bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concomitant using of topical carrageenan-kappa and oral vitamin D against 7, 12-dimethylbenz[a]anthracene induced-oral cancer in rats: A synergism or an antagonism effects
Authors: Ali Aseel J , Al-Juboori Jamal N.A. , Al-Nimer Marwan 
Published: July 2020

Objective: ?-carrageenan is a food stabilizer agent which has an antiproliferative effect, while vitamin D is a prohormone acts on the nuclear receptor and has a cytotoxic against cancer. This study aimed to show the synergistic effect of using topical ?-carrageenan and oral administration of the vitamin D on the 7, 12-dimethylbenz[a] anthracene (DMBA)-induced oral cancer. Material and Methods: fifty four male albino rats were randomly divided into seven groups: Acetone-treated served as control (Group I), vitamin D (5000UI)-treated (Group II), ?-carrageenan (1%)- treated (Group III), DMBA (0.5%)-treated (Group IV), Acetone, ?-carrageenan and DMBA were administered topically on both cheeks and palate, five times weekly for 12 weeks, while the vitamin D was administered orally twice weekly for 12 weeks. Groups V, VI, and VII were animals treated with vitamin D, ?-carrageenan, and both vitamin D and ?-carrageenan for 8 weeks after induction of oral cancer. At the end of the study, blood samples were obtained by cardiac puncture for determination of TNF-? and EGFR. Results: In the groups III and IV, serum EGFR showed significant low levels compared with Group I. In the Group VII, serum EGFR showed a significantly (p=0.014) low level compared with Group IV (614.3±69.7 pg/ml versus 882.4±45.6 pg/ml, respectively). Higher percentages of high levels of TNF-? were observed in the Groups VI and VII, while a lower percentage of EGFR was observed in the Group VI. Conclusion: both ?-carrageenan and vitamin D have antiproliferative effect against DMBA-inducing oral cancer by increasing the levels of TNF-? and suppressing the signaling pathway of EGFR. Concomitant using ?-carrageenan and vitamin D reduces the antiproliferative effect of each other. KeywordsOral cancer; 7, 12-dimethylbenz[a] anthracene; Vitamin D; ?-carrageenan; Epidermal growth factor receptor; Tumor necrosis factor-?.
Association of IL-33 gene rs16924159 polymorphism and recurrent pregnancy loss in Iranian Azeri women
Authors: Kamrani Amir , Rahmani Seyed Ali , Mosapour Parisa , Chavoshi Reza 
Published: July 2020

Abstract

Background
Recurrent pregnancy loss (RPL) referred to two or more consecutive abortions before 20th week of pregnancy. The imbalance of inflammatory factors such as interleukins (IL) can be a significant factor in the RPL. The aim of this study was to investigate association of interleukin-33 (IL-33) gene rs16924159 polymorphism and RPL in Iranian Azeri women.

Materials and methods
This case-control study consisted of 100 women with RPL as case group and 100 healthy controls with successful delivery. Genomic DNA was extracted from whole blood samples using salting out method. The fragments of the rs16924159 polymorphism were amplified by PCR and the genotyping was performed using DNA sequencing.

Results
The obtained results showed that frequency of GA genotype and G allele of rs16924159 polymorphism in the case group was significantly more than healthy controls (p = 0.033).

Conclusions
Generally, we showed that the IL-33 gene rs16924159 polymorphism may play an important role in risk of RPL in the Iranian Azeri women. However, further studies on different races and geographic areas can be useful in identification of effects of rs16924159 polymorphism on RPL.
Archaeology without antiquity
Authors: Nativ Assaf , Lucas Gavin 
Published: July 2020

AbstractAntiquity—the past—has been fundamental to archaeology from the very beginnings of the discipline, and it remains the central concept around which archaeological research is developed. Over the years, however, alternative ways of doing and thinking archaeology have come forth to challenge this orientation on the past. Despite their growth in scope and sophistication, these alternatives remain at the margins of our community. In this article, the authors argue that it is in the best interests of archaeology—both as a community and as a discipline—to not brush aside these alternatives but rather to afford them serious attention.
El sentido liberador del juego a través del ocio
Authors: Maldonado Martínez Gustavo Adolfo , Mendoza Negrete Jesús Erbey 
Published: July 2020

Se parte de los conceptos de ocio y tiempo libre como pautas para el juego y la recreación. Se realiza un análisis de la relación entre dichos conceptos, como un ejercicio que despliega el libre juego de las facultades del individuo para que su recreación no solo tenga un propósito de reposición de fuerzas sino de recreación de sí mismo y descanso en sí mismo. A fin de destacar sus conceptos como actividades liberadoras ante el imperativo del trabajo. Tal reflexión pone en discusión que el ocio y el juego han de complementar el trabajo de manera armoniosa y equilibrada pero no necesariamente en función del trabajo mismo. Finalmente se propone la comprensión del vínculo entre ocio y juego, posible a través de la recreación, no como un mero medio para descansar del trabajo, sino para el beneficio y realización de los seres humanos en sentido liberador.
Opioids or Steroids for Pneumonia or Sinusitis
Authors: Phang Karina G. , Roberts James R. , Ebeling Myla , Garner Sandra S. , Basco William T. 
Published: July 2020

OBJECTIVES:
To compare the frequency of opioid and corticosteroid prescriptions dispensed for children with pneumonia or sinusitis visits on the basis of location of care.

METHODS:
We evaluated 2016 South Carolina Medicaid claims data for 5 to 18 years olds with pneumonia or sinusitis. Visits were associated with 1 of 3 locations: the emergency department (ED), urgent care, or the ambulatory setting.

RESULTS:
Inclusion criteria were met by 31 838 children. Pneumonia visits were more often linked to an opioid prescription in the ED (34 of 542 [6.3%]) than in ambulatory settings (24 of 1590 [1.5%]; P ≤ .0001) and were more frequently linked to a steroid prescription in the ED (106 of 542 [19.6%]) than in ambulatory settings (196 of 1590 [12.3%]; P ≤ .0001). Sinusitis visits were more often linked to an opioid prescription in the ED (202 of 2705 [7.5%]) than in ambulatory settings (568 of 26 866 [2.1%]; P ≤ .0001) and were more frequently linked to a steroid prescription in the ED (510 of 2705 [18.9%]) than in ambulatory settings (1922 of 26 866 [7.2%]; P ≤ .0001). In logistic regression for children with pneumonia, the ED setting was associated with increased odds of receiving an opioid (adjusted odds ratio [aOR] 4.69) or steroid (aOR 1.67). Similarly, patients with sinusitis were more likely to be prescribed opioids (aOR 4.02) or steroids (aOR 3.05) in the ED than in ambulatory sites.

CONCLUSIONS:
School-aged children received opioid and steroid prescriptions for pneumonia or sinusitis at a higher frequency in the ED versus the ambulatory setting.
O ENSINO DE PORTUGUÊS EM CURSOS DE ENGENHARIAS E DE CIÊNCIA E TECNOLOGIA EM UNIVERSIDADES POTIGUARES: UMA DEMANDA POR UM ENSINO PARA FINS ESPECÍFICOS
Authors: Martins Mário Gleisse das Chagas , Sales Maria Alice 
Published: July 2020

Na Resolução nº 11/2002, do Conselho Nacional de Educação (BRASIL, 2002), que institui as diretrizes curriculares dos cursos de engenharias nas universidades brasileiras, estabelece-se que o egresso de um curso de engenharia deve saber comunicar-se de forma escrita e oral. Da perspectiva dos Letramentos Acadêmicos (LEA, 2017, LEA; STREET, 1998, 2006), em que se crê que o letramento é uma prática cultural e, portanto, diferenciada pelos contextos em que ocorre, é legítimo questionar como os cursos de engenharia das universidades federais potiguares satisfazem essa demanda legal. O objetivo deste trabalho, portanto, é analisar os modos de institucionalização do ensino de português nos cursos de engenharia dessas instituições e também no curso de bacharelado em ciência e tecnologia, como primeiro ciclo de algumas das engenharias. Para tanto, realizou-se uma análise documental dos projetos pedagógicos dos referidos cursos de três instituições federais localizadas no estado do Rio Grande do Norte. A análise centrou-se em particular na identificação e na caracterização das disciplinas ligadas ao ensino de português, a partir das seguintes unidades de análise: título, ementa e referências bibliográficas. Os resultados revelam que a maioria das disciplinas voltadas ao ensino de português fundamenta-se em abordagens generalistas, em que não se consideram as necessidades comunicativas específicas da profissão.
Research on Optimization of "Deoxidation Alloying" of Molten Steel Based on Linear Programming
Authors: Li Anna , Xu Dongqing 
Published: July 2020

<p>Aiming at the optimization of the supporting solution for molten steel "deoxidation alloying", the cost of "deoxidation alloying" is minimized from an economic perspective. Using Excel, Eviews and spss software programming, through factor analysis, clustering dimension reduction, principal component analysis Multiple linear regression analysis and linear programming optimization analysis, the author found out the main factors that affected the yield of alloy elements. This paper establishes a multiple linear regression mathematical model that affects the main factors of alloy elements and yield. According to the reference alloy price, the linear programming model is adopted to find the optimal solution of alloy ingredients.</p>
Preserving Dutch colonial hegemony through incorporated islamic matrimonial system in the Netherlands East Indies
Authors: Muttaqin Entol Zaenal , Zaini Ahmad 
Published: July 2020

The growth of Islamic matrimonial system in the present Indonesia was originally formulated in the 19th century of the Netherlands colonialism. There are several discourses among Dutch scholars in establishing an applicable law system since there are various legal system existed, and finally the colonial government issued legal dualism in order to preserve their hegemony. Provoked by several scholars the new constitution in 1854 was approved. In that, the Islamic matrimonial system was assimilated into Adat law and therefore the Islamic marriage system was allowed to be practiced in its own way. This Islamic matrimonial system was formed as a law under Dutch controls. Accordingly, the paper discusses Dutch hegemony system through applicable Islamic matrimony, and the development of this marriage as the formation of preserving hegemony. This paper arguably investigates Dutch hegemony system through applicable of Islamic matrimony. The analysis is guided by following questions: first, what are the reasons behind the implementation of indigenous legal institution such as Islamic marriage in preserving hegemony? Second, to what extent does the Islamic matrimony persisted within the applicable policy? The methodology is critical analysis of legal history contents, the data mainly taken from legal manuscripts which is a comprehensive view of law from a particular critical vantage point: a way of doing law, perhaps doing things with law. This paper argued that Dutch Hegemony system is poles apart from many colonialism regimes, the incorporated of indigenous legal system has become a method to subjugate indigenous power. Therefore, Islamic Matrimony developed into ways according to colonial’s interest
Osteoporosis y Menopausia
Authors: Amaya León Hernando 
Published: July 2020

1. La osteoporosis constituye un grave problema del síndrome menopáusico.
2. Los ginecólogos debemos mirar esta enfermedad con mayor atención.
3. Es necesario hacer una investigación en nuestro medio sobre incidencia, factores raciales, nutricionales, etc.
4. La hidroxyprolina urinaria es ayuda de laboratorio importante en el diagnóstico diferencial de la enfermedad.
Incontinencia urinaria de esfuerzo en la mujer. Estudio radiológico
Authors: Medina Murillo Jorge E. , Corrales de Mesa Lucely 
Published: July 2020

La incontinencia urinaria de esfuerzo en la mujer ha sido un tema de interés científico para ginecólogos, urólogos, anatomistas y muchos otros investigadores que a través de los años han producido grandes contribuciones para la comprensión de este intrincado problema.
Valor diagnóstico del examen del fondo de ojo en pacientes embarazadas con hipertensión arterial
Authors: Sánchez T. Fernando , Gómez P. Jesús A. , Guevara J. Hugo , Santamaría H. Armando 
Published: July 2020

A 107 mujeres embarazadas que padecían hipertensión arterial les fue practicada biopsia renal percutánea y los hallazgos histopatológicos fueron relacionados con los cambios vasculares encontrados al examen del fondo de ojo.
En el 87,3 por 100 de las pacientes con Toxemia Gravídica Aguda (T- GA) el fondo de ojo fue normal, a pesar de que los cambios renales de toxemia fueron muy severos.
En el 86 por 100 de las embarazadas con Enfermedad Hipertensiva Crónica (EHC) se apreciaron alteraciones orgánicas de los vasos retinianos.
Las hemorragias, con o sin exudados, se observaron con una frecuencia mucho mayor en los casos de EHC que en aquellos con TGA.
Toxoplasmosis y embarazo
Authors: Duarte Contreras Alberto , Bustamante Alvarez Gilberto , Luzardo M. Luis Fernando , Palau G. Manuel José 
Published: July 2020

Presentamos dos historias de pacientes en gestación con toxoplasmosis concomitante. Hacemos un recuento somero de la historia, contagio, síntomas, evolución, pronóstico, tratamiento y profilaxis. Consideramos las dos contingencias que se pueden presentar en la gestante toxoplasmósica: la parasistemia adquirida antes del embarazo o durante la gestación.
Epidemiología del Cáncer del Cérvix en el Perú.
Authors: Bedoya H. Mariano , Galarza L. Carlos , Nagahata S. John 
Published: July 2020

Este estudio ha sido hecho en el Departamento de Ginecología y Obs- tetricia del Hospital General del Callao, con la revisión de 8.000 historias Clínicas de la especialidad entre los años 1969-1971 y de ellas se desprende que, la epidemiología del cáncer del cérvix uterino tiene íntima relación con la edad media de la mujer a partir de los 30 años; con una mayor paridad, con la precocidad en la vida sexual activa; con la pobreza con la falta de cultura y que posiblemente el futuro de la etiología está en el estudio de los Virus.
Amniocentesis Transabdominal y Embarazo Prolongado
Authors: Sánchez Torres Fernando 
Published: July 2020

El autor propone practicar sistemáticamente amniocentesis transabdominal cuando el embarazo se ha prolongado más de 42 semanas. La conducta a seguir estará sujeta a las características del líquido amniótico, así: Tipo I - Líquido abundante, con vérnix. Tipo II - Líquido más o menos abundante, de color cetrino, sin vérnix. Tipo III - Líquido escaso, teñido de meconio. En los dos primeros tipos debe permitirse la continuación del embarazo y practicar nuevas punciones a interva los prudentes. En los casos de líquido tipo III debe procederse inmediatamente a evacuar el útero.
Ruptura espontánea del hígado después de parto a término en embarazo asociado a toxemia, (Informe de un caso).
Authors: Riaño R. Mario 
Published: July 2020

Se hace una actualización del tema de la ruptura espontánea del hígado en pacientes con toxemia gravídica, en lo relativo a sus aspectos de incidencia, etiología, patología, diagnóstico, pronóstico y tratamiento. Además se presenta la Historia Clínica de un caso de esta entidad patológica ocurrido en una paciente toxémica y en puerperio, atendida en el Departamento de Obstetricia y Ginecología del Hospital Militar Central, en la que con diagnóstico previo se hizo tratamiento quirúrgico de la ruptura hepática con buenos resultados.
Efectos Secundarios del Diacetato de Etinodiol más Mestranol
Authors: Sánchez Laureano , Lucena Q. Elkin 
Published: July 2020

En el Hospital Universitario de San Ignacio funciona, desde 1965, la Clínica Familiar, que tiene por objeto la atención de pacientes interesadas en planificar su familia usando los métodos de continencia periódica o de terapia ovulistática.
Experimentación Clínica con un nuevo derivado de la Progesterona
Authors: Bernal B. Héctor Enrique 
Published: July 2020

Se estudia la posible acción pro-gestaciona I del compuesto 156/ 103 (4 acetato 17 capronato de alfa-dihi- droxiprogesterona) en 40 mujeres menopáusicas, seleccionadas con estudio de endometrio-citología vaginal-moco cervical y curva de pregnandiol, a quienes, previa administración de un estrógeno de acción prolongada, se les suministró el compuesto a dosis de 125 y 250 mlgrs. Los resultados no revelaron acción progestacional manifestada por cambios secretorios en el endometrio, ni tampoco modificación de las curvas de citología vaginal y moco cervical. En cambio se hizo presente un posible efecto estrogénico, para investigar el cual se estudiaron en una segunda etapa 10 nuevas mujeres menopáusicas, a quienes se administró únicamente el compuesto 156/103 hasta en dosis de 500 mlgrs. que determinaron efecto estrogénico en la vagina, pero no en el endometrio, de donde se concluye que la acción prolíferativa primitivamente anotada se debía al estrógeno de acción prolongada, que no alcanzó a ser modificada en sentido secretor por el cuerpo en estudio.
Incidencia del Cáncer en Colombia - 1965
Authors: Gaitán Márquez Eduardo 
Published: July 2020

Colombia está situada entre los 12?31' en su latitud norte y 4°13' por el sur. En relación con el Meridiano de Greenwich la longitud está comprendida entre 66º50' y 79º01'.La supe rficie de Colombia es de 1.138.338 Kms.2 los cuales están distribuídos 578.864 que corresponden a los Departamentos y 559.474 a las Intendencias y Comisarías.
对胸外肿瘤合并糖尿病患者围手术期护理
Authors: 明明 周 
Published: July 2020

<div><span>目的 观察胸外肿瘤合并糖尿病患者应用围手术期护理的护理效果。方法 分析我院2018年5月1日</span>-2019年5月1日收治的60例胸外肿瘤合并糖尿病患者进行研究,按照随机分组的原则,将所有入选患者均分为干预组和对照组,每组各有30例患者,对照组30例患者,行常规的护理措施,干预组30例患者,在常规护理的基础上增加给予围手术期护理干预,观察和对比两组患者的临床护理效果。结果 干预组患者的护理总有效率为96.7明显优于对照组的护理总有效率70差异具有统计学意义（p&lt;0.05)。结论 针对性的围手术期护理应用于胸外肿瘤合并糖尿病患者,有助于减少各种不良并发症的发生,护理效果显著,在今后临床胸外肿瘤合并糖尿病患者的护理中具有重要的借鉴意义。</div><div> </div>
体位护理在复杂输尿管结右手术患者中的应用
Authors: 亚娟 董 , 冬冬 李 
Published: July 2020

<p> 目的 观察并研究体位护理对复杂输尿管结石手术的影响 方法 选择 川年 1月一20叫1月在我院接受治疗的 52 例行输尿管结石手术患者 ，将其随机分为观察组（ 26 例）和对照组（ 26 例） ，进行了 步治疗 ，观察组组的治疗效果也得到了改善 。结果 对照宫和观察组在接受体位护理后进行 VAS 评分 ，观察组均优于对照 ，差异有统计学意义 CP &lt;o. 05） 。观察组的护理满意度为 96. 2 % ( 25/26 ） ，对照组的满 意度为 65. 4 % Cl 7/26 ） ，差异具有统计学意义 <br />CP &lt;o. 05 ） 。结论 体位护理临床治疗可以有效提高患者对 的满意度，减轻术后痛苦 ，减少失血量 ，减少手术时间并可以降低医疗成本 。</p>
Pedagogical practices based on areas of knowledge: Reflections on the technology use
Authors: Garbin Monica Cristina , Trombeta de Oliveira Edison , Pirillo Nadia Rubio , Telles Simone 
Published: July 2020

The appropriation of technologies in education must consider the specificities of each knowledge field and propose the demand for its pedagogical use. In distance learning (DL), which relies on the use of technologies, the reflection on the use of this resource becomes fundamental. Processes, methodologies and materials are usually standardised due to time and production costs. It is necessary to identify an intermediate point in this standardisation that takes into account the specificities of the knowledge fields. This study aims to discuss the pedagogical practices in DL considered appropriate to the knowledge fields, in the appropriate combination of contents, technologies and pedagogical practices. The methodology adopted is qualitative, using survey as a data collection tool. In conclusion, this article indicates that there are, actually, more effective teaching practices for each knowledge field. There are still recommendations in order to study deeply the real learning in each teaching practice.
Keywords: Higher education, distance learning, pedagogical practices, education technology, TPACK.
Teaching electrical engineering or technology in a fun way
Authors: Serafin Cestmir 
Published: July 2020

Combining physical and mental activities as a prerequisite for a well-rounded personal development is the benefit of technical kits, especially electronic ones. Such a combination also pushes the limits of the studentsâ€™ efficiency. When used correctly, the creativity of both students and teachers is developed on a superior developmental level of knowledge in terms of quality. Electrotechnical kits have many positive effects in school education, suitably supplement as well as support it, and are also one of its subject matters. Considering the fast, global development information technology is experiencing, there is a growing need to combine computer systems and electrotechnical kits in education. The goal of this paper is to provide a comparative and analytical insight into teaching general, primary-level technical subjects in the context of electrical engineering, especially of electrotechnical kits, and to define current trends in or approaches to the implementation of educational activities.
Keywords: Technical Education, electrotechnical kits.
Effects of sound-to-spelling friends and enemies in children's auditory rhyme decisions
Authors: Lipourli Eleni 
Published: July 2020

An experiment is reported, conducted on children of 9 and 11 years of age, that examined the possible effect of the relative number of sound-to-spelling friends and enemies the first word of a rhyming pair has on performance in the auditory rhyme judgment task. Friends are rhyming words with the same spelling of the rime (e.g., stream-dream and scheme-theme) and enemies are rhyming words with dissimilar spellings of the rimes (e.g., stream-theme and scheme-dream). It was predicted, following the Loosemore, Brown & Watson (1991) connectionist model of spelling, that the first word presented should activate the representations of its friends and inhibit the representations of its enemies and so the orthographic facilitation effect should be larger for those cases where the first word a rhyming pair has more friends than more enemies. The experiment reported in this paper found precisely the opposite pattern of results: the orthographic facilitation effect was only reliable for those cases when the first word had more enemies than friends. So it would appear to be the case that the degree of the activation of friends and the inhibition of enemies varies according to how many words are friends and how many words are enemies.

Keywords: rhyme judgment task; friends and enemies; orthographic facilitation effect; children.
El líder y la felicidad
Authors: García Silvia J. 
Published: July 2020

Para afrontar con éxito este mundo competitivo y obtener buenos resultados, las organizaciones necesitan mejorar el desempeño de sus directivos, no sólo en temas de gestión de recursos, sino también, en las de gestión de personas; y para ello, las competencias personales juegan un rol muy relevante. Actualmente ya no hablamos sólo de jefes o gerentes, sino de líderes, de personas capaces de trasmitir confianza y credibilidad y que a la vez logran que los demás estén motivados y promueven una visión compartida influyendo de manera positiva en cada miembro de su equipo de trabajo y en toda la organización.
¿La calidad cuesta?
Authors: Bouillon Adolfo 
Published: July 2020

La producción sin defectos es una meta de toda organización; no alcanzarla genera resultados indeseados en el largo plazo. La gestión de inventarios, los pronósticos, y la gestión de la calidad ayudan en la consecución del objetivo de rentabilidad. Los modelos de pronósticos deben analizarse en detalle para tomar decisiones adecuadas de producción. La gestión de la calidad procura impulsar una cultura empresarial de largo plazo. Estudios demuestran que los beneficios de largo plazo de la gestión de la calidad superan ampliamente sus costos de corto plazo.