bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formulation, characterization and evaluation of nanoparticles based dry powder insufflation containing terbutaline sulphate and itraconazole for the treatment of asthma
Authors: Venugopalaiah Penabaka  , Kumar B  , Prasad N.B.L  
Published: January 2020

Many factors affect the pulmonary drug delivery and stability of the nanoparticles an acupuncture consisting of bronchial asthma. Present research envisages on the development of dry powder nanoparticles as insufflation a acupuncture consisting of bronchial asthma (allergy due to Aspergillus fumigatus) using physical mixing and spray drying. Different founding are prepared and characterized with suitable excipients like lactose and trehalose. The particle size distribution of nano milled and spray-dried particles of Terbutaline Sulphate and Itraconazole showed unimodal size distribution. The formulations prepared with trehalose as the carrier showed less Dv90, Dv50 and Dv10 values due to the fineness in the particles of trehalose when compared to lactose. The Dv50 and Dv10 values were in the range of mountains of 0.43-0.89 µm and 0.21–0.49 µm for all formulations, which shows the primary particle size in the nanometer scale. Smooth and nearly spherical particles were produced for spray-dried formulations when compared to milled formulations. Zeta potential comes across until be between +17±0.13 to +32±0.12, which explains the particles as moderately stable. MMAD values ranges from 3.19 µm to 4.78 µm for milled nanoparticles and 3.45 µm to 4.21 µm for spray-dried particles. Formulated nanoparticles exhibited good spreading properties, which will allow all the particles to deposition palmy profusion territories consisting of the lung. In-vitro drug release studies explains that spray-dried formulations of Terbutaline sulpahte and Itraconazole using lactose as excipients released the drug upto 98.9% and 99.1% in 180mts.
Microwave-Assisted Synthesis, Characterization and Antimicrobial Potencies of N-Substituted Iminothiazodin-4-One Derivatives
Authors: Sharad K. Awate  , Suresh V. Patil  , Ravindra S. Dhivare  , Renukacharya G. Khanapure  
Published: January 2020

The biggest and most multifaceted class of organic compounds includes heterocyclic compounds. Currently, several heterocyclic compounds are identified, and persistently gratefulness to tremendous synthetic work and synthetic usefulness, the number is increasing exponentially. In most fields of science, including medicinal, pharmaceutical, and agro-chemistry, heterocyclic compounds have a function, and biochemistry is also another area. In this research article, the green approach is administered for achieving the nitrogen, oxygen and sulphur centered five-membered heterocyclic derivatives. By taking the whole thing into account of hetero-chemistry, the moderately effective analog for gram-positive and gram-negative strains was shown for the five-membered heterocyclic compound series of N-substituted iminothiazodine-4-one and N-(benzylideneamino)thiazol-4(5H). The compound 6b showed very much active potency in accordance with the type standard drug the 6c compound against gram-positive Bacillus subtilis bacteria compared to the standard drugs and 6b indicated very active potency against the gram-negative Escherichia coli bacterial strain. The 5a and 6a compounds showed very strong activity against the fungal strain of Candida albicans and 6b or 6c were more active and highly potent than the standard drugs against Aspergillus niger species. In the view of this research, drive states that all the synthesized compounds might be used for the development for further heterocyclic entities.
Effectiveness of reflexology related interventions on physiological and biochemical parameters of metabolic syndrome among women
Authors: Elizabeth A J  , Aruna S  , Mercy P J  
Published: January 2020

The purpose of the study was First to evaluate the effectiveness of reflexology related interventions on biochemical and physiological parameters of metabolic syndrome among women; Second to find out the association between physiological and biochemical parameters of metabolic syndrome among women with socio-demographic variables. The study used a true experimental design with one experimental group and one control group. Data were collected from 40 self-help group women who were the members of Kudumbashree from a selected area in South India. Samples were collected by using multistage sampling. Reflexology related intervention was given to the experimental group for 12 weeks. The control group did not receive an intervention. Repeated measures ANOVA and t-test were used for data analysis. The study found there is a significant change in the physiological and biochemical parameters of metabolic syndrome among the experimental group as compared to the control group (p<0.001). Even if there is no statistically significant difference between the different groups, the observed difference is clinically significant. The study concludes that reflexology related intervention was effective in improving the parameters of metabolic syndrome. It can be implemented in the clinical setting for patients with metabolic syndrome and related lifestyle disorders
Characterization and antibacterial activity of cocos Nucifera L. Meat extract and powder as a drug and cosmetic agent
Authors: Dewi Melani Hariyadi  , Sisunandar  , Suciati  , Isnaeni  , Noorma Rosita  
Published: January 2020

Cocos nucifera L. or Kopyor coconut is the natural material plant that has nutrients content, including carbohydrates, proteins, fats and fatty acids. The potential of Kopyor coconut is mainly produced from water and soft flesh or meat. Some benefits of the meat have not been widely studied as an active drug agent. This study was aimed to identify and characterize kopyor meat extract and to test activity as an antibacterial agent. The maceration method was used to extract kopyor meat. The optimized extraction resulted in a yield of 23% efficiency. Kopyor meat extract was identified in terms of loss on drying, total ash, acid-insoluble ash, extract content and saponification value. Evaluation of the antibacterial activity of both dried meat kopyor and extract were conducted. The standardized extract had a loss on drying of 35%, total ash of 8.95%, acid-insoluble ash of 31%, and extract content soluble in water and ethanol of 56.9% and 0.6% respectively. The saponification value showed a value of 56. It was shown that both powder and Cocos nucifera extract had as same high activity as an antibacterial agent against Staphylococcus aureus, Pseudomonas aeruginosa and Staphylococcus epidermidis therefore this recommended for further formulation and evaluation as drug and cosmetic.
Erysiphe corylacearum’un neden olduğu külleme hastalığına karşı Giresun ili fındık üretim alanlarında kimyasal mücadele olanaklarının belirlenmesi
Authors: SEZER Arzu , BİLGEN Yusuf , DUYAR Ömür , KÖSE Çiğdem , GÜMÜŞ Ebru , ER Tuğba 
Published: January 2020

Fındık (Corylus
avellana L.), üretim ve ihracatında dünya lideri olan Türkiye’nin en önemli
tarımsal ürünlerinden biri olup, özellikle Karadeniz Bölgesi’ndeki çok sayıda
ailenin ana geçim kaynağıdır. Zaman zaman görülen olumsuz hava koşulları
yanında, bazı fındık hastalık ve zararlıları nedeniyle oluşan kayıplar geniş
bir üretici kitlesini ve ülke ekonomisini çok olumsuz yönde etkilemektedir.
Fındıkta son yıllarda Erysiphe
corylacearum U. Braun &amp; S. Takam.’un neden olduğu külleme hastalığı
önemli verim ve kalite kayıplarına neden olmuş ve hastalığa karşı kültürel
önlemlere ilaveten kimyasal mücadele gerekliliği de ortaya çıkmıştır. Bu
çalışma Giresun fındık üretim alanlarında E.
corylacearum’un neden olduğu külleme hastalığına karşı uygun bir ilaçlı
mücadele programı oluşturmak amacıyla yürütülmüştür. 2015 yılında iki program (Program B ve
Program C), 2016 yılında üç program (Program A, Program B ve Program C)
dahilinde, arazi koşullarında bazı bitki koruma ürünlerinin (Fluopyram 200 g/l
+ Tebuconazole 200 g/l, Triadimenol %50, Azoxystrobin 200 g/l + Difenoconazole
125 g/l, Myclobutanil 245 g/l, Thiophanate methyl %70 ve Kükürt (Sulphur) SC
800 g/l etkili maddeli) hastalığa karşı etkinlikleri belirlenmiştir. 2015
yılında yaprak değerlendirmelerine göre Kükürt uygulamaları hem Program B hem
de Program C’de aynı istatistik grupta yer alarak en yüksek etkinliğe sahip
olmuştur (sırasıyla %96.47 ve %93.59 değerleri ile). 2016 yılında da Kükürt
uygulamaları tüm programlarda hem yaprak (sırasıyla %94.16, % 94.30 ve % 85.96
etkinlik değerleri ile) hem de çotanak (sırasıyla %96.58, %92.43 ve %89.43
değerleri ile) değerlendirmelerine göre etkinliği en yüksek olan uygulama
olarak belirlenmiştir. Azoxystrobin 200
g/l + Difenoconazole, Triadimenol ve Fluopyram 200 g/l + Tebuconazole etkili
maddeli fungisitlerin etkinlikleri yıllar ve programlara göre farklılık
göstermekle birlikte genel olarak hastalık kontrolünde etkili oldukları
belirlenmiştir.
IMPLEMENTASI METODE EVEN-RODEH CODE UNTUK KOMPRESI KITAB UNDANG-UNDANG HUKUM PIDANA (KUHP) BERBASIS ANDROID
Authors: Batubara Nopiyah Belia , Zebua Taronisokhi 
Published: January 2020

Smartphones in addition to being a smartphone communication tool also functions as a tool for finding information. One application that is currently widely used by students and the public is KUHP application that run in mobile. KUHP application is an application that contains material of criminal laws. The KUHP application has large material and is stored in the application database after it is installed. The large size of the database of the Criminal Code application causes the need for large memory space at mobile. This has become one of the causes of smartphone memory performance to be reduced and slow. Compression technique can be used as a solution to the problem above. Compression aims to compress large data sizes into smaller ones, so that the required storage space decreases. This study describes how to do the compression process of the KUHP application material based on the Even Rodeh Code algorithm. Based on the results of tests conducted to compress 280 bits of data, it was found that the size of the data after being compressed was 176 bits, with compression ratio is 62.8%, ratio of compression is 1.59 bits, and redundancy is 37.2%.Keywords: Compression, KUHP Aplication, Even Rodeh Code, Database
SISTEM PENDUKUNG KEPUTUSAN REKOMENDASI CALON KEPALA PUSKESMAS MENGUNAKAN METODE MULTI ATTRIBUTE UTILITY THEORY (MAUT) (STUDI KASUS: PUSKESMAS DESA LAMA SEI LEPAN)
Authors: Nasution Jamillah , Syahrizal Muhammad 
Published: January 2020

Desa Lama Health Center is a community health service center for first aid for local communities who want to seek treatment or consult about their health, which serves all public health problems in the fields of childbirth, treatment, outpatient care, hospitalization, baby posyandu and so forth. Decision Supporter. The problems faced by the Old Village Health Center are still using manual methods, especially in determining the recommendation of candidates for Head of the Health Center. On this occasion the authors propose to make decisions for the selection of candidates for the head of the puskesmas using Microsoft Visual Studio 2008. From the results of prospective head centers using the Decision Support System by using the multi attribute utility theory(MAUT) method to facilitate employed in datermining the best decisions in Puskesmas Desa Lama Sei Lepan.Keywords: SPK Recommendation of Candidate Head of Puskesmas, MAUT
PERANCANGAN APLIKASI KOMPRESI FILE VIDEO MENGGUNAKAN ALGORITMA INTERPOLATIVE CODING
Authors: Riyansyah Desvika 
Published: January 2020

The size of the video files is relatively large, long duration and has a good top kulithen it requires a large storage space. With a very large video file size, at the time of the move process could be the process of moving failed because the media storage space exceeds the limit and consume very much quota at the time of transfer. The solution to this problem is how the video file can be compressed to accelerate the process of transferring and saving the video files and saving the quota. In this research, the algorithm used is Interpolative Coding, using the different compression methods-the difference of each value, and the compression results will be profitable, because the delivery will be easier and saves your quota and saves storage space.Keywords: Video File compression, Interpolative Coding algorithm
PENERAPAN ALGORITMA BOYER MOORE PADA APLIKASI FILOSOFER BERBASIS WEBSITE
Authors: Sinaga Indra Jabinsan , Kembaren Ricky Crist G Imanta , Br Bangun Dessy Milbina , Marbun Nasib 
Published: January 2020

The philosopher is a scientist who is an expert in the field of philosophy or philosophy. A philosphere is generally able to think radically, rationally, competently, and have good logic. Filosofer has knowledge and extensive experience of science in the field of philosophy is something that can build a sense of optimism in general society, especially for students who are pursuing the field of philosophy to develop their knowledge related to philosophy, but a source of information that provides specifically for philosophers biographies are still limited so finding information is still difficult. Web application is one proof of current technological advances, web applications today can be utilized by many people and has become a necessity to access various kinds of important information. The philosophers web application built in this research is intended to make it easier for users to access information related to philosophers biographies that can have a positive impact on users. In the built-in web application philosophy is applied by Boyer Moore's algorithm. Keywords: Filosofer, Web, Algorithms, Boyer Moore.
IMPLEMENTASI ALGORITMA SPRITZ DAN SPREAD SPECTRUM UNTUK MENYEMBUYIKAN PESAN ENKRIPSI KEDALAM FILE AUDIO MP3
Authors: Iqbal Muhammad , Zebua Taronisokhi , Sianturi Ronda Deli 
Published: January 2020

Optimizing the security of confidential text messages is very important to protect the contents of messages from those who want to use or damage the message. The use of cryptographic techniques in securing data can still raise suspicion of the message that has been secured. This study explores how to use steganography techniques to coat encrypted message security based on steganography techniques. The spritz algorithm is a cryptographic algorithm that is used to obtain the cipher from the original message, while the spread spectrum method is a method used to hide the original data password into an image. Based on testing done by combining these two techniques, it is quite reliable to optimize the security of secret messages because others cannot see the existence of the cipher of the original data in plain sight.Keywords: Cryptography, Steganography, Spritz, Spread Spectrum, mp3
PENERAPAN ALGORITMA TURBO BOYER MOORE PADA APLIKASI KAMUS BAHASA INDONESIA - ALAS
Authors: Murtada Ismail Al , Marbun Nasib , Buulolo Efori , Aripin Soeb 
Published: January 2020

The base language is one of the regional languages used in Aceh Province, precisely in Southeast Aceh. The base language is basically divided into 3 (three) pieces of dialeg, namely upstream (subtle), middle (medium), and downstream (rough). As time goes on, the Alas language becomes increasingly forgotten because the younger generation prefers to learn foreign languages to keep up with the times so that many Alas communities, especially the younger generation, cannot communicate using the Alas language. To preserve the Alas language, a technology-based dictionary application is needed that is developing at this time to help young people learn the Alas language. Improving the accuracy of string matching in translating the Alas language into Indonesian in the application in the dictionary application used to study the Alas language in this study used the Turbo Boyer Moore string matching agorithm. The results of this study are in the form of desktop-based applications that can be used easily on a computer with the results of Indonesian language translation search into the Alas language with accurate stringency accuracy efficiently and efficiently with minimum time. Keywords : Regional Language, Alas-Indonesian Indonesian Dictionary, String Matching, Turbo Boyer Moore.
ANALISA METODE WEIGHTED SUM MODEL (WSM) PENERIMA KARTU INDONESIA PINTAR (KIP) KEPADA SISWA/I DI SD (SEKOLAH DASAR)
Authors: Saragih Marlina Drawati , Tambunan Heru Satria , Dewi Rafiqa 
Published: January 2020

Indonesia Smart Card is a cash assistance from the government given to students whose parents are less able to finance their education. As a continuation and expansion of the objectives of the Poor Student Assistance (BSM) program. KIP has the goal of increasing access for children aged 6 (six) to 21 (twenty one years). In Primary School 091329 in the recipient of the Smart Indonesia Card faces many problems As students who are entitled to receive assistance actually do not receive. because of that there were protests and demonstrations caused by Kartu Indonesia Pintar which were not on target. The criteria for Indonesian card recipients are smart social protection card holders, parents' income, no vehicles, no dependents, orphans. In its implementation, it certainly has obstacles in deciding who students get the smart Indonesian card. To solve the problem, a weighted Sum Model (WSM) decision support system can overcome this problem. By applying the Weighted Sum Model (WSM) which is relatively easy and fast, it is believed to be able to get the best results. This research can provide information to the school in the recipient of the Indonesia Smart Card (KIP) for the following year. Keywords: SPK, Weighted Sum Model (WSM), Receiver of Smart Indonesia Cards
SISTEM PENDUKUNG KEPUTUSAN DALAM MENENTUKAN GARDENER TERBAIK MENGGUNAKAN ALGORITMA PROFILE MATCHING
Authors: Latif Muhammad Abdul , Sembiring Rahmat W. , Suhada Drs. 
Published: January 2020

PT.ISS Indonesia is the best and the largest Integrated Facility Service company in Indonesia with service coverage for Facility services, catering services, access control and parking.There are several fields in the company, one of which is the gardener. Gardener is one of the important parts in the company that is responsible for plant maintenance and gardening of a government agency or lodging company. A gardener has responsibility in terms of providing flowers for decoration in rooms such as rooms, lobbies, restaurants and rest rooms. The selection of the best gardener is done manually so that it requires a strong memory and accuracy for a leader.To overcome this, a system is needed to support the mindset of a leader in making objective decisions. There are several methods in decision support systems that can be used, one of which is the Profile Matching algorithm, which is a simple method in decision support systems by comparing GAP between alternative values and criteria.It is hoped that this research can provide a solution in recommending the best gardener in the company.So that it can facilitate the leadership in making decisions.Keywords : decision support systems, best gardener, profile matching
PENERAPAN METODE ELECTRE II DALAM MENCARI FAKTOR HAMBATAN SISWA SULIT BERKONSENTRASI DALAM MATA PELAJARAN
Authors: Putri Nirwanda Desnila , Poningsih Poningsih , Irawan Irawan 
Published: January 2020

Education is an effort specifically by goverments to provide the generation with appropriate academic potentials through which the successors attain the required capabilities to survive the natiions. .The process this transfer of information is carried out in school. But still, every thing does not run as smoothly as expected. The purpose of this research is to identify the problems serving as barrcades affecting the students to achieve the goals of learning.For a solution, the writer suggests the use of algorithm ELECTRE II as calculation to discover the best alternative. This method is implemented into an application of Vb Net 2010. The result obtined is A03 having best alternative while the biggest average is friend.Keywords: Decision Support System, Electre ii, Vb Net, Concentration, Students.
MENDETEKSI ORISINALITAS CITRA DIGITAL DENGAN MENERAPKAN METODE ADLER-32
Authors: Lahagu Jelita 
Published: January 2020

The development of digital images is now very rapid, where the processing of image data, documents on digital images make images easily created or manipulated easily, even without leaving a visual imprint for users to manipulate an image. The ease in making and changing an image can damage the credibility of the originality / authenticity of the image in various aspects.Image is a combination of points, lines, shapes and colors to create an imitation of an object. Based on this, the pixel changes the original image so that it does not indicate the original image or the image has been manipulated. Thus the detection of the image can be known the authenticity of an image using the Adler-32 Algorithm. Small changes of pixels do not make the image content detected by the human eye. This is explained in pixels like the long width in the image. The basis of this research is to detect the originality or authenticity of a digital image. Keywords : Image, Originality, Manipulation, Adler-32
ANALISA TESTIMONIAL DENGAN MENGGUNAKAN ALGORITMA TEXT MINING DAN TERM FREQUENCY- INVERSE DOCUMENT FREQUENCE (TF-IDF) PADA TOKO ALLMEEART
Authors: Simatupang Meylita Putri , Utomo Dito Putro 
Published: January 2020

E-commerce or often referred to as an online shop is the latest trend of the community in carrying out shopping activities, first before the rise of e-commerce companies like today the community to meet their needs still rely on distros around the customer lives, or to a shopping place but now it has switch to shoop online. The advantages offered by online shoop are the relatively low prices, no need to shop locations, and guarantee goods, it has an impact on retail shops that are increasingly lonely. Testimonials are one of the techniques carried out to convince customers to shop at e-commerce they have, testimonials are the responses of buyers for their experience of shopping in an e-commerce application starting from the payment process until the goods are received, the more positive experiences conveyed in the testimonials, the customer who have not shopped on an e-commerce application will be more convinced to shop. Testimonials on an e-commerce application are not always positive, there are times when testimonials are delivered by negative buyers. The customer's problem is the unavailability of percentages or information on the number of buyers with positive and negative shopping experiences because in general testimonials are only delivered in the form of a list.Keywords: Testimonial Analysis, Text Mining Algorithm, Term Frequency-Inverse Document Frequency (TF-IDF)
PENERAPAN DEMPSTER-SHAFER PADA SISTEM PAKAR DIAGNOSA PENYAKIT AKIBAT VIRUS VARICELLA-ZOSTER
Authors: Ritonga Rohima 
Published: January 2020

Varicella-zoster is a virus that can cause varicella and shingles. This disease is referred to as chicken pox because bubbles or boils that form on the skin when it bursts out with water. This disease is very easy to spread to others, especially children who have never been exposed to varicella-zoster. The spread of this virus occurs through the air and direct contact with sufferers The expert system is one branch of AI that makes broad users specific to solving expert human-level problems. Varicella zoster is a virus that can cause varicella and shingles. The resulting software is able to diagnose certainty value calculations using the Dempster-Shafer method, using a visual basic programming language that can act like an expert. This system can be used as a consultation media.Keywords: Expert System, Varicella Zoster, Dempster Shafer