure and recombination.
EMA Recommendation for the Pediatric Indications of Plerixafor (Mozobil) to Enhance Mobilization of Hematopoietic Stem Cells for Collection and Subsequent Autologous Transplantation in Children with Lymphoma or Malignant Solid Tumors
Authors: Karres Dominik , Ali Sahra , van Hennik Paula B. , Straus Sabine , Josephson Filip , Thole Geanne , Glerum Pieter J. , Herberts Carla , Babae Negar , Herold Ralf , Papadouli Irene , Pignatti Francesco 
Published: March 2020

Abstract

On March 28, 2019, the Committee for Medicinal Products for Human Use adopted a positive opinion recommending the marketing authorization for the medicinal product plerixafor. The marketing authorization holder for this medicinal product is Genzyme Europe B.Th. The adoption was for an extension of the existing adult indication in combination with granulocyte colony-stimulating factor (G-CSF) to pediatric patients (aged 1 year to &lt;18 years) to enhance mobilization of hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in children with lymphoma or solid malignant tumors. This treatment is indicated either preemptively, when circulating stem cell count on the predicted day of collection after adequate mobilization with G-CSF (with or without chemotherapy) is expected to be insufficient with regard to desired hematopoietic stem cells yield, or in children who previously failed to collect sufficient hematopoietic stem cells.
The efficacy and safety of plerixafor were evaluated in an open label, multicenter, phase I/II, dose-ranging, and randomized controlled study (DFI12860) in pediatric patients with solid tumors, including neuroblastoma, sarcoma, Ewing sarcoma, or lymphoma, who were eligible for autologous hematopoietic stem cell transplantation. Forty-five patients (aged 1 year to &lt;18 years) were randomized, 2:1, using 0.24 mg/kg of plerixafor plus standard mobilization (G-CSF with or without chemotherapy) versus control (standard mobilization alone). The primary analysis showed that 80% of patients in the plerixafor arm experienced at least a doubling of the peripheral blood (PB) CD34+ count, observed from the morning of the day preceding the first planned apheresis to the morning prior to apheresis, versus 28.6% of patients in the control arm (p = .0019). The median increase in PB CD34+ cell counts from baseline to the day of apheresis was 3.2-fold in the plerixafor arm versus by 1.4-fold in the control arm.
The observed safety profile in the pediatric population was consistent with that in adults, with adverse events mainly related to injection site reactions, hypokalemia, and increased blood bicarbonate. Importantly, plerixafor exposure did not seem to negatively affect transplant efficiency. This article summarizes the scientific review of the application leading to regulatory approval in the European Union.

Implications for Practice
This review of the marketing authorization of plerixafor will raise awareness of pediatric indication granted for this medicinal product.
ÖĞRETMEN VE ÖĞRENCİ GÖZÜNDEN BİR EV ÖDEVİ PORTRESİ
Authors: ALPAYAR Cagla 
Published: March 2020

Bu araştırmada,
tipik ev ödevi uygulamalarının yürütüldüğü ilkokul dördüncü sınıftaki ev ödevi
portresinin ortaya konması amaçlanmaktadır. Bu amaca yönelik olarak, öğretmenin
Trafik Güvenliği dersinde verilen üç farklı türdeki ödevden beklentilerinin ne
olduğu ve bu beklentilerin öğrencilerde karşılığını bulup bulmadığı
araştırılmıştır. Bu nedenle de araştırma nitel araştırma deseninde yürütülmüştür.
Katılımcılar, İç Anadolu Bölgesi’nde 2016-2017 eğitim öğretim yılında dördüncü
sınıfta öğrenim gören 25 öğrenci ve bir öğretmendir. Araştırmanın veri toplama aracı, araştırmacı
tarafından hazırlanan görüşme formlarıdır. Biri öğretmene, diğeri öğrencilere
yönelik olmak üzere iki farklı görüşme formu hazırlanmıştır. Verilerin
analizinde betimsel analiz yönteminden yararlanılmıştır. Buna göre öğretmen
ödevleri eğitsel (derse hazırlık, ders tekrarı, değerlendirme ve genişletme) ve
eğitsel olmayan (sorumluluk bilinci aşılama, araştırma becerisini geliştirme ve
veli ile etkileşimi artırma) amaçlara yönelik olarak vermektedir. Öğrenciler
ise ev ödevlerine yönelik genel olarak olumlu görüşlere sahiptir. Öğretmenin ev
ödevi verirken oluşturduğu beklentilerin de genel anlamda öğrencilerde
karşılığını bulduğu ifade edilebilir.
OKUL MÜDÜRLERİNİN KAYNAŞTIRMA EĞİTİMİNE YÖNELİK YAPILAN YASAL DÜZENLEMELERE İLİŞKİN GÖRÜŞLERİNİN BELİRLENMESİ
Authors: YAZICIOĞLU Tansel 
Published: March 2020

Bu araştırmanın amacı, ilkokul ve ortaokullarda görev yapan okul
müdürlerinin, kaynaştırma eğitimi ile ilgili yapılan yasal düzenlemeler
hakkındaki görüşlerini belirlemektir. Araştırma, 2018–2019 eğitim-öğretim
yılında Ankara İli Çankaya İlçesi’nde yürütülmüştür. Araştırmada, okul
müdürlerinin görüşlerini belirlemek amacıyla yarı yapılandırılmış görüşmeler
gerçekleştirilmiştir. Veriler, 2019 yılının Şubat ayında toplanmış ve cep
telefonunun ses kayıt uygulaması kullanılarak kaydedilmiştir. Veriler, nitel
veri analiz tekniklerinden içerik analizi ile analiz edilmiştir. Araştırmada
elde edilen bulgular, kendileriyle görüşme yapılan okul müdürleri ile
gerçekleştirilen görüşmelerden elde edilen verilerin analizi sonucu ortaya
çıkan temalar dikkate alınarak sunulmuştur.
Araştırmanın sonuçları, ülkemizde kaynaştırma eğitimine ilişkin yapılan
yasal düzenlemelerin yeterli olduğunu, ancak bazı konularda güncel yasal
düzenlemelere gereksinim duyulduğunu, yasal düzenlemelerin uygulanmasında ise
sorunlar yaşandığını ortaya koymuştur. Sonuç olarak ülkemizde özel gereksinimli
öğrencilerin eğitiminde önemli bir eğitim modeli olan kaynaştırma eğitimine
ilişkin yapılan yasal düzenlemelerin gözden geçirilmesi ve uygulamada mevzuata
ilişkin sorunların belirlenmesi gerekmektedir. Uygulayıcıların görüşlerine
dayalı olarak yapılan mevzuat düzenlemesinin uygulamadaki sorunları
azaltabileceği ve birçok yasal boşluğun önüne geçebileceği düşünülmektedir.
Seismicity of the Erguna Region (Northeastern China): Evidence for Local Stress Redistribution
Authors: Seredkina Alena I. , Melnikova Valentina I. , Radziminovich Yan B. , Gileva Nadezhda A. 
Published: March 2020

ABSTRACTWe consider the seismicity of the Erguna region in northeast China (48°–51° N, 117°–123° E) which is poorly studied from seismological point of view as it is characterized by a low level of seismic activity. We calculate focal parameters (focal mechanisms, scalar seismic moments, moment magnitudes, and hypocentral depths) for seven regional earthquakes with Mw 4.2–4.6 that occurred in 2000–2017 using global seismic data of Rayleigh- and Love-wave amplitude spectra and P-wave first-motion polarities recorded at regional stations. It has been shown that the study earthquakes are of small magnitudes (Mw 4.2–4.6), of various hypocentral depths (3–37 km), and are characterized by different kinematics in their sources (normal and thrust faults, strike slips). The different faulting mechanisms could reflect local stress redistribution in small-scale crustal blocks bordered by local short-length nonconnecting faults. The available geophysical and geological data evidence that the observed features of the seismic process in the Erguna region—low-seismic activity and inhomogeneity of the stress-strain field—are likely to be controlled by the structure of the crust and the upper mantle.
Urgent Measure of Geospatial Parameters for Flood Modeling in Indonesia
Authors: Andreas Heri , Sarsito Dina A , Yuherdha Angga Trysa , Pradipta Dhota 
Published: March 2020

Indonesia is prone to flood. Many areas including cities have a suffering flood in history until these recent days. Jakarta city, for example, had suffering flood since Dutch colonial time a few hundred years ago and even earlier until this recent year 2018. Besides Jakarta, Indonesia has other big cities like Bandung, Semarang, Surabaya and Medan which frequently suffered from the flood. Growing cities like Langsa, Pekanbaru, Palembang, Pamanukan, Garut, Cirebon, Pekalongan, Demak, Bojonegoro, Banjarmasin, Gorontalo, Bima are also suffering flood in almost regularly. The flood condition is different from time to time due to rain intensity and rivers capacity are leading to disaster. Low land areas such as coastal areas and peatland areas in many regions of Indonesia are experiencing the same disaster. Adaptation and mitigation should be taken against this flood disaster. In order to find the best adaptation and mitigation, first, we must understand the characteristic of the flood by creating flood models. Essential parameters of flood modeling would include geospatial parameters (e.g., Digital Elevation Model, Land use, and rivers geometry). Unfortunately for Indonesia's case, these geospatial parameters of the flood are still relatively weak. We can see that several flood models of Indonesia are in low accuracy spatially and temporarily. So, the measure of geospatial parameters is urgent. This paper will highlight this urgency.
Multiple Sensor on Clustering Wireless Sensor Network to Tackle Illegal Cutting
Authors: Mutiara Giva Andriana , Suryana Nanna , Mohd Othman 
Published: March 2020

This paper is intended to purpose a designed system using Wireless Sensor Network application. It is multiple sensors to tackle illegal cutting in the stage of a timber harvesting. This paper also discusses network performance and the costs of the purposed system. In every node in the networks, the system was built using a combined sound sensor and vibration sensor in which incorporated using Xbee Pro S2C. It is considered as a communication module at each sensor node and Arduino Nano to process the data. The Wireless Sensor Network has been designed in three networks with the configuration of master and slave nodes in each network. This system was testing using several scenarios to have the data performance of the networks and the performance of the proposed system in the small forest and the opened area. The costs of the purposed system also compared related to the previous system. The result showed the optimum distance that can be applied in the WSN network as a real-time application using Xbee Pro S2C is less than 30 meters; meanwhile the time consumed to communicate between nodes is below 5 s. Therefore, the more slaves in the subnetwork will affect the performance of the system. The proposed system runs smoothly as predicted in the purposed system. All the testing is 100% completed and can be handled by the proposed system.
Displasia tanatofórica. Reporte de un caso y revisión
Authors: Giraldo-Cuartas Alejandro 
Published: March 2020

Objetivo: presentar los hallazgos ecográficos de la displasia tanatofórica (DT) y su diagnóstico diferencial, desde el punto de vista del ultrasonido con la acondroplasia. Se presenta un caso clínico de una paciente gestante a quien se remitió con diagnóstico de feto con acondroplasia, y posterior a una ecografía de detalle fetal 2D-3D, se hizo el diagnóstico antenatal de displasia tanatofórica (DT), el cual se confirmó postmortem.Conclusión: se resalta la necesidad de afinar los criterios diagnósticos de la restricción del crecimiento, partiendo de reportar los hallazgos ecográficos en función del percentil de crecimiento fetal y no de la reasignación de una nueva edad gestacional con cada nueva ecografía, además se hacen algunas recomendaciones respecto al informe ecográfico.
Procesos de visualización en la resolución de problemas de matemáticas en el nivel de básica primaria apoyados en ambientes de aprendizaje mediados por TIC.
Authors: Gutiérrez Zuluaga Heiller , Aristizabal Zapata Jorge Hernán , Rincón Penagos Julián Andrés 
Published: March 2020

Las matemáticas contribuyen al desarrollo integral de los estudiantes para su integración a la sociedad; en el departamento del Quindío en los últimos años, se evidencia en los resultados de las Pruebas Saber de grado 3° y 5° que los estudiantes presentan diversas dificultades en matemáticas, una de las causas es la dificultad que les genera enfrentarse a la resolución de problemas. Esto se debe a que muchos docentes en ocasiones dan poca trascendencia a ciertos procesos como sucede con los procesos de visualización, como lo señala Zimmermann y Cunningham (2013, citado por Martinovic, Freiman y Karadag p. 213) la visualización en los procesos de aprendizaje de la matemática contribuye al desarrollo de una comprensión más profunda y significativa tanto de las ideas matemáticas y las relaciones entre los conceptos matemáticos, o desconocen el potencial que poseen los ambientes de aprendizaje y la integración de las TIC, que hacen trascender el aula física, enriqueciéndola con nuevas alternativas pedagógicas y dando a los estudiantes experiencias significativas y mejores oportunidades de aprendizaje. Por lo anterior se desarrolló la investigación bajo una metodología cualitativa de tipo interpretativa (Sampiere, Fernandez y Batista 2010), cuyo objetivo fue analizar incidencias de los procesos de visualización apoyados con ambientes TIC, en la resolución de problemas de matemáticas, por estudiantes de la educación básica primaria, encontrándose mediante la implementación de los software educativos que la visualización juega un papel muy importante en cuanto a los estilos de resolución de problemas de los estudiantes, de acuerdo a la categorización de las tareas propuestas.
Wpływ programu 500 plus na ewolucję demograficzną polskiego społeczeństwa
Authors: Błaszczyk Alina , Sawicka Justyna 
Published: March 2020

W artykule obserwacji i ocenie poddany został program 500 plus jako jeden z kluczowych determinantów obecnej sytuacji ekonomicznej polskiego społeczeństwa. Rozpatrywano znaczenie programu 500 plus, w szczególności biorąc pod uwagę jego wpływ na rozkład wydatków (przy rozróżnieniu wielkości dochodów rodzin), poziom dzietności czy stopę bezrobocia. Celem artykułu jest wskazanie korelacji pomiędzy wprowadzonym świadczeniem finansowym a takimi wskaźnikami ekonomicznymi, jak uzyskiwany poziom dochodów, wskaźnik urodzeń czy poziom zamożności. Do przeprowadzenia wnioskowania posłużyły badania wtórne z wykorzystaniem literatury przedmiotu, a także dostępnych ustaw i ich nowelizacji od 2016 roku.
Wskaźniki gospodarki o obiegu zamkniętym dla Unii Europejskiej i Polski
Authors: Kulczycka Joanna 
Published: March 2020

Gospodarka o obiegu zamkniętym jest jednym z kluczowych elementów europejskiej polityki gospodarczej, zmierzającej do racjonalnego wykorzystania zasobów i ograniczenia negatywnego oddziaływania produktów i procesów na środowisko w całym łańcuchu wartości. Efektem podejmowanych działań powinno być pozostawanie w gospodarce produktów, surowców i materiałów tak długo, jak to możliwe, a wytwarzanie odpadów powinno być w możliwie największym zakresie zredukowane. W tym celu konieczne jest właściwe opracowanie i dobranie wskaźników do strategii działania w zakresie GOZ. Stąd też celem artykułu jest dokonanie przeglądu proponowanych wskaźników i priorytetowych obszarów GOZ w UE i w wybranych krajach oraz zidentyfikowanie pozycji Polski w wybranych obszarach GOZ. Na tej podstawie oraz uwzględniając specyficzne cele GOZ w Polsce, wyszczególnione w krajowych dokumentach, zaproponowano wskaźniki istotne dla monitorowania transformacji gospodarki polskiej w kierunku GOZ.
The Western and the War Film: Clint Eastwood’s „American Sniper” as Genre Hybrid
Authors: Holtz Martin 
Published: March 2020

The article explores the similarities of Westerns and war films and the ways in which the two genres have cross-fertilized each other since World War II. Central to their similarities are their efforts to render violence as a “regenerative” Slotkin means to establish or defend American civilization. Since the Vietnam War, however, the Western has taken a revisionist turn, and its subsequent evocations in war films expose the frontier ideology of justified violence in the name of the advancement of American civilization as a failed ideological project and highlight the imperialist aggression that connects America’s westward expansion with its military efforts. Using the example of Clint Eastwood’s film American Sniper 2014, the article argues that the use of Western elements in contemporary films about the Iraq War adds a sense of moral ambiguity to the portrayal of the hero, who exhibits a pathological obsession with a Western image of the righteous protector of civilization that is ultimately destructive to himself and the society he wants to protect.WESTERN A FILM WOJENNY — SNAJPER CLINTA EASTWOODA JAKO GATUNKOWA HYBRYDAArtykuł jest eksploracją podobieństw między westernem a filmem wojennym i sposobów, w jakie obydwa gatunki wzajemnie się przenikały od czasu II wojny światowej. Głównym ich podobieństwem jest próba prezentowania przemocy jako „odradzającego się” Slotkin środka służącego ustanowieniu bądź obronie amerykańskiej cywilizacji. Jednakże od wojny wietnamskiej western przeszedł rewizjo­nistyczny zwrot, a jego kolejne ewokacje w filmach wojennych eksponują ideologię Pogranicza bę­dącą usprawiedliwieniem przemocy w imię zaawansowania amerykańskiej cywilizacji jako projektu ideologicznego upadłego i ukazują imperialistyczną agresję, która łączy amerykańską ekspansję na zachód z jej militarnymi wysiłkami. Na przykładzie Snajpera Clinta Eastwooda 2014 niniejszy esej przekonuje, że zastosowanie westernowych elementów we współczesnych filmach o irackiej wojnie przydaje moralnej dwuznaczności portretowi bohatera, przejawiającego patologiczną obsesję wester­nowym image’em prawego obrońcy cywilizacji, skrajnie destrukcyjnego wobec siebie oraz społeczeń­stwa, które chce osłaniać. Przeł. Kordian Bobowski